# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Mannosyl_trans3 PF11051.8 RLN02136.1 - 2.1e-33 115.9 0.0 5.1e-32 111.3 0.0 2.3 1 1 0 1 1 1 1 Mannosyltransferase putative FPRL1_inhibitor PF16104.5 RLN02136.1 - 0.022 14.9 0.0 0.083 13.0 0.0 1.9 2 0 0 2 2 2 0 Formyl peptide receptor-like 1 inhibitory protein TUDOR_5 PF18359.1 RLN02137.1 - 3.9e-16 58.5 8.9 2.4e-06 27.1 0.2 3.3 3 0 0 3 3 3 3 Histone methyltransferase Tudor domain 1 DUF1325 PF07039.11 RLN02137.1 - 4.7e-13 49.4 0.2 0.0033 17.5 0.0 3.1 2 1 1 3 3 3 3 SGF29 tudor-like domain Tudor_3 PF18115.1 RLN02137.1 - 8.8e-12 44.7 0.0 0.0032 17.3 0.0 3.4 3 0 0 3 3 3 3 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 RLN02137.1 - 3.3e-11 43.5 3.2 0.00033 21.1 0.0 3.4 3 0 0 3 3 3 3 Agenet domain DUF4537 PF15057.6 RLN02137.1 - 1.4e-06 28.3 0.2 0.014 15.4 0.1 3.0 1 1 1 3 3 3 3 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 RLN02137.1 - 7.9e-06 25.6 7.0 0.049 13.4 0.2 3.2 3 0 0 3 3 3 2 Lamin-B receptor of TUDOR domain 53-BP1_Tudor PF09038.10 RLN02137.1 - 9.6e-05 22.3 3.6 0.84 9.6 0.1 3.1 2 1 1 3 3 3 2 Tumour suppressor p53-binding protein-1 Tudor TUDOR PF00567.24 RLN02137.1 - 0.032 14.2 0.1 17 5.5 0.0 2.8 2 1 1 3 3 3 0 Tudor domain DUF1541 PF07563.11 RLN02137.1 - 0.079 12.8 1.3 2.2 8.2 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1541) Tudor_2 PF18104.1 RLN02137.1 - 1.1 9.0 6.4 42 3.9 0.2 3.5 3 1 0 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain Orn_Arg_deC_N PF02784.16 RLN02138.1 - 0.0096 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Exo_endo_phos PF03372.23 RLN02141.1 - 1.9e-05 24.3 0.3 2.8e-05 23.7 0.3 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_S5 PF00333.20 RLN02181.1 - 3.7e-29 100.5 1.2 8.2e-29 99.4 1.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 RLN02181.1 - 2.9e-25 87.5 0.0 5.1e-25 86.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 RLN02181.1 - 0.29 11.7 13.8 0.57 10.8 13.8 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF4296 PF14129.6 RLN02183.1 - 0.002 18.7 2.2 0.4 11.3 0.2 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4296) Guanylate_cyc PF00211.20 RLN02184.1 - 4.5e-13 49.2 0.0 6.1e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain NfeD PF01957.18 RLN02184.1 - 0.14 12.6 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Glyco_hydro_47 PF01532.20 RLN02186.1 - 2.4e-104 349.8 1.0 4.9e-78 263.1 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 Peptidase_M41 PF01434.18 RLN02188.1 - 8.2e-63 211.7 0.1 1.2e-62 211.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 RLN02188.1 - 1.8e-42 144.9 0.0 3.5e-42 144.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RLN02188.1 - 9.3e-13 47.8 0.2 2.3e-12 46.5 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 RLN02188.1 - 1.6e-09 38.1 0.0 5.4e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 RLN02188.1 - 8.8e-05 22.5 0.2 0.0048 16.9 0.0 3.0 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RLN02188.1 - 0.0002 21.6 0.2 0.3 11.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain TIP49 PF06068.13 RLN02188.1 - 0.0025 17.1 0.2 0.0077 15.5 0.1 1.7 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 RLN02188.1 - 0.0054 16.9 0.1 0.022 14.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 RLN02188.1 - 0.013 15.8 0.4 0.21 12.0 0.2 2.5 1 1 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 RLN02188.1 - 0.015 14.7 0.0 0.056 12.8 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 RLN02188.1 - 0.024 14.4 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 RLN02188.1 - 0.035 13.8 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 RLN02188.1 - 0.044 13.3 0.0 0.3 10.6 0.0 2.2 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_14 PF13173.6 RLN02188.1 - 0.093 12.8 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RLN02188.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 RLN02188.1 - 0.3 10.5 1.2 0.61 9.5 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein EF-hand_7 PF13499.6 RLN02190.1 - 0.00017 22.0 0.3 0.0061 17.0 0.3 2.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN02190.1 - 0.0016 17.8 1.3 0.0042 16.5 0.1 2.3 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 RLN02190.1 - 0.0018 18.1 0.3 0.011 15.6 0.1 2.3 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN02190.1 - 0.023 14.2 0.0 0.056 13.0 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 RLN02190.1 - 0.069 13.1 0.2 0.45 10.6 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain Nsp1_C PF05064.13 RLN02191.1 - 0.45 10.3 10.3 2 8.2 2.8 3.4 2 1 0 2 2 2 0 Nsp1-like C-terminal region DUF2730 PF10805.8 RLN02191.1 - 2.4 8.3 8.2 2.1 8.5 2.8 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) PMEI PF04043.15 RLN02191.1 - 5.5 7.3 7.4 8.3 6.7 0.2 3.1 3 1 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor DUF4337 PF14235.6 RLN02191.1 - 6.3 6.9 9.2 11 6.1 4.4 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4337) TRM PF02005.16 RLN02192.1 - 1.5e-124 416.0 0.0 1.7e-124 415.8 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 RLN02192.1 - 0.0092 15.7 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 RLN02192.1 - 0.037 13.7 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 FAD_binding_1 PF00667.20 RLN02193.1 - 1.9e-60 204.2 0.0 2.9e-60 203.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 RLN02193.1 - 1.1e-32 113.2 1.3 1.7e-32 112.6 0.3 1.9 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 RLN02193.1 - 1.4e-19 70.7 0.0 4.1e-19 69.2 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 RLN02193.1 - 0.031 14.4 0.0 0.18 11.9 0.0 2.0 1 1 1 2 2 2 0 Ferric reductase NAD binding domain MOR2-PAG1_C PF14225.6 RLN02194.1 - 0.00014 21.8 0.2 0.00014 21.8 0.2 2.6 3 0 0 3 3 3 1 Cell morphogenesis C-terminal zf-MYND PF01753.18 RLN02195.1 - 1.9e-10 40.6 12.6 3.9e-10 39.7 12.6 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 RLN02195.1 - 0.041 14.2 8.7 0.11 12.8 8.7 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF1247 PF06851.11 RLN02195.1 - 0.34 10.9 2.6 12 5.8 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1247) Rhodanese_C PF12368.8 RLN02195.1 - 0.35 11.3 6.7 0.72 10.3 6.7 1.5 1 0 0 1 1 1 0 Rhodanase C-terminal zf-HIT PF04438.16 RLN02195.1 - 3.2 7.7 8.4 7 6.6 8.4 1.6 1 0 0 1 1 1 0 HIT zinc finger Kinesin PF00225.23 RLN02196.1 - 3.9e-14 52.3 0.1 2.8e-13 49.5 0.0 2.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RLN02196.1 - 3.5e-08 33.5 0.0 1.9e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding AAA_22 PF13401.6 RLN02196.1 - 0.86 9.9 0.0 0.86 9.9 0.0 4.6 3 2 3 6 6 6 0 AAA domain SIR2 PF02146.17 RLN02198.1 - 1.1e-50 172.1 0.0 1.4e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 RLN02198.1 - 0.0027 17.5 0.0 0.47 10.2 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 RLN02198.1 - 0.0029 17.4 0.1 0.0043 16.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF592) UvrC_HhH_N PF08459.11 RLN02198.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal IFT57 PF10498.9 RLN02199.1 - 0.27 10.2 12.9 0.086 11.8 9.3 1.8 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF421 PF04239.12 RLN02199.1 - 0.28 11.0 2.8 0.5 10.1 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF421) POPLD PF08170.12 RLN02200.1 - 9.1e-22 77.2 0.5 4.5e-21 75.0 0.0 2.3 2 0 0 2 2 2 1 POPLD (NUC188) domain POP1 PF06978.11 RLN02200.1 - 7.3e-13 49.0 19.1 1.3e-12 48.1 0.1 2.6 2 1 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 GCV_T PF01571.21 RLN02200.1 - 0.081 12.3 0.0 2.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Aminomethyltransferase folate-binding domain fn3 PF00041.21 RLN02201.1 - 1.7e-08 34.7 0.0 2.3e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Fibronectin type III domain MA3 PF02847.17 RLN02202.1 - 7.7e-33 112.9 1.8 2.1e-14 53.5 0.0 3.6 3 1 0 3 3 3 3 MA3 domain MIF4G PF02854.19 RLN02202.1 - 2.8e-22 79.4 6.6 2.3e-20 73.2 6.6 3.3 1 1 0 1 1 1 1 MIF4G domain NAM-associated PF14303.6 RLN02203.1 - 5.5e-06 27.2 6.2 5.5e-06 27.2 6.2 2.7 2 1 0 2 2 2 1 No apical meristem-associated C-terminal domain Mut7-C PF01927.16 RLN02204.1 - 1.1e-26 93.7 1.2 2.3e-26 92.7 0.2 2.0 2 0 0 2 2 2 1 Mut7-C RNAse domain tRNA_edit PF04073.15 RLN02204.1 - 5.8e-09 36.1 0.0 1.6e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain DUF5615 PF18480.1 RLN02204.1 - 0.12 12.1 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) Ion_trans PF00520.31 RLN02205.1 - 8.5e-05 21.9 1.7 0.00015 21.0 1.7 1.4 1 0 0 1 1 1 1 Ion transport protein BK_channel_a PF03493.18 RLN02205.1 - 0.028 14.6 0.0 0.061 13.5 0.0 1.6 1 0 0 1 1 1 0 Calcium-activated BK potassium channel alpha subunit DUF5367 PF17329.2 RLN02205.1 - 0.12 12.5 0.5 0.29 11.3 0.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5367) ANAPC4_WD40 PF12894.7 RLN02206.1 - 7.3e-12 45.4 3.8 0.066 13.5 0.0 5.7 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RLN02206.1 - 5e-10 39.8 5.8 7.7 7.6 0.0 7.7 6 2 1 7 7 7 4 WD domain, G-beta repeat IKI3 PF04762.12 RLN02206.1 - 1.3e-05 23.4 5.9 0.002 16.2 1.1 3.2 2 1 0 3 3 3 3 IKI3 family eIF2A PF08662.11 RLN02206.1 - 1.4e-05 25.1 0.3 0.16 11.8 0.1 4.3 2 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A SoxG PF04268.12 RLN02206.1 - 0.03 14.5 1.0 0.052 13.7 0.2 1.7 2 0 0 2 2 2 0 Sarcosine oxidase, gamma subunit family GTP_EFTU PF00009.27 RLN02207.1 - 3.3e-44 150.8 0.0 5.8e-44 150.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 RLN02207.1 - 1.9e-26 92.6 0.1 9.7e-26 90.3 0.0 2.3 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 RLN02207.1 - 1e-11 45.0 0.2 5.2e-11 42.8 0.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RLN02207.1 - 3.3e-05 24.0 0.1 0.00014 21.9 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN02207.1 - 0.093 12.3 0.0 7.6 6.0 0.0 3.0 3 0 0 3 3 3 0 Ferrous iron transport protein B DUF4746 PF15928.5 RLN02207.1 - 0.32 10.4 9.3 0.59 9.5 9.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Usp PF00582.26 RLN02207.1 - 1.1 9.8 6.5 1.4 9.4 4.9 2.1 2 0 0 2 2 2 0 Universal stress protein family BUD22 PF09073.10 RLN02207.1 - 1.5 8.1 12.1 2.3 7.4 12.1 1.2 1 0 0 1 1 1 0 BUD22 DREPP PF05558.12 RLN02207.1 - 2 8.3 17.0 2.2 8.1 15.9 1.5 2 0 0 2 2 2 0 DREPP plasma membrane polypeptide CDC45 PF02724.14 RLN02207.1 - 6.9 4.8 9.1 9.5 4.4 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein ThiD2 PF17792.1 RLN02208.1 - 0.002 18.6 1.8 0.027 14.9 0.2 2.5 1 1 1 2 2 2 1 ThiD2 family Apolipoprotein PF01442.18 RLN02208.1 - 0.0038 17.1 0.5 0.0038 17.1 0.5 2.8 2 1 1 3 3 3 2 Apolipoprotein A1/A4/E domain Sec34 PF04136.15 RLN02208.1 - 0.011 15.6 3.6 0.05 13.5 2.4 2.2 2 0 0 2 2 2 0 Sec34-like family DUF3584 PF12128.8 RLN02208.1 - 0.024 12.2 2.8 0.033 11.7 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.6 RLN02208.1 - 0.031 12.9 1.8 0.041 12.6 1.8 1.2 1 0 0 1 1 1 0 AAA domain CREPT PF16566.5 RLN02208.1 - 0.036 14.2 2.1 0.065 13.4 2.0 1.6 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour YscO PF07321.12 RLN02208.1 - 0.12 12.3 1.7 0.39 10.7 1.3 2.0 2 0 0 2 2 2 0 Type III secretion protein YscO Gp-FAR-1 PF05823.12 RLN02208.1 - 0.15 12.4 2.9 0.24 11.7 0.2 2.3 2 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Prominin PF05478.11 RLN02208.1 - 0.25 9.3 2.3 0.31 9.0 2.3 1.1 1 0 0 1 1 1 0 Prominin Pex19 PF04614.12 RLN02208.1 - 0.48 10.1 4.2 0.27 11.0 2.0 1.8 2 0 0 2 2 2 0 Pex19 protein family ApoC-I PF04691.12 RLN02208.1 - 1.5 8.8 5.1 0.99 9.4 0.5 3.0 3 1 0 4 4 4 0 Apolipoprotein C-I (ApoC-1) AAA PF00004.29 RLN02209.1 - 2.9e-15 56.9 0.0 5.7e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 RLN02209.1 - 5.9e-15 55.4 0.0 2e-14 53.7 0.0 2.0 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 RLN02209.1 - 1.3e-13 51.1 0.0 3.1e-10 40.1 0.0 2.4 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 RLN02209.1 - 1.1e-07 31.9 0.0 1e-06 28.8 0.0 2.1 1 1 1 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 RLN02209.1 - 3.3e-05 23.7 0.0 6.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 RLN02209.1 - 9e-05 22.3 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 RLN02209.1 - 0.00013 22.4 0.0 0.00025 21.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_assoc_2 PF16193.5 RLN02209.1 - 0.00066 20.0 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA_30 PF13604.6 RLN02209.1 - 0.0007 19.4 0.0 0.0035 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RLN02209.1 - 0.00085 19.6 0.4 1.7 8.9 0.0 2.9 2 1 1 3 3 3 2 AAA domain AAA_11 PF13086.6 RLN02209.1 - 0.00088 19.1 0.0 0.002 17.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 RLN02209.1 - 0.0013 18.7 0.0 0.021 14.7 0.0 2.2 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 RLN02209.1 - 0.0017 18.3 0.5 0.019 15.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 RLN02209.1 - 0.0019 17.8 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region ResIII PF04851.15 RLN02209.1 - 0.0041 17.1 0.0 0.057 13.4 0.0 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit TniB PF05621.11 RLN02209.1 - 0.0044 16.5 0.0 0.092 12.1 0.0 2.3 1 1 1 2 2 2 1 Bacterial TniB protein AAA_14 PF13173.6 RLN02209.1 - 0.0054 16.8 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 RLN02209.1 - 0.0063 16.3 0.2 0.066 13.0 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase DUF815 PF05673.13 RLN02209.1 - 0.0085 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 RLN02209.1 - 0.012 16.2 0.0 0.097 13.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 RLN02209.1 - 0.016 15.6 0.1 0.4 11.0 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 RLN02209.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 RLN02209.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 RLN02209.1 - 0.053 12.9 0.0 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 RLN02209.1 - 0.099 11.8 0.0 0.18 10.9 0.0 1.4 2 0 0 2 2 2 0 TIP49 P-loop domain SNF2_N PF00176.23 RLN02209.1 - 0.11 11.2 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain Amino_oxidase PF01593.24 RLN02222.1 - 6.4e-53 180.6 0.5 2.6e-51 175.4 0.5 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RLN02222.1 - 3.4e-10 40.0 0.2 1.5e-09 37.9 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 RLN02222.1 - 2.9e-06 26.2 1.3 0.00025 19.9 0.7 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 RLN02222.1 - 3.2e-06 26.6 0.4 0.00026 20.3 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 RLN02222.1 - 3.8e-05 23.0 1.1 6.4e-05 22.2 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 RLN02222.1 - 9.2e-05 22.9 0.9 0.0029 18.1 0.8 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RLN02222.1 - 0.00086 19.0 2.1 0.00086 19.0 2.1 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 RLN02222.1 - 0.0033 16.6 0.2 0.0033 16.6 0.2 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 RLN02222.1 - 0.0063 15.8 0.2 0.012 14.9 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 RLN02222.1 - 0.0068 15.5 1.4 0.0068 15.5 1.4 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 RLN02222.1 - 0.028 14.4 0.6 0.22 11.5 0.1 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 RLN02222.1 - 0.051 12.9 0.2 0.29 10.4 0.3 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 RLN02222.1 - 0.1 11.9 0.5 0.18 11.1 0.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 RLN02222.1 - 0.14 11.4 0.4 0.28 10.4 0.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RLN02222.1 - 1 8.5 3.7 0.45 9.7 0.9 1.7 2 0 0 2 2 2 0 FAD binding domain PUF PF00806.19 RLN02223.1 - 3.7e-60 196.3 11.5 4.2e-08 32.4 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 RLN02223.1 - 0.0014 19.0 1.3 7.4 6.9 0.0 4.2 3 1 1 4 4 4 3 CPL (NUC119) domain TPR_1 PF00515.28 RLN02224.1 - 3.6e-09 36.1 4.8 0.0015 18.3 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat C2 PF00168.30 RLN02224.1 - 2.3e-06 27.8 0.0 5.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain TPR_2 PF07719.17 RLN02224.1 - 7.4e-06 25.7 6.7 0.0022 18.0 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN02224.1 - 0.0029 17.8 0.5 2 8.7 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 RLN02224.1 - 0.0061 16.7 0.8 0.069 13.4 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN02224.1 - 0.017 15.4 5.2 0.28 11.5 0.1 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 RLN02224.1 - 0.27 11.0 2.7 11 5.8 0.1 3.1 3 0 0 3 3 3 0 TPR repeat PhoLip_ATPase_C PF16212.5 RLN02225.1 - 6.2e-76 255.4 16.6 1e-75 254.7 16.6 1.4 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RLN02225.1 - 4.1e-17 61.6 0.1 9.8e-17 60.4 0.1 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 RLN02225.1 - 4.7e-11 42.6 0.0 1.1e-09 38.2 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RLN02225.1 - 5e-07 30.2 2.8 0.029 14.6 0.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RLN02225.1 - 0.0022 17.6 0.1 0.027 14.0 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RLN02225.1 - 0.005 16.6 0.0 0.0089 15.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACBP PF00887.19 RLN02225.1 - 0.16 12.2 0.0 0.5 10.6 0.0 1.8 1 0 0 1 1 1 0 Acyl CoA binding protein TUDOR_5 PF18359.1 RLN02226.1 - 8.6e-08 31.8 0.0 0.00011 21.8 0.0 2.4 2 0 0 2 2 2 2 Histone methyltransferase Tudor domain 1 Tudor-knot PF11717.8 RLN02226.1 - 0.034 14.0 0.0 0.34 10.9 0.0 2.2 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain Trimer_CC PF08954.11 RLN02227.1 - 0.051 13.1 6.0 1.1 8.9 2.0 3.9 3 0 0 3 3 3 0 Trimerisation motif Fibin PF15819.5 RLN02227.1 - 5.6 6.7 7.7 13 5.5 7.3 1.7 2 0 0 2 2 2 0 Fin bud initiation factor homologue Ribosomal_L26 PF16906.5 RLN02228.1 - 1.2e-33 115.4 3.4 3e-33 114.1 3.3 1.7 2 0 0 2 2 2 1 Ribosomal proteins L26 eukaryotic, L24P archaeal Pkinase PF00069.25 RLN02228.1 - 1.8e-20 73.5 0.0 3e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN02228.1 - 2e-11 43.7 0.0 2.9e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KOW PF00467.29 RLN02228.1 - 1.4e-05 24.9 3.1 1.4e-05 24.9 3.1 2.3 3 0 0 3 3 3 1 KOW motif Kinase-like PF14531.6 RLN02228.1 - 0.0014 18.0 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN02228.1 - 0.017 14.5 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ACBP PF00887.19 RLN02229.1 - 5.5e-26 90.6 2.0 6.6e-26 90.3 2.0 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Mg_trans_NIPA PF05653.14 RLN02230.1 - 2.3e-14 53.2 11.3 3.1e-14 52.8 11.3 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 RLN02230.1 - 0.0028 17.9 6.0 0.0028 17.9 6.0 2.9 2 1 0 2 2 2 1 EamA-like transporter family DUF3619 PF12279.8 RLN02230.1 - 0.2 12.0 0.6 0.53 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) DUF2371 PF10177.9 RLN02230.1 - 8.1 6.6 7.2 3.8 7.7 3.2 2.5 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) TauE PF01925.19 RLN02231.1 - 2e-26 93.1 34.8 2e-17 63.6 5.7 2.7 3 0 0 3 3 3 2 Sulfite exporter TauE/SafE Mito_carr PF00153.27 RLN02232.1 - 3.9e-18 65.2 0.8 2.4e-13 49.8 0.1 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein TruD PF01142.18 RLN02234.1 - 9.6e-68 228.9 0.4 2.2e-61 207.9 0.0 3.9 2 1 1 3 3 3 3 tRNA pseudouridine synthase D (TruD) Pkinase PF00069.25 RLN02235.1 - 3.8e-48 164.1 0.0 1.9e-45 155.3 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN02235.1 - 5.3e-20 71.8 0.0 4.2e-18 65.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN02236.1 - 1.3e-35 123.1 0.0 1.7e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN02236.1 - 1.4e-33 116.3 0.0 1.9e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN02236.1 - 0.0086 16.0 0.4 0.018 14.9 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN02236.1 - 0.018 14.4 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN02236.1 - 0.047 13.0 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF1765 PF08578.10 RLN02237.1 - 0.00041 20.8 0.0 0.00096 19.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) His_Phos_2 PF00328.22 RLN02239.1 - 1.4e-08 34.5 0.2 0.0002 20.8 0.0 2.8 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) GAF PF01590.26 RLN02242.1 - 1.8e-07 31.8 0.0 3.5e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 GAF domain PP2C PF00481.21 RLN02243.1 - 7.2e-32 111.0 0.0 1.1e-31 110.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 RLN02243.1 - 4.2e-06 26.8 0.1 0.06 13.2 0.0 3.2 2 1 1 3 3 3 3 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 RLN02243.1 - 0.0018 18.0 0.0 0.0076 15.9 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PDEase_I PF00233.19 RLN02244.1 - 1.3e-65 221.4 5.4 1.3e-65 221.4 5.4 1.6 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 RLN02244.1 - 3.5e-29 102.1 0.1 6.7e-11 43.0 0.0 3.7 3 0 0 3 3 3 3 GAF domain GAF_2 PF13185.6 RLN02244.1 - 4e-25 88.7 0.0 2e-10 41.1 0.0 3.4 3 0 0 3 3 3 3 GAF domain GAF_3 PF13492.6 RLN02244.1 - 2.1e-09 37.8 0.0 0.046 14.1 0.0 3.8 3 0 0 3 3 3 3 GAF domain HD PF01966.22 RLN02244.1 - 0.1 12.9 0.6 0.26 11.5 0.6 1.7 1 0 0 1 1 1 0 HD domain peroxidase PF00141.23 RLN02245.1 - 0.00033 20.4 0.0 0.00058 19.6 0.0 1.4 1 0 0 1 1 1 1 Peroxidase RskA PF10099.9 RLN02245.1 - 0.0061 16.9 2.0 0.0068 16.7 2.0 1.0 1 0 0 1 1 1 1 Anti-sigma-K factor rskA AIRC PF00731.20 RLN02245.1 - 0.056 13.0 2.2 0.063 12.9 2.2 1.1 1 0 0 1 1 1 0 AIR carboxylase Asparaginase_C PF17763.1 RLN02245.1 - 0.1 12.8 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain bacHORMA_1 PF18138.1 RLN02245.1 - 0.1 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial HORMA domain family 1 SOR_SNZ PF01680.17 RLN02246.1 - 2.2e-110 367.3 13.7 2.6e-110 367.0 11.2 1.9 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.14 RLN02246.1 - 2.6e-08 33.5 10.5 4e-08 32.9 1.1 2.7 2 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 RLN02246.1 - 0.0002 20.5 3.0 0.063 12.4 0.0 2.5 3 0 0 3 3 3 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 RLN02246.1 - 0.0023 17.5 1.6 0.039 13.4 0.1 2.3 2 0 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.21 RLN02246.1 - 0.0063 15.7 0.3 0.29 10.3 0.0 2.5 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase TetR_C_27 PF17935.1 RLN02246.1 - 0.0069 16.4 0.0 0.02 14.9 0.0 1.8 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain IMPDH PF00478.25 RLN02246.1 - 0.0081 15.2 2.5 0.011 14.7 2.5 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain OMPdecase PF00215.24 RLN02246.1 - 0.022 14.4 2.7 1.6 8.2 0.0 2.5 2 1 1 3 3 3 0 Orotidine 5'-phosphate decarboxylase / HUMPS family NanE PF04131.14 RLN02246.1 - 0.024 13.8 3.9 0.037 13.2 0.1 2.7 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Fapy_DNA_glyco PF01149.24 RLN02246.1 - 0.037 14.6 0.1 0.19 12.4 0.0 2.0 2 0 0 2 2 2 0 Formamidopyrimidine-DNA glycosylase N-terminal domain NMO PF03060.15 RLN02246.1 - 0.12 11.7 8.7 0.063 12.7 0.7 2.4 2 0 0 2 2 2 0 Nitronate monooxygenase SYF2 PF08231.12 RLN02247.1 - 9.9e-26 91.0 6.1 1.5e-25 90.4 6.1 1.3 1 1 0 1 1 1 1 SYF2 splicing factor betaPIX_CC PF16523.5 RLN02247.1 - 0.0033 17.2 0.4 0.0061 16.4 0.4 1.4 1 0 0 1 1 1 1 betaPIX coiled coil TauE PF01925.19 RLN02248.1 - 3e-28 99.0 38.2 4.3e-17 62.6 8.4 3.0 3 0 0 3 3 3 2 Sulfite exporter TauE/SafE SET PF00856.28 RLN02249.1 - 1.6e-19 70.9 1.9 1.4e-18 67.9 2.3 2.4 2 1 0 2 2 2 1 SET domain AWS PF17907.1 RLN02249.1 - 3.9e-06 26.8 3.0 3.9e-06 26.8 3.0 2.6 2 0 0 2 2 2 1 AWS domain PHD PF00628.29 RLN02249.1 - 2e-05 24.4 9.1 2e-05 24.4 9.1 2.6 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 RLN02249.1 - 0.095 12.3 4.5 0.38 10.3 4.5 2.1 1 0 0 1 1 1 0 PHD-finger TPR_2 PF07719.17 RLN02252.1 - 1.1e-17 62.7 1.8 0.00088 19.2 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 RLN02252.1 - 1.7e-17 63.8 0.0 4.3e-08 33.7 0.0 5.6 4 1 2 6 6 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN02252.1 - 3.2e-13 48.9 0.0 0.011 15.5 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN02252.1 - 7.5e-10 38.2 0.0 0.12 12.7 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN02252.1 - 3.4e-09 36.9 0.6 0.011 16.1 0.0 5.1 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN02252.1 - 8.6e-09 35.8 3.1 0.00077 19.9 0.0 6.2 5 1 2 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN02252.1 - 1.5e-08 34.1 0.1 0.11 12.6 0.0 5.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN02252.1 - 1.6e-08 34.6 21.0 0.0037 18.0 0.0 7.8 7 2 2 9 9 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN02252.1 - 4.9e-07 29.3 0.0 0.044 13.5 0.0 4.3 2 1 2 4 4 4 2 TPR repeat TPR_9 PF13371.6 RLN02252.1 - 7.7e-07 29.2 2.2 0.043 14.0 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN02252.1 - 5.9e-06 26.0 0.1 3.1 7.8 0.0 4.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN02252.1 - 0.0001 22.4 0.0 0.028 14.8 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN02252.1 - 0.047 14.3 9.0 14 6.6 0.0 7.1 7 1 0 7 7 7 0 Tetratricopeptide repeat DUF842 PF05811.13 RLN02253.1 - 0.11 12.1 0.4 0.17 11.5 0.4 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) TLD PF07534.16 RLN02254.1 - 2e-18 66.9 0.0 3.3e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 TLD RhoGAP PF00620.27 RLN02254.1 - 1.2e-13 51.2 0.0 4.4e-13 49.3 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain ELMO_CED12 PF04727.13 RLN02254.1 - 1.1e-10 41.9 0.0 2.9e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 ELMO/CED-12 family RUN PF02759.19 RLN02254.1 - 6.4e-06 26.2 0.5 0.089 12.7 0.3 2.6 2 0 0 2 2 2 2 RUN domain Adeno_PX PF05829.12 RLN02254.1 - 0.23 11.3 0.4 0.54 10.2 0.4 1.6 1 0 0 1 1 1 0 Adenovirus late L2 mu core protein (Protein X) Sugar_tr PF00083.24 RLN02272.1 - 7.6e-100 334.9 24.4 8.7e-100 334.7 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN02272.1 - 1.2e-25 90.2 35.1 3.7e-18 65.6 8.2 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1388 PF07142.12 RLN02272.1 - 0.063 13.3 0.7 0.1 12.5 0.7 1.3 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) ABC2_membrane PF01061.24 RLN02273.1 - 4.1e-35 121.1 24.9 7.3e-35 120.3 24.9 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN02273.1 - 1.3e-20 74.3 0.0 2.6e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 RLN02273.1 - 0.0074 15.4 17.8 0.014 14.5 17.8 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.6 RLN02273.1 - 0.019 15.4 0.0 0.037 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 RLN02273.1 - 0.025 14.0 0.2 2.9 7.2 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 RLN02273.1 - 0.031 14.0 0.1 0.069 12.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN02273.1 - 0.05 13.9 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RLN02273.1 - 0.074 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 RLN02273.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase PDR_assoc PF08370.11 RLN02273.1 - 5.5 6.8 10.1 0.1 12.4 1.5 2.4 2 0 0 2 2 2 0 Plant PDR ABC transporter associated DUF1754 PF08555.10 RLN02275.1 - 9.4e-06 26.3 21.6 0.00011 22.9 21.6 2.1 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) FAM60A PF15396.6 RLN02275.1 - 0.62 10.0 9.3 0.69 9.9 9.3 1.0 1 0 0 1 1 1 0 Protein Family FAM60A PPL5 PF18168.1 RLN02275.1 - 1.5 8.0 6.5 1.7 7.9 6.5 1.0 1 0 0 1 1 1 0 Prim-pol family 5 Pkinase PF00069.25 RLN02277.1 - 5.2e-72 242.4 0.0 6.8e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN02277.1 - 1.9e-33 115.8 0.0 2.9e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN02277.1 - 0.038 13.3 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN02277.1 - 0.093 11.5 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 RLN02277.1 - 0.1 12.5 0.0 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family DDE_1 PF03184.19 RLN02281.1 - 6.5e-05 22.7 0.0 8.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Band_7 PF01145.25 RLN02295.1 - 2.2e-22 79.9 0.0 2.2e-22 79.9 0.0 2.9 1 1 1 2 2 2 1 SPFH domain / Band 7 family Glyco_hydro_67N PF03648.14 RLN02295.1 - 0.041 14.2 3.2 0.099 12.9 3.0 1.7 1 1 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus DUF3015 PF11220.8 RLN02295.1 - 0.13 12.1 3.7 0.33 10.8 3.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) DUF5403 PF17395.2 RLN02295.1 - 2.7 8.4 12.3 3.4 8.0 2.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5403) Band_7 PF01145.25 RLN02296.1 - 7.1e-18 65.2 3.7 1.3e-07 31.8 0.1 3.1 3 0 0 3 3 3 2 SPFH domain / Band 7 family Band_7_1 PF13421.6 RLN02296.1 - 0.00078 19.2 2.3 0.0049 16.6 0.0 2.3 2 0 0 2 2 2 1 SPFH domain-Band 7 family FapA PF03961.13 RLN02296.1 - 0.05 12.2 8.3 0.082 11.5 8.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A C_GCAxxG_C_C PF09719.10 RLN02296.1 - 0.14 12.5 2.2 0.25 11.6 2.2 1.4 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) RNA_pol_Rpb1_5 PF04998.17 RLN02296.1 - 1.7 8.0 4.9 2.7 7.4 4.9 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 ECH_1 PF00378.20 RLN02297.1 - 2.6e-31 108.8 0.6 4.8e-31 108.0 0.6 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RLN02297.1 - 2.9e-18 66.5 0.3 3.8e-18 66.1 0.3 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 RLN02298.1 - 1.9e-32 112.5 0.1 2.5e-32 112.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RLN02298.1 - 1.2e-17 64.4 0.1 2.5e-17 63.4 0.1 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Kinesin PF00225.23 RLN02299.1 - 7.7e-109 363.6 0.0 7.7e-109 363.6 0.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RLN02299.1 - 1.9e-23 83.1 0.0 8.7e-23 80.9 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding MIP-T3 PF10243.9 RLN02299.1 - 3.5e-11 43.1 0.0 2.1e-10 40.6 0.0 2.3 1 1 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain DUF737 PF05300.11 RLN02300.1 - 0.0031 17.9 6.1 0.0047 17.3 6.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF737) DUF733 PF05306.11 RLN02300.1 - 0.52 10.7 9.5 0.27 11.6 5.6 2.4 2 1 2 4 4 4 0 Protein of unknown function (DUF733) DUF1825 PF08855.10 RLN02301.1 - 4.6 7.2 9.2 4.2 7.4 0.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1825) Mvb12 PF09452.10 RLN02301.1 - 5.4 7.5 7.9 3.4 8.2 1.0 2.9 3 0 0 3 3 3 0 ESCRT-I subunit Mvb12 HECT PF00632.25 RLN02302.1 - 2.5e-58 198.0 0.0 4.8e-58 197.1 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MIB_HERC2 PF06701.13 RLN02302.1 - 1.1e-19 70.4 9.3 2.3e-16 59.8 4.4 2.9 2 0 0 2 2 2 2 Mib_herc2 SPRY PF00622.28 RLN02302.1 - 5.1e-11 42.7 0.0 1.4e-07 31.7 0.0 3.0 2 0 0 2 2 2 2 SPRY domain Laminin_G_3 PF13385.6 RLN02302.1 - 1.8e-10 41.2 0.0 0.00058 20.0 0.0 4.0 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily CUB PF00431.20 RLN02302.1 - 7.3e-06 26.3 0.8 0.46 10.8 0.2 4.0 3 0 0 3 3 3 2 CUB domain SH3_3 PF08239.11 RLN02302.1 - 0.00051 20.3 0.3 0.0017 18.6 0.3 2.0 1 0 0 1 1 1 1 Bacterial SH3 domain Arm PF00514.23 RLN02302.1 - 0.0024 17.8 0.7 0.3 11.2 0.1 2.9 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN02302.1 - 0.017 15.3 0.1 0.11 12.9 0.1 2.6 1 0 0 1 1 1 0 HEAT repeat Pro_isomerase PF00160.21 RLN02303.1 - 3.6e-51 173.6 0.1 6.2e-51 172.8 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FKBP_C PF00254.28 RLN02303.1 - 3.1e-13 49.9 0.1 3.8e-06 27.1 0.0 2.9 2 1 1 3 3 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 RLN02303.1 - 2.4e-09 36.6 0.3 0.0014 18.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN02303.1 - 8.1e-05 22.5 0.3 0.85 10.0 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 RLN02303.1 - 0.00018 21.9 0.8 0.073 13.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN02303.1 - 0.00034 21.1 2.1 0.0018 18.8 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN02303.1 - 0.00037 20.2 0.5 0.8 9.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN02303.1 - 0.0053 17.4 1.0 0.2 12.3 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN02303.1 - 0.021 14.9 0.1 7.1 6.8 0.0 2.5 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 RLN02303.1 - 0.029 14.4 0.1 0.41 10.8 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 RLN02303.1 - 0.082 13.3 0.8 0.56 10.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1811 PF08838.10 RLN02303.1 - 0.1 12.8 1.1 2.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) TPR_12 PF13424.6 RLN02303.1 - 0.13 12.5 0.0 5.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 RLN02303.1 - 0.17 11.6 3.8 20 4.9 0.1 4.2 4 0 0 4 4 4 0 TPR repeat TPR_14 PF13428.6 RLN02303.1 - 0.61 11.1 2.0 3.2 8.8 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Cep57_CLD_2 PF14197.6 RLN02303.1 - 2 8.6 5.2 12 6.1 0.1 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 RNA_pol_Rpb1_1 PF04997.12 RLN02304.1 - 5.1e-21 75.3 0.0 5.8e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 Cytochrome_CBB3 PF13442.6 RLN02304.1 - 0.47 10.8 2.5 17 5.8 0.2 2.4 2 1 1 3 3 3 0 Cytochrome C oxidase, cbb3-type, subunit III Myb_DNA-bind_4 PF13837.6 RLN02305.1 - 7.7e-06 26.2 0.6 0.01 16.2 0.1 2.7 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain BRX_assoc PF16627.5 RLN02305.1 - 0.36 11.0 3.4 0.87 9.8 3.4 1.6 1 0 0 1 1 1 0 Unstructured region between BRX_N and BRX domain KIF1B PF12423.8 RLN02305.1 - 6.7 7.2 11.0 6.5 7.3 0.4 3.8 2 1 1 3 3 3 0 Kinesin protein 1B Myotub-related PF06602.14 RLN02306.1 - 1.5e-102 343.2 0.0 2e-102 342.7 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 RLN02306.1 - 0.021 14.8 0.1 0.049 13.6 0.0 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family DSPc PF00782.20 RLN02306.1 - 0.19 11.5 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain FYVE PF01363.21 RLN02307.1 - 3.8e-06 26.9 14.9 5.6e-06 26.4 13.3 2.1 1 1 1 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 RLN02307.1 - 0.00081 19.6 11.3 0.0029 17.8 11.2 2.1 1 1 0 1 1 1 1 FYVE-type zinc finger C1_1 PF00130.22 RLN02307.1 - 9 6.3 11.3 5.7 6.9 8.2 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.21 RLN02308.1 - 0.081 13.1 18.9 0.071 13.3 17.1 1.8 2 0 0 2 2 2 0 FYVE zinc finger FYVE_2 PF02318.16 RLN02308.1 - 0.11 12.7 14.8 0.88 9.8 15.1 2.3 1 1 1 2 2 2 0 FYVE-type zinc finger Siva PF05458.12 RLN02308.1 - 2.1 8.0 15.1 3.5 7.3 13.6 2.0 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Lipoxygenase PF00305.19 RLN02309.1 - 2.1e-18 66.1 0.4 9.2e-18 64.0 0.4 1.9 1 1 0 1 1 1 1 Lipoxygenase HTH_psq PF05225.16 RLN02322.1 - 1.7e-05 24.4 0.1 3.7e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 RLN02322.1 - 0.0023 18.0 0.4 0.0057 16.8 0.4 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 RLN02322.1 - 0.055 13.3 0.3 0.13 12.1 0.3 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Vac7 PF12751.7 RLN02322.1 - 0.19 11.2 5.7 0.48 9.8 5.7 1.7 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Glyco_hydro_3 PF00933.21 RLN02326.1 - 7.6e-52 176.6 0.0 9.8e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN02326.1 - 2.8e-36 125.4 0.0 5.2e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RLN02326.1 - 3.3e-11 43.1 0.1 8.3e-11 41.8 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain DHHC PF01529.20 RLN02340.1 - 1.6e-15 57.4 8.2 1.6e-15 57.4 8.2 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF3043 PF11241.8 RLN02340.1 - 2.1 8.3 0.0 2.1 8.3 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3043) DUF842 PF05811.13 RLN02341.1 - 3.1e-40 136.9 15.6 1.3e-39 134.9 15.6 1.7 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) GF_recep_IV PF14843.6 RLN02341.1 - 0.00015 21.6 7.6 0.0002 21.2 7.6 1.3 1 0 0 1 1 1 1 Growth factor receptor domain IV 7TMR-HDED PF07697.11 RLN02341.1 - 0.027 14.6 0.1 0.027 14.6 0.1 1.2 1 0 0 1 1 1 0 7TM-HD extracellular zf-Tim10_DDP PF02953.15 RLN02341.1 - 0.2 11.3 18.8 0.11 12.1 3.5 3.5 2 1 1 3 3 3 0 Tim10/DDP family zinc finger Col_cuticle_N PF01484.17 RLN02341.1 - 0.29 11.2 2.3 0.34 11.0 0.9 1.9 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain GIT_CC PF16559.5 RLN02341.1 - 1.2 9.1 6.7 1 9.3 4.4 2.2 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Vicilin_N PF04702.12 RLN02341.1 - 1.7 8.4 17.9 2.9 7.7 17.8 1.3 1 1 0 1 1 1 0 Vicilin N terminal region Sulfatase PF00884.23 RLN02342.1 - 9.1e-27 94.2 0.0 1.2e-26 93.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 RLN02342.1 - 1.1e-05 24.2 0.0 2.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 RLN02342.1 - 1.9e-05 24.4 0.0 9.1e-05 22.2 0.1 1.9 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase YkyA PF10368.9 RLN02343.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein IF3_N PF05198.16 RLN02344.1 - 3e-13 49.8 0.0 5e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 RLN02344.1 - 5.1e-08 32.8 0.0 1.1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain APOBEC4 PF18775.1 RLN02344.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 APOBEC4 RPN7 PF10602.9 RLN02345.1 - 1.5e-44 151.8 4.2 3.1e-44 150.7 2.2 2.3 2 1 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 RLN02345.1 - 9.7e-15 55.0 0.0 2.6e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.6 RLN02345.1 - 0.0043 17.0 0.0 0.67 10.1 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN02345.1 - 0.023 15.3 0.6 1.4 9.6 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN02345.1 - 0.057 13.6 4.4 5.7 7.3 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN02345.1 - 0.086 13.1 3.9 0.97 9.8 0.5 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat NCBP3 PF10309.9 RLN02346.1 - 2.1e-15 56.3 0.0 4.2e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Methyltransf_FA PF12248.8 RLN02346.1 - 2.4e-07 31.0 0.0 7.4e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Farnesoic acid 0-methyl transferase RNA_bind PF08675.11 RLN02346.1 - 6.4e-05 22.9 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 RNA binding domain Tho1_MOS11_C PF18592.1 RLN02346.1 - 0.17 11.7 5.4 3.6 7.5 0.2 3.3 2 1 1 3 3 3 0 Tho1/MOS11 C-terminal domain WD-3 PF09765.9 RLN02347.1 - 6.6e-80 268.5 0.0 8.4e-80 268.2 0.0 1.1 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 RLN02347.1 - 1.1e-26 92.8 2.0 4.7e-26 90.8 2.0 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 RLN02347.1 - 0.002 18.4 7.2 0.0033 17.7 3.0 2.5 2 0 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 RLN02347.1 - 0.13 12.3 0.2 0.13 12.3 0.2 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Spc7_C2 PF15577.6 RLN02347.1 - 0.22 11.6 0.1 3.3 7.9 0.1 2.3 2 0 0 2 2 2 0 Spc7_C2 zf-rbx1 PF12678.7 RLN02347.1 - 0.33 11.3 5.4 1.1 9.6 5.4 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING-like PF08746.11 RLN02347.1 - 0.43 10.9 2.2 1 9.7 2.2 1.6 1 1 0 1 1 1 0 RING-like domain zf-HC5HC2H PF13771.6 RLN02347.1 - 1.2 9.5 3.5 5.6 7.3 3.4 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain Cys_rich_CPXG PF14255.6 RLN02347.1 - 5.5 7.0 5.9 10 6.1 0.1 3.0 3 0 0 3 3 3 0 Cysteine-rich CPXCG CDC37_N PF03234.14 RLN02348.1 - 0.11 13.5 0.0 0.18 12.7 0.0 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Lipase_GDSL_2 PF13472.6 RLN02349.1 - 5.2e-23 82.4 0.0 1e-22 81.4 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RLN02349.1 - 1.7e-19 70.6 0.0 2.2e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ion_trans PF00520.31 RLN02350.1 - 7e-37 127.0 52.3 4.4e-21 75.2 10.1 5.1 5 1 0 5 5 5 3 Ion transport protein DUF2198 PF09964.9 RLN02350.1 - 0.023 14.8 2.8 1.1 9.3 0.1 3.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) FAM176 PF14851.6 RLN02350.1 - 0.16 11.6 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 FAM176 family EIF_2_alpha PF07541.12 RLN02351.1 - 4e-41 139.8 2.2 4.9e-41 139.5 0.1 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 RLN02351.1 - 9.7e-14 51.5 0.4 3.2e-13 49.8 0.4 1.9 1 0 0 1 1 1 1 S1 RNA binding domain CotH PF08757.11 RLN02352.1 - 2.4e-30 106.2 0.9 1.3e-14 54.5 0.5 2.1 2 0 0 2 2 2 2 CotH kinase protein Aldedh PF00171.22 RLN02354.1 - 5.5e-168 559.2 0.1 6.6e-168 559.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MazG-like PF12643.7 RLN02355.1 - 2.6e-09 37.2 0.0 1.5e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 MazG-like family MazG PF03819.17 RLN02355.1 - 2.8e-05 24.2 0.0 8.5e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain FAR1 PF03101.15 RLN02355.1 - 0.12 13.1 0.4 0.12 13.1 0.4 1.7 2 0 0 2 2 2 0 FAR1 DNA-binding domain DUF1126 PF06565.12 RLN02356.1 - 4.1e-87 286.9 0.2 4.3e-30 103.6 0.1 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain FYVE_2 PF02318.16 RLN02370.1 - 0.23 11.7 7.1 0.6 10.3 7.1 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 RLN02370.1 - 1.5 9.0 10.5 4.2 7.6 10.5 1.8 1 0 0 1 1 1 0 FYVE zinc finger FYVE PF01363.21 RLN02371.1 - 0.77 9.9 14.7 2.1 8.5 14.7 1.7 1 0 0 1 1 1 0 FYVE zinc finger FYVE PF01363.21 RLN02372.1 - 1.1 9.5 17.2 2.5 8.3 17.2 1.6 1 0 0 1 1 1 0 FYVE zinc finger Sad1_UNC PF07738.13 RLN02374.1 - 9.7e-23 80.6 0.0 2e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Pyridoxal_deC PF00282.19 RLN02374.1 - 1.4e-07 30.6 0.0 2.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF5611 PF18446.1 RLN02375.1 - 0.022 15.6 0.1 0.075 13.9 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5611) TUDOR PF00567.24 RLN02376.1 - 2.3e-09 37.3 0.0 3.4e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Tudor domain SNase PF00565.17 RLN02376.1 - 3.9e-07 30.5 0.0 5.5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue F-box-like PF12937.7 RLN02377.1 - 4.4e-08 32.9 0.0 7.6e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RLN02377.1 - 0.0015 18.4 0.2 0.0031 17.4 0.2 1.5 1 0 0 1 1 1 1 F-box domain FKBP_C PF00254.28 RLN02378.1 - 2.2e-08 34.3 0.0 2.6e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase_Tyr PF07714.17 RLN02379.1 - 2.5e-28 99.1 0.0 4.1e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN02379.1 - 4.7e-22 78.6 0.0 8.3e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RLN02379.1 - 0.00064 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like HAV_VP PF12944.7 RLN02379.1 - 0.069 13.1 0.0 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 Hepatitis A virus viral protein VP IML1 PF12257.8 RLN02384.1 - 1.4e-80 270.4 0.0 2e-80 270.0 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 PEPCK_ATP PF01293.20 RLN02391.1 - 0.00096 17.9 0.0 0.0016 17.2 0.0 1.3 1 1 0 1 1 1 1 Phosphoenolpyruvate carboxykinase PEX11 PF05648.14 RLN02392.1 - 6.4e-29 101.0 0.6 7.2e-29 100.8 0.6 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Med23 PF11573.8 RLN02393.1 - 0.29 8.7 0.0 0.42 8.2 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 23 EGF_2 PF07974.13 RLN02394.1 - 1.4e-15 57.3 62.6 1.2e-05 25.5 6.5 5.5 5 0 0 5 5 5 5 EGF-like domain MORN PF02493.20 RLN02394.1 - 0.13 12.2 0.8 12 6.0 0.1 3.5 3 0 0 3 3 3 0 MORN repeat Laminin_EGF PF00053.24 RLN02394.1 - 0.23 11.7 55.3 0.28 11.4 7.4 4.8 3 1 1 4 4 4 0 Laminin EGF domain ATG_C PF09333.11 RLN02395.1 - 1.1e-06 28.9 0.0 9.1e-05 22.7 0.0 3.0 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain Glyco_transf_28 PF03033.20 RLN02395.1 - 1.8e-05 24.8 0.0 0.0035 17.4 0.0 2.7 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 RLN02395.1 - 6.8e-05 21.9 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase VPS13_C PF16909.5 RLN02395.1 - 0.0011 18.7 0.1 0.0032 17.3 0.1 1.7 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Glyco_tran_28_C PF04101.16 RLN02395.1 - 0.045 13.7 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain COesterase PF00135.28 RLN02396.1 - 2.1e-58 198.5 3.4 1.4e-57 195.8 3.4 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RLN02396.1 - 0.029 14.2 0.5 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold UPF0203 PF05254.12 RLN02397.1 - 3.9e-11 43.0 6.7 3.9e-11 43.0 6.7 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0203) LEA_4 PF02987.16 RLN02397.1 - 3.4e-06 27.0 27.9 0.0011 19.0 18.5 2.7 2 0 0 2 2 2 2 Late embryogenesis abundant protein Apolipoprotein PF01442.18 RLN02397.1 - 0.0052 16.7 21.7 0.0091 15.9 21.7 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain CX9C PF16860.5 RLN02397.1 - 0.029 14.4 4.3 0.3 11.1 0.8 2.4 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, YtxH PF12732.7 RLN02397.1 - 1.9 9.1 24.7 5.8 7.5 9.8 3.2 1 1 1 2 2 2 0 YtxH-like protein DivIVA PF05103.13 RLN02397.1 - 8.8 6.4 24.6 0.39 10.8 10.9 2.4 1 1 1 2 2 2 0 DivIVA protein PH PF00169.29 RLN02398.1 - 7.4e-16 58.6 0.2 4.3e-10 40.0 0.0 2.8 2 1 0 2 2 2 2 PH domain PH_8 PF15409.6 RLN02398.1 - 1.2e-06 28.8 0.0 1.4e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 RLN02398.1 - 6.7e-06 26.5 2.6 0.0017 18.8 0.5 2.9 2 2 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.6 RLN02398.1 - 0.0054 17.0 0.5 0.016 15.5 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 RLN02398.1 - 0.0074 16.6 0.0 4.2 7.8 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain 6PF2K PF01591.18 RLN02399.1 - 6.3e-65 218.6 0.1 8.6e-65 218.2 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 RLN02399.1 - 1.1e-21 77.4 0.0 2.3e-21 76.4 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 RLN02399.1 - 1.4e-08 35.0 0.1 2.5e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 RLN02399.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Lant_dehydr_C PF14028.6 RLN02399.1 - 0.15 11.6 0.2 0.24 10.9 0.2 1.2 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term ASH PF15780.5 RLN02400.1 - 8.1e-24 83.7 3.6 0.028 14.6 0.2 10.3 11 0 0 11 11 11 7 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 RLN02400.1 - 0.00038 20.6 7.1 0.82 9.9 0.4 4.7 5 0 0 5 5 5 2 Flagellar-associated PapD-like Motile_Sperm PF00635.26 RLN02400.1 - 0.00056 19.7 0.0 3.7 7.4 0.0 6.1 7 0 0 7 7 7 1 MSP (Major sperm protein) domain UreE_N PF02814.15 RLN02400.1 - 0.0038 16.8 0.2 0.09 12.4 0.1 3.2 3 0 0 3 3 3 1 UreE urease accessory protein, N-terminal domain CMAS PF02353.20 RLN02401.1 - 2.1e-06 27.2 0.8 3.2e-06 26.7 0.1 1.5 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 RLN02401.1 - 4.4e-06 27.3 0.2 4.4e-06 27.3 0.2 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN02401.1 - 4.4e-05 23.4 0.2 0.0014 18.5 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 RLN02401.1 - 0.002 17.6 0.1 0.015 14.8 0.0 2.2 3 0 0 3 3 3 1 Putative methyltransferase MetW PF07021.12 RLN02401.1 - 0.0031 17.1 0.2 0.0054 16.4 0.2 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 RLN02401.1 - 0.015 15.2 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 RLN02401.1 - 0.016 14.5 0.0 0.023 14.0 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase domain DOT1 PF08123.13 RLN02401.1 - 0.02 14.4 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.19 RLN02401.1 - 0.045 13.5 0.6 0.66 9.7 0.0 2.0 1 1 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 RLN02401.1 - 0.06 14.0 0.1 0.06 14.0 0.1 2.1 3 0 0 3 3 3 0 Methyltransferase domain FtsJ PF01728.19 RLN02401.1 - 0.17 11.9 0.2 0.32 11.1 0.1 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 RLN02401.1 - 0.22 11.3 0.0 0.22 11.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain U3_snoRNA_assoc PF08297.11 RLN02402.1 - 0.0082 16.8 0.6 0.0082 16.8 0.6 2.6 2 1 1 3 3 3 1 U3 snoRNA associated Nop53 PF07767.11 RLN02402.1 - 0.46 9.8 23.0 0.63 9.4 23.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Calcipressin PF04847.12 RLN02402.1 - 0.62 9.8 7.7 1.5 8.5 7.5 1.7 1 1 0 1 1 1 0 Calcipressin eIF3_subunit PF08597.10 RLN02402.1 - 2.4 8.0 20.6 3.4 7.5 20.6 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit MAT1 PF06391.13 RLN02402.1 - 2.7 7.8 19.3 2.3 8.0 18.2 1.4 1 1 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 RR_TM4-6 PF06459.12 RLN02402.1 - 4.2 7.1 13.8 5.3 6.8 13.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol PF00940.19 RLN02403.1 - 7.5e-45 153.5 0.6 5.6e-44 150.6 0.6 1.9 1 1 0 1 1 1 1 DNA-dependent RNA polymerase ADH_N PF08240.12 RLN02405.1 - 2e-09 37.3 1.7 1.1e-08 35.0 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Viral_Beta_CD PF04530.12 RLN02405.1 - 0.01 16.1 0.6 0.01 16.1 0.6 1.8 1 1 1 2 2 2 0 Viral Beta C/D like family HypA PF01155.19 RLN02405.1 - 0.077 13.0 2.5 0.1 12.7 2.5 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PolC_DP2 PF03833.13 RLN02405.1 - 0.28 9.0 1.1 0.31 8.9 1.1 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 EMP70 PF02990.16 RLN02407.1 - 4.5e-36 124.6 18.0 6.5e-36 124.1 18.0 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Myosin_head PF00063.21 RLN02408.1 - 6.4e-182 606.3 5.9 2.7e-181 604.2 5.9 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) CbiA PF01656.23 RLN02408.1 - 0.0033 17.5 0.0 0.01 15.9 0.0 1.8 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 RLN02408.1 - 0.0079 16.6 0.1 0.028 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Hpr_kinase_C PF07475.12 RLN02408.1 - 0.01 15.3 0.0 4.6 6.7 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain T2SSE PF00437.20 RLN02408.1 - 0.021 13.9 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 RLN02408.1 - 0.023 15.1 0.0 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RLN02408.1 - 0.028 14.8 0.2 0.52 10.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 RLN02408.1 - 0.031 14.6 0.1 0.29 11.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 RLN02408.1 - 0.066 12.7 0.0 8.7 5.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_6 PF12774.7 RLN02408.1 - 0.071 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region TLE_N PF03920.15 RLN02436.1 - 0.0068 16.5 4.7 0.0068 16.5 4.7 1.9 1 1 1 2 2 2 1 Groucho/TLE N-terminal Q-rich domain Exonuc_VII_L PF02601.15 RLN02436.1 - 0.016 14.8 6.6 0.018 14.7 6.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Imm42 PF15593.6 RLN02436.1 - 0.026 15.0 0.8 0.035 14.6 0.8 1.2 1 0 0 1 1 1 0 Immunity protein 42 DUF3426 PF11906.8 RLN02436.1 - 0.09 12.9 1.3 0.13 12.4 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3426) DUF2748 PF10871.8 RLN02436.1 - 0.4 9.3 4.1 0.49 9.0 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) ALS2CR8 PF15299.6 RLN02436.1 - 1.4 8.7 7.6 2.7 7.8 5.2 2.1 1 1 1 2 2 2 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 HSP90 PF00183.18 RLN02437.1 - 7.3e-199 661.9 24.4 1.1e-198 661.4 24.4 1.3 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 RLN02437.1 - 1e-12 48.5 0.0 2.4e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 RLN02437.1 - 6.9e-09 35.7 0.1 1.6e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4131 PF13567.6 RLN02437.1 - 0.21 11.2 0.0 0.41 10.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) CobT PF06213.12 RLN02437.1 - 0.31 10.4 43.7 0.1 12.0 13.2 3.2 3 0 0 3 3 3 0 Cobalamin biosynthesis protein CobT SOGA PF11365.8 RLN02444.1 - 0.033 15.3 7.9 0.033 15.3 7.9 3.6 1 1 3 4 4 4 0 Protein SOGA HALZ PF02183.18 RLN02444.1 - 0.68 10.2 10.5 5.3 7.4 1.6 3.6 2 1 1 3 3 3 0 Homeobox associated leucine zipper Striatin PF08232.12 RLN02444.1 - 1.5 9.4 29.7 0.09 13.4 10.5 3.2 1 1 2 3 3 3 0 Striatin family TMF_TATA_bd PF12325.8 RLN02444.1 - 3.5 7.9 30.6 1.9 8.7 11.6 3.2 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 RLN02444.1 - 8.9 6.7 32.0 2.5 8.5 15.2 2.2 1 1 1 2 2 2 0 Fez1 NAD_binding_6 PF08030.12 RLN02446.1 - 0.0058 16.8 0.0 0.0063 16.7 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Clathrin PF00637.20 RLN02447.1 - 0.0098 15.8 0.5 0.21 11.4 0.0 2.9 3 0 0 3 3 3 1 Region in Clathrin and VPS DS PF01916.17 RLN02448.1 - 6.5e-130 432.5 0.0 7.6e-130 432.3 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Vasculin PF15337.6 RLN02448.1 - 0.052 14.4 0.0 0.11 13.3 0.0 1.6 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 Metallophos PF00149.28 RLN02449.1 - 3.7e-08 34.1 0.0 7.4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FtsJ PF01728.19 RLN02450.1 - 9.5e-57 191.9 0.2 2.1e-56 190.8 0.2 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.12 RLN02450.1 - 1.2e-55 188.4 19.3 1.2e-55 188.4 19.3 4.3 4 1 2 6 6 6 1 Spb1 C-terminal domain DUF3381 PF11861.8 RLN02450.1 - 3.3e-38 131.1 16.0 3.3e-38 131.1 16.0 4.7 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) PB1 PF00564.24 RLN02451.1 - 3.9e-08 33.1 0.0 8.6e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 PB1 domain CUE PF02845.16 RLN02451.1 - 0.12 12.1 2.1 0.54 10.0 0.2 2.5 3 0 0 3 3 3 0 CUE domain Kinesin PF00225.23 RLN02452.1 - 6.8e-104 347.4 2.3 5.9e-103 344.3 0.0 2.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RLN02452.1 - 5.4e-45 153.0 0.1 1.7e-44 151.3 0.1 2.0 1 0 0 1 1 1 1 Microtubule binding WW PF00397.26 RLN02452.1 - 1.7e-08 34.4 2.7 3.3e-08 33.5 2.7 1.5 1 0 0 1 1 1 1 WW domain Filament PF00038.21 RLN02452.1 - 9.6e-05 22.1 18.7 9.6e-05 22.1 18.7 3.8 2 1 2 4 4 4 1 Intermediate filament protein DUF1730 PF08331.10 RLN02452.1 - 0.022 14.6 0.1 0.12 12.4 0.1 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) Spc7 PF08317.11 RLN02452.1 - 0.89 8.4 89.0 0.25 10.2 17.9 4.3 1 1 3 4 4 4 0 Spc7 kinetochore protein DUF2935 PF11155.8 RLN02452.1 - 9.5 6.6 15.6 0.68 10.3 1.4 4.1 2 1 3 5 5 5 0 Domain of unknown function (DUF2935) ASH PF15780.5 RLN02453.1 - 0.00031 20.9 0.0 0.0012 19.0 0.0 1.8 1 1 1 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 RLN02453.1 - 0.081 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 131-like Motile_Sperm PF00635.26 RLN02453.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 MSP (Major sperm protein) domain ASH PF15780.5 RLN02454.1 - 8.2e-22 77.3 11.2 0.0096 16.1 0.1 10.4 9 1 0 9 9 9 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 RLN02454.1 - 4.2e-06 26.6 3.3 3.4 7.6 0.0 6.0 8 0 0 8 8 8 2 MSP (Major sperm protein) domain MYCBPAP PF14646.6 RLN02454.1 - 0.0018 17.3 0.2 0.2 10.6 0.0 3.3 4 0 0 4 4 4 1 MYCBP-associated protein family Chlor_dismutase PF06778.12 RLN02454.1 - 0.19 11.3 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 Chlorite dismutase PX PF00787.24 RLN02455.1 - 0.0054 16.7 0.0 0.087 12.8 0.0 2.5 3 0 0 3 3 3 1 PX domain DNA_pol3_finger PF17657.1 RLN02458.1 - 0.07 12.5 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit finger domain UCH PF00443.29 RLN02460.1 - 1.9e-55 188.1 0.0 3.6e-55 187.2 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN02460.1 - 1.7e-12 47.6 0.0 4.8e-06 26.4 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase EF-hand_6 PF13405.6 RLN02460.1 - 0.11 12.5 0.2 0.29 11.2 0.2 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 RLN02460.1 - 0.12 12.9 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair PI3_PI4_kinase PF00454.27 RLN02461.1 - 5.9e-28 98.3 0.0 1.9e-20 73.7 0.0 2.3 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase GDP_Man_Dehyd PF16363.5 RLN02462.1 - 6.9e-48 163.8 0.0 1.3e-47 162.9 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RLN02462.1 - 2.6e-43 148.2 0.0 3.6e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 RLN02462.1 - 1.9e-07 30.6 0.1 0.0013 18.0 0.0 2.3 1 1 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 RLN02462.1 - 3.9e-07 29.3 0.0 6.2e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 RLN02462.1 - 2.2e-05 23.7 0.0 3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RLN02462.1 - 5e-05 22.6 0.0 0.2 10.8 0.0 2.4 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.25 RLN02462.1 - 0.0038 16.7 0.0 0.0063 16.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase UDPG_MGDP_dh_N PF03721.14 RLN02462.1 - 0.089 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1815 PF08844.10 RLN02462.1 - 0.091 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) KR PF08659.10 RLN02462.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 KR domain zf-CCHC_3 PF13917.6 RLN02463.1 - 0.00094 19.1 0.0 0.0036 17.2 0.0 2.0 1 0 0 1 1 1 1 Zinc knuckle CD52 PF15116.6 RLN02463.1 - 0.11 12.5 0.2 0.11 12.5 0.2 2.1 2 0 0 2 2 2 0 CAMPATH-1 antigen GREB1 PF15782.5 RLN02463.1 - 4.4 4.3 18.9 5.2 4.1 18.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PP2C PF00481.21 RLN02464.1 - 1.3e-68 231.4 0.0 1.7e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RLN02464.1 - 2.9e-06 27.1 0.0 7.4e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C MFS_2 PF13347.6 RLN02465.1 - 1.6e-12 46.7 8.5 1.6e-12 46.7 8.5 2.3 2 0 0 2 2 2 1 MFS/sugar transport protein RRM_1 PF00076.22 RLN02466.1 - 2.2e-06 27.4 0.1 3.8e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BT1 PF03092.16 RLN02470.1 - 1.3e-16 59.9 12.2 6.7e-13 47.7 0.5 3.3 3 0 0 3 3 3 3 BT1 family PUCC PF03209.15 RLN02470.1 - 0.12 11.4 13.0 2.7 6.9 13.0 2.4 1 1 0 1 1 1 0 PUCC protein Sugar_tr PF00083.24 RLN02471.1 - 3.8e-17 62.3 24.6 3.8e-17 62.3 24.6 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN02471.1 - 0.0015 17.5 27.2 0.0015 17.5 27.2 4.4 3 1 3 6 6 6 1 Major Facilitator Superfamily Glucan_synthase PF02364.15 RLN02471.1 - 0.0022 16.3 0.0 0.0041 15.4 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FAM176 PF14851.6 RLN02471.1 - 0.049 13.3 0.1 0.049 13.3 0.1 3.1 3 0 0 3 3 3 0 FAM176 family HAT_KAT11 PF08214.11 RLN02472.1 - 6e-26 91.6 9.7 1.4e-25 90.4 0.2 3.5 2 1 0 2 2 2 1 Histone acetylation protein zf-TAZ PF02135.16 RLN02472.1 - 8.5e-24 83.8 65.1 4.5e-11 43.1 15.5 5.5 6 1 0 6 6 6 3 TAZ zinc finger Bromodomain PF00439.25 RLN02472.1 - 6e-19 67.9 0.1 1.6e-18 66.5 0.1 1.7 1 0 0 1 1 1 1 Bromodomain ZZ PF00569.17 RLN02472.1 - 1.8e-07 30.8 5.7 1.8e-07 30.8 5.7 5.9 7 0 0 7 7 7 1 Zinc finger, ZZ type PHD PF00628.29 RLN02472.1 - 9.7e-06 25.4 3.4 9.7e-06 25.4 3.4 5.2 4 1 1 5 5 5 1 PHD-finger DUF902 PF06001.13 RLN02472.1 - 0.0053 17.2 3.6 0.013 16.0 3.6 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF902) SAPS PF04499.15 RLN02472.1 - 7.7 5.2 10.7 0.62 8.8 4.9 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein PX PF00787.24 RLN02473.1 - 2.6e-12 46.7 0.0 5e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 PX domain TMP-TENI PF02581.17 RLN02475.1 - 7.4e-40 136.2 0.0 1.6e-39 135.1 0.0 1.5 1 1 0 1 1 1 1 Thiamine monophosphate synthase AA_permease_2 PF13520.6 RLN02476.1 - 3.3e-44 151.4 36.3 4.3e-44 151.0 36.3 1.1 1 0 0 1 1 1 1 Amino acid permease DLH PF01738.18 RLN02477.1 - 1.9e-05 24.3 0.1 0.00024 20.7 0.1 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 RLN02477.1 - 0.00013 21.3 0.0 0.00024 20.4 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 RLN02477.1 - 0.00061 19.7 0.1 0.001 19.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF4050 PF13259.6 RLN02477.1 - 0.0051 17.2 1.1 0.063 13.6 0.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4050) LPP PF04728.13 RLN02478.1 - 0.13 12.7 0.2 0.13 12.7 0.2 7.3 7 2 1 8 8 8 0 Lipoprotein leucine-zipper Pur_ac_phosph_N PF16656.5 RLN02479.1 - 9.8e-19 67.7 0.1 2.9e-18 66.2 0.1 1.9 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 RLN02479.1 - 3.8e-13 50.1 0.2 1.2e-12 48.5 0.2 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 RLN02479.1 - 3.3e-11 44.1 4.6 5e-11 43.5 3.9 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Sec62 PF03839.16 RLN02480.1 - 2.4e-31 109.0 5.1 4.2e-31 108.2 5.1 1.3 1 0 0 1 1 1 1 Translocation protein Sec62 MgtE PF01769.16 RLN02480.1 - 0.32 11.4 7.6 0.61 10.5 7.6 1.4 1 0 0 1 1 1 0 Divalent cation transporter Cadherin_C_2 PF16492.5 RLN02480.1 - 2.1 9.1 4.2 8.8 7.2 4.2 2.1 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal DUF3810 PF12725.7 RLN02480.1 - 2.3 7.5 4.1 3.2 7.0 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Thioredoxin PF00085.20 RLN02481.1 - 2.3e-21 75.7 0.0 2.9e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 RLN02481.1 - 2.1e-05 24.0 0.0 2.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 RLN02481.1 - 6e-05 23.5 0.2 0.0016 18.8 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 RLN02481.1 - 0.00018 21.3 0.0 0.00023 20.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 RLN02481.1 - 0.00049 20.4 0.0 0.00069 19.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 RLN02481.1 - 0.00064 19.9 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin AhpC-TSA PF00578.21 RLN02481.1 - 0.0065 16.4 0.0 0.0095 15.8 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family TraF PF13728.6 RLN02481.1 - 0.0073 16.1 0.0 0.0091 15.8 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF1281_C PF18406.1 RLN02481.1 - 0.074 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Ferredoxin-like domain in Api92-like protein Redoxin PF08534.10 RLN02481.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.4 1 1 0 1 1 1 0 Redoxin SNF2_N PF00176.23 RLN02482.1 - 9.2e-62 208.8 0.1 2.3e-61 207.5 0.1 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN02482.1 - 1.2e-19 70.7 0.0 1.8e-18 66.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 RLN02482.1 - 4.5e-16 58.5 8.0 2.8e-08 33.5 0.2 3.1 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 RLN02482.1 - 1.6e-08 34.8 0.0 7e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 RLN02482.1 - 6e-05 22.3 0.2 0.00022 20.5 0.2 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 RLN02482.1 - 0.00043 20.1 0.0 0.0067 16.2 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 RLN02482.1 - 0.0041 16.8 0.0 0.03 14.0 0.0 2.2 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DUF3107 PF11305.8 RLN02482.1 - 0.09 13.0 1.1 5.5 7.3 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3107) APC_rep PF18797.1 RLN02483.1 - 0.034 15.1 0.5 0.18 12.8 0.5 2.2 1 0 0 1 1 1 0 Adenomatous polyposis coli (APC) repeat Rab5-bind PF09311.11 RLN02483.1 - 0.75 9.1 33.8 9.1 5.6 33.8 2.4 1 1 0 1 1 1 0 Rabaptin-like protein ATG16 PF08614.11 RLN02483.1 - 0.86 9.8 36.8 0.52 10.5 19.6 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4047 PF13256.6 RLN02483.1 - 2 8.6 12.9 5.7 7.2 3.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) V-SNARE PF05008.15 RLN02483.1 - 6.8 7.1 19.9 0.53 10.7 3.2 3.8 3 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus UbiA PF01040.18 RLN02484.1 - 2.4e-05 23.8 23.2 2.8e-05 23.5 20.1 1.9 1 1 1 2 2 2 2 UbiA prenyltransferase family AA_permease_2 PF13520.6 RLN02485.1 - 2.2e-41 142.1 38.0 3.2e-41 141.6 38.0 1.2 1 0 0 1 1 1 1 Amino acid permease Doppel PF11466.8 RLN02485.1 - 0.77 9.5 5.7 0.083 12.6 0.3 2.3 2 0 0 2 2 2 0 Prion-like protein Doppel RSN1_7TM PF02714.15 RLN02486.1 - 4.8e-40 137.6 18.9 9.4e-40 136.6 18.9 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 RLN02486.1 - 1.9e-27 95.9 1.3 1.9e-27 95.9 1.3 2.0 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 RLN02486.1 - 8.5e-27 94.5 0.2 1.4e-17 64.5 0.1 2.3 1 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter Peptidase_C48 PF02902.19 RLN02488.1 - 6e-07 29.5 0.0 1.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MULE PF10551.9 RLN02488.1 - 2.8e-05 24.5 0.0 0.00018 21.8 0.0 2.5 1 1 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 RLN02488.1 - 0.00072 19.2 0.3 0.0016 18.1 0.3 1.6 1 0 0 1 1 1 1 SWIM zinc finger Guanylate_cyc PF00211.20 RLN02489.1 - 1.4e-08 34.5 0.0 2.8e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF726 PF05277.12 RLN02492.1 - 3.3e-94 315.6 2.0 6.4e-72 242.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF726) ADIP PF11559.8 RLN02493.1 - 0.011 15.9 9.4 0.011 15.9 9.4 8.2 1 1 6 8 8 8 0 Afadin- and alpha -actinin-Binding CEP19 PF14933.6 RLN02494.1 - 2.5 8.4 11.4 1.9e+02 2.2 0.0 3.4 2 1 0 2 2 2 0 CEP19-like protein Frag1 PF10277.9 RLN02495.1 - 3.6e-13 49.6 2.3 4.6e-13 49.2 2.3 1.2 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family HemY_N PF07219.13 RLN02495.1 - 0.016 15.4 2.7 0.12 12.6 2.7 2.4 1 1 0 1 1 1 0 HemY protein N-terminus DUF973 PF06157.11 RLN02495.1 - 0.28 10.2 0.1 0.52 9.3 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF973) SPX PF03105.19 RLN02495.1 - 2.4 8.0 14.1 3.1 7.6 14.1 1.1 1 0 0 1 1 1 0 SPX domain KTI12 PF08433.10 RLN02496.1 - 3.4e-48 164.4 0.0 1.8e-26 93.2 0.0 2.1 1 1 1 2 2 2 2 Chromatin associated protein KTI12 DUF4743 PF15916.5 RLN02496.1 - 0.1 12.6 0.0 2.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4743) ODR4-like PF14778.6 RLN02496.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Olfactory receptor 4-like AAA_16 PF13191.6 RLN02497.1 - 8e-13 49.1 0.7 3.1e-11 44.0 0.7 2.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RLN02497.1 - 5.3e-05 23.5 4.0 0.019 15.2 0.0 3.6 4 0 0 4 4 4 2 AAA domain NACHT PF05729.12 RLN02497.1 - 0.00033 20.6 2.5 0.037 14.0 0.0 3.7 3 1 0 3 3 3 1 NACHT domain AAA_19 PF13245.6 RLN02497.1 - 0.037 14.4 0.0 0.12 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 RLN02497.1 - 0.038 13.1 2.6 0.086 12.0 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 ATPase PF06745.13 RLN02497.1 - 0.044 13.1 0.1 7.4 5.8 0.0 3.2 3 0 0 3 3 3 0 KaiC Roc PF08477.13 RLN02497.1 - 0.045 14.0 1.1 1.6 8.9 0.0 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 RLN02497.1 - 0.2 12.1 4.0 3.9 7.9 0.0 3.8 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) ARL2_Bind_BART PF11527.8 RLN02498.1 - 1.3e-20 73.6 0.2 1.3e-20 73.6 0.2 2.4 3 0 0 3 3 3 1 The ARF-like 2 binding protein BART WW PF00397.26 RLN02498.1 - 2.6e-06 27.4 3.9 5.4e-06 26.4 3.9 1.5 1 0 0 1 1 1 1 WW domain U79_P34 PF03064.16 RLN02498.1 - 0.0051 16.2 2.1 0.0094 15.3 2.1 1.4 1 0 0 1 1 1 1 HSV U79 / HCMV P34 DUF2605 PF10792.9 RLN02499.1 - 0.0006 19.7 0.1 0.0016 18.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2605) F-box-like PF12937.7 RLN02499.1 - 0.018 14.9 0.4 0.073 13.0 0.2 2.2 2 0 0 2 2 2 0 F-box-like ABM PF03992.16 RLN02536.1 - 0.029 14.5 0.3 0.045 13.9 0.3 1.3 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase MbeD_MobD PF04899.12 RLN02537.1 - 0.00033 20.7 0.8 0.0041 17.2 1.1 2.2 2 0 0 2 2 2 1 MbeD/MobD like Aminotran_3 PF00202.21 RLN02538.1 - 5.3e-122 407.4 0.1 6.5e-122 407.1 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III PPPI_inhib PF14895.6 RLN02539.1 - 0.025 13.8 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 1 inhibitor Kinesin PF00225.23 RLN02540.1 - 9.6e-90 300.9 0.1 1.7e-89 300.1 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN02540.1 - 1.8e-33 115.6 0.0 7.9e-33 113.5 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding Taxilin PF09728.9 RLN02540.1 - 0.00049 19.4 11.0 0.001 18.3 11.0 1.5 1 0 0 1 1 1 1 Myosin-like coiled-coil protein YabA PF06156.13 RLN02540.1 - 7.4 7.3 14.2 21 5.9 1.3 4.4 3 1 1 4 4 4 0 Initiation control protein YabA Pep3_Vps18 PF05131.14 RLN02542.1 - 6.3e-41 139.7 0.0 1.9e-40 138.1 0.0 1.9 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 RLN02542.1 - 1.2e-13 51.1 5.7 2.3e-09 37.2 0.2 3.5 4 0 0 4 4 4 2 Region in Clathrin and VPS zf-RING_11 PF17123.5 RLN02542.1 - 0.053 13.3 0.2 0.14 11.9 0.2 1.7 1 0 0 1 1 1 0 RING-like zinc finger Vps39_2 PF10367.9 RLN02542.1 - 0.14 12.6 0.2 1.9 8.9 0.2 2.7 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Etmic-2 PF06670.11 RLN02542.1 - 0.15 11.0 0.3 0.3 10.0 0.3 1.4 1 0 0 1 1 1 0 Microneme protein Etmic-2 Herpes_U26 PF07402.11 RLN02542.1 - 0.23 11.0 0.2 0.38 10.3 0.2 1.2 1 0 0 1 1 1 0 Human herpesvirus U26 protein GrpE PF01025.19 RLN02542.1 - 0.59 9.8 5.0 6.4 6.4 0.3 2.4 2 0 0 2 2 2 0 GrpE Utp12 PF04003.12 RLN02542.1 - 0.66 10.3 3.3 0.52 10.7 0.4 2.1 2 0 0 2 2 2 0 Dip2/Utp12 Family TPR_MLP1_2 PF07926.12 RLN02542.1 - 1.6 8.8 11.3 1.8 8.6 0.8 3.1 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF5626 PF18540.1 RLN02543.1 - 0.04 14.4 2.0 11 6.6 0.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5626) DUF108 PF01958.18 RLN02543.1 - 0.25 11.7 1.8 3.5 8.1 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF108 Y_phosphatase PF00102.27 RLN02555.1 - 6.1e-08 32.5 0.0 8e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 RLN02555.1 - 2.8e-06 27.2 0.0 3.5e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RLN02555.1 - 0.00028 21.1 0.0 0.00036 20.7 0.0 1.1 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 RLN02555.1 - 0.00048 19.8 0.0 0.00079 19.1 0.0 1.4 1 1 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF1623 PF07785.11 RLN02555.1 - 0.023 14.9 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1623) Mid2 PF04478.12 RLN02555.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor HABP4_PAI-RBP1 PF04774.15 RLN02556.1 - 0.00073 20.4 1.9 0.00082 20.2 1.9 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family Ank_4 PF13637.6 RLN02557.1 - 1.5e-15 57.4 4.0 1.6e-06 28.5 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN02557.1 - 1.3e-10 41.3 4.8 0.0036 17.6 0.1 5.1 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN02557.1 - 4.7e-10 39.9 0.3 0.0001 22.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN02557.1 - 9.9e-06 25.5 0.8 9.2 7.2 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 RLN02558.1 - 1.6e-17 63.6 3.7 1.1e-05 25.9 0.1 3.9 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN02558.1 - 6e-15 55.6 0.0 1e-05 26.0 0.0 2.9 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN02558.1 - 2.3e-10 40.5 0.4 0.031 14.6 0.1 5.0 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN02558.1 - 0.00023 21.3 0.0 73 4.4 0.0 5.1 5 1 1 6 6 6 0 Ankyrin repeat Nup54 PF13874.6 RLN02558.1 - 0.17 12.0 0.0 0.37 10.9 0.0 1.5 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Ank_2 PF12796.7 RLN02559.1 - 1.7e-08 35.0 2.2 0.0075 16.8 0.3 3.3 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN02559.1 - 7e-06 26.5 4.8 6.9 7.4 0.0 5.7 4 2 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN02559.1 - 0.0028 18.0 3.7 11 6.9 0.0 5.5 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 RLN02559.1 - 0.029 14.7 7.0 18 5.8 0.4 4.6 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Ank PF00023.30 RLN02559.1 - 0.03 14.8 1.4 15 6.3 0.4 4.3 3 2 0 3 3 3 0 Ankyrin repeat SNF2_N PF00176.23 RLN02560.1 - 2.6e-58 197.4 0.0 5.1e-58 196.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF155 PF02582.14 RLN02560.1 - 7.6e-40 136.9 0.1 1.2e-39 136.2 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Helicase_C PF00271.31 RLN02560.1 - 1e-17 64.4 0.0 2.4e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN02560.1 - 2.1e-07 31.1 0.0 4.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 RLN02560.1 - 0.0038 16.9 0.0 0.0077 15.9 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase GEMIN8 PF15348.6 RLN02560.1 - 0.56 10.5 5.1 1.5 9.1 5.1 1.6 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 GCD14 PF08704.10 RLN02561.1 - 4.1e-78 262.5 0.1 6.3e-77 258.6 0.1 2.2 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 RLN02561.1 - 1e-08 35.1 0.0 1.7e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN02561.1 - 5.1e-07 30.3 0.1 2e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN02561.1 - 3.4e-06 27.6 0.0 1.1e-05 26.0 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 RLN02561.1 - 8.3e-06 26.8 0.0 2.3e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 RLN02561.1 - 3.5e-05 23.7 0.0 5.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 RLN02561.1 - 0.00023 20.6 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 RLN02561.1 - 0.00047 20.0 0.0 0.0022 17.8 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.17 RLN02561.1 - 0.0041 16.3 0.0 0.0066 15.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase GCD14_N PF14801.6 RLN02561.1 - 0.012 15.4 0.0 0.039 13.8 0.0 1.9 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term Methyltr_RsmB-F PF01189.17 RLN02561.1 - 0.013 15.1 0.0 0.1 12.2 0.0 2.0 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F Methyltransf_12 PF08242.12 RLN02561.1 - 0.023 15.4 0.0 0.09 13.5 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain DUF4834 PF16118.5 RLN02561.1 - 0.043 14.8 0.1 0.073 14.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Fibrillarin PF01269.17 RLN02561.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Glyco_transf_20 PF00982.21 RLN02569.1 - 3.3e-123 411.8 0.0 2.7e-122 408.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 RLN02569.1 - 8.2e-12 44.7 0.0 1.5e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase DegS PF05384.11 RLN02569.1 - 0.13 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Sensor protein DegS Solute_trans_a PF03619.16 RLN02609.1 - 3.7e-85 285.7 17.0 4.4e-85 285.4 17.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha YL1 PF05764.13 RLN02609.1 - 0.013 15.6 9.3 0.019 15.1 9.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 RLN02609.1 - 0.18 10.0 9.8 0.25 9.6 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein MFMR_assoc PF16596.5 RLN02609.1 - 1.1 9.8 8.6 1.9 8.9 8.6 1.4 1 0 0 1 1 1 0 Disordered region downstream of MFMR PDZ_6 PF17820.1 RLN02610.1 - 5e-06 26.3 0.0 0.026 14.4 0.0 3.5 3 0 0 3 3 3 1 PDZ domain PDZ PF00595.24 RLN02610.1 - 7.4e-05 23.0 0.0 13 6.2 0.0 4.5 5 0 0 5 5 5 3 PDZ domain SprA-related PF12118.8 RLN02610.1 - 0.04 13.1 13.4 0.067 12.3 13.4 1.2 1 0 0 1 1 1 0 SprA-related family TFIIA PF03153.13 RLN02610.1 - 8.7 6.2 12.2 12 5.7 12.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF948 PF06103.11 RLN02611.1 - 0.074 13.3 0.4 0.22 11.8 0.2 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Thump_like PF18096.1 RLN02612.1 - 0.047 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 THUMP domain-like Noggin PF05806.12 RLN02612.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Noggin DAGAT PF03982.13 RLN02613.1 - 2.6e-34 118.5 0.0 5.3e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 RLN02613.1 - 0.073 12.7 0.1 1.2 8.7 0.0 2.3 1 1 1 2 2 2 0 Acyltransferase Pkinase_Tyr PF07714.17 RLN02616.1 - 4.8e-35 121.1 0.0 8.1e-27 94.1 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN02616.1 - 2.2e-29 102.6 0.6 3.7e-22 79.0 0.0 3.2 3 1 1 4 4 4 2 Protein kinase domain Spec3 PF15795.5 RLN02616.1 - 0.021 15.3 0.1 0.045 14.3 0.1 1.5 1 0 0 1 1 1 0 Ectodermal ciliogenesis protein NAP PF00956.18 RLN02616.1 - 0.066 12.4 3.2 0.14 11.3 2.2 1.9 2 0 0 2 2 2 0 Nucleosome assembly protein (NAP) APH PF01636.23 RLN02616.1 - 0.08 12.9 2.2 0.31 10.9 0.0 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family Viral_env_E26 PF11050.8 RLN02616.1 - 1.9 7.8 4.2 8.6 5.7 0.3 2.3 2 0 0 2 2 2 0 Virus envelope protein E26 Pkinase_Tyr PF07714.17 RLN02617.1 - 2.3e-42 145.1 0.0 3.3e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN02617.1 - 2e-37 129.0 0.0 3.1e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DZR PF12773.7 RLN02617.1 - 0.0005 20.0 0.6 0.0013 18.7 0.6 1.6 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 RLN02617.1 - 0.00052 20.7 0.8 0.0011 19.6 0.8 1.6 1 0 0 1 1 1 1 zinc-ribbon family UPF0547 PF10571.9 RLN02617.1 - 0.024 14.7 3.3 0.055 13.5 3.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 APH PF01636.23 RLN02617.1 - 0.028 14.3 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 RLN02617.1 - 0.076 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 RIO1 family ABC1 PF03109.16 RLN02617.1 - 0.088 13.0 0.0 0.67 10.1 0.0 2.2 2 0 0 2 2 2 0 ABC1 family zf-NADH-PPase PF09297.11 RLN02617.1 - 0.12 12.0 5.8 4.3 7.1 0.1 2.9 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Kdo PF06293.14 RLN02617.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zinc_ribbon_2 PF13240.6 RLN02617.1 - 0.85 9.4 6.3 6.7 6.6 6.5 2.4 1 1 1 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 RLN02617.1 - 1.5 8.3 9.1 0.4 10.2 3.8 2.6 2 1 0 2 2 2 0 zinc-ribbon domain Glyco_hydro_7 PF00840.20 RLN02618.1 - 2.8e-37 128.5 0.0 3.1e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Glyco_hydro_7 PF00840.20 RLN02619.1 - 6.4e-147 489.8 14.8 7.3e-147 489.6 14.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 OrfB_Zn_ribbon PF07282.11 RLN02619.1 - 0.54 10.2 3.6 0.73 9.8 0.1 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain CXCR4_N PF12109.8 RLN02619.1 - 1.8 8.8 6.3 6 7.2 6.3 1.9 1 0 0 1 1 1 0 CXCR4 Chemokine receptor N terminal Pkinase PF00069.25 RLN02620.1 - 2.5e-59 200.8 0.0 1.2e-38 133.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN02620.1 - 6.4e-31 107.6 0.0 8.2e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN02620.1 - 3.4e-05 23.9 0.0 0.046 13.6 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN02620.1 - 0.047 12.5 0.1 0.072 11.9 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 RLN02621.1 - 5.4e-60 203.0 0.0 5.6e-39 134.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN02621.1 - 2.7e-34 118.6 0.0 6.6e-34 117.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN02621.1 - 0.0029 16.4 1.9 0.0073 15.1 1.8 1.5 1 1 0 1 1 1 1 Fungal protein kinase CDC45 PF02724.14 RLN02621.1 - 0.087 11.1 5.9 0.12 10.7 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 RLN02621.1 - 0.63 8.6 9.0 0.9 8.1 9.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Hid1 PF12722.7 RLN02621.1 - 0.76 7.8 2.6 0.99 7.5 2.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PTPRCAP PF15713.5 RLN02621.1 - 1.4 9.2 9.3 2.7 8.3 9.3 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated PLDc_2 PF13091.6 RLN02623.1 - 2.6e-15 56.5 0.0 2.2e-08 34.1 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 RLN02623.1 - 0.0053 16.9 3.5 0.14 12.4 0.1 3.2 3 0 0 3 3 3 1 Phospholipase D Active site motif TetR_C_31 PF17940.1 RLN02623.1 - 0.14 12.4 2.1 0.61 10.3 0.2 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain VWA_3 PF13768.6 RLN02623.1 - 0.14 12.1 0.0 2.6 8.0 0.0 2.4 2 0 0 2 2 2 0 von Willebrand factor type A domain CTP_transf_1 PF01148.20 RLN02624.1 - 0.042 13.6 4.4 0.042 13.6 2.2 2.1 1 1 1 2 2 2 0 Cytidylyltransferase family DUF3382 PF11862.8 RLN02624.1 - 0.054 13.8 2.0 0.11 12.8 0.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) Aconitase_C PF00694.19 RLN02639.1 - 2.6e-23 82.8 0.0 3.5e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Aconitase C-terminal domain Aa_trans PF01490.18 RLN02641.1 - 2.1e-08 33.3 2.3 2.5e-08 33.1 2.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 RLN02641.1 - 0.00049 19.2 1.5 0.00061 18.9 1.5 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DUF3018 PF11455.8 RLN02642.1 - 0.029 14.3 0.0 0.11 12.4 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3018) Pkinase PF00069.25 RLN02643.1 - 1.2e-51 175.6 0.2 1.7e-46 158.7 0.1 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN02643.1 - 3.7e-23 82.1 0.1 4.5e-23 81.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN02643.1 - 2.4e-07 29.9 0.1 5.8e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 RLN02643.1 - 5e-06 26.0 0.1 7.4e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN02643.1 - 0.0032 17.4 0.0 1.1 9.1 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 RLN02643.1 - 0.0049 16.5 0.1 0.0072 15.9 0.1 1.2 1 0 0 1 1 1 1 RIO1 family DUF1336 PF07059.12 RLN02661.1 - 3.6e-68 230.1 0.0 5.2e-68 229.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) START PF01852.19 RLN02661.1 - 9.4e-21 74.2 0.2 2.1e-20 73.0 0.2 1.5 1 0 0 1 1 1 1 START domain PH PF00169.29 RLN02661.1 - 1e-09 38.8 0.0 2.8e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN02661.1 - 0.00077 19.7 0.1 0.13 12.5 0.0 2.8 3 0 0 3 3 3 1 Pleckstrin homology domain Polyketide_cyc2 PF10604.9 RLN02661.1 - 0.032 14.5 0.1 0.086 13.1 0.1 1.7 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport PH_11 PF15413.6 RLN02661.1 - 0.036 14.5 1.2 0.25 11.8 1.2 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain OST3_OST6 PF04756.13 RLN02662.1 - 1.7e-73 247.6 0.1 2.2e-73 247.2 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 RLN02662.1 - 0.003 17.5 0.0 0.0078 16.2 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin DUF1350 PF07082.11 RLN02662.1 - 0.041 13.2 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) LEAP-2 PF07359.11 RLN02662.1 - 0.22 11.3 2.4 0.86 9.5 0.1 2.6 3 0 0 3 3 3 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) OATP PF03137.20 RLN02662.1 - 0.59 8.4 4.9 0.077 11.3 0.7 1.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SHIPPO-rpt PF07004.12 RLN02663.1 - 5.1e-08 33.5 20.5 0.24 12.4 1.2 7.8 7 0 0 7 7 7 4 Sperm-tail PG-rich repeat Cyclin_N PF00134.23 RLN02663.1 - 1e-06 28.5 0.4 1.9e-06 27.6 0.4 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TCR PF03638.15 RLN02664.1 - 4e-25 87.8 51.8 1.3e-12 47.8 20.4 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain F-box-like PF12937.7 RLN02664.1 - 7.5e-05 22.5 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RLN02664.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 F-box domain Pox_Ag35 PF03286.14 RLN02664.1 - 4.7 6.9 13.9 2 8.2 0.2 2.9 2 0 0 2 2 2 0 Pox virus Ag35 surface protein His_Phos_2 PF00328.22 RLN02665.1 - 1.3e-15 57.7 0.1 5e-11 42.6 0.1 2.7 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Herpes_UL95 PF03038.14 RLN02665.1 - 0.14 11.3 0.4 0.29 10.2 0.3 1.5 1 1 0 1 1 1 0 UL95 family PARP_reg PF02877.14 RLN02666.1 - 3e-46 156.9 2.1 7.8e-25 87.5 0.1 2.5 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase, regulatory domain PARP PF00644.20 RLN02666.1 - 1.7e-40 138.7 0.3 4.5e-23 81.8 0.0 4.4 3 2 2 5 5 5 3 Poly(ADP-ribose) polymerase catalytic domain WGR PF05406.15 RLN02666.1 - 3e-32 110.5 7.2 9.2e-17 60.9 0.1 3.1 3 0 0 3 3 3 2 WGR domain Baculo_PP31 PF05311.11 RLN02666.1 - 0.015 14.8 3.6 0.28 10.6 1.0 2.7 2 1 1 3 3 3 0 Baculovirus 33KDa late protein (PP31) Not3 PF04065.15 RLN02666.1 - 1.2 8.5 7.0 0.22 10.9 0.3 2.8 3 0 0 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component Rubis-subs-bind PF09273.11 RLN02667.1 - 1.3e-14 55.0 0.0 2.4e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 RLN02667.1 - 2.6e-05 24.7 0.0 6.7e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 SET domain GMC_oxred_C PF05199.13 RLN02672.1 - 6.1e-40 137.1 0.1 7.8e-40 136.7 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 RLN02673.1 - 2.2e-23 83.1 1.0 2.8e-23 82.7 1.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Prominin PF05478.11 RLN02674.1 - 0.024 12.6 4.1 0.045 11.7 4.1 1.3 1 0 0 1 1 1 0 Prominin Peptidase_M2 PF01401.18 RLN02674.1 - 0.036 12.7 1.9 0.061 11.9 1.9 1.2 1 0 0 1 1 1 0 Angiotensin-converting enzyme TINF2_N PF14973.6 RLN02674.1 - 0.043 14.2 2.1 0.16 12.3 2.1 2.0 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus Spc7 PF08317.11 RLN02674.1 - 0.18 10.6 11.9 0.035 13.0 7.4 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein ATP-synt_D PF01813.17 RLN02674.1 - 0.56 10.0 8.4 2.6 7.9 2.4 2.7 2 0 0 2 2 2 0 ATP synthase subunit D DUF2730 PF10805.8 RLN02674.1 - 1.2 9.2 9.7 22 5.2 0.2 4.7 3 2 2 5 5 5 0 Protein of unknown function (DUF2730) FUSC PF04632.12 RLN02674.1 - 1.2 7.5 26.4 0.91 8.0 15.4 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family Seryl_tRNA_N PF02403.22 RLN02674.1 - 1.3 9.3 8.0 30 4.9 4.4 3.1 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GCP_N_terminal PF17681.1 RLN02674.1 - 1.9 8.1 4.7 1.2 8.7 2.7 1.6 2 0 0 2 2 2 0 Gamma tubulin complex component N-terminal Fez1 PF06818.15 RLN02674.1 - 2 8.8 14.9 0.052 14.0 6.2 2.4 2 1 0 2 2 2 0 Fez1 BLOC1_2 PF10046.9 RLN02674.1 - 4.3 7.7 12.2 2 8.7 0.6 4.3 4 1 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1690 PF07956.11 RLN02674.1 - 4.6 7.7 12.0 1.7 9.0 0.0 3.9 3 1 1 4 4 4 0 Protein of Unknown function (DUF1690) Cellulase PF00150.18 RLN02675.1 - 2.8e-28 99.2 0.4 3.4e-28 98.9 0.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Peptidase_M20 PF01546.28 RLN02676.1 - 2e-26 93.0 0.0 3.1e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 RLN02676.1 - 3.2e-09 36.7 0.0 6.2e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 RLN02676.1 - 0.026 14.2 0.0 3 7.5 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M28 Dymeclin PF09742.9 RLN02684.1 - 0.00034 19.2 0.4 0.0005 18.6 0.4 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein zf-RanBP PF00641.18 RLN02684.1 - 0.00047 19.4 9.8 0.037 13.4 5.2 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 RLN02684.1 - 0.019 15.0 4.3 0.034 14.2 4.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.15 RLN02684.1 - 0.053 13.6 8.6 0.091 12.8 3.6 2.9 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 RLN02684.1 - 0.1 12.0 8.1 1.1 8.7 3.2 2.8 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain B-block_TFIIIC PF04182.12 RLN02685.1 - 5.8e-10 39.2 0.0 4.6e-09 36.3 0.0 2.6 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC RRP7 PF12923.7 RLN02685.1 - 7.7 6.7 7.3 0.2 11.8 0.2 2.0 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF3437 PF11919.8 RLN02686.1 - 3.2e-27 94.3 0.1 9.2e-27 92.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) SDA1 PF05285.12 RLN02687.1 - 4e-49 167.9 40.6 3.2e-31 109.0 8.3 3.0 2 1 1 3 3 3 2 SDA1 NUC130_3NT PF08158.12 RLN02687.1 - 7e-21 74.3 0.4 2.1e-20 72.8 0.4 1.9 1 0 0 1 1 1 1 NUC130/3NT domain LOH1CR12 PF10158.9 RLN02687.1 - 1.1 9.3 6.4 4.5 7.3 0.9 2.8 2 0 0 2 2 2 0 Tumour suppressor protein LSM PF01423.22 RLN02688.1 - 9.9e-20 70.0 0.2 1.2e-19 69.7 0.2 1.1 1 0 0 1 1 1 1 LSM domain Methyltransf_16 PF10294.9 RLN02689.1 - 3.7e-16 59.4 0.0 5.5e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 RLN02689.1 - 0.048 13.0 0.1 0.1 12.0 0.1 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 RLN02689.1 - 0.088 12.4 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.15 RLN02689.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Pex2_Pex12 PF04757.14 RLN02690.1 - 1e-14 54.7 1.8 4.6e-14 52.6 1.8 1.9 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 RLN02690.1 - 1.7e-08 34.2 9.9 3.2e-08 33.3 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN02690.1 - 2.5e-08 34.1 11.2 2.5e-08 34.1 11.2 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 RLN02690.1 - 3e-08 33.4 9.0 6.1e-08 32.4 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN02690.1 - 7.2e-08 32.1 10.4 1.4e-07 31.2 10.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN02690.1 - 3.8e-07 29.9 10.6 7.1e-07 29.0 10.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN02690.1 - 3.6e-05 23.6 9.0 7.6e-05 22.6 9.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 RLN02690.1 - 4.6e-05 23.6 7.4 4.6e-05 23.6 7.4 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RLN02690.1 - 4.9e-05 23.3 10.4 0.00032 20.7 10.6 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 RLN02690.1 - 0.00016 21.8 10.6 0.00016 21.8 10.6 2.0 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 RLN02690.1 - 0.0089 16.1 3.6 0.0089 16.1 3.6 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 RLN02690.1 - 0.51 10.2 10.0 1.1 9.1 10.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Sas10_Utp3 PF04000.15 RLN02691.1 - 3.8e-08 33.8 0.0 1.2e-07 32.2 0.0 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Trypsin_2 PF13365.6 RLN02691.1 - 6.8e-08 33.5 0.1 3.7e-07 31.2 0.0 2.3 2 0 0 2 2 2 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.13 RLN02691.1 - 0.065 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 zf-RING_2 PF13639.6 RLN02699.1 - 1.4e-09 38.1 9.6 5.4e-08 33.0 9.6 2.9 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RLN02699.1 - 1.7e-07 31.4 7.1 5.6e-07 29.8 7.1 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 RLN02699.1 - 3e-06 26.9 1.3 3e-06 26.9 1.3 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN02699.1 - 6.2e-06 25.9 8.2 3.8e-05 23.4 0.3 3.3 3 0 0 3 3 3 2 RING-like zinc finger Prok-RING_4 PF14447.6 RLN02699.1 - 8.9e-06 25.5 2.7 3.4e-05 23.6 2.7 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 RLN02699.1 - 3.1e-05 23.8 3.9 0.00015 21.5 3.9 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN02699.1 - 4.8e-05 23.3 2.6 7.1e-05 22.8 1.1 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RLN02699.1 - 0.00033 20.4 6.9 0.011 15.5 6.9 2.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 RLN02699.1 - 0.00062 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 PX domain zf-ANAPC11 PF12861.7 RLN02699.1 - 0.00095 19.2 2.3 0.00095 19.2 2.3 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 RLN02699.1 - 0.0019 18.2 7.0 0.01 15.8 7.1 2.3 1 1 0 1 1 1 1 zinc-RING finger domain PP2C PF00481.21 RLN02700.1 - 1.3e-38 133.2 0.0 2.4e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.25 RLN02700.1 - 1.2e-34 119.9 0.0 2.1e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 RLN02700.1 - 1.5e-31 108.3 0.0 1.6e-14 53.7 0.0 3.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 RLN02700.1 - 9.2e-13 48.1 0.0 1.8e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN02700.1 - 1.7e-08 34.1 0.0 3.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PP2C_2 PF13672.6 RLN02700.1 - 5.6e-06 26.1 0.0 1.4e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Protein phosphatase 2C Cdh1_DBD_1 PF18196.1 RLN02701.1 - 0.28 11.5 2.1 0.34 11.2 2.1 1.0 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 ANAPC_CDC26 PF10471.9 RLN02701.1 - 0.38 11.6 8.8 0.93 10.4 8.8 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Sugar_tr PF00083.24 RLN02702.1 - 2.6e-80 270.5 19.4 1.5e-65 221.8 10.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RLN02702.1 - 8.6e-16 57.8 60.3 2.8e-08 33.1 20.1 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_3 PF05977.13 RLN02702.1 - 0.043 12.2 10.8 0.64 8.3 0.6 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector DUF2583 PF10762.9 RLN02702.1 - 8.5 6.9 10.3 1 9.8 4.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) WD40 PF00400.32 RLN02703.1 - 2e-05 25.3 0.2 2.2 9.3 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Glyco_hydro_47 PF01532.20 RLN02704.1 - 6.2e-111 371.5 0.0 4.1e-110 368.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 PA PF02225.22 RLN02704.1 - 5.4e-12 45.6 0.2 1.2e-11 44.4 0.2 1.6 1 0 0 1 1 1 1 PA domain MULE PF10551.9 RLN02727.1 - 0.022 15.1 0.1 0.29 11.6 0.0 2.7 3 0 0 3 3 3 0 MULE transposase domain Homoserine_dh PF00742.19 RLN02728.1 - 2.8e-38 131.5 0.0 6e-38 130.5 0.0 1.6 2 0 0 2 2 2 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 RLN02728.1 - 8.1e-07 29.7 0.0 3e-06 27.9 0.0 2.1 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 RLN02728.1 - 0.053 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ephrin_rec_like PF07699.13 RLN02730.1 - 6.6e-07 29.0 54.3 0.0011 18.7 0.5 8.4 6 3 3 9 9 9 7 Putative ephrin-receptor like DUF4215 PF13948.6 RLN02730.1 - 0.24 11.9 5.3 1.5 9.3 3.3 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4215) NCD3G PF07562.14 RLN02730.1 - 0.85 9.6 40.4 0.27 11.2 2.0 7.1 7 2 1 8 8 8 0 Nine Cysteines Domain of family 3 GPCR Pkinase PF00069.25 RLN02731.1 - 3.2e-31 108.6 0.0 2.7e-19 69.6 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN02731.1 - 1e-15 57.7 0.0 4.7e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 RLN02731.1 - 0.077 12.9 0.2 0.38 10.6 0.1 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Rdx PF10262.9 RLN02732.1 - 1.1e-27 96.0 0.0 1.5e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Rdx family Haem_degrading PF03928.14 RLN02732.1 - 0.13 12.4 0.1 1.7 8.7 0.1 2.0 1 1 0 2 2 2 0 Haem-degrading MLTD_N PF06474.12 RLN02734.1 - 9.6 6.5 8.7 0.33 11.2 0.4 2.9 3 0 0 3 3 3 0 MltD lipid attachment motif TPR_12 PF13424.6 RLN02735.1 - 0.00024 21.3 5.1 0.66 10.3 0.8 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat CopC PF04234.12 RLN02735.1 - 0.15 13.1 0.3 1.8 9.6 0.0 2.7 2 1 1 3 3 3 0 CopC domain Flg_hook PF02120.16 RLN02737.1 - 0.076 12.9 0.4 0.13 12.1 0.4 1.4 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK MFS_1 PF07690.16 RLN02767.1 - 5.7e-20 71.5 38.1 1.3e-18 67.0 23.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Microtub_bd PF16796.5 RLN02767.1 - 4.2e-08 33.2 0.4 1.3e-07 31.7 0.2 2.0 2 0 0 2 2 2 1 Microtubule binding MFS_1 PF07690.16 RLN02768.1 - 4.6e-19 68.6 29.8 7.2e-19 67.9 29.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TFIIF_alpha PF05793.12 RLN02769.1 - 0.31 9.6 8.3 0.36 9.4 8.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAM220 PF15487.6 RLN02769.1 - 0.75 9.4 5.7 0.95 9.0 5.7 1.1 1 0 0 1 1 1 0 FAM220 family TMEM171 PF15471.6 RLN02769.1 - 0.82 8.6 4.3 0.59 9.1 3.3 1.3 1 1 0 1 1 1 0 Transmembrane protein family 171 COesterase PF00135.28 RLN02770.1 - 3.9e-60 204.2 1.3 8e-60 203.2 1.3 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RLN02770.1 - 0.013 15.4 0.2 0.093 12.6 0.2 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF456 PF04306.13 RLN02771.1 - 0.067 13.5 1.6 0.14 12.4 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF456) N1221 PF07923.13 RLN02775.1 - 0.00022 20.5 0.1 0.00025 20.4 0.1 1.1 1 0 0 1 1 1 1 N1221-like protein DUF4855 PF16147.5 RLN02776.1 - 0.079 12.0 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4855) Abhydrolase_1 PF00561.20 RLN02778.1 - 0.0042 16.8 0.6 0.04 13.6 0.1 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 RLN02778.1 - 0.022 14.6 0.0 0.051 13.4 0.0 1.5 1 1 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 RLN02778.1 - 0.046 14.3 3.8 0.088 13.4 3.8 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family LCAT PF02450.15 RLN02778.1 - 0.047 12.9 0.0 0.088 12.0 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 RLN02778.1 - 0.056 12.8 0.1 1.6 8.0 0.1 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 RLN02778.1 - 0.061 13.0 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 RLN02778.1 - 0.1 12.1 0.0 0.7 9.4 0.0 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF900 PF05990.12 RLN02778.1 - 0.11 12.0 0.0 0.34 10.4 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Palm_thioest PF02089.15 RLN02779.1 - 0.0046 16.8 0.0 0.0067 16.3 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 RLN02779.1 - 0.0058 16.3 0.1 0.015 15.0 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 RLN02779.1 - 0.01 15.5 0.8 0.026 14.2 0.8 1.7 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 RLN02779.1 - 0.024 15.2 0.4 0.049 14.2 0.4 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.12 RLN02779.1 - 0.032 13.8 0.0 0.1 12.1 0.1 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 RLN02779.1 - 0.09 12.3 0.0 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) LCAT PF02450.15 RLN02779.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Orn_Arg_deC_N PF02784.16 RLN02780.1 - 1.1e-77 260.8 0.0 1.4e-77 260.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 RLN02780.1 - 1.3e-17 63.8 0.0 1.9e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain B12-binding PF02310.19 RLN02780.1 - 0.0052 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain Mannosyl_trans3 PF11051.8 RLN02781.1 - 2e-31 109.3 0.0 2.7e-30 105.7 0.0 2.1 1 1 0 1 1 1 1 Mannosyltransferase putative Ank_2 PF12796.7 RLN02786.1 - 2.5e-40 136.9 0.5 2.2e-09 37.8 0.0 6.7 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN02786.1 - 4.7e-37 125.9 10.7 1.5e-07 31.9 0.0 8.9 7 4 3 10 10 10 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN02786.1 - 5.6e-33 112.6 10.7 8.9e-05 22.7 0.0 13.5 5 2 10 15 15 15 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN02786.1 - 1.1e-25 86.9 3.7 1.4 9.7 0.0 14.3 13 3 3 16 16 16 6 Ankyrin repeat DUF5049 PF16468.5 RLN02786.1 - 8e-09 35.3 0.0 2.6 8.0 0.0 7.9 5 2 3 8 8 8 2 Domain of unknown function (DUF5049) Ank PF00023.30 RLN02786.1 - 1.6e-05 25.1 0.0 41 4.9 0.1 7.9 4 1 2 6 6 6 0 Ankyrin repeat DUF3322 PF11795.8 RLN02786.1 - 9e-05 22.6 4.2 0.13 12.3 0.0 5.0 4 1 2 6 6 6 2 Uncharacterized protein conserved in bacteria N-term (DUF3322) DUF4287 PF14117.6 RLN02786.1 - 1.8 8.8 16.7 5.7 7.1 0.4 6.7 8 1 1 9 9 9 0 Domain of unknown function (DUF4287) Mitofilin PF09731.9 RLN02791.1 - 0.11 11.3 5.4 0.13 11.1 5.4 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4813 PF16072.5 RLN02791.1 - 0.3 10.7 21.7 0.38 10.4 21.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) EamA PF00892.20 RLN02795.1 - 1.2e-11 45.0 8.3 1.2e-11 45.0 8.3 2.5 2 1 0 2 2 2 1 EamA-like transporter family TPT PF03151.16 RLN02795.1 - 0.0013 18.1 5.5 0.002 17.5 5.5 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 RLN02795.1 - 0.0028 16.9 1.0 0.0047 16.2 1.0 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 RLN02796.1 - 1.8e-12 47.6 21.2 4.6e-12 46.3 5.8 2.2 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 RLN02796.1 - 0.00079 18.7 2.6 0.0014 17.8 2.6 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter SLC35F PF06027.12 RLN02796.1 - 0.042 13.4 5.7 0.055 13.0 5.7 1.3 1 0 0 1 1 1 0 Solute carrier family 35 EamA PF00892.20 RLN02797.1 - 1.8e-12 47.6 4.6 1.8e-12 47.6 4.6 3.4 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 RLN02797.1 - 0.00037 19.8 1.7 0.0014 17.9 0.9 2.0 2 0 0 2 2 2 1 Nucleotide-sugar transporter ASFV_L11L PF05293.11 RLN02797.1 - 0.07 13.5 1.3 0.25 11.7 0.1 2.6 1 1 1 2 2 2 0 African swine fever virus (ASFV) L11L protein PUNUT PF16913.5 RLN02797.1 - 1.4 8.0 21.6 1.8 7.7 20.4 1.7 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Peroxidase_2 PF01328.17 RLN02798.1 - 1.8e-52 178.6 0.0 2.3e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Arm PF00514.23 RLN02820.1 - 3e-22 77.9 2.1 0.015 15.4 0.0 7.8 8 0 0 8 8 8 7 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN02820.1 - 3.4e-12 46.6 18.4 0.0016 18.9 0.9 5.8 4 1 2 6 6 6 5 HEAT-like repeat HEAT PF02985.22 RLN02820.1 - 2.3e-07 30.5 13.0 1.2 9.6 0.0 8.3 9 0 0 9 9 9 2 HEAT repeat DUF3145 PF11343.8 RLN02820.1 - 0.0067 16.0 0.1 4.7 6.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3145) HEAT_2 PF13646.6 RLN02820.1 - 0.0079 16.6 28.5 0.092 13.1 6.9 4.9 1 1 5 6 6 6 5 HEAT repeats tRNA_edit PF04073.15 RLN02820.1 - 0.014 15.5 5.1 0.14 12.2 0.1 3.5 2 1 2 4 4 4 0 Aminoacyl-tRNA editing domain Birna_VP3 PF01767.16 RLN02820.1 - 0.044 13.9 0.3 6.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Birnavirus VP3 protein DUF3361 PF11841.8 RLN02820.1 - 0.14 12.1 0.0 16 5.4 0.0 4.0 5 1 2 7 7 7 0 Domain of unknown function (DUF3361) Urocanase_C PF17392.2 RLN02820.1 - 1 8.7 4.9 4.4 6.7 0.1 3.7 3 1 0 4 4 4 0 Urocanase C-terminal domain Pkinase_Tyr PF07714.17 RLN02821.1 - 3.7e-29 101.8 0.0 5.7e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN02821.1 - 4.3e-26 91.8 0.0 7.4e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RLN02821.1 - 0.00071 19.0 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PA14 PF07691.12 RLN02822.1 - 0.054 13.3 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 PA14 domain Pkinase PF00069.25 RLN02824.1 - 8e-41 140.1 0.0 8.1e-37 127.0 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN02824.1 - 1.3e-23 83.6 0.0 3.3e-23 82.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN02824.1 - 2.1e-05 24.0 0.0 4.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN02824.1 - 0.00012 21.5 0.0 0.00025 20.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RLN02824.1 - 0.00048 19.0 1.7 0.0005 19.0 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 RLN02824.1 - 0.0052 15.8 0.0 0.0083 15.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RLN02824.1 - 0.049 13.6 1.3 0.054 13.4 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Cation_ATPase_C PF00689.21 RLN02826.1 - 7.2e-43 146.4 0.1 7.2e-43 146.4 0.1 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 RLN02826.1 - 6.5e-38 130.1 1.5 6.5e-38 130.1 1.5 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 RLN02826.1 - 2.6e-18 67.1 1.3 1.2e-14 55.1 1.3 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN02826.1 - 8.2e-17 61.1 0.0 1.5e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 RLN02826.1 - 1.6e-12 46.9 0.0 3.4e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RLN02826.1 - 6.4e-06 26.1 0.3 0.00098 18.9 0.5 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF3784 PF12650.7 RLN02826.1 - 0.78 10.0 12.2 1.1 9.5 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) MULE PF10551.9 RLN02859.1 - 6.7e-12 45.7 1.8 9.1e-12 45.2 0.5 2.0 2 0 0 2 2 2 1 MULE transposase domain Peptidase_C48 PF02902.19 RLN02859.1 - 8e-11 42.2 0.1 3.3e-10 40.2 0.1 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SWIM PF04434.17 RLN02859.1 - 0.0022 17.6 0.6 0.0046 16.6 0.6 1.5 1 0 0 1 1 1 1 SWIM zinc finger Ndc80_HEC PF03801.13 RLN02861.1 - 1.1e-21 77.0 0.0 1.6e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 HEC/Ndc80p family PseudoU_synth_2 PF00849.22 RLN02862.1 - 0.044 13.9 1.0 0.071 13.2 1.0 1.5 1 1 0 1 1 1 0 RNA pseudouridylate synthase Jnk-SapK_ap_N PF09744.9 RLN02862.1 - 4.9 7.4 28.3 10 6.4 1.7 2.5 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 GLYCAM-1 PF05242.11 RLN02863.1 - 0.099 12.8 0.1 0.1 12.7 0.1 1.0 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Sugar_tr PF00083.24 RLN02864.1 - 2.4e-16 59.6 6.6 2.9e-16 59.4 6.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN02864.1 - 5.9e-15 55.0 8.2 6.6e-15 54.9 8.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN02865.1 - 2.4e-16 59.6 6.6 2.9e-16 59.4 6.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN02865.1 - 5.9e-15 55.0 8.2 6.6e-15 54.9 8.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily ABC_tran PF00005.27 RLN02866.1 - 1.1e-05 25.9 0.3 2.3e-05 24.9 0.3 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 RLN02866.1 - 0.0014 18.3 0.1 0.0035 17.1 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN02866.1 - 0.0021 18.5 0.3 0.0038 17.6 0.3 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 RLN02866.1 - 0.0064 16.4 0.5 0.011 15.6 0.5 1.4 1 1 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 RLN02866.1 - 0.013 15.8 0.4 0.068 13.5 0.2 2.0 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.12 RLN02866.1 - 0.029 13.6 0.4 0.049 12.9 0.3 1.5 1 1 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 RLN02866.1 - 0.091 12.9 0.3 0.25 11.4 0.1 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_25 PF13481.6 RLN02866.1 - 0.11 12.0 0.3 0.22 11.1 0.2 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 RLN02866.1 - 0.17 11.4 1.1 4.5 6.8 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Tannase PF07519.11 RLN02867.1 - 2.6e-119 399.2 0.0 3.3e-119 398.8 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 RLN02867.1 - 0.00033 20.2 0.0 0.85 9.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 RLN02867.1 - 0.06 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase CTP_transf_like PF01467.26 RLN02897.1 - 1.9e-07 31.4 0.0 3.4e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 RLN02897.1 - 0.015 15.2 0.1 0.03 14.2 0.1 1.4 1 0 0 1 1 1 0 FAD synthetase MacB_PCD PF12704.7 RLN02897.1 - 0.017 15.5 0.0 0.028 14.8 0.0 1.3 1 0 0 1 1 1 0 MacB-like periplasmic core domain FYVE_2 PF02318.16 RLN02898.1 - 0.031 14.5 6.3 0.095 12.9 6.3 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger CEBP_ZZ PF16366.5 RLN02898.1 - 0.061 13.6 7.7 4.2 7.7 7.7 2.7 1 1 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Prok-RING_2 PF14445.6 RLN02898.1 - 0.12 12.6 3.2 0.33 11.2 3.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 DUF2162 PF09930.9 RLN02898.1 - 0.13 11.7 0.5 0.18 11.2 0.5 1.1 1 0 0 1 1 1 0 Predicted transporter (DUF2162) FYVE PF01363.21 RLN02898.1 - 0.49 10.6 11.2 1.2 9.3 11.2 1.7 1 0 0 1 1 1 0 FYVE zinc finger PET10 PF17316.2 RLN02899.1 - 0.17 11.4 0.1 0.24 10.9 0.1 1.1 1 0 0 1 1 1 0 Petite colonies protein 10 BLACT_WH PF17778.1 RLN02900.1 - 4.8e-08 32.9 0.4 1.1e-07 31.7 0.1 1.8 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain CM_2 PF01817.21 RLN02900.1 - 0.088 13.2 0.3 4.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Chorismate mutase type II FAD_binding_8 PF08022.12 RLN02904.1 - 1.8e-20 73.0 0.0 4.4e-20 71.8 0.0 1.6 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 RLN02904.1 - 1.2e-17 64.2 11.2 1.2e-17 64.2 9.2 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 RLN02904.1 - 2e-15 57.3 0.0 4.3e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 RLN02904.1 - 7e-05 23.4 0.0 0.32 11.7 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 RLN02904.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain TssN PF17555.2 RLN02904.1 - 5.8 6.2 8.5 8.8 5.6 8.5 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN FAD_binding_8 PF08022.12 RLN02905.1 - 4.1e-19 68.7 0.0 1.2e-18 67.1 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 RLN02905.1 - 1.1e-17 64.3 9.1 3.3e-17 62.8 9.1 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 RLN02905.1 - 1.1e-12 48.3 0.0 4.7e-12 46.3 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 RLN02905.1 - 3.6e-05 24.4 0.0 0.47 11.1 0.0 2.9 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain HPS3_C PF14763.6 RLN02905.1 - 0.04 13.3 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, C-terminal FAD_binding_6 PF00970.24 RLN02905.1 - 0.16 12.3 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain OrfB_Zn_ribbon PF07282.11 RLN02906.1 - 5.7e-16 58.2 2.3 1.2e-15 57.2 2.3 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HTH_OrfB_IS605 PF12323.8 RLN02906.1 - 2.2e-10 39.8 1.6 7.1e-10 38.2 1.6 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain OrfB_IS605 PF01385.19 RLN02906.1 - 0.00029 21.0 0.1 0.00029 21.0 0.1 2.2 2 0 0 2 2 2 1 Probable transposase Mu-like_Com PF10122.9 RLN02906.1 - 0.026 14.0 0.2 0.061 12.8 0.2 1.6 1 0 0 1 1 1 0 Mu-like prophage protein Com FAD_binding_8 PF08022.12 RLN02907.1 - 5.7e-19 68.2 0.0 1.2e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 RLN02907.1 - 1.1e-16 61.1 8.5 1.8e-16 60.4 7.8 1.8 1 1 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 RLN02907.1 - 5.9e-08 33.0 0.0 4.3e-07 30.2 0.0 2.3 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 RLN02907.1 - 0.00057 20.2 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 RLN02907.1 - 0.0016 19.1 0.0 0.83 10.3 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Cyt_bd_oxida_II PF02322.15 RLN02907.1 - 0.056 12.8 11.0 0.046 13.1 9.6 1.4 1 1 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II RTA1 PF04479.13 RLN02907.1 - 0.12 11.9 5.8 0.33 10.5 5.7 1.7 1 1 0 1 1 1 0 RTA1 like protein Tetraspanin PF00335.20 RLN02907.1 - 6.6 6.4 6.5 2 8.1 3.7 1.5 2 0 0 2 2 2 0 Tetraspanin family Metallophos PF00149.28 RLN02908.1 - 2.6e-14 54.2 0.5 4.9e-14 53.3 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RLN02908.1 - 0.00095 19.4 0.3 0.02 15.1 0.1 2.2 1 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain FAD_binding_8 PF08022.12 RLN02909.1 - 2.4e-61 204.6 0.0 3.6e-20 72.1 0.0 3.4 3 0 0 3 3 3 3 FAD-binding domain Ferric_reduct PF01794.19 RLN02909.1 - 3e-35 121.1 49.8 2.5e-18 66.4 11.2 3.8 3 0 0 3 3 3 3 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 RLN02909.1 - 1.2e-19 71.0 0.1 5.5e-07 29.8 0.0 5.7 4 2 0 4 4 4 3 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 RLN02909.1 - 9.9e-10 38.7 0.0 0.05 14.0 0.0 3.5 3 0 0 3 3 3 3 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 RLN02909.1 - 0.00023 21.8 0.0 23 5.7 0.0 4.5 4 0 0 4 4 4 2 Oxidoreductase NAD-binding domain DUF5110 PF17137.4 RLN02909.1 - 0.027 14.7 0.0 30 5.0 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5110) Defensin_propep PF00879.18 RLN02909.1 - 0.17 12.2 0.5 28 5.1 0.0 3.1 2 0 0 2 2 2 0 Defensin propeptide FAD_binding_8 PF08022.12 RLN02910.1 - 6.2e-42 142.1 0.0 1.7e-19 69.9 0.0 2.9 3 0 0 3 3 3 2 FAD-binding domain Ferric_reduct PF01794.19 RLN02910.1 - 5.5e-38 129.9 23.1 1.8e-19 70.1 2.1 2.7 2 0 0 2 2 2 2 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 RLN02910.1 - 1.6e-26 93.3 0.0 2.6e-13 50.4 0.0 3.9 3 1 0 3 3 3 3 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 RLN02910.1 - 2.6e-07 31.2 0.0 1.3 9.7 0.0 4.5 4 0 0 4 4 4 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 RLN02910.1 - 0.0012 19.1 0.0 2.9 8.3 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain FAD_binding_8 PF08022.12 RLN02911.1 - 4.9e-18 65.2 0.0 1.8e-17 63.4 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 RLN02911.1 - 1.1e-06 28.8 0.0 9.6e-06 25.8 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 RLN02911.1 - 1.2e-06 28.7 6.2 3e-06 27.3 6.2 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 RLN02911.1 - 0.0019 18.5 0.0 0.0041 17.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt_bd_oxida_I PF01654.17 RLN02911.1 - 0.0021 16.8 5.6 0.0021 16.8 5.6 1.8 2 1 0 3 3 3 1 Cytochrome bd terminal oxidase subunit I Ribosomal_S6 PF01250.17 RLN02915.1 - 2.8e-13 49.9 0.0 5.6e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6 DSS1_SEM1 PF05160.13 RLN02916.1 - 1.5e-16 60.2 16.2 1.9e-16 59.9 16.2 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family AAA PF00004.29 RLN02917.1 - 5.5e-53 178.9 0.0 1.3e-42 145.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN02917.1 - 2.2e-11 44.5 0.4 0.00019 21.9 0.0 3.8 2 1 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 RLN02917.1 - 3.9e-08 33.4 0.1 0.015 15.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RLN02917.1 - 1.3e-07 31.5 0.0 0.00018 21.3 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 RLN02917.1 - 1.9e-06 28.5 0.0 0.015 15.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 RLN02917.1 - 1e-05 25.6 0.0 0.09 12.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 RLN02917.1 - 1.6e-05 24.3 0.0 0.014 14.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain DUF815 PF05673.13 RLN02917.1 - 1.9e-05 23.9 0.0 0.24 10.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_22 PF13401.6 RLN02917.1 - 4.1e-05 23.9 0.2 0.024 14.9 0.0 3.2 2 2 2 4 4 3 1 AAA domain AAA_33 PF13671.6 RLN02917.1 - 5.1e-05 23.5 0.0 0.43 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 RLN02917.1 - 6.8e-05 22.9 0.0 0.28 11.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 RLN02917.1 - 0.00013 22.3 0.0 0.29 11.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 RLN02917.1 - 0.00022 20.9 6.0 0.0083 15.9 1.4 2.8 2 0 0 2 2 2 1 AAA+ lid domain Vps4_C PF09336.10 RLN02917.1 - 0.00024 21.1 0.0 0.0048 16.9 0.0 3.0 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_7 PF12775.7 RLN02917.1 - 0.00043 19.8 0.0 0.16 11.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 RLN02917.1 - 0.00067 20.0 0.0 0.073 13.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 RLN02917.1 - 0.00094 19.0 0.0 0.0048 16.6 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 RLN02917.1 - 0.0015 18.3 0.0 0.74 9.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 RLN02917.1 - 0.0023 17.8 0.0 0.76 9.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 RLN02917.1 - 0.003 17.5 0.1 1.1 9.1 0.1 2.3 2 0 0 2 2 2 1 NTPase Mg_chelatase PF01078.21 RLN02917.1 - 0.006 16.0 0.1 0.04 13.3 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 RLN02917.1 - 0.0074 16.2 0.1 1.1 9.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain ATPase PF06745.13 RLN02917.1 - 0.011 15.1 0.0 0.027 13.8 0.0 1.5 2 0 0 2 2 1 0 KaiC Parvo_NS1 PF01057.17 RLN02917.1 - 0.014 14.5 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 RLN02917.1 - 0.016 14.8 0.0 0.19 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 RLN02917.1 - 0.016 15.3 0.0 0.76 9.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain (Cdc48 subfamily) NB-ARC PF00931.22 RLN02917.1 - 0.019 14.2 0.0 2.5 7.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.6 RLN02917.1 - 0.024 15.1 0.1 1.7 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 RLN02917.1 - 0.024 13.9 0.0 7 5.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 RLN02917.1 - 0.058 13.1 0.0 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Inhibitor_I36 PF03995.13 RLN02917.1 - 0.059 13.3 5.9 2 8.4 0.1 3.7 4 0 0 4 4 4 0 Peptidase inhibitor family I36 ATPase_2 PF01637.18 RLN02917.1 - 0.11 12.4 0.0 9.8 6.0 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 RLN02917.1 - 0.13 12.0 0.0 22 4.9 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.15 RLN02917.1 - 0.14 12.0 0.0 23 4.9 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain Zeta_toxin PF06414.12 RLN02918.1 - 9.4e-14 51.1 0.0 1.5e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.6 RLN02918.1 - 1.2e-06 28.7 0.0 2.7e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain ACT PF01842.25 RLN02918.1 - 0.00027 20.6 0.0 0.0057 16.4 0.0 2.5 2 0 0 2 2 2 1 ACT domain Ploopntkinase3 PF18751.1 RLN02918.1 - 0.00089 19.2 0.0 0.18 11.7 0.0 2.4 2 0 0 2 2 2 2 P-loop Nucleotide Kinase3 AAA_18 PF13238.6 RLN02918.1 - 0.0011 19.5 0.1 0.014 15.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 RLN02918.1 - 0.0096 16.3 0.1 1.3 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN02918.1 - 0.012 16.0 0.4 0.11 12.9 0.0 2.6 2 1 0 3 3 3 0 AAA ATPase domain AAA_30 PF13604.6 RLN02918.1 - 0.15 11.7 0.0 0.42 10.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 RLN02918.1 - 0.2 11.4 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Cyclin_N PF00134.23 RLN02919.1 - 8.6e-09 35.2 0.0 2e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 RLN02919.1 - 0.00083 19.4 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Bromodomain PF00439.25 RLN02920.1 - 1.1e-86 285.0 0.1 1.7e-18 66.5 0.0 6.5 6 1 0 6 6 6 6 Bromodomain Slu7 PF11708.8 RLN02921.1 - 3.2e-88 296.0 18.9 2.2e-79 267.0 1.8 3.1 2 1 1 3 3 3 2 Pre-mRNA splicing Prp18-interacting factor ARF7EP_C PF14949.6 RLN02921.1 - 2.5 8.7 6.7 0.86 10.2 2.5 2.4 2 0 0 2 2 2 0 ARF7 effector protein C-terminus DUF4629 PF15442.6 RLN02921.1 - 5.2 7.3 12.2 0.66 10.2 7.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4629) PMM PF03332.13 RLN02922.1 - 9.3e-76 254.5 4.4 6.3e-74 248.5 4.4 2.0 1 1 0 1 1 1 1 Eukaryotic phosphomannomutase TMPIT PF07851.13 RLN02922.1 - 0.061 12.6 0.1 0.072 12.3 0.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein Sulfate_transp PF00916.20 RLN02923.1 - 2.8e-14 52.7 20.0 4.2e-14 52.1 20.0 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 RLN02923.1 - 1.4e-07 31.4 0.0 0.0023 18.0 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain STAS PF01740.21 RLN02923.1 - 2.3e-05 24.0 0.0 5.9e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 STAS domain Asp_protease_2 PF13650.6 RLN02924.1 - 0.11 13.1 0.1 0.43 11.3 0.1 2.1 1 0 0 1 1 1 0 Aspartyl protease RRM_1 PF00076.22 RLN02925.1 - 7.2e-12 44.9 0.0 2.1e-11 43.4 0.0 1.9 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ecm29 PF13001.7 RLN02926.1 - 9.3e-32 110.4 4.9 9.3e-32 110.4 4.9 2.9 3 1 0 3 3 3 1 Proteasome stabiliser DUF4231 PF14015.6 RLN02926.1 - 2.7 8.5 5.0 9.8 6.7 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Dak2 PF02734.17 RLN02926.1 - 5.7 6.8 9.3 1.4 8.8 2.1 3.0 2 0 0 2 2 2 0 DAK2 domain BTB PF00651.31 RLN02927.1 - 4.6e-05 23.6 0.0 8.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain P_C PF06640.11 RLN02927.1 - 0.04 14.0 1.5 0.093 12.9 1.5 1.6 1 0 0 1 1 1 0 P protein C-terminus Nuc_sug_transp PF04142.15 RLN02928.1 - 2.6e-22 79.4 12.2 3.9e-22 78.8 12.2 1.3 1 1 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 RLN02928.1 - 3.3e-07 29.8 4.6 3.3e-07 29.8 4.6 1.9 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 RLN02928.1 - 0.00032 20.9 15.1 0.00032 20.9 15.1 2.7 2 1 0 2 2 2 1 EamA-like transporter family HupE_UreJ_2 PF13795.6 RLN02929.1 - 0.0012 18.5 6.0 0.051 13.2 0.6 2.6 2 1 0 2 2 2 2 HupE / UreJ protein MerE PF05052.12 RLN02929.1 - 0.0086 16.0 2.5 0.037 13.9 2.5 2.1 1 0 0 1 1 1 1 MerE protein HupE_UreJ PF04955.12 RLN02929.1 - 0.018 14.5 0.4 0.018 14.5 0.4 2.7 2 1 1 3 3 3 0 HupE / UreJ protein YtpI PF14007.6 RLN02929.1 - 0.041 14.0 0.3 0.041 14.0 0.3 2.7 3 0 0 3 3 3 0 YtpI-like protein VIT1 PF01988.19 RLN02930.1 - 0.00028 20.8 0.0 0.00062 19.7 0.0 1.5 1 0 0 1 1 1 1 VIT family HupE_UreJ_2 PF13795.6 RLN02930.1 - 0.001 18.7 1.2 0.025 14.2 0.2 2.4 2 1 0 2 2 2 1 HupE / UreJ protein HupE_UreJ PF04955.12 RLN02930.1 - 0.029 13.8 0.3 0.029 13.8 0.3 3.1 3 1 0 3 3 3 0 HupE / UreJ protein MerE PF05052.12 RLN02930.1 - 0.64 10.0 7.6 0.047 13.6 2.1 2.0 2 0 0 2 2 2 0 MerE protein DUF4006 PF13179.6 RLN02930.1 - 6.4 6.8 5.7 1.4 8.9 0.5 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF4006) 4HBT PF03061.22 RLN02931.1 - 6e-05 23.3 0.1 0.0071 16.7 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily VIT1 PF01988.19 RLN02932.1 - 0.5 10.2 6.0 1.1 9.1 6.0 1.7 1 1 0 1 1 1 0 VIT family DUF202 PF02656.15 RLN02932.1 - 1.2 9.7 0.0 1.2 9.7 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Ank_2 PF12796.7 RLN02936.1 - 2.7e-15 56.7 1.3 0.0025 18.3 0.0 3.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN02936.1 - 6.3e-12 45.8 5.4 0.00091 19.8 0.1 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN02936.1 - 2.1e-07 31.1 4.1 0.26 11.7 0.1 5.6 2 1 5 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN02936.1 - 2.7e-05 24.2 1.1 25 5.9 0.0 6.0 6 0 0 6 6 6 1 Ankyrin repeat Surp PF01805.20 RLN02937.1 - 9.9e-15 54.3 1.5 1.7e-14 53.5 0.2 2.1 2 0 0 2 2 2 1 Surp module CTD_bind PF04818.13 RLN02937.1 - 1.3e-06 29.1 0.0 3.8e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CTK3 PF12243.8 RLN02937.1 - 0.0014 18.6 0.1 0.0031 17.5 0.1 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 RRM_1 PF00076.22 RLN02937.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GP17 PF17420.2 RLN02937.1 - 0.23 11.6 0.0 0.23 11.6 0.0 2.4 3 0 0 3 3 3 0 Superinfection exclusion gene product 17 Endomucin PF07010.12 RLN02938.1 - 0.00011 22.3 51.7 0.00011 22.3 51.7 2.1 2 0 0 2 2 2 1 Endomucin TMEM51 PF15345.6 RLN02938.1 - 0.0015 18.4 1.6 0.0015 18.4 1.6 2.5 1 1 1 2 2 2 1 Transmembrane protein 51 Baculo_E56 PF04639.12 RLN02938.1 - 0.04 13.2 0.9 0.04 13.2 0.9 1.5 2 0 0 2 2 2 0 Baculoviral E56 protein, specific to ODV envelope Orf78 PF06024.12 RLN02938.1 - 0.049 13.9 0.2 0.49 10.7 0.0 2.5 2 0 0 2 2 2 0 Orf78 (ac78) EphA2_TM PF14575.6 RLN02938.1 - 0.066 14.1 0.0 0.27 12.1 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CrgA PF06781.12 RLN02938.1 - 0.26 11.4 1.1 1.5 9.0 0.0 2.7 2 1 0 2 2 2 0 Cell division protein CrgA DUF3290 PF11694.8 RLN02938.1 - 0.32 10.9 0.7 0.88 9.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) EF-hand_1 PF00036.32 RLN02939.1 - 3e-75 242.3 40.2 2.2e-06 26.8 0.0 17.3 17 0 0 17 17 17 15 EF hand EF-hand_7 PF13499.6 RLN02939.1 - 1.8e-68 226.9 52.5 7.2e-10 39.2 0.4 10.2 9 1 1 10 10 10 10 EF-hand domain pair EF-hand_6 PF13405.6 RLN02939.1 - 2.9e-58 188.9 44.7 1.2e-05 24.8 0.2 16.6 16 1 1 17 17 17 14 EF-hand domain EF-hand_8 PF13833.6 RLN02939.1 - 1e-50 169.4 36.4 2.1e-05 24.3 0.6 13.9 10 4 4 14 14 14 14 EF-hand domain pair EF-hand_5 PF13202.6 RLN02939.1 - 5.3e-33 111.1 22.1 0.00034 20.0 0.1 12.6 12 0 0 12 12 12 7 EF hand EF-hand_11 PF08976.11 RLN02939.1 - 2.8e-14 53.8 9.3 0.0045 17.9 0.0 7.4 8 0 0 8 8 8 3 EF-hand domain EF-hand_9 PF14658.6 RLN02939.1 - 1.2e-09 38.4 13.0 0.2 12.0 0.0 9.9 10 2 0 10 10 10 2 EF-hand domain SPARC_Ca_bdg PF10591.9 RLN02939.1 - 5.3e-09 36.4 13.6 0.78 10.1 0.1 7.5 8 0 0 8 8 8 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RLN02939.1 - 1.9e-05 24.5 19.7 2.7 8.0 0.0 9.5 9 3 2 11 11 11 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 RLN02939.1 - 0.0031 17.8 4.6 1.9 8.9 0.0 5.7 6 0 0 6 6 6 1 EF-hand domain p25-alpha PF05517.12 RLN02939.1 - 0.0057 16.8 0.4 5.5 7.1 0.1 5.4 8 0 0 8 8 8 1 p25-alpha COR PF16095.5 RLN02939.1 - 0.0061 16.4 0.0 32 4.2 0.0 5.3 6 0 0 6 6 6 0 C-terminal of Roc, COR, domain LURAP PF14854.6 RLN02939.1 - 0.0087 16.0 0.0 0.027 14.4 0.0 1.8 1 0 0 1 1 1 1 Leucine rich adaptor protein Sec8_exocyst PF04048.14 RLN02939.1 - 0.1 12.5 1.5 8.1 6.3 0.0 3.5 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain EF-hand_10 PF14788.6 RLN02939.1 - 2 8.3 15.3 0.96 9.4 0.1 6.3 7 0 0 7 7 7 0 EF hand Ank_4 PF13637.6 RLN02940.1 - 2.9e-12 46.8 2.2 9.2e-06 26.1 0.1 4.8 2 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN02940.1 - 3.8e-09 37.0 0.1 0.0037 17.8 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN02940.1 - 3.1e-06 27.3 4.9 0.036 14.4 0.1 5.2 2 1 4 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN02940.1 - 0.0004 20.6 0.2 7.2 7.5 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat HAT PF02184.16 RLN02941.1 - 5.1e-23 80.7 65.5 2.1e-07 30.7 0.2 14.9 16 0 0 16 16 16 8 HAT (Half-A-TPR) repeat Suf PF05843.14 RLN02941.1 - 2e-16 60.8 25.6 2.1e-05 24.7 3.4 6.8 2 2 2 4 4 4 4 Suppressor of forked protein (Suf) TPR_14 PF13428.6 RLN02941.1 - 1.9e-13 50.0 39.0 0.0078 17.0 0.1 11.4 5 4 8 13 13 12 7 Tetratricopeptide repeat TPR_16 PF13432.6 RLN02941.1 - 1.3e-11 45.0 21.9 0.011 16.4 2.9 7.4 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 RLN02941.1 - 5e-11 43.0 3.8 0.15 12.6 1.6 6.2 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 RLN02941.1 - 1.5e-06 27.9 20.8 3.3 8.1 0.1 9.8 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN02941.1 - 7e-06 26.1 14.8 0.004 17.3 0.1 6.1 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN02941.1 - 8.8e-06 25.8 3.7 0.033 14.6 0.0 6.7 9 0 0 9 9 9 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 RLN02941.1 - 0.0015 18.6 26.4 0.056 13.4 1.0 7.6 6 3 2 8 8 8 1 Mad3/BUB1 homology region 1 U3_assoc_6 PF08640.11 RLN02941.1 - 0.17 12.0 0.2 0.17 12.0 0.2 6.6 4 3 4 8 8 8 0 U3 small nucleolar RNA-associated protein 6 TPR_8 PF13181.6 RLN02941.1 - 0.26 11.6 12.6 10 6.6 0.1 7.7 10 0 0 10 10 9 0 Tetratricopeptide repeat PilJ PF13675.6 RLN02941.1 - 3.4 7.7 9.8 8 6.5 0.1 3.9 4 0 0 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term TPR_12 PF13424.6 RLN02942.1 - 4.6e-08 33.2 0.5 0.0014 18.9 0.0 4.8 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN02942.1 - 0.00027 20.8 1.7 0.28 11.4 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN02942.1 - 0.0015 18.3 6.7 0.045 13.6 0.0 4.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN02942.1 - 0.0034 17.9 2.5 1.5 9.4 0.1 4.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN02942.1 - 0.0067 16.2 0.0 0.22 11.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN02942.1 - 0.017 15.3 0.0 0.21 11.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN02942.1 - 0.66 10.7 0.1 0.66 10.7 0.1 5.3 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN02942.1 - 8.2 7.5 16.1 19 6.4 0.1 5.9 6 2 1 7 7 7 0 Tetratricopeptide repeat DUF2183 PF09949.9 RLN02943.1 - 0.0053 17.1 0.2 0.035 14.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) DUF2207 PF09972.9 RLN02943.1 - 0.14 10.9 0.1 0.24 10.1 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2157 PF09925.9 RLN02943.1 - 0.19 11.5 2.7 0.36 10.6 2.7 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Phage_holin_3_6 PF07332.11 RLN02943.1 - 4.3 7.4 5.5 0.3 11.1 0.3 1.7 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III PH PF00169.29 RLN02944.1 - 1e-06 29.2 0.9 5.2e-06 26.9 0.9 2.0 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN02944.1 - 0.0051 17.1 0.1 0.011 16.0 0.1 1.5 1 1 0 1 1 1 1 Pleckstrin homology domain FAM220 PF15487.6 RLN02944.1 - 0.048 13.3 0.1 0.061 13.0 0.1 1.1 1 0 0 1 1 1 0 FAM220 family PH_11 PF15413.6 RLN02944.1 - 0.092 13.2 5.1 0.56 10.7 0.9 2.6 2 1 1 3 3 3 0 Pleckstrin homology domain PLAC8 PF04749.17 RLN02946.1 - 7.7e-17 62.1 13.0 2e-16 60.8 13.0 1.6 1 1 0 1 1 1 1 PLAC8 family DUF898 PF05987.13 RLN02946.1 - 0.061 12.4 0.0 0.087 11.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Elicitin PF00964.17 RLN02947.1 - 5.7e-28 96.9 2.7 1.6e-13 50.6 0.5 2.2 2 0 0 2 2 2 2 Elicitin MHYT PF03707.16 RLN02947.1 - 2 8.6 6.9 0.32 11.2 1.8 2.1 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Elicitin PF00964.17 RLN02948.1 - 1.8e-18 66.4 4.6 2.4e-18 66.0 4.6 1.2 1 0 0 1 1 1 1 Elicitin Penaeidin PF05927.11 RLN02948.1 - 0.034 14.9 2.3 3.6 8.4 0.1 2.3 2 0 0 2 2 2 0 Penaeidin Elicitin PF00964.17 RLN02949.1 - 5.6e-38 128.9 9.4 6.4e-20 71.1 1.1 2.2 2 0 0 2 2 2 2 Elicitin Fer2_4 PF13510.6 RLN02949.1 - 0.092 12.8 0.1 14 5.9 0.0 3.1 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain Elicitin PF00964.17 RLN02950.1 - 5.3e-14 52.1 0.1 7e-14 51.7 0.1 1.1 1 0 0 1 1 1 1 Elicitin Asp PF00026.23 RLN02951.1 - 3.5e-37 128.5 5.9 8.1e-37 127.3 5.9 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RLN02951.1 - 1.4e-06 28.6 1.2 5.2e-05 23.6 0.2 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 RLN02951.1 - 5.2e-05 23.1 0.0 8.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal DUF4381 PF14316.6 RLN02951.1 - 0.0043 17.3 1.6 0.0073 16.6 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) ASFV_J13L PF05568.11 RLN02951.1 - 0.017 14.8 0.0 0.043 13.6 0.0 1.7 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF2681 PF10883.8 RLN02951.1 - 0.047 14.1 0.8 0.088 13.2 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Elicitin PF00964.17 RLN02952.1 - 8.4e-18 64.3 0.3 1.1e-17 63.9 0.3 1.1 1 0 0 1 1 1 1 Elicitin Proteasome PF00227.26 RLN02953.1 - 2.5e-35 121.7 0.0 3.3e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Formyl_trans_C PF02911.18 RLN02955.1 - 0.0012 19.0 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain SPC22 PF04573.12 RLN02957.1 - 2.3e-49 167.2 0.2 1.5e-37 128.7 0.0 2.0 2 0 0 2 2 2 2 Signal peptidase subunit Tetraspanin PF00335.20 RLN02958.1 - 0.063 13.0 0.2 0.1 12.3 0.2 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF2975 PF11188.8 RLN02958.1 - 0.11 12.3 3.7 0.2 11.5 3.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) FG-GAP PF01839.23 RLN02959.1 - 0.00063 19.8 0.0 0.26 11.4 0.0 2.6 2 0 0 2 2 2 2 FG-GAP repeat BBS2_Mid PF14783.6 RLN02959.1 - 0.002 18.1 0.0 0.29 11.2 0.1 2.3 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.6 RLN02959.1 - 0.0031 18.1 2.1 0.6 10.7 0.0 2.5 2 0 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Itfg2 PF15907.5 RLN02959.1 - 0.057 12.4 0.0 0.26 10.3 0.0 1.8 2 0 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 Peptidase_M3 PF01432.20 RLN02960.1 - 2.3e-123 412.9 0.0 2.8e-123 412.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 RLN02960.1 - 0.078 12.6 0.2 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Sas10_Utp3 PF04000.15 RLN02961.1 - 0.0024 18.4 0.0 0.0099 16.5 0.0 2.1 1 1 0 1 1 1 1 Sas10/Utp3/C1D family HSF_DNA-bind PF00447.17 RLN02962.1 - 3.1e-30 104.7 1.5 4.4e-30 104.1 1.5 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Spc7 PF08317.11 RLN02962.1 - 0.12 11.2 0.1 0.17 10.8 0.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Snapin_Pallidin PF14712.6 RLN02962.1 - 0.16 12.4 0.3 0.16 12.4 0.3 1.6 2 0 0 2 2 2 0 Snapin/Pallidin OmpH PF03938.14 RLN02966.1 - 0.0027 18.1 7.0 0.061 13.6 1.2 2.3 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 RLN02966.1 - 0.15 11.4 8.8 0.22 10.9 8.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAS PF13851.6 RLN02966.1 - 0.21 10.9 8.3 0.21 10.9 1.9 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 RLN02966.1 - 0.87 10.3 3.5 3.1 8.5 0.2 2.4 2 0 0 2 2 2 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 RLN02966.1 - 0.92 9.5 13.0 9.1 6.3 13.0 2.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 THOC7 PF05615.13 RLN02966.1 - 1.5 9.1 13.6 4.5 7.6 0.9 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 HALZ PF02183.18 RLN02966.1 - 3 8.2 11.0 4.8 7.5 0.1 3.9 3 1 1 4 4 4 0 Homeobox associated leucine zipper Com_YlbF PF06133.11 RLN02966.1 - 7 7.3 10.6 17 6.1 0.7 2.4 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Jnk-SapK_ap_N PF09744.9 RLN02966.1 - 9.1 6.5 13.2 4.6 7.5 4.8 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 PH PF00169.29 RLN02974.1 - 1.1e-09 38.8 0.0 3.8e-08 33.8 0.0 2.2 1 1 0 1 1 1 1 PH domain zf-CCHC_2 PF13696.6 RLN02975.1 - 8.4e-28 95.8 27.9 5.2e-11 42.1 2.2 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC PF00098.23 RLN02975.1 - 4.2e-13 48.7 20.3 0.00018 21.4 4.0 3.4 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 RLN02975.1 - 2.3e-05 24.2 19.2 0.019 14.9 1.1 3.2 2 1 1 3 3 3 3 Zinc knuckle zf-CCHC_5 PF14787.6 RLN02975.1 - 0.00011 21.8 15.3 0.029 14.1 0.5 3.4 3 0 0 3 3 3 2 GAG-polyprotein viral zinc-finger HypA PF01155.19 RLN02975.1 - 3.1 7.8 6.4 3.5e+02 1.2 6.4 2.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CCHC_4 PF14392.6 RLN02975.1 - 3.2 7.5 12.1 7.8 6.3 0.5 3.2 3 0 0 3 3 3 0 Zinc knuckle zf_UBZ PF18439.1 RLN02975.1 - 3.3 7.4 11.6 11 5.7 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DZR PF12773.7 RLN02975.1 - 4.4 7.4 13.0 8e+02 0.2 13.0 2.5 1 1 0 1 1 1 0 Double zinc ribbon zf-HIT PF04438.16 RLN02975.1 - 4.6 7.2 16.8 3.9 7.4 0.8 3.2 2 1 1 3 3 3 0 HIT zinc finger eIF3g PF12353.8 RLN02975.1 - 9.7 6.6 18.4 0.38 11.2 0.6 3.0 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G Ank_5 PF13857.6 RLN02992.1 - 1.9e-19 69.4 2.2 2.8e-06 27.5 0.0 5.4 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN02992.1 - 3.7e-19 69.1 1.6 3e-05 24.5 0.0 4.9 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN02992.1 - 6.8e-16 58.4 0.0 0.0023 18.4 0.0 5.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN02992.1 - 2.3e-12 45.9 0.2 0.017 15.6 0.0 6.8 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 RLN02992.1 - 3.4e-07 30.4 0.1 0.037 14.5 0.0 4.8 4 1 0 4 4 4 2 Ankyrin repeat zf-B_box PF00643.24 RLN02992.1 - 0.0004 20.5 11.5 0.00076 19.6 11.5 1.4 1 0 0 1 1 1 1 B-box zinc finger TPR_12 PF13424.6 RLN02992.1 - 0.0076 16.5 0.0 0.034 14.4 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat RGS PF00615.19 RLN02992.1 - 0.015 15.6 0.4 0.25 11.6 0.2 3.0 2 1 0 2 2 2 0 Regulator of G protein signaling domain Siva PF05458.12 RLN02992.1 - 0.049 13.3 3.3 0.11 12.2 3.3 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Glyco_hydro_35 PF01301.19 RLN02993.1 - 1.6e-73 248.1 0.3 2.8e-73 247.3 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 GHD PF17834.1 RLN02993.1 - 1.9e-06 27.8 0.1 7.5e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Beta-sandwich domain in beta galactosidase BetaGal_dom4_5 PF13364.6 RLN02993.1 - 0.00046 20.7 0.0 1.2 9.8 0.0 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain DUF397 PF04149.12 RLN02993.1 - 0.085 12.9 0.2 12 6.1 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF397) Homeobox_KN PF05920.11 RLN02995.1 - 1.7e-16 59.8 0.5 3.7e-16 58.7 0.5 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 RLN02995.1 - 6.3e-11 42.0 2.7 8.2e-11 41.6 1.2 1.9 2 0 0 2 2 2 1 Homeodomain Homez PF11569.8 RLN02995.1 - 6.8e-05 22.3 0.2 0.0045 16.4 0.1 2.6 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez DUF5341 PF17276.2 RLN02995.1 - 0.0041 17.3 1.0 0.054 13.7 0.3 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5341) FaeA PF04703.12 RLN02995.1 - 0.12 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 FaeA-like protein HTH_Tnp_ISL3 PF13542.6 RLN02995.1 - 0.36 10.3 2.3 7.4 6.1 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 Syntaxin_2 PF14523.6 RLN02996.1 - 3e-16 59.6 6.9 4.1e-16 59.2 0.9 2.2 2 0 0 2 2 2 1 Syntaxin-like protein CorA PF01544.18 RLN02996.1 - 0.00088 18.7 1.1 0.0011 18.3 0.1 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Synaptobrevin PF00957.21 RLN02996.1 - 0.00095 18.9 1.1 0.00095 18.9 1.1 2.4 3 0 0 3 3 2 1 Synaptobrevin SNARE PF05739.19 RLN02996.1 - 0.0013 18.7 5.3 0.0013 18.7 5.3 2.1 2 1 0 2 2 1 1 SNARE domain AAA_13 PF13166.6 RLN02996.1 - 0.0018 17.0 3.2 0.0041 15.8 0.2 2.0 2 0 0 2 2 2 1 AAA domain Syntaxin PF00804.25 RLN02996.1 - 0.0043 16.8 5.9 0.67 9.6 0.2 2.5 2 1 0 2 2 2 2 Syntaxin Spectrin PF00435.21 RLN02996.1 - 0.035 14.6 4.4 1.4 9.4 0.3 3.1 3 0 0 3 3 3 0 Spectrin repeat DUF3802 PF12290.8 RLN02996.1 - 0.046 14.2 0.5 0.87 10.1 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) DUF3683 PF12447.8 RLN02996.1 - 0.21 11.7 1.0 1.5 8.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3683) HisKA_3 PF07730.13 RLN02996.1 - 0.26 11.8 4.4 18 5.9 0.1 3.3 3 1 0 3 3 3 0 Histidine kinase Yuri_gagarin PF15934.5 RLN02996.1 - 0.42 10.4 5.2 0.25 11.1 1.3 2.4 2 1 0 2 2 2 0 Yuri gagarin COG2 PF06148.11 RLN02996.1 - 0.45 10.6 2.8 3.1 7.9 0.3 2.5 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Nop25 PF09805.9 RLN02996.1 - 1.8 9.0 5.5 4.7 7.7 0.2 2.5 2 1 1 3 3 3 0 Nucleolar protein 12 (25kDa) DUF2203 PF09969.9 RLN02996.1 - 2 9.1 5.0 36 5.1 1.0 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) SKA2 PF16740.5 RLN02996.1 - 2.5 7.9 6.1 7.3 6.4 0.2 3.0 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Sec34 PF04136.15 RLN02996.1 - 2.9 7.8 6.8 4.8 7.1 0.1 3.1 3 1 0 3 3 3 0 Sec34-like family LRRFIP PF09738.9 RLN02996.1 - 3.4 7.1 9.1 0.5 9.8 1.1 2.3 1 1 1 2 2 2 0 LRRFIP family ApoLp-III PF07464.11 RLN02996.1 - 5.2 7.2 10.4 2.8 8.0 1.3 3.0 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF16 PF01519.16 RLN02996.1 - 5.3 7.6 7.1 6.9 7.2 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function DUF16 Laminin_II PF06009.12 RLN02996.1 - 5.4 7.0 9.6 7.7 6.5 0.6 3.4 2 1 1 3 3 3 0 Laminin Domain II Seryl_tRNA_N PF02403.22 RLN02996.1 - 8.7 6.6 8.8 2.6 8.3 0.6 3.1 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain AIRS_C PF02769.22 RLN02997.1 - 1e-22 81.0 0.1 1.5e-22 80.4 0.1 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 RLN02997.1 - 1.2e-09 38.7 0.1 2.9e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain PPS_PS PF02006.16 RLN02997.1 - 0.095 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Phosphopantothenate/pantothenate synthetase GcnA_N PF18229.1 RLN05646.1 - 0.057 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 N-acetyl-beta-D-glucosaminidase N-terminal domain SPRY PF00622.28 RLN05647.1 - 0.00049 20.2 0.0 0.00071 19.7 0.0 1.3 1 0 0 1 1 1 1 SPRY domain UPF0047 PF01894.17 RLN05648.1 - 6.8e-15 55.2 0.0 7.9e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Cnd2 PF05786.14 RLN05649.1 - 2.9e-69 234.6 75.4 3.2e-69 234.5 53.7 6.1 1 1 2 3 3 3 2 Condensin complex subunit 2 CNDH2_N PF06278.11 RLN05649.1 - 4.5e-05 23.6 0.3 4.5e-05 23.6 0.3 3.8 4 0 0 4 4 4 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Solute_trans_a PF03619.16 RLN05650.1 - 8.2e-93 310.7 12.5 9.7e-93 310.5 12.5 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Pex14_N PF04695.13 RLN05651.1 - 0.35 11.5 4.5 21 5.8 4.5 2.2 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PDT PF00800.18 RLN05652.1 - 2.6e-16 60.0 0.8 4.7e-16 59.1 0.8 1.4 1 0 0 1 1 1 1 Prephenate dehydratase SRP_SPB PF02978.19 RLN05652.1 - 0.0019 18.8 0.2 0.005 17.4 0.2 1.7 1 0 0 1 1 1 1 Signal peptide binding domain USP8_interact PF08941.10 RLN05653.1 - 0.0052 16.6 0.0 0.01 15.7 0.0 1.4 1 1 0 1 1 1 1 USP8 interacting Spc7 PF08317.11 RLN05653.1 - 0.14 11.0 3.2 0.49 9.2 0.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2497 PF10691.9 RLN05653.1 - 1.2 9.6 3.3 52 4.4 0.0 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2497) Cytochrom_B562 PF07361.11 RLN05654.1 - 0.004 17.8 5.8 0.004 17.8 5.8 3.9 4 2 0 4 4 4 1 Cytochrome b562 EspB_PE PF18625.1 RLN05654.1 - 0.0078 16.6 3.4 1.3 9.5 0.1 4.0 3 1 0 3 3 3 1 ESX-1 secreted protein B PE domain Nucleoporin_FG PF13634.6 RLN05654.1 - 0.0083 17.0 1.9 0.0083 17.0 1.9 2.6 2 1 0 2 2 2 1 Nucleoporin FG repeat region Exonuc_VII_L PF02601.15 RLN05654.1 - 0.96 9.0 13.9 1.1 8.7 3.0 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit FliJ PF02050.16 RLN05654.1 - 1.4 9.2 13.3 7 6.9 2.1 3.8 3 1 0 3 3 3 0 Flagellar FliJ protein SesA PF17107.5 RLN05654.1 - 1.5 9.0 7.7 1.3 9.2 0.3 3.3 3 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF883 PF05957.13 RLN05654.1 - 8.5 7.1 19.2 12 6.6 1.4 5.0 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF883) Ank_2 PF12796.7 RLN05655.1 - 1.7e-46 156.7 8.5 6e-14 52.4 0.5 5.8 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN05655.1 - 1.7e-28 95.5 13.6 0.067 13.8 0.1 11.8 11 0 0 11 11 11 8 Ankyrin repeat Ank_4 PF13637.6 RLN05655.1 - 1.8e-26 92.1 19.1 4.1e-07 30.4 0.1 8.4 4 3 5 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 RLN05655.1 - 5.2e-24 83.6 27.1 0.0076 16.7 0.1 11.5 12 1 1 13 13 13 8 Ankyrin repeat Ank_5 PF13857.6 RLN05655.1 - 2.1e-19 69.3 25.7 0.00027 21.1 0.1 10.3 3 2 7 11 11 11 9 Ankyrin repeats (many copies) F-box PF00646.33 RLN05655.1 - 0.0061 16.4 0.2 0.016 15.1 0.2 1.7 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.28 RLN05656.1 - 1.7e-17 62.4 0.2 4.1e-07 29.5 0.0 4.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 RLN05656.1 - 1.6e-16 60.6 11.1 1.4e-08 35.1 1.3 4.1 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 RLN05656.1 - 1.9e-16 58.7 8.4 3.2e-08 33.1 0.1 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 RLN05656.1 - 2.2e-15 55.8 0.3 0.051 14.0 0.0 5.2 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 RLN05656.1 - 9.9e-15 54.9 21.8 1.7e-07 31.8 4.3 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 RLN05656.1 - 5.1e-14 51.8 19.4 8.5e-06 26.2 2.6 5.4 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN05656.1 - 7.2e-14 50.7 5.7 4.4e-05 23.2 0.2 4.8 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 RLN05656.1 - 4.6e-12 46.0 14.5 1.7e-08 34.6 4.0 4.3 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN05656.1 - 2.4e-09 36.7 0.2 0.0003 20.8 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN05656.1 - 5.4e-09 35.6 0.3 0.099 12.3 0.0 4.8 4 1 2 6 6 6 3 TPR repeat TPR_10 PF13374.6 RLN05656.1 - 1e-08 34.7 11.6 0.0067 16.3 0.3 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 RLN05656.1 - 1.7e-08 34.4 13.7 5.6e-08 32.8 7.0 3.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 RLN05656.1 - 7.4e-08 31.9 6.7 0.00035 19.9 0.1 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat Wzy_C_2 PF11846.8 RLN05656.1 - 3.4e-06 27.1 6.5 0.047 13.6 0.4 3.4 1 1 2 3 3 3 3 Virulence factor membrane-bound polymerase, C-terminal TPR_4 PF07721.14 RLN05656.1 - 2.4e-05 24.5 32.4 0.054 14.1 0.2 5.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_20 PF14561.6 RLN05656.1 - 8.1e-05 22.9 10.9 0.36 11.2 0.7 4.4 2 1 3 5 5 5 3 Tetratricopeptide repeat BTAD PF03704.17 RLN05656.1 - 0.00017 22.1 6.6 0.00017 22.1 6.6 3.1 1 1 2 3 3 3 1 Bacterial transcriptional activator domain TPR_6 PF13174.6 RLN05656.1 - 0.00051 20.5 10.8 0.066 13.9 0.1 4.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 RLN05656.1 - 0.11 11.8 7.8 0.072 12.5 0.6 2.6 1 1 0 2 2 2 0 MalT-like TPR region ANAPC3 PF12895.7 RLN05656.1 - 0.16 12.2 0.7 1.2 9.4 0.0 2.5 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 CoaE PF01121.20 RLN05657.1 - 5.8e-56 189.0 0.1 7.7e-56 188.6 0.1 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 RLN05657.1 - 0.00053 20.5 0.1 0.0023 18.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RLN05657.1 - 0.027 14.6 0.0 0.1 12.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RLN05657.1 - 0.094 13.0 0.4 0.24 11.6 0.3 1.9 1 1 1 2 2 2 0 AAA domain Caa3_CtaG PF09678.10 RLN05657.1 - 2.6 7.5 5.3 4.1 6.8 5.3 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) LZ3wCH PF18517.1 RLN05658.1 - 2.7e-16 59.4 0.3 8.7e-16 57.8 0.0 2.0 2 0 0 2 2 2 1 Leucine zipper with capping helix domain Mnd1 PF03962.15 RLN05658.1 - 1.4e-09 38.1 0.0 0.00011 22.4 0.0 2.8 2 0 0 2 2 2 2 Mnd1 HTH domain Spc7 PF08317.11 RLN05658.1 - 0.058 12.3 0.4 0.082 11.8 0.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Ferric_reduct PF01794.19 RLN05659.1 - 1.6e-16 60.5 11.8 1.6e-16 60.5 11.8 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 RLN05659.1 - 1.1e-10 41.9 0.0 7.9e-10 39.1 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 RLN05659.1 - 5.8e-06 26.9 0.0 0.00021 21.9 0.0 2.8 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 RLN05659.1 - 2.4e-05 24.4 0.0 4.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.24 RLN05659.1 - 0.0075 16.6 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain DUF4079 PF13301.6 RLN05659.1 - 0.063 13.4 2.4 0.26 11.5 2.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) DUF5373 PF17343.2 RLN05659.1 - 4.2 7.2 9.2 11 5.8 9.2 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5373) DUF3712 PF12505.8 RLN05660.1 - 1.3e-11 44.8 0.1 6.9e-11 42.5 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3712) Synaptobrevin PF00957.21 RLN05660.1 - 0.044 13.6 2.5 0.12 12.2 2.5 1.7 1 0 0 1 1 1 0 Synaptobrevin DUF3139 PF11337.8 RLN05660.1 - 0.35 11.5 3.1 0.73 10.5 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) HSP90 PF00183.18 RLN05664.1 - 1.8e-133 446.2 10.6 2.1e-133 446.0 10.6 1.0 1 0 0 1 1 1 1 Hsp90 protein TRIQK PF15168.6 RLN05664.1 - 0.054 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family ATP11 PF06644.11 RLN05665.1 - 3.1e-24 86.2 0.1 4.2e-24 85.8 0.1 1.1 1 0 0 1 1 1 1 ATP11 protein DUF4996 PF16387.5 RLN05665.1 - 0.082 13.4 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function IBN_N PF03810.19 RLN05666.1 - 8.8e-08 32.0 0.0 2.6e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 RLN05666.1 - 1.7e-07 31.4 0.6 3.7e-06 27.1 0.6 3.1 2 1 0 2 2 2 1 Exportin 1-like protein RIX1 PF08167.12 RLN05666.1 - 3.4e-05 23.7 0.1 0.022 14.5 0.0 3.7 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis Cse1 PF08506.10 RLN05666.1 - 0.00021 20.2 0.1 0.0012 17.7 0.1 2.3 1 1 0 1 1 1 1 Cse1 HEAT PF02985.22 RLN05666.1 - 6.1 7.4 6.5 2.8e+02 2.2 0.0 5.8 6 0 0 6 6 6 0 HEAT repeat MCM_OB PF17207.3 RLN05667.1 - 1.1e-10 41.4 1.7 1.7e-10 40.8 1.7 1.3 1 0 0 1 1 1 1 MCM OB domain CTP_transf_3 PF02348.19 RLN05667.1 - 0.071 13.0 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Cytidylyltransferase ABATE PF07336.11 RLN05667.1 - 0.079 13.6 0.3 0.11 13.2 0.3 1.3 1 0 0 1 1 1 0 Putative stress-induced transcription regulator Cobl PF09469.10 RLN05667.1 - 0.081 13.2 1.3 0.15 12.3 1.3 1.4 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain E2F_TDP PF02319.20 RLN05668.1 - 6.3e-09 35.8 3.8 2.2e-07 30.8 0.5 3.6 3 1 1 4 4 4 1 E2F/DP family winged-helix DNA-binding domain CDC45 PF02724.14 RLN05668.1 - 1 7.6 8.0 1.5 7.0 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein CCDC53 PF10152.9 RLN05669.1 - 3.1e-37 128.4 23.2 5.6e-12 46.3 12.5 4.5 4 1 0 4 4 3 3 Subunit CCDC53 of WASH complex FYVE PF01363.21 RLN05669.1 - 2.8e-09 37.0 10.6 4.9e-09 36.2 10.6 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN05669.1 - 1.3e-05 25.4 3.6 1.3e-05 25.4 3.6 2.2 2 0 0 2 2 2 1 FYVE-type zinc finger Auxin_canalis PF05703.11 RLN05669.1 - 0.0056 16.6 7.9 0.0056 16.6 7.9 1.5 2 0 0 2 2 1 1 Auxin canalisation TolA_bind_tri PF16331.5 RLN05669.1 - 0.073 13.2 2.4 0.13 12.4 2.4 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation zf-piccolo PF05715.13 RLN05669.1 - 0.079 13.1 5.3 0.16 12.1 5.3 1.5 1 0 0 1 1 1 0 Piccolo Zn-finger MAT1 PF06391.13 RLN05669.1 - 0.24 11.2 7.4 0.38 10.6 7.4 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Ax_dynein_light PF10211.9 RLN05669.1 - 0.25 11.2 8.9 0.38 10.7 8.9 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain OmpH PF03938.14 RLN05669.1 - 0.28 11.5 9.1 0.47 10.8 9.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3138 PF11336.8 RLN05669.1 - 0.47 9.0 7.9 0.87 8.1 5.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) YliH PF10799.8 RLN05669.1 - 0.59 10.1 3.2 1.1 9.2 3.2 1.4 1 0 0 1 1 1 0 Biofilm formation protein (YliH/bssR) DivIC PF04977.15 RLN05669.1 - 4.2 7.2 7.5 9.4 6.1 7.5 1.6 1 0 0 1 1 1 0 Septum formation initiator HAUS-augmin3 PF14932.6 RLN05669.1 - 4.3 6.8 9.4 6.3 6.3 9.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 TMCO5 PF14992.6 RLN05669.1 - 5.1 6.6 7.3 7.7 6.0 7.3 1.2 1 0 0 1 1 1 0 TMCO5 family ISG65-75 PF11727.8 RLN05669.1 - 8.2 5.6 11.6 12 5.0 11.6 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein MCM PF00493.23 RLN05670.1 - 5.2e-86 287.4 0.2 1.2e-85 286.2 0.0 1.6 2 0 0 2 2 2 1 MCM P-loop domain MCM_lid PF17855.1 RLN05670.1 - 1.5e-25 89.4 1.4 1.5e-25 89.4 1.4 1.9 2 0 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 RLN05670.1 - 1.5e-09 37.6 0.1 4e-06 26.4 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RLN05670.1 - 3.1e-09 36.9 0.0 7.3e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 RLN05670.1 - 2.2e-05 24.3 0.0 5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RLN05670.1 - 3.3e-05 23.7 0.0 0.00044 20.0 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 RLN05670.1 - 0.0011 19.4 0.0 0.0033 17.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 RLN05670.1 - 0.0043 16.8 0.0 0.0099 15.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 RLN05670.1 - 0.021 15.2 1.2 0.071 13.5 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 RLN05670.1 - 0.027 13.8 0.5 0.073 12.4 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.6 RLN05670.1 - 0.044 14.1 0.3 2.2 8.6 0.0 2.6 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 RLN05670.1 - 0.051 13.8 0.1 0.63 10.3 0.0 2.9 2 1 0 2 2 2 0 AAA domain MCM_OB PF17207.3 RLN05670.1 - 0.056 13.3 0.1 0.096 12.5 0.1 1.4 1 0 0 1 1 1 0 MCM OB domain NTPase_1 PF03266.15 RLN05670.1 - 0.077 12.9 0.5 6.6 6.6 0.1 2.3 1 1 1 2 2 2 0 NTPase MMR_HSR1 PF01926.23 RLN05670.1 - 0.16 12.1 0.1 0.44 10.6 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 RLN05670.1 - 0.66 9.7 3.3 0.41 10.3 0.4 2.1 2 1 0 2 2 2 0 AAA domain GDPD PF03009.17 RLN05680.1 - 2.7e-47 161.7 0.0 4.1e-47 161.1 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Dockerin_1 PF00404.18 RLN05680.1 - 0.014 15.6 0.1 0.029 14.6 0.1 1.5 1 0 0 1 1 1 0 Dockerin type I domain EF-hand_5 PF13202.6 RLN05680.1 - 0.38 10.3 2.1 0.37 10.4 0.4 1.9 2 0 0 2 2 2 0 EF hand FGGY_N PF00370.21 RLN05681.1 - 1.7e-11 44.2 0.0 2e-08 34.1 0.0 2.1 1 1 1 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Biotin_lipoyl PF00364.22 RLN05682.1 - 1.7e-15 56.6 3.9 2.4e-15 56.1 3.9 1.2 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.19 RLN05682.1 - 0.00032 20.6 2.3 0.00064 19.6 2.3 1.4 1 1 0 1 1 1 1 Glycine cleavage H-protein S36_mt PF10937.8 RLN05682.1 - 0.0023 19.5 0.6 0.68 11.5 0.3 2.6 1 1 1 2 2 2 2 Ribosomal protein S36, mitochondrial HlyD_3 PF13437.6 RLN05682.1 - 0.21 12.3 2.9 1.1 10.0 0.1 2.4 1 1 1 2 2 2 0 HlyD family secretion protein Med20 PF08612.11 RLN05683.1 - 1.8e-13 50.4 0.0 4.2e-13 49.2 0.0 1.5 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex SDA1 PF05285.12 RLN05683.1 - 1.6 8.1 18.5 2.3 7.6 18.5 1.1 1 0 0 1 1 1 0 SDA1 IPK PF03770.16 RLN05684.1 - 1.8e-46 158.5 0.0 2.7e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase TPR_14 PF13428.6 RLN05685.1 - 7.9e-06 26.3 42.9 0.014 16.2 2.3 8.7 6 2 3 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 RLN05685.1 - 2.1e-05 24.9 34.6 0.041 14.4 0.1 7.2 4 2 3 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 RLN05685.1 - 0.00017 21.8 40.5 0.005 17.1 0.4 7.1 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN05685.1 - 0.00054 20.0 10.9 0.42 10.9 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN05685.1 - 0.0075 16.6 6.3 0.14 12.6 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 RLN05685.1 - 0.01 15.9 26.5 0.59 10.4 0.2 8.4 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN05685.1 - 0.017 15.0 13.4 7.4 6.6 0.1 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 RLN05685.1 - 0.057 13.1 11.5 0.89 9.3 0.0 6.0 6 0 0 6 6 6 0 TPR repeat TPR_6 PF13174.6 RLN05685.1 - 3.5 8.5 7.6 22 5.9 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN05685.1 - 4.2 7.7 12.8 0.37 11.1 1.0 4.1 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Transket_pyr PF02779.24 RLN05687.1 - 7.7e-61 204.9 0.0 1.3e-60 204.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 RLN05687.1 - 3.5e-48 164.1 0.0 5.3e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 RLN05687.1 - 1.7e-43 147.9 0.0 3.8e-43 146.8 0.0 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal WD40 PF00400.32 RLN05688.1 - 7e-05 23.5 2.8 0.38 11.7 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat PAP_central PF04928.17 RLN05689.1 - 3.2e-64 216.3 0.0 8.9e-64 214.8 0.0 1.8 1 0 0 1 1 1 1 Poly(A) polymerase central domain DHC_N2 PF08393.13 RLN05689.1 - 4.5e-57 194.0 0.1 4.5e-57 194.0 0.1 2.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 RLN05689.1 - 7.8e-27 94.1 0.0 9.3e-23 80.7 0.0 2.7 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 RLN05689.1 - 6.4e-25 87.7 0.0 2e-24 86.1 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region MT PF12777.7 RLN05689.1 - 3e-24 85.7 0.3 7.1e-24 84.5 0.3 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.7 RLN05689.1 - 1.2e-07 31.3 0.0 1.8e-06 27.5 0.0 2.5 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_16 PF13191.6 RLN05689.1 - 0.0012 19.3 1.5 0.11 12.9 0.1 4.4 3 0 0 3 3 2 1 AAA ATPase domain Dynein_C PF18199.1 RLN05689.1 - 0.0022 17.3 0.2 0.035 13.3 0.3 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_22 PF13401.6 RLN05689.1 - 0.012 15.9 0.0 0.078 13.3 0.0 2.5 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 RLN05689.1 - 0.015 14.4 0.0 0.038 13.1 0.0 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) PRY PF13765.6 RLN05689.1 - 0.023 14.3 0.0 0.093 12.4 0.0 2.1 1 0 0 1 1 1 0 SPRY-associated domain AAA_9 PF12781.7 RLN05689.1 - 0.03 13.5 0.0 0.074 12.2 0.0 1.6 1 0 0 1 1 1 0 ATP-binding dynein motor region Dynein_AAA_lid PF17852.1 RLN05689.1 - 0.04 14.0 0.2 0.23 11.5 0.0 2.6 2 0 0 2 2 1 0 Dynein heavy chain AAA lid domain AAA_33 PF13671.6 RLN05689.1 - 0.5 10.5 2.6 1.2 9.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain DP PF08781.10 RLN05689.1 - 0.84 9.5 6.4 2.2 8.2 6.4 1.7 1 0 0 1 1 1 0 Transcription factor DP DUF4148 PF13663.6 RLN05689.1 - 4.1 7.7 7.2 4.6 7.5 0.6 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) Arrestin_C PF02752.22 RLN05691.1 - 4.3e-17 62.8 0.0 2.3e-06 28.1 0.0 4.6 4 1 1 5 5 5 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 RLN05691.1 - 1.2e-12 48.1 0.0 4.8e-06 26.7 0.0 4.2 3 1 1 4 4 4 2 Arrestin (or S-antigen), N-terminal domain RPA_interact_M PF14767.6 RLN05691.1 - 0.0013 19.2 0.3 0.96 10.1 0.1 2.3 2 0 0 2 2 2 2 Replication protein A interacting middle Rgp1 PF08737.10 RLN05691.1 - 0.24 10.5 0.1 15 4.6 0.0 3.0 3 0 0 3 3 3 0 Rgp1 YukC PF10140.9 RLN05691.1 - 0.28 10.0 0.1 0.43 9.3 0.1 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC V_ATPase_I PF01496.19 RLN05692.1 - 0.71 7.7 7.3 1 7.2 7.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1515 PF07439.11 RLN05692.1 - 1.3 9.1 6.2 4.8 7.3 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF4407 PF14362.6 RLN05692.1 - 4.5 6.5 9.2 7.4 5.8 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 RLN05693.1 - 3.1e-77 259.5 0.0 4.1e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN05693.1 - 2.5e-36 125.3 0.0 3.2e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN05693.1 - 4.2e-05 23.0 0.2 6.6e-05 22.4 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 RLN05693.1 - 0.0077 15.9 0.2 0.013 15.2 0.2 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 RLN05693.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kinase-like PF14531.6 RLN05693.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 RLN05693.1 - 0.017 13.9 0.0 0.032 13.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 RLN05693.1 - 0.023 14.6 0.0 0.15 11.9 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Glyco_hydro_17 PF00332.18 RLN05694.1 - 0.00023 20.9 3.3 0.00028 20.6 1.8 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Cob_adeno_trans PF01923.18 RLN05695.1 - 1.5e-57 194.4 0.0 2e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 Cobalamin adenosyltransferase Nup153 PF08604.10 RLN05695.1 - 0.16 10.8 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup153-like Rhabdo_glycop PF00974.18 RLN05695.1 - 0.17 10.3 0.0 0.22 10.0 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein ABC2_membrane PF01061.24 RLN05697.1 - 4e-36 124.4 26.3 4e-36 124.4 26.3 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RLN05697.1 - 3.8e-27 95.5 0.0 5.5e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN05697.1 - 4.5e-09 36.5 0.0 0.0016 18.3 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN05697.1 - 0.00013 21.6 0.2 0.00042 20.0 0.2 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN05697.1 - 0.00016 21.7 0.1 0.00026 20.9 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 RLN05697.1 - 0.00052 20.4 0.0 0.00089 19.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 RLN05697.1 - 0.0013 19.3 0.0 0.0022 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 RLN05697.1 - 0.0015 18.0 0.0 1.8 7.9 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 RLN05697.1 - 0.013 15.4 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 RLN05697.1 - 0.026 14.8 0.1 0.06 13.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RLN05697.1 - 0.14 11.7 0.0 0.4 10.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 RLN05697.1 - 0.16 12.0 0.1 0.39 10.8 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.7 RLN05697.1 - 0.17 11.0 26.6 0.11 11.6 24.8 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein MULE PF10551.9 RLN05733.1 - 4.5e-12 46.2 0.1 1.2e-11 44.8 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 RLN05733.1 - 0.021 15.5 0.1 0.051 14.3 0.1 1.7 1 0 0 1 1 1 0 FAR1 DNA-binding domain cNMP_binding PF00027.29 RLN05734.1 - 7.4e-46 154.2 0.9 5.2e-11 42.5 0.1 4.5 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN05734.1 - 2.1e-17 63.2 46.1 4.8e-08 32.5 5.0 5.0 5 0 0 5 5 5 4 Ion transport protein Ion_trans_2 PF07885.16 RLN05734.1 - 2.1e-09 37.2 17.2 1.2e-07 31.5 4.6 4.6 4 0 0 4 4 4 3 Ion channel Arm PF00514.23 RLN05741.1 - 1.2e-48 161.8 25.5 0.0068 16.4 0.0 16.5 18 0 0 18 18 17 11 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN05741.1 - 2.6e-26 91.7 43.7 4.6e-07 30.2 0.4 12.6 9 3 4 14 14 14 11 HEAT-like repeat HEAT PF02985.22 RLN05741.1 - 5e-14 51.2 21.3 3.3 8.2 0.0 14.6 15 0 0 15 15 15 1 HEAT repeat DUF3361 PF11841.8 RLN05741.1 - 8e-06 25.9 0.0 1.5 8.8 0.0 8.1 9 3 2 11 11 11 1 Domain of unknown function (DUF3361) BAF250_C PF12031.8 RLN05741.1 - 0.00032 20.1 0.0 0.78 9.0 0.0 4.6 4 1 1 6 6 6 1 SWI/SNF-like complex subunit BAF250/Osa RHH_1 PF01402.21 RLN05741.1 - 0.0015 18.4 0.2 0.38 10.7 0.0 3.6 3 0 0 3 3 3 1 Ribbon-helix-helix protein, copG family HEAT_2 PF13646.6 RLN05741.1 - 0.002 18.5 55.8 0.069 13.6 2.5 9.3 3 1 8 12 12 11 3 HEAT repeats UME PF08064.13 RLN05741.1 - 0.0048 16.8 0.0 0.086 12.8 0.0 2.8 3 0 0 3 3 3 1 UME (NUC010) domain RYDR_ITPR PF01365.21 RLN05741.1 - 0.0064 15.9 0.0 13 5.1 0.0 4.0 3 1 0 3 3 3 0 RIH domain YopE PF03545.13 RLN05741.1 - 0.011 15.9 0.1 14 6.0 0.0 4.2 3 0 0 3 3 3 0 Yersinia virulence determinant (YopE) RPAP1_C PF08620.10 RLN05741.1 - 0.011 15.8 0.0 77 3.5 0.0 5.9 7 0 0 7 7 5 0 RPAP1-like, C-terminal NFACT-R_2 PF18297.1 RLN05741.1 - 0.016 15.4 2.8 2.3 8.5 0.0 4.4 5 2 2 7 7 6 0 NFACT protein RNA binding domain DUF4439 PF14530.6 RLN05741.1 - 0.018 15.7 26.2 2.4 8.8 0.2 7.3 5 3 4 9 9 9 0 Domain of unknown function (DUF4439) Tex_N PF09371.10 RLN05741.1 - 0.023 14.3 6.7 4.6 6.9 0.1 5.3 4 3 2 6 6 6 0 Tex-like protein N-terminal domain Pico_P2B PF01552.17 RLN05741.1 - 0.07 13.3 0.0 49 4.2 0.0 5.3 6 2 1 7 7 6 0 Picornavirus 2B protein GH97_C PF14509.6 RLN05741.1 - 0.14 12.4 2.9 17 5.7 0.1 4.8 4 1 2 6 6 5 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation Gp_dh_C PF02800.20 RLN05741.1 - 0.22 11.1 2.9 4.9 6.7 0.1 3.6 3 1 0 4 4 4 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DUF4055 PF13264.6 RLN05741.1 - 0.29 11.3 3.3 1.9 8.6 0.1 3.7 4 2 1 5 5 4 0 Domain of unknown function (DUF4055) DUF294_C PF10335.9 RLN05741.1 - 7.9 6.3 10.8 37 4.1 0.2 6.0 7 2 2 9 9 9 0 Putative nucleotidyltransferase substrate binding domain N_BRCA1_IG PF16158.5 RLN05746.1 - 8.6e-21 74.6 0.5 1.5e-20 73.8 0.1 1.6 2 0 0 2 2 2 1 Ig-like domain from next to BRCA1 gene UBA_4 PF14555.6 RLN05746.1 - 3.9e-11 42.6 4.7 2.9e-10 39.8 1.0 2.5 1 1 1 2 2 2 2 UBA-like domain TAP_C PF03943.13 RLN05746.1 - 0.11 12.2 0.3 0.11 12.2 0.3 1.8 2 0 0 2 2 2 0 TAP C-terminal domain HECT PF00632.25 RLN05747.1 - 1.1e-77 261.6 0.0 1.5e-77 261.2 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SUKH_5 PF14567.6 RLN05747.1 - 0.026 14.3 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall Amidinotransf PF02274.17 RLN05748.1 - 4.2e-09 35.9 0.0 4.9e-07 29.2 0.0 3.0 2 1 0 3 3 3 2 Amidinotransferase PAD_porph PF04371.15 RLN05748.1 - 0.047 13.0 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Porphyromonas-type peptidyl-arginine deiminase ABC2_membrane PF01061.24 RLN05759.1 - 9.3e-76 253.9 64.7 2.2e-42 144.9 28.4 2.2 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN05759.1 - 2.9e-34 118.5 0.0 1.2e-15 58.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN05759.1 - 7.1e-08 32.6 0.0 0.53 10.0 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN05759.1 - 3.3e-07 30.0 2.4 0.007 16.1 0.7 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN05759.1 - 3.5e-07 30.3 0.3 0.01 15.7 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 RLN05759.1 - 5.1e-07 30.2 0.3 0.057 13.8 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain SMC_N PF02463.19 RLN05759.1 - 3.5e-05 23.3 0.1 0.26 10.7 0.1 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RLN05759.1 - 7.8e-05 23.0 0.0 0.32 11.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.6 RLN05759.1 - 0.00047 20.7 0.8 0.11 12.9 0.1 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RLN05759.1 - 0.0023 17.2 0.3 0.43 9.8 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 RLN05759.1 - 0.0023 17.7 0.3 1.3 8.7 0.1 2.6 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 RLN05759.1 - 0.0051 17.2 0.2 5.9 7.3 0.1 3.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RLN05759.1 - 0.0057 17.2 0.0 3 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 RLN05759.1 - 0.0061 16.2 0.3 1.1 8.8 0.1 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 RLN05759.1 - 0.009 16.1 0.4 2.4 8.3 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase PDR_CDR PF06422.12 RLN05759.1 - 0.018 14.9 0.0 0.1 12.5 0.0 2.3 2 0 0 2 2 1 0 CDR ABC transporter AAA_24 PF13479.6 RLN05759.1 - 0.046 13.4 0.7 10 5.8 0.4 2.7 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 RLN05759.1 - 0.052 13.7 0.1 3.5 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RLN05759.1 - 0.11 12.4 4.1 3.9 7.4 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 RLN05759.1 - 0.12 12.4 0.4 6.9 6.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 RLN05759.1 - 0.15 12.0 0.5 2.5 8.0 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 RLN05759.1 - 0.15 12.3 0.1 26 5.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 RLN05759.1 - 0.24 11.0 3.3 3 7.4 0.6 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 RLN05759.1 - 0.3 10.8 0.9 6 6.6 0.4 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Mg_chelatase PF01078.21 RLN05759.1 - 0.43 9.9 3.0 14 5.0 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DUF87 PF01935.17 RLN05759.1 - 0.5 10.4 2.1 30 4.6 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain ABC2_membrane_3 PF12698.7 RLN05759.1 - 3.1 6.8 60.9 0.2 10.7 20.4 3.1 2 1 0 3 3 3 0 ABC-2 family transporter protein Aa_trans PF01490.18 RLN05760.1 - 2.2e-08 33.2 33.9 1.2e-07 30.8 33.9 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein SRTM1 PF15872.5 RLN05760.1 - 0.19 11.9 5.4 0.13 12.4 0.5 2.7 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 ABC_tran PF00005.27 RLN05761.1 - 8.6e-16 58.7 0.0 1.4e-15 58.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 RLN05761.1 - 8.3e-12 45.0 5.0 1.2e-11 44.5 5.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_29 PF13555.6 RLN05761.1 - 0.012 15.4 0.1 0.043 13.6 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN05761.1 - 0.018 15.4 1.5 0.041 14.3 0.4 2.0 2 1 1 3 3 3 0 AAA ATPase domain AAA_21 PF13304.6 RLN05761.1 - 0.023 14.5 0.0 0.73 9.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 RLN05761.1 - 0.024 14.9 0.1 0.086 13.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RLN05761.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 RLN05761.1 - 0.14 11.6 0.0 9.6 5.6 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 RLN05761.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ERG4_ERG24 PF01222.17 RLN05762.1 - 3.4e-72 243.5 3.7 4.1e-72 243.3 3.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 RLN05762.1 - 0.013 15.0 0.1 0.024 14.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) ABC2_membrane PF01061.24 RLN05763.1 - 9.2e-21 74.2 21.6 9.2e-21 74.2 21.6 1.6 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN05763.1 - 2.9e-09 36.7 0.7 7.7e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 RLN05763.1 - 3.9e-06 26.2 19.5 4.7e-06 25.9 19.5 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein RNase_PH PF01138.21 RLN05766.1 - 3.2e-16 60.1 0.1 2.5e-15 57.1 0.1 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RLN05766.1 - 1.2e-14 54.1 0.1 2e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Lipase_GDSL_2 PF13472.6 RLN05769.1 - 6e-18 65.9 0.0 8.2e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RLN05769.1 - 1.2e-15 58.0 0.0 1.5e-15 57.7 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 RLN05769.1 - 0.075 12.7 0.0 0.09 12.4 0.0 1.1 1 0 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX Lipase_GDSL_2 PF13472.6 RLN05770.1 - 4.9e-21 75.9 0.1 6.1e-21 75.6 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RLN05770.1 - 1.8e-14 54.2 0.0 2.7e-14 53.6 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 RLN05771.1 - 1.1e-44 152.9 0.2 8.9e-22 78.3 0.0 2.6 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RLN05771.1 - 1.7e-34 119.5 0.0 7.8e-17 61.9 0.0 2.5 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase zf-BED PF02892.15 RLN05773.1 - 2e-05 24.5 0.2 5.8e-05 23.0 0.2 1.8 1 0 0 1 1 1 1 BED zinc finger Dimer_Tnp_hAT PF05699.14 RLN05773.1 - 0.0079 16.0 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-C2H2_4 PF13894.6 RLN05773.1 - 2.9 9.0 5.0 3.1 8.9 1.9 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Ras PF00071.22 RLN05774.1 - 1.5e-09 37.7 0.0 1.7e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Zein-binding PF04576.15 RLN05775.1 - 0.0081 16.4 0.2 0.015 15.6 0.2 1.5 1 0 0 1 1 1 1 Zein-binding zf-C2H2_2 PF12756.7 RLN05775.1 - 0.12 12.8 0.1 0.27 11.6 0.1 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Ras PF00071.22 RLN05776.1 - 2.4e-51 173.5 0.4 2.9e-51 173.3 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN05776.1 - 2.6e-35 121.2 0.4 3.1e-35 121.0 0.4 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN05776.1 - 1.2e-15 57.4 0.3 1.3e-15 57.3 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RLN05776.1 - 1.2e-05 25.0 0.3 1.2e-05 25.0 0.3 1.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 RLN05776.1 - 2.9e-05 23.5 0.1 3.6e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RLN05776.1 - 5.4e-05 23.2 0.1 6.8e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 RLN05776.1 - 0.0044 16.5 0.1 0.0054 16.2 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 RLN05776.1 - 0.045 13.5 0.4 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN05776.1 - 0.067 13.5 0.1 0.14 12.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 RLN05776.1 - 0.067 12.3 0.0 0.21 10.6 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain RsgA_GTPase PF03193.16 RLN05776.1 - 0.068 13.1 0.3 0.63 9.9 0.1 2.1 1 1 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 RLN05776.1 - 0.09 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 RLN05776.1 - 0.092 12.5 0.1 0.48 10.2 0.0 1.8 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsZ_C PF12327.8 RLN05776.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.5 2 0 0 2 2 2 0 FtsZ family, C-terminal domain AAA_16 PF13191.6 RLN05776.1 - 0.13 12.6 0.0 0.16 12.3 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain DDE_Tnp_1_7 PF13843.6 RLN05777.1 - 5.7e-09 35.7 0.0 9.6e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Transposase IS4 ABC2_membrane PF01061.24 RLN05809.1 - 5.2e-30 104.4 26.1 5.2e-30 104.4 26.1 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 RLN05809.1 - 1.2 8.2 29.1 0.18 10.9 19.5 2.5 1 1 0 2 2 2 0 ABC-2 family transporter protein FixQ PF05545.11 RLN05809.1 - 2.2 8.3 7.3 7.8 6.5 2.8 2.9 1 1 1 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Ank_4 PF13637.6 RLN05810.1 - 9.4e-36 121.7 2.5 4.7e-12 46.2 0.1 7.8 5 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN05810.1 - 1.1e-35 122.1 3.6 4.1e-10 40.1 0.0 5.8 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 RLN05810.1 - 7.4e-32 108.4 17.8 1.4e-07 31.6 0.2 7.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 RLN05810.1 - 2.7e-29 98.0 8.0 1.2e-05 25.3 0.0 7.9 8 1 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 RLN05810.1 - 3.2e-21 75.1 9.0 4.6e-10 39.5 0.3 6.4 4 1 2 6 6 6 3 Ankyrin repeats (many copies) TIR_2 PF13676.6 RLN05810.1 - 6.4e-15 55.8 0.0 2.9e-14 53.7 0.0 2.2 2 0 0 2 2 2 1 TIR domain TIR PF01582.20 RLN05810.1 - 0.0023 17.8 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 TIR domain ABC_tran PF00005.27 RLN05811.1 - 0.0019 18.7 1.7 0.061 13.8 0.0 2.4 2 0 0 2 2 2 1 ABC transporter PAXIP1_C PF15364.6 RLN05811.1 - 5.3 7.4 6.3 4.2 7.7 3.2 2.1 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein ELO PF01151.18 RLN05812.1 - 2e-66 224.0 15.9 2.5e-66 223.8 15.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family LMF1 PF06762.14 RLN05813.1 - 9.9e-63 212.8 10.7 1.3e-62 212.4 10.7 1.1 1 0 0 1 1 1 1 Lipase maturation factor AAA_31 PF13614.6 RLN05824.1 - 1e-18 67.9 0.0 2e-18 66.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 RLN05824.1 - 1.7e-18 66.9 0.0 2.3e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 RLN05824.1 - 1.1e-13 51.2 0.1 6.8e-13 48.6 0.1 2.2 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 RLN05824.1 - 1.3e-10 41.0 0.0 2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 RLN05824.1 - 6.9e-10 38.8 0.3 7.2e-09 35.5 0.3 2.4 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 RLN05824.1 - 8.8e-07 28.4 0.0 1.3e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_26 PF13500.6 RLN05824.1 - 0.0018 18.2 2.2 0.94 9.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 RLN05824.1 - 0.0023 17.7 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 RLN05824.1 - 0.092 12.4 0.7 0.59 9.7 0.3 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 RLN05824.1 - 0.18 11.3 1.9 0.17 11.5 0.7 1.5 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 RLN05824.1 - 0.22 10.9 0.9 1.8 7.9 0.7 2.1 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Gcd10p PF04189.13 RLN05825.1 - 1.3e-58 198.4 0.0 2e-58 197.9 0.0 1.3 1 0 0 1 1 1 1 Gcd10p family Metallophos PF00149.28 RLN05826.1 - 4e-17 63.4 0.6 7.3e-17 62.5 0.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 RLN05826.1 - 4.2e-16 59.6 0.0 9.6e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 RLN05826.1 - 1.4e-14 54.4 0.0 3.2e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 RLN05826.1 - 0.0036 17.5 0.1 0.041 14.1 0.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Arteri_env PF01606.16 RLN05826.1 - 0.019 14.8 0.0 0.051 13.4 0.0 1.7 1 0 0 1 1 1 0 Arterivirus envelope protein EC042_2821 PF18740.1 RLN05828.1 - 0.11 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 EC042_2821-lke REase LpxB PF02684.15 RLN05829.1 - 1.8e-44 152.1 0.7 6e-26 91.2 0.0 2.9 3 1 0 3 3 3 2 Lipid-A-disaccharide synthetase Malic_M PF03949.15 RLN05845.1 - 4.6e-92 307.9 0.0 5.9e-92 307.6 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 RLN05845.1 - 2.5e-75 252.3 0.0 3.6e-75 251.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain malic PF00390.19 RLN05846.1 - 5.7e-42 143.6 0.0 8e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Tubulin PF00091.25 RLN05847.1 - 3.8e-57 193.7 0.0 7.2e-57 192.8 0.0 1.5 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RLN05847.1 - 2.8e-25 88.9 0.1 8.3e-24 84.2 0.1 2.3 1 1 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 RLN05847.1 - 0.016 15.5 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain DUF1940 PF09155.10 RLN05847.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) DnaJ_C PF01556.18 RLN05848.1 - 2.6e-35 121.7 0.0 4.1e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RLN05848.1 - 3.8e-27 94.2 1.1 6.6e-27 93.4 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 RLN05848.1 - 6.6e-13 48.8 19.6 1.1e-12 48.1 19.6 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 RLN05848.1 - 0.0065 16.4 11.5 0.074 13.0 0.8 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein MFS_1_like PF12832.7 RLN05848.1 - 0.06 12.2 6.3 0.1 11.5 4.7 2.0 2 0 0 2 2 2 0 MFS_1 like family TackOD1 PF18551.1 RLN05848.1 - 0.072 12.8 5.7 0.1 12.3 0.3 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zinc-ribbons_6 PF07191.12 RLN05848.1 - 0.36 10.8 5.1 0.7 9.9 5.1 1.4 1 0 0 1 1 1 0 zinc-ribbons Lar_restr_allev PF14354.6 RLN05848.1 - 0.37 11.2 12.9 3.7 8.0 0.1 4.0 3 2 1 4 4 4 0 Restriction alleviation protein Lar zf-RING_10 PF16685.5 RLN05848.1 - 1.9 8.7 6.5 1.2 9.3 0.2 2.4 1 1 1 2 2 2 0 zinc RING finger of MSL2 HypA PF01155.19 RLN05848.1 - 2.9 7.9 12.3 5.6 7.0 2.0 3.0 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2 PF00096.26 RLN05849.1 - 2.9e-19 68.4 23.4 3e-05 24.2 0.3 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN05849.1 - 4.6e-13 48.8 20.3 0.0079 17.0 0.2 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RLN05849.1 - 2.9e-11 43.2 27.5 1.3e-07 31.8 0.6 5.3 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_8 PF15909.5 RLN05849.1 - 2.7e-05 24.4 12.0 0.021 15.1 0.7 3.3 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 RLN05849.1 - 0.00099 19.3 5.1 10 6.6 0.3 4.3 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 RLN05849.1 - 0.003 17.7 5.6 11 6.1 0.1 3.8 1 1 3 4 4 4 1 Aberrant zinc-finger zf-C2H2_6 PF13912.6 RLN05849.1 - 0.0086 16.1 12.8 7.9 6.6 0.5 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RLN05849.1 - 0.064 13.0 11.6 0.83 9.5 0.1 4.6 4 0 0 4 4 4 0 C2H2-type zinc-finger domain FOXP-CC PF16159.5 RLN05849.1 - 0.068 13.8 6.6 1.2 9.8 0.1 3.4 3 1 1 4 4 4 0 FOXP coiled-coil domain zf-met PF12874.7 RLN05849.1 - 0.11 13.0 3.7 4.1 7.9 0.1 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Ogr_Delta PF04606.12 RLN05849.1 - 0.15 12.1 5.0 1.5 8.8 0.1 3.3 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger TetR_C_20 PF17925.1 RLN05849.1 - 0.17 12.2 0.1 0.28 11.5 0.1 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain zf_Hakai PF18408.1 RLN05849.1 - 0.17 11.6 0.0 0.17 11.6 0.0 3.6 4 0 0 4 4 4 0 C2H2 Hakai zinc finger domain CHORD PF04968.12 RLN05849.1 - 0.38 11.5 9.1 14 6.5 0.2 3.5 2 1 1 3 3 3 0 CHORD Sina PF03145.16 RLN05849.1 - 1.8 8.5 11.0 0.12 12.3 2.4 2.2 1 1 1 2 2 2 0 Seven in absentia protein family zf-C2H2_11 PF16622.5 RLN05849.1 - 2.6 7.9 13.2 4.1 7.2 0.6 4.2 4 0 0 4 4 4 0 zinc-finger C2H2-type CBF PF03914.17 RLN05858.1 - 6.3e-32 110.9 0.5 1.9e-31 109.4 0.5 1.8 1 0 0 1 1 1 1 CBF/Mak21 family DUF1455 PF07306.11 RLN05858.1 - 0.099 12.6 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) Rotamase PF00639.21 RLN05859.1 - 3.5e-15 56.7 0.1 5.4e-11 43.3 0.0 2.9 2 1 0 2 2 2 2 PPIC-type PPIASE domain Rotamase_3 PF13616.6 RLN05859.1 - 3.4e-13 50.2 0.1 1.8e-10 41.4 0.0 3.1 2 1 1 3 3 3 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 RLN05859.1 - 0.00034 21.4 0.0 0.00086 20.1 0.0 2.0 1 1 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 RLN05859.1 - 0.00083 19.4 0.1 0.0023 18.0 0.0 1.8 2 0 0 2 2 2 1 WW domain DUF1690 PF07956.11 RLN05859.1 - 0.064 13.7 0.1 0.1 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Glyco_hyd_101C PF17451.2 RLN05859.1 - 0.15 12.3 0.1 0.28 11.5 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain ThiD2 PF17792.1 RLN05859.1 - 0.34 11.4 2.4 1.1 9.7 0.1 2.1 1 1 1 2 2 2 0 ThiD2 family Peptidase_M14 PF00246.24 RLN05860.1 - 2e-17 63.9 0.5 5.7e-17 62.5 0.5 1.7 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 RLN05860.1 - 0.0056 15.8 0.2 0.54 9.3 0.0 2.3 2 0 0 2 2 2 2 Succinylglutamate desuccinylase / Aspartoacylase family BUD22 PF09073.10 RLN05860.1 - 0.31 10.3 20.2 0.57 9.5 20.2 1.3 1 0 0 1 1 1 0 BUD22 ROS_MUCR PF05443.11 RLN05861.1 - 0.091 12.8 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein AA_permease_2 PF13520.6 RLN05862.1 - 9.3e-42 143.3 26.9 9.3e-42 143.3 26.9 2.0 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 RLN05862.1 - 1.1e-28 100.1 29.1 1.1e-28 100.1 29.1 2.2 1 1 1 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 RLN05862.1 - 1.1e-12 47.8 3.6 1.1e-12 47.8 3.6 3.1 3 0 0 3 3 3 1 C-terminus of AA_permease Arteri_Gl PF00951.18 RLN05862.1 - 4.1 7.2 9.3 3 7.6 6.0 2.4 1 1 1 2 2 2 0 Arterivirus GL envelope glycoprotein ABC_membrane PF00664.23 RLN05863.1 - 8.2e-19 68.3 9.5 8e-15 55.2 2.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN05863.1 - 5.2e-16 59.4 0.0 1.1e-15 58.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Nexin_C PF08628.12 RLN05863.1 - 0.00093 19.7 0.1 0.0021 18.6 0.1 1.5 1 0 0 1 1 1 1 Sorting nexin C terminal AAA_29 PF13555.6 RLN05863.1 - 0.012 15.3 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 RLN05863.1 - 0.034 13.9 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RLN05863.1 - 0.061 13.7 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 RLN05863.1 - 0.078 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase ABC_membrane_3 PF13748.6 RLN05863.1 - 0.13 11.5 5.9 0.36 10.0 0.3 2.4 2 0 0 2 2 2 0 ABC transporter transmembrane region NACHT PF05729.12 RLN05863.1 - 0.17 11.8 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 NACHT domain GCK PF07802.11 RLN05864.1 - 0.0036 17.7 0.7 0.0078 16.6 0.7 1.5 1 0 0 1 1 1 1 GCK domain CX9C PF16860.5 RLN05864.1 - 0.0095 15.9 0.9 0.023 14.7 0.9 1.6 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Adap_comp_sub PF00928.21 RLN05865.1 - 1.4e-20 73.8 0.0 2.3e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 RLN05865.1 - 0.0064 16.0 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain PapD-like PF14874.6 RLN05866.1 - 6.4e-07 29.5 0.1 1.2e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 Flagellar-associated PapD-like DUF5427 PF10310.9 RLN05866.1 - 0.17 10.8 1.7 0.42 9.5 1.7 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5427) Malate_synthase PF01274.22 RLN05885.1 - 0.079 11.2 0.7 0.086 11.1 0.6 1.2 1 1 0 1 1 1 0 Malate synthase DUF1908 PF08926.11 RLN05885.1 - 0.092 11.8 0.0 0.3 10.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1908) DUF1727 PF08353.10 RLN05885.1 - 0.14 12.1 0.9 0.95 9.4 0.1 2.4 2 1 0 3 3 3 0 Domain of unknown function (DUF1727) Ribosomal_L27A PF00828.19 RLN05886.1 - 2e-11 44.7 0.3 2.5e-11 44.3 0.1 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF5026 PF16429.5 RLN05886.1 - 0.19 11.9 0.4 0.26 11.4 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5026) Pkinase PF00069.25 RLN05887.1 - 1.5e-17 63.8 0.0 3.5e-16 59.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN05887.1 - 9e-14 51.4 0.0 5.4e-13 48.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_2 PF07719.17 RLN05889.1 - 1.8e-11 43.2 15.4 3.8e-05 23.5 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN05889.1 - 2.5e-10 39.7 10.8 0.00046 19.9 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN05889.1 - 7.3e-08 32.9 11.9 0.00056 20.5 0.0 4.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN05889.1 - 5.3e-07 29.2 1.5 0.01 15.8 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN05889.1 - 1.2e-06 28.1 6.8 4.9e-06 26.1 0.0 4.3 4 1 1 5 5 5 2 TPR repeat TPR_17 PF13431.6 RLN05889.1 - 2.3e-06 27.6 0.1 1.8e-05 24.8 0.0 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN05889.1 - 2.8e-06 27.1 12.1 0.047 13.9 0.0 5.5 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN05889.1 - 4.9e-06 26.2 6.7 0.017 15.0 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN05889.1 - 1.9e-05 25.1 4.7 0.34 11.8 0.1 4.5 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN05889.1 - 0.00093 19.7 0.1 0.00093 19.7 0.1 3.3 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN05889.1 - 0.0011 19.2 13.5 0.013 15.8 0.6 4.7 2 1 1 4 4 4 1 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 RLN05889.1 - 0.0015 18.1 0.2 0.016 14.7 0.0 2.1 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain TPR_4 PF07721.14 RLN05889.1 - 0.0058 17.1 1.1 1.4 9.7 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Complex1_LYR PF05347.15 RLN05889.1 - 0.012 15.7 1.3 0.23 11.5 0.1 3.1 3 0 0 3 3 3 0 Complex 1 protein (LYR family) TPR_6 PF13174.6 RLN05889.1 - 0.014 16.0 0.6 1.9 9.3 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 RLN05889.1 - 0.084 13.3 6.3 0.11 13.0 3.4 2.5 1 1 2 3 3 3 0 Bacterial transcriptional activator domain DUF4192 PF13830.6 RLN05889.1 - 0.12 12.5 2.2 0.064 13.3 0.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) HBM PF16591.5 RLN05889.1 - 0.31 10.4 8.1 5.4 6.4 0.0 2.6 2 1 0 2 2 2 0 Helical bimodular sensor domain AAA PF00004.29 RLN05890.1 - 1e-59 200.7 0.1 1.1e-28 100.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Methyltransf_10 PF05971.12 RLN05890.1 - 4.5e-51 174.0 0.6 1.6e-49 168.8 0.6 2.7 1 1 0 1 1 1 1 RNA methyltransferase AAA_16 PF13191.6 RLN05890.1 - 3.3e-10 40.6 3.8 1.2e-05 25.8 0.0 3.5 3 1 0 3 3 2 2 AAA ATPase domain AAA_lid_3 PF17862.1 RLN05890.1 - 2.2e-09 37.0 1.2 0.0012 18.6 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain MTS PF05175.14 RLN05890.1 - 5.4e-09 35.8 0.0 1.4e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain IstB_IS21 PF01695.17 RLN05890.1 - 7.9e-09 35.5 0.1 0.00011 22.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.13 RLN05890.1 - 1.8e-08 34.0 0.3 0.0052 16.0 0.0 2.5 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_33 PF13671.6 RLN05890.1 - 2e-08 34.5 0.0 0.0034 17.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 RLN05890.1 - 7.9e-08 32.9 0.0 0.017 15.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 RLN05890.1 - 9.4e-07 28.7 0.7 0.047 13.4 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RLN05890.1 - 1.4e-06 28.3 0.2 0.0085 16.1 0.0 3.2 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) NACHT PF05729.12 RLN05890.1 - 2.7e-06 27.4 3.8 0.026 14.4 0.0 3.8 3 2 1 4 4 3 2 NACHT domain Sigma54_activat PF00158.26 RLN05890.1 - 3e-06 27.0 0.0 0.0031 17.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_2 PF07724.14 RLN05890.1 - 3.7e-06 27.2 0.0 0.0034 17.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 RLN05890.1 - 9.3e-06 25.7 0.0 0.031 14.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RLN05890.1 - 9.3e-06 26.0 0.4 0.19 12.0 0.0 4.3 4 1 0 4 4 3 1 AAA domain AAA_17 PF13207.6 RLN05890.1 - 3.4e-05 24.3 0.0 0.45 10.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 RLN05890.1 - 4.7e-05 22.9 0.0 0.051 13.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TsaE PF02367.17 RLN05890.1 - 6.4e-05 22.9 0.0 0.36 10.8 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 RLN05890.1 - 0.00011 22.2 2.5 0.015 15.2 0.0 3.2 4 0 0 4 4 2 1 NTPase ABC_tran PF00005.27 RLN05890.1 - 0.00014 22.4 0.0 1.6 9.2 0.0 3.6 2 2 0 2 2 2 2 ABC transporter Zeta_toxin PF06414.12 RLN05890.1 - 0.0002 20.7 0.1 0.0062 15.8 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.6 RLN05890.1 - 0.00022 21.6 0.1 0.044 14.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 RLN05890.1 - 0.00022 21.6 0.0 0.82 10.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.6 RLN05890.1 - 0.00044 20.0 0.3 0.075 12.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 RLN05890.1 - 0.00048 20.0 0.1 0.7 9.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 RLN05890.1 - 0.00055 19.9 0.0 1.6 8.5 0.0 2.7 3 0 0 3 3 2 2 Bacterial dnaA protein UPF0020 PF01170.18 RLN05890.1 - 0.0009 19.0 0.1 0.0048 16.6 0.0 2.1 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 DUF815 PF05673.13 RLN05890.1 - 0.0015 17.8 0.0 1.2 8.2 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF815) PrmA PF06325.13 RLN05890.1 - 0.0018 17.7 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NB-ARC PF00931.22 RLN05890.1 - 0.0021 17.3 0.0 0.39 9.9 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 RLN05890.1 - 0.0037 17.0 0.1 1.5 8.5 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_11 PF13086.6 RLN05890.1 - 0.0038 17.1 0.0 0.046 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 RLN05890.1 - 0.0052 15.9 0.0 0.16 11.1 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 RLN05890.1 - 0.0098 15.4 0.0 4 6.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 RLN05890.1 - 0.015 15.6 0.0 0.84 9.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 RLN05890.1 - 0.017 14.8 0.2 0.22 11.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain cobW PF02492.19 RLN05890.1 - 0.022 14.3 0.5 2.6 7.6 0.0 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 RLN05890.1 - 0.027 14.2 0.3 2.6 7.7 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase KTI12 PF08433.10 RLN05890.1 - 0.04 13.4 0.1 0.91 8.9 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DUF2075 PF09848.9 RLN05890.1 - 0.042 13.1 0.5 9.6 5.3 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 RLN05890.1 - 0.05 13.7 0.0 3.8 7.6 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain APS_kinase PF01583.20 RLN05890.1 - 0.059 13.3 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_25 PF13481.6 RLN05890.1 - 0.071 12.7 0.3 2.6 7.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 RLN05890.1 - 0.078 12.4 0.0 2.6 7.4 0.0 2.8 2 1 1 3 3 3 0 RecF/RecN/SMC N terminal domain GvpD PF07088.11 RLN05890.1 - 0.096 11.3 0.0 0.66 8.5 0.0 2.1 2 0 0 2 2 2 0 GvpD gas vesicle protein T2SSE PF00437.20 RLN05890.1 - 0.1 11.6 0.1 0.38 9.8 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein Methyltransf_25 PF13649.6 RLN05890.1 - 0.11 13.2 0.0 0.56 11.0 0.0 2.3 1 0 0 1 1 1 0 Methyltransferase domain RHH_6 PF16762.5 RLN05890.1 - 0.12 13.0 0.3 4.5 8.0 0.1 2.7 2 0 0 2 2 2 0 Ribbon-helix-helix domain Helicase_C_2 PF13307.6 RLN05892.1 - 2.5e-13 50.6 0.0 9.7e-13 48.6 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 RLN05892.1 - 1.5e-11 44.2 0.1 3e-11 43.3 0.1 1.6 1 0 0 1 1 1 1 DEAD_2 YadA_stalk PF05662.14 RLN05892.1 - 0.18 12.2 0.7 21 5.6 0.1 2.9 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin UFC1 PF08694.11 RLN05893.1 - 7.3e-48 162.1 0.3 1.8e-46 157.6 0.3 2.0 1 1 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 IQ PF00612.27 RLN05914.1 - 9.2e-11 40.6 14.5 0.015 15.1 0.3 5.3 4 0 0 4 4 4 4 IQ calmodulin-binding motif V_ATPase_I PF01496.19 RLN05914.1 - 0.61 7.9 6.2 0.96 7.3 6.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PH PF00169.29 RLN05915.1 - 0.014 15.9 0.0 0.04 14.4 0.0 1.9 1 0 0 1 1 1 0 PH domain Homeodomain PF00046.29 RLN05922.1 - 3e-29 100.6 10.9 8.9e-09 35.1 0.1 4.6 3 1 0 3 3 3 3 Homeodomain PHD PF00628.29 RLN05922.1 - 2.5e-06 27.2 10.7 4.6e-06 26.4 10.7 1.4 1 0 0 1 1 1 1 PHD-finger Homeobox_KN PF05920.11 RLN05922.1 - 0.00035 20.4 1.0 0.63 10.0 0.1 3.7 3 0 0 3 3 3 2 Homeobox KN domain C1_2 PF03107.16 RLN05922.1 - 0.0037 17.5 1.3 0.0072 16.6 1.3 1.4 1 0 0 1 1 1 1 C1 domain Prok-RING_1 PF14446.6 RLN05922.1 - 0.025 14.5 4.0 0.058 13.3 4.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 RLN05922.1 - 0.03 14.2 7.8 0.062 13.2 7.8 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Homez PF11569.8 RLN05922.1 - 0.032 13.7 0.9 20 4.7 0.0 3.9 4 0 0 4 4 4 0 Homeodomain leucine-zipper encoding, Homez Cytochrom_CIII PF02085.16 RLN05922.1 - 0.36 11.2 5.5 0.93 9.9 5.5 1.7 1 0 0 1 1 1 0 Class III cytochrome C family Zn_ribbon_17 PF17120.5 RLN05922.1 - 0.5 10.0 7.6 0.99 9.1 7.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 RLN05922.1 - 2 8.8 10.8 3.2 8.2 10.8 1.3 1 0 0 1 1 1 0 Ring finger domain PHD_2 PF13831.6 RLN05922.1 - 3 7.5 5.9 5.9 6.5 5.9 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_9 PF13901.6 RLN05922.1 - 3.2 7.7 9.1 6.7 6.6 9.1 1.5 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-RING_5 PF14634.6 RLN05922.1 - 5.2 7.1 11.2 8.3 6.5 11.2 1.3 1 0 0 1 1 1 0 zinc-RING finger domain 5_3_exonuc_N PF02739.16 RLN05923.1 - 3.1e-27 95.4 0.2 4.6e-27 94.9 0.2 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 RLN05923.1 - 1.8e-13 50.9 0.0 3.1e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HrpF PF06266.12 RLN05923.1 - 0.067 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 HrpF protein MULE PF10551.9 RLN05946.1 - 2.7e-17 63.0 0.5 6.3e-16 58.6 0.1 2.6 3 0 0 3 3 3 1 MULE transposase domain DUF5575 PF17738.1 RLN05946.1 - 6e-10 38.6 0.2 1.1e-09 37.7 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5575) Erythro-docking PF09277.11 RLN05946.1 - 0.1 12.5 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 Erythronolide synthase, docking TFIIE-A_C PF11521.8 RLN05947.1 - 0.037 14.3 0.4 0.11 12.8 0.4 1.8 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha LCM PF04072.14 RLN05948.1 - 1.1e-30 107.0 0.0 5.2e-30 104.8 0.0 2.0 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase OrfB_Zn_ribbon PF07282.11 RLN05955.1 - 1.6e-18 66.4 1.6 3.5e-18 65.3 1.6 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 RLN05955.1 - 1e-06 28.9 8.1 0.00031 20.9 8.1 3.0 1 1 0 1 1 1 1 Probable transposase HTH_OrfB_IS605 PF12323.8 RLN05955.1 - 1.1e-06 28.0 0.0 3e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain C1_2 PF03107.16 RLN05955.1 - 0.018 15.3 1.6 0.037 14.3 1.6 1.5 1 0 0 1 1 1 0 C1 domain Tai4 PF16695.5 RLN05955.1 - 0.071 13.6 0.2 0.19 12.3 0.2 1.8 1 0 0 1 1 1 0 Type VI secretion system (T6SS), amidase immunity protein LRR_6 PF13516.6 RLN05980.1 - 6e-05 22.8 7.6 8.8 6.7 0.1 6.1 6 0 0 6 6 6 3 Leucine Rich repeat Suppressor_P21 PF11479.8 RLN05980.1 - 0.013 15.7 0.2 9.6 6.5 0.1 3.3 3 0 0 3 3 3 0 RNA silencing suppressor P21 C-terminal domain MADF_DNA_bdg PF10545.9 RLN05980.1 - 0.091 13.1 0.7 0.24 11.7 0.1 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like LRR_8 PF13855.6 RLN05980.1 - 0.21 11.4 6.5 7 6.5 1.9 4.3 3 1 1 4 4 4 0 Leucine rich repeat DEAD PF00270.29 RLN05983.1 - 3.1e-14 53.1 0.0 1.3e-12 47.9 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN05983.1 - 3.5e-14 53.1 0.0 9.2e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 RLN05983.1 - 1.4e-08 34.9 0.0 1.4e-08 34.9 0.0 3.0 3 0 0 3 3 2 1 Helicase associated domain (HA2) RWD PF05773.22 RLN05983.1 - 7.1e-07 29.5 0.0 1.9e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 RWD domain dsrm PF00035.26 RLN05983.1 - 3.9e-05 24.3 3.1 0.00011 22.8 0.1 2.9 3 0 0 3 3 2 1 Double-stranded RNA binding motif AAA_19 PF13245.6 RLN05983.1 - 0.00022 21.6 0.0 0.00071 19.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain T2SSE PF00437.20 RLN05983.1 - 0.00047 19.3 0.0 0.0014 17.7 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 RLN05983.1 - 0.00076 19.8 0.1 0.0029 17.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain UBA PF00627.31 RLN05983.1 - 0.0031 17.4 0.0 0.62 10.0 0.0 2.8 2 0 0 2 2 2 1 UBA/TS-N domain DnaB_2 PF07261.11 RLN05983.1 - 0.0098 15.6 0.0 0.029 14.1 0.0 1.8 1 0 0 1 1 1 1 Replication initiation and membrane attachment PhoH PF02562.16 RLN05983.1 - 0.019 14.4 0.1 0.048 13.1 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 RLN05983.1 - 0.033 13.9 0.1 0.21 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 RLN05983.1 - 0.041 13.2 0.0 0.094 12.1 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATPase PF06745.13 RLN05983.1 - 0.053 12.9 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 RLN05983.1 - 0.065 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 RLN05983.1 - 0.096 12.3 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 RLN05983.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 RLN05983.1 - 0.11 12.6 0.0 1.8 8.6 0.0 3.0 2 1 0 2 2 2 0 AAA domain DUF4484 PF14831.6 RLN05983.1 - 0.2 11.6 5.3 0.69 9.9 5.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) IATP PF04568.12 RLN05983.1 - 0.46 11.0 5.6 1.2 9.6 1.3 3.1 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP GlyL_C PF12524.8 RLN05983.1 - 0.71 10.0 4.4 2.8 8.1 0.1 2.7 2 0 0 2 2 2 0 dsDNA virus glycoprotein L C terminal AAA_16 PF13191.6 RLN05983.1 - 2.7 8.4 5.2 6.1 7.2 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain FAM163 PF15069.6 RLN05984.1 - 0.0028 18.1 0.3 0.0048 17.4 0.3 1.4 1 1 0 1 1 1 1 FAM163 family zinc-ribbons_6 PF07191.12 RLN05984.1 - 0.045 13.7 1.0 0.045 13.7 1.0 1.5 2 0 0 2 2 2 0 zinc-ribbons Tnp_zf-ribbon_2 PF13842.6 RLN05984.1 - 0.27 12.1 5.1 0.54 11.1 5.1 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon C1_2 PF03107.16 RLN05984.1 - 0.66 10.3 4.2 1.2 9.5 3.5 1.9 1 1 0 1 1 1 0 C1 domain ABC2_membrane PF01061.24 RLN06005.1 - 2e-45 154.8 46.1 3.6e-29 101.7 27.5 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN06005.1 - 2.8e-33 115.3 0.0 1e-16 61.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 RLN06005.1 - 7.9e-07 28.7 0.9 0.0047 16.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN06005.1 - 8.3e-07 29.1 0.3 0.00068 19.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 RLN06005.1 - 9.9e-06 25.9 0.0 0.16 12.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 RLN06005.1 - 5.2e-05 23.2 0.1 2 8.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 RLN06005.1 - 8.8e-05 22.2 0.6 0.3 10.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 RLN06005.1 - 0.00012 22.1 0.1 0.65 10.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 RLN06005.1 - 0.00017 22.1 0.0 0.97 10.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RLN06005.1 - 0.00032 21.3 1.1 0.44 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 RLN06005.1 - 0.00045 20.4 0.0 0.39 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 RLN06005.1 - 0.00074 19.9 0.0 0.99 9.8 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA PF00004.29 RLN06005.1 - 0.00081 19.8 0.6 1.8 9.0 0.0 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 RLN06005.1 - 0.0021 17.8 3.5 0.96 9.1 0.3 2.3 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 RLN06005.1 - 0.0099 16.1 0.4 0.53 10.5 0.2 2.4 2 0 0 2 2 2 1 AAA domain PDR_assoc PF08370.11 RLN06005.1 - 0.017 14.8 0.8 0.017 14.8 0.8 2.4 2 0 0 2 2 2 0 Plant PDR ABC transporter associated RNA_helicase PF00910.22 RLN06005.1 - 0.03 14.7 0.5 13 6.2 0.0 3.1 3 0 0 3 3 3 0 RNA helicase TsaE PF02367.17 RLN06005.1 - 0.036 14.1 1.4 1.3 9.0 0.2 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 RLN06005.1 - 0.039 12.9 0.2 5.8 5.8 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 RLN06005.1 - 0.041 13.1 2.2 4.5 6.5 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 RLN06005.1 - 0.053 13.2 3.6 1.5 8.5 0.2 2.6 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 RLN06005.1 - 0.066 12.8 2.2 5.3 6.6 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 RLN06005.1 - 0.067 13.1 2.4 3.2 7.6 0.4 2.4 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 RLN06005.1 - 0.13 12.6 0.3 6.3 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 RLN06005.1 - 0.15 11.5 0.2 17 4.8 0.0 3.1 2 2 0 2 2 2 0 RecF/RecN/SMC N terminal domain NTPase_1 PF03266.15 RLN06005.1 - 0.17 11.8 2.1 6 6.7 0.0 2.8 3 0 0 3 3 3 0 NTPase AAA_19 PF13245.6 RLN06005.1 - 0.38 11.1 2.3 5 7.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 RLN06005.1 - 3.9 7.5 5.4 18 5.3 0.3 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain HAD PF12710.7 RLN06015.1 - 1.9e-08 34.9 0.0 3.2e-08 34.2 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RLN06015.1 - 1.8e-07 31.7 0.0 4.8e-06 27.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 RLN06015.1 - 0.00019 21.0 0.0 0.00026 20.6 0.0 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.6 RLN06015.1 - 0.12 12.4 0.0 0.23 11.6 0.0 1.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 RLN06015.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF2922 PF11148.8 RLN06015.1 - 0.17 11.6 0.0 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) Sec5 PF15469.6 RLN06016.1 - 8.2e-24 84.5 0.0 6.7e-22 78.2 0.0 2.3 2 0 0 2 2 2 2 Exocyst complex component Sec5 Dor1 PF04124.12 RLN06016.1 - 0.067 11.9 4.7 0.15 10.7 4.7 1.6 1 0 0 1 1 1 0 Dor1-like family Occludin_ELL PF07303.13 RLN06016.1 - 0.14 12.9 0.1 8 7.2 0.0 3.1 3 0 0 3 3 3 0 Occludin homology domain TPR_14 PF13428.6 RLN06017.1 - 3.8e-32 108.2 35.1 0.00022 21.8 0.0 13.4 7 2 9 16 16 13 6 Tetratricopeptide repeat TPR_2 PF07719.17 RLN06017.1 - 2.6e-30 102.1 16.6 0.0027 17.7 0.0 13.0 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_19 PF14559.6 RLN06017.1 - 1.5e-25 89.5 11.1 5.1e-05 23.7 0.1 7.7 6 2 2 8 8 7 7 Tetratricopeptide repeat TPR_16 PF13432.6 RLN06017.1 - 1.3e-19 70.5 32.5 0.00026 21.6 0.9 8.7 6 1 6 12 12 11 7 Tetratricopeptide repeat TPR_17 PF13431.6 RLN06017.1 - 1.5e-19 68.9 1.3 0.066 13.6 0.0 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 RLN06017.1 - 3.4e-17 61.1 0.8 0.018 15.2 0.0 9.3 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN06017.1 - 2.2e-16 59.9 18.4 0.003 17.8 0.0 9.1 4 3 4 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 RLN06017.1 - 1.3e-15 56.9 8.5 1.4 9.7 0.1 11.5 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN06017.1 - 1.7e-12 46.6 10.0 0.01 15.6 0.0 8.6 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN06017.1 - 5.6e-12 45.1 0.2 0.02 14.6 0.0 5.1 5 0 0 5 5 4 3 TPR repeat TPR_9 PF13371.6 RLN06017.1 - 5.8e-12 45.6 17.3 0.0028 17.8 0.8 7.1 4 3 2 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN06017.1 - 7.9e-10 38.8 1.2 0.046 14.0 0.0 4.6 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 RLN06017.1 - 6.6e-07 29.0 2.3 0.0025 17.3 1.0 2.7 1 1 1 2 2 2 2 MalT-like TPR region Suf PF05843.14 RLN06017.1 - 8.4e-07 29.3 0.8 0.063 13.3 0.2 3.2 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_15 PF13429.6 RLN06017.1 - 1.3e-05 24.5 12.9 0.016 14.4 1.6 3.7 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN06017.1 - 0.0016 18.3 11.0 0.92 9.7 0.0 6.1 8 0 0 8 8 5 1 Tetratricopeptide repeat TPR_3 PF07720.12 RLN06017.1 - 0.0069 16.4 0.2 0.078 13.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.8 RLN06017.1 - 0.0091 15.0 5.3 0.25 10.2 0.0 3.8 3 2 2 5 5 5 1 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 RLN06017.1 - 0.083 13.2 8.0 0.45 10.9 0.0 4.2 4 2 1 5 5 4 0 Tetratricopeptide repeat ChAPs PF09295.10 RLN06017.1 - 0.11 11.4 0.3 4.5 6.2 0.0 2.5 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF4611 PF15387.6 RLN06017.1 - 0.22 11.8 1.9 0.42 10.9 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) TPR_10 PF13374.6 RLN06017.1 - 0.49 10.3 17.1 8.7 6.4 0.0 7.0 7 1 0 8 8 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN06017.1 - 0.86 9.7 6.5 77 3.5 0.0 6.0 8 0 0 8 8 7 0 Fis1 C-terminal tetratricopeptide repeat FAT PF02259.23 RLN06017.1 - 0.9 8.7 8.1 10 5.2 0.1 3.5 2 2 1 3 3 3 0 FAT domain SMBP PF16785.5 RLN06017.1 - 0.92 9.8 6.6 1.5 9.1 0.1 4.1 4 0 0 4 4 4 0 Small metal-binding protein TPR_4 PF07721.14 RLN06017.1 - 4.5 8.2 26.6 2.7 8.9 1.1 7.8 9 0 0 9 9 6 0 Tetratricopeptide repeat Ribosomal_L7Ae PF01248.26 RLN06018.1 - 8e-26 89.6 0.4 1.2e-25 89.1 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Dynamin_M PF01031.20 RLN06019.1 - 3.2e-38 131.6 0.0 5.4e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region GED PF02212.18 RLN06019.1 - 1.1e-27 96.0 1.2 2e-27 95.2 1.2 1.4 1 0 0 1 1 1 1 Dynamin GTPase effector domain DUF5600 PF18150.1 RLN06019.1 - 0.074 13.6 0.0 1.1 9.8 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5600) DUF1656 PF07869.12 RLN06020.1 - 0.42 10.7 4.2 0.59 10.2 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) HIG_1_N PF04588.13 RLN06021.1 - 1.1e-16 60.8 1.6 1.6e-16 60.3 1.6 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region WD40 PF00400.32 RLN06022.1 - 3e-11 43.7 8.7 3.6e-05 24.4 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN06022.1 - 7.9e-06 26.1 0.0 1.5 9.2 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Allantoicase PF03561.15 RLN06023.1 - 1.2e-88 294.4 0.0 1.8e-43 148.0 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat Pkinase PF00069.25 RLN06024.1 - 1.7e-53 181.7 0.1 5.4e-53 180.0 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN06024.1 - 1.8e-21 76.6 0.0 2.8e-20 72.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.20 RLN06024.1 - 4.8e-05 23.0 0.1 0.00072 19.2 0.0 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 RLN06024.1 - 0.013 15.5 0.0 0.037 14.0 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family ABC1 PF03109.16 RLN06024.1 - 0.16 12.2 0.1 0.36 11.0 0.1 1.5 1 0 0 1 1 1 0 ABC1 family PAN_1 PF00024.26 RLN06025.1 - 1.2e-06 28.4 4.3 2.2e-06 27.6 4.2 1.5 1 1 0 1 1 1 1 PAN domain PAN_4 PF14295.6 RLN06025.1 - 0.00077 19.3 1.7 0.0017 18.2 1.7 1.5 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 RLN06025.1 - 0.0097 16.0 1.6 0.019 15.1 1.6 1.4 1 0 0 1 1 1 1 PAN-like domain MANEC PF07502.14 RLN06025.1 - 0.016 15.5 1.4 0.037 14.3 1.4 1.6 1 0 0 1 1 1 0 MANEC domain Presenilin PF01080.17 RLN06026.1 - 3.2e-64 217.2 5.0 1e-63 215.5 5.0 1.6 1 1 0 1 1 1 1 Presenilin BaxI_1 PF12811.7 RLN06026.1 - 0.00043 19.9 2.5 0.00043 19.9 2.5 1.4 2 0 0 2 2 2 1 Bax inhibitor 1 like Proteasome PF00227.26 RLN06027.1 - 4.1e-58 196.0 0.1 5.2e-58 195.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RLN06027.1 - 6.1e-14 51.4 0.1 1.2e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3842 PF12953.7 RLN06027.1 - 0.38 11.2 0.2 0.38 11.2 0.2 2.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3842) Synaptobrevin PF00957.21 RLN06028.1 - 5.1e-16 58.2 1.1 9.7e-16 57.3 1.1 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 RLN06028.1 - 3.7e-14 52.5 0.9 6.1e-14 51.8 0.9 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Mid2 PF04478.12 RLN06028.1 - 0.04 13.8 0.1 0.04 13.8 0.1 1.7 3 0 0 3 3 3 0 Mid2 like cell wall stress sensor DUF745 PF05335.13 RLN06028.1 - 5.8 6.6 12.7 12 5.5 5.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) PA PF02225.22 RLN06029.1 - 1.3e-07 31.5 0.0 2.7e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 PA domain DUF640 PF04852.12 RLN06029.1 - 0.0099 16.1 0.1 0.02 15.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF640) Minor_capsid_2 PF11114.8 RLN06029.1 - 0.1 12.6 0.8 0.43 10.6 0.1 2.1 2 0 0 2 2 2 0 Minor capsid protein PTP_tm PF18861.1 RLN06029.1 - 0.11 12.4 0.3 0.22 11.5 0.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Ank_2 PF12796.7 RLN06037.1 - 9.3e-32 109.5 2.7 2.1e-08 34.6 0.2 4.8 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN06037.1 - 6.2e-28 96.8 2.6 7.3e-08 32.8 0.2 6.5 5 1 1 6 6 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN06037.1 - 1.2e-26 92.3 7.4 1.5e-08 34.7 0.0 6.7 3 2 3 6 6 6 6 Ankyrin repeats (many copies) RasGEF PF00617.19 RLN06037.1 - 3e-23 82.9 0.0 7.8e-23 81.6 0.0 1.7 2 0 0 2 2 2 1 RasGEF domain Ank_3 PF13606.6 RLN06037.1 - 5.4e-23 78.6 4.8 0.00059 20.1 0.0 9.1 10 0 0 10 10 9 5 Ankyrin repeat Ank PF00023.30 RLN06037.1 - 7.1e-21 73.7 14.3 0.00025 21.4 0.0 9.3 7 2 0 7 7 7 5 Ankyrin repeat VPS9 PF02204.18 RLN06037.1 - 1.2e-06 28.6 0.0 2.9e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PH PF00169.29 RLN06037.1 - 6.4e-06 26.6 0.0 1.6e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN06037.1 - 0.0013 18.9 0.0 0.087 13.1 0.0 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain EccE PF11203.8 RLN06037.1 - 0.027 14.8 1.6 0.042 14.2 0.1 2.1 2 0 0 2 2 1 0 Putative type VII ESX secretion system translocon, EccE Cwf_Cwc_15 PF04889.12 RLN06037.1 - 0.032 14.0 1.9 0.058 13.1 1.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PDZ PF00595.24 RLN06037.1 - 0.043 14.2 0.0 0.14 12.5 0.0 1.8 2 0 0 2 2 1 0 PDZ domain Dicty_REP PF05086.12 RLN06037.1 - 0.18 9.7 1.0 0.3 9.0 1.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pkinase PF00069.25 RLN06038.1 - 1.4e-55 188.6 0.0 2.1e-55 187.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN06038.1 - 2.7e-29 102.3 0.0 1.8e-28 99.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN06038.1 - 4.3e-05 22.5 0.0 4.3e-05 22.5 0.0 2.4 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 RLN06038.1 - 0.00042 19.7 0.0 0.00099 18.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN06038.1 - 0.00073 19.5 0.1 0.066 13.1 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN06038.1 - 0.017 14.5 0.3 0.033 13.5 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSF_DNA-bind PF00447.17 RLN06040.1 - 6.1e-16 58.8 0.0 9.3e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding DUF2397 PF09660.10 RLN06040.1 - 0.062 12.2 0.3 0.12 11.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) HSF_DNA-bind PF00447.17 RLN06041.1 - 2.2e-15 57.1 0.0 3.5e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding LEAP-2 PF07359.11 RLN06041.1 - 0.21 11.4 0.2 0.41 10.5 0.2 1.5 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) GATase_6 PF13522.6 RLN06052.1 - 1.4e-16 60.9 0.0 6.7e-16 58.7 0.0 2.1 1 1 1 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 RLN06052.1 - 2.6e-16 59.6 0.0 1.6e-15 57.1 0.0 2.3 3 0 0 3 3 3 1 Glutamine amidotransferase domain GATase_4 PF13230.6 RLN06052.1 - 1.2e-09 37.5 0.0 2.5e-09 36.4 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferases class-II Pribosyltran PF00156.27 RLN06052.1 - 6.4e-09 35.5 0.0 1.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PA PF02225.22 RLN06052.1 - 0.053 13.6 0.5 0.18 11.8 0.1 2.0 2 0 0 2 2 2 0 PA domain GDPD PF03009.17 RLN06052.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Baculo_PEP_C PF04513.12 RLN06053.1 - 0.99 9.4 4.9 14 5.8 1.7 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Calx-beta PF03160.14 RLN06054.1 - 3.3e-28 97.8 0.0 3e-07 30.5 0.0 4.8 4 0 0 4 4 4 4 Calx-beta domain TNFR_c6 PF00020.18 RLN06054.1 - 1.5 9.3 18.4 0.15 12.5 2.0 3.4 3 1 0 3 3 3 0 TNFR/NGFR cysteine-rich region Flavoprotein PF02441.19 RLN06055.1 - 9.6e-32 109.9 0.0 1.2e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein BPL_LplA_LipB PF03099.19 RLN06056.1 - 3.2e-11 43.2 0.0 5.2e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family MIX PF18529.1 RLN06056.1 - 0.12 12.1 0.1 0.59 9.8 0.1 1.9 1 1 1 2 2 2 0 Mitochondrial membrane-anchored proteins ADH_N_assoc PF13823.6 RLN06056.1 - 1.8 8.6 4.8 12 6.0 0.4 2.9 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated SNF2_N PF00176.23 RLN06058.1 - 5.4e-53 179.9 0.0 1.3e-52 178.7 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN06058.1 - 4.9e-16 59.1 0.0 1e-15 58.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RLN06058.1 - 2.1e-07 30.9 0.0 4.3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase GREB1 PF15782.5 RLN06058.1 - 0.04 11.1 1.0 0.053 10.7 1.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer HDA2-3 PF11496.8 RLN06058.1 - 0.13 11.4 1.3 0.18 11.0 0.0 1.9 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Nucleo_P87 PF07267.11 RLN06058.1 - 0.25 10.2 10.5 0.38 9.6 10.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NAM PF02365.15 RLN06058.1 - 0.27 12.2 1.5 0.61 11.0 1.5 1.6 1 0 0 1 1 1 0 No apical meristem (NAM) protein Pinin_SDK_memA PF04696.13 RLN06058.1 - 0.68 10.0 14.4 1.4 8.9 14.4 1.5 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region FAM176 PF14851.6 RLN06058.1 - 1.1 9.0 9.8 3.8 7.2 7.6 2.7 3 0 0 3 3 3 0 FAM176 family U1snRNP70_N PF12220.8 RLN06058.1 - 1.4 9.6 11.0 4.1 8.1 11.0 1.8 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Peptidase_C50 PF03568.17 RLN06060.1 - 5e-41 141.1 0.0 3.3e-22 79.2 0.0 2.6 1 1 1 2 2 2 2 Peptidase family C50 Methyltransf_16 PF10294.9 RLN06060.1 - 2.2e-12 47.1 0.0 4.2e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase SAP PF02037.27 RLN06060.1 - 7.8e-07 28.7 0.4 2e-06 27.4 0.4 1.7 1 0 0 1 1 1 1 SAP domain CHAT PF12770.7 RLN06060.1 - 7.6e-05 22.3 0.9 0.00033 20.2 0.1 2.3 2 1 1 3 3 3 1 CHAT domain TPR_2 PF07719.17 RLN06060.1 - 0.083 13.0 0.0 5.2 7.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Fanconi_A_N PF15865.5 RLN06060.1 - 0.1 12.0 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus SLD5_C PF16922.5 RLN06062.1 - 0.094 12.9 0.1 0.16 12.2 0.1 1.4 1 1 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus 2OG-FeII_Oxy_3 PF13640.6 RLN06063.1 - 1.3e-07 32.4 0.0 0.0011 19.8 0.0 2.6 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 RLN06064.1 - 2.4e-63 213.9 0.0 1.6e-62 211.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN06064.1 - 4.7e-29 101.5 0.0 8.7e-29 100.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN06064.1 - 0.00024 20.5 0.0 0.00087 18.7 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RLN06064.1 - 0.019 13.7 0.0 0.042 12.6 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 RLN06064.1 - 0.036 13.4 0.1 0.65 9.3 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN06064.1 - 1.1 9.1 5.4 0.47 10.3 1.3 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family Ank_2 PF12796.7 RLN06065.1 - 2.9e-17 63.0 2.8 2.9e-12 47.0 1.5 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN06065.1 - 2.8e-14 51.8 1.4 0.0046 17.3 0.0 5.0 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 RLN06065.1 - 2e-12 47.0 6.8 0.0028 18.0 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 RLN06065.1 - 2e-11 44.2 2.8 8.1e-06 26.3 0.2 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) EF-hand_1 PF00036.32 RLN06065.1 - 6.7e-11 40.9 0.1 0.0002 20.7 0.0 2.7 2 0 0 2 2 2 2 EF hand Gly_rich PF12810.7 RLN06065.1 - 1.3e-10 41.6 54.0 2.8e-10 40.6 54.0 1.5 1 0 0 1 1 1 1 Glycine rich protein Ank_5 PF13857.6 RLN06065.1 - 3e-10 40.1 2.4 4.4e-05 23.7 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) EF-hand_8 PF13833.6 RLN06065.1 - 1.4e-09 37.7 0.2 1.5e-07 31.1 0.1 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 RLN06065.1 - 6.6e-09 36.1 0.1 2.1e-08 34.5 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN06065.1 - 1.1e-08 34.2 1.0 0.0053 16.2 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN06065.1 - 4.7e-07 29.2 0.1 0.048 13.6 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain WW PF00397.26 RLN06065.1 - 4.4e-06 26.7 2.1 0.2 11.8 0.7 3.9 3 0 0 3 3 3 2 WW domain SUIM_assoc PF16619.5 RLN06065.1 - 2.8 8.1 5.9 9.8 6.3 5.9 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 2OG-FeII_Oxy_3 PF13640.6 RLN06066.1 - 0.00023 22.0 0.0 0.00038 21.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Uricase PF01014.18 RLN06069.1 - 9.8e-54 181.1 0.0 2.6e-26 92.4 0.0 2.9 2 1 0 2 2 2 2 Uricase WD40 PF00400.32 RLN06070.1 - 1.3e-35 120.8 1.6 3.2e-12 46.7 0.4 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN06070.1 - 3.4e-14 52.9 0.0 0.00011 22.4 0.0 3.9 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Katanin_con80 PF13925.6 RLN06070.1 - 8.9e-14 51.8 0.0 1.4e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 con80 domain of Katanin eIF2A PF08662.11 RLN06070.1 - 0.00017 21.5 0.0 0.0029 17.5 0.0 2.6 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 RLN06070.1 - 0.00019 20.3 0.0 2.7 6.6 0.0 3.1 2 1 1 3 3 3 3 Nup133 N terminal like Cytochrom_D1 PF02239.16 RLN06070.1 - 0.00076 18.1 0.1 0.012 14.1 0.1 1.9 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 RLN06070.1 - 0.0017 17.1 0.7 0.013 14.2 0.7 2.2 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RLN06070.1 - 0.0031 16.5 0.2 0.28 10.1 0.2 3.1 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ROS_MUCR PF05443.11 RLN06070.1 - 0.038 14.0 0.0 0.56 10.3 0.0 2.2 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein CLPTM1 PF05602.12 RLN06071.1 - 6.6e-86 289.0 0.0 9.6e-86 288.5 0.0 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) SURF6 PF04935.12 RLN06072.1 - 4.1e-21 75.7 50.6 4.1e-21 75.7 50.6 2.6 1 1 1 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 RLN06072.1 - 8.7e-14 51.9 3.6 8.7e-14 51.9 3.6 6.8 4 2 0 4 4 4 1 60S ribosome biogenesis protein Rrp14 Dynamin_M PF01031.20 RLN06073.1 - 7e-09 35.3 0.0 3.5e-08 33.0 0.0 2.0 1 1 0 1 1 1 1 Dynamin central region GCP_N_terminal PF17681.1 RLN06073.1 - 0.13 11.8 1.8 0.54 9.8 0.1 2.4 2 1 1 3 3 3 0 Gamma tubulin complex component N-terminal G-gamma PF00631.22 RLN06074.1 - 8.7e-12 44.9 0.8 4.7e-11 42.5 0.8 1.8 1 1 0 1 1 1 1 GGL domain Paralemmin PF03285.15 RLN06074.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.0 1 0 0 1 1 1 0 Paralemmin Cation_efflux PF01545.21 RLN06076.1 - 1.4e-27 96.7 3.2 1.8e-27 96.4 3.2 1.2 1 0 0 1 1 1 1 Cation efflux family dDENN PF03455.19 RLN06077.1 - 1.3e-09 37.9 0.5 2.5e-09 37.0 0.5 1.5 1 0 0 1 1 1 1 dDENN domain PDZ_6 PF17820.1 RLN06077.1 - 0.00053 19.8 0.0 0.0014 18.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RLN06077.1 - 0.013 15.9 0.0 0.032 14.6 0.0 1.7 1 0 0 1 1 1 0 PDZ domain DUF3446 PF11928.8 RLN06077.1 - 1.4 9.2 8.8 4.3 7.7 0.4 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain GAF PF01590.26 RLN06090.1 - 3.7e-07 30.8 0.1 1.9e-06 28.5 0.0 2.3 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 RLN06090.1 - 0.00033 21.0 0.2 0.0097 16.3 0.0 3.1 3 0 0 3 3 3 1 GAF domain SHE3 PF17078.5 RLN06090.1 - 0.046 13.4 6.2 0.11 12.2 6.2 1.6 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF4618 PF15397.6 RLN06090.1 - 2.3 7.6 16.1 0.22 10.9 10.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Lyase_8_N PF08124.11 RLN06091.1 - 0.026 13.4 0.1 0.034 13.1 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Pkinase_Tyr PF07714.17 RLN06092.1 - 3.1e-47 161.0 0.0 1.2e-37 129.7 0.0 4.3 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 RLN06092.1 - 6.9e-45 153.5 0.0 5.2e-37 127.6 0.0 3.7 2 1 1 3 3 3 3 Protein kinase domain Pkinase_fungal PF17667.1 RLN06092.1 - 0.014 14.2 0.0 0.095 11.5 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 RLN06092.1 - 1.9 8.3 6.0 0.54 10.1 0.1 3.0 4 0 0 4 4 4 0 Phosphotransferase enzyme family Xpo1 PF08389.12 RLN06093.1 - 1.3e-09 38.2 0.4 3.6e-05 23.9 0.0 3.1 3 0 0 3 3 3 2 Exportin 1-like protein Cpn10 PF00166.21 RLN06094.1 - 1.4e-28 98.8 0.0 1.5e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit GatD_N PF18195.1 RLN06094.1 - 0.036 13.4 0.0 2 7.8 0.0 2.4 1 1 1 2 2 2 0 GatD N-terminal domain DUF2768 PF10966.8 RLN06095.1 - 3.4 8.2 8.3 9.1 6.8 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2768) HA2 PF04408.23 RLN06096.1 - 2.2e-21 76.2 0.0 2.2e-21 76.2 0.0 3.4 4 0 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RLN06096.1 - 7.7e-12 45.4 0.0 1.7e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 RLN06096.1 - 3.3e-11 43.5 0.0 1e-10 41.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RLN06096.1 - 1.7e-07 31.2 0.1 4.1e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RLN06096.1 - 1.5e-05 25.3 0.1 4.5e-05 23.7 0.1 1.8 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 RLN06096.1 - 0.0002 20.7 0.0 0.00045 19.6 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 RLN06096.1 - 0.0006 19.6 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RLN06096.1 - 0.0016 18.8 0.1 0.0038 17.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 RLN06096.1 - 0.0046 16.1 0.0 0.0095 15.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 RLN06096.1 - 0.0048 16.9 0.0 2.5 8.1 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ABC_tran PF00005.27 RLN06096.1 - 0.0058 17.1 0.0 0.019 15.5 0.0 1.9 1 0 0 1 1 1 1 ABC transporter Flavi_DEAD PF07652.14 RLN06096.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_14 PF13173.6 RLN06096.1 - 0.018 15.1 0.1 0.094 12.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RLN06096.1 - 0.032 13.7 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 RLN06096.1 - 0.033 13.5 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 RLN06096.1 - 0.046 13.2 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 RLN06096.1 - 0.054 13.9 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Rhodanese PF00581.20 RLN06096.1 - 0.083 13.4 0.0 0.26 11.8 0.0 1.8 1 0 0 1 1 1 0 Rhodanese-like domain SRP54 PF00448.22 RLN06096.1 - 0.12 11.9 0.2 0.3 10.7 0.2 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 RLN06096.1 - 0.13 12.4 3.1 0.17 12.0 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 RLN06096.1 - 0.13 12.7 0.1 0.13 12.7 0.1 2.4 2 1 1 3 3 2 0 AAA domain Amidohydro_1 PF01979.20 RLN06097.1 - 2.6e-66 224.3 0.0 3.7e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 RLN06097.1 - 1.8e-13 50.8 5.1 3.7e-09 36.6 0.2 2.3 1 1 1 2 2 2 2 Amidohydrolase family Y_phosphatase PF00102.27 RLN06098.1 - 1.2e-07 31.6 0.0 1.5e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 RLN06098.1 - 7.2e-06 25.9 0.0 9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 RLN06098.1 - 0.00049 19.8 0.0 0.0008 19.1 0.0 1.4 1 1 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 RLN06098.1 - 0.0021 18.2 0.0 0.0027 17.8 0.0 1.1 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF1623 PF07785.11 RLN06098.1 - 0.02 15.0 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1623) Mid2 PF04478.12 RLN06098.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Ank_4 PF13637.6 RLN06099.1 - 1e-15 57.9 3.7 1e-06 29.1 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN06099.1 - 2.5e-12 47.2 0.4 7.8e-05 23.2 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN06099.1 - 1.7e-10 40.9 5.0 0.004 17.4 0.1 5.1 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN06099.1 - 9.8e-06 25.6 1.0 5.7 7.8 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 RLN06100.1 - 2e-16 60.3 1.9 0.001 19.6 0.0 5.2 4 1 0 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN06100.1 - 1.2e-13 51.3 5.1 9.5e-07 29.3 0.0 6.8 5 2 1 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN06100.1 - 2.9e-08 33.8 10.8 1.3 9.4 0.9 7.0 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN06100.1 - 5.5e-06 26.3 3.3 75 4.4 0.0 8.2 9 1 1 10 10 10 0 Ankyrin repeat Ank PF00023.30 RLN06100.1 - 0.12 12.9 0.8 1.2e+02 3.4 0.2 4.9 4 1 0 4 4 4 0 Ankyrin repeat SNF2_N PF00176.23 RLN06101.1 - 1.8e-57 194.7 0.0 3.5e-57 193.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF155 PF02582.14 RLN06101.1 - 7.6e-33 114.1 0.9 1.3e-32 113.3 0.9 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Helicase_C PF00271.31 RLN06101.1 - 2.8e-17 63.0 0.0 6.8e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN06101.1 - 3.9e-07 30.2 0.0 7.5e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 RLN06101.1 - 0.0066 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase IL11 PF07400.11 RLN06101.1 - 0.11 12.2 0.1 0.4 10.3 0.1 2.0 1 0 0 1 1 1 0 Interleukin 11 SWIRM-assoc_2 PF16496.5 RLN06101.1 - 3.1 6.6 12.4 6.4 5.5 0.9 2.4 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal GCD14 PF08704.10 RLN06102.1 - 1.7e-79 267.0 0.0 6.2e-79 265.2 0.0 1.7 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 RLN06102.1 - 8.6e-09 35.4 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN06102.1 - 4.9e-07 30.4 0.1 1.8e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN06102.1 - 3e-06 27.8 0.0 9.6e-06 26.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 RLN06102.1 - 8.3e-06 26.8 0.0 2e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 RLN06102.1 - 9.3e-06 25.5 0.4 5.6e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 RLN06102.1 - 0.0002 20.8 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 RLN06102.1 - 0.0008 19.3 0.0 0.0023 17.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 RLN06102.1 - 0.0035 16.5 0.0 0.0059 15.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase GCD14_N PF14801.6 RLN06102.1 - 0.011 15.5 0.0 0.036 13.9 0.0 1.9 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term Methyltr_RsmB-F PF01189.17 RLN06102.1 - 0.014 15.0 0.0 0.07 12.8 0.0 1.9 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F Methyltransf_12 PF08242.12 RLN06102.1 - 0.022 15.5 0.0 0.08 13.7 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.17 RLN06102.1 - 0.064 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin PRTP PF01366.18 RLN06102.1 - 0.2 9.7 0.0 0.28 9.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein ABC_tran PF00005.27 RLN06104.1 - 1.1e-26 94.0 0.0 2.5e-26 92.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN06104.1 - 6.8e-09 35.9 0.3 2.7e-07 30.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 RLN06104.1 - 0.023 13.8 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_15 PF13175.6 RLN06104.1 - 0.076 12.7 0.1 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain FAD_binding_8 PF08022.12 RLN06106.1 - 4.9e-14 52.3 0.0 2.4e-13 50.1 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 RLN06106.1 - 8e-07 29.3 0.0 4e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 RLN06106.1 - 1.4e-06 28.5 6.0 1.4e-06 28.5 6.0 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 RLN06106.1 - 0.014 15.7 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain EF-hand_1 PF00036.32 RLN06107.1 - 1.9e-13 48.9 0.7 1.5e-06 27.3 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN06107.1 - 2.1e-12 45.9 0.4 1.6e-06 27.5 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RLN06107.1 - 3.6e-11 43.3 0.0 9.1e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN06107.1 - 1.2e-09 37.2 2.5 4e-06 26.1 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RLN06107.1 - 7e-08 32.2 0.5 0.0049 16.7 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair zf-TRAF PF02176.18 RLN06107.1 - 0.053 14.2 0.1 0.14 12.9 0.1 1.7 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C4 PF00105.18 RLN06107.1 - 0.067 13.7 0.2 0.067 13.7 0.2 2.3 3 0 0 3 3 3 0 Zinc finger, C4 type (two domains) SrfB PF07520.11 RLN06108.1 - 0.007 14.3 0.0 0.0097 13.8 0.0 1.1 1 0 0 1 1 1 1 Virulence factor SrfB DUF3983 PF13137.6 RLN06130.1 - 0.057 13.2 1.9 0.1 12.4 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) Sybindin PF04099.12 RLN06131.1 - 3.4e-42 143.7 0.1 2.5e-40 137.7 0.1 2.0 1 1 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 RLN06131.1 - 0.0046 17.1 0.0 0.052 13.7 0.0 2.2 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region MORN PF02493.20 RLN06132.1 - 1.2e-48 160.2 44.2 1.7e-07 30.7 0.2 10.2 10 0 0 10 10 10 9 MORN repeat Kelch_3 PF13415.6 RLN06132.1 - 0.0012 19.0 0.6 2.6 8.4 0.1 4.0 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 RLN06132.1 - 0.003 17.5 0.0 2.2 8.4 0.0 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 RLN06132.1 - 0.0053 16.7 0.7 2.8 8.0 0.0 4.0 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.6 RLN06133.1 - 2.4e-09 37.0 1.0 0.25 11.4 0.0 3.5 3 1 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN06133.1 - 7e-07 29.1 0.2 0.12 12.4 0.3 3.5 3 1 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 RLN06133.1 - 1.1e-06 28.6 0.1 0.033 14.5 0.1 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 RLN06133.1 - 8.3e-06 26.0 2.7 0.12 12.7 0.0 3.8 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 RLN06133.1 - 4.3e-05 23.0 1.0 0.11 12.1 0.2 4.0 4 1 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 RLN06133.1 - 0.0002 21.2 0.6 0.66 10.0 0.0 3.3 3 1 0 3 3 3 2 Kelch motif TPR_2 PF07719.17 RLN06134.1 - 4.2e-10 38.9 15.2 0.00092 19.2 0.1 5.0 4 0 0 4 4 4 4 Tetratricopeptide repeat cNMP_binding PF00027.29 RLN06134.1 - 1e-08 35.1 0.1 0.021 14.9 0.0 3.8 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain TPR_1 PF00515.28 RLN06134.1 - 1.3e-07 31.1 9.8 0.015 15.1 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN06134.1 - 2.2e-06 27.4 2.7 0.026 14.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN06134.1 - 0.00016 21.3 0.6 0.022 14.4 0.1 3.1 2 1 1 3 3 3 1 TPR repeat TPR_12 PF13424.6 RLN06134.1 - 0.00017 21.8 12.6 0.088 13.1 3.3 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN06134.1 - 0.007 16.7 3.9 1 9.9 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN06134.1 - 0.11 12.5 0.2 0.44 10.7 0.2 2.1 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 RLN06134.1 - 0.23 11.6 8.8 0.73 10.0 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN06134.1 - 0.32 11.9 15.7 0.27 12.2 1.6 5.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN06134.1 - 0.81 10.4 23.5 0.073 13.7 5.7 4.9 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN06134.1 - 3.4 7.7 9.4 23 5.0 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 RLN06134.1 - 4.1 7.6 12.6 19 5.5 8.7 3.6 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN06134.1 - 7.2 7.5 8.7 6.6 7.6 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat RNase_T PF00929.24 RLN06135.1 - 3.3e-06 27.8 0.0 6.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Exonuclease RRM_1 PF00076.22 RLN06135.1 - 0.004 17.0 0.0 0.012 15.4 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.23 RLN06136.1 - 1e-100 337.0 1.5 1.7e-100 336.2 1.5 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN06136.1 - 1.7e-20 73.5 0.1 5.4e-20 71.8 0.1 1.9 1 0 0 1 1 1 1 Microtubule binding DUF4807 PF16065.5 RLN06136.1 - 0.58 9.8 3.4 2 8.1 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4807) DUF2870 PF11069.8 RLN06136.1 - 8.2 6.9 7.3 1.4 9.4 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2870) Cyclin_N PF00134.23 RLN06137.1 - 2.1e-13 50.1 0.2 3.6e-10 39.7 0.1 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 RLN06137.1 - 0.14 12.2 0.1 0.48 10.5 0.0 1.9 2 0 0 2 2 2 0 Cyclin, C-terminal domain Amino_oxidase PF01593.24 RLN06138.1 - 7.1e-74 249.7 0.0 8.6e-74 249.4 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RLN06138.1 - 3.3e-12 46.5 0.2 6.8e-12 45.4 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 RLN06138.1 - 2.3e-08 34.2 0.7 0.0007 19.6 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 RLN06138.1 - 1.2e-05 25.0 1.3 4.7e-05 23.1 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 RLN06138.1 - 2.5e-05 23.5 3.1 0.019 14.0 0.1 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 RLN06138.1 - 2.8e-05 23.5 0.6 0.0018 17.5 0.5 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RLN06138.1 - 0.001 19.6 0.8 0.005 17.4 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RLN06138.1 - 0.0018 17.7 0.4 0.0027 17.1 0.2 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 RLN06138.1 - 0.0058 15.4 0.8 0.14 10.8 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 RLN06138.1 - 0.0096 15.2 0.0 3.1 6.9 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 RLN06138.1 - 0.012 14.9 0.5 0.022 14.0 0.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MCRA PF06100.11 RLN06138.1 - 0.015 14.2 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 MCRA family Thi4 PF01946.17 RLN06138.1 - 0.024 13.9 0.2 0.044 13.0 0.2 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 RLN06138.1 - 0.044 12.9 4.6 0.037 13.1 2.1 1.9 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 RLN06138.1 - 0.088 12.0 0.5 0.16 11.2 0.5 1.4 1 0 0 1 1 1 0 FAD binding domain Nif11 PF07862.11 RLN06138.1 - 0.11 12.8 0.4 0.4 11.0 0.2 2.0 2 0 0 2 2 1 0 Nif11 domain Trp_halogenase PF04820.14 RLN06138.1 - 0.12 11.2 2.8 0.098 11.5 0.4 1.8 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 RLN06138.1 - 1.9 7.5 5.3 0.43 9.6 1.9 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF1690 PF07956.11 RLN06139.1 - 0.04 14.3 1.0 0.04 14.3 1.0 2.1 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Exonuc_VII_L PF02601.15 RLN06139.1 - 2.1 7.8 8.9 2.9 7.4 8.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PAS_4 PF08448.10 RLN06139.1 - 6.6 7.0 9.2 1.6 9.0 3.8 2.1 1 1 1 2 2 2 0 PAS fold Lipase_GDSL_2 PF13472.6 RLN06140.1 - 1.3e-10 42.0 0.0 5e-10 40.1 0.0 2.1 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family CE2_N PF17996.1 RLN06140.1 - 6.3e-06 26.1 0.3 0.15 12.0 0.0 3.3 2 1 1 3 3 3 2 Carbohydrate esterase 2 N-terminal Lipase_GDSL PF00657.22 RLN06140.1 - 1.2e-05 25.3 0.0 2.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SRX PF09201.10 RLN06140.1 - 0.12 12.1 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 SRX, signal recognition particle receptor alpha subunit AMP-binding PF00501.28 RLN06141.1 - 2.3e-69 234.0 1.6 7.6e-64 215.8 0.0 2.6 2 1 0 3 3 3 2 AMP-binding enzyme AMP-binding_C PF13193.6 RLN06141.1 - 4.3e-15 56.4 2.8 1.1e-14 55.2 0.8 2.9 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Flu_C_NS2 PF03555.14 RLN06141.1 - 0.14 12.3 0.9 8.3 6.7 0.2 2.8 2 0 0 2 2 2 0 Influenza C non-structural protein (NS2) FlaC_arch PF05377.11 RLN06141.1 - 1.4 9.3 3.4 55 4.3 0.3 3.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Shugoshin_N PF07558.11 RLN06141.1 - 9.7 6.2 10.5 11 6.0 2.0 3.9 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Ig_GlcNase PF18368.1 RLN06142.1 - 0.066 13.4 0.4 0.18 12.0 0.2 1.7 2 0 0 2 2 2 0 Exo-beta-D-glucosaminidase Ig-fold domain OKR_DC_1_C PF03711.15 RLN06142.1 - 0.071 13.4 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, C-terminal domain Nucleoside_tran PF01733.18 RLN06143.1 - 1.5e-27 96.8 1.4 2.3e-27 96.2 1.4 1.3 1 0 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 RLN06143.1 - 0.00028 19.9 9.8 0.00028 19.9 9.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3464 PF11947.8 RLN06143.1 - 2.6 7.8 5.2 0.62 9.8 0.8 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 tRNA_int_endo PF01974.17 RLN06144.1 - 3.6e-21 75.0 0.1 6.8e-21 74.1 0.1 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain ATP_transf PF09830.9 RLN06145.1 - 1.5e-15 57.0 0.0 3.6e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 ATP adenylyltransferase Rota_NS6 PF04866.12 RLN06146.1 - 0.013 15.7 0.2 0.022 15.0 0.2 1.3 1 0 0 1 1 1 0 Rotavirus non-structural protein 6 PX PF00787.24 RLN06146.1 - 0.02 14.9 0.1 0.051 13.5 0.1 1.7 1 1 0 1 1 1 0 PX domain HEAT PF02985.22 RLN06156.1 - 3e-14 51.9 3.8 0.81 10.1 0.0 10.2 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.6 RLN06156.1 - 4.3e-10 39.9 12.3 8.3e-09 35.8 0.0 6.9 8 1 1 9 9 9 1 HEAT-like repeat IBN_N PF03810.19 RLN06156.1 - 1e-05 25.3 0.8 0.012 15.5 0.0 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 RLN06156.1 - 1.1e-05 25.8 10.7 0.62 10.5 0.1 6.7 5 2 3 8 8 8 2 HEAT repeats Vac14_Fab1_bd PF12755.7 RLN06156.1 - 0.00012 22.6 0.6 4 8.1 0.0 4.5 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 RLN06156.1 - 0.0098 15.5 0.1 0.41 10.2 0.0 3.6 4 0 0 4 4 4 1 CLASP N terminal Arm PF00514.23 RLN06156.1 - 0.035 14.1 9.9 5.7 7.1 0.0 6.5 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Senescence PF06911.12 RLN06156.1 - 0.056 13.8 0.6 0.32 11.3 0.1 2.5 3 0 0 3 3 3 0 Senescence-associated protein Presenilin PF01080.17 RLN06157.1 - 5.8 5.6 18.2 6.1 5.5 18.2 1.0 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 RLN06157.1 - 6 5.1 12.9 8.1 4.7 12.9 1.2 1 0 0 1 1 1 0 Menin CobT PF06213.12 RLN06157.1 - 9.2 5.6 34.8 11 5.3 34.8 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PAP_assoc PF03828.19 RLN06171.1 - 8.4e-13 48.3 0.0 2.5e-12 46.8 0.0 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 RLN06171.1 - 0.00049 20.3 0.0 0.006 16.9 0.0 2.5 1 1 0 1 1 1 1 Nucleotidyltransferase domain Dus PF01207.17 RLN06172.1 - 2.6e-45 154.9 0.0 3.1e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Dus PF01207.17 RLN06173.1 - 1.6e-11 43.9 0.1 1.9e-11 43.6 0.1 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Ank_2 PF12796.7 RLN06174.1 - 2.5e-33 114.5 10.6 1.3e-12 48.1 0.4 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 RLN06174.1 - 1.7e-25 88.3 13.4 5.1e-05 23.5 0.2 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 RLN06174.1 - 1.3e-24 86.2 4.4 6.1e-09 36.2 0.6 4.7 2 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN06174.1 - 3.1e-22 78.3 13.7 2.3e-07 30.9 0.1 5.8 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN06174.1 - 1.3e-19 68.2 7.2 0.0025 18.2 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Imm_superinfect PF14373.6 RLN06174.1 - 0.011 15.7 0.3 3.8 7.5 0.0 3.4 3 0 0 3 3 3 0 Superinfection immunity protein PEGA PF08308.11 RLN06174.1 - 0.08 12.8 0.0 0.91 9.5 0.0 2.4 3 0 0 3 3 3 0 PEGA domain Dus PF01207.17 RLN06175.1 - 1.4e-47 162.3 0.0 2.3e-47 161.6 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 RLN06175.1 - 0.011 15.2 0.0 0.035 13.6 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein TIM PF00121.18 RLN06175.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Triosephosphate isomerase NAM-associated PF14303.6 RLN06176.1 - 0.013 16.3 1.0 0.077 13.7 0.0 2.6 2 1 1 3 3 3 0 No apical meristem-associated C-terminal domain NAM-associated PF14303.6 RLN06177.1 - 0.038 14.7 0.1 0.038 14.7 0.1 2.0 2 1 0 2 2 2 0 No apical meristem-associated C-terminal domain DUF5308 PF17233.2 RLN06177.1 - 0.097 12.9 5.5 0.045 14.0 1.8 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5308) LRR_6 PF13516.6 RLN06178.1 - 1.8e-11 43.1 0.4 0.039 14.0 0.0 6.1 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 RLN06178.1 - 1.2e-06 28.7 0.0 0.01 16.3 0.0 4.5 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN06178.1 - 0.0013 19.0 0.0 5 8.1 0.0 5.1 6 0 0 6 6 6 1 Leucine Rich Repeat F-box-like PF12937.7 RLN06178.1 - 0.15 12.0 0.2 0.33 10.9 0.2 1.6 1 0 0 1 1 1 0 F-box-like ATPgrasp_ST PF14397.6 RLN06179.1 - 4.6e-12 45.8 0.2 8.1e-11 41.7 0.1 2.6 1 1 1 2 2 2 1 Sugar-transfer associated ATP-grasp LPD3 PF18798.1 RLN06179.1 - 0.034 14.4 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 3 Med27 PF11571.8 RLN06180.1 - 1.7e-20 73.2 2.1 1.8e-20 73.0 2.1 1.0 1 0 0 1 1 1 1 Mediator complex subunit 27 AIB PF15334.6 RLN06181.1 - 0.16 11.3 0.2 0.19 11.0 0.2 1.1 1 0 0 1 1 1 0 Aurora kinase A and ninein interacting protein His_Phos_2 PF00328.22 RLN06182.1 - 8.1e-82 275.6 0.2 6.3e-80 269.4 0.2 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 RLN06182.1 - 7.5e-33 112.6 0.0 1.9e-32 111.3 0.0 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 RLN06182.1 - 3.7e-06 26.7 0.0 7.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain His_Phos_1 PF00300.22 RLN06182.1 - 0.0098 15.6 0.3 0.63 9.7 0.3 3.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) KNOX2 PF03791.13 RLN06182.1 - 0.087 12.3 0.2 0.23 11.0 0.2 1.6 1 0 0 1 1 1 0 KNOX2 domain YabA PF06156.13 RLN06182.1 - 0.47 11.1 3.0 0.52 11.0 0.3 2.3 2 0 0 2 2 2 0 Initiation control protein YabA SWIRM-assoc_1 PF16495.5 RLN06182.1 - 8 6.5 12.7 2.2 8.3 1.8 2.5 2 0 0 2 2 2 0 SWIRM-associated region 1 APG6_N PF17675.1 RLN06182.1 - 8 7.0 7.0 0.75 10.3 0.5 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Glyco_hydro_72 PF03198.14 RLN06189.1 - 1.2e-55 189.0 2.8 1.9e-55 188.4 2.8 1.2 1 0 0 1 1 1 1 Glucanosyltransferase DUF913 PF06025.12 RLN06190.1 - 0.16 10.9 3.1 0.18 10.8 3.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BUD22 PF09073.10 RLN06190.1 - 0.53 9.6 30.8 0.6 9.4 30.8 1.0 1 0 0 1 1 1 0 BUD22 NPR3 PF03666.13 RLN06190.1 - 0.53 9.0 5.0 0.52 9.0 5.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 RLN06190.1 - 0.62 9.2 3.3 0.65 9.1 3.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_polI_A34 PF08208.11 RLN06190.1 - 2.3 8.3 12.3 2.9 7.9 12.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Presenilin PF01080.17 RLN06190.1 - 9.3 4.9 7.2 10 4.7 7.2 1.1 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 RLN06193.1 - 2.4e-05 23.8 0.0 2.8e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain p450 PF00067.22 RLN06194.1 - 6.3e-52 176.8 0.0 8.1e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NMO PF03060.15 RLN06195.1 - 3.4e-61 207.5 0.0 4.9e-61 206.9 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 RLN06195.1 - 4.6e-13 48.9 0.2 7.8e-06 25.1 0.0 2.4 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 RLN06195.1 - 5.1e-05 22.5 2.8 5.6e-05 22.3 0.5 2.1 3 0 0 3 3 3 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 RLN06195.1 - 0.00056 19.4 0.3 0.0012 18.4 0.3 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.21 RLN06195.1 - 0.008 15.4 0.2 0.017 14.4 0.2 1.5 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase DUF561 PF04481.12 RLN06195.1 - 0.024 13.8 0.0 0.17 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF561) ThiG PF05690.14 RLN06195.1 - 0.027 13.8 1.0 0.046 13.0 0.3 1.7 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG 2-Hacid_dh PF00389.30 RLN06195.1 - 0.17 11.5 0.0 0.67 9.6 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ABC_membrane PF00664.23 RLN06196.1 - 3.7e-103 345.0 31.4 4.1e-52 177.5 14.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN06196.1 - 4.1e-72 241.1 0.1 6.6e-36 123.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN06196.1 - 5.4e-13 48.9 2.5 0.00016 21.2 1.6 3.6 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RLN06196.1 - 1.2e-07 32.0 1.7 0.017 15.4 0.1 3.5 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 RLN06196.1 - 1.9e-06 27.9 0.0 0.014 15.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 RLN06196.1 - 3.8e-06 26.6 0.2 0.057 13.2 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 RLN06196.1 - 6.1e-06 25.3 3.2 0.036 12.9 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 RLN06196.1 - 1.9e-05 25.1 2.0 0.16 12.4 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_30 PF13604.6 RLN06196.1 - 0.00028 20.6 1.6 1.2 8.8 0.0 3.7 3 2 0 3 3 3 2 AAA domain SbcCD_C PF13558.6 RLN06196.1 - 0.0004 20.6 4.0 1.4 9.2 0.5 4.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 RLN06196.1 - 0.00071 19.6 1.3 1.7 8.6 0.1 4.0 5 0 0 5 5 3 1 AAA domain (dynein-related subfamily) DEAD PF00270.29 RLN06196.1 - 0.0032 17.2 2.4 0.51 10.1 0.1 3.4 2 2 0 2 2 2 1 DEAD/DEAH box helicase AAA_7 PF12775.7 RLN06196.1 - 0.0034 16.9 0.0 3.4 7.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 RLN06196.1 - 0.0042 16.8 0.9 1.4 8.7 0.0 3.3 4 0 0 4 4 3 1 IstB-like ATP binding protein AAA PF00004.29 RLN06196.1 - 0.0053 17.2 7.1 1.1 9.6 0.1 3.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 RLN06196.1 - 0.0087 16.2 0.1 7.9 6.5 0.0 2.8 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_15 PF13175.6 RLN06196.1 - 0.012 15.4 0.0 0.62 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 RLN06196.1 - 0.014 15.9 0.0 6.3 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 RLN06196.1 - 0.026 13.4 0.0 2.6 6.9 0.0 2.5 2 1 0 2 2 2 0 AAA-like domain APS_kinase PF01583.20 RLN06196.1 - 0.028 14.3 0.1 3.5 7.5 0.0 2.8 2 0 0 2 2 2 0 Adenylylsulphate kinase MoaE PF02391.17 RLN06196.1 - 0.035 14.4 1.7 1.8 8.9 0.2 3.1 2 0 0 2 2 2 0 MoaE protein AAA_24 PF13479.6 RLN06196.1 - 0.082 12.6 0.1 15 5.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 RLN06196.1 - 0.095 11.8 0.0 8.5 5.4 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Rad17 PF03215.15 RLN06196.1 - 0.096 12.6 0.2 0.8 9.6 0.0 2.4 3 0 0 3 3 3 0 Rad17 P-loop domain ATP-synt_ab PF00006.25 RLN06196.1 - 0.14 11.8 0.1 16 5.1 0.0 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 RLN06196.1 - 0.18 12.2 0.1 26 5.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 RLN06196.1 - 0.2 11.9 0.3 23 5.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 RLN06196.1 - 1.4 8.8 3.8 15 5.5 0.0 3.3 4 0 0 4 4 4 0 NTPase MtrB PF05440.12 RLN06196.1 - 7.9 7.0 6.3 29 5.2 0.0 4.4 5 0 0 5 5 4 0 Tetrahydromethanopterin S-methyltransferase subunit B Glycos_transf_1 PF00534.20 RLN06197.1 - 0.00017 21.2 0.0 0.00034 20.2 0.0 1.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RLN06197.1 - 0.00095 19.6 0.0 0.0016 18.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Y_phosphatase2 PF03162.13 RLN06204.1 - 3.1e-17 62.7 0.0 3.4e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family IspD PF01128.19 RLN06204.1 - 0.1 12.3 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase LRR_6 PF13516.6 RLN06205.1 - 0.16 12.1 0.1 5.1 7.4 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeat PH PF00169.29 RLN06208.1 - 3.3e-06 27.5 0.0 6.8e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 PH domain MSA-2c PF12238.8 RLN06208.1 - 0.95 9.4 3.4 1.5 8.7 3.4 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Pkinase PF00069.25 RLN06209.1 - 5.7e-18 65.2 0.3 1.1e-17 64.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN06209.1 - 1.2e-07 31.3 0.1 2.2e-07 30.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase DUF724 PF05266.14 RLN06209.1 - 0.0015 18.4 4.3 0.0021 17.9 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF724) Kdo PF06293.14 RLN06209.1 - 0.084 12.2 1.6 0.43 9.9 0.1 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APG6_N PF17675.1 RLN06209.1 - 0.52 10.8 5.5 0.79 10.3 5.5 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region Menin PF05053.13 RLN06211.1 - 0.002 16.6 7.3 0.0023 16.4 7.3 1.0 1 0 0 1 1 1 1 Menin GREB1 PF15782.5 RLN06211.1 - 5.7 3.9 10.8 6.2 3.8 10.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer GLTP PF08718.11 RLN06212.1 - 6.5e-26 91.4 0.9 1.8e-25 90.0 0.0 1.9 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) zf-AD PF07776.15 RLN06212.1 - 0.052 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) tRNA-synt_1 PF00133.22 RLN06213.1 - 1.5e-143 479.3 0.0 1.8e-143 479.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 RLN06213.1 - 5.3e-28 97.9 0.0 9e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 RLN06213.1 - 3.1e-07 29.5 0.0 0.0047 15.7 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.14 RLN06213.1 - 0.00015 21.6 0.9 0.00031 20.5 0.9 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.6 RLN06213.1 - 0.0005 19.6 0.0 0.0012 18.4 0.0 1.6 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 Adenylsucc_synt PF00709.21 RLN06214.1 - 1.1e-171 571.5 0.0 1.4e-171 571.1 0.0 1.1 1 0 0 1 1 1 1 Adenylosuccinate synthetase TBCA PF02970.16 RLN06215.1 - 1.4e-25 89.4 2.5 1.8e-25 89.1 2.5 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A MMtag PF10159.9 RLN06215.1 - 0.053 13.8 1.2 0.086 13.1 1.2 1.3 1 0 0 1 1 1 0 Multiple myeloma tumor-associated KxDL PF10241.9 RLN06215.1 - 0.066 13.5 1.2 0.16 12.3 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein Ribosomal_S8e PF01201.22 RLN06216.1 - 0.37 11.0 1.9 2.3 8.4 0.5 2.5 2 0 0 2 2 2 0 Ribosomal protein S8e Shugoshin_N PF07558.11 RLN06216.1 - 0.52 10.2 5.4 0.2 11.6 0.2 3.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region APG6_N PF17675.1 RLN06216.1 - 1.9 9.0 79.0 0.067 13.7 15.8 5.7 5 2 1 6 6 6 0 Apg6 coiled-coil region DASH_Dam1 PF08653.10 RLN06216.1 - 3.4 7.5 8.9 3.4 7.6 0.6 4.0 3 0 0 3 3 3 0 DASH complex subunit Dam1 Acyl_transf_3 PF01757.22 RLN06217.1 - 0.0012 18.0 4.4 0.0015 17.6 4.4 1.2 1 0 0 1 1 1 1 Acyltransferase family CHS5_N PF16892.5 RLN06217.1 - 0.011 15.6 0.0 0.031 14.2 0.0 1.7 1 0 0 1 1 1 0 Chitin biosynthesis protein CHS5 N-terminus DUF418 PF04235.12 RLN06217.1 - 0.037 13.9 1.6 0.058 13.3 1.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF418) ABC_membrane PF00664.23 RLN06220.1 - 8.5e-56 189.6 32.0 4.2e-35 121.7 9.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN06220.1 - 1.9e-48 164.5 0.0 1e-26 94.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 RLN06220.1 - 1.5e-06 27.8 0.2 0.032 14.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 RLN06220.1 - 1.7e-06 28.1 0.1 1.3 8.8 0.0 3.6 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 RLN06220.1 - 1.7e-06 28.1 0.1 0.095 12.8 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 RLN06220.1 - 7.7e-06 26.1 0.1 0.00052 20.1 0.0 2.4 2 0 0 2 2 2 1 Dynamin family SMC_N PF02463.19 RLN06220.1 - 1.4e-05 24.6 3.7 1.6 8.1 0.3 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 RLN06220.1 - 0.00025 21.0 0.8 0.27 11.1 0.1 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_23 PF13476.6 RLN06220.1 - 0.00038 21.0 0.5 1.3 9.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 RLN06220.1 - 0.002 17.3 0.1 1.4 8.0 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) DEAD PF00270.29 RLN06220.1 - 0.0066 16.2 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 RLN06220.1 - 0.0066 16.2 0.1 0.13 11.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 RLN06220.1 - 0.017 14.9 0.0 3.9 7.1 0.1 2.6 3 0 0 3 3 3 0 AAA ATPase domain DUF87 PF01935.17 RLN06220.1 - 0.02 15.0 0.2 1 9.4 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain SbcCD_C PF13558.6 RLN06220.1 - 0.024 14.9 0.0 6.6 7.0 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 RLN06220.1 - 0.024 15.0 0.3 1.3 9.4 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 RLN06220.1 - 0.043 13.2 0.1 2.2 7.6 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 RLN06220.1 - 0.055 12.7 0.1 0.75 9.0 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin ABC_membrane_3 PF13748.6 RLN06220.1 - 0.058 12.6 8.1 0.18 11.0 0.1 3.0 2 1 1 3 3 3 0 ABC transporter transmembrane region PepSY_TM PF03929.16 RLN06220.1 - 0.068 12.8 4.2 0.4 10.3 0.5 3.6 3 1 0 3 3 3 0 PepSY-associated TM region Roc PF08477.13 RLN06220.1 - 0.089 13.0 0.1 10 6.4 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 RLN06220.1 - 0.11 11.7 0.2 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 RLN06220.1 - 0.17 12.0 0.0 12 6.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 RLN06220.1 - 0.24 10.9 0.4 11 5.5 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 RLN06220.1 - 0.69 10.2 2.9 28 5.0 0.1 2.9 3 0 0 3 3 2 0 AAA domain ABC_membrane PF00664.23 RLN06221.1 - 1.5e-61 208.5 29.0 1e-35 123.8 6.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN06221.1 - 1.2e-49 168.3 0.0 1.6e-28 100.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN06221.1 - 1.8e-09 37.3 0.2 0.0051 16.3 0.0 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RLN06221.1 - 7.5e-07 29.2 0.0 0.043 13.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 RLN06221.1 - 2.6e-05 24.2 1.3 2.6 7.8 0.0 3.5 3 1 1 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RLN06221.1 - 8.7e-05 23.1 0.0 0.68 10.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 RLN06221.1 - 9.5e-05 22.1 0.3 0.46 10.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 RLN06221.1 - 0.00012 22.2 0.9 0.0066 16.5 0.2 2.4 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 RLN06221.1 - 0.00032 20.7 0.4 0.39 10.6 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 RLN06221.1 - 0.0014 18.3 0.0 0.041 13.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 RLN06221.1 - 0.0022 17.8 0.0 0.016 15.0 0.0 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase Roc PF08477.13 RLN06221.1 - 0.0034 17.6 0.0 3.9 7.7 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 RLN06221.1 - 0.0051 17.4 0.0 3.2 8.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 RLN06221.1 - 0.01 14.8 0.3 0.1 11.5 0.1 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 RLN06221.1 - 0.012 15.3 0.3 0.28 10.7 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 RLN06221.1 - 0.012 15.9 0.1 5.9 7.2 0.0 3.3 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.18 RLN06221.1 - 0.016 14.6 2.4 0.45 9.8 0.1 2.6 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA_16 PF13191.6 RLN06221.1 - 0.032 14.6 0.4 2.6 8.4 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 RLN06221.1 - 0.042 14.0 1.6 0.3 11.1 0.1 2.4 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_30 PF13604.6 RLN06221.1 - 0.043 13.5 0.3 17 5.1 0.1 3.3 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 RLN06221.1 - 0.061 12.4 0.1 0.36 9.8 0.1 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.6 RLN06221.1 - 0.064 13.0 0.1 2.3 7.9 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.14 RLN06221.1 - 0.067 12.4 0.0 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 KAP family P-loop domain DUF815 PF05673.13 RLN06221.1 - 0.089 11.9 0.1 1.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MobB PF03205.14 RLN06221.1 - 0.1 12.5 0.3 2.3 8.1 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 RLN06221.1 - 0.12 12.7 2.2 15 5.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 RLN06221.1 - 0.17 11.6 0.5 7.5 6.3 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 RLN06221.1 - 0.2 11.2 0.2 13 5.2 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 RLN06221.1 - 0.26 11.2 1.2 2.8 7.9 0.0 2.9 3 0 0 3 3 3 0 NACHT domain Ank PF00023.30 RLN06222.1 - 2e-11 43.8 0.3 0.0003 21.1 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 RLN06222.1 - 7e-10 39.2 0.4 3.8e-07 30.5 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN06222.1 - 1.5e-08 35.1 0.0 2.4e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN06222.1 - 7.4e-08 32.5 0.1 0.00098 19.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN06222.1 - 7.8e-06 25.9 0.2 0.0039 17.6 0.1 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ribosomal_L28e PF01778.17 RLN06235.1 - 1.2e-24 87.2 0.0 1.3e-24 87.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family GSHPx PF00255.19 RLN06236.1 - 3.8e-31 106.9 0.1 6e-31 106.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 RLN06236.1 - 0.0019 18.1 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family WXG100 PF06013.12 RLN06237.1 - 0.22 11.8 10.6 1.7 9.0 0.1 3.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG ING PF12998.7 RLN06237.1 - 0.76 10.4 5.7 0.4 11.3 0.6 2.9 2 2 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding RAMA PF18755.1 RLN06238.1 - 1.1e-07 32.2 0.0 6.1e-07 29.8 0.0 2.4 1 1 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated PHD PF00628.29 RLN06238.1 - 1.9e-07 30.8 7.8 4.4e-07 29.7 7.8 1.6 1 0 0 1 1 1 1 PHD-finger DUF1759 PF03564.15 RLN06238.1 - 0.056 13.4 3.2 0.065 13.2 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Zn_ribbon_17 PF17120.5 RLN06238.1 - 0.11 12.1 2.2 0.21 11.2 2.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD_2 PF13831.6 RLN06238.1 - 0.22 11.1 1.1 0.47 10.0 1.1 1.6 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.16 RLN06238.1 - 0.26 11.6 2.0 0.56 10.6 2.0 1.5 1 0 0 1 1 1 0 C1 domain Prok-RING_1 PF14446.6 RLN06238.1 - 1.4 8.9 6.4 3.2 7.8 6.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 FBP_C PF16571.5 RLN06239.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger Helicase_C PF00271.31 RLN06239.1 - 0.076 13.4 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain DUF4804 PF16062.5 RLN06239.1 - 0.13 11.0 0.1 0.21 10.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4804) PH PF00169.29 RLN06262.1 - 7.9e-15 55.3 0.0 1.7e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 RLN06262.1 - 0.024 14.9 0.0 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.6 RLN06262.1 - 0.026 14.9 0.5 0.14 12.5 0.5 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain PI3Ka PF00613.20 RLN06262.1 - 0.08 12.3 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) zf-met PF12874.7 RLN06263.1 - 0.00066 20.0 0.1 0.0016 18.7 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RLN06263.1 - 0.00074 19.7 0.1 0.0017 18.6 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Syntaxin-6_N PF09177.11 RLN06263.1 - 0.0018 18.8 0.7 0.0045 17.5 0.7 1.8 1 1 0 1 1 1 1 Syntaxin 6, N-terminal zf-C2H2_6 PF13912.6 RLN06263.1 - 0.0023 17.9 0.2 0.0054 16.7 0.2 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 RLN06263.1 - 0.032 15.1 0.2 0.1 13.5 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 RLN06263.1 - 0.063 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_9 PF16293.5 RLN06263.1 - 0.069 13.0 0.1 0.23 11.3 0.1 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) FOXP-CC PF16159.5 RLN06263.1 - 0.069 13.8 2.0 0.58 10.8 2.0 2.4 1 1 0 1 1 1 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 RLN06263.1 - 0.085 13.3 0.2 0.21 12.1 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Sugar_tr PF00083.24 RLN06265.1 - 5e-12 45.4 0.4 5.4e-12 45.3 0.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN06265.1 - 0.0057 15.6 1.6 0.0068 15.4 1.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily She9_MDM33 PF05546.11 RLN06265.1 - 0.12 12.1 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 She9 / Mdm33 family CSRNP_N PF16019.5 RLN06266.1 - 0.055 13.4 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Pox_Ag35 PF03286.14 RLN06266.1 - 1.2 8.9 5.0 5.5 6.7 5.0 1.9 1 1 0 1 1 1 0 Pox virus Ag35 surface protein ABC_ATPase PF09818.9 RLN06267.1 - 3.3e-171 570.0 0.0 3.8e-171 569.8 0.0 1.0 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 RLN06267.1 - 0.025 15.1 0.0 0.043 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_pol_Rpb1_1 PF04997.12 RLN06268.1 - 5.6e-85 285.4 0.0 1.2e-84 284.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 RLN06268.1 - 1.8e-76 256.0 0.0 3.4e-76 255.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 RLN06268.1 - 4.6e-38 130.6 0.0 4.3e-37 127.5 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_5 PF04998.17 RLN06268.1 - 1e-31 110.4 0.0 2.2e-31 109.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.17 RLN06268.1 - 1.5e-27 95.6 0.0 3.4e-27 94.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 HSDR_N_2 PF13588.6 RLN06285.1 - 0.0029 17.6 0.2 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) Pkip-1 PF06878.11 RLN06285.1 - 0.0058 16.7 0.5 0.013 15.6 0.4 1.6 2 0 0 2 2 2 1 Pkip-1 protein DUF3914 PF13053.6 RLN06285.1 - 0.045 14.1 0.3 0.11 12.8 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) MMR_HSR1_Xtn PF16897.5 RLN06285.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain p25-alpha PF05517.12 RLN06290.1 - 2e-06 28.1 0.0 4.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 p25-alpha Mcp5_PH PF12814.7 RLN06290.1 - 0.049 13.8 0.1 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology Peptidase_M18 PF02127.15 RLN06291.1 - 3.1e-167 556.8 0.0 3.5e-167 556.6 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 RLN06291.1 - 2.8e-07 29.9 0.4 9.9e-07 28.1 0.4 1.9 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase NADH_dh_m_C1 PF15088.6 RLN06291.1 - 0.015 14.9 0.0 0.063 12.9 0.0 1.9 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial Tctex-1 PF03645.13 RLN06292.1 - 2.1e-06 27.9 0.0 2.6e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Dpy-30 PF05186.13 RLN06293.1 - 3.1e-05 23.6 0.5 6.5e-05 22.5 0.5 1.6 1 1 0 1 1 1 1 Dpy-30 motif Pkinase PF00069.25 RLN06294.1 - 7.5e-57 192.7 0.0 1.2e-56 192.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 RLN06294.1 - 2.6e-49 165.2 0.4 1.2e-18 67.0 0.0 3.7 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 RLN06294.1 - 9.1e-28 97.2 0.0 2.5e-27 95.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN06294.1 - 0.13 11.6 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like PH PF00169.29 RLN06295.1 - 2e-39 134.3 0.0 2.7e-09 37.5 0.0 5.0 5 0 0 5 5 5 4 PH domain PH_11 PF15413.6 RLN06295.1 - 4.9e-17 62.3 15.7 0.0007 20.0 0.7 6.3 5 2 0 5 5 5 4 Pleckstrin homology domain PH_8 PF15409.6 RLN06295.1 - 1.1e-14 54.5 0.3 0.00053 20.2 0.0 4.6 4 0 0 4 4 4 4 Pleckstrin homology domain PH_9 PF15410.6 RLN06295.1 - 0.00098 19.5 0.3 21 5.5 0.0 4.7 4 1 0 4 4 4 1 Pleckstrin homology domain UPRTase PF14681.6 RLN06296.1 - 3.7e-34 118.0 0.1 5.4e-34 117.4 0.1 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 RLN06296.1 - 0.034 13.7 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase domain RT_RNaseH_2 PF17919.1 RLN06296.1 - 0.036 14.1 0.0 0.08 13.0 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase PH PF00169.29 RLN06298.1 - 2.2e-59 198.5 19.3 2.8e-11 43.8 0.0 9.7 7 4 0 7 7 7 7 PH domain PH_11 PF15413.6 RLN06298.1 - 3.1e-34 117.6 29.1 1.1e-07 32.3 0.8 10.3 7 3 0 9 9 9 7 Pleckstrin homology domain PH_8 PF15409.6 RLN06298.1 - 3.1e-32 110.7 8.9 2.1e-06 27.9 0.1 7.6 7 1 0 7 7 7 6 Pleckstrin homology domain PH_9 PF15410.6 RLN06298.1 - 4.8e-05 23.7 4.9 14 6.1 0.0 7.2 6 2 1 7 7 7 1 Pleckstrin homology domain PH_4 PF15404.6 RLN06298.1 - 0.034 13.9 0.4 2.3 8.0 0.0 3.7 5 0 0 5 5 5 0 Pleckstrin homology domain KTSC PF13619.6 RLN06298.1 - 0.067 13.0 0.0 2.1 8.2 0.0 3.1 3 0 0 3 3 3 0 KTSC domain UPRTase PF14681.6 RLN06299.1 - 3e-46 157.5 1.2 5.9e-33 114.1 0.1 2.0 1 1 0 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 RLN06299.1 - 0.09 12.3 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain RT_RNaseH_2 PF17919.1 RLN06299.1 - 0.093 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase ECH_2 PF16113.5 RLN06300.1 - 2.2e-114 382.5 0.1 5.5e-114 381.1 0.1 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 RLN06300.1 - 1.5e-31 109.6 0.5 8.2e-30 103.9 0.0 3.0 3 1 0 3 3 3 2 Enoyl-CoA hydratase/isomerase Med21 PF11221.8 RLN06301.1 - 0.045 14.0 0.9 0.045 14.0 0.9 2.9 2 1 0 2 2 2 0 Subunit 21 of Mediator complex CbbQ_C PF08406.10 RLN06301.1 - 0.27 11.5 0.3 0.27 11.5 0.3 2.4 3 0 0 3 3 3 0 CbbQ/NirQ/NorQ C-terminal Thaumatin PF00314.17 RLN06304.1 - 0.00011 21.9 1.7 0.0097 15.6 1.6 2.9 1 1 1 2 2 2 2 Thaumatin family CcmD PF04995.14 RLN06304.1 - 0.00039 20.4 0.0 0.00079 19.5 0.0 1.4 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) DUF4366 PF14283.6 RLN06304.1 - 1 9.4 10.1 0.07 13.2 1.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) Trypan_PARP PF05887.11 RLN06304.1 - 1.8 8.5 27.1 7.2 6.6 27.1 2.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nucleo_P87 PF07267.11 RLN06304.1 - 5.6 5.7 6.2 8.2 5.2 6.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3040 PF11239.8 RLN06305.1 - 0.076 13.3 0.6 0.12 12.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) LRR_4 PF12799.7 RLN06306.1 - 1.8e-05 25.0 0.6 0.046 14.2 0.4 3.4 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN06306.1 - 0.00043 20.0 2.3 0.22 11.3 0.7 3.2 3 1 1 4 4 4 3 Leucine rich repeat HopW1-1 PF15457.6 RLN06306.1 - 0.064 12.5 0.0 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 Type III T3SS secreted effector HopW1-1/HopPmaA FYVE PF01363.21 RLN06314.1 - 2.1e-13 50.2 14.8 3.8e-13 49.4 14.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger DUSP PF06337.12 RLN06314.1 - 1.4e-11 44.9 0.0 2.7e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 DUSP domain FYVE_2 PF02318.16 RLN06314.1 - 2.4 8.4 10.4 7.6 6.8 10.4 1.9 1 1 0 1 1 1 0 FYVE-type zinc finger CAP_GLY PF01302.25 RLN06315.1 - 3.6e-20 71.7 0.2 7.2e-20 70.8 0.2 1.5 1 0 0 1 1 1 1 CAP-Gly domain DUF3668 PF12416.8 RLN06315.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Cep120 protein Pkinase_Tyr PF07714.17 RLN06316.1 - 3.3e-33 115.1 0.0 4.6e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN06316.1 - 1.1e-27 97.1 0.0 1.5e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 RLN06316.1 - 0.021 14.6 1.3 0.32 10.8 0.1 2.3 2 0 0 2 2 2 0 Leucine rich repeat APH PF01636.23 RLN06316.1 - 0.076 12.9 0.5 0.15 11.9 0.5 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 RLN06316.1 - 0.25 10.4 0.0 0.4 9.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 bZIP_2 PF07716.15 RLN06319.1 - 0.062 13.4 14.0 0.33 11.1 14.0 2.3 1 0 0 1 1 1 0 Basic region leucine zipper Fib_alpha PF08702.10 RLN06319.1 - 0.12 12.6 7.0 0.3 11.3 7.0 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc24 PF08286.11 RLN06319.1 - 0.3 11.4 2.5 0.88 9.8 2.5 1.8 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 MCU PF04678.13 RLN06319.1 - 0.3 11.2 6.4 0.048 13.8 1.7 2.2 1 1 2 3 3 3 0 Mitochondrial calcium uniporter UPF0242 PF06785.11 RLN06319.1 - 0.36 10.9 9.7 0.85 9.7 9.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cep57_MT_bd PF06657.13 RLN06319.1 - 1.4 9.4 8.5 0.089 13.3 0.8 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 bZIP_1 PF00170.21 RLN06319.1 - 1.7 8.8 21.5 0.046 13.8 10.5 2.7 3 0 0 3 3 3 0 bZIP transcription factor bZIP_2 PF07716.15 RLN06320.1 - 0.003 17.6 9.6 0.003 17.6 9.6 3.1 3 1 1 4 4 4 1 Basic region leucine zipper HHH_3 PF12836.7 RLN06320.1 - 0.0082 16.4 0.1 0.021 15.1 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif BORCS6 PF10157.9 RLN06320.1 - 0.7 10.1 4.3 15 5.8 0.2 2.7 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 6 SWIRM PF04433.17 RLN06321.1 - 6.2e-29 100.2 0.0 1.7e-28 98.8 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 RLN06321.1 - 9.2e-13 48.0 6.0 9.2e-13 48.0 6.0 3.7 5 0 0 5 5 4 1 SWIRM-associated region 1 LRR_6 PF13516.6 RLN06321.1 - 1.8e-09 36.9 11.4 0.015 15.3 0.1 7.0 7 0 0 7 7 7 2 Leucine Rich repeat Myb_DNA-binding PF00249.31 RLN06321.1 - 5e-05 23.4 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain LRR_8 PF13855.6 RLN06321.1 - 0.0019 17.9 5.7 1.3 8.9 1.0 4.0 3 2 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 RLN06321.1 - 0.002 18.5 7.8 4.7 7.8 0.1 5.1 5 1 1 6 6 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN06321.1 - 0.0061 16.9 7.9 34 5.5 0.0 6.0 6 0 0 6 6 6 0 Leucine Rich Repeat Myb_DNA-bind_6 PF13921.6 RLN06321.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain UPF0270 PF06794.12 RLN06321.1 - 0.2 11.8 3.9 0.25 11.5 0.7 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0270) L31 PF09784.9 RLN06321.1 - 0.33 11.4 0.9 2.4 8.6 0.3 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 DUF1664 PF07889.12 RLN06321.1 - 6.8 6.7 10.0 1.4 8.9 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) EPO_TPO PF00758.18 RLN06322.1 - 0.11 12.5 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin bZIP_2 PF07716.15 RLN06322.1 - 2.5 8.2 14.7 1.6 8.9 7.9 2.5 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 RLN06322.1 - 6.3 7.0 12.0 6.7 6.9 6.2 2.5 2 0 0 2 2 2 0 bZIP transcription factor Hydrolase_4 PF12146.8 RLN06323.1 - 3.1e-07 29.9 0.0 7e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN06323.1 - 5.4e-07 29.5 0.0 0.00044 20.0 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF915 PF06028.11 RLN06323.1 - 0.0072 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) HWE_HK PF07536.14 RLN06323.1 - 0.17 12.6 0.0 0.36 11.6 0.0 1.5 1 0 0 1 1 1 0 HWE histidine kinase SWIM PF04434.17 RLN06339.1 - 5.4e-07 29.2 0.4 1.6e-06 27.6 0.4 1.9 1 0 0 1 1 1 1 SWIM zinc finger Toxin_17 PF08086.11 RLN06339.1 - 0.055 13.8 1.6 0.12 12.7 1.6 1.5 1 0 0 1 1 1 0 Ergtoxin family DUF2795 PF11387.8 RLN06339.1 - 0.68 10.2 3.1 19 5.6 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2795) NOA36 PF06524.12 RLN06340.1 - 0.26 10.6 4.9 0.32 10.3 4.9 1.2 1 0 0 1 1 1 0 NOA36 protein GATase_5 PF13507.6 RLN06342.1 - 8.7e-100 333.1 0.1 1.2e-99 332.7 0.1 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 RLN06342.1 - 1.3e-14 54.6 0.1 2.4e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain SH3_3 PF08239.11 RLN06343.1 - 2.8e-06 27.5 0.4 1.2 9.5 0.0 4.2 4 0 0 4 4 4 3 Bacterial SH3 domain Presenilin PF01080.17 RLN06343.1 - 4.2 6.0 11.2 2.4 6.8 2.3 2.2 2 0 0 2 2 2 0 Presenilin Cullin_binding PF03556.15 RLN06355.1 - 8.8e-31 106.8 0.1 1.4e-30 106.2 0.1 1.3 1 0 0 1 1 1 1 Cullin binding SAP PF02037.27 RLN06355.1 - 0.00064 19.4 0.1 0.0015 18.2 0.1 1.7 1 0 0 1 1 1 1 SAP domain Serglycin PF04360.12 RLN06356.1 - 0.0089 16.0 1.0 0.0089 16.0 1.0 2.8 3 1 1 4 4 4 1 Serglycin TFIIA PF03153.13 RLN06356.1 - 1.5 8.7 9.8 1.8 8.5 4.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_5_C PF18564.1 RLN06357.1 - 3.2e-19 69.2 0.8 6e-19 68.4 0.8 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 RLN06357.1 - 0.12 11.8 0.0 8.9 5.6 0.0 2.1 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 RLN06358.1 - 1.3e-19 70.5 0.2 4.2e-19 68.9 0.2 1.9 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 RLN06358.1 - 0.053 12.9 0.0 4.9 6.5 0.0 2.2 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Maf1 PF09174.10 RLN06363.1 - 3.7e-55 186.7 0.1 5.2e-55 186.3 0.1 1.2 1 0 0 1 1 1 1 Maf1 regulator PWI PF01480.17 RLN06363.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 1 1 0 1 1 1 0 PWI domain Tup_N PF08581.10 RLN06364.1 - 5.5 7.4 10.7 0.19 12.1 1.6 3.3 2 0 0 2 2 2 0 Tup N-terminal Carn_acyltransf PF00755.20 RLN06365.1 - 1.1e-94 318.2 0.0 1.3e-94 318.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Pkinase PF00069.25 RLN06366.1 - 8.8e-50 169.5 0.1 9e-48 162.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN06366.1 - 1.3e-22 80.4 0.2 6.7e-22 78.0 0.2 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN06366.1 - 0.0015 17.9 0.3 0.003 17.0 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN06366.1 - 0.098 12.0 0.6 0.59 9.4 0.0 2.1 2 1 0 2 2 2 0 Kinase-like PRR18 PF15671.5 RLN06366.1 - 8.2 6.2 11.0 0.92 9.3 2.0 2.2 2 0 0 2 2 2 0 Proline-rich protein family 18 DnaJ_C PF01556.18 RLN06368.1 - 1e-28 100.3 0.0 1.3e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RLN06368.1 - 9.1e-11 41.7 1.3 2.8e-07 30.6 1.3 2.4 1 1 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 RLN06368.1 - 5.6e-09 36.2 7.8 1e-08 35.4 7.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 RLN06368.1 - 0.00042 20.2 3.4 0.00097 19.1 1.0 2.2 2 0 0 2 2 2 1 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 RLN06368.1 - 0.018 15.1 0.5 0.038 14.0 0.5 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 RLN06368.1 - 0.17 11.9 2.2 0.28 11.2 2.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon CMAS PF02353.20 RLN06373.1 - 2e-24 86.4 0.0 4.5e-21 75.4 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 RLN06373.1 - 0.0025 18.5 0.2 0.0068 17.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN06373.1 - 0.006 17.3 0.0 0.012 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN06373.1 - 0.016 15.9 0.0 0.031 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF1700 PF08006.11 RLN06373.1 - 2.5 7.6 6.0 0.63 9.6 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) WW PF00397.26 RLN06374.1 - 2.4e-36 123.5 25.0 1e-09 38.3 4.2 4.5 4 0 0 4 4 4 4 WW domain Glyco_hyd_101C PF17451.2 RLN06374.1 - 7.2e-06 26.3 4.9 1.5 9.1 0.0 4.5 4 0 0 4 4 4 3 Glycosyl hydrolase 101 beta sandwich domain Acyl-CoA_dh_1 PF00441.24 RLN06375.1 - 5.9e-15 55.8 0.0 4.4e-08 33.5 0.0 2.0 1 1 1 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 RLN06375.1 - 8.5e-06 26.1 0.0 0.0013 19.1 0.0 2.1 1 1 1 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain SURF1 PF02104.15 RLN06376.1 - 1.4e-08 35.2 0.0 1.9e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 SURF1 family Bin3 PF06859.12 RLN06377.1 - 1.8e-16 60.7 0.2 4.8e-16 59.3 0.1 1.8 2 0 0 2 2 2 1 Bicoid-interacting protein 3 (Bin3) dsrm PF00035.26 RLN06377.1 - 1.6e-13 51.2 0.0 3.2e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Methyltransf_31 PF13847.6 RLN06377.1 - 8.7e-05 22.4 0.0 0.00031 20.6 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN06377.1 - 0.0017 19.0 0.9 0.022 15.5 0.1 2.9 2 2 0 2 2 2 1 Methyltransferase domain Senescence PF06911.12 RLN06377.1 - 0.0025 18.1 0.3 0.0039 17.5 0.3 1.2 1 0 0 1 1 1 1 Senescence-associated protein Methyltransf_11 PF08241.12 RLN06377.1 - 0.017 15.8 1.0 0.67 10.6 0.1 3.0 2 1 0 2 2 2 0 Methyltransferase domain DUF2202 PF09968.9 RLN06377.1 - 0.04 13.8 0.1 0.063 13.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) Methyltransf_12 PF08242.12 RLN06377.1 - 0.045 14.5 0.1 0.23 12.2 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Cas_Csn2 PF09711.10 RLN06378.1 - 0.066 12.9 0.0 0.076 12.7 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csn2) SBP_bac_6 PF13343.6 RLN06379.1 - 1.9e-14 53.7 0.6 1.9e-10 40.6 0.1 2.2 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 RLN06379.1 - 1.5e-09 38.1 4.7 8.2e-09 35.7 4.7 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 RLN06379.1 - 2.7e-07 30.9 2.0 2.8e-05 24.2 2.0 2.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 RLN06379.1 - 0.0035 17.1 0.2 0.0057 16.4 0.2 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Mistic PF11458.8 RLN06380.1 - 0.013 15.5 0.9 0.027 14.4 0.9 1.5 1 0 0 1 1 1 0 Membrane-integrating protein Mistic DUF3801 PF12687.7 RLN06380.1 - 0.13 12.3 15.4 0.08 13.0 6.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) zf-UBR PF02207.20 RLN06381.1 - 1.1e-17 63.9 14.3 2e-17 63.1 14.3 1.4 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 RLN06381.1 - 2.3e-07 30.5 0.3 6.9e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS Na_H_Exchanger PF00999.21 RLN06382.1 - 3.9e-54 183.9 37.7 4.6e-54 183.7 37.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 RLN06383.1 - 1.1e-49 169.3 41.2 1.3e-49 169.0 41.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family UQ_con PF00179.26 RLN06388.1 - 5.5e-21 74.7 1.4 3.6e-11 42.9 0.3 2.8 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme PRD PF00874.20 RLN06388.1 - 0.029 14.7 0.0 0.041 14.2 0.0 1.2 1 0 0 1 1 1 0 PRD domain BK_channel_a PF03493.18 RLN06389.1 - 2.4e-24 85.4 0.3 1.2e-23 83.1 0.0 2.5 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 RLN06389.1 - 1.3e-12 47.5 12.1 4.4e-12 45.8 12.1 1.8 1 1 0 1 1 1 1 Ion channel LRR_9 PF14580.6 RLN06389.1 - 5e-10 39.1 0.0 1.6e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 Leucine-rich repeat Ion_trans PF00520.31 RLN06389.1 - 1.4e-05 24.5 11.6 2.4e-05 23.7 11.6 1.3 1 0 0 1 1 1 1 Ion transport protein Castor_Poll_mid PF06241.12 RLN06389.1 - 0.0017 18.3 0.0 0.32 11.0 0.0 3.2 3 0 0 3 3 3 1 Castor and Pollux, part of voltage-gated ion channel TrkA_N PF02254.18 RLN06389.1 - 0.0024 18.1 0.0 0.22 11.8 0.0 3.0 2 0 0 2 2 2 1 TrkA-N domain LRR_8 PF13855.6 RLN06389.1 - 0.021 14.6 2.5 0.58 10.0 2.5 2.7 1 1 0 1 1 1 0 Leucine rich repeat Ank_4 PF13637.6 RLN06392.1 - 1.2e-54 181.9 7.6 8.1e-09 35.9 0.0 6.8 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN06392.1 - 1.3e-49 166.6 8.1 5.6e-13 49.3 0.4 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN06392.1 - 2.2e-37 126.6 12.3 1.3e-07 31.7 0.2 7.1 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 RLN06392.1 - 5.4e-34 115.2 11.4 7.6e-05 23.0 0.0 7.5 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 RLN06392.1 - 6.6e-27 90.6 3.4 0.0059 17.0 0.0 8.0 8 0 0 8 8 8 6 Ankyrin repeat Pirin_C_2 PF17954.1 RLN06392.1 - 4.4e-05 23.6 1.0 0.86 9.8 0.0 3.1 1 1 2 3 3 3 2 Quercetinase C-terminal cupin domain SIP PF04954.13 RLN06392.1 - 9.3e-05 22.9 0.1 0.51 10.9 0.0 2.7 1 1 1 2 2 2 2 Siderophore-interacting protein Atu4866 PF11512.8 RLN06392.1 - 0.0009 19.6 0.0 28 5.2 0.0 3.3 3 0 0 3 3 3 0 Agrobacterium tumefaciens protein Atu4866 DUF3952 PF13130.6 RLN06392.1 - 0.0091 16.2 5.1 11 6.3 0.1 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3952) DUF3107 PF11305.8 RLN06392.1 - 0.024 14.9 0.3 79 3.6 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3107) CDPS PF16715.5 RLN06392.1 - 0.029 14.0 0.0 42 3.7 0.0 3.1 3 0 0 3 3 3 0 Cyclodipeptide synthase PK_C PF02887.16 RLN06392.1 - 0.15 12.3 2.9 70 3.7 0.1 3.7 4 0 0 4 4 4 0 Pyruvate kinase, alpha/beta domain Tom37_C PF11801.8 RLN06392.1 - 0.15 12.0 0.1 54 3.7 0.0 2.9 3 0 0 3 3 3 0 Tom37 C-terminal domain Robl_LC7 PF03259.17 RLN06392.1 - 0.17 11.6 3.8 62 3.5 0.1 3.9 1 1 4 5 5 5 0 Roadblock/LC7 domain MFS_1 PF07690.16 RLN06394.1 - 4.2e-13 48.9 11.0 7.3e-07 28.4 1.4 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily YrhC PF14143.6 RLN06394.1 - 0.0095 16.0 5.5 2.6 8.2 0.0 3.8 4 0 0 4 4 4 3 YrhC-like protein zf-LITAF-like PF10601.9 RLN06394.1 - 0.96 9.8 4.2 33 4.8 0.2 3.3 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain NRDE-2 PF08424.10 RLN06395.1 - 6.1e-43 147.2 8.8 2e-41 142.2 8.8 3.1 1 1 0 1 1 1 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 RLN06395.1 - 0.0021 18.7 8.7 2.2 9.3 0.1 6.2 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN06395.1 - 0.0049 17.3 0.3 3.5 8.2 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Suf PF05843.14 RLN06395.1 - 0.48 10.4 9.0 2.5 8.0 0.0 2.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Jacalin PF01419.17 RLN06396.1 - 2.2e-10 40.6 0.0 0.00013 21.9 0.0 2.4 2 0 0 2 2 2 2 Jacalin-like lectin domain zf-A20 PF01754.16 RLN06396.1 - 0.073 13.0 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 A20-like zinc finger AMP-binding PF00501.28 RLN06398.1 - 3.6e-79 266.3 0.0 4.2e-79 266.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN06398.1 - 0.00091 20.2 0.0 0.0021 19.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HR1 PF02185.16 RLN06399.1 - 0.04 14.0 1.5 0.14 12.3 1.5 1.9 1 0 0 1 1 1 0 Hr1 repeat ABC_tran PF00005.27 RLN06400.1 - 4e-27 95.4 0.0 7.5e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN06400.1 - 1.5e-08 34.8 0.3 6.8e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 RLN06400.1 - 2.5e-05 23.5 0.9 2.5e-05 23.5 0.9 1.5 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_15 PF13175.6 RLN06400.1 - 0.037 13.7 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Zn_peptidase_2 PF04298.12 RLN06402.1 - 0.17 11.2 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Pkinase PF00069.25 RLN06403.1 - 4.4e-07 29.5 0.0 8.7e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN06403.1 - 7.2e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-RING_5 PF14634.6 RLN06403.1 - 0.27 11.2 14.8 0.48 10.4 14.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_6 PF14835.6 RLN06403.1 - 2.5 8.0 8.2 2 8.4 3.5 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Mannosyl_trans3 PF11051.8 RLN06437.1 - 2.6e-24 86.0 0.0 3.3e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.8 RLN06438.1 - 4.8e-28 98.3 0.0 6.1e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative Lipase3_N PF03893.16 RLN06438.1 - 0.37 10.8 2.6 2.1 8.4 0.2 2.6 2 0 0 2 2 2 0 Lipase 3 N-terminal region Pkinase_Tyr PF07714.17 RLN06439.1 - 7.4e-27 94.3 0.0 1.5e-26 93.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN06439.1 - 4.7e-24 85.2 0.0 7.2e-23 81.3 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 RLN06439.1 - 0.027 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 RLN06439.1 - 0.037 14.0 2.0 0.061 13.2 0.0 2.3 3 1 1 4 4 4 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 RLN06440.1 - 7.8e-28 97.5 0.0 1.7e-27 96.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RLN06440.1 - 1.4e-26 93.5 0.3 5e-26 91.6 0.0 2.0 3 0 0 3 3 3 1 Protein kinase domain Kinase-like PF14531.6 RLN06440.1 - 0.0043 16.4 0.0 0.008 15.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RLN06440.1 - 0.061 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Mannosyl_trans3 PF11051.8 RLN06441.1 - 1.4e-27 96.8 0.0 1.8e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative AAA_11 PF13086.6 RLN06442.1 - 4.5e-62 210.2 0.7 4.5e-62 210.2 0.7 3.1 2 1 0 2 2 1 1 AAA domain AAA_12 PF13087.6 RLN06442.1 - 7.5e-53 179.1 0.0 1.4e-52 178.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RLN06442.1 - 5.2e-14 52.4 0.2 2.1e-12 47.2 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RLN06442.1 - 8.2e-09 35.9 0.8 7.2e-08 32.9 0.2 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 RLN06442.1 - 1.4e-08 34.8 0.3 0.065 13.0 0.0 3.5 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 RLN06442.1 - 5.9e-08 32.8 5.0 1.6e-06 28.1 0.1 3.6 3 1 0 3 3 3 1 Helicase zf-AN1 PF01428.16 RLN06442.1 - 3.2e-07 30.4 5.2 5.8e-07 29.6 5.2 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger ResIII PF04851.15 RLN06442.1 - 3.8e-06 27.0 0.0 1.3e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RLN06442.1 - 4.9e-05 23.2 2.2 0.00039 20.2 0.1 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase ATPase PF06745.13 RLN06442.1 - 0.00047 19.6 0.0 0.0014 18.0 0.0 1.8 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.6 RLN06442.1 - 0.0015 18.8 1.8 0.0058 16.9 0.0 3.0 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.6 RLN06442.1 - 0.0025 18.2 1.4 0.0078 16.6 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 RLN06442.1 - 0.0097 16.3 0.6 0.038 14.4 0.6 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 RLN06442.1 - 0.0097 15.8 0.1 1.1 9.2 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Flavi_DEAD PF07652.14 RLN06442.1 - 0.011 15.6 1.3 0.12 12.3 0.0 2.7 2 1 0 2 2 2 0 Flavivirus DEAD domain PhoH PF02562.16 RLN06442.1 - 0.013 14.9 0.0 0.047 13.1 0.0 1.9 1 0 0 1 1 1 0 PhoH-like protein UvrD_C PF13361.6 RLN06442.1 - 0.054 12.9 4.7 0.13 11.6 0.1 2.8 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain AAA_25 PF13481.6 RLN06442.1 - 0.062 12.9 2.0 0.34 10.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 RLN06442.1 - 0.1 13.1 0.0 0.1 13.1 0.0 3.2 3 1 0 3 3 2 0 AAA domain REV PF00424.18 RLN06442.1 - 0.16 12.0 1.4 0.81 9.7 0.2 2.8 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) NTPase_1 PF03266.15 RLN06442.1 - 0.26 11.2 3.2 1.9 8.3 0.1 2.5 2 0 0 2 2 2 0 NTPase UQ_con PF00179.26 RLN06443.1 - 1.5e-36 125.2 0.0 2e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RLN06443.1 - 4.6e-06 26.4 0.0 6.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 RLN06443.1 - 0.041 14.2 0.0 0.052 13.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain DDE_1 PF03184.19 RLN06444.1 - 6.6e-19 68.2 0.0 4.5e-17 62.3 0.0 2.3 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN06444.1 - 2.7e-11 43.3 0.1 5.6e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_32 PF13565.6 RLN06444.1 - 0.0098 16.5 1.7 0.043 14.4 0.6 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 RLN06444.1 - 0.029 14.5 0.3 0.29 11.3 0.3 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain CENP-B_N PF04218.13 RLN06444.1 - 0.044 13.4 0.0 0.15 11.7 0.0 1.9 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_29 PF13551.6 RLN06444.1 - 0.05 13.6 0.4 0.05 13.6 0.4 2.5 2 0 0 2 2 2 0 Winged helix-turn helix HTH_11 PF08279.12 RLN06444.1 - 0.07 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 HTH domain Fes1 PF08609.10 RLN06444.1 - 0.1 13.5 1.9 0.43 11.5 0.4 2.7 2 1 0 2 2 2 0 Nucleotide exchange factor Fes1 HTH_Tnp_ISL3 PF13542.6 RLN06444.1 - 0.11 11.9 0.0 0.37 10.2 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 RLN06444.1 - 0.12 12.2 0.3 0.52 10.2 0.3 2.2 1 0 0 1 1 1 0 Homeodomain-like domain SNARE_assoc PF09335.11 RLN06445.1 - 6.2e-13 49.3 2.7 6.2e-13 49.3 2.7 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein WD40 PF00400.32 RLN06447.1 - 2.1e-40 136.0 11.7 1.1e-08 35.5 0.1 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.8 RLN06447.1 - 6.9e-06 25.0 3.9 0.25 9.9 0.0 4.0 2 1 1 3 3 3 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 RLN06447.1 - 5.2e-05 23.5 0.4 1.7 9.0 0.0 3.5 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN06447.1 - 0.015 14.3 0.1 17 4.2 0.0 3.2 1 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 RLN06447.1 - 0.028 13.7 0.0 6.5 6.0 0.0 2.5 2 1 1 3 3 3 0 WD40-like domain Cytochrom_D1 PF02239.16 RLN06447.1 - 0.11 11.0 0.2 0.23 10.0 0.2 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF1272 PF06906.11 RLN06480.1 - 0.017 15.2 3.3 7.4 6.7 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1272) AlphaC_N PF08829.10 RLN06480.1 - 0.028 14.4 0.1 67 3.6 0.0 3.7 3 0 0 3 3 3 0 Alpha C protein N terminal ACPS PF01648.20 RLN06480.1 - 0.12 12.5 0.0 24 5.1 0.0 3.1 3 0 0 3 3 3 0 4'-phosphopantetheinyl transferase superfamily US6 PF17616.2 RLN06480.1 - 1.6 8.6 6.3 2.1 8.3 0.1 3.2 3 0 0 3 3 3 0 Viral unique short region 6 Kazal_1 PF00050.21 RLN06480.1 - 8.2 6.5 21.3 7.5 6.7 0.2 5.4 5 0 0 5 5 5 0 Kazal-type serine protease inhibitor domain adh_short PF00106.25 RLN06481.1 - 7.6e-34 116.9 0.1 1.5e-32 112.7 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN06481.1 - 2.3e-21 76.4 0.1 2.6e-20 73.0 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN06481.1 - 4.2e-09 36.6 0.1 6.1e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN06481.1 - 3.9e-06 26.5 0.1 5.1e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 RLN06481.1 - 0.0069 15.7 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 RLN06482.1 - 1.1e-35 123.5 23.2 8e-34 117.3 23.1 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN06482.1 - 6.2e-32 110.9 23.5 2.5e-29 102.3 21.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 RLN06482.1 - 0.00046 19.6 8.6 0.00046 19.6 8.6 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Tetraspanin PF00335.20 RLN06483.1 - 1e-15 58.1 2.3 1.2e-15 57.9 2.3 1.1 1 0 0 1 1 1 1 Tetraspanin family Thioredoxin_16 PF18569.1 RLN06483.1 - 0.11 12.7 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain DUF4131 PF13567.6 RLN06483.1 - 6.3 6.4 5.7 4.4 6.9 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Pkinase_Tyr PF07714.17 RLN06484.1 - 8.3e-42 143.2 0.0 1.4e-41 142.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN06484.1 - 1.2e-36 126.4 0.0 3e-36 125.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain ABC1 PF03109.16 RLN06484.1 - 0.00027 21.1 0.0 0.00082 19.5 0.0 1.8 1 0 0 1 1 1 1 ABC1 family DZR PF12773.7 RLN06484.1 - 0.0033 17.4 1.0 0.028 14.4 0.2 2.4 2 0 0 2 2 2 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 RLN06484.1 - 0.0049 17.6 0.4 0.034 14.9 0.2 2.3 2 0 0 2 2 2 1 zinc-ribbon family GCSF PF16647.5 RLN06484.1 - 0.11 12.4 0.5 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 Granulocyte colony-stimulating factor zinc_ribbon_2 PF13240.6 RLN06484.1 - 0.16 11.8 2.1 1.3 8.8 2.7 2.2 1 1 1 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 RLN06484.1 - 0.35 10.6 2.8 0.32 10.7 0.3 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.6 RLN06484.1 - 3.6 7.1 5.6 0.73 9.3 1.3 2.1 2 0 0 2 2 2 0 zinc-ribbon domain ABC2_membrane_3 PF12698.7 RLN06486.1 - 1.2e-48 166.0 39.4 1.3e-28 100.2 10.6 3.1 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 RLN06486.1 - 2.3e-27 96.2 0.0 4.2e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN06486.1 - 5e-10 39.7 0.3 2.4e-06 27.6 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RLN06486.1 - 0.0021 18.6 0.0 0.0041 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 RLN06486.1 - 0.0024 17.5 0.3 0.006 16.3 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN06486.1 - 0.0052 16.7 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 RLN06486.1 - 0.049 13.1 0.1 0.74 9.2 0.1 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 RLN06486.1 - 0.11 11.9 0.3 2 7.7 0.2 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_15 PF13175.6 RLN06486.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain ABC2_membrane_2 PF12679.7 RLN06486.1 - 3 7.0 33.5 0.015 14.6 8.3 3.8 3 1 0 3 3 3 0 ABC-2 family transporter protein Porphobil_deam PF01379.20 RLN06493.1 - 2.5e-65 219.8 0.0 3.3e-65 219.4 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain DUF4129 PF13559.6 RLN06493.1 - 0.11 12.7 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) Porphobil_deam PF01379.20 RLN06494.1 - 3.4e-07 30.0 0.1 5.4e-07 29.3 0.1 1.4 1 1 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Sugar_tr PF00083.24 RLN06495.1 - 9.5e-16 57.7 13.5 1.1e-15 57.4 13.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN06495.1 - 4.1e-07 29.3 2.4 4.3e-07 29.2 2.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Pkinase PF00069.25 RLN06497.1 - 0.00085 18.8 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 RLN06497.1 - 0.0062 15.9 0.1 0.015 14.6 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN06497.1 - 0.076 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-RING_2 PF13639.6 RLN06498.1 - 2.1e-11 44.0 8.3 2.1e-11 44.0 8.3 2.6 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 RLN06498.1 - 1.7e-08 34.6 9.0 5.1e-08 33.1 9.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RLN06498.1 - 3.8e-06 26.7 7.7 1.2e-05 25.0 7.7 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN06498.1 - 5.1e-06 26.4 3.3 5.1e-06 26.4 3.3 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RLN06498.1 - 1.1e-05 25.1 10.7 7.2e-05 22.5 10.7 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN06498.1 - 2.4e-05 24.0 8.1 2.4e-05 24.0 8.1 3.3 3 1 0 3 3 3 1 RING-like zinc finger zf-ANAPC11 PF12861.7 RLN06498.1 - 3.6e-05 23.7 1.2 0.0001 22.3 1.2 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RLN06498.1 - 0.00062 19.6 6.0 0.0026 17.6 6.0 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN06498.1 - 0.0029 17.5 6.0 0.0029 17.5 6.0 2.1 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RLN06498.1 - 0.0051 16.7 6.6 0.049 13.5 6.6 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 PX PF00787.24 RLN06498.1 - 0.049 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 PX domain zf-C3HC4_4 PF15227.6 RLN06498.1 - 0.051 13.7 2.9 0.051 13.7 2.9 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 RLN06498.1 - 0.51 10.2 4.9 0.71 9.7 3.8 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 RLN06498.1 - 0.64 10.2 13.0 2.7 8.2 7.9 3.1 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_2 PF13639.6 RLN06499.1 - 1.1e-09 38.4 9.9 1.1e-09 38.4 9.9 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 RLN06499.1 - 2.6e-07 30.8 9.0 9.9e-07 29.0 9.0 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 RLN06499.1 - 9.8e-06 25.5 2.5 9.8e-06 25.5 2.5 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 RLN06499.1 - 2.2e-05 24.2 7.7 6.4e-05 22.7 7.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN06499.1 - 0.00017 21.3 7.4 0.00017 21.3 7.4 2.6 3 1 0 3 3 3 1 RING-like zinc finger zf-RING_UBOX PF13445.6 RLN06499.1 - 0.00045 20.2 4.8 0.00049 20.1 3.0 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RLN06499.1 - 0.0031 17.3 12.6 0.021 14.7 12.6 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN06499.1 - 0.0061 16.4 6.7 0.021 14.7 6.7 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN06499.1 - 0.021 14.8 7.7 0.021 14.8 7.7 2.0 2 0 0 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.8 RLN06499.1 - 0.052 13.7 12.2 0.88 9.8 8.1 3.2 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 RLN06499.1 - 0.71 10.1 8.1 0.11 12.7 2.8 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 RLN06500.1 - 3.3e-08 33.7 15.1 9.8e-07 29.0 15.1 3.0 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RLN06500.1 - 2.4e-06 27.7 11.2 1.1e-05 25.6 11.2 2.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RLN06500.1 - 1.4e-05 24.9 6.9 7.8e-05 22.5 6.9 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 RLN06500.1 - 1.9e-05 24.6 0.0 3.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 PX domain zf-C3HC4_2 PF13923.6 RLN06500.1 - 0.00015 21.5 6.9 0.00015 21.5 6.9 3.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN06500.1 - 0.00042 20.1 9.8 0.05 13.5 9.8 2.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN06500.1 - 0.00065 19.5 9.9 0.0077 16.1 9.9 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 RLN06500.1 - 0.0012 18.9 6.3 0.0041 17.1 5.7 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 RLN06500.1 - 0.0019 17.9 3.4 0.0019 17.9 3.4 3.2 2 1 1 3 3 3 2 RING-like zinc finger zf-ANAPC11 PF12861.7 RLN06500.1 - 0.0058 16.7 5.8 0.0058 16.7 5.8 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 RLN06500.1 - 0.043 13.8 11.1 0.097 12.7 9.3 2.7 2 1 0 2 2 2 0 zinc-RING finger domain Glycolytic PF00274.19 RLN06500.1 - 0.045 12.5 0.0 0.061 12.0 0.0 1.1 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I Ammonium_transp PF00909.21 RLN06521.1 - 3.6e-116 388.1 31.8 4.4e-116 387.9 31.8 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family ADH_zinc_N PF00107.26 RLN06522.1 - 1.7e-06 28.1 0.0 3.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN06522.1 - 0.0001 21.7 0.0 0.00014 21.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN06522.1 - 0.061 12.6 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_N PF08240.12 RLN06523.1 - 9.8e-25 86.6 1.6 9.8e-25 86.6 1.6 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN06523.1 - 3e-16 59.6 0.0 5.2e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN06523.1 - 0.00025 22.1 0.0 0.00055 21.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN06523.1 - 0.0007 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN06523.1 - 0.067 12.5 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AAA PF00004.29 RLN06524.1 - 1.2e-24 87.2 0.2 4.8e-21 75.5 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN06524.1 - 2.5e-06 27.8 1.5 0.00038 20.7 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN06524.1 - 1.5e-05 25.4 1.5 0.0012 19.2 0.1 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 RLN06524.1 - 5.5e-05 23.2 0.1 0.023 14.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 RLN06524.1 - 0.0013 18.7 0.0 0.0038 17.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RLN06524.1 - 0.0018 18.5 0.1 0.12 12.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 RLN06524.1 - 0.0025 17.8 0.0 0.83 9.5 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 RLN06524.1 - 0.0027 17.5 0.0 3.7 7.3 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 RLN06524.1 - 0.0031 17.9 3.1 0.21 11.9 0.2 3.9 4 0 0 4 4 4 1 AAA domain IstB_IS21 PF01695.17 RLN06524.1 - 0.0037 17.0 0.0 3.5 7.3 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 RLN06524.1 - 0.004 17.7 0.2 5.4 7.6 0.1 3.0 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RLN06524.1 - 0.0062 16.1 0.5 0.091 12.3 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 RLN06524.1 - 0.0082 15.9 1.5 1.6 8.4 0.1 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain Zot PF05707.12 RLN06524.1 - 0.0099 15.5 0.1 0.039 13.6 0.0 1.9 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) RNA_helicase PF00910.22 RLN06524.1 - 0.013 15.9 0.0 1.4 9.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 RLN06524.1 - 0.015 15.0 0.0 0.48 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 RLN06524.1 - 0.021 15.0 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) NACHT PF05729.12 RLN06524.1 - 0.039 13.9 0.1 1.2 9.1 0.0 3.2 3 0 0 3 3 3 0 NACHT domain SRP54 PF00448.22 RLN06524.1 - 0.053 13.1 0.1 0.13 11.8 0.1 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 RLN06524.1 - 0.064 13.5 0.8 2 8.6 0.0 3.7 3 0 0 3 3 2 0 AAA domain CbiA PF01656.23 RLN06524.1 - 0.076 13.1 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 RLN06524.1 - 0.078 12.7 1.0 0.45 10.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 RLN06524.1 - 0.082 12.7 0.7 8.8 6.2 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain TIP49 PF06068.13 RLN06524.1 - 0.11 11.7 0.1 6.5 5.8 0.1 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain T2SSE PF00437.20 RLN06524.1 - 0.12 11.4 0.0 0.27 10.2 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 RLN06524.1 - 0.38 10.1 2.2 4.3 6.7 0.3 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 RLN06524.1 - 0.78 9.6 2.5 1.6 8.6 0.0 2.5 3 0 0 3 3 3 0 RsgA GTPase Patched PF02460.18 RLN06534.1 - 5.7e-70 236.4 10.1 5.2e-45 153.8 0.0 2.9 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.8 RLN06534.1 - 1.1e-39 135.7 7.8 1.1e-39 135.7 7.8 3.5 2 2 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation PH PF00169.29 RLN06535.1 - 9.1e-07 29.4 0.0 1.8e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN06535.1 - 0.012 16.0 0.0 0.027 14.9 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain RNase_H PF00075.24 RLN06536.1 - 1.9e-10 41.1 0.0 3.2e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 RLN06536.1 - 0.0019 18.5 0.1 0.0039 17.5 0.1 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin Ank_4 PF13637.6 RLN06536.1 - 0.015 15.9 0.1 0.045 14.4 0.1 1.9 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN06536.1 - 0.023 15.0 0.0 0.16 12.3 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Carn_acyltransf PF00755.20 RLN06537.1 - 1.9e-192 641.0 0.0 2.1e-192 640.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF2542 PF10808.8 RLN06537.1 - 0.01 16.3 2.5 0.023 15.1 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2542) DUF913 PF06025.12 RLN06539.1 - 0.17 10.8 4.0 0.19 10.7 4.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF5094 PF17015.5 RLN06539.1 - 0.31 11.1 7.8 0.45 10.6 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) RRN3 PF05327.11 RLN06539.1 - 5.2 5.5 14.3 6.6 5.1 14.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1488 PF07369.11 RLN06540.1 - 1.9 8.5 8.5 15 5.6 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) Peptidase_C48 PF02902.19 RLN06541.1 - 6.9e-14 52.2 0.3 2.3e-13 50.5 0.3 1.8 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MULE PF10551.9 RLN06541.1 - 3.7e-05 24.1 0.1 0.00012 22.4 0.1 1.9 1 0 0 1 1 1 1 MULE transposase domain Peptidase_C57 PF03290.13 RLN06541.1 - 0.0047 15.7 0.7 0.034 12.9 0.0 2.4 3 0 0 3 3 3 1 Vaccinia virus I7 processing peptidase DDE_Tnp_ISL3 PF01610.17 RLN06541.1 - 5.9 6.5 8.4 0.61 9.8 2.7 2.2 2 1 0 2 2 2 0 Transposase Complex1_LYR PF05347.15 RLN06542.1 - 0.0019 18.2 0.1 0.0019 18.2 0.1 1.9 2 1 0 2 2 2 1 Complex 1 protein (LYR family) efb-c PF12199.8 RLN06544.1 - 0.24 11.5 3.4 9 6.4 1.1 2.5 2 1 0 2 2 2 0 Extracellular fibrinogen binding protein C terminal Pkinase_Tyr PF07714.17 RLN06546.1 - 1.6e-25 89.9 0.0 2.5e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN06546.1 - 6e-25 88.1 0.0 1.2e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 RLN06546.1 - 0.00011 21.8 0.4 0.00037 20.2 0.4 1.8 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 RLN06546.1 - 0.00043 20.6 1.1 0.00043 20.6 1.1 2.6 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) Adeno_E3_CR2 PF02439.15 RLN06546.1 - 0.0034 17.1 0.5 0.0071 16.1 0.5 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 TMEM154 PF15102.6 RLN06546.1 - 0.014 15.3 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family DAP10 PF07213.11 RLN06546.1 - 0.12 12.4 0.2 0.29 11.1 0.2 1.7 1 0 0 1 1 1 0 DAP10 membrane protein Hum_adeno_E3A PF05393.11 RLN06546.1 - 0.13 12.3 0.1 0.81 9.7 0.0 2.2 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Stevor PF17410.2 RLN06546.1 - 0.14 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame RIFIN PF02009.16 RLN06546.1 - 0.23 11.3 0.0 0.4 10.5 0.0 1.3 1 0 0 1 1 1 0 Rifin Peptidase_C48 PF02902.19 RLN06548.1 - 6.2e-12 45.8 0.1 1e-11 45.1 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain LupA PF18242.1 RLN06548.1 - 0.18 11.5 0.0 0.58 9.8 0.0 1.7 1 1 0 1 1 1 0 Legionella ubiquitin-specific protease A domain ABC1 PF03109.16 RLN06549.1 - 8.8e-25 87.2 0.0 1.6e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 RLN06549.1 - 3e-05 23.7 0.3 0.31 10.6 0.0 3.2 2 1 0 3 3 3 2 RIO1 family APH PF01636.23 RLN06549.1 - 0.0074 16.2 0.0 0.029 14.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 RLN06549.1 - 0.11 11.9 0.0 1.9 7.8 0.0 2.4 2 1 0 2 2 2 0 Protein kinase domain CAP PF00188.26 RLN06550.1 - 0.0058 17.5 0.4 0.012 16.4 0.1 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family CAP PF00188.26 RLN06551.1 - 8.1e-19 68.7 4.4 8.1e-19 68.7 4.4 1.5 2 0 0 2 2 2 1 Cysteine-rich secretory protein family MSA-2c PF12238.8 RLN06551.1 - 0.018 15.1 1.4 0.027 14.5 1.4 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Abhydrolase_3 PF07859.13 RLN06560.1 - 2.3e-32 112.6 1.5 6e-28 98.1 0.2 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN06560.1 - 2.3e-11 43.2 0.0 3.6e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 RLN06560.1 - 6e-06 25.9 0.0 1.6e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 RLN06560.1 - 0.06 13.3 0.0 0.23 11.4 0.0 1.9 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal ABC2_membrane PF01061.24 RLN06575.1 - 8.1e-28 97.3 20.8 8.1e-28 97.3 20.8 1.6 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN06575.1 - 0.00074 19.4 0.0 0.0028 17.5 0.0 2.0 1 0 0 1 1 1 1 CDR ABC transporter ABC2_membrane PF01061.24 RLN06576.1 - 4.1e-67 225.7 71.4 2.1e-39 135.1 30.0 3.4 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 RLN06576.1 - 1.9e-34 119.1 0.0 5.3e-16 59.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 RLN06576.1 - 2.8e-08 33.9 0.3 0.0088 16.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 RLN06576.1 - 1e-06 28.8 0.0 0.21 11.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN06576.1 - 7.7e-06 26.4 0.1 0.1 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 RLN06576.1 - 1.1e-05 25.1 5.3 0.05 13.3 1.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN06576.1 - 8.6e-05 23.1 1.4 0.081 13.4 0.7 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RLN06576.1 - 9.4e-05 22.7 0.1 0.34 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain PDR_CDR PF06422.12 RLN06576.1 - 0.00032 20.5 0.2 0.00032 20.5 0.2 3.6 4 0 0 4 4 3 1 CDR ABC transporter AAA_25 PF13481.6 RLN06576.1 - 0.00039 20.1 0.5 0.34 10.4 0.1 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN06576.1 - 0.0012 18.2 0.6 0.26 10.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin DUF87 PF01935.17 RLN06576.1 - 0.015 15.4 5.4 2.2 8.3 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 RLN06576.1 - 0.027 14.5 1.2 7.9 6.6 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 RLN06576.1 - 0.035 14.5 0.3 1.5 9.2 0.1 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 RLN06576.1 - 0.054 12.9 0.3 15 4.9 0.1 3.4 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain PDR_assoc PF08370.11 RLN06576.1 - 0.065 13.0 0.2 0.065 13.0 0.2 5.0 4 1 1 5 5 4 0 Plant PDR ABC transporter associated cobW PF02492.19 RLN06576.1 - 0.079 12.6 2.1 0.4 10.3 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 RLN06576.1 - 0.099 12.4 3.5 5.5 6.7 1.2 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RLN06576.1 - 0.12 12.1 0.2 8.6 6.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 RLN06576.1 - 0.17 11.9 2.2 2.8 7.9 0.6 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 RLN06576.1 - 0.25 11.1 2.4 2.3 8.0 0.5 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 RLN06576.1 - 0.29 11.4 0.5 25 5.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_ATPase PF09818.9 RLN06576.1 - 0.46 9.2 1.7 1.9 7.2 0.9 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NACHT PF05729.12 RLN06576.1 - 0.57 10.1 4.9 7 6.5 0.4 2.5 2 0 0 2 2 2 0 NACHT domain RRP36 PF06102.12 RLN06600.1 - 1.3e-45 155.4 31.5 1.6e-45 155.1 31.5 1.1 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 FAR1 PF03101.15 RLN06601.1 - 0.0039 17.9 0.3 0.0039 17.9 0.3 1.5 2 0 0 2 2 2 1 FAR1 DNA-binding domain Caud_tail_N PF16838.5 RLN06601.1 - 0.061 13.7 0.1 0.47 10.9 0.0 2.1 2 0 0 2 2 2 0 Caudoviral major tail protein N-terminus Viral_NABP PF05515.11 RLN06601.1 - 0.079 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Viral nucleic acid binding Esterase PF00756.20 RLN06602.1 - 1.8e-08 34.3 3.6 1.3e-07 31.5 3.6 2.1 1 1 0 1 1 1 1 Putative esterase Lar_N PF09861.9 RLN06602.1 - 0.0073 15.5 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Lactate racemase N-terminal domain Peptidase_S9 PF00326.21 RLN06602.1 - 0.078 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family MULE PF10551.9 RLN06604.1 - 1.5e-15 57.4 0.3 3.9e-15 56.1 0.3 1.8 1 0 0 1 1 1 1 MULE transposase domain Peptidase_C48 PF02902.19 RLN06604.1 - 9.1e-10 38.7 0.0 2.3e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF5575 PF17738.1 RLN06604.1 - 8.9e-06 25.0 0.0 1.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5575) DDE_Tnp_ISL3 PF01610.17 RLN06604.1 - 0.0048 16.6 0.3 0.014 15.1 0.1 1.9 2 0 0 2 2 2 1 Transposase DUF2811 PF10929.8 RLN06604.1 - 0.08 13.2 0.0 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2811) Sugar_tr PF00083.24 RLN06605.1 - 1e-106 357.5 25.0 1.2e-106 357.3 25.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN06605.1 - 1.1e-27 97.0 53.5 2.5e-25 89.1 26.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily 7TM-7TMR_HD PF07698.11 RLN06605.1 - 0.015 15.1 1.6 0.015 15.1 1.6 3.0 2 1 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Sugar_tr PF00083.24 RLN06606.1 - 2.2e-103 346.5 22.4 2.5e-103 346.3 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN06606.1 - 4.2e-27 95.0 52.1 1.3e-23 83.5 27.3 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily SIN1_PH PF16979.5 RLN06608.1 - 0.0002 21.6 0.3 0.00041 20.6 0.3 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology SRP-alpha_N PF04086.13 RLN06608.1 - 0.064 13.2 4.2 0.098 12.6 4.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CRIM PF16978.5 RLN06608.1 - 0.13 12.4 0.0 0.34 11.1 0.0 1.6 2 0 0 2 2 2 0 SAPK-interacting protein 1 (Sin1), middle CRIM domain DUF4150 PF13665.6 RLN06608.1 - 0.31 11.2 2.4 0.57 10.4 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4150) Ribosomal_L18 PF17135.4 RLN06609.1 - 3.5e-83 277.6 3.0 4.3e-83 277.3 3.0 1.1 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 RLN06609.1 - 0.0065 17.2 0.1 0.015 15.9 0.1 1.8 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A KIAA1430 PF13879.6 RLN06610.1 - 0.00096 19.9 2.0 0.00096 19.9 2.0 5.1 2 2 1 3 3 3 2 KIAA1430 homologue C2 PF00168.30 RLN06610.1 - 0.0028 17.9 0.0 0.0096 16.2 0.0 1.9 2 0 0 2 2 2 1 C2 domain LBR_tudor PF09465.10 RLN06610.1 - 0.09 12.6 1.0 0.19 11.5 1.0 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain DUF948 PF06103.11 RLN06610.1 - 0.28 11.5 4.1 0.51 10.6 2.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) OTU PF02338.19 RLN06612.1 - 3.5e-28 98.7 0.0 3.5e-28 98.7 0.0 2.2 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 RLN06612.1 - 1.3e-06 28.1 2.3 1.5e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Peptidase C65 Otubain Nop25 PF09805.9 RLN06612.1 - 2.6 8.5 19.9 2 8.9 3.5 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) hDGE_amylase PF14701.6 RLN06612.1 - 3.1 6.8 10.7 4.2 6.3 10.7 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain DUF3584 PF12128.8 RLN06612.1 - 6.5 4.1 22.9 8.8 3.7 22.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HAD PF12710.7 RLN06613.1 - 0.0068 16.8 0.3 0.017 15.5 0.3 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NTP_transferase PF00483.23 RLN06614.1 - 6.2e-24 84.9 0.0 8.8e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 RLN06614.1 - 3.4e-08 32.9 9.2 2e-06 27.3 0.3 4.0 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 RLN06614.1 - 0.0036 17.7 0.0 0.007 16.7 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 RLN06614.1 - 0.039 12.1 0.1 0.059 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 RLN06614.1 - 1.4 8.8 3.7 5 7.0 0.1 3.1 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase Pkinase PF00069.25 RLN06615.1 - 7.3e-64 215.7 0.0 1.2e-63 214.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 RLN06615.1 - 9.6e-60 198.7 1.0 4.5e-19 68.3 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 RLN06615.1 - 2.7e-30 105.5 0.0 6.5e-30 104.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 RLN06615.1 - 0.09 12.7 0.0 0.35 10.8 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family SOBP PF15279.6 RLN06616.1 - 1.9 9.0 5.7 2.4 8.7 5.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Sulfotransfer_1 PF00685.27 RLN06617.1 - 2.8e-12 46.7 0.0 4.8e-11 42.6 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Asp_Arg_Hydrox PF05118.15 RLN06617.1 - 4.7e-06 26.5 0.3 9.3e-06 25.5 0.3 1.5 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Sulfotransfer_3 PF13469.6 RLN06617.1 - 7.7e-06 26.4 0.0 0.15 12.4 0.1 3.2 1 1 2 3 3 3 2 Sulfotransferase family DUF4486 PF14858.6 RLN06618.1 - 1.8e-13 49.9 0.0 3.2e-13 49.0 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4486) HTH_Tnp_Tc5 PF03221.16 RLN06620.1 - 0.00081 19.4 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 RLN06620.1 - 0.0033 17.0 0.0 0.011 15.3 0.0 1.9 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 RLN06620.1 - 0.0036 17.4 0.2 0.29 11.3 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_IclR PF09339.10 RLN06620.1 - 0.018 14.8 0.1 0.047 13.5 0.1 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_23 PF13384.6 RLN06620.1 - 0.04 13.7 0.0 0.16 11.8 0.0 2.0 1 0 0 1 1 1 0 Homeodomain-like domain MarR_2 PF12802.7 RLN06620.1 - 0.049 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 RLN06620.1 - 0.058 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Tnp_4 PF13613.6 RLN06620.1 - 0.068 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR PF01047.22 RLN06620.1 - 0.08 12.9 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 MarR family HTH_psq PF05225.16 RLN06620.1 - 0.085 12.6 0.0 0.26 11.1 0.0 1.9 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_Tnp_ISL3 PF13542.6 RLN06620.1 - 0.15 11.5 0.0 0.53 9.7 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 MFS_2 PF13347.6 RLN06636.1 - 1.4e-12 46.9 6.1 1.4e-12 46.9 6.1 2.4 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 RLN06636.1 - 0.098 11.5 10.2 0.57 9.0 5.6 2.4 2 1 0 2 2 2 0 MFS_1 like family DUF5076 PF16826.5 RLN06638.1 - 0.0016 18.4 1.6 0.043 13.7 0.1 3.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5076) Adeno_PIX PF03955.14 RLN06638.1 - 0.37 11.0 3.0 1.4 9.1 3.0 2.0 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) Fez1 PF06818.15 RLN06638.1 - 4.2 7.8 115.7 0.072 13.5 34.9 5.6 2 1 4 6 6 6 0 Fez1 TetR_C_11 PF16859.5 RLN06639.1 - 0.64 10.4 3.7 0.47 10.8 1.0 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Fip1 PF05182.13 RLN06640.1 - 1.6e-23 82.0 0.4 2.8e-23 81.2 0.4 1.4 1 0 0 1 1 1 1 Fip1 motif Sec7 PF01369.20 RLN06641.1 - 3e-56 190.0 0.5 4.8e-56 189.4 0.5 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 RLN06641.1 - 2.8e-13 50.1 0.3 9.4e-12 45.1 0.0 3.3 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Diphthami_syn_2 PF01902.17 RLN06642.1 - 1.9e-13 50.5 0.1 7.9e-13 48.4 0.1 1.9 1 1 0 1 1 1 1 Diphthamide synthase ThiI PF02568.14 RLN06642.1 - 0.079 12.5 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Ribonuc_L-PSP PF01042.21 RLN06643.1 - 5.1e-29 100.7 0.6 9.3e-12 45.0 0.0 4.2 4 0 0 4 4 4 4 Endoribonuclease L-PSP Diphthami_syn_2 PF01902.17 RLN06643.1 - 1.6e-09 37.6 0.0 3.3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Diphthamide synthase Rib_recp_KP_reg PF05104.12 RLN06666.1 - 1.4 10.0 6.9 1.6 9.7 6.9 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Pkinase PF00069.25 RLN06667.1 - 8.4e-50 169.6 0.0 1.2e-49 169.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN06667.1 - 3.3e-49 167.5 0.0 4.6e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Orthoreo_P10 PF07204.11 RLN06667.1 - 2.1e-05 24.4 1.1 6e-05 22.9 1.1 1.7 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 Mid2 PF04478.12 RLN06667.1 - 0.00058 19.7 0.4 0.0015 18.4 0.4 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Shisa PF13908.6 RLN06667.1 - 0.0011 19.3 0.2 0.0011 19.3 0.2 2.0 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 RLN06667.1 - 0.044 13.7 0.9 0.098 12.6 0.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family TMEM51 PF15345.6 RLN06667.1 - 0.049 13.5 0.4 0.098 12.5 0.4 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 EphA2_TM PF14575.6 RLN06667.1 - 0.052 14.4 0.0 0.12 13.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain APH PF01636.23 RLN06667.1 - 0.19 11.6 0.0 0.45 10.4 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family SKG6 PF08693.10 RLN06667.1 - 0.27 10.7 3.3 0.86 9.1 3.3 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4460 PF14687.6 RLN06668.1 - 6.2e-05 23.0 0.0 7.3e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) ATG13 PF10033.9 RLN06669.1 - 2.3e-21 76.6 0.0 2.7e-15 56.7 0.0 2.4 1 1 1 2 2 2 2 Autophagy-related protein 13 Dopey_N PF04118.14 RLN06669.1 - 0.18 10.9 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 Dopey, N-terminal FAD_binding_6 PF00970.24 RLN06670.1 - 1.8e-23 82.8 0.0 3e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 RLN06670.1 - 1.4e-20 73.2 0.0 2.9e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.21 RLN06670.1 - 3.1e-14 53.5 0.0 5.3e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 RLN06670.1 - 9.5e-08 32.3 0.0 4.3e-05 23.7 0.0 2.5 2 1 1 3 3 3 2 Ferric reductase NAD binding domain Oxidored_FMN PF00724.20 RLN06672.1 - 3.7e-71 240.2 0.0 4.6e-71 239.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 RLN06672.1 - 0.018 14.5 0.0 0.098 12.1 0.0 2.1 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Glyco_hydro_61 PF03443.14 RLN06673.1 - 0.007 16.3 0.5 0.059 13.3 0.2 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 VPS9 PF02204.18 RLN06675.1 - 1.7e-15 57.1 0.0 2.9e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PH PF00169.29 RLN06675.1 - 1.1e-11 45.2 0.0 2.2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 PH domain Pex24p PF06398.11 RLN06675.1 - 6.9e-05 22.0 1.7 0.00013 21.1 1.7 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PH_11 PF15413.6 RLN06675.1 - 0.00017 21.9 0.2 0.00047 20.5 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 RLN06675.1 - 0.0011 19.2 0.0 0.0026 18.0 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Mannosyl_trans3 PF11051.8 RLN06677.1 - 7e-20 71.5 0.0 1.1e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.8 RLN06678.1 - 8.6e-26 90.9 0.0 1.1e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative PGM1_C PF18105.1 RLN06679.1 - 0.022 14.3 0.2 0.84 9.2 0.1 3.0 3 0 0 3 3 3 0 PGM1 C-terminal domain Mannosyl_trans3 PF11051.8 RLN06679.1 - 0.19 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Pirin PF02678.16 RLN06680.1 - 6.2e-24 84.1 0.0 1e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 RLN06680.1 - 2.5e-11 43.8 0.0 1.6e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin_C_2 PF17954.1 RLN06680.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 1 0 1 1 1 0 Quercetinase C-terminal cupin domain Ank_2 PF12796.7 RLN06681.1 - 2.1e-186 605.0 26.8 3.5e-20 72.4 0.1 13.4 1 1 10 13 13 13 13 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN06681.1 - 7.2e-156 486.8 21.4 1.2e-05 25.3 0.0 26.7 27 0 0 27 27 27 26 Ankyrin repeat Ank_4 PF13637.6 RLN06681.1 - 8.1e-153 495.0 66.5 1.8e-11 44.3 0.1 20.2 5 4 16 22 22 22 22 Ankyrin repeats (many copies) Ank PF00023.30 RLN06681.1 - 1.6e-151 486.8 33.2 1.2e-07 31.9 0.1 26.1 26 0 0 26 26 26 26 Ankyrin repeat Ank_5 PF13857.6 RLN06681.1 - 4.3e-131 425.3 58.2 5.5e-09 36.1 0.7 24.3 1 1 23 25 25 25 25 Ankyrin repeats (many copies) IlvN PF07991.12 RLN06681.1 - 6e-06 25.9 9.4 12 5.4 0.1 6.8 5 2 2 7 7 7 3 Acetohydroxy acid isomeroreductase, NADPH-binding domain Ldl_recept_b PF00058.17 RLN06681.1 - 0.0003 21.2 1.2 1.9e+02 2.6 0.0 7.5 4 1 5 9 9 8 0 Low-density lipoprotein receptor repeat class B YfmQ PF10787.9 RLN06681.1 - 0.00032 20.5 0.0 42 3.9 0.0 8.2 5 3 6 13 13 13 0 Uncharacterised protein from bacillus cereus group Nepo_coat_C PF03688.14 RLN06681.1 - 0.00079 19.3 5.5 27 4.6 0.0 6.1 4 2 0 6 6 6 0 Nepovirus coat protein, C-terminal domain 3HCDH_RFF PF18321.1 RLN06681.1 - 0.072 13.5 20.8 21 5.7 0.0 9.2 12 1 0 12 12 11 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain SBP_bac_3 PF00497.20 RLN06681.1 - 0.54 9.7 11.9 56 3.0 2.6 6.5 1 1 3 4 4 4 0 Bacterial extracellular solute-binding proteins, family 3 tRNA_NucTran2_2 PF13735.6 RLN06681.1 - 3.6 7.6 10.4 15 5.5 0.1 5.5 3 3 5 8 8 8 0 tRNA nucleotidyltransferase domain 2 putative Pirin PF02678.16 RLN06682.1 - 1.2e-28 99.2 0.0 2.7e-28 98.1 0.0 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 RLN06682.1 - 2.7e-26 91.9 0.1 7e-26 90.6 0.0 1.7 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin_C_2 PF17954.1 RLN06682.1 - 0.022 14.9 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain Pirin PF02678.16 RLN06683.1 - 1.3e-28 99.1 0.0 2.5e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 RLN06683.1 - 2.1e-24 85.9 0.0 9.5e-24 83.8 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin_C_2 PF17954.1 RLN06683.1 - 0.042 14.0 0.0 0.076 13.2 0.0 1.4 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain PX PF00787.24 RLN06685.1 - 6.2e-05 23.0 0.0 0.00019 21.4 0.0 1.8 1 1 0 1 1 1 1 PX domain CSN8_PSD8_EIF3K PF10075.9 RLN06685.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family PLAC9 PF15205.6 RLN06686.1 - 2.2 8.7 5.4 38 4.8 0.9 4.0 3 0 0 3 3 3 0 Placenta-specific protein 9 Pirin PF02678.16 RLN06688.1 - 5.1e-29 100.4 0.0 1.1e-28 99.3 0.0 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 RLN06688.1 - 5.9e-27 94.0 0.1 1.5e-26 92.8 0.0 1.6 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin_C_2 PF17954.1 RLN06688.1 - 0.13 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain Ion_trans PF00520.31 RLN06689.1 - 5e-96 320.7 88.9 1.7e-26 93.0 6.6 4.5 5 0 0 5 5 5 4 Ion transport protein GPHH PF16905.5 RLN06689.1 - 3.6e-10 39.5 0.1 4.7e-09 35.9 0.0 2.5 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 RLN06689.1 - 4.4 5.9 80.6 0.017 13.8 1.0 9.0 6 4 2 9 9 9 0 Polycystin cation channel bZIP_2 PF07716.15 RLN06690.1 - 0.00013 22.0 2.4 0.00022 21.2 2.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 RLN06690.1 - 0.00014 21.9 5.4 0.00022 21.3 5.4 1.2 1 0 0 1 1 1 1 bZIP transcription factor PAS_3 PF08447.12 RLN06690.1 - 0.0033 17.7 0.0 0.0067 16.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 RLN06690.1 - 0.082 12.9 0.1 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 PAS fold Trm56 PF01994.16 RLN06690.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 tRNA ribose 2'-O-methyltransferase, aTrm56 Peroxidase_2 PF01328.17 RLN06691.1 - 1.2e-50 172.7 0.0 1.4e-50 172.4 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 GshA PF08886.11 RLN06691.1 - 0.072 11.7 0.0 0.094 11.3 0.0 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase Carb_anhydrase PF00194.21 RLN06692.1 - 2e-44 152.1 0.0 2.9e-44 151.5 0.0 1.2 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Arb2 PF09757.9 RLN06693.1 - 1.7e-05 24.1 0.0 3.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Arb2 domain Adaptin_binding PF10199.9 RLN06693.1 - 0.0022 18.6 10.1 0.0022 18.6 10.1 3.8 4 2 0 4 4 4 1 Alpha and gamma adaptin binding protein p34 PX PF00787.24 RLN06693.1 - 0.11 12.5 1.6 1.1 9.3 0.0 2.8 3 0 0 3 3 3 0 PX domain WASH-7_N PF14745.6 RLN06693.1 - 0.15 10.5 6.7 0.064 11.8 0.4 2.2 2 0 0 2 2 2 0 WASH complex subunit 7, N-terminal GvpO PF05800.11 RLN06693.1 - 0.9 9.6 5.0 2.4 8.2 3.0 2.9 3 1 0 3 3 3 0 Gas vesicle synthesis protein GvpO Peroxidase_2 PF01328.17 RLN06694.1 - 3.4e-50 171.2 0.0 4.1e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Myb_DNA-binding PF00249.31 RLN06695.1 - 1.1e-11 44.8 0.1 2.4e-11 43.6 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN06695.1 - 0.023 15.0 0.6 0.046 14.0 0.6 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain MAS20 PF02064.15 RLN06695.1 - 1 9.5 4.7 0.4 10.8 0.4 2.1 2 0 0 2 2 2 0 MAS20 protein import receptor zf-C2H2_4 PF13894.6 RLN06765.1 - 0.099 13.5 0.1 0.18 12.8 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 RLN06765.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 RLN06765.1 - 0.14 12.5 0.2 0.16 12.3 0.2 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Radical_SAM_C PF16199.5 RLN06766.1 - 9.4e-21 73.6 0.1 1.9e-20 72.6 0.1 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 RLN06766.1 - 2.8e-14 53.8 1.6 4.8e-14 53.1 0.5 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 RLN06766.1 - 1.2e-07 32.0 0.1 3e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RLN06766.1 - 6.6e-07 29.3 0.1 1.7e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN06766.1 - 0.0047 17.3 0.1 0.012 16.0 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain EccE PF11203.8 RLN06767.1 - 0.43 10.9 2.9 0.57 10.5 1.9 1.7 1 1 1 2 2 2 0 Putative type VII ESX secretion system translocon, EccE Ank_2 PF12796.7 RLN06768.1 - 3.2e-11 43.7 0.3 0.0012 19.4 0.2 3.3 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN06768.1 - 1.5e-08 35.0 2.3 0.026 15.1 0.1 4.4 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN06768.1 - 7.1e-05 23.0 1.2 0.18 12.1 0.0 4.4 3 2 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN06768.1 - 0.15 12.7 1.7 2.3e+02 2.9 0.0 4.7 6 0 0 6 6 6 0 Ankyrin repeat Sulfate_transp PF00916.20 RLN06769.1 - 5.9e-14 51.6 16.1 1.2e-13 50.6 14.5 2.2 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 RLN06769.1 - 3.4e-10 39.6 0.1 7.2e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 RLN06769.1 - 8.5e-05 22.9 18.4 0.031 14.7 5.4 3.1 2 1 1 3 3 3 2 Molybdate transporter of MFS superfamily DUF4407 PF14362.6 RLN06769.1 - 0.044 13.1 0.3 0.085 12.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V-SNARE PF05008.15 RLN06769.1 - 0.12 12.8 3.1 0.097 13.1 0.5 2.0 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus THOC7 PF05615.13 RLN06769.1 - 0.67 10.2 4.6 1.1 9.5 4.6 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 CCDC-167 PF15188.6 RLN06769.1 - 0.75 10.2 3.9 3.1 8.2 3.9 2.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 PMT_4TMC PF16192.5 RLN06769.1 - 0.99 9.0 12.6 0.63 9.6 1.7 2.7 3 0 0 3 3 3 0 C-terminal four TMM region of protein-O-mannosyltransferase TMPIT PF07851.13 RLN06769.1 - 3.2 6.9 6.8 0.65 9.2 0.2 2.3 2 0 0 2 2 2 0 TMPIT-like protein Acetyltransf_10 PF13673.7 RLN06770.1 - 8e-14 51.7 0.0 1e-13 51.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RLN06770.1 - 4e-11 43.2 0.0 4.6e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RLN06770.1 - 5.9e-10 39.4 0.0 7.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 RLN06770.1 - 1.3e-06 28.6 0.1 5.6e-06 26.4 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN06770.1 - 0.00022 21.1 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 RLN06770.1 - 0.04 14.0 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GNAT_acetyltr_2 PF13718.6 RLN06770.1 - 0.067 12.6 0.0 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 GNAT acetyltransferase 2 DUF4605 PF15378.6 RLN06771.1 - 0.037 13.9 0.3 0.065 13.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4605) Pkinase PF00069.25 RLN06772.1 - 1.3e-14 54.2 0.0 1.6e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN06772.1 - 8.1e-06 25.3 0.0 1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN06773.1 - 2.4e-07 30.4 0.0 5.3e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN06773.1 - 0.19 11.0 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase IQ PF00612.27 RLN06823.1 - 0.00025 20.5 0.4 0.00081 19.0 0.4 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Ion_trans PF00520.31 RLN06824.1 - 2.1e-35 122.1 30.7 1.8e-24 86.3 5.8 3.2 2 1 0 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 RLN06824.1 - 9.6e-25 86.4 13.7 2.7e-13 49.7 2.3 2.9 2 0 0 2 2 2 2 Ion channel cNMP_binding PF00027.29 RLN06824.1 - 1.3e-16 60.4 0.2 5.6e-10 39.2 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain IRK PF01007.20 RLN06824.1 - 0.1 12.4 3.6 6.8 6.5 0.3 2.6 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain EF-hand_7 PF13499.6 RLN06825.1 - 8.9e-35 119.0 16.6 1.3e-11 44.8 0.9 4.9 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 RLN06825.1 - 5.4e-29 97.5 17.9 0.00032 20.0 0.9 6.7 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.6 RLN06825.1 - 2.2e-25 86.4 13.1 0.00032 20.4 0.1 7.7 7 0 0 7 7 7 6 EF-hand domain EF-hand_8 PF13833.6 RLN06825.1 - 2.1e-22 78.7 11.5 5.7e-08 32.5 0.2 5.3 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 RLN06825.1 - 1.3e-14 52.9 19.8 0.0025 17.2 0.5 6.7 6 0 0 6 6 6 5 EF hand SPARC_Ca_bdg PF10591.9 RLN06825.1 - 1.4e-07 31.8 13.0 0.0036 17.6 0.2 4.5 3 1 1 4 4 4 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RLN06825.1 - 0.01 15.8 8.5 1.5 8.8 0.0 4.5 2 2 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand Adenine_glyco PF03352.13 RLN06825.1 - 0.028 14.2 0.3 0.1 12.4 0.3 2.0 1 0 0 1 1 1 0 Methyladenine glycosylase SHOCT PF09851.9 RLN06825.1 - 0.64 9.8 3.1 7.1 6.5 0.1 3.3 3 0 0 3 3 3 0 Short C-terminal domain OTU PF02338.19 RLN06826.1 - 0.0019 18.7 0.0 0.0025 18.3 0.0 1.2 1 0 0 1 1 1 1 OTU-like cysteine protease MFS_1 PF07690.16 RLN06827.1 - 6.4e-19 68.1 34.1 6.4e-19 68.1 34.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN06827.1 - 8e-11 41.5 5.7 8e-11 41.5 5.7 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN06828.1 - 1.9e-21 76.4 30.9 1.9e-21 76.4 30.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN06828.1 - 7.9e-11 41.5 4.7 7.9e-11 41.5 4.7 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter DUF4410 PF14366.6 RLN06828.1 - 0.15 12.0 0.3 8.9 6.2 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4410) Glyco_hydro_3_C PF01915.22 RLN06830.1 - 1e-51 175.8 0.0 1.4e-51 175.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RLN06830.1 - 2.8e-07 30.5 0.0 6.4e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PEP_hydrolase PF09370.10 RLN06830.1 - 0.071 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like DDE_1 PF03184.19 RLN06831.1 - 5.6e-13 48.9 0.0 1.1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Phosducin PF02114.16 RLN06831.1 - 0.013 14.5 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosducin RRS1 PF04939.12 RLN06833.1 - 1.7e-50 171.1 4.1 1.7e-50 171.1 4.1 2.3 2 1 1 3 3 3 1 Ribosome biogenesis regulatory protein (RRS1) FYVE PF01363.21 RLN06834.1 - 1e-12 48.0 6.0 1e-12 48.0 6.0 1.7 2 0 0 2 2 2 1 FYVE zinc finger START PF01852.19 RLN06834.1 - 4.8e-06 26.1 0.1 7.7e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 START domain FYVE_2 PF02318.16 RLN06834.1 - 1.3e-05 25.4 1.7 2.8e-05 24.3 1.7 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger HypA PF01155.19 RLN06834.1 - 0.21 11.6 4.5 0.23 11.5 1.5 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_S27e PF01667.17 RLN06834.1 - 2.1 8.1 8.1 0.82 9.4 4.3 2.1 2 0 0 2 2 2 0 Ribosomal protein S27 zf-piccolo PF05715.13 RLN06834.1 - 2.8 8.2 9.1 25 5.1 9.2 2.4 1 1 1 2 2 2 0 Piccolo Zn-finger DZR PF12773.7 RLN06834.1 - 4.3 7.5 9.1 32 4.7 6.3 2.7 2 1 1 3 3 3 0 Double zinc ribbon Coatomer_WDAD PF04053.14 RLN06835.1 - 7.5e-150 499.9 0.0 9.9e-150 499.5 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 RLN06835.1 - 2.3e-11 44.0 2.3 0.00031 21.5 0.0 4.7 4 1 1 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN06835.1 - 0.058 13.7 0.1 8.4 6.8 0.0 4.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIA PF03153.13 RLN06835.1 - 0.075 13.0 21.2 0.1 12.6 21.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ERM PF00769.19 RLN06835.1 - 0.13 12.0 31.2 0.1 12.4 23.8 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF737 PF05300.11 RLN06835.1 - 7.8 6.8 22.7 13 6.1 22.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) GREB1 PF15782.5 RLN06835.1 - 9.1 3.2 13.3 12 2.8 13.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2807 PF10988.8 RLN06835.1 - 9.4 6.0 12.1 7.8 6.2 9.1 2.3 1 1 1 2 2 2 0 Putative auto-transporter adhesin, head GIN domain Clat_adaptor_s PF01217.20 RLN06836.1 - 1.8e-51 173.8 0.7 2e-51 173.6 0.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain NUFIP1 PF10453.9 RLN06837.1 - 5.3e-08 32.6 0.0 1.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCHC_2 PF13696.6 RLN06837.1 - 3.1e-06 26.9 11.2 6.1e-06 25.9 11.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCCH_4 PF18044.1 RLN06837.1 - 2.4e-05 24.0 11.2 0.011 15.5 3.2 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 RLN06837.1 - 0.00061 19.7 11.3 0.001 19.0 1.2 3.1 2 1 0 2 2 2 1 Zinc finger domain zf-C2H2 PF00096.26 RLN06837.1 - 0.0016 18.8 0.3 0.0016 18.8 0.3 2.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-CCHC_3 PF13917.6 RLN06837.1 - 0.0029 17.6 2.3 0.0093 15.9 2.3 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCCH PF00642.24 RLN06837.1 - 0.0035 17.2 13.6 0.059 13.3 2.2 2.9 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.23 RLN06837.1 - 0.014 15.4 4.4 0.014 15.4 4.4 2.1 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_jaz PF12171.8 RLN06837.1 - 0.021 15.1 2.0 0.047 14.0 2.0 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Torus PF16131.5 RLN06837.1 - 0.064 14.0 1.8 0.14 12.8 1.8 1.6 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 RLN06837.1 - 0.88 10.1 10.1 2.1 8.9 0.7 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Ubiquitin_4 PF18036.1 RLN06842.1 - 0.11 12.5 0.8 0.56 10.3 0.8 2.0 1 1 0 1 1 1 0 Ubiquitin-like domain Abhydro_lipase PF04083.16 RLN06843.1 - 6.2e-21 73.7 0.0 1.2e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 RLN06843.1 - 6e-11 42.5 0.1 2.9e-10 40.2 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN06843.1 - 0.004 16.5 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LRR_6 PF13516.6 RLN06844.1 - 1.4e-06 27.8 7.4 3.1 8.1 0.1 5.8 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 RLN06844.1 - 0.015 15.7 3.4 0.58 10.7 0.2 3.7 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN06844.1 - 0.29 10.9 10.5 0.082 12.7 1.5 4.0 3 1 0 3 3 3 0 Leucine rich repeat zinc_ribbon_16 PF17034.5 RLN06845.1 - 5.7e-18 65.3 20.6 1.1e-13 51.5 7.5 3.0 3 0 0 3 3 3 2 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 RLN06845.1 - 0.076 12.6 15.6 0.029 14.0 11.8 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PNPase_C PF12111.8 RLN06846.1 - 0.011 15.1 0.3 0.023 14.1 0.3 1.5 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal bZIP_2 PF07716.15 RLN06848.1 - 3.7e-05 23.7 29.9 0.0013 18.8 8.9 3.8 4 0 0 4 4 4 2 Basic region leucine zipper bZIP_1 PF00170.21 RLN06848.1 - 0.0029 17.6 4.5 0.0029 17.6 4.5 3.5 4 0 0 4 4 4 2 bZIP transcription factor Adeno_E1A PF02703.14 RLN06848.1 - 0.1 12.2 0.7 1.7 8.2 0.1 2.3 2 1 0 2 2 2 0 Early E1A protein OrfB_IS605 PF01385.19 RLN06848.1 - 2.1 8.6 8.1 2 8.6 1.7 2.4 2 0 0 2 2 2 0 Probable transposase CCDC106 PF15794.5 RLN06848.1 - 4.1 7.1 14.0 0.07 12.8 2.2 2.9 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 106 bZIP_Maf PF03131.17 RLN06848.1 - 5.8 7.5 18.9 0.57 10.7 2.9 3.2 4 0 0 4 4 4 0 bZIP Maf transcription factor tRNA_bind PF01588.20 RLN06849.1 - 1.2e-26 92.7 0.0 1.9e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain DUF3391 PF11871.8 RLN06849.1 - 0.041 14.4 4.0 0.07 13.7 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) FGF-BP1 PF06473.12 RLN06849.1 - 0.37 10.6 5.2 0.49 10.2 5.2 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) RNA_pol_Rpc4 PF05132.14 RLN06849.1 - 0.66 10.4 6.6 1 9.8 6.6 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 CCDC53 PF10152.9 RLN06849.1 - 0.79 10.1 4.9 1.1 9.6 4.9 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Yip1 PF04893.17 RLN06850.1 - 6.2e-08 32.5 17.6 6.2e-08 32.5 17.6 1.6 1 1 1 2 2 2 1 Yip1 domain Cnd1 PF12717.7 RLN06851.1 - 3.1e-19 69.6 1.1 2.4e-18 66.7 0.1 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 RLN06851.1 - 0.00013 21.3 0.5 0.00035 19.9 0.5 1.7 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain Csd3_N PF18059.1 RLN06852.1 - 0.014 15.8 0.1 0.034 14.7 0.1 1.7 1 0 0 1 1 1 0 Csd3 N-terminal Ank_4 PF13637.6 RLN06862.1 - 6.7e-11 42.5 0.2 0.00046 20.7 0.0 4.6 3 3 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN06862.1 - 1.5e-07 31.6 0.5 2.9 8.3 0.0 6.0 6 1 0 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN06862.1 - 1e-06 29.2 0.0 0.56 10.8 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN06862.1 - 8.6e-05 22.7 0.0 69 4.5 0.0 5.8 6 0 0 6 6 6 0 Ankyrin repeat DUF249 PF03158.13 RLN06862.1 - 0.087 12.5 0.1 2.2 8.0 0.0 2.6 2 1 0 3 3 3 0 Multigene family 530 protein ABC_tran PF00005.27 RLN06863.1 - 1.9e-24 86.8 0.0 3.3e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN06863.1 - 4e-06 26.9 0.1 0.086 12.6 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 RLN06863.1 - 3e-05 23.6 2.4 4e-05 23.1 2.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_16 PF13191.6 RLN06863.1 - 6.8e-05 23.3 0.1 0.00015 22.2 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 RLN06863.1 - 0.00011 22.1 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN06863.1 - 0.0018 18.0 0.1 0.004 16.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN06863.1 - 0.007 16.0 0.0 0.12 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 RLN06863.1 - 0.01 15.3 0.1 0.84 9.0 0.0 2.5 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 RLN06863.1 - 0.02 14.6 0.1 0.04 13.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RLN06863.1 - 0.03 14.6 0.2 0.46 10.7 0.0 2.7 2 1 0 3 3 3 0 AAA domain AAA_23 PF13476.6 RLN06863.1 - 0.033 14.7 0.0 0.063 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 RLN06863.1 - 0.035 14.2 0.0 0.089 12.8 0.0 1.7 2 0 0 2 2 2 0 Dynamin family Rad17 PF03215.15 RLN06863.1 - 0.057 13.3 0.0 0.41 10.6 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain DUF4246 PF14033.6 RLN06884.1 - 2.9e-23 82.7 11.3 1.5e-22 80.4 0.0 2.7 1 1 2 3 3 3 2 Protein of unknown function (DUF4246) XAP5 PF04921.14 RLN06884.1 - 0.1 12.4 2.5 0.18 11.6 2.5 1.4 1 0 0 1 1 1 0 XAP5, circadian clock regulator GCIP PF13324.6 RLN06884.1 - 0.33 10.5 7.0 0.46 10.0 6.3 1.6 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 RLN06884.1 - 0.74 7.8 14.0 1.1 7.3 14.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 RLN06884.1 - 0.92 7.6 9.2 1.2 7.3 9.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RLN06884.1 - 2.6 7.4 11.3 3.5 7.0 11.3 1.2 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 RLN06884.1 - 2.7 6.4 7.4 4 5.9 7.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sporozoite_P67 PF05642.11 RLN06884.1 - 2.8 5.9 6.0 4 5.4 6.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.9 RLN06884.1 - 5.1 6.1 14.7 7.7 5.5 14.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4246 PF14033.6 RLN06885.1 - 4.8e-122 408.3 9.1 2.1e-103 346.9 0.0 4.2 3 2 0 3 3 3 3 Protein of unknown function (DUF4246) Acid_PPase PF12689.7 RLN06885.1 - 1.3e-47 161.8 0.0 2.6e-47 160.8 0.0 1.5 1 0 0 1 1 1 1 Acid Phosphatase 2OG-FeII_Oxy_5 PF13759.6 RLN06885.1 - 0.078 13.4 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase MtrB PF05440.12 RLN06885.1 - 0.25 11.8 5.3 21 5.6 0.1 4.0 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B Cys_rich_CWC PF14375.6 RLN06886.1 - 7.9 7.0 12.4 7.8 7.0 10.4 2.2 2 1 0 2 2 2 0 Cysteine-rich CWC tRNA_anti_2 PF13742.6 RLN06887.1 - 0.1 12.8 0.1 0.73 10.1 0.0 2.1 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain tRNA_anti-codon PF01336.25 RLN06887.1 - 0.14 12.2 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Acid_PPase PF12689.7 RLN06889.1 - 4.9e-52 176.2 0.0 6.6e-52 175.8 0.0 1.2 1 0 0 1 1 1 1 Acid Phosphatase FYVE_2 PF02318.16 RLN06890.1 - 0.23 11.7 10.7 0.56 10.4 9.7 2.2 2 1 0 2 2 2 0 FYVE-type zinc finger IBR PF01485.21 RLN06890.1 - 1.1 9.5 8.0 0.59 10.4 2.9 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Rubis-subs-bind PF09273.11 RLN06892.1 - 1.8e-11 44.8 0.1 3.6e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding HOOK PF05622.12 RLN06893.1 - 1.5e-12 46.6 16.3 1.5e-12 46.6 16.3 5.1 1 1 4 5 5 5 2 HOOK protein TPR_MLP1_2 PF07926.12 RLN06893.1 - 0.011 15.8 2.8 0.011 15.8 2.8 9.2 2 2 4 7 7 7 0 TPR/MLP1/MLP2-like protein DUF2771 PF10969.8 RLN06893.1 - 0.11 12.5 1.2 0.24 11.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2771) HALZ PF02183.18 RLN06893.1 - 1.4 9.2 0.0 1.4 9.2 0.0 7.3 6 1 0 6 6 6 0 Homeobox associated leucine zipper Shugoshin_N PF07558.11 RLN06893.1 - 3.3 7.7 9.2 4.7 7.2 0.1 4.9 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region Fib_alpha PF08702.10 RLN06893.1 - 6.8 6.9 53.2 0.24 11.6 0.1 7.2 4 1 1 6 6 6 0 Fibrinogen alpha/beta chain family CLASP_N PF12348.8 RLN06894.1 - 3.3e-17 62.8 7.0 3e-10 40.0 0.2 4.3 4 0 0 4 4 4 3 CLASP N terminal HEAT PF02985.22 RLN06894.1 - 1.2e-09 37.6 0.7 1.8 9.0 0.0 9.2 9 0 0 9 9 9 1 HEAT repeat Cnd1 PF12717.7 RLN06894.1 - 0.00014 21.9 5.9 0.0072 16.4 0.1 5.0 5 2 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 TAN PF11640.8 RLN06894.1 - 0.035 14.2 0.0 13 5.9 0.0 3.2 2 1 0 2 2 2 0 Telomere-length maintenance and DNA damage repair XPC-binding PF09280.11 RLN06894.1 - 0.061 13.1 0.0 1 9.2 0.0 2.8 2 0 0 2 2 2 0 XPC-binding domain RTP1_C1 PF10363.9 RLN06894.1 - 0.13 12.5 0.3 33 4.7 0.0 4.1 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Alpha_kinase PF02816.18 RLN06895.1 - 7.5e-51 172.9 0.2 1.5e-50 171.9 0.0 1.6 2 0 0 2 2 2 1 Alpha-kinase family LAP1C PF05609.12 RLN06895.1 - 2.1 7.3 11.1 0.24 10.4 6.4 1.7 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) SDA1 PF05285.12 RLN06895.1 - 5.4 6.3 17.0 0.33 10.3 9.0 2.3 2 0 0 2 2 2 0 SDA1 Cauli_VI PF01693.16 RLN06898.1 - 5.4e-31 106.6 3.0 3.2e-16 59.3 0.9 2.6 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 RLN06898.1 - 2.2e-05 24.7 0.0 4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 RNase H Ank_2 PF12796.7 RLN06901.1 - 7.5e-211 683.4 42.8 6.7e-20 71.5 0.1 14.7 1 1 12 15 15 15 15 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN06901.1 - 4.7e-170 530.4 35.0 4.3e-06 26.7 0.0 28.9 30 0 0 30 30 29 28 Ankyrin repeat Ank PF00023.30 RLN06901.1 - 1.2e-163 525.1 51.6 3.9e-06 27.1 0.1 29.0 29 0 0 29 29 29 28 Ankyrin repeat Ank_4 PF13637.6 RLN06901.1 - 3.6e-159 515.3 48.3 6.5e-10 39.4 0.2 21.2 8 4 13 22 22 22 22 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN06901.1 - 4e-134 434.9 71.4 2.1e-08 34.3 0.2 26.2 2 1 25 27 27 27 27 Ankyrin repeats (many copies) YlzJ PF14035.6 RLN06901.1 - 3.1e-06 27.3 0.0 32 4.8 0.0 9.5 13 1 0 13 13 12 0 YlzJ-like protein DUF749 PF05370.11 RLN06901.1 - 0.00016 21.7 0.0 30 4.8 0.0 5.4 6 0 0 6 6 5 0 Domain of unknown function (DUF749) YfmQ PF10787.9 RLN06901.1 - 0.00028 20.7 0.0 12 5.6 0.0 7.7 6 3 3 11 11 11 0 Uncharacterised protein from bacillus cereus group 3HCDH_RFF PF18321.1 RLN06901.1 - 0.0017 18.8 34.9 1 9.9 0.3 13.9 16 3 1 17 17 16 2 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain VWA_3_C PF18571.1 RLN06901.1 - 0.0023 17.7 27.3 17 5.3 0.0 14.7 18 1 1 19 19 19 0 von Willebrand factor type A C-terminal domain UCH_N PF16674.5 RLN06901.1 - 0.013 15.4 0.0 33 4.5 0.0 4.6 4 0 0 4 4 4 0 N-terminal of ubiquitin carboxyl-terminal hydrolase 37 Bac_rhamnosid_N PF08531.10 RLN06901.1 - 0.021 14.6 5.9 72 3.2 0.0 5.8 2 2 3 6 6 6 0 Alpha-L-rhamnosidase N-terminal domain IlvN PF07991.12 RLN06901.1 - 0.028 14.0 6.4 13 5.3 0.0 6.3 5 2 1 7 7 7 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Lpp-LpqN PF10738.9 RLN06901.1 - 0.075 12.5 0.0 0.32 10.4 0.0 2.1 1 0 0 1 1 1 0 Probable lipoprotein LpqN tRNA_NucTran2_2 PF13735.6 RLN06901.1 - 0.25 11.3 30.4 11 6.0 0.1 9.3 6 3 4 10 10 10 0 tRNA nucleotidyltransferase domain 2 putative Mic1 PF07035.12 RLN06901.1 - 1.2 8.9 17.4 1.3e+02 2.2 0.1 9.8 9 4 4 15 15 15 0 Colon cancer-associated protein Mic1-like SBP_bac_3 PF00497.20 RLN06901.1 - 6.8 6.0 14.3 15 4.9 0.2 6.4 3 3 2 6 6 6 0 Bacterial extracellular solute-binding proteins, family 3 Pirin PF02678.16 RLN06902.1 - 2.2e-26 91.9 0.0 4.6e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 RLN06902.1 - 3.4e-25 88.4 0.0 1.4e-24 86.5 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin_C_2 PF17954.1 RLN06902.1 - 0.044 14.0 0.0 0.21 11.8 0.0 2.1 2 0 0 2 2 2 0 Quercetinase C-terminal cupin domain Pirin PF02678.16 RLN06903.1 - 1.4e-29 102.3 0.0 2.9e-29 101.2 0.0 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 RLN06903.1 - 2.1e-28 98.7 0.0 6.6e-28 97.1 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin_C_2 PF17954.1 RLN06903.1 - 0.009 16.2 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain Cauli_VI PF01693.16 RLN06904.1 - 2.6e-29 101.2 2.2 7.2e-14 51.8 0.5 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 RLN06904.1 - 7.2e-20 71.6 0.0 1.1e-19 71.0 0.0 1.3 1 0 0 1 1 1 1 RNase H RNase_H PF00075.24 RLN06905.1 - 1.5e-19 70.6 0.0 2e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 RLN06905.1 - 8.9e-12 45.1 0.8 2.1e-11 43.9 0.8 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin PA PF02225.22 RLN10047.1 - 9.3e-14 51.2 0.6 7.3e-06 25.9 0.2 2.4 2 0 0 2 2 2 2 PA domain PRMT5_TIM PF17285.2 RLN10048.1 - 2.5e-67 226.8 0.0 4e-67 226.1 0.0 1.3 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 RLN10048.1 - 2.5e-57 193.5 0.1 4e-57 192.8 0.1 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 RLN10048.1 - 2.1e-54 184.1 0.0 3.3e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain LacAB_rpiB PF02502.18 RLN10048.1 - 0.066 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Ribose/Galactose Isomerase Methyltransf_31 PF13847.6 RLN10048.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF3584 PF12128.8 RLN10049.1 - 0.001 16.7 5.2 0.0012 16.5 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 RLN10049.1 - 0.009 16.2 3.9 0.52 10.5 0.1 2.2 2 0 0 2 2 2 2 Fibrinogen alpha/beta chain family DUF5586 PF17824.1 RLN10049.1 - 0.031 13.4 0.6 0.041 13.0 0.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5586) HIP1_clath_bdg PF16515.5 RLN10049.1 - 0.059 14.0 13.3 1.1 9.9 1.3 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HMMR_C PF15908.5 RLN10049.1 - 0.099 12.9 4.9 0.38 11.0 1.2 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal DUF1664 PF07889.12 RLN10049.1 - 0.19 11.8 6.2 0.072 13.1 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) KxDL PF10241.9 RLN10049.1 - 0.2 11.9 5.8 2.2 8.6 1.2 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein FUSC PF04632.12 RLN10049.1 - 0.26 9.8 12.3 0.3 9.6 12.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fez1 PF06818.15 RLN10049.1 - 0.27 11.7 10.1 0.4 11.1 10.1 1.3 1 1 0 1 1 1 0 Fez1 ATG16 PF08614.11 RLN10049.1 - 0.42 10.8 14.3 2.1 8.6 1.1 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 RLN10049.1 - 0.71 9.9 8.5 1.4 9.0 8.4 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus OmpH PF03938.14 RLN10049.1 - 1.1 9.6 10.3 13 6.1 10.4 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) HAUS6_N PF14661.6 RLN10049.1 - 1.2 8.7 7.3 0.5 9.9 4.3 1.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus FlxA PF14282.6 RLN10049.1 - 8.3 6.5 7.9 2.8 8.0 3.3 2.5 2 2 2 4 4 4 0 FlxA-like protein SARAF PF06682.12 RLN10050.1 - 0.00053 19.7 0.9 0.00053 19.7 0.9 1.6 2 0 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis DUF4131 PF13567.6 RLN10050.1 - 0.05 13.3 0.0 3 7.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Orthoreo_P10 PF07204.11 RLN10050.1 - 0.056 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DUF2076 PF09849.9 RLN10050.1 - 8.4 6.3 20.7 0.89 9.6 15.9 1.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Ubiq-Cytc-red_N PF09165.10 RLN10051.1 - 0.074 13.9 0.4 0.074 13.9 0.4 2.3 3 0 0 3 3 3 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal Vps35 PF03635.17 RLN10052.1 - 1.2e-226 754.7 0.1 1.4e-226 754.5 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 NTP_transf_3 PF12804.7 RLN10052.1 - 0.063 13.6 0.4 0.063 13.6 0.4 2.9 3 1 0 3 3 3 0 MobA-like NTP transferase domain Peptidase_M48_N PF16491.5 RLN10053.1 - 1.1e-63 214.5 1.1 1.7e-63 213.8 1.1 1.3 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices GBP PF02263.19 RLN10054.1 - 2.1e-24 86.2 0.0 7.5e-24 84.4 0.0 1.8 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 RLN10054.1 - 7.6e-06 25.5 13.1 7.6e-06 25.5 13.1 3.6 1 1 2 3 3 3 1 Guanylate-binding protein, C-terminal domain Erp_C PF06780.11 RLN10054.1 - 0.075 13.1 0.4 0.17 11.9 0.4 1.5 1 0 0 1 1 1 0 Erp protein C-terminus Sec23_helical PF04815.15 RLN10054.1 - 0.085 12.7 10.3 0.16 11.8 0.0 4.6 4 1 1 5 5 5 0 Sec23/Sec24 helical domain FR47 PF08445.10 RLN10067.1 - 0.00061 19.7 0.0 0.0018 18.2 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 RLN10067.1 - 0.0014 18.5 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 RLN10067.1 - 0.0022 18.0 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RLN10067.1 - 0.0032 17.7 0.0 0.021 15.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RLN10067.1 - 0.016 15.6 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ipi1_N PF12333.8 RLN10068.1 - 1.1e-11 45.2 0.0 1.1e-10 42.0 0.0 2.9 2 1 1 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.22 RLN10068.1 - 0.00063 19.8 3.5 0.9 10.0 0.2 4.8 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 RLN10068.1 - 0.016 15.6 6.6 0.057 13.8 0.8 3.7 3 0 0 3 3 3 0 HEAT repeats MMS19_N PF14500.6 RLN10068.1 - 0.033 13.8 0.3 0.16 11.6 0.0 2.3 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II ATP-gua_Ptrans PF00217.19 RLN10069.1 - 1.3e-75 253.6 0.0 1.7e-75 253.2 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 RLN10069.1 - 1.2e-28 99.3 0.0 2e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain MtN3_slv PF03083.16 RLN10070.1 - 4.8e-18 65.0 2.2 4e-17 62.0 0.3 2.3 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange Mtc PF03820.17 RLN10070.1 - 0.093 11.8 0.3 0.12 11.4 0.3 1.1 1 0 0 1 1 1 0 Tricarboxylate carrier DUF3445 PF11927.8 RLN10070.1 - 0.27 10.8 0.0 0.43 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) SpoIIE PF07228.12 RLN10073.1 - 6e-07 29.6 0.7 0.0082 16.1 0.0 2.8 1 1 1 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 RLN10073.1 - 0.0025 17.5 0.1 0.45 10.1 0.0 2.2 1 1 1 2 2 2 2 Protein phosphatase 2C Ribosomal_L20 PF00453.18 RLN10074.1 - 4.3e-40 136.1 1.8 5.1e-40 135.9 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 Cpn60_TCP1 PF00118.24 RLN10075.1 - 4.3e-138 461.0 1.1 5.1e-138 460.8 1.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Beta_helix_2 PF18835.1 RLN10075.1 - 0.084 12.6 0.1 3 7.7 0.0 2.4 2 0 0 2 2 2 0 Beta helix repeat of Inulin fructotransferase Glyco_hydro81C PF17652.1 RLN10076.1 - 1.2e-121 406.2 6.7 2e-121 405.5 6.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 RLN10076.1 - 3.1e-49 167.9 2.7 4.3e-49 167.4 2.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain SHOCT PF09851.9 RLN10084.1 - 0.15 11.8 0.1 0.42 10.4 0.1 1.7 1 0 0 1 1 1 0 Short C-terminal domain Methyltransf_25 PF13649.6 RLN10085.1 - 3.4e-19 69.3 0.0 7.9e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN10085.1 - 6.1e-16 58.7 0.0 8e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN10085.1 - 1.5e-15 57.7 0.0 2.5e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN10085.1 - 6.4e-15 55.6 0.0 1.5e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN10085.1 - 2.1e-14 53.6 0.0 2.9e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN10085.1 - 4e-11 42.8 0.0 5.8e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 RLN10085.1 - 8.5e-06 25.3 0.0 1.2e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 RLN10085.1 - 3.7e-05 23.1 0.0 0.00032 20.1 0.0 2.0 1 1 1 2 2 2 1 O-methyltransferase domain CheR PF01739.18 RLN10085.1 - 0.00094 18.7 0.0 0.01 15.3 0.0 2.0 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain CMAS PF02353.20 RLN10085.1 - 0.0022 17.4 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 RLN10085.1 - 0.0023 17.4 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_5 PF01795.19 RLN10085.1 - 0.014 15.0 0.0 0.033 13.7 0.0 1.6 1 1 0 1 1 1 0 MraW methylase family Rsm22 PF09243.10 RLN10085.1 - 0.028 13.7 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 RrnaAD PF00398.20 RLN10085.1 - 0.032 13.3 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 RLN10085.1 - 0.041 13.6 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase GidB PF02527.15 RLN10085.1 - 0.042 13.2 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G ADH_zinc_N PF00107.26 RLN10085.1 - 0.043 13.8 0.0 0.16 11.9 0.0 1.9 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_32 PF13679.6 RLN10085.1 - 0.067 13.2 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.17 RLN10085.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ABC_membrane PF00664.23 RLN10086.1 - 5.9e-27 95.0 18.2 7.4e-27 94.7 18.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN10086.1 - 2.5e-07 31.3 0.4 6.3e-07 30.0 0.4 1.7 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 RLN10086.1 - 0.0013 18.7 0.2 0.0035 17.4 0.2 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RLN10086.1 - 0.0051 16.7 1.6 0.0098 15.8 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 RLN10086.1 - 0.009 15.7 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 RLN10086.1 - 0.016 15.3 0.3 0.026 14.6 0.3 1.4 1 0 0 1 1 1 0 Dynamin family AAA_7 PF12775.7 RLN10086.1 - 0.043 13.3 0.1 0.097 12.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 RLN10086.1 - 0.061 12.6 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.13 RLN10086.1 - 0.11 11.6 0.1 0.22 10.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF4731 PF15875.5 RLN10086.1 - 0.14 12.3 0.2 1.9 8.8 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4731) DUF4212 PF13937.6 RLN10086.1 - 0.66 10.4 6.8 0.2 12.0 1.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) ABC_membrane PF00664.23 RLN10087.1 - 1.7e-64 218.2 35.5 4.3e-36 125.0 7.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN10087.1 - 1.6e-50 171.1 0.0 2.5e-28 99.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 RLN10087.1 - 2e-08 34.3 0.1 0.0068 16.5 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 RLN10087.1 - 1.4e-07 31.2 3.3 0.013 14.9 0.0 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RLN10087.1 - 3.3e-06 27.1 1.6 0.62 9.8 0.2 3.6 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN10087.1 - 1.3e-05 24.9 0.1 0.057 13.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN10087.1 - 2.8e-05 24.1 0.8 0.026 14.4 0.2 2.9 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 RLN10087.1 - 0.00029 20.9 0.0 0.036 14.1 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 RLN10087.1 - 0.0003 21.2 1.4 0.027 14.8 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 RLN10087.1 - 0.00034 21.2 0.9 0.97 9.9 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 RLN10087.1 - 0.0011 18.8 0.1 0.048 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RLN10087.1 - 0.0019 17.5 0.1 0.027 13.8 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 RLN10087.1 - 0.0026 17.3 0.1 0.2 11.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 RLN10087.1 - 0.0031 16.7 0.4 0.45 9.6 0.2 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) DUF87 PF01935.17 RLN10087.1 - 0.0048 17.0 2.6 0.038 14.1 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain IstB_IS21 PF01695.17 RLN10087.1 - 0.0049 16.6 0.6 9.4 5.9 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_22 PF13401.6 RLN10087.1 - 0.0066 16.7 0.1 3.6 7.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 RLN10087.1 - 0.016 15.4 0.0 0.31 11.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 RLN10087.1 - 0.028 14.0 0.3 1.9 8.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 RLN10087.1 - 0.029 14.6 0.1 8.2 6.7 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DEAD PF00270.29 RLN10087.1 - 0.037 13.8 0.2 0.24 11.1 0.0 2.4 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.6 RLN10087.1 - 0.039 14.5 0.0 20 5.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 RLN10087.1 - 0.12 12.0 0.6 3.9 7.0 0.2 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF3110 PF11360.8 RLN10087.1 - 0.17 12.1 0.1 0.44 10.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) AAA_15 PF13175.6 RLN10087.1 - 0.36 10.5 0.7 26 4.4 0.1 2.8 3 0 0 3 3 3 0 AAA ATPase domain PDT PF00800.18 RLN10088.1 - 5.3e-56 189.3 0.0 1.3e-55 188.1 0.0 1.7 1 0 0 1 1 1 1 Prephenate dehydratase PDH PF02153.17 RLN10088.1 - 1.8e-15 56.6 0.0 2.9e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 RLN10088.1 - 2.7e-06 27.9 0.0 8.5e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 RLN10088.1 - 0.052 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 RLN10088.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ion_trans PF00520.31 RLN10089.1 - 2.3e-43 148.2 26.2 1.2e-24 87.0 7.0 2.6 3 0 0 3 3 3 2 Ion transport protein Ion_trans_2 PF07885.16 RLN10089.1 - 1.2e-24 86.0 14.8 1e-14 54.2 1.7 3.4 4 0 0 4 4 4 2 Ion channel IRK PF01007.20 RLN10089.1 - 0.014 15.3 3.6 1.4 8.7 0.0 3.8 3 0 0 3 3 3 0 Inward rectifier potassium channel transmembrane domain TPH PF13868.6 RLN10090.1 - 2.7e-19 68.9 133.6 2.7e-19 68.9 133.6 2.1 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain tRNA_bind PF01588.20 RLN10132.1 - 3.7e-20 71.8 0.1 7e-17 61.3 0.0 2.3 2 0 0 2 2 2 2 Putative tRNA binding domain Ku_C PF03730.14 RLN10132.1 - 0.03 15.0 3.0 2.4 8.9 1.5 2.2 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm DUF3391 PF11871.8 RLN10132.1 - 0.036 14.6 1.0 0.048 14.2 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) FAP PF07174.11 RLN10132.1 - 0.04 13.4 4.0 0.05 13.0 4.0 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF3597 PF12200.8 RLN10132.1 - 1.5 9.4 4.8 2.3 8.7 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Yip1 PF04893.17 RLN10133.1 - 6.5e-07 29.2 17.0 1e-06 28.6 16.7 1.5 1 1 0 1 1 1 1 Yip1 domain DUF4715 PF15835.5 RLN10133.1 - 0.039 14.0 2.2 7.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4715) tRNA_lig_kinase PF08303.11 RLN10133.1 - 0.082 13.0 0.4 0.15 12.1 0.4 1.4 1 0 0 1 1 1 0 tRNA ligase kinase domain MRP-S31 PF15433.6 RLN10133.1 - 3 7.4 5.5 4.7 6.8 5.5 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Ank_2 PF12796.7 RLN10138.1 - 3.4e-39 133.3 7.7 3.7e-21 75.5 0.3 2.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN10138.1 - 1.1e-29 102.4 11.8 3.1e-08 34.0 0.1 4.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN10138.1 - 5.1e-22 77.6 5.7 4.2e-06 26.9 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN10138.1 - 1.2e-19 69.8 10.3 1.9e-07 31.2 0.1 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 RLN10138.1 - 6.9e-19 66.0 3.7 0.0048 17.3 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat MtrG PF04210.13 RLN10139.1 - 0.086 12.7 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF1515 PF07439.11 RLN10139.1 - 0.13 12.3 1.3 0.22 11.6 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) DAGAT PF03982.13 RLN10140.1 - 1.3e-34 119.5 0.0 2.4e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Thump_like PF18096.1 RLN10142.1 - 0.044 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 THUMP domain-like BAT PF15915.5 RLN10142.1 - 0.18 11.7 3.5 0.22 11.4 0.9 2.3 2 0 0 2 2 2 0 GAF and HTH_10 associated domain Noggin PF05806.12 RLN10142.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Noggin Gaa1 PF04114.14 RLN10143.1 - 1.2e-41 143.4 0.0 1.4e-41 143.1 0.0 1.0 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Pkinase PF00069.25 RLN10146.1 - 1.5e-34 119.5 0.0 2.2e-33 115.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN10146.1 - 5.4e-15 55.4 0.0 5.9e-14 52.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_1 PF00232.18 RLN10154.1 - 5.9e-115 384.3 0.0 8.2e-115 383.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 RLN10154.1 - 0.00044 19.8 0.0 0.0011 18.5 0.0 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) PT-VENN PF04829.13 RLN10154.1 - 0.076 13.1 1.6 0.21 11.7 1.6 1.8 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Glyco_hydro_1 PF00232.18 RLN10155.1 - 1.6e-128 429.0 0.1 1.9e-128 428.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Lipase_GDSL_2 PF13472.6 RLN10155.1 - 0.0058 17.0 0.0 0.017 15.6 0.0 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Cellulase PF00150.18 RLN10155.1 - 0.039 13.4 0.1 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Proteasome PF00227.26 RLN10156.1 - 3e-13 49.7 0.0 3.5e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF3177 PF11375.8 RLN10156.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) DUF1771 PF08590.10 RLN10157.1 - 4.5e-11 43.0 9.4 4.5e-11 43.0 9.4 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.21 RLN10157.1 - 9.6e-11 41.9 0.3 8.8e-10 38.8 0.1 2.5 2 0 0 2 2 2 1 Smr domain PRIMA1 PF16101.5 RLN10157.1 - 4.6 7.3 4.6 2.4 8.2 1.4 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Glyco_hydro_1 PF00232.18 RLN10158.1 - 0 1199.0 2.3 2.1e-123 412.1 0.1 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 1 Cellulase PF00150.18 RLN10158.1 - 7.2e-05 22.4 2.7 1.2 8.6 0.0 4.2 4 0 0 4 4 4 3 Cellulase (glycosyl hydrolase family 5) Lipase_GDSL_2 PF13472.6 RLN10158.1 - 0.005 17.3 0.0 2.8 8.3 0.0 3.6 3 0 0 3 3 3 1 GDSL-like Lipase/Acylhydrolase family NepR PF18557.1 RLN10158.1 - 3.2 7.5 5.5 1e+02 2.7 0.1 3.6 3 0 0 3 3 3 0 Anti-sigma factor NepR Piwi PF02171.17 RLN10159.1 - 1.5e-91 306.8 0.0 2.3e-91 306.2 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 RLN10159.1 - 1.8e-16 60.2 0.0 3.6e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 RLN10159.1 - 1.4e-15 58.1 0.0 4e-15 56.7 0.0 1.9 1 1 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 RLN10159.1 - 2.7e-15 55.8 0.0 5.1e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 RLN10159.1 - 6.1e-13 48.9 0.0 1.8e-12 47.4 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 RLN10159.1 - 8.1e-12 45.2 0.2 6.3e-11 42.4 0.0 2.5 3 0 0 3 3 3 1 Mid domain of argonaute Glyco_hydro_1 PF00232.18 RLN10160.1 - 5.4e-255 845.9 2.5 1.1e-127 426.3 0.1 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 1 DUF2561 PF10812.8 RLN10160.1 - 0.00045 20.3 3.2 0.55 10.2 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2561) DUF3218 PF11508.8 RLN10160.1 - 0.0032 17.0 0.0 2.4 7.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3218) MAP17 PF15807.5 RLN10160.1 - 0.055 13.7 5.1 0.23 11.7 0.4 2.4 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 baeRF_family8 PF18851.1 RLN10160.1 - 0.15 12.2 0.0 28 4.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 8 Clc-like PF07062.12 RLN10160.1 - 0.19 11.2 1.1 14 5.0 0.1 2.2 2 0 0 2 2 2 0 Clc-like DUF4715 PF15835.5 RLN10160.1 - 0.21 11.7 0.0 28 4.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4715) Ferredoxin_N PF16947.5 RLN10160.1 - 0.33 11.1 2.0 28 4.9 0.1 2.7 2 0 0 2 2 2 0 N-terminal region of 4Fe-4S ferredoxin iron-sulfur binding DAP10 PF07213.11 RLN10160.1 - 0.7 9.9 2.7 25 4.9 0.3 2.5 2 0 0 2 2 2 0 DAP10 membrane protein TrbC PF04956.13 RLN10160.1 - 1.2 9.4 7.4 8.5 6.7 0.3 3.2 3 0 0 3 3 3 0 TrbC/VIRB2 family PPAK PF02818.15 RLN10160.1 - 6.6 7.0 10.9 16 5.8 1.9 2.4 2 0 0 2 2 2 0 PPAK motif Ank_2 PF12796.7 RLN10161.1 - 1e-61 205.5 16.7 1.4e-13 51.3 0.5 13.6 10 3 5 15 15 15 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN10161.1 - 2.1e-50 168.5 26.4 1e-05 25.9 0.1 17.6 15 5 5 20 20 20 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN10161.1 - 5.1e-44 147.8 33.7 7.1e-06 26.2 0.6 15.4 11 3 5 16 16 16 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN10161.1 - 1.4e-34 114.2 21.2 0.093 13.3 0.0 18.8 20 0 0 20 20 20 8 Ankyrin repeat PARP PF00644.20 RLN10161.1 - 3.1e-32 111.7 0.0 8e-32 110.4 0.0 1.6 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Ank PF00023.30 RLN10161.1 - 1.3e-30 104.4 37.1 0.001 19.4 0.2 18.2 21 0 0 21 21 21 9 Ankyrin repeat WGR PF05406.15 RLN10161.1 - 3e-20 72.1 0.0 6.6e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 WGR domain PARP_reg PF02877.14 RLN10161.1 - 7.4e-08 32.6 0.0 1.4e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain Nop14 PF04147.12 RLN10161.1 - 1.8 6.7 13.5 2.9 6.0 13.5 1.2 1 0 0 1 1 1 0 Nop14-like family PX PF00787.24 RLN10169.1 - 0.14 12.2 0.2 17 5.5 0.1 2.5 2 1 0 2 2 2 0 PX domain PX PF00787.24 RLN10170.1 - 0.021 14.8 0.1 1.9 8.5 0.1 2.2 2 0 0 2 2 2 0 PX domain zf-C2H2_4 PF13894.6 RLN10171.1 - 9.4e-05 22.9 1.7 0.43 11.6 0.1 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 RLN10171.1 - 0.00022 21.5 2.2 0.25 11.9 0.2 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type Rad50_zn_hook PF04423.14 RLN10171.1 - 0.007 16.2 1.7 1.5 8.7 0.1 2.2 1 1 1 2 2 2 2 Rad50 zinc hook motif zf-C2H2_jaz PF12171.8 RLN10171.1 - 0.017 15.4 0.7 0.017 15.4 0.7 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 RLN10171.1 - 0.025 14.8 1.3 0.35 11.2 0.1 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF1859 PF08948.10 RLN10171.1 - 0.03 14.3 0.1 0.052 13.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1859) LMWPc PF01451.21 RLN10172.1 - 1e-25 90.8 0.2 2.8e-24 86.1 0.2 2.1 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase KH_8 PF17903.1 RLN10173.1 - 6.4e-32 109.5 0.0 1.5e-31 108.3 0.0 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain Herpes_UL52 PF03121.15 RLN10174.1 - 3.5e-11 42.9 0.3 6.8e-11 41.9 0.3 1.5 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase PLAC8 PF04749.17 RLN10176.1 - 0.0088 17.0 0.7 0.037 15.0 0.7 1.9 1 1 0 1 1 1 1 PLAC8 family Wzy_C PF04932.15 RLN10176.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.4 2 1 1 3 3 3 0 O-Antigen ligase Myb_DNA-bind_3 PF12776.7 RLN10177.1 - 2.3e-11 44.5 0.1 1.5e-06 29.1 0.0 3.3 2 1 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 RLN10177.1 - 1.8e-06 28.2 0.0 0.01 16.2 0.0 2.7 2 1 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 RLN10177.1 - 0.0026 17.8 0.2 0.019 15.1 0.1 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 RLN10177.1 - 0.0044 17.3 0.5 0.48 10.8 0.1 2.9 2 1 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like TetR_C_6 PF13977.6 RLN10177.1 - 0.021 15.0 0.1 0.62 10.3 0.2 2.4 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal DUF4644 PF15486.6 RLN10177.1 - 0.048 13.4 0.3 0.16 11.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4644) FYVE PF01363.21 RLN10179.1 - 7.7e-15 54.8 17.3 1.4e-14 53.9 17.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger Pkinase_Tyr PF07714.17 RLN10180.1 - 1.8e-40 138.9 0.0 3.4e-40 138.0 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RLN10180.1 - 3e-36 125.1 0.0 4.8e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RLN10180.1 - 0.032 13.6 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Orn_Arg_deC_N PF02784.16 RLN10181.1 - 7.2e-72 241.7 0.0 8.9e-72 241.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 RLN10181.1 - 3e-13 49.8 0.0 3.2e-13 49.7 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Mlo PF03094.15 RLN10182.1 - 3e-06 25.9 11.1 0.00042 18.8 0.4 2.6 2 1 0 2 2 2 2 Mlo family Spc110_C PF18520.1 RLN10182.1 - 6.1e-05 22.5 0.9 0.00013 21.5 0.9 1.5 1 0 0 1 1 1 1 Spindle pole body component 110 C-terminal domain PACT_coil_coil PF10495.9 RLN10182.1 - 0.0035 17.9 0.6 0.0035 17.9 0.6 2.2 2 0 0 2 2 2 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein PCIF1_WW PF12237.8 RLN10182.1 - 0.15 11.7 0.0 0.93 9.1 0.0 2.1 2 0 0 2 2 2 0 Phosphorylated CTD interacting factor 1 WW domain DDE_Tnp_4 PF13359.6 RLN10216.1 - 4e-15 55.8 0.0 4.6e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease PDEase_I PF00233.19 RLN10217.1 - 1.6e-13 50.9 0.2 4e-13 49.7 0.1 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I PF00233.19 RLN10218.1 - 1.3e-24 87.2 0.0 1.6e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase FANCI_S2 PF14676.6 RLN10220.1 - 2.2e-37 128.9 0.3 4.9e-37 127.8 0.3 1.6 1 0 0 1 1 1 1 FANCI solenoid 2 FANCI_HD2 PF14680.6 RLN10220.1 - 9.8e-30 103.6 0.2 2.5e-29 102.2 0.2 1.6 1 0 0 1 1 1 1 FANCI helical domain 2 FANCI_S4 PF14678.6 RLN10220.1 - 5e-19 68.4 0.1 1.4e-18 67.0 0.1 1.7 1 0 0 1 1 1 1 FANCI solenoid 4 FANCI_S1 PF14675.6 RLN10220.1 - 9.1e-18 64.6 0.0 2.3e-16 60.0 0.0 2.8 2 1 0 2 2 2 1 FANCI solenoid 1 SlyX PF04102.12 RLN10224.1 - 0.0015 19.1 0.4 0.0035 17.9 0.0 1.8 2 0 0 2 2 2 1 SlyX MerR-DNA-bind PF09278.11 RLN10224.1 - 0.03 14.8 1.2 0.03 14.8 1.2 1.8 2 0 0 2 2 2 0 MerR, DNA binding Flu_PB1 PF00602.17 RLN10224.1 - 0.17 10.0 0.0 0.2 9.7 0.0 1.0 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 Aa_trans PF01490.18 RLN10229.1 - 8.3e-11 41.2 2.2 9.6e-11 41.0 2.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 RLN10229.1 - 0.0042 16.2 1.7 0.0045 16.1 1.7 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family GLTP PF08718.11 RLN10230.1 - 5.8e-18 65.6 0.0 1.1e-17 64.7 0.0 1.3 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) zf-AD PF07776.15 RLN10230.1 - 0.0082 16.4 0.1 0.022 15.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-finger associated domain (zf-AD) NifU_N PF01592.16 RLN10231.1 - 4.4e-55 185.3 0.2 5.3e-55 185.0 0.2 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Podoplanin PF05808.11 RLN10232.1 - 0.00013 22.1 2.6 0.00013 22.1 2.6 2.3 1 1 1 2 2 2 1 Podoplanin PTPLA PF04387.14 RLN10233.1 - 3.6e-48 163.4 10.6 4.3e-46 156.6 10.6 2.2 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA P5CR_dimer PF14748.6 RLN10233.1 - 0.14 12.5 0.4 0.22 11.8 0.4 1.2 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation FAIM1 PF06905.13 RLN10241.1 - 7.7e-05 22.5 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) zf-RanBP PF00641.18 RLN10241.1 - 0.013 14.8 0.9 0.04 13.2 0.9 1.8 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others CBM_35 PF16990.5 RLN10241.1 - 0.15 12.3 0.1 0.27 11.5 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate binding module (family 35) Exo_endo_phos PF03372.23 RLN10242.1 - 1.5e-07 31.2 0.0 2.3e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sina PF03145.16 RLN10242.1 - 0.09 12.7 0.9 0.17 11.8 0.9 1.4 1 0 0 1 1 1 0 Seven in absentia protein family Exo_endo_phos_2 PF14529.6 RLN10242.1 - 0.16 11.8 0.1 0.59 10.0 0.0 2.1 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase Gln-synt_C PF00120.24 RLN10243.1 - 0.0001 21.5 0.0 0.00011 21.4 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Utp14 PF04615.13 RLN10244.1 - 0.094 11.3 36.5 0.11 11.1 36.5 1.0 1 0 0 1 1 1 0 Utp14 protein COX17 PF05051.13 RLN10245.1 - 7.5e-20 71.0 5.6 8.9e-20 70.8 5.6 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Hep_core_N PF08290.11 RLN10245.1 - 0.26 11.3 7.1 0.15 12.0 3.9 2.0 2 0 0 2 2 2 0 Hepatitis core protein, putative zinc finger WD40 PF00400.32 RLN10246.1 - 3.5e-09 37.1 1.0 0.037 14.9 0.0 4.6 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN10246.1 - 0.0001 22.5 0.0 4.3 7.7 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain GH-E PF14410.6 RLN10246.1 - 0.2 12.1 0.0 0.51 10.8 0.0 1.6 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues EFG_C PF00679.24 RLN10247.1 - 4.5e-11 42.6 0.0 9.8e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 RLN10247.1 - 0.00043 20.1 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU PF00009.27 RLN10247.1 - 0.069 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain EFG_II PF14492.6 RLN10247.1 - 0.15 12.2 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 Elongation Factor G, domain II Peptidase_C48 PF02902.19 RLN10248.1 - 5.8e-33 114.6 1.3 1.3e-32 113.4 1.3 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain NCBP3 PF10309.9 RLN10248.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 Pkinase PF00069.25 RLN10249.1 - 1e-59 202.1 0.0 1.2e-59 201.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN10249.1 - 3.7e-30 105.1 0.0 5.4e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN10249.1 - 0.00011 21.7 0.2 0.00024 20.5 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN10249.1 - 0.00012 22.1 4.8 0.00045 20.2 1.3 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN10249.1 - 0.0014 17.5 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN10249.1 - 0.0055 16.1 0.4 0.041 13.2 0.0 2.2 3 0 0 3 3 3 1 Kinase-like Ank_2 PF12796.7 RLN10250.1 - 7e-07 29.7 0.0 0.0048 17.5 0.0 2.1 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN10250.1 - 2.1e-06 28.1 0.0 0.0064 17.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN10250.1 - 7.8e-05 22.9 0.2 0.0047 17.2 0.0 2.9 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN10250.1 - 0.00028 21.1 0.0 0.22 12.2 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 RLN10250.1 - 0.014 15.8 0.2 8 7.1 0.0 3.1 1 1 2 3 3 3 0 Ankyrin repeat DUF4841 PF16129.5 RLN10251.1 - 0.043 14.1 0.5 8.9 6.6 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4841) Crystall_3 PF08964.10 RLN10251.1 - 0.057 13.6 0.1 9.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Beta/Gamma crystallin Mitofilin PF09731.9 RLN10252.1 - 0.16 10.8 21.2 0.17 10.7 21.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MA3 PF02847.17 RLN10315.1 - 6.2e-25 87.4 1.3 2e-24 85.7 1.3 1.9 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 RLN10315.1 - 7e-17 61.8 0.3 3.8e-16 59.4 0.0 2.3 3 0 0 3 3 3 1 MIF4G domain DUF5523 PF17661.1 RLN10315.1 - 0.0091 15.7 6.4 0.0091 15.7 6.4 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5523) FAM176 PF14851.6 RLN10315.1 - 0.023 14.3 7.5 1.8 8.2 0.1 2.5 2 0 0 2 2 2 0 FAM176 family Na_trans_assoc PF06512.13 RLN10315.1 - 0.54 10.5 10.9 0.47 10.7 2.1 2.4 2 0 0 2 2 2 0 Sodium ion transport-associated AF-4 PF05110.13 RLN10315.1 - 3.6 5.5 41.5 0.013 13.6 0.7 2.3 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Ank_2 PF12796.7 RLN10350.1 - 3.1e-41 139.8 10.3 5.1e-12 46.2 0.2 4.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN10350.1 - 4.2e-33 113.3 0.8 3.9e-08 33.7 0.0 5.8 1 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 RLN10350.1 - 3.7e-27 93.5 8.9 0.00016 21.9 0.0 7.9 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 RLN10350.1 - 9.8e-26 89.5 3.8 1.4e-05 25.3 0.1 6.7 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN10350.1 - 8.1e-21 71.9 0.0 0.12 13.0 0.0 7.8 7 0 0 7 7 7 6 Ankyrin repeat FliS_cochap PF16522.5 RLN10350.1 - 0.057 13.4 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 Flagellar FLiS export co-chaperone, HP1076 PK_C PF02887.16 RLN10350.1 - 0.41 10.9 4.0 1.2e+02 3.0 0.0 4.8 5 0 0 5 5 5 0 Pyruvate kinase, alpha/beta domain RPW8 PF05659.11 RLN10350.1 - 7.5 6.2 12.3 19 5.0 0.1 5.3 4 1 1 5 5 5 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Peptidase_C1 PF00112.23 RLN10351.1 - 1.7e-52 178.7 13.7 2.6e-52 178.1 13.7 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RLN10351.1 - 0.00032 19.6 0.7 0.13 11.0 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family ABC2_membrane PF01061.24 RLN10352.1 - 1.8e-29 102.7 32.4 2.7e-29 102.1 32.4 1.3 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN10352.1 - 0.00014 21.7 3.2 0.00031 20.6 0.2 2.9 3 0 0 3 3 3 1 CDR ABC transporter ABC2_membrane PF01061.24 RLN10353.1 - 6.1e-70 234.9 65.7 3.6e-38 131.1 26.2 2.6 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN10353.1 - 4.4e-36 124.4 0.1 5.8e-17 62.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 RLN10353.1 - 6.2e-08 32.4 3.6 3.2e-06 26.9 0.1 3.5 3 0 0 3 3 2 1 CDR ABC transporter Zeta_toxin PF06414.12 RLN10353.1 - 6.5e-08 32.1 0.4 2.1e-05 23.9 0.0 2.8 2 1 1 3 3 3 1 Zeta toxin AAA_21 PF13304.6 RLN10353.1 - 2.2e-07 31.0 0.0 0.14 12.0 0.0 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN10353.1 - 1.9e-06 28.4 0.1 0.0052 17.2 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 RLN10353.1 - 1.4e-05 25.5 0.1 0.067 13.6 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 RLN10353.1 - 1.9e-05 24.3 0.1 0.072 12.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 RLN10353.1 - 2.3e-05 24.4 1.8 0.032 14.1 0.4 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 RLN10353.1 - 2.4e-05 24.6 0.1 0.056 13.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 RLN10353.1 - 3.5e-05 23.5 4.9 0.027 14.2 0.6 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain cobW PF02492.19 RLN10353.1 - 0.00023 20.8 0.6 0.43 10.1 0.0 2.8 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 RLN10353.1 - 0.00029 21.4 0.8 0.21 12.1 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 RLN10353.1 - 0.00076 19.3 1.0 1 9.1 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 RLN10353.1 - 0.00092 19.4 0.1 0.67 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RLN10353.1 - 0.0024 18.4 0.0 1.7 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 RLN10353.1 - 0.0027 17.9 0.2 0.41 10.9 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase PDR_assoc PF08370.11 RLN10353.1 - 0.0041 16.8 0.1 0.0041 16.8 0.1 3.3 3 0 0 3 3 2 1 Plant PDR ABC transporter associated AAA_5 PF07728.14 RLN10353.1 - 0.0055 16.7 0.1 0.15 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 RLN10353.1 - 0.0083 16.1 0.5 6.7 6.7 0.2 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 RLN10353.1 - 0.011 15.7 3.6 0.83 9.5 0.0 2.8 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 RLN10353.1 - 0.012 15.4 0.4 2.2 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 RLN10353.1 - 0.017 14.6 2.8 1.2 8.5 0.2 3.5 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.9 RLN10353.1 - 0.025 14.3 1.7 6.6 6.5 0.4 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 RLN10353.1 - 0.029 14.4 1.8 3.7 7.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase RuvB_N PF05496.12 RLN10353.1 - 0.067 12.9 0.4 4 7.1 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 RLN10353.1 - 0.11 12.9 0.5 12 6.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.6 RLN10353.1 - 0.11 12.8 0.0 6.9 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RLN10353.1 - 0.15 12.3 1.2 28 4.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 RLN10353.1 - 0.16 11.9 0.6 2 8.3 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Gtr1_RagA PF04670.12 RLN10353.1 - 0.27 10.5 0.7 15 4.8 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Mg_chelatase PF01078.21 RLN10353.1 - 0.37 10.1 0.8 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF87 PF01935.17 RLN10353.1 - 4.2 7.4 5.7 26 4.8 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain ABC2_membrane_3 PF12698.7 RLN10353.1 - 6.4 5.8 50.4 0.22 10.6 11.8 3.7 3 1 0 4 4 4 0 ABC-2 family transporter protein Aldo_ket_red PF00248.21 RLN10354.1 - 1.7e-69 234.2 0.0 2e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DAO PF01266.24 RLN10360.1 - 2.9e-37 129.1 0.4 1.5e-36 126.7 0.4 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RLN10360.1 - 0.00019 20.8 0.0 0.00052 19.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RLN10360.1 - 0.011 14.5 0.0 0.026 13.3 0.0 1.6 1 0 0 1 1 1 0 HI0933-like protein AMMECR1 PF01871.17 RLN10363.1 - 6.4e-28 97.5 0.0 6.9e-23 81.1 0.0 2.0 2 0 0 2 2 2 2 AMMECR1 Mannosyl_trans3 PF11051.8 RLN10381.1 - 1.7e-26 93.2 0.0 1.4e-25 90.2 0.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.8 RLN10382.1 - 3.5e-33 115.2 0.0 7.2e-32 110.8 0.0 2.1 1 1 0 1 1 1 1 Mannosyltransferase putative CPSF_A PF03178.15 RLN10385.1 - 1.1e-59 202.4 0.0 1.7e-59 201.7 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 RLN10385.1 - 6.4e-29 100.9 0.0 1e-28 100.2 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Methyltransf_24 PF13578.6 RLN10386.1 - 8.6e-10 39.6 0.1 1.7e-09 38.6 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 RLN10386.1 - 0.0015 17.8 0.0 0.0034 16.6 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.6 RLN10386.1 - 0.036 13.9 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RRN3 PF05327.11 RLN10388.1 - 0.0011 17.7 1.7 0.0012 17.5 1.7 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 YL1 PF05764.13 RLN10388.1 - 0.0093 16.1 3.7 0.013 15.7 3.7 1.2 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 RLN10388.1 - 0.019 13.3 1.3 0.023 13.0 1.3 1.1 1 0 0 1 1 1 0 CDC45-like protein XAP5 PF04921.14 RLN10388.1 - 0.02 14.8 4.7 0.028 14.3 4.7 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Nop14 PF04147.12 RLN10388.1 - 0.12 10.6 6.5 0.15 10.3 6.5 1.1 1 0 0 1 1 1 0 Nop14-like family Rhabdo_ncap PF00945.18 RLN10388.1 - 0.22 10.3 2.1 0.32 9.8 2.1 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein PDDEXK_6 PF04720.12 RLN10388.1 - 0.31 11.0 3.1 0.45 10.4 3.1 1.2 1 0 0 1 1 1 0 PDDEXK-like family of unknown function PPP4R2 PF09184.11 RLN10388.1 - 0.94 9.0 7.7 1.3 8.5 7.7 1.1 1 0 0 1 1 1 0 PPP4R2 adh_short PF00106.25 RLN10389.1 - 6.9e-38 130.1 2.0 3.9e-20 72.1 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN10389.1 - 8.2e-21 74.6 0.5 3.7e-11 43.1 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN10389.1 - 1.5e-05 25.0 0.3 0.00014 21.8 0.1 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 RLN10389.1 - 0.016 14.6 0.1 0.73 9.2 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 RLN10389.1 - 0.045 13.7 0.1 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 RLN10389.1 - 0.045 13.1 0.8 1 8.7 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 RLN10389.1 - 0.077 12.4 0.4 0.2 11.0 0.1 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase ORC6 PF05460.13 RLN10390.1 - 1.4 8.2 7.6 2 7.6 7.6 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Aminotran_1_2 PF00155.21 RLN10404.1 - 2.1e-50 171.9 0.0 2.6e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 RLN10404.1 - 8.3e-06 25.3 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 RLN10404.1 - 3.6e-05 22.5 0.0 5.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 RLN10404.1 - 6.6e-05 22.4 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 RLN10404.1 - 0.00032 19.6 0.2 0.00077 18.3 0.2 1.7 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 RLN10404.1 - 0.0074 15.3 0.1 0.012 14.6 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V WD40 PF00400.32 RLN10405.1 - 3.6e-10 40.3 0.2 0.0074 17.1 0.1 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN10405.1 - 2.2e-08 34.3 0.0 0.0052 17.1 0.0 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 RLN10405.1 - 0.055 13.0 0.0 0.065 12.8 0.0 1.1 1 0 0 1 1 1 0 PQQ-like domain DPPIV_N PF00930.21 RLN10405.1 - 0.061 12.1 0.0 1.6 7.4 0.0 2.0 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.12 RLN10405.1 - 0.076 13.0 0.0 0.49 10.4 0.0 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Methyltransf_11 PF08241.12 RLN10406.1 - 1.1e-12 48.4 0.0 4.3e-12 46.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN10406.1 - 5.8e-10 39.2 0.0 1.3e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN10406.1 - 1.6e-09 38.3 0.0 5.2e-09 36.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN10406.1 - 4e-05 23.5 0.1 0.00016 21.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Glyco_hydr_30_2 PF14587.6 RLN10407.1 - 2.6e-15 56.9 2.1 3.7e-15 56.4 2.1 1.2 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 DUF2407_C PF13373.6 RLN10408.1 - 9e-25 87.5 0.1 1.3e-24 87.0 0.1 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.23 RLN10408.1 - 1.6e-13 50.2 0.0 2.5e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 RLN10408.1 - 4e-05 24.1 0.1 7.2e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 RLN10408.1 - 0.00047 20.2 0.2 0.044 13.8 0.1 2.3 1 1 1 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 RLN10408.1 - 0.002 18.2 0.0 0.0039 17.3 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 RLN10408.1 - 0.0021 17.8 0.0 0.0039 17.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CbtA PF09490.10 RLN10408.1 - 0.083 12.6 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) DUF4203 PF13886.6 RLN10408.1 - 0.098 12.3 1.4 0.14 11.8 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) Kinesin PF00225.23 RLN10409.1 - 1.2e-85 287.4 5.0 1.6e-70 237.7 0.2 2.9 2 1 1 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 RLN10409.1 - 1.6e-08 34.6 0.0 7.3e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding DEAD PF00270.29 RLN10409.1 - 0.075 12.8 0.2 5.6 6.7 0.0 2.9 3 0 0 3 3 3 0 DEAD/DEAH box helicase YabA PF06156.13 RLN10409.1 - 0.091 13.4 19.0 0.12 13.1 0.4 4.0 3 1 0 3 3 3 0 Initiation control protein YabA Kinesin PF00225.23 RLN10410.1 - 5.2e-94 314.9 0.1 2.9e-93 312.4 0.1 1.9 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN10410.1 - 1.2e-12 48.1 0.0 2.6e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 RLN10410.1 - 0.092 13.1 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain PACT_coil_coil PF10495.9 RLN10427.1 - 0.035 14.7 0.6 0.035 14.7 0.6 4.7 4 1 0 4 4 4 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein NPBW PF15180.6 RLN10427.1 - 0.64 9.9 8.8 1.4 8.8 0.4 4.4 3 0 0 3 3 3 0 Neuropeptides B and W Myb_DNA-binding PF00249.31 RLN10428.1 - 1.3e-09 38.1 0.0 2.2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 RLN10429.1 - 1.1e-09 38.3 0.1 2.1e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN10429.1 - 0.0055 16.9 0.1 0.013 15.8 0.1 1.6 1 1 0 1 1 1 1 Myb-like DNA-binding domain IQ PF00612.27 RLN10432.1 - 6e-14 50.5 48.4 0.0035 17.0 0.1 9.0 8 0 0 8 8 8 7 IQ calmodulin-binding motif LRR_6 PF13516.6 RLN10432.1 - 6.1e-13 47.7 8.9 0.055 13.5 0.0 7.4 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 RLN10432.1 - 0.00059 20.2 2.2 45 4.7 0.0 5.2 2 1 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN10432.1 - 9.9 7.2 7.3 75 4.5 0.0 5.2 6 1 0 6 6 6 0 Leucine Rich Repeat Spt5-NGN PF03439.13 RLN10433.1 - 1.1e-19 70.0 0.0 3.9e-19 68.3 0.0 2.0 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 RLN10433.1 - 1.1e-16 60.1 43.0 0.00015 21.6 2.4 8.8 9 0 0 9 9 9 7 KOW motif Spt5_N PF11942.8 RLN10433.1 - 3.9e-11 43.8 19.2 3.9e-11 43.8 19.2 2.8 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal DUF3912 PF13051.6 RLN10433.1 - 0.0098 16.1 4.2 0.19 12.0 0.3 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3912) Pox_Ag35 PF03286.14 RLN10433.1 - 3.2 7.5 22.6 7.1 6.4 22.6 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2457 PF10446.9 RLN10434.1 - 0.031 13.4 1.6 0.035 13.3 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PolyA_pol_RNAbd PF12627.7 RLN10434.1 - 0.04 13.7 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A DUF389 PF04087.14 RLN10435.1 - 3.7e-22 78.9 3.5 6e-22 78.2 3.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF389) ALMT PF11744.8 RLN10435.1 - 0.029 13.2 1.6 0.051 12.4 1.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter zf-CCCH PF00642.24 RLN10436.1 - 4e-11 42.5 22.1 6e-07 29.2 2.3 3.7 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ANAPC4_WD40 PF12894.7 RLN10436.1 - 0.00018 21.8 0.3 15 5.9 0.0 4.6 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Torus PF16131.5 RLN10436.1 - 0.00018 22.2 5.6 0.53 11.0 0.2 3.4 3 0 0 3 3 3 2 Torus domain RRM_1 PF00076.22 RLN10436.1 - 0.0004 20.2 0.0 0.00083 19.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 RLN10436.1 - 0.00084 19.3 15.4 0.023 14.7 2.3 2.8 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 RLN10436.1 - 0.043 14.0 1.1 8.1 6.7 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger containing family Hira PF07569.11 RLN10436.1 - 0.19 11.4 0.6 15 5.3 0.0 3.4 2 1 2 4 4 4 0 TUP1-like enhancer of split WD40 PF00400.32 RLN10436.1 - 3.3 8.7 7.7 31 5.7 0.1 4.6 5 0 0 5 5 5 0 WD domain, G-beta repeat IFRD PF05004.13 RLN10437.1 - 1.3e-22 80.3 0.5 9.5e-22 77.5 0.8 2.0 1 1 1 2 2 2 1 Interferon-related developmental regulator (IFRD) BrnA_antitoxin PF14384.6 RLN10437.1 - 0.042 14.3 0.2 0.42 11.1 0.0 2.5 2 1 0 2 2 2 0 BrnA antitoxin of type II toxin-antitoxin system Eapp_C PF10238.9 RLN10437.1 - 0.078 13.1 2.6 1.6 8.8 0.3 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein HDAC4_Gln PF12203.8 RLN10437.1 - 0.25 11.5 8.0 0.2 11.9 1.4 2.6 2 1 0 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 Pkinase_Tyr PF07714.17 RLN10438.1 - 4.7e-28 98.2 0.0 8e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN10438.1 - 4e-24 85.4 0.0 8e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RLN10438.1 - 0.00055 19.3 0.0 0.00084 18.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Bac_DNA_binding PF00216.21 RLN10438.1 - 0.02 15.1 0.0 0.055 13.7 0.0 1.8 1 0 0 1 1 1 0 Bacterial DNA-binding protein DUF309 PF03745.14 RLN10438.1 - 0.15 11.8 1.7 0.25 11.1 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF309) Pkinase PF00069.25 RLN10442.1 - 8.5e-67 225.3 0.0 1.1e-66 225.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN10442.1 - 6.2e-31 107.6 0.0 9.6e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN10442.1 - 0.0095 15.3 0.0 0.03 13.6 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 RLN10442.1 - 0.076 13.7 0.2 0.2 12.4 0.2 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain APH PF01636.23 RLN10442.1 - 0.12 12.3 1.6 0.24 11.3 1.6 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN10442.1 - 0.2 10.6 0.1 0.24 10.3 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain GPCR_chapero_1 PF11904.8 RLN10443.1 - 4.5e-31 108.4 12.6 2.6e-20 73.1 3.7 3.3 2 2 0 2 2 2 2 GPCR-chaperone Ank PF00023.30 RLN10443.1 - 7.5e-07 29.3 1.1 0.0011 19.4 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 RLN10443.1 - 9.8e-05 22.8 1.5 2.5 8.8 0.1 3.5 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN10443.1 - 0.00031 21.3 0.6 0.0016 19.0 0.6 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN10443.1 - 0.021 15.3 0.4 0.29 11.8 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat AP3D1 PF06375.11 RLN10443.1 - 1.5 9.0 10.5 0.67 10.2 0.5 3.0 3 0 0 3 3 3 0 AP-3 complex subunit delta-1 Myc_N PF01056.18 RLN10444.1 - 0.027 14.4 0.4 0.035 14.0 0.4 1.0 1 0 0 1 1 1 0 Myc amino-terminal region MRC1 PF09444.10 RLN10446.1 - 6.6e-09 36.4 15.0 6.6e-09 36.4 15.0 6.7 4 1 1 5 5 5 1 MRC1-like domain FANC_SAP PF18081.1 RLN10446.1 - 1.1 9.5 9.4 4 7.7 0.6 3.8 3 0 0 3 3 3 0 Fanconi anemia-associated nuclease SAP domain TTL PF03133.15 RLN10454.1 - 4.4e-77 259.1 0.0 5.5e-77 258.8 0.0 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RLN10454.1 - 5.6e-07 29.1 0.0 0.0015 17.9 0.0 2.5 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RLN10454.1 - 0.00075 18.8 0.0 0.0087 15.3 0.0 2.1 2 1 0 2 2 2 1 Sugar-transfer associated ATP-grasp PX PF00787.24 RLN10455.1 - 0.00014 21.8 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 PX domain zf-MYND PF01753.18 RLN10457.1 - 6.7e-11 42.1 10.0 6.7e-11 42.1 10.0 2.9 2 1 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 RLN10457.1 - 0.0044 17.3 6.1 0.0044 17.3 6.1 2.4 2 1 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding NST1 PF13945.6 RLN10457.1 - 1.6 8.8 8.4 0.67 10.0 3.3 2.5 2 0 0 2 2 2 0 Salt tolerance down-regulator ELO PF01151.18 RLN10465.1 - 4.5e-33 114.8 24.7 3.2e-32 112.0 24.7 1.9 1 1 0 1 1 1 1 GNS1/SUR4 family Ank_4 PF13637.6 RLN10470.1 - 5.4e-41 138.4 16.5 8.9e-06 26.2 0.2 11.0 10 1 1 11 11 11 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN10470.1 - 2.1e-39 134.0 9.8 3.7e-08 33.8 0.3 6.9 3 2 2 7 7 7 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN10470.1 - 9.5e-31 105.5 22.5 0.0013 19.0 0.1 13.6 4 2 10 14 14 14 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN10470.1 - 5.4e-24 81.7 18.5 0.83 10.4 0.0 15.5 14 3 3 17 17 15 5 Ankyrin repeat DUF5049 PF16468.5 RLN10470.1 - 2.3e-05 24.2 0.0 43 4.1 0.0 7.4 7 2 3 10 10 10 0 Domain of unknown function (DUF5049) Ank PF00023.30 RLN10470.1 - 0.00038 20.8 5.7 56 4.4 0.0 8.0 5 3 1 6 6 6 0 Ankyrin repeat DUF1843 PF08898.10 RLN10470.1 - 0.00078 19.9 6.1 37 4.9 0.0 6.8 7 0 0 7 7 7 0 Domain of unknown function (DUF1843) FBD PF08387.10 RLN10470.1 - 0.12 12.3 2.5 27 4.8 0.0 5.2 6 1 0 6 6 6 0 FBD DUF3322 PF11795.8 RLN10470.1 - 0.22 11.5 6.0 52 3.8 0.4 5.5 2 1 4 6 6 6 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) UPF0489 PF12640.7 RLN10470.1 - 2.5 8.3 5.5 10 6.3 0.2 4.1 3 1 0 4 4 4 0 UPF0489 domain DUF1987 PF09345.10 RLN10470.1 - 8.3 6.1 7.0 59 3.4 0.1 5.1 3 1 3 7 7 7 0 Domain of unknown function (DUF1987) PIN_8 PF18476.1 RLN10471.1 - 0.83 9.5 4.7 0.6 9.9 1.6 1.9 1 1 1 2 2 2 0 PIN like domain DARPP-32 PF05395.12 RLN10471.1 - 0.87 9.8 3.9 2 8.6 3.7 1.7 1 1 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Aa_trans PF01490.18 RLN10474.1 - 1.4e-57 195.3 26.0 1.7e-57 195.0 26.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 RLN10474.1 - 0.00015 21.0 13.7 0.00015 21.0 13.7 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF4212 PF13937.6 RLN10474.1 - 0.018 15.4 0.3 0.018 15.4 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) LicD PF04991.13 RLN10475.1 - 9.9e-05 22.6 0.0 0.0086 16.2 0.0 2.1 2 0 0 2 2 2 2 LicD family MULE PF10551.9 RLN10476.1 - 0.00048 20.5 0.2 0.0014 19.0 0.1 1.9 2 0 0 2 2 2 1 MULE transposase domain pPIWI_RE_Y PF18156.1 RLN10476.1 - 0.095 13.1 0.2 0.24 11.8 0.0 1.8 2 0 0 2 2 2 0 pPIWI_RE three-gene island domain Y NAM-associated PF14303.6 RLN10477.1 - 0.046 14.4 2.5 0.96 10.1 2.5 2.5 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain ATG16 PF08614.11 RLN10478.1 - 0.014 15.7 2.8 0.021 15.1 2.8 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 RLN10478.1 - 0.043 14.0 1.4 0.13 12.5 1.3 1.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 RLN10478.1 - 0.24 11.2 0.5 2.8 7.8 0.0 2.1 2 0 0 2 2 2 0 Septum formation initiator APG6_N PF17675.1 RLN10478.1 - 0.31 11.6 4.4 0.65 10.5 4.5 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region TolA_bind_tri PF16331.5 RLN10478.1 - 2.8 8.1 7.3 1.1 9.4 1.3 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation PP2C PF00481.21 RLN10502.1 - 3e-49 168.0 0.0 1.3e-47 162.6 0.0 2.5 1 1 0 1 1 1 1 Protein phosphatase 2C PH PF00169.29 RLN10502.1 - 2.3e-11 44.1 0.0 1.3e-10 41.8 0.0 2.1 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN10502.1 - 3.3e-06 27.5 0.1 6.6e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PP2C_2 PF13672.6 RLN10502.1 - 0.00048 19.8 0.2 0.0024 17.5 0.2 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C ParA PF10609.9 RLN10503.1 - 9.6e-27 94.0 0.1 3.4e-16 59.4 0.1 2.0 1 1 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase AAA_26 PF13500.6 RLN10503.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain Voltage_CLC PF00654.20 RLN10505.1 - 1.6e-74 251.3 33.5 2.9e-74 250.4 33.5 1.4 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 RLN10505.1 - 1.4e-05 25.4 0.1 0.15 12.6 0.0 2.5 2 0 0 2 2 2 2 CBS domain BRX PF08381.11 RLN10506.1 - 0.011 15.0 0.2 0.011 15.0 0.2 2.2 2 0 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 Pkinase PF00069.25 RLN10509.1 - 0.0018 17.7 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 RLN10509.1 - 0.031 13.6 0.0 0.075 12.4 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Retrotran_gag_2 PF14223.6 RLN10510.1 - 3.5e-06 26.7 0.0 6.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF3561 PF12084.8 RLN10511.1 - 0.41 10.7 4.8 0.18 11.8 0.7 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3561) LRR_8 PF13855.6 RLN10520.1 - 0.011 15.5 0.5 0.26 11.1 0.0 2.3 1 1 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 RLN10520.1 - 0.03 14.7 0.2 1.4 9.5 0.0 2.3 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) Cutinase PF01083.22 RLN10521.1 - 1.2e-42 145.9 2.5 1.4e-42 145.6 2.5 1.0 1 0 0 1 1 1 1 Cutinase DUF1744 PF08490.12 RLN10522.1 - 9e-97 324.2 0.0 1.6e-96 323.3 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) Fer4_10 PF13237.6 RLN10522.1 - 0.037 14.1 1.5 0.11 12.6 1.5 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain SH3_9 PF14604.6 RLN10537.1 - 2.2e-09 37.0 0.3 4.1e-09 36.1 0.3 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RLN10537.1 - 2.8e-08 33.2 0.1 5e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 SH3 domain LIM PF00412.22 RLN10537.1 - 4.1e-07 30.1 6.0 5e-07 29.8 0.1 3.2 4 0 0 4 4 4 1 LIM domain SH3_2 PF07653.17 RLN10537.1 - 6.5e-06 25.7 0.0 1.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DZR PF12773.7 RLN10537.1 - 1.4e-05 25.0 7.2 0.00013 21.9 1.9 3.0 3 0 0 3 3 3 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 RLN10537.1 - 0.00063 19.4 2.7 0.00063 19.4 2.7 2.1 2 0 0 2 2 2 1 zinc-ribbon domain SH3_3 PF08239.11 RLN10537.1 - 0.004 17.4 0.4 0.012 15.8 0.1 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain UPF0547 PF10571.9 RLN10537.1 - 0.041 14.0 3.1 0.11 12.6 3.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zinc_ribbon_15 PF17032.5 RLN10537.1 - 0.046 14.5 2.5 0.046 14.5 2.5 2.2 3 0 0 3 3 3 0 zinc-ribbon family zf-ribbon_3 PF13248.6 RLN10537.1 - 0.26 10.7 5.8 0.32 10.5 2.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.6 RLN10537.1 - 1.1 9.3 10.3 4 7.5 0.2 3.6 4 0 0 4 4 4 0 Nudix N-terminal NinF PF05810.12 RLN10537.1 - 2.9 7.8 5.7 4.6 7.2 0.4 2.6 3 0 0 3 3 3 0 NinF protein DUF3391 PF11871.8 RLN10538.1 - 1.8 9.1 8.9 4.2 7.9 3.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) SNF2_N PF00176.23 RLN10539.1 - 2.7e-54 184.2 0.0 8.4e-54 182.6 0.0 1.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain DUF3535 PF12054.8 RLN10539.1 - 6.3e-18 65.2 0.1 2.4e-16 60.1 0.2 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3535) Helicase_C PF00271.31 RLN10539.1 - 4.9e-16 59.0 0.0 1.1e-14 54.6 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN10539.1 - 2.6e-06 27.5 0.0 1.2e-05 25.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RLN10539.1 - 0.0037 17.0 0.0 0.012 15.3 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase CLASP_N PF12348.8 RLN10539.1 - 0.035 13.7 0.1 0.09 12.3 0.1 1.7 1 0 0 1 1 1 0 CLASP N terminal ERCC3_RAD25_C PF16203.5 RLN10539.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase HEAT_EZ PF13513.6 RLN10539.1 - 0.11 13.0 2.1 0.38 11.3 0.0 3.2 4 1 0 4 4 4 0 HEAT-like repeat HTH_OrfB_IS605 PF12323.8 RLN10540.1 - 5.9e-09 35.3 1.9 1.3e-08 34.1 1.9 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain OrfB_IS605 PF01385.19 RLN10540.1 - 6.1e-07 29.7 0.0 1.5e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Probable transposase Alpha_adaptinC2 PF02883.20 RLN10540.1 - 0.14 12.4 0.6 0.31 11.4 0.6 1.4 1 0 0 1 1 1 0 Adaptin C-terminal domain Cadherin PF00028.17 RLN10541.1 - 0 1554.3 113.4 5.1e-15 55.7 0.1 71.7 72 0 0 72 72 72 65 Cadherin domain Cadherin_4 PF17803.1 RLN10541.1 - 5.6e-48 161.4 394.2 0.00063 20.3 0.5 61.5 66 1 1 67 67 67 32 Bacterial cadherin-like domain Big_9 PF17963.1 RLN10541.1 - 9.2e-47 157.7 430.5 0.00028 21.6 1.0 63.5 63 4 2 65 65 65 34 Bacterial Ig domain TIG PF01833.24 RLN10541.1 - 1.2e-27 95.8 92.0 1.4e-09 37.8 1.8 18.8 16 3 1 17 17 17 9 IPT/TIG domain Cadherin_3 PF16184.5 RLN10541.1 - 1.1e-05 25.4 80.5 1.5 8.8 0.0 27.2 31 1 1 32 32 32 2 Cadherin-like TRP PF06011.12 RLN10541.1 - 1.8 7.2 23.5 0.11 11.2 14.8 2.5 1 1 0 2 2 2 0 Transient receptor potential (TRP) ion channel ChitinaseA_N PF08329.10 RLN10541.1 - 7.5 6.2 23.2 0.26 11.0 0.0 9.8 15 0 0 15 15 15 0 Chitinase A, N-terminal domain PDZ_1 PF12812.7 RLN10542.1 - 2.4e-30 104.3 0.0 8.2e-23 80.2 0.0 2.9 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 RLN10542.1 - 1.6e-16 61.6 0.1 1.9e-15 58.1 0.0 2.5 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_6 PF17820.1 RLN10542.1 - 3e-13 49.4 0.0 0.031 14.1 0.0 4.6 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 RLN10542.1 - 2.8e-10 40.4 0.0 0.0034 17.7 0.0 4.3 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.24 RLN10542.1 - 6.2e-06 26.5 0.0 0.26 11.7 0.0 3.5 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 RLN10542.1 - 0.0055 16.7 0.0 1.1 9.3 0.2 3.8 4 0 0 4 4 4 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 RLN10542.1 - 0.052 12.2 0.8 0.068 11.8 0.1 1.4 2 0 0 2 2 2 0 Peptidase S46 DUF31 PF01732.16 RLN10542.1 - 0.087 12.3 0.2 0.12 11.8 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) PHD PF00628.29 RLN10543.1 - 0.00012 21.9 5.3 0.0006 19.7 5.3 2.1 1 1 0 1 1 1 1 PHD-finger C1_1 PF00130.22 RLN10543.1 - 0.025 14.4 6.7 0.048 13.6 3.2 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TPR_2 PF07719.17 RLN10543.1 - 2.9 8.2 12.8 15 6.0 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 RLN10543.1 - 4 7.7 7.2 10 6.4 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat PAP2 PF01569.21 RLN10545.1 - 1.4e-13 50.8 7.7 5.8e-12 45.5 7.7 2.3 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 RLN10545.1 - 0.0047 17.1 0.9 0.041 14.0 0.1 2.2 1 1 1 2 2 2 1 Divergent PAP2 family ThrE PF06738.12 RLN10545.1 - 0.14 11.5 4.0 0.23 10.8 4.0 1.3 1 0 0 1 1 1 0 Putative threonine/serine exporter UbiA PF01040.18 RLN10545.1 - 1.3 8.3 11.6 2.3 7.4 11.5 1.6 1 1 0 1 1 1 0 UbiA prenyltransferase family GtrA PF04138.14 RLN10545.1 - 1.9 8.8 10.5 2.5 8.4 0.9 2.6 1 1 2 3 3 3 0 GtrA-like protein PAP2 PF01569.21 RLN10546.1 - 0.47 10.2 7.7 0.17 11.6 3.4 2.3 2 1 0 2 2 2 0 PAP2 superfamily PX PF00787.24 RLN10547.1 - 0.082 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 PX domain DHHW PF14286.6 RLN10547.1 - 0.099 11.9 0.0 0.46 9.8 0.0 1.8 2 0 0 2 2 2 0 DHHW protein MMR1 PF08505.10 RLN10550.1 - 5.2 7.3 13.4 1.3 9.3 10.5 1.4 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Glucan_synthase PF02364.15 RLN10566.1 - 1.1e-145 486.9 6.2 4.2e-127 425.5 2.1 2.5 1 1 1 2 2 2 2 1,3-beta-glucan synthase component PhoU_div PF01865.16 RLN10566.1 - 0.12 11.7 0.9 0.25 10.7 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF47 DUF1201 PF06716.11 RLN10566.1 - 0.43 10.6 5.3 11 6.1 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) COPI_assoc PF08507.10 RLN10567.1 - 7.9e-09 35.7 1.5 1e-08 35.3 1.5 1.2 1 0 0 1 1 1 1 COPI associated protein DUF3805 PF12712.7 RLN10568.1 - 0.077 13.2 0.3 0.13 12.4 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3805) UPF0242 PF06785.11 RLN10569.1 - 0.0051 17.0 1.0 0.0051 17.0 1.0 3.7 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Sipho_Gp37 PF14594.6 RLN10569.1 - 0.034 13.2 0.2 0.072 12.1 0.2 1.5 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein TMF_DNA_bd PF12329.8 RLN10569.1 - 4.3 7.4 19.8 0.2 11.6 8.4 3.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding GIT_CC PF16559.5 RLN10569.1 - 4.7 7.1 23.4 2.1 8.3 7.5 4.2 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor TagF_N PF09867.9 RLN10570.1 - 0.037 14.1 0.0 0.052 13.6 0.0 1.2 1 0 0 1 1 1 0 TagF N-terminal domain, Type VI secretion system-associated GAF_2 PF13185.6 RLN10572.1 - 7.7e-06 26.2 0.0 1.5e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 GAF domain Med26 PF08711.11 RLN10572.1 - 0.056 13.5 0.2 0.14 12.2 0.2 1.7 1 0 0 1 1 1 0 TFIIS helical bundle-like domain GAF PF01590.26 RLN10572.1 - 0.088 13.4 0.0 0.23 12.1 0.0 1.7 1 0 0 1 1 1 0 GAF domain ERM PF00769.19 RLN10572.1 - 2.1 8.1 10.1 0.34 10.7 6.3 1.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family SOG2 PF10428.9 RLN10572.1 - 8.2 5.5 21.1 13 4.8 21.1 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 RLN10572.1 - 9.9 6.0 10.0 16 5.3 10.0 1.4 1 0 0 1 1 1 0 SPX domain FYVE PF01363.21 RLN10573.1 - 6.6e-09 35.8 14.7 1.9e-07 31.1 12.6 3.1 3 0 0 3 3 3 1 FYVE zinc finger GAF_2 PF13185.6 RLN10573.1 - 1e-07 32.3 0.2 2.3e-07 31.2 0.2 1.6 1 0 0 1 1 1 1 GAF domain DEP PF00610.21 RLN10573.1 - 1.6e-06 28.0 0.0 3.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GAF PF01590.26 RLN10573.1 - 0.0033 18.0 0.4 0.0087 16.7 0.4 1.8 1 0 0 1 1 1 1 GAF domain PH_4 PF15404.6 RLN10573.1 - 0.0048 16.7 1.1 0.0097 15.7 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Urb2 PF10441.9 RLN10573.1 - 0.016 15.1 0.6 0.035 14.0 0.6 1.5 1 0 0 1 1 1 0 Urb2/Npa2 family PH PF00169.29 RLN10573.1 - 0.019 15.4 0.0 0.039 14.5 0.0 1.5 1 0 0 1 1 1 0 PH domain Leu_zip PF15294.6 RLN10573.1 - 0.026 14.0 4.0 0.041 13.4 4.0 1.2 1 0 0 1 1 1 0 Leucine zipper Filament PF00038.21 RLN10573.1 - 0.6 9.6 7.2 0.91 9.0 7.2 1.1 1 0 0 1 1 1 0 Intermediate filament protein RIX1 PF08167.12 RLN10574.1 - 4.2e-17 62.5 6.1 5.9e-17 62.0 4.8 1.9 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis MMS19_C PF12460.8 RLN10574.1 - 0.00013 21.2 1.1 0.00024 20.3 1.1 1.3 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal Dopey_N PF04118.14 RLN10574.1 - 0.0014 17.8 0.4 0.0023 17.1 0.4 1.3 1 0 0 1 1 1 1 Dopey, N-terminal Goodbye PF17109.5 RLN10574.1 - 0.011 16.1 0.5 5.7 7.4 0.1 3.0 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain DUF1018 PF06252.12 RLN10574.1 - 0.46 11.5 9.3 0.55 11.2 0.5 4.3 3 2 1 4 4 4 0 Protein of unknown function (DUF1018) Mg_trans_NIPA PF05653.14 RLN10575.1 - 1.1e-29 103.5 16.5 6.9e-15 54.9 1.2 3.0 2 1 0 2 2 2 2 Magnesium transporter NIPA ERGIC_N PF13850.6 RLN10575.1 - 0.32 11.4 1.1 7.5 7.0 0.4 3.1 2 1 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sulfate_transp PF00916.20 RLN10575.1 - 1.9 7.2 11.0 0.02 13.7 2.0 2.1 2 1 0 2 2 2 0 Sulfate permease family Sugarporin_N PF11471.8 RLN10575.1 - 3.7 7.6 5.8 25 4.9 2.2 3.3 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension Pkinase PF00069.25 RLN10576.1 - 4.7e-63 213.0 0.0 8.3e-63 212.2 0.0 1.3 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN10576.1 - 5.5e-29 101.2 0.4 2.1e-28 99.3 0.4 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN10576.1 - 0.015 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Elicitin PF00964.17 RLN10629.1 - 7.6e-25 86.8 8.2 9.3e-25 86.6 8.2 1.1 1 0 0 1 1 1 1 Elicitin ANF_receptor PF01094.28 RLN10629.1 - 0.25 10.4 4.0 0.34 10.0 4.0 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region Elicitin PF00964.17 RLN10630.1 - 5.8e-24 84.0 6.0 7.1e-24 83.7 6.0 1.1 1 0 0 1 1 1 1 Elicitin Elicitin PF00964.17 RLN10631.1 - 2.5e-24 85.2 8.1 3e-24 84.9 8.1 1.1 1 0 0 1 1 1 1 Elicitin ANF_receptor PF01094.28 RLN10631.1 - 0.13 11.4 3.8 0.17 11.0 3.8 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region Elicitin PF00964.17 RLN10632.1 - 4.8e-24 84.3 8.5 5.9e-24 84.0 8.5 1.1 1 0 0 1 1 1 1 Elicitin ANF_receptor PF01094.28 RLN10632.1 - 0.12 11.4 3.9 0.16 11.0 3.9 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region Sulfotransfer_3 PF13469.6 RLN10633.1 - 1.5e-09 38.6 2.5 2e-09 38.2 0.1 2.5 3 1 0 4 4 4 1 Sulfotransferase family Asp_Arg_Hydrox PF05118.15 RLN10633.1 - 3.4e-08 33.4 0.1 6.7e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Sulfotransfer_1 PF00685.27 RLN10633.1 - 1.1e-07 31.7 0.0 2.5e-06 27.2 0.0 2.5 1 1 0 1 1 1 1 Sulfotransferase domain Elicitin PF00964.17 RLN10634.1 - 6.4e-24 83.9 7.4 1e-23 83.2 7.4 1.3 1 0 0 1 1 1 1 Elicitin PT PF04886.12 RLN10634.1 - 0.00068 19.1 7.9 0.00068 19.1 7.9 2.0 2 0 0 2 2 2 1 PT repeat ANF_receptor PF01094.28 RLN10634.1 - 0.23 10.5 3.9 0.31 10.1 3.9 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region REJ PF02010.15 RLN10635.1 - 5.8e-53 180.3 2.3 3e-49 168.1 2.5 2.3 1 1 1 2 2 2 2 REJ domain Tetraspanin PF00335.20 RLN10635.1 - 2.9e-11 43.5 65.7 2.3e-08 34.1 2.4 6.7 8 0 0 8 8 8 5 Tetraspanin family DUF1084 PF06454.11 RLN10635.1 - 3.1e-07 30.0 8.5 1.6e-06 27.7 8.4 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) RWP-RK PF02042.15 RLN10637.1 - 6.3e-12 45.3 0.0 1.2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain HTH_6 PF01418.17 RLN10637.1 - 0.012 15.6 0.3 0.034 14.1 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family NUMOD1 PF07453.13 RLN10637.1 - 0.065 13.5 0.0 0.47 10.8 0.0 2.2 2 0 0 2 2 2 0 NUMOD1 domain HTH_8 PF02954.19 RLN10637.1 - 0.4 10.5 2.2 0.46 10.3 0.0 2.2 2 1 1 3 3 3 0 Bacterial regulatory protein, Fis family TPR_16 PF13432.6 RLN10638.1 - 3.6e-11 43.5 1.6 3.2e-07 30.9 0.6 3.6 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN10638.1 - 1.1e-10 40.8 0.1 0.0012 18.8 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN10638.1 - 2.5e-08 34.1 3.7 0.00086 19.9 0.3 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN10638.1 - 1.5e-07 31.0 0.1 0.0076 15.9 0.0 2.6 1 1 1 2 2 2 2 TPR repeat TPR_12 PF13424.6 RLN10638.1 - 2.2e-07 31.1 0.8 4.9e-06 26.7 0.1 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN10638.1 - 6.2e-07 29.8 3.3 0.036 14.6 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 RLN10638.1 - 1.5e-06 28.4 2.6 0.013 16.1 0.0 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN10638.1 - 6.8e-05 22.5 0.1 0.67 9.9 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN10638.1 - 0.00011 22.3 0.0 0.048 14.1 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN10638.1 - 0.00019 21.2 1.6 0.15 11.9 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN10638.1 - 0.00028 21.0 0.5 0.00089 19.4 0.5 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN10638.1 - 0.0063 16.6 0.1 0.29 11.5 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat YccV-like PF08755.11 RLN10638.1 - 0.01 16.3 0.0 0.066 13.7 0.0 2.2 1 1 0 1 1 1 0 Hemimethylated DNA-binding protein YccV like ANAPC3 PF12895.7 RLN10638.1 - 0.026 14.7 0.0 0.077 13.2 0.0 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1330 PF07045.11 RLN10638.1 - 0.031 14.6 0.2 0.34 11.3 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1330) SH3_2 PF07653.17 RLN10638.1 - 0.041 13.6 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain TPR_7 PF13176.6 RLN10638.1 - 0.054 13.5 0.5 23 5.3 0.0 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 RLN10638.1 - 0.06 14.0 2.9 0.67 10.8 1.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Type_III_YscG PF09477.10 RLN10638.1 - 0.1 12.6 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) YfdX PF10938.8 RLN10638.1 - 0.19 11.6 0.7 0.85 9.5 0.0 2.1 2 0 0 2 2 2 0 YfdX protein RPN7 PF10602.9 RLN10639.1 - 5.5e-23 81.6 1.5 2e-14 53.7 0.7 3.2 2 1 0 2 2 2 2 26S proteasome subunit RPN7 PCI PF01399.27 RLN10639.1 - 2.9e-15 56.7 0.3 1.9e-14 54.1 0.1 2.2 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 RLN10639.1 - 0.0023 17.9 0.0 0.0063 16.6 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN10639.1 - 0.044 14.1 0.0 0.16 12.3 0.0 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN10639.1 - 0.046 13.6 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat IQ PF00612.27 RLN10642.1 - 1.6e-08 33.6 0.8 0.0062 16.2 0.0 3.0 2 0 0 2 2 2 2 IQ calmodulin-binding motif MitMem_reg PF13012.6 RLN10642.1 - 0.034 14.6 0.1 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Fmp27_WPPW PF10359.9 RLN10643.1 - 0.006 15.5 3.5 0.006 15.5 3.5 2.8 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain NPV_P10 PF05531.12 RLN10643.1 - 0.012 16.0 13.2 0.16 12.5 1.5 5.2 5 1 0 6 6 6 0 Nucleopolyhedrovirus P10 protein TMPIT PF07851.13 RLN10643.1 - 0.026 13.8 12.1 0.05 12.9 0.3 2.9 4 0 0 4 4 4 0 TMPIT-like protein DELLA PF12041.8 RLN10643.1 - 0.059 13.3 0.3 0.4 10.6 0.1 2.6 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal Occludin_ELL PF07303.13 RLN10643.1 - 0.29 11.9 14.1 1.2 9.9 1.3 4.8 4 1 1 5 5 5 0 Occludin homology domain DEDD_Tnp_IS110 PF01548.17 RLN10643.1 - 1.9 8.3 5.5 0.37 10.7 1.0 2.1 2 0 0 2 2 2 0 Transposase BCDHK_Adom3 PF10436.9 RLN10644.1 - 3.1e-53 179.9 0.0 4.4e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 RLN10644.1 - 1.8e-13 51.0 0.0 3.9e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 RLN10644.1 - 0.00019 21.3 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2691 PF10903.8 RLN10645.1 - 0.054 13.4 0.1 0.064 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2691) CwfJ_C_1 PF04677.15 RLN10646.1 - 5.5e-31 107.0 0.5 1.1e-30 106.0 0.5 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 RLN10646.1 - 1e-27 96.9 0.0 4.9e-27 94.7 0.0 2.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Microvir_J PF04726.13 RLN10646.1 - 0.15 12.1 1.5 0.49 10.4 1.5 1.9 1 0 0 1 1 1 0 Microvirus J protein B2-adapt-app_C PF09066.10 RLN10647.1 - 8.2e-07 29.1 0.3 2.5e-06 27.6 0.1 1.9 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain Herpes_teg_N PF04843.12 RLN10647.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region N_BRCA1_IG PF16158.5 RLN10648.1 - 3.7e-34 117.5 0.1 1.2e-33 115.9 0.0 1.9 2 0 0 2 2 2 1 Ig-like domain from next to BRCA1 gene PB1 PF00564.24 RLN10648.1 - 6.5e-08 32.4 0.1 3.5e-07 30.1 0.0 2.2 2 1 1 3 3 3 1 PB1 domain RabGAP-TBC PF00566.18 RLN10649.1 - 4.3e-32 111.5 0.1 8.5e-32 110.6 0.1 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain zf-rbx1 PF12678.7 RLN10650.1 - 2.2e-08 34.3 0.3 2.2e-08 34.3 0.3 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 RLN10650.1 - 9.8e-06 25.8 2.1 9.8e-06 25.8 2.1 2.3 2 0 0 2 2 2 1 Ring finger domain PHD PF00628.29 RLN10650.1 - 4.7e-05 23.2 3.7 4.7e-05 23.2 3.7 2.4 2 0 0 2 2 2 1 PHD-finger zf-C3HC4_2 PF13923.6 RLN10650.1 - 6.4e-05 22.7 1.4 0.00015 21.5 1.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN10650.1 - 0.00034 20.4 0.1 0.00034 20.4 0.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN10650.1 - 0.00067 19.4 1.2 0.0016 18.1 1.2 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 RLN10650.1 - 0.0019 18.2 0.4 0.0019 18.2 0.4 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD_2 PF13831.6 RLN10650.1 - 0.0024 17.4 1.2 0.0024 17.4 1.2 1.8 2 0 0 2 2 2 1 PHD-finger zf-RING_4 PF14570.6 RLN10650.1 - 0.25 11.2 0.8 0.52 10.2 0.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 RLN10650.1 - 0.27 11.6 7.9 2.4 8.5 1.4 2.5 2 0 0 2 2 2 0 RING-like domain zf-C3H2C3 PF17122.5 RLN10650.1 - 0.4 10.8 1.9 1.1 9.3 1.9 1.8 1 0 0 1 1 1 0 Zinc-finger Prok-RING_4 PF14447.6 RLN10650.1 - 1 9.3 7.4 0.13 12.2 0.6 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 RLN10650.1 - 3.5 7.5 6.7 0.88 9.5 0.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.6 RLN10650.1 - 9.5 6.6 9.3 0.73 10.1 0.8 2.6 2 1 0 2 2 2 0 PHD-like zinc-binding domain Chitin_synth_1 PF01644.17 RLN10657.1 - 3.1e-45 154.1 0.0 4.7e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 RLN10657.1 - 6.9e-23 81.0 0.0 3.3e-22 78.8 0.0 1.8 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 RLN10657.1 - 7.1e-14 52.2 0.0 1.4e-13 51.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 MIT PF04212.18 RLN10657.1 - 7.5e-13 48.3 0.1 1.6e-12 47.3 0.1 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Glyco_tranf_2_3 PF13641.6 RLN10657.1 - 1.4e-11 44.7 0.0 3.4e-11 43.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Chitin_synth_1N PF08407.11 RLN10657.1 - 2.1e-10 40.4 0.1 7.2e-10 38.7 0.1 2.0 2 0 0 2 2 2 1 Chitin synthase N-terminal NADH5_C PF06455.11 RLN10657.1 - 4.9 6.7 11.2 0.71 9.4 3.6 2.6 3 0 0 3 3 3 0 NADH dehydrogenase subunit 5 C-terminus Oxidored_FMN PF00724.20 RLN10658.1 - 3.3e-82 276.5 0.0 3.7e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 RLN10659.1 - 2.3e-29 102.7 0.0 2.5e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TBCC PF07986.12 RLN10704.1 - 2.3e-30 104.8 0.1 3.8e-30 104.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 RLN10704.1 - 4.2e-19 69.1 0.2 4.2e-19 69.1 0.2 2.2 2 1 0 2 2 2 1 Tubulin-specific chaperone C N-terminal domain CAP_GLY PF01302.25 RLN10704.1 - 8.9e-18 64.1 0.0 1.8e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain DUF4604 PF15377.6 RLN10705.1 - 0.072 13.5 16.1 0.08 13.4 16.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RPA43_OB PF17875.1 RLN10705.1 - 0.47 11.1 10.2 1.1 9.9 0.0 3.3 2 2 1 3 3 3 0 RPA43 OB domain in RNA Pol I Med19 PF10278.9 RLN10705.1 - 6.7 6.6 18.6 9.2 6.2 18.6 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Protocadherin PF08374.11 RLN10705.1 - 8.7 6.3 12.3 13 5.7 12.3 1.4 1 1 0 1 1 1 0 Protocadherin WW PF00397.26 RLN10711.1 - 1.2e-21 76.4 15.2 5.7e-08 32.7 3.9 3.8 3 0 0 3 3 3 3 WW domain Ank_2 PF12796.7 RLN10711.1 - 7.8e-20 71.3 0.2 3.4e-12 46.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RLN10711.1 - 9.8e-16 57.4 1.1 7e-06 26.2 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 RLN10711.1 - 1.8e-13 49.3 0.3 0.0021 18.4 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 RLN10711.1 - 3.2e-11 43.5 0.6 2.4e-10 40.7 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN10711.1 - 1.7e-06 28.2 0.1 8.5e-05 22.8 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Glyco_hyd_101C PF17451.2 RLN10711.1 - 0.057 13.7 5.8 0.25 11.6 0.1 3.8 4 0 0 4 4 4 0 Glycosyl hydrolase 101 beta sandwich domain Acetyltransf_6 PF13480.7 RLN10711.1 - 0.36 11.0 4.1 0.39 10.9 0.7 2.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SecA_SW PF07516.13 RLN10711.1 - 0.51 10.4 8.7 1.2 9.1 8.7 1.6 1 0 0 1 1 1 0 SecA Wing and Scaffold domain Prefoldin PF02996.17 RLN10712.1 - 1.2e-21 76.8 1.6 9.7e-21 73.9 1.6 2.0 1 1 0 1 1 1 1 Prefoldin subunit EF1_GNE PF00736.19 RLN10713.1 - 7.6e-32 109.4 1.2 1.3e-31 108.6 1.2 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain Ribosomal_60s PF00428.19 RLN10713.1 - 5.2e-05 23.7 10.6 5.2e-05 23.7 10.6 2.9 3 1 1 4 4 3 1 60s Acidic ribosomal protein CDC27 PF09507.10 RLN10713.1 - 0.0053 16.2 12.7 0.0059 16.0 12.7 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Pox_Ag35 PF03286.14 RLN10713.1 - 0.0056 16.5 11.1 0.0083 15.9 11.1 1.2 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Stm1_N PF09598.10 RLN10713.1 - 0.0059 17.4 4.2 0.0059 17.4 4.2 2.4 2 1 0 2 2 1 1 Stm1 EF-1_beta_acid PF10587.9 RLN10713.1 - 0.0076 16.7 12.2 0.0076 16.7 12.2 3.6 3 2 0 3 3 2 1 Eukaryotic elongation factor 1 beta central acidic region PBP1_TM PF14812.6 RLN10713.1 - 0.026 14.9 6.7 0.053 13.9 6.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal VIR_N PF15912.5 RLN10713.1 - 0.029 14.0 4.0 0.037 13.6 4.0 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal CENP-B_dimeris PF09026.10 RLN10713.1 - 0.78 10.2 10.0 1.5 9.3 10.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Red1 PF07964.11 RLN10713.1 - 0.93 7.7 7.5 1.1 7.4 7.5 1.0 1 0 0 1 1 1 0 Rec10 / Red1 FAM176 PF14851.6 RLN10713.1 - 1.2 8.7 5.5 2.1 8.0 5.5 1.4 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 RLN10713.1 - 2.8 6.1 8.0 3.6 5.8 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2868 PF11067.8 RLN10713.1 - 3 7.3 6.1 3.7 7.0 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) DNA_pol_phi PF04931.13 RLN10713.1 - 8.2 4.4 11.7 10 4.0 11.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi PAC1 PF16094.5 RLN10713.1 - 9.2 5.3 6.9 17 4.5 6.9 1.4 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Methyltransf_16 PF10294.9 RLN10714.1 - 4.1e-29 101.5 0.1 9.1e-29 100.4 0.0 1.6 2 0 0 2 2 2 1 Lysine methyltransferase MFS_2 PF13347.6 RLN10714.1 - 2.8e-07 29.5 10.5 2.8e-07 29.5 10.5 2.5 2 0 0 2 2 2 1 MFS/sugar transport protein Methyltransf_25 PF13649.6 RLN10714.1 - 0.00022 21.9 0.1 0.006 17.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 RLN10714.1 - 0.0025 17.4 0.0 0.0074 15.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain GidB PF02527.15 RLN10714.1 - 0.024 14.0 0.0 0.055 12.8 0.0 1.5 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 RLN10714.1 - 0.038 13.8 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 RLN10714.1 - 0.073 13.8 0.0 1.4 9.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 RLN10714.1 - 0.075 12.2 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Met_10 PF02475.16 RLN10714.1 - 0.081 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein DUF938 PF06080.12 RLN10714.1 - 0.094 12.5 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_23 PF13489.6 RLN10714.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SPX PF03105.19 RLN10715.1 - 7.9 6.3 11.8 11 5.8 11.8 1.3 1 0 0 1 1 1 0 SPX domain LRR_4 PF12799.7 RLN10716.1 - 1.3e-22 79.5 17.9 3.5e-07 30.4 0.8 5.6 5 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN10716.1 - 2.6e-17 62.3 21.7 1.9e-07 30.7 0.3 5.1 5 0 0 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 RLN10716.1 - 6.8e-12 45.2 6.8 1.6e-08 34.3 0.6 3.9 2 2 2 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 RLN10716.1 - 1.6e-06 27.7 12.8 1.1 9.5 0.2 7.3 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 RLN10716.1 - 0.15 12.7 13.4 4.1 8.3 0.0 6.5 7 2 0 7 7 7 0 Leucine Rich Repeat IQ PF00612.27 RLN10728.1 - 1.1e-06 27.9 91.8 0.88 9.5 0.0 16.4 16 0 0 16 16 16 11 IQ calmodulin-binding motif WW PF00397.26 RLN10728.1 - 0.00022 21.2 0.0 0.00098 19.2 0.0 2.2 2 0 0 2 2 2 1 WW domain zf-HIT PF04438.16 RLN10728.1 - 0.0042 16.9 3.3 0.0042 16.9 3.3 5.2 5 1 0 5 5 5 1 HIT zinc finger Styelin PF17562.2 RLN10728.1 - 0.16 12.4 0.7 27 5.2 0.0 2.8 2 0 0 2 2 2 0 Styelin zf-B_box PF00643.24 RLN10728.1 - 1.5 9.0 57.6 0.014 15.6 7.2 5.8 5 0 0 5 5 5 0 B-box zinc finger Bact_lectin PF18483.1 RLN10729.1 - 1.9e-20 73.7 0.0 4.6e-20 72.5 0.0 1.5 2 0 0 2 2 2 1 Bacterial lectin Lectin_legB PF00139.19 RLN10729.1 - 5.2e-15 55.6 0.0 2.7e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain fn3 PF00041.21 RLN10729.1 - 5.6e-06 26.6 0.1 1.3e-05 25.5 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III domain TIG PF01833.24 RLN10729.1 - 0.0074 16.3 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 IPT/TIG domain DUF1899 PF08953.11 RLN10730.1 - 1.2e-23 82.8 0.2 2.1e-23 81.9 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 RLN10730.1 - 6.2e-18 64.4 0.1 1.1e-17 63.7 0.1 1.4 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 RLN10730.1 - 3e-17 62.6 2.5 0.00032 21.4 0.1 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN10730.1 - 5.7e-09 36.2 0.0 3.4e-05 24.1 0.1 3.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN10730.1 - 0.0037 16.3 0.0 0.75 8.7 0.0 2.8 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 RLN10730.1 - 0.09 11.8 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Translin PF01997.16 RLN10731.1 - 4e-17 62.9 0.2 3.4e-16 59.8 0.2 2.1 1 1 0 1 1 1 1 Translin family zf-C2H2_12 PF18658.1 RLN10731.1 - 0.12 12.0 0.3 0.27 10.8 0.3 1.5 1 0 0 1 1 1 0 Zinc-finger C2H2-type ABC_tran PF00005.27 RLN10742.1 - 3.4e-35 121.5 0.0 7.2e-35 120.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 RLN10742.1 - 1.3e-32 113.6 5.2 1.6e-32 113.3 5.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 RLN10742.1 - 1.8e-09 37.4 0.1 5e-07 29.4 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RLN10742.1 - 0.00042 20.7 0.3 0.0023 18.3 0.3 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 RLN10742.1 - 0.0015 19.1 0.4 0.078 13.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 RLN10742.1 - 0.0031 17.3 0.0 0.0049 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 RLN10742.1 - 0.0033 17.3 0.7 0.028 14.2 0.1 2.2 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 RLN10742.1 - 0.0062 15.8 0.0 0.014 14.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 RLN10742.1 - 0.009 16.3 0.1 0.042 14.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.17 RLN10742.1 - 0.011 15.8 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 RLN10742.1 - 0.012 15.3 0.2 0.031 14.0 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 RLN10742.1 - 0.022 13.9 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) G-alpha PF00503.20 RLN10742.1 - 0.027 13.6 0.0 0.051 12.7 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit AAA_24 PF13479.6 RLN10742.1 - 0.028 14.1 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 RLN10742.1 - 0.053 12.5 0.0 0.15 11.0 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FtsK_SpoIIIE PF01580.18 RLN10742.1 - 0.075 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 RLN10742.1 - 0.1 12.7 0.0 0.41 10.7 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 RLN10742.1 - 0.15 12.3 2.1 0.6 10.3 0.2 2.8 2 1 1 3 3 3 0 AAA domain TFIIA PF03153.13 RLN10743.1 - 0.048 13.7 27.5 0.5 10.3 19.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Patatin PF01734.22 RLN10744.1 - 3e-10 40.6 3.7 2e-07 31.4 3.7 2.5 1 1 0 1 1 1 1 Patatin-like phospholipase GlnD_UR_UTase PF08335.11 RLN10744.1 - 0.1 12.7 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase NDUF_B7 PF05676.13 RLN10745.1 - 4.5e-27 93.5 1.3 7.4e-27 92.9 1.3 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 RLN10745.1 - 9.3e-05 22.4 0.8 0.00013 21.9 0.8 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 RLN10745.1 - 0.036 14.4 2.2 0.094 13.0 1.3 1.9 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 AD PF09793.9 RLN10746.1 - 1.9e-21 76.0 0.1 3.1e-21 75.3 0.1 1.3 1 0 0 1 1 1 1 Anticodon-binding domain Gemin6 PF06372.12 RLN10746.1 - 5e-10 39.2 0.1 0.00037 20.1 0.0 2.1 2 0 0 2 2 2 2 Gemin6 protein LSM14 PF12701.7 RLN10746.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Scd6-like Sm domain Zip PF02535.22 RLN10747.1 - 2.4e-27 96.0 9.2 1.2e-26 93.7 9.2 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.22 RLN10748.1 - 2.4e-27 96.1 20.7 1.5e-25 90.1 9.4 2.7 1 1 1 2 2 2 2 ZIP Zinc transporter MtrG PF04210.13 RLN10748.1 - 2.8 7.8 4.6 3.4 7.6 0.4 3.0 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G PfkB PF00294.24 RLN10749.1 - 1.2e-23 83.9 0.3 2.2e-20 73.2 0.1 2.0 1 1 1 2 2 2 2 pfkB family carbohydrate kinase Folate_rec PF03024.14 RLN10751.1 - 9e-09 35.4 3.3 1.2e-08 35.0 3.3 1.2 1 0 0 1 1 1 1 Folate receptor family MCR PF18509.1 RLN10751.1 - 0.025 14.1 0.1 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 Magnetochrome domain CUE PF02845.16 RLN10752.1 - 3.3e-07 29.9 0.0 5.1e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 CUE domain PSD4 PF07631.11 RLN10752.1 - 0.13 12.8 0.2 0.23 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) GYF PF02213.16 RLN10753.1 - 2.9e-05 23.7 0.5 2.9e-05 23.7 0.5 2.2 2 0 0 2 2 2 1 GYF domain CusF_Ec PF11604.8 RLN10753.1 - 0.065 13.2 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF Fcf1 PF04900.12 RLN10754.1 - 1.4e-38 131.2 2.7 2.4e-38 130.5 2.7 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 RLN10754.1 - 5.6e-11 42.8 0.1 1.2e-10 41.7 0.0 1.6 2 0 0 2 2 2 1 PIN like domain Herpes_UL49_2 PF04823.12 RLN10755.1 - 0.022 14.8 0.1 0.082 13.0 0.1 2.0 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein PHD PF00628.29 RLN10765.1 - 2.3e-16 59.4 51.5 5.3e-08 32.6 9.4 4.5 4 0 0 4 4 4 3 PHD-finger WSD PF15613.6 RLN10765.1 - 3.8e-15 56.2 0.0 3.8e-15 56.2 0.0 3.7 4 1 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 RLN10765.1 - 1.2e-11 44.8 2.9 1.2e-11 44.8 2.9 2.3 3 0 0 3 3 3 1 DDT domain PHD_2 PF13831.6 RLN10765.1 - 0.00012 21.6 2.9 0.00012 21.6 2.9 4.8 4 0 0 4 4 4 2 PHD-finger WHIM1 PF15612.6 RLN10765.1 - 0.039 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 zf-PHD-like PF15446.6 RLN10765.1 - 0.97 9.0 30.7 0.47 10.1 3.4 4.4 3 1 1 4 4 4 0 PHD/FYVE-zinc-finger like domain SHNi-TPR PF10516.9 RLN10766.1 - 3.4e-11 42.4 0.1 7.9e-11 41.2 0.1 1.7 1 0 0 1 1 1 1 SHNi-TPR TPR_8 PF13181.6 RLN10766.1 - 0.00019 21.4 0.2 0.00095 19.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN10766.1 - 0.0023 18.2 5.0 0.088 13.1 0.5 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN10766.1 - 0.012 15.6 0.2 0.05 13.7 0.2 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN10766.1 - 0.024 14.5 0.2 0.073 12.9 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN10766.1 - 0.027 14.3 1.4 0.49 10.4 1.4 2.9 1 1 0 1 1 1 0 Tetratricopeptide repeat HEPN_Toprim_N PF18871.1 RLN10766.1 - 0.12 12.3 2.1 0.47 10.3 0.3 2.2 2 0 0 2 2 2 0 HEPN/Toprim N-terminal domain 1 MIF4G_like_2 PF09090.11 RLN10767.1 - 1.4e-27 96.8 0.0 5.9e-27 94.8 0.0 1.9 2 0 0 2 2 2 1 MIF4G like MIF4G_like PF09088.11 RLN10767.1 - 4.4e-27 95.1 0.2 9e-27 94.1 0.2 1.5 1 0 0 1 1 1 1 MIF4G like FSH1 PF03959.13 RLN10768.1 - 1.3e-34 119.7 0.0 1.6e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 RLN10768.1 - 0.00023 20.5 0.1 0.063 12.5 0.0 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN10768.1 - 0.0016 19.1 0.0 0.11 13.1 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 RLN10768.1 - 0.014 14.9 0.1 0.091 12.2 0.1 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 RLN10768.1 - 0.016 15.0 1.1 0.22 11.3 1.1 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 RLN10768.1 - 0.11 12.1 0.2 1.9 8.1 0.1 2.1 1 1 0 2 2 2 0 alpha/beta hydrolase fold AhpC-TSA PF00578.21 RLN10769.1 - 4.5e-35 120.3 0.0 6.3e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RLN10769.1 - 2.9e-13 49.8 0.0 3.8e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 RLN10769.1 - 4.9e-08 32.7 0.1 1e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 RLN10769.1 - 0.071 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 SCO1/SenC Glyco_transf_41 PF13844.6 RLN10770.1 - 7.3e-79 265.4 0.0 7e-46 156.6 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 RLN10770.1 - 8.5e-23 78.6 19.3 0.00011 22.0 0.5 10.9 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_17 PF13431.6 RLN10770.1 - 4.3e-19 67.4 7.9 0.0016 18.6 0.0 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 RLN10770.1 - 8e-19 68.0 29.3 5.4e-05 23.8 0.0 7.3 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 RLN10770.1 - 2.6e-18 64.6 0.2 0.0098 16.0 0.1 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 RLN10770.1 - 4.2e-16 59.2 27.4 0.00048 20.6 0.0 7.6 5 2 3 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN10770.1 - 2.6e-14 52.3 18.9 0.00017 21.3 0.3 10.3 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN10770.1 - 9.3e-14 51.0 39.8 0.0025 18.5 0.8 11.6 7 3 5 12 12 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 RLN10770.1 - 5.6e-12 45.2 15.4 0.023 14.4 0.0 8.3 6 2 3 9 9 9 5 TPR repeat TPR_12 PF13424.6 RLN10770.1 - 5.2e-11 42.7 35.5 0.00028 21.1 0.6 7.7 4 3 4 8 8 8 5 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN10770.1 - 4.4e-09 36.4 3.7 0.0036 17.5 0.0 4.2 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 RLN10770.1 - 1.2e-08 34.4 22.4 0.11 12.6 0.3 8.2 9 0 0 9 9 7 3 Tetratricopeptide repeat Glyco_trans_1_4 PF13692.6 RLN10770.1 - 3.8e-05 24.1 0.0 0.00021 21.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 TPR_9 PF13371.6 RLN10770.1 - 4.2e-05 23.6 18.9 0.0065 16.6 0.3 6.2 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 RLN10770.1 - 8.7e-05 22.9 12.3 2.9 8.7 0.1 8.6 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN10770.1 - 0.00023 20.9 39.1 0.052 13.4 1.0 8.8 10 0 0 10 10 8 3 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 RLN10770.1 - 0.0014 18.3 1.0 3 7.5 0.1 3.9 3 0 0 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) Glycos_transf_1 PF00534.20 RLN10770.1 - 0.0015 18.1 0.0 0.004 16.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 RLN10770.1 - 0.0019 18.2 0.3 1.3 9.0 0.0 3.9 3 1 0 3 3 3 1 Glycosyltransferase Family 4 NARP1 PF12569.8 RLN10770.1 - 0.0037 16.2 10.7 0.31 9.9 0.4 4.7 3 2 2 5 5 5 1 NMDA receptor-regulated protein 1 TPPII_N PF12583.8 RLN10770.1 - 0.052 14.1 0.2 1.6 9.3 0.1 2.6 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal Glyco_trans_4_3 PF12000.8 RLN10770.1 - 0.068 12.9 0.0 0.29 10.8 0.0 2.2 1 0 0 1 1 1 0 Glycosyl transferase family 4 group PPR PF01535.20 RLN10770.1 - 0.22 11.9 0.2 17 5.9 0.0 3.0 2 0 0 2 2 2 0 PPR repeat TPR_20 PF14561.6 RLN10770.1 - 0.32 11.4 16.1 2.7 8.4 0.1 6.8 5 3 3 8 8 8 0 Tetratricopeptide repeat DUF4810 PF16068.5 RLN10770.1 - 0.88 10.2 3.6 2.5 8.7 0.3 3.4 3 2 1 4 4 3 0 Domain of unknown function (DUF4810) TPR_3 PF07720.12 RLN10770.1 - 1.9 8.6 5.2 6.5 6.9 0.0 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat BTAD PF03704.17 RLN10770.1 - 7.8 6.9 18.3 0.025 15.0 3.1 4.1 5 0 0 5 5 3 0 Bacterial transcriptional activator domain FSH1 PF03959.13 RLN10771.1 - 3.6e-39 134.6 0.0 2e-33 115.9 0.0 2.0 1 1 1 2 2 2 2 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 RLN10771.1 - 0.025 13.8 0.1 0.28 10.4 0.0 2.1 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Palm_thioest PF02089.15 RLN10771.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_2 PF02230.16 RLN10771.1 - 0.42 10.4 1.5 4.2 7.1 1.1 2.3 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase LHC PF00556.20 RLN10772.1 - 0.012 15.8 0.2 0.018 15.2 0.2 1.2 1 0 0 1 1 1 0 Antenna complex alpha/beta subunit COX7C PF02935.16 RLN10772.1 - 0.23 11.7 2.3 1.5 9.1 2.3 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIIc CNOT1_HEAT PF16418.5 RLN10787.1 - 0.0033 17.5 0.0 0.013 15.6 0.0 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat CppA_C PF14507.6 RLN10787.1 - 0.1 13.3 0.1 0.4 11.4 0.0 2.0 2 0 0 2 2 2 0 CppA C-terminal Piwi PF02171.17 RLN10788.1 - 5.4e-89 298.4 0.0 7e-89 298.0 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 RLN10788.1 - 9.4e-12 45.0 0.1 7.3e-11 42.2 0.0 2.3 2 0 0 2 2 2 1 Mid domain of argonaute ArgoL2 PF16488.5 RLN10788.1 - 2.5e-10 40.6 0.0 5.2e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain LPD18 PF18832.1 RLN10788.1 - 0.18 11.9 0.0 2.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 18 MULE PF10551.9 RLN10810.1 - 2.5e-12 47.0 0.1 7e-12 45.6 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 RLN10810.1 - 0.021 15.5 0.1 0.051 14.3 0.1 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain B56 PF01603.20 RLN10820.1 - 2.6e-145 484.5 6.4 4.2e-140 467.4 0.6 2.0 1 1 1 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Ribosomal_S18 PF01084.20 RLN10821.1 - 3.1e-18 65.7 0.6 4.5e-18 65.2 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 Astro_capsid_p PF12226.8 RLN10821.1 - 0.016 14.4 1.2 0.016 14.4 1.2 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF4611 PF15387.6 RLN10821.1 - 0.093 13.0 2.5 0.15 12.3 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) YL1 PF05764.13 RLN10821.1 - 0.98 9.5 5.5 1.3 9.1 5.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein FRQ PF09421.10 RLN10822.1 - 0.085 10.9 3.6 0.1 10.6 3.6 1.2 1 0 0 1 1 1 0 Frequency clock protein DUF4044 PF13253.6 RLN10822.1 - 0.15 11.6 0.7 0.25 10.9 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) BUD22 PF09073.10 RLN10822.1 - 5.4 6.2 15.5 6.7 5.9 15.5 1.1 1 0 0 1 1 1 0 BUD22 DASH_Duo1 PF08651.10 RLN10825.1 - 0.028 14.2 0.7 0.049 13.4 0.7 1.4 1 0 0 1 1 1 0 DASH complex subunit Duo1 AAA_28 PF13521.6 RLN10838.1 - 1.9e-05 25.0 0.2 3.5e-05 24.1 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RLN10838.1 - 5.2e-05 23.8 0.0 0.00016 22.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 RLN10838.1 - 0.0023 18.1 0.0 0.0092 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain SNF5 PF04855.12 RLN10838.1 - 0.082 12.7 2.9 0.1 12.4 2.3 1.4 1 1 0 1 1 1 0 SNF5 / SMARCB1 / INI1 IMUP PF15761.5 RLN10838.1 - 0.55 11.0 4.8 0.92 10.2 4.8 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein TatD_DNase PF01026.21 RLN10839.1 - 4.3e-58 196.7 0.0 5.1e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 RLN10839.1 - 0.0031 17.3 0.0 0.0055 16.5 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase HTH_28 PF13518.6 RLN10841.1 - 0.00043 20.3 0.3 0.031 14.4 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 RLN10841.1 - 0.024 14.4 0.1 1 9.2 0.1 2.5 2 0 0 2 2 2 0 Homeodomain-like domain UQ_con PF00179.26 RLN10843.1 - 6.5e-41 139.3 0.1 2.2e-40 137.6 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 RLN10843.1 - 0.035 14.4 0.1 0.057 13.7 0.1 1.5 1 1 0 1 1 1 0 RWD domain TFIIB PF00382.19 RLN10844.1 - 3.7e-24 84.6 0.6 2.3e-11 43.6 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat NAD_binding_4 PF07993.12 RLN10844.1 - 0.074 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein HTH_23 PF13384.6 RLN10845.1 - 0.00085 19.0 0.1 1.6 8.6 0.0 2.9 3 0 0 3 3 3 2 Homeodomain-like domain HTH_IclR PF09339.10 RLN10845.1 - 0.0052 16.6 1.3 0.077 12.8 0.2 2.4 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_30 PF13556.6 RLN10845.1 - 0.02 14.7 1.9 0.35 10.7 0.6 2.6 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 RLN10845.1 - 0.024 14.7 0.1 6.7 6.9 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 RLN10845.1 - 0.028 14.7 0.2 0.083 13.1 0.2 1.8 1 0 0 1 1 1 0 Transposase Arm PF00514.23 RLN10847.1 - 6.1e-07 29.3 11.4 0.47 10.6 0.2 6.6 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 RLN10847.1 - 0.00013 21.9 4.8 1.5 8.9 0.1 4.5 2 2 2 4 4 4 2 Spinocerebellar ataxia type 10 protein domain CDC14 PF08045.11 RLN10847.1 - 0.036 13.2 1.1 0.23 10.6 0.1 2.6 2 1 1 3 3 3 0 Cell division control protein 14, SIN component DUF4704 PF15787.5 RLN10847.1 - 0.16 11.2 3.2 0.15 11.3 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4704) DUF3361 PF11841.8 RLN10847.1 - 0.27 11.2 7.3 0.43 10.5 0.5 3.2 2 2 2 4 4 4 0 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 RLN10847.1 - 0.53 10.4 3.2 9.7 6.3 0.3 3.1 3 1 0 3 3 3 0 V-ATPase subunit H DPM3 PF08285.11 RLN10848.1 - 3.6e-27 94.4 1.9 4e-27 94.2 1.9 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Phage_holin_3_6 PF07332.11 RLN10848.1 - 0.047 13.7 1.9 0.064 13.3 1.9 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Solute_trans_a PF03619.16 RLN10848.1 - 0.059 12.9 0.5 0.075 12.5 0.5 1.0 1 0 0 1 1 1 0 Organic solute transporter Ostalpha FYVE PF01363.21 RLN10855.1 - 5.8e-17 61.6 4.9 5.8e-17 61.6 4.9 2.4 2 1 0 2 2 2 1 FYVE zinc finger PI3Ka PF00613.20 RLN10855.1 - 3.2e-09 36.4 0.2 3.1e-05 23.5 0.1 2.3 2 0 0 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 RLN10855.1 - 0.00026 20.9 0.0 0.00046 20.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase F-box-like PF12937.7 RLN10855.1 - 0.022 14.7 0.2 0.06 13.2 0.2 1.8 1 0 0 1 1 1 0 F-box-like Elf1 PF05129.13 RLN10855.1 - 0.074 13.1 1.1 0.19 11.8 1.1 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like FXR_C1 PF16096.5 RLN10855.1 - 6.4 7.1 9.1 0.91 9.8 0.4 2.9 3 0 0 3 3 3 0 Fragile X-related 1 protein C-terminal region 2 MRI PF15325.6 RLN10855.1 - 6.5 7.9 5.8 2.6 9.2 0.1 3.0 3 1 0 3 3 3 0 Modulator of retrovirus infection TB2_DP1_HVA22 PF03134.19 RLN10856.1 - 9.9e-31 105.5 6.6 1.5e-30 105.0 6.6 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Dimeth_Pyl PF09505.10 RLN10857.1 - 0.041 12.4 0.0 0.059 11.9 0.0 1.1 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) Cullin_binding PF03556.15 RLN10859.1 - 4.2e-30 104.7 0.1 6.3e-30 104.1 0.1 1.3 1 0 0 1 1 1 1 Cullin binding SAP PF02037.27 RLN10859.1 - 0.00063 19.4 0.1 0.0014 18.3 0.1 1.6 1 0 0 1 1 1 1 SAP domain Glyco_hydro_5_C PF18564.1 RLN10861.1 - 3.1e-18 66.1 0.7 5.9e-18 65.2 0.7 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 RLN10861.1 - 0.014 14.9 0.0 3.4 7.0 0.0 2.1 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 RLN10862.1 - 1.6e-19 70.2 0.2 3.5e-19 69.1 0.2 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain B12D PF06522.11 RLN10865.1 - 3.2e-20 71.7 0.0 4.6e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit LRR_4 PF12799.7 RLN10866.1 - 7.5e-15 54.8 10.6 0.005 17.2 0.0 5.8 2 1 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN10866.1 - 1.9e-13 50.3 0.1 9e-10 38.3 0.0 3.1 1 1 3 4 4 4 3 Leucine-rich repeat LRR_8 PF13855.6 RLN10866.1 - 2.8e-09 36.6 12.4 0.0031 17.2 0.2 5.4 2 2 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 RLN10866.1 - 2.2e-06 27.2 5.9 5.6 7.3 0.1 7.4 7 0 0 7 7 7 1 Leucine Rich repeat Ubiquitin_2 PF14560.6 RLN10866.1 - 0.0039 17.6 0.0 0.022 15.2 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-like domain CAP_GLY PF01302.25 RLN10866.1 - 0.0052 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_1 PF00560.33 RLN10866.1 - 0.0088 16.4 4.2 42 5.2 0.1 6.5 7 1 0 7 7 7 0 Leucine Rich Repeat BT1 PF03092.16 RLN10869.1 - 1.5e-11 43.2 15.7 5.6e-08 31.5 1.3 3.2 3 0 0 3 3 3 3 BT1 family ERGIC_N PF13850.6 RLN10869.1 - 0.42 11.0 4.7 11 6.4 0.0 3.6 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TBCC PF07986.12 RLN10873.1 - 3.7e-18 65.4 0.0 9.9e-10 38.2 0.0 2.6 2 0 0 2 2 2 2 Tubulin binding cofactor C DUF2614 PF11023.8 RLN10873.1 - 0.062 13.4 0.5 0.14 12.3 0.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain SURNod19 PF07712.12 RLN10874.1 - 7.4e-48 163.2 9.4 6.9e-46 156.7 9.4 3.2 1 1 0 1 1 1 1 Stress up-regulated Nod 19 zf-C5HC2 PF02928.16 RLN10874.1 - 7.4 7.0 10.5 0.094 13.1 2.4 2.0 2 0 0 2 2 2 0 C5HC2 zinc finger RRM_1 PF00076.22 RLN10875.1 - 2.2e-17 62.6 0.1 1.6e-06 27.9 0.0 4.4 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN10875.1 - 0.00016 21.7 0.0 1.2 9.3 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif SID-1_RNA_chan PF13965.6 RLN10875.1 - 5.2 5.3 8.8 7.4 4.8 8.8 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ABC2_membrane PF01061.24 RLN10876.1 - 5.2e-27 94.6 27.9 7.9e-27 94.0 27.9 1.3 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN10876.1 - 0.0045 16.9 0.1 0.0045 16.9 0.1 2.9 3 0 0 3 3 3 1 CDR ABC transporter LRR_8 PF13855.6 RLN10878.1 - 0.039 13.7 0.0 0.17 11.7 0.0 2.1 1 1 0 1 1 1 0 Leucine rich repeat Phage_holin_3_6 PF07332.11 RLN10878.1 - 0.14 12.2 2.6 0.38 10.8 2.6 1.7 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Defensin_int PF17858.1 RLN10900.1 - 0.45 10.6 3.3 6.6 6.8 0.0 3.8 4 0 0 4 4 4 0 Platypus intermediate defensin-like peptide Dickkopf_N PF04706.12 RLN10900.1 - 1.2 9.7 27.2 0.97 10.0 2.0 5.8 5 1 1 6 6 6 0 Dickkopf N-terminal cysteine-rich region Lig_chan PF00060.26 RLN10901.1 - 0.045 13.6 0.1 46 3.8 0.0 3.0 3 0 0 3 3 3 0 Ligand-gated ion channel PMP1_2 PF08114.11 RLN10901.1 - 0.096 12.5 9.5 6.1 6.7 0.3 3.4 3 0 0 3 3 3 0 ATPase proteolipid family DUF555 PF04475.12 RLN10901.1 - 0.33 11.3 1.2 27 5.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF555) AATase PF07247.12 RLN10902.1 - 0.2 10.2 0.0 0.3 9.6 0.0 1.2 1 0 0 1 1 1 0 Alcohol acetyltransferase RSN1_7TM PF02714.15 RLN10903.1 - 0.0002 20.8 7.9 0.056 12.8 7.6 3.1 1 1 1 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate Anoctamin PF04547.12 RLN10903.1 - 0.0023 16.8 4.4 0.0023 16.8 4.4 2.4 2 2 0 2 2 2 1 Calcium-activated chloride channel PalH PF08733.10 RLN10903.1 - 0.2 10.6 8.4 0.0077 15.3 1.9 1.9 2 0 0 2 2 2 0 PalH/RIM21 ubiquitin PF00240.23 RLN10904.1 - 1.5e-12 47.1 0.0 1.7e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 RLN10904.1 - 2e-05 25.1 0.0 2.2e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 RLN10904.1 - 0.0014 18.7 0.0 0.0018 18.3 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 RLN10904.1 - 0.04 13.7 0.0 0.052 13.4 0.0 1.3 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like IMPDH PF00478.25 RLN10906.1 - 6.3e-10 38.6 0.1 6.8e-10 38.5 0.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain PLDc_2 PF13091.6 RLN10907.1 - 3e-18 66.0 0.1 1.4e-10 41.2 0.0 3.4 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.22 RLN10907.1 - 1.3e-15 56.8 1.3 8.6e-08 32.1 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif HEAT PF02985.22 RLN10908.1 - 7.1e-32 106.7 32.5 0.0052 16.9 0.1 12.9 13 0 0 13 13 13 10 HEAT repeat HEAT_2 PF13646.6 RLN10908.1 - 8.4e-28 96.6 20.9 1.7e-09 37.9 0.0 7.6 4 1 3 7 7 7 6 HEAT repeats Vac14_Fab1_bd PF12755.7 RLN10908.1 - 2.2e-08 34.6 1.3 0.028 15.0 0.0 6.5 3 2 4 7 7 7 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 RLN10908.1 - 1.9e-07 31.2 8.5 8.8e-05 22.6 0.2 4.9 2 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 RLN10908.1 - 2.3e-07 31.2 24.4 0.022 15.3 0.6 8.4 3 3 6 9 9 9 4 HEAT-like repeat IFRD PF05004.13 RLN10908.1 - 0.00056 19.1 1.4 0.005 16.0 0.4 2.6 1 1 1 2 2 2 2 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 RLN10908.1 - 0.0016 17.1 9.0 0.011 14.3 2.5 3.8 1 1 2 3 3 3 2 Adaptin N terminal region DRIM PF07539.12 RLN10908.1 - 0.0063 14.9 0.6 0.026 12.8 0.7 1.9 2 0 0 2 2 2 1 Down-regulated in metastasis PH PF00169.29 RLN10909.1 - 3.6e-44 149.6 1.4 2.7e-15 56.8 0.0 3.4 3 0 0 3 3 3 3 PH domain PH_8 PF15409.6 RLN10909.1 - 5e-14 52.3 3.5 1.1e-06 28.9 0.1 3.8 3 1 0 3 3 3 3 Pleckstrin homology domain PH_11 PF15413.6 RLN10909.1 - 5.2e-09 36.5 17.3 0.00058 20.2 0.6 5.6 3 3 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.6 RLN10909.1 - 2.4e-06 27.6 1.0 0.052 13.7 0.0 3.4 4 0 0 4 4 4 2 PH domain PH_9 PF15410.6 RLN10909.1 - 0.00011 22.5 0.9 1.3 9.4 0.0 4.5 4 2 0 4 4 4 1 Pleckstrin homology domain PDZ_6 PF17820.1 RLN10909.1 - 0.091 12.6 0.2 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 PDZ domain PH_13 PF16652.5 RLN10909.1 - 0.12 12.2 0.0 18 5.1 0.0 2.8 3 0 0 3 3 3 0 Pleckstrin homology domain PH_4 PF15404.6 RLN10909.1 - 0.14 11.9 1.4 4.6 7.0 0.1 2.5 1 1 1 2 2 2 0 Pleckstrin homology domain KAR9 PF08580.10 RLN10909.1 - 8.2 4.8 9.7 13 4.2 9.7 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 zf-RING_2 PF13639.6 RLN10910.1 - 2e-12 47.3 8.6 2e-12 47.3 8.6 2.4 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN10910.1 - 9.4e-10 38.2 9.4 9.4e-10 38.2 9.4 2.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 RLN10910.1 - 2.4e-09 37.3 5.1 2.4e-09 37.3 5.1 3.2 3 0 0 3 3 3 1 zinc-ribbon zf-C3HC4 PF00097.25 RLN10910.1 - 4.5e-07 29.6 6.6 4.5e-07 29.6 6.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN10910.1 - 3.4e-06 27.2 12.6 3.4e-06 27.2 12.6 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 RLN10910.1 - 8.9e-06 25.3 6.4 2e-05 24.2 6.4 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 RLN10910.1 - 7.7e-05 22.6 8.0 0.0002 21.3 8.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 RLN10910.1 - 0.00037 20.5 4.4 0.00037 20.5 4.4 1.9 2 1 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RLN10910.1 - 0.00051 19.8 2.6 0.00051 19.8 2.6 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN10910.1 - 0.001 19.0 6.2 0.001 19.0 6.2 2.6 2 1 1 3 3 3 1 zinc-RING finger domain HypA PF01155.19 RLN10910.1 - 0.0085 16.1 6.8 0.2 11.7 2.3 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rad50_zn_hook PF04423.14 RLN10910.1 - 0.13 12.1 5.3 0.42 10.5 0.1 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-Nse PF11789.8 RLN10910.1 - 0.44 10.4 6.2 1 9.2 6.2 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FSA_C PF10479.9 RLN10910.1 - 0.61 8.2 4.9 0.77 7.8 4.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Elf1 PF05129.13 RLN10910.1 - 2.3 8.3 9.1 5.9 7.0 1.3 2.6 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like WD40 PF00400.32 RLN10913.1 - 8.8e-05 23.2 9.5 2.1 9.4 0.0 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat FlaC_arch PF05377.11 RLN10913.1 - 0.021 15.2 1.6 0.047 14.1 1.6 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) PD40 PF07676.12 RLN10913.1 - 0.044 13.8 0.0 0.2 11.6 0.0 2.2 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat NleF_casp_inhib PF16809.5 RLN10913.1 - 0.35 10.8 1.7 0.56 10.1 0.5 1.8 2 0 0 2 2 2 0 NleF caspase inhibitor Spc7 PF08317.11 RLN10913.1 - 0.4 9.5 6.6 0.64 8.8 6.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 RLN10913.1 - 1 9.9 10.7 2.3 8.7 10.7 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region UPF0242 PF06785.11 RLN10913.1 - 3.9 7.5 6.7 6.9 6.7 6.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TFIIA PF03153.13 RLN10913.1 - 6.3 6.7 18.4 9.9 6.0 18.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_25 PF13481.6 RLN10916.1 - 0.0047 16.5 0.2 0.012 15.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.7 RLN10916.1 - 0.012 14.6 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain RsgA_GTPase PF03193.16 RLN10916.1 - 0.041 13.8 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 RLN10916.1 - 0.048 13.7 0.0 0.43 10.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) PPV_E1_C PF00519.17 RLN10916.1 - 0.09 11.6 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase MeaB PF03308.16 RLN10916.1 - 0.1 11.5 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 RLN10916.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain BUD22 PF09073.10 RLN10998.1 - 0.03 13.7 20.5 0.039 13.3 20.5 1.1 1 0 0 1 1 1 0 BUD22 DUF4553 PF15090.6 RLN10998.1 - 0.074 12.0 4.8 0.098 11.6 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) SDA1 PF05285.12 RLN10998.1 - 0.25 10.7 24.7 0.33 10.3 24.7 1.1 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 RLN10998.1 - 0.27 9.6 24.4 0.34 9.3 24.4 1.0 1 0 0 1 1 1 0 Mpp10 protein Sec62 PF03839.16 RLN10998.1 - 0.31 10.5 8.6 0.46 10.0 8.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Nop14 PF04147.12 RLN10998.1 - 0.55 8.4 22.5 0.68 8.1 22.5 1.1 1 0 0 1 1 1 0 Nop14-like family Paramyxo_ncap PF00973.19 RLN10998.1 - 0.69 8.8 7.7 0.87 8.4 7.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CDC27 PF09507.10 RLN10998.1 - 0.98 8.7 20.8 1.2 8.4 20.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop53 PF07767.11 RLN10998.1 - 1.2 8.4 22.4 1.7 8.0 22.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Gti1_Pac2 PF09729.9 RLN10998.1 - 2.3 8.3 5.0 3.4 7.7 5.0 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family SURF2 PF05477.11 RLN10998.1 - 3.1 7.4 14.2 5.3 6.7 14.2 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF2457 PF10446.9 RLN10998.1 - 4.9 6.2 26.8 6.4 5.8 26.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 RLN10998.1 - 5.2 5.1 26.1 6.7 4.7 26.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Paf1 PF03985.13 RLN10998.1 - 5.7 5.8 21.2 8.3 5.3 21.2 1.2 1 0 0 1 1 1 0 Paf1 Astro_capsid_p PF12226.8 RLN10998.1 - 7.8 5.5 19.7 11 5.0 19.7 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 RLN10998.1 - 8.6 4.5 19.1 11 4.2 19.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase_Tyr PF07714.17 RLN10999.1 - 1.5e-22 80.1 0.0 1.9e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN10999.1 - 1.7e-15 57.1 0.0 2.3e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 RLN11000.1 - 0.0083 17.0 6.7 0.17 12.8 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat bZIP_2 PF07716.15 RLN11001.1 - 1.3 9.2 6.1 3 8.0 6.1 1.7 1 0 0 1 1 1 0 Basic region leucine zipper Methyltransf_16 PF10294.9 RLN11002.1 - 1.1e-21 77.3 0.0 2.2e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 RLN11002.1 - 2.6e-05 23.8 0.2 6.6e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 RLN11002.1 - 0.007 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN11002.1 - 0.041 14.6 0.6 0.33 11.7 0.1 2.8 3 1 0 3 3 3 0 Methyltransferase domain MTS PF05175.14 RLN11002.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 RLN11002.1 - 0.14 12.0 0.1 18 5.1 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain ELO PF01151.18 RLN11003.1 - 5.2e-41 140.8 15.1 6.1e-41 140.6 15.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CCSMST1 PF15013.6 RLN11003.1 - 0.11 12.7 1.7 3.2 8.0 0.1 2.4 1 1 1 2 2 2 0 CCSMST1 family Retrotran_gag_2 PF14223.6 RLN11004.1 - 7.7e-07 28.9 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type ANAPC10 PF03256.16 RLN11005.1 - 2.9e-65 219.4 0.1 3.5e-65 219.1 0.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) PITH PF06201.13 RLN11005.1 - 0.018 15.3 0.0 0.053 13.7 0.0 1.7 1 1 1 2 2 2 0 PITH domain HD PF01966.22 RLN11005.1 - 0.05 13.8 0.1 0.069 13.4 0.1 1.2 1 0 0 1 1 1 0 HD domain DASH_Hsk3 PF08227.11 RLN11006.1 - 0.037 14.4 0.3 0.06 13.7 0.3 1.2 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like FliD_N PF02465.18 RLN11006.1 - 0.053 14.2 0.1 0.064 14.0 0.1 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Pkinase PF00069.25 RLN11016.1 - 9.2e-08 31.8 0.0 1.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN11016.1 - 0.0039 16.5 0.2 0.0093 15.3 0.2 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Nop14 PF04147.12 RLN11016.1 - 1.2 7.2 5.9 1.5 6.9 5.9 1.1 1 0 0 1 1 1 0 Nop14-like family Ank_2 PF12796.7 RLN11017.1 - 1.1e-21 77.2 2.0 5.9e-11 42.8 0.1 3.9 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN11017.1 - 1.2e-15 57.6 5.5 8.6e-06 26.2 0.7 5.4 3 1 3 6 6 6 5 Ankyrin repeats (many copies) WW PF00397.26 RLN11017.1 - 8.2e-14 51.4 9.7 6.9e-07 29.3 1.3 2.7 2 0 0 2 2 2 2 WW domain Ank_5 PF13857.6 RLN11017.1 - 2.7e-11 43.5 3.6 0.09 13.1 0.1 5.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN11017.1 - 3.8e-10 39.1 10.2 0.21 12.3 0.1 6.4 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 RLN11017.1 - 1.5e-09 37.8 5.7 0.38 11.3 0.0 6.6 6 0 0 6 6 6 2 Ankyrin repeat AIF_C PF14721.6 RLN11018.1 - 1.6e-17 64.1 0.0 6.5e-08 33.0 0.0 2.2 1 1 1 2 2 2 2 Apoptosis-inducing factor, mitochondrion-associated, C-term MtN3_slv PF03083.16 RLN11020.1 - 1.7e-31 108.1 18.9 8.4e-24 83.4 1.8 2.7 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RLN11020.1 - 7.2 6.5 10.1 2.3 8.0 0.1 3.7 4 0 0 4 4 4 0 PQ loop repeat Ank_4 PF13637.6 RLN11021.1 - 1.4e-37 127.5 23.7 7.4e-05 23.2 0.0 11.7 7 2 3 11 11 11 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN11021.1 - 2e-34 118.0 29.1 1.8e-06 28.5 0.2 7.5 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN11021.1 - 9.7e-33 111.8 26.9 0.034 14.5 0.1 15.6 4 3 13 17 17 17 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN11021.1 - 6.3e-20 69.2 6.6 12 6.9 0.0 14.6 16 0 0 16 16 16 2 Ankyrin repeat Ank PF00023.30 RLN11021.1 - 1.9e-05 24.9 5.0 28 5.4 0.0 8.6 7 2 2 9 9 9 0 Ankyrin repeat DUF1843 PF08898.10 RLN11021.1 - 2.2e-05 24.9 15.4 1.4 9.5 0.0 9.5 11 1 0 11 11 11 1 Domain of unknown function (DUF1843) DUF5049 PF16468.5 RLN11021.1 - 0.0025 17.7 0.0 66 3.5 0.0 5.9 5 1 2 7 7 7 0 Domain of unknown function (DUF5049) DUF3322 PF11795.8 RLN11021.1 - 0.0028 17.7 3.0 21 5.0 0.0 5.4 2 2 4 6 6 6 1 Uncharacterized protein conserved in bacteria N-term (DUF3322) KIX_2 PF16987.5 RLN11022.1 - 5.4e-12 45.5 0.2 3.6e-11 42.9 0.1 2.3 2 0 0 2 2 2 1 KIX domain Ax_dynein_light PF10211.9 RLN11022.1 - 0.067 13.1 8.3 0.8 9.6 0.5 3.4 3 0 0 3 3 3 0 Axonemal dynein light chain ABC_tran_CTD PF16326.5 RLN11022.1 - 0.18 12.1 3.8 0.35 11.1 0.7 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain LZ3wCH PF18517.1 RLN11025.1 - 0.14 12.3 0.0 0.9 9.7 0.0 2.3 3 0 0 3 3 3 0 Leucine zipper with capping helix domain Aldo_ket_red PF00248.21 RLN11026.1 - 2.5e-67 227.2 0.0 3.4e-67 226.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF5575 PF17738.1 RLN11027.1 - 0.0095 15.0 0.1 0.016 14.2 0.1 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF5575) HTH_Tnp_Tc5 PF03221.16 RLN11028.1 - 4.3e-06 26.7 0.1 9e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain FPN1 PF06963.12 RLN11029.1 - 3.7e-72 243.2 11.0 6.1e-48 163.5 0.2 2.0 1 1 1 2 2 2 2 Ferroportin1 (FPN1) DDE_1 PF03184.19 RLN11030.1 - 1.1e-11 44.7 0.0 1.9e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DEAD PF00270.29 RLN11030.1 - 3.6e-08 33.4 0.0 7.8e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HTH_Tnp_Tc5 PF03221.16 RLN11030.1 - 2.6e-07 30.5 0.0 2.6e-06 27.4 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_Tnp_1 PF01527.20 RLN11030.1 - 0.00064 20.0 2.4 0.0011 19.3 0.2 2.4 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 RLN11030.1 - 0.0024 17.6 0.1 0.013 15.3 0.0 2.3 3 1 1 4 4 4 1 DDE superfamily endonuclease TFIIA PF03153.13 RLN11030.1 - 1.9 8.4 6.1 0.25 11.3 1.5 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RIO1 PF01163.22 RLN11031.1 - 4.4e-58 196.0 0.1 1e-57 194.8 0.1 1.7 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 RLN11031.1 - 3.8e-06 26.4 2.5 1.7e-05 24.3 2.5 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family OrfB_Zn_ribbon PF07282.11 RLN11031.1 - 5.2e-06 26.3 2.1 0.087 12.8 0.3 2.6 2 0 0 2 2 2 2 Putative transposase DNA-binding domain Pkinase_fungal PF17667.1 RLN11031.1 - 1.1e-05 24.4 0.7 2.5e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 RLN11031.1 - 5.3e-05 23.3 0.1 0.00019 21.4 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 RLN11031.1 - 0.001 18.5 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN11031.1 - 0.017 14.4 0.3 0.07 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase Choline_kinase PF01633.20 RLN11031.1 - 0.029 14.0 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase PX PF00787.24 RLN11032.1 - 1.4e-06 28.2 0.1 2.6e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 PX domain DUF2451 PF10474.9 RLN11033.1 - 2.2e-53 181.4 0.0 4.4e-53 180.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 RLN11033.1 - 0.00036 19.9 1.3 0.021 14.1 0.5 3.0 2 1 1 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex DUF4611 PF15387.6 RLN11033.1 - 0.095 12.9 4.4 2.5 8.4 3.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Pox_Ag35 PF03286.14 RLN11033.1 - 0.47 10.2 6.6 0.054 13.3 1.7 2.0 3 0 0 3 3 3 0 Pox virus Ag35 surface protein DUF4589 PF15252.6 RLN11033.1 - 2.4 8.1 9.3 6.6 6.7 9.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4589) CDC45 PF02724.14 RLN11136.1 - 3.3 5.9 11.9 0.12 10.7 2.3 2.2 2 1 0 2 2 2 0 CDC45-like protein WD40 PF00400.32 RLN11140.1 - 2.7e-17 62.8 24.9 4.9e-05 24.0 0.4 9.1 9 1 0 9 9 9 6 WD domain, G-beta repeat Myb_DNA-bind_4 PF13837.6 RLN11150.1 - 2.4e-05 24.7 0.1 6.8e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 RLN11150.1 - 0.015 15.3 2.0 0.024 14.7 0.4 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain FlgN PF05130.12 RLN11150.1 - 0.079 13.5 6.6 0.12 12.9 3.4 2.4 2 0 0 2 2 2 0 FlgN protein Myb_DNA-bind_3 PF12776.7 RLN11150.1 - 0.12 13.4 1.9 0.14 13.1 0.3 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain SseC PF04888.12 RLN11150.1 - 0.16 11.5 6.8 0.28 10.7 6.8 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Com_YlbF PF06133.11 RLN11150.1 - 0.88 10.2 5.3 1.3 9.7 2.0 2.5 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA LMBR1 PF04791.16 RLN11150.1 - 1.7 7.4 4.1 2.2 7.1 4.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF5137 PF17220.3 RLN11150.1 - 5.6 7.9 7.2 2.9 8.8 0.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF5137) AMP-binding PF00501.28 RLN11151.1 - 1e-69 235.2 0.0 1.4e-61 208.4 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 RLN11151.1 - 1.2e-14 55.0 0.2 3e-14 53.8 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FYVE PF01363.21 RLN11152.1 - 4.2e-15 55.6 11.3 1.3e-14 54.1 11.3 1.9 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN11152.1 - 0.65 10.2 12.8 0.051 13.8 6.6 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger CAP_N PF01213.19 RLN11152.1 - 0.98 8.8 4.4 2.3 7.6 0.9 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DAGAT PF03982.13 RLN11153.1 - 3e-22 78.9 0.0 4e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase GTP_EFTU PF00009.27 RLN11156.1 - 1.3e-58 197.8 0.0 2.2e-58 197.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 RLN11156.1 - 5.4e-13 48.8 0.0 1.3e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 RLN11156.1 - 3.3e-10 39.9 0.0 8.1e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 RLN11156.1 - 3.3e-07 30.6 0.2 1.7e-06 28.3 0.2 2.4 1 1 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 RLN11156.1 - 7.3e-06 25.8 0.0 2.4e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 RLN11156.1 - 0.02 15.0 0.1 0.095 12.8 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase GET2 PF08690.10 RLN11156.1 - 0.032 13.9 0.8 0.078 12.6 0.8 1.6 1 0 0 1 1 1 0 GET complex subunit GET2 CBM_1 PF00734.18 RLN11157.1 - 8.8e-05 22.4 4.6 8.8e-05 22.4 4.6 14.0 13 4 0 13 13 13 6 Fungal cellulose binding domain Mannosyl_trans3 PF11051.8 RLN11159.1 - 3e-27 95.7 0.0 5.6e-27 94.8 0.0 1.4 1 1 0 1 1 1 1 Mannosyltransferase putative TAtT PF16811.5 RLN11159.1 - 0.057 12.7 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 TRAP transporter T-component Mannosyl_trans3 PF11051.8 RLN11160.1 - 1.4e-109 365.7 0.0 8.3e-27 94.2 0.0 4.7 4 0 0 4 4 4 4 Mannosyltransferase putative Nucleotid_trans PF03407.16 RLN11160.1 - 0.056 13.4 11.9 8.6 6.3 0.3 4.4 4 0 0 4 4 4 0 Nucleotide-diphospho-sugar transferase BA14K PF07886.11 RLN11160.1 - 0.083 12.8 1.4 13 5.8 0.0 3.0 3 0 0 3 3 3 0 BA14K-like protein Plus-3 PF03126.18 RLN11161.1 - 1.8e-14 54.1 0.5 2.6e-13 50.4 0.0 2.7 2 0 0 2 2 2 1 Plus-3 domain Exo_endo_phos_2 PF14529.6 RLN11163.1 - 0.00015 21.6 0.0 0.00038 20.3 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RLN11163.1 - 0.0017 17.9 0.0 0.0044 16.6 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Erp_C PF06780.11 RLN11163.1 - 1.5 8.8 4.8 0.85 9.6 0.2 2.3 2 0 0 2 2 2 0 Erp protein C-terminus Dimer_Tnp_hAT PF05699.14 RLN11165.1 - 0.0061 16.3 0.0 0.034 13.9 0.0 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region ENOD93 PF03386.14 RLN11166.1 - 8e-05 22.4 1.3 8e-05 22.4 1.3 1.6 2 0 0 2 2 2 1 Early nodulin 93 ENOD93 protein HIG_1_N PF04588.13 RLN11166.1 - 0.00019 21.6 1.4 0.00019 21.6 1.4 2.0 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Wzy_C PF04932.15 RLN11166.1 - 0.054 13.1 0.0 0.099 12.3 0.0 1.4 1 1 0 1 1 1 0 O-Antigen ligase CDC50 PF03381.15 RLN11167.1 - 1.3e-61 208.6 0.0 1.6e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Dimer_Tnp_hAT PF05699.14 RLN11168.1 - 2.3e-05 24.1 0.1 7.1e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Utp12 PF04003.12 RLN11168.1 - 0.01 16.2 0.2 0.023 15.0 0.2 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family EF-hand_1 PF00036.32 RLN11169.1 - 1.2e-09 37.0 1.1 2.1e-05 23.8 0.9 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RLN11169.1 - 1.9e-09 37.8 0.2 7.3e-09 35.9 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN11169.1 - 1.7e-07 30.6 0.2 0.021 14.7 0.5 2.7 2 0 0 2 2 2 2 EF-hand domain ALMT PF11744.8 RLN11169.1 - 5.2e-05 22.3 8.4 0.0027 16.6 0.0 2.6 2 0 0 2 2 2 2 Aluminium activated malate transporter EF-hand_8 PF13833.6 RLN11169.1 - 0.00025 20.8 0.1 0.0009 19.0 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair ArAE_2 PF10334.9 RLN11169.1 - 0.0082 16.0 0.7 1.6 8.5 0.0 3.0 3 0 0 3 3 3 1 Aromatic acid exporter family member 2 SPARC_Ca_bdg PF10591.9 RLN11169.1 - 0.089 13.1 0.0 0.36 11.2 0.0 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region ArAE_2_N PF10337.9 RLN11169.1 - 0.58 9.1 6.6 1.8 7.5 6.6 2.0 1 1 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal EF-hand_1 PF00036.32 RLN11170.1 - 5.2e-15 53.8 3.7 4.6e-07 28.9 0.2 2.8 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 RLN11170.1 - 5e-12 46.1 0.9 6e-11 42.6 0.3 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN11170.1 - 1.3e-11 43.4 1.9 0.00019 21.1 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 RLN11170.1 - 6.4e-09 34.9 0.3 0.0039 16.6 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RLN11170.1 - 7.2e-06 25.8 3.2 0.018 14.9 0.2 3.0 3 0 0 3 3 3 2 EF-hand domain pair ArAE_2 PF10334.9 RLN11170.1 - 0.055 13.3 0.1 0.17 11.7 0.1 1.9 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 SPARC_Ca_bdg PF10591.9 RLN11170.1 - 0.064 13.6 0.0 0.22 11.9 0.0 1.9 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Prok_Ub PF14454.6 RLN11170.1 - 0.14 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic Ubiquitin FUSC_2 PF13515.6 RLN11170.1 - 2.7 8.1 26.8 1 9.5 13.4 2.9 2 1 0 2 2 2 0 Fusaric acid resistance protein-like HD-ZIP_N PF04618.12 RLN11172.1 - 0.0016 18.9 0.0 0.0037 17.7 0.0 1.5 1 0 0 1 1 1 1 HD-ZIP protein N terminus TMP_2 PF06791.13 RLN11172.1 - 0.06 13.0 0.2 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 Prophage tail length tape measure protein CDC37_N PF03234.14 RLN11174.1 - 0.38 11.7 2.5 0.49 11.3 1.3 1.7 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding DUF3051 PF11252.8 RLN11175.1 - 0.0033 17.2 0.0 0.0053 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3051) CDC37_N PF03234.14 RLN11175.1 - 0.014 16.3 0.7 0.053 14.4 0.0 2.1 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Glyco_trans_1_4 PF13692.6 RLN11176.1 - 0.094 13.2 0.1 0.24 11.8 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferases group 1 Hpt PF01627.23 RLN11176.1 - 0.096 13.0 0.2 0.21 11.8 0.2 1.6 1 0 0 1 1 1 0 Hpt domain HpaB PF03241.13 RLN11176.1 - 0.11 11.5 0.3 0.2 10.7 0.3 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Glycos_transf_1 PF00534.20 RLN11176.1 - 0.21 11.1 0.0 0.63 9.6 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferases group 1 Pkinase PF00069.25 RLN11177.1 - 2.6e-67 227.0 0.0 3.8e-67 226.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN11177.1 - 9.5e-33 113.6 0.0 1.3e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Str_synth PF03088.16 RLN11177.1 - 1e-14 54.4 0.0 2.5e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Strictosidine synthase SGL PF08450.12 RLN11177.1 - 3.8e-10 39.8 0.0 2.4e-09 37.2 0.0 2.2 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Kinase-like PF14531.6 RLN11177.1 - 0.00027 20.3 0.0 0.00045 19.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN11177.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arylesterase PF01731.20 RLN11177.1 - 0.018 15.3 0.0 0.084 13.1 0.0 2.1 1 1 1 2 2 2 0 Arylesterase Haspin_kinase PF12330.8 RLN11177.1 - 0.18 10.7 0.0 0.3 10.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Utp13 PF08625.11 RLN13696.1 - 0.0002 21.3 0.1 0.0002 21.3 0.1 1.1 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain RPN1_RPN2_N PF17781.1 RLN13696.1 - 0.0055 16.1 0.1 0.0059 16.0 0.1 1.0 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RSN1_7TM PF02714.15 RLN13697.1 - 6.6e-32 110.9 12.0 9.8e-32 110.3 12.0 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 RLN13697.1 - 8.3e-11 42.4 0.0 1.6e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 RLN13697.1 - 0.92 8.3 6.4 5.5 5.7 6.4 1.9 1 1 0 1 1 1 0 Calcium-activated chloride channel zf-CCCH PF00642.24 RLN13698.1 - 1e-18 66.8 16.8 3.6e-11 42.7 5.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RLN13698.1 - 1e-13 50.8 16.7 7.1e-07 29.1 6.4 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 RLN13698.1 - 2e-13 49.8 13.4 4.6e-08 32.7 3.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 RLN13698.1 - 6.1e-05 23.3 11.0 0.008 16.6 2.3 2.6 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 RLN13698.1 - 0.00042 21.0 10.6 0.043 14.5 1.1 2.3 1 1 1 2 2 2 2 Torus domain zf-CCHH PF10283.9 RLN13698.1 - 4.6 7.3 10.3 9.1 6.4 1.6 2.9 2 0 0 2 2 2 0 PBZ domain DCP2 PF05026.13 RLN13699.1 - 7.6e-27 93.5 3.8 1.3e-26 92.7 3.8 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 RLN13699.1 - 3.1e-15 56.4 0.0 5.5e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain PRP3 PF08572.10 RLN13700.1 - 4.5e-62 209.7 8.6 8.8e-62 208.7 8.6 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 RLN13700.1 - 1.1e-41 142.4 0.4 2.5e-41 141.2 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DUF4241 PF14025.6 RLN13701.1 - 0.039 14.2 0.0 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4241) HR1 PF02185.16 RLN13701.1 - 0.23 11.6 22.9 0.16 12.1 5.9 3.9 3 0 0 3 3 3 0 Hr1 repeat YIF1 PF03878.15 RLN13702.1 - 0.0018 17.9 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 YIF1 ASFV_J13L PF05568.11 RLN13734.1 - 2.1 8.0 9.5 4.1 7.1 9.5 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein eIF3_N PF09440.10 RLN13738.1 - 0.1 13.1 6.7 0.089 13.2 4.8 1.9 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain Spec3 PF15795.5 RLN13738.1 - 0.13 12.9 0.2 0.53 10.9 0.0 2.0 2 0 0 2 2 2 0 Ectodermal ciliogenesis protein Allexi_40kDa PF05549.11 RLN13738.1 - 0.65 9.5 2.8 1.6 8.2 1.9 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein Arm PF00514.23 RLN13739.1 - 2.3e-19 68.7 3.4 1.8e-05 24.6 0.0 6.5 7 1 0 7 7 7 5 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 RLN13739.1 - 2.6e-07 30.6 0.2 0.0024 17.9 0.1 3.8 1 1 3 4 4 4 2 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 RLN13739.1 - 0.00048 20.5 8.6 0.03 14.7 1.7 3.8 1 1 4 5 5 5 3 HEAT repeats HEAT_EZ PF13513.6 RLN13739.1 - 0.00066 20.1 6.3 0.13 12.8 1.0 5.3 4 2 2 6 6 6 1 HEAT-like repeat HEAT_PBS PF03130.16 RLN13739.1 - 0.0012 19.3 9.3 23 6.0 0.1 6.4 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat UNC45-central PF11701.8 RLN13739.1 - 0.16 11.9 0.0 5.5 6.9 0.0 3.0 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central Sugar_tr PF00083.24 RLN13741.1 - 3.2e-39 135.1 5.1 4.1e-39 134.7 5.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN13741.1 - 9.9e-16 57.6 12.8 1.3e-15 57.2 12.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 RLN13741.1 - 8.8e-05 21.1 5.6 0.00011 20.7 5.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 RLN13741.1 - 0.002 17.1 0.4 0.0028 16.7 0.4 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_4 PF06779.14 RLN13741.1 - 0.0024 17.2 7.1 0.0033 16.8 7.1 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 RLN13742.1 - 9.9e-88 295.0 18.3 1.2e-87 294.7 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN13742.1 - 3.7e-27 95.2 29.8 5.9e-23 81.3 22.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 RLN13742.1 - 0.0032 16.0 6.5 0.0032 16.0 6.5 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) GWT1 PF06423.12 RLN13742.1 - 0.094 12.8 0.1 0.094 12.8 0.1 2.4 3 0 0 3 3 3 0 GWT1 Sugar_tr PF00083.24 RLN13743.1 - 5.2e-37 127.8 19.7 4.8e-36 124.6 19.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN13743.1 - 2e-35 122.3 35.5 2.2e-30 105.8 25.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily 7tm_3 PF00003.22 RLN13744.1 - 5.4e-38 131.0 31.8 5.4e-38 131.0 31.8 3.7 2 2 2 4 4 4 1 7 transmembrane sweet-taste receptor of 3 GCPR Sugar_tr PF00083.24 RLN13744.1 - 5.9e-23 81.4 23.0 5.9e-23 81.4 23.0 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN13744.1 - 2.4e-13 49.7 40.7 2.4e-13 49.7 40.7 3.4 1 1 0 2 2 2 1 Major Facilitator Superfamily Hist_deacetyl PF00850.19 RLN13745.1 - 3.1e-66 223.9 0.0 7e-66 222.8 0.0 1.7 1 0 0 1 1 1 1 Histone deacetylase domain HMA PF00403.26 RLN13745.1 - 0.87 10.1 4.0 0.85 10.1 1.6 2.3 2 0 0 2 2 2 0 Heavy-metal-associated domain ABC2_membrane PF01061.24 RLN13747.1 - 3.2e-36 124.7 24.6 4.7e-36 124.2 24.6 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN13747.1 - 9.1e-17 61.9 0.0 1.3e-16 61.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN13747.1 - 4.6e-05 23.4 0.3 0.061 13.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system PDR_CDR PF06422.12 RLN13747.1 - 0.00014 21.7 0.0 0.00014 21.7 0.0 2.1 2 0 0 2 2 1 1 CDR ABC transporter AAA_25 PF13481.6 RLN13747.1 - 0.00023 20.8 0.0 0.00038 20.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 RLN13747.1 - 0.0043 17.0 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN13747.1 - 0.0047 16.6 0.7 0.012 15.4 0.7 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 RLN13747.1 - 0.0088 15.5 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RLN13747.1 - 0.019 15.5 0.0 0.032 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 RLN13747.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF3382 PF11862.8 RLN13747.1 - 7.6 6.9 9.1 1.7 9.0 1.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) ABC2_membrane PF01061.24 RLN13748.1 - 7e-66 221.6 68.7 1.1e-36 126.3 24.5 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN13748.1 - 4.4e-17 62.9 0.0 6.8e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN13748.1 - 7.2e-05 22.7 0.0 0.082 12.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 RLN13748.1 - 0.00031 20.0 37.6 0.0017 17.5 10.8 2.9 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.6 RLN13748.1 - 0.0042 16.8 0.9 0.01 15.6 0.9 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain PDR_CDR PF06422.12 RLN13748.1 - 0.0086 16.0 0.1 0.0086 16.0 0.1 3.8 5 0 0 5 5 4 2 CDR ABC transporter RsgA_GTPase PF03193.16 RLN13748.1 - 0.0097 15.8 0.4 0.018 14.9 0.4 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 RLN13748.1 - 0.021 14.4 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PDR_assoc PF08370.11 RLN13748.1 - 0.033 13.9 0.1 0.033 13.9 0.1 3.8 4 0 0 4 4 3 0 Plant PDR ABC transporter associated SMC_N PF02463.19 RLN13748.1 - 0.1 12.1 1.0 0.27 10.6 0.2 2.1 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RLN13748.1 - 0.15 12.5 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 RLN13749.1 - 1.5e-66 223.8 68.0 3.5e-36 124.6 24.1 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN13749.1 - 5.4e-33 114.4 0.0 2.3e-15 57.3 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN13749.1 - 9.7e-07 28.9 0.0 0.17 11.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system PDR_CDR PF06422.12 RLN13749.1 - 1.1e-06 28.5 2.2 0.00037 20.3 0.0 3.2 2 0 0 2 2 2 1 CDR ABC transporter RsgA_GTPase PF03193.16 RLN13749.1 - 2.7e-06 27.4 1.6 0.011 15.7 0.2 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 RLN13749.1 - 1.9e-05 24.3 0.0 0.056 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 RLN13749.1 - 3e-05 24.5 0.1 0.31 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 RLN13749.1 - 3.5e-05 23.5 6.1 0.015 15.0 1.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN13749.1 - 0.00056 20.2 0.4 0.64 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 RLN13749.1 - 0.00087 18.8 2.9 0.6 9.5 0.2 3.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 RLN13749.1 - 0.0015 17.8 1.3 0.17 11.1 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin ABC2_membrane_3 PF12698.7 RLN13749.1 - 0.002 17.3 53.0 0.0083 15.3 17.0 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_30 PF13604.6 RLN13749.1 - 0.0036 17.1 1.0 1.3 8.7 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 RLN13749.1 - 0.0041 17.3 0.3 4.1 7.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.6 RLN13749.1 - 0.0041 17.7 0.4 0.28 11.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RLN13749.1 - 0.0059 17.2 0.0 6.8 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 RLN13749.1 - 0.0091 16.1 1.3 1.5 8.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 RLN13749.1 - 0.013 15.9 0.6 6.5 7.2 0.3 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 RLN13749.1 - 0.024 14.4 0.6 6.8 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 RLN13749.1 - 0.041 13.0 0.0 0.2 10.8 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit PRK PF00485.18 RLN13749.1 - 0.05 13.3 0.1 10 5.8 0.1 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 RLN13749.1 - 0.062 13.7 0.7 6.8 7.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Ploopntkinase3 PF18751.1 RLN13749.1 - 0.085 12.8 0.5 0.99 9.3 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_5 PF07728.14 RLN13749.1 - 0.11 12.5 0.5 3.6 7.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 RLN13749.1 - 0.12 12.5 5.2 0.94 9.5 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain cobW PF02492.19 RLN13749.1 - 0.13 11.9 1.5 1.4 8.4 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 RLN13749.1 - 0.15 12.0 4.3 9.6 6.1 1.1 2.7 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.17 RLN13749.1 - 0.22 11.3 0.6 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Roc PF08477.13 RLN13749.1 - 0.24 11.6 2.2 9.5 6.5 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 RLN13749.1 - 0.37 10.8 3.5 1.1 9.3 0.2 2.7 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 RLN13749.1 - 0.58 9.5 2.0 3.2 7.0 0.2 2.9 4 0 0 4 4 4 0 FtsK/SpoIIIE family ATPase PF06745.13 RLN13749.1 - 0.6 9.4 1.9 9.1 5.6 0.1 2.4 2 0 0 2 2 2 0 KaiC IPPT PF01715.17 RLN13753.1 - 1.3e-68 231.2 0.1 2.4e-68 230.4 0.0 1.4 2 0 0 2 2 2 1 IPP transferase DUF3449 PF11931.8 RLN13753.1 - 1e-07 31.9 0.2 2.1e-07 30.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) AAA_33 PF13671.6 RLN13753.1 - 1.8e-06 28.2 2.4 7.4e-06 26.2 0.5 2.8 2 1 0 2 2 2 1 AAA domain IPT PF01745.16 RLN13753.1 - 1.5e-05 24.5 0.1 3.4e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Isopentenyl transferase zf-met PF12874.7 RLN13753.1 - 2e-05 24.8 0.2 4.1e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RLN13753.1 - 3.9e-05 23.8 0.9 8.2e-05 22.8 0.9 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_18 PF13238.6 RLN13753.1 - 0.0015 19.1 0.8 0.26 11.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain zf-C2H2_2 PF12756.7 RLN13753.1 - 0.0034 17.7 0.3 0.015 15.6 0.2 2.0 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) NACHT PF05729.12 RLN13753.1 - 0.013 15.4 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 RLN13753.1 - 0.066 13.2 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE zf-C2H2_4 PF13894.6 RLN13753.1 - 0.069 14.0 0.3 1.1 10.3 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger AAA_28 PF13521.6 RLN13753.1 - 0.12 12.6 0.8 0.5 10.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain Ribosomal_L7Ae PF01248.26 RLN13754.1 - 6.6e-07 29.0 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3405 PF11885.8 RLN13754.1 - 0.15 10.7 0.1 0.23 10.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) DEAD PF00270.29 RLN13755.1 - 2.1e-37 128.5 0.0 5.9e-37 127.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN13755.1 - 6e-19 68.4 0.0 1.3e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN13755.1 - 5.4e-09 36.3 0.0 1.2e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RLN13755.1 - 0.11 12.8 1.6 15 5.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain Longin PF13774.6 RLN13756.1 - 2.4e-08 33.9 0.0 3.8e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain SAM_1 PF00536.30 RLN13757.1 - 6.9e-12 45.6 0.1 1.7e-11 44.4 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RLN13757.1 - 1.2e-10 41.3 0.0 2.4e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank PF00023.30 RLN13757.1 - 3.2e-08 33.7 0.2 1.5e-06 28.3 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 RLN13757.1 - 1e-07 32.1 0.1 1.2e-05 25.5 0.0 3.1 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN13757.1 - 2.9e-07 31.0 0.0 9.4e-06 26.1 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN13757.1 - 1.8e-06 27.8 0.0 6.8e-06 26.0 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 RLN13757.1 - 1.7e-05 25.3 0.1 0.00013 22.4 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) LBR_tudor PF09465.10 RLN13758.1 - 0.00048 19.9 0.0 0.00082 19.1 0.0 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Lsm_C PF14894.6 RLN13758.1 - 0.041 13.7 0.6 0.073 12.9 0.6 1.4 1 0 0 1 1 1 0 Lsm C-terminal Tudor_3 PF18115.1 RLN13758.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 RLN13758.1 - 0.059 13.4 0.1 0.14 12.1 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4537) ubiquitin PF00240.23 RLN13759.1 - 2.3e-18 65.7 0.0 6.5e-18 64.2 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 RLN13759.1 - 0.002 18.5 0.0 0.0066 16.9 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 RLN13759.1 - 0.0031 17.3 0.0 0.0067 16.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 RLN13759.1 - 0.15 12.1 0.4 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Borrelia_P83 PF05262.11 RLN13759.1 - 0.28 9.6 5.5 0.48 8.9 5.5 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3464 PF11947.8 RLN13759.1 - 1.3 8.8 4.6 6.7 6.5 1.4 2.5 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Presenilin PF01080.17 RLN13759.1 - 1.3 7.8 8.5 3 6.5 8.5 1.6 1 0 0 1 1 1 0 Presenilin FAM183 PF14886.6 RLN13760.1 - 5e-06 27.2 3.1 0.00018 22.2 3.1 2.9 1 1 0 1 1 1 1 FAM183A and FAM183B related Rhodanese PF00581.20 RLN13760.1 - 0.0084 16.6 0.0 0.19 12.2 0.0 2.6 1 1 0 1 1 1 1 Rhodanese-like domain MFS_5 PF05631.14 RLN13761.1 - 5.6e-30 104.4 0.3 6.6e-30 104.2 0.3 1.0 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 RLN13761.1 - 3.5e-05 22.9 6.4 4.4e-05 22.6 6.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Radial_spoke_3 PF06098.11 RLN13763.1 - 1e-40 139.8 7.0 1.4e-40 139.4 7.0 1.1 1 0 0 1 1 1 1 Radial spoke protein 3 GRDP-like PF07173.12 RLN13763.1 - 0.16 12.6 1.7 0.28 11.8 1.7 1.3 1 0 0 1 1 1 0 Glycine-rich domain-containing protein-like RRP36 PF06102.12 RLN13763.1 - 0.23 11.4 12.5 0.43 10.5 12.5 1.4 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Sugar_tr PF00083.24 RLN13766.1 - 4.6e-97 325.7 18.7 5.5e-97 325.5 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN13766.1 - 3.4e-28 98.6 29.8 2.8e-23 82.4 26.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CytB6-F_Fe-S PF08802.10 RLN13766.1 - 0.7 10.0 8.2 2.6 8.2 0.2 3.1 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit DUF2583 PF10762.9 RLN13766.1 - 1.2 9.6 8.7 1.1 9.7 4.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) RGS PF00615.19 RLN13767.1 - 2.2e-05 24.7 0.2 7.5e-05 23.0 0.2 1.9 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF4464 PF14713.6 RLN13768.1 - 1.9e-82 276.2 0.6 2.1e-82 276.0 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) Tropomyosin_1 PF12718.7 RLN13769.1 - 0.004 17.3 12.6 0.15 12.2 3.7 2.0 1 1 1 2 2 2 2 Tropomyosin like DUF1664 PF07889.12 RLN13769.1 - 0.0056 16.7 2.8 0.0058 16.7 1.3 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) Acyl-CoA_dh_2 PF08028.11 RLN13769.1 - 0.054 13.8 1.1 0.083 13.2 0.9 1.4 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain TMPIT PF07851.13 RLN13769.1 - 0.07 12.4 5.3 0.079 12.2 5.3 1.0 1 0 0 1 1 1 0 TMPIT-like protein MotA_ExbB PF01618.16 RLN13769.1 - 0.095 12.4 1.3 0.14 11.9 1.2 1.4 1 1 0 1 1 1 0 MotA/TolQ/ExbB proton channel family DUF5320 PF17253.2 RLN13769.1 - 0.32 12.1 2.2 0.39 11.8 1.5 1.4 1 1 1 2 2 2 0 Family of unknown function (DUF5320) ApoO PF09769.9 RLN13769.1 - 0.44 10.5 3.9 0.73 9.8 2.0 1.8 1 1 1 2 2 2 0 Apolipoprotein O Podoplanin PF05808.11 RLN13770.1 - 0.0055 16.8 4.0 0.0055 16.8 4.0 2.1 2 0 0 2 2 2 1 Podoplanin TMEM131_like PF12371.8 RLN13771.1 - 0.0012 19.1 0.0 0.0098 16.1 0.0 2.7 3 0 0 3 3 3 1 Transmembrane protein 131-like Ribosomal_S14 PF00253.21 RLN13772.1 - 2.3e-13 49.7 5.0 3e-13 49.3 5.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e STT3 PF02516.14 RLN13773.1 - 1.5e-47 162.7 10.7 1.8e-47 162.4 10.7 1.1 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 RLN13773.1 - 0.46 10.7 10.6 0.041 14.1 6.0 1.6 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Catalase PF00199.19 RLN13794.1 - 2.4e-189 629.3 0.0 3e-189 629.0 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 RLN13794.1 - 3.1e-20 72.1 0.2 8.8e-20 70.7 0.1 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive RNA_pol_3_Rpc31 PF11705.8 RLN13794.1 - 0.08 13.2 0.1 0.44 10.8 0.1 2.0 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Atu4866 PF11512.8 RLN13794.1 - 0.37 11.2 1.5 0.54 10.7 0.5 1.7 2 0 0 2 2 2 0 Agrobacterium tumefaciens protein Atu4866 Tannase PF07519.11 RLN13795.1 - 3.4e-13 49.3 0.1 3.8e-13 49.2 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase GFO_IDH_MocA PF01408.22 RLN13817.1 - 6.2e-07 30.3 0.0 1.1e-06 29.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 RLN13817.1 - 2.7e-05 24.1 0.0 4.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DapB_N PF01113.20 RLN13817.1 - 0.0079 16.3 0.0 0.13 12.4 0.0 2.3 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_N PF00044.24 RLN13817.1 - 0.013 15.9 0.0 0.052 13.9 0.0 2.0 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain EMC1_C PF07774.13 RLN13818.1 - 3.4e-19 69.4 0.0 5.6e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 RLN13818.1 - 1.9e-15 57.1 12.8 3.3e-12 46.5 3.3 3.8 4 0 0 4 4 4 2 PQQ-like domain DUF4987 PF16377.5 RLN13818.1 - 0.098 12.8 0.0 0.36 11.0 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function AAA_12 PF13087.6 RLN13819.1 - 1.4e-36 126.0 0.0 3.5e-36 124.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RLN13819.1 - 3.9e-19 69.5 1.9 4.4e-19 69.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RLN13819.1 - 1e-08 35.1 0.7 0.00015 21.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 RLN13819.1 - 1e-06 29.1 0.1 9e-06 26.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain zf-CCCH PF00642.24 RLN13819.1 - 6e-05 22.8 8.4 0.00015 21.6 8.4 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RLN13819.1 - 0.00062 19.7 9.1 0.0015 18.5 9.1 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 RLN13819.1 - 0.00097 18.9 5.9 0.0021 17.8 5.9 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger DUF2075 PF09848.9 RLN13819.1 - 0.0068 15.7 0.0 1.9 7.6 0.0 2.7 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) SesA PF17107.5 RLN13819.1 - 0.14 12.3 0.6 0.52 10.5 0.6 2.0 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases FYVE_2 PF02318.16 RLN13820.1 - 0.00017 21.7 6.8 0.00032 20.9 6.8 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger AAA_22 PF13401.6 RLN13838.1 - 0.0023 18.2 0.5 0.24 11.7 0.2 2.8 2 1 0 2 2 2 1 AAA domain ApbE PF02424.15 RLN13838.1 - 0.079 12.5 0.1 0.16 11.5 0.1 1.6 1 0 0 1 1 1 0 ApbE family Bac_DnaA PF00308.18 RLN13838.1 - 0.12 12.1 0.1 0.48 10.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial dnaA protein Pkinase PF00069.25 RLN13845.1 - 8e-50 169.6 0.0 2.4e-41 141.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN13845.1 - 3.5e-48 164.1 0.0 2.9e-40 138.2 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN13845.1 - 0.00017 20.5 0.2 0.00041 19.2 0.2 1.7 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN13845.1 - 0.0042 17.1 1.9 0.013 15.4 0.1 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 RLN13845.1 - 0.0074 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pox_A8 PF04745.12 RLN13845.1 - 0.17 10.9 0.1 0.26 10.3 0.1 1.2 1 0 0 1 1 1 0 VITF-3 subunit protein Phage_mat-A PF03863.13 RLN13846.1 - 0.077 11.9 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Phage maturation protein GlgX_C PF18390.1 RLN13846.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme C-terminal domain GBV-C_env PF12786.7 RLN13846.1 - 0.25 10.0 0.9 0.33 9.6 0.9 1.1 1 0 0 1 1 1 0 GB virus C genotype envelope Exo_endo_phos PF03372.23 RLN13849.1 - 2.4e-08 33.8 0.0 3e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Urb2 PF10441.9 RLN13849.1 - 0.011 15.7 0.6 0.016 15.2 0.6 1.3 1 0 0 1 1 1 0 Urb2/Npa2 family Pol_alpha_B_N PF08418.10 RLN13850.1 - 1.9e-06 28.0 0.0 2e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Pkinase PF00069.25 RLN13851.1 - 7.7e-64 215.6 0.0 1.2e-63 215.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN13851.1 - 2.5e-25 89.2 0.0 4.3e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN13851.1 - 7.3e-06 25.5 0.0 0.015 14.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like DUF2635 PF10948.8 RLN13851.1 - 0.0063 16.2 0.0 0.61 9.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2635) Kdo PF06293.14 RLN13851.1 - 0.015 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN13851.1 - 0.016 15.1 0.2 0.057 13.3 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family BTB_2 PF02214.22 RLN13861.1 - 1.3e-08 35.1 0.6 3.2e-08 33.8 0.2 1.7 2 0 0 2 2 2 1 BTB/POZ domain Toxin_YhaV PF11663.8 RLN13861.1 - 0.012 15.7 0.1 0.027 14.5 0.1 1.6 2 0 0 2 2 2 0 Toxin with endonuclease activity, of toxin-antitoxin system Abhydro_lipase PF04083.16 RLN13862.1 - 6e-17 61.0 0.0 1.1e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 RLN13862.1 - 5.7e-13 49.1 0.0 1.4e-12 47.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN13862.1 - 0.0005 19.4 0.0 0.0007 18.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 RNA_pol_Rpb5_N PF03871.14 RLN13862.1 - 0.078 13.6 0.1 0.5 11.0 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb5, N-terminal domain zf-rbx1 PF12678.7 RLN13863.1 - 2.2e-06 27.8 3.6 4.8e-06 26.8 3.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 RLN13863.1 - 6.5e-06 26.4 3.6 6.5e-06 26.4 3.6 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN13863.1 - 3.1e-05 23.7 3.2 7.4e-05 22.5 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN13863.1 - 0.00014 21.5 0.6 0.0005 19.8 0.6 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 RLN13863.1 - 0.00046 20.0 2.6 0.0011 18.8 2.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PTEN_C2 PF10409.9 RLN13863.1 - 0.017 14.9 0.0 0.056 13.2 0.0 1.7 2 0 0 2 2 2 0 C2 domain of PTEN tumour-suppressor protein CarbpepA_inh PF02977.15 RLN13863.1 - 0.098 12.5 3.7 0.27 11.1 3.7 1.7 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor zf-C3H2C3 PF17122.5 RLN13863.1 - 0.39 10.8 4.6 1.1 9.4 4.6 1.8 1 0 0 1 1 1 0 Zinc-finger zf-RING_5 PF14634.6 RLN13863.1 - 2.5 8.1 8.4 0.071 13.1 1.9 1.8 2 0 0 2 2 2 0 zinc-RING finger domain eIF3g PF12353.8 RLN13864.1 - 1.4e-32 112.7 1.5 2.1e-32 112.1 1.5 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 RLN13864.1 - 1.2e-19 69.8 0.0 2.2e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 RLN13864.1 - 0.023 14.9 1.6 10 6.3 0.0 3.1 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF445 PF04286.12 RLN13865.1 - 0.054 13.3 0.1 0.054 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) GIT_SHD PF08518.11 RLN13865.1 - 0.11 12.1 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT Sec15 PF04091.12 RLN13867.1 - 0.016 14.6 0.1 0.018 14.5 0.1 1.0 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like FYVE_2 PF02318.16 RLN13868.1 - 0.09 13.0 8.7 0.26 11.5 8.7 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4_2 PF13923.6 RLN13868.1 - 0.57 10.1 8.9 2.3 8.2 4.2 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN13868.1 - 1 9.2 10.3 1.1 9.2 4.4 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN13868.1 - 1.8 8.9 9.8 2.8 8.4 4.0 2.5 1 1 1 2 2 2 0 Ring finger domain Siva PF05458.12 RLN13868.1 - 2 8.1 12.9 6.9 6.3 12.8 1.9 1 1 0 1 1 1 0 Cd27 binding protein (Siva) Elicitin PF00964.17 RLN13872.1 - 2.6e-20 72.3 8.2 8.6e-11 41.8 0.8 2.4 2 0 0 2 2 2 2 Elicitin Elicitin PF00964.17 RLN13873.1 - 2e-06 27.8 0.1 3.2e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Elicitin Peroxin-3 PF04882.12 RLN13873.1 - 0.015 14.4 0.9 0.067 12.2 0.0 2.0 2 0 0 2 2 2 0 Peroxin-3 bZIP_1 PF00170.21 RLN13875.1 - 0.082 13.0 0.3 0.16 12.1 0.3 1.4 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 RLN13875.1 - 0.088 12.9 0.4 0.19 11.8 0.4 1.5 1 0 0 1 1 1 0 Basic region leucine zipper PGA2 PF07543.12 RLN13875.1 - 0.09 12.8 1.3 0.22 11.5 1.3 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 Ank_2 PF12796.7 RLN13876.1 - 1.2e-27 96.3 1.3 1.4e-07 32.0 0.0 6.2 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN13876.1 - 5.7e-26 90.6 1.1 4.3e-05 24.0 0.0 7.2 4 3 4 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN13876.1 - 1.9e-20 72.7 4.6 2.5e-06 27.7 0.0 5.8 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN13876.1 - 1.2e-15 56.0 2.4 0.025 15.1 0.1 7.6 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 RLN13876.1 - 1.3e-11 44.4 2.7 0.0018 18.6 0.1 5.5 5 0 0 5 5 5 2 Ankyrin repeat Fic PF02661.18 RLN13876.1 - 3e-11 44.1 0.0 8.6e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 Fic/DOC family bHLH-MYC_N PF14215.6 RLN13876.1 - 0.00016 22.0 0.0 0.00034 20.9 0.0 1.5 1 0 0 1 1 1 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal Glutaredoxin2_C PF04399.13 RLN13877.1 - 2.6e-45 153.5 0.0 3.1e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_N_3 PF13417.6 RLN13877.1 - 9.3e-09 35.6 0.0 2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN13877.1 - 8.8e-05 22.7 0.0 0.00016 21.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 RLN13877.1 - 0.00017 21.8 0.2 0.00035 20.7 0.2 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_N PF02798.20 RLN13877.1 - 0.032 14.6 0.0 0.12 12.8 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 RLN13877.1 - 0.11 13.3 0.0 0.33 11.7 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain TPR_1 PF00515.28 RLN13884.1 - 4.1e-13 48.5 9.2 0.0001 21.9 0.2 4.6 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN13884.1 - 4.4e-11 42.0 6.8 0.00045 20.1 0.1 4.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN13884.1 - 7e-10 38.4 1.0 0.0027 17.4 0.1 4.1 4 1 1 5 5 4 3 TPR repeat TPR_8 PF13181.6 RLN13884.1 - 6.9e-09 35.2 1.7 0.013 15.7 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN13884.1 - 3.8e-08 33.3 0.9 6e-05 23.0 0.1 3.4 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 RLN13884.1 - 1.8e-07 31.4 0.9 0.81 10.7 0.2 4.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 RLN13884.1 - 7.3e-06 26.2 3.0 0.0078 16.5 0.0 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN13884.1 - 0.00021 21.7 1.5 1.7 9.2 0.0 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN13884.1 - 0.00022 21.0 0.5 0.026 14.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN13884.1 - 0.00062 19.6 0.1 0.24 11.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN13884.1 - 0.0037 17.9 4.1 0.17 12.5 0.1 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN13884.1 - 0.0073 16.6 1.4 0.51 10.8 0.0 3.9 4 1 1 5 5 4 1 Tetratricopeptide repeat DUF3856 PF12968.7 RLN13884.1 - 0.015 15.4 2.8 0.49 10.5 0.1 2.8 2 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) BTAD PF03704.17 RLN13884.1 - 0.037 14.5 2.3 0.28 11.6 1.0 2.7 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 RLN13884.1 - 0.038 14.1 0.5 0.78 9.9 0.2 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN13884.1 - 0.046 14.4 1.7 39 5.2 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat ECH_2 PF16113.5 RLN13884.1 - 0.05 13.1 9.7 0.02 14.4 6.0 1.9 1 1 0 2 2 2 0 Enoyl-CoA hydratase/isomerase TOM20_plant PF06552.12 RLN13884.1 - 0.087 12.6 4.6 3.4 7.4 0.0 3.0 2 1 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 Pkinase PF00069.25 RLN13885.1 - 2.4e-25 89.4 0.0 3.2e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN13885.1 - 2.3e-12 46.8 0.0 3.1e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 RLN13885.1 - 0.023 15.4 0.4 0.023 15.4 0.4 2.9 2 2 0 2 2 2 0 Protein kinase C terminal domain PX PF00787.24 RLN13886.1 - 2.5e-15 56.4 0.0 7.9e-15 54.8 0.0 1.9 1 0 0 1 1 1 1 PX domain PH PF00169.29 RLN13886.1 - 6.5e-10 39.5 0.7 5.7e-06 26.8 0.4 3.4 4 0 0 4 4 4 2 PH domain DDHD PF02862.17 RLN13886.1 - 0.00014 22.1 0.1 0.00027 21.2 0.1 1.5 1 0 0 1 1 1 1 DDHD domain PH_11 PF15413.6 RLN13886.1 - 0.039 14.4 0.3 0.17 12.4 0.3 2.2 1 0 0 1 1 1 0 Pleckstrin homology domain PH_8 PF15409.6 RLN13886.1 - 0.14 12.5 0.0 1 9.7 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Glyco_hydro_3 PF00933.21 RLN13887.1 - 5.9e-50 170.5 0.0 7.7e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN13887.1 - 2.5e-37 128.8 0.0 4.1e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RLN13887.1 - 1.9e-14 53.5 0.1 4.5e-14 52.3 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Cullin_binding PF03556.15 RLN13888.1 - 3e-35 121.3 1.1 4.6e-35 120.7 1.1 1.3 1 0 0 1 1 1 1 Cullin binding IQ PF00612.27 RLN13889.1 - 2.8e-12 45.3 15.7 0.0018 17.9 0.3 4.9 4 0 0 4 4 4 4 IQ calmodulin-binding motif HRI1 PF16815.5 RLN13889.1 - 0.84 9.3 5.2 2.3 7.8 5.2 1.7 1 1 0 1 1 1 0 Protein HRI1 FYVE PF01363.21 RLN13890.1 - 0.044 13.9 0.9 0.25 11.5 0.9 2.1 1 1 0 1 1 1 0 FYVE zinc finger NYD-SP28_assoc PF14775.6 RLN13890.1 - 0.57 10.3 4.9 1.2 9.3 4.9 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain DUF155 PF02582.14 RLN13891.1 - 1.1e-43 149.3 0.2 3.2e-43 147.9 0.2 1.7 1 1 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 PH PF00169.29 RLN13901.1 - 3.9e-16 59.4 0.2 2.1e-10 41.0 0.0 2.8 2 1 0 2 2 2 2 PH domain PH_8 PF15409.6 RLN13901.1 - 4.9e-07 30.0 0.0 6.9e-06 26.3 0.0 2.6 3 0 0 3 3 3 1 Pleckstrin homology domain PH_11 PF15413.6 RLN13901.1 - 7.2e-06 26.4 2.4 0.0015 18.9 0.6 2.9 1 1 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.6 RLN13901.1 - 0.0044 17.3 0.4 0.013 15.8 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 RLN13901.1 - 0.0086 16.4 0.0 4.3 7.7 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain DUF3772 PF12607.8 RLN13902.1 - 0.047 13.4 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) DUF4214 PF13946.6 RLN13902.1 - 0.14 12.3 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) DUF3464 PF11947.8 RLN13902.1 - 0.46 10.2 3.1 0.21 11.3 0.8 1.6 1 1 1 2 2 2 0 Photosynthesis affected mutant 68 UPF0203 PF05254.12 RLN13903.1 - 1e-10 41.7 7.4 1e-10 41.7 7.4 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0203) LEA_4 PF02987.16 RLN13903.1 - 5.6e-05 23.1 26.5 0.0081 16.2 1.5 2.8 2 1 0 2 2 2 2 Late embryogenesis abundant protein Apolipoprotein PF01442.18 RLN13903.1 - 0.018 14.9 20.9 0.03 14.2 20.9 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain CX9C PF16860.5 RLN13903.1 - 0.058 13.4 5.0 0.28 11.2 0.9 2.4 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, YtxH PF12732.7 RLN13903.1 - 1.6 9.3 25.9 11 6.7 10.0 3.1 1 1 1 2 2 2 0 YtxH-like protein DUF1366 PF07104.11 RLN13903.1 - 1.8 8.3 10.2 0.087 12.5 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) DivIVA PF05103.13 RLN13903.1 - 2 8.5 27.0 0.069 13.2 11.2 2.2 1 1 1 2 2 2 0 DivIVA protein Exonuc_VII_L PF02601.15 RLN13903.1 - 2.1 7.9 13.3 2.7 7.5 13.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF883 PF05957.13 RLN13903.1 - 4.9 7.8 22.1 8.8 7.0 4.2 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) V_ATPase_I PF01496.19 RLN13903.1 - 5.3 4.8 14.6 6.3 4.6 14.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF445 PF04286.12 RLN13903.1 - 5.5 6.7 12.0 6.9 6.4 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Epimerase PF01370.21 RLN13904.1 - 1.8e-22 80.0 0.0 2.2e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RLN13904.1 - 0.00018 21.1 0.0 0.00021 20.8 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase AMP-binding PF00501.28 RLN13905.1 - 4.3e-71 239.7 0.0 7.7e-71 238.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 RLN13905.1 - 1.5e-59 201.9 0.0 1.6e-58 198.5 0.0 2.0 1 1 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 RLN13905.1 - 2e-05 25.4 0.0 5.9e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Citrate_synt PF00285.21 RLN13920.1 - 3.8e-103 345.3 0.0 5e-103 344.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain TIP49 PF06068.13 RLN13921.1 - 5.9e-99 331.6 0.6 9.4e-99 330.9 0.6 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 RLN13921.1 - 6.2e-26 90.3 0.6 1.5e-25 89.1 0.6 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA_22 PF13401.6 RLN13921.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Complex1_49kDa PF00346.19 RLN13921.1 - 0.045 12.8 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit CDC27 PF09507.10 RLN13922.1 - 3.4e-10 39.9 44.4 7e-10 38.9 41.7 2.0 2 0 0 2 2 2 1 DNA polymerase subunit Cdc27 S1_2 PF13509.6 RLN13922.1 - 0.12 12.4 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 S1 domain Gemini_C4 PF01492.17 RLN13922.1 - 0.54 10.2 3.4 0.47 10.4 0.8 2.2 2 0 0 2 2 2 0 Geminivirus C4 protein Pkinase_Tyr PF07714.17 RLN13923.1 - 1.7e-48 165.2 0.0 2.2e-44 151.7 0.0 3.6 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 RLN13923.1 - 3.8e-43 147.8 0.0 2.8e-38 131.8 0.0 3.8 5 0 0 5 5 5 2 Protein kinase domain PH PF00169.29 RLN13923.1 - 1.1e-15 58.0 2.9 6.9e-07 29.7 0.3 4.4 4 1 0 4 4 4 3 PH domain APH PF01636.23 RLN13923.1 - 0.013 15.5 0.5 0.054 13.4 0.1 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family PH_8 PF15409.6 RLN13923.1 - 0.03 14.6 0.2 0.16 12.3 0.2 2.4 1 0 0 1 1 1 0 Pleckstrin homology domain WASH-7_C PF14746.6 RLN13923.1 - 0.031 14.0 0.4 0.068 12.9 0.4 1.5 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal RIO1 PF01163.22 RLN13923.1 - 0.082 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 RLN13923.1 - 0.13 11.3 0.6 0.27 10.2 0.6 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 RLN13923.1 - 0.19 10.6 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain CENP-B_dimeris PF09026.10 RLN13923.1 - 3.7 8.0 8.1 36 4.8 7.1 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Fe-S_biosyn PF01521.20 RLN13924.1 - 6.3e-08 32.8 0.0 6.7e-08 32.7 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Porin_3 PF01459.22 RLN13926.1 - 3.9e-39 134.7 9.0 5.8e-39 134.2 9.0 1.2 1 0 0 1 1 1 1 Eukaryotic porin CS PF04969.16 RLN13926.1 - 5.6e-15 56.1 0.0 1.5e-14 54.7 0.0 1.8 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 RLN13926.1 - 4.8e-14 52.1 0.1 1.2e-13 50.8 0.1 1.7 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. Hid1 PF12722.7 RLN13926.1 - 0.2 9.7 3.0 0.29 9.2 3.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EF-hand_8 PF13833.6 RLN13928.1 - 2.1e-13 49.9 0.9 8.6e-12 44.7 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 RLN13928.1 - 1.2e-09 38.5 1.9 0.0014 19.1 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 RLN13928.1 - 5.6e-05 22.4 0.8 0.00067 19.0 0.2 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RLN13928.1 - 0.00033 20.4 1.1 1.1 9.4 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain FlgN PF05130.12 RLN13928.1 - 0.067 13.7 1.6 0.15 12.6 1.4 1.8 1 1 0 1 1 1 0 FlgN protein EF-hand_5 PF13202.6 RLN13928.1 - 0.073 12.6 0.1 0.32 10.6 0.1 2.1 1 0 0 1 1 1 0 EF hand Porin_3 PF01459.22 RLN13929.1 - 1e-39 136.7 14.4 1.1e-39 136.5 14.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin Adeno_E1B_19K PF01691.16 RLN13929.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen KH_6 PF15985.5 RLN13930.1 - 3.5e-14 52.9 0.1 8.2e-14 51.7 0.1 1.7 1 0 0 1 1 1 1 KH domain LSM PF01423.22 RLN13930.1 - 1.5e-05 24.5 0.1 3e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 LSM domain DUF1128 PF06569.11 RLN13930.1 - 0.028 14.4 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) SSXT PF05030.12 RLN13931.1 - 3.1e-18 65.2 2.3 3.1e-18 65.2 2.3 2.6 2 1 0 2 2 2 1 SSXT protein (N-terminal region) GREB1 PF15782.5 RLN13931.1 - 0.22 8.6 15.4 0.27 8.3 15.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ndc1_Nup PF09531.10 RLN13931.1 - 6.1 5.4 15.1 7.6 5.1 15.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LMBR1 PF04791.16 RLN13931.1 - 8.2 5.2 10.4 11 4.8 10.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Mitoc_mL59 PF18126.1 RLN13932.1 - 2.8e-11 43.8 3.3 6.2e-11 42.7 3.3 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 DUF1351 PF07083.11 RLN13932.1 - 0.036 13.9 0.2 0.048 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) RseA_N PF03872.13 RLN13932.1 - 0.043 14.3 0.0 0.082 13.4 0.0 1.5 2 0 0 2 2 2 0 Anti sigma-E protein RseA, N-terminal domain 5_nucleotid_C PF02872.18 RLN13941.1 - 3e-22 79.5 0.0 5.5e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 RLN13941.1 - 1.5e-08 35.4 0.0 2.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ATP-gua_Ptrans PF00217.19 RLN13942.1 - 6e-83 277.5 0.0 2.3e-70 236.4 0.0 2.1 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 RLN13942.1 - 9.4e-28 96.4 0.0 2.2e-27 95.2 0.0 1.7 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain His_Phos_2 PF00328.22 RLN13944.1 - 0.0003 20.3 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) EF-hand_7 PF13499.6 RLN13945.1 - 4.2e-06 27.1 0.7 4.5e-05 23.8 0.7 2.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN13945.1 - 2.2e-05 23.7 0.2 0.00045 19.6 0.0 2.7 2 0 0 2 2 2 1 EF hand C2 PF00168.30 RLN13945.1 - 2.9e-05 24.3 0.1 0.14 12.5 0.0 2.7 2 0 0 2 2 2 2 C2 domain EF-hand_6 PF13405.6 RLN13945.1 - 3.1e-05 23.6 0.4 0.0014 18.4 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 RLN13945.1 - 0.00018 20.8 0.8 0.0074 15.7 0.2 2.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 RLN13945.1 - 0.00019 21.2 0.6 0.12 12.2 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair Prominin PF05478.11 RLN13946.1 - 0.021 12.8 3.2 0.039 11.9 3.2 1.4 1 0 0 1 1 1 0 Prominin WD40 PF00400.32 RLN13946.1 - 0.15 13.0 0.5 47 5.1 0.0 4.3 5 0 0 5 5 5 0 WD domain, G-beta repeat NopRA1 PF16201.5 RLN13947.1 - 1.2e-48 165.4 0.4 1.2e-48 165.4 0.4 2.1 3 0 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 Autophagy_N PF03986.13 RLN13948.1 - 1.9e-20 73.2 0.1 3.7e-20 72.3 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 RLN13948.1 - 6.4e-19 68.3 0.3 2.4e-18 66.4 0.2 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 RLN13948.1 - 1.3e-14 53.3 3.0 2.5e-14 52.5 3.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Dynein_C PF18199.1 RLN13950.1 - 4.2e-87 292.2 0.1 4.9e-87 292.0 0.1 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 RLN13950.1 - 3e-13 49.9 0.0 5.3e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Voltage_CLC PF00654.20 RLN13960.1 - 1.2e-15 57.7 12.9 1.4e-15 57.4 12.9 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel DUF4018 PF13210.6 RLN13960.1 - 0.022 14.5 2.1 0.036 13.8 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) DUF3318 PF11780.8 RLN13964.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Ribosomal_L27e PF01777.18 RLN13965.1 - 5.6e-13 49.1 0.2 6.4e-13 48.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal L27e protein family FYVE PF01363.21 RLN13967.1 - 1.8e-05 24.8 13.0 0.00018 21.6 0.3 3.5 3 1 0 3 3 3 2 FYVE zinc finger zinc_ribbon_2 PF13240.6 RLN13967.1 - 0.78 9.5 11.2 1.1 9.1 0.7 3.2 3 0 0 3 3 3 0 zinc-ribbon domain UPF0547 PF10571.9 RLN13967.1 - 0.83 9.8 6.1 15 5.8 0.9 3.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Ribosomal_L32p PF01783.23 RLN13967.1 - 1.4 9.3 5.9 1.9 8.8 0.3 3.5 4 0 0 4 4 4 0 Ribosomal L32p protein family SBF PF01758.16 RLN13968.1 - 8.3e-44 149.6 3.9 8.3e-44 149.6 3.9 1.6 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF4330 PF14221.6 RLN13968.1 - 0.099 12.9 0.8 3.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) OST3_OST6 PF04756.13 RLN13969.1 - 2e-16 60.2 4.4 2.7e-14 53.2 3.6 2.2 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family DUF2516 PF10724.9 RLN13969.1 - 0.28 11.5 3.3 0.49 10.7 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2516) PGM_PMM_IV PF00408.20 RLN13970.1 - 3.7e-11 43.0 0.1 7.8e-11 42.0 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 RLN13970.1 - 4.1e-08 33.4 0.9 1.5e-07 31.6 0.6 2.2 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III CysA_C_terminal PF17850.1 RLN13970.1 - 0.11 13.1 0.0 0.31 11.6 0.0 1.9 1 0 0 1 1 1 0 CysA C-terminal regulatory domain Ysc84 PF04366.12 RLN13971.1 - 1.3e-33 115.4 0.3 2.2e-33 114.8 0.3 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator FYVE PF01363.21 RLN13971.1 - 3.1e-12 46.5 4.0 3.1e-12 46.5 4.0 3.2 3 0 0 3 3 3 1 FYVE zinc finger zf-ribbon_3 PF13248.6 RLN13971.1 - 0.019 14.4 2.2 0.019 14.4 2.2 3.2 2 1 0 2 2 2 0 zinc-ribbon domain zf-RING_13 PF17977.1 RLN13971.1 - 0.25 11.5 5.6 0.2 11.8 0.8 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_2 PF14445.6 RLN13971.1 - 6.1 7.1 12.2 0.1 12.8 3.9 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 HypA PF01155.19 RLN13971.1 - 6.9 6.7 16.9 0.99 9.4 0.8 3.4 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA EMP24_GP25L PF01105.24 RLN13979.1 - 0.0027 17.7 0.1 0.42 10.5 0.0 2.3 2 0 0 2 2 2 2 emp24/gp25L/p24 family/GOLD Orn_Arg_deC_N PF02784.16 RLN13981.1 - 1.7e-15 57.1 0.0 2.4e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 RLN13981.1 - 3.7e-12 46.3 0.0 5.2e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Mannosyl_trans3 PF11051.8 RLN13992.1 - 9.9e-36 123.5 0.0 8.2e-35 120.5 0.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative HAGH_C PF16123.5 RLN13994.1 - 1.5e-13 51.0 0.0 4.8e-13 49.4 0.0 1.7 2 0 0 2 2 2 1 Hydroxyacylglutathione hydrolase C-terminus PH PF00169.29 RLN13995.1 - 3.2e-18 66.2 0.0 1.5e-07 31.9 0.0 2.7 2 1 0 2 2 2 2 PH domain PH_11 PF15413.6 RLN13995.1 - 7.5e-10 39.2 0.6 7.1e-05 23.2 0.0 2.9 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 RLN13995.1 - 0.00046 20.4 0.6 9.3 6.6 0.3 4.0 3 1 0 3 3 3 2 Pleckstrin homology domain PH_6 PF15406.6 RLN13995.1 - 0.0089 16.3 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Smr PF01713.21 RLN13995.1 - 0.013 15.8 0.1 0.027 14.8 0.1 1.5 1 0 0 1 1 1 0 Smr domain CUE PF02845.16 RLN13996.1 - 1.5e-09 37.4 0.9 3e-05 23.6 0.1 3.8 4 0 0 4 4 4 2 CUE domain UBA PF00627.31 RLN13996.1 - 0.22 11.5 3.2 1.1 9.3 0.1 3.1 3 0 0 3 3 3 0 UBA/TS-N domain DUF3306 PF11748.8 RLN13996.1 - 0.7 10.8 8.7 0.11 13.4 0.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3306) ADP_ribosyl_GH PF03747.14 RLN14020.1 - 1.3e-28 100.6 0.6 1.4e-28 100.5 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase GlcNAc PF11397.8 RLN14021.1 - 1.7e-47 162.6 1.4 2.4e-47 162.1 1.4 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) Glycos_transf_2 PF00535.26 RLN14021.1 - 0.038 13.8 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 GBP_repeat PF02526.14 RLN14023.1 - 0.094 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycophorin-binding protein Gag_p30 PF02093.16 RLN14023.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Gag P30 core shell protein CoaE PF01121.20 RLN14024.1 - 3.4e-42 144.1 0.3 3.4e-42 144.1 0.3 1.8 2 0 0 2 2 2 1 Dephospho-CoA kinase Mnd1 PF03962.15 RLN14024.1 - 1.2e-25 89.5 0.1 6.6e-25 87.2 0.2 2.2 3 0 0 3 3 3 1 Mnd1 HTH domain L31 PF09784.9 RLN14024.1 - 0.075 13.5 1.2 0.23 11.9 1.2 1.8 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 MRP-L51 PF10244.9 RLN14024.1 - 1.6 9.0 4.1 0.63 10.3 0.2 2.2 2 1 0 2 2 2 0 Mitochondrial ribosomal subunit DUF1664 PF07889.12 RLN14024.1 - 8.1 6.5 7.8 0.62 10.1 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SPRY PF00622.28 RLN14025.1 - 0.0015 18.6 0.0 0.0023 18.0 0.0 1.3 1 0 0 1 1 1 1 SPRY domain DUF3712 PF12505.8 RLN14026.1 - 4.1e-11 43.2 0.1 2.4e-10 40.7 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3712) Synaptobrevin PF00957.21 RLN14026.1 - 0.048 13.4 2.5 0.13 12.1 2.5 1.6 1 0 0 1 1 1 0 Synaptobrevin P5-ATPase PF12409.8 RLN14026.1 - 0.18 11.9 0.1 0.49 10.5 0.1 1.7 1 0 0 1 1 1 0 P5-type ATPase cation transporter DUF3139 PF11337.8 RLN14026.1 - 0.55 10.9 3.2 1.1 10.0 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Ferric_reduct PF01794.19 RLN14027.1 - 1.5e-16 60.6 11.7 5.3e-16 58.9 11.7 2.0 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 RLN14027.1 - 5.5e-11 42.8 0.0 3.1e-10 40.4 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 RLN14027.1 - 2.2e-05 24.5 0.0 4.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 RLN14027.1 - 6.3e-05 23.6 0.0 0.0024 18.5 0.0 3.0 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain DOMON PF03351.17 RLN14027.1 - 0.0017 18.6 0.0 0.0048 17.1 0.0 1.8 2 0 0 2 2 2 1 DOMON domain FAD_binding_6 PF00970.24 RLN14027.1 - 0.0083 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain DUF4079 PF13301.6 RLN14027.1 - 2.6 8.2 8.0 0.2 11.8 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) DUF5373 PF17343.2 RLN14027.1 - 3.4 7.5 8.4 9.2 6.1 8.4 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5373) DUF4405 PF14358.6 RLN14027.1 - 6.1 7.5 18.7 0.18 12.4 4.8 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) Collagen PF01391.18 RLN14028.1 - 0.33 10.7 9.2 0.78 9.6 9.2 1.6 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) UPF0047 PF01894.17 RLN14029.1 - 4.5e-15 55.8 0.0 4.7e-15 55.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 UCH PF00443.29 RLN14030.1 - 3.7e-50 170.8 0.1 1.7e-49 168.7 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN14030.1 - 2e-21 77.0 0.1 1e-20 74.6 0.0 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Myb_DNA-binding PF00249.31 RLN14033.1 - 0.00074 19.7 0.2 0.0019 18.3 0.1 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 RLN14034.1 - 3.3e-05 24.0 0.1 6.3e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Nup_retrotrp_bd PF10599.9 RLN14034.1 - 0.058 14.1 3.2 0.15 12.8 3.2 1.8 1 0 0 1 1 1 0 Retro-transposon transporting motif DUF2559 PF10832.8 RLN14034.1 - 0.085 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2559) DDE_Tnp_1_7 PF13843.6 RLN14035.1 - 0.012 14.9 0.1 0.016 14.5 0.1 1.1 1 0 0 1 1 1 0 Transposase IS4 CBM_1 PF00734.18 RLN14036.1 - 5e-06 26.4 5.3 5e-06 26.4 5.3 5.1 5 2 0 5 5 5 3 Fungal cellulose binding domain Toxin_7 PF05980.12 RLN14036.1 - 0.3 11.4 0.3 0.3 11.4 0.3 3.5 4 0 0 4 4 4 0 Toxin 7 PNGaseA PF12222.8 RLN14037.1 - 5.3e-87 292.5 1.8 1.9e-86 290.7 1.8 1.7 1 1 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Myb_DNA-binding PF00249.31 RLN14038.1 - 6.3e-07 29.5 0.1 1.4e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 RLN14039.1 - 3.1e-05 24.1 0.1 6e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Nup_retrotrp_bd PF10599.9 RLN14039.1 - 0.055 14.1 3.2 0.14 12.9 3.2 1.7 1 0 0 1 1 1 0 Retro-transposon transporting motif DUF2559 PF10832.8 RLN14039.1 - 0.08 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2559) DUF2293 PF10056.9 RLN14049.1 - 0.1 12.9 1.5 0.79 10.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2293) Dict-STAT-coil PF09267.10 RLN14049.1 - 0.1 13.0 2.8 0.41 11.0 0.1 2.3 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil BAG PF02179.16 RLN14050.1 - 2.6e-08 34.2 0.7 7.8e-08 32.6 0.7 1.9 1 1 0 1 1 1 1 BAG domain Nop14 PF04147.12 RLN14050.1 - 0.008 14.5 20.4 0.011 14.0 20.4 1.1 1 0 0 1 1 1 1 Nop14-like family Mpp10 PF04006.12 RLN14050.1 - 0.015 13.7 20.8 0.02 13.4 20.8 1.1 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 RLN14050.1 - 0.05 11.9 18.0 0.068 11.5 18.0 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 RLN14050.1 - 0.65 9.3 21.2 0.94 8.8 21.2 1.2 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 RLN14050.1 - 0.77 8.5 8.8 0.98 8.1 8.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CCSAP PF15748.5 RLN14050.1 - 0.77 9.9 11.5 1.2 9.2 11.5 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PPP4R2 PF09184.11 RLN14050.1 - 0.89 9.1 19.7 1.3 8.5 19.7 1.3 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 RLN14050.1 - 0.91 9.4 17.2 1.3 8.9 17.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 RLN14050.1 - 1.1 8.7 10.9 1.7 8.1 10.9 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 RLN14050.1 - 1.6 7.4 5.9 2 7.1 5.9 1.1 1 0 0 1 1 1 0 Presenilin Na_trans_assoc PF06512.13 RLN14050.1 - 2.3 8.5 18.8 4.2 7.6 18.8 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated DUF4746 PF15928.5 RLN14050.1 - 2.4 7.5 13.3 5.1 6.4 13.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF913 PF06025.12 RLN14050.1 - 2.8 6.8 6.3 4.3 6.2 6.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 RLN14050.1 - 9.6 5.9 12.0 15 5.3 12.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pkinase_Tyr PF07714.17 RLN14051.1 - 3.4e-27 95.4 0.0 5.2e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN14051.1 - 3.4e-18 66.0 0.0 5.1e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PDZ_6 PF17820.1 RLN14051.1 - 3.9e-06 26.6 0.1 9.6e-06 25.4 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RLN14051.1 - 1.4e-05 25.4 0.1 2.6e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Laminin_G_3 PF13385.6 RLN14051.1 - 0.0068 16.6 0.0 0.038 14.1 0.0 2.2 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Kdo PF06293.14 RLN14051.1 - 0.069 12.5 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PDZ_2 PF13180.6 RLN14051.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 PDZ domain APH PF01636.23 RLN14051.1 - 5.2 6.9 21.2 0.044 13.7 4.0 3.6 2 2 1 3 3 3 0 Phosphotransferase enzyme family zf-UBR PF02207.20 RLN14052.1 - 1.3e-19 70.1 9.6 1.3e-19 70.1 9.6 2.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 RLN14052.1 - 0.048 13.4 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS Pox_RNA_Pol_19 PF05320.12 RLN14052.1 - 0.4 10.6 2.3 1.3 9.0 2.3 1.8 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Ribosomal_L19e PF01280.20 RLN14053.1 - 0.041 13.9 0.6 0.041 13.9 0.6 1.7 2 0 0 2 2 2 0 Ribosomal protein L19e Med9 PF07544.13 RLN14053.1 - 0.16 12.1 2.8 7.3 6.8 0.8 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 tRNA_lig_CPD PF08302.11 RLN14054.1 - 7.2e-05 22.4 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_33 PF13671.6 RLN14054.1 - 0.00029 21.0 0.0 0.0014 18.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN14054.1 - 0.0034 17.8 0.2 0.03 14.7 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 RLN14054.1 - 0.024 13.9 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF5044 PF16447.5 RLN14054.1 - 0.026 14.3 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5044) AAA_18 PF13238.6 RLN14054.1 - 0.033 14.7 0.0 0.075 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ctr PF04145.15 RLN14056.1 - 6.3e-22 78.8 0.6 1e-21 78.1 0.6 1.3 1 0 0 1 1 1 1 Ctr copper transporter family PetM PF08041.11 RLN14056.1 - 0.0067 16.0 1.9 0.0067 16.0 1.9 1.9 2 0 0 2 2 2 1 PetM family of cytochrome b6f complex subunit 7 zf-Di19 PF05605.12 RLN14056.1 - 0.0071 16.6 0.3 6.7 7.1 0.0 2.8 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding OrfB_Zn_ribbon PF07282.11 RLN14056.1 - 0.013 15.4 0.5 0.58 10.1 0.0 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Rad50_zn_hook PF04423.14 RLN14056.1 - 0.077 12.8 0.4 2.7 7.9 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif Golgin_A5 PF09787.9 RLN14056.1 - 0.23 10.9 0.1 0.3 10.5 0.1 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Zn-C2H2_12 PF18112.1 RLN14056.1 - 0.69 10.4 6.5 13 6.3 0.2 3.5 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain UPF0220 PF05255.11 RLN14056.1 - 1.1 8.8 5.1 0.21 11.1 0.3 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0220) zf-H2C2_2 PF13465.6 RLN14056.1 - 9.7 6.8 8.3 11 6.7 0.2 3.8 4 0 0 4 4 4 0 Zinc-finger double domain LysM PF01476.20 RLN14057.1 - 1.9e-24 85.5 0.0 1.5e-08 34.5 0.0 4.3 4 0 0 4 4 4 4 LysM domain ZnuA PF01297.17 RLN14057.1 - 0.033 13.6 0.1 0.065 12.6 0.1 1.5 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic Ctr PF04145.15 RLN14058.1 - 0.036 14.7 1.9 0.047 14.3 0.3 2.0 3 0 0 3 3 3 0 Ctr copper transporter family YHS PF04945.13 RLN14058.1 - 0.049 13.7 0.3 1.6 8.9 0.0 2.7 2 0 0 2 2 2 0 YHS domain zf-Mss51 PF13824.6 RLN14058.1 - 0.053 13.6 0.5 0.18 11.9 0.5 1.9 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 TF_Zn_Ribbon PF08271.12 RLN14058.1 - 0.61 9.6 6.1 0.38 10.3 0.7 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding FSA_C PF10479.9 RLN14058.1 - 5.5 5.0 11.4 7 4.7 11.4 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Dimer_Tnp_hAT PF05699.14 RLN14064.1 - 9.9e-11 41.3 0.0 2.3e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region AAA_22 PF13401.6 RLN14065.1 - 0.087 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RLN14065.1 - 0.16 12.3 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain LMBR1 PF04791.16 RLN14066.1 - 0.14 11.0 4.7 0.19 10.6 4.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Adenine_glyco PF03352.13 RLN14066.1 - 0.21 11.3 1.9 1.4 8.6 1.9 2.1 1 1 0 1 1 1 0 Methyladenine glycosylase Ank_2 PF12796.7 RLN14099.1 - 2.3e-38 130.6 8.4 4.3e-08 33.6 0.1 6.1 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN14099.1 - 4.1e-35 119.7 12.8 6.9e-05 23.3 0.0 10.6 7 1 4 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN14099.1 - 9.1e-34 115.1 27.4 0.0031 17.8 0.3 14.1 3 2 11 14 14 14 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN14099.1 - 2.7e-21 73.4 5.8 0.58 10.9 0.1 14.1 12 2 3 15 15 15 2 Ankyrin repeat Ank PF00023.30 RLN14099.1 - 3.1e-06 27.4 1.1 10 6.7 0.1 8.7 4 3 3 7 7 7 1 Ankyrin repeat DUF5049 PF16468.5 RLN14099.1 - 0.0002 21.2 0.0 41 4.2 0.0 5.9 3 2 4 7 7 7 0 Domain of unknown function (DUF5049) TGBp3 PF02495.17 RLN14099.1 - 0.61 9.8 2.6 46 3.8 0.0 4.8 8 0 0 8 8 8 0 Triple gene block 3 Zip PF02535.22 RLN14105.1 - 8.2e-30 104.1 5.4 2.2e-29 102.8 5.4 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter Cu-oxidase_2 PF07731.14 RLN14105.1 - 2.3e-12 46.8 3.1 2e-11 43.8 3.1 2.4 1 1 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN14105.1 - 3.1e-10 40.1 2.8 1.3e-07 31.6 0.1 3.1 3 0 0 3 3 3 2 Multicopper oxidase Plasmid_stab_B PF10784.9 RLN14105.1 - 0.19 11.6 0.2 0.62 9.9 0.0 1.9 2 0 0 2 2 2 0 Plasmid stability protein WD40 PF00400.32 RLN14108.1 - 2.8e-14 53.2 5.8 2.2e-06 28.3 0.1 5.0 4 1 0 4 4 4 4 WD domain, G-beta repeat Peptidase_C74 PF12387.8 RLN14109.1 - 0.15 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Pestivirus NS2 peptidase DIRP PF06584.13 RLN14109.1 - 0.3 11.3 3.3 0.67 10.2 3.3 1.6 1 0 0 1 1 1 0 DIRP Sel1 PF08238.12 RLN14110.1 - 3.3e-40 135.6 35.1 4.3e-06 27.2 4.0 10.2 10 1 0 10 10 10 7 Sel1 repeat TPR_1 PF00515.28 RLN14110.1 - 0.03 14.2 13.5 15 5.6 0.0 6.4 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN14110.1 - 0.57 10.4 22.6 9.6 6.6 0.3 7.3 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN14110.1 - 1.1 10.3 12.1 11 7.1 0.1 6.6 6 1 1 7 7 7 0 Tetratricopeptide repeat FYVE PF01363.21 RLN14111.1 - 0.034 14.3 8.4 0.069 13.3 8.4 1.5 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN14111.1 - 0.083 13.1 5.1 0.15 12.3 5.1 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger IBR PF01485.21 RLN14111.1 - 0.13 12.5 3.7 0.29 11.4 3.7 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Pyr_redox_2 PF07992.14 RLN14112.1 - 0.028 13.7 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase B12-binding PF02310.19 RLN14112.1 - 0.092 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 B12 binding domain Utp12 PF04003.12 RLN14114.1 - 0.026 14.8 0.1 0.073 13.4 0.1 1.7 1 0 0 1 1 1 0 Dip2/Utp12 Family Poxvirus PF06227.12 RLN14116.1 - 0.034 13.9 0.1 0.056 13.2 0.1 1.4 1 1 0 1 1 1 0 dsDNA Poxvirus DNA_pack_C PF02499.15 RLN14116.1 - 0.079 11.9 0.0 0.081 11.9 0.0 1.0 1 0 0 1 1 1 0 Probable DNA packing protein, C-terminus Salp15 PF12115.8 RLN14116.1 - 0.085 13.3 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Peptidase_C1 PF00112.23 RLN14117.1 - 3.2e-40 138.5 5.1 2e-39 135.9 3.8 2.3 2 1 0 2 2 2 1 Papain family cysteine protease Phage_holin_2_1 PF04971.12 RLN14117.1 - 0.00089 19.2 0.5 0.00089 19.2 0.5 2.6 2 1 0 2 2 2 1 Bacteriophage P21 holin S Peptidase_C1_2 PF03051.15 RLN14117.1 - 0.0011 17.8 0.3 0.54 9.0 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Phage_holin_2_2 PF10746.9 RLN14117.1 - 0.041 13.6 0.4 0.087 12.5 0.4 1.5 1 0 0 1 1 1 0 Phage holin T7 family, holin superfamily II MLTR_LBD PF17765.1 RLN14117.1 - 0.072 13.2 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain GATase_7 PF13537.6 RLN14117.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain Mito_carr PF00153.27 RLN14118.1 - 4e-59 196.5 0.1 2.9e-22 78.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C1 PF00112.23 RLN14119.1 - 1.5e-42 146.1 8.5 3.2e-41 141.8 8.5 2.2 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RLN14119.1 - 0.0009 18.1 3.7 0.12 11.1 0.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family DUF1631 PF07793.11 RLN14120.1 - 0.014 13.9 0.2 0.014 13.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) RSB_motif PF16294.5 RLN14154.1 - 1.4e-12 47.7 2.2 1.4e-12 47.7 2.2 4.1 2 2 3 5 5 5 1 RNSP1-SAP18 binding (RSB) motif HEAT_2 PF13646.6 RLN14155.1 - 6.2e-16 58.6 5.7 0.00013 22.3 0.2 7.1 6 1 2 8 8 8 4 HEAT repeats HEAT PF02985.22 RLN14155.1 - 3.7e-13 48.5 22.0 0.36 11.2 0.2 11.3 11 0 0 11 11 11 4 HEAT repeat DUF4042 PF13251.6 RLN14155.1 - 6.3e-11 42.3 13.7 1.3e-10 41.2 0.6 6.0 6 2 1 7 7 7 1 Domain of unknown function (DUF4042) RTP1_C1 PF10363.9 RLN14155.1 - 3.1e-05 24.1 0.0 0.18 12.0 0.0 3.8 4 0 0 4 4 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 RLN14155.1 - 0.00036 20.2 0.0 0.0019 17.8 0.0 2.3 2 0 0 2 2 2 1 Tti2 family Vac14_Fab1_bd PF12755.7 RLN14155.1 - 0.00067 20.2 0.1 22 5.7 0.0 5.9 8 0 0 8 8 7 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 RLN14155.1 - 0.0014 19.1 23.1 0.22 12.1 1.0 9.3 10 2 1 11 11 11 2 HEAT-like repeat HEAT_PBS PF03130.16 RLN14155.1 - 0.0019 18.7 2.6 0.39 11.5 0.1 4.8 4 0 0 4 4 3 1 PBS lyase HEAT-like repeat TAF6_C PF07571.13 RLN14155.1 - 0.034 14.5 0.8 7.5 7.0 0.1 4.4 5 0 0 5 5 4 0 TAF6 C-terminal HEAT repeat domain Sec7_N PF12783.7 RLN14155.1 - 0.062 13.2 0.2 2.8 7.8 0.0 3.7 3 1 1 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal V-ATPase_H_N PF03224.14 RLN14155.1 - 0.069 12.4 0.2 0.32 10.2 0.0 2.1 2 0 0 2 2 2 0 V-ATPase subunit H Arm PF00514.23 RLN14155.1 - 2 8.5 8.1 6.4 7.0 0.5 4.3 5 0 0 5 5 4 0 Armadillo/beta-catenin-like repeat WD40 PF00400.32 RLN14156.1 - 9.3e-08 32.6 9.6 0.00017 22.3 1.0 5.6 5 1 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN14156.1 - 2.8e-05 24.3 0.1 0.00059 20.1 0.0 2.6 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 RLN14156.1 - 0.00062 19.4 0.6 0.0019 17.8 0.5 2.0 1 1 1 2 2 2 2 PQQ-like domain FYVE PF01363.21 RLN14157.1 - 1e-09 38.4 9.6 1e-09 38.4 9.6 2.2 2 0 0 2 2 2 1 FYVE zinc finger GAF PF01590.26 RLN14157.1 - 1.7e-07 32.0 0.2 2.6e-06 28.1 0.1 2.6 2 0 0 2 2 2 1 GAF domain zf-B_box PF00643.24 RLN14157.1 - 0.084 13.0 2.9 0.22 11.7 2.9 1.7 1 0 0 1 1 1 0 B-box zinc finger Prok-RING_4 PF14447.6 RLN14157.1 - 0.14 12.1 4.6 0.47 10.4 4.6 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FYVE_2 PF02318.16 RLN14157.1 - 0.19 12.0 6.1 0.56 10.4 6.1 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_5 PF14634.6 RLN14157.1 - 0.27 11.2 10.5 0.2 11.6 8.4 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 RLN14157.1 - 1.1 9.4 9.5 0.94 9.6 7.3 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 RLN14157.1 - 2 8.8 11.1 1.5 9.2 7.7 2.5 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.25 RLN14157.1 - 4.2 7.3 7.5 14 5.6 7.5 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TTL PF03133.15 RLN14159.1 - 1.7e-69 234.2 0.0 9.9e-51 172.6 0.0 2.6 3 0 0 3 3 3 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RLN14159.1 - 6.3e-07 28.9 0.1 3.1e-05 23.4 0.0 2.9 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RLN14159.1 - 0.037 13.3 0.0 0.16 11.2 0.0 1.9 2 1 1 3 3 3 0 Sugar-transfer associated ATP-grasp FYVE PF01363.21 RLN14160.1 - 2.6e-10 40.3 9.1 2.6e-10 40.3 9.1 2.0 2 0 0 2 2 2 1 FYVE zinc finger zf-RING_5 PF14634.6 RLN14160.1 - 0.01 15.8 8.6 0.028 14.4 8.6 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 RLN14160.1 - 0.2 11.6 4.6 0.74 9.7 4.6 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 RLN14160.1 - 0.2 11.7 6.5 0.6 10.2 6.5 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 RLN14160.1 - 0.9 9.9 9.6 1.6 9.1 7.9 2.4 2 0 0 2 2 2 0 Ring finger domain Zn_ribbon_17 PF17120.5 RLN14160.1 - 2.6 7.7 10.5 0.047 13.3 2.8 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 RLN14160.1 - 6.7 6.7 8.0 18 5.3 8.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 RLN14161.1 - 0.00083 19.4 11.9 0.00083 19.4 11.9 1.8 1 1 0 1 1 1 1 FYVE zinc finger DUF776 PF05604.11 RLN14161.1 - 0.063 13.7 1.0 0.11 12.8 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF776) zf-C4pol PF14260.6 RLN14161.1 - 1.8 9.1 11.2 1.1 9.7 5.4 2.6 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta FYVE_2 PF02318.16 RLN14161.1 - 5.4 7.3 11.2 7.6 6.8 9.2 2.1 1 1 1 2 2 2 0 FYVE-type zinc finger Utp21 PF04192.12 RLN14197.1 - 1.7e-50 171.7 5.0 3.3e-50 170.7 5.0 1.4 1 1 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 RLN14197.1 - 8.1e-21 74.0 6.8 6.7e-06 26.7 0.1 7.8 8 1 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN14197.1 - 3.1e-10 40.2 0.0 0.00075 19.7 0.0 5.4 4 1 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN14197.1 - 0.00032 19.5 1.6 0.47 9.0 0.1 3.2 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 RLN14197.1 - 0.025 13.1 0.0 0.21 10.1 0.0 2.1 1 1 1 2 2 2 0 Cytochrome D1 heme domain FGF PF00167.18 RLN14198.1 - 0.025 14.7 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Fibroblast growth factor Mito_carr PF00153.27 RLN14200.1 - 3.8e-28 97.2 0.6 2.1e-07 30.8 0.1 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein MULE PF10551.9 RLN14201.1 - 3.1e-11 43.6 0.2 3.1e-11 43.6 0.2 2.2 2 0 0 2 2 2 1 MULE transposase domain DUF2353 PF09789.9 RLN14201.1 - 0.0012 18.3 28.8 0.0087 15.5 26.7 2.4 1 1 1 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) SCAB-Ig PF16709.5 RLN14201.1 - 0.023 14.7 0.0 0.094 12.8 0.0 2.1 2 0 0 2 2 2 0 Ig domain of plant-specific actin-binding protein PDZ_6 PF17820.1 RLN14201.1 - 0.12 12.2 0.0 0.36 10.7 0.0 1.8 1 0 0 1 1 1 0 PDZ domain TPR_MLP1_2 PF07926.12 RLN14201.1 - 0.81 9.8 36.3 0.2 11.7 14.9 2.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Molybdopterin_N PF18364.1 RLN14203.1 - 0.25 11.4 4.5 6.7 6.8 0.3 3.4 1 1 3 4 4 4 0 Molybdopterin oxidoreductase N-terminal domain Dimer_Tnp_hAT PF05699.14 RLN14204.1 - 8.8e-06 25.4 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF2753 PF10952.8 RLN14204.1 - 0.067 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) Peptidase_C1 PF00112.23 RLN14205.1 - 2e-53 181.7 0.2 2.7e-53 181.3 0.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RLN14205.1 - 0.0006 18.7 0.2 0.14 10.9 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Inhibitor_I29 PF08246.12 RLN14205.1 - 0.062 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) Hid1 PF12722.7 RLN14206.1 - 3.8e-62 210.6 5.2 1.8e-30 105.8 5.7 2.0 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 RLN14206.1 - 1.1e-59 202.4 0.3 1.3e-59 202.3 0.3 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein RhoGAP PF00620.27 RLN14207.1 - 1.4e-14 54.2 0.1 6.6e-14 52.0 0.0 2.1 3 0 0 3 3 3 1 RhoGAP domain Exo_endo_phos PF03372.23 RLN14207.1 - 2.5e-09 37.0 0.0 4.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Vps5 PF09325.10 RLN14208.1 - 2.6e-33 115.5 0.2 3.8e-33 115.0 0.2 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 RLN14208.1 - 5.2e-30 103.7 0.1 9.4e-30 102.9 0.1 1.4 1 0 0 1 1 1 1 PX domain BAR PF03114.18 RLN14208.1 - 0.00018 21.3 0.4 0.00029 20.5 0.4 1.3 1 0 0 1 1 1 1 BAR domain BAR_3_WASP_bdg PF10456.9 RLN14208.1 - 0.0019 17.7 1.1 0.013 15.0 1.1 2.1 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein FAM92 PF06730.11 RLN14208.1 - 0.045 13.2 0.3 0.072 12.5 0.3 1.3 1 0 0 1 1 1 0 FAM92 protein zf-BED PF02892.15 RLN14211.1 - 0.0019 18.1 7.7 0.15 12.1 0.3 3.9 3 1 0 3 3 3 2 BED zinc finger F-box_4 PF15966.5 RLN14211.1 - 0.097 12.6 0.2 4.4 7.2 0.0 3.2 3 0 0 3 3 3 0 F-box zf_C2HC_14 PF18574.1 RLN14211.1 - 0.79 9.6 5.8 0.57 10.0 0.3 3.3 3 0 0 3 3 3 0 C2HC Zing finger domain zf-U11-48K PF05253.12 RLN14211.1 - 2.6 8.0 7.5 2 8.4 0.1 3.1 3 0 0 3 3 3 0 U11-48K-like CHHC zinc finger zf-HC2 PF13490.6 RLN14211.1 - 6.1 7.2 8.9 32 4.9 0.0 4.5 5 0 0 5 5 5 0 Putative zinc-finger FAA_hydrolase PF01557.18 RLN14212.1 - 2e-39 135.5 0.0 9.6e-37 126.8 0.0 2.1 1 1 1 2 2 2 2 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 RLN14212.1 - 1.5e-09 37.9 0.3 3e-09 37.0 0.3 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal FAA_hydrolase_N PF09298.11 RLN14213.1 - 1.1e-09 38.5 0.0 1.5e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal HPS3_N PF14761.6 RLN14214.1 - 0.014 14.9 12.6 3.2 7.2 0.6 3.5 3 0 0 3 3 3 0 Hermansky-Pudlak syndrome 3 Ribosomal_L14 PF00238.19 RLN14214.1 - 1.6 8.9 5.4 1e+02 3.0 0.1 3.7 3 0 0 3 3 3 0 Ribosomal protein L14p/L23e Sugar_tr PF00083.24 RLN14215.1 - 1.2e-20 73.8 10.4 1.4e-20 73.7 10.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN14215.1 - 0.0022 17.0 1.4 0.0025 16.8 1.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SpoU_methylase PF00588.19 RLN14216.1 - 1.1e-18 67.7 0.0 2.3e-17 63.5 0.0 2.3 1 1 0 1 1 1 1 SpoU rRNA Methylase family LRR_6 PF13516.6 RLN14217.1 - 2.5e-14 52.0 7.4 0.1 12.7 0.0 8.1 8 0 0 8 8 8 5 Leucine Rich repeat LRR_8 PF13855.6 RLN14217.1 - 0.00041 20.0 13.3 0.00063 19.4 1.8 4.5 4 2 1 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 RLN14217.1 - 0.0063 16.9 4.9 1.4e+02 3.7 0.2 6.7 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 RLN14217.1 - 0.011 16.2 11.5 0.29 11.6 0.0 4.5 3 1 0 4 4 4 0 Leucine Rich repeats (2 copies) ANAPC_CDC26 PF10471.9 RLN14218.1 - 1.4 9.8 6.2 4.1 8.3 6.2 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 MRI PF15325.6 RLN14218.1 - 3.6 8.7 8.7 0.98 10.5 4.4 1.9 1 1 1 2 2 2 0 Modulator of retrovirus infection MIP-T3 PF10243.9 RLN14219.1 - 1.8e-78 259.9 3.2 5.8e-39 132.6 0.0 3.2 3 0 0 3 3 3 2 Microtubule-binding protein MIP-T3 CH-like domain MIP-T3_C PF17749.1 RLN14219.1 - 2e-37 128.5 4.7 4.8e-37 127.3 4.7 1.7 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 C-terminal region Fib_alpha PF08702.10 RLN14219.1 - 0.0091 16.2 2.7 0.021 15.0 2.7 1.6 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Tektin PF03148.14 RLN14219.1 - 0.011 14.5 4.9 0.024 13.4 4.9 1.5 1 0 0 1 1 1 0 Tektin family SOGA PF11365.8 RLN14219.1 - 0.022 15.9 2.5 0.11 13.7 2.5 2.2 1 0 0 1 1 1 0 Protein SOGA Tsc35 PF15079.6 RLN14219.1 - 0.054 13.1 1.8 0.12 12.0 1.8 1.5 1 0 0 1 1 1 0 Testis-specific protein 35 DUF1732 PF08340.11 RLN14219.1 - 0.074 13.1 0.9 0.26 11.3 0.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) DUF812 PF05667.11 RLN14219.1 - 0.13 11.2 8.5 0.22 10.3 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) UPF0242 PF06785.11 RLN14219.1 - 0.25 11.4 5.6 0.53 10.4 5.6 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SesA PF17107.5 RLN14219.1 - 1.2 9.3 5.7 1.2 9.3 0.1 2.9 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases MAP65_ASE1 PF03999.12 RLN14219.1 - 1.4 7.6 10.6 1.5 7.4 2.1 2.7 3 0 0 3 3 3 0 Microtubule associated protein (MAP65/ASE1 family) Mod_r PF07200.13 RLN14219.1 - 1.6 8.8 9.0 0.62 10.2 5.2 2.3 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein EMP24_GP25L PF01105.24 RLN14219.1 - 3.3 7.6 5.0 17 5.3 5.0 2.0 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF16 PF01519.16 RLN14219.1 - 9.7 6.7 7.6 45 4.6 6.9 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 Alpha_adaptin_C PF02296.16 RLN14220.1 - 0.16 12.2 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain Ist1 PF03398.14 RLN14221.1 - 3.6e-60 202.6 1.2 4.8e-60 202.2 1.2 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Pectate_lyase PF03211.13 RLN14224.1 - 4.5e-06 26.3 0.1 4.5e-06 26.3 0.1 2.1 2 1 0 2 2 2 1 Pectate lyase PPP4R2 PF09184.11 RLN14224.1 - 0.01 15.5 35.0 0.012 15.2 35.0 1.2 1 0 0 1 1 1 0 PPP4R2 SprA-related PF12118.8 RLN14224.1 - 0.29 10.2 27.1 0.32 10.1 27.1 1.1 1 0 0 1 1 1 0 SprA-related family Hamartin PF04388.12 RLN14224.1 - 0.54 8.8 16.0 0.57 8.8 16.0 1.0 1 0 0 1 1 1 0 Hamartin protein DUF2981 PF11200.8 RLN14224.1 - 3 7.5 12.1 3.5 7.3 12.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) RIC1 PF07064.13 RLN14225.1 - 2.3e-17 63.3 0.1 1.2e-16 60.9 0.1 2.1 1 1 0 1 1 1 1 RIC1 ACBP PF00887.19 RLN14225.1 - 2.9e-09 37.0 0.0 7.5e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Acyl CoA binding protein PDZ PF00595.24 RLN14225.1 - 0.00014 22.2 0.1 0.00033 21.0 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RLN14225.1 - 0.00017 21.4 0.5 0.00046 20.0 0.5 1.7 1 0 0 1 1 1 1 PDZ domain ANAPC4_WD40 PF12894.7 RLN14225.1 - 0.0013 19.0 0.0 0.12 12.7 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain BolA PF01722.18 RLN14226.1 - 0.032 14.5 0.0 0.098 13.0 0.0 1.8 1 1 0 1 1 1 0 BolA-like protein Big_6 PF17936.1 RLN14232.1 - 0.0064 16.7 0.9 0.0087 16.3 0.9 1.2 1 0 0 1 1 1 1 Bacterial Ig domain Mannitol_dh_C PF08125.13 RLN14233.1 - 0.12 11.8 0.1 1 8.8 0.1 2.0 1 1 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain Mannitol_dh_C PF08125.13 RLN14234.1 - 4.3e-08 33.0 0.1 8.4e-07 28.7 0.1 2.1 1 1 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Ank_2 PF12796.7 RLN14235.1 - 7.6e-68 225.1 15.6 2.5e-16 60.0 0.1 6.2 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN14235.1 - 1.7e-58 194.2 15.8 9.5e-09 35.6 0.0 8.5 2 2 8 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN14235.1 - 3e-45 151.7 15.2 5e-07 29.9 0.0 10.7 1 1 10 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 RLN14235.1 - 1.4e-41 139.2 23.3 0.00022 21.5 0.0 11.7 10 1 1 11 11 11 9 Ankyrin repeat Ank_3 PF13606.6 RLN14235.1 - 1.2e-36 120.5 11.0 0.031 14.8 0.0 12.6 12 0 0 12 12 12 9 Ankyrin repeat Pkinase PF00069.25 RLN14235.1 - 1.9e-07 30.7 0.0 6.8e-07 28.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN14235.1 - 2.1e-06 27.2 0.0 9.3e-05 21.8 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1949 PF09186.11 RLN14235.1 - 2.9e-05 23.8 0.5 16 5.5 0.0 5.3 5 0 0 5 5 5 1 Domain of unknown function (DUF1949) SIP PF04954.13 RLN14235.1 - 0.00033 21.1 0.1 1.9 9.0 0.0 3.5 2 1 0 3 3 3 2 Siderophore-interacting protein DUF4926 PF16277.5 RLN14235.1 - 0.01 15.2 0.0 69 2.9 0.1 5.3 6 0 0 6 6 6 0 Domain of unknown function (DUF4926) MTS PF05175.14 RLN14235.1 - 6.6 6.2 13.4 2.4 7.7 0.5 4.0 1 1 2 4 4 4 0 Methyltransferase small domain Pico_P1A PF02226.16 RLN14249.1 - 0.00016 21.6 0.1 1.3 9.2 0.0 2.8 2 0 0 2 2 2 2 Picornavirus coat protein (VP4) Rhodanese PF00581.20 RLN14249.1 - 0.034 14.7 0.0 7.2 7.2 0.0 2.6 2 0 0 2 2 2 0 Rhodanese-like domain DUF973 PF06157.11 RLN14249.1 - 0.04 13.0 0.0 11 5.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF973) LSDAT_euk PF18139.1 RLN14249.1 - 0.19 11.1 1.1 17 4.7 0.1 2.3 2 0 0 2 2 2 0 SLOG in TRPM Glyco_hydro_17 PF00332.18 RLN14250.1 - 9.2e-31 107.6 2.3 1.3e-10 41.4 0.2 4.2 3 1 0 3 3 3 3 Glycosyl hydrolases family 17 DUF2314 PF10077.9 RLN14250.1 - 0.12 12.5 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2314) Sugar_tr PF00083.24 RLN14251.1 - 1.3e-100 337.4 20.6 1.5e-100 337.2 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN14251.1 - 3.8e-21 75.4 44.6 2e-16 59.9 10.0 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily Pkinase_Tyr PF07714.17 RLN14268.1 - 3.7e-54 183.7 0.0 5.4e-41 140.6 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN14268.1 - 3.1e-44 151.3 0.0 7.4e-34 117.3 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Arm PF00514.23 RLN14268.1 - 5.2e-36 121.6 18.7 0.0012 18.8 0.0 13.3 14 0 0 14 14 14 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN14268.1 - 1.4e-05 25.4 33.5 0.15 12.5 0.8 6.9 3 2 1 6 6 6 4 HEAT repeats HEAT_EZ PF13513.6 RLN14268.1 - 0.0025 18.3 30.7 0.24 11.9 0.2 8.4 7 1 2 9 9 9 3 HEAT-like repeat HEAT PF02985.22 RLN14268.1 - 0.046 14.0 10.0 61 4.3 0.0 8.2 9 0 0 9 9 9 0 HEAT repeat MoaE PF02391.17 RLN14268.1 - 0.071 13.4 0.0 13 6.1 0.0 3.8 3 0 0 3 3 3 0 MoaE protein Sugar_tr PF00083.24 RLN14269.1 - 5.5e-07 28.8 0.1 6.5e-07 28.6 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN14269.1 - 0.0034 16.4 0.1 0.004 16.1 0.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_Mycoplasma PF07672.13 RLN14269.1 - 0.037 13.3 0.0 0.044 13.1 0.0 1.0 1 0 0 1 1 1 0 Mycoplasma MFS transporter LCM PF04072.14 RLN14270.1 - 6e-19 68.7 0.1 8.1e-19 68.3 0.1 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase LCM PF04072.14 RLN14271.1 - 1.9e-40 138.8 0.0 3.2e-40 138.1 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase LCM PF04072.14 RLN14272.1 - 2.5e-39 135.2 0.0 3.5e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Lipase_3 PF01764.25 RLN14317.1 - 2.1e-08 34.1 0.0 4.8e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 RLN14317.1 - 0.013 15.1 0.3 0.098 12.2 0.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 RLN14317.1 - 0.046 13.0 0.0 0.097 11.9 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN14317.1 - 0.096 13.3 0.6 0.38 11.3 0.1 2.2 3 0 0 3 3 3 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 RLN14317.1 - 0.096 12.4 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2048 PF09752.9 RLN14317.1 - 0.15 11.1 0.4 0.5 9.4 0.1 1.9 2 0 0 2 2 2 0 Abhydrolase domain containing 18 tRNA-synt_2 PF00152.20 RLN14318.1 - 6.9e-70 235.6 0.0 8.8e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RLN14318.1 - 0.00013 21.9 0.0 0.00025 21.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 RLN14318.1 - 0.0011 18.5 0.6 2.3 7.6 0.1 3.1 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA_anti_2 PF13742.6 RLN14318.1 - 0.004 17.3 0.0 0.0082 16.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DLH PF01738.18 RLN14319.1 - 5.6e-05 22.8 0.1 0.00066 19.3 0.1 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 RLN14319.1 - 0.0033 16.7 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 RLN14319.1 - 0.0095 15.8 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF4050 PF13259.6 RLN14319.1 - 0.0096 16.3 1.3 0.099 13.0 1.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4050) BAAT_C PF08840.11 RLN14319.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Pox_A_type_inc PF04508.12 RLN14320.1 - 0.0045 16.8 2.8 4.8 7.2 0.0 6.0 4 0 0 4 4 4 2 Viral A-type inclusion protein repeat LPP PF04728.13 RLN14320.1 - 0.14 12.5 0.1 0.14 12.5 0.1 6.8 5 1 1 6 6 6 0 Lipoprotein leucine-zipper Imm42 PF15593.6 RLN14320.1 - 4.2 7.8 10.9 0.19 12.2 0.9 3.6 2 1 1 3 3 3 0 Immunity protein 42 HSP90 PF00183.18 RLN14321.1 - 3.6e-144 481.5 16.9 9.2e-99 331.7 0.6 2.9 1 1 2 3 3 3 2 Hsp90 protein HATPase_c PF02518.26 RLN14321.1 - 9.8e-14 51.8 0.0 2.1e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 RLN14321.1 - 2.1e-09 37.3 0.1 4.8e-09 36.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Presenilin PF01080.17 RLN14321.1 - 1.1 7.9 3.5 1.9 7.2 3.5 1.3 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 RLN14321.1 - 5.9 7.3 8.7 19 5.6 1.8 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Evr1_Alr PF04777.13 RLN14323.1 - 6e-24 84.4 0.7 8.2e-24 84.0 0.7 1.2 1 0 0 1 1 1 1 Erv1 / Alr family TPR_1 PF00515.28 RLN14324.1 - 1.3e-17 62.8 5.0 0.0088 15.8 0.1 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 RLN14324.1 - 4.1e-17 62.2 31.7 1.6e-07 31.5 4.0 4.0 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.6 RLN14324.1 - 1.1e-11 43.8 12.4 0.021 14.9 0.0 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 RLN14324.1 - 1e-10 40.9 1.1 0.15 12.3 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN14324.1 - 1.9e-10 40.0 7.0 0.0062 16.6 0.9 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 RLN14324.1 - 2e-05 24.3 8.4 0.25 11.2 0.4 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 RLN14324.1 - 0.00057 19.4 9.6 0.00081 18.9 9.6 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_14 PF13428.6 RLN14324.1 - 0.0015 19.2 3.7 0.39 11.6 0.6 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat CooC_C PF15976.5 RLN14324.1 - 0.0029 17.6 0.0 0.0059 16.6 0.0 1.6 1 1 0 1 1 1 1 CS1-pili formation C-terminal ANAPC5 PF12862.7 RLN14324.1 - 0.032 14.3 3.9 0.18 11.9 0.2 2.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_17 PF13431.6 RLN14324.1 - 0.19 12.2 1.8 62 4.3 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 RLN14324.1 - 0.28 11.3 3.9 1.3 9.3 0.9 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN14324.1 - 0.72 10.6 8.9 3.2 8.5 0.6 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN14324.1 - 1.4 9.7 4.5 1.5e+02 3.4 0.0 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat WD40 PF00400.32 RLN14325.1 - 5.8e-27 93.4 6.3 5.9e-06 26.9 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN14325.1 - 6.7e-16 58.4 0.3 0.0087 16.3 0.0 5.1 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RLN14325.1 - 1.9e-06 27.9 0.0 0.0023 17.8 0.0 2.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 RLN14325.1 - 1.2e-05 24.0 0.3 0.0086 14.7 0.1 2.7 1 1 1 3 3 3 3 Cytochrome D1 heme domain WD40_like PF17005.5 RLN14325.1 - 0.00016 21.1 0.0 0.064 12.6 0.0 2.5 2 1 0 2 2 2 2 WD40-like domain PALB2_WD40 PF16756.5 RLN14325.1 - 0.0024 16.9 0.1 0.059 12.3 0.0 2.2 1 1 1 2 2 2 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 RLN14325.1 - 0.073 11.4 0.0 0.12 10.6 0.0 1.4 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz ribosomal_L24 PF17136.4 RLN14328.1 - 2.4e-16 59.9 0.0 4.6e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 RLN14328.1 - 7.7e-07 28.9 2.8 7.7e-07 28.9 2.8 1.8 2 0 0 2 2 2 1 KOW motif PELOTA_1 PF15608.6 RLN14328.1 - 0.058 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 PELOTA RNA binding domain CRAL_TRIO PF00650.20 RLN14330.1 - 7.5e-28 97.3 0.0 9.6e-28 96.9 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain RNA_pol_3_Rpc31 PF11705.8 RLN14331.1 - 0.0036 17.6 9.6 0.56 10.4 9.6 2.2 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 RLN14331.1 - 2.7 6.0 8.2 3.5 5.6 8.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Tmemb_14 PF03647.13 RLN14334.1 - 7.9e-18 65.0 10.6 9.4e-18 64.7 10.6 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C UbiA PF01040.18 RLN14334.1 - 0.038 13.3 4.6 0.043 13.1 4.6 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family Rhomboid PF01694.22 RLN14334.1 - 0.97 9.4 6.9 1.3 9.0 6.9 1.3 1 0 0 1 1 1 0 Rhomboid family DUF4113 PF13438.6 RLN14335.1 - 0.15 12.1 0.2 0.51 10.5 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) MBF1 PF08523.10 RLN14336.1 - 3.4e-15 56.2 2.0 9.8e-15 54.8 2.0 1.7 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 RLN14336.1 - 1.4e-12 47.5 0.2 2e-12 46.9 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 RLN14336.1 - 0.00017 21.8 0.0 0.00036 20.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 RLN14336.1 - 0.00053 19.9 0.2 0.0011 18.9 0.1 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain LSM PF01423.22 RLN14337.1 - 7.5e-15 54.4 0.2 9.3e-15 54.1 0.2 1.1 1 0 0 1 1 1 1 LSM domain IQ PF00612.27 RLN14338.1 - 3.6e-12 44.9 96.2 0.0072 16.0 1.7 13.7 10 3 3 13 13 13 10 IQ calmodulin-binding motif REV1_C PF16727.5 RLN14339.1 - 0.044 14.2 11.7 0.17 12.3 1.8 4.1 3 1 1 4 4 4 0 DNA repair protein REV1 C-terminal domain RasGEF_N_2 PF14663.6 RLN14339.1 - 6 7.3 7.9 44 4.5 0.4 3.3 2 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Gar1 PF04410.14 RLN14341.1 - 3.4e-31 108.1 0.0 4.6e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region IMPDH PF00478.25 RLN14343.1 - 9.4e-72 241.9 6.1 2.4e-71 240.5 6.1 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 RLN14343.1 - 1.3e-05 24.4 1.1 1.9e-05 23.8 1.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Aldolase PF01081.19 RLN14343.1 - 0.062 12.7 1.6 0.23 10.9 0.2 2.2 1 1 1 2 2 2 0 KDPG and KHG aldolase GRIM-19 PF06212.12 RLN14345.1 - 1.6e-31 109.0 0.0 1.9e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein Glyco_hydro_77 PF02446.17 RLN14345.1 - 0.13 11.1 0.1 0.16 10.7 0.1 1.0 1 0 0 1 1 1 0 4-alpha-glucanotransferase Rpn3_C PF08375.11 RLN14346.1 - 3.3e-29 101.1 3.0 5.2e-29 100.5 3.0 1.3 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 RLN14346.1 - 2.7e-05 24.6 0.0 5.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 PCI domain Dak1_2 PF13684.6 RLN14346.1 - 0.084 11.9 0.2 0.095 11.8 0.2 1.1 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Cyclin_N PF00134.23 RLN14347.1 - 7.2e-42 142.1 1.3 2.1e-40 137.4 0.6 2.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 RLN14347.1 - 2e-15 56.9 0.1 6.2e-15 55.3 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 RLN14348.1 - 1.4e-28 98.7 0.1 1.6e-13 50.5 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 RLN14348.1 - 1.3e-08 35.1 1.5 1.3e-08 35.1 1.5 3.5 3 1 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 RLN14348.1 - 1.6e-07 30.7 5.3 4.1e-07 29.4 5.3 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 RLN14348.1 - 0.07 12.9 0.4 4.4 7.1 0.0 3.0 2 1 0 2 2 2 0 Cyclin, N-terminal domain MAPKK1_Int PF08923.10 RLN14348.1 - 0.094 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting zf-RRN7 PF11781.8 RLN14348.1 - 0.28 10.9 1.5 0.64 9.8 1.5 1.6 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 HTH_Tnp_Tc5 PF03221.16 RLN14351.1 - 6.7e-10 38.9 0.0 1.7e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_Tnp_1 PF01527.20 RLN14351.1 - 6.4e-07 29.6 0.5 2.7e-05 24.4 0.0 2.9 3 0 0 3 3 3 1 Transposase BrkDBD PF09607.10 RLN14351.1 - 0.00057 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Brinker DNA-binding domain FGGY_N PF00370.21 RLN14351.1 - 0.0013 18.3 0.1 0.77 9.3 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain CENP-B_N PF04218.13 RLN14351.1 - 0.0016 18.0 0.0 0.0041 16.7 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 RLN14351.1 - 0.0079 16.3 0.0 0.022 14.9 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 RLN14351.1 - 0.11 12.3 0.0 0.38 10.6 0.0 1.9 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT E3_binding PF02817.17 RLN14351.1 - 0.12 12.8 0.3 1.9 8.9 0.0 2.6 2 1 0 2 2 2 0 e3 binding domain LexA_DNA_bind PF01726.16 RLN14351.1 - 0.13 12.1 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 LexA DNA binding domain FGGY_N PF00370.21 RLN14352.1 - 8e-21 74.7 0.2 2.8e-12 46.7 0.0 2.4 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain HTH_23 PF13384.6 RLN14352.1 - 0.00017 21.3 0.1 0.0013 18.5 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain FGGY_C PF02782.16 RLN14352.1 - 0.0012 18.6 0.7 0.0034 17.1 0.7 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain HTH_28 PF13518.6 RLN14352.1 - 0.002 18.2 0.5 0.0086 16.2 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 RLN14352.1 - 0.0098 16.2 0.0 0.026 14.9 0.0 1.7 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 RLN14352.1 - 0.13 12.3 0.2 0.34 11.0 0.2 1.7 1 0 0 1 1 1 0 Winged helix-turn helix MerR PF00376.23 RLN14352.1 - 0.15 11.8 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 MerR family regulatory protein Tim17 PF02466.19 RLN14353.1 - 3.8e-14 53.0 1.7 5e-14 52.6 1.7 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ATG16 PF08614.11 RLN14354.1 - 0.0094 16.2 43.0 0.0094 16.2 43.0 3.7 1 1 3 4 4 4 2 Autophagy protein 16 (ATG16) SpoIISA_toxin PF14171.6 RLN14354.1 - 0.25 11.0 6.1 0.41 10.3 6.1 1.3 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system FliJ PF02050.16 RLN14354.1 - 1.6 9.0 50.5 0.037 14.3 22.5 3.8 2 2 1 3 3 3 0 Flagellar FliJ protein Trypsin_2 PF13365.6 RLN14356.1 - 2.2e-18 67.6 0.1 7.2e-18 65.9 0.1 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 RLN14356.1 - 3.6e-05 23.7 0.1 0.0099 15.7 0.1 2.3 2 0 0 2 2 2 2 Trypsin ACC_epsilon PF13822.6 RLN14357.1 - 0.064 13.9 1.6 0.064 13.9 1.6 3.4 4 0 0 4 4 4 0 Acyl-CoA carboxylase epsilon subunit pKID PF02173.17 RLN14357.1 - 0.14 11.6 1.1 0.31 10.6 1.1 1.5 1 0 0 1 1 1 0 pKID domain Conotoxin PF02950.17 RLN14358.1 - 0.011 16.7 0.0 0.013 16.5 0.0 1.2 1 0 0 1 1 1 0 Conotoxin FIBP PF05427.11 RLN14360.1 - 6e-62 210.0 0.0 4.2e-49 167.8 0.0 2.4 2 1 0 2 2 2 2 Acidic fibroblast growth factor binding (FIBP) SEP PF08059.13 RLN14361.1 - 0.059 13.9 0.0 0.14 12.8 0.0 1.7 1 0 0 1 1 1 0 SEP domain EF-hand_8 PF13833.6 RLN14362.1 - 1.3e-07 31.3 3.8 0.00069 19.4 0.2 4.1 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.32 RLN14362.1 - 8.4e-07 28.1 2.9 8e-05 21.9 0.2 3.6 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 RLN14362.1 - 1.2e-06 28.0 1.1 0.0009 19.0 0.1 4.2 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 RLN14362.1 - 2.1e-06 28.1 0.1 0.013 16.0 0.0 3.9 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN14362.1 - 0.0056 16.1 2.4 0.077 12.5 0.1 3.1 3 0 0 3 3 3 1 EF hand FoP_duplication PF13865.6 RLN14362.1 - 0.14 12.7 1.2 11 6.6 0.9 2.4 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 PH PF00169.29 RLN14363.1 - 8.6e-07 29.4 0.0 1.8e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN14363.1 - 0.032 14.5 0.0 0.072 13.4 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Cpn60_TCP1 PF00118.24 RLN14364.1 - 3.6e-10 39.1 0.0 6.4e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_C50 PF03568.17 RLN14364.1 - 1.5e-05 24.3 0.1 4.5e-05 22.7 0.1 1.8 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.6 RLN14364.1 - 3.6e-05 24.0 1.4 0.087 13.1 0.4 4.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN14364.1 - 0.014 15.5 0.1 0.75 10.1 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat GAT PF03127.14 RLN14364.1 - 0.16 12.3 0.8 4.2 7.8 0.1 3.3 2 0 0 2 2 2 0 GAT domain Abhydrolase_3 PF07859.13 RLN14367.1 - 4.9e-29 101.7 0.0 7.8e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN14367.1 - 5e-09 35.5 0.0 6.6e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 RLN14367.1 - 0.088 12.3 0.0 0.41 10.1 0.0 2.1 2 1 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 RLN14368.1 - 7e-31 107.7 0.0 1.1e-30 107.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN14368.1 - 8.3e-08 31.5 0.0 1.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase PNK3P PF08645.11 RLN14368.1 - 0.026 14.2 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase Peptidase_S9 PF00326.21 RLN14368.1 - 0.052 13.0 0.0 0.58 9.6 0.0 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 RLN14369.1 - 1.8e-28 99.9 0.1 2.9e-28 99.2 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN14369.1 - 1.3e-09 37.4 0.0 1.8e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 RLN14369.1 - 0.015 14.8 0.0 0.057 12.9 0.0 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family FYVE PF01363.21 RLN14370.1 - 0.025 14.7 8.5 0.043 14.0 8.5 1.4 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN14370.1 - 0.23 11.7 5.5 0.47 10.7 5.5 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger CTU2 PF10288.9 RLN14370.1 - 3.2 8.0 7.8 0.48 10.7 2.3 2.2 1 1 1 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 FYVE PF01363.21 RLN14371.1 - 0.036 14.2 10.1 0.059 13.5 10.1 1.3 1 0 0 1 1 1 0 FYVE zinc finger DUF2318 PF10080.9 RLN14371.1 - 0.33 11.1 4.2 0.3 11.2 2.9 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2318) NinF PF05810.12 RLN14371.1 - 2.4 8.1 6.7 20 5.1 0.1 2.3 2 0 0 2 2 2 0 NinF protein CTU2 PF10288.9 RLN14371.1 - 5.3 7.3 7.8 0.7 10.2 1.9 2.2 1 1 1 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 FYVE PF01363.21 RLN14372.1 - 0.079 13.1 7.9 0.15 12.3 7.9 1.4 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN14372.1 - 0.28 11.4 3.9 0.51 10.6 3.9 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Ank_2 PF12796.7 RLN14374.1 - 7.7e-38 129.0 2.4 1.8e-12 47.7 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN14374.1 - 2e-31 108.0 1.5 3e-09 37.2 0.0 4.6 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN14374.1 - 2e-31 107.6 2.8 2.9e-07 30.6 0.1 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 RLN14374.1 - 1.1e-24 85.7 7.6 4.6e-05 23.7 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 RLN14374.1 - 2.7e-23 79.5 0.5 0.014 15.8 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat PK_C PF02887.16 RLN14374.1 - 0.012 15.8 0.1 9.8 6.4 0.0 3.0 3 1 0 3 3 3 0 Pyruvate kinase, alpha/beta domain Cyclin_N PF00134.23 RLN14374.1 - 0.012 15.3 1.2 17 5.2 0.2 4.0 1 1 1 3 3 3 0 Cyclin, N-terminal domain Phosphonate-bd PF12974.7 RLN14374.1 - 0.044 13.4 0.5 4.2 6.9 0.1 2.5 2 1 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein OAM_dimer PF16554.5 RLN14374.1 - 0.093 13.2 0.1 36 4.9 0.0 2.9 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase Anemone_cytotox PF06369.12 RLN14374.1 - 0.12 12.0 0.1 0.36 10.4 0.1 1.8 1 1 0 2 2 2 0 Sea anemone cytotoxic protein Chlorophyllase2 PF12740.7 RLN14374.1 - 0.12 11.3 0.0 14 4.5 0.0 2.4 2 0 0 2 2 2 0 Chlorophyllase enzyme Atu4866 PF11512.8 RLN14374.1 - 0.16 12.3 0.0 36 4.8 0.0 2.4 2 0 0 2 2 2 0 Agrobacterium tumefaciens protein Atu4866 WD40 PF00400.32 RLN14375.1 - 3.6e-25 87.7 11.1 1.8e-06 28.5 0.1 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN14375.1 - 1.2e-09 38.3 0.9 0.037 14.3 0.2 5.3 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN14375.1 - 0.0052 15.8 0.1 5.9 5.7 0.0 3.4 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RLN14375.1 - 0.0065 15.2 0.8 0.022 13.4 0.7 1.8 1 1 1 2 2 2 1 Nucleoporin Nup120/160 HALZ PF02183.18 RLN14375.1 - 0.22 11.7 5.4 5.1 7.4 5.4 2.5 1 1 0 1 1 1 0 Homeobox associated leucine zipper SNO PF01174.19 RLN14377.1 - 1.8e-38 132.3 0.0 2.1e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 RLN14377.1 - 6.2e-09 35.7 0.0 8.3e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 RLN14377.1 - 1.1e-06 28.4 0.1 1.5e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 RLN14377.1 - 0.0011 18.8 0.1 0.0018 18.1 0.1 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family HEAT PF02985.22 RLN14378.1 - 5.6e-19 66.6 26.5 0.0031 17.6 0.0 9.8 10 1 0 10 10 10 6 HEAT repeat HEAT_2 PF13646.6 RLN14378.1 - 1.3e-13 51.2 15.7 0.0026 18.1 0.1 6.2 3 3 1 5 5 5 5 HEAT repeats Vac14_Fab1_bd PF12755.7 RLN14378.1 - 3.8e-10 40.2 0.2 0.019 15.6 0.0 4.6 1 1 1 4 4 4 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 RLN14378.1 - 9.7e-08 32.4 6.1 0.094 13.3 0.0 6.6 7 0 0 7 7 7 2 HEAT-like repeat CLASP_N PF12348.8 RLN14378.1 - 0.00015 21.4 0.4 1.3 8.5 0.0 3.6 1 1 3 4 4 4 2 CLASP N terminal Cnd1 PF12717.7 RLN14378.1 - 0.00024 21.2 0.6 2.9 7.9 0.0 3.5 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Ipi1_N PF12333.8 RLN14378.1 - 0.0062 17.1 0.1 0.049 14.2 0.0 2.3 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation DUF1294 PF06961.13 RLN14378.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) DUF4097 PF13349.6 RLN14390.1 - 7.1e-05 22.3 0.4 0.0026 17.1 0.1 2.9 1 1 0 2 2 2 2 Putative adhesin cNMP_binding PF00027.29 RLN14391.1 - 1.7e-27 95.3 0.1 4.3e-15 55.6 0.0 3.2 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN14391.1 - 7.8e-16 58.0 26.1 8.7e-15 54.6 7.6 2.5 2 0 0 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 RLN14391.1 - 0.74 9.8 6.5 2.2 8.3 0.4 3.5 2 0 0 2 2 2 0 Ion channel Aa_trans PF01490.18 RLN14392.1 - 1.7e-40 139.0 16.3 2.6e-40 138.4 16.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF5383 PF17355.2 RLN14392.1 - 0.58 10.5 0.0 0.58 10.5 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5383) ABC2_membrane_3 PF12698.7 RLN14393.1 - 1.2e-46 159.5 18.1 1.8e-46 158.8 18.1 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 RLN14393.1 - 1.5e-26 93.5 0.0 2.9e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN14393.1 - 7.9e-08 32.4 0.1 4e-06 26.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RLN14393.1 - 0.015 15.0 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF4162 PF13732.6 RLN14393.1 - 0.021 15.5 0.1 3.7 8.3 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4162) CrgA PF06781.12 RLN14393.1 - 0.14 12.3 0.3 0.57 10.3 0.3 2.1 1 0 0 1 1 1 0 Cell division protein CrgA DUF973 PF06157.11 RLN14393.1 - 0.22 10.5 7.2 0.38 9.8 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) ABC2_membrane_2 PF12679.7 RLN14393.1 - 1 8.6 19.7 15 4.7 19.6 2.7 1 1 0 1 1 1 0 ABC-2 family transporter protein Anoctamin PF04547.12 RLN14394.1 - 6.9e-43 147.1 0.0 9.5e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel C2 PF00168.30 RLN14394.1 - 1.8e-05 25.0 0.0 3.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain HisKA_7TM PF16927.5 RLN14394.1 - 0.0094 16.0 5.4 0.014 15.4 0.3 2.5 2 0 0 2 2 2 1 N-terminal 7TM region of histidine kinase MIP PF00230.20 RLN14401.1 - 8.5e-39 133.6 1.9 1e-38 133.3 1.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 RLN14402.1 - 2.7e-08 33.8 0.8 3.2e-08 33.5 0.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein Pkinase PF00069.25 RLN14404.1 - 9.4e-49 166.1 0.0 1.3e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN14404.1 - 2.6e-46 158.0 0.0 3.3e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EphA2_TM PF14575.6 RLN14404.1 - 0.0019 19.0 0.2 0.029 15.3 0.0 2.3 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Haspin_kinase PF12330.8 RLN14404.1 - 0.0034 16.4 0.0 0.073 12.0 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 RLN14404.1 - 0.0057 16.0 0.0 0.0092 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN14404.1 - 0.0094 14.8 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN14404.1 - 0.015 15.3 0.0 0.11 12.4 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Adeno_E3_CR2 PF02439.15 RLN14404.1 - 0.04 13.7 0.3 0.086 12.6 0.3 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM154 PF15102.6 RLN14404.1 - 0.056 13.4 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family UPF0560 PF10577.9 RLN14404.1 - 0.078 11.5 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TMEM52 PF14979.6 RLN14404.1 - 0.14 12.0 2.5 2.3 8.1 2.5 2.3 1 1 0 1 1 1 0 Transmembrane 52 Maf1 PF09174.10 RLN14405.1 - 1.5e-49 168.5 1.0 1.2e-41 142.8 0.0 2.2 2 0 0 2 2 2 2 Maf1 regulator PWI PF01480.17 RLN14405.1 - 0.029 14.7 0.0 0.055 13.8 0.0 1.6 1 1 0 1 1 1 0 PWI domain DUF3972 PF13118.6 RLN14406.1 - 0.91 10.0 5.3 0.25 11.8 0.3 2.5 2 1 0 3 3 3 0 Protein of unknown function (DUF3972) Pkinase PF00069.25 RLN14407.1 - 1.9e-61 207.7 0.1 2e-59 201.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN14407.1 - 7.5e-27 94.2 0.4 4e-26 91.9 0.4 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN14407.1 - 0.00015 21.2 0.3 0.00029 20.3 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN14407.1 - 0.0054 16.1 0.2 0.048 13.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RLN14407.1 - 0.029 13.1 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 RLN14407.1 - 0.13 11.2 0.0 0.92 8.4 0.0 1.9 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 RLN14407.1 - 0.13 11.2 0.2 0.19 10.6 0.2 1.1 1 0 0 1 1 1 0 Haspin like kinase domain TPR_12 PF13424.6 RLN14409.1 - 9.3e-08 32.3 9.1 0.12 12.7 0.2 3.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 RLN14409.1 - 3.8e-06 26.6 5.6 0.0044 16.8 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN14409.1 - 0.00011 22.2 3.2 0.71 10.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN14409.1 - 0.00012 22.0 9.2 0.037 14.1 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN14409.1 - 0.0051 16.8 6.7 1.3 9.2 0.1 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN14409.1 - 0.015 16.1 6.4 0.73 10.8 0.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN14409.1 - 0.017 15.0 3.4 0.49 10.3 0.9 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat eIF-3c_N PF05470.12 RLN14409.1 - 0.045 12.1 0.8 0.051 11.9 0.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus TPR_16 PF13432.6 RLN14409.1 - 1.1 10.0 8.5 2.9 8.6 0.5 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_pol_phi PF04931.13 RLN14409.1 - 3.6 5.6 8.3 3.9 5.5 8.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-F_N PF10481.9 RLN14429.1 - 0.02 14.6 0.9 0.02 14.6 0.9 2.4 2 0 0 2 2 2 0 Cenp-F N-terminal domain Rep-A_N PF04057.12 RLN14429.1 - 0.16 12.0 0.5 1.6 8.8 0.1 2.2 2 0 0 2 2 2 0 Replication factor-A protein 1, N-terminal domain APC_N_CC PF16689.5 RLN14429.1 - 0.67 10.1 4.0 3.7 7.7 0.2 2.9 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain ZapB PF06005.12 RLN14429.1 - 0.94 10.0 7.2 4.4 7.8 7.2 2.2 1 1 0 1 1 1 0 Cell division protein ZapB SNF2_N PF00176.23 RLN14430.1 - 5.9e-57 193.0 0.3 8.9e-56 189.1 0.3 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN14430.1 - 3.5e-10 40.2 0.0 7.6e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN14430.1 - 0.0073 16.3 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cyclin_N PF00134.23 RLN14431.1 - 3.1e-23 81.9 0.2 3.1e-23 81.9 0.2 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Xin PF08043.12 RLN14431.1 - 0.15 11.7 0.9 0.33 10.7 0.9 1.6 1 0 0 1 1 1 0 Xin repeat PI3_PI4_kinase PF00454.27 RLN14432.1 - 4.9e-31 108.4 0.0 7.2e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Helicase_C_3 PF13625.6 RLN14432.1 - 0.17 12.0 0.7 1.7 8.8 0.0 2.5 3 0 0 3 3 3 0 Helicase conserved C-terminal domain Peptidase_M28 PF04389.17 RLN14433.1 - 8.2e-10 38.7 0.0 1.6e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.15 RLN14433.1 - 2.4e-07 30.9 0.0 7.4e-06 26.1 0.0 2.8 2 1 1 3 3 3 1 Transferrin receptor-like dimerisation domain Phage_tail_X PF05489.12 RLN14433.1 - 0.013 15.2 0.1 0.025 14.2 0.1 1.5 1 0 0 1 1 1 0 Phage Tail Protein X Nicastrin PF05450.15 RLN14433.1 - 0.013 14.9 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 Nicastrin PA PF02225.22 RLN14433.1 - 0.023 14.7 0.2 0.067 13.2 0.2 1.8 1 0 0 1 1 1 0 PA domain RyR PF02026.16 RLN14434.1 - 9e-61 202.1 0.2 8.7e-31 106.0 0.0 2.9 3 0 0 3 3 3 2 RyR domain PKD_channel PF08016.12 RLN14434.1 - 3.4e-36 124.8 13.4 2.3e-29 102.4 14.3 2.1 2 0 0 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 RLN14434.1 - 7.4e-12 45.0 15.3 1.1e-11 44.5 15.3 1.2 1 0 0 1 1 1 1 Ion transport protein His_Phos_2 PF00328.22 RLN14436.1 - 2.6e-08 33.6 0.2 7.5e-06 25.5 0.2 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) tRNA_SAD PF07973.14 RLN14437.1 - 1.9e-06 27.9 0.0 5.6e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 RLN14437.1 - 5.3e-05 21.9 0.0 8e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) Matrilin_ccoil PF10393.9 RLN14437.1 - 1.8 8.5 5.6 1.7 8.5 0.8 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin FlxA PF14282.6 RLN14438.1 - 0.025 14.6 0.8 0.025 14.6 0.8 3.1 3 1 0 3 3 3 0 FlxA-like protein NAM-associated PF14303.6 RLN14438.1 - 7.2 7.3 23.1 0.18 12.5 8.0 2.4 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain WD40 PF00400.32 RLN14439.1 - 1.3e-11 44.9 13.3 0.093 13.6 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Sec16_C PF12931.7 RLN14439.1 - 8.2e-09 35.5 0.3 6.8e-08 32.5 0.3 2.1 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 ANAPC4_WD40 PF12894.7 RLN14439.1 - 1.9e-06 28.1 0.0 0.14 12.5 0.1 3.7 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Prp18 PF02840.15 RLN14439.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Prp18 domain BBS2_C PF14782.6 RLN14440.1 - 1.2e-107 360.4 0.0 6.2e-106 354.7 0.0 2.4 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 RLN14440.1 - 6.9e-44 148.3 0.0 5e-41 139.1 0.0 2.8 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 RLN14440.1 - 3.5e-38 129.7 0.0 1.9e-37 127.3 0.0 2.3 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, N-terminal Itfg2 PF15907.5 RLN14440.1 - 1.8e-08 33.8 0.4 0.13 11.3 0.0 4.1 2 1 1 4 4 4 3 Integrin-alpha FG-GAP repeat-containing protein 2 VCBS PF13517.6 RLN14440.1 - 0.0021 18.6 0.0 0.7 10.5 0.1 3.5 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 RLN14440.1 - 0.11 12.7 0.2 0.62 10.2 0.0 2.5 2 0 0 2 2 2 0 FG-GAP repeat BBS2_C PF14782.6 RLN14441.1 - 2.9e-33 115.3 2.0 3.2e-33 115.2 2.0 1.0 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal Dynactin_p22 PF07426.11 RLN14441.1 - 0.026 14.4 0.0 0.026 14.4 0.0 1.1 1 0 0 1 1 1 0 Dynactin subunit p22 Phytoreo_S7 PF07236.11 RLN14441.1 - 0.041 12.3 0.1 0.046 12.1 0.1 1.0 1 0 0 1 1 1 0 Phytoreovirus S7 protein Rhodanese PF00581.20 RLN14442.1 - 5.9e-10 39.6 0.0 6.6e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Phage_TAC_6 PF09550.10 RLN14442.1 - 0.035 14.5 0.6 5.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC PTPlike_phytase PF14566.6 RLN14442.1 - 0.057 13.5 0.0 0.091 12.9 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate LEH PF07858.12 RLN14442.1 - 0.059 13.5 0.0 0.081 13.0 0.0 1.2 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain Ham1p_like PF01725.16 RLN14443.1 - 1.1e-53 181.9 0.0 1.3e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DUF5621 PF18532.1 RLN14443.1 - 0.19 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5621) COG4 PF08318.12 RLN14444.1 - 8.2e-31 107.3 0.0 1.5e-30 106.5 0.0 1.4 1 0 0 1 1 1 1 COG4 transport protein Vps53_N PF04100.12 RLN14444.1 - 0.00042 19.4 1.6 0.0013 17.8 0.7 2.0 2 0 0 2 2 2 1 Vps53-like, N-terminal Sec15 PF04091.12 RLN14444.1 - 0.00049 19.6 0.0 0.0091 15.4 0.0 2.8 3 0 0 3 3 3 1 Exocyst complex subunit Sec15-like SesA PF17107.5 RLN14444.1 - 0.021 15.0 1.7 12 6.1 0.1 3.7 3 1 1 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Metallophos PF00149.28 RLN14445.1 - 6.3e-35 121.5 1.0 1e-34 120.9 1.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 RLN14445.1 - 1.9e-26 92.1 0.0 4.1e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 RLN14445.1 - 7.4e-14 50.9 1.4 7.6e-05 22.4 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN14445.1 - 2.5e-12 45.9 1.7 0.0015 18.5 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN14445.1 - 4.3e-08 32.8 0.8 0.00018 21.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN14445.1 - 4.6e-06 27.2 3.8 1.8e-05 25.3 0.6 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN14445.1 - 6.9e-06 25.6 2.8 0.0027 17.3 0.2 3.2 1 1 2 3 3 3 2 TPR repeat TPR_9 PF13371.6 RLN14445.1 - 3.3e-05 23.9 0.4 0.00013 22.1 0.4 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN14445.1 - 0.0088 16.4 0.2 0.045 14.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN14445.1 - 0.013 16.3 3.6 0.13 13.1 0.1 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 RLN14445.1 - 0.016 15.2 0.1 6.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN14445.1 - 0.017 15.6 1.8 0.12 12.9 0.3 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.17 RLN14445.1 - 0.032 14.7 0.4 0.071 13.5 0.4 1.5 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_12 PF13424.6 RLN14445.1 - 0.059 13.7 2.7 1 9.7 0.3 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF2451 PF10474.9 RLN14446.1 - 7.6e-53 179.7 0.0 1.7e-52 178.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 RLN14446.1 - 0.00061 19.2 5.3 0.011 15.1 0.3 2.9 2 1 1 3 3 3 2 Vacuolar-sorting protein 54, of GARP complex HORMA PF02301.18 RLN14446.1 - 0.19 11.3 1.3 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 HORMA domain PX PF00787.24 RLN14447.1 - 1.3e-06 28.4 0.1 2.6e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 PX domain TetR_C_28 PF17937.1 RLN14447.1 - 0.1 13.0 0.3 6.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SpoIIIAH PF12685.7 RLN14447.1 - 0.2 11.4 2.4 0.31 10.8 2.4 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Histone PF00125.24 RLN14448.1 - 9.9e-19 68.0 0.1 1.2e-18 67.8 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 RLN14448.1 - 0.00022 21.7 0.0 0.00036 21.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 RLN14448.1 - 0.0099 16.1 0.1 0.029 14.6 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 RLN14448.1 - 0.068 13.2 0.1 0.077 13.0 0.1 1.2 1 0 0 1 1 1 0 YscO-like protein His_Phos_2 PF00328.22 RLN14449.1 - 3.7e-41 141.8 0.0 5.6e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 RLN14449.1 - 9.5e-38 128.3 0.0 1.8e-37 127.3 0.0 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 RLN14449.1 - 0.00018 21.2 0.0 0.0034 17.0 0.0 2.2 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 RLN14449.1 - 0.12 12.4 0.0 0.78 9.8 0.0 2.2 1 1 0 1 1 1 0 ATP-grasp domain HEAT PF02985.22 RLN14450.1 - 0.037 14.3 0.6 26 5.4 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat Fez1 PF06818.15 RLN14450.1 - 0.69 10.3 59.1 0.9 10.0 4.8 3.5 1 1 2 3 3 3 0 Fez1 Aminotran_1_2 PF00155.21 RLN14451.1 - 4.9e-38 131.2 0.0 6.5e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 RLN14451.1 - 0.023 14.0 0.0 0.075 12.3 0.0 1.9 1 1 0 1 1 1 0 Beta-eliminating lyase PFK PF00365.20 RLN14452.1 - 2.6e-60 204.2 0.2 3.4e-60 203.8 0.2 1.1 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 RLN14452.1 - 0.0023 17.5 0.0 0.0062 16.1 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 RLN14452.1 - 0.06 12.5 0.0 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 ATP-NAD kinase Amidohydro_1 PF01979.20 RLN14453.1 - 9.2e-73 245.5 1.3 1.3e-72 245.0 1.3 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 RLN14453.1 - 7.5e-20 71.8 4.6 6.3e-18 65.5 0.3 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 RLN14453.1 - 0.0055 16.1 0.0 0.0087 15.4 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase PTCB-BRCT PF12738.7 RLN14454.1 - 3.1e-17 62.3 1.0 9.6e-11 41.5 0.0 5.1 5 0 0 5 5 5 2 twin BRCT domain BRCT PF00533.26 RLN14454.1 - 1.4e-15 57.4 0.0 0.00011 22.5 0.0 6.9 7 0 0 7 7 7 5 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 RLN14454.1 - 6.2e-15 55.4 0.0 0.016 15.6 0.0 6.6 6 1 0 6 6 6 4 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 RLN14454.1 - 4.6e-09 36.1 0.0 7.7e-08 32.1 0.0 2.9 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 RLN14454.1 - 5.9e-08 32.9 0.0 1.8 8.9 0.0 5.5 5 0 0 5 5 5 3 DNA ligase 3 BRCT domain Chromo PF00385.24 RLN14456.1 - 1.1e-05 25.2 0.7 2.1e-05 24.3 0.7 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain YhhN PF07947.14 RLN14456.1 - 0.0096 15.5 4.5 0.016 14.9 4.5 1.3 1 0 0 1 1 1 1 YhhN family UPF0128 PF03673.13 RLN14456.1 - 0.075 12.5 1.1 0.12 11.8 1.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) SOG2 PF10428.9 RLN14456.1 - 0.29 10.3 16.8 0.47 9.6 16.8 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Cullin PF00888.22 RLN14457.1 - 7.3e-173 576.5 4.5 9.2e-173 576.2 4.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 RLN14457.1 - 2.2e-18 66.1 2.8 2.2e-18 66.1 2.8 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain eIF-6 PF01912.18 RLN14457.1 - 0.13 11.6 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 eIF-6 family Nucleoporin_C PF03177.14 RLN14458.1 - 1.4e-08 34.0 2.9 1.4e-06 27.4 3.3 2.7 1 1 1 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal Myosin_head PF00063.21 RLN14460.1 - 4.2e-125 418.5 0.2 6.1e-125 418.0 0.2 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 RLN14460.1 - 7.1e-27 94.0 0.0 2.3e-26 92.4 0.0 2.0 1 0 0 1 1 1 1 MyTH4 domain FERM_M PF00373.18 RLN14460.1 - 1.5e-07 31.8 0.0 4.4e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 FERM central domain Virulence_fact PF13769.6 RLN14460.1 - 0.045 14.0 0.1 0.16 12.2 0.1 2.0 1 0 0 1 1 1 0 Virulence factor PatG_D PF18047.1 RLN14460.1 - 0.083 13.3 0.1 4 7.9 0.0 3.0 3 0 0 3 3 3 0 PatG Domain Thioredoxin PF00085.20 RLN14461.1 - 7.6e-26 90.1 0.5 8.4e-26 90.0 0.5 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 RLN14461.1 - 1.9e-05 25.1 0.2 8e-05 23.0 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RLN14461.1 - 6.7e-05 23.1 0.1 0.00015 22.1 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 RLN14461.1 - 0.00037 20.3 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 RLN14461.1 - 0.00088 19.2 0.1 0.001 19.0 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Phosducin PF02114.16 RLN14461.1 - 0.0027 16.7 0.1 0.0027 16.7 0.1 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin_4 PF13462.6 RLN14461.1 - 0.0079 16.4 0.1 1.3 9.1 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin Redoxin PF08534.10 RLN14461.1 - 0.061 13.0 0.1 0.067 12.9 0.1 1.2 1 0 0 1 1 1 0 Redoxin Glutaredoxin PF00462.24 RLN14461.1 - 0.068 13.4 0.8 0.21 11.8 0.8 1.9 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_3 PF13192.6 RLN14461.1 - 0.086 12.9 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin domain Ank_2 PF12796.7 RLN14462.1 - 1.1e-88 291.9 20.6 1.4e-16 60.8 0.2 5.9 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN14462.1 - 1.9e-52 174.9 8.7 3.7e-10 40.1 0.1 6.7 6 1 2 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN14462.1 - 4.7e-47 152.5 8.7 5.8e-05 23.2 0.0 10.7 11 0 0 11 11 11 9 Ankyrin repeat Ank PF00023.30 RLN14462.1 - 4.7e-42 140.6 12.4 1.3e-05 25.4 0.0 10.7 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 RLN14462.1 - 2.1e-41 139.4 14.0 6.4e-06 26.4 0.2 9.3 4 2 6 10 10 10 8 Ankyrin repeats (many copies) Phage_int_SAM_5 PF13102.6 RLN14463.1 - 0.00087 19.6 0.1 0.0015 18.9 0.1 1.3 1 0 0 1 1 1 1 Phage integrase SAM-like domain FAM150 PF15129.6 RLN14463.1 - 0.091 12.9 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 FAM150 family AMP-binding PF00501.28 RLN14464.1 - 6.1e-94 315.0 0.2 7.4e-94 314.7 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN14464.1 - 1.9e-23 83.2 0.4 4.1e-23 82.2 0.4 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 RLN14464.1 - 9.5e-19 67.1 0.1 2e-18 66.0 0.1 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus ALMS_motif PF15309.6 RLN14465.1 - 2.2e-08 34.7 21.6 2.2e-08 34.7 21.6 5.0 4 1 0 5 5 5 1 ALMS motif COX16 PF14138.6 RLN14465.1 - 2.7e-07 31.0 0.0 2.7e-07 31.0 0.0 6.6 6 2 0 6 6 6 1 Cytochrome c oxidase assembly protein COX16 DBP10CT PF08147.12 RLN14465.1 - 0.016 15.4 0.1 0.089 13.1 0.1 2.3 1 0 0 1 1 1 0 DBP10CT (NUC160) domain AMP-binding PF00501.28 RLN14466.1 - 4.2e-92 308.9 0.0 5.3e-92 308.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN14466.1 - 6.7e-23 81.5 0.2 1.7e-22 80.2 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 RLN14466.1 - 2.9e-19 68.7 0.4 6e-19 67.7 0.4 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF4262 PF14081.6 RLN14466.1 - 0.049 13.8 0.0 24 5.2 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4262) AMP-binding PF00501.28 RLN14467.1 - 7.3e-91 304.9 0.1 9e-91 304.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN14467.1 - 1.1e-23 84.0 0.8 2.7e-23 82.8 0.8 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 RLN14467.1 - 1.3e-19 69.8 0.3 2.8e-19 68.7 0.3 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF1967 PF09269.11 RLN14467.1 - 0.069 13.1 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) TTC5_OB PF16669.5 RLN14467.1 - 0.14 11.8 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain SIR2 PF02146.17 RLN14468.1 - 8e-29 100.8 0.0 1.4e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 Sir2 family cIII PF08134.11 RLN14468.1 - 0.021 14.6 0.1 0.058 13.1 0.1 1.7 1 0 0 1 1 1 0 cIII protein family Mito_carr PF00153.27 RLN14469.1 - 7.6e-30 102.7 12.1 4.9e-18 64.8 0.2 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein SatD PF16264.5 RLN14469.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 SatD family (SatD) Ribosomal_S5 PF00333.20 RLN14470.1 - 6.6e-17 61.3 0.0 1.4e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Peptidase_M24 PF00557.24 RLN14471.1 - 8.4e-34 117.1 0.1 1.1e-33 116.8 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 KASH_CCD PF14662.6 RLN14471.1 - 0.14 12.0 0.0 0.14 12.0 0.0 1.5 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH RNA_polI_A34 PF08208.11 RLN14471.1 - 0.8 9.8 11.0 1.4 9.0 11.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Mucin PF01456.17 RLN14473.1 - 0.18 11.8 17.6 0.24 11.4 17.6 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein AJAP1_PANP_C PF15298.6 RLN14473.1 - 0.53 10.5 8.9 0.7 10.1 8.9 1.1 1 0 0 1 1 1 0 AJAP1/PANP C-terminus ORC6 PF05460.13 RLN14476.1 - 7.7 5.7 10.4 0.64 9.2 4.9 1.7 1 1 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) DUF900 PF05990.12 RLN14483.1 - 4e-08 33.1 0.0 1.2e-05 24.9 0.0 2.7 2 1 1 3 3 3 2 Alpha/beta hydrolase of unknown function (DUF900) WD40 PF00400.32 RLN14484.1 - 2.2e-06 28.3 8.0 0.0029 18.4 0.3 5.6 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN14484.1 - 0.0042 17.3 0.7 1.9 8.8 0.0 3.9 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PX PF00787.24 RLN14485.1 - 3.4e-05 23.8 0.0 4.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 PX domain PSRT PF07636.11 RLN14486.1 - 0.49 10.1 2.8 0.39 10.4 0.6 1.9 2 0 0 2 2 2 0 PSRT AAA PF00004.29 RLN14487.1 - 6.4e-18 65.5 0.0 2.8e-17 63.4 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN14487.1 - 7.4e-07 29.7 0.3 9.5e-06 26.1 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 RLN14487.1 - 4e-06 26.9 0.0 1.2e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RLN14487.1 - 0.00062 20.0 0.0 0.0022 18.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 RLN14487.1 - 0.0018 17.5 0.0 0.0037 16.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 RLN14487.1 - 0.0032 17.6 0.0 0.035 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 RLN14487.1 - 0.0046 17.2 0.1 0.1 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 RLN14487.1 - 0.0062 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 RLN14487.1 - 0.0069 16.2 0.3 0.015 15.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RLN14487.1 - 0.013 15.3 0.1 0.029 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 RLN14487.1 - 0.02 14.8 1.0 0.69 9.8 0.3 2.4 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.6 RLN14487.1 - 0.071 13.4 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RLN14487.1 - 0.079 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 RLN14487.1 - 0.08 13.5 0.0 0.32 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RLN14487.1 - 0.084 13.3 0.0 0.25 11.8 0.0 1.9 2 0 0 2 2 1 0 RNA helicase MCM PF00493.23 RLN14487.1 - 0.085 11.9 0.0 0.27 10.3 0.0 1.8 2 0 0 2 2 2 0 MCM P-loop domain Bac_DnaA PF00308.18 RLN14487.1 - 0.085 12.7 0.0 0.43 10.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_7 PF12775.7 RLN14487.1 - 0.088 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 RLN14487.1 - 0.093 13.2 0.0 0.3 11.6 0.0 1.9 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 RLN14487.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 RLN14487.1 - 0.16 11.7 0.1 0.7 9.6 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 RLN14488.1 - 4.5e-16 59.5 0.0 3.6e-08 33.9 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RLN14488.1 - 0.00024 21.1 0.0 0.00063 19.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RLN14488.1 - 0.00071 20.0 0.0 0.0019 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 RLN14488.1 - 0.0041 17.7 0.0 0.0093 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 RLN14488.1 - 0.0087 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 RLN14488.1 - 0.013 15.8 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 RLN14488.1 - 0.019 14.7 0.3 0.11 12.3 0.0 2.2 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 RLN14488.1 - 0.041 14.2 0.1 0.1 12.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RLN14488.1 - 0.05 13.1 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 RLN14488.1 - 0.051 13.3 0.4 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RLN14488.1 - 0.058 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 RLN14488.1 - 0.058 13.2 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 RLN14488.1 - 0.058 13.8 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 RLN14488.1 - 0.097 12.8 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RLN14488.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Radial_spoke_3 PF06098.11 RLN14489.1 - 8.2e-100 333.8 7.7 9.9e-100 333.5 7.7 1.1 1 0 0 1 1 1 1 Radial spoke protein 3 DUF444 PF04285.12 RLN14489.1 - 0.041 13.0 3.7 0.016 14.3 1.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF444) HLH PF00010.26 RLN14490.1 - 1.1e-08 34.9 1.5 1.8e-08 34.2 1.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1265 PF06887.14 RLN14490.1 - 0.31 11.0 1.2 2.1 8.4 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1265) TnpV PF14198.6 RLN14491.1 - 4.1 7.4 6.7 4.3 7.4 1.3 2.6 1 1 1 2 2 2 0 Transposon-encoded protein TnpV AAA PF00004.29 RLN14494.1 - 3.5e-17 63.1 0.1 1.3e-15 58.0 0.0 2.8 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN14494.1 - 3.1e-06 27.7 0.0 8.8e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 RLN14494.1 - 5.2e-05 23.3 0.0 0.00014 21.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 RLN14494.1 - 0.00073 18.8 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 RLN14494.1 - 0.0017 18.5 0.1 0.015 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RLN14494.1 - 0.0019 18.5 0.1 0.0053 17.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 RLN14494.1 - 0.0029 17.4 0.1 0.0057 16.4 0.1 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 RLN14494.1 - 0.011 15.6 0.1 0.024 14.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RLN14494.1 - 0.013 15.8 0.0 0.057 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RLN14494.1 - 0.013 16.0 0.1 0.058 13.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 RLN14494.1 - 0.016 14.9 0.1 0.031 14.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RLN14494.1 - 0.019 15.5 0.0 0.081 13.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 RLN14494.1 - 0.024 15.0 0.1 0.07 13.5 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_19 PF13245.6 RLN14494.1 - 0.045 14.1 0.3 0.1 12.9 0.3 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RLN14494.1 - 0.07 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 RLN14494.1 - 0.072 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 RLN14494.1 - 0.084 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 RLN14494.1 - 0.092 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 RLN14494.1 - 0.097 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.18 RLN14494.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 RLN14494.1 - 0.14 11.7 0.1 0.34 10.5 0.1 1.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 RLN14494.1 - 0.16 11.8 0.6 0.96 9.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.29 RLN14495.1 - 1.9e-18 67.2 0.1 3.4e-10 40.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN14495.1 - 3.7e-07 30.7 0.0 9.5e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 RLN14495.1 - 9.6e-06 25.6 0.1 6.2e-05 23.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RLN14495.1 - 0.00087 19.6 0.1 0.0076 16.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 RLN14495.1 - 0.0012 18.1 0.0 0.0022 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 RLN14495.1 - 0.0072 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RLN14495.1 - 0.0076 16.4 0.0 0.022 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RLN14495.1 - 0.0093 15.8 1.0 0.026 14.3 0.1 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RLN14495.1 - 0.016 14.5 0.2 0.26 10.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 RLN14495.1 - 0.025 14.3 0.1 0.054 13.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RLN14495.1 - 0.031 14.8 0.1 0.48 11.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_6 PF12774.7 RLN14495.1 - 0.034 13.1 0.4 0.34 9.8 0.0 2.1 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region IstB_IS21 PF01695.17 RLN14495.1 - 0.037 13.7 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 RLN14495.1 - 0.039 14.3 0.8 0.3 11.4 0.1 2.5 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 RLN14495.1 - 0.053 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 RLN14495.1 - 0.055 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 RLN14495.1 - 0.061 13.8 0.0 0.21 12.1 0.0 1.9 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 RLN14495.1 - 0.065 13.6 0.1 0.21 12.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_7 PF12775.7 RLN14495.1 - 0.075 12.5 0.1 0.2 11.1 0.1 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 RLN14495.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 RLN14495.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Herpes_UL92 PF03048.14 RLN14495.1 - 0.33 10.7 1.5 0.55 10.0 0.1 1.9 2 0 0 2 2 2 0 UL92 family Ysc84 PF04366.12 RLN14496.1 - 9.7e-20 70.6 0.0 1.3e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator Galactosyl_T PF01762.21 RLN14500.1 - 5.8e-23 81.7 0.0 9e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase UCH PF00443.29 RLN14501.1 - 1e-31 110.4 0.0 1.6e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Galactosyl_T PF01762.21 RLN14501.1 - 9.2e-27 94.1 0.0 1.5e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Glyco_transf_10 PF00852.19 RLN14501.1 - 1.4e-17 63.9 0.0 3e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term UCH_1 PF13423.6 RLN14501.1 - 1.3e-05 25.0 0.0 2.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MAGI_u5 PF16666.5 RLN14501.1 - 0.11 12.7 0.4 0.89 9.7 0.1 2.2 1 1 1 2 2 2 0 Unstructured region on MAGI Fringe PF02434.16 RLN14501.1 - 0.17 11.3 0.1 0.47 9.8 0.1 1.7 1 1 0 1 1 1 0 Fringe-like Acetyltransf_1 PF00583.25 RLN14504.1 - 1.1e-05 25.7 0.2 2.3e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RLN14504.1 - 1.9e-05 24.6 0.1 3.8e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN14504.1 - 0.0071 16.7 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 RLN14504.1 - 0.0081 16.3 0.2 0.017 15.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain D123 PF07065.14 RLN14504.1 - 0.066 12.4 0.1 0.094 11.8 0.1 1.1 1 0 0 1 1 1 0 D123 CDP-OH_P_transf PF01066.21 RLN14507.1 - 9.9e-13 48.7 1.9 9.9e-13 48.7 1.9 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Peptidase_C65 PF10275.9 RLN14508.1 - 2.5e-18 66.4 0.0 2.9e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain Methyltransf_16 PF10294.9 RLN14509.1 - 1.5e-19 70.4 0.0 7.9e-13 48.5 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase zf-MYND PF01753.18 RLN14509.1 - 2.7e-11 43.3 10.9 7e-11 42.0 10.9 1.8 1 1 0 1 1 1 1 MYND finger Ank_2 PF12796.7 RLN14509.1 - 0.00025 21.6 0.1 0.001 19.6 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 RLN14509.1 - 0.00049 20.4 0.1 0.0034 17.8 0.0 2.4 3 0 0 3 3 2 1 Ankyrin repeat zf-C6H2 PF15801.5 RLN14509.1 - 0.0032 17.7 3.4 0.0084 16.4 3.4 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding Met_10 PF02475.16 RLN14509.1 - 0.0037 17.0 0.0 0.0073 16.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 RLN14509.1 - 0.0085 15.9 0.1 0.021 14.6 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN14509.1 - 0.016 14.8 0.0 0.051 13.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase small domain TFIIE_alpha PF02002.17 RLN14509.1 - 0.022 14.6 0.1 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 TFIIE alpha subunit Ank_3 PF13606.6 RLN14509.1 - 0.027 15.0 0.0 0.24 12.1 0.0 2.6 3 0 0 3 3 2 0 Ankyrin repeat PrmA PF06325.13 RLN14509.1 - 0.03 13.7 0.2 0.095 12.1 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Ank_4 PF13637.6 RLN14509.1 - 0.05 14.2 0.0 2.4 8.8 0.0 2.6 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Smoothelin PF12510.8 RLN14509.1 - 0.85 9.7 9.1 3.7 7.7 0.2 3.2 3 0 0 3 3 3 0 Smoothelin cytoskeleton protein DHHC PF01529.20 RLN14510.1 - 2.7e-21 76.1 12.9 2.7e-21 76.1 12.9 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase PAS PF00989.25 RLN14510.1 - 0.043 13.8 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 PAS fold MIP PF00230.20 RLN14511.1 - 6.9e-48 163.3 11.7 8.8e-48 163.0 11.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein ketoacyl-synt PF00109.26 RLN14511.1 - 0.029 13.9 0.1 0.075 12.6 0.1 1.6 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Peptidase_C65 PF10275.9 RLN14513.1 - 1.2e-21 77.3 0.0 1.3e-21 77.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain Peptidase_C101 PF16218.5 RLN14513.1 - 0.025 13.8 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C101 DUF2373 PF10180.9 RLN14513.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) DUF5500 PF17604.2 RLN14514.1 - 0.081 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5500) RasGAP PF00616.19 RLN14514.1 - 0.092 12.4 0.0 0.59 9.8 0.0 2.0 1 1 1 2 2 2 0 GTPase-activator protein for Ras-like GTPase AAA_13 PF13166.6 RLN14584.1 - 4.6 5.8 8.7 7.3 5.1 8.7 1.2 1 0 0 1 1 1 0 AAA domain TEX13 PF15186.6 RLN14584.1 - 8.4 6.1 15.8 1.7 8.3 0.7 2.9 3 0 0 3 3 3 0 Testis-expressed sequence 13 protein family Ins145_P3_rec PF08709.11 RLN14585.1 - 1.4e-05 24.4 0.0 0.00038 19.7 0.0 2.1 1 1 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor CopK PF11525.8 RLN14588.1 - 0.22 11.2 0.1 0.42 10.3 0.0 1.5 2 0 0 2 2 2 0 Copper resistance protein K 4HBT PF03061.22 RLN14589.1 - 8.6e-08 32.4 0.0 1.4e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF3828 PF12883.7 RLN14590.1 - 0.0088 16.4 0.1 0.011 16.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3828) 4HBT PF03061.22 RLN14591.1 - 1e-14 54.6 0.2 6.1e-08 32.9 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily DUF724 PF05266.14 RLN14592.1 - 0.0026 17.6 12.1 0.0026 17.6 12.1 5.2 2 2 4 6 6 6 2 Protein of unknown function (DUF724) HOOK PF05622.12 RLN14592.1 - 0.19 9.9 59.2 0.033 12.3 23.2 3.8 2 1 0 3 3 3 0 HOOK protein MitMem_reg PF13012.6 RLN14592.1 - 0.82 10.1 7.7 0.22 12.0 1.6 3.0 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF465 PF04325.13 RLN14592.1 - 7 6.8 13.4 0.15 12.2 2.9 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF465) MDMPI_N PF11716.8 RLN14601.1 - 0.0042 17.8 8.9 3 8.5 0.9 4.6 3 1 2 5 5 5 1 Mycothiol maleylpyruvate isomerase N-terminal domain STIL_N PF15253.6 RLN14601.1 - 0.069 12.1 0.0 6.5 5.6 0.0 2.2 2 0 0 2 2 2 0 SCL-interrupting locus protein N-terminus Enkurin PF13864.6 RLN14601.1 - 0.13 12.7 7.3 3 8.3 1.5 3.0 2 0 0 2 2 2 0 Calmodulin-binding Flg_new PF09479.10 RLN14601.1 - 0.16 12.1 3.0 15 5.9 0.2 2.6 2 0 0 2 2 2 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) SDF PF00375.18 RLN14602.1 - 4.1e-101 338.8 29.8 4.7e-101 338.6 29.8 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF1324 PF07038.11 RLN14602.1 - 0.15 12.3 0.3 3.6 7.9 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1324) SSP160 PF06933.11 RLN14603.1 - 1.5 7.0 3.0 2 6.5 3.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Enkurin PF13864.6 RLN14603.1 - 1.9 9.0 5.3 0.98 9.9 1.6 2.4 2 1 0 2 2 2 0 Calmodulin-binding NCA2 PF08637.10 RLN14604.1 - 1.7e-08 34.0 0.0 3.3e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 CLZ PF16526.5 RLN14604.1 - 0.11 12.9 0.6 0.33 11.3 0.3 2.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Arm PF00514.23 RLN14608.1 - 9.3e-30 101.7 9.2 8.6e-06 25.6 0.0 7.3 7 1 0 7 7 7 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN14608.1 - 2.3e-13 50.3 14.7 0.00026 21.4 0.1 5.4 3 2 3 6 6 6 6 HEAT-like repeat HEAT PF02985.22 RLN14608.1 - 4.6e-09 35.8 5.7 3.6 8.1 0.1 6.2 6 0 0 6 6 6 3 HEAT repeat TM1506 PF08973.10 RLN14608.1 - 7.5e-06 25.6 0.0 12 5.6 0.0 5.0 2 1 3 5 5 5 1 Domain of unknown function (DUF1893) HEAT_2 PF13646.6 RLN14608.1 - 0.00014 22.2 18.0 0.0011 19.3 2.5 4.1 1 1 2 4 4 4 3 HEAT repeats NFACT-R_2 PF18297.1 RLN14608.1 - 0.00015 21.9 0.3 23 5.2 0.0 5.0 1 1 4 5 5 5 0 NFACT protein RNA binding domain DDE_Tnp_IS66_C PF13817.6 RLN14608.1 - 0.00088 19.4 0.0 65 3.9 0.0 5.3 7 0 0 7 7 7 0 IS66 C-terminal element PfaD_N PF18328.1 RLN14608.1 - 0.0063 16.4 1.8 1.6e+02 2.3 0.0 5.0 5 0 0 5 5 5 0 Fatty acid synthase subunit PfaD N-terminal domain DUF294_C PF10335.9 RLN14608.1 - 0.029 14.2 4.0 8.9 6.1 0.1 4.4 2 1 3 5 5 5 0 Putative nucleotidyltransferase substrate binding domain HEAT_PBS PF03130.16 RLN14608.1 - 0.072 13.8 24.6 6 7.8 0.3 6.7 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat GH97_C PF14509.6 RLN14608.1 - 0.2 11.9 1.0 2e+02 2.3 0.0 4.3 3 2 1 4 4 4 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation DUF555 PF04475.12 RLN14608.1 - 3.8 7.9 5.6 1.2e+02 3.1 0.0 4.4 4 1 1 5 5 5 0 Protein of unknown function (DUF555) MIF4G PF02854.19 RLN14639.1 - 5.3e-08 32.8 0.0 6e-08 32.6 0.0 1.0 1 0 0 1 1 1 1 MIF4G domain GHL5 PF14872.6 RLN14639.1 - 0.014 13.4 0.0 0.016 13.3 0.0 1.0 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 AAA_6 PF12774.7 RLN14640.1 - 1.8e-142 474.1 0.0 3.1e-142 473.4 0.0 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN14640.1 - 2.1e-135 451.9 4.6 3.8e-135 451.0 4.6 1.4 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 RLN14640.1 - 5e-05 23.3 0.2 0.077 13.0 0.0 4.0 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 RLN14640.1 - 0.0055 17.3 0.7 0.19 12.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RLN14640.1 - 0.0083 15.7 0.2 1.4 8.4 0.1 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA PF00004.29 RLN14640.1 - 0.03 14.8 0.8 0.59 10.6 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rx_N PF18052.1 RLN14640.1 - 0.49 10.7 6.5 2.9 8.3 1.4 3.9 3 0 0 3 3 3 0 Rx N-terminal domain Flg_bb_rod PF00460.20 RLN14641.1 - 0.0045 16.9 2.4 0.0066 16.4 2.4 1.3 1 0 0 1 1 1 1 Flagella basal body rod protein TPR_10 PF13374.6 RLN14641.1 - 0.027 14.3 0.1 0.52 10.3 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat YL1 PF05764.13 RLN14642.1 - 0.0035 17.5 12.4 0.0035 17.5 12.4 2.6 2 1 0 2 2 2 1 YL1 nuclear protein UIM PF02809.20 RLN14642.1 - 0.0067 16.3 0.5 0.0067 16.3 0.5 2.8 2 0 0 2 2 2 1 Ubiquitin interaction motif RXT2_N PF08595.11 RLN14642.1 - 0.64 10.0 12.7 0.2 11.7 1.8 3.1 3 0 0 3 3 3 0 RXT2-like, N-terminal RPN2_C PF18004.1 RLN14642.1 - 1.1 9.1 6.9 7.6 6.4 2.7 2.8 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain FAM176 PF14851.6 RLN14642.1 - 4 7.1 13.8 5.9 6.6 3.9 3.6 3 0 0 3 3 3 0 FAM176 family BSP_II PF05432.11 RLN14642.1 - 6.2 6.4 14.0 1 9.0 5.9 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Pkinase PF00069.25 RLN14643.1 - 1.8e-55 188.2 0.0 2.5e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN14643.1 - 4.7e-28 98.2 0.0 1.5e-27 96.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN14643.1 - 5.9e-07 29.1 0.0 2.4e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN14643.1 - 0.0013 18.2 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN14643.1 - 0.15 12.0 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family EF-hand_6 PF13405.6 RLN14644.1 - 7.1e-11 41.1 5.4 9.7e-05 22.0 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 RLN14644.1 - 1.2e-10 40.2 9.2 4e-05 22.8 0.1 3.7 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 RLN14644.1 - 1.8e-07 31.5 0.7 0.052 14.0 0.0 3.7 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN14644.1 - 6.9e-06 25.3 9.3 0.012 15.1 0.0 3.9 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 RLN14644.1 - 0.095 12.6 3.7 0.39 10.6 0.2 3.0 3 0 0 3 3 3 0 EF-hand domain pair Peptidase_S10 PF00450.22 RLN14645.1 - 2.7e-79 267.5 4.0 3.6e-79 267.1 4.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Got1 PF04178.12 RLN14649.1 - 4.8e-31 107.5 10.5 6.9e-31 107.0 10.5 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family PspB PF06667.12 RLN14649.1 - 5.1 7.2 7.4 0.33 11.0 2.1 1.8 2 0 0 2 2 2 0 Phage shock protein B CBF PF03914.17 RLN14650.1 - 6.7e-55 185.7 0.0 6.7e-55 185.7 0.0 3.1 3 0 0 3 3 3 1 CBF/Mak21 family Pkr1 PF08636.10 RLN14650.1 - 2.1e-09 37.4 3.2 5.4e-09 36.1 3.2 1.6 1 0 0 1 1 1 1 ER protein Pkr1 DUF913 PF06025.12 RLN14650.1 - 0.0052 15.8 0.2 0.0052 15.8 0.2 3.1 3 1 0 3 3 3 1 Domain of Unknown Function (DUF913) Cnd1 PF12717.7 RLN14650.1 - 0.016 15.2 0.1 0.041 13.9 0.1 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 AAA PF00004.29 RLN14650.1 - 0.13 12.7 0.1 34 4.9 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN14650.1 - 0.18 12.0 0.3 0.65 10.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain zf-CCCH PF00642.24 RLN14655.1 - 1 9.4 4.4 2.2 8.3 4.4 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Stealth_CR2 PF11380.8 RLN14656.1 - 1.5e-34 118.4 0.0 7.9e-34 116.1 0.0 2.1 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 RLN14656.1 - 6e-13 48.5 2.0 1.7e-12 47.1 2.0 1.8 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 RLN14656.1 - 8.5e-10 38.2 0.0 2e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 RLN14656.1 - 2.4e-09 36.9 0.0 5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Pkinase PF00069.25 RLN14657.1 - 3.2e-50 170.9 0.0 4.1e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN14657.1 - 3.7e-40 137.8 0.0 5.2e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN14657.1 - 1.1e-05 24.4 0.0 1.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN14657.1 - 0.00061 19.2 0.0 0.00096 18.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RLN14657.1 - 0.0011 18.0 0.8 0.0029 16.6 0.8 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RLN14657.1 - 0.0026 17.7 0.0 0.0031 17.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN14657.1 - 0.017 14.5 0.1 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Closter_coat PF01785.17 RLN14657.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Closterovirus coat protein TSP_1 PF00090.19 RLN14658.1 - 1.5e-35 121.2 78.6 3.2e-05 24.0 0.2 12.7 12 1 0 12 12 12 10 Thrombospondin type 1 domain PTN_MK_C PF01091.18 RLN14658.1 - 1.2e-09 38.4 59.6 0.21 12.0 0.2 11.1 12 0 0 12 12 12 8 PTN/MK heparin-binding protein family, C-terminal domain Albumin_I PF08027.11 RLN14658.1 - 2.9 7.6 6.8 21 4.8 0.2 3.6 3 0 0 3 3 3 0 Albumin I chain b PALP PF00291.25 RLN14659.1 - 9.5e-65 218.9 2.9 1.6e-64 218.2 2.9 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CRAL_TRIO PF00650.20 RLN14659.1 - 1.5e-30 106.0 0.0 2.4e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain ACT PF01842.25 RLN14659.1 - 0.0019 17.9 0.0 0.0055 16.4 0.0 1.8 1 0 0 1 1 1 1 ACT domain PH PF00169.29 RLN14659.1 - 0.067 13.7 0.2 0.47 11.0 0.1 2.2 1 1 1 2 2 2 0 PH domain DUF4211 PF13926.6 RLN14660.1 - 6.1e-26 91.2 0.3 6.1e-26 91.2 0.3 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4211) zf-C3HC4_3 PF13920.6 RLN14660.1 - 3e-09 36.6 9.8 3e-09 36.6 9.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Dsh_C PF12316.8 RLN14660.1 - 3.1 8.2 7.6 1.4 9.3 1.2 2.4 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal TSP_1 PF00090.19 RLN14661.1 - 4.1e-08 33.3 12.9 0.01 16.1 0.5 3.6 3 0 0 3 3 3 3 Thrombospondin type 1 domain PB1 PF00564.24 RLN14662.1 - 1.6e-08 34.3 0.0 1.2e-07 31.6 0.0 2.4 3 0 0 3 3 3 1 PB1 domain CUE PF02845.16 RLN14662.1 - 1.8e-05 24.3 0.1 3.7e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 CUE domain B56 PF01603.20 RLN14662.1 - 0.014 14.4 0.8 0.021 13.8 0.8 1.2 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) WXG100 PF06013.12 RLN14662.1 - 0.06 13.6 4.5 0.17 12.2 3.3 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Toxin_trans PF07952.12 RLN14662.1 - 0.085 11.9 0.2 0.1 11.6 0.2 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain TIP120 PF08623.10 RLN14662.1 - 0.11 12.3 0.8 0.21 11.4 0.8 1.4 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) Dak2 PF02734.17 RLN14662.1 - 0.15 12.0 3.3 0.24 11.3 2.6 1.7 1 1 0 1 1 1 0 DAK2 domain hemP PF10636.9 RLN14662.1 - 0.15 11.9 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Hemin uptake protein hemP HisKA_3 PF07730.13 RLN14662.1 - 0.15 12.6 2.9 3.3 8.3 2.9 2.7 1 1 0 1 1 1 0 Histidine kinase Syntaxin_2 PF14523.6 RLN14662.1 - 0.45 10.9 3.8 1.1 9.7 3.5 1.7 1 1 0 1 1 1 0 Syntaxin-like protein DUF2524 PF10732.9 RLN14662.1 - 0.77 10.1 6.8 0.98 9.8 5.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2524) DUF883 PF05957.13 RLN14662.1 - 1.7 9.3 6.5 1.3 9.7 3.9 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) KxDL PF10241.9 RLN14662.1 - 1.9 8.8 8.2 1 9.7 3.8 2.7 3 1 0 3 3 3 0 Uncharacterized conserved protein DUF948 PF06103.11 RLN14662.1 - 1.9 8.8 4.7 27 5.1 4.7 2.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) YtxH PF12732.7 RLN14662.1 - 2 9.0 8.3 2.3e+02 2.4 8.3 2.9 1 1 0 1 1 1 0 YtxH-like protein PI3_PI4_kinase PF00454.27 RLN14663.1 - 4.7e-44 151.1 0.0 8.8e-43 146.9 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 RLN14663.1 - 9.2e-44 149.1 0.1 1.7e-43 148.2 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PH PF00169.29 RLN14663.1 - 3e-30 104.8 2.9 5.5e-15 55.8 0.4 3.1 3 0 0 3 3 3 2 PH domain PH_11 PF15413.6 RLN14663.1 - 6.8e-11 42.5 0.8 2e-05 24.9 0.0 2.9 2 0 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 RLN14663.1 - 9.5e-08 32.2 8.7 0.00062 20.0 1.7 4.3 4 1 0 4 4 4 2 Pleckstrin homology domain PI3K_rbd PF00794.18 RLN14663.1 - 1.8e-05 24.9 0.1 4.1e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 RLN14663.1 - 0.00011 22.1 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 RLN14663.1 - 0.0071 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) CRM1_C PF08767.11 RLN14663.1 - 0.066 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 CRM1 C terminal DUF2833 PF11090.8 RLN14663.1 - 0.15 12.5 0.2 0.92 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) PI3Ka PF00613.20 RLN14665.1 - 9.3e-43 145.8 0.2 2.2e-42 144.5 0.2 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PH PF00169.29 RLN14665.1 - 1.4e-30 105.9 1.3 2.8e-14 53.5 0.0 3.0 2 0 0 2 2 2 2 PH domain PI3_PI4_kinase PF00454.27 RLN14665.1 - 5.5e-20 72.2 0.0 1.1e-11 45.1 0.0 3.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PH_11 PF15413.6 RLN14665.1 - 2.7e-11 43.8 2.6 9.3e-05 22.8 0.0 2.8 2 0 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 RLN14665.1 - 6.6e-10 39.1 3.2 0.0006 20.0 1.3 3.6 2 1 0 2 2 2 2 Pleckstrin homology domain PI3K_rbd PF00794.18 RLN14665.1 - 1.3e-07 31.7 0.1 3.3e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 RLN14665.1 - 1.4e-05 25.1 0.0 2.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF2833 PF11090.8 RLN14665.1 - 0.011 16.1 0.0 0.068 13.6 0.0 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) CRM1_C PF08767.11 RLN14665.1 - 0.022 14.0 0.2 0.063 12.4 0.0 1.8 2 0 0 2 2 2 0 CRM1 C terminal HU-CCDC81_euk_2 PF18289.1 RLN14666.1 - 8.9e-13 48.2 0.1 1.9e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 RLN14666.1 - 0.0065 16.6 0.0 0.021 15.0 0.0 1.9 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 MBT PF02820.18 RLN14667.1 - 2.5e-07 31.0 0.2 3.1e-07 30.6 0.2 1.1 1 0 0 1 1 1 1 mbt repeat Tudor-knot PF11717.8 RLN14667.1 - 1.3e-05 24.9 2.1 2.7e-05 24.0 2.1 1.6 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain Tudor_4 PF18358.1 RLN14667.1 - 0.00049 19.6 0.2 0.00063 19.3 0.2 1.2 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain Suppressor_APC PF11414.8 RLN14667.1 - 0.0066 16.5 0.1 0.0084 16.2 0.1 1.1 1 0 0 1 1 1 1 Adenomatous polyposis coli tumour suppressor protein Ribosomal_L30_N PF08079.12 RLN14668.1 - 5.9e-24 84.1 9.9 5.9e-24 84.1 9.9 1.5 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 RLN14668.1 - 6.3e-22 77.2 2.0 1.2e-21 76.3 2.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e WD40 PF00400.32 RLN14670.1 - 0.077 13.9 0.1 0.83 10.6 0.0 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat Sec7 PF01369.20 RLN14671.1 - 2.7e-33 115.2 0.0 4e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain DASH_Ask1 PF08655.10 RLN14673.1 - 4.5e-08 32.9 0.1 9.1e-08 31.9 0.1 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 DUF755 PF05501.11 RLN14674.1 - 2.7 8.3 9.3 6.7 7.0 9.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF755) Apt1 PF10351.9 RLN14675.1 - 2.9e-27 95.7 0.0 6e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Golgi-body localisation protein domain Pkinase PF00069.25 RLN14676.1 - 2.4e-62 210.7 0.0 5.4e-62 209.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN14676.1 - 6.4e-24 84.6 0.0 1.1e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Epimerase PF01370.21 RLN14676.1 - 5.6e-10 39.1 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 RLN14676.1 - 2.1e-08 34.3 0.0 5.6e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 RLN14676.1 - 6.3e-07 28.8 0.0 1.1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 RLN14676.1 - 1.3e-05 24.8 0.0 2.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase WW PF00397.26 RLN14676.1 - 0.00035 20.6 0.1 0.001 19.1 0.1 1.8 1 0 0 1 1 1 1 WW domain 3Beta_HSD PF01073.19 RLN14676.1 - 0.0015 17.6 0.0 0.0027 16.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Haspin_kinase PF12330.8 RLN14676.1 - 0.045 12.7 0.1 0.075 12.0 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 RLN14676.1 - 0.054 12.8 0.6 0.12 11.7 0.6 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NmrA PF05368.13 RLN14676.1 - 0.1 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.15 RLN14676.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SnoaL_2 PF12680.7 RLN14676.1 - 0.14 12.8 2.5 0.19 12.4 0.3 2.5 2 0 0 2 2 1 0 SnoaL-like domain APH PF01636.23 RLN14676.1 - 0.99 9.3 3.9 0.33 10.9 0.1 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Stealth_CR2 PF11380.8 RLN14677.1 - 5.9e-36 122.9 0.0 1.3e-35 121.8 0.0 1.6 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 RLN14677.1 - 2.6e-12 46.4 3.7 5.2e-12 45.5 3.7 1.5 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 RLN14677.1 - 3.4e-05 23.5 0.0 7.7e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 RLN14677.1 - 0.0028 17.5 0.0 0.0063 16.4 0.0 1.5 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 DUF1548 PF07579.11 RLN14677.1 - 0.061 13.7 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) PetL PF05115.14 RLN14677.1 - 2 8.5 7.6 4.4 7.4 7.6 1.5 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) Glyco_hydro_1 PF00232.18 RLN14690.1 - 0.00067 18.2 0.0 0.00067 18.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 LPMO_10 PF03067.15 RLN14698.1 - 1.9e-09 38.5 0.1 1.9e-09 38.5 0.1 1.8 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 RLN14698.1 - 0.0014 18.6 0.3 0.058 13.3 0.1 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Alanine_zipper PF11839.8 RLN14698.1 - 0.31 11.4 1.5 0.59 10.5 1.5 1.4 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein SOG2 PF10428.9 RLN14698.1 - 0.33 10.1 5.9 0.44 9.7 5.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 RLN14698.1 - 0.95 8.1 3.4 1 8.0 3.4 1.1 1 0 0 1 1 1 0 Hamartin protein MSP1_C PF07462.11 RLN14698.1 - 1.9 7.1 12.2 3.2 6.4 12.2 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus MULE PF10551.9 RLN14706.1 - 2.2e-11 44.0 0.9 4.4e-11 43.0 0.9 1.5 1 0 0 1 1 1 1 MULE transposase domain DEAD PF00270.29 RLN14717.1 - 8.6e-08 32.1 0.0 3e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase Trehalose_PPase PF02358.16 RLN14719.1 - 1e-54 185.2 0.0 1.2e-54 184.9 0.0 1.0 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 RLN14719.1 - 0.00017 21.4 0.1 0.095 12.4 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 RLN14719.1 - 0.0017 17.9 0.0 0.007 15.9 0.0 1.8 1 1 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Wtap PF17098.5 RLN14719.1 - 0.17 11.8 0.0 3.7 7.5 0.0 2.1 2 0 0 2 2 2 0 WTAP/Mum2p family TauD PF02668.16 RLN14720.1 - 6e-26 91.8 1.3 1.5e-25 90.5 1.3 1.6 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family zf-HC5HC2H_2 PF13832.6 RLN14720.1 - 4.5e-09 36.5 5.6 4.5e-09 36.5 5.6 4.6 3 1 2 5 5 5 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RLN14720.1 - 1.3e-08 35.0 6.5 1.3e-08 35.0 6.5 4.1 3 1 0 4 4 4 1 PHD-like zinc-binding domain DUF971 PF06155.12 RLN14720.1 - 2.3e-08 34.5 0.1 8.9e-08 32.7 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF971) PHD_2 PF13831.6 RLN14720.1 - 6.7e-05 22.4 6.5 0.00028 20.4 0.3 3.4 2 0 0 2 2 2 1 PHD-finger Cofilin_ADF PF00241.20 RLN14721.1 - 2.3e-23 82.3 0.0 3e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein NDUFA12 PF05071.16 RLN14722.1 - 2.2e-15 57.3 1.6 2.2e-15 57.3 1.6 2.0 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 TPT PF03151.16 RLN14723.1 - 5.9e-26 91.5 13.9 7.7e-26 91.1 13.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 RLN14723.1 - 1.3e-05 25.4 26.2 0.00036 20.7 13.3 2.6 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 RLN14723.1 - 0.00022 20.5 13.0 0.00034 19.9 13.0 1.3 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 RLN14723.1 - 0.23 10.6 20.6 0.26 10.5 18.2 2.2 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport TRAP_alpha PF03896.16 RLN14725.1 - 0.2 10.8 2.1 0.23 10.6 2.1 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit WD40 PF00400.32 RLN14726.1 - 9.8e-15 54.7 16.1 1.6e-07 31.9 2.7 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN14726.1 - 1.5e-07 31.6 2.9 0.009 16.3 0.1 4.8 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PG_binding_4 PF12229.8 RLN14726.1 - 0.15 12.3 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative peptidoglycan binding domain PDZ_6 PF17820.1 RLN14727.1 - 1.6e-05 24.6 0.0 3.8e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RLN14727.1 - 0.00037 20.8 0.0 0.00075 19.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RLN14727.1 - 0.0056 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Octopine_DH PF02317.17 RLN14727.1 - 0.21 11.7 0.5 0.51 10.4 0.5 1.6 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain WD40 PF00400.32 RLN14728.1 - 4.7e-18 65.2 8.5 3.4e-06 27.7 0.0 5.9 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN14728.1 - 0.087 13.1 0.3 23 5.4 0.0 3.1 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase_Tyr PF07714.17 RLN14729.1 - 3.4e-28 98.6 0.0 4.3e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN14729.1 - 3.2e-18 66.1 0.0 4.3e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Mg_trans_NIPA PF05653.14 RLN14730.1 - 5.5e-33 114.3 16.5 7.5e-33 113.9 16.5 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA Fz PF01392.22 RLN14730.1 - 0.00021 21.9 3.7 0.00039 21.0 3.7 1.4 1 0 0 1 1 1 1 Fz domain EamA PF00892.20 RLN14730.1 - 0.0011 19.2 7.8 0.0011 19.2 7.8 3.3 2 1 1 3 3 3 1 EamA-like transporter family TMEM234 PF10639.9 RLN14730.1 - 0.077 13.0 7.4 0.086 12.9 0.9 2.4 2 0 0 2 2 2 0 Putative transmembrane family 234 BT1 PF03092.16 RLN14731.1 - 2e-11 42.8 0.3 2e-11 42.8 0.3 2.9 1 1 1 2 2 2 2 BT1 family PUCC PF03209.15 RLN14731.1 - 0.0021 17.2 11.6 0.011 14.8 8.8 2.5 2 1 0 2 2 2 1 PUCC protein EF-hand_7 PF13499.6 RLN14732.1 - 3.6e-16 59.4 0.4 0.0033 17.8 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 RLN14732.1 - 6.2e-08 31.7 0.0 3.2 7.5 0.0 6.2 6 0 0 6 6 6 2 EF hand EF-hand_8 PF13833.6 RLN14732.1 - 2.3e-07 30.6 0.2 0.027 14.3 0.0 5.4 5 2 1 6 6 6 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN14732.1 - 1.9e-05 24.2 0.0 5.5 7.2 0.0 5.0 5 0 0 5 5 5 2 EF-hand domain RIIa PF02197.17 RLN14732.1 - 0.051 13.2 0.1 15 5.3 0.0 2.6 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit EF-hand_4 PF12763.7 RLN14732.1 - 0.14 12.2 0.1 4.1 7.4 0.0 2.8 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand PIP5K PF01504.18 RLN14733.1 - 4.4e-35 121.2 0.0 7.9e-19 67.9 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase OmpA_like PF16961.5 RLN14733.1 - 0.018 14.7 0.1 0.047 13.4 0.0 1.7 2 0 0 2 2 2 0 Putative OmpA-OmpF-like porin family PH PF00169.29 RLN14741.1 - 1.4e-17 64.1 0.0 3.3e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 PH domain PTEN_C2 PF10409.9 RLN14741.1 - 2.1e-14 53.4 0.0 3.5e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein PH_11 PF15413.6 RLN14741.1 - 3.1e-06 27.6 0.0 6.7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DSPc PF00782.20 RLN14741.1 - 3.6e-06 26.8 0.0 7.8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 RLN14741.1 - 7.1e-05 22.9 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 RLN14741.1 - 0.00042 20.0 0.0 0.00071 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 RLN14741.1 - 0.01 15.9 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate PH_9 PF15410.6 RLN14741.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Y_phosphatase2 PF03162.13 RLN14741.1 - 0.2 11.3 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Aa_trans PF01490.18 RLN14742.1 - 7.5e-44 150.1 6.2 4.9e-23 81.5 1.9 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Pkinase PF00069.25 RLN14742.1 - 1.1e-20 74.1 0.0 3.1e-20 72.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN14742.1 - 2.4e-14 53.3 0.0 3.7e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN14742.1 - 0.021 14.2 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TMEM100 PF16311.5 RLN14742.1 - 0.036 13.6 0.2 0.085 12.5 0.2 1.6 1 0 0 1 1 1 0 Transmembrane protein 100 FYVE PF01363.21 RLN14745.1 - 0.16 12.1 18.6 0.37 11.0 18.6 1.6 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN14745.1 - 0.68 10.2 15.1 1.7 8.9 15.1 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger PALP PF00291.25 RLN14746.1 - 6.6e-46 157.1 0.1 2.1e-33 116.0 0.0 2.5 2 1 1 3 3 3 2 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 RLN14746.1 - 2.1e-14 53.7 0.1 8.5e-08 32.5 0.0 2.9 3 0 0 3 3 3 2 CBS domain Sugar-bind PF04198.13 RLN14746.1 - 0.15 11.2 0.1 4.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Putative sugar-binding domain DAGK_cat PF00781.24 RLN14746.1 - 0.19 11.3 0.4 0.99 9.0 0.0 2.3 3 0 0 3 3 3 0 Diacylglycerol kinase catalytic domain SHMT PF00464.19 RLN14747.1 - 2e-172 573.3 0.0 2.4e-172 573.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 RLN14747.1 - 3.2e-05 23.4 0.0 0.00011 21.5 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase PSS PF03034.15 RLN14748.1 - 4.6e-74 249.6 13.6 1.2e-38 133.4 4.1 2.3 1 1 1 2 2 2 2 Phosphatidyl serine synthase DUF3382 PF11862.8 RLN14748.1 - 0.18 12.1 5.1 0.41 10.9 0.1 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3382) Got1 PF04178.12 RLN14807.1 - 2.1e-21 76.4 10.4 2.4e-21 76.3 10.4 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family PGG PF13962.6 RLN14807.1 - 0.015 15.2 6.0 0.016 15.0 1.8 2.0 1 1 1 2 2 2 0 Domain of unknown function DUF2105 PF09878.9 RLN14807.1 - 0.051 13.3 4.8 0.063 13.0 4.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2105) FA_desaturase PF00487.24 RLN14807.1 - 0.38 10.6 10.2 0.44 10.3 10.2 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Hydrolase_4 PF12146.8 RLN14808.1 - 5.6e-54 182.9 0.2 6.9e-54 182.6 0.2 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN14808.1 - 1.3e-11 44.6 0.1 2.9e-11 43.5 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN14808.1 - 3.3e-09 37.7 0.8 3.3e-09 37.7 0.8 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 RLN14808.1 - 4.6e-09 36.1 0.0 0.003 17.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 RLN14808.1 - 0.00076 19.4 0.1 0.0017 18.3 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 RLN14808.1 - 0.0021 17.9 0.2 0.79 9.5 0.0 2.6 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 RLN14808.1 - 0.0054 16.3 0.0 0.0079 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Peptidase_S15 PF02129.18 RLN14808.1 - 0.014 15.0 0.0 0.075 12.6 0.0 1.9 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_8 PF06259.12 RLN14808.1 - 0.11 12.2 0.3 0.27 10.9 0.1 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase Ser_hydrolase PF06821.13 RLN14808.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Sec7 PF01369.20 RLN14809.1 - 4.1e-64 215.6 0.0 7.8e-64 214.7 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain DUF1981 PF09324.10 RLN14809.1 - 1.6e-28 98.3 0.0 6.8e-27 93.2 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) Mon2_C PF16206.5 RLN14809.1 - 3.2e-05 22.3 0.1 0.00033 19.0 0.0 2.1 2 0 0 2 2 2 1 C-terminal region of Mon2 protein IlvGEDA_leader PF08046.11 RLN14810.1 - 5.6 6.5 7.4 0.26 10.8 1.2 2.0 3 0 0 3 3 3 0 IlvGEDA operon leader peptide Abhydrolase_1 PF00561.20 RLN14812.1 - 5.8e-13 49.1 0.2 2.1e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 RLN14812.1 - 9.6e-06 25.7 0.0 0.00028 21.0 0.0 2.3 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.8 RLN14812.1 - 0.00038 19.8 0.0 0.13 11.5 0.0 2.5 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN14812.1 - 0.0021 18.7 3.4 0.0051 17.4 3.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family FYVE PF01363.21 RLN14814.1 - 4.1e-10 39.6 13.7 9.8e-10 38.4 13.7 1.7 1 0 0 1 1 1 1 FYVE zinc finger SlyX PF04102.12 RLN14814.1 - 6.6 7.4 13.8 15 6.3 10.5 3.4 2 0 0 2 2 2 0 SlyX XRCC4 PF06632.12 RLN14815.1 - 3.5 6.4 10.8 5.7 5.7 10.8 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 PDZ PF00595.24 RLN14816.1 - 7.4e-07 29.4 0.0 0.0022 18.3 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 RLN14816.1 - 1.2e-06 28.2 1.6 0.052 13.4 0.1 2.8 3 0 0 3 3 3 2 PDZ domain Rootletin PF15035.6 RLN14826.1 - 0.0039 17.2 7.6 0.0039 17.2 7.6 2.4 2 1 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion DUF4349 PF14257.6 RLN14826.1 - 0.13 11.7 14.0 0.022 14.2 9.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Las1 PF04031.13 RLN14826.1 - 0.18 11.9 2.7 0.19 11.9 0.9 1.9 2 0 0 2 2 2 0 Las1-like V_ATPase_I PF01496.19 RLN14826.1 - 1.2 6.9 8.7 2.1 6.2 8.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family mRNA_cap_enzyme PF01331.19 RLN14827.1 - 1.1e-20 74.4 0.0 1.4e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.21 RLN14827.1 - 0.0034 17.0 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain Robl_LC7 PF03259.17 RLN14830.1 - 1.5e-07 31.1 0.0 2.1e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain DUF4070 PF13282.6 RLN14830.1 - 0.077 13.1 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) NDUFB10 PF10249.9 RLN14831.1 - 0.021 15.3 0.5 0.021 15.3 0.5 2.8 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit 10 Tnp_22_trimer PF17489.2 RLN14831.1 - 0.07 13.1 0.2 0.07 13.1 0.2 3.7 5 0 0 5 5 5 0 L1 transposable element trimerization domain Antibiotic_NAT PF02522.14 RLN14831.1 - 0.076 12.8 0.7 0.17 11.7 0.1 1.9 2 0 0 2 2 2 0 Aminoglycoside 3-N-acetyltransferase CR6_interact PF10147.9 RLN14831.1 - 6.4 6.4 13.1 0.46 10.2 3.9 3.0 3 1 0 3 3 3 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Patched PF02460.18 RLN14834.1 - 4.7e-68 230.1 19.7 2.1e-45 155.1 0.7 3.3 2 1 1 3 3 3 2 Patched family Sterol-sensing PF12349.8 RLN14834.1 - 2.3e-34 118.5 7.3 2.3e-34 118.5 7.3 3.0 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation NPC1_N PF16414.5 RLN14834.1 - 3.4e-19 69.4 13.9 3.4e-19 69.4 13.9 1.7 2 0 0 2 2 2 1 Niemann-Pick C1 N terminus MMPL PF03176.15 RLN14834.1 - 0.48 9.3 11.1 0.79 8.6 7.0 2.6 2 0 0 2 2 2 0 MMPL family ACR_tran PF00873.19 RLN14834.1 - 1.7 6.2 12.8 0.075 10.7 7.0 1.5 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family PDZ_6 PF17820.1 RLN14835.1 - 7.8e-13 48.1 0.0 0.00073 19.3 0.0 4.6 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.24 RLN14835.1 - 3.6e-09 36.9 0.0 0.12 12.7 0.0 4.0 3 0 0 3 3 3 3 PDZ domain IMS PF00817.20 RLN14835.1 - 6e-08 32.8 0.1 7e-07 29.3 0.0 2.7 3 0 0 3 3 3 1 impB/mucB/samB family zf_UBZ PF18439.1 RLN14835.1 - 7.2e-08 31.9 0.7 1.8e-07 30.7 0.7 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 RLN14835.1 - 0.0099 16.6 1.4 0.036 14.8 0.1 2.8 3 0 0 3 3 3 1 impB/mucB/samB family C-terminal domain EF-hand_1 PF00036.32 RLN14836.1 - 4.7e-08 32.0 4.0 1.2e-06 27.6 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 RLN14836.1 - 6e-08 32.4 1.7 2.8e-06 27.1 0.3 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN14836.1 - 1.3e-05 24.7 0.3 0.0045 16.8 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 RLN14836.1 - 2e-05 23.9 0.2 0.0013 18.2 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 RLN14836.1 - 0.00022 21.6 0.8 0.0031 17.9 0.7 2.8 1 1 0 1 1 1 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RLN14836.1 - 0.9 9.9 3.1 0.94 9.8 0.1 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region GST_C_2 PF13410.6 RLN14837.1 - 1.7e-08 34.3 0.1 4.3e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RLN14837.1 - 4.9e-06 26.7 0.1 4.1e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RLN14837.1 - 6.2e-05 23.1 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RLN14837.1 - 0.00038 20.6 0.0 0.00073 19.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 RLN14837.1 - 0.0008 19.2 0.1 0.0016 18.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pkinase PF00069.25 RLN14838.1 - 2.1e-39 135.5 0.0 3.2e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN14838.1 - 6.7e-36 123.9 0.0 2.3e-35 122.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase DnaJ PF00226.31 RLN14870.1 - 6.6e-14 51.8 0.4 1.2e-13 50.9 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain DUF4523 PF15023.6 RLN14870.1 - 0.0086 15.9 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) Rad60-SLD PF11976.8 RLN14870.1 - 0.0088 15.9 0.0 0.094 12.6 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 RLN14870.1 - 0.0091 15.9 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.23 RLN14870.1 - 0.074 12.8 0.0 0.51 10.1 0.0 2.3 1 1 0 1 1 1 0 Ubiquitin family APG17 PF04108.12 RLN14871.1 - 0.028 13.5 0.1 0.04 13.0 0.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 DASH_Dad1 PF08649.10 RLN14872.1 - 0.0073 16.5 3.2 0.16 12.2 0.6 2.2 1 1 1 2 2 2 2 DASH complex subunit Dad1 Peptidase_S74 PF13884.6 RLN14875.1 - 1.9e-12 47.3 0.3 3e-12 46.7 0.3 1.3 1 0 0 1 1 1 1 Chaperone of endosialidase RHD3 PF05879.12 RLN14876.1 - 3e-06 25.7 0.0 4.4e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 RLN14876.1 - 1.2e-05 24.7 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 RLN14876.1 - 0.009 16.1 0.0 0.035 14.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 RLN14876.1 - 0.018 15.1 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Dynamin family FeoB_N PF02421.18 RLN14876.1 - 0.14 11.7 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B LigB PF02900.18 RLN14877.1 - 4.1e-18 65.4 0.0 8e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Mg_trans_NIPA PF05653.14 RLN14878.1 - 6.2e-11 41.9 6.0 6.2e-11 41.9 6.0 2.4 2 1 0 2 2 2 1 Magnesium transporter NIPA EamA PF00892.20 RLN14878.1 - 0.086 13.0 19.9 0.078 13.1 5.8 3.3 2 2 0 2 2 2 0 EamA-like transporter family KIAA1430 PF13879.6 RLN14879.1 - 0.019 15.7 0.3 0.019 15.7 0.3 3.0 2 1 1 3 3 3 0 KIAA1430 homologue DASH_Dad2 PF08654.10 RLN14879.1 - 0.065 13.7 2.9 0.72 10.3 0.0 3.6 4 0 0 4 4 4 0 DASH complex subunit Dad2 DCB PF16213.5 RLN14879.1 - 3.3 7.3 7.1 3.3 7.4 0.0 4.1 3 1 2 5 5 5 0 Dimerisation and cyclophilin-binding domain of Mon2 V-SNARE PF05008.15 RLN14880.1 - 1e-09 38.6 4.8 1.5e-06 28.4 0.7 2.3 2 0 0 2 2 2 2 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 RLN14880.1 - 2.5e-06 27.3 1.2 0.0012 18.7 0.0 3.0 2 1 1 3 3 3 2 Sec20 DUF3899 PF13038.6 RLN14880.1 - 0.037 14.5 0.2 2.5 8.6 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) TRAP-gamma PF07074.12 RLN14880.1 - 0.052 13.1 0.1 0.052 13.1 0.1 1.8 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF4337 PF14235.6 RLN14880.1 - 2.4 8.2 5.4 1.5 9.0 1.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) TRIQK PF15168.6 RLN14881.1 - 0.0099 15.8 0.7 0.0099 15.8 0.7 1.7 2 0 0 2 2 1 1 Triple QxxK/R motif-containing protein family DUF4448 PF14610.6 RLN14881.1 - 0.016 15.0 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Shisa PF13908.6 RLN14881.1 - 0.021 15.1 0.1 0.053 13.8 0.0 1.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator TrbC PF04956.13 RLN14881.1 - 0.068 13.4 0.6 0.38 11.0 0.1 2.1 2 0 0 2 2 2 0 TrbC/VIRB2 family Trp_oprn_chp PF09534.10 RLN14881.1 - 0.068 13.0 1.4 3.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TFIIF_alpha PF05793.12 RLN14881.1 - 0.1 11.1 12.9 0.13 10.8 12.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ABC2_membrane_2 PF12679.7 RLN14881.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Orf78 PF06024.12 RLN14881.1 - 0.16 12.3 0.4 0.32 11.3 0.1 1.7 2 0 0 2 2 1 0 Orf78 (ac78) AAA_11 PF13086.6 RLN14881.1 - 0.17 11.7 5.4 0.2 11.4 5.4 1.1 1 0 0 1 1 1 0 AAA domain DUF3464 PF11947.8 RLN14881.1 - 0.42 10.3 4.6 0.11 12.2 1.4 1.7 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 AP3D1 PF06375.11 RLN14881.1 - 0.45 10.7 15.6 0.59 10.4 15.5 1.3 1 1 0 1 1 1 0 AP-3 complex subunit delta-1 Tombus_movement PF05318.12 RLN14881.1 - 0.58 11.0 6.9 0.35 11.7 4.9 1.7 2 0 0 2 2 1 0 Tombusvirus movement protein RR_TM4-6 PF06459.12 RLN14881.1 - 1.6 8.5 11.0 2.2 8.0 11.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Gastrin PF00918.17 RLN14881.1 - 2.7 9.0 10.1 0.15 13.0 0.4 2.2 1 1 1 2 2 2 0 Gastrin/cholecystokinin family DUF913 PF06025.12 RLN14881.1 - 5.5 5.9 6.2 7.9 5.3 6.2 1.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) Ctr PF04145.15 RLN14881.1 - 6 7.5 4.8 27 5.4 4.8 2.0 1 1 0 1 1 1 0 Ctr copper transporter family Connexin PF00029.19 RLN14881.1 - 9.2 5.9 7.0 18 5.0 7.0 1.7 1 1 0 1 1 1 0 Connexin Peptidase_M22 PF00814.25 RLN14882.1 - 3.3e-36 125.4 0.0 3.4e-25 89.3 0.0 2.1 1 1 1 2 2 2 2 Glycoprotease family UPF0524 PF15823.5 RLN14883.1 - 0.0058 16.1 0.1 0.0086 15.5 0.1 1.2 1 0 0 1 1 1 1 UPF0524 of C3orf70 GTP_EFTU_D3 PF03143.17 RLN14883.1 - 0.14 12.5 0.0 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu C-terminal domain bZIP_2 PF07716.15 RLN14889.1 - 2.9e-05 24.0 15.8 0.0003 20.8 7.0 2.4 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 RLN14889.1 - 0.00032 20.7 6.7 0.00032 20.7 6.7 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 RLN14889.1 - 0.028 15.0 16.8 0.078 13.5 15.6 2.1 1 1 1 2 2 2 0 bZIP Maf transcription factor NuiA PF07924.11 RLN14889.1 - 0.068 13.6 1.6 0.14 12.5 1.6 1.5 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein Med21 PF11221.8 RLN14889.1 - 0.093 13.0 4.0 0.18 12.0 4.0 1.5 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Rab3-GTPase_cat PF13890.6 RLN14892.1 - 2.4e-53 180.1 0.4 4.9e-53 179.1 0.4 1.6 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit PAN_4 PF14295.6 RLN14893.1 - 2.5e-40 136.2 36.3 1.5e-11 44.0 3.4 4.4 4 0 0 4 4 4 4 PAN domain PAN_2 PF08276.11 RLN14893.1 - 0.0007 19.7 40.8 0.14 12.3 4.4 4.3 4 0 0 4 4 4 4 PAN-like domain TBCC_N PF16752.5 RLN14894.1 - 0.055 13.9 0.7 1.2 9.6 0.0 2.9 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain Tape_meas_lam_C PF09718.10 RLN14895.1 - 0.091 12.9 0.2 0.2 11.8 0.2 1.5 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Pectate_lyase PF03211.13 RLN14896.1 - 1.5e-158 524.2 21.2 1.2e-80 269.9 7.4 2.4 2 0 0 2 2 2 2 Pectate lyase Bacteriocin_II PF01721.18 RLN14896.1 - 0.024 14.7 7.2 1.5 9.0 0.7 2.9 2 0 0 2 2 2 0 Class II bacteriocin FAM196 PF15265.6 RLN14896.1 - 0.19 11.2 8.0 0.26 10.7 8.0 1.1 1 0 0 1 1 1 0 FAM196 family gp37_C PF12604.8 RLN14896.1 - 1.6 8.4 8.5 1.6 8.4 0.1 3.0 3 1 0 3 3 3 0 Tail fibre protein gp37 C terminal Hamartin PF04388.12 RLN14896.1 - 2.2 6.8 7.8 2.9 6.5 7.8 1.1 1 0 0 1 1 1 0 Hamartin protein Nop14 PF04147.12 RLN14896.1 - 2.7 6.1 12.6 3.6 5.7 12.6 1.0 1 0 0 1 1 1 0 Nop14-like family Mitofilin PF09731.9 RLN14896.1 - 2.8 6.7 9.4 3.8 6.3 9.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Pro_isomerase PF00160.21 RLN14898.1 - 1.1e-21 77.8 0.0 6.1e-19 68.8 0.0 3.0 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Myosin_head PF00063.21 RLN14899.1 - 1.8e-204 680.9 0.0 2.7e-204 680.2 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) FYVE PF01363.21 RLN14899.1 - 6.6e-12 45.4 11.3 1.7e-11 44.1 11.3 1.7 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 RLN14899.1 - 3.5 7.9 11.8 8.2 6.7 11.8 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger Annexin PF00191.20 RLN14900.1 - 3.5e-60 200.0 1.3 4e-16 58.8 0.0 4.1 4 0 0 4 4 4 4 Annexin tRNA_anti_2 PF13742.6 RLN14901.1 - 0.00012 22.2 0.0 0.00018 21.6 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-codon PF01336.25 RLN14901.1 - 0.00049 20.0 0.0 0.00074 19.5 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RNase_HII PF01351.18 RLN14902.1 - 1.3e-38 132.8 0.0 1.6e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII APG17 PF04108.12 RLN14902.1 - 0.097 11.8 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 TPR_2 PF07719.17 RLN14916.1 - 5e-21 73.1 1.6 0.00088 19.2 0.1 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 RLN14916.1 - 7.8e-18 63.5 0.1 0.0014 18.3 0.1 6.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 RLN14916.1 - 5.4e-13 48.0 2.1 0.0024 17.9 0.1 6.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 RLN14916.1 - 2.8e-11 43.8 0.2 0.073 13.6 0.0 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 RLN14916.1 - 3.4e-11 42.7 1.9 7.9e-05 22.8 0.0 5.2 6 0 0 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN14916.1 - 6.9e-11 42.2 4.9 9.7e-07 28.9 0.4 4.7 3 2 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 RLN14916.1 - 2.3e-09 37.4 3.0 0.0047 17.2 0.0 5.4 4 3 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 RLN14916.1 - 4.7e-08 33.2 4.6 1.3 9.8 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN14916.1 - 9.6e-08 32.2 1.2 7.4 7.7 0.0 5.9 4 1 3 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN14916.1 - 4.2e-07 29.5 0.2 0.00033 20.3 0.0 3.7 3 1 1 4 4 4 1 TPR repeat TPR_16 PF13432.6 RLN14916.1 - 4.3e-07 30.5 0.0 0.053 14.2 0.0 3.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN14916.1 - 4.6e-05 23.2 0.3 5.1 7.4 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN14916.1 - 0.011 15.6 0.2 0.97 9.4 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.16 RLN14917.1 - 5.1e-06 25.7 14.2 5.1e-06 25.7 14.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5464 PF17552.2 RLN14917.1 - 2.2 8.6 13.8 0.13 12.5 7.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5464) ABC2_membrane PF01061.24 RLN14918.1 - 5.6e-66 222.0 71.5 1e-39 136.2 25.3 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN14918.1 - 1.1e-32 113.4 0.0 8.8e-17 61.9 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 RLN14918.1 - 2.1e-09 37.2 8.0 2.3e-08 33.8 0.1 3.6 3 0 0 3 3 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 RLN14918.1 - 2.8e-09 36.6 51.4 0.00024 20.3 20.3 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 RLN14918.1 - 9.4e-07 28.9 0.0 0.081 12.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN14918.1 - 7.6e-06 26.4 0.2 0.18 12.1 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 RLN14918.1 - 1.4e-05 24.7 6.0 0.024 14.4 1.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN14918.1 - 1.9e-05 24.6 1.7 0.0079 16.1 0.3 2.3 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 RLN14918.1 - 4.3e-05 22.9 0.7 0.0065 15.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 RLN14918.1 - 0.00023 21.4 0.5 0.42 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 RLN14918.1 - 0.00086 18.9 0.4 0.38 10.3 0.1 2.7 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 RLN14918.1 - 0.0019 18.2 0.0 7 6.5 0.0 3.2 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA PF00004.29 RLN14918.1 - 0.0026 18.2 0.1 4.2 7.8 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 RLN14918.1 - 0.003 17.3 0.3 1.3 8.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 RLN14918.1 - 0.0069 15.8 3.0 10 5.5 0.1 3.8 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 RLN14918.1 - 0.024 15.2 0.0 12 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain PDR_assoc PF08370.11 RLN14918.1 - 0.028 14.2 0.3 0.028 14.2 0.3 3.6 4 0 0 4 4 2 0 Plant PDR ABC transporter associated AAA_23 PF13476.6 RLN14918.1 - 0.029 14.9 4.8 0.32 11.5 0.6 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 RLN14918.1 - 0.038 14.1 1.0 6.8 6.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 RLN14918.1 - 0.11 12.7 0.1 6.6 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RLN14918.1 - 0.14 12.1 3.7 9 6.2 0.6 2.5 2 0 0 2 2 2 0 NACHT domain Roc PF08477.13 RLN14918.1 - 0.24 11.6 1.2 13 6.0 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ploopntkinase3 PF18751.1 RLN14918.1 - 0.28 11.1 0.7 2.7 7.9 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 RLN14918.1 - 0.34 10.6 1.5 16 5.1 0.2 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 RLN14918.1 - 0.36 10.4 3.0 3 7.4 0.5 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 RLN14918.1 - 0.71 9.6 3.0 4.8 6.9 0.2 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 RLN14918.1 - 3.7 7.6 5.0 28 4.7 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Oxidored_molyb PF00174.19 RLN14921.1 - 2.7e-58 196.4 0.0 4.5e-58 195.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 RLN14921.1 - 9.3e-44 148.8 0.8 2.1e-43 147.7 0.8 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 RLN14921.1 - 8e-15 54.7 0.1 2.7e-14 53.1 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF4658 PF15555.6 RLN14921.1 - 0.16 12.1 0.0 13 5.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) BNR PF02012.20 RLN14921.1 - 0.32 11.2 1.7 0.8 10.0 0.2 2.6 2 0 0 2 2 2 0 BNR/Asp-box repeat MCM PF00493.23 RLN14922.1 - 4.2e-83 277.9 0.0 8.4e-83 276.9 0.0 1.5 1 1 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RLN14922.1 - 1.1e-31 109.3 0.1 1.9e-31 108.6 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RLN14922.1 - 1.2e-22 80.1 0.4 2.4e-22 79.2 0.4 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 RLN14922.1 - 1.7e-11 44.7 0.0 3.8e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 RLN14922.1 - 5.5e-08 32.4 0.0 1.2e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RLN14922.1 - 0.0018 18.1 0.0 0.0042 16.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RLN14922.1 - 0.011 15.4 0.0 0.035 13.8 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF3583 PF12126.8 RLN14922.1 - 0.073 12.5 0.9 0.13 11.7 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) AAA_5 PF07728.14 RLN14922.1 - 0.097 12.7 0.0 0.32 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TauE PF01925.19 RLN14923.1 - 6.7e-36 124.1 19.3 1.7e-19 70.4 3.1 2.0 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE SBF PF01758.16 RLN14923.1 - 2.3 7.8 6.5 2.8 7.6 0.2 2.3 2 0 0 2 2 2 0 Sodium Bile acid symporter family DUF4833 PF16117.5 RLN14924.1 - 4.7e-40 136.8 0.0 8.6e-40 136.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4833) Hep_59 PF07052.11 RLN14924.1 - 1.6e-15 57.7 0.5 1.6e-15 57.7 0.5 3.4 4 0 0 4 4 4 1 Hepatocellular carcinoma-associated antigen 59 HAUS2 PF15003.6 RLN14924.1 - 0.043 13.5 1.5 0.08 12.7 1.5 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 Baculo_PEP_C PF04513.12 RLN14924.1 - 0.51 10.4 2.1 0.98 9.5 2.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LCD1 PF09798.9 RLN14924.1 - 4 5.8 9.8 6.3 5.2 9.8 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein PH PF00169.29 RLN14925.1 - 6.6e-14 52.3 0.0 1.2e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN14925.1 - 0.0043 17.4 0.0 0.0097 16.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Lipoprotein_20 PF13942.6 RLN14926.1 - 0.6 10.0 3.8 1 9.2 0.7 2.2 1 1 1 2 2 2 0 YfhG lipoprotein LKAAEAR PF15478.6 RLN14927.1 - 0.018 15.3 7.3 0.031 14.5 7.3 1.3 1 0 0 1 1 1 0 Family of unknown function with LKAAEAR motif OmpH PF03938.14 RLN14927.1 - 1.1 9.6 6.5 2 8.7 6.5 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) zf-HC5HC2H PF13771.6 RLN14928.1 - 0.0012 19.1 1.0 0.0033 17.6 1.0 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD PF00628.29 RLN14928.1 - 0.0048 16.8 7.9 0.0048 16.8 7.9 2.3 2 1 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 RLN14928.1 - 0.005 16.7 6.0 0.005 16.7 6.0 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-HC5HC2H_2 PF13832.6 RLN14928.1 - 0.039 14.1 1.7 0.09 13.0 1.7 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain Activator_LAG-3 PF11498.8 RLN14928.1 - 0.16 10.9 3.7 0.4 9.6 3.7 1.6 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PHD_4 PF16866.5 RLN14928.1 - 0.28 11.3 7.5 1.1 9.4 7.5 2.1 1 1 0 1 1 1 0 PHD-finger C1_2 PF03107.16 RLN14928.1 - 1.3 9.4 10.2 0.3 11.4 1.4 2.4 2 0 0 2 2 2 0 C1 domain DUF1840 PF08895.11 RLN14928.1 - 4.8 7.6 9.1 10 6.5 1.5 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF1840) Zf_RING PF16744.5 RLN14928.1 - 6.1 7.0 12.8 0.069 13.3 4.2 2.2 2 0 0 2 2 2 0 KIAA1045 RING finger Ribosomal_L18_c PF14204.6 RLN14928.1 - 7.7 7.5 7.0 20 6.2 0.9 2.7 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region MIP PF00230.20 RLN14929.1 - 3.6e-54 183.9 8.6 4.9e-54 183.4 8.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein Phage_holin_8 PF16931.5 RLN14929.1 - 0.029 14.4 0.1 0.091 12.7 0.1 1.9 1 0 0 1 1 1 0 Putative phage holin Polysacc_synt_C PF14667.6 RLN14929.1 - 0.033 14.2 7.5 6.9 6.7 0.0 3.3 3 0 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain CLZ PF16526.5 RLN14930.1 - 0.35 11.3 2.8 0.43 11.0 0.2 2.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tau95 PF09734.9 RLN14931.1 - 0.04 14.7 1.3 0.1 13.4 1.3 1.6 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain TSC22 PF01166.18 RLN14931.1 - 0.18 12.1 3.1 0.93 9.9 2.9 2.1 1 1 1 2 2 2 0 TSC-22/dip/bun family EMP24_GP25L PF01105.24 RLN14931.1 - 0.59 10.0 3.5 0.42 10.5 0.7 2.0 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Leader_Trp PF08255.11 RLN14931.1 - 0.76 9.9 5.1 6.2 7.1 0.3 2.7 2 0 0 2 2 2 0 Trp-operon Leader Peptide DUF4577 PF15145.6 RLN14933.1 - 0.22 11.6 0.1 0.43 10.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) DUF2570 PF10828.8 RLN14933.1 - 2 8.3 4.5 3.9 7.3 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) KH_1 PF00013.29 RLN14936.1 - 3.7e-40 135.6 0.0 1.2e-11 44.3 0.0 4.4 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 RLN14936.1 - 0.00041 20.2 0.0 0.064 13.1 0.0 2.6 2 0 0 2 2 2 2 KH domain XhlA PF10779.9 RLN14937.1 - 6.7 7.0 14.2 0.66 10.2 2.1 3.7 2 1 1 3 3 3 0 Haemolysin XhlA CHAT PF12770.7 RLN14938.1 - 3e-10 40.0 0.9 1.5e-09 37.7 0.9 2.0 1 1 0 1 1 1 1 CHAT domain AAA_16 PF13191.6 RLN14938.1 - 5.8e-07 30.0 0.3 1.7e-06 28.5 0.3 1.8 1 0 0 1 1 1 1 AAA ATPase domain SH2 PF00017.24 RLN14938.1 - 5.7e-05 23.1 0.0 0.00016 21.7 0.0 1.7 1 0 0 1 1 1 1 SH2 domain NACHT PF05729.12 RLN14938.1 - 0.0082 16.1 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain PhoH PF02562.16 RLN14938.1 - 0.0098 15.4 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 RLN14938.1 - 0.078 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 RLN14938.1 - 0.12 12.4 0.0 0.38 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 RLN14938.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea FGE-sulfatase PF03781.16 RLN14939.1 - 5.4e-24 85.2 2.9 1.5e-23 83.8 2.9 1.7 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 RWP-RK PF02042.15 RLN14940.1 - 8.9e-20 70.4 0.2 1.6e-19 69.6 0.2 1.4 1 0 0 1 1 1 1 RWP-RK domain Myb_DNA-binding PF00249.31 RLN14940.1 - 1.1e-11 44.7 0.2 2.3e-11 43.7 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN14940.1 - 0.0076 16.5 1.0 0.011 15.9 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN14940.1 - 0.01 15.7 0.2 0.033 14.1 0.0 1.9 2 0 0 2 2 2 0 Myb DNA-binding like DUF3774 PF12609.8 RLN14940.1 - 3.4 8.7 5.8 7.6 7.6 1.4 2.7 2 0 0 2 2 2 0 Wound-induced protein CAF1A PF12253.8 RLN14941.1 - 1.1e-22 80.0 2.8 1.1e-22 80.0 2.8 4.0 4 1 1 5 5 5 1 Chromatin assembly factor 1 subunit A COX5B PF01215.19 RLN14941.1 - 8.9e-11 41.6 0.0 2.2e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Mersacidin PF16934.5 RLN14941.1 - 0.3 10.9 1.9 1.9 8.3 0.4 2.9 2 0 0 2 2 2 0 Two-component Enterococcus faecalis cytolysin (EFC) DUF3537 PF12056.8 RLN14941.1 - 1.5 7.6 2.5 3.1 6.5 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) RRM_5 PF13893.6 RLN14942.1 - 3.2e-21 75.2 0.2 5.8e-10 38.8 0.0 3.7 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 RLN14942.1 - 1e-15 57.3 0.1 1.2e-06 28.2 0.0 4.4 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 RLN14942.1 - 4.9e-13 49.1 0.0 4.4e-12 46.1 0.1 2.2 2 0 0 2 2 2 1 RRM-like domain SelB-wing_1 PF09105.10 RLN14942.1 - 0.073 13.1 0.1 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Asp PF00026.23 RLN14943.1 - 1.5e-27 96.9 14.7 8.6e-27 94.4 14.7 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RLN14943.1 - 0.0003 21.1 11.2 0.005 17.1 0.7 3.2 2 2 2 4 4 4 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 RLN14943.1 - 0.0092 16.6 0.6 0.13 12.9 0.0 2.8 3 0 0 3 3 3 1 Aspartyl protease Cadherin_C_2 PF16492.5 RLN14943.1 - 0.011 16.5 0.0 0.035 14.9 0.0 1.9 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal CD34_antigen PF06365.12 RLN14943.1 - 0.025 14.2 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family TAXi_C PF14541.6 RLN14943.1 - 0.038 13.8 0.0 0.13 12.1 0.0 1.8 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 RLN14943.1 - 0.044 14.4 0.1 0.31 11.6 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease NUDIX PF00293.28 RLN14944.1 - 2.4e-14 53.5 0.0 3.1e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Sec6 PF06046.13 RLN14958.1 - 1.3e-23 83.2 6.7 2.3e-23 82.4 6.7 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 Aida_C2 PF14186.6 RLN14959.1 - 6.4e-39 132.9 1.6 3.2e-30 104.7 0.8 2.1 1 1 1 2 2 2 2 Cytoskeletal adhesion DUF748 PF05359.11 RLN14959.1 - 0.069 13.3 0.0 0.097 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF748) PX PF00787.24 RLN14960.1 - 1.7e-09 37.7 0.4 5.1e-09 36.1 0.4 1.8 1 0 0 1 1 1 1 PX domain IF-2B PF01008.17 RLN14961.1 - 2.6e-48 164.7 0.4 4.2e-48 164.0 0.4 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family YTH PF04146.15 RLN14962.1 - 2.4e-22 79.7 0.0 4e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain Dev_Cell_Death PF10539.9 RLN14962.1 - 1.6e-18 66.8 0.0 2.5e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Development and cell death domain zf-CCCH PF00642.24 RLN14962.1 - 1.6e-15 56.6 22.7 6.4e-09 35.5 1.6 3.9 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RLN14962.1 - 7.1e-13 48.1 39.0 1.5e-06 28.0 4.2 5.3 5 0 0 5 5 5 3 Zinc finger domain zf-CCCH_2 PF14608.6 RLN14962.1 - 3.5e-09 36.8 29.5 0.00059 20.2 0.4 4.8 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 RLN14962.1 - 6.2e-08 32.3 31.7 0.00015 21.5 0.8 4.6 3 1 1 4 4 4 3 CCCH-type zinc finger Torus PF16131.5 RLN14962.1 - 1.4e-06 28.9 18.1 0.005 17.5 1.1 3.4 2 1 1 3 3 3 2 Torus domain KH_1 PF00013.29 RLN14962.1 - 0.0011 18.7 0.1 0.0024 17.7 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCCH_3 PF15663.5 RLN14962.1 - 0.015 15.5 14.9 0.019 15.2 2.5 3.3 1 1 1 3 3 3 0 Zinc-finger containing family SARAF PF06682.12 RLN14962.1 - 0.11 12.2 0.1 0.11 12.2 0.1 1.7 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis PRP4 PF08799.11 RLN14963.1 - 4.3e-11 42.1 5.2 8.9e-11 41.1 5.2 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Prp18 PF02840.15 RLN14963.1 - 2.6e-10 40.5 0.1 2.6e-10 40.5 0.1 2.0 2 0 0 2 2 2 1 Prp18 domain Pex14_N PF04695.13 RLN14963.1 - 0.59 10.8 7.0 0.1 13.3 3.3 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 RLN14963.1 - 3.3 6.4 6.3 3.6 6.3 6.3 1.2 1 0 0 1 1 1 0 Presenilin Pkinase_Tyr PF07714.17 RLN14976.1 - 6.7e-56 189.4 0.0 1.5e-43 149.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN14976.1 - 1.4e-48 165.5 0.0 5.6e-37 127.5 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Arm PF00514.23 RLN14976.1 - 9.2e-23 79.5 12.4 0.061 13.4 0.0 12.4 13 1 1 14 14 14 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN14976.1 - 1.5e-05 25.3 23.5 0.015 15.7 0.3 6.1 4 1 1 5 5 5 3 HEAT repeats HEAT_EZ PF13513.6 RLN14976.1 - 0.0019 18.6 23.3 7.7 7.1 0.1 8.1 6 2 3 9 9 9 2 HEAT-like repeat Kinase-like PF14531.6 RLN14976.1 - 0.0097 15.2 0.0 0.12 11.6 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Glyco_hydro_17 PF00332.18 RLN14977.1 - 0.00016 21.4 0.1 0.00031 20.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 DUF3410 PF11890.8 RLN14977.1 - 0.07 12.9 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) Thi4 PF01946.17 RLN14991.1 - 8.4e-104 345.9 1.6 1.2e-103 345.5 1.6 1.1 1 0 0 1 1 1 1 Thi4 family DUF1126 PF06565.12 RLN14991.1 - 2e-44 149.7 0.8 6.3e-24 83.8 0.1 2.3 2 0 0 2 2 2 2 DUF1126 PH-like domain FAD_binding_2 PF00890.24 RLN14991.1 - 2.3e-07 30.2 4.8 2.9e-05 23.3 2.2 2.1 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.24 RLN14991.1 - 1.8e-06 27.8 3.7 2.1e-05 24.3 1.3 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 RLN14991.1 - 2.9e-06 26.9 0.2 4.7e-06 26.2 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RLN14991.1 - 8.4e-06 25.9 0.2 1.9e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 RLN14991.1 - 0.00024 20.5 0.1 0.00037 19.8 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 RLN14991.1 - 0.0015 17.7 2.6 0.13 11.3 0.8 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A GMC_oxred_N PF00732.19 RLN14991.1 - 0.0016 17.9 0.2 0.12 11.7 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase HI0933_like PF03486.14 RLN14991.1 - 0.0051 15.6 2.0 0.0064 15.2 0.6 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 RLN14991.1 - 0.0056 16.0 0.2 0.035 13.4 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 RLN14991.1 - 0.018 14.1 0.5 0.028 13.5 0.5 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 RLN14991.1 - 0.063 13.3 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 RLN14991.1 - 0.079 11.8 0.5 0.11 11.3 0.5 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 RLN14991.1 - 0.86 10.2 2.5 18 5.9 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SLAIN PF15301.6 RLN15030.1 - 3.3 6.8 5.4 4.3 6.5 5.4 1.1 1 0 0 1 1 1 0 SLAIN motif-containing family Voltage_CLC PF00654.20 RLN15031.1 - 4.4e-66 223.5 21.9 4.4e-66 223.5 21.9 1.6 1 1 1 2 2 2 1 Voltage gated chloride channel Atthog PF18800.1 RLN15031.1 - 0.027 14.3 0.1 0.069 13.0 0.1 1.6 1 0 0 1 1 1 0 Attenuator of Hedgehog CBS PF00571.28 RLN15031.1 - 0.11 12.9 0.9 6.4 7.3 0.2 2.5 2 0 0 2 2 2 0 CBS domain Glyco_transf_28 PF03033.20 RLN15032.1 - 3.3e-20 72.5 0.2 2.3e-19 69.8 0.2 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 RLN15032.1 - 0.00014 20.9 0.2 0.00028 19.8 0.2 1.5 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase DUF3482 PF11981.8 RLN15032.1 - 0.8 9.0 4.6 1.1 8.6 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Pkinase PF00069.25 RLN15033.1 - 1.2e-50 172.3 0.0 1.5e-49 168.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN15033.1 - 5.8e-25 88.0 0.0 5e-23 81.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN15033.1 - 1.5e-05 24.5 0.0 0.0029 17.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.11 RLN15033.1 - 0.00075 18.6 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 RLN15033.1 - 0.00096 18.0 0.0 0.001 18.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 RLN15033.1 - 0.00099 18.1 0.0 0.013 14.5 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_Tyr PF07714.17 RLN15059.1 - 4.2e-21 75.4 0.0 3.2e-20 72.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_1 PF00515.28 RLN15059.1 - 2.5e-19 68.2 23.9 0.00012 21.7 0.5 9.2 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 RLN15059.1 - 1.2e-17 62.5 31.2 0.001 19.0 0.5 9.5 10 0 0 10 10 9 5 Tetratricopeptide repeat Pkinase PF00069.25 RLN15059.1 - 2.6e-17 63.1 0.0 2.2e-16 60.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain TPR_11 PF13414.6 RLN15059.1 - 3.1e-13 49.2 20.1 1.4e-06 27.9 0.4 6.8 5 2 2 7 7 7 3 TPR repeat TPR_8 PF13181.6 RLN15059.1 - 1e-12 47.2 15.9 0.21 11.9 0.4 7.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 RLN15059.1 - 1.4e-09 38.0 22.3 0.22 12.4 1.2 8.7 6 2 4 10 10 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 RLN15059.1 - 2.3e-09 37.6 18.6 0.021 15.3 0.3 7.2 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 RLN15059.1 - 4.8e-05 23.4 10.9 0.14 12.6 0.1 5.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN15059.1 - 0.00018 21.6 15.1 0.12 12.5 2.4 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.6 RLN15059.1 - 0.0033 17.7 12.2 0.091 13.1 0.2 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat APH PF01636.23 RLN15059.1 - 0.0096 15.9 0.3 0.0096 15.9 0.3 3.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family TPR_12 PF13424.6 RLN15059.1 - 0.019 15.2 26.0 0.75 10.1 0.1 7.3 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 RLN15059.1 - 0.021 14.9 12.1 1.2 9.3 0.1 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 RLN15059.1 - 0.097 12.8 4.5 11 6.2 0.3 4.1 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 RLN15059.1 - 0.25 12.1 6.4 1.1 10.1 2.0 4.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN15059.1 - 1.3 9.8 34.1 0.33 11.6 0.3 7.4 6 1 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN15059.1 - 2.4 9.0 16.3 5.3 7.9 1.3 5.5 5 0 0 5 5 4 0 Tetratricopeptide repeat ABC2_membrane PF01061.24 RLN15062.1 - 2.6e-70 236.1 75.3 1.2e-40 139.1 27.1 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN15062.1 - 4.7e-37 127.6 0.1 4.4e-18 66.1 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 RLN15062.1 - 9.2e-10 38.3 0.1 5e-07 29.5 0.0 3.2 2 0 0 2 2 2 1 CDR ABC transporter AAA_21 PF13304.6 RLN15062.1 - 1.2e-07 31.8 0.1 0.02 14.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN15062.1 - 1.9e-07 31.6 0.1 0.018 15.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 RLN15062.1 - 9.6e-07 28.9 2.2 0.01 15.7 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 RLN15062.1 - 2.4e-05 24.0 6.7 0.02 14.6 1.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN15062.1 - 2.7e-05 24.4 0.0 0.092 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 RLN15062.1 - 3.5e-05 23.3 0.2 0.12 11.8 0.0 3.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain PDR_assoc PF08370.11 RLN15062.1 - 8.5e-05 22.2 11.7 0.001 18.7 0.4 3.5 3 0 0 3 3 2 2 Plant PDR ABC transporter associated Zeta_toxin PF06414.12 RLN15062.1 - 9e-05 21.8 0.7 0.012 14.9 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 RLN15062.1 - 0.00094 18.8 2.2 0.52 9.8 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 RLN15062.1 - 0.0024 18.4 0.0 1.9 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RLN15062.1 - 0.0028 17.4 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 RLN15062.1 - 0.0038 17.7 0.1 7.2 7.1 0.1 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 RLN15062.1 - 0.0052 16.8 1.0 1.2 9.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_5 PF07728.14 RLN15062.1 - 0.02 14.9 0.1 1.4 8.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 RLN15062.1 - 0.024 15.1 4.4 0.52 10.8 0.6 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RLN15062.1 - 0.046 13.6 2.5 7.4 6.5 0.4 2.5 2 0 0 2 2 2 0 NACHT domain Ploopntkinase3 PF18751.1 RLN15062.1 - 0.047 13.6 0.2 0.7 9.8 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 RLN15062.1 - 0.058 13.1 0.6 14 5.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RLN15062.1 - 0.069 13.4 1.2 16 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RLN15062.1 - 0.082 13.3 0.3 12 6.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase cobW PF02492.19 RLN15062.1 - 0.092 12.3 2.2 1.9 8.1 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 RLN15062.1 - 0.094 12.9 0.3 11 6.3 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 RLN15062.1 - 0.096 12.8 0.1 12 6.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 RLN15062.1 - 0.1 12.7 3.8 2.1 8.4 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Rad17 PF03215.15 RLN15062.1 - 0.14 12.1 0.0 7.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain DUF815 PF05673.13 RLN15062.1 - 0.23 10.6 0.9 0.58 9.3 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF815) ABC2_membrane_3 PF12698.7 RLN15062.1 - 0.43 9.6 61.8 0.16 11.1 29.3 3.7 2 2 0 2 2 2 0 ABC-2 family transporter protein PduV-EutP PF10662.9 RLN15062.1 - 0.49 10.1 1.9 5.4 6.7 0.4 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_ATPase PF09818.9 RLN15062.1 - 0.55 9.0 2.3 2 7.1 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Mg_chelatase PF01078.21 RLN15062.1 - 0.76 9.1 2.7 21 4.4 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI ABC2_membrane PF01061.24 RLN15063.1 - 1.5e-31 109.4 21.7 2.7e-31 108.6 21.7 1.4 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN15063.1 - 7.6e-07 28.9 0.1 2.9e-06 27.1 0.1 2.0 1 0 0 1 1 1 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 RLN15063.1 - 0.00018 20.8 19.1 0.00025 20.3 19.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein PDR_assoc PF08370.11 RLN15063.1 - 8.3 6.2 13.3 0.41 10.4 0.1 3.9 4 0 0 4 4 4 0 Plant PDR ABC transporter associated p450 PF00067.22 RLN15064.1 - 2.1e-43 148.7 0.1 2.5e-43 148.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC2_membrane PF01061.24 RLN15065.1 - 2.1e-66 223.4 63.8 7.1e-38 130.1 25.3 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN15065.1 - 5.9e-34 117.5 0.0 1.5e-15 57.9 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 RLN15065.1 - 2.5e-07 31.2 1.1 0.011 16.1 0.0 2.8 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 RLN15065.1 - 3.6e-07 29.8 2.5 0.023 14.4 0.8 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 RLN15065.1 - 9.2e-07 29.0 0.0 0.086 12.6 0.0 3.5 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN15065.1 - 1.1e-06 28.6 0.1 0.0078 16.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase PDR_CDR PF06422.12 RLN15065.1 - 2.5e-06 27.3 0.0 0.00023 21.0 0.0 3.1 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 RLN15065.1 - 3.4e-06 26.4 41.0 9.9e-06 24.9 23.6 3.9 3 1 1 4 4 4 2 ABC-2 family transporter protein AAA_22 PF13401.6 RLN15065.1 - 0.00013 22.2 0.1 0.38 11.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN15065.1 - 0.00098 18.5 0.2 0.21 10.8 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 RLN15065.1 - 0.0016 18.1 0.9 0.72 9.4 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RLN15065.1 - 0.0019 18.7 0.8 0.3 11.6 0.3 2.3 2 0 0 2 2 2 1 AAA domain PDR_assoc PF08370.11 RLN15065.1 - 0.0023 17.6 15.2 0.0026 17.5 0.3 3.4 4 0 0 4 4 3 2 Plant PDR ABC transporter associated AAA_30 PF13604.6 RLN15065.1 - 0.003 17.3 0.1 1.7 8.3 0.1 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 RLN15065.1 - 0.0049 16.3 1.6 19 4.6 0.0 4.0 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain DUF4705 PF15788.5 RLN15065.1 - 0.0061 16.8 1.7 0.017 15.4 1.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4705) AAA_18 PF13238.6 RLN15065.1 - 0.014 16.0 0.2 6.4 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 RLN15065.1 - 0.027 14.1 1.4 1.8 8.2 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 RLN15065.1 - 0.042 14.3 0.7 13 6.2 0.1 3.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 RLN15065.1 - 0.043 14.0 0.1 5.1 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 RLN15065.1 - 0.052 13.6 0.3 16 5.6 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_19 PF13245.6 RLN15065.1 - 0.17 12.2 0.2 25 5.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RLN15065.1 - 0.4 10.6 6.4 5.6 6.9 0.5 2.6 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.17 RLN15065.1 - 0.75 9.9 3.5 18 5.3 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_24 PF13479.6 RLN15065.1 - 1.1 9.0 2.1 16 5.2 0.5 2.3 2 0 0 2 2 2 0 AAA domain PDEase_I PF00233.19 RLN15071.1 - 6.9e-64 215.8 0.0 1e-63 215.2 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 RLN15071.1 - 1.2e-08 35.7 0.2 1.5e-07 32.1 0.0 2.9 3 0 0 3 3 3 1 GAF domain GAF_2 PF13185.6 RLN15071.1 - 2.7e-06 27.7 0.8 3.3e-05 24.2 0.0 2.9 3 0 0 3 3 3 1 GAF domain TetR_C_30 PF17939.1 RLN15071.1 - 0.18 12.0 2.7 5.7 7.2 0.0 4.0 5 0 0 5 5 5 0 Tetracyclin repressor-like, C-terminal domain Carn_acyltransf PF00755.20 RLN15072.1 - 3.4e-125 418.9 0.0 3.9e-125 418.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CD36 PF01130.21 RLN15073.1 - 5.2e-21 74.7 0.0 1.2e-15 57.0 0.0 3.2 2 1 0 2 2 2 2 CD36 family T3SS_needle_F PF09392.10 RLN15073.1 - 0.12 12.6 0.4 0.42 10.9 0.4 2.0 1 0 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF DUF3185 PF11381.8 RLN15073.1 - 0.5 10.4 1.9 15 5.7 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) TRP PF06011.12 RLN15076.1 - 2.9e-11 42.8 5.0 5.3e-09 35.3 0.0 2.3 2 0 0 2 2 2 2 Transient receptor potential (TRP) ion channel DUF1282 PF06930.12 RLN15076.1 - 0.021 14.6 0.2 0.021 14.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) IML1 PF12257.8 RLN15080.1 - 1.3e-87 293.5 0.0 2.5e-87 292.6 0.0 1.5 1 1 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 Telethonin PF09470.10 RLN15080.1 - 0.095 12.6 0.1 0.28 11.0 0.1 1.8 1 0 0 1 1 1 0 Telethonin protein RPA_interact_N PF14766.6 RLN15081.1 - 1.4e-10 40.6 4.5 2.8e-10 39.6 4.5 1.5 1 0 0 1 1 1 1 Replication protein A interacting N-terminal RPA_interact_M PF14767.6 RLN15081.1 - 1.1 9.9 8.6 2.4 8.8 8.6 1.7 1 1 0 1 1 1 0 Replication protein A interacting middle NAD_Gly3P_dh_C PF07479.14 RLN15082.1 - 1.3e-39 135.7 0.0 2.3e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 RLN15082.1 - 1e-34 119.8 0.0 1.4e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 RLN15082.1 - 2e-08 34.7 0.1 4.8e-08 33.5 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 RLN15082.1 - 2.5e-05 23.9 0.0 4.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 RLN15082.1 - 3.2e-05 24.1 0.0 5.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 RLN15082.1 - 0.00055 19.9 0.4 0.0014 18.5 0.4 1.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 RLN15082.1 - 0.0039 16.8 0.0 0.0091 15.6 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.6 RLN15082.1 - 0.011 15.6 0.1 0.022 14.6 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H-binding 2-Hacid_dh_C PF02826.19 RLN15082.1 - 0.015 14.7 0.1 0.23 10.8 0.1 2.3 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN15082.1 - 0.032 13.5 0.4 0.067 12.5 0.3 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_transf_4 PF13439.6 RLN15082.1 - 0.11 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Rossmann-like PF10727.9 RLN15082.1 - 0.28 11.1 2.6 0.97 9.3 2.6 1.9 1 1 0 1 1 1 0 Rossmann-like domain UBA_4 PF14555.6 RLN15083.1 - 9.6e-06 25.3 0.0 0.014 15.2 0.0 2.5 2 0 0 2 2 2 2 UBA-like domain DUF724 PF05266.14 RLN15084.1 - 0.4 10.5 1.2 0.6 9.9 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DAGAT PF03982.13 RLN15085.1 - 1.1e-32 113.1 0.0 1.5e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Fib_alpha PF08702.10 RLN15087.1 - 0.16 12.1 4.1 3.4 7.9 0.9 3.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family ATG16 PF08614.11 RLN15087.1 - 0.41 10.8 10.2 0.061 13.6 5.7 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Cep57_MT_bd PF06657.13 RLN15087.1 - 0.46 11.0 6.9 4.1 7.9 1.0 3.5 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Neocarzinostat PF00960.18 RLN15088.1 - 0.011 15.7 0.2 0.024 14.6 0.2 1.5 1 0 0 1 1 1 0 Neocarzinostatin family Tho2 PF11262.8 RLN15088.1 - 0.087 12.0 0.9 0.13 11.4 0.9 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 SAS4 PF15460.6 RLN15088.1 - 4.9 7.3 8.7 8.4 6.6 1.7 2.3 1 1 1 2 2 2 0 Something about silencing, SAS, complex subunit 4 SKA2 PF16740.5 RLN15089.1 - 0.49 10.2 7.9 0.16 11.7 0.9 2.7 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DnaJ PF00226.31 RLN15090.1 - 4.8e-23 81.0 3.3 9.6e-23 80.1 2.6 2.0 2 0 0 2 2 1 1 DnaJ domain TPR_2 PF07719.17 RLN15090.1 - 4.8e-16 57.5 9.6 0.0054 16.7 0.0 7.6 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 RLN15090.1 - 1.2e-13 50.2 2.5 0.004 16.9 0.0 7.1 6 2 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 RLN15090.1 - 1.1e-09 38.6 14.6 0.0013 19.2 0.8 5.3 3 2 2 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN15090.1 - 6e-08 32.2 0.7 0.0022 17.7 0.0 5.1 5 0 0 5 5 5 1 TPR repeat TPR_8 PF13181.6 RLN15090.1 - 1e-06 28.4 8.9 2.2 8.7 0.1 7.7 7 2 1 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN15090.1 - 3.3e-05 24.3 20.3 1.2 10.1 0.0 6.8 4 2 4 8 8 7 3 Tetratricopeptide repeat DUF3856 PF12968.7 RLN15090.1 - 0.00011 22.2 2.8 0.0064 16.6 0.8 3.2 2 1 1 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_16 PF13432.6 RLN15090.1 - 0.00014 22.4 15.5 0.23 12.2 0.5 5.4 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN15090.1 - 0.0023 18.0 11.3 0.44 10.7 0.1 4.6 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN15090.1 - 0.0025 17.7 3.2 11 6.4 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN15090.1 - 0.0028 17.9 20.0 0.74 10.1 1.3 4.7 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN15090.1 - 0.0042 17.4 0.6 0.38 11.2 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN15090.1 - 0.067 13.1 9.0 13 5.8 0.2 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat DHC_N2 PF08393.13 RLN15090.1 - 0.068 12.3 1.8 0.086 11.9 1.8 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 SesA PF17107.5 RLN15090.1 - 0.16 12.2 1.0 0.89 9.8 0.5 2.4 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF627 PF04781.12 RLN15090.1 - 0.46 10.5 6.1 0.48 10.5 1.9 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF627) Dimer_Tnp_hAT PF05699.14 RLN15093.1 - 0.00035 20.3 0.1 0.0022 17.7 0.0 2.2 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region EF-hand_7 PF13499.6 RLN15095.1 - 2.6e-26 91.8 3.7 7.3e-09 36.0 0.5 5.0 3 1 2 5 5 5 4 EF-hand domain pair EF-hand_1 PF00036.32 RLN15095.1 - 1.4e-22 77.5 12.1 0.0003 20.1 0.4 5.6 5 0 0 5 5 5 5 EF hand EF-hand_5 PF13202.6 RLN15095.1 - 2.4e-18 64.7 9.6 0.00023 20.5 0.0 5.5 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 RLN15095.1 - 9.6e-18 62.6 13.0 0.0005 19.8 0.2 5.8 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 RLN15095.1 - 7.9e-13 48.1 5.8 0.021 14.7 0.0 5.8 4 1 1 5 5 5 4 EF-hand domain pair WD40 PF00400.32 RLN15095.1 - 1.2e-05 25.9 5.4 2.4 9.2 0.0 6.5 7 0 0 7 7 7 2 WD domain, G-beta repeat EF-hand_4 PF12763.7 RLN15095.1 - 0.00025 21.0 3.3 0.019 14.9 0.0 3.7 3 1 1 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 RLN15095.1 - 0.00031 21.0 4.9 0.095 13.0 0.0 4.6 5 0 0 5 5 5 2 EF-hand domain PriCT_1 PF08708.11 RLN15095.1 - 0.018 14.7 0.0 0.052 13.3 0.0 1.8 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) FYVE PF01363.21 RLN15096.1 - 0.002 18.2 13.6 0.0045 17.1 13.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN15096.1 - 0.27 11.4 6.8 0.58 10.4 6.8 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Bax1-I PF01027.20 RLN15098.1 - 2.2e-14 53.8 12.1 3.5e-13 49.9 12.1 2.0 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Pkinase PF00069.25 RLN15099.1 - 1.7e-65 221.0 0.0 2.2e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN15099.1 - 2.1e-28 99.3 0.0 4.8e-28 98.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN15099.1 - 1.9e-06 27.4 0.0 3.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Bax1-I PF01027.20 RLN15099.1 - 4.6e-05 23.4 3.8 6.1e-05 22.9 3.8 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Kdo PF06293.14 RLN15099.1 - 0.001 18.5 1.3 0.0013 18.2 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RLN15099.1 - 0.0094 14.9 0.1 0.016 14.1 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 RLN15099.1 - 0.035 12.9 0.8 0.054 12.3 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 RLN15099.1 - 0.046 13.3 0.1 0.084 12.5 0.1 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 RLN15099.1 - 0.081 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Mal_decarbox_Al PF16957.5 RLN15099.1 - 0.19 10.0 0.0 0.31 9.3 0.0 1.2 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter APH PF01636.23 RLN15099.1 - 0.23 11.3 1.5 0.7 9.8 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF2721 PF11026.8 RLN15099.1 - 4.3 7.2 5.7 0.84 9.5 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) AAA PF00004.29 RLN15100.1 - 3.1e-85 283.2 0.0 1.2e-47 161.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 RLN15100.1 - 8.6e-21 73.9 3.7 1e-20 73.7 2.0 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.17 RLN15100.1 - 3e-14 52.6 0.0 6.5e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 RuvB_N PF05496.12 RLN15100.1 - 3.7e-14 52.8 0.0 6.2e-06 26.0 0.0 3.1 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 RLN15100.1 - 2.3e-13 50.6 0.0 3.4e-06 27.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 RLN15100.1 - 1.1e-12 48.7 0.3 0.00014 22.3 0.0 3.9 2 2 1 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 RLN15100.1 - 2.1e-12 46.6 0.7 5.8e-12 45.2 0.7 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_33 PF13671.6 RLN15100.1 - 1.1e-11 45.1 0.0 8.2e-06 26.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 RLN15100.1 - 3.3e-11 43.4 0.1 6.3e-06 26.2 0.0 3.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RLN15100.1 - 5e-11 43.0 0.3 0.05 13.9 0.0 4.6 3 2 2 5 5 4 2 AAA domain TIP49 PF06068.13 RLN15100.1 - 1.2e-08 34.6 0.0 0.0006 19.1 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 RLN15100.1 - 5.7e-08 32.9 0.0 0.0023 17.9 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 RLN15100.1 - 2.5e-07 31.3 0.0 0.031 14.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 RLN15100.1 - 4.2e-07 30.3 0.0 0.012 16.0 0.0 3.0 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.21 RLN15100.1 - 4.6e-07 29.4 0.1 0.035 13.5 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 RLN15100.1 - 2.2e-06 27.4 0.3 1.7 8.2 0.0 3.7 2 1 1 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 RLN15100.1 - 2.4e-06 27.5 0.0 0.0049 16.6 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 RLN15100.1 - 4.3e-06 26.6 0.1 0.11 12.2 0.0 2.7 2 1 0 2 2 2 2 IstB-like ATP binding protein ATPase PF06745.13 RLN15100.1 - 5.1e-06 26.0 0.1 1.9 7.8 0.0 3.4 3 0 0 3 3 3 2 KaiC ATPase_2 PF01637.18 RLN15100.1 - 5.7e-06 26.4 0.1 0.15 11.9 0.0 3.0 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_17 PF13207.6 RLN15100.1 - 1.3e-05 25.7 0.0 0.085 13.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.18 RLN15100.1 - 1.6e-05 24.9 0.0 0.045 13.6 0.0 2.3 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_7 PF12775.7 RLN15100.1 - 1.8e-05 24.3 0.0 0.13 11.8 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region ABC_tran PF00005.27 RLN15100.1 - 2e-05 25.1 0.0 0.15 12.6 0.0 3.2 3 1 0 3 3 2 2 ABC transporter NACHT PF05729.12 RLN15100.1 - 4.2e-05 23.5 0.0 0.69 9.8 0.0 3.6 3 1 0 4 4 4 2 NACHT domain AAA_28 PF13521.6 RLN15100.1 - 5.4e-05 23.5 0.0 0.27 11.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 RLN15100.1 - 6.7e-05 22.6 0.0 0.45 10.2 0.0 3.3 2 1 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 RLN15100.1 - 8.6e-05 21.9 0.0 0.47 9.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_24 PF13479.6 RLN15100.1 - 8.6e-05 22.3 0.0 0.15 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 RLN15100.1 - 9e-05 22.5 0.0 0.56 10.2 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 RLN15100.1 - 0.00012 21.2 0.0 0.26 10.3 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 RLN15100.1 - 0.00017 20.9 0.0 0.34 10.1 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Cytidylate_kin2 PF13189.6 RLN15100.1 - 0.00041 20.5 0.1 0.24 11.5 0.0 2.8 3 0 0 3 3 3 1 Cytidylate kinase-like family Sigma54_activ_2 PF14532.6 RLN15100.1 - 0.00056 20.0 0.0 0.34 11.0 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 RLN15100.1 - 0.00091 19.1 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 RLN15100.1 - 0.0012 18.1 0.0 0.45 9.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ResIII PF04851.15 RLN15100.1 - 0.0012 18.9 0.0 0.076 13.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 RLN15100.1 - 0.0025 17.8 0.7 3.7 7.4 0.0 4.0 3 1 0 4 4 4 0 NTPase DUF2075 PF09848.9 RLN15100.1 - 0.003 16.9 0.0 0.76 9.0 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 RLN15100.1 - 0.0039 16.7 3.5 1.5 8.2 0.0 3.1 3 0 0 3 3 3 1 PhoH-like protein AAA_19 PF13245.6 RLN15100.1 - 0.0054 17.1 2.3 7.3 6.9 0.1 4.0 4 1 0 5 5 4 0 AAA domain Rad17 PF03215.15 RLN15100.1 - 0.0062 16.5 0.0 1.8 8.5 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 RLN15100.1 - 0.0077 16.0 0.2 5.3 6.7 0.1 3.2 3 0 0 3 3 3 0 AAA domain UFD1 PF03152.14 RLN15100.1 - 0.0096 15.4 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 SKI PF01202.22 RLN15100.1 - 0.014 15.5 0.1 7.6 6.6 0.0 2.9 3 0 0 3 3 2 0 Shikimate kinase AAA_11 PF13086.6 RLN15100.1 - 0.016 15.0 0.0 7.1 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 RLN15100.1 - 0.023 14.4 0.0 6 6.5 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase Zot PF05707.12 RLN15100.1 - 0.045 13.4 0.0 1 9.0 0.0 2.6 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) TniB PF05621.11 RLN15100.1 - 0.052 12.9 0.0 11 5.4 0.0 3.3 3 0 0 3 3 3 0 Bacterial TniB protein AAA_29 PF13555.6 RLN15100.1 - 0.053 13.3 0.0 5.5 6.8 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain KAP_NTPase PF07693.14 RLN15100.1 - 0.07 12.4 0.1 2.2 7.5 0.0 2.9 2 2 2 4 4 3 0 KAP family P-loop domain PduV-EutP PF10662.9 RLN15100.1 - 0.14 11.9 0.0 4.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AFG1_ATPase PF03969.16 RLN15100.1 - 0.9 8.4 2.6 12 4.7 0.0 2.8 3 0 0 3 3 3 0 AFG1-like ATPase Dus PF01207.17 RLN15101.1 - 1.2e-32 113.3 0.1 2e-27 96.1 0.2 3.6 2 2 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-C2H2_jaz PF12171.8 RLN15101.1 - 3.6e-05 23.9 1.3 3.6e-05 23.9 1.3 2.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RLN15101.1 - 0.0001 22.6 0.9 0.0001 22.6 0.9 1.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 RLN15101.1 - 0.0025 17.5 0.9 0.0042 16.8 0.1 1.8 2 0 0 2 2 2 1 U1 zinc finger AKAP95 PF04988.12 RLN15101.1 - 0.014 15.6 0.2 0.029 14.6 0.2 1.5 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-DBF PF07535.12 RLN15101.1 - 0.093 12.9 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_2 PF12756.7 RLN15101.1 - 0.12 12.7 1.9 0.23 11.8 0.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) PEP_mutase PF13714.6 RLN15102.1 - 6.2e-23 81.5 0.6 7.1e-23 81.3 0.6 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 RLN15102.1 - 5.6e-10 38.3 0.1 7e-10 38.0 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family AAA PF00004.29 RLN15103.1 - 3.3e-26 92.3 0.1 1e-25 90.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Macoilin PF09726.9 RLN15103.1 - 0.013 14.1 4.0 0.016 13.8 4.0 1.3 1 0 0 1 1 1 0 Macoilin family HAUS6_N PF14661.6 RLN15103.1 - 0.2 11.2 7.3 0.42 10.2 7.3 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus SfsA_N PF17746.1 RLN15104.1 - 1.1e-18 67.1 0.3 8.3e-18 64.3 0.3 2.1 1 1 0 1 1 1 1 SfsA N-terminal OB domain SfsA PF03749.13 RLN15105.1 - 2.4e-35 121.4 0.5 2.3e-34 118.3 0.5 1.9 1 1 0 1 1 1 1 Sugar fermentation stimulation protein RE domain Nitroreductase PF00881.24 RLN15106.1 - 4.4e-26 92.0 0.0 5.6e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Cu-oxidase_2 PF07731.14 RLN15107.1 - 5.2e-40 136.4 2.8 1.1e-29 102.9 0.2 3.9 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN15107.1 - 6.3e-33 113.3 3.2 8.4e-31 106.5 0.4 3.9 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 RLN15107.1 - 9e-27 94.1 0.3 6.1e-26 91.4 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase DUF3881 PF12997.7 RLN15107.1 - 0.24 10.6 0.0 0.4 9.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) PAP2 PF01569.21 RLN15108.1 - 0.077 12.8 5.9 0.05 13.4 3.7 1.7 1 1 0 1 1 1 0 PAP2 superfamily DSPc PF00782.20 RLN15109.1 - 6.9e-08 32.4 0.2 1.1e-07 31.8 0.2 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Cu-oxidase_2 PF07731.14 RLN15111.1 - 1.3e-37 128.6 4.4 2.1e-28 98.7 0.3 4.2 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN15111.1 - 1.1e-33 115.7 3.0 3.6e-32 110.9 0.1 3.2 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 RLN15111.1 - 2.4e-27 96.0 0.0 1.1e-26 93.9 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase DUF3881 PF12997.7 RLN15111.1 - 0.2 10.8 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) Methyltr_RsmB-F PF01189.17 RLN15113.1 - 2.4e-33 115.5 0.0 1.1e-30 106.8 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F DHFR_1 PF00186.19 RLN15113.1 - 1.5e-32 112.5 0.0 2.7e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Dihydrofolate reductase zf-CCHC_2 PF13696.6 RLN15113.1 - 1.9e-05 24.4 0.2 4.9e-05 23.1 0.2 1.7 1 0 0 1 1 1 1 Zinc knuckle FtsJ PF01728.19 RLN15113.1 - 0.001 19.2 0.0 0.0044 17.1 0.0 2.0 2 1 0 2 2 2 1 FtsJ-like methyltransferase CABS1 PF15367.6 RLN15113.1 - 0.23 10.5 0.2 0.37 9.8 0.2 1.2 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 PHD PF00628.29 RLN15114.1 - 2.8e-06 27.1 5.8 5.2e-06 26.3 5.8 1.4 1 0 0 1 1 1 1 PHD-finger UPF0167 PF03691.14 RLN15114.1 - 0.056 13.2 0.8 0.1 12.4 0.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) zf-RING_2 PF13639.6 RLN15114.1 - 0.69 10.3 5.5 1.2 9.5 5.5 1.4 1 0 0 1 1 1 0 Ring finger domain ACOX PF01756.19 RLN15134.1 - 1.7e-50 171.0 0.0 2.9e-50 170.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 RLN15134.1 - 1.6e-30 106.2 1.0 2.9e-30 105.4 1.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 RLN15134.1 - 3.9e-14 52.6 0.0 1.3e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain DUF2689 PF10894.8 RLN15135.1 - 0.13 12.1 0.2 0.5 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2689) HigB-like_toxin PF05015.13 RLN15135.1 - 0.19 12.2 0.7 0.43 11.0 0.7 1.5 1 0 0 1 1 1 0 RelE-like toxin of type II toxin-antitoxin system HigB DUF3867 PF12983.7 RLN15136.1 - 0.0094 16.0 2.7 0.014 15.4 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3867) DUF4761 PF15958.5 RLN15136.1 - 0.011 15.8 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) HGAL PF15666.5 RLN15136.1 - 0.038 14.1 0.2 0.11 12.7 0.2 1.8 1 0 0 1 1 1 0 Germinal center-associated lymphoma EST1 PF10374.9 RLN15136.1 - 0.18 12.4 5.5 0.18 12.4 4.2 1.7 2 0 0 2 2 2 0 Telomerase activating protein Est1 bZIP_1 PF00170.21 RLN15136.1 - 0.25 11.5 15.2 6.3 7.0 14.9 2.3 1 1 0 1 1 1 0 bZIP transcription factor Tho2 PF11262.8 RLN15136.1 - 3 7.0 7.7 9.9 5.3 7.0 2.0 2 1 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 FYVE_2 PF02318.16 RLN15136.1 - 3.3 8.0 6.6 4.6 7.5 5.7 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger ACOX PF01756.19 RLN15137.1 - 6.6e-49 165.9 0.0 1.2e-48 165.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 RLN15137.1 - 2.1e-29 102.6 0.1 3.7e-29 101.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 RLN15137.1 - 2.3e-13 50.2 0.0 4.9e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 RLN15137.1 - 0.0072 16.5 0.1 0.02 15.1 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Abhydrolase_1 PF00561.20 RLN15138.1 - 4.6e-05 23.2 0.0 5.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 RLN15138.1 - 0.0033 17.5 0.0 0.0044 17.1 0.0 1.2 1 0 0 1 1 1 1 TAP-like protein Sulfate_transp PF00916.20 RLN15139.1 - 2.1e-16 59.6 17.6 2.1e-16 59.6 17.6 2.6 1 1 1 2 2 2 1 Sulfate permease family STAS PF01740.21 RLN15139.1 - 1.7e-07 30.9 0.1 3.3e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 RLN15139.1 - 0.00017 22.0 20.6 0.0031 17.9 3.9 3.3 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Myb_DNA-binding PF00249.31 RLN15140.1 - 4e-09 36.5 0.0 7.7e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN15140.1 - 0.068 13.4 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Arrestin_C PF02752.22 RLN15141.1 - 3e-15 56.8 0.0 9.8e-12 45.5 0.0 2.7 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 RLN15141.1 - 1.1e-12 48.2 0.1 3e-10 40.4 0.0 2.7 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 RLN15141.1 - 0.034 13.8 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like Tenui_NCP PF04876.12 RLN15141.1 - 0.084 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein Patatin PF01734.22 RLN15142.1 - 3.5e-05 24.1 0.0 4.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase Myb_DNA-binding PF00249.31 RLN15143.1 - 4.1e-09 36.5 0.0 7.3e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain COX6B PF02297.17 RLN15145.1 - 0.039 14.2 0.6 0.087 13.1 0.6 1.5 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb UPF0203 PF05254.12 RLN15145.1 - 0.055 13.7 1.0 0.11 12.7 1.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) FRQ PF09421.10 RLN15146.1 - 0.022 12.8 4.4 0.026 12.6 4.4 1.0 1 0 0 1 1 1 0 Frequency clock protein FCP1_C PF09309.10 RLN15146.1 - 0.084 12.7 5.2 0.11 12.4 5.2 1.1 1 0 0 1 1 1 0 FCP1, C-terminal CENP-B_dimeris PF09026.10 RLN15146.1 - 0.15 12.5 4.9 0.23 11.9 4.9 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4637 PF15470.6 RLN15146.1 - 0.48 10.1 2.6 0.63 9.8 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) NOA36 PF06524.12 RLN15146.1 - 0.55 9.5 3.0 0.76 9.0 3.0 1.1 1 0 0 1 1 1 0 NOA36 protein Baculo_PEP_C PF04513.12 RLN15147.1 - 0.0096 16.0 0.2 0.01 15.9 0.2 1.0 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 RLN15147.1 - 0.041 14.0 0.5 0.046 13.8 0.5 1.0 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Scm3 PF10384.9 RLN15147.1 - 0.041 13.6 0.0 0.052 13.3 0.0 1.1 1 0 0 1 1 1 0 Centromere protein Scm3 LppA PF16708.5 RLN15147.1 - 0.042 13.8 1.0 0.04 13.9 1.0 1.0 1 0 0 1 1 1 0 Lipoprotein confined to pathogenic Mycobacterium DUF948 PF06103.11 RLN15147.1 - 0.091 13.0 0.9 0.096 13.0 0.9 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Snf7 PF03357.21 RLN15147.1 - 0.12 12.0 7.7 0.12 11.9 7.7 1.0 1 0 0 1 1 1 0 Snf7 COMP PF11598.8 RLN15147.1 - 0.17 12.4 2.2 0.31 11.5 1.8 1.6 1 1 1 2 2 2 0 Cartilage oligomeric matrix protein HalX PF08663.10 RLN15147.1 - 0.3 11.4 4.9 2.1 8.7 4.9 1.9 1 1 0 1 1 1 0 HalX domain Pkinase PF00069.25 RLN15148.1 - 2.8e-36 125.2 0.0 7.9e-26 91.0 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN15148.1 - 1.9e-16 60.1 0.0 1.6e-09 37.4 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase ATG11 PF10377.9 RLN15148.1 - 1.1e-14 54.5 0.0 7.4e-07 29.3 0.0 3.6 3 1 1 4 4 4 2 Autophagy-related protein 11 ABC1 PF03109.16 RLN15148.1 - 0.0014 18.8 0.0 0.0035 17.5 0.0 1.6 1 0 0 1 1 1 1 ABC1 family zf-RRN7 PF11781.8 RLN15148.1 - 0.022 14.4 0.8 0.022 14.4 0.8 2.1 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Baculo_RING PF05883.11 RLN15148.1 - 3.6 7.6 6.5 0.17 11.8 0.3 2.0 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-RRN7 PF11781.8 RLN15150.1 - 0.0063 16.2 0.8 0.0063 16.2 0.8 2.6 2 0 0 2 2 2 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 4HBT PF03061.22 RLN15175.1 - 8.6e-10 38.8 0.3 8e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily MaoC_dehydratas PF01575.19 RLN15175.1 - 0.086 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain MULE PF10551.9 RLN15176.1 - 0.0022 18.3 0.0 0.0055 17.1 0.0 1.6 2 0 0 2 2 2 1 MULE transposase domain Pkinase PF00069.25 RLN15183.1 - 1.4e-47 162.3 0.0 1.8e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN15183.1 - 5.7e-43 147.1 0.0 8.1e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Podoplanin PF05808.11 RLN15183.1 - 0.026 14.6 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 Podoplanin EphA2_TM PF14575.6 RLN15183.1 - 0.14 13.1 0.0 0.3 12.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MtrF PF09472.10 RLN15183.1 - 0.7 9.3 3.5 1.7 8.1 3.5 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF547 PF04784.14 RLN15184.1 - 9.4e-10 38.6 0.0 2.2e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF547 TFIIE-A_C PF11521.8 RLN15184.1 - 2 8.7 6.6 0.39 11.0 1.9 2.1 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Pkinase PF00069.25 RLN15185.1 - 3.2e-49 167.7 0.0 4.3e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN15185.1 - 1.9e-44 151.9 0.0 2.6e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Podoplanin PF05808.11 RLN15185.1 - 0.0013 18.9 0.5 0.0026 17.9 0.5 1.5 1 0 0 1 1 1 1 Podoplanin EphA2_TM PF14575.6 RLN15185.1 - 0.0028 18.5 0.0 0.0052 17.6 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF1180 PF06679.12 RLN15185.1 - 0.071 13.5 0.2 0.12 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Haspin_kinase PF12330.8 RLN15185.1 - 0.12 11.3 0.1 0.31 10.0 0.1 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Rax2 PF12768.7 RLN15185.1 - 0.17 11.3 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity TMEM154 PF15102.6 RLN15185.1 - 0.2 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Adeno_E3_CR2 PF02439.15 RLN15185.1 - 0.43 10.4 3.4 0.8 9.5 3.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pkinase PF00069.25 RLN15186.1 - 8.1e-40 136.8 0.0 1.2e-39 136.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN15186.1 - 6.3e-36 124.0 0.0 1.8e-35 122.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_16 PF13432.6 RLN15187.1 - 0.00057 20.5 4.7 0.00057 20.5 4.7 5.2 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN15187.1 - 0.002 18.6 20.9 0.11 13.0 3.1 5.3 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN15187.1 - 0.0069 16.5 1.4 1.6 9.2 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN15187.1 - 0.013 15.2 1.0 4.4 7.3 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 RLN15187.1 - 0.017 15.1 4.3 8.9 6.6 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN15187.1 - 0.022 15.0 10.9 2.2 8.6 0.2 4.8 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 RLN15187.1 - 0.065 13.6 0.9 3.3 8.3 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RHH_4 PF13467.6 RLN15187.1 - 0.075 12.9 0.2 22 5.0 0.0 3.6 4 0 0 4 4 4 0 Ribbon-helix-helix domain TPR_2 PF07719.17 RLN15187.1 - 0.19 12.0 0.1 0.19 12.0 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 RLN15187.1 - 0.4 9.9 9.6 2.1 7.5 3.6 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 RLN15187.1 - 5 7.5 14.8 0.29 11.5 0.5 4.1 4 2 1 5 5 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 RLN15187.1 - 5.4 6.7 10.9 24 4.6 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat-like domain TPR_12 PF13424.6 RLN15187.1 - 7.8 6.9 12.4 7.6 6.9 2.9 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF1736 PF08409.11 RLN15188.1 - 4.6e-17 61.8 0.7 1.1e-16 60.5 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_1 PF00515.28 RLN15188.1 - 6.9e-11 41.5 1.3 9.7e-06 25.2 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 RLN15188.1 - 2.2e-08 33.6 7.4 5.4e-05 23.0 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN15188.1 - 2e-07 30.9 2.3 1.5 9.4 0.0 5.8 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN15188.1 - 2.6e-07 30.3 0.5 0.0041 17.2 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN15188.1 - 4.4e-07 30.1 5.8 0.0034 17.6 0.5 5.1 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN15188.1 - 4.5e-07 30.4 8.1 0.0028 18.3 0.2 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN15188.1 - 1.3e-05 24.8 1.1 0.38 10.5 0.0 4.5 5 0 0 5 5 5 2 TPR repeat TPR_19 PF14559.6 RLN15188.1 - 9.5e-05 22.8 1.6 0.061 13.8 0.1 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN15188.1 - 0.00015 22.2 0.0 0.036 14.7 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN15188.1 - 0.00059 19.9 0.1 5.7 7.2 0.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN15188.1 - 0.00084 20.0 8.1 0.33 11.9 0.0 6.5 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN15188.1 - 0.0014 18.5 1.2 0.051 13.6 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat NARP1 PF12569.8 RLN15188.1 - 0.002 17.1 0.0 0.013 14.5 0.1 1.9 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 DUF2723 PF11028.8 RLN15188.1 - 0.0077 16.2 2.0 0.022 14.7 2.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2723) PPR PF01535.20 RLN15188.1 - 0.0092 16.2 0.0 0.029 14.6 0.0 1.9 1 0 0 1 1 1 1 PPR repeat Pkinase PF00069.25 RLN15189.1 - 8.6e-48 163.0 0.0 1.2e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN15189.1 - 9.8e-44 149.6 0.0 1.2e-43 149.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RLN15189.1 - 0.061 12.3 0.2 0.19 10.6 0.2 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 RLN15190.1 - 1.2e-49 169.1 0.0 1.8e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN15190.1 - 1.5e-42 145.7 0.0 2e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RLN15190.1 - 0.0067 15.4 0.0 0.33 9.8 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain CD34_antigen PF06365.12 RLN15190.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.6 RLN15190.1 - 0.014 16.3 0.0 0.025 15.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 RLN15190.1 - 0.025 14.6 0.3 0.045 13.7 0.3 1.3 1 0 0 1 1 1 0 Protocadherin Podoplanin PF05808.11 RLN15190.1 - 0.031 14.4 0.0 0.066 13.3 0.0 1.6 1 0 0 1 1 1 0 Podoplanin Adeno_E3_CR2 PF02439.15 RLN15190.1 - 0.24 11.2 1.7 0.46 10.3 1.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DAP10 PF07213.11 RLN15190.1 - 0.41 10.6 2.5 0.27 11.2 0.2 1.9 2 0 0 2 2 2 0 DAP10 membrane protein DUF3430 PF11912.8 RLN15190.1 - 0.61 10.1 12.6 0.18 11.8 3.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3430) Pkinase PF00069.25 RLN15191.1 - 2e-51 174.9 0.0 2.8e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN15191.1 - 1.7e-44 152.0 0.0 2.3e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Uroplakin_II PF07353.12 RLN15191.1 - 0.011 15.3 0.1 0.07 12.6 0.0 2.1 2 0 0 2 2 2 0 Uroplakin II DUF3325 PF11804.8 RLN15191.1 - 0.079 13.1 2.4 1 9.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) Haspin_kinase PF12330.8 RLN15191.1 - 0.09 11.7 0.1 0.29 10.1 0.1 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Zip PF02535.22 RLN15191.1 - 0.094 11.9 0.1 0.42 9.8 0.0 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter Pkinase_Tyr PF07714.17 RLN15192.1 - 2.9e-15 56.3 0.0 3.4e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN15192.1 - 2.6e-12 46.7 0.0 3.4e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 RLN15192.1 - 0.024 15.5 0.0 0.034 15.0 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 RLN15192.1 - 0.042 13.8 0.2 0.064 13.2 0.2 1.2 1 0 0 1 1 1 0 Protocadherin ABC2_membrane PF01061.24 RLN15209.1 - 2.4e-45 154.6 45.9 4.3e-29 101.4 27.5 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN15209.1 - 1.3e-33 116.5 0.0 1.2e-16 61.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 RLN15209.1 - 2.7e-07 30.6 0.2 0.0008 19.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 RLN15209.1 - 8.1e-07 28.7 0.8 0.0053 16.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN15209.1 - 1.3e-05 25.5 0.0 0.18 12.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 RLN15209.1 - 7.6e-05 22.4 0.5 0.35 10.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 RLN15209.1 - 7.7e-05 22.6 0.1 2.3 8.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 RLN15209.1 - 0.00017 21.7 0.1 0.75 9.9 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 RLN15209.1 - 0.00019 22.0 0.1 1.1 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RLN15209.1 - 0.00037 21.0 1.1 0.49 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 RLN15209.1 - 0.00057 20.1 0.0 0.45 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN15209.1 - 0.00097 19.6 0.0 1.2 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 RLN15209.1 - 0.0012 19.3 0.7 2 8.8 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 RLN15209.1 - 0.0024 17.6 3.5 1 9.0 0.2 2.3 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 RLN15209.1 - 0.013 15.8 0.4 0.6 10.3 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RLN15209.1 - 0.018 14.8 1.3 1.7 8.3 0.2 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 RLN15209.1 - 0.033 14.2 1.4 1.5 8.8 0.2 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 RLN15209.1 - 0.042 14.2 0.5 15 6.1 0.0 3.0 3 0 0 3 3 2 0 RNA helicase MeaB PF03308.16 RLN15209.1 - 0.051 12.6 0.4 6.6 5.6 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 RLN15209.1 - 0.055 12.7 2.4 5.1 6.3 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 RLN15209.1 - 0.083 12.8 2.4 3.6 7.5 0.4 2.4 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 RLN15209.1 - 0.084 12.5 2.2 6 6.4 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 RLN15209.1 - 0.17 12.3 0.3 7.3 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 RLN15209.1 - 0.18 11.2 0.1 20 4.6 0.0 3.1 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain NTPase_1 PF03266.15 RLN15209.1 - 0.22 11.4 2.0 6.9 6.6 0.0 2.7 3 0 0 3 3 3 0 NTPase PRK PF00485.18 RLN15209.1 - 0.22 11.2 0.3 19 4.9 0.2 3.0 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family PDR_assoc PF08370.11 RLN15209.1 - 0.58 9.9 7.9 0.058 13.1 2.2 2.3 2 0 0 2 2 2 0 Plant PDR ABC transporter associated AAA_19 PF13245.6 RLN15209.1 - 0.65 10.3 2.8 5.6 7.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 RLN15209.1 - 4.7 7.2 5.4 21 5.1 0.3 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Glyco_hydro_17 PF00332.18 RLN15210.1 - 3.3e-06 26.9 2.5 2.5e-05 24.1 0.3 2.4 2 1 1 3 3 3 1 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.13 RLN15210.1 - 0.0025 16.8 0.5 0.0055 15.7 0.5 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 DUF823 PF05689.11 RLN15210.1 - 0.26 11.0 2.8 1.6 8.5 0.0 2.6 2 1 0 2 2 2 0 Salmonella repeat of unknown function (DUF823) FAM76 PF16046.5 RLN15211.1 - 4.3 6.6 7.7 1 8.7 0.5 2.2 2 0 0 2 2 2 0 FAM76 protein LUC7 PF03194.15 RLN15212.1 - 3.4e-73 246.4 3.6 4.4e-73 246.0 3.6 1.1 1 0 0 1 1 1 1 LUC7 N_terminus zf_C2H2_13 PF18508.1 RLN15212.1 - 0.018 14.6 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 Zinc finger domain SMBP PF16785.5 RLN15212.1 - 0.16 12.2 2.8 0.14 12.4 1.5 1.6 1 1 0 1 1 1 0 Small metal-binding protein AAA_13 PF13166.6 RLN15212.1 - 0.32 9.6 4.2 0.3 9.7 2.5 1.6 2 0 0 2 2 2 0 AAA domain HBS1_N PF08938.10 RLN15212.1 - 2.2 8.6 6.5 6.5 7.1 5.9 2.0 2 0 0 2 2 2 0 HBS1 N-terminus Peptidase_C2 PF00648.21 RLN15213.1 - 1.6e-53 181.7 0.0 2.3e-53 181.2 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease WW PF00397.26 RLN15213.1 - 5.7e-09 35.9 0.4 1.9e-08 34.3 0.4 1.9 1 0 0 1 1 1 1 WW domain C2 PF00168.30 RLN15213.1 - 6.5e-09 36.0 0.0 1.6e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF5337 PF17272.2 RLN15213.1 - 7.7 6.4 11.6 16 5.4 5.2 3.3 2 0 0 2 2 2 0 Family of unknown function (DUF5337) DUF997 PF06196.12 RLN15213.1 - 8.5 6.5 14.7 0.11 12.5 3.2 4.0 2 1 0 2 2 2 0 Protein of unknown function (DUF997) LCM PF04072.14 RLN15214.1 - 1.6e-14 54.3 0.0 3.4e-14 53.2 0.0 1.5 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Asp PF00026.23 RLN15215.1 - 9e-07 28.6 0.0 1.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Atg14 PF10186.9 RLN15215.1 - 0.00027 20.1 6.0 0.00036 19.7 6.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 PolC_DP2 PF03833.13 RLN15215.1 - 1.3 6.8 3.6 1.6 6.5 3.6 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Tub PF01167.18 RLN15216.1 - 1.1e-50 172.6 0.2 2.2e-50 171.6 0.2 1.5 1 0 0 1 1 1 1 Tub family Pkinase_Tyr PF07714.17 RLN15216.1 - 1.7e-36 125.8 0.0 5.5e-36 124.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RLN15216.1 - 3.9e-31 108.4 0.0 1.3e-30 106.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain WD40 PF00400.32 RLN15216.1 - 1.1e-08 35.6 3.2 0.00054 20.7 0.6 6.5 5 1 1 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN15216.1 - 1.7e-07 31.4 0.2 0.3 11.4 0.1 5.4 1 1 5 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 RLN15216.1 - 0.016 15.1 1.1 43 4.0 0.0 4.1 1 1 3 4 4 4 0 Region in Clathrin and VPS PQQ_2 PF13360.6 RLN15216.1 - 0.02 14.5 0.7 0.069 12.7 0.7 1.9 1 0 0 1 1 1 0 PQQ-like domain WD40_like PF17005.5 RLN15216.1 - 0.027 13.8 0.0 0.46 9.8 0.0 2.5 3 0 0 3 3 3 0 WD40-like domain Kinase-like PF14531.6 RLN15216.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SRA1 PF07304.11 RLN15216.1 - 0.21 11.4 0.0 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) TPR_2 PF07719.17 RLN15216.1 - 1.4 9.2 13.3 2 8.7 0.5 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN15216.1 - 2.7 7.9 5.6 24 5.0 0.5 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 RLN15216.1 - 3 8.1 6.5 24 5.3 0.1 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat MatE PF01554.18 RLN15217.1 - 4.2e-38 130.5 35.8 5e-19 68.5 13.7 2.3 2 0 0 2 2 2 2 MatE MatE PF01554.18 RLN15218.1 - 4.8e-40 136.8 34.1 5.2e-21 75.0 13.0 2.3 2 0 0 2 2 2 2 MatE OST3_OST6 PF04756.13 RLN15218.1 - 0.27 10.5 2.2 0.4 10.0 0.8 1.9 1 1 1 2 2 2 0 OST3 / OST6 family, transporter family Kelch_1 PF01344.25 RLN15219.1 - 8.1e-63 207.8 0.5 4.8e-14 51.7 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RLN15219.1 - 1.1e-44 149.4 0.0 6.2e-10 39.0 0.0 6.3 4 1 2 6 6 6 5 Kelch motif Kelch_4 PF13418.6 RLN15219.1 - 1.5e-33 114.5 0.0 3.5e-06 26.9 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 RLN15219.1 - 4.9e-27 92.8 0.9 4.1e-05 23.4 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 RLN15219.1 - 3.4e-24 84.6 1.2 4.6e-06 26.8 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain BTB PF00651.31 RLN15219.1 - 5.9e-22 78.0 0.0 1.4e-21 76.8 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.6 RLN15219.1 - 3.5e-12 46.0 3.4 0.13 12.3 0.0 6.5 6 0 0 6 6 6 4 Kelch motif BACK PF07707.15 RLN15219.1 - 9.1e-06 25.7 0.2 3.4e-05 23.9 0.2 2.0 1 1 0 1 1 1 1 BTB And C-terminal Kelch PQQ_3 PF13570.6 RLN15219.1 - 3.3 8.3 6.1 20 5.8 1.5 3.4 2 1 1 3 3 3 0 PQQ-like domain Choline_transpo PF04515.12 RLN15221.1 - 7.5e-72 242.3 23.6 7.5e-72 242.3 23.6 2.1 2 1 0 2 2 2 1 Plasma-membrane choline transporter Utp14 PF04615.13 RLN15222.1 - 1.4 7.4 8.1 1.7 7.2 8.1 1.0 1 0 0 1 1 1 0 Utp14 protein DSPc PF00782.20 RLN15226.1 - 3.2e-18 65.8 0.0 1.3e-17 63.9 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RLN15226.1 - 0.005 16.4 0.0 0.0069 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FYVE PF01363.21 RLN15227.1 - 2.6e-06 27.5 17.7 2.6e-06 27.5 17.7 2.0 2 1 0 2 2 2 1 FYVE zinc finger CDC27 PF09507.10 RLN15227.1 - 4.4 6.6 31.7 7.3 5.9 31.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ndc1_Nup PF09531.10 RLN15227.1 - 6 5.4 13.1 9.8 4.7 13.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAT PF02259.23 RLN15228.1 - 2.7e-78 263.6 0.0 5e-78 262.7 0.0 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 RLN15228.1 - 2.7e-73 246.9 0.1 4.8e-73 246.0 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 RLN15228.1 - 5.4e-46 156.4 0.6 2.6e-27 95.7 0.0 4.1 4 1 0 4 4 4 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 RLN15228.1 - 3.2e-43 146.2 0.4 3.2e-43 146.2 0.4 3.2 3 0 0 3 3 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 RLN15228.1 - 3.8e-18 65.0 0.7 1.1e-17 63.6 0.7 1.8 1 0 0 1 1 1 1 FATC domain TPR_12 PF13424.6 RLN15228.1 - 0.00054 20.2 0.3 2.1 8.7 0.1 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat HEAT_2 PF13646.6 RLN15228.1 - 0.0038 17.6 30.3 0.17 12.3 1.3 9.2 9 0 0 9 9 9 2 HEAT repeats IFRD PF05004.13 RLN15228.1 - 0.0041 16.3 26.6 0.0038 16.4 5.9 4.9 6 0 0 6 6 5 2 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 RLN15228.1 - 0.0086 16.1 2.9 0.86 9.6 0.4 3.3 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Sec7_N PF12783.7 RLN15228.1 - 0.02 14.8 0.2 0.67 9.8 0.0 3.6 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT PF02985.22 RLN15228.1 - 0.078 13.3 27.9 0.2 12.0 0.0 9.0 9 0 0 9 9 8 0 HEAT repeat TPR_7 PF13176.6 RLN15228.1 - 0.79 9.9 3.5 41 4.5 0.3 4.2 3 0 0 3 3 2 0 Tetratricopeptide repeat CLASP_N PF12348.8 RLN15228.1 - 2 7.9 4.2 49 3.4 0.0 4.7 4 1 2 6 6 6 0 CLASP N terminal DUF743 PF05332.11 RLN15228.1 - 6.5 6.9 5.9 64 3.7 0.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF743) Acyl_transf_3 PF01757.22 RLN15229.1 - 2.1e-12 46.8 32.5 3.1e-12 46.2 32.5 1.3 1 0 0 1 1 1 1 Acyltransferase family CHS5_N PF16892.5 RLN15229.1 - 0.023 14.6 0.0 0.07 13.1 0.0 1.8 1 0 0 1 1 1 0 Chitin biosynthesis protein CHS5 N-terminus Peptidase_M1 PF01433.20 RLN15230.1 - 4.8e-49 166.9 0.0 6.5e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 RLN15230.1 - 1.8e-26 92.4 0.0 3.2e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 RLN15230.1 - 3.3e-21 76.3 0.0 1e-20 74.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain G-patch PF01585.23 RLN15234.1 - 4.4e-14 52.1 0.1 1.1e-13 50.8 0.1 1.7 1 0 0 1 1 1 1 G-patch domain VWA_2 PF13519.6 RLN15234.1 - 4e-08 33.9 0.0 4.2e-07 30.6 0.0 2.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 RLN15234.1 - 4.8e-07 30.2 0.0 2.3e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain DNA_pol3_delta2 PF13177.6 RLN15234.1 - 7.1e-06 25.9 0.0 1.9e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase III, delta subunit GBP PF02263.19 RLN15234.1 - 3.9e-05 23.0 0.1 0.00035 19.9 0.2 2.3 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain VPS13_C PF16909.5 RLN15234.1 - 4.9e-05 23.2 0.1 0.00011 22.1 0.1 1.5 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal G-patch_2 PF12656.7 RLN15234.1 - 6e-05 23.1 0.2 0.00022 21.3 0.2 2.0 1 0 0 1 1 1 1 G-patch domain RHD3 PF05879.12 RLN15234.1 - 9e-05 20.8 0.1 0.00018 19.9 0.1 1.4 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Rad17 PF03215.15 RLN15234.1 - 0.0014 18.6 0.0 0.004 17.1 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 RLN15234.1 - 0.0033 17.7 0.3 0.073 13.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 RLN15234.1 - 0.0042 17.5 0.0 0.014 15.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN15234.1 - 0.015 15.7 0.1 0.015 15.7 0.1 3.6 5 0 0 5 5 2 0 AAA ATPase domain Dynamin_N PF00350.23 RLN15234.1 - 0.021 14.9 1.4 0.054 13.6 0.0 2.3 2 0 0 2 2 2 0 Dynamin family Rep_fac_C PF08542.11 RLN15234.1 - 0.03 14.7 0.0 0.075 13.4 0.0 1.7 1 0 0 1 1 1 0 Replication factor C C-terminal domain AAA_24 PF13479.6 RLN15234.1 - 0.039 13.7 0.0 1.1 8.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 RLN15234.1 - 0.066 13.3 0.0 0.21 11.7 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase Resolvase PF00239.21 RLN15234.1 - 0.13 12.3 6.7 0.21 11.7 0.1 3.4 3 0 0 3 3 2 0 Resolvase, N terminal domain BssS PF13991.6 RLN15234.1 - 0.17 12.0 0.1 0.42 10.7 0.1 1.6 1 0 0 1 1 1 0 BssS protein family COesterase PF00135.28 RLN15235.1 - 2.3e-05 23.5 0.2 3.1e-05 23.1 0.2 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RLN15235.1 - 0.0012 18.7 0.1 0.002 18.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold RNA_POL_M_15KD PF02150.16 RLN15236.1 - 1.2e-05 25.0 0.3 1.2e-05 25.0 0.3 2.0 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit CpXC PF14353.6 RLN15236.1 - 0.006 16.6 1.0 0.32 11.0 0.0 2.2 2 0 0 2 2 2 1 CpXC protein TFIIS_C PF01096.18 RLN15236.1 - 0.015 15.2 2.5 0.77 9.7 0.5 2.6 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zinc_ribbon_10 PF10058.9 RLN15236.1 - 0.017 14.8 1.9 1 9.1 0.0 2.8 3 1 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn_Tnp_IS1595 PF12760.7 RLN15236.1 - 0.026 14.5 0.9 2.2 8.3 0.2 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain RNase_Zc3h12a_2 PF14626.6 RLN15236.1 - 0.031 14.5 0.0 0.04 14.1 0.0 1.2 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain Ima1_N PF09779.9 RLN15236.1 - 0.034 15.0 0.3 0.061 14.2 0.3 1.4 1 1 0 1 1 1 0 Ima1 N-terminal domain Ribosomal_S27e PF01667.17 RLN15236.1 - 0.064 13.0 0.7 0.41 10.4 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein S27 Elf1 PF05129.13 RLN15236.1 - 0.086 12.9 0.9 7 6.8 0.1 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 RLN15236.1 - 0.095 12.8 3.5 9.2 6.5 1.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-LITAF-like PF10601.9 RLN15236.1 - 0.099 12.9 1.6 0.96 9.8 0.2 2.3 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain adh_short PF00106.25 RLN15237.1 - 1.2e-62 210.9 5.7 7.7e-31 107.1 0.7 3.8 2 2 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN15237.1 - 4.7e-41 140.9 3.3 2.5e-20 73.0 0.4 3.0 2 2 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN15237.1 - 1.4e-20 73.9 0.5 3.4e-10 40.1 0.1 2.3 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 RLN15237.1 - 1.4e-11 44.4 1.2 6.9e-05 22.4 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 RLN15237.1 - 1.3e-08 34.5 0.0 0.0011 18.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.6 RLN15237.1 - 0.00027 20.9 1.2 0.17 11.8 0.3 2.8 2 1 0 2 2 2 2 NAD(P)H-binding Glyco_trans_4_2 PF13477.6 RLN15237.1 - 0.0031 17.5 0.0 3.6 7.6 0.0 2.8 3 0 0 3 3 3 2 Glycosyl transferase 4-like YjeF_N PF03853.15 RLN15237.1 - 0.012 15.5 0.5 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 YjeF-related protein N-terminus 3HCDH_N PF02737.18 RLN15237.1 - 0.026 14.4 1.2 3.2 7.6 0.2 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ecm29 PF13001.7 RLN15237.1 - 0.028 13.1 0.0 3.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Proteasome stabiliser Glyco_transf_4 PF13439.6 RLN15237.1 - 0.053 13.5 0.1 15 5.5 0.0 3.1 3 1 0 3 3 3 0 Glycosyltransferase Family 4 FlpD PF02662.16 RLN15237.1 - 0.12 12.4 0.1 11 6.0 0.0 2.7 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit FumaraseC_C PF10415.9 RLN15237.1 - 0.13 12.7 2.2 16 6.0 0.2 2.4 2 0 0 2 2 2 0 Fumarase C C-terminus GIDA PF01134.22 RLN15237.1 - 0.16 11.1 3.2 2.6 7.0 0.3 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A GDP_Man_Dehyd PF16363.5 RLN15237.1 - 0.17 11.3 0.1 9.9 5.4 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase KdpD PF02702.17 RLN15237.1 - 0.21 11.0 0.5 16 4.9 0.1 2.4 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain Asp PF00026.23 RLN15238.1 - 4.4e-22 78.9 0.0 4.9e-21 75.5 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RLN15238.1 - 7.3e-16 58.9 0.9 1.1e-15 58.3 0.9 1.2 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 RLN15238.1 - 1.2e-10 41.4 0.0 2.2e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Zip PF02535.22 RLN15239.1 - 2.7e-26 92.6 4.8 2.9e-24 85.9 4.8 2.7 1 1 0 1 1 1 1 ZIP Zinc transporter Ureide_permease PF07168.11 RLN15239.1 - 0.046 12.5 0.0 0.077 11.7 0.0 1.3 1 0 0 1 1 1 0 Ureide permease Erf4 PF10256.9 RLN15240.1 - 0.008 16.3 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family IBN_N PF03810.19 RLN15241.1 - 7.6e-07 29.0 0.4 3.9e-06 26.7 0.1 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain CRM1_C PF08767.11 RLN15241.1 - 0.0045 16.2 0.4 0.012 14.8 0.1 1.9 2 0 0 2 2 2 1 CRM1 C terminal ABC_tran PF00005.27 RLN15242.1 - 1.1e-31 110.2 0.0 2e-31 109.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 RLN15242.1 - 3.4e-20 72.8 8.9 5e-20 72.3 8.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 RLN15242.1 - 1.1e-07 31.5 0.4 4.3e-05 23.1 0.0 2.6 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain DEAD PF00270.29 RLN15242.1 - 0.0026 17.6 0.7 0.0098 15.7 0.6 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase ATP-synt_ab PF00006.25 RLN15242.1 - 0.0029 17.3 0.0 0.0058 16.3 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.6 RLN15242.1 - 0.011 16.0 1.0 0.083 13.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 RLN15242.1 - 0.014 15.5 0.2 0.038 14.1 0.2 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_18 PF13238.6 RLN15242.1 - 0.052 14.1 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 RLN15242.1 - 0.057 13.9 0.6 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain TMEM100 PF16311.5 RLN15242.1 - 0.068 12.8 0.8 0.15 11.6 0.8 1.5 1 0 0 1 1 1 0 Transmembrane protein 100 SbcCD_C PF13558.6 RLN15242.1 - 0.1 12.8 0.1 1.8 8.8 0.1 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 RLN15242.1 - 0.13 12.6 0.3 0.34 11.3 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 RLN15242.1 - 0.16 12.2 0.9 2.4 8.4 0.2 2.6 3 0 0 3 3 2 0 AAA domain AAA_21 PF13304.6 RLN15242.1 - 0.19 11.5 0.0 0.86 9.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN15242.1 - 0.32 10.7 2.6 0.27 11.0 0.6 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain adh_short PF00106.25 RLN15243.1 - 4.8e-32 111.0 0.4 3e-28 98.6 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN15243.1 - 2.2e-20 73.2 0.2 3.4e-20 72.6 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN15243.1 - 1.1e-10 41.7 0.2 1.6e-10 41.2 0.2 1.2 1 0 0 1 1 1 1 KR domain Pyr_redox_3 PF13738.6 RLN15243.1 - 0.0012 18.2 0.0 0.0028 16.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 RLN15243.1 - 0.0013 18.2 0.1 0.0017 17.8 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 RLN15243.1 - 0.015 15.2 0.8 0.032 14.1 0.8 1.6 1 1 0 1 1 1 0 NAD(P)H-binding Pox_MCEL PF03291.16 RLN15244.1 - 4.1e-48 164.2 0.0 1.1e-47 162.8 0.0 1.7 1 1 0 1 1 1 1 mRNA capping enzyme WW PF00397.26 RLN15244.1 - 1.1e-10 41.4 1.2 0.00015 21.8 0.2 2.6 2 0 0 2 2 2 2 WW domain Methyltransf_25 PF13649.6 RLN15244.1 - 4.9e-10 40.0 0.2 7.5e-08 33.0 0.2 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN15244.1 - 9.6e-08 32.0 0.0 1.9e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN15244.1 - 3.8e-07 30.8 0.0 1.2e-06 29.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN15244.1 - 4.7e-07 29.7 0.0 4.6e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN15244.1 - 3.6e-06 27.5 0.2 0.0002 21.9 0.2 2.4 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 RLN15244.1 - 0.0086 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.20 RLN15244.1 - 0.014 14.7 0.2 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase MetW PF07021.12 RLN15244.1 - 0.082 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW C2 PF00168.30 RLN15245.1 - 5.3e-07 29.9 0.0 1.4e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 C2 domain SnoaL_2 PF12680.7 RLN15245.1 - 0.023 15.4 0.1 0.08 13.6 0.1 1.9 1 1 0 1 1 1 0 SnoaL-like domain NUDIX PF00293.28 RLN15246.1 - 6.3e-15 55.4 0.0 1.5e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Bcr-Abl_Oligo PF09036.10 RLN15246.1 - 0.023 14.7 0.2 0.055 13.5 0.2 1.6 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain Ank_2 PF12796.7 RLN15247.1 - 4.3e-21 75.3 0.9 1.4e-09 38.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN15247.1 - 1.7e-16 60.3 0.7 3.6e-06 27.4 0.2 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN15247.1 - 8.8e-16 57.8 0.6 6e-08 32.8 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN15247.1 - 1.2e-13 50.8 0.1 0.032 14.7 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 RLN15247.1 - 6.1e-13 47.7 0.1 0.027 15.0 0.0 5.1 6 0 0 6 6 6 3 Ankyrin repeat DUF2064 PF09837.9 RLN15247.1 - 0.072 12.9 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) GDC-P PF02347.16 RLN15248.1 - 1.9e-05 23.7 0.0 3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage system P-protein CCDC53 PF10152.9 RLN15248.1 - 0.026 14.9 1.4 0.18 12.2 1.4 2.1 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex ENTH PF01417.20 RLN15249.1 - 1.3e-13 51.1 0.0 2.2e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 RLN15249.1 - 1.5e-07 30.7 0.0 2.4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 ANTH domain Methyltransf_24 PF13578.6 RLN15272.1 - 4.7e-12 46.9 0.1 1.6e-11 45.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.17 RLN15272.1 - 0.0071 15.5 0.1 0.011 14.9 0.1 1.3 1 1 0 1 1 1 1 O-methyltransferase Sugar_tr PF00083.24 RLN15273.1 - 1.6e-99 333.9 25.4 1.8e-99 333.7 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN15273.1 - 4.8e-27 94.8 35.2 3.8e-20 72.1 10.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 RLN15273.1 - 0.00012 20.5 1.0 0.00066 18.0 0.3 2.2 2 0 0 2 2 2 1 BT1 family DUF3054 PF11255.8 RLN15273.1 - 0.017 15.6 0.3 0.017 15.6 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3054) MFS_2 PF13347.6 RLN15273.1 - 0.096 11.2 16.5 0.013 14.0 1.8 3.1 4 1 0 4 4 4 0 MFS/sugar transport protein Rick_17kDa_Anti PF05433.15 RLN15273.1 - 5.6 6.9 7.9 0.21 11.5 0.3 2.6 3 0 0 3 3 3 0 Glycine zipper 2TM domain DUF4457 PF14652.6 RLN15274.1 - 5.8e-159 528.6 0.0 1.9e-93 313.3 0.0 3.8 2 2 1 3 3 3 3 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 RLN15274.1 - 0.0013 18.7 0.0 22 5.1 0.0 4.3 4 0 0 4 4 4 3 Sad1 / UNC-like C-terminal Pkinase PF00069.25 RLN15293.1 - 9.7e-47 159.5 0.0 1.4e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN15293.1 - 2.7e-46 158.0 0.0 3.7e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 RLN15293.1 - 3.5e-07 30.4 8.3 0.29 11.6 0.5 4.7 2 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN15293.1 - 4.1e-07 29.7 6.9 0.18 11.6 0.1 4.8 2 1 3 6 6 6 3 Leucine rich repeat FNIP PF05725.12 RLN15293.1 - 3.3e-05 23.9 0.4 0.097 12.8 0.0 3.8 3 2 0 3 3 3 1 FNIP Repeat Pkinase_fungal PF17667.1 RLN15293.1 - 0.0032 16.3 0.3 0.0068 15.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase EssA PF10661.9 RLN15293.1 - 0.02 14.8 2.6 0.056 13.3 0.4 2.4 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA LRR_6 PF13516.6 RLN15293.1 - 0.26 11.4 3.2 8.7 6.7 0.1 3.7 4 0 0 4 4 4 0 Leucine Rich repeat Plasmodium_Vir PF05795.11 RLN15293.1 - 0.4 10.1 2.3 0.55 9.6 2.3 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1180 PF06679.12 RLN15293.1 - 0.69 10.3 2.6 0.68 10.3 0.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) TTL PF03133.15 RLN15294.1 - 1.7e-71 240.7 0.1 1.7e-71 240.7 0.1 3.8 5 0 0 5 5 5 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RLN15294.1 - 2.2e-05 23.8 2.2 9e-05 21.8 0.0 2.7 3 0 0 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RLN15294.1 - 0.001 18.4 0.0 0.04 13.2 0.0 2.3 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp SR-25 PF10500.9 RLN15294.1 - 0.0061 16.2 16.7 0.0061 16.2 16.7 5.1 2 1 2 4 4 4 1 Nuclear RNA-splicing-associated protein PhoLip_ATPase_C PF16212.5 RLN15295.1 - 9e-60 202.5 21.2 9e-60 202.5 21.2 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RLN15295.1 - 1.4e-20 72.7 0.1 4.2e-20 71.2 0.1 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RLN15295.1 - 1.7e-10 41.5 0.1 0.0015 18.8 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN15295.1 - 1.3e-08 34.8 0.0 4.7e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RLN15295.1 - 2e-07 30.7 0.0 6.7e-07 29.0 0.0 1.8 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RLN15295.1 - 0.00019 21.3 0.0 0.00037 20.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Spt5_N PF11942.8 RLN15295.1 - 1.8 9.6 5.5 1.4 9.9 0.9 3.0 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal RRM_1 PF00076.22 RLN15296.1 - 1.9e-14 53.2 0.2 1.6e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RLN15296.1 - 2.9e-06 26.9 0.0 0.079 12.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 RLN15296.1 - 8.7e-06 25.6 0.1 0.00073 19.5 0.1 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 RLN15296.1 - 0.058 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Exonuc_VII_L PF02601.15 RLN15296.1 - 0.86 9.1 5.5 1.3 8.5 5.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 RLN15296.1 - 2.8 6.9 7.6 4.8 6.2 7.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sacchrp_dh_NADP PF03435.18 RLN15297.1 - 3e-15 56.6 1.0 5.9e-15 55.7 1.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Glutaredoxin PF00462.24 RLN15297.1 - 1.9e-07 31.2 1.4 1.1e-05 25.6 1.4 2.9 1 1 0 1 1 1 1 Glutaredoxin NmrA PF05368.13 RLN15297.1 - 0.0084 15.7 1.9 0.047 13.2 1.9 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 RLN15297.1 - 0.24 11.2 2.4 2.7 7.9 2.5 2.2 1 1 0 1 1 1 0 NAD(P)H-binding PX PF00787.24 RLN15298.1 - 2.6e-09 37.0 0.0 3.3e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 PX domain SLATT_fungal PF18142.1 RLN15298.1 - 0.15 12.0 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain COG6 PF06419.11 RLN15326.1 - 4.3e-132 441.5 0.0 3.1e-120 402.3 0.0 2.0 2 0 0 2 2 2 2 Conserved oligomeric complex COG6 CK2S PF15011.6 RLN15326.1 - 0.12 12.3 4.2 0.062 13.2 1.1 2.1 2 0 0 2 2 2 0 Casein Kinase 2 substrate DUF932 PF06067.11 RLN15326.1 - 0.14 11.9 3.2 0.083 12.6 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF932) Laminin_II PF06009.12 RLN15326.1 - 0.2 11.7 1.3 1.3 9.1 0.9 2.3 2 0 0 2 2 2 0 Laminin Domain II ZapB PF06005.12 RLN15326.1 - 0.27 11.7 2.5 2.5 8.6 0.2 3.2 3 0 0 3 3 3 0 Cell division protein ZapB NPV_P10 PF05531.12 RLN15326.1 - 0.39 11.2 3.3 0.57 10.7 0.9 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein LPP PF04728.13 RLN15326.1 - 1 9.8 4.1 1.1 9.7 1.0 2.8 2 0 0 2 2 2 0 Lipoprotein leucine-zipper BBP1_C PF15272.6 RLN15327.1 - 0.059 13.2 2.9 0.085 12.7 2.9 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal ADIP PF11559.8 RLN15327.1 - 0.098 12.7 7.2 0.16 12.0 7.2 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ABC_tran_CTD PF16326.5 RLN15327.1 - 0.1 12.8 1.5 0.3 11.4 0.1 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain bZIP_Maf PF03131.17 RLN15327.1 - 0.55 10.8 12.2 1.1 9.8 11.9 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor CEBP_ZZ PF16366.5 RLN15328.1 - 0.11 12.7 9.7 0.23 11.7 9.7 1.4 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-B_box PF00643.24 RLN15328.1 - 0.94 9.7 10.1 1.8 8.8 10.1 1.4 1 0 0 1 1 1 0 B-box zinc finger TPR_2 PF07719.17 RLN15329.1 - 4e-15 54.6 3.5 5.4e-05 23.0 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN15329.1 - 3.5e-13 48.8 0.6 0.00025 20.7 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN15329.1 - 5.7e-09 35.4 2.7 0.017 15.1 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN15329.1 - 3.1e-07 30.1 2.3 0.021 15.0 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN15329.1 - 3.2e-06 27.3 6.8 7.9e-05 22.9 4.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN15329.1 - 7.1e-05 22.9 3.0 0.00071 19.7 0.9 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN15329.1 - 0.00018 21.3 5.5 0.0076 16.1 0.3 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN15329.1 - 0.001 18.7 0.8 1.6 8.5 0.1 3.3 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 RLN15329.1 - 0.0016 19.0 7.9 0.016 15.8 3.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN15329.1 - 0.002 18.8 7.4 6.1 7.9 0.2 3.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN15329.1 - 0.015 15.7 0.2 11 6.7 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN15329.1 - 0.054 14.0 5.4 0.054 14.0 1.3 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN15329.1 - 7.9 7.4 7.7 37 5.2 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat DUSP PF06337.12 RLN15332.1 - 2.2e-10 41.0 0.0 3.6e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 DUSP domain PX PF00787.24 RLN15332.1 - 2.3e-10 40.4 0.2 1.8e-08 34.3 0.0 2.3 2 0 0 2 2 2 2 PX domain IQ PF00612.27 RLN15332.1 - 4.7e-06 25.9 14.6 0.005 16.5 0.9 4.0 3 0 0 3 3 3 2 IQ calmodulin-binding motif NYD-SP28 PF14772.6 RLN15333.1 - 3.1e-12 46.4 12.3 3.1e-12 46.4 12.3 4.9 3 2 2 5 5 5 1 Sperm tail NYD-SP28_assoc PF14775.6 RLN15333.1 - 3.4e-05 23.9 2.4 3.4e-05 23.9 2.4 3.5 4 0 0 4 4 4 1 Sperm tail C-terminal domain DUF948 PF06103.11 RLN15333.1 - 3.6 7.9 8.5 12 6.2 1.5 3.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) GPI-anchored PF10342.9 RLN15334.1 - 0.00024 21.8 0.0 0.0004 21.1 0.0 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ABC_tran PF00005.27 RLN15335.1 - 3.4e-45 153.9 0.0 5.5e-24 85.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 RLN15335.1 - 3.3e-29 102.4 26.4 1.3e-16 61.0 4.2 3.1 2 1 1 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 RLN15335.1 - 2.2e-09 37.1 3.3 0.039 13.4 0.1 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RLN15335.1 - 2.5e-07 30.3 1.4 0.0016 18.1 0.1 3.1 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN15335.1 - 8.4e-07 29.5 0.3 0.00015 22.2 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 RLN15335.1 - 1.4e-05 25.1 0.1 0.11 12.5 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 RLN15335.1 - 1.7e-05 24.8 5.0 0.26 11.0 0.3 4.1 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 RLN15335.1 - 1.7e-05 25.1 0.0 0.024 14.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 RLN15335.1 - 1.9e-05 24.7 0.7 0.039 13.8 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_25 PF13481.6 RLN15335.1 - 0.00016 21.3 1.1 0.043 13.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 RLN15335.1 - 0.0002 21.9 2.5 0.41 11.1 0.1 2.3 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 RLN15335.1 - 0.00038 19.9 0.7 0.048 13.0 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family cobW PF02492.19 RLN15335.1 - 0.0013 18.3 1.4 0.14 11.8 0.2 3.2 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 RLN15335.1 - 0.0014 18.2 0.1 0.099 12.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Dynamin_N PF00350.23 RLN15335.1 - 0.0024 17.9 1.3 0.47 10.5 0.1 2.8 2 0 0 2 2 2 1 Dynamin family T2SSE PF00437.20 RLN15335.1 - 0.0027 16.8 0.0 0.049 12.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.6 RLN15335.1 - 0.0032 17.6 0.2 0.061 13.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 RLN15335.1 - 0.0033 16.7 0.9 0.031 13.6 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin T6SS_VasE PF05936.12 RLN15335.1 - 0.012 14.3 0.1 0.02 13.6 0.1 1.2 1 0 0 1 1 1 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE AAA_30 PF13604.6 RLN15335.1 - 0.021 14.6 1.4 0.33 10.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 RLN15335.1 - 0.022 14.5 0.7 5.6 6.6 0.0 3.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ATP-synt_ab PF00006.25 RLN15335.1 - 0.071 12.8 0.3 2 8.0 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 RLN15335.1 - 0.076 13.6 0.4 20 5.8 0.1 2.8 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 RLN15335.1 - 0.09 11.9 0.0 8.9 5.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.17 RLN15335.1 - 0.11 12.6 4.5 5.1 7.1 0.3 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain NACHT PF05729.12 RLN15335.1 - 0.14 12.0 1.8 1.3 8.9 0.1 2.8 3 0 0 3 3 3 0 NACHT domain AAA_24 PF13479.6 RLN15335.1 - 0.15 11.8 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 RLN15335.1 - 0.19 10.5 1.0 0.72 8.6 0.5 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_15 PF13175.6 RLN15335.1 - 0.48 10.1 2.0 3.2 7.4 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain Halogen_Hydrol PF10112.9 RLN15335.1 - 1.2 9.1 4.0 11 6.0 0.1 2.9 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein TrwB_AAD_bind PF10412.9 RLN15335.1 - 2.2 7.1 5.0 2.3 7.0 0.1 2.5 3 0 0 3 3 2 0 Type IV secretion-system coupling protein DNA-binding domain TctB PF07331.11 RLN15335.1 - 8.3 6.7 18.5 0.43 10.9 5.2 3.3 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family bZIP_2 PF07716.15 RLN15338.1 - 0.033 14.3 6.0 0.073 13.2 6.0 1.5 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 RLN15338.1 - 0.081 13.0 8.2 0.13 12.4 8.2 1.3 1 0 0 1 1 1 0 bZIP transcription factor bZIP_Maf PF03131.17 RLN15338.1 - 0.2 12.2 7.4 0.36 11.4 7.4 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_Maf PF03131.17 RLN15339.1 - 0.011 16.3 6.2 0.019 15.5 6.2 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor CLZ PF16526.5 RLN15339.1 - 0.042 14.2 1.3 0.042 14.2 1.3 1.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_2 PF07716.15 RLN15339.1 - 0.075 13.1 10.2 0.17 12.0 10.2 1.6 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 RLN15339.1 - 0.19 11.9 9.6 0.35 11.0 9.6 1.4 1 0 0 1 1 1 0 bZIP transcription factor DUF5320 PF17253.2 RLN15339.1 - 0.24 12.5 1.8 0.5 11.5 1.8 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5320) PGA_cap PF09587.10 RLN15340.1 - 1.8e-18 66.9 0.8 2.4e-10 40.3 0.4 3.2 2 1 1 3 3 3 3 Bacterial capsule synthesis protein PGA_cap HEAT_2 PF13646.6 RLN15341.1 - 0.00019 21.8 0.4 0.24 11.8 0.0 4.3 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.22 RLN15341.1 - 0.0027 17.8 0.2 1.1 9.7 0.0 4.4 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.7 RLN15341.1 - 0.006 16.6 0.4 0.98 9.4 0.0 4.2 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Aminotran_3 PF00202.21 RLN15349.1 - 7.8e-07 28.1 0.0 9.2e-07 27.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Ribosomal_60s PF00428.19 RLN15350.1 - 4.8 7.8 12.4 0.21 12.2 5.0 2.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein Trypan_PARP PF05887.11 RLN15351.1 - 0.00038 20.4 17.8 0.00066 19.7 17.8 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF92 PF01940.16 RLN15351.1 - 5 6.5 6.0 2.1 7.7 0.0 2.1 2 0 0 2 2 2 0 Integral membrane protein DUF92 LMBR1 PF04791.16 RLN15351.1 - 5.5 5.8 12.1 8.1 5.2 12.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein HTH_ABP1_N PF18107.1 RLN15352.1 - 2.8e-08 33.3 0.5 4e-08 32.8 0.5 1.2 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_32 PF13565.6 RLN15352.1 - 0.0022 18.6 1.8 0.0038 17.8 1.8 1.4 1 0 0 1 1 1 1 Homeodomain-like domain FAE1_CUT1_RppA PF08392.12 RLN15352.1 - 0.17 11.1 0.0 0.18 11.1 0.0 1.0 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein Elicitin PF00964.17 RLN15354.1 - 1.5e-23 82.7 0.1 2.2e-23 82.1 0.1 1.2 1 0 0 1 1 1 1 Elicitin Pneumo_att_G PF05539.11 RLN15354.1 - 0.79 9.2 7.2 0.95 9.0 7.2 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G PI-PLC-X PF00388.19 RLN15355.1 - 0.013 15.0 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-C1 PF16670.5 RLN15355.1 - 0.16 11.0 0.3 1.2 8.2 0.3 2.1 1 1 0 1 1 1 0 Phosphoinositide phospholipase C, Ca2+-dependent PLATZ PF04640.14 RLN15357.1 - 0.0079 16.8 0.6 0.011 16.3 0.6 1.5 1 1 0 1 1 1 1 PLATZ transcription factor YacG PF03884.14 RLN15357.1 - 0.082 12.7 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG zf-FLZ PF04570.14 RLN15357.1 - 0.17 11.4 2.4 0.48 9.9 2.4 1.8 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 zf-RING_2 PF13639.6 RLN15358.1 - 2.3e-08 34.2 1.7 2.3e-08 34.2 1.7 4.1 3 2 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN15358.1 - 3.9e-07 29.8 1.7 3.9e-07 29.8 1.7 4.6 4 2 1 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN15358.1 - 1.1e-05 25.2 1.2 1.1e-05 25.2 1.2 5.0 3 2 0 3 3 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RLN15358.1 - 1.1e-05 25.1 1.0 1.1e-05 25.1 1.0 3.9 3 2 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN15358.1 - 0.00017 21.4 1.0 0.00017 21.4 1.0 4.7 3 2 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 RLN15358.1 - 0.00044 19.7 0.2 0.00044 19.7 0.2 1.9 2 1 0 2 2 1 1 Rtf2 RING-finger Zn_ribbon_17 PF17120.5 RLN15358.1 - 0.0015 18.1 0.9 0.0015 18.1 0.9 4.1 3 2 1 4 4 3 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 RLN15358.1 - 0.0017 18.2 0.7 0.0017 18.2 0.7 3.9 3 2 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 RLN15358.1 - 0.0018 18.0 0.5 0.0018 18.0 0.5 4.0 3 2 0 3 3 2 1 RING/Ubox like zinc-binding domain FYDLN_acid PF09538.10 RLN15358.1 - 0.0046 17.6 10.3 0.013 16.1 10.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) zf-RING_UBOX PF13445.6 RLN15358.1 - 0.0059 16.6 2.3 0.0059 16.6 2.3 3.5 3 2 0 3 3 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 RLN15358.1 - 0.048 13.4 0.3 0.048 13.4 0.3 4.2 3 1 1 4 4 4 0 RING-like zinc finger Paf1 PF03985.13 RLN15358.1 - 0.44 9.5 6.2 0.58 9.1 6.2 1.1 1 0 0 1 1 1 0 Paf1 Pellino PF04710.14 RLN15358.1 - 0.7 8.5 4.1 1.1 7.8 4.1 1.3 1 0 0 1 1 1 0 Pellino CDC45 PF02724.14 RLN15358.1 - 1.3 7.2 7.7 1.7 6.8 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RLN15358.1 - 3 6.0 12.8 3.9 5.6 12.8 1.1 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 RLN15360.1 - 6.9e-44 150.2 0.0 1.5e-43 149.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN15360.1 - 1.6e-11 44.0 0.0 4.6e-11 42.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN15360.1 - 0.00079 19.4 0.6 0.0053 16.7 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN15360.1 - 0.022 14.1 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RLN15360.1 - 0.053 13.1 0.2 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.22 RLN15360.1 - 0.082 12.5 0.1 0.43 10.1 0.0 2.1 2 0 0 2 2 2 0 RIO1 family MCM6_C PF18263.1 RLN15360.1 - 4.9 7.4 7.2 0.84 9.9 2.2 2.3 2 0 0 2 2 2 0 MCM6 C-terminal winged-helix domain CH_2 PF06294.11 RLN15361.1 - 2.2e-16 59.8 0.0 6.6e-16 58.2 0.0 1.9 1 0 0 1 1 1 1 CH-like domain in sperm protein CH PF00307.31 RLN15361.1 - 0.0016 18.6 0.0 0.0037 17.4 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain TPT PF03151.16 RLN15362.1 - 7.8e-38 130.5 26.9 9.7e-38 130.2 26.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 RLN15362.1 - 1.8e-09 37.9 30.2 6e-06 26.5 11.5 2.3 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 RLN15362.1 - 1.4e-05 24.5 23.1 2.1e-05 23.9 23.1 1.3 1 0 0 1 1 1 1 UAA transporter family Sugar_tr PF00083.24 RLN15364.1 - 1.2e-29 103.5 4.6 1.2e-29 103.5 4.6 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN15364.1 - 3.9e-24 85.2 17.1 6e-24 84.6 17.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF5555 PF17710.1 RLN15364.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5555) MFS_4 PF06779.14 RLN15364.1 - 0.0046 16.3 11.1 0.0082 15.5 11.1 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB adh_short PF00106.25 RLN15365.1 - 8.4e-32 110.2 0.3 1.6e-30 106.0 0.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN15365.1 - 1.6e-19 70.4 0.1 2.3e-18 66.6 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN15365.1 - 1.3e-09 38.2 0.1 2e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN15365.1 - 9.1e-06 25.3 0.1 1.2e-05 24.9 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 RLN15365.1 - 0.0012 18.2 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Tetraspanin PF00335.20 RLN15366.1 - 1.2e-11 44.8 3.0 1.2e-11 44.7 3.0 1.1 1 0 0 1 1 1 1 Tetraspanin family Thioredoxin_16 PF18569.1 RLN15366.1 - 0.08 13.1 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Cytochrome-c551 PF10643.9 RLN15366.1 - 0.17 11.4 1.9 0.25 10.9 1.9 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Pkinase PF00069.25 RLN15367.1 - 7.5e-47 159.9 0.0 1.1e-43 149.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN15367.1 - 3.8e-30 105.0 0.0 1.1e-28 100.2 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN15367.1 - 4e-06 25.9 0.0 9.1e-06 24.7 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase zf-B_box PF00643.24 RLN15367.1 - 0.00011 22.3 6.5 0.00011 22.3 6.5 1.8 2 0 0 2 2 2 1 B-box zinc finger SAM_1 PF00536.30 RLN15367.1 - 0.0074 16.7 0.1 0.015 15.7 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CEBP_ZZ PF16366.5 RLN15367.1 - 0.015 15.5 4.2 0.034 14.4 4.2 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain SAM_2 PF07647.17 RLN15367.1 - 0.063 13.4 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Seadorna_VP7 PF07387.11 RLN15367.1 - 0.097 11.7 0.2 0.15 11.1 0.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 zf-AN1 PF01428.16 RLN15367.1 - 0.56 10.4 6.2 1.6 9.0 6.2 1.8 1 0 0 1 1 1 0 AN1-like Zinc finger PhoD PF09423.10 RLN15368.1 - 8.9e-17 61.1 0.9 8.4e-16 57.9 0.9 2.3 1 1 0 1 1 1 1 PhoD-like phosphatase cobW PF02492.19 RLN15369.1 - 3e-40 137.7 0.0 4.3e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 RLN15369.1 - 3.1e-18 65.5 0.1 6.2e-18 64.5 0.1 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 RLN15369.1 - 6.8e-05 22.8 0.1 0.26 11.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 RLN15369.1 - 0.00066 20.1 0.1 0.0022 18.4 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.27 RLN15369.1 - 0.0041 16.7 0.1 0.54 9.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain TsaE PF02367.17 RLN15369.1 - 0.0064 16.5 0.1 0.014 15.4 0.1 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE CbtA PF09490.10 RLN15369.1 - 0.0086 15.9 0.5 0.017 14.9 0.5 1.4 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) AAA_22 PF13401.6 RLN15369.1 - 0.014 15.7 0.1 0.071 13.4 0.2 2.2 2 1 0 2 2 2 0 AAA domain LapA_dom PF06305.11 RLN15369.1 - 0.03 14.1 1.3 0.067 13.0 1.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain AAA_5 PF07728.14 RLN15369.1 - 0.072 13.1 0.1 9.4 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1_Xtn PF16897.5 RLN15369.1 - 0.093 12.8 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 RLN15369.1 - 0.11 12.5 0.1 0.86 9.7 0.1 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase TMEM100 PF16311.5 RLN15369.1 - 0.18 11.4 0.5 0.32 10.6 0.5 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 zf-RING_2 PF13639.6 RLN15370.1 - 5.7e-11 42.6 5.4 9.8e-11 41.8 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 RLN15370.1 - 1.3e-07 31.2 3.8 2.6e-07 30.3 3.8 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RLN15370.1 - 3.2e-07 30.1 6.1 6.1e-07 29.2 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN15370.1 - 3.4e-07 30.4 4.9 6.6e-07 29.5 4.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RLN15370.1 - 7.6e-06 25.8 5.8 1.3e-05 25.1 5.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RLN15370.1 - 1.1e-05 25.3 0.6 0.00011 22.2 1.1 2.2 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 RLN15370.1 - 7.8e-05 22.4 7.2 0.00014 21.6 7.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 RLN15370.1 - 0.0001 22.1 4.9 0.00018 21.3 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN15370.1 - 0.00019 21.2 7.2 0.00031 20.5 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 RLN15370.1 - 0.00032 20.3 6.3 0.00055 19.5 6.3 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 RLN15370.1 - 0.015 15.3 4.8 0.033 14.2 4.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 RLN15370.1 - 0.071 13.3 5.0 0.18 12.0 5.0 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 RLN15370.1 - 0.4 10.5 9.3 0.73 9.7 9.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 RLN15370.1 - 0.8 9.9 5.6 1.6 8.9 5.6 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF2160 PF09928.9 RLN15370.1 - 1.1 9.7 4.9 0.3 11.4 0.9 2.2 2 1 0 2 2 1 0 Predicted small integral membrane protein (DUF2160) RINGv PF12906.7 RLN15370.1 - 1.8 8.8 8.2 3.5 7.8 8.2 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 RLN15370.1 - 1.9 8.6 7.0 0.34 11.0 2.9 1.9 2 0 0 2 2 2 0 Zinc-finger CUE PF02845.16 RLN15371.1 - 4.5e-12 45.4 1.8 1.4e-05 24.7 0.1 4.0 4 0 0 4 4 4 3 CUE domain Smr PF01713.21 RLN15371.1 - 1.2e-06 28.8 0.2 3.7e-06 27.2 0.2 1.8 1 0 0 1 1 1 1 Smr domain UBA PF00627.31 RLN15371.1 - 0.0066 16.3 1.5 1.4 8.9 0.1 3.3 3 0 0 3 3 3 2 UBA/TS-N domain DMA PF03474.14 RLN15371.1 - 0.11 12.1 0.0 0.33 10.6 0.0 1.8 1 0 0 1 1 1 0 DMRTA motif HOIP-UBA PF16678.5 RLN15371.1 - 2 8.4 5.0 2.8 8.0 0.0 3.4 4 1 0 4 4 4 0 HOIP UBA domain pair PH PF00169.29 RLN15372.1 - 5.3e-18 65.5 0.0 1.5e-07 31.9 0.0 2.6 2 1 0 2 2 2 2 PH domain PH_11 PF15413.6 RLN15372.1 - 1.5e-10 41.4 0.2 5e-05 23.7 0.0 2.6 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 RLN15372.1 - 0.00048 20.4 1.0 9.4 6.6 0.5 3.9 3 1 0 3 3 3 2 Pleckstrin homology domain PH_6 PF15406.6 RLN15372.1 - 0.0027 18.0 0.0 0.0058 16.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain HAGH_C PF16123.5 RLN15373.1 - 1.1e-26 93.1 0.0 1.9e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 RLN15373.1 - 4.4e-10 39.9 5.8 4.5e-09 36.6 5.7 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 RLN15373.1 - 0.0052 16.3 0.7 0.015 14.9 0.7 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF4841 PF16129.5 RLN15374.1 - 0.024 14.9 6.5 4.3 7.6 0.1 5.3 5 0 0 5 5 5 0 Domain of unknown function (DUF4841) Ral PF11058.8 RLN15374.1 - 0.067 12.8 0.0 19 4.9 0.0 3.6 3 0 0 3 3 3 0 Antirestriction protein Ral CutA1 PF03091.15 RLN15375.1 - 0.012 15.4 0.0 0.03 14.2 0.0 1.8 1 1 0 1 1 1 0 CutA1 divalent ion tolerance protein PmrD PF11183.8 RLN15375.1 - 0.075 13.2 0.0 0.28 11.3 0.0 1.9 1 1 1 2 2 2 0 Polymyxin resistance protein PmrD ATP-synt_J PF04911.12 RLN15375.1 - 0.17 11.5 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 ATP synthase j chain MULE PF10551.9 RLN15377.1 - 5.1e-09 36.4 0.0 9.7e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain Actin PF00022.19 RLN15378.1 - 3.4e-139 464.0 0.0 1.1e-138 462.2 0.0 1.7 1 1 0 1 1 1 1 Actin RNB PF00773.19 RLN20074.1 - 1.6e-91 307.0 0.0 1.6e-91 307.0 0.0 2.0 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 RLN20074.1 - 7.6e-16 57.9 0.0 2e-15 56.6 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 RLN20074.1 - 7.3e-10 39.0 0.0 3.7e-09 36.8 0.0 2.3 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal Rrp44_CSD1 PF17216.3 RLN20074.1 - 3.6e-09 36.5 1.5 5.3e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Rrp44-like cold shock domain CSD2 PF17876.1 RLN20074.1 - 0.006 16.7 0.0 0.067 13.4 0.0 2.7 3 0 0 3 3 3 1 Cold shock domain Macoilin PF09726.9 RLN20074.1 - 0.83 8.1 17.3 1.6 7.2 17.3 1.5 1 0 0 1 1 1 0 Macoilin family DUF4434 PF14488.6 RLN20075.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Glyco_hydro_17 PF00332.18 RLN20076.1 - 7.9e-05 22.4 0.6 0.00085 19.0 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.13 RLN20076.1 - 0.061 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 Unstab_antitox PF09720.10 RLN20076.1 - 0.21 11.7 0.1 0.81 9.8 0.0 1.9 2 0 0 2 2 2 0 Putative addiction module component bZIP_C PF12498.8 RLN20076.1 - 0.37 11.8 1.3 5.5 8.0 0.2 2.2 2 0 0 2 2 2 0 Basic leucine-zipper C terminal PEP_mutase PF13714.6 RLN20085.1 - 3.6e-47 160.8 0.6 4.5e-47 160.5 0.6 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 RLN20085.1 - 1e-12 47.4 0.2 1.4e-12 46.9 0.2 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 RLN20085.1 - 2.2e-05 24.0 0.3 0.00029 20.3 0.0 2.1 1 1 1 2 2 2 1 Ketopantoate hydroxymethyltransferase PEP_hydrolase PF09370.10 RLN20085.1 - 0.032 13.5 0.9 0.13 11.5 0.2 2.0 1 1 1 2 2 2 0 Phosphoenolpyruvate hydrolase-like TUDOR_5 PF18359.1 RLN20088.1 - 1.2e-05 24.9 0.3 2.7e-05 23.8 0.2 1.6 2 0 0 2 2 2 1 Histone methyltransferase Tudor domain 1 Agenet PF05641.12 RLN20088.1 - 0.0021 18.5 0.5 0.0043 17.5 0.5 1.6 1 0 0 1 1 1 1 Agenet domain LBR_tudor PF09465.10 RLN20088.1 - 0.013 15.3 0.1 0.023 14.5 0.1 1.3 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain DUF1325 PF07039.11 RLN20088.1 - 0.045 13.9 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 SGF29 tudor-like domain Ank_2 PF12796.7 RLN20088.1 - 0.15 12.7 0.1 0.54 10.9 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) START PF01852.19 RLN20089.1 - 3.7e-07 29.8 0.2 8.9e-07 28.5 0.2 1.6 1 1 0 1 1 1 1 START domain DNA_pol3_a_NI PF14480.6 RLN20089.1 - 0.14 12.2 0.1 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I ERAP1_C PF11838.8 RLN20090.1 - 1.9e-69 234.7 0.4 3.1e-69 234.0 0.4 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 RLN20090.1 - 2.4e-41 141.7 2.2 4.1e-41 140.9 2.2 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ELFV_dehydrog PF00208.21 RLN20091.1 - 7.1e-35 120.9 0.0 1.3e-34 120.1 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 RLN20091.1 - 2.2e-22 78.6 3.2 1.2e-19 69.4 0.4 3.3 2 2 1 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 RLN20091.1 - 0.031 14.2 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain MORN PF02493.20 RLN20092.1 - 0.013 15.3 1.3 14 5.8 0.0 3.5 3 0 0 3 3 3 0 MORN repeat Takusan PF04822.13 RLN20092.1 - 0.079 12.9 0.2 0.19 11.6 0.2 1.6 1 0 0 1 1 1 0 Takusan DUF4559 PF15112.6 RLN20092.1 - 2.3 7.8 9.3 3.4 7.2 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) FYVE_2 PF02318.16 RLN20093.1 - 0.082 13.1 14.5 0.6 10.3 14.6 2.3 1 1 1 2 2 2 0 FYVE-type zinc finger FYVE PF01363.21 RLN20093.1 - 0.087 13.0 18.9 0.082 13.1 17.3 1.8 2 0 0 2 2 2 0 FYVE zinc finger Siva PF05458.12 RLN20093.1 - 4.2 7.0 15.2 4.6 6.9 13.9 1.7 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Lipoxygenase PF00305.19 RLN20094.1 - 2.1e-17 62.9 0.3 1.1e-16 60.5 0.3 2.0 1 1 0 1 1 1 1 Lipoxygenase FYVE PF01363.21 RLN20095.1 - 3.8e-06 27.0 13.2 3.8e-06 27.0 13.2 2.1 1 1 1 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 RLN20095.1 - 0.0035 17.6 11.7 0.01 16.1 11.7 1.9 1 1 0 1 1 1 1 FYVE-type zinc finger DUF4483 PF14825.6 RLN20095.1 - 0.088 12.6 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) Syja_N PF02383.18 RLN20096.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 SacI homology domain FYVE PF01363.21 RLN20097.1 - 0.00015 21.9 10.3 0.00045 20.3 10.3 1.8 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN20097.1 - 0.00019 21.6 6.6 0.00037 20.7 6.6 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger Spore_SspJ PF09575.10 RLN20097.1 - 0.027 14.8 0.0 10 6.6 0.0 2.6 2 0 0 2 2 2 0 Small spore protein J (Spore_SspJ) C1_2 PF03107.16 RLN20097.1 - 0.14 12.5 3.2 0.4 11.0 3.2 1.8 1 0 0 1 1 1 0 C1 domain zf-UDP PF14569.6 RLN20097.1 - 0.54 10.4 2.8 1.2 9.3 2.8 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-B_box PF00643.24 RLN20097.1 - 0.88 9.8 9.6 0.11 12.7 5.1 1.9 2 0 0 2 2 2 0 B-box zinc finger RCC1 PF00415.18 RLN20098.1 - 8.9e-60 199.1 27.6 1.2e-12 48.2 0.3 8.0 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN20098.1 - 6.5e-38 127.8 43.2 8.3e-10 38.2 1.2 9.2 9 0 0 9 9 9 7 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 RLN20098.1 - 1.7e-20 73.3 0.1 8.3e-12 45.3 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain AAA_19 PF13245.6 RLN20098.1 - 0.16 12.3 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Fe_hyd_SSU PF02256.17 RLN20099.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Iron hydrogenase small subunit p450 PF00067.22 RLN20100.1 - 1.3e-73 248.4 0.0 1.7e-73 247.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Kelch_4 PF13418.6 RLN20101.1 - 5.9e-26 90.2 4.6 0.00013 21.9 0.1 6.2 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 RLN20101.1 - 1.9e-21 75.8 4.5 0.00048 20.3 0.0 6.9 6 1 0 6 6 6 5 Galactose oxidase, central domain DUF4110 PF13422.6 RLN20101.1 - 8.3e-19 67.5 0.0 8.3e-19 67.5 0.0 4.6 4 1 1 5 5 5 1 Domain of unknown function (DUF4110) Kelch_5 PF13854.6 RLN20101.1 - 1.3e-18 66.6 1.1 0.0043 17.0 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 RLN20101.1 - 3.4e-11 43.0 0.4 0.076 13.3 0.0 5.0 3 2 1 4 4 4 4 Kelch motif Kelch_2 PF07646.15 RLN20101.1 - 7.1e-09 35.3 1.0 0.0064 16.4 0.0 5.1 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.25 RLN20101.1 - 1e-08 34.6 1.6 0.0099 15.4 0.0 4.9 5 0 0 5 5 5 2 Kelch motif DUF2207 PF09972.9 RLN20101.1 - 1.5 7.5 4.6 3.1 6.5 4.6 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Bin3 PF06859.12 RLN20102.1 - 3.2e-38 130.7 0.0 6e-38 129.8 0.0 1.4 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_12 PF08242.12 RLN20102.1 - 9.3e-06 26.3 0.0 0.0037 18.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 RLN20102.1 - 0.00023 21.0 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 RLN20102.1 - 0.00061 20.4 0.0 0.33 11.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 RLN20102.1 - 0.0014 18.5 0.0 0.0037 17.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN20102.1 - 0.0064 17.1 0.0 0.33 11.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ribosomal_S9 PF00380.19 RLN20103.1 - 9.5e-23 81.0 0.3 1.1e-22 80.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF2102 PF09875.9 RLN20103.1 - 0.043 13.5 0.2 0.056 13.2 0.2 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) LSM PF01423.22 RLN20104.1 - 1.8e-14 53.2 0.6 2.4e-14 52.8 0.6 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RLN20104.1 - 3.4e-05 23.9 0.0 4.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain tRNA_anti_2 PF13742.6 RLN20104.1 - 0.18 12.0 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain ABC_tran PF00005.27 RLN20121.1 - 6.1e-18 65.7 0.0 1e-17 64.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter DDE_3 PF13358.6 RLN20121.1 - 3.3e-11 43.1 0.0 5.7e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Zeta_toxin PF06414.12 RLN20121.1 - 0.0013 18.0 0.0 0.007 15.7 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 RLN20121.1 - 0.0031 17.9 0.1 0.012 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain DUF1563 PF07599.11 RLN20121.1 - 0.0072 16.4 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1563) AAA_29 PF13555.6 RLN20121.1 - 0.01 15.6 0.6 0.029 14.1 0.6 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 RLN20121.1 - 0.019 15.0 0.0 0.1 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 RLN20121.1 - 0.031 14.2 0.1 0.057 13.3 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase G-alpha PF00503.20 RLN20121.1 - 0.037 13.2 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit DUF815 PF05673.13 RLN20121.1 - 0.042 13.0 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RuvC PF02075.17 RLN20121.1 - 0.051 13.4 0.1 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 Crossover junction endodeoxyribonuclease RuvC AAA_22 PF13401.6 RLN20121.1 - 0.06 13.6 0.0 0.18 12.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 RLN20121.1 - 0.062 13.8 0.0 0.44 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 RLN20121.1 - 0.065 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 MMR_HSR1 PF01926.23 RLN20121.1 - 0.093 12.8 0.1 0.3 11.2 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase VirE PF05272.11 RLN20121.1 - 0.15 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E UFD1 PF03152.14 RLN20130.1 - 2.6e-64 215.8 0.0 4.5e-64 215.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Cytochrom_B_C PF00032.17 RLN20131.1 - 0.011 16.0 0.1 0.014 15.7 0.1 1.2 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD HTH_Tnp_Tc5 PF03221.16 RLN20132.1 - 0.0034 17.4 0.0 0.0063 16.5 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain KIX_2 PF16987.5 RLN20132.1 - 0.018 15.0 0.1 0.14 12.2 0.1 2.3 2 1 0 2 2 2 0 KIX domain MEDS PF14417.6 RLN20132.1 - 0.03 14.2 0.1 0.27 11.1 0.0 2.4 1 1 2 3 3 3 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain mRNA_triPase PF02940.15 RLN20132.1 - 0.07 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme, beta chain adh_short PF00106.25 RLN20133.1 - 4.6e-35 120.9 2.0 5.5e-19 68.4 0.0 3.0 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN20133.1 - 2.3e-32 112.4 3.9 3.3e-26 92.3 0.2 2.7 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.19 RLN20133.1 - 0.0065 15.8 0.3 0.016 14.5 0.0 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KR PF08659.10 RLN20133.1 - 0.015 15.2 0.1 0.033 14.1 0.1 1.6 1 0 0 1 1 1 0 KR domain Shikimate_DH PF01488.20 RLN20133.1 - 0.087 12.9 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pkinase PF00069.25 RLN20134.1 - 1.1e-52 179.1 0.0 1.6e-52 178.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN20134.1 - 2.6e-25 89.2 0.0 3.9e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN20134.1 - 5.3e-05 22.2 0.0 9.2e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 RLN20134.1 - 0.096 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SIR2 PF02146.17 RLN20135.1 - 0.038 13.9 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 Sir2 family Tautomerase_2 PF14552.6 RLN20135.1 - 0.056 13.5 0.0 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 Tautomerase enzyme LRR_6 PF13516.6 RLN20136.1 - 7.2e-19 66.2 12.7 1.5e-05 24.6 0.2 5.1 6 0 0 6 6 6 4 Leucine Rich repeat Atx10homo_assoc PF09759.9 RLN20136.1 - 0.00025 21.0 0.4 0.00079 19.4 0.0 1.9 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain LRR_4 PF12799.7 RLN20136.1 - 0.0011 19.3 0.6 0.51 10.8 0.1 3.2 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN20136.1 - 0.0016 18.1 1.9 0.02 14.6 0.1 3.0 2 1 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 RLN20136.1 - 0.011 16.2 0.1 8.4 7.4 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich Repeat DNA_pol_phi PF04931.13 RLN20136.1 - 0.93 7.5 11.3 1.6 6.7 11.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi LisH_2 PF16045.5 RLN20137.1 - 1.3e-08 33.7 0.0 2.4e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 LisH FOP_dimer PF09398.10 RLN20137.1 - 0.028 14.7 0.0 0.11 12.8 0.0 2.1 1 1 0 1 1 1 0 FOP N terminal dimerisation domain DUF2621 PF11084.8 RLN20158.1 - 0.41 10.6 2.9 0.59 10.1 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2621) Pkinase PF00069.25 RLN20159.1 - 2.2e-35 122.3 0.0 2e-18 66.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN20159.1 - 5.2e-19 68.5 0.0 1.4e-18 67.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase CDC45 PF02724.14 RLN20159.1 - 0.0083 14.5 0.7 0.0089 14.4 0.7 1.1 1 0 0 1 1 1 1 CDC45-like protein TFIIF_alpha PF05793.12 RLN20159.1 - 0.77 8.3 8.0 1.1 7.8 8.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pkinase PF00069.25 RLN20160.1 - 4.8e-47 160.5 0.0 7.1e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN20160.1 - 2e-46 158.4 0.0 2.7e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 RLN20160.1 - 1.8e-09 37.7 1.7 8.1e-05 22.9 0.3 4.3 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN20160.1 - 4.9e-09 35.8 3.1 0.00016 21.4 0.3 2.8 2 1 1 3 3 3 2 Leucine rich repeat DUF1180 PF06679.12 RLN20160.1 - 6.6e-05 23.4 1.5 0.00014 22.3 1.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) TMEM154 PF15102.6 RLN20160.1 - 0.0046 16.9 0.1 0.009 15.9 0.1 1.5 1 0 0 1 1 1 1 TMEM154 protein family FNIP PF05725.12 RLN20160.1 - 0.0057 16.8 0.5 0.12 12.6 0.5 2.6 1 1 0 1 1 1 1 FNIP Repeat APH PF01636.23 RLN20160.1 - 0.034 14.1 0.1 0.059 13.3 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN20160.1 - 0.044 12.6 0.0 0.044 12.6 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase TNFR_16_TM PF18422.1 RLN20160.1 - 0.056 13.4 1.5 0.11 12.5 1.5 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF202 PF02656.15 RLN20160.1 - 0.057 13.9 0.5 0.21 12.0 0.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF202) SKG6 PF08693.10 RLN20160.1 - 0.069 12.6 2.0 0.17 11.3 2.0 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LRR_9 PF14580.6 RLN20160.1 - 0.13 11.7 0.0 0.45 10.0 0.0 1.9 2 0 0 2 2 2 0 Leucine-rich repeat EphA2_TM PF14575.6 RLN20160.1 - 0.14 13.1 0.0 0.35 11.8 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PMP1_2 PF08114.11 RLN20160.1 - 0.14 11.9 0.6 0.39 10.5 0.6 1.7 1 0 0 1 1 1 0 ATPase proteolipid family Pkinase PF00069.25 RLN20161.1 - 1.2e-98 329.7 0.0 1.3e-49 168.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN20161.1 - 9.4e-92 306.9 0.0 5.5e-46 156.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN20161.1 - 3.6e-07 29.3 0.0 0.022 13.6 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase LRR_8 PF13855.6 RLN20161.1 - 4.5e-07 29.5 5.0 0.0053 16.5 2.3 3.1 3 0 0 3 3 3 2 Leucine rich repeat APH PF01636.23 RLN20161.1 - 3.5e-05 23.8 0.5 3.4 7.5 0.0 3.6 2 1 0 3 3 3 2 Phosphotransferase enzyme family LRR_4 PF12799.7 RLN20161.1 - 0.00014 22.2 11.8 0.046 14.2 2.5 5.0 3 1 4 7 7 7 2 Leucine Rich repeats (2 copies) Haspin_kinase PF12330.8 RLN20161.1 - 0.0017 17.3 0.0 2.2 7.2 0.0 2.6 3 0 0 3 3 3 2 Haspin like kinase domain DUF4381 PF14316.6 RLN20161.1 - 0.002 18.4 0.0 0.11 12.7 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) LapA_dom PF06305.11 RLN20161.1 - 0.0071 16.1 5.0 0.26 11.2 0.5 3.0 3 0 0 3 3 3 1 Lipopolysaccharide assembly protein A domain DUF4755 PF15947.5 RLN20161.1 - 0.0082 16.1 0.0 6.4 6.8 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4755) Kdo PF06293.14 RLN20161.1 - 0.016 14.5 0.0 6.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family TMEM154 PF15102.6 RLN20161.1 - 0.017 15.0 0.0 0.35 10.8 0.0 3.0 3 1 1 4 4 3 0 TMEM154 protein family Herpes_gE PF02480.16 RLN20161.1 - 0.041 12.6 0.0 1 8.1 0.0 2.2 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Pox_ser-thr_kin PF05445.11 RLN20161.1 - 0.082 11.9 0.1 11 4.8 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase DUF2561 PF10812.8 RLN20161.1 - 0.35 10.9 2.4 17 5.4 1.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2561) Nuc_sug_transp PF04142.15 RLN20162.1 - 1.7e-31 109.6 15.9 2.1e-31 109.3 15.9 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 RLN20162.1 - 1.1e-05 25.6 26.0 0.011 16.0 2.3 2.4 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 RLN20162.1 - 0.00021 20.6 18.0 0.00049 19.4 18.0 1.6 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 RLN20162.1 - 0.00051 19.4 20.0 0.0024 17.1 20.1 1.8 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport TPT PF03151.16 RLN20162.1 - 0.14 11.5 11.6 0.33 10.3 9.3 2.6 1 1 1 2 2 2 0 Triose-phosphate Transporter family DUF983 PF06170.12 RLN20162.1 - 1.1 9.6 0.0 1.1 9.6 0.0 3.3 4 1 0 4 4 4 0 Protein of unknown function (DUF983) SM-ATX PF14438.6 RLN20163.1 - 1.7e-13 50.5 0.0 2.7e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain LsmAD PF06741.13 RLN20163.1 - 1.3e-06 28.8 0.2 2.7e-06 27.8 0.2 1.6 1 0 0 1 1 1 1 LsmAD domain LSM14 PF12701.7 RLN20163.1 - 0.0098 16.0 0.0 0.029 14.5 0.0 1.7 2 0 0 2 2 2 1 Scd6-like Sm domain DnaJ PF00226.31 RLN20164.1 - 4.9e-24 84.2 5.3 1e-23 83.2 5.3 1.6 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 RLN20164.1 - 7.5e-10 38.7 0.1 2.8e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Sigma70_ner PF04546.13 RLN20164.1 - 0.0018 18.2 1.7 0.65 9.8 0.0 2.5 3 0 0 3 3 3 2 Sigma-70, non-essential region LprI PF07007.12 RLN20164.1 - 0.17 12.6 1.7 0.76 10.5 0.1 2.3 2 0 0 2 2 2 0 Lysozyme inhibitor LprI BT1 PF03092.16 RLN20166.1 - 2.2e-17 62.5 10.4 4.7e-13 48.2 0.4 3.3 3 0 0 3 3 3 3 BT1 family Glucan_synthase PF02364.15 RLN20167.1 - 7e-21 74.1 0.2 1.4e-20 73.2 0.2 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component Sugar_tr PF00083.24 RLN20167.1 - 3.3e-17 62.5 24.6 3.3e-17 62.5 24.6 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter FAM176 PF14851.6 RLN20167.1 - 0.077 12.7 0.0 0.077 12.7 0.0 3.1 3 0 0 3 3 3 0 FAM176 family HAT_KAT11 PF08214.11 RLN20168.1 - 5.5e-24 85.1 16.6 5.2e-23 81.9 0.0 3.5 2 1 1 3 3 3 2 Histone acetylation protein zf-TAZ PF02135.16 RLN20168.1 - 8.8e-24 83.8 65.1 4.5e-11 43.1 15.5 5.5 6 1 0 6 6 6 3 TAZ zinc finger Bromodomain PF00439.25 RLN20168.1 - 5.9e-19 67.9 0.1 1.6e-18 66.5 0.1 1.8 1 0 0 1 1 1 1 Bromodomain ZZ PF00569.17 RLN20168.1 - 1.8e-07 30.8 5.7 1.8e-07 30.8 5.7 5.9 7 0 0 7 7 7 1 Zinc finger, ZZ type PHD PF00628.29 RLN20168.1 - 9.8e-06 25.4 3.4 9.8e-06 25.4 3.4 5.2 4 1 1 5 5 5 1 PHD-finger DUF902 PF06001.13 RLN20168.1 - 0.0053 17.2 3.6 0.013 16.0 3.6 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF902) GCFC PF07842.12 RLN20170.1 - 2.9e-06 27.1 0.1 8.9e-06 25.5 0.1 1.8 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein Thg1C PF14413.6 RLN20170.1 - 0.025 14.7 0.5 0.06 13.5 0.5 1.6 1 0 0 1 1 1 0 Thg1 C terminal domain GvpG PF05120.12 RLN20170.1 - 0.079 13.0 1.0 5.9 7.0 0.0 2.9 2 0 0 2 2 2 0 Gas vesicle protein G Cupin_8 PF13621.6 RLN20171.1 - 7.1e-17 62.0 0.0 1.2e-16 61.3 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 RLN20171.1 - 0.0046 17.4 0.0 0.0073 16.7 0.0 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 RLN20171.1 - 0.017 14.6 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Glyco_hydro_17 PF00332.18 RLN20172.1 - 8.2e-08 32.2 1.4 2.1e-07 30.9 0.6 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 Pkinase PF00069.25 RLN20173.1 - 1.1e-63 215.1 0.0 1.5e-63 214.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN20173.1 - 5.8e-25 88.1 0.0 9e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN20173.1 - 1.6e-05 24.4 0.4 8.2e-05 22.1 0.2 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN20173.1 - 0.00084 18.7 0.0 0.002 17.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RLN20173.1 - 0.024 13.6 0.1 0.038 12.9 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 RLN20173.1 - 0.13 11.8 0.1 0.4 10.3 0.1 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 NOA36 PF06524.12 RLN20173.1 - 5.6 6.2 7.9 9.5 5.4 7.9 1.3 1 0 0 1 1 1 0 NOA36 protein Oxidored_FMN PF00724.20 RLN20174.1 - 9.8e-85 284.8 0.0 1.1e-84 284.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pkinase PF00069.25 RLN20175.1 - 1.6e-65 221.1 0.2 2.5e-65 220.5 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain PP2C PF00481.21 RLN20175.1 - 3.5e-47 161.2 0.0 1.1e-43 149.7 0.0 2.8 2 0 0 2 2 2 2 Protein phosphatase 2C Pkinase_Tyr PF07714.17 RLN20175.1 - 6.8e-38 130.4 0.2 1.1e-37 129.7 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 RLN20175.1 - 3.7e-37 126.3 0.0 3e-17 62.4 0.0 3.0 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 RLN20175.1 - 2e-06 27.4 0.0 3.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN20175.1 - 0.00055 19.9 0.0 0.8 9.6 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN20175.1 - 0.00083 18.2 1.7 0.0035 16.2 1.7 2.0 1 1 0 1 1 1 1 Fungal protein kinase PX PF00787.24 RLN20176.1 - 7.7e-07 29.1 0.0 1.6e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 PX domain E7R PF17467.2 RLN20176.1 - 0.041 14.1 0.0 0.085 13.0 0.0 1.4 1 0 0 1 1 1 0 Viral Protein E7 AMP-binding PF00501.28 RLN20177.1 - 1.7e-79 267.4 0.0 1.9e-79 267.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN20177.1 - 7.9e-16 58.8 0.0 2e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AhpC-TSA PF00578.21 RLN20178.1 - 7.1e-37 126.1 0.0 9.8e-37 125.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RLN20178.1 - 1.1e-16 60.9 0.0 1.5e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 RLN20178.1 - 1.3e-13 50.5 0.0 2.2e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 RLN20178.1 - 0.08 12.9 0.1 0.28 11.1 0.1 1.8 2 0 0 2 2 2 0 SCO1/SenC PH PF00169.29 RLN20179.1 - 0.00018 22.0 0.1 0.00049 20.6 0.1 1.8 1 0 0 1 1 1 1 PH domain Kelch_1 PF01344.25 RLN20180.1 - 3.7e-40 135.3 4.3 7.1e-09 35.1 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 RLN20180.1 - 1.1e-36 123.9 9.6 1.9e-08 34.3 0.2 5.6 3 2 2 5 5 5 5 Kelch motif Kelch_3 PF13415.6 RLN20180.1 - 2.1e-36 123.5 14.7 2.9e-09 37.0 0.1 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.6 RLN20180.1 - 1.5e-33 114.6 16.1 3.3e-10 39.8 0.2 5.9 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN20180.1 - 2.1e-29 101.0 11.1 3.3e-06 26.9 0.2 5.9 5 1 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 RLN20180.1 - 4.8e-28 96.0 8.4 1.4e-06 28.1 0.2 5.3 5 0 0 5 5 5 5 Kelch motif Tfb2 PF03849.14 RLN20181.1 - 5.5e-104 347.9 0.1 2.5e-84 283.3 0.0 2.0 1 1 1 2 2 2 2 Transcription factor Tfb2 Tfb2_C PF18307.1 RLN20181.1 - 2e-22 79.3 0.2 6e-22 77.8 0.2 1.9 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 RLN20181.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Ank_4 PF13637.6 RLN20185.1 - 1.3e-07 32.0 0.9 2e-05 25.1 0.1 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN20185.1 - 1.1e-05 25.5 4.2 0.0018 18.5 0.5 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN20185.1 - 3e-05 24.5 0.1 0.00014 22.4 0.0 2.1 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 RLN20185.1 - 0.00045 20.6 1.0 1.3 9.6 0.0 3.2 3 2 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 RLN20185.1 - 0.0082 16.6 1.8 0.22 12.2 0.0 3.6 5 0 0 5 5 5 1 Ankyrin repeat SNF2_N PF00176.23 RLN20186.1 - 4.8e-56 190.0 1.2 5.3e-55 186.5 0.2 2.4 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN20186.1 - 1e-10 41.9 0.0 2.4e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN20186.1 - 0.0027 17.7 0.0 0.011 15.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Rootletin PF15035.6 RLN20187.1 - 0.002 18.2 3.3 0.002 18.2 3.3 1.9 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion CENP-F_N PF10481.9 RLN20187.1 - 0.0036 17.0 1.6 0.0036 17.0 1.6 2.2 2 0 0 2 2 2 1 Cenp-F N-terminal domain ZapB PF06005.12 RLN20187.1 - 0.058 13.8 7.8 0.24 11.8 7.8 2.1 1 0 0 1 1 1 0 Cell division protein ZapB Exonuc_VII_L PF02601.15 RLN20187.1 - 0.2 11.2 2.5 0.37 10.3 2.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Rep-A_N PF04057.12 RLN20187.1 - 0.24 11.4 0.7 2 8.5 0.2 2.2 2 0 0 2 2 2 0 Replication factor-A protein 1, N-terminal domain Cyclin_N PF00134.23 RLN20188.1 - 2.6e-23 82.1 0.2 2.6e-23 82.1 0.2 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Xin PF08043.12 RLN20188.1 - 0.14 11.8 0.9 0.3 10.8 0.9 1.5 1 0 0 1 1 1 0 Xin repeat Transket_pyr PF02779.24 RLN20192.1 - 9.4e-57 191.5 0.0 1.6e-56 190.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 RLN20192.1 - 3.5e-48 163.1 0.0 6.4e-48 162.3 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 RLN20192.1 - 2.3e-45 154.9 0.0 3.8e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Erf4 PF10256.9 RLN20192.1 - 0.081 13.0 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Hemopexin PF00045.19 RLN20192.1 - 0.13 12.3 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Hemopexin Vps16_C PF04840.12 RLN20193.1 - 6e-17 61.7 0.0 1.5e-14 53.8 0.0 2.2 1 1 0 2 2 2 2 Vps16, C-terminal region HrpB1_HrpK PF09613.10 RLN20193.1 - 0.029 14.0 0.9 0.86 9.3 0.1 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) Myosin_head PF00063.21 RLN20194.1 - 1.2e-227 757.4 0.0 1.5e-227 757.1 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 RLN20194.1 - 1.6e-18 64.7 22.0 3.1e-06 26.5 0.3 4.9 4 0 0 4 4 4 4 IQ calmodulin-binding motif PDZ_6 PF17820.1 RLN20194.1 - 1.7e-05 24.6 0.0 0.31 10.9 0.0 3.5 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 RLN20194.1 - 0.00034 20.9 0.1 0.011 16.1 0.0 3.0 3 0 0 3 3 3 1 PDZ domain PDZ_2 PF13180.6 RLN20194.1 - 0.0015 18.8 0.0 0.47 10.8 0.0 2.7 2 0 0 2 2 2 1 PDZ domain Sigma54_activat PF00158.26 RLN20194.1 - 0.0015 18.2 0.0 0.0043 16.8 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 RLN20194.1 - 0.017 15.5 0.0 0.29 11.5 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 RLN20194.1 - 0.083 12.2 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 RLN20194.1 - 0.13 12.5 0.0 0.46 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain TRL PF13146.6 RLN20194.1 - 0.18 12.1 0.0 4.1 7.7 0.0 2.5 2 0 0 2 2 2 0 TRL-like protein family zf-MYND PF01753.18 RLN20195.1 - 4.4e-07 29.9 12.8 4.4e-07 29.9 12.8 1.6 2 0 0 2 2 2 1 MYND finger Pico_P2A PF00947.19 RLN20195.1 - 0.041 13.9 1.2 0.073 13.1 1.2 1.3 1 0 0 1 1 1 0 Picornavirus core protein 2A zf-Mss51 PF13824.6 RLN20195.1 - 0.73 10.0 9.2 3.1 8.0 9.3 2.0 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 PH PF00169.29 RLN20196.1 - 3e-09 37.3 0.3 8.2e-09 35.9 0.3 1.7 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN20196.1 - 0.00012 22.4 1.5 0.00054 20.3 0.4 2.1 1 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 RLN20196.1 - 0.013 15.8 0.3 0.025 14.9 0.2 1.5 1 1 0 1 1 1 0 Pleckstrin homology domain Memo PF01875.17 RLN20197.1 - 1.1e-12 47.7 0.6 1.8e-07 30.6 0.0 2.0 1 1 1 2 2 2 2 Memo-like protein Med31 PF05669.12 RLN20198.1 - 4.9e-34 116.2 4.7 3.1e-26 91.2 2.7 2.1 2 0 0 2 2 2 2 SOH1 FTHFS PF01268.19 RLN20199.1 - 7e-222 737.5 0.1 3.8e-221 735.1 0.1 2.0 1 1 0 1 1 1 1 Formate--tetrahydrofolate ligase CbiA PF01656.23 RLN20199.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PepSY PF03413.19 RLN20199.1 - 0.15 12.7 0.0 0.37 11.4 0.0 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Thioredoxin_8 PF13905.6 RLN20201.1 - 1.1e-25 89.8 0.0 1.6e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 RLN20201.1 - 3.5e-08 33.4 0.1 0.00093 19.2 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin Redoxin PF08534.10 RLN20201.1 - 5.4e-08 32.7 0.0 7.8e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 RLN20201.1 - 3.1e-07 30.8 0.0 5.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 RLN20201.1 - 3.9e-07 30.0 0.0 5.5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Keratin_2_head PF16208.5 RLN20201.1 - 0.078 13.1 21.2 0.13 12.3 21.2 1.4 1 0 0 1 1 1 0 Keratin type II head UL11 PF11094.8 RLN20201.1 - 0.08 12.8 0.3 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 Membrane-associated tegument protein DUF2922 PF11148.8 RLN20201.1 - 0.14 11.9 0.0 16 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) Glutaredoxin PF00462.24 RLN20201.1 - 0.19 12.0 0.1 1.8 8.8 0.1 2.3 1 1 0 1 1 1 0 Glutaredoxin Lactamase_B_2 PF12706.7 RLN20202.1 - 1.7e-25 89.7 0.0 5.2e-25 88.1 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 RLN20202.1 - 6.6e-07 29.5 0.2 1.4e-06 28.4 0.2 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily HSP70 PF00012.20 RLN20203.1 - 1e-14 53.7 0.1 1.2e-14 53.5 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein FtsA PF14450.6 RLN20203.1 - 0.12 12.8 0.1 0.16 12.4 0.1 1.2 1 0 0 1 1 1 0 Cell division protein FtsA Dor1 PF04124.12 RLN20204.1 - 8.3e-35 120.1 3.7 7e-31 107.1 3.0 2.4 2 1 0 2 2 2 2 Dor1-like family Vps51 PF08700.11 RLN20204.1 - 3.7e-06 26.9 0.9 3.7e-06 26.9 0.9 2.1 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.6 RLN20204.1 - 0.015 15.1 1.1 0.062 13.1 1.1 1.9 1 1 0 1 1 1 0 Exocyst complex component Sec5 PNK3P PF08645.11 RLN20204.1 - 0.18 11.5 0.1 0.38 10.4 0.1 1.5 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase Lactamase_B_2 PF12706.7 RLN20205.1 - 9.4e-26 90.6 0.0 3.3e-25 88.8 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 RLN20205.1 - 9e-06 25.8 0.1 2.7e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Rubis-subs-bind PF09273.11 RLN20206.1 - 9.4e-17 61.9 8.6 5.3e-12 46.5 0.3 4.9 3 0 0 3 3 3 2 Rubisco LSMT substrate-binding SET PF00856.28 RLN20206.1 - 0.0054 17.1 0.0 0.0054 17.1 0.0 7.0 7 2 0 7 7 7 1 SET domain SET PF00856.28 RLN20207.1 - 5.5e-12 46.4 0.0 4.5e-10 40.2 0.0 2.1 1 1 1 2 2 2 2 SET domain SAF PF08666.12 RLN20207.1 - 0.011 16.3 0.0 0.13 12.9 0.0 2.1 1 1 0 1 1 1 0 SAF domain UQ_con PF00179.26 RLN20208.1 - 9.2e-27 93.4 0.4 1.2e-25 89.8 0.4 2.1 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme EAF PF09816.9 RLN20208.1 - 3e-12 46.8 0.0 9.4e-12 45.2 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor RWD PF05773.22 RLN20208.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain CWC25 PF12542.8 RLN20209.1 - 1.2e-17 64.7 0.2 1.2e-17 64.7 0.2 4.9 3 3 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 RLN20209.1 - 4.3e-09 36.4 10.1 4.3e-09 36.4 10.1 5.9 5 1 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR 2OG-FeII_Oxy PF03171.20 RLN20210.1 - 0.00054 20.4 0.0 0.00078 19.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TMPIT PF07851.13 RLN20211.1 - 3.2 6.9 7.7 4.9 6.3 7.5 1.5 1 1 0 1 1 1 0 TMPIT-like protein TPR_1 PF00515.28 RLN20258.1 - 3.9e-19 67.6 21.1 3.3e-06 26.7 0.1 8.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 RLN20258.1 - 1.9e-16 58.7 23.8 0.00049 20.0 0.1 8.6 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 RLN20258.1 - 1.2e-14 54.6 15.5 1.3e-06 28.8 0.4 5.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN20258.1 - 1.1e-12 47.1 14.9 0.025 14.8 0.2 8.6 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 RLN20258.1 - 2.7e-11 43.0 1.4 1.1e-05 25.0 0.1 4.9 4 0 0 4 4 4 2 TPR repeat Sel1 PF08238.12 RLN20258.1 - 5.3e-11 42.8 6.7 0.0087 16.7 0.0 5.6 6 0 0 6 6 5 3 Sel1 repeat TPR_16 PF13432.6 RLN20258.1 - 1.8e-09 38.1 10.4 8e-06 26.4 0.2 7.2 6 2 3 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 RLN20258.1 - 1.9e-09 37.7 10.9 0.00013 22.2 0.3 6.9 5 1 0 6 6 6 2 Tetratricopeptide repeat zf-MYND PF01753.18 RLN20258.1 - 6.8e-08 32.5 11.0 6.8e-08 32.5 11.0 2.1 2 0 0 2 2 1 1 MYND finger TPR_14 PF13428.6 RLN20258.1 - 2.2e-07 31.1 26.6 0.19 12.6 0.0 9.2 7 2 2 9 9 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN20258.1 - 1.7e-05 24.5 8.1 0.83 9.8 0.0 6.2 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN20258.1 - 3.2e-05 24.1 2.8 1.2 9.4 0.6 5.0 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 RLN20258.1 - 4.1e-05 23.7 3.3 3.3 8.3 0.1 6.6 7 0 0 7 7 6 1 Tetratricopeptide repeat HEPN_Swt1 PF18731.1 RLN20258.1 - 9.6e-05 22.7 0.0 9.6e-05 22.7 0.0 2.2 2 1 1 3 3 1 1 Swt1-like HEPN Fis1_TPR_C PF14853.6 RLN20258.1 - 0.00041 20.4 4.7 0.23 11.6 0.0 4.3 5 0 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat Paf67 PF10255.9 RLN20258.1 - 0.009 15.1 0.5 0.035 13.1 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase I-associated factor PAF67 DUF3856 PF12968.7 RLN20258.1 - 0.025 14.7 4.2 0.2 11.7 0.1 4.0 4 1 0 5 5 4 0 Domain of Unknown Function (DUF3856) MIT PF04212.18 RLN20258.1 - 0.028 14.5 7.2 0.24 11.5 0.1 3.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_9 PF13371.6 RLN20258.1 - 0.077 13.2 6.1 0.19 11.9 0.1 3.9 4 0 0 4 4 2 0 Tetratricopeptide repeat zf-Di19 PF05605.12 RLN20258.1 - 0.27 11.5 5.4 0.72 10.2 5.4 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding adh_short PF00106.25 RLN20260.1 - 6.9e-37 126.8 0.7 9.1e-37 126.4 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN20260.1 - 3.2e-24 85.8 0.5 3.9e-24 85.5 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN20260.1 - 1.5e-05 25.0 0.6 2.3e-05 24.4 0.3 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN20260.1 - 0.0022 17.5 0.1 0.0027 17.2 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 RLN20260.1 - 0.018 14.9 0.7 0.03 14.2 0.7 1.4 1 1 0 1 1 1 0 NAD(P)H-binding Ank_4 PF13637.6 RLN20261.1 - 0.058 14.0 0.2 0.18 12.4 0.2 1.8 1 1 0 1 1 1 0 Ankyrin repeats (many copies) adh_short PF00106.25 RLN20262.1 - 4.2e-71 238.5 10.0 2.7e-36 124.9 1.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN20262.1 - 1.3e-48 165.6 8.0 3.6e-26 92.1 0.4 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 RLN20262.1 - 7.4e-12 45.2 1.0 0.0001 21.9 0.1 2.7 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family KR PF08659.10 RLN20262.1 - 5.5e-10 39.4 2.3 0.00014 21.8 0.1 2.6 2 1 0 2 2 2 2 KR domain NAD_binding_10 PF13460.6 RLN20262.1 - 5.5e-08 32.9 4.6 0.00019 21.4 0.3 2.5 2 0 0 2 2 2 2 NAD(P)H-binding RmlD_sub_bind PF04321.17 RLN20262.1 - 1.8e-05 24.0 0.3 0.12 11.5 0.1 2.4 2 0 0 2 2 2 2 RmlD substrate binding domain NmrA PF05368.13 RLN20262.1 - 9.6e-05 22.0 1.9 0.11 12.1 0.2 2.7 3 0 0 3 3 3 2 NmrA-like family FtsJ PF01728.19 RLN20262.1 - 0.002 18.3 0.0 0.86 9.7 0.0 2.5 2 0 0 2 2 2 2 FtsJ-like methyltransferase Eno-Rase_NADH_b PF12242.8 RLN20262.1 - 0.013 15.3 0.0 3.8 7.4 0.0 2.6 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HATPase_c_3 PF13589.6 RLN20262.1 - 0.023 14.6 0.1 3.9 7.3 0.0 2.7 3 0 0 3 3 3 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ADH_zinc_N PF00107.26 RLN20262.1 - 0.08 12.9 5.0 2 8.4 0.3 3.1 3 0 0 3 3 3 0 Zinc-binding dehydrogenase adh_short PF00106.25 RLN20263.1 - 3e-21 75.8 0.1 4.2e-21 75.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN20263.1 - 9.3e-16 58.1 0.0 1.1e-15 57.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_hydro_32C PF08244.12 RLN20264.1 - 0.098 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 C terminal adh_short PF00106.25 RLN20265.1 - 6.8e-31 107.2 0.0 8.3e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN20265.1 - 3e-19 69.5 0.0 3.6e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 RLN20265.1 - 6.8e-05 22.5 0.1 0.0066 15.9 0.0 2.3 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 RLN20265.1 - 0.0015 18.4 0.2 0.0032 17.4 0.2 1.6 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 RLN20265.1 - 0.04 13.0 0.1 0.17 10.9 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 RLN20265.1 - 0.074 12.9 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding TFR_dimer PF04253.15 RLN20266.1 - 4.5e-22 78.4 0.0 7.8e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain CNTF PF01110.17 RLN20266.1 - 0.24 10.7 1.0 5.9 6.2 0.1 2.2 2 0 0 2 2 2 0 Ciliary neurotrophic factor TFR_dimer PF04253.15 RLN20267.1 - 4.6e-28 97.8 0.0 1.3e-27 96.3 0.0 1.8 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 RLN20267.1 - 1.7e-17 63.7 0.0 3.9e-17 62.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 RLN20267.1 - 6.4e-11 42.1 1.6 1.9e-10 40.6 0.0 2.2 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 RLN20267.1 - 0.00099 18.9 0.0 0.003 17.3 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 SUKH-4 PF14435.6 RLN20267.1 - 0.047 13.7 2.0 0.092 12.8 1.2 1.9 2 0 0 2 2 2 0 SUKH-4 immunity protein WXG100 PF06013.12 RLN20267.1 - 0.082 13.2 0.2 3.6 7.9 0.1 2.9 2 1 1 3 3 3 0 Proteins of 100 residues with WXG FoP_duplication PF13865.6 RLN20268.1 - 0.49 11.0 9.5 4.8 7.8 7.1 2.7 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Macoilin PF09726.9 RLN20268.1 - 9.1 4.7 6.0 14 4.0 6.0 1.4 1 0 0 1 1 1 0 Macoilin family Pkinase_Tyr PF07714.17 RLN20269.1 - 1.2e-43 149.2 0.0 3.3e-37 128.2 0.0 3.3 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN20269.1 - 7.9e-41 140.2 0.0 2.9e-37 128.5 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 RLN20269.1 - 0.00011 21.6 0.0 0.034 13.4 0.0 2.6 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 RLN20269.1 - 0.0017 18.3 0.2 0.0017 18.3 0.2 2.7 3 1 0 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN20269.1 - 0.014 14.2 0.1 0.049 12.4 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase DUF3254 PF11630.8 RLN20269.1 - 0.049 13.8 0.3 0.14 12.4 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) VPS9 PF02204.18 RLN20270.1 - 4e-23 81.6 0.0 8.4e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF4248 PF14053.6 RLN20270.1 - 0.097 12.7 0.1 4.5 7.4 0.0 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4248) PhyH PF05721.13 RLN20271.1 - 7e-55 186.6 0.1 8.4e-55 186.3 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ndc80_HEC PF03801.13 RLN20271.1 - 0.04 13.5 0.1 0.064 12.9 0.1 1.3 1 0 0 1 1 1 0 HEC/Ndc80p family Wyosine_form PF08608.12 RLN20271.1 - 0.079 13.3 0.3 0.79 10.1 0.0 2.2 2 0 0 2 2 2 0 Wyosine base formation Ufd2P_core PF10408.9 RLN20278.1 - 6.9e-25 87.7 0.0 1.2e-18 67.1 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin elongating factor core ZZ PF00569.17 RLN20278.1 - 1.3e-07 31.3 28.7 1.2e-06 28.3 10.6 3.6 3 0 0 3 3 3 2 Zinc finger, ZZ type C1_2 PF03107.16 RLN20278.1 - 0.0096 16.2 5.3 0.0096 16.2 5.3 3.4 3 0 0 3 3 3 1 C1 domain Nucleoside_tran PF01733.18 RLN20279.1 - 7.1e-17 61.7 6.0 8.4e-17 61.5 6.0 1.0 1 0 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 RLN20279.1 - 0.012 14.5 14.1 0.014 14.3 14.1 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Tmemb_170 PF10190.9 RLN20279.1 - 0.44 10.9 4.6 0.69 10.3 0.3 2.0 1 1 1 2 2 2 0 Putative transmembrane protein 170 Nucleoside_tran PF01733.18 RLN20280.1 - 1.2e-27 97.1 18.2 1.2e-27 97.1 18.2 2.3 2 1 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.16 RLN20280.1 - 0.025 13.5 45.9 0.39 9.6 10.7 3.2 1 1 1 2 2 2 0 Major Facilitator Superfamily Tudor_2 PF18104.1 RLN20280.1 - 0.071 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain Myb_DNA-binding PF00249.31 RLN20281.1 - 1.5e-10 41.1 0.0 2.8e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN20281.1 - 0.0066 16.7 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 RLN20282.1 - 7.2e-08 32.5 0.4 2e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain FB_lectin PF07367.11 RLN20282.1 - 0.072 13.0 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Fungal fruit body lectin zf-RING_2 PF13639.6 RLN20283.1 - 2.4e-09 37.4 11.5 5.3e-09 36.3 11.5 1.6 1 0 0 1 1 1 1 Ring finger domain PX PF00787.24 RLN20283.1 - 5.9e-09 35.9 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 PX domain zf-RING_11 PF17123.5 RLN20283.1 - 9.7e-07 28.4 3.5 9.7e-07 28.4 3.5 2.5 2 1 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 RLN20283.1 - 2.5e-05 24.5 11.2 6.9e-05 23.1 11.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 RLN20283.1 - 0.00012 22.1 2.3 0.00025 21.0 2.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RLN20283.1 - 0.00027 20.7 7.1 0.00057 19.7 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN20283.1 - 0.00066 19.6 9.2 0.0015 18.5 9.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RLN20283.1 - 0.0022 17.8 9.3 0.0051 16.6 9.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN20283.1 - 0.011 15.8 4.7 0.011 15.8 4.7 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RLN20283.1 - 0.011 15.5 13.7 0.042 13.7 13.7 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 RLN20283.1 - 0.079 13.2 6.8 0.72 10.1 6.8 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 RLN20283.1 - 0.42 10.5 11.6 1.3 8.9 11.6 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 WD40 PF00400.32 RLN20284.1 - 1.5e-30 104.7 13.4 1.5e-08 35.2 0.2 6.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN20284.1 - 1.6e-12 47.5 0.0 0.0097 16.2 0.0 4.5 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RLN20284.1 - 0.0019 18.1 0.0 0.94 9.3 0.0 2.5 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Myb_DNA-binding PF00249.31 RLN20285.1 - 4.9e-11 42.6 0.0 6.1e-10 39.1 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain PCNA_C PF02747.15 RLN20286.1 - 1.7e-23 83.2 0.0 1.9e-23 83.0 0.0 1.0 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Aa_trans PF01490.18 RLN20287.1 - 1.4e-71 241.4 20.5 1.8e-71 241.0 20.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1656 PF07869.12 RLN20287.1 - 0.015 15.3 4.5 0.039 14.0 0.5 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) SPC12 PF06645.13 RLN20287.1 - 0.082 13.0 1.4 0.29 11.3 0.1 2.6 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) OMPdecase PF00215.24 RLN20288.1 - 4.7e-30 104.9 0.0 1.3e-29 103.4 0.0 1.7 2 0 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 RLN20288.1 - 3.8e-14 52.5 0.2 8.5e-14 51.4 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Img2 PF05046.14 RLN20288.1 - 3.2e-11 43.4 0.0 8.1e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Pro-rich_19 PF15455.6 RLN20288.1 - 0.034 13.3 0.6 0.055 12.6 0.6 1.3 1 0 0 1 1 1 0 Proline-rich 19 Got1 PF04178.12 RLN20289.1 - 1.1e-16 61.2 13.4 1.4e-16 60.9 13.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.13 RLN20289.1 - 0.052 13.9 16.5 0.44 10.9 6.1 2.2 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) DUF2157 PF09925.9 RLN20289.1 - 0.32 10.8 8.5 0.43 10.4 8.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Anoctamin PF04547.12 RLN20289.1 - 6 5.6 5.5 1.9 7.2 2.8 1.5 1 1 0 1 1 1 0 Calcium-activated chloride channel adh_short PF00106.25 RLN20353.1 - 3.3e-50 170.3 0.0 4.2e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN20353.1 - 9.8e-34 116.9 0.0 1.3e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN20353.1 - 6.2e-14 52.3 0.0 1e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 RLN20354.1 - 8.7e-54 181.9 0.1 1.1e-53 181.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN20354.1 - 5.6e-37 127.5 0.0 7.6e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN20354.1 - 4.2e-13 49.6 1.4 5.2e-13 49.3 0.5 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 RLN20354.1 - 0.011 15.2 0.1 0.038 13.5 0.2 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUSP PF06337.12 RLN20355.1 - 0.00034 21.2 0.0 0.00065 20.3 0.0 1.4 1 0 0 1 1 1 1 DUSP domain PDZ PF00595.24 RLN20355.1 - 0.00069 19.9 0.1 0.027 14.8 0.0 2.6 2 0 0 2 2 2 1 PDZ domain zf-RING_2 PF13639.6 RLN20356.1 - 1.7e-10 41.0 12.2 2.5e-10 40.5 12.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RLN20356.1 - 1.2e-08 35.1 9.2 2.7e-08 34.0 9.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 RLN20356.1 - 1.4e-05 24.7 7.2 2.4e-05 24.0 7.2 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 RLN20356.1 - 3.6e-05 23.5 9.5 5.8e-05 22.9 9.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN20356.1 - 5.9e-05 23.0 7.5 0.00011 22.2 7.5 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RLN20356.1 - 0.00015 21.6 12.1 0.00022 21.0 12.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN20356.1 - 0.00017 21.3 12.5 0.00026 20.8 12.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN20356.1 - 0.00048 20.0 9.6 0.00079 19.3 9.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-HC5HC2H PF13771.6 RLN20356.1 - 0.00073 19.7 3.5 0.0015 18.8 3.5 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain Zn_ribbon_17 PF17120.5 RLN20356.1 - 0.0039 16.8 7.6 0.0063 16.1 7.6 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-HC5HC2H_2 PF13832.6 RLN20356.1 - 0.017 15.3 3.0 0.032 14.4 3.0 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-ANAPC11 PF12861.7 RLN20356.1 - 0.017 15.2 7.2 0.043 13.9 7.2 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 RLN20356.1 - 0.032 14.1 8.7 0.06 13.2 8.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 RLN20356.1 - 0.051 13.7 6.0 0.12 12.5 6.0 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 RLN20356.1 - 0.069 13.5 9.8 0.1 12.9 9.8 1.3 1 0 0 1 1 1 0 RING-like domain Pet100 PF09803.9 RLN20356.1 - 0.16 12.5 0.1 0.43 11.1 0.1 1.7 1 0 0 1 1 1 0 Pet100 DASH_Hsk3 PF08227.11 RLN20356.1 - 0.28 11.6 3.1 0.5 10.8 3.1 1.4 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like C1_2 PF03107.16 RLN20356.1 - 0.58 10.5 4.1 0.18 12.2 1.1 1.6 2 0 0 2 2 1 0 C1 domain zf-C3H2C3 PF17122.5 RLN20356.1 - 0.9 9.6 3.8 1.7 8.7 3.8 1.4 1 0 0 1 1 1 0 Zinc-finger RINGv PF12906.7 RLN20356.1 - 1.5 9.0 11.2 2.7 8.2 11.2 1.4 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 RLN20356.1 - 5.7 6.8 8.2 12 5.8 7.9 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 RLN20356.1 - 7.4 6.6 9.2 12 5.8 9.2 1.4 1 0 0 1 1 1 0 PHD-finger Spt5_N PF11942.8 RLN20357.1 - 0.21 12.6 2.3 0.39 11.7 2.3 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal ANAPC4_WD40 PF12894.7 RLN20358.1 - 0.0031 17.8 0.0 21 5.5 0.0 3.7 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain zf-CW PF07496.15 RLN20359.1 - 5.8e-41 138.3 45.2 3.8e-16 58.8 9.2 4.6 4 0 0 4 4 4 3 CW-type Zinc Finger PHD PF00628.29 RLN20359.1 - 8.8e-11 41.5 36.2 2.9e-07 30.3 0.3 6.7 6 0 0 6 6 6 4 PHD-finger zf-RING_2 PF13639.6 RLN20359.1 - 0.016 15.5 22.7 0.15 12.4 0.5 3.8 3 0 0 3 3 3 0 Ring finger domain CRT-like PF08627.10 RLN20360.1 - 4.3e-98 328.3 5.3 4.9e-98 328.2 5.3 1.0 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 RLN20360.1 - 2.4e-05 23.7 0.6 2.4e-05 23.7 0.6 1.6 2 0 0 2 2 2 1 UAA transporter family SLC35F PF06027.12 RLN20360.1 - 0.0021 17.6 2.4 0.0021 17.6 2.4 1.6 2 0 0 2 2 2 1 Solute carrier family 35 EamA PF00892.20 RLN20360.1 - 0.0072 16.5 4.0 0.0072 16.5 4.0 3.2 2 1 0 2 2 2 1 EamA-like transporter family Acyltransferase PF01553.21 RLN20361.1 - 4.7e-20 71.6 0.0 6.8e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 RLN20361.1 - 8.6e-13 48.2 0.0 1.7e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Pkinase PF00069.25 RLN20362.1 - 1.4e-62 211.5 0.0 1.9e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN20362.1 - 1.7e-30 106.2 0.0 2.6e-30 105.6 0.0 1.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN20362.1 - 2.4e-06 27.1 0.0 3.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 RLN20362.1 - 0.0039 16.7 0.0 0.0065 16.0 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 RLN20362.1 - 0.0091 15.4 1.0 0.014 14.8 1.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN20362.1 - 0.0095 14.8 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN20362.1 - 0.023 14.6 0.3 0.037 13.9 0.3 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family HEAT_EZ PF13513.6 RLN20362.1 - 0.051 14.1 0.0 12 6.6 0.0 3.3 3 0 0 3 3 3 0 HEAT-like repeat RIO1 PF01163.22 RLN20362.1 - 0.055 13.1 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family RNA_pol_Rpb5_C PF01191.19 RLN20362.1 - 0.2 11.6 0.8 5.1 7.0 0.1 2.6 3 0 0 3 3 3 0 RNA polymerase Rpb5, C-terminal domain DUF4360 PF14273.6 RLN20365.1 - 1.8e-38 132.2 0.5 2.4e-38 131.8 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) PseudoU_synth_2 PF00849.22 RLN20366.1 - 2.4e-26 92.7 0.0 3.6e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase PIN_12 PF16289.5 RLN20367.1 - 0.058 13.9 0.0 0.063 13.8 0.0 1.1 1 0 0 1 1 1 0 PIN domain PAN_4 PF14295.6 RLN20370.1 - 3.4e-41 138.9 35.8 8.5e-12 44.8 1.8 4.4 4 0 0 4 4 4 4 PAN domain PAN_1 PF00024.26 RLN20370.1 - 6.8e-23 80.4 16.2 1.8e-06 27.8 1.9 4.2 2 2 2 4 4 4 4 PAN domain PAN_2 PF08276.11 RLN20370.1 - 0.0037 17.4 37.7 0.63 10.2 2.2 4.3 4 0 0 4 4 4 4 PAN-like domain Pkinase_Tyr PF07714.17 RLN20371.1 - 2.7e-45 154.7 0.0 1.6e-36 126.0 0.0 3.9 3 1 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 RLN20371.1 - 1.4e-43 149.2 0.0 8.3e-36 123.7 0.0 2.7 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 RLN20371.1 - 0.033 13.6 0.0 0.076 12.3 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Calici_coat_C PF08435.11 RLN20371.1 - 0.085 12.4 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal PGAP1 PF07819.13 RLN20372.1 - 0.011 15.5 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 RLN20372.1 - 0.011 16.3 0.5 0.011 16.3 0.5 3.9 4 0 0 4 4 4 0 Alpha/beta hydrolase family DUF676 PF05057.14 RLN20372.1 - 0.082 12.4 0.1 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Putative serine esterase (DUF676) LCAT PF02450.15 RLN20372.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Arm PF00514.23 RLN20372.1 - 1.3 9.1 10.2 33 4.7 0.0 5.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Pkinase PF00069.25 RLN20373.1 - 9.3e-48 162.9 0.0 1.7e-47 162.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN20373.1 - 3.8e-42 144.4 0.0 5.4e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Podoplanin PF05808.11 RLN20373.1 - 0.00058 20.0 1.4 0.0011 19.1 1.4 1.4 1 0 0 1 1 1 1 Podoplanin Adeno_E3_CR2 PF02439.15 RLN20373.1 - 0.025 14.3 0.6 0.051 13.3 0.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CTC1 PF15489.6 RLN20373.1 - 0.052 11.1 0.0 0.075 10.5 0.0 1.1 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 DUF3147 PF11345.8 RLN20373.1 - 0.057 13.8 0.2 0.11 12.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3147) DUF1180 PF06679.12 RLN20373.1 - 0.066 13.6 3.6 0.072 13.5 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Haspin_kinase PF12330.8 RLN20373.1 - 0.089 11.7 0.2 0.27 10.1 0.2 1.8 1 1 0 1 1 1 0 Haspin like kinase domain EphA2_TM PF14575.6 RLN20373.1 - 0.14 13.0 0.0 0.38 11.7 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 RLN20373.1 - 0.16 11.9 0.1 0.35 10.8 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family MtrF PF09472.10 RLN20373.1 - 1.1 8.7 5.3 2.3 7.7 5.3 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) MGC-24 PF05283.11 RLN20373.1 - 9.6 6.7 9.3 0.27 11.7 2.7 1.7 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PAN_4 PF14295.6 RLN20374.1 - 2.1e-41 139.6 38.3 6.1e-11 42.1 5.2 4.5 4 0 0 4 4 4 4 PAN domain PAN_1 PF00024.26 RLN20374.1 - 4.3e-24 84.3 15.5 1.1e-05 25.3 0.2 4.2 3 1 1 4 4 4 4 PAN domain PAN_2 PF08276.11 RLN20374.1 - 0.0022 18.1 41.0 0.19 11.8 5.3 4.3 4 0 0 4 4 4 4 PAN-like domain zf-RING_2 PF13639.6 RLN20375.1 - 4.5e-12 46.1 6.0 7.4e-12 45.4 6.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RLN20375.1 - 2.8e-08 33.9 4.0 5.8e-08 32.9 4.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 RLN20375.1 - 1.2e-07 31.3 2.4 2.3e-07 30.4 2.4 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RLN20375.1 - 3.2e-06 26.9 5.1 7.1e-06 25.8 5.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN20375.1 - 4.2e-06 26.5 4.6 7.2e-06 25.8 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN20375.1 - 1.9e-05 24.6 4.9 3.5e-05 23.7 4.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN20375.1 - 2.6e-05 24.1 2.3 4.3e-05 23.4 2.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RLN20375.1 - 3e-05 23.8 2.6 4.8e-05 23.1 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RLN20375.1 - 0.00018 21.5 2.7 0.00048 20.1 2.7 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PX PF00787.24 RLN20375.1 - 0.0012 18.8 0.0 0.0029 17.6 0.0 1.7 1 1 0 1 1 1 1 PX domain Prok-RING_4 PF14447.6 RLN20375.1 - 0.0048 16.7 5.6 0.0081 16.0 5.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 RLN20375.1 - 0.0067 16.6 2.9 0.016 15.4 2.9 1.6 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 RLN20375.1 - 0.017 15.2 2.2 0.017 15.2 2.2 1.9 2 1 0 2 2 2 0 RING-variant domain Zn_ribbon_17 PF17120.5 RLN20375.1 - 0.081 12.6 3.5 0.16 11.6 3.5 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 RLN20375.1 - 0.13 12.4 2.0 0.31 11.1 2.0 1.6 1 0 0 1 1 1 0 Zinc-finger zf-RING_2 PF13639.6 RLN20376.1 - 8.2e-11 42.1 11.1 1.3e-10 41.5 11.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RLN20376.1 - 3e-07 30.6 9.1 6.5e-07 29.5 9.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 RLN20376.1 - 1.3e-05 24.9 7.3 2.9e-05 23.7 7.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 RLN20376.1 - 5.3e-05 23.2 2.9 0.00012 22.0 2.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PX PF00787.24 RLN20376.1 - 6.5e-05 22.9 0.9 0.00015 21.7 0.2 1.9 2 1 0 2 2 2 1 PX domain zf-C3HC4_3 PF13920.6 RLN20376.1 - 9.9e-05 22.1 6.6 0.00016 21.4 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN20376.1 - 0.00018 21.3 12.9 0.00043 20.1 12.9 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN20376.1 - 0.00022 21.0 10.1 0.00038 20.3 10.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN20376.1 - 0.00024 21.0 9.0 0.0005 20.0 9.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN20376.1 - 0.0017 18.3 7.6 0.0028 17.6 7.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RLN20376.1 - 0.014 15.2 8.5 0.026 14.4 8.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 RLN20376.1 - 0.098 12.7 4.0 0.22 11.6 4.0 1.5 1 0 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 RLN20376.1 - 0.17 12.1 6.9 0.5 10.6 6.9 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 RLN20376.1 - 0.32 11.1 6.6 0.78 9.9 6.6 1.7 1 1 0 1 1 1 0 RING-variant domain Abhydrolase_1 PF00561.20 RLN20378.1 - 4e-10 39.8 0.0 1.3e-09 38.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN20378.1 - 5.1e-05 24.0 0.0 8.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Tubulin PF00091.25 RLN20379.1 - 6.8e-43 147.2 0.0 1.3e-42 146.3 0.0 1.4 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Myb_DNA-binding PF00249.31 RLN20380.1 - 9.8e-11 41.7 0.0 1.5e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN20380.1 - 0.021 15.1 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain AFT PF08731.11 RLN20381.1 - 0.091 13.2 0.9 0.16 12.4 0.9 1.7 1 1 0 1 1 1 0 Transcription factor AFT Nop14 PF04147.12 RLN20381.1 - 1.6 6.9 6.7 1.8 6.7 6.7 1.0 1 0 0 1 1 1 0 Nop14-like family cwf21 PF08312.12 RLN20382.1 - 9.4e-07 28.9 11.0 9.4e-07 28.9 11.0 2.9 3 0 0 3 3 3 1 cwf21 domain Phage_holin_3_6 PF07332.11 RLN20383.1 - 0.21 11.6 3.1 0.45 10.6 3.1 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III LRR_8 PF13855.6 RLN20384.1 - 0.0024 17.6 0.1 0.4 10.5 0.0 3.4 3 2 1 4 4 4 1 Leucine rich repeat CDP-OH_P_transf PF01066.21 RLN20384.1 - 0.14 12.9 3.6 16 6.3 0.0 3.8 3 1 0 3 3 3 0 CDP-alcohol phosphatidyltransferase Pkinase PF00069.25 RLN20391.1 - 3.1e-50 171.0 0.0 4.6e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN20391.1 - 3.4e-48 164.2 0.0 4.4e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RLN20391.1 - 1.9e-06 27.1 0.0 2.8e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RLN20391.1 - 0.0074 15.7 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN20391.1 - 0.0077 16.2 0.1 0.017 15.0 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 RLN20392.1 - 6.5e-49 166.7 0.0 9.3e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN20392.1 - 5.8e-45 153.6 0.0 7.7e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RLN20392.1 - 0.012 14.6 0.0 0.017 14.0 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Carb_anhydrase PF00194.21 RLN20393.1 - 1.2e-37 129.8 0.0 6.9e-36 124.1 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Neur_chan_memb PF02932.16 RLN20405.1 - 3.2 7.8 5.2 3.8 7.5 5.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CENP-H PF05837.12 RLN20406.1 - 0.01 16.3 0.4 0.01 16.3 0.4 3.1 2 1 2 4 4 4 0 Centromere protein H (CENP-H) DUF641 PF04859.12 RLN20406.1 - 0.013 15.9 0.7 0.048 14.0 0.7 2.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Leu_zip PF15294.6 RLN20406.1 - 0.31 10.5 8.5 0.85 9.1 2.6 2.3 2 0 0 2 2 2 0 Leucine zipper FPP PF05911.11 RLN20406.1 - 0.98 7.5 9.0 0.24 9.5 1.4 2.2 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil TACC_C PF05010.14 RLN20406.1 - 2 8.1 7.5 0.5 10.1 1.1 2.6 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal UPF0242 PF06785.11 RLN20406.1 - 3.3 7.8 9.0 4.5 7.3 1.3 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 RLN20406.1 - 4 7.3 15.4 0.97 9.2 0.2 3.9 4 0 0 4 4 4 0 Septum formation initiator DUF948 PF06103.11 RLN20406.1 - 7.1 7.0 5.9 4.1 7.7 1.5 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HMMR_N PF15905.5 RLN20406.1 - 7.7 5.9 13.5 6.7 6.1 5.2 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal ADIP PF11559.8 RLN20406.1 - 8.3 6.5 17.4 0.26 11.3 4.0 3.2 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding TFIIE-A_C PF11521.8 RLN20417.1 - 0.0087 16.3 5.8 0.0087 16.3 5.8 2.7 1 1 2 3 3 3 2 C-terminal general transcription factor TFIIE alpha BUD22 PF09073.10 RLN20417.1 - 0.041 13.2 12.9 0.048 13.0 12.9 1.0 1 0 0 1 1 1 0 BUD22 DUF4604 PF15377.6 RLN20417.1 - 2.2 8.7 16.8 3.3 8.1 16.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RSB_motif PF16294.5 RLN20417.1 - 2.7 8.3 16.9 5.4 7.3 1.6 2.1 2 0 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif WD40 PF00400.32 RLN20418.1 - 9.4e-19 67.4 6.6 0.00054 20.7 0.1 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN20418.1 - 6.8e-15 55.1 0.0 3.8e-05 23.9 0.0 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 RLN20418.1 - 5.7e-06 26.6 2.6 13 6.4 0.1 5.8 6 0 0 6 6 6 1 PQQ-like domain Ge1_WD40 PF16529.5 RLN20418.1 - 0.00032 19.8 0.3 0.54 9.2 0.0 2.9 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 RLN20418.1 - 0.072 13.1 0.0 7.2 6.7 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 RLN20418.1 - 0.083 12.6 0.0 7.8 6.3 0.0 2.6 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature IKI3 PF04762.12 RLN20418.1 - 0.1 10.6 0.0 0.14 10.1 0.0 1.1 1 0 0 1 1 1 0 IKI3 family PB1 PF00564.24 RLN20421.1 - 2.1e-09 37.2 0.0 6.4e-09 35.6 0.0 1.8 2 1 0 2 2 2 1 PB1 domain V-ATPase_G_2 PF16999.5 RLN20421.1 - 0.28 11.6 8.2 0.17 12.3 3.6 2.6 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit N6-adenineMlase PF10237.9 RLN20422.1 - 8.6e-52 175.2 2.3 2.3e-26 92.5 0.1 2.4 1 1 1 2 2 2 2 Probable N6-adenine methyltransferase zf-HC2 PF13490.6 RLN20422.1 - 0.0022 18.2 7.1 0.22 11.8 1.2 2.7 2 0 0 2 2 2 2 Putative zinc-finger Thioredoxin_15 PF18403.1 RLN20422.1 - 0.048 13.6 0.0 0.65 9.9 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain UPF0020 PF01170.18 RLN20422.1 - 0.05 13.3 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Bmp PF02608.14 RLN20422.1 - 0.054 12.5 0.0 1.1 8.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter substrate-binding protein PnrA-like FERM_M PF00373.18 RLN20422.1 - 0.057 13.8 3.6 1.5 9.2 0.2 2.3 2 0 0 2 2 2 0 FERM central domain DUF43 PF01861.16 RLN20422.1 - 0.12 11.6 0.2 1.2 8.3 0.1 2.1 2 0 0 2 2 2 0 Branched-chain polyamine synthase A C-terminal domain LPD26 PF18842.1 RLN20422.1 - 0.14 12.2 1.2 13 5.8 0.1 2.4 2 0 0 2 2 2 0 Large polyvalent protein associated domain 26 Crust_neuro_H PF03858.13 RLN20422.1 - 0.44 11.4 2.0 11 6.9 0.1 2.6 2 0 0 2 2 2 0 Crustacean neurohormone H DotU PF09850.9 RLN20443.1 - 0.012 15.4 0.5 0.084 12.6 0.0 2.0 2 0 0 2 2 2 0 Type VI secretion system protein DotU Kinesin_assoc PF16183.5 RLN20443.1 - 0.015 15.4 0.2 0.019 15.1 0.2 1.2 1 0 0 1 1 1 0 Kinesin-associated MMR_HSR1 PF01926.23 RLN20444.1 - 1.2e-12 47.9 0.0 6.9e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase HSCB_C PF07743.13 RLN20444.1 - 1.2e-07 32.1 0.5 1.2e-07 32.1 0.5 1.9 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain RsgA_GTPase PF03193.16 RLN20444.1 - 1.2e-05 25.3 0.1 0.0026 17.7 0.1 2.4 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 RLN20444.1 - 0.00015 21.3 0.0 0.0015 18.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 RLN20444.1 - 0.0089 16.1 0.2 0.032 14.3 0.1 1.8 1 1 0 1 1 1 1 Dynamin family Roc PF08477.13 RLN20444.1 - 0.0097 16.1 0.0 0.18 12.0 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 RLN20444.1 - 0.019 14.3 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Septin RNA_helicase PF00910.22 RLN20444.1 - 0.029 14.7 0.0 9.8 6.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 RLN20444.1 - 0.057 13.8 0.1 0.35 11.2 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain DUF3336 PF11815.8 RLN20445.1 - 0.031 14.0 0.2 0.068 12.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3336) ubiquitin PF00240.23 RLN20446.1 - 8e-07 28.7 0.2 7.7e-06 25.6 0.2 2.0 1 1 0 1 1 1 1 Ubiquitin family SURF6 PF04935.12 RLN20460.1 - 1.5e-20 73.9 47.5 1.5e-20 73.9 47.5 2.6 1 1 1 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 RLN20460.1 - 9.3e-14 51.8 3.6 9.3e-14 51.8 3.6 6.7 5 2 0 5 5 5 1 60S ribosome biogenesis protein Rrp14 CLPTM1 PF05602.12 RLN20461.1 - 4.1e-80 269.9 0.0 5.8e-80 269.4 0.0 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Dynamin_M PF01031.20 RLN20462.1 - 6e-09 35.5 0.0 6.7e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 Dynamin central region GCP_N_terminal PF17681.1 RLN20462.1 - 0.17 11.5 2.0 0.47 10.0 0.3 2.2 2 0 0 2 2 2 0 Gamma tubulin complex component N-terminal DUF3072 PF11272.8 RLN20463.1 - 0.015 15.2 0.7 0.015 15.2 0.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3072) CorA PF01544.18 RLN20463.1 - 8.8 5.5 9.9 1.3 8.3 0.1 2.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Bromodomain PF00439.25 RLN20488.1 - 6.2e-18 64.7 0.0 1.1e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 RLN20488.1 - 1.2e-09 37.9 11.7 1.2e-09 37.9 11.7 2.4 2 1 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 RLN20488.1 - 0.02 14.4 4.9 0.056 13.0 4.9 1.8 1 0 0 1 1 1 0 PHD-finger DNA_ligase_A_N PF04675.14 RLN20489.1 - 2.9e-41 141.7 0.3 1.7e-40 139.2 0.1 2.2 2 0 0 2 2 2 1 DNA ligase N terminus Presenilin PF01080.17 RLN20489.1 - 0.0033 16.2 1.7 0.0033 16.2 1.7 2.3 2 0 0 2 2 2 1 Presenilin KNOX1 PF03790.13 RLN20489.1 - 0.08 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 KNOX1 domain RNase_H2-Ydr279 PF09468.10 RLN20490.1 - 6.9e-09 36.1 0.0 1.4e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 RLN20490.1 - 9.2e-06 25.8 0.0 2.4e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain C2 PF00168.30 RLN20492.1 - 0.00034 20.9 0.0 5.2 7.4 0.0 3.9 3 0 0 3 3 3 3 C2 domain APC_u14 PF16635.5 RLN20492.1 - 0.12 13.0 1.2 0.35 11.4 1.2 1.7 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr W2 PF02020.18 RLN20493.1 - 5.6e-17 61.6 0.3 1.5e-16 60.3 0.3 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon DUF5401 PF17380.2 RLN20493.1 - 0.24 9.4 9.5 0.33 9.0 9.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) RR_TM4-6 PF06459.12 RLN20493.1 - 1.8 8.3 10.0 2.7 7.7 10.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ARL2_Bind_BART PF11527.8 RLN20494.1 - 1.4e-17 63.9 4.1 2.1e-17 63.3 4.1 1.2 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Pro_isomerase PF00160.21 RLN20495.1 - 1.3e-38 132.7 0.2 3.8e-38 131.2 0.2 1.6 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Aldedh PF00171.22 RLN20496.1 - 6.2e-18 64.6 0.0 7.9e-18 64.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ank_2 PF12796.7 RLN20498.1 - 2e-35 121.2 8.2 2.9e-09 37.4 0.2 6.2 4 1 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN20498.1 - 5.7e-33 112.9 11.4 5.9e-05 23.5 0.1 10.0 7 4 2 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN20498.1 - 3.5e-26 90.9 27.4 0.0044 17.3 0.2 13.8 6 2 9 15 15 15 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN20498.1 - 2.6e-20 70.3 3.9 3.5 8.5 0.0 13.4 11 3 3 14 14 14 3 Ankyrin repeat Ank PF00023.30 RLN20498.1 - 2.3e-05 24.6 0.9 1.4e+02 3.1 0.0 8.8 4 3 3 7 7 7 0 Ankyrin repeat RmlD_sub_bind PF04321.17 RLN20498.1 - 0.0053 15.9 0.8 1.8 7.6 0.2 3.2 2 1 1 3 3 3 1 RmlD substrate binding domain GST_N_5 PF18485.1 RLN20498.1 - 0.1 13.0 0.4 3.7 8.0 0.0 3.7 4 0 0 4 4 4 0 Glutathione S-transferase, N-terminal domain DUF1979 PF09322.10 RLN20498.1 - 0.15 12.0 0.0 27 4.8 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF1979) Aa_trans PF01490.18 RLN20499.1 - 2.9e-38 131.7 29.1 4.7e-38 131.0 29.1 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CTP_transf_like PF01467.26 RLN20504.1 - 0.00011 22.4 0.0 0.00085 19.5 0.0 2.4 2 1 0 2 2 2 1 Cytidylyltransferase-like CinA PF02464.17 RLN20504.1 - 0.002 17.7 0.7 0.0041 16.7 0.2 1.8 2 0 0 2 2 2 1 Competence-damaged protein JAMP PF05571.12 RLN20505.1 - 0.41 10.2 3.2 0.6 9.7 3.2 1.1 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein DUF3275 PF11679.8 RLN20505.1 - 0.68 9.9 3.8 1 9.3 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) ADK_lid PF05191.14 RLN20505.1 - 1.7 8.7 6.8 0.28 11.2 2.3 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid Sulfate_transp PF00916.20 RLN20507.1 - 7.4e-84 281.7 14.7 7.8e-44 150.0 4.5 2.4 2 0 0 2 2 2 2 Sulfate permease family MscL PF01741.18 RLN20507.1 - 1.5e-38 131.8 0.8 2.5e-21 76.2 0.0 3.1 3 1 1 4 4 4 2 Large-conductance mechanosensitive channel, MscL STAS PF01740.21 RLN20507.1 - 4.2e-14 52.2 0.0 9.6e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 RLN20507.1 - 0.0011 19.4 4.5 0.0011 19.4 4.5 2.8 2 0 0 2 2 2 1 Molybdate transporter of MFS superfamily CobT PF06213.12 RLN20507.1 - 0.0017 17.8 4.3 0.0017 17.8 4.3 2.1 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT STAS_2 PF13466.6 RLN20507.1 - 0.0035 17.6 0.1 0.011 16.0 0.1 1.9 1 0 0 1 1 1 1 STAS domain TM_helix PF05552.12 RLN20507.1 - 0.042 13.8 0.4 0.17 11.9 0.4 2.1 1 0 0 1 1 1 0 Conserved TM helix LppA PF16708.5 RLN20507.1 - 0.083 12.8 0.5 0.25 11.2 0.5 1.8 1 0 0 1 1 1 0 Lipoprotein confined to pathogenic Mycobacterium CoA_binding_3 PF13727.6 RLN20507.1 - 1.4 8.9 5.0 0.37 10.8 0.2 2.5 3 0 0 3 3 3 0 CoA-binding domain Exo_endo_phos PF03372.23 RLN20508.1 - 6.6e-05 22.5 0.0 0.00019 21.0 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family IQ PF00612.27 RLN20508.1 - 0.00012 21.6 2.7 0.037 13.8 0.1 2.6 2 0 0 2 2 2 2 IQ calmodulin-binding motif C2 PF00168.30 RLN20509.1 - 1.7e-101 333.4 0.0 1.9e-16 60.2 0.0 9.1 9 0 0 9 9 9 8 C2 domain Ferlin_C PF16165.5 RLN20509.1 - 0.00022 21.2 3.1 0.00057 19.9 0.2 3.0 2 1 0 2 2 2 1 Ferlin C-terminus FerI PF08151.12 RLN20509.1 - 0.00029 20.9 0.0 0.0017 18.4 0.0 2.4 1 0 0 1 1 1 1 FerI (NUC094) domain RRN9 PF10680.9 RLN20509.1 - 0.16 12.3 0.2 0.46 10.8 0.2 1.8 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor CEP76-C2 PF15627.6 RLN20509.1 - 0.17 11.4 0.0 0.99 9.0 0.0 2.3 2 0 0 2 2 2 0 CEP76 C2 domain U3_snoRNA_assoc PF08297.11 RLN20509.1 - 0.28 11.9 3.1 0.7 10.6 0.2 2.9 2 0 0 2 2 2 0 U3 snoRNA associated CTP_transf_like PF01467.26 RLN20510.1 - 8.1e-06 26.1 0.0 7.6e-05 22.9 0.0 2.5 2 1 0 2 2 2 1 Cytidylyltransferase-like CinA PF02464.17 RLN20510.1 - 0.002 17.7 0.7 0.0042 16.7 0.2 1.8 2 0 0 2 2 2 1 Competence-damaged protein LTV PF04180.14 RLN20511.1 - 0.093 12.4 0.0 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 Low temperature viability protein AATase PF07247.12 RLN20512.1 - 9.3e-07 27.8 0.0 3.2e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 RLN20512.1 - 0.028 13.1 0.0 0.045 12.4 0.0 1.2 1 0 0 1 1 1 0 Condensation domain Sulfate_transp PF00916.20 RLN20513.1 - 3.4e-36 124.8 23.8 4.8e-36 124.3 23.8 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS_2 PF13466.6 RLN20513.1 - 1.5e-07 31.6 0.7 1.5e-07 31.6 0.7 2.1 2 0 0 2 2 2 1 STAS domain STAS PF01740.21 RLN20513.1 - 0.0013 18.3 0.1 0.0037 16.9 0.0 1.7 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 RLN20513.1 - 0.019 15.3 4.4 0.019 15.3 4.4 4.2 4 1 0 4 4 4 0 Molybdate transporter of MFS superfamily MscL PF01741.18 RLN20514.1 - 1.6e-15 57.4 0.6 2.1e-15 57.1 0.6 1.2 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL zf-ribbon_3 PF13248.6 RLN20514.1 - 0.00015 21.0 2.4 0.00021 20.6 2.4 1.2 1 0 0 1 1 1 1 zinc-ribbon domain UPF0547 PF10571.9 RLN20514.1 - 0.0011 19.0 3.7 0.0017 18.4 3.7 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 DZR PF12773.7 RLN20514.1 - 0.022 14.8 1.2 0.034 14.2 1.2 1.2 1 0 0 1 1 1 0 Double zinc ribbon C1_1 PF00130.22 RLN20514.1 - 0.075 12.9 1.2 0.12 12.3 1.2 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF983 PF06170.12 RLN20514.1 - 1.1 9.7 3.2 4.3 7.8 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF983) Sulfate_transp PF00916.20 RLN20515.1 - 1.4e-77 261.0 20.1 6.3e-41 140.4 0.9 2.3 2 0 0 2 2 2 2 Sulfate permease family STAS PF01740.21 RLN20515.1 - 4.1e-10 39.3 0.2 6.7e-10 38.6 0.2 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 RLN20515.1 - 0.016 15.6 5.5 0.016 15.6 5.5 3.5 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily WD40 PF00400.32 RLN20516.1 - 3.3e-06 27.7 0.2 0.069 14.0 0.0 3.5 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN20516.1 - 0.00089 19.5 0.0 1.5 9.2 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 RLN20516.1 - 0.046 12.8 0.0 10 5.1 0.0 2.4 2 0 0 2 2 2 0 Coatomer WD associated region Sec7 PF01369.20 RLN20517.1 - 9.1e-32 110.2 0.0 1.2e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Sec7 domain Pkinase PF00069.25 RLN20518.1 - 3.4e-62 210.2 0.0 5.3e-62 209.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN20518.1 - 6.5e-24 84.6 0.0 1.1e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase NAD_binding_10 PF13460.6 RLN20518.1 - 4.2e-08 33.3 0.0 1.3e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 RLN20518.1 - 1.1e-07 31.5 0.1 4.1e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 RLN20518.1 - 2.7e-05 23.4 0.4 0.0001 21.5 0.0 2.1 3 0 0 3 3 3 1 RmlD substrate binding domain WW PF00397.26 RLN20518.1 - 0.00035 20.6 0.1 0.00098 19.2 0.1 1.8 1 0 0 1 1 1 1 WW domain GDP_Man_Dehyd PF16363.5 RLN20518.1 - 0.022 14.2 0.0 0.32 10.4 0.0 2.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Haspin_kinase PF12330.8 RLN20518.1 - 0.044 12.7 0.1 0.074 12.0 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 RLN20518.1 - 0.05 12.9 0.6 0.12 11.7 0.6 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN20518.1 - 0.096 12.6 0.2 0.32 10.9 0.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family SnoaL_2 PF12680.7 RLN20518.1 - 0.13 12.9 2.2 0.19 12.4 0.3 2.4 2 0 0 2 2 2 0 SnoaL-like domain Stealth_CR2 PF11380.8 RLN20519.1 - 4.9e-36 123.2 0.0 1.1e-35 122.1 0.0 1.6 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 RLN20519.1 - 2.8e-12 46.3 3.7 5.2e-12 45.5 3.7 1.5 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 RLN20519.1 - 3.4e-05 23.5 0.0 7.7e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 RLN20519.1 - 0.0012 18.7 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Stealth_CR2 PF11380.8 RLN20520.1 - 1.7e-34 118.2 0.0 7.9e-34 116.1 0.0 2.0 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 RLN20520.1 - 6.9e-13 48.3 2.0 1.7e-12 47.1 2.0 1.7 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 RLN20520.1 - 8.4e-10 38.2 0.0 2e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 RLN20520.1 - 2.4e-09 36.9 0.0 5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Apt1 PF10351.9 RLN20521.1 - 6.4e-27 94.6 0.0 6.4e-27 94.6 0.0 1.8 2 0 0 2 2 2 1 Golgi-body localisation protein domain Ribosomal_L30_N PF08079.12 RLN20522.1 - 5.9e-24 84.1 9.9 5.9e-24 84.1 9.9 1.5 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 RLN20522.1 - 6.3e-22 77.2 2.0 1.2e-21 76.3 2.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Hydrolase_4 PF12146.8 RLN20524.1 - 2.2e-07 30.4 0.0 0.00047 19.5 0.0 2.0 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 RLN20524.1 - 0.00016 21.2 0.0 0.0091 15.5 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 RLN20524.1 - 0.00022 20.9 0.0 0.078 12.6 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold UPF0242 PF06785.11 RLN20525.1 - 0.29 11.2 7.3 0.48 10.5 7.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cellulase PF00150.18 RLN20528.1 - 0.00012 21.6 0.1 0.00017 21.1 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ras PF00071.22 RLN20536.1 - 2.3e-09 37.1 0.1 5.2e-05 22.9 0.0 2.5 2 1 0 2 2 2 2 Ras family Roc PF08477.13 RLN20536.1 - 3.1e-09 37.1 0.1 0.0019 18.4 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN20536.1 - 6.4e-05 22.5 0.0 0.08 12.4 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RLN20536.1 - 0.00012 22.1 0.0 0.00062 19.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RLN20536.1 - 0.00025 21.5 0.1 0.00046 20.6 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 RLN20536.1 - 0.0037 17.2 0.0 0.0063 16.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.27 RLN20536.1 - 0.0041 17.6 0.0 0.0082 16.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter GTP_EFTU PF00009.27 RLN20536.1 - 0.005 16.4 0.1 0.048 13.2 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.18 RLN20536.1 - 0.0067 15.7 0.0 0.01 15.1 0.0 1.1 1 0 0 1 1 1 1 Septin AAA_22 PF13401.6 RLN20536.1 - 0.0078 16.5 0.0 0.029 14.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 RLN20536.1 - 0.0088 16.0 0.4 0.015 15.2 0.4 1.3 1 0 0 1 1 1 1 RsgA GTPase G-alpha PF00503.20 RLN20536.1 - 0.0098 15.1 0.0 2.1 7.4 0.0 2.1 2 0 0 2 2 2 1 G-protein alpha subunit MCM PF00493.23 RLN20536.1 - 0.011 14.8 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_29 PF13555.6 RLN20536.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN20536.1 - 0.013 16.0 0.2 0.021 15.3 0.2 1.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 RLN20536.1 - 0.034 13.9 0.0 0.079 12.7 0.0 1.6 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 RLN20536.1 - 0.048 13.5 0.1 0.077 12.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 RLN20536.1 - 0.058 13.9 0.4 0.096 13.2 0.4 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RLN20536.1 - 0.06 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RLN20536.1 - 0.081 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 RLN20536.1 - 0.085 13.3 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 RLN20536.1 - 0.092 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 RLN20536.1 - 0.13 12.7 0.1 0.21 12.0 0.1 1.3 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 RLN20536.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRPRB PF09439.10 RLN20536.1 - 0.16 11.4 0.0 5.6 6.4 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 RLN20536.1 - 0.17 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) cobW PF02492.19 RLN20536.1 - 0.25 10.9 0.0 0.48 10.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Shisa PF13908.6 RLN20537.1 - 0.0054 17.0 0.5 0.0054 17.0 0.5 3.2 2 1 1 3 3 3 1 Wnt and FGF inhibitory regulator TMEM51 PF15345.6 RLN20537.1 - 0.012 15.5 0.0 0.012 15.5 0.0 2.6 3 0 0 3 3 3 0 Transmembrane protein 51 WBP-1 PF11669.8 RLN20537.1 - 0.024 15.3 2.2 0.024 15.3 2.2 2.2 1 1 1 2 2 2 0 WW domain-binding protein 1 Rhabdo_glycop PF00974.18 RLN20537.1 - 0.029 12.8 0.6 0.043 12.3 0.6 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Mucin PF01456.17 RLN20537.1 - 0.4 10.7 0.1 0.4 10.7 0.1 3.1 3 1 0 3 3 3 0 Mucin-like glycoprotein DUF4381 PF14316.6 RLN20537.1 - 3.2 8.0 9.2 0.17 12.1 3.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 RLN20537.1 - 3.7 8.5 5.7 14 6.6 5.7 2.2 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Big_7 PF17957.1 RLN20538.1 - 0.00023 21.9 0.0 0.066 14.0 0.0 2.8 2 0 0 2 2 2 2 Bacterial Ig domain BiPBP_C PF06832.12 RLN20538.1 - 0.004 17.2 0.0 0.021 14.9 0.0 2.1 2 0 0 2 2 2 1 Penicillin-Binding Protein C-terminus Family TPR_2 PF07719.17 RLN20539.1 - 6.8e-06 25.8 4.6 0.0001 22.1 0.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN20539.1 - 1.8e-05 24.3 1.9 0.00045 19.9 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN20539.1 - 0.0024 18.0 2.4 0.034 14.4 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN20539.1 - 0.0027 17.3 1.5 0.0074 16.0 0.6 2.2 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.6 RLN20539.1 - 0.003 17.8 2.7 0.003 17.8 2.7 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN20539.1 - 0.05 14.3 0.3 0.05 14.3 0.3 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 RLN20539.1 - 0.058 13.4 0.9 0.54 10.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN20539.1 - 0.12 12.3 1.8 0.25 11.3 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN20539.1 - 6.6 7.8 14.2 5.1 8.2 0.5 3.8 2 1 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.32 RLN20540.1 - 3.1e-12 46.8 0.0 0.11 13.5 0.0 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat PCP_red PF08369.10 RLN20540.1 - 0.0001 22.4 3.7 0.00019 21.6 3.7 1.5 1 0 0 1 1 1 1 Proto-chlorophyllide reductase 57 kD subunit F-actin_cap_A PF01267.17 RLN20541.1 - 3.2e-54 184.1 0.0 4.6e-43 147.6 0.0 2.9 2 1 0 2 2 2 2 F-actin capping protein alpha subunit zinc_ribbon_16 PF17034.5 RLN20547.1 - 6.3e-19 68.4 22.3 2.4e-14 53.6 7.4 3.2 3 1 0 3 3 3 2 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 RLN20547.1 - 0.0072 15.9 11.8 0.0072 15.9 11.8 3.1 4 1 0 4 4 4 1 Zinc-ribbon, C4HC2 type LRR_6 PF13516.6 RLN20548.1 - 3.5e-09 36.0 15.1 1 9.6 0.1 7.9 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 RLN20548.1 - 8.7e-07 29.2 6.4 0.026 14.9 0.1 4.8 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN20548.1 - 2.4e-06 27.3 3.9 0.4 11.4 0.1 6.4 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.6 RLN20548.1 - 1e-05 25.2 14.7 0.026 14.3 0.3 5.5 4 2 0 4 4 4 2 Leucine rich repeat HA PF03457.14 RLN20549.1 - 3.6e-26 91.3 0.4 7.4e-06 26.2 0.0 4.8 5 0 0 5 5 5 4 Helicase associated domain Adhes-Ig_like PF09085.10 RLN20549.1 - 0.0069 16.5 0.1 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 Adhesion molecule, immunoglobulin-like Med26 PF08711.11 RLN20549.1 - 0.1 12.7 0.0 8.6 6.5 0.0 2.8 3 0 0 3 3 3 0 TFIIS helical bundle-like domain DUF4560 PF15118.6 RLN20551.1 - 0.086 12.7 0.2 6.2 6.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4560) CENP-H PF05837.12 RLN20551.1 - 1.7 9.1 13.1 3.2 8.2 13.1 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Asp-B-Hydro_N PF05279.11 RLN20551.1 - 1.9 8.5 12.8 5.1 7.1 12.8 1.6 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Thiolase_N PF00108.23 RLN20552.1 - 7e-82 274.7 3.7 1.1e-81 274.1 3.7 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RLN20552.1 - 5.3e-49 164.9 0.1 1.2e-48 163.8 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 RLN20552.1 - 0.036 14.2 0.7 0.19 11.9 0.0 2.6 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 RLN20552.1 - 0.083 12.5 2.5 0.23 11.0 0.7 2.3 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 RLN20552.1 - 0.26 11.2 2.9 15 5.5 0.7 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Peptidase_M24 PF00557.24 RLN20553.1 - 1.3e-52 178.5 0.2 2e-52 177.9 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 RLN20553.1 - 7.2e-28 96.8 0.2 4.8e-27 94.1 0.1 2.2 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Cupin_8 PF13621.6 RLN20554.1 - 7.4e-21 75.0 0.0 2e-18 67.0 0.0 2.5 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 RLN20554.1 - 3.1e-13 50.1 0.0 7.8e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase DnaJ PF00226.31 RLN20554.1 - 1.3e-11 44.4 0.5 3.9e-11 42.9 0.5 1.9 1 1 0 1 1 1 1 DnaJ domain Tad PF13400.6 RLN20554.1 - 0.015 15.6 0.2 3.5 8.0 0.0 2.9 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Leader_Trp PF08255.11 RLN20554.1 - 0.14 12.2 1.0 0.76 9.9 0.2 2.7 2 0 0 2 2 2 0 Trp-operon Leader Peptide UCH PF00443.29 RLN20555.1 - 1.5e-41 142.6 0.0 1.9e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN20555.1 - 0.0004 20.1 0.2 0.29 10.7 0.1 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase hnRNP_Q_AcD PF18360.1 RLN20556.1 - 8.7e-24 83.3 0.0 3.2e-09 36.6 0.0 3.3 3 0 0 3 3 3 3 Heterogeneous nuclear ribonucleoprotein Q acidic domain EF-hand_7 PF13499.6 RLN20557.1 - 0.0011 19.4 1.3 0.63 10.5 0.0 3.4 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN20557.1 - 0.0064 16.3 7.3 1.3 9.2 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 RLN20557.1 - 0.73 9.5 2.9 1.2 8.8 0.0 2.8 3 0 0 3 3 3 0 EF hand Cupin_8 PF13621.6 RLN20558.1 - 1.5 8.5 4.5 3.7 7.2 4.5 1.6 1 0 0 1 1 1 0 Cupin-like domain GREB1 PF15782.5 RLN20558.1 - 2.2 5.3 16.6 3.5 4.6 16.6 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MCD PF05292.11 RLN20558.1 - 5.5 6.5 7.9 11 5.5 6.0 2.3 2 1 0 2 2 2 0 Malonyl-CoA decarboxylase C-terminal domain PPTA PF01239.22 RLN20559.1 - 1.2e-39 132.9 15.1 2.2e-09 36.7 0.2 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat NatB_MDM20 PF09797.9 RLN20559.1 - 0.031 13.2 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit Adaptin_N PF01602.20 RLN20560.1 - 1.6e-104 350.4 8.6 1.2e-54 185.8 1.7 3.0 2 1 1 3 3 3 3 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 RLN20560.1 - 4e-17 62.5 0.0 1.1e-16 61.1 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 RLN20560.1 - 2.1e-05 24.6 8.4 0.013 15.5 0.4 3.5 3 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 RLN20560.1 - 0.014 15.2 0.0 0.064 13.0 0.0 2.2 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis HEAT PF02985.22 RLN20560.1 - 0.057 13.7 0.9 4.3 7.9 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat Vac14_Fab1_bd PF12755.7 RLN20560.1 - 0.17 12.5 0.9 4.3 8.0 0.0 3.4 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region Nipped-B_C PF12830.7 RLN20560.1 - 0.2 11.6 4.5 1.2 9.1 0.0 3.7 5 0 0 5 5 5 0 Sister chromatid cohesion C-terminus HEAT_2 PF13646.6 RLN20560.1 - 2.7 8.4 7.7 1 9.8 0.2 3.8 4 1 0 4 4 4 0 HEAT repeats Acyl-CoA_dh_1 PF00441.24 RLN20561.1 - 5.5e-23 81.8 0.2 9.5e-23 81.1 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RLN20561.1 - 1.7e-12 48.0 0.0 3.9e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 RLN20561.1 - 9.6e-11 41.7 0.0 1.6e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RLN20561.1 - 0.0007 19.9 0.1 0.0018 18.5 0.1 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HisKA_4TM PF16926.5 RLN20562.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal 4TM region of histidine kinase Na_Pi_cotrans PF02690.15 RLN20563.1 - 3e-15 56.5 15.8 2e-14 53.9 15.8 2.0 1 1 0 1 1 1 1 Na+/Pi-cotransporter DUF4381 PF14316.6 RLN20563.1 - 0.0043 17.3 0.7 0.0043 17.3 0.7 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4381) FxsA PF04186.13 RLN20563.1 - 0.031 14.4 1.3 0.031 14.4 1.3 3.1 1 1 2 3 3 3 0 FxsA cytoplasmic membrane protein MLANA PF14991.6 RLN20563.1 - 0.032 14.5 0.8 0.048 14.0 0.2 1.5 1 1 0 1 1 1 0 Protein melan-A FA_desaturase PF00487.24 RLN20563.1 - 0.85 9.4 7.7 1.3 8.8 7.7 1.3 1 0 0 1 1 1 0 Fatty acid desaturase Bax1-I PF01027.20 RLN20563.1 - 1.6 8.5 23.8 0.14 12.0 17.9 1.9 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 GrpE PF01025.19 RLN20564.1 - 1.6e-44 151.5 6.7 1.9e-44 151.3 6.7 1.1 1 0 0 1 1 1 1 GrpE TssR PF17643.1 RLN20564.1 - 0.035 12.1 0.6 0.044 11.7 0.6 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssR EF-hand_7 PF13499.6 RLN20564.1 - 0.11 13.0 0.1 0.28 11.7 0.1 1.9 1 1 0 1 1 1 0 EF-hand domain pair DUF4140 PF13600.6 RLN20564.1 - 0.17 12.4 5.3 0.37 11.3 3.0 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF5090 PF17009.5 RLN20565.1 - 0.11 12.4 1.4 0.18 11.7 1.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5090) PUMA PF15826.5 RLN20581.1 - 0.043 14.0 0.3 0.07 13.3 0.3 1.3 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis Herpes_US9 PF06072.11 RLN20581.1 - 0.13 12.1 0.0 4 7.4 0.0 2.4 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 DUF433 PF04255.14 RLN20581.1 - 0.21 11.5 0.7 2.8 7.9 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF433) JAB PF01398.21 RLN20582.1 - 3.1e-21 75.5 0.1 4.4e-21 75.0 0.1 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 RLN20582.1 - 4.1e-16 59.4 0.0 9.7e-16 58.2 0.0 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function EF-hand_5 PF13202.6 RLN20583.1 - 3e-21 73.9 1.9 3.7e-06 26.2 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_1 PF00036.32 RLN20583.1 - 7.5e-20 68.9 1.2 5.8e-06 25.5 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 RLN20583.1 - 1.2e-18 67.4 1.4 4.9e-12 46.1 0.4 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 RLN20583.1 - 3.7e-16 58.7 0.8 6.9e-10 38.6 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN20583.1 - 6.8e-16 56.8 2.7 6.7e-05 22.5 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain Dockerin_1 PF00404.18 RLN20583.1 - 0.0045 17.2 0.0 1.7 8.9 0.0 2.7 2 0 0 2 2 2 1 Dockerin type I domain SPARC_Ca_bdg PF10591.9 RLN20583.1 - 0.025 14.9 0.0 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 RLN20583.1 - 0.04 13.8 0.0 1.7 8.6 0.0 2.5 2 1 1 3 3 3 0 Caleosin related protein MFS_1_like PF12832.7 RLN20584.1 - 1.2e-62 212.0 26.1 2.2e-62 211.2 26.1 1.4 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RLN20584.1 - 3.1e-25 88.8 49.4 6.5e-20 71.4 27.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 RLN20584.1 - 2.1e-19 69.8 20.1 2.9e-19 69.3 20.1 1.2 1 0 0 1 1 1 1 Nucleoside H+ symporter MFS_2 PF13347.6 RLN20584.1 - 6.1e-12 44.8 19.5 2.3e-07 29.7 8.1 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein LacY_symp PF01306.19 RLN20584.1 - 4.2e-08 32.4 19.9 6.6e-08 31.7 19.9 1.3 1 0 0 1 1 1 1 LacY proton/sugar symporter MFS_1_like PF12832.7 RLN20585.1 - 8.8e-63 212.5 23.0 1.5e-62 211.6 23.0 1.4 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RLN20585.1 - 6.1e-21 74.7 34.5 6.1e-12 45.1 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 RLN20585.1 - 1.5e-15 57.1 21.1 2e-15 56.7 21.1 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter MFS_2 PF13347.6 RLN20585.1 - 1.5e-09 37.0 23.5 6.3e-08 31.6 11.0 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein LacY_symp PF01306.19 RLN20585.1 - 1.3e-06 27.4 22.5 2.9e-06 26.3 22.5 1.5 1 1 0 1 1 1 1 LacY proton/sugar symporter MFS_3 PF05977.13 RLN20585.1 - 3.5e-05 22.4 13.3 0.00063 18.3 5.7 2.1 1 1 1 2 2 2 2 Transmembrane secretion effector UNC-93 PF05978.16 RLN20585.1 - 0.0015 18.2 1.2 0.0015 18.2 1.2 2.8 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 VMA21 PF09446.10 RLN20585.1 - 0.0019 18.3 2.7 7.3 6.8 0.2 4.4 3 0 0 3 3 3 1 VMA21-like domain GBP PF02263.19 RLN20586.1 - 2.9e-13 49.7 5.1 4.5e-13 49.1 0.0 3.2 3 1 0 3 3 3 1 Guanylate-binding protein, N-terminal domain Cauli_AT PF03233.13 RLN20586.1 - 2.4 8.1 14.9 0.97 9.3 9.1 3.1 1 1 1 2 2 2 0 Aphid transmission protein HEPN_DZIP3 PF18738.1 RLN20587.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 DZIP3/ hRUL138-like HEPN SWIM PF04434.17 RLN20588.1 - 8.3e-05 22.2 0.1 0.00016 21.3 0.1 1.4 1 0 0 1 1 1 1 SWIM zinc finger DUF1242 PF06842.12 RLN20588.1 - 0.22 11.4 3.9 0.12 12.2 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1242) ADH_zinc_N_2 PF13602.6 RLN20600.1 - 5.2e-10 40.5 0.0 5.8e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_1 PF00232.18 RLN20601.1 - 2.4e-50 171.3 0.1 2.8e-50 171.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Sugar_tr PF00083.24 RLN20602.1 - 1.5e-74 251.5 23.9 5e-53 180.6 6.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RLN20602.1 - 5.9e-22 78.1 29.1 5.2e-12 45.4 8.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1388 PF07142.12 RLN20602.1 - 0.14 12.1 0.7 0.21 11.6 0.7 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) HisK_N PF09385.10 RLN20602.1 - 0.22 11.5 0.2 0.37 10.8 0.2 1.3 1 0 0 1 1 1 0 Histidine kinase N terminal Calreticulin PF00262.18 RLN20603.1 - 7e-27 94.2 0.0 7.8e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Calreticulin family Pyr_redox_2 PF07992.14 RLN20604.1 - 1.4e-70 237.9 6.7 1.4e-70 237.9 6.7 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 RLN20604.1 - 1.4e-36 125.1 0.2 3.7e-36 123.7 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 RLN20604.1 - 1.9e-21 76.4 4.9 3.3e-17 62.8 0.2 3.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 RLN20604.1 - 4.1e-11 42.6 7.8 1.1e-10 41.2 1.1 2.5 2 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 RLN20604.1 - 8.6e-10 38.4 4.1 1.3e-06 28.0 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RLN20604.1 - 1.1e-09 38.2 4.5 1.1e-09 38.2 4.5 3.0 2 2 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 RLN20604.1 - 3.4e-09 36.3 17.8 1.3e-06 27.7 2.2 4.4 3 1 2 5 5 5 2 FAD binding domain NAD_binding_8 PF13450.6 RLN20604.1 - 1.6e-07 31.5 6.3 0.00015 21.9 0.4 3.3 2 1 0 3 3 3 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 RLN20604.1 - 5.8e-07 28.6 11.5 0.00045 19.0 1.5 4.1 4 0 0 4 4 4 2 HI0933-like protein FAD_binding_3 PF01494.19 RLN20604.1 - 2.2e-06 27.1 14.2 0.027 13.7 1.0 3.5 3 1 1 4 4 4 3 FAD binding domain AlaDh_PNT_C PF01262.21 RLN20604.1 - 3.2e-06 26.6 4.5 0.0036 16.6 0.4 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 RLN20604.1 - 1.4e-05 24.5 0.6 0.0011 18.2 0.0 2.4 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 RLN20604.1 - 0.00015 21.1 1.3 0.057 12.6 0.1 2.6 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) XdhC_C PF13478.6 RLN20604.1 - 0.0069 16.9 0.1 1.1 9.7 0.0 2.6 2 0 0 2 2 2 1 XdhC Rossmann domain NAD_binding_7 PF13241.6 RLN20604.1 - 0.012 16.0 2.9 3.7 8.0 0.1 3.5 3 0 0 3 3 3 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 RLN20604.1 - 0.014 14.4 5.2 0.11 11.5 0.1 3.1 2 2 1 3 3 3 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 RLN20604.1 - 0.03 13.7 0.1 0.51 9.7 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 RLN20604.1 - 0.1 12.4 0.1 0.1 12.4 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 RLN20604.1 - 0.17 11.4 21.1 0.65 9.5 0.1 4.2 2 2 1 4 4 4 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 RLN20604.1 - 0.85 9.2 4.1 0.52 9.9 0.1 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.14 RLN20604.1 - 1 8.1 3.0 1.8 7.3 0.8 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Npa1 PF11707.8 RLN20630.1 - 1.4e-25 90.4 1.9 2.8e-25 89.4 0.0 2.3 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal Ferric_reduct PF01794.19 RLN20631.1 - 2.3e-18 66.5 10.1 2.3e-18 66.5 10.1 2.7 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 RLN20631.1 - 1.8e-12 47.3 0.0 5.2e-12 45.8 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 RLN20631.1 - 3.6e-11 43.4 0.0 5.5e-10 39.6 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain His_Phos_2 PF00328.22 RLN20632.1 - 1e-13 51.4 0.1 1.5e-13 50.9 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) CDO_I PF05995.12 RLN20633.1 - 1.9e-28 98.9 0.0 2.7e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 RLN20633.1 - 0.0012 18.3 0.1 0.0032 17.0 0.1 1.8 1 1 0 1 1 1 1 PCO_ADO Syja_N PF02383.18 RLN20633.1 - 0.037 13.3 0.0 0.04 13.2 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain PDEase_I PF00233.19 RLN20634.1 - 7.9e-60 202.5 0.0 1.6e-59 201.5 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Pur_ac_phosph_N PF16656.5 RLN20635.1 - 2.2e-18 66.6 0.0 4.8e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain DnaJ PF00226.31 RLN20635.1 - 1.4e-15 57.2 0.5 3.1e-15 56.0 0.5 1.6 1 1 0 1 1 1 1 DnaJ domain Metallophos PF00149.28 RLN20635.1 - 2e-13 51.3 1.6 4.8e-13 50.1 1.6 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 RLN20635.1 - 4.3e-11 43.5 0.3 4.3e-11 43.5 0.3 2.2 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Asp_Glu_race PF01177.22 RLN20637.1 - 1.6e-23 83.8 0.0 3.7e-23 82.5 0.0 1.6 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase DUF3336 PF11815.8 RLN20638.1 - 1.5e-21 76.5 0.1 2.6e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 RLN20638.1 - 2.2e-16 60.7 0.0 3.8e-15 56.6 0.0 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase PX PF00787.24 RLN20640.1 - 1e-09 38.4 0.0 1.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 PX domain ETAA1 PF15350.6 RLN20640.1 - 0.044 12.1 0.2 0.059 11.7 0.2 1.0 1 0 0 1 1 1 0 Ewing's tumour-associated antigen 1 homologue Mito_carr PF00153.27 RLN20641.1 - 6e-51 170.3 1.1 6.3e-17 61.3 0.4 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein SAP30_Sin3_bdg PF13867.6 RLN20642.1 - 6.1e-14 52.1 0.1 1e-13 51.4 0.1 1.4 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 PHD PF00628.29 RLN20642.1 - 4.8e-06 26.4 5.7 1.3e-05 25.0 5.7 1.8 1 0 0 1 1 1 1 PHD-finger Pol_alpha_B_N PF08418.10 RLN20642.1 - 0.28 11.1 5.3 0.53 10.2 5.3 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Macoilin PF09726.9 RLN20642.1 - 1 7.9 9.8 1.1 7.7 9.8 1.1 1 0 0 1 1 1 0 Macoilin family Ion_trans_2 PF07885.16 RLN20643.1 - 2.7e-14 52.9 3.8 6.4e-14 51.7 3.8 1.6 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 RLN20643.1 - 1.2e-11 44.3 10.9 2e-11 43.6 10.9 1.3 1 0 0 1 1 1 1 Ion transport protein BK_channel_a PF03493.18 RLN20643.1 - 1.4e-10 41.2 0.0 5.2e-09 36.2 0.0 2.7 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit WD40 PF00400.32 RLN20645.1 - 2.2e-20 72.6 1.8 0.021 15.7 0.0 7.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN20645.1 - 2.3e-05 24.6 0.0 0.03 14.6 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 RLN20645.1 - 0.004 16.8 0.0 0.0085 15.7 0.0 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain LisH PF08513.11 RLN20645.1 - 0.025 14.6 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 LisH PALB2_WD40 PF16756.5 RLN20645.1 - 0.11 11.4 0.3 0.43 9.5 0.1 1.8 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Zip PF02535.22 RLN20646.1 - 8.2e-50 169.9 11.0 9.3e-50 169.7 11.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2070 PF09843.9 RLN20646.1 - 0.21 9.8 8.5 0.36 9.0 8.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) NmrA PF05368.13 RLN20647.1 - 2.8e-12 46.7 0.1 4.2e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 RLN20647.1 - 0.00012 22.0 0.6 0.17 11.8 1.1 3.1 2 1 0 2 2 2 1 NAD(P)H-binding ApbA PF02558.16 RLN20647.1 - 0.00021 21.0 0.6 0.00042 20.0 0.6 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 RLN20647.1 - 0.00046 20.4 0.1 0.0014 18.9 0.1 1.9 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 RLN20647.1 - 0.0019 17.5 0.6 0.003 16.9 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain UDPG_MGDP_dh_N PF03721.14 RLN20647.1 - 0.0074 15.9 0.1 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 RLN20647.1 - 0.0082 16.4 0.5 0.018 15.3 0.2 1.7 2 0 0 2 2 1 1 TrkA-N domain Shikimate_DH PF01488.20 RLN20647.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.6 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 RLN20647.1 - 0.015 15.8 0.0 0.051 14.1 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 RLN20647.1 - 0.018 15.5 0.0 0.044 14.2 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 RLN20647.1 - 0.049 12.9 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RLN20647.1 - 0.059 12.6 0.0 0.096 11.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RLN20647.1 - 0.061 12.9 1.0 0.12 11.9 1.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase PglD_N PF17836.1 RLN20647.1 - 0.12 13.1 0.1 0.28 11.8 0.1 1.7 1 0 0 1 1 1 0 PglD N-terminal domain adh_short PF00106.25 RLN20647.1 - 0.18 11.2 0.3 0.36 10.2 0.3 1.4 1 0 0 1 1 1 0 short chain dehydrogenase RRM_1 PF00076.22 RLN20648.1 - 9.5e-55 182.3 0.0 8.7e-20 70.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN20648.1 - 4.5e-08 33.1 0.0 0.21 11.7 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif OB_RNB PF08206.11 RLN20648.1 - 0.087 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain Nup35_RRM_2 PF14605.6 RLN20648.1 - 0.12 12.4 0.1 3.5 7.7 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif HECT PF00632.25 RLN20661.1 - 4e-66 223.6 0.0 5.1e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zinc_ribbon_15 PF17032.5 RLN20661.1 - 0.11 13.3 0.2 0.22 12.3 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon family DZR PF12773.7 RLN20661.1 - 0.15 12.1 0.3 0.3 11.1 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon HECT PF00632.25 RLN20662.1 - 1.3e-66 225.2 0.0 2.4e-66 224.3 0.0 1.4 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DZR PF12773.7 RLN20662.1 - 0.041 13.9 0.5 0.084 12.9 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 RLN20662.1 - 0.32 10.8 3.1 0.67 9.8 3.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 RLN20662.1 - 1.4 8.5 7.4 4.1 7.0 0.1 4.0 5 0 0 5 5 5 0 TFIIB zinc-binding FANCF PF11107.8 RLN20663.1 - 2.7e-06 26.8 2.4 3.5e-06 26.5 2.4 1.1 1 0 0 1 1 1 1 Fanconi anemia group F protein (FANCF) CCDC53 PF10152.9 RLN20664.1 - 0.0091 16.4 3.5 0.099 13.1 0.0 3.1 3 0 0 3 3 3 1 Subunit CCDC53 of WASH complex WH2 PF02205.20 RLN20664.1 - 0.19 11.6 3.6 20 5.2 0.1 3.7 4 0 0 4 4 4 0 WH2 motif DUF2802 PF10975.8 RLN20664.1 - 0.31 11.2 3.9 6.9 6.9 0.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) CCDC53 PF10152.9 RLN20665.1 - 0.0075 16.7 3.2 0.099 13.1 0.0 3.1 3 0 0 3 3 3 1 Subunit CCDC53 of WASH complex WH2 PF02205.20 RLN20665.1 - 0.19 11.6 3.6 20 5.2 0.1 3.7 4 0 0 4 4 4 0 WH2 motif DUF2802 PF10975.8 RLN20665.1 - 0.33 11.1 3.9 6.9 6.9 0.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) Flavodoxin_1 PF00258.25 RLN20666.1 - 6.5e-27 94.5 0.0 9.6e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 RLN20666.1 - 8.4e-20 71.3 0.0 1.7e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 RLN20666.1 - 4.3e-06 27.3 0.0 1.8e-05 25.3 0.0 1.9 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain Aldedh PF00171.22 RLN20667.1 - 2.9e-144 481.0 1.0 3.4e-144 480.8 1.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 RLN20667.1 - 1.2e-05 24.9 0.0 0.0025 17.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) IF4E PF01652.18 RLN20667.1 - 0.17 11.6 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic initiation factor 4E XendoU PF09412.10 RLN20668.1 - 1.1e-35 123.2 0.0 1.6e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease XendoU IQ PF00612.27 RLN20668.1 - 0.044 13.6 1.2 0.11 12.3 1.2 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif XendoU PF09412.10 RLN20669.1 - 1.8e-44 152.0 0.0 2.3e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU HECT PF00632.25 RLN20670.1 - 1.5e-67 228.3 0.0 4e-67 226.9 0.0 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Actin PF00022.19 RLN20671.1 - 8.6e-17 60.8 0.0 1e-16 60.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 RLN20671.1 - 0.038 12.8 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 MreB/Mbl protein PQQ_3 PF13570.6 RLN20671.1 - 0.052 14.0 0.4 0.94 10.1 0.0 2.5 2 1 0 2 2 2 0 PQQ-like domain DUF995 PF06191.12 RLN20671.1 - 0.18 11.5 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF995) Laminin_G_3 PF13385.6 RLN20701.1 - 4.2e-06 27.0 0.3 9.9e-06 25.8 0.3 1.6 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily ABC2_membrane PF01061.24 RLN20702.1 - 5.8e-30 104.3 27.0 7.4e-30 103.9 27.0 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN20702.1 - 6.1e-15 55.9 0.1 1.3e-14 54.9 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 RLN20702.1 - 0.048 13.9 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_trans_N PF14510.6 RLN20702.1 - 0.069 13.8 0.2 0.17 12.5 0.0 1.7 2 0 0 2 2 2 0 ABC-transporter N-terminal AAA_29 PF13555.6 RLN20702.1 - 0.12 12.1 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN20702.1 - 0.17 11.4 0.1 0.31 10.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 RLN20702.1 - 0.18 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC2_membrane PF01061.24 RLN20703.1 - 7.2e-30 104.0 27.0 9.4e-30 103.6 27.0 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN20703.1 - 7.5e-15 55.6 0.1 1.6e-14 54.5 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 RLN20703.1 - 0.058 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_trans_N PF14510.6 RLN20703.1 - 0.065 13.9 0.0 0.18 12.4 0.0 1.8 1 0 0 1 1 1 0 ABC-transporter N-terminal AAA_29 PF13555.6 RLN20703.1 - 0.15 11.9 0.1 0.34 10.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN20703.1 - 0.2 11.2 0.1 0.36 10.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 RLN20703.1 - 0.55 9.3 16.8 1.2 8.2 16.8 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein ABC_membrane PF00664.23 RLN20705.1 - 1.8e-58 198.4 30.4 2.4e-35 122.5 7.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN20705.1 - 2.9e-49 167.1 0.0 1.3e-28 100.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN20705.1 - 8.3e-09 35.2 0.3 0.0019 17.7 0.0 4.1 2 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RLN20705.1 - 2.2e-06 27.7 0.2 0.091 12.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 RLN20705.1 - 0.00038 20.6 0.1 0.026 14.6 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 RLN20705.1 - 0.00046 19.9 1.5 0.6 9.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN20705.1 - 0.00059 19.8 2.4 0.3 11.0 0.2 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_21 PF13304.6 RLN20705.1 - 0.0007 19.5 1.5 4.8 6.9 0.0 3.6 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system DEAD PF00270.29 RLN20705.1 - 0.00085 19.1 0.0 0.003 17.3 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.6 RLN20705.1 - 0.0015 18.9 0.1 0.68 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 RLN20705.1 - 0.011 15.9 0.1 5.4 7.3 0.0 3.4 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 RLN20705.1 - 0.014 14.9 0.1 0.27 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 RLN20705.1 - 0.028 14.9 0.3 1.2 9.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 RLN20705.1 - 0.036 14.2 0.0 2.3 8.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 RLN20705.1 - 0.049 13.9 0.0 12 6.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 RLN20705.1 - 0.059 12.7 0.5 0.84 8.9 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.13 RLN20705.1 - 0.065 12.4 0.6 9.1 5.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 RLN20705.1 - 0.07 12.8 0.2 0.86 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 RLN20705.1 - 0.081 12.7 1.1 5.4 6.7 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_7 PF12775.7 RLN20705.1 - 0.14 11.7 0.9 8.7 5.8 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 RLN20705.1 - 0.15 11.6 0.6 2 8.0 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 RLN20705.1 - 0.23 11.5 3.5 0.26 11.4 0.1 2.4 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_22 PF13401.6 RLN20705.1 - 0.37 11.1 3.1 26 5.1 0.2 3.1 3 0 0 3 3 3 0 AAA domain Glyco_hydro_3 PF00933.21 RLN20710.1 - 5.9e-53 180.3 0.0 7.6e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN20710.1 - 3.9e-07 30.2 0.0 7.3e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain ATG16 PF08614.11 RLN20711.1 - 1.6e-05 25.2 17.9 1.6e-05 25.2 17.9 11.5 5 1 4 10 10 10 3 Autophagy protein 16 (ATG16) WD40 PF00400.32 RLN20712.1 - 2.1e-46 155.0 26.9 1.8e-05 25.4 0.1 11.5 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN20712.1 - 1.9e-20 72.9 2.7 0.019 15.3 0.0 8.1 5 3 2 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 RLN20712.1 - 1.3e-14 54.4 3.2 2.2e-14 53.7 3.2 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 RLN20712.1 - 0.00011 21.2 6.9 2.2 7.2 0.0 6.5 5 1 1 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 RLN20712.1 - 0.0013 18.2 0.0 0.25 10.6 0.0 3.8 5 1 0 6 6 6 1 WD40-like domain SDA1 PF05285.12 RLN20712.1 - 0.011 15.2 22.0 0.025 14.0 12.8 2.2 2 0 0 2 2 2 0 SDA1 Nup160 PF11715.8 RLN20712.1 - 0.013 14.1 3.3 1.1 7.8 0.0 3.3 3 1 0 3 3 3 0 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 RLN20712.1 - 0.038 13.3 0.0 16 4.6 0.0 3.4 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PHTB1_N PF14727.6 RLN20712.1 - 0.17 11.2 0.1 2.9 7.2 0.0 2.6 2 0 0 2 2 2 0 PTHB1 N-terminus DUF2956 PF11169.8 RLN20712.1 - 1 9.6 17.2 3.7 7.8 3.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) CSRNP_N PF16019.5 RLN20712.1 - 1.2 9.0 6.3 3.2 7.6 1.4 2.4 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus AIF_C PF14721.6 RLN20712.1 - 1.7 9.0 13.1 7.8 6.9 2.9 2.6 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term XRN_M PF17846.1 RLN20712.1 - 9.4 5.1 11.5 1 8.3 1.0 2.4 2 0 0 2 2 2 0 Xrn1 helical domain RhoGAP PF00620.27 RLN20719.1 - 4.3e-16 59.1 0.0 1.4e-15 57.4 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain Exo_endo_phos PF03372.23 RLN20719.1 - 2.1e-09 37.2 0.0 3.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Vps5 PF09325.10 RLN20720.1 - 1.8e-33 116.0 0.2 2.7e-33 115.5 0.2 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 RLN20720.1 - 5.3e-30 103.7 0.1 9.4e-30 102.9 0.1 1.4 1 0 0 1 1 1 1 PX domain BAR PF03114.18 RLN20720.1 - 0.00016 21.4 0.6 0.00026 20.7 0.6 1.3 1 0 0 1 1 1 1 BAR domain BAR_3_WASP_bdg PF10456.9 RLN20720.1 - 0.0019 17.7 1.1 0.013 15.0 1.1 2.1 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein FAM92 PF06730.11 RLN20720.1 - 0.038 13.4 0.2 0.059 12.8 0.2 1.3 1 0 0 1 1 1 0 FAM92 protein Peptidase_C1 PF00112.23 RLN20721.1 - 3.9e-54 184.0 0.1 5.3e-54 183.6 0.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RLN20721.1 - 0.00035 19.5 0.4 0.059 12.1 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Inhibitor_I29 PF08246.12 RLN20721.1 - 0.062 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) DUF4038 PF13204.6 RLN20730.1 - 7.4e-90 301.7 2.0 8.9e-90 301.4 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Collagen_bind_2 PF12904.7 RLN20730.1 - 3.5e-11 42.9 0.0 7.2e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Putative collagen-binding domain of a collagenase DPBB_1 PF03330.18 RLN20731.1 - 1.9e-07 31.2 1.3 2e-06 28.0 1.3 2.7 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 RLN20731.1 - 0.00046 20.0 1.3 0.0015 18.4 1.3 2.0 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 RLN20732.1 - 3.7e-06 27.1 0.4 3.7e-06 27.1 0.4 2.3 2 1 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 RLN20732.1 - 0.0013 18.6 0.9 0.0031 17.4 0.9 1.7 1 0 0 1 1 1 1 Barwin family SOG2 PF10428.9 RLN20732.1 - 1.7 7.8 22.6 2.2 7.4 22.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Rotamase_3 PF13616.6 RLN20735.1 - 7.6e-37 126.4 0.1 6e-17 62.3 0.0 2.2 2 0 0 2 2 2 2 PPIC-type PPIASE domain Rotamase PF00639.21 RLN20735.1 - 7.2e-35 119.8 0.2 1.7e-16 60.9 0.0 2.2 2 0 0 2 2 2 2 PPIC-type PPIASE domain Rotamase_2 PF13145.6 RLN20735.1 - 5e-13 50.0 0.0 3e-05 24.8 0.0 2.3 2 1 0 2 2 2 2 PPIC-type PPIASE domain SMC_hinge PF06470.13 RLN20735.1 - 1.4e-05 25.4 0.1 0.024 14.9 0.1 2.1 2 0 0 2 2 2 2 SMC proteins Flexible Hinge Domain DUF3107 PF11305.8 RLN20735.1 - 0.4 11.0 3.0 7 7.0 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3107) Rotamase_3 PF13616.6 RLN20736.1 - 1.3e-09 38.6 0.0 3.1e-08 34.2 0.0 2.1 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase PF00639.21 RLN20736.1 - 5.6e-09 36.8 0.1 1e-07 32.8 0.0 2.3 1 1 1 2 2 2 1 PPIC-type PPIASE domain Phage_TAC_7 PF10109.9 RLN20736.1 - 0.07 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone proteins, E, or 41 or 14 TPPK_C PF12555.8 RLN20736.1 - 0.21 11.7 3.7 0.41 10.7 3.7 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal HTH_Tnp_Tc5 PF03221.16 RLN20737.1 - 7.9e-09 35.4 0.5 1.4e-08 34.6 0.5 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain MSA-2c PF12238.8 RLN20737.1 - 4.3 7.3 6.4 4.3 7.3 3.1 2.1 1 1 1 2 2 2 0 Merozoite surface antigen 2c DPBB_1 PF03330.18 RLN20738.1 - 1.5e-06 28.4 0.1 8.4e-06 26.0 0.1 2.2 2 0 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 RLN20738.1 - 0.0032 17.3 0.8 0.0053 16.6 0.8 1.4 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 RLN20739.1 - 6e-08 32.9 3.3 4.1e-07 30.2 3.3 2.3 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 RLN20739.1 - 0.00063 19.6 2.3 0.0011 18.8 2.3 1.4 1 0 0 1 1 1 1 Barwin family GPI-anchored PF10342.9 RLN20739.1 - 0.019 15.7 2.4 0.028 15.2 0.5 2.2 2 1 1 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family HTH_Tnp_Tc5 PF03221.16 RLN20740.1 - 1.1e-07 31.7 0.0 3.1e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_7 PF02796.15 RLN20740.1 - 0.033 14.2 0.0 0.087 12.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DDE_3 PF13358.6 RLN20740.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_32 PF13565.6 RLN20740.1 - 0.14 12.8 0.0 4 8.1 0.0 3.0 3 0 0 3 3 3 0 Homeodomain-like domain DSPn PF14671.6 RLN20741.1 - 0.07 13.6 0.0 0.098 13.1 0.0 1.1 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half Phage_holin_2_4 PF16082.5 RLN20742.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DPBB_1 PF03330.18 RLN20744.1 - 7.5e-06 26.1 0.1 3.1e-05 24.2 0.1 2.1 1 0 0 1 1 1 1 Lytic transglycolase TMEM154 PF15102.6 RLN20744.1 - 0.0015 18.5 1.7 0.0015 18.5 1.7 4.4 1 1 3 4 4 4 1 TMEM154 protein family Barwin PF00967.17 RLN20744.1 - 0.021 14.7 0.9 0.044 13.6 0.9 1.6 1 0 0 1 1 1 0 Barwin family LGT PF01790.18 RLN20744.1 - 0.073 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase DUF5305 PF17231.2 RLN20744.1 - 0.094 12.1 1.7 0.096 12.1 0.3 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Hamartin PF04388.12 RLN20744.1 - 3.7 6.1 34.3 6.7 5.2 34.3 1.4 1 0 0 1 1 1 0 Hamartin protein Gram_pos_anchor PF00746.21 RLN20744.1 - 3.9 7.5 7.1 0.77 9.8 0.4 2.5 2 0 0 2 2 2 0 LPXTG cell wall anchor motif MYEOV2 PF15004.6 RLN20746.1 - 0.049 14.1 0.0 0.15 12.5 0.1 1.8 2 0 0 2 2 2 0 Myeloma-overexpressed-like Mid2 PF04478.12 RLN20747.1 - 0.041 13.7 0.1 0.074 12.9 0.1 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM51 PF15345.6 RLN20747.1 - 0.047 13.5 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Nop52 PF05997.12 RLN20749.1 - 5.7e-44 150.5 0.0 5.7e-44 150.5 0.0 2.4 2 1 0 2 2 2 1 Nucleolar protein,Nop52 PH PF00169.29 RLN20750.1 - 3.7e-18 66.0 0.0 1.6e-07 31.8 0.0 2.5 2 0 0 2 2 2 2 PH domain RabGAP-TBC PF00566.18 RLN20750.1 - 1.3e-08 34.8 0.0 2.6e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_11 PF15413.6 RLN20750.1 - 0.0091 16.4 0.2 0.75 10.2 0.1 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 RLN20750.1 - 0.02 15.2 0.0 3.6 8.0 0.0 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain PH_8 PF15409.6 RLN20750.1 - 0.27 11.5 0.6 19 5.6 0.0 3.1 3 0 0 3 3 3 0 Pleckstrin homology domain DUF1180 PF06679.12 RLN20751.1 - 0.0098 16.3 0.1 0.014 15.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) DUF1180 PF06679.12 RLN20752.1 - 0.0032 17.9 0.1 0.0057 17.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) RIFIN PF02009.16 RLN20752.1 - 0.032 14.1 0.2 0.044 13.7 0.2 1.1 1 0 0 1 1 1 0 Rifin Orf78 PF06024.12 RLN20752.1 - 0.11 12.8 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) BT1 PF03092.16 RLN20753.1 - 3.9e-09 35.3 17.7 5.9e-09 34.7 4.1 2.9 2 1 1 3 3 3 2 BT1 family DUF3975 PF13126.6 RLN20753.1 - 0.11 13.0 3.4 18 5.9 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3975) Holin_2-3 PF13272.6 RLN20753.1 - 0.35 11.2 4.2 0.12 12.7 0.7 2.1 2 0 0 2 2 2 0 Putative 2/3 transmembrane domain holin BT1 PF03092.16 RLN20754.1 - 3.5e-11 42.1 7.3 3.5e-11 42.1 7.3 2.4 2 1 1 3 3 3 1 BT1 family ETM PF17577.2 RLN20754.1 - 0.07 13.7 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 ECORI-T site Rhodanese PF00581.20 RLN20758.1 - 3.4e-28 98.3 0.0 2.8e-13 50.3 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain CAF1 PF04857.20 RLN20761.1 - 1.4e-19 70.5 4.3 5.9e-11 42.1 0.0 2.8 2 1 0 2 2 2 2 CAF1 family ribonuclease zf-CCHC PF00098.23 RLN20762.1 - 1.5e-08 34.3 16.3 7e-05 22.7 4.8 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 RLN20762.1 - 0.0057 16.6 9.6 0.11 12.5 2.6 3.0 2 1 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 RLN20762.1 - 0.0075 16.0 14.2 0.013 15.2 1.8 2.8 2 1 1 3 3 3 2 Zinc knuckle zf-CCHC_6 PF15288.6 RLN20762.1 - 0.19 11.6 11.7 1.4 8.8 1.2 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-ribbon_3 PF13248.6 RLN20762.1 - 0.28 10.7 4.0 4.7 6.8 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 RLN20762.1 - 1.1 9.0 3.8 19 5.2 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 RLN20762.1 - 1.9 8.3 5.5 17 5.3 0.3 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain DUF1284 PF06935.11 RLN20762.1 - 9.1 6.8 10.3 2.1 8.8 0.7 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1284) SRPRB PF09439.10 RLN20763.1 - 2.8e-33 114.9 0.0 3.7e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 RLN20763.1 - 4.7e-14 52.2 0.0 7.1e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RLN20763.1 - 2.6e-07 30.9 0.0 4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RLN20763.1 - 4.9e-07 29.5 0.0 7.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 RLN20763.1 - 7.2e-05 22.4 0.0 0.00012 21.7 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_27 PF13514.6 RLN20763.1 - 0.016 14.8 0.3 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 RLN20763.1 - 0.14 11.5 0.0 0.4 10.0 0.0 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Hydantoinase_B PF02538.14 RLN20764.1 - 6.2e-209 694.7 0.2 8.1e-209 694.3 0.2 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 RLN20764.1 - 5.2e-97 324.6 0.0 9.1e-97 323.8 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 RLN20764.1 - 1.7e-58 197.3 0.5 3.6e-56 189.7 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Kinesin PF00225.23 RLN20765.1 - 3.2e-50 171.0 0.0 1.7e-47 162.0 0.0 2.4 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 RLN20765.1 - 1.9e-15 57.1 0.0 3.5e-13 49.7 0.0 3.3 2 1 0 2 2 2 1 Microtubule binding PH PF00169.29 RLN20765.1 - 3.2e-10 40.4 0.0 1.1e-09 38.8 0.0 1.9 1 0 0 1 1 1 1 PH domain Kinesin_assoc PF16183.5 RLN20765.1 - 0.00024 21.3 0.6 0.00024 21.3 0.6 3.6 2 2 1 3 3 3 1 Kinesin-associated SRRM_C PF15230.6 RLN20765.1 - 0.0061 17.1 2.8 0.034 14.7 2.8 2.3 1 0 0 1 1 1 1 Serine/arginine repetitive matrix protein C-terminus FHA PF00498.26 RLN20765.1 - 0.027 14.8 0.0 0.14 12.5 0.0 2.2 2 0 0 2 2 2 0 FHA domain adh_short PF00106.25 RLN20792.1 - 2.1e-38 131.7 0.9 9.5e-21 74.1 0.1 3.2 2 1 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 RLN20792.1 - 2.6e-27 95.9 0.3 2.6e-16 59.9 0.0 3.1 2 1 1 3 3 3 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN20792.1 - 2e-06 27.8 0.1 3.1e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN20792.1 - 0.00032 20.3 0.0 0.00051 19.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 RLN20792.1 - 0.00074 19.5 0.0 0.014 15.3 0.0 2.6 2 1 0 2 2 2 1 NAD(P)H-binding Viral_protease PF08715.10 RLN20792.1 - 0.1 11.9 0.1 3.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Papain like viral protease PP2C PF00481.21 RLN20798.1 - 1.6e-36 126.2 0.0 1e-34 120.4 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.25 RLN20798.1 - 9.2e-28 97.3 0.0 6.2e-27 94.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN20798.1 - 2.1e-08 33.8 0.0 7.9e-08 31.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase SpoIIE PF07228.12 RLN20798.1 - 0.004 17.1 0.2 0.72 9.7 0.1 2.7 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Kinase-like PF14531.6 RLN20798.1 - 0.01 15.2 0.0 3.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 RLN20798.1 - 0.023 14.1 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PP2C_2 PF13672.6 RLN20798.1 - 0.082 12.5 2.9 0.37 10.4 2.9 2.1 1 1 0 1 1 1 0 Protein phosphatase 2C zf-C2HC_2 PF13913.6 RLN20798.1 - 0.22 11.5 1.1 0.53 10.3 1.1 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 RLN20798.1 - 0.25 12.3 5.7 1.5 9.9 3.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 RLN20798.1 - 0.89 9.9 3.8 2.4 8.5 3.8 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 RLN20798.1 - 7.7 7.2 5.8 29 5.4 2.9 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Histone PF00125.24 RLN20810.1 - 9.9e-19 68.0 0.1 1.2e-18 67.8 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 RLN20810.1 - 0.00022 21.7 0.0 0.00036 21.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 RLN20810.1 - 0.0099 16.1 0.1 0.029 14.6 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 RLN20810.1 - 0.068 13.2 0.1 0.077 13.0 0.1 1.2 1 0 0 1 1 1 0 YscO-like protein RSN1_7TM PF02714.15 RLN20812.1 - 8.2e-54 182.8 13.8 8.2e-54 182.8 13.8 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 RLN20812.1 - 1.6e-32 112.4 0.0 8.7e-32 110.0 0.0 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 RLN20812.1 - 3.2e-26 92.6 2.5 2.4e-17 63.7 0.1 2.3 1 1 1 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter DZR PF12773.7 RLN20813.1 - 0.00015 21.7 8.2 0.075 13.1 0.7 2.6 2 1 0 2 2 2 2 Double zinc ribbon zf-NADH-PPase PF09297.11 RLN20813.1 - 0.0019 17.8 8.9 0.43 10.3 0.2 3.7 3 0 0 3 3 3 3 NADH pyrophosphatase zinc ribbon domain NOB1_Zn_bind PF08772.11 RLN20813.1 - 0.053 13.7 1.1 0.053 13.7 1.1 3.1 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like HypA PF01155.19 RLN20813.1 - 0.099 12.7 5.4 1.1 9.4 0.5 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Peptidase_C2 PF00648.21 RLN20813.1 - 0.11 11.5 0.3 0.18 10.8 0.3 1.3 1 0 0 1 1 1 0 Calpain family cysteine protease zinc_ribbon_2 PF13240.6 RLN20813.1 - 0.48 10.2 17.1 1.9 8.3 0.5 3.9 3 1 0 3 3 3 0 zinc-ribbon domain PCI PF01399.27 RLN20815.1 - 0.17 12.4 0.1 0.17 12.4 0.1 3.6 4 0 0 4 4 4 0 PCI domain zf-C4H2 PF10146.9 RLN20815.1 - 1.1 9.5 19.9 12 6.1 17.5 2.7 2 0 0 2 2 2 0 Zinc finger-containing protein Atg14 PF10186.9 RLN20815.1 - 3.1 6.8 17.2 7.3 5.6 17.2 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Borrelia_P83 PF05262.11 RLN20815.1 - 4.6 5.6 20.4 8.5 4.7 20.4 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein PAPA-1 PF04795.12 RLN20816.1 - 0.062 14.1 0.7 0.062 14.1 0.7 3.4 3 0 0 3 3 3 0 PAPA-1-like conserved region DUF2969 PF11184.8 RLN20816.1 - 0.11 12.9 0.1 0.32 11.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2969) GIT_CC PF16559.5 RLN20816.1 - 0.3 11.0 6.6 0.38 10.7 0.5 3.3 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor CTD_bind PF04818.13 RLN20817.1 - 2.5e-12 47.4 0.1 5.1e-10 40.0 0.0 3.4 3 0 0 3 3 3 1 RNA polymerase II-binding domain. HTH_psq PF05225.16 RLN20826.1 - 1.9e-06 27.5 3.7 0.0087 15.8 0.2 3.3 3 0 0 3 3 3 2 helix-turn-helix, Psq domain HTH_23 PF13384.6 RLN20826.1 - 0.063 13.1 4.3 2.5 8.0 0.9 2.7 2 0 0 2 2 2 0 Homeodomain-like domain UPF0175 PF03683.13 RLN20826.1 - 0.15 11.8 0.1 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0175) HTH_28 PF13518.6 RLN20826.1 - 0.79 9.9 3.8 5.7 7.1 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 RLN20826.1 - 0.86 9.1 3.6 5.2 6.6 0.6 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_1 PF00126.27 RLN20826.1 - 2.2 8.3 6.3 4.5 7.3 0.7 2.5 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 RLN20826.1 - 4.3 7.2 7.2 0.41 10.5 0.8 2.3 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain C2 PF00168.30 RLN20827.1 - 4.9e-29 100.6 0.0 2.7e-13 50.1 0.0 2.2 2 0 0 2 2 2 2 C2 domain Copine PF07002.16 RLN20827.1 - 2.9e-20 72.7 0.0 4.3e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Copine Ribosomal_S10 PF00338.22 RLN20828.1 - 9.2e-29 99.6 0.1 1.2e-28 99.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Exo_endo_phos PF03372.23 RLN20829.1 - 1.5e-15 57.4 0.0 3.8e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2183 PF09949.9 RLN20829.1 - 1.4e-07 31.7 0.0 4.5e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) Gemin7 PF11095.8 RLN20829.1 - 0.00043 20.1 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) Laminin_I PF06008.14 RLN20829.1 - 0.021 14.5 0.5 0.039 13.6 0.5 1.3 1 0 0 1 1 1 0 Laminin Domain I GARS_A PF01071.19 RLN20830.1 - 8.7e-81 270.3 0.4 1.7e-80 269.4 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.19 RLN20830.1 - 4.9e-44 150.2 0.1 9.2e-44 149.3 0.1 1.5 1 0 0 1 1 1 1 Formyl transferase GARS_N PF02844.15 RLN20830.1 - 4.4e-32 110.7 1.9 2.7e-31 108.2 0.1 3.3 4 0 0 4 4 4 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 RLN20830.1 - 1e-31 110.2 2.5 2.1e-31 109.2 0.0 2.8 4 0 0 4 4 4 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 RLN20830.1 - 1.1e-30 105.7 1.0 1.1e-30 105.7 1.0 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 RLN20830.1 - 2e-14 54.0 1.2 2e-14 54.0 1.2 3.2 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain AICARFT_IMPCHas PF01808.18 RLN20830.1 - 6.2e-08 32.4 0.1 1.5e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 AICARFT/IMPCHase bienzyme ATP-grasp_3 PF02655.14 RLN20830.1 - 1.2e-05 25.4 0.0 0.0001 22.4 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 RLN20830.1 - 0.00013 21.5 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain E2R135 PF11570.8 RLN20830.1 - 0.0025 18.1 0.1 0.0058 16.9 0.1 1.5 1 0 0 1 1 1 1 Coiled-coil receptor-binding R-domain of colicin E2 CPSase_L_D2 PF02786.17 RLN20830.1 - 0.0096 15.4 0.1 0.022 14.2 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain LAL_C2 PF18603.1 RLN20830.1 - 0.048 13.8 0.4 0.048 13.8 0.4 3.0 3 0 0 3 3 2 0 L-amino acid ligase C-terminal domain 2 MEDS PF14417.6 RLN20830.1 - 0.19 11.5 0.6 0.61 9.9 0.1 2.1 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Abhydrolase_3 PF07859.13 RLN20831.1 - 3.3e-31 108.8 0.1 6.3e-31 107.9 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN20831.1 - 1.8e-09 37.0 0.0 2.6e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase MgtE PF01769.16 RLN20831.1 - 0.79 10.1 8.8 1.3 9.4 8.8 1.3 1 0 0 1 1 1 0 Divalent cation transporter Ncstrn_small PF18266.1 RLN20833.1 - 0.12 12.4 0.1 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Nicastrin small lobe DUF3464 PF11947.8 RLN20833.1 - 3.1 7.5 5.4 1.1 9.0 0.6 2.8 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Alph_Pro_TM PF09608.10 RLN20833.1 - 4.9 6.9 12.0 0.94 9.2 7.0 2.4 1 1 1 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) Neur_chan_memb PF02932.16 RLN20834.1 - 0.47 10.5 4.9 0.77 9.8 4.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ras PF00071.22 RLN20835.1 - 3.8e-06 26.6 0.0 0.00071 19.2 0.0 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 RLN20835.1 - 0.017 15.4 0.2 0.73 10.1 0.1 2.9 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase GREB1 PF15782.5 RLN20835.1 - 1.3 6.0 8.1 1.8 5.6 8.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF962 PF06127.11 RLN20836.1 - 7.8e-21 74.0 2.3 7.6e-16 58.0 2.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF962) HCV_NS4a PF01006.20 RLN20836.1 - 2.9 7.7 5.5 1.7 8.5 0.2 2.4 1 1 1 2 2 2 0 Hepatitis C virus non-structural protein NS4a MnmE_helical PF12631.7 RLN20837.1 - 2.3e-18 67.1 0.4 3.6e-18 66.5 0.4 1.3 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 RLN20837.1 - 6e-14 52.3 2.2 1.6e-07 31.6 0.0 2.3 1 1 1 2 2 2 2 GTP-binding protein TrmE N-terminus WD40 PF00400.32 RLN20838.1 - 5e-20 71.4 28.5 0.0027 18.5 0.1 10.2 10 1 0 10 10 9 6 WD domain, G-beta repeat MMR_HSR1 PF01926.23 RLN20838.1 - 6e-20 71.4 0.0 1.1e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN20838.1 - 6.9e-08 32.2 0.1 1.1e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B ANAPC4_WD40 PF12894.7 RLN20838.1 - 2.7e-06 27.6 0.0 0.042 14.2 0.0 4.2 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain MnmE_helical PF12631.7 RLN20838.1 - 7.6e-05 23.0 0.0 0.00012 22.3 0.0 1.2 1 0 0 1 1 1 1 MnmE helical domain Dynamin_N PF00350.23 RLN20838.1 - 0.00067 19.8 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 RLN20838.1 - 0.0074 16.8 0.0 0.013 16.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 RLN20838.1 - 0.013 15.4 0.2 1 9.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Choline_sulf_C PF12411.8 RLN20838.1 - 0.1 12.4 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal Nucleoporin_N PF08801.11 RLN20838.1 - 0.11 11.3 0.0 20 3.8 0.0 3.6 4 0 0 4 4 4 0 Nup133 N terminal like MMR_HSR1_Xtn PF16897.5 RLN20838.1 - 0.17 11.9 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain His_Phos_1 PF00300.22 RLN20839.1 - 3.3e-06 26.9 0.4 0.0056 16.4 0.0 3.4 3 1 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) MBOAT PF03062.19 RLN20840.1 - 7.9e-31 107.7 16.6 6.5e-30 104.7 16.6 2.0 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 RLN20840.1 - 0.00011 22.4 1.7 0.00011 22.4 1.7 2.3 2 1 0 2 2 2 1 Membrane bound O-acyl transferase family DUF1336 PF07059.12 RLN20841.1 - 6.8e-106 353.5 0.0 2.2e-57 194.8 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1336) DUF2274 PF10038.9 RLN20841.1 - 0.19 12.2 0.1 34 5.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2274) Tcf25 PF04910.14 RLN20842.1 - 8.4e-44 150.1 0.2 1.2e-43 149.6 0.2 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Pox_Ag35 PF03286.14 RLN20842.1 - 0.096 12.5 2.0 0.19 11.5 2.0 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Tcf25 PF04910.14 RLN20843.1 - 1.4e-10 40.8 0.0 1.9e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Pkinase PF00069.25 RLN20844.1 - 0.00066 19.1 0.6 0.001 18.5 0.6 1.2 1 0 0 1 1 1 1 Protein kinase domain CAP_N PF01213.19 RLN20844.1 - 5.2 6.5 11.5 0.48 9.9 6.5 1.6 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Arf PF00025.21 RLN20845.1 - 2.8e-57 193.0 0.0 3.4e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RLN20845.1 - 4.4e-10 39.8 0.1 5.8e-10 39.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RLN20845.1 - 2e-08 34.0 0.0 2.1e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 RLN20845.1 - 1.3e-07 31.1 0.1 1.9e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 RLN20845.1 - 8.1e-06 25.4 0.0 1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 RLN20845.1 - 4.5e-05 23.0 0.0 5.9e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 RLN20845.1 - 0.049 13.7 0.0 0.071 13.2 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATP-synt_F PF01990.17 RLN20846.1 - 2e-21 76.1 0.1 2.2e-21 76.0 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Spt20 PF12090.8 RLN20847.1 - 3.4 7.2 8.5 5.1 6.6 8.5 1.2 1 0 0 1 1 1 0 Spt20 family RRM_5 PF13893.6 RLN20848.1 - 4.3e-24 84.5 0.0 2.6e-08 33.5 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 RLN20848.1 - 2.2e-20 72.3 0.1 3e-07 30.1 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 RLN20848.1 - 2.8e-14 53.1 0.1 5.2e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 RRM-like domain RRM_occluded PF16842.5 RLN20848.1 - 0.0031 17.4 0.1 11 5.9 0.0 3.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 RLN20848.1 - 0.053 13.6 0.0 5.6 7.2 0.0 2.9 3 0 0 3 3 3 0 RNA recognition motif TFIIA PF03153.13 RLN20848.1 - 2.4 8.1 14.6 3.5 7.5 14.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fcf1 PF04900.12 RLN20849.1 - 5.1e-16 58.9 0.0 9.9e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 RLN20849.1 - 4.5e-10 39.8 0.1 8.1e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 PIN like domain Rad21_Rec8_N PF04825.13 RLN20849.1 - 0.085 13.0 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein Pkinase PF00069.25 RLN20850.1 - 1.3e-66 224.7 0.0 2.1e-66 224.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 RLN20850.1 - 1.3e-58 195.0 0.5 5.4e-18 64.8 0.0 4.1 5 0 0 5 5 5 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 RLN20850.1 - 1.5e-33 116.2 0.0 2.7e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN20850.1 - 2.1e-05 24.0 0.0 4.3e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 RLN20850.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 RLN20850.1 - 0.023 14.6 0.0 0.067 13.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 RLN20850.1 - 0.13 11.8 0.1 19 4.8 0.0 2.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF3636 PF12331.8 RLN20850.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) 7TMR-HDED PF07697.11 RLN20850.1 - 2.7 8.1 5.0 2.2 8.3 0.4 2.8 3 1 0 3 3 3 0 7TM-HD extracellular AA_permease_2 PF13520.6 RLN20852.1 - 1.4e-21 76.8 24.8 3.4e-21 75.6 24.8 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN20852.1 - 6e-10 38.3 17.3 6e-10 38.3 17.3 1.6 1 1 1 2 2 2 1 Amino acid permease TPR_14 PF13428.6 RLN20852.1 - 2.2e-07 31.1 6.5 0.68 10.9 0.1 6.1 3 1 2 5 5 5 2 Tetratricopeptide repeat Suf PF05843.14 RLN20852.1 - 5.5e-05 23.3 9.5 0.018 15.1 0.2 4.9 2 1 1 5 5 5 2 Suppressor of forked protein (Suf) HAT PF02184.16 RLN20852.1 - 0.00022 21.1 8.7 0.16 11.9 0.0 5.2 5 0 0 5 5 5 2 HAT (Half-A-TPR) repeat TPR_12 PF13424.6 RLN20852.1 - 0.004 17.4 0.6 0.87 9.9 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 RLN20852.1 - 0.031 14.3 12.0 0.54 10.2 4.7 5.0 3 2 2 5 5 5 0 Mad3/BUB1 homology region 1 TPR_19 PF14559.6 RLN20852.1 - 0.093 13.2 0.0 2 9.0 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat NRDE-2 PF08424.10 RLN20852.1 - 0.39 9.8 13.5 2.3 7.2 1.4 4.5 4 2 0 4 4 4 0 NRDE-2, necessary for RNA interference BOFC_N PF08977.10 RLN20852.1 - 1.4 9.0 3.5 1.5 8.8 0.1 2.9 4 0 0 4 4 4 0 Bypass of Forespore C, N terminal Copine PF07002.16 RLN20854.1 - 6.9e-17 61.6 0.1 2.4e-11 43.5 0.1 2.1 2 0 0 2 2 2 2 Copine Cutinase PF01083.22 RLN20878.1 - 1.6e-43 148.7 3.3 1.9e-43 148.5 3.3 1.0 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.25 RLN20878.1 - 0.06 13.2 0.0 0.1 12.5 0.0 1.3 1 1 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.22 RLN20879.1 - 3.8e-43 147.5 3.0 4.4e-43 147.3 3.0 1.0 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.25 RLN20879.1 - 0.06 13.2 0.0 0.1 12.5 0.0 1.3 1 1 0 1 1 1 0 Lipase (class 3) Kinesin PF00225.23 RLN20880.1 - 1e-103 346.8 0.1 1e-103 346.8 0.1 3.7 4 0 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 RLN20880.1 - 7.1e-19 68.2 0.0 5.8e-18 65.3 0.0 2.8 1 0 0 1 1 1 1 Microtubule binding Mak16 PF04874.14 RLN20881.1 - 1.6e-31 108.9 16.6 1.6e-31 108.9 16.6 2.5 2 1 0 2 2 2 1 Mak16 protein C-terminal region Ribosomal_L28e PF01778.17 RLN20881.1 - 2.5e-31 108.8 0.2 2.5e-31 108.8 0.2 2.6 3 0 0 3 3 3 1 Ribosomal L28e protein family BUD22 PF09073.10 RLN20881.1 - 1.3e-05 24.8 21.8 2e-05 24.1 21.8 1.2 1 0 0 1 1 1 1 BUD22 Exonuc_VII_L PF02601.15 RLN20881.1 - 1.4 8.4 8.6 1.8 8.1 8.6 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit GSHPx PF00255.19 RLN20882.1 - 3.8e-31 106.9 0.1 6e-31 106.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 RLN20882.1 - 0.0021 18.0 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Tho2 PF11262.8 RLN20883.1 - 2 7.5 7.9 2.7 7.1 7.9 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Ribosomal_S13_N PF08069.12 RLN20884.1 - 2.6e-33 113.9 0.7 2.9e-33 113.7 0.7 1.0 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain LAMTOR5 PF16672.5 RLN20885.1 - 2e-05 24.4 0.1 0.0006 19.7 0.1 2.1 1 1 0 1 1 1 1 Ragulator complex protein LAMTOR5 WD40 PF00400.32 RLN20886.1 - 0.044 14.7 0.2 2.1 9.4 0.1 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat PGM_PMM_I PF02878.16 RLN20887.1 - 2.1e-32 111.7 0.0 4.3e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 RLN20887.1 - 1e-22 80.7 0.0 3e-22 79.2 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 RLN20887.1 - 6.8e-15 55.3 0.1 1.4e-14 54.3 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 RLN20887.1 - 7.2e-07 29.3 0.0 2.2e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Arf PF00025.21 RLN20888.1 - 9.8e-67 223.8 0.1 1.1e-66 223.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RLN20888.1 - 6.4e-15 55.4 0.1 8.9e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 RLN20888.1 - 1.7e-11 43.8 0.0 2.1e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 RLN20888.1 - 2.6e-11 43.4 0.1 2.9e-11 43.2 0.1 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 RLN20888.1 - 3.3e-11 42.9 0.5 3.6e-08 33.0 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 RLN20888.1 - 5.3e-07 29.2 0.0 6.7e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RLN20888.1 - 3.8e-06 27.0 0.0 6.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RLN20888.1 - 0.00045 19.8 0.2 0.007 15.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 RLN20888.1 - 0.014 15.9 0.3 0.05 14.1 0.3 1.8 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 RLN20888.1 - 0.018 15.2 0.2 2.1 8.5 0.0 2.2 1 1 0 2 2 2 0 AAA domain MeaB PF03308.16 RLN20888.1 - 0.027 13.5 0.4 0.49 9.3 0.1 2.6 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 RLN20888.1 - 0.044 13.7 0.2 0.74 9.7 0.0 2.1 2 0 0 2 2 2 0 NACHT domain NOG1 PF06858.14 RLN20888.1 - 0.096 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) AAA_14 PF13173.6 RLN20888.1 - 0.1 12.6 0.1 0.18 11.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain BRO1 PF03097.18 RLN20889.1 - 5.4e-18 65.0 1.5 2.9e-15 56.0 1.4 2.1 2 0 0 2 2 2 2 BRO1-like domain PH PF00169.29 RLN20891.1 - 0.006 17.1 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 PH domain zf-C2H2 PF00096.26 RLN20892.1 - 1.4e-16 59.9 28.6 9.1e-05 22.7 2.0 4.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RLN20892.1 - 1.9e-15 56.5 29.7 7.4e-06 26.2 1.1 5.3 5 0 0 5 5 5 4 Zinc-finger double domain BET PF17035.5 RLN20892.1 - 7.7e-11 42.0 0.0 1.6e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation zf-C2H2_4 PF13894.6 RLN20892.1 - 2.7e-09 37.1 26.0 0.003 18.3 1.4 4.7 5 0 0 5 5 4 4 C2H2-type zinc finger zf-TRAF PF02176.18 RLN20892.1 - 0.00015 22.4 9.7 0.011 16.5 2.5 2.3 1 1 1 2 2 2 2 TRAF-type zinc finger zf-C2H2_jaz PF12171.8 RLN20892.1 - 0.00018 21.7 0.5 0.00018 21.7 0.5 4.4 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 RLN20892.1 - 0.14 12.8 0.3 0.14 12.8 0.3 3.7 2 1 2 4 4 4 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 RLN20892.1 - 0.67 10.1 9.6 0.61 10.2 3.0 2.8 2 1 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_9 PF16293.5 RLN20892.1 - 1.2 9.0 3.7 2.7 7.9 0.1 2.6 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 RLN20892.1 - 1.3 9.0 6.6 0.82 9.7 1.0 2.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 RLN20892.1 - 1.5 9.2 12.5 11 6.4 0.6 3.4 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-met PF12874.7 RLN20892.1 - 3.1 8.3 18.0 0.17 12.3 0.7 4.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 RLN20892.1 - 6.2 7.2 13.5 3.3 8.1 2.0 2.8 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ribosomal_S26e PF01283.19 RLN20893.1 - 6e-48 161.8 8.0 6.8e-48 161.6 8.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e UCR_hinge PF02320.16 RLN20894.1 - 7.8e-13 48.4 4.1 1.6e-12 47.5 4.1 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.10 RLN20894.1 - 0.34 11.0 2.7 0.53 10.4 2.7 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like RSN1_7TM PF02714.15 RLN20898.1 - 9.2e-47 159.6 8.9 9.2e-47 159.6 8.9 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 RLN20898.1 - 2.6e-33 115.0 0.0 1.4e-32 112.6 0.0 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 RLN20898.1 - 2.7e-26 92.9 5.3 7.4e-18 65.4 0.5 2.4 1 1 1 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter CDC45 PF02724.14 RLN20898.1 - 8 4.6 16.3 11 4.1 16.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DZR PF12773.7 RLN20899.1 - 0.00014 21.8 8.6 0.062 13.3 0.8 2.6 2 1 0 2 2 2 2 Double zinc ribbon zf-NADH-PPase PF09297.11 RLN20899.1 - 0.0021 17.7 9.0 0.39 10.4 0.2 3.7 3 0 0 3 3 3 3 NADH pyrophosphatase zinc ribbon domain HypA PF01155.19 RLN20899.1 - 0.11 12.6 5.4 1.1 9.4 0.5 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Peptidase_C2 PF00648.21 RLN20899.1 - 0.13 11.3 0.3 0.22 10.5 0.3 1.3 1 0 0 1 1 1 0 Calpain family cysteine protease zinc_ribbon_2 PF13240.6 RLN20899.1 - 0.36 10.6 16.7 1.9 8.3 0.5 3.9 3 1 0 3 3 3 0 zinc-ribbon domain NOB1_Zn_bind PF08772.11 RLN20899.1 - 3.2 8.0 13.9 0.17 12.0 2.3 3.1 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like ADIP PF11559.8 RLN20901.1 - 0.043 13.9 0.1 0.08 13.0 0.1 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding PGI PF00342.19 RLN20902.1 - 1.4e-195 650.5 0.0 1.6e-195 650.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase RCC1 PF00415.18 RLN20903.1 - 1.4e-50 169.7 15.0 1e-12 48.4 0.2 7.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN20903.1 - 3.7e-29 99.9 22.3 6.1e-07 29.1 2.5 7.0 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Methyltransf_25 PF13649.6 RLN20903.1 - 1.3e-09 38.6 0.1 6e-08 33.3 0.1 3.2 1 1 0 1 1 1 1 Methyltransferase domain LRR_4 PF12799.7 RLN20903.1 - 3.8e-08 33.5 0.0 2 9.0 0.0 7.4 7 2 3 10 10 9 2 Leucine Rich repeats (2 copies) Methyltransf_31 PF13847.6 RLN20903.1 - 1.8e-07 31.1 0.0 5.3e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN20903.1 - 2.9e-07 31.1 0.0 1.7e-06 28.7 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN20903.1 - 4.1e-07 30.5 0.0 2.1e-06 28.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 RLN20903.1 - 3.4e-06 26.8 0.0 0.00094 18.9 0.0 2.7 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F MTS PF05175.14 RLN20903.1 - 2e-05 24.2 0.0 7.2e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain LRR_6 PF13516.6 RLN20903.1 - 4.3e-05 23.2 19.9 9.7 6.5 0.2 10.9 12 0 0 12 12 12 1 Leucine Rich repeat Methyltransf_23 PF13489.6 RLN20903.1 - 0.00057 19.7 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN20903.1 - 0.089 12.1 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family LRR_1 PF00560.33 RLN20903.1 - 0.34 11.6 6.4 63 4.7 0.0 5.8 7 0 0 7 7 6 0 Leucine Rich Repeat RRM_1 PF00076.22 RLN20904.1 - 9.9e-21 73.3 0.0 7.4e-11 41.7 0.0 4.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RLN20904.1 - 0.0022 17.8 0.0 0.023 14.5 0.0 2.4 3 0 0 3 3 3 1 Occluded RNA-recognition motif DUF436 PF04260.12 RLN20904.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF436) ANAPC3 PF12895.7 RLN20905.1 - 3.7e-10 39.9 27.2 1.4e-05 25.2 0.7 5.1 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 RLN20905.1 - 4.9e-10 38.8 19.3 0.0053 16.8 0.0 8.0 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 RLN20905.1 - 1.9e-09 37.9 9.8 0.0005 20.5 0.1 5.7 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN20905.1 - 6.8e-08 32.5 2.4 0.00061 19.9 0.1 4.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 RLN20905.1 - 0.00014 22.3 9.0 0.29 11.9 0.1 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN20905.1 - 0.00048 20.7 9.0 1.2 9.8 0.3 5.2 5 2 1 6 6 5 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN20905.1 - 0.0021 18.1 3.7 8 6.6 0.1 3.9 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 RLN20905.1 - 0.0031 17.8 8.1 6.1 7.2 0.0 6.0 5 2 1 7 7 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN20905.1 - 0.0043 17.8 7.3 25 6.0 0.1 6.1 5 3 1 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN20905.1 - 0.0079 16.0 2.8 8.7 6.4 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 RLN20905.1 - 0.0094 16.0 1.7 0.0094 16.0 1.7 4.6 2 2 2 4 4 4 2 Putative TPR-like repeat TPR_1 PF00515.28 RLN20905.1 - 0.016 15.0 14.7 0.07 13.0 0.0 6.7 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 RLN20905.1 - 0.068 13.2 5.6 7.3 6.9 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 RLN20905.1 - 0.082 13.2 5.9 19 5.8 0.1 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF3699 PF12480.8 RLN20905.1 - 0.1 12.8 0.1 2.6 8.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3699) Trehalose_PPase PF02358.16 RLN20906.1 - 5.1e-18 65.1 0.0 6.9e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Clathrin PF00637.20 RLN20907.1 - 1.9e-15 57.0 5.9 2e-14 53.7 1.2 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-RING_UBOX PF13445.6 RLN20907.1 - 0.00056 19.9 1.3 0.0013 18.8 1.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Vps39_1 PF10366.9 RLN20907.1 - 0.038 14.3 2.3 0.095 13.0 0.0 2.7 2 2 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 zf-rbx1 PF12678.7 RLN20907.1 - 0.13 12.5 4.4 0.4 11.0 4.4 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF465 PF04325.13 RLN20907.1 - 0.16 12.0 1.8 11 6.1 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF465) zf-RING_5 PF14634.6 RLN20907.1 - 0.28 11.2 5.2 0.58 10.2 5.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Vps39_2 PF10367.9 RLN20907.1 - 0.4 11.1 2.1 2.1 8.9 0.1 2.6 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_11 PF17123.5 RLN20907.1 - 2 8.2 8.1 6.4 6.6 8.1 1.9 1 1 0 1 1 1 0 RING-like zinc finger zinc_ribbon_12 PF11331.8 RLN20907.1 - 2 8.3 7.9 1.3 8.9 3.9 2.4 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-RING_2 PF13639.6 RLN20907.1 - 7.2 7.0 13.0 0.17 12.2 6.0 2.0 2 0 0 2 2 2 0 Ring finger domain S4 PF01479.25 RLN20908.1 - 1.5e-09 37.4 0.7 1.5e-09 37.4 0.7 2.3 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 RLN20908.1 - 9.3e-06 26.5 2.0 2.1e-05 25.3 0.8 2.2 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain MAPKK1_Int PF08923.10 RLN20909.1 - 1.4e-09 37.8 0.0 3.1e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting MRP-S23 PF10484.9 RLN20909.1 - 0.0059 16.9 0.3 0.021 15.1 0.3 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 Inositol_P PF00459.25 RLN20910.1 - 1e-64 218.7 0.5 1.2e-64 218.5 0.5 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase_glpX PF03320.13 RLN20910.1 - 0.0027 16.6 0.3 0.056 12.3 0.0 2.2 1 1 0 2 2 2 2 Bacterial fructose-1,6-bisphosphatase, glpX-encoded EXS PF03124.14 RLN20911.1 - 5.6e-47 160.7 20.8 2.1e-28 99.6 12.9 2.1 1 1 1 2 2 2 2 EXS family GAF PF01590.26 RLN20914.1 - 1.9e-08 35.0 0.3 6e-08 33.4 0.3 1.9 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 RLN20914.1 - 1.6e-05 25.2 0.0 5.5e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 GAF domain FYVE PF01363.21 RLN20914.1 - 3.2e-05 24.0 15.9 7.3e-05 22.8 15.9 1.6 1 0 0 1 1 1 1 FYVE zinc finger GAF_3 PF13492.6 RLN20914.1 - 0.00022 21.6 0.1 0.00059 20.2 0.1 1.7 1 0 0 1 1 1 1 GAF domain FYVE_2 PF02318.16 RLN20914.1 - 0.071 13.3 7.4 0.27 11.4 7.4 2.0 1 0 0 1 1 1 0 FYVE-type zinc finger E3_UFM1_ligase PF09743.9 RLN20915.1 - 6.7e-79 265.3 0.1 9.9e-79 264.8 0.1 1.3 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 MarR_2 PF12802.7 RLN20915.1 - 0.0001 22.1 0.6 0.13 12.2 0.1 3.3 2 1 0 2 2 2 2 MarR family Sporozoite_P67 PF05642.11 RLN20915.1 - 0.077 11.1 2.5 0.12 10.4 2.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HTH_IclR PF09339.10 RLN20915.1 - 0.57 10.0 4.6 1.4 8.8 0.2 3.9 4 0 0 4 4 4 0 IclR helix-turn-helix domain Rad9 PF04139.13 RLN20916.1 - 9.4e-35 120.2 1.0 1.4e-34 119.7 1.0 1.2 1 0 0 1 1 1 1 Rad9 SNF2_N PF00176.23 RLN20967.1 - 6.4e-49 166.5 0.0 1.2e-48 165.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN20967.1 - 4.3e-17 62.5 0.2 1.4e-16 60.8 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN20967.1 - 0.0011 19.0 0.0 0.0039 17.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 RLN20967.1 - 0.0082 15.4 0.2 0.053 12.7 0.2 2.2 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-C2H2_10 PF16588.5 RLN20967.1 - 0.16 11.7 1.5 0.34 10.7 1.5 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger FAA_hydrolase_N PF09298.11 RLN20967.1 - 1.1 9.5 2.9 4 7.7 2.3 2.3 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal AMP-binding PF00501.28 RLN20969.1 - 2e-80 270.5 0.0 3.4e-80 269.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Aminotran_1_2 PF00155.21 RLN20969.1 - 8.4e-51 173.2 0.0 1.5e-50 172.4 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 RLN20969.1 - 8.7e-07 28.2 0.0 1.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V PP-binding PF00550.25 RLN20969.1 - 1.1e-06 28.8 0.0 3.2e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Cys_Met_Meta_PP PF01053.20 RLN20969.1 - 0.0043 15.6 0.0 0.013 14.0 0.0 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 RLN20969.1 - 0.012 14.4 0.0 0.049 12.4 0.0 1.9 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain AA_permease_2 PF13520.6 RLN20970.1 - 3e-24 85.6 16.9 3e-24 85.6 16.9 2.3 2 1 0 2 2 2 1 Amino acid permease EF-hand_7 PF13499.6 RLN20970.1 - 2.4e-15 56.7 1.0 2.3e-09 37.6 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN20970.1 - 9.5e-14 49.8 0.2 0.0017 17.8 0.1 4.8 5 0 0 5 5 5 3 EF hand AA_permease PF00324.21 RLN20970.1 - 1.5e-12 46.9 13.3 2e-11 43.2 11.1 2.4 2 1 0 2 2 2 1 Amino acid permease EF-hand_8 PF13833.6 RLN20970.1 - 3.1e-11 43.0 1.3 8.2e-09 35.2 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN20970.1 - 8.5e-10 37.8 0.1 0.16 12.0 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain AA_permease_C PF13906.6 RLN20970.1 - 8.8e-08 32.1 4.6 8.8e-08 32.1 4.6 2.7 2 0 0 2 2 2 1 C-terminus of AA_permease EF-hand_5 PF13202.6 RLN20970.1 - 4.5e-07 29.1 0.1 0.027 14.0 0.0 3.8 3 0 0 3 3 3 2 EF hand BUD22 PF09073.10 RLN20970.1 - 0.033 13.5 6.1 0.046 13.1 6.1 1.1 1 0 0 1 1 1 0 BUD22 EFhand_Ca_insen PF08726.10 RLN20970.1 - 0.094 12.8 0.0 0.63 10.2 0.0 2.2 2 0 0 2 2 2 0 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 RLN20970.1 - 0.12 13.3 0.0 0.97 10.3 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain TMEM237 PF15383.6 RLN20970.1 - 0.16 11.0 0.1 0.38 9.8 0.1 1.6 1 0 0 1 1 1 0 Transmembrane protein 237 Tudor-knot PF11717.8 RLN20971.1 - 4.1e-06 26.6 0.1 1.5e-05 24.7 0.1 2.0 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MatE PF01554.18 RLN20972.1 - 7e-53 178.6 36.3 8.5e-31 106.8 13.5 2.2 2 0 0 2 2 2 2 MatE Glyco_hydro_61 PF03443.14 RLN20974.1 - 8.3e-08 32.4 0.1 1.3e-07 31.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 RLN20974.1 - 5.6e-06 27.2 3.8 3.9e-05 24.4 0.5 2.6 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Period_C PF12114.8 RLN20974.1 - 9.2 5.8 9.9 18 4.8 9.9 1.5 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Pkinase PF00069.25 RLN20975.1 - 1.2e-45 156.0 0.0 1.5e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN20975.1 - 1.3e-41 142.6 0.0 1.7e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN20975.1 - 0.0018 18.3 0.0 0.033 14.1 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF4448 PF14610.6 RLN20975.1 - 0.053 13.3 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Haspin_kinase PF12330.8 RLN20975.1 - 0.056 12.4 0.0 0.087 11.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain LRR_4 PF12799.7 RLN20975.1 - 0.062 13.7 1.1 0.1 13.1 0.1 1.9 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) TMEM154 PF15102.6 RLN20975.1 - 0.092 12.7 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Adeno_E3_CR2 PF02439.15 RLN20975.1 - 0.096 12.5 1.4 0.17 11.7 1.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CD34_antigen PF06365.12 RLN20975.1 - 0.11 12.1 0.0 0.52 9.9 0.0 2.0 2 0 0 2 2 2 0 CD34/Podocalyxin family zf-RanBP PF00641.18 RLN20976.1 - 0.0047 16.2 2.3 0.0087 15.4 2.3 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others LRR_8 PF13855.6 RLN20976.1 - 0.062 13.1 0.5 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 RLN20976.1 - 0.088 13.3 1.9 4.5 7.8 0.1 3.1 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) DUF1117 PF06547.12 RLN20977.1 - 0.078 13.5 0.9 0.38 11.3 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1117) HECT PF00632.25 RLN20983.1 - 2.9e-72 243.7 0.0 4.3e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 RLN20983.1 - 5.7e-05 22.3 3.4 8.9e-05 21.7 3.4 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 RLN20983.1 - 0.006 16.0 0.2 0.011 15.1 0.2 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain BK_channel_a PF03493.18 RLN20984.1 - 3.7e-20 71.9 0.0 2.3e-19 69.4 0.0 2.1 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit TrkA_N PF02254.18 RLN20984.1 - 4.5e-07 30.1 0.4 0.033 14.4 0.0 2.9 3 0 0 3 3 3 2 TrkA-N domain Castor_Poll_mid PF06241.12 RLN20984.1 - 0.024 14.6 0.0 0.27 11.2 0.0 2.4 2 0 0 2 2 2 0 Castor and Pollux, part of voltage-gated ion channel TrkA_C PF02080.21 RLN20984.1 - 0.083 12.7 0.0 21 5.0 0.0 2.7 2 0 0 2 2 2 0 TrkA-C domain HA PF03457.14 RLN20985.1 - 1.4e-22 79.8 1.6 1.8e-06 28.2 0.1 4.3 4 0 0 4 4 4 4 Helicase associated domain Glyco_hydro_31 PF01055.26 RLN20986.1 - 3.9e-120 402.0 0.0 4.9e-120 401.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 RLN20986.1 - 3.2e-26 91.8 0.0 6.7e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 RLN20986.1 - 7.6e-07 29.4 0.0 2.5e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Trefoil PF00088.18 RLN20986.1 - 2.9e-06 27.1 9.8 0.005 16.7 0.9 2.6 2 0 0 2 2 2 2 Trefoil (P-type) domain DUF4006 PF13179.6 RLN20986.1 - 0.042 13.8 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Fibrillin_U_N PF18193.1 RLN20986.1 - 0.056 13.6 0.6 0.16 12.1 0.6 1.7 1 0 0 1 1 1 0 Fibrillin 1 unique N-terminal domain Adeno_E3_CR2 PF02439.15 RLN20986.1 - 0.16 11.8 1.1 0.26 11.1 1.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 KIAA1430 PF13879.6 RLN20987.1 - 5.4e-17 62.4 2.8 1.3e-16 61.2 2.8 1.7 1 0 0 1 1 1 1 KIAA1430 homologue ANAPC4_WD40 PF12894.7 RLN20988.1 - 2.7e-07 30.8 0.0 0.0093 16.2 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RLN20988.1 - 6e-06 26.9 5.1 0.09 13.7 0.3 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.11 RLN20988.1 - 0.064 13.1 0.0 21 4.9 0.0 3.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF4611 PF15387.6 RLN20988.1 - 0.47 10.7 4.1 1.4 9.2 4.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) SRRM_C PF15230.6 RLN20988.1 - 2.1 9.0 6.2 7.1 7.3 1.0 3.2 3 0 0 3 3 3 0 Serine/arginine repetitive matrix protein C-terminus Cupin_4 PF08007.12 RLN20989.1 - 3e-06 26.9 0.3 0.00097 18.7 0.1 2.4 2 0 0 2 2 2 2 Cupin superfamily protein RB_A PF01858.17 RLN20990.1 - 0.058 13.2 0.5 1.4 8.7 0.0 2.0 1 1 0 2 2 2 0 Retinoblastoma-associated protein A domain Choline_transpo PF04515.12 RLN20991.1 - 1.2e-92 310.6 24.0 1.2e-92 310.6 24.0 2.9 3 0 0 3 3 3 2 Plasma-membrane choline transporter Glyco_transf_22 PF03901.17 RLN20992.1 - 1.4e-45 156.3 26.0 1.8e-45 156.0 26.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family EpsG PF14897.6 RLN20992.1 - 0.71 9.1 9.3 0.2 10.9 6.0 1.8 2 1 0 2 2 2 0 EpsG family Ank_4 PF13637.6 RLN21015.1 - 5.2e-09 36.5 0.1 0.00058 20.4 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN21015.1 - 6.2e-07 29.9 0.0 0.0047 17.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN21015.1 - 3e-06 27.1 0.3 0.063 13.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Leu_zip PF15294.6 RLN21015.1 - 4.8e-06 26.3 19.9 4.8e-06 26.3 19.9 4.1 2 2 2 4 4 3 2 Leucine zipper Ank PF00023.30 RLN21015.1 - 0.00011 22.5 0.4 0.12 12.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 RLN21015.1 - 0.031 14.6 0.5 1.7 9.0 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) FlaC_arch PF05377.11 RLN21015.1 - 1.1 9.7 3.0 3 8.3 1.4 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Ribosomal_60s PF00428.19 RLN21015.1 - 2.6 8.7 9.2 22 5.7 9.2 2.6 1 1 0 1 1 1 0 60s Acidic ribosomal protein NPV_P10 PF05531.12 RLN21015.1 - 4.1 7.9 5.7 1.2 9.7 0.7 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SET PF00856.28 RLN21015.1 - 5.6 7.3 9.4 9.4 6.6 0.1 2.5 2 1 0 2 2 2 0 SET domain FapA PF03961.13 RLN21015.1 - 9.7 4.7 14.8 0.055 12.1 5.8 1.9 2 0 0 2 2 2 0 Flagellar Assembly Protein A Ribosomal_L39 PF00832.20 RLN21016.1 - 2.1e-11 43.2 2.7 3.1e-11 42.7 2.7 1.2 1 0 0 1 1 1 1 Ribosomal L39 protein MOFRL PF05161.13 RLN21016.1 - 0.024 14.8 0.9 0.024 14.8 0.9 2.4 1 1 1 2 2 2 0 MOFRL family PIP5K PF01504.18 RLN21017.1 - 3.7e-67 226.4 0.0 6.5e-67 225.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_2 PF00002.24 RLN21017.1 - 0.00048 19.5 4.7 0.00048 19.5 4.7 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Yip1 PF04893.17 RLN21017.1 - 0.04 13.6 0.3 0.04 13.6 0.3 2.4 2 0 0 2 2 2 0 Yip1 domain DUF373 PF04123.13 RLN21017.1 - 7.9 5.8 8.3 0.23 10.9 0.5 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF373) Plasmodium_Vir PF05795.11 RLN21018.1 - 0.26 10.7 7.2 0.13 11.7 0.3 3.0 3 0 0 3 3 3 0 Plasmodium vivax Vir protein FYVE PF01363.21 RLN21032.1 - 0.027 14.6 8.5 0.056 13.6 8.5 1.5 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN21032.1 - 0.08 13.2 5.2 0.15 12.3 5.2 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger IBR PF01485.21 RLN21032.1 - 0.082 13.1 3.7 0.18 12.1 3.7 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Utp12 PF04003.12 RLN21033.1 - 0.025 14.9 0.1 0.075 13.3 0.1 1.7 1 0 0 1 1 1 0 Dip2/Utp12 Family Pyr_redox_2 PF07992.14 RLN21035.1 - 0.031 13.5 0.0 0.04 13.2 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase B12-binding PF02310.19 RLN21035.1 - 0.073 13.1 0.1 0.12 12.4 0.0 1.4 2 0 0 2 2 2 0 B12 binding domain CAP PF00188.26 RLN21036.1 - 1.9e-20 74.0 4.0 1.9e-20 74.0 4.0 1.4 2 0 0 2 2 2 1 Cysteine-rich secretory protein family EVI2A PF05399.11 RLN21036.1 - 1 8.9 5.1 1.8 8.1 5.1 1.4 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Roughex PF06020.11 RLN21036.1 - 5.9 5.9 11.7 9.9 5.1 11.7 1.3 1 0 0 1 1 1 0 Drosophila roughex protein CAP PF00188.26 RLN21037.1 - 6e-20 72.4 3.9 1.1e-19 71.5 3.9 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MSA-2c PF12238.8 RLN21037.1 - 3.9 7.4 8.7 2.4 8.1 7.1 1.5 2 0 0 2 2 2 0 Merozoite surface antigen 2c CAP PF00188.26 RLN21038.1 - 2.6e-19 70.3 4.7 3.9e-19 69.7 4.7 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Sulfatase_C PF14707.6 RLN21038.1 - 0.021 15.5 0.5 0.053 14.2 0.5 1.7 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase ABC1 PF03109.16 RLN21039.1 - 1.7e-24 86.3 0.0 3.2e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 RLN21039.1 - 3.5e-05 23.5 0.2 0.46 10.1 0.0 3.2 2 1 1 3 3 3 2 RIO1 family APH PF01636.23 RLN21039.1 - 0.0015 18.6 0.6 0.042 13.8 0.0 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family Helitron_like_N PF14214.6 RLN21040.1 - 8e-12 45.8 0.1 1.8e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Pkinase PF00069.25 RLN21041.1 - 2.4e-49 168.1 0.0 3.3e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN21041.1 - 2.1e-41 142.0 0.0 2.8e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4690 PF15756.5 RLN21041.1 - 0.011 16.3 3.7 0.012 16.2 1.8 2.1 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Podoplanin PF05808.11 RLN21041.1 - 0.012 15.7 2.9 0.012 15.7 2.9 1.9 2 0 0 2 2 2 0 Podoplanin EphA2_TM PF14575.6 RLN21041.1 - 0.022 15.6 0.4 0.048 14.5 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 RLN21041.1 - 0.048 12.5 0.1 0.069 12.0 0.1 1.1 1 0 0 1 1 1 0 Amnionless DUF2771 PF10969.8 RLN21041.1 - 0.13 12.3 0.3 0.13 12.3 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2771) FeoB_associated PF12669.7 RLN21041.1 - 8.4 6.9 8.0 0.59 10.6 1.6 2.2 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Pkinase PF00069.25 RLN21042.1 - 8.3e-49 166.3 0.0 1.2e-48 165.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN21042.1 - 1.4e-41 142.6 0.0 1.9e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2207 PF09972.9 RLN21042.1 - 0.013 14.3 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pkinase PF00069.25 RLN21043.1 - 2.7e-49 167.9 0.0 5.3e-49 167.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN21043.1 - 3.7e-42 144.4 0.0 4.9e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2460 PF09343.10 RLN21043.1 - 0.027 14.0 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 2217 (DUF2460) TMEM51 PF15345.6 RLN21043.1 - 0.035 14.0 0.0 0.053 13.4 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 EphA2_TM PF14575.6 RLN21043.1 - 0.12 13.3 0.0 0.24 12.3 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4006 PF13179.6 RLN21043.1 - 0.12 12.3 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Kdo PF06293.14 RLN21043.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RLN21043.1 - 0.19 10.6 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF202 PF02656.15 RLN21043.1 - 1.1 9.8 3.2 0.48 10.9 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Pkinase PF00069.25 RLN21044.1 - 3.7e-34 118.3 0.0 4.5e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN21044.1 - 1.8e-26 93.0 0.0 2.3e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN21044.1 - 0.0025 16.6 0.1 0.0033 16.3 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN21044.1 - 0.032 14.2 0.0 0.089 12.7 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN21044.1 - 0.077 12.3 0.2 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RLN21044.1 - 0.088 11.7 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Sigma70_r4_2 PF08281.12 RLN21074.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 RLN21074.1 - 0.0021 17.8 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_1 PF01527.20 RLN21074.1 - 0.0024 18.1 0.1 0.0034 17.6 0.1 1.3 1 1 0 1 1 1 1 Transposase HTH_29 PF13551.6 RLN21074.1 - 0.015 15.3 0.1 0.021 14.9 0.1 1.2 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 RLN21074.1 - 0.028 14.6 0.3 0.031 14.4 0.3 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_ECF PF07638.11 RLN21074.1 - 0.031 14.2 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 ECF sigma factor Ion_trans PF00520.31 RLN21075.1 - 4.6e-167 553.3 72.5 1.1e-48 165.6 9.8 5.4 4 1 1 5 5 5 5 Ion transport protein PKD_channel PF08016.12 RLN21075.1 - 2.9e-09 36.1 64.8 3.8e-06 25.8 1.5 9.9 6 3 2 9 9 9 6 Polycystin cation channel EF-hand_7 PF13499.6 RLN21077.1 - 0.00011 22.6 0.0 0.00025 21.4 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair Ins145_P3_rec PF08709.11 RLN21077.1 - 0.18 10.9 0.0 10 5.3 0.0 2.4 2 0 0 2 2 2 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Arm PF00514.23 RLN21078.1 - 0.0015 18.5 3.7 0.88 9.7 0.0 4.0 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Ribosomal_L6e PF01159.19 RLN21078.1 - 0.24 11.9 2.0 3.7 8.1 0.1 2.8 3 0 0 3 3 3 0 Ribosomal protein L6e HEAT_EZ PF13513.6 RLN21078.1 - 4.1 8.0 20.0 2.8 8.5 0.2 6.1 6 0 0 6 6 6 0 HEAT-like repeat p25-alpha PF05517.12 RLN21080.1 - 0.00012 22.3 0.0 0.63 10.2 0.0 2.6 2 0 0 2 2 2 2 p25-alpha PA PF02225.22 RLN21081.1 - 4.5e-05 23.4 0.4 0.00016 21.6 0.0 2.1 2 0 0 2 2 2 1 PA domain PDZ_6 PF17820.1 RLN21081.1 - 7.2e-05 22.6 0.1 0.055 13.3 0.0 2.9 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 RLN21081.1 - 0.00089 19.6 0.0 0.023 15.1 0.0 2.5 2 0 0 2 2 2 1 PDZ domain Aminotran_1_2 PF00155.21 RLN21082.1 - 1.5e-69 235.0 0.0 1.8e-69 234.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 RLN21082.1 - 2e-05 24.0 0.0 2.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 RLN21082.1 - 3.6e-05 22.9 0.0 6.1e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 RLN21082.1 - 0.0001 21.0 0.0 0.00015 20.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Flg_hook PF02120.16 RLN21082.1 - 0.006 16.4 0.1 0.086 12.7 0.0 2.9 3 0 0 3 3 3 1 Flagellar hook-length control protein FliK DegT_DnrJ_EryC1 PF01041.17 RLN21082.1 - 0.0067 15.8 0.6 0.014 14.7 0.6 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 RLN21082.1 - 0.088 11.3 0.0 0.13 10.7 0.0 1.3 1 0 0 1 1 1 0 Methionine gamma-lyase THF_DHG_CYH_C PF02882.19 RLN21083.1 - 2.4e-63 212.2 0.0 3.4e-63 211.7 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 RLN21083.1 - 3e-25 88.8 0.1 1.2e-23 83.6 0.1 2.3 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Hexapep PF00132.24 RLN21084.1 - 1.8e-08 33.7 3.6 0.0012 18.5 1.1 4.3 2 2 2 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 RLN21084.1 - 5.2e-05 22.9 7.7 0.13 12.0 3.7 2.9 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase ALF PF03752.13 RLN21095.1 - 0.021 14.8 0.8 0.061 13.3 0.8 1.7 1 0 0 1 1 1 0 Short repeats of unknown function Sugar_tr PF00083.24 RLN21103.1 - 4.5e-119 398.3 19.8 7.2e-119 397.6 19.8 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN21103.1 - 4.1e-25 88.5 56.6 8.7e-23 80.8 31.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 60KD_IMP PF02096.20 RLN21103.1 - 0.31 10.9 7.6 5 7.0 2.2 3.3 3 0 0 3 3 3 0 60Kd inner membrane protein ADH_N PF08240.12 RLN21104.1 - 1.5e-25 89.2 3.3 1.5e-25 89.2 3.3 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN21104.1 - 3.8e-23 81.9 0.1 6.1e-23 81.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN21104.1 - 0.0017 19.4 0.0 0.0033 18.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 RLN21104.1 - 0.033 13.6 0.1 0.053 13.0 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Viral_Beta_CD PF04530.12 RLN21104.1 - 0.046 14.0 0.2 0.046 14.0 0.2 1.9 2 0 0 2 2 2 0 Viral Beta C/D like family Methyltransf_15 PF09445.10 RLN21104.1 - 0.13 11.8 0.2 0.22 11.1 0.2 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase ADH_zinc_N PF00107.26 RLN21105.1 - 2.1e-25 89.2 0.4 3.6e-25 88.4 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN21105.1 - 3.8e-25 87.9 1.8 3.8e-25 87.9 1.8 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 RLN21105.1 - 1.4e-06 29.4 0.1 2.4e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 RLN21105.1 - 0.052 13.0 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 RLN21105.1 - 0.059 12.7 0.3 0.12 11.7 0.3 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.21 RLN21105.1 - 0.15 11.5 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 RLN21106.1 - 4.3e-25 88.2 0.4 6.8e-25 87.5 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN21106.1 - 5.3e-25 87.4 3.2 5.3e-25 87.4 3.2 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 RLN21106.1 - 9.4e-07 30.0 0.1 1.5e-06 29.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 RLN21106.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Ret2_MD PF18528.1 RLN21106.1 - 0.19 12.2 0.0 37 4.8 0.0 2.6 2 0 0 2 2 2 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Viral_Beta_CD PF04530.12 RLN21106.1 - 4.1 7.7 5.9 0.38 11.1 0.5 2.0 1 1 1 2 2 2 0 Viral Beta C/D like family PX PF00787.24 RLN21107.1 - 2e-09 37.4 0.3 0.011 15.7 0.2 4.3 3 2 0 3 3 3 3 PX domain PRP4 PF08799.11 RLN21107.1 - 0.0079 15.7 1.1 0.017 14.7 0.0 2.2 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like NLE PF08154.12 RLN21107.1 - 0.2 12.2 0.0 29 5.3 0.0 2.9 3 0 0 3 3 3 0 NLE (NUC135) domain zf-CHCC PF10276.9 RLN21107.1 - 0.45 10.6 7.8 10 6.3 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger domain PX PF00787.24 RLN21108.1 - 0.037 14.0 0.1 0.14 12.2 0.1 2.0 1 1 0 1 1 1 0 PX domain DUF547 PF04784.14 RLN21108.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF547 zf_PR_Knuckle PF18445.1 RLN21108.1 - 0.62 9.9 2.1 2.4 8.1 2.1 1.9 1 1 0 1 1 1 0 PR zinc knuckle motif PX PF00787.24 RLN21109.1 - 0.00062 19.7 0.2 0.0017 18.3 0.2 1.9 1 1 0 1 1 1 1 PX domain MutS_V PF00488.21 RLN21110.1 - 1.1e-36 126.7 0.5 2.5e-36 125.5 0.5 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 RLN21110.1 - 2.3e-24 86.7 0.2 6.8e-24 85.1 0.2 1.8 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.20 RLN21110.1 - 2e-17 63.4 0.0 5.2e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain I DUF2183 PF09949.9 RLN21110.1 - 0.1 12.9 0.2 1.4 9.3 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2183) GlcNAc PF11397.8 RLN21111.1 - 3.1e-46 158.5 0.1 5.6e-38 131.3 0.0 2.4 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) PCI PF01399.27 RLN21111.1 - 1e-12 48.5 0.2 2.6e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 PCI domain SR-25 PF10500.9 RLN21113.1 - 0.25 10.9 12.4 0.38 10.3 12.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cu-oxidase_2 PF07731.14 RLN21115.1 - 1.8e-21 76.3 2.3 1.8e-21 76.3 2.3 2.6 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN21115.1 - 8.1e-13 48.4 0.2 1.1e-09 38.4 0.5 3.4 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 RLN21115.1 - 0.0022 18.1 0.0 0.0052 16.9 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase MatE PF01554.18 RLN21117.1 - 4.2e-38 130.5 40.6 4.5e-20 71.9 16.8 2.3 2 0 0 2 2 2 2 MatE PH PF00169.29 RLN21118.1 - 1.5e-67 224.7 1.3 2.2e-12 47.4 0.0 7.2 6 1 0 6 6 6 6 PH domain PH_8 PF15409.6 RLN21118.1 - 3.9e-25 87.9 0.2 9.1e-05 22.7 0.0 6.3 6 0 0 6 6 6 6 Pleckstrin homology domain PH_11 PF15413.6 RLN21118.1 - 1.9e-16 60.4 22.9 0.03 14.8 0.0 8.6 6 5 2 9 9 9 6 Pleckstrin homology domain PH_9 PF15410.6 RLN21118.1 - 0.00018 21.9 0.6 49 4.3 0.0 6.4 7 1 1 8 8 8 0 Pleckstrin homology domain PH_2 PF08458.10 RLN21118.1 - 0.063 13.6 0.4 19 5.7 0.0 3.6 3 0 0 3 3 3 0 Plant pleckstrin homology-like region Retrotran_gag_3 PF14244.6 RLN21118.1 - 0.097 12.5 1.7 13 5.6 0.2 2.6 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 RLN21118.1 - 2.2 8.0 4.8 5.7 6.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) Tom37 PF10568.9 RLN21119.1 - 6.4e-21 75.0 0.0 1.3e-20 74.0 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 RLN21119.1 - 3.5e-14 53.3 0.0 6.2e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 RLN21119.1 - 8.4e-11 41.5 0.0 2e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RLN21119.1 - 1.1e-06 28.6 0.0 6.8e-06 26.0 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GTA_holin_3TM PF11351.8 RLN21119.1 - 0.0094 16.5 0.2 0.017 15.7 0.2 1.4 1 0 0 1 1 1 1 Holin of 3TMs, for gene-transfer release Cwf_Cwc_15 PF04889.12 RLN21119.1 - 0.045 13.5 3.9 0.078 12.7 3.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GST_C_3 PF14497.6 RLN21119.1 - 0.045 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NOA36 PF06524.12 RLN21119.1 - 0.88 8.8 6.4 1.2 8.4 6.4 1.2 1 0 0 1 1 1 0 NOA36 protein Myb_DNA-binding PF00249.31 RLN21120.1 - 1.3e-14 54.1 7.3 2.9e-09 37.0 1.1 3.1 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN21120.1 - 1.3e-12 47.7 0.7 5.9e-07 29.6 0.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Peptidase_U40 PF10464.9 RLN21120.1 - 0.02 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase U40 NOA36 PF06524.12 RLN21120.1 - 0.89 8.8 7.0 1.5 8.0 7.0 1.3 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 RLN21120.1 - 0.99 9.1 11.4 0.11 12.2 5.0 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 RLN21120.1 - 4.2 7.8 12.0 9.1 6.8 12.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3246 PF11596.8 RLN21120.1 - 4.3 6.7 10.4 0.96 8.8 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) YL1 PF05764.13 RLN21120.1 - 5.8 6.9 14.3 0.61 10.2 8.7 2.0 2 0 0 2 2 2 0 YL1 nuclear protein Telomere_reg-2 PF10193.9 RLN21121.1 - 1.3e-24 86.7 1.1 2.9e-24 85.6 1.1 1.6 1 0 0 1 1 1 1 Telomere length regulation protein WRW PF10206.9 RLN21121.1 - 0.087 13.2 0.0 0.32 11.4 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial F1F0-ATP synthase, subunit f Ank_4 PF13637.6 RLN21123.1 - 2.2e-39 133.3 25.7 2.4e-06 28.0 0.3 11.3 8 3 4 12 12 12 10 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN21123.1 - 4.9e-37 126.4 19.7 2.3e-09 37.7 0.2 8.6 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN21123.1 - 3.1e-26 91.1 36.7 0.019 15.3 0.1 16.6 5 2 12 18 18 18 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN21123.1 - 8.8e-26 87.1 15.3 0.58 10.9 0.0 17.2 17 1 1 18 18 18 6 Ankyrin repeat DUF5049 PF16468.5 RLN21123.1 - 1.7e-10 40.6 0.9 8.1 6.4 0.0 8.9 6 3 4 10 10 10 4 Domain of unknown function (DUF5049) Ank PF00023.30 RLN21123.1 - 3.5e-05 24.1 8.0 29 5.3 0.3 9.9 4 2 1 5 5 5 0 Ankyrin repeat DUF3322 PF11795.8 RLN21123.1 - 0.0022 18.0 3.6 31 4.5 0.0 6.3 4 2 1 6 6 6 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) MatE PF01554.18 RLN21124.1 - 2.4e-38 131.3 35.6 1.5e-21 76.7 10.9 2.8 3 0 0 3 3 3 2 MatE Tim17 PF02466.19 RLN21128.1 - 5e-06 26.9 1.5 8.9e-06 26.1 1.5 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3966 PF13110.6 RLN21128.1 - 0.1 12.6 0.2 0.2 11.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) Peptidase_S10 PF00450.22 RLN21130.1 - 8.6e-97 325.2 0.0 1.7e-96 324.2 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase ALS_ss_C PF10369.9 RLN21131.1 - 2e-24 85.6 0.0 4.8e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 Small subunit of acetolactate synthase ACT PF01842.25 RLN21131.1 - 6.8e-10 38.6 0.2 1.9e-09 37.2 0.1 1.9 2 0 0 2 2 2 1 ACT domain ACT_5 PF13710.6 RLN21131.1 - 2.8e-05 23.9 0.1 6.2e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 ACT domain Rap_GAP PF02145.15 RLN21135.1 - 2.4e-08 33.7 0.0 6.8e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 Rap/ran-GAP Rad52_Rad22 PF04098.15 RLN21136.1 - 3.2e-39 134.3 0.0 4.6e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein PI3_PI4_kinase PF00454.27 RLN21137.1 - 3.9e-32 112.0 0.0 1.4e-23 84.0 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PH PF00169.29 RLN21137.1 - 0.00033 21.1 0.0 0.0013 19.2 0.0 2.0 2 0 0 2 2 2 1 PH domain DUF4135 PF13575.6 RLN21137.1 - 0.051 12.9 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Glyco_hydro_17 PF00332.18 RLN21150.1 - 1.2e-17 64.5 1.0 3.3e-10 40.0 0.2 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Herpes_capsid PF06112.11 RLN21150.1 - 2.8 8.0 6.3 5.6 7.0 6.3 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Pkinase_Tyr PF07714.17 RLN21151.1 - 4.7e-44 150.6 0.0 1.4e-34 119.6 0.0 3.8 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN21151.1 - 2e-39 135.6 0.0 8.2e-32 110.6 0.0 3.6 3 1 0 3 3 3 3 Protein kinase domain Kinase-like PF14531.6 RLN21151.1 - 0.028 13.7 0.0 0.39 10.0 0.0 2.3 2 0 0 2 2 2 0 Kinase-like TPR_1 PF00515.28 RLN21177.1 - 1.1e-17 62.9 6.9 6.3e-09 35.3 0.3 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN21177.1 - 9.2e-17 59.7 6.7 6.4e-09 35.3 0.4 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN21177.1 - 9.1e-15 54.1 6.0 5.7e-06 25.9 0.1 3.1 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 RLN21177.1 - 1.3e-14 53.1 4.3 6.5e-07 29.1 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN21177.1 - 2.1e-10 39.9 3.0 5.7e-05 22.9 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 RLN21177.1 - 5.7e-10 39.7 2.3 7.4e-07 29.7 0.4 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN21177.1 - 6.8e-10 38.9 2.2 0.0011 19.6 0.2 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 RLN21177.1 - 6.7e-08 32.7 3.8 0.00024 21.4 0.3 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN21177.1 - 8.1e-08 32.7 0.4 6.9e-05 23.3 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN21177.1 - 3.3e-06 27.1 0.8 1.7e-05 24.9 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN21177.1 - 1.7e-05 24.9 4.8 0.0014 18.9 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN21177.1 - 4.6e-05 23.1 2.7 0.0016 18.3 0.4 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 RLN21177.1 - 0.00025 21.0 1.0 0.16 12.1 0.0 3.2 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 RLN21177.1 - 0.00046 20.6 0.4 3 8.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN21177.1 - 0.098 12.7 0.5 0.44 10.6 0.1 2.2 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat LRR_4 PF12799.7 RLN21178.1 - 9.4e-13 48.1 17.4 6.1e-06 26.5 2.2 3.9 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN21178.1 - 4.4e-12 45.8 3.7 6.2e-09 35.6 0.8 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 RLN21178.1 - 3.5e-09 36.3 25.7 1.7e-05 24.5 5.6 3.5 1 1 2 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 RLN21178.1 - 0.035 14.1 11.5 3.2 8.0 0.0 5.5 6 0 0 6 6 6 0 Leucine Rich repeat EF-hand_7 PF13499.6 RLN21179.1 - 5.2e-19 68.5 1.9 4.3e-10 39.9 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN21179.1 - 4.8e-18 63.3 2.8 4.4e-05 22.7 0.0 5.1 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 RLN21179.1 - 7.3e-16 56.7 0.7 0.00046 19.9 0.0 5.1 5 0 0 5 5 5 4 EF-hand domain SHR-BD PF06650.12 RLN21179.1 - 3.4e-15 56.2 0.0 1.1e-13 51.2 0.0 3.3 3 1 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 EF-hand_5 PF13202.6 RLN21179.1 - 2.5e-08 33.0 13.5 0.02 14.4 0.1 4.9 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 RLN21179.1 - 1.1e-06 28.4 5.7 0.097 12.5 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain pair Apt1 PF10351.9 RLN21179.1 - 0.0017 17.3 3.9 0.0028 16.6 0.0 2.6 2 0 0 2 2 2 1 Golgi-body localisation protein domain EF-hand_4 PF12763.7 RLN21179.1 - 0.0033 17.3 0.1 1.8 8.6 0.1 3.0 2 1 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RLN21179.1 - 0.43 10.9 2.5 2.1 8.7 0.1 3.1 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region MerR-DNA-bind PF09278.11 RLN21179.1 - 9.9 6.8 7.0 0.78 10.3 1.2 2.3 2 0 0 2 2 2 0 MerR, DNA binding CSRNP_N PF16019.5 RLN21181.1 - 0.0021 18.0 0.6 0.0023 17.9 0.6 1.1 1 0 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus DUF749 PF05370.11 RLN21181.1 - 0.12 12.4 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF749) Dimer_Tnp_hAT PF05699.14 RLN21182.1 - 1.5e-06 27.9 0.0 1.3e-05 24.9 0.0 2.4 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4246 PF14033.6 RLN21183.1 - 2.1e-106 356.8 4.5 3.9e-104 349.3 0.0 3.0 2 2 0 2 2 2 2 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 RLN21183.1 - 0.033 14.6 0.0 0.074 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase GCIP PF13324.6 RLN21183.1 - 0.16 11.5 2.0 0.42 10.2 2.0 1.7 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting VPS13 PF16908.5 RLN21185.1 - 8.9e-47 159.9 0.0 4.3e-45 154.4 0.0 3.4 4 1 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 RLN21185.1 - 7.4e-24 84.1 0.1 3.1e-23 82.1 0.0 2.2 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 RLN21185.1 - 3.6e-11 43.0 0.0 0.00021 20.8 0.1 6.2 5 1 0 5 5 5 3 Repeating coiled region of VPS13 Ribosomal_L3 PF00297.22 RLN21189.1 - 2.6e-17 62.9 4.6 5.2e-15 55.3 1.1 2.4 2 1 1 3 3 3 2 Ribosomal protein L3 PXA PF02194.15 RLN21190.1 - 2.5e-24 86.2 0.0 5.9e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 RLN21190.1 - 1.1e-14 55.0 0.0 4.5e-14 53.0 0.0 2.1 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 RLN21190.1 - 1e-06 28.7 0.0 4e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 PX domain RUN PF02759.19 RLN21190.1 - 0.0061 16.5 0.0 0.017 15.1 0.0 1.8 1 0 0 1 1 1 1 RUN domain FYVE_2 PF02318.16 RLN21190.1 - 0.028 14.6 3.3 0.094 12.9 3.3 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 RLN21190.1 - 0.16 12.1 10.2 0.018 15.2 5.3 2.0 2 0 0 2 2 2 0 FYVE zinc finger DUF3318 PF11780.8 RLN21190.1 - 5.4 7.0 5.9 15 5.6 5.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) cNMP_binding PF00027.29 RLN21191.1 - 6.2e-25 87.1 0.0 4.9e-10 39.4 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN21191.1 - 1.9e-06 27.3 9.1 4e-06 26.2 9.1 1.5 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RLN21191.1 - 6.3e-05 22.9 3.6 6.3e-05 22.9 3.6 3.1 3 0 0 3 3 3 1 Ion channel PH_4 PF15404.6 RLN21193.1 - 0.33 10.7 0.0 0.33 10.7 0.0 2.5 3 0 0 3 3 3 0 Pleckstrin homology domain DUF2462 PF09495.10 RLN21193.1 - 8.5 7.2 21.5 0.14 12.9 5.8 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2462) Fumble PF03630.14 RLN21194.1 - 3.6e-112 374.8 0.0 2.8e-110 368.6 0.0 2.1 1 1 0 1 1 1 1 Fumble VGLL4 PF15245.6 RLN21195.1 - 0.0079 16.3 1.1 0.0088 16.1 1.1 1.1 1 0 0 1 1 1 1 Transcription cofactor vestigial-like protein 4 SR-25 PF10500.9 RLN21196.1 - 0.0022 17.6 11.6 0.0022 17.6 11.6 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Sugar_tr PF00083.24 RLN21197.1 - 1.1e-106 357.5 18.2 1.2e-106 357.3 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN21197.1 - 7.1e-28 97.5 22.1 2.1e-20 73.0 3.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily bZIP_2 PF07716.15 RLN21198.1 - 0.0057 16.7 2.9 0.015 15.4 2.9 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 RLN21198.1 - 0.21 11.7 1.3 0.41 10.8 1.3 1.4 1 0 0 1 1 1 0 bZIP transcription factor Sugar_tr PF00083.24 RLN21199.1 - 7.4e-102 341.5 23.5 8.4e-102 341.3 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN21199.1 - 1.7e-25 89.7 30.4 2.7e-17 62.7 11.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Caps_synth_CapC PF14102.6 RLN21199.1 - 5.8 7.4 11.2 0.13 12.7 0.8 3.3 3 1 0 3 3 3 0 Capsule biosynthesis CapC DUF2235 PF09994.9 RLN21200.1 - 0.00044 19.7 0.0 0.0007 19.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Palm_thioest PF02089.15 RLN21200.1 - 0.00065 19.6 0.1 0.0014 18.5 0.0 1.6 2 0 0 2 2 2 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 RLN21200.1 - 0.0021 17.7 0.5 0.077 12.6 0.1 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN21200.1 - 0.0057 17.3 0.1 0.0097 16.5 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 RLN21200.1 - 0.013 15.1 0.1 0.061 12.8 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 RLN21200.1 - 0.03 14.0 0.4 0.095 12.4 0.4 1.8 1 1 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 RLN21200.1 - 0.037 13.5 0.1 0.3 10.5 0.0 2.4 3 0 0 3 3 3 0 Putative serine esterase (DUF676) DUF915 PF06028.11 RLN21200.1 - 0.043 13.2 0.0 3.6 6.9 0.0 2.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 RLN21200.1 - 0.088 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 RLN21201.1 - 0.0008 19.1 0.1 0.086 12.5 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 RLN21201.1 - 0.0023 17.8 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 RLN21201.1 - 0.0032 17.0 0.0 0.17 11.4 0.0 2.8 3 0 0 3 3 3 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 RLN21201.1 - 0.009 16.6 0.2 0.026 15.1 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2235 PF09994.9 RLN21201.1 - 0.046 13.1 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF900 PF05990.12 RLN21201.1 - 0.056 12.9 0.0 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 RLN21201.1 - 0.076 12.7 1.9 0.2 11.4 0.7 2.3 2 1 0 2 2 2 0 PGAP1-like protein DUF915 PF06028.11 RLN21201.1 - 0.087 12.1 0.0 0.96 8.7 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Questin_oxidase PF14027.6 RLN21238.1 - 2.3e-27 96.5 0.1 2.7e-27 96.2 0.1 1.1 1 0 0 1 1 1 1 Questin oxidase-like Glucan_synthase PF02364.15 RLN21239.1 - 2.2e-184 615.0 15.5 9e-163 543.5 9.7 3.1 1 1 1 2 2 2 2 1,3-beta-glucan synthase component PNISR PF15996.5 RLN21239.1 - 0.091 13.0 2.4 0.18 12.0 2.4 1.4 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SAPS PF04499.15 RLN21240.1 - 9.2e-08 31.3 0.0 2.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein TruD PF01142.18 RLN21244.1 - 3.3e-58 197.5 0.0 1.4e-54 185.5 0.0 3.5 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Styelin PF17562.2 RLN21244.1 - 0.026 14.9 0.2 0.069 13.5 0.2 1.7 1 0 0 1 1 1 0 Styelin tRNA-synt_2d PF01409.20 RLN21245.1 - 1e-84 283.9 0.1 1.4e-84 283.4 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 RLN21245.1 - 6.2e-19 68.0 0.3 1.6e-18 66.8 0.1 1.9 2 0 0 2 2 2 1 PheRS DNA binding domain 3 PheRS_DBD1 PF18552.1 RLN21245.1 - 2.5e-09 36.7 0.2 1.1e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 PheRS DNA binding domain 1 tRNA_synthFbeta PF17759.1 RLN21245.1 - 1.2e-07 31.4 0.0 1.4e-06 27.9 0.0 2.4 1 1 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 RLN21245.1 - 5.4e-05 22.4 0.0 0.00016 20.9 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 RLN21245.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) GerPE PF10970.8 RLN21245.1 - 0.15 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Spore germination protein GerPE Mito_carr PF00153.27 RLN21246.1 - 1.6e-37 127.3 5.1 5.1e-17 61.6 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Form-deh_trans PF09163.11 RLN21246.1 - 1.8 8.4 4.2 1.3 8.8 0.3 2.3 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane TPR_1 PF00515.28 RLN21247.1 - 1.2e-52 173.7 7.7 3.1e-07 29.9 0.0 10.2 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_2 PF07719.17 RLN21247.1 - 5.5e-47 154.1 5.2 0.00016 21.6 0.0 10.2 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 RLN21247.1 - 2e-40 133.6 5.3 2.7e-05 24.0 0.0 10.1 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_17 PF13431.6 RLN21247.1 - 2.4e-27 93.3 11.6 0.0004 20.6 0.0 9.6 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 RLN21247.1 - 2.6e-24 84.6 11.1 4.2e-06 26.4 0.0 10.2 6 3 4 10 10 10 5 TPR repeat TPR_19 PF14559.6 RLN21247.1 - 6.8e-23 81.0 1.0 3.6e-06 27.4 0.0 6.0 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 RLN21247.1 - 1.9e-22 79.4 7.1 0.00048 20.4 0.1 7.3 4 3 2 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 RLN21247.1 - 6.7e-22 76.3 0.9 0.013 16.2 0.0 8.9 4 2 5 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 RLN21247.1 - 5e-19 68.7 0.3 0.014 16.1 0.0 6.8 2 2 7 9 9 9 7 Tetratricopeptide repeat TPR_6 PF13174.6 RLN21247.1 - 1.3e-17 63.2 2.4 0.56 11.0 0.0 9.1 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN21247.1 - 5.1e-14 51.2 6.6 0.045 13.8 0.0 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN21247.1 - 2.5e-11 43.5 3.2 0.014 15.5 0.3 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN21247.1 - 3.5e-11 43.1 7.4 0.0016 18.6 2.2 3.7 2 2 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 RLN21247.1 - 2.1e-07 30.5 2.9 0.046 12.9 0.1 3.8 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 RLN21247.1 - 3.5e-07 30.1 1.6 0.017 14.8 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat-like domain SNAP PF14938.6 RLN21247.1 - 0.00023 20.7 6.6 1.3 8.4 0.0 4.6 2 2 2 4 4 4 1 Soluble NSF attachment protein, SNAP ChAPs PF09295.10 RLN21247.1 - 0.00045 19.4 0.4 0.0094 15.0 0.0 2.6 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 RLN21247.1 - 0.0088 16.4 0.0 3.8 7.9 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF1965 PF09248.10 RLN21247.1 - 0.015 15.0 0.2 0.56 10.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1965) BTAD PF03704.17 RLN21247.1 - 0.022 15.2 0.9 2.3 8.7 0.0 3.4 3 1 0 3 3 3 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 RLN21247.1 - 0.028 14.5 0.0 26 5.0 0.0 3.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.8 RLN21247.1 - 0.07 12.0 1.1 11 4.8 0.0 3.1 2 1 2 4 4 4 0 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 RLN21247.1 - 0.13 12.2 7.3 8 6.5 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat MIT PF04212.18 RLN21247.1 - 0.58 10.3 5.5 7.2 6.8 0.1 4.4 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Brix PF04427.18 RLN21248.1 - 7.6e-44 150.1 0.1 1.4e-43 149.3 0.1 1.4 1 0 0 1 1 1 1 Brix domain Asp-B-Hydro_N PF05279.11 RLN21248.1 - 0.71 9.9 20.9 1.1 9.3 20.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AP-5_subunit_s1 PF15001.6 RLN21248.1 - 1.3 9.0 7.0 3 7.8 7.0 1.5 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 DUF5308 PF17233.2 RLN21248.1 - 3.6 7.8 8.2 7.9 6.7 8.2 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5308) FAM60A PF15396.6 RLN21248.1 - 5.2 7.0 9.1 8.9 6.3 9.1 1.4 1 0 0 1 1 1 0 Protein Family FAM60A MNNL PF07657.13 RLN21249.1 - 0.23 11.5 5.3 0.52 10.4 5.3 1.5 1 0 0 1 1 1 0 N terminus of Notch ligand OmpH PF03938.14 RLN21249.1 - 0.75 10.1 3.3 0.59 10.5 1.0 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Elicitin PF00964.17 RLN21250.1 - 6.1e-08 32.7 0.4 1.3e-07 31.6 0.4 1.6 1 0 0 1 1 1 1 Elicitin Elicitin PF00964.17 RLN21251.1 - 1.6e-07 31.3 0.3 4.7e-07 29.8 0.2 1.9 1 1 0 1 1 1 1 Elicitin Elicitin PF00964.17 RLN21252.1 - 1.4e-06 28.3 1.1 1.4e-06 28.3 1.1 2.4 1 1 2 3 3 3 1 Elicitin Elicitin PF00964.17 RLN21253.1 - 4.1e-08 33.2 0.2 9.1e-08 32.1 0.1 1.6 1 1 0 1 1 1 1 Elicitin Pkinase_Tyr PF07714.17 RLN21254.1 - 6.6e-14 51.8 0.0 9.9e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN21254.1 - 2.7e-11 43.4 0.0 4.8e-11 42.5 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain DUF4690 PF15756.5 RLN21254.1 - 0.0025 18.4 0.4 0.0063 17.1 0.4 1.7 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Utp14 PF04615.13 RLN21255.1 - 1.8e-159 532.8 66.9 1.8e-159 532.8 66.9 2.1 1 1 0 2 2 2 1 Utp14 protein Ribosomal_60s PF00428.19 RLN21256.1 - 3.1e-21 75.8 5.8 3.5e-21 75.6 5.8 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 RLN21256.1 - 0.0022 18.3 0.0 0.0032 17.8 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain Ribosomal_L22e PF01776.17 RLN21257.1 - 2.3e-45 153.5 0.2 2.9e-45 153.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family ADP_PFK_GK PF04587.15 RLN21257.1 - 0.021 13.4 0.0 0.022 13.3 0.0 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Pkinase PF00069.25 RLN21258.1 - 1.2e-61 208.4 0.0 1.6e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PH_3 PF14593.6 RLN21258.1 - 3.7e-33 113.7 0.1 3.7e-33 113.7 0.1 1.6 2 0 0 2 2 2 1 PH domain Pkinase_Tyr PF07714.17 RLN21258.1 - 9.1e-30 103.8 0.0 1.3e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN21258.1 - 2e-05 24.0 0.0 3.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RLN21258.1 - 0.00046 19.1 0.0 0.0007 18.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN21258.1 - 0.0017 18.4 0.0 0.0049 16.8 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN21258.1 - 0.0047 16.3 0.0 0.0077 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RLN21258.1 - 0.029 13.3 0.2 0.05 12.5 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain ECH_1 PF00378.20 RLN21259.1 - 1.7e-16 60.3 0.0 2.2e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RLN21259.1 - 4.2e-11 42.9 0.0 8.9e-11 41.9 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase TruD PF01142.18 RLN21260.1 - 3.7e-75 253.3 0.0 2.9e-71 240.5 0.0 3.5 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Cytadhesin_P30 PF07271.11 RLN21260.1 - 0.1 12.1 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 R3H PF01424.22 RLN21260.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 R3H domain AAA_23 PF13476.6 RLN21261.1 - 5.8e-31 108.6 0.2 5.8e-31 108.6 0.2 8.2 2 1 2 4 4 2 1 AAA domain SMC_N PF02463.19 RLN21261.1 - 1.1e-06 28.2 0.0 1.1e-06 28.2 0.0 2.8 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RLN21261.1 - 8.5e-06 25.8 0.1 0.00072 19.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Rad50_zn_hook PF04423.14 RLN21261.1 - 9e-06 25.4 0.6 9e-06 25.4 0.6 3.8 2 0 0 2 2 2 1 Rad50 zinc hook motif SbcCD_C PF13558.6 RLN21261.1 - 0.00034 20.8 0.0 0.001 19.2 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit P35 PF02331.15 RLN21261.1 - 0.0088 15.4 0.8 0.04 13.3 0.1 2.2 1 1 1 2 2 2 1 Apoptosis preventing protein ABC_tran PF00005.27 RLN21261.1 - 0.04 14.4 0.0 0.04 14.4 0.0 6.6 3 2 1 4 4 3 0 ABC transporter HK97-gp10_like PF04883.12 RLN21261.1 - 0.23 12.5 10.0 0.061 14.3 2.9 3.8 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component AAA_16 PF13191.6 RLN21261.1 - 0.64 10.4 0.0 0.64 10.4 0.0 5.0 4 2 0 4 4 2 0 AAA ATPase domain AAA_19 PF13245.6 RLN21261.1 - 4.9 7.5 7.6 5.6 7.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain adh_short PF00106.25 RLN21261.1 - 8.5 5.8 12.5 0.054 12.9 1.3 3.0 3 0 0 3 3 3 0 short chain dehydrogenase TAXi_C PF14541.6 RLN21262.1 - 0.024 14.4 0.0 0.063 13.0 0.0 1.7 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Ras PF00071.22 RLN21263.1 - 8.6e-35 119.7 0.0 1.2e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN21263.1 - 1.9e-25 89.4 0.0 3e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN21263.1 - 2e-09 37.1 0.0 2.7e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RLN21263.1 - 0.00086 18.7 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Glyco_hydro_3 PF00933.21 RLN21265.1 - 1.3e-50 172.6 0.0 1.9e-50 172.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN21265.1 - 4.3e-36 124.8 0.1 7.8e-36 123.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RLN21265.1 - 2.8e-13 49.8 0.5 8.6e-13 48.2 0.2 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain Lipocalin_2 PF08212.12 RLN21273.1 - 0.05 13.5 0.3 0.16 11.9 0.3 1.7 1 1 0 1 1 1 0 Lipocalin-like domain Macoilin PF09726.9 RLN21273.1 - 0.37 9.3 9.1 0.4 9.2 9.1 1.0 1 0 0 1 1 1 0 Macoilin family CTD_bind PF04818.13 RLN21274.1 - 0.00062 20.5 0.3 0.027 15.3 0.1 2.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Phage_antitermQ PF06530.12 RLN21274.1 - 0.041 13.8 0.2 0.59 10.0 0.0 2.4 2 0 0 2 2 2 0 Phage antitermination protein Q B2-adapt-app_C PF09066.10 RLN21275.1 - 2.7e-07 30.6 0.0 9.1e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 Beta2-adaptin appendage, C-terminal sub-domain Tyrosinase PF00264.20 RLN21276.1 - 0.00032 21.0 0.7 0.0006 20.2 0.2 1.6 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyrosinase PF00264.20 RLN21277.1 - 4.7e-12 46.7 0.0 5.9e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF5363 PF17320.2 RLN21277.1 - 0.18 11.7 1.5 0.24 11.3 0.3 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5363) DUF1126 PF06565.12 RLN21278.1 - 7e-79 260.4 0.0 6.9e-28 96.5 0.0 3.4 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 RLN21278.1 - 0.0053 17.2 0.4 0.37 11.3 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN21278.1 - 0.016 15.1 0.0 0.69 10.0 0.0 3.0 2 0 0 2 2 2 0 EF-hand domain Nop PF01798.18 RLN21279.1 - 1.4e-88 296.3 0.2 1.4e-88 296.3 0.2 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 RLN21279.1 - 2.9e-17 62.8 0.3 2.9e-17 62.8 0.3 2.7 3 0 0 3 3 3 1 NOP5NT (NUC127) domain Alg6_Alg8 PF03155.15 RLN21280.1 - 9.5e-90 301.9 14.6 1.9e-82 277.8 8.3 2.1 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family DNA_pol_B_palm PF14792.6 RLN21282.1 - 0.021 15.0 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase beta palm adh_short_C2 PF13561.6 RLN21283.1 - 7.7e-17 61.6 0.1 2.6e-16 59.9 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RLN21283.1 - 1.6e-16 60.4 0.2 2.6e-16 59.7 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase HMA PF00403.26 RLN21284.1 - 1.5e-69 230.3 31.5 1.4e-14 54.2 0.4 8.6 9 0 0 9 9 9 6 Heavy-metal-associated domain Hydrolase PF00702.26 RLN21284.1 - 1.6e-47 162.5 0.2 3e-47 161.6 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RLN21284.1 - 3.8e-44 150.4 4.7 5e-44 150.0 1.4 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RLN21284.1 - 1.3e-05 25.1 0.5 0.0098 15.7 0.3 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase DUF1636 PF07845.11 RLN21284.1 - 0.077 13.4 3.7 35 4.9 0.0 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF1636) AlbA_2 PF04326.14 RLN21284.1 - 0.14 12.5 0.0 1.6 9.1 0.0 2.3 2 0 0 2 2 2 0 Putative DNA-binding domain PseudoU_synth_2 PF00849.22 RLN21285.1 - 2.3e-10 40.8 0.0 2.8e-08 34.0 0.0 2.5 1 1 1 2 2 2 2 RNA pseudouridylate synthase S4 PF01479.25 RLN21285.1 - 0.082 12.6 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 S4 domain CN_hydrolase PF00795.22 RLN21286.1 - 3.4e-67 226.5 0.0 3.9e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PAP_fibrillin PF04755.12 RLN21287.1 - 0.016 15.1 0.1 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 PAP_fibrillin DUF4471 PF14740.6 RLN21287.1 - 0.13 11.5 1.9 0.19 11.0 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Vfa1 PF08432.10 RLN21287.1 - 0.87 9.9 9.9 1.9 8.8 9.9 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DNA_pol_phi PF04931.13 RLN21287.1 - 4.3 5.3 23.0 6 4.8 23.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Exo_endo_phos_2 PF14529.6 RLN21306.1 - 9.8e-05 22.2 0.0 0.00024 20.9 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RLN21306.1 - 0.0011 18.6 0.0 0.0028 17.2 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PseudoU_synth_2 PF00849.22 RLN21307.1 - 2.3e-05 24.5 0.0 4.9e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 RLN21307.1 - 0.00068 19.3 0.1 0.0017 18.1 0.1 1.7 1 0 0 1 1 1 1 S4 domain DUF4027 PF13219.6 RLN21309.1 - 1.9 8.4 4.5 4 7.4 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) DUF1180 PF06679.12 RLN21309.1 - 2.1 8.8 7.9 0.52 10.7 0.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) C2 PF00168.30 RLN21310.1 - 4.3e-75 248.6 0.4 2e-12 47.3 0.0 8.6 7 1 1 8 8 8 8 C2 domain FerI PF08151.12 RLN21310.1 - 0.00021 21.3 0.9 0.00072 19.6 0.4 2.3 2 0 0 2 2 2 1 FerI (NUC094) domain NT-C2 PF10358.9 RLN21310.1 - 0.0027 17.4 0.6 0.028 14.2 0.0 2.6 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins U3_snoRNA_assoc PF08297.11 RLN21310.1 - 0.13 13.0 2.3 2.6 8.8 1.3 2.8 2 0 0 2 2 2 0 U3 snoRNA associated IFT57 PF10498.9 RLN21310.1 - 2.5 7.0 5.7 5 6.0 5.7 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 ADH_zinc_N_2 PF13602.6 RLN21311.1 - 4.7e-24 85.9 0.1 1.1e-23 84.8 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 RLN21311.1 - 1.2e-15 57.7 0.7 3.1e-15 56.3 0.6 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN21311.1 - 1.4e-09 37.8 0.0 2.5e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF2855 PF11017.8 RLN21311.1 - 0.0021 17.9 0.2 0.0039 17.0 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2855) TrkA_N PF02254.18 RLN21311.1 - 0.015 15.6 0.2 0.03 14.6 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 RLN21311.1 - 0.044 13.1 0.3 0.069 12.4 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CbiJ PF02571.14 RLN21311.1 - 0.089 12.2 0.1 1.4 8.3 0.1 2.1 2 0 0 2 2 2 0 Precorrin-6x reductase CbiJ/CobK ADH_zinc_N_2 PF13602.6 RLN21312.1 - 2.9e-23 83.4 0.1 6.3e-23 82.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 RLN21312.1 - 6.2e-15 55.3 0.6 1.4e-14 54.2 0.5 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN21312.1 - 6e-09 35.8 0.0 1.2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF2855 PF11017.8 RLN21312.1 - 0.0096 15.7 0.1 0.013 15.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) TrkA_N PF02254.18 RLN21312.1 - 0.084 13.1 0.2 0.16 12.3 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain ADH_zinc_N_2 PF13602.6 RLN21313.1 - 6.2e-22 79.1 0.0 1.4e-21 78.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN21313.1 - 7.1e-09 35.5 0.0 6.4e-08 32.4 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN21313.1 - 1.5e-08 34.7 0.6 3.4e-08 33.5 0.6 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 RLN21313.1 - 0.078 12.3 0.5 0.14 11.4 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF4201 PF13870.6 RLN21401.1 - 8.1e-39 133.2 31.0 8.1e-39 133.2 31.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4201) YabA PF06156.13 RLN21401.1 - 0.18 12.5 28.1 0.15 12.7 4.2 4.2 2 1 2 4 4 4 0 Initiation control protein YabA Sporozoite_P67 PF05642.11 RLN21401.1 - 0.8 7.7 3.9 1.3 7.0 3.9 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF812 PF05667.11 RLN21401.1 - 0.97 8.2 36.8 0.23 10.3 23.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Nuc_sug_transp PF04142.15 RLN21402.1 - 6.7e-43 147.0 9.7 1.7e-42 145.8 9.7 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 RLN21402.1 - 2.4e-05 24.5 9.2 2.4e-05 24.5 9.2 2.5 2 1 0 2 2 2 1 EamA-like transporter family Orai-1 PF07856.12 RLN21402.1 - 0.0092 15.7 1.9 0.038 13.7 1.9 2.0 1 1 0 1 1 1 1 Mediator of CRAC channel activity zf-RanBP PF00641.18 RLN21412.1 - 5.9e-05 22.3 4.2 9.9e-05 21.6 4.2 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 RLN21412.1 - 0.017 14.5 3.0 0.04 13.3 3.0 1.7 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DcuC PF03606.15 RLN21412.1 - 0.15 10.4 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier ArfGap PF01412.18 RLN21413.1 - 2.7e-06 27.5 0.6 2.7e-06 27.5 0.6 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf CDC45 PF02724.14 RLN21413.1 - 0.0059 15.0 0.1 0.0062 14.9 0.1 1.3 1 0 0 1 1 1 1 CDC45-like protein DivIC PF04977.15 RLN21414.1 - 0.73 9.6 3.6 3.9 7.3 1.1 2.5 2 0 0 2 2 2 0 Septum formation initiator WD40 PF00400.32 RLN21415.1 - 5.7e-21 74.4 10.4 8.2e-05 23.3 0.2 9.2 8 0 0 8 8 8 4 WD domain, G-beta repeat EF-hand_1 PF00036.32 RLN21415.1 - 1.2e-19 68.3 14.5 0.00094 18.6 0.6 5.8 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 RLN21415.1 - 2.5e-19 67.5 12.6 7.7e-05 22.3 1.1 5.8 5 0 0 5 5 5 5 EF-hand domain EF-hand_7 PF13499.6 RLN21415.1 - 4.7e-18 65.4 13.2 1.2e-06 28.8 0.1 3.7 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 RLN21415.1 - 1.5e-11 43.2 7.0 0.016 14.7 0.0 4.9 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 RLN21415.1 - 1.6e-05 24.7 15.9 0.016 15.0 0.3 5.6 5 1 1 6 6 6 3 EF-hand domain pair ANAPC4_WD40 PF12894.7 RLN21415.1 - 0.034 14.5 0.0 19 5.6 0.0 3.5 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain MCM PF00493.23 RLN21415.1 - 0.11 11.5 0.1 0.5 9.4 0.0 1.9 2 0 0 2 2 2 0 MCM P-loop domain PALP PF00291.25 RLN21416.1 - 3.8e-68 230.1 0.5 4.9e-68 229.7 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IQ PF00612.27 RLN21417.1 - 3e-06 26.6 7.1 0.0081 15.9 0.1 4.4 4 0 0 4 4 4 2 IQ calmodulin-binding motif TruB_C_2 PF16198.5 RLN21418.1 - 8.4e-22 77.1 1.1 1.7e-21 76.1 1.1 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 RLN21418.1 - 4.8e-20 71.3 2.0 4.8e-20 71.3 2.0 2.3 2 1 0 2 2 2 1 PUA domain Coilin_N PF15862.5 RLN21418.1 - 0.00018 21.3 7.0 0.00029 20.7 7.0 1.5 1 0 0 1 1 1 1 Coilin N-terminus FIST_C PF10442.9 RLN21418.1 - 0.14 12.2 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 FIST C domain RR_TM4-6 PF06459.12 RLN21418.1 - 0.16 11.8 17.1 0.19 11.5 17.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.12 RLN21418.1 - 0.35 11.1 8.9 0.45 10.8 8.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF913 PF06025.12 RLN21418.1 - 1.8 7.4 4.6 2.4 7.1 4.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TAF4 PF05236.14 RLN21418.1 - 2.4 7.9 18.1 3.4 7.3 18.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family CDC45 PF02724.14 RLN21418.1 - 2.6 6.3 18.5 3.1 6.0 18.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 RLN21418.1 - 4.5 7.3 35.3 6.7 6.7 35.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 adh_short_C2 PF13561.6 RLN21438.1 - 2.2e-19 70.0 0.4 1.3e-10 41.3 0.1 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RLN21438.1 - 4.9e-17 62.0 0.5 7.5e-16 58.2 0.5 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Cofac_haem_bdg PF04187.13 RLN21439.1 - 0.065 13.2 0.1 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN ApbA PF02558.16 RLN21439.1 - 0.093 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TRIQK PF15168.6 RLN21439.1 - 0.51 10.3 0.0 0.51 10.3 0.0 2.1 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family EF-hand_6 PF13405.6 RLN21440.1 - 1.1e-06 28.1 1.1 0.00049 19.8 0.2 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 RLN21440.1 - 0.0012 18.2 5.4 0.02 14.4 0.1 3.9 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.6 RLN21440.1 - 0.0057 17.1 0.8 0.58 10.6 0.2 3.0 2 1 1 3 3 3 2 EF-hand domain pair Neisseria_TspB PF05616.13 RLN21440.1 - 0.031 12.7 1.0 0.041 12.4 1.0 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein EF-hand_8 PF13833.6 RLN21440.1 - 0.041 13.7 5.4 0.66 9.9 0.1 3.3 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.6 RLN21440.1 - 0.16 11.5 0.3 3 7.5 0.0 2.6 2 0 0 2 2 2 0 EF hand Peptidase_U4 PF03419.13 RLN21441.1 - 0.026 13.8 1.3 0.042 13.1 1.3 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA EF-hand_6 PF13405.6 RLN21442.1 - 1.1e-06 28.1 0.8 0.0019 18.0 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 RLN21442.1 - 2.1e-05 23.8 0.0 0.024 14.2 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RLN21442.1 - 0.00099 19.5 0.2 0.064 13.7 0.1 2.8 2 1 0 2 2 2 1 EF-hand domain pair Beta-lactamase2 PF13354.6 RLN21443.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase enzyme family adh_short_C2 PF13561.6 RLN21444.1 - 2.8e-50 171.1 1.1 3.4e-50 170.8 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RLN21444.1 - 1.4e-42 145.4 0.5 1.8e-42 145.0 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RLN21444.1 - 6.5e-08 32.7 0.3 1.1e-07 31.9 0.3 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 RLN21444.1 - 0.00059 19.1 0.1 0.0011 18.2 0.1 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 RLN21444.1 - 0.00059 19.8 0.3 0.00086 19.2 0.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 RLN21444.1 - 0.006 16.8 0.2 0.011 16.0 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 RLN21444.1 - 0.014 14.9 0.1 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 RLN21444.1 - 0.05 13.0 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 RLN21444.1 - 0.061 13.0 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 RLN21444.1 - 0.093 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.6 RLN21445.1 - 4.8e-09 36.1 0.2 5.2e-09 36.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Na_H_antiport_3 PF07399.11 RLN21445.1 - 0.13 11.1 0.5 0.14 11.0 0.5 1.0 1 0 0 1 1 1 0 Putative Na+/H+ antiporter Noc2 PF03715.13 RLN21450.1 - 1.2e-82 277.6 0.2 5e-82 275.5 0.0 2.1 2 1 1 3 3 3 1 Noc2p family Nop14 PF04147.12 RLN21450.1 - 0.036 12.3 0.0 0.036 12.3 0.0 4.5 2 2 1 3 3 3 0 Nop14-like family Pkinase PF00069.25 RLN21451.1 - 3.2e-69 233.3 0.0 3.9e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN21451.1 - 5.5e-27 94.7 0.0 7.3e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN21451.1 - 0.00011 22.3 3.7 0.043 13.7 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 RLN21451.1 - 0.00028 20.3 0.1 0.00058 19.3 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN21451.1 - 0.00029 20.3 0.1 0.31 10.3 0.0 2.1 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 RLN21451.1 - 0.0071 16.0 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 RLN21451.1 - 0.013 14.3 0.0 0.095 11.5 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase ABC2_membrane PF01061.24 RLN21452.1 - 9.5e-34 116.7 44.9 2e-33 115.6 29.6 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN21452.1 - 1.1e-16 61.6 0.1 1.6e-16 61.1 0.1 1.2 1 0 0 1 1 1 1 ABC transporter PDR_CDR PF06422.12 RLN21452.1 - 2.1e-06 27.5 0.1 1.2e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 CDR ABC transporter SMC_N PF02463.19 RLN21452.1 - 0.00024 20.6 0.0 0.00046 19.7 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RLN21452.1 - 0.00036 20.4 0.1 0.43 10.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN21452.1 - 0.00084 19.0 0.4 0.0045 16.7 0.5 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN21452.1 - 0.0051 16.7 0.2 0.01 15.7 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 RLN21452.1 - 0.027 14.9 0.0 0.049 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 RLN21452.1 - 0.062 13.8 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RLN21452.1 - 0.09 12.3 0.5 0.21 11.1 0.5 1.5 1 0 0 1 1 1 0 AAA domain Cupin_4 PF08007.12 RLN21453.1 - 5.2e-10 39.3 0.0 9.3e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.22 RLN21453.1 - 0.044 13.4 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 Cupin Arm PF00514.23 RLN21484.1 - 5.1e-39 131.1 8.7 9.5e-05 22.3 0.0 11.2 11 0 0 11 11 11 8 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN21484.1 - 1.5e-07 31.0 11.3 28 5.3 0.0 8.9 9 0 0 9 9 9 0 HEAT repeat Arm_2 PF04826.13 RLN21484.1 - 2.1e-06 27.4 0.0 0.035 13.6 0.0 4.3 3 1 0 4 4 4 1 Armadillo-like TM1506 PF08973.10 RLN21484.1 - 9.1e-06 25.4 0.1 12 5.6 0.0 6.4 4 3 4 8 8 8 2 Domain of unknown function (DUF1893) HEAT_EZ PF13513.6 RLN21484.1 - 2.1e-05 24.9 18.0 0.066 13.7 0.1 6.1 7 0 0 7 7 7 2 HEAT-like repeat Atx10homo_assoc PF09759.9 RLN21484.1 - 5.1e-05 23.2 2.0 1.6 8.8 0.1 4.6 2 2 3 5 5 5 2 Spinocerebellar ataxia type 10 protein domain Nuc_N PF14448.6 RLN21484.1 - 0.00016 21.4 5.0 66 3.5 0.0 7.3 8 0 0 8 8 8 0 Nuclease N terminal DUF3437 PF11919.8 RLN21484.1 - 0.0011 18.8 0.2 8.6 6.4 0.0 5.0 4 2 2 6 6 6 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.6 RLN21484.1 - 0.031 14.7 29.9 0.3 11.5 1.8 5.0 1 1 3 5 5 5 0 HEAT repeats PACT_coil_coil PF10495.9 RLN21484.1 - 0.044 14.3 0.0 52 4.5 0.0 3.7 2 1 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein ABM PF03992.16 RLN21520.1 - 0.0043 17.1 0.1 0.0058 16.7 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF4718 PF15842.5 RLN21520.1 - 0.11 12.3 0.1 0.14 11.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) ABM PF03992.16 RLN21522.1 - 5.7e-06 26.4 0.1 8e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DNA_pol_B_exo1 PF03104.19 RLN21522.1 - 0.031 13.4 0.2 0.033 13.3 0.2 1.0 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain Pkinase PF00069.25 RLN21523.1 - 2.2e-10 40.4 0.0 3.7e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN21523.1 - 0.023 14.0 0.0 0.046 13.0 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase DUF3357 PF11837.8 RLN21524.1 - 0.083 13.4 0.1 0.2 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Piwi PF02171.17 RLN21525.1 - 9.5e-92 307.5 0.0 1.6e-91 306.7 0.0 1.4 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 RLN21525.1 - 2.7e-16 59.0 0.0 5.2e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 RLN21525.1 - 4.8e-16 58.8 0.0 8.9e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 RLN21525.1 - 2.6e-15 57.3 0.0 7.7e-15 55.7 0.0 1.9 1 1 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 RLN21525.1 - 2.9e-09 37.1 0.0 7.7e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 RLN21525.1 - 4e-09 36.6 0.1 1.6e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 Mid domain of argonaute GRP PF07172.11 RLN21525.1 - 2 9.1 27.0 6.3 7.6 27.0 1.8 1 0 0 1 1 1 0 Glycine rich protein family RAI16-like PF10257.9 RLN21568.1 - 5.2e-40 137.4 0.7 8.7e-40 136.7 0.7 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DUF3246 PF11596.8 RLN21568.1 - 0.031 13.7 1.8 0.072 12.5 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) B12-binding_2 PF02607.17 RLN21568.1 - 0.11 12.9 0.1 36 4.9 0.0 3.6 4 0 0 4 4 4 0 B12 binding domain MCD_N PF17408.2 RLN21568.1 - 0.19 11.9 1.5 0.27 11.4 0.1 2.1 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain Sporozoite_P67 PF05642.11 RLN21568.1 - 1.5 6.8 4.8 2.4 6.1 4.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1993 PF09351.10 RLN21568.1 - 2.6 8.2 6.4 0.7 10.0 0.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1993) C2 PF00168.30 RLN21569.1 - 7.9e-05 22.9 0.0 0.0002 21.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain IQ PF00612.27 RLN21569.1 - 8.3e-05 22.1 29.1 0.031 14.1 0.8 6.9 6 0 0 6 6 6 4 IQ calmodulin-binding motif Transket_pyr PF02779.24 RLN21570.1 - 6.4e-45 153.0 0.0 9.4e-45 152.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 RLN21570.1 - 2.5e-42 143.7 0.2 6.9e-42 142.2 0.1 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 RLN21570.1 - 6.4e-05 23.2 0.0 0.00022 21.5 0.0 1.9 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II ADH_N PF08240.12 RLN21572.1 - 2.4e-19 69.2 0.7 2.4e-19 69.2 0.7 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN21572.1 - 1.2e-07 31.8 0.1 4.2e-06 26.8 0.1 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN21572.1 - 0.029 13.7 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N_assoc PF13823.6 RLN21572.1 - 0.049 13.6 3.6 0.47 10.4 2.9 2.6 2 1 0 2 2 2 0 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.6 RLN21572.1 - 0.13 13.4 0.0 0.29 12.2 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Arm PF00514.23 RLN21585.1 - 2e-35 119.7 13.8 8.1e-09 35.2 0.0 9.2 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN21585.1 - 4.1e-19 67.0 5.2 0.064 13.5 0.1 8.2 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 RLN21585.1 - 9e-16 58.0 10.4 0.0024 18.2 0.0 5.6 2 2 3 6 6 6 5 HEAT repeats HEAT_EZ PF13513.6 RLN21585.1 - 2.1e-13 50.5 15.7 0.00089 19.7 0.1 7.5 7 1 1 8 8 8 5 HEAT-like repeat Cnd1 PF12717.7 RLN21585.1 - 5.2e-13 49.4 1.4 0.014 15.5 0.0 4.8 3 2 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 RLN21585.1 - 2.2e-07 29.9 2.5 0.0047 15.5 0.0 3.3 2 1 1 3 3 3 2 Adaptin N terminal region DNA_alkylation PF08713.11 RLN21585.1 - 2.9e-07 30.4 0.0 0.85 9.3 0.0 3.9 2 1 2 4 4 4 3 DNA alkylation repair enzyme CLASP_N PF12348.8 RLN21585.1 - 1.5e-06 27.9 0.3 0.16 11.5 0.0 3.7 3 1 0 3 3 3 2 CLASP N terminal CHASE6_C PF17150.4 RLN21585.1 - 2.9e-06 27.9 0.5 25 5.6 0.0 6.1 6 0 0 6 6 6 0 C-terminal domain of two-partite extracellular sensor domain Atx10homo_assoc PF09759.9 RLN21585.1 - 0.00097 19.1 0.6 2.5 8.2 0.1 4.3 3 1 2 5 5 5 1 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_C PF11698.8 RLN21585.1 - 0.001 19.2 0.1 11 6.2 0.0 4.3 3 2 2 5 5 5 0 V-ATPase subunit H HEAT_UF PF18817.1 RLN21585.1 - 0.0021 18.3 0.2 0.24 11.7 0.0 3.8 4 0 0 4 4 4 1 Repeat of uncharacterized protein PH0542 Proteasom_PSMB PF10508.9 RLN21585.1 - 0.0027 16.3 5.1 0.016 13.8 0.2 3.3 2 1 1 4 4 4 1 Proteasome non-ATPase 26S subunit Arm_2 PF04826.13 RLN21585.1 - 0.0076 15.7 0.7 12 5.3 0.0 4.2 3 1 1 5 5 5 0 Armadillo-like Mo25 PF08569.11 RLN21585.1 - 0.011 15.1 0.1 0.35 10.2 0.1 2.9 1 1 0 1 1 1 0 Mo25-like Npa1 PF11707.8 RLN21585.1 - 0.018 14.4 0.1 0.79 9.0 0.0 2.6 2 0 0 2 2 2 0 Ribosome 60S biogenesis N-terminal DUF3144 PF11342.8 RLN21585.1 - 0.09 13.1 0.1 11 6.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3144) HEAT_PBS PF03130.16 RLN21585.1 - 0.26 12.1 12.7 16 6.5 0.2 5.7 6 0 0 6 6 5 0 PBS lyase HEAT-like repeat DUF3730 PF12530.8 RLN21585.1 - 0.3 10.6 4.8 1.1 8.8 0.0 3.8 4 2 0 4 4 4 0 Protein of unknown function (DUF3730) UAA PF08449.11 RLN21586.1 - 8.1e-48 163.2 18.1 1.5e-47 162.3 18.1 1.4 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 RLN21586.1 - 1.5e-05 24.5 17.9 2.6e-05 23.7 2.1 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 RLN21586.1 - 0.0021 17.3 5.4 0.0027 16.9 0.2 2.9 2 1 2 4 4 4 1 Nucleotide-sugar transporter EamA PF00892.20 RLN21586.1 - 0.0057 16.8 10.6 0.0057 16.8 10.6 2.3 2 0 0 2 2 2 1 EamA-like transporter family CRT-like PF08627.10 RLN21586.1 - 0.03 13.3 14.8 0.051 12.5 14.0 1.8 1 1 1 2 2 2 0 CRT-like, chloroquine-resistance transporter-like PIRT PF15099.6 RLN21586.1 - 0.081 12.5 0.0 0.081 12.5 0.0 2.5 3 1 0 3 3 3 0 Phosphoinositide-interacting protein family BT1 PF03092.16 RLN21588.1 - 1.2e-13 50.2 10.8 1.2e-10 40.3 0.4 3.1 3 0 0 3 3 3 3 BT1 family FHA PF00498.26 RLN21589.1 - 3.2e-11 43.4 0.0 4.8e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RLN21589.1 - 1.6e-05 25.1 0.1 3.6e-05 24.0 0.0 1.6 1 1 1 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain BBS2_C PF14782.6 RLN21589.1 - 0.035 12.9 0.2 0.041 12.6 0.2 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal DUF745 PF05335.13 RLN21589.1 - 0.055 13.2 2.3 0.12 12.1 1.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF745) OEP PF02321.18 RLN21589.1 - 0.25 11.1 1.6 0.34 10.7 1.6 1.1 1 0 0 1 1 1 0 Outer membrane efflux protein DUF543 PF04418.12 RLN21590.1 - 0.022 14.7 6.3 0.037 14.0 2.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF543) Aldo_ket_red PF00248.21 RLN21591.1 - 2.7e-12 46.5 0.0 3e-12 46.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PGM_PMM_I PF02878.16 RLN21591.1 - 0.08 12.7 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I YEATS PF03366.16 RLN21592.1 - 4.2e-25 87.5 0.0 1e-24 86.3 0.0 1.7 1 1 0 1 1 1 1 YEATS family OspD PF03207.13 RLN21592.1 - 0.021 14.2 0.8 0.029 13.7 0.8 1.1 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) PDCD2_C PF04194.13 RLN21593.1 - 1.3e-33 116.5 1.5 1.8e-33 116.1 0.2 1.8 1 1 1 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain PDGF PF00341.17 RLN21593.1 - 0.024 14.9 0.0 0.064 13.6 0.0 1.7 1 0 0 1 1 1 0 PDGF/VEGF domain DUF4810 PF16068.5 RLN21593.1 - 0.054 14.0 0.2 0.12 13.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4810) PseudoU_synth_2 PF00849.22 RLN21595.1 - 1.3e-15 57.8 0.0 2.6e-15 56.8 0.0 1.5 1 1 0 1 1 1 1 RNA pseudouridylate synthase BT1 PF03092.16 RLN21595.1 - 7.7e-15 54.1 8.9 5.1e-10 38.2 0.1 3.1 3 0 0 3 3 3 3 BT1 family S4 PF01479.25 RLN21595.1 - 1.1e-08 34.7 0.4 3.5e-08 33.0 0.1 2.1 2 0 0 2 2 2 1 S4 domain TruB_N PF01509.18 RLN21595.1 - 0.028 14.8 0.0 0.053 13.9 0.0 1.4 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) Ribosomal_L9_N PF01281.19 RLN21596.1 - 9.5e-19 66.7 0.2 2e-18 65.7 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain DNA_binding_1 PF01035.20 RLN21597.1 - 1.1e-09 38.3 0.0 1.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF908 PF06012.12 RLN21598.1 - 0.009 15.5 0.4 0.009 15.5 0.4 2.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) RAP PF08373.10 RLN21599.1 - 3.9e-07 30.1 0.3 3.6e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 RAP domain Pertus-S5-tox PF09276.10 RLN21599.1 - 0.18 11.9 0.0 0.54 10.3 0.0 1.8 2 1 0 2 2 2 0 Pertussis toxin S5 subunit DUF3712 PF12505.8 RLN21600.1 - 7e-13 48.9 0.2 1.5e-12 47.8 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Fumarate_red_C PF02300.17 RLN21600.1 - 0.029 14.5 0.6 0.06 13.4 0.6 1.5 1 0 0 1 1 1 0 Fumarate reductase subunit C DUF3989 PF13150.6 RLN21600.1 - 0.045 13.5 0.2 0.08 12.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) RhaA PF06134.11 RLN21600.1 - 0.075 12.1 0.0 0.19 10.8 0.0 1.5 1 1 1 2 2 2 0 L-rhamnose isomerase (RhaA) Neurensin PF14927.6 RLN21600.1 - 0.081 12.6 0.3 0.21 11.3 0.2 1.7 2 0 0 2 2 2 0 Neurensin Orf78 PF06024.12 RLN21600.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) DUF3712 PF12505.8 RLN21601.1 - 3.2e-15 56.5 0.1 8.8e-15 55.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Orf78 PF06024.12 RLN21601.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Synaptobrevin PF00957.21 RLN21601.1 - 0.72 9.7 3.7 1.4 8.7 3.7 1.4 1 0 0 1 1 1 0 Synaptobrevin SCIMP PF15050.6 RLN21601.1 - 3.5 8.1 4.7 5.9 7.4 4.7 1.3 1 0 0 1 1 1 0 SCIMP protein DUF4307 PF14155.6 RLN21601.1 - 6.4 6.6 5.4 70 3.3 2.8 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4307) Zip PF02535.22 RLN21605.1 - 1.2e-05 24.7 19.9 2.9e-05 23.5 19.9 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter OB_Dis3 PF17849.1 RLN21606.1 - 4.8e-17 61.7 0.0 1.4e-16 60.3 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 RLN21606.1 - 3.7e-13 49.4 0.0 8e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain Zip PF02535.22 RLN21607.1 - 2.3e-13 50.1 17.0 1e-12 47.9 17.0 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter SepA PF17080.5 RLN21607.1 - 0.1 12.9 0.4 0.1 12.9 0.4 1.7 2 0 0 2 2 2 0 Multidrug Resistance efflux pump ATP-synt_10 PF05176.14 RLN21608.1 - 1.5e-28 99.8 0.0 1.7e-28 99.5 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Kelch_3 PF13415.6 RLN21609.1 - 7.1e-23 80.4 20.0 3.1e-07 30.5 0.1 7.0 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 RLN21609.1 - 9.7e-23 79.9 12.6 0.00036 20.5 0.7 7.2 6 2 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN21609.1 - 6.7e-22 77.0 17.6 6.6e-05 22.8 0.0 6.7 6 1 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RLN21609.1 - 3.2e-21 74.8 15.9 5.7e-07 29.6 0.0 6.6 6 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 RLN21609.1 - 1e-20 73.0 13.7 1.2e-06 28.0 0.0 6.5 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 RLN21609.1 - 6.5e-08 32.2 17.9 3.2e-05 23.7 0.1 6.0 6 3 0 6 6 6 3 Kelch motif FYVE PF01363.21 RLN21610.1 - 1.4e-26 92.4 30.5 2.1e-15 56.6 9.9 3.6 3 0 0 3 3 3 2 FYVE zinc finger DnaJ PF00226.31 RLN21610.1 - 7.3e-10 38.8 0.5 3.7e-09 36.6 0.2 2.5 2 0 0 2 2 2 1 DnaJ domain PX PF00787.24 RLN21610.1 - 1.5e-05 24.9 0.1 4.8e-05 23.3 0.1 1.9 1 0 0 1 1 1 1 PX domain zinc_ribbon_2 PF13240.6 RLN21610.1 - 2.3e-05 24.0 0.8 2.3e-05 24.0 0.8 2.8 2 0 0 2 2 2 1 zinc-ribbon domain FYVE_2 PF02318.16 RLN21610.1 - 0.00078 19.7 3.6 0.00078 19.7 3.6 7.1 8 1 1 9 9 9 2 FYVE-type zinc finger DZR PF12773.7 RLN21610.1 - 0.0022 17.9 0.4 0.0022 17.9 0.4 5.1 3 2 1 4 4 4 1 Double zinc ribbon bZIP_1 PF00170.21 RLN21610.1 - 0.0073 16.4 3.4 0.0073 16.4 3.4 5.9 5 1 1 6 6 6 1 bZIP transcription factor zinc_ribbon_15 PF17032.5 RLN21610.1 - 0.036 14.8 0.4 0.036 14.8 0.4 4.3 3 1 1 4 4 4 0 zinc-ribbon family SHIPPO-rpt PF07004.12 RLN21611.1 - 0.02 15.8 9.9 0.45 11.5 0.1 4.5 3 0 0 3 3 3 0 Sperm-tail PG-rich repeat ETS_PEA3_N PF04621.13 RLN21611.1 - 2 8.2 14.7 0.046 13.6 4.7 2.4 1 1 2 3 3 3 0 PEA3 subfamily ETS-domain transcription factor N terminal domain Dimer_Tnp_hAT PF05699.14 RLN21641.1 - 1.1e-09 37.9 0.0 5.1e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region PPR_2 PF13041.6 RLN21642.1 - 4.3e-13 49.2 7.2 0.099 12.9 0.0 8.6 8 2 1 9 9 9 4 PPR repeat family PPR PF01535.20 RLN21642.1 - 9.8e-09 34.9 8.0 2.4 8.6 0.0 8.8 9 0 0 9 9 9 3 PPR repeat PPR_3 PF13812.6 RLN21642.1 - 0.00089 19.3 6.0 4.4 7.5 0.1 6.4 7 1 1 8 8 8 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 RLN21642.1 - 0.002 17.8 1.0 1.8 8.3 0.0 5.3 6 0 0 6 6 6 1 PPR repeat LAGLIDADG_3 PF14528.6 RLN21642.1 - 0.014 15.6 0.0 0.052 13.9 0.0 1.9 1 0 0 1 1 1 0 LAGLIDADG-like domain RecG_N PF17190.4 RLN21642.1 - 0.02 15.6 1.5 12 6.7 0.4 4.1 3 0 0 3 3 3 0 RecG N-terminal helical domain Pkinase PF00069.25 RLN21645.1 - 4.8e-63 213.0 0.1 7.6e-63 212.3 0.1 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN21645.1 - 5.1e-16 58.7 0.1 8.3e-15 54.8 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN21645.1 - 6e-06 26.4 0.0 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN21645.1 - 0.014 14.2 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 RLN21645.1 - 0.028 13.8 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RLN21645.1 - 0.047 13.3 0.1 0.079 12.5 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2459 PF09601.10 RLN21645.1 - 0.061 13.1 0.0 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) NAD_binding_1 PF00175.21 RLN21647.1 - 1.3e-15 58.0 0.0 2e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 RLN21647.1 - 2.4e-09 37.1 0.1 3.3e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_6 PF08030.12 RLN21647.1 - 0.00078 19.6 0.0 0.02 15.0 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain NaeI PF09126.10 RLN21647.1 - 0.094 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease NaeI FAD_binding_1 PF00667.20 RLN21648.1 - 5.1e-09 36.0 0.0 8.6e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Sharpin_PH PF16764.5 RLN21648.1 - 0.034 13.9 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Sharpin PH domain PPR_long PF17177.4 RLN21649.1 - 0.00067 19.1 0.0 11 5.3 0.0 4.7 3 2 2 6 6 6 3 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 RLN21649.1 - 0.0025 18.0 0.0 7.6 6.8 0.0 5.0 6 0 0 6 6 6 1 PPR repeat family ATP13 PF12921.7 RLN21649.1 - 0.05 13.5 0.0 0.41 10.5 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ATPase expression DcpS_C PF11969.8 RLN21650.1 - 3.5e-18 66.1 0.0 6.9e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 RLN21650.1 - 9.3e-11 42.3 1.8 4.6e-10 40.1 1.8 2.1 1 1 0 1 1 1 1 HIT domain MDFI PF15316.6 RLN21650.1 - 0.89 9.6 8.4 0.094 12.8 2.4 2.2 2 1 0 2 2 2 0 MyoD family inhibitor Apt1 PF10351.9 RLN21650.1 - 4.6 6.0 9.9 0.23 10.2 4.3 1.7 2 0 0 2 2 2 0 Golgi-body localisation protein domain RAP1 PF07218.11 RLN21650.1 - 10 4.3 8.1 21 3.2 8.1 1.6 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.25 RLN21651.1 - 2.7e-50 171.2 0.0 1.3e-41 142.7 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN21651.1 - 4.5e-37 127.7 0.0 4.5e-32 111.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Hat1_N PF10394.9 RLN21651.1 - 3.1e-30 105.5 0.0 5.8e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Pkinase_fungal PF17667.1 RLN21651.1 - 0.00033 19.5 0.0 0.00067 18.5 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN21651.1 - 0.017 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Dynamin_M PF01031.20 RLN21652.1 - 3.4e-110 367.7 0.0 1e-109 366.2 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 RLN21652.1 - 2.2e-57 193.8 0.0 3.8e-57 193.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 RLN21652.1 - 3.1e-27 94.5 1.2 7.9e-27 93.2 1.2 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 RLN21652.1 - 0.00016 21.7 0.3 0.00067 19.7 0.3 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RLN21652.1 - 0.12 12.7 0.0 0.75 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain His_Phos_2 PF00328.22 RLN21653.1 - 9.1e-10 38.4 0.0 0.00043 19.7 0.0 3.1 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Kinesin PF00225.23 RLN21654.1 - 2.4e-95 319.3 0.2 2.4e-95 319.3 0.2 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RLN21654.1 - 3e-30 105.1 4.8 1.1e-27 96.8 0.0 4.5 4 0 0 4 4 4 2 Microtubule binding Atg14 PF10186.9 RLN21654.1 - 0.00044 19.4 14.8 0.00044 19.4 14.8 5.6 2 2 2 4 4 4 2 Vacuolar sorting 38 and autophagy-related subunit 14 Tup_N PF08581.10 RLN21654.1 - 0.0019 18.5 7.4 0.0019 18.5 7.4 8.5 5 3 2 8 8 8 3 Tup N-terminal Fez1 PF06818.15 RLN21654.1 - 0.0021 18.5 19.5 0.0021 18.5 19.5 5.4 2 1 3 5 5 5 2 Fez1 Filament PF00038.21 RLN21654.1 - 0.0029 17.3 40.4 0.0029 17.3 40.4 5.1 2 2 2 5 5 5 2 Intermediate filament protein BT1 PF03092.16 RLN25745.1 - 1.6e-21 76.2 10.8 9.8e-14 50.5 0.6 3.2 3 0 0 3 3 3 3 BT1 family SieB PF14163.6 RLN25745.1 - 4.3 6.8 8.1 7.3 6.1 0.4 2.9 3 0 0 3 3 3 0 Super-infection exclusion protein B Arv1 PF04161.13 RLN25745.1 - 9.1 6.4 7.1 59 3.7 6.2 2.5 2 1 0 2 2 2 0 Arv1-like family ADH_zinc_N PF00107.26 RLN25746.1 - 4.3e-24 85.0 0.2 7.4e-24 84.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN25746.1 - 1.3e-15 58.7 0.0 2.8e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN25746.1 - 8.6e-10 38.5 0.2 2.1e-09 37.3 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 RLN25746.1 - 0.0035 17.2 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 RLN25747.1 - 3.6e-26 91.7 0.1 9.4e-26 90.3 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN25747.1 - 2.6e-16 60.9 0.0 9.3e-16 59.1 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN25747.1 - 2.9e-09 36.8 0.7 1.2e-08 34.8 0.3 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain E1-N PF14463.6 RLN25747.1 - 0.046 13.5 1.1 0.15 11.9 0.3 2.0 1 1 1 2 2 2 0 E1 N-terminal domain Palm_thioest PF02089.15 RLN25747.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Glyco_hydro_72 PF03198.14 RLN25748.1 - 5.3e-19 68.6 0.0 6.2e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Complex1_LYR PF05347.15 RLN25749.1 - 2.6e-13 49.8 1.1 2.6e-13 49.8 1.1 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 RLN25749.1 - 2.1e-05 25.0 0.5 2.4e-05 24.8 0.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 RLN25749.1 - 0.00042 21.0 0.3 0.00049 20.8 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Macro PF01661.21 RLN25750.1 - 8.5e-32 109.7 0.0 1.5e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 Macro domain Laminin_G_3 PF13385.6 RLN25750.1 - 1.1e-08 35.4 3.5 4e-08 33.5 3.5 1.8 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily F-box-like PF12937.7 RLN25750.1 - 6.9e-06 25.9 0.0 1.9e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RLN25750.1 - 0.0013 18.6 0.0 0.0036 17.2 0.0 1.8 1 0 0 1 1 1 1 F-box domain FANC_SAP PF18081.1 RLN25750.1 - 0.053 13.7 0.3 0.29 11.3 0.0 2.3 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain ChitinaseA_N PF08329.10 RLN25750.1 - 0.095 12.3 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 Chitinase A, N-terminal domain MamL-1 PF09596.10 RLN25750.1 - 0.3 11.4 1.1 0.94 9.8 1.1 1.8 1 0 0 1 1 1 0 MamL-1 domain HEAT_2 PF13646.6 RLN25751.1 - 0.0042 17.4 0.0 0.13 12.6 0.0 3.2 3 0 0 3 3 3 1 HEAT repeats Cnd3 PF12719.7 RLN25751.1 - 0.01 15.0 0.0 1.8 7.7 0.0 2.7 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Peptidase_M1 PF01433.20 RLN25751.1 - 0.072 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M1 domain zf-UBR PF02207.20 RLN25752.1 - 1.3e-19 70.1 9.6 1.3e-19 70.1 9.6 2.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 RLN25752.1 - 0.056 13.2 1.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS DNA_ligase_A_N PF04675.14 RLN25752.1 - 0.13 12.5 2.1 1.3 9.3 0.3 2.6 2 0 0 2 2 2 0 DNA ligase N terminus Pkinase_Tyr PF07714.17 RLN25753.1 - 1.3e-26 93.5 0.0 2e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN25753.1 - 7.1e-18 64.9 0.0 1.1e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PDZ_6 PF17820.1 RLN25753.1 - 3.6e-06 26.7 0.1 9.6e-06 25.4 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RLN25753.1 - 1.3e-05 25.4 0.1 2.6e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Laminin_G_3 PF13385.6 RLN25753.1 - 0.015 15.5 0.0 0.097 12.8 0.0 2.3 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Kdo PF06293.14 RLN25753.1 - 0.071 12.5 0.0 0.19 11.0 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PDZ_2 PF13180.6 RLN25753.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Peptidase_M17 PF00883.21 RLN25754.1 - 1.9e-50 172.0 1.9 3.2e-50 171.2 1.9 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 RLN25754.1 - 8.6e-16 58.3 2.0 1.1e-14 54.7 1.6 2.6 2 1 0 2 2 2 1 M17 aminopeptidase N-terminal domain 2 Ribosomal_L19e PF01280.20 RLN25755.1 - 0.035 14.2 0.2 0.079 13.0 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein L19e dsRBD2 PF17842.1 RLN25755.1 - 0.1 12.8 1.3 8.1 6.6 0.0 2.9 2 1 0 2 2 2 0 Double-stranded RNA binding domain 2 Med9 PF07544.13 RLN25755.1 - 0.27 11.4 2.1 19 5.4 0.3 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 BAG PF02179.16 RLN25756.1 - 1.8e-08 34.6 0.7 5.5e-08 33.1 0.7 1.9 1 1 0 1 1 1 1 BAG domain Nop14 PF04147.12 RLN25756.1 - 0.051 11.8 20.0 0.069 11.4 20.0 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 RLN25756.1 - 0.07 11.6 19.6 0.09 11.2 19.6 1.1 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 RLN25756.1 - 0.55 8.5 16.7 0.73 8.1 16.7 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 RLN25756.1 - 1.5 8.3 17.8 2.1 7.8 17.8 1.3 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 RLN25756.1 - 2.8 7.2 22.0 4 6.7 22.0 1.2 1 0 0 1 1 1 0 BUD22 CCSAP PF15748.5 RLN25756.1 - 3.9 7.6 10.5 6.3 6.9 10.5 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Na_trans_assoc PF06512.13 RLN25756.1 - 9.2 6.5 17.6 17 5.6 17.6 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated Spore_coat_CotO PF14153.6 RLN25756.1 - 10 6.0 15.3 20 5.0 15.3 1.4 1 0 0 1 1 1 0 Spore coat protein CotO AAA_33 PF13671.6 RLN25757.1 - 3e-06 27.4 0.0 8.6e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain tRNA_lig_CPD PF08302.11 RLN25757.1 - 4.4e-05 23.1 0.0 7.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_16 PF13191.6 RLN25757.1 - 0.0042 17.5 0.1 0.034 14.5 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 RLN25757.1 - 0.0087 15.4 0.0 0.047 13.0 0.0 2.1 1 1 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 RLN25757.1 - 0.035 14.7 0.0 0.083 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 RLN25757.1 - 0.058 12.8 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CPT PF07931.12 RLN25757.1 - 0.086 12.7 0.0 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF2293 PF10056.9 RLN25758.1 - 0.19 12.0 1.4 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2293) Mak16 PF04874.14 RLN25777.1 - 8.3e-20 71.3 16.0 8.3e-20 71.3 16.0 2.7 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 RLN25777.1 - 0.0043 16.5 25.7 0.005 16.3 25.7 1.0 1 0 0 1 1 1 1 BUD22 CDC45 PF02724.14 RLN25777.1 - 0.054 11.8 21.9 0.063 11.6 21.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Drc1-Sld2 PF11719.8 RLN25777.1 - 0.094 12.2 12.9 0.14 11.7 12.9 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Nop14 PF04147.12 RLN25777.1 - 0.15 10.3 28.2 0.17 10.1 28.2 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RLN25777.1 - 0.15 11.5 28.6 0.16 11.3 28.6 1.1 1 0 0 1 1 1 0 SDA1 SURF2 PF05477.11 RLN25777.1 - 4.1 7.0 15.6 5.4 6.6 15.6 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Apt1 PF10351.9 RLN25777.1 - 6.1 5.6 10.6 8.2 5.2 10.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Mpp10 PF04006.12 RLN25777.1 - 9.1 4.6 32.2 10 4.4 32.2 1.0 1 0 0 1 1 1 0 Mpp10 protein Kinesin PF00225.23 RLN25778.1 - 8.8e-105 350.3 0.0 8.8e-105 350.3 0.0 3.6 4 0 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 RLN25778.1 - 9.1e-19 67.9 2.1 3.3e-18 66.0 0.0 3.2 3 0 0 3 3 3 1 Microtubule binding bZIP_1 PF00170.21 RLN25779.1 - 8.7e-11 41.8 12.5 2e-10 40.6 12.5 1.7 1 0 0 1 1 1 1 bZIP transcription factor Pro_isomerase PF00160.21 RLN25779.1 - 7.1e-08 32.9 0.0 1.4e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD bZIP_2 PF07716.15 RLN25779.1 - 0.00012 22.0 8.3 0.00012 22.0 8.3 1.8 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 RLN25779.1 - 0.00016 22.1 6.1 0.00031 21.2 6.1 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF1889 PF08986.10 RLN25779.1 - 0.019 15.4 0.1 0.065 13.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1889) YabA PF06156.13 RLN25779.1 - 0.11 13.2 0.2 0.21 12.2 0.2 1.4 1 0 0 1 1 1 0 Initiation control protein YabA DUF4407 PF14362.6 RLN25779.1 - 0.19 11.0 1.2 0.33 10.3 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 RLN25779.1 - 0.29 11.2 7.9 0.5 10.4 7.9 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ZapB PF06005.12 RLN25779.1 - 1.2 9.6 6.4 0.24 11.9 2.4 1.8 1 1 1 2 2 2 0 Cell division protein ZapB Methyltransf_11 PF08241.12 RLN25781.1 - 7.7e-10 39.3 0.0 1.3e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN25781.1 - 5.1e-07 29.7 0.0 6.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN25781.1 - 1.6e-06 28.8 0.0 3.3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN25781.1 - 2.3e-06 28.2 0.0 4.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN25781.1 - 0.00055 19.8 0.0 0.0008 19.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN25781.1 - 0.018 14.4 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_7 PF03492.15 RLN25781.1 - 0.053 12.7 0.0 0.074 12.3 0.0 1.1 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Cation_efflux PF01545.21 RLN25782.1 - 2.5e-27 95.9 3.2 3.6e-27 95.4 3.2 1.2 1 0 0 1 1 1 1 Cation efflux family uDENN PF03456.18 RLN25783.1 - 2.1e-13 50.8 0.2 4.5e-13 49.8 0.2 1.5 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 RLN25783.1 - 2.4e-08 33.8 0.3 5.6e-08 32.7 0.3 1.7 1 0 0 1 1 1 1 dDENN domain TraF_2 PF13729.6 RLN25784.1 - 0.0016 17.9 0.6 0.0016 17.9 0.6 2.4 2 1 0 2 2 2 1 F plasmid transfer operon, TraF, protein PI_PP_I PF18363.1 RLN25784.1 - 0.13 12.4 9.2 0.5 10.6 0.2 2.9 2 1 0 2 2 2 0 Phosphoinositide phosphatase insertion domain DUF3584 PF12128.8 RLN25784.1 - 0.93 6.9 66.3 0.0075 13.9 58.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Cytokin_check_N PF10407.9 RLN25784.1 - 1.6 8.7 6.9 0.14 12.2 0.5 2.5 3 0 0 3 3 3 0 Cdc14 phosphatase binding protein N-terminus HOOK PF05622.12 RLN25784.1 - 5.6 5.0 61.8 0.79 7.8 30.3 2.7 1 1 1 2 2 2 0 HOOK protein vATP-synt_AC39 PF01992.16 RLN25785.1 - 3.2e-79 266.9 0.0 7.3e-52 176.9 0.0 2.2 1 1 1 2 2 2 2 ATP synthase (C/AC39) subunit Ank_2 PF12796.7 RLN25815.1 - 1.6e-38 131.1 0.0 1.1e-14 54.8 0.0 5.6 3 1 4 7 7 7 4 Ankyrin repeats (3 copies) TIR_2 PF13676.6 RLN25815.1 - 2.8e-33 115.0 0.0 7e-18 65.4 0.0 2.7 2 0 0 2 2 2 2 TIR domain Ank_4 PF13637.6 RLN25815.1 - 4.6e-31 106.8 0.6 3.2e-09 37.1 0.0 7.4 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN25815.1 - 7.5e-27 90.4 0.7 3e-05 24.1 0.0 8.6 8 1 1 9 9 9 4 Ankyrin repeat Ank PF00023.30 RLN25815.1 - 2.8e-26 90.8 4.1 2.5e-05 24.5 0.0 8.0 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 RLN25815.1 - 9.3e-19 67.3 6.0 2.2e-06 27.8 0.1 7.5 4 1 4 8 8 8 5 Ankyrin repeats (many copies) TIR PF01582.20 RLN25815.1 - 4.6e-11 42.8 0.0 3.5e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 TIR domain DUF1863 PF08937.11 RLN25815.1 - 4.1e-07 30.4 0.0 0.012 15.9 0.1 3.0 2 1 0 2 2 2 2 MTH538 TIR-like domain (DUF1863) Peptidase_C2 PF00648.21 RLN25816.1 - 5.4e-54 183.2 0.2 9.3e-51 172.6 0.0 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.22 RLN25816.1 - 1.4e-05 25.4 0.0 2.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.32 RLN25817.1 - 1.6e-17 61.6 3.9 1.5e-05 24.2 0.1 3.8 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 RLN25817.1 - 1.5e-16 60.6 2.9 6e-10 39.4 0.3 3.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN25817.1 - 3.4e-15 54.6 5.8 2.9e-05 23.7 0.1 4.1 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 RLN25817.1 - 2.9e-14 51.8 8.7 0.00023 20.5 0.1 3.9 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 RLN25817.1 - 1.7e-11 43.8 2.9 0.0038 17.1 0.0 3.8 2 1 1 3 3 3 3 EF-hand domain pair AAA_16 PF13191.6 RLN25817.1 - 0.012 15.9 0.4 0.012 15.9 0.4 4.4 5 1 0 5 5 5 0 AAA ATPase domain V-SNARE PF05008.15 RLN25817.1 - 0.52 10.7 7.1 1.7 9.1 7.1 1.9 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus DZR PF12773.7 RLN25817.1 - 4.8 7.3 7.1 9.8 6.3 7.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon Gp_dh_N PF00044.24 RLN25824.1 - 1.8e-23 82.7 0.0 2e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 RLN25824.1 - 0.026 14.7 0.0 0.026 14.7 0.0 1.1 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 RLN25824.1 - 0.053 12.9 0.0 0.053 12.9 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Macro PF01661.21 RLN25849.1 - 1.2e-24 86.6 0.2 2.3e-24 85.7 0.2 1.5 1 0 0 1 1 1 1 Macro domain CRAL_TRIO_2 PF13716.6 RLN25849.1 - 5e-06 26.7 0.1 9.2e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Caldesmon PF02029.15 RLN25849.1 - 0.7 8.6 4.4 0.96 8.1 4.4 1.1 1 0 0 1 1 1 0 Caldesmon Syja_N PF02383.18 RLN25850.1 - 1.1e-52 179.4 0.0 1.4e-52 179.0 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Flavi_NS2B PF01002.19 RLN25851.1 - 0.0015 18.4 0.1 0.0023 17.8 0.1 1.3 1 0 0 1 1 1 1 Flavivirus non-structural protein NS2B WD40 PF00400.32 RLN25852.1 - 5.2e-05 23.9 3.1 0.88 10.5 0.2 5.9 5 1 1 6 6 6 1 WD domain, G-beta repeat Abhydrolase_3 PF07859.13 RLN25852.1 - 0.12 12.2 1.7 0.89 9.4 0.3 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold WD40 PF00400.32 RLN25860.1 - 2.3e-09 37.7 0.5 0.043 14.7 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN25860.1 - 0.00012 22.3 0.0 0.042 14.2 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain SCAB-ABD PF16711.5 RLN25860.1 - 0.076 12.9 1.2 12 5.8 0.0 2.7 2 0 0 2 2 2 0 Actin-binding domain of plant-specific actin-binding protein DUF3818 PF12825.7 RLN25860.1 - 0.14 11.2 0.4 0.22 10.5 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) PEP-utilisers_N PF05524.13 RLN25860.1 - 0.18 12.0 3.7 0.4 10.9 2.8 1.9 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal HAUS-augmin3 PF14932.6 RLN25860.1 - 0.35 10.4 6.8 0.56 9.7 6.8 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 TSC22 PF01166.18 RLN25860.1 - 3.1 8.2 6.0 26 5.2 0.5 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family JIP_LZII PF16471.5 RLN25860.1 - 6 7.1 10.6 1.7 8.9 2.6 2.5 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II LRR_6 PF13516.6 RLN25861.1 - 3.5e-07 29.7 6.9 0.11 12.6 0.1 5.4 5 0 0 5 5 5 2 Leucine Rich repeat LRR_8 PF13855.6 RLN25861.1 - 4.7e-06 26.3 2.1 0.057 13.2 0.0 3.9 3 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 RLN25861.1 - 7e-06 25.9 0.3 0.16 12.7 0.1 5.1 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_4 PF12799.7 RLN25861.1 - 0.00016 22.0 6.0 0.16 12.4 0.5 4.6 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) DUF3073 PF11273.8 RLN25861.1 - 0.067 13.9 1.3 0.63 10.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3073) Rad4 PF03835.15 RLN25862.1 - 0.15 11.7 1.1 8.5 6.0 0.1 2.6 2 0 0 2 2 2 0 Rad4 transglutaminase-like domain YHYH PF14240.6 RLN25864.1 - 2.1e-24 86.6 1.8 3.2e-12 46.8 0.0 4.8 2 2 2 4 4 4 4 YHYH protein Pkinase PF00069.25 RLN25866.1 - 1.3e-47 162.4 0.0 2.2e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN25866.1 - 5.4e-46 157.0 0.0 8.4e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RLN25866.1 - 0.022 13.7 0.1 0.068 12.1 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Sporozoite_P67 PF05642.11 RLN25866.1 - 0.34 8.9 4.6 0.43 8.6 4.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PIN_8 PF18476.1 RLN25867.1 - 0.83 9.5 4.7 0.6 9.9 1.6 1.9 1 1 1 2 2 2 0 PIN like domain DARPP-32 PF05395.12 RLN25867.1 - 0.87 9.8 3.9 2 8.6 3.7 1.7 1 1 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Trehalase PF01204.18 RLN25868.1 - 1.8e-136 456.0 0.0 2e-136 455.8 0.0 1.0 1 0 0 1 1 1 1 Trehalase Glyco_hydro_63 PF03200.16 RLN25868.1 - 0.015 14.1 0.2 0.9 8.2 0.1 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 63 C-terminal domain DUF4148 PF13663.6 RLN25868.1 - 0.35 11.1 2.0 0.46 10.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) UFC1 PF08694.11 RLN25870.1 - 6.4e-47 159.0 0.3 1.1e-45 155.1 0.3 2.0 1 1 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 Helicase_C_2 PF13307.6 RLN25872.1 - 2.7e-13 50.5 0.0 8.5e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 RLN25872.1 - 9.3e-12 44.9 0.3 1.7e-11 44.1 0.3 1.4 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 RLN25872.1 - 0.00013 21.8 0.1 0.00028 20.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 RLN25872.1 - 0.00096 19.2 0.0 0.0034 17.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit YadA_stalk PF05662.14 RLN25872.1 - 0.21 12.0 2.8 9.8 6.6 0.5 2.7 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin Methyltransf_10 PF05971.12 RLN25873.1 - 4.3e-61 206.9 1.5 4.8e-59 200.1 1.5 2.7 1 1 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 RLN25873.1 - 3e-09 36.6 0.0 4.6e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 RLN25873.1 - 0.00033 20.1 0.0 0.00048 19.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 RLN25873.1 - 0.0021 17.8 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 RLN25873.1 - 0.071 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase TrmK PF04816.12 RLN25873.1 - 0.079 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_25 PF13649.6 RLN25873.1 - 0.093 13.4 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 RLN25873.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 RLN25873.1 - 0.2 11.4 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein TPR_1 PF00515.28 RLN25874.1 - 4.2e-11 42.2 11.4 5.1e-05 22.9 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN25874.1 - 6.2e-11 41.5 18.2 1.9e-05 24.4 0.0 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN25874.1 - 7.3e-08 32.9 15.0 0.00018 22.1 0.1 4.4 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN25874.1 - 1.8e-07 30.7 4.2 0.01 15.8 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN25874.1 - 3.1e-07 30.1 13.3 0.0094 16.1 0.0 6.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN25874.1 - 5.5e-07 29.2 5.8 4.6e-06 26.2 0.0 4.4 4 1 1 5 5 5 2 TPR repeat TPR_17 PF13431.6 RLN25874.1 - 2.3e-06 27.6 0.1 1.8e-05 24.8 0.0 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN25874.1 - 3.9e-06 27.1 4.7 0.00041 20.6 0.3 4.8 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 RLN25874.1 - 4.5e-05 23.2 12.2 0.017 15.0 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN25874.1 - 0.00015 22.3 8.6 0.34 11.9 0.1 4.9 3 1 3 6 6 6 2 Tetratricopeptide repeat Complex1_LYR PF05347.15 RLN25874.1 - 0.00058 19.9 0.3 0.69 10.0 0.1 2.7 2 0 0 2 2 2 2 Complex 1 protein (LYR family) TPR_19 PF14559.6 RLN25874.1 - 0.0017 18.8 0.1 0.0017 18.8 0.1 3.3 3 2 0 3 3 3 1 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 RLN25874.1 - 0.0077 15.7 1.9 0.019 14.4 0.0 2.2 2 1 1 3 3 3 1 Est1 DNA/RNA binding domain TPR_6 PF13174.6 RLN25874.1 - 0.0078 16.8 2.6 2 9.2 0.0 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat BTAD PF03704.17 RLN25874.1 - 0.026 15.0 4.9 0.078 13.4 4.3 2.2 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_4 PF07721.14 RLN25874.1 - 0.04 14.6 0.9 12 6.9 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HBM PF16591.5 RLN25874.1 - 0.13 11.6 6.7 4.6 6.6 0.0 2.5 2 1 0 2 2 2 0 Helical bimodular sensor domain Pkinase PF00069.25 RLN25875.1 - 1.5e-17 63.9 0.0 3.5e-16 59.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN25875.1 - 8.6e-14 51.4 0.0 5.2e-13 48.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase AAA PF00004.29 RLN25876.1 - 1.1e-61 207.1 0.1 4e-30 104.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN25876.1 - 3.3e-12 47.1 1.7 2.3e-06 28.1 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_lid_3 PF17862.1 RLN25876.1 - 5e-11 42.2 0.7 0.00046 19.9 0.4 2.5 2 0 0 2 2 2 2 AAA+ lid domain IstB_IS21 PF01695.17 RLN25876.1 - 2.9e-09 36.9 0.1 9.2e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.13 RLN25876.1 - 5e-09 35.8 0.1 0.0029 16.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 RLN25876.1 - 1.4e-08 35.0 0.0 0.004 17.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 RLN25876.1 - 6.5e-08 33.2 0.0 0.012 16.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 RLN25876.1 - 4.4e-07 30.0 1.9 0.019 14.9 0.0 3.8 2 2 1 3 3 3 2 NACHT domain RuvB_N PF05496.12 RLN25876.1 - 4.8e-07 29.7 0.7 0.03 14.1 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RLN25876.1 - 8.4e-07 29.1 0.0 0.0059 16.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RLN25876.1 - 2.7e-06 27.6 0.0 0.0022 18.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 RLN25876.1 - 2.8e-06 27.4 0.0 0.013 15.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RLN25876.1 - 5.7e-06 26.6 0.6 0.12 12.6 0.0 3.6 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 RLN25876.1 - 6.2e-06 26.0 0.0 0.0018 18.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NTPase_1 PF03266.15 RLN25876.1 - 1.1e-05 25.4 0.4 0.011 15.6 0.0 2.5 2 0 0 2 2 2 1 NTPase AAA_17 PF13207.6 RLN25876.1 - 1.1e-05 25.9 0.0 0.25 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 RLN25876.1 - 3.1e-05 24.3 0.3 0.023 15.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 RLN25876.1 - 3.5e-05 23.2 0.2 0.0046 16.3 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.27 RLN25876.1 - 3.5e-05 24.3 0.0 0.93 10.0 0.1 3.5 2 2 0 2 2 2 2 ABC transporter Mg_chelatase PF01078.21 RLN25876.1 - 4.8e-05 22.8 0.0 0.033 13.6 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 RLN25876.1 - 5.1e-05 23.3 0.0 0.33 11.0 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 RLN25876.1 - 6.9e-05 23.2 0.0 0.61 10.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.6 RLN25876.1 - 0.00026 20.8 0.8 0.068 12.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 RLN25876.1 - 0.00034 20.5 0.0 1.3 8.8 0.0 2.6 3 0 0 3 3 2 2 Bacterial dnaA protein AAA_3 PF07726.11 RLN25876.1 - 0.00035 20.4 0.0 0.64 9.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 RLN25876.1 - 0.0011 18.2 0.1 0.29 10.3 0.0 2.6 3 0 0 3 3 2 1 NB-ARC domain AAA_24 PF13479.6 RLN25876.1 - 0.0015 18.3 0.1 1 9.0 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_28 PF13521.6 RLN25876.1 - 0.0017 18.6 0.0 0.54 10.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain Parvo_NS1 PF01057.17 RLN25876.1 - 0.0033 16.5 0.0 0.11 11.5 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_29 PF13555.6 RLN25876.1 - 0.0049 16.6 0.3 0.16 11.7 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 RLN25876.1 - 0.0051 16.6 0.3 0.99 9.1 0.0 3.0 4 0 0 4 4 3 1 Viral (Superfamily 1) RNA helicase cobW PF02492.19 RLN25876.1 - 0.0068 16.0 0.9 1.5 8.4 0.0 3.2 3 1 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain KTI12 PF08433.10 RLN25876.1 - 0.0071 15.8 0.1 0.62 9.5 0.0 2.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 T2SSE PF00437.20 RLN25876.1 - 0.011 14.8 0.1 0.31 10.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_7 PF12775.7 RLN25876.1 - 0.012 15.1 0.0 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 RLN25876.1 - 0.018 14.7 0.7 1.8 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 RLN25876.1 - 0.018 14.2 0.0 0.81 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) APS_kinase PF01583.20 RLN25876.1 - 0.022 14.6 0.1 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase Sigma54_activ_2 PF14532.6 RLN25876.1 - 0.024 14.8 0.0 1.5 8.9 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_11 PF13086.6 RLN25876.1 - 0.025 14.4 0.0 0.28 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 RLN25876.1 - 0.025 13.8 0.3 3.9 6.6 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) GvpD PF07088.11 RLN25876.1 - 0.046 12.3 0.1 0.48 9.0 0.0 2.3 2 0 0 2 2 2 0 GvpD gas vesicle protein SMC_N PF02463.19 RLN25876.1 - 0.047 13.1 0.0 1.9 7.8 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RHH_6 PF16762.5 RLN25876.1 - 0.05 14.2 0.0 4 8.1 0.0 2.6 2 0 0 2 2 2 0 Ribbon-helix-helix domain Hpr_kinase_C PF07475.12 RLN25876.1 - 0.056 13.0 0.1 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain DnaB_C PF03796.15 RLN25876.1 - 0.064 12.6 0.1 10 5.4 0.0 2.5 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain DUF4125 PF13526.6 RLN25878.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4125) WW PF00397.26 RLN25879.1 - 1.4e-20 73.1 20.3 7.1e-07 29.2 2.8 3.6 3 0 0 3 3 3 3 WW domain IQ PF00612.27 RLN25879.1 - 1.5e-07 30.6 6.5 0.022 14.5 0.1 3.9 3 0 0 3 3 3 2 IQ calmodulin-binding motif AIF_C PF14721.6 RLN25879.1 - 0.0045 17.3 4.5 0.4 11.0 0.3 2.7 2 0 0 2 2 2 2 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3974 PF13120.6 RLN25879.1 - 0.18 11.9 1.1 0.75 9.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) Eapp_C PF10238.9 RLN25879.1 - 0.28 11.2 2.4 5.5 7.1 0.1 2.5 2 0 0 2 2 2 0 E2F-associated phosphoprotein FAM176 PF14851.6 RLN25879.1 - 0.55 9.9 7.9 1.8 8.2 0.7 2.7 2 0 0 2 2 2 0 FAM176 family YL1_C PF08265.11 RLN25879.1 - 6.7 6.6 5.8 4.2 7.2 1.3 2.3 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain Ribosomal_L27A PF00828.19 RLN25880.1 - 3.4e-24 86.0 0.1 5e-24 85.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L18 PF17135.4 RLN25880.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e DUF4988 PF16378.5 RLN25880.1 - 0.099 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function Vps53_N PF04100.12 RLN25905.1 - 2.7e-102 342.6 4.6 5.5e-102 341.6 4.6 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal Sec6 PF06046.13 RLN25905.1 - 4.9e-11 41.7 0.5 9.7e-07 27.5 0.1 2.9 3 0 0 3 3 3 2 Exocyst complex component Sec6 Vps54_N PF10475.9 RLN25905.1 - 4.7e-09 36.0 3.5 1.2e-08 34.6 3.5 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG7 PF10191.9 RLN25905.1 - 4.3e-06 25.3 4.4 0.00033 19.0 0.1 2.5 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) COG5 PF10392.9 RLN25905.1 - 0.00032 20.9 2.6 0.00082 19.6 2.6 1.8 1 0 0 1 1 1 1 Golgi transport complex subunit 5 RINT1_TIP1 PF04437.13 RLN25905.1 - 0.005 15.8 0.1 0.028 13.3 0.1 2.2 1 1 0 1 1 1 1 RINT-1 / TIP-1 family VPS53_C PF16854.5 RLN25905.1 - 0.0065 16.4 1.6 0.0093 15.9 0.0 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 53 C-terminus SIP1 PF04938.12 RLN25905.1 - 0.018 14.8 2.6 0.094 12.4 1.0 2.9 2 1 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) FUSC PF04632.12 RLN25905.1 - 0.78 8.2 3.8 1.2 7.5 3.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 RLN25905.1 - 6.4 6.8 6.0 6.3 6.9 1.7 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) ACT_7 PF13840.6 RLN25914.1 - 5.2e-29 99.8 0.2 5.4e-17 61.3 0.0 3.3 3 0 0 3 3 3 3 ACT domain Castor1_N PF18700.1 RLN25914.1 - 0.00011 22.0 0.3 0.043 13.7 0.0 2.6 2 0 0 2 2 2 2 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain DUF4908 PF16252.5 RLN25914.1 - 0.072 12.6 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4908) Ank_2 PF12796.7 RLN25915.1 - 1.1e-27 96.5 20.1 7.3e-09 36.1 0.4 4.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN25915.1 - 2e-24 85.6 11.1 3.7e-06 27.4 0.6 7.7 7 2 1 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN25915.1 - 1.4e-18 66.7 15.4 0.013 15.8 0.0 10.0 4 3 7 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN25915.1 - 2.2e-14 52.1 6.8 5.2 8.0 0.1 10.0 9 2 2 11 11 11 3 Ankyrin repeat DUF5049 PF16468.5 RLN25915.1 - 0.0019 18.0 0.1 48 3.9 0.0 5.1 4 1 2 6 6 6 0 Domain of unknown function (DUF5049) Ank PF00023.30 RLN25915.1 - 0.071 13.6 1.7 35 5.1 0.1 5.4 5 1 1 6 6 6 0 Ankyrin repeat DUF1987 PF09345.10 RLN25915.1 - 5.6 6.7 6.2 48 3.7 0.0 4.0 6 0 0 6 6 6 0 Domain of unknown function (DUF1987) DFRP_C PF16543.5 RLN25920.1 - 3.4e-18 65.9 3.9 3.4e-18 65.9 3.9 3.5 2 2 0 2 2 2 1 DRG Family Regulatory Proteins, Tma46 zf_CCCH_4 PF18345.1 RLN25920.1 - 6.1e-06 26.1 4.2 1.2e-05 25.2 4.2 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 RLN25920.1 - 2.1e-05 24.3 1.4 3.4e-05 23.6 1.4 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 RLN25920.1 - 3.4e-05 24.5 0.1 3.4e-05 24.5 0.1 3.1 3 0 0 3 3 3 1 Torus domain zf-CCCH_4 PF18044.1 RLN25920.1 - 0.00031 20.5 1.4 0.00067 19.4 1.4 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 RLN25920.1 - 0.029 14.9 1.7 0.052 14.0 1.7 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Ribosomal_60s PF00428.19 RLN25920.1 - 0.034 14.7 2.1 0.034 14.7 2.1 4.4 3 2 1 4 4 4 0 60s Acidic ribosomal protein zf-CCCH_3 PF15663.5 RLN25920.1 - 0.1 12.8 0.4 0.25 11.6 0.4 1.6 1 0 0 1 1 1 0 Zinc-finger containing family STT3 PF02516.14 RLN25921.1 - 2.9e-92 310.1 28.2 1.8e-91 307.5 28.2 1.8 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Pkinase_Tyr PF07714.17 RLN25923.1 - 1.1e-49 169.0 0.0 1.4e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN25923.1 - 1.3e-49 168.9 0.0 1.8e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 RLN25923.1 - 0.084 12.8 0.0 0.22 11.4 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN25923.1 - 0.11 11.4 0.0 0.22 10.4 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain DNA_ligase_A_M PF01068.21 RLN25924.1 - 9.3e-30 103.8 0.1 2.8e-20 72.8 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 RLN25924.1 - 1.7e-25 89.5 0.1 7.9e-25 87.3 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_A_N PF04675.14 RLN25924.1 - 3.5e-07 30.7 1.0 6.8e-05 23.3 0.1 2.8 2 1 1 3 3 3 2 DNA ligase N terminus RNA_ligase PF09414.10 RLN25924.1 - 0.00046 20.5 0.0 0.00087 19.6 0.0 1.5 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 RLN25924.1 - 0.0053 16.8 2.7 0.28 11.2 0.2 2.7 2 0 0 2 2 2 2 DNA ligase OB-like domain PH PF00169.29 RLN25925.1 - 0.12 12.9 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 PH domain GPI-anchored PF10342.9 RLN25926.1 - 9.8e-05 23.0 0.1 0.00026 21.7 0.0 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ion_trans PF00520.31 RLN25929.1 - 5.5e-20 71.6 11.1 8.1e-20 71.1 11.1 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RLN25929.1 - 5.9e-15 55.0 6.3 5.9e-15 55.0 6.3 3.2 3 1 1 4 4 4 1 Ion channel PKD_channel PF08016.12 RLN25929.1 - 5.8e-06 25.2 1.7 9e-06 24.6 1.7 1.2 1 0 0 1 1 1 1 Polycystin cation channel DZR PF12773.7 RLN25929.1 - 0.0004 20.4 0.3 0.00066 19.7 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 RLN25929.1 - 0.0058 16.3 1.1 0.011 15.4 1.1 1.5 1 0 0 1 1 1 1 zinc-ribbon domain NOB1_Zn_bind PF08772.11 RLN25929.1 - 0.062 13.5 0.3 0.11 12.7 0.3 1.4 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.6 RLN25929.1 - 0.063 12.7 0.2 0.14 11.6 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Lig_chan PF00060.26 RLN25929.1 - 0.067 13.0 0.6 11 5.9 0.1 2.5 2 0 0 2 2 2 0 Ligand-gated ion channel Prok-RING_1 PF14446.6 RLN25929.1 - 0.16 11.9 0.5 0.28 11.1 0.5 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF2434 PF10361.9 RLN25929.1 - 0.28 10.1 6.0 1.3 8.0 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2434) Voltage_CLC PF00654.20 RLN25930.1 - 3.9e-81 273.1 28.7 3.9e-81 273.1 28.7 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel ISN1 PF06437.11 RLN25930.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase TAT_signal PF10518.9 RLN25930.1 - 5 7.1 9.2 0.36 10.7 2.9 2.6 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence KAR9 PF08580.10 RLN25949.1 - 0.98 7.9 4.6 1 7.8 4.6 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SWIB PF02201.18 RLN25950.1 - 1.4e-58 194.7 0.4 2.5e-28 97.7 0.0 2.6 3 0 0 3 3 2 2 SWIB/MDM2 domain DEK_C PF08766.11 RLN25950.1 - 2.4e-16 59.4 0.3 4e-15 55.5 0.6 2.4 2 0 0 2 2 2 1 DEK C terminal domain YL1 PF05764.13 RLN25950.1 - 0.0043 17.2 14.6 0.0043 17.2 14.6 2.4 2 1 0 2 2 2 1 YL1 nuclear protein TIMELESS_C PF05029.13 RLN25950.1 - 0.0048 16.1 12.2 0.0048 16.1 12.2 2.2 2 0 0 2 2 2 2 Timeless protein C terminal region DUF2052 PF09747.9 RLN25950.1 - 0.0073 16.5 18.5 0.013 15.7 14.1 2.4 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) DAP10 PF07213.11 RLN25950.1 - 0.16 11.9 0.0 4.7 7.2 0.0 2.2 2 0 0 2 2 2 0 DAP10 membrane protein RR_TM4-6 PF06459.12 RLN25950.1 - 0.25 11.1 18.1 0.14 12.0 12.4 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 RLN25950.1 - 0.36 8.7 3.3 2.2 6.1 1.6 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF3807 PF12720.7 RLN25950.1 - 0.49 10.6 18.8 0.075 13.3 8.2 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF3807) Sigma70_ner PF04546.13 RLN25950.1 - 0.9 9.4 15.8 0.57 10.0 10.8 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region PTPRCAP PF15713.5 RLN25950.1 - 2.5 8.4 22.5 2.5 8.4 16.1 2.6 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated GAGA_bind PF06217.12 RLN25950.1 - 2.8 8.1 11.4 1.8 8.8 6.0 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family Sporozoite_P67 PF05642.11 RLN25950.1 - 3 5.8 11.8 0.028 12.5 3.9 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF2868 PF11067.8 RLN25950.1 - 4.8 6.6 9.0 0.87 9.0 5.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) Hid1 PF12722.7 RLN25950.1 - 5.6 5.0 8.8 0.41 8.7 4.1 1.5 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Pes-10 PF07149.11 RLN25950.1 - 7 5.6 10.9 13 4.7 10.9 1.3 1 0 0 1 1 1 0 Pes-10 DUF913 PF06025.12 RLN25950.1 - 9.3 5.1 8.3 9.3 5.1 5.4 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) PDZ PF00595.24 RLN25952.1 - 1e-08 35.4 0.0 2.2e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 RLN25952.1 - 0.0069 16.2 0.1 5.5 6.9 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Suf PF05843.14 RLN25952.1 - 0.47 10.4 6.7 8.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 RLN25952.1 - 2.9 7.4 11.3 4.4 6.9 11.3 1.3 1 0 0 1 1 1 0 Spt20 family DNA_photolyase PF00875.18 RLN25953.1 - 1.6e-07 31.5 0.7 7.2e-07 29.3 0.7 2.1 1 1 0 1 1 1 1 DNA photolyase FAD_binding_7 PF03441.14 RLN25953.1 - 8.7e-05 22.1 2.1 0.00014 21.4 1.3 1.7 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase RINGv PF12906.7 RLN25954.1 - 2.3e-14 53.3 6.0 2.3e-14 53.3 6.0 1.9 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.6 RLN25954.1 - 0.0028 18.0 6.0 0.0064 16.8 6.0 1.7 1 0 0 1 1 1 1 Ring finger domain CENP-F_leu_zip PF10473.9 RLN25955.1 - 0.0017 18.4 19.4 0.18 11.8 2.9 3.1 2 1 1 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Titin_Ig-rpts PF06582.12 RLN25955.1 - 0.87 9.6 4.8 50 4.0 0.1 3.6 3 0 0 3 3 3 0 Titin repeat AAA_25 PF13481.6 RLN25963.1 - 0.026 14.1 0.1 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Y_phosphatase PF00102.27 RLN25963.1 - 0.037 13.6 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase AAA_10 PF12846.7 RLN25963.1 - 0.12 11.3 0.1 0.27 10.1 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain Albumin_I_a PF16720.5 RLN25978.1 - 0.00044 20.1 0.1 1.9 8.4 0.0 2.9 2 0 0 2 2 2 2 Albumin I chain a DUF973 PF06157.11 RLN25978.1 - 0.001 18.2 0.0 1.4 7.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF973) Lyase_8_C PF02884.17 RLN25978.1 - 0.084 13.4 0.2 91 3.6 0.0 4.3 4 0 0 4 4 4 0 Polysaccharide lyase family 8, C-terminal beta-sandwich domain zf-C2HC_2 PF13913.6 RLN25978.1 - 0.11 12.4 2.4 12 5.9 0.2 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type TIG PF01833.24 RLN25978.1 - 0.3 11.2 3.5 93 3.2 0.3 4.7 3 1 0 3 3 3 0 IPT/TIG domain Toxin_18 PF08087.11 RLN25978.1 - 0.86 9.6 5.9 43 4.2 0.1 4.7 4 0 0 4 4 4 0 Conotoxin O-superfamily Kazal_2 PF07648.15 RLN25978.1 - 9.7 6.4 27.3 7.9 6.7 0.9 5.6 5 0 0 5 5 5 0 Kazal-type serine protease inhibitor domain DnaJ_C PF01556.18 RLN25979.1 - 3.6e-41 140.7 0.5 5e-41 140.2 0.5 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RLN25979.1 - 7.6e-23 80.4 0.1 1.4e-22 79.5 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 RLN25979.1 - 8.8e-15 54.8 19.3 1.6e-14 54.0 19.3 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 RLN25979.1 - 0.025 14.6 10.5 0.27 11.2 1.1 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 RLN25979.1 - 0.1 12.6 7.0 3.8 7.6 0.3 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 RLN25979.1 - 0.23 11.5 7.5 2.3 8.3 1.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 RLN25979.1 - 7.8 6.6 8.2 43 4.2 7.9 2.1 1 1 1 2 2 2 0 zinc-ribbons zf-RING_10 PF16685.5 RLN25979.1 - 9.4 6.5 7.6 0.65 10.2 1.4 2.0 1 1 1 2 2 2 0 zinc RING finger of MSL2 ABC2_membrane PF01061.24 RLN26005.1 - 3.2e-30 105.1 30.8 6e-30 104.2 30.8 1.4 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN26005.1 - 0.0055 16.6 0.1 0.0055 16.6 0.1 3.1 3 1 1 4 4 4 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 RLN26005.1 - 0.69 9.0 25.5 0.023 13.8 18.6 1.9 1 1 1 2 2 2 0 ABC-2 family transporter protein Lig_chan PF00060.26 RLN26005.1 - 5.4 6.9 9.3 1.1e+02 2.5 9.3 2.4 1 1 0 1 1 1 0 Ligand-gated ion channel Fungal_KA1 PF16797.5 RLN26006.1 - 1.1 8.9 4.4 0.67 9.7 0.5 2.5 3 0 0 3 3 3 0 Fungal kinase associated-1 domain YkyA PF10368.9 RLN26006.1 - 4.3 7.0 6.2 17 5.1 0.5 2.7 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein Ras PF00071.22 RLN26007.1 - 5.4e-54 182.2 0.0 7.4e-54 181.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN26007.1 - 5.6e-29 100.8 0.0 8.9e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN26007.1 - 4.9e-14 52.2 0.1 6.3e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RLN26007.1 - 1.5e-06 28.2 0.0 0.0014 18.6 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RLN26007.1 - 1.5e-05 25.0 0.0 2.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RLN26007.1 - 9.7e-05 22.0 0.1 0.00033 20.3 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 RLN26007.1 - 0.00099 18.5 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 RLN26007.1 - 0.0011 18.4 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 RLN26007.1 - 0.0019 18.6 0.1 0.0049 17.3 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 RLN26007.1 - 0.0042 17.4 0.3 0.02 15.2 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 RLN26007.1 - 0.0083 16.3 0.0 0.025 14.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 RLN26007.1 - 0.023 14.2 0.0 0.51 9.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 RLN26007.1 - 0.042 14.1 0.1 0.63 10.3 0.1 2.6 1 1 1 2 2 2 0 AAA domain PduV-EutP PF10662.9 RLN26007.1 - 0.052 13.3 0.0 0.28 10.9 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation BDV_P40 PF06407.11 RLN26007.1 - 0.052 12.6 0.0 0.15 11.2 0.0 1.5 1 1 0 1 1 1 0 Borna disease virus P40 protein FeoB_N PF02421.18 RLN26007.1 - 0.056 13.0 0.1 0.24 10.9 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_5 PF07728.14 RLN26007.1 - 0.057 13.4 0.0 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DLIC PF05783.11 RLN26007.1 - 0.13 11.1 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_24 PF13479.6 RLN26007.1 - 0.13 11.9 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain 60KD_IMP PF02096.20 RLN26009.1 - 6.6e-07 29.4 1.1 9.4e-07 28.9 1.1 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF676 PF05057.14 RLN26010.1 - 1.4e-26 93.4 0.0 2.3e-23 82.9 0.0 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Palm_thioest PF02089.15 RLN26010.1 - 0.00014 21.8 0.0 0.00027 20.9 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 RLN26010.1 - 0.0057 17.3 0.1 0.016 15.8 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.16 RLN26010.1 - 0.03 13.9 0.0 0.099 12.2 0.0 1.8 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Abhydrolase_5 PF12695.7 RLN26010.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family FYVE PF01363.21 RLN26012.1 - 4.3e-17 62.0 6.5 7.7e-17 61.2 6.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN26012.1 - 0.016 15.4 5.7 0.016 15.4 5.7 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger PH PF00169.29 RLN26012.1 - 0.02 15.4 0.0 0.045 14.3 0.0 1.6 1 0 0 1 1 1 0 PH domain MtaB PF12176.8 RLN26012.1 - 0.059 12.2 1.1 0.076 11.8 1.1 1.1 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit MCU PF04678.13 RLN26012.1 - 0.23 11.6 3.1 0.43 10.6 2.7 1.6 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Glyco_hydro_30 PF02055.16 RLN26013.1 - 1e-105 353.6 5.3 1.3e-105 353.2 4.7 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 RLN26013.1 - 4e-10 39.7 0.0 9.8e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain WW PF00397.26 RLN26015.1 - 2.6e-09 37.0 3.8 5.7e-09 35.9 3.8 1.6 1 0 0 1 1 1 1 WW domain DnaJ_CXXCXGXG PF00684.19 RLN26015.1 - 0.5 10.8 10.1 2.8 8.4 10.1 2.3 1 1 0 1 1 1 0 DnaJ central domain Glycos_transf_2 PF00535.26 RLN26016.1 - 0.014 15.3 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 RLN26016.1 - 0.035 14.0 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 PH PF00169.29 RLN26017.1 - 2.9e-13 50.2 0.0 9.3e-13 48.6 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 RLN26017.1 - 3.4e-07 30.6 0.0 1.9e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain Prok-TraM PF09228.10 RLN26017.1 - 0.0032 17.8 1.8 0.0043 17.4 0.2 2.1 2 0 0 2 2 2 1 Prokaryotic Transcriptional repressor TraM Ada3 PF10198.9 RLN26017.1 - 0.061 13.5 4.3 0.14 12.3 3.3 2.1 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 YabA PF06156.13 RLN26017.1 - 1 10.0 7.7 0.39 11.4 1.3 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Spc7 PF08317.11 RLN26017.1 - 1 8.1 10.0 2.2 7.1 10.0 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Ssu72 PF04722.13 RLN26018.1 - 5.3e-47 159.9 0.0 4.9e-46 156.7 0.0 1.9 1 1 0 1 1 1 1 Ssu72-like protein Glyco_tranf_2_3 PF13641.6 RLN26019.1 - 2.2e-05 24.5 0.0 3.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 SNRNP27 PF08648.12 RLN26019.1 - 0.069 13.2 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins DUSP PF06337.12 RLN26114.1 - 2.1e-13 50.7 0.1 4e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 DUSP domain C2 PF00168.30 RLN26114.1 - 8.4e-08 32.4 0.0 0.00018 21.8 0.0 2.4 2 0 0 2 2 2 2 C2 domain BSD PF03909.17 RLN26115.1 - 8.2e-06 25.7 0.2 8.4e-05 22.5 0.1 2.3 2 0 0 2 2 2 1 BSD domain Podoplanin PF05808.11 RLN26116.1 - 0.00026 21.1 2.5 0.00058 20.0 2.5 1.5 1 0 0 1 1 1 1 Podoplanin EphA2_TM PF14575.6 RLN26116.1 - 0.0007 20.4 0.0 0.0012 19.7 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 RLN26116.1 - 0.012 15.6 0.3 0.034 14.0 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family RCR PF12273.8 RLN26116.1 - 0.034 14.8 0.0 0.071 13.8 0.0 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Protocadherin PF08374.11 RLN26116.1 - 0.079 12.9 0.7 0.13 12.2 0.7 1.3 1 0 0 1 1 1 0 Protocadherin GT87 PF09594.10 RLN26116.1 - 0.08 12.6 1.3 0.14 11.8 1.3 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 87 DUF4448 PF14610.6 RLN26116.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Amnionless PF14828.6 RLN26116.1 - 0.11 11.3 0.3 0.15 10.8 0.3 1.1 1 0 0 1 1 1 0 Amnionless DUF5305 PF17231.2 RLN26116.1 - 0.42 10.0 2.4 0.45 9.9 0.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Beta-APP PF03494.13 RLN26116.1 - 0.45 10.4 5.8 1.2 9.0 5.8 1.7 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) CBM64 PF18666.1 RLN26117.1 - 0.08 13.0 1.1 0.27 11.3 0.5 2.2 2 1 1 3 3 3 0 Carbohydrate-binding module 64 PKD_channel PF08016.12 RLN26119.1 - 8e-24 84.1 15.8 8e-17 61.0 16.1 3.2 3 0 0 3 3 3 3 Polycystin cation channel Ion_trans PF00520.31 RLN26119.1 - 3.9e-05 23.0 20.7 5.3e-05 22.6 18.8 2.2 2 1 0 2 2 2 1 Ion transport protein DUF373 PF04123.13 RLN26119.1 - 0.36 10.2 6.4 0.71 9.3 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DctQ PF04290.12 RLN26119.1 - 1 9.3 18.0 0.099 12.6 9.5 3.1 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component ABC2_membrane_2 PF12679.7 RLN26119.1 - 6.3 6.0 10.8 22 4.2 9.0 2.4 2 0 0 2 2 2 0 ABC-2 family transporter protein Med21 PF11221.8 RLN26120.1 - 0.089 13.0 2.2 0.2 11.9 2.2 1.7 1 1 0 1 1 1 0 Subunit 21 of Mediator complex zf-RING_2 PF13639.6 RLN26121.1 - 0.0018 18.6 10.1 0.0018 18.6 10.1 2.7 2 1 0 2 2 2 1 Ring finger domain Rop-like PF05082.13 RLN26121.1 - 0.056 13.3 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Rop-like zf-C3HC4 PF00097.25 RLN26121.1 - 8.1 6.4 13.6 2.5 8.0 7.7 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Csd3_N PF18059.1 RLN26122.1 - 0.015 15.8 0.4 0.022 15.3 0.4 1.5 1 1 0 1 1 1 0 Csd3 N-terminal DUF2407_C PF13373.6 RLN26123.1 - 2.5e-18 66.6 0.1 4.6e-18 65.7 0.1 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.23 RLN26123.1 - 1.9e-13 50.0 0.0 5e-13 48.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family PTPS PF01242.19 RLN26123.1 - 3e-12 46.6 0.0 5.9e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase DUF2407 PF10302.9 RLN26123.1 - 9.4e-05 22.9 0.0 0.00025 21.6 0.0 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 RLN26123.1 - 0.0017 18.4 0.2 0.12 12.4 0.1 2.8 2 1 1 3 3 3 1 Ubiquitin-like domain Rad60-SLD PF11976.8 RLN26123.1 - 0.0032 17.3 0.0 0.007 16.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 RLN26123.1 - 0.0044 17.1 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-BED PF02892.15 RLN26123.1 - 0.053 13.6 1.3 0.16 12.0 1.3 1.7 1 0 0 1 1 1 0 BED zinc finger FXR_C1 PF16096.5 RLN26123.1 - 0.073 13.3 0.1 0.073 13.3 0.1 2.2 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Kinesin PF00225.23 RLN26124.1 - 1.2e-155 517.5 14.5 2.9e-94 315.7 0.1 4.4 3 2 1 4 4 4 2 Kinesin motor domain Microtub_bd PF16796.5 RLN26124.1 - 2.2e-17 63.4 0.0 1.7e-15 57.3 0.0 3.0 2 0 0 2 2 2 1 Microtubule binding Pertussis_S2S3 PF02918.15 RLN26124.1 - 0.048 13.6 0.0 12 5.8 0.0 2.7 2 0 0 2 2 2 0 Pertussis toxin, subunit 2 and 3, C-terminal domain Ank_4 PF13637.6 RLN26195.1 - 3.2e-40 136.0 23.8 2.8e-06 27.8 0.1 10.1 6 2 5 11 11 11 11 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN26195.1 - 5.9e-36 122.9 13.9 8.4e-09 35.9 0.3 6.0 4 1 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN26195.1 - 6.8e-33 112.3 24.9 0.0041 17.4 0.0 14.5 2 2 13 15 15 15 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN26195.1 - 1e-24 83.9 4.4 8.4 7.3 0.0 14.6 14 1 1 15 15 15 4 Ankyrin repeat DUF5049 PF16468.5 RLN26195.1 - 8.1e-05 22.4 0.0 9.8 6.2 0.0 6.8 7 2 1 8 8 8 1 Domain of unknown function (DUF5049) Ank PF00023.30 RLN26195.1 - 0.00049 20.4 3.4 98 3.7 0.1 8.7 4 2 1 5 5 5 0 Ankyrin repeat DUF4388 PF14332.6 RLN26195.1 - 0.014 15.6 0.1 25 5.2 0.0 4.3 5 1 1 6 6 6 0 Domain of unknown function (DUF4388) cNMP_binding PF00027.29 RLN26196.1 - 1.9e-19 69.5 0.0 3.4e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Glyco_hydro_17 PF00332.18 RLN26197.1 - 0.00036 20.2 0.0 0.012 15.2 0.0 2.5 1 1 2 3 3 3 2 Glycosyl hydrolases family 17 MoCF_biosynth PF00994.24 RLN26198.1 - 3.8e-13 49.3 0.1 6.6e-13 48.6 0.1 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Anp1 PF03452.14 RLN26199.1 - 1.7e-46 158.8 0.2 3.6e-46 157.7 0.2 1.4 1 1 0 1 1 1 1 Anp1 HR1 PF02185.16 RLN26200.1 - 5.8 7.1 7.2 0.4 10.8 1.3 2.1 2 0 0 2 2 2 0 Hr1 repeat fn3 PF00041.21 RLN26202.1 - 1.7e-40 137.3 0.0 3e-07 30.7 0.1 6.7 6 0 0 6 6 6 6 Fibronectin type III domain WD40 PF00400.32 RLN26202.1 - 5.4e-22 77.7 8.4 1e-06 29.4 0.7 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Pur_ac_phosph_N PF16656.5 RLN26202.1 - 5e-07 30.2 0.1 0.14 12.7 0.0 5.0 4 1 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain ANAPC4_WD40 PF12894.7 RLN26202.1 - 0.00035 20.8 0.3 1.6 9.1 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_S10 PF00450.22 RLN26205.1 - 1.5e-26 93.8 0.0 1.6e-26 93.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF1968 PF09291.10 RLN26205.1 - 0.059 13.4 0.4 0.14 12.3 0.5 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1968) Suf PF05843.14 RLN26207.1 - 2.3e-11 44.2 3.8 0.0002 21.4 0.0 5.6 4 1 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 RLN26207.1 - 1.5e-08 34.7 23.7 0.7 10.9 0.0 11.6 9 3 4 13 13 12 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN26207.1 - 3.3e-08 33.1 0.2 2 8.9 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 RLN26207.1 - 2.7e-07 30.6 5.6 0.37 10.8 0.0 6.6 7 2 0 7 7 7 2 Mad3/BUB1 homology region 1 NRDE-2 PF08424.10 RLN26207.1 - 6.4e-06 25.5 7.8 0.77 8.8 0.0 5.6 1 1 2 5 5 5 2 NRDE-2, necessary for RNA interference TPR_2 PF07719.17 RLN26207.1 - 1.6e-05 24.7 4.2 2.5 8.4 0.0 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN26207.1 - 1.8e-05 24.9 0.4 9.7 6.6 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 RLN26207.1 - 0.00034 19.9 3.1 0.33 10.1 0.4 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN26207.1 - 0.0012 18.7 1.0 2.4 8.4 0.0 5.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN26207.1 - 0.078 13.6 1.9 47 4.8 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat MerR_1 PF13411.6 RLN26207.1 - 0.08 13.0 0.1 6 7.0 0.0 2.7 2 0 0 2 2 2 0 MerR HTH family regulatory protein Pox_Ag35 PF03286.14 RLN26207.1 - 3.9 7.2 6.2 1.9 8.3 1.0 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FAM176 PF14851.6 RLN26207.1 - 5.9 6.5 7.4 24 4.5 0.3 2.5 2 0 0 2 2 2 0 FAM176 family DapB_C PF05173.14 RLN26208.1 - 5.2e-29 100.7 0.0 1.1e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus Aminotran_1_2 PF00155.21 RLN26208.1 - 3.3e-10 39.7 0.0 7.7e-10 38.5 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II DapB_N PF01113.20 RLN26208.1 - 1.9e-07 31.2 0.1 8.8e-06 25.9 0.1 2.5 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus CTP_transf_1 PF01148.20 RLN26209.1 - 5.9e-11 42.6 7.3 1.4e-10 41.4 7.3 1.5 1 0 0 1 1 1 1 Cytidylyltransferase family DUF872 PF05915.12 RLN26209.1 - 0.019 15.1 0.9 1.4 9.1 0.1 3.1 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) zf-MYND PF01753.18 RLN26210.1 - 1e-09 38.3 20.9 1.9e-09 37.4 20.9 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 RLN26210.1 - 6.2 7.2 14.4 13 6.2 14.4 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Epimerase PF01370.21 RLN26211.1 - 1.2e-53 182.1 0.0 1.5e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RLN26211.1 - 5.8e-14 52.2 0.0 2.8e-12 46.7 0.0 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 RLN26211.1 - 5.7e-08 32.2 0.0 1.8e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RLN26211.1 - 1.5e-05 24.3 0.0 0.28 10.3 0.0 3.1 3 0 0 3 3 3 3 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 RLN26211.1 - 0.0048 15.9 0.0 0.012 14.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GSHPx PF00255.19 RLN26212.1 - 5.6e-30 103.1 0.2 1.7e-26 91.9 0.1 2.2 2 0 0 2 2 2 2 Glutathione peroxidase AhpC-TSA PF00578.21 RLN26212.1 - 0.0051 16.7 0.0 0.0095 15.8 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family ASH PF15780.5 RLN26213.1 - 9.4e-18 64.2 0.3 1.1e-16 60.8 0.1 2.8 2 1 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CH PF00307.31 RLN26213.1 - 1.9e-16 60.2 0.2 4.1e-06 26.9 0.0 4.3 4 0 0 4 4 4 3 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RLN26213.1 - 5.9e-06 26.0 0.7 0.00035 20.3 0.1 4.1 4 0 0 4 4 4 1 CAMSAP CH domain Ribosomal_60s PF00428.19 RLN26214.1 - 1.3e-15 57.8 4.1 1.9e-15 57.2 4.1 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Prog_receptor PF02161.15 RLN26214.1 - 0.024 13.4 1.7 0.032 13.0 1.7 1.1 1 0 0 1 1 1 0 Progesterone receptor DUF3490 PF11995.8 RLN26215.1 - 0.26 11.1 0.9 1 9.2 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3490) MAP17 PF15807.5 RLN26215.1 - 0.43 10.8 3.0 0.63 10.3 0.4 2.6 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Gly-zipper_YMGG PF13441.6 RLN26215.1 - 3 7.7 8.4 7.3 6.4 8.4 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper adh_short_C2 PF13561.6 RLN26216.1 - 2e-50 171.6 3.0 2.4e-50 171.3 3.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RLN26216.1 - 1.2e-45 155.4 2.2 1.5e-45 155.1 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RLN26216.1 - 6.6e-11 42.4 0.8 9.3e-11 42.0 0.8 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 RLN26216.1 - 1.9e-05 24.0 0.0 2.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Pyr_redox PF00070.27 RLN26216.1 - 0.00063 20.3 0.3 0.003 18.1 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 RLN26216.1 - 0.0011 18.5 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RLN26216.1 - 0.0047 16.4 0.5 0.011 15.2 0.5 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 RLN26216.1 - 0.0087 16.5 0.2 0.018 15.5 0.2 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding SIS PF01380.22 RLN26216.1 - 0.027 14.3 0.1 0.049 13.5 0.1 1.5 1 0 0 1 1 1 0 SIS domain Pyr_redox_2 PF07992.14 RLN26216.1 - 0.05 12.8 1.1 0.21 10.8 0.7 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 RLN26216.1 - 0.079 12.3 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 RLN26216.1 - 0.091 11.8 0.3 0.19 10.8 0.3 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain 3HCDH_N PF02737.18 RLN26216.1 - 0.42 10.5 3.6 0.28 11.0 1.2 2.0 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AMP-binding PF00501.28 RLN26217.1 - 1.6e-63 214.8 0.0 2.9e-63 213.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 RLN26217.1 - 2.4e-59 201.2 0.0 1.5e-58 198.6 0.0 2.0 1 1 0 1 1 1 1 Condensation domain Thioesterase PF00975.20 RLN26217.1 - 1.6e-17 64.4 0.0 4.6e-17 62.9 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 RLN26217.1 - 1.1e-06 28.8 0.2 4.2e-06 27.0 0.1 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 RLN26217.1 - 7.2e-06 26.9 0.0 1.9e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydrolase_6 PF12697.7 RLN26217.1 - 0.055 14.1 4.9 0.059 14.0 0.7 3.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family F-box-like PF12937.7 RLN26222.1 - 0.0054 16.6 2.0 0.011 15.6 2.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RLN26222.1 - 0.013 15.4 0.4 0.025 14.5 0.4 1.5 1 0 0 1 1 1 0 F-box domain DUF2052 PF09747.9 RLN26222.1 - 0.04 14.0 5.2 0.058 13.5 5.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DNA_pol_phi PF04931.13 RLN26222.1 - 8.1 4.4 13.6 11 4.0 13.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 RLN26222.1 - 9.5 5.9 11.1 14 5.4 11.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MKT1_C PF12246.8 RLN26223.1 - 0.18 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication DM PF00751.18 RLN26227.1 - 0.098 12.6 0.8 0.21 11.5 0.8 1.6 1 0 0 1 1 1 0 DM DNA binding domain CCT PF06203.14 RLN26228.1 - 3.7e-15 55.7 6.8 4.4e-15 55.5 6.8 1.1 1 0 0 1 1 1 1 CCT motif REJ PF02010.15 RLN26229.1 - 2e-69 234.6 7.6 2.7e-62 211.1 6.1 2.8 1 1 1 2 2 2 2 REJ domain GPS PF01825.21 RLN26229.1 - 1.4e-09 38.3 3.3 4e-09 36.8 3.3 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif TMEM154 PF15102.6 RLN26229.1 - 0.00035 20.5 0.1 0.00035 20.5 0.1 2.9 2 0 0 2 2 2 1 TMEM154 protein family EGF_2 PF07974.13 RLN26229.1 - 0.044 14.2 10.0 0.099 13.0 10.0 1.7 1 0 0 1 1 1 0 EGF-like domain Curto_V3 PF07436.11 RLN26229.1 - 0.095 13.1 1.4 1.7 9.1 0.4 3.0 2 0 0 2 2 2 0 Curtovirus V3 protein DUF1640 PF07798.11 RLN26234.1 - 0.12 12.4 1.6 0.22 11.6 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Motile_Sperm PF00635.26 RLN26234.1 - 0.21 11.4 1.2 6.2 6.7 0.0 3.7 4 0 0 4 4 4 0 MSP (Major sperm protein) domain NARP1 PF12569.8 RLN26235.1 - 1.2 7.9 6.3 1.9 7.3 6.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ASH PF15780.5 RLN26236.1 - 8.4e-11 41.9 6.1 0.0012 19.1 0.1 5.8 6 0 0 6 6 6 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 RLN26236.1 - 0.1 12.6 3.6 2.1 8.4 0.6 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1573) HSF_DNA-bind PF00447.17 RLN26239.1 - 1.5e-21 76.8 1.4 2.2e-21 76.3 1.4 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding DUF1484 PF07363.11 RLN26240.1 - 1.3 10.1 7.2 2.3 9.3 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) E1-E2_ATPase PF00122.20 RLN26249.1 - 4.1e-47 160.0 3.6 8.5e-31 106.9 0.3 2.5 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase PF13246.6 RLN26249.1 - 1.7e-18 66.5 0.0 2e-17 63.1 0.0 2.5 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 RLN26249.1 - 3.4e-16 58.7 0.0 7.6e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 RLN26249.1 - 1.5e-09 38.5 0.2 1.5e-05 25.4 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF998 PF06197.13 RLN26249.1 - 0.051 13.2 3.5 0.082 12.5 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF998) PX PF00787.24 RLN26250.1 - 0.0018 18.3 0.1 0.0045 16.9 0.1 1.7 1 1 0 1 1 1 1 PX domain Adeno_E3A PF05248.12 RLN26250.1 - 0.0037 17.2 1.1 0.0083 16.1 1.1 1.6 1 0 0 1 1 1 1 Adenovirus E3A Glycos_transf_1 PF00534.20 RLN26251.1 - 0.00011 21.8 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RLN26251.1 - 0.0023 18.4 0.0 0.0053 17.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 RLN26252.1 - 0.00055 19.5 0.0 0.0016 18.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RLN26252.1 - 0.013 16.0 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 RLN26253.1 - 0.09 12.3 0.0 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 RLN26254.1 - 0.21 11.1 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 EamA PF00892.20 RLN26269.1 - 1.2e-17 64.4 34.2 8.6e-10 38.9 3.7 3.1 1 1 2 3 3 3 3 EamA-like transporter family EamA PF00892.20 RLN26270.1 - 4e-13 49.7 12.5 5.7e-13 49.2 12.5 1.2 1 0 0 1 1 1 1 EamA-like transporter family YbjM PF11045.8 RLN26270.1 - 0.022 14.9 2.9 0.05 13.8 0.3 2.2 2 0 0 2 2 2 0 Putative inner membrane protein of Enterobacteriaceae YjcZ PF13990.6 RLN26271.1 - 0.0083 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 YjcZ-like protein FYVE_2 PF02318.16 RLN26271.1 - 0.052 13.8 4.2 0.14 12.4 4.2 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 RLN26271.1 - 0.098 12.8 10.2 0.21 11.7 10.2 1.5 1 0 0 1 1 1 0 FYVE zinc finger Ras PF00071.22 RLN26272.1 - 2e-41 141.3 0.3 2.7e-41 140.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN26272.1 - 2e-31 108.7 0.2 2.9e-31 108.2 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN26272.1 - 1.3e-12 47.5 0.2 1.8e-12 47.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RLN26272.1 - 5.3e-05 22.7 0.1 7.5e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RLN26272.1 - 0.00041 20.4 0.0 0.00085 19.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RLN26272.1 - 0.0091 15.6 0.3 0.047 13.2 0.3 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain VHP PF02209.19 RLN26272.1 - 0.035 14.2 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 Villin headpiece domain PduV-EutP PF10662.9 RLN26272.1 - 0.038 13.7 0.2 0.084 12.6 0.2 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 RLN26272.1 - 0.059 12.9 0.1 0.059 12.9 0.1 1.5 2 0 0 2 2 2 0 Ferrous iron transport protein B cobW PF02492.19 RLN26272.1 - 0.062 12.9 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Ank_2 PF12796.7 RLN26275.1 - 1.1e-39 134.9 12.3 3.2e-09 37.2 0.1 6.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN26275.1 - 9.9e-35 114.6 10.5 0.00014 22.0 0.0 9.7 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 RLN26275.1 - 3.3e-33 112.7 21.8 4.7e-05 23.6 0.0 9.1 8 1 1 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 RLN26275.1 - 8.7e-31 105.9 11.6 1.9e-06 28.3 0.3 7.4 3 3 4 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN26275.1 - 2.6e-25 88.1 10.1 0.00033 20.9 0.0 7.2 5 2 2 7 7 7 6 Ankyrin repeats (many copies) RskA PF10099.9 RLN26276.1 - 0.02 15.2 0.6 0.02 15.2 0.6 2.4 2 1 0 2 2 2 0 Anti-sigma-K factor rskA UNC45-central PF11701.8 RLN26278.1 - 0.0048 16.9 1.3 0.039 13.9 0.1 2.8 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.6 RLN26278.1 - 0.0048 17.3 4.7 0.071 13.5 0.8 3.9 4 2 1 5 5 5 1 HEAT repeats FANCI_S2 PF14676.6 RLN26278.1 - 0.3 11.4 4.5 0.15 12.3 0.3 2.4 3 0 0 3 3 3 0 FANCI solenoid 2 cNMP_binding PF00027.29 RLN26279.1 - 1.9e-17 63.1 0.1 2.5e-09 37.1 0.1 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain EamA PF00892.20 RLN26280.1 - 8.6e-14 51.9 30.2 3.7e-11 43.4 17.2 2.5 2 1 0 2 2 2 2 EamA-like transporter family PPR_2 PF13041.6 RLN26282.1 - 2.2e-25 88.6 0.5 1.9e-05 24.8 0.0 7.4 3 1 4 7 7 7 5 PPR repeat family PPR PF01535.20 RLN26282.1 - 1e-18 66.2 0.7 0.048 13.9 0.0 9.0 10 0 0 10 10 10 4 PPR repeat PPR_3 PF13812.6 RLN26282.1 - 9e-17 60.9 0.0 7.9e-07 29.1 0.0 4.6 4 0 0 4 4 4 4 Pentatricopeptide repeat domain PPR_long PF17177.4 RLN26282.1 - 4e-11 42.7 3.7 0.00021 20.7 0.1 3.4 1 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP COX5A PF02284.16 RLN26282.1 - 4.2e-05 23.5 0.8 3.2 7.8 0.0 4.2 2 1 1 4 4 4 2 Cytochrome c oxidase subunit Va PPR_1 PF12854.7 RLN26282.1 - 0.00044 19.9 0.2 5.2 6.9 0.0 4.4 4 0 0 4 4 4 2 PPR repeat RPM2 PF08579.11 RLN26282.1 - 0.015 15.7 0.1 1.1 9.7 0.0 2.9 2 1 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) UCH PF00443.29 RLN26283.1 - 1.9e-67 227.5 0.0 2.5e-67 227.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN26283.1 - 1.5e-17 64.2 0.1 5.5e-10 39.3 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase EF-hand_7 PF13499.6 RLN26283.1 - 0.027 14.9 2.5 0.12 12.8 0.1 3.1 3 0 0 3 3 3 0 EF-hand domain pair CDC4_D PF16856.5 RLN26283.1 - 0.12 12.3 0.1 3.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Cell division control protein 4 dimerisation domain Plexin_cytopl PF08337.12 RLN26283.1 - 0.23 10.1 0.4 0.38 9.4 0.4 1.3 1 0 0 1 1 1 0 Plexin cytoplasmic RasGAP domain IQ PF00612.27 RLN26297.1 - 3.3e-13 48.2 123.0 0.00047 19.7 1.0 17.0 14 3 3 17 17 17 10 IQ calmodulin-binding motif MSA_2 PF00985.17 RLN26297.1 - 0.21 11.9 0.0 0.4 11.0 0.0 1.4 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family DUF1100 PF06500.11 RLN26302.1 - 0.13 11.0 0.0 0.14 11.0 0.0 1.0 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) PDEase_I PF00233.19 RLN26325.1 - 9.1e-66 222.0 1.6 1.1e-65 221.7 1.6 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Phage_tail_T PF06223.12 RLN26326.1 - 0.11 13.1 0.3 0.26 11.8 0.3 1.6 1 0 0 1 1 1 0 Minor tail protein T OmpA PF00691.20 RLN26326.1 - 0.14 12.6 0.2 0.34 11.3 0.2 1.6 1 0 0 1 1 1 0 OmpA family Glyco_hydro_3 PF00933.21 RLN26328.1 - 8.7e-49 166.6 0.0 1.1e-48 166.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN26328.1 - 4.5e-18 65.9 0.0 3e-17 63.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Prenyltrans PF00432.21 RLN26330.1 - 2.1e-58 193.7 16.4 8.3e-14 51.0 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 RLN26330.1 - 5e-06 25.8 0.0 0.002 17.3 0.0 3.3 2 2 3 5 5 5 4 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 RLN26330.1 - 1.6e-05 24.2 0.0 0.0017 17.5 0.0 2.9 2 1 1 3 3 3 1 Squalene-hopene cyclase C-terminal domain Proteasome PF00227.26 RLN26331.1 - 1.8e-27 96.0 2.5 1.2e-18 67.2 0.0 2.4 2 1 0 2 2 2 2 Proteasome subunit Cupin_2 PF07883.11 RLN26352.1 - 1.1e-07 31.4 0.6 0.00027 20.6 0.1 2.6 3 0 0 3 3 3 2 Cupin domain Cupin_1 PF00190.22 RLN26352.1 - 0.0019 17.8 0.2 0.031 13.9 0.0 2.2 2 0 0 2 2 2 1 Cupin CENP-C_C PF11699.8 RLN26352.1 - 0.057 13.6 0.5 0.18 12.0 0.1 2.0 2 1 0 2 2 2 0 Mif2/CENP-C like Histone_H2A_C PF16211.5 RLN26352.1 - 0.2 11.4 1.0 0.55 10.0 0.1 2.1 2 0 0 2 2 2 0 C-terminus of histone H2A SNARE PF05739.19 RLN26353.1 - 0.0012 18.8 0.9 0.0079 16.2 0.1 2.4 2 0 0 2 2 2 1 SNARE domain DUF1664 PF07889.12 RLN26353.1 - 0.0027 17.7 7.6 0.075 13.1 1.7 3.1 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) MCPsignal PF00015.21 RLN26353.1 - 0.004 17.0 7.9 0.0056 16.5 6.4 2.0 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain SKA1 PF07160.12 RLN26353.1 - 0.0041 17.0 1.2 0.0041 17.0 1.2 1.7 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 1 Syntaxin_2 PF14523.6 RLN26353.1 - 0.017 15.5 5.1 2.2 8.7 0.6 2.5 2 1 0 2 2 2 0 Syntaxin-like protein FlaC_arch PF05377.11 RLN26353.1 - 0.025 15.0 1.2 0.11 12.9 0.2 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Trimer_CC PF08954.11 RLN26353.1 - 0.028 14.0 0.2 0.028 14.0 0.2 2.3 3 0 0 3 3 3 0 Trimerisation motif Phage_connect_1 PF05135.13 RLN26353.1 - 0.069 13.7 0.3 0.22 12.0 0.1 2.0 2 1 0 2 2 2 0 Phage gp6-like head-tail connector protein RasGAP_C PF03836.15 RLN26353.1 - 0.13 12.4 2.0 0.25 11.5 2.0 1.5 1 0 0 1 1 1 0 RasGAP C-terminus DUF948 PF06103.11 RLN26353.1 - 0.15 12.3 2.6 2.7 8.3 1.4 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 RLN26353.1 - 0.17 10.7 9.0 0.28 10.0 9.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin PF00804.25 RLN26353.1 - 0.42 10.3 10.7 0.099 12.3 5.9 2.3 2 1 1 3 3 3 0 Syntaxin Fib_alpha PF08702.10 RLN26353.1 - 0.53 10.5 4.3 1.7 8.9 4.3 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 RLN26353.1 - 0.6 10.2 4.2 0.45 10.5 0.5 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 RLN26353.1 - 3.3 8.1 8.3 1.2 9.5 1.8 2.5 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC_tran_CTD PF16326.5 RLN26353.1 - 5.6 7.3 9.4 1.9 8.8 3.3 2.8 2 1 0 2 2 2 0 ABC transporter C-terminal domain HA2 PF04408.23 RLN26354.1 - 4.9e-23 81.5 0.1 2.1e-22 79.5 0.1 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RLN26354.1 - 1.4e-14 54.2 0.0 4.7e-14 52.5 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 RLN26354.1 - 5.7e-12 46.0 0.1 1.2e-11 45.0 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 RLN26354.1 - 9.7e-06 25.9 0.0 3.2e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 RLN26354.1 - 1.2e-05 25.2 0.0 2.8e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 RLN26354.1 - 0.0016 18.8 0.0 0.0048 17.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RLN26354.1 - 0.0053 16.5 0.1 0.016 14.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 RLN26354.1 - 0.02 13.9 0.0 0.04 13.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 RLN26354.1 - 0.047 13.2 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 RLN26354.1 - 0.1 13.0 3.9 0.21 11.9 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain PhoH PF02562.16 RLN26354.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 RLN26354.1 - 0.2 12.2 0.1 1.7 9.1 0.1 2.4 1 1 0 1 1 1 0 ABC transporter LRR_8 PF13855.6 RLN26355.1 - 2.3e-10 40.1 6.3 2.6e-06 27.1 0.0 3.9 3 1 1 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 RLN26355.1 - 9.6e-09 35.0 0.2 0.00029 20.4 0.0 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 RLN26355.1 - 2.3e-08 34.2 3.6 0.0051 17.2 0.0 4.1 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) PKcGMP_CC PF16808.5 RLN26355.1 - 2.7 7.9 7.0 1.6 8.6 1.3 3.4 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TMPIT PF07851.13 RLN26355.1 - 3.6 6.8 4.5 5 6.3 3.9 1.5 1 1 0 1 1 1 0 TMPIT-like protein LRR_1 PF00560.33 RLN26355.1 - 6.6 7.7 6.2 39 5.3 1.0 4.1 3 1 0 3 3 3 0 Leucine Rich Repeat PUNUT PF16913.5 RLN26356.1 - 0.00066 19.0 10.6 0.0011 18.3 10.6 1.3 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 RLN26356.1 - 0.0022 18.1 22.4 0.055 13.6 4.4 3.5 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 RLN26356.1 - 0.0025 17.0 0.4 0.0084 15.3 0.2 1.8 1 1 0 1 1 1 1 Nucleotide-sugar transporter TMEM234 PF10639.9 RLN26356.1 - 0.015 15.3 3.0 0.029 14.4 0.2 2.2 2 0 0 2 2 2 0 Putative transmembrane family 234 TPT PF03151.16 RLN26356.1 - 0.057 12.8 9.3 0.043 13.2 2.1 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family DnaJ PF00226.31 RLN26358.1 - 6.3e-12 45.5 2.7 1.1e-11 44.7 0.8 2.0 1 1 1 2 2 2 1 DnaJ domain G_glu_transpept PF01019.21 RLN26366.1 - 6.5e-140 467.3 0.1 9.1e-140 466.8 0.1 1.2 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Snf7 PF03357.21 RLN26366.1 - 0.0021 17.7 6.6 0.0021 17.7 6.6 2.8 2 1 0 2 2 2 1 Snf7 API5 PF05918.11 RLN26366.1 - 0.018 13.9 1.3 0.025 13.4 1.3 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF4407 PF14362.6 RLN26366.1 - 0.067 12.5 0.3 0.12 11.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF21 PF01595.20 RLN26368.1 - 2.1e-32 112.3 1.2 3.5e-32 111.5 1.2 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 RLN26368.1 - 6.1e-05 23.4 2.6 0.035 14.5 0.4 3.2 2 1 0 2 2 2 2 CBS domain EF-hand_1 PF00036.32 RLN26369.1 - 1.5e-08 33.6 0.1 0.0037 16.7 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RLN26369.1 - 1.7e-07 31.6 0.1 3.1e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN26369.1 - 2.1e-05 24.1 0.0 0.012 15.5 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RLN26369.1 - 7.9e-05 22.0 0.2 0.3 10.6 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RLN26369.1 - 0.0012 18.7 0.3 1.4 8.8 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair Peptidase_A22B PF04258.13 RLN26370.1 - 8.8e-87 291.2 8.0 1.2e-86 290.7 8.0 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 RLN26370.1 - 5.7e-05 22.7 1.7 5.7e-05 22.7 1.7 3.0 2 1 1 3 3 3 2 Signal-peptide peptidase, presenilin aspartyl protease ParBc PF02195.18 RLN26371.1 - 7.2e-08 32.6 0.0 0.014 15.6 0.0 2.6 2 0 0 2 2 2 2 ParB-like nuclease domain DUF1015 PF06245.11 RLN26371.1 - 0.0061 15.5 0.1 2 7.2 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF1015) DUF883 PF05957.13 RLN26371.1 - 2 9.1 4.7 0.93 10.1 0.8 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF21 PF01595.20 RLN26372.1 - 4.3e-33 114.5 0.9 4.3e-33 114.5 0.9 1.6 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 RLN26372.1 - 0.0054 17.2 2.4 6.5 7.3 0.1 3.6 3 1 0 3 3 3 2 CBS domain Peptidase_M14 PF00246.24 RLN26373.1 - 2.5e-39 135.8 0.0 3.7e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase SHIPPO-rpt PF07004.12 RLN26373.1 - 0.0006 20.6 0.9 0.52 11.3 0.1 3.0 2 0 0 2 2 2 2 Sperm-tail PG-rich repeat BP28CT PF08146.12 RLN26374.1 - 1.5e-44 151.6 0.2 1.5e-44 151.6 0.2 3.3 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 RLN26374.1 - 2.4e-19 69.8 3.0 2.4e-19 69.8 3.0 6.3 8 0 0 8 8 8 1 U3 small nucleolar RNA-associated protein 10 HEAT_EZ PF13513.6 RLN26374.1 - 8e-07 29.4 2.9 0.034 14.7 0.0 7.1 4 1 1 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.6 RLN26374.1 - 1.4e-05 25.4 18.9 4.1 7.8 0.0 8.6 9 1 1 10 10 10 3 HEAT repeats Cnd1 PF12717.7 RLN26374.1 - 0.00014 22.0 21.8 2.3 8.2 0.0 7.6 6 1 2 8 8 8 4 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RLN26374.1 - 0.016 15.4 0.4 0.016 15.4 0.4 7.2 8 0 0 8 8 8 0 HEAT repeat HMGL-like PF00682.19 RLN26375.1 - 3.3e-06 26.9 0.0 0.014 15.0 0.0 2.2 2 0 0 2 2 2 2 HMGL-like PEX11 PF05648.14 RLN26376.1 - 1.8e-10 40.7 0.0 2.1e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Phage_TAC_11 PF11836.8 RLN26376.1 - 0.11 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Phage tail tube protein, GTA-gp10 PI3_PI4_kinase PF00454.27 RLN26377.1 - 9.2e-37 127.2 0.2 5.4e-34 118.1 0.2 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 RLN26377.1 - 2.4e-06 27.1 0.5 4.5e-06 26.2 0.5 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 RLN26377.1 - 0.042 13.2 0.0 0.088 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) UPF0242 PF06785.11 RLN26379.1 - 0.0017 18.5 6.8 0.0025 18.0 6.8 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 RLN26379.1 - 0.0026 18.0 7.0 0.0031 17.7 7.0 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Med14 PF08638.11 RLN26379.1 - 0.031 13.7 1.2 0.04 13.3 1.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit MED14 ZapB PF06005.12 RLN26379.1 - 0.052 14.0 7.1 0.052 14.0 7.1 2.1 1 1 1 2 2 2 0 Cell division protein ZapB DUF3552 PF12072.8 RLN26379.1 - 0.11 11.9 10.5 0.16 11.3 10.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) MetOD2 PF18548.1 RLN26379.1 - 0.29 11.3 4.9 0.54 10.4 3.8 1.9 2 0 0 2 2 2 0 Metanogen output domain 2 BRE1 PF08647.11 RLN26379.1 - 0.38 10.9 14.1 0.098 12.7 11.3 1.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase KxDL PF10241.9 RLN26379.1 - 0.78 10.1 10.9 2.1 8.7 4.3 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF5595 PF18077.1 RLN26379.1 - 1.1 9.4 4.5 1.3 9.1 1.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) ADIP PF11559.8 RLN26379.1 - 1.2 9.2 14.5 2.1 8.4 14.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding OmpH PF03938.14 RLN26379.1 - 1.9 8.8 11.4 3.4 8.0 11.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF16 PF01519.16 RLN26379.1 - 2.6 8.6 8.6 4.3 7.9 8.5 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 YabA PF06156.13 RLN26379.1 - 4.2 8.1 9.5 46 4.7 9.5 2.1 1 1 0 1 1 1 0 Initiation control protein YabA Stealth_CR2 PF11380.8 RLN26380.1 - 4.9e-46 155.4 0.0 1.6e-45 153.7 0.0 1.9 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR4 PF17103.5 RLN26380.1 - 1.7e-16 59.8 0.0 4.6e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Notch PF00066.17 RLN26380.1 - 5.5e-15 55.5 27.8 1.2e-07 32.0 9.1 2.5 2 0 0 2 2 2 2 LNR domain Stealth_CR3 PF17102.5 RLN26380.1 - 1.7e-14 53.4 4.3 1.7e-14 53.4 4.3 2.4 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 RLN26380.1 - 3.8e-11 42.5 2.0 2.4e-10 39.9 2.3 2.2 2 0 0 2 2 2 1 Stealth protein CR1, conserved region 1 DUF2892 PF11127.8 RLN26380.1 - 0.13 12.3 3.2 1.1 9.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) DUF647 PF04884.14 RLN26381.1 - 2.1e-73 247.0 5.6 2.8e-73 246.5 5.6 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Pkinase PF00069.25 RLN26382.1 - 9.6e-51 172.7 0.0 1.9e-50 171.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN26382.1 - 4.7e-19 68.7 0.0 7e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN26382.1 - 7.5e-06 25.5 0.0 1.3e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN26382.1 - 0.071 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_TAC_6 PF09550.10 RLN26382.1 - 0.12 12.9 0.1 0.37 11.2 0.1 1.8 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC Seadorna_VP7 PF07387.11 RLN26382.1 - 0.14 11.1 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 PH PF00169.29 RLN26383.1 - 0.0007 20.1 0.0 0.0011 19.4 0.0 1.3 1 0 0 1 1 1 1 PH domain Bac_DNA_binding PF00216.21 RLN26384.1 - 2.7e-05 24.3 0.1 7.3e-05 22.9 0.0 1.6 1 1 1 2 2 2 1 Bacterial DNA-binding protein HU-CCDC81_bac_2 PF18175.1 RLN26384.1 - 0.0024 17.7 0.0 0.0035 17.2 0.0 1.2 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 AAA_lid_7 PF17867.1 RLN26384.1 - 0.085 13.1 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Midasin AAA lid domain Elicitin PF00964.17 RLN26396.1 - 9.4e-24 83.3 7.3 1.6e-23 82.6 7.3 1.4 1 0 0 1 1 1 1 Elicitin PT PF04886.12 RLN26396.1 - 5.9e-06 25.7 18.8 5.9e-06 25.7 18.8 1.9 2 0 0 2 2 2 1 PT repeat ANF_receptor PF01094.28 RLN26396.1 - 1 8.4 4.7 1.5 7.9 4.7 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region Elicitin PF00964.17 RLN26397.1 - 5.3e-21 74.5 3.3 5.3e-21 74.5 3.3 2.2 2 0 0 2 2 2 1 Elicitin Elicitin PF00964.17 RLN26398.1 - 1.6e-22 79.4 2.1 1.6e-22 79.4 2.1 2.3 2 1 0 2 2 2 1 Elicitin Mucin PF01456.17 RLN26398.1 - 0.35 10.9 42.8 0.074 13.0 38.2 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein Elicitin PF00964.17 RLN26399.1 - 8e-24 83.6 5.8 1.1e-23 83.1 5.8 1.2 1 0 0 1 1 1 1 Elicitin Elicitin PF00964.17 RLN26400.1 - 2.4e-40 136.5 5.1 8.3e-22 77.1 1.5 2.2 2 0 0 2 2 2 2 Elicitin PT PF04886.12 RLN26400.1 - 0.00016 21.2 35.0 0.00017 21.0 30.6 3.3 3 1 0 3 3 3 1 PT repeat FAD-SLDH PF12318.8 RLN26400.1 - 0.011 15.8 0.2 1.2 9.2 0.1 2.2 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF373 PF04123.13 RLN26400.1 - 0.029 13.8 2.4 3.6 6.9 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF373) HTH_51 PF18558.1 RLN26400.1 - 0.043 13.7 0.0 12 5.9 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain UPF0231 PF06062.11 RLN26400.1 - 0.1 12.8 0.1 21 5.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0231) Elicitin PF00964.17 RLN26401.1 - 2.9e-24 85.0 8.1 3.7e-24 84.6 8.1 1.1 1 0 0 1 1 1 1 Elicitin ANF_receptor PF01094.28 RLN26401.1 - 0.5 9.4 4.7 0.64 9.1 4.7 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region Elicitin PF00964.17 RLN26402.1 - 8.4e-24 83.5 6.6 1e-23 83.2 6.6 1.1 1 0 0 1 1 1 1 Elicitin Elicitin PF00964.17 RLN26403.1 - 1.8e-24 85.6 8.2 2.3e-24 85.3 8.2 1.1 1 0 0 1 1 1 1 Elicitin ANF_receptor PF01094.28 RLN26403.1 - 0.49 9.4 4.6 0.67 9.0 4.6 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region Elicitin PF00964.17 RLN26404.1 - 2.9e-24 85.0 8.2 3.6e-24 84.7 8.2 1.1 1 0 0 1 1 1 1 Elicitin ANF_receptor PF01094.28 RLN26404.1 - 0.5 9.4 4.7 0.64 9.1 4.7 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region Herpes_LP PF03363.13 RLN26416.1 - 0.018 14.8 0.6 0.023 14.5 0.6 1.1 1 0 0 1 1 1 0 Herpesvirus leader protein Aminotran_4 PF01063.19 RLN26416.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Amino-transferase class IV WD40 PF00400.32 RLN26417.1 - 4.3e-43 144.5 14.8 2.4e-08 34.5 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 RLN26417.1 - 4.5e-22 78.2 6.5 6.7e-22 77.6 6.5 1.3 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 RLN26417.1 - 8.1e-14 51.7 0.0 7.9e-06 26.1 0.0 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN26417.1 - 1.1e-06 27.8 0.3 0.22 10.5 0.0 3.9 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 RLN26417.1 - 0.00087 18.7 0.9 0.37 10.1 0.0 3.3 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 RLN26417.1 - 0.0032 16.2 1.3 0.096 11.3 0.0 2.9 2 1 1 3 3 3 1 Nucleoporin Nup120/160 PD40 PF07676.12 RLN26417.1 - 0.0058 16.5 0.1 9.7 6.3 0.0 3.6 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 RLN26417.1 - 0.0077 15.6 0.0 4.9 6.4 0.0 2.6 2 1 1 3 3 3 2 WD40-like domain Golgin_A5 PF09787.9 RLN26417.1 - 0.018 14.5 2.4 0.03 13.8 2.4 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Cluap1 PF10234.9 RLN26417.1 - 0.05 13.0 4.1 0.076 12.4 4.1 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 TSNAXIP1_N PF15739.5 RLN26417.1 - 0.093 13.1 4.7 0.19 12.1 4.7 1.4 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus DUF3450 PF11932.8 RLN26417.1 - 0.4 9.9 6.6 0.93 8.7 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GAS PF13851.6 RLN26417.1 - 1.4 8.3 8.6 2.1 7.6 8.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ISG65-75 PF11727.8 RLN26418.1 - 0.013 14.8 6.4 0.019 14.2 6.4 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein DivIC PF04977.15 RLN26418.1 - 0.022 14.5 4.7 0.022 14.5 4.7 2.7 1 1 2 3 3 3 0 Septum formation initiator SOGA PF11365.8 RLN26418.1 - 0.076 14.2 0.5 0.076 14.2 0.5 3.2 2 1 1 3 3 3 0 Protein SOGA ERM PF00769.19 RLN26418.1 - 0.15 11.9 30.6 0.069 13.0 24.2 2.1 1 1 0 2 2 2 0 Ezrin/radixin/moesin family TMCO5 PF14992.6 RLN26418.1 - 0.48 10.0 11.0 0.28 10.7 6.6 2.0 1 1 1 2 2 2 0 TMCO5 family AAA_13 PF13166.6 RLN26418.1 - 0.68 8.5 8.4 0.8 8.3 8.4 1.1 1 0 0 1 1 1 0 AAA domain DUF5340 PF17275.2 RLN26418.1 - 0.91 9.7 8.3 0.17 12.0 4.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5340) ATG16 PF08614.11 RLN26418.1 - 1.4 9.1 24.8 2.2 8.4 24.8 1.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.19 RLN26418.1 - 1.5 6.6 4.3 1.7 6.4 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-H PF05837.12 RLN26418.1 - 2.2 8.7 22.8 2.2 8.7 3.4 2.8 1 1 2 3 3 3 0 Centromere protein H (CENP-H) TMF_TATA_bd PF12325.8 RLN26418.1 - 3.1 8.1 18.5 2.4 8.4 8.0 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4200 PF13863.6 RLN26418.1 - 3.5 8.1 17.9 1.3 9.5 13.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF724 PF05266.14 RLN26418.1 - 9.8 6.0 12.8 4.9 6.9 9.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DnaGprimase_HBD PF16730.5 RLN26419.1 - 0.016 15.3 0.3 4.5 7.4 0.0 2.4 2 0 0 2 2 2 0 DnaG-primase C-terminal, helicase-binding domain Halogen_Hydrol PF10112.9 RLN26419.1 - 0.02 14.9 1.0 0.16 12.0 0.1 2.7 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF445 PF04286.12 RLN26419.1 - 0.024 14.5 9.6 0.033 14.0 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF445) RTTN_N PF14726.6 RLN26419.1 - 0.061 14.1 0.8 0.18 12.7 0.8 1.8 1 0 0 1 1 1 0 Rotatin, an armadillo repeat protein, centriole functioning DnaI_N PF07319.11 RLN26419.1 - 0.25 12.0 2.2 41 4.9 0.1 3.5 2 2 0 2 2 2 0 Primosomal protein DnaI N-terminus MFS_4 PF06779.14 RLN26419.1 - 0.8 8.9 2.2 21 4.3 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB T6PP_N PF18572.1 RLN26419.1 - 2.2 8.2 9.6 23 4.9 0.1 3.9 2 1 0 3 3 3 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain GST_N_2 PF13409.6 RLN26420.1 - 1e-11 45.0 0.0 1.4e-10 41.3 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 RLN26420.1 - 2.8e-10 40.5 0.0 1.2e-05 25.6 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RLN26420.1 - 8.7e-09 35.6 0.3 7.4e-05 23.0 0.0 3.3 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN26420.1 - 0.01 15.8 0.1 0.024 14.7 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HTH_Tnp_Tc5 PF03221.16 RLN26421.1 - 0.0094 16.0 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Nucleoporin_FG PF13634.6 RLN26422.1 - 1.5e-12 48.2 46.7 0.00024 21.9 0.6 8.4 5 2 4 9 9 9 7 Nucleoporin FG repeat region AAA_33 PF13671.6 RLN26423.1 - 1.9e-19 70.2 0.0 1.1e-18 67.8 0.0 2.3 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 RLN26423.1 - 8.5e-09 35.0 0.2 1.4e-07 31.0 0.1 2.6 2 1 0 2 2 2 1 Zeta toxin CPT PF07931.12 RLN26423.1 - 0.00024 21.0 0.0 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 RLN26423.1 - 0.0036 17.7 0.0 0.0084 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RLN26423.1 - 0.009 16.6 0.0 0.05 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 RLN26423.1 - 0.023 14.6 0.0 0.07 13.0 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase PCSK9_C3 PF18463.1 RLN26423.1 - 0.21 11.8 0.7 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Ank_2 PF12796.7 RLN26424.1 - 4e-31 107.5 8.0 1.4e-11 44.8 0.3 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN26424.1 - 2.3e-20 72.7 3.4 3.1e-09 37.2 0.3 5.8 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN26424.1 - 3e-19 67.1 4.9 0.0014 18.9 0.1 7.6 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 RLN26424.1 - 2e-17 63.0 8.5 2.5e-07 30.8 0.2 4.9 4 2 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 RLN26424.1 - 3.5e-16 58.8 16.8 8.3e-05 22.9 0.1 7.7 7 1 1 8 8 8 4 Ankyrin repeat WD40 PF00400.32 RLN26425.1 - 6.1e-58 191.5 22.3 3.2e-08 34.1 0.5 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN26425.1 - 2.2e-15 56.7 0.1 0.00055 20.2 0.0 6.0 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN26425.1 - 2.5e-07 30.0 5.8 0.019 13.9 0.1 5.6 1 1 6 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 RLN26425.1 - 8.4e-05 22.5 0.0 0.00062 19.7 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 RLN26425.1 - 0.038 12.6 3.6 0.99 8.0 0.0 3.5 2 2 2 4 4 4 0 Nucleoporin Nup120/160 Na_H_Exchanger PF00999.21 RLN26428.1 - 2.4e-56 191.2 28.0 3e-56 190.9 28.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family zf-RING_2 PF13639.6 RLN26429.1 - 9.9e-12 45.0 8.4 1.9e-11 44.1 8.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RLN26429.1 - 8.4e-09 35.6 7.8 1.3e-08 34.9 7.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 RLN26429.1 - 3.6e-08 33.1 5.1 9.8e-08 31.7 5.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN26429.1 - 1.3e-07 31.2 1.5 2.8e-07 30.1 1.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 RLN26429.1 - 2.6e-06 27.2 3.7 2.6e-06 27.2 3.7 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN26429.1 - 4.9e-06 26.3 6.0 8e-06 25.6 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN26429.1 - 5.1e-06 26.4 1.9 1.1e-05 25.4 1.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 RLN26429.1 - 0.0013 18.8 4.1 0.0027 17.7 4.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 RLN26429.1 - 0.0015 18.4 3.6 0.0032 17.3 3.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 RINGv PF12906.7 RLN26429.1 - 0.0075 16.4 2.5 0.024 14.7 2.5 1.9 1 1 0 1 1 1 1 RING-variant domain zf-RING_5 PF14634.6 RLN26429.1 - 0.0087 16.0 6.0 0.017 15.1 6.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 RLN26429.1 - 0.023 14.8 3.3 0.043 13.9 3.3 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 RLN26429.1 - 0.042 14.0 6.2 0.042 14.0 6.2 2.4 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 RLN26429.1 - 0.058 13.2 5.6 0.11 12.2 5.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 RLN26429.1 - 0.14 12.4 5.3 0.32 11.2 5.3 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 RLN26429.1 - 1.7 9.0 6.9 3.5 8.0 6.7 1.7 1 1 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 RLN26429.1 - 2.8 7.7 7.4 7.5 6.3 7.4 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type MatE PF01554.18 RLN26430.1 - 6.9e-29 100.6 28.2 1.1e-23 83.7 11.6 2.4 2 0 0 2 2 2 2 MatE DUF5455 PF17537.2 RLN26430.1 - 0.036 14.5 2.0 0.036 14.5 2.0 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5455) Nckap1 PF09735.9 RLN26431.1 - 6.1e-41 140.4 0.0 3.7e-31 108.0 0.0 3.6 2 2 1 3 3 3 3 Membrane-associated apoptosis protein CesT PF05932.13 RLN26431.1 - 0.37 10.9 3.3 1.1 9.4 0.2 3.1 3 0 0 3 3 3 0 Tir chaperone protein (CesT) family K_channel_TID PF07941.11 RLN26431.1 - 1.7 9.1 4.4 0.98 9.9 0.6 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain LRR_8 PF13855.6 RLN26432.1 - 6.5e-05 22.6 5.4 0.0017 18.1 0.6 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RLN26432.1 - 0.00024 21.4 1.8 0.029 14.8 0.2 2.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN26432.1 - 0.0046 16.5 0.5 0.011 15.3 0.5 1.5 1 0 0 1 1 1 1 Leucine-rich repeat 2-Hacid_dh_C PF02826.19 RLN26433.1 - 1.5e-44 151.5 0.0 2.3e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 RLN26433.1 - 3.5e-05 24.0 0.0 6.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 RLN26433.1 - 0.0047 17.5 0.1 0.016 15.8 0.0 1.9 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 RLN26433.1 - 0.034 13.7 0.0 0.098 12.2 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Rossmann-like PF10727.9 RLN26433.1 - 0.05 13.5 0.1 0.2 11.5 0.1 1.9 1 1 1 2 2 2 0 Rossmann-like domain Sacchrp_dh_NADP PF03435.18 RLN26433.1 - 0.06 13.6 0.0 0.32 11.3 0.0 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 RLN26433.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 RLN26433.1 - 0.2 11.3 0.1 0.41 10.3 0.1 1.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 RLN26433.1 - 0.22 11.5 0.1 0.8 9.7 0.1 2.0 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Alpha_kinase PF02816.18 RLN26434.1 - 5.1e-30 105.0 0.0 7.9e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.6 RLN26434.1 - 1.1e-06 29.2 0.0 2.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 RLN26434.1 - 1e-05 25.9 0.0 1.7e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain DZR PF12773.7 RLN26434.1 - 2.3 8.3 11.8 22 5.2 10.4 2.8 1 1 0 1 1 1 0 Double zinc ribbon Na_H_Exchanger PF00999.21 RLN26435.1 - 7.6e-56 189.5 32.6 9.1e-56 189.3 32.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family EGF_2 PF07974.13 RLN26446.1 - 2.1e-16 59.9 66.9 0.00041 20.7 3.2 7.9 7 0 0 7 7 7 7 EGF-like domain DUF3072 PF11272.8 RLN26446.1 - 0.041 13.8 1.6 0.098 12.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) EGF PF00008.27 RLN26446.1 - 0.19 12.0 56.0 0.038 14.3 9.8 7.3 7 0 0 7 7 7 0 EGF-like domain PseudoU_synth_2 PF00849.22 RLN26447.1 - 6.6e-26 91.3 0.0 1.2e-25 90.5 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase CAP_N PF01213.19 RLN26447.1 - 0.48 9.9 3.7 0.98 8.8 3.7 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Kinesin PF00225.23 RLN26448.1 - 2.8e-79 266.5 0.1 1.7e-78 263.9 0.1 2.1 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN26448.1 - 3.1e-13 49.9 1.5 1.3e-12 47.9 0.2 2.6 2 1 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 RLN26448.1 - 0.0015 18.9 0.0 0.0015 18.9 0.0 3.0 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 RLN26448.1 - 0.0021 18.3 0.3 0.047 14.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain PIF1 PF05970.14 RLN26448.1 - 0.007 15.6 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_7 PF12775.7 RLN26448.1 - 0.0082 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region ssDBP PF17878.1 RLN26448.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 Single-stranded DNA-binding protein DUF87 PF01935.17 RLN26448.1 - 0.019 15.1 0.1 0.069 13.2 0.0 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain Sigma54_activat PF00158.26 RLN26448.1 - 0.043 13.5 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 RLN26448.1 - 0.055 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 RLN26448.1 - 0.058 13.8 0.0 0.18 12.2 0.0 1.8 2 0 0 2 2 2 0 RNA helicase DUF2075 PF09848.9 RLN26448.1 - 0.063 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 RLN26448.1 - 0.072 13.0 0.0 0.7 9.8 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 RLN26448.1 - 0.095 13.0 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 RLN26448.1 - 0.17 11.7 0.5 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein Pox_A_type_inc PF04508.12 RLN26448.1 - 0.67 9.9 7.2 0.21 11.5 1.9 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat NOA36 PF06524.12 RLN26448.1 - 5.2 6.3 4.9 8.7 5.6 4.9 1.3 1 0 0 1 1 1 0 NOA36 protein EHD_N PF16880.5 RLN26449.1 - 1.2e-17 63.5 1.6 1.5e-17 63.1 1.6 1.1 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Caskin1-CID PF16600.5 RLN26449.1 - 0.19 12.4 3.0 0.13 12.9 1.6 1.5 2 0 0 2 2 2 0 Caskin1 CASK-interaction domain Piwi PF02171.17 RLN26450.1 - 3.9e-83 279.2 0.0 4.9e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 RLN26450.1 - 1.1e-15 58.5 0.0 1.8e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 RLN26450.1 - 6.6e-12 45.4 0.0 1.2e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 RLN26450.1 - 6.7e-11 42.3 0.1 1.7e-10 41.0 0.1 1.6 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL1 PF08699.10 RLN26450.1 - 1.6e-10 40.5 0.0 3.3e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 RLN26450.1 - 2e-08 34.4 0.0 4.8e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain DUF1515 PF07439.11 RLN26452.1 - 0.19 11.8 1.4 6.6 6.8 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) NPV_P10 PF05531.12 RLN26452.1 - 1.9 9.0 6.2 1.7 9.1 0.9 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 RLN26452.1 - 2.3 8.3 13.7 0.99 9.4 2.7 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 RLN26452.1 - 3.7 7.0 15.9 12 5.3 16.0 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit FliJ PF02050.16 RLN26452.1 - 4.2 7.6 23.1 0.36 11.1 11.1 3.5 4 0 0 4 4 4 0 Flagellar FliJ protein V_ATPase_I PF01496.19 RLN26452.1 - 4.5 5.1 10.7 1.3 6.9 5.3 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family SlyX PF04102.12 RLN26452.1 - 6 7.6 16.1 0.71 10.5 7.7 3.4 2 1 0 2 2 2 0 SlyX Crystall_3 PF08964.10 RLN26453.1 - 0.11 12.7 0.5 20 5.4 0.1 3.3 3 0 0 3 3 3 0 Beta/Gamma crystallin DEAD PF00270.29 RLN26454.1 - 8.4e-17 61.5 0.0 1.9e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HRDC PF00570.23 RLN26454.1 - 1.1e-14 54.2 0.0 2.7e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Helicase_C PF00271.31 RLN26454.1 - 6.1e-09 36.2 0.0 2.1e-08 34.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-GRF PF06839.12 RLN26454.1 - 0.00021 21.3 1.0 0.00021 21.3 1.0 2.0 2 0 0 2 2 2 1 GRF zinc finger Ogr_Delta PF04606.12 RLN26454.1 - 0.58 10.2 2.4 3.1 7.9 2.4 2.3 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger Enkurin PF13864.6 RLN26454.1 - 2 8.9 5.5 5.5 7.5 0.1 3.2 2 1 1 3 3 3 0 Calmodulin-binding Pantoate_ligase PF02569.15 RLN26455.1 - 7.4e-100 333.6 0.0 8.7e-100 333.3 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase fn3 PF00041.21 RLN26461.1 - 1.6e-05 25.1 0.1 0.24 11.8 0.0 3.0 2 0 0 2 2 2 2 Fibronectin type III domain POTRA_1 PF08478.10 RLN26461.1 - 0.048 14.0 0.1 23 5.4 0.0 4.3 4 0 0 4 4 4 0 POTRA domain, FtsQ-type BLOC1_2 PF10046.9 RLN26466.1 - 0.48 10.8 7.0 0.38 11.1 0.7 3.0 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 RLN26466.1 - 0.98 9.9 4.7 1.4 9.4 0.6 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 RLN26466.1 - 2.1 7.8 8.1 2.9 7.4 8.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit USP8_interact PF08941.10 RLN26466.1 - 7.6 6.3 7.6 6.3 6.6 0.3 2.1 2 0 0 2 2 2 0 USP8 interacting Secretin_N PF03958.17 RLN26467.1 - 0.046 14.1 0.7 0.51 10.8 0.1 2.5 2 1 0 2 2 2 0 Bacterial type II/III secretion system short domain AvrLm4-7 PF18661.1 RLN26467.1 - 4.3 8.4 6.4 20 6.3 0.5 3.0 2 2 1 3 3 3 0 Avirulence Effector AvrLm4-7 NAD_kinase PF01513.21 RLN26468.1 - 3.7e-62 210.1 0.0 6.2e-62 209.4 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 RLN26468.1 - 0.0035 17.0 0.0 0.0071 16.0 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DMAP_binding PF06464.11 RLN26468.1 - 0.05 14.4 0.0 0.099 13.5 0.0 1.5 1 0 0 1 1 1 0 DMAP1-binding Domain UreD PF01774.17 RLN26469.1 - 1.3e-48 165.7 0.1 1.7e-48 165.4 0.1 1.1 1 0 0 1 1 1 1 UreD urease accessory protein DUF5329 PF17263.2 RLN26469.1 - 0.14 12.3 0.0 0.51 10.5 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5329) Methyltr_RsmB-F PF01189.17 RLN26470.1 - 0.0016 18.1 0.1 0.0016 18.1 0.1 2.2 2 1 0 2 2 2 1 16S rRNA methyltransferase RsmB/F CCSAP PF15748.5 RLN26470.1 - 0.14 12.3 20.0 0.17 12.0 20.0 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DDHD PF02862.17 RLN26470.1 - 0.47 10.6 11.1 0.57 10.3 11.1 1.1 1 0 0 1 1 1 0 DDHD domain Spt20 PF12090.8 RLN26470.1 - 0.82 9.2 14.8 1.3 8.6 14.8 1.4 1 0 0 1 1 1 0 Spt20 family VIR_N PF15912.5 RLN26470.1 - 1.7 8.2 11.0 1.9 8.0 11.0 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal CRT10 PF08728.10 RLN26470.1 - 1.7 6.7 5.3 1.8 6.6 5.3 1.0 1 0 0 1 1 1 0 CRT10 MCM_bind PF09739.9 RLN26470.1 - 1.8 6.9 11.5 1.9 6.8 11.5 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor RR_TM4-6 PF06459.12 RLN26470.1 - 2 8.2 21.5 2.6 7.8 21.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIF_alpha PF05793.12 RLN26470.1 - 2.4 6.6 29.1 2.8 6.4 29.1 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAM60A PF15396.6 RLN26470.1 - 2.8 7.9 13.2 3.1 7.7 13.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A V_ATPase_I PF01496.19 RLN26470.1 - 3.8 5.3 11.3 4.2 5.1 11.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.8 RLN26470.1 - 4.8 5.9 9.2 5.3 5.7 9.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2201_N PF13203.6 RLN26470.1 - 5.2 6.6 13.5 7.1 6.1 13.5 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain SAPS PF04499.15 RLN26470.1 - 8 5.1 13.5 8.6 5.0 13.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DNA_pol_B PF00136.21 RLN26471.1 - 4.5e-21 75.1 0.0 5.6e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 RLN26471.1 - 0.0011 19.4 8.8 0.0023 18.3 8.8 1.4 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta FYVE PF01363.21 RLN26471.1 - 1.2 9.4 10.0 0.062 13.4 3.5 2.1 1 1 1 2 2 2 0 FYVE zinc finger DNA_pol_B PF00136.21 RLN26472.1 - 1.2e-58 199.0 0.0 1.4e-58 198.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 RLN26472.1 - 5.2e-08 32.4 0.0 1.1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain ABC_tran PF00005.27 RLN26473.1 - 1e-70 236.5 0.0 2.4e-35 122.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 RLN26473.1 - 2.7e-48 165.0 15.7 3.5e-48 164.6 15.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 RLN26473.1 - 1.8e-12 47.2 3.9 2.5e-05 23.8 0.0 4.1 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RLN26473.1 - 3.3e-09 37.4 1.0 0.0034 17.8 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 RLN26473.1 - 1.2e-08 34.5 0.5 0.0034 17.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 RLN26473.1 - 3.6e-08 33.6 0.6 0.49 10.2 0.1 4.1 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 RLN26473.1 - 5.9e-08 33.1 1.2 0.021 15.1 0.0 3.8 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN26473.1 - 6.1e-08 32.2 0.0 0.007 15.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_15 PF13175.6 RLN26473.1 - 4.1e-07 30.0 0.0 0.0084 15.9 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 RLN26473.1 - 2.3e-06 26.7 0.4 0.059 12.2 0.1 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA PF00004.29 RLN26473.1 - 3.3e-06 27.5 1.3 0.049 14.1 0.1 3.9 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 RLN26473.1 - 3.6e-06 27.0 0.0 0.12 12.2 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase APS_kinase PF01583.20 RLN26473.1 - 1e-05 25.5 0.1 0.11 12.4 0.0 2.4 2 0 0 2 2 2 2 Adenylylsulphate kinase DUF87 PF01935.17 RLN26473.1 - 3.9e-05 23.9 0.3 0.081 13.0 0.0 2.7 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_30 PF13604.6 RLN26473.1 - 4.8e-05 23.2 0.8 0.36 10.5 0.3 3.0 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.14 RLN26473.1 - 5.6e-05 23.2 0.9 0.37 10.8 0.0 3.9 4 1 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 RLN26473.1 - 8.3e-05 22.3 0.2 0.99 8.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 RLN26473.1 - 0.00011 22.7 0.0 0.44 11.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 RLN26473.1 - 0.00017 21.7 0.0 0.67 10.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 RLN26473.1 - 0.00021 21.4 3.6 2.4 8.4 0.3 4.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 RLN26473.1 - 0.00025 21.3 0.0 0.9 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain G-alpha PF00503.20 RLN26473.1 - 0.00029 20.1 0.0 0.7 9.0 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_24 PF13479.6 RLN26473.1 - 0.0006 19.6 0.1 1.4 8.6 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 RLN26473.1 - 0.00072 19.1 0.0 0.7 9.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 RLN26473.1 - 0.0041 17.2 0.2 6.1 7.0 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase TetR_C_14 PF17754.1 RLN26473.1 - 0.005 16.8 0.0 9.3 6.2 0.0 3.3 3 0 0 3 3 3 0 MftR C-terminal domain DUF815 PF05673.13 RLN26473.1 - 0.0065 15.7 0.0 0.49 9.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NTPase_1 PF03266.15 RLN26473.1 - 0.01 15.7 1.0 15 5.5 0.0 4.0 4 0 0 4 4 4 0 NTPase ATP_bind_1 PF03029.17 RLN26473.1 - 0.012 15.4 0.2 4 7.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 RLN26473.1 - 0.015 15.8 0.3 2 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 RLN26473.1 - 0.017 14.9 1.8 4.5 7.0 0.2 3.6 2 2 0 2 2 2 0 DEAD/DEAH box helicase IstB_IS21 PF01695.17 RLN26473.1 - 0.03 14.0 0.1 7.6 6.2 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 RLN26473.1 - 0.031 13.6 0.0 2.7 7.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family SRP54 PF00448.22 RLN26473.1 - 0.036 13.7 0.0 7.3 6.2 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Ploopntkinase1 PF18748.1 RLN26473.1 - 0.05 13.1 0.1 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 NACHT PF05729.12 RLN26473.1 - 0.05 13.5 2.1 11 6.0 0.0 3.3 4 0 0 4 4 3 0 NACHT domain AAA_17 PF13207.6 RLN26473.1 - 0.061 13.7 0.0 22 5.5 0.0 3.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 RLN26473.1 - 0.072 12.5 0.0 3.1 7.1 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 RLN26473.1 - 0.074 13.0 0.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain Ploopntkinase3 PF18751.1 RLN26473.1 - 0.084 12.8 0.0 23 4.8 0.0 2.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 RLN26473.1 - 0.086 13.2 0.0 12 6.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 RLN26473.1 - 0.16 11.2 0.1 5.4 6.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain MtrB PF05440.12 RLN26473.1 - 0.18 12.2 3.6 1.1e+02 3.4 1.0 5.0 5 0 0 5 5 5 0 Tetrahydromethanopterin S-methyltransferase subunit B PKD_channel PF08016.12 RLN26475.1 - 8.3e-35 120.3 3.1 1.2e-34 119.8 3.1 1.1 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 RLN26475.1 - 0.15 11.2 4.1 0.32 10.2 4.1 1.5 1 0 0 1 1 1 0 Ion transport protein PPR_long PF17177.4 RLN26476.1 - 1.6e-34 119.2 0.6 5.9e-34 117.3 0.1 1.9 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PRORP PF16953.5 RLN26476.1 - 7.7e-34 117.3 0.0 2.3e-31 109.2 0.0 2.2 2 0 0 2 2 2 2 Protein-only RNase P PPR_3 PF13812.6 RLN26476.1 - 2e-06 27.8 0.0 6.7e-05 22.9 0.0 1.7 1 1 1 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 RLN26476.1 - 0.0014 18.7 0.0 0.09 13.1 0.0 2.7 2 0 0 2 2 2 1 PPR repeat RNase_Zc3h12a PF11977.8 RLN26476.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain PPR_2 PF13041.6 RLN26476.1 - 0.19 11.9 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 PPR repeat family Pkinase PF00069.25 RLN26478.1 - 1.8e-55 188.2 0.0 2.5e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN26478.1 - 3.8e-28 98.5 0.0 1.3e-27 96.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN26478.1 - 4.2e-07 29.6 0.0 1.3e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN26478.1 - 0.0013 18.1 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN26478.1 - 0.15 12.0 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_S10 PF00450.22 RLN26479.1 - 1.4e-67 228.9 1.6 1.7e-67 228.7 1.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Ribosomal_S2 PF00318.20 RLN26483.1 - 2.7e-28 98.7 0.1 4.4e-15 55.5 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 RLN26483.1 - 0.00071 20.9 19.8 0.0012 20.1 19.8 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus PWWP PF00855.17 RLN26484.1 - 3.5e-09 37.0 2.1 3.5e-09 37.0 2.1 4.6 5 1 0 5 5 5 1 PWWP domain Apelin PF15360.6 RLN26484.1 - 0.08 13.5 1.1 0.48 11.0 1.1 2.4 1 0 0 1 1 1 0 APJ endogenous ligand Cofilin_ADF PF00241.20 RLN26485.1 - 1.8e-10 40.7 0.0 2.2e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cofilin_ADF PF00241.20 RLN26486.1 - 3.5e-14 52.6 0.0 5.4e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SRP19 PF01922.17 RLN26487.1 - 1.8e-30 105.7 0.0 3.4e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 SRP19 protein fn3 PF00041.21 RLN26488.1 - 4.7e-46 155.1 29.7 1.6e-13 50.8 0.1 10.3 10 1 0 10 10 10 9 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RLN26488.1 - 2.4e-14 53.6 15.1 1.5e-05 25.5 0.1 8.4 8 0 0 8 8 8 4 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 RLN26488.1 - 2.3e-09 37.5 3.8 0.072 13.5 0.0 5.9 7 0 0 7 7 7 3 Uncharacterised conserved protein (DUF2369) NAR2 PF16974.5 RLN26488.1 - 0.0034 16.8 4.7 7.2 6.0 0.0 4.7 6 0 0 6 6 6 2 High-affinity nitrate transporter accessory DHO_dh PF01180.21 RLN26489.1 - 1.7e-103 345.9 0.0 2e-103 345.7 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 RLN26489.1 - 0.026 13.9 0.2 0.057 12.8 0.2 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase DUF2958 PF11171.8 RLN26489.1 - 0.1 12.9 0.1 8.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2958) Hist_deacetyl PF00850.19 RLN26490.1 - 1.1e-65 222.2 0.3 1.2e-65 222.0 0.3 1.0 1 0 0 1 1 1 1 Histone deacetylase domain FliJ PF02050.16 RLN26491.1 - 0.017 15.4 1.1 0.017 15.4 1.1 2.5 2 1 1 3 3 3 0 Flagellar FliJ protein TetR_C_13 PF16925.5 RLN26491.1 - 0.59 10.1 3.4 0.52 10.3 1.0 2.0 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain MAP65_ASE1 PF03999.12 RLN26491.1 - 0.78 8.4 6.7 2.4 6.8 0.5 2.0 1 1 1 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) UCH PF00443.29 RLN26492.1 - 4.5e-30 105.0 0.1 7.4e-30 104.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN26492.1 - 9.2e-20 71.5 0.0 2.4e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 RLN26492.1 - 2.2e-12 46.6 0.0 4.1e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUSP PF06337.12 RLN26492.1 - 1.9e-06 28.4 0.0 0.47 11.1 0.0 3.6 3 0 0 3 3 3 2 DUSP domain zf-RanBP PF00641.18 RLN26492.1 - 5.6e-05 22.4 12.2 0.00012 21.3 1.1 3.5 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others Rad60-SLD PF11976.8 RLN26492.1 - 0.025 14.4 0.0 0.07 13.0 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like zf-FPG_IleRS PF06827.14 RLN26492.1 - 0.036 13.9 0.6 0.16 11.8 0.0 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS AAA_2 PF07724.14 RLN26508.1 - 6.2e-51 172.9 0.0 2.3e-47 161.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 RLN26508.1 - 5.2e-34 116.3 3.2 5.2e-34 116.3 3.2 2.9 1 1 1 2 2 1 1 AAA lid domain ClpB_D2-small PF10431.9 RLN26508.1 - 6.4e-25 87.0 0.0 2.1e-24 85.3 0.0 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 RLN26508.1 - 1.8e-22 80.2 0.6 1.2e-13 51.7 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RLN26508.1 - 2.5e-17 63.2 0.6 7.9e-12 45.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RLN26508.1 - 5.6e-09 36.6 4.5 0.00051 20.5 0.1 4.8 4 1 1 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.26 RLN26508.1 - 4.5e-07 29.7 0.0 0.0019 17.9 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 RLN26508.1 - 6.5e-07 28.9 0.2 0.046 13.1 0.1 3.5 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 RLN26508.1 - 1.2e-06 28.9 5.1 0.0061 16.8 0.0 4.7 2 2 3 5 5 4 2 AAA domain IstB_IS21 PF01695.17 RLN26508.1 - 2e-05 24.4 0.0 0.057 13.2 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.6 RLN26508.1 - 3.2e-05 23.6 2.5 0.00066 19.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain TniB PF05621.11 RLN26508.1 - 5.9e-05 22.5 0.6 0.066 12.6 0.0 4.3 4 1 0 4 4 4 1 Bacterial TniB protein AAA_7 PF12775.7 RLN26508.1 - 0.00023 20.7 0.0 0.35 10.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region RuvB_N PF05496.12 RLN26508.1 - 0.00031 20.5 3.9 1.9 8.2 0.0 4.0 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 RLN26508.1 - 0.00033 21.0 0.0 1.7 9.0 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_24 PF13479.6 RLN26508.1 - 0.00044 20.0 0.0 0.55 9.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 RLN26508.1 - 0.00049 20.6 7.2 0.43 11.1 0.0 3.9 3 2 1 4 4 3 2 AAA domain NACHT PF05729.12 RLN26508.1 - 0.00081 19.3 0.0 0.065 13.1 0.0 2.8 3 0 0 3 3 2 1 NACHT domain AAA_23 PF13476.6 RLN26508.1 - 0.00089 19.8 9.9 4.8 7.6 10.6 3.4 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 RLN26508.1 - 0.00091 19.2 0.0 1.3 9.0 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase TsaE PF02367.17 RLN26508.1 - 0.0012 18.8 0.5 1.9 8.5 0.0 2.9 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 RLN26508.1 - 0.0014 18.9 0.1 1.7 8.9 0.0 2.7 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase TIP49 PF06068.13 RLN26508.1 - 0.002 17.4 0.1 0.94 8.6 0.0 2.6 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 RLN26508.1 - 0.003 17.7 0.0 4.8 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 RLN26508.1 - 0.011 16.1 0.9 1.7 8.9 0.7 3.5 3 1 0 3 3 3 0 AAA domain AAA_28 PF13521.6 RLN26508.1 - 0.019 15.2 2.3 11 6.2 0.0 3.8 3 1 1 4 4 4 0 AAA domain PduV-EutP PF10662.9 RLN26508.1 - 0.024 14.4 0.0 0.74 9.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_3 PF07726.11 RLN26508.1 - 0.024 14.5 0.1 15 5.4 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 RLN26508.1 - 0.028 14.3 9.4 2.9 7.8 0.2 4.7 4 2 0 4 4 3 0 ATPase domain predominantly from Archaea DNA_pol3_delta2 PF13177.6 RLN26508.1 - 0.032 14.0 0.0 14 5.4 0.0 3.5 3 0 0 3 3 3 0 DNA polymerase III, delta subunit ABC_tran PF00005.27 RLN26508.1 - 0.043 14.3 1.9 6.7 7.2 0.0 3.6 3 1 0 3 3 3 0 ABC transporter Torsin PF06309.11 RLN26508.1 - 0.11 12.5 0.0 0.46 10.6 0.0 1.9 2 0 0 2 2 1 0 Torsin ATP_bind_1 PF03029.17 RLN26508.1 - 0.13 12.1 0.0 2.9 7.6 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 RLN26508.1 - 0.19 11.3 2.5 4.4 6.9 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain GAS PF13851.6 RLN26508.1 - 0.31 10.3 12.5 0.8 9.0 12.5 1.7 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 RLN26508.1 - 1.4 8.2 6.9 2.9 7.2 6.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 RLN26508.1 - 1.7 6.5 6.8 2.2 6.1 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 RLN26508.1 - 3.4 6.7 5.5 5.9 5.9 5.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF848 PF05852.11 RLN26508.1 - 4.5 7.4 10.2 3 8.0 6.7 2.3 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) OrfB_Zn_ribbon PF07282.11 RLN26509.1 - 8.4e-09 35.2 1.0 2.5e-08 33.7 1.0 1.8 1 1 0 1 1 1 1 Putative transposase DNA-binding domain GTP_EFTU_D3 PF03143.17 RLN26528.1 - 3.5e-42 143.2 0.0 6.5e-42 142.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 RLN26528.1 - 5e-13 49.2 0.1 9.9e-13 48.3 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 RLN26528.1 - 0.071 13.0 1.1 0.15 12.0 0.2 1.9 2 0 0 2 2 2 0 Elongation factor Tu domain 4 DUF89 PF01937.19 RLN26529.1 - 0.00054 19.0 0.0 0.00067 18.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 Sugar_tr PF00083.24 RLN26530.1 - 9.9e-98 327.9 19.8 1.2e-97 327.6 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN26530.1 - 1.2e-23 83.6 31.9 1.2e-23 83.6 31.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily NEMP PF10225.9 RLN26530.1 - 0.093 12.4 0.2 0.093 12.4 0.2 2.2 2 0 0 2 2 2 0 NEMP family DUF2583 PF10762.9 RLN26530.1 - 0.45 11.0 4.6 1.7 9.2 4.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) UreF PF01730.16 RLN26553.1 - 6.3e-26 91.5 8.4 9.1e-26 91.0 8.4 1.2 1 0 0 1 1 1 1 UreF PBP3 PF18056.1 RLN26553.1 - 0.0044 17.1 0.0 0.11 12.6 0.0 2.1 1 1 1 2 2 2 1 Penicillin Binding Protein 3 Domain Dimer_Tnp_hAT PF05699.14 RLN26561.1 - 0.0061 16.3 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4777 PF16007.5 RLN26561.1 - 0.044 14.0 0.2 0.16 12.3 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) ABC_tran PF00005.27 RLN26562.1 - 1.9e-53 180.7 0.0 2.2e-29 102.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 RLN26562.1 - 1.2e-33 116.7 46.5 1e-18 67.6 11.2 3.8 4 0 0 4 4 4 2 ABC-2 family transporter protein AAA_21 PF13304.6 RLN26562.1 - 1.6e-16 61.0 0.8 2.4e-05 24.3 0.0 4.1 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 RLN26562.1 - 8.5e-06 25.9 0.0 0.72 10.1 0.0 4.8 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 RLN26562.1 - 0.00054 20.5 0.8 0.015 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain MukB PF04310.12 RLN26562.1 - 0.0012 18.7 3.3 0.69 9.7 0.3 2.9 3 0 0 3 3 3 2 MukB N-terminal SMC_N PF02463.19 RLN26562.1 - 0.0024 17.3 4.0 1.3 8.4 0.0 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RLN26562.1 - 0.0027 17.4 3.0 0.07 12.9 0.4 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 RLN26562.1 - 0.0048 16.7 0.0 0.98 9.1 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_16 PF13191.6 RLN26562.1 - 0.015 15.7 0.1 8.2 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 RLN26562.1 - 0.034 13.9 0.1 4.9 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 RLN26562.1 - 0.039 13.2 0.0 16 4.7 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin RsgA_GTPase PF03193.16 RLN26562.1 - 0.084 12.8 0.4 0.85 9.5 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase DUF87 PF01935.17 RLN26562.1 - 0.15 12.2 0.8 5.4 7.0 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Mg_chelatase PF01078.21 RLN26562.1 - 0.17 11.3 0.1 0.79 9.1 0.0 2.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI SRP54 PF00448.22 RLN26562.1 - 0.25 11.0 3.1 7.3 6.2 0.4 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Pkinase_Tyr PF07714.17 RLN26564.1 - 1.8e-15 56.9 0.0 2.8e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN26564.1 - 2e-10 40.5 0.0 3.2e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN26565.1 - 1.2e-14 54.3 0.0 2.1e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN26565.1 - 1.4e-09 37.8 0.0 2.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF2597 PF10772.9 RLN26566.1 - 0.023 14.7 0.8 1.6 8.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2597) betaPIX_CC PF16523.5 RLN26566.1 - 0.41 10.5 2.6 0.95 9.3 0.3 2.3 2 1 0 2 2 2 0 betaPIX coiled coil DUF1400 PF07176.11 RLN26567.1 - 0.0015 18.9 0.1 0.004 17.4 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1400) DUF648 PF04890.13 RLN26567.1 - 0.061 13.1 0.4 0.097 12.4 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF648) FlxA PF14282.6 RLN26569.1 - 0.25 11.4 7.4 0.46 10.5 7.4 1.4 1 0 0 1 1 1 0 FlxA-like protein TFIIA PF03153.13 RLN26571.1 - 1.1 9.2 46.6 0.032 14.3 12.2 2.5 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TPR_19 PF14559.6 RLN26580.1 - 5.1e-09 36.5 3.5 2.6e-07 31.0 0.2 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN26580.1 - 5.2e-07 29.9 2.6 0.74 10.8 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN26580.1 - 1.7e-06 27.7 0.3 0.44 10.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN26580.1 - 1e-05 25.1 0.1 0.098 12.5 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN26580.1 - 0.0004 20.6 0.7 0.1 13.0 0.0 4.0 4 1 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN26580.1 - 0.00087 19.5 2.7 0.035 14.3 0.1 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 RLN26580.1 - 0.0048 16.8 0.0 2.6 8.3 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN26580.1 - 0.016 15.4 2.9 0.018 15.2 1.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN26580.1 - 3.3 8.4 11.0 4.4 8.0 0.8 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ParcG PF10274.9 RLN26581.1 - 3.5e-68 229.3 0.0 4.7e-34 118.1 0.0 2.1 2 0 0 2 2 2 2 Parkin co-regulated protein Ldt_C PF17969.1 RLN26582.1 - 1.5 9.6 4.2 2.5 8.9 0.2 3.2 2 0 0 2 2 2 0 L,D-transpeptidase C-terminal domain APG6_N PF17675.1 RLN26583.1 - 0.41 11.2 15.0 0.66 10.5 2.0 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF2205 PF10224.9 RLN26583.1 - 3 7.9 10.1 8.8 6.4 0.0 3.2 3 0 0 3 3 3 0 Short coiled-coil protein DUF1664 PF07889.12 RLN26583.1 - 3.2 7.8 6.9 1.4 9.0 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CLZ PF16526.5 RLN26583.1 - 6.4 7.2 9.8 4.3 7.8 0.2 3.2 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels THOC7 PF05615.13 RLN26583.1 - 6.8 7.0 12.8 0.53 10.6 1.1 2.4 2 0 0 2 2 2 0 Tho complex subunit 7 Ank_4 PF13637.6 RLN26584.1 - 1.4e-09 38.3 0.6 1.1e-05 25.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN26584.1 - 1.4e-07 32.0 0.0 3.3e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN26584.1 - 2.5e-07 30.8 0.2 5.4e-07 29.8 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 RLN26584.1 - 7e-06 26.3 0.9 0.0014 19.0 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 RLN26584.1 - 5.2e-05 23.3 0.9 0.0041 17.5 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat BBS2_N PF14781.6 RLN26585.1 - 0.086 12.7 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal TPR_1 PF00515.28 RLN26586.1 - 3e-10 39.4 2.9 0.00011 21.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN26586.1 - 1.2e-07 31.3 6.4 0.0013 18.7 0.7 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN26586.1 - 3.1e-05 24.1 2.1 0.091 13.2 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN26586.1 - 0.0035 17.4 0.8 0.21 11.9 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN26586.1 - 0.0045 17.5 4.6 0.035 14.6 0.2 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN26586.1 - 0.0062 16.7 2.4 0.0062 16.7 2.4 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN26586.1 - 0.046 14.0 1.5 0.18 12.1 1.5 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 RLN26586.1 - 0.049 13.9 5.6 0.039 14.3 2.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN26586.1 - 0.094 13.4 4.9 3.5 8.4 0.1 4.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 RLN26586.1 - 0.1 12.3 0.7 0.47 10.2 0.3 2.5 2 0 0 2 2 2 0 TPR repeat TPR_7 PF13176.6 RLN26586.1 - 0.13 12.3 6.0 5.3 7.3 0.2 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN26586.1 - 1.9 8.5 4.4 1.2 9.1 0.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF501 PF04417.12 RLN26588.1 - 4.9e-38 130.1 0.1 6.5e-38 129.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF501) DUF726 PF05277.12 RLN26589.1 - 2.2e-14 53.2 0.0 2.5e-09 36.5 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF726) DUF676 PF05057.14 RLN26589.1 - 0.046 13.2 0.0 0.29 10.6 0.0 1.9 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 RLN26589.1 - 0.082 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.7 RLN26589.1 - 1.7 9.2 14.1 0.024 15.2 1.8 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family LRR_6 PF13516.6 RLN26590.1 - 2.5e-16 58.3 19.4 0.0011 18.9 0.0 9.2 11 0 0 11 11 11 5 Leucine Rich repeat LRR_4 PF12799.7 RLN26590.1 - 1.1e-11 44.8 7.5 0.032 14.6 0.0 6.8 5 3 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN26590.1 - 0.00037 20.7 10.0 49 5.0 0.0 8.0 9 1 0 9 9 9 0 Leucine Rich Repeat LRR_8 PF13855.6 RLN26590.1 - 0.017 14.9 8.5 3.5 7.4 0.1 5.3 5 3 0 5 5 5 0 Leucine rich repeat PLDc_3 PF13918.6 RLN26608.1 - 5.5e-06 26.1 0.0 8.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain PLDc_2 PF13091.6 RLN26608.1 - 0.00041 20.3 0.0 0.0011 18.8 0.0 1.7 1 1 0 1 1 1 1 PLD-like domain PLDc PF00614.22 RLN26608.1 - 0.00071 19.7 0.1 0.0013 18.8 0.1 1.5 1 0 0 1 1 1 1 Phospholipase D Active site motif Anoctamin PF04547.12 RLN26609.1 - 2.1e-121 405.9 14.7 2.6e-121 405.6 14.7 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF2207 PF09972.9 RLN26609.1 - 0.06 12.1 2.0 0.24 10.1 0.1 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2427 PF10348.9 RLN26609.1 - 5.7 6.8 8.6 2.3 8.0 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) NOG1 PF06858.14 RLN26611.1 - 4.5e-27 93.6 0.9 9.7e-27 92.5 0.2 2.1 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 RLN26611.1 - 5.1e-24 84.0 1.2 1.1e-23 82.9 1.2 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 RLN26611.1 - 1.3e-17 63.9 0.0 3.7e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOG1_N PF17835.1 RLN26611.1 - 1.2e-10 41.6 0.0 1.2e-10 41.6 0.0 2.9 3 0 0 3 3 3 1 NOG1 N-terminal helical domain FeoB_N PF02421.18 RLN26611.1 - 2e-10 40.4 0.1 3.4e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 RLN26611.1 - 0.00014 21.5 0.3 0.0003 20.4 0.3 1.6 1 1 0 1 1 1 1 Ras family Dynamin_N PF00350.23 RLN26611.1 - 0.079 13.0 5.2 4.6 7.3 0.0 3.5 3 1 1 4 4 4 0 Dynamin family Roc PF08477.13 RLN26611.1 - 0.091 13.0 0.0 1.5 9.1 0.0 2.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 RLN26611.1 - 0.1 13.0 0.0 0.1 13.0 0.0 2.7 2 2 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.9 RLN26611.1 - 0.13 12.0 0.2 0.3 10.8 0.2 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NDC10_II PF16787.5 RLN26612.1 - 1.2e-29 103.4 0.0 1.1e-14 54.2 0.0 2.1 1 1 1 2 2 2 2 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 RLN26612.1 - 3.1e-18 65.8 0.0 5.8e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Zn_peptidase_2 PF04298.12 RLN26642.1 - 0.18 11.2 0.0 0.23 10.9 0.0 1.1 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Pkinase PF00069.25 RLN26643.1 - 3.9e-30 105.1 0.0 2.7e-20 72.8 0.0 3.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN26643.1 - 2.1e-16 60.0 0.0 1.6e-09 37.4 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN26643.1 - 0.00021 20.2 0.0 0.0024 16.7 0.0 2.1 1 1 1 2 2 2 1 Fungal protein kinase APH PF01636.23 RLN26643.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-RING_5 PF14634.6 RLN26643.1 - 0.43 10.6 15.7 0.78 9.8 15.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_6 PF14835.6 RLN26643.1 - 3.3 7.7 7.9 2.6 8.0 3.5 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein PHD PF00628.29 RLN26644.1 - 4.3e-06 26.5 5.3 4.3e-06 26.5 5.3 3.4 3 1 0 3 3 3 2 PHD-finger MBT PF02820.18 RLN26644.1 - 0.1 13.0 0.6 0.21 12.0 0.1 1.8 2 0 0 2 2 2 0 mbt repeat Methyltr_RsmB-F PF01189.17 RLN26646.1 - 1.7e-33 116.0 0.0 8e-31 107.2 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F DHFR_1 PF00186.19 RLN26646.1 - 9.1e-32 110.0 0.0 1.6e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 Dihydrofolate reductase zf-CCHC_2 PF13696.6 RLN26646.1 - 2e-05 24.3 0.2 4.7e-05 23.1 0.2 1.6 1 0 0 1 1 1 1 Zinc knuckle FtsJ PF01728.19 RLN26646.1 - 0.00066 19.8 0.0 0.003 17.7 0.0 2.0 3 0 0 3 3 3 1 FtsJ-like methyltransferase PAP2 PF01569.21 RLN26647.1 - 0.041 13.6 6.1 0.024 14.4 3.8 1.7 2 0 0 2 2 2 0 PAP2 superfamily DUF4131 PF13567.6 RLN26647.1 - 1.1 8.9 4.0 14 5.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DSPc PF00782.20 RLN26648.1 - 1.7e-17 63.5 0.1 2.6e-17 62.9 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DSPn PF14671.6 RLN26648.1 - 0.0082 16.6 0.8 0.022 15.2 0.8 1.7 1 1 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half CH_2 PF06294.11 RLN26649.1 - 0.045 13.9 0.0 0.099 12.8 0.0 1.6 1 0 0 1 1 1 0 CH-like domain in sperm protein Ribosomal_S18 PF01084.20 RLN26649.1 - 0.14 12.3 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S18 Cu-oxidase_2 PF07731.14 RLN26650.1 - 2.3e-37 127.8 3.3 8.3e-28 96.8 0.1 4.2 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN26650.1 - 5.3e-34 116.8 2.6 3e-32 111.1 0.1 3.3 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 RLN26650.1 - 8.3e-26 91.0 0.0 4.2e-25 88.7 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 RLN26651.1 - 3e-38 130.7 2.9 9.8e-30 103.1 0.2 4.1 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN26651.1 - 1.3e-32 112.3 2.0 1.2e-29 102.7 0.2 4.1 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 RLN26651.1 - 7.4e-26 91.2 0.1 3e-25 89.2 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase DUF3881 PF12997.7 RLN26651.1 - 0.21 10.8 0.0 0.37 10.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) Symplekin_C PF12295.8 RLN26677.1 - 5e-42 144.1 6.9 6.1e-42 143.8 4.9 2.1 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal VHL_C PF17211.3 RLN26677.1 - 0.072 13.1 0.5 0.43 10.6 0.2 2.4 2 0 0 2 2 2 0 VHL box domain Anophelin PF10731.9 RLN26677.1 - 0.42 10.5 1.9 0.92 9.4 1.9 1.5 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito Aminotran_1_2 PF00155.21 RLN26678.1 - 1.7e-51 175.5 0.0 2e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 RLN26678.1 - 2e-05 24.1 0.2 2.8e-05 23.6 0.2 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 RLN26678.1 - 0.0013 18.2 0.3 0.0033 16.8 0.3 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 RLN26678.1 - 0.0013 17.7 0.1 0.0022 17.0 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 RLN26678.1 - 0.0014 17.3 0.0 0.0021 16.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 RLN26678.1 - 0.0035 16.1 0.3 0.0084 14.9 0.3 1.7 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain LRR_4 PF12799.7 RLN26681.1 - 0.025 15.0 0.1 26 5.4 0.0 3.5 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RLN26681.1 - 0.18 12.0 0.9 1.5e+02 2.8 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat AAA_16 PF13191.6 RLN26683.1 - 3.1e-13 50.5 1.3 1.2e-11 45.3 1.3 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RLN26683.1 - 4.2e-05 23.9 2.9 0.025 14.8 0.0 3.3 4 0 0 4 4 4 2 AAA domain DAP3 PF10236.9 RLN26683.1 - 0.0029 16.9 0.8 0.0072 15.5 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 RLN26683.1 - 0.0052 16.7 4.7 0.025 14.5 0.0 3.5 4 1 0 4 4 4 1 NACHT domain AAA_19 PF13245.6 RLN26683.1 - 0.065 13.6 0.0 0.3 11.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 RLN26683.1 - 0.095 12.9 0.6 2.7 8.2 0.0 2.9 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ATPase PF06745.13 RLN26683.1 - 0.15 11.4 0.0 6.1 6.1 0.0 3.0 3 0 0 3 3 3 0 KaiC AAA PF00004.29 RLN26683.1 - 0.74 10.2 2.4 8.7 6.8 0.0 3.3 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Guanylate_cyc PF00211.20 RLN26684.1 - 2e-08 34.1 0.0 4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ARL2_Bind_BART PF11527.8 RLN26685.1 - 3.3e-20 72.3 1.1 1.2e-19 70.5 0.0 2.6 3 0 0 3 3 3 1 The ARF-like 2 binding protein BART WW PF00397.26 RLN26685.1 - 1.6e-06 28.0 3.2 3.7e-06 26.9 3.2 1.6 1 0 0 1 1 1 1 WW domain DUF726 PF05277.12 RLN26686.1 - 8e-94 314.4 2.4 1.1e-71 241.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF726) KTI12 PF08433.10 RLN26688.1 - 7.9e-75 251.8 0.0 8.9e-75 251.6 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 RLN26688.1 - 9.1e-13 48.6 0.4 1.8e-12 47.6 0.1 1.6 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 RLN26688.1 - 2.5e-06 27.5 0.0 4.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.29 RLN26688.1 - 3.1e-05 24.4 0.1 0.00052 20.4 0.0 2.4 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RLN26688.1 - 0.00013 22.6 0.0 0.00042 20.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 RLN26688.1 - 0.0018 18.0 0.1 0.36 10.5 0.1 2.4 1 1 0 1 1 1 1 Thymidylate kinase AAA_5 PF07728.14 RLN26688.1 - 0.0024 17.9 0.2 0.18 11.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) 6PF2K PF01591.18 RLN26688.1 - 0.0043 16.4 0.3 0.16 11.3 0.3 2.2 1 1 0 1 1 1 1 6-phosphofructo-2-kinase SKI PF01202.22 RLN26688.1 - 0.0051 16.9 0.0 0.0093 16.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Zeta_toxin PF06414.12 RLN26688.1 - 0.0053 16.1 0.1 0.026 13.8 0.1 2.1 1 1 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 RLN26688.1 - 0.0057 17.0 0.8 0.029 14.8 0.8 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RLN26688.1 - 0.0098 16.2 0.1 0.023 14.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 RLN26688.1 - 0.023 14.1 0.1 0.051 13.0 0.1 1.5 1 1 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 RLN26688.1 - 0.026 13.7 0.1 0.12 11.6 0.1 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 RLN26688.1 - 0.042 14.2 0.0 0.07 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.15 RLN26688.1 - 0.046 13.7 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 RLN26688.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 RLN26688.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 RLN26688.1 - 0.34 11.1 2.2 0.79 9.9 0.7 2.3 2 1 0 2 2 2 0 AAA domain Frag1 PF10277.9 RLN26689.1 - 9.8e-11 41.6 13.9 3.3e-10 39.9 13.9 1.8 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family HemY_N PF07219.13 RLN26689.1 - 0.076 13.2 1.7 0.24 11.6 0.5 2.3 1 1 1 2 2 2 0 HemY protein N-terminus SPX PF03105.19 RLN26689.1 - 0.89 9.4 13.8 1.2 9.0 13.8 1.1 1 0 0 1 1 1 0 SPX domain bZIP_2 PF07716.15 RLN26693.1 - 0.11 12.6 17.3 0.032 14.3 6.6 2.4 2 0 0 2 2 2 0 Basic region leucine zipper TMEM192 PF14802.6 RLN26693.1 - 0.23 10.5 1.0 0.36 9.9 1.0 1.3 1 0 0 1 1 1 0 TMEM192 family bZIP_1 PF00170.21 RLN26693.1 - 1.6 8.8 17.5 0.21 11.7 10.0 2.3 1 1 1 2 2 2 0 bZIP transcription factor zf-CCCH PF00642.24 RLN26694.1 - 7.7e-19 67.1 37.7 1.4e-05 24.9 1.9 5.4 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RLN26694.1 - 1.8e-18 65.9 42.1 1.4e-05 24.9 4.0 4.9 4 0 0 4 4 4 4 Zinc finger domain zf-CCCH_4 PF18044.1 RLN26694.1 - 6.2e-18 64.2 38.6 1.4e-07 31.2 2.1 5.8 6 0 0 6 6 6 4 CCCH-type zinc finger Torus PF16131.5 RLN26694.1 - 1.9e-15 57.5 20.0 0.00082 20.1 0.1 4.5 2 1 2 4 4 4 4 Torus domain zf-RING_2 PF13639.6 RLN26694.1 - 5.5e-08 33.0 7.1 9.2e-08 32.3 4.4 2.9 2 0 0 2 2 2 1 Ring finger domain zf-CCCH_2 PF14608.6 RLN26694.1 - 6e-08 32.9 40.3 0.015 15.8 3.2 5.4 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 RLN26694.1 - 3.6e-07 30.4 18.7 0.04 14.1 1.0 4.5 3 1 1 4 4 4 4 Zinc-finger containing family zf-C3HC4 PF00097.25 RLN26694.1 - 1.2e-06 28.3 3.6 1.2e-06 28.3 3.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN26694.1 - 5.8e-06 26.1 5.8 7.1e-05 22.6 3.2 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN26694.1 - 3.5e-05 23.7 4.1 3.5e-05 23.7 4.1 2.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RLN26694.1 - 0.00043 20.3 3.1 0.0013 18.7 3.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 RLN26694.1 - 0.0049 16.7 2.9 0.0049 16.7 2.9 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 RLN26694.1 - 0.054 13.8 8.0 0.31 11.4 8.0 2.4 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 RLN26694.1 - 0.24 11.3 9.3 0.61 10.0 7.1 3.0 2 1 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN26694.1 - 0.25 11.1 6.1 0.22 11.3 2.2 2.9 2 0 0 2 2 2 0 RING-like zinc finger FANCL_C PF11793.8 RLN26694.1 - 0.3 11.3 7.3 0.073 13.3 3.3 2.2 2 0 0 2 2 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 RLN26694.1 - 0.69 10.1 7.5 0.078 13.1 2.3 2.3 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 RLN26694.1 - 8.5 6.5 10.9 0.27 11.3 3.0 2.7 3 1 0 3 3 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger A_deamin PF02137.18 RLN26695.1 - 5.3e-61 206.9 0.9 5.3e-57 193.7 0.2 2.1 1 1 0 2 2 2 2 Adenosine-deaminase (editase) domain TMEM65 PF10507.9 RLN26695.1 - 2.6e-39 133.5 5.0 4.9e-30 103.7 0.6 2.9 1 1 1 2 2 2 2 Transmembrane protein 65 Rib_5-P_isom_A PF06026.14 RLN26696.1 - 3.5e-62 209.1 0.0 1.1e-61 207.5 0.0 1.7 2 0 0 2 2 2 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind PF04198.13 RLN26696.1 - 0.0075 15.4 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Putative sugar-binding domain DeoRC PF00455.22 RLN26696.1 - 0.026 14.4 0.0 0.11 12.5 0.0 1.8 2 1 0 2 2 2 0 DeoR C terminal sensor domain TetR_C_16 PF17920.1 RLN26697.1 - 0.09 13.0 0.9 49 4.2 0.0 4.0 4 1 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain DUF1488 PF07369.11 RLN26697.1 - 0.22 11.5 1.3 0.84 9.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1488) Sigma70_ner PF04546.13 RLN26697.1 - 0.5 10.2 4.5 0.38 10.6 0.5 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region CH_2 PF06294.11 RLN26698.1 - 9.2e-09 35.3 0.0 2.2e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 CH-like domain in sperm protein AA_permease_N PF08403.10 RLN26698.1 - 0.089 12.3 0.0 0.41 10.2 0.0 2.0 2 0 0 2 2 2 0 Amino acid permease N-terminal Pectate_lyase PF03211.13 RLN26699.1 - 1.4e-37 129.2 5.5 3.3e-37 128.0 5.5 1.6 1 0 0 1 1 1 1 Pectate lyase NTP_transf_2 PF01909.23 RLN26700.1 - 0.021 15.1 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain RRM_1 PF00076.22 RLN26705.1 - 3.6e-12 45.9 0.0 5.1e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 RLN26705.1 - 0.14 12.2 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 RNA binding domain TPR_16 PF13432.6 RLN26706.1 - 0.0079 16.8 0.6 0.074 13.7 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN26706.1 - 0.017 15.4 3.3 5.6 7.3 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN26706.1 - 0.029 14.9 3.1 0.095 13.2 0.1 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat YfdX PF10938.8 RLN26706.1 - 0.032 14.2 2.1 0.17 11.8 1.3 2.3 1 1 0 1 1 1 0 YfdX protein ANAPC3 PF12895.7 RLN26706.1 - 0.079 13.2 3.6 0.65 10.3 0.0 2.6 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 RLN26706.1 - 0.2 11.9 4.9 17 5.8 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 RLN26706.1 - 0.95 9.9 4.7 15 6.1 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN26706.1 - 2.8 9.0 5.8 3.1 8.9 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat CarboxypepD_reg PF13620.6 RLN26707.1 - 5e-06 26.7 0.0 0.0048 17.1 0.0 2.9 2 0 0 2 2 2 2 Carboxypeptidase regulatory-like domain MatE PF01554.18 RLN26708.1 - 1.8e-56 190.2 18.0 2.1e-29 102.2 8.2 3.1 3 1 0 4 4 4 2 MatE MurJ PF03023.14 RLN26708.1 - 4.9e-07 28.7 14.0 7.9e-07 28.0 14.0 1.3 1 0 0 1 1 1 1 Lipid II flippase MurJ Polysacc_synt_C PF14667.6 RLN26708.1 - 3.5 7.7 36.9 6.6 6.8 2.9 4.5 2 1 2 4 4 4 0 Polysaccharide biosynthesis C-terminal domain Pkinase PF00069.25 RLN26716.1 - 3.2e-56 190.6 0.0 4.3e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN26716.1 - 1.1e-26 93.7 0.0 1.4e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN26716.1 - 7.9e-09 35.2 0.0 1.3e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN26716.1 - 0.00033 20.7 0.1 0.00067 19.6 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN26716.1 - 0.0026 16.6 0.0 0.004 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PH PF00169.29 RLN26716.1 - 0.0044 17.5 0.0 0.009 16.5 0.0 1.4 1 0 0 1 1 1 1 PH domain Pkinase_C PF00433.24 RLN26716.1 - 0.018 15.7 0.2 0.046 14.4 0.2 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain Seadorna_VP7 PF07387.11 RLN26716.1 - 0.032 13.3 0.1 0.052 12.6 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 RLN26716.1 - 0.18 10.7 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain NADH-u_ox-rdase PF10785.9 RLN26717.1 - 3.6e-22 78.8 0.1 4.9e-22 78.4 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit MINDY_DUB PF04424.13 RLN26718.1 - 1.1e-24 86.7 0.0 2.4e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 MINDY deubiquitinase SnoaL_2 PF12680.7 RLN26720.1 - 0.0034 18.0 0.0 0.0053 17.4 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain Ribosomal_S17e PF00833.18 RLN26726.1 - 2.4e-58 195.4 0.6 2.6e-58 195.3 0.6 1.0 1 0 0 1 1 1 1 Ribosomal S17 tRNA_anti-codon PF01336.25 RLN26727.1 - 0.12 12.3 0.0 0.23 11.5 0.0 1.7 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain CSRNP_N PF16019.5 RLN26728.1 - 0.007 16.3 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus Myb_DNA-binding PF00249.31 RLN26729.1 - 7.2e-11 42.1 0.4 1.4e-10 41.2 0.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN26729.1 - 0.0012 18.7 0.6 0.0026 17.6 0.6 1.4 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 RLN26729.1 - 0.0076 16.5 0.2 0.014 15.6 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Snf7 PF03357.21 RLN26730.1 - 5.8e-39 133.4 15.0 5.8e-39 133.4 15.0 2.0 1 1 1 2 2 2 1 Snf7 Phage_TAC_5 PF08890.11 RLN26730.1 - 0.0079 16.2 0.5 0.013 15.5 0.5 1.3 1 0 0 1 1 1 1 Phage XkdN-like tail assembly chaperone protein, TAC CCDC24 PF15669.5 RLN26730.1 - 0.02 14.8 0.8 0.02 14.8 0.8 2.4 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 24 family DUF3138 PF11336.8 RLN26730.1 - 0.053 12.1 5.8 0.027 13.1 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) zf-C3H2C3 PF17122.5 RLN26731.1 - 0.079 13.0 0.3 0.15 12.1 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger EF-hand_7 PF13499.6 RLN26732.1 - 1.4e-11 44.6 0.5 1.9e-11 44.2 0.5 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN26732.1 - 3.5e-11 41.8 0.3 1.1e-07 30.9 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN26732.1 - 1.4e-08 33.9 0.3 4.8e-07 29.2 0.1 2.4 2 1 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 RLN26732.1 - 3.2e-07 30.1 0.8 0.0022 17.8 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN26732.1 - 0.00058 19.2 0.5 0.0094 15.4 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 RLN26732.1 - 0.0019 18.5 0.1 0.0042 17.4 0.1 1.5 1 1 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 RLN26732.1 - 0.026 14.5 0.2 0.1 12.5 0.1 1.8 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF4601 PF15373.6 RLN26732.1 - 0.12 11.3 0.1 0.15 11.0 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) ORC3_N PF07034.11 RLN26733.1 - 3.4e-14 52.7 9.8 4.3e-13 49.1 4.3 3.4 3 1 0 3 3 3 2 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 RLN26733.1 - 3.1e-09 37.1 2.3 7.1e-08 32.6 0.5 3.3 2 1 0 2 2 2 1 Origin recognition complex winged helix C-terminal RFC1 PF08519.12 RLN26733.1 - 0.25 11.5 1.4 1.2 9.3 0.1 2.8 2 1 0 2 2 2 0 Replication factor RFC1 C terminal domain RNA_pol_N PF01194.17 RLN26734.1 - 1.1e-30 105.7 1.2 2e-30 104.9 1.2 1.4 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 RLN26734.1 - 0.05 13.9 0.6 0.05 13.9 0.6 1.7 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) PI3K_1B_p101 PF10486.9 RLN26735.1 - 1.3 6.7 11.9 2.5 5.8 11.9 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PALP PF00291.25 RLN26736.1 - 1.3e-64 218.5 0.0 1.5e-64 218.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1891 PF09004.10 RLN26737.1 - 0.4 10.3 2.7 0.65 9.6 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) Pkinase PF00069.25 RLN26738.1 - 1.4e-59 201.6 0.0 2.1e-59 201.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN26738.1 - 3.6e-27 95.3 0.0 6.1e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 RLN26738.1 - 1.4e-05 25.6 1.0 0.006 17.1 0.9 2.4 2 0 0 2 2 2 1 PH domain APH PF01636.23 RLN26738.1 - 0.00038 20.5 0.1 0.00038 20.5 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN26738.1 - 0.0023 17.3 0.1 0.0044 16.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TetR_C_6 PF13977.6 RLN26738.1 - 0.014 15.6 1.0 0.038 14.2 1.0 1.7 1 0 0 1 1 1 0 BetI-type transcriptional repressor, C-terminal Haspin_kinase PF12330.8 RLN26738.1 - 0.02 13.9 0.1 0.033 13.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 RLN26738.1 - 0.039 12.7 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SnoaL_2 PF12680.7 RLN26738.1 - 0.04 14.6 0.1 0.17 12.5 0.1 2.2 1 1 0 1 1 1 0 SnoaL-like domain PH_9 PF15410.6 RLN26738.1 - 0.054 13.9 0.2 3.3 8.1 0.1 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Choline_kinase PF01633.20 RLN26738.1 - 0.09 12.4 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MAGI_u5 PF16666.5 RLN26738.1 - 0.13 12.4 4.5 0.14 12.3 0.7 2.8 2 0 0 2 2 2 0 Unstructured region on MAGI Ribosomal_S9 PF00380.19 RLN26739.1 - 1.2e-48 164.6 0.1 2.1e-48 163.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 WD40 PF00400.32 RLN26740.1 - 5.3e-18 65.0 20.9 0.00051 20.8 0.2 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat PEN-2 PF10251.9 RLN26740.1 - 5.9e-13 49.1 4.4 4.7e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 Presenilin enhancer-2 subunit of gamma secretase ANAPC4_WD40 PF12894.7 RLN26740.1 - 2.1e-07 31.1 1.1 0.095 13.0 0.4 3.6 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_C48 PF02902.19 RLN26764.1 - 6e-12 45.9 0.2 9.7e-12 45.2 0.2 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Oxidored_FMN PF00724.20 RLN26765.1 - 2.5e-62 211.1 0.0 3.7e-62 210.6 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 RLN26765.1 - 9.3e-27 94.0 2.5 1.4e-26 93.5 2.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RLN26765.1 - 5.9e-10 39.6 5.5 6.5e-05 23.4 0.7 3.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RLN26765.1 - 6.5e-10 39.1 0.5 3.5e-09 36.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 RLN26765.1 - 1.3e-08 34.4 1.1 0.00043 19.6 0.1 2.8 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RLN26765.1 - 4.7e-07 28.9 1.9 1.4e-06 27.3 0.3 2.3 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 RLN26765.1 - 7.9e-06 25.2 0.7 2e-05 23.9 0.7 1.7 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 RLN26765.1 - 1.3e-05 25.1 1.6 0.0016 18.4 0.1 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 RLN26765.1 - 2.4e-05 23.9 0.1 3.5e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 RLN26765.1 - 9.2e-05 22.2 8.9 0.00023 20.9 0.8 4.1 4 1 0 5 5 5 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 RLN26765.1 - 0.00015 21.1 0.6 0.023 14.0 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain FMO-like PF00743.19 RLN26765.1 - 0.0002 19.9 0.1 0.024 13.1 0.0 3.0 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like 2-Hacid_dh_C PF02826.19 RLN26765.1 - 0.00026 20.4 0.1 0.66 9.3 0.1 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 RLN26765.1 - 0.0021 17.7 0.0 0.068 12.7 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 RLN26765.1 - 0.0035 17.3 0.3 0.46 10.4 0.0 2.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.22 RLN26765.1 - 0.0052 15.9 0.9 0.0052 15.9 0.9 2.1 3 1 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 RLN26765.1 - 0.0063 15.8 1.2 0.013 14.8 0.2 2.0 1 1 1 2 2 2 1 Thi4 family ThiF PF00899.21 RLN26765.1 - 0.012 15.0 0.1 0.65 9.3 0.1 2.3 2 0 0 2 2 2 0 ThiF family NAD_binding_9 PF13454.6 RLN26765.1 - 0.026 14.5 7.1 0.098 12.6 0.1 3.5 4 0 0 4 4 4 0 FAD-NAD(P)-binding Bac_luciferase PF00296.20 RLN26765.1 - 0.085 12.3 0.1 5.2 6.4 0.0 2.7 3 0 0 3 3 3 0 Luciferase-like monooxygenase Lycopene_cycl PF05834.12 RLN26765.1 - 0.14 11.1 0.1 0.14 11.1 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein F420_oxidored PF03807.17 RLN26765.1 - 0.16 12.6 0.7 33 5.2 0.1 2.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 RLN26765.1 - 0.23 11.1 3.4 33 4.1 0.0 3.3 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 RLN26765.1 - 0.29 11.6 2.9 1.7 9.2 0.1 2.7 3 0 0 3 3 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 RLN26765.1 - 0.37 10.1 7.0 0.04 13.2 0.5 2.5 3 1 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain PHD PF00628.29 RLN26766.1 - 0.031 14.1 0.5 0.031 14.1 0.5 2.5 3 0 0 3 3 3 0 PHD-finger zf-LYAR PF08790.11 RLN26767.1 - 7.4e-15 54.5 6.0 3.9e-14 52.2 2.7 2.4 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger C1_4 PF07975.12 RLN26767.1 - 0.22 11.8 4.4 0.73 10.1 4.4 1.9 1 0 0 1 1 1 0 TFIIH C1-like domain Arg_decarbox_C PF17944.1 RLN26767.1 - 0.29 11.7 2.6 0.5 11.0 1.9 1.8 1 1 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension VPS11_C PF12451.8 RLN26767.1 - 0.34 11.2 1.7 0.89 9.8 1.7 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal zinc_ribbon_12 PF11331.8 RLN26767.1 - 0.49 10.2 2.6 1.5 8.7 2.6 1.8 1 0 0 1 1 1 0 Probable zinc-ribbon domain Thioredoxin PF00085.20 RLN26768.1 - 4.8e-21 74.7 0.4 9.2e-21 73.8 0.4 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 RLN26768.1 - 0.00049 20.5 0.5 0.0032 17.9 0.1 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RLN26768.1 - 0.0058 16.9 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 RLN26768.1 - 0.0081 16.1 0.1 0.014 15.3 0.1 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 RLN26768.1 - 0.016 15.0 0.8 0.047 13.5 0.0 2.1 2 1 1 3 3 3 0 Thioredoxin OST3_OST6 PF04756.13 RLN26768.1 - 0.045 13.1 0.1 0.059 12.7 0.1 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Hid1 PF12722.7 RLN26768.1 - 4.7 5.2 10.2 5.4 5.0 10.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PX PF00787.24 RLN26769.1 - 1.2e-13 51.1 0.1 1.7e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 PX domain Glyco_hydro_30 PF02055.16 RLN26770.1 - 1.5e-24 86.6 0.6 1.9e-24 86.3 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30 PF02055.16 RLN26771.1 - 2.2e-106 355.7 2.4 2.9e-106 355.4 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 RLN26771.1 - 1.2e-12 47.8 5.0 2.5e-12 46.8 5.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Alpha-L-AF_C PF06964.12 RLN26771.1 - 0.037 14.1 0.5 0.078 13.1 0.5 1.5 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase C-terminal domain DUF1966 PF09260.11 RLN26771.1 - 0.039 14.2 1.1 0.063 13.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1966) AAA_25 PF13481.6 RLN26792.1 - 0.046 13.3 0.1 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Y_phosphatase PF00102.27 RLN26792.1 - 0.053 13.1 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase SATase_N PF06426.14 RLN26792.1 - 0.12 12.8 0.1 0.49 10.8 0.1 2.0 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal HTH_32 PF13565.6 RLN26795.1 - 0.011 16.3 1.3 0.039 14.6 0.2 2.4 2 1 1 3 3 3 0 Homeodomain-like domain MULE PF10551.9 RLN26795.1 - 0.021 15.2 0.1 0.13 12.7 0.1 2.3 2 0 0 2 2 2 0 MULE transposase domain DUF3920 PF13058.6 RLN26795.1 - 0.19 12.0 0.1 0.45 10.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) Trp_oprn_chp PF09534.10 RLN26797.1 - 0.19 11.5 1.6 0.45 10.3 1.6 1.6 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CN_hydrolase PF00795.22 RLN26798.1 - 3.9e-33 114.9 0.0 5.4e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 RLN26798.1 - 1.3e-24 86.6 0.2 5.7e-24 84.5 0.2 1.8 1 1 0 1 1 1 1 NAD synthase UCH PF00443.29 RLN26799.1 - 2.8e-23 82.8 0.7 5.7e-23 81.7 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN26799.1 - 2.5e-08 33.9 8.1 5.2e-07 29.6 8.1 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pkinase_C PF00433.24 RLN26800.1 - 2.4e-05 24.9 0.3 4.3e-05 24.1 0.3 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Cation_ATPase_C PF00689.21 RLN26801.1 - 7.1e-45 152.9 4.6 7.3e-43 146.4 1.0 2.7 2 0 0 2 2 2 2 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 RLN26801.1 - 2.7e-37 128.0 0.1 2.7e-37 128.0 0.1 3.3 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 RLN26801.1 - 9.3e-20 71.8 0.2 2.4e-19 70.5 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN26801.1 - 2.3e-16 59.6 0.0 5.5e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 RLN26801.1 - 1.7e-06 27.6 1.3 6.1e-06 25.8 0.0 2.6 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RLN26801.1 - 0.00027 20.8 0.3 0.02 14.6 0.3 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1218 PF06749.12 RLN26801.1 - 0.15 12.6 6.3 1.1 9.8 0.2 4.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1218) DUF4231 PF14015.6 RLN26801.1 - 0.18 12.3 4.9 12 6.5 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) HAD PF12710.7 RLN26801.1 - 0.18 12.2 0.0 0.4 11.1 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 RLN26801.1 - 2.4 7.0 12.4 0.21 10.5 0.1 3.5 4 0 0 4 4 4 0 Major Facilitator Superfamily HlyIII PF03006.20 RLN26801.1 - 3 7.5 12.7 0.029 14.1 0.8 3.0 4 0 0 4 4 4 0 Haemolysin-III related Bax1-I PF01027.20 RLN26801.1 - 6.9 6.4 17.2 0.13 12.0 0.5 3.7 4 0 0 4 4 4 0 Inhibitor of apoptosis-promoting Bax1 DUF1104 PF06518.11 RLN26802.1 - 1 9.7 6.1 0.56 10.6 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1104) APG6_N PF17675.1 RLN26802.1 - 1.4 9.5 19.1 0.47 11.0 3.7 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region CSRNP_N PF16019.5 RLN26802.1 - 5.1 7.0 12.8 0.1 12.5 2.6 2.1 1 1 1 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Not3 PF04065.15 RLN26806.1 - 5.1e-85 284.6 21.9 6.7e-85 284.2 21.9 1.1 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 RLN26806.1 - 6.6e-43 145.9 8.3 1.7e-42 144.6 8.3 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF1664 PF07889.12 RLN26806.1 - 0.16 12.0 8.0 0.11 12.5 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 RLN26806.1 - 6.9 7.4 8.6 0.64 10.7 0.5 2.5 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) zf-C3HC4 PF00097.25 RLN26811.1 - 3.4e-09 36.4 8.3 8e-09 35.2 8.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FHA PF00498.26 RLN26811.1 - 5.1e-09 36.4 0.0 9.2e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-C3HC4_2 PF13923.6 RLN26811.1 - 1.9e-08 34.0 8.7 4.1e-08 32.9 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN26811.1 - 5.5e-08 33.0 9.6 5.5e-08 33.0 9.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 RLN26811.1 - 1e-07 32.0 11.6 2.3e-07 30.9 11.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 RLN26811.1 - 2.2e-07 30.6 4.9 5.7e-07 29.3 4.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN26811.1 - 2.8e-07 30.5 8.5 5.8e-07 29.4 8.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN26811.1 - 0.00027 20.8 7.4 0.00068 19.5 7.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RLN26811.1 - 0.0014 18.4 7.2 0.0039 17.0 7.2 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 RLN26811.1 - 0.0019 18.5 9.6 0.0073 16.6 9.6 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 RLN26811.1 - 0.011 15.6 2.7 0.027 14.3 2.7 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF4451 PF14616.6 RLN26811.1 - 0.015 15.5 1.1 0.35 11.1 1.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) zf-ANAPC11 PF12861.7 RLN26811.1 - 0.11 12.5 2.0 0.34 11.0 2.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 RLN26811.1 - 0.2 11.8 3.1 0.48 10.6 3.1 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 RLN26811.1 - 1.2 9.0 6.6 3.7 7.4 6.6 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 RLN26811.1 - 1.6 8.6 7.3 5.9 6.8 7.5 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain TTL PF03133.15 RLN26812.1 - 4.9e-66 222.8 0.6 1e-65 221.8 0.6 1.4 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RLN26812.1 - 2e-05 24.0 0.1 0.00087 18.6 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RLN26812.1 - 0.00069 19.0 0.3 0.0013 18.1 0.1 1.5 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp CCDC50_N PF15295.6 RLN26813.1 - 0.29 11.3 7.8 5 7.3 0.3 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus CcdA PF07362.12 RLN26813.1 - 0.34 11.4 0.1 0.34 11.4 0.1 2.1 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA Spt5_N PF11942.8 RLN26813.1 - 1.1 10.2 11.7 0.55 11.2 5.3 2.7 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal PQQ_3 PF13570.6 RLN26814.1 - 0.15 12.6 0.3 3.6 8.2 0.1 2.9 3 0 0 3 3 3 0 PQQ-like domain CENP-B_N PF04218.13 RLN26815.1 - 9.7e-05 21.9 0.1 0.0002 20.9 0.1 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 RLN26815.1 - 0.00066 19.8 0.1 0.0011 19.0 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain BrkDBD PF09607.10 RLN26815.1 - 0.00077 19.2 0.0 0.0021 17.8 0.0 1.7 1 0 0 1 1 1 1 Brinker DNA-binding domain HTH_Tnp_1 PF01527.20 RLN26815.1 - 0.0063 16.8 0.1 0.016 15.5 0.1 1.6 1 0 0 1 1 1 1 Transposase R3H PF01424.22 RLN26816.1 - 1.9e-14 53.4 0.1 3.1e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 R3H domain SUZ PF12752.7 RLN26816.1 - 1.5e-10 41.6 1.7 1.5e-10 41.6 1.7 4.4 4 1 0 4 4 4 1 SUZ domain CAP_N PF01213.19 RLN26816.1 - 0.5 9.8 2.3 1.3 8.4 2.3 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal WD40 PF00400.32 RLN26818.1 - 4.4e-12 46.3 14.5 0.011 16.5 0.0 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat LysM PF01476.20 RLN26818.1 - 2.9e-07 30.4 0.0 6.6e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 LysM domain TPR_12 PF13424.6 RLN26818.1 - 0.0012 19.1 1.9 0.021 15.1 1.4 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 RLN26818.1 - 0.044 14.1 0.5 21 5.5 0.0 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain zf-C2HC_2 PF13913.6 RLN26818.1 - 0.08 12.9 0.7 0.21 11.5 0.7 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Sec7 PF01369.20 RLN26819.1 - 3.5e-59 199.6 0.6 7.4e-59 198.5 0.6 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 RLN26819.1 - 1.2e-09 38.3 1.4 1.2e-09 38.3 1.4 2.2 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal PH PF00169.29 RLN26819.1 - 7.7e-06 26.4 0.0 2.1e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 PH domain OrfB_Zn_ribbon PF07282.11 RLN26819.1 - 4.3e-05 23.3 2.8 0.11 12.5 0.3 3.0 3 0 0 3 3 3 2 Putative transposase DNA-binding domain TetR_C_20 PF17925.1 RLN26819.1 - 0.072 13.4 0.6 11 6.4 0.3 3.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain BING4CT PF08149.11 RLN26820.1 - 7.7e-39 131.4 0.0 2.2e-35 120.3 0.0 3.0 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 RLN26820.1 - 1e-07 32.1 0.0 1.7 9.0 0.0 4.6 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RLN26820.1 - 1.7e-06 28.6 0.0 0.047 14.6 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Y2_Tnp PF04986.13 RLN26820.1 - 0.026 14.6 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative transposase HflK_N PF12221.8 RLN26820.1 - 0.18 11.9 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial membrane protein N terminal Spo7 PF03907.13 RLN26821.1 - 0.93 8.9 4.6 2 7.8 4.6 1.5 1 0 0 1 1 1 0 Spo7-like protein SET PF00856.28 RLN26937.1 - 8.6e-10 39.2 1.1 1.2e-08 35.6 1.1 2.0 1 1 0 1 1 1 1 SET domain AWS PF17907.1 RLN26937.1 - 0.018 15.1 0.3 0.018 15.1 0.3 1.9 2 0 0 2 2 2 0 AWS domain Ank_4 PF13637.6 RLN26938.1 - 5.7e-14 52.3 15.2 8.9e-07 29.4 0.2 4.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN26938.1 - 1.5e-11 44.7 7.6 3.2e-05 24.4 0.6 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN26938.1 - 1.2e-10 41.5 8.8 0.017 15.5 0.2 6.3 1 1 5 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN26938.1 - 1.1e-05 25.4 0.9 3.1 8.6 0.0 6.0 6 2 1 7 7 7 1 Ankyrin repeat Rhomboid PF01694.22 RLN26938.1 - 0.003 17.6 0.3 0.0053 16.8 0.3 1.3 1 0 0 1 1 1 1 Rhomboid family His_Phos_1 PF00300.22 RLN26939.1 - 2e-09 37.4 1.0 0.00021 21.1 0.1 3.8 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 1) REPA_OB_2 PF16900.5 RLN26940.1 - 2.8e-12 46.4 0.0 8.4e-10 38.5 0.0 2.3 2 0 0 2 2 2 2 Replication protein A OB domain DUF223 PF02721.14 RLN26940.1 - 0.025 14.9 0.0 0.051 13.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF223 tRNA_anti-codon PF01336.25 RLN26940.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain CwfJ_C_1 PF04677.15 RLN26942.1 - 2.6e-30 104.8 0.4 5.6e-30 103.7 0.4 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 RLN26942.1 - 8.5e-27 93.9 0.0 3.3e-26 92.0 0.0 2.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Baculo_11_kDa PF06143.11 RLN26943.1 - 0.14 11.8 3.5 0.53 9.9 0.1 2.1 2 0 0 2 2 2 0 Baculovirus 11 kDa family BCDHK_Adom3 PF10436.9 RLN26946.1 - 3.2e-53 179.9 0.0 4.5e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 RLN26946.1 - 1.8e-13 51.0 0.0 3.9e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 RLN26946.1 - 0.00019 21.3 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fmp27_WPPW PF10359.9 RLN26947.1 - 0.0077 15.1 1.6 0.0077 15.1 1.6 3.0 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain DEDD_Tnp_IS110 PF01548.17 RLN26947.1 - 0.067 13.1 1.2 0.26 11.2 1.2 2.0 1 0 0 1 1 1 0 Transposase DUF4815 PF16075.5 RLN26947.1 - 0.078 11.3 0.1 0.14 10.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4815) TMPIT PF07851.13 RLN26947.1 - 0.14 11.3 11.6 0.052 12.8 0.3 3.3 4 0 0 4 4 4 0 TMPIT-like protein NPV_P10 PF05531.12 RLN26947.1 - 0.24 11.9 13.2 5.1 7.6 0.3 5.4 5 1 2 7 7 7 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 RLN26947.1 - 0.35 10.9 9.3 0.86 9.6 0.2 4.4 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fez1 PF06818.15 RLN26947.1 - 0.36 11.3 20.3 0.57 10.6 5.0 3.4 3 0 0 3 3 3 0 Fez1 BEX PF04538.12 RLN26947.1 - 0.58 10.8 3.2 3.1 8.4 3.2 2.3 1 1 0 1 1 1 0 Brain expressed X-linked like family FlxA PF14282.6 RLN26947.1 - 0.82 9.7 5.0 2.6 8.1 0.2 3.8 3 0 0 3 3 3 0 FlxA-like protein Occludin_ELL PF07303.13 RLN26947.1 - 4.1 8.2 14.4 1.2 9.9 1.3 5.0 5 1 1 7 7 7 0 Occludin homology domain N_BRCA1_IG PF16158.5 RLN26948.1 - 3.1e-34 117.7 0.1 1.2e-33 115.9 0.0 2.0 2 0 0 2 2 2 1 Ig-like domain from next to BRCA1 gene PB1 PF00564.24 RLN26948.1 - 7.1e-08 32.3 0.1 3.5e-07 30.1 0.0 2.1 2 1 0 2 2 2 1 PB1 domain B2-adapt-app_C PF09066.10 RLN26949.1 - 6.8e-07 29.4 0.4 2.1e-06 27.8 0.1 1.9 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain zf-rbx1 PF12678.7 RLN26950.1 - 4.5e-08 33.2 0.3 4.5e-08 33.2 0.3 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 RLN26950.1 - 1.9e-06 28.1 0.7 1.9e-06 28.1 0.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN26950.1 - 3.6e-05 23.5 1.0 8.8e-05 22.3 1.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN26950.1 - 4.5e-05 23.1 0.2 9.5e-05 22.1 0.2 1.6 1 0 0 1 1 1 1 RING-like zinc finger PHD PF00628.29 RLN26950.1 - 4.6e-05 23.2 3.7 4.6e-05 23.2 3.7 2.5 2 0 0 2 2 2 1 PHD-finger zf-C3HC4 PF00097.25 RLN26950.1 - 0.00023 21.0 0.2 0.00023 21.0 0.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RLN26950.1 - 0.0019 18.2 0.3 0.0019 18.2 0.3 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD_2 PF13831.6 RLN26950.1 - 0.0024 17.4 1.2 0.0024 17.4 1.2 1.8 2 0 0 2 2 2 1 PHD-finger zf-RING_4 PF14570.6 RLN26950.1 - 0.054 13.3 0.2 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 RLN26950.1 - 0.065 13.1 0.3 0.065 13.1 0.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 RLN26950.1 - 0.12 12.2 0.1 0.12 12.2 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 RLN26950.1 - 0.25 11.7 7.9 2.4 8.5 1.4 2.6 2 0 0 2 2 2 0 RING-like domain zf-C3H2C3 PF17122.5 RLN26950.1 - 0.4 10.7 1.9 1.1 9.3 1.9 1.7 1 0 0 1 1 1 0 Zinc-finger zf-HC5HC2H PF13771.6 RLN26950.1 - 7.8 6.8 9.5 0.6 10.4 0.9 2.7 2 1 0 2 2 2 0 PHD-like zinc-binding domain UPF0231 PF06062.11 RLN26951.1 - 4.4 7.6 7.6 2.4 8.4 1.1 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0231) RabGAP-TBC PF00566.18 RLN26952.1 - 3.3e-32 111.9 0.0 5.5e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TPR_11 PF13414.6 RLN26952.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 TPR repeat TPR_6 PF13174.6 RLN26952.1 - 0.011 16.3 0.2 0.12 13.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN26952.1 - 0.03 15.0 0.1 0.16 12.7 0.1 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN26952.1 - 0.034 15.0 0.1 0.034 15.0 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat YccV-like PF08755.11 RLN26952.1 - 0.056 14.0 0.0 0.23 12.0 0.0 2.0 1 1 0 1 1 1 0 Hemimethylated DNA-binding protein YccV like SH3_2 PF07653.17 RLN26952.1 - 0.078 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain TPR_10 PF13374.6 RLN26952.1 - 0.21 11.5 0.9 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat RPN7 PF10602.9 RLN26953.1 - 1.6e-25 89.8 1.7 3.3e-14 53.0 1.1 4.3 2 2 0 2 2 2 2 26S proteasome subunit RPN7 PCI PF01399.27 RLN26953.1 - 3.4e-15 56.4 0.3 4.6e-14 52.8 0.1 2.5 2 1 0 2 2 2 1 PCI domain TPR_2 PF07719.17 RLN26953.1 - 0.0024 17.9 0.0 0.0091 16.0 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN26953.1 - 0.046 13.6 0.1 0.15 12.0 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN26953.1 - 0.052 13.9 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN26953.1 - 0.17 12.6 2.0 2.2 9.0 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat ALAD PF00490.21 RLN26954.1 - 3.7e-103 345.0 0.0 4.6e-103 344.7 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase ACBP PF00887.19 RLN26955.1 - 8e-14 51.6 0.0 1e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein WHEP-TRS PF00458.20 RLN26956.1 - 2.1e-17 63.0 3.7 2.1e-17 63.0 3.7 2.7 3 0 0 3 3 3 1 WHEP-TRS domain AP1AR PF15745.5 RLN26956.1 - 0.082 12.5 6.2 0.016 14.9 2.2 1.8 1 1 1 2 2 2 0 AP-1 complex-associated regulatory protein SRP-alpha_N PF04086.13 RLN26956.1 - 2.4 8.0 13.4 3 7.7 13.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal zf-HIT PF04438.16 RLN26961.1 - 1.6e-09 37.4 11.4 1.6e-09 37.4 11.4 1.7 2 0 0 2 2 2 1 HIT zinc finger YL1_C PF08265.11 RLN26961.1 - 0.0096 15.7 0.1 0.018 14.8 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Rhamno_transf PF11316.8 RLN26961.1 - 0.17 11.2 6.2 0.44 9.9 0.1 2.4 2 0 0 2 2 2 0 Putative rhamnosyl transferase zf-MYND PF01753.18 RLN26961.1 - 3.8 7.7 18.3 1 9.5 14.2 2.1 2 0 0 2 2 2 0 MYND finger DUF4498 PF14926.6 RLN26962.1 - 2.2e-59 200.8 0.0 2.6e-59 200.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) PH PF00169.29 RLN26963.1 - 1.5e-08 35.0 0.0 1.8e-08 34.8 0.0 1.0 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN26963.1 - 0.037 14.3 0.2 0.13 12.6 0.2 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain Exo_endo_phos PF03372.23 RLN26964.1 - 0.00032 20.3 0.0 0.00093 18.8 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pectinesterase PF01095.19 RLN26964.1 - 0.041 12.6 0.1 0.084 11.6 0.0 1.4 2 0 0 2 2 2 0 Pectinesterase RCC1 PF00415.18 RLN26966.1 - 1.2e-31 109.0 13.8 6.4e-10 39.5 0.6 5.2 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN26966.1 - 2.8e-22 77.9 18.4 9.7e-09 34.8 1.8 4.3 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat EF-hand_7 PF13499.6 RLN26967.1 - 3.1e-22 78.8 0.3 6.3e-12 45.8 0.0 3.3 2 1 0 2 2 2 2 EF-hand domain pair fn3 PF00041.21 RLN26967.1 - 2.9e-21 75.6 0.0 4.4e-06 27.0 0.0 5.3 5 0 0 5 5 5 4 Fibronectin type III domain EF-hand_1 PF00036.32 RLN26967.1 - 1.1e-19 68.5 4.0 6.1e-06 25.4 0.7 4.4 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 RLN26967.1 - 2e-18 65.0 1.1 2e-05 23.8 0.4 4.0 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 RLN26967.1 - 5.3e-15 54.0 7.0 0.00071 19.3 0.1 5.2 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 RLN26967.1 - 1.3e-14 53.7 3.6 0.00016 21.5 0.0 5.4 4 1 1 5 5 5 4 EF-hand domain pair Pur_ac_phosph_N PF16656.5 RLN26967.1 - 2.7e-09 37.5 0.1 0.04 14.5 0.0 5.1 5 0 0 5 5 5 2 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 RLN26967.1 - 7.4e-05 23.1 0.0 0.86 10.0 0.0 4.4 4 0 0 4 4 4 1 Uncharacterised conserved protein (DUF2369) Methyltransf_11 PF08241.12 RLN26968.1 - 1.2e-18 67.5 2.9 3.1e-14 53.4 0.1 3.1 3 1 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 RLN26968.1 - 1.4e-18 67.4 0.6 2.1e-13 50.8 0.1 3.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 RLN26968.1 - 2.8e-15 56.8 0.2 1.1e-08 35.7 0.0 4.4 4 1 0 4 4 4 2 Methyltransferase domain Methyltransf_31 PF13847.6 RLN26968.1 - 9.8e-13 48.2 0.0 3.8e-10 39.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 RLN26968.1 - 2.3e-08 34.0 0.1 0.013 15.4 0.0 2.9 2 1 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 RLN26968.1 - 2.6e-06 27.1 1.0 0.01 15.4 0.0 3.0 3 1 0 3 3 3 2 Methyltransferase small domain Ubie_methyltran PF01209.18 RLN26968.1 - 1.3e-05 24.7 0.1 0.00019 20.9 0.0 2.7 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family Spermine_synth PF01564.17 RLN26968.1 - 0.00011 21.7 0.1 0.0016 17.9 0.1 2.5 2 1 1 3 3 3 1 Spermine/spermidine synthase domain TPMT PF05724.11 RLN26968.1 - 0.012 15.2 0.6 0.12 12.0 0.2 2.6 2 1 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) MetW PF07021.12 RLN26968.1 - 0.13 11.8 0.1 0.45 10.1 0.0 1.8 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW CDK2AP PF09806.9 RLN26968.1 - 0.65 10.0 4.4 1.4 8.9 4.4 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein ANAPC4_WD40 PF12894.7 RLN26970.1 - 5e-08 33.1 0.1 0.028 14.7 0.0 4.2 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RLN26970.1 - 5.7e-07 30.1 4.2 5.2 8.1 0.0 6.0 5 2 1 6 6 6 3 WD domain, G-beta repeat IKI3 PF04762.12 RLN26970.1 - 0.00032 18.9 0.8 0.01 13.9 1.0 2.1 1 1 2 3 3 3 3 IKI3 family eIF2A PF08662.11 RLN26970.1 - 0.0022 17.9 0.1 0.39 10.6 0.2 3.3 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Retinal PF15449.6 RLN26971.1 - 0.13 10.0 7.3 0.17 9.6 7.3 1.1 1 0 0 1 1 1 0 Retinal protein ThiD2 PF17792.1 RLN26972.1 - 0.0011 19.4 1.8 0.011 16.2 0.2 2.3 1 1 1 2 2 2 1 ThiD2 family Apolipoprotein PF01442.18 RLN26972.1 - 0.003 17.5 3.0 0.12 12.2 1.5 2.4 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain Tsc35 PF15079.6 RLN26972.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Testis-specific protein 35 ApoC-I PF04691.12 RLN26972.1 - 0.15 12.0 1.6 0.89 9.5 0.7 2.7 2 1 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) LOH1CR12 PF10158.9 RLN26972.1 - 0.17 11.9 0.2 4.3 7.4 0.1 2.2 1 1 1 2 2 2 0 Tumour suppressor protein ZapD PF07072.11 RLN26972.1 - 0.21 11.3 0.2 0.53 10.0 0.2 1.6 1 0 0 1 1 1 0 Cell division protein Prominin PF05478.11 RLN26972.1 - 0.34 8.8 1.1 0.44 8.4 1.1 1.1 1 0 0 1 1 1 0 Prominin Grg1 PF11034.8 RLN26972.1 - 0.95 9.7 9.6 5.4 7.3 0.4 4.0 3 1 0 3 3 3 0 Glucose-repressible protein Grg1 AAA PF00004.29 RLN26973.1 - 3.7e-14 53.3 0.0 7.4e-14 52.3 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 RLN26973.1 - 3.7e-13 49.6 0.0 3.2e-12 46.5 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 RLN26973.1 - 5.4e-09 36.2 0.0 9.7e-09 35.4 0.0 1.4 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 RLN26973.1 - 5e-07 30.1 0.0 9.1e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 RLN26973.1 - 1.2e-05 25.1 0.0 2.3e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 RLN26973.1 - 2e-05 25.1 0.0 3.6e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 RLN26973.1 - 0.00021 21.1 0.0 0.00031 20.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RLN26973.1 - 0.00054 19.8 0.0 0.00089 19.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 RLN26973.1 - 0.00076 19.5 1.5 0.018 15.0 0.2 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TniB PF05621.11 RLN26973.1 - 0.00079 18.9 0.0 0.0053 16.2 0.0 2.1 1 1 0 1 1 1 1 Bacterial TniB protein ResIII PF04851.15 RLN26973.1 - 0.00085 19.4 0.0 0.0046 17.0 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 RLN26973.1 - 0.00094 19.2 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 RLN26973.1 - 0.0011 18.7 0.1 0.12 12.0 0.0 2.2 1 1 1 2 2 2 1 IstB-like ATP binding protein DUF815 PF05673.13 RLN26973.1 - 0.0016 17.7 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 RLN26973.1 - 0.0019 17.9 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 RLN26973.1 - 0.0037 16.8 0.0 0.0063 16.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_19 PF13245.6 RLN26973.1 - 0.0045 17.3 0.0 0.012 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 RLN26973.1 - 0.0046 16.7 0.2 0.046 13.5 0.2 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase Mg_chelatase PF01078.21 RLN26973.1 - 0.0085 15.5 0.1 0.028 13.8 0.1 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 RLN26973.1 - 0.014 14.7 0.0 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 RLN26973.1 - 0.019 14.5 0.0 0.095 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 RLN26973.1 - 0.026 14.0 0.0 0.71 9.3 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.6 RLN26973.1 - 0.035 14.7 0.0 0.055 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 RLN26973.1 - 0.071 13.2 0.1 0.42 10.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 RLN26973.1 - 0.075 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Rep_fac_C PF08542.11 RLN26974.1 - 1.1e-15 57.8 0.0 2.2e-15 56.8 0.0 1.5 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_assoc_2 PF16193.5 RLN26974.1 - 0.0045 17.3 0.0 0.0071 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA C-terminal domain GTP_EFTU PF00009.27 RLN26975.1 - 6.7e-44 149.8 0.0 6.7e-44 149.8 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 RLN26975.1 - 8.1e-27 93.8 0.1 4.6e-26 91.3 0.0 2.4 3 0 0 3 3 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 RLN26975.1 - 5.7e-11 42.7 0.2 5.7e-11 42.7 0.2 2.5 3 0 0 3 3 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RLN26975.1 - 3.4e-05 23.9 0.1 0.00016 21.7 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF4746 PF15928.5 RLN26975.1 - 0.079 12.4 11.7 0.15 11.5 11.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) FeoB_N PF02421.18 RLN26975.1 - 0.11 12.0 0.0 8.2 5.9 0.0 3.0 3 0 0 3 3 3 0 Ferrous iron transport protein B PRCC PF10253.9 RLN26975.1 - 0.12 13.2 3.5 0.17 12.7 3.5 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting BUD22 PF09073.10 RLN26975.1 - 0.5 9.7 12.6 0.74 9.1 12.6 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 RLN26975.1 - 1.2 7.3 10.8 1.7 6.9 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 RLN26975.1 - 6.4 6.1 16.9 9.3 5.6 16.9 1.2 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 RLN26975.1 - 8 4.9 12.6 11 4.4 12.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 RLN26975.1 - 8.4 4.5 16.4 12 3.9 16.4 1.2 1 0 0 1 1 1 0 Nop14-like family CTP_transf_like PF01467.26 RLN27015.1 - 6.6e-06 26.4 0.0 2.9e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 Cytidylyltransferase-like CinA PF02464.17 RLN27015.1 - 0.0023 17.5 0.1 0.008 15.8 0.0 1.9 2 0 0 2 2 2 1 Competence-damaged protein IQ PF00612.27 RLN27016.1 - 8e-05 22.1 2.3 0.037 13.8 0.1 2.6 2 0 0 2 2 2 2 IQ calmodulin-binding motif Exo_endo_phos PF03372.23 RLN27016.1 - 0.00036 20.1 0.0 0.0011 18.6 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family C2 PF00168.30 RLN27017.1 - 1.3e-101 333.8 0.0 6.8e-16 58.4 0.0 9.2 9 0 0 9 9 9 8 C2 domain Ferlin_C PF16165.5 RLN27017.1 - 0.00011 22.1 2.3 0.00048 20.1 0.1 3.0 2 1 0 2 2 2 1 Ferlin C-terminus FerI PF08151.12 RLN27017.1 - 0.00063 19.8 0.0 0.0038 17.3 0.0 2.4 1 0 0 1 1 1 1 FerI (NUC094) domain RRN9 PF10680.9 RLN27017.1 - 0.15 12.3 0.2 0.46 10.8 0.2 1.8 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor CTP_transf_like PF01467.26 RLN27018.1 - 1.6e-05 25.1 0.0 7.7e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 Cytidylyltransferase-like CinA PF02464.17 RLN27018.1 - 0.0015 18.1 0.4 0.005 16.4 0.1 1.9 2 0 0 2 2 2 1 Competence-damaged protein Thioredoxin PF00085.20 RLN27020.1 - 2.3e-23 82.2 0.8 4.9e-23 81.1 0.8 1.6 1 0 0 1 1 1 1 Thioredoxin Evr1_Alr PF04777.13 RLN27020.1 - 3.5e-17 62.7 0.6 1.2e-16 60.9 0.6 2.0 1 0 0 1 1 1 1 Erv1 / Alr family OST3_OST6 PF04756.13 RLN27020.1 - 5.6e-05 22.6 0.2 5.6e-05 22.6 0.2 1.9 3 0 0 3 3 3 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 RLN27020.1 - 0.00076 19.8 0.3 0.0052 17.1 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.6 RLN27020.1 - 0.0028 17.8 0.1 0.0098 16.1 0.1 1.9 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 RLN27020.1 - 0.038 13.9 0.1 0.14 12.0 0.1 2.0 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 RLN27020.1 - 0.068 12.9 0.2 0.16 11.7 0.2 1.6 1 0 0 1 1 1 0 Redoxin Thioredoxin_4 PF13462.6 RLN27020.1 - 0.078 13.1 0.3 0.078 13.1 0.3 2.9 2 1 1 3 3 3 0 Thioredoxin Zn-ribbon_8 PF09723.10 RLN27020.1 - 0.34 11.1 3.9 28 4.9 0.1 3.4 3 0 0 3 3 3 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 RLN27020.1 - 0.42 10.6 4.2 8.3 6.5 0.0 3.4 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Thioredoxin PF00085.20 RLN27021.1 - 8.5e-21 73.9 0.1 1.6e-20 73.0 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Evr1_Alr PF04777.13 RLN27021.1 - 5.7e-20 71.6 0.6 1.4e-19 70.4 0.6 1.6 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin_4 PF13462.6 RLN27021.1 - 0.0098 16.1 0.4 0.039 14.1 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin TniQ PF06527.11 RLN27021.1 - 0.026 15.2 1.5 12 6.6 0.0 3.0 3 1 0 3 3 3 0 TniQ OST3_OST6 PF04756.13 RLN27021.1 - 0.03 13.7 0.1 0.059 12.7 0.0 1.5 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 RLN27021.1 - 0.041 14.2 0.0 0.095 13.0 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Zn_Tnp_IS1595 PF12760.7 RLN27021.1 - 0.05 13.6 4.5 1.1 9.3 0.0 3.4 3 0 0 3 3 3 0 Transposase zinc-ribbon domain RQC PF09382.10 RLN27021.1 - 0.082 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 RQC domain Thioredoxin PF00085.20 RLN27022.1 - 9.5e-19 67.3 0.1 1.7e-18 66.5 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Evr1_Alr PF04777.13 RLN27022.1 - 1.7e-17 63.7 0.2 4.5e-17 62.4 0.2 1.7 1 0 0 1 1 1 1 Erv1 / Alr family OST3_OST6 PF04756.13 RLN27022.1 - 2.8e-05 23.6 0.0 2.8e-05 23.6 0.0 2.1 3 0 0 3 3 3 1 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 RLN27022.1 - 0.0059 16.8 0.4 0.019 15.2 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 RLN27022.1 - 0.024 14.9 0.0 0.057 13.7 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like OppC_N PF12911.7 RLN27022.1 - 0.1 12.6 3.1 0.17 11.9 0.3 2.4 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Thioredoxin_2 PF13098.6 RLN27022.1 - 0.21 12.1 0.8 0.8 10.2 0.2 2.3 2 1 1 3 3 3 0 Thioredoxin-like domain Zn_Tnp_IS1595 PF12760.7 RLN27022.1 - 0.38 10.8 4.1 5.5 7.1 0.0 3.3 3 0 0 3 3 3 0 Transposase zinc-ribbon domain DOT1 PF08123.13 RLN27040.1 - 0.0015 18.1 0.0 0.051 13.1 0.0 2.6 1 1 0 1 1 1 1 Histone methylation protein DOT1 AsnC_trans_reg2 PF17805.1 RLN27040.1 - 0.16 12.1 0.6 0.57 10.4 0.2 2.0 1 1 1 2 2 2 0 AsnC-like ligand binding domain Dimer_Tnp_hAT PF05699.14 RLN27041.1 - 0.00043 20.0 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 RLN27041.1 - 0.018 15.1 0.1 0.063 13.3 0.1 2.1 1 0 0 1 1 1 0 BED zinc finger ECH_1 PF00378.20 RLN27042.1 - 2.8e-46 157.9 0.1 4.7e-34 117.8 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RLN27042.1 - 9.7e-20 71.3 0.5 8e-11 42.0 0.6 3.2 1 1 2 3 3 3 3 Enoyl-CoA hydratase/isomerase Ribosomal_L15e PF00827.17 RLN27043.1 - 1e-89 299.4 9.1 1.2e-89 299.2 9.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 UBA_6 PF18039.1 RLN27043.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain WD40 PF00400.32 RLN27044.1 - 2.5e-17 62.9 6.2 0.031 15.2 0.2 9.3 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN27044.1 - 0.16 12.3 0.0 2.6 8.4 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Sel1 PF08238.12 RLN27045.1 - 8.4e-14 51.7 36.8 1.9e-05 25.1 0.2 9.0 10 0 0 10 10 10 5 Sel1 repeat Laminin_G_3 PF13385.6 RLN27045.1 - 1.8e-07 31.4 0.0 3.6e-06 27.2 0.0 2.3 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily TPR_16 PF13432.6 RLN27045.1 - 0.39 11.4 32.5 0.083 13.5 2.3 6.8 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 RLN27045.1 - 0.69 10.3 2.4 55 4.3 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat adh_short PF00106.25 RLN27046.1 - 3.4e-22 78.9 0.1 5.4e-22 78.2 0.1 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN27046.1 - 6.7e-14 52.0 0.0 8.5e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN27046.1 - 0.038 13.9 0.2 0.063 13.2 0.2 1.3 1 0 0 1 1 1 0 KR domain IF4E PF01652.18 RLN27047.1 - 2.3e-10 40.5 0.5 2.8e-10 40.2 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E IF4E PF01652.18 RLN27048.1 - 5.3e-21 75.1 0.1 1e-20 74.2 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TSC22 PF01166.18 RLN27048.1 - 0.15 12.4 2.5 1.2 9.5 0.0 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family Atg14 PF10186.9 RLN27048.1 - 2.7 7.0 10.9 3.9 6.5 10.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Trimer_CC PF08954.11 RLN27048.1 - 4.4 6.9 10.3 7.4 6.2 1.5 2.9 2 1 1 3 3 3 0 Trimerisation motif HECT PF00632.25 RLN27049.1 - 3e-78 263.4 0.0 4.4e-78 262.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 RLN27049.1 - 0.04 13.2 0.1 0.075 12.4 0.1 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others DUF5325 PF17259.2 RLN27049.1 - 1.9 8.4 4.4 5 7.1 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5325) Adeno_E3_CR2 PF02439.15 RLN27049.1 - 4.2 7.2 7.9 3.6 7.4 4.5 2.2 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 C2 PF00168.30 RLN27050.1 - 1.7e-20 73.2 0.0 2.7e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 C2 domain GTF2I PF02946.14 RLN27095.1 - 0.0083 16.2 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 GTF2I-like repeat Apolipo_F PF15148.6 RLN27095.1 - 0.042 13.3 0.6 0.12 11.8 0.4 1.7 1 1 1 2 2 2 0 Apolipoprotein F AAA PF00004.29 RLN27098.1 - 2.3e-10 41.0 0.0 6.8e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 RLN27098.1 - 7.7e-06 26.0 0.1 0.0009 19.2 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 RLN27098.1 - 3e-05 24.6 0.2 0.00011 22.7 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 RLN27098.1 - 5.8e-05 23.1 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RLN27098.1 - 9.8e-05 22.6 0.1 0.0011 19.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 RLN27098.1 - 0.00021 21.4 0.0 0.001 19.3 0.0 2.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 RLN27098.1 - 0.00026 20.8 0.0 0.00051 19.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 RLN27098.1 - 0.00058 20.3 0.2 0.006 17.0 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 RLN27098.1 - 0.0016 18.4 0.0 0.0038 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 RLN27098.1 - 0.0017 17.6 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 RLN27098.1 - 0.0033 17.7 0.3 0.029 14.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RLN27098.1 - 0.0039 16.9 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 RLN27098.1 - 0.0041 16.7 0.1 0.85 9.2 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 RLN27098.1 - 0.011 15.5 0.0 0.055 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 RLN27098.1 - 0.011 16.2 0.0 0.057 13.9 0.0 2.2 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 RLN27098.1 - 0.035 14.6 0.1 0.11 12.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 RLN27098.1 - 0.036 14.4 0.0 0.086 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 RLN27098.1 - 0.04 14.3 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 RLN27098.1 - 0.052 13.1 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 RLN27098.1 - 0.061 12.8 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 RLN27098.1 - 0.063 13.0 0.0 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_assoc_2 PF16193.5 RLN27098.1 - 0.083 13.2 0.0 0.28 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA C-terminal domain IstB_IS21 PF01695.17 RLN27098.1 - 0.09 12.5 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 RLN27098.1 - 0.097 12.7 0.1 0.25 11.4 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 RLN27098.1 - 0.099 12.5 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase Costars PF14705.6 RLN27099.1 - 5.8e-22 77.6 0.2 6.8e-22 77.4 0.2 1.0 1 0 0 1 1 1 1 Costars DSPc PF00782.20 RLN27100.1 - 1.5e-18 66.9 0.0 2.9e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RLN27100.1 - 0.045 13.3 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 RLN27100.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain 2-Hacid_dh_C PF02826.19 RLN27101.1 - 2.1e-57 193.3 0.0 3.6e-57 192.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 RLN27101.1 - 1.3e-29 102.6 0.0 1.4e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 RLN27101.1 - 1.7e-06 28.3 0.0 5e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 RLN27101.1 - 0.0026 17.8 0.2 0.0055 16.8 0.0 1.5 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 RLN27101.1 - 0.007 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 RLN27101.1 - 0.0093 15.9 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN27101.1 - 0.067 12.5 0.1 2.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MMR_HSR1 PF01926.23 RLN27102.1 - 4e-10 39.8 0.0 8e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 RLN27102.1 - 1.1e-08 34.7 0.1 1.4e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 RLN27102.1 - 0.00037 20.4 0.1 0.0011 18.9 0.1 1.8 1 1 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 RLN27102.1 - 0.00041 20.9 0.0 0.00083 19.9 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 RLN27102.1 - 0.0019 18.6 0.1 0.0032 17.9 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 RLN27102.1 - 0.0041 17.2 2.1 0.13 12.4 0.2 2.9 2 1 2 4 4 4 1 Dynamin family AAA_29 PF13555.6 RLN27102.1 - 0.0043 16.8 0.1 0.0083 15.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FeoB_N PF02421.18 RLN27102.1 - 0.0077 15.8 0.3 0.014 14.9 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B FtsK_SpoIIIE PF01580.18 RLN27102.1 - 0.02 14.3 0.2 0.057 12.8 0.0 1.8 2 1 1 3 3 3 0 FtsK/SpoIIIE family AAA PF00004.29 RLN27102.1 - 0.029 14.8 0.1 0.073 13.5 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 RLN27102.1 - 0.034 13.9 0.3 6.7 6.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain SRPRB PF09439.10 RLN27102.1 - 0.043 13.2 0.0 0.093 12.2 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 RLN27102.1 - 0.054 12.8 0.1 0.17 11.2 0.1 1.9 1 1 1 2 2 2 0 Septin AAA_28 PF13521.6 RLN27102.1 - 0.085 13.1 1.1 2.1 8.6 0.1 2.5 2 1 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 RLN27102.1 - 0.088 12.5 0.1 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.6 RLN27102.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 RLN27102.1 - 0.15 12.4 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ADH_zinc_N PF00107.26 RLN27103.1 - 1.8e-25 89.4 0.7 4.4e-25 88.1 0.4 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN27103.1 - 5.6e-15 56.6 0.0 1.3e-14 55.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN27103.1 - 2e-08 34.1 0.1 9.4e-08 31.9 0.1 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CutC PF03932.14 RLN27103.1 - 0.068 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 CutC family SAM_adeno_trans PF01887.16 RLN27107.1 - 0.056 12.9 0.2 4.5 6.6 0.1 2.3 1 1 1 2 2 2 0 S-adenosyl-l-methionine hydroxide adenosyltransferase Glyco_hydro2_C5 PF18565.1 RLN27107.1 - 0.38 10.6 9.1 11 5.9 0.3 3.7 2 1 1 3 3 3 0 Glycoside hydrolase family 2 C-terminal domain 5 Big_1 PF02369.16 RLN27107.1 - 1.7 8.7 16.4 2.4 8.2 2.2 3.7 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) MucBP PF06458.12 RLN27107.1 - 5.1 8.2 13.6 7.3 7.7 0.4 3.7 4 0 0 4 4 4 0 MucBP domain SSP160 PF06933.11 RLN27107.1 - 8 4.5 10.1 2.9 6.0 1.4 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 XRCC4 PF06632.12 RLN27108.1 - 3e-08 32.9 2.4 4.6e-08 32.3 2.4 1.3 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Pox_Ag35 PF03286.14 RLN27108.1 - 0.25 11.1 10.0 0.053 13.3 6.0 1.9 1 1 0 1 1 1 0 Pox virus Ag35 surface protein PKcGMP_CC PF16808.5 RLN27108.1 - 7.1 6.6 9.7 2.6 8.0 4.7 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Furin-like_2 PF15913.5 RLN27120.1 - 0.00015 21.9 6.9 0.00016 21.8 6.9 1.1 1 0 0 1 1 1 1 Furin-like repeat, cysteine-rich Dickkopf_N PF04706.12 RLN27120.1 - 0.062 13.8 9.4 0.23 12.0 9.4 1.9 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Stig1 PF04885.13 RLN27120.1 - 0.15 12.6 10.8 0.18 12.3 10.8 1.2 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 GST_N_3 PF13417.6 RLN27121.1 - 4.5e-14 52.6 0.3 8.6e-14 51.7 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 RLN27121.1 - 9.7e-11 41.7 3.2 9.7e-11 41.7 3.2 2.6 3 1 0 3 3 3 1 Glutaredoxin GST_N_2 PF13409.6 RLN27121.1 - 1.3e-07 31.8 0.1 2.3e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 RLN27121.1 - 6.7e-06 26.8 0.1 1.8e-05 25.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_N PF02798.20 RLN27121.1 - 1.4e-05 25.3 0.0 3.4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN27121.1 - 5.4e-05 23.1 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF836 PF05768.14 RLN27121.1 - 0.1 13.0 0.9 0.24 11.8 0.2 2.0 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) DUF4813 PF16072.5 RLN27121.1 - 0.22 11.1 7.8 0.31 10.7 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) ADP_PFK_GK PF04587.15 RLN27122.1 - 3.7e-97 325.6 0.0 5.3e-97 325.1 0.0 1.3 1 1 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region MatE PF01554.18 RLN27122.1 - 0.069 12.8 0.4 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 MatE FGAR-AT_N PF18076.1 RLN27123.1 - 4.9e-20 71.6 0.1 9.5e-20 70.7 0.1 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal AIRS_C PF02769.22 RLN27123.1 - 8e-15 55.3 0.0 2.1e-14 54.0 0.0 1.7 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain FGAR-AT_linker PF18072.1 RLN27123.1 - 2e-10 41.1 0.0 5.7e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 RLN27123.1 - 0.0075 16.9 0.0 0.015 15.9 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Tannase PF07519.11 RLN27125.1 - 6.1e-116 388.1 0.0 1.1e-70 238.9 0.0 2.1 2 0 0 2 2 2 2 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 RLN27125.1 - 0.015 14.8 0.1 0.071 12.6 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF3527 PF12043.8 RLN27140.1 - 0.18 11.3 5.7 0.36 10.3 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) DDHD PF02862.17 RLN27140.1 - 0.5 10.5 4.6 0.4 10.8 1.2 2.2 2 0 0 2 2 2 0 DDHD domain Presenilin PF01080.17 RLN27140.1 - 0.91 8.2 19.8 0.48 9.1 12.1 2.2 2 0 0 2 2 2 0 Presenilin FAM60A PF15396.6 RLN27140.1 - 1.2 9.1 8.3 0.14 12.1 1.5 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Pro_CA PF00484.19 RLN27140.1 - 1.3 9.3 5.2 2 8.7 1.5 2.4 2 0 0 2 2 2 0 Carbonic anhydrase GPCR_chapero_1 PF11904.8 RLN27140.1 - 2.6 7.4 14.1 0.011 15.2 4.1 2.0 3 0 0 3 3 3 0 GPCR-chaperone Paramyxo_ncap PF00973.19 RLN27140.1 - 6.7 5.5 6.9 16 4.2 6.9 1.6 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein eIF-3_zeta PF05091.12 RLN27140.1 - 6.9 5.5 11.9 0.15 11.0 5.2 1.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TetR_C_30 PF17939.1 RLN27160.1 - 0.71 10.1 4.8 2 8.7 2.2 2.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Ank_2 PF12796.7 RLN27212.1 - 3e-113 370.6 15.6 1.9e-15 57.2 0.1 8.3 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.30 RLN27212.1 - 4.7e-95 308.2 21.8 2.2e-06 27.9 0.0 15.4 15 0 0 15 15 15 15 Ankyrin repeat Ank_3 PF13606.6 RLN27212.1 - 5.8e-91 287.4 15.9 1.2e-06 28.3 0.0 15.7 16 0 0 16 16 16 15 Ankyrin repeat Ank_4 PF13637.6 RLN27212.1 - 4.3e-84 275.9 24.8 5.9e-10 39.5 0.0 12.9 3 3 8 13 13 13 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN27212.1 - 6.3e-78 255.8 35.5 1.8e-08 34.5 0.2 13.6 1 1 12 14 14 14 14 Ankyrin repeats (many copies) Nepo_coat_C PF03688.14 RLN27212.1 - 0.0014 18.5 2.1 5.9 6.7 0.1 5.0 2 1 3 6 6 6 1 Nepovirus coat protein, C-terminal domain YlzJ PF14035.6 RLN27212.1 - 0.0026 17.9 0.0 1.7e+02 2.5 0.0 6.1 8 0 0 8 8 6 0 YlzJ-like protein tRNA_NucTran2_2 PF13735.6 RLN27212.1 - 0.0084 16.1 0.3 4.8 7.1 0.0 3.0 2 1 0 2 2 2 2 tRNA nucleotidyltransferase domain 2 putative DUF2390 PF09523.10 RLN27212.1 - 0.017 15.4 3.8 19 5.6 0.0 4.8 3 1 3 6 6 6 0 Protein of unknown function (DUF2390) MEDS PF14417.6 RLN27212.1 - 0.036 13.9 3.4 17 5.2 0.0 4.2 3 1 2 5 5 5 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Imm_superinfect PF14373.6 RLN27212.1 - 0.055 13.4 16.3 14 5.7 0.0 9.2 11 0 0 11 11 11 0 Superinfection immunity protein PK_C PF02887.16 RLN27212.1 - 0.064 13.5 0.5 48 4.2 0.0 4.1 2 2 3 5 5 5 0 Pyruvate kinase, alpha/beta domain VWA_3_C PF18571.1 RLN27212.1 - 0.51 10.3 12.8 1.3e+02 2.6 0.0 7.9 10 0 0 10 10 10 0 von Willebrand factor type A C-terminal domain IgaA PF07095.11 RLN27212.1 - 8.1 4.3 7.5 17 3.3 0.1 3.6 4 1 1 5 5 5 0 Intracellular growth attenuator protein IgaA ABC_membrane PF00664.23 RLN27219.1 - 4e-53 180.8 9.0 5.5e-53 180.4 9.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region EAP30 PF04157.16 RLN27220.1 - 2.9e-59 200.2 0.1 3.3e-59 200.0 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Arf PF00025.21 RLN27221.1 - 3.9e-40 137.2 0.0 4.5e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 RLN27221.1 - 7.9e-06 25.3 0.0 1.3e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit Ras PF00071.22 RLN27221.1 - 0.00016 21.3 0.0 0.00017 21.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN27221.1 - 0.0021 18.3 0.0 0.003 17.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 RLN27221.1 - 0.063 12.8 0.0 0.07 12.7 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain EF-hand_8 PF13833.6 RLN27222.1 - 2.3e-11 43.3 2.2 3.5e-07 30.0 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain pair Arm PF00514.23 RLN27222.1 - 2.8e-10 39.9 77.4 0.00012 22.0 0.3 20.6 23 0 0 23 23 23 6 Armadillo/beta-catenin-like repeat EF-hand_6 PF13405.6 RLN27222.1 - 1.1e-06 28.1 0.5 0.054 13.4 0.0 3.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RLN27222.1 - 1.8e-06 27.1 0.6 0.0019 17.6 0.3 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RLN27222.1 - 5.8e-06 26.7 1.3 3.4e-05 24.2 0.3 2.7 2 0 0 2 2 2 1 EF-hand domain pair HEAT_2 PF13646.6 RLN27222.1 - 0.00011 22.6 1.4 0.00011 22.6 1.4 14.3 13 3 2 15 15 15 1 HEAT repeats Cnd1 PF12717.7 RLN27222.1 - 0.0082 16.2 2.5 6.8 6.7 0.0 5.7 5 1 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RLN27222.1 - 0.02 15.1 29.8 0.3 11.5 0.5 11.8 10 0 0 10 10 10 0 HEAT repeat RTP1_C1 PF10363.9 RLN27222.1 - 0.19 11.9 2.2 11 6.2 0.3 4.5 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 EF-hand_5 PF13202.6 RLN27222.1 - 0.39 10.3 2.2 0.55 9.8 0.2 2.3 2 0 0 2 2 2 0 EF hand Acyltransferase PF01553.21 RLN27223.1 - 1e-22 80.2 0.0 3.9e-22 78.3 0.0 1.8 1 1 1 2 2 2 1 Acyltransferase Acyltransf_C PF16076.5 RLN27223.1 - 2.2e-09 37.3 0.0 4.3e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus p450 PF00067.22 RLN27224.1 - 4.1e-27 95.1 0.0 2.7e-15 56.1 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Ank_2 PF12796.7 RLN27225.1 - 3.2e-28 98.1 1.7 3.7e-10 40.3 0.6 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN27225.1 - 8e-16 58.2 0.0 2.3e-05 24.9 0.0 3.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN27225.1 - 2.2e-15 55.2 0.1 0.0042 17.5 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 RLN27225.1 - 5.2e-15 55.3 1.3 1.8e-05 24.9 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN27225.1 - 1.4e-10 41.1 0.3 0.097 13.2 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Sugar_tr PF00083.24 RLN27229.1 - 9.8e-72 242.2 20.4 1.2e-71 241.9 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN27229.1 - 1.3e-22 80.2 24.8 2.7e-22 79.2 24.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 RLN27229.1 - 0.069 11.5 10.8 0.033 12.6 4.0 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Auto_anti-p27 PF06677.12 RLN27230.1 - 0.0011 19.1 0.1 0.0018 18.4 0.1 1.3 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Pox_G7 PF05503.12 RLN27230.1 - 0.018 14.0 0.4 0.019 13.9 0.4 1.1 1 0 0 1 1 1 0 Poxvirus G7-like eIF3_subunit PF08597.10 RLN27230.1 - 0.051 13.5 10.7 0.056 13.4 10.7 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit P5-ATPase PF12409.8 RLN27230.1 - 0.085 13.0 0.8 0.1 12.7 0.8 1.1 1 0 0 1 1 1 0 P5-type ATPase cation transporter Hemocyanin_M PF00372.19 RLN27230.1 - 0.1 11.8 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Hemocyanin, copper containing domain Fe-ADH_2 PF13685.6 RLN27230.1 - 0.15 11.7 0.7 0.19 11.4 0.7 1.0 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase DUF4407 PF14362.6 RLN27230.1 - 0.38 10.1 10.5 0.48 9.7 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Saw1 PF11561.8 RLN27230.1 - 0.58 9.6 3.6 0.68 9.4 3.6 1.1 1 0 0 1 1 1 0 Single strand annealing-weakened 1 V_ATPase_I PF01496.19 RLN27230.1 - 1.4 6.7 4.2 1.5 6.7 4.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2058 PF09831.9 RLN27230.1 - 3.1 7.9 16.6 3.7 7.7 16.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) TERB2 PF15101.6 RLN27230.1 - 5 7.1 7.4 6.1 6.8 7.4 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 AAA PF00004.29 RLN27232.1 - 8.5e-41 139.5 0.0 1.4e-40 138.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RLN27232.1 - 5.5e-13 48.5 0.1 1.2e-12 47.4 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 RLN27232.1 - 9.3e-11 41.5 0.1 2.8e-10 40.0 0.1 1.9 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 RLN27232.1 - 6.3e-07 29.9 0.0 0.0005 20.5 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 RLN27232.1 - 1.9e-05 24.9 0.0 4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 RLN27232.1 - 6.6e-05 23.2 0.1 0.046 14.0 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 RLN27232.1 - 0.0001 22.3 0.2 0.0011 18.9 0.2 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RLN27232.1 - 0.00013 21.8 0.0 0.00032 20.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 RLN27232.1 - 0.0016 18.8 0.0 0.0037 17.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Prot_ATP_OB_N PF17758.1 RLN27232.1 - 0.0018 17.9 0.3 0.0069 16.0 0.0 2.1 3 0 0 3 3 1 1 Proteasomal ATPase OB N-terminal domain IstB_IS21 PF01695.17 RLN27232.1 - 0.0026 17.5 0.0 0.0055 16.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 RLN27232.1 - 0.0029 16.8 0.0 0.0057 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 RLN27232.1 - 0.004 16.6 0.0 0.0073 15.7 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 RLN27232.1 - 0.0047 17.5 0.1 0.021 15.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 RLN27232.1 - 0.0067 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 RLN27232.1 - 0.0095 15.5 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 RLN27232.1 - 0.01 15.2 0.1 0.1 11.9 0.0 2.4 3 0 0 3 3 3 0 KaiC AAA_28 PF13521.6 RLN27232.1 - 0.013 15.8 0.0 0.029 14.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 RLN27232.1 - 0.014 14.9 0.0 0.038 13.5 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 RLN27232.1 - 0.023 14.8 0.0 0.052 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RLN27232.1 - 0.03 14.1 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 RLN27232.1 - 0.035 13.8 0.0 0.11 12.2 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 RLN27232.1 - 0.038 13.4 0.1 0.071 12.6 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_3 PF07726.11 RLN27232.1 - 0.05 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 RLN27232.1 - 0.053 13.5 0.0 0.14 12.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 RLN27232.1 - 0.066 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 RLN27232.1 - 0.067 12.3 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 RLN27232.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.8 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 RLN27232.1 - 0.18 11.5 0.0 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pro_isomerase PF00160.21 RLN27233.1 - 4.9e-27 95.1 0.0 7.2e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_10 PF13374.6 RLN27233.1 - 2.8 7.9 5.4 0.58 10.1 0.6 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Zip PF02535.22 RLN27234.1 - 0.12 11.5 3.0 0.78 8.9 0.4 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter RRN3 PF05327.11 RLN27234.1 - 0.43 9.1 2.6 6.2 5.2 0.3 2.1 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Myc_N PF01056.18 RLN27234.1 - 2.3 8.0 9.0 0.24 11.2 1.2 2.2 2 0 0 2 2 2 0 Myc amino-terminal region RNase_H2_suC PF08615.11 RLN27235.1 - 4.5e-12 46.3 0.0 6.6e-12 45.8 0.0 1.3 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) HAD_2 PF13419.6 RLN27236.1 - 8.9e-26 91.0 0.0 4.7e-25 88.7 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RLN27236.1 - 2.1e-13 51.1 0.0 7.4e-08 32.9 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 RLN27236.1 - 1.7e-09 38.3 0.0 2.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RLN27236.1 - 0.0014 18.7 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 RLN27236.1 - 0.0058 16.7 0.1 0.11 12.6 0.1 2.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase PRP9_N PF16958.5 RLN27237.1 - 0.32 11.0 4.6 0.91 9.5 1.2 2.6 2 0 0 2 2 2 0 Pre-mRNA-splicing factor PRP9 N-terminus WD40 PF00400.32 RLN27238.1 - 2.2e-29 101.1 12.9 1.9e-07 31.6 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 RLN27238.1 - 2.8e-29 101.1 0.9 1.1e-27 96.0 0.1 3.4 3 1 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.11 RLN27238.1 - 1e-06 28.8 1.0 0.0011 18.9 0.1 3.4 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 RLN27238.1 - 2.3e-05 24.6 0.9 0.023 15.0 0.0 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain E1_dh PF00676.20 RLN27239.1 - 1.3e-83 280.4 0.0 1.8e-83 280.0 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 RLN27239.1 - 1.7e-05 24.6 0.0 0.00027 20.8 0.0 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 RLN27239.1 - 0.0034 16.6 0.0 0.0099 15.1 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.10 RLN27239.1 - 0.06 12.2 0.0 0.085 11.6 0.0 1.2 1 0 0 1 1 1 0 XFP N-terminal domain Aldo_ket_red PF00248.21 RLN27277.1 - 1.1e-38 133.1 0.0 1.3e-38 132.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DDE_Tnp_ISL3 PF01610.17 RLN27278.1 - 0.06 13.0 0.4 0.11 12.1 0.1 1.6 1 1 0 1 1 1 0 Transposase ADH_N PF08240.12 RLN27280.1 - 1.1e-25 89.6 1.4 1.1e-25 89.6 1.4 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN27280.1 - 7.3e-16 58.3 0.0 1.3e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN27280.1 - 0.00016 21.1 0.0 0.00027 20.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN27280.1 - 0.017 14.4 0.1 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ribosomal_S5 PF00333.20 RLN27280.1 - 0.038 14.0 0.1 0.038 14.0 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein S5, N-terminal domain ABC_tran PF00005.27 RLN27281.1 - 1.7e-46 158.1 0.0 1.7e-25 90.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 RLN27281.1 - 1.5e-41 142.9 26.3 1.9e-23 83.5 2.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region MMR_HSR1 PF01926.23 RLN27281.1 - 2.5e-06 27.6 0.0 0.032 14.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 RLN27281.1 - 3.2e-06 26.7 7.8 0.0038 16.7 2.5 4.0 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RLN27281.1 - 0.00011 22.7 0.0 0.073 13.4 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 RLN27281.1 - 0.00038 20.4 0.9 0.35 10.8 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 RLN27281.1 - 0.0026 17.8 0.9 2.6 8.1 0.1 2.8 2 1 0 2 2 2 2 Dynamin family AAA_22 PF13401.6 RLN27281.1 - 0.0036 17.6 1.3 1.2 9.4 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 RLN27281.1 - 0.0067 16.2 1.6 1.9 8.3 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 RLN27281.1 - 0.01 16.4 0.0 4.9 7.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 RLN27281.1 - 0.013 15.3 3.0 1.1 9.0 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_25 PF13481.6 RLN27281.1 - 0.021 14.4 0.2 0.86 9.1 0.1 2.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RLN27281.1 - 0.029 14.7 0.1 6.2 7.3 0.0 3.2 3 0 0 3 3 3 0 RNA helicase DUF815 PF05673.13 RLN27281.1 - 0.059 12.5 0.4 3.4 6.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DEAD PF00270.29 RLN27281.1 - 0.069 12.9 0.3 0.36 10.6 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_21 PF13304.6 RLN27281.1 - 0.072 12.9 0.1 8.2 6.1 0.1 3.4 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 RLN27281.1 - 0.079 12.2 0.0 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin PIG-P PF08510.12 RLN27281.1 - 0.11 12.4 0.3 0.5 10.3 0.3 2.2 1 0 0 1 1 1 0 PIG-P AAA_7 PF12775.7 RLN27281.1 - 0.12 11.9 0.2 7.3 6.1 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 RLN27281.1 - 0.13 12.8 1.2 2.5 8.5 0.1 2.5 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.17 RLN27281.1 - 0.18 11.9 1.6 0.47 10.5 0.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain CoaE PF01121.20 RLN27281.1 - 9.9 5.8 7.3 2.4 7.8 0.0 3.5 4 0 0 4 4 4 0 Dephospho-CoA kinase Dimer_Tnp_hAT PF05699.14 RLN27282.1 - 0.047 13.5 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Lipoprotein_2 PF00921.17 RLN27284.1 - 0.037 13.6 0.5 0.11 12.0 0.5 1.7 1 0 0 1 1 1 0 Borrelia lipoprotein TAXi_N PF14543.6 RLN27284.1 - 1 9.6 12.2 1.3 9.2 2.7 2.4 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal DNA_pol_phi PF04931.13 RLN27284.1 - 8.7 4.3 18.7 15 3.5 18.7 1.4 1 0 0 1 1 1 0 DNA polymerase phi RRM_1 PF00076.22 RLN27287.1 - 0.0018 18.0 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HalX PF08663.10 RLN27287.1 - 0.015 15.6 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 HalX domain DUF1932 PF09130.11 RLN27290.1 - 0.016 15.2 0.0 0.045 13.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) DUF5511 PF17630.2 RLN27290.1 - 0.1 12.8 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5511) eIF-1a PF01176.19 RLN27291.1 - 1.9e-11 43.6 0.1 3.2e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 TPR_2 PF07719.17 RLN27293.1 - 0.26 11.5 6.9 1.5 9.1 1.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat LUC7 PF03194.15 RLN27293.1 - 1.6 8.4 14.6 0.52 9.9 0.3 3.2 3 0 0 3 3 3 0 LUC7 N_terminus CP12 PF02672.15 RLN27293.1 - 3.8 8.3 5.6 63 4.4 0.4 3.6 4 0 0 4 4 4 0 CP12 domain C2-C2_1 PF11618.8 RLN27294.1 - 7.9e-36 123.2 0.0 3e-34 118.1 0.0 2.6 2 0 0 2 2 2 1 First C2 domain of RPGR-interacting protein 1 EF-hand_8 PF13833.6 RLN27294.1 - 1.1e-10 41.2 15.3 0.02 14.8 0.0 9.1 10 0 0 10 10 10 3 EF-hand domain pair EF-hand_6 PF13405.6 RLN27294.1 - 3.1e-09 36.0 8.6 0.022 14.7 0.0 8.3 9 0 0 9 9 9 2 EF-hand domain EF-hand_7 PF13499.6 RLN27294.1 - 9.9e-09 35.5 6.9 1.5 9.3 0.0 9.1 11 0 0 11 11 10 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN27294.1 - 5.6e-08 31.8 0.7 2.2 8.0 0.0 7.6 7 0 0 7 7 7 1 EF hand C2 PF00168.30 RLN27294.1 - 4.7e-07 30.1 0.0 0.0057 16.9 0.0 2.9 2 0 0 2 2 2 2 C2 domain EF-hand_11 PF08976.11 RLN27294.1 - 1.1e-05 26.3 0.1 1.5 9.8 0.0 5.7 6 0 0 6 6 4 1 EF-hand domain EF-hand_5 PF13202.6 RLN27294.1 - 0.11 12.1 0.1 39 4.0 0.0 3.6 2 0 0 2 2 2 0 EF hand HEPN_Toprim_N PF18871.1 RLN27294.1 - 0.32 10.9 0.0 0.32 10.9 0.0 2.3 3 0 0 3 3 3 0 HEPN/Toprim N-terminal domain 1 Speriolin_C PF15059.6 RLN27294.1 - 0.4 10.8 6.4 15 5.7 0.0 3.0 2 0 0 2 2 2 0 Speriolin C-terminus Gti1_Pac2 PF09729.9 RLN27294.1 - 1.2 9.2 8.9 3 7.9 8.9 1.6 1 0 0 1 1 1 0 Gti1/Pac2 family DUF1192 PF06698.11 RLN27294.1 - 1.9 8.6 5.4 0.96 9.6 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) WD40 PF00400.32 RLN27295.1 - 2.7e-20 72.3 0.7 1.3e-08 35.3 0.2 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN27295.1 - 7.7e-07 29.3 0.4 0.0027 18.0 0.0 2.7 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RLN27295.1 - 0.00011 21.6 0.0 0.091 12.1 0.0 2.2 1 1 1 2 2 2 2 WD40-like domain DAGK_cat PF00781.24 RLN27295.1 - 0.00056 19.5 0.3 0.0014 18.2 0.0 1.8 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain eIF2A PF08662.11 RLN27295.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 RLN27295.1 - 0.18 10.7 0.8 0.71 8.7 0.3 1.9 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain PHD PF00628.29 RLN27297.1 - 6.6e-12 45.1 27.5 1.1e-08 34.8 5.5 4.1 4 0 0 4 4 4 2 PHD-finger zf-HC5HC2H PF13771.6 RLN27297.1 - 8.6e-08 32.3 7.1 0.00075 19.7 0.9 2.8 2 1 0 2 2 2 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 RLN27297.1 - 0.00062 19.9 10.7 0.048 13.8 2.8 2.7 2 1 0 2 2 2 2 PHD-zinc-finger like domain FANCL_C PF11793.8 RLN27297.1 - 0.0025 18.0 6.5 0.49 10.6 2.2 3.0 2 0 0 2 2 2 2 FANCL C-terminal domain zf-PHD-like PF15446.6 RLN27297.1 - 0.016 14.8 19.5 0.14 11.7 2.6 3.8 4 0 0 4 4 4 0 PHD/FYVE-zinc-finger like domain ZapB PF06005.12 RLN27298.1 - 0.018 15.5 1.0 0.018 15.5 1.0 7.1 4 2 1 5 5 5 0 Cell division protein ZapB Trypsin_2 PF13365.6 RLN27299.1 - 1.4e-17 65.0 1.0 2.6e-17 64.1 1.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S46 PF10459.9 RLN27299.1 - 0.045 12.4 0.1 0.045 12.4 0.1 1.4 2 0 0 2 2 2 0 Peptidase S46 DEAD PF00270.29 RLN27300.1 - 4.7e-16 59.0 0.0 9.4e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN27300.1 - 2.4e-15 56.8 0.0 1e-14 54.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 RLN27300.1 - 1e-10 42.2 0.3 3.7e-10 40.4 0.3 2.1 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 RLN27300.1 - 0.00012 22.1 0.0 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RLN27300.1 - 0.067 13.5 0.1 0.35 11.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain PRP38_assoc PF12871.7 RLN27301.1 - 0.033 14.8 44.4 0.048 14.3 44.4 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term IF4E PF01652.18 RLN27302.1 - 1.9e-24 86.2 3.6 6.8e-13 48.7 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic initiation factor 4E Uds1 PF15456.6 RLN27302.1 - 0.29 11.3 1.8 0.35 11.0 0.9 1.6 2 0 0 2 2 2 0 Up-regulated During Septation MULE PF10551.9 RLN27303.1 - 3.1e-07 30.7 0.0 4.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 MULE transposase domain Pkinase_Tyr PF07714.17 RLN27334.1 - 2.7e-136 452.9 0.0 4.7e-39 134.2 0.0 4.2 4 0 0 4 4 4 4 Protein tyrosine kinase Pkinase PF00069.25 RLN27334.1 - 2.2e-129 430.4 0.0 7.7e-36 123.8 0.0 4.2 4 0 0 4 4 4 4 Protein kinase domain Kinase-like PF14531.6 RLN27334.1 - 4.5e-11 42.6 0.0 7.2e-05 22.2 0.0 3.5 3 0 0 3 3 3 3 Kinase-like APH PF01636.23 RLN27334.1 - 9.4e-08 32.3 7.4 0.0081 16.1 0.1 5.5 5 1 0 5 5 5 2 Phosphotransferase enzyme family Kdo PF06293.14 RLN27334.1 - 2.1e-07 30.5 0.1 0.11 11.8 0.1 4.3 4 0 0 4 4 4 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RLN27334.1 - 5.4e-06 26.1 0.0 0.1 12.2 0.0 3.6 3 0 0 3 3 3 2 RIO1 family Haspin_kinase PF12330.8 RLN27334.1 - 0.012 14.5 0.0 0.43 9.5 0.0 2.9 3 0 0 3 3 3 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 RLN27334.1 - 0.023 13.7 0.2 3.9 6.4 0.1 2.4 2 0 0 2 2 2 0 Seadornavirus VP7 EcKinase PF02958.20 RLN27334.1 - 0.14 11.5 0.0 25 4.0 0.0 3.0 3 0 0 3 3 3 0 Ecdysteroid kinase Pkinase_Tyr PF07714.17 RLN27335.1 - 3.5e-39 134.7 0.0 5.5e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN27335.1 - 1.1e-32 113.5 0.0 2.8e-32 112.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain DZR PF12773.7 RLN27335.1 - 0.00027 20.9 0.3 0.0006 19.8 0.3 1.5 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 RLN27335.1 - 0.00043 21.0 0.2 0.00097 19.8 0.2 1.6 1 0 0 1 1 1 1 zinc-ribbon family zinc_ribbon_2 PF13240.6 RLN27335.1 - 0.0007 19.2 2.3 0.0018 18.0 2.3 1.7 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 RLN27335.1 - 0.0022 17.3 1.0 0.0055 16.1 1.0 1.7 1 0 0 1 1 1 1 zinc-ribbon domain RIO1 PF01163.22 RLN27335.1 - 0.023 14.3 0.0 0.52 9.9 0.0 2.4 2 0 0 2 2 2 0 RIO1 family Pkinase_Tyr PF07714.17 RLN27337.1 - 3.9e-41 141.0 0.0 8e-41 140.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN27337.1 - 1.2e-36 126.5 0.0 2.7e-36 125.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain DZR PF12773.7 RLN27337.1 - 1e-07 31.9 23.8 0.00017 21.5 12.0 2.8 1 1 2 3 3 3 3 Double zinc ribbon UPF0547 PF10571.9 RLN27337.1 - 0.00027 21.0 1.4 0.00027 21.0 1.4 3.3 3 0 0 3 3 3 2 Uncharacterised protein family UPF0547 zinc_ribbon_15 PF17032.5 RLN27337.1 - 0.0062 17.3 24.9 0.011 16.5 0.3 3.4 2 1 1 3 3 3 1 zinc-ribbon family zinc_ribbon_2 PF13240.6 RLN27337.1 - 0.037 13.7 0.5 0.037 13.7 0.5 5.0 3 2 3 6 6 6 0 zinc-ribbon domain SesA PF17107.5 RLN27337.1 - 0.044 14.0 0.4 0.11 12.6 0.1 1.9 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases ADH_N PF08240.12 RLN27337.1 - 1.1 9.2 5.6 0.62 10.0 2.4 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain Spore_GerAC PF05504.11 RLN27337.1 - 5.4 7.2 7.1 4.5 7.5 4.5 2.0 1 1 1 2 2 2 0 Spore germination B3/ GerAC like, C-terminal Csd3_N PF18059.1 RLN27338.1 - 0.029 14.9 0.3 0.065 13.8 0.3 1.7 1 1 0 1 1 1 0 Csd3 N-terminal Cue1_U7BR PF18499.1 RLN27338.1 - 0.075 13.1 0.3 4.6 7.4 0.1 2.4 2 0 0 2 2 2 0 Ubc7p-binding region of Cue1 Toxin_36 PF10550.9 RLN27338.1 - 0.26 12.7 2.5 1.8 10.1 0.2 2.6 2 0 0 2 2 2 0 Conantokin-G mollusc-toxin Alg14 PF08660.11 RLN27340.1 - 4.4e-38 131.0 0.1 3e-23 82.6 0.1 2.2 2 0 0 2 2 2 2 Oligosaccharide biosynthesis protein Alg14 like CN_hydrolase PF00795.22 RLN27341.1 - 1.1e-30 106.9 0.0 1.3e-30 106.6 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PBP1_TM PF14812.6 RLN27342.1 - 0.045 14.1 7.2 0.09 13.2 7.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FRG2 PF15315.6 RLN27342.1 - 1.8 8.7 8.4 2.8 8.1 8.4 1.2 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 MAPEG PF01124.18 RLN27343.1 - 2.2e-15 56.7 0.0 3e-15 56.3 0.0 1.3 1 1 0 1 1 1 1 MAPEG family MAPEG PF01124.18 RLN27344.1 - 2.7e-30 104.9 1.0 6.5e-15 55.2 0.1 2.3 2 0 0 2 2 2 2 MAPEG family PIG-F PF06699.11 RLN27344.1 - 0.0064 16.7 0.1 0.36 11.0 0.0 2.2 2 0 0 2 2 2 2 GPI biosynthesis protein family Pig-F ELYS-bb PF16687.5 RLN27344.1 - 0.0096 14.6 0.1 0.016 13.9 0.0 1.4 2 0 0 2 2 2 1 beta-propeller of ELYS nucleoporin MAPEG PF01124.18 RLN27345.1 - 1.2e-24 86.7 0.0 1.2e-14 54.3 0.1 2.2 2 0 0 2 2 2 2 MAPEG family HupE_UreJ PF04955.12 RLN27345.1 - 0.0073 15.8 2.1 0.18 11.3 0.0 2.2 2 0 0 2 2 2 2 HupE / UreJ protein Sec8_exocyst PF04048.14 RLN27345.1 - 0.086 12.7 0.0 5.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Tim17 PF02466.19 RLN27346.1 - 7.7e-22 77.8 0.9 9.5e-22 77.5 0.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.9 RLN27346.1 - 0.07 13.5 0.2 0.07 13.5 0.2 1.7 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 adh_short_C2 PF13561.6 RLN27347.1 - 3.3e-45 154.5 1.7 4.9e-45 153.9 1.7 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RLN27347.1 - 3e-32 111.7 0.7 4.9e-32 111.0 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Pex14_N PF04695.13 RLN27347.1 - 3.9e-16 60.1 1.8 3.9e-16 60.1 1.8 2.0 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region KR PF08659.10 RLN27347.1 - 0.00047 20.1 0.1 0.00072 19.5 0.1 1.4 1 1 0 1 1 1 1 KR domain WD40 PF00400.32 RLN27348.1 - 4.2e-05 24.2 0.2 2.4 9.2 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.11 RLN27348.1 - 0.00053 19.9 0.0 0.0014 18.5 0.0 1.6 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A CDC45 PF02724.14 RLN27348.1 - 0.0084 14.5 6.4 0.012 14.0 6.4 1.2 1 0 0 1 1 1 1 CDC45-like protein Cwf_Cwc_15 PF04889.12 RLN27348.1 - 0.052 13.3 19.3 0.09 12.5 19.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Astro_capsid_p PF12226.8 RLN27348.1 - 2.2 7.3 13.4 3.7 6.6 13.4 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RNA_pol_3_Rpc31 PF11705.8 RLN27348.1 - 2.3 8.4 21.6 3.7 7.7 21.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Ras PF00071.22 RLN27349.1 - 8.5e-06 25.5 0.0 0.035 13.7 0.0 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 RLN27349.1 - 1.3e-05 25.4 0.0 0.00012 22.3 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN27349.1 - 0.0017 17.9 0.0 0.32 10.4 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family PduV-EutP PF10662.9 RLN27349.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 RLN27349.1 - 0.059 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 RLN27349.1 - 0.16 12.3 0.7 0.7 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain CAP_N PF01213.19 RLN27385.1 - 1.5e-59 202.0 2.3 7.7e-59 199.7 0.0 2.5 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 RLN27385.1 - 3e-54 182.9 0.9 4.1e-54 182.5 0.9 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 RLN27385.1 - 0.0014 18.4 1.2 0.0031 17.2 1.2 1.6 1 1 0 1 1 1 1 Tubulin binding cofactor C RNA_lig_T4_1 PF09511.10 RLN27385.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 RNA ligase DNMT1-RFD PF12047.8 RLN27386.1 - 0.082 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain CLAMP PF14769.6 RLN27387.1 - 2.5e-07 31.0 0.1 2.4e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 Flagellar C1a complex subunit C1a-32 ABC2_membrane PF01061.24 RLN27389.1 - 1.1e-30 106.6 26.3 1.1e-30 106.6 26.3 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RLN27389.1 - 5.9e-25 88.4 0.0 4.6e-15 56.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 RLN27389.1 - 9.5e-07 28.5 1.0 0.0066 16.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN27389.1 - 1.2e-06 28.5 0.1 0.0039 17.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 RLN27389.1 - 1.1e-05 25.7 0.0 0.22 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RLN27389.1 - 2.1e-05 25.1 0.6 0.064 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 RLN27389.1 - 3.3e-05 23.6 0.2 0.23 11.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 RLN27389.1 - 6.1e-05 23.1 0.1 0.36 10.9 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 RLN27389.1 - 9.2e-05 23.0 0.1 0.69 10.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 RLN27389.1 - 0.00071 20.0 0.0 0.92 9.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 RLN27389.1 - 0.0011 18.7 3.2 0.73 9.5 0.2 2.3 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 RLN27389.1 - 0.0026 17.8 1.0 0.28 11.2 0.2 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 RLN27389.1 - 0.0031 17.7 0.0 3.1 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain PDR_assoc PF08370.11 RLN27389.1 - 0.0056 16.4 0.9 0.021 14.6 0.9 1.9 1 0 0 1 1 1 1 Plant PDR ABC transporter associated AAA_28 PF13521.6 RLN27389.1 - 0.0062 16.8 0.6 0.63 10.3 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RLN27389.1 - 0.0093 16.4 0.5 1.5 9.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 RLN27389.1 - 0.013 14.8 2.0 1.9 7.7 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin Ploopntkinase3 PF18751.1 RLN27389.1 - 0.016 15.1 0.8 3 7.7 0.2 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_21 PF13304.6 RLN27389.1 - 0.023 14.5 0.2 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MeaB PF03308.16 RLN27389.1 - 0.03 13.3 0.7 3.8 6.4 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 RLN27389.1 - 0.032 14.6 0.2 7.9 6.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ABC_trans_N PF14510.6 RLN27389.1 - 0.07 13.8 0.3 0.22 12.2 0.0 1.9 2 0 0 2 2 1 0 ABC-transporter N-terminal PetG PF02529.15 RLN27389.1 - 0.078 12.8 4.1 0.052 13.4 1.2 2.2 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 NTPase_1 PF03266.15 RLN27389.1 - 0.083 12.8 1.3 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 RLN27389.1 - 0.1 12.5 4.1 3 7.7 0.7 2.5 2 0 0 2 2 2 0 NACHT domain DnaB_C PF03796.15 RLN27389.1 - 0.13 11.6 0.2 7.7 5.8 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain cobW PF02492.19 RLN27389.1 - 0.14 11.8 3.5 2.9 7.4 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 RLN27389.1 - 0.14 11.5 0.2 24 4.3 0.0 3.2 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 RLN27389.1 - 0.16 12.0 5.6 2.1 8.4 0.8 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_24 PF13479.6 RLN27389.1 - 0.18 11.5 3.0 7.9 6.1 0.3 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 RLN27389.1 - 0.22 11.9 0.7 4.6 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 RLN27389.1 - 0.26 11.6 3.4 3.3 8.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 RLN27389.1 - 0.27 11.3 0.4 26 4.8 0.0 2.3 2 0 0 2 2 2 0 Dynamin family RuvB_N PF05496.12 RLN27389.1 - 0.3 10.8 0.8 21 4.8 0.1 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain PduV-EutP PF10662.9 RLN27389.1 - 0.36 10.6 1.4 0.73 9.6 0.3 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC2_membrane_3 PF12698.7 RLN27389.1 - 1.6 7.8 21.7 3.3 6.7 21.7 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein Laminin_G_3 PF13385.6 RLN27390.1 - 8.3e-12 45.5 0.2 1.8e-11 44.4 0.2 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily F-box-like PF12937.7 RLN27390.1 - 0.088 12.7 0.1 0.29 11.1 0.1 1.9 1 0 0 1 1 1 0 F-box-like cNMP_binding PF00027.29 RLN27391.1 - 9.4e-35 118.6 0.4 5e-12 45.7 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN27391.1 - 1.6e-16 60.3 14.0 4.6e-10 39.1 4.6 2.2 2 0 0 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 RLN27391.1 - 2.4e-07 30.6 4.3 0.0024 17.8 0.5 2.9 2 0 0 2 2 2 2 Ion channel Ku PF02735.16 RLN27391.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Ku70/Ku80 beta-barrel domain Col_cuticle_N PF01484.17 RLN27391.1 - 0.045 13.8 0.0 0.35 11.0 0.0 2.4 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain TMEM192 PF14802.6 RLN27391.1 - 0.15 11.1 2.5 0.39 9.8 2.5 1.6 1 0 0 1 1 1 0 TMEM192 family TPR_1 PF00515.28 RLN27393.1 - 2.8e-06 26.9 0.1 8e-06 25.5 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 RLN27393.1 - 6.4e-06 25.9 0.9 1.4e-05 24.8 0.4 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN27393.1 - 0.00023 21.1 0.3 0.0011 19.1 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN27393.1 - 0.00029 20.4 0.1 0.00064 19.4 0.1 1.6 1 0 0 1 1 1 1 TPR repeat TPR_10 PF13374.6 RLN27393.1 - 0.00033 20.4 1.0 0.0015 18.3 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN27393.1 - 0.0017 18.6 1.1 0.0019 18.4 0.1 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN27393.1 - 0.0053 17.4 0.4 0.012 16.2 0.4 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN27393.1 - 0.016 15.2 1.1 0.027 14.5 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN27393.1 - 0.02 15.7 0.1 0.061 14.2 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.25 RLN27394.1 - 1.8e-25 89.8 0.0 2.4e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN27394.1 - 1.3e-12 47.6 0.0 1.8e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 RLN27394.1 - 0.021 15.5 0.3 0.021 15.5 0.3 2.5 2 2 0 2 2 2 0 Protein kinase C terminal domain ABC_membrane PF00664.23 RLN27395.1 - 3.1e-50 171.4 15.9 4.1e-50 171.0 15.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN27395.1 - 2.8e-46 157.5 0.0 1.8e-32 112.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN27395.1 - 1.2e-09 38.0 2.9 0.00028 20.4 0.0 3.2 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 RLN27395.1 - 8.2e-05 21.6 0.4 0.045 12.6 0.1 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA PF00004.29 RLN27395.1 - 0.0009 19.7 1.6 2.2 8.7 0.2 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN27395.1 - 0.00093 19.5 0.6 0.071 13.4 0.2 3.1 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 RLN27395.1 - 0.0014 18.5 1.6 0.54 10.0 0.1 3.0 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 RLN27395.1 - 0.0016 18.6 5.6 2 8.7 0.3 4.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 RLN27395.1 - 0.002 18.6 1.5 0.0037 17.7 0.5 1.9 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 RLN27395.1 - 0.0025 17.1 0.0 0.0054 16.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 RLN27395.1 - 0.0051 16.5 0.1 0.015 15.1 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF87 PF01935.17 RLN27395.1 - 0.019 15.0 0.0 0.06 13.4 0.0 1.8 1 0 0 1 1 1 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 RLN27395.1 - 0.048 13.6 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 RLN27395.1 - 0.062 13.0 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain MtrB PF05440.12 RLN27395.1 - 0.069 13.6 1.8 30 5.1 0.4 4.2 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B AAA_25 PF13481.6 RLN27395.1 - 0.071 12.7 0.3 0.77 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP-synt_C PF00137.21 RLN27395.1 - 5.8 7.3 8.1 16 5.9 0.0 3.8 3 0 0 3 3 3 0 ATP synthase subunit C UreD PF01774.17 RLN27396.1 - 2.5e-48 164.8 0.1 2.9e-48 164.6 0.1 1.0 1 0 0 1 1 1 1 UreD urease accessory protein DUF5329 PF17263.2 RLN27396.1 - 0.071 13.3 0.0 0.35 11.1 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5329) FYVE PF01363.21 RLN27403.1 - 2.3e-05 24.4 15.9 5e-05 23.4 15.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 RLN27403.1 - 0.0083 16.8 0.1 0.026 15.2 0.1 1.9 1 0 0 1 1 1 1 GAF domain FYVE_2 PF02318.16 RLN27403.1 - 0.56 10.4 10.7 0.19 12.0 7.4 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger RRM_1 PF00076.22 RLN27406.1 - 5.6e-19 67.7 0.1 2.1e-06 27.4 0.0 4.5 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN27406.1 - 5.5e-05 23.2 0.0 0.48 10.6 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif SURNod19 PF07712.12 RLN27407.1 - 2.7e-47 161.3 9.3 3.7e-45 154.3 9.3 3.3 1 1 0 1 1 1 1 Stress up-regulated Nod 19 ABC2_membrane PF01061.24 RLN27408.1 - 9.9e-24 83.9 30.2 1.5e-23 83.3 30.2 1.3 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN27408.1 - 0.002 18.0 0.0 0.002 18.0 0.0 2.9 3 0 0 3 3 3 1 CDR ABC transporter TBCC PF07986.12 RLN27409.1 - 1.3e-06 28.1 0.1 3.8e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Tubulin binding cofactor C DUF2614 PF11023.8 RLN27409.1 - 0.1 12.7 2.9 0.26 11.4 2.9 1.6 1 0 0 1 1 1 0 Zinc-ribbon containing domain NMD3 PF04981.13 RLN27409.1 - 0.38 10.2 1.1 0.54 9.7 0.0 1.8 3 0 0 3 3 3 0 NMD3 family UQ_con PF00179.26 RLN27424.1 - 5.2e-14 52.1 0.8 4.8e-09 36.0 0.2 2.0 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme DinB_2 PF12867.7 RLN27424.1 - 0.0055 17.2 0.2 0.011 16.2 0.1 1.6 1 1 1 2 2 2 1 DinB superfamily RWD PF05773.22 RLN27424.1 - 0.11 12.7 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 RWD domain LRR_9 PF14580.6 RLN27425.1 - 1.6e-10 40.8 0.0 5.6e-10 39.0 0.0 2.0 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 RLN27425.1 - 0.0091 15.7 2.7 0.13 12.0 2.7 2.5 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 RLN27425.1 - 0.14 12.6 3.4 4.6 7.8 0.1 3.1 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) BK_channel_a PF03493.18 RLN27426.1 - 1.1e-24 86.4 0.0 2.9e-24 85.1 0.0 1.7 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 RLN27426.1 - 2.4e-13 49.8 12.7 1.6e-12 47.2 12.5 2.3 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.31 RLN27426.1 - 2.4e-06 27.0 7.1 4.7e-06 26.0 7.1 1.5 1 0 0 1 1 1 1 Ion transport protein Castor_Poll_mid PF06241.12 RLN27426.1 - 6.1e-05 22.9 0.0 0.15 12.0 0.0 3.7 4 0 0 4 4 4 2 Castor and Pollux, part of voltage-gated ion channel TrkA_N PF02254.18 RLN27426.1 - 0.00054 20.2 0.0 0.074 13.3 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain PseudoU_synth_1 PF01416.20 RLN27427.1 - 3.6e-14 53.1 0.0 6.3e-09 36.3 0.0 2.3 1 1 1 2 2 2 2 tRNA pseudouridine synthase Sec8_exocyst PF04048.14 RLN27428.1 - 2.1e-11 43.9 2.5 4.7e-11 42.8 1.2 2.3 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 RLN27428.1 - 7.3e-08 32.0 4.7 1.4e-07 31.1 4.7 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Vps53_N PF04100.12 RLN27428.1 - 0.0016 17.5 6.3 0.0027 16.7 6.3 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal Tweety PF04906.13 RLN27428.1 - 0.019 13.6 0.6 0.053 12.2 0.4 1.8 1 1 0 1 1 1 0 Tweety THOC7 PF05615.13 RLN27428.1 - 0.066 13.5 1.0 5.9 7.2 2.3 2.8 2 0 0 2 2 2 0 Tho complex subunit 7 La PF05383.17 RLN27442.1 - 2.5e-15 56.2 0.4 4.2e-15 55.5 0.4 1.3 1 0 0 1 1 1 1 La domain Polyketide_cyc PF03364.20 RLN27442.1 - 0.0025 18.0 0.1 0.0055 16.9 0.1 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Podoplanin PF05808.11 RLN27443.1 - 9.7e-05 22.5 0.1 0.00017 21.7 0.1 1.4 1 0 0 1 1 1 1 Podoplanin Adeno_E3_CR2 PF02439.15 RLN27443.1 - 0.0014 18.3 1.5 0.0028 17.4 1.5 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Mid2 PF04478.12 RLN27443.1 - 0.0064 16.3 0.1 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Syndecan PF01034.20 RLN27443.1 - 0.011 15.6 0.6 0.023 14.6 0.6 1.5 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 RLN27443.1 - 0.013 16.4 1.1 0.042 14.7 0.1 2.3 3 0 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 RLN27443.1 - 0.013 15.5 0.1 0.032 14.2 0.0 1.7 2 0 0 2 2 2 0 Protocadherin FixQ PF05545.11 RLN27443.1 - 0.033 14.2 0.1 0.08 12.9 0.1 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ PepSY_TM PF03929.16 RLN27443.1 - 0.037 13.7 0.1 0.07 12.8 0.1 1.4 1 0 0 1 1 1 0 PepSY-associated TM region PTP_tm PF18861.1 RLN27443.1 - 0.042 13.8 0.6 0.094 12.7 0.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J TMEM154 PF15102.6 RLN27443.1 - 0.042 13.7 0.2 0.079 12.9 0.0 1.6 2 0 0 2 2 2 0 TMEM154 protein family Amnionless PF14828.6 RLN27443.1 - 0.073 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Amnionless MtrF PF09472.10 RLN27443.1 - 0.26 10.7 4.9 0.5 9.8 4.9 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Pkinase PF00069.25 RLN27444.1 - 3.1e-47 161.2 0.0 4.7e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN27444.1 - 1.4e-42 145.8 0.0 2.1e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Podoplanin PF05808.11 RLN27444.1 - 2.1e-09 37.7 0.9 0.0029 17.8 0.0 2.7 2 1 0 2 2 2 2 Podoplanin EphA2_TM PF14575.6 RLN27444.1 - 1.9e-07 31.9 0.5 0.0015 19.4 0.1 2.6 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 RLN27444.1 - 2.2e-07 30.5 4.8 0.0012 18.5 2.2 2.5 2 0 0 2 2 2 2 Adenovirus E3 region protein CR2 Shisa PF13908.6 RLN27444.1 - 1.1e-06 29.0 0.1 0.00067 19.9 0.1 2.5 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Amnionless PF14828.6 RLN27444.1 - 2.6e-06 26.6 0.0 0.0024 16.8 0.0 2.2 2 0 0 2 2 2 2 Amnionless TMEM154 PF15102.6 RLN27444.1 - 3.7e-05 23.7 0.0 0.012 15.5 0.0 2.6 2 0 0 2 2 2 1 TMEM154 protein family Protocadherin PF08374.11 RLN27444.1 - 0.00012 22.1 0.1 0.031 14.2 0.0 2.2 2 0 0 2 2 2 1 Protocadherin PTP_tm PF18861.1 RLN27444.1 - 0.00022 21.3 4.0 0.0086 16.1 0.4 2.4 2 0 0 2 2 2 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J CD34_antigen PF06365.12 RLN27444.1 - 0.00024 20.7 0.0 0.062 12.9 0.0 2.3 2 0 0 2 2 2 1 CD34/Podocalyxin family CYYR1 PF10873.8 RLN27444.1 - 0.00036 21.0 0.9 0.042 14.3 0.1 2.8 2 0 0 2 2 2 1 Cysteine and tyrosine-rich protein 1 PepSY_TM PF03929.16 RLN27444.1 - 0.00043 20.1 0.2 0.086 12.5 0.1 2.4 2 0 0 2 2 2 1 PepSY-associated TM region DAP10 PF07213.11 RLN27444.1 - 0.00086 19.2 4.4 0.21 11.6 0.2 3.4 3 0 0 3 3 3 1 DAP10 membrane protein DUF5518 PF17647.1 RLN27444.1 - 0.0015 18.7 7.5 0.37 11.0 2.0 2.5 2 0 0 2 2 2 2 Family of unknown function (DUF5518) SIT PF15330.6 RLN27444.1 - 0.0025 18.3 0.1 2 8.9 0.1 2.5 2 0 0 2 2 2 1 SHP2-interacting transmembrane adaptor protein, SIT DUF4381 PF14316.6 RLN27444.1 - 0.0026 18.0 0.1 1.3 9.2 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) TMEM100 PF16311.5 RLN27444.1 - 0.0036 16.9 0.3 2.2 7.9 0.0 2.5 2 0 0 2 2 2 1 Transmembrane protein 100 Glycophorin_A PF01102.18 RLN27444.1 - 0.0038 17.4 0.0 0.048 13.9 0.0 2.4 2 0 0 2 2 2 1 Glycophorin A Mid2 PF04478.12 RLN27444.1 - 0.0061 16.4 0.2 1.7 8.5 0.1 2.4 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor ECSCR PF15820.5 RLN27444.1 - 0.0063 16.3 0.1 0.48 10.3 0.1 2.5 2 0 0 2 2 2 1 Endothelial cell-specific chemotaxis regulator MAP17 PF15807.5 RLN27444.1 - 0.0065 16.7 0.0 0.25 11.6 0.0 2.2 2 0 0 2 2 2 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF2681 PF10883.8 RLN27444.1 - 0.012 16.1 0.1 6.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Phage_holin_2_4 PF16082.5 RLN27444.1 - 0.013 15.2 0.6 2.6 7.9 0.1 2.5 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like TMEM51 PF15345.6 RLN27444.1 - 0.017 15.0 0.0 2.8 7.7 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 TraL PF07178.11 RLN27444.1 - 0.017 15.5 0.7 2.5 8.6 0.0 2.6 2 0 0 2 2 2 0 TraL protein DUF456 PF04306.13 RLN27444.1 - 0.02 15.2 6.5 1.1 9.6 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF456) S1FA PF04689.13 RLN27444.1 - 0.022 14.9 1.0 4.4 7.5 0.1 2.8 3 0 0 3 3 2 0 DNA binding protein S1FA DUF4330 PF14221.6 RLN27444.1 - 0.023 14.9 1.2 1.8 8.7 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) Syndecan PF01034.20 RLN27444.1 - 0.027 14.4 9.1 0.054 13.4 2.8 2.5 2 0 0 2 2 2 0 Syndecan domain YajC PF02699.15 RLN27444.1 - 0.034 14.0 0.8 0.21 11.5 0.3 2.2 2 0 0 2 2 2 0 Preprotein translocase subunit stn_TNFRSF12A PF12191.8 RLN27444.1 - 0.061 13.5 0.1 8.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF4051 PF13260.6 RLN27444.1 - 0.22 11.3 5.6 0.27 11.0 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) DUF347 PF03988.12 RLN27444.1 - 0.43 10.8 5.4 7.3 6.9 0.3 2.6 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Vpu PF00558.19 RLN27444.1 - 0.77 9.6 2.0 19 5.1 0.2 2.3 2 0 0 2 2 2 0 Vpu protein ABC_membrane PF00664.23 RLN27445.1 - 5.2e-30 105.0 8.0 7e-30 104.6 8.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN27445.1 - 1.2e-17 64.7 0.0 2.6e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN27445.1 - 0.0069 15.8 0.1 1.6 8.1 0.1 2.3 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RLN27445.1 - 0.028 14.8 0.0 0.071 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 RLN27445.1 - 0.034 14.4 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 RLN27446.1 - 1.5e-47 162.2 0.0 2.4e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN27446.1 - 4.3e-42 144.2 0.0 6.9e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Shisa PF13908.6 RLN27446.1 - 6.7e-05 23.2 0.5 0.00015 22.1 0.5 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Amnionless PF14828.6 RLN27446.1 - 0.00033 19.6 0.1 0.00047 19.1 0.1 1.1 1 0 0 1 1 1 1 Amnionless EphA2_TM PF14575.6 RLN27446.1 - 0.00042 21.1 0.1 0.001 19.9 0.1 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 RLN27446.1 - 0.00095 19.1 0.0 0.003 17.5 0.0 1.8 1 1 1 2 2 2 1 TMEM154 protein family Adeno_E3_CR2 PF02439.15 RLN27446.1 - 0.0011 18.7 2.1 0.0022 17.7 2.1 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 RLN27446.1 - 0.0012 18.9 1.6 0.0019 18.3 0.5 1.8 1 1 0 1 1 1 1 Podoplanin Protocadherin PF08374.11 RLN27446.1 - 0.0016 18.5 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 Protocadherin DAP10 PF07213.11 RLN27446.1 - 0.0063 16.4 0.3 0.024 14.6 0.3 2.0 1 0 0 1 1 1 1 DAP10 membrane protein CYYR1 PF10873.8 RLN27446.1 - 0.0075 16.7 0.1 0.021 15.3 0.1 1.7 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 Glycophorin_A PF01102.18 RLN27446.1 - 0.013 15.7 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 Glycophorin A Syndecan PF01034.20 RLN27446.1 - 0.023 14.6 2.1 0.05 13.5 2.1 1.5 1 0 0 1 1 1 0 Syndecan domain RIFIN PF02009.16 RLN27446.1 - 0.032 14.1 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Rifin CD34_antigen PF06365.12 RLN27446.1 - 0.034 13.7 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF4051 PF13260.6 RLN27446.1 - 0.052 13.3 1.3 0.097 12.4 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) YajC PF02699.15 RLN27446.1 - 0.071 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit Orf78 PF06024.12 RLN27446.1 - 0.084 13.2 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Rax2 PF12768.7 RLN27446.1 - 0.1 12.1 0.0 0.42 10.0 0.0 2.1 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Man-6-P_recep PF02157.15 RLN27446.1 - 0.13 11.4 0.1 0.22 10.6 0.1 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate receptor 2-Hacid_dh_C PF02826.19 RLN27448.1 - 7.6e-56 188.3 0.0 1e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 RLN27448.1 - 7.3e-28 96.9 0.0 9.9e-28 96.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 RLN27448.1 - 0.057 14.0 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF4440 PF14534.6 RLN27448.1 - 0.095 13.1 0.0 0.56 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) Dioxygenase_C PF00775.21 RLN27449.1 - 2.4e-09 36.9 0.1 4.5e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase TRAF_BIRC3_bd PF16673.5 RLN27449.1 - 0.047 13.5 0.5 0.1 12.4 0.5 1.5 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Dioxygenase_C PF00775.21 RLN27450.1 - 2.4e-09 36.9 0.1 4.6e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase TRAF_BIRC3_bd PF16673.5 RLN27450.1 - 0.1 12.4 0.5 0.1 12.4 0.5 1.6 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain 2-Hacid_dh_C PF02826.19 RLN27451.1 - 7.6e-56 188.3 0.0 1e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 RLN27451.1 - 7.3e-28 96.9 0.0 9.9e-28 96.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 RLN27451.1 - 0.057 14.0 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF4440 PF14534.6 RLN27451.1 - 0.095 13.1 0.0 0.56 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) DUF747 PF05346.11 RLN27462.1 - 7.2e-96 321.4 20.8 8.8e-96 321.1 20.8 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family PUF PF00806.19 RLN27463.1 - 1.9e-47 156.3 6.6 4.6e-06 26.0 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat zf-CCCH_4 PF18044.1 RLN27463.1 - 5e-07 29.4 4.7 1.8e-06 27.6 4.7 2.0 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 RLN27463.1 - 0.00023 21.1 6.5 0.00046 20.1 6.5 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 RLN27463.1 - 0.00083 19.2 4.5 0.0018 18.2 4.5 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 RLN27463.1 - 0.0026 18.5 1.3 0.0066 17.1 1.3 1.7 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 RLN27463.1 - 0.11 13.1 4.9 0.22 12.1 4.9 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF3395 PF11875.8 RLN27464.1 - 1.7e-40 138.4 0.1 2.7e-40 137.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 RLN27464.1 - 3.3e-14 52.7 0.1 5.9e-14 51.9 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain MORN PF02493.20 RLN27465.1 - 9.8e-40 132.1 60.9 1.6e-06 27.6 0.4 10.5 10 0 0 10 10 10 10 MORN repeat HSDR_N_2 PF13588.6 RLN31269.1 - 0.0032 17.5 0.1 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) Pkip-1 PF06878.11 RLN31269.1 - 0.015 15.4 0.3 0.03 14.4 0.3 1.5 1 0 0 1 1 1 0 Pkip-1 protein TnpB_IS66 PF05717.13 RLN31270.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 IS66 Orf2 like protein ABC2_membrane PF01061.24 RLN31271.1 - 3.7e-19 69.0 14.1 4.1e-19 68.8 14.1 1.0 1 0 0 1 1 1 1 ABC-2 type transporter DUF588 PF04535.12 RLN31271.1 - 0.094 12.5 3.2 0.082 12.7 2.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF588) DUF1772 PF08592.11 RLN31271.1 - 1.5 9.1 10.1 7.3 6.9 10.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Mannosyl_trans3 PF11051.8 RLN31275.1 - 8.2e-32 110.7 0.0 2.4e-30 105.8 0.0 2.2 1 1 0 1 1 1 1 Mannosyltransferase putative Couple_hipA PF13657.6 RLN31275.1 - 0.05 14.2 0.2 3.8 8.2 0.0 2.6 2 1 0 2 2 2 0 HipA N-terminal domain DUF4436 PF14494.6 RLN31276.1 - 0.0038 16.6 3.9 0.84 8.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4436) DUF2347 PF09804.9 RLN31276.1 - 0.031 13.9 0.2 3.2 7.3 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) FA_hydroxylase PF04116.13 RLN31276.1 - 0.069 13.5 14.8 0.25 11.7 0.5 4.2 4 0 0 4 4 4 0 Fatty acid hydroxylase superfamily UPF0114 PF03350.16 RLN31276.1 - 3.6 7.8 8.6 7.2 6.8 0.9 3.0 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 FAD_binding_7 PF03441.14 RLN31277.1 - 1.2e-67 227.3 0.5 1.8e-67 226.8 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 RLN31277.1 - 3.9e-32 111.5 0.1 6.6e-32 110.8 0.1 1.3 1 0 0 1 1 1 1 DNA photolyase Ank_2 PF12796.7 RLN31278.1 - 1.7e-42 143.9 12.4 2e-16 60.3 0.9 6.2 3 1 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN31278.1 - 5.6e-25 87.1 11.0 8.7e-08 32.3 0.8 8.4 5 2 3 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN31278.1 - 4.9e-21 72.6 10.0 0.0042 17.5 0.1 9.8 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.6 RLN31278.1 - 7.2e-21 74.3 12.1 1.9e-07 31.5 0.0 7.0 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 RLN31278.1 - 3.1e-19 68.5 13.8 2.9e-06 27.5 0.2 8.5 9 0 0 9 9 9 4 Ankyrin repeat Ank_2 PF12796.7 RLN31279.1 - 5.3e-18 65.4 0.2 0.00072 20.1 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN31279.1 - 3.5e-14 51.5 0.1 0.00056 20.2 0.0 6.8 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 RLN31279.1 - 4e-13 49.2 0.1 0.00028 21.2 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 RLN31279.1 - 1.1e-12 47.9 0.3 3e-05 24.2 0.1 5.3 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN31279.1 - 1.3e-09 38.3 0.4 7.7e-05 23.2 0.1 5.0 5 1 1 6 6 6 2 Ankyrin repeats (many copies) BPL_LplA_LipB_2 PF16917.5 RLN31279.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family DUF2451 PF10474.9 RLN31279.1 - 0.094 12.5 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Ank_2 PF12796.7 RLN31280.1 - 1e-17 64.5 3.8 8.3e-11 42.3 0.4 4.9 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN31280.1 - 5.2e-12 45.8 0.1 0.00084 19.6 0.3 5.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN31280.1 - 6e-11 42.6 0.1 0.0019 18.7 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN31280.1 - 1.3e-10 40.5 0.4 0.08 13.5 0.0 6.9 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 RLN31280.1 - 3.8e-09 36.6 0.0 0.12 12.8 0.0 5.2 4 1 1 5 5 5 2 Ankyrin repeat Haem_oxygenas_2 PF14518.6 RLN31280.1 - 0.069 12.9 2.8 4.7 6.9 0.2 3.0 2 1 1 3 3 3 0 Iron-containing redox enzyme DUF2451 PF10474.9 RLN31280.1 - 0.1 12.3 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) p450 PF00067.22 RLN31281.1 - 8.4e-36 123.7 0.0 9.1e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC_tran PF00005.27 RLN31282.1 - 7.7e-43 146.3 0.9 1.1e-19 71.2 0.0 3.8 3 1 0 4 4 3 3 ABC transporter AAA_21 PF13304.6 RLN31282.1 - 2.2e-18 67.1 4.9 0.00072 19.4 0.0 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RLN31282.1 - 8.3e-10 38.5 0.0 0.0068 15.9 0.0 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain NACHT PF05729.12 RLN31282.1 - 5e-08 33.0 0.1 0.0013 18.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 RLN31282.1 - 2e-07 31.5 4.6 0.0052 17.2 0.0 3.1 3 1 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 RLN31282.1 - 5.1e-07 29.3 0.2 0.033 13.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN31282.1 - 5.2e-07 30.4 9.0 0.0047 17.4 0.9 3.5 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.6 RLN31282.1 - 1.4e-06 28.6 0.4 0.074 13.3 0.0 3.4 2 1 1 3 3 3 2 AAA domain AAA_14 PF13173.6 RLN31282.1 - 8.1e-06 25.9 0.1 0.15 12.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 RLN31282.1 - 4.2e-05 23.5 0.1 0.37 10.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 RLN31282.1 - 5.1e-05 23.6 1.8 0.1 12.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 RLN31282.1 - 5.1e-05 23.1 4.3 0.25 11.0 0.0 3.7 4 0 0 4 4 4 2 AAA ATPase domain RNA_helicase PF00910.22 RLN31282.1 - 7.2e-05 23.1 0.0 0.45 10.9 0.0 2.7 2 0 0 2 2 2 2 RNA helicase ABC_tran_Xtn PF12848.7 RLN31282.1 - 8e-05 22.6 9.8 8e-05 22.6 9.8 2.0 2 0 0 2 2 1 1 ABC transporter IstB_IS21 PF01695.17 RLN31282.1 - 8.1e-05 22.4 0.1 0.42 10.3 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein MMR_HSR1 PF01926.23 RLN31282.1 - 0.00016 21.8 0.3 0.71 10.0 0.1 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 RLN31282.1 - 0.00019 22.0 0.1 0.15 12.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RLN31282.1 - 0.00029 21.2 0.0 0.91 10.0 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 RLN31282.1 - 0.00041 20.4 0.3 0.11 12.5 0.1 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 RLN31282.1 - 0.00041 20.0 0.1 0.14 11.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 RLN31282.1 - 0.00041 20.1 1.9 0.3 10.8 0.1 2.8 3 0 0 3 3 2 2 AAA domain ATP-synt_ab PF00006.25 RLN31282.1 - 0.0016 18.2 0.0 0.31 10.7 0.0 2.6 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.6 RLN31282.1 - 0.0019 18.4 1.8 2.2 8.5 0.1 3.6 3 1 0 3 3 3 1 AAA domain AAA_7 PF12775.7 RLN31282.1 - 0.0021 17.6 0.1 1.1 8.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase_2 PF01637.18 RLN31282.1 - 0.0027 17.6 0.4 2 8.3 0.0 2.8 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 RLN31282.1 - 0.0035 17.1 0.2 0.37 10.5 0.1 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 RLN31282.1 - 0.0058 16.6 0.7 4.7 7.1 0.1 3.0 3 0 0 3 3 2 0 NTPase AAA_30 PF13604.6 RLN31282.1 - 0.0074 16.0 6.5 0.11 12.1 0.1 3.7 3 2 1 4 4 4 1 AAA domain Roc PF08477.13 RLN31282.1 - 0.0082 16.3 1.4 2 8.6 0.0 2.9 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 RLN31282.1 - 0.012 15.6 4.9 3.2 7.7 0.2 3.6 3 1 0 3 3 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 RLN31282.1 - 0.019 14.2 1.4 5 6.2 0.1 2.7 3 0 0 3 3 2 0 NB-ARC domain SRP54 PF00448.22 RLN31282.1 - 0.023 14.4 0.4 6.5 6.3 0.1 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Bac_DnaA PF00308.18 RLN31282.1 - 0.023 14.5 0.0 7.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Bacterial dnaA protein Rad17 PF03215.15 RLN31282.1 - 0.025 14.5 0.9 11 5.9 0.0 3.0 3 0 0 3 3 2 0 Rad17 P-loop domain RuvB_N PF05496.12 RLN31282.1 - 0.065 13.0 0.9 3 7.6 0.0 2.8 3 0 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain ABC_ATPase PF09818.9 RLN31282.1 - 0.07 11.9 1.3 2.9 6.6 0.1 2.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class cobW PF02492.19 RLN31282.1 - 0.13 11.8 1.1 6.5 6.3 0.2 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain dNK PF01712.19 RLN31282.1 - 0.2 11.5 0.6 2.3 8.0 0.0 2.5 3 0 0 3 3 2 0 Deoxynucleoside kinase AAA_27 PF13514.6 RLN31282.1 - 0.43 10.1 8.2 1.7 8.2 0.0 3.1 4 0 0 4 4 3 0 AAA domain DUF87 PF01935.17 RLN31282.1 - 1.7 8.7 6.6 4.4 7.3 0.1 3.4 3 1 1 4 4 3 0 Helicase HerA, central domain Thymidylate_kin PF02223.17 RLN31282.1 - 4.5 6.9 6.1 7.7 6.1 0.0 3.2 3 0 0 3 3 3 0 Thymidylate kinase MeaB PF03308.16 RLN31282.1 - 9 5.2 8.4 0.89 8.5 0.0 3.0 4 0 0 4 4 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynein_light PF01221.18 RLN31283.1 - 2.6e-23 82.2 0.0 6.2e-14 52.1 0.1 2.4 2 1 0 2 2 2 2 Dynein light chain type 1 Tim17 PF02466.19 RLN31284.1 - 4e-19 69.0 0.5 5.6e-19 68.6 0.5 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Anoctamin PF04547.12 RLN31285.1 - 2.7e-10 39.7 0.5 3.6e-10 39.3 0.5 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel TMC PF07810.13 RLN31285.1 - 0.00043 20.8 0.2 0.00043 20.8 0.2 3.0 4 0 0 4 4 4 1 TMC domain Glyco_hydro_1 PF00232.18 RLN31286.1 - 1.5e-117 392.8 0.2 1.8e-117 392.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 RLN31286.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) zf-C4H2 PF10146.9 RLN31288.1 - 0.0054 17.1 9.7 0.068 13.5 0.8 2.4 2 0 0 2 2 2 2 Zinc finger-containing protein Fmp27_WPPW PF10359.9 RLN31288.1 - 0.028 13.3 2.2 1.9 7.2 0.2 2.2 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Filament PF00038.21 RLN31288.1 - 0.32 10.5 14.3 1.4 8.5 5.3 2.4 2 0 0 2 2 2 0 Intermediate filament protein DUF4407 PF14362.6 RLN31288.1 - 1.6 8.0 9.2 1.5 8.1 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FapA PF03961.13 RLN31288.1 - 2.1 6.8 7.4 1.2 7.7 0.7 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF489 PF04356.12 RLN31288.1 - 2.2 8.2 7.2 2.4 8.1 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF489) Exonuc_VII_L PF02601.15 RLN31288.1 - 3.1 7.3 10.4 6.1 6.3 0.5 2.7 3 0 0 3 3 3 0 Exonuclease VII, large subunit DUF1664 PF07889.12 RLN31288.1 - 5.2 7.1 12.9 5.8 7.0 1.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) FemAB PF02388.16 RLN31288.1 - 5.3 5.8 10.4 0.092 11.6 2.2 1.9 2 0 0 2 2 2 0 FemAB family TMF_DNA_bd PF12329.8 RLN31288.1 - 7.5 6.6 13.4 12 5.9 1.5 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CREPT PF16566.5 RLN31288.1 - 7.9 6.6 15.1 0.25 11.5 3.4 2.5 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour ubiquitin PF00240.23 RLN31289.1 - 6.9e-16 57.8 0.0 2.6e-15 55.9 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.6 RLN31289.1 - 0.002 18.5 0.0 0.0039 17.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Tudor-knot PF11717.8 RLN31289.1 - 0.0033 17.3 0.6 0.0075 16.1 0.6 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MBT PF02820.18 RLN31289.1 - 0.01 16.2 0.2 0.022 15.1 0.2 1.5 1 0 0 1 1 1 0 mbt repeat Rad60-SLD_2 PF13881.6 RLN31289.1 - 0.18 11.9 0.0 0.49 10.5 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Cytochrom_B561 PF03188.16 RLN31290.1 - 2.9e-10 40.4 2.5 1.3e-09 38.3 2.6 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Cytochrom_B561 PF03188.16 RLN31291.1 - 5e-14 52.6 4.8 8.5e-14 51.9 4.8 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Porin_3 PF01459.22 RLN31291.1 - 0.057 12.9 0.2 0.14 11.6 0.1 1.6 2 0 0 2 2 2 0 Eukaryotic porin Prenyltrans PF00432.21 RLN31292.1 - 1.9e-54 181.1 13.7 7.6e-14 51.2 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 RLN31292.1 - 1.8e-05 24.0 0.0 0.0027 16.9 0.0 2.9 1 1 3 4 4 4 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 RLN31292.1 - 7.2e-05 22.0 0.0 0.0081 15.3 0.0 2.9 2 1 1 3 3 3 1 Squalene-hopene cyclase C-terminal domain Proteasome PF00227.26 RLN31294.1 - 7.2e-13 48.4 1.3 3.8e-10 39.6 0.5 2.2 1 1 1 2 2 2 2 Proteasome subunit GP120 PF00516.18 RLN31294.1 - 0.22 10.1 3.5 0.72 8.4 3.5 1.7 1 1 0 1 1 1 0 Envelope glycoprotein GP120 Arm PF00514.23 RLN31335.1 - 1e-48 161.9 15.0 2.1e-05 24.4 0.0 9.5 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN31335.1 - 1.2e-17 64.0 36.4 0.0014 19.1 1.2 5.7 5 0 0 5 5 5 5 HEAT-like repeat HEAT_2 PF13646.6 RLN31335.1 - 1.3e-16 60.8 45.4 0.00034 20.9 7.0 5.6 3 2 2 5 5 5 4 HEAT repeats HEAT PF02985.22 RLN31335.1 - 5.9e-14 51.0 21.8 2.1 8.8 0.0 10.1 10 0 0 10 10 10 2 HEAT repeat HEAT_PBS PF03130.16 RLN31335.1 - 4.3e-06 26.9 52.8 9.1 7.3 0.1 10.5 10 0 0 10 10 10 5 PBS lyase HEAT-like repeat DUF3247 PF11607.8 RLN31335.1 - 0.01 16.1 4.7 42 4.5 0.0 5.2 1 1 3 5 5 5 0 Protein of unknown function (DUF3247) DUF1593 PF07632.11 RLN31335.1 - 0.014 14.8 1.4 49 3.2 0.0 4.3 2 1 3 5 5 5 0 Protein of unknown function (DUF1593) GH97_C PF14509.6 RLN31335.1 - 0.046 13.9 7.0 2.8e+02 1.8 0.0 6.5 2 1 5 7 7 7 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation Adaptin_N PF01602.20 RLN31335.1 - 0.19 10.3 0.0 2 6.9 0.0 2.6 2 1 2 4 4 4 0 Adaptin N terminal region Sds3 PF08598.11 RLN31335.1 - 0.34 10.9 1.2 32 4.4 1.2 3.3 1 1 0 1 1 1 0 Sds3-like baeRF_family10 PF18854.1 RLN31335.1 - 2.8 8.2 32.3 3.6 7.8 1.5 7.9 4 4 3 9 9 9 0 Bacterial archaeo-eukaryotic release factor family 10 Aldo_ket_red PF00248.21 RLN31353.1 - 2.6e-10 40.0 0.1 2.9e-10 39.8 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Nyv1_N PF09426.10 RLN31354.1 - 0.069 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Vacuolar R-SNARE Nyv1 N terminal Alpha_adaptinC2 PF02883.20 RLN31355.1 - 1.9e-15 57.1 0.0 3.3e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain Alpha_adaptin_C PF02296.16 RLN31355.1 - 1.3e-13 51.1 0.0 2.9e-13 50.0 0.0 1.6 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain HCV_NS5a_1b PF08301.13 RLN31355.1 - 0.071 13.7 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a domain 1b Ribosomal_L28 PF00830.19 RLN31356.1 - 1.7e-18 66.5 0.8 2.7e-18 65.9 0.8 1.3 1 0 0 1 1 1 1 Ribosomal L28 family Peptidase_M42 PF05343.14 RLN31356.1 - 0.019 14.0 0.0 0.021 13.8 0.0 1.1 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase DUF1206 PF06724.11 RLN31357.1 - 0.0016 18.5 0.3 0.0016 18.5 0.3 3.8 5 0 0 5 5 5 1 Domain of Unknown Function (DUF1206) DUF543 PF04418.12 RLN31357.1 - 0.95 9.5 3.5 1.3 9.1 1.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF543) Tyrosinase PF00264.20 RLN31358.1 - 2.2e-48 165.5 0.1 3.3e-24 86.4 0.0 2.7 2 0 0 2 2 2 2 Common central domain of tyrosinase Pertussis_S2S3 PF02918.15 RLN31358.1 - 0.01 15.8 0.0 1.9 8.4 0.0 2.8 3 0 0 3 3 3 0 Pertussis toxin, subunit 2 and 3, C-terminal domain Lectin_C PF00059.21 RLN31358.1 - 0.024 15.4 0.1 2.8 8.7 0.0 3.1 2 0 0 2 2 2 0 Lectin C-type domain TraW_N PF12477.8 RLN31358.1 - 0.18 11.8 1.0 45 4.2 0.0 3.4 3 0 0 3 3 3 0 Sex factor F TraW protein N terminal Nepo_coat PF03391.15 RLN31358.1 - 1 8.8 4.9 1.8 8.0 0.3 2.6 2 0 0 2 2 2 0 Nepovirus coat protein, central domain DUF4329 PF14220.6 RLN31358.1 - 1.9 8.5 4.9 25 4.9 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4329) FMN_dh PF01070.18 RLN31360.1 - 3.9e-30 105.1 0.1 4.3e-30 104.9 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase FMN_dh PF01070.18 RLN31361.1 - 9.6e-149 495.1 11.0 6.4e-57 193.2 0.1 4.0 4 0 0 4 4 4 4 FMN-dependent dehydrogenase ThiG PF05690.14 RLN31361.1 - 1.5e-08 34.2 0.4 0.0029 16.9 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.17 RLN31361.1 - 0.00014 21.3 0.0 0.7 9.2 0.0 2.7 2 0 0 2 2 2 2 Thiamine monophosphate synthase Dus PF01207.17 RLN31361.1 - 0.00095 18.3 0.0 2.6 7.1 0.0 3.0 3 0 0 3 3 3 2 Dihydrouridine synthase (Dus) Patatin PF01734.22 RLN31361.1 - 0.0036 17.5 0.1 1.7 8.8 0.0 2.4 2 0 0 2 2 2 2 Patatin-like phospholipase GST_C_2 PF13410.6 RLN31361.1 - 0.01 15.8 0.0 1.8 8.7 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain zf-met2 PF12907.7 RLN31362.1 - 0.039 14.1 4.8 0.57 10.4 4.8 2.5 1 1 0 1 1 1 0 Zinc-binding Pkinase PF00069.25 RLN31363.1 - 1.1e-10 41.3 0.0 6.1e-10 38.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 RLN31363.1 - 0.00032 19.6 0.0 0.00032 19.6 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase DUF4327 PF14217.6 RLN31363.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4327) DUF2868 PF11067.8 RLN31363.1 - 2.1 7.8 4.7 3.2 7.2 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Cu-oxidase_2 PF07731.14 RLN31382.1 - 1.4e-13 50.8 1.0 1e-12 48.0 1.0 2.3 1 1 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN31382.1 - 8.2e-13 48.4 1.6 1.3e-07 31.6 0.1 3.6 3 0 0 3 3 3 3 Multicopper oxidase zf-CCHC PF00098.23 RLN31384.1 - 1.7e-06 27.8 1.3 1.7e-06 27.8 1.3 1.8 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.17 RLN31384.1 - 6.8e-06 26.3 0.1 1.3e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 RLN31384.1 - 0.00028 20.6 5.2 0.00048 19.9 5.2 1.3 1 0 0 1 1 1 1 Zinc knuckle PNMA PF14893.6 RLN31384.1 - 0.028 13.8 0.0 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 PNMA zf-C2H2_10 PF16588.5 RLN31384.1 - 0.22 11.3 0.2 0.41 10.4 0.2 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger SlyX PF04102.12 RLN31385.1 - 9.6e-05 22.9 5.2 0.0067 17.0 0.6 3.1 1 1 2 3 3 3 1 SlyX HIP1_clath_bdg PF16515.5 RLN31385.1 - 0.001 19.7 5.5 0.001 19.7 5.5 2.0 1 1 1 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Bacillus_HBL PF05791.11 RLN31385.1 - 0.0011 18.8 2.5 0.002 18.0 0.7 1.9 1 1 1 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) Spc7 PF08317.11 RLN31385.1 - 0.0016 17.4 7.5 0.0025 16.8 7.5 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein EzrA PF06160.12 RLN31385.1 - 0.0027 16.0 6.7 0.045 11.9 5.9 2.4 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA MbeD_MobD PF04899.12 RLN31385.1 - 0.0047 17.0 0.6 0.034 14.2 0.2 2.2 1 1 1 2 2 2 1 MbeD/MobD like Fib_alpha PF08702.10 RLN31385.1 - 0.0052 17.0 8.0 0.0052 17.0 8.0 1.7 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family ATP-grasp_2 PF08442.10 RLN31385.1 - 0.0099 15.5 0.4 0.018 14.6 0.4 1.4 1 0 0 1 1 1 1 ATP-grasp domain DUF4618 PF15397.6 RLN31385.1 - 0.011 15.2 8.3 0.017 14.5 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) AAA_23 PF13476.6 RLN31385.1 - 0.014 15.9 2.1 0.017 15.6 2.1 1.1 1 0 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.9 RLN31385.1 - 0.058 13.4 8.4 0.12 12.4 8.4 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Wtap PF17098.5 RLN31385.1 - 0.06 13.3 7.1 0.053 13.4 4.8 2.1 2 1 0 2 2 2 0 WTAP/Mum2p family ATG16 PF08614.11 RLN31385.1 - 0.067 13.4 6.1 0.18 12.0 6.1 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 RLN31385.1 - 0.071 13.4 5.7 0.25 11.6 5.2 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mt_ATP-synt_D PF05873.12 RLN31385.1 - 0.077 12.8 1.3 0.13 12.1 1.3 1.4 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Spc42p PF11544.8 RLN31385.1 - 0.084 12.9 2.6 0.16 12.0 0.6 2.5 1 1 1 2 2 2 0 Spindle pole body component Spc42p FAM184 PF15665.5 RLN31385.1 - 0.17 11.7 9.1 2.1 8.1 0.8 2.2 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Cnn_1N PF07989.11 RLN31385.1 - 0.35 11.1 9.5 2 8.6 4.7 3.1 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 Syntaxin-6_N PF09177.11 RLN31385.1 - 0.37 11.4 5.0 1.6 9.4 4.3 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 RLN31385.1 - 0.39 10.8 7.7 0.31 11.1 3.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Phasin PF05597.11 RLN31385.1 - 0.4 10.7 4.2 0.41 10.7 2.1 2.0 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) FlaC_arch PF05377.11 RLN31385.1 - 0.55 10.7 14.9 0.55 10.7 0.3 4.7 3 3 2 5 5 5 0 Flagella accessory protein C (FlaC) LPP PF04728.13 RLN31385.1 - 0.59 10.6 4.3 2.4 8.6 0.2 3.2 2 1 1 3 3 3 0 Lipoprotein leucine-zipper Spc24 PF08286.11 RLN31385.1 - 0.87 9.9 6.0 0.23 11.7 0.8 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF16 PF01519.16 RLN31385.1 - 1 9.9 8.2 38 4.8 8.2 2.2 1 1 0 1 1 1 0 Protein of unknown function DUF16 TMPIT PF07851.13 RLN31385.1 - 3 7.0 7.8 0.43 9.8 3.1 1.7 1 1 1 2 2 2 0 TMPIT-like protein Rax2 PF12768.7 RLN31386.1 - 0.0032 17.0 0.1 0.033 13.7 0.0 2.2 2 0 0 2 2 2 1 Cortical protein marker for cell polarity MFS_1 PF07690.16 RLN31386.1 - 0.0076 15.2 1.5 0.008 15.1 0.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_2_1 PF04971.12 RLN31386.1 - 0.082 12.9 0.4 0.21 11.6 0.4 1.8 1 0 0 1 1 1 0 Bacteriophage P21 holin S DUF2537 PF10801.8 RLN31386.1 - 2.6 8.3 7.5 0.59 10.4 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) Crisp PF08562.10 RLN31386.1 - 2.7 8.6 9.0 5.2 7.7 2.7 2.2 2 0 0 2 2 2 0 Crisp Cdh1_DBD_1 PF18196.1 RLN31421.1 - 0.04 14.2 0.1 0.12 12.7 0.0 1.8 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 TPR_1 PF00515.28 RLN31422.1 - 3.8e-12 45.5 7.4 0.0018 18.0 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN31422.1 - 6.2e-12 44.7 9.8 6e-05 22.8 0.7 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN31422.1 - 8.7e-09 34.9 4.8 0.00096 18.8 0.9 2.9 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 RLN31422.1 - 7.8e-06 25.7 5.8 0.24 11.7 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN31422.1 - 0.00069 19.9 4.8 0.0017 18.6 3.4 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN31422.1 - 0.013 16.3 7.1 1.3 10.0 1.3 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 RLN31422.1 - 0.038 14.1 3.1 0.085 13.0 1.7 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN31422.1 - 0.22 12.2 11.0 0.65 10.7 3.2 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 RLN31422.1 - 0.33 11.4 3.8 5.4 7.6 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN31422.1 - 0.36 10.8 5.5 0.68 9.9 0.6 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_3_C PF01915.22 RLN31436.1 - 1.8e-98 328.5 0.0 7.6e-50 169.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 RLN31436.1 - 1.8e-35 122.8 0.0 5.9e-35 121.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 RLN31436.1 - 4.1e-16 58.8 0.4 9.2e-09 35.3 0.1 2.9 3 0 0 3 3 3 2 Fibronectin type III-like domain Ig_GlcNase PF18368.1 RLN31436.1 - 0.0016 18.6 0.6 0.26 11.5 0.2 2.8 2 0 0 2 2 2 1 Exo-beta-D-glucosaminidase Ig-fold domain PEP_hydrolase PF09370.10 RLN31436.1 - 0.0039 16.5 0.1 1.3 8.2 0.1 2.3 2 0 0 2 2 2 2 Phosphoenolpyruvate hydrolase-like T6SS-SciN PF12790.7 RLN31436.1 - 0.0087 15.8 0.1 5.5 6.7 0.0 2.4 2 0 0 2 2 2 2 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 MtN3_slv PF03083.16 RLN31438.1 - 6e-40 135.2 26.7 6.4e-16 58.2 1.8 3.8 4 0 0 4 4 4 3 Sugar efflux transporter for intercellular exchange Prominin PF05478.11 RLN31438.1 - 0.043 11.8 0.7 0.063 11.2 0.7 1.1 1 0 0 1 1 1 0 Prominin TMEMspv1-c74-12 PF11044.8 RLN31438.1 - 6.5 6.8 7.5 2.8 8.0 3.2 2.4 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein MtN3_slv PF03083.16 RLN31439.1 - 9.1e-30 102.5 17.1 4.6e-20 71.5 4.7 2.4 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RLN31439.1 - 0.075 12.8 0.4 0.075 12.8 0.4 3.5 4 0 0 4 4 4 0 PQ loop repeat MtN3_slv PF03083.16 RLN31440.1 - 3.6e-29 100.6 7.9 6.6e-22 77.3 1.2 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange DUF4149 PF13664.6 RLN31440.1 - 1.3 9.4 7.8 1.1 9.7 3.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4149) MtN3_slv PF03083.16 RLN31441.1 - 9.4e-32 108.9 9.4 3.2e-20 72.0 2.9 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RLN31441.1 - 9.4e-06 25.3 2.5 0.09 12.6 0.2 2.8 2 0 0 2 2 2 2 PQ loop repeat DUF3087 PF11286.8 RLN31441.1 - 1.5 8.3 4.7 8.6 5.8 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3087) DUF1129 PF06570.11 RLN31441.1 - 3.6 7.0 6.3 6.4 6.2 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) MtN3_slv PF03083.16 RLN31442.1 - 5e-36 122.6 13.4 9.5e-22 76.8 3.9 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RLN31442.1 - 0.034 13.9 7.9 0.26 11.1 0.1 3.5 3 1 0 3 3 3 0 PQ loop repeat QCR10 PF09796.9 RLN31442.1 - 0.037 14.1 1.5 0.073 13.1 0.1 2.2 2 1 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) MtN3_slv PF03083.16 RLN31443.1 - 2.3e-31 107.7 10.4 4.4e-18 65.1 0.6 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RLN31443.1 - 1.3e-05 24.9 5.9 0.00014 21.6 0.4 3.0 3 0 0 3 3 3 2 PQ loop repeat DUF4191 PF13829.6 RLN31443.1 - 0.98 8.7 5.5 0.21 10.9 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4191) MtN3_slv PF03083.16 RLN31444.1 - 1.7e-60 201.1 36.2 6.8e-21 74.1 1.0 4.4 4 0 0 4 4 4 4 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RLN31444.1 - 0.00093 18.9 17.0 0.033 14.0 0.5 4.7 5 0 0 5 5 5 2 PQ loop repeat TRAP-gamma PF07074.12 RLN31444.1 - 2.7 7.5 9.8 0.73 9.4 0.7 2.9 3 0 0 3 3 3 0 Translocon-associated protein, gamma subunit (TRAP-gamma) TMEM173 PF15009.6 RLN31444.1 - 4.1 6.5 12.5 23 4.0 0.6 4.4 4 1 1 5 5 5 0 Transmembrane protein 173 MtN3_slv PF03083.16 RLN31445.1 - 9.6e-16 57.6 7.9 2.2e-11 43.6 2.0 2.5 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange MtN3_slv PF03083.16 RLN31446.1 - 2.1e-13 50.1 7.2 2.3e-11 43.6 1.7 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange MerC PF03203.14 RLN31446.1 - 0.038 14.4 5.5 0.042 14.3 2.0 2.2 2 0 0 2 2 2 0 MerC mercury resistance protein MtN3_slv PF03083.16 RLN31447.1 - 1e-37 128.0 7.2 1e-20 73.5 0.6 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RLN31447.1 - 0.00022 20.9 9.3 0.02 14.6 0.0 3.7 3 1 1 4 4 4 2 PQ loop repeat YtpI PF14007.6 RLN31447.1 - 0.025 14.7 2.7 0.038 14.1 0.6 2.2 1 1 0 2 2 2 0 YtpI-like protein His_Phos_2 PF00328.22 RLN31448.1 - 3.6e-32 112.2 0.0 5.8e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MtN3_slv PF03083.16 RLN31449.1 - 8.8e-26 89.8 13.2 1.3e-16 60.4 2.5 2.4 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Bac_export_2 PF01312.19 RLN31449.1 - 0.71 9.0 9.1 1 8.5 9.1 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Glyco_hydro_28 PF00295.17 RLN31458.1 - 3.7e-72 243.1 18.7 4.7e-72 242.8 18.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 NosD PF05048.13 RLN31458.1 - 2.2e-07 30.4 21.7 4.4e-07 29.4 12.0 2.2 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Glyco_hydro_28 PF00295.17 RLN31459.1 - 8.5e-72 241.9 18.8 1.1e-71 241.6 18.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 NosD PF05048.13 RLN31459.1 - 2.2e-07 30.4 21.7 4.4e-07 29.4 12.0 2.2 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) LCM PF04072.14 RLN31460.1 - 5.6e-40 137.3 0.0 7.7e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase PQ-loop PF04193.14 RLN31461.1 - 2.6e-12 46.3 0.7 2.6e-12 46.3 0.7 1.8 2 0 0 2 2 2 1 PQ loop repeat MtN3_slv PF03083.16 RLN31461.1 - 0.0069 16.4 2.4 0.01 15.8 1.8 1.6 1 1 1 2 2 2 1 Sugar efflux transporter for intercellular exchange MIG-14_Wnt-bd PF06664.12 RLN31461.1 - 0.011 15.0 1.6 0.017 14.3 1.0 1.5 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion Ank_2 PF12796.7 RLN31462.1 - 7.2e-32 109.8 9.8 1.6e-09 38.2 0.7 6.5 1 1 6 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN31462.1 - 3.6e-28 97.3 19.0 0.01 16.2 0.2 11.4 7 2 5 12 12 12 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN31462.1 - 2.4e-27 95.0 17.0 4.4e-05 23.9 0.1 10.3 9 2 1 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN31462.1 - 2.7e-18 64.2 8.1 1.8 9.4 0.0 12.1 14 0 0 14 14 14 5 Ankyrin repeat Ank PF00023.30 RLN31462.1 - 5.9e-06 26.5 6.9 37 5.0 0.0 8.9 6 2 2 8 8 8 0 Ankyrin repeat Pkinase PF00069.25 RLN31463.1 - 3.7e-29 101.9 0.0 4.1e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN31463.1 - 3.9e-26 91.9 0.0 4.7e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN31463.1 - 0.0002 20.3 0.0 0.00025 20.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 RLN31463.1 - 0.0034 17.0 0.0 0.0046 16.6 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 RLN31463.1 - 0.0081 16.1 0.2 0.012 15.5 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN31463.1 - 0.071 12.5 0.1 0.097 12.0 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 RLN31484.1 - 1.5e-78 259.4 14.4 3.8e-12 46.6 0.3 7.2 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN31484.1 - 1e-65 217.3 6.3 1.4e-07 31.9 0.0 9.1 3 3 2 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN31484.1 - 5.3e-53 176.4 17.7 3.4e-06 27.2 0.1 12.9 1 1 12 13 13 13 13 Ankyrin repeats (many copies) Ank PF00023.30 RLN31484.1 - 2.1e-48 160.7 26.8 0.0001 22.6 0.0 13.5 14 0 0 14 14 14 9 Ankyrin repeat Ank_3 PF13606.6 RLN31484.1 - 6.2e-47 152.1 7.4 0.021 15.3 0.0 14.3 14 0 0 14 14 14 10 Ankyrin repeat SIP PF04954.13 RLN31484.1 - 0.0034 17.9 0.7 5.7 7.5 0.0 4.5 3 1 1 5 5 5 1 Siderophore-interacting protein GAF_3 PF13492.6 RLN31484.1 - 0.018 15.4 1.2 0.39 11.1 0.0 3.5 3 2 1 4 4 4 0 GAF domain PK_C PF02887.16 RLN31484.1 - 0.061 13.6 2.3 55 4.0 0.0 4.4 2 2 0 3 3 3 0 Pyruvate kinase, alpha/beta domain Imm_superinfect PF14373.6 RLN31484.1 - 0.098 12.6 0.1 2e+02 2.0 0.0 4.9 6 0 0 6 6 6 0 Superinfection immunity protein Pkinase PF00069.25 RLN31487.1 - 3.4e-55 187.3 0.2 7.8e-54 182.8 0.2 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN31487.1 - 2.9e-37 128.4 0.0 2.9e-36 125.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN31487.1 - 6.4e-06 25.2 0.5 2e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Fez1 PF06818.15 RLN31487.1 - 0.00032 21.2 0.9 0.00057 20.4 0.9 1.4 1 0 0 1 1 1 1 Fez1 Rabaptin PF03528.15 RLN31487.1 - 0.0027 16.5 6.8 0.0041 15.9 6.8 1.1 1 0 0 1 1 1 1 Rabaptin DUF3552 PF12072.8 RLN31487.1 - 0.077 12.4 5.8 0.14 11.6 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) APH PF01636.23 RLN31487.1 - 1.3 8.9 4.9 4.6 7.1 0.1 2.8 3 0 0 3 3 3 0 Phosphotransferase enzyme family LMSTEN PF07988.12 RLN31487.1 - 1.6 8.2 5.3 4.9 6.7 5.3 1.8 1 0 0 1 1 1 0 LMSTEN motif zf-C3HC4_3 PF13920.6 RLN31488.1 - 2.2e-17 62.7 10.9 2.6e-17 62.4 10.9 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN31488.1 - 5.6e-09 35.7 11.4 7.6e-09 35.3 11.4 1.1 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 RLN31488.1 - 1.7e-07 31.5 13.6 2.1e-07 31.1 13.6 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RLN31488.1 - 3.4e-06 26.8 14.6 4.9e-06 26.3 14.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN31488.1 - 8.6e-05 22.4 11.5 0.00012 21.9 11.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RLN31488.1 - 0.00069 19.4 12.9 0.0009 19.0 12.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 RLN31488.1 - 0.0073 16.3 1.3 0.0073 16.3 1.3 1.8 1 1 1 2 2 2 2 Double zinc ribbon DUF1644 PF07800.12 RLN31488.1 - 0.03 14.4 7.7 1.4 9.0 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-P11 PF03854.14 RLN31488.1 - 0.1 12.3 9.5 0.14 11.8 9.5 1.3 1 1 0 1 1 1 0 P-11 zinc finger zf-RING_UBOX PF13445.6 RLN31488.1 - 0.43 10.6 9.5 0.54 10.3 6.1 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_11 PF17123.5 RLN31488.1 - 0.49 10.2 9.8 0.74 9.6 4.0 3.3 2 2 1 3 3 3 0 RING-like zinc finger zf-RING_4 PF14570.6 RLN31488.1 - 0.51 10.2 8.1 0.87 9.4 8.1 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Phage_integrase PF00589.22 RLN31497.1 - 0.013 15.3 0.0 0.076 12.8 0.0 2.1 1 1 0 1 1 1 0 Phage integrase family CBS PF00571.28 RLN31498.1 - 0.19 12.2 0.5 10 6.6 0.1 2.7 3 0 0 3 3 3 0 CBS domain Arm PF00514.23 RLN31499.1 - 6e-33 111.8 6.0 7.3e-05 22.7 0.1 10.6 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat Pkinase PF00069.25 RLN31499.1 - 1.1e-24 87.3 0.0 2.2e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN31499.1 - 5e-24 85.0 0.0 7.8e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 RLN31499.1 - 6.3e-12 45.7 18.9 0.0043 17.4 2.0 6.8 5 2 3 8 8 8 6 HEAT repeats HEAT_EZ PF13513.6 RLN31499.1 - 6e-10 39.4 26.5 3.3e-05 24.3 0.2 7.5 6 3 3 9 9 9 5 HEAT-like repeat HEAT PF02985.22 RLN31499.1 - 5.5e-07 29.3 16.9 1 9.8 0.0 8.8 12 0 0 12 12 12 3 HEAT repeat Glycos_trans_3N PF02885.17 RLN31499.1 - 0.0046 16.8 0.7 3.8 7.4 0.0 3.7 4 0 0 4 4 4 1 Glycosyl transferase family, helical bundle domain Tex_N PF09371.10 RLN31499.1 - 0.1 12.3 1.2 42 3.7 0.1 3.6 2 1 2 4 4 4 0 Tex-like protein N-terminal domain HEAT_PBS PF03130.16 RLN31499.1 - 0.11 13.3 24.5 10 7.2 0.4 8.5 9 0 0 9 9 9 0 PBS lyase HEAT-like repeat Kinase-like PF14531.6 RLN31499.1 - 0.16 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like NOA36 PF06524.12 RLN31515.1 - 0.36 10.1 16.2 0.74 9.1 16.2 1.5 1 0 0 1 1 1 0 NOA36 protein TLD PF07534.16 RLN31516.1 - 2.2e-32 112.1 0.1 3.5e-32 111.5 0.1 1.3 1 0 0 1 1 1 1 TLD GST_N_2 PF13409.6 RLN31521.1 - 3.9e-12 46.3 0.0 1.5e-09 38.0 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 RLN31521.1 - 2.6e-10 40.6 0.0 1.5e-05 25.3 0.0 2.6 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RLN31521.1 - 6.6e-09 36.0 0.2 8.4e-05 22.8 0.0 3.4 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN31521.1 - 0.024 14.7 0.1 0.054 13.5 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AAA_33 PF13671.6 RLN31522.1 - 9.8e-20 71.2 0.0 5.7e-19 68.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RLN31522.1 - 5e-09 35.7 0.1 1e-07 31.4 0.0 2.6 2 1 0 2 2 2 1 Zeta toxin CPT PF07931.12 RLN31522.1 - 0.00037 20.4 0.0 0.0012 18.7 0.0 1.8 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 RLN31522.1 - 0.0025 18.2 0.1 0.0062 17.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RLN31522.1 - 0.0048 17.4 0.0 0.013 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Ank_4 PF13637.6 RLN31523.1 - 2.8e-13 50.1 0.0 2e-08 34.6 0.0 2.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN31523.1 - 6.2e-11 42.7 0.0 7.3e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 RLN31523.1 - 9.1e-11 41.7 0.0 3e-05 24.2 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 RLN31523.1 - 1.9e-10 40.8 0.2 4e-10 39.7 0.2 1.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN31523.1 - 1e-08 34.7 0.1 0.00011 22.3 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Nucleoporin_FG PF13634.6 RLN31524.1 - 3.1e-12 47.2 47.5 0.00023 21.9 0.8 8.3 5 2 3 8 8 8 6 Nucleoporin FG repeat region WD40 PF00400.32 RLN31525.1 - 5.1e-60 198.0 22.3 1.6e-08 35.1 0.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN31525.1 - 4.2e-17 62.2 0.2 0.00025 21.3 0.0 6.2 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN31525.1 - 1.4e-08 34.1 6.9 0.0088 15.0 0.1 5.8 1 1 6 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 RLN31525.1 - 1.8e-05 24.7 0.0 0.00024 21.0 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 RLN31525.1 - 0.0065 15.2 5.3 0.28 9.8 0.0 3.9 1 1 4 5 5 5 1 Nucleoporin Nup120/160 SOG2 PF10428.9 RLN31525.1 - 0.76 8.9 10.6 1.2 8.2 10.6 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein SPG48 PF14764.6 RLN31526.1 - 0.068 13.6 0.2 0.2 12.1 0.1 1.9 1 1 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking RTTN_N PF14726.6 RLN31526.1 - 0.077 13.8 0.8 0.23 12.3 0.8 1.8 1 0 0 1 1 1 0 Rotatin, an armadillo repeat protein, centriole functioning DUF445 PF04286.12 RLN31526.1 - 0.32 10.8 9.0 3.9 7.2 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF445) MFS_4 PF06779.14 RLN31526.1 - 0.51 9.6 4.5 13 4.9 0.1 3.0 3 0 0 3 3 3 0 Uncharacterised MFS-type transporter YbfB EF-G-binding_N PF07299.11 RLN31526.1 - 0.9 10.1 4.1 4 8.0 1.2 3.1 2 1 0 2 2 2 0 Elongation factor G-binding protein, N-terminal DUF3619 PF12279.8 RLN31526.1 - 1.8 8.9 7.5 4.9 7.5 1.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3619) TetR_C_16 PF17920.1 RLN31526.1 - 5.7 7.2 9.6 6.8 7.0 0.3 3.8 3 1 1 4 4 4 0 Tetracyclin repressor-like, C-terminal domain DnaI_N PF07319.11 RLN31526.1 - 8.4 7.1 7.8 54 4.5 0.0 4.0 4 1 1 5 5 5 0 Primosomal protein DnaI N-terminus HTH_Tnp_Tc5 PF03221.16 RLN31527.1 - 0.0012 18.9 0.0 0.0027 17.7 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DivIC PF04977.15 RLN31528.1 - 0.018 14.8 5.2 0.018 14.8 5.2 2.6 2 1 0 2 2 2 0 Septum formation initiator ATG16 PF08614.11 RLN31528.1 - 0.026 14.7 20.9 0.038 14.2 20.9 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) ISG65-75 PF11727.8 RLN31528.1 - 0.042 13.1 6.5 0.062 12.5 6.5 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein ERM PF00769.19 RLN31528.1 - 0.06 13.2 30.1 0.019 14.8 25.0 2.0 1 1 0 2 2 2 0 Ezrin/radixin/moesin family AAA_13 PF13166.6 RLN31528.1 - 0.2 10.3 7.0 0.23 10.1 7.0 1.1 1 0 0 1 1 1 0 AAA domain CENP-H PF05837.12 RLN31528.1 - 0.33 11.4 20.6 2.2 8.7 3.5 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) V_ATPase_I PF01496.19 RLN31528.1 - 0.45 8.4 2.6 0.5 8.2 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMCO5 PF14992.6 RLN31528.1 - 0.83 9.2 10.8 0.5 9.9 6.6 2.1 1 1 1 2 2 2 0 TMCO5 family DUF5340 PF17275.2 RLN31528.1 - 1.7 8.9 8.8 0.3 11.2 4.8 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5340) DUF4200 PF13863.6 RLN31528.1 - 3.5 8.0 18.0 0.8 10.1 14.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) TMF_TATA_bd PF12325.8 RLN31528.1 - 4.9 7.4 17.7 21 5.4 14.2 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 RLN31528.1 - 7.7 6.9 18.8 11 6.4 18.7 1.5 1 1 0 1 1 1 0 Fez1 CP12 PF02672.15 RLN31528.1 - 9.7 7.0 11.0 0.79 10.5 5.5 2.1 2 0 0 2 2 2 0 CP12 domain Pkinase PF00069.25 RLN31536.1 - 2.7e-15 56.5 0.0 3.2e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN31536.1 - 4.5e-10 39.3 0.0 6.1e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF547 PF04784.14 RLN31537.1 - 4.2e-10 39.7 0.0 1e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF547 TFIIE-A_C PF11521.8 RLN31537.1 - 1.4 9.2 6.4 0.19 12.0 1.5 2.0 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha DUF3357 PF11837.8 RLN31538.1 - 0.84 10.1 3.3 10 6.7 3.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) HA PF03457.14 RLN31540.1 - 4.4e-15 55.8 0.0 4.7e-05 23.6 0.0 3.3 3 0 0 3 3 3 3 Helicase associated domain HA PF03457.14 RLN31541.1 - 3.1e-29 101.1 5.6 3.8e-07 30.3 0.3 5.2 5 0 0 5 5 5 5 Helicase associated domain PG_binding_2 PF08823.11 RLN31541.1 - 0.017 15.4 0.2 1.4 9.3 0.0 3.2 3 0 0 3 3 3 0 Putative peptidoglycan binding domain RecA PF00154.21 RLN31542.1 - 3e-113 377.7 1.6 4.8e-109 363.9 0.4 2.1 1 1 1 2 2 2 2 recA bacterial DNA recombination protein Rad51 PF08423.11 RLN31542.1 - 1.1e-06 28.2 0.3 1.4e-05 24.5 0.3 2.0 1 1 0 1 1 1 1 Rad51 ATPase_2 PF01637.18 RLN31542.1 - 7.3e-06 26.1 0.2 2.5e-05 24.3 0.0 2.0 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea ATPase PF06745.13 RLN31542.1 - 0.00054 19.4 1.5 0.045 13.1 0.1 3.0 2 1 0 2 2 2 1 KaiC AAA_24 PF13479.6 RLN31542.1 - 0.008 15.9 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RLN31542.1 - 0.013 15.9 0.2 0.013 15.9 0.2 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 RLN31542.1 - 0.018 14.7 1.0 1.1 8.8 1.0 2.4 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 RLN31542.1 - 0.026 15.0 0.0 0.058 13.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPgrasp_N PF18130.1 RLN31542.1 - 0.053 14.1 1.6 0.26 11.9 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp N-terminal domain CobU PF02283.16 RLN31542.1 - 0.081 12.5 0.0 0.23 11.0 0.0 1.8 1 1 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Cyclin_C PF02984.19 RLN31544.1 - 1.1e-22 80.4 0.9 1.4e-22 80.0 0.9 1.2 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 RLN31544.1 - 1.9e-06 27.6 2.2 0.00014 21.6 0.2 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain COPIIcoated_ERV PF07970.12 RLN31559.1 - 2.3e-31 109.4 3.0 2.8e-31 109.1 3.0 1.0 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter WD40 PF00400.32 RLN31568.1 - 1.5e-12 47.8 13.2 0.0032 18.3 0.1 6.2 3 2 3 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN31568.1 - 6.2e-08 32.8 0.4 0.093 13.0 0.0 4.4 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RLN31568.1 - 0.00099 19.0 0.4 12 5.7 0.0 3.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 RLN31568.1 - 0.0016 18.3 0.0 0.67 10.0 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 RLN31568.1 - 0.11 11.2 0.1 0.98 8.1 0.0 2.3 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region ThiF PF00899.21 RLN31569.1 - 1.3e-37 129.5 0.2 4.3e-37 127.8 0.0 1.8 1 1 1 2 2 2 1 ThiF family Pex14_N PF04695.13 RLN31569.1 - 0.0047 17.6 0.3 0.024 15.3 0.1 2.1 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region TrkA_N PF02254.18 RLN31569.1 - 0.02 15.2 0.1 0.072 13.4 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 RLN31569.1 - 0.024 14.9 1.5 0.11 12.7 1.5 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 RLN31569.1 - 0.031 14.4 0.1 0.069 13.2 0.1 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 RLN31569.1 - 0.04 13.2 0.3 0.068 12.4 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 RLN31569.1 - 0.076 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Enkurin PF13864.6 RLN31569.1 - 0.11 13.0 0.1 0.27 11.7 0.1 1.6 1 0 0 1 1 1 0 Calmodulin-binding ApbA PF02558.16 RLN31569.1 - 0.13 12.0 0.1 0.27 10.9 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Hydrolase_like PF13242.6 RLN31570.1 - 8.8e-21 73.8 0.0 3.2e-20 71.9 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 RLN31570.1 - 0.0004 20.5 0.0 0.0008 19.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 RLN31570.1 - 0.0004 20.4 0.0 0.0012 18.9 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RLN31570.1 - 0.00041 20.7 0.0 0.0023 18.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 RLN31570.1 - 0.073 12.7 0.0 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase DDE_1 PF03184.19 RLN31571.1 - 7.6e-13 48.5 0.0 1.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease CENP-B_N PF04218.13 RLN31571.1 - 2.4e-05 23.9 0.4 4.5e-05 23.0 0.4 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc5 PF03221.16 RLN31571.1 - 0.00037 20.5 0.0 0.00084 19.3 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.6 RLN31571.1 - 0.008 16.3 0.0 0.023 14.8 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 RLN31571.1 - 0.069 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain GntR PF00392.21 RLN31571.1 - 0.099 12.3 0.0 0.36 10.5 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_38 PF13936.6 RLN31571.1 - 0.17 11.7 0.2 0.4 10.5 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Ribonuc_P_40 PF08584.11 RLN31572.1 - 5.4e-69 232.6 0.0 6.4e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit SET PF00856.28 RLN31573.1 - 5.3e-09 36.7 0.0 1.5e-08 35.3 0.0 1.8 1 1 0 1 1 1 1 SET domain SseC PF04888.12 RLN31573.1 - 0.03 13.9 0.1 0.51 9.9 0.0 2.1 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family ClpB_D2-small PF10431.9 RLN31575.1 - 0.015 15.4 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein SEO_N PF14576.6 RLN31576.1 - 0.0039 16.4 0.1 0.0049 16.1 0.1 1.1 1 0 0 1 1 1 1 Sieve element occlusion N-terminus TPR_16 PF13432.6 RLN31577.1 - 1e-10 42.0 39.2 0.00027 21.5 1.4 11.5 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN31577.1 - 6.6e-09 35.3 25.7 0.41 11.0 0.1 12.5 13 0 0 13 13 13 3 Tetratricopeptide repeat TPR_17 PF13431.6 RLN31577.1 - 3.1e-05 24.0 28.0 0.0034 17.7 0.1 11.2 13 0 0 13 13 12 2 Tetratricopeptide repeat BTAD PF03704.17 RLN31577.1 - 0.00019 21.9 11.2 0.021 15.2 3.1 4.2 3 0 0 3 3 3 2 Bacterial transcriptional activator domain TPR_12 PF13424.6 RLN31577.1 - 0.00035 20.8 44.9 0.26 11.6 0.8 11.4 12 4 0 13 13 12 4 Tetratricopeptide repeat Sel1 PF08238.12 RLN31577.1 - 0.0022 18.6 1.4 0.38 11.5 0.0 4.1 3 0 0 3 3 3 1 Sel1 repeat Vps39_1 PF10366.9 RLN31577.1 - 0.0022 18.2 3.3 2.2 8.6 0.1 4.4 4 1 1 5 5 5 1 Vacuolar sorting protein 39 domain 1 TPR_1 PF00515.28 RLN31577.1 - 0.0086 15.9 43.3 0.13 12.1 0.1 12.9 15 0 0 15 15 15 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN31577.1 - 0.066 13.7 45.0 0.059 13.9 0.5 10.3 9 2 2 11 11 11 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN31577.1 - 0.098 12.9 24.8 1.8 8.9 1.4 7.6 8 0 0 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 RLN31577.1 - 0.11 13.2 0.3 0.11 13.2 0.3 7.6 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 RLN31577.1 - 0.16 11.7 0.0 0.16 11.7 0.0 9.0 11 0 0 11 11 10 0 TPR repeat TPR_2 PF07719.17 RLN31577.1 - 0.23 11.6 57.3 0.3 11.3 0.9 13.6 17 0 0 17 17 15 0 Tetratricopeptide repeat TPR_5 PF12688.7 RLN31577.1 - 0.54 10.5 7.4 0.13 12.5 0.5 3.2 3 0 0 3 3 3 0 Tetratrico peptide repeat TPR_14 PF13428.6 RLN31577.1 - 1 10.4 47.8 4.2 8.5 0.5 13.5 14 2 2 16 16 15 0 Tetratricopeptide repeat UPF0020 PF01170.18 RLN31579.1 - 9.3e-13 48.3 0.2 3.4e-11 43.2 0.0 3.0 2 2 1 3 3 3 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 RLN31579.1 - 0.00014 21.6 0.0 0.0018 18.0 0.0 2.2 2 0 0 2 2 2 1 DNA methylase MethyltransfD12 PF02086.15 RLN31579.1 - 0.055 13.1 0.0 0.47 10.1 0.0 2.1 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase Met_10 PF02475.16 RLN31579.1 - 0.096 12.4 0.1 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 Met-10+ like-protein N6_Mtase PF02384.16 RLN31579.1 - 0.11 11.7 0.0 2.7 7.2 0.0 2.2 2 0 0 2 2 2 0 N-6 DNA Methylase DLH PF01738.18 RLN31580.1 - 3.9e-20 72.3 0.1 4.9e-20 72.0 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 RLN31580.1 - 0.055 13.1 0.1 0.38 10.3 0.1 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN31580.1 - 0.06 12.6 0.0 0.42 9.8 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PAH PF02671.21 RLN31581.1 - 3.8e-05 23.7 0.2 5.5e-05 23.2 0.2 1.2 1 0 0 1 1 1 1 Paired amphipathic helix repeat HdeA PF06411.11 RLN31581.1 - 1.1 9.4 6.0 0.47 10.7 0.7 2.2 2 0 0 2 2 2 0 HdeA/HdeB family Pkinase_Tyr PF07714.17 RLN31586.1 - 7.1e-43 146.7 0.0 8.7e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN31586.1 - 1.6e-35 122.8 0.0 2.3e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 RLN31586.1 - 0.051 12.4 0.0 0.096 11.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase HTH_Tnp_1 PF01527.20 RLN31591.1 - 1.9e-07 31.3 3.9 3.4e-07 30.5 0.1 3.3 3 1 1 4 4 4 1 Transposase HTH_28 PF13518.6 RLN31591.1 - 4e-06 26.9 0.1 0.00019 21.5 0.2 2.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 RLN31591.1 - 0.00027 20.6 0.4 0.0016 18.2 0.1 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 RLN31591.1 - 0.0059 16.0 0.0 0.018 14.4 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 RLN31591.1 - 0.01 15.8 0.1 0.18 11.9 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn helix GerE PF00196.19 RLN31591.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family z-alpha PF02295.17 RLN31591.1 - 0.13 12.3 0.0 0.43 10.7 0.0 1.9 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain HTH_Tnp_Tc5 PF03221.16 RLN31591.1 - 0.15 12.1 3.7 2.2 8.3 0.0 3.8 3 2 0 3 3 3 0 Tc5 transposase DNA-binding domain DUF3693 PF12472.8 RLN31591.1 - 0.25 11.0 2.0 9.2 6.0 0.1 2.8 2 0 0 2 2 2 0 Phage related protein Aldolase_II PF00596.21 RLN31592.1 - 1.2e-07 31.9 0.4 1.9e-07 31.2 0.4 1.4 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Hydrolase PF00702.26 RLN31592.1 - 1.7e-06 28.5 0.1 3.9e-06 27.3 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 RLN31592.1 - 2e-06 28.0 0.0 3.4e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase STALD PF18185.1 RLN31592.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family IFT57 PF10498.9 RLN31593.1 - 4.4e-87 292.4 0.0 5.1e-87 292.2 0.0 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Myb_DNA-binding PF00249.31 RLN31594.1 - 1.3e-37 127.7 9.5 3.5e-12 46.3 0.7 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN31594.1 - 6.6e-32 109.6 1.2 1.3e-13 50.9 0.0 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 RLN31594.1 - 0.014 15.8 2.5 2.7 8.4 0.7 2.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 RLN31594.1 - 0.021 15.1 5.3 5.9 7.3 0.3 3.4 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 RLN31594.1 - 0.16 12.1 3.5 12 6.1 0.3 3.3 1 1 2 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain zf-C2H2 PF00096.26 RLN31594.1 - 0.26 11.8 0.6 0.57 10.7 0.6 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Sulfotransfer_1 PF00685.27 RLN31597.1 - 4.7e-09 36.1 0.3 2e-08 34.0 0.3 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RLN31597.1 - 1.8e-08 35.0 0.2 5.8e-06 26.8 0.2 2.7 2 0 0 2 2 2 2 Sulfotransferase family ABC2_membrane PF01061.24 RLN31597.1 - 1.8e-05 24.3 4.0 2.6e-05 23.7 4.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter DUF3098 PF11297.8 RLN31597.1 - 0.032 13.8 0.1 0.086 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) Penicil_amidase PF01804.18 RLN31597.1 - 0.045 12.7 0.0 0.064 12.2 0.0 1.1 1 0 0 1 1 1 0 Penicillin amidase ADK PF00406.22 RLN31602.1 - 9.1e-46 155.7 0.0 1.1e-45 155.4 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 RLN31602.1 - 2.4e-34 118.7 0.0 3e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RLN31602.1 - 1.3e-06 29.0 0.0 1.8e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RLN31602.1 - 9.7e-06 25.8 0.0 1.5e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 RLN31602.1 - 0.00032 20.0 0.0 0.0016 17.8 0.0 2.0 1 1 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.17 RLN31602.1 - 0.007 16.1 0.1 0.22 11.2 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase Ploopntkinase3 PF18751.1 RLN31602.1 - 0.034 14.1 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 RLN31602.1 - 0.062 13.6 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 RLN31602.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 RLN31602.1 - 0.14 12.4 0.5 0.73 10.1 0.4 2.2 1 1 1 2 2 2 0 AAA domain V-ATPase_H_C PF11698.8 RLN31603.1 - 5.8e-40 136.1 3.5 3.1e-38 130.5 1.1 2.8 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 RLN31603.1 - 1.3e-38 133.1 2.3 3.6e-37 128.3 0.2 2.2 2 0 0 2 2 2 2 V-ATPase subunit H Arm PF00514.23 RLN31603.1 - 4.4e-08 32.9 4.1 1 9.5 0.0 4.9 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat Bac_DNA_binding PF00216.21 RLN31603.1 - 9.6e-05 22.5 0.0 0.00037 20.6 0.0 2.1 1 0 0 1 1 1 1 Bacterial DNA-binding protein HEAT PF02985.22 RLN31603.1 - 0.0051 16.9 1.2 1.8 9.1 0.0 3.8 3 1 0 3 3 3 1 HEAT repeat Arm_2 PF04826.13 RLN31603.1 - 0.014 14.9 0.2 0.039 13.4 0.1 1.8 2 0 0 2 2 2 0 Armadillo-like HEAT_2 PF13646.6 RLN31603.1 - 0.016 15.6 0.1 1.5 9.3 0.0 3.2 3 1 0 3 3 3 0 HEAT repeats HEAT_EZ PF13513.6 RLN31603.1 - 0.016 15.7 1.4 13 6.4 0.0 3.8 3 0 0 3 3 3 0 HEAT-like repeat HU-CCDC81_bac_2 PF18175.1 RLN31603.1 - 0.021 14.7 0.0 0.058 13.3 0.0 1.7 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 AAA_lid_7 PF17867.1 RLN31603.1 - 0.08 13.2 0.4 0.29 11.4 0.1 2.1 2 0 0 2 2 2 0 Midasin AAA lid domain Sod_Ni PF09055.11 RLN31603.1 - 0.1 13.2 3.6 0.12 13.0 0.0 2.7 3 1 0 3 3 3 0 Nickel-containing superoxide dismutase PEX11 PF05648.14 RLN31604.1 - 9.2e-10 38.4 0.0 1.1e-09 38.1 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Phage_TAC_11 PF11836.8 RLN31604.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Phage tail tube protein, GTA-gp10 PH PF00169.29 RLN31605.1 - 0.0018 18.8 0.0 0.0032 17.9 0.0 1.4 1 0 0 1 1 1 1 PH domain DUF647 PF04884.14 RLN31606.1 - 2.1e-73 246.9 5.3 2.8e-73 246.5 5.3 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Pkinase PF00069.25 RLN31607.1 - 1.2e-52 178.9 0.0 1.9e-52 178.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN31607.1 - 4.5e-20 72.0 0.0 1.1e-19 70.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN31607.1 - 1.3e-05 24.7 0.0 2.6e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN31607.1 - 0.028 13.8 0.1 0.046 13.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 RLN31607.1 - 0.18 10.9 0.0 0.26 10.3 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Prefoldin_2 PF01920.20 RLN31608.1 - 1.2e-05 25.2 4.7 0.047 13.6 0.1 2.8 2 1 0 2 2 2 2 Prefoldin subunit DivIC PF04977.15 RLN31608.1 - 0.017 14.9 0.8 4.6 7.1 0.2 2.6 2 0 0 2 2 2 0 Septum formation initiator Peptidase_M14 PF00246.24 RLN31609.1 - 1.3e-40 140.1 0.0 1.7e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase SHIPPO-rpt PF07004.12 RLN31610.1 - 0.00019 22.2 0.7 0.32 12.0 0.1 3.0 2 0 0 2 2 2 2 Sperm-tail PG-rich repeat HMGL-like PF00682.19 RLN31611.1 - 1.6e-09 37.7 0.2 1.9e-09 37.5 0.2 1.1 1 0 0 1 1 1 1 HMGL-like PRA-PH PF01503.17 RLN31611.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase COG4 PF08318.12 RLN31612.1 - 1.3e-14 54.1 0.4 2.9e-13 49.6 0.4 2.6 1 1 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.13 RLN31613.1 - 3e-05 23.1 1.0 3e-05 23.1 1.0 1.4 2 0 0 2 2 2 1 RINT-1 / TIP-1 family DIL PF01843.19 RLN31613.1 - 0.043 14.1 0.2 0.11 12.8 0.2 1.7 1 0 0 1 1 1 0 DIL domain Symplekin_C PF12295.8 RLN31613.1 - 0.12 12.5 3.6 0.17 12.0 0.4 2.6 3 0 0 3 3 3 0 Symplekin tight junction protein C terminal MFS_1 PF07690.16 RLN31615.1 - 1.5e-26 93.2 33.0 1.5e-26 93.2 33.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Orai-1 PF07856.12 RLN31615.1 - 0.32 10.7 0.1 0.32 10.7 0.1 2.8 3 0 0 3 3 3 0 Mediator of CRAC channel activity Rieske PF00355.26 RLN31616.1 - 1.1e-08 34.9 0.5 2e-08 34.0 0.3 1.5 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 RLN31616.1 - 4.2e-08 33.1 0.0 5.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain zf-TAZ PF02135.16 RLN31617.1 - 4e-11 43.2 27.2 5.4e-09 36.4 13.2 3.3 2 2 0 2 2 2 2 TAZ zinc finger SAGA-Tad1 PF12767.7 RLN31617.1 - 3.8e-06 26.8 0.5 3.8e-06 26.8 0.5 3.0 3 0 0 3 3 3 1 Transcriptional regulator of RNA polII, SAGA, subunit U3snoRNP10 PF12397.8 RLN31618.1 - 3.1e-20 72.6 3.1 3.1e-20 72.6 3.1 5.6 5 1 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 RLN31618.1 - 0.0014 19.0 12.6 7.1 7.1 0.0 6.5 5 2 1 6 6 6 2 HEAT repeats HEAT PF02985.22 RLN31618.1 - 0.0083 16.3 0.4 0.0083 16.3 0.4 5.6 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 RLN31618.1 - 0.0088 16.5 4.3 0.031 14.8 0.0 4.3 4 0 0 4 4 4 1 HEAT-like repeat Cnd1 PF12717.7 RLN31618.1 - 0.026 14.5 13.2 1.3 9.0 0.0 5.2 3 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 TIR_3 PF18567.1 RLN31618.1 - 1.2 9.2 4.3 8 6.5 0.7 3.0 2 0 0 2 2 2 0 Toll/interleukin-1 receptor domain HMGL-like PF00682.19 RLN31619.1 - 1.4e-07 31.4 0.0 0.00013 21.7 0.0 2.5 1 1 0 2 2 2 2 HMGL-like Kinesin PF00225.23 RLN31631.1 - 1.3e-98 330.0 0.1 2e-98 329.4 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN31631.1 - 2.4e-27 95.7 0.0 6.8e-27 94.2 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Filament PF00038.21 RLN31631.1 - 0.00035 20.3 5.4 0.00035 20.3 5.4 2.7 3 0 0 3 3 3 1 Intermediate filament protein AAA_30 PF13604.6 RLN31631.1 - 0.0055 16.4 0.2 1.6 8.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain RILP PF11461.8 RLN31631.1 - 0.033 14.4 0.3 0.12 12.6 0.3 2.1 1 0 0 1 1 1 0 Rab interacting lysosomal protein Vps54_N PF10475.9 RLN31631.1 - 0.07 12.4 0.5 0.17 11.1 0.5 1.6 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex DUF3138 PF11336.8 RLN31631.1 - 0.29 9.7 7.3 0.15 10.7 4.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) TolA_bind_tri PF16331.5 RLN31631.1 - 3.4 7.8 17.0 2.3 8.4 0.2 4.1 4 0 0 4 4 4 0 TolA binding protein trimerisation Mt_ATP-synt_D PF05873.12 RLN31631.1 - 4.9 7.0 9.0 7.1 6.5 0.5 2.8 3 0 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) Latarcin PF10279.9 RLN31631.1 - 8.4 6.9 6.3 12 6.3 0.2 3.2 3 0 0 3 3 3 0 Latarcin precursor Vir_act_alpha_C PF10400.9 RLN31631.1 - 8.8 7.1 6.5 6.4 7.5 0.1 3.0 3 0 0 3 3 3 0 Virulence activator alpha C-term Aminotran_4 PF01063.19 RLN31632.1 - 3.6e-13 49.9 0.0 6.1e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Amino-transferase class IV Abhydrolase_3 PF07859.13 RLN31634.1 - 1.1e-34 120.2 0.6 1.9e-33 116.1 0.6 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN31634.1 - 3.7e-09 35.9 0.0 5.9e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 RLN31634.1 - 0.02 14.3 0.1 0.051 13.1 0.1 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family zf-CHCC PF10276.9 RLN31635.1 - 9.1e-16 57.6 1.4 1.2e-15 57.2 1.4 1.2 1 0 0 1 1 1 1 Zinc-finger domain FGase PF05013.12 RLN31635.1 - 0.046 13.9 0.1 0.071 13.3 0.1 1.3 1 1 0 1 1 1 0 N-formylglutamate amidohydrolase TPR_11 PF13414.6 RLN31636.1 - 0.0089 15.7 0.0 0.84 9.4 0.0 3.0 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.6 RLN31636.1 - 0.019 15.7 2.2 2 9.5 0.0 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN31636.1 - 0.088 12.7 0.0 1.1e+02 2.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Retrotrans_gag PF03732.17 RLN31639.1 - 0.023 15.0 0.2 0.047 14.0 0.2 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein DDE_1 PF03184.19 RLN31641.1 - 3.9e-14 52.7 0.0 9.3e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN31641.1 - 2.3e-06 27.5 0.1 7.3e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 RLN31641.1 - 6.4e-06 26.0 0.0 0.0012 18.6 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_1 PF01527.20 RLN31641.1 - 0.088 13.1 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 Transposase Actin PF00022.19 RLN31648.1 - 1.2e-140 468.8 0.0 3.9e-140 467.1 0.0 1.7 1 1 0 1 1 1 1 Actin C2 PF00168.30 RLN31652.1 - 1e-15 57.9 0.0 9.9e-08 32.2 0.0 3.6 4 0 0 4 4 4 2 C2 domain Pex24p PF06398.11 RLN31652.1 - 0.00018 20.6 0.0 0.21 10.5 0.0 2.2 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin Reticulon PF02453.17 RLN31652.1 - 0.00063 19.7 3.1 0.0024 17.9 0.0 2.4 2 0 0 2 2 2 1 Reticulon C1_1 PF00130.22 RLN31652.1 - 0.0021 17.9 3.3 0.0021 17.9 3.3 3.0 4 0 0 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CBP4 PF07960.11 RLN31652.1 - 0.014 15.3 0.1 0.039 13.8 0.1 1.7 1 0 0 1 1 1 0 CBP4 SET PF00856.28 RLN31653.1 - 2.5e-08 34.5 0.0 4.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 RLN31653.1 - 0.0038 17.9 0.5 0.0077 16.9 0.5 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding BRCT_2 PF16589.5 RLN31654.1 - 7.8e-09 35.8 0.0 1.5e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 RLN31654.1 - 7.5e-06 26.0 4.2 0.014 15.5 0.8 2.7 1 1 0 2 2 2 2 Rap1 Myb domain BRCT PF00533.26 RLN31654.1 - 0.01 16.2 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Rap1_C PF11626.8 RLN31654.1 - 0.13 12.3 0.4 0.59 10.2 0.0 2.4 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain TGT PF01702.18 RLN31655.1 - 2.5e-70 237.4 0.0 1.2e-68 231.8 0.0 2.0 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase AMP-binding PF00501.28 RLN31657.1 - 1.9e-54 184.9 0.0 6.6e-41 140.3 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme ACAS_N PF16177.5 RLN31657.1 - 4e-20 71.5 1.7 1.3e-19 69.9 1.7 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 RLN31657.1 - 1.4e-10 42.0 1.9 7.8e-10 39.6 0.2 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Tr-sialidase_C PF11052.8 RLN31657.1 - 1.5 9.0 5.7 3.3 7.9 5.7 1.6 1 0 0 1 1 1 0 Trans-sialidase of Trypanosoma hydrophobic C-terminal zf-RING_11 PF17123.5 RLN31658.1 - 0.031 14.0 1.5 0.063 13.0 1.5 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 RLN31658.1 - 0.051 13.9 5.3 0.13 12.5 5.3 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain Dsl1_N PF11988.8 RLN31658.1 - 0.069 12.1 0.5 0.097 11.6 0.5 1.1 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 N terminal zf-ANAPC11 PF12861.7 RLN31658.1 - 0.17 11.9 2.5 0.39 10.8 2.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 RLN31658.1 - 0.46 10.4 6.1 1.1 9.1 6.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN31658.1 - 3 8.2 9.3 6.9 7.1 9.3 1.7 1 0 0 1 1 1 0 Ring finger domain Pkinase PF00069.25 RLN31659.1 - 5.5e-15 55.4 0.0 6.3e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RLN31659.1 - 0.07 12.4 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like ATP-synt_ab PF00006.25 RLN31660.1 - 4.1e-64 216.2 0.0 6.6e-64 215.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 RLN31660.1 - 6.6e-09 36.2 0.5 1.5e-08 35.0 0.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF2263 PF10021.9 RLN31661.1 - 0.04 14.3 4.0 2 8.8 0.0 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2263) Med19 PF10278.9 RLN31661.1 - 0.32 10.9 6.3 0.75 9.7 6.3 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 PIF1 PF05970.14 RLN31662.1 - 2.1e-23 83.1 0.0 3.6e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 RLN31662.1 - 2.3e-10 41.0 0.1 2.3e-10 41.0 0.1 3.1 2 2 1 3 3 3 1 Helitron helicase-like domain at N-terminus DUF1534 PF07551.11 RLN31662.1 - 0.076 12.8 0.6 27 4.6 0.0 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1534) DnaJ PF00226.31 RLN31663.1 - 3.2e-13 49.6 0.0 7e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Ank_4 PF13637.6 RLN31671.1 - 3.9e-27 94.3 0.5 9.3e-11 42.0 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN31671.1 - 2.6e-23 82.4 0.4 6.1e-12 46.0 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN31671.1 - 5.9e-17 61.5 5.1 7.1e-09 35.8 0.2 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN31671.1 - 1e-16 60.6 1.0 0.00011 22.5 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 RLN31671.1 - 1.8e-16 58.5 0.4 0.0016 18.7 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat TPR_16 PF13432.6 RLN31671.1 - 0.028 15.1 0.1 0.093 13.4 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat MFS_1 PF07690.16 RLN31674.1 - 1.2e-09 37.6 8.4 1.6e-09 37.2 8.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Pex14_N PF04695.13 RLN31674.1 - 0.23 12.1 0.1 0.84 10.3 0.0 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SnoaL PF07366.12 RLN31691.1 - 1.1e-12 47.8 0.4 4.9e-12 45.7 0.0 2.2 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 RLN31691.1 - 3.5e-08 34.0 0.0 8e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like domain bZIP_1 PF00170.21 RLN31691.1 - 0.00014 21.9 2.8 0.00014 21.9 2.8 1.9 2 0 0 2 2 2 1 bZIP transcription factor KLRAQ PF10205.9 RLN31691.1 - 0.012 15.8 5.5 0.021 15.0 5.5 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein FapA PF03961.13 RLN31691.1 - 0.34 9.4 3.9 0.46 9.0 3.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4200 PF13863.6 RLN31691.1 - 2.3 8.6 8.7 1 9.8 2.2 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) Sel1 PF08238.12 RLN31692.1 - 9.9e-33 111.9 30.1 2.1e-06 28.2 0.4 11.0 12 0 0 12 12 12 9 Sel1 repeat U1snRNP70_N PF12220.8 RLN31693.1 - 0.19 12.4 1.8 0.75 10.5 1.8 2.0 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Vfa1 PF08432.10 RLN31693.1 - 3.6 7.9 7.1 7.1 6.9 7.1 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PUL PF08324.11 RLN31694.1 - 0.00046 19.5 0.5 0.0008 18.7 0.5 1.3 1 0 0 1 1 1 1 PUL domain ORC2 PF04084.14 RLN31694.1 - 0.025 13.5 0.1 0.042 12.8 0.1 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 2 WW PF00397.26 RLN31695.1 - 5.1e-07 29.7 0.7 1e-06 28.7 0.7 1.5 1 0 0 1 1 1 1 WW domain PQQ PF01011.21 RLN31695.1 - 0.12 12.4 0.2 0.26 11.3 0.2 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat E1-E2_ATPase PF00122.20 RLN31696.1 - 1.1e-49 168.5 2.1 1.1e-49 168.5 2.1 2.7 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 RLN31696.1 - 5.5e-49 166.4 1.5 7.3e-49 165.9 0.0 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 RLN31696.1 - 1.1e-24 88.0 1.2 8.5e-24 85.0 0.2 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN31696.1 - 1.9e-16 59.9 0.1 1.1e-15 57.5 0.0 2.3 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 RLN31696.1 - 4.6e-15 55.1 0.0 8.1e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RLN31696.1 - 0.00019 21.3 0.6 0.00037 20.3 0.6 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4870 PF09685.10 RLN31696.1 - 3 8.0 5.7 4 7.6 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4870) FAP206 PF12018.8 RLN31697.1 - 2e-82 276.8 0.0 1.3e-81 274.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function CH PF00307.31 RLN31698.1 - 2e-42 143.8 3.5 8.9e-22 77.3 0.0 3.5 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RLN31698.1 - 5.3e-12 45.4 0.2 5.7e-07 29.3 0.0 2.8 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_7 PF13499.6 RLN31698.1 - 6.7e-08 32.9 7.5 1.1e-07 32.2 5.3 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN31698.1 - 4e-07 29.4 4.9 0.00025 20.7 0.3 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RLN31698.1 - 1.6e-06 27.2 7.9 4.9e-05 22.6 0.7 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RLN31698.1 - 3.3e-05 23.7 7.9 0.016 15.0 2.9 2.8 1 1 1 2 2 2 2 EF-hand domain pair CH_2 PF06294.11 RLN31698.1 - 0.0015 18.6 0.8 0.22 11.7 0.0 3.0 2 0 0 2 2 2 1 CH-like domain in sperm protein Spectrin PF00435.21 RLN31698.1 - 0.02 15.3 29.6 0.046 14.2 0.6 5.7 4 2 1 5 5 5 0 Spectrin repeat zf-C2H2_9 PF16293.5 RLN31698.1 - 0.11 12.3 0.2 1.1 9.2 0.0 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) MerR-DNA-bind PF09278.11 RLN31698.1 - 0.18 12.4 2.6 16 6.1 0.0 4.7 4 0 0 4 4 4 0 MerR, DNA binding EF-hand_5 PF13202.6 RLN31698.1 - 0.93 9.1 5.1 0.27 10.8 0.3 2.6 2 0 0 2 2 2 0 EF hand NPV_P10 PF05531.12 RLN31698.1 - 2.2 8.8 17.4 38 4.8 0.1 6.4 5 2 1 6 6 6 0 Nucleopolyhedrovirus P10 protein LUC7 PF03194.15 RLN31698.1 - 8 6.0 18.4 2.8 7.5 12.8 2.8 2 1 0 2 2 2 0 LUC7 N_terminus cobW PF02492.19 RLN31699.1 - 2.1e-53 180.5 0.2 3.3e-53 179.9 0.2 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 RLN31699.1 - 1e-19 70.2 0.0 2.1e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 RLN31699.1 - 0.00083 19.3 0.0 0.67 9.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 RLN31699.1 - 0.0013 18.3 0.1 0.33 10.5 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 RLN31699.1 - 0.018 15.3 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RLN31699.1 - 0.035 14.5 0.0 0.088 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 RLN31699.1 - 0.081 12.7 0.2 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.10 RLN31699.1 - 0.082 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit T2SSE PF00437.20 RLN31699.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Methyltransf_25 PF13649.6 RLN31700.1 - 1.4e-07 32.1 0.1 5.9e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN31700.1 - 1.7e-05 24.7 0.0 3.3e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN31700.1 - 4e-05 23.5 0.0 0.00024 20.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN31700.1 - 4e-05 24.2 0.0 0.00011 22.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN31700.1 - 6.1e-05 23.7 0.0 0.00024 21.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain EF-hand_1 PF00036.32 RLN31702.1 - 0.013 15.0 0.0 0.49 10.1 0.0 2.8 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.6 RLN31702.1 - 0.051 13.5 0.0 1.1 9.4 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain RVT_1 PF00078.27 RLN31702.1 - 0.17 11.4 0.1 0.45 10.0 0.0 1.6 2 1 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) PX PF00787.24 RLN31703.1 - 3e-18 65.9 0.7 6e-18 64.9 0.7 1.5 1 0 0 1 1 1 1 PX domain zf-RING_UBOX PF13445.6 RLN31703.1 - 6.8e-09 35.6 0.4 1.4e-08 34.6 0.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 RLN31703.1 - 1.6e-08 34.8 2.0 2.8e-08 34.0 2.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 RLN31703.1 - 4.7e-08 32.9 1.6 8.2e-08 32.1 1.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RLN31703.1 - 1.1e-07 31.6 1.3 1.9e-07 30.8 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RLN31703.1 - 0.00022 21.3 0.9 0.00022 21.3 0.9 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 RLN31703.1 - 0.00037 20.3 2.8 0.0015 18.3 3.0 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN31703.1 - 0.00054 19.8 1.8 0.0013 18.5 1.8 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 RLN31703.1 - 0.00056 20.1 0.9 0.0012 19.1 0.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain APC_N_CC PF16689.5 RLN31703.1 - 0.00067 19.7 0.9 0.00067 19.7 0.9 3.5 2 1 2 4 4 3 1 Coiled-coil N-terminus of APC, dimerisation domain zf-RING_4 PF14570.6 RLN31703.1 - 0.055 13.3 4.3 0.19 11.6 4.4 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.21 RLN31703.1 - 0.21 11.7 2.6 0.6 10.3 2.6 1.7 1 1 0 1 1 1 0 FYVE zinc finger FANCL_C PF11793.8 RLN31703.1 - 0.34 11.1 1.4 0.7 10.1 1.4 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 RLN31703.1 - 0.63 9.9 10.2 4.1 7.3 10.2 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prim_Zn_Ribbon PF08273.12 RLN31703.1 - 1.1 9.6 3.7 20 5.6 0.6 2.4 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Rtf2 PF04641.12 RLN31703.1 - 3 7.1 10.9 1.8 7.9 4.2 2.6 1 1 2 3 3 3 0 Rtf2 RING-finger IBR PF01485.21 RLN31703.1 - 4 7.7 5.0 2.8 8.2 1.3 2.4 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain CENP-F_leu_zip PF10473.9 RLN31703.1 - 6.3 6.8 26.3 0.081 12.9 5.4 2.5 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CNDH2_C PF16858.5 RLN31704.1 - 0.0022 18.0 8.7 0.0029 17.5 8.7 1.1 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term WD40 PF00400.32 RLN31706.1 - 9.6e-39 130.7 19.0 3.3e-09 37.2 1.7 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN31706.1 - 3.7e-10 40.0 0.3 0.97 9.8 0.0 6.4 2 1 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN31706.1 - 0.0027 16.4 3.3 6.7 5.2 0.0 3.9 2 2 1 4 4 4 2 Nucleoporin Nup120/160 WD40_3 PF15911.5 RLN31706.1 - 0.032 14.3 0.0 0.18 11.8 0.0 2.3 3 0 0 3 3 3 0 WD domain, G-beta repeat Frtz PF11768.8 RLN31706.1 - 0.079 11.3 0.0 0.13 10.5 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz EF-hand_1 PF00036.32 RLN31707.1 - 4.3e-33 110.4 11.9 1.2e-09 37.0 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RLN31707.1 - 3.8e-29 101.0 6.3 8.1e-15 55.0 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN31707.1 - 1.9e-27 92.8 6.5 6e-10 38.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RLN31707.1 - 2.1e-23 80.7 11.0 1.9e-06 27.1 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 RLN31707.1 - 2.5e-21 75.2 12.4 1.1e-08 34.8 0.4 4.3 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 RLN31707.1 - 6.1e-10 39.3 0.2 0.00011 22.5 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 RLN31707.1 - 5.3e-07 29.5 5.2 0.024 14.6 0.7 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RLN31707.1 - 5.7e-05 23.4 0.2 0.36 11.2 0.2 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 RLN31707.1 - 9.2e-05 22.7 1.2 0.015 15.6 0.4 2.5 2 1 0 2 2 2 1 EF-hand domain SurA_N_3 PF13624.6 RLN31707.1 - 0.0029 17.4 1.6 0.51 10.1 0.5 2.1 1 1 1 2 2 2 2 SurA N-terminal domain Caleosin PF05042.13 RLN31707.1 - 0.0074 16.2 0.2 1.7 8.5 0.0 3.2 2 2 2 4 4 4 1 Caleosin related protein SurA_N_2 PF13623.6 RLN31707.1 - 0.0077 16.1 1.5 0.2 11.5 0.3 2.3 1 1 1 2 2 2 1 SurA N-terminal domain FGAR-AT_linker PF18072.1 RLN31707.1 - 0.011 16.2 0.1 1.1 9.9 0.0 2.5 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain PMBR PF09373.10 RLN31707.1 - 0.016 15.3 0.1 17 5.8 0.0 3.9 3 1 1 4 4 4 0 Pseudomurein-binding repeat Acetyltransf_11 PF13720.6 RLN31707.1 - 0.026 15.0 0.1 0.29 11.6 0.0 2.3 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 SUB1_ProdP9 PF18213.1 RLN31707.1 - 0.042 13.7 0.6 0.12 12.2 0.1 1.8 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 IF2_N PF04760.15 RLN31707.1 - 0.061 13.1 2.0 17 5.3 0.0 3.7 3 1 1 4 4 4 0 Translation initiation factor IF-2, N-terminal region Dockerin_1 PF00404.18 RLN31707.1 - 0.1 12.8 3.2 0.65 10.2 0.2 2.7 2 2 0 2 2 2 0 Dockerin type I domain DUF3008 PF11450.8 RLN31707.1 - 0.28 11.4 0.3 0.28 11.4 0.3 1.9 2 0 0 2 2 1 0 Protein of unknwon function (DUF3008) Proteasome PF00227.26 RLN31725.1 - 3.7e-30 104.8 0.0 5.2e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit TPR_1 PF00515.28 RLN31726.1 - 6.6e-09 35.2 1.4 0.00038 20.2 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN31726.1 - 1e-08 34.6 3.8 0.043 13.9 0.0 4.4 4 0 0 4 4 3 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN31726.1 - 1.1e-05 25.4 1.1 9.3e-05 22.4 0.0 2.8 2 1 1 3 3 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 RLN31726.1 - 1.1e-05 25.5 1.4 1.1e-05 25.5 1.4 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Arm PF00514.23 RLN31726.1 - 0.00023 21.1 8.8 2.2 8.4 0.0 6.0 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat TPR_19 PF14559.6 RLN31726.1 - 0.00029 21.3 0.8 0.00029 21.3 0.8 3.4 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN31726.1 - 0.0027 18.3 3.0 0.1 13.2 0.1 4.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN31726.1 - 0.026 14.9 0.5 3 8.4 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat HEAT_2 PF13646.6 RLN31726.1 - 0.052 13.9 9.9 0.46 10.9 0.0 5.9 4 1 2 6 6 6 0 HEAT repeats TPR_8 PF13181.6 RLN31726.1 - 0.11 12.8 0.6 44 4.7 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN31726.1 - 0.14 13.1 0.3 0.14 13.1 0.3 6.2 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN31726.1 - 0.19 12.0 3.3 0.42 10.9 0.4 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat HEAT PF02985.22 RLN31726.1 - 1.4 9.3 4.5 13 6.3 0.0 5.1 5 1 1 6 6 6 0 HEAT repeat UQ_con PF00179.26 RLN31727.1 - 1.1e-42 145.0 0.0 1.2e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RLN31727.1 - 6.7e-05 22.6 0.0 8.5e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B Tctex-1 PF03645.13 RLN31728.1 - 8.6e-25 87.0 0.1 1.1e-24 86.6 0.1 1.1 1 0 0 1 1 1 1 Tctex-1 family Herpes_UL4 PF03277.13 RLN31728.1 - 0.012 15.3 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL4 family Sulfate_transp PF00916.20 RLN31729.1 - 1.4e-37 129.4 23.1 2e-37 128.9 23.1 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS_2 PF13466.6 RLN31729.1 - 1.1e-07 32.1 0.7 1.1e-07 32.1 0.7 2.6 2 0 0 2 2 2 1 STAS domain STAS PF01740.21 RLN31729.1 - 0.0015 18.2 0.0 0.0034 17.0 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 RLN31729.1 - 0.041 14.3 32.2 0.022 15.2 4.1 4.5 4 1 0 4 4 4 0 Molybdate transporter of MFS superfamily Epiglycanin_C PF14654.6 RLN31729.1 - 0.14 12.2 0.2 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region TraI_2_C PF07515.11 RLN31729.1 - 0.19 11.7 0.0 0.57 10.1 0.0 1.7 2 0 0 2 2 2 0 Putative conjugal transfer nickase/helicase TraI C-term WW PF00397.26 RLN31733.1 - 4.4e-13 49.1 4.9 7.9e-13 48.2 4.9 1.4 1 0 0 1 1 1 1 WW domain Glyco_hydro_18 PF00704.28 RLN31733.1 - 0.054 13.2 0.1 0.059 13.1 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 SSF PF00474.17 RLN31734.1 - 5.6e-87 292.2 14.3 5.6e-87 292.2 14.3 1.8 2 0 0 2 2 2 1 Sodium:solute symporter family MscL PF01741.18 RLN31734.1 - 1.1 9.6 4.3 20 5.5 0.1 3.3 3 0 0 3 3 3 0 Large-conductance mechanosensitive channel, MscL zinc_ribbon_6 PF14599.6 RLN31735.1 - 1e-14 54.2 0.1 1e-14 54.2 0.1 4.9 4 3 2 6 6 6 1 Zinc-ribbon zf-CHY PF05495.12 RLN31735.1 - 1.3e-07 32.0 8.1 1.3e-07 32.0 8.1 4.9 2 1 0 2 2 2 1 CHY zinc finger zf-RING_2 PF13639.6 RLN31735.1 - 0.00037 20.8 12.3 0.00037 20.8 12.3 5.6 3 1 3 6 6 6 1 Ring finger domain CBM9_1 PF06452.11 RLN31736.1 - 1.3e-07 31.8 1.6 2.2e-07 31.0 1.6 1.4 1 0 0 1 1 1 1 Carbohydrate family 9 binding domain-like CBM9_2 PF16011.5 RLN31736.1 - 0.0019 18.0 0.5 0.0052 16.5 0.1 1.8 2 0 0 2 2 2 1 Carbohydrate-binding family 9 NOA36 PF06524.12 RLN31738.1 - 0.015 14.6 5.7 0.02 14.2 5.7 1.2 1 0 0 1 1 1 0 NOA36 protein Na_trans_assoc PF06512.13 RLN31738.1 - 0.041 14.2 3.9 0.043 14.1 3.9 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Drc1-Sld2 PF11719.8 RLN31738.1 - 0.11 12.0 4.1 0.14 11.6 4.1 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein PI3K_1B_p101 PF10486.9 RLN31738.1 - 0.47 8.2 2.5 0.47 8.2 2.5 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CDC45 PF02724.14 RLN31738.1 - 0.68 8.2 6.3 0.66 8.2 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 RLN31738.1 - 4 5.9 9.3 5 5.5 9.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4637 PF15470.6 RLN31738.1 - 6.7 6.4 9.1 10 5.8 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) S-antigen PF05756.11 RLN31738.1 - 8.8 6.8 9.3 18 5.8 9.3 1.5 1 0 0 1 1 1 0 S-antigen protein RMI1_N PF08585.12 RLN31739.1 - 0.63 9.8 7.9 2.6 7.8 0.2 2.1 2 0 0 2 2 2 0 RecQ mediated genome instability protein TEX19 PF15553.6 RLN31739.1 - 0.68 9.9 6.9 0.64 10.0 5.6 1.6 1 1 1 2 2 2 0 Testis-expressed protein 19 FAM176 PF14851.6 RLN31739.1 - 5.6 6.6 8.4 5.5 6.6 4.9 2.2 2 0 0 2 2 2 0 FAM176 family RGS PF00615.19 RLN31740.1 - 4.2e-06 27.0 0.3 5.7e-06 26.6 0.3 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain PGA_cap PF09587.10 RLN31742.1 - 2.7e-32 112.2 0.0 2.8e-26 92.5 0.0 2.2 1 1 1 2 2 2 2 Bacterial capsule synthesis protein PGA_cap ABC_tran PF00005.27 RLN31743.1 - 9.3e-45 152.5 0.0 1.4e-23 83.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 RLN31743.1 - 1.7e-43 149.2 19.3 2.6e-30 106.0 12.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 RLN31743.1 - 7.6e-10 38.6 2.9 0.024 14.1 0.6 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RLN31743.1 - 2e-07 30.6 1.2 0.0016 18.2 0.1 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN31743.1 - 1.7e-06 28.6 0.7 0.00041 20.8 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 RLN31743.1 - 6.2e-06 26.2 4.2 0.25 11.1 0.3 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 RLN31743.1 - 1.5e-05 25.0 0.2 0.12 12.5 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RLN31743.1 - 2.3e-05 24.4 0.4 0.041 13.8 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 RLN31743.1 - 2.8e-05 24.4 0.8 0.025 14.9 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 RLN31743.1 - 0.00013 22.6 1.8 0.4 11.2 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 RLN31743.1 - 0.00019 21.1 1.2 0.043 13.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 RLN31743.1 - 0.00046 19.6 1.1 0.05 12.9 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family cobW PF02492.19 RLN31743.1 - 0.0017 18.0 1.3 0.13 11.8 0.2 3.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 RLN31743.1 - 0.0027 16.8 0.1 0.047 12.7 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.6 RLN31743.1 - 0.0029 17.8 0.1 0.059 13.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RLN31743.1 - 0.0032 16.8 0.9 0.03 13.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 RLN31743.1 - 0.0043 16.6 0.1 0.34 10.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Dynamin_N PF00350.23 RLN31743.1 - 0.017 15.2 4.3 0.46 10.5 0.1 2.8 3 0 0 3 3 2 0 Dynamin family AAA_30 PF13604.6 RLN31743.1 - 0.02 14.6 1.6 0.39 10.4 0.0 2.9 3 1 0 3 3 3 0 AAA domain T6SS_VasE PF05936.12 RLN31743.1 - 0.021 13.5 0.1 0.061 12.0 0.1 1.7 2 0 0 2 2 2 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE Viral_helicase1 PF01443.18 RLN31743.1 - 0.042 13.6 0.8 5.5 6.7 0.0 3.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ATP-synt_ab PF00006.25 RLN31743.1 - 0.051 13.2 0.3 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_ATPase PF09818.9 RLN31743.1 - 0.058 12.2 0.1 0.27 10.0 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_18 PF13238.6 RLN31743.1 - 0.096 13.2 0.6 22 5.6 0.1 2.8 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.17 RLN31743.1 - 0.1 12.7 4.6 5 7.2 0.3 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain NACHT PF05729.12 RLN31743.1 - 0.1 12.5 1.6 1.3 9.0 0.1 2.9 3 0 0 3 3 3 0 NACHT domain DUF815 PF05673.13 RLN31743.1 - 0.13 11.4 0.0 11 5.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.9 RLN31743.1 - 0.2 10.5 1.3 2.2 7.1 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_15 PF13175.6 RLN31743.1 - 0.33 10.6 1.6 3.2 7.4 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 RLN31743.1 - 0.95 9.5 3.2 42 4.1 0.1 3.7 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) bZIP_2 PF07716.15 RLN31744.1 - 0.032 14.3 5.8 0.068 13.3 5.8 1.4 1 0 0 1 1 1 0 Basic region leucine zipper GvpL_GvpF PF06386.11 RLN31744.1 - 0.078 12.9 2.6 0.11 12.4 2.6 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_1 PF00170.21 RLN31744.1 - 0.078 13.1 7.8 0.12 12.5 7.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor bZIP_Maf PF03131.17 RLN31744.1 - 0.29 11.7 8.2 0.53 10.8 8.2 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor HEAT PF02985.22 RLN31745.1 - 4.3e-05 23.4 0.4 0.015 15.5 0.1 4.4 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 RLN31745.1 - 4.4e-05 23.8 0.6 0.023 15.1 0.0 4.4 4 1 0 4 4 4 1 HEAT repeats Cnd1 PF12717.7 RLN31745.1 - 0.0027 17.8 4.0 0.11 12.5 0.0 4.7 6 0 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 VHS PF00790.19 RLN31745.1 - 0.016 15.0 0.1 0.24 11.2 0.0 2.8 2 0 0 2 2 2 0 VHS domain NYD-SP28 PF14772.6 RLN31746.1 - 3.1e-12 46.4 12.3 3.1e-12 46.4 12.3 4.9 3 2 2 5 5 5 1 Sperm tail NYD-SP28_assoc PF14775.6 RLN31746.1 - 3.6e-05 23.8 2.5 3.6e-05 23.8 2.5 3.6 4 0 0 4 4 4 1 Sperm tail C-terminal domain DUF948 PF06103.11 RLN31746.1 - 5.6 7.3 8.6 6 7.2 0.3 3.5 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUSP PF06337.12 RLN31747.1 - 7.7e-14 52.1 0.0 1.6e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 DUSP domain PX PF00787.24 RLN31747.1 - 1.4e-09 38.0 0.2 6.1e-08 32.6 0.0 2.5 2 0 0 2 2 2 1 PX domain IQ PF00612.27 RLN31747.1 - 3.3e-05 23.3 13.7 0.013 15.3 0.8 4.4 3 0 0 3 3 3 2 IQ calmodulin-binding motif CLZ PF16526.5 RLN31747.1 - 0.22 11.9 8.5 0.36 11.2 1.1 3.4 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_1 PF00170.21 RLN31747.1 - 0.46 10.6 12.1 1.5 9.0 12.1 1.9 1 0 0 1 1 1 0 bZIP transcription factor TPR_7 PF13176.6 RLN31748.1 - 0.00085 19.2 0.1 0.0024 17.8 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 RLN31748.1 - 0.016 15.3 0.1 0.041 14.0 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN31748.1 - 0.051 14.2 0.6 0.18 12.5 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN31748.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat GPI-anchored PF10342.9 RLN31751.1 - 0.00082 20.1 0.0 0.0014 19.4 0.0 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3106 PF11304.8 RLN31751.1 - 0.084 13.4 0.2 0.19 12.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) COG6 PF06419.11 RLN31753.1 - 8.9e-130 433.8 0.0 4.8e-117 391.8 0.0 2.0 2 0 0 2 2 2 2 Conserved oligomeric complex COG6 CK2S PF15011.6 RLN31753.1 - 0.03 14.2 0.7 0.03 14.2 0.7 2.1 2 0 0 2 2 2 0 Casein Kinase 2 substrate ZapB PF06005.12 RLN31753.1 - 0.083 13.3 0.4 2.6 8.6 0.0 3.1 3 0 0 3 3 3 0 Cell division protein ZapB NPV_P10 PF05531.12 RLN31753.1 - 0.35 11.3 1.0 1.1 9.8 0.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein LPP PF04728.13 RLN31753.1 - 2.5 8.6 4.8 1.5 9.3 1.4 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper FlgN PF05130.12 RLN31753.1 - 3.3 8.2 9.0 0.69 10.4 3.8 2.5 3 0 0 3 3 3 0 FlgN protein Allexi_40kDa PF05549.11 RLN31754.1 - 0.013 15.1 2.5 0.018 14.6 2.5 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein TRAF_BIRC3_bd PF16673.5 RLN31754.1 - 0.03 14.1 0.8 0.07 12.9 0.5 1.8 1 1 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain BBP1_C PF15272.6 RLN31754.1 - 0.031 14.1 3.9 0.044 13.6 3.9 1.1 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal ABC_tran_CTD PF16326.5 RLN31754.1 - 0.069 13.4 2.6 0.079 13.2 0.5 2.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain COG5 PF10392.9 RLN31754.1 - 0.11 12.7 6.4 0.21 11.8 6.4 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 ADIP PF11559.8 RLN31754.1 - 0.43 10.7 10.2 0.83 9.7 10.2 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding bZIP_Maf PF03131.17 RLN31754.1 - 1.1 9.8 13.8 1.8 9.1 12.9 1.8 1 1 1 2 2 2 0 bZIP Maf transcription factor PI3_PI4_kinase PF00454.27 RLN31755.1 - 1.4e-37 129.8 0.2 1.1e-27 97.5 0.2 2.2 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 RLN31755.1 - 0.0044 16.4 0.1 0.027 13.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4135) Helitron_like_N PF14214.6 RLN31809.1 - 1e-11 45.4 0.0 3e-11 43.9 0.0 1.7 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus DDE_1 PF03184.19 RLN31811.1 - 2.3e-13 50.2 0.0 3.5e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN31811.1 - 1.9e-09 37.4 0.1 2.2e-08 34.0 0.0 2.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CLPTM1 PF05602.12 RLN31815.1 - 5.7e-100 335.3 6.5 6.9e-100 335.1 6.5 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Aa_trans PF01490.18 RLN31815.1 - 0.0028 16.4 1.0 0.55 8.9 0.0 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein TMEM208_SND2 PF05620.11 RLN31815.1 - 0.04 13.7 5.9 0.038 13.8 3.8 2.0 2 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 PQ-loop PF04193.14 RLN31815.1 - 0.047 13.5 0.8 0.047 13.5 0.8 3.2 3 1 0 3 3 3 0 PQ loop repeat IQ PF00612.27 RLN31816.1 - 0.00035 20.1 0.2 0.00097 18.7 0.2 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif ISG65-75 PF11727.8 RLN31816.1 - 0.0028 17.0 4.2 0.0028 17.0 4.2 1.9 1 1 1 2 2 2 1 Invariant surface glycoprotein FadA PF09403.10 RLN31816.1 - 5.4 7.6 12.8 1.9 9.0 2.8 3.1 3 0 0 3 3 3 0 Adhesion protein FadA LRR_6 PF13516.6 RLN31817.1 - 4.8e-14 51.1 13.9 0.048 13.7 0.0 5.9 6 0 0 6 6 6 5 Leucine Rich repeat LRR_4 PF12799.7 RLN31817.1 - 0.0003 21.1 13.2 0.45 11.0 1.0 3.6 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN31817.1 - 0.0003 20.5 10.9 0.018 14.8 6.5 4.1 2 2 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 RLN31817.1 - 0.00053 20.2 8.5 1.8 9.4 0.0 5.0 4 1 0 4 4 4 1 Leucine Rich Repeat Epimerase_2 PF02350.19 RLN31817.1 - 0.013 14.4 0.1 0.021 13.7 0.1 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase MIT PF04212.18 RLN31818.1 - 0.0013 18.8 0.6 0.0034 17.4 0.6 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF3446 PF11928.8 RLN31818.1 - 0.032 14.5 3.0 6 7.2 0.6 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain IMUP PF15761.5 RLN31818.1 - 0.09 13.5 13.1 0.12 13.1 6.9 2.6 2 0 0 2 2 2 0 Immortalisation up-regulated protein Trypsin_2 PF13365.6 RLN31820.1 - 2.6e-15 57.6 0.1 3.5e-15 57.2 0.1 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 RLN31820.1 - 4.2e-06 26.7 2.4 1.6e-05 24.9 2.4 1.8 1 1 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 RLN31820.1 - 0.0038 16.0 0.4 0.56 8.8 0.0 2.0 2 0 0 2 2 2 2 Peptidase S46 Peptidase_C4 PF00863.19 RLN31820.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C4 Pkinase_Tyr PF07714.17 RLN31821.1 - 5.4e-67 225.8 0.0 1.2e-33 116.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN31821.1 - 6.1e-60 202.8 0.0 8.9e-30 103.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 RLN31821.1 - 2.6e-05 23.7 0.0 0.014 14.7 0.0 3.0 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN31821.1 - 0.00058 19.3 0.0 0.22 10.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 RLN31821.1 - 0.0015 18.5 2.8 0.069 13.1 0.0 3.6 4 0 0 4 4 4 1 Phosphotransferase enzyme family RIO1 PF01163.22 RLN31821.1 - 0.0023 17.6 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 2 RIO1 family CarboxypepD_reg PF13620.6 RLN31822.1 - 6.8e-05 23.1 0.0 0.048 13.9 0.0 3.6 4 0 0 4 4 4 2 Carboxypeptidase regulatory-like domain YL1 PF05764.13 RLN31822.1 - 0.2 11.7 4.4 0.34 11.0 4.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein RNA_pol_Rpb1_R PF05001.13 RLN31822.1 - 0.47 10.9 16.5 0.28 11.6 4.5 3.0 1 1 0 2 2 2 0 RNA polymerase Rpb1 C-terminal repeat MtN3_slv PF03083.16 RLN31898.1 - 2.1e-26 91.7 15.4 1e-17 63.9 2.2 2.5 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RLN31898.1 - 7e-05 22.5 0.4 7e-05 22.5 0.4 3.2 4 0 0 4 4 4 1 PQ loop repeat OATP PF03137.20 RLN31898.1 - 0.00068 18.0 0.1 0.0085 14.4 0.1 2.2 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF2569 PF10754.9 RLN31898.1 - 0.13 12.7 10.7 0.93 9.9 3.5 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF2569) DUF4131 PF13567.6 RLN31898.1 - 1.7 8.2 5.1 0.23 11.1 0.5 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) ox_reductase_C PF08635.10 RLN31899.1 - 4.6e-42 143.0 0.0 6.9e-42 142.5 0.0 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 RLN31899.1 - 1.7e-16 61.1 0.0 2.8e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 RLN31899.1 - 0.00056 19.9 0.0 0.0013 18.7 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain TPR_3 PF07720.12 RLN31899.1 - 0.09 12.8 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat ox_reductase_C PF08635.10 RLN31900.1 - 4.5e-42 143.1 0.0 6.9e-42 142.5 0.0 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 RLN31900.1 - 4.5e-17 63.0 0.0 7.4e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 RLN31900.1 - 0.00055 19.9 0.0 0.0013 18.7 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain TPR_3 PF07720.12 RLN31900.1 - 0.091 12.8 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat ABC_membrane PF00664.23 RLN31902.1 - 1.6e-100 336.3 29.2 1.3e-52 179.1 4.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN31902.1 - 1.1e-68 230.0 0.0 1.3e-33 116.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN31902.1 - 1.3e-08 34.5 5.9 0.0021 17.5 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RLN31902.1 - 2.4e-08 33.6 1.3 0.0023 17.6 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN31902.1 - 1e-07 32.5 2.1 0.0092 16.4 0.5 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 RLN31902.1 - 2.3e-07 31.2 1.6 0.03 14.6 0.0 4.2 3 2 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 RLN31902.1 - 3.5e-07 29.7 0.0 0.023 14.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_15 PF13175.6 RLN31902.1 - 1.1e-05 25.3 0.0 0.055 13.2 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 RLN31902.1 - 3.2e-05 23.9 1.7 0.48 10.2 0.1 3.8 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN31902.1 - 3.3e-05 23.8 0.2 0.18 11.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 RLN31902.1 - 8.7e-05 22.3 2.1 0.51 10.0 0.1 3.3 2 2 0 2 2 2 2 AAA domain G-alpha PF00503.20 RLN31902.1 - 0.00026 20.3 0.0 0.56 9.3 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_28 PF13521.6 RLN31902.1 - 0.00029 21.1 0.3 1.4 9.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 RLN31902.1 - 0.00059 19.9 0.4 2.7 8.0 0.0 3.4 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 RLN31902.1 - 0.00076 20.0 0.0 0.98 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 RLN31902.1 - 0.00096 18.1 3.3 0.12 11.1 0.1 2.5 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 RLN31902.1 - 0.0011 18.6 1.6 1.1 8.8 0.0 3.4 4 0 0 4 4 4 1 AAA domain DUF87 PF01935.17 RLN31902.1 - 0.0019 18.3 1.6 1.9 8.6 0.1 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain APS_kinase PF01583.20 RLN31902.1 - 0.0028 17.5 0.0 3.2 7.6 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_7 PF12775.7 RLN31902.1 - 0.003 17.1 0.1 2.3 7.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 RLN31902.1 - 0.0034 17.5 0.2 4.2 7.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 RLN31902.1 - 0.0091 16.2 4.8 2.7 8.3 0.5 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 RLN31902.1 - 0.0095 16.0 0.1 6.6 6.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 RLN31902.1 - 0.01 15.5 0.0 5.3 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 RLN31902.1 - 0.011 14.9 0.0 3.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 RLN31902.1 - 0.018 14.4 0.9 5.4 6.3 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Ploopntkinase3 PF18751.1 RLN31902.1 - 0.027 14.4 0.0 10 6.0 0.0 2.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_23 PF13476.6 RLN31902.1 - 0.038 14.5 0.0 9.2 6.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 RLN31902.1 - 0.046 12.7 0.0 3.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DEAD PF00270.29 RLN31902.1 - 0.081 12.7 1.0 72 3.1 0.0 3.8 3 1 0 3 3 3 0 DEAD/DEAH box helicase ATP-synt_ab PF00006.25 RLN31902.1 - 0.1 12.3 0.0 10 5.7 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 RLN31902.1 - 0.28 11.1 3.5 15 5.5 0.0 3.3 4 0 0 4 4 4 0 NACHT domain Cauli_VI PF01693.16 RLN31906.1 - 1.4e-31 108.5 3.0 7.2e-16 58.2 0.3 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 RLN31906.1 - 8.4e-28 97.4 0.0 1.2e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 RNase H Pirin_C PF05726.13 RLN31907.1 - 5.8e-29 100.5 0.0 7e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Pirin_C_2 PF17954.1 RLN31907.1 - 0.0011 19.0 0.0 0.002 18.2 0.0 1.4 2 0 0 2 2 2 1 Quercetinase C-terminal cupin domain p450 PF00067.22 RLN31908.1 - 3.5e-19 68.9 0.0 4.3e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 C12orf66_like PF09404.10 RLN31908.1 - 0.05 12.4 0.0 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 KICSTOR complex C12orf66 like p450 PF00067.22 RLN31909.1 - 7.9e-68 229.3 0.0 1e-67 228.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SCP2_2 PF13530.6 RLN31909.1 - 0.00019 21.8 0.0 0.00042 20.7 0.0 1.6 1 0 0 1 1 1 1 Sterol carrier protein domain Dimer_Tnp_hAT PF05699.14 RLN31922.1 - 2.3e-13 49.7 0.0 5.4e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 RLN31922.1 - 0.00035 20.9 0.1 0.0027 18.1 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) Glucan_synthase PF02364.15 RLN31924.1 - 0.083 11.0 0.1 0.1 10.8 0.1 1.1 1 0 0 1 1 1 0 1,3-beta-glucan synthase component MFS_2 PF13347.6 RLN31925.1 - 0.047 12.2 18.0 0.14 10.6 17.9 2.1 1 1 0 1 1 1 0 MFS/sugar transport protein Pectate_lyase PF03211.13 RLN31926.1 - 1.5e-81 272.8 7.4 3.2e-81 271.7 7.4 1.5 1 0 0 1 1 1 1 Pectate lyase RIFIN PF02009.16 RLN31926.1 - 0.45 10.4 3.7 0.66 9.8 3.7 1.3 1 0 0 1 1 1 0 Rifin SAPS PF04499.15 RLN31926.1 - 0.8 8.4 5.5 1 8.1 5.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 RLN31926.1 - 0.93 7.5 5.3 1.1 7.3 5.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EIIBC-GUT_N PF03612.14 RLN31926.1 - 1.2 8.9 7.0 6.8 6.4 5.0 2.5 2 1 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Macoilin PF09726.9 RLN31926.1 - 4 5.9 10.6 5.4 5.5 10.6 1.1 1 0 0 1 1 1 0 Macoilin family PI3_PI4_kinase PF00454.27 RLN31927.1 - 3.2e-30 105.8 0.0 2.9e-24 86.2 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PH PF00169.29 RLN31927.1 - 2.4e-05 24.8 0.1 5e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 PH domain FYVE PF01363.21 RLN31927.1 - 0.013 15.7 15.5 0.028 14.6 15.5 1.5 1 0 0 1 1 1 0 FYVE zinc finger Pkinase_Tyr PF07714.17 RLN31939.1 - 1.7e-40 138.9 0.0 3.3e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN31939.1 - 2e-36 125.7 0.0 1.1e-35 123.3 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain DZR PF12773.7 RLN31939.1 - 0.00034 20.6 0.7 0.00082 19.3 0.7 1.6 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 RLN31939.1 - 0.00056 20.6 0.6 0.0015 19.2 0.6 1.8 1 0 0 1 1 1 1 zinc-ribbon family UPF0547 PF10571.9 RLN31939.1 - 0.0011 19.0 0.7 0.0031 17.6 0.7 1.8 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.6 RLN31939.1 - 0.0061 16.2 1.0 0.018 14.8 1.0 1.9 1 0 0 1 1 1 1 zinc-ribbon domain RIO1 PF01163.22 RLN31939.1 - 0.017 14.7 0.2 0.22 11.1 0.0 2.5 2 0 0 2 2 2 0 RIO1 family DUF2116 PF09889.9 RLN31939.1 - 0.032 14.2 0.4 0.086 12.8 0.4 1.7 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) APH PF01636.23 RLN31939.1 - 0.04 13.8 0.5 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family ABC1 PF03109.16 RLN31939.1 - 0.11 12.7 0.3 11 6.2 0.0 2.8 2 1 0 2 2 2 0 ABC1 family Zn_ribbon_17 PF17120.5 RLN31939.1 - 0.12 12.0 0.3 0.3 10.7 0.3 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Nup54 PF13874.6 RLN31939.1 - 0.4 10.8 3.5 1 9.5 3.5 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF5129 PF17173.4 RLN31939.1 - 0.68 9.0 4.5 1.2 8.1 4.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5129) zf-ribbon_3 PF13248.6 RLN31939.1 - 0.76 9.3 5.2 0.2 11.1 0.9 2.2 2 0 0 2 2 2 0 zinc-ribbon domain FlgN PF05130.12 RLN31939.1 - 1.4 9.4 9.8 7 7.1 2.7 2.5 3 0 0 3 3 2 0 FlgN protein DUF148 PF02520.17 RLN31939.1 - 2.2 8.4 9.6 9.2 6.4 1.5 3.5 3 1 1 4 4 4 0 Domain of unknown function DUF148 CorA PF01544.18 RLN31940.1 - 3.7e-55 187.3 0.7 4.5e-45 154.2 0.6 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein CENP-Q PF13094.6 RLN31940.1 - 0.032 14.5 0.3 3.5 7.8 0.1 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit EF-hand_7 PF13499.6 RLN31940.1 - 0.095 13.2 0.1 0.31 11.5 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain pair Zw10 PF06248.13 RLN31941.1 - 3.6e-43 148.0 5.9 5.8e-25 87.9 0.0 2.4 2 1 0 2 2 2 2 Centromere/kinetochore Zw10 Exo84_C PF16528.5 RLN31941.1 - 0.012 15.4 0.1 0.03 14.1 0.1 1.6 1 0 0 1 1 1 0 Exocyst component 84 C-terminal LisH_TPL PF17814.1 RLN31942.1 - 1.6e-13 50.0 0.0 2.6e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 LisH-like dimerisation domain LisH PF08513.11 RLN31942.1 - 0.025 14.5 0.2 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 LisH Acetyltransf_5 PF13444.6 RLN31942.1 - 0.13 13.0 0.0 0.14 12.8 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Asp_protease PF09668.10 RLN31943.1 - 3e-15 56.1 0.0 5.1e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DnaJ PF00226.31 RLN31943.1 - 5.8e-14 52.0 0.5 1.3e-13 50.9 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain UBA PF00627.31 RLN31943.1 - 5.7e-07 29.3 0.2 0.023 14.6 0.0 2.4 2 0 0 2 2 2 2 UBA/TS-N domain gag-asp_proteas PF13975.6 RLN31943.1 - 6.1e-07 29.9 0.0 2.7e-06 27.8 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 RLN31943.1 - 0.0018 18.8 0.0 0.0064 17.1 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease DUF4523 PF15023.6 RLN31943.1 - 0.011 15.5 0.1 0.022 14.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) RVP PF00077.20 RLN31943.1 - 0.022 15.1 0.0 0.054 13.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease UBA_4 PF14555.6 RLN31943.1 - 0.048 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain DUF4407 PF14362.6 RLN31943.1 - 7.6 5.8 9.9 12 5.1 9.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C3HC4_2 PF13923.6 RLN31953.1 - 1.9e-06 27.6 2.0 1.9e-06 27.6 2.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN31953.1 - 4.7e-06 26.5 1.1 1.5e-05 24.8 0.4 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 RLN31953.1 - 8.6e-06 26.0 2.0 1.5e-05 25.2 0.4 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 RLN31953.1 - 1.1e-05 25.6 1.2 1.1e-05 25.6 1.2 2.3 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 RLN31953.1 - 6.4e-05 22.7 1.6 0.0001 22.1 0.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN31953.1 - 0.00078 19.3 1.4 0.0026 17.6 0.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN31953.1 - 0.0048 16.6 0.3 0.016 14.9 0.3 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 RLN31953.1 - 0.0056 16.7 0.5 0.016 15.2 0.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 RLN31953.1 - 0.038 13.9 2.6 0.038 13.9 0.6 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 RLN31953.1 - 0.046 13.8 0.8 0.13 12.4 0.1 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.14 RLN31953.1 - 0.23 11.3 0.9 11 5.9 0.1 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif PHD PF00628.29 RLN31953.1 - 1.3 9.0 4.5 0.44 10.5 1.3 1.9 2 0 0 2 2 2 0 PHD-finger zf-C3HC4_2 PF13923.6 RLN31954.1 - 4.2e-07 29.7 2.0 4.2e-07 29.7 2.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN31954.1 - 3.6e-05 24.0 1.7 3.6e-05 24.0 1.7 2.4 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 RLN31954.1 - 4.2e-05 23.7 5.8 0.00031 21.0 5.8 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RLN31954.1 - 9.6e-05 22.3 0.9 9.6e-05 22.3 0.9 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RLN31954.1 - 0.00024 20.9 4.6 0.00071 19.4 4.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN31954.1 - 0.0026 17.4 0.4 0.0089 15.8 0.4 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 RLN31954.1 - 0.003 17.6 1.2 0.011 15.7 0.6 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RLN31954.1 - 0.0069 16.2 1.5 0.029 14.2 0.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN31954.1 - 0.019 14.8 2.3 0.069 13.0 1.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 RLN31954.1 - 0.16 12.2 4.6 0.086 13.0 1.8 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 RLN31954.1 - 0.18 11.9 1.4 0.58 10.2 0.5 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn-ribbon_8 PF09723.10 RLN31954.1 - 2.2 8.4 5.7 0.93 9.7 1.5 2.3 2 0 0 2 2 2 0 Zinc ribbon domain RAP1 PF07218.11 RLN31954.1 - 8.2 4.6 6.1 10 4.3 6.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Kinesin PF00225.23 RLN31955.1 - 6.1e-92 308.1 0.0 1.2e-91 307.1 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN31955.1 - 5e-24 84.9 0.1 1.9e-21 76.5 0.0 2.4 2 0 0 2 2 2 2 Microtubule binding HTH_23 PF13384.6 RLN31956.1 - 4.2e-05 23.2 0.4 7e-05 22.5 0.4 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 RLN31956.1 - 0.004 17.2 0.3 0.0076 16.4 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 RLN31956.1 - 0.0063 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase CENP-B_N PF04218.13 RLN31956.1 - 0.007 16.0 0.6 0.01 15.4 0.6 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain YdaS_antitoxin PF15943.5 RLN31956.1 - 0.029 14.2 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_Tnp_4 PF13613.6 RLN31956.1 - 0.03 14.0 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease FAM163 PF15069.6 RLN31987.1 - 0.0017 18.8 0.0 0.0023 18.4 0.0 1.3 1 0 0 1 1 1 1 FAM163 family zinc-ribbons_6 PF07191.12 RLN31987.1 - 0.056 13.4 0.9 0.056 13.4 0.9 1.5 2 0 0 2 2 2 0 zinc-ribbons Tnp_zf-ribbon_2 PF13842.6 RLN31987.1 - 0.33 11.8 5.4 0.64 10.9 5.4 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon LRR_8 PF13855.6 RLN31991.1 - 1.7e-05 24.5 0.2 0.62 9.9 0.0 4.7 4 2 1 5 5 5 2 Leucine rich repeat Thump_like PF18096.1 RLN31991.1 - 0.028 14.4 0.0 3.2 7.7 0.0 2.4 2 0 0 2 2 2 0 THUMP domain-like LRR_4 PF12799.7 RLN31991.1 - 0.045 14.2 1.1 1.4 9.5 0.4 3.5 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) SyrA PF11089.8 RLN31992.1 - 0.011 15.8 2.2 0.038 14.1 2.2 1.9 1 0 0 1 1 1 0 Exopolysaccharide production repressor ORC4_C PF14629.6 RLN31993.1 - 5.3e-15 55.4 0.1 8e-15 54.8 0.1 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 RLN31993.1 - 1e-06 29.2 0.2 1e-06 29.2 0.2 2.3 3 1 0 3 3 3 1 AAA ATPase domain ATPase_2 PF01637.18 RLN31993.1 - 0.00037 20.5 0.0 0.00062 19.8 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 RLN31993.1 - 0.0039 17.6 0.0 0.0088 16.5 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Diphthamide_syn PF01866.17 RLN31993.1 - 0.078 12.4 0.2 13 5.1 0.0 2.8 3 0 0 3 3 3 0 Putative diphthamide synthesis protein DUF296 PF03479.15 RLN31993.1 - 0.12 12.7 0.1 0.38 11.1 0.0 1.9 2 0 0 2 2 2 0 Plants and Prokaryotes Conserved (PCC) domain LRR_8 PF13855.6 RLN31994.1 - 0.0027 17.4 4.4 0.29 10.9 0.3 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 RLN31994.1 - 0.015 15.7 3.2 0.15 12.5 0.2 3.2 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) DUF4205 PF13898.6 RLN31995.1 - 3.9e-64 216.8 0.0 1.8e-58 198.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4205) DUF2807 PF10988.8 RLN32001.1 - 5.6e-14 52.3 9.4 2e-10 40.8 2.6 2.2 1 1 1 2 2 2 2 Putative auto-transporter adhesin, head GIN domain DUF4079 PF13301.6 RLN32001.1 - 2.1 8.5 4.6 0.75 9.9 0.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4079) TauD PF02668.16 RLN32002.1 - 2.7e-58 197.9 4.0 1.6e-56 192.1 4.0 2.1 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3746 PF12562.8 RLN32002.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3746) PTR2 PF00854.21 RLN32003.1 - 3.5e-37 128.2 8.3 3.5e-37 128.2 8.3 1.8 2 1 0 2 2 2 1 POT family DUF872 PF05915.12 RLN32003.1 - 1.5 9.0 8.1 4.9 7.4 0.1 3.3 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) TauD PF02668.16 RLN32004.1 - 1.3e-45 156.3 5.8 1.3e-36 126.7 0.5 2.1 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family PTR2 PF00854.21 RLN32005.1 - 2.7e-38 131.8 11.4 5.1e-38 130.9 11.4 1.4 1 0 0 1 1 1 1 POT family peroxidase PF00141.23 RLN32011.1 - 4.1e-75 252.4 0.0 8.3e-47 159.8 0.0 2.8 2 1 0 2 2 2 2 Peroxidase TMEM51 PF15345.6 RLN32012.1 - 0.0013 18.7 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 Herpes_gE PF02480.16 RLN32012.1 - 0.04 12.7 0.0 0.05 12.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E NUDE_C PF04880.13 RLN32012.1 - 2.1 8.8 5.2 4.9 7.6 5.2 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region CcmD PF04995.14 RLN32012.1 - 4.1 7.6 6.7 0.77 9.9 1.3 2.2 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) GST_C_3 PF14497.6 RLN32013.1 - 3.2e-10 40.1 0.0 5.2e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RLN32013.1 - 3.8e-08 33.6 0.0 7.1e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 RLN32013.1 - 0.00017 21.9 0.0 0.00026 21.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RLN32013.1 - 0.0004 20.6 0.1 0.00084 19.5 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RLN32013.1 - 0.00059 20.1 0.0 0.00094 19.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN32013.1 - 0.0086 16.1 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 RLN32013.1 - 0.099 13.4 0.0 0.21 12.4 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain Beach PF02138.18 RLN32014.1 - 4.6e-109 364.1 0.0 7.4e-109 363.4 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 RLN32014.1 - 2e-14 53.5 0.1 7.3e-14 51.7 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 RLN32014.1 - 2.5e-14 53.2 0.1 5.1e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 RLN32014.1 - 1.4e-05 25.3 0.0 4.4e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 RLN32014.1 - 0.0042 17.9 3.8 0.086 13.7 0.1 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat SOSSC PF15925.5 RLN32014.1 - 0.064 14.6 0.2 0.27 12.6 0.0 2.3 2 0 0 2 2 2 0 SOSS complex subunit C Dickkopf_N PF04706.12 RLN32015.1 - 0.44 11.1 8.4 0.67 10.5 0.4 2.5 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region EcKinase PF02958.20 RLN32020.1 - 5.9e-17 61.9 0.0 6.5e-16 58.5 0.0 2.1 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 RLN32020.1 - 2.2e-13 49.9 0.0 1.3e-12 47.4 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 RLN32020.1 - 6.4e-11 42.6 0.1 9.1e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN32020.1 - 0.15 11.4 0.1 2.5 7.4 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family TRAM_LAG1_CLN8 PF03798.16 RLN32021.1 - 2.2e-29 102.6 15.4 3.3e-29 102.1 15.4 1.2 1 0 0 1 1 1 1 TLC domain LRR_6 PF13516.6 RLN32022.1 - 4.7e-05 23.1 0.3 1.9 8.7 0.1 4.8 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.7 RLN32022.1 - 0.00014 22.2 4.7 1 9.9 0.1 4.4 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN32022.1 - 0.13 12.9 0.1 1.5e+02 3.6 0.1 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.6 RLN32022.1 - 0.32 10.8 9.8 8.9 6.2 0.6 4.6 2 1 2 4 4 4 0 Leucine rich repeat MutS_V PF00488.21 RLN32023.1 - 6.7e-75 251.3 0.0 1.5e-74 250.2 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 RLN32023.1 - 4.6e-34 118.3 0.1 4.6e-34 118.3 0.1 2.4 2 1 1 3 3 3 1 MutS domain III MutS_I PF01624.20 RLN32023.1 - 8.6e-29 100.1 0.1 1.9e-28 99.0 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 RLN32023.1 - 4.8e-16 58.9 1.4 9.7e-16 57.9 0.2 2.3 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 RLN32023.1 - 7.9e-10 39.1 0.2 6.1e-09 36.3 0.0 2.7 3 1 0 3 3 3 1 MutS domain II YL1 PF05764.13 RLN32023.1 - 0.00068 19.8 10.9 0.00068 19.8 10.9 3.2 4 0 0 4 4 4 1 YL1 nuclear protein AAA_29 PF13555.6 RLN32023.1 - 0.058 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L22 PF00237.19 RLN32024.1 - 1.4e-36 124.9 0.1 3.2e-36 123.7 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DEK_C PF08766.11 RLN32024.1 - 1.2e-05 25.1 0.1 3.1e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 DEK C terminal domain CHZ PF09649.10 RLN32024.1 - 9.2e-05 21.8 0.2 0.00032 20.1 0.2 2.0 1 0 0 1 1 1 1 Histone chaperone domain CHZ Shugoshin_C PF07557.11 RLN32024.1 - 0.0049 16.6 0.8 0.0049 16.6 0.8 2.5 2 0 0 2 2 2 1 Shugoshin C terminus DUF5639 PF18690.1 RLN32024.1 - 0.14 12.4 0.7 2.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5639) SURF2 PF05477.11 RLN32024.1 - 7.4 6.2 13.1 0.36 10.5 5.7 2.2 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.14 RLN32024.1 - 9.9 4.3 15.9 2.4 6.4 9.2 2.1 2 0 0 2 2 2 0 CDC45-like protein Tannase PF07519.11 RLN32027.1 - 2.2e-109 366.5 0.0 3.2e-109 365.9 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 RLN32027.1 - 4.4e-05 23.0 0.9 0.047 13.1 0.0 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family CCT PF06203.14 RLN32039.1 - 2.1e-16 59.7 14.8 4.2e-16 58.7 14.8 1.5 1 0 0 1 1 1 1 CCT motif CCT_2 PF09425.10 RLN32039.1 - 0.07 13.0 4.8 0.2 11.6 4.8 1.8 1 0 0 1 1 1 0 Divergent CCT motif DUF3678 PF12435.8 RLN32039.1 - 1.2 8.5 7.6 0.51 9.8 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Gpi16 PF04113.14 RLN32040.1 - 5.3e-109 365.2 0.1 6.4e-107 358.3 0.1 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component WD40 PF00400.32 RLN32063.1 - 2.4e-06 28.1 10.1 0.001 19.9 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF2917 PF11142.8 RLN32063.1 - 0.0049 16.2 0.1 1.1 8.7 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2917) Mito_carr PF00153.27 RLN32064.1 - 3.8e-69 228.7 1.0 1.5e-23 82.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 RLN32064.1 - 0.047 12.9 0.4 0.82 8.8 0.2 2.7 1 1 0 2 2 2 0 Gammaproteobacterial serine protease DUF5366 PF17328.2 RLN32064.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5366) Ank_2 PF12796.7 RLN32065.1 - 2.9e-12 47.0 0.1 6.9e-12 45.8 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN32065.1 - 5.1e-12 46.1 1.6 1.5e-07 31.8 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN32065.1 - 9.8e-06 25.6 0.0 0.0068 16.8 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 RLN32065.1 - 5.3e-05 23.5 0.0 0.0034 17.7 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 RLN32065.1 - 8.8e-05 22.7 0.0 0.0018 18.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Surfac_D-trimer PF09006.11 RLN32065.1 - 0.85 9.6 4.1 0.8 9.6 0.2 3.1 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation Aminotran_5 PF00266.19 RLN32066.1 - 6.2e-29 101.1 0.0 8.5e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V RnlB_antitoxin PF15933.5 RLN32066.1 - 0.077 13.3 0.0 4.1 7.8 0.0 2.5 2 0 0 2 2 2 0 Antitoxin to bacterial toxin RNase LS or RnlA DUF1152 PF06626.12 RLN32066.1 - 0.083 12.1 0.2 0.19 10.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1152) Pep_deformylase PF01327.21 RLN32067.1 - 1.2e-35 122.5 0.0 1.6e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase Tub PF01167.18 RLN32068.1 - 7.7e-71 238.6 0.0 1e-70 238.3 0.0 1.1 1 0 0 1 1 1 1 Tub family zf-RING_2 PF13639.6 RLN32068.1 - 4e-09 36.7 4.3 4e-09 36.7 4.3 1.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 RLN32068.1 - 3.1e-05 24.2 4.4 8.6e-05 22.8 4.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain RINGv PF12906.7 RLN32068.1 - 0.00025 21.1 3.8 0.0005 20.1 3.8 1.5 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4_2 PF13923.6 RLN32068.1 - 0.00025 20.8 4.3 0.00075 19.3 4.3 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF3527 PF12043.8 RLN32068.1 - 0.00038 20.1 0.0 0.001 18.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3527) zf-ANAPC11 PF12861.7 RLN32068.1 - 0.013 15.5 1.8 0.05 13.6 1.8 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RLN32068.1 - 0.017 14.9 5.1 0.042 13.7 5.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN32068.1 - 0.039 13.9 3.0 0.093 12.7 3.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 RLN32068.1 - 0.94 9.3 5.8 0.34 10.7 1.3 2.5 2 1 0 2 2 2 0 RING-like zinc finger SesA PF17107.5 RLN32073.1 - 0.14 12.3 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Ion_trans PF00520.31 RLN32075.1 - 9.5e-12 44.7 3.6 1.8e-11 43.8 3.6 1.4 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 RLN32075.1 - 3.5e-11 43.0 0.0 6.5e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain RNA_pol_Rpc4 PF05132.14 RLN32077.1 - 7.2e-27 94.6 0.0 9.9e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III RPC4 HMG_box PF00505.19 RLN32078.1 - 5.8e-43 145.2 10.8 6.1e-22 77.8 1.4 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 RLN32078.1 - 3.1e-27 95.0 10.6 3.2e-13 50.1 1.9 2.2 2 0 0 2 2 2 2 HMG-box domain CHDNT PF08073.12 RLN32078.1 - 3.5e-05 23.7 0.0 0.019 14.9 0.0 2.4 2 0 0 2 2 2 2 CHDNT (NUC034) domain Ccdc124 PF06244.12 RLN32078.1 - 0.0079 16.7 14.0 0.025 15.2 0.6 3.1 1 1 2 3 3 3 2 Coiled-coil domain-containing protein 124 /Oxs1 DUF4838 PF16126.5 RLN32078.1 - 0.02 14.3 0.3 1 8.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4838) HD-ZIP_N PF04618.12 RLN32078.1 - 0.16 12.5 0.4 0.41 11.2 0.4 1.7 1 1 0 1 1 1 0 HD-ZIP protein N terminus CNDH2_C PF16858.5 RLN32078.1 - 3.1 7.6 12.8 0.57 10.0 3.8 2.0 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term zf-CCCH PF00642.24 RLN32079.1 - 7.1e-05 22.6 4.3 7.1e-05 22.6 4.3 2.2 1 1 1 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 RLN32079.1 - 0.0074 16.1 2.2 0.0074 16.1 2.2 2.5 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 RLN32079.1 - 0.021 14.9 2.5 0.021 14.9 2.5 2.9 3 0 0 3 3 3 0 Zinc finger domain Torus PF16131.5 RLN32079.1 - 0.21 12.3 9.8 0.25 12.1 7.6 2.2 1 1 0 1 1 1 0 Torus domain Myb_DNA-binding PF00249.31 RLN32080.1 - 1.1e-39 134.4 9.4 7.1e-13 48.5 0.7 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN32080.1 - 6.7e-35 119.1 2.2 2.4e-14 53.3 0.0 3.1 1 1 2 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 RLN32080.1 - 0.00062 20.0 5.4 2 8.8 0.3 3.2 3 0 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 RLN32080.1 - 0.0034 17.5 3.6 2.3 8.4 0.4 3.1 1 1 2 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 RLN32080.1 - 0.0044 17.4 4.8 0.84 10.1 0.7 2.8 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 RLN32080.1 - 0.021 15.0 0.8 7.4 6.8 0.0 3.5 3 2 0 3 3 3 0 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 RLN32080.1 - 0.11 12.3 0.0 0.53 10.2 0.0 2.1 3 0 0 3 3 3 0 Myb DNA-binding like SLIDE PF09111.10 RLN32080.1 - 0.19 11.7 0.0 12 6.0 0.0 2.6 2 1 0 2 2 2 0 SLIDE Aldolase_II PF00596.21 RLN32081.1 - 1.3e-37 129.6 0.2 2.3e-37 128.7 0.2 1.4 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Hydrolase PF00702.26 RLN32081.1 - 3.3e-05 24.3 1.0 7.3e-05 23.1 0.2 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 RLN32081.1 - 0.00021 21.5 0.0 0.00037 20.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase ARD PF03079.14 RLN32081.1 - 0.04 14.1 0.0 0.08 13.1 0.0 1.4 1 0 0 1 1 1 0 ARD/ARD' family IFT57 PF10498.9 RLN32082.1 - 2.8e-87 293.0 0.0 3.2e-87 292.8 0.0 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Arb1 PF09692.10 RLN32082.1 - 0.019 14.1 0.1 0.025 13.7 0.1 1.1 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 OmpH PF03938.14 RLN32082.1 - 0.37 11.1 3.4 0.82 10.0 3.4 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) 2OG-FeII_Oxy_3 PF13640.6 RLN32085.1 - 5.2e-08 33.7 0.0 0.0007 20.4 0.0 2.8 3 0 0 3 3 3 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 RLN32086.1 - 0.00068 20.5 0.0 0.0013 19.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 RLN32086.1 - 0.037 14.5 0.0 0.084 13.4 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF4586 PF15239.6 RLN32087.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4586) DUF5575 PF17738.1 RLN32094.1 - 0.0025 16.9 0.0 0.0045 16.1 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5575) MULE PF10551.9 RLN32094.1 - 0.0051 17.2 0.1 0.015 15.7 0.1 1.9 1 0 0 1 1 1 1 MULE transposase domain Chal_sti_synt_N PF00195.19 RLN32094.1 - 0.058 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Peptidase_C48 PF02902.19 RLN32096.1 - 2.7e-10 40.5 0.0 4.3e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Mg_trans_NIPA PF05653.14 RLN32098.1 - 6e-23 81.4 15.6 4e-22 78.7 15.6 1.9 1 1 0 1 1 1 1 Magnesium transporter NIPA DUF2807 PF10988.8 RLN32098.1 - 4.6e-07 29.8 3.0 7e-06 26.0 3.0 2.3 1 1 0 1 1 1 1 Putative auto-transporter adhesin, head GIN domain EamA PF00892.20 RLN32098.1 - 0.012 15.7 7.7 0.012 15.7 7.7 3.0 3 1 0 3 3 3 0 EamA-like transporter family DUF1634 PF07843.11 RLN32098.1 - 0.023 14.8 1.9 0.53 10.4 2.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) TMEM234 PF10639.9 RLN32098.1 - 0.031 14.3 0.2 0.092 12.8 0.2 1.9 1 0 0 1 1 1 0 Putative transmembrane family 234 Ank_2 PF12796.7 RLN32100.1 - 1.4e-32 112.2 0.7 2.7e-05 24.7 0.0 7.6 4 3 4 8 8 8 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN32100.1 - 9.4e-19 67.2 16.5 0.0025 18.1 0.1 10.1 9 1 1 10 10 10 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN32100.1 - 1.1e-13 51.3 13.5 0.0057 17.2 0.1 8.9 5 2 5 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN32100.1 - 1.1e-10 40.8 17.7 0.5 11.1 0.0 12.7 13 0 0 13 13 13 1 Ankyrin repeat Ank PF00023.30 RLN32100.1 - 7.5e-10 38.8 32.6 1.1 9.8 0.1 11.6 12 0 0 12 12 12 5 Ankyrin repeat Ribosomal_S3Ae PF01015.18 RLN32101.1 - 3.4e-91 304.3 3.3 4e-91 304.1 3.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 RLN32101.1 - 0.19 11.3 0.0 0.39 10.3 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region AROS PF15684.5 RLN32102.1 - 0.0063 17.1 5.0 0.0086 16.6 5.0 1.2 1 0 0 1 1 1 1 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 XRN_N PF03159.18 RLN32102.1 - 0.065 12.7 1.2 0.085 12.3 1.2 1.1 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus BEX PF04538.12 RLN32102.1 - 0.14 12.8 4.1 0.18 12.4 4.1 1.2 1 0 0 1 1 1 0 Brain expressed X-linked like family SNARE PF05739.19 RLN32102.1 - 0.26 11.3 0.2 0.26 11.3 0.2 2.0 2 1 0 2 2 2 0 SNARE domain LRR_6 PF13516.6 RLN32103.1 - 4e-26 88.8 19.6 2.3e-05 24.1 0.4 9.2 9 0 0 9 9 9 7 Leucine Rich repeat LRR_4 PF12799.7 RLN32103.1 - 3.2e-11 43.3 2.8 0.057 13.9 0.0 5.2 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) PGM_PMM_IV PF00408.20 RLN32103.1 - 7.3e-10 38.9 0.1 1.9e-09 37.5 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_I PF02878.16 RLN32103.1 - 2.6e-07 30.4 0.0 2.1e-05 24.3 0.0 2.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 RLN32103.1 - 5e-07 29.9 0.1 1.4e-06 28.5 0.1 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III LRR_1 PF00560.33 RLN32103.1 - 6.8e-06 25.9 1.8 27 5.8 0.0 7.2 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.6 RLN32103.1 - 7.5e-06 25.6 12.9 0.16 11.7 0.3 5.0 3 1 2 5 5 5 4 Leucine rich repeat PGM_PMM_II PF02879.16 RLN32103.1 - 0.013 16.1 0.0 0.043 14.4 0.0 2.0 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II CAP_GLY PF01302.25 RLN32104.1 - 2.3e-23 82.0 2.0 3.6e-23 81.3 2.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain CLASP_N PF12348.8 RLN32104.1 - 5e-22 78.6 0.2 8.6e-22 77.8 0.2 1.4 1 0 0 1 1 1 1 CLASP N terminal Ysc84 PF04366.12 RLN32105.1 - 2.4e-33 114.6 0.3 4e-33 113.9 0.3 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator FYVE PF01363.21 RLN32105.1 - 0.007 16.5 0.8 0.007 16.5 0.8 3.3 3 0 0 3 3 3 1 FYVE zinc finger zf-ribbon_3 PF13248.6 RLN32105.1 - 0.02 14.3 2.2 0.02 14.3 2.2 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 RLN32105.1 - 4.2 7.1 12.9 3.3 7.4 0.8 3.8 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain SBF PF01758.16 RLN32106.1 - 7.5e-43 146.5 2.2 7.5e-43 146.5 2.2 1.6 2 0 0 2 2 2 1 Sodium Bile acid symporter family OST3_OST6 PF04756.13 RLN32107.1 - 3.9e-14 52.7 3.9 9.3e-13 48.2 3.8 2.1 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family DUF2516 PF10724.9 RLN32107.1 - 0.36 11.1 3.9 1.8 8.9 3.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2516) FYVE PF01363.21 RLN32108.1 - 0.0019 18.3 8.3 0.048 13.8 0.3 3.6 3 1 0 3 3 3 1 FYVE zinc finger zinc_ribbon_2 PF13240.6 RLN32108.1 - 0.0099 15.6 5.2 0.92 9.3 0.7 2.9 2 0 0 2 2 2 2 zinc-ribbon domain zf-ribbon_3 PF13248.6 RLN32108.1 - 0.019 14.3 1.9 0.019 14.3 1.9 2.2 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.9 RLN32108.1 - 0.71 10.0 6.1 13 6.0 0.9 3.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-NADH-PPase PF09297.11 RLN32108.1 - 1.6 8.4 9.9 5.3 6.8 0.6 3.3 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain RNA_POL_M_15KD PF02150.16 RLN32108.1 - 2.4 8.1 7.3 9.3 6.2 0.2 3.0 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit DZR PF12773.7 RLN32108.1 - 4 7.5 14.1 2.2e+02 1.9 11.2 3.5 2 1 0 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 RLN32108.1 - 4.4 6.9 6.4 9.1 5.9 4.3 2.6 2 1 0 2 2 2 0 TFIIB zinc-binding zf_UBZ PF18439.1 RLN32108.1 - 7.3 6.3 7.9 11 5.7 0.0 3.6 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Peptidase_M20 PF01546.28 RLN32111.1 - 8e-07 29.0 0.0 8.5e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF659 PF04937.15 RLN32112.1 - 1.9e-07 31.0 0.0 2.7e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) M20_dimer PF07687.14 RLN32113.1 - 1.4e-05 24.9 0.0 1.8e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 RLN32115.1 - 7e-12 45.5 0.4 1.2e-10 41.5 0.1 2.2 1 1 1 2 2 2 2 Peptidase family M20/M25/M40 M20_dimer PF07687.14 RLN32115.1 - 0.00018 21.4 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain RVT_1 PF00078.27 RLN32116.1 - 0.0093 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4457 PF14652.6 RLN32117.1 - 3.1e-66 223.9 0.0 4.9e-36 124.6 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4457) C2 PF00168.30 RLN32134.1 - 6.2e-55 183.8 0.0 1.6e-12 47.6 0.0 6.4 7 0 0 7 7 7 5 C2 domain Ferlin_C PF16165.5 RLN32134.1 - 0.0014 18.6 0.2 0.0039 17.1 0.0 1.8 2 0 0 2 2 2 1 Ferlin C-terminus FerI PF08151.12 RLN32134.1 - 0.0052 16.9 0.0 0.024 14.7 0.0 2.1 2 0 0 2 2 2 1 FerI (NUC094) domain DUF3391 PF11871.8 RLN32134.1 - 5.7 7.5 9.7 0.39 11.3 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) Pkinase_Tyr PF07714.17 RLN32135.1 - 2.9e-41 141.5 0.0 3.7e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN32135.1 - 5.6e-39 134.1 0.0 8.7e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Synaptobrevin PF00957.21 RLN32136.1 - 2.5e-24 84.9 3.6 4e-24 84.2 2.7 1.9 2 0 0 2 2 2 1 Synaptobrevin SHNi-TPR PF10516.9 RLN32136.1 - 1.4e-10 40.5 0.1 3.5e-10 39.2 0.1 1.8 1 0 0 1 1 1 1 SHNi-TPR TPR_8 PF13181.6 RLN32136.1 - 4.7e-06 26.4 0.4 0.0042 17.2 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Longin PF13774.6 RLN32136.1 - 1.9e-05 24.6 0.0 0.00016 21.6 0.0 2.3 2 0 0 2 2 2 1 Regulated-SNARE-like domain TPR_2 PF07719.17 RLN32136.1 - 3.3e-05 23.7 0.2 0.22 11.7 0.2 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN32136.1 - 0.00044 20.0 0.0 0.32 10.9 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN32136.1 - 0.0062 16.8 6.6 0.52 10.6 0.2 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN32136.1 - 0.17 11.8 3.6 1.6 8.7 0.9 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat MIF4G_like_2 PF09090.11 RLN32137.1 - 9.7e-30 103.9 0.0 2.5e-29 102.6 0.0 1.6 2 0 0 2 2 2 1 MIF4G like MIF4G_like PF09088.11 RLN32137.1 - 8.1e-27 94.2 0.1 1.8e-26 93.1 0.1 1.6 1 0 0 1 1 1 1 MIF4G like ADH_zinc_N PF00107.26 RLN32138.1 - 2.2e-15 56.8 0.0 3.4e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN32138.1 - 2.6e-13 49.8 0.9 5.3e-13 48.8 0.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 RLN32138.1 - 0.00027 20.3 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 RLN32138.1 - 0.00063 20.8 0.0 0.001 20.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 RLN32138.1 - 0.0056 16.0 0.0 0.0099 15.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glyco_transf_41 PF13844.6 RLN32139.1 - 6e-78 262.4 0.0 1.1e-46 159.3 0.0 2.3 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_17 PF13431.6 RLN32139.1 - 4.3e-19 67.5 9.5 0.0049 17.2 0.0 8.0 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 RLN32139.1 - 1.8e-17 62.0 24.4 0.0017 18.4 0.9 10.9 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_8 PF13181.6 RLN32139.1 - 4e-16 57.8 2.5 0.0089 16.2 0.0 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN32139.1 - 4.8e-16 57.8 12.9 0.0037 17.0 0.5 10.2 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_16 PF13432.6 RLN32139.1 - 8.9e-16 58.3 35.0 2.5e-05 24.8 0.0 7.3 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 RLN32139.1 - 5.4e-15 55.7 26.8 1.2e-05 25.7 0.0 7.4 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 RLN32139.1 - 2.3e-12 46.6 36.6 0.0049 17.6 0.5 11.1 4 2 6 10 10 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN32139.1 - 1.7e-11 43.6 14.4 0.0032 17.1 0.0 8.4 7 1 1 8 8 8 4 TPR repeat TPR_12 PF13424.6 RLN32139.1 - 4.1e-11 43.0 38.7 0.011 16.0 8.3 7.7 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 RLN32139.1 - 8.1e-08 31.8 18.8 1.9 8.7 0.0 7.8 8 0 0 8 8 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN32139.1 - 4.4e-07 30.0 7.1 0.00081 19.6 0.4 4.2 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 RLN32139.1 - 3.3e-06 26.8 36.4 0.093 12.6 0.0 8.6 10 0 0 10 10 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 RLN32139.1 - 1.9e-05 24.7 18.4 0.0062 16.7 0.0 6.1 5 1 2 7 7 6 2 Tetratricopeptide repeat Glyco_trans_1_4 PF13692.6 RLN32139.1 - 7.5e-05 23.2 0.0 0.00044 20.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 TPR_6 PF13174.6 RLN32139.1 - 0.0011 19.5 13.0 12 6.8 0.0 8.1 9 0 0 9 9 7 0 Tetratricopeptide repeat Glycos_transf_1 PF00534.20 RLN32139.1 - 0.0086 15.6 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 HrpB1_HrpK PF09613.10 RLN32139.1 - 0.027 14.1 0.7 7.9 6.1 0.1 4.1 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) TPPII_N PF12583.8 RLN32139.1 - 0.044 14.4 0.7 9.4 6.8 0.1 2.8 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal RPN7 PF10602.9 RLN32139.1 - 0.11 12.2 0.1 4.6 6.9 0.0 2.7 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Rapsyn_N PF10579.9 RLN32139.1 - 0.15 12.1 0.0 1.7 8.8 0.0 2.9 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region BTAD PF03704.17 RLN32139.1 - 0.55 10.6 15.7 0.025 15.0 3.8 3.7 4 0 0 4 4 3 0 Bacterial transcriptional activator domain TPR_20 PF14561.6 RLN32139.1 - 3.3 8.1 17.3 1.6 9.1 0.1 6.0 5 2 1 6 6 6 0 Tetratricopeptide repeat FSH1 PF03959.13 RLN32140.1 - 2.3e-83 279.0 0.0 3.2e-47 160.9 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 RLN32140.1 - 6.5e-07 28.9 0.8 0.24 10.6 0.0 4.3 3 2 1 5 5 5 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN32140.1 - 8.3e-07 29.8 0.5 0.042 14.5 0.0 3.7 2 2 1 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 RLN32140.1 - 4.7e-05 23.3 1.4 0.91 9.3 0.7 4.5 4 1 0 5 5 5 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 RLN32140.1 - 0.00054 19.5 0.7 0.54 9.7 0.1 3.7 3 1 0 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.18 RLN32140.1 - 0.00061 19.4 0.1 8.5 5.9 0.0 3.8 2 2 0 2 2 2 2 Dienelactone hydrolase family Palm_thioest PF02089.15 RLN32140.1 - 0.0011 18.8 0.0 0.33 10.7 0.0 2.3 2 0 0 2 2 2 2 Palmitoyl protein thioesterase BAAT_C PF08840.11 RLN32140.1 - 0.0035 17.3 0.0 3.2 7.6 0.0 2.8 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 RLN32140.1 - 0.0052 16.5 0.2 7.1 6.2 0.0 3.5 4 1 0 4 4 4 2 alpha/beta hydrolase fold Esterase_phd PF10503.9 RLN32140.1 - 0.015 14.8 0.1 0.96 8.9 0.0 2.4 2 1 0 2 2 2 0 Esterase PHB depolymerase DUF3089 PF11288.8 RLN32140.1 - 0.044 13.3 0.0 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) Thioesterase PF00975.20 RLN32140.1 - 0.15 12.2 0.0 8.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Thioesterase domain WSD PF15613.6 RLN32142.1 - 3.6e-15 56.2 0.0 3.6e-15 56.2 0.0 4.0 4 2 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD PF00628.29 RLN32142.1 - 1.3e-11 44.1 40.1 5.3e-08 32.6 9.4 4.4 4 0 0 4 4 4 2 PHD-finger DDT PF02791.17 RLN32142.1 - 2.1e-11 43.9 2.8 2.1e-11 43.9 2.8 2.3 3 0 0 3 3 3 1 DDT domain PHD_2 PF13831.6 RLN32142.1 - 0.00012 21.6 2.9 0.00012 21.6 2.9 4.0 4 0 0 4 4 4 2 PHD-finger WHIM1 PF15612.6 RLN32142.1 - 0.001 18.6 0.0 0.003 17.1 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 AhpC-TSA PF00578.21 RLN32143.1 - 4.4e-35 120.3 0.0 6.1e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RLN32143.1 - 2.7e-13 49.9 0.0 3.6e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 RLN32143.1 - 4.8e-08 32.7 0.1 1e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 RLN32143.1 - 0.068 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 SCO1/SenC LHC PF00556.20 RLN32144.1 - 0.012 15.8 0.2 0.018 15.2 0.2 1.2 1 0 0 1 1 1 0 Antenna complex alpha/beta subunit COX7C PF02935.16 RLN32144.1 - 0.23 11.7 2.3 1.5 9.1 2.3 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIIc Kinetochor_Ybp2 PF08568.10 RLN32145.1 - 0.062 11.8 0.2 9.7 4.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family, YAP/Alf4/glomulin MFS_1 PF07690.16 RLN32160.1 - 1.2e-09 37.6 9.5 1.5e-09 37.2 9.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN32160.1 - 0.071 12.0 13.9 0.16 10.8 13.9 1.5 1 1 0 1 1 1 0 Sugar (and other) transporter adh_short PF00106.25 RLN32206.1 - 0.0012 18.4 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase CCDC53 PF10152.9 RLN32207.1 - 2.1e-58 197.1 0.2 2.5e-41 141.7 0.0 2.9 2 1 0 2 2 2 2 Subunit CCDC53 of WASH complex cNMP_binding PF00027.29 RLN32208.1 - 4.9e-19 68.2 0.0 1.2e-18 66.9 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN32208.1 - 1.4e-17 63.7 1.7 1.4e-17 63.7 1.7 2.3 2 1 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 RLN32208.1 - 0.002 18.0 0.5 0.002 18.0 0.5 3.5 3 1 0 3 3 3 1 Ion channel Mannosyl_trans3 PF11051.8 RLN32209.1 - 8.2e-28 97.5 0.0 9.2e-27 94.1 0.0 2.3 2 1 0 2 2 2 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 RLN32209.1 - 0.075 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase EMP24_GP25L PF01105.24 RLN32212.1 - 7.3e-05 22.8 0.1 8.6e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PH PF00169.29 RLN32213.1 - 5.9e-05 23.5 0.0 8.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 PH domain Thymidylat_synt PF00303.19 RLN32214.1 - 1.3e-117 391.7 0.0 1.6e-117 391.4 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 RLN32214.1 - 3.4e-40 137.4 0.0 8e-40 136.2 0.0 1.6 2 0 0 2 2 2 1 Dihydrofolate reductase Myb_DNA-binding PF00249.31 RLN32215.1 - 1.1e-30 105.5 2.8 1.5e-15 57.1 1.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN32215.1 - 2.5e-26 91.7 1.0 2.3e-18 66.2 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN32215.1 - 3.6e-08 33.2 0.5 0.00015 21.6 0.1 2.3 1 1 1 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 RLN32215.1 - 5.9e-06 26.4 0.4 0.023 14.9 0.0 2.4 2 0 0 2 2 2 2 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 RLN32215.1 - 0.014 15.5 0.1 0.72 9.9 0.0 2.5 1 1 1 2 2 2 0 SLIDE adh_short PF00106.25 RLN32216.1 - 1.7e-07 30.9 0.0 3.9e-07 29.7 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN32216.1 - 0.00018 21.1 0.0 0.0011 18.6 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN32216.1 - 0.052 13.5 0.0 0.081 12.8 0.0 1.2 1 0 0 1 1 1 0 KR domain Ldh_1_N PF00056.23 RLN32216.1 - 0.099 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 RLN32217.1 - 2.6e-06 27.1 0.0 1.5e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.8 RLN32217.1 - 0.007 16.1 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase EF-hand_5 PF13202.6 RLN32218.1 - 1e-18 65.9 0.7 1.9e-05 23.9 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 RLN32218.1 - 5.9e-18 63.2 0.9 3.3e-05 23.5 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 RLN32218.1 - 1.2e-17 62.1 0.8 4.8e-05 22.6 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 RLN32218.1 - 6.9e-15 55.3 7.3 6.6e-08 32.9 0.2 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 RLN32218.1 - 3.2e-09 36.5 0.2 0.013 15.3 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain pair ZZ PF00569.17 RLN32218.1 - 0.00012 21.8 18.2 0.008 16.0 5.5 2.7 2 1 0 2 2 2 2 Zinc finger, ZZ type Dockerin_1 PF00404.18 RLN32218.1 - 0.00049 20.2 0.0 0.037 14.2 0.0 2.9 2 1 1 3 3 3 2 Dockerin type I domain SPARC_Ca_bdg PF10591.9 RLN32218.1 - 0.0014 18.9 0.0 0.04 14.2 0.0 2.3 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 RLN32218.1 - 0.073 12.9 0.0 6.7 6.7 0.0 2.6 2 0 0 2 2 2 0 EF hand C1_1 PF00130.22 RLN32218.1 - 0.69 9.8 13.2 1.2 9.1 2.3 2.6 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_4 PF14570.6 RLN32218.1 - 5.6 6.9 17.3 2.5 8.0 4.1 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Sin3_corepress PF08295.12 RLN32219.1 - 1.8e-37 127.3 0.0 1.8e-37 127.3 0.0 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor Sin3a_C PF16879.5 RLN32219.1 - 2.4e-36 125.9 0.0 2.4e-36 125.9 0.0 3.7 3 2 0 3 3 3 1 C-terminal domain of Sin3a protein CDC24_OB1 PF17246.2 RLN32219.1 - 0.021 14.9 2.4 0.061 13.5 0.2 2.7 2 1 0 2 2 2 0 Cell division control protein 24, OB domain 1 cNMP_binding PF00027.29 RLN32220.1 - 1.5e-10 41.0 0.1 0.0014 18.7 0.0 3.1 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain zf-BED PF02892.15 RLN32226.1 - 8.1e-11 41.8 5.3 1.9e-05 24.6 1.8 2.6 2 0 0 2 2 2 2 BED zinc finger zf-C2HE PF16278.5 RLN32226.1 - 0.15 12.5 0.3 0.35 11.4 0.3 1.6 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger RCDG1 PF15725.5 RLN32226.1 - 2.5 8.6 8.2 0.41 11.1 2.6 2.6 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein RNA12 PF10443.9 RLN32228.1 - 0.039 12.7 1.6 0.053 12.3 1.6 1.1 1 0 0 1 1 1 0 RNA12 protein Gal-bind_lectin PF00337.22 RLN32228.1 - 0.093 12.3 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Galactoside-binding lectin Ufd2P_core PF10408.9 RLN32229.1 - 0.009 14.7 0.0 0.01 14.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core PEHE PF15275.6 RLN32229.1 - 0.065 13.9 0.2 0.084 13.5 0.2 1.2 1 0 0 1 1 1 0 PEHE domain TT_ORF1 PF02956.14 RLN32231.1 - 1.4 7.5 5.5 1.8 7.2 5.5 1.1 1 0 0 1 1 1 0 TT viral orf 1 DUF4188 PF13826.6 RLN32233.1 - 0.052 13.9 0.2 0.092 13.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4188) PDZ_6 PF17820.1 RLN32266.1 - 5.8e-09 35.7 0.1 2.4e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 RLN32266.1 - 4.3e-05 23.8 0.0 0.046 14.1 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 RLN32266.1 - 0.13 12.6 0.0 19 5.7 0.0 2.6 2 0 0 2 2 2 0 PDZ domain DUF4129 PF13559.6 RLN32266.1 - 7.3 6.9 6.8 25 5.2 0.6 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4129) SPX PF03105.19 RLN32266.1 - 8.1 6.3 11.2 28 4.5 8.7 2.1 2 0 0 2 2 2 0 SPX domain RPN6_N PF18055.1 RLN32269.1 - 2.1e-24 86.1 0.4 2.1e-24 86.1 0.4 3.4 3 1 1 4 4 4 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 RLN32269.1 - 3.3e-16 59.7 1.4 4.1e-15 56.2 0.7 2.7 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 RLN32269.1 - 2.2e-08 33.7 0.7 4.4e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 RLN32269.1 - 0.0014 18.0 4.6 0.0014 18.0 4.6 2.4 2 1 0 3 3 3 1 MalT-like TPR region Rx_N PF18052.1 RLN32269.1 - 0.016 15.4 1.4 0.035 14.4 0.1 2.2 2 0 0 2 2 2 0 Rx N-terminal domain DUF410 PF04190.13 RLN32269.1 - 0.035 13.9 5.0 1.7 8.4 0.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF410) PSD2 PF07624.11 RLN32269.1 - 0.064 13.0 0.2 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) DUF5397 PF17375.2 RLN32269.1 - 0.21 11.3 0.5 1.5 8.6 0.0 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5397) TPR_14 PF13428.6 RLN32269.1 - 0.5 11.3 8.8 39 5.4 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN32269.1 - 1.1 9.2 7.6 1.7 8.6 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat GST_C_3 PF14497.6 RLN32270.1 - 3.6e-06 27.1 0.0 5.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RLN32270.1 - 0.0021 18.1 0.0 0.0049 16.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RLN32270.1 - 0.031 14.5 0.0 0.048 13.9 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MRP-S34 PF16053.5 RLN32271.1 - 8.3e-13 48.1 0.0 8.9e-13 48.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 Thioredoxin_6 PF13848.6 RLN32272.1 - 9.7e-08 32.1 0.0 0.0056 16.6 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.20 RLN32272.1 - 9e-06 25.6 0.0 0.4 10.7 0.0 4.5 5 1 0 5 5 5 2 Thioredoxin FliT PF05400.13 RLN32272.1 - 0.012 16.4 0.6 0.031 15.1 0.6 1.7 1 0 0 1 1 1 0 Flagellar protein FliT RhlB PF12300.8 RLN32272.1 - 0.071 13.2 2.3 0.18 12.0 2.3 1.6 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB GST_N_3 PF13417.6 RLN32273.1 - 1.4e-10 41.5 0.0 1.4e-10 41.4 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RLN32273.1 - 1.1e-09 38.5 0.0 1.2e-09 38.4 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN32273.1 - 8e-07 29.3 0.0 8.5e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NUC153 PF08159.12 RLN32273.1 - 0.024 14.4 0.1 6.9 6.6 0.0 2.6 3 0 0 3 3 3 0 NUC153 domain GST_N PF02798.20 RLN32274.1 - 7e-09 35.9 0.0 3e-08 33.9 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 RLN32274.1 - 2.8e-08 34.1 0.0 1.8e-05 25.1 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RLN32274.1 - 3.8e-06 27.0 0.0 8.6e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RLN32274.1 - 3.3e-05 24.0 0.3 0.00028 21.0 0.2 2.4 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RLN32274.1 - 0.0008 19.7 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN32274.1 - 0.0062 16.5 0.1 0.018 15.1 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain WD40 PF00400.32 RLN32275.1 - 7.3e-22 77.3 20.3 0.0048 17.7 0.1 9.8 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN32275.1 - 6.1e-10 39.3 1.3 0.0077 16.5 0.3 5.4 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RLN32275.1 - 0.017 14.5 0.0 1 8.6 0.0 2.5 2 1 0 2 2 2 0 WD40-like domain Nup160 PF11715.8 RLN32275.1 - 0.13 10.8 3.5 3.7 6.1 0.2 2.9 1 1 1 3 3 3 0 Nucleoporin Nup120/160 GST_C PF00043.25 RLN32277.1 - 5.1e-06 26.6 0.1 7e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RLN32277.1 - 0.0002 21.5 0.1 0.00036 20.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RLN32277.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_3 PF00933.21 RLN32292.1 - 2.1e-50 171.9 0.0 2.8e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN32292.1 - 1.4e-07 31.7 0.0 2.4e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Peptidase_M1 PF01433.20 RLN32300.1 - 9.6e-83 277.0 1.0 1.6e-82 276.3 1.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 RLN32300.1 - 2.3e-76 257.3 6.9 3.8e-76 256.6 5.2 2.2 3 0 0 3 3 3 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 RLN32300.1 - 9.2e-35 120.5 0.0 6.7e-34 117.7 0.0 2.2 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain LSM PF01423.22 RLN32317.1 - 2.9e-12 46.1 0.0 4.5e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RLN32317.1 - 0.00066 19.8 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain RhoGAP PF00620.27 RLN32318.1 - 2e-09 37.4 0.2 0.0016 18.3 0.1 2.4 2 0 0 2 2 2 2 RhoGAP domain DUF2277 PF10041.9 RLN32318.1 - 0.0012 19.2 0.0 0.0061 16.9 0.0 2.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2277) PH_8 PF15409.6 RLN32318.1 - 0.0091 16.3 0.0 0.073 13.4 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain UPF0552 PF10574.9 RLN32318.1 - 0.0096 15.3 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 1 Arp2/3-interacting proteins Arpin PH PF00169.29 RLN32318.1 - 0.02 15.4 0.6 0.069 13.7 0.0 2.2 2 1 0 2 2 2 0 PH domain Ion_trans PF00520.31 RLN32319.1 - 2.9e-11 43.1 5.7 4.7e-10 39.1 5.7 2.2 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RLN32319.1 - 5.4e-11 42.3 4.6 5.4e-11 42.3 4.6 2.1 2 0 0 2 2 2 1 Ion channel DUF3228 PF11539.8 RLN32320.1 - 1.3e-81 272.8 0.0 1.6e-81 272.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) TCTP PF00838.17 RLN32320.1 - 0.035 14.4 0.0 0.055 13.8 0.0 1.2 1 0 0 1 1 1 0 Translationally controlled tumour protein DnaJ PF00226.31 RLN32321.1 - 3.6e-05 23.8 0.0 7.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain GYF_2 PF14237.6 RLN32321.1 - 0.017 14.9 0.0 0.064 13.1 0.0 2.0 2 0 0 2 2 2 0 GYF domain 2 ECSIT_C PF14784.6 RLN32321.1 - 0.18 12.1 0.0 0.28 11.5 0.0 1.2 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein VIR_N PF15912.5 RLN32321.1 - 0.9 9.1 6.1 1.3 8.5 6.1 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Pkinase_Tyr PF07714.17 RLN32322.1 - 5.2e-52 176.7 0.0 6.2e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN32322.1 - 1e-50 172.6 0.0 1.3e-50 172.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 RLN32322.1 - 0.0029 16.6 0.0 0.14 11.1 0.0 2.0 2 0 0 2 2 2 2 Haspin like kinase domain Pkinase_fungal PF17667.1 RLN32322.1 - 0.003 16.4 0.0 0.0044 15.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN32322.1 - 0.045 13.7 0.1 0.27 11.1 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cu-binding_MopE PF11617.8 RLN32322.1 - 0.045 13.9 0.1 0.085 13.0 0.1 1.4 1 0 0 1 1 1 0 Putative metal-binding motif Kdo PF06293.14 RLN32322.1 - 0.049 13.0 0.1 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RWP-RK PF02042.15 RLN32323.1 - 7.2e-17 61.1 0.2 1.5e-16 60.1 0.2 1.6 1 0 0 1 1 1 1 RWP-RK domain GP67 PF17634.2 RLN32323.1 - 9 6.8 11.4 0.6 10.6 5.2 2.0 2 0 0 2 2 2 0 Gene product 67 Med13_C PF06333.12 RLN32324.1 - 1.3e-13 51.0 9.5 1.5e-07 31.0 0.2 3.3 2 2 1 3 3 3 2 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 RLN32324.1 - 7.8e-07 29.1 4.4 2.7e-05 24.1 0.0 3.4 3 1 1 4 4 4 2 MID domain of medPIWI Med13_N PF11597.8 RLN32324.1 - 5e-06 26.1 0.0 1.3e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal GAS PF13851.6 RLN32325.1 - 0.00034 20.0 7.7 0.00034 20.0 7.7 3.2 3 0 0 3 3 3 1 Growth-arrest specific micro-tubule binding HALZ PF02183.18 RLN32325.1 - 0.017 15.3 8.4 2.4 8.4 1.2 3.9 2 1 0 2 2 2 0 Homeobox associated leucine zipper RuBisCO_large_N PF02788.16 RLN32325.1 - 0.08 13.1 0.0 0.39 10.9 0.0 2.0 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain Unstab_antitox PF09720.10 RLN32325.1 - 0.25 11.4 5.0 6.2 7.0 0.4 3.1 2 0 0 2 2 2 0 Putative addiction module component TPR_MLP1_2 PF07926.12 RLN32325.1 - 0.3 11.2 23.5 1.7 8.7 7.4 3.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 RLN32325.1 - 3.5 8.3 17.9 0.13 12.9 4.7 3.5 2 1 1 3 3 3 0 Initiation control protein YabA SOGA PF11365.8 RLN32325.1 - 8.7 7.6 15.1 1.1 10.4 5.8 3.1 1 1 2 3 3 3 0 Protein SOGA KNOX2 PF03791.13 RLN32326.1 - 0.0071 15.8 0.8 0.41 10.2 0.3 3.0 2 0 0 2 2 2 1 KNOX2 domain DUF4135 PF13575.6 RLN32326.1 - 0.098 12.0 9.7 0.076 12.3 6.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4135) Pkinase_Tyr PF07714.17 RLN32327.1 - 2.5e-51 174.4 0.0 3.2e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN32327.1 - 4.3e-50 170.5 0.0 5.8e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 RLN32327.1 - 0.0099 14.7 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 RLN32327.1 - 0.025 13.5 0.0 0.37 9.7 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 RLN32327.1 - 0.061 12.7 0.1 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN32327.1 - 0.088 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cu-binding_MopE PF11617.8 RLN32327.1 - 0.16 12.1 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative metal-binding motif AA_permease_2 PF13520.6 RLN32339.1 - 3.4e-13 49.2 23.9 3.9e-13 49.0 23.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN32339.1 - 1.2e-09 37.3 18.0 1.6e-09 36.9 18.0 1.1 1 0 0 1 1 1 1 Amino acid permease TRAM1 PF08390.11 RLN32339.1 - 0.071 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 TRAM1-like protein PIP5K PF01504.18 RLN32340.1 - 5.7e-88 294.7 0.0 8.4e-88 294.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Mito_carr PF00153.27 RLN32341.1 - 8.5e-64 211.5 3.3 6.2e-23 80.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein YgbA_NO PF11756.8 RLN32341.1 - 0.0044 17.3 0.0 0.9 9.9 0.0 2.3 2 0 0 2 2 2 2 Nitrous oxide-stimulated promoter Serine_protease PF18405.1 RLN32341.1 - 0.79 8.8 3.8 2 7.5 1.6 2.5 1 1 1 2 2 2 0 Gammaproteobacterial serine protease Pyrophosphatase PF00719.19 RLN32342.1 - 0.0026 17.6 0.0 0.0028 17.5 0.0 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase Aldo_ket_red PF00248.21 RLN32348.1 - 1.4e-69 234.6 0.0 1.6e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 RLN32349.1 - 7.1e-67 225.7 0.0 8.1e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Transketolase_N PF00456.21 RLN32349.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Abhydrolase_2 PF02230.16 RLN32350.1 - 1.6e-46 158.9 0.0 1.8e-46 158.7 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 RLN32350.1 - 1.6e-07 30.9 2.3 0.0024 17.2 0.1 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 RLN32350.1 - 7.9e-07 28.8 0.7 2.7e-06 27.0 0.0 1.9 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 RLN32350.1 - 2.9e-05 24.8 7.7 0.00012 22.8 2.2 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 RLN32350.1 - 0.00067 19.6 0.2 0.034 14.0 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 RLN32350.1 - 0.0043 16.8 0.0 0.049 13.3 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 RLN32350.1 - 0.0088 15.8 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 RLN32350.1 - 0.0097 15.9 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 Cutinase DLH PF01738.18 RLN32350.1 - 0.015 14.9 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family LIP PF03583.14 RLN32350.1 - 0.1 11.9 0.1 2.5 7.4 0.0 2.3 1 1 1 2 2 2 0 Secretory lipase Abhydro_lipase PF04083.16 RLN32350.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 RLN32350.1 - 0.28 10.8 1.3 16 5.0 0.1 2.6 2 1 1 3 3 3 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 RLN32351.1 - 2.1e-37 129.1 0.0 4.7e-24 85.4 0.0 2.0 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 RLN32351.1 - 1.8e-08 34.0 0.0 2.1e-06 27.2 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 RLN32351.1 - 1.6e-05 24.5 0.0 2.9e-05 23.7 0.0 1.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 RLN32351.1 - 0.0021 17.6 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 RLN32351.1 - 0.025 15.2 0.3 2.6 8.6 0.5 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family FSH1 PF03959.13 RLN32351.1 - 0.043 13.5 0.0 5.6 6.6 0.0 2.2 1 1 0 2 2 2 0 Serine hydrolase (FSH1) Aldo_ket_red PF00248.21 RLN32352.1 - 2.2e-135 450.5 0.0 1.7e-67 227.7 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Pro_sub2 PF18513.1 RLN32352.1 - 0.053 13.7 0.0 3 8.1 0.0 2.3 2 0 0 2 2 2 0 Prodomain subtilisin 2 Rtt106_N PF18215.1 RLN32352.1 - 0.25 11.1 0.5 6.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Histone chaperone Rtt106 N-terminal domain PLDc_2 PF13091.6 RLN32355.1 - 5.5e-14 52.2 0.0 1.8e-10 40.8 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 RLN32355.1 - 0.00044 20.3 4.9 0.12 12.7 0.1 3.4 2 1 0 2 2 2 2 Phospholipase D Active site motif Dynactin_p22 PF07426.11 RLN32356.1 - 2e-17 63.6 3.8 3.4e-16 59.5 3.8 2.0 1 1 0 1 1 1 1 Dynactin subunit p22 ZapB PF06005.12 RLN32356.1 - 0.037 14.5 6.8 3.4 8.2 0.0 2.6 2 0 0 2 2 2 0 Cell division protein ZapB GAS PF13851.6 RLN32356.1 - 0.19 11.0 8.9 0.17 11.2 6.2 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Cep57_MT_bd PF06657.13 RLN32356.1 - 0.41 11.1 5.5 1.4 9.5 0.0 2.7 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF3138 PF11336.8 RLN32356.1 - 0.65 8.5 5.5 0.74 8.4 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) ABC_tran_CTD PF16326.5 RLN32356.1 - 4.8 7.5 8.5 1.1 9.5 0.4 2.8 2 1 1 3 3 3 0 ABC transporter C-terminal domain Arrestin_N PF00339.29 RLN32357.1 - 5.4e-07 29.8 0.0 1.4e-06 28.4 0.0 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 RLN32357.1 - 0.00013 22.4 0.0 0.092 13.2 0.0 2.7 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Aminotran_1_2 PF00155.21 RLN32359.1 - 2.3e-53 181.7 0.0 3.1e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 RLN32359.1 - 0.032 13.2 0.0 0.62 9.0 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class-V Aminotran_MocR PF12897.7 RLN32359.1 - 0.041 12.7 0.0 0.16 10.7 0.0 1.8 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase Cys_Met_Meta_PP PF01053.20 RLN32359.1 - 0.088 11.3 0.0 0.57 8.7 0.0 2.0 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF4407 PF14362.6 RLN32360.1 - 0.12 11.7 2.8 0.17 11.2 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CoA_trans PF01144.23 RLN32361.1 - 2.6e-89 298.3 0.9 1.4e-47 161.9 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 RLN32361.1 - 0.007 16.3 0.1 0.012 15.6 0.1 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain FliG_C PF01706.16 RLN32363.1 - 0.03 14.5 0.3 0.089 13.0 0.1 1.9 2 0 0 2 2 2 0 FliG C-terminal domain Pribosyltran PF00156.27 RLN32364.1 - 3e-08 33.3 0.0 4.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 RLN32364.1 - 0.00033 20.1 0.0 0.00044 19.7 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 RLN32364.1 - 0.056 12.9 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase PLDc_2 PF13091.6 RLN32365.1 - 3.1e-14 53.0 0.0 5e-12 45.9 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 RLN32365.1 - 6.7e-11 41.9 2.5 9.3e-05 22.5 0.3 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 RLN32366.1 - 4.8e-13 49.1 0.0 1.7e-10 40.9 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 RLN32366.1 - 1.2e-07 31.6 3.3 0.014 15.6 0.2 3.3 2 1 0 2 2 2 2 Phospholipase D Active site motif FG-GAP PF01839.23 RLN32367.1 - 0.009 16.1 1.8 0.018 15.2 1.8 1.6 1 0 0 1 1 1 1 FG-GAP repeat F420_oxidored PF03807.17 RLN32368.1 - 8.5e-19 67.9 0.2 1.5e-18 67.2 0.2 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent P5CR_dimer PF14748.6 RLN32368.1 - 2.6e-11 43.7 0.0 6.8e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation PDH PF02153.17 RLN32368.1 - 2.5e-05 23.4 0.4 3.9e-05 22.8 0.4 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_Gly3P_dh_N PF01210.23 RLN32368.1 - 0.0002 21.3 0.2 0.0035 17.3 0.1 2.1 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 RLN32368.1 - 0.0005 19.7 0.0 0.0029 17.2 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 RLN32368.1 - 0.00074 19.7 0.4 0.0013 19.0 0.4 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase OCD_Mu_crystall PF02423.15 RLN32368.1 - 0.011 14.7 0.1 0.019 13.9 0.1 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family UDPG_MGDP_dh_C PF03720.15 RLN32368.1 - 0.048 14.1 0.1 0.083 13.3 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 3HCDH_N PF02737.18 RLN32368.1 - 0.25 11.2 1.5 3.6 7.4 0.0 2.2 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-HC5HC2H_2 PF13832.6 RLN32369.1 - 2e-21 76.2 0.9 2e-21 76.2 0.9 3.0 3 0 0 3 3 3 1 PHD-zinc-finger like domain ResIII PF04851.15 RLN32369.1 - 3.3e-18 66.3 0.0 6.8e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RLN32369.1 - 4.9e-18 65.5 0.1 1e-17 64.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RLN32369.1 - 1.1e-14 54.7 0.0 3e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-HC5HC2H PF13771.6 RLN32369.1 - 1.1e-14 54.4 0.1 1.1e-14 54.4 0.1 3.3 4 0 0 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.29 RLN32369.1 - 3.8e-11 42.7 25.6 7.5e-10 38.6 5.6 4.3 4 0 0 4 4 4 2 PHD-finger PHD_2 PF13831.6 RLN32369.1 - 8e-11 41.3 3.3 8e-11 41.3 3.3 3.4 3 0 0 3 3 3 2 PHD-finger zf-RanBP PF00641.18 RLN32369.1 - 1.3e-06 27.6 2.2 1.3e-06 27.6 2.2 2.4 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-PHD-like PF15446.6 RLN32369.1 - 0.0055 16.3 4.3 0.0055 16.3 4.3 2.1 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 RLN32369.1 - 0.81 9.7 13.5 0.018 14.9 3.6 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 ELMO_CED12 PF04727.13 RLN32370.1 - 3.8e-21 76.0 0.0 5.7e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family DIX PF00778.17 RLN32370.1 - 0.00033 20.4 0.0 0.00077 19.3 0.0 1.6 2 0 0 2 2 2 1 DIX domain Pkinase PF00069.25 RLN32371.1 - 0.026 13.9 0.0 0.027 13.9 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain Podoplanin PF05808.11 RLN32372.1 - 1.2e-05 25.4 0.1 1.7e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Podoplanin Rax2 PF12768.7 RLN32372.1 - 0.0014 18.1 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity FixQ PF05545.11 RLN32372.1 - 0.0047 16.9 0.2 0.0047 16.9 0.2 1.7 2 0 0 2 2 2 1 Cbb3-type cytochrome oxidase component FixQ Amnionless PF14828.6 RLN32372.1 - 0.01 14.7 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 0 Amnionless Man-6-P_recep PF02157.15 RLN32372.1 - 0.017 14.3 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate receptor Syndecan PF01034.20 RLN32372.1 - 0.019 14.8 0.3 0.041 13.8 0.3 1.5 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 RLN32372.1 - 0.02 15.8 0.1 0.096 13.6 0.1 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PTP_tm PF18861.1 RLN32372.1 - 0.025 14.6 2.8 0.037 14.0 2.5 1.5 1 1 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF5326 PF17260.2 RLN32372.1 - 0.029 14.5 0.3 0.054 13.6 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5326) Protocadherin PF08374.11 RLN32372.1 - 0.032 14.2 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Protocadherin Mid2 PF04478.12 RLN32372.1 - 0.034 14.0 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Phage_HK97_TLTM PF06120.11 RLN32372.1 - 0.067 12.4 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 Tail length tape measure protein PepSY_TM PF03929.16 RLN32372.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM region S1FA PF04689.13 RLN32372.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 DNA binding protein S1FA DUF2207 PF09972.9 RLN32372.1 - 0.17 10.6 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3430 PF11912.8 RLN32372.1 - 0.36 10.9 6.8 0.83 9.7 6.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3430) MtrF PF09472.10 RLN32372.1 - 0.77 9.2 3.3 1.3 8.5 3.3 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF202 PF02656.15 RLN32372.1 - 1.6 9.3 4.2 5.5 7.5 4.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Podoplanin PF05808.11 RLN32373.1 - 4.5e-05 23.6 0.1 9.8e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Podoplanin PTP_tm PF18861.1 RLN32373.1 - 0.00025 21.1 0.2 0.00049 20.2 0.2 1.5 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J PepSY_TM PF03929.16 RLN32373.1 - 0.0087 15.8 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 1 PepSY-associated TM region Phage_Coat_B PF05356.11 RLN32373.1 - 0.033 14.1 0.2 0.12 12.2 0.2 2.0 1 0 0 1 1 1 0 Phage Coat protein B EphA2_TM PF14575.6 RLN32373.1 - 0.043 14.7 0.2 0.15 13.0 0.1 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 RLN32373.1 - 0.059 13.1 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF3827 PF12877.7 RLN32373.1 - 0.17 10.3 0.0 0.21 9.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) La PF05383.17 RLN32374.1 - 8.9e-16 57.7 0.4 1.3e-15 57.1 0.4 1.2 1 0 0 1 1 1 1 La domain Polyketide_cyc PF03364.20 RLN32374.1 - 0.0011 19.2 0.2 0.002 18.3 0.1 1.5 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Pkinase_Tyr PF07714.17 RLN32377.1 - 1.5e-42 145.7 0.0 2.5e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN32377.1 - 7.5e-37 127.1 0.0 1.3e-36 126.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ABC1 PF03109.16 RLN32377.1 - 0.0027 17.9 0.0 0.016 15.3 0.0 2.1 2 0 0 2 2 2 1 ABC1 family DUF1272 PF06906.11 RLN32377.1 - 0.078 13.1 1.5 2.4 8.3 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DZR PF12773.7 RLN32377.1 - 0.096 12.7 1.3 0.22 11.6 1.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon APH PF01636.23 RLN32377.1 - 0.11 12.3 0.0 0.11 12.3 0.0 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 RLN32378.1 - 2.1e-26 92.8 0.0 2.5e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN32378.1 - 1.4e-21 77.1 0.0 1.9e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DZR PF12773.7 RLN32378.1 - 0.00032 20.7 0.9 0.00061 19.8 0.9 1.4 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 RLN32378.1 - 0.00096 19.9 1.7 0.0017 19.1 1.7 1.5 1 0 0 1 1 1 1 zinc-ribbon family UPF0547 PF10571.9 RLN32378.1 - 0.0016 18.5 10.1 0.0037 17.3 10.1 1.7 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 zf_UBZ PF18439.1 RLN32378.1 - 0.45 10.2 2.9 4.4 7.0 0.5 2.5 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger A2L_zn_ribbon PF08792.10 RLN32378.1 - 0.54 10.1 0.1 0.54 10.1 0.1 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.10 RLN32378.1 - 0.86 9.8 6.2 0.95 9.6 0.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 RLN32378.1 - 1.1 9.0 10.6 3 7.7 10.6 1.8 1 1 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 RLN32378.1 - 6.2 6.4 8.4 0.89 9.0 0.3 2.1 1 1 1 2 2 2 0 zinc-ribbon domain Dimer_Tnp_hAT PF05699.14 RLN32399.1 - 0.0016 18.2 0.0 0.0042 16.8 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 RLN32399.1 - 0.0035 17.3 1.2 0.0045 17.0 0.2 1.7 2 0 0 2 2 2 1 BED zinc finger Laminin_II PF06009.12 RLN32399.1 - 0.057 13.4 0.2 0.12 12.3 0.2 1.6 1 0 0 1 1 1 0 Laminin Domain II DUF1515 PF07439.11 RLN32399.1 - 0.11 12.6 0.6 0.26 11.3 0.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) TPR_1 PF00515.28 RLN32400.1 - 3.6e-15 55.1 10.6 0.0028 17.4 0.2 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 RLN32400.1 - 1.1e-12 47.0 11.8 0.0019 18.1 0.3 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 RLN32400.1 - 1e-07 32.1 5.7 0.002 18.4 2.8 4.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN32400.1 - 7.2e-06 26.5 12.2 1.2e-05 25.9 3.2 4.0 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN32400.1 - 8e-06 26.3 3.7 1.4e-05 25.5 1.2 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN32400.1 - 9.8e-06 25.2 8.2 0.86 9.8 0.2 5.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN32400.1 - 1.1e-05 25.3 5.9 0.13 12.5 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN32400.1 - 4.3e-05 23.7 1.1 4.3e-05 23.7 1.1 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 RLN32400.1 - 4.5e-05 23.8 8.5 0.034 14.8 0.2 4.9 4 1 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.17 RLN32400.1 - 0.00031 21.2 4.6 0.0012 19.3 4.6 2.0 1 0 0 1 1 1 1 Bacterial transcriptional activator domain TPR_17 PF13431.6 RLN32400.1 - 0.00046 20.4 0.6 2.1 8.9 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN32400.1 - 0.0021 18.7 13.4 0.054 14.3 0.7 4.8 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN32400.1 - 0.0099 15.5 7.4 0.029 14.1 0.1 3.6 3 1 1 4 4 4 1 TPR repeat TPR_9 PF13371.6 RLN32400.1 - 0.031 14.4 2.2 0.59 10.3 0.9 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.7 RLN32401.1 - 8.4e-10 39.1 0.2 0.0091 16.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN32401.1 - 5.6e-09 36.1 0.5 0.3 11.5 0.0 5.6 5 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN32401.1 - 1.9e-06 28.3 0.8 6.6 7.4 0.0 5.4 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN32401.1 - 7.4e-05 22.9 0.1 14 6.7 0.0 5.6 7 0 0 7 7 7 2 Ankyrin repeat DUF4287 PF14117.6 RLN32401.1 - 1.5 9.0 4.1 26 5.1 0.1 4.1 3 2 1 4 4 4 0 Domain of unknown function (DUF4287) Ank_4 PF13637.6 RLN32402.1 - 8.2e-17 61.4 0.5 3.6e-12 46.5 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN32402.1 - 5.9e-16 58.8 0.6 5.1e-09 36.6 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RLN32402.1 - 1.1e-12 47.8 6.9 3.1e-05 24.2 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 RLN32402.1 - 2.4e-10 39.7 0.5 0.00022 21.4 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 RLN32402.1 - 1.5e-07 31.5 3.9 7.4e-05 23.0 0.1 3.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) LptF_LptG PF03739.14 RLN32402.1 - 0.12 11.2 0.1 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG ATG101 PF07855.12 RLN32403.1 - 1.2e-32 113.0 0.0 1.6e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 Myosin_head PF00063.21 RLN32406.1 - 2.3e-104 350.0 0.1 4.4e-104 349.1 0.1 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 RLN32406.1 - 5.3e-31 107.7 0.4 5.3e-31 107.7 0.4 1.8 2 0 0 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding YjeJ PF15922.5 RLN32406.1 - 0.0017 17.7 0.5 0.063 12.5 0.1 2.3 2 0 0 2 2 2 2 YjeJ-like PYC_OADA PF02436.18 RLN32407.1 - 1.8e-17 63.8 0.0 2.6e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_lipoyl PF00364.22 RLN32407.1 - 2.1e-16 59.5 2.6 4e-16 58.6 2.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 RLN32407.1 - 2.1e-10 40.3 1.0 0.00033 20.4 0.2 2.7 2 1 1 3 3 3 2 Biotin-lipoyl like HlyD_3 PF13437.6 RLN32407.1 - 6.2e-06 26.9 0.6 0.04 14.6 0.0 2.6 3 0 0 3 3 3 2 HlyD family secretion protein NQRA PF05896.11 RLN32407.1 - 4e-05 23.2 0.4 5.5e-05 22.7 0.4 1.2 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_D23 PF16576.5 RLN32407.1 - 0.00012 21.4 0.3 0.011 14.9 0.1 2.1 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 RLN32407.1 - 0.0059 16.5 0.9 0.012 15.6 0.9 1.6 1 1 0 1 1 1 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 RLN32407.1 - 0.024 14.5 0.5 0.071 13.0 0.3 1.9 1 1 1 2 2 2 0 Glycine cleavage H-protein IncD PF17628.2 RLN32407.1 - 0.092 12.5 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Inclusion membrane protein D PYNP_C PF07831.13 RLN32407.1 - 0.11 12.1 0.7 2.9 7.6 0.0 3.0 3 0 0 3 3 3 0 Pyrimidine nucleoside phosphorylase C-terminal domain DUF2118 PF09891.9 RLN32407.1 - 0.25 11.3 2.6 0.94 9.4 0.2 2.6 2 2 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) Kazal_2 PF07648.15 RLN32411.1 - 1.3e-37 127.6 35.8 3.5e-10 39.8 0.5 4.8 4 0 0 4 4 4 4 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 RLN32411.1 - 1.2e-34 118.0 33.1 1.9e-10 40.6 3.8 4.6 4 0 0 4 4 4 4 Kazal-type serine protease inhibitor domain Nas2_N PF18265.1 RLN32412.1 - 2.8e-22 78.4 0.0 5e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 RLN32412.1 - 8.9e-09 35.1 0.2 1.8e-08 34.1 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RLN32412.1 - 5.7e-06 26.6 0.0 1.1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RLN32412.1 - 3.4e-05 24.1 0.0 7.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 RLN32412.1 - 0.014 15.7 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain ZapB PF06005.12 RLN32412.1 - 3.4 8.2 5.0 31 5.1 0.1 2.6 3 0 0 3 3 3 0 Cell division protein ZapB FANCL_C PF11793.8 RLN32413.1 - 0.00011 22.3 5.6 0.00027 21.1 5.6 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain GIY-YIG PF01541.24 RLN32413.1 - 0.00013 22.1 0.1 0.00067 19.9 0.0 2.0 2 0 0 2 2 2 1 GIY-YIG catalytic domain zf-HC5HC2H PF13771.6 RLN32413.1 - 0.28 11.5 6.7 0.54 10.5 6.7 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain SDF PF00375.18 RLN32414.1 - 6.3e-16 58.4 15.7 3.5e-08 32.9 6.6 2.7 2 1 0 2 2 2 2 Sodium:dicarboxylate symporter family YfhO PF09586.10 RLN32414.1 - 0.062 11.5 1.0 0.1 10.9 1.0 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Ribosomal_S11 PF00411.19 RLN32415.1 - 1.3e-46 157.5 1.8 2.2e-46 156.8 1.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 Pilus_CpaD PF09476.10 RLN32415.1 - 0.0096 15.7 0.6 0.027 14.2 0.6 1.7 1 1 0 1 1 1 1 Pilus biogenesis CpaD protein (pilus_cpaD) DUF2252 PF10009.9 RLN32415.1 - 0.031 13.4 0.0 0.038 13.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) PH PF00169.29 RLN32417.1 - 4.3e-14 52.9 0.0 7.9e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN32417.1 - 0.0042 17.5 0.0 0.0099 16.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Spore_SspJ PF09575.10 RLN32420.1 - 2.1 8.8 4.3 2.6 8.5 0.3 3.1 2 0 0 2 2 2 0 Small spore protein J (Spore_SspJ) Noelin-1 PF12308.8 RLN32420.1 - 2.8 8.0 12.8 8.3 6.5 2.1 3.5 3 0 0 3 3 3 0 Neurogenesis glycoprotein DUF4201 PF13870.6 RLN32420.1 - 7.9 6.2 37.0 0.088 12.5 1.7 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) LMBR1 PF04791.16 RLN32420.1 - 8.5 5.2 6.5 15 4.3 6.5 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein KH_1 PF00013.29 RLN32421.1 - 5.4e-39 131.9 0.0 1.8e-11 43.7 0.0 4.4 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 RLN32421.1 - 0.00074 19.4 0.0 0.068 13.1 0.0 2.7 2 0 0 2 2 2 1 KH domain FAM176 PF14851.6 RLN32421.1 - 0.54 9.9 7.7 0.43 10.2 0.9 3.3 3 0 0 3 3 3 0 FAM176 family NUDIX PF00293.28 RLN32422.1 - 2e-14 53.8 0.0 5.4e-14 52.4 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain Asp PF00026.23 RLN32423.1 - 7.9e-28 97.8 15.1 4.3e-27 95.4 15.1 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RLN32423.1 - 0.00013 22.3 8.9 0.0099 16.1 0.5 3.0 2 2 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 RLN32423.1 - 0.011 16.4 1.2 0.24 12.1 0.1 3.1 3 0 0 3 3 3 0 Aspartyl protease CD34_antigen PF06365.12 RLN32423.1 - 0.03 13.9 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family TAXi_C PF14541.6 RLN32423.1 - 0.042 13.6 0.0 0.17 11.7 0.0 2.0 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 RLN32423.1 - 0.077 13.6 0.3 0.54 10.8 0.0 2.5 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Cadherin_C_2 PF16492.5 RLN32423.1 - 0.094 13.5 0.2 0.31 11.8 0.0 2.0 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Ost4 PF10215.9 RLN32423.1 - 5.6 6.9 8.6 29 4.6 0.0 2.4 2 0 0 2 2 2 0 Oligosaccaryltransferase RRM_5 PF13893.6 RLN32424.1 - 2.5e-17 62.6 0.2 2.7e-09 36.7 0.0 4.3 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 RLN32424.1 - 2.3e-08 33.7 0.2 0.084 12.7 0.0 4.5 3 2 2 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 RLN32424.1 - 0.0003 21.0 0.0 0.0023 18.1 0.0 2.2 2 0 0 2 2 2 1 RRM-like domain SelB-wing_1 PF09105.10 RLN32424.1 - 0.013 15.5 0.1 0.074 13.0 0.0 2.1 2 0 0 2 2 2 0 Elongation factor SelB, winged helix PK_C PF02887.16 RLN32424.1 - 0.11 12.7 0.0 4.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain DUF4833 PF16117.5 RLN32425.1 - 3.3e-41 140.5 0.0 5.9e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4833) Angiomotin_C PF12240.8 RLN32425.1 - 0.018 14.6 10.0 0.6 9.6 0.5 2.2 1 1 1 2 2 2 0 Angiomotin C terminal P_C PF06640.11 RLN32425.1 - 0.022 14.9 1.8 0.032 14.4 1.8 1.3 1 0 0 1 1 1 0 P protein C-terminus HAUS2 PF15003.6 RLN32425.1 - 0.075 12.8 3.1 0.14 11.9 3.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 CCDC53 PF10152.9 RLN32425.1 - 0.1 13.0 6.4 0.19 12.2 6.4 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4525 PF15027.6 RLN32425.1 - 0.11 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) Baculo_PEP_C PF04513.12 RLN32425.1 - 0.17 12.0 1.8 0.29 11.2 1.8 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lectin_N PF03954.14 RLN32425.1 - 0.36 10.6 2.9 1.8 8.3 0.2 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF572 PF04502.13 RLN32425.1 - 0.46 10.1 9.3 0.6 9.7 9.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Nas2_N PF18265.1 RLN32425.1 - 0.49 10.3 4.2 4.5 7.3 0.4 3.0 3 0 0 3 3 3 0 Nas2 N_terminal domain HrpB7 PF09486.10 RLN32425.1 - 0.74 10.2 14.0 10 6.5 14.0 2.2 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) ABC_tran_CTD PF16326.5 RLN32425.1 - 0.92 9.8 9.6 1.5 9.1 7.6 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain Spc7 PF08317.11 RLN32425.1 - 0.96 8.3 8.6 1.3 7.8 8.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HAUS6_N PF14661.6 RLN32425.1 - 0.99 8.9 5.7 1.7 8.2 5.7 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus LCD1 PF09798.9 RLN32425.1 - 1.1 7.7 7.0 1.3 7.4 7.0 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein AAA_13 PF13166.6 RLN32425.1 - 1.2 7.7 8.4 1.5 7.4 8.4 1.1 1 0 0 1 1 1 0 AAA domain UPF0242 PF06785.11 RLN32425.1 - 1.3 9.1 11.2 2.7 8.1 11.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Hep_59 PF07052.11 RLN32426.1 - 7.4e-16 58.8 0.3 7.4e-16 58.8 0.3 2.2 2 1 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 AKAP7_RIRII_bdg PF10470.9 RLN32426.1 - 1.8 8.7 5.7 4.7 7.3 0.4 2.8 3 0 0 3 3 3 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein CAF1A PF12253.8 RLN32427.1 - 9.5e-23 80.2 3.1 9.5e-23 80.2 3.1 3.4 4 0 0 4 4 4 1 Chromatin assembly factor 1 subunit A DUF3537 PF12056.8 RLN32427.1 - 0.95 8.2 2.7 1.9 7.2 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Rep_fac-A_3 PF08661.11 RLN32428.1 - 1.3e-16 60.8 0.0 2.1e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Replication factor A protein 3 Amidohydro_3 PF07969.11 RLN32429.1 - 1.5e-77 262.1 1.7 1.3e-50 173.2 0.0 2.2 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 RLN32429.1 - 9e-14 51.5 0.0 7.5e-11 41.9 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase family PB1 PF00564.24 RLN32429.1 - 0.098 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 PB1 domain Sec66 PF09802.9 RLN32431.1 - 2.9e-08 33.5 4.1 5.8e-08 32.5 2.9 2.0 1 1 0 1 1 1 1 Preprotein translocase subunit Sec66 ApoO PF09769.9 RLN32431.1 - 0.69 9.9 4.4 18 5.3 1.6 2.5 3 0 0 3 3 3 0 Apolipoprotein O Spidroin_N PF16763.5 RLN32431.1 - 0.85 9.6 10.8 0.69 9.9 8.9 1.8 2 0 0 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term DUF4524 PF15025.6 RLN32432.1 - 8.3e-13 48.3 0.0 8.8e-11 41.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4524) DUF4520 PF15016.6 RLN32432.1 - 3.2e-08 33.5 0.2 1.3e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4520) TauE PF01925.19 RLN32433.1 - 5.5e-26 91.7 14.0 2.7e-16 59.9 8.5 2.0 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE SBF PF01758.16 RLN32433.1 - 2.8 7.6 5.9 2.3 7.8 0.2 2.4 2 1 0 2 2 2 0 Sodium Bile acid symporter family MCM PF00493.23 RLN32434.1 - 2.8e-54 183.6 0.0 6.1e-38 130.1 0.0 2.2 1 1 1 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 RLN32434.1 - 1.4e-31 108.9 0.1 2.6e-31 108.1 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RLN32434.1 - 1.5e-22 79.8 0.4 3.4e-22 78.7 0.4 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain LRR_8 PF13855.6 RLN32434.1 - 5.9e-15 54.8 24.3 4.1e-06 26.5 1.2 3.4 1 1 3 4 4 4 4 Leucine rich repeat MCM_N PF14551.6 RLN32434.1 - 3e-13 50.3 0.0 8.9e-13 48.7 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain LRR_4 PF12799.7 RLN32434.1 - 3.7e-13 49.4 7.2 3.8e-05 24.0 0.2 4.2 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) Mg_chelatase PF01078.21 RLN32434.1 - 0.087 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RLN32434.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) LRR_6 PF13516.6 RLN32434.1 - 0.34 11.1 6.1 9.9 6.5 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 RLN32434.1 - 0.34 11.6 11.8 36 5.4 0.1 5.5 5 1 1 6 6 6 0 Leucine Rich Repeat Oxidored_molyb PF00174.19 RLN32435.1 - 5.3e-36 123.8 0.0 7.8e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Cyt-b5 PF00173.28 RLN32435.1 - 4.8e-12 45.9 0.0 7e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Lipoprotein_21 PF14041.6 RLN32435.1 - 0.12 12.5 0.1 0.41 10.8 0.1 1.8 2 0 0 2 2 2 0 LppP/LprE lipoprotein Oxidored_molyb PF00174.19 RLN32436.1 - 4.9e-58 195.6 0.0 7.9e-58 194.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 RLN32436.1 - 2e-43 147.7 1.0 4.5e-43 146.6 1.0 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 RLN32436.1 - 4.1e-14 52.5 0.4 8.3e-14 51.5 0.1 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain BNR PF02012.20 RLN32436.1 - 0.47 10.7 3.2 0.55 10.4 0.8 2.6 2 0 0 2 2 2 0 BNR/Asp-box repeat Nitroreductase PF00881.24 RLN32437.1 - 3.2e-25 89.1 0.0 4.3e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family SfsA PF03749.13 RLN32438.1 - 4e-37 127.2 0.3 2.9e-36 124.4 0.3 2.0 1 1 0 1 1 1 1 Sugar fermentation stimulation protein RE domain SfsA_N PF17746.1 RLN32438.1 - 1.5e-19 69.9 0.5 7.1e-19 67.7 0.5 2.1 1 1 0 1 1 1 1 SfsA N-terminal OB domain AAA PF00004.29 RLN32439.1 - 4.4e-19 69.2 0.1 6.7e-18 65.4 0.1 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Hydin_ADK PF17213.3 RLN32440.1 - 0.0088 16.3 0.2 0.01 16.2 0.2 1.1 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain RFamide_26RFa PF11109.8 RLN32440.1 - 0.03 14.8 1.1 0.035 14.6 1.1 1.2 1 0 0 1 1 1 0 Orexigenic neuropeptide Qrfp/P518 Baculo_PP31 PF05311.11 RLN32440.1 - 0.26 10.7 1.6 0.33 10.4 1.6 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Abhydrolase_1 PF00561.20 RLN32451.1 - 5.2e-16 59.1 0.2 1.1e-14 54.7 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN32451.1 - 2.9e-07 31.3 0.0 4.1e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 RLN32451.1 - 0.022 13.5 0.0 0.033 12.9 0.0 1.2 1 0 0 1 1 1 0 Ndr family Hydrolase_4 PF12146.8 RLN32451.1 - 0.031 13.5 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Myb_DNA-binding PF00249.31 RLN32452.1 - 1.8e-10 40.8 0.0 2.8e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN32452.1 - 0.05 13.8 0.1 0.088 13.1 0.1 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Pap_E4 PF02711.14 RLN32452.1 - 7.4 7.6 8.9 22 6.1 2.8 2.4 2 0 0 2 2 2 0 E4 protein zf-RING_2 PF13639.6 RLN32453.1 - 9.3e-12 45.1 5.8 1.5e-11 44.4 5.8 1.4 1 0 0 1 1 1 1 Ring finger domain PX PF00787.24 RLN32453.1 - 1.2e-10 41.3 1.5 0.00026 21.0 0.1 2.8 2 0 0 2 2 2 2 PX domain zf-rbx1 PF12678.7 RLN32453.1 - 6.2e-08 32.8 3.9 1.3e-07 31.8 3.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 RLN32453.1 - 2.6e-07 30.3 2.1 5e-07 29.4 2.1 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 RLN32453.1 - 8.1e-06 25.6 4.1 1.4e-05 24.9 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN32453.1 - 1.2e-05 25.1 5.1 2.3e-05 24.1 5.1 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN32453.1 - 1.2e-05 25.3 2.8 2.2e-05 24.4 2.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 RLN32453.1 - 0.00012 22.0 1.8 0.00026 21.0 1.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 RLN32453.1 - 0.00058 19.8 5.1 0.00095 19.1 5.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RLN32453.1 - 0.0014 18.4 5.0 0.0024 17.7 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 RLN32453.1 - 0.059 13.0 2.9 0.13 11.9 2.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 RLN32453.1 - 0.078 13.2 4.3 0.18 12.0 4.3 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 RLN32453.1 - 0.87 9.5 8.8 1.5 8.7 8.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.7 RLN32453.1 - 1.1 9.4 8.2 0.15 12.2 3.8 1.9 2 0 0 2 2 1 0 RING-variant domain MtN3_slv PF03083.16 RLN32455.1 - 2.2e-14 53.2 5.9 2.2e-14 53.2 5.9 2.5 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange PsbN PF02468.15 RLN32455.1 - 1.2 9.1 3.2 4.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) peroxidase PF00141.23 RLN32457.1 - 7.9e-39 133.7 0.0 1.4e-38 132.9 0.0 1.4 1 1 0 1 1 1 1 Peroxidase GAF PF01590.26 RLN32458.1 - 2.4e-25 89.7 0.1 7.5e-08 33.1 0.1 3.5 3 0 0 3 3 3 3 GAF domain GAF_2 PF13185.6 RLN32458.1 - 8e-14 52.1 0.1 3.7e-06 27.3 0.1 3.9 3 0 0 3 3 3 3 GAF domain GAF_3 PF13492.6 RLN32458.1 - 6.5e-05 23.3 0.6 0.12 12.7 0.1 4.3 4 1 0 4 4 4 1 GAF domain SOTI PF17079.5 RLN32458.1 - 0.082 13.3 0.0 0.35 11.3 0.0 2.1 1 0 0 1 1 1 0 Male-specific protein scotti CRT-like PF08627.10 RLN32460.1 - 1.8e-52 178.4 2.5 2.3e-52 178.0 2.5 1.1 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 RLN32460.1 - 1.1e-05 25.2 0.2 1.1e-05 25.2 0.2 2.2 2 0 0 2 2 2 1 Solute carrier family 35 Nuc_sug_transp PF04142.15 RLN32460.1 - 0.006 15.8 0.6 0.062 12.5 0.1 2.0 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.20 RLN32460.1 - 0.066 13.4 0.1 0.066 13.4 0.1 2.9 3 1 0 3 3 3 0 EamA-like transporter family Alpha_E1_glycop PF01589.16 RLN32460.1 - 0.15 10.7 0.1 0.23 10.1 0.1 1.1 1 0 0 1 1 1 0 Alphavirus E1 glycoprotein AMP-binding PF00501.28 RLN32463.1 - 2e-97 326.5 0.0 2.6e-97 326.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN32463.1 - 0.0018 19.2 0.0 0.0075 17.2 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Elicitin PF00964.17 RLN32464.1 - 2.5e-19 69.1 2.8 4.1e-19 68.5 2.8 1.3 1 0 0 1 1 1 1 Elicitin AMP-binding PF00501.28 RLN32465.1 - 1e-100 337.3 0.1 1.4e-100 336.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN32465.1 - 0.0034 18.3 0.1 0.0095 16.9 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CDC48_2 PF02933.17 RLN32465.1 - 0.071 12.9 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 Oxidored_FMN PF00724.20 RLN32466.1 - 1.2e-155 518.0 0.0 1.8e-79 267.5 0.0 2.2 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Pam17 PF08566.10 RLN32466.1 - 0.0013 18.6 0.9 0.081 12.8 0.0 3.6 5 1 1 6 6 6 1 Mitochondrial import protein Pam17 AP_endonuc_2 PF01261.24 RLN32466.1 - 0.046 13.1 0.1 12 5.3 0.0 3.3 4 0 0 4 4 4 0 Xylose isomerase-like TIM barrel DUF1885 PF08968.10 RLN32466.1 - 0.064 13.4 0.0 3.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1885) Hydrolase_4 PF12146.8 RLN32467.1 - 1.6e-48 165.1 0.1 6.9e-25 87.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN32467.1 - 1.4e-11 45.5 2.6 1.9e-11 45.0 2.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN32467.1 - 1.8e-08 34.3 0.3 0.00046 19.9 0.1 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 RLN32467.1 - 0.00067 19.3 0.0 0.02 14.5 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 RLN32467.1 - 0.0017 17.9 0.1 2.9 7.3 0.0 3.1 3 0 0 3 3 3 1 Prolyl oligopeptidase family Thioesterase PF00975.20 RLN32467.1 - 0.0045 17.1 0.2 0.03 14.5 0.1 2.0 2 0 0 2 2 2 1 Thioesterase domain PAF-AH_p_II PF03403.13 RLN32467.1 - 0.033 12.7 0.1 0.095 11.2 0.0 1.7 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 RLN32467.1 - 0.039 12.8 0.0 0.11 11.4 0.0 1.7 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 RLN32467.1 - 0.076 12.8 0.2 12 5.6 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase LCAT PF02450.15 RLN32467.1 - 0.12 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase EF-hand_4 PF12763.7 RLN32468.1 - 0.0003 20.7 0.0 0.00058 19.8 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DUF3150 PF11348.8 RLN32468.1 - 0.033 13.4 0.5 0.074 12.3 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3150) DAHP_snth_FXD PF18152.1 RLN32468.1 - 0.11 12.3 0.0 0.37 10.6 0.0 1.9 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain NinB PF05772.12 RLN32468.1 - 0.16 11.8 0.6 1.6 8.6 0.2 2.4 1 1 1 2 2 2 0 NinB protein NYD-SP28 PF14772.6 RLN32468.1 - 0.9 9.6 3.8 0.82 9.8 1.1 2.2 2 1 0 2 2 2 0 Sperm tail Hydrolase_4 PF12146.8 RLN32469.1 - 3.9e-49 167.1 0.5 7.2e-25 87.6 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN32469.1 - 2.6e-10 41.3 0.6 4.4e-10 40.5 0.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN32469.1 - 1.1e-06 28.5 1.6 5.6e-05 22.9 1.8 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN32469.1 - 1.8e-05 24.3 0.6 0.028 13.9 0.0 3.1 3 0 0 3 3 3 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 RLN32469.1 - 0.0059 16.2 0.0 0.25 10.9 0.0 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 RLN32469.1 - 0.0082 16.0 0.2 6.9 6.4 0.0 3.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase PhoPQ_related PF10142.9 RLN32469.1 - 0.013 14.2 0.0 0.017 13.8 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein PAF-AH_p_II PF03403.13 RLN32469.1 - 0.057 11.9 0.1 0.18 10.3 0.1 1.7 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II FSH1 PF03959.13 RLN32469.1 - 0.12 12.1 0.1 0.37 10.4 0.0 2.0 2 1 0 2 2 2 0 Serine hydrolase (FSH1) PGAP1 PF07819.13 RLN32469.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.7 RLN32469.1 - 0.15 10.9 0.1 0.61 8.9 0.1 1.9 1 1 0 1 1 1 0 Chlorophyllase enzyme cNMP_binding PF00027.29 RLN32470.1 - 4.1e-22 78.1 0.0 2.6e-06 27.4 0.0 4.2 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain AMP-binding PF00501.28 RLN32472.1 - 2e-95 319.9 0.0 2.6e-95 319.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN32472.1 - 5.4e-05 24.1 0.2 0.00014 22.8 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain p450 PF00067.22 RLN32475.1 - 2.3e-66 224.5 1.6 3e-66 224.1 1.6 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C48 PF02902.19 RLN32478.1 - 1.1e-10 41.8 0.0 3.3e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SWIM PF04434.17 RLN32478.1 - 0.0098 15.5 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 SWIM zinc finger PAP1 PF08601.10 RLN32483.1 - 0.44 10.2 14.4 0.66 9.6 2.5 2.1 1 1 1 2 2 2 0 Transcription factor PAP1 TEX13 PF15186.6 RLN32483.1 - 6.6 6.4 16.5 1.2 8.9 0.7 2.9 2 1 1 3 3 3 0 Testis-expressed sequence 13 protein family DUF4460 PF14687.6 RLN32488.1 - 0.0015 18.5 0.1 0.0053 16.8 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4460) OrfB_IS605 PF01385.19 RLN32488.1 - 0.44 10.8 3.7 2 8.6 1.4 2.3 2 0 0 2 2 2 0 Probable transposase AATase PF07247.12 RLN32489.1 - 2.5e-05 23.0 0.0 9.4e-05 21.1 0.0 1.7 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 RLN32489.1 - 0.024 13.3 0.0 0.038 12.7 0.0 1.2 1 0 0 1 1 1 0 Condensation domain Catalase PF00199.19 RLN32492.1 - 2e-187 623.0 0.0 2.5e-187 622.7 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 RLN32492.1 - 3.1e-19 68.9 0.3 1.5e-18 66.8 0.1 2.2 2 0 0 2 2 2 1 Catalase-related immune-responsive LRR_4 PF12799.7 RLN32502.1 - 4.5e-14 52.3 9.8 5.2e-07 29.9 0.6 3.5 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN32502.1 - 2.8e-11 43.2 1.5 9e-06 25.3 0.0 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 RLN32502.1 - 4.7e-08 32.7 10.4 0.00056 19.6 0.7 3.0 3 0 0 3 3 3 2 Leucine rich repeat ER PF01133.17 RLN32502.1 - 0.17 11.9 0.0 0.56 10.3 0.0 1.8 1 0 0 1 1 1 0 Enhancer of rudimentary RRN3 PF05327.11 RLN32502.1 - 0.2 10.2 0.3 0.36 9.3 0.3 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Rrn6 PF10214.9 RLN32502.1 - 1.5 7.2 7.3 1.2 7.5 4.9 1.9 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor NAD_binding_11 PF14833.6 RLN32503.1 - 2e-29 102.3 0.0 2.5e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 RLN32503.1 - 3.6e-21 76.0 0.0 6.5e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh PF00984.19 RLN32503.1 - 0.065 13.4 0.1 0.099 12.9 0.1 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain CNH PF00780.22 RLN32508.1 - 4.5e-16 59.3 0.0 6.5e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 CNH domain DHC_N1 PF08385.12 RLN32509.1 - 5.6e-170 566.7 11.5 5.6e-170 566.7 11.5 3.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 RLN32509.1 - 7.1e-149 495.2 0.0 2e-148 493.7 0.0 1.9 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN32509.1 - 1e-124 416.7 14.0 1e-124 416.7 14.0 4.5 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RLN32509.1 - 3.1e-95 318.4 0.0 1e-94 316.7 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RLN32509.1 - 1.1e-85 286.3 2.4 1.1e-85 286.3 2.4 2.6 2 0 0 2 2 2 1 ATP-binding dynein motor region Dynein_C PF18199.1 RLN32509.1 - 1.5e-80 270.7 0.0 5.9e-80 268.8 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 RLN32509.1 - 8.2e-72 240.5 0.0 5.1e-67 224.9 0.0 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region MT PF12777.7 RLN32509.1 - 1.1e-55 189.0 10.3 1.6e-54 185.3 12.1 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 RLN32509.1 - 1.1e-51 175.0 0.0 2.9e-51 173.5 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RLN32509.1 - 5.8e-41 139.3 0.0 4.5e-40 136.5 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain SPA PF08616.10 RLN32509.1 - 5e-29 100.6 0.0 2.5e-28 98.3 0.0 2.4 1 0 0 1 1 1 1 Stabilization of polarity axis Dynein_AAA_lid PF17852.1 RLN32509.1 - 2.1e-27 95.7 0.1 1.7e-26 92.8 0.0 2.8 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RLN32509.1 - 6.3e-23 81.3 0.0 1.7e-07 31.3 0.0 5.2 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 RLN32509.1 - 2.6e-14 53.3 0.1 5.1e-13 49.1 0.0 3.4 5 0 0 5 5 1 1 AAA+ lid domain DUF2347 PF09804.9 RLN32509.1 - 1.5e-11 44.4 0.0 7.9e-11 42.1 0.0 2.3 2 0 0 2 2 1 1 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.12 RLN32509.1 - 4e-10 40.3 0.0 1.2e-09 38.8 0.0 1.8 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking AAA PF00004.29 RLN32509.1 - 3.4e-08 34.0 1.4 0.13 12.7 0.0 5.7 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) Avl9 PF09794.9 RLN32509.1 - 9.5e-08 31.1 0.0 0.0061 15.3 0.0 3.1 1 1 1 2 2 2 2 Transport protein Avl9 AAA_16 PF13191.6 RLN32509.1 - 5.9e-07 30.0 6.4 1.1 9.7 0.0 6.7 6 1 0 6 6 4 2 AAA ATPase domain AAA_22 PF13401.6 RLN32509.1 - 1e-06 29.1 0.1 1.1 9.5 0.0 5.0 4 0 0 4 4 4 2 AAA domain UPF0242 PF06785.11 RLN32509.1 - 0.00026 21.1 3.2 0.00026 21.1 3.2 4.0 4 0 0 4 4 4 1 Uncharacterised protein family (UPF0242) N-terminus FtsK_SpoIIIE PF01580.18 RLN32509.1 - 0.00081 18.8 0.3 0.0048 16.3 0.0 2.5 3 0 0 3 3 3 1 FtsK/SpoIIIE family ADIP PF11559.8 RLN32509.1 - 0.0022 18.1 11.0 0.0022 18.1 11.0 3.2 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 RLN32509.1 - 0.0042 17.6 3.5 0.0042 17.6 3.5 5.7 7 0 0 7 7 2 1 Apg6 coiled-coil region AAA_18 PF13238.6 RLN32509.1 - 0.006 17.1 0.1 0.48 11.0 0.0 4.0 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 RLN32509.1 - 0.018 15.4 0.0 6.1 7.3 0.0 3.4 3 0 0 3 3 3 0 RNA helicase Sigma54_activat PF00158.26 RLN32509.1 - 0.04 13.6 0.0 10 5.8 0.0 3.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.15 RLN32509.1 - 0.049 13.5 0.9 16 5.3 0.0 3.7 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_30 PF13604.6 RLN32509.1 - 0.051 13.3 2.6 3.7 7.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain Yuri_gagarin PF15934.5 RLN32509.1 - 0.095 12.5 4.8 0.12 12.2 1.4 2.8 2 0 0 2 2 2 0 Yuri gagarin PhoH PF02562.16 RLN32509.1 - 0.12 11.8 0.5 0.91 8.9 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 RLN32509.1 - 0.14 12.7 0.8 6.3 7.3 0.0 3.8 3 0 0 3 3 2 0 ABC transporter DUF4201 PF13870.6 RLN32509.1 - 0.62 9.8 14.1 0.59 9.9 6.5 3.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TolA_bind_tri PF16331.5 RLN32509.1 - 1.6 8.9 9.8 2.8 8.1 6.7 3.3 3 0 0 3 3 1 0 TolA binding protein trimerisation FAM76 PF16046.5 RLN32509.1 - 3.2 7.0 5.3 14 4.9 5.3 2.1 1 0 0 1 1 1 0 FAM76 protein EAP30 PF04157.16 RLN32509.1 - 6 6.1 10.4 5.1 6.3 0.1 3.6 3 0 0 3 3 3 0 EAP30/Vps36 family DUF2730 PF10805.8 RLN32509.1 - 8.8 6.5 9.8 0.67 10.1 1.3 3.7 4 0 0 4 4 2 0 Protein of unknown function (DUF2730) PIH1 PF08190.12 RLN32510.1 - 1.7e-22 79.7 0.7 1.2e-21 76.9 0.0 2.6 3 0 0 3 3 3 1 PIH1 N-terminal domain RsgI_N PF12791.7 RLN32510.1 - 0.0034 17.3 0.2 0.007 16.2 0.2 1.4 1 0 0 1 1 1 1 Anti-sigma factor N-terminus Joubert PF15392.6 RLN32510.1 - 0.52 10.0 6.2 0.14 11.9 2.6 1.8 2 0 0 2 2 2 0 Joubert syndrome-associated IQ PF00612.27 RLN32511.1 - 0.0011 18.6 11.1 0.4 10.6 0.1 4.3 3 0 0 3 3 3 3 IQ calmodulin-binding motif CNOT11 PF10155.9 RLN32512.1 - 0.04 14.1 0.2 1.7 8.8 0.0 3.0 3 0 0 3 3 3 0 CCR4-NOT transcription complex subunit 11 RRM_1 PF00076.22 RLN32524.1 - 2.1e-16 59.5 0.0 3e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN32524.1 - 0.01 15.9 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif GRP PF07172.11 RLN32524.1 - 2.6 8.8 19.6 0.94 10.2 16.7 1.7 2 0 0 2 2 2 0 Glycine rich protein family PNISR PF15996.5 RLN32525.1 - 0.2 11.9 12.9 0.34 11.2 12.9 1.4 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR GOLD_2 PF13897.6 RLN32525.1 - 0.31 11.5 1.1 0.59 10.6 1.1 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Thr_dehydrat_C PF00585.18 RLN32526.1 - 7e-26 89.8 0.1 7e-25 86.6 0.0 1.9 2 0 0 2 2 2 1 C-terminal regulatory domain of Threonine dehydratase Arm PF00514.23 RLN32532.1 - 1.5e-34 117.0 20.6 0.00011 22.1 0.1 11.9 11 1 1 12 12 12 9 Armadillo/beta-catenin-like repeat Arylsulfotran_N PF17425.2 RLN32532.1 - 2.4e-08 33.9 0.0 67 3.6 0.0 8.5 9 0 0 9 9 9 0 Arylsulfotransferase Ig-like domain HEAT_EZ PF13513.6 RLN32532.1 - 4.8e-07 30.1 9.0 0.02 15.4 0.0 7.5 1 1 8 10 10 10 7 HEAT-like repeat Arm_2 PF04826.13 RLN32532.1 - 2.1e-05 24.1 0.2 4.3 6.7 0.0 4.7 2 2 4 7 7 7 1 Armadillo-like HEAT PF02985.22 RLN32532.1 - 0.00017 21.5 20.2 40 4.8 0.0 9.9 11 0 0 11 11 11 0 HEAT repeat UNC45-central PF11701.8 RLN32532.1 - 0.004 17.1 0.0 2.2 8.2 0.0 4.0 2 1 2 4 4 4 1 Myosin-binding striated muscle assembly central Atx10homo_assoc PF09759.9 RLN32532.1 - 0.017 15.1 9.8 0.49 10.4 1.0 5.4 4 2 2 7 7 7 0 Spinocerebellar ataxia type 10 protein domain NAD_binding_1 PF00175.21 RLN32532.1 - 0.067 13.8 0.1 1.3e+02 3.2 0.0 5.5 6 1 1 8 8 8 0 Oxidoreductase NAD-binding domain HEAT_PBS PF03130.16 RLN32532.1 - 0.12 13.2 54.4 7.7 7.5 0.1 11.7 12 0 0 12 12 12 0 PBS lyase HEAT-like repeat Nuc_N PF14448.6 RLN32532.1 - 0.19 11.6 7.7 1.3e+02 2.5 0.0 7.3 9 0 0 9 9 9 0 Nuclease N terminal Defensin_big PF14862.6 RLN32532.1 - 4.6 7.6 5.9 3.2e+02 1.7 0.0 5.2 5 0 0 5 5 5 0 Big defensin CBS PF00571.28 RLN32533.1 - 1.3e-08 35.2 0.3 3.8e-08 33.6 0.1 2.0 2 0 0 2 2 2 1 CBS domain I_LWEQ PF01608.17 RLN32533.1 - 0.014 15.7 6.2 0.024 14.9 6.2 1.4 1 0 0 1 1 1 0 I/LWEQ domain GARS_N PF02844.15 RLN32533.1 - 0.14 12.9 1.2 1.3 9.8 0.3 2.2 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain RNA_ligase PF09414.10 RLN32534.1 - 5.3e-27 95.1 0.0 9.1e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 RNA ligase AAA_33 PF13671.6 RLN32534.1 - 1.9e-09 37.8 0.1 4.4e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain PTPlike_phytase PF14566.6 RLN32534.1 - 2.2e-05 24.6 0.0 4.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate AAA_16 PF13191.6 RLN32534.1 - 0.0012 19.3 0.3 0.0042 17.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Y_phosphatase PF00102.27 RLN32534.1 - 0.0014 18.3 0.0 0.0058 16.2 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 RLN32534.1 - 0.0025 17.6 0.0 0.0052 16.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 RLN32534.1 - 0.0031 17.5 0.0 0.0078 16.2 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family AAA_18 PF13238.6 RLN32534.1 - 0.0034 17.9 0.0 0.01 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Y_phosphatase2 PF03162.13 RLN32534.1 - 0.022 14.4 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family LigT_PEase PF02834.16 RLN32534.1 - 0.027 14.6 0.0 0.071 13.3 0.0 1.6 1 0 0 1 1 1 0 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 RLN32534.1 - 0.047 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily AAA_22 PF13401.6 RLN32534.1 - 0.084 13.1 0.0 0.35 11.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain CDKN3 PF05706.12 RLN32534.1 - 0.099 12.3 0.3 0.49 10.0 0.1 2.0 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) KTI12 PF08433.10 RLN32534.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Tmemb_14 PF03647.13 RLN32543.1 - 6.5e-18 65.3 10.5 7.7e-18 65.0 10.5 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C UbiA PF01040.18 RLN32543.1 - 0.031 13.6 4.7 0.035 13.4 4.7 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family Rhomboid PF01694.22 RLN32543.1 - 0.62 10.1 6.6 0.81 9.7 6.6 1.3 1 0 0 1 1 1 0 Rhomboid family PIN_3 PF13470.6 RLN32544.1 - 2.9 8.7 10.4 1.7e+02 3.0 10.4 2.7 1 1 0 1 1 1 0 PIN domain PITH PF06201.13 RLN32545.1 - 7.4e-35 120.4 0.8 6.5e-30 104.3 0.1 2.0 1 1 1 2 2 2 2 PITH domain IMPDH PF00478.25 RLN32546.1 - 1.3e-80 271.0 3.4 3.2e-80 269.7 3.4 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 RLN32546.1 - 3.3e-05 23.1 1.5 5.4e-05 22.4 1.5 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase dCache_3 PF14827.6 RLN32546.1 - 0.035 13.7 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase Aldolase PF01081.19 RLN32546.1 - 0.084 12.3 1.6 0.31 10.4 0.2 2.2 1 1 1 2 2 2 0 KDPG and KHG aldolase Gar1 PF04410.14 RLN32547.1 - 3.3e-31 108.1 0.0 4.5e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region LSM PF01423.22 RLN32548.1 - 2.9e-17 62.1 1.0 1.5e-16 59.8 1.0 1.8 1 1 0 1 1 1 1 LSM domain CIAPIN1 PF05093.13 RLN32548.1 - 0.056 13.9 0.0 0.064 13.8 0.0 1.1 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis ABATE PF07336.11 RLN32549.1 - 0.082 13.6 3.1 0.13 12.9 3.1 1.4 1 0 0 1 1 1 0 Putative stress-induced transcription regulator HTH_3 PF01381.22 RLN32550.1 - 4.4e-13 49.1 0.2 5.8e-13 48.7 0.2 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 RLN32550.1 - 7.3e-05 23.0 0.0 9.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 RLN32550.1 - 0.00021 21.3 0.1 0.00032 20.6 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain TRAP-gamma PF07074.12 RLN32550.1 - 0.0042 16.7 1.0 0.0055 16.3 1.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) XLF PF09302.11 RLN32550.1 - 0.057 13.6 0.1 0.06 13.5 0.1 1.2 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component UQ_con PF00179.26 RLN32561.1 - 3e-14 52.9 0.0 3.4e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TPT PF03151.16 RLN32562.1 - 1.4e-52 178.9 19.6 1.4e-50 172.3 19.6 2.0 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 RLN32562.1 - 4.9e-08 33.2 21.1 6e-06 26.5 9.4 2.9 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 RLN32562.1 - 0.00091 18.5 19.2 0.0036 16.6 14.0 2.6 2 1 0 2 2 2 2 UAA transporter family TMEM234 PF10639.9 RLN32562.1 - 2 8.5 10.0 0.89 9.6 1.7 3.1 2 1 0 3 3 3 0 Putative transmembrane family 234 LZ_Tnp_IS66 PF13007.7 RLN32563.1 - 0.2 12.4 5.5 2.5 8.9 1.3 2.6 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain Ribosomal_L7Ae PF01248.26 RLN32566.1 - 6.1e-25 86.8 0.7 8.6e-25 86.3 0.2 1.4 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family JmjC PF02373.22 RLN32567.1 - 2.4e-14 53.8 0.0 6.2e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 RLN32567.1 - 6.5e-12 45.7 0.0 1.4e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain APH PF01636.23 RLN32567.1 - 5.5e-07 29.8 0.1 0.0026 17.7 0.1 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family SAM_1 PF00536.30 RLN32567.1 - 6.4e-06 26.5 0.0 1.3e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RLN32567.1 - 1.4e-05 25.1 0.0 2.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1679 PF07914.11 RLN32567.1 - 0.039 12.8 0.0 0.47 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Cupin_4 PF08007.12 RLN32567.1 - 0.07 12.6 0.1 0.31 10.4 0.1 2.1 1 1 0 1 1 1 0 Cupin superfamily protein Na_trans_cytopl PF11933.8 RLN32568.1 - 0.0013 18.6 0.1 0.0028 17.5 0.1 1.5 1 0 0 1 1 1 1 Cytoplasmic domain of voltage-gated Na+ ion channel EF-hand_8 PF13833.6 RLN32568.1 - 0.068 13.0 1.5 9.7 6.1 0.2 3.1 3 0 0 3 3 3 0 EF-hand domain pair OmpH PF03938.14 RLN32568.1 - 8.5 6.7 7.5 1 9.7 3.0 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) NDUF_C2 PF06374.11 RLN32569.1 - 0.085 13.0 0.0 0.44 10.7 0.0 2.1 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) TAF1_subA PF14929.6 RLN32570.1 - 2.8e-12 46.8 0.0 5.1e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 TAF RNA Polymerase I subunit A TPR_14 PF13428.6 RLN32570.1 - 0.017 15.9 0.5 20 6.3 0.0 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat STAS_2 PF13466.6 RLN32570.1 - 0.54 10.6 3.6 2.9 8.3 0.1 3.3 3 0 0 3 3 3 0 STAS domain GvpL_GvpF PF06386.11 RLN32571.1 - 3.1 7.7 8.2 11 5.9 8.2 1.8 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF TraH PF06122.11 RLN32573.1 - 0.062 12.6 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein DUF1938 PF09153.10 RLN32573.1 - 0.071 13.2 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) Pkinase_Tyr PF07714.17 RLN32575.1 - 1.5e-59 201.4 0.0 5.2e-44 150.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN32575.1 - 7.3e-52 176.3 0.0 1e-38 133.2 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Arm PF00514.23 RLN32575.1 - 0.0011 18.9 1.6 2.1 8.5 0.0 3.5 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Kinase-like PF14531.6 RLN32575.1 - 0.0026 17.1 0.0 0.6 9.4 0.0 2.6 2 1 0 2 2 2 2 Kinase-like MoaE PF02391.17 RLN32575.1 - 0.016 15.5 0.0 3.5 7.9 0.0 2.8 2 0 0 2 2 2 0 MoaE protein HEAT_2 PF13646.6 RLN32575.1 - 0.18 12.2 2.0 0.64 10.4 0.6 2.3 1 1 1 2 2 2 0 HEAT repeats APH PF01636.23 RLN32575.1 - 1.1 9.1 0.0 1.1 9.1 0.0 3.2 3 0 0 3 3 3 0 Phosphotransferase enzyme family E1-E2_ATPase PF00122.20 RLN32576.1 - 1.6e-53 181.0 3.1 1.4e-52 177.8 1.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 RLN32576.1 - 1.2e-21 78.0 0.1 1.7e-20 74.3 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN32576.1 - 1.1e-18 67.0 0.1 2.3e-18 66.0 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 RLN32576.1 - 1.1e-15 57.0 0.1 5.4e-15 54.8 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RLN32576.1 - 0.0002 21.2 3.0 0.00022 21.0 0.8 2.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 RLN32576.1 - 0.0011 19.4 0.0 0.003 18.0 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Fer4_15 PF13459.6 RLN32578.1 - 0.036 14.8 4.6 0.42 11.4 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain Actin PF00022.19 RLN32580.1 - 1.4e-97 326.9 0.0 1.4e-96 323.6 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 RLN32580.1 - 0.012 14.4 0.0 0.23 10.2 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein FtsA PF14450.6 RLN32580.1 - 0.054 13.9 0.0 0.08 13.4 0.0 1.3 1 0 0 1 1 1 0 Cell division protein FtsA Band_7 PF01145.25 RLN32583.1 - 1.8e-18 67.2 6.1 8.8e-10 38.9 0.0 3.0 3 0 0 3 3 3 2 SPFH domain / Band 7 family RNA_pol_Rpb1_5 PF04998.17 RLN32583.1 - 0.0026 17.3 2.4 0.0041 16.6 2.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Band_7_1 PF13421.6 RLN32583.1 - 0.0042 16.8 1.4 0.011 15.4 0.0 2.1 2 0 0 2 2 2 1 SPFH domain-Band 7 family YlqD PF11068.8 RLN32583.1 - 0.57 10.6 11.9 1.4 9.3 3.3 3.3 1 1 0 2 2 2 0 YlqD protein Mito_carr PF00153.27 RLN32584.1 - 3.1e-55 184.1 1.7 1.2e-17 63.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40_3 PF15911.5 RLN32585.1 - 5.8e-18 64.6 0.0 2e-17 62.9 0.0 2.0 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN32585.1 - 2.1e-10 40.7 0.0 0.0043 17.3 0.0 4.9 3 1 2 5 5 4 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 RLN32585.1 - 7e-06 26.0 0.4 4.2 7.2 0.0 4.9 4 1 1 5 5 5 2 Region in Clathrin and VPS IKI3 PF04762.12 RLN32585.1 - 0.003 15.7 0.0 0.031 12.3 0.0 2.1 2 0 0 2 2 2 1 IKI3 family WD40 PF00400.32 RLN32585.1 - 0.0041 17.9 0.7 2 9.4 0.0 4.8 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 RLN32585.1 - 0.017 14.2 7.1 2.5 7.1 2.6 3.8 4 0 0 4 4 4 0 Coatomer WD associated region Frtz PF11768.8 RLN32585.1 - 0.086 11.1 0.0 6.4 5.0 0.0 3.5 4 1 1 5 5 5 0 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 RLN32585.1 - 0.12 12.2 0.0 0.86 9.4 0.0 2.1 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A DZR PF12773.7 RLN32585.1 - 0.87 9.7 11.4 1.8 8.7 1.1 2.4 1 1 1 2 2 2 0 Double zinc ribbon RIC1 PF07064.13 RLN32585.1 - 0.96 8.8 4.0 9.6 5.5 0.3 2.7 2 0 0 2 2 2 0 RIC1 Rad50_zn_hook PF04423.14 RLN32585.1 - 1.1 9.1 5.7 1.1 9.1 0.0 2.7 2 1 1 3 3 3 0 Rad50 zinc hook motif TPR_7 PF13176.6 RLN32585.1 - 2.2 8.5 18.1 33 4.8 0.3 7.7 7 1 0 7 7 7 0 Tetratricopeptide repeat zf-Di19 PF05605.12 RLN32585.1 - 2.5 8.5 13.8 4.5 7.6 1.5 3.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc-ribbons_6 PF07191.12 RLN32585.1 - 8.5 6.4 10.1 18 5.4 2.6 2.5 1 1 1 2 2 2 0 zinc-ribbons Pkinase PF00069.25 RLN32586.1 - 8.3e-09 35.2 0.1 1.1e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain PH PF00169.29 RLN32586.1 - 1.4e-08 35.2 0.1 3.4e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN32586.1 - 0.021 15.2 0.5 0.068 13.6 0.5 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain Pkinase_Tyr PF07714.17 RLN32586.1 - 0.056 12.7 0.1 0.082 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase EF-hand_1 PF00036.32 RLN32591.1 - 4.1e-20 69.8 7.7 2.2e-08 33.1 0.1 4.0 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 RLN32591.1 - 9.5e-20 68.8 5.2 4.5e-06 26.2 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 RLN32591.1 - 2.2e-12 47.3 10.9 5.3e-08 33.2 4.7 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 RLN32591.1 - 3.7e-12 45.9 2.7 5e-05 23.1 0.2 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 RLN32591.1 - 4.7e-10 38.5 9.8 0.00022 20.6 0.0 4.1 3 1 0 3 3 3 3 EF hand EF-hand_10 PF14788.6 RLN32591.1 - 3.3e-08 33.3 2.3 0.02 14.8 0.0 3.5 3 0 0 3 3 3 2 EF hand DUF2096 PF09869.9 RLN32591.1 - 0.034 14.2 0.4 0.099 12.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) Caleosin PF05042.13 RLN32591.1 - 0.27 11.1 2.3 0.71 9.8 0.1 2.4 2 0 0 2 2 2 0 Caleosin related protein LpxK PF02606.14 RLN32592.1 - 1.4e-51 175.6 0.5 3.3e-51 174.3 0.5 1.5 1 1 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase TIR_3 PF18567.1 RLN32592.1 - 0.14 12.1 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Toll/interleukin-1 receptor domain PAXNEB PF05625.11 RLN32593.1 - 1.1e-71 241.9 0.0 1.3e-71 241.7 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein RF-1 PF00472.20 RLN32594.1 - 1.6e-06 28.0 1.5 2.1e-06 27.6 1.5 1.3 1 0 0 1 1 1 1 RF-1 domain DASH_Spc19 PF08287.11 RLN32594.1 - 0.004 17.1 4.8 0.0052 16.7 4.8 1.2 1 0 0 1 1 1 1 Spc19 BUD22 PF09073.10 RLN32594.1 - 0.0051 16.2 21.0 0.0059 16.0 21.0 1.2 1 0 0 1 1 1 1 BUD22 CNDH2_C PF16858.5 RLN32594.1 - 0.0079 16.1 14.4 0.009 15.9 14.4 1.1 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term Paf1 PF03985.13 RLN32594.1 - 0.036 13.1 13.6 0.039 13.0 13.6 1.0 1 0 0 1 1 1 0 Paf1 SDA1 PF05285.12 RLN32594.1 - 0.34 10.3 26.5 0.41 10.0 26.5 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RLN32594.1 - 0.47 8.6 30.0 0.48 8.6 30.0 1.1 1 0 0 1 1 1 0 Nop14-like family MscS_TM PF12794.7 RLN32594.1 - 0.59 8.9 1.5 0.64 8.8 1.5 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 NPR3 PF03666.13 RLN32594.1 - 0.62 8.8 10.4 0.67 8.7 10.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cnd2 PF05786.14 RLN32594.1 - 0.64 8.6 22.0 0.69 8.5 22.0 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 PPP4R2 PF09184.11 RLN32594.1 - 0.71 9.4 21.8 0.82 9.2 21.8 1.2 1 0 0 1 1 1 0 PPP4R2 DUF4820 PF16091.5 RLN32594.1 - 1.2 8.5 8.6 1.4 8.2 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) IFT57 PF10498.9 RLN32594.1 - 1.6 7.7 12.3 2.1 7.3 12.3 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF913 PF06025.12 RLN32594.1 - 1.8 7.5 4.2 1.9 7.4 4.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RPN2_C PF18004.1 RLN32594.1 - 2.2 8.2 10.4 3.3 7.6 10.4 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CobT PF06213.12 RLN32594.1 - 2.3 7.6 22.5 2.7 7.3 22.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RRN3 PF05327.11 RLN32594.1 - 3.1 6.2 22.1 3.3 6.2 22.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3295 PF11702.8 RLN32594.1 - 4 6.7 20.8 5.7 6.2 20.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) V_ATPase_I PF01496.19 RLN32594.1 - 5.1 4.9 7.9 6.1 4.6 7.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2076 PF09849.9 RLN32594.1 - 5.3 7.0 22.2 7 6.6 22.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TFIIA PF03153.13 RLN32594.1 - 6.2 6.7 31.1 6.9 6.5 31.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 RLN32594.1 - 7.5 4.7 24.2 8 4.6 24.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4748 PF15932.5 RLN32594.1 - 9.9 6.0 8.0 1.7 8.5 4.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4748) HTH_ABP1_N PF18107.1 RLN32597.1 - 0.026 14.3 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain Pcc1 PF09341.10 RLN32597.1 - 0.037 14.2 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 Transcription factor Pcc1 HTH_Tnp_Tc5 PF03221.16 RLN32597.1 - 0.051 13.6 0.4 0.15 12.1 0.2 1.8 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain Baculo_PEP_C PF04513.12 RLN32598.1 - 0.0039 17.2 1.2 0.029 14.4 0.0 2.8 3 1 1 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus SYCE1 PF15233.6 RLN32598.1 - 0.015 15.4 0.8 0.015 15.4 0.8 2.4 3 0 0 3 3 3 0 Synaptonemal complex central element protein 1 FOXP-CC PF16159.5 RLN32598.1 - 0.083 13.5 0.0 0.85 10.3 0.0 2.7 2 0 0 2 2 2 0 FOXP coiled-coil domain PL48 PF15903.5 RLN32598.1 - 0.39 9.7 4.2 2.2 7.2 0.2 2.5 2 0 0 2 2 2 0 Filopodia upregulated, FAM65 AAA_13 PF13166.6 RLN32598.1 - 0.79 8.3 21.1 0.64 8.6 0.2 2.8 2 1 0 2 2 2 0 AAA domain DUF3080 PF11279.8 RLN32598.1 - 1.9 7.6 8.5 0.68 9.1 4.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3080) DUF3037 PF11236.8 RLN32598.1 - 6.8 7.2 6.8 8.2 6.9 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3037) Nab1 PF04902.12 RLN32613.1 - 0.014 15.9 0.3 0.018 15.5 0.3 1.2 1 0 0 1 1 1 0 Conserved region in Nab1 NuA4 PF09340.10 RLN32613.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 DUF4542 PF15075.6 RLN32614.1 - 0.011 16.2 0.3 0.033 14.6 0.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4542) PAC1 PF16094.5 RLN32614.1 - 1.5 7.9 3.2 2 7.5 3.2 1.1 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 BRCA2 PF00634.18 RLN32615.1 - 2.4e-32 110.3 31.6 0.00078 19.1 0.2 10.8 10 0 0 10 10 10 9 BRCA2 repeat BRCA-2_OB1 PF09103.10 RLN32615.1 - 2.4e-27 95.3 0.0 4.8e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 RLN32615.1 - 5.9e-14 52.1 0.0 1.1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 BRCA2, helical Microtub_bd PF16796.5 RLN32615.1 - 0.047 13.6 1.1 6.3 6.7 0.0 4.3 5 0 0 5 5 5 0 Microtubule binding GH97_N PF14508.6 RLN32615.1 - 0.14 11.7 0.0 7.8 5.9 0.0 3.3 3 1 1 4 4 4 0 Glycosyl-hydrolase 97 N-terminal HrpJ PF07201.11 RLN32615.1 - 1.9 8.8 6.5 0.51 10.6 1.9 2.5 2 0 0 2 2 2 0 HrpJ-like domain RRM_1 PF00076.22 RLN32621.1 - 2e-08 33.9 0.0 4.5e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TrmO_C PF18389.1 RLN32621.1 - 0.34 11.1 3.4 1.3 9.2 0.1 3.2 3 0 0 3 3 3 0 TrmO C-terminal domain DUF445 PF04286.12 RLN32621.1 - 4.6 7.0 7.2 2.5 7.8 2.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF445) DSHCT PF08148.12 RLN32622.1 - 3.3e-53 179.7 1.4 1.1e-52 178.1 0.6 2.2 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 RLN32622.1 - 3.5e-26 92.7 0.1 6.9e-26 91.8 0.1 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 RLN32622.1 - 7.4e-16 58.4 0.2 3.7e-15 56.1 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN32622.1 - 5.1e-06 26.8 0.0 1.6e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ski2_N PF17911.1 RLN32622.1 - 0.022 14.6 0.1 0.056 13.3 0.1 1.6 1 0 0 1 1 1 0 Ski2 N-terminal region AAA_22 PF13401.6 RLN32622.1 - 0.073 13.4 0.0 0.31 11.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 RLN32622.1 - 0.099 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein MAT1 PF06391.13 RLN32623.1 - 1.5e-23 83.7 14.1 2.2e-23 83.2 14.1 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_2 PF13639.6 RLN32623.1 - 2.3e-05 24.7 11.2 3.8e-05 23.9 11.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RLN32623.1 - 0.00011 22.0 13.0 0.00018 21.3 13.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 RLN32623.1 - 0.00059 19.7 6.8 0.00059 19.7 6.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN32623.1 - 0.001 19.0 14.2 0.0026 17.7 14.3 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RLN32623.1 - 0.0015 18.3 14.0 0.0035 17.1 14.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RLN32623.1 - 0.0016 18.5 3.1 0.0016 18.5 3.1 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RLN32623.1 - 0.0017 18.2 10.1 0.0031 17.3 10.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 RLN32623.1 - 0.0054 17.0 8.8 0.011 16.1 8.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RLN32623.1 - 0.0073 16.3 7.5 0.014 15.4 7.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger DNA_pol3_chi PF04364.13 RLN32623.1 - 0.021 15.0 1.2 0.069 13.3 0.1 2.1 1 1 1 2 2 2 0 DNA polymerase III chi subunit, HolC zf-ANAPC11 PF12861.7 RLN32623.1 - 0.062 13.4 3.8 0.11 12.6 3.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 RLN32623.1 - 2 8.5 10.1 56 3.9 10.7 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.6 RLN32623.1 - 4.3 7.2 12.6 41 4.1 13.1 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain IBR PF01485.21 RLN32623.1 - 4.4 7.6 10.9 8.2 6.7 8.6 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain LRR_4 PF12799.7 RLN32624.1 - 1.6e-07 31.5 9.0 0.025 15.0 0.2 5.6 6 1 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN32624.1 - 2.4e-05 24.0 13.8 0.065 13.0 0.0 6.2 5 2 1 6 6 6 3 Leucine rich repeat LRR_1 PF00560.33 RLN32624.1 - 0.00048 20.3 11.5 19 6.3 0.0 7.1 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 RLN32624.1 - 0.24 11.5 19.6 3.5 7.9 0.1 6.9 8 0 0 8 8 8 0 Leucine Rich repeat FHA PF00498.26 RLN32625.1 - 5.1e-08 33.1 0.1 1e-07 32.2 0.1 1.6 1 0 0 1 1 1 1 FHA domain CHAT PF12770.7 RLN32625.1 - 5.8e-07 29.2 0.0 1.4e-06 28.0 0.0 1.5 2 0 0 2 2 2 1 CHAT domain NACHT PF05729.12 RLN32625.1 - 1.9e-06 27.9 0.2 9.4e-06 25.6 0.2 2.1 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 RLN32625.1 - 0.0011 19.4 0.1 0.0036 17.7 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RLN32625.1 - 0.0018 18.6 0.8 0.0068 16.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RLN32625.1 - 0.0038 17.7 0.0 0.0076 16.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 RLN32625.1 - 0.0041 17.1 0.0 0.0074 16.2 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain TIP49 PF06068.13 RLN32625.1 - 0.13 11.4 0.1 0.21 10.7 0.1 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Methyltransf_31 PF13847.6 RLN32626.1 - 1.4e-29 102.8 0.0 3.5e-29 101.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN32626.1 - 8.8e-18 64.8 0.0 1.6e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN32626.1 - 4.8e-16 59.2 0.0 8.3e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN32626.1 - 6.1e-11 42.4 0.0 8.8e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN32626.1 - 2.2e-10 41.2 0.0 3.7e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN32626.1 - 6.2e-10 38.8 0.0 1.3e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 RLN32626.1 - 1.7e-05 24.7 0.0 2.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 RLN32626.1 - 0.00034 20.1 0.0 0.00053 19.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 RLN32626.1 - 0.0023 17.8 0.1 0.03 14.2 0.0 2.3 2 0 0 2 2 2 1 Hypothetical methyltransferase MTS PF05175.14 RLN32626.1 - 0.0065 16.0 0.0 0.015 14.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 RLN32626.1 - 0.014 14.8 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_29 PF03141.16 RLN32626.1 - 0.023 13.3 0.2 0.041 12.4 0.0 1.4 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.20 RLN32626.1 - 0.025 13.9 0.1 0.044 13.1 0.1 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase CheR PF01739.18 RLN32626.1 - 0.032 13.7 0.0 1.6 8.2 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.17 RLN32626.1 - 0.047 13.2 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase SPX PF03105.19 RLN32628.1 - 9.6 6.0 6.9 13 5.6 6.9 1.2 1 0 0 1 1 1 0 SPX domain EF-hand_7 PF13499.6 RLN32629.1 - 2e-06 28.2 0.8 4.5e-06 27.0 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN32629.1 - 0.00027 20.3 0.1 0.0033 16.9 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RLN32629.1 - 0.00047 19.9 0.0 0.0047 16.7 0.0 2.7 2 1 0 2 2 2 1 EF-hand domain K-box PF01486.17 RLN32629.1 - 0.039 14.1 1.2 0.082 13.1 0.3 2.0 2 0 0 2 2 2 0 K-box region Mntp PF02659.15 RLN32629.1 - 0.32 10.7 3.6 0.67 9.7 2.6 2.0 2 0 0 2 2 2 0 Putative manganese efflux pump FUSC_2 PF13515.6 RLN32629.1 - 3.9 7.6 13.6 8.2 6.6 12.3 2.2 1 1 1 2 2 2 0 Fusaric acid resistance protein-like EF-hand_1 PF00036.32 RLN32630.1 - 8.3e-13 46.9 2.1 8.3e-06 25.0 0.3 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RLN32630.1 - 1.7e-11 44.4 1.0 4.5e-11 43.0 0.4 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN32630.1 - 8e-09 34.7 0.0 0.0017 18.2 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RLN32630.1 - 6e-07 28.7 1.4 0.012 15.0 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 RLN32630.1 - 6.3e-06 25.9 2.5 0.0055 16.5 0.2 3.0 3 0 0 3 3 3 2 EF-hand domain pair DUF1925 PF09094.11 RLN32630.1 - 0.017 15.4 0.2 0.23 11.8 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1925) FUSC PF04632.12 RLN32630.1 - 0.57 8.7 13.0 0.94 7.9 10.2 2.4 1 1 1 2 2 2 0 Fusaric acid resistance protein family Pex19 PF04614.12 RLN32631.1 - 0.035 13.9 1.7 0.12 12.2 0.8 1.9 2 0 0 2 2 2 0 Pex19 protein family DUF3206 PF11472.8 RLN32631.1 - 0.044 13.8 0.1 0.093 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) Nup54 PF13874.6 RLN32631.1 - 0.055 13.6 0.4 0.1 12.7 0.4 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 BCIP PF13862.6 RLN32631.1 - 0.076 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 p21-C-terminal region-binding protein SF3b1 PF08920.10 RLN32632.1 - 1.6e-39 135.1 26.6 4.6e-39 133.6 1.8 4.6 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 RLN32632.1 - 6.3e-09 36.2 3.2 0.091 13.3 0.0 7.3 7 1 1 8 8 7 2 HEAT-like repeat HEAT PF02985.22 RLN32632.1 - 7.1e-08 32.1 6.7 4.6 7.8 0.1 9.2 10 0 0 10 10 10 1 HEAT repeat HEAT_2 PF13646.6 RLN32632.1 - 7.8e-08 32.6 5.6 0.11 12.9 0.0 6.9 6 2 2 8 8 8 3 HEAT repeats UME PF08064.13 RLN32632.1 - 0.0042 17.0 0.7 30 4.6 0.0 5.7 6 1 1 7 7 7 0 UME (NUC010) domain RTP1_C1 PF10363.9 RLN32632.1 - 0.0045 17.1 0.7 3.3 7.9 0.0 4.2 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 RLN32632.1 - 0.015 15.4 0.0 10 6.3 0.0 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.10 RLN32632.1 - 0.029 14.2 0.1 0.43 10.3 0.0 2.8 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) NUC173 PF08161.12 RLN32632.1 - 0.057 13.1 0.3 4.8 6.8 0.0 4.2 4 2 1 5 5 5 0 NUC173 domain UNC45-central PF11701.8 RLN32632.1 - 0.087 12.8 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central DivIC PF04977.15 RLN32632.1 - 5.9 6.7 6.3 13 5.6 6.3 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF1336 PF07059.12 RLN32634.1 - 1.2e-60 205.4 0.0 3.3e-60 204.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1336) START PF01852.19 RLN32634.1 - 2.9e-13 49.7 0.1 5.9e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 START domain PH PF00169.29 RLN32634.1 - 5.5e-07 30.1 0.3 7.1e-06 26.5 0.1 2.6 2 0 0 2 2 2 1 PH domain DUF3040 PF11239.8 RLN32634.1 - 1.7 9.0 7.0 0.6 10.4 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) ABC2_membrane PF01061.24 RLN32635.1 - 2.5e-54 183.9 60.3 1.2e-27 96.7 25.5 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN32635.1 - 1.3e-14 54.9 0.0 2.1e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 RLN32635.1 - 2.7e-11 43.2 41.6 3.6e-06 26.3 2.8 3.6 2 2 1 3 3 3 2 ABC-2 family transporter protein PDR_assoc PF08370.11 RLN32635.1 - 1.1e-06 28.2 11.7 0.0003 20.5 0.0 3.8 3 0 0 3 3 3 2 Plant PDR ABC transporter associated PDR_CDR PF06422.12 RLN32635.1 - 1.8e-06 27.7 1.3 0.0015 18.4 0.1 3.3 3 0 0 3 3 2 2 CDR ABC transporter AAA_21 PF13304.6 RLN32635.1 - 5.4e-05 23.1 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN32635.1 - 0.0025 17.8 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN32635.1 - 0.0027 17.4 0.3 0.0063 16.2 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN32635.1 - 0.0064 17.0 0.0 0.023 15.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN32635.1 - 0.0074 16.7 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 RLN32635.1 - 0.017 15.6 0.0 0.032 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 RLN32635.1 - 0.047 12.5 0.1 0.073 11.9 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_22 PF13401.6 RLN32635.1 - 0.08 13.2 0.1 0.21 11.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RLN32635.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 RLN32635.1 - 0.16 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 RLN32635.1 - 0.21 11.3 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 RLN32635.1 - 0.23 10.9 0.1 11 5.4 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Cyc-maltodext_C PF10438.9 RLN32636.1 - 1.4 9.0 4.2 1.9 8.6 1.0 2.9 2 0 0 2 2 2 0 Cyclo-malto-dextrinase C-terminal domain Pkinase_Tyr PF07714.17 RLN32638.1 - 6.4e-62 209.2 0.0 7.1e-37 127.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN32638.1 - 4.3e-54 183.6 0.0 1.2e-32 113.4 0.0 2.9 3 1 0 3 3 3 2 Protein kinase domain APH PF01636.23 RLN32638.1 - 0.0015 18.5 0.3 1.9 8.4 0.1 2.7 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 RLN32638.1 - 0.0029 17.0 0.0 1.1 8.5 0.0 2.4 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 RLN32638.1 - 0.005 16.5 0.1 0.39 10.3 0.0 2.6 3 0 0 3 3 3 1 RIO1 family RPW8 PF05659.11 RLN32638.1 - 0.036 13.8 0.0 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Seadorna_VP7 PF07387.11 RLN32638.1 - 0.11 11.5 0.6 0.18 10.9 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 DUF3813 PF12758.7 RLN32639.1 - 0.0026 18.0 2.4 4.1 7.8 0.1 3.7 1 1 2 3 3 3 3 Protein of unknown function (DUF3813) Coat_F PF07875.12 RLN32639.1 - 0.0088 16.2 5.4 4 7.7 0.3 4.1 4 0 0 4 4 4 1 Coat F domain DUF962 PF06127.11 RLN32641.1 - 5.7e-26 90.4 3.0 7.9e-26 90.0 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) DUF962 PF06127.11 RLN32642.1 - 1.4e-25 89.2 0.3 4.1e-25 87.7 0.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) RecO_C PF02565.15 RLN32642.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 1 0 1 1 1 0 Recombination protein O C terminal Pkinase PF00069.25 RLN32643.1 - 5.4e-50 170.2 0.0 8.1e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN32643.1 - 1.7e-42 145.5 0.0 2.3e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 RLN32643.1 - 8.8e-08 31.8 5.0 0.00019 21.2 1.7 2.9 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 RLN32643.1 - 6.8e-06 26.3 10.5 0.003 17.9 0.7 4.1 1 1 4 5 5 5 3 Leucine Rich repeats (2 copies) Protocadherin PF08374.11 RLN32643.1 - 0.00016 21.7 0.0 0.00034 20.7 0.0 1.5 1 0 0 1 1 1 1 Protocadherin TMEM154 PF15102.6 RLN32643.1 - 0.00076 19.4 0.1 0.00076 19.4 0.1 2.2 3 0 0 3 3 1 1 TMEM154 protein family EphA2_TM PF14575.6 RLN32643.1 - 0.0019 19.0 0.0 0.0056 17.5 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 RLN32643.1 - 0.0039 16.9 1.0 0.0098 15.6 1.0 1.6 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Insulin_TMD PF17870.1 RLN32643.1 - 0.0061 16.6 2.3 0.016 15.3 2.3 1.6 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment Ly49 PF08391.10 RLN32643.1 - 0.0075 16.6 0.1 0.016 15.6 0.1 1.4 1 0 0 1 1 1 1 Ly49-like protein, N-terminal region Mid2 PF04478.12 RLN32643.1 - 0.011 15.5 0.5 0.022 14.6 0.5 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Vpu PF00558.19 RLN32643.1 - 0.014 15.1 1.4 0.031 14.0 1.4 1.5 1 0 0 1 1 1 0 Vpu protein Chordopox_A13L PF05961.11 RLN32643.1 - 0.015 15.5 0.2 0.054 13.7 0.1 1.9 2 0 0 2 2 2 0 Chordopoxvirus A13L protein DUF202 PF02656.15 RLN32643.1 - 0.016 15.6 0.2 0.066 13.7 0.1 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF202) Orf78 PF06024.12 RLN32643.1 - 0.019 15.3 0.3 0.048 14.0 0.0 1.8 2 0 0 2 2 2 0 Orf78 (ac78) DUF5305 PF17231.2 RLN32643.1 - 0.022 14.2 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Saf_2TM PF18303.1 RLN32643.1 - 0.073 12.7 0.1 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF5385 PF17359.2 RLN32643.1 - 0.093 12.3 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Amnionless PF14828.6 RLN32643.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Amnionless LRR_1 PF00560.33 RLN32643.1 - 0.11 13.1 3.5 0.85 10.4 0.1 3.5 3 0 0 3 3 2 0 Leucine Rich Repeat RIFIN PF02009.16 RLN32643.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Rifin DUF4059 PF13268.6 RLN32643.1 - 0.14 12.6 0.2 0.31 11.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4059) Syndecan PF01034.20 RLN32643.1 - 0.2 11.6 0.2 0.5 10.3 0.2 1.6 1 0 0 1 1 1 0 Syndecan domain Phage_Coat_B PF05356.11 RLN32643.1 - 0.39 10.6 3.2 1.2 9.1 3.2 1.9 1 0 0 1 1 1 0 Phage Coat protein B SR-25 PF10500.9 RLN32643.1 - 0.68 9.5 2.8 1.2 8.6 2.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 RLN32644.1 - 9.2e-50 169.4 0.0 1.3e-49 168.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN32644.1 - 1.3e-41 142.6 0.0 1.8e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TMEM154 PF15102.6 RLN32644.1 - 0.00022 21.1 0.1 0.0005 20.0 0.1 1.5 1 0 0 1 1 1 1 TMEM154 protein family DUF202 PF02656.15 RLN32644.1 - 0.0023 18.4 0.0 0.0084 16.5 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Amnionless PF14828.6 RLN32644.1 - 0.0024 16.8 0.1 0.004 16.0 0.1 1.3 1 0 0 1 1 1 1 Amnionless SKG6 PF08693.10 RLN32644.1 - 0.0028 17.0 3.5 0.0072 15.7 3.5 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Protocadherin PF08374.11 RLN32644.1 - 0.0038 17.2 0.0 0.0066 16.4 0.0 1.3 1 0 0 1 1 1 1 Protocadherin Mid2 PF04478.12 RLN32644.1 - 0.0041 17.0 0.1 0.0086 15.9 0.1 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Rax2 PF12768.7 RLN32644.1 - 0.0043 16.5 0.1 0.0092 15.5 0.1 1.5 1 0 0 1 1 1 1 Cortical protein marker for cell polarity EphA2_TM PF14575.6 RLN32644.1 - 0.0066 17.3 0.0 0.018 15.9 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM132D_C PF15706.5 RLN32644.1 - 0.0093 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF1180 PF06679.12 RLN32644.1 - 0.012 16.1 1.1 0.034 14.6 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) APH PF01636.23 RLN32644.1 - 0.021 14.8 0.1 6 6.7 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIFIN PF02009.16 RLN32644.1 - 0.033 14.1 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 Rifin TMEM51 PF15345.6 RLN32644.1 - 0.074 12.9 0.4 0.13 12.1 0.4 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 DUF4366 PF14283.6 RLN32644.1 - 0.082 13.0 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Plasmodium_Vir PF05795.11 RLN32644.1 - 0.12 11.7 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein stn_TNFRSF12A PF12191.8 RLN32644.1 - 0.14 12.4 0.3 0.75 10.0 0.0 2.1 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain EssA PF10661.9 RLN32644.1 - 8.3 6.2 5.6 16 5.3 1.2 2.2 1 1 1 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA HTH_Tnp_4 PF13613.6 RLN32645.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HisKA_7TM PF16927.5 RLN32646.1 - 0.086 12.9 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 N-terminal 7TM region of histidine kinase MT0933_antitox PF14013.6 RLN32647.1 - 0.045 14.1 36.0 0.4 11.0 5.3 5.5 2 1 3 5 5 5 0 MT0933-like antitoxin protein YkyB PF14177.6 RLN32647.1 - 0.1 12.9 4.0 3.6 7.9 0.2 2.8 1 1 2 3 3 3 0 YkyB-like protein GET2 PF08690.10 RLN32647.1 - 2.2 7.9 11.7 25 4.4 11.7 1.9 1 1 0 1 1 1 0 GET complex subunit GET2 GTPase_binding PF09027.10 RLN32647.1 - 4.3 7.4 10.2 78 3.4 0.3 4.1 2 1 2 4 4 4 0 GTPase binding zf-RING_2 PF13639.6 RLN32657.1 - 7.9e-09 35.7 9.2 2e-08 34.5 9.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RLN32657.1 - 1.7e-07 31.0 6.0 3.6e-07 29.9 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN32657.1 - 3.6e-07 30.4 5.7 9.2e-07 29.1 5.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RLN32657.1 - 4.8e-07 29.5 8.3 1.1e-06 28.4 8.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN32657.1 - 3.7e-06 26.7 9.4 7.6e-06 25.7 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RLN32657.1 - 2.7e-05 24.1 3.6 6.2e-05 23.0 3.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 RLN32657.1 - 6.2e-05 22.8 8.7 0.00012 21.9 7.2 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 RLN32657.1 - 7.5e-05 22.7 5.3 0.00013 21.9 1.3 2.9 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN32657.1 - 0.0055 16.6 10.5 0.046 13.7 10.9 2.3 1 1 1 2 2 2 1 zinc-RING finger domain PX PF00787.24 RLN32657.1 - 0.044 13.8 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 PX domain Zn_ribbon_17 PF17120.5 RLN32657.1 - 0.053 13.2 6.2 0.16 11.6 6.2 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 RLN32657.1 - 0.53 10.1 5.0 1.7 8.5 1.7 2.7 2 1 0 2 2 2 0 RING-like zinc finger zf-RING_10 PF16685.5 RLN32657.1 - 0.59 10.3 5.4 4.8 7.4 3.9 2.5 2 0 0 2 2 2 0 zinc RING finger of MSL2 Rad50_zn_hook PF04423.14 RLN32657.1 - 0.64 9.9 5.2 3.7 7.5 0.6 2.8 2 1 1 3 3 3 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 RLN32657.1 - 4 7.3 13.0 0.37 10.6 7.4 2.2 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 RLN32657.1 - 8.1 6.7 10.7 10 6.4 8.5 2.3 2 0 0 2 2 2 0 RING-variant domain Ion_trans PF00520.31 RLN32658.1 - 5.4e-38 130.6 43.3 3.6e-20 72.2 14.9 2.1 2 0 0 2 2 2 2 Ion transport protein MPS2 PF17060.5 RLN32658.1 - 0.049 12.9 1.9 0.11 11.7 1.9 1.5 1 0 0 1 1 1 0 Monopolar spindle protein 2 PRIMA1 PF16101.5 RLN32658.1 - 0.16 12.0 0.3 5 7.2 0.1 2.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 UPF0542 PF15086.6 RLN32658.1 - 3.6 7.6 8.4 19 5.3 0.1 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0542 LmjF365940-deam PF14421.6 RLN32659.1 - 3.4e-64 216.0 3.3 8.7e-64 214.7 3.3 1.6 1 1 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases dCMP_cyt_deam_1 PF00383.23 RLN32659.1 - 0.12 12.2 0.0 5.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region CRAL_TRIO PF00650.20 RLN32700.1 - 3.5e-35 121.1 0.0 4.8e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 RLN32700.1 - 0.012 15.8 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain N6-adenineMlase PF10237.9 RLN32701.1 - 1.7e-35 122.2 0.0 2.2e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase PTEN_C2 PF10409.9 RLN32702.1 - 1.9e-09 37.4 0.0 2.7e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 RLN32702.1 - 1.8e-06 27.8 0.1 3.3e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RLN32702.1 - 0.00021 20.9 0.0 0.00035 20.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RLN32702.1 - 0.0028 17.7 0.1 0.005 16.8 0.1 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPn PF14671.6 RLN32702.1 - 0.049 14.1 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.6 RLN32702.1 - 0.057 13.5 0.0 0.14 12.3 0.0 1.6 2 0 0 2 2 2 0 Inositol hexakisphosphate BRK PF07533.16 RLN32702.1 - 0.063 12.9 0.2 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 BRK domain Metallophos PF00149.28 RLN32703.1 - 3e-41 142.2 0.1 4e-41 141.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RLN32703.1 - 3.2e-21 75.5 0.3 7.8e-21 74.3 0.1 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain NAD_kinase PF01513.21 RLN32722.1 - 4.7 6.3 5.2 0.73 9.0 0.4 2.1 2 1 0 2 2 2 0 ATP-NAD kinase PX PF00787.24 RLN32723.1 - 0.034 14.1 0.0 0.067 13.2 0.0 1.6 1 1 0 1 1 1 0 PX domain LAMTOR PF15454.6 RLN32723.1 - 0.051 14.2 0.0 0.14 12.8 0.0 1.7 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator FMN_red PF03358.15 RLN32724.1 - 6.6e-12 45.4 0.0 8.4e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 RLN32724.1 - 6.5e-07 29.3 0.0 8.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 RLN32724.1 - 1.5e-05 25.2 0.0 2.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 RLN32724.1 - 0.033 14.4 0.0 0.55 10.5 0.0 2.1 1 1 1 2 2 2 0 Flavodoxin domain YjgF_endoribonc PF14588.6 RLN32726.1 - 1.8e-26 93.0 0.0 2.1e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 RLN32726.1 - 2.8e-17 62.9 0.0 4.5e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP PI3_PI4_kinase PF00454.27 RLN32727.1 - 5.9e-31 108.2 0.0 1.1e-30 107.2 0.0 1.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Apyrase PF06079.11 RLN32727.1 - 0.086 12.0 0.0 1.4 8.1 0.1 2.0 2 0 0 2 2 2 0 Apyrase NT5C PF06941.12 RLN32728.1 - 4.6e-06 26.6 0.0 7.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Alba PF01918.21 RLN32728.1 - 8.1e-06 25.6 0.2 2.9e-05 23.8 0.3 1.8 2 0 0 2 2 2 1 Alba SET PF00856.28 RLN32729.1 - 1.3e-05 25.7 0.1 0.0038 17.6 0.1 2.4 1 1 0 1 1 1 1 SET domain FMN_red PF03358.15 RLN32730.1 - 8.3e-12 45.1 0.0 1.2e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 RLN32730.1 - 6.1e-09 35.9 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 RLN32730.1 - 2.3e-05 24.6 0.2 6.5e-05 23.2 0.2 1.8 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 RLN32730.1 - 0.0041 17.4 0.1 0.19 12.0 0.0 2.3 1 1 1 2 2 2 1 Flavodoxin domain FMN_red PF03358.15 RLN32731.1 - 5.9e-11 42.3 0.0 8.9e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 RLN32731.1 - 3e-08 33.6 0.0 3.8e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 RLN32731.1 - 0.17 12.2 0.0 0.42 10.8 0.0 1.7 1 1 1 2 2 2 0 Flavodoxin domain Ank_4 PF13637.6 RLN32732.1 - 5.8e-11 42.7 0.0 1.1e-09 38.6 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 RLN32732.1 - 1.1e-09 38.3 0.1 3.5e-05 24.1 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 RLN32732.1 - 3e-09 37.4 0.1 2e-08 34.7 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN32732.1 - 4.8e-07 29.9 0.0 0.00023 21.4 0.1 3.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN32732.1 - 0.00014 22.0 0.0 0.0023 18.3 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat S-methyl_trans PF02574.16 RLN32733.1 - 1.1e-44 153.2 0.0 1.3e-44 153.0 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase ANAPC4_WD40 PF12894.7 RLN32734.1 - 6.9e-11 42.3 4.7 0.028 14.7 0.0 5.7 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 RLN32734.1 - 6.7e-08 32.0 1.2 0.0098 15.0 0.0 3.6 3 1 1 4 4 4 2 Coatomer WD associated region Clathrin PF00637.20 RLN32734.1 - 2.6e-05 24.1 4.8 0.031 14.1 0.2 4.4 2 1 2 4 4 4 2 Region in Clathrin and VPS TPR_7 PF13176.6 RLN32734.1 - 0.00026 20.8 10.5 0.44 10.7 0.0 6.9 4 3 3 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN32734.1 - 0.00034 20.8 6.1 0.36 11.1 0.0 4.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN32734.1 - 0.00097 19.8 11.7 2.5 9.2 0.1 6.5 6 1 1 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN32734.1 - 0.0053 17.0 14.9 0.79 10.0 0.4 5.3 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 RLN32734.1 - 0.013 16.0 11.8 0.17 12.4 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.32 RLN32734.1 - 0.015 16.2 3.4 4.1 8.4 0.0 5.0 5 0 0 5 5 5 0 WD domain, G-beta repeat TPR_1 PF00515.28 RLN32734.1 - 0.018 14.8 11.2 0.58 10.1 0.2 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN32734.1 - 0.52 10.6 24.1 0.27 11.4 0.2 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat zf-RING_4 PF14570.6 RLN32734.1 - 3.6 7.4 13.7 2.4 8.0 8.1 2.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain TPR_16 PF13432.6 RLN32734.1 - 8.9 7.1 16.2 4 8.2 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc13p PF05839.11 RLN32735.1 - 0.11 12.6 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Apc13p protein Blt1 PF12754.7 RLN32735.1 - 3.3 8.0 8.5 12 6.2 1.8 2.6 1 1 0 2 2 2 0 Blt1 N-terminal domain PPR_2 PF13041.6 RLN32736.1 - 3.3e-18 65.6 2.0 1.8e-06 28.0 0.1 8.3 8 1 1 9 9 9 3 PPR repeat family PPR_3 PF13812.6 RLN32736.1 - 3.7e-16 59.0 0.0 3.1e-06 27.2 0.0 6.0 7 1 1 8 8 8 3 Pentatricopeptide repeat domain PPR_long PF17177.4 RLN32736.1 - 6.9e-14 51.7 6.5 0.086 12.2 0.0 6.0 2 1 3 5 5 5 5 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 RLN32736.1 - 6e-13 48.1 7.9 0.0013 18.9 0.1 7.9 9 0 0 9 9 9 3 PPR repeat TPR_14 PF13428.6 RLN32736.1 - 2.4 9.2 8.5 55 5.0 0.0 6.3 6 1 0 6 6 6 0 Tetratricopeptide repeat FMN_red PF03358.15 RLN32738.1 - 3.2e-13 49.7 0.0 4.1e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 RLN32738.1 - 9.2e-09 35.3 0.0 1.2e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 RLN32738.1 - 1.6e-05 25.1 0.1 3.4e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 Flavodoxin Flavodoxin_5 PF12724.7 RLN32738.1 - 0.0063 16.8 0.1 0.34 11.1 0.0 2.2 1 1 1 2 2 2 2 Flavodoxin domain FMN_red PF03358.15 RLN32739.1 - 7.2e-13 48.6 0.0 1.1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 RLN32739.1 - 1.4e-07 31.5 0.0 1.8e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 RLN32739.1 - 0.0011 19.2 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin S-methyl_trans PF02574.16 RLN32740.1 - 6.5e-51 173.7 0.0 7.4e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Cyt-b5 PF00173.28 RLN32741.1 - 2.6e-06 27.5 0.1 0.11 12.6 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Ank_2 PF12796.7 RLN32741.1 - 0.00024 21.6 0.0 0.00061 20.3 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN32741.1 - 0.0031 17.8 0.1 0.0077 16.5 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN32741.1 - 0.014 15.9 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN32741.1 - 0.035 14.7 0.0 0.11 13.1 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat Ank PF00023.30 RLN32741.1 - 0.1 13.1 0.0 0.3 11.6 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat His_Phos_1 PF00300.22 RLN32742.1 - 5.1e-21 75.3 0.1 4e-14 52.7 0.1 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) PPR_2 PF13041.6 RLN32743.1 - 2.3e-06 27.7 0.1 0.079 13.2 0.0 2.8 2 1 0 2 2 2 2 PPR repeat family Mad3_BUB1_II PF08171.11 RLN32743.1 - 0.00087 19.4 0.1 0.0016 18.5 0.1 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 MRP-S27 PF10037.9 RLN32743.1 - 0.0012 17.8 0.6 0.003 16.5 0.1 1.7 1 1 1 2 2 2 1 Mitochondrial 28S ribosomal protein S27 PPR_3 PF13812.6 RLN32743.1 - 0.025 14.6 0.2 0.1 12.7 0.1 2.0 2 0 0 2 2 2 0 Pentatricopeptide repeat domain RIC1 PF07064.13 RLN32744.1 - 0.0023 17.4 1.0 0.4 10.0 0.3 2.1 1 1 1 2 2 2 2 RIC1 TPR_10 PF13374.6 RLN32744.1 - 0.065 13.1 0.4 0.22 11.4 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 RLN32744.1 - 0.096 12.7 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 RLN32744.1 - 0.11 12.7 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein Astacin PF01400.24 RLN32745.1 - 3.1e-20 72.6 0.0 6.7e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Carn_acyltransf PF00755.20 RLN32746.1 - 3.3e-178 594.0 0.0 3.7e-178 593.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF3747 PF12565.8 RLN32747.1 - 0.004 16.5 0.0 0.011 15.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3747) Nsp2a_N PF17896.1 RLN32747.1 - 0.037 13.2 0.2 0.075 12.2 0.2 1.4 1 0 0 1 1 1 0 Replicase polyprotein 1a N-terminal domain Emaravirus_P4 PF16505.5 RLN32747.1 - 7.1 5.6 6.5 3.8 6.4 3.9 1.8 1 1 1 2 2 2 0 P4 movement protein of Emaravirus, and the 30K superfamily TMCO5 PF14992.6 RLN32748.1 - 2.2 7.8 32.0 0.03 13.9 22.4 2.3 2 0 0 2 2 2 0 TMCO5 family Peptidase_S74 PF13884.6 RLN32749.1 - 1.6e-15 57.1 0.0 3.2e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Chaperone of endosialidase TolA_bind_tri PF16331.5 RLN32749.1 - 0.29 11.3 4.3 0.68 10.0 1.8 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation TraB PF01963.17 RLN32751.1 - 0.069 13.0 1.4 0.18 11.7 1.4 1.6 1 0 0 1 1 1 0 TraB family Minor_capsid_3 PF12691.7 RLN32752.1 - 0.093 13.1 0.1 0.16 12.4 0.1 1.4 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage Glucan_synthase PF02364.15 RLN32754.1 - 8.5e-187 622.9 18.2 3.1e-164 548.3 12.4 3.3 1 1 2 3 3 3 2 1,3-beta-glucan synthase component TROVE PF05731.11 RLN32754.1 - 0.0086 15.2 0.1 2.6 7.0 0.0 2.3 2 0 0 2 2 2 2 TROVE domain Vma12 PF11712.8 RLN32755.1 - 0.55 10.3 3.2 1.3 9.1 3.2 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase FYVE PF01363.21 RLN32756.1 - 2.4e-10 40.4 9.2 2.4e-10 40.4 9.2 1.9 2 0 0 2 2 2 1 FYVE zinc finger zf-RING_5 PF14634.6 RLN32756.1 - 0.01 15.8 8.6 0.028 14.4 8.6 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 RLN32756.1 - 0.2 11.7 6.5 0.6 10.2 6.5 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 RLN32756.1 - 0.25 11.2 5.0 0.93 9.4 4.9 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 RLN32756.1 - 1.1 9.7 9.6 1.6 9.1 7.9 2.3 2 0 0 2 2 2 0 Ring finger domain Zn_ribbon_17 PF17120.5 RLN32756.1 - 2.6 7.7 10.5 0.047 13.3 2.8 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 RLN32756.1 - 6.7 6.7 8.0 18 5.3 8.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 RLN32757.1 - 7.3e-10 38.9 9.1 7.3e-10 38.9 9.1 2.6 2 0 0 2 2 2 1 FYVE zinc finger GAF PF01590.26 RLN32757.1 - 6.1e-07 30.1 0.2 2.6e-06 28.1 0.1 2.2 2 0 0 2 2 2 1 GAF domain zf-B_box PF00643.24 RLN32757.1 - 0.069 13.3 2.9 0.22 11.7 2.9 1.8 1 0 0 1 1 1 0 B-box zinc finger Prok-RING_4 PF14447.6 RLN32757.1 - 0.12 12.3 4.6 0.47 10.3 4.6 2.1 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FYVE_2 PF02318.16 RLN32757.1 - 0.14 12.4 11.5 0.51 10.6 6.0 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_2 PF13639.6 RLN32757.1 - 0.45 10.9 9.1 1.1 9.7 7.9 2.3 2 0 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.6 RLN32757.1 - 1.7 8.8 9.7 1.3 9.1 7.6 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 RLN32757.1 - 3 7.9 14.9 0.16 11.9 8.5 2.3 3 0 0 3 3 3 0 zinc-RING finger domain EGF_2 PF07974.13 RLN32758.1 - 6.9e-09 35.9 37.3 8.4e-05 22.9 4.8 3.4 3 0 0 3 3 3 3 EGF-like domain EGF_Tenascin PF18720.1 RLN32758.1 - 0.046 13.8 7.4 0.046 13.8 7.4 3.3 3 0 0 3 3 3 0 Tenascin EGF domain EGF PF00008.27 RLN32758.1 - 0.061 13.6 33.6 0.79 10.1 3.2 3.6 4 0 0 4 4 4 0 EGF-like domain Laminin_EGF PF00053.24 RLN32758.1 - 0.28 11.3 31.0 1.3 9.3 11.8 2.8 2 1 1 3 3 3 0 Laminin EGF domain Aldo_ket_red PF00248.21 RLN32762.1 - 8.6e-11 41.6 0.0 1.3e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase_Tyr PF07714.17 RLN32763.1 - 2.8e-36 125.1 0.0 3.4e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN32763.1 - 1.3e-35 123.0 0.0 1.9e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SID-1_RNA_chan PF13965.6 RLN32763.1 - 0.19 10.1 0.0 0.26 9.7 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 LZ_Tnp_IS66 PF13007.7 RLN32769.1 - 0.12 13.2 0.2 0.42 11.4 0.1 2.0 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain DUF2158 PF09926.9 RLN32769.1 - 0.14 11.9 0.0 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2158) zf-RING_4 PF14570.6 RLN32770.1 - 9.5e-08 31.7 7.7 1.9e-07 30.8 7.7 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 RLN32770.1 - 0.0011 18.7 0.0 0.0028 17.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 RLN32770.1 - 0.023 14.5 4.8 0.04 13.8 4.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Torus PF16131.5 RLN32770.1 - 0.3 11.8 3.0 0.21 12.3 0.2 2.2 2 0 0 2 2 2 0 Torus domain PAM2 PF07145.15 RLN32771.1 - 3.6e-06 26.3 2.6 0.0032 17.0 0.5 2.8 1 1 1 2 2 2 2 Ataxin-2 C-terminal region LsmAD PF06741.13 RLN32771.1 - 0.0035 17.9 0.5 0.0087 16.6 0.5 1.7 1 0 0 1 1 1 1 LsmAD domain Peptidase_M57 PF12388.8 RLN32771.1 - 0.6 9.7 4.4 8.2 6.0 0.1 2.4 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase SF-assemblin PF06705.11 RLN32772.1 - 0.02 14.2 13.2 0.038 13.3 6.2 2.4 2 0 0 2 2 2 0 SF-assemblin/beta giardin DUF4075 PF13294.6 RLN32772.1 - 0.17 12.1 0.9 1.6 8.9 0.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4075) Allexi_40kDa PF05549.11 RLN32772.1 - 0.58 9.6 12.0 0.049 13.2 2.1 2.9 2 1 1 3 3 3 0 Allexivirus 40kDa protein Fib_alpha PF08702.10 RLN32772.1 - 1.1 9.5 10.0 0.23 11.6 3.4 2.8 2 2 0 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 RLN32772.1 - 5.8 7.0 16.7 0.54 10.3 1.1 4.8 1 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus FYVE PF01363.21 RLN32773.1 - 8.7e-12 45.0 12.6 1.8e-11 44.0 12.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN32773.1 - 2.8e-05 24.3 4.9 6.3e-05 23.2 4.9 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger Prok-RING_2 PF14445.6 RLN32773.1 - 1.1 9.4 5.7 1 9.6 3.5 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 2 4HBT PF03061.22 RLN32775.1 - 1.4e-09 38.1 0.2 1.1e-05 25.7 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily MaoC_dehydratas PF01575.19 RLN32775.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain FYVE PF01363.21 RLN32776.1 - 4.2e-07 30.0 6.7 6.7e-07 29.3 6.7 1.3 1 0 0 1 1 1 1 FYVE zinc finger Arm PF00514.23 RLN32777.1 - 4.7e-07 29.6 0.1 1.3e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat T3SS_ExsE PF18286.1 RLN32777.1 - 0.099 12.6 0.0 5.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Type III secretion system ExsE PAS PF00989.25 RLN32778.1 - 1.7e-107 353.4 2.0 8.4e-20 70.9 0.0 6.5 6 0 0 6 6 6 6 PAS fold PAS_4 PF08448.10 RLN32778.1 - 6.8e-60 200.1 0.0 1.4e-12 47.8 0.0 6.7 6 0 0 6 6 6 6 PAS fold PAS_9 PF13426.7 RLN32778.1 - 2.3e-57 191.7 10.9 2.5e-10 40.5 0.0 7.0 7 0 0 7 7 7 6 PAS domain PAS_3 PF08447.12 RLN32778.1 - 1.3e-31 108.8 0.0 2.8e-07 30.7 0.0 6.3 6 0 0 6 6 6 5 PAS fold HATPase_c PF02518.26 RLN32778.1 - 7e-27 94.2 0.0 2.8e-26 92.2 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 RLN32778.1 - 4.9e-20 71.8 0.0 1.4e-19 70.3 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain PAS_8 PF13188.7 RLN32778.1 - 6e-17 61.2 0.1 0.03 14.3 0.0 5.7 5 0 0 5 5 5 5 PAS domain HisKA PF00512.25 RLN32778.1 - 7.7e-17 61.1 0.1 2.8e-16 59.3 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain EF-hand_1 PF00036.32 RLN32778.1 - 6.8e-10 37.8 6.6 4.4e-06 25.9 0.9 3.0 3 0 0 3 3 3 2 EF hand PAS_10 PF13596.6 RLN32778.1 - 1.2e-08 35.5 2.3 0.041 14.5 0.0 5.8 6 0 0 6 6 6 1 PAS domain EF-hand_8 PF13833.6 RLN32778.1 - 2.9e-08 33.4 3.3 2e-05 24.4 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 RLN32778.1 - 3.2e-08 33.9 3.0 0.0003 21.2 0.1 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN32778.1 - 2e-07 30.4 3.8 0.0052 16.6 0.3 3.5 3 0 0 3 3 3 2 EF-hand domain Hpt PF01627.23 RLN32778.1 - 1.8e-06 28.1 0.1 5.4e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 Hpt domain EF-hand_5 PF13202.6 RLN32778.1 - 2.4e-05 23.6 10.7 0.01 15.3 1.4 3.2 3 0 0 3 3 3 2 EF hand PAS_7 PF12860.7 RLN32778.1 - 3.7e-05 23.9 7.5 0.18 12.0 0.1 6.4 6 3 0 6 6 6 1 PAS fold HlyD PF00529.20 RLN32778.1 - 0.35 10.8 1.6 10 6.1 0.0 3.7 5 0 0 5 5 4 0 HlyD membrane-fusion protein of T1SS HTH_23 PF13384.6 RLN32779.1 - 0.0021 17.8 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 RLN32779.1 - 0.007 16.4 1.3 0.047 13.7 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn helix Phage_NinH PF06322.11 RLN32779.1 - 0.083 12.8 0.0 8.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Phage NinH protein Gp_dh_N PF00044.24 RLN32780.1 - 2e-39 134.0 0.2 3.4e-39 133.2 0.2 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 RLN32780.1 - 7.9e-05 22.8 0.7 0.00051 20.2 0.5 2.1 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 RLN32780.1 - 0.022 14.7 0.1 0.064 13.2 0.0 1.7 1 1 1 2 2 2 0 Zinc-binding dehydrogenase MOSP_N PF02707.16 RLN32780.1 - 0.048 13.4 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Major Outer Sheath Protein N-terminal region 2-Hacid_dh_C PF02826.19 RLN32780.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 RLN32781.1 - 1e-69 233.2 0.0 1.2e-69 233.0 0.0 1.0 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Pirin PF02678.16 RLN32793.1 - 1.5e-19 70.0 0.0 2.4e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Pirin Ank_2 PF12796.7 RLN32794.1 - 4.1e-111 363.8 16.2 3.1e-15 56.5 0.1 8.6 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 RLN32794.1 - 3.7e-91 295.9 23.3 3.4e-06 27.2 0.0 15.5 16 0 0 16 16 15 15 Ankyrin repeat Ank_3 PF13606.6 RLN32794.1 - 2.4e-87 276.3 16.4 1.9e-06 27.7 0.0 16.0 16 0 0 16 16 16 15 Ankyrin repeat Ank_4 PF13637.6 RLN32794.1 - 2.3e-81 267.2 25.0 1.2e-09 38.5 0.1 13.0 4 4 8 13 13 13 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN32794.1 - 2.7e-75 247.4 35.5 1.7e-08 34.5 0.2 13.4 1 1 12 14 14 14 14 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 RLN32794.1 - 1.9e-40 138.8 0.0 2.9e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN32794.1 - 5.3e-38 130.9 0.0 8.7e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Nepo_coat_C PF03688.14 RLN32794.1 - 0.0088 15.9 1.9 9.3 6.1 0.1 4.6 2 1 1 5 5 5 1 Nepovirus coat protein, C-terminal domain tRNA_NucTran2_2 PF13735.6 RLN32794.1 - 0.024 14.6 0.3 7.9 6.5 0.0 2.9 2 0 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative YlzJ PF14035.6 RLN32794.1 - 0.054 13.7 0.0 2.6e+02 1.9 0.0 5.2 6 0 0 6 6 5 0 YlzJ-like protein MEDS PF14417.6 RLN32794.1 - 0.057 13.3 1.9 17 5.2 0.1 4.0 2 1 2 4 4 4 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Imm_superinfect PF14373.6 RLN32794.1 - 1.1 9.3 15.6 21 5.1 0.0 8.4 11 0 0 11 11 11 0 Superinfection immunity protein VWA_3_C PF18571.1 RLN32794.1 - 6.8 6.6 12.9 1.9e+02 2.0 0.0 7.3 10 0 0 10 10 10 0 von Willebrand factor type A C-terminal domain Lectin_leg-like PF03388.13 RLN32795.1 - 7.2e-36 123.7 0.1 1e-35 123.2 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 RLN32795.1 - 3.5e-09 37.0 0.3 6.5e-09 36.1 0.3 1.4 1 1 0 1 1 1 1 Bacterial lectin Sugar_tr PF00083.24 RLN32799.1 - 4.5e-14 52.2 0.0 4.8e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter ABC_membrane PF00664.23 RLN32800.1 - 4.9e-50 170.7 21.8 6.3e-28 98.2 7.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN32800.1 - 5.9e-48 162.9 0.0 7.9e-28 97.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN32800.1 - 9.8e-12 44.8 0.4 6.3e-05 22.5 0.1 3.8 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RLN32800.1 - 4.6e-05 23.5 0.0 0.031 14.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase IstB_IS21 PF01695.17 RLN32800.1 - 0.0011 18.7 0.2 1.2 8.9 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 RLN32800.1 - 0.004 17.1 1.0 2 8.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 RLN32800.1 - 0.005 17.2 0.0 2.7 8.4 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 RLN32800.1 - 0.012 16.1 0.0 9.5 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 RLN32800.1 - 0.046 13.5 0.4 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN32800.1 - 0.067 13.5 1.6 11 6.3 0.1 2.8 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 RLN32800.1 - 0.082 13.0 2.4 0.12 12.4 0.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_21 PF13304.6 RLN32800.1 - 0.083 12.7 0.0 8.2 6.1 0.1 2.7 2 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF1150 PF06620.11 RLN32800.1 - 0.12 12.5 2.1 11 6.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1150) DEAD PF00270.29 RLN32800.1 - 0.19 11.5 0.7 1 9.1 0.6 2.2 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_23 PF13476.6 RLN32800.1 - 0.25 11.8 0.0 1.7 9.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 RLN32800.1 - 0.62 10.1 4.5 2.5 8.1 0.2 2.6 2 1 0 2 2 2 0 Dynamin family Filament PF00038.21 RLN36522.1 - 0.79 9.2 23.4 0.13 11.8 0.2 3.0 2 1 1 3 3 3 0 Intermediate filament protein UPF0242 PF06785.11 RLN36522.1 - 1.9 8.5 6.1 8.1 6.5 3.9 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 RLN36522.1 - 4.5 6.1 17.4 18 4.1 0.1 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein OTU PF02338.19 RLN36552.1 - 4.3e-14 53.1 0.0 1e-13 51.9 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 RLN36552.1 - 0.00018 21.0 0.0 0.28 10.6 0.0 2.7 2 0 0 2 2 2 2 Peptidase C65 Otubain HIP1_clath_bdg PF16515.5 RLN36552.1 - 1.4 9.6 27.3 0.77 10.4 3.5 4.4 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-RING_2 PF13639.6 RLN36553.1 - 5.2e-10 39.5 12.2 8.4e-10 38.8 12.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN36553.1 - 4.7e-08 32.7 13.3 7.8e-08 32.0 13.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN36553.1 - 9e-07 29.1 13.6 4.2e-06 27.0 13.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RLN36553.1 - 2.2e-05 24.3 12.8 3.9e-05 23.4 12.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 RLN36553.1 - 0.00013 22.0 5.2 0.00022 21.3 5.2 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_3 PF13920.6 RLN36553.1 - 0.00031 20.5 9.7 0.00047 20.0 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN36553.1 - 0.00073 19.5 8.6 0.0016 18.4 8.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 RLN36553.1 - 0.0013 18.7 3.3 0.0025 17.8 3.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 RLN36553.1 - 0.0024 17.4 8.5 0.0046 16.5 8.5 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 RLN36553.1 - 0.0041 16.8 7.3 0.0041 16.8 7.3 2.0 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_5 PF14634.6 RLN36553.1 - 0.01 15.8 10.8 0.017 15.1 10.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 RLN36553.1 - 0.094 12.6 9.9 0.18 11.7 9.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 UPF0547 PF10571.9 RLN36553.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 FANCL_C PF11793.8 RLN36553.1 - 0.14 12.4 7.5 0.66 10.2 7.5 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 RLN36553.1 - 1.1 9.6 9.5 2.1 8.7 9.5 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 RLN36553.1 - 3.7 7.7 10.1 7.9 6.7 10.1 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 RLN36553.1 - 9.5 6.1 9.1 33 4.4 9.1 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Neurochondrin PF05536.11 RLN36554.1 - 5.8e-10 38.2 0.1 7.3e-09 34.5 0.0 1.9 2 0 0 2 2 2 2 Neurochondrin Neurochondrin PF05536.11 RLN36555.1 - 5.6e-26 91.1 3.4 1.1e-25 90.1 3.0 1.6 2 0 0 2 2 2 1 Neurochondrin UFD1 PF03152.14 RLN36558.1 - 0.031 13.8 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 XRN_N PF03159.18 RLN36558.1 - 1.1 8.6 4.8 1.4 8.2 4.8 1.1 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus EURL PF06937.11 RLN36558.1 - 3.8 6.9 7.3 4.6 6.6 7.3 1.1 1 0 0 1 1 1 0 EURL protein Beach PF02138.18 RLN36561.1 - 1.1e-120 402.1 0.0 1.9e-120 401.4 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain Peptidase_M8 PF01457.16 RLN36561.1 - 5.1e-82 276.3 3.3 8.7e-82 275.5 3.3 1.3 1 0 0 1 1 1 1 Leishmanolysin Ank_5 PF13857.6 RLN36561.1 - 1.1e-23 82.9 2.3 1.2e-08 35.1 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN36561.1 - 8.5e-21 74.3 0.4 1.4e-11 44.8 0.1 3.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN36561.1 - 1.1e-19 70.6 0.1 1.7e-06 28.5 0.0 6.8 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN36561.1 - 1.1e-12 47.8 6.5 0.0033 17.8 0.0 5.3 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 RLN36561.1 - 8.5e-12 44.2 0.3 0.011 16.2 0.0 5.0 4 0 0 4 4 3 3 Ankyrin repeat WD40 PF00400.32 RLN36561.1 - 3.7e-08 33.9 1.7 0.071 14.0 0.1 4.5 3 0 0 3 3 3 2 WD domain, G-beta repeat PH_BEACH PF14844.6 RLN36561.1 - 0.00037 20.6 0.0 0.001 19.1 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 RLN36561.1 - 0.0036 17.5 0.0 0.0036 17.5 0.0 3.1 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily DUF3741 PF12552.8 RLN36561.1 - 0.02 14.8 0.0 0.071 13.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) EGF_Tenascin PF18720.1 RLN36561.1 - 0.11 12.5 10.7 1 9.5 10.7 2.9 1 0 0 1 1 1 0 Tenascin EGF domain EGF_2 PF07974.13 RLN36561.1 - 0.12 12.8 61.9 0.0077 16.6 12.1 5.7 5 0 0 5 5 5 0 EGF-like domain Nop14 PF04147.12 RLN36561.1 - 0.34 9.1 13.0 0.65 8.1 13.0 1.4 1 0 0 1 1 1 0 Nop14-like family DUF1387 PF07139.11 RLN36561.1 - 4 7.1 13.8 9.8 5.8 13.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Sulfate_transp PF00916.20 RLN36562.1 - 6e-20 71.3 16.4 9.9e-20 70.6 16.4 1.3 1 0 0 1 1 1 1 Sulfate permease family RraA-like PF03737.15 RLN36564.1 - 4.3e-31 108.1 5.1 6.1e-31 107.6 5.1 1.2 1 0 0 1 1 1 1 Aldolase/RraA zf-BED PF02892.15 RLN36564.1 - 1.9e-05 24.6 0.1 3.4e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 BED zinc finger Transpos_assoc PF13963.6 RLN36564.1 - 0.0032 17.7 0.0 0.13 12.6 0.1 2.2 2 0 0 2 2 2 1 Transposase-associated domain zf-C2H2_4 PF13894.6 RLN36564.1 - 0.76 10.8 2.1 1 10.4 0.2 2.3 2 1 1 3 3 3 0 C2H2-type zinc finger PBECR5 PF18814.1 RLN36579.1 - 3.3 7.6 10.9 7.9 6.3 10.9 1.6 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 EMP24_GP25L PF01105.24 RLN36580.1 - 6.1e-20 71.9 0.7 6.5e-20 71.8 0.7 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ank_2 PF12796.7 RLN36581.1 - 1.3e-33 115.4 15.2 1.7e-15 57.4 0.5 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN36581.1 - 2.4e-29 101.3 1.3 4.4e-08 33.5 0.0 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN36581.1 - 4.5e-27 93.7 9.0 1.5e-05 25.1 0.1 6.8 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 RLN36581.1 - 7.3e-24 83.1 13.4 6e-05 23.3 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 RLN36581.1 - 4.1e-19 66.7 6.1 0.0025 18.1 0.0 7.2 7 0 0 7 7 7 4 Ankyrin repeat Pkinase_Tyr PF07714.17 RLN36581.1 - 1.4e-18 67.1 0.0 6.5e-12 45.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN36581.1 - 2.5e-13 50.0 0.0 2.5e-09 36.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Cro PF09048.10 RLN36581.1 - 0.96 9.5 2.9 48 4.1 0.1 3.3 3 0 0 3 3 3 0 Cro Phage_int_SAM_5 PF13102.6 RLN36582.1 - 0.0018 18.6 0.3 0.005 17.2 0.1 1.7 2 0 0 2 2 2 1 Phage integrase SAM-like domain SRP54_N PF02881.19 RLN36582.1 - 0.037 14.2 0.1 0.097 12.9 0.1 1.8 1 1 0 1 1 1 0 SRP54-type protein, helical bundle domain TMF_TATA_bd PF12325.8 RLN36583.1 - 4.6e-24 84.9 12.4 4.6e-24 84.9 12.4 8.6 2 1 6 9 9 9 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 RLN36583.1 - 3e-07 30.4 13.1 3e-07 30.4 13.1 10.3 5 4 1 9 9 9 2 TATA element modulatory factor 1 DNA binding YqjK PF13997.6 RLN36583.1 - 0.2 12.0 6.5 3.7 7.9 0.4 3.7 2 0 0 2 2 2 0 YqjK-like protein GN3L_Grn1 PF08701.11 RLN36584.1 - 3.2e-17 62.4 20.5 3.2e-17 62.4 20.5 2.5 2 1 1 3 3 3 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 RLN36584.1 - 6.6e-14 52.0 0.2 6.4e-11 42.3 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN36584.1 - 5e-09 35.9 0.2 0.00039 20.0 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RLN36584.1 - 7.5e-06 26.0 0.3 0.064 13.2 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 RLN36584.1 - 9.8e-05 22.0 0.2 0.011 15.3 0.1 3.1 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 RLN36584.1 - 0.00035 21.0 6.0 0.00047 20.6 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain cobW PF02492.19 RLN36584.1 - 0.00083 19.0 0.4 0.068 12.8 0.0 2.7 2 1 1 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain Nuc_deoxyri_tr2 PF15891.5 RLN36584.1 - 0.0015 18.8 0.7 0.0049 17.2 0.7 2.0 1 1 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like MeaB PF03308.16 RLN36584.1 - 0.0016 17.5 0.0 0.0016 17.5 0.0 2.6 2 1 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 RLN36584.1 - 0.005 16.9 3.8 0.019 15.0 0.2 3.1 2 2 1 3 3 3 1 Dynamin family SRPRB PF09439.10 RLN36584.1 - 0.018 14.5 0.0 0.057 12.8 0.0 1.8 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 RLN36584.1 - 0.031 14.8 0.0 0.031 14.8 0.0 2.9 3 1 0 3 3 3 0 AAA domain Roc PF08477.13 RLN36584.1 - 0.044 14.0 0.0 1.6 9.0 0.0 2.9 3 1 1 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 RLN36584.1 - 0.068 13.7 0.3 0.88 10.1 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Arf PF00025.21 RLN36584.1 - 0.093 12.2 0.1 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_24 PF13479.6 RLN36584.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.16 RLN36584.1 - 0.12 11.6 0.6 1.2 8.5 0.0 2.6 2 1 1 3 3 3 0 AIG1 family DUF4407 PF14362.6 RLN36584.1 - 0.57 9.5 4.6 1.2 8.5 4.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 RLN36589.1 - 3.7e-56 190.4 0.0 5.6e-56 189.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN36589.1 - 2e-28 99.4 0.0 1e-27 97.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN36589.1 - 2e-05 23.5 2.6 3.4e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 RLN36589.1 - 0.00027 20.3 0.0 0.00068 19.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN36589.1 - 0.00034 20.6 0.6 0.044 13.7 0.2 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family TraK PF06586.11 RLN36589.1 - 0.0074 16.0 0.9 0.0074 16.0 0.9 2.3 2 0 0 2 2 2 1 TraK protein Kdo PF06293.14 RLN36589.1 - 0.022 14.1 0.3 0.041 13.2 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RLN36589.1 - 0.3 10.6 1.2 0.74 9.4 1.2 1.7 1 1 0 1 1 1 0 RIO1 family HSF_DNA-bind PF00447.17 RLN36590.1 - 1.1e-15 58.0 0.0 1.8e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding HSF_DNA-bind PF00447.17 RLN36591.1 - 4.5e-16 59.3 0.0 6.9e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding RasGEF PF00617.19 RLN36592.1 - 1.5e-30 106.7 0.0 3.9e-30 105.4 0.0 1.8 2 0 0 2 2 2 1 RasGEF domain Ank_2 PF12796.7 RLN36592.1 - 2.9e-30 104.7 3.2 2e-08 34.7 0.2 4.8 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN36592.1 - 4.6e-28 97.2 2.1 6.8e-08 32.9 0.2 6.5 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN36592.1 - 4.1e-26 90.7 6.8 1.4e-08 34.8 0.0 6.7 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 RLN36592.1 - 2.1e-22 78.5 12.7 0.00023 21.4 0.0 8.9 7 2 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 RLN36592.1 - 2.7e-22 76.4 5.0 0.00055 20.2 0.0 9.3 10 0 0 10 10 9 5 Ankyrin repeat VPS9 PF02204.18 RLN36592.1 - 1.1e-06 28.8 0.0 2.7e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PH PF00169.29 RLN36592.1 - 6.7e-06 26.6 0.0 1.5e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN36592.1 - 0.001 19.3 0.0 0.077 13.3 0.0 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain EccE PF11203.8 RLN36592.1 - 0.026 14.8 1.3 0.049 14.0 0.1 2.1 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE PDZ PF00595.24 RLN36592.1 - 0.053 13.9 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 PDZ domain EzrA PF06160.12 RLN36603.1 - 0.026 12.7 2.2 0.047 11.9 2.1 1.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Fez1 PF06818.15 RLN36603.1 - 0.036 14.5 2.7 0.14 12.6 2.2 2.1 1 1 1 2 2 2 0 Fez1 AATF-Che1 PF13339.6 RLN36603.1 - 0.21 12.3 1.9 0.54 10.9 1.9 1.7 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor GAS PF13851.6 RLN36603.1 - 0.5 9.7 10.6 0.13 11.6 2.3 2.9 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.11 RLN36603.1 - 0.97 9.7 5.5 6.1 7.2 0.3 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3450 PF11932.8 RLN36603.1 - 1.2 8.3 7.7 0.21 10.8 1.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Exonuc_VII_L PF02601.15 RLN36603.1 - 2.2 7.8 6.2 1.1 8.8 3.9 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit ApoL PF05461.11 RLN36603.1 - 2.5 7.3 14.5 6.1 6.1 12.8 2.3 1 1 1 2 2 2 0 Apolipoprotein L PhoU PF01895.19 RLN36603.1 - 3.1 8.3 6.1 5.1 7.6 0.2 3.1 3 1 1 4 4 4 0 PhoU domain DUF641 PF04859.12 RLN36603.1 - 3.2 8.1 8.3 0.14 12.5 1.0 2.3 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) Patatin PF01734.22 RLN36605.1 - 3.2e-11 43.8 0.1 2.2e-09 37.8 0.1 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase NrsF PF06532.11 RLN36605.1 - 0.014 15.1 0.2 0.014 15.1 0.2 2.3 2 0 0 2 2 2 0 Negative regulator of sigma F Na_Ca_ex PF01699.24 RLN36606.1 - 7.1e-33 113.7 29.2 3.3e-21 75.8 8.2 2.9 2 1 1 3 3 3 2 Sodium/calcium exchanger protein PH PF00169.29 RLN36607.1 - 6.4e-07 29.8 0.0 1.5e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN36607.1 - 0.036 14.5 0.0 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain DUF763 PF05559.11 RLN36607.1 - 0.038 13.2 0.2 0.064 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF763) PKD_channel PF08016.12 RLN36608.1 - 2.5e-32 112.1 11.3 3.8e-32 111.5 11.3 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 RLN36608.1 - 1e-08 34.7 15.2 1e-08 34.7 15.2 1.5 2 0 0 2 2 2 1 Ion transport protein START PF01852.19 RLN36609.1 - 4.4e-20 72.0 0.0 6.8e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 START domain FYVE PF01363.21 RLN36609.1 - 3e-18 65.7 11.8 5.5e-18 64.9 11.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN36609.1 - 0.013 15.7 5.3 0.024 14.9 5.3 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger IBR PF01485.21 RLN36609.1 - 0.04 14.1 4.1 0.098 12.9 4.1 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Tir_receptor_C PF07489.11 RLN36609.1 - 1.4 8.8 14.3 0.032 14.2 6.1 2.2 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus zf-CRD PF17979.1 RLN36609.1 - 2 8.5 9.5 8.3 6.5 9.5 2.0 1 1 0 1 1 1 0 Cysteine rich domain with multizinc binding regions zf-RING_5 PF14634.6 RLN36609.1 - 7.9 6.5 10.2 19 5.3 10.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain PH PF00169.29 RLN36610.1 - 9.1e-05 22.9 0.0 0.00015 22.2 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN36610.1 - 0.066 13.6 0.0 0.15 12.5 0.0 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain MFS_1 PF07690.16 RLN36611.1 - 1.2e-26 93.5 21.4 1.6e-26 93.1 21.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily RCC1 PF00415.18 RLN36612.1 - 8.8e-73 240.8 19.4 3.4e-13 50.0 0.1 8.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat SPRY PF00622.28 RLN36612.1 - 9.4e-34 116.1 0.9 1.2e-19 70.5 0.0 2.6 2 0 0 2 2 2 2 SPRY domain RCC1_2 PF13540.6 RLN36612.1 - 1.6e-31 107.5 37.0 4.7e-09 35.8 0.3 7.5 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 RLN36612.1 - 0.00027 20.5 0.1 0.7 9.3 0.1 2.3 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) DUF4203 PF13886.6 RLN36620.1 - 3.2e-29 102.0 8.5 3.6e-29 101.9 8.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF4131 PF13567.6 RLN36620.1 - 0.0075 15.9 5.6 0.36 10.5 0.6 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4131) Trp_oprn_chp PF09534.10 RLN36620.1 - 0.015 15.1 0.4 0.029 14.2 0.0 1.7 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ninjurin PF04923.12 RLN36620.1 - 0.041 13.8 0.2 0.11 12.5 0.2 1.6 2 0 0 2 2 2 0 Ninjurin DUF4381 PF14316.6 RLN36620.1 - 0.48 10.7 2.0 1.8 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF2157 PF09925.9 RLN36620.1 - 0.6 9.9 5.0 0.97 9.2 2.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF3180 PF11377.8 RLN36620.1 - 1.6 8.8 6.5 0.5 10.5 1.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3180) DUF1275 PF06912.11 RLN36620.1 - 3.9 7.3 9.3 87 2.9 9.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1275) DUF4203 PF13886.6 RLN36621.1 - 1.7e-44 151.9 36.9 2.6e-44 151.3 36.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Rpr2 PF04032.16 RLN36621.1 - 0.11 12.8 0.3 0.25 11.7 0.3 1.6 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain UPF0370 PF13980.6 RLN36621.1 - 0.16 12.0 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) Trp_oprn_chp PF09534.10 RLN36621.1 - 0.28 11.0 0.0 0.28 11.0 0.0 2.9 2 2 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4203 PF13886.6 RLN36622.1 - 7e-44 149.9 28.4 7e-44 149.9 28.4 1.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) DUF308 PF03729.13 RLN36622.1 - 0.081 13.3 0.6 0.081 13.3 0.6 4.5 4 1 1 5 5 5 0 Short repeat of unknown function (DUF308) ApoO PF09769.9 RLN36622.1 - 0.099 12.6 1.6 5.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Apolipoprotein O PorA PF11271.8 RLN36622.1 - 0.32 10.3 2.0 0.3 10.3 0.4 1.8 2 0 0 2 2 2 0 Porin PorA Tyrosinase PF00264.20 RLN36623.1 - 1.6e-09 38.4 0.0 1.6e-09 38.4 0.0 4.4 3 1 1 4 4 4 1 Common central domain of tyrosinase DUF4203 PF13886.6 RLN36624.1 - 8.1e-82 273.8 71.9 5.9e-44 150.2 33.4 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4203) DUF308 PF03729.13 RLN36624.1 - 0.028 14.8 0.8 0.028 14.8 0.8 7.1 4 2 4 8 8 8 0 Short repeat of unknown function (DUF308) Prominin PF05478.11 RLN36624.1 - 5.1 4.9 8.5 2.1 6.2 2.0 2.1 2 0 0 2 2 2 0 Prominin zf-BED PF02892.15 RLN36625.1 - 3.5e-05 23.7 0.0 6.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 BED zinc finger DUF659 PF04937.15 RLN36625.1 - 0.012 15.5 0.0 0.027 14.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF 659) MIP-T3_C PF17749.1 RLN36626.1 - 0.074 13.0 1.5 0.14 12.1 1.5 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region DUF848 PF05852.11 RLN36626.1 - 0.094 12.8 1.9 0.11 12.5 0.7 1.7 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) BssB_TutG PF18512.1 RLN36626.1 - 0.12 12.3 0.9 8.8 6.3 0.1 2.5 2 0 0 2 2 2 0 Benzylsuccinate synthase beta subunit Clat_adaptor_s PF01217.20 RLN36627.1 - 5.2e-28 97.8 0.3 8.3e-28 97.1 0.3 1.3 1 1 0 1 1 1 1 Clathrin adaptor complex small chain LMBR1 PF04791.16 RLN36628.1 - 0.0025 16.8 3.4 0.0033 16.4 3.4 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF1644 PF07800.12 RLN36628.1 - 0.023 14.8 8.1 0.063 13.3 8.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) Hid1 PF12722.7 RLN36628.1 - 0.16 10.1 7.0 0.21 9.7 7.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDHD PF02862.17 RLN36628.1 - 0.46 10.6 3.5 0.88 9.7 3.5 1.6 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 RLN36628.1 - 0.62 8.8 9.6 1.1 8.0 9.6 1.3 1 0 0 1 1 1 0 Presenilin DUF5624 PF18538.1 RLN36628.1 - 0.67 10.1 8.5 5.6 7.1 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5624) Ureide_permease PF07168.11 RLN36628.1 - 1.2 7.9 2.5 1 8.0 1.0 1.6 1 1 1 2 2 2 0 Ureide permease ALMT PF11744.8 RLN36628.1 - 4.6 6.0 12.0 7.9 5.2 12.0 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 RLN36628.1 - 6.6 4.5 13.2 8.5 4.1 13.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Histidinol_dh PF00815.20 RLN36628.1 - 8.4 5.3 12.0 14 4.5 12.0 1.3 1 0 0 1 1 1 0 Histidinol dehydrogenase DUF4407 PF14362.6 RLN36628.1 - 9.8 5.4 23.5 1.6 8.0 16.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DFP PF04127.15 RLN36629.1 - 4.1e-17 62.6 0.3 2.3e-12 47.2 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein BolA PF01722.18 RLN36630.1 - 2.7e-32 110.9 0.7 3.4e-32 110.6 0.7 1.1 1 0 0 1 1 1 1 BolA-like protein Ank_2 PF12796.7 RLN36680.1 - 3.7e-179 581.8 37.6 2.9e-23 82.2 0.2 10.3 1 1 10 11 11 11 11 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN36680.1 - 5.3e-127 398.1 17.1 4.5e-06 26.6 0.0 20.1 20 0 0 20 20 20 20 Ankyrin repeat Ank PF00023.30 RLN36680.1 - 9.8e-126 405.3 21.8 1.3e-06 28.6 0.0 20.1 20 0 0 20 20 20 20 Ankyrin repeat Ank_4 PF13637.6 RLN36680.1 - 2.3e-106 346.9 54.2 1.6e-09 38.1 0.1 15.5 4 3 13 18 18 18 18 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN36680.1 - 8.7e-106 344.6 41.5 7.4e-08 32.5 0.3 19.2 1 1 17 19 19 19 19 Ankyrin repeats (many copies) MEDS PF14417.6 RLN36680.1 - 2.7e-10 40.3 10.7 0.45 10.3 0.1 7.9 1 1 10 11 11 11 6 MEDS: MEthanogen/methylotroph, DcmR Sensory domain VWA_3_C PF18571.1 RLN36680.1 - 8.9e-10 38.3 20.9 17 5.4 0.0 15.2 18 0 0 18 18 18 0 von Willebrand factor type A C-terminal domain YlzJ PF14035.6 RLN36680.1 - 1.9e-08 34.4 0.0 2.5e+02 1.9 0.0 11.7 17 0 0 17 17 15 0 YlzJ-like protein Nepo_coat_C PF03688.14 RLN36680.1 - 2.5e-08 34.0 26.0 3.5 7.4 0.1 10.8 1 1 10 14 14 14 2 Nepovirus coat protein, C-terminal domain Imm_superinfect PF14373.6 RLN36680.1 - 4.7e-05 23.2 26.5 18 5.3 0.0 15.5 19 0 0 19 19 19 0 Superinfection immunity protein Urease_linker PF18473.1 RLN36680.1 - 0.00051 19.9 0.2 2e+02 1.9 0.0 7.8 11 0 0 11 11 11 0 Urease subunit beta-alpha linker domain IlvN PF07991.12 RLN36680.1 - 0.0054 16.3 6.0 61 3.1 0.0 6.8 5 4 3 8 8 8 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain SpoIIIAH PF12685.7 RLN36680.1 - 0.71 9.7 9.2 1.1e+02 2.5 0.0 6.8 9 0 0 9 9 9 0 SpoIIIAH-like protein SBP_bac_3 PF00497.20 RLN36680.1 - 1.6 8.1 8.3 25 4.2 0.1 5.7 3 2 0 5 5 5 0 Bacterial extracellular solute-binding proteins, family 3 tRNA_NucTran2_2 PF13735.6 RLN36680.1 - 1.7 8.7 15.7 11 5.9 0.1 7.1 5 4 5 10 10 10 0 tRNA nucleotidyltransferase domain 2 putative DUF3368 PF11848.8 RLN36680.1 - 2.6 7.9 4.8 4.1e+02 0.9 0.0 6.3 7 0 0 7 7 7 0 Domain of unknown function (DUF3368) UDPGT PF00201.18 RLN36682.1 - 5e-07 28.9 0.0 7.7e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 RLN36682.1 - 0.0036 17.3 0.0 0.0063 16.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Jiv90 PF14901.6 RLN36682.1 - 0.091 12.9 0.3 0.18 12.0 0.3 1.4 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone Mannosyl_trans3 PF11051.8 RLN36683.1 - 1.5e-29 103.2 0.0 1.5e-28 99.9 0.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.8 RLN36684.1 - 7.6e-34 117.3 0.0 2.4e-32 112.4 0.0 2.3 1 1 0 1 1 1 1 Mannosyltransferase putative MAJIN PF15077.6 RLN36684.1 - 6.7 6.4 12.9 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Membrane-anchored junction protein ADK PF00406.22 RLN36687.1 - 8.4e-36 123.3 0.0 1.3e-35 122.7 0.0 1.3 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 RLN36687.1 - 7.7e-26 91.1 0.0 1.1e-25 90.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RLN36687.1 - 1.5e-05 25.6 0.0 3.5e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RLN36687.1 - 8.1e-05 22.8 0.0 0.00021 21.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 RLN36687.1 - 0.0027 17.7 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 RLN36687.1 - 0.0033 16.7 0.1 0.3 10.3 0.1 2.6 2 1 0 2 2 2 1 Zeta toxin Thymidylate_kin PF02223.17 RLN36687.1 - 0.016 14.9 0.1 0.54 9.9 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase S1 PF00575.23 RLN36687.1 - 0.037 14.4 0.0 0.077 13.4 0.0 1.4 1 0 0 1 1 1 0 S1 RNA binding domain AAA_19 PF13245.6 RLN36687.1 - 0.057 13.7 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RLN36687.1 - 0.11 12.8 0.5 0.55 10.5 0.3 2.2 1 1 1 2 2 2 0 AAA domain COG4 PF08318.12 RLN36688.1 - 9.3e-14 51.2 0.2 1.5e-12 47.3 0.2 2.7 1 1 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.13 RLN36688.1 - 0.00017 20.6 1.2 0.00032 19.7 1.2 1.4 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Symplekin_C PF12295.8 RLN36688.1 - 0.35 11.0 2.9 0.4 10.8 0.7 2.2 3 0 0 3 3 3 0 Symplekin tight junction protein C terminal V-ATPase_H_N PF03224.14 RLN36689.1 - 2.8e-40 138.5 0.5 2.2e-38 132.3 0.1 2.1 2 0 0 2 2 2 2 V-ATPase subunit H V-ATPase_H_C PF11698.8 RLN36689.1 - 3e-40 137.0 1.7 5.3e-38 129.7 0.5 2.5 2 0 0 2 2 2 2 V-ATPase subunit H Arm PF00514.23 RLN36689.1 - 5e-09 35.9 3.7 0.52 10.4 0.0 4.9 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN36689.1 - 0.0034 17.5 0.9 1.4 9.3 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat DRIM PF07539.12 RLN36689.1 - 0.0061 14.9 0.2 0.018 13.4 0.0 1.8 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT_EZ PF13513.6 RLN36689.1 - 0.018 15.5 1.6 11 6.7 0.0 3.9 3 0 0 3 3 3 0 HEAT-like repeat Arm_2 PF04826.13 RLN36689.1 - 0.022 14.2 0.2 0.05 13.0 0.0 1.6 2 0 0 2 2 2 0 Armadillo-like Sod_Ni PF09055.11 RLN36689.1 - 0.029 14.9 0.6 0.095 13.3 0.0 2.3 3 0 0 3 3 3 0 Nickel-containing superoxide dismutase HEAT_2 PF13646.6 RLN36689.1 - 0.041 14.3 0.2 1.3 9.5 0.0 3.2 2 2 1 3 3 3 0 HEAT repeats DUF3295 PF11702.8 RLN36690.1 - 0.18 11.1 39.2 0.25 10.7 39.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) SOBP PF15279.6 RLN36690.1 - 1.1 9.8 25.0 1.5 9.4 25.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Hamartin PF04388.12 RLN36690.1 - 4 6.0 28.4 5.1 5.6 28.4 1.0 1 0 0 1 1 1 0 Hamartin protein DUF4551 PF15087.6 RLN36690.1 - 5.1 5.8 18.8 6.4 5.5 18.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Endomucin PF07010.12 RLN36690.1 - 5.4 6.9 31.3 8.3 6.3 31.3 1.3 1 0 0 1 1 1 0 Endomucin Myosin_head PF00063.21 RLN36691.1 - 1.5e-177 591.9 0.0 5e-123 411.7 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) AAA_22 PF13401.6 RLN36691.1 - 0.032 14.5 0.2 0.28 11.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain ATG16 PF08614.11 RLN36691.1 - 0.036 14.3 11.3 0.14 12.4 11.3 2.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) T2SSE PF00437.20 RLN36691.1 - 0.044 12.9 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Leu_zip PF15294.6 RLN36691.1 - 0.055 13.0 4.8 0.1 12.1 4.8 1.3 1 0 0 1 1 1 0 Leucine zipper Fib_alpha PF08702.10 RLN36691.1 - 0.17 12.1 1.8 0.44 10.7 1.8 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 RLN36691.1 - 0.33 11.0 3.1 0.72 9.9 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 RLN36691.1 - 0.87 9.7 7.7 1.7 8.7 7.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA_13 PF13166.6 RLN36691.1 - 1 7.9 7.0 1.9 7.0 5.2 2.0 2 0 0 2 2 2 0 AAA domain ADIP PF11559.8 RLN36691.1 - 2.3 8.3 10.3 5.2 7.1 10.3 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Pyridoxal_deC PF00282.19 RLN36692.1 - 6.9e-16 57.9 0.0 1.2e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 RLN36692.1 - 1.1e-05 24.6 0.1 5.2e-05 22.4 0.1 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 RLN36692.1 - 0.003 16.8 0.0 0.013 14.7 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II Adeno_E3B PF03376.14 RLN36693.1 - 4.5 7.6 10.3 0.15 12.3 3.8 1.9 2 1 0 2 2 2 0 Adenovirus E3B protein Phage_int_SAM_1 PF02899.17 RLN36694.1 - 0.011 16.0 0.1 0.054 13.8 0.0 2.1 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Phage_integrase PF00589.22 RLN36694.1 - 0.033 14.0 0.1 0.22 11.3 0.0 2.1 1 1 1 2 2 2 0 Phage integrase family Phage_int_SAM_4 PF13495.6 RLN36694.1 - 0.042 14.3 0.0 0.17 12.4 0.0 2.0 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain PHD PF00628.29 RLN36695.1 - 0.012 15.5 1.8 0.024 14.5 1.8 1.5 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 RLN36695.1 - 0.14 12.4 1.1 0.34 11.2 1.1 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 RLN36695.1 - 0.14 12.3 0.4 0.31 11.2 0.4 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_2 PF13639.6 RLN36697.1 - 2.6e-11 43.7 10.0 2.6e-11 43.7 10.0 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 RLN36697.1 - 3.1e-07 30.0 3.0 7.8e-07 28.7 3.0 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 RLN36697.1 - 4.2e-07 29.7 8.3 1.2e-06 28.2 8.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN36697.1 - 9e-07 28.6 9.6 2.6e-06 27.2 9.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN36697.1 - 1.9e-06 27.8 5.0 1.9e-06 27.8 5.0 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RLN36697.1 - 2e-06 27.5 5.8 4.7e-06 26.4 5.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN36697.1 - 2.2e-06 27.8 9.5 4e-06 27.0 8.4 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RLN36697.1 - 6.1e-06 26.1 6.9 1.7e-05 24.7 6.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RLN36697.1 - 0.0002 21.1 10.6 0.0067 16.3 3.4 2.5 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 RLN36697.1 - 0.0004 20.0 7.3 0.001 18.7 7.3 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 RLN36697.1 - 0.0035 17.4 4.3 0.0099 15.9 4.3 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 RLN36697.1 - 0.25 11.2 5.7 0.61 9.9 5.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Vps39_2 PF10367.9 RLN36697.1 - 0.59 10.6 5.1 0.36 11.3 1.5 2.2 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 RINGv PF12906.7 RLN36697.1 - 0.79 9.9 8.1 2.3 8.4 8.1 1.8 1 0 0 1 1 1 0 RING-variant domain Rad50_zn_hook PF04423.14 RLN36697.1 - 0.83 9.5 5.1 4 7.4 1.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-MYND PF01753.18 RLN36698.1 - 0.0029 17.7 3.1 0.0094 16.0 3.1 1.9 1 1 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 RLN36698.1 - 0.19 11.9 5.1 0.55 10.4 3.0 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 C1_1 PF00130.22 RLN36698.1 - 0.54 10.2 6.9 0.15 11.9 2.2 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_L37e PF01907.19 RLN36698.1 - 2.5 8.3 8.1 0.19 11.9 2.4 2.0 2 0 0 2 2 2 0 Ribosomal protein L37e zf-ribbon_3 PF13248.6 RLN36698.1 - 2.9 7.4 6.6 0.39 10.2 1.3 2.3 3 0 0 3 3 3 0 zinc-ribbon domain Prok-RING_1 PF14446.6 RLN36698.1 - 5.1 7.1 8.8 0.96 9.4 4.9 1.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 DUF2256 PF10013.9 RLN36698.1 - 7.8 6.7 10.4 8.1 6.7 0.4 3.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) FYVE PF01363.21 RLN36699.1 - 3.9e-10 39.7 11.7 8.6e-10 38.6 11.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger GAF_2 PF13185.6 RLN36699.1 - 3.2e-08 34.0 0.0 6e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 GAF domain Prok-RING_4 PF14447.6 RLN36699.1 - 0.025 14.4 3.6 0.072 13.0 3.6 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 SR-25 PF10500.9 RLN36699.1 - 0.05 13.2 13.0 0.075 12.6 13.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-RING_5 PF14634.6 RLN36699.1 - 0.55 10.2 12.8 1.3 9.0 12.8 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 RLN36699.1 - 3.2 8.2 11.1 8.3 6.8 11.1 1.8 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 RLN36699.1 - 5 7.2 8.0 12 6.0 8.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger FYVE PF01363.21 RLN36700.1 - 6.8e-10 38.9 13.7 1.5e-09 37.9 13.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF_2 PF13185.6 RLN36700.1 - 0.057 13.7 0.0 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 GAF domain zf-RING_5 PF14634.6 RLN36700.1 - 0.61 10.1 14.7 1.2 9.1 14.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-B_box PF00643.24 RLN36700.1 - 2.8 8.2 8.9 12 6.1 8.9 2.1 1 1 0 1 1 1 0 B-box zinc finger DUF3458_C PF17432.2 RLN36701.1 - 2.2e-29 102.9 0.3 3.4e-28 98.9 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 RLN36701.1 - 2.5e-27 95.9 0.3 4.7e-27 95.0 0.3 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 RLN36701.1 - 2.1e-12 47.6 0.1 4.7e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF3458 PF11940.8 RLN36701.1 - 6e-09 36.2 0.9 1.6e-08 34.9 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3458) Ig-like fold Ribophorin_I PF04597.14 RLN36701.1 - 0.022 14.0 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribophorin I VPS13_C PF16909.5 RLN36702.1 - 1.1e-16 61.2 0.0 2.2e-16 60.1 0.0 1.5 1 1 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal DUF812 PF05667.11 RLN36767.1 - 4.3e-90 303.3 15.8 2.1e-88 297.7 15.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF812) PSII_Pbs31 PF18240.1 RLN36767.1 - 0.12 12.8 2.8 0.52 10.8 2.8 2.1 1 0 0 1 1 1 0 Photosystem II Psb31 protein MDD_C PF18376.1 RLN36767.1 - 0.34 10.6 2.9 1.7 8.3 0.0 2.8 3 1 0 3 3 3 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain Seryl_tRNA_N PF02403.22 RLN36767.1 - 3.7 7.8 25.4 0.22 11.8 11.1 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain KxDL PF10241.9 RLN36767.1 - 7 7.0 20.3 5.4 7.4 0.2 4.1 3 1 1 4 4 4 0 Uncharacterized conserved protein CRAL_TRIO PF00650.20 RLN36770.1 - 8.3e-29 100.4 0.0 1.5e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain ribosomal_L24 PF17136.4 RLN36770.1 - 5.5e-16 58.7 0.1 1.5e-15 57.3 0.1 1.8 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 RLN36770.1 - 2e-06 27.5 2.8 2e-06 27.5 2.8 1.9 2 0 0 2 2 2 1 KOW motif PELOTA_1 PF15608.6 RLN36770.1 - 0.096 12.6 0.1 0.43 10.5 0.0 2.1 2 0 0 2 2 2 0 PELOTA RNA binding domain RNA_pol_3_Rpc31 PF11705.8 RLN36771.1 - 0.21 11.8 11.1 24 5.1 11.1 2.3 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 RLN36771.1 - 6.9 4.6 8.2 10 4.1 8.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi AT_hook PF02178.19 RLN36772.1 - 6.2 7.1 32.0 0.16 11.9 5.5 4.4 3 2 1 4 4 4 0 AT hook motif Tim17 PF02466.19 RLN36775.1 - 0.0067 16.8 3.2 0.013 15.9 3.2 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_YMGG PF13441.6 RLN36775.1 - 0.0078 15.9 15.2 0.019 14.7 15.3 1.6 1 1 0 1 1 1 1 YMGG-like Gly-zipper MFS_1 PF07690.16 RLN36775.1 - 0.043 12.7 0.0 0.053 12.4 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily TPD PF14811.6 RLN36775.1 - 0.081 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif Rick_17kDa_Anti PF05433.15 RLN36775.1 - 0.11 12.4 12.2 1.6 8.6 4.2 2.2 2 0 0 2 2 2 0 Glycine zipper 2TM domain Bacteriocin_IIc PF10439.9 RLN36775.1 - 0.36 11.0 14.2 2 8.6 14.2 2.1 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.6 RLN36775.1 - 2 8.5 19.8 4.2 7.4 4.6 2.0 1 1 1 2 2 2 0 Glycine zipper Gly-zipper_OmpA PF13436.6 RLN36775.1 - 5.3 6.9 21.0 5.4 6.9 4.9 2.2 2 0 0 2 2 2 0 Glycine-zipper domain PKD_channel PF08016.12 RLN36776.1 - 6.3e-06 25.1 0.9 0.022 13.5 0.0 2.5 2 1 1 3 3 3 2 Polycystin cation channel TFIIIC_delta PF12657.7 RLN36777.1 - 1.5e-14 54.4 0.3 2.1e-12 47.4 0.0 2.4 2 0 0 2 2 2 2 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 RLN36777.1 - 1.5e-08 34.5 0.5 3.3e-08 33.4 0.5 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex WD40 PF00400.32 RLN36777.1 - 0.0006 20.6 10.2 0.003 18.3 0.2 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.8 RLN36777.1 - 0.024 13.3 0.1 0.038 12.6 0.1 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Octopine_DH PF02317.17 RLN36778.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain RACo_linker PF17650.1 RLN36778.1 - 0.24 11.3 1.3 0.54 10.1 1.3 1.5 1 0 0 1 1 1 0 RACo linker region DFRP_C PF16543.5 RLN36778.1 - 0.49 10.9 0.1 0.49 10.9 0.1 2.3 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 Thg1C PF14413.6 RLN36778.1 - 0.73 10.0 2.9 7.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Thg1 C terminal domain Glyco_hydro_17 PF00332.18 RLN36827.1 - 0.0012 18.5 1.4 0.082 12.5 0.2 2.4 2 1 0 2 2 2 2 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.13 RLN36827.1 - 0.0016 17.5 0.1 0.0032 16.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 DUF1067 PF06362.11 RLN36827.1 - 0.03 15.1 0.2 0.066 14.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1067) DUF823 PF05689.11 RLN36827.1 - 0.057 13.2 1.3 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF823) Myb_DNA-bind_4 PF13837.6 RLN36828.1 - 3.5e-05 24.1 0.0 0.075 13.4 0.0 2.7 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 RLN36828.1 - 0.00011 22.2 0.3 1.1 9.4 0.1 3.5 2 1 0 2 2 2 2 Myb/SANT-like DNA-binding domain DUF2491 PF10679.9 RLN36828.1 - 0.033 13.3 0.7 0.079 12.1 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) APG5 PF04106.12 RLN36829.1 - 3.8e-51 173.9 0.0 4.4e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg5 U-box PF04564.15 RLN36830.1 - 3.8e-20 71.8 0.1 8.8e-20 70.7 0.1 1.6 1 0 0 1 1 1 1 U-box domain TPR_2 PF07719.17 RLN36830.1 - 9e-05 22.3 1.5 0.32 11.2 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat zf-NOSIP PF15906.5 RLN36830.1 - 0.00061 19.9 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein TPR_1 PF00515.28 RLN36830.1 - 0.0078 16.0 2.0 1.3 9.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN36830.1 - 0.011 16.0 5.7 0.057 13.7 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat zf-Nse PF11789.8 RLN36830.1 - 0.041 13.7 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TPR_16 PF13432.6 RLN36830.1 - 1.5 9.5 0.0 1.5 9.5 0.0 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Ank_2 PF12796.7 RLN36831.1 - 4e-36 123.4 7.1 5.4e-07 30.1 0.1 6.9 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN36831.1 - 1e-35 121.6 26.4 0.00013 22.4 0.1 12.5 6 3 6 12 12 12 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN36831.1 - 7.9e-29 99.4 21.4 0.013 15.8 0.1 15.6 4 1 13 17 17 17 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN36831.1 - 1.9e-20 70.8 4.6 11 7.0 0.0 15.4 12 2 5 17 17 17 3 Ankyrin repeat DUF5049 PF16468.5 RLN36831.1 - 0.00012 21.9 0.0 30 4.6 0.0 6.2 6 2 2 8 8 8 0 Domain of unknown function (DUF5049) Ank PF00023.30 RLN36831.1 - 0.0026 18.1 4.8 1.8e+02 2.9 0.0 8.8 6 3 2 8 8 8 0 Ankyrin repeat Peptidase_M20 PF01546.28 RLN36831.1 - 0.14 11.8 0.3 0.38 10.4 0.0 1.9 2 0 0 2 2 2 0 Peptidase family M20/M25/M40 Rad17 PF03215.15 RLN36831.1 - 0.17 11.8 0.0 0.44 10.4 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain Aldo_ket_red PF00248.21 RLN36835.1 - 1.2e-24 87.0 0.0 1.2e-23 83.8 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 RLN36836.1 - 2.9e-29 102.2 0.0 3.5e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 RLN36837.1 - 1.5e-133 444.6 0.0 1.3e-70 237.9 0.0 2.6 2 1 0 2 2 2 2 Aldo/keto reductase family DUF948 PF06103.11 RLN36837.1 - 0.00045 20.4 0.0 2.1 8.7 0.0 2.7 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF948) NRD1_2 PF01995.16 RLN36837.1 - 0.043 13.1 0.0 8.6 5.5 0.0 2.2 2 0 0 2 2 2 0 NrpR regulatory domains NRD1 and 2 HTH_Mga PF08280.11 RLN36837.1 - 0.11 12.5 0.2 29 4.8 0.0 2.7 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain DUF2334 PF10096.9 RLN36837.1 - 0.14 11.7 0.0 0.54 9.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) Sugar-bind PF04198.13 RLN36837.1 - 0.21 10.7 0.1 20 4.2 0.0 2.1 2 0 0 2 2 2 0 Putative sugar-binding domain DUF4145 PF13643.6 RLN36837.1 - 0.21 11.7 0.2 41 4.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) FlgN PF05130.12 RLN36837.1 - 0.28 11.7 1.4 27 5.3 0.1 2.2 2 0 0 2 2 2 0 FlgN protein RCC1 PF00415.18 RLN36840.1 - 6.3e-34 116.4 9.5 6.6e-12 45.9 0.3 6.3 6 1 0 6 6 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN36840.1 - 1.5e-26 91.5 5.0 1.7e-09 37.2 0.1 5.3 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat zf-RING_2 PF13639.6 RLN36840.1 - 5.6e-09 36.2 11.1 5.6e-09 36.2 11.1 1.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 RLN36840.1 - 6.6e-07 29.5 8.5 1.4e-06 28.5 8.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 RLN36840.1 - 7.6e-06 25.6 10.3 1.1e-05 25.0 8.1 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 RLN36840.1 - 3.5e-05 23.8 4.0 8.1e-05 22.6 4.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 RLN36840.1 - 4.1e-05 23.4 10.6 7.4e-05 22.5 10.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN36840.1 - 0.0011 18.9 7.6 0.0024 17.8 7.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RLN36840.1 - 0.0027 17.5 11.3 0.0063 16.3 11.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN36840.1 - 0.07 13.0 8.1 0.14 12.0 8.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN36840.1 - 0.099 12.6 10.7 0.2 11.6 10.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 RLN36840.1 - 0.14 11.8 6.9 0.31 10.7 6.9 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 RLN36840.1 - 0.3 11.0 9.0 0.57 10.1 9.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 RLN36840.1 - 0.56 10.4 6.7 1.4 9.2 6.7 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.6 RLN36840.1 - 1.3 9.3 7.3 8.3 6.6 7.0 2.4 2 1 0 2 2 2 0 PHD-zinc-finger like domain Y_phosphatase2 PF03162.13 RLN36841.1 - 9.1e-41 139.2 0.0 1.2e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 RLN36841.1 - 0.0016 18.5 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 RLN36841.1 - 0.004 16.8 0.0 0.0058 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 RLN36841.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain IMS PF00817.20 RLN36842.1 - 1e-42 145.6 0.4 2.7e-42 144.3 0.1 1.9 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 RLN36842.1 - 3.9e-18 66.2 2.0 1e-17 64.9 1.3 2.1 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain zf-ribbon_3 PF13248.6 RLN36842.1 - 0.0054 16.1 0.8 1.3 8.6 0.0 2.5 2 0 0 2 2 2 2 zinc-ribbon domain Lar_restr_allev PF14354.6 RLN36842.1 - 0.0055 17.1 2.1 1.7 9.0 0.2 2.8 2 0 0 2 2 2 2 Restriction alleviation protein Lar IMS_HHH PF11798.8 RLN36842.1 - 0.0078 16.5 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif zf-C2H2 PF00096.26 RLN36842.1 - 0.1 13.1 0.8 30 5.3 0.0 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Prok-RING_4 PF14447.6 RLN36842.1 - 0.16 11.8 0.5 23 4.9 0.1 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C2H2_4 PF13894.6 RLN36842.1 - 0.17 12.8 2.8 20 6.4 0.0 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger ABC_tran PF00005.27 RLN36843.1 - 2.8e-46 157.5 0.0 2.1e-22 80.1 0.0 3.7 3 2 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 RLN36843.1 - 8.6e-15 55.3 0.3 0.00037 20.4 0.0 4.0 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RLN36843.1 - 1.6e-12 47.4 0.1 0.0081 15.6 0.0 4.2 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RLN36843.1 - 4.8e-08 33.8 8.3 0.0029 18.1 0.0 4.1 4 1 0 4 4 4 2 AAA domain RNA_helicase PF00910.22 RLN36843.1 - 9.9e-07 29.1 0.1 0.1 13.0 0.0 4.3 4 0 0 4 4 4 2 RNA helicase AAA_22 PF13401.6 RLN36843.1 - 1.4e-06 28.6 0.3 0.099 12.9 0.0 4.4 5 1 0 5 5 3 2 AAA domain AAA_29 PF13555.6 RLN36843.1 - 1.8e-06 27.6 0.0 0.061 13.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 RLN36843.1 - 6.9e-06 26.4 0.0 0.26 11.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA PF00004.29 RLN36843.1 - 7.8e-06 26.3 0.0 0.017 15.6 0.0 3.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 RLN36843.1 - 9.9e-06 25.6 0.0 0.036 14.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RLN36843.1 - 1.3e-05 25.2 0.1 0.14 12.2 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase Chromo PF00385.24 RLN36843.1 - 2.3e-05 24.2 2.9 2.3e-05 24.2 2.9 2.2 2 0 0 2 2 1 1 Chromo (CHRromatin Organisation MOdifier) domain NACHT PF05729.12 RLN36843.1 - 5.1e-05 23.3 0.1 0.0066 16.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Vac14_Fab1_bd PF12755.7 RLN36843.1 - 5.6e-05 23.7 0.2 0.37 11.4 0.0 3.0 3 0 0 3 3 2 2 Vacuolar 14 Fab1-binding region AAA_16 PF13191.6 RLN36843.1 - 9.6e-05 22.8 0.3 0.76 10.1 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.6 RLN36843.1 - 0.00017 22.1 6.7 0.55 10.8 0.0 4.3 5 0 0 5 5 3 2 AAA domain AAA_33 PF13671.6 RLN36843.1 - 0.00018 21.7 0.1 1.4 9.0 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 RLN36843.1 - 0.00023 21.0 6.9 0.12 12.0 0.0 4.4 5 0 0 5 5 5 2 AAA ATPase domain Rad17 PF03215.15 RLN36843.1 - 0.0003 20.7 0.0 0.44 10.4 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_27 PF13514.6 RLN36843.1 - 0.00066 19.3 1.3 0.26 10.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain G-alpha PF00503.20 RLN36843.1 - 0.0011 18.2 0.0 2.3 7.3 0.0 3.2 3 0 0 3 3 3 1 G-protein alpha subunit AAA_24 PF13479.6 RLN36843.1 - 0.0017 18.1 0.2 0.72 9.5 0.0 3.6 4 0 0 4 4 2 1 AAA domain MeaB PF03308.16 RLN36843.1 - 0.0022 17.1 0.2 1.9 7.4 0.1 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB SbcCD_C PF13558.6 RLN36843.1 - 0.0026 18.0 0.1 0.73 10.1 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit CLASP_N PF12348.8 RLN36843.1 - 0.0026 17.3 0.1 0.019 14.5 0.0 2.2 1 1 0 2 2 2 1 CLASP N terminal DUF87 PF01935.17 RLN36843.1 - 0.0045 17.1 1.2 1.1 9.3 0.0 4.0 4 0 0 4 4 4 1 Helicase HerA, central domain AAA_30 PF13604.6 RLN36843.1 - 0.0047 16.7 0.1 3.4 7.4 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_7 PF12775.7 RLN36843.1 - 0.0048 16.4 0.0 2.8 7.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 RLN36843.1 - 0.0073 16.3 0.0 1.1 9.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain HEAT_2 PF13646.6 RLN36843.1 - 0.013 15.9 1.5 3.2 8.2 0.0 3.7 3 1 0 3 3 3 0 HEAT repeats Cnd1 PF12717.7 RLN36843.1 - 0.017 15.2 2.5 3.6 7.6 0.1 3.0 1 1 2 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Cytidylate_kin PF02224.18 RLN36843.1 - 0.017 14.9 0.5 4.9 6.8 0.0 3.2 3 0 0 3 3 3 0 Cytidylate kinase Dynamin_N PF00350.23 RLN36843.1 - 0.021 14.9 1.0 1.1 9.3 0.0 3.5 3 0 0 3 3 3 0 Dynamin family Mg_chelatase PF01078.21 RLN36843.1 - 0.025 13.9 0.3 13 5.1 0.0 3.3 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 RLN36843.1 - 0.037 13.6 0.0 8.9 5.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 RLN36843.1 - 0.038 13.9 1.0 29 4.5 0.1 3.9 4 0 0 4 4 4 0 NTPase Kdo_hydroxy PF11004.8 RLN36843.1 - 0.041 13.1 0.0 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase Viral_helicase1 PF01443.18 RLN36843.1 - 0.042 13.6 0.0 13 5.5 0.0 3.4 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 RLN36843.1 - 0.044 12.9 0.0 9.3 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PRK PF00485.18 RLN36843.1 - 0.074 12.8 0.0 5.9 6.6 0.0 2.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATPase_2 PF01637.18 RLN36843.1 - 0.085 12.8 0.0 0.085 12.8 0.0 4.4 5 0 0 5 5 4 0 ATPase domain predominantly from Archaea ATP-synt_ab PF00006.25 RLN36843.1 - 0.096 12.3 0.0 3.1 7.4 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain HEAT PF02985.22 RLN36843.1 - 0.11 12.9 1.9 23 5.6 0.0 4.0 3 1 1 4 4 3 0 HEAT repeat TsaE PF02367.17 RLN36843.1 - 0.12 12.4 0.0 28 4.7 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 RLN36843.1 - 0.12 12.4 1.0 14 5.7 0.0 3.8 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) HEAT_EZ PF13513.6 RLN36843.1 - 0.46 11.0 2.1 50 4.6 0.0 4.4 3 2 2 5 5 4 0 HEAT-like repeat ATP_bind_1 PF03029.17 RLN36843.1 - 1.5 8.5 4.0 13 5.5 0.2 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein PTPA PF03095.15 RLN36844.1 - 9e-89 297.9 0.0 3.3e-88 296.0 0.0 1.7 1 1 1 2 2 2 1 Phosphotyrosyl phosphate activator (PTPA) protein Strumpellin PF10266.9 RLN36845.1 - 0 1424.6 0.2 0 1424.3 0.2 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin PhoU_div PF01865.16 RLN36845.1 - 0.49 9.7 4.6 0.3 10.4 1.2 2.4 2 1 0 2 2 2 0 Protein of unknown function DUF47 DUF4375 PF14300.6 RLN36845.1 - 3.4 8.0 5.1 29 5.0 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Pkinase_Tyr PF07714.17 RLN36846.1 - 3.6e-37 128.0 0.0 6.6e-33 114.1 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN36846.1 - 2.8e-35 122.0 0.0 1.9e-32 112.7 0.0 2.7 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 RLN36846.1 - 0.7 9.8 5.5 1.9 8.3 0.0 3.7 3 1 1 4 4 4 0 Phosphotransferase enzyme family Aldo_ket_red PF00248.21 RLN36847.1 - 1.6e-47 162.1 0.0 5.3e-28 98.1 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family Aldo_ket_red PF00248.21 RLN36848.1 - 5.1e-64 216.3 0.0 6.9e-63 212.6 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Mitofilin PF09731.9 RLN36864.1 - 2.8 6.7 11.6 3.2 6.5 11.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PBP1_TM PF14812.6 RLN36867.1 - 5.8 7.4 14.6 2.7 8.4 7.0 2.9 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Methyltransf_24 PF13578.6 RLN36868.1 - 0.00012 23.1 0.0 0.0081 17.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain DUF4457 PF14652.6 RLN36869.1 - 2.9e-159 529.6 0.0 2.7e-106 355.5 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 RLN36869.1 - 0.0065 16.5 0.0 16 5.5 0.0 4.2 4 0 0 4 4 4 1 Sad1 / UNC-like C-terminal CBM_1 PF00734.18 RLN36870.1 - 3.8e-05 23.5 3.3 3.8e-05 23.5 3.3 7.7 7 2 0 7 7 7 4 Fungal cellulose binding domain GlgS PF08971.11 RLN36871.1 - 0.16 12.0 4.0 5.6 7.1 0.1 3.1 3 1 1 4 4 4 0 Glycogen synthesis protein GTP_EFTU PF00009.27 RLN36873.1 - 1.8e-58 197.3 0.0 3.4e-58 196.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 RLN36873.1 - 3.4e-14 52.7 0.0 9.8e-14 51.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 RLN36873.1 - 5.9e-13 48.7 0.0 1.4e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 RLN36873.1 - 4.2e-07 30.3 0.2 1.9e-06 28.1 0.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 RLN36873.1 - 6.4e-06 25.9 0.1 3e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 RLN36873.1 - 0.046 13.8 0.0 0.16 12.0 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase Zip PF02535.22 RLN36874.1 - 8.8e-25 87.6 13.0 5.4e-24 85.0 13.0 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter SpoIIIAC PF06686.11 RLN36874.1 - 0.74 10.0 5.3 0.15 12.3 0.8 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family Zip PF02535.22 RLN36875.1 - 9e-19 67.9 18.3 5.9e-18 65.2 18.3 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter CBM_1 PF00734.18 RLN36877.1 - 1.1e-08 34.9 20.0 3.4e-05 23.7 6.0 3.3 4 0 0 4 4 4 2 Fungal cellulose binding domain DUF3446 PF11928.8 RLN36877.1 - 0.012 16.0 4.9 0.013 15.8 2.0 2.1 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF3580 PF12117.8 RLN36877.1 - 0.044 14.0 13.9 0.1 12.8 1.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3580) NinB PF05772.12 RLN36877.1 - 0.066 13.0 0.1 8.6 6.2 0.0 2.1 2 0 0 2 2 2 0 NinB protein CLIP_SPH_Scar PF18399.1 RLN36877.1 - 0.19 11.9 15.3 0.53 10.4 1.6 2.5 2 1 0 2 2 2 0 Clip-domain serine protease homolog Scarface DUF2650 PF10853.8 RLN36877.1 - 0.8 9.5 7.8 7.1 6.4 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) Zip PF02535.22 RLN36879.1 - 8.4e-16 58.1 13.0 2.3e-15 56.7 13.0 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter LCM PF04072.14 RLN36880.1 - 1.2e-39 136.2 0.1 1.2e-39 136.2 0.1 1.8 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase DUF659 PF04937.15 RLN36880.1 - 6.7e-13 48.8 0.0 2.6e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 RLN36880.1 - 0.00018 21.2 0.6 0.00039 20.2 0.6 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 RLN36880.1 - 0.035 14.1 0.3 0.072 13.1 0.3 1.5 1 0 0 1 1 1 0 BED zinc finger TFIIA PF03153.13 RLN36880.1 - 0.062 13.3 16.9 0.099 12.6 16.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 RLN36880.1 - 1.1 7.9 23.8 1.7 7.3 23.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.9 RLN36880.1 - 1.4 9.2 17.3 2.5 8.3 17.3 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Spt20 PF12090.8 RLN36880.1 - 3.1 7.3 9.6 5.9 6.4 9.6 1.4 1 0 0 1 1 1 0 Spt20 family SRP-alpha_N PF04086.13 RLN36880.1 - 4.2 7.2 9.6 7.4 6.4 9.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal fn3 PF00041.21 RLN36881.1 - 3.5e-11 43.3 1.0 2.1e-07 31.2 0.1 2.6 2 0 0 2 2 2 2 Fibronectin type III domain SAM_2 PF07647.17 RLN36881.1 - 4.4e-06 26.7 0.0 8.6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EF-hand_1 PF00036.32 RLN36881.1 - 1.3e-05 24.4 1.7 0.23 11.1 0.0 3.4 2 1 1 3 3 3 3 EF hand SAM_1 PF00536.30 RLN36881.1 - 8.2e-05 23.0 0.0 0.00015 22.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EF-hand_5 PF13202.6 RLN36881.1 - 8.6e-05 21.9 0.7 3.4 7.3 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 RLN36881.1 - 0.00029 21.2 4.9 0.0016 18.9 4.9 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN36881.1 - 0.00055 19.7 2.8 5.4 7.2 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 RLN36881.1 - 0.0032 17.3 1.1 0.052 13.4 0.1 2.9 2 1 1 3 3 3 1 EF-hand domain pair BpuSI_N PF15516.6 RLN36881.1 - 0.042 13.8 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 BpuSI N-terminal domain fn3_4 PF16794.5 RLN36881.1 - 0.047 13.6 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 Fibronectin-III type domain GTP_EFTU PF00009.27 RLN36882.1 - 4.4e-21 75.3 0.1 6.8e-21 74.7 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 RLN36882.1 - 0.0019 18.6 0.2 0.0056 17.1 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RLN36882.1 - 0.0054 16.8 0.0 0.022 14.9 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase HyaE PF07449.11 RLN36882.1 - 0.1 12.6 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE MARVEL PF01284.23 RLN36896.1 - 8.3e-07 29.1 5.0 1e-06 28.9 5.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain Glug PF07581.12 RLN36896.1 - 0.044 14.2 0.2 0.095 13.2 0.2 1.6 1 0 0 1 1 1 0 The GLUG motif Ost5 PF05251.12 RLN36896.1 - 0.11 12.7 6.1 3.3 8.0 0.8 2.1 1 1 1 2 2 2 0 Oligosaccharyltransferase subunit 5 Tom6 PF17112.5 RLN36896.1 - 5.7 6.5 5.4 1.2 8.7 0.5 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom6, fungal p450 PF00067.22 RLN36899.1 - 1.8e-31 109.4 0.0 2.8e-31 108.8 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Choline_transpo PF04515.12 RLN36900.1 - 1.7e-44 152.3 12.3 1.7e-44 152.3 12.3 2.7 2 2 1 3 3 3 2 Plasma-membrane choline transporter Oxidored_q3 PF00499.20 RLN36900.1 - 1.8 8.3 15.3 5.6 6.7 15.3 1.8 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 VASt PF16016.5 RLN36901.1 - 4e-23 82.5 0.0 9e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain FYVE PF01363.21 RLN36901.1 - 1.2e-11 44.6 7.4 2.7e-11 43.4 7.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger GRAM PF02893.20 RLN36901.1 - 1.2e-07 31.6 0.3 5.5e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 GRAM domain IBR PF01485.21 RLN36901.1 - 1.5 9.1 6.5 0.66 10.2 3.4 2.1 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 RLN36901.1 - 2.1 8.6 7.3 5.3 7.3 7.3 1.7 1 0 0 1 1 1 0 AN1-like Zinc finger SfLAP PF11139.8 RLN36903.1 - 0.0082 15.6 0.2 0.0082 15.6 0.2 1.9 2 0 0 2 2 2 1 Sap, sulfolipid-1-addressing protein DUF202 PF02656.15 RLN36903.1 - 0.045 14.2 0.6 0.045 14.2 0.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Tim44 PF04280.15 RLN36905.1 - 0.00014 22.0 4.9 0.35 11.0 0.1 3.5 3 1 1 4 4 4 2 Tim44-like domain SH2 PF00017.24 RLN36918.1 - 3.2e-05 23.9 0.0 5.1e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 SH2 domain Cbl_N3 PF02762.14 RLN36918.1 - 0.096 12.6 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain COX5B PF01215.19 RLN36919.1 - 1.2e-11 44.5 0.0 2.7e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb MAP65_ASE1 PF03999.12 RLN36919.1 - 0.0018 17.1 7.1 0.0024 16.7 7.1 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF4407 PF14362.6 RLN36919.1 - 0.21 10.9 9.0 0.29 10.4 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RWP-RK PF02042.15 RLN36920.1 - 9.5e-20 70.3 0.2 1.6e-19 69.6 0.2 1.4 1 0 0 1 1 1 1 RWP-RK domain Myb_DNA-binding PF00249.31 RLN36920.1 - 1e-11 44.8 0.2 2.3e-11 43.7 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN36920.1 - 0.0092 16.2 1.4 0.011 15.9 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN36920.1 - 0.0098 15.8 0.2 0.033 14.1 0.0 2.0 2 0 0 2 2 2 1 Myb DNA-binding like FGE-sulfatase PF03781.16 RLN36921.1 - 1.6e-23 83.6 3.1 4.3e-23 82.2 3.1 1.7 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Pkinase_Tyr PF07714.17 RLN36924.1 - 3.5e-20 72.4 0.0 6.7e-12 45.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN36924.1 - 2.4e-14 53.3 0.0 1.3e-08 34.5 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain DUF4214 PF13946.6 RLN36924.1 - 0.013 15.5 0.7 0.055 13.5 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4214) Ank_2 PF12796.7 RLN36926.1 - 5.4e-31 107.0 10.5 2.5e-06 28.0 0.1 6.9 2 2 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN36926.1 - 1.2e-30 105.4 11.2 2.5e-05 24.7 0.1 9.5 6 4 1 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN36926.1 - 3.4e-25 87.8 16.1 0.0065 16.8 0.0 12.5 8 2 5 13 13 13 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN36926.1 - 1.4e-15 55.8 8.6 14 6.6 0.0 12.2 13 0 0 13 13 13 2 Ankyrin repeat Ank PF00023.30 RLN36926.1 - 0.00075 19.8 6.8 42 4.8 0.1 7.9 5 2 2 7 7 7 0 Ankyrin repeat DUF3322 PF11795.8 RLN36926.1 - 0.25 11.4 3.2 91 3.0 0.0 4.8 3 2 3 6 6 6 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Antimicrobial19 PF08225.11 RLN36926.1 - 6.4 6.5 6.0 4.4 7.0 1.6 2.7 2 0 0 2 2 2 0 Pseudin antimicrobial peptide VWA_2 PF13519.6 RLN36927.1 - 5.8e-05 23.7 0.3 0.00015 22.3 0.3 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 RLN36927.1 - 0.00011 22.6 0.2 0.0002 21.7 0.2 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain APC1_C PF18122.1 RLN36927.1 - 0.051 13.5 1.1 0.51 10.3 0.5 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain DUF2428 PF10350.9 RLN36937.1 - 5.7e-53 180.0 0.1 3.5e-52 177.4 0.0 2.5 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) Methyltransf_28 PF02636.17 RLN36937.1 - 0.049 13.3 0.2 0.11 12.1 0.2 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase TraG_N PF07916.11 RLN36938.1 - 0.17 10.7 4.1 0.28 10.0 4.1 1.3 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Phasin PF05597.11 RLN36938.1 - 2.3 8.2 27.9 0.81 9.7 9.1 3.9 4 1 0 5 5 5 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Prominin PF05478.11 RLN36938.1 - 2.9 5.7 14.2 0.77 7.6 11.0 1.7 2 0 0 2 2 2 0 Prominin betaPIX_CC PF16523.5 RLN36939.1 - 0.014 15.2 2.7 0.023 14.5 0.6 2.3 2 0 0 2 2 2 0 betaPIX coiled coil NEMO PF11577.8 RLN36939.1 - 0.037 14.0 4.0 0.13 12.3 4.0 2.0 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO FH2 PF02181.23 RLN36939.1 - 0.47 9.5 6.9 0.3 10.2 1.2 2.3 1 1 0 2 2 2 0 Formin Homology 2 Domain PDE4_UCR PF18100.1 RLN36939.1 - 0.62 10.7 6.6 0.12 13.1 1.0 2.4 2 0 0 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) DUF3450 PF11932.8 RLN36939.1 - 0.67 9.2 24.6 0.065 12.5 7.5 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF3450) LPP PF04728.13 RLN36939.1 - 0.97 9.9 9.4 1.8 9.0 2.1 4.0 3 0 0 3 3 3 0 Lipoprotein leucine-zipper PTPA PF03095.15 RLN36939.1 - 1.2 8.5 6.8 3.1 7.2 2.0 2.1 1 1 1 2 2 2 0 Phosphotyrosyl phosphate activator (PTPA) protein ZapB PF06005.12 RLN36939.1 - 4.5 7.8 22.8 29 5.2 3.0 4.8 3 2 1 4 4 4 0 Cell division protein ZapB DUF2205 PF10224.9 RLN36939.1 - 8.5 6.5 11.4 0.58 10.2 0.8 3.2 3 1 0 3 3 3 0 Short coiled-coil protein Peroxidase_2 PF01328.17 RLN36940.1 - 3.5e-52 177.7 0.0 4.2e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 EF-hand_6 PF13405.6 RLN36941.1 - 3.7e-30 101.3 9.3 2.6e-05 23.8 0.1 9.5 10 0 0 10 10 10 7 EF-hand domain EF-hand_7 PF13499.6 RLN36941.1 - 1.1e-29 102.7 1.3 4.6e-06 27.0 0.0 7.0 5 1 2 7 7 7 7 EF-hand domain pair EF-hand_1 PF00036.32 RLN36941.1 - 1.2e-29 99.6 4.5 5.2e-06 25.6 0.1 9.2 9 0 0 9 9 9 7 EF hand EF-hand_8 PF13833.6 RLN36941.1 - 7e-20 70.6 9.0 0.0012 18.6 0.1 8.5 8 1 1 9 9 9 4 EF-hand domain pair EF-hand_5 PF13202.6 RLN36941.1 - 6.1e-13 47.6 15.9 7.4e-05 22.1 0.1 8.0 9 0 0 9 9 9 3 EF hand SPARC_Ca_bdg PF10591.9 RLN36941.1 - 0.00065 20.0 7.3 2.5 8.5 0.0 6.7 7 2 0 7 7 7 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RLN36941.1 - 0.0013 18.7 0.3 0.035 14.1 0.0 2.9 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand Dzip-like_N PF13815.6 RLN36941.1 - 0.028 14.4 0.2 0.028 14.4 0.2 3.1 3 0 0 3 3 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal VCBS PF13517.6 RLN36941.1 - 0.065 13.8 0.3 4.8 7.9 0.0 3.2 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF5576 PF17739.1 RLN36941.1 - 0.65 10.1 2.3 22 5.2 0.5 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5576) IQ PF00612.27 RLN36941.1 - 1.1 9.3 8.4 1.6 8.8 0.1 3.1 3 0 0 3 3 3 0 IQ calmodulin-binding motif Peptidase_S41 PF03572.18 RLN36942.1 - 0.004 16.7 0.4 0.015 14.9 0.4 1.9 2 0 0 2 2 2 1 Peptidase family S41 DUF5063 PF16702.5 RLN36942.1 - 0.068 13.6 8.7 0.04 14.3 1.1 4.0 3 1 0 3 3 3 0 Domain of unknown function (DUF5063) KIP1 PF07765.12 RLN36942.1 - 3.9 7.7 10.3 8.5 6.6 2.2 5.4 3 1 1 4 4 4 0 KIP1-like protein DUF4203 PF13886.6 RLN36943.1 - 2.3e-47 161.3 24.0 3.2e-47 160.8 24.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Glyco_trans_4_2 PF13477.6 RLN36943.1 - 0.012 15.7 0.1 0.023 14.7 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like DUF308 PF03729.13 RLN36943.1 - 0.46 10.8 31.6 0.21 12.0 4.9 4.4 1 1 4 5 5 5 0 Short repeat of unknown function (DUF308) Holin_BlyA PF05102.12 RLN36943.1 - 0.67 10.0 3.3 19 5.3 0.0 2.8 3 0 0 3 3 3 0 holin, BlyA family Phage_holin_5_1 PF06946.11 RLN36943.1 - 8.9 6.8 10.6 2.4 8.6 2.9 2.6 1 1 1 2 2 2 0 Bacteriophage A118-like holin, Hol118 DUF4203 PF13886.6 RLN36944.1 - 4.7e-41 140.7 35.0 4.7e-41 140.7 35.0 3.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4203) EamA PF00892.20 RLN36944.1 - 3.5e-08 33.7 11.9 3.5e-08 33.7 11.9 5.1 4 2 1 5 5 5 2 EamA-like transporter family PUNUT PF16913.5 RLN36944.1 - 0.0011 18.3 12.1 0.0011 18.3 12.1 2.1 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport DUF3318 PF11780.8 RLN36944.1 - 6.9 6.6 6.1 1.1 9.2 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) G_path_suppress PF15991.5 RLN36944.1 - 9.3 6.3 14.5 15 5.7 14.5 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor FAM183 PF14886.6 RLN36945.1 - 3.2e-06 27.8 0.2 5.6e-06 27.0 0.2 1.4 1 0 0 1 1 1 1 FAM183A and FAM183B related HTH_Tnp_Tc5 PF03221.16 RLN36946.1 - 3.9e-07 30.0 0.1 6e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Pec_lyase_C PF00544.19 RLN36947.1 - 1.3e-10 41.2 7.7 1.3e-10 41.2 7.7 2.4 2 1 0 2 2 2 1 Pectate lyase Beta_helix PF13229.6 RLN36947.1 - 0.0025 17.7 11.0 0.0025 17.7 2.2 2.5 1 1 1 2 2 2 2 Right handed beta helix region MSA-2c PF12238.8 RLN36947.1 - 2.8 7.9 7.5 4.4 7.3 7.5 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c CPSF100_C PF13299.6 RLN36947.1 - 3.1 7.9 4.1 5.1 7.3 4.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Pkinase PF00069.25 RLN36948.1 - 1.8e-44 152.1 0.0 3.5e-32 111.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN36948.1 - 1.1e-18 67.5 0.0 6.4e-13 48.6 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RLN36948.1 - 9.9e-06 25.1 0.0 0.0048 16.2 0.0 2.1 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 RLN36948.1 - 0.19 11.6 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family PDZ PF00595.24 RLN36949.1 - 2.1e-12 47.2 0.0 0.057 13.8 0.0 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 RLN36949.1 - 6.7e-12 45.1 0.2 0.025 14.4 0.0 4.3 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 RLN36949.1 - 0.00029 21.1 0.3 6.8 7.1 0.1 4.0 4 0 0 4 4 4 2 PDZ domain NtCtMGAM_N PF16863.5 RLN36949.1 - 0.01 16.0 0.1 0.059 13.6 0.2 2.2 2 0 0 2 2 2 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase CSRNP_N PF16019.5 RLN36950.1 - 0.00037 20.5 1.1 0.0027 17.6 1.1 2.0 1 1 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus MFS_1 PF07690.16 RLN36951.1 - 3.2e-08 32.9 36.8 8.2e-05 21.7 15.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 RLN36953.1 - 2e-63 214.2 0.0 2.4e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN36953.1 - 1.2e-23 83.8 0.3 4.3e-23 81.9 0.3 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN36953.1 - 4.1e-05 23.6 0.5 7.7e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN36953.1 - 0.0015 17.4 0.4 0.028 13.2 0.1 2.0 1 1 1 2 2 2 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 RLN36953.1 - 0.014 14.4 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 RLN36953.1 - 0.016 14.5 0.1 0.023 14.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RLN36953.1 - 0.048 13.3 0.1 0.075 12.6 0.1 1.3 1 0 0 1 1 1 0 RIO1 family DUF1849 PF08904.11 RLN36953.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1849) Kinase-like PF14531.6 RLN36953.1 - 0.18 11.1 0.2 0.55 9.5 0.2 1.8 1 1 0 1 1 1 0 Kinase-like Pkinase PF00069.25 RLN36954.1 - 1.5e-45 155.6 0.0 1.9e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN36954.1 - 1.3e-32 113.1 0.0 1.6e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN36954.1 - 0.00065 18.6 0.0 0.0014 17.5 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 RLN36954.1 - 0.0067 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN36954.1 - 0.057 12.8 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SSF PF00474.17 RLN36956.1 - 1.3e-23 83.5 17.9 1.2e-21 77.1 9.6 2.2 2 0 0 2 2 2 2 Sodium:solute symporter family Holin_BlyA PF05102.12 RLN36956.1 - 1.8 8.6 3.9 31 4.6 0.6 2.7 2 0 0 2 2 2 0 holin, BlyA family PrgI PF12666.7 RLN36957.1 - 0.007 17.1 0.2 0.038 14.7 0.0 1.9 2 0 0 2 2 2 1 PrgI family protein DUF3278 PF11683.8 RLN36957.1 - 0.038 14.1 1.5 3.6 7.7 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3278) CSRNP_N PF16019.5 RLN36958.1 - 0.038 13.9 0.0 0.066 13.1 0.0 1.4 1 1 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF5338 PF17273.2 RLN36959.1 - 0.042 13.9 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5338) PG_binding_3 PF09374.10 RLN36960.1 - 0.099 12.9 0.3 0.19 12.0 0.3 1.4 1 0 0 1 1 1 0 Predicted Peptidoglycan domain FAM76 PF16046.5 RLN36960.1 - 0.37 10.1 6.2 0.43 9.9 6.2 1.1 1 0 0 1 1 1 0 FAM76 protein DUF390 PF04094.14 RLN36960.1 - 7.4 4.7 11.3 8.8 4.5 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) DDE_1 PF03184.19 RLN36963.1 - 2.3e-15 56.7 0.1 3.2e-15 56.2 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_11 PF08279.12 RLN36963.1 - 0.056 13.4 0.3 0.39 10.7 0.0 2.3 2 0 0 2 2 2 0 HTH domain PPR_2 PF13041.6 RLN36965.1 - 3.2e-47 158.5 8.3 2.9e-15 56.2 0.0 9.5 6 3 4 10 10 10 9 PPR repeat family PPR PF01535.20 RLN36965.1 - 3.1e-41 136.8 15.4 5.7e-08 32.5 0.0 12.4 12 1 0 12 12 12 9 PPR repeat PPR_1 PF12854.7 RLN36965.1 - 5.1e-39 131.6 3.9 1.1e-10 41.1 0.1 10.8 11 0 0 11 11 11 9 PPR repeat PPR_3 PF13812.6 RLN36965.1 - 3.1e-38 129.7 5.0 2e-08 34.1 0.0 8.6 6 2 2 8 8 8 7 Pentatricopeptide repeat domain PPR_long PF17177.4 RLN36965.1 - 8.9e-20 71.0 13.5 1e-12 47.9 0.8 4.7 2 2 3 5 5 5 4 Pentacotripeptide-repeat region of PRORP Vps39_1 PF10366.9 RLN36965.1 - 0.00013 22.2 0.9 3.2 8.1 0.1 4.2 3 0 0 3 3 3 2 Vacuolar sorting protein 39 domain 1 T2SSM PF04612.12 RLN36965.1 - 2.2 8.3 5.2 0.51 10.4 0.5 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M TPR_14 PF13428.6 RLN36965.1 - 7.9 7.6 25.5 6.3 7.9 0.0 7.8 7 2 2 9 9 9 0 Tetratricopeptide repeat BT1 PF03092.16 RLN36966.1 - 2.2e-14 52.6 11.8 3.9e-12 45.2 0.6 3.5 3 1 0 3 3 3 3 BT1 family FYVE PF01363.21 RLN36967.1 - 1e-09 38.4 8.0 3e-09 36.9 8.0 1.8 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 RLN36967.1 - 7.3e-07 29.9 0.1 3.4e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 RLN36967.1 - 0.019 15.3 0.0 0.042 14.2 0.0 1.5 1 0 0 1 1 1 0 GAF domain zf-RING_5 PF14634.6 RLN36967.1 - 0.14 12.1 7.9 0.35 10.9 7.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 RLN36967.1 - 0.65 10.4 7.5 2.1 8.7 7.5 2.0 1 0 0 1 1 1 0 Ring finger domain FYVE PF01363.21 RLN36968.1 - 1e-09 38.4 12.1 2.5e-09 37.1 12.1 1.7 1 0 0 1 1 1 1 FYVE zinc finger GAF_2 PF13185.6 RLN36968.1 - 3.9e-08 33.7 0.1 1.4e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 RLN36968.1 - 1.3e-05 25.8 0.0 5.2e-05 23.9 0.0 2.1 1 0 0 1 1 1 1 GAF domain Prok-RING_4 PF14447.6 RLN36968.1 - 0.043 13.7 3.6 0.14 12.0 3.6 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 SR-25 PF10500.9 RLN36968.1 - 1.3 8.5 18.2 0.086 12.4 12.0 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-RING_2 PF13639.6 RLN36968.1 - 5.5 7.4 11.1 17 5.9 11.1 1.9 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 RLN36968.1 - 9.9 6.3 8.0 23 5.1 8.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger FYVE PF01363.21 RLN36969.1 - 1e-09 38.4 13.0 2.2e-09 37.3 13.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger IFT57 PF10498.9 RLN36969.1 - 0.0075 15.3 0.9 0.013 14.5 0.9 1.3 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 GAF_2 PF13185.6 RLN36969.1 - 0.061 13.6 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 GAF domain zf-RING_5 PF14634.6 RLN36969.1 - 0.97 9.5 14.3 1.9 8.5 14.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-B_box PF00643.24 RLN36969.1 - 1.4 9.1 7.9 6.2 7.1 7.9 2.1 1 1 0 1 1 1 0 B-box zinc finger PHO4 PF01384.20 RLN36971.1 - 1.2e-15 57.4 8.7 1.4e-15 57.2 8.7 1.0 1 0 0 1 1 1 1 Phosphate transporter family ABC2_membrane PF01061.24 RLN36972.1 - 6e-38 130.4 21.2 6e-38 130.4 21.2 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 RLN36972.1 - 4.2e-07 29.4 15.9 4.2e-07 29.4 15.9 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC_tran PF00005.27 RLN36972.1 - 0.0045 17.5 0.0 0.0074 16.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_2 PF12679.7 RLN36972.1 - 0.078 12.2 9.8 1.4 8.1 8.9 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein ADH_zinc_N_2 PF13602.6 RLN36973.1 - 2.4e-15 57.8 0.0 2.6e-15 57.6 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN36974.1 - 1.6e-23 84.2 0.1 3.9e-23 83.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 RLN36974.1 - 6.8e-15 55.2 0.6 6.8e-15 55.2 0.6 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN36974.1 - 2.1e-09 37.2 0.0 4.7e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF2855 PF11017.8 RLN36974.1 - 0.0018 18.1 0.3 0.0031 17.3 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2855) TrkA_N PF02254.18 RLN36974.1 - 0.024 14.9 0.1 0.041 14.2 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 RLN36974.1 - 0.04 13.2 0.6 0.065 12.5 0.6 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Tmemb_cc2 PF10267.9 RLN36996.1 - 0.00047 19.4 0.2 0.0007 18.8 0.2 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein TMF_TATA_bd PF12325.8 RLN36996.1 - 0.0061 16.8 4.8 0.0061 16.8 4.8 1.7 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 RLN36996.1 - 0.012 15.9 11.2 0.012 15.9 11.2 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TMCO5 PF14992.6 RLN36996.1 - 2.6 7.5 6.0 0.28 10.7 1.7 1.5 2 0 0 2 2 2 0 TMCO5 family Nup35_RRM PF05172.13 RLN37005.1 - 1.1e-16 60.6 0.0 3.2e-16 59.1 0.0 1.8 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 RLN37005.1 - 1.8e-09 37.5 0.0 3.6e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Brix PF04427.18 RLN37006.1 - 2.8e-29 102.6 1.1 5.1e-29 101.8 1.1 1.4 1 0 0 1 1 1 1 Brix domain Suf PF05843.14 RLN37006.1 - 0.00051 20.1 1.1 0.00088 19.3 1.1 1.3 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) eIF3g PF12353.8 RLN37006.1 - 0.075 13.4 1.7 0.15 12.4 1.7 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G RRP14 PF15459.6 RLN37006.1 - 3.8 8.2 8.5 3.9 8.1 0.1 2.7 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 Cytochrom_C PF00034.21 RLN37007.1 - 7.3e-16 59.1 0.4 1.1e-15 58.6 0.4 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 RLN37007.1 - 1.6e-06 28.3 2.9 6.5e-06 26.4 2.9 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 RLN37007.1 - 0.0026 17.5 0.5 0.0055 16.4 0.3 1.6 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome_P460 PF16694.5 RLN37007.1 - 0.15 12.4 0.5 2 8.8 0.2 2.0 2 0 0 2 2 2 0 Cytochrome P460 stn_TNFRSF12A PF12191.8 RLN37008.1 - 0.021 15.0 0.9 0.045 14.0 0.1 1.9 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Kinesin_assoc PF16183.5 RLN37008.1 - 0.025 14.7 1.6 0.048 13.8 0.1 2.0 1 1 1 2 2 2 0 Kinesin-associated Bacillus_HBL PF05791.11 RLN37008.1 - 0.06 13.2 4.4 0.11 12.4 4.4 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) TMPIT PF07851.13 RLN37008.1 - 1.3 8.2 4.6 2 7.6 4.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein F5_F8_type_C PF00754.25 RLN37034.1 - 0.00068 19.8 0.0 0.00092 19.3 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain CS PF04969.16 RLN37035.1 - 2.2e-07 31.8 0.3 2.2e-07 31.8 0.3 1.5 2 0 0 2 2 2 1 CS domain FERM_f0 PF16511.5 RLN37035.1 - 0.045 14.1 0.2 0.15 12.4 0.1 1.9 2 0 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM RAP-1 PF03085.15 RLN37035.1 - 0.048 13.3 0.1 0.071 12.8 0.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SIL1 PF16782.5 RLN37036.1 - 0.078 12.2 0.0 0.083 12.1 0.0 1.1 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 DUF104 PF01954.16 RLN37036.1 - 0.14 12.6 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF104 PHD PF00628.29 RLN37037.1 - 3.5e-07 30.0 7.4 6.7e-07 29.1 7.4 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 RLN37037.1 - 0.0081 16.4 2.2 0.016 15.5 2.2 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain Forkhead PF00250.18 RLN37037.1 - 0.014 15.7 0.2 0.031 14.5 0.2 1.5 1 1 0 1 1 1 0 Forkhead domain LRR19-TM PF15176.6 RLN37039.1 - 0.12 12.4 0.1 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain LRR19-TM PF15176.6 RLN37041.1 - 0.1 12.6 0.1 1.2 9.2 0.0 2.7 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain Strep_SA_rep PF06696.11 RLN37043.1 - 0.0017 18.2 6.6 0.0071 16.3 6.6 2.1 1 0 0 1 1 1 1 Streptococcal surface antigen repeat DUF349 PF03993.12 RLN37043.1 - 3.4 8.0 11.6 31 5.0 11.6 2.7 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) RabGAP-TBC PF00566.18 RLN37044.1 - 2.5e-21 76.3 0.5 4.6e-09 36.2 0.4 3.3 1 1 2 3 3 3 3 Rab-GTPase-TBC domain Gp58 PF07902.11 RLN37044.1 - 0.12 10.6 0.5 0.24 9.7 0.5 1.4 1 0 0 1 1 1 0 gp58-like protein Latarcin PF10279.9 RLN37044.1 - 0.78 10.2 2.7 1.9 8.9 2.7 1.7 1 0 0 1 1 1 0 Latarcin precursor Transcrip_act PF04949.13 RLN37044.1 - 0.79 9.6 6.2 1.1 9.2 5.3 1.6 2 0 0 2 2 2 0 Transcriptional activator WD40 PF00400.32 RLN37045.1 - 5.6e-10 39.6 8.9 0.011 16.5 0.2 7.1 7 0 0 7 7 7 3 WD domain, G-beta repeat Acetyltransf_3 PF13302.7 RLN37045.1 - 2.9e-06 28.0 0.1 7.7e-06 26.6 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ANAPC4_WD40 PF12894.7 RLN37045.1 - 0.012 15.9 3.4 3.5 8.0 0.2 4.5 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Acetyltransf_1 PF00583.25 RLN37045.1 - 0.18 12.1 0.0 0.5 10.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family LCAT PF02450.15 RLN37046.1 - 9.8e-05 21.7 0.7 0.37 9.9 0.1 2.2 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 RLN37046.1 - 0.00072 20.2 0.3 2.2 8.8 0.0 2.8 2 1 0 2 2 2 2 Alpha/beta hydrolase family Plug PF07715.15 RLN37046.1 - 0.012 16.2 0.1 1.2 9.7 0.0 2.6 2 0 0 2 2 2 0 TonB-dependent Receptor Plug Domain PGAP1 PF07819.13 RLN37046.1 - 0.016 14.9 0.1 8 6.1 0.0 2.5 2 0 0 2 2 2 0 PGAP1-like protein Hydrolase_4 PF12146.8 RLN37046.1 - 0.078 12.2 0.1 14 4.9 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF900 PF05990.12 RLN37046.1 - 0.13 11.8 0.0 20 4.6 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) SWIM PF04434.17 RLN37046.1 - 0.38 10.5 3.3 11 5.8 0.2 2.7 2 0 0 2 2 2 0 SWIM zinc finger Yeast-kill-tox PF09207.11 RLN37046.1 - 9.8 6.9 9.9 18 6.0 0.3 3.2 3 0 0 3 3 3 0 Yeast killer toxin DUF2828 PF11443.8 RLN37047.1 - 0.0032 15.7 1.5 0.0036 15.5 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) Conotoxin PF02950.17 RLN37047.1 - 0.1 13.6 1.1 0.35 11.9 1.1 2.0 1 0 0 1 1 1 0 Conotoxin DUF1676 PF07898.13 RLN37047.1 - 0.11 12.5 0.7 0.2 11.7 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) U79_P34 PF03064.16 RLN37047.1 - 0.26 10.6 9.1 0.42 9.9 9.1 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Presenilin PF01080.17 RLN37047.1 - 0.88 8.3 2.9 1.1 8.0 2.9 1.3 1 0 0 1 1 1 0 Presenilin DDRGK PF09756.9 RLN37047.1 - 0.99 9.0 15.9 1.5 8.4 15.9 1.2 1 0 0 1 1 1 0 DDRGK domain Connexin PF00029.19 RLN37047.1 - 1 9.1 2.6 1.6 8.4 2.6 1.2 1 0 0 1 1 1 0 Connexin CDC45 PF02724.14 RLN37047.1 - 2.7 6.2 9.5 3.7 5.7 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Afi1 PF07792.12 RLN37048.1 - 0.023 15.2 0.0 0.051 14.1 0.0 1.6 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PMSI1 PF15322.6 RLN37048.1 - 0.026 14.0 3.5 0.042 13.3 3.5 1.3 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative VIR_N PF15912.5 RLN37048.1 - 0.046 13.3 11.1 0.083 12.5 11.1 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Rrn6 PF10214.9 RLN37048.1 - 0.17 10.4 5.5 0.19 10.2 5.5 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RPN2_C PF18004.1 RLN37048.1 - 0.8 9.6 11.4 1.6 8.6 11.4 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4337 PF14235.6 RLN37048.1 - 1.5 9.0 9.9 2.6 8.1 9.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) PPL5 PF18168.1 RLN37048.1 - 1.8 7.8 10.0 2.9 7.1 10.0 1.3 1 0 0 1 1 1 0 Prim-pol family 5 DUF2828 PF11443.8 RLN37048.1 - 1.9 6.5 12.3 2.6 6.0 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Connexin PF00029.19 RLN37048.1 - 2.9 7.6 9.0 1.5 8.5 7.0 1.5 2 0 0 2 2 2 0 Connexin Presenilin PF01080.17 RLN37048.1 - 2.9 6.6 8.8 4.2 6.0 8.8 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 RLN37048.1 - 3.2 5.9 15.4 4.6 5.4 15.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1682 PF07946.14 RLN37048.1 - 5 6.2 17.9 7.1 5.7 17.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DDRGK PF09756.9 RLN37048.1 - 7 6.2 24.3 11 5.6 24.3 1.3 1 0 0 1 1 1 0 DDRGK domain Nucleo_P87 PF07267.11 RLN37048.1 - 8.3 5.1 11.3 10 4.9 11.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Glyco_hydro_3_C PF01915.22 RLN37049.1 - 1.7e-38 132.6 0.0 3.1e-38 131.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RLN37049.1 - 2.1e-12 46.9 0.2 4.7e-12 45.8 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Cuticle_1 PF08140.11 RLN37049.1 - 0.097 12.7 0.0 0.4 10.8 0.0 2.1 1 0 0 1 1 1 0 Crustacean cuticle protein repeat CARDB PF07705.11 RLN37049.1 - 0.17 12.1 1.0 0.5 10.6 0.1 2.1 2 0 0 2 2 2 0 CARDB DUF2458 PF10454.9 RLN37053.1 - 1.3 8.6 18.8 0.18 11.5 6.8 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2458) ALMT PF11744.8 RLN37053.1 - 7.1 5.3 11.0 15 4.3 11.0 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter MRPL52 PF18699.1 RLN37053.1 - 8.1 6.7 17.7 8.3 6.7 0.5 4.4 5 0 0 5 5 5 0 Mitoribosomal protein mL52 GAS PF13851.6 RLN37053.1 - 9.6 5.5 29.3 1.8 7.9 17.8 2.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding cNMP_binding PF00027.29 RLN37054.1 - 2.4e-11 43.6 0.0 4.5e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain FlbT PF07378.11 RLN37054.1 - 0.012 15.7 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Flagellar protein FlbT YTH PF04146.15 RLN37055.1 - 1.5e-16 60.8 0.3 3.5e-08 33.6 0.2 2.2 2 0 0 2 2 2 2 YT521-B-like domain Thioredoxin PF00085.20 RLN37056.1 - 8.2e-29 99.6 0.0 1.6e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 RLN37056.1 - 1.9e-06 28.3 0.1 2.6e-05 24.6 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 RLN37056.1 - 0.00046 20.1 0.0 0.00071 19.5 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 RLN37056.1 - 0.00069 19.1 0.0 0.0018 17.7 0.0 1.8 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 RLN37056.1 - 0.0051 16.8 0.0 0.0094 16.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.6 RLN37056.1 - 0.0085 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 RLN37056.1 - 0.013 15.9 0.0 0.16 12.3 0.0 2.3 2 1 1 3 3 3 0 Thioredoxin-like Redoxin PF08534.10 RLN37056.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Redoxin DDE_Tnp_1_2 PF13586.6 RLN37056.1 - 0.019 15.3 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain Thioredoxin_7 PF13899.6 RLN37056.1 - 0.029 14.6 0.0 0.069 13.3 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_6 PF13848.6 RLN37056.1 - 0.036 14.0 0.0 0.065 13.1 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.14 RLN37056.1 - 0.05 14.0 0.1 0.11 12.9 0.0 1.6 2 0 0 2 2 1 0 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 RLN37056.1 - 0.11 12.7 1.5 0.14 12.3 0.1 2.1 2 1 0 2 2 2 0 Glutaredoxin AhpC-TSA PF00578.21 RLN37056.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family KIX_2 PF16987.5 RLN37057.1 - 5.7e-08 32.6 0.6 2.6e-07 30.5 0.2 2.2 2 0 0 2 2 2 1 KIX domain SOBP PF15279.6 RLN37057.1 - 2.3 8.8 7.7 0.095 13.3 1.0 1.8 2 0 0 2 2 2 0 Sine oculis-binding protein Piwi PF02171.17 RLN37082.1 - 8.1e-91 304.4 0.0 1.3e-90 303.8 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 RLN37082.1 - 1.6e-16 60.3 0.0 3.3e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 RLN37082.1 - 1e-15 58.6 0.0 3.2e-15 57.0 0.0 1.9 1 1 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 RLN37082.1 - 3.3e-15 55.5 0.0 6.4e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 RLN37082.1 - 5.8e-13 49.0 0.0 1.7e-12 47.5 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 RLN37082.1 - 5.8e-12 45.7 0.3 3.9e-11 43.0 0.0 2.4 2 0 0 2 2 2 1 Mid domain of argonaute Aldedh PF00171.22 RLN37083.1 - 3.1e-78 263.3 0.0 3.9e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NTP_transf_2 PF01909.23 RLN37085.1 - 1.6e-10 41.1 0.0 3.7e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 RLN37085.1 - 3.3e-07 30.4 0.0 9e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 RLN37085.1 - 0.0075 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DNA_pol_B_palm PF14792.6 RLN37085.1 - 0.016 15.4 0.0 0.048 13.9 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase beta palm COPI_assoc PF08507.10 RLN37086.1 - 5.5e-09 36.2 3.8 7e-09 35.8 3.8 1.1 1 0 0 1 1 1 1 COPI associated protein Spt20 PF12090.8 RLN37087.1 - 0.32 10.6 8.7 0.45 10.1 8.7 1.2 1 0 0 1 1 1 0 Spt20 family COesterase PF00135.28 RLN37088.1 - 6.1e-58 196.9 1.1 1.6e-57 195.6 1.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RLN37088.1 - 0.033 14.0 0.2 0.15 11.9 0.1 2.2 2 1 0 2 2 2 0 alpha/beta hydrolase fold PH PF00169.29 RLN37089.1 - 1.5e-19 70.4 1.2 4.5e-09 36.7 0.1 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 RLN37089.1 - 7.3e-05 23.1 9.1 0.00035 20.9 0.1 3.7 3 1 0 3 3 3 1 Pleckstrin homology domain Chalcone PF02431.15 RLN37089.1 - 0.0071 15.8 0.0 2.8 7.3 0.0 2.5 2 0 0 2 2 2 2 Chalcone-flavanone isomerase PH_8 PF15409.6 RLN37089.1 - 0.0085 16.4 1.3 7.1 7.0 0.0 3.1 3 1 0 3 3 3 2 Pleckstrin homology domain RNA_pol_3_Rpc31 PF11705.8 RLN37089.1 - 0.076 13.3 16.3 0.022 15.0 9.4 2.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.14 RLN37089.1 - 0.76 8.0 20.3 2 6.6 20.3 1.6 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 RLN37089.1 - 2.4 8.0 16.5 4.9 7.0 12.4 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region SGT1 PF07093.11 RLN37089.1 - 5.5 5.3 11.1 10 4.4 11.1 1.3 1 0 0 1 1 1 0 SGT1 protein DUF2457 PF10446.9 RLN37089.1 - 9.6 5.2 37.5 0.063 12.4 28.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Ank_2 PF12796.7 RLN37090.1 - 3.3e-38 130.2 3.0 2.3e-08 34.5 0.0 7.3 4 2 4 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN37090.1 - 2.4e-30 104.5 12.7 8.6e-07 29.4 0.0 11.4 6 3 6 13 13 13 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN37090.1 - 4.4e-29 100.2 13.8 0.036 14.4 0.1 13.2 4 2 9 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN37090.1 - 1.4e-22 77.3 3.2 2.6 8.9 0.0 14.1 11 4 5 16 16 16 4 Ankyrin repeat Ank PF00023.30 RLN37090.1 - 1.9e-06 28.1 1.5 54 4.5 0.0 8.7 6 4 2 8 8 8 0 Ankyrin repeat DUF1843 PF08898.10 RLN37090.1 - 0.024 15.1 0.2 35 5.0 0.0 5.2 7 0 0 7 7 7 0 Domain of unknown function (DUF1843) EMC3_TMCO1 PF01956.16 RLN37091.1 - 0.068 12.9 2.1 0.47 10.2 0.5 2.4 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like HA PF03457.14 RLN37092.1 - 1.1e-20 73.7 0.2 6.8e-07 29.5 0.0 3.2 3 0 0 3 3 3 3 Helicase associated domain Pkinase PF00069.25 RLN37093.1 - 9.3e-52 176.0 0.0 1.5e-51 175.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN37093.1 - 6.7e-46 156.7 0.0 9e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PAP_PilO PF06864.12 RLN37093.1 - 0.0011 17.9 0.1 0.0021 17.0 0.1 1.3 1 0 0 1 1 1 1 Pilin accessory protein (PilO) EF-hand_7 PF13499.6 RLN37093.1 - 0.045 14.2 0.0 0.098 13.1 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 RLN37093.1 - 0.069 13.1 0.0 0.23 11.5 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain FixS PF03597.15 RLN37093.1 - 0.088 12.5 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type LRR_8 PF13855.6 RLN37094.1 - 9.6e-36 121.4 7.7 1.7e-11 43.7 0.0 3.4 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 RLN37094.1 - 2.7e-19 68.9 0.1 4.6e-06 26.9 0.1 4.1 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN37094.1 - 5.4e-09 35.8 1.8 0.00071 19.1 0.2 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 RLN37094.1 - 8.9e-08 31.7 1.2 2.6 9.0 0.2 6.3 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 RLN37094.1 - 1.1e-05 25.1 3.6 4.8 7.5 0.0 6.1 7 0 0 7 7 7 2 Leucine Rich repeat T6SS_VipA PF05591.12 RLN37094.1 - 0.021 14.6 1.1 0.28 11.0 0.0 2.6 1 1 2 3 3 3 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 LCM PF04072.14 RLN37095.1 - 1.7e-19 70.5 0.1 3e-19 69.7 0.1 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Acetyltransf_1 PF00583.25 RLN37095.1 - 4.4e-13 49.5 0.0 8.9e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RLN37095.1 - 3.2e-11 43.5 0.0 6.8e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RLN37095.1 - 1.8e-09 37.6 0.0 3.5e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN37095.1 - 0.0006 19.7 0.0 0.002 18.1 0.0 1.8 1 0 0 1 1 1 1 FR47-like protein ABC_membrane PF00664.23 RLN37107.1 - 1.8e-61 208.2 30.1 3.9e-36 125.1 7.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN37107.1 - 7.2e-49 165.8 0.0 2.6e-27 96.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN37107.1 - 1.7e-08 34.2 3.2 0.007 15.8 0.0 4.1 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RLN37107.1 - 2.9e-07 30.6 0.0 0.0091 16.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 RLN37107.1 - 2e-05 24.2 1.5 0.028 14.2 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN37107.1 - 3.2e-05 23.9 2.9 0.01 15.8 0.2 3.1 3 0 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 RLN37107.1 - 3.5e-05 23.9 0.2 0.002 18.2 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_21 PF13304.6 RLN37107.1 - 0.00029 20.8 2.3 2.3 7.9 0.0 3.6 3 1 1 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DEAD PF00270.29 RLN37107.1 - 0.00052 19.8 0.0 0.0017 18.2 0.0 1.9 2 1 0 2 2 1 1 DEAD/DEAH box helicase AAA_16 PF13191.6 RLN37107.1 - 0.0012 19.3 0.1 0.14 12.5 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 RLN37107.1 - 0.0019 18.7 0.2 1.5 9.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 RLN37107.1 - 0.0071 16.1 0.0 0.18 11.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RLN37107.1 - 0.013 14.8 0.4 0.4 9.9 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.6 RLN37107.1 - 0.032 14.5 0.0 5.3 7.4 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Roc PF08477.13 RLN37107.1 - 0.032 14.4 0.1 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 RLN37107.1 - 0.036 13.8 0.7 12 5.5 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_7 PF12775.7 RLN37107.1 - 0.054 13.0 0.5 3.5 7.1 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 RLN37107.1 - 0.056 12.6 0.5 2.2 7.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 RLN37107.1 - 0.059 12.7 1.2 1.1 8.6 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.6 RLN37107.1 - 0.065 13.5 2.6 3.7 7.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 RLN37107.1 - 0.088 13.4 0.1 10 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 RLN37107.1 - 0.094 12.5 1.2 5.2 6.8 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 RLN37107.1 - 0.1 12.7 2.8 0.33 11.0 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 RLN37107.1 - 0.11 12.2 0.0 28 4.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 RLN37107.1 - 0.16 11.6 1.7 2 8.0 0.1 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 RLN37107.1 - 0.17 11.6 0.1 9.8 5.8 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain Septin PF00735.18 RLN37107.1 - 0.2 10.9 0.3 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Septin ABC_tran PF00005.27 RLN37108.1 - 2.3e-29 102.6 0.0 3.8e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN37108.1 - 4.5e-07 29.5 0.0 0.00011 21.8 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain DEAD PF00270.29 RLN37108.1 - 0.002 17.9 0.1 0.0066 16.2 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase MMR_HSR1 PF01926.23 RLN37108.1 - 0.011 15.8 0.1 0.027 14.6 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 RLN37108.1 - 0.023 14.8 0.9 0.085 12.9 0.2 2.1 2 1 0 2 2 2 0 Helicase HerA, central domain IstB_IS21 PF01695.17 RLN37108.1 - 0.11 12.2 0.2 1 9.0 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.6 RLN37108.1 - 0.13 12.0 0.1 0.32 10.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN37108.1 - 0.14 12.6 0.1 0.24 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain adh_short_C2 PF13561.6 RLN37115.1 - 1.3e-05 24.9 0.1 0.00057 19.5 0.0 3.2 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RLN37115.1 - 0.005 16.3 0.0 2.4 7.6 0.0 3.0 2 1 0 2 2 2 2 short chain dehydrogenase Pkinase PF00069.25 RLN37116.1 - 5.9e-73 245.5 0.0 2.4e-72 243.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN37116.1 - 6.4e-40 137.1 0.0 9.1e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 RLN37116.1 - 2.2e-09 37.0 0.1 5.4e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 AdenylateSensor PF16579.5 RLN37116.1 - 3.6e-09 37.1 1.2 1.6e-08 35.0 1.1 2.1 1 1 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 RLN37116.1 - 4.8e-07 29.4 0.0 9.6e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 RLN37116.1 - 0.00037 20.1 0.1 0.00082 19.0 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 RLN37116.1 - 0.0093 15.9 0.6 0.019 14.9 0.3 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN37116.1 - 0.079 11.9 0.1 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain HTH_Tnp_Tc5 PF03221.16 RLN37117.1 - 2.2e-23 82.1 1.2 3.9e-11 42.8 0.0 2.7 3 0 0 3 3 3 2 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 RLN37117.1 - 0.017 14.8 0.5 1.2 9.0 0.0 3.2 2 1 0 2 2 2 0 helix-turn-helix, Psq domain HTH_Tnp_ISL3 PF13542.6 RLN37117.1 - 0.034 13.6 1.3 7.3 6.1 0.0 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_7 PF02796.15 RLN37117.1 - 0.049 13.7 0.1 0.26 11.4 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_Tnp_1 PF01527.20 RLN37117.1 - 0.57 10.5 3.8 17 5.8 0.0 3.9 4 0 0 4 4 4 0 Transposase HTH_28 PF13518.6 RLN37117.1 - 3.6 7.8 15.0 0.63 10.2 2.3 3.5 4 0 0 4 4 4 0 Helix-turn-helix domain Pkinase PF00069.25 RLN37118.1 - 7.8e-53 179.5 0.0 1.4e-52 178.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN37118.1 - 3e-22 79.1 0.0 5.4e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 RLN37118.1 - 2.5e-14 53.5 1.9 3.9e-06 27.2 0.6 3.6 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN37118.1 - 1.4e-12 46.2 2.2 0.0015 18.0 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 RLN37118.1 - 6e-11 41.4 1.1 0.11 12.5 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 RLN37118.1 - 2.6e-10 39.3 3.0 0.0031 16.9 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 RLN37118.1 - 3.6e-08 33.1 1.4 0.0069 16.2 0.4 4.1 4 0 0 4 4 4 2 EF-hand domain pair Pkinase_fungal PF17667.1 RLN37118.1 - 0.032 13.0 0.8 0.088 11.6 0.0 2.0 3 0 0 3 3 3 0 Fungal protein kinase SPARC_Ca_bdg PF10591.9 RLN37118.1 - 0.036 14.4 0.1 6.1 7.2 0.1 2.6 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.14 RLN37118.1 - 0.071 12.4 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IMUP PF15761.5 RLN37119.1 - 0.085 13.6 22.9 0.13 12.9 4.9 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein PDZ_6 PF17820.1 RLN37119.1 - 0.13 12.2 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 PDZ domain SR-25 PF10500.9 RLN37119.1 - 1.6 8.3 26.3 0.093 12.3 6.6 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein AAA PF00004.29 RLN37120.1 - 2.5e-43 147.6 0.0 4.9e-43 146.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RLN37120.1 - 1.2e-08 34.7 0.1 2.6e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 RLN37120.1 - 1.1e-05 25.7 0.4 0.0023 18.2 0.4 2.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 RLN37120.1 - 1.5e-05 24.8 0.0 2.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 RLN37120.1 - 2.7e-05 24.6 2.2 0.0003 21.2 0.3 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 RLN37120.1 - 8.5e-05 22.6 0.1 0.00063 19.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RLN37120.1 - 9.3e-05 22.6 0.0 0.00019 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 RLN37120.1 - 0.00024 20.9 0.0 0.00059 19.6 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 RLN37120.1 - 0.00029 20.1 0.0 0.00058 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 RLN37120.1 - 0.00032 20.9 0.0 0.00058 20.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 RLN37120.1 - 0.00071 18.9 0.1 0.0014 17.9 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 RLN37120.1 - 0.0047 16.5 0.0 0.014 14.9 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 RLN37120.1 - 0.0089 16.6 0.1 0.023 15.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 RLN37120.1 - 0.009 15.7 0.0 0.034 13.8 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain TsaE PF02367.17 RLN37120.1 - 0.032 14.2 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 RLN37120.1 - 0.032 13.8 0.1 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 RLN37120.1 - 0.037 13.5 0.1 0.081 12.4 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 RLN37120.1 - 0.038 14.0 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 RLN37120.1 - 0.045 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 RLN37120.1 - 0.061 13.2 0.2 0.25 11.2 0.2 2.1 1 1 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 RLN37120.1 - 0.065 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 RLN37120.1 - 0.14 12.6 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Cytidylate_kin PF02224.18 RLN37120.1 - 0.14 11.9 0.1 0.28 10.9 0.1 1.5 1 0 0 1 1 1 0 Cytidylate kinase Pyrid_oxidase_2 PF13883.6 RLN37121.1 - 1e-30 106.9 0.2 1.5e-24 86.8 0.0 2.7 1 1 1 2 2 2 2 Pyridoxamine 5'-phosphate oxidase PRMT5 PF05185.16 RLN37121.1 - 0.089 12.6 0.1 39 4.0 0.0 3.8 3 1 1 4 4 4 0 PRMT5 arginine-N-methyltransferase AbiJ_NTD5 PF18865.1 RLN37121.1 - 2.4 8.0 6.1 28 4.6 0.3 4.3 2 1 3 5 5 5 0 AbiJ N-terminal domain 5 DUF2293 PF10056.9 RLN37130.1 - 0.01 16.1 0.6 0.023 15.0 0.3 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2293) TLD PF07534.16 RLN37131.1 - 3e-31 108.5 0.0 4.7e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 TLD PDZ_6 PF17820.1 RLN37131.1 - 0.0017 18.1 0.0 0.89 9.4 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 RLN37131.1 - 0.0042 17.4 0.0 0.054 13.8 0.0 2.3 2 0 0 2 2 2 1 PDZ domain Med3 PF11593.8 RLN37131.1 - 0.094 11.9 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FliD_N PF02465.18 RLN37132.1 - 0.075 13.7 0.3 0.15 12.7 0.3 1.5 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Sigma70_r4 PF04545.16 RLN37144.1 - 0.032 13.7 0.2 0.097 12.2 0.1 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 Pkinase PF00069.25 RLN37145.1 - 0.00011 21.6 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 RLN37146.1 - 6.9e-53 179.7 0.0 1e-52 179.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN37146.1 - 6.7e-33 114.1 0.0 9.9e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN37146.1 - 0.00048 19.5 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RLN37146.1 - 0.0034 16.4 0.0 0.0065 15.5 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RLN37146.1 - 0.0063 16.5 0.2 0.096 12.6 0.0 2.5 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN37146.1 - 0.0089 14.8 0.2 0.029 13.2 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase DUF3645 PF12359.8 RLN37152.1 - 8.9e-06 25.0 0.1 1.6e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) C2 PF00168.30 RLN37153.1 - 5.6e-20 71.6 0.0 7.8e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 C2 domain DUF1084 PF06454.11 RLN37154.1 - 0.0061 16.0 0.8 0.0061 16.0 0.8 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1084) SUR7 PF06687.12 RLN37154.1 - 6.3 6.4 11.8 1.3 8.7 3.1 2.4 2 0 0 2 2 2 0 SUR7/PalI family DJ-1_PfpI PF01965.24 RLN37155.1 - 7.9e-25 87.6 0.0 1e-24 87.2 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 RLN37155.1 - 0.0044 16.6 0.0 0.006 16.2 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain UPRTase PF14681.6 RLN37155.1 - 0.094 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DUF3450 PF11932.8 RLN37158.1 - 0.51 9.6 13.2 0.088 12.1 6.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) YabA PF06156.13 RLN37158.1 - 0.56 10.9 3.2 2.5 8.8 0.1 2.4 2 0 0 2 2 2 0 Initiation control protein YabA Com_YlbF PF06133.11 RLN37158.1 - 1.5 9.5 8.0 6.1 7.5 0.7 2.6 3 0 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA CENP-F_leu_zip PF10473.9 RLN37158.1 - 2.4 8.2 13.6 24 5.0 11.9 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMEM154 PF15102.6 RLN37189.1 - 0.00028 20.8 0.1 0.00051 20.0 0.1 1.5 1 0 0 1 1 1 1 TMEM154 protein family CD34_antigen PF06365.12 RLN37189.1 - 0.098 12.2 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF2615 PF11027.8 RLN37189.1 - 0.2 11.8 1.7 0.33 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) DUF1180 PF06679.12 RLN37189.1 - 3.6 8.0 11.2 0.53 10.7 6.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) Trp_oprn_chp PF09534.10 RLN37190.1 - 0.024 14.4 0.9 0.024 14.4 0.9 1.8 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Gram_pos_anchor PF00746.21 RLN37190.1 - 1.4 8.9 3.5 8.1 6.5 3.5 2.4 1 1 0 1 1 1 0 LPXTG cell wall anchor motif Peptidase_S41 PF03572.18 RLN37191.1 - 0.043 13.4 0.3 0.074 12.6 0.3 1.4 1 0 0 1 1 1 0 Peptidase family S41 GTP_EFTU PF00009.27 RLN37192.1 - 9e-13 48.2 0.7 2.8e-12 46.6 0.0 2.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 RLN37192.1 - 2.1e-07 31.3 0.9 2.1e-07 31.3 0.9 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 RLN37192.1 - 4.7e-06 26.9 0.0 0.00052 20.3 0.0 2.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RLN37192.1 - 6.2e-05 23.1 0.0 0.00018 21.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 RLN37192.1 - 0.00023 21.3 0.8 0.054 13.5 0.8 2.5 1 1 0 1 1 1 1 Dynamin family Roc PF08477.13 RLN37192.1 - 0.06 13.6 0.1 0.25 11.6 0.0 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Mre11_DNA_bind PF04152.14 RLN37193.1 - 6.2e-37 127.5 1.6 6.2e-37 127.5 1.6 3.0 5 0 0 5 5 5 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 RLN37193.1 - 9e-13 49.2 0.2 1.7e-12 48.3 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RLN37193.1 - 0.0011 19.2 0.0 0.037 14.2 0.0 2.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF3246 PF11596.8 RLN37193.1 - 3.3 7.1 15.5 1.1 8.6 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3246) Myb_DNA-binding PF00249.31 RLN37195.1 - 4.2e-37 126.1 6.7 1.8e-13 50.5 0.9 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN37195.1 - 4e-29 100.6 0.2 8.5e-10 38.7 0.0 3.5 2 1 1 3 3 3 3 Myb-like DNA-binding domain PseudoU_synth_2 PF00849.22 RLN37195.1 - 6.5e-06 26.3 0.9 3.5e-05 24.0 0.5 2.4 2 1 0 2 2 2 1 RNA pseudouridylate synthase HMG_box_2 PF09011.10 RLN37195.1 - 0.0011 19.6 2.8 0.0018 18.9 0.4 2.7 3 0 0 3 3 3 1 HMG-box domain HMG_box PF00505.19 RLN37195.1 - 0.01 16.2 2.0 0.02 15.3 0.4 2.4 2 0 0 2 2 2 0 HMG (high mobility group) box TPR_12 PF13424.6 RLN37196.1 - 1.5e-13 50.8 3.2 1e-08 35.4 0.1 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN37196.1 - 0.0041 16.9 2.4 0.13 12.1 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 RLN37196.1 - 0.011 15.8 0.2 0.36 11.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 RLN37196.1 - 0.013 15.7 1.6 0.12 12.7 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN37196.1 - 0.014 15.2 0.1 0.73 9.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat FKS1_dom1 PF14288.6 RLN37196.1 - 0.13 12.6 0.1 0.49 10.7 0.0 1.8 2 0 0 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 TPR_6 PF13174.6 RLN37196.1 - 0.42 11.3 2.4 6.5 7.6 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat FKBP_C PF00254.28 RLN37197.1 - 1.2e-26 92.9 0.0 1.5e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase WD40 PF00400.32 RLN37198.1 - 2.6e-09 37.5 16.1 0.00012 22.8 0.2 6.4 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN37198.1 - 0.00021 21.5 0.0 0.2 12.0 0.0 3.9 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Apolipoprotein PF01442.18 RLN37199.1 - 0.0011 18.9 16.7 0.0096 15.8 10.5 2.4 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain LEA_4 PF02987.16 RLN37199.1 - 0.021 14.9 6.0 0.021 14.9 6.0 3.2 4 0 0 4 4 4 0 Late embryogenesis abundant protein AAA_32 PF13654.6 RLN37199.1 - 0.03 13.1 4.5 0.074 11.8 1.3 2.0 2 0 0 2 2 2 0 AAA domain Phasin_2 PF09361.10 RLN37199.1 - 0.079 13.2 10.6 0.3 11.4 3.7 3.1 2 1 1 3 3 3 0 Phasin protein DUF883 PF05957.13 RLN37199.1 - 0.37 11.4 16.3 1.1 9.9 0.1 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) CENP-K PF11802.8 RLN37199.1 - 0.9 9.1 4.6 0.33 10.5 0.8 1.9 2 1 0 2 2 2 0 Centromere-associated protein K Med6 PF04934.14 RLN37200.1 - 2.1e-35 121.4 0.0 3.8e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 MED6 mediator sub complex component Pkinase PF00069.25 RLN37201.1 - 2.5e-45 154.9 0.0 3.2e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN37201.1 - 1.2e-16 60.8 0.0 2.2e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN37201.1 - 0.026 14.5 5.1 0.15 11.9 0.1 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 RLN37201.1 - 0.03 13.9 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 RLN37201.1 - 0.074 12.4 0.2 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 Kinase-like MtN3_slv PF03083.16 RLN37203.1 - 1.5e-21 76.2 11.7 2.1e-16 59.7 0.6 3.1 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange Exostosin PF03016.15 RLN37203.1 - 1.9e-05 24.0 0.0 3.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Exostosin family Syntaxin-6_N PF09177.11 RLN37204.1 - 0.017 15.7 3.3 2.3 8.8 1.1 3.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Pex19 PF04614.12 RLN37204.1 - 1.8 8.3 4.4 3.3 7.4 4.4 1.3 1 0 0 1 1 1 0 Pex19 protein family DUF4518 PF15008.6 RLN37205.1 - 0.0013 18.0 0.1 0.0017 17.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) SAP PF02037.27 RLN37205.1 - 0.06 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 SAP domain Ank_2 PF12796.7 RLN37206.1 - 1.9e-32 111.7 2.7 2.1e-06 28.2 0.8 7.5 2 1 7 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN37206.1 - 5e-32 109.9 11.5 8.6e-05 23.0 0.4 11.1 10 3 2 12 12 12 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN37206.1 - 5.2e-21 74.4 22.9 0.034 14.5 0.3 13.1 10 3 5 15 15 15 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN37206.1 - 2.1e-20 70.6 6.3 9.3 7.2 0.2 14.6 14 1 1 15 15 15 3 Ankyrin repeat AbiEi_3_N PF17194.4 RLN37206.1 - 0.0044 17.0 6.2 4.2 7.5 0.0 6.2 6 2 2 8 8 8 1 Transcriptional regulator, AbiEi antitoxin N-terminal domain Ank PF00023.30 RLN37206.1 - 0.03 14.8 5.6 12 6.6 0.2 6.9 8 1 0 8 8 8 0 Ankyrin repeat Dioxygenase_C PF00775.21 RLN37208.1 - 6.9e-09 35.4 0.1 1.2e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase SnoaL_2 PF12680.7 RLN37209.1 - 0.12 13.1 0.0 0.32 11.7 0.0 1.8 1 0 0 1 1 1 0 SnoaL-like domain bZIP_1 PF00170.21 RLN37209.1 - 0.9 9.7 12.9 0.23 11.6 9.3 1.9 2 0 0 2 2 2 0 bZIP transcription factor CENP-H PF05837.12 RLN37209.1 - 5.8 7.4 8.2 6.8 7.1 7.1 1.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) bZIP_1 PF00170.21 RLN37212.1 - 0.03 14.4 0.8 0.03 14.4 0.8 1.7 2 0 0 2 2 2 0 bZIP transcription factor PGA2 PF07543.12 RLN37212.1 - 7.6 6.5 12.0 0.079 12.9 3.6 1.9 2 0 0 2 2 2 0 Protein trafficking PGA2 Nop53 PF07767.11 RLN37213.1 - 3.3e-16 59.7 9.9 5.4e-16 59.0 9.9 1.3 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF2570 PF10828.8 RLN37213.1 - 0.22 11.4 7.6 0.55 10.1 7.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) MAT1 PF06391.13 RLN37213.1 - 1.2 9.0 13.4 0.052 13.4 6.5 1.9 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF3671 PF12420.8 RLN37213.1 - 1.5 9.0 5.6 3.3 7.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function RWP-RK PF02042.15 RLN37214.1 - 7.7e-19 67.4 0.1 1.3e-18 66.6 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_6 PF01418.17 RLN37214.1 - 0.11 12.5 0.1 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family tRNA-synt_1d PF00750.19 RLN37215.1 - 4.9e-117 390.8 0.1 1.1e-116 389.6 0.1 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (R) DALR_1 PF05746.15 RLN37215.1 - 5.6e-22 78.2 0.0 1.3e-21 77.0 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 RLN37215.1 - 2.5e-06 28.0 0.0 5.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 RLN37215.1 - 0.0004 19.8 0.0 0.00082 18.8 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.22 RLN37215.1 - 0.0065 14.8 0.1 0.01 14.1 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 RLN37215.1 - 0.081 11.7 0.1 0.16 10.7 0.1 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (M) Pkinase PF00069.25 RLN37238.1 - 2.8e-30 105.6 0.0 6e-25 88.1 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN37238.1 - 3.2e-12 46.3 0.0 8.3e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase HRDC PF00570.23 RLN37238.1 - 2.2e-09 37.2 0.0 5.2e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 HRDC domain KIX_2 PF16987.5 RLN37238.1 - 1.3e-05 25.1 0.1 3.1e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 KIX domain Tup_N PF08581.10 RLN37238.1 - 1.2 9.4 4.1 17 5.8 0.2 2.6 1 1 1 2 2 2 0 Tup N-terminal PRKG1_interact PF15898.5 RLN37238.1 - 8.1 7.4 8.1 2 9.4 1.6 2.9 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain AAA PF00004.29 RLN37239.1 - 2.3e-26 92.8 0.0 1.5e-08 35.2 0.0 3.5 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN37239.1 - 1.1e-08 35.6 5.0 0.00039 20.9 0.1 3.5 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 RLN37239.1 - 1.1e-08 35.4 0.1 0.0013 19.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 RLN37239.1 - 6.2e-06 26.2 0.3 0.051 13.5 0.1 2.7 2 1 0 2 2 2 2 NACHT domain AAA_18 PF13238.6 RLN37239.1 - 7.3e-05 23.3 0.1 0.84 10.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 RLN37239.1 - 0.00019 21.1 0.3 0.34 10.7 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain IstB_IS21 PF01695.17 RLN37239.1 - 0.00023 21.0 0.1 0.011 15.5 0.1 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 RLN37239.1 - 0.00038 20.5 0.0 0.4 10.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 RLN37239.1 - 0.0005 19.6 0.0 0.071 12.6 0.1 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 RLN37239.1 - 0.00062 20.1 0.0 0.1 13.0 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_25 PF13481.6 RLN37239.1 - 0.0012 18.4 1.0 1.2 8.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain ABC_tran PF00005.27 RLN37239.1 - 0.0014 19.2 0.2 0.18 12.3 0.2 2.5 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.6 RLN37239.1 - 0.002 18.3 0.1 0.34 11.1 0.1 2.9 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 RLN37239.1 - 0.0023 17.4 0.6 0.27 10.6 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 RLN37239.1 - 0.0027 17.7 0.0 0.026 14.5 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain Sigma54_activat PF00158.26 RLN37239.1 - 0.0037 17.0 0.1 0.52 10.0 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain TsaE PF02367.17 RLN37239.1 - 0.0043 17.0 0.0 0.028 14.4 0.0 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 RLN37239.1 - 0.0044 16.3 0.3 5.3 6.3 0.1 3.4 3 0 0 3 3 3 0 Zeta toxin DUF815 PF05673.13 RLN37239.1 - 0.0086 15.3 0.7 0.86 8.7 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 RLN37239.1 - 0.0098 15.9 0.2 0.086 12.8 0.1 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 RLN37239.1 - 0.012 15.4 2.0 1 9.2 0.5 2.6 2 0 0 2 2 2 0 AAA+ lid domain AAA_2 PF07724.14 RLN37239.1 - 0.015 15.5 0.0 2.3 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 RLN37239.1 - 0.016 14.4 0.8 3.1 6.9 0.0 2.2 2 0 0 2 2 2 0 TIP49 P-loop domain RsgA_GTPase PF03193.16 RLN37239.1 - 0.017 15.0 0.0 0.4 10.6 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase ATPase PF06745.13 RLN37239.1 - 0.018 14.4 0.4 0.15 11.3 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.6 RLN37239.1 - 0.02 15.2 0.1 0.15 12.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 RLN37239.1 - 0.029 13.4 0.0 0.62 9.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein RuvB_N PF05496.12 RLN37239.1 - 0.054 13.3 0.0 0.68 9.7 0.0 2.7 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Atu4866 PF11512.8 RLN37239.1 - 0.08 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Agrobacterium tumefaciens protein Atu4866 AAA_30 PF13604.6 RLN37239.1 - 0.11 12.2 0.8 15 5.2 0.1 3.0 3 0 0 3 3 3 0 AAA domain Hpr_kinase_C PF07475.12 RLN37239.1 - 0.14 11.6 0.6 5.2 6.6 0.1 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Viral_helicase1 PF01443.18 RLN37239.1 - 0.15 11.8 0.0 13 5.4 0.1 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.18 RLN37239.1 - 0.16 11.8 0.1 1.3 8.9 0.0 2.4 3 0 0 3 3 3 0 Bacterial dnaA protein AAA_10 PF12846.7 RLN37239.1 - 0.43 9.4 0.7 3.7 6.4 0.0 2.2 2 1 0 2 2 2 0 AAA-like domain CAP_C PF08603.11 RLN37244.1 - 6.4e-51 172.1 1.4 1.9e-50 170.5 1.8 1.5 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.19 RLN37244.1 - 1.2e-24 87.4 0.0 1.7e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.12 RLN37244.1 - 4.7e-05 23.1 1.1 0.00011 21.9 1.1 1.7 1 0 0 1 1 1 1 Tubulin binding cofactor C RNA_lig_T4_1 PF09511.10 RLN37244.1 - 0.073 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA ligase Peptidase_C48 PF02902.19 RLN37245.1 - 2e-10 40.9 0.3 4.7e-10 39.7 0.3 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GTP-bdg_N PF13167.6 RLN37245.1 - 0.025 15.2 0.0 1.1 10.0 0.0 2.7 2 0 0 2 2 2 0 GTP-binding GTPase N-terminal DUF5559 PF17714.1 RLN37245.1 - 0.18 11.7 1.3 0.41 10.5 1.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5559) GEN1_C PF18380.1 RLN37245.1 - 0.26 12.2 1.8 0.96 10.4 1.8 1.9 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain ABC_tran PF00005.27 RLN37246.1 - 1.2e-16 61.5 0.0 1.9e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 RLN37246.1 - 0.0009 18.9 0.1 0.0022 17.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN37246.1 - 0.0033 17.8 0.0 0.0052 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.20 RLN37246.1 - 0.01 15.0 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit RsgA_GTPase PF03193.16 RLN37246.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase DUF815 PF05673.13 RLN37246.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 RLN37246.1 - 0.02 15.2 0.1 0.042 14.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 RLN37246.1 - 0.058 12.8 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 RLN37246.1 - 0.06 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain Zeta_toxin PF06414.12 RLN37246.1 - 0.11 11.7 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ELO PF01151.18 RLN37247.1 - 6.2e-39 134.0 23.5 1.1e-38 133.2 23.5 1.3 1 1 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 RLN37248.1 - 5.5e-35 121.1 28.2 8.2e-35 120.5 28.2 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family START PF01852.19 RLN37271.1 - 2.6e-26 92.3 0.0 9e-15 54.6 0.0 2.6 2 0 0 2 2 2 2 START domain 2-oxoacid_dh PF00198.23 RLN37271.1 - 4.8e-25 88.4 0.0 1.5e-16 60.5 0.0 2.9 3 0 0 3 3 3 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) PH PF00169.29 RLN37271.1 - 3.4e-14 53.2 0.0 7.4e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN37271.1 - 0.0006 20.2 0.1 0.0047 17.3 0.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain SPR1 PF15356.6 RLN37271.1 - 0.041 14.4 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Psoriasis susceptibility locus 2 Sugar_tr PF00083.24 RLN37273.1 - 2.2e-111 372.9 26.0 5.3e-84 282.7 13.5 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RLN37273.1 - 1.2e-31 109.9 30.8 9.7e-29 100.4 21.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily PSI_integrin PF17205.3 RLN37273.1 - 0.0074 16.0 0.9 0.015 15.0 0.9 1.5 1 0 0 1 1 1 1 Integrin plexin domain PSI PF01437.25 RLN37273.1 - 0.022 15.3 7.9 0.047 14.2 7.9 1.6 1 0 0 1 1 1 0 Plexin repeat Sugar_tr PF00083.24 RLN37274.1 - 9.6e-115 384.0 23.1 5.1e-89 299.2 11.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RLN37274.1 - 6.7e-32 110.8 32.8 1.9e-30 106.0 15.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 RLN37274.1 - 0.0013 17.2 2.6 0.0013 17.2 2.6 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector PSI PF01437.25 RLN37274.1 - 0.31 11.6 11.7 0.59 10.7 11.7 1.5 1 0 0 1 1 1 0 Plexin repeat Sugar_tr PF00083.24 RLN37275.1 - 1.4e-110 370.3 26.9 3e-85 286.8 14.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RLN37275.1 - 3.9e-30 105.0 33.1 7.3e-27 94.2 22.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily PSI PF01437.25 RLN37275.1 - 0.00099 19.6 7.7 0.0019 18.7 7.7 1.5 1 0 0 1 1 1 1 Plexin repeat PSI_integrin PF17205.3 RLN37275.1 - 0.93 9.3 5.9 1.7 8.4 5.9 1.5 1 0 0 1 1 1 0 Integrin plexin domain WD40 PF00400.32 RLN37276.1 - 4.9e-08 33.5 0.1 1.2e-07 32.3 0.0 1.7 2 0 0 2 2 2 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 RLN37276.1 - 0.0011 18.0 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 RLN37276.1 - 0.0033 17.7 0.0 0.019 15.3 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2285 PF10074.9 RLN37276.1 - 0.047 14.3 5.5 1.6 9.4 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2285) WD40 PF00400.32 RLN37277.1 - 0.00075 20.3 0.6 2.2 9.3 0.0 3.0 3 1 0 3 3 3 2 WD domain, G-beta repeat Voltage_CLC PF00654.20 RLN37278.1 - 4.4e-48 164.3 18.3 6.9e-48 163.7 18.3 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel Abhydrolase_9_N PF15420.6 RLN37278.1 - 0.0073 16.3 4.7 0.095 12.7 1.7 2.4 2 0 0 2 2 2 2 Alpha/beta-hydrolase family N-terminus Sec34 PF04136.15 RLN37278.1 - 9.3 6.1 15.0 6 6.7 1.5 3.2 2 1 0 3 3 3 0 Sec34-like family NAD_binding_10 PF13460.6 RLN37303.1 - 1.9e-06 27.9 0.0 3.5e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 RLN37303.1 - 0.0023 17.1 0.0 0.0094 15.2 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 RLN37303.1 - 0.0065 16.9 0.1 0.044 14.2 0.0 2.4 3 1 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 RLN37303.1 - 0.031 13.8 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.21 RLN37303.1 - 0.032 13.7 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase_Tyr PF07714.17 RLN37304.1 - 8.4e-09 35.1 0.0 5.6e-05 22.5 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN37304.1 - 3.1e-08 33.3 0.0 0.002 17.6 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Ser_hydrolase PF06821.13 RLN37304.1 - 0.008 16.1 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 1 Serine hydrolase Cystatin PF00031.21 RLN37304.1 - 0.029 14.6 0.0 1 9.7 0.0 2.5 1 1 0 2 2 2 0 Cystatin domain Ank_2 PF12796.7 RLN37307.1 - 1.2e-30 105.9 5.4 2.3e-16 60.2 0.4 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN37307.1 - 6.9e-28 96.7 1.5 6.9e-09 36.1 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 RLN37307.1 - 2.2e-26 92.7 0.0 1.6e-09 37.4 0.0 4.2 2 2 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 RLN37307.1 - 2.3e-25 89.5 0.0 5.7e-07 29.2 0.0 4.0 2 2 1 3 3 3 3 Protein kinase domain Ank PF00023.30 RLN37307.1 - 1.9e-21 75.5 9.4 1.7e-05 25.1 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 RLN37307.1 - 1.8e-18 66.4 4.0 6.4e-06 26.4 0.2 4.5 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN37307.1 - 1.6e-17 61.8 1.5 0.08 13.5 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat MtN3_slv PF03083.16 RLN37308.1 - 7.6e-66 218.2 48.2 1.4e-15 57.1 1.8 7.2 7 0 0 7 7 7 6 Sugar efflux transporter for intercellular exchange Fungal_trans PF04082.18 RLN37308.1 - 0.0026 16.8 0.4 0.66 8.9 0.3 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain Prominin PF05478.11 RLN37308.1 - 0.087 10.8 0.7 0.15 10.0 0.7 1.3 1 0 0 1 1 1 0 Prominin TMEMspv1-c74-12 PF11044.8 RLN37308.1 - 0.21 11.6 1.4 0.88 9.6 1.4 2.1 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF2407_C PF13373.6 RLN37308.1 - 3.3 7.9 10.9 8.5 6.5 0.0 5.0 5 2 1 6 6 6 0 DUF2407 C-terminal domain His_Phos_2 PF00328.22 RLN37309.1 - 2.6e-32 112.6 0.0 4.1e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MtN3_slv PF03083.16 RLN37310.1 - 1.4e-11 44.3 8.2 2.6e-11 43.4 2.9 2.4 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange Caa3_CtaG PF09678.10 RLN37310.1 - 0.6 9.5 11.8 0.1 12.1 7.0 1.8 1 1 1 2 2 2 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) MerC PF03203.14 RLN37310.1 - 5.5 7.5 10.9 0.97 9.9 5.9 2.0 2 0 0 2 2 2 0 MerC mercury resistance protein DUF2070 PF09843.9 RLN37310.1 - 5.7 5.1 14.8 6.6 4.9 14.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MtN3_slv PF03083.16 RLN37311.1 - 9.4e-35 118.5 12.9 1.3e-20 73.2 3.2 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RLN37311.1 - 0.013 15.3 7.9 0.12 12.1 0.1 3.3 3 1 0 3 3 3 0 PQ loop repeat QCR10 PF09796.9 RLN37311.1 - 0.17 12.0 1.4 0.39 10.8 0.1 2.3 2 1 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) MtN3_slv PF03083.16 RLN37312.1 - 3.8e-36 123.0 9.0 1e-20 73.5 1.0 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RLN37312.1 - 0.00091 18.9 10.4 0.043 13.6 0.1 3.8 3 1 1 4 4 4 2 PQ loop repeat YtpI PF14007.6 RLN37312.1 - 0.36 11.0 4.5 0.27 11.4 1.5 2.1 1 1 1 2 2 2 0 YtpI-like protein Kinesin PF00225.23 RLN37323.1 - 5e-81 272.2 0.1 5.7e-81 272.0 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN37323.1 - 1.1e-21 77.3 0.0 1.9e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding 6PF2K PF01591.18 RLN37325.1 - 1.5e-69 233.7 0.0 2.3e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 RLN37325.1 - 6.1e-27 94.6 0.0 1.6e-26 93.2 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 RLN37325.1 - 6.4e-07 29.6 0.1 5.2e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arf PF00025.21 RLN37325.1 - 0.15 11.5 0.1 0.43 10.0 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family Ribosomal_L6e PF01159.19 RLN37327.1 - 3.3e-34 117.7 0.1 5.4e-34 117.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e DUF1488 PF07369.11 RLN37328.1 - 0.074 13.0 2.2 0.99 9.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) AAA_lid_9 PF17871.1 RLN37328.1 - 1.8 8.5 9.2 0.2 11.6 4.2 2.0 2 0 0 2 2 2 0 AAA lid domain DHC PF09626.10 RLN37335.1 - 0.93 10.4 6.8 0.79 10.6 0.2 3.7 4 0 0 4 4 4 0 Dihaem cytochrome c TRAUB PF08164.12 RLN37348.1 - 0.24 11.9 1.8 0.33 11.5 0.0 1.9 2 0 0 2 2 2 0 Apoptosis-antagonizing transcription factor, C-terminal Zip PF02535.22 RLN37349.1 - 5.2e-24 85.1 13.9 8.9e-23 81.0 13.9 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.22 RLN37350.1 - 5.6e-17 62.0 12.2 6.8e-17 61.7 12.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter OrfB_Zn_ribbon PF07282.11 RLN37351.1 - 0.035 14.0 1.6 0.5 10.3 1.6 2.5 1 1 0 1 1 1 0 Putative transposase DNA-binding domain Phi-29_GP16_7 PF06720.11 RLN37351.1 - 0.085 12.7 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 CBM_1 PF00734.18 RLN37352.1 - 7.8e-06 25.7 6.0 7.8e-06 25.7 6.0 1.9 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF3580 PF12117.8 RLN37352.1 - 0.028 14.7 0.5 0.032 14.5 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3580) PAP2 PF01569.21 RLN37354.1 - 1.5e-21 76.5 3.3 1.1e-20 73.8 3.3 2.2 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 RLN37354.1 - 0.018 14.7 8.6 0.23 11.1 0.4 2.7 2 1 0 2 2 2 0 PAP2 superfamily DUF872 PF05915.12 RLN37354.1 - 0.04 14.1 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF126 PF01989.16 RLN37354.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Aconitase X swivel domain DUF1488 PF07369.11 RLN37355.1 - 0.066 13.2 1.9 0.99 9.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) AAA_lid_9 PF17871.1 RLN37355.1 - 2.3 8.2 9.0 0.24 11.3 4.0 2.0 2 0 0 2 2 2 0 AAA lid domain MgtC PF02308.16 RLN37357.1 - 0.2 12.0 0.1 0.35 11.2 0.1 1.3 1 0 0 1 1 1 0 MgtC family IMPDH PF00478.25 RLN37358.1 - 1.4e-81 274.2 5.6 1.8e-81 273.9 5.6 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 RLN37358.1 - 1.3e-11 44.8 0.4 5.9e-07 29.8 0.0 3.2 3 0 0 3 3 3 2 CBS domain NMO PF03060.15 RLN37358.1 - 3.7e-10 39.7 8.2 4.3e-05 23.0 4.6 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 RLN37358.1 - 8.5e-06 25.0 2.2 1.4e-05 24.3 2.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.14 RLN37358.1 - 3.6e-05 23.1 1.3 8.4e-05 21.8 0.7 2.0 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 RLN37358.1 - 8.4e-05 22.1 3.1 0.014 14.9 0.3 2.6 2 1 1 3 3 3 2 Histidine biosynthesis protein DUF561 PF04481.12 RLN37358.1 - 0.00017 20.8 4.3 0.0051 16.0 1.8 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF561) QRPTase_C PF01729.19 RLN37358.1 - 0.00032 20.5 0.2 0.00062 19.6 0.2 1.5 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain ThiG PF05690.14 RLN37358.1 - 0.0011 18.3 2.8 0.0023 17.3 1.3 2.2 1 1 0 2 2 2 1 Thiazole biosynthesis protein ThiG B12-binding PF02310.19 RLN37358.1 - 0.0038 17.3 0.2 0.0098 15.9 0.2 1.7 1 0 0 1 1 1 1 B12 binding domain Aldolase PF01081.19 RLN37358.1 - 0.0067 15.9 0.7 0.014 14.8 0.7 1.5 1 0 0 1 1 1 1 KDPG and KHG aldolase TMP-TENI PF02581.17 RLN37358.1 - 0.029 13.7 3.2 0.35 10.2 0.4 2.7 2 1 1 3 3 3 0 Thiamine monophosphate synthase DHO_dh PF01180.21 RLN37358.1 - 0.077 12.2 1.3 0.12 11.5 1.3 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Kinesin PF00225.23 RLN37359.1 - 7e-81 271.7 0.1 7.9e-81 271.6 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN37359.1 - 1.4e-21 77.0 0.0 2.5e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding 6PF2K PF01591.18 RLN37360.1 - 5.5e-65 218.8 0.1 1.6e-64 217.2 0.1 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 RLN37360.1 - 4.7e-27 95.0 0.0 1.3e-26 93.5 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 RLN37360.1 - 8.6e-06 26.0 0.0 0.00032 20.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Ribosomal_L6e PF01159.19 RLN37361.1 - 8.2e-34 116.5 0.1 1.4e-33 115.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e Peptidase_S8 PF00082.22 RLN37362.1 - 1.8e-18 66.8 0.7 2e-18 66.7 0.7 1.0 1 0 0 1 1 1 1 Subtilase family AA_permease_2 PF13520.6 RLN37363.1 - 1e-18 67.4 13.3 1.3e-18 67.1 13.3 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0182 PF03699.13 RLN37363.1 - 0.095 10.8 5.2 0.11 10.6 5.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Tetraspanin PF00335.20 RLN37363.1 - 2.3 7.9 11.2 0.51 10.0 5.9 2.0 2 0 0 2 2 2 0 Tetraspanin family SET PF00856.28 RLN37364.1 - 3.6e-10 40.5 0.0 5.1e-07 30.2 0.0 2.2 1 1 1 2 2 2 2 SET domain AA_permease_2 PF13520.6 RLN37365.1 - 2.9e-45 154.9 40.5 4.5e-45 154.2 40.4 1.3 1 1 0 1 1 1 1 Amino acid permease SHS2_Rpb7-N PF03876.17 RLN37365.1 - 3.3e-12 46.6 0.0 1e-11 45.0 0.0 1.9 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 RLN37365.1 - 1.1e-09 38.4 2.1 1.1e-09 38.4 0.1 2.1 2 0 0 2 2 2 1 S1 RNA binding domain Complex1_LYR PF05347.15 RLN37366.1 - 1.7e-10 40.7 0.6 3.1e-10 40.0 0.6 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 RLN37366.1 - 0.067 13.9 0.1 0.11 13.3 0.1 1.4 1 0 0 1 1 1 0 Complex1_LYR-like Acetyltransf_1 PF00583.25 RLN37367.1 - 3.3e-11 43.4 0.1 4.1e-11 43.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RLN37367.1 - 2.8e-09 37.0 0.1 3.1e-09 36.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN37367.1 - 8.3e-09 35.8 0.1 1.2e-08 35.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN37367.1 - 5.4e-08 32.7 0.0 7.6e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 RLN37367.1 - 0.00018 21.6 0.1 0.00041 20.4 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain bZIP_1 PF00170.21 RLN37393.1 - 1.2e-05 25.3 4.9 2.6e-05 24.2 4.9 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RLN37393.1 - 6.8e-05 22.9 5.1 6.8e-05 22.9 5.1 2.2 2 0 0 2 2 2 1 Basic region leucine zipper RAP1 PF07218.11 RLN37393.1 - 0.0082 14.5 2.7 0.011 14.1 2.7 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) DUF4916 PF16262.5 RLN37393.1 - 0.092 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4916) bZIP_1 PF00170.21 RLN37394.1 - 0.00049 20.1 7.1 0.0014 18.7 7.1 1.8 1 0 0 1 1 1 1 bZIP transcription factor DUF2524 PF10732.9 RLN37394.1 - 0.057 13.7 3.6 0.15 12.4 3.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) Spc7 PF08317.11 RLN37394.1 - 0.53 9.1 6.7 0.82 8.5 6.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein OrfB_Zn_ribbon PF07282.11 RLN37395.1 - 8.5e-05 22.4 1.1 0.00035 20.4 1.1 2.1 1 1 0 1 1 1 1 Putative transposase DNA-binding domain T2SSN PF01203.19 RLN37395.1 - 0.05 13.8 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein N bZIP_2 PF07716.15 RLN37397.1 - 0.0028 17.7 8.4 0.0028 17.7 8.4 5.0 5 0 0 5 5 5 1 Basic region leucine zipper Telethonin PF09470.10 RLN37397.1 - 0.0031 17.4 0.2 0.96 9.3 0.1 2.9 2 0 0 2 2 2 2 Telethonin protein Prp19 PF08606.11 RLN37397.1 - 0.0068 16.4 1.5 2.2 8.3 0.1 3.0 2 0 0 2 2 2 2 Prp19/Pso4-like bZIP_1 PF00170.21 RLN37397.1 - 0.0068 16.5 6.6 0.0068 16.5 6.6 2.6 3 0 0 3 3 3 1 bZIP transcription factor Metallophos PF00149.28 RLN37399.1 - 7.1e-09 36.4 0.4 3.9e-07 30.8 0.4 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RLN37399.1 - 0.16 12.1 6.3 1.6 8.9 6.3 2.3 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Phage_GPO PF05929.11 RLN37400.1 - 0.0084 15.8 0.6 0.013 15.1 0.6 1.2 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase TetR_C_6 PF13977.6 RLN37400.1 - 0.039 14.2 0.8 0.039 14.2 0.8 2.2 2 1 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal PPDK_N PF01326.19 RLN37400.1 - 0.046 13.0 0.1 0.054 12.8 0.1 1.2 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain DUF2431 PF10354.9 RLN37409.1 - 2.4e-31 109.3 0.0 5.9e-31 108.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) zf-C2H2_jaz PF12171.8 RLN37409.1 - 6.1e-10 39.1 17.1 0.04 14.2 0.4 4.7 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 RLN37409.1 - 1.5e-06 28.5 17.7 0.018 15.9 0.8 5.2 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.26 RLN37409.1 - 8.7e-06 25.9 17.3 0.0065 16.9 0.7 5.0 5 0 0 5 5 4 3 Zinc finger, C2H2 type CBFD_NFYB_HMF PF00808.23 RLN37409.1 - 8.8e-06 25.9 2.2 0.00082 19.6 0.2 2.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-met PF12874.7 RLN37409.1 - 2.1e-05 24.7 10.1 0.39 11.2 0.1 4.7 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 RLN37409.1 - 0.0015 19.2 0.7 0.0015 19.2 0.7 3.1 3 0 0 3 3 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 RLN37409.1 - 0.0019 18.1 11.7 0.11 12.5 0.3 4.4 4 0 0 4 4 4 1 C2H2-type zinc finger SmpB PF01668.18 RLN37409.1 - 0.03 14.2 0.4 0.03 14.2 0.4 2.1 3 0 0 3 3 2 0 SmpB protein PyrI_C PF02748.15 RLN37409.1 - 0.092 12.7 1.2 0.96 9.4 0.1 2.7 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_2 PF12756.7 RLN37409.1 - 0.24 11.7 11.5 20 5.6 0.1 4.3 2 2 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 RLN37409.1 - 0.62 10.2 6.4 16 5.7 0.4 3.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-H2C2_2 PF13465.6 RLN37409.1 - 5.3 7.6 8.2 16 6.1 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2HC_2 PF13913.6 RLN37425.1 - 8.1e-12 44.7 11.6 6.5e-07 29.1 3.2 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type FYVE PF01363.21 RLN37425.1 - 6.7e-05 22.9 3.0 0.0022 18.1 0.1 2.3 2 0 0 2 2 2 2 FYVE zinc finger zf-CpG_bind_C PF12269.8 RLN37425.1 - 0.014 15.2 1.6 0.96 9.2 0.0 2.1 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain zf-C2H2 PF00096.26 RLN37425.1 - 0.027 14.9 8.1 2.1 9.0 0.1 3.3 2 1 1 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN37425.1 - 0.034 15.0 11.3 0.27 12.2 0.9 3.2 2 1 1 3 3 3 0 C2H2-type zinc finger zf-CHCC PF10276.9 RLN37425.1 - 0.094 12.8 1.2 0.81 9.8 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger domain zf-RING_7 PF02591.15 RLN37425.1 - 0.1 12.8 0.7 2.4 8.4 0.0 2.4 2 0 0 2 2 2 0 C4-type zinc ribbon domain SWIB PF02201.18 RLN37426.1 - 8.5e-16 57.6 0.0 2.2e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain PA26 PF04636.13 RLN37428.1 - 2.7e-119 399.0 0.0 3.7e-119 398.5 0.0 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) SDA1 PF05285.12 RLN37428.1 - 6.7 6.0 13.1 13 5.1 13.1 1.4 1 0 0 1 1 1 0 SDA1 ANAPC4_WD40 PF12894.7 RLN37429.1 - 2.5e-06 27.7 0.2 0.037 14.3 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RLN37429.1 - 0.0089 16.9 0.2 52 4.9 0.0 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat PQQ PF01011.21 RLN37429.1 - 0.052 13.5 0.0 2.4 8.2 0.0 2.9 2 0 0 2 2 2 0 PQQ enzyme repeat Casc1_N PF15927.5 RLN37430.1 - 1.2e-30 106.7 27.4 1.2e-30 106.7 27.4 2.8 1 1 1 2 2 2 1 Cancer susceptibility candidate 1 N-terminus PAPS_reduct PF01507.19 RLN37431.1 - 5.9e-43 146.9 0.0 8.4e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Glutaredoxin PF00462.24 RLN37431.1 - 3.6e-13 49.5 0.2 1.5e-12 47.5 0.2 2.1 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_2 PF13098.6 RLN37431.1 - 0.079 13.4 0.6 0.76 10.3 0.6 2.4 1 1 0 1 1 1 0 Thioredoxin-like domain EF-hand_1 PF00036.32 RLN37433.1 - 1.8e-38 127.2 8.7 2.3e-07 29.8 0.0 7.3 7 0 0 7 7 7 6 EF hand EF-hand_6 PF13405.6 RLN37433.1 - 1.7e-32 108.6 9.6 6e-06 25.8 0.0 7.3 7 0 0 7 7 7 6 EF-hand domain EF-hand_7 PF13499.6 RLN37433.1 - 4.3e-31 107.2 8.7 2.3e-12 47.2 0.1 4.7 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 RLN37433.1 - 3.8e-25 86.2 9.0 3e-05 23.3 0.3 7.1 7 0 0 7 7 7 5 EF hand EF-hand_8 PF13833.6 RLN37433.1 - 2.1e-18 65.9 17.8 0.0024 17.7 0.0 7.1 5 3 2 7 7 7 5 EF-hand domain pair EF-hand_4 PF12763.7 RLN37433.1 - 5e-06 26.4 8.8 0.11 12.4 0.1 5.5 2 2 3 5 5 5 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RLN37433.1 - 0.00026 21.3 0.8 20 5.5 0.0 4.4 3 1 2 5 5 5 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 RLN37433.1 - 0.006 16.8 0.0 17 5.7 0.0 3.9 4 0 0 4 4 4 0 Dockerin type I domain EF-hand_2 PF09068.11 RLN37433.1 - 0.0066 16.6 0.0 0.51 10.5 0.0 3.3 3 1 0 3 3 3 1 EF hand EF-hand_10 PF14788.6 RLN37433.1 - 0.079 12.8 1.7 15 5.5 0.1 4.1 4 0 0 4 4 4 0 EF hand FG-GAP PF01839.23 RLN37433.1 - 0.74 10.0 6.3 14 5.9 0.1 4.0 4 0 0 4 4 4 0 FG-GAP repeat EF-hand_6 PF13405.6 RLN37451.1 - 3e-22 76.6 4.3 0.00058 19.6 0.0 9.8 9 0 0 9 9 9 5 EF-hand domain EF-hand_1 PF00036.32 RLN37451.1 - 1.4e-20 71.2 0.2 0.0017 17.7 0.0 9.2 11 0 0 11 11 11 4 EF hand EF-hand_7 PF13499.6 RLN37451.1 - 6.1e-19 68.2 3.4 0.00045 20.6 0.1 7.4 8 2 1 9 9 9 5 EF-hand domain pair EF-hand_8 PF13833.6 RLN37451.1 - 6.1e-15 54.8 0.6 0.0056 16.5 0.2 6.4 6 0 0 6 6 6 3 EF-hand domain pair EF-hand_5 PF13202.6 RLN37451.1 - 2.3e-10 39.5 2.8 0.0003 20.1 0.0 6.6 7 0 0 7 7 7 2 EF hand SBP_bac_11 PF13531.6 RLN37452.1 - 7.8e-20 71.6 0.2 9.2e-20 71.4 0.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 RLN37452.1 - 7.2e-08 32.7 0.1 8.6e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 RLN37452.1 - 2.5e-05 23.8 0.1 0.00027 20.4 0.0 2.0 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 RLN37452.1 - 0.0025 17.7 0.2 0.0048 16.8 0.2 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein EF-hand_1 PF00036.32 RLN37453.1 - 7.6e-16 56.4 5.0 6.9e-05 22.1 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 RLN37453.1 - 2.4e-12 45.7 5.2 0.00052 19.7 0.1 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 RLN37453.1 - 1.9e-11 42.9 5.1 6.1e-05 22.3 0.9 3.6 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 RLN37453.1 - 2.2e-11 44.0 5.8 3.8e-09 36.9 1.2 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RLN37453.1 - 8.3e-06 25.6 6.6 0.26 11.1 0.2 3.8 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 RLN37453.1 - 0.0087 16.4 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.9 RLN37453.1 - 0.036 14.4 0.3 0.036 14.4 0.3 2.1 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DAGK_cat PF00781.24 RLN37454.1 - 1.7e-25 89.1 0.1 2.6e-25 88.5 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ephrin_rec_like PF07699.13 RLN37478.1 - 2.7e-05 23.8 54.3 0.0022 17.7 0.5 8.4 6 3 3 9 9 9 7 Putative ephrin-receptor like CIMR PF00878.18 RLN37478.1 - 0.00059 19.9 0.7 0.0014 18.7 0.7 1.7 1 0 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.6 RLN37478.1 - 0.0089 15.7 0.3 0.018 14.7 0.3 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 RLN37478.1 - 0.009 15.9 0.3 0.009 15.9 0.3 2.9 3 0 0 3 3 3 1 Autophagy-related protein 27 FYVE PF01363.21 RLN37480.1 - 7.9e-12 45.2 6.6 2e-11 43.8 6.6 1.7 1 0 0 1 1 1 1 FYVE zinc finger Lin-8 PF03353.15 RLN37480.1 - 7 6.1 17.9 4.1 6.9 1.0 2.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Ank_2 PF12796.7 RLN37485.1 - 3.5e-19 69.2 0.9 1.4e-07 32.0 0.0 4.6 3 2 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN37485.1 - 8.4e-17 61.3 10.3 8.5e-07 29.4 0.2 7.2 5 3 1 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN37485.1 - 1.1e-13 51.0 8.0 0.018 15.4 0.1 6.7 3 1 4 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN37485.1 - 5.1e-06 26.4 11.4 8.9 7.3 0.1 8.1 9 1 1 10 10 10 2 Ankyrin repeat DUF5049 PF16468.5 RLN37485.1 - 0.00057 19.7 0.3 9.2 6.2 0.0 4.3 3 1 2 5 5 5 2 Domain of unknown function (DUF5049) Sushi_2 PF09014.10 RLN37485.1 - 0.2 11.6 1.1 19 5.2 0.0 3.1 2 1 2 4 4 4 0 Beta-2-glycoprotein-1 fifth domain ABA_GPCR PF12430.8 RLN37486.1 - 2.3e-23 82.9 7.1 2.3e-23 82.9 7.1 2.3 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 RLN37486.1 - 6.3e-20 71.0 0.0 2.1e-19 69.3 0.0 1.9 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal WD40 PF00400.32 RLN37487.1 - 3.2e-06 27.8 10.3 0.0029 18.4 0.3 5.7 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN37487.1 - 0.005 17.1 0.9 1.9 8.8 0.0 3.8 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Guanylate_cyc PF00211.20 RLN37488.1 - 2.5e-92 307.5 4.5 1.7e-52 177.7 0.4 3.5 3 0 0 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain PhoLip_ATPase_C PF16212.5 RLN37488.1 - 6.7e-65 219.3 19.5 6.7e-65 219.3 19.5 3.8 4 1 0 4 4 4 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RLN37488.1 - 3.5e-23 81.1 2.9 8.5e-23 79.8 2.9 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RLN37488.1 - 1.3e-09 38.7 1.0 1.2e-05 25.7 0.5 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN37488.1 - 1.9e-05 24.6 0.0 0.00012 22.1 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RLN37488.1 - 0.00025 20.6 0.0 0.0016 18.0 0.0 2.3 1 1 0 1 1 1 1 E1-E2 ATPase HNOBA PF07701.14 RLN37488.1 - 0.039 13.4 1.6 2.2 7.7 0.1 2.4 2 0 0 2 2 2 0 Heme NO binding associated Hydrolase_3 PF08282.12 RLN37488.1 - 0.18 11.5 0.1 0.46 10.2 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ank_2 PF12796.7 RLN37489.1 - 5e-11 43.0 0.0 2.2e-05 25.0 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN37489.1 - 8.3e-09 35.8 2.6 0.0087 16.6 0.1 4.6 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN37489.1 - 3e-07 30.6 0.8 0.42 11.0 0.0 4.7 3 1 2 5 5 5 3 Ankyrin repeats (many copies) DUF5049 PF16468.5 RLN37489.1 - 0.0033 17.3 0.1 2.9 7.8 0.0 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF5049) Glyco_trans_1_2 PF13524.6 RLN37489.1 - 0.049 14.0 0.1 0.69 10.3 0.0 2.6 2 1 1 3 3 3 0 Glycosyl transferases group 1 Ank_4 PF13637.6 RLN37490.1 - 8e-06 26.3 0.2 0.087 13.4 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN37490.1 - 0.00072 20.1 0.0 0.84 10.3 0.1 2.9 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) HTH_20 PF12840.7 RLN37490.1 - 0.074 13.1 0.1 15 5.7 0.0 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain Ank_5 PF13857.6 RLN37490.1 - 0.1 12.9 0.0 6.9 7.1 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN37490.1 - 0.2 12.3 0.4 1.2e+02 3.7 0.0 4.5 6 0 0 6 6 6 0 Ankyrin repeat Fibrillarin PF01269.17 RLN37527.1 - 1.6e-27 96.1 0.1 8.3e-16 57.8 0.0 2.0 1 1 1 2 2 2 2 Fibrillarin FAM70 PF14967.6 RLN37527.1 - 0.082 12.4 0.0 0.084 12.3 0.0 1.0 1 0 0 1 1 1 0 FAM70 protein DUF563 PF04577.14 RLN37529.1 - 2.5e-31 109.5 0.0 4e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) HTH_21 PF13276.6 RLN37529.1 - 0.41 10.8 3.5 4.4 7.5 0.1 2.6 2 1 0 2 2 2 0 HTH-like domain CtsR_C PF17727.1 RLN37531.1 - 0.031 14.4 0.2 11 6.2 0.1 2.8 2 0 0 2 2 2 0 CtsR C-terminal dimerization domain SGT1 PF07093.11 RLN37531.1 - 0.13 10.7 4.1 0.23 9.8 4.1 1.3 1 0 0 1 1 1 0 SGT1 protein DUF848 PF05852.11 RLN37531.1 - 1.2 9.3 6.6 2.1 8.5 1.1 2.9 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) FYVE PF01363.21 RLN37533.1 - 1.3e-12 47.6 10.0 3.2e-12 46.4 10.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN37533.1 - 0.011 15.9 11.0 0.026 14.8 11.0 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger Integrase_H2C2 PF17921.1 RLN37533.1 - 0.05 13.7 0.1 0.05 13.7 0.1 2.3 2 0 0 2 2 2 0 Integrase zinc binding domain zf-B_box PF00643.24 RLN37533.1 - 2.7 8.2 8.5 1.3 9.3 5.3 2.1 2 0 0 2 2 2 0 B-box zinc finger FYVE PF01363.21 RLN37534.1 - 4.6e-11 42.7 14.1 1.2e-10 41.4 14.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger Pkinase PF00069.25 RLN37535.1 - 1.6e-48 165.3 0.0 1.2e-41 142.9 0.0 3.9 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN37535.1 - 1.3e-45 155.8 0.0 1.7e-40 139.0 0.0 3.7 3 1 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.22 RLN37535.1 - 0.0031 17.1 0.0 0.0073 15.9 0.0 1.5 1 0 0 1 1 1 1 RIO1 family DUF5129 PF17173.4 RLN37535.1 - 0.0043 16.2 2.2 0.007 15.5 2.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5129) Kinase-like PF14531.6 RLN37535.1 - 0.023 14.0 0.0 0.091 12.1 0.0 2.0 1 1 0 1 1 1 0 Kinase-like Tugs PF17840.1 RLN37535.1 - 0.041 14.1 0.6 2.2 8.5 0.1 3.4 3 0 0 3 3 3 0 Tethering Ubl4a to BAGS domain Kdo PF06293.14 RLN37535.1 - 0.073 12.4 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4606 PF15379.6 RLN37535.1 - 0.1 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) Cid2 PF09774.9 RLN37535.1 - 0.13 12.7 0.2 0.13 12.7 0.2 1.8 2 0 0 2 2 2 0 Caffeine-induced death protein 2 SDF PF00375.18 RLN37540.1 - 6.4e-69 232.8 33.5 2.3e-68 231.0 33.5 1.8 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family Choline_transpo PF04515.12 RLN37541.1 - 7e-72 242.4 38.2 7e-72 242.4 38.2 2.3 1 1 0 2 2 2 1 Plasma-membrane choline transporter DUF677 PF05055.12 RLN37541.1 - 0.5 9.2 2.6 24 3.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF677) Helicase_C_2 PF13307.6 RLN37542.1 - 2.3e-55 187.4 0.0 7.6e-55 185.7 0.0 2.0 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 RLN37542.1 - 1.7e-50 171.1 1.1 3.2e-50 170.2 1.1 1.5 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 RLN37542.1 - 5.4e-05 23.0 0.1 0.016 15.0 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 RLN37542.1 - 0.00022 21.3 2.5 0.017 15.1 0.3 3.6 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit PhoH PF02562.16 RLN37542.1 - 0.15 11.5 0.1 8.3 5.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein SNF2_N PF00176.23 RLN37542.1 - 0.21 10.3 1.1 0.57 8.8 1.1 1.9 1 1 0 1 1 1 0 SNF2 family N-terminal domain STAG PF08514.11 RLN37542.1 - 1.8 8.5 4.5 1.4 8.9 1.4 2.3 2 0 0 2 2 2 0 STAG domain Pkinase PF00069.25 RLN37544.1 - 2.7e-43 148.3 0.0 3.2e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN37544.1 - 6e-26 91.3 0.0 9.2e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN37544.1 - 0.00014 21.2 0.0 0.00021 20.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RLN37544.1 - 0.004 16.1 0.0 0.006 15.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 RLN37544.1 - 0.032 13.9 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 RLN37544.1 - 0.035 12.9 0.2 0.058 12.2 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 RLN37544.1 - 0.083 12.8 0.4 0.083 12.8 0.4 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family ThiF PF00899.21 RLN37545.1 - 7e-12 45.2 0.0 9.3e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family LRR_9 PF14580.6 RLN37546.1 - 4.1e-07 29.7 0.0 4.7e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 RLN37546.1 - 0.0013 19.1 0.2 0.23 12.0 0.0 1.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RLN37546.1 - 0.05 13.7 0.2 0.79 9.9 0.0 2.4 2 0 0 2 2 2 0 Leucine Rich repeat Ras PF00071.22 RLN37547.1 - 2.2e-27 95.6 0.0 3.6e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN37547.1 - 1.5e-21 76.8 0.0 2.3e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN37547.1 - 5.4e-09 35.7 0.0 8.5e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RLN37547.1 - 7.6e-08 32.4 0.0 6.8e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RLN37547.1 - 0.0035 16.9 0.1 0.0058 16.2 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RLN37547.1 - 0.0084 16.0 0.0 0.069 13.0 0.0 2.1 2 1 0 2 2 2 1 RsgA GTPase cobW PF02492.19 RLN37547.1 - 0.11 12.1 0.0 7 6.2 0.0 2.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 RLN37547.1 - 0.13 12.7 0.1 0.39 11.2 0.0 1.8 2 0 0 2 2 2 0 ABC transporter Condensin2nSMC PF12422.8 RLN37548.1 - 4.5e-24 85.3 0.7 1.8e-13 50.9 0.0 3.5 2 1 1 3 3 3 2 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 RLN37548.1 - 4.2e-06 26.6 0.5 5.7 7.5 0.0 5.4 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 RLN37548.1 - 0.00015 22.1 0.0 0.41 11.1 0.0 3.9 1 1 1 2 2 2 2 HEAT repeats Vac14_Fab1_bd PF12755.7 RLN37548.1 - 0.098 13.3 0.1 2.7 8.7 0.0 3.5 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region FAM176 PF14851.6 RLN37548.1 - 2 8.0 7.9 0.12 12.1 1.8 2.0 3 0 0 3 3 3 0 FAM176 family Sarcolipin PF05366.11 RLN37548.1 - 6.3 6.6 5.9 18 5.2 0.2 2.7 3 0 0 3 3 3 0 Sarcolipin Cpn60_TCP1 PF00118.24 RLN37549.1 - 2.4e-155 517.9 13.3 2.8e-155 517.7 13.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 RLN37549.1 - 0.0098 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination S-methyl_trans PF02574.16 RLN37549.1 - 0.011 15.6 0.1 0.023 14.5 0.1 1.5 1 0 0 1 1 1 0 Homocysteine S-methyltransferase SlyX PF04102.12 RLN37550.1 - 0.055 14.1 1.0 0.32 11.6 0.3 2.1 2 0 0 2 2 2 0 SlyX PEARLI-4 PF05278.12 RLN37550.1 - 0.15 11.7 0.1 0.22 11.1 0.1 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF3138 PF11336.8 RLN37550.1 - 1.1 7.8 4.5 1.9 7.0 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SMC_N PF02463.19 RLN37553.1 - 1.7e-24 86.5 10.1 1.7e-24 86.5 10.1 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 RLN37553.1 - 3.3e-24 85.4 1.2 3.7e-23 82.1 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 RLN37553.1 - 1.8e-11 44.4 15.4 1.8e-11 44.4 15.4 2.9 2 1 0 2 2 1 1 AAA ATPase domain AAA_23 PF13476.6 RLN37553.1 - 3.3e-07 31.0 30.7 3.3e-07 31.0 30.7 6.4 2 2 3 5 5 1 1 AAA domain AAA_21 PF13304.6 RLN37553.1 - 4.9e-06 26.6 0.0 4.9e-06 26.6 0.0 2.6 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN37553.1 - 2.6e-05 23.9 0.0 5.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 RLN37553.1 - 0.00098 18.1 14.7 0.00098 18.1 14.7 6.7 2 2 4 6 6 6 2 Spc7 kinetochore protein FPP PF05911.11 RLN37553.1 - 0.0016 16.8 13.5 0.0016 16.8 13.5 5.0 2 2 3 5 5 5 3 Filament-like plant protein, long coiled-coil DUF3450 PF11932.8 RLN37553.1 - 0.0036 16.6 3.7 0.0036 16.6 3.7 6.9 3 2 5 8 8 8 1 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.8 RLN37553.1 - 0.0069 16.6 5.9 0.0069 16.6 5.9 8.7 3 2 4 8 8 6 2 TATA element modulatory factor 1 TATA binding DUF4140 PF13600.6 RLN37553.1 - 0.0078 16.6 0.3 0.0078 16.6 0.3 9.4 4 3 2 7 7 4 1 N-terminal domain of unknown function (DUF4140) Baculo_PEP_C PF04513.12 RLN37553.1 - 2.1 8.4 24.3 0.13 12.3 1.5 4.3 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Myb_DNA-binding PF00249.31 RLN37558.1 - 4.9e-35 119.5 9.4 6.1e-14 51.9 0.1 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN37558.1 - 9.9e-24 83.4 5.1 9.3e-13 48.2 0.2 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain LRR_8 PF13855.6 RLN37558.1 - 0.015 15.0 1.5 0.03 14.1 0.4 2.1 2 0 0 2 2 2 0 Leucine rich repeat MADF_DNA_bdg PF10545.9 RLN37558.1 - 0.023 15.0 4.7 0.41 11.0 0.3 3.6 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like LRR_4 PF12799.7 RLN37558.1 - 0.029 14.8 2.1 2 8.9 0.1 3.4 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) SLIDE PF09111.10 RLN37558.1 - 0.06 13.4 0.0 11 6.0 0.0 2.8 1 1 2 3 3 3 0 SLIDE Ank_2 PF12796.7 RLN37559.1 - 1.4e-24 86.4 1.5 2.5e-11 44.0 0.1 3.7 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN37559.1 - 4e-14 52.8 0.3 2.5e-11 43.9 0.2 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN37559.1 - 4.3e-13 48.2 0.6 0.0016 18.7 0.0 4.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 RLN37559.1 - 2.6e-12 46.7 2.5 2e-05 24.8 0.8 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN37559.1 - 7.2e-12 45.2 2.9 5.2e-05 23.5 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat FYVE PF01363.21 RLN37559.1 - 5.1e-06 26.5 6.5 1e-05 25.5 6.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger DZR PF12773.7 RLN37559.1 - 3.1 7.9 10.1 26 5.0 0.0 2.5 2 0 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 RLN37559.1 - 4.4 7.4 11.7 3.7 7.6 6.8 2.3 2 0 0 2 2 2 0 zinc-ribbons DUF3886 PF13025.6 RLN37559.1 - 8.3 6.7 16.3 8.1 6.7 14.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) zf-U1 PF06220.12 RLN37560.1 - 0.00059 19.6 2.1 0.00075 19.2 0.5 2.1 2 0 0 2 2 2 1 U1 zinc finger Drf_FH1 PF06346.12 RLN37560.1 - 0.0022 17.7 19.9 0.0039 16.9 19.9 1.3 1 0 0 1 1 1 1 Formin Homology Region 1 PRKCSH-like PF12999.7 RLN37560.1 - 1.5 8.6 3.6 2.8 7.7 3.6 1.4 1 0 0 1 1 1 0 Glucosidase II beta subunit-like Tombus_movement PF05318.12 RLN37560.1 - 9.2 7.2 7.1 0.72 10.7 0.7 2.3 2 0 0 2 2 2 0 Tombusvirus movement protein Hexapep PF00132.24 RLN37561.1 - 1.1e-16 59.7 12.1 2.8e-06 26.8 0.3 4.3 4 0 0 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 RLN37561.1 - 0.00047 19.8 15.7 0.0014 18.4 0.5 4.0 4 1 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 RLN37561.1 - 0.067 12.1 0.2 0.12 11.3 0.2 1.4 1 1 0 1 1 1 0 L-fucokinase EF-hand_1 PF00036.32 RLN37562.1 - 1.6e-13 49.1 0.9 1.1e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RLN37562.1 - 5.1e-13 48.7 0.6 2.2e-10 40.2 0.1 1.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 RLN37562.1 - 8.5e-13 48.6 0.5 3.4e-12 46.6 0.5 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN37562.1 - 4e-11 41.9 0.9 5.8e-06 25.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RLN37562.1 - 8e-11 40.9 1.9 1e-05 24.8 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_11 PF08976.11 RLN37562.1 - 8.5e-06 26.6 0.2 9.6e-06 26.4 0.2 1.1 1 0 0 1 1 1 1 EF-hand domain Caleosin PF05042.13 RLN37562.1 - 0.003 17.5 0.2 0.042 13.8 0.0 2.0 2 0 0 2 2 2 1 Caleosin related protein EF-hand_4 PF12763.7 RLN37562.1 - 0.0087 16.0 0.2 0.011 15.7 0.2 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DUF5580 PF17743.1 RLN37562.1 - 0.039 12.5 0.0 0.044 12.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) PH PF00169.29 RLN37563.1 - 0.0091 16.5 0.0 3.3 8.3 0.0 2.3 2 0 0 2 2 2 2 PH domain TMEM208_SND2 PF05620.11 RLN37564.1 - 2.6e-18 66.4 2.2 1e-15 57.9 0.0 2.0 1 1 1 2 2 2 2 SRP-independent targeting protein 2/TMEM208 MIOX PF05153.15 RLN37564.1 - 0.071 12.7 0.2 0.099 12.2 0.2 1.2 1 0 0 1 1 1 0 Myo-inositol oxygenase Myb_DNA-binding PF00249.31 RLN37565.1 - 0.034 14.3 0.0 0.073 13.3 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain PX PF00787.24 RLN37566.1 - 1.7e-12 47.4 0.0 2.1e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 PX domain Glyco_hydro_5_C PF18564.1 RLN37567.1 - 8.2e-18 64.7 0.0 1.5e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 RLN37567.1 - 6.6e-12 45.4 0.0 1.8e-09 37.5 0.0 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Sec16_C PF12931.7 RLN37569.1 - 7e-41 140.8 0.4 3.6e-30 105.6 0.0 2.2 1 1 1 2 2 2 2 Sec23-binding domain of Sec16 Sec16 PF12932.7 RLN37569.1 - 2.3e-13 50.8 0.1 1.5e-12 48.2 0.0 2.5 3 0 0 3 3 3 1 Vesicle coat trafficking protein Sec16 mid-region RabGAP-TBC PF00566.18 RLN37569.1 - 0.016 14.9 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Ras PF00071.22 RLN37571.1 - 4.8e-24 84.8 0.0 9.3e-13 48.1 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 RLN37571.1 - 5.7e-07 29.8 0.0 3.6e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 RLN37571.1 - 7.7e-05 22.7 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase End_beta_barrel PF12195.8 RLN37571.1 - 0.029 14.3 0.2 0.052 13.5 0.2 1.4 1 0 0 1 1 1 0 Beta barrel domain of bacteriophage endosialidase AAA_16 PF13191.6 RLN37571.1 - 0.057 13.8 0.0 0.087 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Ribosomal_L14 PF00238.19 RLN37572.1 - 6.2e-36 123.2 0.0 7.4e-36 122.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Myosin_head PF00063.21 RLN37573.1 - 5.8e-228 758.5 0.0 7.2e-228 758.2 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 RLN37573.1 - 1.5e-17 61.6 22.0 3.1e-06 26.5 0.3 4.9 4 0 0 4 4 4 4 IQ calmodulin-binding motif PDZ_6 PF17820.1 RLN37573.1 - 6.6e-06 25.9 0.0 0.27 11.1 0.0 3.5 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 RLN37573.1 - 0.00028 21.2 0.1 0.01 16.2 0.0 3.1 3 0 0 3 3 3 1 PDZ domain Sigma54_activat PF00158.26 RLN37573.1 - 0.0015 18.3 0.0 0.0036 17.0 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain PDZ_2 PF13180.6 RLN37573.1 - 0.0036 17.6 0.0 0.49 10.8 0.0 2.6 2 0 0 2 2 2 1 PDZ domain AAA_16 PF13191.6 RLN37573.1 - 0.01 16.2 0.1 0.28 11.5 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 RLN37573.1 - 0.12 12.7 0.0 0.43 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RLN37573.1 - 0.22 10.8 2.0 0.23 10.7 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Thioredoxin_8 PF13905.6 RLN37574.1 - 1.9e-26 92.2 0.0 2.5e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 RLN37574.1 - 9.8e-10 38.3 0.0 1.2e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 RLN37574.1 - 1.4e-09 37.9 0.0 0.00016 21.6 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin AhpC-TSA PF00578.21 RLN37574.1 - 7.3e-09 35.6 0.0 9.1e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 RLN37574.1 - 3.5e-08 33.9 0.0 5.2e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 RLN37574.1 - 0.022 14.5 0.0 1.1 9.0 0.0 2.2 1 1 0 1 1 1 0 Thioredoxin Glutaredoxin PF00462.24 RLN37574.1 - 0.034 14.4 0.1 0.31 11.3 0.1 2.2 1 1 0 1 1 1 0 Glutaredoxin DUF2922 PF11148.8 RLN37574.1 - 0.043 13.5 0.0 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) UL11 PF11094.8 RLN37574.1 - 0.054 13.4 2.3 0.2 11.5 0.0 2.5 3 0 0 3 3 3 0 Membrane-associated tegument protein OST3_OST6 PF04756.13 RLN37574.1 - 0.075 12.4 0.0 0.83 8.9 0.0 2.0 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family RBFA PF02033.18 RLN37574.1 - 0.091 13.2 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 Ribosome-binding factor A PH PF00169.29 RLN37575.1 - 3.1e-09 37.3 0.3 1e-08 35.6 0.3 1.8 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN37575.1 - 6.4e-05 23.3 1.0 0.00025 21.4 1.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 RLN37575.1 - 0.015 15.5 0.1 0.024 14.9 0.1 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain zf-MYND PF01753.18 RLN37576.1 - 6.2e-07 29.4 11.6 6.2e-07 29.4 11.6 1.6 2 0 0 2 2 2 1 MYND finger Pico_P2A PF00947.19 RLN37576.1 - 0.073 13.1 0.8 0.12 12.4 0.8 1.3 1 0 0 1 1 1 0 Picornavirus core protein 2A zf-Mss51 PF13824.6 RLN37576.1 - 2.1 8.5 8.2 9.4 6.4 8.2 2.0 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 GRP PF07172.11 RLN37577.1 - 7.3 7.3 24.0 19 6.0 24.0 1.7 1 1 0 1 1 1 0 Glycine rich protein family Lig_chan PF00060.26 RLN37579.1 - 0.023 14.5 0.1 58 3.5 0.0 3.8 4 0 0 4 4 4 0 Ligand-gated ion channel PMP1_2 PF08114.11 RLN37579.1 - 0.65 9.8 16.6 15 5.4 0.4 4.4 4 0 0 4 4 4 0 ATPase proteolipid family DUF555 PF04475.12 RLN37579.1 - 0.8 10.1 3.2 71 3.8 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF555) Gag_MA PF01140.19 RLN37580.1 - 0.095 12.4 1.9 45 3.8 0.1 3.2 3 0 0 3 3 3 0 Matrix protein (MA), p15 Lustrin_cystein PF14625.6 RLN37580.1 - 0.23 11.9 22.1 7.3 7.1 0.4 5.7 4 1 2 6 6 6 0 Lustrin, cysteine-rich repeated domain Dickkopf_N PF04706.12 RLN37580.1 - 3.6 8.1 28.9 1.1 9.8 2.6 5.9 5 2 1 6 6 6 0 Dickkopf N-terminal cysteine-rich region OrfB_Zn_ribbon PF07282.11 RLN37581.1 - 4.4e-06 26.5 7.3 0.0067 16.3 0.9 2.3 1 1 1 2 2 2 2 Putative transposase DNA-binding domain MCR PF18509.1 RLN37581.1 - 0.13 11.9 0.8 1.1 8.9 0.1 2.2 2 0 0 2 2 2 0 Magnetochrome domain RSN1_7TM PF02714.15 RLN37582.1 - 0.00027 20.4 7.9 0.081 12.2 7.6 3.1 1 1 1 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate Anoctamin PF04547.12 RLN37582.1 - 0.001 18.0 3.7 0.001 18.0 3.7 2.4 2 2 0 2 2 2 1 Calcium-activated chloride channel PalH PF08733.10 RLN37582.1 - 0.0074 15.3 1.9 0.0074 15.3 1.9 1.9 2 0 0 2 2 2 1 PalH/RIM21 AATase PF07247.12 RLN37583.1 - 0.2 10.2 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Alcohol acetyltransferase ubiquitin PF00240.23 RLN37584.1 - 1e-11 44.4 0.0 1.4e-11 44.0 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 RLN37584.1 - 0.00015 22.3 0.0 0.00017 22.1 0.0 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 RLN37584.1 - 0.005 16.9 0.0 0.0061 16.6 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 RLN37584.1 - 0.14 12.0 0.0 0.18 11.7 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_S13_N PF08069.12 RLN37587.1 - 0.087 12.9 0.0 25 5.0 0.0 2.8 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain DUF1965 PF09248.10 RLN37587.1 - 0.1 12.4 2.3 3 7.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1965) Nudix_N PF12535.8 RLN37587.1 - 0.12 12.0 0.9 22 4.7 0.1 3.0 2 0 0 2 2 2 0 Hydrolase of X-linked nucleoside diphosphate N terminal BAT2_N PF07001.11 RLN37588.1 - 0.7 10.3 18.5 1.5 9.3 18.5 1.5 1 0 0 1 1 1 0 BAT2 N-terminus FYVE PF01363.21 RLN37594.1 - 0.00016 21.8 11.7 0.00016 21.8 11.7 1.9 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 RLN37594.1 - 0.005 17.0 14.3 0.0078 16.4 7.0 2.7 1 1 1 2 2 2 2 FYVE-type zinc finger C1_2 PF03107.16 RLN37594.1 - 0.44 10.9 6.4 1.5 9.2 4.3 2.6 2 0 0 2 2 2 0 C1 domain Abhydrolase_1 PF00561.20 RLN37611.1 - 1.2e-18 67.7 0.0 3.4e-13 49.8 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN37611.1 - 1.5e-08 35.5 2.2 1.1e-07 32.7 2.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN37611.1 - 1.9e-06 27.3 0.0 0.00094 18.5 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 RLN37611.1 - 0.003 17.2 0.0 0.012 15.2 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Ndr PF03096.14 RLN37611.1 - 0.0053 15.5 0.0 0.0092 14.7 0.0 1.3 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.11 RLN37611.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DDHD PF02862.17 RLN37612.1 - 6.3e-28 98.5 0.5 1.3e-27 97.4 0.0 1.6 2 0 0 2 2 2 1 DDHD domain zf-TRAF PF02176.18 RLN37613.1 - 5.9e-17 62.1 59.7 1.1e-05 26.0 4.1 6.8 6 0 0 6 6 6 5 TRAF-type zinc finger Laminin_G_3 PF13385.6 RLN37613.1 - 9.3e-10 38.8 0.0 1.7e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily zf-RING_7 PF02591.15 RLN37613.1 - 0.044 14.0 0.1 0.33 11.2 0.1 2.7 1 0 0 1 1 1 0 C4-type zinc ribbon domain DFRP_C PF16543.5 RLN37613.1 - 6.4 7.3 7.5 11 6.5 1.9 3.3 3 0 0 3 3 3 0 DRG Family Regulatory Proteins, Tma46 HTH_38 PF13936.6 RLN37615.1 - 2.5e-08 33.6 1.2 3.5e-08 33.1 0.2 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 RLN37615.1 - 2.5e-06 27.2 0.0 4.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Tc3 transposase HTH_32 PF13565.6 RLN37615.1 - 0.0053 17.3 4.3 0.35 11.5 0.5 2.6 1 1 1 2 2 2 2 Homeodomain-like domain HTH_23 PF13384.6 RLN37615.1 - 0.0082 15.9 1.8 0.059 13.2 0.1 2.6 2 1 0 2 2 2 1 Homeodomain-like domain PDDEXK_1 PF12705.7 RLN37616.1 - 5.1e-25 88.8 0.1 1.5e-24 87.3 0.0 1.9 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Dna2 PF08696.11 RLN37616.1 - 0.011 15.6 0.5 0.08 12.7 0.0 2.2 2 0 0 2 2 2 0 DNA replication factor Dna2 ATP19 PF11022.8 RLN37616.1 - 0.025 14.9 0.2 0.11 12.9 0.2 2.1 1 0 0 1 1 1 0 ATP synthase subunit K Csa1 PF06023.12 RLN37616.1 - 0.12 11.8 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 CHASE8 PF17152.4 RLN37616.1 - 0.71 10.1 4.6 0.76 10.1 0.3 2.9 3 0 0 3 3 3 0 Periplasmic sensor domain Coilin_N PF15862.5 RLN37617.1 - 3.6e-18 65.7 0.0 6.8e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Coilin N-terminus IMUP PF15761.5 RLN37617.1 - 7.7 7.3 17.5 1.3 9.8 12.0 2.4 1 1 1 2 2 2 0 Immortalisation up-regulated protein PEPCK_ATP PF01293.20 RLN37618.1 - 7.8e-09 34.7 0.0 9.5e-09 34.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase MHYT PF03707.16 RLN37640.1 - 1.8e-14 53.7 11.6 1.8e-13 50.4 0.2 2.7 2 1 0 2 2 2 2 Bacterial signalling protein N terminal repeat MHYT PF03707.16 RLN37641.1 - 3e-43 145.8 60.3 6.4e-13 48.7 0.3 7.4 6 2 0 6 6 6 6 Bacterial signalling protein N terminal repeat LPAM_2 PF13627.6 RLN37641.1 - 0.68 9.9 15.6 2.1 8.3 2.3 3.7 2 0 0 2 2 2 0 Prokaryotic lipoprotein-attachment site Glucokinase PF02685.16 RLN37643.1 - 2.1e-82 276.7 0.0 2.4e-82 276.5 0.0 1.0 1 0 0 1 1 1 1 Glucokinase Glucokinase PF02685.16 RLN37644.1 - 1.4e-144 480.9 0.0 7.6e-75 251.8 0.0 3.3 2 1 1 3 3 3 3 Glucokinase Gly-zipper_YMGG PF13441.6 RLN37644.1 - 0.88 9.4 10.1 0.3 10.8 1.8 3.3 3 0 0 3 3 3 0 YMGG-like Gly-zipper MHYT PF03707.16 RLN37645.1 - 6.2e-15 55.1 12.3 1.8e-13 50.4 0.2 2.7 2 1 0 2 2 2 2 Bacterial signalling protein N terminal repeat IPTL-CTERM PF18203.1 RLN37645.1 - 4.9 7.1 5.8 0.94 9.5 0.5 2.5 2 0 0 2 2 2 0 IPTL-CTERM motif SAPS PF04499.15 RLN37647.1 - 0.13 11.0 1.2 0.13 11.1 1.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Smg8_Smg9 PF10220.9 RLN37647.1 - 4.3 5.5 5.4 5 5.3 5.4 1.1 1 0 0 1 1 1 0 Smg8_Smg9 SSP160 PF06933.11 RLN37648.1 - 0.051 11.8 6.5 0.069 11.4 6.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PA14 PF07691.12 RLN37648.1 - 0.053 13.3 0.3 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 PA14 domain PA14 PF07691.12 RLN37649.1 - 0.015 15.1 0.8 0.1 12.4 0.0 2.4 2 1 0 2 2 2 0 PA14 domain FAM70 PF14967.6 RLN37649.1 - 0.24 10.8 4.1 0.36 10.3 4.1 1.3 1 0 0 1 1 1 0 FAM70 protein 7tm_3 PF00003.22 RLN37650.1 - 1e-40 140.0 23.2 1e-40 140.0 23.2 1.8 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR HIG_1_N PF04588.13 RLN37650.1 - 0.00029 21.0 0.4 0.00029 21.0 0.4 2.7 2 0 0 2 2 2 1 Hypoxia induced protein conserved region ENOD93 PF03386.14 RLN37650.1 - 0.036 13.9 3.4 0.026 14.4 1.0 2.1 2 0 0 2 2 2 0 Early nodulin 93 ENOD93 protein Abhydrolase_6 PF12697.7 RLN37651.1 - 0.016 15.8 0.1 0.018 15.7 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family PP2C PF00481.21 RLN37654.1 - 1.4e-11 44.6 0.0 0.0085 15.7 0.0 3.5 3 1 0 3 3 3 3 Protein phosphatase 2C PP2C_2 PF13672.6 RLN37654.1 - 7.8e-05 22.4 0.4 0.00053 19.7 0.1 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C tRNA-synt_2d PF01409.20 RLN37655.1 - 1e-50 172.5 0.4 2.2e-50 171.5 0.4 1.5 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 RLN37655.1 - 4.7e-20 71.8 0.4 1.3e-19 70.4 0.1 1.9 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.20 RLN37655.1 - 0.026 13.6 0.2 3.8 6.5 0.1 2.3 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) UPF0029 PF01205.19 RLN37656.1 - 2.3e-27 95.4 0.0 3.8e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF1949 PF09186.11 RLN37656.1 - 8.9e-06 25.5 0.0 1.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1949) DENN PF02141.21 RLN37657.1 - 2.2e-25 89.7 2.5 4.1e-25 88.8 0.7 2.3 2 1 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.19 RLN37657.1 - 0.094 12.7 0.2 0.26 11.3 0.2 1.7 1 0 0 1 1 1 0 dDENN domain NOA36 PF06524.12 RLN37657.1 - 0.31 10.3 5.2 0.57 9.5 5.2 1.3 1 0 0 1 1 1 0 NOA36 protein DUF4611 PF15387.6 RLN37657.1 - 0.71 10.1 7.8 2.2 8.6 7.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 RLN37657.1 - 7.8 4.5 11.2 11 3.9 11.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Lung_7-TM_R PF06814.13 RLN37658.1 - 1.4e-42 146.0 10.0 1.6e-42 145.8 10.0 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 RLN37658.1 - 0.068 12.6 9.8 0.12 11.8 9.8 1.4 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 RLN37660.1 - 1.2e-16 60.8 1.5 1.6e-16 60.4 1.5 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor TssN PF17555.2 RLN37660.1 - 0.6 9.4 3.3 1.2 8.5 0.0 2.1 1 1 1 2 2 2 0 Type VI secretion system, TssN U1snRNP70_N PF12220.8 RLN37662.1 - 1.6 9.4 14.3 1.4 9.6 4.8 3.1 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal U79_P34 PF03064.16 RLN37662.1 - 9.5 5.5 10.9 4.8 6.5 5.3 2.2 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Cluap1 PF10234.9 RLN37663.1 - 2.2e-97 325.7 16.6 3.2e-97 325.1 16.6 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 Lebercilin PF15619.6 RLN37663.1 - 0.0073 16.0 21.7 0.019 14.6 21.7 1.7 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease tRNA-synt_1b PF00579.25 RLN37663.1 - 0.055 12.8 1.0 0.11 11.8 0.4 1.6 1 1 0 1 1 1 0 tRNA synthetases class I (W and Y) Ndc80_HEC PF03801.13 RLN37663.1 - 0.066 12.8 0.1 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 HEC/Ndc80p family PAD PF03068.15 RLN37663.1 - 0.088 11.8 1.6 0.14 11.1 1.6 1.2 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) Prominin PF05478.11 RLN37663.1 - 0.19 9.6 3.6 0.28 9.1 3.6 1.3 1 0 0 1 1 1 0 Prominin GILT PF03227.16 RLN37664.1 - 9.4e-07 29.1 0.6 2.5e-06 27.7 0.3 1.9 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) CRAL_TRIO PF00650.20 RLN37665.1 - 6.4e-10 39.0 0.0 9.6e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 RLN37665.1 - 0.00026 21.1 0.0 0.00049 20.2 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SDA1 PF05285.12 RLN37665.1 - 0.15 11.5 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 SDA1 DSPc PF00782.20 RLN37666.1 - 0.00019 21.2 0.1 0.00027 20.8 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain C2 PF00168.30 RLN37667.1 - 9e-12 45.2 0.2 2.5e-11 43.8 0.1 1.8 2 0 0 2 2 2 1 C2 domain Arb2 PF09757.9 RLN37667.1 - 0.00029 20.1 0.0 0.00044 19.5 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain FYVE PF01363.21 RLN37667.1 - 0.00084 19.4 6.4 0.0017 18.4 6.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger RCC1 PF00415.18 RLN37668.1 - 9.9e-60 199.0 9.6 1.1e-10 41.9 0.1 7.9 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN37668.1 - 6.8e-24 83.1 27.8 1.9e-09 37.0 0.5 8.2 8 0 0 8 8 8 3 Regulator of chromosome condensation (RCC1) repeat PA PF02225.22 RLN37668.1 - 4e-07 30.0 0.0 0.058 13.4 0.0 3.4 4 0 0 4 4 4 2 PA domain EF-hand_6 PF13405.6 RLN37668.1 - 0.00021 20.9 0.1 0.0014 18.4 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain IQ PF00612.27 RLN37668.1 - 0.0027 17.4 0.0 0.009 15.7 0.0 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif EF-hand_7 PF13499.6 RLN37668.1 - 0.0079 16.6 0.0 0.25 11.8 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN37668.1 - 0.014 14.9 0.3 0.04 13.5 0.3 1.8 1 0 0 1 1 1 0 EF hand SYCE1 PF15233.6 RLN37668.1 - 0.018 15.1 3.0 0.029 14.5 3.0 1.2 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 Sharpin_PH PF16764.5 RLN37668.1 - 0.034 13.9 0.1 0.57 9.9 0.0 2.3 2 0 0 2 2 2 0 Sharpin PH domain EF-hand_8 PF13833.6 RLN37668.1 - 0.19 11.6 0.1 0.39 10.6 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair DSPc PF00782.20 RLN37669.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Ribosomal_S24e PF01282.19 RLN37670.1 - 1.3e-28 98.7 0.7 2e-28 98.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S24e ABC_tran PF00005.27 RLN37671.1 - 1.2e-44 152.2 0.0 8e-24 84.7 0.0 4.3 4 1 0 4 4 3 2 ABC transporter AAA_21 PF13304.6 RLN37671.1 - 8.3e-14 52.1 11.1 0.012 15.4 0.0 5.8 5 1 0 6 6 6 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 RLN37671.1 - 1.3e-07 31.5 7.9 1.3e-07 31.5 7.9 5.7 5 1 0 5 5 2 1 ABC transporter AAA_29 PF13555.6 RLN37671.1 - 1.8e-07 30.7 1.1 0.0061 16.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 RLN37671.1 - 3.2e-07 30.0 15.7 0.024 14.1 0.0 5.5 4 2 0 5 5 5 3 RecF/RecN/SMC N terminal domain AAA PF00004.29 RLN37671.1 - 4.2e-06 27.2 0.2 0.23 11.9 0.2 3.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN37671.1 - 1.8e-05 25.0 0.0 0.02 15.2 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 RLN37671.1 - 2.7e-05 24.7 2.7 0.0021 18.6 0.2 6.3 4 3 1 5 5 2 2 AAA domain NACHT PF05729.12 RLN37671.1 - 0.00035 20.5 1.9 0.18 11.7 0.1 2.6 2 0 0 2 2 2 2 NACHT domain AAA_24 PF13479.6 RLN37671.1 - 0.00035 20.4 5.8 0.14 11.9 0.1 4.0 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 RLN37671.1 - 0.00054 20.1 1.9 0.33 11.1 0.0 3.8 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 RLN37671.1 - 0.00084 19.3 5.8 0.0033 17.3 0.0 2.9 3 0 0 3 3 2 1 RsgA GTPase NTPase_1 PF03266.15 RLN37671.1 - 0.0012 18.8 0.1 0.5 10.3 0.1 3.0 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.22 RLN37671.1 - 0.0014 19.0 0.9 0.63 10.5 0.0 3.2 3 0 0 3 3 2 1 RNA helicase AAA_16 PF13191.6 RLN37671.1 - 0.0034 17.8 9.9 0.11 12.9 0.0 3.7 3 1 0 3 3 2 2 AAA ATPase domain AAA_28 PF13521.6 RLN37671.1 - 0.0036 17.6 2.6 0.88 9.8 0.0 3.8 4 0 0 4 4 2 1 AAA domain AAA_14 PF13173.6 RLN37671.1 - 0.0052 16.8 3.7 1.7 8.7 0.1 3.9 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 RLN37671.1 - 0.0063 16.1 0.3 14 5.2 0.1 3.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 RLN37671.1 - 0.0086 15.6 0.2 3.1 7.3 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 RLN37671.1 - 0.0092 16.1 0.0 0.0092 16.1 0.0 4.0 3 1 0 3 3 2 1 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 RLN37671.1 - 0.012 15.3 0.0 4.7 6.8 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 RLN37671.1 - 0.026 14.3 0.2 3 7.5 0.0 3.0 3 0 0 3 3 2 0 IstB-like ATP binding protein RuvB_N PF05496.12 RLN37671.1 - 0.036 13.8 0.0 3.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_15 PF13175.6 RLN37671.1 - 0.041 13.6 0.2 0.041 13.6 0.2 5.2 2 1 0 3 3 2 0 AAA ATPase domain AAA_5 PF07728.14 RLN37671.1 - 0.057 13.4 2.0 1.9 8.5 0.1 3.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Roc PF08477.13 RLN37671.1 - 0.18 12.1 5.8 2 8.7 0.2 3.4 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 RLN37671.1 - 1.2 9.7 0.0 1.2 9.7 0.0 4.5 5 0 0 5 5 4 0 AAA domain Spc7 PF08317.11 RLN37672.1 - 0.41 9.5 8.5 0.6 8.9 8.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PNP_UDP_1 PF01048.20 RLN37674.1 - 1.2e-25 90.1 0.8 2.1e-25 89.3 0.8 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily DUF621 PF04789.15 RLN37674.1 - 0.13 11.4 1.3 0.24 10.6 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF621) Anoctamin PF04547.12 RLN37675.1 - 2.1e-88 297.1 6.3 2.6e-88 296.8 6.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Raptor_N PF14538.6 RLN37751.1 - 6.8e-52 175.3 0.0 8e-52 175.1 0.0 1.1 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain PIP5K PF01504.18 RLN37752.1 - 5.1e-24 85.0 0.0 6.4e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Myb_DNA-bind_4 PF13837.6 RLN37753.1 - 0.00016 22.0 0.0 0.00029 21.2 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF573 PF04504.14 RLN37753.1 - 0.017 15.8 0.0 0.034 14.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF573 zf-AN1 PF01428.16 RLN37763.1 - 1.5e-09 37.8 8.1 1.5e-09 37.8 8.1 1.5 2 0 0 2 2 2 1 AN1-like Zinc finger zf-A20 PF01754.16 RLN37763.1 - 5.4e-09 35.8 5.3 5.4e-09 35.8 5.3 2.2 2 0 0 2 2 2 1 A20-like zinc finger UPF0547 PF10571.9 RLN37763.1 - 0.012 15.7 6.2 0.012 15.7 6.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RING_4 PF14570.6 RLN37763.1 - 1.1 9.1 10.3 25 4.8 0.0 3.3 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain FYVE_2 PF02318.16 RLN37764.1 - 0.00028 21.1 3.8 0.00068 19.8 3.8 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger zf-C3HC4 PF00097.25 RLN37764.1 - 9.2 6.2 9.6 2e+02 2.0 10.9 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pkinase_Tyr PF07714.17 RLN37765.1 - 2.1e-68 230.4 0.0 3.1e-68 229.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN37765.1 - 4.4e-58 196.7 0.0 6.2e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RLN37765.1 - 0.00071 19.0 0.0 0.0016 17.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 RLN37765.1 - 0.0015 17.5 0.0 0.0028 16.7 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 RLN37765.1 - 0.0057 15.5 0.3 0.028 13.2 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 RLN37765.1 - 0.24 11.3 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family GTP_EFTU PF00009.27 RLN37766.1 - 1.5e-08 34.4 0.1 1.7e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF5336 PF17270.2 RLN37767.1 - 0.035 13.7 0.5 0.11 12.2 0.5 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Sdh_cyt PF01127.22 RLN37767.1 - 7.3 6.6 9.0 1.1 9.3 0.6 3.1 3 1 0 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit FYVE_2 PF02318.16 RLN37768.1 - 0.0052 17.0 4.3 0.011 15.9 4.3 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger DZR PF12773.7 RLN37768.1 - 0.028 14.4 7.6 2.2 8.4 2.0 2.4 1 1 1 2 2 2 0 Double zinc ribbon Zn_Tnp_IS91 PF14319.6 RLN37768.1 - 0.061 13.4 2.6 0.084 12.9 0.5 2.1 2 0 0 2 2 2 0 Transposase zinc-binding domain cobW PF02492.19 RLN37769.1 - 6.8e-29 100.7 0.2 1.2e-28 99.9 0.2 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 RLN37769.1 - 6.4e-10 38.8 0.0 1.9e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 RLN37769.1 - 0.0099 15.4 0.1 0.14 11.7 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 RLN37769.1 - 0.01 16.2 0.8 0.024 15.0 0.2 2.0 2 1 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.17 RLN37769.1 - 0.012 15.4 0.1 0.036 13.8 0.1 1.7 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 RLN37769.1 - 0.029 14.3 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_19 PF13245.6 RLN37769.1 - 0.034 14.5 0.3 0.072 13.4 0.1 1.7 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 RLN37769.1 - 0.044 13.5 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.14 RLN37769.1 - 0.1 10.5 0.0 0.15 10.0 0.0 1.1 1 0 0 1 1 1 0 Helicase ATPase_2 PF01637.18 RLN37769.1 - 0.22 11.4 0.0 0.45 10.4 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Pmp3 PF01679.17 RLN37770.1 - 6e-22 77.6 3.4 7.8e-22 77.2 3.4 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF1295 PF06966.12 RLN37771.1 - 4.8e-62 209.5 0.4 6e-62 209.2 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 RLN37771.1 - 8.4e-07 29.1 0.1 2.6e-06 27.5 0.1 1.9 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 RLN37771.1 - 0.00013 22.3 0.2 0.00013 22.3 0.2 2.6 2 2 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 RLN37771.1 - 0.00034 21.0 1.9 0.00046 20.5 0.0 2.2 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 RLN37771.1 - 0.014 14.2 0.1 0.031 13.1 0.1 1.6 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family DUF3975 PF13126.6 RLN37771.1 - 0.18 12.3 0.9 0.35 11.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3975) Pmp3 PF01679.17 RLN37772.1 - 2.8e-22 78.7 6.0 3.1e-22 78.5 6.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator EI24 PF07264.11 RLN37773.1 - 4.5e-23 82.4 13.4 6e-23 82.0 13.4 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) EI24 PF07264.11 RLN37774.1 - 3.1e-45 154.6 32.1 1.3e-24 87.4 14.0 2.1 2 0 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) DUF996 PF06195.13 RLN37774.1 - 0.0014 18.9 14.2 0.1 12.9 0.6 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF996) DUF3481 PF11980.8 RLN37774.1 - 0.039 13.6 4.5 1.7 8.4 0.3 2.6 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein FAST_1 PF06743.15 RLN37774.1 - 0.2 11.6 1.8 9.4 6.3 0.1 2.5 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 GASA PF02704.14 RLN37774.1 - 1.4 9.1 12.1 6.8 6.9 2.5 2.4 2 0 0 2 2 2 0 Gibberellin regulated protein DUF1772 PF08592.11 RLN37774.1 - 1.8 8.9 16.4 0.18 12.1 1.6 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) DUF898 PF05987.13 RLN37774.1 - 4.7 6.2 26.2 17 4.4 11.0 3.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) Pmp3 PF01679.17 RLN37775.1 - 5.4e-21 74.5 4.4 6e-21 74.4 4.4 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator EI24 PF07264.11 RLN37776.1 - 8e-44 150.0 34.8 2.4e-24 86.6 17.2 2.1 2 0 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) DUF4010 PF13194.6 RLN37776.1 - 0.034 13.8 0.6 0.034 13.8 0.6 3.7 4 1 1 5 5 5 0 Domain of unknown function (DUF4010) Pyr_redox_2 PF07992.14 RLN37791.1 - 2.8e-70 236.9 7.2 2.8e-70 236.9 7.2 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 RLN37791.1 - 2.1e-35 121.3 1.4 2.4e-35 121.1 0.2 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 RLN37791.1 - 1.4e-21 76.9 5.1 2.1e-17 63.5 0.2 3.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 RLN37791.1 - 2.8e-11 43.1 7.9 6.3e-11 42.0 1.0 2.5 2 1 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 RLN37791.1 - 2e-09 37.1 17.3 1.3e-06 27.7 2.2 4.4 3 1 2 5 5 5 2 FAD binding domain FAD_oxidored PF12831.7 RLN37791.1 - 2.9e-09 36.8 5.4 2.9e-09 36.8 5.4 3.1 2 2 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 RLN37791.1 - 1.5e-08 34.3 6.8 4.1e-06 26.3 0.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RLN37791.1 - 1.6e-07 31.5 6.4 0.00014 22.0 0.4 3.3 2 1 0 3 3 3 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 RLN37791.1 - 4.2e-07 29.6 11.7 0.027 13.7 1.0 3.6 3 1 1 4 4 4 3 FAD binding domain HI0933_like PF03486.14 RLN37791.1 - 5.7e-07 28.6 11.4 0.00045 19.0 1.5 4.1 4 0 0 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.21 RLN37791.1 - 3.5e-06 26.5 4.7 0.0034 16.7 0.4 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 RLN37791.1 - 1.9e-05 24.1 0.7 0.0011 18.2 0.1 2.4 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 RLN37791.1 - 0.00015 21.0 2.1 0.029 13.5 0.1 2.6 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 RLN37791.1 - 0.00086 18.5 3.2 0.027 13.5 0.0 3.1 2 1 0 3 3 3 1 Lycopene cyclase protein XdhC_C PF13478.6 RLN37791.1 - 0.0085 16.6 0.1 1.2 9.7 0.0 2.6 2 0 0 2 2 2 1 XdhC Rossmann domain NAD_binding_7 PF13241.6 RLN37791.1 - 0.0098 16.3 2.9 3.6 8.1 0.2 3.4 3 0 0 3 3 3 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 RLN37791.1 - 0.034 13.5 0.2 0.52 9.7 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 RLN37791.1 - 0.089 12.7 0.1 0.089 12.7 0.1 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 RLN37791.1 - 0.15 11.6 21.1 0.81 9.2 0.1 4.2 2 2 1 4 4 4 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 RLN37791.1 - 0.96 8.2 2.8 1.8 7.3 0.8 2.1 2 0 0 2 2 2 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.14 RLN37791.1 - 1 8.9 4.4 0.49 9.9 0.2 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Calreticulin PF00262.18 RLN37792.1 - 7.6e-27 94.1 0.0 8.6e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 Calreticulin family FUN14 PF04930.15 RLN37810.1 - 8.6e-26 90.2 0.6 1.3e-25 89.6 0.6 1.3 1 0 0 1 1 1 1 FUN14 family EF-hand_1 PF00036.32 RLN37810.1 - 7.3e-05 22.0 0.5 0.00016 21.0 0.1 1.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RLN37810.1 - 0.0021 17.8 0.1 0.0065 16.3 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 RLN37810.1 - 0.013 15.0 0.6 0.026 14.0 0.6 1.4 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 RLN37810.1 - 0.12 12.8 0.0 0.4 11.2 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain pair SDF PF00375.18 RLN37811.1 - 1.2e-70 238.5 30.4 4.6e-70 236.6 30.4 1.7 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family TRAM_LAG1_CLN8 PF03798.16 RLN37812.1 - 1.9e-26 93.1 25.2 2.7e-26 92.5 25.2 1.3 1 0 0 1 1 1 1 TLC domain Abhydrolase_9_N PF15420.6 RLN37812.1 - 1.1 9.2 4.8 0.43 10.5 0.1 2.2 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus AbiEi_4 PF13338.6 RLN37813.1 - 0.028 14.6 1.0 0.73 10.0 1.0 2.5 1 1 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin Mago-bind PF09282.10 RLN37814.1 - 3.7e-13 49.1 3.0 8.9e-13 47.9 3.0 1.7 1 0 0 1 1 1 1 Mago binding FlxA PF14282.6 RLN37814.1 - 0.036 14.1 8.6 0.065 13.2 8.6 1.4 1 0 0 1 1 1 0 FlxA-like protein TIP41 PF04176.13 RLN37814.1 - 0.14 11.6 0.5 0.3 10.5 0.5 1.4 1 0 0 1 1 1 0 TIP41-like family KIP1 PF07765.12 RLN37814.1 - 0.14 12.3 0.5 0.25 11.5 0.5 1.3 1 0 0 1 1 1 0 KIP1-like protein zf-CCCH PF00642.24 RLN37815.1 - 0.00024 20.9 13.0 0.0013 18.6 2.9 2.4 1 1 1 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RLN37815.1 - 0.024 14.7 11.4 0.091 12.9 2.0 3.2 2 1 0 2 2 2 0 Zinc finger domain PQQ PF01011.21 RLN37815.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat NPR3 PF03666.13 RLN37815.1 - 0.46 9.2 4.6 0.66 8.7 4.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 zf-CCCH_2 PF14608.6 RLN37815.1 - 2.4 8.7 11.0 6.3 7.4 2.5 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Presenilin PF01080.17 RLN37815.1 - 2.5 6.8 5.0 3.2 6.4 5.0 1.3 1 0 0 1 1 1 0 Presenilin zf-CCCH_4 PF18044.1 RLN37815.1 - 4.4 7.2 11.8 0.87 9.5 1.6 3.0 3 0 0 3 3 3 0 CCCH-type zinc finger FancD2 PF14631.6 RLN37815.1 - 5.6 4.2 5.7 7.8 3.7 5.7 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease U79_P34 PF03064.16 RLN37815.1 - 6.3 6.1 9.3 3.2e+02 0.5 12.0 2.1 2 0 0 2 2 2 0 HSV U79 / HCMV P34 CDC45 PF02724.14 RLN37815.1 - 9.1 4.4 8.2 13 3.9 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein PAP_central PF04928.17 RLN37819.1 - 1.4e-50 171.6 0.1 1.9e-50 171.2 0.1 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 RLN37819.1 - 4.9e-07 29.5 0.0 3e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain Nrap_D2 PF17403.2 RLN37819.1 - 0.00069 19.4 0.0 0.0016 18.3 0.0 1.6 1 1 0 1 1 1 1 Nrap protein PAP/OAS-like domain kleA_kleC PF17383.2 RLN37820.1 - 0.035 14.4 0.1 0.086 13.2 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A Adeno_PV PF03910.13 RLN37842.1 - 0.037 12.7 0.1 0.052 12.2 0.1 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV DnaJ PF00226.31 RLN37844.1 - 5e-05 23.4 0.0 9.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 RLN37845.1 - 2.4e-60 204.2 0.0 1.3e-31 109.9 0.5 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN37845.1 - 2e-21 76.4 0.1 1.2e-15 57.5 0.2 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RLN37845.1 - 0.088 12.1 0.0 11 5.2 0.0 2.4 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 RLN37845.1 - 0.1 11.5 0.0 1 8.2 0.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain ubiquitin PF00240.23 RLN37846.1 - 3.5e-06 26.7 0.0 6.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RLN37846.1 - 0.00055 19.7 0.0 0.00089 19.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IspA PF04279.15 RLN37846.1 - 0.0087 16.3 0.4 0.012 15.7 0.4 1.2 1 0 0 1 1 1 1 Intracellular septation protein A Rad60-SLD_2 PF13881.6 RLN37846.1 - 0.053 13.6 0.0 1.2 9.2 0.0 2.2 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CBS PF00571.28 RLN37847.1 - 2.3e-30 104.8 3.9 4.3e-07 30.3 0.0 4.9 5 0 0 5 5 5 4 CBS domain GAF PF01590.26 RLN37847.1 - 0.0052 17.4 0.1 0.14 12.8 0.0 2.5 2 0 0 2 2 2 1 GAF domain PB1 PF00564.24 RLN37847.1 - 0.0063 16.4 0.1 0.013 15.4 0.1 1.6 1 0 0 1 1 1 1 PB1 domain DAGAT PF03982.13 RLN37848.1 - 5.2e-43 147.0 0.5 8.4e-43 146.4 0.5 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase TerB_C PF15615.6 RLN37848.1 - 1.5 9.1 5.2 0.88 9.9 3.0 1.7 2 0 0 2 2 2 0 TerB-C domain Ras PF00071.22 RLN37849.1 - 4.5e-19 68.6 0.1 5.9e-18 65.0 0.0 2.6 2 1 0 2 2 2 1 Ras family Roc PF08477.13 RLN37849.1 - 1.2e-10 41.7 0.0 5.8e-10 39.4 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase EF_assoc_2 PF08356.12 RLN37849.1 - 1.5e-10 40.9 0.0 4.3e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 RLN37849.1 - 1.8e-06 27.5 0.0 9.3e-06 25.2 0.0 2.0 2 0 0 2 2 2 1 EF hand associated EF-hand_6 PF13405.6 RLN37849.1 - 5.4e-06 25.9 0.2 0.17 11.9 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RLN37849.1 - 1.6e-05 24.1 0.3 0.17 11.5 0.0 2.5 2 0 0 2 2 2 2 EF hand Arf PF00025.21 RLN37849.1 - 4.3e-05 23.0 0.1 0.00014 21.4 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family EF-hand_5 PF13202.6 RLN37849.1 - 5.3e-05 22.5 0.2 0.51 9.9 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RLN37849.1 - 6.5e-05 23.3 0.2 0.44 11.0 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair MMR_HSR1 PF01926.23 RLN37849.1 - 0.00062 19.8 0.0 0.0054 16.8 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RLN37849.1 - 0.012 15.1 0.1 0.067 12.7 0.0 2.1 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RLN37849.1 - 0.14 12.0 0.2 2.5 8.0 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase RabGAP-TBC PF00566.18 RLN37850.1 - 9.1e-37 126.8 0.4 1.3e-36 126.3 0.4 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_5 PF13857.6 RLN37850.1 - 2.1e-10 40.7 0.6 2.4e-07 30.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN37850.1 - 6.9e-08 32.9 0.1 1.5e-07 31.9 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN37850.1 - 7.7e-07 29.6 0.0 1.7e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN37850.1 - 9.5e-05 22.5 0.5 0.079 13.6 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 RLN37850.1 - 9.8e-05 22.6 0.2 0.0085 16.5 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Shisa PF13908.6 RLN37850.1 - 0.0098 16.1 2.0 0.026 14.8 2.0 1.7 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Cas_NE0113 PF09623.10 RLN37850.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) PDEase_I PF00233.19 RLN37851.1 - 1.4e-64 218.1 0.1 3.3e-64 216.9 0.1 1.7 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF_2 PF13185.6 RLN37851.1 - 1.4e-08 35.1 0.0 5.2e-06 26.8 0.0 2.7 2 0 0 2 2 2 2 GAF domain Tim17 PF02466.19 RLN37851.1 - 2.2e-05 24.8 0.4 5.2e-05 23.6 0.4 1.6 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family GAF_3 PF13492.6 RLN37851.1 - 0.00049 20.4 0.1 0.18 12.2 0.0 2.9 2 0 0 2 2 2 2 GAF domain HD PF01966.22 RLN37851.1 - 0.03 14.6 0.5 0.069 13.4 0.5 1.7 1 0 0 1 1 1 0 HD domain Pro-kuma_activ PF09286.11 RLN37852.1 - 6.5e-10 39.5 0.0 1.3e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 RLN37852.1 - 0.054 12.7 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Subtilase family Podoplanin PF05808.11 RLN37852.1 - 0.079 13.1 0.1 0.23 11.6 0.1 1.8 2 0 0 2 2 2 0 Podoplanin NHL PF01436.21 RLN37853.1 - 5.5e-23 79.8 20.9 1.1e-05 25.1 0.8 9.9 10 0 0 10 10 10 6 NHL repeat DUF5128 PF17170.4 RLN37853.1 - 1e-05 24.9 0.0 0.026 13.7 0.0 3.3 3 0 0 3 3 3 2 6-bladed beta-propeller Ldl_recept_b PF00058.17 RLN37853.1 - 0.11 12.9 0.0 11 6.6 0.0 3.9 4 1 0 4 4 4 0 Low-density lipoprotein receptor repeat class B TolB_like PF15869.5 RLN37853.1 - 0.14 11.4 0.0 0.87 8.8 0.0 2.1 2 0 0 2 2 2 0 TolB-like 6-blade propeller-like DAO PF01266.24 RLN37854.1 - 6.8e-52 177.2 0.0 7.7e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase PALP PF00291.25 RLN37855.1 - 4.4e-22 78.8 0.0 5.5e-14 52.3 0.0 2.1 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme BBS2_N PF14781.6 RLN37855.1 - 0.052 13.5 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal Ank_4 PF13637.6 RLN37856.1 - 4.3e-13 49.5 0.2 0.02 15.5 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN37856.1 - 4.9e-12 46.3 0.7 2.5e-07 31.2 0.5 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 RLN37856.1 - 1.7e-09 37.7 0.2 0.15 12.6 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 RLN37856.1 - 3.1e-08 33.2 0.1 0.077 13.6 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 RLN37856.1 - 7.5e-08 32.5 1.9 1.9e-05 24.8 0.6 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Baculo_gp64 PF03273.13 RLN37856.1 - 0.15 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family OmdA PF13376.6 RLN37856.1 - 0.36 10.9 0.0 0.36 10.9 0.0 3.5 4 0 0 4 4 4 0 Bacteriocin-protection, YdeI or OmpD-Associated Peptidase_M1_N PF17900.1 RLN37857.1 - 8.8e-18 65.1 0.0 1.3e-17 64.5 0.0 1.3 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 RLN37857.1 - 4.1e-07 29.8 0.0 6.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 RLN37858.1 - 5.9e-20 71.4 0.1 9.4e-20 70.8 0.1 1.3 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1 PF01433.20 RLN37858.1 - 9.6e-05 22.0 0.0 0.17 11.4 0.0 2.3 1 1 1 2 2 2 2 Peptidase family M1 domain Sugar_tr PF00083.24 RLN37859.1 - 5.5e-99 332.1 27.5 6.7e-99 331.8 27.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN37859.1 - 3.6e-27 95.2 27.8 2.3e-21 76.1 8.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Rad17 PF03215.15 RLN37859.1 - 4e-15 56.2 0.0 1.2e-14 54.6 0.0 1.7 2 0 0 2 2 2 1 Rad17 P-loop domain zf-RanBP PF00641.18 RLN37859.1 - 0.00087 18.6 1.6 0.0022 17.3 1.6 1.8 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others AAA_33 PF13671.6 RLN37859.1 - 0.0014 18.8 0.0 0.0075 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN37859.1 - 0.0038 17.6 0.0 0.0092 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RLN37859.1 - 0.0059 16.9 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 RLN37859.1 - 0.012 16.1 0.0 0.024 15.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RLN37859.1 - 0.035 14.7 0.0 0.11 13.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_assoc_2 PF16193.5 RLN37859.1 - 0.041 14.2 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA C-terminal domain RNA_helicase PF00910.22 RLN37859.1 - 0.079 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase CbtA PF09490.10 RLN37859.1 - 0.083 12.7 0.2 0.083 12.7 0.2 2.2 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) ABC_tran PF00005.27 RLN37859.1 - 0.09 13.3 0.0 0.36 11.4 0.0 2.0 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 RLN37859.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 RLN37859.1 - 0.15 11.3 0.1 1.2 8.4 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 RLN37859.1 - 0.23 11.9 0.0 0.43 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain CHAT PF12770.7 RLN37860.1 - 5.6e-10 39.1 0.0 2.7e-09 36.8 0.0 2.0 1 1 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 RLN37860.1 - 3.7e-09 36.8 0.7 1.8e-07 31.3 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_16 PF13191.6 RLN37860.1 - 6.7e-08 33.1 0.0 3.7e-07 30.7 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain TPR_2 PF07719.17 RLN37860.1 - 8.4e-06 25.5 0.8 0.011 15.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat NACHT PF05729.12 RLN37860.1 - 1.3e-05 25.2 0.0 2.7e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 RLN37860.1 - 0.00038 20.8 0.0 0.0013 19.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain TPR_10 PF13374.6 RLN37860.1 - 0.0054 16.6 0.5 0.081 12.8 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_25 PF13481.6 RLN37860.1 - 0.013 15.1 0.2 0.039 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain TPR_1 PF00515.28 RLN37860.1 - 0.022 14.6 0.3 0.23 11.3 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat NTPase_1 PF03266.15 RLN37860.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 RLN37860.1 - 0.15 11.2 0.0 0.35 10.0 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain DDE_Tnp_1_7 PF13843.6 RLN37861.1 - 4.8e-26 91.9 0.0 6.8e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 TEX19 PF15553.6 RLN37861.1 - 0.045 13.7 1.5 0.081 12.9 1.5 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 Globin PF00042.22 RLN37862.1 - 7.6e-05 23.2 0.1 0.0005 20.6 0.1 2.2 1 1 0 1 1 1 1 Globin Ank_4 PF13637.6 RLN37863.1 - 2.6e-28 98.0 0.1 1.7e-11 44.4 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN37863.1 - 1.3e-21 77.0 0.1 8.6e-15 55.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RLN37863.1 - 1.1e-20 73.1 0.6 2.9e-05 24.3 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 RLN37863.1 - 6.1e-19 66.1 0.7 6.7e-06 26.1 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 RLN37863.1 - 5.8e-18 64.7 1.0 2.5e-09 37.2 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) WD40 PF00400.32 RLN37864.1 - 7.6e-66 216.5 17.2 8.6e-08 32.7 0.1 11.2 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 RLN37864.1 - 8.9e-40 135.9 0.0 1.5e-39 135.2 0.0 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 RLN37864.1 - 6.6e-16 58.4 4.3 0.00029 21.1 0.0 7.8 4 3 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN37864.1 - 3.1e-11 42.8 5.9 0.19 10.6 0.0 7.1 3 3 5 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RLN37864.1 - 5.5e-07 28.6 7.2 0.086 11.5 0.0 5.9 5 3 1 6 6 6 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 RLN37864.1 - 1.9e-05 23.4 0.2 0.019 13.5 0.1 3.8 3 1 2 5 5 5 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 RLN37864.1 - 0.00095 18.0 0.0 8.4 5.0 0.0 4.2 2 1 2 4 4 4 2 Nup133 N terminal like VID27 PF08553.10 RLN37864.1 - 0.0096 15.0 0.0 0.033 13.2 0.0 1.8 2 0 0 2 2 2 1 VID27 C-terminal WD40-like domain nos_propeller PF18764.1 RLN37864.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Nitrous oxide reductase propeller repeat WD40_like PF17005.5 RLN37864.1 - 0.16 11.3 0.0 2.1 7.6 0.0 2.6 3 0 0 3 3 3 0 WD40-like domain FISNA PF14484.6 RLN37865.1 - 0.074 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Fish-specific NACHT associated domain DUF727 PF05303.12 RLN37865.1 - 0.13 12.4 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF727) DASH_Ask1 PF08655.10 RLN37865.1 - 0.13 12.1 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 DASH complex subunit Ask1 TauE PF01925.19 RLN37867.1 - 7.5e-10 38.8 25.6 9.7e-09 35.2 25.8 2.5 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE DUF2431 PF10354.9 RLN37868.1 - 6.6e-45 153.4 0.0 1.1e-44 152.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) COE1_DBD PF16422.5 RLN37868.1 - 0.093 12.2 0.1 0.19 11.1 0.0 1.5 2 0 0 2 2 2 0 Transcription factor COE1 DNA-binding domain zf-C3HC4_3 PF13920.6 RLN37869.1 - 1.2e-09 37.8 9.9 1.2e-09 37.8 9.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN37869.1 - 3e-09 36.5 10.6 7.6e-09 35.3 10.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN37869.1 - 8.8e-08 31.9 7.9 1.9e-07 30.8 7.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN37869.1 - 6.8e-07 29.2 11.9 6.8e-07 29.2 11.9 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RLN37869.1 - 1.2e-06 28.3 11.5 1.2e-06 28.3 11.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN37869.1 - 1.4e-06 28.5 10.2 4e-06 27.0 10.2 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.6 RLN37869.1 - 2.2e-05 24.3 2.7 4.4e-05 23.3 2.7 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 RLN37869.1 - 0.00059 20.1 6.5 0.0019 18.4 6.5 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RLN37869.1 - 0.0021 18.0 9.1 0.0055 16.7 9.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 RLN37869.1 - 0.053 13.3 8.4 0.15 11.9 8.4 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 RLN37869.1 - 0.14 12.1 7.1 0.3 11.0 7.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RLN37869.1 - 0.39 10.8 4.0 0.91 9.6 4.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 RLN37869.1 - 0.39 10.9 7.6 1.3 9.3 7.6 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 RLN37869.1 - 6.3 7.0 12.3 0.21 11.7 4.8 2.3 2 0 0 2 2 2 0 Zinc-binding RING-finger Fungal_TACC PF12709.7 RLN37870.1 - 0.04 14.4 0.6 0.04 14.4 0.6 5.6 4 3 1 5 5 5 0 Fungal Transforming acidic coiled-coil (TACC) proteins Sugar_tr PF00083.24 RLN37871.1 - 1.2e-50 172.7 20.5 1.9e-30 106.1 6.0 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RLN37871.1 - 8.3e-16 57.8 23.3 1.9e-12 46.8 7.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1115 PF06544.12 RLN37871.1 - 9.1e-11 42.1 0.0 1.6e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) CUE PF02845.16 RLN37882.1 - 3.6e-06 26.5 1.3 4.8e-06 26.2 0.1 2.0 2 0 0 2 2 2 1 CUE domain Methyltransf_25 PF13649.6 RLN37884.1 - 1.7e-06 28.7 0.0 0.00018 22.1 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 RLN37884.1 - 0.00017 21.1 0.0 0.00032 20.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 RLN37884.1 - 0.0033 17.3 0.0 0.01 15.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN37884.1 - 0.0086 16.7 0.0 0.043 14.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN37884.1 - 0.081 13.7 0.0 0.22 12.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 RLN37884.1 - 0.1 12.5 0.0 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 RLN37884.1 - 0.17 11.5 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain ATP-synt_ab PF00006.25 RLN37885.1 - 6.8e-22 78.2 0.0 1.1e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Nif11 PF07862.11 RLN37885.1 - 0.076 13.3 0.1 0.41 11.0 0.1 2.2 1 0 0 1 1 1 0 Nif11 domain SesA PF17107.5 RLN37886.1 - 0.0054 16.9 0.0 0.0073 16.5 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Pkinase_Tyr PF07714.17 RLN37887.1 - 3.2e-43 147.9 0.0 4.9e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN37887.1 - 3.7e-33 115.0 0.0 5.8e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DZR PF12773.7 RLN37887.1 - 0.0002 21.3 0.9 0.00062 19.7 0.9 1.8 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 RLN37887.1 - 0.00028 21.6 0.6 0.00068 20.3 0.6 1.7 1 0 0 1 1 1 1 zinc-ribbon family zinc_ribbon_2 PF13240.6 RLN37887.1 - 0.0038 16.9 3.6 0.0092 15.7 3.6 1.7 1 0 0 1 1 1 1 zinc-ribbon domain UPF0547 PF10571.9 RLN37887.1 - 0.0053 16.8 3.3 0.0058 16.7 0.8 2.3 2 0 0 2 2 2 1 Uncharacterised protein family UPF0547 APH PF01636.23 RLN37887.1 - 0.019 14.9 0.6 0.085 12.8 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 RLN37887.1 - 0.039 13.5 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family zf-ribbon_3 PF13248.6 RLN37887.1 - 0.12 11.9 2.4 0.39 10.2 2.4 2.0 1 0 0 1 1 1 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 RLN37887.1 - 3.3 7.3 5.5 3 7.4 3.1 2.3 2 1 0 2 2 2 0 TFIIB zinc-binding Peptidase_S8 PF00082.22 RLN37888.1 - 1.5e-79 267.3 2.0 2.2e-79 266.8 2.0 1.2 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 RLN37888.1 - 1.1e-59 201.1 0.0 1.9e-59 200.4 0.0 1.4 1 0 0 1 1 1 1 Tripeptidyl peptidase II PH_2 PF08458.10 RLN37888.1 - 0.043 14.2 0.0 0.087 13.2 0.0 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Pkinase_Tyr PF07714.17 RLN37889.1 - 4e-42 144.3 0.0 8.7e-42 143.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN37889.1 - 3.1e-35 121.8 0.0 1.9e-34 119.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain UPF0547 PF10571.9 RLN37889.1 - 2.1e-05 24.5 1.3 5.3e-05 23.2 1.3 1.7 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 DZR PF12773.7 RLN37889.1 - 0.00023 21.1 0.6 0.00061 19.8 0.6 1.6 1 0 0 1 1 1 1 Double zinc ribbon ABC1 PF03109.16 RLN37889.1 - 0.00059 20.0 3.3 0.68 10.1 0.0 3.3 3 1 0 3 3 3 2 ABC1 family zinc_ribbon_15 PF17032.5 RLN37889.1 - 0.00079 20.1 0.2 0.0022 18.7 0.2 1.8 1 0 0 1 1 1 1 zinc-ribbon family zinc_ribbon_2 PF13240.6 RLN37889.1 - 0.0032 17.1 1.7 0.0032 17.1 1.7 2.2 2 0 0 2 2 2 1 zinc-ribbon domain TcpS PF17456.2 RLN37889.1 - 0.0032 17.5 0.9 0.0062 16.6 0.2 1.8 2 0 0 2 2 1 1 Toxin-coregulated pilus protein S RIO1 PF01163.22 RLN37889.1 - 0.0038 16.8 1.0 0.19 11.3 0.0 2.7 2 1 0 2 2 2 1 RIO1 family TetR_C_29 PF17938.1 RLN37889.1 - 0.016 15.3 0.4 0.041 14.0 0.4 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain APH PF01636.23 RLN37889.1 - 0.029 14.3 0.1 0.084 12.8 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF2116 PF09889.9 RLN37889.1 - 0.073 13.1 0.3 0.073 13.1 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) FlgN PF05130.12 RLN37889.1 - 0.29 11.6 6.8 8.9 6.8 0.1 2.4 2 0 0 2 2 2 0 FlgN protein DUF148 PF02520.17 RLN37889.1 - 0.66 10.1 9.8 0.87 9.7 2.9 3.3 2 1 1 3 3 3 0 Domain of unknown function DUF148 Rrn6 PF10214.9 RLN37889.1 - 1.1 7.7 4.1 1.7 7.1 0.2 1.9 1 1 1 2 2 2 0 RNA polymerase I-specific transcription-initiation factor zf-ribbon_3 PF13248.6 RLN37889.1 - 1.1 8.8 6.7 0.19 11.2 1.8 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Laminin_I PF06008.14 RLN37889.1 - 1.5 8.5 9.3 0.38 10.4 5.1 1.9 2 0 0 2 2 2 0 Laminin Domain I THOC7 PF05615.13 RLN37889.1 - 8.2 6.7 11.0 1.6 9.0 4.2 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 SesA PF17107.5 RLN37890.1 - 0.0021 18.2 0.2 0.0055 16.9 0.1 1.7 1 1 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases RNase_T PF00929.24 RLN37890.1 - 0.04 14.4 0.3 0.049 14.2 0.3 1.1 1 0 0 1 1 1 0 Exonuclease Nramp PF01566.18 RLN37891.1 - 7.1e-119 396.9 14.9 7.1e-119 396.9 14.9 2.0 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein CTD_bind PF04818.13 RLN37892.1 - 0.15 12.9 0.5 0.65 10.9 0.0 2.2 2 1 0 2 2 2 0 RNA polymerase II-binding domain. Iso_dh PF00180.20 RLN37893.1 - 1.8e-100 336.5 0.0 1.3e-98 330.4 0.0 2.4 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Mucin PF01456.17 RLN37894.1 - 0.00027 20.9 8.7 0.00027 20.9 8.7 2.6 2 1 0 2 2 2 1 Mucin-like glycoprotein RhlB PF12300.8 RLN37894.1 - 2.1 8.5 17.7 1.5 9.0 3.5 2.3 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB RNA_pol_Rpc4 PF05132.14 RLN37894.1 - 4.8 7.6 8.0 13 6.2 0.7 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 CCDC53 PF10152.9 RLN37894.1 - 5.2 7.5 11.2 2.4 8.6 0.3 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex TPH PF13868.6 RLN37897.1 - 1.8e-38 132.0 109.7 1.8e-38 132.0 109.7 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Metallophos PF00149.28 RLN37898.1 - 8.4e-19 68.9 1.4 1.5e-18 68.0 1.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 RLN37898.1 - 2.2e-18 66.6 7.4 2.2e-18 66.6 7.4 2.7 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 RLN37898.1 - 1.6e-15 57.7 0.1 5.9e-15 55.9 0.0 2.1 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C DUF2369 PF10179.9 RLN37898.1 - 0.29 11.6 2.2 0.67 10.4 2.2 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) Dynamin_N PF00350.23 RLN37899.1 - 1.8e-10 41.1 0.0 4.4e-06 26.9 0.0 2.6 2 1 1 3 3 3 2 Dynamin family MMR_HSR1 PF01926.23 RLN37899.1 - 2.9e-05 24.1 0.0 8.5e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF5600 PF18150.1 RLN37899.1 - 0.049 14.2 0.1 0.89 10.2 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5600) FeoB_N PF02421.18 RLN37899.1 - 0.05 13.1 0.0 7.8 6.0 0.0 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RLN37899.1 - 0.063 13.2 0.0 0.85 9.5 0.0 2.5 3 0 0 3 3 3 0 RsgA GTPase AAA_18 PF13238.6 RLN37899.1 - 0.093 13.3 0.0 16 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 RLN37899.1 - 0.23 10.6 0.0 3.8 6.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit BUD22 PF09073.10 RLN37900.1 - 3.2e-10 40.0 65.9 3.7e-10 39.8 46.1 3.8 1 1 1 2 2 2 2 BUD22 AZUL PF16558.5 RLN37901.1 - 8.1e-14 51.6 3.9 2e-13 50.4 3.9 1.7 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A CDC45 PF02724.14 RLN37901.1 - 0.32 9.2 5.1 0.42 8.9 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Glycos_transf_3 PF00591.21 RLN37902.1 - 5.8e-83 278.4 0.1 8.3e-83 277.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 RLN37902.1 - 2.2e-14 53.0 1.4 4.5e-14 52.0 1.4 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Attacin_N PF03768.15 RLN37902.1 - 0.0055 16.8 2.3 0.93 9.7 0.8 2.6 2 0 0 2 2 2 2 Attacin, N-terminal region DENN PF02141.21 RLN37903.1 - 2.9e-08 33.9 0.3 6.4e-08 32.8 0.3 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain IPK PF03770.16 RLN37903.1 - 0.14 12.0 0.3 1.8 8.4 0.8 2.2 2 0 0 2 2 2 0 Inositol polyphosphate kinase ubiquitin PF00240.23 RLN37904.1 - 9.2e-06 25.3 0.0 2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 RLN37904.1 - 0.012 15.6 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CCDC14 PF15254.6 RLN37904.1 - 0.19 10.4 8.0 0.24 10.0 8.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 DUF647 PF04884.14 RLN37905.1 - 5.2e-90 301.3 2.3 7.2e-90 300.8 2.3 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DHHC PF01529.20 RLN37906.1 - 2.1e-32 112.0 6.4 2.1e-32 112.0 6.4 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 RLN37906.1 - 9.2e-17 61.4 0.8 3.3e-06 27.6 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN37906.1 - 2.4e-16 59.8 6.8 4.3e-06 27.2 0.6 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN37906.1 - 6.9e-12 44.5 2.2 0.2 12.3 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 RLN37906.1 - 8.3e-10 38.7 5.1 0.00089 19.5 0.1 4.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN37906.1 - 3.5e-07 30.4 1.0 0.36 11.4 0.1 4.5 4 0 0 4 4 4 2 Ankyrin repeat MRP-63 PF14978.6 RLN37906.1 - 0.14 12.8 0.1 0.39 11.4 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 IGFBP PF00219.18 RLN37906.1 - 0.57 10.9 5.6 1.1 10.0 5.6 1.4 1 0 0 1 1 1 0 Insulin-like growth factor binding protein Cornichon PF03311.14 RLN37906.1 - 0.67 10.3 0.0 0.67 10.3 0.0 3.0 3 1 0 3 3 3 0 Cornichon protein Pkinase PF00069.25 RLN37907.1 - 2.1e-38 132.2 0.0 2.8e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN37907.1 - 4.5e-17 62.2 0.0 6.2e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN37907.1 - 1.5e-08 34.9 2.3 3.7e-08 33.6 1.7 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN37907.1 - 3.1e-06 26.7 0.0 4.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RLN37907.1 - 0.0094 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Sharpin_PH PF16764.5 RLN37907.1 - 0.028 14.2 0.1 0.65 9.8 0.0 2.5 2 0 0 2 2 2 0 Sharpin PH domain Choline_kinase PF01633.20 RLN37907.1 - 0.087 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase His_Phos_1 PF00300.22 RLN37908.1 - 6.2e-35 120.7 0.0 8.7e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Vert_HS_TF PF06546.11 RLN37908.1 - 0.02 14.6 6.5 0.027 14.1 6.5 1.1 1 0 0 1 1 1 0 Vertebrate heat shock transcription factor Lectin_legB PF00139.19 RLN37908.1 - 0.028 14.0 0.2 0.047 13.2 0.2 1.3 1 0 0 1 1 1 0 Legume lectin domain Glycos_transf_4 PF00953.21 RLN37909.1 - 2.6e-33 115.3 6.3 2.6e-33 115.3 6.3 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 4 LBR_tudor PF09465.10 RLN37910.1 - 0.0021 17.8 0.4 0.26 11.1 0.0 2.5 2 0 0 2 2 2 2 Lamin-B receptor of TUDOR domain Med26 PF08711.11 RLN37910.1 - 0.01 15.8 0.2 0.025 14.6 0.2 1.6 1 0 0 1 1 1 0 TFIIS helical bundle-like domain 53-BP1_Tudor PF09038.10 RLN37910.1 - 0.15 12.0 0.2 3.8 7.5 0.0 2.8 3 0 0 3 3 3 0 Tumour suppressor p53-binding protein-1 Tudor MIOX PF05153.15 RLN37960.1 - 1e-11 44.9 0.1 1.2e-11 44.7 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase MIOX PF05153.15 RLN37961.1 - 2.2e-06 27.5 0.5 2.7e-06 27.2 0.5 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase Aa_trans PF01490.18 RLN37963.1 - 4.4e-40 137.6 16.2 6.5e-40 137.1 16.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Flp1_like PF16982.5 RLN37963.1 - 0.011 15.1 2.0 0.011 15.1 2.0 2.3 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain DUF3675 PF12428.8 RLN37963.1 - 0.14 12.8 0.9 0.79 10.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) DUF5383 PF17355.2 RLN37963.1 - 0.26 11.7 0.0 0.26 11.7 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5383) YfhO PF09586.10 RLN37963.1 - 5.9 5.0 6.7 0.26 9.4 0.5 1.7 2 0 0 2 2 2 0 Bacterial membrane protein YfhO ABC2_membrane_3 PF12698.7 RLN37964.1 - 3.5e-62 210.5 50.4 7.9e-46 156.7 18.7 3.1 2 2 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 RLN37964.1 - 1.8e-56 190.5 0.0 2.1e-27 96.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN37964.1 - 2.6e-20 73.5 0.5 7.5e-07 29.2 0.0 4.4 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RLN37964.1 - 3.6e-06 27.0 0.0 0.12 12.1 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 RLN37964.1 - 3.9e-05 24.2 1.7 0.011 16.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 RLN37964.1 - 0.00018 21.5 0.2 0.0081 16.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 RLN37964.1 - 0.0052 16.3 0.1 4.9 6.5 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RLN37964.1 - 0.0052 16.5 1.2 0.093 12.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN37964.1 - 0.0079 16.6 0.0 6.2 7.2 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.23 RLN37964.1 - 0.0084 16.2 0.0 1.3 9.1 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 RLN37964.1 - 0.0097 15.6 0.7 0.67 9.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC2_membrane PF01061.24 RLN37964.1 - 0.011 15.1 55.7 0.24 10.8 22.7 4.3 4 0 0 4 4 4 0 ABC-2 type transporter SbcCD_C PF13558.6 RLN37964.1 - 0.016 15.4 0.0 8.9 6.6 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 RLN37964.1 - 0.048 13.9 0.6 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 RLN37964.1 - 0.089 12.2 0.6 10 5.6 0.1 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 RLN37964.1 - 0.13 12.4 0.4 8.2 6.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 RLN37964.1 - 0.15 11.7 4.1 6 6.4 0.4 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA PF00004.29 RLN37964.1 - 0.2 12.1 0.4 38 4.7 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MukB PF04310.12 RLN37964.1 - 0.43 10.4 2.8 9.8 5.9 0.2 2.5 2 0 0 2 2 2 0 MukB N-terminal cNMP_binding PF00027.29 RLN37965.1 - 2.1e-16 59.8 0.1 4.7e-16 58.6 0.0 1.6 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain EGF_2 PF07974.13 RLN37966.1 - 1.9e-10 41.0 83.0 5.1e-05 23.5 3.6 8.7 9 0 0 9 9 9 7 EGF-like domain EGF PF00008.27 RLN37966.1 - 0.00046 20.4 57.7 0.012 15.9 2.3 9.0 8 0 0 8 8 8 4 EGF-like domain hEGF PF12661.7 RLN37966.1 - 0.025 15.2 3.5 0.025 15.2 3.5 9.1 9 0 0 9 9 9 0 Human growth factor-like EGF Laminin_EGF PF00053.24 RLN37966.1 - 0.62 10.2 72.7 0.053 13.7 7.1 6.3 6 1 1 7 7 7 0 Laminin EGF domain Ank_2 PF12796.7 RLN37967.1 - 1.3e-15 57.7 0.5 1.5e-11 44.7 0.2 2.8 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN37967.1 - 1.8e-13 50.4 0.6 4.5e-06 26.8 0.0 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN37967.1 - 9.5e-12 44.0 0.2 0.012 16.1 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 RLN37967.1 - 4.9e-11 42.9 2.2 0.00089 19.8 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN37967.1 - 8.8e-08 32.3 0.5 0.015 15.7 0.0 4.7 4 1 0 4 4 4 1 Ankyrin repeat Cu-oxidase_2 PF07731.14 RLN37976.1 - 1.3e-33 115.6 15.6 3.2e-28 98.2 5.2 4.2 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN37976.1 - 1.1e-32 112.5 2.4 9.7e-30 103.0 0.2 3.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 RLN37976.1 - 3.6e-27 95.4 0.1 2e-26 93.0 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 RLN37977.1 - 7.1e-37 126.2 6.1 1.4e-30 105.8 0.8 4.5 3 2 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN37977.1 - 4.4e-31 107.4 7.1 3.6e-28 98.0 0.2 4.4 5 0 0 5 5 5 2 Multicopper oxidase Cu-oxidase PF00394.22 RLN37977.1 - 4.1e-29 101.7 0.0 2.4e-28 99.3 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase Elongin_A PF06881.11 RLN38015.1 - 0.052 14.1 0.7 0.16 12.5 0.7 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A TylF PF05711.11 RLN38015.1 - 0.17 11.1 1.1 2 7.6 0.1 2.3 2 0 0 2 2 2 0 Macrocin-O-methyltransferase (TylF) FYVE_2 PF02318.16 RLN38016.1 - 0.0017 18.6 10.6 0.0017 18.6 10.6 1.7 2 0 0 2 2 2 1 FYVE-type zinc finger FYVE PF01363.21 RLN38016.1 - 0.023 14.8 16.2 0.063 13.4 16.2 1.7 1 0 0 1 1 1 0 FYVE zinc finger ART PF01129.18 RLN38016.1 - 0.031 13.6 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase Ion_trans PF00520.31 RLN38017.1 - 1e-17 64.2 9.1 1e-17 64.2 9.1 1.9 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 RLN38017.1 - 1.2e-10 41.2 3.2 1.2e-10 41.2 3.2 2.5 2 0 0 2 2 2 1 Ion channel Pkinase_Tyr PF07714.17 RLN38026.1 - 2.7e-44 151.4 0.0 5.1e-44 150.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN38026.1 - 3e-38 131.7 0.0 6.6e-38 130.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.23 RLN38026.1 - 3.2e-34 115.9 16.0 0.0012 18.8 0.0 11.5 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN38026.1 - 4.6e-07 30.2 16.5 0.3 11.6 0.1 6.3 4 1 3 7 7 6 4 HEAT-like repeat Atx10homo_assoc PF09759.9 RLN38026.1 - 6.9e-06 26.0 1.2 2.4 8.2 0.0 5.1 2 1 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 RLN38026.1 - 1.1e-05 25.0 0.4 0.059 12.8 0.0 3.8 2 1 0 3 3 3 2 Armadillo-like V-ATPase_H_N PF03224.14 RLN38026.1 - 4.5e-05 22.9 0.0 0.47 9.7 0.0 3.4 1 1 1 3 3 3 2 V-ATPase subunit H HEAT_2 PF13646.6 RLN38026.1 - 0.00012 22.3 30.6 0.017 15.5 4.4 6.1 2 1 7 9 9 9 5 HEAT repeats UNC45-central PF11701.8 RLN38026.1 - 0.0021 18.0 7.0 0.56 10.2 0.1 4.9 3 2 2 5 5 5 1 Myosin-binding striated muscle assembly central ABC1 PF03109.16 RLN38026.1 - 0.0029 17.7 0.0 0.0092 16.1 0.0 1.8 1 0 0 1 1 1 1 ABC1 family DUF397 PF04149.12 RLN38026.1 - 0.018 15.1 0.1 14 5.8 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF397) APH PF01636.23 RLN38026.1 - 0.024 14.6 0.1 0.075 12.9 0.1 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family DZR PF12773.7 RLN38026.1 - 0.13 12.3 0.3 0.27 11.3 0.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 RLN38026.1 - 0.14 12.9 0.1 0.3 11.9 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon family HEAT PF02985.22 RLN38026.1 - 0.14 12.5 14.0 35 5.0 0.1 7.1 6 0 0 6 6 6 0 HEAT repeat zinc-ribbon_6 PF10005.9 RLN38026.1 - 0.23 12.2 1.7 0.75 10.5 0.5 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2 PF00096.26 RLN38032.1 - 1.1e-09 38.1 16.7 0.085 13.3 1.7 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN38032.1 - 3.9e-09 36.6 23.3 0.086 13.7 0.7 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_2 PF12756.7 RLN38032.1 - 6.9e-05 23.1 10.9 0.59 10.5 0.1 4.6 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 RLN38032.1 - 0.00014 22.0 2.5 0.3 11.4 0.0 3.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RLN38032.1 - 0.00024 21.0 15.6 0.4 10.8 0.4 4.8 4 0 0 4 4 4 2 C2H2-type zinc finger ADK_lid PF05191.14 RLN38032.1 - 0.00069 19.5 6.6 1.3 9.1 0.2 4.6 3 2 1 4 4 4 2 Adenylate kinase, active site lid zf-ribbon_3 PF13248.6 RLN38032.1 - 0.003 16.9 6.9 0.47 9.9 0.0 4.4 4 0 0 4 4 4 1 zinc-ribbon domain zf-met PF12874.7 RLN38032.1 - 0.013 15.8 9.3 5.5 7.5 0.2 5.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type HTH_35 PF13693.6 RLN38032.1 - 0.079 13.0 0.1 0.26 11.3 0.1 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding zf-LYAR PF08790.11 RLN38032.1 - 0.083 12.8 4.6 5.4 7.0 0.1 4.0 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-BED PF02892.15 RLN38032.1 - 0.096 12.7 8.6 2 8.5 0.3 4.2 4 0 0 4 4 4 0 BED zinc finger CpXC PF14353.6 RLN38032.1 - 0.12 12.5 14.0 0.91 9.6 3.7 4.7 3 1 0 4 4 4 0 CpXC protein zinc_ribbon_4 PF13717.6 RLN38032.1 - 0.13 12.2 13.6 7.4 6.6 0.6 4.5 4 0 0 4 4 4 0 zinc-ribbon domain zf_UBZ PF18439.1 RLN38032.1 - 0.21 11.2 8.2 11 5.7 0.2 4.5 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Rad50_zn_hook PF04423.14 RLN38032.1 - 1.5 8.8 4.6 7.9 6.4 0.1 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF2256 PF10013.9 RLN38032.1 - 2.1 8.5 17.3 2.1 8.5 0.4 4.5 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_2 PF13240.6 RLN38032.1 - 2.5 7.9 12.7 8.3 6.3 0.1 4.5 4 0 0 4 4 4 0 zinc-ribbon domain zf_C2H2_10 PF18414.1 RLN38032.1 - 3.4 7.3 6.9 14 5.3 0.1 3.0 3 0 0 3 3 2 0 C2H2 type zinc-finger DZR PF12773.7 RLN38032.1 - 6.3 6.9 20.8 1.8e+04 -6.8 20.8 3.5 1 1 0 1 1 0 0 Double zinc ribbon HypA PF01155.19 RLN38032.1 - 9.4 6.3 16.4 0.72 9.9 0.8 3.9 2 1 2 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_6 PF13912.6 RLN38033.1 - 1.4e-11 44.1 11.9 0.014 15.4 0.2 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_4 PF13894.6 RLN38033.1 - 2.4e-11 43.5 18.8 0.0075 17.0 0.2 5.2 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 RLN38033.1 - 4.2e-10 39.5 13.6 0.00089 19.6 0.6 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RLN38033.1 - 5.2e-06 26.6 5.7 3.8 7.9 0.2 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 RLN38033.1 - 2.2e-05 24.1 6.1 0.29 10.9 0.2 3.6 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-BED PF02892.15 RLN38033.1 - 3.1e-05 23.9 0.8 0.52 10.4 0.1 3.5 3 0 0 3 3 3 2 BED zinc finger zf_UBZ PF18439.1 RLN38033.1 - 4.6e-05 22.9 4.1 1.9 8.2 0.0 4.5 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger ADK_lid PF05191.14 RLN38033.1 - 0.0072 16.3 0.5 1.6 8.7 0.3 3.1 1 1 1 2 2 2 2 Adenylate kinase, active site lid zf-C2HC_2 PF13913.6 RLN38033.1 - 0.0092 15.9 16.6 0.83 9.6 0.3 4.7 5 0 0 5 5 5 2 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 RLN38033.1 - 0.012 16.0 12.3 2.9 8.5 1.2 4.2 4 0 0 4 4 3 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 RLN38033.1 - 0.027 14.8 6.3 25 5.3 0.0 4.4 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 RLN38033.1 - 0.032 14.6 5.4 53 4.4 0.1 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type XPA_N PF01286.18 RLN38033.1 - 0.042 13.9 9.5 9.9 6.3 0.2 4.0 4 0 0 4 4 4 0 XPA protein N-terminal GAGA PF09237.11 RLN38033.1 - 0.044 13.6 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 0 GAGA factor zinc_ribbon_9 PF14369.6 RLN38033.1 - 0.072 13.4 5.0 14 6.0 0.1 3.9 3 0 0 3 3 3 0 zinc-ribbon DUF2256 PF10013.9 RLN38033.1 - 0.11 12.6 12.5 1.4 9.1 0.2 4.4 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-ribbon_3 PF13248.6 RLN38033.1 - 0.12 11.8 12.8 3.5 7.2 0.4 4.2 4 0 0 4 4 4 0 zinc-ribbon domain POPLD PF08170.12 RLN38033.1 - 0.16 12.3 1.5 0.35 11.2 0.2 2.3 2 0 0 2 2 1 0 POPLD (NUC188) domain YhfH PF14149.6 RLN38033.1 - 0.17 11.8 11.4 1.9 8.5 0.7 3.5 3 0 0 3 3 3 0 YhfH-like protein CpXC PF14353.6 RLN38033.1 - 0.26 11.4 14.4 2.4 8.2 3.1 4.8 3 2 1 4 4 4 0 CpXC protein HypA PF01155.19 RLN38033.1 - 0.46 10.5 5.6 2.7 8.0 0.5 2.8 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 RLN38033.1 - 0.62 10.2 10.9 7.9 6.7 0.5 4.0 3 0 0 3 3 3 0 Zinc ribbon domain FYVE PF01363.21 RLN38033.1 - 1 9.6 8.8 41 4.4 0.1 3.9 3 1 0 3 3 3 0 FYVE zinc finger Fer4_24 PF18109.1 RLN38033.1 - 1.3 9.3 4.1 2.3 8.6 0.2 2.8 2 0 0 2 2 2 0 Ferredoxin I 4Fe-4S cluster domain NinG PF05766.12 RLN38033.1 - 1.4 8.8 10.9 0.058 13.3 2.6 2.7 3 0 0 3 3 3 0 Bacteriophage Lambda NinG protein zf-3CxxC_2 PF17180.4 RLN38033.1 - 3.4 8.5 8.4 5.5 7.8 0.8 3.8 1 1 2 3 3 3 0 Zinc-binding domain IBR PF01485.21 RLN38033.1 - 3.7 7.8 6.5 1.4 9.2 1.7 2.5 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Kinesin PF00225.23 RLN38034.1 - 9.8e-101 337.0 1.6 1.7e-100 336.2 1.6 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN38034.1 - 1.2e-20 74.0 0.1 4.6e-20 72.1 0.1 2.1 1 0 0 1 1 1 1 Microtubule binding Csm1_N PF18504.1 RLN38034.1 - 0.037 14.4 1.2 0.037 14.4 1.2 3.6 4 1 0 4 4 4 0 Csm1 N-terminal domain DUF4807 PF16065.5 RLN38034.1 - 0.12 12.0 0.9 1.8 8.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4807) RNase_T PF00929.24 RLN38035.1 - 1e-05 26.2 0.0 2.2e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Exonuclease RRM_1 PF00076.22 RLN38035.1 - 0.0038 17.0 0.0 0.0093 15.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CHDNT PF08073.12 RLN38036.1 - 0.097 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain Urb2 PF10441.9 RLN38037.1 - 6.7e-23 81.7 13.8 1.8e-22 80.3 3.3 3.3 3 0 0 3 3 3 2 Urb2/Npa2 family TetR_C_1 PF02909.17 RLN38037.1 - 0.068 13.0 0.6 1.5 8.6 0.1 3.0 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF3361 PF11841.8 RLN38037.1 - 0.11 12.4 0.4 1.8 8.5 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) DNA_repr_REX1B PF14966.6 RLN38038.1 - 1.4e-18 67.3 5.4 1.2e-17 64.4 3.5 2.6 2 1 0 2 2 2 1 DNA repair REX1-B FAM47 PF14642.6 RLN38038.1 - 0.029 13.9 0.2 0.038 13.5 0.2 1.3 1 0 0 1 1 1 0 FAM47 family Trns_repr_metal PF02583.17 RLN38038.1 - 0.042 14.2 1.6 0.09 13.2 0.4 2.1 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor DUF948 PF06103.11 RLN38038.1 - 0.054 13.8 0.7 0.15 12.3 0.2 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Se-cys_synth_N PF12390.8 RLN38038.1 - 0.15 12.3 3.3 11 6.4 0.1 3.2 3 0 0 3 3 3 0 Selenocysteine synthase N terminal Metallophos PF00149.28 RLN38039.1 - 6.6e-09 36.6 0.1 1.1e-08 35.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Arm PF00514.23 RLN38041.1 - 0.00012 22.0 1.3 1.3 9.2 0.0 4.2 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN38041.1 - 0.027 14.9 0.1 16 6.0 0.0 3.7 3 0 0 3 3 3 0 HEAT repeats HEAT_EZ PF13513.6 RLN38041.1 - 0.029 14.9 0.6 0.99 10.0 0.1 3.0 2 0 0 2 2 2 0 HEAT-like repeat DUF5000 PF16391.5 RLN38041.1 - 0.75 9.9 2.4 1.8 8.7 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function Rota_NS6 PF04866.12 RLN38042.1 - 0.011 15.9 0.3 0.019 15.2 0.3 1.3 1 0 0 1 1 1 0 Rotavirus non-structural protein 6 PX PF00787.24 RLN38042.1 - 0.031 14.3 0.1 0.081 12.9 0.1 1.8 1 1 0 1 1 1 0 PX domain ATP_transf PF09830.9 RLN38043.1 - 1.5e-15 57.1 0.0 3e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase Cyclin_N PF00134.23 RLN38044.1 - 6.1e-14 51.9 0.3 1.6e-10 40.8 0.1 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 RLN38044.1 - 0.05 13.7 0.2 4.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Cyclin_C PF02984.19 RLN38044.1 - 0.087 12.9 0.1 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Cyclin, C-terminal domain tRNA_int_endo PF01974.17 RLN38045.1 - 8e-08 32.2 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Lipase_GDSL_2 PF13472.6 RLN38046.1 - 3.2e-10 40.7 0.0 3.6e-09 37.3 0.0 2.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family TPR_2 PF07719.17 RLN38046.1 - 1.9e-09 36.9 14.9 0.0048 16.9 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat Creatinase_N PF01321.18 RLN38046.1 - 3e-08 34.4 0.0 8.8e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain TPR_1 PF00515.28 RLN38046.1 - 4.7e-08 32.5 10.2 0.027 14.3 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN38046.1 - 2.5e-07 30.4 2.3 0.057 13.7 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat cNMP_binding PF00027.29 RLN38046.1 - 2.9e-07 30.5 0.0 0.12 12.5 0.0 3.9 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain TPR_11 PF13414.6 RLN38046.1 - 2.8e-05 23.7 0.4 0.0037 16.9 0.0 3.1 2 1 1 3 3 3 1 TPR repeat TPR_16 PF13432.6 RLN38046.1 - 0.00098 19.7 3.8 0.00098 19.7 3.8 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN38046.1 - 0.0017 18.6 12.8 0.27 11.5 4.6 3.6 2 1 0 3 3 3 1 Tetratricopeptide repeat Lipase_GDSL PF00657.22 RLN38046.1 - 0.0038 17.2 0.0 0.0065 16.5 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TPR_7 PF13176.6 RLN38046.1 - 0.0069 16.3 3.1 2.1 8.6 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN38046.1 - 0.013 16.2 12.7 0.024 15.4 2.8 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 RLN38046.1 - 0.029 14.7 3.6 4.3 7.9 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN38046.1 - 0.073 13.2 0.0 0.38 10.9 0.0 2.3 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat CE2_N PF17996.1 RLN38046.1 - 0.17 11.9 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Carbohydrate esterase 2 N-terminal TPR_19 PF14559.6 RLN38046.1 - 2.4 8.8 11.0 0.61 10.6 0.8 3.4 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN38046.1 - 3.4 7.7 9.8 41 4.2 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 RLN38046.1 - 6.8 6.9 11.1 1.6 8.9 2.7 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat Amino_oxidase PF01593.24 RLN38047.1 - 7.7e-68 229.8 0.1 3.4e-49 168.4 0.0 2.0 1 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RLN38047.1 - 8.1e-12 45.2 0.7 1.8e-11 44.1 0.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 RLN38047.1 - 3e-08 33.8 0.4 0.00089 19.3 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 RLN38047.1 - 8.3e-06 25.2 0.7 0.00036 19.9 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RLN38047.1 - 0.00017 20.8 2.9 0.048 12.7 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 RLN38047.1 - 0.00078 20.0 1.1 0.0091 16.5 1.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RLN38047.1 - 0.0014 18.2 9.5 0.012 15.2 9.5 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 RLN38047.1 - 0.004 16.5 1.2 0.0075 15.6 1.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 RLN38047.1 - 0.0088 15.4 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 RLN38047.1 - 0.014 14.6 0.2 2.3 7.4 0.5 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 RLN38047.1 - 0.016 14.4 0.4 0.03 13.6 0.4 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 RLN38047.1 - 0.022 13.5 1.5 0.24 10.1 0.6 2.1 2 0 0 2 2 2 0 HI0933-like protein MCRA PF06100.11 RLN38047.1 - 0.072 11.9 0.2 0.1 11.4 0.2 1.2 1 0 0 1 1 1 0 MCRA family FAD_binding_3 PF01494.19 RLN38047.1 - 0.2 10.9 1.2 0.37 10.0 1.0 1.5 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 RLN38047.1 - 0.23 10.5 6.0 0.25 10.4 4.1 1.8 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 RLN38047.1 - 0.61 8.9 3.9 0.42 9.4 1.2 1.9 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 RLN38047.1 - 1.1 8.3 4.4 0.36 9.8 1.6 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A AMP-binding PF00501.28 RLN38048.1 - 5.6e-80 269.0 0.0 1.2e-79 267.9 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN38048.1 - 1.8e-16 60.9 0.8 1.8e-16 60.9 0.8 2.4 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain bZIP_1 PF00170.21 RLN38049.1 - 0.17 12.0 0.2 0.17 12.0 0.2 6.5 6 1 0 6 6 6 0 bZIP transcription factor Phycobilisome PF00502.19 RLN38049.1 - 2.1 8.2 14.0 2.2 8.2 3.2 3.3 3 0 0 3 3 3 0 Phycobilisome protein Shugoshin_N PF07558.11 RLN38049.1 - 2.9 7.8 7.4 5.9 6.8 2.7 3.3 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Leu_zip PF15294.6 RLN38049.1 - 3.4 7.1 40.4 2.1 7.8 1.3 3.6 1 1 1 3 3 3 0 Leucine zipper Methyltransf_9 PF08003.11 RLN38049.1 - 7.8 5.3 8.5 1.1 8.2 3.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Nucleoside_tran PF01733.18 RLN38050.1 - 3.5e-28 98.9 2.0 5.3e-28 98.3 2.0 1.3 1 0 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 RLN38050.1 - 9.9e-05 21.4 10.8 9.9e-05 21.4 10.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3464 PF11947.8 RLN38050.1 - 4.2 7.1 6.0 0.83 9.4 1.6 2.1 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Mod_r PF07200.13 RLN38051.1 - 0.046 13.8 0.6 0.079 13.1 0.6 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein OKR_DC_1_C PF03711.15 RLN38051.1 - 0.074 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, C-terminal domain Cpn60_TCP1 PF00118.24 RLN38052.1 - 0.00044 19.0 0.0 0.00065 18.5 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peroxidase_2 PF01328.17 RLN38053.1 - 8.5e-54 182.9 0.0 1.1e-53 182.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 BT1 PF03092.16 RLN38054.1 - 3.5e-11 42.0 0.4 3.5e-11 42.0 0.4 3.7 4 1 1 5 5 5 2 BT1 family DUF3983 PF13137.6 RLN38054.1 - 0.12 12.2 0.6 0.22 11.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) MORN PF02493.20 RLN38055.1 - 9e-48 157.4 47.5 5e-08 32.4 0.2 10.2 10 0 0 10 10 10 9 MORN repeat Kelch_2 PF07646.15 RLN38055.1 - 2.7e-07 30.3 0.0 1.1 9.4 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 RLN38055.1 - 4.2e-07 29.9 7.6 1.1 9.3 0.0 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 RLN38055.1 - 1.1e-06 28.7 0.5 0.13 12.6 0.1 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 RLN38055.1 - 1.4e-05 24.9 1.8 0.29 11.2 0.3 4.6 5 1 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 RLN38055.1 - 0.0044 16.6 10.0 0.32 10.6 0.2 5.9 7 0 0 7 7 7 2 Kelch motif Med1 PF10744.9 RLN38055.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 Sybindin PF04099.12 RLN38056.1 - 6.3e-41 139.6 0.1 4.7e-31 107.6 0.0 2.0 2 0 0 2 2 2 2 Sybindin-like family Sedlin_N PF04628.13 RLN38056.1 - 0.013 15.6 0.0 1.1 9.3 0.0 2.3 2 1 0 2 2 2 0 Sedlin, N-terminal conserved region Mito_carr PF00153.27 RLN38102.1 - 5.8e-31 106.3 0.1 4.2e-10 39.4 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2353 PF09789.9 RLN38103.1 - 0.00013 21.5 29.4 0.0024 17.3 29.7 2.3 1 1 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) SCAB-Ig PF16709.5 RLN38103.1 - 0.024 14.7 0.0 0.068 13.2 0.0 1.8 1 0 0 1 1 1 0 Ig domain of plant-specific actin-binding protein PDZ PF00595.24 RLN38103.1 - 0.073 13.4 0.1 2.2 8.7 0.0 2.8 2 0 0 2 2 2 0 PDZ domain TPR_MLP1_2 PF07926.12 RLN38103.1 - 0.77 9.8 38.9 0.56 10.3 15.1 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein NRBF2 PF08961.10 RLN38103.1 - 0.87 9.2 21.0 0.04 13.5 6.1 2.8 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Vps5 PF09325.10 RLN38103.1 - 9.4 5.7 22.5 8.2 5.9 5.6 3.0 2 1 1 3 3 3 0 Vps5 C terminal like Utp21 PF04192.12 RLN38104.1 - 1.8e-51 174.9 2.4 3.6e-51 173.9 2.4 1.4 1 1 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 RLN38104.1 - 1.2e-13 51.2 3.2 3.5e-06 27.7 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN38104.1 - 4.8e-07 30.0 0.0 0.00025 21.3 0.0 3.4 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN38104.1 - 0.00023 19.9 1.0 0.23 10.1 0.2 2.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 RLN38104.1 - 0.028 13.0 0.0 0.094 11.2 0.0 1.7 1 1 1 2 2 2 0 Cytochrome D1 heme domain Utp12 PF04003.12 RLN38104.1 - 0.66 10.3 3.4 1.2 9.5 3.4 1.4 1 0 0 1 1 1 0 Dip2/Utp12 Family FMN_red PF03358.15 RLN38118.1 - 3.8e-13 49.5 0.0 4.8e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 RLN38118.1 - 1.8e-06 27.8 0.0 2.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 RLN38118.1 - 0.00017 21.8 0.1 0.00031 21.0 0.1 1.4 1 1 0 1 1 1 1 Flavodoxin DAGK_acc PF00609.19 RLN38119.1 - 1.6e-52 178.0 0.0 2.9e-52 177.2 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 RLN38119.1 - 5.9e-25 87.3 0.0 1.2e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 RLN38119.1 - 8.6e-18 64.0 13.4 3.4e-10 39.6 5.1 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 RLN38119.1 - 0.00082 19.2 11.3 0.0057 16.5 0.6 2.5 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 RLN38119.1 - 0.0041 16.6 7.0 0.24 11.0 1.0 2.9 2 0 0 2 2 2 2 PHD-finger C1_2 PF03107.16 RLN38119.1 - 0.027 14.8 12.4 0.035 14.4 2.3 2.5 2 0 0 2 2 2 0 C1 domain zf-RING-like PF08746.11 RLN38119.1 - 0.14 12.5 14.5 0.16 12.3 4.9 2.5 2 0 0 2 2 2 0 RING-like domain Zf_RING PF16744.5 RLN38119.1 - 0.28 11.3 8.6 1.7 8.8 1.3 2.4 2 0 0 2 2 2 0 KIAA1045 RING finger PHD_4 PF16866.5 RLN38119.1 - 0.4 10.8 7.0 5.4 7.2 1.3 2.8 2 1 0 2 2 2 0 PHD-finger Zn_ribbon_17 PF17120.5 RLN38119.1 - 0.52 10.0 10.3 0.35 10.5 0.7 2.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type MORN PF02493.20 RLN38120.1 - 7.9e-15 53.8 28.9 6e-07 29.0 1.8 5.2 6 0 0 6 6 6 3 MORN repeat DSPc PF00782.20 RLN38121.1 - 1.6e-30 105.6 0.2 2.8e-30 104.8 0.2 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 RLN38121.1 - 2.2e-06 28.1 0.0 1.1e-05 25.8 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 RLN38121.1 - 9e-05 22.1 0.1 0.00015 21.5 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 RLN38121.1 - 0.0011 19.2 0.0 0.002 18.3 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate PCRF PF03462.18 RLN38122.1 - 4.2e-51 173.6 0.3 6.9e-51 172.9 0.3 1.3 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 RLN38122.1 - 3.5e-38 130.1 0.1 8.8e-38 128.8 0.1 1.7 1 0 0 1 1 1 1 RF-1 domain LRR_6 PF13516.6 RLN38123.1 - 4.4e-22 76.2 16.7 0.0051 16.8 0.0 9.3 9 0 0 9 9 9 5 Leucine Rich repeat LRR_1 PF00560.33 RLN38123.1 - 0.0027 18.0 8.9 4.3 8.3 0.1 6.9 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_8 PF13855.6 RLN38123.1 - 0.0051 16.5 18.7 9.1 6.1 0.0 7.4 4 1 4 8 8 8 3 Leucine rich repeat LRR_4 PF12799.7 RLN38123.1 - 0.0056 17.1 18.1 1 9.9 0.9 6.2 4 2 3 7 7 7 4 Leucine Rich repeats (2 copies) VID27_N PF17748.1 RLN38123.1 - 0.071 12.9 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 VID27 N-terminal region COPI_assoc PF08507.10 RLN38124.1 - 8.4e-18 64.7 7.3 1.2e-17 64.2 7.3 1.2 1 0 0 1 1 1 1 COPI associated protein KdpC PF02669.15 RLN38124.1 - 2.2 8.1 6.7 13 5.6 0.5 2.2 2 0 0 2 2 2 0 K+-transporting ATPase, c chain Mito_carr PF00153.27 RLN38125.1 - 4.1e-43 145.2 0.7 9.9e-19 67.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 RLN38125.1 - 0.0049 16.1 0.0 0.21 10.7 0.0 2.4 1 1 1 2 2 2 2 Gammaproteobacterial serine protease FYVE PF01363.21 RLN38127.1 - 1.9e-06 27.9 10.3 4.4e-06 26.7 10.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN38127.1 - 0.34 11.1 6.4 0.73 10.1 6.4 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Na_Ca_ex PF01699.24 RLN38128.1 - 1.7e-37 128.7 38.4 3.2e-20 72.6 17.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Trehalose_PPase PF02358.16 RLN38129.1 - 5.5e-54 182.8 0.0 6.7e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 RLN38129.1 - 0.00039 20.2 0.0 0.048 13.4 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase ETC_C1_NDUFA4 PF04800.12 RLN38130.1 - 8.4e-29 99.7 0.1 1.7e-28 98.7 0.1 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region OrfB_Zn_ribbon PF07282.11 RLN38133.1 - 1.7e-08 34.3 2.1 5.9e-08 32.5 2.1 1.9 1 1 0 1 1 1 1 Putative transposase DNA-binding domain Atg14 PF10186.9 RLN38138.1 - 0.47 9.5 6.2 0.75 8.8 6.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PH PF00169.29 RLN38142.1 - 4e-12 46.6 0.0 7.5e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN38142.1 - 0.00067 19.9 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 RLN38142.1 - 0.00079 19.5 0.0 0.013 15.5 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 RLN38142.1 - 0.024 15.0 0.4 0.15 12.5 0.4 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain Guanylate_cyc PF00211.20 RLN38143.1 - 4.2e-97 323.1 0.4 4.4e-51 173.1 0.1 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain PUB PF09409.10 RLN38143.1 - 1e-39 134.3 0.0 5.4e-13 48.7 0.0 5.2 5 0 0 5 5 5 4 PUB domain TUDOR_5 PF18359.1 RLN38143.1 - 1.2e-28 98.6 51.9 0.00021 20.9 0.4 11.6 12 0 0 12 12 12 10 Histone methyltransferase Tudor domain 1 DUF1325 PF07039.11 RLN38143.1 - 1.2e-26 93.4 6.3 0.0045 17.1 0.1 10.8 6 2 5 11 11 10 6 SGF29 tudor-like domain Agenet PF05641.12 RLN38143.1 - 1e-20 74.0 31.3 0.055 13.9 0.0 14.0 14 0 0 14 14 13 5 Agenet domain LBR_tudor PF09465.10 RLN38143.1 - 2.4e-19 68.9 30.6 0.0015 18.3 0.3 11.5 11 0 0 11 11 11 6 Lamin-B receptor of TUDOR domain DUF4537 PF15057.6 RLN38143.1 - 4.2e-19 68.8 12.1 0.00028 20.9 0.1 9.8 8 2 3 11 11 11 4 Domain of unknown function (DUF4537) 53-BP1_Tudor PF09038.10 RLN38143.1 - 4.7e-13 49.2 32.4 0.55 10.2 0.1 11.8 12 1 1 13 13 12 4 Tumour suppressor p53-binding protein-1 Tudor TUDOR PF00567.24 RLN38143.1 - 6.2e-09 35.9 3.3 0.097 12.7 0.0 8.1 7 3 3 10 10 9 2 Tudor domain TTD PF12148.8 RLN38143.1 - 2.1e-06 27.7 8.3 0.29 11.0 0.3 6.4 5 1 1 6 6 6 1 Tandem tudor domain within UHRF1 Tudor_2 PF18104.1 RLN38143.1 - 9.1e-06 25.3 42.3 0.0031 17.1 0.2 9.9 11 0 0 11 11 11 4 Jumonji domain-containing protein 2A Tudor domain EF-hand_6 PF13405.6 RLN38143.1 - 0.0008 19.2 4.8 0.29 11.2 0.1 4.9 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 RLN38143.1 - 0.0012 19.2 2.1 0.034 14.6 0.1 3.7 3 1 0 3 3 3 1 EF-hand domain pair DUF150_C PF17384.2 RLN38143.1 - 0.14 12.3 20.3 9.7 6.4 0.3 7.6 7 0 0 7 7 7 0 RimP C-terminal SH3 domain HNOBA PF07701.14 RLN38143.1 - 0.28 10.6 4.2 1.8 7.9 0.5 2.6 2 0 0 2 2 2 0 Heme NO binding associated EF-hand_8 PF13833.6 RLN38143.1 - 0.31 10.9 2.1 1.9 8.4 0.4 3.1 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.32 RLN38143.1 - 1.9 8.2 12.6 0.31 10.7 0.1 4.8 5 0 0 5 5 5 0 EF hand NHase_beta PF02211.15 RLN38143.1 - 7 6.6 11.8 59 3.6 0.1 5.4 4 1 0 5 5 5 0 Nitrile hydratase beta subunit EF-hand_7 PF13499.6 RLN38144.1 - 2.3e-07 31.1 0.1 5.7e-06 26.7 0.1 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN38144.1 - 4.4e-05 22.7 0.0 0.00019 20.8 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RLN38144.1 - 5.7e-05 22.7 0.0 0.00053 19.7 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 RLN38144.1 - 0.0016 17.9 0.0 0.0072 15.8 0.0 2.3 2 0 0 2 2 2 1 EF hand 6PF2K PF01591.18 RLN38145.1 - 1.9e-16 60.1 0.0 2.5e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AMPK1_CBM PF16561.5 RLN38145.1 - 2.5e-13 50.0 0.0 5.4e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase APS_kinase PF01583.20 RLN38145.1 - 0.097 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.6 RLN38145.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 RLN38145.1 - 0.18 11.9 0.1 0.31 11.1 0.1 1.3 1 0 0 1 1 1 0 Torsin EF-hand_7 PF13499.6 RLN38146.1 - 0.00027 21.3 0.1 0.00045 20.6 0.1 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN38146.1 - 0.038 13.9 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 EF-hand domain DUF659 PF04937.15 RLN38147.1 - 6.6e-31 107.2 0.2 1.2e-30 106.4 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 RLN38147.1 - 1.7e-11 43.8 0.0 4e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 RLN38147.1 - 0.0042 17.1 0.2 0.01 15.8 0.2 1.7 1 0 0 1 1 1 1 BED zinc finger DUF1244 PF06844.11 RLN38147.1 - 0.066 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) RrnaAD PF00398.20 RLN38149.1 - 6.4e-58 195.9 0.0 1.1e-57 195.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 RLN38149.1 - 9.3e-09 35.9 0.1 4e-08 33.9 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN38149.1 - 1.3e-08 35.4 0.0 2.2e-07 31.4 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN38149.1 - 0.00023 21.9 0.0 0.00095 19.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 RLN38149.1 - 0.00045 19.7 0.0 0.0013 18.3 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase NodS PF05401.11 RLN38149.1 - 0.00061 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_23 PF13489.6 RLN38149.1 - 0.00083 19.2 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 RLN38149.1 - 0.0013 18.5 0.1 0.0025 17.6 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 RLN38149.1 - 0.0037 16.6 0.0 0.0069 15.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PRMT5 PF05185.16 RLN38149.1 - 0.0047 16.8 0.1 0.02 14.8 0.0 2.0 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.16 RLN38149.1 - 0.0048 16.7 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 RLN38149.1 - 0.01 15.5 0.0 0.032 13.9 0.0 1.8 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 MTS PF05175.14 RLN38149.1 - 0.021 14.4 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.15 RLN38149.1 - 0.028 14.0 0.0 0.097 12.3 0.0 1.9 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_28 PF02636.17 RLN38149.1 - 0.053 13.2 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 RLN38149.1 - 0.11 11.8 0.0 0.31 10.3 0.0 1.6 1 0 0 1 1 1 0 O-methyltransferase domain Phage_GP20 PF06810.11 RLN38149.1 - 0.29 10.9 0.1 0.29 10.9 0.1 4.2 3 1 1 4 4 4 0 Phage minor structural protein GP20 zf-C3HC4_3 PF13920.6 RLN38181.1 - 3.2e-11 42.9 6.5 6.2e-11 42.0 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN38181.1 - 4.8e-11 42.8 10.7 8.4e-11 42.0 10.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 RLN38181.1 - 2.2e-09 37.2 6.3 4.1e-09 36.3 6.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RLN38181.1 - 3.3e-09 36.4 9.8 6e-09 35.6 9.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN38181.1 - 7.8e-09 35.3 9.4 1.4e-08 34.4 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN38181.1 - 2.1e-08 33.9 6.8 4.3e-08 32.9 6.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN38181.1 - 8.2e-08 32.1 7.4 1.4e-07 31.3 7.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 RLN38181.1 - 2.5e-05 24.5 8.6 7.8e-05 22.9 8.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 RLN38181.1 - 3.2e-05 24.0 10.5 6.2e-05 23.1 10.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING U-box PF04564.15 RLN38181.1 - 0.00037 20.6 0.0 0.00078 19.6 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-RING_6 PF14835.6 RLN38181.1 - 0.0006 19.6 5.2 0.0012 18.7 5.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 RLN38181.1 - 0.0084 15.8 5.4 0.0084 15.8 5.4 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 RLN38181.1 - 0.015 15.3 2.1 0.038 14.0 2.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 RLN38181.1 - 0.035 13.7 4.5 0.068 12.8 4.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 RLN38181.1 - 0.12 12.2 4.2 0.22 11.4 4.2 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 RLN38181.1 - 1 9.5 5.5 2.1 8.6 5.5 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 SRRM_C PF15230.6 RLN38181.1 - 3.6 8.2 10.4 0.52 10.9 5.9 1.8 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus NST1 PF13945.6 RLN38182.1 - 0.21 11.7 0.3 0.41 10.7 0.3 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator Mito_carr PF00153.27 RLN38183.1 - 4.3e-18 65.0 0.9 7.6e-14 51.4 0.1 2.5 2 1 0 2 2 2 2 Mitochondrial carrier protein PFU PF09070.11 RLN38202.1 - 4.5e-07 30.1 0.1 6.9e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 PFU (PLAA family ubiquitin binding) SUIM_assoc PF16619.5 RLN38202.1 - 0.046 13.8 6.1 0.47 10.6 1.1 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ROS_MUCR PF05443.11 RLN38202.1 - 0.25 11.4 3.3 22 5.1 0.0 2.8 3 0 0 3 3 3 0 ROS/MUCR transcriptional regulator protein CNOT1_HEAT PF16418.5 RLN38202.1 - 0.68 10.0 4.6 0.94 9.5 0.2 2.2 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat SPRY PF00622.28 RLN38203.1 - 2.6e-05 24.3 0.2 0.0011 19.0 0.0 3.3 3 1 0 3 3 3 1 SPRY domain Ribosomal_60s PF00428.19 RLN38203.1 - 0.06 13.9 9.8 0.92 10.1 0.4 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein RPA43_OB PF17875.1 RLN38203.1 - 0.09 13.4 0.0 0.21 12.2 0.0 1.6 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I KIX_2 PF16987.5 RLN38204.1 - 0.00019 21.4 0.0 0.00019 21.4 0.0 2.2 2 0 0 2 2 2 1 KIX domain DUF1041 PF06292.17 RLN38204.1 - 0.013 15.9 0.6 0.013 15.9 0.6 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) HTH_32 PF13565.6 RLN38227.1 - 0.13 12.8 0.3 2.6 8.7 0.1 2.5 2 0 0 2 2 2 0 Homeodomain-like domain MgtE_N PF03448.17 RLN38227.1 - 0.14 12.8 0.9 0.48 11.0 1.3 1.6 2 0 0 2 2 2 0 MgtE intracellular N domain EnY2 PF10163.9 RLN38227.1 - 0.23 11.9 1.2 1.9 8.9 1.2 2.3 1 1 0 1 1 1 0 Transcription factor e(y)2 DHHC PF01529.20 RLN38228.1 - 1.2e-24 86.9 24.9 3.7e-19 69.1 0.8 3.1 3 0 0 3 3 3 2 DHHC palmitoyltransferase SelR PF01641.18 RLN38229.1 - 7.7e-10 38.9 1.0 8.5e-10 38.8 1.0 1.1 1 0 0 1 1 1 1 SelR domain PUB PF09409.10 RLN38230.1 - 2.6e-16 59.3 0.1 9.4e-16 57.5 0.0 2.0 2 0 0 2 2 2 1 PUB domain Thioredoxin PF00085.20 RLN38230.1 - 2.7e-09 36.9 0.0 1.8e-07 31.1 0.0 2.8 1 1 0 1 1 1 1 Thioredoxin UBA PF00627.31 RLN38230.1 - 1.1e-07 31.6 0.1 2.5e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Macoilin PF09726.9 RLN38230.1 - 0.16 10.5 8.1 0.2 10.1 8.1 1.2 1 0 0 1 1 1 0 Macoilin family Thioredoxin_2 PF13098.6 RLN38230.1 - 0.45 11.0 1.8 0.84 10.1 0.0 2.4 3 1 0 3 3 3 0 Thioredoxin-like domain Atg14 PF10186.9 RLN38230.1 - 2.1 7.3 7.8 3.6 6.6 7.8 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fungal_TACC PF12709.7 RLN38230.1 - 2.5 8.6 12.2 1.7 9.1 3.7 3.5 3 1 1 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF724 PF05266.14 RLN38230.1 - 6.3 6.6 13.2 14 5.5 13.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Tubulin PF00091.25 RLN38231.1 - 2.4e-33 116.0 0.2 4.1e-33 115.2 0.2 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 RLN38231.1 - 8.6e-28 96.5 0.2 2.3e-27 95.1 0.2 1.8 1 0 0 1 1 1 1 FtsZ family, C-terminal domain Ank_4 PF13637.6 RLN38231.1 - 9.2e-11 42.1 0.2 6.5e-06 26.6 0.2 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN38231.1 - 9.9e-10 38.9 0.4 0.0013 19.3 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN38231.1 - 3.3e-06 27.3 0.8 0.014 15.7 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN38231.1 - 2.9e-05 24.3 1.6 0.1 13.1 0.1 4.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 RLN38231.1 - 3.4e-05 23.9 0.6 0.05 14.2 0.1 4.3 4 0 0 4 4 4 1 Ankyrin repeat PDZ_6 PF17820.1 RLN38231.1 - 0.14 12.0 1.8 0.36 10.7 0.1 2.7 3 0 0 3 3 3 0 PDZ domain SRP54 PF00448.22 RLN38232.1 - 1.8e-75 252.9 0.1 3.5e-75 251.9 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 RLN38232.1 - 3.8e-28 98.0 1.0 3.8e-28 98.0 1.0 3.4 3 0 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 RLN38232.1 - 6.2e-18 64.8 2.5 1.2e-17 63.8 2.5 1.5 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain SRPRB PF09439.10 RLN38232.1 - 5.6e-05 22.6 1.0 0.6 9.5 0.0 3.7 2 2 1 3 3 3 2 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 RLN38232.1 - 6.1e-05 23.5 0.0 0.00019 21.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 RLN38232.1 - 9.2e-05 22.6 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 RLN38232.1 - 0.00047 19.8 0.2 0.0071 16.0 0.2 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 RLN38232.1 - 0.00074 19.3 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 RLN38232.1 - 0.0014 17.7 0.0 0.013 14.5 0.0 2.4 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2209 PF09974.9 RLN38232.1 - 0.0017 18.7 0.1 0.0039 17.5 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) AAA_22 PF13401.6 RLN38232.1 - 0.015 15.6 0.0 0.044 14.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 RLN38232.1 - 0.024 14.5 0.0 0.088 12.7 0.0 2.0 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MMR_HSR1 PF01926.23 RLN38232.1 - 0.032 14.3 0.2 0.6 10.2 0.2 2.9 2 2 1 3 3 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 RLN38232.1 - 0.033 14.4 0.0 0.072 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 RLN38232.1 - 0.034 14.0 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase MobB PF03205.14 RLN38232.1 - 0.042 13.8 0.0 0.098 12.6 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.23 RLN38232.1 - 0.048 13.7 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.6 RLN38232.1 - 0.072 13.4 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 RLN38232.1 - 0.074 13.5 0.2 0.43 11.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 RLN38232.1 - 0.09 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SelR PF01641.18 RLN38233.1 - 1.3e-28 99.5 0.1 1.6e-28 99.2 0.1 1.1 1 0 0 1 1 1 1 SelR domain Pkinase_Tyr PF07714.17 RLN38235.1 - 3.1e-15 56.2 0.0 6.6e-15 55.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN38235.1 - 2.8e-13 49.8 0.0 4.2e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 RLN38235.1 - 0.034 13.5 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 RLN38257.1 - 4.9e-06 27.2 1.8 1.6 9.7 0.0 5.1 6 0 0 6 6 6 2 WD domain, G-beta repeat Abhydrolase_3 PF07859.13 RLN38257.1 - 0.17 11.7 1.8 1.1 9.0 0.3 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Pkinase PF00069.25 RLN38258.1 - 5.8e-49 166.8 0.0 8.8e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN38258.1 - 1.3e-43 149.2 0.0 1.8e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NUDIX_5 PF16705.5 RLN38258.1 - 0.0063 16.3 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX, or N-terminal NPxY motif-rich, region of KRIT Kdo PF06293.14 RLN38258.1 - 0.14 11.4 0.1 0.36 10.1 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Y_phosphatase2 PF03162.13 RLN38259.1 - 5.4e-40 136.7 0.5 3.6e-18 65.7 0.1 3.0 2 1 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 RLN38259.1 - 0.025 14.6 0.0 0.086 12.8 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family Pkinase PF00069.25 RLN38260.1 - 8.2e-50 169.6 0.0 1.7e-49 168.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN38260.1 - 1.1e-45 156.0 0.0 1.4e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase VSP PF03302.13 RLN38260.1 - 0.0036 16.2 22.4 0.0036 16.2 22.4 2.2 1 1 1 2 2 2 1 Giardia variant-specific surface protein PTP_tm PF18861.1 RLN38260.1 - 0.0067 16.4 0.3 0.012 15.6 0.3 1.3 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Podoplanin PF05808.11 RLN38260.1 - 0.023 14.8 23.5 0.041 14.0 21.8 2.4 1 1 1 2 2 2 0 Podoplanin Pkinase_fungal PF17667.1 RLN38260.1 - 0.18 10.6 0.6 0.49 9.1 0.1 1.8 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 RLN38260.1 - 0.23 10.4 0.0 0.4 9.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain SPX PF03105.19 RLN38260.1 - 0.41 10.5 2.9 0.64 9.9 2.9 1.3 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 RLN38260.1 - 1.6 7.9 10.4 2.2 7.4 10.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein PsbX PF06596.11 RLN38260.1 - 2 8.5 6.5 4.1 7.5 6.5 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) Apt1 PF10351.9 RLN38260.1 - 2.2 7.0 5.4 3.2 6.5 5.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 RLN38260.1 - 7.9 4.9 6.0 10 4.5 6.0 1.2 1 0 0 1 1 1 0 Macoilin family NADH_4Fe-4S PF10589.9 RLN38261.1 - 1.9e-15 56.7 0.0 2.4e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Exonuc_VII_S PF02609.16 RLN38261.1 - 0.45 10.6 3.0 1.3 9.1 0.4 2.4 2 1 1 3 3 3 0 Exonuclease VII small subunit PIP5K PF01504.18 RLN38263.1 - 9.7e-63 211.9 0.0 5e-61 206.3 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase NMN_transporter PF04973.12 RLN38263.1 - 0.0002 21.4 1.0 0.0002 21.4 1.0 2.0 2 0 0 2 2 2 1 Nicotinamide mononucleotide transporter CcmF_C PF16327.5 RLN38263.1 - 0.018 14.3 0.5 0.029 13.7 0.5 1.2 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal DUF3974 PF13120.6 RLN38263.1 - 0.067 13.3 0.2 0.19 11.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) Frizzled PF01534.17 RLN38263.1 - 1.1 8.2 8.3 3.1 6.7 8.3 1.6 1 1 0 1 1 1 0 Frizzled/Smoothened family membrane region SPX PF03105.19 RLN38266.1 - 3.2e-24 86.6 14.0 1.4e-12 48.3 2.3 3.3 1 1 2 3 3 3 3 SPX domain Ank_2 PF12796.7 RLN38268.1 - 2.2e-24 85.8 4.6 5.7e-13 49.3 0.1 3.4 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN38268.1 - 6.1e-22 77.7 2.7 3.6e-10 40.2 0.0 5.5 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN38268.1 - 6.2e-22 77.4 0.5 4.1e-08 33.3 0.1 4.4 2 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN38268.1 - 6.5e-21 73.8 3.0 5.9e-06 26.5 0.1 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 RLN38268.1 - 2.2e-17 61.4 2.1 0.00054 20.2 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat HECT PF00632.25 RLN38269.1 - 8.6e-45 153.5 0.0 4.7e-40 138.0 0.0 2.1 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) tRNA_m1G_MT PF01746.21 RLN38270.1 - 1.2e-14 54.5 0.0 1.8e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DUF3824 PF12868.7 RLN38270.1 - 0.052 14.2 3.2 0.052 14.2 3.2 2.2 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) GlcNAc PF11397.8 RLN38271.1 - 4.3e-53 181.0 2.2 1.3e-50 172.9 1.0 2.1 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Glycos_transf_2 PF00535.26 RLN38271.1 - 0.092 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 ADP_ribosyl_GH PF03747.14 RLN38272.1 - 1.7e-30 106.8 2.6 1.9e-30 106.6 2.6 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Kelch_4 PF13418.6 RLN38275.1 - 1.4e-41 140.2 3.1 2.2e-07 30.8 0.0 7.1 5 2 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 RLN38275.1 - 1.2e-35 121.1 4.3 1.6e-08 34.6 0.0 7.8 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN38275.1 - 7.4e-32 108.8 1.5 0.00015 21.6 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RLN38275.1 - 7.3e-30 102.3 0.3 1.5e-08 34.6 0.0 5.7 5 1 1 6 6 6 5 Kelch motif DUF4110 PF13422.6 RLN38275.1 - 1.6e-28 98.6 1.3 1.6e-28 98.6 1.3 4.3 4 1 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_1 PF01344.25 RLN38275.1 - 2.9e-22 78.0 3.4 5.5e-05 22.7 0.0 6.5 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 RLN38275.1 - 6.4e-19 67.1 4.3 6e-05 22.9 0.0 6.5 6 1 0 6 6 6 3 Kelch motif FYVE PF01363.21 RLN38277.1 - 3e-05 24.1 10.5 8.6e-05 22.6 10.5 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN38277.1 - 0.00011 22.4 6.9 0.00021 21.5 6.9 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger Spore_SspJ PF09575.10 RLN38277.1 - 0.23 11.9 0.0 12 6.4 0.0 2.5 2 0 0 2 2 2 0 Small spore protein J (Spore_SspJ) C1_2 PF03107.16 RLN38277.1 - 0.35 11.2 4.3 0.93 9.9 4.3 1.7 1 0 0 1 1 1 0 C1 domain Endonuclease_7 PF02945.15 RLN38277.1 - 0.71 9.8 6.5 5.6 7.0 0.1 2.7 2 0 0 2 2 2 0 Recombination endonuclease VII zf-B_box PF00643.24 RLN38277.1 - 0.73 10.0 10.1 0.083 13.1 5.6 1.8 2 0 0 2 2 2 0 B-box zinc finger zf-UDP PF14569.6 RLN38277.1 - 1.1 9.4 3.4 2.6 8.2 3.4 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger RCC1 PF00415.18 RLN38278.1 - 9.2e-57 189.5 28.9 1.2e-12 48.2 0.3 7.9 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN38278.1 - 5.9e-38 127.9 43.4 8.3e-10 38.2 1.2 9.2 9 0 0 9 9 9 7 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 RLN38278.1 - 1.6e-19 70.2 0.0 6.7e-11 42.4 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain AAA_19 PF13245.6 RLN38278.1 - 0.16 12.3 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 RLN38279.1 - 6.1e-73 246.1 0.0 8.1e-73 245.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Strumpellin PF10266.9 RLN38279.1 - 0.092 10.4 0.0 0.13 10.0 0.0 1.1 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin Chorismate_synt PF01264.21 RLN38292.1 - 4.7e-53 180.0 0.1 5.3e-53 179.8 0.1 1.0 1 0 0 1 1 1 1 Chorismate synthase SAC3_GANP PF03399.16 RLN38293.1 - 1.4e-21 77.1 1.1 6.9e-20 71.6 1.1 2.2 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 RLN38293.1 - 0.0026 17.8 0.0 0.028 14.4 0.0 2.4 2 1 0 3 3 3 1 CSN8/PSMD8/EIF3K family Glutaredoxin PF00462.24 RLN38294.1 - 8.8e-21 73.9 0.0 1.6e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GREB1 PF15782.5 RLN38294.1 - 0.018 12.2 0.0 0.02 12.0 0.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SH3BGR PF04908.15 RLN38294.1 - 0.019 15.1 0.0 0.059 13.5 0.0 1.7 1 1 0 1 1 1 0 SH3-binding, glutamic acid-rich protein GST_N_3 PF13417.6 RLN38294.1 - 0.17 12.3 0.0 0.42 11.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF2052 PF09747.9 RLN38295.1 - 3.4e-32 112.2 21.1 6.7e-32 111.2 21.1 1.5 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) OspD PF03207.13 RLN38295.1 - 0.19 11.1 0.8 0.28 10.5 0.8 1.2 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) IQ PF00612.27 RLN38296.1 - 0.0005 19.6 0.4 0.0013 18.4 0.4 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Pkinase PF00069.25 RLN38326.1 - 3.5e-46 157.7 0.0 5e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN38326.1 - 2.5e-39 135.1 0.0 3.9e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN38326.1 - 0.025 13.4 0.1 0.038 12.8 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 RLN38326.1 - 0.028 13.8 0.1 0.042 13.2 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN38326.1 - 0.063 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN38326.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DZR PF12773.7 RLN38327.1 - 0.0026 17.7 35.5 0.34 11.0 3.1 4.3 4 0 0 4 4 4 4 Double zinc ribbon zf-CCHC_6 PF15288.6 RLN38327.1 - 0.057 13.3 32.3 0.7 9.8 5.1 5.1 4 1 1 5 5 5 0 Zinc knuckle zf-CCHC_2 PF13696.6 RLN38327.1 - 0.1 12.5 35.5 1 9.2 4.5 5.6 5 0 0 5 5 5 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 RLN38327.1 - 0.9 9.9 27.2 1.7 9.0 9.3 4.1 3 1 0 3 3 3 0 DnaJ central domain WD40 PF00400.32 RLN38328.1 - 4.2e-33 112.8 24.0 5.1e-10 39.8 0.7 7.5 6 2 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN38328.1 - 2e-15 56.9 3.1 0.0077 16.5 0.0 5.7 4 2 1 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RLN38328.1 - 1.9e-05 24.7 0.2 0.29 11.0 0.0 3.8 3 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 RLN38328.1 - 0.001 18.9 2.5 0.018 15.0 0.1 2.6 2 0 0 2 2 2 1 LisH Nup160 PF11715.8 RLN38328.1 - 0.01 14.5 2.6 1.5 7.3 0.0 3.9 4 1 1 5 5 5 0 Nucleoporin Nup120/160 TPR_2 PF07719.17 RLN38329.1 - 3.5e-07 29.8 4.5 0.094 12.9 0.3 4.7 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN38329.1 - 5.2e-06 26.0 0.2 5e-05 22.9 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.28 RLN38329.1 - 1.2e-05 24.9 3.5 0.4 10.6 0.3 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN38329.1 - 1.5e-05 24.8 5.0 0.023 14.9 0.0 4.9 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN38329.1 - 2.1e-05 24.6 0.5 0.00098 19.4 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN38329.1 - 0.00048 20.7 0.6 5.6 8.0 0.0 3.7 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN38329.1 - 0.00054 20.2 2.2 0.057 13.7 0.6 3.9 2 2 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN38329.1 - 0.0014 18.8 0.5 0.22 11.7 0.3 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 RLN38329.1 - 0.0017 18.9 1.0 1.3 9.5 1.2 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat BfiI_DBD PF18243.1 RLN38330.1 - 0.019 14.6 0.1 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 Metal-independent restriction enzyme BfiI DNA binding domain TIR_2 PF13676.6 RLN38331.1 - 3.5e-13 50.2 0.0 1.9e-08 34.9 0.0 3.1 2 1 0 2 2 2 2 TIR domain AAA_16 PF13191.6 RLN38331.1 - 0.0025 18.2 0.0 0.0056 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain PALP PF00291.25 RLN38332.1 - 8.9e-52 176.3 5.6 3.9e-51 174.2 2.4 2.6 2 1 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme DnaJ PF00226.31 RLN38333.1 - 1.6e-10 41.0 0.0 1.2e-09 38.1 0.0 2.4 2 1 0 2 2 2 1 DnaJ domain PPP4R2 PF09184.11 RLN38348.1 - 1.7e-17 64.0 0.0 2.1e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 PPP4R2 CEP76-C2 PF15627.6 RLN38349.1 - 2.9e-41 140.7 0.0 4.7e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 CEP76 C2 domain cNMP_binding PF00027.29 RLN38350.1 - 1.7e-12 47.2 0.1 1.1e-11 44.6 0.0 2.5 3 0 0 3 3 3 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN38350.1 - 7.4e-11 41.7 5.4 1.3e-10 41.0 5.4 1.4 1 1 0 1 1 1 1 Ion transport protein DUF5336 PF17270.2 RLN38351.1 - 0.023 14.3 0.4 0.09 12.4 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5336) HTH_Crp_2 PF13545.6 RLN38351.1 - 0.038 14.0 0.4 0.076 13.0 0.4 1.7 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain IF2_N PF04760.15 RLN38352.1 - 0.18 11.7 0.2 0.61 9.9 0.1 2.0 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region COesterase PF00135.28 RLN38353.1 - 2.5e-87 293.9 0.1 5.3e-87 292.8 0.1 1.5 1 0 0 1 1 1 1 Carboxylesterase family DHR-2 PF06920.13 RLN38353.1 - 0.00053 18.8 1.4 0.00086 18.1 1.4 1.2 1 0 0 1 1 1 1 Dock homology region 2 Abhydrolase_3 PF07859.13 RLN38353.1 - 0.015 15.2 0.8 0.12 12.2 0.0 2.7 3 0 0 3 3 3 0 alpha/beta hydrolase fold TPR_10 PF13374.6 RLN38353.1 - 0.72 9.8 6.2 9.1 6.3 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat LysM PF01476.20 RLN38354.1 - 0.012 15.6 0.0 15 5.8 0.0 3.4 3 0 0 3 3 3 0 LysM domain WD40 PF00400.32 RLN38355.1 - 4.7e-20 71.5 0.1 0.0021 18.9 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN38355.1 - 2.2e-07 31.1 0.0 0.43 10.9 0.0 4.3 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DASH_Dad2 PF08654.10 RLN38370.1 - 0.032 14.6 0.1 0.067 13.6 0.1 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad2 Sugar_tr PF00083.24 RLN38372.1 - 4.2e-97 325.9 18.5 4.9e-97 325.6 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN38372.1 - 2.6e-27 95.7 29.8 2.6e-23 82.5 27.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CytB6-F_Fe-S PF08802.10 RLN38372.1 - 0.71 9.9 8.2 2.6 8.2 0.2 3.1 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit DUF2583 PF10762.9 RLN38372.1 - 1.2 9.6 8.7 1.1 9.7 4.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) DnaJ_C PF01556.18 RLN38373.1 - 5.6e-29 101.1 0.0 7.5e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RLN38373.1 - 8.6e-23 80.2 0.5 1.4e-22 79.5 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 RLN38373.1 - 2.3e-13 50.3 17.9 3.8e-13 49.6 17.9 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 RLN38373.1 - 2.6e-07 30.5 7.2 0.0015 18.4 1.2 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 RLN38373.1 - 0.00017 21.6 6.2 0.055 13.5 0.9 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 RLN38373.1 - 0.0052 16.8 10.0 0.0082 16.1 10.0 1.3 1 0 0 1 1 1 1 Double zinc ribbon DUF2318 PF10080.9 RLN38373.1 - 0.056 13.6 3.7 0.074 13.2 0.1 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) zinc_ribbon_15 PF17032.5 RLN38373.1 - 0.52 11.1 4.7 10 7.0 0.7 2.2 2 0 0 2 2 2 0 zinc-ribbon family Cytochrome_CBB3 PF13442.6 RLN38373.1 - 0.75 10.2 7.9 1.3 9.4 0.1 2.8 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 RLN38373.1 - 2.7 7.7 7.5 4.2 7.1 3.1 2.4 1 1 1 2 2 2 0 Cytochrome c-550 domain DUF1272 PF06906.11 RLN38373.1 - 4.4 7.5 6.9 6.7 6.9 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-TFIIB PF13453.6 RLN38373.1 - 5.3 6.5 14.5 12 5.3 0.1 4.1 3 1 2 5 5 5 0 Transcription factor zinc-finger A2L_zn_ribbon PF08792.10 RLN38373.1 - 7.6 6.4 16.6 0.15 11.8 2.5 3.0 2 1 1 3 3 3 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.10 RLN38373.1 - 9.9 6.4 14.2 59 3.9 0.2 4.1 1 1 2 3 3 3 0 Zinc ribbon domain PIP5K PF01504.18 RLN38386.1 - 5.8e-73 245.5 0.0 1e-71 241.4 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase COPIIcoated_ERV PF07970.12 RLN38386.1 - 1.3e-33 116.7 0.7 2.7e-33 115.7 0.1 1.9 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter Frizzled PF01534.17 RLN38386.1 - 0.0017 17.5 8.4 0.069 12.2 8.4 2.3 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region Glyco_transf_28 PF03033.20 RLN38387.1 - 2.3e-07 30.9 0.0 9.5e-07 28.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 RLN38387.1 - 1.5e-06 28.5 0.0 9.3e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 RLN38387.1 - 0.0074 16.1 0.3 0.015 15.0 0.3 1.5 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Cas_CXXC_CXXC PF09706.10 RLN38387.1 - 0.026 14.7 0.0 0.08 13.2 0.0 1.8 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) Glyco_transf_28 PF03033.20 RLN38388.1 - 2.5e-28 98.9 0.4 1e-20 74.2 0.1 4.0 2 2 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 RLN38388.1 - 0.00011 21.1 0.0 0.0002 20.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 RLN38388.1 - 0.0014 18.9 0.0 0.013 15.8 0.0 2.6 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 RLN38388.1 - 0.0014 18.4 0.3 0.0025 17.6 0.3 1.3 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal ERGIC_N PF13850.6 RLN38389.1 - 1.9e-15 57.0 0.0 2.8e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) COPIIcoated_ERV PF07970.12 RLN38389.1 - 0.00035 20.5 0.0 0.00046 20.1 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter GST_N_3 PF13417.6 RLN38390.1 - 3.7e-13 49.7 0.0 6.4e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN38390.1 - 1.8e-08 34.5 0.0 2.9e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RLN38390.1 - 0.00022 21.5 0.1 0.0012 19.2 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 RLN38390.1 - 0.0009 19.4 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_4 PF17172.4 RLN38390.1 - 0.014 16.2 0.0 0.024 15.4 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Glutaredoxin2_C PF04399.13 RLN38390.1 - 0.08 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Fic PF02661.18 RLN38391.1 - 4.8e-13 49.8 0.0 1.2e-12 48.6 0.0 1.7 1 0 0 1 1 1 1 Fic/DOC family Flg_hook PF02120.16 RLN38394.1 - 0.076 12.9 1.2 0.1 12.5 0.2 1.8 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK HAUS5 PF14817.6 RLN38394.1 - 0.12 11.1 0.6 0.14 10.9 0.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Ead_Ea22 PF13935.6 RLN38394.1 - 0.12 13.0 0.0 0.16 12.7 0.0 1.2 1 0 0 1 1 1 0 Ead/Ea22-like protein Ank_2 PF12796.7 RLN38395.1 - 1.1e-19 70.8 0.6 8.6e-11 42.3 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN38395.1 - 1.3e-15 57.6 0.0 0.0019 18.7 0.0 3.4 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN38395.1 - 3.9e-15 55.5 0.7 0.00021 21.6 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 RLN38395.1 - 2.6e-13 49.9 1.9 0.0014 18.8 0.0 5.1 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN38395.1 - 1.9e-12 46.2 0.6 0.1 13.2 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat DUF4988 PF16378.5 RLN38397.1 - 0.0021 17.8 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function Retrotran_gag_2 PF14223.6 RLN38398.1 - 7.2e-10 38.7 0.9 1.1e-09 38.1 0.9 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Piwi PF02171.17 RLN38399.1 - 9.4e-97 323.9 0.0 1.3e-96 323.4 0.0 1.1 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 RLN38399.1 - 5.4e-23 81.3 0.0 9.5e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 RLN38399.1 - 7e-19 68.8 0.0 1.5e-18 67.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoMid PF16487.5 RLN38399.1 - 3.9e-15 55.9 0.1 9.8e-15 54.6 0.1 1.7 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL1 PF08699.10 RLN38399.1 - 2.8e-13 49.3 0.1 6.6e-13 48.1 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 RLN38399.1 - 6.7e-13 48.8 0.0 1.8e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain Pkinase_Tyr PF07714.17 RLN38400.1 - 9.3e-118 392.2 0.0 1.4e-44 152.4 0.0 3.6 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 RLN38400.1 - 5.2e-108 360.4 0.0 1.8e-43 148.8 0.0 3.6 3 0 0 3 3 3 3 Protein kinase domain Kinase-like PF14531.6 RLN38400.1 - 4.2e-08 32.9 0.0 0.015 14.7 0.0 3.6 4 0 0 4 4 4 3 Kinase-like Kdo PF06293.14 RLN38400.1 - 7.4e-08 32.0 0.3 0.013 14.9 0.0 4.2 4 0 0 4 4 4 3 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RLN38400.1 - 3.7e-06 26.7 0.0 0.46 10.1 0.0 3.7 3 0 0 3 3 3 3 RIO1 family APH PF01636.23 RLN38400.1 - 1.8e-05 24.8 4.4 0.051 13.5 0.0 4.3 4 0 0 4 4 4 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 RLN38400.1 - 0.0029 17.2 0.7 11 5.4 0.0 4.3 5 0 0 5 5 5 1 PhoP regulatory network protein YrbL SesA PF17107.5 RLN38400.1 - 0.7 10.1 5.2 1.7 8.9 0.0 3.6 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Mito_carr PF00153.27 RLN38401.1 - 8.5e-15 54.4 2.1 9.1e-15 54.4 0.5 1.8 1 1 1 2 2 2 1 Mitochondrial carrier protein PepSY_2 PF13670.6 RLN38401.1 - 0.11 12.6 1.8 0.14 12.1 1.8 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain cNMP_binding PF00027.29 RLN38402.1 - 1.5e-18 66.6 0.0 7.9e-08 32.3 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN38402.1 - 1e-14 54.4 17.8 3.8e-07 29.6 1.1 3.2 2 1 0 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 RLN38402.1 - 3.2e-14 52.6 15.4 6.1e-09 35.7 3.9 4.0 3 0 0 3 3 3 3 Ion channel PX PF00787.24 RLN38405.1 - 1.7e-06 28.0 0.0 3.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 PX domain HECT PF00632.25 RLN38406.1 - 3.3e-52 177.9 0.0 4.1e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Adaptin_N PF01602.20 RLN38407.1 - 6.7e-53 180.0 0.0 9.4e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region AP4E_app_platf PF14807.6 RLN38407.1 - 6e-26 90.7 0.0 9.6e-26 90.1 0.0 1.3 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform Cnd1 PF12717.7 RLN38407.1 - 0.0014 18.7 0.0 0.0072 16.4 0.0 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 RLN38407.1 - 0.36 11.4 2.4 5 7.7 0.0 3.3 3 0 0 3 3 3 0 HEAT-like repeat Paf1 PF03985.13 RLN38408.1 - 4.4e-46 157.7 10.4 2.5e-45 155.2 0.9 3.7 2 1 2 4 4 4 3 Paf1 DUF4370 PF14290.6 RLN38408.1 - 0.021 14.7 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4370) Period_C PF12114.8 RLN38408.1 - 0.72 9.4 5.4 1.2 8.6 5.4 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region MRP-L28 PF09812.9 RLN38408.1 - 3.1 7.9 8.3 0.14 12.3 1.8 2.0 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L28 Ank_4 PF13637.6 RLN38409.1 - 3.5e-20 72.1 0.1 2.6e-05 24.7 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN38409.1 - 1.1e-13 51.5 0.1 9.2e-09 35.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RLN38409.1 - 1.3e-12 47.6 0.4 0.00034 20.9 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 RLN38409.1 - 4.6e-12 45.9 0.5 0.0041 17.4 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN38409.1 - 2.9e-07 30.3 0.5 0.61 10.8 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat ROK PF00480.20 RLN38410.1 - 5e-09 36.1 0.0 4e-06 26.5 0.0 2.0 1 1 1 2 2 2 2 ROK family BcrAD_BadFG PF01869.20 RLN38410.1 - 0.00097 18.7 0.0 0.00097 18.7 0.0 1.2 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 RLN38410.1 - 0.0029 17.2 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain SPRY PF00622.28 RLN38413.1 - 3e-24 85.4 0.0 5.1e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Sde2_N_Ubi PF13019.6 RLN38413.1 - 7.9e-17 61.6 1.0 7.9e-17 61.6 1.0 3.0 3 0 0 3 3 3 1 Silencing defective 2 N-terminal ubiquitin domain Telomere_Sde2_2 PF13297.6 RLN38413.1 - 3.1e-10 39.5 0.8 7.4e-10 38.3 0.3 1.9 2 0 0 2 2 2 1 Telomere stability C-terminal Ribosomal_60s PF00428.19 RLN38413.1 - 0.32 11.6 7.3 1.2 9.7 7.3 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein CPSF100_C PF13299.6 RLN38413.1 - 2 8.6 4.5 1.4 9.0 0.3 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Frigida PF07899.11 RLN38414.1 - 0.022 14.0 0.5 36 3.5 0.0 3.6 3 1 1 4 4 4 0 Frigida-like protein MA3 PF02847.17 RLN38414.1 - 0.043 13.8 0.1 4.5 7.3 0.0 3.2 2 1 0 3 3 3 0 MA3 domain PPR PF01535.20 RLN38414.1 - 0.18 12.1 0.0 19 5.8 0.0 3.0 3 0 0 3 3 3 0 PPR repeat zf-RING_2 PF13639.6 RLN38415.1 - 2.6e-12 46.9 5.4 3.4e-12 46.5 5.4 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN38415.1 - 4.2e-10 39.3 5.5 5.9e-10 38.8 5.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN38415.1 - 1.9e-09 37.1 2.1 1.9e-09 37.1 2.1 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 RLN38415.1 - 3.9e-08 33.4 7.7 1.2e-07 31.9 7.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RLN38415.1 - 1e-07 31.7 3.4 1.4e-07 31.2 3.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN38415.1 - 3.4e-06 26.9 3.5 4.6e-06 26.5 3.5 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RLN38415.1 - 2.4e-05 24.3 0.6 2.4e-05 24.3 0.6 1.5 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RLN38415.1 - 0.00015 21.6 2.6 0.00021 21.1 2.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN38415.1 - 0.0026 17.6 3.4 0.0052 16.6 3.4 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 RLN38415.1 - 0.004 17.4 2.8 0.0054 17.0 2.8 1.2 1 0 0 1 1 1 1 RING-like domain ZZ PF00569.17 RLN38415.1 - 0.0046 16.7 1.2 0.32 10.8 0.2 2.2 2 0 0 2 2 2 1 Zinc finger, ZZ type zf-ANAPC11 PF12861.7 RLN38415.1 - 0.0047 16.9 5.8 0.042 13.9 5.8 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 RLN38415.1 - 0.0084 15.7 3.1 0.013 15.1 3.1 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-HC5HC2H_2 PF13832.6 RLN38415.1 - 0.039 14.1 2.3 0.088 13.0 2.5 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain RINGv PF12906.7 RLN38415.1 - 0.048 13.8 4.0 0.16 12.1 1.0 2.2 2 0 0 2 2 2 0 RING-variant domain PHD PF00628.29 RLN38415.1 - 0.061 13.2 2.6 0.11 12.4 2.6 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 RLN38415.1 - 0.43 10.8 6.6 2.8 8.2 6.6 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 RLN38415.1 - 0.48 10.7 3.5 0.52 10.6 1.9 1.8 1 1 1 2 2 2 0 PHD-like zinc-binding domain DHC_N1 PF08385.12 RLN38417.1 - 8.2e-187 622.3 0.4 8.2e-187 622.3 0.4 3.4 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 RLN38417.1 - 1.5e-115 386.5 14.5 1.5e-115 386.5 14.5 3.8 3 1 1 4 4 4 2 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 RLN38417.1 - 6.3e-12 45.1 1.0 1.5e-11 43.9 0.1 2.1 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region BCDHK_Adom3 PF10436.9 RLN38417.1 - 0.0038 17.1 0.3 0.029 14.2 0.1 2.6 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Uteroglobin PF01099.17 RLN38417.1 - 0.47 10.8 3.5 0.9 9.9 0.4 3.1 3 0 0 3 3 3 0 Uteroglobin family DivIVA PF05103.13 RLN38417.1 - 6.3 6.9 7.2 10 6.2 0.4 3.7 3 0 0 3 3 3 0 DivIVA protein OTCace_N PF02729.21 RLN38418.1 - 2.7e-26 92.3 0.0 5.3e-26 91.4 0.0 1.5 1 1 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 RLN38418.1 - 1.1e-20 74.3 0.1 1.1e-13 51.5 0.1 2.3 2 0 0 2 2 2 2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain NAD_binding_1 PF00175.21 RLN38419.1 - 2.6e-11 44.1 0.0 3.2e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Tup_N PF08581.10 RLN38420.1 - 0.012 15.9 1.3 0.012 15.9 1.3 5.9 3 2 1 5 5 5 0 Tup N-terminal SlyX PF04102.12 RLN38420.1 - 0.017 15.7 0.5 0.017 15.7 0.5 6.8 5 2 1 7 7 7 0 SlyX EF-hand_6 PF13405.6 RLN38431.1 - 4.3e-07 29.3 1.9 0.8 9.8 0.0 6.2 8 0 0 8 8 8 3 EF-hand domain EF-hand_7 PF13499.6 RLN38431.1 - 1.7e-06 28.3 1.5 0.71 10.4 0.0 5.6 6 0 0 6 6 6 3 EF-hand domain pair EF-hand_1 PF00036.32 RLN38431.1 - 8.4e-05 21.9 0.3 0.17 11.5 0.0 4.3 4 0 0 4 4 4 2 EF hand E1-E2_ATPase PF00122.20 RLN38432.1 - 1.1e-31 109.8 0.0 6.9e-31 107.2 0.0 2.5 1 1 1 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 RLN38432.1 - 9.5e-09 35.8 0.0 5.2e-07 30.2 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RLN38432.1 - 7.6e-07 28.7 0.0 3.8e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 RLN38432.1 - 0.0057 16.7 0.0 0.028 14.5 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Fe_bilin_red PF05996.12 RLN38433.1 - 0.12 12.1 1.9 0.98 9.1 0.1 2.6 3 0 0 3 3 3 0 Ferredoxin-dependent bilin reductase DUF4269 PF14091.6 RLN38433.1 - 0.3 11.3 3.2 0.19 12.0 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4269) MRP-L28 PF09812.9 RLN38433.1 - 1.3 9.1 15.7 1.6 8.9 6.9 2.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 MFS_1 PF07690.16 RLN38434.1 - 3.4e-19 69.0 26.3 3.4e-19 69.0 26.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN38434.1 - 4.7e-06 25.7 7.8 4.7e-06 25.7 7.8 2.4 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 RLN38434.1 - 4.7e-05 22.4 9.4 0.0063 15.4 0.2 3.1 1 1 2 3 3 3 3 MFS_1 like family DUF3792 PF12670.7 RLN38434.1 - 0.031 14.4 0.8 0.031 14.4 0.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) MFS_5 PF05631.14 RLN38434.1 - 0.052 12.5 6.9 0.11 11.5 6.9 1.7 1 1 0 1 1 1 0 Sugar-tranasporters, 12 TM SLATT_3 PF18184.1 RLN38434.1 - 0.13 12.4 0.5 0.37 10.9 0.5 1.8 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 PLAC8 PF04749.17 RLN38436.1 - 1.1e-13 52.0 12.8 1.1e-13 52.0 12.8 2.9 2 1 0 2 2 2 1 PLAC8 family PrsW-protease PF13367.6 RLN38436.1 - 5e-07 29.4 11.9 5e-07 29.4 11.9 3.4 3 1 0 3 3 3 1 PrsW family intramembrane metalloprotease TauD PF02668.16 RLN38437.1 - 4.1e-38 131.7 0.0 5.9e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 RLN38437.1 - 0.005 17.5 0.0 0.016 15.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 RLN38437.1 - 0.012 14.7 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 CsiD MFS_1 PF07690.16 RLN38438.1 - 1.8e-21 76.5 20.3 2.9e-21 75.8 20.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN38438.1 - 1.3e-05 24.2 5.8 1.3e-05 24.2 5.8 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Nuc_H_symport PF03825.16 RLN38438.1 - 0.00092 18.3 9.2 0.0029 16.6 1.4 2.2 2 0 0 2 2 2 2 Nucleoside H+ symporter MFS_1_like PF12832.7 RLN38438.1 - 0.0024 16.8 8.3 0.036 12.9 0.4 2.7 1 1 2 3 3 3 2 MFS_1 like family MFS_5 PF05631.14 RLN38438.1 - 0.0034 16.4 2.9 0.0044 16.0 2.5 1.7 1 1 0 1 1 1 1 Sugar-tranasporters, 12 TM DUF3792 PF12670.7 RLN38438.1 - 0.22 11.7 19.8 0.038 14.1 2.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) bZIP_1 PF00170.21 RLN38439.1 - 0.013 15.6 0.4 0.013 15.6 0.4 2.8 2 1 1 3 3 3 0 bZIP transcription factor DUF1858 PF08984.11 RLN38439.1 - 0.18 12.0 0.0 0.74 10.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1858) DUF4407 PF14362.6 RLN38439.1 - 5.4 6.3 9.1 7.3 5.8 9.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RNA12 PF10443.9 RLN38440.1 - 0.057 12.1 0.3 0.086 11.6 0.3 1.2 1 0 0 1 1 1 0 RNA12 protein LRR_4 PF12799.7 RLN38443.1 - 0.14 12.6 7.5 0.7 10.4 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) ABC_membrane PF00664.23 RLN38445.1 - 4e-86 289.1 25.8 7.4e-42 143.9 15.7 3.2 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 RLN38445.1 - 5.1e-71 237.6 0.0 1.7e-34 119.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN38445.1 - 1.8e-11 43.9 1.4 0.00013 21.5 0.0 4.0 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 RLN38445.1 - 2.5e-08 33.5 0.0 0.0022 17.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin ABC_ATPase PF09818.9 RLN38445.1 - 1.6e-07 30.6 0.9 0.0092 14.8 0.1 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 RLN38445.1 - 1.7e-07 31.8 2.1 0.0044 17.4 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 RLN38445.1 - 2.7e-07 30.2 0.9 0.024 14.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN38445.1 - 4.9e-07 30.1 1.2 0.068 13.4 0.1 3.7 2 2 0 2 2 2 2 AAA domain AAA PF00004.29 RLN38445.1 - 5.2e-06 26.9 2.1 0.012 16.1 0.1 4.0 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 RLN38445.1 - 1.6e-05 24.9 0.5 0.21 11.5 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_15 PF13175.6 RLN38445.1 - 1.7e-05 24.7 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 RLN38445.1 - 4.9e-05 23.1 1.4 0.47 10.1 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.6 RLN38445.1 - 0.0001 22.2 0.0 0.91 9.3 0.0 3.6 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system APS_kinase PF01583.20 RLN38445.1 - 0.00012 22.1 0.0 0.75 9.7 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_25 PF13481.6 RLN38445.1 - 0.00017 21.2 1.1 0.54 9.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain SRP54 PF00448.22 RLN38445.1 - 0.00018 21.2 0.0 4.2 6.9 0.0 3.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_28 PF13521.6 RLN38445.1 - 0.00039 20.7 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 RLN38445.1 - 0.00042 20.9 0.0 1.4 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 RLN38445.1 - 0.00065 19.7 0.1 0.81 9.7 0.0 3.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) DUF87 PF01935.17 RLN38445.1 - 0.00074 19.7 1.3 0.45 10.6 0.1 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain G-alpha PF00503.20 RLN38445.1 - 0.00083 18.6 0.0 0.82 8.8 0.0 2.5 2 0 0 2 2 2 2 G-protein alpha subunit AAA_33 PF13671.6 RLN38445.1 - 0.00085 19.5 0.0 1.8 8.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain MgtE PF01769.16 RLN38445.1 - 0.0009 19.6 5.6 0.0009 19.6 5.6 4.1 5 1 0 5 5 2 1 Divalent cation transporter AAA_7 PF12775.7 RLN38445.1 - 0.0014 18.2 0.0 0.81 9.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 RLN38445.1 - 0.0023 17.7 0.0 0.91 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 RLN38445.1 - 0.0098 16.1 3.0 6.5 7.1 0.2 3.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 RLN38445.1 - 0.011 15.7 1.3 27 4.6 0.0 4.0 4 0 0 4 4 4 0 NACHT domain MMR_HSR1 PF01926.23 RLN38445.1 - 0.027 14.6 0.2 9.3 6.4 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 RLN38445.1 - 0.031 13.6 0.0 3.6 6.9 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.17 RLN38445.1 - 0.05 13.3 0.1 14 5.4 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 RLN38445.1 - 0.066 12.6 0.0 4.1 6.7 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 RLN38445.1 - 0.072 13.0 0.0 5.1 7.0 0.0 2.7 3 0 0 3 3 2 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 RLN38445.1 - 0.092 12.5 0.2 6.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF3148 PF11347.8 RLN38445.1 - 0.13 12.0 0.0 4.3 7.2 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3148) AAA_23 PF13476.6 RLN38445.1 - 0.14 12.6 0.2 26 5.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 RLN38445.1 - 1.4 8.7 4.4 34 4.1 0.5 3.5 2 2 0 2 2 2 0 DEAD/DEAH box helicase SET PF00856.28 RLN38446.1 - 2.4e-17 63.8 0.1 2.1e-15 57.5 0.0 2.7 3 1 0 3 3 3 1 SET domain R3H-assoc PF13902.6 RLN38446.1 - 1.4 9.3 8.1 0.18 12.2 0.9 2.7 2 0 0 2 2 2 0 R3H-associated N-terminal domain zf-MYND PF01753.18 RLN38446.1 - 2.9 8.1 11.6 0.049 13.7 3.5 2.3 2 0 0 2 2 2 0 MYND finger ThiF PF00899.21 RLN38447.1 - 4.3e-25 88.5 0.0 1.5e-24 86.7 0.0 1.8 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 RLN38447.1 - 0.0019 18.4 0.3 11 6.2 0.0 3.5 3 0 0 3 3 3 2 Ubiquitin-activating enzyme E1 four-helix bundle NAD_binding_7 PF13241.6 RLN38447.1 - 0.017 15.6 0.0 0.052 14.0 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 RLN38447.1 - 0.036 14.1 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase BacteriocIIc_cy PF12173.8 RLN38447.1 - 0.065 13.5 0.0 0.24 11.7 0.0 2.0 1 0 0 1 1 1 0 Bacteriocin class IIc cyclic gassericin A-like DUF1972 PF09314.11 RLN38447.1 - 0.21 11.1 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1972) NOG1 PF06858.14 RLN38459.1 - 4.6e-12 45.5 0.0 9.6e-12 44.5 0.0 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOG1_N PF17835.1 RLN38459.1 - 6.6e-08 32.7 0.7 1.5e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 NOG1 N-terminal helical domain CDP-OH_P_transf PF01066.21 RLN38460.1 - 2.1e-15 57.2 0.1 2.1e-15 57.2 0.1 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Pkinase_Tyr PF07714.17 RLN38462.1 - 4.4e-09 36.0 0.0 7.3e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN38462.1 - 1e-08 34.9 0.0 1.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain BDV_G PF06208.11 RLN38464.1 - 0.081 12.1 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Borna disease virus G protein CDPS PF16715.5 RLN38464.1 - 0.13 11.9 0.2 0.32 10.6 0.0 1.7 2 0 0 2 2 2 0 Cyclodipeptide synthase Ku PF02735.16 RLN38465.1 - 1.5e-47 162.0 0.0 2.3e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 RLN38465.1 - 9.8e-15 54.9 0.0 2.2e-14 53.8 0.0 1.6 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SHR3_chaperone PF08229.11 RLN38465.1 - 0.02 13.9 0.1 0.036 13.1 0.1 1.4 1 0 0 1 1 1 0 ER membrane protein SH3 FANCL_C PF11793.8 RLN38466.1 - 0.22 11.7 5.3 0.49 10.6 3.6 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain p450 PF00067.22 RLN38488.1 - 1.2e-66 225.4 1.2 1.5e-66 225.1 1.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 SSF PF00474.17 RLN38501.1 - 5.9e-08 32.0 14.7 5.9e-08 32.0 14.7 1.7 1 1 0 1 1 1 1 Sodium:solute symporter family Tub PF01167.18 RLN38502.1 - 4.6e-50 170.6 0.0 1.1e-49 169.3 0.0 1.6 1 1 0 1 1 1 1 Tub family zf-RING_2 PF13639.6 RLN38502.1 - 2.8e-09 37.1 11.5 2.8e-09 37.1 11.5 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN38502.1 - 3.6e-08 33.1 10.1 3.6e-08 33.1 10.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN38502.1 - 5.2e-07 29.4 14.4 6.2e-07 29.2 9.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN38502.1 - 1.5e-05 24.7 11.6 1.5e-05 24.7 11.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN38502.1 - 0.00011 22.1 8.7 0.00038 20.4 6.4 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 RLN38502.1 - 0.00048 20.3 9.2 0.00048 20.3 9.2 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 RLN38502.1 - 0.00053 19.8 11.5 0.0013 18.6 8.5 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 RLN38502.1 - 0.059 13.3 5.5 0.16 11.9 5.5 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 RLN38502.1 - 0.084 12.9 16.0 0.022 14.7 11.4 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-Di19 PF05605.12 RLN38502.1 - 0.096 13.0 8.0 0.098 13.0 0.1 3.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-ANAPC11 PF12861.7 RLN38502.1 - 0.19 11.8 5.5 0.051 13.6 2.1 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF935 PF06074.12 RLN38502.1 - 0.41 9.3 5.6 0.62 8.7 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) zf-C3HC4_4 PF15227.6 RLN38502.1 - 0.5 10.6 14.5 0.45 10.7 11.1 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FYVE PF01363.21 RLN38502.1 - 0.75 10.0 14.9 4.2 7.6 14.9 2.1 1 1 0 1 1 1 0 FYVE zinc finger Baculo_IE-1 PF05290.11 RLN38502.1 - 0.81 9.6 6.9 1.1 9.2 6.3 1.5 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zinc-ribbons_6 PF07191.12 RLN38502.1 - 4.7 7.3 12.6 5.4 7.1 7.0 2.4 2 0 0 2 2 2 0 zinc-ribbons F420_oxidored PF03807.17 RLN38503.1 - 0.00046 20.7 0.2 0.004 17.7 0.0 2.3 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_1 PF00175.21 RLN38503.1 - 0.14 12.8 0.1 0.31 11.7 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Suc_Fer-like PF06999.12 RLN38504.1 - 2.7e-13 50.2 0.0 4.7e-09 36.4 0.0 2.1 1 1 1 2 2 2 2 Sucrase/ferredoxin-like Claudin_3 PF06653.11 RLN38512.1 - 0.00016 21.6 7.5 0.0096 15.9 1.4 2.5 2 1 1 3 3 3 2 Tight junction protein, Claudin-like Claudin_2 PF13903.6 RLN38512.1 - 0.95 9.2 13.6 43 3.8 13.6 2.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Galactosyl_T PF01762.21 RLN38513.1 - 1.6e-22 80.3 0.5 1.1e-21 77.5 0.5 2.1 1 1 0 1 1 1 1 Galactosyltransferase Glyco_transf_10 PF00852.19 RLN38513.1 - 3.6e-20 72.4 0.0 7.9e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Fringe PF02434.16 RLN38513.1 - 0.074 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Fringe-like Flp_C PF05202.12 RLN38513.1 - 0.21 11.1 0.1 0.34 10.4 0.1 1.2 1 0 0 1 1 1 0 Recombinase Flp protein Galactosyl_T PF01762.21 RLN38514.1 - 3.3e-23 82.5 0.0 4.7e-21 75.5 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase Galactosyl_T PF01762.21 RLN38515.1 - 2.8e-25 89.3 0.0 3.9e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Galactosyl_T PF01762.21 RLN38516.1 - 1.5e-27 96.7 0.0 2.6e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 RLN38516.1 - 0.0063 16.0 0.2 0.11 11.9 0.0 2.3 2 0 0 2 2 2 1 Fringe-like baeRF_family6 PF18848.1 RLN38517.1 - 0.068 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 6 PH PF00169.29 RLN38518.1 - 1.3e-08 35.3 0.0 2.7e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN38518.1 - 0.00017 21.8 0.0 0.00045 20.5 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Chalcone_2 PF16035.5 RLN38519.1 - 0.048 13.4 0.3 4.2 7.1 0.1 2.4 2 0 0 2 2 2 0 Chalcone isomerase like SAP PF02037.27 RLN38519.1 - 0.21 11.4 1.8 15 5.5 0.0 3.3 3 0 0 3 3 3 0 SAP domain Ras PF00071.22 RLN38520.1 - 5.8e-42 143.0 0.0 8.5e-42 142.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN38520.1 - 1.4e-18 67.2 0.0 2.4e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase BLOC1_2 PF10046.9 RLN38520.1 - 7e-06 26.3 0.6 1.4e-05 25.3 0.6 1.4 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Arf PF00025.21 RLN38520.1 - 1.2e-05 24.8 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family V-SNARE PF05008.15 RLN38520.1 - 0.0038 17.6 0.4 0.0074 16.6 0.4 1.4 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus PX PF00787.24 RLN38521.1 - 6.9e-10 38.9 0.2 3.3e-09 36.7 0.0 2.1 2 0 0 2 2 2 1 PX domain Abhydrolase_1 PF00561.20 RLN38522.1 - 1.1e-07 31.8 0.1 0.001 18.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN38522.1 - 0.00014 21.3 0.0 0.018 14.3 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN38522.1 - 0.0046 17.6 0.8 1.3 9.6 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 RLN38522.1 - 0.2 11.2 0.1 11 5.5 0.0 2.4 2 1 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) WW PF00397.26 RLN38524.1 - 2.2e-08 34.0 1.6 4.7e-08 33.0 1.6 1.6 1 0 0 1 1 1 1 WW domain Ank_2 PF12796.7 RLN38526.1 - 6.1e-17 62.0 0.5 2.2e-07 31.4 0.0 3.1 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN38526.1 - 2e-15 57.0 3.5 2e-07 31.4 0.1 4.5 2 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN38526.1 - 1.2e-11 44.6 1.6 0.0071 16.6 0.1 5.0 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN38526.1 - 1.9e-07 30.8 0.2 4.8 8.1 0.0 6.3 6 0 0 6 6 6 2 Ankyrin repeat Mannosyl_trans3 PF11051.8 RLN38529.1 - 1.9e-14 53.7 0.0 2.9e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Pkinase_Tyr PF07714.17 RLN38529.1 - 2.5e-06 27.0 0.1 6.2e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RLN38529.1 - 0.0027 17.1 0.0 0.0087 15.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain zf-C3HC4_3 PF13920.6 RLN38530.1 - 0.00015 21.6 11.0 0.00015 21.6 11.0 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.6 RLN38530.1 - 0.024 15.4 0.2 0.024 15.4 0.2 6.4 6 1 0 6 6 6 0 C2H2-type zinc finger zf-C2H2 PF00096.26 RLN38530.1 - 0.12 12.9 0.2 0.12 12.9 0.2 5.5 5 0 0 5 5 5 0 Zinc finger, C2H2 type WH2 PF02205.20 RLN38531.1 - 7.6e-11 41.5 12.0 4.3e-08 32.7 0.8 3.1 3 0 0 3 3 3 2 WH2 motif WW PF00397.26 RLN38531.1 - 5e-06 26.5 6.4 8.4e-06 25.8 6.4 1.4 1 0 0 1 1 1 1 WW domain stn_TNFRSF12A PF12191.8 RLN38535.1 - 0.18 12.0 1.7 0.88 9.8 0.2 2.2 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Asp_Glu_race PF01177.22 RLN38536.1 - 2.5e-24 86.4 0.0 7.3e-24 84.9 0.0 1.7 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase DUF4407 PF14362.6 RLN38537.1 - 0.13 11.6 8.6 0.2 11.0 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 RLN38537.1 - 0.68 10.6 3.0 3.3 8.4 0.1 2.4 2 0 0 2 2 2 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 RLN38537.1 - 1.4 8.9 11.9 33 4.5 11.9 2.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Com_YlbF PF06133.11 RLN38537.1 - 1.8 9.2 8.0 8 7.1 0.6 2.5 3 0 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA THOC7 PF05615.13 RLN38537.1 - 2.3 8.5 13.6 7.1 6.9 0.5 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 AAA_13 PF13166.6 RLN38537.1 - 3.8 6.0 6.6 7.1 5.1 6.6 1.3 1 1 0 1 1 1 0 AAA domain DUF3450 PF11932.8 RLN38537.1 - 4.1 6.6 15.5 0.16 11.3 6.9 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) GAS PF13851.6 RLN38537.1 - 6.1 6.1 12.1 2.3 7.5 4.3 2.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Aldedh PF00171.22 RLN38549.1 - 1.2e-76 258.1 0.1 1.3e-76 258.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 RLN38549.1 - 0.019 14.4 0.0 0.45 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Pyr_redox_2 PF07992.14 RLN38550.1 - 2.7e-13 49.8 0.1 7e-12 45.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RLN38550.1 - 0.00015 22.0 0.0 0.00035 20.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 RLN38550.1 - 0.0006 19.2 0.1 0.0033 16.7 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 RLN38550.1 - 0.0041 16.4 0.0 0.26 10.5 0.0 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 RLN38550.1 - 0.0045 17.4 0.1 2.7 8.5 0.0 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding Pyr_redox PF00070.27 RLN38550.1 - 0.11 13.0 1.3 1.8 9.2 0.1 2.8 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Myosin_head PF00063.21 RLN38551.1 - 2.2e-226 753.2 0.3 6.8e-226 751.6 0.3 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_N PF02736.19 RLN38551.1 - 0.0011 18.8 0.1 0.0024 17.7 0.1 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.27 RLN38551.1 - 0.0035 17.0 24.5 0.025 14.3 0.3 5.2 5 0 0 5 5 5 2 IQ calmodulin-binding motif AAA_22 PF13401.6 RLN38551.1 - 0.021 15.1 0.0 0.093 13.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RLN38551.1 - 0.035 14.5 0.0 0.14 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 RLN38551.1 - 0.037 13.3 0.0 0.077 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 RLN38551.1 - 0.055 14.0 0.0 0.16 12.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 RLN38551.1 - 0.072 13.6 0.2 0.31 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain RAP PF08373.10 RLN38551.1 - 0.2 11.8 3.1 2.6 8.2 0.3 2.9 2 0 0 2 2 2 0 RAP domain WW PF00397.26 RLN38552.1 - 1.1e-41 140.5 42.0 1.5e-07 31.3 0.9 7.3 7 0 0 7 7 7 6 WW domain IQ PF00612.27 RLN38552.1 - 5e-23 78.7 51.4 0.0041 16.8 0.1 10.8 11 0 0 11 11 11 8 IQ calmodulin-binding motif LRR_4 PF12799.7 RLN38552.1 - 2.8e-13 49.8 2.5 2.1 8.9 0.0 7.5 4 1 3 8 8 8 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RLN38552.1 - 2.3e-11 42.8 13.6 0.19 11.9 0.0 10.3 11 0 0 11 11 11 3 Leucine Rich repeat LRR_1 PF00560.33 RLN38552.1 - 0.00057 20.1 12.0 67 4.6 0.2 8.6 8 2 1 9 9 9 0 Leucine Rich Repeat PQQ PF01011.21 RLN38552.1 - 0.0083 16.0 3.1 11 6.2 0.1 4.6 5 0 0 5 5 5 1 PQQ enzyme repeat Glyco_hyd_101C PF17451.2 RLN38552.1 - 0.078 13.3 16.1 0.64 10.3 0.4 5.2 5 1 0 6 6 6 0 Glycosyl hydrolase 101 beta sandwich domain Spc24 PF08286.11 RLN38552.1 - 0.16 12.2 6.6 2.8 8.2 3.1 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 WW_1 PF18507.1 RLN38552.1 - 2.6 7.8 3.9 14 5.5 0.4 2.8 2 0 0 2 2 2 0 WW domain UPF0139 PF03669.13 RLN38553.1 - 7.4e-25 86.7 0.0 8.7e-25 86.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) OrfB_Zn_ribbon PF07282.11 RLN43528.1 - 5.3e-07 29.5 5.2 5.2e-06 26.3 5.2 2.4 1 1 0 1 1 1 1 Putative transposase DNA-binding domain PH PF00169.29 RLN43529.1 - 4e-09 36.9 0.1 1.6e-08 35.0 0.1 1.9 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 RLN43529.1 - 2.2e-05 24.6 0.4 0.00021 21.5 0.4 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain Cwf_Cwc_15 PF04889.12 RLN43529.1 - 0.016 15.0 9.9 0.025 14.3 9.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 RLN43529.1 - 0.016 15.3 14.5 0.016 15.3 14.5 1.8 2 0 0 2 2 2 0 YL1 nuclear protein HemY_N PF07219.13 RLN43529.1 - 0.12 12.6 2.6 0.7 10.1 0.1 2.5 2 0 0 2 2 2 0 HemY protein N-terminus RPN2_C PF18004.1 RLN43529.1 - 0.22 11.4 2.3 0.6 10.0 2.3 1.6 1 1 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DNA_pol_phi PF04931.13 RLN43529.1 - 0.24 9.4 12.5 0.34 9.0 12.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 RLN43529.1 - 0.31 11.1 1.9 0.5 10.4 1.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal SDA1 PF05285.12 RLN43529.1 - 0.39 10.1 6.7 0.57 9.6 6.7 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 RLN43529.1 - 0.62 9.4 11.9 0.99 8.7 11.9 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 RLN43529.1 - 0.9 7.7 8.5 1.2 7.2 8.5 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 RLN43529.1 - 1 8.6 10.4 1.6 8.0 10.4 1.2 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.13 RLN43529.1 - 1.7 8.6 8.4 0.42 10.6 5.6 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Sigma70_ner PF04546.13 RLN43529.1 - 4.2 7.2 6.3 7.5 6.4 6.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region zf-C2H2 PF00096.26 RLN43530.1 - 4.9e-16 58.2 23.3 0.00015 22.0 0.2 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN43530.1 - 4.2e-12 45.8 20.4 0.0026 18.4 0.1 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RLN43530.1 - 1.7e-08 34.5 24.7 6e-06 26.5 0.7 5.0 5 1 0 5 5 5 4 Zinc-finger double domain zf-C2H2_8 PF15909.5 RLN43530.1 - 6.7e-05 23.1 9.4 0.018 15.4 0.7 3.1 1 1 2 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 RLN43530.1 - 0.00031 21.0 8.7 0.037 14.2 1.7 3.5 1 1 2 3 3 3 2 Aberrant zinc-finger zf-H2C2_5 PF13909.6 RLN43530.1 - 0.00055 19.6 10.1 0.12 12.2 0.3 4.4 4 0 0 4 4 4 1 C2H2-type zinc-finger domain zf_ZIC PF18366.1 RLN43530.1 - 0.00076 19.5 1.5 2.2 8.5 0.1 3.7 2 1 1 3 3 3 1 Zic proteins zinc finger domain FOXP-CC PF16159.5 RLN43530.1 - 0.00097 19.7 7.3 0.016 15.8 0.1 2.9 3 1 0 3 3 3 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 RLN43530.1 - 0.0014 18.9 6.8 18 5.8 0.0 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 RLN43530.1 - 0.069 12.9 12.8 0.29 10.9 0.1 4.1 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-met PF12874.7 RLN43530.1 - 0.15 12.5 2.5 56 4.3 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RLN43530.1 - 0.41 10.7 16.5 0.48 10.5 0.6 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 RLN43530.1 - 4.3 7.9 9.0 77 3.9 0.0 4.1 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2 PF00096.26 RLN43531.1 - 4.3e-18 64.7 25.2 4.7e-05 23.6 0.5 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN43531.1 - 2.7e-15 55.7 22.1 0.00011 22.7 0.8 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RLN43531.1 - 1e-12 47.8 21.9 3.2e-06 27.3 1.3 5.5 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 RLN43531.1 - 2.4e-06 27.4 16.6 0.0031 17.5 0.5 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 RLN43531.1 - 1.3e-05 25.4 9.9 0.092 13.1 0.5 3.3 1 1 2 3 3 3 3 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 RLN43531.1 - 4e-05 23.8 5.7 0.49 10.7 0.0 4.4 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 RLN43531.1 - 0.00012 22.3 6.5 0.086 13.0 0.8 3.3 1 1 2 3 3 3 2 Aberrant zinc-finger zf-H2C2_5 PF13909.6 RLN43531.1 - 0.0013 18.4 13.7 1 9.2 1.8 4.5 4 0 0 4 4 4 2 C2H2-type zinc-finger domain FOXP-CC PF16159.5 RLN43531.1 - 0.0024 18.5 7.4 0.0058 17.2 0.1 3.1 3 1 0 3 3 3 1 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 RLN43531.1 - 0.0031 17.3 12.3 0.33 10.8 1.3 4.1 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-met PF12874.7 RLN43531.1 - 0.013 15.8 1.6 60 4.2 0.0 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf_ZIC PF18366.1 RLN43531.1 - 0.016 15.3 5.2 3.2 7.9 0.1 3.8 3 0 0 3 3 3 0 Zic proteins zinc finger domain HEPN_SAV_6107 PF18726.1 RLN43531.1 - 0.19 12.2 0.0 0.34 11.4 0.0 1.4 1 0 0 1 1 1 0 SAV_6107-like HEPN CHORD PF04968.12 RLN43531.1 - 0.64 10.8 14.5 15 6.4 0.2 4.2 2 2 2 4 4 4 0 CHORD Zn-C2H2_12 PF18112.1 RLN43531.1 - 2.5 8.6 9.0 76 3.9 1.8 4.6 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain Uso1_p115_head PF04869.14 RLN43548.1 - 1.6e-22 80.0 0.1 7.7e-16 58.1 0.0 2.7 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, head region HEAT PF02985.22 RLN43548.1 - 0.022 15.0 1.2 3.3 8.2 0.0 4.3 3 0 0 3 3 3 0 HEAT repeat Cnd1 PF12717.7 RLN43548.1 - 0.063 13.3 0.0 0.2 11.7 0.0 1.9 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 EF-hand_1 PF00036.32 RLN43550.1 - 0.0028 17.1 0.2 0.0047 16.4 0.2 1.4 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 RLN43550.1 - 0.0031 17.9 0.1 0.0053 17.2 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair Peptidase_M61 PF05299.12 RLN43550.1 - 0.11 13.0 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 M61 glycyl aminopeptidase Pkinase PF00069.25 RLN43558.1 - 1.4e-50 172.2 0.0 2.7e-49 167.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN43558.1 - 4.4e-25 88.4 0.0 4.5e-16 58.9 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RLN43558.1 - 1.2e-05 24.8 0.0 0.0023 17.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.11 RLN43558.1 - 0.00055 19.1 0.0 0.00079 18.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 RLN43558.1 - 0.001 18.1 0.0 0.013 14.4 0.1 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 RLN43558.1 - 0.0013 17.6 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Acyltransferase PF01553.21 RLN43562.1 - 1.7e-14 53.6 0.0 2.5e-13 49.8 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase RCDG1 PF15725.5 RLN43562.1 - 0.079 13.4 3.8 0.13 12.7 0.6 2.6 3 0 0 3 3 3 0 Renal cancer differentiation gene 1 protein CAP_N PF01213.19 RLN43562.1 - 0.1 12.1 0.5 0.15 11.5 0.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TPR_12 PF13424.6 RLN43563.1 - 8.3e-13 48.4 34.4 1.7e-07 31.4 4.0 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 RLN43563.1 - 5.1e-10 38.9 29.0 0.0012 18.6 0.1 7.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_4 PF07721.14 RLN43563.1 - 3.4e-08 33.4 17.0 0.31 11.8 0.1 8.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN43563.1 - 9.5e-08 31.6 16.2 0.019 14.8 0.0 7.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN43563.1 - 1e-07 31.5 25.7 0.2 11.9 0.1 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_MalT PF17874.1 RLN43563.1 - 0.0014 18.1 12.4 0.0014 18.1 12.4 3.9 5 0 0 5 5 5 2 MalT-like TPR region TPR_8 PF13181.6 RLN43563.1 - 0.0018 18.4 6.7 7.5 7.1 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN43563.1 - 0.0021 18.7 7.2 0.0021 18.7 7.2 7.4 6 1 1 7 7 7 1 Tetratricopeptide repeat RPN7 PF10602.9 RLN43563.1 - 0.013 15.2 0.4 0.049 13.3 0.4 2.0 1 0 0 1 1 1 0 26S proteasome subunit RPN7 DUF4611 PF15387.6 RLN43563.1 - 0.024 14.8 3.5 6.2 7.1 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) TPR_7 PF13176.6 RLN43563.1 - 0.058 13.4 28.1 1.4 9.1 0.1 8.2 9 1 0 9 9 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN43563.1 - 0.071 13.4 2.9 2.4 8.5 0.0 3.7 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 RLN43563.1 - 0.86 10.1 9.3 30 5.3 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN43563.1 - 0.92 10.5 38.5 3.1 8.8 2.8 8.9 8 2 1 9 9 7 0 Tetratricopeptide repeat Seryl_tRNA_N PF02403.22 RLN43563.1 - 1 9.7 0.0 1 9.7 0.0 3.1 4 0 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain TPR_6 PF13174.6 RLN43563.1 - 7 7.5 14.7 40 5.2 0.1 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Metallophos PF00149.28 RLN43564.1 - 6.9e-23 82.2 0.0 8.8e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RLN43564.1 - 7.4e-14 51.9 0.3 1.5e-13 50.9 0.3 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain SLM4 PF16818.5 RLN43564.1 - 0.14 12.1 0.2 0.31 11.0 0.2 1.6 1 1 1 2 2 2 0 Protein SLM4 NUDIX PF00293.28 RLN43565.1 - 6e-14 52.2 0.0 9.4e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain zf-Di19 PF05605.12 RLN43565.1 - 1.4e-08 34.8 0.1 3e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding NUDIX_2 PF13869.6 RLN43565.1 - 0.0087 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotide hydrolase zf-H2C2_2 PF13465.6 RLN43565.1 - 0.054 14.0 0.6 9.8 6.8 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger double domain Prok-RING_4 PF14447.6 RLN43565.1 - 0.078 12.9 0.4 14 5.6 0.1 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF4201 PF13870.6 RLN43566.1 - 9.4e-37 126.4 26.4 9.4e-37 126.4 26.4 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) Ras PF00071.22 RLN43567.1 - 7.5e-44 149.2 0.3 1.7e-43 148.0 0.3 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RLN43567.1 - 1.4e-25 89.8 0.1 3.7e-25 88.5 0.1 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN43567.1 - 2.5e-06 27.1 0.5 4.1e-05 23.1 0.5 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RLN43567.1 - 0.00012 22.1 0.0 0.29 11.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 RLN43567.1 - 0.0013 18.1 0.2 0.006 16.0 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 RLN43567.1 - 0.0078 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 RLN43567.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase EF-hand_1 PF00036.32 RLN43568.1 - 1.2e-18 65.2 11.2 2e-06 26.9 1.1 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RLN43568.1 - 1.9e-15 57.1 5.3 3.3e-07 30.6 0.1 4.2 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN43568.1 - 3.8e-13 48.2 7.7 0.0051 16.6 0.4 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 RLN43568.1 - 6.6e-11 41.2 11.6 2e-05 23.8 0.6 5.1 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 RLN43568.1 - 2e-10 40.3 8.0 0.0022 17.8 0.1 4.6 4 0 0 4 4 4 3 EF-hand domain pair Ribosomal_L21e PF01157.18 RLN43568.1 - 0.049 13.5 0.7 11 6.0 0.1 2.7 2 0 0 2 2 2 0 Ribosomal protein L21e SH3_4 PF06347.13 RLN43568.1 - 0.13 12.1 0.6 5.7 6.9 0.2 2.7 2 0 0 2 2 2 0 Bacterial SH3 domain EF-hand_4 PF12763.7 RLN43568.1 - 0.16 11.9 2.2 18 5.4 0.0 3.4 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand WD40 PF00400.32 RLN43569.1 - 3.6e-13 49.7 24.7 0.00011 22.9 0.6 7.8 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN43569.1 - 2.9e-10 40.3 5.0 0.042 14.2 0.0 6.5 4 1 5 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 RLN43569.1 - 0.025 12.6 0.1 7.6 4.4 0.0 3.3 2 1 1 3 3 3 0 IKI3 family DPPIV_N PF00930.21 RLN43569.1 - 0.031 13.0 0.1 6.5 5.4 0.0 3.6 4 0 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Vps16_N PF04841.13 RLN43569.1 - 0.059 12.1 0.0 0.27 9.9 0.0 2.0 2 0 0 2 2 2 0 Vps16, N-terminal region NAD_binding_9 PF13454.6 RLN43569.1 - 0.12 12.4 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding CDT1 PF08839.11 RLN43571.1 - 1.3e-18 67.9 1.0 3.4e-18 66.5 0.1 2.0 2 0 0 2 2 2 1 DNA replication factor CDT1 like CDT1_C PF16679.5 RLN43571.1 - 1.8e-11 44.3 7.8 1.7e-10 41.2 1.2 3.1 2 1 1 3 3 3 2 DNA replication factor Cdt1 C-terminal domain DUF922 PF06037.11 RLN43571.1 - 0.0072 16.1 0.0 0.15 11.8 0.0 2.5 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF922) SAM_1 PF00536.30 RLN43572.1 - 6.5e-06 26.5 0.1 2.9e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RLN43572.1 - 0.00012 22.1 0.0 0.00028 20.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) KAAG1 PF15354.6 RLN43572.1 - 0.19 12.3 1.8 0.39 11.3 0.1 2.3 3 0 0 3 3 3 0 Kidney-associated antigen 1 DUF3306 PF11748.8 RLN43572.1 - 0.29 12.0 6.3 0.41 11.5 1.8 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3306) Citrate_bind PF16114.5 RLN43573.1 - 1.5e-89 298.2 0.0 2.8e-89 297.3 0.0 1.5 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 RLN43573.1 - 3.5e-24 85.6 0.1 1.3e-21 77.1 0.1 2.9 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 RLN43573.1 - 1.9e-14 53.8 0.1 4.4e-14 52.6 0.1 1.7 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 RLN43573.1 - 1.3e-06 29.0 0.0 4.6e-06 27.2 0.0 2.1 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 RLN43573.1 - 0.031 14.1 0.5 0.083 12.7 0.0 2.1 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain Aldedh PF00171.22 RLN43574.1 - 1.4e-18 66.6 0.0 1.7e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SDF PF00375.18 RLN43586.1 - 1.4e-59 202.1 68.3 5.5e-44 150.8 31.3 2.6 2 1 0 2 2 2 2 Sodium:dicarboxylate symporter family CPBP PF02517.16 RLN43587.1 - 1.9e-13 50.6 3.3 1.9e-13 50.6 3.3 2.7 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease ABC2_membrane PF01061.24 RLN43588.1 - 5.2e-48 163.3 59.2 2.4e-34 118.6 30.4 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN43588.1 - 8.5e-40 136.4 0.2 1.7e-20 74.0 0.1 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN43588.1 - 1.4e-07 31.6 0.0 0.058 13.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN43588.1 - 3.3e-07 30.8 1.1 0.013 15.9 0.2 3.0 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 RLN43588.1 - 3.9e-07 30.1 0.5 0.0048 16.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 RLN43588.1 - 2.7e-06 27.0 4.9 0.015 15.0 0.9 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN43588.1 - 3.9e-05 23.9 0.1 0.14 12.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN43588.1 - 0.00041 19.7 1.4 0.046 13.0 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin SMC_N PF02463.19 RLN43588.1 - 0.00042 19.8 4.9 1.5 8.2 0.4 4.5 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RLN43588.1 - 0.00059 20.4 1.6 0.097 13.2 0.3 2.3 2 0 0 2 2 2 1 AAA domain PDR_assoc PF08370.11 RLN43588.1 - 0.00071 19.3 1.3 0.00071 19.3 1.3 2.7 2 0 0 2 2 1 1 Plant PDR ABC transporter associated AAA_25 PF13481.6 RLN43588.1 - 0.0009 18.9 0.7 0.41 10.2 0.3 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RLN43588.1 - 0.0013 19.1 0.2 4.2 7.8 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 RLN43588.1 - 0.0022 17.8 0.1 1.5 8.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 RLN43588.1 - 0.0032 17.5 1.2 0.72 9.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 RLN43588.1 - 0.0043 17.6 0.0 1.9 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RLN43588.1 - 0.0047 17.3 0.3 1.6 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 RLN43588.1 - 0.027 14.5 0.3 1.2 9.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.19 RLN43588.1 - 0.033 13.8 1.6 1.5 8.3 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 RLN43588.1 - 0.054 13.4 3.2 5.9 6.8 0.1 2.7 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 RLN43588.1 - 0.057 13.8 0.4 9.6 6.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF2075 PF09848.9 RLN43588.1 - 0.064 12.5 0.1 2.3 7.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 RLN43588.1 - 0.065 13.1 0.1 39 4.0 0.0 3.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea ABC_ATPase PF09818.9 RLN43588.1 - 0.071 11.9 0.5 1.1 8.0 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Ploopntkinase3 PF18751.1 RLN43588.1 - 0.081 12.8 0.5 1 9.3 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF2378 PF09536.10 RLN43588.1 - 0.11 12.4 0.0 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2378) AAA_33 PF13671.6 RLN43588.1 - 0.14 12.3 1.2 16 5.7 0.4 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RLN43588.1 - 0.18 11.5 2.1 15 5.2 0.7 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 RLN43588.1 - 0.26 10.4 0.6 0.52 9.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 RLN43588.1 - 0.27 11.0 1.8 4.5 7.0 0.5 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 RLN43588.1 - 0.3 11.2 5.0 3.8 7.5 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_28 PF13521.6 RLN43588.1 - 0.38 11.0 2.5 30 4.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain PDR_CDR PF06422.12 RLN43588.1 - 1 9.3 8.3 0.12 12.3 0.3 2.9 2 0 0 2 2 2 0 CDR ABC transporter Aminotran_1_2 PF00155.21 RLN43593.1 - 2.7e-79 267.0 1.0 7.5e-79 265.5 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 RLN43593.1 - 1.2e-05 24.0 0.0 2.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 RLN43593.1 - 7.2e-05 21.9 0.0 0.00014 20.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Preseq_ALAS PF09029.10 RLN43593.1 - 0.01 16.3 3.8 0.025 15.1 3.8 1.6 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence AAA_13 PF13166.6 RLN43598.1 - 0.39 9.3 5.6 0.6 8.7 5.6 1.2 1 0 0 1 1 1 0 AAA domain Cys_Met_Meta_PP PF01053.20 RLN43599.1 - 7.8e-34 116.8 0.0 1.1e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 RLN43599.1 - 1.1e-06 28.1 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 RLN43599.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Arm PF00514.23 RLN43601.1 - 5.9e-48 159.5 3.3 2.1e-08 33.9 0.0 9.2 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN43601.1 - 7.2e-12 45.5 15.5 0.12 12.9 0.0 7.4 3 2 6 9 9 9 7 HEAT-like repeat HEAT PF02985.22 RLN43601.1 - 7e-11 41.4 6.4 0.095 13.0 0.0 8.3 9 0 0 9 9 9 1 HEAT repeat HEAT_2 PF13646.6 RLN43601.1 - 1.5e-09 38.1 22.0 0.0017 18.7 5.4 4.2 3 2 1 4 4 4 3 HEAT repeats Atx10homo_assoc PF09759.9 RLN43601.1 - 1.5e-07 31.3 0.2 0.0035 17.3 0.0 4.5 3 2 1 5 5 5 2 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 RLN43601.1 - 5.8e-06 26.5 28.9 2.2 9.2 0.0 8.7 9 0 0 9 9 8 2 PBS lyase HEAT-like repeat RPAP1_C PF08620.10 RLN43601.1 - 5.3e-05 23.2 0.1 5.5 7.2 0.0 4.9 5 0 0 5 5 5 2 RPAP1-like, C-terminal V-ATPase_H_N PF03224.14 RLN43601.1 - 0.00017 21.0 0.0 0.064 12.5 0.0 2.8 2 1 0 2 2 2 1 V-ATPase subunit H DUF4800 PF16057.5 RLN43601.1 - 0.0015 17.9 0.0 0.58 9.4 0.0 3.2 3 1 1 4 4 4 1 Domain of unknown function (DUF4800) Arm_2 PF04826.13 RLN43601.1 - 0.0015 18.0 0.0 1.4 8.3 0.0 3.4 1 1 1 2 2 2 2 Armadillo-like Aconitase_B_N PF11791.8 RLN43601.1 - 0.057 13.5 0.6 2.9 8.0 0.0 3.7 3 2 1 4 4 4 0 Aconitate B N-terminal domain Arylsulfotran_N PF17425.2 RLN43601.1 - 0.13 12.3 0.0 54 3.9 0.0 3.9 5 0 0 5 5 5 0 Arylsulfotransferase Ig-like domain Csc2 PF18320.1 RLN43601.1 - 0.16 10.9 0.0 0.55 9.1 0.0 1.8 2 0 0 2 2 2 0 Csc2 Crispr Succ_CoA_lig PF13607.6 RLN43601.1 - 1.2 8.9 9.8 15 5.4 0.2 5.4 1 1 7 8 8 8 0 Succinyl-CoA ligase like flavodoxin domain FOXP-CC PF16159.5 RLN43602.1 - 0.16 12.6 1.1 0.85 10.3 0.0 2.6 2 1 1 3 3 3 0 FOXP coiled-coil domain T2SSM_b PF10741.9 RLN43602.1 - 0.36 10.7 2.9 0.22 11.4 0.4 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b DUF2937 PF11157.8 RLN43602.1 - 4.3 7.0 5.6 12 5.6 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) BAF1_ABF1 PF04684.13 RLN43602.1 - 6 5.8 9.4 0.45 9.5 1.5 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Sugar_tr PF00083.24 RLN43620.1 - 1.4e-25 90.1 22.1 3.2e-25 88.9 22.1 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN43620.1 - 1.5e-09 37.2 16.5 1.5e-09 37.2 16.5 3.9 1 1 3 4 4 4 2 Major Facilitator Superfamily Glucan_synthase PF02364.15 RLN43620.1 - 0.0002 19.7 0.4 0.00034 18.9 0.4 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component HECT PF00632.25 RLN43621.1 - 1.1e-40 140.0 0.0 1.3e-40 139.8 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) APC_N_CC PF16689.5 RLN43622.1 - 0.023 14.8 1.5 0.079 13.0 1.5 1.9 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain Polyketide_cyc2 PF10604.9 RLN43622.1 - 0.047 14.0 0.5 0.32 11.2 0.1 2.3 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport bZIP_1 PF00170.21 RLN43622.1 - 0.69 10.0 14.3 1.4 9.1 1.1 2.6 2 0 0 2 2 2 0 bZIP transcription factor DUF4391 PF14335.6 RLN43622.1 - 1.4 8.6 6.4 18 4.9 1.1 3.2 2 2 1 4 4 4 0 Domain of unknown function (DUF4391) bZIP_2 PF07716.15 RLN43622.1 - 7.7 6.7 11.7 3 8.0 3.8 2.9 2 0 0 2 2 2 0 Basic region leucine zipper FYVE PF01363.21 RLN43623.1 - 0.0001 22.4 4.7 0.00021 21.3 4.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger C1_1 PF00130.22 RLN43623.1 - 0.053 13.4 1.7 0.12 12.3 1.7 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 RLN43623.1 - 0.23 11.7 4.1 0.28 11.4 3.3 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger Peptidase_M16_C PF05193.21 RLN43638.1 - 1.9e-34 119.3 0.0 3.1e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 RLN43638.1 - 7.9e-25 87.6 0.0 6.3e-21 74.9 0.0 2.8 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) DUF4658 PF15555.6 RLN43639.1 - 0.053 13.6 0.3 0.062 13.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) cNMP_binding PF00027.29 RLN43640.1 - 1.8e-42 143.3 2.1 1.9e-11 43.9 0.0 5.1 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN43640.1 - 2e-32 112.4 38.6 7.9e-13 48.2 1.6 4.6 4 0 0 4 4 4 4 Ion transport protein DUF572 PF04502.13 RLN43641.1 - 0.67 9.5 32.7 0.96 9.0 32.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) PseudoU_synth_1 PF01416.20 RLN43642.1 - 5.6e-16 58.9 0.1 1e-13 51.7 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.9 RLN43642.1 - 0.011 15.6 0.0 0.03 14.1 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Ion_trans PF00520.31 RLN43643.1 - 1.1e-31 110.0 16.4 1.6e-31 109.4 16.4 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RLN43643.1 - 3.4e-13 49.4 3.1 3.4e-13 49.4 3.1 2.8 3 0 0 3 3 3 1 Ion channel EF-hand_1 PF00036.32 RLN43643.1 - 0.02 14.4 1.2 0.02 14.4 1.2 2.1 2 0 0 2 2 2 0 EF hand HTH_Bact PF18768.1 RLN43643.1 - 0.027 14.1 0.1 0.063 12.9 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix bacterial domain EF-hand_5 PF13202.6 RLN43643.1 - 1 9.0 2.8 0.7 9.5 0.6 1.9 2 0 0 2 2 2 0 EF hand DnaJ PF00226.31 RLN43644.1 - 5.2e-16 58.5 0.3 1.2e-09 38.2 0.2 2.3 2 0 0 2 2 2 2 DnaJ domain zf-CSL PF05207.13 RLN43644.1 - 9e-13 47.7 0.4 9e-13 47.7 0.4 1.7 2 0 0 2 2 2 1 CSL zinc finger Exonuc_VIII PF06630.11 RLN43644.1 - 0.041 13.7 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII AKAP95 PF04988.12 RLN43644.1 - 0.14 12.4 0.2 0.92 9.7 0.2 2.0 1 1 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) ATP-synt_S1 PF05827.12 RLN43645.1 - 0.045 13.6 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) MMR_HSR1 PF01926.23 RLN43645.1 - 0.075 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF1196 PF06709.11 RLN43645.1 - 0.085 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1196) zf-TAZ PF02135.16 RLN43647.1 - 0.16 12.4 0.7 0.35 11.4 0.7 1.5 1 0 0 1 1 1 0 TAZ zinc finger RRM_1 PF00076.22 RLN43648.1 - 4.6e-17 61.6 0.0 7.3e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SWIRM-assoc_2 PF16496.5 RLN43648.1 - 0.069 12.0 1.4 0.1 11.4 1.4 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal RRM_5 PF13893.6 RLN43648.1 - 0.097 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Steroid_dh PF02544.16 RLN43649.1 - 6.9e-48 162.4 0.3 1.4e-47 161.4 0.1 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 RLN43649.1 - 2.5e-08 33.7 0.0 4.5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 RLN43649.1 - 5e-05 23.6 0.2 0.00012 22.4 0.2 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase RskA PF10099.9 RLN43649.1 - 0.025 14.9 17.3 0.03 14.6 11.6 3.3 1 1 1 2 2 2 0 Anti-sigma-K factor rskA GTP_EFTU PF00009.27 RLN43649.1 - 0.035 13.6 0.0 0.035 13.6 0.0 2.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Ank_2 PF12796.7 RLN43652.1 - 3.9e-25 88.2 3.7 1.9e-07 31.5 0.1 5.8 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN43652.1 - 1e-24 86.6 0.7 0.0048 17.4 0.0 6.8 5 1 1 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN43652.1 - 2.1e-18 66.1 4.9 0.0011 19.2 0.2 6.5 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 RLN43652.1 - 3.5e-17 62.0 12.9 0.15 12.6 0.0 9.0 10 0 0 10 10 10 5 Ankyrin repeat Ank_3 PF13606.6 RLN43652.1 - 6.2e-16 56.9 5.6 0.071 13.7 0.0 9.2 10 0 0 10 10 10 3 Ankyrin repeat PA_decarbox PF05870.11 RLN43653.1 - 8.7e-09 35.2 0.1 1.1e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) ABC_membrane PF00664.23 RLN43666.1 - 1.1e-54 185.9 3.4 1.7e-54 185.4 3.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN43666.1 - 0.00056 20.4 0.2 0.001 19.6 0.2 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 RLN43666.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 RLN43666.1 - 0.057 13.2 0.2 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Shugoshin_C PF07557.11 RLN43666.1 - 0.9 9.4 2.0 11 6.0 0.3 2.4 2 0 0 2 2 2 0 Shugoshin C terminus DUF4969 PF16339.5 RLN43672.1 - 0.0019 18.5 1.2 0.0019 18.5 1.2 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4969) Reprolysin_5 PF13688.6 RLN43672.1 - 0.0067 16.6 0.0 0.0067 16.6 0.0 3.1 2 1 0 3 3 3 1 Metallo-peptidase family M12 BNIP3 PF06553.12 RLN43672.1 - 0.15 11.7 2.9 0.62 9.7 0.3 2.1 1 1 1 2 2 2 0 BNIP3 Reprolysin_3 PF13582.6 RLN43672.1 - 0.47 11.0 0.1 0.47 11.0 0.1 2.6 3 0 0 3 3 3 0 Metallo-peptidase family M12B Reprolysin-like DUF966 PF06136.13 RLN43672.1 - 1.2 8.8 7.6 1.5 8.5 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SWI-SNF_Ssr4 PF08549.10 RLN43672.1 - 3.7 6.1 11.6 5.1 5.6 11.6 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) RAP1 PF07218.11 RLN43672.1 - 7.9 4.6 9.0 10 4.3 9.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_S8 PF00082.22 RLN43673.1 - 2.4e-46 158.4 3.9 2.4e-46 158.4 3.9 2.0 1 1 1 2 2 2 2 Subtilase family Retrotrans_gag PF03732.17 RLN43674.1 - 0.013 15.8 0.1 0.013 15.7 0.1 1.1 1 0 0 1 1 1 0 Retrotransposon gag protein UPF0172 PF03665.13 RLN43677.1 - 1.8e-48 165.1 0.0 2.1e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 RLN43677.1 - 0.043 13.8 0.0 0.09 12.8 0.0 1.5 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DPM2 PF07297.12 RLN43678.1 - 5.8e-19 68.2 0.4 6.6e-19 68.0 0.4 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) TMEM154 PF15102.6 RLN43678.1 - 0.093 12.6 0.0 0.094 12.6 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family Alpha-amylase PF00128.24 RLN43679.1 - 0.49 9.9 2.0 0.64 9.5 2.0 1.2 1 0 0 1 1 1 0 Alpha amylase, catalytic domain HBS1_N PF08938.10 RLN43679.1 - 0.51 10.7 6.9 0.17 12.2 1.0 2.6 2 1 0 2 2 2 0 HBS1 N-terminus Atg14 PF10186.9 RLN43679.1 - 2.7 7.0 7.2 3.7 6.5 7.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Mito_carr PF00153.27 RLN43680.1 - 5e-67 221.9 5.4 1.4e-22 79.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Topo-VIb_trans PF09239.11 RLN43681.1 - 0.00022 21.1 0.0 0.00038 20.3 0.0 1.4 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer TGase_elicitor PF16683.5 RLN43682.1 - 2.4e-177 589.2 1.3 2.8e-177 588.9 1.3 1.0 1 0 0 1 1 1 1 Transglutaminase elicitor Cupin_8 PF13621.6 RLN43683.1 - 7.1e-20 71.8 0.4 1.5e-19 70.8 0.0 1.6 2 0 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 RLN43683.1 - 3.2e-19 69.4 0.0 7.3e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Coilin_N PF15862.5 RLN43683.1 - 0.29 10.9 4.5 0.53 10.1 4.5 1.4 1 0 0 1 1 1 0 Coilin N-terminus Gal-bind_lectin PF00337.22 RLN43684.1 - 3.2e-13 49.4 0.0 5.3e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Galactoside-binding lectin RRM_1 PF00076.22 RLN43684.1 - 4.7e-13 48.8 0.0 3.4e-12 46.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vel1p PF10339.9 RLN43685.1 - 0.024 14.0 0.4 0.033 13.6 0.4 1.2 1 0 0 1 1 1 0 Yeast-specific zinc responsive SQAPI PF16845.5 RLN43685.1 - 0.029 14.7 0.1 0.25 11.7 0.1 2.0 1 1 0 1 1 1 0 Aspartic acid proteinase inhibitor Cystatin PF00031.21 RLN43685.1 - 0.063 13.6 0.1 0.095 13.0 0.1 1.4 1 1 0 1 1 1 0 Cystatin domain SNN_transmemb PF09049.10 RLN43685.1 - 0.18 11.8 2.4 0.96 9.4 0.6 2.3 2 0 0 2 2 2 0 Stannin transmembrane UPF0113 PF03657.13 RLN43686.1 - 2.8e-24 85.2 0.0 7.9e-23 80.5 0.0 2.3 2 0 0 2 2 2 1 UPF0113 PUA domain UPF0113_N PF17833.1 RLN43686.1 - 8.2e-24 84.0 0.5 2e-23 82.7 0.3 1.7 2 0 0 2 2 2 1 UPF0113 Pre-PUA domain AAA_16 PF13191.6 RLN43687.1 - 0.071 13.5 0.1 0.22 11.9 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 RLN43688.1 - 2.9e-43 147.5 0.0 4.9e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RLN43688.1 - 1.2e-08 34.7 0.1 2.6e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 RLN43688.1 - 1e-05 26.0 0.7 0.0003 21.2 0.3 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RLN43688.1 - 1.2e-05 25.6 0.4 0.0023 18.2 0.4 2.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 RLN43688.1 - 1.5e-05 24.8 0.0 2.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 RLN43688.1 - 8.6e-05 22.6 0.1 0.00063 19.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RLN43688.1 - 9.3e-05 22.6 0.0 0.00019 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 RLN43688.1 - 0.00024 20.9 0.0 0.00059 19.6 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RLN43688.1 - 0.00031 20.9 0.0 0.00057 20.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 RLN43688.1 - 0.00031 20.0 0.0 0.00058 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 RLN43688.1 - 0.0007 18.9 0.1 0.0014 17.9 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 RLN43688.1 - 0.0047 16.4 0.0 0.014 14.9 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 RLN43688.1 - 0.0088 16.6 0.1 0.023 15.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 RLN43688.1 - 0.009 15.7 0.0 0.034 13.8 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain TsaE PF02367.17 RLN43688.1 - 0.032 14.2 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 RLN43688.1 - 0.032 13.8 0.1 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 RLN43688.1 - 0.037 13.5 0.1 0.081 12.4 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 RLN43688.1 - 0.038 14.0 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 RLN43688.1 - 0.045 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 RLN43688.1 - 0.065 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 RLN43688.1 - 0.068 13.1 0.2 0.29 11.0 0.0 2.0 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.22 RLN43688.1 - 0.14 12.6 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Cytidylate_kin PF02224.18 RLN43688.1 - 0.14 11.9 0.1 0.28 10.9 0.1 1.5 1 0 0 1 1 1 0 Cytidylate kinase Pyrid_oxidase_2 PF13883.6 RLN43689.1 - 1.1e-25 90.5 0.2 3.4e-25 89.0 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase INCA1 PF15142.6 RLN43689.1 - 0.077 13.0 0.2 2 8.4 0.0 3.1 3 1 1 4 4 4 0 INCA1 Amidohydro_1 PF01979.20 RLN43692.1 - 3.6e-18 66.0 0.1 4.9e-18 65.6 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 RLN43692.1 - 0.00023 21.0 0.0 0.00045 20.1 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase zf-TRAF_2 PF15965.5 RLN43693.1 - 9.6e-08 32.4 1.0 0.0011 19.4 0.1 2.4 2 0 0 2 2 2 2 TRAF-like zinc-finger PAP_assoc PF03828.19 RLN43693.1 - 1.4e-05 25.2 0.0 0.0017 18.5 0.0 2.7 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 RLN43693.1 - 0.012 15.9 0.1 0.035 14.4 0.0 1.9 2 0 0 2 2 2 0 Nucleotidyltransferase domain zf-TRAF PF02176.18 RLN43693.1 - 0.021 15.5 5.0 0.44 11.3 0.2 2.9 3 0 0 3 3 3 0 TRAF-type zinc finger Sina PF03145.16 RLN43693.1 - 0.042 13.8 1.4 4.1 7.3 0.1 2.3 2 0 0 2 2 2 0 Seven in absentia protein family Polbeta PF18765.1 RLN43693.1 - 0.063 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase DEAD_2 PF06733.15 RLN43694.1 - 3.7e-50 170.0 0.3 9.5e-50 168.6 0.1 1.9 2 0 0 2 2 2 1 DEAD_2 HBB PF06777.11 RLN43694.1 - 4.4e-36 124.4 1.4 4.9e-30 104.6 0.5 3.0 2 1 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 RLN43694.1 - 1.1e-24 87.5 0.0 2.3e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 RLN43694.1 - 7.8e-07 29.3 0.1 8.3e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RLN43694.1 - 0.00015 21.6 0.2 0.011 15.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 RLN43694.1 - 0.024 13.4 0.0 2.3 6.9 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain DUF2075 PF09848.9 RLN43694.1 - 0.036 13.3 0.0 3.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 RLN43694.1 - 0.037 14.3 1.1 4 7.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 RLN43694.1 - 0.15 11.5 0.2 3.1 7.2 0.0 2.5 3 0 0 3 3 3 0 PhoH-like protein Ank_2 PF12796.7 RLN43695.1 - 9.5e-20 71.0 0.0 2.5e-05 24.8 0.0 5.1 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN43695.1 - 1.1e-16 60.9 2.3 0.00026 21.5 0.2 7.5 6 3 2 8 8 8 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN43695.1 - 1.8e-14 53.6 9.0 0.0064 16.8 0.0 9.0 5 2 5 10 10 10 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN43695.1 - 1.2e-10 40.7 3.4 0.92 10.3 0.0 8.6 11 0 0 11 11 11 2 Ankyrin repeat DUF249 PF03158.13 RLN43695.1 - 0.0073 16.0 0.1 0.84 9.3 0.0 2.4 2 0 0 2 2 2 1 Multigene family 530 protein Ank PF00023.30 RLN43695.1 - 0.064 13.7 1.0 65 4.2 0.0 5.0 5 2 0 5 5 5 0 Ankyrin repeat Ank_4 PF13637.6 RLN43696.1 - 6.4e-33 112.7 11.7 1.8e-06 28.4 0.2 9.0 5 2 6 11 11 11 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN43696.1 - 1e-28 99.7 2.4 2e-05 25.1 0.0 5.9 2 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN43696.1 - 5.8e-26 90.2 17.1 0.0072 16.6 0.2 12.8 3 2 11 14 14 14 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN43696.1 - 1.3e-11 43.6 4.9 8.8 7.3 0.0 11.2 11 1 0 12 12 12 2 Ankyrin repeat Ank PF00023.30 RLN43696.1 - 0.0002 21.6 1.4 1.8e+02 2.8 0.0 7.8 6 2 2 8 8 8 0 Ankyrin repeat Peripla_BP_5 PF13433.6 RLN43696.1 - 0.047 12.7 0.0 0.18 10.8 0.0 1.9 2 0 0 2 2 2 0 Periplasmic binding protein domain TGBp3 PF02495.17 RLN43696.1 - 0.39 10.4 1.9 2.4e+02 1.5 0.0 4.5 4 1 1 5 5 5 0 Triple gene block 3 Ank_2 PF12796.7 RLN43697.1 - 5.1e-32 110.3 3.4 1.4e-05 25.6 0.4 6.6 4 2 1 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN43697.1 - 9.5e-30 102.6 16.5 0.00032 21.2 0.1 11.0 5 4 6 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN43697.1 - 4.2e-19 68.4 24.9 0.0094 16.3 0.1 13.0 9 3 6 15 15 15 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN43697.1 - 4.3e-15 54.3 8.8 6.4 7.7 0.0 13.8 16 0 0 16 16 16 2 Ankyrin repeat DUF249 PF03158.13 RLN43697.1 - 0.00021 21.0 1.1 1.2 8.8 0.0 3.9 3 1 1 4 4 4 2 Multigene family 530 protein Ank PF00023.30 RLN43697.1 - 0.0014 19.0 7.5 34 5.1 0.1 8.7 7 1 1 8 8 8 0 Ankyrin repeat Ank_2 PF12796.7 RLN43698.1 - 1e-39 134.9 36.5 1.8e-09 38.0 0.8 6.9 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN43698.1 - 1.4e-33 114.8 22.6 3.3e-06 27.5 0.1 11.0 7 3 6 13 13 13 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN43698.1 - 2.2e-25 88.4 26.5 0.0013 19.0 0.2 13.5 9 3 5 14 14 14 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN43698.1 - 2.3e-18 64.4 15.0 0.63 10.8 0.1 13.4 13 2 2 15 15 15 4 Ankyrin repeat Ank PF00023.30 RLN43698.1 - 5.4e-06 26.6 19.0 4.5 7.9 0.5 10.7 7 3 1 8 8 8 2 Ankyrin repeat Tet_JBP PF12851.7 RLN43698.1 - 0.0029 17.0 0.0 0.0072 15.7 0.0 1.7 2 0 0 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily DUF249 PF03158.13 RLN43698.1 - 0.0078 15.9 1.1 0.36 10.5 0.0 3.6 4 1 0 4 4 4 1 Multigene family 530 protein Phosphonate-bd PF12974.7 RLN43698.1 - 0.085 12.4 0.3 0.97 9.0 0.1 2.4 2 1 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein PDZ_6 PF17820.1 RLN43706.1 - 3.8e-07 29.8 0.2 7e-07 29.0 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RLN43706.1 - 0.0002 21.6 0.1 0.00083 19.7 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 RLN43706.1 - 0.048 14.0 0.0 0.15 12.4 0.1 1.8 2 0 0 2 2 2 0 PDZ domain KASH_CCD PF14662.6 RLN43707.1 - 6e-05 23.0 7.4 6e-05 23.0 7.4 5.8 2 1 3 5 5 5 2 Coiled-coil region of CCDC155 or KASH DUF724 PF05266.14 RLN43707.1 - 0.0057 16.5 9.4 0.0057 16.5 9.4 5.7 2 1 2 5 5 5 2 Protein of unknown function (DUF724) YabA PF06156.13 RLN43707.1 - 0.073 13.7 50.6 0.37 11.4 0.4 6.9 3 1 3 7 7 7 0 Initiation control protein YabA DUF1664 PF07889.12 RLN43707.1 - 0.11 12.6 38.9 0.027 14.5 2.3 5.5 4 1 1 6 6 6 0 Protein of unknown function (DUF1664) HALZ PF02183.18 RLN43707.1 - 0.16 12.2 0.1 0.16 12.2 0.1 8.4 9 1 1 10 10 10 0 Homeobox associated leucine zipper VGPC1_C PF16799.5 RLN43707.1 - 0.48 10.4 6.5 17 5.5 0.2 4.6 4 0 0 4 4 4 0 C-terminal membrane-localisation domain of ion-channel, VCN1 YojJ PF10372.9 RLN43707.1 - 2.4 8.3 7.0 18 5.5 0.0 4.3 3 2 1 4 4 4 0 Bacterial membrane-spanning protein N-terminus Tropomyosin_1 PF12718.7 RLN43707.1 - 8 6.6 81.0 1.1 9.4 26.5 5.7 2 1 4 6 6 6 0 Tropomyosin like LRR_4 PF12799.7 RLN43711.1 - 0.00067 20.0 0.7 4.1 8.0 0.0 3.7 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) KIX_2 PF16987.5 RLN43711.1 - 0.012 15.6 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 KIX domain LRR_8 PF13855.6 RLN43711.1 - 0.3 10.9 3.0 34 4.3 0.3 4.1 3 1 1 4 4 4 0 Leucine rich repeat SNARE PF05739.19 RLN43712.1 - 1.3e-11 44.3 0.1 2.9e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 RLN43712.1 - 9.4e-07 28.7 4.5 0.0011 18.7 0.2 2.1 2 0 0 2 2 2 2 Syntaxin Baculo_PEP_C PF04513.12 RLN43712.1 - 0.0066 16.5 3.3 0.38 10.8 0.7 2.2 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Hrs_helical PF12210.8 RLN43713.1 - 0.043 14.3 0.6 0.048 14.2 0.6 1.1 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Myosin_head PF00063.21 RLN43714.1 - 2.6e-11 42.5 0.1 2e-06 26.3 0.3 2.2 1 1 1 2 2 2 2 Myosin head (motor domain) Attractin PF08037.11 RLN43714.1 - 0.033 14.2 0.1 1.9 8.6 0.1 2.5 2 0 0 2 2 2 0 Attractin family Lsr2 PF11774.8 RLN43714.1 - 0.12 12.5 0.0 6.9 6.9 0.0 2.7 3 0 0 3 3 3 0 Lsr2 Phage_P2_GpE PF06528.12 RLN43714.1 - 0.14 11.7 0.3 0.49 10.0 0.0 2.1 2 0 0 2 2 2 0 Phage P2 GpE HIG_1_N PF04588.13 RLN43715.1 - 8.1e-19 67.6 3.2 1.1e-18 67.2 3.2 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Yip1 PF04893.17 RLN43715.1 - 0.0018 18.0 0.0 0.0019 17.9 0.0 1.0 1 0 0 1 1 1 1 Yip1 domain FIST PF08495.10 RLN43715.1 - 0.13 12.3 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 FIST N domain DUF883 PF05957.13 RLN43715.1 - 0.14 12.8 2.1 0.17 12.5 0.1 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4604 PF15377.6 RLN43724.1 - 0.15 12.5 22.9 0.4 11.1 22.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) Raftlin PF15250.6 RLN43724.1 - 0.36 9.5 4.6 0.41 9.3 4.6 1.0 1 0 0 1 1 1 0 Raftlin PRTP PF01366.18 RLN43724.1 - 2 6.4 4.5 2.3 6.2 4.5 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein CDC45 PF02724.14 RLN43724.1 - 3.1 6.0 12.6 3.9 5.6 12.6 1.0 1 0 0 1 1 1 0 CDC45-like protein CTC1 PF15489.6 RLN43725.1 - 2.4e-07 28.7 0.0 4e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 CST, telomere maintenance, complex subunit CTC1 Nuc_sug_transp PF04142.15 RLN43726.1 - 2.7e-102 342.1 10.4 3.7e-102 341.7 10.4 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 RLN43726.1 - 7.2e-09 35.3 8.6 1e-08 34.8 8.6 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 RLN43726.1 - 6.1e-06 26.5 24.1 0.0034 17.5 6.1 2.6 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 RLN43726.1 - 0.042 13.1 13.4 0.091 12.0 13.2 1.7 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport DUF4229 PF14012.6 RLN43726.1 - 1.8 8.7 9.2 3.1 8.0 2.9 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) BRCT PF00533.26 RLN43727.1 - 2.6e-12 46.9 0.0 7e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 RLN43727.1 - 4.7e-09 36.8 0.1 1.7e-08 34.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 RLN43727.1 - 3e-06 27.1 0.0 6.6e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 RLN43727.1 - 0.00016 21.7 0.9 0.00016 21.7 0.9 2.8 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 RLN43727.1 - 0.0012 19.3 0.0 0.0012 19.3 0.0 2.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 RLN43727.1 - 0.0019 18.2 0.3 0.022 14.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 RLN43727.1 - 0.0033 18.0 0.0 0.0033 18.0 0.0 2.8 2 1 1 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 RLN43727.1 - 0.0057 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 RLN43727.1 - 0.0062 16.7 0.4 0.021 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 RLN43727.1 - 0.0075 16.2 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 NTPase TsaE PF02367.17 RLN43727.1 - 0.025 14.6 0.0 0.062 13.3 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 RLN43727.1 - 0.034 14.4 0.1 0.096 12.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain PTCB-BRCT PF12738.7 RLN43727.1 - 0.038 14.0 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain AAA_7 PF12775.7 RLN43727.1 - 0.051 13.1 0.1 0.13 11.8 0.1 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 RLN43727.1 - 0.053 13.9 0.1 0.26 11.7 0.0 2.3 2 0 0 2 2 1 0 RNA helicase AAA_22 PF13401.6 RLN43727.1 - 0.074 13.3 1.0 0.18 12.1 0.0 2.2 3 0 0 3 3 2 0 AAA domain AAA_17 PF13207.6 RLN43727.1 - 0.14 12.6 0.0 0.14 12.6 0.0 3.5 3 1 0 4 4 3 0 AAA domain ABC_tran PF00005.27 RLN43727.1 - 0.46 11.0 0.1 0.46 11.0 0.1 3.4 2 1 0 3 3 2 0 ABC transporter CDC45 PF02724.14 RLN43727.1 - 0.49 8.6 23.0 0.9 7.8 23.0 1.4 1 0 0 1 1 1 0 CDC45-like protein GREB1 PF15782.5 RLN43727.1 - 0.64 7.1 15.1 6.4 3.8 0.0 2.0 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer AAA_23 PF13476.6 RLN43727.1 - 4.6 7.7 23.0 7.4 7.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain CDK5_activator PF03261.15 RLN43727.1 - 8.4 5.8 15.9 16 4.9 15.9 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein cNMP_binding PF00027.29 RLN43731.1 - 9.7e-13 48.0 0.2 3.8e-08 33.3 0.0 3.6 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN43731.1 - 5.6e-05 22.5 18.2 5.6e-05 22.5 18.2 2.1 2 1 0 2 2 2 1 Ion transport protein BEX PF04538.12 RLN43731.1 - 0.56 10.8 2.3 1.9 9.1 2.3 1.8 1 0 0 1 1 1 0 Brain expressed X-linked like family FYVE PF01363.21 RLN43732.1 - 6.8e-15 55.0 12.7 1.4e-14 54.0 12.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger Rogdi_lz PF10259.9 RLN43732.1 - 0.039 13.4 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein FYVE_2 PF02318.16 RLN43732.1 - 0.21 11.8 8.2 0.49 10.6 8.2 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger DUF4884 PF16225.5 RLN43733.1 - 0.35 11.0 4.0 11 6.1 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4884) Tetraspanin PF00335.20 RLN43734.1 - 2.2e-09 37.4 1.6 5e-09 36.2 1.6 1.7 1 1 0 1 1 1 1 Tetraspanin family Prismane PF03063.20 RLN43734.1 - 0.13 10.9 0.2 0.18 10.5 0.2 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Baculo_p74_N PF08404.10 RLN43734.1 - 0.18 10.9 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal COPI_assoc PF08507.10 RLN43735.1 - 1.5e-08 34.8 6.9 2.3e-08 34.2 6.9 1.2 1 0 0 1 1 1 1 COPI associated protein DUF4059 PF13268.6 RLN43735.1 - 0.11 12.9 0.9 0.35 11.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) AAA PF00004.29 RLN43736.1 - 6.6e-44 149.5 0.0 1.5e-43 148.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 RLN43736.1 - 1.6e-10 40.8 0.1 1e-09 38.2 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 RLN43736.1 - 8.5e-09 35.5 0.1 2.9e-08 33.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RLN43736.1 - 1e-07 32.2 0.1 2.9e-07 30.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 RLN43736.1 - 3.5e-06 26.7 0.0 8.5e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 RLN43736.1 - 1.5e-05 25.5 0.3 0.0022 18.4 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 RLN43736.1 - 0.00011 22.2 0.1 0.013 15.4 0.0 3.0 3 0 0 3 3 3 1 NTPase RuvB_N PF05496.12 RLN43736.1 - 0.00021 21.0 0.0 0.00061 19.6 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RLN43736.1 - 0.00025 21.3 0.7 0.022 15.0 0.7 2.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 RLN43736.1 - 0.00026 20.3 0.0 0.00054 19.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 RLN43736.1 - 0.00056 19.4 0.1 0.0013 18.1 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 RLN43736.1 - 0.00083 18.7 0.0 0.0018 17.6 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 RLN43736.1 - 0.00096 19.7 0.0 0.0027 18.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 RLN43736.1 - 0.0016 18.6 0.1 0.0057 16.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 RLN43736.1 - 0.0022 18.0 0.0 0.029 14.4 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 RLN43736.1 - 0.0023 18.2 0.0 0.0046 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 RLN43736.1 - 0.0036 17.0 0.0 0.0088 15.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 RLN43736.1 - 0.0041 16.6 0.1 0.017 14.7 0.1 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 RLN43736.1 - 0.0049 17.2 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 RLN43736.1 - 0.011 15.4 0.3 0.024 14.3 0.3 1.6 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 RLN43736.1 - 0.013 14.6 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 RLN43736.1 - 0.016 14.9 0.2 0.17 11.6 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 RLN43736.1 - 0.019 14.7 0.2 0.046 13.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 RLN43736.1 - 0.025 14.6 0.0 0.081 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RLN43736.1 - 0.029 14.3 0.1 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 RLN43736.1 - 0.057 13.3 0.1 1.1 9.1 0.0 2.4 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 RLN43736.1 - 0.068 12.6 0.0 1.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA_3 PF07726.11 RLN43736.1 - 0.073 12.9 0.1 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AFG1_ATPase PF03969.16 RLN43736.1 - 0.086 11.7 0.1 0.23 10.3 0.1 1.7 1 1 0 1 1 1 0 AFG1-like ATPase ATPase PF06745.13 RLN43736.1 - 0.11 11.9 0.7 1.2 8.4 0.0 2.6 3 0 0 3 3 3 0 KaiC PhoH PF02562.16 RLN43736.1 - 0.11 12.0 0.1 0.26 10.7 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 RLN43736.1 - 0.13 11.8 2.8 0.5 9.9 0.3 2.3 1 1 1 2 2 2 0 AAA domain HIP1_clath_bdg PF16515.5 RLN43736.1 - 0.17 12.5 0.4 1.8 9.2 0.1 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Dynamin_M PF01031.20 RLN43742.1 - 8.2e-11 41.6 0.0 1.3e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region GED PF02212.18 RLN43742.1 - 3.4e-05 23.9 0.9 6.7e-05 23.0 0.9 1.5 1 0 0 1 1 1 1 Dynamin GTPase effector domain GED PF02212.18 RLN43743.1 - 4.4e-09 36.4 0.1 8e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 Dynamin GTPase effector domain Dynamin_M PF01031.20 RLN43743.1 - 4.3e-08 32.7 0.0 7.5e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region PSD2 PF07624.11 RLN43744.1 - 0.034 13.9 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) Helitron_like_N PF14214.6 RLN43746.1 - 5e-11 43.2 0.1 5e-11 43.2 0.1 2.4 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus RabGAP-TBC PF00566.18 RLN43748.1 - 0.029 14.0 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Pkinase_Tyr PF07714.17 RLN43749.1 - 6e-41 140.4 0.0 8.6e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN43749.1 - 1e-27 97.2 0.0 1.7e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ApoLp-III PF07464.11 RLN43801.1 - 0.0034 17.5 1.8 0.0034 17.5 1.8 2.9 2 2 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) Arnt_C PF18583.1 RLN43801.1 - 0.13 11.8 0.9 0.28 10.8 0.9 1.5 1 0 0 1 1 1 0 Aminoarabinose transferase C-terminal domain DUF948 PF06103.11 RLN43801.1 - 0.27 11.5 0.1 0.27 11.5 0.1 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) ZapB PF06005.12 RLN43801.1 - 9.1 6.8 13.5 0.15 12.6 2.4 3.3 3 0 0 3 3 3 0 Cell division protein ZapB Pyridoxal_deC PF00282.19 RLN43802.1 - 1.2e-07 30.8 0.0 2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain CENP-F_leu_zip PF10473.9 RLN43802.1 - 0.59 10.2 65.7 0.02 14.9 12.8 4.7 1 1 4 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Herpes_Helicase PF02689.14 RLN43803.1 - 0.055 11.4 0.0 0.075 10.9 0.0 1.1 1 0 0 1 1 1 0 Helicase DUF1180 PF06679.12 RLN43803.1 - 3.5 8.0 13.0 34 4.8 8.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Sad1_UNC PF07738.13 RLN43804.1 - 4.3e-28 97.9 0.0 5.8e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.25 RLN43804.1 - 0.015 15.5 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 F5/8 type C domain Ras PF00071.22 RLN43824.1 - 8.5e-40 136.0 0.4 1.1e-39 135.6 0.4 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN43824.1 - 8e-29 100.3 0.2 1.2e-28 99.7 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN43824.1 - 3e-09 36.6 0.1 4.7e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RLN43824.1 - 0.00011 21.6 0.1 0.00015 21.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RLN43824.1 - 0.0013 18.8 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN43824.1 - 0.029 13.9 0.5 0.063 12.8 0.1 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B cobW PF02492.19 RLN43824.1 - 0.031 13.9 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain VHP PF02209.19 RLN43824.1 - 0.042 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Villin headpiece domain PduV-EutP PF10662.9 RLN43824.1 - 0.044 13.5 0.5 0.093 12.5 0.2 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Nucleo_P87 PF07267.11 RLN43824.1 - 0.14 11.0 1.6 0.18 10.6 1.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 YjcZ PF13990.6 RLN43825.1 - 0.038 13.4 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 YjcZ-like protein FYVE_2 PF02318.16 RLN43825.1 - 0.072 13.3 4.8 0.18 12.0 4.8 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 RLN43825.1 - 0.11 12.7 9.7 0.23 11.6 9.7 1.5 1 0 0 1 1 1 0 FYVE zinc finger PTAC PF06130.12 RLN43826.1 - 0.053 13.7 0.1 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Phosphate propanoyltransferase Gam PF06064.11 RLN43826.1 - 0.064 13.5 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Host-nuclease inhibitor protein Gam Ank_2 PF12796.7 RLN43827.1 - 5.4e-34 116.6 10.8 5.2e-08 33.4 0.1 5.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN43827.1 - 6.6e-28 93.7 13.2 0.0013 19.0 0.0 9.5 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 RLN43827.1 - 1.2e-27 95.1 19.9 5.2e-05 23.5 0.1 9.2 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.6 RLN43827.1 - 1.4e-27 95.6 14.5 2.4e-07 31.1 0.0 7.2 4 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN43827.1 - 8.3e-23 80.2 12.1 7e-06 26.2 0.5 6.5 3 2 4 7 7 7 6 Ankyrin repeats (many copies) UCH PF00443.29 RLN43829.1 - 5.9e-68 229.1 0.0 7.9e-68 228.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN43829.1 - 1e-17 64.7 0.1 4.9e-10 39.5 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Plexin_cytopl PF08337.12 RLN43829.1 - 0.11 11.2 0.8 0.18 10.4 0.8 1.3 1 0 0 1 1 1 0 Plexin cytoplasmic RasGAP domain EF-hand_7 PF13499.6 RLN43829.1 - 0.11 13.0 1.1 0.93 10.0 0.3 2.8 2 0 0 2 2 2 0 EF-hand domain pair PPR_2 PF13041.6 RLN43830.1 - 3e-27 94.5 1.6 5.9e-06 26.4 0.0 7.3 3 1 4 7 7 7 5 PPR repeat family PPR PF01535.20 RLN43830.1 - 2.5e-19 68.1 2.7 0.04 14.2 0.0 8.8 10 0 0 10 10 10 5 PPR repeat PPR_3 PF13812.6 RLN43830.1 - 2.7e-18 65.8 0.0 3.5e-07 30.2 0.0 4.6 4 0 0 4 4 4 4 Pentatricopeptide repeat domain PPR_long PF17177.4 RLN43830.1 - 4.8e-12 45.7 3.8 0.00014 21.3 0.1 3.3 1 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP COX5A PF02284.16 RLN43830.1 - 0.0001 22.3 1.2 3.5 7.7 0.0 4.1 2 1 0 4 4 4 2 Cytochrome c oxidase subunit Va PPR_1 PF12854.7 RLN43830.1 - 0.00059 19.5 0.2 5.7 6.7 0.0 4.3 4 0 0 4 4 4 2 PPR repeat RPM2 PF08579.11 RLN43830.1 - 0.0021 18.5 0.2 0.16 12.4 0.1 2.8 2 1 0 2 2 2 1 Mitochondrial ribonuclease P subunit (RPM2) EamA PF00892.20 RLN43832.1 - 1.3e-14 54.6 29.8 1.2e-11 44.9 17.1 2.3 2 1 0 2 2 2 2 EamA-like transporter family EamA PF00892.20 RLN43833.1 - 1e-12 48.4 23.9 3.2e-10 40.3 15.2 2.3 1 1 1 2 2 2 2 EamA-like transporter family TMEM132D_C PF15706.5 RLN43833.1 - 0.17 11.7 2.5 0.14 12.0 0.4 2.0 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term MCM6_C PF18263.1 RLN43880.1 - 2.3e-22 79.2 16.0 3.2e-21 75.6 16.0 2.5 1 1 0 1 1 1 1 MCM6 C-terminal winged-helix domain MLIP PF15274.6 RLN43880.1 - 0.0025 17.7 0.4 0.0034 17.3 0.4 1.2 1 0 0 1 1 1 1 Muscular LMNA-interacting protein DUF4961 PF16328.5 RLN43880.1 - 0.01 15.2 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4961) Tox-GHH PF15636.6 RLN43880.1 - 0.027 14.5 1.0 0.069 13.1 1.0 1.8 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin PGA2 PF07543.12 RLN43880.1 - 0.64 10.0 21.6 0.49 10.4 10.7 2.2 1 1 1 2 2 2 0 Protein trafficking PGA2 JAB PF01398.21 RLN43880.1 - 0.82 9.7 3.7 2.1 8.4 3.3 2.1 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4604 PF15377.6 RLN43880.1 - 5.4 7.4 17.8 0.17 12.3 12.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) PH PF00169.29 RLN43881.1 - 6.1e-10 39.5 0.0 1.3e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 PH domain ACBP PF00887.19 RLN43881.1 - 6.6e-06 26.3 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein FYVE PF01363.21 RLN43881.1 - 4.5e-05 23.5 5.6 8.8e-05 22.6 5.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger IQ_SEC7_PH PF16453.5 RLN43881.1 - 0.066 13.2 0.0 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 PH domain MULE PF10551.9 RLN43882.1 - 6.1e-18 65.0 0.3 1.5e-17 63.7 0.3 1.7 1 0 0 1 1 1 1 MULE transposase domain Anticodon_1 PF08264.13 RLN43890.1 - 1.4e-40 138.7 0.0 2.2e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Val_tRNA-synt_C PF10458.9 RLN43890.1 - 7.8e-10 38.9 2.3 1.9e-09 37.7 2.3 1.7 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm ABC_tran_CTD PF16326.5 RLN43890.1 - 0.17 12.2 1.9 0.54 10.5 1.6 2.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain Glyco_hydro_3 PF00933.21 RLN43891.1 - 8.1e-49 166.7 0.0 1e-48 166.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN43891.1 - 1.5e-29 103.4 0.0 4.7e-29 101.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain DUF2474 PF10617.9 RLN43892.1 - 1.4 8.8 5.2 4.6 7.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2474) LicD PF04991.13 RLN43893.1 - 7.8e-05 22.9 0.0 0.0097 16.1 0.0 2.1 2 0 0 2 2 2 2 LicD family Aa_trans PF01490.18 RLN43894.1 - 1.8e-57 194.9 24.9 2.2e-57 194.6 24.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4212 PF13937.6 RLN43894.1 - 0.028 14.8 0.2 0.028 14.8 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) DUF2401 PF10287.9 RLN43895.1 - 4.6e-59 199.8 0.2 8.3e-59 199.0 0.2 1.4 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 RLN43895.1 - 6.5e-13 48.9 2.4 8.1e-13 48.6 0.1 2.4 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) EFhand_Ca_insen PF08726.10 RLN43896.1 - 0.0022 18.0 0.1 0.0036 17.4 0.1 1.3 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_7 PF13499.6 RLN43896.1 - 0.0033 17.8 0.0 0.0057 17.1 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN43896.1 - 0.0035 17.1 0.0 0.0079 16.1 0.0 1.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 RLN43896.1 - 0.042 13.4 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 EF hand EMG1 PF03587.14 RLN43896.1 - 0.087 12.5 0.0 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 EMG1/NEP1 methyltransferase TPR_1 PF00515.28 RLN43897.1 - 1.2e-14 53.4 0.0 3.4e-06 26.6 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN43897.1 - 8.2e-13 47.4 0.0 2.2e-06 27.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 RLN43897.1 - 6.7e-11 42.7 0.1 2.9e-09 37.4 0.1 2.8 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN43897.1 - 1.4e-08 34.8 1.3 6.8e-07 29.3 0.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN43897.1 - 1.8e-06 28.3 1.2 0.0053 17.5 0.0 4.1 1 1 3 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN43897.1 - 2e-05 24.2 0.0 0.016 14.9 0.0 2.7 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.6 RLN43897.1 - 4e-05 23.7 0.0 0.051 14.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN43897.1 - 4.2e-05 24.0 0.0 0.00026 21.5 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN43897.1 - 0.0001 22.5 0.5 0.017 15.4 0.1 3.3 1 1 3 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN43897.1 - 0.0014 18.7 0.0 0.081 13.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 RLN43897.1 - 0.005 16.5 0.0 1.8 8.2 0.0 2.3 1 1 1 2 2 2 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_20 PF14561.6 RLN43897.1 - 0.0075 16.6 0.0 0.56 10.6 0.0 2.7 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN43897.1 - 0.01 16.4 0.0 0.17 12.6 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HemY_N PF07219.13 RLN43897.1 - 0.054 13.7 0.0 0.35 11.1 0.0 2.2 1 1 1 2 2 2 0 HemY protein N-terminus ANAPC3 PF12895.7 RLN43897.1 - 0.15 12.3 0.0 0.97 9.7 0.0 2.1 2 1 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 ANAPC1 PF12859.7 RLN43897.1 - 0.21 12.1 2.7 0.37 11.3 2.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 LpxB PF02684.15 RLN43937.1 - 2.8e-47 161.4 0.1 2e-25 89.4 0.0 3.9 3 1 0 4 4 4 4 Lipid-A-disaccharide synthetase NARP1 PF12569.8 RLN43938.1 - 4.7e-19 68.7 0.1 5.7e-19 68.4 0.1 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 DUF3323 PF11796.8 RLN43938.1 - 0.029 14.2 0.7 0.033 14.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) Solute_trans_a PF03619.16 RLN43939.1 - 9.8e-85 284.3 16.5 1.2e-84 284.0 16.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha MFMR_assoc PF16596.5 RLN43939.1 - 0.3 11.5 7.6 0.51 10.8 7.6 1.3 1 0 0 1 1 1 0 Disordered region downstream of MFMR CDC45 PF02724.14 RLN43939.1 - 0.82 7.9 11.0 1.1 7.4 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1373 PF07117.11 RLN43939.1 - 7.4 6.5 8.4 12 5.8 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) PDZ_6 PF17820.1 RLN43940.1 - 1.2e-06 28.2 0.0 0.014 15.2 0.0 3.5 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 RLN43940.1 - 7.1e-06 26.3 0.0 7.4 7.0 0.0 4.6 5 0 0 5 5 5 3 PDZ domain SprA-related PF12118.8 RLN43940.1 - 6.7 5.8 20.4 0.069 12.3 12.1 1.7 2 0 0 2 2 2 0 SprA-related family Hist_deacetyl PF00850.19 RLN43950.1 - 9.2e-22 77.9 0.8 1.7e-21 77.0 0.0 1.9 2 0 0 2 2 2 1 Histone deacetylase domain PTR2 PF00854.21 RLN43951.1 - 7.7e-58 196.2 9.5 1.2e-57 195.5 9.5 1.3 1 0 0 1 1 1 1 POT family Chordopox_A13L PF05961.11 RLN43951.1 - 0.082 13.2 1.7 0.31 11.3 0.0 2.8 2 0 0 2 2 2 0 Chordopoxvirus A13L protein DUF2157 PF09925.9 RLN43951.1 - 0.78 9.5 9.5 1.9 8.3 3.5 3.7 1 1 2 3 3 3 0 Predicted membrane protein (DUF2157) LpxC PF03331.13 RLN43952.1 - 3.7e-90 302.1 0.0 4.2e-90 301.9 0.0 1.0 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase DUF4403 PF14356.6 RLN43952.1 - 0.00034 19.4 0.0 0.0005 18.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4403) FYVE PF01363.21 RLN43953.1 - 4.1e-11 42.9 8.0 1.1e-10 41.5 8.0 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN43953.1 - 0.00076 19.7 4.2 0.0026 18.0 4.2 1.9 1 0 0 1 1 1 1 FYVE-type zinc finger NOB1_Zn_bind PF08772.11 RLN43953.1 - 0.19 11.9 7.2 0.48 10.6 7.2 1.6 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-RING_5 PF14634.6 RLN43953.1 - 0.52 10.3 9.9 1.4 9.0 9.9 1.8 1 0 0 1 1 1 0 zinc-RING finger domain SMN PF06003.12 RLN43953.1 - 2.1 7.5 6.3 5.8 6.1 6.3 1.7 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) zf-C3HC4_2 PF13923.6 RLN43953.1 - 4.6 7.2 10.2 1.6 8.7 5.1 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ABC2_membrane PF01061.24 RLN43954.1 - 2.1e-40 138.4 70.3 3.4e-29 101.8 33.2 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN43954.1 - 1.7e-15 57.7 0.0 2.5e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter PDR_CDR PF06422.12 RLN43954.1 - 1.8e-09 37.3 1.1 8.2e-07 28.8 0.0 3.3 2 0 0 2 2 2 1 CDR ABC transporter AAA_21 PF13304.6 RLN43954.1 - 7.6e-06 25.9 0.1 0.03 14.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 RLN43954.1 - 9.1e-05 21.7 18.3 9.1e-05 21.7 18.3 2.9 2 1 1 3 3 3 2 ABC-2 family transporter protein PDR_assoc PF08370.11 RLN43954.1 - 0.0018 17.9 13.1 0.0048 16.6 0.0 4.3 3 0 0 3 3 3 2 Plant PDR ABC transporter associated AAA_29 PF13555.6 RLN43954.1 - 0.0035 17.1 0.9 0.0077 15.9 0.9 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN43954.1 - 0.005 16.8 0.3 0.01 15.7 0.3 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 RLN43954.1 - 0.0083 15.7 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 RLN43954.1 - 0.079 13.5 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 RLN43954.1 - 0.17 11.3 0.1 1.5 8.2 0.1 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 RLN43954.1 - 0.23 11.2 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain PRP38 PF03371.15 RLN43955.1 - 2.7e-56 190.2 0.0 3.2e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 PRP38 family HPP PF04982.13 RLN43955.1 - 0.023 14.8 0.2 0.035 14.3 0.2 1.3 1 0 0 1 1 1 0 HPP family B12D PF06522.11 RLN43956.1 - 8.4e-14 51.1 0.0 9.5e-14 51.0 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit F-box PF00646.33 RLN43956.1 - 0.032 14.1 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 F-box domain BCAS2 PF05700.11 RLN43957.1 - 2.8e-26 92.5 11.1 3.3e-26 92.3 11.1 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Mt_ATP-synt_D PF05873.12 RLN43957.1 - 0.11 12.4 3.7 0.067 13.0 1.3 1.7 1 1 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) SNARE PF05739.19 RLN43957.1 - 0.47 10.5 4.9 1.2 9.1 0.1 2.8 2 1 1 3 3 3 0 SNARE domain Cellulase PF00150.18 RLN43958.1 - 5.9e-29 101.4 0.2 9.5e-29 100.7 0.2 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Peptidase_M13 PF01431.21 RLN43959.1 - 5.4e-63 212.3 0.7 6.2e-63 212.1 0.7 1.0 1 0 0 1 1 1 1 Peptidase family M13 DUF4684 PF15736.5 RLN43959.1 - 0.11 11.2 0.1 0.14 10.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) PIP5K PF01504.18 RLN43997.1 - 7.9e-66 222.1 0.0 1e-65 221.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_2 PF00002.24 RLN43997.1 - 0.0012 18.2 1.9 0.0022 17.3 1.9 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.17 RLN43997.1 - 0.0027 16.8 9.1 0.006 15.7 9.1 1.5 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region 7TM_GPCR_Srsx PF10320.9 RLN43997.1 - 0.0047 16.3 2.5 0.005 16.3 1.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx CAP_N PF01213.19 RLN43997.1 - 7 6.0 5.5 11 5.4 5.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal EF-hand_6 PF13405.6 RLN43998.1 - 6.7e-11 41.2 0.0 0.065 13.2 0.0 6.5 7 0 0 7 7 7 2 EF-hand domain EF-hand_1 PF00036.32 RLN43998.1 - 3.8e-08 32.3 0.0 0.66 9.7 0.0 5.6 6 0 0 6 6 6 2 EF hand EF-hand_7 PF13499.6 RLN43998.1 - 7.7e-08 32.7 0.0 2 8.9 0.0 5.3 5 1 0 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 RLN43998.1 - 0.00046 19.6 0.5 0.61 9.7 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 RLN43998.1 - 0.021 14.7 0.0 29 4.6 0.0 4.2 4 0 0 4 4 4 0 EF-hand domain pair PriC PF07445.12 RLN43999.1 - 0.0024 17.8 0.7 0.0028 17.6 0.7 1.1 1 0 0 1 1 1 1 Primosomal replication protein priC TMF_TATA_bd PF12325.8 RLN43999.1 - 0.021 15.1 0.8 0.033 14.4 0.8 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Wx5_PLAF3D7 PF09688.10 RLN43999.1 - 0.078 13.0 0.7 0.11 12.5 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (Wx5_PLAF3D7) DUF4763 PF15960.5 RLN43999.1 - 0.15 11.4 2.6 0.12 11.6 1.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) PTEN_C2 PF10409.9 RLN44000.1 - 1.5e-07 31.2 0.0 2.2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Aldo_ket_red PF00248.21 RLN44003.1 - 1.5e-47 162.2 0.0 2.1e-45 155.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family BCDHK_Adom3 PF10436.9 RLN44004.1 - 6.5e-14 52.1 0.2 5.4e-10 39.3 0.0 2.3 1 1 1 2 2 2 2 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 RLN44004.1 - 5.3e-11 43.0 0.0 1.8e-10 41.3 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 RLN44004.1 - 0.038 13.8 0.0 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 PF10436.9 RLN44005.1 - 1.8e-13 50.6 0.1 1.3e-08 34.9 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 RLN44005.1 - 2.4e-07 31.2 0.0 4.1e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RTP1_C1 PF10363.9 RLN44006.1 - 1.1e-26 93.1 2.7 2.5e-25 88.8 0.1 3.5 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 SNARE PF05739.19 RLN44006.1 - 3.9e-15 55.6 0.1 1e-14 54.3 0.1 1.8 1 0 0 1 1 1 1 SNARE domain RTP1_C2 PF10304.9 RLN44006.1 - 6.4e-06 25.7 0.9 6.4e-06 25.7 0.9 2.1 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 2 Syntaxin PF00804.25 RLN44006.1 - 0.011 15.4 0.2 0.011 15.4 0.2 3.4 4 0 0 4 4 4 0 Syntaxin DUF2951 PF11166.8 RLN44006.1 - 0.063 13.5 1.3 0.29 11.4 1.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) HEAT_PBS PF03130.16 RLN44006.1 - 0.21 12.4 3.8 0.62 10.9 0.8 3.7 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat HEAT_2 PF13646.6 RLN44006.1 - 0.26 11.7 6.1 0.15 12.4 0.4 3.6 3 0 0 3 3 3 0 HEAT repeats PHM7_cyt PF14703.6 RLN44006.1 - 0.43 10.8 2.9 47 4.1 0.2 3.7 2 1 2 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter MCPsignal PF00015.21 RLN44006.1 - 2.4 8.0 8.0 0.086 12.7 1.1 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain HEAT PF02985.22 RLN44006.1 - 3.2 8.2 5.1 25 5.5 0.1 4.6 4 0 0 4 4 4 0 HEAT repeat Transp_cyt_pur PF02133.15 RLN44008.1 - 9.5e-40 136.7 40.1 1.2e-39 136.4 40.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Phage_Coat_Gp8 PF05371.12 RLN44008.1 - 1.4 8.7 9.2 3.8 7.3 0.1 3.4 2 1 1 3 3 3 0 Phage major coat protein, Gp8 Transp_cyt_pur PF02133.15 RLN44009.1 - 9.6e-40 136.7 33.2 1.2e-39 136.3 33.2 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3712 PF12505.8 RLN44010.1 - 5.4e-36 123.6 1.3 1.1e-14 54.8 0.0 4.1 4 0 0 4 4 4 3 Protein of unknown function (DUF3712) LEA_2 PF03168.13 RLN44010.1 - 5.9e-05 23.5 0.0 3.4 8.3 0.0 4.5 6 0 0 6 6 6 2 Late embryogenesis abundant protein Glucan_synthase PF02364.15 RLN44011.1 - 2.3e-145 485.9 6.2 6.9e-127 424.8 2.2 2.5 1 1 1 2 2 2 2 1,3-beta-glucan synthase component PhoU_div PF01865.16 RLN44011.1 - 0.19 11.1 0.9 0.36 10.1 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF47 Ion_trans PF00520.31 RLN44013.1 - 9.6e-183 604.6 44.2 1.8e-49 168.2 0.1 4.3 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 RLN44013.1 - 1.2e-13 50.6 61.7 2.6e-07 29.7 2.4 10.5 8 3 3 11 11 11 7 Polycystin cation channel GPHH PF16905.5 RLN44013.1 - 7.5e-09 35.2 0.0 2.3e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Metallophos_C PF14008.6 RLN44013.1 - 0.049 14.5 0.0 0.1 13.4 0.0 1.6 1 0 0 1 1 1 0 Iron/zinc purple acid phosphatase-like protein C TPR_19 PF14559.6 RLN44014.1 - 3.8e-06 27.3 4.7 0.026 15.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN44014.1 - 0.00021 21.9 4.5 0.0018 18.9 2.9 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN44014.1 - 0.0012 19.0 0.7 0.13 12.7 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN44014.1 - 0.0031 17.2 0.0 0.0061 16.2 0.0 1.5 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 RLN44014.1 - 0.0061 16.6 1.5 8.8 6.7 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN44014.1 - 0.047 14.5 5.8 0.075 13.9 1.2 3.3 2 2 1 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.10 RLN44014.1 - 0.077 12.0 0.9 0.17 10.9 0.9 1.5 1 1 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Myb_DNA-binding PF00249.31 RLN44015.1 - 5.3e-13 48.9 1.0 8.1e-13 48.4 0.6 1.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN44015.1 - 0.095 13.0 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN44015.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Myb DNA-binding like Vfa1 PF08432.10 RLN44016.1 - 0.059 13.7 6.6 0.076 13.3 6.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2457 PF10446.9 RLN44016.1 - 0.18 10.9 20.9 0.21 10.7 20.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BSP_II PF05432.11 RLN44016.1 - 1.1 8.9 20.1 1.3 8.7 20.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SDA1 PF05285.12 RLN44016.1 - 1.2 8.5 18.4 1.7 8.0 18.4 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 RLN44016.1 - 7.6 4.5 23.0 8.7 4.3 23.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Rio2_N PF09202.11 RLN44017.1 - 1e-35 121.8 0.7 1.1e-34 118.5 0.2 2.4 3 0 0 3 3 3 1 Rio2, N-terminal RIO1 PF01163.22 RLN44017.1 - 3.1e-33 115.0 0.0 1.3e-32 112.9 0.0 1.9 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 RLN44017.1 - 7.4e-05 22.8 0.1 0.0011 18.9 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 RLN44017.1 - 0.0042 16.5 0.3 2.4 7.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Phage_TAC_2 PF06894.11 RLN44017.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G AA_permease_2 PF13520.6 RLN44019.1 - 3.3e-23 82.2 28.6 4.3e-23 81.8 28.6 1.2 1 0 0 1 1 1 1 Amino acid permease DUF1418 PF07214.12 RLN44019.1 - 2.4 8.1 5.9 0.27 11.1 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) Peptidase_C14 PF00656.22 RLN44022.1 - 0.03 14.3 0.0 0.054 13.4 0.0 1.7 1 1 0 1 1 1 0 Caspase domain Ank_4 PF13637.6 RLN44023.1 - 2.7e-30 104.4 5.5 2.2e-09 37.6 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN44023.1 - 2.1e-25 89.1 1.1 1.4e-15 57.7 0.7 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN44023.1 - 1.4e-20 71.2 0.0 0.00017 21.7 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 RLN44023.1 - 1.6e-20 72.9 1.2 1.8e-09 37.7 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN44023.1 - 1.3e-19 69.7 1.8 9.6e-05 22.7 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat DEAD PF00270.29 RLN44024.1 - 1.3e-39 135.8 0.0 3e-39 134.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN44024.1 - 4.9e-24 84.8 0.0 2.7e-23 82.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 RLN44024.1 - 7.1e-21 74.2 0.0 1.5e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.6 RLN44024.1 - 0.021 15.1 2.4 0.094 13.0 0.0 3.2 3 1 0 3 3 3 0 AAA domain Asr PF06392.11 RLN44024.1 - 0.11 12.9 4.8 0.47 10.9 4.8 2.2 1 0 0 1 1 1 0 Acid shock protein repeat DUF572 PF04502.13 RLN44024.1 - 5.4 6.5 31.3 6.9 6.2 31.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Mannosyl_trans3 PF11051.8 RLN44036.1 - 4e-35 121.5 0.0 5.6e-22 78.4 0.0 2.1 2 0 0 2 2 2 2 Mannosyltransferase putative CagY_I PF14585.6 RLN44037.1 - 0.045 13.9 3.1 0.58 10.3 0.2 2.7 2 0 0 2 2 2 0 CagY type 1 repeat Spectrin_like PF18373.1 RLN44037.1 - 1.6 8.8 4.6 1.3 9.1 0.1 3.0 3 1 0 3 3 3 0 Spectrin like domain MCPVI PF02993.14 RLN44037.1 - 3.4 7.4 15.4 4.6 7.0 3.4 2.4 1 1 0 2 2 2 0 Minor capsid protein VI DUF883 PF05957.13 RLN44037.1 - 9 7.0 25.2 0.85 10.3 2.2 4.1 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) Cyclin PF08613.11 RLN44062.1 - 3.2e-16 60.1 0.4 4.6e-16 59.6 0.4 1.2 1 0 0 1 1 1 1 Cyclin p31comet PF06581.12 RLN44062.1 - 0.021 14.0 0.1 0.027 13.6 0.1 1.1 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding Cyclin_N PF00134.23 RLN44062.1 - 0.15 11.8 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Cyclin, N-terminal domain Pkinase PF00069.25 RLN44063.1 - 0.00055 19.4 0.0 0.00056 19.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN44063.1 - 0.014 14.7 0.0 0.015 14.6 0.0 1.0 1 0 0 1 1 1 0 Protein tyrosine kinase Methyltransf_31 PF13847.6 RLN44064.1 - 1e-09 38.4 0.0 6e-07 29.4 0.0 2.1 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 RLN44064.1 - 1.7e-09 38.2 0.0 5.4e-08 33.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN44064.1 - 1.7e-08 35.0 0.1 0.00011 22.8 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 RLN44064.1 - 1.2e-06 28.4 0.0 1.5e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN44064.1 - 2e-06 28.4 0.0 7.1e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN44064.1 - 0.037 13.3 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CheR PF01739.18 RLN44064.1 - 0.096 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain DREV PF05219.12 RLN44064.1 - 0.15 11.1 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_16 PF10294.9 RLN44079.1 - 1.3e-27 96.7 0.1 3.6e-26 91.9 0.1 2.0 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 RLN44079.1 - 0.0026 17.4 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain TPR_12 PF13424.6 RLN44080.1 - 5.4e-15 55.4 8.6 1.8e-09 37.8 1.5 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN44080.1 - 2.3e-13 49.5 4.6 4.3e-06 26.4 0.7 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN44080.1 - 1e-12 47.3 6.2 2.4e-05 23.9 0.3 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN44080.1 - 1e-11 44.0 6.8 0.00014 21.7 0.2 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN44080.1 - 5.4e-08 32.3 4.9 0.0015 18.4 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN44080.1 - 2.3e-07 30.5 1.6 0.0046 17.1 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF5113 PF17140.4 RLN44080.1 - 0.0069 16.2 0.5 29 4.4 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5113) TPR_MalT PF17874.1 RLN44080.1 - 0.0093 15.4 1.6 0.0093 15.4 1.6 1.9 1 1 0 2 2 2 1 MalT-like TPR region AlgF PF11182.8 RLN44080.1 - 0.015 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF TPR_19 PF14559.6 RLN44080.1 - 0.018 15.5 3.9 0.31 11.6 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN44080.1 - 0.024 15.5 3.8 36 5.5 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 RLN44080.1 - 0.036 13.7 0.3 17 5.2 0.0 3.7 4 1 0 4 4 4 0 TPR repeat TPR_15 PF13429.6 RLN44080.1 - 0.057 12.6 1.1 0.78 8.9 0.1 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN44080.1 - 0.14 12.9 0.9 8.3 7.1 0.2 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 RLN44080.1 - 0.34 11.4 4.7 0.91 10.1 0.1 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN44080.1 - 0.58 10.4 5.6 4.7 7.5 0.6 3.4 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Mon1 PF03164.14 RLN44081.1 - 7.1e-55 186.7 0.0 1.2e-53 182.7 0.0 2.1 1 1 0 1 1 1 1 Trafficking protein Mon1 Glycos_transf_1 PF00534.20 RLN44081.1 - 7.2e-23 81.0 0.0 1.2e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RLN44081.1 - 7.3e-18 65.3 0.0 1.8e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 RLN44081.1 - 7.8e-06 26.2 0.0 2.8e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 Ank_2 PF12796.7 RLN44082.1 - 3.4e-35 120.5 2.3 8.8e-15 55.1 0.0 5.4 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN44082.1 - 4.2e-29 97.4 10.3 1e-06 28.5 0.0 9.1 8 1 1 9 9 9 5 Ankyrin repeat Ank_4 PF13637.6 RLN44082.1 - 5e-29 100.3 12.1 8.2e-10 39.0 0.1 7.7 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN44082.1 - 1.8e-27 95.0 11.9 3.9e-08 33.4 0.2 6.4 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 RLN44082.1 - 2.8e-24 84.5 17.3 4.4e-07 30.1 0.0 8.1 8 0 0 8 8 8 4 Ankyrin repeat HA2 PF04408.23 RLN44100.1 - 2.2e-21 76.2 0.1 4e-21 75.3 0.1 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RLN44100.1 - 3.6e-19 68.9 0.0 6.3e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Rieske_2 PF13806.6 RLN44101.1 - 2.4e-19 69.2 0.0 5.2e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NIR_SIR PF01077.22 RLN44101.1 - 4.7e-15 55.4 0.0 7.2e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 RLN44101.1 - 3.9e-08 33.0 0.0 6.7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.26 RLN44101.1 - 5.2e-07 29.5 0.0 9.4e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Esterase PF00756.20 RLN44113.1 - 0.0077 15.9 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase TMEM247 PF15444.6 RLN44116.1 - 0.77 9.8 8.9 1.6 8.8 8.8 1.6 1 1 0 1 1 1 0 Transmembrane protein 247 CDC45 PF02724.14 RLN44116.1 - 3.8 5.7 14.8 4.6 5.4 14.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DDE_Tnp_1_6 PF13751.6 RLN44116.1 - 7.6 6.8 9.8 1.1 9.5 0.3 2.2 2 0 0 2 2 2 0 Transposase DDE domain Ank_2 PF12796.7 RLN44121.1 - 2.6e-24 85.6 1.4 5.3e-07 30.1 0.1 5.1 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN44121.1 - 9.5e-19 67.5 8.7 3.4e-06 27.5 0.1 6.2 5 3 3 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN44121.1 - 3.2e-14 52.8 7.3 0.58 10.5 0.0 8.5 5 2 5 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN44121.1 - 4.7e-13 48.0 3.2 1.6 9.5 0.0 9.5 9 2 2 11 11 11 3 Ankyrin repeat Ank PF00023.30 RLN44121.1 - 0.055 13.9 0.2 80 3.9 0.0 4.7 3 1 1 4 4 4 0 Ankyrin repeat DUF4287 PF14117.6 RLN44121.1 - 0.41 10.8 7.9 7.5 6.8 0.4 4.3 4 1 1 5 5 5 0 Domain of unknown function (DUF4287) Ank_2 PF12796.7 RLN44122.1 - 6.4e-07 29.9 0.0 0.0034 17.9 0.0 2.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN44122.1 - 2.2e-05 24.5 0.2 46 5.1 0.0 5.9 6 1 1 7 7 7 0 Ankyrin repeat Ank_4 PF13637.6 RLN44122.1 - 5.2e-05 23.7 1.7 0.0078 16.8 0.0 4.0 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN44122.1 - 0.036 14.4 0.3 39 4.7 0.0 4.6 1 1 4 5 5 5 0 Ankyrin repeats (many copies) DUF2423 PF10338.9 RLN44125.1 - 1.3 9.3 5.4 1.8 8.8 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2423) Presenilin PF01080.17 RLN44125.1 - 9.2 4.9 4.7 10 4.8 4.7 1.0 1 0 0 1 1 1 0 Presenilin TPR_2 PF07719.17 RLN44131.1 - 1.7e-24 83.9 28.0 0.022 14.8 0.0 12.4 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_1 PF00515.28 RLN44131.1 - 1.6e-20 72.0 40.3 0.0005 19.8 0.0 12.2 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_6 PF13174.6 RLN44131.1 - 1.9e-20 72.0 2.6 0.0063 17.1 0.1 11.3 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_19 PF14559.6 RLN44131.1 - 1.9e-18 66.7 15.3 0.0033 17.9 0.1 8.6 4 3 1 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 RLN44131.1 - 2.6e-18 66.1 16.5 0.00017 21.8 0.0 8.7 6 3 2 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 RLN44131.1 - 3.8e-15 54.7 15.6 0.019 15.0 0.0 9.2 10 0 0 10 10 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 RLN44131.1 - 8.4e-14 51.1 6.2 0.15 13.0 0.0 9.2 8 3 3 11 11 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN44131.1 - 6.4e-13 48.7 20.7 0.00096 19.3 1.0 7.2 6 1 1 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 zf-C2HC_2 PF13913.6 RLN44131.1 - 2e-12 46.7 20.5 6.9e-09 35.4 0.3 4.1 4 0 0 4 4 4 2 zinc-finger of a C2HC-type TPR_11 PF13414.6 RLN44131.1 - 6e-11 41.8 11.4 0.07 12.8 0.0 8.1 7 1 1 8 8 8 3 TPR repeat TPR_8 PF13181.6 RLN44131.1 - 2.5e-09 36.6 28.2 0.2 11.9 0.0 11.3 13 0 0 13 13 11 3 Tetratricopeptide repeat WW PF00397.26 RLN44131.1 - 3.8e-09 36.5 3.8 7.8e-09 35.5 3.8 1.5 1 0 0 1 1 1 1 WW domain TPR_16 PF13432.6 RLN44131.1 - 5.3e-09 36.6 9.3 0.34 11.6 0.0 8.3 4 4 5 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.6 RLN44131.1 - 2e-08 34.3 0.0 0.11 12.6 0.0 4.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 RLN44131.1 - 0.00014 22.0 9.5 0.26 11.7 0.0 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 RLN44131.1 - 0.00097 18.6 12.2 0.3 10.4 0.0 5.5 5 1 1 6 6 5 2 MalT-like TPR region Fis1_TPR_C PF14853.6 RLN44131.1 - 0.0034 17.4 2.0 6.2 7.0 0.0 5.8 5 1 1 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat DUF3808 PF10300.9 RLN44131.1 - 0.0061 15.3 1.6 0.15 10.8 0.0 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF3808) DUF2225 PF09986.9 RLN44131.1 - 0.0069 16.1 0.6 0.0069 16.1 0.6 4.3 4 1 0 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) DUF4810 PF16068.5 RLN44131.1 - 0.0074 16.8 0.5 6.2 7.4 0.0 5.6 6 0 0 6 6 6 1 Domain of unknown function (DUF4810) SRP_TPR_like PF17004.5 RLN44131.1 - 0.7 9.9 12.4 4.1 7.4 0.8 4.8 3 2 2 5 5 5 0 Putative TPR-like repeat Glyco_tran_28_C PF04101.16 RLN44131.1 - 4.5 7.2 7.3 0.41 10.6 0.1 2.7 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain Ank_2 PF12796.7 RLN44132.1 - 1.2e-31 109.2 6.9 9.5e-09 35.7 0.0 3.6 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN44132.1 - 9.4e-20 70.4 7.8 0.011 16.0 0.0 7.0 3 1 5 8 8 8 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN44132.1 - 4.7e-18 65.3 4.7 2.6e-07 31.1 0.2 5.1 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN44132.1 - 4e-12 45.2 1.1 0.34 11.6 0.0 6.9 5 2 2 7 7 7 2 Ankyrin repeat Ank PF00023.30 RLN44132.1 - 1.5e-06 28.4 0.2 5.5 7.6 0.0 6.0 1 1 3 4 4 4 1 Ankyrin repeat DUF5049 PF16468.5 RLN44132.1 - 0.0001 22.1 0.0 0.57 10.1 0.0 4.6 5 0 0 5 5 5 1 Domain of unknown function (DUF5049) HA PF03457.14 RLN44132.1 - 0.014 15.7 0.0 2.4 8.6 0.0 3.3 1 1 0 1 1 1 0 Helicase associated domain JAB PF01398.21 RLN44132.1 - 0.025 14.6 0.2 4.2 7.4 0.1 3.1 2 1 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4411 PF14367.6 RLN44132.1 - 0.08 12.8 0.1 18 5.2 0.0 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4411) DUF1843 PF08898.10 RLN44132.1 - 0.14 12.6 0.4 11 6.7 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DUF1987 PF09345.10 RLN44132.1 - 0.16 11.6 2.3 38 4.0 0.1 3.9 2 1 1 4 4 4 0 Domain of unknown function (DUF1987) TPR_19 PF14559.6 RLN44133.1 - 6.6e-46 154.7 53.3 2.5e-07 31.1 1.1 15.6 13 3 3 16 16 15 10 Tetratricopeptide repeat TPR_2 PF07719.17 RLN44133.1 - 2.4e-32 108.4 61.5 0.0052 16.8 0.0 21.6 24 0 0 24 24 23 7 Tetratricopeptide repeat TPR_14 PF13428.6 RLN44133.1 - 2.8e-32 108.6 61.0 0.0023 18.6 0.0 20.1 13 6 8 21 21 20 9 Tetratricopeptide repeat TPR_16 PF13432.6 RLN44133.1 - 4.8e-28 97.5 56.1 0.0014 19.2 0.1 14.0 11 3 3 15 15 15 9 Tetratricopeptide repeat TPR_1 PF00515.28 RLN44133.1 - 1e-24 85.3 43.6 0.0022 17.7 0.1 17.9 21 0 0 21 21 18 4 Tetratricopeptide repeat TPR_8 PF13181.6 RLN44133.1 - 2.6e-23 80.2 29.8 0.008 16.3 0.1 16.3 17 0 0 17 17 15 4 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN44133.1 - 5e-20 71.5 38.9 0.0028 17.9 0.3 10.4 8 3 2 10 10 9 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 RLN44133.1 - 4.7e-16 58.8 52.4 0.0051 17.1 0.2 14.8 10 5 3 13 13 13 6 Tetratricopeptide repeat TPR_7 PF13176.6 RLN44133.1 - 2.9e-11 42.6 43.6 0.017 15.1 0.0 16.2 18 1 1 19 19 18 3 Tetratricopeptide repeat TPR_9 PF13371.6 RLN44133.1 - 3.6e-11 43.0 42.6 5.5e-05 23.2 0.1 9.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 RLN44133.1 - 2.6e-10 39.8 25.5 0.00019 21.1 0.1 10.3 12 1 1 13 13 11 3 TPR repeat TPR_6 PF13174.6 RLN44133.1 - 3.1e-10 40.0 46.0 0.43 11.3 0.2 17.1 20 0 0 20 20 17 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN44133.1 - 2.3e-07 30.7 30.1 3 8.4 0.3 13.3 15 1 0 15 15 11 1 Tetratricopeptide repeat RPN7 PF10602.9 RLN44133.1 - 0.00011 21.9 2.0 4.4 7.0 0.1 5.7 5 1 2 7 7 7 1 26S proteasome subunit RPN7 PknG_TPR PF16918.5 RLN44133.1 - 0.00041 19.2 7.2 0.13 11.0 0.0 5.0 4 1 0 4 4 4 1 Protein kinase G tetratricopeptide repeat Coatomer_E PF04733.14 RLN44133.1 - 0.00048 19.6 5.9 0.33 10.3 0.1 4.5 4 1 0 4 4 4 2 Coatomer epsilon subunit LppC PF04348.13 RLN44133.1 - 0.00077 18.4 8.4 0.0032 16.3 0.4 3.0 3 0 0 3 3 3 2 LppC putative lipoprotein ChAPs PF09295.10 RLN44133.1 - 0.0012 17.9 4.9 0.084 11.9 0.1 4.4 4 1 0 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 RLN44133.1 - 0.0073 16.6 22.8 0.1 13.0 0.8 6.9 6 0 0 6 6 5 2 Tetratricopeptide repeat YfiO PF13525.6 RLN44133.1 - 0.0078 16.0 2.9 3.4 7.3 0.0 4.8 5 0 0 5 5 4 1 Outer membrane lipoprotein MIT PF04212.18 RLN44133.1 - 0.027 14.5 8.7 29 4.8 0.1 6.8 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain DUF627 PF04781.12 RLN44133.1 - 0.031 14.3 2.8 6.3 6.9 0.0 4.2 5 0 0 5 5 2 0 Protein of unknown function (DUF627) SHNi-TPR PF10516.9 RLN44133.1 - 0.081 12.4 2.2 6.7 6.3 0.1 4.0 3 0 0 3 3 3 0 SHNi-TPR Alkyl_sulf_dimr PF14863.6 RLN44133.1 - 0.083 13.3 15.5 12 6.4 0.4 6.9 6 1 1 7 7 7 0 Alkyl sulfatase dimerisation TPR_4 PF07721.14 RLN44133.1 - 0.094 13.4 48.7 1.1 10.0 1.7 12.2 13 0 0 13 13 10 0 Tetratricopeptide repeat ImpA_N PF06812.12 RLN44133.1 - 0.15 12.2 2.6 5.3 7.2 0.0 4.3 4 0 0 4 4 4 0 ImpA, N-terminal, type VI secretion system TPR_21 PF09976.9 RLN44133.1 - 0.23 11.2 35.9 4.5 6.9 2.1 7.6 7 0 0 7 7 7 0 Tetratricopeptide repeat-like domain PPR PF01535.20 RLN44133.1 - 0.77 10.2 4.3 65 4.1 0.0 5.8 7 0 0 7 7 3 0 PPR repeat HrpB1_HrpK PF09613.10 RLN44133.1 - 2 8.1 17.7 2.9 7.6 0.0 6.4 8 1 1 9 9 8 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_10 PF13374.6 RLN44133.1 - 2.4 8.2 26.1 8.2 6.4 0.1 10.0 11 0 0 11 11 10 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN44133.1 - 6.3 7.0 21.6 5.1 7.2 0.5 7.7 9 1 0 9 9 7 0 Fis1 C-terminal tetratricopeptide repeat Pkinase PF00069.25 RLN44134.1 - 8.1e-70 235.2 0.0 1.1e-69 234.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN44134.1 - 1e-39 136.4 0.0 1.5e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 RLN44134.1 - 8e-38 128.5 0.0 2.8e-19 69.1 0.0 2.5 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 RLN44134.1 - 2.3e-07 30.4 0.0 6.5e-07 28.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 RLN44134.1 - 0.0086 16.0 0.1 0.02 14.8 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ank_4 PF13637.6 RLN44135.1 - 6.7e-25 87.1 18.3 7.2e-08 32.8 0.1 4.2 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN44135.1 - 6.8e-24 84.3 17.4 5.6e-08 33.3 0.5 3.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN44135.1 - 1.8e-16 60.0 11.6 2.9e-05 24.3 0.1 6.5 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN44135.1 - 2.4e-12 45.9 6.2 1.5 9.6 0.0 6.9 6 1 1 7 7 7 4 Ankyrin repeat HA PF03457.14 RLN44135.1 - 0.00033 20.9 0.0 0.28 11.5 0.1 3.9 2 2 1 3 3 3 1 Helicase associated domain Ank PF00023.30 RLN44135.1 - 0.0026 18.1 3.3 45 4.7 0.3 5.6 1 1 1 2 2 2 0 Ankyrin repeat DUF4411 PF14367.6 RLN44135.1 - 0.16 11.9 2.2 7.6 6.4 0.2 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4411) IFS PF16718.5 RLN44181.1 - 0.031 14.4 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 Immunity factor for SPN Peroxidase_2 PF01328.17 RLN44240.1 - 2.1e-56 191.4 0.0 2.5e-56 191.2 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Peroxidase_2 PF01328.17 RLN44241.1 - 9.8e-50 169.7 0.0 1.4e-49 169.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Voltage_CLC PF00654.20 RLN44242.1 - 1.1e-11 44.6 4.3 1.5e-11 44.2 4.3 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel TRAM_LAG1_CLN8 PF03798.16 RLN44324.1 - 0.0011 18.7 9.8 0.0022 17.8 9.6 1.6 1 1 0 1 1 1 1 TLC domain Peptidase_M28 PF04389.17 RLN44326.1 - 7.2e-17 61.7 0.0 1.2e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 RLN44326.1 - 3.3e-11 43.1 0.1 2.4e-10 40.3 0.0 2.3 2 0 0 2 2 2 1 PA domain TFR_dimer PF04253.15 RLN44327.1 - 3.8e-28 98.0 0.0 7.5e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 RLN44327.1 - 6.2e-18 65.2 0.0 1.2e-17 64.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 RLN44327.1 - 2.8e-05 23.9 0.1 6.1e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WXG100 PF06013.12 RLN44327.1 - 0.0063 16.7 0.2 1 9.6 0.1 3.2 2 1 1 3 3 3 1 Proteins of 100 residues with WXG SUKH-4 PF14435.6 RLN44327.1 - 0.051 13.6 1.5 0.16 12.0 0.9 2.1 2 0 0 2 2 2 0 SUKH-4 immunity protein CAS_C PF12026.8 RLN44327.1 - 0.16 12.0 0.1 0.27 11.3 0.1 1.3 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain Mannosyl_trans3 PF11051.8 RLN44352.1 - 1.5e-35 122.9 0.1 1.4e-33 116.4 0.1 2.3 1 1 0 1 1 1 1 Mannosyltransferase putative Fis1_TPR_C PF14853.6 RLN44362.1 - 2e-12 47.0 0.1 3.7e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TRAM_LAG1_CLN8 PF03798.16 RLN44362.1 - 2.3e-09 37.3 5.5 3.1e-09 36.8 5.5 1.2 1 0 0 1 1 1 1 TLC domain TPR_2 PF07719.17 RLN44362.1 - 0.0029 17.6 0.0 0.0088 16.1 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN44362.1 - 0.11 12.8 0.4 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-CCCH PF00642.24 RLN44363.1 - 1.1e-18 66.7 16.8 3.7e-11 42.7 5.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RLN44363.1 - 1.1e-13 50.7 16.7 7.1e-07 29.1 6.4 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 RLN44363.1 - 2.1e-13 49.7 13.4 4.6e-08 32.7 3.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 RLN44363.1 - 6.4e-05 23.3 11.0 0.0081 16.6 2.3 2.6 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 RLN44363.1 - 0.0004 21.0 10.5 0.044 14.5 1.1 2.3 1 1 1 2 2 2 2 Torus domain zf-CCHH PF10283.9 RLN44363.1 - 4.7 7.3 10.3 9.2 6.4 1.6 2.9 2 0 0 2 2 2 0 PBZ domain HBS1_N PF08938.10 RLN44364.1 - 0.13 12.5 1.2 0.24 11.7 1.1 1.5 1 1 0 1 1 1 0 HBS1 N-terminus DCP2 PF05026.13 RLN44365.1 - 6.2e-27 93.8 3.8 1.1e-26 93.0 3.8 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 RLN44365.1 - 4e-15 56.0 0.0 6.8e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain YIF1 PF03878.15 RLN44366.1 - 0.0015 18.1 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 YIF1 DUF1115 PF06544.12 RLN44367.1 - 5.7e-41 140.0 0.3 7.3e-41 139.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) PRP3 PF08572.10 RLN44368.1 - 6.8e-59 199.3 11.1 1.1e-58 198.6 11.1 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) HR1 PF02185.16 RLN44369.1 - 2.5 8.3 16.6 0.15 12.2 6.6 2.8 2 1 0 2 2 2 0 Hr1 repeat HR1 PF02185.16 RLN44370.1 - 0.37 10.9 6.4 1.6 8.9 6.4 2.2 1 1 0 1 1 1 0 Hr1 repeat Cu-oxidase_2 PF07731.14 RLN44443.1 - 3.3e-33 114.3 16.2 1.5e-28 99.3 4.1 4.5 4 2 0 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN44443.1 - 3.8e-32 110.8 2.0 1.1e-29 102.9 0.2 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 RLN44443.1 - 5.3e-27 94.9 0.0 2.2e-26 92.9 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 RLN44444.1 - 1.3e-37 128.6 3.8 2.7e-29 101.7 0.2 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN44444.1 - 2.3e-32 111.5 3.7 6.7e-31 106.8 0.2 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 RLN44444.1 - 1.3e-27 96.8 0.3 6.6e-27 94.6 0.0 2.3 3 0 0 3 3 3 1 Multicopper oxidase adh_short PF00106.25 RLN44445.1 - 6.5e-45 153.0 1.3 8.9e-45 152.5 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN44445.1 - 6.1e-30 104.5 1.1 8.5e-30 104.0 1.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN44445.1 - 5.8e-08 32.8 1.6 8.5e-08 32.3 1.6 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 RLN44445.1 - 4.3e-06 26.3 0.0 5.8e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 RLN44445.1 - 0.076 12.5 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 RLN44445.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.25 RLN44446.1 - 4e-44 150.4 0.2 5.3e-44 150.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN44446.1 - 1.2e-29 103.6 0.4 1.5e-29 103.2 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN44446.1 - 1.2e-06 28.5 0.2 1.7e-06 28.1 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 RLN44446.1 - 4.7e-05 23.4 2.2 7e-05 22.8 2.2 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Mce4_CUP1 PF11887.8 RLN44446.1 - 0.0023 17.4 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative ADH_zinc_N PF00107.26 RLN44446.1 - 0.0027 17.7 0.3 0.0065 16.4 0.3 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NmrA PF05368.13 RLN44446.1 - 0.0091 15.6 0.0 0.28 10.7 0.2 2.0 2 0 0 2 2 2 1 NmrA-like family DUF1776 PF08643.10 RLN44446.1 - 0.03 13.7 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 RLN44446.1 - 0.032 13.7 0.3 0.06 12.8 0.3 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 RLN44447.1 - 6.3e-42 143.2 0.1 7.9e-42 142.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN44447.1 - 1.2e-28 100.3 0.2 1.8e-28 99.7 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN44447.1 - 0.0018 18.2 0.3 0.0027 17.7 0.3 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 RLN44447.1 - 0.017 14.5 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Enterotoxin_HS1 PF08090.11 RLN44447.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Heat stable E.coli enterotoxin 1 Trypsin_2 PF13365.6 RLN44448.1 - 2e-14 54.7 0.4 4.5e-14 53.6 0.2 1.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain EF-hand_1 PF00036.32 RLN44449.1 - 1.3e-20 71.3 2.6 1.3e-06 27.5 0.1 3.8 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 RLN44449.1 - 1.2e-18 66.7 3.8 3.7e-12 45.9 0.5 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RLN44449.1 - 8.9e-18 62.6 1.6 4.3e-05 23.1 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 RLN44449.1 - 1.5e-17 63.8 11.0 6.5e-11 42.5 1.4 3.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN44449.1 - 2.3e-15 55.3 4.3 2e-05 23.9 0.2 4.1 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 RLN44449.1 - 1.3e-05 25.4 0.7 0.00099 19.4 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain Mlo PF03094.15 RLN44449.1 - 0.00072 18.1 7.4 0.1 10.9 0.5 2.2 1 1 1 2 2 2 2 Mlo family EF-hand_4 PF12763.7 RLN44449.1 - 0.0066 16.4 2.3 0.74 9.8 0.2 3.3 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand DUF996 PF06195.13 RLN44449.1 - 0.041 14.2 2.8 0.06 13.6 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF996) EF-hand_11 PF08976.11 RLN44449.1 - 0.058 14.3 0.2 4.8 8.1 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain DUF3349 PF11829.8 RLN44449.1 - 0.077 13.8 0.3 28 5.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) UPF0182 PF03699.13 RLN44449.1 - 2.4 6.2 3.8 3.5 5.6 3.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) OppC_N PF12911.7 RLN44449.1 - 5.1 7.1 7.0 57 3.8 0.1 4.3 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C Peptidase_C1 PF00112.23 RLN44450.1 - 4.7e-56 190.3 2.2 6.4e-56 189.9 2.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RLN44450.1 - 0.016 14.0 3.7 1.2 7.8 0.2 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Got1 PF04178.12 RLN44451.1 - 1.8e-21 76.7 14.2 2.3e-21 76.3 14.2 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family PTS_EIIC PF02378.18 RLN44451.1 - 0.0006 18.9 1.2 0.0011 18.1 1.2 1.3 1 0 0 1 1 1 1 Phosphotransferase system, EIIC PhaP_Bmeg PF09602.10 RLN44451.1 - 0.022 14.7 4.2 0.038 13.9 4.2 1.5 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) TSNAXIP1_N PF15739.5 RLN44451.1 - 0.022 15.1 4.4 0.053 13.9 4.4 1.6 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus TFIIE_alpha PF02002.17 RLN44451.1 - 0.077 12.9 0.5 0.14 12.1 0.5 1.4 1 0 0 1 1 1 0 TFIIE alpha subunit DUF1003 PF06210.11 RLN44451.1 - 1.1 9.4 0.0 1.1 9.4 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1003) Hydrolase_4 PF12146.8 RLN44452.1 - 7e-48 163.0 0.2 9.2e-48 162.6 0.2 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN44452.1 - 1.6e-07 31.2 0.1 3.7e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN44452.1 - 3.4e-05 23.4 0.1 0.0023 17.5 0.0 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 RLN44452.1 - 9.6e-05 23.1 0.4 9.6e-05 23.1 0.4 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 RLN44452.1 - 0.12 12.1 0.1 0.65 9.8 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Metallopep PF12044.8 RLN44453.1 - 1.5e-31 109.5 0.0 8.1e-31 107.1 0.0 1.8 1 1 0 1 1 1 1 Putative peptidase family HTH_33 PF13592.6 RLN44453.1 - 0.052 13.2 0.1 8.7 6.1 0.0 3.1 3 0 0 3 3 3 0 Winged helix-turn helix DUF5010_C PF18099.1 RLN44453.1 - 0.14 12.3 0.0 0.77 9.9 0.0 2.2 3 0 0 3 3 3 0 DUF5010 C-terminal domain Cu-oxidase_2 PF07731.14 RLN44454.1 - 5.8e-38 129.7 3.9 1.6e-29 102.4 0.1 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN44454.1 - 5.4e-34 116.8 2.4 1.3e-31 109.1 0.3 3.7 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 RLN44454.1 - 6.6e-24 84.8 0.0 2.5e-23 83.0 0.0 2.0 1 0 0 1 1 1 1 Multicopper oxidase ThiF PF00899.21 RLN44455.1 - 1.6e-25 89.9 0.0 3.3e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 ThiF family IQ PF00612.27 RLN44455.1 - 6.6e-08 31.7 63.7 0.094 12.6 4.4 8.3 8 0 0 8 8 8 7 IQ calmodulin-binding motif GLYCAM-1 PF05242.11 RLN44455.1 - 0.043 14.0 0.3 0.2 11.8 0.1 2.1 2 0 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) LRR_6 PF13516.6 RLN44456.1 - 1.3e-13 49.8 26.1 0.00054 19.8 0.2 7.6 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 RLN44456.1 - 3.8e-07 30.3 21.6 0.0044 17.4 0.4 5.2 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN44456.1 - 0.51 10.1 25.9 4.9 7.0 0.1 5.8 3 2 2 5 5 5 0 Leucine rich repeat LRR_1 PF00560.33 RLN44456.1 - 6.1 7.8 16.6 12 6.9 0.2 6.5 8 0 0 8 8 8 0 Leucine Rich Repeat Pex16 PF08610.10 RLN44457.1 - 5.1e-54 183.6 0.4 2.2e-31 109.2 0.0 2.1 1 1 1 2 2 2 2 Peroxisomal membrane protein (Pex16) DUF2530 PF10745.9 RLN44457.1 - 0.073 13.3 0.6 0.21 11.8 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) zf-H2C2_2 PF13465.6 RLN44458.1 - 2.7e-13 49.7 32.1 1.2e-06 28.7 2.2 5.2 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 RLN44458.1 - 2.8e-13 49.5 34.5 0.00042 20.6 2.0 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN44458.1 - 1.2e-11 44.4 30.3 0.0032 18.2 5.5 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RLN44458.1 - 0.00016 21.9 6.3 3.7 7.9 0.1 4.3 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 RLN44458.1 - 0.0064 16.8 9.6 0.71 10.2 1.5 3.1 1 1 2 3 3 3 3 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 RLN44458.1 - 0.019 15.0 24.6 0.12 12.4 3.5 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf_Hakai PF18408.1 RLN44458.1 - 0.13 12.0 0.3 0.13 12.0 0.3 2.8 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain zf_ZIC PF18366.1 RLN44458.1 - 0.29 11.3 9.6 1.3 9.2 0.2 3.4 2 1 1 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_aberr PF17017.5 RLN44458.1 - 0.35 11.0 10.2 5.7 7.1 0.1 3.6 1 1 3 4 4 4 0 Aberrant zinc-finger CHORD PF04968.12 RLN44458.1 - 0.97 10.2 16.8 2.9 8.7 0.4 4.0 2 2 2 4 4 4 0 CHORD zf-H2C2_5 PF13909.6 RLN44458.1 - 1.1 9.1 14.9 2 8.2 1.3 4.3 4 0 0 4 4 4 0 C2H2-type zinc-finger domain FKBP_C PF00254.28 RLN44459.1 - 7.1e-21 74.3 0.0 9.8e-21 73.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase V-set PF07686.17 RLN44459.1 - 0.078 13.2 0.0 3.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin V-set domain FKBP_N_2 PF18023.1 RLN44459.1 - 0.15 12.1 0.0 0.2 11.8 0.0 1.3 1 1 0 1 1 1 0 BDBT FKBP like N-terminal zf-C2H2 PF00096.26 RLN44461.1 - 1.9e-15 56.3 31.0 0.00041 20.7 3.2 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RLN44461.1 - 1.5e-12 47.3 25.3 4.4e-07 30.0 1.7 5.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 RLN44461.1 - 2.4e-12 46.6 27.0 0.012 16.4 1.7 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RLN44461.1 - 1.6e-06 28.0 21.6 0.0039 17.2 0.5 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RLN44461.1 - 0.0003 21.0 4.4 1.3 9.4 0.1 4.2 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 RLN44461.1 - 0.0075 16.0 14.4 1 9.2 0.2 4.5 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 RLN44461.1 - 0.0075 16.5 10.0 0.34 11.2 1.2 2.8 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf_Hakai PF18408.1 RLN44461.1 - 0.056 13.2 1.0 0.056 13.2 1.0 2.6 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain GAGA PF09237.11 RLN44461.1 - 0.33 10.8 4.5 0.4 10.5 2.0 2.3 2 0 0 2 2 2 0 GAGA factor zf_ZIC PF18366.1 RLN44461.1 - 0.43 10.7 8.0 11 6.2 0.2 3.5 2 1 1 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_aberr PF17017.5 RLN44461.1 - 2.6 8.1 6.9 4.7 7.3 0.5 3.0 1 1 2 3 3 3 0 Aberrant zinc-finger FOXP-CC PF16159.5 RLN44461.1 - 6.6 7.4 9.3 18 6.1 0.4 3.2 3 1 1 4 4 4 0 FOXP coiled-coil domain UCH PF00443.29 RLN44462.1 - 8.3e-31 107.4 0.0 1.9e-30 106.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN44462.1 - 1.5e-09 37.9 0.0 3.8e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PX PF00787.24 RLN44464.1 - 9.3e-06 25.6 0.3 1.8e-05 24.7 0.0 1.5 2 0 0 2 2 2 1 PX domain DUF1398 PF07166.11 RLN44464.1 - 0.041 13.9 0.1 0.052 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) DUF2491 PF10679.9 RLN44464.1 - 0.12 11.5 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) PX PF00787.24 RLN44465.1 - 4.3e-07 29.9 0.6 1e-06 28.7 0.6 1.5 1 0 0 1 1 1 1 PX domain FH2 PF02181.23 RLN44466.1 - 1.8e-36 126.1 0.3 1.7e-34 119.6 0.3 2.1 1 1 0 1 1 1 1 Formin Homology 2 Domain ABC1 PF03109.16 RLN44466.1 - 4.5e-32 110.7 0.0 1.1e-31 109.4 0.0 1.7 1 0 0 1 1 1 1 ABC1 family CCDC53 PF10152.9 RLN44466.1 - 0.00034 21.1 0.9 0.00073 20.0 0.0 2.1 2 0 0 2 2 2 1 Subunit CCDC53 of WASH complex INCENP_N PF12178.8 RLN44467.1 - 0.076 13.0 0.5 0.076 13.0 0.5 2.0 2 0 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal HTH_33 PF13592.6 RLN44468.1 - 0.011 15.3 0.1 0.038 13.6 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn helix DUF4785 PF16024.5 RLN44468.1 - 0.09 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4785) DUF4287 PF14117.6 RLN44468.1 - 0.16 12.1 0.1 0.3 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) ABC_tran PF00005.27 RLN44469.1 - 2.3e-41 141.5 0.1 5e-21 75.7 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN44469.1 - 1.2e-17 64.7 1.6 4.3e-05 23.5 0.1 4.4 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RLN44469.1 - 3.2e-11 43.1 0.6 0.0039 16.6 0.0 4.4 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain NACHT PF05729.12 RLN44469.1 - 1.2e-05 25.3 0.0 0.12 12.3 0.0 2.7 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.23 RLN44469.1 - 2.2e-05 24.5 0.1 0.064 13.3 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RLN44469.1 - 2.8e-05 24.1 0.0 0.052 13.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 RLN44469.1 - 3.9e-05 23.3 0.1 0.26 11.1 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN44469.1 - 9.2e-05 22.7 0.0 0.49 10.7 0.0 3.2 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 RLN44469.1 - 0.0002 20.4 1.1 0.1 11.6 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 RLN44469.1 - 0.00021 21.6 1.0 0.56 10.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain Roc PF08477.13 RLN44469.1 - 0.00025 21.2 0.0 1.2 9.4 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 RLN44469.1 - 0.00025 21.5 5.0 0.062 13.7 0.1 4.0 5 0 0 5 5 3 1 AAA ATPase domain AAA_24 PF13479.6 RLN44469.1 - 0.00026 20.8 0.1 0.81 9.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RLN44469.1 - 0.00027 21.5 0.0 1.6 9.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 RLN44469.1 - 0.00037 20.9 0.0 0.94 9.9 0.0 3.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 RLN44469.1 - 0.00044 20.4 0.0 0.27 11.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain CLASP_N PF12348.8 RLN44469.1 - 0.0005 19.7 1.0 0.0019 17.8 0.7 2.1 1 1 1 2 2 2 1 CLASP N terminal AAA_18 PF13238.6 RLN44469.1 - 0.00066 20.2 0.0 2.2 8.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 RLN44469.1 - 0.0024 18.0 3.2 0.038 14.1 0.0 3.4 3 1 0 3 3 3 1 Helicase HerA, central domain NB-ARC PF00931.22 RLN44469.1 - 0.0028 16.9 0.2 1.8 7.7 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain DUF815 PF05673.13 RLN44469.1 - 0.0033 16.6 0.1 0.22 10.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Thymidylate_kin PF02223.17 RLN44469.1 - 0.0039 16.9 1.5 12 5.5 0.0 3.4 3 0 0 3 3 3 0 Thymidylate kinase AAA_14 PF13173.6 RLN44469.1 - 0.0054 16.8 0.0 7.5 6.6 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 RLN44469.1 - 0.0054 16.5 0.0 5.3 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 RLN44469.1 - 0.0057 16.4 0.1 5.5 6.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 RLN44469.1 - 0.0073 15.9 0.0 1.5 8.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 RLN44469.1 - 0.0099 15.5 0.0 0.59 9.8 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 RLN44469.1 - 0.01 16.2 0.0 6.3 7.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase PduV-EutP PF10662.9 RLN44469.1 - 0.03 14.1 0.0 5.5 6.7 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 RLN44469.1 - 0.031 13.8 0.0 6.7 6.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 RLN44469.1 - 0.035 14.1 0.3 11 6.1 0.1 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_pol PF00940.19 RLN44469.1 - 0.075 11.9 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 DNA-dependent RNA polymerase Arf PF00025.21 RLN44469.1 - 0.1 12.1 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.19 RLN44469.1 - 0.11 12.1 0.5 7.7 6.1 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 RLN44469.1 - 0.13 12.1 0.3 12 5.6 0.0 3.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 RLN44469.1 - 0.13 12.3 0.0 0.43 10.6 0.0 2.0 1 0 0 1 1 1 0 Dynamin family 4HB PF17947.1 RLN44469.1 - 0.14 12.2 1.0 0.75 9.9 0.0 2.7 3 0 0 3 3 1 0 Four helical bundle domain HEAT PF02985.22 RLN44469.1 - 0.15 12.4 0.9 34 5.1 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat AAA_17 PF13207.6 RLN44469.1 - 0.32 11.4 7.0 10 6.6 0.1 4.3 4 0 0 4 4 4 0 AAA domain HEAT_EZ PF13513.6 RLN44469.1 - 0.48 11.0 5.2 8.7 7.0 0.4 4.3 4 0 0 4 4 3 0 HEAT-like repeat UNC45-central PF11701.8 RLN44469.1 - 0.68 9.9 4.0 1.5 8.8 2.6 2.1 1 1 1 2 2 2 0 Myosin-binding striated muscle assembly central NTPase_1 PF03266.15 RLN44469.1 - 1 9.2 3.7 14 5.5 0.1 2.9 3 0 0 3 3 2 0 NTPase Elicitin PF00964.17 RLN44470.1 - 1.1e-20 73.6 2.3 1.9e-20 72.7 2.3 1.5 1 0 0 1 1 1 1 Elicitin Methyltransf_3 PF01596.17 RLN44470.1 - 0.066 12.4 0.0 0.081 12.1 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase MULE PF10551.9 RLN44479.1 - 2.1e-12 47.3 0.2 8.3e-12 45.4 0.3 2.0 2 0 0 2 2 2 1 MULE transposase domain Serinc PF03348.15 RLN44479.1 - 0.0094 14.9 0.1 0.01 14.8 0.1 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) SET PF00856.28 RLN44480.1 - 8.7e-09 36.0 0.0 1.3e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 SET domain MFS_1 PF07690.16 RLN44489.1 - 1.2e-32 113.2 32.6 1.7e-32 112.8 32.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 RLN44491.1 - 7.6e-31 107.3 26.5 1.1e-30 106.8 26.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ABC_trans_CmpB PF06541.11 RLN44491.1 - 0.006 16.8 14.6 1.7 8.9 10.2 3.0 2 1 0 2 2 2 2 Putative ABC-transporter type IV Pantoate_transf PF02548.15 RLN44512.1 - 0.08 12.3 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase Ago_N_1 PF18351.1 RLN44513.1 - 0.07 13.6 0.5 0.18 12.3 0.1 1.8 2 0 0 2 2 2 0 Fungal Argonaute N-terminal domain Abhydrolase_4 PF08386.10 RLN44514.1 - 0.075 13.1 0.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 TAP-like protein tRNA-synt_1b PF00579.25 RLN44516.1 - 7.8e-72 242.1 0.0 1.1e-71 241.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 RLN44516.1 - 0.19 10.6 0.0 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) EGF_2 PF07974.13 RLN44517.1 - 9.8e-07 29.0 15.5 7.8e-05 23.0 3.7 2.8 2 0 0 2 2 2 2 EGF-like domain DUF3072 PF11272.8 RLN44517.1 - 0.032 14.1 0.2 0.07 13.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) Laminin_EGF PF00053.24 RLN44517.1 - 0.83 9.9 10.5 1.4 9.1 1.9 2.4 2 0 0 2 2 2 0 Laminin EGF domain EGF PF00008.27 RLN44517.1 - 4 7.8 12.4 0.92 9.9 2.1 2.7 3 0 0 3 3 3 0 EGF-like domain PseudoU_synth_2 PF00849.22 RLN44518.1 - 1.8e-23 83.4 0.0 5e-23 81.9 0.0 1.8 1 1 0 1 1 1 1 RNA pseudouridylate synthase Kinesin PF00225.23 RLN44519.1 - 2.8e-81 273.1 0.0 4.6e-81 272.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN44519.1 - 2.6e-15 56.7 0.0 1.8e-10 41.0 0.0 2.9 3 0 0 3 3 3 2 Microtubule binding AAA_22 PF13401.6 RLN44519.1 - 0.029 14.6 2.3 0.67 10.2 0.1 3.1 3 0 0 3 3 3 0 AAA domain PIF1 PF05970.14 RLN44519.1 - 0.1 11.8 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 PIF1-like helicase PhoH PF02562.16 RLN44519.1 - 0.13 11.7 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 RLN44519.1 - 0.2 12.0 0.0 0.2 12.0 0.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain DUF442 PF04273.13 RLN44519.1 - 0.24 11.5 0.9 1.5 8.9 0.1 2.3 2 0 0 2 2 2 0 Putative phosphatase (DUF442) Pox_A_type_inc PF04508.12 RLN44519.1 - 1.7 8.6 8.2 0.22 11.4 1.9 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat NOA36 PF06524.12 RLN44519.1 - 6 6.1 5.2 10 5.4 5.2 1.3 1 0 0 1 1 1 0 NOA36 protein Pantoate_ligase PF02569.15 RLN44520.1 - 3.2e-92 308.5 0.1 3.5e-92 308.4 0.1 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase FAD_syn PF06574.12 RLN44520.1 - 0.11 12.3 0.2 2 8.3 0.0 2.5 3 0 0 3 3 3 0 FAD synthetase HRDC PF00570.23 RLN44521.1 - 4.1e-15 55.5 0.0 5.9e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 HRDC domain RsdA_SigD_bd PF16751.5 RLN44521.1 - 0.066 13.5 0.4 0.16 12.2 0.1 1.8 2 0 0 2 2 2 0 Anti-sigma-D factor RsdA to sigma factor binding region Helicase_Sgs1 PF11408.8 RLN44521.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Sgs1 RecQ helicase Competence PF03772.16 RLN44534.1 - 0.015 14.6 0.2 0.12 11.6 0.0 1.9 2 0 0 2 2 2 0 Competence protein MARVEL PF01284.23 RLN44535.1 - 0.007 16.4 2.6 0.009 16.1 2.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain LRR_8 PF13855.6 RLN44536.1 - 3.4e-07 29.9 1.0 0.001 18.8 0.4 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RLN44536.1 - 4e-07 30.2 0.2 0.0075 16.7 0.3 2.8 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) PET PF06297.14 RLN44536.1 - 0.00044 20.5 1.4 0.0012 19.1 1.4 1.7 1 0 0 1 1 1 1 PET Domain LRR_1 PF00560.33 RLN44536.1 - 0.012 16.0 0.1 45 5.2 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 RLN44536.1 - 0.024 14.7 0.2 1.1e+02 3.3 0.0 4.4 3 1 1 4 4 4 0 Leucine Rich repeat Myosin_head PF00063.21 RLN44545.1 - 4.7e-164 547.3 1.1 5.3e-164 547.1 1.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 RLN44545.1 - 0.023 15.1 0.0 0.046 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 RLN44545.1 - 0.035 14.4 0.0 0.099 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_lid_6 PF17866.1 RLN44545.1 - 0.08 13.1 0.0 0.36 11.0 0.0 2.1 1 0 0 1 1 1 0 AAA lid domain T2SSE PF00437.20 RLN44545.1 - 0.086 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein HEAT PF02985.22 RLN44546.1 - 7.9e-10 38.1 6.1 2 8.9 0.0 6.8 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.6 RLN44546.1 - 2.9e-06 27.6 8.3 0.82 10.1 0.0 5.6 4 2 1 6 6 6 2 HEAT repeats Cnd1 PF12717.7 RLN44546.1 - 0.0003 20.9 0.2 1.1 9.3 0.0 3.8 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 RLN44546.1 - 0.0026 18.2 11.8 2.8 8.6 0.0 6.2 5 2 1 6 6 6 3 HEAT-like repeat RTP1_C1 PF10363.9 RLN44546.1 - 0.036 14.2 1.0 1.2 9.3 0.0 3.4 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Caerin_1 PF07440.12 RLN44546.1 - 0.086 12.9 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 Caerin 1 protein Vac14_Fab1_bd PF12755.7 RLN44546.1 - 0.88 10.2 5.3 10 6.8 0.0 4.4 5 1 0 5 5 5 0 Vacuolar 14 Fab1-binding region C2-C2_1 PF11618.8 RLN44547.1 - 0.0049 16.9 0.0 0.03 14.4 0.0 1.9 2 0 0 2 2 2 1 First C2 domain of RPGR-interacting protein 1 CAMSAP_CH PF11971.8 RLN44548.1 - 0.15 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 CAMSAP CH domain NMT_C PF02799.15 RLN44557.1 - 8.7e-79 263.9 0.0 1.5e-78 263.2 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 RLN44557.1 - 2.2e-75 251.9 0.0 4.1e-75 251.0 0.0 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Peroxidase_2 PF01328.17 RLN44557.1 - 0.027 15.0 0.1 0.083 13.4 0.0 1.8 2 0 0 2 2 2 0 Peroxidase, family 2 Acetyltransf_1 PF00583.25 RLN44557.1 - 0.051 13.8 0.0 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 RLN44557.1 - 0.058 13.5 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain NMT_C PF02799.15 RLN44558.1 - 2.3e-81 272.3 0.4 3.4e-81 271.8 0.4 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 RLN44558.1 - 7.6e-77 256.6 0.2 1.1e-75 252.9 0.0 2.1 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 RLN44558.1 - 0.0072 16.4 0.1 0.047 13.8 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RLN44558.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Thioredoxin PF00085.20 RLN44559.1 - 1e-13 51.1 0.0 4.6e-13 49.0 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 RLN44559.1 - 3.8e-07 30.2 0.0 0.00035 20.5 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain VWA PF00092.28 RLN44559.1 - 4.4e-07 30.3 0.0 3.5e-06 27.4 0.0 2.4 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA_2 PF13519.6 RLN44559.1 - 0.00045 20.8 0.0 0.0029 18.2 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain Thioredoxin_2 PF13098.6 RLN44559.1 - 0.058 13.9 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain HGTP_anticodon PF03129.20 RLN44560.1 - 2.6e-20 72.3 0.0 5.2e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 RLN44560.1 - 3.7e-10 40.1 0.0 5.8e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) zinc_ribbon_4 PF13717.6 RLN44560.1 - 0.31 11.0 1.7 2.9 7.9 0.4 2.6 3 0 0 3 3 3 0 zinc-ribbon domain Pet191_N PF10203.9 RLN44563.1 - 2.8e-22 78.8 6.6 3.1e-22 78.6 6.6 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 RLN44563.1 - 0.29 11.2 8.6 0.72 9.9 1.6 2.8 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like zf-RING_2 PF13639.6 RLN44564.1 - 2.6e-10 40.5 5.9 1.5e-09 38.1 5.9 2.4 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RLN44564.1 - 8.3e-10 38.8 2.7 2.6e-09 37.2 2.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 RLN44564.1 - 2.2e-05 24.2 2.4 2.2e-05 24.2 2.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RLN44564.1 - 4.4e-05 23.5 0.8 4.4e-05 23.5 0.8 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 RLN44564.1 - 5e-05 23.1 4.9 0.00025 20.8 4.9 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN44564.1 - 0.00027 20.9 1.7 0.00066 19.7 0.3 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN44564.1 - 0.00033 20.5 2.3 0.0012 18.8 2.3 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 RLN44564.1 - 0.0048 16.6 6.0 0.0048 16.6 6.0 3.5 3 1 0 3 3 3 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 RLN44564.1 - 0.0064 16.3 4.9 0.04 13.8 4.9 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN44564.1 - 0.013 15.3 1.7 0.036 13.9 1.6 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 PX PF00787.24 RLN44564.1 - 0.015 15.2 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 PX domain zf-C3HC4_4 PF15227.6 RLN44564.1 - 0.063 13.4 5.3 0.079 13.1 2.7 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 RLN44564.1 - 0.08 12.8 1.9 0.21 11.4 1.9 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 RLN44564.1 - 3.8 7.7 11.0 3.3 8.0 6.4 3.1 2 1 0 2 2 2 0 FANCL C-terminal domain DUF2367 PF10164.9 RLN44570.1 - 0.011 16.2 0.0 0.52 10.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) EB_dh PF09459.10 RLN44570.1 - 0.037 14.0 0.0 0.051 13.5 0.0 1.1 1 0 0 1 1 1 0 Ethylbenzene dehydrogenase HemY_N PF07219.13 RLN44570.1 - 1.6 8.9 4.0 0.79 9.9 1.0 1.9 2 0 0 2 2 2 0 HemY protein N-terminus R3H PF01424.22 RLN44571.1 - 2.6e-05 24.1 0.1 7.5e-05 22.6 0.1 1.7 2 0 0 2 2 2 1 R3H domain bZIP_1 PF00170.21 RLN44572.1 - 2.4e-09 37.1 13.4 2.4e-09 37.1 13.4 2.6 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 RLN44572.1 - 3.7e-08 33.3 11.2 3.7e-08 33.3 11.2 2.4 2 0 0 2 2 2 1 Basic region leucine zipper Atg14 PF10186.9 RLN44572.1 - 0.017 14.2 10.6 0.02 14.0 3.8 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 LTXXQ PF07813.12 RLN44572.1 - 0.052 14.3 0.5 0.052 14.3 0.5 3.0 2 2 0 2 2 2 0 LTXXQ motif family protein bZIP_Maf PF03131.17 RLN44572.1 - 0.97 10.0 16.4 0.08 13.5 8.7 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor GBP_C PF02841.14 RLN44572.1 - 2.5 7.4 9.5 1.6 8.1 4.8 2.1 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain CorA PF01544.18 RLN44572.1 - 8.9 5.5 8.7 3.4 6.9 0.3 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein PH PF00169.29 RLN44573.1 - 9.4e-10 39.0 0.0 2.1e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN44573.1 - 0.00078 19.7 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 RLN44573.1 - 0.016 15.6 3.5 0.13 12.7 0.1 3.6 3 1 0 3 3 3 0 Pleckstrin homology domain PH_6 PF15406.6 RLN44573.1 - 0.14 12.4 0.0 0.71 10.2 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain DUF4726 PF15855.5 RLN44573.1 - 0.4 10.9 2.3 1 9.6 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) HHH_8 PF14716.6 RLN44581.1 - 2.6e-19 69.3 0.3 7.2e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 Helix-hairpin-helix domain DUF2239 PF09998.9 RLN44581.1 - 0.022 14.6 0.1 0.042 13.6 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2239) LRR_8 PF13855.6 RLN44582.1 - 0.026 14.3 1.1 2.9 7.7 0.1 2.7 2 0 0 2 2 2 0 Leucine rich repeat NAD_kinase PF01513.21 RLN44583.1 - 8.3e-10 38.3 0.0 1.2e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 RLN44583.1 - 0.0071 16.0 0.9 0.015 14.9 0.9 1.6 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain Pkinase PF00069.25 RLN44585.1 - 5.2e-40 137.5 0.0 1.7e-39 135.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain CLASP_N PF12348.8 RLN44585.1 - 5.1e-20 72.0 4.7 9.7e-14 51.5 0.4 4.3 5 0 0 5 5 5 2 CLASP N terminal Pkinase_Tyr PF07714.17 RLN44585.1 - 5.4e-20 71.8 0.0 1.4e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Cohesin_HEAT PF12765.7 RLN44585.1 - 0.00014 22.1 0.2 1.2 9.5 0.0 4.1 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.6 RLN44585.1 - 0.00025 21.3 23.2 0.11 12.9 0.2 6.9 6 1 2 8 8 8 4 HEAT repeats Vac14_Fab1_bd PF12755.7 RLN44585.1 - 0.00037 21.0 5.5 1.5 9.4 0.1 5.6 6 1 0 6 6 6 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 RLN44585.1 - 0.0098 16.1 24.4 1.9 9.0 0.1 7.9 9 0 0 9 9 9 3 HEAT repeat Dopey_N PF04118.14 RLN44585.1 - 0.034 13.2 0.3 0.16 11.1 0.1 2.2 3 0 0 3 3 3 0 Dopey, N-terminal Creatininase PF02633.14 RLN44586.1 - 0.013 15.0 3.9 0.015 14.7 3.9 1.1 1 0 0 1 1 1 0 Creatinine amidohydrolase Plasmodium_Vir PF05795.11 RLN44586.1 - 0.92 8.9 4.4 1.1 8.6 4.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SET PF00856.28 RLN44586.1 - 1.2 9.5 4.5 1.9 8.9 4.5 1.3 1 1 0 1 1 1 0 SET domain XRN_M PF17846.1 RLN44586.1 - 2.2 7.1 9.5 2.6 6.9 9.5 1.0 1 0 0 1 1 1 0 Xrn1 helical domain DUF2992 PF11208.8 RLN44586.1 - 2.4 8.4 18.7 3.3 8.0 18.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DDHD PF02862.17 RLN44586.1 - 2.4 8.3 5.8 3.1 7.9 5.8 1.2 1 0 0 1 1 1 0 DDHD domain TFIIA PF03153.13 RLN44586.1 - 2.8 7.9 16.2 3.1 7.7 16.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Asp-B-Hydro_N PF05279.11 RLN44586.1 - 4.1 7.4 13.5 5.1 7.1 13.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region V_ATPase_I PF01496.19 RLN44586.1 - 4.4 5.1 9.5 4.8 5.0 9.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 RLN44586.1 - 5.5 6.3 20.4 6.5 6.0 20.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 RLN44586.1 - 5.7 5.4 9.5 6.7 5.2 9.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A ALMT PF11744.8 RLN44586.1 - 7.7 5.2 7.4 8.8 5.0 7.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Trypan_glycop PF00913.19 RLN44586.1 - 7.7 5.7 13.9 10 5.3 13.9 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) Spt20 PF12090.8 RLN44586.1 - 9.9 5.7 14.1 13 5.3 14.1 1.2 1 0 0 1 1 1 0 Spt20 family WW PF00397.26 RLN44587.1 - 1.4e-12 47.5 2.8 2.6e-05 24.2 0.5 2.5 2 0 0 2 2 2 2 WW domain FF PF01846.19 RLN44587.1 - 1.1e-09 38.3 0.3 6.3e-09 35.9 0.0 2.3 2 1 0 2 2 2 1 FF domain Glyco_hyd_101C PF17451.2 RLN44587.1 - 0.2 12.0 7.5 2.9 8.2 0.1 3.4 3 1 0 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain Spore_coat_CotO PF14153.6 RLN44587.1 - 3.5 7.5 16.5 0.95 9.4 12.9 1.9 2 0 0 2 2 2 0 Spore coat protein CotO Presenilin PF01080.17 RLN44587.1 - 7.2 5.3 4.7 12 4.5 4.7 1.3 1 0 0 1 1 1 0 Presenilin Gal-bind_lectin PF00337.22 RLN44650.1 - 8.8e-13 47.9 0.0 1.5e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Galactoside-binding lectin RRM_1 PF00076.22 RLN44650.1 - 1.7e-12 47.0 0.0 3.3e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pox_Ag35 PF03286.14 RLN44651.1 - 0.0044 16.8 1.8 0.0075 16.1 1.8 1.4 1 0 0 1 1 1 1 Pox virus Ag35 surface protein DUF2150 PF09920.9 RLN44651.1 - 0.031 14.3 1.8 0.12 12.4 2.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) DUF3397 PF11877.8 RLN44651.1 - 0.042 14.1 0.1 3.1 8.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3397) Vel1p PF10339.9 RLN44652.1 - 0.032 13.6 0.5 0.043 13.2 0.5 1.2 1 0 0 1 1 1 0 Yeast-specific zinc responsive SQAPI PF16845.5 RLN44652.1 - 0.069 13.5 0.1 0.49 10.8 0.1 2.1 1 1 0 1 1 1 0 Aspartic acid proteinase inhibitor Cystatin PF00031.21 RLN44652.1 - 0.074 13.3 0.1 0.11 12.8 0.1 1.4 1 1 0 1 1 1 0 Cystatin domain SNN_transmemb PF09049.10 RLN44652.1 - 0.11 12.5 3.1 0.37 10.8 0.6 2.3 2 0 0 2 2 2 0 Stannin transmembrane Topo-VIb_trans PF09239.11 RLN44653.1 - 0.00023 21.1 0.0 0.00037 20.4 0.0 1.3 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer DPM2 PF07297.12 RLN44654.1 - 4.3e-19 68.6 0.4 7.2e-19 67.9 0.4 1.2 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) UPF0113 PF03657.13 RLN44655.1 - 1.6e-24 85.9 0.1 5.1e-23 81.1 0.0 2.2 2 0 0 2 2 2 1 UPF0113 PUA domain UPF0113_N PF17833.1 RLN44655.1 - 7.1e-24 84.2 0.3 1.3e-23 83.3 0.3 1.4 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain Mito_carr PF00153.27 RLN44656.1 - 2.4e-62 206.9 5.3 1.9e-22 79.0 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mannosyl_trans3 PF11051.8 RLN44660.1 - 1.5e-14 54.0 0.0 1.7e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 Mannosyltransferase putative Totivirus_coat PF05518.11 RLN44698.1 - 0.087 10.9 1.7 0.11 10.6 1.7 1.1 1 0 0 1 1 1 0 Totivirus coat protein KIX_2 PF16987.5 RLN44698.1 - 0.11 12.5 0.3 0.26 11.3 0.1 1.8 1 1 1 2 2 2 0 KIX domain DUF3720 PF12517.8 RLN44698.1 - 0.22 12.5 4.7 0.33 11.9 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) KIX_2 PF16987.5 RLN44699.1 - 0.0023 17.9 0.1 0.0044 17.0 0.1 1.5 1 1 0 1 1 1 1 KIX domain Linker_histone PF00538.19 RLN44743.1 - 0.063 13.7 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 linker histone H1 and H5 family DUF3546 PF12066.8 RLN44805.1 - 8.5e-18 64.6 5.7 1.4e-17 63.8 5.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) DUF3283 PF11686.8 RLN44805.1 - 0.059 13.2 0.5 0.14 12.1 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3283) MARVEL PF01284.23 RLN44806.1 - 3.6e-06 27.1 7.4 5.4e-06 26.5 7.4 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4293 PF14126.6 RLN44806.1 - 3.8 7.8 7.2 7.2 6.8 1.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) Hexapep PF00132.24 RLN44813.1 - 4.9e-14 51.4 8.0 1.4e-08 34.1 3.3 3.2 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 RLN44813.1 - 7.2e-13 48.6 0.2 1.8e-12 47.3 0.1 1.6 2 0 0 2 2 2 1 Maltose acetyltransferase Hexapep_2 PF14602.6 RLN44813.1 - 2.7e-08 33.4 11.4 1.5e-06 27.9 4.2 3.3 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase PX PF00787.24 RLN44814.1 - 0.00018 21.4 0.2 0.00033 20.6 0.2 1.4 1 0 0 1 1 1 1 PX domain Pkinase PF00069.25 RLN44815.1 - 1.4e-49 168.9 0.0 1.9e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN44815.1 - 2.2e-44 151.7 0.0 2.9e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN44815.1 - 0.076 11.8 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF3746 PF12562.8 RLN44815.1 - 0.13 12.2 0.4 0.22 11.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3746) Pkinase PF00069.25 RLN44816.1 - 5.8e-48 163.6 0.0 7.5e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN44816.1 - 4.9e-43 147.3 0.0 6.3e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN44816.1 - 0.0057 15.5 0.0 0.008 15.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase GAF PF01590.26 RLN44817.1 - 0.017 15.7 0.0 0.025 15.2 0.0 1.3 1 0 0 1 1 1 0 GAF domain SpoVT_C PF15714.5 RLN44817.1 - 0.023 14.8 0.0 0.033 14.2 0.0 1.2 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor Pkinase PF00069.25 RLN44818.1 - 6.5e-48 163.4 0.0 9.8e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN44818.1 - 2.1e-40 138.6 0.0 2.8e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Podoplanin PF05808.11 RLN44818.1 - 0.062 13.4 0.3 0.12 12.4 0.3 1.5 1 0 0 1 1 1 0 Podoplanin TMEM51 PF15345.6 RLN44818.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 S1FA PF04689.13 RLN44818.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA Pkinase PF00069.25 RLN44819.1 - 2.1e-49 168.3 0.0 3e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN44819.1 - 1.1e-41 142.9 0.0 1.4e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4690 PF15756.5 RLN44819.1 - 0.00098 19.7 1.3 0.0033 18.0 1.3 1.9 1 0 0 1 1 1 1 Small Novel Rich in Cartilage EphA2_TM PF14575.6 RLN44819.1 - 0.0045 17.8 0.2 0.011 16.6 0.0 1.7 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 RLN44819.1 - 0.014 15.5 2.3 0.014 15.5 2.3 1.9 2 0 0 2 2 2 0 Podoplanin Amnionless PF14828.6 RLN44819.1 - 0.055 12.3 0.0 0.08 11.8 0.0 1.1 1 0 0 1 1 1 0 Amnionless PTP_tm PF18861.1 RLN44819.1 - 0.98 9.4 4.4 1.8 8.5 4.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J FeoB_associated PF12669.7 RLN44819.1 - 1.6 9.2 9.6 0.14 12.6 2.9 2.4 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein DDE_1 PF03184.19 RLN44862.1 - 1.7e-15 57.1 0.0 3e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 RLN44862.1 - 3.4e-06 26.9 0.0 0.067 12.9 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease TMEM171 PF15471.6 RLN44862.1 - 0.0095 15.0 0.1 0.023 13.7 0.0 1.5 2 0 0 2 2 2 1 Transmembrane protein family 171 HTH_Tnp_Tc5 PF03221.16 RLN44862.1 - 0.1 12.6 0.0 0.39 10.8 0.0 2.1 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain GshA PF08886.11 RLN44862.1 - 0.11 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Glutamate-cysteine ligase Fer2 PF00111.27 RLN44866.1 - 4.9e-12 45.6 0.2 8.4e-12 44.9 0.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 RLN44866.1 - 0.055 13.5 0.6 0.12 12.4 0.6 1.7 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Ion_trans PF00520.31 RLN44867.1 - 3.6e-18 65.7 7.3 4.9e-18 65.3 4.6 2.1 2 0 0 2 2 2 1 Ion transport protein cNMP_binding PF00027.29 RLN44867.1 - 3.5e-12 46.2 0.1 1.7e-11 44.0 0.1 2.1 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 RLN44867.1 - 1.5e-11 44.1 5.4 1.5e-11 44.1 5.4 1.9 2 0 0 2 2 2 1 Ion channel LETM1 PF07766.13 RLN44868.1 - 6.3e-52 176.6 0.1 8e-52 176.2 0.1 1.1 1 0 0 1 1 1 1 LETM1-like protein ABC2_membrane PF01061.24 RLN44869.1 - 3.4e-63 212.9 64.6 3.1e-32 111.7 28.1 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN44869.1 - 1.6e-16 61.0 0.0 2.8e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter PDR_CDR PF06422.12 RLN44869.1 - 1.7e-06 27.8 0.0 1.7e-06 27.8 0.0 4.0 4 0 0 4 4 3 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 RLN44869.1 - 1.1e-05 24.7 47.6 0.0034 16.6 16.0 2.7 2 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 RLN44869.1 - 0.00012 22.0 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN44869.1 - 0.0026 17.7 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase PDR_assoc PF08370.11 RLN44869.1 - 0.0037 17.0 19.4 0.12 12.1 0.1 4.8 4 0 0 4 4 4 2 Plant PDR ABC transporter associated AAA_29 PF13555.6 RLN44869.1 - 0.0059 16.3 0.7 0.013 15.3 0.7 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN44869.1 - 0.041 14.4 0.0 0.087 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RLN44869.1 - 0.043 14.2 0.5 0.11 12.9 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain AcrZ PF10766.9 RLN44869.1 - 0.11 12.1 0.9 6.6 6.4 0.1 2.8 2 0 0 2 2 2 0 Multidrug efflux pump-associated protein AcrZ SMC_N PF02463.19 RLN44869.1 - 0.15 11.5 0.0 0.34 10.3 0.0 1.5 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Bac_export_2 PF01312.19 RLN44869.1 - 4.6 6.4 12.8 0.085 12.0 3.4 2.4 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family ubiquitin PF00240.23 RLN44870.1 - 1.9e-10 40.3 0.0 3.7e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RLN44870.1 - 0.00023 20.9 0.0 0.00081 19.2 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 RLN44870.1 - 0.00037 21.1 0.0 0.0007 20.2 0.0 1.5 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD SKN1 PF03935.15 RLN44871.1 - 1.8e-47 161.9 13.2 6.2e-30 104.1 4.2 4.1 3 2 0 3 3 3 2 Beta-glucan synthesis-associated protein (SKN1) DUF2269 PF10027.9 RLN44871.1 - 0.045 13.8 0.0 0.071 13.2 0.0 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) OAD_gamma PF04277.13 RLN44871.1 - 0.095 13.3 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Dynein_C PF18199.1 RLN44872.1 - 9.7e-102 340.3 0.9 2.3e-101 339.1 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 RLN44872.1 - 2.1e-101 338.6 0.0 3.4e-101 337.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RLN44872.1 - 1.4e-84 282.6 6.1 7.5e-84 280.3 0.0 3.1 3 0 0 3 3 3 2 ATP-binding dynein motor region AAA_lid_11 PF18198.1 RLN44872.1 - 2e-51 174.0 0.0 4e-51 173.1 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RLN44872.1 - 2.1e-47 160.1 0.0 2e-43 147.2 0.0 2.9 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 RLN44872.1 - 1.8e-41 142.3 15.0 3.1e-41 141.5 15.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 RLN44872.1 - 7.2e-16 58.2 0.5 3.7e-15 55.9 0.1 2.5 3 0 0 3 3 3 1 AAA+ lid domain Ribosomal_L27e PF01777.18 RLN44872.1 - 6.3 7.2 6.5 0.63 10.4 0.2 2.6 2 0 0 2 2 2 0 Ribosomal L27e protein family Peptidase_M41 PF01434.18 RLN44873.1 - 3.9e-62 209.5 0.2 7.3e-62 208.6 0.2 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 RLN44873.1 - 6e-44 149.7 0.0 1.2e-43 148.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RLN44873.1 - 2.6e-12 46.3 0.2 2.6e-12 46.3 0.2 3.1 3 0 0 3 3 3 1 AAA+ lid domain AAA_5 PF07728.14 RLN44873.1 - 1.5e-05 25.0 0.0 5.1e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RLN44873.1 - 4.5e-05 23.2 0.0 0.00012 21.9 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 RLN44873.1 - 7.8e-05 23.1 2.9 0.0013 19.1 0.1 2.9 2 1 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 RLN44873.1 - 9.9e-05 21.7 0.0 0.00018 20.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 RLN44873.1 - 0.00017 21.9 0.2 0.069 13.4 0.1 2.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RLN44873.1 - 0.0037 17.0 0.0 0.01 15.6 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 RLN44873.1 - 0.0071 16.9 0.0 0.021 15.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 RLN44873.1 - 0.0095 16.2 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 RLN44873.1 - 0.02 14.3 0.4 0.047 13.1 0.4 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 RLN44873.1 - 0.025 14.7 0.0 0.054 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 RLN44873.1 - 0.026 14.5 0.0 0.097 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 RLN44873.1 - 0.032 14.6 0.1 0.12 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 RLN44873.1 - 0.033 14.2 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 RLN44873.1 - 0.07 12.8 0.0 0.22 11.2 0.0 1.9 1 1 1 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 RLN44873.1 - 0.077 12.3 0.2 0.4 10.0 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_2 PF07724.14 RLN44873.1 - 0.093 12.8 0.0 0.37 10.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 RLN44873.1 - 0.096 12.3 0.1 0.48 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RLN44873.1 - 0.12 11.9 0.2 0.72 9.3 0.2 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 RLN44873.1 - 0.17 11.8 0.5 0.5 10.3 0.1 1.9 2 0 0 2 2 2 0 NACHT domain Ion_trans PF00520.31 RLN44887.1 - 4.2e-146 484.6 67.3 2.8e-45 154.5 11.6 4.3 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 RLN44887.1 - 1.1e-09 37.5 55.2 1.7e-05 23.7 7.7 7.1 6 3 0 7 7 7 5 Polycystin cation channel SR-25 PF10500.9 RLN44887.1 - 0.00037 20.2 8.9 0.00037 20.2 8.9 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein SelP_N PF04592.14 RLN44887.1 - 2.2 7.7 13.2 3.9 6.8 13.2 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DHC_N2 PF08393.13 RLN44888.1 - 1.7e-13 50.5 0.0 1.5e-12 47.3 0.0 2.3 1 1 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_22 PF13401.6 RLN44888.1 - 1.1e-08 35.5 0.0 0.0072 16.6 0.0 4.1 3 0 0 3 3 3 2 AAA domain AAA_6 PF12774.7 RLN44888.1 - 1.1e-08 34.4 0.0 0.00081 18.4 0.2 4.2 3 1 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 RLN44888.1 - 7e-06 25.7 0.0 0.048 13.2 0.0 3.3 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_8 PF12780.7 RLN44888.1 - 1.9e-05 24.1 0.0 0.0044 16.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_33 PF13671.6 RLN44888.1 - 0.00024 21.3 0.4 0.6 10.3 0.0 4.5 4 0 0 4 4 3 1 AAA domain AAA PF00004.29 RLN44888.1 - 0.00031 21.2 0.0 1.8 9.0 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 RLN44888.1 - 0.0016 18.1 0.1 0.42 10.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN44888.1 - 0.0089 16.4 0.0 0.0089 16.4 0.0 8.0 8 0 0 8 8 7 2 AAA ATPase domain ABC_tran PF00005.27 RLN44888.1 - 0.017 15.6 0.0 4.3 7.8 0.0 3.0 2 0 0 2 2 2 0 ABC transporter MRF_C1 PF13887.6 RLN44888.1 - 0.019 14.1 0.4 0.052 12.7 0.4 1.8 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 AAA_18 PF13238.6 RLN44888.1 - 0.022 15.3 0.0 1.8 9.1 0.0 3.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RLN44888.1 - 0.025 14.5 1.7 10 6.0 0.0 4.5 5 0 0 5 5 5 0 NACHT domain AAA_24 PF13479.6 RLN44888.1 - 0.042 13.6 0.0 2 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 RLN44888.1 - 0.14 12.5 0.1 25 5.2 0.0 3.6 4 0 0 4 4 4 0 AAA domain S1 PF00575.23 RLN44889.1 - 9.9e-17 61.1 2.4 1.2e-11 44.8 1.3 3.6 3 1 1 4 4 4 2 S1 RNA binding domain TPR_19 PF14559.6 RLN44889.1 - 4.3e-08 33.5 1.6 0.0028 18.1 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat Suf PF05843.14 RLN44889.1 - 6.1e-07 29.7 1.3 6.1e-07 29.7 1.3 3.9 1 1 2 4 4 3 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 RLN44889.1 - 2.6e-05 24.7 8.2 0.52 11.3 0.0 5.7 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 RLN44889.1 - 0.0015 19.1 2.3 0.076 13.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat PCB_OB PF17092.5 RLN44889.1 - 0.0019 18.9 0.5 3 8.6 0.0 4.2 1 1 3 4 4 4 1 Penicillin-binding protein OB-like domain TPR_16 PF13432.6 RLN44889.1 - 0.0025 18.4 1.2 0.022 15.4 0.2 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat Lin-8 PF03353.15 RLN44889.1 - 0.7 9.4 11.7 1.3 8.6 11.7 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist BUD22 PF09073.10 RLN44889.1 - 1.5 8.1 31.9 2.6 7.3 31.9 1.3 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 RLN44889.1 - 3.5 6.3 12.0 5.6 5.6 12.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GET2 PF08690.10 RLN44889.1 - 5 6.7 10.0 8.9 5.9 10.0 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 SBP_bac_5 PF00496.22 RLN44923.1 - 0.023 13.7 0.1 0.029 13.3 0.1 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle DEAD PF00270.29 RLN44925.1 - 3.8e-06 26.8 0.4 0.014 15.2 0.1 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN44925.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.8 1 1 0 1 1 1 0 Helicase conserved C-terminal domain CBS PF00571.28 RLN44925.1 - 0.057 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 CBS domain IPK PF03770.16 RLN44936.1 - 5.2e-43 147.2 0.0 7.2e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Rsm22 PF09243.10 RLN44937.1 - 3.9e-41 141.1 0.0 5.9e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 RLN44937.1 - 1.4e-09 38.0 0.0 4.3e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN44937.1 - 1.2e-07 32.4 0.0 7.1e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 RLN44937.1 - 2e-05 25.2 0.0 5.6e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN44937.1 - 0.0027 17.5 0.0 0.059 13.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_PK PF05891.12 RLN44937.1 - 0.07 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase MTS PF05175.14 RLN44937.1 - 0.093 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 RLN44937.1 - 0.099 13.3 0.0 0.44 11.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DUF1478 PF07349.11 RLN44937.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1478) Nop25 PF09805.9 RLN44965.1 - 1.3e-11 45.1 23.9 1.3e-11 45.1 23.9 2.7 1 1 1 2 2 2 1 Nucleolar protein 12 (25kDa) CENP-B_dimeris PF09026.10 RLN44965.1 - 0.63 10.5 16.3 1.6 9.1 1.8 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain GREB1 PF15782.5 RLN44965.1 - 1.2 6.2 4.6 1.4 5.9 4.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FAM176 PF14851.6 RLN44965.1 - 2.7 7.6 10.3 2 8.1 4.2 2.3 2 0 0 2 2 2 0 FAM176 family DUF3740 PF12548.8 RLN44965.1 - 5.1 7.5 10.2 0.12 12.8 1.9 2.2 2 0 0 2 2 2 0 Sulfatase protein GRP PF07172.11 RLN44965.1 - 6.5 7.5 18.2 1.4 9.7 3.4 3.5 3 0 0 3 3 3 0 Glycine rich protein family Pkinase PF00069.25 RLN44966.1 - 1.5e-18 67.2 0.0 1.6e-12 47.3 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain HEAT PF02985.22 RLN44966.1 - 4.4e-13 48.3 7.3 0.23 11.8 0.0 6.6 6 0 0 6 6 6 4 HEAT repeat WD40 PF00400.32 RLN44966.1 - 4.7e-11 43.0 7.3 0.00034 21.4 0.0 6.7 6 0 0 6 6 6 1 WD domain, G-beta repeat HEAT_2 PF13646.6 RLN44966.1 - 6e-08 33.0 0.3 0.018 15.4 0.0 5.7 3 2 3 6 6 6 2 HEAT repeats Pkinase_Tyr PF07714.17 RLN44966.1 - 7.9e-06 25.3 0.0 0.00033 20.0 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase HEAT_EZ PF13513.6 RLN44966.1 - 0.00029 21.3 0.3 0.13 12.8 0.1 3.9 3 0 0 3 3 3 1 HEAT-like repeat ANAPC4_WD40 PF12894.7 RLN44966.1 - 0.0011 19.2 0.5 1.8 8.9 0.1 3.7 3 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Tti2 PF10521.9 RLN44966.1 - 0.0024 17.5 0.1 0.01 15.4 0.0 2.1 2 0 0 2 2 2 1 Tti2 family APH PF01636.23 RLN44966.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Nup160 PF11715.8 RLN44966.1 - 0.057 12.1 1.8 0.17 10.5 0.2 2.4 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Arcadin_1 PF18653.1 RLN44966.1 - 0.14 12.2 0.1 0.46 10.6 0.1 1.9 1 0 0 1 1 1 0 Arcadin 1 TMCO5 PF14992.6 RLN44966.1 - 1.1 8.7 7.6 2.6 7.6 7.6 1.5 1 0 0 1 1 1 0 TMCO5 family Nipped-B_C PF12830.7 RLN44966.1 - 9.3 6.1 10.1 0.51 10.2 0.9 2.5 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus Tcp10_C PF07202.13 RLN44967.1 - 1.2e-31 110.0 0.3 1.2e-31 110.0 0.3 1.9 2 0 0 2 2 2 1 T-complex protein 10 C-terminus XhlA PF10779.9 RLN44967.1 - 0.67 10.2 7.4 1.8 8.9 1.1 2.8 2 0 0 2 2 2 0 Haemolysin XhlA GBP PF02263.19 RLN44969.1 - 1.8e-65 220.8 0.0 2.8e-65 220.2 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 RLN44969.1 - 6.3e-16 58.6 8.6 1.8e-10 40.7 0.0 2.8 2 1 0 2 2 2 2 Guanylate-binding protein, C-terminal domain PH PF00169.29 RLN44969.1 - 5.5e-08 33.3 0.0 1.1e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN44969.1 - 0.0019 18.6 0.1 0.06 13.8 0.1 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain UNC45-central PF11701.8 RLN44969.1 - 0.014 15.3 0.0 0.067 13.1 0.0 2.1 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central Muted PF14942.6 RLN44969.1 - 0.3 11.4 5.4 0.79 10.1 5.4 1.7 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein NDUFB10 PF10249.9 RLN44970.1 - 0.0021 18.6 0.2 0.0027 18.2 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Elicitin PF00964.17 RLN44972.1 - 1.6e-21 76.2 1.8 2.9e-21 75.4 1.8 1.4 1 0 0 1 1 1 1 Elicitin PT PF04886.12 RLN44972.1 - 4.8e-08 32.4 40.7 0.00024 20.6 36.3 3.1 2 1 0 2 2 2 1 PT repeat DAGK_cat PF00781.24 RLN44973.1 - 2.1e-21 75.9 0.2 2.9e-21 75.4 0.2 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SNF2_N PF00176.23 RLN44974.1 - 2.5e-61 207.3 0.0 4.3e-61 206.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.25 RLN44974.1 - 1.3e-07 31.4 7.0 1.3e-07 31.4 7.0 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN44974.1 - 4e-06 27.0 6.9 4e-06 27.0 6.9 2.7 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 RLN44974.1 - 7e-06 26.0 3.3 2.3e-05 24.3 3.3 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RLN44974.1 - 7.8e-06 25.6 8.0 2.6e-05 24.0 8.0 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN44974.1 - 1.6e-05 24.8 7.3 1.6e-05 24.8 7.3 2.6 2 0 0 2 2 2 1 zinc-RING finger domain PHD PF00628.29 RLN44974.1 - 3.3e-05 23.7 1.6 3.3e-05 23.7 1.6 3.4 3 0 0 3 3 3 1 PHD-finger zf-C3HC4_3 PF13920.6 RLN44974.1 - 0.00015 21.5 10.5 0.00015 21.5 10.5 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RLN44974.1 - 0.00067 19.8 5.9 0.0024 18.0 5.9 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RLN44974.1 - 0.0019 18.0 9.2 0.0059 16.5 9.2 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 RLN44974.1 - 0.036 13.8 6.1 0.034 13.9 4.0 2.1 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_4 PF14570.6 RLN44974.1 - 0.16 11.8 7.0 0.67 9.8 7.0 2.1 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain HTH_Tnp_Tc5 PF03221.16 RLN44975.1 - 3.2e-11 43.1 1.3 5.2e-11 42.4 0.0 2.1 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 RLN44975.1 - 6.9e-07 29.1 0.0 1.6e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.20 RLN44975.1 - 0.0042 17.4 0.7 0.014 15.7 0.1 2.1 2 0 0 2 2 2 1 Transposase BrkDBD PF09607.10 RLN44975.1 - 0.0078 16.0 0.0 0.036 13.9 0.0 2.2 2 0 0 2 2 2 1 Brinker DNA-binding domain HTH_28 PF13518.6 RLN44975.1 - 0.022 14.9 0.3 0.24 11.6 0.1 2.9 2 1 1 3 3 3 0 Helix-turn-helix domain CENP-B_N PF04218.13 RLN44975.1 - 0.027 14.1 0.0 0.075 12.7 0.0 1.9 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain PK PF00224.21 RLN44979.1 - 0.11 11.4 0.0 0.24 10.3 0.0 1.5 1 1 0 1 1 1 0 Pyruvate kinase, barrel domain Pribosyltran_N PF13793.6 RLN45030.1 - 7e-19 67.9 0.7 7.7e-18 64.5 0.3 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 RLN45030.1 - 7.5e-17 62.0 1.9 7.1e-10 39.2 0.0 2.8 3 1 0 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 RLN45030.1 - 3.6e-12 46.1 0.2 1.1e-11 44.5 0.1 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 RLN45030.1 - 0.078 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Pkinase PF00069.25 RLN45032.1 - 2.3e-46 158.3 0.0 3.7e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN45032.1 - 3.3e-19 69.2 0.0 5.6e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.14 RLN45032.1 - 3.9e-09 36.5 0.1 1.1e-08 35.1 0.1 1.8 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.6 RLN45032.1 - 1.5e-07 31.0 0.0 3.6e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN45032.1 - 0.0095 15.9 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN45032.1 - 0.029 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family KA1 PF02149.19 RLN45032.1 - 0.038 13.8 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinase associated domain 1 Choline_kinase PF01633.20 RLN45032.1 - 0.044 13.4 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF846 PF05832.12 RLN45033.1 - 8.5e-45 152.2 16.3 1.7e-35 122.1 0.5 2.5 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF846) FxsA PF04186.13 RLN45033.1 - 0.23 11.6 3.8 0.99 9.6 1.9 2.4 2 0 0 2 2 2 0 FxsA cytoplasmic membrane protein MAP17 PF15807.5 RLN45033.1 - 1.6 9.0 4.1 0.54 10.5 0.4 2.0 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 cNMP_binding PF00027.29 RLN45034.1 - 3.1e-48 161.8 0.1 2e-12 47.0 0.0 5.6 5 0 0 5 5 5 5 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN45034.1 - 7.5e-24 84.3 38.4 5.3e-10 38.9 7.8 4.5 4 0 0 4 4 4 4 Ion transport protein Ion_trans_2 PF07885.16 RLN45034.1 - 3.9 7.5 17.2 0.15 12.0 0.6 4.6 4 0 0 4 4 4 0 Ion channel cobW PF02492.19 RLN45035.1 - 1.1e-50 171.6 0.0 1.9e-50 170.9 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 RLN45035.1 - 5.9e-14 51.8 0.0 1.5e-13 50.4 0.0 1.8 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain TsaE PF02367.17 RLN45035.1 - 0.005 16.8 0.2 0.018 15.0 0.1 1.9 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 RLN45035.1 - 0.055 13.4 0.0 3.5 7.5 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase MobB PF03205.14 RLN45035.1 - 0.063 13.2 0.1 2.1 8.2 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 RLN45035.1 - 0.11 12.9 0.0 0.34 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain CLASP_N PF12348.8 RLN45036.1 - 2.1e-06 27.5 0.5 4.3e-06 26.5 0.1 1.6 2 0 0 2 2 2 1 CLASP N terminal ABC_tran_CTD PF16326.5 RLN45044.1 - 0.02 15.1 2.9 0.02 15.1 2.9 4.6 6 0 0 6 6 6 0 ABC transporter C-terminal domain Golgin_A5 PF09787.9 RLN45044.1 - 0.024 14.1 12.4 0.066 12.7 12.4 1.7 1 0 0 1 1 1 0 Golgin subfamily A member 5 TMCO5 PF14992.6 RLN45044.1 - 1.4 8.5 11.7 0.32 10.5 4.0 2.4 1 1 1 2 2 2 0 TMCO5 family Trimer_CC PF08954.11 RLN45044.1 - 2.5 7.7 9.9 4.4 6.9 0.2 4.6 4 0 0 4 4 4 0 Trimerisation motif Cep57_MT_bd PF06657.13 RLN45044.1 - 3.4 8.2 14.7 0.99 9.9 0.1 4.4 4 1 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 FAD_binding_2 PF00890.24 RLN45045.1 - 1.2e-67 228.9 4.5 8.7e-66 222.7 0.2 2.7 2 1 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 RLN45045.1 - 0.001 18.4 1.5 5.7 6.1 0.0 4.1 4 0 0 4 4 4 1 Thi4 family NAD_binding_8 PF13450.6 RLN45045.1 - 0.0032 17.7 1.4 0.12 12.6 1.0 3.3 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.19 RLN45045.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase GIDA PF01134.22 RLN45045.1 - 0.053 12.6 0.7 11 5.0 0.0 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A DAO PF01266.24 RLN45045.1 - 0.06 12.9 4.7 1.5 8.3 4.7 3.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase PGAP1 PF07819.13 RLN45046.1 - 1.2e-51 175.7 0.0 1.9e-51 175.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 RLN45046.1 - 0.00091 19.9 1.5 0.0022 18.7 1.5 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family MaoC_dehydrat_N PF13452.6 RLN45046.1 - 0.027 14.6 0.0 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase MSP1a PF11670.8 RLN45046.1 - 0.032 13.5 0.0 0.097 12.0 0.0 1.8 2 0 0 2 2 2 0 Major surface protein 1a (MSP1a) V_ATPase_I PF01496.19 RLN45046.1 - 0.37 8.7 1.7 0.55 8.1 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4834 PF16118.5 RLN45046.1 - 0.52 11.3 3.7 0.99 10.4 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) NPR3 PF03666.13 RLN45046.1 - 3.1 6.5 8.6 4.6 5.9 8.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SUI1 PF01253.22 RLN45047.1 - 9.6e-12 45.3 0.2 1.8e-11 44.4 0.2 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 RLN45047.1 - 3.7e-07 30.7 0.0 1.1e-06 29.2 0.0 1.9 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 RLN45047.1 - 0.0025 17.7 0.0 0.0084 16.1 0.0 2.0 1 0 0 1 1 1 1 PUA domain Kin17_mid PF10357.9 RLN45047.1 - 0.016 15.1 2.2 0.021 14.8 0.2 2.1 1 1 1 2 2 2 0 Domain of Kin17 curved DNA-binding protein Pkinase PF00069.25 RLN45048.1 - 7.1e-38 130.5 0.0 2e-25 89.7 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN45048.1 - 2e-37 128.9 0.0 3.1e-23 82.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase DEP PF00610.21 RLN45048.1 - 0.0017 18.4 0.1 0.0036 17.3 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) APH PF01636.23 RLN45048.1 - 0.0086 16.0 0.4 0.0086 16.0 0.4 2.4 2 2 0 2 2 2 1 Phosphotransferase enzyme family ABC1 PF03109.16 RLN45048.1 - 0.047 13.8 0.1 0.092 12.9 0.1 1.4 1 0 0 1 1 1 0 ABC1 family Seadorna_VP7 PF07387.11 RLN45048.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4205 PF13898.6 RLN45049.1 - 8.2e-75 251.9 0.0 9.1e-75 251.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) zf-Tim10_DDP PF02953.15 RLN45125.1 - 6.8e-16 57.7 0.7 8.7e-16 57.3 0.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Methyltransf_31 PF13847.6 RLN45126.1 - 1.6e-08 34.5 0.0 1.9e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN45126.1 - 2.8e-07 31.1 0.0 4.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 RLN45126.1 - 5.1e-07 29.3 0.0 6e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 RLN45126.1 - 1.1e-05 25.0 0.0 1.5e-05 24.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DOT1 PF08123.13 RLN45126.1 - 0.00015 21.3 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_11 PF08241.12 RLN45126.1 - 0.001 19.7 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 RLN45126.1 - 0.0011 18.7 0.0 0.0016 18.1 0.0 1.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.14 RLN45126.1 - 0.0021 17.6 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 RLN45126.1 - 0.0031 16.6 0.0 0.0037 16.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 RLN45126.1 - 0.016 15.1 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 RLN45126.1 - 0.026 14.0 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase MetW PF07021.12 RLN45126.1 - 0.028 14.0 0.1 0.038 13.6 0.1 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 RLN45126.1 - 0.046 13.7 0.0 0.062 13.2 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_20 PF12147.8 RLN45126.1 - 0.085 12.0 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase KRAP_IP3R_bind PF14722.6 RLN45126.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.7 2 0 0 2 2 2 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain Methyltransf_12 PF08242.12 RLN45126.1 - 0.14 12.9 0.0 0.25 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 RLN45126.1 - 0.22 10.9 0.0 0.28 10.6 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB PPR_3 PF13812.6 RLN45127.1 - 0.045 13.8 0.1 0.7 10.0 0.0 2.5 1 1 1 2 2 2 0 Pentatricopeptide repeat domain DUF1598 PF07643.11 RLN45127.1 - 0.074 13.3 0.0 0.35 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1598) PPR PF01535.20 RLN45128.1 - 0.0083 16.3 1.8 51 4.4 0.0 5.6 6 0 0 6 6 6 0 PPR repeat Corazonin PF17308.2 RLN45128.1 - 0.024 15.0 1.1 0.095 13.1 0.2 2.3 2 0 0 2 2 2 0 Pro-corazonin PPR_2 PF13041.6 RLN45128.1 - 0.098 12.9 0.0 18 5.6 0.0 3.3 3 0 0 3 3 3 0 PPR repeat family NOA36 PF06524.12 RLN45128.1 - 3.8 6.7 5.8 6.8 5.9 5.8 1.3 1 0 0 1 1 1 0 NOA36 protein DUF3037 PF11236.8 RLN45129.1 - 0.042 14.3 1.6 0.042 14.3 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) GAS PF13851.6 RLN45129.1 - 1.4 8.2 22.6 1.1 8.6 5.4 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Nkap_C PF06047.11 RLN45129.1 - 1.8 8.7 7.1 0.44 10.7 3.2 2.0 2 1 0 2 2 2 0 NF-kappa-B-activating protein C-terminal domain APG6_N PF17675.1 RLN45129.1 - 1.9 9.0 26.1 0.46 11.0 14.2 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF724 PF05266.14 RLN45129.1 - 2.8 7.7 13.8 5.3 6.8 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DEAD PF00270.29 RLN45151.1 - 2.4e-14 53.5 0.2 8.3e-13 48.5 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN45151.1 - 4.5e-14 52.7 0.0 1.2e-13 51.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 RLN45151.1 - 1.5e-08 34.8 0.0 1.5e-08 34.8 0.0 3.1 4 0 0 4 4 2 1 Helicase associated domain (HA2) RWD PF05773.22 RLN45151.1 - 5.5e-07 29.9 0.1 1.7e-06 28.3 0.1 1.9 1 1 0 1 1 1 1 RWD domain AAA_19 PF13245.6 RLN45151.1 - 0.00021 21.7 0.0 0.0008 19.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RLN45151.1 - 0.00067 19.9 0.2 0.0025 18.1 0.2 2.0 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 RLN45151.1 - 0.00068 18.8 0.0 0.0023 17.1 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein UBA PF00627.31 RLN45151.1 - 0.002 18.0 0.2 0.52 10.3 0.0 3.0 3 0 0 3 3 2 1 UBA/TS-N domain DnaB_2 PF07261.11 RLN45151.1 - 0.0074 16.0 0.0 0.024 14.4 0.0 1.9 1 0 0 1 1 1 1 Replication initiation and membrane attachment PhoH PF02562.16 RLN45151.1 - 0.017 14.5 0.7 0.039 13.4 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein FtsK_SpoIIIE PF01580.18 RLN45151.1 - 0.027 13.8 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family ResIII PF04851.15 RLN45151.1 - 0.043 13.8 0.0 0.17 11.9 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ATPase PF06745.13 RLN45151.1 - 0.047 13.0 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 RLN45151.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 RLN45151.1 - 0.067 13.2 0.1 1.4 9.0 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 RLN45151.1 - 0.077 12.7 2.2 0.13 12.0 0.0 2.4 3 0 0 3 3 2 0 AAA domain Rad17 PF03215.15 RLN45151.1 - 0.089 12.7 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain SRP54 PF00448.22 RLN45151.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF4484 PF14831.6 RLN45151.1 - 0.25 11.4 5.2 0.92 9.5 5.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) IATP PF04568.12 RLN45151.1 - 0.34 11.4 6.5 0.68 10.4 0.7 2.8 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP AAA_16 PF13191.6 RLN45151.1 - 1.4 9.2 4.7 6.1 7.2 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain Ras PF00071.22 RLN45167.1 - 1.9e-50 170.6 0.1 2.4e-50 170.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN45167.1 - 6.5e-23 81.2 0.0 1.1e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN45167.1 - 3.3e-07 29.9 0.0 4.2e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RLN45167.1 - 0.0027 17.6 0.0 0.2 11.5 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase adh_short PF00106.25 RLN45170.1 - 2.4e-09 37.0 0.0 1.4e-08 34.4 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN45170.1 - 0.00011 21.8 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN45170.1 - 0.0049 16.8 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 RLN45170.1 - 0.0056 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Catalase_C PF18011.1 RLN45170.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain found in long catalases GTP_EFTU_D3 PF03143.17 RLN45171.1 - 3.3e-42 143.3 0.0 6.2e-42 142.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 RLN45171.1 - 4.9e-13 49.3 0.1 9.9e-13 48.3 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 RLN45171.1 - 0.084 12.8 1.2 0.15 12.0 0.2 1.9 2 0 0 2 2 2 0 Elongation factor Tu domain 4 adh_short PF00106.25 RLN45172.1 - 3.3e-07 29.9 0.0 2.6e-06 27.0 0.0 2.1 1 1 1 2 2 2 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.8 RLN45172.1 - 0.0064 16.2 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.6 RLN45172.1 - 0.0081 15.7 0.0 0.029 13.9 0.0 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN45172.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 KR domain Peptidase_A22B PF04258.13 RLN45200.1 - 3.1e-56 191.0 4.5 1.9e-55 188.4 4.5 1.9 1 1 0 1 1 1 1 Signal peptide peptidase Orf78 PF06024.12 RLN45200.1 - 1.1 9.5 3.1 2.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Orf78 (ac78) CcmH PF03918.14 RLN45200.1 - 2.7 7.3 5.3 1.3 8.3 0.1 3.0 2 1 1 3 3 3 0 Cytochrome C biogenesis protein PKD_channel PF08016.12 RLN45202.1 - 9.1e-09 34.5 12.4 9.1e-09 34.5 12.4 1.6 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 RLN45202.1 - 0.00031 20.1 19.1 0.00053 19.3 17.3 2.1 1 1 1 2 2 2 1 Ion transport protein DAO PF01266.24 RLN45220.1 - 3e-38 132.3 0.4 1.3e-37 130.2 0.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RLN45220.1 - 0.00012 21.5 0.0 0.00033 20.0 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RLN45220.1 - 0.0089 14.8 0.0 0.019 13.7 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein DUF4407 PF14362.6 RLN45221.1 - 2 7.7 9.6 0.1 12.0 2.8 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) CorA PF01544.18 RLN45222.1 - 1.6e-46 159.0 0.8 2.7e-39 135.3 0.0 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein ATP_bind_2 PF03668.15 RLN45222.1 - 2.6e-05 23.6 0.0 4.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 P-loop ATPase protein family EF-hand_7 PF13499.6 RLN45222.1 - 0.012 16.1 0.1 0.025 15.0 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 RLN45222.1 - 0.019 14.5 0.2 0.036 13.6 0.2 1.5 1 0 0 1 1 1 0 EF hand Jas PF16135.5 RLN45272.1 - 7.3e-08 32.5 13.4 3.6e-05 23.8 0.2 3.2 3 0 0 3 3 3 2 TPL-binding domain in jasmonate signalling PHD PF00628.29 RLN45272.1 - 0.0066 16.3 6.3 0.0066 16.3 6.3 3.8 5 0 0 5 5 5 1 PHD-finger Zf_RING PF16744.5 RLN45272.1 - 0.019 15.0 2.7 0.07 13.2 2.7 1.9 1 0 0 1 1 1 0 KIAA1045 RING finger c-SKI_SMAD_bind PF08782.10 RLN45272.1 - 6.4 7.1 13.1 3 8.1 0.0 3.7 4 0 0 4 4 4 0 c-SKI Smad4 binding domain MatE PF01554.18 RLN45273.1 - 2.4e-25 89.1 2.0 2.9e-25 88.8 2.0 1.1 1 0 0 1 1 1 1 MatE LRR_4 PF12799.7 RLN45277.1 - 0.093 13.2 0.2 4.8 7.7 0.2 2.9 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) DUF1938 PF09153.10 RLN45287.1 - 0.055 13.6 0.1 0.095 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) TraH PF06122.11 RLN45287.1 - 0.068 12.4 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein Na_trans_cytopl PF11933.8 RLN45289.1 - 0.0013 18.6 0.1 0.0028 17.5 0.1 1.5 1 0 0 1 1 1 1 Cytoplasmic domain of voltage-gated Na+ ion channel EF-hand_8 PF13833.6 RLN45289.1 - 0.068 13.0 1.5 9.7 6.1 0.2 3.1 3 0 0 3 3 3 0 EF-hand domain pair OmpH PF03938.14 RLN45289.1 - 8.5 6.7 7.5 1 9.7 3.0 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TAF1_subA PF14929.6 RLN45290.1 - 6.7e-08 32.3 0.1 1.2e-07 31.6 0.1 1.4 1 0 0 1 1 1 1 TAF RNA Polymerase I subunit A STAS_2 PF13466.6 RLN45290.1 - 1.9 8.9 4.7 4.1 7.8 0.2 3.4 4 0 0 4 4 4 0 STAS domain WD40 PF00400.32 RLN45291.1 - 0.00024 21.8 0.1 5.2 8.1 0.1 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat DAPDH_C PF16654.5 RLN45291.1 - 0.062 13.1 0.0 0.078 12.8 0.0 1.1 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain Methyltransf_28 PF02636.17 RLN45292.1 - 4.8e-08 32.9 0.0 4.5e-07 29.8 0.0 2.0 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TPR_1 PF00515.28 RLN45292.1 - 2.1e-05 24.1 1.8 0.007 16.1 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN45292.1 - 2.1e-05 24.3 3.5 0.042 14.0 0.2 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN45292.1 - 0.001 19.3 0.9 1.4 9.3 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN45292.1 - 0.0018 18.3 0.7 0.25 11.6 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Methyltransf_12 PF08242.12 RLN45292.1 - 0.057 14.2 0.0 0.36 11.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain JmjC PF02373.22 RLN45293.1 - 1.9e-14 54.0 0.0 4.3e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 RLN45293.1 - 4.5e-12 46.2 0.1 9.3e-12 45.2 0.1 1.5 1 0 0 1 1 1 1 Cupin-like domain SAM_2 PF07647.17 RLN45293.1 - 1.7e-06 28.0 0.0 3.1e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) APH PF01636.23 RLN45293.1 - 2.2e-06 27.8 0.1 0.0028 17.6 0.1 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family SAM_1 PF00536.30 RLN45293.1 - 3.1e-06 27.5 0.0 6.5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1679 PF07914.11 RLN45293.1 - 0.046 12.6 0.0 0.62 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Cupin_4 PF08007.12 RLN45293.1 - 0.05 13.1 0.2 0.33 10.4 0.1 2.4 1 1 0 2 2 2 0 Cupin superfamily protein Ribosomal_L7Ae PF01248.26 RLN45294.1 - 4.5e-25 87.2 0.5 6.8e-25 86.6 0.2 1.4 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Oxidored_FMN PF00724.20 RLN45307.1 - 5.1e-82 275.9 0.0 7.7e-82 275.3 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Chitin_synth_1 PF01644.17 RLN45307.1 - 4.8e-45 153.5 0.0 7.1e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 RLN45307.1 - 1.7e-24 86.4 0.0 1.2e-21 77.0 0.0 2.7 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 RLN45307.1 - 1e-13 51.7 1.4 4.1e-13 49.7 0.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 MIT PF04212.18 RLN45307.1 - 1.5e-12 47.4 0.1 2.9e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Glyco_tranf_2_3 PF13641.6 RLN45307.1 - 3.3e-11 43.5 0.0 7.3e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Chitin_synth_1N PF08407.11 RLN45307.1 - 5e-10 39.2 0.0 1.5e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Peptidase_C65 PF10275.9 RLN45309.1 - 2.2e-43 148.5 0.0 2.4e-21 76.3 0.0 2.0 1 1 1 2 2 2 2 Peptidase C65 Otubain Peptidase_C101 PF16218.5 RLN45309.1 - 0.018 14.3 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C101 Methyltransf_16 PF10294.9 RLN45311.1 - 9.3e-20 71.1 0.0 4.6e-13 49.3 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase zf-MYND PF01753.18 RLN45311.1 - 8.4e-11 41.8 12.1 2e-10 40.6 12.1 1.7 1 0 0 1 1 1 1 MYND finger Ank_2 PF12796.7 RLN45311.1 - 0.00049 20.6 0.1 0.032 14.8 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Met_10 PF02475.16 RLN45311.1 - 0.0021 17.8 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein zf-C6H2 PF15801.5 RLN45311.1 - 0.0027 18.0 2.6 0.0066 16.7 2.6 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding Ank PF00023.30 RLN45311.1 - 0.0092 16.4 0.0 0.055 13.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Methyltransf_23 PF13489.6 RLN45311.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Smoothelin PF12510.8 RLN45311.1 - 0.013 15.5 3.1 3.9 7.6 0.2 2.8 2 0 0 2 2 2 0 Smoothelin cytoskeleton protein MTS PF05175.14 RLN45311.1 - 0.014 15.0 0.0 0.042 13.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 RLN45311.1 - 0.043 13.2 0.1 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Ank_4 PF13637.6 RLN45311.1 - 0.046 14.3 0.1 1.3 9.7 0.0 3.0 1 1 1 2 2 2 0 Ankyrin repeats (many copies) TFIIE_alpha PF02002.17 RLN45311.1 - 0.062 13.2 0.2 0.36 10.7 0.1 2.3 2 0 0 2 2 2 0 TFIIE alpha subunit Ank_3 PF13606.6 RLN45311.1 - 0.1 13.2 0.0 1.4 9.7 0.0 2.9 2 1 1 3 3 3 0 Ankyrin repeat Hexapep PF00132.24 RLN45313.1 - 8e-21 72.9 20.3 6e-06 25.8 0.7 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 RLN45313.1 - 8.2e-07 28.7 18.6 0.23 11.3 0.9 4.6 2 2 3 5 5 5 5 Hexapeptide repeat of succinyl-transferase Mito_carr PF00153.27 RLN45314.1 - 9.2e-35 118.5 4.6 7.6e-16 57.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Oxidored_FMN PF00724.20 RLN45315.1 - 9.2e-84 281.6 0.0 1e-83 281.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PIP5K PF01504.18 RLN45353.1 - 4.5e-63 213.0 0.0 1e-62 211.9 0.0 1.5 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase COesterase PF00135.28 RLN45353.1 - 3.8e-43 148.1 0.0 5.6e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Sulfate_transp PF00916.20 RLN45354.1 - 8.2e-76 255.2 19.6 1.4e-39 135.9 0.5 2.3 2 0 0 2 2 2 2 Sulfate permease family STAS PF01740.21 RLN45354.1 - 1e-07 31.6 0.2 1.8e-07 30.8 0.2 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 RLN45354.1 - 0.014 15.7 0.1 0.043 14.2 0.1 1.7 1 0 0 1 1 1 0 STAS domain MFS_MOT1 PF16983.5 RLN45354.1 - 0.023 15.1 15.9 0.049 14.0 4.7 3.3 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily DUF986 PF06173.12 RLN45354.1 - 0.11 12.6 0.3 0.3 11.2 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF986) CDP-OH_P_transf PF01066.21 RLN45354.1 - 0.73 10.6 0.0 0.73 10.6 0.0 3.1 2 2 0 2 2 2 0 CDP-alcohol phosphatidyltransferase Pro_isomerase PF00160.21 RLN45355.1 - 3.7e-41 141.0 0.0 6.4e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ApoLp-III PF07464.11 RLN45438.1 - 0.08 13.0 2.0 0.19 11.8 1.7 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) SoDot-IcmSS PF16848.5 RLN45438.1 - 0.42 10.6 3.0 2.1 8.3 0.4 2.1 1 1 1 2 2 2 0 Substrate of the Dot/Icm secretion system, putative DUF896 PF05979.12 RLN45439.1 - 0.19 11.6 0.5 0.38 10.7 0.5 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) adh_short PF00106.25 RLN45440.1 - 5e-43 146.8 0.0 7.1e-43 146.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN45440.1 - 2.6e-27 95.9 0.0 4.2e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN45440.1 - 2.4e-10 40.6 0.2 7.5e-10 39.0 0.2 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN45440.1 - 0.019 14.4 0.1 0.056 12.9 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 RLN45440.1 - 0.032 14.0 0.4 0.11 12.3 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.19 RLN45440.1 - 0.041 13.3 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 RLN45440.1 - 0.069 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 RLN45440.1 - 0.13 12.7 0.1 0.23 11.9 0.1 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Ribosomal_L27A PF00828.19 RLN45441.1 - 1.2e-39 136.0 1.5 1.8e-39 135.3 1.5 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A PhoD PF09423.10 RLN45441.1 - 0.18 10.8 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 PhoD-like phosphatase PMI_typeI PF01238.21 RLN45442.1 - 9.7e-98 327.8 0.0 1.2e-97 327.5 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Pkinase PF00069.25 RLN45443.1 - 4.5e-61 206.5 0.0 6.8e-61 205.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN45443.1 - 1.2e-44 152.5 0.0 1.7e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN45443.1 - 6.6e-06 25.6 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RLN45443.1 - 2.8e-05 23.1 0.0 4.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN45443.1 - 0.044 13.7 0.3 2.2 8.1 0.1 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN45443.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAP2 PF01569.21 RLN45444.1 - 2.6e-08 33.7 2.4 2.6e-08 33.7 2.4 2.2 1 1 1 2 2 2 1 PAP2 superfamily Transmemb_17 PF09799.9 RLN45444.1 - 4.9 7.8 7.9 0.23 12.1 1.6 2.1 2 0 0 2 2 2 0 Predicted membrane protein UbiA PF01040.18 RLN45444.1 - 6.4 6.0 12.0 0.15 11.3 1.2 2.5 3 0 0 3 3 3 0 UbiA prenyltransferase family PAP2 PF01569.21 RLN45445.1 - 1.1e-06 28.5 3.1 1.1e-06 28.5 3.1 2.0 1 1 1 2 2 2 1 PAP2 superfamily Agenet PF05641.12 RLN45445.1 - 0.00021 21.7 0.0 0.00048 20.5 0.0 1.6 1 0 0 1 1 1 1 Agenet domain DUF212 PF02681.14 RLN45445.1 - 0.078 13.1 1.6 0.36 11.0 0.6 2.1 1 1 1 2 2 2 0 Divergent PAP2 family CDC45 PF02724.14 RLN45445.1 - 3.2 5.9 6.2 4.3 5.5 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2070 PF09843.9 RLN45445.1 - 5.4 5.2 6.3 8.5 4.5 6.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) AhpC-TSA PF00578.21 RLN45446.1 - 1.1e-24 86.7 0.0 1.4e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RLN45446.1 - 4.8e-12 45.8 0.0 6.6e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 RLN45446.1 - 4.1e-11 42.5 0.2 6.7e-11 41.9 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 RLN45446.1 - 0.022 14.9 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme DUF3966 PF13110.6 RLN45446.1 - 0.21 11.5 0.2 0.37 10.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) ADK PF00406.22 RLN45447.1 - 2.9e-28 98.9 0.0 5.6e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 RLN45447.1 - 1.3e-16 61.2 0.0 4.3e-16 59.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 RLN45447.1 - 9.7e-08 32.3 1.5 2.9e-07 30.8 0.1 2.5 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 RLN45447.1 - 6.7e-06 26.7 0.1 2.4e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RLN45447.1 - 8e-05 23.1 0.0 0.00016 22.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 RLN45447.1 - 0.0005 19.9 0.1 0.0017 18.1 0.0 2.0 2 0 0 2 2 2 1 Cytidylate kinase Rad17 PF03215.15 RLN45447.1 - 0.0022 17.9 0.0 0.3 11.0 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 RLN45447.1 - 0.0054 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 RLN45447.1 - 0.0081 16.1 0.0 0.032 14.1 0.0 2.1 2 0 0 2 2 2 1 NACHT domain Thymidylate_kin PF02223.17 RLN45447.1 - 0.0094 15.6 1.4 3.5 7.2 0.0 3.6 3 1 0 3 3 3 1 Thymidylate kinase ABC_tran PF00005.27 RLN45447.1 - 0.0097 16.4 0.0 0.041 14.4 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_28 PF13521.6 RLN45447.1 - 0.013 15.8 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RLN45447.1 - 0.013 15.9 0.2 0.033 14.6 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 RLN45447.1 - 0.014 15.8 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Hydin_ADK PF17213.3 RLN45447.1 - 0.021 15.1 3.9 0.17 12.1 0.0 2.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_22 PF13401.6 RLN45447.1 - 0.026 14.8 0.0 0.071 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 RLN45447.1 - 0.03 14.3 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 RLN45447.1 - 0.033 13.9 0.0 0.083 12.6 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 RLN45447.1 - 0.059 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 NTPase DUF3987 PF13148.6 RLN45447.1 - 0.082 11.9 0.1 5.1 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) dNK PF01712.19 RLN45447.1 - 0.13 12.1 0.3 0.3 10.9 0.0 1.7 2 0 0 2 2 2 0 Deoxynucleoside kinase Macoilin PF09726.9 RLN45447.1 - 0.17 10.4 0.8 0.26 9.8 0.8 1.3 1 0 0 1 1 1 0 Macoilin family cobW PF02492.19 RLN45447.1 - 0.18 11.3 0.1 0.51 9.9 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Complex1_LYR PF05347.15 RLN45448.1 - 5.3e-14 52.0 0.3 7.3e-14 51.6 0.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) zf-ribbon_3 PF13248.6 RLN45448.1 - 1.9e-05 23.9 4.3 1.9e-05 23.9 4.3 1.9 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.7 RLN45448.1 - 0.00012 22.0 0.8 0.00012 22.0 0.8 1.6 2 0 0 2 2 2 1 Double zinc ribbon Complex1_LYR_2 PF13233.6 RLN45448.1 - 0.00026 21.6 0.3 0.00033 21.3 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 RLN45448.1 - 0.0003 21.3 0.7 0.0019 18.8 0.7 2.0 1 1 0 1 1 1 1 Complex1_LYR-like zinc_ribbon_2 PF13240.6 RLN45448.1 - 0.00077 19.1 5.5 0.00077 19.1 5.5 1.6 2 0 0 2 2 2 1 zinc-ribbon domain NOB1_Zn_bind PF08772.11 RLN45448.1 - 0.0071 16.5 2.6 0.014 15.6 2.0 1.7 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_15 PF17032.5 RLN45448.1 - 0.015 16.1 0.2 0.015 16.1 0.2 1.5 2 0 0 2 2 1 0 zinc-ribbon family HypA PF01155.19 RLN45448.1 - 0.017 15.2 0.2 0.024 14.7 0.2 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cript PF10235.9 RLN45448.1 - 0.018 15.6 0.4 0.018 15.6 0.4 1.6 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT DUF3486 PF11985.8 RLN45448.1 - 0.063 13.7 0.1 0.083 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) Nudix_N_2 PF14803.6 RLN45448.1 - 0.22 11.5 3.4 1.6 8.7 0.4 2.6 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_4 PF13717.6 RLN45448.1 - 0.34 10.9 5.2 0.65 10.0 0.5 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 RLN45448.1 - 0.47 10.2 9.7 0.99 9.1 0.6 3.0 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain UPF0547 PF10571.9 RLN45448.1 - 2.5 8.3 8.8 2.8 8.1 5.3 2.4 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 Peptidase_S26 PF10502.9 RLN45449.1 - 0.001 18.9 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 UL41A PF17591.2 RLN45449.1 - 0.11 12.7 0.8 0.33 11.1 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus UL41A CLP_protease PF00574.23 RLN45450.1 - 8.4e-70 234.4 0.0 1.2e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 Clp protease zf-HIT PF04438.16 RLN45450.1 - 7.1e-09 35.4 14.8 1.1e-08 34.8 14.8 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 RLN45450.1 - 0.29 11.3 15.8 0.52 10.4 15.8 1.4 1 0 0 1 1 1 0 MYND finger p450 PF00067.22 RLN45452.1 - 1.8e-18 66.5 0.0 2.3e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 C12orf66_like PF09404.10 RLN45452.1 - 0.11 11.3 0.0 3.6 6.3 0.0 2.1 2 0 0 2 2 2 0 KICSTOR complex C12orf66 like p450 PF00067.22 RLN45453.1 - 2.3e-69 234.4 0.0 3e-69 234.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SCP2_2 PF13530.6 RLN45453.1 - 0.0061 16.9 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 Sterol carrier protein domain Methyltransf_11 PF08241.12 RLN45516.1 - 5.5e-17 62.2 0.0 2.2e-16 60.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN45516.1 - 3.3e-16 59.4 0.0 7.1e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN45516.1 - 3.6e-14 53.2 0.1 1.8e-13 51.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN45516.1 - 2.3e-11 43.8 0.1 6.3e-11 42.4 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN45516.1 - 3e-07 31.1 0.0 1.6e-06 28.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN45516.1 - 0.00041 19.7 0.0 0.00095 18.6 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 RLN45516.1 - 0.0025 17.2 0.0 0.0043 16.5 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.12 RLN45516.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW AdoMet_MTase PF07757.13 RLN45516.1 - 0.013 15.9 0.0 0.037 14.3 0.0 1.8 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 RLN45516.1 - 0.013 15.5 0.1 0.045 13.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain WD40 PF00400.32 RLN45517.1 - 3.8e-10 40.2 0.4 0.046 14.6 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN45517.1 - 9.9e-08 32.2 0.0 0.009 16.3 0.0 3.8 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 RLN45517.1 - 0.031 13.8 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 PQQ-like domain PD40 PF07676.12 RLN45517.1 - 0.17 11.9 0.0 0.82 9.7 0.0 2.1 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Glyco_hydr_30_2 PF14587.6 RLN45518.1 - 7e-21 75.2 1.5 1.7e-20 74.0 1.5 1.6 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.15 RLN45518.1 - 1.6e-11 44.0 0.1 2.4e-11 43.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Retrotrans_gag PF03732.17 RLN45521.1 - 6.9e-07 29.5 0.1 1.3e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein PNMA PF14893.6 RLN45521.1 - 0.039 13.4 0.0 0.085 12.2 0.0 1.5 1 0 0 1 1 1 0 PNMA PEPCK_ATP PF01293.20 RLN45559.1 - 1.3e-12 47.2 0.0 1.5e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase HAD_2 PF13419.6 RLN45560.1 - 6.3e-08 32.9 0.0 6.8e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RLN45560.1 - 0.00035 20.6 0.0 0.00057 19.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 RLN45560.1 - 0.013 15.8 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF4261 PF14080.6 RLN45560.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4261) E1_dh PF00676.20 RLN45562.1 - 2.1e-61 207.5 0.1 9.3e-54 182.4 0.1 2.1 1 1 1 2 2 2 2 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 RLN45562.1 - 0.0001 22.1 0.0 0.0018 18.1 0.0 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 RLN45562.1 - 0.011 15.0 0.0 0.045 13.0 0.0 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.10 RLN45562.1 - 0.053 12.3 0.0 0.07 11.9 0.0 1.1 1 0 0 1 1 1 0 XFP N-terminal domain DUF2423 PF10338.9 RLN45563.1 - 5.1e-10 39.4 2.1 5.1e-10 39.4 2.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) ADH_zinc_N PF00107.26 RLN45563.1 - 0.059 13.3 0.6 0.21 11.6 0.3 1.9 1 1 1 2 2 2 0 Zinc-binding dehydrogenase Laps PF10169.9 RLN45563.1 - 4.4 7.9 12.7 24 5.5 12.7 2.1 1 1 0 1 1 1 0 Learning-associated protein GYF_2 PF14237.6 RLN45564.1 - 8.5e-24 83.1 0.7 3.5e-13 49.1 0.1 2.8 2 0 0 2 2 2 2 GYF domain 2 RRM_1 PF00076.22 RLN45564.1 - 1.2e-11 44.2 0.1 2.6e-06 27.1 0.1 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RLN45564.1 - 0.00057 19.7 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 RLN45564.1 - 0.0026 17.7 0.0 0.13 12.3 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 RLN45564.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif RRM_5 PF13893.6 RLN45564.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med19 PF10278.9 RLN45564.1 - 0.85 9.5 8.9 1.1 9.2 5.4 2.4 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Herpes_DNAp_acc PF04929.12 RLN45564.1 - 1.1 8.2 7.3 1.2 8.0 4.9 2.1 2 1 0 2 2 2 0 Herpes DNA replication accessory factor Vpu PF00558.19 RLN45564.1 - 1.8 8.4 12.0 3.1 7.6 0.8 3.4 3 0 0 3 3 3 0 Vpu protein MoaE PF02391.17 RLN45565.1 - 2.6e-40 137.2 0.1 4.3e-40 136.5 0.1 1.3 1 0 0 1 1 1 1 MoaE protein CEP19 PF14933.6 RLN45565.1 - 3.9e-17 63.1 0.7 3.3e-16 60.0 0.7 2.0 1 1 0 1 1 1 1 CEP19-like protein Coilin_N PF15862.5 RLN45566.1 - 2.8e-16 59.6 0.0 4.9e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Coilin N-terminus Dehydrin PF00257.19 RLN45566.1 - 0.022 15.3 1.5 0.055 14.0 1.5 1.7 1 0 0 1 1 1 0 Dehydrin Malate_synthase PF01274.22 RLN45567.1 - 1e-63 215.4 0.0 1.9e-59 201.4 0.0 2.1 1 1 1 2 2 2 2 Malate synthase DUF3047 PF11249.8 RLN45567.1 - 0.3 10.5 1.2 3 7.3 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3047) SNF2_N PF00176.23 RLN45568.1 - 2.4e-64 217.3 0.0 3.9e-64 216.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN45568.1 - 2.2e-19 69.9 0.0 1.2e-18 67.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 RLN45568.1 - 2.2e-09 36.9 0.0 4.3e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 RLN45568.1 - 3.9e-08 33.5 0.1 2.1e-07 31.1 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RNA_pol_Rpa2_4 PF06883.12 RLN45568.1 - 0.12 12.4 0.4 2.1 8.4 0.0 3.0 2 0 0 2 2 2 0 RNA polymerase I, Rpa2 specific domain NYD-SP28_assoc PF14775.6 RLN45569.1 - 6.5 6.9 7.1 38 4.5 0.0 3.4 3 1 0 3 3 3 0 Sperm tail C-terminal domain DinB_2 PF12867.7 RLN45570.1 - 0.064 13.8 0.2 0.2 12.2 0.2 1.9 1 0 0 1 1 1 0 DinB superfamily Pkinase_Tyr PF07714.17 RLN45571.1 - 7.3e-94 313.9 0.0 2.5e-46 158.1 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 RLN45571.1 - 1.7e-83 280.0 0.0 6.3e-42 143.8 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain PH PF00169.29 RLN45571.1 - 3.1e-16 59.8 1.5 7.2e-07 29.7 0.3 4.5 4 1 0 4 4 4 3 PH domain RIO1 PF01163.22 RLN45571.1 - 1.3e-05 24.9 0.0 0.2 11.2 0.0 2.4 2 0 0 2 2 2 2 RIO1 family Kinase-like PF14531.6 RLN45571.1 - 1.5e-05 24.5 0.0 0.046 13.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 RLN45571.1 - 4.4e-05 22.5 0.0 0.022 13.5 0.0 2.6 3 0 0 3 3 3 2 Fungal protein kinase APH PF01636.23 RLN45571.1 - 6.4e-05 23.0 0.7 0.39 10.6 0.1 2.9 2 0 0 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN45571.1 - 0.0032 16.5 0.0 1.6 7.6 0.0 2.2 2 0 0 2 2 2 2 Haspin like kinase domain Kdo PF06293.14 RLN45571.1 - 0.0083 15.5 0.2 2.9 7.2 0.1 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 RLN45571.1 - 0.018 14.1 0.8 0.15 11.0 0.3 2.3 2 0 0 2 2 2 0 Seadornavirus VP7 PH_8 PF15409.6 RLN45571.1 - 0.028 14.7 0.6 0.17 12.2 0.2 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain CHORD PF04968.12 RLN45573.1 - 0.00015 22.4 3.7 0.00032 21.4 3.7 1.5 1 0 0 1 1 1 1 CHORD KIAA1430 PF13879.6 RLN45573.1 - 0.013 16.2 4.6 0.013 16.2 4.6 3.5 2 2 1 3 3 3 0 KIAA1430 homologue TPR_MLP1_2 PF07926.12 RLN45573.1 - 0.014 15.4 2.9 0.014 15.4 2.9 6.1 2 2 4 6 6 6 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 RLN45573.1 - 0.018 15.2 5.7 0.018 15.2 5.7 3.4 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) BTK PF00779.19 RLN45573.1 - 0.033 14.0 1.0 0.083 12.7 1.0 1.7 1 0 0 1 1 1 0 BTK motif SlyX PF04102.12 RLN45573.1 - 0.14 12.7 29.5 0.073 13.7 5.1 4.9 2 2 3 5 5 5 0 SlyX Mito_carr PF00153.27 RLN45597.1 - 3.1e-62 206.5 2.6 2.1e-22 78.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DsrD PF08679.11 RLN45597.1 - 0.18 12.1 0.0 8.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) BT1 PF03092.16 RLN45598.1 - 1.9e-18 66.0 13.2 8e-14 50.8 0.9 3.3 3 0 0 3 3 3 3 BT1 family DUF5353 PF17304.2 RLN45598.1 - 2.5 7.9 7.7 0.27 11.0 2.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5353) BT1 PF03092.16 RLN45599.1 - 1.4e-14 53.3 12.8 4.4e-11 41.7 0.8 3.2 3 0 0 3 3 3 3 BT1 family MFS_1 PF07690.16 RLN45599.1 - 0.0027 16.7 25.4 0.019 13.9 24.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily SmpA_OmlA PF04355.13 RLN45599.1 - 0.087 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 SmpA / OmlA family CRPA PF05745.11 RLN45599.1 - 2.5 8.1 4.7 13 5.8 1.7 2.5 2 1 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) BT1 PF03092.16 RLN45600.1 - 2.4e-16 59.1 17.4 4.2e-13 48.4 1.1 3.3 3 0 0 3 3 3 3 BT1 family PUCC PF03209.15 RLN45600.1 - 0.00051 19.2 0.2 0.00051 19.2 0.2 2.9 3 1 0 3 3 3 1 PUCC protein BT1 PF03092.16 RLN45601.1 - 9e-19 67.1 9.1 2e-17 62.6 3.0 2.3 2 0 0 2 2 2 2 BT1 family Pkinase_Tyr PF07714.17 RLN45704.1 - 0.047 13.0 0.1 0.078 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Mif2_N PF15624.6 RLN45704.1 - 0.067 13.9 8.6 0.31 11.8 8.3 1.8 1 1 1 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Pkinase PF00069.25 RLN45704.1 - 0.16 11.3 0.2 0.24 10.8 0.2 1.2 1 0 0 1 1 1 0 Protein kinase domain EF-hand_1 PF00036.32 RLN45705.1 - 3.1e-19 67.0 7.8 8.6e-06 24.9 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 RLN45705.1 - 6.7e-18 64.9 6.0 1.6e-11 44.4 0.2 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN45705.1 - 1.6e-14 52.6 11.4 9e-05 21.8 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 RLN45705.1 - 2.6e-14 51.8 7.7 0.00053 19.7 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 RLN45705.1 - 2.5e-09 36.8 9.8 0.00099 18.9 0.5 3.4 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RLN45705.1 - 0.00023 21.5 0.9 0.13 12.6 0.2 2.6 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RLN45705.1 - 0.032 14.2 5.9 2 8.4 0.1 3.2 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 RLN45705.1 - 0.089 13.1 0.3 0.86 10.0 0.1 2.5 2 1 0 2 2 2 0 EF-hand domain EF-hand_14 PF17959.1 RLN45705.1 - 0.15 12.5 0.6 12 6.3 0.1 2.8 2 1 0 2 2 2 0 EF-hand domain DAP3 PF10236.9 RLN45706.1 - 6.8e-33 114.2 0.0 2e-32 112.6 0.0 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 RLN45706.1 - 0.0017 18.7 0.1 0.0065 16.9 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.7 RLN45706.1 - 0.11 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DUF2791 PF10923.8 RLN45706.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) VRR_NUC PF08774.11 RLN45707.1 - 0.046 13.8 0.0 0.068 13.2 0.0 1.2 1 0 0 1 1 1 0 VRR-NUC domain SNF2_N PF00176.23 RLN45708.1 - 3.2e-73 246.4 0.2 8.5e-73 245.1 0.2 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN45708.1 - 4.9e-18 65.5 0.0 1.5e-17 63.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 RLN45708.1 - 7.5e-16 58.0 0.0 2.1e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.6 RLN45708.1 - 1.1e-13 51.6 1.0 1.1e-13 51.6 1.0 4.1 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.13 RLN45708.1 - 1.2e-11 44.8 5.4 1.2e-11 44.8 5.4 4.8 5 0 0 5 5 5 1 HSA ResIII PF04851.15 RLN45708.1 - 6.6e-10 39.2 2.9 1.9e-09 37.7 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RLN45708.1 - 1.5e-06 28.1 0.1 6.9e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1682 PF07946.14 RLN45708.1 - 0.0014 17.9 2.4 0.0014 17.9 2.4 3.0 4 0 0 4 4 4 1 Protein of unknown function (DUF1682) HDA2-3 PF11496.8 RLN45708.1 - 0.0027 16.9 0.0 0.035 13.3 0.0 2.8 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Epimerase PF01370.21 RLN45737.1 - 9.6e-29 100.5 0.0 1.4e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RLN45737.1 - 2e-20 73.5 0.5 1.4e-19 70.7 0.5 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 RLN45737.1 - 3.9e-13 49.1 0.0 5.4e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RLN45737.1 - 1.4e-11 44.1 1.2 6.3e-10 38.7 1.2 2.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 RLN45737.1 - 1e-10 41.1 0.0 1.5e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 RLN45737.1 - 3.1e-07 29.9 0.2 1.2e-06 27.9 0.0 2.0 2 1 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 RLN45737.1 - 0.00056 19.9 0.0 0.00078 19.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 RLN45737.1 - 0.0088 15.6 0.0 0.53 9.8 0.1 2.3 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 RLN45737.1 - 0.016 15.1 0.7 0.15 11.9 0.7 2.1 1 1 0 1 1 1 0 KR domain Actin PF00022.19 RLN45739.1 - 2.9e-09 36.1 0.0 3.3e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 Actin Ge1_WD40 PF16529.5 RLN45745.1 - 4.2e-14 52.3 0.0 2e-07 30.3 0.0 2.2 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 RLN45745.1 - 1.9e-05 25.3 0.4 0.12 13.3 0.1 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat CelTOS PF18659.1 RLN45745.1 - 0.16 12.4 0.2 36 4.8 0.0 3.5 3 1 0 3 3 3 0 Cell-traversal protein for ookinetes and sporozoites Mer2 PF09074.10 RLN45745.1 - 0.2 11.4 4.7 0.69 9.7 4.6 2.0 1 1 0 1 1 1 0 Mer2 LPP PF04728.13 RLN45745.1 - 0.22 11.9 0.6 0.93 9.9 0.6 2.1 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Spore_III_AB PF09548.10 RLN45745.1 - 2.9 8.0 4.0 4.2 7.5 0.1 2.7 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) MoCF_biosynth PF00994.24 RLN45746.1 - 3.2e-15 56.0 0.0 5.2e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain HTH_ABP1_N PF18107.1 RLN45762.1 - 2.2e-07 30.5 0.4 2.2e-07 30.5 0.4 2.0 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 RLN45762.1 - 3.6e-07 30.1 0.4 2.7e-06 27.3 0.1 2.5 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain WDCP PF15390.6 RLN45762.1 - 0.081 11.3 9.2 0.15 10.4 9.2 1.4 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family TMEM247 PF15444.6 RLN45762.1 - 0.12 12.4 5.1 0.49 10.4 5.1 2.0 2 0 0 2 2 2 0 Transmembrane protein 247 Atg14 PF10186.9 RLN45762.1 - 1.1 8.3 17.7 2.2 7.3 17.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ABC_tran PF00005.27 RLN45763.1 - 4.6e-12 46.6 0.0 7.6e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN45763.1 - 1.8e-06 28.0 0.0 2.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 RLN45763.1 - 0.017 15.4 0.0 0.19 12.0 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 RLN45763.1 - 0.069 12.9 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain HTH_ABP1_N PF18107.1 RLN45764.1 - 3.4e-08 33.1 0.4 1.1e-07 31.4 0.4 1.9 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 RLN45764.1 - 8.6e-08 32.1 0.3 1.2e-06 28.4 0.0 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain HTH_32 PF13565.6 RLN45764.1 - 0.045 14.4 0.4 0.045 14.4 0.4 3.7 4 0 0 4 4 4 0 Homeodomain-like domain TMEM247 PF15444.6 RLN45764.1 - 0.97 9.4 5.9 3.1 7.8 5.9 1.8 1 0 0 1 1 1 0 Transmembrane protein 247 TMPIT PF07851.13 RLN45764.1 - 5.6 6.1 6.8 1.6 7.9 3.2 1.7 2 0 0 2 2 2 0 TMPIT-like protein HTH_ABP1_N PF18107.1 RLN45765.1 - 1e-07 31.5 0.0 1e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 RLN45765.1 - 5.2e-07 29.6 0.2 2.7e-06 27.3 0.1 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_33 PF13592.6 RLN45765.1 - 0.0033 17.0 0.0 0.013 15.1 0.0 2.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.6 RLN45765.1 - 0.062 13.9 0.1 0.062 13.9 0.1 4.9 4 1 0 4 4 4 0 Homeodomain-like domain WDCP PF15390.6 RLN45765.1 - 0.11 10.8 9.7 0.22 9.9 9.7 1.4 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family TMEM247 PF15444.6 RLN45765.1 - 0.26 11.3 5.5 0.63 10.0 5.5 1.6 1 0 0 1 1 1 0 Transmembrane protein 247 Atg14 PF10186.9 RLN45765.1 - 2.4 7.1 18.9 3.8 6.5 18.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ank_2 PF12796.7 RLN45766.1 - 4e-39 133.1 3.5 1.6e-08 35.0 0.0 7.8 6 2 0 8 8 8 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN45766.1 - 4.9e-25 87.6 17.2 5.5e-05 23.6 0.5 10.4 7 4 4 11 11 11 8 Ankyrin repeats (many copies) Ank PF00023.30 RLN45766.1 - 3.5e-19 68.3 10.7 0.0013 19.1 0.0 9.6 9 0 0 9 9 9 4 Ankyrin repeat Ank_3 PF13606.6 RLN45766.1 - 4.5e-19 66.5 15.3 0.061 13.9 0.0 12.4 12 0 0 12 12 12 5 Ankyrin repeat Ank_5 PF13857.6 RLN45766.1 - 6.3e-16 58.2 8.1 0.0074 16.6 0.0 8.3 5 3 3 8 8 8 6 Ankyrin repeats (many copies) DUF4034 PF13226.6 RLN45767.1 - 0.02 14.2 0.2 0.073 12.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4034) Ras PF00071.22 RLN45768.1 - 7.3e-19 67.9 0.0 1.2e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN45768.1 - 2.6e-07 30.9 0.0 7e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AA_kinase PF00696.28 RLN45769.1 - 1.6e-31 109.8 0.2 2e-31 109.4 0.2 1.1 1 0 0 1 1 1 1 Amino acid kinase family Lac_bphage_repr PF06543.12 RLN45769.1 - 0.022 14.7 1.7 5 7.2 0.5 2.5 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor UCR_TM PF02921.14 RLN45770.1 - 3.8e-14 52.9 0.6 8.4e-14 51.8 0.6 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 RLN45770.1 - 9.6e-13 47.9 0.0 2.1e-12 46.8 0.0 1.6 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Mrx7 PF10906.8 RLN45771.1 - 0.0072 16.6 0.1 0.012 15.9 0.1 1.3 1 0 0 1 1 1 1 MIOREX complex component 7 Aldo_ket_red PF00248.21 RLN45773.1 - 5.8e-11 42.1 0.1 6.3e-11 42.0 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase_Tyr PF07714.17 RLN45789.1 - 6.5e-27 94.4 0.0 3.1e-20 72.5 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 RLN45789.1 - 4e-25 88.7 0.0 1.1e-13 51.2 0.0 3.3 2 2 0 2 2 2 2 Protein kinase domain LRR_8 PF13855.6 RLN45789.1 - 4.5e-15 55.2 0.4 1.7e-05 24.5 0.1 3.8 2 1 1 3 3 3 3 Leucine rich repeat LRR_5 PF13306.6 RLN45789.1 - 2.7e-06 27.4 0.3 2.3e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 RLN45789.1 - 0.00075 19.8 0.2 0.16 12.4 0.0 3.9 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) BTAD PF03704.17 RLN45789.1 - 0.044 14.2 0.1 2.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial transcriptional activator domain Ephrin_rec_like PF07699.13 RLN45789.1 - 0.15 11.8 5.4 0.26 11.1 2.5 2.6 1 1 0 1 1 1 0 Putative ephrin-receptor like WD40 PF00400.32 RLN45790.1 - 3e-23 81.7 15.0 2.6e-05 24.9 0.1 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN45790.1 - 1e-07 32.1 1.5 0.0032 17.7 0.7 2.9 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN45790.1 - 0.0086 14.8 4.2 0.055 12.1 0.5 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PAS_4 PF08448.10 RLN45791.1 - 0.08 13.2 0.5 0.62 10.3 0.1 2.2 1 1 1 2 2 2 0 PAS fold FUSC PF04632.12 RLN45791.1 - 0.32 9.5 2.2 0.34 9.4 2.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4750 PF15938.5 RLN45792.1 - 1.6e-20 72.5 1.6 2.5e-20 71.9 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4750) IFRD_C PF04836.12 RLN45792.1 - 0.14 12.7 2.7 0.62 10.7 0.0 2.4 2 0 0 2 2 2 0 Interferon-related protein conserved region DUF2798 PF11391.8 RLN45792.1 - 1 9.5 10.4 0.92 9.6 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) dsrm PF00035.26 RLN45827.1 - 2.3e-05 25.0 0.0 4.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif GatB_Yqey PF02637.18 RLN45827.1 - 0.15 11.9 0.1 0.43 10.4 0.0 1.7 2 0 0 2 2 2 0 GatB domain PH PF00169.29 RLN45828.1 - 0.0027 18.2 0.0 0.0084 16.6 0.0 1.8 2 0 0 2 2 2 1 PH domain AAA PF00004.29 RLN45829.1 - 2e-40 138.3 0.0 3.7e-40 137.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RLN45829.1 - 5.1e-10 39.0 0.4 1.1e-09 38.0 0.4 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 RLN45829.1 - 9.1e-10 38.4 0.1 2e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 RLN45829.1 - 2.7e-06 27.7 0.2 0.0045 17.3 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 RLN45829.1 - 5.1e-06 26.7 0.0 1.5e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 RLN45829.1 - 3.3e-05 23.2 0.0 5.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 RLN45829.1 - 7.8e-05 22.7 0.1 0.00048 20.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RLN45829.1 - 0.00017 22.0 0.3 0.0023 18.4 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 RLN45829.1 - 0.0017 18.1 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 RLN45829.1 - 0.012 14.9 0.1 0.24 10.7 0.1 2.3 1 1 0 2 2 2 0 KaiC RNA_helicase PF00910.22 RLN45829.1 - 0.014 15.8 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 RLN45829.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 RLN45829.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 RLN45829.1 - 0.02 14.8 0.0 0.06 13.2 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 RLN45829.1 - 0.041 13.6 0.2 0.12 12.0 0.2 2.0 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 RLN45829.1 - 0.052 13.3 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 RLN45829.1 - 0.054 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 RLN45829.1 - 0.096 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 RLN45829.1 - 0.098 12.6 0.2 0.25 11.3 0.1 1.7 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 RLN45829.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 RLN45829.1 - 0.11 12.7 0.1 0.27 11.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 RLN45829.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 RLN45829.1 - 0.12 11.8 0.1 0.29 10.5 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Prot_ATP_OB_N PF17758.1 RLN45829.1 - 0.14 11.8 1.7 0.23 11.1 0.1 2.2 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_25 PF13481.6 RLN45829.1 - 0.16 11.6 0.4 0.88 9.1 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 RLN45829.1 - 0.18 11.3 0.1 0.44 10.0 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Pkinase PF00069.25 RLN45830.1 - 1.5e-70 237.6 0.0 1.8e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN45830.1 - 1.7e-33 116.0 0.0 2.3e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN45830.1 - 0.005 16.2 0.3 0.012 15.0 0.3 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 RLN45830.1 - 0.013 15.1 0.4 0.52 9.9 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 RLN45830.1 - 0.023 14.0 0.1 0.34 10.2 0.0 2.1 1 1 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 RLN45830.1 - 0.061 12.3 0.1 0.096 11.6 0.1 1.3 1 1 0 1 1 1 0 Haspin like kinase domain YukC PF10140.9 RLN45830.1 - 0.11 11.4 0.0 0.34 9.7 0.0 1.7 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC Diphthamide_syn PF01866.17 RLN45831.1 - 2.4e-29 102.7 0.0 6.6e-25 88.2 0.0 2.0 1 1 1 2 2 2 2 Putative diphthamide synthesis protein Diphthamide_syn PF01866.17 RLN45832.1 - 8.8e-34 117.3 1.4 1.1e-33 117.1 1.4 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein CoA_binding_2 PF13380.6 RLN45833.1 - 0.019 15.5 0.0 9.2 6.8 0.0 2.5 2 0 0 2 2 2 0 CoA binding domain bZIP_1 PF00170.21 RLN45833.1 - 0.021 14.9 4.4 0.021 14.9 4.4 2.5 2 0 0 2 2 2 0 bZIP transcription factor Pkip-1 PF06878.11 RLN45833.1 - 0.36 10.9 4.2 3.2 7.8 4.2 2.1 1 1 0 1 1 1 0 Pkip-1 protein SWIRM-assoc_2 PF16496.5 RLN45833.1 - 0.63 8.9 9.5 1.1 8.1 9.5 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Ribosomal_L1 PF00687.21 RLN45834.1 - 9.8e-50 169.1 0.0 1.1e-49 169.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family zf-RanBP PF00641.18 RLN45835.1 - 5.7e-12 44.7 19.1 1.8e-06 27.2 8.9 2.2 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-P11 PF03854.14 RLN45835.1 - 0.13 12.0 1.6 1.6 8.5 0.1 2.2 2 0 0 2 2 2 0 P-11 zinc finger DUF35_N PF12172.8 RLN45835.1 - 0.27 11.1 6.6 0.2 11.6 0.5 2.4 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) TackOD1 PF18551.1 RLN45835.1 - 0.66 9.6 4.9 8.4 6.0 0.9 2.4 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 ER-remodelling PF14755.6 RLN45836.1 - 0.0034 17.7 13.2 0.099 12.9 0.9 2.2 2 0 0 2 2 2 2 Intracellular membrane remodeller CENP-Q PF13094.6 RLN45836.1 - 0.54 10.4 7.4 0.22 11.7 3.2 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Zip PF02535.22 RLN45837.1 - 6.1e-47 160.5 16.0 1.3e-46 159.4 16.0 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter Acetyltransf_6 PF13480.7 RLN45838.1 - 0.53 10.4 2.9 0.33 11.1 0.6 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AAA PF00004.29 RLN45839.1 - 1.3e-36 125.9 0.0 2.7e-36 124.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 RLN45839.1 - 1.2e-06 28.4 0.1 3.9e-06 26.8 0.1 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 RLN45839.1 - 2.7e-05 24.3 0.0 4.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 RLN45839.1 - 0.0001 22.3 0.0 0.00048 20.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RLN45839.1 - 0.00024 20.9 0.0 0.00046 20.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RLN45839.1 - 0.00036 20.7 1.9 0.0057 16.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_lid_3 PF17862.1 RLN45839.1 - 0.00053 19.7 0.3 0.031 14.1 0.0 3.2 3 0 0 3 3 3 1 AAA+ lid domain Mg_chelatase PF01078.21 RLN45839.1 - 0.0018 17.7 0.0 0.0046 16.4 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 RLN45839.1 - 0.0033 17.2 0.0 0.0088 15.8 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 RLN45839.1 - 0.0055 17.1 0.8 0.024 15.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RLN45839.1 - 0.0086 16.3 0.3 0.095 13.0 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RLN45839.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 RLN45839.1 - 0.018 14.2 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.13 RLN45839.1 - 0.035 13.3 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 RLN45839.1 - 0.043 14.2 0.0 0.14 12.5 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 RLN45839.1 - 0.045 12.8 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 RLN45839.1 - 0.046 13.7 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 RLN45839.1 - 0.055 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 RLN45839.1 - 0.065 12.7 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein DUF1677 PF07911.13 RLN45839.1 - 0.083 13.3 0.5 0.89 10.0 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1677) NTPase_1 PF03266.15 RLN45839.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_11 PF13086.6 RLN45839.1 - 0.15 11.8 0.0 0.49 10.1 0.0 1.9 1 1 1 2 2 2 0 AAA domain MCM PF00493.23 RLN45839.1 - 0.17 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain BPL_LplA_LipB PF03099.19 RLN45840.1 - 1.5e-20 73.4 0.0 2.7e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 RLN45840.1 - 0.0028 17.5 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Mitofilin PF09731.9 RLN45875.1 - 4.7e-49 167.8 24.9 1.1e-48 166.6 24.9 1.6 1 1 0 1 1 1 1 Mitochondrial inner membrane protein FtsK_gamma PF09397.10 RLN45875.1 - 0.0081 15.9 0.5 0.11 12.3 0.0 2.8 2 1 0 2 2 2 1 Ftsk gamma domain MRP-S31 PF15433.6 RLN45875.1 - 1.2 8.8 9.9 1.6 8.3 9.9 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Prominin PF05478.11 RLN45875.1 - 1.5 6.6 8.4 3.3 5.5 8.4 1.5 1 1 0 1 1 1 0 Prominin NAP PF00956.18 RLN45875.1 - 4.6 6.3 7.3 6.5 5.9 2.1 2.0 1 1 1 2 2 2 0 Nucleosome assembly protein (NAP) HIT PF01230.23 RLN45876.1 - 5.9e-07 30.1 0.3 1.7e-06 28.7 0.3 1.8 1 1 0 1 1 1 1 HIT domain PGA2 PF07543.12 RLN45877.1 - 0.094 12.7 2.2 0.61 10.1 0.4 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 CENP-B_dimeris PF09026.10 RLN45877.1 - 1.2 9.5 5.4 14 6.1 0.3 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain AAA_22 PF13401.6 RLN45900.1 - 0.0078 16.5 0.1 0.19 12.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain Ribosomal_60s PF00428.19 RLN45900.1 - 0.025 15.1 0.3 0.025 15.1 0.3 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein AAA_33 PF13671.6 RLN45900.1 - 0.058 13.5 0.0 0.11 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RLN45900.1 - 0.11 12.8 0.3 0.29 11.5 0.1 1.9 2 1 0 2 2 2 0 AAA ATPase domain Acyltransferase PF01553.21 RLN45914.1 - 1.9e-20 72.8 0.0 4e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase NAD_binding_4 PF07993.12 RLN45914.1 - 2.9e-15 56.1 0.0 4.6e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 RLN45914.1 - 4.3e-13 49.3 0.0 7.7e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein 6PGD PF00393.19 RLN45915.1 - 1.5e-14 54.0 0.3 1.7e-14 53.9 0.3 1.0 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain MadL PF03817.13 RLN45931.1 - 0.11 12.5 0.0 0.54 10.3 0.2 1.7 1 1 1 2 2 2 0 Malonate transporter MadL subunit Utp12 PF04003.12 RLN45938.1 - 0.0096 16.2 0.5 0.031 14.6 0.5 1.8 1 0 0 1 1 1 1 Dip2/Utp12 Family UTP15_C PF09384.10 RLN45938.1 - 0.029 14.1 0.5 4.2 7.1 0.0 2.7 3 0 0 3 3 3 0 UTP15 C terminal Conotoxin PF02950.17 RLN45938.1 - 0.05 14.6 0.5 0.05 14.6 0.5 2.8 3 0 0 3 3 3 0 Conotoxin SPATA9 PF15824.5 RLN45938.1 - 0.26 10.5 1.7 0.31 10.3 0.4 1.7 2 0 0 2 2 2 0 Spermatogenesis-associated protein 9 DEAD PF00270.29 RLN45939.1 - 1.2e-43 148.9 0.3 1.7e-43 148.4 0.3 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN45939.1 - 1.8e-29 102.3 1.3 5.4e-28 97.6 0.4 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN45939.1 - 6.2e-05 23.1 0.0 9.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 RLN45939.1 - 0.00083 18.6 0.1 0.0013 18.0 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 RLN45939.1 - 0.013 14.9 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.6 RLN45939.1 - 0.024 14.3 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain La PF05383.17 RLN45940.1 - 3.8e-18 65.3 0.1 6.9e-18 64.4 0.1 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 RLN45940.1 - 0.00015 21.5 0.0 0.0026 17.5 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4200 PF13863.6 RLN45941.1 - 8.2e-23 81.1 27.3 8.2e-23 81.1 27.3 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF4200) FUSC PF04632.12 RLN45941.1 - 0.042 12.4 20.0 0.38 9.2 7.6 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family Syntaxin-6_N PF09177.11 RLN45941.1 - 0.17 12.4 15.9 0.22 12.1 3.8 2.9 2 1 0 3 3 3 0 Syntaxin 6, N-terminal YnfE PF17452.2 RLN45941.1 - 0.33 11.3 7.5 0.31 11.3 0.7 2.8 2 0 0 2 2 2 0 Uncharacterized YnfE-like KMP11 PF03037.16 RLN45941.1 - 0.57 11.0 8.6 1.4 9.8 8.6 1.6 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 DUF1664 PF07889.12 RLN45941.1 - 10 6.2 13.2 0.4 10.7 1.8 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF2401 PF10287.9 RLN45942.1 - 3.1e-59 200.4 2.5 3.1e-59 200.4 2.5 2.0 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 RLN45942.1 - 5.6e-12 45.9 0.1 2e-11 44.2 0.1 2.0 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) DUF966 PF06136.13 RLN45942.1 - 6.7 6.3 7.9 9.9 5.8 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Pkinase_C PF00433.24 RLN45963.1 - 1.7e-08 35.0 0.9 3e-08 34.2 0.9 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain CN_hydrolase PF00795.22 RLN45964.1 - 9.9e-33 113.6 0.0 1.4e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 RLN45964.1 - 1.2e-24 86.8 0.1 4.5e-24 84.9 0.1 1.8 1 1 0 1 1 1 1 NAD synthase UCH PF00443.29 RLN45965.1 - 4.9e-27 95.0 0.6 9.6e-27 94.1 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN45965.1 - 2.5e-07 30.6 12.5 1.8e-05 24.5 12.5 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4330 PF14221.6 RLN45965.1 - 0.03 14.5 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) Cation_ATPase_C PF00689.21 RLN45966.1 - 1.8e-42 145.1 7.6 6.6e-42 143.3 0.3 2.7 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 RLN45966.1 - 1.7e-37 128.7 0.0 1.7e-37 128.7 0.0 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 RLN45966.1 - 9.6e-19 68.5 0.8 2.7e-18 67.0 0.8 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN45966.1 - 4.8e-16 58.6 0.0 1.2e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 RLN45966.1 - 8.5e-07 28.6 0.3 5.7e-06 25.9 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RLN45966.1 - 0.0007 19.4 0.2 0.02 14.6 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 RLN45966.1 - 0.16 12.3 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF4231 PF14015.6 RLN45966.1 - 1.1 9.8 4.7 51 4.4 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Phage_holin_2_3 PF16080.5 RLN45966.1 - 1.3 8.9 3.3 1.9 8.3 0.0 2.8 3 0 0 3 3 3 0 Bacteriophage holin family HP1 Pkinase PF00069.25 RLN45970.1 - 1e-49 169.3 0.0 1.4e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN45970.1 - 1.7e-44 152.1 0.0 2.3e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TauE PF01925.19 RLN45970.1 - 0.0042 16.8 3.2 0.0069 16.0 3.2 1.4 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE AzlD PF05437.12 RLN45970.1 - 0.035 14.3 5.6 0.11 12.7 5.6 1.8 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) APH PF01636.23 RLN45970.1 - 0.049 13.5 0.2 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN45970.1 - 0.062 12.6 0.1 0.12 11.7 0.0 1.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN45970.1 - 0.14 10.9 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase TMEM100 PF16311.5 RLN45970.1 - 0.18 11.4 2.9 0.4 10.3 2.9 1.5 1 0 0 1 1 1 0 Transmembrane protein 100 Pkinase PF00069.25 RLN45971.1 - 1.3e-48 165.7 0.0 4.4e-48 163.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN45971.1 - 4.9e-44 150.6 0.0 6.6e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN45971.1 - 0.062 13.2 0.0 0.23 11.4 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN45971.1 - 0.09 11.7 0.0 1.3 7.9 0.1 2.1 2 0 0 2 2 2 0 Haspin like kinase domain TauE PF01925.19 RLN45971.1 - 0.096 12.3 6.1 0.25 11.0 6.1 1.7 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE EphA2_TM PF14575.6 RLN45971.1 - 0.15 13.0 0.0 7.1 7.6 0.0 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 RLN45971.1 - 0.58 10.0 2.2 17 5.3 0.1 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF981 PF06168.11 RLN45971.1 - 0.59 10.0 6.3 2.2 8.2 7.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF981) MadL PF03817.13 RLN45971.1 - 0.81 9.7 4.4 0.53 10.3 0.4 2.4 2 0 0 2 2 2 0 Malonate transporter MadL subunit Pkinase PF00069.25 RLN45972.1 - 1.7e-49 168.6 0.0 2.2e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN45972.1 - 1.2e-44 152.6 0.0 1.5e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN45972.1 - 0.024 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4131 PF13567.6 RLN45972.1 - 0.026 14.2 6.3 0.02 14.5 4.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) APH PF01636.23 RLN45972.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN45972.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase 7TMR-DISM_7TM PF07695.11 RLN45972.1 - 0.17 11.8 3.5 0.26 11.1 3.5 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling TP53IP5 PF15331.6 RLN45973.1 - 0.013 15.7 0.7 0.03 14.5 0.7 1.6 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Pkinase_Tyr PF07714.17 RLN46015.1 - 1.9e-15 56.8 0.0 2.1e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN46015.1 - 4.6e-15 55.7 0.0 5.4e-15 55.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Aldo_ket_red PF00248.21 RLN46016.1 - 4.2e-33 114.8 0.0 2.5e-29 102.4 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Aldo_ket_red PF00248.21 RLN46017.1 - 1.4e-15 57.3 0.1 1.6e-15 57.1 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Dimer_Tnp_hAT PF05699.14 RLN46030.1 - 0.016 15.0 0.2 0.028 14.2 0.2 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region MULE PF10551.9 RLN46031.1 - 1.6e-08 34.8 0.6 1.6e-08 34.8 0.6 2.0 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 RLN46031.1 - 0.026 13.4 0.2 0.039 12.8 0.2 1.2 1 0 0 1 1 1 0 Transposase, Mutator family Helitron_like_N PF14214.6 RLN46056.1 - 3.2e-11 43.8 0.1 1.1e-10 42.0 0.0 1.9 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus HsbA PF12296.8 RLN46063.1 - 2.1 8.8 6.7 2.2 8.7 2.4 2.5 2 0 0 2 2 2 0 Hydrophobic surface binding protein A TPPK_C PF12555.8 RLN46063.1 - 4 7.6 7.9 2.9 8.0 1.1 3.4 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal CCDC71L PF15374.6 RLN46064.1 - 0.014 14.6 2.1 0.022 14.0 2.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L Syntaxin_2 PF14523.6 RLN46064.1 - 0.03 14.7 0.9 2.2 8.7 0.0 2.8 2 1 0 2 2 2 0 Syntaxin-like protein Pes-10 PF07149.11 RLN46064.1 - 0.078 12.0 1.1 0.11 11.5 1.1 1.2 1 0 0 1 1 1 0 Pes-10 FlgN PF05130.12 RLN46064.1 - 0.27 11.7 7.2 0.2 12.2 2.6 2.4 2 0 0 2 2 2 0 FlgN protein V_ATPase_I PF01496.19 RLN46064.1 - 0.9 7.4 2.3 1 7.2 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NIF PF03031.18 RLN46147.1 - 0.053 13.3 0.0 0.16 11.8 0.0 1.8 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase TFIIA PF03153.13 RLN46147.1 - 0.18 11.7 9.7 0.3 11.1 9.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CAML PF14963.6 RLN46147.1 - 0.19 11.9 2.0 0.35 11.0 2.0 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Med3 PF11593.8 RLN46147.1 - 1.1 8.3 10.3 1.8 7.7 10.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal eIF2A PF08662.11 RLN46148.1 - 2.5e-53 180.9 3.3 6.8e-49 166.4 0.8 3.3 4 0 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 RLN46148.1 - 6e-07 29.7 0.1 3.1 8.2 0.0 5.5 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 RLN46148.1 - 0.00011 20.4 0.1 0.00058 18.0 0.0 1.9 1 1 0 2 2 2 1 IKI3 family WD40 PF00400.32 RLN46148.1 - 0.00014 22.6 0.6 12 7.0 0.0 5.2 6 0 0 6 6 6 1 WD domain, G-beta repeat Lactonase PF10282.9 RLN46148.1 - 0.15 11.2 0.0 3.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Dimer_Tnp_hAT PF05699.14 RLN46158.1 - 1.6e-11 43.8 1.9 1.9e-11 43.6 0.6 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region PlyB_C PF18684.1 RLN46158.1 - 0.024 14.3 0.0 0.058 13.1 0.0 1.6 2 0 0 2 2 2 0 Pleurotolysin B C-terminal domain zf-C2H2_3rep PF18868.1 RLN46158.1 - 0.1 13.3 1.9 0.31 11.7 0.1 2.5 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats YscO-like PF16789.5 RLN46158.1 - 0.14 12.2 0.2 0.14 12.2 0.2 1.7 2 0 0 2 2 2 0 YscO-like protein ELH PF02323.15 RLN46158.1 - 0.45 9.9 2.3 1 8.7 0.1 2.1 2 0 0 2 2 2 0 Egg-laying hormone precursor Myosin_head PF00063.21 RLN46159.1 - 1.5e-11 43.3 0.0 1.7e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 RLN46159.1 - 0.00014 22.2 0.0 0.00017 21.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RLN46159.1 - 0.0063 16.2 0.1 0.0076 16.0 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RLN46159.1 - 0.01 16.1 0.0 0.011 16.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RLN46159.1 - 0.016 15.6 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 RLN46159.1 - 0.036 13.1 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein PIF1 PF05970.14 RLN46159.1 - 0.057 12.6 0.0 0.059 12.5 0.0 1.0 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.22 RLN46159.1 - 0.086 13.2 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_6 PF12774.7 RLN46159.1 - 0.098 11.6 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region ATPase PF06745.13 RLN46159.1 - 0.1 12.0 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 KaiC TsaE PF02367.17 RLN46159.1 - 0.14 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 RLN46159.1 - 0.14 12.7 0.1 0.21 12.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RLN46159.1 - 0.18 11.1 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Filament PF00038.21 RLN46160.1 - 0.0082 15.8 0.9 0.0082 15.8 0.9 2.1 2 0 0 2 2 2 1 Intermediate filament protein Pox_A_type_inc PF04508.12 RLN46160.1 - 0.073 12.9 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat CENP-F_leu_zip PF10473.9 RLN46160.1 - 0.25 11.4 8.4 0.41 10.7 0.7 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4686 PF15742.5 RLN46160.1 - 0.27 10.3 3.4 0.28 10.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4686) Tropomyosin_1 PF12718.7 RLN46160.1 - 0.51 10.5 13.7 0.52 10.5 5.7 2.4 2 0 0 2 2 2 0 Tropomyosin like HR1 PF02185.16 RLN46160.1 - 0.75 10.0 4.4 8.1 6.6 0.3 2.7 2 0 0 2 2 2 0 Hr1 repeat HAP1_N PF04849.13 RLN46160.1 - 1 8.5 7.2 0.22 10.7 0.7 2.3 2 1 0 2 2 2 0 HAP1 N-terminal conserved region Fez1 PF06818.15 RLN46160.1 - 2.4 8.6 6.8 7.9 6.9 6.8 1.9 1 1 0 1 1 1 0 Fez1 Tropomyosin PF00261.20 RLN46160.1 - 6.4 6.1 16.5 7.5 5.8 1.1 3.1 2 1 1 3 3 3 0 Tropomyosin zf-CCHC PF00098.23 RLN46172.1 - 1.2e-06 28.3 3.6 1.2e-06 28.3 3.6 2.4 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.17 RLN46172.1 - 0.00037 20.7 0.1 0.00077 19.7 0.1 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 RLN46172.1 - 6.5 6.7 8.5 0.1 12.4 1.0 2.0 2 0 0 2 2 2 0 Zinc knuckle BTB_2 PF02214.22 RLN46191.1 - 2.2e-17 63.2 0.0 7.6e-17 61.5 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Crust_neuro_H PF03858.13 RLN46192.1 - 0.065 14.1 0.3 0.25 12.2 0.3 2.0 1 0 0 1 1 1 0 Crustacean neurohormone H PseudoU_synth_2 PF00849.22 RLN46193.1 - 3.2e-28 98.8 0.0 5.9e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ank_2 PF12796.7 RLN46194.1 - 2.4e-50 169.1 12.0 2e-14 53.9 0.3 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN46194.1 - 9.8e-31 105.7 0.1 6.7e-09 36.1 0.0 5.6 4 2 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN46194.1 - 2.9e-29 97.8 0.2 0.0053 17.2 0.0 7.5 7 0 0 7 7 7 7 Ankyrin repeat Ank PF00023.30 RLN46194.1 - 7.7e-28 95.7 2.1 0.00059 20.2 0.0 7.4 6 1 1 7 7 7 7 Ankyrin repeat Ank_5 PF13857.6 RLN46194.1 - 1.3e-23 82.8 1.7 1.6e-05 25.1 0.0 6.0 2 2 4 6 6 6 5 Ankyrin repeats (many copies) TPR_2 PF07719.17 RLN46194.1 - 9.1e-08 31.7 8.9 0.0008 19.3 0.7 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN46194.1 - 5.6e-06 25.9 9.2 0.0079 16.0 0.6 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN46194.1 - 0.00047 19.8 1.8 0.0014 18.3 1.8 1.9 1 0 0 1 1 1 1 TPR repeat TPR_19 PF14559.6 RLN46194.1 - 0.013 16.0 3.7 0.013 16.0 3.7 3.0 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN46194.1 - 0.057 13.7 6.1 1.2 9.5 0.3 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN46194.1 - 0.064 13.9 11.8 0.34 11.6 2.3 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 RLN46194.1 - 0.19 11.8 0.9 3.8 7.7 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 RLN46194.1 - 0.2 11.8 8.3 0.39 10.9 2.2 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN46194.1 - 0.26 12.2 5.0 3.5 8.7 0.4 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN46194.1 - 0.44 10.8 6.7 0.13 12.5 3.1 2.1 2 0 0 2 2 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Glyoxalase_6 PF18029.1 RLN46194.1 - 3.7 8.4 6.8 0.58 11.0 0.7 2.9 3 2 0 3 3 3 0 Glyoxalase-like domain Aldo_ket_red PF00248.21 RLN46195.1 - 6.5e-70 235.6 0.0 7.3e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase_Tyr PF07714.17 RLN46196.1 - 1.7e-21 76.6 0.0 3.8e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN46196.1 - 9.4e-19 67.8 0.0 3.5e-18 65.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain FHA PF00498.26 RLN46196.1 - 6.4e-16 58.5 0.0 1.2e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RLN46196.1 - 4e-07 30.3 0.0 2.1e-06 28.0 0.0 2.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF1192 PF06698.11 RLN46196.1 - 0.018 15.1 1.6 0.018 15.1 1.6 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) ABC_membrane PF00664.23 RLN46198.1 - 1.2e-48 166.2 11.5 1.6e-48 165.7 11.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN46198.1 - 3.8e-34 118.2 0.0 8.5e-34 117.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN46198.1 - 6.3e-06 25.8 2.6 4.3e-05 23.1 0.1 2.6 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RLN46198.1 - 0.013 15.7 0.0 0.048 13.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RLN46198.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ABC_ATPase PF09818.9 RLN46198.1 - 0.026 13.3 0.0 0.055 12.3 0.0 1.5 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_29 PF13555.6 RLN46198.1 - 0.034 13.9 0.1 0.094 12.5 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 RLN46198.1 - 0.042 13.6 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein SbcCD_C PF13558.6 RLN46198.1 - 0.053 13.8 0.8 0.74 10.1 0.8 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 RLN46198.1 - 0.15 12.6 1.1 0.32 11.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.23 RLN46199.1 - 1.1e-106 356.4 24.7 3.1e-54 184.5 4.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN46199.1 - 4.4e-48 163.3 0.4 4.8e-36 124.3 0.1 2.8 3 0 0 3 3 2 2 ABC transporter RsgA_GTPase PF03193.16 RLN46199.1 - 3.4e-07 30.3 0.0 0.0053 16.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 RLN46199.1 - 1e-05 25.1 0.4 7.1e-05 22.3 0.1 2.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RLN46199.1 - 1.1e-05 25.1 0.9 0.087 12.6 0.1 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN46199.1 - 1.1e-05 25.7 0.3 0.045 14.0 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 RLN46199.1 - 0.00029 21.3 1.7 0.033 14.6 0.0 3.1 3 0 0 3 3 2 1 AAA ATPase domain AAA_25 PF13481.6 RLN46199.1 - 0.00045 19.8 0.1 6 6.4 0.1 3.4 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 RLN46199.1 - 0.0016 18.0 0.0 2 7.9 0.0 2.7 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_30 PF13604.6 RLN46199.1 - 0.0028 17.4 0.9 0.42 10.3 0.1 3.3 3 1 0 3 3 2 1 AAA domain AAA_28 PF13521.6 RLN46199.1 - 0.0051 17.1 0.8 0.42 10.8 0.1 2.8 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 RLN46199.1 - 0.0056 15.5 0.7 0.037 12.8 0.3 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA PF00004.29 RLN46199.1 - 0.0097 16.3 1.5 0.26 11.7 0.3 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 RLN46199.1 - 0.011 15.7 0.1 1.3 9.0 0.1 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase IstB_IS21 PF01695.17 RLN46199.1 - 0.012 15.3 0.0 1.7 8.4 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_33 PF13671.6 RLN46199.1 - 0.017 15.3 0.2 14 5.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain DEAD PF00270.29 RLN46199.1 - 0.023 14.4 0.4 0.57 9.9 0.3 2.5 2 1 0 2 2 2 0 DEAD/DEAH box helicase Zeta_toxin PF06414.12 RLN46199.1 - 0.05 12.9 0.0 0.54 9.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin G-alpha PF00503.20 RLN46199.1 - 0.062 12.5 0.0 2.6 7.1 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_15 PF13175.6 RLN46199.1 - 0.11 12.1 0.0 3.1 7.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.7 RLN46199.1 - 0.12 11.2 0.0 6.6 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.22 RLN46199.1 - 0.15 12.5 0.1 24 5.4 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 RLN46199.1 - 0.18 12.3 0.0 24 5.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain MoaE PF02391.17 RLN46199.1 - 0.24 11.7 1.1 0.63 10.3 0.2 2.2 2 0 0 2 2 1 0 MoaE protein SR-25 PF10500.9 RLN46236.1 - 0.04 13.5 4.7 0.057 13.0 4.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 RLN46236.1 - 0.37 11.5 8.9 0.71 10.6 8.9 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein AF-4 PF05110.13 RLN46236.1 - 0.68 7.9 7.3 0.82 7.7 7.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PhoLip_ATPase_C PF16212.5 RLN46338.1 - 1.5e-73 247.7 10.0 1.5e-73 247.7 10.0 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RLN46338.1 - 9.4e-19 66.9 2.9 9.4e-19 66.9 2.9 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RLN46338.1 - 1.4e-11 45.0 0.9 3.3e-06 27.5 0.2 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN46338.1 - 8.8e-11 41.7 0.2 9.9e-09 35.2 0.0 3.2 3 0 0 3 3 3 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RLN46338.1 - 1.1e-06 28.3 0.0 5.8e-06 26.0 0.0 2.3 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RLN46338.1 - 0.002 17.9 0.1 0.0042 16.9 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CDP-OH_P_tran_2 PF08009.11 RLN46338.1 - 1.6 8.7 6.9 1.3 8.9 0.8 2.9 2 0 0 2 2 2 0 CDP-alcohol phosphatidyltransferase 2 MMR_HSR1 PF01926.23 RLN46396.1 - 1.4e-12 47.7 0.0 8.1e-12 45.2 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase HSCB_C PF07743.13 RLN46396.1 - 4.3e-08 33.5 0.6 1.6e-07 31.7 0.6 2.0 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain RsgA_GTPase PF03193.16 RLN46396.1 - 3.3e-05 23.8 0.3 0.0097 15.8 0.3 2.6 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 RLN46396.1 - 0.00019 21.0 0.0 0.0018 17.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 RLN46396.1 - 0.0089 16.1 0.0 0.025 14.6 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Roc PF08477.13 RLN46396.1 - 0.013 15.7 0.1 0.27 11.4 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 RLN46396.1 - 0.025 13.9 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 Septin RNA_helicase PF00910.22 RLN46396.1 - 0.031 14.7 0.0 11 6.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 RLN46396.1 - 0.048 14.0 0.2 0.47 10.8 0.0 2.4 1 1 0 2 2 2 0 AAA ATPase domain Surp PF01805.20 RLN46397.1 - 1.3e-35 121.1 1.0 1.9e-16 59.7 0.1 2.7 3 0 0 3 3 3 2 Surp module PRP21_like_P PF12230.8 RLN46397.1 - 8.8e-21 74.8 14.3 5.2e-13 49.4 7.4 4.1 3 1 1 4 4 4 2 Pre-mRNA splicing factor PRP21 like protein Sporozoite_P67 PF05642.11 RLN46397.1 - 0.0002 19.6 3.5 0.0002 19.6 3.5 1.9 2 0 0 2 2 2 1 Sporozoite P67 surface antigen ubiquitin PF00240.23 RLN46397.1 - 0.0011 18.6 0.0 0.0047 16.7 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin family DGF-1_C PF11040.8 RLN46397.1 - 0.044 13.8 2.2 0.09 12.8 0.2 2.6 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DDHD PF02862.17 RLN46397.1 - 0.47 10.6 0.0 0.47 10.6 0.0 2.3 2 1 0 2 2 2 0 DDHD domain FH2 PF02181.23 RLN46399.1 - 1.6e-85 287.5 2.1 2.7e-85 286.8 0.4 2.2 2 1 0 2 2 2 1 Formin Homology 2 Domain CCDC53 PF10152.9 RLN46399.1 - 6.2e-69 231.3 37.0 4e-09 37.1 0.3 10.6 11 0 0 11 11 11 8 Subunit CCDC53 of WASH complex Drf_FH3 PF06367.16 RLN46399.1 - 2.7e-19 69.5 8.2 2.7e-09 36.9 0.1 2.8 3 0 0 3 3 3 2 Diaphanous FH3 Domain Drf_GBD PF06371.13 RLN46399.1 - 5.9e-12 45.5 0.0 3.7e-11 42.9 0.0 2.3 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain HSBP1 PF06825.12 RLN46399.1 - 0.17 11.8 5.8 1.5 8.7 0.4 2.7 2 0 0 2 2 2 0 Heat shock factor binding protein 1 EnY2 PF10163.9 RLN46432.1 - 1.1e-22 80.1 1.9 3.6e-17 62.5 1.4 2.9 2 1 0 2 2 2 2 Transcription factor e(y)2 DUF4800 PF16057.5 RLN46432.1 - 0.011 15.0 0.5 0.015 14.5 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) Ribosomal_S16 PF00886.19 RLN46433.1 - 4.3e-21 74.7 0.0 1.1e-20 73.4 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein S16 Glucan_synthase PF02364.15 RLN46434.1 - 2.1e-187 625.0 11.5 3.3e-167 558.1 6.1 2.4 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 RLN46434.1 - 1.3e-23 83.7 1.1 1.3e-22 80.5 1.1 2.5 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 CcmE PF03100.15 RLN46434.1 - 0.098 12.6 0.3 1.5 8.8 0.2 2.8 2 0 0 2 2 2 0 CcmE FHA PF00498.26 RLN46435.1 - 1.4e-07 31.7 0.0 2.9e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain Nop14 PF04147.12 RLN46436.1 - 2.1e-196 655.0 48.0 2.4e-196 654.7 48.0 1.0 1 0 0 1 1 1 1 Nop14-like family Noc2 PF03715.13 RLN46436.1 - 0.77 8.9 0.0 0.77 8.9 0.0 2.3 3 0 0 3 3 3 0 Noc2p family HTH_Tnp_1 PF01527.20 RLN46437.1 - 0.087 13.2 0.0 0.093 13.1 0.0 1.1 1 0 0 1 1 1 0 Transposase FYVE PF01363.21 RLN46438.1 - 3.4e-12 46.3 10.6 6e-12 45.5 10.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN46438.1 - 0.019 15.1 3.5 0.067 13.4 3.5 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger FANCD2OS PF15124.6 RLN46438.1 - 0.11 12.7 0.8 0.35 11.1 0.1 2.1 2 0 0 2 2 2 0 FANCD2 opposite strand protein GAT PF03127.14 RLN46438.1 - 0.16 12.3 0.2 0.37 11.1 0.2 1.6 1 0 0 1 1 1 0 GAT domain FYVE PF01363.21 RLN46439.1 - 1e-12 48.0 8.8 2.6e-12 46.7 8.8 1.7 1 0 0 1 1 1 1 FYVE zinc finger DHR10 PF18595.1 RLN46439.1 - 0.039 14.0 3.4 0.098 12.7 3.4 1.7 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DivIC PF04977.15 RLN46439.1 - 0.13 12.1 0.6 0.34 10.7 0.6 1.7 1 0 0 1 1 1 0 Septum formation initiator LegC3_N PF18654.1 RLN46439.1 - 0.16 11.2 3.7 0.46 9.7 3.7 1.7 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain T3SSipB PF16535.5 RLN46439.1 - 0.46 10.9 6.4 2.5 8.6 0.7 2.8 2 0 0 2 2 2 0 Type III cell invasion protein SipB DUF3209 PF11483.8 RLN46439.1 - 0.54 10.7 4.8 0.39 11.2 2.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3209) ABC_tran_CTD PF16326.5 RLN46439.1 - 0.73 10.1 3.2 13 6.2 0.9 2.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain FYVE_2 PF02318.16 RLN46439.1 - 3.7 7.8 9.5 0.5 10.6 4.2 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger SesA PF17107.5 RLN46439.1 - 4.2 7.6 5.2 4.1 7.6 0.3 3.1 4 0 0 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases MscS_porin PF12795.7 RLN46439.1 - 4.7 6.7 9.8 0.57 9.7 4.2 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain FYVE PF01363.21 RLN46523.1 - 0.003 17.6 8.0 0.0068 16.5 8.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger N6-adenineMlase PF10237.9 RLN46524.1 - 5.7e-58 195.2 6.6 3.3e-30 105.0 1.1 2.4 1 1 1 2 2 2 2 Probable N6-adenine methyltransferase DDE_3 PF13358.6 RLN46524.1 - 0.0028 17.4 0.1 0.006 16.3 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-HC2 PF13490.6 RLN46524.1 - 0.023 15.0 9.0 0.47 10.8 2.3 2.7 2 0 0 2 2 2 0 Putative zinc-finger FERM_M PF00373.18 RLN46524.1 - 0.053 13.9 3.5 1.8 9.0 0.2 2.5 2 0 0 2 2 2 0 FERM central domain LPD26 PF18842.1 RLN46524.1 - 0.37 10.8 1.5 17 5.5 0.1 2.5 2 0 0 2 2 2 0 Large polyvalent protein associated domain 26 RAC_head PF16717.5 RLN46524.1 - 2.1 9.3 6.4 26 5.9 3.9 2.5 2 0 0 2 2 2 0 Ribosome-associated complex head domain Nop14 PF04147.12 RLN46524.1 - 9.7 4.3 15.4 2.5 6.2 12.3 1.4 2 0 0 2 2 2 0 Nop14-like family Cyclin_N PF00134.23 RLN46525.1 - 2.6e-07 30.4 1.5 4e-07 29.8 1.5 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Palm_thioest PF02089.15 RLN46526.1 - 2.8e-48 164.9 0.0 3.5e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 RLN46526.1 - 0.0014 18.2 0.1 0.0042 16.6 0.1 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 RLN46526.1 - 0.0037 17.0 0.1 0.11 12.2 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Lipase_2 PF01674.18 RLN46526.1 - 0.0075 15.8 0.1 0.03 13.8 0.1 2.0 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.20 RLN46526.1 - 0.0086 15.7 0.1 0.017 14.8 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN46526.1 - 0.032 14.8 0.0 0.042 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 RLN46526.1 - 0.039 13.5 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase NAD_binding_10 PF13460.6 RLN46526.1 - 0.11 12.4 0.5 0.28 11.0 0.3 1.7 2 0 0 2 2 2 0 NAD(P)H-binding CHRD PF07452.12 RLN46526.1 - 0.25 12.3 2.0 1.7 9.6 0.0 2.7 2 1 1 3 3 3 0 CHRD domain RAP PF08373.10 RLN46538.1 - 1.2e-07 31.7 0.1 1.5e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 RAP domain DUF3712 PF12505.8 RLN46539.1 - 3.5e-15 56.4 0.4 7.7e-15 55.3 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Rax2 PF12768.7 RLN46539.1 - 0.0089 15.5 1.1 1.3 8.4 0.0 2.3 2 0 0 2 2 2 2 Cortical protein marker for cell polarity Fumarate_red_C PF02300.17 RLN46539.1 - 0.017 15.2 0.4 0.03 14.4 0.4 1.3 1 0 0 1 1 1 0 Fumarate reductase subunit C DUF3989 PF13150.6 RLN46539.1 - 0.028 14.2 1.7 0.051 13.3 1.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3989) Orf78 PF06024.12 RLN46539.1 - 0.14 12.5 0.1 0.24 11.7 0.1 1.5 1 0 0 1 1 1 0 Orf78 (ac78) DUF3712 PF12505.8 RLN46540.1 - 5.6e-16 58.9 0.1 1.8e-15 57.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) PrgI PF12666.7 RLN46540.1 - 0.071 13.8 1.1 0.2 12.4 1.1 1.8 1 0 0 1 1 1 0 PrgI family protein Orf78 PF06024.12 RLN46540.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Synaptobrevin PF00957.21 RLN46540.1 - 0.84 9.5 3.9 1.6 8.6 3.9 1.4 1 0 0 1 1 1 0 Synaptobrevin SCIMP PF15050.6 RLN46540.1 - 5.1 7.6 5.2 8.4 6.9 5.2 1.3 1 0 0 1 1 1 0 SCIMP protein Arm PF00514.23 RLN46541.1 - 2e-35 119.7 13.8 8.1e-09 35.2 0.0 9.2 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN46541.1 - 4.1e-19 67.0 5.2 0.064 13.5 0.1 8.2 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 RLN46541.1 - 8.6e-16 58.1 10.4 0.0024 18.2 0.0 5.6 2 2 3 6 6 6 5 HEAT repeats HEAT_EZ PF13513.6 RLN46541.1 - 3e-13 49.9 16.2 0.00089 19.7 0.1 7.5 7 1 1 8 8 8 5 HEAT-like repeat Cnd1 PF12717.7 RLN46541.1 - 5.2e-13 49.4 1.4 0.014 15.5 0.0 4.8 3 2 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 RLN46541.1 - 2.2e-07 29.9 2.5 0.0047 15.5 0.0 3.3 2 1 1 3 3 3 2 Adaptin N terminal region DNA_alkylation PF08713.11 RLN46541.1 - 2.9e-07 30.4 0.0 0.85 9.3 0.0 3.9 2 1 2 4 4 4 3 DNA alkylation repair enzyme CLASP_N PF12348.8 RLN46541.1 - 1.5e-06 27.9 0.3 0.16 11.5 0.0 3.7 3 1 0 3 3 3 2 CLASP N terminal CHASE6_C PF17150.4 RLN46541.1 - 3.1e-06 27.7 0.6 25 5.6 0.0 6.1 6 0 0 6 6 6 0 C-terminal domain of two-partite extracellular sensor domain V-ATPase_H_C PF11698.8 RLN46541.1 - 0.00097 19.2 0.1 11 6.2 0.0 4.3 3 2 2 5 5 5 0 V-ATPase subunit H Atx10homo_assoc PF09759.9 RLN46541.1 - 0.00097 19.1 0.6 2.5 8.2 0.1 4.3 3 1 2 5 5 5 1 Spinocerebellar ataxia type 10 protein domain HEAT_UF PF18817.1 RLN46541.1 - 0.0021 18.3 0.2 0.24 11.7 0.0 3.8 4 0 0 4 4 4 1 Repeat of uncharacterized protein PH0542 Proteasom_PSMB PF10508.9 RLN46541.1 - 0.0027 16.3 5.1 0.016 13.8 0.2 3.3 2 1 1 4 4 4 1 Proteasome non-ATPase 26S subunit Arm_2 PF04826.13 RLN46541.1 - 0.0081 15.6 0.8 12 5.3 0.0 4.2 3 1 1 5 5 5 0 Armadillo-like Mo25 PF08569.11 RLN46541.1 - 0.011 15.1 0.1 0.5 9.7 0.1 2.9 1 1 1 2 2 2 0 Mo25-like Npa1 PF11707.8 RLN46541.1 - 0.018 14.4 0.1 0.79 9.0 0.0 2.6 2 0 0 2 2 2 0 Ribosome 60S biogenesis N-terminal DUF3144 PF11342.8 RLN46541.1 - 0.091 13.1 0.1 11 6.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3144) HEAT_PBS PF03130.16 RLN46541.1 - 0.26 12.1 12.7 16 6.5 0.2 5.7 6 0 0 6 6 5 0 PBS lyase HEAT-like repeat DUF3730 PF12530.8 RLN46541.1 - 0.41 10.2 5.2 1.1 8.8 0.0 3.8 4 2 0 4 4 4 0 Protein of unknown function (DUF3730) UAA PF08449.11 RLN46542.1 - 7.5e-48 163.3 18.3 1.3e-47 162.4 18.3 1.4 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 RLN46542.1 - 1.4e-05 24.6 18.4 2.2e-05 24.0 2.5 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 RLN46542.1 - 0.0011 18.2 5.4 0.0024 17.1 0.2 3.1 2 1 2 4 4 4 1 Nucleotide-sugar transporter EamA PF00892.20 RLN46542.1 - 0.0065 16.6 11.2 0.0065 16.6 11.2 2.3 2 0 0 2 2 2 1 EamA-like transporter family CRT-like PF08627.10 RLN46542.1 - 0.03 13.3 14.9 0.056 12.4 14.1 1.7 1 1 1 2 2 2 0 CRT-like, chloroquine-resistance transporter-like PIRT PF15099.6 RLN46542.1 - 0.081 12.5 0.0 0.081 12.5 0.0 2.6 3 1 0 3 3 3 0 Phosphoinositide-interacting protein family Importin_rep_3 PF18806.1 RLN46543.1 - 0.055 13.5 0.1 0.083 12.9 0.1 1.2 1 0 0 1 1 1 0 Importin 13 repeat YEATS PF03366.16 RLN46544.1 - 4.8e-26 90.6 0.0 8.2e-26 89.8 0.0 1.4 1 0 0 1 1 1 1 YEATS family OspD PF03207.13 RLN46544.1 - 0.021 14.2 0.8 0.029 13.7 0.8 1.1 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) FHA PF00498.26 RLN46545.1 - 3e-10 40.3 0.0 6.4e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RLN46545.1 - 9.5e-05 22.7 0.1 0.00029 21.1 0.1 1.8 1 1 1 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain DUF745 PF05335.13 RLN46545.1 - 0.26 11.0 1.3 0.53 10.0 1.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF745) DUF543 PF04418.12 RLN46546.1 - 0.029 14.4 3.1 0.029 14.4 3.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF543) PDCD2_C PF04194.13 RLN46547.1 - 1.7e-33 116.2 1.6 1.9e-33 116.0 0.4 1.7 1 1 1 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain DUF4810 PF16068.5 RLN46547.1 - 0.096 13.2 0.2 0.22 12.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4810) PAXX PF15384.6 RLN46548.1 - 0.012 15.4 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 ThiF PF00899.21 RLN46552.1 - 1.8e-22 79.9 0.1 6.8e-22 78.0 0.1 1.8 1 1 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 RLN46552.1 - 0.14 11.5 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Nup88 PF10168.9 RLN46553.1 - 1.3e-16 59.6 6.4 2.8e-06 25.5 4.2 4.2 4 0 0 4 4 4 4 Nuclear pore component DUF2203 PF09969.9 RLN46553.1 - 1.6 9.4 4.6 0.59 10.9 0.6 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) CAML PF14963.6 RLN46606.1 - 0.41 10.7 5.8 0.97 9.5 5.8 1.5 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand FXR_C3 PF16097.5 RLN46606.1 - 4.1 8.2 9.6 2.5 8.9 0.1 2.9 3 0 0 3 3 3 0 Fragile X-related 1 protein C-terminal region 3 mTERF PF02536.14 RLN46607.1 - 1.7e-14 53.5 0.0 3.2e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 mTERF Myb_DNA-bind_4 PF13837.6 RLN46607.1 - 0.006 16.9 0.1 1.2 9.5 0.1 2.6 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain SLAIN PF15301.6 RLN46607.1 - 0.17 11.1 4.8 0.05 12.8 1.4 1.8 2 0 0 2 2 2 0 SLAIN motif-containing family rRNA_processing PF08524.11 RLN46607.1 - 1.4 9.0 7.4 6.1 6.9 1.9 2.3 2 0 0 2 2 2 0 rRNA processing Guanylate_cyc PF00211.20 RLN46608.1 - 6.5e-10 38.9 0.0 1.1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 RLN46610.1 - 2.7e-11 43.4 0.0 4.9e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 RLN46611.1 - 2.8e-12 46.7 0.0 5e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF1467 PF07330.12 RLN46611.1 - 0.041 13.8 1.5 0.13 12.2 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1467) NTF2 PF02136.20 RLN46643.1 - 3.7e-08 34.0 0.0 4.2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain 7TMR-HDED PF07697.11 RLN46644.1 - 0.0079 16.3 1.4 0.037 14.2 0.5 2.3 2 0 0 2 2 2 1 7TM-HD extracellular HEAT_2 PF13646.6 RLN46644.1 - 0.0093 16.3 14.7 0.078 13.4 1.9 4.5 3 1 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 RLN46644.1 - 0.23 12.0 4.2 3 8.4 0.2 3.8 3 0 0 3 3 3 0 HEAT-like repeat SNARE PF05739.19 RLN46645.1 - 0.00015 21.7 2.4 0.00027 20.9 0.4 2.2 2 0 0 2 2 2 1 SNARE domain GP41 PF00517.17 RLN46645.1 - 0.078 12.9 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Retroviral envelope protein PgaD PF13994.6 RLN46646.1 - 0.0099 15.9 0.3 0.017 15.2 0.3 1.5 1 1 0 1 1 1 1 PgaD-like protein EphA2_TM PF14575.6 RLN46646.1 - 0.092 13.6 0.3 5.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Zn_peptidase_2 PF04298.12 RLN46646.1 - 0.092 12.1 1.0 0.6 9.5 0.0 2.1 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase ECSCR PF15820.5 RLN46646.1 - 0.17 11.7 2.0 4.1 7.3 0.8 2.3 1 1 1 2 2 2 0 Endothelial cell-specific chemotaxis regulator PigN PF04987.14 RLN46646.1 - 8.7 5.1 12.3 3.2 6.5 0.5 2.2 1 1 1 2 2 2 0 Phosphatidylinositolglycan class N (PIG-N) DUF3357 PF11837.8 RLN46647.1 - 3.8 8.0 9.7 35 4.9 0.1 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF3357) PIG-P PF08510.12 RLN46648.1 - 0.021 14.7 7.5 0.021 14.7 7.5 2.1 3 0 0 3 3 3 0 PIG-P Tim54 PF11711.8 RLN46648.1 - 0.42 9.3 0.4 0.6 8.8 0.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2207 PF09972.9 RLN46649.1 - 0.021 13.6 0.0 0.021 13.6 0.0 2.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF5083 PF16890.5 RLN46649.1 - 1.2 8.8 4.6 0.26 11.0 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5083) Sensor PF13796.6 RLN46649.1 - 7.9 6.5 34.2 0.11 12.6 0.3 3.4 2 1 2 4 4 4 0 Putative sensor SCP2_2 PF13530.6 RLN46650.1 - 0.05 14.0 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Sterol carrier protein domain SCP2 PF02036.17 RLN46650.1 - 0.056 13.9 0.0 0.25 11.9 0.0 2.1 1 1 0 1 1 1 0 SCP-2 sterol transfer family WD40 PF00400.32 RLN46652.1 - 8.1e-12 45.5 9.0 0.29 12.1 0.0 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN46652.1 - 2e-05 24.8 0.0 0.11 12.8 0.0 3.2 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RLN46652.1 - 0.00087 18.7 0.1 0.047 13.0 0.0 2.0 1 1 1 2 2 2 2 WD40-like domain PQQ_3 PF13570.6 RLN46652.1 - 0.0029 18.0 0.0 0.88 10.1 0.0 3.3 3 0 0 3 3 3 1 PQQ-like domain PHTB1_N PF14727.6 RLN46652.1 - 0.012 15.0 0.0 0.06 12.7 0.0 2.0 1 1 2 3 3 3 0 PTHB1 N-terminus Antimicrobial22 PF16047.5 RLN46652.1 - 0.083 12.8 1.1 0.18 11.7 1.1 1.6 1 0 0 1 1 1 0 Frog antimicrobial peptide YL1 PF05764.13 RLN46652.1 - 6.9 6.7 7.2 9.8 6.2 7.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein PDZ PF00595.24 RLN46653.1 - 7.9e-07 29.3 0.0 3e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 RLN46653.1 - 9.7e-06 25.3 0.0 0.032 14.1 0.0 3.0 3 0 0 3 3 3 2 PDZ domain Fer4_8 PF13183.6 RLN46654.1 - 0.00012 22.4 0.1 0.00013 22.3 0.1 1.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 RLN46654.1 - 0.0016 19.0 0.1 0.0018 18.8 0.1 1.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 RLN46654.1 - 0.002 18.2 0.1 0.0025 17.9 0.1 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pkinase PF00069.25 RLN46655.1 - 6.1e-27 94.6 0.0 1e-26 93.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN46655.1 - 3.6e-26 92.0 0.0 6.8e-26 91.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase CENP-F_leu_zip PF10473.9 RLN46662.1 - 3 7.9 9.5 6.2 6.8 7.8 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A_type_inc PF04508.12 RLN46662.1 - 4.8 7.2 5.7 12 5.9 0.0 3.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat 3HCDH_N PF02737.18 RLN46698.1 - 7.6e-55 185.6 1.4 1.1e-54 185.1 0.2 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 RLN46698.1 - 4e-44 150.8 3.3 1.5e-43 148.9 2.1 2.4 2 1 1 3 3 3 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 RLN46698.1 - 2.8e-34 117.6 0.0 2.2e-23 82.7 0.0 3.4 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 RLN46698.1 - 1.5e-29 103.6 1.4 1.5e-29 103.6 1.4 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 RLN46698.1 - 0.023 14.9 0.8 0.048 13.8 0.1 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 RLN46698.1 - 0.033 13.5 0.3 0.12 11.6 0.2 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 RLN46698.1 - 0.047 13.9 0.1 0.15 12.3 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 RLN46698.1 - 0.068 13.7 0.5 0.21 12.2 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ARL2_Bind_BART PF11527.8 RLN46699.1 - 1.5e-32 112.1 1.4 2.6e-32 111.4 0.0 2.1 2 1 0 2 2 2 1 The ARF-like 2 binding protein BART DSBA PF01323.20 RLN46699.1 - 0.77 9.5 6.8 0.38 10.5 3.8 2.1 2 0 0 2 2 2 0 DSBA-like thioredoxin domain DUF572 PF04502.13 RLN46699.1 - 3.2 7.3 27.2 5.6 6.5 27.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) RRM_1 PF00076.22 RLN46700.1 - 5.8e-11 42.1 1.5 6.5e-05 22.7 0.0 3.3 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) P16-Arc PF04699.14 RLN46701.1 - 0.06 13.8 0.0 0.071 13.6 0.0 1.0 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) TauD PF02668.16 RLN46735.1 - 8.9e-65 219.1 2.7 1.1e-64 218.9 2.7 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PK PF00224.21 RLN46744.1 - 2.7e-144 480.3 0.5 1e-143 478.5 0.2 1.8 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain PK_C PF02887.16 RLN46744.1 - 4.9e-27 94.5 0.1 1.3e-26 93.1 0.1 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 RLN46744.1 - 0.0003 20.0 0.2 0.00078 18.6 0.2 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family MIP PF00230.20 RLN46745.1 - 9e-11 41.9 3.8 9.3e-11 41.9 2.5 1.6 2 0 0 2 2 2 1 Major intrinsic protein UPF0242 PF06785.11 RLN46745.1 - 0.00092 19.4 0.2 0.0012 19.0 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Tup_N PF08581.10 RLN46745.1 - 0.0013 19.0 4.8 0.0013 19.0 4.8 2.2 1 1 1 2 2 2 1 Tup N-terminal Golgin_A5 PF09787.9 RLN46745.1 - 0.021 14.3 10.5 0.03 13.8 10.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Phage_tail_APC PF16778.5 RLN46745.1 - 0.44 10.4 6.8 1.9 8.5 1.5 2.5 1 1 1 2 2 2 0 Phage tail assembly chaperone protein YabA PF06156.13 RLN46745.1 - 1.4 9.6 5.5 2.4 8.8 5.5 1.4 1 0 0 1 1 1 0 Initiation control protein YabA OmpH PF03938.14 RLN46745.1 - 3.1 8.1 9.8 4.8 7.5 9.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Csm1_N PF18504.1 RLN46745.1 - 6.6 7.2 10.6 0.9 9.9 2.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain End3 PF12761.7 RLN46745.1 - 9.3 6.4 11.1 20 5.3 8.4 2.0 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 NUC173 PF08161.12 RLN46836.1 - 4e-56 189.9 0.1 4e-56 189.9 0.1 3.6 4 0 0 4 4 4 1 NUC173 domain Vac14_Fab1_bd PF12755.7 RLN46836.1 - 0.029 15.0 0.0 37 5.0 0.0 4.9 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region TAFH PF07531.14 RLN46836.1 - 3.2 7.9 5.2 2.6 8.2 0.5 3.2 3 0 0 3 3 3 0 NHR1 homology to TAF Glyco_transf_8 PF01501.20 RLN46837.1 - 1.7e-05 24.6 0.0 0.00013 21.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 RLN46837.1 - 0.023 14.1 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative WD40 PF00400.32 RLN46838.1 - 1.3e-40 136.6 24.8 1.6e-08 35.1 0.7 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN46838.1 - 9e-13 48.3 1.1 0.0044 17.3 0.0 5.8 2 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN46838.1 - 0.0002 20.4 3.9 2.1 7.2 0.0 4.3 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RLN46838.1 - 0.00067 18.4 1.8 0.6 8.7 0.1 4.6 2 1 3 6 6 6 1 Nucleoporin Nup120/160 Med3 PF11593.8 RLN46838.1 - 0.0012 18.2 3.4 0.0012 18.2 3.4 1.8 2 0 0 2 2 2 1 Mediator complex subunit 3 fungal Ribosomal_L9_N PF01281.19 RLN46838.1 - 0.13 11.8 0.1 3.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L9, N-terminal domain YabA PF06156.13 RLN46838.1 - 0.14 12.8 1.8 1 10.0 0.3 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Rab5-bind PF09311.11 RLN46838.1 - 0.22 10.9 8.1 0.31 10.4 8.1 1.1 1 0 0 1 1 1 0 Rabaptin-like protein Fib_alpha PF08702.10 RLN46838.1 - 0.25 11.5 3.8 0.45 10.7 3.8 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Cortex-I_coil PF09304.10 RLN46838.1 - 0.42 10.8 7.6 0.81 9.9 7.6 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil V_ATPase_I PF01496.19 RLN46838.1 - 1.3 6.8 2.8 1.8 6.4 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4200 PF13863.6 RLN46838.1 - 1.4 9.3 12.4 0.33 11.4 8.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) GPS2_interact PF15784.5 RLN46838.1 - 2.4 8.7 5.0 3.5 8.1 3.7 1.9 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Tropomyosin_1 PF12718.7 RLN46838.1 - 3.6 7.7 12.2 2.6 8.2 2.1 3.0 1 1 2 3 3 3 0 Tropomyosin like Herpes_capsid PF06112.11 RLN46838.1 - 4.6 7.3 18.1 0.69 10.0 10.9 2.6 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Cep57_CLD_2 PF14197.6 RLN46838.1 - 5.4 7.2 8.1 8.7 6.5 3.8 2.8 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Trypsin_2 PF13365.6 RLN46839.1 - 9e-09 36.4 0.1 1.7e-08 35.5 0.1 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain Glycos_transf_3 PF00591.21 RLN46840.1 - 0.12 11.9 1.2 0.19 11.3 1.2 1.3 1 0 0 1 1 1 0 Glycosyl transferase family, a/b domain Aldedh PF00171.22 RLN46841.1 - 1.6e-47 162.1 0.1 1.8e-47 161.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RNA_pol_Rpc4 PF05132.14 RLN46861.1 - 1e-18 68.2 1.2 2.2e-17 63.8 1.2 2.2 1 1 0 1 1 1 1 RNA polymerase III RPC4 HMG_box PF00505.19 RLN46862.1 - 8.7e-44 147.8 9.8 5.9e-22 77.9 0.9 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 RLN46862.1 - 5.9e-28 97.3 10.1 1.1e-13 51.5 1.8 2.3 2 0 0 2 2 2 2 HMG-box domain CHDNT PF08073.12 RLN46862.1 - 3.3e-05 23.8 0.0 0.018 15.0 0.0 2.4 2 0 0 2 2 2 2 CHDNT (NUC034) domain Ccdc124 PF06244.12 RLN46862.1 - 0.0041 17.7 11.6 0.02 15.4 0.3 3.1 2 1 1 3 3 3 2 Coiled-coil domain-containing protein 124 /Oxs1 DUF4838 PF16126.5 RLN46862.1 - 0.041 13.3 0.2 2.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4838) DAD PF02109.16 RLN46862.1 - 0.18 12.1 0.1 0.89 9.9 0.0 1.9 2 0 0 2 2 2 0 DAD family CNDH2_C PF16858.5 RLN46862.1 - 0.91 9.3 11.5 0.24 11.2 3.6 2.0 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CENP-B_dimeris PF09026.10 RLN46862.1 - 7.2 7.1 13.6 19 5.7 0.0 2.6 3 0 0 3 3 3 0 Centromere protein B dimerisation domain RNA_pol_Rpo13 PF12136.8 RLN46908.1 - 0.043 13.7 0.1 0.09 12.7 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain E1-E2_ATPase PF00122.20 RLN46910.1 - 2.1e-46 157.7 4.4 1.2e-30 106.4 0.5 2.4 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase PF13246.6 RLN46910.1 - 1.1e-18 67.0 0.0 1.6e-17 63.4 0.0 2.5 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 RLN46910.1 - 1e-14 53.9 0.0 2.3e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 RLN46910.1 - 1.1e-09 38.9 0.1 1.3e-05 25.6 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF998 PF06197.13 RLN46910.1 - 0.14 11.7 4.5 0.079 12.6 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF998) UPF0029 PF01205.19 RLN46914.1 - 0.049 14.0 0.8 0.16 12.3 0.8 1.8 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 Kinesin PF00225.23 RLN46915.1 - 3.1e-48 164.4 0.2 1.5e-47 162.2 0.1 1.7 1 1 1 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RLN46916.1 - 1.8e-22 79.9 0.0 9e-21 74.4 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding Kinesin PF00225.23 RLN46916.1 - 4.5e-15 55.4 0.0 6.2e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain GDH_N PF12466.8 RLN46916.1 - 0.026 14.7 3.2 0.15 12.3 0.1 2.8 2 1 1 3 3 3 0 Glutamate dehydrogenase N terminal ER_lumen_recept PF00810.18 RLN46917.1 - 1.5e-14 55.0 1.1 1.5e-14 55.0 1.1 1.8 2 0 0 2 2 2 1 ER lumen protein retaining receptor Ank_2 PF12796.7 RLN46920.1 - 6.8e-23 81.1 0.4 1.1e-11 45.2 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN46920.1 - 2.2e-20 72.4 3.6 1.6e-07 31.5 0.4 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN46920.1 - 2.2e-20 72.1 4.4 6.6e-07 29.5 0.1 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 RLN46920.1 - 5.8e-20 71.4 0.1 7.2e-08 32.8 0.1 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN46920.1 - 1.6e-15 55.6 0.6 0.0057 17.1 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat FYVE PF01363.21 RLN46920.1 - 4e-15 55.7 12.4 8.3e-15 54.7 12.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN46920.1 - 0.0033 17.6 8.1 0.0033 17.6 8.1 1.6 2 0 0 2 2 2 1 FYVE-type zinc finger ELO PF01151.18 RLN46921.1 - 1.5e-66 224.5 16.2 1.8e-66 224.2 16.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Mtc PF03820.17 RLN46922.1 - 1.1e-98 330.2 1.0 1.3e-98 329.9 1.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier CbtA PF09490.10 RLN46922.1 - 0.022 14.5 3.4 0.022 14.5 3.4 1.9 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) 2-Hacid_dh_C PF02826.19 RLN46923.1 - 2.6e-57 193.1 0.0 4.3e-57 192.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 RLN46923.1 - 2.1e-30 105.1 0.0 2.3e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 RLN46923.1 - 2.5e-06 27.7 0.0 7.4e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 RLN46923.1 - 0.0017 18.4 0.2 0.004 17.2 0.0 1.6 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 RLN46923.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 RLN46923.1 - 0.012 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN46923.1 - 0.079 12.2 0.1 2.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DSPc PF00782.20 RLN46924.1 - 7.8e-18 64.6 0.0 1.5e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RLN46924.1 - 0.037 13.6 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 RLN46924.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain 2-Hacid_dh_C PF02826.19 RLN46925.1 - 5.6e-57 192.0 0.0 9.3e-57 191.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 RLN46925.1 - 5.2e-30 103.8 0.0 6e-30 103.6 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 RLN46925.1 - 3.1e-06 27.4 0.1 1e-05 25.7 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 RLN46925.1 - 0.0011 19.1 0.6 0.0022 18.1 0.1 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 RLN46925.1 - 0.0074 16.2 0.3 0.023 14.6 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 RLN46925.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 RLN46925.1 - 0.025 13.9 0.2 2.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DNA_pol_A_exo1 PF01612.20 RLN46925.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 3'-5' exonuclease CHASE2 PF05226.11 RLN46925.1 - 0.19 11.4 0.0 0.41 10.3 0.0 1.6 1 1 0 1 1 1 0 CHASE2 domain 2-Hacid_dh_C PF02826.19 RLN46926.1 - 4.3e-56 189.1 0.0 8e-56 188.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 RLN46926.1 - 9.6e-30 103.0 0.1 1.2e-29 102.7 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 RLN46926.1 - 3.5e-06 27.3 0.2 3.2e-05 24.1 0.0 2.3 2 1 1 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 RLN46926.1 - 3.6e-05 23.9 0.1 7.4e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 RLN46926.1 - 0.00017 21.2 0.0 0.00038 20.1 0.0 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 RLN46926.1 - 0.0088 16.0 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_N PF05222.15 RLN46926.1 - 0.022 15.0 0.0 0.7 10.2 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, N-terminal domain F420_oxidored PF03807.17 RLN46926.1 - 0.041 14.5 0.2 1.3 9.6 0.1 2.7 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Putative_PNPOx PF01243.20 RLN46926.1 - 0.046 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase CoA_binding_2 PF13380.6 RLN46926.1 - 0.11 13.0 0.0 0.37 11.3 0.0 1.9 1 1 0 1 1 1 0 CoA binding domain Shikimate_DH PF01488.20 RLN46926.1 - 0.17 12.0 4.0 3.8 7.6 0.1 2.8 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DUF2039 PF10217.9 RLN46927.1 - 1.2e-16 60.8 3.1 1.8e-16 60.3 3.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) DUF536 PF04394.14 RLN46927.1 - 0.063 13.1 0.9 0.12 12.3 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF536 IR1-M PF12185.8 RLN46928.1 - 0.11 12.4 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain HPS3_N PF14761.6 RLN46929.1 - 4.7e-10 39.4 0.6 8.6e-09 35.2 0.2 2.8 2 1 0 2 2 2 1 Hermansky-Pudlak syndrome 3 HPS3_Mid PF14762.6 RLN46929.1 - 0.01 14.6 0.0 0.11 11.2 0.0 2.2 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3, middle region 7TM-7TMR_HD PF07698.11 RLN46930.1 - 0.0053 16.5 3.8 0.0053 16.5 3.8 2.0 2 1 0 2 2 2 1 7TM receptor with intracellular HD hydrolase DUF4726 PF15855.5 RLN46930.1 - 0.13 12.5 0.1 0.23 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4726) HTH_7 PF02796.15 RLN46950.1 - 0.00091 19.3 0.0 0.0013 18.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase PSP PF04046.16 RLN46950.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 PSP EF-hand_1 PF00036.32 RLN46951.1 - 0.011 15.2 0.0 0.035 13.7 0.0 1.9 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 RLN46951.1 - 0.013 16.0 0.1 0.066 13.7 0.1 2.3 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 RLN46951.1 - 0.024 14.1 0.1 0.075 12.6 0.1 1.9 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 RLN46951.1 - 0.17 11.8 0.0 0.45 10.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Glu_cyclase_2 PF05096.12 RLN46954.1 - 9.4e-82 274.2 0.0 1.2e-81 273.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase GFP PF01353.22 RLN46954.1 - 0.022 14.2 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Green fluorescent protein EF-hand_7 PF13499.6 RLN46955.1 - 9.8e-06 25.9 0.8 0.00014 22.3 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN46955.1 - 0.0021 17.5 0.1 3.4 7.4 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RLN46955.1 - 0.0028 17.4 0.0 1.9 8.6 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 RLN46955.1 - 0.055 13.3 0.1 0.75 9.7 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain pair SPC25 PF06703.11 RLN46955.1 - 1.2 9.0 2.9 16 5.2 2.5 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) NAD_binding_6 PF08030.12 RLN46956.1 - 6.4e-28 97.8 0.1 7.7e-28 97.6 0.1 1.0 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DDE_Tnp_4 PF13359.6 RLN46981.1 - 1e-20 74.0 0.0 2.7e-20 72.6 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 RLN46981.1 - 0.0027 17.3 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 RLN46981.1 - 0.019 14.6 0.0 0.1 12.3 0.0 2.0 1 1 0 1 1 1 0 Transposase DDE domain Annexin PF00191.20 RLN46985.1 - 3e-53 177.8 0.5 3.8e-13 49.3 0.0 4.1 4 0 0 4 4 4 4 Annexin DNA_ligase_A_N PF04675.14 RLN46985.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 DNA ligase N terminus DUF3848 PF12959.7 RLN46985.1 - 0.12 12.5 0.1 12 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) Annexin PF00191.20 RLN46986.1 - 7.9e-67 221.3 3.0 2.1e-17 62.9 0.0 4.2 4 0 0 4 4 4 4 Annexin baeRF_family12 PF18856.1 RLN46986.1 - 0.043 14.4 0.2 6.3 7.4 0.0 2.8 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 12 DUF3848 PF12959.7 RLN46986.1 - 0.056 13.5 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) BT1 PF03092.16 RLN46987.1 - 3e-73 246.9 19.3 1.2e-41 142.6 7.9 2.5 1 1 2 3 3 3 2 BT1 family PUCC PF03209.15 RLN46987.1 - 0.00028 20.0 1.7 0.00028 20.0 1.7 1.8 2 0 0 2 2 2 1 PUCC protein DUF1772 PF08592.11 RLN46987.1 - 0.21 11.9 0.1 0.21 11.9 0.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) PKD_channel PF08016.12 RLN46988.1 - 3.7e-09 35.8 5.4 5.3e-09 35.3 5.4 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 RLN46988.1 - 0.00022 20.6 9.5 0.00035 19.9 9.5 1.3 1 0 0 1 1 1 1 Ion transport protein PhoLip_ATPase_C PF16212.5 RLN46995.1 - 2.6e-73 246.8 24.3 2.6e-73 246.8 24.3 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RLN46995.1 - 1.8e-19 69.2 0.8 1.8e-19 69.2 0.8 1.8 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RLN46995.1 - 3.7e-11 43.7 0.1 1.7e-05 25.2 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN46995.1 - 5e-09 36.1 0.0 3.2e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RLN46995.1 - 2.1e-05 24.1 0.0 6.2e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RLN46995.1 - 0.003 17.3 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DDE_3 PF13358.6 RLN47036.1 - 8.3e-18 64.5 0.0 8.1e-17 61.3 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 RLN47036.1 - 0.00032 21.2 0.2 0.014 16.0 0.0 2.6 2 1 1 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.6 RLN47036.1 - 0.0078 16.0 0.3 0.021 14.6 0.3 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 RLN47036.1 - 0.013 14.8 0.3 0.22 11.0 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 FCD PF07729.12 RLN47036.1 - 0.044 14.2 0.5 0.13 12.7 0.5 1.9 1 0 0 1 1 1 0 FCD domain Pkinase_Tyr PF07714.17 RLN47057.1 - 2.1e-68 230.4 0.0 3.1e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN47057.1 - 4.4e-58 196.7 0.0 6.2e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RLN47057.1 - 0.00071 19.0 0.0 0.0016 17.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 RLN47057.1 - 0.0015 17.5 0.0 0.0028 16.7 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 RLN47057.1 - 0.012 14.5 0.1 0.028 13.2 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 RLN47057.1 - 0.24 11.3 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Arm PF00514.23 RLN47061.1 - 3.5e-46 153.9 16.7 2.1e-06 27.6 0.3 12.3 13 0 0 13 13 13 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN47061.1 - 1.4e-12 47.8 25.2 0.021 15.3 0.2 8.1 5 2 3 8 8 8 7 HEAT-like repeat V-ATPase_H_N PF03224.14 RLN47061.1 - 9.5e-09 35.0 0.0 0.00051 19.4 0.0 3.6 1 1 1 3 3 3 2 V-ATPase subunit H UNC45-central PF11701.8 RLN47061.1 - 4e-07 30.1 1.6 2.4 8.1 0.2 4.6 4 0 0 4 4 4 3 Myosin-binding striated muscle assembly central HEAT_2 PF13646.6 RLN47061.1 - 1.2e-06 28.8 34.4 0.0068 16.8 0.9 7.0 2 2 7 9 9 9 6 HEAT repeats HEAT PF02985.22 RLN47061.1 - 7.8e-06 25.7 13.3 4.4 7.8 0.1 10.0 12 0 0 12 12 12 1 HEAT repeat Arm_2 PF04826.13 RLN47061.1 - 0.0004 19.9 0.0 0.036 13.5 0.0 3.4 2 1 1 3 3 3 1 Armadillo-like Atx10homo_assoc PF09759.9 RLN47061.1 - 0.00058 19.8 0.5 5.7 7.0 0.1 4.5 4 2 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 RLN47061.1 - 0.0012 19.3 51.9 0.92 10.4 0.2 12.2 13 1 0 13 13 13 2 PBS lyase HEAT-like repeat Tex_N PF09371.10 RLN47061.1 - 4.9 6.8 6.5 12 5.5 0.0 3.4 3 1 1 4 4 4 0 Tex-like protein N-terminal domain LmjF365940-deam PF14421.6 RLN47067.1 - 0.017 14.7 0.0 0.044 13.4 0.0 1.7 2 0 0 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Polo_box_2 PF18531.1 RLN47067.1 - 0.056 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Polo box domain EF-hand_7 PF13499.6 RLN47069.1 - 4e-10 40.0 0.3 3.2e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN47069.1 - 5.2e-10 38.1 0.0 0.0054 16.2 0.2 3.5 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 RLN47069.1 - 8.4e-08 31.4 0.3 0.083 12.4 0.1 3.6 3 0 0 3 3 3 3 EF hand WD40 PF00400.32 RLN47069.1 - 2.1e-07 31.5 11.4 3 8.9 0.0 7.1 8 0 0 8 8 8 4 WD domain, G-beta repeat EF-hand_6 PF13405.6 RLN47069.1 - 2.5e-07 30.1 0.1 0.47 10.5 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 RLN47069.1 - 0.004 17.0 2.0 2.2 8.2 0.5 3.4 2 1 1 3 3 3 1 EF-hand domain pair Nucleoside_tran PF01733.18 RLN47072.1 - 7.9e-27 94.4 18.1 7.9e-27 94.4 18.1 2.4 2 1 0 2 2 2 1 Nucleoside transporter Tudor_2 PF18104.1 RLN47072.1 - 0.071 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain MFS_1 PF07690.16 RLN47072.1 - 0.099 11.5 47.4 0.49 9.3 11.9 3.2 1 1 2 3 3 3 0 Major Facilitator Superfamily DUF202 PF02656.15 RLN47072.1 - 6 7.4 12.7 12 6.5 2.6 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Ufd2P_core PF10408.9 RLN47073.1 - 7.3e-25 87.6 0.0 4.9e-19 68.4 0.0 2.8 3 1 0 3 3 3 2 Ubiquitin elongating factor core ZZ PF00569.17 RLN47073.1 - 1.1e-07 31.5 27.8 1.2e-06 28.3 10.6 3.7 3 0 0 3 3 3 2 Zinc finger, ZZ type C1_2 PF03107.16 RLN47073.1 - 0.00051 20.3 2.0 0.00051 20.3 2.0 3.4 3 0 0 3 3 3 1 C1 domain Ead_Ea22 PF13935.6 RLN47073.1 - 0.044 14.5 0.1 0.17 12.6 0.1 2.0 1 0 0 1 1 1 0 Ead/Ea22-like protein Nucleoside_tran PF01733.18 RLN47074.1 - 2.1e-22 79.9 5.3 2.6e-22 79.6 5.3 1.0 1 0 0 1 1 1 1 Nucleoside transporter Sugar_tr PF00083.24 RLN47104.1 - 2.5e-52 178.2 27.6 3.9e-52 177.6 27.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN47104.1 - 1.4e-30 106.4 50.2 1.2e-25 90.2 30.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 RLN47104.1 - 2.8e-06 26.9 7.5 2.8e-06 26.9 7.5 2.0 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB PAN_4 PF14295.6 RLN47114.1 - 1.1e-05 25.2 5.0 2.1e-05 24.3 5.0 1.5 1 0 0 1 1 1 1 PAN domain CAP PF00188.26 RLN47114.1 - 0.00019 22.3 0.0 0.00036 21.4 0.0 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Nop16 PF09420.10 RLN47115.1 - 4.3e-22 79.2 7.3 2.6e-14 53.8 1.1 2.1 1 1 0 2 2 2 2 Ribosome biogenesis protein Nop16 Mur_ligase_M PF08245.12 RLN47116.1 - 3.4e-05 23.9 0.0 0.00029 20.9 0.0 2.5 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 RLN47116.1 - 0.0014 18.8 0.0 0.004 17.4 0.0 1.8 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain GTP_EFTU PF00009.27 RLN47117.1 - 1.2e-52 178.3 0.0 2e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 RLN47117.1 - 6.3e-42 142.4 0.1 1.2e-41 141.5 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 RLN47117.1 - 3.7e-12 46.5 1.1 8.3e-12 45.3 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RLN47117.1 - 0.00018 21.6 0.0 0.037 14.1 0.0 2.5 2 1 0 2 2 2 2 50S ribosome-binding GTPase FlpD PF02662.16 RLN47117.1 - 0.022 14.8 0.0 0.29 11.1 0.0 2.2 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit GTP_EFTU_D4 PF14578.6 RLN47117.1 - 0.05 13.5 0.1 0.18 11.7 0.1 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 DLH PF01738.18 RLN47118.1 - 2.2e-17 63.3 0.8 2.8e-17 63.0 0.8 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF357 PF04010.13 RLN47118.1 - 0.054 13.6 0.1 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF357) Hydrolase_4 PF12146.8 RLN47118.1 - 0.077 12.2 0.0 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Na_H_Exchanger PF00999.21 RLN47119.1 - 2.6e-12 46.2 25.9 2.6e-12 46.2 25.9 2.0 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family TFIID_20kDa PF03847.13 RLN47119.1 - 0.18 12.3 0.7 8.6 6.9 0.2 2.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Ank_2 PF12796.7 RLN47122.1 - 2e-33 114.8 9.2 2.2e-07 31.4 0.0 6.9 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN47122.1 - 4.1e-30 103.8 16.7 2.4e-05 24.8 0.2 10.0 5 3 4 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN47122.1 - 1.9e-20 72.7 21.3 0.018 15.3 0.0 12.3 6 3 7 13 13 13 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN47122.1 - 1.1e-18 65.4 8.4 1.6 9.5 0.0 13.4 14 0 0 14 14 14 3 Ankyrin repeat Ank PF00023.30 RLN47122.1 - 1.9e-06 28.1 6.0 13 6.5 0.0 8.3 8 1 1 9 9 9 2 Ankyrin repeat Methyltransf_32 PF13679.6 RLN47122.1 - 0.034 14.1 0.1 0.092 12.7 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain Ank_2 PF12796.7 RLN47123.1 - 1e-27 96.5 23.3 7.8e-09 36.0 0.3 5.7 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN47123.1 - 7e-25 87.1 22.2 1.9e-05 25.1 0.4 8.4 6 2 3 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN47123.1 - 7.4e-18 64.4 26.4 0.0099 16.2 0.1 11.2 5 2 5 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN47123.1 - 8.9e-14 50.3 16.0 1.7 9.5 0.1 11.2 11 1 1 12 12 12 4 Ankyrin repeat Ank PF00023.30 RLN47123.1 - 0.00029 21.1 6.9 13 6.4 0.0 7.8 8 1 0 8 8 8 1 Ankyrin repeat Ank_2 PF12796.7 RLN47124.1 - 5.4e-12 46.1 0.4 5.1e-05 23.8 0.3 3.6 3 2 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN47124.1 - 1.2e-09 38.5 3.9 0.0087 16.6 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN47124.1 - 5.9e-09 36.0 2.0 0.27 11.6 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN47124.1 - 3.8e-07 29.9 4.4 2 9.2 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 RLN47124.1 - 0.044 14.2 1.7 85 3.9 0.0 4.8 6 0 0 6 6 6 0 Ankyrin repeat Peptidase_C48 PF02902.19 RLN47128.1 - 5e-15 55.9 0.0 5.8e-14 52.4 0.0 2.4 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain U1snRNP70_N PF12220.8 RLN47128.1 - 1.6 9.4 6.8 26 5.6 1.9 2.9 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF789 PF05623.12 RLN47128.1 - 5.5 6.6 6.8 5.6 6.6 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF789) F-box PF00646.33 RLN47129.1 - 0.014 15.3 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 F-box domain LOB PF03195.14 RLN47129.1 - 0.072 13.7 0.3 0.42 11.2 0.0 2.4 2 0 0 2 2 2 0 Lateral organ boundaries (LOB) domain Mce4_CUP1 PF11887.8 RLN47129.1 - 1.6 8.1 5.0 3.4 7.1 1.2 2.7 1 1 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Pkinase PF00069.25 RLN47130.1 - 2.4e-66 223.8 0.0 3.5e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN47130.1 - 5e-36 124.3 0.0 8e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN47130.1 - 1.5e-05 24.0 0.0 3.4e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase PH PF00169.29 RLN47130.1 - 0.0001 22.8 0.0 0.028 14.9 0.0 2.5 2 0 0 2 2 2 1 PH domain APH PF01636.23 RLN47130.1 - 0.0028 17.6 0.8 0.025 14.5 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 RLN47130.1 - 0.0083 15.7 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family PH_11 PF15413.6 RLN47130.1 - 0.012 16.0 0.0 0.032 14.7 0.0 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain Kdo PF06293.14 RLN47130.1 - 0.028 13.8 0.1 0.052 12.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1_like PF12832.7 RLN47132.1 - 5.6e-64 216.4 15.2 9.4e-64 215.6 15.2 1.3 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RLN47132.1 - 7.3e-20 71.2 29.1 1.7e-19 70.0 25.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 RLN47132.1 - 1.2e-14 53.9 11.9 3.1e-14 52.6 11.9 1.6 1 1 0 1 1 1 1 LacY proton/sugar symporter Nuc_H_symport PF03825.16 RLN47132.1 - 7.5e-12 44.9 12.0 3e-11 42.9 12.0 1.7 1 1 0 1 1 1 1 Nucleoside H+ symporter MFS_2 PF13347.6 RLN47132.1 - 5.6e-07 28.5 18.4 1.1e-06 27.5 16.1 2.2 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_3 PF05977.13 RLN47132.1 - 0.024 13.1 10.9 0.049 12.0 10.9 1.4 1 1 0 1 1 1 0 Transmembrane secretion effector MIP PF00230.20 RLN47151.1 - 1.9e-101 338.5 16.6 7.2e-51 173.1 4.2 2.5 3 0 0 3 3 3 2 Major intrinsic protein Tup_N PF08581.10 RLN47151.1 - 0.00081 19.7 1.3 0.00081 19.7 1.3 2.2 2 0 0 2 2 2 1 Tup N-terminal UPF0242 PF06785.11 RLN47151.1 - 0.012 15.7 0.1 0.02 15.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Phage_holin_5_2 PF16079.5 RLN47151.1 - 0.017 15.4 1.8 12 6.3 0.0 3.6 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V CPBP PF02517.16 RLN47151.1 - 0.38 11.2 4.1 17 5.9 0.6 3.0 2 2 0 2 2 2 0 CPBP intramembrane metalloprotease FUSC PF04632.12 RLN47151.1 - 0.72 8.3 11.4 1.9 6.9 11.4 1.6 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6_N PF17675.1 RLN47151.1 - 0.76 10.3 13.2 1.1 9.8 13.2 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Golgin_A5 PF09787.9 RLN47151.1 - 1.3 8.4 11.0 2 7.8 11.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 XK-related PF09815.9 RLN47151.1 - 1.7 7.6 6.3 5.8 5.9 0.6 2.3 2 0 0 2 2 2 0 XK-related protein Phage_tail_APC PF16778.5 RLN47151.1 - 2.6 8.0 6.5 6 6.8 4.0 2.6 1 1 1 2 2 2 0 Phage tail assembly chaperone protein Med9 PF07544.13 RLN47151.1 - 9.9 6.3 6.6 34 4.6 6.6 1.8 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 PK PF00224.21 RLN47152.1 - 4.1e-145 483.0 0.4 1.7e-144 481.0 0.2 1.8 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain PK_C PF02887.16 RLN47152.1 - 5e-27 94.5 0.1 1.3e-26 93.1 0.1 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 RLN47152.1 - 0.00033 19.9 0.1 0.00077 18.7 0.1 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family TrkA_N PF02254.18 RLN47169.1 - 0.13 12.5 0.0 0.45 10.8 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 RLN47169.1 - 0.2 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_3 PF07859.13 RLN47170.1 - 7.5e-21 75.0 0.2 1.3e-19 70.9 0.2 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 RLN47170.1 - 3.1e-16 59.3 1.3 8.2e-16 58.0 1.3 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 RLN47170.1 - 9.3e-08 32.9 1.1 1.6e-07 32.2 1.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 RLN47170.1 - 0.00086 18.8 0.1 0.013 15.0 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 RLN47170.1 - 0.0027 17.4 0.7 0.046 13.4 0.3 2.5 2 1 0 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN47170.1 - 0.0032 16.8 0.5 0.021 14.1 0.1 2.4 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 RLN47170.1 - 0.0046 15.9 0.0 0.0088 15.0 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF829 PF05705.14 RLN47170.1 - 0.013 15.5 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Esterase PF00756.20 RLN47170.1 - 0.021 14.4 0.6 0.41 10.3 0.6 2.2 1 1 0 1 1 1 0 Putative esterase Tombus_movement PF05318.12 RLN47170.1 - 8.8 7.2 8.2 10 7.1 1.5 3.2 3 0 0 3 3 3 0 Tombusvirus movement protein DLH PF01738.18 RLN47171.1 - 7.4e-17 61.6 0.2 1.3e-16 60.9 0.2 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 RLN47171.1 - 0.0057 15.9 0.0 0.22 10.8 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Methyltransf_15 PF09445.10 RLN47172.1 - 1.7e-16 60.3 0.0 2.8e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 RLN47172.1 - 0.0002 21.1 0.0 0.0004 20.1 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltr_RsmB-F PF01189.17 RLN47172.1 - 0.048 13.3 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DUF4698 PF15769.5 RLN47172.1 - 7.2 5.5 11.1 2.1 7.3 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4698) LPG_synthase_TM PF03706.13 RLN47173.1 - 0.0061 16.1 2.0 0.0077 15.8 2.0 1.1 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region Podoplanin PF05808.11 RLN47173.1 - 0.023 14.8 0.9 0.028 14.5 0.9 1.2 1 0 0 1 1 1 0 Podoplanin DUF4366 PF14283.6 RLN47173.1 - 0.19 11.8 1.6 0.16 12.0 0.5 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) DUF515 PF04415.12 RLN47173.1 - 0.28 9.5 4.9 0.3 9.4 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Defensin_propep PF00879.18 RLN47173.1 - 0.29 11.4 2.7 0.63 10.4 2.7 1.7 1 0 0 1 1 1 0 Defensin propeptide Phage_holin_2_4 PF16082.5 RLN47173.1 - 0.35 10.6 6.9 0.32 10.8 3.0 2.3 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like stn_TNFRSF12A PF12191.8 RLN47173.1 - 0.5 10.6 2.4 0.44 10.8 0.7 1.7 1 1 1 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain G-patch PF01585.23 RLN47175.1 - 7.2e-09 35.4 2.4 7.2e-09 35.4 2.4 2.3 3 0 0 3 3 3 1 G-patch domain zf-C2H2_jaz PF12171.8 RLN47175.1 - 6.8e-06 26.2 3.8 1.4e-05 25.2 3.8 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RLN47175.1 - 0.0011 19.3 0.7 0.0019 18.5 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 RLN47175.1 - 0.01 15.9 4.1 0.019 15.1 4.1 1.4 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_2 PF12756.7 RLN47175.1 - 0.026 14.8 1.9 0.044 14.1 1.9 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 RLN47175.1 - 0.08 13.8 0.4 0.19 12.6 0.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger G-patch_2 PF12656.7 RLN47175.1 - 0.31 11.1 0.1 0.31 11.1 0.1 2.3 3 0 0 3 3 3 0 G-patch domain SAE2 PF08573.10 RLN47175.1 - 1.1 10.4 13.3 0.43 11.7 9.3 2.1 1 1 1 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF4551 PF15087.6 RLN47175.1 - 1.4 7.7 7.4 1.8 7.3 7.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Glyco_tran_28_C PF04101.16 RLN47191.1 - 1.3e-22 80.6 0.0 1.6e-22 80.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Pyr_redox_2 PF07992.14 RLN47192.1 - 2.2e-47 161.7 1.9 1.4e-46 159.1 0.4 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 RLN47192.1 - 1.2e-24 86.7 1.0 4.7e-24 84.8 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 RLN47192.1 - 6.2e-17 61.9 1.5 1.6e-12 47.8 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RLN47192.1 - 1.2e-07 31.9 0.4 0.00015 21.9 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 RLN47192.1 - 2.7e-07 30.3 0.0 4.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 RLN47192.1 - 2.9e-07 30.1 0.0 0.0086 15.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 RLN47192.1 - 1.5e-05 24.3 0.8 1.5e-05 24.3 0.8 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 RLN47192.1 - 3.6e-05 22.7 4.8 0.00036 19.3 0.2 2.9 2 1 1 3 3 3 1 HI0933-like protein Thi4 PF01946.17 RLN47192.1 - 3.9e-05 23.0 0.2 0.001 18.4 0.0 2.3 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.18 RLN47192.1 - 0.00013 21.9 0.1 0.02 14.8 0.0 2.9 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN47192.1 - 0.0033 16.8 0.4 0.36 10.1 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 RLN47192.1 - 0.0067 15.5 0.9 1.7 7.6 0.3 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 RLN47192.1 - 0.017 14.7 8.1 0.063 12.9 0.1 3.4 3 1 1 4 4 4 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 RLN47192.1 - 0.02 14.0 0.0 3.7 6.6 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 RLN47192.1 - 0.16 11.0 2.8 0.19 10.7 0.1 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A DUF4598 PF15370.6 RLN47194.1 - 1.4e-10 41.6 3.9 5.3e-10 39.8 3.9 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4598) COX4 PF02936.14 RLN47194.1 - 0.00012 22.1 0.0 0.00039 20.4 0.0 1.7 2 0 0 2 2 2 1 Cytochrome c oxidase subunit IV Isy1 PF06246.12 RLN47195.1 - 4.2e-67 226.4 2.2 7.4e-66 222.3 2.3 2.0 1 1 0 1 1 1 1 Isy1-like splicing family Paramyxo_C PF01692.18 RLN47195.1 - 0.055 12.8 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Paramyxovirus non-structural protein C DUF5617 PF18493.1 RLN47195.1 - 0.088 12.9 0.4 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) Ank_2 PF12796.7 RLN47197.1 - 1.6e-10 41.4 0.0 0.00048 20.7 0.0 4.5 2 1 4 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN47197.1 - 1.8e-07 31.6 3.9 0.008 16.7 0.0 5.3 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN47197.1 - 1.3e-05 25.3 3.0 0.2 12.0 0.0 4.6 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN47197.1 - 0.00014 22.0 3.4 0.82 10.4 0.0 5.6 5 1 1 6 6 6 1 Ankyrin repeat Ank PF00023.30 RLN47197.1 - 0.00046 20.5 0.2 4.7 7.8 0.1 4.7 4 0 0 4 4 4 1 Ankyrin repeat Ion_trans PF00520.31 RLN47197.1 - 0.28 10.4 17.9 0.84 8.8 17.7 1.9 1 1 0 1 1 1 0 Ion transport protein WWE PF02825.20 RLN47198.1 - 0.052 14.1 0.1 2 9.0 0.0 2.7 2 0 0 2 2 2 0 WWE domain Mto2_bdg PF12808.7 RLN47199.1 - 0.97 9.8 8.6 8.2 6.8 0.4 3.4 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region STAT_int PF02865.17 RLN47199.1 - 5.2 7.6 11.9 0.15 12.5 3.6 2.3 3 0 0 3 3 3 0 STAT protein, protein interaction domain Sas6_CC PF18594.1 RLN47199.1 - 8.2 6.3 10.9 31 4.5 0.1 3.9 4 0 0 4 4 4 0 Sas6/XLF/XRCC4 coiled-coil domain polyprenyl_synt PF00348.17 RLN47200.1 - 6e-58 195.9 0.0 1.7e-51 174.8 0.0 2.2 2 0 0 2 2 2 2 Polyprenyl synthetase FGE-sulfatase PF03781.16 RLN47201.1 - 2.3e-21 76.6 0.7 3.8e-21 75.9 0.7 1.4 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 RLN47201.1 - 5.5e-07 30.1 0.1 1.3e-06 29.0 0.1 1.7 1 0 0 1 1 1 1 DinB superfamily NAD_binding_10 PF13460.6 RLN47202.1 - 1e-14 54.9 4.1 2e-11 44.2 2.5 2.8 3 0 0 3 3 3 2 NAD(P)H-binding NmrA PF05368.13 RLN47202.1 - 1.1e-12 48.1 0.1 1e-07 31.8 0.9 3.2 3 0 0 3 3 3 2 NmrA-like family DapB_N PF01113.20 RLN47202.1 - 0.032 14.4 0.1 0.086 13.0 0.1 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 RLN47202.1 - 0.059 12.8 0.8 0.27 10.7 0.2 2.1 2 0 0 2 2 2 0 short chain dehydrogenase UCR_14kD PF02271.16 RLN47202.1 - 0.24 11.4 1.0 6 6.9 0.1 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Metallopep PF12044.8 RLN47203.1 - 2.8e-17 62.5 0.0 5.2e-09 35.2 0.0 2.3 2 0 0 2 2 2 2 Putative peptidase family Jacalin PF01419.17 RLN47203.1 - 6.2e-14 52.1 0.0 6.3e-06 26.2 0.0 2.4 2 0 0 2 2 2 2 Jacalin-like lectin domain Pkinase_Tyr PF07714.17 RLN47204.1 - 3.8e-46 157.5 0.0 3e-40 138.1 0.0 3.5 3 1 1 4 4 4 2 Protein tyrosine kinase Pkinase PF00069.25 RLN47204.1 - 1.6e-41 142.5 0.0 4e-38 131.3 0.0 3.8 3 1 0 3 3 3 1 Protein kinase domain DUF5129 PF17173.4 RLN47204.1 - 4.6e-05 22.7 0.4 0.00011 21.4 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5129) APH PF01636.23 RLN47204.1 - 0.0045 16.9 0.1 0.0045 16.9 0.1 3.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family EzrA PF06160.12 RLN47204.1 - 0.0045 15.2 2.5 0.0074 14.5 2.5 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF1090 PF06476.12 RLN47204.1 - 0.012 15.7 1.4 0.031 14.4 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) Ribosomal_S7e PF01251.18 RLN47204.1 - 0.087 12.6 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S7e DUF2408 PF10303.9 RLN47204.1 - 1 9.9 4.2 2.4 8.7 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Syntaxin-6_N PF09177.11 RLN47204.1 - 5.4 7.6 7.1 3.4 8.3 0.9 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Dynein_light PF01221.18 RLN47205.1 - 6.1e-24 84.2 0.1 9.7e-24 83.5 0.1 1.3 1 1 0 1 1 1 1 Dynein light chain type 1 Na_H_Exchanger PF00999.21 RLN47206.1 - 4.4e-20 71.8 29.4 6.5e-20 71.3 29.4 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SBF PF01758.16 RLN47206.1 - 0.00088 19.0 5.4 0.00088 19.0 5.4 2.4 3 0 0 3 3 3 1 Sodium Bile acid symporter family Metallophos PF00149.28 RLN47208.1 - 2.9e-09 37.7 0.1 4.2e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ABC2_membrane PF01061.24 RLN47221.1 - 1.5e-31 109.4 24.7 2e-31 109.1 24.7 1.1 1 0 0 1 1 1 1 ABC-2 type transporter AOX PF01786.17 RLN47222.1 - 2e-92 308.6 0.0 2.6e-92 308.3 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 RLN47222.1 - 0.061 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 MAPEG PF01124.18 RLN47223.1 - 2.3e-15 56.6 0.0 2.5e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 MAPEG family DEAD PF00270.29 RLN47246.1 - 1.7e-07 31.2 1.2 3.5e-07 30.2 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase XPG_I PF00867.18 RLN47246.1 - 2.5e-06 27.8 0.0 6.2e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 XPG I-region AAA_22 PF13401.6 RLN47246.1 - 0.00011 22.5 0.1 0.0039 17.5 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_11 PF13086.6 RLN47246.1 - 0.00016 21.5 0.3 0.00037 20.4 0.1 1.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 RLN47246.1 - 0.0038 17.2 0.0 0.03 14.2 0.0 2.5 3 0 0 3 3 3 1 NACHT domain TniB PF05621.11 RLN47246.1 - 0.019 14.4 0.0 8.1 5.8 0.0 2.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 RLN47246.1 - 0.02 15.3 0.0 0.39 11.1 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain DUF5572 PF17733.1 RLN47246.1 - 0.037 13.9 0.1 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5572) Viral_helicase1 PF01443.18 RLN47246.1 - 0.047 13.4 0.0 1.3 8.8 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 RLN47246.1 - 0.055 13.2 0.4 1.5 8.5 0.0 3.0 4 0 0 4 4 4 0 AAA domain CSD2 PF17876.1 RLN47246.1 - 0.056 13.6 0.0 24 5.2 0.0 2.9 2 0 0 2 2 2 0 Cold shock domain XPG_N PF00752.17 RLN47246.1 - 0.078 13.5 0.0 0.42 11.1 0.0 2.2 2 0 0 2 2 2 0 XPG N-terminal domain Amidohydro_1 PF01979.20 RLN47247.1 - 3.6e-55 187.7 0.0 4.2e-55 187.4 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 RLN47247.1 - 5.2e-10 39.4 0.5 6.2e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family DAHP_synth_1 PF00793.20 RLN47251.1 - 5.6e-95 317.3 0.0 6.9e-95 317.0 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family acVLRF1 PF18859.1 RLN47251.1 - 0.095 13.0 0.2 0.23 11.8 0.2 1.6 1 0 0 1 1 1 0 Actinobacteria/chloroflexi VLRF1 release factor LRAT PF04970.13 RLN47252.1 - 2.6e-20 73.0 0.1 1.4e-09 38.3 0.0 3.2 2 1 0 2 2 2 2 Lecithin retinol acyltransferase Wbp11 PF09429.10 RLN47252.1 - 0.0013 19.1 0.5 2.7 8.5 0.1 2.4 2 0 0 2 2 2 2 WW domain binding protein 11 FliG_N PF14842.6 RLN47252.1 - 0.0021 18.6 0.5 2.3 8.8 0.1 2.7 2 1 0 2 2 2 2 FliG N-terminal domain Ribosomal_S25 PF03297.15 RLN47252.1 - 0.0056 16.9 0.4 0.22 11.7 0.1 2.3 2 0 0 2 2 2 1 S25 ribosomal protein DUF1907 PF08925.11 RLN47252.1 - 0.051 13.0 0.0 4.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1907) GreA_GreB_N PF03449.15 RLN47252.1 - 0.081 13.1 1.7 6.8 6.9 0.2 2.7 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal P21-Arc PF04062.14 RLN47253.1 - 2.2e-51 174.3 0.3 2.4e-35 122.1 0.0 2.0 1 1 1 2 2 2 2 ARP2/3 complex ARPC3 (21 kDa) subunit DAGAT PF03982.13 RLN47254.1 - 8.3e-33 113.6 0.0 1.3e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase MSC PF09402.10 RLN47254.1 - 4.3e-10 39.6 0.0 1.5e-09 37.8 0.0 1.8 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain DUF4407 PF14362.6 RLN47254.1 - 0.048 13.0 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Membralin PF09746.9 RLN47255.1 - 0.21 10.6 18.3 0.12 11.4 11.0 2.2 2 0 0 2 2 2 0 Tumour-associated protein Coatomer_E PF04733.14 RLN47258.1 - 3.1e-77 259.9 0.3 3.4e-77 259.7 0.3 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_16 PF13432.6 RLN47258.1 - 6.2e-05 23.6 5.2 0.013 16.2 1.2 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN47258.1 - 7.1e-05 23.2 5.7 0.15 12.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN47258.1 - 0.00073 19.5 3.8 0.015 15.4 0.8 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN47258.1 - 0.0011 19.6 5.9 0.054 14.3 0.5 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN47258.1 - 0.011 15.6 1.1 0.36 10.7 0.5 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN47258.1 - 0.056 13.8 5.7 0.57 10.5 0.2 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat ADH_N PF08240.12 RLN47259.1 - 9.9e-15 54.4 3.6 1.4e-14 53.9 0.5 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN47259.1 - 7e-12 45.5 0.0 1.2e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 RLN47259.1 - 0.015 15.5 0.0 0.032 14.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 RLN47259.1 - 0.048 13.9 0.0 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_11 PF08241.12 RLN47259.1 - 0.14 12.8 0.0 0.29 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CUE PF02845.16 RLN47260.1 - 3.7e-10 39.3 1.9 1.9e-08 33.9 0.0 3.0 3 0 0 3 3 3 1 CUE domain zf-RING_2 PF13639.6 RLN47260.1 - 3.4e-05 24.1 8.0 7.3e-05 23.0 2.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 RLN47260.1 - 7.8e-05 22.6 5.1 0.0001 22.3 1.6 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RLN47260.1 - 9.8e-05 22.1 2.5 9.8e-05 22.1 2.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN47260.1 - 0.0003 20.4 1.6 0.0003 20.4 1.6 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RLN47260.1 - 0.008 16.0 4.3 0.008 16.0 4.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN47260.1 - 0.047 13.6 7.2 2 8.3 3.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Fibrillarin PF01269.17 RLN47260.1 - 0.064 12.4 0.3 0.099 11.7 0.3 1.2 1 0 0 1 1 1 0 Fibrillarin zf-RING_5 PF14634.6 RLN47260.1 - 0.22 11.5 8.8 3.3 7.8 8.8 2.4 1 1 0 1 1 1 0 zinc-RING finger domain Zf_RING PF16744.5 RLN47260.1 - 0.54 10.4 2.1 1.4 9.1 0.5 2.2 2 0 0 2 2 2 0 KIAA1045 RING finger zf-rbx1 PF12678.7 RLN47260.1 - 3.7 7.9 8.9 4.2 7.7 4.6 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 RLN47260.1 - 5.8 6.9 8.3 2.5 8.0 0.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DAGAT PF03982.13 RLN47261.1 - 1.1e-32 113.2 0.2 5.6e-32 110.8 0.0 2.0 2 1 0 2 2 2 1 Diacylglycerol acyltransferase LNS2 PF08235.13 RLN47262.1 - 1.1e-62 211.5 0.0 1.4e-62 211.1 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 RLN47262.1 - 6e-23 80.7 0.5 6.6e-21 74.2 0.4 2.9 2 1 0 2 2 2 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 RLN47262.1 - 4.2e-08 33.3 0.0 1.1e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain IQ PF00612.27 RLN47263.1 - 4.2e-10 38.5 23.2 0.064 13.1 0.5 6.7 6 0 0 6 6 6 5 IQ calmodulin-binding motif TPR_1 PF00515.28 RLN47263.1 - 0.00091 18.9 4.5 0.0033 17.2 1.4 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN47263.1 - 0.002 18.4 4.2 0.025 14.9 0.2 3.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN47263.1 - 0.0082 16.2 1.5 0.12 12.6 1.2 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Hs1pro-1_N PF07231.12 RLN47263.1 - 0.04 13.7 0.4 0.04 13.7 0.4 2.2 2 0 0 2 2 2 0 Hs1pro-1 N-terminus CBFD_NFYB_HMF PF00808.23 RLN47263.1 - 0.041 14.2 1.0 1.3 9.4 0.3 3.2 2 1 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TPR_10 PF13374.6 RLN47263.1 - 0.049 13.5 0.1 0.049 13.5 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 RLN47263.1 - 0.058 13.6 3.4 0.39 11.1 1.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat IQ PF00612.27 RLN47264.1 - 0.0063 16.2 0.6 0.0063 16.2 0.6 2.1 2 0 0 2 2 2 1 IQ calmodulin-binding motif Ank_2 PF12796.7 RLN47265.1 - 3.5e-24 85.2 0.0 1.5e-08 35.1 0.0 4.8 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN47265.1 - 7.8e-22 77.1 0.6 9e-07 29.1 0.1 5.2 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN47265.1 - 1.2e-17 64.0 1.1 2e-05 25.1 0.0 5.6 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN47265.1 - 2e-16 58.4 2.3 0.31 11.7 0.0 7.3 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 RLN47265.1 - 2.9e-13 49.6 4.5 0.0038 17.6 0.1 6.7 7 0 0 7 7 7 4 Ankyrin repeat IQ PF00612.27 RLN47265.1 - 0.019 14.7 49.2 0.05 13.4 1.2 9.0 8 0 0 8 8 8 0 IQ calmodulin-binding motif DUF2016 PF09436.10 RLN47265.1 - 0.28 11.0 2.5 0.99 9.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF2016) RCC1 PF00415.18 RLN47266.1 - 5.4e-102 334.3 37.7 1.1e-12 48.3 0.1 13.1 12 2 0 12 12 12 11 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN47266.1 - 2.1e-47 158.1 61.3 5.7e-06 26.0 2.7 12.3 12 0 0 12 12 12 11 Regulator of chromosome condensation (RCC1) repeat Tetraspanin PF00335.20 RLN47266.1 - 1.8e-12 47.5 2.8 3.1e-12 46.7 2.8 1.3 1 0 0 1 1 1 1 Tetraspanin family eIF3_p135 PF12807.7 RLN47266.1 - 0.0003 20.9 0.1 0.00056 20.0 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 LMBR1 PF04791.16 RLN47266.1 - 0.038 12.9 0.1 0.069 12.1 0.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein YqjK PF13997.6 RLN47266.1 - 4.4 7.6 5.4 12 6.3 0.1 3.3 3 0 0 3 3 3 0 YqjK-like protein WAPL PF07814.13 RLN47267.1 - 2.6e-08 33.1 5.8 9e-07 28.0 0.6 3.2 2 2 0 2 2 2 2 Wings apart-like protein regulation of heterochromatin Spidroin_MaSp PF11260.8 RLN47267.1 - 0.04 14.2 0.4 0.27 11.6 0.0 2.7 2 0 0 2 2 2 0 Major ampullate spidroin 1 and 2 DUF3348 PF11828.8 RLN47284.1 - 0.00044 20.0 0.2 0.00044 20.0 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3348) ADH_zinc_N_2 PF13602.6 RLN47285.1 - 1.2e-22 81.4 0.0 2.3e-22 80.5 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 RLN47285.1 - 1.3e-17 64.0 0.0 2.4e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN47285.1 - 1.8e-09 37.5 0.6 4.3e-09 36.2 0.6 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain RmlD_sub_bind PF04321.17 RLN47285.1 - 0.018 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Aminotran_5 PF00266.19 RLN47286.1 - 2.2e-72 244.1 0.0 2.8e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 RLN47286.1 - 2.5e-08 33.6 0.1 3.5e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 RLN47286.1 - 5.8e-06 25.9 0.6 2.4e-05 23.9 0.4 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 RLN47286.1 - 0.0023 16.6 0.1 0.0031 16.1 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 RLN47286.1 - 0.0031 16.3 0.1 0.0043 15.8 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain 4_1_CTD PF05902.13 RLN47286.1 - 0.066 13.3 0.5 0.12 12.4 0.5 1.4 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) UcrQ PF02939.16 RLN47293.1 - 2e-07 30.8 0.0 3.1e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 RLN47293.1 - 4.5e-05 23.8 0.0 6.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 Ysc84 PF04366.12 RLN47294.1 - 4.4e-35 120.2 0.1 7.5e-35 119.5 0.1 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator zf-ribbon_3 PF13248.6 RLN47294.1 - 0.055 12.9 2.0 0.14 11.6 2.0 1.7 1 0 0 1 1 1 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 RLN47294.1 - 0.14 12.1 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-C2HC5 PF06221.13 RLN47294.1 - 0.17 11.9 2.3 1.9 8.5 0.4 2.4 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type DUF2542 PF10808.8 RLN47295.1 - 0.0026 18.2 2.4 17 6.0 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2542) ApoO PF09769.9 RLN47295.1 - 0.02 14.8 3.6 32 4.5 0.1 4.2 3 1 1 4 4 4 0 Apolipoprotein O FliE PF02049.18 RLN47295.1 - 0.26 11.4 8.3 21 5.3 0.1 3.9 2 2 1 3 3 3 0 Flagellar hook-basal body complex protein FliE Phage_holin_6_1 PF09682.10 RLN47295.1 - 2.7 8.5 11.8 12 6.4 0.0 4.9 5 1 0 5 5 5 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF5034 PF16437.5 RLN47295.1 - 3.2 7.7 10.3 0.73 9.8 1.0 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF5034) DUF948 PF06103.11 RLN47295.1 - 8.4 6.7 11.0 3.1 8.1 0.7 4.1 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Sod_Fe_N PF00081.22 RLN47295.1 - 8.6 6.9 8.7 5.2 7.6 0.4 3.1 3 0 0 3 3 3 0 Iron/manganese superoxide dismutases, alpha-hairpin domain DHHC PF01529.20 RLN47297.1 - 6.3e-31 107.3 7.7 6.3e-31 107.3 7.7 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.6 RLN47297.1 - 2.4e-22 78.7 2.0 4.5e-09 36.4 0.2 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN47297.1 - 5.9e-22 78.1 3.3 1.1e-08 35.5 0.3 3.9 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 RLN47297.1 - 2.3e-17 62.6 10.1 1.7e-07 31.4 0.1 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 RLN47297.1 - 7.6e-15 55.1 2.1 4.7e-05 23.9 0.0 6.0 3 1 3 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN47297.1 - 1.1e-11 43.9 1.8 0.0024 18.2 0.0 5.8 5 0 0 5 5 5 2 Ankyrin repeat eIF3_subunit PF08597.10 RLN47297.1 - 0.18 11.7 5.2 0.32 10.9 5.2 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit TFIIA PF03153.13 RLN47298.1 - 0.17 11.9 15.7 0.18 11.8 15.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 RLN47298.1 - 0.52 9.6 13.0 0.58 9.4 13.0 1.1 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.13 RLN47298.1 - 1 9.2 15.3 2 8.3 15.3 1.5 1 1 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 RLN47298.1 - 1.6 6.9 18.0 1.9 6.6 18.0 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RLN47298.1 - 2.1 7.7 15.5 2.4 7.5 15.5 1.1 1 0 0 1 1 1 0 SDA1 NPR3 PF03666.13 RLN47298.1 - 2.4 6.9 4.4 2.9 6.6 4.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RXT2_N PF08595.11 RLN47298.1 - 2.8 7.9 10.4 4.3 7.3 10.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 RLN47298.1 - 9.3 5.5 16.3 12 5.1 16.3 1.2 1 0 0 1 1 1 0 NOA36 protein FMN_red PF03358.15 RLN47302.1 - 7.1e-13 48.6 0.0 9.4e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 RLN47302.1 - 2e-08 34.2 0.0 2.6e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 RLN47302.1 - 2.6e-05 24.5 0.2 5.9e-05 23.3 0.1 1.7 2 1 0 2 2 2 1 Flavodoxin Flavodoxin_5 PF12724.7 RLN47302.1 - 0.0028 17.9 0.1 0.19 12.0 0.0 2.2 1 1 1 2 2 2 2 Flavodoxin domain FMN_red PF03358.15 RLN47303.1 - 5.8e-11 42.4 0.0 8.3e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 RLN47303.1 - 1.1e-08 35.0 0.0 1.4e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Cyt-b5 PF00173.28 RLN47304.1 - 6.8e-06 26.1 0.1 0.11 12.7 0.0 2.4 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Ank_2 PF12796.7 RLN47304.1 - 1.5e-05 25.5 0.0 4.7e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN47304.1 - 0.00023 21.6 0.0 0.00048 20.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN47304.1 - 0.0012 19.1 0.1 0.0037 17.6 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN47304.1 - 0.0037 17.6 0.0 0.031 14.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 RLN47304.1 - 0.0061 17.0 0.1 0.048 14.1 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat S-methyl_trans PF02574.16 RLN47305.1 - 6.8e-48 163.8 0.0 7.7e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase S-methyl_trans PF02574.16 RLN47306.1 - 3.5e-44 151.6 0.0 4e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Ank PF00023.30 RLN47307.1 - 6.9e-10 38.9 0.0 1.7e-05 25.0 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 RLN47307.1 - 8.1e-09 36.0 0.1 5.2e-08 33.4 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN47307.1 - 5.4e-08 33.2 0.0 6.2e-07 29.9 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN47307.1 - 6e-06 26.2 0.0 0.00094 19.5 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 RLN47307.1 - 9.8e-06 25.8 0.2 0.0085 16.4 0.0 3.0 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Apc13p PF05839.11 RLN47308.1 - 0.19 11.9 0.1 0.38 11.0 0.1 1.4 1 0 0 1 1 1 0 Apc13p protein PPR_2 PF13041.6 RLN47309.1 - 1.1e-14 54.4 2.3 8.2e-06 25.9 0.0 8.1 9 0 0 9 9 9 2 PPR repeat family PPR_3 PF13812.6 RLN47309.1 - 2.4e-13 49.9 0.0 5.8e-06 26.3 0.0 4.9 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR_long PF17177.4 RLN47309.1 - 2.4e-10 40.1 5.9 0.27 10.6 0.1 6.6 2 1 3 5 5 5 4 Pentacotripeptide-repeat region of PRORP ANAPC4_WD40 PF12894.7 RLN47309.1 - 1e-09 38.5 2.9 0.00019 21.7 0.1 5.1 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PPR PF01535.20 RLN47309.1 - 1.4e-09 37.5 10.9 0.0048 17.1 0.1 8.7 9 0 0 9 9 8 1 PPR repeat Coatomer_WDAD PF04053.14 RLN47309.1 - 8.3e-07 28.4 1.1 0.026 13.6 0.0 3.0 2 1 1 3 3 3 2 Coatomer WD associated region zf-UDP PF14569.6 RLN47309.1 - 0.00092 19.3 1.2 0.00092 19.3 1.2 2.7 3 0 0 3 3 2 1 Zinc-binding RING-finger Clathrin PF00637.20 RLN47309.1 - 0.0075 16.1 7.0 0.035 14.0 0.1 5.1 4 1 2 6 6 6 1 Region in Clathrin and VPS TPR_7 PF13176.6 RLN47309.1 - 0.063 13.3 12.3 3.7 7.8 0.0 7.7 6 2 1 7 7 7 0 Tetratricopeptide repeat WD40 PF00400.32 RLN47309.1 - 0.16 12.9 1.7 11 7.1 0.0 4.1 4 0 0 4 4 3 0 WD domain, G-beta repeat Vps39_1 PF10366.9 RLN47309.1 - 0.21 11.9 3.1 9.8 6.5 0.5 3.6 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 ANAPC3 PF12895.7 RLN47309.1 - 0.59 10.4 17.9 2.5 8.4 0.5 5.6 5 0 0 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 RLN47309.1 - 0.6 10.0 7.8 3.3 7.7 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN47309.1 - 0.96 10.4 22.3 23 6.2 0.1 8.8 9 1 1 10 10 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN47309.1 - 1.2 9.4 12.3 5.4 7.4 0.0 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat zf-RING_4 PF14570.6 RLN47309.1 - 2.9 7.8 14.1 1.1 9.1 8.7 2.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain TPR_19 PF14559.6 RLN47309.1 - 6.1 7.4 21.8 0.069 13.7 0.2 6.5 9 0 0 9 9 7 0 Tetratricopeptide repeat FMN_red PF03358.15 RLN47310.1 - 1.5e-13 50.8 0.0 2.2e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 RLN47310.1 - 1.4e-07 31.4 0.0 1.9e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 RLN47310.1 - 0.0012 19.1 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin PI3_PI4_kinase PF00454.27 RLN47311.1 - 2e-32 113.0 0.0 3.5e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pico_P2A PF00947.19 RLN47311.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Picornavirus core protein 2A YjgF_endoribonc PF14588.6 RLN47312.1 - 5.3e-27 94.8 0.0 6.4e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 RLN47312.1 - 4.6e-18 65.4 0.0 7.6e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP SET PF00856.28 RLN47313.1 - 0.00013 22.4 0.3 0.012 16.0 0.3 2.4 1 1 0 1 1 1 1 SET domain NT5C PF06941.12 RLN47314.1 - 4.5e-10 39.7 0.1 7.3e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Alba PF01918.21 RLN47314.1 - 3e-05 23.8 0.4 8.7e-05 22.3 0.4 1.7 1 0 0 1 1 1 1 Alba DHQ_synthase PF01761.20 RLN47314.1 - 0.01 15.0 0.6 0.021 14.0 0.1 1.7 2 0 0 2 2 2 0 3-dehydroquinate synthase Usp PF00582.26 RLN47314.1 - 1.8 9.0 6.2 24 5.4 4.3 2.6 2 1 0 2 2 2 0 Universal stress protein family LAMTOR PF15454.6 RLN47315.1 - 0.015 15.9 0.0 0.044 14.4 0.0 1.8 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF1062 PF06353.12 RLN47317.1 - 0.89 10.4 11.3 0.56 11.0 7.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1062) DUF3747 PF12565.8 RLN47318.1 - 0.0011 18.3 0.1 0.0039 16.6 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3747) PKcGMP_CC PF16808.5 RLN47319.1 - 0.056 13.3 9.0 0.07 13.0 0.7 3.9 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase His_Phos_1 PF00300.22 RLN47320.1 - 1.9e-20 73.4 0.1 8.6e-14 51.7 0.1 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) NOGCT PF08155.11 RLN47320.1 - 0.1 12.6 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 NOGCT (NUC087) domain RIC1 PF07064.13 RLN47321.1 - 0.0041 16.6 0.7 0.39 10.1 0.4 2.1 1 1 1 2 2 2 2 RIC1 Mad3_BUB1_I_2 PF17014.5 RLN47321.1 - 0.07 13.2 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein TPR_10 PF13374.6 RLN47321.1 - 0.088 12.7 0.7 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR_2 PF13041.6 RLN47322.1 - 2.3e-06 27.7 0.1 0.079 13.2 0.0 2.8 2 1 0 2 2 2 2 PPR repeat family Mad3_BUB1_II PF08171.11 RLN47322.1 - 0.00087 19.4 0.1 0.0016 18.5 0.1 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 MRP-S27 PF10037.9 RLN47322.1 - 0.0012 17.8 0.6 0.003 16.5 0.1 1.7 1 1 1 2 2 2 1 Mitochondrial 28S ribosomal protein S27 PPR_3 PF13812.6 RLN47322.1 - 0.025 14.6 0.2 0.1 12.7 0.1 2.0 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Carn_acyltransf PF00755.20 RLN47323.1 - 6.1e-165 550.2 0.1 3.2e-99 333.2 0.1 2.0 1 1 1 2 2 2 2 Choline/Carnitine o-acyltransferase Astacin PF01400.24 RLN47324.1 - 4.6e-20 72.0 0.0 1.1e-19 70.9 0.0 1.6 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) FMN_red PF03358.15 RLN47325.1 - 7e-14 51.8 0.0 9.1e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 RLN47325.1 - 6.5e-08 32.5 0.0 8.3e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 RLN47325.1 - 4.1e-05 23.8 0.0 8.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 RLN47325.1 - 0.02 15.1 0.0 0.36 11.0 0.0 2.1 1 1 1 2 2 2 0 Flavodoxin domain adh_short_C2 PF13561.6 RLN47339.1 - 2.6e-64 217.0 5.5 3.1e-64 216.8 5.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RLN47339.1 - 7e-47 159.4 3.3 8.8e-47 159.1 3.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RLN47339.1 - 3.4e-11 43.4 5.1 5.8e-11 42.6 4.9 1.6 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 RLN47339.1 - 0.00074 19.5 3.7 0.0019 18.1 2.8 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 RLN47339.1 - 0.0087 16.2 1.8 0.017 15.3 1.8 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 RLN47339.1 - 0.014 14.5 0.1 0.022 13.9 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 RLN47339.1 - 0.07 12.6 0.3 0.11 12.0 0.3 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family YmgD PF16456.5 RLN47339.1 - 0.18 11.9 5.8 0.095 12.8 2.7 2.0 2 0 0 2 2 2 0 YmgD protein Questin_oxidase PF14027.6 RLN47340.1 - 1.8e-12 47.5 1.1 2.1e-12 47.3 1.1 1.0 1 0 0 1 1 1 1 Questin oxidase-like GATase PF00117.28 RLN47341.1 - 4.8e-16 59.1 0.0 7.1e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 RLN47341.1 - 1.5e-05 24.8 0.0 3.4e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Peptidase C26 Aldedh PF00171.22 RLN47342.1 - 7.8e-88 295.0 0.2 1.5e-60 205.0 0.0 3.0 1 1 2 3 3 3 3 Aldehyde dehydrogenase family ERO1 PF04137.15 RLN47343.1 - 6.5e-121 403.8 0.2 8.4e-121 403.5 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) HSP90 PF00183.18 RLN47343.1 - 0.09 11.7 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Hsp90 protein Sas6_CC PF18594.1 RLN47343.1 - 1.6 8.6 3.6 2 8.3 2.1 1.9 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain NRN1 PF15056.6 RLN47343.1 - 4.5 7.4 6.9 1.7 8.8 0.4 2.8 3 0 0 3 3 3 0 Neuritin protein family GATase PF00117.28 RLN47344.1 - 3.2e-11 43.4 0.0 5e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I tRNA-synt_2b PF00587.25 RLN47345.1 - 1.1e-07 32.0 0.1 1.3e-07 31.7 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DAGK_cat PF00781.24 RLN47352.1 - 1.8e-25 88.9 0.0 5e-25 87.6 0.0 1.8 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DHHC PF01529.20 RLN47353.1 - 6.2e-08 32.8 5.3 6.2e-08 32.8 5.3 3.0 2 2 0 2 2 2 1 DHHC palmitoyltransferase DUF4732 PF15876.5 RLN47353.1 - 0.058 13.5 0.0 0.09 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4732) BT1 PF03092.16 RLN47354.1 - 2.4e-11 42.6 8.5 8.2e-09 34.2 2.1 2.4 2 0 0 2 2 2 2 BT1 family MFS_1_like PF12832.7 RLN47354.1 - 0.18 10.6 15.4 0.0063 15.4 8.1 2.1 3 0 0 3 3 3 0 MFS_1 like family Mob1_phocein PF03637.17 RLN47358.1 - 0.035 14.1 0.0 0.041 13.9 0.0 1.1 1 0 0 1 1 1 0 Mob1/phocein family Phos_pyr_kin PF08543.12 RLN47359.1 - 2.3e-13 50.1 0.0 1.4e-12 47.6 0.0 2.0 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 RLN47359.1 - 2.1e-09 37.1 0.0 2.2e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 pfkB family carbohydrate kinase PCI PF01399.27 RLN47360.1 - 2.7e-16 60.0 0.6 8.8e-16 58.3 0.6 1.9 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.6 RLN47360.1 - 0.00024 20.9 0.3 1.5 9.0 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 RLN47360.1 - 0.0014 18.6 0.1 0.0036 17.3 0.1 1.7 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family TPR_2 PF07719.17 RLN47360.1 - 0.031 14.4 0.1 0.21 11.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN47360.1 - 0.049 13.5 0.3 0.26 11.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN47360.1 - 0.12 12.3 0.6 3.4 7.7 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat YL1 PF05764.13 RLN47360.1 - 1.4 9.0 5.9 2.1 8.4 5.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Got1 PF04178.12 RLN47361.1 - 7.2e-31 106.9 14.1 9.8e-31 106.5 14.1 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family LEA_5 PF00477.17 RLN47361.1 - 0.045 14.2 0.1 0.067 13.7 0.1 1.2 1 0 0 1 1 1 0 Small hydrophilic plant seed protein PH PF00169.29 RLN47362.1 - 0.00011 22.6 0.0 0.00023 21.6 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN47362.1 - 0.018 15.3 0.1 0.04 14.2 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Pkinase PF00069.25 RLN47363.1 - 4.9e-47 160.5 0.0 7.2e-24 84.6 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN47363.1 - 2.5e-18 66.3 0.0 3.7e-13 49.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase UPF0492 PF15744.5 RLN47363.1 - 0.018 14.3 4.1 0.029 13.6 4.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 NblA PF04485.12 RLN47363.1 - 0.084 13.3 0.3 0.16 12.4 0.3 1.4 1 0 0 1 1 1 0 Phycobilisome degradation protein nblA Pox_ser-thr_kin PF05445.11 RLN47363.1 - 0.17 10.8 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HTH_OrfB_IS605 PF12323.8 RLN47365.1 - 1.2e-08 34.3 1.5 3.2e-08 32.9 1.5 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain OrfB_Zn_ribbon PF07282.11 RLN47365.1 - 0.085 12.8 0.4 0.24 11.4 0.4 1.8 1 0 0 1 1 1 0 Putative transposase DNA-binding domain AsnA PF03590.15 RLN47365.1 - 0.13 11.9 0.1 0.35 10.6 0.0 1.7 2 0 0 2 2 2 0 Aspartate-ammonia ligase Pro_isomerase PF00160.21 RLN47374.1 - 3.2e-17 63.3 0.1 4.6e-17 62.7 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ank_2 PF12796.7 RLN47375.1 - 0.037 14.6 0.0 0.089 13.4 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN47375.1 - 0.098 13.3 0.0 0.26 11.9 0.0 1.7 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.30 RLN47375.1 - 0.13 12.8 0.1 0.42 11.1 0.1 1.9 1 0 0 1 1 1 0 Ankyrin repeat Pkinase_Tyr PF07714.17 RLN47375.1 - 0.17 11.1 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase DUF667 PF05018.13 RLN47376.1 - 3.7e-55 186.5 0.0 6.1e-55 185.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Ank_4 PF13637.6 RLN47376.1 - 1.1e-46 156.6 33.2 2.8e-06 27.7 0.3 11.8 6 3 9 15 15 15 14 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN47376.1 - 4.5e-41 139.3 15.6 3.4e-08 34.0 0.2 7.7 1 1 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN47376.1 - 3.3e-38 129.2 38.0 0.00026 21.2 0.2 16.6 4 2 13 17 17 17 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN47376.1 - 2.1e-17 61.4 23.8 2.6 8.9 0.0 15.2 8 6 8 16 16 16 4 Ankyrin repeat Ank PF00023.30 RLN47376.1 - 1.2e-09 38.1 8.6 2.6 8.6 0.0 10.4 6 3 3 10 10 10 2 Ankyrin repeat mRNA_triPase PF02940.15 RLN47377.1 - 1.8e-18 67.1 0.0 1.2e-17 64.4 0.0 2.0 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain mRNA_cap_enzyme PF01331.19 RLN47377.1 - 4.6e-14 52.7 0.0 7.2e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.21 RLN47377.1 - 0.00043 20.0 0.0 0.0058 16.3 0.0 2.2 1 1 0 1 1 1 1 ATP dependent DNA ligase domain UDPGP PF01704.18 RLN47378.1 - 1.7e-122 409.1 0.0 2.2e-122 408.7 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PGM_PMM_I PF02878.16 RLN47378.1 - 5.2e-29 100.7 0.0 1.7e-28 99.0 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 RLN47378.1 - 1.1e-25 90.1 0.0 2.4e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 RLN47378.1 - 5.6e-07 30.1 0.1 3.1e-06 27.8 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 RLN47378.1 - 0.00023 21.2 0.0 0.00081 19.5 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain His_Phos_1 PF00300.22 RLN47401.1 - 1.7e-10 40.9 0.1 5.4e-10 39.3 0.1 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Acyl_transf_1 PF00698.21 RLN47401.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 Acyl transferase domain His_Phos_1 PF00300.22 RLN47402.1 - 1.7e-16 60.5 0.0 5.5e-16 58.8 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HTH_Tnp_Tc5 PF03221.16 RLN47403.1 - 5.3e-05 23.2 0.0 8.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain OrfB_Zn_ribbon PF07282.11 RLN47404.1 - 4.8e-14 52.0 0.8 9.4e-14 51.1 0.8 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 RLN47404.1 - 1.2e-06 28.7 5.5 1.9e-06 28.1 1.7 2.5 2 1 0 2 2 2 1 Probable transposase C1_2 PF03107.16 RLN47404.1 - 0.057 13.8 1.1 0.14 12.5 1.1 1.6 1 0 0 1 1 1 0 C1 domain RF-1 PF00472.20 RLN47404.1 - 0.072 13.0 0.3 0.17 11.8 0.3 1.7 1 0 0 1 1 1 0 RF-1 domain DUF1272 PF06906.11 RLN47404.1 - 0.16 12.1 2.8 5.5 7.2 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Endonuclease_5 PF04493.14 RLN47406.1 - 2.1e-39 135.3 0.1 4.8e-39 134.1 0.0 1.5 2 0 0 2 2 2 1 Endonuclease V DUF3619 PF12279.8 RLN47406.1 - 0.015 15.7 0.6 0.048 14.0 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3619) DHHC PF01529.20 RLN47407.1 - 2.1e-28 99.1 11.1 2.1e-28 99.1 11.1 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase Spt4 PF06093.13 RLN47407.1 - 0.087 12.9 4.9 0.15 12.2 4.9 1.3 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Phage_holin_3_6 PF07332.11 RLN47407.1 - 1.1 9.3 7.2 1.5 8.9 0.3 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Kin17_mid PF10357.9 RLN47408.1 - 5.8e-48 162.0 1.1 5.8e-48 162.0 1.1 2.2 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 RLN47408.1 - 6e-25 87.1 3.1 7.1e-25 86.9 2.0 1.7 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain zf-met PF12874.7 RLN47408.1 - 0.0036 17.6 5.0 0.0086 16.4 5.0 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RLN47408.1 - 0.33 11.3 2.7 0.31 11.4 0.5 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) KOW PF00467.29 RLN47408.1 - 0.41 10.7 2.3 2.2 8.3 0.1 2.8 2 0 0 2 2 2 0 KOW motif zf-C2H2_jaz PF12171.8 RLN47408.1 - 1.9 8.9 11.4 0.052 13.8 4.8 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding THOC7 PF05615.13 RLN47409.1 - 2.1e-13 50.7 1.9 2.1e-13 50.7 1.9 2.1 1 1 0 2 2 2 1 Tho complex subunit 7 DUF4407 PF14362.6 RLN47409.1 - 0.069 12.5 7.4 0.085 12.2 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HCMV_UL139 PF12507.8 RLN47409.1 - 0.28 11.6 3.8 0.28 11.5 2.1 1.8 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein HAUS6_N PF14661.6 RLN47409.1 - 5.1 6.6 11.4 33 4.0 9.9 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF465 PF04325.13 RLN47409.1 - 5.8 7.0 9.2 7.8 6.6 0.6 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF465) WD40 PF00400.32 RLN47410.1 - 1.2e-28 98.7 23.3 2.6e-06 28.1 1.8 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN47410.1 - 0.001 19.3 0.9 1.7 9.0 0.0 4.5 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DNA_pol_A_exo1 PF01612.20 RLN47412.1 - 2.8e-19 69.5 0.0 5.4e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease Pkinase PF00069.25 RLN47413.1 - 1.8e-15 57.0 0.4 2.4e-14 53.4 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN47413.1 - 3.9e-08 32.9 0.3 1e-07 31.5 0.2 1.4 1 1 1 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 RLN47413.1 - 0.0033 16.8 0.4 0.012 15.0 0.2 1.8 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN47413.1 - 0.013 15.4 0.8 0.37 10.7 0.1 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 RLN47413.1 - 0.016 14.8 0.0 1.6 8.2 0.0 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase Kinase-like PF14531.6 RLN47413.1 - 0.033 13.5 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 RLN47413.1 - 0.15 10.8 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase IlvN PF07991.12 RLN47414.1 - 7.7e-06 25.6 0.1 1.3e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Myosin_head PF00063.21 RLN47420.1 - 1.2e-112 377.4 0.0 1.9e-112 376.7 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Tho1_MOS11_C PF18592.1 RLN47420.1 - 0.00062 19.5 12.9 0.086 12.7 2.0 2.8 1 1 2 3 3 3 3 Tho1/MOS11 C-terminal domain AAA_16 PF13191.6 RLN47420.1 - 0.011 16.1 1.1 0.023 15.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 RLN47420.1 - 0.15 12.3 0.1 0.38 11.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain C1_1 PF00130.22 RLN47424.1 - 0.053 13.4 3.6 0.11 12.4 3.6 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2804 PF10974.8 RLN47427.1 - 1e-39 137.0 0.0 1.4e-39 136.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) FYVE PF01363.21 RLN47428.1 - 2e-06 27.8 19.7 5.7e-06 26.4 17.5 2.2 2 0 0 2 2 2 1 FYVE zinc finger zf-C2H2_4 PF13894.6 RLN47428.1 - 1.3 10.0 7.0 5.2 8.2 0.3 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger FYVE PF01363.21 RLN47429.1 - 1.2e-06 28.5 7.1 3.6e-06 27.0 7.1 1.8 1 0 0 1 1 1 1 FYVE zinc finger WW PF00397.26 RLN47429.1 - 0.0082 16.2 0.8 0.02 15.0 0.8 1.7 1 0 0 1 1 1 1 WW domain Condensin2nSMC PF12422.8 RLN47429.1 - 0.014 15.5 0.1 2.8 8.1 0.0 2.5 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit zf-RING_UBOX PF13445.6 RLN47429.1 - 0.039 14.0 6.0 0.032 14.2 3.1 2.4 2 0 0 2 2 2 0 RING-type zinc-finger DUF3802 PF12290.8 RLN47429.1 - 0.15 12.6 0.1 19 5.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) zf-RING_2 PF13639.6 RLN47429.1 - 2.3 8.6 7.8 8.7 6.8 7.8 2.1 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 RLN47429.1 - 5.3 7.0 7.8 3.2 7.7 4.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_3 PF07859.13 RLN47447.1 - 4.4e-31 108.4 0.1 5e-31 108.2 0.1 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN47447.1 - 1.4e-08 34.0 0.0 1.8e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 RLN47447.1 - 3.2e-05 23.5 0.1 0.00024 20.6 0.1 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 RLN47447.1 - 0.049 13.5 0.0 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PRP38 PF03371.15 RLN47448.1 - 1.6e-51 174.7 0.0 2.4e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 RLN47448.1 - 0.021 15.4 39.3 0.021 15.4 39.3 2.9 2 1 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Ribosomal_L19e PF01280.20 RLN47448.1 - 0.69 10.0 15.1 1.7 8.7 15.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L19e CDC45 PF02724.14 RLN47448.1 - 1.3 7.2 11.8 2.4 6.4 11.8 1.3 1 0 0 1 1 1 0 CDC45-like protein PH PF00169.29 RLN47449.1 - 2.3e-18 66.7 3.9 1.3e-09 38.5 0.2 3.3 2 2 0 2 2 2 2 PH domain PH_11 PF15413.6 RLN47449.1 - 4.9e-06 26.9 8.1 0.0028 18.0 1.4 4.0 2 2 0 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.6 RLN47449.1 - 0.0036 17.6 5.3 0.17 12.2 0.7 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain DUF4407 PF14362.6 RLN47453.1 - 0.025 14.0 0.2 0.025 13.9 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3138 PF11336.8 RLN47453.1 - 0.035 12.7 0.1 0.035 12.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Spc7 PF08317.11 RLN47453.1 - 0.062 12.2 0.0 0.066 12.1 0.0 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Sde2_N_Ubi PF13019.6 RLN47453.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain ABC_membrane PF00664.23 RLN47454.1 - 1.1e-78 264.6 30.3 8.2e-40 137.2 10.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN47454.1 - 1.4e-55 187.5 0.2 1.9e-31 109.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN47454.1 - 3e-11 43.2 9.6 0.0035 16.8 0.1 4.4 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RLN47454.1 - 2.3e-06 27.2 0.5 0.091 12.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 RLN47454.1 - 2.8e-06 27.4 0.3 0.016 15.3 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RLN47454.1 - 3.7e-05 23.7 0.0 0.39 10.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 RLN47454.1 - 8.9e-05 22.4 1.4 0.76 9.5 0.0 4.0 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RLN47454.1 - 0.0015 19.1 0.3 1.6 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 RLN47454.1 - 0.012 15.3 0.0 2 8.1 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Roc PF08477.13 RLN47454.1 - 0.016 15.4 0.2 0.92 9.7 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 RLN47454.1 - 0.019 15.4 1.4 1.7 9.0 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 RLN47454.1 - 0.022 15.0 2.2 7.5 6.8 0.2 2.9 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 RLN47454.1 - 0.026 14.1 1.2 1 8.9 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 RLN47454.1 - 0.032 14.2 1.2 0.62 10.0 0.0 2.9 3 0 0 3 3 3 0 NACHT domain Zeta_toxin PF06414.12 RLN47454.1 - 0.037 13.3 1.0 7.6 5.8 0.1 2.8 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 RLN47454.1 - 0.11 11.7 2.0 6 6.0 0.0 3.0 2 1 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 RLN47454.1 - 0.15 11.7 3.0 5.2 6.7 0.1 2.9 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 RLN47454.1 - 0.21 11.7 6.8 0.99 9.5 0.1 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain Dynamin_N PF00350.23 RLN47454.1 - 0.26 11.3 10.3 0.82 9.7 0.2 3.2 4 0 0 4 4 3 0 Dynamin family ATP1G1_PLM_MAT8 PF02038.16 RLN47454.1 - 0.84 9.1 9.3 9.4 5.8 0.2 3.6 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family p450 PF00067.22 RLN47455.1 - 6.4e-72 242.8 0.0 8.1e-72 242.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 RLN47456.1 - 2.4e-70 237.6 0.0 2.9e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 OB_NTP_bind PF07717.16 RLN47457.1 - 1.3e-21 76.7 0.1 4.4e-21 75.0 0.1 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 RLN47457.1 - 6.7e-21 74.6 0.0 6.7e-21 74.6 0.0 3.2 3 1 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 RLN47457.1 - 1.6e-12 47.8 0.0 4e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RLN47457.1 - 5.9e-07 29.4 0.0 1.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RLN47457.1 - 0.00023 21.5 0.0 0.00073 19.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RLN47457.1 - 0.00028 20.7 0.0 0.00092 19.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 RLN47457.1 - 0.00074 18.7 0.0 0.0021 17.2 0.0 1.8 1 1 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 RLN47457.1 - 0.00093 18.5 0.0 0.0026 17.1 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 RLN47457.1 - 0.0012 19.2 0.0 0.0031 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 RLN47457.1 - 0.019 14.9 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain CRF PF00473.17 RLN47457.1 - 0.1 12.7 0.2 0.32 11.1 0.2 1.8 1 0 0 1 1 1 0 Corticotropin-releasing factor family p450 PF00067.22 RLN47458.1 - 8.1e-05 21.5 0.0 9.7e-05 21.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HTH_OrfB_IS605 PF12323.8 RLN47459.1 - 1.4e-08 34.1 0.0 4.4e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain OrfB_Zn_ribbon PF07282.11 RLN47459.1 - 6.9e-06 25.9 0.9 1.2e-05 25.1 0.2 1.8 2 0 0 2 2 2 1 Putative transposase DNA-binding domain YwqJ-deaminase PF14431.6 RLN47459.1 - 0.03 14.5 0.8 0.099 12.8 0.2 2.0 2 0 0 2 2 2 0 YwqJ-like deaminase DUF1364 PF07102.12 RLN47459.1 - 0.084 12.7 0.7 0.39 10.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1364) zf-Tim10_DDP PF02953.15 RLN47460.1 - 8.1e-05 22.2 0.2 9.7e-05 21.9 0.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Sel1 PF08238.12 RLN47461.1 - 4.3e-21 74.9 17.0 0.00011 22.7 1.4 8.4 8 0 0 8 8 8 5 Sel1 repeat Laminin_B PF00052.18 RLN47461.1 - 7.8e-11 42.0 0.0 2.8e-10 40.2 0.0 1.9 1 1 0 1 1 1 1 Laminin B (Domain IV) SLAIN PF15301.6 RLN47461.1 - 0.045 13.0 0.6 0.069 12.4 0.6 1.1 1 0 0 1 1 1 0 SLAIN motif-containing family TPR_11 PF13414.6 RLN47461.1 - 0.085 12.6 1.6 3.3 7.5 0.3 3.5 3 0 0 3 3 3 0 TPR repeat NAM-associated PF14303.6 RLN47461.1 - 0.18 12.5 6.7 0.3 11.8 6.7 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain PerC PF06069.11 RLN47461.1 - 0.34 11.2 1.9 0.98 9.7 1.9 1.7 1 0 0 1 1 1 0 PerC transcriptional activator TPR_1 PF00515.28 RLN47461.1 - 1.4 8.8 11.0 65 3.6 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Exo_endo_phos PF03372.23 RLN47462.1 - 1.6e-13 50.7 0.0 3.8e-13 49.5 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HEAT PF02985.22 RLN47464.1 - 2.4e-08 33.5 9.5 4.2 7.9 0.0 7.4 6 1 1 7 7 7 4 HEAT repeat HEAT_2 PF13646.6 RLN47464.1 - 7e-06 26.3 10.9 0.47 10.9 0.0 5.5 4 2 1 5 5 5 2 HEAT repeats Cnd1 PF12717.7 RLN47464.1 - 0.0014 18.6 0.4 2 8.4 0.0 3.7 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 RLN47464.1 - 0.1 12.8 0.9 3.5 7.8 0.0 3.4 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 GLTSCR1 PF15249.6 RLN47464.1 - 0.16 12.4 0.5 1.5 9.3 0.0 2.4 2 0 0 2 2 2 0 Conserved region of unknown function on GLTSCR protein HEAT_EZ PF13513.6 RLN47464.1 - 0.32 11.5 18.1 15 6.2 0.4 6.8 7 1 1 8 8 8 0 HEAT-like repeat DUF3034 PF11231.8 RLN47465.1 - 0.066 12.8 0.0 0.085 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3034) Myosin_head PF00063.21 RLN47466.1 - 2.7e-224 746.3 0.3 4e-224 745.8 0.3 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Ank_2 PF12796.7 RLN47466.1 - 1.5e-32 112.0 4.8 1e-11 45.2 0.5 4.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 RLN47466.1 - 5.3e-29 99.4 9.0 0.0048 17.3 0.1 8.5 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 RLN47466.1 - 2e-26 92.0 5.6 2.5e-07 31.1 0.1 7.1 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN47466.1 - 2.9e-25 88.0 10.1 2.1e-09 37.4 0.1 6.7 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN47466.1 - 1.2e-23 80.6 2.4 0.015 15.8 0.0 8.4 8 0 0 8 8 8 5 Ankyrin repeat FYVE PF01363.21 RLN47466.1 - 3e-16 59.3 14.9 7.3e-16 58.1 14.9 1.7 1 0 0 1 1 1 1 FYVE zinc finger IQ PF00612.27 RLN47466.1 - 1.8e-06 27.2 2.5 0.056 13.3 0.6 3.1 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_16 PF13191.6 RLN47466.1 - 0.036 14.4 0.0 0.17 12.2 0.0 2.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 RLN47466.1 - 0.098 12.9 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain EGF_2 PF07974.13 RLN47467.1 - 5.7e-09 36.2 52.8 0.0012 19.1 3.4 6.8 5 1 1 6 6 6 5 EGF-like domain DUF2644 PF10841.8 RLN47467.1 - 0.083 13.1 0.1 0.24 11.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2644) EGF PF00008.27 RLN47467.1 - 0.16 12.3 45.7 0.18 12.2 1.5 6.8 6 0 0 6 6 6 0 EGF-like domain LRR_4 PF12799.7 RLN47468.1 - 3.3e-08 33.7 10.9 4e-05 23.9 2.3 3.4 1 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN47468.1 - 2.5e-07 30.3 11.8 2.1e-05 24.2 2.9 2.8 2 1 1 3 3 3 2 Leucine rich repeat FAM194 PF14977.6 RLN47468.1 - 0.061 12.6 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 FAM194 protein LRR_9 PF14580.6 RLN47468.1 - 0.08 12.4 0.7 0.38 10.2 0.3 2.1 1 1 0 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.33 RLN47468.1 - 1.8 9.4 7.5 1.3e+02 3.7 1.0 4.6 3 1 0 3 3 3 0 Leucine Rich Repeat DUF3357 PF11837.8 RLN47469.1 - 0.089 13.3 0.2 0.17 12.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) TPR_1 PF00515.28 RLN47470.1 - 4.6e-20 70.5 0.0 2.6e-06 27.0 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN47470.1 - 8.3e-17 59.9 0.0 2.8e-05 23.9 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN47470.1 - 4.8e-11 42.2 0.1 0.0027 17.4 0.0 3.3 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 RLN47470.1 - 4.9e-11 41.9 0.0 0.0027 17.8 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 RLN47470.1 - 2.8e-07 30.7 0.5 0.00034 20.8 0.4 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN47470.1 - 3e-07 30.7 2.2 0.029 15.2 0.4 3.7 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 RLN47470.1 - 6.7e-07 29.8 0.7 0.015 15.9 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN47470.1 - 6.8e-06 26.1 1.9 0.085 13.3 0.0 4.1 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN47470.1 - 4.2e-05 23.3 1.8 3.8 7.8 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN47470.1 - 0.00017 22.0 0.4 0.015 15.8 0.3 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN47470.1 - 0.00022 21.3 0.9 0.05 13.8 0.4 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN47470.1 - 0.00072 20.0 0.0 0.11 13.1 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.7 RLN47470.1 - 0.002 18.2 0.1 1.6 8.8 0.0 2.5 1 1 1 2 2 2 2 Domain of Unknown Function (DUF3856) TPR_15 PF13429.6 RLN47470.1 - 0.0022 17.3 0.1 0.17 11.0 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 RLN47470.1 - 0.01 16.3 0.4 0.01 16.3 0.4 1.7 2 0 0 2 2 2 0 Bacterial transcriptional activator domain baeRF_family3 PF18845.1 RLN47470.1 - 0.033 14.4 1.0 0.088 13.1 0.0 1.9 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 ANAPC3 PF12895.7 RLN47470.1 - 0.042 14.1 1.0 0.26 11.5 1.1 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 OSCP PF00213.18 RLN47470.1 - 0.05 13.7 1.2 0.085 13.0 0.0 1.9 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit PCRF PF03462.18 RLN47470.1 - 0.86 9.4 5.5 3.6 7.4 0.2 2.1 2 0 0 2 2 2 0 PCRF domain WD40 PF00400.32 RLN47471.1 - 2.9e-43 145.0 6.7 1.1e-07 32.4 0.3 8.0 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN47471.1 - 3.8e-18 65.6 0.0 0.00072 19.8 0.0 5.9 4 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN47471.1 - 3.1e-11 42.6 4.4 0.0055 15.4 0.0 4.1 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RLN47471.1 - 4.2e-07 29.2 0.3 0.63 8.9 0.0 4.8 3 1 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 RLN47471.1 - 3.2e-06 27.2 0.0 0.0006 19.8 0.0 3.5 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 RLN47471.1 - 0.0023 16.4 0.0 0.015 13.7 0.0 2.1 3 0 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 RLN47471.1 - 0.0041 16.5 0.0 0.011 15.0 0.0 1.7 2 0 0 2 2 2 1 WD40-like domain Cytochrom_D1 PF02239.16 RLN47471.1 - 0.0046 15.5 0.0 0.048 12.2 0.0 2.3 2 1 1 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 RLN47471.1 - 0.011 14.6 0.0 0.63 8.7 0.0 2.9 3 0 0 3 3 3 0 Nup133 N terminal like Cystatin PF00031.21 RLN47472.1 - 0.02 15.2 0.2 0.066 13.5 0.1 1.8 1 1 1 2 2 2 0 Cystatin domain Trp_oprn_chp PF09534.10 RLN47472.1 - 0.12 12.2 12.0 0.15 11.9 0.2 2.7 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SQAPI PF16845.5 RLN47472.1 - 0.19 12.1 1.0 0.38 11.1 0.1 2.0 2 0 0 2 2 2 0 Aspartic acid proteinase inhibitor IQ PF00612.27 RLN47473.1 - 8e-05 22.1 0.1 0.00017 21.1 0.1 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif BLOC1_2 PF10046.9 RLN47473.1 - 0.057 13.7 17.6 0.43 10.9 9.1 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 RLN47473.1 - 0.21 11.6 8.4 17 5.4 6.2 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TEX12 PF15219.6 RLN47473.1 - 0.63 10.4 4.3 0.36 11.2 0.5 2.5 2 1 0 2 2 2 0 Testis-expressed 12 FlaC_arch PF05377.11 RLN47473.1 - 0.89 10.0 11.2 4.7 7.7 0.4 4.1 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) ApoO PF09769.9 RLN47473.1 - 4.5 7.2 8.1 5.2 7.1 0.8 3.2 2 1 0 3 3 3 0 Apolipoprotein O Viral_P18 PF04521.13 RLN47473.1 - 8.9 6.1 10.1 2.2 8.1 3.5 2.4 2 1 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein zf-C2H2 PF00096.26 RLN47474.1 - 6.9e-10 38.8 48.4 0.0052 17.2 3.8 6.4 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RLN47474.1 - 2.1e-09 37.4 45.0 8.3e-06 26.0 2.7 6.1 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 RLN47474.1 - 2.6e-06 27.8 45.9 0.16 12.9 3.3 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger SlyX PF04102.12 RLN47474.1 - 0.0024 18.5 0.0 0.0054 17.3 0.0 1.6 1 0 0 1 1 1 1 SlyX FOXP-CC PF16159.5 RLN47474.1 - 0.089 13.4 9.5 2.1 9.0 1.2 3.9 3 1 0 3 3 3 0 FOXP coiled-coil domain Mis14 PF08641.12 RLN47474.1 - 0.19 12.0 0.4 0.36 11.1 0.2 1.5 2 0 0 2 2 1 0 Kinetochore protein Mis14 like zf-C2H2_aberr PF17017.5 RLN47474.1 - 0.6 10.2 9.6 4.8 7.3 0.1 3.4 2 1 1 3 3 3 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 RLN47474.1 - 0.62 10.1 27.8 0.07 13.2 1.2 4.6 5 0 0 5 5 5 0 C2H2-type zinc finger zf-met PF12874.7 RLN47474.1 - 1.7 9.1 23.6 2.1 8.9 0.3 5.7 6 0 0 6 6 6 0 Zinc-finger of C2H2 type IBR PF01485.21 RLN47474.1 - 3.8 7.8 13.6 2.6 8.3 1.2 3.2 3 1 1 4 4 4 0 IBR domain, a half RING-finger domain zf-C2H2_9 PF16293.5 RLN47474.1 - 9.7 6.1 6.3 6.5 6.7 0.1 3.4 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) CytochromB561_N PF09786.9 RLN47475.1 - 1.6e-15 57.1 0.1 2.2e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome B561, N terminal Casc1 PF12366.8 RLN47475.1 - 0.056 13.0 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 WD40 PF00400.32 RLN47476.1 - 2.9e-43 145.0 14.9 2.7e-08 34.4 0.1 12.4 13 0 0 13 13 13 7 WD domain, G-beta repeat Utp12 PF04003.12 RLN47476.1 - 3.6e-23 81.9 0.4 7.1e-23 81.0 0.4 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 RLN47476.1 - 1.8e-20 73.1 0.0 0.0053 17.0 0.0 8.9 3 2 6 10 10 10 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN47476.1 - 1.1e-07 31.1 0.1 0.29 10.0 0.1 4.7 3 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RLN47476.1 - 2.8e-06 26.3 0.0 0.016 13.9 0.0 3.3 1 1 3 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.11 RLN47476.1 - 3.3e-05 23.9 0.0 2.3 8.1 0.0 4.3 3 1 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 RLN47476.1 - 0.00012 20.7 0.4 0.54 8.7 0.1 3.5 3 1 0 3 3 3 2 Cytochrome D1 heme domain Proteasome_A_N PF10584.9 RLN47476.1 - 0.0011 18.7 0.6 0.66 9.7 0.0 4.3 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature PD40 PF07676.12 RLN47476.1 - 0.0024 17.7 2.0 32 4.6 0.0 6.2 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 RLN47476.1 - 0.0039 16.6 0.1 1.8 7.9 0.0 3.8 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.9 RLN47476.1 - 0.022 14.5 2.5 4.4 7.0 0.0 4.4 4 1 1 5 5 5 0 Lipoprotein LpqB beta-propeller domain Utp21 PF04192.12 RLN47476.1 - 0.024 14.1 2.3 0.13 11.8 0.1 2.6 3 0 0 3 3 3 0 Utp21 specific WD40 associated putative domain RNA_pol_Rpc34 PF05158.12 RLN47477.1 - 2.9e-51 174.8 0.2 2.1e-48 165.4 0.2 2.8 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit HxlR PF01638.17 RLN47477.1 - 0.037 13.9 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix B-block_TFIIIC PF04182.12 RLN47477.1 - 0.15 12.2 0.1 0.45 10.7 0.1 1.7 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC ABC_trans_N PF14510.6 RLN47526.1 - 0.016 15.8 0.8 14 6.4 1.1 2.8 2 0 0 2 2 2 0 ABC-transporter N-terminal PCAF_N PF06466.11 RLN47526.1 - 0.08 12.5 1.2 0.15 11.6 1.2 1.4 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain DivIC PF04977.15 RLN47526.1 - 0.4 10.5 5.2 0.32 10.8 1.6 2.4 2 0 0 2 2 2 0 Septum formation initiator CALM_bind PF16025.5 RLN47526.1 - 0.59 10.6 9.5 0.47 10.9 5.1 2.6 2 0 0 2 2 2 0 Calcium-dependent calmodulin binding DUF4407 PF14362.6 RLN47526.1 - 2.1 7.6 7.7 3.5 6.9 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.12 RLN47527.1 - 0.32 9.5 5.9 0.51 8.8 5.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family CALM_bind PF16025.5 RLN47527.1 - 1.3 9.6 10.8 4.2 7.9 8.4 2.6 1 1 1 2 2 2 0 Calcium-dependent calmodulin binding Atg14 PF10186.9 RLN47527.1 - 1.3 8.0 5.6 1.9 7.5 5.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MutS_IV PF05190.18 RLN47527.1 - 4.7 7.6 6.6 3.1 8.2 1.4 3.0 3 0 0 3 3 3 0 MutS family domain IV DDE_1 PF03184.19 RLN47528.1 - 5.3e-15 55.5 0.0 9e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 RLN47528.1 - 1.8e-06 27.8 0.0 2e-05 24.4 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease Cellulase PF00150.18 RLN47529.1 - 1e-21 77.6 2.9 2e-21 76.7 2.9 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 RLN47529.1 - 0.02 14.0 0.1 0.035 13.2 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 RLN47529.1 - 0.071 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Beta-galactosidase DUF2967 PF11179.8 RLN47530.1 - 0.02 13.1 2.9 0.025 12.7 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Zip PF02535.22 RLN47530.1 - 0.058 12.6 1.2 0.051 12.8 1.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CAML PF14963.6 RLN47530.1 - 0.13 12.4 0.3 0.16 12.1 0.3 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand AvrPtoB_bdg PF16847.5 RLN47531.1 - 0.04 14.4 0.0 0.12 12.9 0.0 1.7 1 1 0 1 1 1 0 Avirulence AvrPtoB, BAK1-binding domain Ank_4 PF13637.6 RLN47532.1 - 4.9e-17 62.1 3.2 4.9e-07 30.2 0.1 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN47532.1 - 6.6e-15 55.5 1.1 2e-07 31.5 0.1 3.0 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN47532.1 - 9.3e-11 41.8 10.0 0.015 15.6 0.0 6.3 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN47532.1 - 1.5e-06 28.1 0.9 24 5.9 0.0 5.8 5 0 0 5 5 5 1 Ankyrin repeat Cue1_U7BR PF18499.1 RLN47532.1 - 0.2 11.7 0.9 0.5 10.4 0.9 1.6 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 FlaC_arch PF05377.11 RLN47532.1 - 5.3 7.5 5.5 41 4.7 0.2 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Ank_4 PF13637.6 RLN47533.1 - 2.4e-21 75.8 8.0 7.6e-08 32.7 0.1 5.0 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN47533.1 - 1.2e-19 70.7 2.8 2e-08 34.7 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN47533.1 - 5.5e-18 64.8 14.4 0.0021 18.3 0.1 7.2 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN47533.1 - 3.1e-11 42.5 3.9 4.3 8.2 0.0 6.8 6 0 0 6 6 6 3 Ankyrin repeat DUF5049 PF16468.5 RLN47533.1 - 0.00058 19.7 0.0 35 4.4 0.0 4.6 3 1 2 5 5 5 0 Domain of unknown function (DUF5049) Ank PF00023.30 RLN47533.1 - 0.0019 18.5 2.1 27 5.4 0.0 5.2 3 2 0 3 3 3 0 Ankyrin repeat DUF3322 PF11795.8 RLN47533.1 - 0.013 15.5 2.4 0.91 9.5 0.0 3.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) DUF1843 PF08898.10 RLN47533.1 - 0.047 14.2 2.7 11 6.6 0.1 4.3 4 1 0 4 4 4 0 Domain of unknown function (DUF1843) TruB_C_2 PF16198.5 RLN47533.1 - 0.077 13.2 0.1 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 tRNA pseudouridylate synthase B C-terminal domain His_leader PF08047.11 RLN47534.1 - 0.17 11.9 0.5 0.17 11.9 0.5 2.0 2 0 0 2 2 2 0 Histidine operon leader peptide SR-25 PF10500.9 RLN47535.1 - 0.013 15.1 0.8 0.02 14.5 0.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Nmad5 PF18757.1 RLN47538.1 - 0.0074 16.5 0.1 0.0074 16.5 0.1 1.7 2 0 0 2 2 2 1 Nucleotide modification associated domain 5 MEDS PF14417.6 RLN47538.1 - 0.11 12.3 1.8 0.28 11.0 1.8 1.7 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain p31comet PF06581.12 RLN47538.1 - 0.12 11.5 0.1 0.25 10.5 0.1 1.5 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding eIF3_subunit PF08597.10 RLN47538.1 - 0.56 10.1 5.3 0.85 9.5 5.3 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CCDC-167 PF15188.6 RLN47538.1 - 1.3 9.4 6.9 4.6 7.6 1.5 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 C_LFY_FLO PF17538.2 RLN47540.1 - 0.0063 16.0 0.0 0.021 14.3 0.0 1.7 2 0 0 2 2 2 1 DNA Binding Domain (C-terminal) Leafy/Floricaula SelA PF03841.13 RLN47540.1 - 0.047 12.7 0.2 0.13 11.2 0.0 1.7 2 0 0 2 2 2 0 L-seryl-tRNA selenium transferase bZIP_1 PF00170.21 RLN47540.1 - 0.053 13.6 3.4 0.23 11.6 3.4 2.1 1 0 0 1 1 1 0 bZIP transcription factor ROF PF07073.12 RLN47540.1 - 0.18 12.0 0.1 0.44 10.7 0.1 1.7 1 0 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) TipAS PF07739.13 RLN47540.1 - 0.26 11.8 5.2 1.5 9.4 0.9 2.8 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain IFP_35_N PF07334.13 RLN47540.1 - 0.3 11.2 1.9 0.73 9.9 1.9 1.6 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus M PF02370.16 RLN47540.1 - 0.98 10.2 4.8 3.6 8.5 3.5 2.7 2 0 0 2 2 2 0 M protein repeat SRP72 PF08492.12 RLN47541.1 - 0.0062 16.9 5.4 0.11 12.9 0.6 3.0 3 0 0 3 3 3 1 SRP72 RNA-binding domain Csm1_N PF18504.1 RLN47541.1 - 0.013 15.8 5.9 2.7 8.4 0.2 3.1 2 0 0 2 2 2 0 Csm1 N-terminal domain CALM_bind PF16025.5 RLN47541.1 - 0.31 11.5 15.5 0.57 10.7 6.1 3.4 2 2 0 2 2 2 0 Calcium-dependent calmodulin binding CENP-W PF15510.6 RLN47541.1 - 0.4 10.9 3.7 6.4 7.1 0.3 2.9 2 0 0 2 2 2 0 CENP-W protein AROS PF15684.5 RLN47541.1 - 0.91 10.1 12.4 1.3 9.6 1.3 2.9 2 2 0 2 2 2 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 PspB PF06667.12 RLN47541.1 - 0.95 9.6 7.4 3.4 7.8 0.8 3.5 3 0 0 3 3 3 0 Phage shock protein B Pro-NT_NN PF07421.11 RLN47541.1 - 1.1 9.5 7.2 3.5 7.9 1.2 2.6 2 0 0 2 2 2 0 Neurotensin/neuromedin N precursor DivIC PF04977.15 RLN47541.1 - 1.5 8.6 7.3 4.8 7.0 0.1 2.8 2 0 0 2 2 2 0 Septum formation initiator DUF3280 PF11684.8 RLN47542.1 - 0.0092 16.4 0.8 0.023 15.1 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2380) DUF2255 PF10012.9 RLN47542.1 - 0.088 13.0 0.2 0.24 11.6 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) DUF4337 PF14235.6 RLN47542.1 - 1.2 9.3 3.5 2.5 8.2 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) bZIP_1 PF00170.21 RLN47542.1 - 1.3 9.2 13.2 0.03 14.4 5.7 2.1 3 0 0 3 3 3 0 bZIP transcription factor bZIP_1 PF00170.21 RLN47543.1 - 0.39 10.9 5.1 0.83 9.8 5.1 1.5 1 0 0 1 1 1 0 bZIP transcription factor THOC7 PF05615.13 RLN47544.1 - 0.27 11.5 5.1 0.18 12.1 1.6 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 DivIC PF04977.15 RLN47544.1 - 0.5 10.2 2.6 4 7.3 0.5 2.5 2 0 0 2 2 2 0 Septum formation initiator Pkip-1 PF06878.11 RLN47545.1 - 0.37 10.9 6.0 0.79 9.8 1.6 2.7 3 0 0 3 3 3 0 Pkip-1 protein Peptidase_C48 PF02902.19 RLN47548.1 - 1.3e-11 44.8 0.1 1.7e-10 41.1 0.1 2.4 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Pkinase PF00069.25 RLN47549.1 - 4e-66 223.1 0.0 5.4e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN47549.1 - 1.5e-35 122.8 0.0 2.3e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN47549.1 - 9.2e-06 24.7 0.0 2.3e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase PH PF00169.29 RLN47549.1 - 1.2e-05 25.8 0.0 0.00032 21.2 0.0 2.6 1 1 0 1 1 1 1 PH domain APH PF01636.23 RLN47549.1 - 0.0035 17.3 0.8 0.014 15.3 0.8 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 RLN47549.1 - 0.0066 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 RLN47549.1 - 0.028 13.8 0.1 0.052 12.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_11 PF15413.6 RLN47549.1 - 0.075 13.5 0.0 0.27 11.7 0.0 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain Aconitase PF00330.20 RLN47550.1 - 7.3e-65 219.7 0.8 4.1e-63 214.0 0.8 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) GFO_IDH_MocA PF01408.22 RLN47551.1 - 1.4e-20 74.3 0.1 2.5e-20 73.5 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 RLN47551.1 - 9.4e-06 25.6 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 RLN47551.1 - 0.035 14.8 0.0 0.062 14.0 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain F-box PF00646.33 RLN47552.1 - 0.016 15.0 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 F-box domain Spindle_Spc25 PF08234.12 RLN47552.1 - 0.024 14.9 0.2 0.17 12.1 0.1 2.7 1 1 0 1 1 1 0 Chromosome segregation protein Spc25 zinc_ribbon_9 PF14369.6 RLN47552.1 - 0.081 13.2 0.2 0.21 11.9 0.2 1.7 1 0 0 1 1 1 0 zinc-ribbon zf-C2HC_2 PF13913.6 RLN47552.1 - 0.083 12.8 1.9 0.16 11.9 1.9 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Dermcidin PF15291.6 RLN47552.1 - 0.17 12.4 2.8 0.22 12.1 0.2 2.4 2 0 0 2 2 2 0 Dermcidin, antibiotic peptide ABC_tran PF00005.27 RLN47563.1 - 6e-16 59.2 0.0 1e-15 58.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 RLN47563.1 - 1.9e-07 30.7 5.0 2.7e-07 30.2 5.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_16 PF13191.6 RLN47563.1 - 0.00024 21.5 0.0 0.00089 19.7 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 RLN47563.1 - 0.0012 18.2 0.0 0.0024 17.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin DUF815 PF05673.13 RLN47563.1 - 0.008 15.4 0.0 0.022 13.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 RLN47563.1 - 0.017 14.9 0.3 0.036 13.8 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN47563.1 - 0.03 14.6 0.0 0.058 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RLN47563.1 - 0.042 13.7 0.2 0.096 12.6 0.1 1.5 1 1 0 1 1 1 0 RsgA GTPase G-alpha PF00503.20 RLN47563.1 - 0.044 12.9 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_25 PF13481.6 RLN47563.1 - 0.11 12.1 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 RLN47563.1 - 0.13 12.3 0.1 0.3 11.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Cation_ATPase_C PF00689.21 RLN47564.1 - 1.3e-46 158.6 1.1 1.3e-46 158.6 1.1 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 RLN47564.1 - 5.5e-32 110.8 3.2 6.4e-22 77.9 0.9 3.6 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase PF13246.6 RLN47564.1 - 1.7e-18 66.5 0.1 3.6e-18 65.4 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RLN47564.1 - 5.5e-13 49.7 0.8 1.8e-11 44.7 0.8 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RLN47564.1 - 1.2e-10 40.9 0.0 2.9e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RLN47564.1 - 0.00039 20.2 0.7 0.0027 17.5 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4064 PF13273.6 RLN47564.1 - 0.47 10.7 10.8 1.6 9.1 0.1 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) SPX PF03105.19 RLN47565.1 - 1.1e-07 32.2 1.1 2.7e-07 30.9 0.2 2.0 1 1 1 2 2 2 1 SPX domain CCDC154 PF15450.6 RLN47565.1 - 0.009 14.6 0.2 0.012 14.2 0.2 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 YPEB PF14620.6 RLN47565.1 - 0.014 14.8 1.0 0.069 12.5 1.0 1.8 1 1 0 1 1 1 0 YpeB sporulation Mt_ATP_synt PF15704.5 RLN47565.1 - 0.047 13.6 0.1 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 Mitochondrial ATP synthase subunit DUF5315 PF17242.2 RLN47565.1 - 0.16 11.8 1.1 0.99 9.3 0.1 2.3 2 0 0 2 2 2 0 Disordered region of unknown function (DUF5315) SMC_N PF02463.19 RLN47566.1 - 0.12 11.7 0.7 0.15 11.5 0.7 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Bacillus_HBL PF05791.11 RLN47581.1 - 0.00018 21.4 1.2 0.00043 20.2 0.4 1.7 1 1 1 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) SlyX PF04102.12 RLN47581.1 - 0.00052 20.6 4.7 0.021 15.4 0.4 2.9 1 1 2 3 3 3 1 SlyX Spc7 PF08317.11 RLN47581.1 - 0.0026 16.7 6.4 0.0042 16.0 6.4 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Fib_alpha PF08702.10 RLN47581.1 - 0.0049 17.1 7.4 0.0099 16.1 7.4 1.5 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family MbeD_MobD PF04899.12 RLN47581.1 - 0.0052 16.9 0.4 0.027 14.6 0.2 2.1 1 1 1 2 2 2 1 MbeD/MobD like HIP1_clath_bdg PF16515.5 RLN47581.1 - 0.0098 16.5 4.8 0.0098 16.5 4.8 1.9 2 1 0 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 EzrA PF06160.12 RLN47581.1 - 0.028 12.6 5.6 0.046 11.9 0.2 2.4 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Wtap PF17098.5 RLN47581.1 - 0.043 13.8 2.8 0.16 11.9 2.8 2.0 1 1 0 1 1 1 0 WTAP/Mum2p family ATP-grasp_2 PF08442.10 RLN47581.1 - 0.057 13.0 0.4 0.088 12.4 0.4 1.3 1 0 0 1 1 1 0 ATP-grasp domain FlaC_arch PF05377.11 RLN47581.1 - 0.063 13.7 6.5 0.98 9.9 0.2 3.6 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF4618 PF15397.6 RLN47581.1 - 0.081 12.3 7.7 0.13 11.7 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) CENP-F_leu_zip PF10473.9 RLN47581.1 - 0.12 12.4 8.2 0.22 11.5 8.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 RLN47581.1 - 0.16 12.3 4.1 0.38 11.1 3.7 1.8 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 RLN47581.1 - 0.29 11.2 5.6 0.23 11.5 2.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc24 PF08286.11 RLN47581.1 - 0.34 11.2 3.3 0.27 11.5 0.4 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Cnn_1N PF07989.11 RLN47581.1 - 1 9.6 7.7 4.1 7.6 4.1 2.9 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 LRS4 PF10422.9 RLN47581.1 - 1 8.9 8.1 3.7 7.1 6.2 2.2 1 1 1 2 2 2 0 Monopolin complex subunit LRS4 DUF16 PF01519.16 RLN47581.1 - 1.8 9.1 7.4 3.7 8.1 2.9 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 Syntaxin-6_N PF09177.11 RLN47581.1 - 5.7 7.6 7.7 1.5 9.4 2.8 2.5 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Rax2 PF12768.7 RLN47582.1 - 0.0011 18.5 3.3 0.013 14.9 0.0 2.9 3 0 0 3 3 3 1 Cortical protein marker for cell polarity Phage_holin_2_1 PF04971.12 RLN47582.1 - 0.092 12.8 0.3 0.22 11.5 0.3 1.7 1 0 0 1 1 1 0 Bacteriophage P21 holin S WD40 PF00400.32 RLN47592.1 - 4.4e-10 40.0 4.7 0.00066 20.4 0.0 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat DDE_Tnp_4 PF13359.6 RLN47593.1 - 4.7e-26 91.4 0.0 6.6e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 RLN47593.1 - 0.00034 20.3 0.1 0.00098 18.8 0.1 1.8 1 1 0 1 1 1 1 Plant transposon protein GEN1_C PF18380.1 RLN47593.1 - 0.15 13.0 7.7 0.11 13.4 2.8 2.3 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain DUF883 PF05957.13 RLN47593.1 - 0.71 10.5 5.3 1.4 9.6 0.6 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) 2-Hacid_dh_C PF02826.19 RLN47594.1 - 1.7e-41 141.5 0.0 2.3e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 RLN47594.1 - 6.2e-06 26.5 0.0 1.3e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 RLN47594.1 - 0.00026 21.5 0.0 0.00054 20.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 RLN47594.1 - 0.0033 17.5 0.0 0.015 15.3 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 RLN47594.1 - 0.033 14.2 0.1 0.47 10.4 0.1 2.2 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Rossmann-like PF10727.9 RLN47594.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain IlvN PF07991.12 RLN47594.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 RLN47594.1 - 0.2 11.7 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 RLN47594.1 - 0.22 11.4 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Proteasome PF00227.26 RLN47597.1 - 4.9e-50 169.7 0.0 6.6e-50 169.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF3842 PF12953.7 RLN47597.1 - 0.31 11.4 0.2 0.31 11.4 0.2 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3842) HTH_38 PF13936.6 RLN47598.1 - 2e-06 27.4 0.7 5.9e-06 25.9 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 RLN47598.1 - 0.00034 20.3 0.7 0.36 10.7 0.1 2.6 2 1 0 2 2 2 2 Homeodomain-like domain HTH_32 PF13565.6 RLN47598.1 - 0.0038 17.8 2.2 0.012 16.2 0.3 2.5 2 1 1 3 3 3 1 Homeodomain-like domain HTH_Tnp_Tc3_1 PF11427.8 RLN47598.1 - 0.015 15.1 0.3 0.035 13.9 0.3 1.6 1 0 0 1 1 1 0 Tc3 transposase Sec5 PF15469.6 RLN47599.1 - 1.2e-23 84.0 0.0 3.4e-21 75.9 0.0 2.4 1 1 1 2 2 2 2 Exocyst complex component Sec5 PA PF02225.22 RLN47599.1 - 4.4e-07 29.8 0.0 8.8e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 PA domain Occludin_ELL PF07303.13 RLN47599.1 - 0.08 13.7 1.2 11 6.8 0.0 3.1 3 0 0 3 3 3 0 Occludin homology domain Cep57_MT_bd PF06657.13 RLN47599.1 - 0.24 11.9 2.7 56 4.3 0.0 4.1 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Dor1 PF04124.12 RLN47599.1 - 2 7.0 9.5 4.7 5.8 9.0 1.8 1 1 1 2 2 2 0 Dor1-like family SlyX PF04102.12 RLN47599.1 - 4.4 8.0 5.0 5.6 7.7 0.6 3.3 2 2 0 2 2 2 0 SlyX Nup54 PF13874.6 RLN47599.1 - 9.2 6.4 9.8 0.17 12.0 1.7 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 HAD PF12710.7 RLN47601.1 - 9e-09 36.0 0.0 1e-08 35.8 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RLN47601.1 - 2.7e-06 27.8 0.0 2.9e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 RLN47601.1 - 4.2e-05 23.2 0.0 5e-05 22.9 0.0 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) DUF2922 PF11148.8 RLN47601.1 - 0.028 14.1 0.0 0.74 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) SBBP PF06739.11 RLN47601.1 - 0.053 13.5 0.2 0.098 12.7 0.2 1.5 1 0 0 1 1 1 0 Beta-propeller repeat Hydrolase_3 PF08282.12 RLN47601.1 - 0.054 13.2 0.0 0.062 13.0 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 RLN47601.1 - 0.078 13.1 0.0 0.091 12.8 0.0 1.1 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Synaptobrevin PF00957.21 RLN47603.1 - 7.1e-19 67.4 4.6 5.4e-16 58.2 0.4 2.3 2 0 0 2 2 2 2 Synaptobrevin Longin PF13774.6 RLN47603.1 - 2.6e-14 53.0 0.9 4.1e-14 52.4 0.9 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain TMEM43 PF07787.12 RLN47603.1 - 0.003 17.0 0.1 0.0041 16.5 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 43 XFP PF03894.15 RLN47603.1 - 0.063 13.0 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Presenilin PF01080.17 RLN47604.1 - 9.4e-42 143.2 23.9 3.1e-24 85.5 12.6 3.0 2 1 1 3 3 3 3 Presenilin DUF997 PF06196.12 RLN47604.1 - 4.8 7.2 10.1 8.9 6.4 4.8 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF997) PAN_1 PF00024.26 RLN47605.1 - 4.1e-06 26.7 2.5 7.9e-06 25.8 2.5 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 RLN47605.1 - 0.0072 16.2 1.6 0.015 15.2 1.6 1.5 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 RLN47605.1 - 0.024 14.7 3.3 0.043 13.9 3.3 1.5 1 0 0 1 1 1 0 PAN-like domain Ribosomal_L7Ae PF01248.26 RLN47606.1 - 8e-26 89.6 0.4 1.2e-25 89.1 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Pkinase PF00069.25 RLN47607.1 - 2.8e-54 184.2 0.1 1e-53 182.4 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN47607.1 - 1.2e-22 80.4 0.0 2.3e-20 73.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Choline_kinase PF01633.20 RLN47607.1 - 4.2e-05 23.2 0.1 0.00065 19.3 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 RLN47607.1 - 0.016 15.1 0.0 0.05 13.5 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF1308 PF07000.11 RLN47607.1 - 0.07 13.1 0.0 5.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1308) ABC1 PF03109.16 RLN47607.1 - 0.13 12.4 0.1 0.33 11.1 0.1 1.6 1 0 0 1 1 1 0 ABC1 family Allantoicase PF03561.15 RLN47608.1 - 1.4e-87 291.0 0.0 8.3e-44 149.1 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat DUF512 PF04459.12 RLN47608.1 - 0.078 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF512) HIG_1_N PF04588.13 RLN47610.1 - 1.6e-16 60.3 1.7 2.6e-16 59.6 1.7 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region WD40 PF00400.32 RLN47611.1 - 1.5e-11 44.7 8.5 4.4e-05 24.1 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN47611.1 - 3.2e-06 27.3 0.0 0.41 11.0 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 RLN47611.1 - 0.019 15.5 0.2 0.28 11.7 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain TPR_14 PF13428.6 RLN47612.1 - 1.9e-32 109.2 27.9 0.00012 22.6 0.3 13.3 4 2 11 15 15 14 6 Tetratricopeptide repeat TPR_2 PF07719.17 RLN47612.1 - 2.2e-30 102.3 13.7 0.0041 17.1 0.1 13.3 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_19 PF14559.6 RLN47612.1 - 2.1e-26 92.2 4.9 4.9e-06 27.0 0.2 7.6 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 RLN47612.1 - 1.1e-19 70.8 30.6 0.00025 21.6 1.2 8.6 6 1 2 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.6 RLN47612.1 - 5.8e-19 68.2 11.8 0.0044 17.3 0.0 9.0 5 3 3 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 RLN47612.1 - 9.9e-19 66.3 1.0 0.065 13.6 0.0 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.6 RLN47612.1 - 1.7e-15 56.5 4.4 1.4 9.7 0.1 11.3 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN47612.1 - 2e-15 55.7 0.6 0.028 14.6 0.0 8.7 11 0 0 11 11 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN47612.1 - 4.8e-13 48.3 6.7 0.033 14.0 0.0 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN47612.1 - 3.9e-10 39.7 15.3 0.0021 18.2 0.8 7.3 3 2 2 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN47612.1 - 2.3e-09 36.8 0.0 0.019 14.6 0.0 4.9 5 0 0 5 5 4 2 TPR repeat ANAPC3 PF12895.7 RLN47612.1 - 1.4e-08 34.8 1.5 0.069 13.4 0.0 4.9 4 1 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 RLN47612.1 - 2.2e-06 27.3 3.6 0.0053 16.2 2.3 2.7 1 1 1 2 2 2 2 MalT-like TPR region Suf PF05843.14 RLN47612.1 - 2.3e-06 27.9 0.7 0.2 11.6 0.0 3.7 3 2 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_7 PF13176.6 RLN47612.1 - 5e-05 23.0 4.9 0.49 10.5 0.0 5.4 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_3 PF07720.12 RLN47612.1 - 0.017 15.1 0.0 0.063 13.3 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_20 PF14561.6 RLN47612.1 - 0.034 14.5 7.4 0.47 10.8 0.0 4.3 4 2 0 4 4 4 0 Tetratricopeptide repeat NARP1 PF12569.8 RLN47612.1 - 0.054 12.4 8.0 0.14 11.1 0.0 3.6 3 1 1 4 4 4 0 NMDA receptor-regulated protein 1 Tcf25 PF04910.14 RLN47612.1 - 0.16 11.1 1.3 6 5.8 0.1 3.0 2 1 0 3 3 3 0 Transcriptional repressor TCF25 Fis1_TPR_C PF14853.6 RLN47612.1 - 0.75 9.9 5.6 1e+02 3.1 0.0 5.8 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 RLN47612.1 - 1.7 8.6 16.0 8.6 6.4 0.0 6.8 8 1 0 9 9 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 RLN47612.1 - 2.3 9.1 25.5 0.36 11.6 1.7 7.3 8 0 0 8 8 6 0 Tetratricopeptide repeat SMBP PF16785.5 RLN47612.1 - 5.5 7.2 10.9 1.5 9.1 0.1 4.6 5 0 0 5 5 5 0 Small metal-binding protein FAT PF02259.23 RLN47612.1 - 6.7 5.8 9.4 3.5 6.7 1.0 3.4 2 2 1 3 3 3 0 FAT domain Carb_anhydrase PF00194.21 RLN47623.1 - 3.5e-30 105.4 0.0 5.6e-30 104.7 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Cnd1 PF12717.7 RLN47625.1 - 3e-45 154.2 1.2 1.9e-43 148.3 0.1 3.8 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RLN47625.1 - 0.00056 20.2 0.2 0.078 13.4 0.0 4.0 4 0 0 4 4 4 1 HEAT repeats Adaptin_N PF01602.20 RLN47625.1 - 0.00092 17.9 3.6 0.0012 17.5 0.1 2.9 3 1 0 3 3 3 1 Adaptin N terminal region Cnd1_N PF12922.7 RLN47625.1 - 0.016 15.1 0.0 0.016 15.1 0.0 2.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 RLN47625.1 - 0.039 14.2 2.0 6.9 7.2 0.2 4.7 4 0 0 4 4 4 0 HEAT repeat Cnd3 PF12719.7 RLN47625.1 - 0.18 11.0 5.2 0.15 11.2 0.3 3.3 4 1 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain Ribosomal_60s PF00428.19 RLN47626.1 - 0.037 14.6 6.5 0.052 14.1 6.5 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein PBP1_TM PF14812.6 RLN47626.1 - 0.55 10.6 3.7 0.76 10.2 3.7 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 RLN47626.1 - 1.2 8.4 5.9 1.4 8.1 5.9 1.1 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 RLN47626.1 - 2.8 8.4 10.7 4.8 7.6 10.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 RLN47626.1 - 5.5 5.0 7.7 5.7 4.9 7.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi Bd3614-deam PF14439.6 RLN47627.1 - 0.75 9.9 6.7 32 4.6 0.6 3.8 1 1 2 3 3 3 0 Bd3614-like deaminase DUF1375 PF07119.12 RLN47628.1 - 0.12 12.8 1.0 4.1 7.9 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1375) DUF1375 PF07119.12 RLN47630.1 - 0.1 13.0 1.0 3.8 8.0 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1375) Glyco_transf_20 PF00982.21 RLN47631.1 - 2.9e-134 448.3 0.0 3.6e-134 448.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 RLN47631.1 - 1.3e-35 122.6 0.0 4e-29 101.4 0.0 2.3 2 0 0 2 2 2 2 Trehalose-phosphatase Glycos_transf_1 PF00534.20 RLN47631.1 - 0.0095 15.5 0.0 0.23 11.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Baculo_PEP_C PF04513.12 RLN47639.1 - 0.0096 16.0 0.2 0.01 15.9 0.2 1.0 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 RLN47639.1 - 0.041 14.0 0.5 0.046 13.8 0.5 1.0 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Scm3 PF10384.9 RLN47639.1 - 0.041 13.6 0.0 0.052 13.3 0.0 1.1 1 0 0 1 1 1 0 Centromere protein Scm3 LppA PF16708.5 RLN47639.1 - 0.042 13.8 1.0 0.04 13.9 1.0 1.0 1 0 0 1 1 1 0 Lipoprotein confined to pathogenic Mycobacterium DUF948 PF06103.11 RLN47639.1 - 0.091 13.0 0.9 0.096 13.0 0.9 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Snf7 PF03357.21 RLN47639.1 - 0.12 12.0 7.7 0.12 11.9 7.7 1.0 1 0 0 1 1 1 0 Snf7 COMP PF11598.8 RLN47639.1 - 0.17 12.4 2.2 0.31 11.5 1.8 1.6 1 1 1 2 2 2 0 Cartilage oligomeric matrix protein HalX PF08663.10 RLN47639.1 - 0.3 11.4 4.9 2.1 8.7 4.9 1.9 1 1 0 1 1 1 0 HalX domain Peptidase_M20 PF01546.28 RLN47650.1 - 3.2e-36 125.0 0.0 4.1e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 RLN47650.1 - 0.00031 20.5 0.0 0.028 14.1 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M28 Peptidase_M20 PF01546.28 RLN47651.1 - 2.5e-35 122.1 0.0 3.2e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 RLN47651.1 - 2.8e-09 36.9 0.0 4.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 RLN47651.1 - 3.4e-07 30.2 0.0 5.5e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M28 Sulfate_transp PF00916.20 RLN47652.1 - 1.9e-74 250.8 26.0 4.6e-40 137.6 0.9 3.3 3 0 0 3 3 3 2 Sulfate permease family ABC2_membrane PF01061.24 RLN47652.1 - 8.4e-29 100.5 29.9 8.4e-29 100.5 29.9 3.8 4 0 0 4 4 4 1 ABC-2 type transporter STAS PF01740.21 RLN47652.1 - 9.1e-09 35.0 0.0 1.8e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 STAS domain PDR_CDR PF06422.12 RLN47652.1 - 1.7e-07 31.0 0.0 7.6e-07 29.0 0.0 2.2 1 0 0 1 1 1 1 CDR ABC transporter MFS_MOT1 PF16983.5 RLN47652.1 - 0.0013 19.1 4.8 0.0013 19.1 4.8 4.1 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 RLN47652.1 - 0.11 12.9 0.2 0.28 11.5 0.2 1.7 1 0 0 1 1 1 0 STAS domain TIR_2 PF13676.6 RLN47657.1 - 2.6e-34 118.4 0.0 3.5e-18 66.3 0.0 2.2 2 0 0 2 2 2 2 TIR domain TIR PF01582.20 RLN47657.1 - 2.2e-10 40.6 0.0 4.3e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 TIR domain DUF1863 PF08937.11 RLN47657.1 - 1e-06 29.1 0.0 0.011 16.0 0.3 3.4 2 1 0 2 2 2 2 MTH538 TIR-like domain (DUF1863) HGTP_anticodon PF03129.20 RLN47657.1 - 0.087 13.0 0.0 10 6.4 0.0 2.8 2 0 0 2 2 2 0 Anticodon binding domain DUF572 PF04502.13 RLN47658.1 - 0.012 15.3 1.6 0.015 15.0 1.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Cwf_Cwc_15 PF04889.12 RLN47658.1 - 0.091 12.5 14.0 0.12 12.1 14.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SGT1 PF07093.11 RLN47658.1 - 0.19 10.1 3.3 0.2 10.1 3.3 1.1 1 0 0 1 1 1 0 SGT1 protein RRN3 PF05327.11 RLN47658.1 - 0.21 10.1 11.1 0.25 9.8 11.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GCIP PF13324.6 RLN47658.1 - 0.21 11.2 8.3 0.26 10.8 8.3 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting YL1 PF05764.13 RLN47658.1 - 0.48 10.5 8.3 0.55 10.3 8.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein NOA36 PF06524.12 RLN47658.1 - 0.69 9.2 15.5 0.96 8.7 15.5 1.1 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.10 RLN47658.1 - 0.79 9.0 9.0 0.85 8.9 9.0 1.1 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.14 RLN47658.1 - 0.86 9.4 5.4 1.2 8.8 5.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 RLN47658.1 - 0.86 7.7 8.3 0.85 7.8 8.3 1.0 1 0 0 1 1 1 0 Nop14-like family Pes-10 PF07149.11 RLN47658.1 - 0.93 8.5 8.2 1.1 8.2 8.2 1.1 1 0 0 1 1 1 0 Pes-10 DNA_pol_phi PF04931.13 RLN47658.1 - 1.1 7.3 13.7 1 7.4 13.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi PGA2 PF07543.12 RLN47658.1 - 1.4 8.9 5.6 2.4 8.1 5.6 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 CDC45 PF02724.14 RLN47658.1 - 2.2 6.5 9.4 2.6 6.2 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 RLN47658.1 - 2.4 7.2 19.4 3.1 6.9 19.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Macro PF01661.21 RLN47661.1 - 1.4e-14 54.1 0.0 2.4e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Macro domain Ank_2 PF12796.7 RLN47663.1 - 6.3e-28 97.2 6.4 8.4e-08 32.7 0.2 4.9 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN47663.1 - 1.7e-23 82.6 15.4 2.9e-05 24.5 0.1 8.4 4 3 3 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN47663.1 - 2.9e-21 75.3 14.0 7.3e-05 23.0 0.1 9.2 2 1 8 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN47663.1 - 6e-17 60.0 3.3 2 9.3 0.0 10.8 11 1 1 12 12 12 3 Ankyrin repeat DUF5049 PF16468.5 RLN47663.1 - 2e-07 30.8 0.2 2.1 8.3 0.0 6.4 3 3 4 7 7 7 1 Domain of unknown function (DUF5049) Ank PF00023.30 RLN47663.1 - 2.1e-07 31.0 2.9 3.8 8.1 0.0 7.2 4 2 2 6 6 6 2 Ankyrin repeat DUF3322 PF11795.8 RLN47663.1 - 0.00014 22.0 2.0 0.49 10.4 0.0 4.7 2 1 3 5 5 5 1 Uncharacterized protein conserved in bacteria N-term (DUF3322) FBD PF08387.10 RLN47663.1 - 0.00037 20.3 0.1 49 3.9 0.0 5.3 6 0 0 6 6 6 0 FBD DUF1979 PF09322.10 RLN47663.1 - 0.017 15.0 0.2 14 5.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1979) DUF4411 PF14367.6 RLN47663.1 - 0.12 12.3 0.1 12 5.7 0.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4411) HOIP-UBA PF16678.5 RLN47663.1 - 0.15 12.1 2.0 1.5 8.8 0.0 3.4 4 1 1 5 5 5 0 HOIP UBA domain pair UPF0489 PF12640.7 RLN47663.1 - 0.16 12.2 2.8 3 8.0 0.6 3.2 2 2 0 2 2 2 0 UPF0489 domain bPH_1 PF08000.11 RLN47664.1 - 4.6e-18 65.5 0.0 8.4e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial PH domain Macro PF01661.21 RLN47664.1 - 4e-16 59.1 0.0 8.7e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Macro domain RP-C_C PF11800.8 RLN47664.1 - 0.00083 19.5 1.7 0.0021 18.2 1.7 1.7 1 0 0 1 1 1 1 Replication protein C C-terminal region Tim54 PF11711.8 RLN47664.1 - 0.0021 16.9 1.3 0.0021 16.9 1.3 1.5 2 0 0 2 2 2 1 Inner membrane protein import complex subunit Tim54 Sporozoite_P67 PF05642.11 RLN47664.1 - 0.0033 15.6 2.3 0.0063 14.7 2.3 1.4 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Nop14 PF04147.12 RLN47664.1 - 0.029 12.6 11.2 0.041 12.1 11.2 1.1 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 RLN47664.1 - 0.087 13.1 14.1 0.18 12.1 14.1 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF4637 PF15470.6 RLN47664.1 - 0.11 12.2 11.3 0.29 10.8 11.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) ECSIT_C PF14784.6 RLN47664.1 - 0.14 12.5 1.4 0.41 11.0 1.4 1.7 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein BUD22 PF09073.10 RLN47664.1 - 1.1 8.5 13.4 1.8 7.8 13.4 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 RLN47664.1 - 1.5 8.2 16.5 2.3 7.6 16.5 1.1 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 RLN47664.1 - 9.3 5.5 18.4 16 4.8 18.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mto2_bdg PF12808.7 RLN47665.1 - 0.052 13.9 9.6 1.2 9.5 2.9 2.5 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region NA37 PF04245.13 RLN47665.1 - 0.16 11.4 1.4 0.27 10.7 1.4 1.3 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein DUF4598 PF15370.6 RLN47665.1 - 0.26 11.8 2.9 0.49 10.9 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4598) HLH PF00010.26 RLN47666.1 - 3.5e-08 33.3 6.3 6e-08 32.5 6.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SR-25 PF10500.9 RLN47666.1 - 9.4 5.8 8.4 0.19 11.3 1.0 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein XRN_N PF03159.18 RLN47667.1 - 2e-86 289.4 0.0 2.8e-86 288.9 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 RLN47667.1 - 6.8e-29 101.1 0.0 9.2e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Xrn1 helical domain DDE_3 PF13358.6 RLN47672.1 - 7.4e-13 48.5 0.0 1.8e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 RLN47672.1 - 1.1e-05 26.0 0.0 2.8e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 RLN47672.1 - 7.8e-05 22.4 0.9 0.00015 21.4 0.2 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 RLN47672.1 - 0.00019 21.5 0.5 0.00041 20.4 0.5 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 RLN47672.1 - 0.012 15.9 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 Transposase DEAD PF00270.29 RLN47672.1 - 0.028 14.2 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN47672.1 - 0.039 14.3 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 Helicase conserved C-terminal domain AP_endonuc_2 PF01261.24 RLN47673.1 - 5.2e-06 26.1 0.0 1.6e-05 24.4 0.0 1.7 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel KNOX2 PF03791.13 RLN47673.1 - 0.04 13.4 0.0 0.081 12.4 0.0 1.5 1 0 0 1 1 1 0 KNOX2 domain FSA_C PF10479.9 RLN47674.1 - 0.1 10.7 4.3 0.096 10.8 4.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Dicty_REP PF05086.12 RLN47674.1 - 0.57 8.1 1.7 0.62 8.0 1.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.8 RLN47674.1 - 1.6 8.7 10.5 2.4 8.1 10.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 RLN47674.1 - 3.3 5.8 12.8 3.7 5.6 12.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Clat_adaptor_s PF01217.20 RLN47675.1 - 4.6e-52 175.7 0.8 5e-52 175.6 0.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain NUFIP1 PF10453.9 RLN47676.1 - 2.6e-08 33.6 0.1 6e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCHC_2 PF13696.6 RLN47676.1 - 1.5e-06 27.9 11.2 3e-06 26.9 11.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCCH_4 PF18044.1 RLN47676.1 - 0.00019 21.1 10.3 0.062 13.1 1.1 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 RLN47676.1 - 0.00081 19.4 1.2 0.00081 19.4 1.2 2.9 3 0 0 3 3 3 1 Zinc finger domain zf-C2H2 PF00096.26 RLN47676.1 - 0.0014 18.9 0.3 0.0014 18.9 0.3 2.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-CCCH PF00642.24 RLN47676.1 - 0.0028 17.5 13.5 0.047 13.6 2.2 3.0 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2719 PF10891.8 RLN47676.1 - 0.01 15.7 0.1 0.022 14.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2719) zf-CCHC PF00098.23 RLN47676.1 - 0.011 15.8 4.4 0.011 15.8 4.4 2.1 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 RLN47676.1 - 0.011 15.6 1.9 0.011 15.6 1.9 2.0 2 0 0 2 2 1 0 Zinc knuckle zf-C2H2_jaz PF12171.8 RLN47676.1 - 0.017 15.4 2.1 0.042 14.1 2.1 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Torus PF16131.5 RLN47676.1 - 0.045 14.4 1.8 0.1 13.3 1.8 1.6 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 RLN47676.1 - 0.17 12.4 8.8 1.7 9.3 0.7 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DUF4379 PF14311.6 RLN47676.1 - 0.29 11.5 6.4 0.16 12.3 2.9 2.4 2 0 0 2 2 2 0 Probable Zinc-ribbon domain zf-met PF12874.7 RLN47676.1 - 0.8 10.2 5.3 0.11 13.0 1.0 1.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type C2 PF00168.30 RLN47677.1 - 0.069 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 C2 domain MFS_1 PF07690.16 RLN47725.1 - 1.1e-09 37.7 21.1 1.3e-09 37.4 21.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PglZ PF08665.12 RLN47725.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 PglZ domain MFS_1 PF07690.16 RLN47726.1 - 2.4e-07 30.0 4.0 2.9e-07 29.8 4.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily NQR2_RnfD_RnfE PF03116.15 RLN47726.1 - 0.0049 16.3 3.2 0.0062 16.0 3.2 1.1 1 0 0 1 1 1 1 NQR2, RnfD, RnfE family DUF347 PF03988.12 RLN47726.1 - 0.96 9.7 4.8 1.8 8.8 1.7 2.7 2 1 0 2 2 2 0 Repeat of Unknown Function (DUF347) Slu7 PF11708.8 RLN47728.1 - 4.5e-98 328.3 19.3 4.5e-98 328.3 19.3 2.2 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor DUF4050 PF13259.6 RLN47728.1 - 1.5 9.1 11.4 0.29 11.4 5.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Vfa1 PF08432.10 RLN47728.1 - 1.7 8.9 27.7 0.21 11.9 10.6 3.1 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 FAM60A PF15396.6 RLN47728.1 - 4.1 7.3 15.8 0.21 11.5 4.7 2.6 3 0 0 3 3 3 0 Protein Family FAM60A Bromodomain PF00439.25 RLN47729.1 - 2.6e-86 283.8 0.1 1.7e-18 66.4 0.0 6.6 6 1 0 6 6 6 6 Bromodomain PMM PF03332.13 RLN47730.1 - 2.9e-86 288.8 1.6 3.7e-86 288.5 1.6 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 RLN47730.1 - 0.076 12.7 0.4 0.31 10.7 0.3 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cyclin_N PF00134.23 RLN47731.1 - 5.2e-09 35.9 0.0 1.1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 RLN47731.1 - 0.00061 19.9 0.0 0.0015 18.6 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Transformer PF06495.11 RLN47732.1 - 0.15 12.1 5.2 0.23 11.6 5.2 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein TFIIA PF03153.13 RLN47732.1 - 1.6 8.7 18.5 2.2 8.2 18.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IQ PF00612.27 RLN47733.1 - 0.048 13.5 0.1 0.19 11.6 0.1 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif HA2 PF04408.23 RLN47734.1 - 4.8e-26 91.2 0.2 1.1e-25 90.1 0.2 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RLN47734.1 - 2.6e-19 69.4 0.0 1.2e-18 67.2 0.0 2.2 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 RLN47734.1 - 6.6e-10 39.3 0.0 1.6e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RLN47734.1 - 7.2e-08 32.4 0.3 1.5e-07 31.3 0.3 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 RLN47734.1 - 6.1e-07 28.8 0.0 1.2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 RLN47734.1 - 3.5e-06 27.4 0.2 6.9e-06 26.5 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RLN47734.1 - 1.1e-05 25.7 0.0 3.7e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 RLN47734.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Herpes_ori_bp PF02399.15 RLN47734.1 - 0.0017 16.5 0.0 0.0026 15.9 0.0 1.1 1 0 0 1 1 1 1 Origin of replication binding protein AAA_30 PF13604.6 RLN47734.1 - 0.0027 17.5 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 RLN47734.1 - 0.01 15.1 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 RLN47734.1 - 0.016 14.7 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 RLN47734.1 - 0.025 14.6 0.1 0.54 10.3 0.1 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 RLN47734.1 - 0.035 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Helicase AAA_11 PF13086.6 RLN47734.1 - 0.037 13.8 0.1 0.072 12.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 RLN47734.1 - 0.038 13.7 0.0 0.39 10.4 0.0 2.5 3 0 0 3 3 2 0 Thymidylate kinase NACHT PF05729.12 RLN47734.1 - 0.044 13.7 0.3 0.16 11.8 0.1 2.3 2 1 0 2 2 1 0 NACHT domain Sigma54_activ_2 PF14532.6 RLN47734.1 - 0.044 13.9 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 RLN47734.1 - 0.059 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 RLN47734.1 - 0.063 13.8 0.1 0.25 11.9 0.1 2.1 1 1 0 1 1 1 0 ABC transporter TrwB_AAD_bind PF10412.9 RLN47734.1 - 0.064 12.2 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 RLN47734.1 - 0.068 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 RLN47734.1 - 0.074 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 RLN47734.1 - 0.099 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DAP3 PF10236.9 RLN47734.1 - 0.12 11.6 0.3 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Viral_helicase1 PF01443.18 RLN47734.1 - 0.14 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PIF1 PF05970.14 RLN47734.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase DEAD PF00270.29 RLN47735.1 - 7.6e-37 126.8 0.2 1.1e-36 126.2 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN47735.1 - 6.6e-25 87.6 0.0 5.9e-24 84.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN47735.1 - 1.8e-05 24.8 0.0 3.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 RLN47735.1 - 0.0031 16.7 0.0 0.0059 15.8 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SNF2_N PF00176.23 RLN47735.1 - 0.01 14.6 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.6 RLN47735.1 - 0.074 13.3 0.2 0.42 10.9 0.2 2.2 1 1 0 1 1 1 0 AAA domain NFACT-C PF11923.8 RLN47736.1 - 6.2e-33 112.9 0.0 6.2e-33 112.9 0.0 3.1 4 0 0 4 4 4 1 NFACT protein C-terminal domain FbpA PF05833.11 RLN47736.1 - 8.3e-31 107.2 9.6 8.3e-31 107.2 9.6 2.9 3 1 0 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 RLN47736.1 - 2.8e-30 105.2 0.0 9.4e-30 103.5 0.0 2.0 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF5590 PF17881.1 RLN47736.1 - 0.085 13.0 0.0 0.085 13.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5590) YrhK PF14145.6 RLN47737.1 - 2.5e-32 110.5 28.7 1.7e-13 50.2 5.4 3.2 3 0 0 3 3 3 3 YrhK-like protein DUF3533 PF12051.8 RLN47737.1 - 0.18 10.7 14.1 1.2 8.0 1.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3533) ATP1G1_PLM_MAT8 PF02038.16 RLN47737.1 - 0.31 10.5 4.1 0.51 9.8 0.8 2.7 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Radial_spoke PF04712.12 RLN47738.1 - 5e-10 38.9 0.0 5.3e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 Radial spokehead-like protein Dicer_dimer PF03368.14 RLN47739.1 - 9.8e-21 73.7 0.1 2.2e-20 72.6 0.1 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.29 RLN47739.1 - 2.8e-18 66.3 0.0 4.6e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 RLN47739.1 - 1.2e-12 48.2 0.0 2.4e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RLN47739.1 - 3.8e-08 33.6 0.3 5.7e-07 29.9 0.1 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain IstB_IS21 PF01695.17 RLN47739.1 - 4e-05 23.4 0.0 0.00014 21.6 0.0 1.9 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 RLN47739.1 - 0.0035 17.6 0.0 0.017 15.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 RLN47739.1 - 0.032 14.8 0.0 0.25 11.9 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 RLN47739.1 - 0.039 13.5 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 RLN47739.1 - 0.04 13.4 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 RLN47739.1 - 0.054 13.9 0.0 0.67 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 RLN47739.1 - 0.078 12.7 0.0 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.9 RLN47739.1 - 0.084 12.1 0.0 0.19 10.9 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 RLN47739.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 RLN47739.1 - 0.17 12.2 0.3 1.1 9.6 0.3 2.2 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RLN47739.1 - 0.18 11.7 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase GBP PF02263.19 RLN47740.1 - 1.1e-39 136.3 0.0 2.4e-39 135.1 0.0 1.5 1 1 0 1 1 1 1 Guanylate-binding protein, N-terminal domain OxoGdeHyase_C PF16870.5 RLN47766.1 - 3.4e-20 72.3 0.0 3.7e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal TGase_elicitor PF16683.5 RLN47767.1 - 3.2e-181 601.9 0.5 5.2e-181 601.2 0.5 1.3 1 0 0 1 1 1 1 Transglutaminase elicitor CCDC66 PF15236.6 RLN47768.1 - 0.0014 18.4 6.5 0.0014 18.4 6.5 4.4 3 1 1 4 4 4 2 Coiled-coil domain-containing protein 66 LCD1 PF09798.9 RLN47768.1 - 5.4 5.4 12.8 0.12 10.9 2.1 2.2 2 0 0 2 2 2 0 DNA damage checkpoint protein Pur_ac_phosph_N PF16656.5 RLN47769.1 - 2.4e-18 66.5 4.0 2.4e-18 66.5 4.0 1.9 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 RLN47769.1 - 1.3e-05 25.8 0.0 1.8e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD_N PF16655.5 RLN47769.1 - 0.0037 17.8 0.2 0.0091 16.5 0.2 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Metallophos_2 PF12850.7 RLN47769.1 - 0.085 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF5554 PF17709.1 RLN47769.1 - 0.11 12.6 0.3 0.3 11.2 0.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5554) Ank_2 PF12796.7 RLN47780.1 - 7.8e-12 45.6 0.2 1.1e-05 26.0 0.1 3.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN47780.1 - 2e-05 24.6 2.4 0.43 11.3 0.0 5.4 5 1 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 RLN47780.1 - 2.5e-05 24.7 4.6 0.031 14.9 0.1 4.5 3 1 2 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN47780.1 - 2.7e-05 24.4 1.9 1.6 9.1 0.0 4.7 2 2 3 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN47780.1 - 0.002 18.5 4.2 0.89 10.1 0.2 3.9 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 RLN47781.1 - 8.9e-15 55.1 0.0 1.5e-07 31.9 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN47781.1 - 2.3e-06 28.0 0.2 0.0011 19.4 0.0 3.7 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN47781.1 - 4.3e-06 26.7 0.1 1.3 9.9 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 RLN47781.1 - 0.00015 22.0 0.5 0.16 12.3 0.1 4.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN47781.1 - 0.00068 20.0 0.5 0.073 13.6 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeat FlaF PF07309.11 RLN47781.1 - 0.1 12.6 0.2 0.28 11.2 0.2 1.7 1 0 0 1 1 1 0 Flagellar protein FlaF Palm_thioest PF02089.15 RLN47783.1 - 5e-48 164.1 0.0 6.7e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 RLN47783.1 - 0.00094 18.9 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 RLN47783.1 - 0.009 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 RLN47783.1 - 0.017 15.8 0.3 0.034 14.8 0.3 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 RLN47783.1 - 0.019 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF676 PF05057.14 RLN47783.1 - 0.023 14.2 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 RLN47783.1 - 0.033 13.5 0.0 0.082 12.2 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 CitF PF04223.12 RLN47783.1 - 0.09 11.6 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) DUF3767 PF12597.8 RLN47784.1 - 3.4e-10 39.7 0.1 4.3e-10 39.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) 5TM-5TMR_LYT PF07694.12 RLN47784.1 - 0.022 14.3 0.7 0.026 14.0 0.7 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT Ank_2 PF12796.7 RLN47785.1 - 2.6e-08 34.4 0.0 0.00084 19.9 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Complex1_LYR PF05347.15 RLN47785.1 - 0.00087 19.3 0.1 0.015 15.3 0.1 2.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) KH_1 PF00013.29 RLN47786.1 - 3.6e-63 209.3 13.2 2.9e-18 65.4 0.1 4.2 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 RLN47786.1 - 2.3e-13 49.8 8.4 7.9e-05 22.5 0.1 4.2 4 0 0 4 4 4 3 KH domain KH_2 PF07650.17 RLN47786.1 - 2e-11 43.5 9.3 0.003 17.4 0.0 4.3 4 0 0 4 4 4 4 KH domain KH_5 PF13184.6 RLN47786.1 - 4.8e-05 23.4 3.0 3.7 7.7 0.0 4.3 4 0 0 4 4 4 1 NusA-like KH domain GRP PF07172.11 RLN47786.1 - 2.4 8.9 49.5 2.5 8.9 21.6 3.1 3 0 0 3 3 3 0 Glycine rich protein family Secretin_N PF03958.17 RLN47786.1 - 3.7 8.0 8.0 25 5.4 0.2 4.2 4 0 0 4 4 4 0 Bacterial type II/III secretion system short domain Ras PF00071.22 RLN47789.1 - 5.7e-05 22.8 0.0 6.2e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN47789.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Elicitin PF00964.17 RLN47791.1 - 7.6e-22 77.2 2.3 7.6e-22 77.2 2.3 2.2 2 1 1 3 3 3 2 Elicitin Myb_DNA-bind_7 PF15963.5 RLN47792.1 - 1.8e-24 85.5 0.1 4e-24 84.3 0.1 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 RLN47792.1 - 0.0014 18.8 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain AA_permease_2 PF13520.6 RLN47801.1 - 8.1e-26 90.8 17.1 8.1e-26 90.8 17.1 1.9 2 1 0 2 2 2 1 Amino acid permease EF-hand_7 PF13499.6 RLN47801.1 - 1.2e-15 57.6 1.3 2.3e-09 37.6 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN47801.1 - 1.2e-13 49.6 0.3 0.0017 17.8 0.1 4.8 5 0 0 5 5 5 3 EF hand AA_permease PF00324.21 RLN47801.1 - 4e-12 45.5 18.8 1.5e-11 43.6 13.8 2.6 2 1 1 3 3 3 1 Amino acid permease EF-hand_8 PF13833.6 RLN47801.1 - 6.3e-11 42.0 1.4 8.2e-09 35.2 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN47801.1 - 1.3e-09 37.1 0.2 0.16 12.0 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain AA_permease_C PF13906.6 RLN47801.1 - 2.9e-07 30.4 4.3 2.9e-07 30.4 4.3 2.6 2 0 0 2 2 2 1 C-terminus of AA_permease EF-hand_5 PF13202.6 RLN47801.1 - 4.8e-07 29.0 0.1 0.027 14.0 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_11 PF08976.11 RLN47801.1 - 0.011 16.6 0.0 0.97 10.3 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain BUD22 PF09073.10 RLN47801.1 - 0.034 13.5 4.2 0.047 13.0 4.2 1.1 1 0 0 1 1 1 0 BUD22 zf-C3HC4_2 PF13923.6 RLN47803.1 - 1e-06 28.5 3.2 1e-06 28.5 3.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN47803.1 - 6.6e-06 26.3 3.3 1.3e-05 25.3 0.5 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 RLN47803.1 - 3.7e-05 23.9 1.8 3.7e-05 23.9 1.8 2.6 3 0 0 3 3 2 1 Ring finger domain PX PF00787.24 RLN47803.1 - 3.9e-05 23.6 0.4 8.8e-05 22.5 0.4 1.6 1 0 0 1 1 1 1 PX domain zf-RING_5 PF14634.6 RLN47803.1 - 6.1e-05 22.9 0.9 6.1e-05 22.9 0.9 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RLN47803.1 - 0.00022 21.0 1.4 0.00022 21.0 1.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN47803.1 - 0.0041 16.8 0.4 0.0041 16.8 0.4 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 RLN47803.1 - 0.042 13.9 0.8 0.042 13.9 0.8 2.0 2 0 0 2 2 1 0 RING-type zinc-finger zf-ribbon_3 PF13248.6 RLN47803.1 - 1.8 8.1 7.4 12 5.4 0.7 3.2 3 0 0 3 3 3 0 zinc-ribbon domain DUF2477 PF10631.9 RLN47803.1 - 3 8.5 12.1 0.16 12.7 1.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2477) Zn-ribbon_8 PF09723.10 RLN47803.1 - 3.2 7.9 5.8 0.45 10.7 0.7 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-ANAPC11 PF12861.7 RLN47803.1 - 5.1 7.2 8.1 0.98 9.5 0.6 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger DOT1 PF08123.13 RLN47804.1 - 6.3e-13 48.7 0.0 9e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 RLN47804.1 - 0.0024 17.7 0.0 0.0096 15.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 RLN47804.1 - 0.0032 17.2 0.0 0.013 15.2 0.0 1.9 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_30 PF05430.11 RLN47804.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.12 RLN47804.1 - 0.031 14.9 0.1 0.23 12.1 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 RLN47804.1 - 0.17 12.6 0.1 1.3 9.8 0.1 2.5 2 1 0 2 2 2 0 Methyltransferase domain Pkinase_Tyr PF07714.17 RLN47805.1 - 1e-43 149.5 0.0 1.3e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN47805.1 - 1.1e-40 139.6 0.0 1.5e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 RLN47805.1 - 1.7e-05 24.9 3.9 3.6e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN47805.1 - 2.2e-05 23.4 0.1 6.4e-05 21.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 RLN47805.1 - 0.04 13.3 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN47805.1 - 0.052 12.9 0.1 0.12 11.7 0.1 1.7 1 1 0 1 1 1 0 Kinase-like RIO1 PF01163.22 RLN47805.1 - 0.066 12.8 0.2 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 RIO1 family ABC2_membrane PF01061.24 RLN47815.1 - 2.7e-28 98.8 32.1 4.2e-28 98.2 32.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN47815.1 - 0.00014 21.7 0.3 0.00014 21.7 0.3 2.6 3 0 0 3 3 3 1 CDR ABC transporter ABC2_membrane PF01061.24 RLN47816.1 - 1.7e-39 135.4 27.7 1.7e-39 135.4 27.7 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RLN47816.1 - 1.2e-18 67.9 1.0 3.7e-15 56.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 RLN47816.1 - 0.0012 18.1 22.0 0.0012 18.1 22.0 2.4 3 0 0 3 3 3 1 ABC-2 family transporter protein AAA_16 PF13191.6 RLN47816.1 - 0.0016 18.8 0.3 0.0096 16.3 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain PDR_assoc PF08370.11 RLN47816.1 - 0.002 17.8 0.2 0.002 17.8 0.2 2.7 3 0 0 3 3 1 1 Plant PDR ABC transporter associated RsgA_GTPase PF03193.16 RLN47816.1 - 0.0037 17.2 0.2 0.18 11.7 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 RLN47816.1 - 0.0076 16.5 0.2 0.05 13.9 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 RLN47816.1 - 0.038 13.6 0.2 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 RLN47816.1 - 0.043 13.3 0.0 4.3 6.7 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RLN47816.1 - 0.047 13.4 3.5 0.24 11.1 0.3 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 RLN47816.1 - 0.051 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.19 RLN47816.1 - 0.083 12.5 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain VirE PF05272.11 RLN47816.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E AAA_21 PF13304.6 RLN47816.1 - 0.18 11.6 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RLN47816.1 - 0.23 11.9 0.1 0.56 10.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain CH_2 PF06294.11 RLN47825.1 - 3.2e-32 110.5 0.4 2.4e-31 107.7 0.0 2.2 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 RLN47825.1 - 9.1e-14 51.1 0.1 3.6e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 CAMSAP CH domain DUF641 PF04859.12 RLN47825.1 - 0.022 15.1 0.8 0.047 14.0 0.8 1.6 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Orn_Arg_deC_N PF02784.16 RLN47826.1 - 6.2e-35 120.7 0.0 1.2e-34 119.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 RLN47826.1 - 2.3e-07 31.0 0.0 5.4e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DUF4140 PF13600.6 RLN47826.1 - 0.15 12.5 1.3 1.2 9.6 0.4 2.9 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DHHC PF01529.20 RLN47827.1 - 1.3e-21 77.1 9.0 1.7e-21 76.7 9.0 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF3675 PF12428.8 RLN47827.1 - 1.3 9.6 4.3 2.3 8.8 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) bVLRF1 PF18826.1 RLN47828.1 - 1.8e-51 173.9 0.0 3.7e-51 172.9 0.0 1.6 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor VATC PF18716.1 RLN47828.1 - 1.4e-10 40.9 0.9 3.6e-10 39.5 0.9 1.7 1 0 0 1 1 1 1 Vms1-associating treble clef domain Ank_4 PF13637.6 RLN47828.1 - 1.6e-07 31.7 0.0 3.2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN47828.1 - 0.0005 20.3 0.1 0.001 19.4 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN47828.1 - 0.0016 19.0 0.1 0.0032 18.0 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 RLN47828.1 - 0.002 18.5 0.4 0.0066 16.8 0.4 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 RLN47828.1 - 0.0022 18.3 0.0 0.0061 17.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat acVLRF1 PF18859.1 RLN47828.1 - 0.04 14.2 0.0 0.04 14.2 0.0 2.5 3 0 0 3 3 2 0 Actinobacteria/chloroflexi VLRF1 release factor CD52 PF15116.6 RLN47828.1 - 0.087 12.9 0.1 0.087 12.9 0.1 2.1 2 0 0 2 2 1 0 CAMPATH-1 antigen Presenilin PF01080.17 RLN47828.1 - 0.42 9.3 0.9 0.73 8.5 0.9 1.4 1 0 0 1 1 1 0 Presenilin Radial_spoke_3 PF06098.11 RLN47828.1 - 0.97 8.7 11.2 1.8 7.7 11.2 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 eIF3_subunit PF08597.10 RLN47828.1 - 3.5 7.5 22.0 2.7 7.8 0.5 2.4 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Eapp_C PF10238.9 RLN47828.1 - 4.9 7.2 11.6 0.45 10.6 4.8 2.7 4 0 0 4 4 4 0 E2F-associated phosphoprotein Pox_Ag35 PF03286.14 RLN47828.1 - 5.2 6.8 12.9 6.5 6.5 7.3 2.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Connexin PF00029.19 RLN47828.1 - 5.2 6.8 4.6 11 5.7 4.6 1.4 1 0 0 1 1 1 0 Connexin Peptidase_S49_N PF08496.10 RLN47828.1 - 5.9 6.9 8.3 21 5.2 8.3 1.9 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Arm PF00514.23 RLN47830.1 - 0.053 13.6 0.9 4.9 7.3 0.4 3.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Zip PF02535.22 RLN47831.1 - 9.7e-17 61.2 6.9 1.2e-16 60.9 6.9 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter LEP503 PF15221.6 RLN47831.1 - 0.0012 19.1 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 Lens epithelial cell protein LEP503 Ephrin_rec_like PF07699.13 RLN47833.1 - 4.1e-06 26.5 0.3 4.1e-06 26.5 0.3 6.2 6 2 1 7 7 7 2 Putative ephrin-receptor like TIG PF01833.24 RLN47833.1 - 6.3e-06 26.2 1.5 6.3e-06 26.2 1.5 2.6 3 0 0 3 3 3 1 IPT/TIG domain TIG_plexin PF17960.1 RLN47833.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 TIG domain RTC PF01137.21 RLN47834.1 - 6.8e-60 202.0 0.0 7.8e-60 201.8 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 RLN47834.1 - 7.3e-35 119.6 0.0 2.1e-34 118.1 0.0 1.8 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain eIF-3_zeta PF05091.12 RLN47835.1 - 4.1e-18 65.7 0.1 5.7e-13 48.7 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SH2_2 PF14633.6 RLN47836.1 - 1.2e-57 194.8 0.0 4.4e-57 193.0 0.0 2.0 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.6 RLN47836.1 - 5.6e-21 74.9 0.4 5.6e-21 74.9 0.4 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif HTH_44 PF14641.6 RLN47836.1 - 5.5e-12 46.1 0.1 1.4e-11 44.8 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 YqgF PF14639.6 RLN47836.1 - 1.2e-09 38.2 0.0 2.6e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 RLN47836.1 - 5.6e-07 30.1 33.0 5.6e-07 30.1 33.0 4.4 2 1 1 4 4 4 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 RLN47836.1 - 5.6e-07 30.4 1.4 3.2e-06 28.0 0.0 3.1 2 1 1 3 3 2 1 HHH domain Tex_YqgF PF16921.5 RLN47836.1 - 1.4e-06 28.8 0.0 9.4e-06 26.1 0.0 2.4 2 0 0 2 2 2 1 Tex protein YqgF-like domain Tex_N PF09371.10 RLN47836.1 - 3.8e-05 23.4 0.0 0.00053 19.7 0.0 2.3 2 0 0 2 2 2 1 Tex-like protein N-terminal domain SH2 PF00017.24 RLN47836.1 - 4.5e-05 23.5 0.0 0.0002 21.4 0.0 2.2 2 0 0 2 2 2 1 SH2 domain HHH_3 PF12836.7 RLN47836.1 - 0.0038 17.5 0.0 0.0079 16.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Flag1_repress PF03614.13 RLN47836.1 - 0.062 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Repressor of phase-1 flagellin LCD1 PF09798.9 RLN47836.1 - 0.63 8.5 9.1 0.046 12.2 1.3 2.2 2 0 0 2 2 2 0 DNA damage checkpoint protein TIG PF01833.24 RLN47837.1 - 1.6e-11 44.1 0.1 7e-11 42.1 0.1 2.2 1 0 0 1 1 1 1 IPT/TIG domain STAS PF01740.21 RLN47837.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 STAS domain Homoserine_dh PF00742.19 RLN47839.1 - 1.1e-53 181.7 0.7 2.1e-53 180.8 0.7 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 RLN47839.1 - 1.2e-11 45.2 0.1 2.6e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain LRR_8 PF13855.6 RLN47840.1 - 0.00047 19.9 0.2 0.0011 18.7 0.2 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 RLN47840.1 - 0.33 11.4 1.2 1.3 9.5 0.5 2.3 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) 2OG-FeII_Oxy_2 PF13532.6 RLN47842.1 - 8.4e-15 55.5 0.0 1.6e-13 51.3 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 RLN47842.1 - 0.00037 20.9 0.0 0.00075 19.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FKBP_C PF00254.28 RLN47843.1 - 3e-34 117.2 0.0 3.3e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase AAA_9 PF12781.7 RLN47861.1 - 1.9e-88 295.3 1.9 4.9e-88 293.9 1.9 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region MT PF12777.7 RLN47861.1 - 1.3e-55 188.8 8.0 2.3e-55 188.0 8.0 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.7 RLN47861.1 - 2.4e-15 56.6 0.0 3.9e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Spc7 PF08317.11 RLN47861.1 - 0.00042 19.3 7.2 0.00042 19.3 7.2 3.4 4 0 0 4 4 4 2 Spc7 kinetochore protein ATG16 PF08614.11 RLN47861.1 - 0.0016 18.7 0.2 0.0016 18.7 0.2 3.4 3 1 1 4 4 4 1 Autophagy protein 16 (ATG16) Viral_DNA_Zn_bi PF03728.13 RLN47861.1 - 0.026 15.1 0.3 0.11 13.0 0.1 2.2 2 0 0 2 2 2 0 Viral DNA-binding protein, zinc binding domain SurA_N_3 PF13624.6 RLN47861.1 - 5.2 6.8 11.0 0.13 12.0 3.0 2.2 2 0 0 2 2 2 0 SurA N-terminal domain G-patch PF01585.23 RLN47862.1 - 4.2e-11 42.6 1.9 4.2e-11 42.6 1.9 2.0 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 RLN47862.1 - 3.5e-06 27.0 0.8 3.5e-06 27.0 0.8 3.0 3 1 0 3 3 3 1 G-patch domain GOLD_2 PF13897.6 RLN47862.1 - 1.8 9.0 9.8 0.55 10.7 0.2 2.4 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking DUF4604 PF15377.6 RLN47862.1 - 3.2 8.2 36.6 3 8.3 14.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) HSP70 PF00012.20 RLN47864.1 - 1.8e-129 432.7 0.0 1.4e-98 330.6 0.0 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 RLN47864.1 - 9e-12 44.4 0.6 2.9e-10 39.5 0.0 2.8 2 1 1 3 3 3 1 MreB/Mbl protein DUF4417 PF14386.6 RLN47865.1 - 0.059 12.9 0.0 0.074 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4417) Rft-1 PF04506.13 RLN47866.1 - 1.8e-106 356.9 11.1 2.3e-106 356.6 11.1 1.0 1 0 0 1 1 1 1 Rft protein MatE PF01554.18 RLN47866.1 - 0.0051 16.5 1.5 0.0051 16.5 1.5 3.3 3 1 1 4 4 4 1 MatE LMWPc PF01451.21 RLN47868.1 - 1.4e-19 70.9 0.1 2e-19 70.4 0.1 1.2 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase NikR_C PF08753.11 RLN47868.1 - 0.14 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 NikR C terminal nickel binding domain Neurensin PF14927.6 RLN47876.1 - 0.012 15.3 0.3 0.044 13.5 0.3 2.0 1 0 0 1 1 1 0 Neurensin Adaptin_N PF01602.20 RLN47876.1 - 0.022 13.4 0.0 0.035 12.7 0.0 1.2 1 0 0 1 1 1 0 Adaptin N terminal region Peptidase_C48 PF02902.19 RLN47877.1 - 0.00011 22.2 0.1 0.00013 21.9 0.1 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C5 PF00770.18 RLN47877.1 - 0.00041 20.1 0.4 0.0013 18.4 0.4 1.8 1 1 0 1 1 1 1 Adenovirus endoprotease COesterase PF00135.28 RLN47880.1 - 8.3e-21 74.4 0.0 1.3e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family fn3 PF00041.21 RLN47881.1 - 8.2e-107 349.8 73.6 9.5e-09 35.5 0.0 33.5 36 0 0 36 36 36 18 Fibronectin type III domain PA14 PF07691.12 RLN47881.1 - 2e-70 235.3 0.5 1.3e-22 80.2 0.0 5.3 5 0 0 5 5 5 3 PA14 domain Filamin PF00630.19 RLN47881.1 - 7.5e-36 123.1 0.0 1.1e-06 29.5 0.1 10.5 11 1 0 11 11 11 5 Filamin/ABP280 repeat Pur_ac_phosph_N PF16656.5 RLN47881.1 - 1.3e-15 57.7 24.9 0.053 14.1 0.1 14.8 15 0 0 15 15 15 4 Purple acid Phosphatase, N-terminal domain GLEYA PF10528.9 RLN47881.1 - 1.1e-09 38.6 1.4 0.03 14.7 0.0 6.2 5 0 0 5 5 5 2 GLEYA domain POTRA_1 PF08478.10 RLN47881.1 - 1.7e-06 28.3 1.4 18 5.7 0.0 8.7 8 0 0 8 8 8 1 POTRA domain, FtsQ-type DUF2369 PF10179.9 RLN47881.1 - 0.0015 18.9 3.6 15 6.0 0.0 6.9 8 0 0 8 8 8 1 Uncharacterised conserved protein (DUF2369) fn3_2 PF16893.5 RLN47881.1 - 0.15 12.2 0.2 2.3 8.4 0.0 3.3 2 0 0 2 2 2 0 Fibronectin type III domain HMA PF00403.26 RLN47881.1 - 0.47 10.9 5.0 35 5.0 0.0 6.2 7 0 0 7 7 7 0 Heavy-metal-associated domain SusE PF14292.6 RLN47881.1 - 1.1 9.5 28.9 1.9 8.8 0.3 9.2 10 0 0 10 10 10 0 SusE outer membrane protein DUF1664 PF07889.12 RLN47899.1 - 0.01 15.8 3.5 0.01 15.8 3.5 7.2 9 0 0 9 9 9 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 RLN47899.1 - 2.9 7.7 20.2 0.017 15.0 3.5 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF724) Baculo_F PF12259.8 RLN47899.1 - 5.5 5.4 9.2 0.22 10.0 1.4 2.1 2 0 0 2 2 2 0 Baculovirus F protein CENP-O PF09496.10 RLN47899.1 - 6.9 6.6 8.6 12 5.8 5.8 2.7 2 1 1 3 3 3 0 Cenp-O kinetochore centromere component FYVE PF01363.21 RLN47900.1 - 2.4e-07 30.8 13.0 7.3e-07 29.2 13.0 1.8 1 1 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN47900.1 - 0.00075 19.7 6.6 0.0019 18.4 6.6 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger zf-RING_UBOX PF13445.6 RLN47900.1 - 0.79 9.8 5.4 14 5.8 2.9 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 RLN47900.1 - 0.93 9.9 9.9 2.8 8.3 10.0 1.9 1 1 1 2 2 2 0 Ring finger domain Ceramidase_alk PF04734.13 RLN47901.1 - 1.6e-138 462.6 0.0 3.8e-137 458.0 0.0 2.0 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 RLN47901.1 - 3.7e-35 121.3 0.9 8.7e-35 120.1 0.1 1.9 2 0 0 2 2 2 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal DUF3883 PF13020.6 RLN47902.1 - 1e-18 67.1 0.1 2.5e-18 65.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) HATPase_c_3 PF13589.6 RLN47902.1 - 0.0025 17.7 0.0 0.0063 16.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1887 PF09002.11 RLN47902.1 - 0.061 12.0 0.1 0.18 10.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) TetR_C_15 PF17918.1 RLN47902.1 - 5.7 7.7 6.2 4.7 8.0 0.0 4.2 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain PCI PF01399.27 RLN47903.1 - 1e-09 38.8 0.1 2.1e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 PCI domain TPR_1 PF00515.28 RLN47903.1 - 0.092 12.6 0.3 1.9 8.4 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat ACT PF01842.25 RLN47904.1 - 6.1e-08 32.3 0.1 1.7e-07 30.9 0.1 1.8 1 1 0 1 1 1 1 ACT domain 2-Hacid_dh_C PF02826.19 RLN47904.1 - 0.00036 19.9 0.1 0.00099 18.5 0.1 1.8 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aminotran_5 PF00266.19 RLN47904.1 - 0.0006 18.9 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V ACT_7 PF13840.6 RLN47904.1 - 0.027 14.3 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 ACT domain Ank_4 PF13637.6 RLN47906.1 - 3.6e-37 126.3 31.9 5.7e-06 26.8 0.1 10.0 5 2 5 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN47906.1 - 3.7e-34 116.3 33.3 0.00031 21.0 0.1 14.3 2 2 13 15 15 15 12 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN47906.1 - 6.3e-34 116.4 29.4 1.6e-07 31.8 0.1 6.8 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN47906.1 - 2.2e-15 55.2 16.1 2.8 8.8 0.0 13.8 14 1 1 15 15 15 3 Ankyrin repeat DUF5049 PF16468.5 RLN47906.1 - 1.9e-05 24.5 0.1 17 5.4 0.0 7.5 5 3 5 10 10 10 1 Domain of unknown function (DUF5049) DUF1979 PF09322.10 RLN47906.1 - 0.00081 19.3 1.5 4.8 7.2 0.0 5.2 5 0 0 5 5 5 1 Domain of unknown function (DUF1979) Ank PF00023.30 RLN47906.1 - 0.0093 16.4 13.3 46 4.7 0.0 9.2 7 3 2 9 9 9 0 Ankyrin repeat PT-VENN PF04829.13 RLN47909.1 - 0.023 14.8 1.1 0.045 13.8 1.1 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif DUF2570 PF10828.8 RLN47909.1 - 0.52 10.2 3.1 1.1 9.1 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2570) DUF3640 PF12342.8 RLN47914.1 - 0.02 14.7 0.1 0.045 13.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3640) GH131_N PF18271.1 RLN47914.1 - 0.037 13.7 0.0 0.041 13.6 0.0 1.0 1 0 0 1 1 1 0 Glycoside hydrolase 131 catalytic N-terminal domain TrbC PF04956.13 RLN47914.1 - 0.13 12.5 0.1 0.16 12.2 0.1 1.2 1 0 0 1 1 1 0 TrbC/VIRB2 family GH131_N PF18271.1 RLN47915.1 - 3.8e-49 167.7 0.1 4.6e-49 167.4 0.1 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain FYVE PF01363.21 RLN47916.1 - 4.4e-13 49.2 4.4 1e-12 48.0 4.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger Sirohm_synth_M PF14824.6 RLN47916.1 - 0.021 14.3 0.3 0.06 12.8 0.3 1.9 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central FYVE_2 PF02318.16 RLN47916.1 - 4.8 7.4 7.9 0.17 12.1 1.2 1.9 3 0 0 3 3 3 0 FYVE-type zinc finger AMP-binding PF00501.28 RLN47917.1 - 6.6e-74 249.0 0.0 9.5e-74 248.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 RLN47917.1 - 2.1e-11 44.0 0.1 3e-10 40.3 0.2 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site zf-BED PF02892.15 RLN47918.1 - 0.03 14.4 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 BED zinc finger Troponin-I_N PF11636.8 RLN47918.1 - 0.13 12.3 1.6 0.37 10.8 1.6 1.8 1 0 0 1 1 1 0 Troponin I residues 1-32 Herpes_UL6 PF01763.16 RLN47918.1 - 0.38 9.2 4.5 0.5 8.8 4.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like Nuc_sug_transp PF04142.15 RLN47919.1 - 7.6e-09 35.2 2.9 7.6e-09 35.2 2.9 1.6 2 0 0 2 2 2 1 Nucleotide-sugar transporter PUNUT PF16913.5 RLN47919.1 - 0.0014 18.0 2.9 0.0014 18.0 2.9 1.7 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 RLN47919.1 - 0.084 11.8 10.5 0.0061 15.5 4.8 1.8 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like zf-met2 PF12907.7 RLN47920.1 - 2.1e-09 37.3 33.1 0.00041 20.4 2.0 5.0 4 1 1 5 5 5 3 Zinc-binding MafB19-deam PF14437.6 RLN47920.1 - 0.013 15.2 7.6 0.63 9.8 0.7 2.1 1 1 1 2 2 2 0 MafB19-like deaminase zinc_ribbon_4 PF13717.6 RLN47920.1 - 0.024 14.6 1.4 5.8 6.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF2083 PF09856.9 RLN47920.1 - 0.028 14.3 4.7 1.1 9.0 0.5 2.2 1 1 1 2 2 2 0 Predicted transcriptional regulator (DUF2083) zf-BED PF02892.15 RLN47920.1 - 0.03 14.3 5.6 0.73 9.9 0.1 2.8 2 1 0 2 2 2 0 BED zinc finger PPR_3 PF13812.6 RLN47920.1 - 0.054 13.6 0.0 1.5 9.0 0.0 2.4 2 1 0 2 2 2 0 Pentatricopeptide repeat domain zinc_ribbon_5 PF13719.6 RLN47920.1 - 0.083 12.7 2.6 7.5 6.4 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 RLN47920.1 - 0.29 12.1 2.1 47 5.2 0.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Tmem26 PF09772.9 RLN47920.1 - 0.45 9.8 2.5 0.74 9.1 0.1 1.9 1 1 1 2 2 2 0 Transmembrane protein 26 Sin3a_C PF16879.5 RLN47920.1 - 0.48 10.1 10.6 1.4 8.6 2.3 2.1 1 1 1 2 2 2 0 C-terminal domain of Sin3a protein Fer4_16 PF13484.6 RLN47920.1 - 0.94 10.5 11.6 3.6 8.6 1.3 2.3 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Eapp_C PF10238.9 RLN47920.1 - 1.7 8.7 17.6 3.4 7.8 3.5 2.2 1 1 1 2 2 2 0 E2F-associated phosphoprotein Sec62 PF03839.16 RLN47920.1 - 2.9 7.4 8.9 3.9 6.9 8.9 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 PGA2 PF07543.12 RLN47920.1 - 3.1 7.8 12.5 3.7 7.5 1.6 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 MMR_HSR1 PF01926.23 RLN47921.1 - 6e-54 181.0 0.0 2.1e-26 92.2 0.0 2.7 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN47921.1 - 2.1e-31 108.6 0.0 4.1e-18 65.4 0.1 2.4 2 1 0 2 2 2 2 Ferrous iron transport protein B KH_dom-like PF14714.6 RLN47921.1 - 5e-30 103.6 0.1 1.1e-29 102.6 0.1 1.6 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal GTP_EFTU PF00009.27 RLN47921.1 - 4.5e-18 65.5 0.0 7.8e-09 35.3 0.4 4.7 3 1 0 3 3 3 3 Elongation factor Tu GTP binding domain Ras PF00071.22 RLN47921.1 - 2e-13 50.3 0.0 6.6e-07 29.1 0.0 2.7 2 1 0 2 2 2 2 Ras family AIG1 PF04548.16 RLN47921.1 - 4.6e-12 45.7 0.0 6.4e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 AIG1 family Dynamin_N PF00350.23 RLN47921.1 - 7.4e-12 45.6 1.2 0.019 15.0 0.0 4.3 3 1 1 4 4 4 3 Dynamin family Arf PF00025.21 RLN47921.1 - 1.2e-10 41.1 0.1 0.032 13.7 0.1 3.3 3 0 0 3 3 3 3 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RLN47921.1 - 4.3e-10 39.7 0.8 0.0087 16.0 0.0 3.5 3 0 0 3 3 3 3 RsgA GTPase Roc PF08477.13 RLN47921.1 - 1.7e-08 34.7 0.0 0.012 15.8 0.0 3.7 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 RLN47921.1 - 5.5e-07 29.2 0.0 0.0015 18.0 0.0 2.2 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 RLN47921.1 - 3.5e-06 27.3 0.1 0.011 16.0 0.0 3.0 3 1 0 3 3 2 2 AAA domain TniB PF05621.11 RLN47921.1 - 5e-06 26.1 0.0 0.044 13.2 0.0 2.5 2 0 0 2 2 2 2 Bacterial TniB protein MeaB PF03308.16 RLN47921.1 - 6.5e-06 25.3 0.3 0.19 10.7 0.1 4.0 4 0 0 4 4 4 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 RLN47921.1 - 1.3e-05 25.8 0.0 0.28 11.7 0.0 3.0 3 0 0 3 3 3 2 ABC transporter NB-ARC PF00931.22 RLN47921.1 - 0.00018 20.8 0.0 0.1 11.8 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain NTPase_1 PF03266.15 RLN47921.1 - 0.0019 18.1 0.1 0.48 10.3 0.0 2.7 2 0 0 2 2 2 1 NTPase AAA_18 PF13238.6 RLN47921.1 - 0.0022 18.5 0.0 2.8 8.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 RLN47921.1 - 0.0058 16.4 0.0 5.2 6.9 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 RLN47921.1 - 0.007 16.7 0.0 7.4 7.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ATPase_2 PF01637.18 RLN47921.1 - 0.0078 16.1 0.0 4.6 7.1 0.1 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 RLN47921.1 - 0.009 15.7 0.0 2.2 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 RLN47921.1 - 0.027 13.7 0.2 5.5 6.2 0.0 2.6 3 0 0 3 3 2 0 Septin MobB PF03205.14 RLN47921.1 - 0.037 13.9 0.1 7.5 6.5 0.0 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 RLN47921.1 - 0.046 13.8 0.0 7.6 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 RLN47921.1 - 0.058 13.1 0.3 3.1 7.5 0.0 3.3 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Ploopntkinase3 PF18751.1 RLN47921.1 - 0.076 12.9 0.0 11 5.9 0.0 2.7 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 AAA_16 PF13191.6 RLN47921.1 - 0.09 13.2 0.9 14 6.0 0.1 3.2 2 2 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 RLN47921.1 - 0.14 12.4 0.0 10 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain GBP PF02263.19 RLN47921.1 - 0.16 11.2 0.0 4.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain cobW PF02492.19 RLN47921.1 - 2.1 7.9 4.8 39 3.8 0.1 3.3 3 1 1 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain SHE3 PF17078.5 RLN47922.1 - 0.00059 19.6 4.0 0.00059 19.6 4.0 3.6 4 0 0 4 4 4 2 SWI5-dependent HO expression protein 3 NYD-SP28 PF14772.6 RLN47922.1 - 0.015 15.3 4.6 0.015 15.3 4.6 5.5 6 0 0 6 6 6 0 Sperm tail FapA PF03961.13 RLN47922.1 - 0.03 12.9 21.0 0.26 9.9 1.1 3.4 3 1 0 3 3 3 0 Flagellar Assembly Protein A Fez1 PF06818.15 RLN47922.1 - 0.16 12.4 43.0 0.043 14.3 13.3 3.8 4 1 0 4 4 4 0 Fez1 ATG16 PF08614.11 RLN47923.1 - 0.0013 19.1 33.1 0.0013 19.1 33.1 5.1 1 1 4 5 5 5 2 Autophagy protein 16 (ATG16) HIP1_clath_bdg PF16515.5 RLN47923.1 - 0.0018 18.8 13.1 0.0018 18.8 13.1 5.5 2 2 1 5 5 5 2 Clathrin-binding domain of Huntingtin-interacting protein 1 Rsa3 PF14615.6 RLN47923.1 - 0.15 11.6 1.2 2.4 7.8 0.1 2.8 2 0 0 2 2 2 0 Ribosome-assembly protein 3 DUF35_N PF12172.8 RLN47926.1 - 1.1 9.2 6.1 3.7 7.5 6.1 1.9 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) MIP PF00230.20 RLN47927.1 - 1.1e-53 182.2 9.4 1.5e-53 181.8 9.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein Phage_holin_8 PF16931.5 RLN47927.1 - 0.022 14.7 0.0 0.068 13.1 0.0 1.8 1 0 0 1 1 1 0 Putative phage holin PNTB PF02233.16 RLN47927.1 - 0.089 11.7 1.0 0.56 9.1 0.4 2.0 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit DUF4064 PF13273.6 RLN47927.1 - 4.4 7.7 7.3 4.9 7.5 2.6 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) CHAT PF12770.7 RLN47928.1 - 6.4e-10 38.9 1.1 2.8e-09 36.8 1.1 1.9 1 1 0 1 1 1 1 CHAT domain AAA_16 PF13191.6 RLN47928.1 - 4.7e-07 30.3 0.3 1.4e-06 28.8 0.3 1.9 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.16 RLN47928.1 - 0.0052 16.3 0.0 0.017 14.6 0.0 1.8 2 0 0 2 2 2 1 PhoH-like protein NACHT PF05729.12 RLN47928.1 - 0.013 15.4 0.0 0.046 13.6 0.0 1.9 1 1 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 RLN47928.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 RLN47928.1 - 0.14 12.4 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 RLN47928.1 - 0.18 11.8 0.0 0.48 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF4577 PF15145.6 RLN47931.1 - 0.22 11.6 0.1 0.44 10.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) IPP-2 PF04979.14 RLN47931.1 - 1.9 9.2 6.1 0.28 11.9 0.4 2.4 2 0 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) ABC_membrane PF00664.23 RLN47936.1 - 2.8e-53 181.3 0.4 3.8e-53 180.9 0.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF3007 PF11460.8 RLN47936.1 - 0.014 15.6 1.5 0.45 10.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) 12TM_1 PF09847.9 RLN47936.1 - 1.6 7.8 4.9 0.76 8.8 0.2 2.2 3 0 0 3 3 3 0 Membrane protein of 12 TMs SET PF00856.28 RLN47951.1 - 1.3e-14 54.9 1.1 2.2e-13 50.9 0.0 3.2 3 1 0 3 3 3 1 SET domain preSET_CXC PF18264.1 RLN47951.1 - 7e-12 45.6 15.6 7e-12 45.6 15.6 3.5 3 1 0 3 3 3 1 CXC domain EF-hand_6 PF13405.6 RLN47952.1 - 4.5e-19 66.7 5.8 1.1e-05 25.0 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 RLN47952.1 - 9.3e-19 65.5 8.5 5.1e-08 31.9 0.1 3.8 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 RLN47952.1 - 8.7e-13 48.5 10.4 1.7e-08 34.7 4.7 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 RLN47952.1 - 2.3e-09 37.0 6.3 0.00011 21.9 0.1 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 RLN47952.1 - 8.7e-09 34.5 7.6 0.0005 19.4 0.0 3.8 3 0 0 3 3 3 3 EF hand EF-hand_10 PF14788.6 RLN47952.1 - 1.1e-06 28.4 1.9 0.071 13.0 0.3 3.4 3 0 0 3 3 3 2 EF hand RCC1_2 PF13540.6 RLN47952.1 - 0.18 11.6 1.0 1.4 8.8 0.9 2.1 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat FA_desaturase PF00487.24 RLN47953.1 - 1.9e-31 109.9 18.8 3.7e-31 108.9 18.8 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Pkinase PF00069.25 RLN47953.1 - 1.3e-12 47.6 0.0 2.6e-10 40.1 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN47953.1 - 0.00032 20.1 0.0 0.0013 18.1 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase DUF3474 PF11960.8 RLN47953.1 - 0.028 14.6 0.0 0.073 13.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) LRR_12 PF18837.1 RLN47954.1 - 0.0038 16.8 0.8 0.022 14.4 0.1 2.1 2 0 0 2 2 2 1 Leucine-rich repeat PAS_7 PF12860.7 RLN47954.1 - 0.086 13.0 1.0 0.16 12.1 1.0 1.4 1 0 0 1 1 1 0 PAS fold PH PF00169.29 RLN47956.1 - 5.7e-10 39.7 0.4 1.9e-09 38.0 0.2 2.0 2 1 0 2 2 2 1 PH domain PH_8 PF15409.6 RLN47956.1 - 1.1e-05 25.6 0.1 0.00015 21.9 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 RLN47956.1 - 0.0012 19.2 1.6 0.0023 18.3 0.0 2.3 3 0 0 3 3 3 1 Pleckstrin homology domain VWA PF00092.28 RLN47957.1 - 4.1e-05 23.9 0.0 4.6e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RLN47957.1 - 0.00019 22.1 0.0 0.0002 21.9 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain HEM4 PF02602.15 RLN47958.1 - 3.1e-29 102.0 0.2 4.3e-29 101.5 0.2 1.2 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TFIIF_beta PF02270.15 RLN47959.1 - 2.8e-09 37.0 0.1 5.3e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Ilar_coat PF01787.16 RLN47959.1 - 0.056 13.2 0.0 0.07 12.9 0.0 1.1 1 0 0 1 1 1 0 Ilarvirus coat protein SNF2_N PF00176.23 RLN47960.1 - 1.6e-60 204.7 0.4 3.8e-60 203.5 0.2 1.7 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN47960.1 - 7.7e-20 71.3 0.0 2.4e-19 69.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-HC5HC2H_2 PF13832.6 RLN47960.1 - 4.5e-19 68.6 7.5 4.5e-19 68.6 7.5 2.5 1 1 1 2 2 2 1 PHD-zinc-finger like domain Chromo PF00385.24 RLN47960.1 - 3.8e-17 61.9 4.5 1.7e-08 34.2 2.5 3.3 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain zf-HC5HC2H PF13771.6 RLN47960.1 - 5.7e-17 61.8 11.2 9.2e-17 61.1 1.1 2.6 2 0 0 2 2 2 1 PHD-like zinc-binding domain ResIII PF04851.15 RLN47960.1 - 5e-12 46.1 0.0 1.8e-10 41.1 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 RLN47960.1 - 4.2e-07 29.4 0.0 9.1e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 QLQ PF08880.11 RLN47960.1 - 1.1e-05 25.1 1.1 2.2e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 QLQ PHD_2 PF13831.6 RLN47960.1 - 0.00056 19.4 0.9 0.00056 19.4 0.9 2.0 2 0 0 2 2 2 1 PHD-finger PDZ_2 PF13180.6 RLN47960.1 - 0.00091 19.5 0.0 0.027 14.8 0.0 2.6 2 0 0 2 2 2 1 PDZ domain DEAD PF00270.29 RLN47960.1 - 0.0011 18.7 0.0 0.0031 17.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RLN47960.1 - 0.052 13.8 0.1 0.91 9.8 0.1 2.9 2 1 0 2 2 2 0 AAA domain PHD PF00628.29 RLN47960.1 - 0.056 13.4 22.9 0.037 13.9 9.8 2.6 2 0 0 2 2 2 0 PHD-finger C1_2 PF03107.16 RLN47960.1 - 4.8 7.6 12.8 0.15 12.4 1.4 2.4 2 0 0 2 2 2 0 C1 domain EF-hand_1 PF00036.32 RLN47961.1 - 5e-11 41.3 1.2 4.6e-05 22.7 0.3 2.6 2 0 0 2 2 2 2 EF hand MIP-T3 PF10243.9 RLN47961.1 - 9.6e-11 41.7 0.0 2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain EF-hand_6 PF13405.6 RLN47961.1 - 1.2e-10 40.4 0.3 0.00041 20.0 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 RLN47961.1 - 2.3e-09 37.6 0.3 6.6e-09 36.1 0.3 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN47961.1 - 7.8e-08 31.5 2.5 0.0054 16.2 0.9 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RLN47961.1 - 2.5e-07 30.4 0.2 1.1e-05 25.2 0.5 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.6 RLN47961.1 - 0.0069 16.7 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain NDK PF00334.19 RLN47963.1 - 3.4e-49 166.3 0.0 3.8e-38 130.6 0.0 3.3 3 0 0 3 3 3 2 Nucleoside diphosphate kinase Katanin_con80 PF13925.6 RLN47963.1 - 0.057 13.5 0.0 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 con80 domain of Katanin ADK PF00406.22 RLN47963.1 - 0.088 12.9 0.0 44 4.1 0.0 3.4 3 0 0 3 3 3 0 Adenylate kinase VCBS PF13517.6 RLN47965.1 - 0.043 14.4 5.3 3.6 8.3 0.4 2.5 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FliN_N PF16973.5 RLN47965.1 - 0.063 13.1 8.1 0.4 10.6 3.3 2.7 2 0 0 2 2 2 0 Flagellar motor switch protein FliN N-terminal EF-hand_1 PF00036.32 RLN47965.1 - 0.24 11.0 1.0 13 5.6 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 RLN47965.1 - 1 9.0 6.8 7.8 6.2 0.6 2.3 2 0 0 2 2 2 0 EF hand Lung_7-TM_R PF06814.13 RLN47968.1 - 3.2e-12 46.3 16.4 5.3e-12 45.6 16.4 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor Ribosomal_S15 PF00312.22 RLN47969.1 - 0.13 12.5 0.5 0.31 11.3 0.5 1.6 1 0 0 1 1 1 0 Ribosomal protein S15 FAM184 PF15665.5 RLN47969.1 - 0.25 11.1 6.7 0.29 10.9 4.6 1.8 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B TPR_MLP1_2 PF07926.12 RLN47969.1 - 2.2 8.3 12.0 4.4 7.4 12.0 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1192 PF06698.11 RLN47969.1 - 7.7 6.7 8.6 28 4.9 0.9 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) MYO10_CC PF16735.5 RLN47969.1 - 8.3 6.6 11.4 7.9 6.7 2.6 2.8 2 0 0 2 2 2 0 Unconventional myosin-X coiled coil domain GFO_IDH_MocA PF01408.22 RLN47970.1 - 2.7e-06 28.2 0.0 5.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 RLN47970.1 - 2.1e-05 24.5 0.0 3.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain ZZ PF00569.17 RLN47975.1 - 1.2e-09 37.8 2.3 2.3e-09 36.9 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 RLN47975.1 - 0.013 15.8 5.4 0.025 14.9 5.4 1.4 1 0 0 1 1 1 0 C1 domain Exo_endo_phos PF03372.23 RLN47976.1 - 1.2e-17 64.2 0.0 1.9e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 RLN47976.1 - 0.057 13.3 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase BTB PF00651.31 RLN47977.1 - 2.2e-05 24.7 0.0 0.058 13.6 0.0 3.3 3 0 0 3 3 3 3 BTB/POZ domain RWP-RK PF02042.15 RLN47978.1 - 2.4e-10 40.2 0.0 4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 RLN47979.1 - 1.3e-09 37.9 0.1 2.3e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_31 PF13560.6 RLN47979.1 - 0.0081 16.5 2.6 0.023 15.0 2.6 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 RLN47979.1 - 0.085 12.7 1.2 0.18 11.6 1.2 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 RLN47979.1 - 0.1 12.7 2.9 0.18 12.0 1.9 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Methyltransf_16 PF10294.9 RLN47988.1 - 9.9e-28 97.0 0.1 2.8e-26 92.3 0.1 2.0 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 RLN47988.1 - 0.0025 17.4 0.0 0.0037 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ceramidase_alk PF04734.13 RLN47990.1 - 4.6e-161 536.9 0.2 9.4e-161 535.9 0.2 1.5 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 RLN47990.1 - 4.6e-41 140.5 0.0 8.1e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Ceramidase_alk PF04734.13 RLN47991.1 - 4.1e-162 540.4 0.2 9.5e-162 539.2 0.2 1.5 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 RLN47991.1 - 2.4e-41 141.4 0.1 4.1e-41 140.7 0.1 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal SMC_N PF02463.19 RLN47992.1 - 6.7e-62 208.8 0.0 1.4e-61 207.8 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 RLN47992.1 - 8.9e-28 97.0 0.0 3e-27 95.2 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 RLN47992.1 - 1.5e-11 44.6 5.0 3.1e-07 30.5 0.0 3.9 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN47992.1 - 1.2e-07 31.4 0.0 2.8e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN47992.1 - 5.4e-06 27.1 31.4 5.4e-06 27.1 31.4 6.1 2 2 0 3 3 3 1 AAA domain ABC_tran PF00005.27 RLN47992.1 - 0.037 14.5 0.0 0.037 14.5 0.0 6.1 5 3 0 6 6 6 0 ABC transporter SbcCD_C PF13558.6 RLN47992.1 - 0.08 13.2 0.0 0.3 11.4 0.0 2.0 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Toprim_Crpt PF13342.6 RLN47992.1 - 0.17 11.9 1.1 0.51 10.3 0.3 2.3 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase DUF5638 PF18688.1 RLN47992.1 - 0.19 12.1 5.3 0.13 12.6 0.7 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5638) HetR_C PF18460.1 RLN47992.1 - 1.8 8.5 5.1 2 8.4 0.3 3.4 2 1 1 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain CABIT PF12736.7 RLN47993.1 - 0.023 14.0 0.0 0.06 12.6 0.0 1.6 2 0 0 2 2 2 0 Cell-cycle sustaining, positive selection, Ank_2 PF12796.7 RLN47995.1 - 1.1e-34 118.9 2.0 5.6e-16 58.9 0.1 5.4 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN47995.1 - 3.9e-29 97.4 9.2 1.1e-06 28.5 0.0 9.2 8 1 1 9 9 9 5 Ankyrin repeat Ank_4 PF13637.6 RLN47995.1 - 6.3e-28 96.8 12.5 3.1e-07 30.8 0.1 7.9 6 2 2 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN47995.1 - 2.3e-27 94.7 10.9 4.3e-08 33.3 0.2 6.5 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 RLN47995.1 - 2.3e-24 84.7 13.5 4.7e-07 30.0 0.0 7.9 7 0 0 7 7 7 4 Ankyrin repeat TPR_12 PF13424.6 RLN47996.1 - 1.3e-14 54.2 9.5 1.8e-09 37.8 1.5 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN47996.1 - 5.4e-13 48.3 5.8 4.3e-06 26.4 0.7 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN47996.1 - 1.1e-12 47.1 6.0 2.4e-05 23.9 0.3 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN47996.1 - 6.8e-12 44.6 6.5 0.00014 21.7 0.2 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN47996.1 - 1.2e-07 31.3 6.0 0.0015 18.4 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN47996.1 - 2.2e-07 30.5 1.6 0.0046 17.1 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat AlgF PF11182.8 RLN47996.1 - 0.0033 17.2 0.0 0.0057 16.5 0.0 1.3 1 0 0 1 1 1 1 Alginate O-acetyl transferase AlgF DUF5113 PF17140.4 RLN47996.1 - 0.007 16.2 0.6 20 5.0 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5113) TPR_MalT PF17874.1 RLN47996.1 - 0.0085 15.5 1.6 0.0085 15.5 1.6 2.0 1 1 1 2 2 2 1 MalT-like TPR region TPR_19 PF14559.6 RLN47996.1 - 0.026 15.0 4.5 0.31 11.6 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 RLN47996.1 - 0.035 13.8 0.3 17 5.2 0.0 3.8 4 1 0 4 4 4 0 TPR repeat TPR_14 PF13428.6 RLN47996.1 - 0.039 14.8 5.1 36 5.5 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 RLN47996.1 - 0.056 12.7 1.8 0.75 9.0 0.2 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN47996.1 - 0.13 12.9 0.9 8.3 7.1 0.2 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 RLN47996.1 - 0.35 11.3 4.8 0.91 10.1 0.1 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN47996.1 - 0.45 10.8 4.8 4.9 7.4 0.7 3.4 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 RLN47996.1 - 5 8.0 4.9 32 5.4 0.1 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat Mon1 PF03164.14 RLN47997.1 - 1.8e-34 119.5 0.0 2.3e-23 83.0 0.0 2.2 2 0 0 2 2 2 2 Trafficking protein Mon1 Glycos_transf_1 PF00534.20 RLN47997.1 - 3.8e-23 81.9 0.0 6.3e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RLN47997.1 - 3.1e-18 66.5 0.0 7.2e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 RLN47997.1 - 6.7e-06 26.4 0.0 2.8e-05 24.4 0.0 2.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Cytochrom_D1 PF02239.16 RLN47997.1 - 0.085 11.4 0.0 0.15 10.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain GnRH PF00446.17 RLN47998.1 - 0.18 12.3 1.7 0.67 10.5 1.7 2.0 1 0 0 1 1 1 0 Gonadotropin-releasing hormone PAC4 PF16093.5 RLN47999.1 - 5.4e-15 55.3 0.1 1.1e-14 54.3 0.1 1.6 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 WD40 PF00400.32 RLN48003.1 - 2.4e-16 59.8 15.5 0.00069 20.4 0.1 8.2 8 0 0 8 8 8 4 WD domain, G-beta repeat PQQ_3 PF13570.6 RLN48003.1 - 0.21 12.1 4.5 41 4.8 0.0 4.4 4 0 0 4 4 4 0 PQQ-like domain WD40 PF00400.32 RLN48004.1 - 4e-51 169.9 15.3 3.7e-07 30.7 0.1 11.4 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN48004.1 - 2.6e-18 66.1 0.6 0.0042 17.4 0.0 7.2 4 3 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RLN48004.1 - 1.6e-08 34.6 0.1 0.09 12.6 0.0 4.3 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 RLN48004.1 - 6e-05 22.2 0.0 1.1 8.2 0.0 3.8 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 RLN48004.1 - 0.00024 20.5 0.0 0.037 13.3 0.0 2.4 2 0 0 2 2 2 2 WD40-like domain Nbas_N PF15492.6 RLN48004.1 - 0.0012 18.2 0.2 0.47 9.7 0.0 3.5 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 RLN48004.1 - 0.0034 17.3 3.0 7.3 6.7 0.0 4.6 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Frtz PF11768.8 RLN48004.1 - 0.033 12.5 0.0 11 4.1 0.0 3.0 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz IKI3 PF04762.12 RLN48004.1 - 0.035 12.1 0.2 1.3 7.0 0.0 3.0 1 1 0 2 2 2 0 IKI3 family NHL PF01436.21 RLN48004.1 - 0.14 12.2 0.8 71 3.7 0.0 4.0 3 0 0 3 3 3 0 NHL repeat Eapp_C PF10238.9 RLN48005.1 - 5.4e-43 146.6 1.0 9.9e-43 145.8 1.0 1.5 1 0 0 1 1 1 1 E2F-associated phosphoprotein Pkinase PF00069.25 RLN48006.1 - 7.4e-35 120.6 0.0 3.5e-23 82.3 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN48006.1 - 1.8e-20 73.3 0.0 1.5e-08 34.3 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase FTA2 PF13095.6 RLN48006.1 - 0.0057 16.3 0.0 0.23 11.1 0.0 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RLN48006.1 - 0.019 14.9 1.4 0.087 12.7 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN48006.1 - 0.03 13.7 0.3 0.079 12.3 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN48006.1 - 0.036 13.4 0.0 1.6 8.0 0.0 2.8 3 0 0 3 3 3 0 Kinase-like Nodulin PF02451.15 RLN48006.1 - 0.093 12.2 2.0 0.22 11.0 2.0 1.5 1 0 0 1 1 1 0 Nodulin Pkinase_fungal PF17667.1 RLN48006.1 - 0.13 11.1 0.1 0.42 9.3 0.1 1.8 1 1 0 1 1 1 0 Fungal protein kinase DUF5315 PF17242.2 RLN48006.1 - 2.5 8.0 8.3 1.7 8.5 0.8 3.2 3 0 0 3 3 3 0 Disordered region of unknown function (DUF5315) Rootletin PF15035.6 RLN48007.1 - 0.00051 20.1 6.6 0.00051 20.1 6.6 3.9 1 1 2 3 3 2 1 Ciliary rootlet component, centrosome cohesion TPR_MLP1_2 PF07926.12 RLN48007.1 - 0.0024 18.0 49.2 0.005 16.9 8.2 3.7 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein Filament PF00038.21 RLN48007.1 - 0.011 15.4 33.3 0.035 13.7 13.9 2.8 1 1 1 2 2 2 0 Intermediate filament protein DUF812 PF05667.11 RLN48007.1 - 0.022 13.7 32.6 0.012 14.5 14.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) APG6_N PF17675.1 RLN48007.1 - 0.028 15.0 15.7 0.028 15.0 15.7 4.6 1 1 3 4 4 4 0 Apg6 coiled-coil region Harakiri PF15196.6 RLN48007.1 - 0.045 14.2 0.1 0.14 12.6 0.1 1.9 1 0 0 1 1 1 0 Activator of apoptosis harakiri DUF4878 PF12870.7 RLN48007.1 - 0.28 11.5 1.4 0.67 10.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4878) ADIP PF11559.8 RLN48007.1 - 0.3 11.2 41.3 0.45 10.6 5.7 4.2 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Cep57_CLD PF14073.6 RLN48007.1 - 1.8 8.5 39.6 0.031 14.3 23.5 3.8 1 1 3 4 4 4 0 Centrosome localisation domain of Cep57 ATG16 PF08614.11 RLN48007.1 - 4.6 7.4 51.2 0.18 12.0 20.6 3.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) FapA PF03961.13 RLN48007.1 - 6.3 5.3 19.0 2.8 6.4 7.6 2.4 1 1 0 2 2 2 0 Flagellar Assembly Protein A RasGAP_C PF03836.15 RLN48007.1 - 7.3 6.7 18.1 18 5.4 0.1 3.7 1 1 1 3 3 3 0 RasGAP C-terminus DUF4472 PF14739.6 RLN48007.1 - 9.7 7.0 33.5 2.9 8.7 4.2 4.5 1 1 2 4 4 4 0 Domain of unknown function (DUF4472) SLC35F PF06027.12 RLN48008.1 - 9.5e-09 35.2 1.4 1.8e-08 34.2 1.4 1.4 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 RLN48008.1 - 1.4e-08 35.0 4.4 1.4e-08 35.0 4.4 3.3 2 1 0 2 2 2 1 EamA-like transporter family PUNUT PF16913.5 RLN48008.1 - 1.1e-06 28.2 0.7 2.6e-06 26.9 0.7 1.6 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport Nuc_sug_transp PF04142.15 RLN48008.1 - 1.6e-05 24.2 3.5 2.5e-05 23.6 3.5 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 RLN48008.1 - 0.00051 19.3 3.1 0.00082 18.7 3.1 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 RLN48008.1 - 0.00095 18.6 6.0 0.0017 17.7 6.0 1.4 1 0 0 1 1 1 1 Triose-phosphate Transporter family CRT-like PF08627.10 RLN48008.1 - 0.28 10.1 16.0 0.0067 15.4 4.3 2.1 1 1 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like Methyltransf_8 PF05148.15 RLN48010.1 - 1.4e-78 263.7 0.3 1.7e-41 142.5 0.0 2.1 1 1 1 2 2 2 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 RLN48010.1 - 7.7e-07 29.7 0.0 2.4e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN48010.1 - 0.00034 21.3 0.0 0.0096 16.6 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN48010.1 - 0.0032 18.2 0.0 0.02 15.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN48010.1 - 0.021 14.2 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 RLN48010.1 - 0.076 12.9 0.0 2.1 8.2 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain Adap_comp_sub PF00928.21 RLN48012.1 - 1.3e-54 185.3 0.0 1.7e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 RLN48012.1 - 3.6e-05 23.7 0.7 5.6e-05 23.1 0.7 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.6 RLN48012.1 - 0.2 11.7 0.5 0.5 10.4 0.5 1.7 1 1 0 1 1 1 0 Regulated-SNARE-like domain PALP PF00291.25 RLN48013.1 - 2.8e-47 161.6 3.2 3.7e-47 161.2 3.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Adap_comp_sub PF00928.21 RLN48015.1 - 2e-21 76.6 0.0 2.2e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Glyco_hydro_2_C PF02836.17 RLN48015.1 - 0.083 12.0 0.0 0.084 12.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DUF5539 PF17693.1 RLN48016.1 - 0.026 14.2 1.0 0.064 12.9 1.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5539) Pkinase_Tyr PF07714.17 RLN48017.1 - 3.1e-40 138.1 0.0 4.4e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN48017.1 - 8.8e-40 136.7 0.0 1.4e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ABC2_membrane_2 PF12679.7 RLN48017.1 - 0.087 12.1 8.7 0.11 11.8 7.6 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein SR-25 PF10500.9 RLN48017.1 - 0.47 10.0 11.3 0.8 9.3 11.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PIG-P PF08510.12 RLN48018.1 - 0.0096 15.8 0.4 0.0096 15.8 0.4 3.3 3 1 0 3 3 3 1 PIG-P PH PF00169.29 RLN48019.1 - 8.5e-18 64.8 0.2 1.9e-07 31.5 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 RLN48019.1 - 6.8e-09 36.1 4.3 0.0034 17.8 0.5 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_12 PF16457.5 RLN48019.1 - 0.00015 22.3 1.4 0.25 11.9 0.1 2.9 2 1 0 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.6 RLN48019.1 - 0.00067 19.9 0.6 3.7 7.9 0.0 3.2 3 0 0 3 3 3 2 Pleckstrin homology domain PH_13 PF16652.5 RLN48019.1 - 0.00084 19.2 1.1 0.14 12.0 0.2 2.2 2 0 0 2 2 2 2 Pleckstrin homology domain PH_17 PF18012.1 RLN48019.1 - 0.01 15.5 0.3 0.039 13.7 0.1 2.0 2 0 0 2 2 2 0 PH domain PH_4 PF15404.6 RLN48019.1 - 0.028 14.2 0.4 0.9 9.3 0.1 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain PH_9 PF15410.6 RLN48019.1 - 0.042 14.2 0.5 3.1 8.2 0.0 2.6 2 1 1 3 3 3 0 Pleckstrin homology domain PH_5 PF15405.6 RLN48019.1 - 0.16 12.1 0.1 11 6.1 0.0 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain DUF2849 PF11011.8 RLN48019.1 - 0.27 11.9 1.8 2.5 8.9 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2849) mRNA_cap_C PF03919.15 RLN48021.1 - 0.0073 16.9 0.0 0.014 16.0 0.0 1.5 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain GP120 PF00516.18 RLN48021.1 - 0.099 11.2 0.1 0.11 11.1 0.1 1.0 1 0 0 1 1 1 0 Envelope glycoprotein GP120 bZIP_1 PF00170.21 RLN48022.1 - 3.2e-09 36.7 17.4 3.2e-09 36.7 17.4 4.0 3 1 1 4 4 4 1 bZIP transcription factor bZIP_2 PF07716.15 RLN48022.1 - 1.1e-06 28.6 12.5 1.1e-06 28.6 12.5 3.3 3 1 0 3 3 3 1 Basic region leucine zipper Sigma70_r3 PF04539.16 RLN48022.1 - 0.011 15.8 0.6 0.2 11.8 0.0 2.9 3 0 0 3 3 3 0 Sigma-70 region 3 HTH_20 PF12840.7 RLN48022.1 - 0.038 14.0 0.0 0.22 11.6 0.0 2.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2981 PF11200.8 RLN48022.1 - 0.14 11.9 0.8 0.29 10.9 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) YabA PF06156.13 RLN48022.1 - 0.35 11.5 17.6 0.92 10.2 1.3 3.2 2 1 1 3 3 3 0 Initiation control protein YabA LTXXQ PF07813.12 RLN48022.1 - 8.4 7.2 14.3 8.4 7.2 0.1 4.2 4 1 0 4 4 4 0 LTXXQ motif family protein Pectate_lyase PF03211.13 RLN48037.1 - 7.5e-78 260.7 5.4 7.5e-78 260.7 5.4 1.6 2 0 0 2 2 2 1 Pectate lyase PAP1 PF08601.10 RLN48037.1 - 0.13 11.9 17.4 0.21 11.3 17.4 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Dermcidin PF15291.6 RLN48038.1 - 0.63 10.6 5.6 4.3 8.0 1.2 2.3 1 1 1 2 2 2 0 Dermcidin, antibiotic peptide Abhydrolase_6 PF12697.7 RLN48040.1 - 1e-05 26.2 0.0 0.00026 21.7 0.0 2.0 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 RLN48041.1 - 5.9e-11 43.4 2.1 7.3e-11 43.1 2.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN48041.1 - 8.9e-06 25.1 0.0 2.4e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 RCC1 PF00415.18 RLN48043.1 - 6.1e-33 113.2 14.7 5e-11 43.1 0.8 5.1 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN48043.1 - 2.4e-24 84.6 17.9 7.1e-09 35.2 1.8 4.3 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat Exo_endo_phos PF03372.23 RLN48044.1 - 0.00041 19.9 0.0 0.0013 18.3 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pectinesterase PF01095.19 RLN48044.1 - 0.13 11.0 0.0 0.27 9.9 0.0 1.4 1 0 0 1 1 1 0 Pectinesterase PDZ PF00595.24 RLN48045.1 - 7.9e-07 29.3 0.0 0.003 17.9 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 RLN48045.1 - 2.9e-06 27.0 0.1 0.014 15.2 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 RLN48045.1 - 0.00016 21.9 0.1 0.17 12.3 0.0 2.5 2 0 0 2 2 2 2 PDZ domain Ribosomal_60s PF00428.19 RLN48045.1 - 1 10.0 9.0 0.15 12.7 4.3 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Asp PF00026.23 RLN48046.1 - 1.6e-20 73.8 0.2 2.7e-20 73.0 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 RLN48046.1 - 0.018 14.8 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal RTTN_N PF14726.6 RLN48048.1 - 0.64 10.9 7.9 0.12 13.2 0.4 3.6 3 0 0 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning DUF1438 PF07270.11 RLN48049.1 - 0.023 14.8 0.1 0.049 13.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1438) SANTA PF09133.10 RLN48049.1 - 0.04 14.4 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 SANTA (SANT Associated) HSD3 PF15244.6 RLN48050.1 - 0.31 10.5 6.1 0.47 9.9 6.1 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 PH PF00169.29 RLN48051.1 - 1.3e-09 38.5 0.0 9.9e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_3 PF14593.6 RLN48051.1 - 1.7e-08 34.5 0.1 0.00015 21.8 0.1 2.5 1 1 1 2 2 2 2 PH domain PDZ_6 PF17820.1 RLN48051.1 - 3.5e-08 33.2 0.2 0.00097 18.9 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 RLN48051.1 - 1.3e-05 25.5 0.1 0.00045 20.5 0.0 2.4 2 0 0 2 2 2 1 PDZ domain PH_8 PF15409.6 RLN48051.1 - 0.018 15.3 1.0 0.51 10.7 0.2 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain PDZ_2 PF13180.6 RLN48051.1 - 0.052 13.9 0.0 3.2 8.1 0.0 2.5 2 0 0 2 2 2 0 PDZ domain GRIN_C PF15235.6 RLN48051.1 - 0.19 12.0 0.0 0.46 10.7 0.0 1.6 1 0 0 1 1 1 0 G protein-regulated inducer of neurite outgrowth C-terminus DUF4498 PF14926.6 RLN48052.1 - 3e-56 190.5 0.0 5.6e-56 189.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) zf-HIT PF04438.16 RLN48052.1 - 2.9e-09 36.6 11.4 2.9e-09 36.6 11.4 1.6 2 0 0 2 2 2 1 HIT zinc finger YL1_C PF08265.11 RLN48052.1 - 0.016 15.0 0.1 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain zf-B_box PF00643.24 RLN48052.1 - 2.1 8.6 6.9 5 7.4 6.9 1.5 1 0 0 1 1 1 0 B-box zinc finger zf-MYND PF01753.18 RLN48052.1 - 7.5 6.7 18.0 1.5 9.0 13.9 1.9 2 0 0 2 2 2 0 MYND finger MULE PF10551.9 RLN48053.1 - 1.3e-06 28.8 0.0 3e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 RLN48053.1 - 0.00016 21.3 0.1 0.00038 20.0 0.1 1.7 1 0 0 1 1 1 1 SWIM zinc finger DBD_Tnp_Mut PF03108.15 RLN48053.1 - 0.0012 18.8 0.1 0.003 17.5 0.1 1.6 1 0 0 1 1 1 1 MuDR family transposase zf-CCHC_4 PF14392.6 RLN48053.1 - 0.18 11.6 0.4 0.42 10.4 0.4 1.7 1 0 0 1 1 1 0 Zinc knuckle AT_hook PF02178.19 RLN48053.1 - 0.42 10.6 4.6 0.13 12.2 0.5 2.3 2 0 0 2 2 2 0 AT hook motif zf-CCHC_2 PF13696.6 RLN48053.1 - 0.54 10.1 1.9 1 9.2 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_L12_N PF16320.5 RLN48053.1 - 6.8 6.5 6.2 1.6 8.5 0.0 2.9 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain Pro_dh PF01619.18 RLN48054.1 - 1.2e-78 264.6 0.0 4.2e-78 262.9 0.0 1.7 1 1 0 1 1 1 1 Proline dehydrogenase EF-hand_7 PF13499.6 RLN48054.1 - 0.01 16.3 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair AP_endonuc_2 PF01261.24 RLN48054.1 - 0.073 12.5 0.2 0.25 10.8 0.2 1.9 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel HGTP_anticodon PF03129.20 RLN48055.1 - 1.8e-20 72.8 0.0 4.5e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 RLN48055.1 - 3.3e-11 43.5 0.0 7.5e-10 39.1 0.0 2.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 RLN48055.1 - 1.6e-07 31.3 3.3 1.6e-07 31.3 3.3 2.1 2 0 0 2 2 2 1 WHEP-TRS domain Seryl_tRNA_N PF02403.22 RLN48055.1 - 2 8.7 4.3 1.3 9.3 0.0 2.6 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Bac_rhamnosid_C PF17390.2 RLN48056.1 - 2.3e-11 43.3 0.2 8.9e-11 41.4 0.0 2.0 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 RLN48056.1 - 3.9e-10 39.5 0.2 8.9e-10 38.3 0.2 1.7 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 RLN48056.1 - 0.023 13.5 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Trehalase adh_short PF00106.25 RLN48057.1 - 2.8e-42 144.4 0.6 4.1e-42 143.9 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN48057.1 - 2.9e-30 105.6 2.1 4.1e-30 105.1 2.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN48057.1 - 7.3e-06 26.0 0.5 1.2e-05 25.3 0.5 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 RLN48057.1 - 0.0041 16.5 0.0 0.0056 16.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 RLN48057.1 - 0.086 12.3 0.1 0.44 10.0 0.1 2.0 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family Myb_DNA-bind_4 PF13837.6 RLN48058.1 - 9.2e-05 22.8 0.1 0.00024 21.4 0.1 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 RLN48059.1 - 0.0007 19.9 0.1 0.0016 18.8 0.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 RLN48059.1 - 0.046 14.7 0.0 0.11 13.4 0.0 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain TH1 PF04858.13 RLN48060.1 - 1.1e-83 281.9 0.0 2.7e-83 280.6 0.0 1.6 1 1 0 1 1 1 1 TH1 protein WW PF00397.26 RLN48060.1 - 4.8e-17 61.7 12.7 1.9e-08 34.3 2.8 2.5 2 0 0 2 2 2 2 WW domain HipN PF18253.1 RLN48060.1 - 0.0012 18.5 0.0 0.0032 17.1 0.0 1.7 1 0 0 1 1 1 1 Hsp70-interacting protein N N-terminal domain CDC27 PF09507.10 RLN48060.1 - 5.6 6.2 34.7 9.5 5.5 34.7 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 KxDL PF10241.9 RLN48066.1 - 0.18 12.1 1.8 2.1 8.7 0.7 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein MPS2 PF17060.5 RLN48066.1 - 0.22 10.7 2.1 0.29 10.3 2.1 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 ProSAAS PF07259.12 RLN48066.1 - 2.4 8.1 10.7 1.3 8.9 2.9 2.2 2 0 0 2 2 2 0 ProSAAS precursor HHH_8 PF14716.6 RLN48071.1 - 1.9e-16 60.2 0.2 5.6e-08 33.0 0.0 3.2 3 0 0 3 3 3 2 Helix-hairpin-helix domain HEAT_PBS PF03130.16 RLN48071.1 - 0.14 12.9 1.0 1.6 9.6 0.1 2.9 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat DUF913 PF06025.12 RLN48071.1 - 0.23 10.4 1.3 0.39 9.7 1.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Senescence_reg PF04520.13 RLN48071.1 - 0.24 12.2 7.6 0.43 11.4 7.6 1.5 1 1 0 1 1 1 0 Senescence regulator Myc_N PF01056.18 RLN48071.1 - 0.41 10.5 6.9 0.11 12.4 1.1 2.0 2 0 0 2 2 2 0 Myc amino-terminal region RNA_pol_3_Rpc31 PF11705.8 RLN48071.1 - 0.57 10.4 14.4 0.22 11.7 7.9 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 eIF-3c_N PF05470.12 RLN48071.1 - 0.77 8.0 4.6 1.3 7.3 4.6 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus NOA36 PF06524.12 RLN48071.1 - 1.1 8.6 10.0 0.15 11.4 3.9 2.0 2 0 0 2 2 2 0 NOA36 protein DUF4820 PF16091.5 RLN48071.1 - 2.5 7.4 4.6 1.5 8.1 2.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF667 PF05018.13 RLN48077.1 - 2.2e-27 96.0 0.0 4.1e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF667) FAR1 PF03101.15 RLN48077.1 - 1.5e-08 35.2 14.6 0.019 15.7 1.0 4.8 4 0 0 4 4 4 3 FAR1 DNA-binding domain Cauli_VI PF01693.16 RLN48077.1 - 0.11 12.8 3.2 0.12 12.7 0.0 2.7 3 0 0 3 3 3 0 Caulimovirus viroplasmin DUF3319 PF11782.8 RLN48077.1 - 0.18 11.8 0.0 4.8 7.2 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3319) PDEase_I PF00233.19 RLN48078.1 - 3.2e-79 266.0 1.6 4.8e-79 265.4 1.6 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ion_trans PF00520.31 RLN48078.1 - 1.2e-09 37.8 9.1 1.9e-09 37.1 9.1 1.3 1 0 0 1 1 1 1 Ion transport protein FYVE PF01363.21 RLN48079.1 - 1.3e-12 47.6 11.4 1.3e-12 47.6 11.4 2.2 2 0 0 2 2 2 1 FYVE zinc finger PSP1 PF04468.12 RLN48079.1 - 2.1e-11 43.9 0.5 6e-11 42.5 0.5 1.8 1 0 0 1 1 1 1 PSP1 C-terminal conserved region FYVE_2 PF02318.16 RLN48079.1 - 0.001 19.2 6.3 0.0042 17.3 6.3 2.1 1 0 0 1 1 1 1 FYVE-type zinc finger Kinesin PF00225.23 RLN48081.1 - 1.6e-96 323.1 0.1 3.8e-96 321.9 0.1 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN48081.1 - 7e-46 155.9 1.1 2.6e-45 154.0 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding adh_short PF00106.25 RLN48081.1 - 2e-19 69.8 1.1 1.2e-09 38.0 0.0 3.0 3 0 0 3 3 3 2 short chain dehydrogenase UPRTase PF14681.6 RLN48081.1 - 1.8e-16 60.2 0.4 9.9e-08 31.7 0.0 3.4 2 1 1 3 3 3 3 Uracil phosphoribosyltransferase adh_short_C2 PF13561.6 RLN48081.1 - 2.2e-15 56.9 0.5 1.4e-09 37.8 0.1 2.8 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Zn-ribbon_8 PF09723.10 RLN48081.1 - 0.068 13.3 1.0 0.36 11.0 1.0 2.3 1 0 0 1 1 1 0 Zinc ribbon domain DUF1664 PF07889.12 RLN48081.1 - 0.098 12.7 19.4 1.7 8.7 0.7 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 RLN48081.1 - 2.6 7.9 20.7 0.29 10.9 0.2 4.0 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Polysacc_deac_1 PF01522.21 RLN48083.1 - 9.3e-12 44.9 0.0 1.6e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Proteasome PF00227.26 RLN48084.1 - 3.2e-36 124.6 0.7 1.5e-32 112.6 0.0 2.0 2 0 0 2 2 2 2 Proteasome subunit DUF3540 PF12059.8 RLN48084.1 - 0.049 13.5 0.4 0.072 12.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) NAGidase PF07555.13 RLN48084.1 - 0.057 12.7 0.1 0.094 12.0 0.1 1.3 1 1 0 1 1 1 0 beta-N-acetylglucosaminidase TRAPPC-Trs85 PF12739.7 RLN48085.1 - 3e-76 257.0 0.0 4.5e-76 256.4 0.0 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.11 RLN48085.1 - 0.057 10.8 0.0 0.13 9.6 0.0 1.5 2 0 0 2 2 2 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit STIL_N PF15253.6 RLN48086.1 - 1e-17 64.2 0.0 1.7e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 SCL-interrupting locus protein N-terminus PI3_PI4_kinase PF00454.27 RLN48088.1 - 9.9e-20 71.4 0.0 1.8e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Atg14 PF10186.9 RLN48089.1 - 4.5e-07 29.3 8.2 2.1e-06 27.1 8.2 1.8 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 APG6 PF04111.12 RLN48089.1 - 0.0015 18.6 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 Apg6 BARA domain C2 PF00168.30 RLN48089.1 - 0.007 16.6 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain Mei5 PF10376.9 RLN48089.1 - 0.12 12.2 1.5 0.24 11.3 1.5 1.5 1 0 0 1 1 1 0 Double-strand recombination repair protein Pkinase PF00069.25 RLN48100.1 - 3.4e-65 220.0 0.0 6e-65 219.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN48100.1 - 1.2e-41 142.7 0.0 3.2e-41 141.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Response_reg PF00072.24 RLN48100.1 - 2.2e-23 82.5 0.3 4.6e-23 81.5 0.3 1.6 1 0 0 1 1 1 1 Response regulator receiver domain DUF547 PF04784.14 RLN48100.1 - 2.8e-21 75.8 0.0 5.2e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Kinase-like PF14531.6 RLN48100.1 - 2.3e-05 23.9 0.0 3.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DEP PF00610.21 RLN48100.1 - 0.025 14.7 0.0 0.31 11.1 0.0 2.4 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Ras PF00071.22 RLN48101.1 - 1.3e-32 112.6 0.0 1.7e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN48101.1 - 1.7e-14 54.1 0.0 1.9e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 RLN48101.1 - 0.011 15.8 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.21 RLN48101.1 - 0.014 14.9 0.0 0.016 14.6 0.0 1.0 1 0 0 1 1 1 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RLN48101.1 - 0.096 12.6 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 RLN48101.1 - 0.16 12.3 0.0 0.2 12.0 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain Op_neuropeptide PF08035.11 RLN48102.1 - 0.043 13.7 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Opioids neuropeptide PPR PF01535.20 RLN48102.1 - 0.19 12.1 0.0 17 5.9 0.0 2.9 3 0 0 3 3 3 0 PPR repeat MA3 PF02847.17 RLN48102.1 - 0.2 11.7 0.3 29 4.7 0.0 3.5 3 1 0 4 4 4 0 MA3 domain ANAPC3 PF12895.7 RLN48102.1 - 2.3 8.5 4.0 37 4.6 0.1 4.0 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 SPRY PF00622.28 RLN48103.1 - 2.6e-24 85.6 0.0 4.7e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Telomere_Sde2_2 PF13297.6 RLN48103.1 - 6e-23 80.3 4.0 6.6e-23 80.1 2.5 1.9 2 0 0 2 2 2 1 Telomere stability C-terminal Sde2_N_Ubi PF13019.6 RLN48103.1 - 4.8e-17 62.3 0.9 4.8e-17 62.3 0.9 2.8 3 0 0 3 3 3 1 Silencing defective 2 N-terminal ubiquitin domain MAT1 PF06391.13 RLN48103.1 - 0.1 12.4 3.6 6.2 6.6 0.2 2.2 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 CPSF100_C PF13299.6 RLN48103.1 - 0.84 9.8 5.3 0.45 10.7 0.5 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal zf-CCCH PF00642.24 RLN48103.1 - 1 9.3 3.2 1.9 8.5 1.3 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MOSC_N PF03476.16 RLN48104.1 - 1.2e-32 112.3 0.0 2.4e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 RLN48104.1 - 7.1e-24 84.3 0.0 1.2e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 MOSC domain Glycos_transf_1 PF00534.20 RLN48109.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Lipase_3 PF01764.25 RLN48113.1 - 2.5e-06 27.4 0.0 7.5e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 RLN48113.1 - 5.9e-05 23.8 0.0 0.00014 22.5 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 RLN48113.1 - 0.0051 16.6 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 RLN48113.1 - 0.02 14.1 0.3 0.1 11.9 0.1 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN48113.1 - 0.05 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.12 RLN48113.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2974 PF11187.8 RLN48113.1 - 0.095 12.2 0.4 1.1 8.8 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2974) Retrotrans_gag PF03732.17 RLN48114.1 - 0.0004 20.6 0.1 0.00073 19.8 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein RAB3GAP2_N PF14655.6 RLN48126.1 - 8.2e-06 25.3 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Annexin PF00191.20 RLN48127.1 - 4.2e-51 170.9 0.3 2.8e-13 49.7 0.0 5.2 5 0 0 5 5 5 5 Annexin DUF515 PF04415.12 RLN48127.1 - 1.5 7.1 16.6 2.3 6.5 15.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF515) Helitron_like_N PF14214.6 RLN48128.1 - 2.7e-11 44.0 0.0 7.3e-11 42.6 0.0 1.7 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus MPP6 PF10175.9 RLN48129.1 - 0.1 13.1 0.1 0.13 12.8 0.1 1.1 1 0 0 1 1 1 0 M-phase phosphoprotein 6 p450 PF00067.22 RLN48131.1 - 5e-36 124.4 0.0 8.8e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 TPR_5 PF12688.7 RLN48131.1 - 0.084 13.1 4.5 3.3 8.0 0.2 2.6 3 0 0 3 3 3 0 Tetratrico peptide repeat WD40 PF00400.32 RLN48132.1 - 7.5e-24 83.6 8.5 0.00035 21.3 0.0 8.6 8 2 1 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN48132.1 - 2.1e-10 40.8 0.1 0.11 12.8 0.0 5.7 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain HPS3_N PF14761.6 RLN48132.1 - 0.15 11.6 0.0 30 4.1 0.0 3.1 3 0 0 3 3 3 0 Hermansky-Pudlak syndrome 3 CPSF_A PF03178.15 RLN48132.1 - 0.15 11.3 0.0 1.3 8.3 0.0 2.5 4 0 0 4 4 4 0 CPSF A subunit region SLBP_RNA_bind PF15247.6 RLN48132.1 - 0.21 11.8 0.3 0.74 10.0 0.3 2.0 1 0 0 1 1 1 0 Histone RNA hairpin-binding protein RNA-binding domain RRM_1 PF00076.22 RLN48133.1 - 7.7e-42 141.0 0.0 3.8e-18 65.1 0.0 4.3 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN48133.1 - 0.001 19.2 0.0 3.3 7.9 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif Dynein_attach_N PF15867.5 RLN48134.1 - 6.7e-21 74.0 2.3 1e-20 73.4 2.3 1.3 1 0 0 1 1 1 1 Dynein attachment factor N-terminus RPAP3_C PF13877.6 RLN48134.1 - 3.5e-07 30.7 0.1 2.1e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 LysE PF01810.18 RLN48135.1 - 0.023 14.2 0.6 0.41 10.1 0.1 2.6 2 1 1 3 3 3 0 LysE type translocator TRM13 PF05206.14 RLN48136.1 - 1.2e-67 228.2 0.0 1.2e-66 224.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 RLN48136.1 - 4.7e-10 39.1 2.7 4.7e-10 39.1 2.7 3.0 3 0 0 3 3 3 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 RLN48136.1 - 1.2e-07 31.5 0.0 2.5e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.6 RLN48136.1 - 0.017 15.1 1.4 0.052 13.5 0.1 2.4 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.17 RLN48136.1 - 0.081 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 RLN48136.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain UPF0029 PF01205.19 RLN48137.1 - 2e-32 111.7 0.0 2.8e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 TFIID-31kDa PF02291.15 RLN48138.1 - 4.6e-22 78.4 0.4 1.7e-08 34.5 0.0 3.1 2 1 1 3 3 3 3 Transcription initiation factor IID, 31kD subunit FH2 PF02181.23 RLN48140.1 - 3.5e-31 108.7 0.1 3.1e-25 89.1 0.1 2.2 2 0 0 2 2 2 2 Formin Homology 2 Domain Ank_2 PF12796.7 RLN48140.1 - 6e-30 103.7 6.7 8e-12 45.6 0.5 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN48140.1 - 8.4e-27 93.2 6.2 4.2e-13 49.5 0.9 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN48140.1 - 1.1e-19 68.4 7.2 0.0004 20.6 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 RLN48140.1 - 3.5e-19 68.3 14.6 0.00012 22.4 0.5 6.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 RLN48140.1 - 2.6e-13 49.9 9.0 2e-05 24.8 0.7 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) C2 PF00168.30 RLN48140.1 - 4.3e-05 23.8 0.0 9.4e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain PH_12 PF16457.5 RLN48140.1 - 4.3e-05 24.1 0.3 0.0003 21.4 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 RLN48140.1 - 0.0007 20.1 0.0 0.002 18.6 0.0 1.8 1 0 0 1 1 1 1 PH domain Mcp5_PH PF12814.7 RLN48140.1 - 0.005 17.0 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH_2 PF08458.10 RLN48140.1 - 0.019 15.3 0.0 0.056 13.8 0.0 1.7 1 0 0 1 1 1 0 Plant pleckstrin homology-like region KIAA1430 PF13879.6 RLN48141.1 - 6.4e-28 97.5 15.2 6.4e-28 97.5 15.2 1.6 2 0 0 2 2 2 1 KIAA1430 homologue TMCO5 PF14992.6 RLN48141.1 - 0.036 13.7 0.6 0.036 13.7 0.6 2.2 1 1 1 2 2 2 0 TMCO5 family Cyt-b5 PF00173.28 RLN48142.1 - 8.1e-12 45.1 0.0 1.7e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BTB PF00651.31 RLN48142.1 - 0.076 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Arginase PF00491.21 RLN48143.1 - 2.7e-63 214.1 0.0 3.4e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Arginase family Ribosomal_L13e PF01294.18 RLN48144.1 - 3.6e-67 225.7 7.7 5.4e-61 205.6 3.5 2.1 2 0 0 2 2 2 2 Ribosomal protein L13e BT1 PF03092.16 RLN48145.1 - 5.4e-26 90.9 14.4 1.5e-14 53.1 0.6 2.0 2 0 0 2 2 2 2 BT1 family Phage_holin_1 PF04531.13 RLN48145.1 - 0.16 12.5 1.0 2.9 8.5 0.1 2.8 2 0 0 2 2 2 0 Bacteriophage holin TRAUB PF08164.12 RLN48146.1 - 7.4e-23 80.9 0.1 7.4e-23 80.9 0.1 2.6 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 RLN48146.1 - 3.4e-14 53.7 0.7 3.4e-14 53.7 0.7 3.2 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor PAC1 PF16094.5 RLN48146.1 - 0.33 10.1 2.8 0.66 9.1 2.8 1.4 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Ank_2 PF12796.7 RLN48147.1 - 2e-30 105.2 3.9 6.8e-12 45.8 0.2 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) CCDC53 PF10152.9 RLN48147.1 - 9.6e-28 97.5 32.1 4.1e-10 40.3 0.2 5.0 4 1 0 4 4 4 3 Subunit CCDC53 of WASH complex Ank_4 PF13637.6 RLN48147.1 - 1.9e-25 88.9 1.4 1e-10 41.9 0.1 5.2 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN48147.1 - 5.1e-24 83.6 6.4 1.8e-05 24.9 0.1 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 RLN48147.1 - 1.4e-22 77.3 3.7 6.3e-05 23.1 0.0 6.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 RLN48147.1 - 1.2e-17 63.7 1.8 1.8e-08 34.5 0.3 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) AF-4 PF05110.13 RLN48147.1 - 0.1 10.7 11.7 0.15 10.1 11.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein HlyD_2 PF12700.7 RLN48147.1 - 0.15 10.8 2.0 0.25 10.0 2.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein zf-MYND PF01753.18 RLN48147.1 - 0.21 11.7 5.2 0.43 10.7 5.2 1.5 1 0 0 1 1 1 0 MYND finger F-box-like PF12937.7 RLN48148.1 - 0.079 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 F-box-like SAC3_GANP PF03399.16 RLN48149.1 - 2.6e-86 289.6 0.1 2.6e-86 289.6 0.1 2.7 3 0 0 3 3 3 1 SAC3/GANP family Mito_carr PF00153.27 RLN48150.1 - 1.1e-68 227.1 4.1 1.2e-24 86.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Elicitin PF00964.17 RLN48211.1 - 2.6e-14 53.1 0.2 2.6e-14 53.1 0.2 2.6 2 1 0 2 2 2 1 Elicitin MID_MedPIWI PF18296.1 RLN48211.1 - 0.35 10.6 8.4 0.41 10.4 8.4 1.2 1 0 0 1 1 1 0 MID domain of medPIWI RIFIN PF02009.16 RLN48211.1 - 1.1 9.1 5.6 1 9.2 5.6 1.1 1 0 0 1 1 1 0 Rifin Plasmodium_Vir PF05795.11 RLN48211.1 - 1.1 8.6 5.2 1 8.7 5.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SWI-SNF_Ssr4 PF08549.10 RLN48211.1 - 2.8 6.4 8.9 3.1 6.3 8.9 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SpoIIIAH PF12685.7 RLN48211.1 - 6.1 6.6 16.2 8.2 6.2 16.2 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein DHC_N2 PF08393.13 RLN48222.1 - 1.1e-65 222.3 0.0 1.1e-65 222.3 0.0 2.8 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 RLN48222.1 - 1.7e-31 109.4 3.0 8.6e-30 103.8 0.5 2.9 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 RLN48222.1 - 5.6e-19 68.5 2.4 1.3e-17 64.0 0.1 3.0 2 1 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_AAA_lid PF17852.1 RLN48222.1 - 2.6e-14 53.4 0.1 4.1e-13 49.5 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_9 PF12781.7 RLN48222.1 - 2.1e-13 49.9 1.0 4.4e-10 39.1 0.0 2.9 2 0 0 2 2 2 2 ATP-binding dynein motor region MT PF12777.7 RLN48222.1 - 6.1e-12 45.2 0.1 1.4e-11 44.0 0.1 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RLN48222.1 - 1.1e-10 41.6 0.3 6.2e-10 39.2 0.0 2.6 3 0 0 3 3 1 1 Dynein heavy chain region D6 P-loop domain AAA_7 PF12775.7 RLN48222.1 - 2.9e-06 26.9 0.1 0.05 13.1 0.0 4.4 4 0 0 4 4 4 1 P-loop containing dynein motor region Dynein_C PF18199.1 RLN48222.1 - 0.00026 20.3 0.3 0.0013 18.0 0.1 2.2 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_lid_1 PF17857.1 RLN48222.1 - 0.00057 20.1 0.0 0.0018 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain TsaE PF02367.17 RLN48222.1 - 0.0042 17.1 1.6 2.9 7.9 0.1 3.5 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 RLN48222.1 - 0.0046 17.5 0.4 0.62 10.6 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RLN48222.1 - 0.0046 17.2 0.5 14 5.9 0.1 4.5 3 1 0 3 3 3 0 AAA domain AAA_30 PF13604.6 RLN48222.1 - 0.015 15.0 1.6 6.1 6.5 0.1 2.9 2 0 0 2 2 2 0 AAA domain PapC_C PF13953.6 RLN48222.1 - 0.015 15.1 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 PapC C-terminal domain ATP-synt_ab PF00006.25 RLN48222.1 - 0.021 14.5 0.5 4.4 6.9 0.1 3.6 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_16 PF13191.6 RLN48222.1 - 0.023 15.1 9.9 1.9 8.8 0.1 5.4 5 0 0 5 5 4 0 AAA ATPase domain AAA_lid_11 PF18198.1 RLN48222.1 - 0.029 14.2 0.0 0.087 12.6 0.0 1.8 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain AAA_14 PF13173.6 RLN48222.1 - 0.05 13.6 0.0 26 4.8 0.0 4.2 4 0 0 4 4 4 0 AAA domain dNK PF01712.19 RLN48222.1 - 0.078 12.8 0.2 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_5 PF07728.14 RLN48222.1 - 0.36 10.8 1.7 1.2 9.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) VWA_3 PF13768.6 RLN48222.1 - 0.37 10.7 3.4 5.1 7.0 0.1 3.5 3 0 0 3 3 2 0 von Willebrand factor type A domain Mog1 PF04603.12 RLN48224.1 - 7.3e-40 136.5 0.0 9.5e-40 136.2 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein TIP49 PF06068.13 RLN48225.1 - 1.1e-156 521.5 0.3 1.4e-156 521.2 0.3 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 RLN48225.1 - 3.5e-22 78.3 0.2 9.4e-22 76.9 0.2 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 RLN48225.1 - 7.8e-09 36.1 1.2 1.7e-05 25.2 0.0 3.3 3 1 1 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN48225.1 - 4.4e-06 27.0 0.3 0.01 16.1 0.0 2.7 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.12 RLN48225.1 - 5.2e-06 26.3 0.4 0.009 15.8 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RLN48225.1 - 0.001 19.1 0.3 0.11 12.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RLN48225.1 - 0.0022 18.4 0.4 0.046 14.1 0.0 2.7 1 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 RLN48225.1 - 0.0057 17.0 3.6 0.19 12.0 3.6 2.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 RLN48225.1 - 0.011 15.3 0.1 0.028 14.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 RLN48225.1 - 0.011 15.1 0.2 0.41 10.0 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 RLN48225.1 - 0.014 15.1 0.1 6.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 RLN48225.1 - 0.015 15.5 0.1 0.076 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 RLN48225.1 - 0.02 14.2 0.0 0.045 13.1 0.0 1.6 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ResIII PF04851.15 RLN48225.1 - 0.05 13.6 0.1 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ATPase PF06745.13 RLN48225.1 - 0.051 12.9 0.9 0.47 9.8 0.1 2.4 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 RLN48225.1 - 0.12 13.0 0.0 0.31 11.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 RLN48225.1 - 0.12 11.7 0.3 0.28 10.4 0.3 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 RLN48225.1 - 0.13 11.9 0.7 5.2 6.7 0.2 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RLN48225.1 - 0.13 11.7 0.1 0.52 9.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 RLN48225.1 - 0.17 11.8 0.1 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain PAN_4 PF14295.6 RLN48228.1 - 5.6e-28 96.6 31.9 4.8e-11 42.4 1.7 4.1 3 1 0 3 3 3 3 PAN domain PAN_1 PF00024.26 RLN48228.1 - 1.1e-15 57.3 7.2 0.00024 21.0 0.1 3.2 2 1 1 3 3 3 3 PAN domain PAN_2 PF08276.11 RLN48228.1 - 0.048 13.8 27.9 0.83 9.8 2.6 3.3 3 0 0 3 3 3 0 PAN-like domain Pkinase PF00069.25 RLN48230.1 - 1.6e-47 162.1 0.0 2.9e-47 161.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN48230.1 - 1.4e-42 145.8 0.0 1.9e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Podoplanin PF05808.11 RLN48230.1 - 0.00011 22.4 1.3 0.00022 21.4 1.3 1.5 1 0 0 1 1 1 1 Podoplanin DUF1180 PF06679.12 RLN48230.1 - 0.013 15.9 2.3 0.013 15.9 2.3 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) Adeno_E3_CR2 PF02439.15 RLN48230.1 - 0.017 14.8 1.1 0.033 13.9 1.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Protocadherin PF08374.11 RLN48230.1 - 0.031 14.2 0.3 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Protocadherin CTC1 PF15489.6 RLN48230.1 - 0.056 11.0 0.0 0.083 10.4 0.0 1.1 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 Haspin_kinase PF12330.8 RLN48230.1 - 0.064 12.2 0.2 0.2 10.6 0.2 1.7 1 1 0 1 1 1 0 Haspin like kinase domain TMEM154 PF15102.6 RLN48230.1 - 0.07 13.0 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family ECSCR PF15820.5 RLN48230.1 - 0.1 12.4 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator EphA2_TM PF14575.6 RLN48230.1 - 0.16 12.9 0.0 0.32 11.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MGC-24 PF05283.11 RLN48230.1 - 0.29 11.6 2.6 0.57 10.6 2.6 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin MtrF PF09472.10 RLN48230.1 - 0.64 9.5 5.3 1.3 8.5 5.3 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) PAN_4 PF14295.6 RLN48231.1 - 5e-48 160.8 50.3 1.4e-10 40.9 6.2 6.2 6 0 0 6 6 6 5 PAN domain PAN_1 PF00024.26 RLN48231.1 - 2.7e-26 91.3 21.7 1e-05 25.4 0.5 5.2 4 1 1 5 5 5 5 PAN domain PAN_2 PF08276.11 RLN48231.1 - 0.03 14.4 52.3 0.25 11.5 4.6 5.3 5 0 0 5 5 5 0 PAN-like domain MAAL_C PF07476.11 RLN48231.1 - 0.079 12.1 1.8 3.2 6.8 0.1 2.9 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus Sugar_tr PF00083.24 RLN48240.1 - 3.1e-40 138.4 20.7 4.6e-40 137.8 20.7 1.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN48240.1 - 1e-21 77.3 39.6 9e-16 57.7 20.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 RLN48240.1 - 0.00026 20.4 2.6 0.00026 20.4 2.6 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB CNDH2_C PF16858.5 RLN48241.1 - 8.9e-81 272.0 0.7 8.9e-81 272.0 0.7 2.7 3 1 0 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 RLN48241.1 - 2.4e-30 105.0 0.0 2.4e-30 105.0 0.0 2.5 3 0 0 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal MMR_HSR1 PF01926.23 RLN48242.1 - 6.3e-10 39.1 0.0 2.6e-09 37.2 0.0 1.9 1 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 RLN48242.1 - 1.2e-06 28.0 0.0 2.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 RLN48242.1 - 0.00032 20.7 0.0 0.0019 18.2 0.1 2.2 2 1 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 RLN48242.1 - 0.0028 18.1 0.0 0.0086 16.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 RLN48242.1 - 0.0039 17.7 0.0 0.013 16.0 0.0 1.9 2 1 0 2 2 2 1 ABC transporter AAA_18 PF13238.6 RLN48242.1 - 0.0074 16.8 0.0 0.022 15.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 RLN48242.1 - 0.0078 16.3 1.2 0.47 10.5 0.2 2.9 2 1 0 3 3 3 1 Dynamin family AAA_10 PF12846.7 RLN48242.1 - 0.0092 14.9 0.0 0.015 14.3 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain AAA PF00004.29 RLN48242.1 - 0.014 15.8 0.0 0.036 14.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) BMFP PF04380.13 RLN48242.1 - 0.017 15.6 2.2 11 6.6 2.6 2.7 1 1 1 2 2 2 0 Membrane fusogenic activity AAA_28 PF13521.6 RLN48242.1 - 0.02 15.1 1.0 1.3 9.2 0.0 2.7 2 1 1 3 3 3 0 AAA domain AAA_29 PF13555.6 RLN48242.1 - 0.027 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DivIC PF04977.15 RLN48242.1 - 0.037 13.8 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 Septum formation initiator AAA_17 PF13207.6 RLN48242.1 - 0.046 14.1 0.0 0.078 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain betaPIX_CC PF16523.5 RLN48242.1 - 0.079 12.8 0.5 0.67 9.8 0.2 2.4 3 0 0 3 3 3 0 betaPIX coiled coil FeoB_N PF02421.18 RLN48242.1 - 0.083 12.4 0.0 0.26 10.8 0.0 1.9 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 RLN48242.1 - 0.094 13.0 0.0 0.44 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 RLN48242.1 - 0.1 13.1 0.7 2.6 8.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain MutS_IV PF05190.18 RLN48242.1 - 0.14 12.5 0.7 7.8 6.9 0.1 2.3 2 0 0 2 2 2 0 MutS family domain IV AAA_19 PF13245.6 RLN48242.1 - 0.17 12.3 0.0 0.22 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 RLN48243.1 - 4e-10 39.8 0.6 4.3e-09 36.4 0.0 2.4 3 0 0 3 3 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 RLN48243.1 - 1.6e-06 27.6 0.0 2.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 AIG1 family DZR PF12773.7 RLN48243.1 - 1.9e-05 24.6 13.0 4.8e-05 23.3 13.0 1.7 1 1 0 1 1 1 1 Double zinc ribbon RsgA_GTPase PF03193.16 RLN48243.1 - 0.00038 20.4 0.0 0.00098 19.1 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 RLN48243.1 - 0.00097 19.6 0.1 0.0055 17.1 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain UPF0547 PF10571.9 RLN48243.1 - 0.0016 18.5 0.8 0.0016 18.5 0.8 2.1 2 0 0 2 2 2 1 Uncharacterised protein family UPF0547 ABC_tran PF00005.27 RLN48243.1 - 0.0033 18.0 0.0 0.0058 17.1 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA PF00004.29 RLN48243.1 - 0.0039 17.6 0.2 0.032 14.7 0.0 2.4 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 RLN48243.1 - 0.0057 16.4 0.0 0.03 14.1 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain zinc_ribbon_2 PF13240.6 RLN48243.1 - 0.0065 16.2 11.7 0.058 13.1 0.6 3.0 2 1 0 2 2 2 2 zinc-ribbon domain AAA_18 PF13238.6 RLN48243.1 - 0.0069 16.9 0.0 0.032 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 RLN48243.1 - 0.0076 15.7 0.0 0.27 10.7 0.0 2.3 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 RLN48243.1 - 0.015 15.3 1.3 0.55 10.3 0.2 2.8 2 1 1 3 3 3 0 Dynamin family NRBF2 PF08961.10 RLN48243.1 - 0.022 14.4 0.2 0.037 13.6 0.2 1.3 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator AAA_28 PF13521.6 RLN48243.1 - 0.022 15.0 0.4 1.6 8.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 RLN48243.1 - 0.023 14.4 0.1 8.2 6.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 RLN48243.1 - 0.026 14.8 0.0 0.36 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 RLN48243.1 - 0.038 14.4 0.0 0.11 12.9 0.0 1.9 1 1 1 2 2 2 0 AAA domain Septin PF00735.18 RLN48243.1 - 0.077 12.3 0.1 0.25 10.6 0.1 2.0 1 1 0 1 1 1 0 Septin DUF2353 PF09789.9 RLN48243.1 - 0.095 12.0 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) zf-ribbon_3 PF13248.6 RLN48243.1 - 0.1 12.1 0.4 0.1 12.1 0.4 2.7 2 1 0 2 2 2 0 zinc-ribbon domain FeoB_N PF02421.18 RLN48243.1 - 0.12 11.9 0.0 0.31 10.6 0.0 1.8 1 0 0 1 1 1 0 Ferrous iron transport protein B ZapB PF06005.12 RLN48243.1 - 0.12 12.8 0.5 0.25 11.8 0.5 1.5 1 0 0 1 1 1 0 Cell division protein ZapB AAA_19 PF13245.6 RLN48243.1 - 0.15 12.4 0.0 0.22 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain zinc_ribbon_15 PF17032.5 RLN48243.1 - 0.32 11.8 17.0 1.5 9.6 14.6 2.9 2 1 1 3 3 3 0 zinc-ribbon family DpnI PF06044.12 RLN48243.1 - 0.43 10.2 2.8 0.68 9.5 0.8 2.1 2 0 0 2 2 2 0 Dam-replacing family zf-P11 PF03854.14 RLN48243.1 - 3 7.6 6.9 9.3 6.0 0.3 2.4 1 1 0 2 2 2 0 P-11 zinc finger PhnA_Zn_Ribbon PF08274.12 RLN48243.1 - 9.5 6.3 8.4 0.6 10.1 1.5 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon DUF676 PF05057.14 RLN48250.1 - 1.3e-06 28.1 0.0 1.8e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_12 PF13087.6 RLN48251.1 - 5.7e-50 169.7 0.3 1.1e-49 168.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 RLN48251.1 - 4.2e-29 102.1 0.2 7.4e-15 55.4 0.2 2.6 1 1 1 2 2 2 2 AAA domain Dna2 PF08696.11 RLN48251.1 - 9.1e-24 84.4 0.0 1.4e-12 47.9 0.0 2.5 1 1 1 2 2 2 2 DNA replication factor Dna2 AAA_30 PF13604.6 RLN48251.1 - 1e-12 48.2 0.1 2.4e-12 47.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RLN48251.1 - 1.1e-08 35.6 0.1 3.1e-08 34.1 0.1 1.9 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 RLN48251.1 - 1.2e-05 25.2 1.1 0.038 13.7 0.0 3.8 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 RLN48251.1 - 0.00045 20.1 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 RLN48251.1 - 0.024 14.4 0.0 0.06 13.2 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Thioredoxin_16 PF18569.1 RLN48251.1 - 0.048 13.8 0.0 2.7 8.2 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin-like domain UvrD-helicase PF00580.21 RLN48251.1 - 0.13 11.7 0.2 0.54 9.7 0.0 2.0 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain B12D PF06522.11 RLN48252.1 - 3.8e-09 36.2 0.0 5.2e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit B12D PF06522.11 RLN48253.1 - 3.8e-09 36.2 0.0 5.2e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit B12D PF06522.11 RLN48254.1 - 1.7e-11 43.7 0.0 2.5e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit BT1 PF03092.16 RLN48255.1 - 6.5e-18 64.3 9.5 5.8e-12 44.6 0.1 3.2 3 0 0 3 3 3 3 BT1 family B12D PF06522.11 RLN48256.1 - 3.5e-09 36.3 0.0 4.6e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF1853 PF08907.11 RLN48257.1 - 3.2e-21 76.3 0.0 3.1e-20 73.1 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1853) DNA_pol_A_exo1 PF01612.20 RLN48257.1 - 1.9e-13 50.5 0.1 6.3e-13 48.8 0.0 2.0 2 0 0 2 2 2 1 3'-5' exonuclease GIT_CC PF16559.5 RLN48258.1 - 0.12 12.2 2.5 1.3 8.9 0.1 2.9 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor ATG16 PF08614.11 RLN48258.1 - 2.2 8.5 21.3 6.4 6.9 20.9 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) YabA PF06156.13 RLN48258.1 - 8.3 7.1 8.3 9.4 6.9 0.1 3.3 1 1 2 3 3 3 0 Initiation control protein YabA ATP-synt_ab PF00006.25 RLN48259.1 - 9.2e-106 352.2 0.0 1.4e-105 351.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 RLN48259.1 - 2.6e-40 137.0 0.0 4.7e-40 136.2 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 RLN48259.1 - 1.8e-07 31.6 0.1 7.6e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_18 PF13238.6 RLN48259.1 - 0.086 13.4 0.0 0.21 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Metallophos PF00149.28 RLN48260.1 - 7.2e-28 98.5 0.2 1.2e-27 97.8 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 RLN48260.1 - 9e-09 35.7 0.1 3.8e-07 30.5 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN48260.1 - 1e-08 34.4 1.6 0.0001 21.9 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 RLN48260.1 - 1.7e-08 33.4 3.8 3.4e-05 23.1 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 RLN48260.1 - 1e-05 24.8 5.7 2.3e-05 23.7 0.1 3.0 3 0 0 3 3 3 1 EF hand PPP5 PF08321.12 RLN48260.1 - 0.00011 22.4 0.0 0.00022 21.4 0.0 1.5 1 0 0 1 1 1 1 PPP5 TPR repeat region EF-hand_8 PF13833.6 RLN48260.1 - 0.00049 19.9 1.8 0.019 14.8 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain pair Alg6_Alg8 PF03155.15 RLN48261.1 - 5.9e-158 526.8 25.3 6.8e-158 526.6 25.3 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family COPIIcoated_ERV PF07970.12 RLN48262.1 - 8e-25 88.0 0.1 1.3e-24 87.3 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Thioredoxin PF00085.20 RLN48262.1 - 0.0069 16.3 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin TPR_2 PF07719.17 RLN48263.1 - 5.1e-05 23.1 4.7 0.24 11.6 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN48263.1 - 0.0027 17.4 2.7 12 5.9 0.2 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN48263.1 - 0.004 17.9 4.4 0.23 12.4 0.2 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN48263.1 - 0.0076 16.4 0.1 0.42 10.9 0.0 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN48263.1 - 0.0086 16.7 3.2 4.2 8.1 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN48263.1 - 0.012 15.8 0.5 0.012 15.8 0.5 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 RLN48263.1 - 0.033 13.9 0.1 16 5.3 0.1 3.3 2 1 1 3 3 3 0 TPR repeat cNMP_binding PF00027.29 RLN48266.1 - 5.9e-44 148.1 0.1 2.8e-21 75.4 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF4150 PF13665.6 RLN48266.1 - 0.32 11.2 1.1 0.63 10.2 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4150) PX PF00787.24 RLN48268.1 - 8.5e-12 45.1 3.1 6.4e-05 22.9 0.1 2.4 2 0 0 2 2 2 2 PX domain Ank_2 PF12796.7 RLN48269.1 - 5.9e-28 97.3 5.3 2.2e-10 41.0 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN48269.1 - 2.7e-24 85.2 3.0 2.8e-09 37.3 0.0 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN48269.1 - 3.1e-24 84.3 5.1 0.00011 22.5 0.1 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 RLN48269.1 - 4.4e-24 81.9 1.9 0.00021 21.5 0.2 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 RLN48269.1 - 1.4e-17 63.5 7.6 0.00048 20.4 0.2 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) U-box PF04564.15 RLN48269.1 - 3.2e-14 52.9 0.0 7.9e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 RLN48269.1 - 0.00095 18.9 0.0 0.0025 17.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Ribosomal_60s PF00428.19 RLN48269.1 - 3.2 8.4 13.1 0.78 10.4 0.5 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein Glyco_hydro81C PF17652.1 RLN48270.1 - 4.5e-115 384.6 0.5 6.2e-115 384.2 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 RLN48270.1 - 1.3e-50 172.5 0.1 2.2e-50 171.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Cystatin PF00031.21 RLN48270.1 - 0.0062 16.8 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Cystatin domain PX PF00787.24 RLN48271.1 - 6.4e-10 39.0 0.1 3.3e-09 36.7 0.0 2.1 2 1 0 2 2 2 1 PX domain Myosin_head PF00063.21 RLN48272.1 - 3.2e-209 696.5 1.2 3.2e-209 696.5 1.2 2.0 2 0 0 2 2 2 1 Myosin head (motor domain) AAA_16 PF13191.6 RLN48272.1 - 0.0059 17.0 0.1 0.048 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Myosin_N PF02736.19 RLN48272.1 - 0.056 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain IQ PF00612.27 RLN48272.1 - 0.42 10.5 39.3 0.051 13.4 0.8 5.9 6 0 0 6 6 6 0 IQ calmodulin-binding motif AAA_22 PF13401.6 RLN48272.1 - 0.66 10.2 0.0 0.66 10.2 0.0 3.3 4 0 0 4 4 4 0 AAA domain MatP_C PF17414.2 RLN48272.1 - 3.7 7.8 7.4 0.79 10.0 2.0 2.6 2 0 0 2 2 2 0 MatP C-terminal ribbon-helix-helix domain XkdW PF09636.10 RLN48272.1 - 4.3 7.5 9.2 16 5.7 1.3 3.7 3 0 0 3 3 3 0 XkdW protein HA2 PF04408.23 RLN48273.1 - 6.2e-20 71.5 0.1 2.2e-19 69.7 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RLN48273.1 - 8.7e-18 64.5 0.0 2.5e-17 63.0 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 RLN48273.1 - 3.2e-11 43.6 0.0 7.6e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RLN48273.1 - 1.1e-05 25.3 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RLN48273.1 - 9.8e-05 22.7 0.0 0.00028 21.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 RLN48273.1 - 0.046 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 RLN48273.1 - 0.07 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 RLN48273.1 - 0.075 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 RLN48273.1 - 0.15 11.8 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_S25 PF03297.15 RLN48274.1 - 1.6e-39 134.2 5.0 1.9e-39 133.9 5.0 1.1 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.7 RLN48274.1 - 0.0059 16.5 0.2 0.0095 15.8 0.2 1.3 1 0 0 1 1 1 1 MarR family DDRGK PF09756.9 RLN48274.1 - 0.0096 15.5 0.4 0.014 15.0 0.4 1.3 1 0 0 1 1 1 1 DDRGK domain TrmB PF01978.19 RLN48274.1 - 0.019 14.9 0.2 0.028 14.3 0.2 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_DeoR PF08220.12 RLN48274.1 - 0.038 13.7 0.2 0.086 12.6 0.1 1.6 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain MarR PF01047.22 RLN48274.1 - 0.12 12.3 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 MarR family Fer4_19 PF06902.11 RLN48275.1 - 0.017 15.2 0.2 0.035 14.2 0.2 1.5 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster SUR7 PF06687.12 RLN48276.1 - 3 7.4 6.3 14 5.2 5.4 2.3 2 1 0 2 2 2 0 SUR7/PalI family Aldose_epim PF01263.20 RLN48277.1 - 3.7e-39 134.8 0.0 4.4e-39 134.6 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DTC PF18102.1 RLN48277.1 - 0.079 13.1 0.0 0.2 11.8 0.0 1.7 2 0 0 2 2 2 0 Deltex C-terminal domain Alginate_lyase PF05426.12 RLN48278.1 - 2.1e-14 53.7 1.7 3.5e-14 53.0 1.7 1.3 1 0 0 1 1 1 1 Alginate lyase SprT-like PF10263.9 RLN48279.1 - 8.3e-07 28.9 1.8 1.7e-06 27.9 1.8 1.4 1 0 0 1 1 1 1 SprT-like family DUF4852 PF16144.5 RLN48279.1 - 0.11 12.6 1.8 0.23 11.6 1.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4852) STAG PF08514.11 RLN48279.1 - 3 7.8 5.7 5.3 7.0 5.7 1.4 1 0 0 1 1 1 0 STAG domain TPH PF13868.6 RLN48280.1 - 2.3e-48 164.5 132.3 2.3e-48 164.5 132.3 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain PIN_6 PF17146.4 RLN48281.1 - 3e-29 101.3 0.2 1.1e-28 99.5 0.0 1.9 2 0 0 2 2 2 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 RLN48281.1 - 1.2e-26 92.6 0.5 2.1e-26 91.9 0.5 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-CCCH_4 PF18044.1 RLN48281.1 - 2.7e-08 33.4 13.2 0.00013 21.7 1.4 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 RLN48281.1 - 5.2e-08 32.6 10.9 0.0001 22.1 1.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 RLN48281.1 - 9.1e-07 29.1 15.5 0.0003 21.1 4.7 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 RLN48281.1 - 0.00051 20.0 12.9 0.036 14.1 2.1 2.9 2 1 0 2 2 2 2 Zinc finger domain DUF5620 PF18522.1 RLN48281.1 - 0.0048 17.3 0.0 0.014 15.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5620) zf-CCCH_3 PF15663.5 RLN48281.1 - 0.093 13.0 4.2 0.73 10.1 0.1 2.3 1 1 1 2 2 2 0 Zinc-finger containing family Ral PF11058.8 RLN48281.1 - 0.17 11.5 1.2 6.8 6.3 0.1 2.7 1 1 1 2 2 2 0 Antirestriction protein Ral Torus PF16131.5 RLN48281.1 - 0.17 12.6 8.9 3.1 8.5 1.0 2.8 2 1 1 3 3 3 0 Torus domain oligo_HPY PF08352.12 RLN48281.1 - 0.29 11.7 1.3 29 5.3 0.2 2.5 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region Peptidase_S15 PF02129.18 RLN48313.1 - 3.5e-55 187.5 2.9 5.6e-55 186.8 2.9 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 RLN48313.1 - 3.4e-34 118.8 1.2 3.6e-34 118.7 0.1 1.6 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 RLN48313.1 - 1.8e-09 37.2 0.0 3.6e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 RLN48313.1 - 3.2e-06 26.8 0.8 7.2e-06 25.6 0.3 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 RLN48313.1 - 7.4e-06 25.8 0.2 1.5e-05 24.8 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1579 PF07617.11 RLN48313.1 - 0.006 16.5 0.1 0.036 14.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1579) Abhydrolase_6 PF12697.7 RLN48313.1 - 0.056 14.0 8.2 0.12 13.0 7.6 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family WD40 PF00400.32 RLN48315.1 - 6.5e-06 26.8 11.9 0.096 13.6 0.1 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat MAP65_ASE1 PF03999.12 RLN48316.1 - 0.41 9.3 3.9 0.5 9.0 3.9 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Adaptin_N PF01602.20 RLN48320.1 - 4e-144 481.0 15.7 8.1e-137 456.9 11.1 2.1 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 RLN48320.1 - 1.4e-67 226.8 4.6 1.4e-65 220.2 0.1 3.1 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 RLN48320.1 - 8.3e-25 87.1 0.4 4.4e-24 84.7 0.1 2.3 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 RLN48320.1 - 8.6e-18 64.5 4.8 6.7e-05 23.2 0.0 5.7 2 2 3 5 5 5 5 HEAT repeats HEAT PF02985.22 RLN48320.1 - 6.9e-11 41.4 4.9 0.0024 18.0 0.0 6.3 6 0 0 6 6 6 2 HEAT repeat Cnd3 PF12719.7 RLN48320.1 - 5.1e-08 32.5 0.7 4.6e-05 22.8 0.2 2.8 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 RLN48320.1 - 2.3e-06 27.5 1.0 0.02 14.9 0.0 4.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 RLN48320.1 - 1.3e-05 24.8 0.0 4.3e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Armadillo-like Alpha_adaptinC2 PF02883.20 RLN48320.1 - 3e-05 24.3 1.5 7.3e-05 23.1 1.5 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain UNC45-central PF11701.8 RLN48320.1 - 3.8e-05 23.7 0.4 0.11 12.4 0.0 3.7 3 1 0 3 3 3 2 Myosin-binding striated muscle assembly central DUF3157 PF11355.8 RLN48320.1 - 0.00019 21.1 1.9 0.00089 18.9 0.1 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF3157) CLASP_N PF12348.8 RLN48320.1 - 0.001 18.7 3.2 1.2 8.6 0.0 3.7 2 2 1 3 3 3 2 CLASP N terminal RTP1_C1 PF10363.9 RLN48320.1 - 0.0015 18.7 3.7 2.8 8.2 0.0 4.7 2 2 3 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF5578 PF17741.1 RLN48320.1 - 0.0069 15.8 2.6 2.8 7.3 0.0 4.2 4 1 0 4 4 4 1 Family of unknown function (DUF5578) AP3B1_C PF14796.6 RLN48320.1 - 0.0083 16.4 0.0 0.028 14.7 0.0 2.0 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal HEAT_EZ PF13513.6 RLN48320.1 - 0.016 15.7 4.0 3.4 8.3 0.0 4.9 7 0 0 7 7 6 0 HEAT-like repeat RasGEF_N_2 PF14663.6 RLN48320.1 - 0.3 11.5 1.6 26 5.3 0.0 4.1 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF3361 PF11841.8 RLN48320.1 - 1.9 8.4 4.6 20 5.1 0.2 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3361) CAP_N PF01213.19 RLN48321.1 - 0.0061 16.1 1.1 0.0061 16.1 1.1 1.5 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal DSBA PF01323.20 RLN48321.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 DSBA-like thioredoxin domain PRIMA1 PF16101.5 RLN48321.1 - 2 8.4 9.1 4.5 7.3 9.1 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 FAR1 PF03101.15 RLN48322.1 - 0.017 15.8 1.5 0.021 15.5 0.4 1.7 2 0 0 2 2 2 0 FAR1 DNA-binding domain T2SSF PF00482.23 RLN48322.1 - 0.042 13.8 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Arm PF00514.23 RLN48323.1 - 1.2e-32 110.9 11.2 0.00013 21.9 0.0 7.7 7 0 0 7 7 7 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN48323.1 - 3.5e-05 24.2 14.2 0.0019 18.7 0.8 5.5 3 2 2 5 5 5 3 HEAT-like repeat Atx10homo_assoc PF09759.9 RLN48323.1 - 0.00073 19.5 0.2 5.2 7.1 0.0 4.0 2 1 3 5 5 5 3 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 RLN48323.1 - 0.011 16.1 22.0 0.064 13.7 2.1 4.5 2 1 5 7 7 7 0 HEAT repeats HEAT PF02985.22 RLN48323.1 - 0.013 15.7 6.0 3.3 8.2 0.2 6.1 8 0 0 8 8 8 0 HEAT repeat KLRAQ PF10205.9 RLN48323.1 - 0.069 13.4 1.2 0.19 12.0 0.9 1.9 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein Arm_2 PF04826.13 RLN48323.1 - 0.084 12.3 0.1 2.9 7.3 0.1 2.9 2 1 1 3 3 3 0 Armadillo-like FYVE PF01363.21 RLN48325.1 - 0.31 11.2 7.5 0.64 10.2 7.5 1.5 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN48325.1 - 1 9.6 7.7 2.5 8.3 7.7 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-BED PF02892.15 RLN48326.1 - 0.001 19.1 0.1 0.0021 18.0 0.1 1.5 1 0 0 1 1 1 1 BED zinc finger DUF3046 PF11248.8 RLN48326.1 - 0.0038 17.6 0.0 0.0083 16.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3046) LexA_DNA_bind PF01726.16 RLN48326.1 - 0.13 12.0 0.0 0.84 9.5 0.0 2.3 2 0 0 2 2 2 0 LexA DNA binding domain SRC-1 PF08832.10 RLN48326.1 - 0.44 11.6 0.0 0.44 11.6 0.0 3.1 3 1 0 3 3 3 0 Steroid receptor coactivator Pro_isomerase PF00160.21 RLN48327.1 - 3.7e-13 50.0 0.0 4e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LRR_6 PF13516.6 RLN48328.1 - 6.1e-41 135.0 30.2 0.0011 18.9 0.0 16.1 16 0 0 16 16 16 11 Leucine Rich repeat LRR_4 PF12799.7 RLN48328.1 - 8.9e-06 26.0 18.4 2.9 8.4 0.0 10.2 9 2 2 12 12 12 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN48328.1 - 2e-05 24.5 17.3 28 5.8 0.1 12.2 14 2 0 14 14 14 1 Leucine Rich Repeat HHH_5 PF14520.6 RLN48328.1 - 0.052 14.2 0.1 3.6 8.3 0.0 3.4 3 0 0 3 3 3 0 Helix-hairpin-helix domain LRR_8 PF13855.6 RLN48328.1 - 1.4 8.7 29.0 0.82 9.5 3.4 8.1 7 2 2 9 9 9 0 Leucine rich repeat Cyt-b5 PF00173.28 RLN48337.1 - 1.4e-12 47.6 0.0 2.6e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ABA_GPCR PF12430.8 RLN48362.1 - 2e-23 83.1 7.0 2e-23 83.1 7.0 2.2 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 RLN48362.1 - 7.4e-20 70.8 0.0 2.1e-19 69.3 0.0 1.8 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal Ank_2 PF12796.7 RLN48363.1 - 3.6e-23 82.0 3.1 4.1e-08 33.7 0.1 4.2 2 1 5 7 7 7 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN48363.1 - 1.3e-14 54.1 7.5 0.0015 18.8 0.0 6.6 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN48363.1 - 4.4e-14 52.6 10.5 6.3e-07 29.8 0.2 6.9 5 3 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN48363.1 - 9.2e-06 25.6 10.4 5 8.0 0.0 7.6 8 1 1 9 9 9 2 Ankyrin repeat DUF5049 PF16468.5 RLN48363.1 - 0.0013 18.6 0.1 10 6.1 0.0 3.9 2 1 2 4 4 4 2 Domain of unknown function (DUF5049) Ank PF00023.30 RLN48363.1 - 6 7.5 7.6 65 4.2 0.1 4.9 4 2 2 6 6 6 0 Ankyrin repeat DDE_3 PF13358.6 RLN48365.1 - 0.14 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease Pkinase PF00069.25 RLN48372.1 - 7.8e-67 225.4 0.0 1.2e-66 224.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN48372.1 - 4.7e-32 111.3 0.0 1.4e-31 109.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase PH PF00169.29 RLN48372.1 - 8.1e-09 35.9 0.1 2.3e-08 34.5 0.1 1.9 1 0 0 1 1 1 1 PH domain Kdo PF06293.14 RLN48372.1 - 0.00016 21.1 0.2 0.00033 20.1 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RLN48372.1 - 0.0077 15.2 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain C2 PF00168.30 RLN48372.1 - 0.022 15.0 0.0 0.075 13.3 0.0 1.9 1 0 0 1 1 1 0 C2 domain Multi_ubiq PF14452.6 RLN48372.1 - 0.023 14.9 0.0 0.08 13.2 0.0 2.0 1 0 0 1 1 1 0 Multiubiquitin Pkinase_fungal PF17667.1 RLN48372.1 - 0.029 13.2 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 RLN48372.1 - 0.036 14.0 0.2 0.17 11.7 0.2 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Peptidase_S41 PF03572.18 RLN48372.1 - 0.11 12.0 0.2 0.22 11.1 0.2 1.4 1 0 0 1 1 1 0 Peptidase family S41 HTH_33 PF13592.6 RLN48378.1 - 0.00042 19.9 0.1 0.00082 19.0 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix DUF3860 PF12976.7 RLN48378.1 - 0.021 14.8 0.5 1 9.4 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) MIR PF02815.19 RLN48378.1 - 0.12 12.2 0.4 2.3 8.1 0.0 2.5 1 1 1 2 2 2 0 MIR domain RskA PF10099.9 RLN48382.1 - 0.064 13.5 0.7 0.12 12.6 0.7 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA RskA PF10099.9 RLN48384.1 - 0.069 13.4 0.7 0.12 12.6 0.7 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA WD40 PF00400.32 RLN48385.1 - 4.1e-13 49.6 12.7 0.0027 18.5 0.1 8.4 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN48385.1 - 0.00023 21.4 1.5 2.2 8.6 0.1 5.1 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_7 PF13499.6 RLN48385.1 - 0.087 13.3 0.0 10 6.6 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain pair Peptidase_S80 PF07230.11 RLN48385.1 - 0.1 10.9 0.0 0.16 10.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) EF-hand_6 PF13405.6 RLN48385.1 - 0.14 12.1 0.0 2 8.6 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain LCAT PF02450.15 RLN48386.1 - 7.3e-05 22.1 0.3 0.36 9.9 0.1 2.2 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 RLN48386.1 - 0.0006 20.5 0.1 2 9.0 0.0 2.6 2 1 0 2 2 2 2 Alpha/beta hydrolase family PGAP1 PF07819.13 RLN48386.1 - 0.012 15.3 0.1 7.2 6.3 0.0 2.6 2 0 0 2 2 2 0 PGAP1-like protein Plug PF07715.15 RLN48386.1 - 0.017 15.7 0.1 2.2 8.9 0.0 2.6 2 0 0 2 2 2 0 TonB-dependent Receptor Plug Domain DUF900 PF05990.12 RLN48386.1 - 0.058 12.9 0.0 16 4.9 0.0 2.6 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 RLN48386.1 - 0.076 12.3 0.1 13 4.9 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 SWIM PF04434.17 RLN48386.1 - 0.093 12.4 2.6 10 5.9 0.2 2.7 2 0 0 2 2 2 0 SWIM zinc finger RabGAP-TBC PF00566.18 RLN48387.1 - 7.2e-09 35.6 0.3 1.3e-08 34.8 0.3 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Gp58 PF07902.11 RLN48387.1 - 0.14 10.4 0.2 0.25 9.6 0.2 1.4 1 0 0 1 1 1 0 gp58-like protein Acetyltransf_3 PF13302.7 RLN48388.1 - 2.3e-13 51.0 0.0 2.5e-13 50.9 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 RLN48388.1 - 0.017 14.8 0.0 0.018 14.8 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RLN48388.1 - 0.021 15.0 0.0 0.022 15.0 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Birna_VP3 PF01767.16 RLN48388.1 - 0.12 12.5 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Birnavirus VP3 protein Strep_SA_rep PF06696.11 RLN48389.1 - 0.00035 20.5 4.7 0.0017 18.3 4.7 2.2 1 0 0 1 1 1 1 Streptococcal surface antigen repeat DUF3304 PF11745.8 RLN48389.1 - 0.51 10.8 4.1 17 5.9 0.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3304) NUC153 PF08159.12 RLN48407.1 - 5.3e-11 42.1 1.2 1.2e-10 41.0 1.2 1.6 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 RLN48407.1 - 1.9e-05 24.9 0.0 0.19 12.0 0.0 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 RLN48407.1 - 0.023 13.3 0.0 0.045 12.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain SAPS PF04499.15 RLN48407.1 - 0.74 8.5 5.0 1.1 8.0 5.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 RLN48407.1 - 0.98 7.6 16.5 1.6 7.0 16.5 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 RLN48407.1 - 2.8 7.2 30.2 5 6.4 30.3 1.3 1 1 0 1 1 1 0 BUD22 Dzip-like_N PF13815.6 RLN48408.1 - 1.4e-12 47.6 0.0 1.5e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal Arm PF00514.23 RLN48412.1 - 2.5e-11 43.2 36.6 0.00041 20.3 0.0 12.6 12 1 0 13 13 13 5 Armadillo/beta-catenin-like repeat DUF383 PF04063.14 RLN48412.1 - 0.0064 16.2 0.2 5.3 6.7 0.1 3.6 2 2 0 2 2 2 2 Domain of unknown function (DUF383) HEAT_2 PF13646.6 RLN48412.1 - 0.0098 16.3 0.3 0.34 11.3 0.1 3.6 2 0 0 2 2 2 1 HEAT repeats Arm_2 PF04826.13 RLN48412.1 - 0.14 11.6 3.5 0.53 9.7 0.8 3.0 3 0 0 3 3 3 0 Armadillo-like HEAT_EZ PF13513.6 RLN48412.1 - 1.1 9.9 10.0 0.93 10.1 0.6 4.9 4 0 0 4 4 4 0 HEAT-like repeat Xpo1 PF08389.12 RLN48414.1 - 4.1e-17 62.6 0.1 7.3e-17 61.8 0.1 1.4 1 0 0 1 1 1 1 Exportin 1-like protein SAA PF00277.18 RLN48414.1 - 0.037 14.5 0.0 0.072 13.6 0.0 1.5 1 0 0 1 1 1 0 Serum amyloid A protein UNC45-central PF11701.8 RLN48415.1 - 0.0024 17.8 0.5 0.023 14.6 0.1 2.8 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central cNMP_binding PF00027.29 RLN48415.1 - 0.15 12.2 0.0 0.57 10.3 0.0 2.0 1 1 0 1 1 1 0 Cyclic nucleotide-binding domain ABC_tran PF00005.27 RLN48416.1 - 5.4e-69 231.0 0.1 5.1e-28 98.3 0.0 4.5 3 1 1 4 4 4 4 ABC transporter ABC_membrane PF00664.23 RLN48416.1 - 3.9e-58 197.3 33.5 1.1e-33 117.1 6.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region MMR_HSR1 PF01926.23 RLN48416.1 - 1.1e-13 51.2 0.7 0.0073 16.4 0.2 4.5 4 0 0 4 4 4 3 50S ribosome-binding GTPase AAA_21 PF13304.6 RLN48416.1 - 1.3e-10 41.6 5.0 0.19 11.5 0.0 5.0 5 1 1 6 6 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RLN48416.1 - 2.7e-08 33.5 5.2 0.014 14.8 0.0 5.1 4 1 1 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RLN48416.1 - 5.7e-08 32.4 0.9 0.16 11.7 0.0 3.5 3 0 0 3 3 3 3 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN48416.1 - 2.9e-07 31.2 1.7 1 9.8 0.0 3.6 4 0 0 4 4 3 3 AAA domain DUF87 PF01935.17 RLN48416.1 - 5.4e-07 29.9 3.9 0.04 14.0 0.1 3.6 3 0 0 3 3 3 2 Helicase HerA, central domain RsgA_GTPase PF03193.16 RLN48416.1 - 2.3e-06 27.6 5.4 0.063 13.2 0.2 4.1 4 0 0 4 4 3 2 RsgA GTPase AAA_24 PF13479.6 RLN48416.1 - 5.6e-06 26.2 0.3 0.06 13.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 RLN48416.1 - 6.6e-06 26.6 1.7 0.053 13.9 0.0 3.7 3 1 0 3 3 3 1 AAA ATPase domain Dynamin_N PF00350.23 RLN48416.1 - 6.1e-05 23.1 4.1 0.042 13.9 0.1 3.6 4 0 0 4 4 3 1 Dynamin family AAA_7 PF12775.7 RLN48416.1 - 6.3e-05 22.6 0.1 0.42 10.1 0.0 3.3 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_22 PF13401.6 RLN48416.1 - 7e-05 23.1 1.3 7.7 6.8 0.1 4.1 4 1 0 4 4 3 0 AAA domain AAA_18 PF13238.6 RLN48416.1 - 9.4e-05 23.0 0.1 8.6 6.9 0.0 3.8 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 RLN48416.1 - 0.0005 20.3 0.4 7.7 6.8 0.0 3.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 RLN48416.1 - 0.00063 19.5 3.4 4.2 7.1 0.0 4.6 5 0 0 5 5 4 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 RLN48416.1 - 0.00072 18.9 0.3 0.079 12.2 0.2 3.2 3 0 0 3 3 3 1 Zeta toxin AAA_25 PF13481.6 RLN48416.1 - 0.0011 18.5 0.2 1.8 8.1 0.0 3.6 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.13 RLN48416.1 - 0.0016 17.6 3.4 0.63 9.2 0.1 3.8 4 0 0 4 4 4 1 Protein of unknown function (DUF815) cobW PF02492.19 RLN48416.1 - 0.0048 16.5 0.8 3.9 7.0 0.1 3.7 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.29 RLN48416.1 - 0.0073 16.1 2.1 0.24 11.2 0.0 3.3 3 1 0 3 3 2 1 DEAD/DEAH box helicase Ploopntkinase3 PF18751.1 RLN48416.1 - 0.013 15.5 0.2 15 5.4 0.1 3.4 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 RLN48416.1 - 0.015 15.5 0.0 2.9 8.0 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 RLN48416.1 - 0.016 14.9 0.1 23 4.5 0.1 3.5 3 0 0 3 3 3 0 AAA ATPase domain CbiA PF01656.23 RLN48416.1 - 0.017 15.2 0.0 15 5.7 0.0 3.8 4 1 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.22 RLN48416.1 - 0.038 14.4 1.1 89 3.5 0.0 3.9 4 0 0 4 4 3 0 RNA helicase TsaE PF02367.17 RLN48416.1 - 0.043 13.8 0.2 5.4 7.0 0.0 3.2 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 RLN48416.1 - 0.056 12.7 0.1 7.3 5.8 0.0 3.1 3 0 0 3 3 3 0 Septin AAA_28 PF13521.6 RLN48416.1 - 0.062 13.5 0.1 1.2 9.3 0.0 3.2 4 0 0 4 4 3 0 AAA domain TrwB_AAD_bind PF10412.9 RLN48416.1 - 0.13 11.1 1.2 20 3.9 0.0 3.1 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain GTP_EFTU PF00009.27 RLN48416.1 - 0.14 11.7 0.4 27 4.2 0.0 3.3 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AIG1 PF04548.16 RLN48416.1 - 0.15 11.4 1.4 10 5.3 0.3 3.2 3 0 0 3 3 3 0 AIG1 family MeaB PF03308.16 RLN48416.1 - 0.15 11.0 1.8 31 3.4 0.0 3.3 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_10 PF12846.7 RLN48416.1 - 0.16 10.8 0.2 9.7 5.0 0.0 3.0 3 0 0 3 3 3 0 AAA-like domain FtsK_SpoIIIE PF01580.18 RLN48416.1 - 0.64 9.3 4.0 57 2.9 0.0 3.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 RLN48416.1 - 0.66 9.7 3.1 82 2.9 0.1 3.8 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein ZapB PF06005.12 RLN48417.1 - 0.22 12.0 2.5 0.98 9.9 2.5 2.1 1 1 0 1 1 1 0 Cell division protein ZapB PriC PF07445.12 RLN48417.1 - 1.2 9.1 6.7 11 5.9 6.5 2.1 1 1 0 1 1 1 0 Primosomal replication protein priC bZIP_2 PF07716.15 RLN48417.1 - 2.4 8.3 7.3 1.6 8.9 5.0 1.9 2 0 0 2 2 2 0 Basic region leucine zipper Bap31_Bap29_C PF18035.1 RLN48420.1 - 2.9 8.0 0.0 2.9 8.0 0.0 17.3 19 3 2 21 21 21 0 Bap31/Bap29 cytoplasmic coiled-coil domain Tyrosinase PF00264.20 RLN48421.1 - 2.3e-10 41.1 0.0 6.7e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 Common central domain of tyrosinase DUF4530 PF15039.6 RLN48422.1 - 0.011 15.9 3.9 0.011 15.9 3.9 5.4 4 3 2 6 6 6 0 Domain of unknown function (DUF4530) Abhydrolase_1 PF00561.20 RLN48423.1 - 5.3e-22 78.7 0.0 6e-21 75.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN48423.1 - 1.4e-12 47.4 0.0 1.9e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN48423.1 - 8.1e-12 46.2 0.3 1.1e-11 45.7 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 RLN48423.1 - 0.0005 19.7 0.0 0.00073 19.2 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 RLN48423.1 - 0.02 14.6 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 RLN48423.1 - 0.14 11.7 0.0 0.61 9.5 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family FAM177 PF14774.6 RLN48423.1 - 0.19 12.1 0.0 0.35 11.2 0.0 1.3 1 0 0 1 1 1 0 FAM177 family Abhydrolase_1 PF00561.20 RLN48424.1 - 3.4e-17 62.9 0.0 8.7e-13 48.5 0.1 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN48424.1 - 1.1e-05 24.9 0.0 2.8e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN48424.1 - 0.00012 22.8 0.5 0.00016 22.3 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 RLN48424.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Type_III_YscG PF09477.10 RLN48427.1 - 0.21 11.7 1.9 0.7 10.0 0.1 2.6 3 0 0 3 3 3 0 Bacterial type II secretion system chaperone protein (type_III_yscG) PX PF00787.24 RLN48428.1 - 1.9e-07 31.1 0.2 4.4e-07 29.9 0.2 1.6 1 0 0 1 1 1 1 PX domain rRNA_proc-arch PF13234.6 RLN48431.1 - 3.5e-68 230.5 1.3 6.9e-68 229.5 1.3 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 RLN48431.1 - 5e-50 169.4 0.5 5e-50 169.4 0.5 2.2 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 RLN48431.1 - 2.6e-18 66.4 0.0 1.1e-17 64.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN48431.1 - 8e-07 29.4 0.2 3.6e-05 24.1 0.0 3.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain FBPase_3 PF01950.16 RLN48431.1 - 0.045 12.9 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 Fructose-1,6-bisphosphatase ATPase_2 PF01637.18 RLN48431.1 - 0.064 13.2 0.9 0.31 10.9 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Dimer_Tnp_hAT PF05699.14 RLN48432.1 - 1.7e-12 47.0 0.1 3.3e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Abhydrolase_1 PF00561.20 RLN48433.1 - 1.4e-21 77.3 0.0 4.4e-17 62.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN48433.1 - 7.9e-12 46.2 0.2 1.5e-11 45.3 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN48433.1 - 1.3e-10 41.0 0.0 2.3e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 RLN48433.1 - 0.0076 15.8 0.0 0.021 14.4 0.0 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family Ndr PF03096.14 RLN48433.1 - 0.026 13.2 0.0 0.038 12.7 0.0 1.2 1 0 0 1 1 1 0 Ndr family Abhydrolase_1 PF00561.20 RLN48434.1 - 5.1e-16 59.1 0.0 5.7e-13 49.1 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN48434.1 - 7.4e-13 48.3 0.1 1.1e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN48434.1 - 1.1e-11 45.7 0.0 1.6e-11 45.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 RLN48434.1 - 0.00042 19.9 0.0 0.00071 19.2 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 RLN48435.1 - 1.4e-24 87.1 0.0 4.1e-21 75.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN48435.1 - 1e-17 65.5 0.1 1.4e-17 65.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN48435.1 - 2.8e-13 49.7 0.3 6.2e-12 45.3 0.3 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 RLN48435.1 - 3.1e-07 30.2 0.0 0.00066 19.3 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 RLN48435.1 - 4.4e-05 23.5 0.0 0.00016 21.7 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein Thioesterase PF00975.20 RLN48435.1 - 8.5e-05 22.8 0.0 0.00019 21.6 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 RLN48435.1 - 0.00027 20.7 0.0 0.068 12.9 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 RLN48435.1 - 0.001 18.9 0.0 0.34 10.7 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 RLN48435.1 - 0.004 17.0 0.0 0.009 15.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN48435.1 - 0.0068 15.9 0.2 0.043 13.3 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.13 RLN48435.1 - 0.014 15.0 0.1 0.27 10.9 0.3 2.5 2 1 0 2 2 2 0 Serine hydrolase (FSH1) BAAT_C PF08840.11 RLN48435.1 - 0.053 13.4 0.1 0.58 10.0 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.14 RLN48435.1 - 0.077 12.3 0.0 0.66 9.2 0.0 2.0 2 0 0 2 2 2 0 Secretory lipase DUF1100 PF06500.11 RLN48435.1 - 0.078 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Esterase PF00756.20 RLN48435.1 - 0.088 12.4 0.1 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Putative esterase PGAP1 PF07819.13 RLN48435.1 - 0.1 12.3 0.1 0.84 9.3 0.1 2.1 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_1 PF00561.20 RLN48436.1 - 1.2e-20 74.2 0.0 8.2e-16 58.4 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN48436.1 - 3.7e-12 47.3 0.4 5.7e-12 46.7 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN48436.1 - 5.9e-11 42.1 0.1 1.4e-10 40.9 0.1 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 RLN48436.1 - 0.00026 20.7 0.0 0.00036 20.2 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 RLN48436.1 - 0.00039 20.1 0.0 0.00056 19.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 RLN48436.1 - 0.011 15.6 0.1 0.043 13.7 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 RLN48436.1 - 0.02 15.0 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein LIP PF03583.14 RLN48436.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase Ndr PF03096.14 RLN48436.1 - 0.18 10.5 0.0 0.32 9.7 0.0 1.3 1 0 0 1 1 1 0 Ndr family Abhydrolase_1 PF00561.20 RLN48437.1 - 5.8e-32 111.4 0.0 2.6e-15 56.8 0.0 4.3 2 2 2 4 4 4 3 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN48437.1 - 3.6e-20 73.5 0.0 1.3e-10 42.2 0.1 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN48437.1 - 2e-07 30.6 0.0 0.027 13.8 0.0 3.3 2 2 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 RLN48437.1 - 3.8e-07 30.2 0.0 0.011 15.8 0.0 2.3 2 0 0 2 2 2 2 TAP-like protein EHN PF06441.12 RLN48437.1 - 0.00025 21.4 0.4 0.00077 19.8 0.4 1.9 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Ndr PF03096.14 RLN48437.1 - 0.0026 16.5 0.0 0.13 10.9 0.0 2.2 2 0 0 2 2 2 2 Ndr family DHC_N1 PF08385.12 RLN48438.1 - 4.5e-185 616.5 6.2 4.5e-185 616.5 6.2 1.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 RLN48438.1 - 1e-134 448.6 0.0 4.8e-134 446.4 0.0 2.2 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN48438.1 - 4.4e-110 368.5 1.9 4.4e-110 368.5 1.9 2.5 3 0 0 3 3 1 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RLN48438.1 - 2.4e-81 272.9 0.0 1.8e-80 270.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 TIM PF00121.18 RLN48438.1 - 3.5e-78 262.4 0.1 6.9e-78 261.4 0.1 1.5 1 0 0 1 1 1 1 Triosephosphate isomerase AAA_9 PF12781.7 RLN48438.1 - 2.8e-66 222.8 0.0 5.2e-65 218.6 0.0 2.6 2 0 0 2 2 2 1 ATP-binding dynein motor region Dynein_C PF18199.1 RLN48438.1 - 2.2e-62 211.1 0.0 1.1e-61 208.8 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 RLN48438.1 - 1.3e-45 155.2 0.0 1e-40 139.2 0.0 4.3 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RLN48438.1 - 4.6e-45 153.4 0.0 8.8e-45 152.5 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RLN48438.1 - 2.7e-38 130.7 0.0 4.2e-37 126.9 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 RLN48438.1 - 3.4e-33 115.1 8.5 8e-33 113.9 8.5 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor PT PF04886.12 RLN48438.1 - 7.2e-19 67.0 104.9 1.5e-05 24.5 21.5 5.0 2 2 2 4 4 4 4 PT repeat AAA_5 PF07728.14 RLN48438.1 - 3.7e-18 65.8 0.1 1.5e-06 28.2 0.0 5.8 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 RLN48438.1 - 3.8e-18 65.8 0.0 1.6e-17 63.8 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RLN48438.1 - 1.7e-14 53.8 0.0 6.9e-14 51.9 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 RLN48438.1 - 2.4e-10 41.1 22.0 0.00059 20.2 0.3 7.0 6 1 0 6 6 5 4 AAA ATPase domain AAA PF00004.29 RLN48438.1 - 8.8e-10 39.1 0.8 0.27 11.7 0.0 4.8 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RLN48438.1 - 5.6e-06 26.2 0.3 0.0013 18.5 0.0 3.5 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_18 PF13238.6 RLN48438.1 - 9.2e-06 26.2 1.6 3.1 8.3 0.0 5.7 5 0 0 5 5 4 1 AAA domain AAA_22 PF13401.6 RLN48438.1 - 1.1e-05 25.8 13.8 0.06 13.6 0.0 6.6 7 0 0 7 7 5 2 AAA domain AAA_29 PF13555.6 RLN48438.1 - 1.4e-05 24.7 0.2 0.4 10.5 0.0 3.5 3 0 0 3 3 3 2 P-loop containing region of AAA domain ABC_tran PF00005.27 RLN48438.1 - 6.9e-05 23.4 3.2 0.79 10.2 0.1 4.2 4 0 0 4 4 3 2 ABC transporter RsgA_GTPase PF03193.16 RLN48438.1 - 8.5e-05 22.5 0.2 0.96 9.3 0.0 4.0 4 0 0 4 4 3 2 RsgA GTPase AAA_33 PF13671.6 RLN48438.1 - 0.0009 19.4 1.9 35 4.5 0.1 5.2 5 0 0 5 5 4 0 AAA domain NACHT PF05729.12 RLN48438.1 - 0.00096 19.1 0.3 1.7 8.5 0.0 3.9 3 0 0 3 3 2 1 NACHT domain DUF815 PF05673.13 RLN48438.1 - 0.0012 18.1 0.2 1.4 8.1 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 RLN48438.1 - 0.0026 17.2 0.4 1.7 8.0 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 RLN48438.1 - 0.0036 17.3 3.8 5.3 7.1 0.0 4.5 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 RLN48438.1 - 0.0043 16.8 14.6 0.37 10.5 0.0 5.0 6 0 0 6 6 5 2 AAA domain RNA_helicase PF00910.22 RLN48438.1 - 0.0061 16.9 0.1 23 5.4 0.0 3.7 3 0 0 3 3 3 0 RNA helicase Sigma54_activ_2 PF14532.6 RLN48438.1 - 0.033 14.3 0.7 0.23 11.5 0.0 2.9 3 0 0 3 3 1 0 Sigma-54 interaction domain NB-ARC PF00931.22 RLN48438.1 - 0.043 13.0 0.1 16 4.6 0.0 3.4 3 0 0 3 3 3 0 NB-ARC domain Roc PF08477.13 RLN48438.1 - 0.073 13.3 0.2 14 6.0 0.0 3.3 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 RLN48438.1 - 0.074 13.1 0.1 19 5.4 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 RLN48438.1 - 0.19 11.4 3.1 12 5.5 0.0 4.1 4 0 0 4 4 4 0 AAA domain Cytidylate_kin PF02224.18 RLN48438.1 - 0.2 11.4 1.0 6 6.5 0.1 3.3 3 0 0 3 3 3 0 Cytidylate kinase Zeta_toxin PF06414.12 RLN48438.1 - 0.93 8.7 2.8 10 5.3 0.0 3.4 4 0 0 4 4 3 0 Zeta toxin AAA_23 PF13476.6 RLN48438.1 - 1.5 9.3 0.0 1.5 9.3 0.0 5.1 5 0 0 5 5 4 0 AAA domain AAA_6 PF12774.7 RLN48439.1 - 1.9e-162 539.8 0.1 1.1e-160 534.0 0.0 2.7 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN48439.1 - 1.6e-123 412.7 0.5 1.6e-123 412.7 0.5 3.5 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RLN48439.1 - 1.7e-107 358.6 0.1 9e-107 356.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 RLN48439.1 - 2.2e-101 339.1 0.0 6.5e-99 331.0 0.0 3.3 4 0 0 4 4 4 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 RLN48439.1 - 1.1e-91 305.9 0.6 1.1e-91 305.9 0.6 2.5 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 RLN48439.1 - 1.2e-70 236.7 0.1 2.3e-66 222.8 0.0 3.7 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RLN48439.1 - 1e-47 162.0 0.0 2.9e-47 160.5 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 RLN48439.1 - 3.7e-47 161.0 12.6 7.8e-47 160.0 12.6 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RLN48439.1 - 5.9e-46 155.4 0.0 2.7e-42 143.6 0.0 3.2 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 RLN48439.1 - 9.5e-23 80.7 0.0 3.7e-22 78.8 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RLN48439.1 - 1.6e-18 66.7 0.0 1.5e-17 63.6 0.0 2.7 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 RLN48439.1 - 3.7e-17 62.6 0.0 0.00012 22.1 0.0 6.0 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RLN48439.1 - 7.9e-08 32.9 4.4 0.85 10.0 0.0 6.3 6 1 0 7 7 5 2 AAA ATPase domain AAA_22 PF13401.6 RLN48439.1 - 1.5e-07 31.7 0.0 0.71 10.1 0.0 4.9 5 0 0 5 5 4 2 AAA domain AAA PF00004.29 RLN48439.1 - 1.9e-07 31.6 0.0 0.24 11.8 0.0 4.9 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 RLN48439.1 - 1.2e-06 28.8 0.0 2.5 8.5 0.0 4.7 3 0 0 3 3 3 2 RNA helicase AAA_18 PF13238.6 RLN48439.1 - 2.3e-05 25.0 0.4 0.26 11.8 0.0 4.2 4 0 0 4 4 3 2 AAA domain NACHT PF05729.12 RLN48439.1 - 0.00011 22.1 0.0 0.49 10.3 0.0 3.6 3 0 0 3 3 3 1 NACHT domain AAA_29 PF13555.6 RLN48439.1 - 0.00017 21.2 0.1 0.066 13.0 0.0 3.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain T2SSE PF00437.20 RLN48439.1 - 0.00045 19.4 0.1 0.13 11.3 0.0 3.6 4 0 0 4 4 4 1 Type II/IV secretion system protein ABC_tran PF00005.27 RLN48439.1 - 0.0032 18.0 0.0 1.2 9.6 0.0 4.1 4 0 0 4 4 2 1 ABC transporter TsaE PF02367.17 RLN48439.1 - 0.0046 17.0 0.4 11 6.1 0.0 3.6 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 RLN48439.1 - 0.0082 15.9 0.1 0.33 10.6 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_30 PF13604.6 RLN48439.1 - 0.0098 15.6 0.3 6.2 6.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 RLN48439.1 - 0.013 14.9 0.1 6.3 6.1 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 RLN48439.1 - 0.019 15.1 0.0 3.4 7.8 0.0 3.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 RLN48439.1 - 0.021 14.7 0.1 5.3 6.9 0.0 3.3 3 0 0 3 3 3 0 RsgA GTPase DUF815 PF05673.13 RLN48439.1 - 0.029 13.5 0.1 7.9 5.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Cytidylate_kin PF02224.18 RLN48439.1 - 0.03 14.1 0.0 11 5.7 0.0 3.2 3 0 0 3 3 3 0 Cytidylate kinase AAA_25 PF13481.6 RLN48439.1 - 0.084 12.4 1.2 4.9 6.7 0.0 3.5 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 RLN48439.1 - 0.1 12.8 0.1 2.6 8.3 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 RLN48439.1 - 0.34 10.9 8.4 6.4 6.8 0.0 4.3 4 1 1 5 5 3 0 Helicase HerA, central domain Cupin_4 PF08007.12 RLN48441.1 - 2.6e-60 204.5 0.0 3.4e-60 204.2 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 RLN48441.1 - 1e-06 28.6 0.0 0.00011 22.1 0.0 2.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_1 PF00190.22 RLN48441.1 - 0.024 14.2 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.11 RLN48441.1 - 0.1 12.3 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Cupin domain Pkinase PF00069.25 RLN48443.1 - 1.2e-21 77.3 0.0 2.1e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Bromodomain PF00439.25 RLN48443.1 - 1.1e-12 47.9 0.0 2.1e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Pkinase_Tyr PF07714.17 RLN48443.1 - 3.1e-10 39.8 0.0 7.8e-10 38.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase WCCH PF03716.14 RLN48443.1 - 9.3 6.0 7.5 26 4.6 1.0 2.6 2 0 0 2 2 2 0 WCCH motif Acetyltransf_1 PF00583.25 RLN48444.1 - 2.1e-10 40.8 0.6 2.8e-08 34.0 0.6 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RLN48444.1 - 1.7e-09 37.9 0.1 2.5e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RLN48444.1 - 3.4e-09 36.7 0.9 2.6e-07 30.6 0.9 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN48444.1 - 2.4e-05 24.2 0.5 0.15 12.0 0.0 2.2 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_CG PF14542.6 RLN48444.1 - 0.00011 22.2 0.2 0.00019 21.5 0.2 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 RLN48444.1 - 0.00048 19.7 0.0 0.00053 19.5 0.0 1.1 1 0 0 1 1 1 1 Putative acetyl-transferase PanZ PF12568.8 RLN48444.1 - 0.014 15.1 0.2 0.02 14.6 0.2 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ DIOX_N PF14226.6 RLN48445.1 - 6.6e-12 46.2 0.0 1.3e-11 45.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 RLN48445.1 - 2e-06 28.2 0.0 5.2e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rav1p_C PF12234.8 RLN48446.1 - 1.3e-32 113.0 0.7 5.6e-27 94.4 0.0 2.4 1 1 1 2 2 2 2 RAVE protein 1 C terminal PDZ_6 PF17820.1 RLN48446.1 - 0.046 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 PDZ domain DUF2151 PF10221.9 RLN48446.1 - 0.15 10.6 8.5 0.29 9.7 8.5 1.4 1 0 0 1 1 1 0 Cell cycle and development regulator PDZ PF00595.24 RLN48446.1 - 0.17 12.3 0.1 0.45 10.9 0.1 1.7 1 0 0 1 1 1 0 PDZ domain Pkinase PF00069.25 RLN48447.1 - 9.3e-17 61.3 0.0 3.8e-08 33.0 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain PP2C PF00481.21 RLN48447.1 - 2e-16 60.4 0.1 1.4e-11 44.5 0.0 2.4 2 1 0 2 2 2 2 Protein phosphatase 2C cNMP_binding PF00027.29 RLN48447.1 - 4e-11 42.8 0.0 0.00023 21.2 0.0 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 RLN48447.1 - 4.7e-08 32.6 0.0 0.0051 16.1 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 RLN48447.1 - 0.029 13.7 0.0 1.3 8.3 0.0 2.2 1 1 1 2 2 2 0 Kinase-like PP2C_2 PF13672.6 RLN48447.1 - 0.082 12.5 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein phosphatase 2C EF-hand_1 PF00036.32 RLN48454.1 - 7e-12 44.0 3.2 3.8e-05 22.9 0.7 3.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RLN48454.1 - 1.5e-11 44.5 4.0 2.5e-11 43.8 1.2 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN48454.1 - 1.7e-08 33.7 0.8 0.0021 17.8 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 RLN48454.1 - 2.3e-06 27.3 4.6 0.006 16.4 1.1 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN48454.1 - 1.6e-05 24.2 0.4 0.054 13.0 0.1 3.0 2 0 0 2 2 2 2 EF hand K-box PF01486.17 RLN48454.1 - 0.042 14.0 0.8 0.2 11.9 0.8 2.2 1 0 0 1 1 1 0 K-box region SPC25 PF06703.11 RLN48454.1 - 0.57 10.0 3.0 14 5.5 0.2 3.7 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Peptidase_M14 PF00246.24 RLN48455.1 - 3.7e-11 43.4 0.0 1.3e-10 41.6 0.0 1.8 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 RLN48455.1 - 3.6e-07 30.5 0.0 1.3e-06 28.7 0.0 2.0 1 1 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 RLN48455.1 - 0.0023 17.0 0.4 0.0044 16.1 0.1 1.6 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family Peptidase_M55 PF04951.13 RLN48456.1 - 0.025 14.0 0.3 0.031 13.7 0.3 1.1 1 0 0 1 1 1 0 D-aminopeptidase Cullin PF00888.22 RLN48457.1 - 2.2e-196 654.2 8.2 2.9e-196 653.8 8.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 RLN48457.1 - 9.3e-25 86.5 1.1 9.5e-24 83.2 0.8 2.8 2 0 0 2 2 2 1 Cullin protein neddylation domain TPR_17 PF13431.6 RLN48457.1 - 0.018 15.4 0.2 0.045 14.1 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat GlnD_UR_UTase PF08335.11 RLN48457.1 - 0.072 13.2 2.2 7.8 6.6 0.1 2.6 2 0 0 2 2 2 0 GlnD PII-uridylyltransferase Peptidase_C2 PF00648.21 RLN48461.1 - 7.6e-42 143.3 0.0 2.1e-41 141.9 0.0 1.6 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 RLN48461.1 - 2.2e-20 73.4 0.0 3.4e-06 27.4 0.0 4.6 4 1 0 4 4 4 4 Calpain large subunit, domain III ATP_sub_h PF10775.9 RLN48461.1 - 0.14 12.2 0.1 0.36 10.9 0.1 1.7 1 0 0 1 1 1 0 ATP synthase complex subunit h MIT PF04212.18 RLN48461.1 - 0.24 11.5 9.6 0.1 12.7 6.2 2.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 RLN48461.1 - 0.74 10.1 3.8 1.7 9.0 1.8 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Cytochrom_B561 PF03188.16 RLN48462.1 - 2e-16 60.4 2.4 1.9e-08 34.6 0.3 2.7 1 1 1 2 2 2 2 Eukaryotic cytochrome b561 bZIP_2 PF07716.15 RLN48462.1 - 0.089 12.9 0.3 0.15 12.2 0.3 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Arm PF00514.23 RLN48463.1 - 0.002 18.1 10.7 2.6 8.2 0.3 6.3 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat Mito_carr PF00153.27 RLN48464.1 - 7.3e-38 128.4 0.4 2.5e-18 65.8 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein Kelch_5 PF13854.6 RLN48465.1 - 6.9e-20 70.6 0.0 2.7e-06 27.2 0.0 5.2 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 RLN48465.1 - 1.8e-19 69.5 0.2 9.2e-08 32.0 0.1 5.1 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 RLN48465.1 - 2.1e-18 65.6 3.3 6.9e-09 35.2 0.0 4.3 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 RLN48465.1 - 7e-15 54.3 7.9 7.1e-06 25.8 0.1 5.5 5 1 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 RLN48465.1 - 5e-12 45.6 0.9 7.3e-07 29.3 0.0 4.3 3 1 1 4 4 4 2 Kelch motif Kelch_3 PF13415.6 RLN48465.1 - 5.1e-12 45.8 3.7 0.076 13.3 0.0 6.0 6 1 0 6 6 6 3 Galactose oxidase, central domain RAG2 PF03089.14 RLN48465.1 - 0.029 13.4 0.0 0.055 12.4 0.0 1.4 1 0 0 1 1 1 0 Recombination activating protein 2 Oxidored_FMN PF00724.20 RLN48466.1 - 9.7e-82 275.0 0.0 1.1e-81 274.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 RLN48466.1 - 0.0087 15.5 0.0 9.1 5.6 0.0 3.0 2 1 1 3 3 3 2 Xylose isomerase-like TIM barrel Clathrin-link PF09268.10 RLN48466.1 - 0.16 11.4 0.1 0.16 11.4 0.1 1.6 2 0 0 2 2 2 0 Clathrin, heavy-chain linker GMC_oxred_C PF05199.13 RLN48475.1 - 1.5e-37 129.3 0.2 2.6e-37 128.5 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Abhydrolase_3 PF07859.13 RLN48475.1 - 1.4e-26 93.7 0.0 2.7e-15 56.8 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN48475.1 - 2.2e-08 33.4 0.0 3.4e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase GMC_oxred_N PF00732.19 RLN48475.1 - 2.9e-07 30.2 0.6 4.4e-07 29.6 0.6 1.2 1 0 0 1 1 1 1 GMC oxidoreductase COesterase PF00135.28 RLN48475.1 - 0.021 13.7 0.1 0.041 12.8 0.1 1.3 1 0 0 1 1 1 0 Carboxylesterase family Esterase PF00756.20 RLN48475.1 - 0.098 12.3 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Putative esterase DLH PF01738.18 RLN48475.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family TSP_1 PF00090.19 RLN48482.1 - 1.8e-07 31.2 8.6 0.0033 17.6 0.6 3.2 3 0 0 3 3 3 2 Thrombospondin type 1 domain TSP_1 PF00090.19 RLN48483.1 - 9.4e-24 83.4 69.4 8.6e-06 25.9 0.3 11.1 10 2 0 10 10 10 8 Thrombospondin type 1 domain PTN_MK_C PF01091.18 RLN48483.1 - 8e-08 32.6 44.8 0.29 11.5 0.7 9.7 9 1 1 10 10 10 6 PTN/MK heparin-binding protein family, C-terminal domain zf-CCCH_2 PF14608.6 RLN48484.1 - 0.45 11.1 1.9 0.98 10.0 0.7 2.2 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 RLN48484.1 - 1.1 9.3 4.4 2.2 8.3 4.4 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF4211 PF13926.6 RLN48485.1 - 2e-26 92.8 0.7 2e-26 92.8 0.7 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4211) zf-C3HC4_3 PF13920.6 RLN48485.1 - 5.6e-09 35.7 8.9 5.6e-09 35.7 8.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) YL1 PF05764.13 RLN48485.1 - 0.38 10.9 51.7 0.022 14.9 5.5 3.6 3 0 0 3 3 3 0 YL1 nuclear protein TilS PF09179.11 RLN48485.1 - 1.8 9.1 4.6 27 5.4 0.0 3.4 3 0 0 3 3 3 0 TilS substrate binding domain Pkinase PF00069.25 RLN48486.1 - 7.7e-54 182.8 0.0 8.9e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN48486.1 - 9.7e-43 146.3 0.0 1.2e-42 146.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN48486.1 - 7.8e-05 21.6 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 RLN48486.1 - 0.00035 19.6 0.9 0.0014 17.7 0.9 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RLN48486.1 - 0.001 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN48486.1 - 0.0057 16.6 0.0 0.009 15.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN48486.1 - 0.097 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Closter_coat PF01785.17 RLN48486.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Closterovirus coat protein PB1 PF00564.24 RLN48488.1 - 3.5e-08 33.3 0.0 2.5e-07 30.5 0.0 2.5 4 0 0 4 4 4 1 PB1 domain CUE PF02845.16 RLN48488.1 - 0.00024 20.7 0.1 0.00049 19.8 0.1 1.5 1 0 0 1 1 1 1 CUE domain B56 PF01603.20 RLN48488.1 - 0.0065 15.5 0.7 0.0095 14.9 0.7 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Apolipoprotein PF01442.18 RLN48488.1 - 0.013 15.4 5.9 0.023 14.6 5.9 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain SGTA_dimer PF16546.5 RLN48488.1 - 0.031 14.0 0.2 0.17 11.7 0.1 2.2 1 1 1 2 2 2 0 Homodimerisation domain of SGTA Toxin_trans PF07952.12 RLN48488.1 - 0.044 12.9 0.1 0.055 12.5 0.1 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain DUF2524 PF10732.9 RLN48488.1 - 0.048 14.0 3.8 0.2 12.0 3.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2524) Flagellin_N PF00669.20 RLN48488.1 - 0.17 12.0 4.2 9.9 6.3 0.0 2.4 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region IL12 PF03039.14 RLN48488.1 - 0.19 11.0 0.8 12 5.2 0.1 2.2 1 1 1 2 2 2 0 Interleukin-12 alpha subunit HisKA_3 PF07730.13 RLN48488.1 - 0.33 11.5 3.2 6.9 7.3 3.2 2.6 1 1 0 1 1 1 0 Histidine kinase DUF148 PF02520.17 RLN48488.1 - 0.36 11.0 6.1 0.49 10.5 4.4 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF148 Dak2 PF02734.17 RLN48488.1 - 1.1 9.1 5.9 0.47 10.3 2.5 1.9 1 1 0 2 2 2 0 DAK2 domain DUF883 PF05957.13 RLN48488.1 - 2 9.1 6.4 1.8 9.2 4.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) PALP PF00291.25 RLN48489.1 - 1.2e-65 221.8 3.7 2.1e-65 221.1 3.7 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CRAL_TRIO PF00650.20 RLN48489.1 - 8.9e-34 116.5 0.0 1.4e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain ACT PF01842.25 RLN48489.1 - 0.0022 17.7 0.0 0.0056 16.4 0.0 1.7 1 0 0 1 1 1 1 ACT domain PH PF00169.29 RLN48489.1 - 0.021 15.3 0.4 0.39 11.2 0.1 2.4 1 1 1 2 2 2 0 PH domain CRAL_TRIO_2 PF13716.6 RLN48489.1 - 0.032 14.4 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain PI3Ka PF00613.20 RLN48490.1 - 2.9e-44 150.7 0.1 5.2e-44 149.9 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 RLN48490.1 - 1.9e-43 149.1 0.0 4e-42 144.8 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PH PF00169.29 RLN48490.1 - 2.6e-30 105.0 3.2 5.4e-15 55.8 0.4 3.1 3 0 0 3 3 3 2 PH domain PH_11 PF15413.6 RLN48490.1 - 3.9e-11 43.3 1.0 1e-05 25.9 0.0 2.9 2 0 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 RLN48490.1 - 3.1e-08 33.8 7.5 0.00033 20.9 1.2 4.3 4 1 0 4 4 4 2 Pleckstrin homology domain PI3K_C2 PF00792.24 RLN48490.1 - 8.7e-06 25.7 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 RLN48490.1 - 1.7e-05 24.9 0.1 4e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain DUF4135 PF13575.6 RLN48490.1 - 0.0062 15.9 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) CRM1_C PF08767.11 RLN48490.1 - 0.066 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 CRM1 C terminal DUF2833 PF11090.8 RLN48490.1 - 0.15 12.5 0.2 0.91 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) WD40 PF00400.32 RLN48491.1 - 2.8e-17 62.7 15.2 9.7e-06 26.2 0.1 10.1 11 0 0 11 11 11 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN48491.1 - 2.8e-07 30.7 0.0 0.23 11.8 0.0 6.1 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain GCP_N_terminal PF17681.1 RLN48491.1 - 3.1e-06 27.0 0.0 7.2e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal CENP-F_leu_zip PF10473.9 RLN48491.1 - 0.00086 19.3 12.4 0.00086 19.3 12.4 6.5 3 2 3 6 6 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 RLN48491.1 - 3 7.8 17.0 0.049 13.6 6.8 3.1 2 1 0 2 2 2 0 Laminin Domain II tRNA-synt_1 PF00133.22 RLN48492.1 - 3.8e-26 91.5 0.0 1.7e-25 89.4 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 RLN48492.1 - 1.8e-10 41.0 0.0 3.7e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 RLN48492.1 - 2.7e-08 33.0 0.0 5.1e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 RLN48492.1 - 3e-08 33.4 0.0 6.5e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain eIF2_C PF09173.11 RLN48493.1 - 6.2e-37 125.7 0.8 1.7e-36 124.3 0.8 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 RLN48493.1 - 3e-23 82.4 1.4 1.7e-22 79.9 1.4 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 RLN48493.1 - 5.4e-14 52.3 0.8 5.4e-13 49.1 0.8 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RLN48493.1 - 0.0025 17.9 0.0 0.0075 16.3 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RLN48493.1 - 0.014 15.3 1.0 0.25 11.2 0.2 2.4 2 0 0 2 2 2 0 RsgA GTPase DUF1098 PF06497.11 RLN48493.1 - 0.11 13.0 0.3 0.35 11.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) Abhydrolase_1 PF00561.20 RLN48518.1 - 2e-27 96.5 0.0 3.9e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold TPR_2 PF07719.17 RLN48518.1 - 8.6e-24 81.7 19.6 0.0022 18.0 0.0 10.2 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 RLN48518.1 - 7.5e-22 75.7 13.7 0.00068 19.7 0.0 9.4 11 0 0 11 11 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 RLN48518.1 - 5.2e-21 73.5 9.0 0.00014 21.6 0.0 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 RLN48518.1 - 2.4e-19 68.3 18.8 0.022 15.5 0.0 11.0 5 2 5 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 RLN48518.1 - 2.9e-19 69.1 19.0 0.00067 19.9 0.1 9.4 5 4 1 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 RLN48518.1 - 3.1e-15 55.0 13.3 0.0028 17.6 0.1 8.9 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 RLN48518.1 - 1.2e-14 54.7 11.0 0.0025 18.4 0.0 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 RLN48518.1 - 4.4e-12 46.3 20.4 0.00015 22.2 0.0 8.3 5 1 3 9 9 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN48518.1 - 1.7e-11 44.2 14.7 3.4e-07 30.4 0.8 6.2 7 0 0 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 RLN48518.1 - 3.3e-11 43.1 17.8 1.2 9.9 0.1 9.6 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN48518.1 - 6.7e-10 38.5 1.4 0.22 11.2 0.0 7.5 6 2 2 8 8 8 1 TPR repeat TPR_17 PF13431.6 RLN48518.1 - 1.1e-09 38.0 1.5 0.023 15.1 0.1 7.2 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN48518.1 - 2.4e-06 27.6 9.4 0.22 11.7 0.0 5.5 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 RLN48518.1 - 2.9e-06 27.5 6.6 0.52 10.7 0.2 6.5 5 1 1 6 6 6 2 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 RLN48518.1 - 3.8e-06 27.7 1.5 0.00055 20.6 0.0 3.1 3 0 0 3 3 3 1 Alpha/beta hydrolase family TPR_15 PF13429.6 RLN48518.1 - 0.00033 20.0 7.6 0.55 9.4 5.2 4.0 2 1 0 2 2 2 2 Tetratricopeptide repeat Hydrolase_4 PF12146.8 RLN48518.1 - 0.0074 15.6 0.0 0.022 14.1 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 ChAPs PF09295.10 RLN48518.1 - 0.0088 15.1 2.2 0.75 8.7 0.1 3.4 2 1 2 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) Esterase PF00756.20 RLN48518.1 - 0.029 14.0 0.0 0.077 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative esterase TPR_10 PF13374.6 RLN48518.1 - 0.04 13.8 14.1 12 5.9 0.0 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat Ribonuc_red_lgN PF00317.21 RLN48518.1 - 0.076 13.0 1.8 0.36 10.9 0.1 2.7 2 1 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain SDA1 PF05285.12 RLN48518.1 - 2.2 7.6 20.1 0.93 8.9 1.7 2.2 2 0 0 2 2 2 0 SDA1 MIT PF04212.18 RLN48518.1 - 3.5 7.8 5.9 16 5.7 0.0 4.6 6 0 0 6 6 4 0 MIT (microtubule interacting and transport) domain Lipase_3 PF01764.25 RLN48519.1 - 2.6e-19 69.5 0.0 7.1e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) FYVE PF01363.21 RLN48519.1 - 7.8e-18 64.4 21.5 6e-12 45.5 9.9 2.5 2 0 0 2 2 2 2 FYVE zinc finger Rpr2 PF04032.16 RLN48519.1 - 0.017 15.4 6.9 0.23 11.8 3.2 3.4 3 0 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain MerR PF00376.23 RLN48519.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 MerR family regulatory protein FYVE_2 PF02318.16 RLN48519.1 - 2.1 8.6 14.6 7.8 6.7 5.9 3.0 2 0 0 2 2 2 0 FYVE-type zinc finger RRN3 PF05327.11 RLN48520.1 - 9.2 4.7 10.1 12 4.3 10.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Presenilin PF01080.17 RLN48520.1 - 9.6 4.8 13.2 14 4.3 13.2 1.4 1 0 0 1 1 1 0 Presenilin DLIC PF05783.11 RLN48521.1 - 1.6e-08 33.8 0.2 0.00037 19.5 0.0 2.0 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 RLN48521.1 - 0.011 16.1 0.1 0.034 14.5 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 RLN48521.1 - 0.087 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Trypsin_2 PF13365.6 RLN48522.1 - 3.1e-25 89.8 2.6 6.1e-21 75.9 0.1 2.4 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_1 PF12812.7 RLN48522.1 - 4.1e-16 58.7 0.0 8.1e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 PDZ-like domain PDZ_2 PF13180.6 RLN48522.1 - 2.2e-05 24.7 0.0 0.0085 16.4 0.0 2.6 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 RLN48522.1 - 7.8e-05 22.4 0.1 0.0028 17.5 0.0 2.7 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 RLN48522.1 - 0.00024 21.4 0.0 0.0021 18.4 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 RLN48522.1 - 0.0011 17.7 0.4 0.0011 17.7 0.4 1.5 2 0 0 2 2 2 1 Peptidase S46 Trypsin PF00089.26 RLN48522.1 - 0.0036 17.1 0.0 0.0063 16.3 0.0 1.4 1 0 0 1 1 1 1 Trypsin Peptidase_S7 PF00949.21 RLN48522.1 - 0.078 12.8 0.4 0.16 11.8 0.4 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.16 RLN48522.1 - 0.093 12.3 0.4 0.14 11.7 0.4 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_M28 PF04389.17 RLN48535.1 - 1.1e-16 61.1 0.0 1.8e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 RLN48535.1 - 2.2e-10 40.4 0.0 5.9e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 PA domain TFR_dimer PF04253.15 RLN48536.1 - 1.4e-28 99.4 0.0 2.8e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 RLN48536.1 - 5.4e-18 65.4 0.0 1.2e-17 64.3 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 RLN48536.1 - 4.4e-05 23.3 0.1 9.4e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 SUKH-4 PF14435.6 RLN48536.1 - 0.013 15.6 2.1 0.046 13.8 1.3 2.2 2 0 0 2 2 2 0 SUKH-4 immunity protein WXG100 PF06013.12 RLN48536.1 - 0.013 15.7 0.3 2 8.7 0.1 3.2 2 1 1 3 3 3 0 Proteins of 100 residues with WXG CAS_C PF12026.8 RLN48536.1 - 0.18 11.9 0.3 0.3 11.1 0.3 1.3 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain PPR_long PF17177.4 RLN48537.1 - 0.00012 21.5 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP Pkinase PF00069.25 RLN48556.1 - 3.9e-76 255.9 0.0 4.7e-76 255.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN48556.1 - 2.8e-40 138.2 0.0 3.5e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN48556.1 - 3.4e-06 26.6 0.0 5.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN48556.1 - 1.9e-05 24.1 0.0 6.4e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RLN48556.1 - 6.7e-05 21.8 0.0 9.9e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN48556.1 - 0.00059 19.8 0.0 0.0026 17.7 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 RLN48556.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ARL2_Bind_BART PF11527.8 RLN48558.1 - 2e-08 34.3 0.8 2.4e-08 34.1 0.8 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART MFS_1 PF07690.16 RLN48560.1 - 5.7e-15 55.1 50.2 2.5e-09 36.5 17.4 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RLN48560.1 - 1.8e-10 40.0 17.3 1.8e-10 40.0 17.3 2.3 2 0 0 2 2 2 1 MFS/sugar transport protein BCL_N PF04714.13 RLN48561.1 - 0.15 12.1 0.3 0.26 11.4 0.3 1.3 1 0 0 1 1 1 0 BCL7, N-terminal conserver region Pneumo_att_G PF05539.11 RLN48561.1 - 4.2 6.9 14.5 5.4 6.5 14.5 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G SOG2 PF10428.9 RLN48561.1 - 8.6 5.4 13.1 9.8 5.2 13.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Pkinase_Tyr PF07714.17 RLN48574.1 - 6.6e-08 32.1 0.0 8.7e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN48574.1 - 9e-05 22.0 0.0 0.00023 20.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain PH PF00169.29 RLN48574.1 - 0.00011 22.7 0.8 0.00022 21.7 0.8 1.6 1 0 0 1 1 1 1 PH domain SAM_1 PF00536.30 RLN48574.1 - 0.0015 19.0 0.0 0.0032 17.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CAP PF00188.26 RLN48587.1 - 1.2e-09 39.0 0.2 1.5e-09 38.7 0.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family BRCT PF00533.26 RLN48588.1 - 5.4e-05 23.5 0.0 0.0006 20.1 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 RLN48588.1 - 0.00026 21.3 0.2 1.8 9.0 0.2 3.1 2 1 1 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 RLN48588.1 - 0.0035 17.2 0.0 0.0086 15.9 0.0 1.7 1 1 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 RLN48589.1 - 0.05 13.6 0.1 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 twin BRCT domain Peptidase_C48 PF02902.19 RLN48597.1 - 3.7e-09 36.7 0.0 6.2e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain cNMP_binding PF00027.29 RLN48598.1 - 3.3e-08 33.5 0.0 0.0083 16.2 0.0 2.8 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain TetR_C_28 PF17937.1 RLN48598.1 - 0.45 11.0 4.6 0.32 11.5 0.7 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Peptidase_S9_N PF02897.15 RLN48599.1 - 6.6e-110 367.7 0.1 9.6e-110 367.2 0.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 RLN48599.1 - 1.2e-59 201.4 0.0 2.3e-59 200.4 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 RLN48599.1 - 0.051 13.5 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DIX PF00778.17 RLN48599.1 - 0.096 12.5 0.0 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 DIX domain PLDc_2 PF13091.6 RLN48605.1 - 4.4e-09 36.3 0.0 6.9e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.22 RLN48605.1 - 2.1e-05 24.5 0.3 2.1e-05 24.5 0.3 1.7 2 0 0 2 2 2 1 Phospholipase D Active site motif PLDc PF00614.22 RLN48606.1 - 0.0045 17.1 1.1 0.011 15.9 0.1 2.3 2 1 0 2 2 2 1 Phospholipase D Active site motif Glycos_transf_1 PF00534.20 RLN48607.1 - 0.098 12.2 0.0 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 RLN48608.1 - 0.00064 19.3 0.0 0.0017 17.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RLN48608.1 - 0.014 15.8 0.0 0.068 13.6 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferases group 1 Cation_ATPase_C PF00689.21 RLN48609.1 - 1.9e-16 60.3 3.7 2.3e-16 60.0 3.7 1.0 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus BLACT_WH PF17778.1 RLN48609.1 - 3.8 7.6 4.6 1.2 9.2 0.2 2.2 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain Metallophos PF00149.28 RLN48620.1 - 7.3e-19 69.1 1.2 1.3e-18 68.3 1.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 RLN48620.1 - 5.5e-18 65.3 6.7 5.5e-18 65.3 6.7 2.5 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 RLN48620.1 - 1.6e-15 57.7 0.1 5.9e-15 55.9 0.0 2.1 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C DUF2369 PF10179.9 RLN48620.1 - 0.19 12.2 1.6 0.42 11.0 1.6 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) Glycos_transf_3 PF00591.21 RLN48621.1 - 9.7e-83 277.6 0.1 1.7e-82 276.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 RLN48621.1 - 3.9e-14 52.2 1.4 9.6e-14 51.0 1.4 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain AZUL PF16558.5 RLN48621.1 - 9.2e-14 51.4 4.1 2.1e-13 50.3 4.1 1.7 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Attacin_N PF03768.15 RLN48621.1 - 0.013 15.6 2.3 1.8 8.7 0.8 3.0 2 0 0 2 2 2 0 Attacin, N-terminal region Dynamin_N PF00350.23 RLN48622.1 - 1.8e-10 41.1 0.0 5.1e-06 26.6 0.0 2.6 2 1 0 3 3 3 2 Dynamin family MMR_HSR1 PF01926.23 RLN48622.1 - 2.4e-05 24.4 0.0 7e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF5600 PF18150.1 RLN48622.1 - 0.049 14.2 0.1 0.9 10.2 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5600) FeoB_N PF02421.18 RLN48622.1 - 0.051 13.1 0.0 7.9 6.0 0.0 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RLN48622.1 - 0.064 13.2 0.0 0.87 9.5 0.0 2.5 3 0 0 3 3 3 0 RsgA GTPase AAA_18 PF13238.6 RLN48622.1 - 0.094 13.3 0.0 16 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 RLN48622.1 - 0.23 10.6 0.0 3.8 6.6 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit BUD22 PF09073.10 RLN48623.1 - 3.5e-13 49.7 52.9 3.6e-13 49.7 32.8 3.5 1 1 0 2 2 2 2 BUD22 TPH PF13868.6 RLN48624.1 - 2e-38 131.8 108.4 2e-38 131.8 108.4 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain ubiquitin PF00240.23 RLN48625.1 - 2.1e-05 24.2 0.0 4.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 RLN48625.1 - 0.03 14.4 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CCDC14 PF15254.6 RLN48625.1 - 0.22 10.2 9.1 0.28 9.8 9.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 DENN PF02141.21 RLN48626.1 - 2.7e-08 34.0 0.2 5.9e-08 32.9 0.2 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain Med3 PF11593.8 RLN48626.1 - 0.1 11.8 2.9 0.31 10.2 2.9 1.8 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PyrI_C PF02748.15 RLN48627.1 - 0.025 14.5 0.2 1.1 9.2 0.1 2.6 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain SUIM_assoc PF16619.5 RLN48627.1 - 0.25 11.4 2.5 0.27 11.3 0.1 2.3 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Med26 PF08711.11 RLN48628.1 - 0.01 15.8 1.4 0.036 14.1 0.5 2.3 2 0 0 2 2 2 0 TFIIS helical bundle-like domain DUF61 PF01886.16 RLN48629.1 - 0.14 12.2 0.1 0.38 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF61 Pkinase PF00069.25 RLN48630.1 - 2e-38 132.3 0.0 2.6e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN48630.1 - 4.8e-17 62.1 0.0 6.6e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN48630.1 - 1.9e-08 34.5 1.4 7.1e-08 32.7 1.4 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN48630.1 - 6.5e-06 25.7 0.1 1.1e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RLN48630.1 - 0.0052 16.4 0.0 0.0077 15.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 RLN48630.1 - 0.0057 16.3 0.0 0.017 14.7 0.0 1.7 2 0 0 2 2 2 1 RIO1 family His_Phos_1 PF00300.22 RLN48631.1 - 1.7e-34 119.2 0.0 2.4e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glycos_transf_4 PF00953.21 RLN48631.1 - 2.4e-33 115.4 7.7 2.4e-33 115.4 7.7 2.9 3 0 0 3 3 3 1 Glycosyl transferase family 4 Lectin_legB PF00139.19 RLN48631.1 - 0.052 13.1 0.1 0.087 12.3 0.1 1.2 1 0 0 1 1 1 0 Legume lectin domain DUF647 PF04884.14 RLN48632.1 - 6.8e-90 300.9 1.6 9e-90 300.5 1.6 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Mntp PF02659.15 RLN48632.1 - 0.26 11.0 1.2 0.96 9.2 0.1 2.2 1 1 1 2 2 2 0 Putative manganese efflux pump DHHC PF01529.20 RLN48633.1 - 4.4e-32 111.0 5.5 4.4e-32 111.0 5.5 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 RLN48633.1 - 1.4e-14 54.5 1.1 7.9e-06 26.4 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN48633.1 - 3.5e-13 49.8 7.1 6.7e-05 23.4 0.8 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN48633.1 - 2.4e-10 39.7 4.3 0.2 12.3 0.0 6.4 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 RLN48633.1 - 2.2e-08 34.2 4.6 0.005 17.1 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN48633.1 - 1.4e-06 28.5 0.7 0.36 11.4 0.1 4.3 4 0 0 4 4 4 2 Ankyrin repeat Fer2 PF00111.27 RLN48633.1 - 0.095 12.7 0.8 0.33 10.9 0.8 1.9 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain IGFBP PF00219.18 RLN48633.1 - 0.49 11.1 5.3 0.9 10.2 5.3 1.3 1 0 0 1 1 1 0 Insulin-like growth factor binding protein EF-hand_1 PF00036.32 RLN48650.1 - 9.5e-149 472.3 61.2 1.1e-05 24.6 0.0 26.8 28 0 0 28 28 28 24 EF hand EF-hand_7 PF13499.6 RLN48650.1 - 2e-132 431.8 60.0 2.5e-13 50.2 0.0 18.2 16 3 1 17 17 17 17 EF-hand domain pair EF-hand_6 PF13405.6 RLN48650.1 - 4.3e-129 409.6 60.6 0.00011 21.9 0.1 27.1 26 0 0 26 26 26 24 EF-hand domain EF-hand_5 PF13202.6 RLN48650.1 - 9.5e-106 341.1 80.9 5e-05 22.6 0.0 26.7 27 0 0 27 27 27 23 EF hand EF-hand_8 PF13833.6 RLN48650.1 - 7.8e-57 189.0 82.6 0.0017 18.2 0.1 26.0 20 5 6 27 27 26 19 EF-hand domain pair EF-hand_2 PF09068.11 RLN48650.1 - 9.4e-18 64.5 0.1 0.11 12.6 0.0 10.8 9 4 0 10 10 10 4 EF hand EF-hand_9 PF14658.6 RLN48650.1 - 1.4e-17 63.7 18.0 0.02 15.2 0.0 12.8 12 3 2 14 14 14 4 EF-hand domain EF-hand_4 PF12763.7 RLN48650.1 - 4.5e-14 52.3 51.5 0.72 9.8 0.0 20.4 10 8 12 23 23 23 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RLN48650.1 - 6.4e-10 39.3 24.3 0.63 10.4 0.2 15.3 17 4 0 17 17 16 1 Secreted protein acidic and rich in cysteine Ca binding region FANCM-MHF_bd PF16783.5 RLN48650.1 - 2.8e-07 30.6 6.8 1.7 8.8 0.0 7.7 8 0 0 8 8 8 1 FANCM to MHF binding domain Dockerin_1 PF00404.18 RLN48650.1 - 1.2e-05 25.3 19.8 27 5.0 0.0 12.8 13 4 2 15 15 13 0 Dockerin type I domain DUF1707 PF08044.11 RLN48650.1 - 1.3e-05 25.2 0.5 24 5.1 0.0 9.8 12 0 0 12 12 10 0 Domain of unknown function (DUF1707) DUF4197 PF13852.6 RLN48650.1 - 0.0055 16.4 0.1 0.11 12.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4197) LXG PF04740.12 RLN48650.1 - 0.17 11.6 2.8 1.2e+02 2.2 0.1 5.1 5 0 0 5 5 5 0 LXG domain of WXG superfamily EF-hand_14 PF17959.1 RLN48650.1 - 0.52 10.7 8.6 1e+02 3.4 0.0 7.2 8 0 0 8 8 8 0 EF-hand domain EF-hand_10 PF14788.6 RLN48650.1 - 1.8 8.5 21.8 3.6 7.5 0.1 8.8 11 0 0 11 11 10 0 EF hand PQ-loop PF04193.14 RLN48651.1 - 8.2e-10 38.3 1.3 1.3e-09 37.7 1.3 1.4 1 0 0 1 1 1 1 PQ loop repeat MtN3_slv PF03083.16 RLN48651.1 - 0.00025 21.0 1.1 0.0003 20.7 1.1 1.1 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange TMEM101 PF15111.6 RLN48651.1 - 0.031 13.8 0.1 0.037 13.6 0.1 1.2 1 0 0 1 1 1 0 TMEM101 protein family Peptidase_M16 PF00675.20 RLN48654.1 - 2.2e-34 118.6 0.1 3.1e-34 118.1 0.1 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Herpes_TK PF00693.18 RLN48655.1 - 0.038 13.2 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus Na_Ca_ex PF01699.24 RLN48656.1 - 4.6e-15 55.9 24.6 2.2e-11 43.9 12.1 3.1 3 0 0 3 3 3 3 Sodium/calcium exchanger protein EF-hand_7 PF13499.6 RLN48656.1 - 4.6e-11 43.0 1.4 1.3e-10 41.6 1.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN48656.1 - 1.8e-09 36.5 1.4 0.00029 20.2 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN48656.1 - 6.2e-08 32.0 0.4 0.0023 17.7 0.3 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RLN48656.1 - 0.00017 20.9 2.0 0.022 14.3 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 RLN48656.1 - 0.11 12.4 0.4 0.24 11.3 0.4 1.6 1 0 0 1 1 1 0 EF-hand domain pair DUF2569 PF10754.9 RLN48656.1 - 6 7.3 8.8 13 6.2 0.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2569) PIH1 PF08190.12 RLN48665.1 - 3.9e-11 42.7 0.0 7.9e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 PIH1 N-terminal domain Ribosomal_L21e PF01157.18 RLN48666.1 - 1.8e-05 24.5 2.8 1.8e-05 24.5 2.8 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e Ala_racemase_N PF01168.20 RLN48668.1 - 2.3e-21 76.5 0.7 4.3e-21 75.6 0.7 1.4 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain FYVE PF01363.21 RLN48669.1 - 0.0023 18.1 14.9 0.0046 17.1 14.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger zf-C2HE PF16278.5 RLN48669.1 - 0.015 15.8 0.2 0.075 13.5 0.1 2.2 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger ROS_MUCR PF05443.11 RLN48669.1 - 0.068 13.2 0.3 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein C1_1 PF00130.22 RLN48669.1 - 0.46 10.4 8.2 0.96 9.4 8.2 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 RLN48669.1 - 0.48 10.6 12.6 0.75 10.0 6.6 2.6 2 1 0 2 2 2 0 FYVE-type zinc finger Spt5_N PF11942.8 RLN48669.1 - 1.2 10.1 10.7 0.11 13.5 5.0 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Zn-ribbon_8 PF09723.10 RLN48669.1 - 1.4 9.1 7.3 3.4 7.9 7.3 1.7 1 0 0 1 1 1 0 Zinc ribbon domain AAA_6 PF12774.7 RLN48678.1 - 1.2e-129 432.0 0.1 2.8e-128 427.5 0.0 3.3 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN48678.1 - 9e-117 390.5 11.4 9e-117 390.5 11.4 3.7 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 RLN48678.1 - 1.7e-101 340.6 4.8 1.7e-101 340.6 4.8 4.0 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 RLN48678.1 - 1.7e-73 246.4 10.1 1.9e-73 246.3 0.1 4.5 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 RLN48678.1 - 2.7e-69 233.4 0.2 1e-67 228.2 0.1 2.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 RLN48678.1 - 7.3e-41 139.7 0.0 1.3e-33 116.1 0.0 4.8 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_C PF18199.1 RLN48678.1 - 1.1e-40 139.8 0.0 5e-40 137.6 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain MT PF12777.7 RLN48678.1 - 1.4e-34 119.6 10.8 1.4e-34 119.6 10.8 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 RLN48678.1 - 7.8e-33 113.6 0.0 2.3e-32 112.1 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RLN48678.1 - 2.7e-30 104.9 0.0 4.8e-29 100.9 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 RLN48678.1 - 2.3e-29 102.1 0.0 3.6e-11 43.2 0.0 6.1 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 RLN48678.1 - 9.5e-22 77.5 1.1 1.7e-20 73.4 0.0 3.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 RLN48678.1 - 6.7e-13 49.2 0.0 0.0076 16.7 0.0 5.2 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN48678.1 - 1.4e-12 48.0 0.0 0.0053 17.0 0.0 5.9 5 0 0 5 5 5 2 AAA domain AAA_16 PF13191.6 RLN48678.1 - 1.7e-11 44.8 0.2 0.96 9.8 0.0 7.0 5 0 0 5 5 5 3 AAA ATPase domain AAA_18 PF13238.6 RLN48678.1 - 5.5e-09 36.7 0.1 1.1 9.9 0.0 5.6 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.6 RLN48678.1 - 1e-07 32.2 1.4 0.51 10.5 0.0 5.9 5 0 0 5 5 5 2 AAA domain T2SSE PF00437.20 RLN48678.1 - 6e-06 25.5 0.0 0.09 11.8 0.0 4.0 3 0 0 3 3 3 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 RLN48678.1 - 6.5e-05 22.4 2.2 0.54 9.6 0.0 4.4 5 0 0 5 5 4 1 FtsK/SpoIIIE family AAA_29 PF13555.6 RLN48678.1 - 0.00039 20.1 0.1 1.3 8.8 0.0 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain ABC_tran PF00005.27 RLN48678.1 - 0.0004 20.9 6.8 1.8 9.1 0.0 6.0 6 0 0 6 6 5 1 ABC transporter Mg_chelatase PF01078.21 RLN48678.1 - 0.00047 19.6 2.0 0.35 10.2 0.0 3.8 4 0 0 4 4 3 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 RLN48678.1 - 0.00073 19.9 0.3 0.24 11.7 0.0 4.4 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 RLN48678.1 - 0.00094 19.0 1.7 18 5.0 0.0 4.9 5 0 0 5 5 5 0 AAA domain AAA_lid_1 PF17857.1 RLN48678.1 - 0.0025 18.0 0.1 0.012 15.8 0.1 2.3 1 0 0 1 1 1 1 AAA+ lid domain AAA_25 PF13481.6 RLN48678.1 - 0.0032 17.1 1.4 0.12 11.9 0.0 4.0 4 0 0 4 4 4 1 AAA domain Sigma54_activ_2 PF14532.6 RLN48678.1 - 0.0074 16.4 0.2 9.4 6.3 0.0 4.8 4 0 0 4 4 4 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 RLN48678.1 - 0.0096 15.6 0.0 6.7 6.4 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.22 RLN48678.1 - 0.012 16.0 0.1 75 3.8 0.0 4.7 4 0 0 4 4 4 0 RNA helicase AAA_24 PF13479.6 RLN48678.1 - 0.013 15.2 2.0 49 3.6 0.0 5.5 6 0 0 6 6 5 0 AAA domain RuvB_N PF05496.12 RLN48678.1 - 0.014 15.1 0.0 0.36 10.6 0.0 2.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_7 PF17867.1 RLN48678.1 - 0.037 14.2 0.0 0.34 11.1 0.0 2.9 1 0 0 1 1 1 0 Midasin AAA lid domain NACHT PF05729.12 RLN48678.1 - 0.045 13.7 2.1 25 4.8 0.0 4.5 4 0 0 4 4 4 0 NACHT domain Rad17 PF03215.15 RLN48678.1 - 0.058 13.3 0.2 17 5.3 0.0 4.3 4 0 0 4 4 4 0 Rad17 P-loop domain IstB_IS21 PF01695.17 RLN48678.1 - 0.59 9.8 8.2 1.1 8.9 0.0 4.7 6 0 0 6 6 6 0 IstB-like ATP binding protein LETM1 PF07766.13 RLN48679.1 - 1.7e-97 325.9 3.5 4.2e-97 324.7 3.5 1.7 1 0 0 1 1 1 1 LETM1-like protein EF-hand_8 PF13833.6 RLN48679.1 - 2.1e-05 24.3 0.4 6.4e-05 22.7 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN48679.1 - 0.00014 21.2 2.9 0.016 14.7 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 RLN48679.1 - 0.0012 18.2 3.1 0.015 14.8 0.1 3.4 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.6 RLN48679.1 - 0.0014 19.0 1.8 0.0055 17.1 0.5 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN48679.1 - 0.0083 16.0 1.2 0.12 12.4 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain Ntox27 PF15531.6 RLN48679.1 - 0.012 15.5 0.1 0.04 13.8 0.1 1.8 1 0 0 1 1 1 0 Bacterial toxin 27 PHP PF02811.19 RLN48680.1 - 1.7e-07 31.7 0.0 2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 PHP domain BTB PF00651.31 RLN48681.1 - 1.7e-12 47.5 0.2 4.6e-10 39.7 0.0 2.7 1 1 2 3 3 3 1 BTB/POZ domain Kelch_5 PF13854.6 RLN48681.1 - 0.00018 21.4 0.3 0.00035 20.5 0.3 1.4 1 0 0 1 1 1 1 Kelch motif BACK PF07707.15 RLN48681.1 - 0.00035 20.6 0.4 0.00084 19.4 0.1 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 RLN48681.1 - 0.0026 17.6 0.1 0.0054 16.7 0.1 1.5 1 0 0 1 1 1 1 Kelch motif Kelch_1 PF01344.25 RLN48681.1 - 0.0054 16.3 0.8 0.015 14.9 0.1 1.9 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.6 RLN48681.1 - 0.012 15.9 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 Kelch motif Kelch_4 PF13418.6 RLN48681.1 - 0.059 13.4 0.2 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 Galactose oxidase, central domain Histone PF00125.24 RLN48682.1 - 3.8e-19 69.3 0.0 5.4e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 RLN48682.1 - 3.3e-13 49.1 0.2 6.1e-13 48.3 0.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 RLN48682.1 - 0.00046 20.4 0.0 0.00063 20.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TP_methylase PF00590.20 RLN48688.1 - 0.0068 16.4 0.0 0.0081 16.1 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Dickkopf_N PF04706.12 RLN48689.1 - 0.099 13.1 36.4 0.97 10.0 1.2 7.4 6 2 2 8 8 8 0 Dickkopf N-terminal cysteine-rich region Lustrin_cystein PF14625.6 RLN48689.1 - 5 7.6 47.8 4.9 7.6 1.2 7.6 6 1 1 7 7 7 0 Lustrin, cysteine-rich repeated domain Coq4 PF05019.13 RLN48694.1 - 1.1e-89 299.6 0.0 1.2e-89 299.4 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 T2SSG PF08334.11 RLN48694.1 - 0.056 13.5 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G Glyco_hydro_3 PF00933.21 RLN48695.1 - 3e-48 164.8 0.2 3.3e-48 164.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain DnaJ PF00226.31 RLN48696.1 - 4.6e-22 77.9 0.2 5.4e-22 77.7 0.2 1.1 1 0 0 1 1 1 1 DnaJ domain HD_4 PF13328.6 RLN48696.1 - 0.047 13.4 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 HD domain FYVE PF01363.21 RLN48713.1 - 2.2e-13 50.1 17.5 4.7e-13 49.1 17.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger Arf PF00025.21 RLN48714.1 - 2.1e-19 69.6 0.0 1.4e-14 53.9 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_22 PF13401.6 RLN48714.1 - 0.0049 17.2 0.1 0.009 16.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 RLN48714.1 - 0.033 13.9 0.1 5.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 RLN48714.1 - 0.042 13.6 0.4 0.068 12.9 0.4 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 RLN48714.1 - 0.052 13.9 0.0 0.052 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RLN48714.1 - 0.084 13.3 0.2 0.17 12.3 0.2 1.5 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 RLN48714.1 - 0.11 11.9 0.2 0.24 10.8 0.2 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Thymidylate_kin PF02223.17 RLN48714.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 2 0 0 2 2 2 0 Thymidylate kinase MMR_HSR1 PF01926.23 RLN48714.1 - 0.16 12.1 0.1 0.71 10.0 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRP54 PF00448.22 RLN48714.1 - 0.2 11.3 0.2 0.34 10.5 0.2 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Aa_trans PF01490.18 RLN48715.1 - 3.7e-32 111.6 5.9 5.1e-32 111.1 5.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Tub_N PF16322.5 RLN48716.1 - 0.0049 17.3 2.9 0.0059 17.0 2.9 1.1 1 0 0 1 1 1 1 Tubby N-terminal PEP-utilisers_N PF05524.13 RLN48716.1 - 0.013 15.7 3.1 0.016 15.4 3.1 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Nucleo_P87 PF07267.11 RLN48716.1 - 0.058 12.3 2.8 0.066 12.1 2.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4988 PF16378.5 RLN48716.1 - 0.17 11.6 0.2 0.27 10.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function FXR_C1 PF16096.5 RLN48716.1 - 1.7 8.9 19.8 1.6 9.0 4.0 2.3 1 1 1 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Abhydrolase_3 PF07859.13 RLN48717.1 - 1.5e-34 119.7 0.8 6.7e-31 107.8 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN48717.1 - 1.1e-12 47.6 0.0 2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 RLN48717.1 - 0.00073 19.1 0.0 0.0076 15.7 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 RLN48717.1 - 0.086 12.8 0.0 0.23 11.4 0.0 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PRP38 PF03371.15 RLN48718.1 - 4.4e-52 176.4 0.0 6.1e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 PRP38 family PH PF00169.29 RLN48719.1 - 2.3e-20 73.1 1.9 1.3e-09 38.5 0.2 3.1 2 2 0 2 2 2 2 PH domain PH_11 PF15413.6 RLN48719.1 - 3.4e-06 27.4 7.9 0.0031 17.9 1.5 4.0 2 2 1 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.6 RLN48719.1 - 0.0013 19.0 3.7 0.17 12.2 0.7 3.6 3 1 0 3 3 3 2 Pleckstrin homology domain Enolase_C PF00113.22 RLN48720.1 - 2e-148 493.5 0.0 2.5e-148 493.1 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 RLN48720.1 - 2.7e-57 192.6 0.0 4.5e-57 191.8 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 RLN48720.1 - 4.9e-10 39.3 0.0 8.1e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 RLN48720.1 - 5.1e-07 29.1 0.5 1e-06 28.1 0.1 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus EccE PF11203.8 RLN48720.1 - 0.03 14.6 0.1 2.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE 2_5_RNA_ligase2 PF13563.6 RLN48721.1 - 0.014 15.3 1.7 0.016 15.1 0.6 1.7 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily 2_5_RNA_ligase2 PF13563.6 RLN48722.1 - 0.0063 16.4 3.6 0.026 14.4 3.6 2.0 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 RLN48722.1 - 0.02 15.1 0.5 14 6.0 0.0 3.1 2 1 0 2 2 2 0 LigT like Phosphoesterase OTU PF02338.19 RLN48723.1 - 0.00018 22.0 0.0 0.00023 21.6 0.0 1.2 1 0 0 1 1 1 1 OTU-like cysteine protease Fcf2 PF08698.11 RLN48724.1 - 2.1e-22 79.3 0.1 5.1e-22 78.1 0.1 1.7 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Med3 PF11593.8 RLN48724.1 - 7.9 5.6 8.6 15 4.6 8.6 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Abhydrolase_3 PF07859.13 RLN48725.1 - 6.8e-34 117.6 0.3 1.2e-33 116.8 0.3 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN48725.1 - 6.2e-12 45.1 0.0 9.6e-12 44.4 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 RLN48725.1 - 3.5e-06 26.7 0.0 5.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 RLN48725.1 - 0.00095 18.5 0.2 0.0061 15.9 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 RLN48726.1 - 1.5e-32 113.2 2.3 1.4e-31 110.0 2.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN48726.1 - 9.2e-08 31.3 0.0 1.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Kinesin PF00225.23 RLN48727.1 - 5e-99 331.4 0.1 7.8e-99 330.7 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN48727.1 - 5.6e-27 94.5 0.0 1.5e-26 93.2 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Filament PF00038.21 RLN48727.1 - 0.00068 19.3 4.6 0.00068 19.3 4.6 2.8 3 0 0 3 3 3 1 Intermediate filament protein RILP PF11461.8 RLN48727.1 - 0.031 14.5 0.3 0.14 12.4 0.3 2.2 1 0 0 1 1 1 0 Rab interacting lysosomal protein DUF3138 PF11336.8 RLN48727.1 - 0.17 10.5 5.7 0.1 11.2 3.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) TolA_bind_tri PF16331.5 RLN48727.1 - 1.3 9.1 15.7 2.6 8.2 0.2 4.3 4 1 0 4 4 4 0 TolA binding protein trimerisation Hydin_ADK PF17213.3 RLN48727.1 - 3.3 7.9 8.3 2 8.7 0.0 3.1 2 1 0 2 2 2 0 Hydin Adenylate kinase-like domain WD40_alt PF14077.6 RLN48727.1 - 4.8 7.1 6.4 4 7.4 0.1 3.5 3 0 0 3 3 3 0 Alternative WD40 repeat motif DivIC PF04977.15 RLN48727.1 - 6.4 6.6 14.7 6.6 6.6 0.9 4.7 4 0 0 4 4 4 0 Septum formation initiator Aminotran_4 PF01063.19 RLN48728.1 - 9.3e-13 48.6 0.0 1.2e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV TPR_11 PF13414.6 RLN48730.1 - 0.016 14.8 0.0 0.7 9.6 0.0 2.8 2 0 0 2 2 2 0 TPR repeat zf-CHCC PF10276.9 RLN48731.1 - 9.7e-16 57.5 1.3 1.3e-15 57.1 1.3 1.2 1 0 0 1 1 1 1 Zinc-finger domain Abhydrolase_3 PF07859.13 RLN48732.1 - 2e-34 119.3 1.0 4.9e-33 114.8 1.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN48732.1 - 6.2e-09 35.2 0.0 1.1e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 RLN48732.1 - 0.0024 17.4 0.1 0.0051 16.3 0.1 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family VRR_NUC PF08774.11 RLN48734.1 - 9.1e-11 41.8 0.0 1.9e-07 31.1 0.0 3.2 3 0 0 3 3 3 2 VRR-NUC domain RabGAP-TBC PF00566.18 RLN48736.1 - 0.018 14.7 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain IF-2B PF01008.17 RLN48737.1 - 1e-76 257.9 0.0 1.2e-76 257.6 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Abhydrolase_3 PF07859.13 RLN48738.1 - 1.7e-31 109.8 0.2 2.2e-30 106.1 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN48738.1 - 2.1e-11 43.3 0.0 4.5e-11 42.2 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 RLN48738.1 - 0.039 13.4 0.0 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family UPF0176_N PF17773.1 RLN48739.1 - 2.2e-22 79.2 0.0 4e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 RLN48739.1 - 1.2e-13 51.2 7.3 2.2e-13 50.4 7.3 1.4 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 RLN48739.1 - 1.6e-10 41.4 0.0 3.2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Acylphosphatase PF00708.18 RLN48739.1 - 0.021 15.2 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 Acylphosphatase WW PF00397.26 RLN48740.1 - 2.8e-07 30.5 3.2 6.2e-06 26.2 1.2 2.6 2 0 0 2 2 2 1 WW domain Trypsin_2 PF13365.6 RLN48740.1 - 0.0001 23.2 0.0 0.0002 22.3 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain PUL PF08324.11 RLN48740.1 - 0.0038 16.5 0.5 0.0093 15.2 0.1 1.8 2 0 0 2 2 2 1 PUL domain IQ PF00612.27 RLN48740.1 - 0.17 11.8 7.4 1.8 8.5 1.1 3.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif DDE_1 PF03184.19 RLN48741.1 - 5.3e-38 130.4 1.6 9e-38 129.7 1.6 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN48741.1 - 2e-13 50.2 0.1 5.6e-13 48.7 0.1 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 RLN48741.1 - 1.6e-05 24.5 0.1 4.8e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain OTU PF02338.19 RLN48742.1 - 7e-17 62.1 0.1 2.2e-16 60.5 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 RLN48742.1 - 6.5e-05 22.5 0.6 0.01 15.3 0.0 2.4 1 1 1 2 2 2 2 Peptidase C65 Otubain Abhydrolase_3 PF07859.13 RLN48743.1 - 3.4e-33 115.3 1.2 2.7e-32 112.4 1.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN48743.1 - 1.3e-12 47.3 0.0 2.2e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 RLN48743.1 - 0.0018 17.8 0.1 0.0098 15.4 0.1 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 RLN48743.1 - 0.058 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 HTH_psq PF05225.16 RLN48755.1 - 9.6e-06 25.2 0.3 4.3e-05 23.2 0.1 2.1 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 RLN48755.1 - 0.0025 17.9 0.4 0.0065 16.6 0.4 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 RLN48755.1 - 0.067 13.0 0.3 0.15 11.9 0.3 1.6 1 0 0 1 1 1 0 Homeodomain-like domain BT1 PF03092.16 RLN48759.1 - 2.2e-13 49.3 16.1 1.7e-12 46.4 1.0 3.2 2 1 1 3 3 3 3 BT1 family Zip PF02535.22 RLN48760.1 - 0.00024 20.5 0.9 0.0003 20.1 0.9 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Neur_chan_memb PF02932.16 RLN48760.1 - 0.17 11.9 0.1 0.25 11.4 0.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SieB PF14163.6 RLN48760.1 - 0.22 11.0 0.6 0.55 9.7 0.6 1.7 1 1 0 1 1 1 0 Super-infection exclusion protein B MAP17 PF15807.5 RLN48760.1 - 0.71 10.1 9.4 0.49 10.6 7.6 1.6 1 1 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF789 PF05623.12 RLN48760.1 - 1.2 8.7 6.1 2.4 7.8 6.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF789) Paf1 PF03985.13 RLN48760.1 - 4.2 6.3 22.0 5.7 5.8 22.0 1.2 1 0 0 1 1 1 0 Paf1 Pkinase PF00069.25 RLN48761.1 - 1.8e-40 139.0 0.0 3.3e-26 92.2 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN48761.1 - 2.9e-19 69.4 0.1 8.7e-10 38.3 0.0 2.4 1 1 0 2 2 2 2 Protein tyrosine kinase ATG11 PF10377.9 RLN48761.1 - 1.7e-14 54.0 0.0 7.2e-07 29.3 0.0 3.4 3 1 1 4 4 4 2 Autophagy-related protein 11 ABC1 PF03109.16 RLN48761.1 - 0.0012 19.0 0.1 0.0031 17.7 0.1 1.6 1 0 0 1 1 1 1 ABC1 family zf-RING_2 PF13639.6 RLN48761.1 - 0.0081 16.5 11.6 0.0081 16.5 11.6 3.7 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 RLN48762.1 - 3.3e-10 39.7 12.9 6e-10 38.8 12.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN48762.1 - 3.7e-09 36.8 13.7 7.7e-09 35.8 13.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN48762.1 - 2.6e-08 33.5 14.7 4.9e-08 32.7 14.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN48762.1 - 7.2e-08 32.2 13.0 1.7e-07 31.0 13.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 RLN48762.1 - 9.6e-07 28.6 13.8 1.7e-06 27.7 13.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN48762.1 - 7.1e-06 25.9 12.3 1.5e-05 24.8 12.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 RLN48762.1 - 7.4e-06 26.2 9.1 1.7e-05 25.0 9.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RLN48762.1 - 7.1e-05 22.8 7.0 7.1e-05 22.8 7.0 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 RLN48762.1 - 0.00045 20.0 8.1 0.00099 18.9 8.1 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 RLN48762.1 - 0.00091 19.3 9.1 0.003 17.7 9.4 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 RLN48762.1 - 0.0032 17.5 5.8 0.0061 16.6 5.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 RLN48762.1 - 0.025 14.2 10.1 0.051 13.2 10.1 1.4 1 0 0 1 1 1 0 P-11 zinc finger RecR PF02132.15 RLN48762.1 - 1.3 8.7 8.4 3.3 7.3 2.0 2.6 2 0 0 2 2 2 0 RecR protein zf-RING_11 PF17123.5 RLN48762.1 - 1.7 8.5 12.1 0.55 10.0 6.5 2.6 2 0 0 2 2 2 0 RING-like zinc finger Carboxyl_trans PF01039.22 RLN48764.1 - 5e-152 507.0 0.0 6.1e-152 506.7 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MPC PF03650.13 RLN48765.1 - 6.4e-15 55.3 0.1 7.2e-15 55.1 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DUF1681 PF07933.14 RLN48766.1 - 6.4e-28 97.3 0.0 1.7e-27 95.9 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1681) Orexin PF02072.15 RLN48766.1 - 0.087 12.8 0.1 0.14 12.1 0.1 1.5 1 1 0 1 1 1 0 Prepro-orexin zf-C2H2 PF00096.26 RLN48775.1 - 1.7e-16 59.7 25.2 5e-06 26.7 1.1 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RLN48775.1 - 1.6e-14 53.6 21.6 1.5e-06 28.4 0.2 5.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 RLN48775.1 - 8.8e-10 38.6 23.8 0.0039 17.9 1.1 4.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 RLN48775.1 - 3.9e-05 23.9 7.9 0.058 13.7 0.9 2.8 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 RLN48775.1 - 5e-05 23.0 8.3 0.28 11.0 0.1 3.9 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 RLN48775.1 - 0.0018 18.0 12.4 0.18 11.6 0.7 3.5 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 RLN48775.1 - 0.0065 16.7 0.1 6 7.3 0.0 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 RLN48775.1 - 0.068 13.6 3.0 6.1 7.4 0.2 3.0 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 RLN48775.1 - 0.11 12.5 7.1 1.4 9.0 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 RLN48775.1 - 0.84 9.8 7.8 7.3 6.7 1.7 2.9 2 1 1 3 3 3 0 Aberrant zinc-finger Vanabin-2 PF11437.8 RLN48775.1 - 5.3 7.3 5.9 3.2 8.0 0.2 2.5 1 1 2 3 3 3 0 Vanadium-binding protein 2 PLAC8 PF04749.17 RLN48780.1 - 1.1e-15 58.4 4.6 1.5e-15 58.0 4.6 1.2 1 0 0 1 1 1 1 PLAC8 family DUF1294 PF06961.13 RLN48780.1 - 0.06 13.6 0.3 0.14 12.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) Phage_holin_3_6 PF07332.11 RLN48780.1 - 0.2 11.7 2.5 0.31 11.1 2.5 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III PLAC8 PF04749.17 RLN48781.1 - 7.7e-29 100.6 12.2 4.3e-16 59.7 0.6 2.1 2 0 0 2 2 2 2 PLAC8 family HTH_24 PF13412.6 RLN48781.1 - 0.034 13.7 0.1 9.1 5.9 0.0 3.2 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding TGT PF01702.18 RLN48783.1 - 4.4e-135 450.3 0.0 6.3e-135 449.8 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase COX6B PF02297.17 RLN48783.1 - 4.6e-11 42.8 3.9 4.6e-11 42.8 3.9 1.9 2 0 0 2 2 2 1 Cytochrome oxidase c subunit VIb CHCH PF06747.13 RLN48783.1 - 0.078 13.1 2.0 0.18 12.0 0.6 2.3 2 0 0 2 2 2 0 CHCH domain C2 PF00168.30 RLN48784.1 - 0.092 13.0 0.0 0.14 12.5 0.0 1.4 1 1 0 1 1 1 0 C2 domain T2SSK PF03934.13 RLN48785.1 - 0.091 12.1 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K PH PF00169.29 RLN48786.1 - 0.079 13.5 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 PH domain PH_9 PF15410.6 RLN48786.1 - 0.081 13.3 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Sec23_helical PF04815.15 RLN48787.1 - 8.8e-27 92.9 0.0 1.5e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 RLN48787.1 - 9.9e-19 67.9 0.0 1.7e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_trunk PF04811.15 RLN48787.1 - 8.2e-13 48.5 0.3 2.1e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Gelsolin PF00626.22 RLN48787.1 - 1.4e-08 34.5 0.0 2.5e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat UbiA PF01040.18 RLN48788.1 - 2.1e-56 191.1 17.6 2.9e-56 190.6 17.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family TrbC PF04956.13 RLN48788.1 - 0.02 15.1 1.0 0.02 15.1 1.0 2.4 2 1 0 2 2 2 0 TrbC/VIRB2 family NADH5_C PF06455.11 RLN48788.1 - 0.026 14.1 0.0 0.065 12.8 0.0 1.6 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus KIF1B PF12423.8 RLN48789.1 - 3.8e-06 27.2 0.1 3.8e-06 27.2 0.1 2.5 2 0 0 2 2 2 1 Kinesin protein 1B FHA PF00498.26 RLN48789.1 - 1.4e-05 25.4 0.0 3.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 FHA domain HET-S PF17108.5 RLN48789.1 - 0.13 12.0 1.2 0.31 10.8 1.2 1.6 1 0 0 1 1 1 0 N-terminal small S protein of HET, non-prionic Ndufs5 PF10200.9 RLN48789.1 - 0.15 12.3 2.9 0.24 11.7 0.0 2.8 3 0 0 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Peptidase_S28 PF05577.12 RLN48790.1 - 5.9e-22 78.1 0.6 6.7e-22 77.9 0.6 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Sec23_trunk PF04811.15 RLN48791.1 - 2.4e-42 145.2 0.1 3e-42 144.8 0.1 1.1 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 RLN48791.1 - 2.9e-16 59.2 3.2 4.6e-16 58.6 3.2 1.3 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger MRNIP PF15749.5 RLN48791.1 - 0.042 14.6 0.5 0.073 13.8 0.5 1.4 1 0 0 1 1 1 0 MRN-interacting protein VWA_2 PF13519.6 RLN48791.1 - 0.11 13.2 0.0 1.4 9.6 0.0 2.2 1 1 0 1 1 1 0 von Willebrand factor type A domain Zn_ribbon_recom PF13408.6 RLN48791.1 - 0.63 10.6 3.4 1.1 9.8 3.4 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Peptidase_S28 PF05577.12 RLN48792.1 - 1.6e-80 271.0 0.2 2e-80 270.7 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 RLN48792.1 - 3e-06 26.2 0.0 7.6e-06 24.8 0.0 1.6 2 0 0 2 2 2 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 RLN48792.1 - 0.00047 19.5 0.0 0.00081 18.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN48792.1 - 0.0093 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN48792.1 - 0.0097 15.4 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2920 PF11144.8 RLN48792.1 - 0.038 13.1 0.1 0.068 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Sugar_tr PF00083.24 RLN48793.1 - 1.2e-15 57.4 1.3 1.3e-15 57.2 0.6 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1761 PF08570.10 RLN48793.1 - 0.14 12.5 2.9 0.34 11.2 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) Fe_hyd_lg_C PF02906.14 RLN48794.1 - 1.1e-66 225.0 0.0 6.2e-65 219.2 0.0 2.2 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 RLN48794.1 - 7.2e-09 35.6 0.1 1.4e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 Iron hydrogenase small subunit Tubulin_C PF03953.17 RLN48809.1 - 1.3e-49 167.6 0.1 3.4e-49 166.2 0.1 1.8 1 0 0 1 1 1 1 Tubulin C-terminal domain GAS PF13851.6 RLN48809.1 - 0.001 18.5 9.4 0.001 18.5 9.4 3.7 4 0 0 4 4 4 1 Growth-arrest specific micro-tubule binding HJURP_C PF12347.8 RLN48809.1 - 0.13 12.3 0.2 8.3 6.5 0.0 2.9 3 0 0 3 3 3 0 Holliday junction regulator protein family C-terminal repeat HALZ PF02183.18 RLN48809.1 - 0.18 12.0 12.5 0.56 10.5 0.9 3.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper NPV_P10 PF05531.12 RLN48809.1 - 2 9.0 4.6 41 4.7 0.2 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Unstab_antitox PF09720.10 RLN48809.1 - 8.4 6.5 10.4 7 6.8 0.2 3.7 3 0 0 3 3 3 0 Putative addiction module component SET PF00856.28 RLN48810.1 - 8.9e-06 26.2 3.0 2.8e-05 24.6 0.0 3.0 2 2 0 2 2 2 1 SET domain MULE PF10551.9 RLN48812.1 - 6.1e-13 49.0 0.0 1.3e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Arm PF00514.23 RLN48814.1 - 6.2e-23 80.1 7.3 1.6e-06 27.9 0.0 5.8 6 1 0 6 6 6 4 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 RLN48814.1 - 0.00019 21.0 0.1 1 8.8 0.0 3.1 1 1 2 3 3 3 3 Armadillo-like HEAT_EZ PF13513.6 RLN48814.1 - 0.00021 21.7 1.7 0.003 18.0 0.4 4.4 4 2 2 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.6 RLN48814.1 - 0.00062 20.1 8.6 0.025 14.9 1.2 3.9 1 1 3 4 4 4 1 HEAT repeats HEAT_PBS PF03130.16 RLN48814.1 - 0.0083 16.7 10.3 11 7.0 0.3 5.9 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat HEAT PF02985.22 RLN48814.1 - 0.0087 16.2 5.4 23 5.6 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat Abhydrolase_8 PF06259.12 RLN48814.1 - 0.032 13.9 1.9 0.065 12.9 1.9 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase Atx10homo_assoc PF09759.9 RLN48814.1 - 0.053 13.5 0.4 3.2 7.8 0.1 2.8 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain ACC_epsilon PF13822.6 RLN48814.1 - 4.2 8.1 9.2 1.3 9.8 0.1 3.1 3 1 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit Fas_alpha_ACP PF18325.1 RLN48815.1 - 0.017 15.5 1.6 1.8 8.9 0.0 2.2 1 1 1 2 2 2 0 Fatty acid synthase subunit alpha Acyl carrier domain DUF724 PF05266.14 RLN48837.1 - 0.12 12.2 2.3 0.13 12.1 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Frataxin_Cyay PF01491.16 RLN48839.1 - 1.7e-11 44.2 0.0 9.7e-07 28.8 0.0 2.1 2 0 0 2 2 2 2 Frataxin-like domain DUF3638 PF12340.8 RLN48839.1 - 0.078 12.3 0.2 0.12 11.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) MTCP1 PF08991.10 RLN48840.1 - 5e-13 49.1 11.6 8.4e-13 48.4 11.6 1.3 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type COPI_assoc PF08507.10 RLN48840.1 - 7.9e-08 32.4 4.7 1.1e-07 32.0 4.7 1.2 1 0 0 1 1 1 1 COPI associated protein DUF2678 PF10856.8 RLN48840.1 - 0.011 15.6 1.8 0.023 14.6 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) CAP_GLY PF01302.25 RLN48841.1 - 2.3e-21 75.6 0.8 3.9e-21 74.9 0.8 1.4 1 0 0 1 1 1 1 CAP-Gly domain adh_short PF00106.25 RLN48842.1 - 2.9e-31 108.4 0.0 7.3e-31 107.1 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN48842.1 - 5.1e-17 62.2 0.2 1.4e-16 60.8 0.2 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN48842.1 - 7.8e-08 32.4 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN48842.1 - 0.022 14.2 0.0 0.045 13.2 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Hce2 PF14856.6 RLN48842.1 - 0.15 12.4 0.2 0.25 11.7 0.2 1.3 1 0 0 1 1 1 0 Pathogen effector; putative necrosis-inducing factor adh_short PF00106.25 RLN48843.1 - 7.6e-32 110.4 0.0 5.9e-31 107.4 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN48843.1 - 1.2e-19 70.8 0.1 1.8e-19 70.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN48843.1 - 9e-10 38.7 0.1 1.4e-09 38.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN48843.1 - 0.00012 21.6 0.5 0.00023 20.7 0.2 1.6 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 RLN48843.1 - 0.031 13.6 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 RLN48843.1 - 0.1 12.0 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glyco_transf_4 PF13439.6 RLN48843.1 - 0.27 11.2 3.1 1.9 8.5 2.1 2.3 1 1 1 2 2 2 0 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 RLN48843.1 - 0.96 9.9 3.9 3.4 8.1 3.9 2.1 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain WD40 PF00400.32 RLN48844.1 - 1.3e-23 82.8 4.0 2.3e-06 28.2 0.2 4.7 4 1 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN48844.1 - 5.4e-06 26.6 0.0 0.038 14.3 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Sof1 PF04158.14 RLN48844.1 - 0.00066 19.9 4.6 0.0012 19.0 4.6 1.4 1 0 0 1 1 1 1 Sof1-like domain Ge1_WD40 PF16529.5 RLN48844.1 - 0.1 11.6 0.0 0.3 10.0 0.0 1.8 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FYVE PF01363.21 RLN48845.1 - 8.7e-14 51.4 7.6 1.6e-13 50.6 7.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger TPR_2 PF07719.17 RLN48845.1 - 1.4e-11 43.6 2.3 0.02 15.0 0.0 4.1 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN48845.1 - 3.5e-10 39.2 1.0 0.0003 20.6 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN48845.1 - 6.6e-10 38.4 0.0 0.014 15.2 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN48845.1 - 6.7e-10 38.4 0.0 0.002 18.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN48845.1 - 1.6e-08 34.1 0.5 0.076 12.9 0.0 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN48845.1 - 2.1e-08 33.7 0.0 0.00094 18.8 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.6 RLN48845.1 - 1.8e-07 31.4 0.8 0.00016 21.9 0.7 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat Ank_2 PF12796.7 RLN48845.1 - 8.8e-07 29.4 0.0 2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TPR_16 PF13432.6 RLN48845.1 - 2e-06 28.3 9.2 0.00048 20.7 2.0 4.0 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN48845.1 - 2.4e-06 27.5 0.0 0.029 14.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN48845.1 - 3.7e-06 27.4 0.1 0.00018 21.9 0.1 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat Ank_4 PF13637.6 RLN48845.1 - 1.1e-05 25.8 0.0 3.8e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (many copies) TPR_14 PF13428.6 RLN48845.1 - 1.7e-05 25.2 0.8 0.047 14.5 0.0 5.6 5 1 2 7 7 4 3 Tetratricopeptide repeat Ank_5 PF13857.6 RLN48845.1 - 2e-05 24.8 0.2 0.00055 20.2 0.0 3.1 2 1 1 3 3 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN48845.1 - 0.001 19.4 0.2 0.15 12.5 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat ANAPC3 PF12895.7 RLN48845.1 - 0.0013 18.9 0.0 0.24 11.6 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 RLN48845.1 - 0.0024 18.3 0.1 9.5 7.2 0.1 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Ank_3 PF13606.6 RLN48845.1 - 0.0059 17.0 0.0 0.26 11.9 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Tnp_zf-ribbon_2 PF13842.6 RLN48845.1 - 1.4 9.8 7.7 3.3 8.6 7.7 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Abhydro_lipase PF04083.16 RLN48846.1 - 1e-19 69.8 0.0 2.2e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 RLN48846.1 - 1.3e-10 41.3 0.2 2.4e-10 40.5 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN48846.1 - 0.014 14.7 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 RNA_pol_Rpb5_N PF03871.14 RLN48846.1 - 0.032 14.8 0.0 0.3 11.7 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb5, N-terminal domain MORN PF02493.20 RLN48847.1 - 1.3e-11 43.7 9.3 0.00013 21.6 0.5 3.8 4 0 0 4 4 4 3 MORN repeat VHS PF00790.19 RLN48848.1 - 2.3e-19 69.6 0.0 3.5e-13 49.6 0.0 2.2 2 0 0 2 2 2 2 VHS domain DUF3522 PF12036.8 RLN48849.1 - 0.28 11.5 2.4 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3522) Abhydro_lipase PF04083.16 RLN48850.1 - 2.2e-19 68.8 0.0 5.1e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 RLN48850.1 - 1.2e-14 54.5 0.1 3.2e-14 53.2 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN48850.1 - 0.0012 18.1 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 RNA_pol_Rpb5_N PF03871.14 RLN48850.1 - 0.071 13.7 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain DUF3577 PF12101.8 RLN48850.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3577) TPR_1 PF00515.28 RLN48851.1 - 1.8e-08 33.9 2.4 0.11 12.3 0.2 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN48851.1 - 2.4e-05 24.1 3.0 0.19 11.9 0.1 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN48851.1 - 0.0058 16.3 0.1 0.38 10.5 0.2 2.5 2 0 0 2 2 2 1 TPR repeat Abhydro_lipase PF04083.16 RLN48852.1 - 5.4e-19 67.5 0.0 8.8e-19 66.8 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 RLN48852.1 - 5.6e-13 49.1 0.0 8.6e-13 48.5 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold RNA_pol_Rpb5_N PF03871.14 RLN48852.1 - 0.0031 18.0 0.0 0.015 15.9 0.1 2.1 3 0 0 3 3 3 1 RNA polymerase Rpb5, N-terminal domain Hydrolase_4 PF12146.8 RLN48852.1 - 0.0062 15.8 0.0 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 C166 PF17615.2 RLN48852.1 - 0.065 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function Abhydro_lipase PF04083.16 RLN48853.1 - 4e-21 74.3 0.1 6.9e-21 73.6 0.1 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 RLN48853.1 - 2.6e-10 40.4 1.1 3.4e-10 40.0 1.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold UPF0242 PF06785.11 RLN48854.1 - 0.074 13.2 6.5 0.1 12.7 6.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Tropomyosin PF00261.20 RLN48854.1 - 0.13 11.6 10.7 0.2 11.0 10.7 1.2 1 0 0 1 1 1 0 Tropomyosin Herpes_UL6 PF01763.16 RLN48854.1 - 0.15 10.5 3.7 0.21 10.1 3.7 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like Leu_zip PF15294.6 RLN48854.1 - 0.18 11.3 9.1 0.54 9.7 9.2 1.6 1 1 1 2 2 2 0 Leucine zipper Atg14 PF10186.9 RLN48854.1 - 0.25 10.4 6.3 0.39 9.8 6.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAUS-augmin3 PF14932.6 RLN48854.1 - 0.25 10.9 10.7 0.39 10.2 10.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 APG6_N PF17675.1 RLN48854.1 - 0.33 11.5 15.7 0.7 10.4 15.2 1.7 1 1 1 2 2 2 0 Apg6 coiled-coil region FUSC PF04632.12 RLN48854.1 - 0.36 9.3 14.7 0.5 8.8 14.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 RLN48854.1 - 0.4 10.2 8.1 0.54 9.8 8.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Laminin_I PF06008.14 RLN48854.1 - 0.56 9.9 15.7 0.92 9.2 15.7 1.3 1 0 0 1 1 1 0 Laminin Domain I EMP24_GP25L PF01105.24 RLN48854.1 - 0.73 9.8 3.0 1.3 8.9 3.0 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Tho2 PF11262.8 RLN48854.1 - 0.81 8.8 5.1 1.3 8.1 5.1 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TMF_DNA_bd PF12329.8 RLN48854.1 - 0.89 9.6 10.2 1 9.4 1.1 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding SKA2 PF16740.5 RLN48854.1 - 0.99 9.2 12.0 0.61 9.9 1.0 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Macoilin PF09726.9 RLN48854.1 - 1.2 7.6 12.1 1.7 7.1 12.1 1.1 1 0 0 1 1 1 0 Macoilin family DUF4407 PF14362.6 RLN48854.1 - 1.8 7.8 7.1 2.6 7.3 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cnn_1N PF07989.11 RLN48854.1 - 2.4 8.4 9.3 8.6 6.6 9.3 1.9 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Phage_GP20 PF06810.11 RLN48854.1 - 3.7 7.3 7.7 7.2 6.4 7.7 1.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 TMPIT PF07851.13 RLN48854.1 - 3.8 6.7 6.1 5.3 6.2 6.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF1204 PF06721.11 RLN48854.1 - 4.9 6.5 7.9 7.7 5.9 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) zf-CpG_bind_C PF12269.8 RLN48854.1 - 8.1 6.2 9.3 1 9.1 2.6 2.0 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain PRA1 PF03208.19 RLN48855.1 - 1.8e-13 50.3 4.3 4.4e-13 49.1 4.1 1.6 1 1 1 2 2 2 1 PRA1 family protein NPP1 PF05630.11 RLN48868.1 - 8.8e-67 225.0 0.0 1e-66 224.8 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) NPP1 PF05630.11 RLN48869.1 - 5e-45 154.0 0.1 5.5e-45 153.9 0.1 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) NPP1 PF05630.11 RLN48870.1 - 6.5e-68 228.7 0.0 7.6e-68 228.5 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) NPP1 PF05630.11 RLN48871.1 - 3.7e-67 226.3 0.0 4.2e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) NPP1 PF05630.11 RLN48872.1 - 3.2e-77 259.1 0.0 3.8e-77 258.9 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) NPP1 PF05630.11 RLN48873.1 - 6.5e-71 238.5 0.0 9.2e-71 238.0 0.0 1.2 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Arrestin_C PF02752.22 RLN48873.1 - 3e-11 43.9 0.0 1.3e-08 35.4 0.0 2.9 2 1 1 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 RLN48873.1 - 0.025 14.7 0.0 9.4 6.3 0.0 2.4 1 1 1 2 2 2 0 Arrestin (or S-antigen), N-terminal domain NPP1 PF05630.11 RLN48874.1 - 1.3e-75 253.8 0.0 1.5e-75 253.6 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Peptidase_M55 PF04951.13 RLN48878.1 - 2.8 7.3 6.5 4.7 6.5 6.5 1.3 1 0 0 1 1 1 0 D-aminopeptidase MAP17 PF15807.5 RLN48880.1 - 0.0054 17.0 0.0 0.007 16.6 0.0 1.2 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Phage_Gp23 PF10669.9 RLN48880.1 - 0.02 15.2 0.1 0.029 14.7 0.1 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) OSTbeta PF15048.6 RLN48880.1 - 0.021 15.0 0.3 0.036 14.2 0.2 1.4 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein ETRAMP PF09716.10 RLN48880.1 - 0.041 14.0 0.4 0.061 13.4 0.4 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DsbD_2 PF13386.6 RLN48880.1 - 0.054 13.4 0.0 0.063 13.2 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region SID-1_RNA_chan PF13965.6 RLN48880.1 - 0.082 11.3 0.0 0.082 11.3 0.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Conotoxin PF02950.17 RLN48880.1 - 0.19 12.7 0.3 0.32 12.1 0.3 1.4 1 0 0 1 1 1 0 Conotoxin Glutaredoxin PF00462.24 RLN48881.1 - 5e-17 61.9 0.0 2.1e-08 34.3 0.1 2.2 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin_2 PF13098.6 RLN48881.1 - 0.00096 19.6 0.2 0.001 19.5 0.2 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain GST_N_3 PF13417.6 RLN48881.1 - 0.0071 16.7 0.0 0.018 15.5 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN48881.1 - 0.063 13.6 0.0 0.15 12.3 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_4 PF13462.6 RLN48881.1 - 0.13 12.4 0.1 1.2 9.3 0.1 2.0 2 0 0 2 2 2 0 Thioredoxin CK_II_beta PF01214.18 RLN48882.1 - 1.6e-29 103.0 0.0 8.8e-17 61.5 0.0 2.4 2 0 0 2 2 2 2 Casein kinase II regulatory subunit Pkinase PF00069.25 RLN48882.1 - 4.6e-24 85.2 0.0 7.1e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN48882.1 - 7.4e-24 84.4 0.0 1e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mak10 PF04112.13 RLN48883.1 - 1.6e-29 102.6 0.0 1.5e-28 99.4 0.0 2.3 2 0 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase CAP_N PF01213.19 RLN48883.1 - 0.35 10.3 9.2 1.8 8.0 5.4 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Voltage_CLC PF00654.20 RLN48886.1 - 1.6e-33 116.5 12.7 2e-33 116.1 12.7 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel Abhydrolase_9_N PF15420.6 RLN48886.1 - 0.011 15.7 3.2 0.18 11.8 0.6 2.3 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus TTL PF03133.15 RLN48887.1 - 7.2e-93 310.9 0.0 2.1e-92 309.4 0.0 1.7 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family Myb_DNA-binding PF00249.31 RLN48887.1 - 1.2e-26 92.6 0.2 3.3e-13 49.6 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Ion_trans PF00520.31 RLN48887.1 - 1.5e-20 73.5 15.7 2.4e-20 72.8 15.7 1.2 1 0 0 1 1 1 1 Ion transport protein Myb_DNA-bind_6 PF13921.6 RLN48887.1 - 1.9e-17 63.2 0.2 2.3e-11 43.8 0.0 3.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain Ion_trans_2 PF07885.16 RLN48887.1 - 1.6e-14 53.6 13.4 2.9e-14 52.8 7.4 2.5 2 0 0 2 2 2 1 Ion channel ATPgrasp_YheCD PF14398.6 RLN48887.1 - 5.4e-06 25.8 0.0 0.0012 18.2 0.0 2.5 2 0 0 2 2 2 2 YheC/D like ATP-grasp Myb_DNA-bind_7 PF15963.5 RLN48887.1 - 0.0004 20.2 0.0 0.015 15.2 0.0 2.7 1 1 0 2 2 2 1 Myb DNA-binding like ATPgrasp_ST PF14397.6 RLN48887.1 - 0.0083 15.4 0.0 0.25 10.6 0.0 2.3 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp PKD_channel PF08016.12 RLN48887.1 - 0.02 13.6 8.3 0.033 12.9 8.3 1.3 1 0 0 1 1 1 0 Polycystin cation channel DASH_Spc34 PF08657.10 RLN48887.1 - 0.063 13.1 0.5 0.15 11.9 0.5 1.5 1 0 0 1 1 1 0 DASH complex subunit Spc34 DUF812 PF05667.11 RLN48888.1 - 1.1e-87 295.4 12.6 1.5e-87 295.0 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) MDD_C PF18376.1 RLN48888.1 - 0.22 11.3 2.8 1.7 8.4 0.0 3.0 3 1 1 4 4 4 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain zf-BED PF02892.15 RLN48889.1 - 0.069 13.2 0.2 0.2 11.7 0.2 1.8 1 0 0 1 1 1 0 BED zinc finger FAM176 PF14851.6 RLN48890.1 - 1.9 8.2 7.2 2.5 7.7 0.5 2.1 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.6 RLN48890.1 - 4.4 7.8 15.3 1.4 9.3 2.4 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4670 PF15709.5 RLN48891.1 - 0.003 17.0 8.5 0.0041 16.5 8.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4670) DLEU7 PF15760.5 RLN48891.1 - 0.73 9.3 8.9 0.039 13.4 2.5 1.9 1 1 0 2 2 2 0 Leukemia-associated protein 7 Aminotran_3 PF00202.21 RLN48893.1 - 1.9e-115 385.8 0.0 7.3e-115 383.9 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-III Kinesin PF00225.23 RLN48895.1 - 4.7e-90 301.9 0.1 8.3e-90 301.1 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN48895.1 - 2.4e-33 115.2 0.0 1.2e-32 112.9 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding Taxilin PF09728.9 RLN48895.1 - 0.0018 17.5 12.4 0.0018 17.5 12.4 2.4 2 0 0 2 2 2 1 Myosin-like coiled-coil protein DUF724 PF05266.14 RLN48895.1 - 5.5 6.8 13.1 15 5.3 0.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Pep3_Vps18 PF05131.14 RLN48896.1 - 4.9e-41 140.0 0.0 1.4e-40 138.5 0.0 1.9 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 RLN48896.1 - 1.2e-13 51.1 5.7 2.3e-09 37.2 0.2 3.5 4 0 0 4 4 4 2 Region in Clathrin and VPS zf-RING_11 PF17123.5 RLN48896.1 - 0.053 13.3 0.2 0.14 11.9 0.2 1.7 1 0 0 1 1 1 0 RING-like zinc finger Vps39_2 PF10367.9 RLN48896.1 - 0.13 12.7 0.2 1.9 8.9 0.2 2.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Herpes_U26 PF07402.11 RLN48896.1 - 0.23 11.0 0.2 0.38 10.3 0.2 1.2 1 0 0 1 1 1 0 Human herpesvirus U26 protein GrpE PF01025.19 RLN48896.1 - 0.32 10.7 3.5 6.4 6.4 0.3 2.5 2 0 0 2 2 2 0 GrpE Utp12 PF04003.12 RLN48896.1 - 0.64 10.4 3.1 0.52 10.7 0.4 2.1 2 0 0 2 2 2 0 Dip2/Utp12 Family TPR_MLP1_2 PF07926.12 RLN48896.1 - 3.1 7.9 10.4 5.5 7.1 0.7 3.0 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein PPPI_inhib PF14895.6 RLN48897.1 - 0.009 15.2 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 1 inhibitor FA_desaturase PF00487.24 RLN48908.1 - 2.6e-23 83.2 7.0 3.2e-23 82.9 7.0 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF5379 PF17350.2 RLN48908.1 - 0.014 15.6 0.4 0.028 14.7 0.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5379) SF3A2 PF16835.5 RLN48909.1 - 2.1e-37 127.4 0.0 3.4e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) ubiquitin PF00240.23 RLN48909.1 - 1.3e-08 34.4 0.0 2.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family zf-met PF12874.7 RLN48909.1 - 6.3e-07 29.6 1.3 1.5e-06 28.4 1.3 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 RLN48909.1 - 5.9e-05 23.0 0.1 9.6e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Ubiquitin_2 PF14560.6 RLN48909.1 - 0.047 14.2 0.0 0.23 12.0 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain Peptidase_C54 PF03416.19 RLN48910.1 - 1.6e-05 24.5 0.0 2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C54 PF03416.19 RLN48911.1 - 7.8e-77 258.4 0.0 9.6e-77 258.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 RLN48911.1 - 0.025 14.0 0.1 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 Peptidase family C78 Actin PF00022.19 RLN48912.1 - 9.4e-46 156.2 0.0 1e-45 156.1 0.0 1.0 1 0 0 1 1 1 1 Actin Pkinase_Tyr PF07714.17 RLN48913.1 - 3.8e-65 219.7 0.0 1.9e-40 138.8 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN48913.1 - 7.2e-58 196.0 0.0 3e-36 125.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 RLN48913.1 - 2.5e-08 33.6 0.0 0.0033 16.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 RLN48913.1 - 0.00081 18.8 0.1 0.11 11.9 0.0 2.8 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family HD_assoc PF13286.6 RLN48913.1 - 0.094 13.3 0.2 0.39 11.3 0.2 2.1 1 0 0 1 1 1 0 Phosphohydrolase-associated domain Exo_endo_phos PF03372.23 RLN48926.1 - 0.00078 19.0 0.4 0.0023 17.5 0.1 2.0 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Jacalin PF01419.17 RLN48926.1 - 0.0011 18.9 0.1 0.002 18.0 0.1 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Exo_endo_phos_2 PF14529.6 RLN48926.1 - 0.033 14.0 0.4 7.3 6.5 0.0 3.0 3 0 0 3 3 3 0 Endonuclease-reverse transcriptase DUF4430 PF14478.6 RLN48926.1 - 0.35 11.5 1.8 3.6 8.2 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4430) LZ_Tnp_IS66 PF13007.7 RLN48927.1 - 0.036 14.8 0.4 0.1 13.4 0.4 1.8 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain ENTH PF01417.20 RLN48928.1 - 1.8e-09 37.7 0.0 3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ENTH PF01417.20 RLN48929.1 - 6.3e-06 26.2 0.1 1.1e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 ENTH domain AMP-binding PF00501.28 RLN48930.1 - 1.6e-93 313.7 0.0 1.9e-93 313.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Jacalin PF01419.17 RLN48931.1 - 4.4e-12 46.1 0.1 8.2e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Exo_endo_phos PF03372.23 RLN48931.1 - 0.00022 20.8 0.1 0.00072 19.1 0.1 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Beta-prism_lec PF16458.5 RLN48931.1 - 0.0018 18.3 1.9 0.0064 16.4 0.7 2.2 1 1 1 2 2 2 1 Beta-prism lectin XPG_I PF00867.18 RLN48932.1 - 1.6e-27 95.7 0.9 3.9e-26 91.2 0.0 3.0 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 RLN48932.1 - 8.2e-27 93.6 0.0 1.8e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 RLN48932.1 - 0.025 14.1 9.7 0.017 14.6 3.7 3.3 2 1 1 3 3 3 0 XPG domain containing DUF4200 PF13863.6 RLN48933.1 - 1.2e-33 116.0 21.0 1.2e-33 116.0 21.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) BAR_3 PF16746.5 RLN48933.1 - 0.00011 22.0 8.9 0.00011 22.0 8.9 2.0 1 1 0 2 2 2 1 BAR domain of APPL family CCDC53 PF10152.9 RLN48933.1 - 0.88 10.0 7.5 0.12 12.8 2.1 2.1 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex Ank_2 PF12796.7 RLN48934.1 - 1.6e-53 179.2 18.8 1.8e-13 50.9 0.6 5.2 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN48934.1 - 3.2e-45 152.0 3.2 1.5e-11 44.6 0.2 7.7 4 2 4 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN48934.1 - 2.9e-36 123.1 9.2 5.6e-09 36.1 0.0 7.5 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 RLN48934.1 - 4.5e-32 109.1 13.3 0.00015 22.0 0.0 9.2 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 RLN48934.1 - 1.9e-25 86.1 7.5 0.015 15.8 0.1 8.3 9 0 0 9 9 9 6 Ankyrin repeat WW PF00397.26 RLN48934.1 - 1.9e-07 31.0 0.2 4.3e-07 29.9 0.2 1.6 1 0 0 1 1 1 1 WW domain OrfB_IS605 PF01385.19 RLN48935.1 - 0.035 14.3 1.8 0.16 12.2 2.1 1.9 2 0 0 2 2 2 0 Probable transposase SDA1 PF05285.12 RLN48935.1 - 0.058 12.8 20.9 0.077 12.4 20.9 1.2 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 RLN48935.1 - 1 8.0 12.8 1.9 7.2 12.8 1.5 1 0 0 1 1 1 0 Presenilin Smg8_Smg9 PF10220.9 RLN48935.1 - 1.2 7.3 8.5 1.6 7.0 8.5 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Apt1 PF10351.9 RLN48935.1 - 6.2 5.6 16.7 8.3 5.1 16.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Gar1 PF04410.14 RLN48935.1 - 8.5 6.1 9.9 1.3 8.8 0.6 2.4 2 0 0 2 2 2 0 Gar1/Naf1 RNA binding region AMP-binding PF00501.28 RLN48936.1 - 1.5e-94 317.0 0.0 1.8e-94 316.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Abhydrolase_1 PF00561.20 RLN48937.1 - 1.8e-27 96.6 0.0 2.9e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold TPR_8 PF13181.6 RLN48937.1 - 2e-23 80.6 12.0 0.00071 19.6 0.0 9.7 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 RLN48937.1 - 7.9e-23 78.7 19.9 0.0023 17.9 0.0 10.4 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 RLN48937.1 - 2.4e-20 71.4 8.2 0.00014 21.5 0.0 8.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 RLN48937.1 - 7.1e-20 70.0 18.2 0.012 16.4 0.1 11.0 5 2 5 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 RLN48937.1 - 4.2e-18 65.4 19.1 0.0007 19.8 0.1 9.3 5 4 1 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 RLN48937.1 - 9.7e-16 56.6 13.0 0.0029 17.5 0.1 9.1 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 RLN48937.1 - 8.3e-14 52.0 11.5 0.0026 18.4 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 RLN48937.1 - 2.2e-12 47.3 20.0 0.00017 22.0 0.1 8.3 5 1 2 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 RLN48937.1 - 4.2e-11 42.8 19.5 1.2 9.9 0.1 9.5 10 0 0 10 10 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN48937.1 - 3.4e-10 40.0 16.1 3.6e-07 30.3 0.8 6.1 7 0 0 7 7 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 RLN48937.1 - 2.5e-09 36.9 2.2 0.024 15.0 0.1 7.1 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN48937.1 - 8.6e-09 34.9 2.2 1.6 8.5 0.0 7.7 6 2 2 8 8 8 1 TPR repeat TPR_9 PF13371.6 RLN48937.1 - 8.2e-07 29.1 8.5 0.23 11.7 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 RLN48937.1 - 4.2e-05 24.3 2.1 0.00055 20.6 0.0 3.0 3 0 0 3 3 3 1 Alpha/beta hydrolase family TPR_20 PF14561.6 RLN48937.1 - 5.8e-05 23.4 7.7 0.54 10.6 0.2 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 RLN48937.1 - 0.0013 18.0 7.4 1.2 8.2 2.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat Hydrolase_4 PF12146.8 RLN48937.1 - 0.0069 15.7 0.0 0.02 14.2 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLIC PF05783.11 RLN48937.1 - 0.012 14.5 0.0 1.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) ChAPs PF09295.10 RLN48937.1 - 0.016 14.2 1.7 0.8 8.6 0.1 3.1 2 1 2 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) Esterase PF00756.20 RLN48937.1 - 0.038 13.6 0.0 0.097 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative esterase Ribonuc_red_lgN PF00317.21 RLN48937.1 - 0.044 13.8 1.4 0.17 11.9 0.1 2.5 2 1 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain PGA2 PF07543.12 RLN48937.1 - 0.057 13.4 3.1 0.12 12.4 3.1 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 MIT PF04212.18 RLN48937.1 - 0.93 9.6 3.4 17 5.6 0.0 4.5 6 0 0 6 6 4 0 MIT (microtubule interacting and transport) domain Lipase_3 PF01764.25 RLN48938.1 - 1.3e-19 70.5 0.0 3.1e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) FYVE PF01363.21 RLN48938.1 - 5.2e-18 64.9 22.1 6e-12 45.5 9.9 2.6 2 0 0 2 2 2 2 FYVE zinc finger Caps_synth_GfcC PF06251.11 RLN48938.1 - 0.046 13.3 3.6 0.11 12.1 3.6 1.6 1 0 0 1 1 1 0 Capsule biosynthesis GfcC Rpr2 PF04032.16 RLN48938.1 - 0.088 13.1 9.6 0.35 11.2 3.7 3.5 3 0 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain MerR PF00376.23 RLN48938.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 MerR family regulatory protein FYVE_2 PF02318.16 RLN48938.1 - 2.5 8.3 15.6 7.8 6.7 5.9 3.3 2 0 0 2 2 2 0 FYVE-type zinc finger adh_short_C2 PF13561.6 RLN48939.1 - 5.8e-46 156.9 0.0 9.1e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RLN48939.1 - 6.3e-20 71.5 0.0 1.1e-19 70.6 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase Enoyl_reductase PF12241.8 RLN48939.1 - 0.00024 20.6 0.0 0.059 12.7 0.0 2.2 1 1 0 2 2 2 2 Trans-2-enoyl-CoA reductase catalytic region DUF1776 PF08643.10 RLN48939.1 - 0.16 11.3 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF5421 PF17458.2 RLN48940.1 - 0.34 10.2 2.2 0.51 9.7 2.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5421) RAP1 PF07218.11 RLN48940.1 - 0.59 8.4 7.5 0.73 8.0 7.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BAF250_C PF12031.8 RLN48949.1 - 0.012 14.9 1.9 0.066 12.5 0.2 2.8 3 0 0 3 3 3 0 SWI/SNF-like complex subunit BAF250/Osa ABC2_membrane PF01061.24 RLN48960.1 - 7.3e-36 123.6 23.7 7.3e-36 123.6 23.7 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RLN48960.1 - 3.7e-27 95.5 1.0 1.4e-16 61.2 0.1 2.6 3 0 0 3 3 2 2 ABC transporter RsgA_GTPase PF03193.16 RLN48960.1 - 2.6e-08 34.0 0.6 0.0033 17.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 RLN48960.1 - 1.8e-06 27.6 4.8 0.018 14.8 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN48960.1 - 2.9e-05 24.7 1.0 0.067 13.7 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RLN48960.1 - 7.4e-05 23.0 0.2 0.24 11.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 RLN48960.1 - 9.2e-05 22.9 1.8 0.18 12.2 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.6 RLN48960.1 - 0.00016 21.3 0.4 0.17 11.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN48960.1 - 0.00019 20.7 0.4 0.073 12.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_21 PF13304.6 RLN48960.1 - 0.00028 20.8 0.0 0.57 9.9 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 RLN48960.1 - 0.00099 18.3 0.2 0.0035 16.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC2_membrane_3 PF12698.7 RLN48960.1 - 0.0023 17.1 18.7 0.0023 17.1 18.7 2.4 1 1 0 2 2 2 1 ABC-2 family transporter protein G-alpha PF00503.20 RLN48960.1 - 0.0044 16.2 0.0 0.018 14.2 0.0 1.9 2 1 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 RLN48960.1 - 0.014 15.4 0.9 7 6.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 RLN48960.1 - 0.015 14.8 0.6 13 5.2 0.1 3.3 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 RLN48960.1 - 0.015 15.1 1.2 2.7 7.7 0.5 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 RLN48960.1 - 0.017 15.2 4.2 1.2 9.2 0.8 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain cobW PF02492.19 RLN48960.1 - 0.025 14.2 1.4 0.18 11.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 RLN48960.1 - 0.035 14.1 2.5 2 8.4 0.5 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 RLN48960.1 - 0.061 13.3 0.6 3.2 7.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 RLN48960.1 - 0.065 13.8 0.2 20 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 RLN48960.1 - 0.074 13.0 0.0 10 6.0 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 RLN48960.1 - 0.094 13.1 0.1 15 6.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase PduV-EutP PF10662.9 RLN48960.1 - 0.12 12.1 2.7 2.5 7.9 0.3 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 RLN48960.1 - 0.18 11.5 0.1 17 5.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 RLN48960.1 - 0.18 12.0 0.6 27 5.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 RLN48960.1 - 0.26 11.2 4.8 5.5 6.9 0.3 2.9 3 0 0 3 3 2 0 NACHT domain AAA_10 PF12846.7 RLN48960.1 - 0.4 9.5 0.9 3.6 6.4 0.1 2.2 2 0 0 2 2 2 0 AAA-like domain Ploopntkinase3 PF18751.1 RLN48960.1 - 0.45 10.4 1.9 6 6.7 0.0 2.8 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 ABC2_membrane PF01061.24 RLN48961.1 - 1.2e-29 103.3 30.9 1.2e-29 103.3 30.9 1.8 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN48961.1 - 0.00026 20.8 0.0 0.00026 20.8 0.0 3.0 3 1 0 3 3 3 1 CDR ABC transporter SWIM PF04434.17 RLN48966.1 - 1.6e-05 24.4 0.3 4.2e-05 23.1 0.3 1.7 1 0 0 1 1 1 1 SWIM zinc finger MULE PF10551.9 RLN48966.1 - 0.00019 21.8 0.0 0.0017 18.7 0.0 2.4 2 0 0 2 2 2 1 MULE transposase domain ABC2_membrane_3 PF12698.7 RLN48979.1 - 3.4e-63 213.9 50.3 1.5e-40 139.4 22.7 3.1 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 RLN48979.1 - 1.9e-37 128.9 0.5 1.1e-28 100.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN48979.1 - 1.9e-12 47.6 3.2 2.1e-08 34.3 0.0 3.3 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RLN48979.1 - 5.1e-06 27.1 0.4 0.0035 17.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 RLN48979.1 - 0.00033 20.6 0.5 0.0097 15.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 RLN48979.1 - 0.00069 19.3 2.7 0.0059 16.3 0.4 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 RLN48979.1 - 0.015 15.0 0.4 0.074 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 RLN48979.1 - 0.024 14.3 0.6 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 RLN48979.1 - 0.054 12.3 0.1 0.33 9.7 0.0 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_22 PF13401.6 RLN48979.1 - 0.081 13.2 1.1 2.6 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 RLN48979.1 - 0.11 12.6 1.1 2.2 8.4 0.2 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 RLN48979.1 - 0.13 11.6 0.8 4.1 6.8 0.0 2.5 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Arf PF00025.21 RLN48979.1 - 0.15 11.5 1.0 16 4.9 0.1 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family SRP54 PF00448.22 RLN48979.1 - 0.22 11.2 4.7 5.9 6.5 0.3 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.19 RLN48979.1 - 0.25 10.9 1.9 0.54 9.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 RLN48979.1 - 0.93 9.2 2.2 10 5.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain ABC2_membrane_5 PF13346.6 RLN48979.1 - 2.1 7.9 35.5 0.29 10.7 16.4 3.0 2 0 0 2 2 2 0 ABC-2 family transporter protein ABC2_membrane PF01061.24 RLN48979.1 - 2.4 7.5 55.4 0.99 8.8 19.0 4.2 4 1 0 4 4 4 0 ABC-2 type transporter DUF3584 PF12128.8 RLN48979.1 - 2.6 5.5 3.2 15 2.9 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ABC2_membrane_3 PF12698.7 RLN48980.1 - 9e-23 80.9 25.1 8.1e-22 77.8 25.1 2.3 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 RLN48980.1 - 4.7e-05 22.9 24.6 0.0018 17.8 23.3 2.5 2 0 0 2 2 2 2 ABC-2 type transporter BPD_transp_1 PF00528.22 RLN48980.1 - 8.7 6.0 19.7 52 3.5 19.6 2.3 1 1 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component LRR_9 PF14580.6 RLN48982.1 - 4.3e-15 55.6 3.0 7.3e-15 54.9 3.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 RLN48982.1 - 3.2e-07 30.5 10.6 0.0042 17.5 2.0 3.7 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN48982.1 - 3.3e-05 23.6 3.4 3.3e-05 23.6 3.4 3.0 4 0 0 4 4 4 1 Leucine rich repeat PIH1_CS PF18201.1 RLN48982.1 - 0.077 13.4 0.3 0.26 11.7 0.0 2.0 2 0 0 2 2 2 0 PIH1 CS-like domain Cyclin_N PF00134.23 RLN48983.1 - 3.7e-10 39.6 0.3 9.3e-10 38.3 0.3 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 RLN48983.1 - 0.031 14.3 4.8 0.038 14.0 0.5 2.5 2 0 0 2 2 2 0 Transcription factor TFIIB repeat AA_permease_2 PF13520.6 RLN48984.1 - 1.4e-45 155.9 47.0 2e-45 155.4 47.0 1.2 1 0 0 1 1 1 1 Amino acid permease SK_channel PF03530.14 RLN48985.1 - 1.2e-06 28.5 0.0 2.7e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 RLN48985.1 - 0.0041 17.1 4.1 0.0087 16.0 4.1 1.5 1 0 0 1 1 1 1 Ion channel Mtc PF03820.17 RLN48986.1 - 1.8e-133 444.4 2.0 2e-133 444.2 2.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Ufm1 PF03671.14 RLN48987.1 - 2.2e-13 50.1 0.1 1e-12 47.9 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin fold modifier 1 protein 6PF2K PF01591.18 RLN48990.1 - 2.6e-16 59.6 0.0 3.5e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AMPK1_CBM PF16561.5 RLN48990.1 - 1.5e-13 50.7 0.0 3.3e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase APS_kinase PF01583.20 RLN48990.1 - 0.097 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.6 RLN48990.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 RLN48990.1 - 0.2 11.8 0.1 0.35 11.0 0.1 1.3 1 0 0 1 1 1 0 Torsin PUB PF09409.10 RLN48991.1 - 4.1e-38 129.2 0.0 1.2e-11 44.4 0.0 5.3 5 0 0 5 5 5 4 PUB domain TUDOR_5 PF18359.1 RLN48991.1 - 2.1e-31 107.4 51.8 0.00034 20.3 0.3 11.9 12 0 0 12 12 12 10 Histone methyltransferase Tudor domain 1 DUF1325 PF07039.11 RLN48991.1 - 6.4e-30 103.9 3.6 0.0027 17.8 0.0 11.3 6 2 5 11 11 11 7 SGF29 tudor-like domain Agenet PF05641.12 RLN48991.1 - 2.2e-22 79.3 31.0 0.049 14.1 0.0 14.0 14 0 0 14 14 14 8 Agenet domain LBR_tudor PF09465.10 RLN48991.1 - 3.4e-21 74.8 26.8 0.0018 18.0 0.2 11.5 11 0 0 11 11 11 6 Lamin-B receptor of TUDOR domain DUF4537 PF15057.6 RLN48991.1 - 1.1e-18 67.4 15.5 0.0023 17.9 0.1 10.3 8 2 2 10 10 10 5 Domain of unknown function (DUF4537) 53-BP1_Tudor PF09038.10 RLN48991.1 - 9.7e-15 54.6 30.6 0.42 10.6 0.1 12.1 13 0 0 13 13 13 5 Tumour suppressor p53-binding protein-1 Tudor TUDOR PF00567.24 RLN48991.1 - 1.5e-09 37.9 7.8 0.045 13.8 0.0 8.9 6 3 4 10 10 10 2 Tudor domain TTD PF12148.8 RLN48991.1 - 5.8e-07 29.5 6.8 0.086 12.7 0.3 7.0 5 3 0 6 6 6 1 Tandem tudor domain within UHRF1 Tudor_2 PF18104.1 RLN48991.1 - 6.9e-07 28.8 39.5 0.0026 17.4 0.1 10.0 11 0 0 11 11 11 4 Jumonji domain-containing protein 2A Tudor domain EF-hand_7 PF13499.6 RLN48991.1 - 2.4e-05 24.7 1.1 0.0064 16.9 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN48991.1 - 0.00014 21.5 2.5 0.088 12.8 0.1 4.3 4 0 0 4 4 3 1 EF-hand domain EF-hand_1 PF00036.32 RLN48991.1 - 0.005 16.3 3.1 0.17 11.5 0.1 4.1 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.6 RLN48991.1 - 0.086 12.7 2.5 0.98 9.3 0.2 3.2 3 0 0 3 3 3 0 EF-hand domain pair DUF150_C PF17384.2 RLN48991.1 - 0.5 10.5 22.4 8.5 6.6 0.4 8.5 8 0 0 8 8 8 0 RimP C-terminal SH3 domain Guanylate_cyc PF00211.20 RLN48992.1 - 5.2e-100 332.6 1.1 4.3e-53 179.7 0.1 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 RLN48992.1 - 0.041 13.3 4.2 0.58 9.5 0.5 2.3 2 0 0 2 2 2 0 Heme NO binding associated LRR_8 PF13855.6 RLN48994.1 - 2.8e-34 116.7 50.0 1e-09 38.0 0.8 6.2 1 1 8 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 RLN48994.1 - 1.4e-28 98.4 24.4 8.2e-05 22.9 3.1 8.0 3 1 6 10 10 10 9 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RLN48994.1 - 1.9e-07 30.6 9.7 0.093 12.8 0.1 6.9 6 0 0 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.6 RLN48994.1 - 1.2e-05 24.9 12.5 0.019 14.5 4.8 3.0 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 RLN48994.1 - 0.00017 21.6 21.4 63 4.7 0.1 10.0 10 1 0 10 10 10 0 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 RLN48994.1 - 0.0072 16.3 0.9 6.3 6.9 0.0 4.5 3 1 1 4 4 4 1 RsmF rRNA methyltransferase first C-terminal domain LRR_3 PF07725.12 RLN48994.1 - 0.33 10.9 6.1 5.5 7.0 0.2 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat CSTF_C PF14304.6 RLN48994.1 - 2.5 7.7 6.9 12 5.6 0.9 4.0 3 0 0 3 3 3 0 Transcription termination and cleavage factor C-terminal UEV PF05743.13 RLN48995.1 - 5.9e-30 103.6 0.1 1.2e-29 102.6 0.1 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 RLN48995.1 - 1.8e-19 69.5 0.9 3.5e-19 68.5 0.2 1.8 2 0 0 2 2 2 1 Vps23 core domain UQ_con PF00179.26 RLN48995.1 - 1.2e-05 25.0 0.4 2.7e-05 23.8 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TetR_C_33 PF13305.6 RLN48995.1 - 0.042 14.6 0.0 0.08 13.7 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain SKA2 PF16740.5 RLN48995.1 - 2 8.2 5.6 1.8 8.4 0.7 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 KELK PF15796.5 RLN48996.1 - 0.0031 17.9 6.3 0.0031 17.9 6.3 4.8 5 1 0 5 5 5 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase CBS PF00571.28 RLN48997.1 - 1.7e-06 28.4 0.0 2.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 CBS domain ABC2_membrane PF01061.24 RLN48998.1 - 2.2e-38 131.8 26.7 2.2e-38 131.8 26.7 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RLN48998.1 - 9.3e-17 61.8 0.0 1.4e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 RLN48998.1 - 0.00062 20.2 0.0 0.0013 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 RLN48998.1 - 0.0017 17.6 0.0 0.0041 16.3 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC2_membrane_3 PF12698.7 RLN48998.1 - 0.0068 15.6 33.8 0.084 12.0 33.8 2.2 1 1 0 1 1 1 1 ABC-2 family transporter protein Zeta_toxin PF06414.12 RLN48998.1 - 0.011 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin G-alpha PF00503.20 RLN48998.1 - 0.013 14.7 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit RsgA_GTPase PF03193.16 RLN48998.1 - 0.013 15.4 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 RLN48998.1 - 0.015 15.0 0.3 0.033 13.9 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN48998.1 - 0.046 14.0 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RLN48998.1 - 0.055 13.0 0.1 0.098 12.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain PDR_assoc PF08370.11 RLN48998.1 - 0.081 12.7 9.1 0.045 13.5 1.3 2.8 2 0 0 2 2 2 0 Plant PDR ABC transporter associated VirE PF05272.11 RLN48998.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E DUF5409 PF17421.2 RLN48998.1 - 4.3 8.1 6.3 4.6 8.0 0.4 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5409) ABC2_membrane PF01061.24 RLN48999.1 - 1.2e-31 109.8 27.0 2.1e-31 109.0 27.0 1.4 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN48999.1 - 1.5e-06 28.0 0.7 1.2e-05 25.1 0.0 2.5 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 RLN48999.1 - 0.0024 17.1 19.8 0.0036 16.5 19.8 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein Dioxygenase_C PF00775.21 RLN49004.1 - 1.2e-06 28.1 0.0 2.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase DUF4349 PF14257.6 RLN49004.1 - 0.073 12.5 0.5 0.14 11.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DDOST_48kD PF03345.14 RLN49007.1 - 1.1e-108 363.8 0.0 1.2e-108 363.6 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta baeRF_family12 PF18856.1 RLN49007.1 - 0.2 12.2 0.0 0.39 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 Ank_2 PF12796.7 RLN49008.1 - 5.5e-42 142.3 6.3 1.2e-11 45.0 0.0 5.6 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 RLN49008.1 - 7.4e-35 117.9 20.1 4.8e-06 26.8 0.2 10.6 12 0 0 12 12 12 6 Ankyrin repeat Ank_5 PF13857.6 RLN49008.1 - 3.3e-33 113.3 13.3 1.6e-10 41.0 0.0 7.8 5 3 4 9 9 9 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN49008.1 - 1.2e-32 111.8 16.2 5.3e-09 36.5 0.3 7.8 5 3 4 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN49008.1 - 2.1e-28 95.2 7.5 0.00034 20.8 0.0 11.2 12 0 0 12 12 12 5 Ankyrin repeat DUF2877 PF11392.8 RLN49008.1 - 0.09 13.5 0.0 0.77 10.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) Sec7 PF01369.20 RLN49010.1 - 8e-63 211.4 0.0 1.7e-62 210.3 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 RLN49010.1 - 9.3e-31 106.9 3.1 9.3e-31 106.9 3.1 3.9 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 RLN49010.1 - 0.00013 21.7 0.1 0.00043 20.0 0.1 1.9 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 RLN49010.1 - 0.16 11.8 0.1 6.5 6.7 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) FSA_C PF10479.9 RLN49011.1 - 0.022 12.9 0.0 0.034 12.3 0.0 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RAP1 PF07218.11 RLN49011.1 - 2.6 6.2 7.4 4.4 5.4 7.4 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pterin_bind PF00809.22 RLN49012.1 - 8.3e-87 290.9 0.4 2.5e-86 289.3 0.4 1.9 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 RLN49012.1 - 3.4e-29 101.6 0.0 3.4e-29 101.6 0.0 2.8 2 1 1 3 3 3 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DHHC PF01529.20 RLN49013.1 - 3.9e-27 95.0 14.7 3.9e-27 95.0 14.7 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.6 RLN49013.1 - 0.067 13.1 0.7 0.067 13.1 0.7 2.1 2 0 0 2 2 2 0 Transglutaminase-like superfamily Bromodomain PF00439.25 RLN49014.1 - 1.3e-15 57.2 0.0 2.7e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Bromodomain DUF4887 PF16228.5 RLN49014.1 - 4.7e-05 23.6 5.7 4.7e-05 23.6 5.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4887) AAA_23 PF13476.6 RLN49014.1 - 0.073 13.6 10.1 1.1 9.8 0.3 2.2 2 0 0 2 2 2 0 AAA domain RNA_polI_A34 PF08208.11 RLN49014.1 - 0.13 12.3 22.2 0.026 14.6 6.3 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF1840 PF08895.11 RLN49014.1 - 0.15 12.4 10.2 0.2 12.0 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) ORC_WH_C PF18137.1 RLN49014.1 - 0.3 11.2 7.5 0.3 11.2 1.0 2.2 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Folate_carrier PF01770.18 RLN49014.1 - 0.55 8.9 0.0 0.55 8.9 0.0 1.5 2 0 0 2 2 2 0 Reduced folate carrier DUF2956 PF11169.8 RLN49014.1 - 0.85 9.8 18.9 0.37 11.0 4.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) GAGA_bind PF06217.12 RLN49014.1 - 1.2 9.3 12.2 0.23 11.7 0.8 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family U1snRNP70_N PF12220.8 RLN49014.1 - 1.3 9.7 17.4 0.58 10.8 1.1 2.6 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Mitoc_mL59 PF18126.1 RLN49014.1 - 4.4 7.6 16.6 0.21 11.9 5.7 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein mL59 EIIBC-GUT_N PF03612.14 RLN49014.1 - 4.9 6.9 7.7 0.97 9.1 0.4 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus RNA_pol_Rpc4 PF05132.14 RLN49014.1 - 7.9 6.9 10.5 0.46 10.9 1.7 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 AP3D1 PF06375.11 RLN49014.1 - 8.7 6.6 30.8 2.7 8.2 7.5 2.3 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 FAM178 PF14816.6 RLN49037.1 - 6.1e-06 25.4 2.1 0.0095 15.0 0.0 3.3 4 0 0 4 4 4 2 Family of unknown function, FAM178 Myb_Cef PF11831.8 RLN49038.1 - 5.9e-45 153.7 12.5 5.9e-45 153.7 12.5 3.9 4 1 0 4 4 4 2 pre-mRNA splicing factor component Ectoine_synth PF06339.12 RLN49055.1 - 9.8e-19 67.8 0.0 1.3e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Ectoine synthase MYCBPAP PF14646.6 RLN49056.1 - 1.4e-68 231.8 0.0 1.4e-68 231.8 0.0 3.9 3 1 1 4 4 4 2 MYCBP-associated protein family PGK PF00162.19 RLN49056.1 - 1.1e-16 60.8 1.0 1.9e-07 30.4 0.0 3.7 3 1 0 3 3 3 3 Phosphoglycerate kinase Dynein_C PF18199.1 RLN49057.1 - 1.4e-83 280.7 0.1 8.8e-83 278.0 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 RLN49057.1 - 5.4e-81 271.7 0.4 2.9e-79 266.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RLN49057.1 - 2.5e-76 255.6 3.1 1.7e-74 249.7 0.1 3.2 4 0 0 4 4 4 2 ATP-binding dynein motor region AAA_lid_11 PF18198.1 RLN49057.1 - 2.6e-48 164.0 0.0 5.1e-48 163.0 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 RLN49057.1 - 4.7e-40 137.7 9.0 9.6e-40 136.6 9.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RLN49057.1 - 4.7e-38 129.9 0.6 3.9e-37 127.0 0.0 2.7 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 RLN49057.1 - 0.033 14.2 0.5 0.085 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 RLN49057.1 - 0.25 11.8 0.8 1.8 9.0 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RabGAP-TBC PF00566.18 RLN49058.1 - 1.6e-53 181.5 0.0 2.9e-53 180.7 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Hydrolase_4 PF12146.8 RLN49059.1 - 2e-07 30.5 0.1 8.5e-06 25.2 0.1 2.5 2 2 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 RLN49059.1 - 6.4e-05 22.7 0.0 9.9e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 RLN49059.1 - 0.00025 21.7 0.9 0.00046 20.9 0.9 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 RLN49059.1 - 0.017 14.8 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF900 PF05990.12 RLN49059.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 RLN49059.1 - 0.14 11.7 0.1 12 5.5 0.1 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold SLX9 PF15341.6 RLN49060.1 - 5.3e-15 56.0 12.6 5.3e-15 56.0 12.6 1.7 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 Lung_7-TM_R PF06814.13 RLN49061.1 - 4.3e-07 29.5 3.4 6.7e-07 28.8 3.4 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 RLN49061.1 - 0.00022 20.7 2.0 0.00034 20.1 2.0 1.2 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain WD40 PF00400.32 RLN49062.1 - 0.0039 18.0 0.1 1.5 9.8 0.0 3.8 3 1 0 3 3 3 1 WD domain, G-beta repeat REJ PF02010.15 RLN49063.1 - 2.4e-50 171.6 8.6 1.6e-47 162.4 9.4 2.4 1 1 1 2 2 2 2 REJ domain Tetraspanin PF00335.20 RLN49063.1 - 1.9e-18 67.1 53.6 5.2e-09 36.2 2.4 6.6 7 0 0 7 7 7 5 Tetraspanin family DUF1084 PF06454.11 RLN49063.1 - 4.1e-07 29.6 9.3 2.5e-06 27.1 9.3 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) fn3 PF00041.21 RLN49063.1 - 0.056 13.8 0.5 16 6.0 0.0 3.7 4 0 0 4 4 4 0 Fibronectin type III domain WcbI PF18588.1 RLN49070.1 - 0.028 14.0 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis enzyme WcbI SWM_repeat PF13753.6 RLN49070.1 - 0.17 12.1 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative flagellar system-associated repeat Myb_DNA-binding PF00249.31 RLN49079.1 - 7.6e-11 42.0 0.4 1.4e-10 41.2 0.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN49079.1 - 0.0012 18.7 0.6 0.0026 17.6 0.6 1.4 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 RLN49079.1 - 0.0076 16.5 0.2 0.014 15.6 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain EF-hand_7 PF13499.6 RLN49080.1 - 2.8e-11 43.7 0.5 5.3e-11 42.8 0.5 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN49080.1 - 1.5e-10 39.9 0.3 2.9e-07 29.6 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN49080.1 - 6.6e-08 31.9 0.2 1.3e-06 27.9 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 RLN49080.1 - 1.8e-06 27.7 1.0 0.0039 17.0 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 RLN49080.1 - 0.0015 18.8 0.0 0.0032 17.8 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 RLN49080.1 - 0.0032 16.9 0.3 0.023 14.2 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.7 RLN49080.1 - 0.093 12.7 0.2 0.41 10.6 0.1 1.9 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand ORC3_N PF07034.11 RLN49081.1 - 2.5e-14 53.1 9.1 1.3e-12 47.4 4.2 3.5 3 1 0 3 3 3 2 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 RLN49081.1 - 1.4e-08 34.9 2.8 5.8e-08 32.9 0.5 2.8 2 1 0 2 2 2 1 Origin recognition complex winged helix C-terminal RFC1 PF08519.12 RLN49081.1 - 1.1 9.4 5.1 1.9 8.7 0.1 3.4 4 0 0 4 4 4 0 Replication factor RFC1 C terminal domain CSRNP_N PF16019.5 RLN49082.1 - 0.016 15.2 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Ribosomal_S17e PF00833.18 RLN49083.1 - 2.4e-58 195.4 0.6 2.6e-58 195.3 0.6 1.0 1 0 0 1 1 1 1 Ribosomal S17 Macoilin PF09726.9 RLN49084.1 - 1.6 7.2 10.5 3.4 6.1 10.5 1.4 1 0 0 1 1 1 0 Macoilin family Secretin_N_2 PF07655.13 RLN49084.1 - 5 7.7 21.1 91 3.7 0.0 3.0 2 0 0 2 2 2 0 Secretin N-terminal domain Apt1 PF10351.9 RLN49084.1 - 6 5.6 16.7 0.24 10.2 6.5 2.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain RNA_pol_N PF01194.17 RLN49085.1 - 2e-30 104.9 1.2 2e-30 104.9 1.2 1.8 2 0 0 2 2 2 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 RLN49085.1 - 0.024 14.9 0.6 0.05 13.9 0.6 1.6 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) PIH1 PF08190.12 RLN49087.1 - 4.1e-35 120.7 0.0 8.9e-35 119.6 0.0 1.6 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 RLN49087.1 - 2.6e-15 56.6 0.0 1.5e-14 54.1 0.0 2.2 2 0 0 2 2 2 1 PIH1 CS-like domain CS PF04969.16 RLN49087.1 - 0.018 16.0 0.0 7.3 7.7 0.0 2.6 2 0 0 2 2 2 0 CS domain MethyTransf_Reg PF10119.9 RLN49087.1 - 0.071 13.8 0.0 10 6.9 0.0 2.8 2 0 0 2 2 2 0 Predicted methyltransferase regulatory domain WD40 PF00400.32 RLN49088.1 - 7.9e-10 39.2 12.2 0.098 13.6 1.2 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN49088.1 - 3.4e-06 27.3 0.0 0.33 11.3 0.0 4.6 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LAMTOR5 PF16672.5 RLN49089.1 - 0.025 14.5 0.1 0.032 14.2 0.1 1.3 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 Robl_LC7 PF03259.17 RLN49089.1 - 0.084 12.6 0.1 0.096 12.5 0.1 1.2 1 0 0 1 1 1 0 Roadblock/LC7 domain Ank_2 PF12796.7 RLN49093.1 - 2e-40 137.2 0.0 1.5e-15 57.5 0.0 6.0 3 1 4 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN49093.1 - 1.1e-31 108.8 1.0 4.7e-09 36.6 0.0 7.6 5 1 2 7 7 7 5 Ankyrin repeats (many copies) TIR_2 PF13676.6 RLN49093.1 - 1.8e-30 106.0 0.0 2.5e-16 60.3 0.0 3.2 3 0 0 3 3 3 2 TIR domain Ank_3 PF13606.6 RLN49093.1 - 1.5e-29 98.7 1.6 4.6e-05 23.5 0.0 9.1 8 1 1 9 9 9 5 Ankyrin repeat Ank PF00023.30 RLN49093.1 - 7.6e-28 95.7 9.0 4e-05 23.8 0.0 8.6 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 RLN49093.1 - 2e-23 82.1 3.1 1.7e-06 28.2 0.1 8.6 5 1 4 9 9 9 7 Ankyrin repeats (many copies) TIR PF01582.20 RLN49093.1 - 1.3e-08 34.9 0.1 4.2e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 TIR domain DUF1863 PF08937.11 RLN49093.1 - 1.7e-06 28.4 0.1 0.03 14.7 0.0 3.0 3 1 0 3 3 3 2 MTH538 TIR-like domain (DUF1863) DUF1843 PF08898.10 RLN49093.1 - 0.16 12.5 0.1 3.3 8.3 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) MIP PF00230.20 RLN49094.1 - 1e-56 192.2 7.1 1.2e-56 192.0 7.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 RLN49095.1 - 2.6e-43 148.4 6.2 3.2e-43 148.1 6.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF4401 PF14351.6 RLN49095.1 - 0.045 13.1 3.6 0.075 12.3 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) Polysacc_synt_C PF14667.6 RLN49095.1 - 2.6 8.1 14.9 5.9 6.9 2.4 3.3 1 1 2 3 3 3 0 Polysaccharide biosynthesis C-terminal domain Invasin_D3 PF09134.10 RLN49104.1 - 0.041 14.2 1.5 0.054 13.8 1.5 1.2 1 0 0 1 1 1 0 Invasin, domain 3 Invasin_D3 PF09134.10 RLN49105.1 - 0.0087 16.3 1.9 0.025 14.9 1.4 1.9 2 1 0 2 2 2 1 Invasin, domain 3 TPR_1 PF00515.28 RLN49106.1 - 7e-10 38.3 0.4 0.12 12.3 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN49106.1 - 7.7e-09 35.0 6.2 0.26 11.5 0.4 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 RLN49106.1 - 0.0007 20.1 13.4 0.0054 17.2 0.1 5.3 4 3 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN49106.1 - 0.00078 19.7 13.9 0.0036 17.6 2.0 4.8 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN49106.1 - 0.0035 17.4 0.2 15 6.1 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN49106.1 - 0.011 16.3 3.6 26 5.7 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 RLN49106.1 - 0.031 14.4 1.7 2.1 8.6 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 RLN49106.1 - 0.057 13.5 0.1 0.057 13.5 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 RLN49106.1 - 0.11 12.2 0.1 42 3.9 0.0 3.5 3 1 1 4 4 4 0 TPR repeat TPR_14 PF13428.6 RLN49106.1 - 1 10.4 14.8 18 6.5 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Phage_TAC_3 PF06896.11 RLN49107.1 - 0.23 12.1 2.2 5.6 7.6 0.4 2.4 2 0 0 2 2 2 0 Phage tail assembly chaperone proteins, TAC ENTH PF01417.20 RLN49108.1 - 3.9e-12 46.3 0.0 7.2e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 ENTH domain MetRS-N PF09635.10 RLN49108.1 - 0.086 13.4 0.3 0.29 11.7 0.0 1.8 1 1 1 2 2 2 0 MetRS-N binding domain Glyco_hydro_28 PF00295.17 RLN49109.1 - 3.9e-09 36.0 0.8 4e-09 36.0 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 CBX7_C PF17218.3 RLN49109.1 - 0.1 12.3 1.3 0.18 11.6 1.3 1.4 1 0 0 1 1 1 0 CBX family C-terminal motif Glyco_hydro_28 PF00295.17 RLN49110.1 - 3e-75 253.3 19.9 3.5e-75 253.1 19.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 NosD PF05048.13 RLN49110.1 - 9e-05 21.9 15.1 0.00022 20.6 13.3 2.1 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Metallophos PF00149.28 RLN49113.1 - 6.7e-13 49.6 0.0 1e-12 49.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RLN49113.1 - 0.00038 20.7 0.1 0.018 15.3 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain RVT_1 PF00078.27 RLN49122.1 - 0.065 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C48 PF02902.19 RLN49125.1 - 0.0011 18.8 0.1 0.0024 17.8 0.1 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RecA PF00154.21 RLN49138.1 - 1e-109 366.1 0.5 1.3e-109 365.7 0.5 1.0 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 RLN49138.1 - 4.1e-07 29.5 0.2 7.1e-06 25.5 0.2 2.0 1 1 0 1 1 1 1 Rad51 ATPase_2 PF01637.18 RLN49138.1 - 6.9e-06 26.1 0.0 2.9e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea ATPase PF06745.13 RLN49138.1 - 8.2e-05 22.0 0.1 0.02 14.3 0.1 2.7 1 1 0 1 1 1 1 KaiC AAA_24 PF13479.6 RLN49138.1 - 0.0033 17.2 0.0 0.0048 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 RLN49138.1 - 0.0073 15.9 1.1 0.49 9.9 1.1 2.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 RLN49138.1 - 0.0084 16.5 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN49138.1 - 0.013 15.9 0.1 0.02 15.3 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain CobU PF02283.16 RLN49138.1 - 0.027 14.0 0.0 0.071 12.7 0.0 1.7 1 1 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase ATPgrasp_N PF18130.1 RLN49138.1 - 0.04 14.5 0.3 0.1 13.2 0.1 1.8 2 0 0 2 2 2 0 ATP-grasp N-terminal domain AAA_33 PF13671.6 RLN49138.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain Cyclin_C PF02984.19 RLN49139.1 - 1.1e-22 80.4 0.7 1.4e-22 80.0 0.7 1.2 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 RLN49139.1 - 2e-06 27.6 2.2 0.00014 21.6 0.2 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain PPP4R2 PF09184.11 RLN49150.1 - 5.5 6.5 14.3 6.7 6.2 14.3 1.2 1 0 0 1 1 1 0 PPP4R2 Hid1 PF12722.7 RLN49150.1 - 5.7 4.9 10.1 6.1 4.8 10.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CobT PF06213.12 RLN49150.1 - 5.9 6.2 8.5 7.6 5.8 8.5 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Aconitase PF00330.20 RLN49152.1 - 0.16 11.0 0.8 0.25 10.3 0.8 1.2 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) THF_DHG_CYH PF00763.23 RLN49156.1 - 3e-20 72.6 0.0 7e-20 71.4 0.0 1.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 RLN49156.1 - 9.9e-15 54.2 0.9 3.5e-11 42.7 0.9 3.8 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RRP7 PF12923.7 RLN49158.1 - 2.8e-24 85.5 12.8 3.2e-18 66.0 5.0 2.2 2 0 0 2 2 2 2 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_1 PF00076.22 RLN49158.1 - 0.0012 18.6 0.0 0.0043 16.8 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 RLN49158.1 - 0.0061 16.4 0.0 0.0095 15.8 0.0 1.4 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain APP_E2 PF12925.7 RLN49158.1 - 0.028 14.1 0.6 0.052 13.2 0.6 1.4 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein Ribosomal_L7Ae PF01248.26 RLN49159.1 - 5.3e-20 71.0 0.0 8.6e-20 70.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Anoctamin PF04547.12 RLN49160.1 - 1e-33 116.9 6.2 1.2e-33 116.6 6.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 RLN49160.1 - 3.6e-18 66.1 0.0 5.3e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF3938 PF13074.6 RLN49160.1 - 0.13 12.5 0.5 0.25 11.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) PH PF00169.29 RLN49161.1 - 0.013 16.0 0.4 0.041 14.4 0.4 1.9 1 1 0 1 1 1 0 PH domain DICT PF10069.9 RLN49161.1 - 0.11 12.2 0.3 11 5.8 0.0 2.2 2 0 0 2 2 2 0 Sensory domain in DIguanylate Cyclases and Two-component system DUF4981 PF16353.5 RLN49162.1 - 0.0013 19.2 0.0 0.0024 18.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) GCP_C_terminal PF04130.13 RLN49164.1 - 1.2e-17 64.4 0.4 1.7e-17 63.9 0.4 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 RLN49164.1 - 2.6e-05 24.0 0.5 0.00057 19.6 0.0 2.3 2 1 1 3 3 3 1 Gamma tubulin complex component N-terminal LAGLIDADG_2 PF03161.13 RLN49164.1 - 0.02 14.9 0.0 0.053 13.5 0.0 1.7 1 1 1 2 2 2 0 LAGLIDADG DNA endonuclease family DUF2063 PF09836.9 RLN49164.1 - 0.098 12.9 0.0 0.23 11.7 0.0 1.6 1 1 0 1 1 1 0 Putative DNA-binding domain GCP_C_terminal PF04130.13 RLN49165.1 - 3e-11 43.4 4.9 1.5e-05 24.6 0.3 2.3 1 1 1 2 2 2 2 Gamma tubulin complex component C-terminal DUF4486 PF14858.6 RLN49166.1 - 3.3e-17 62.2 0.3 7.5e-17 61.0 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4486) TPR_8 PF13181.6 RLN49166.1 - 0.039 14.2 0.1 88 3.7 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat fn3 PF00041.21 RLN49166.1 - 0.049 14.0 0.1 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 Fibronectin type III domain HLH PF00010.26 RLN49166.1 - 0.15 12.1 0.1 0.56 10.2 0.1 2.1 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain TPR_2 PF07719.17 RLN49166.1 - 3.8 7.9 9.4 3.1 8.1 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN49166.1 - 9.6 6.6 12.7 60 4.0 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat OxoGdeHyase_C PF16870.5 RLN49170.1 - 3.4e-20 72.3 0.0 3.7e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal Pkinase_Tyr PF07714.17 RLN49171.1 - 3.1e-11 43.0 0.4 3.5e-11 42.9 0.4 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN49171.1 - 5.2e-09 35.9 0.1 6.1e-09 35.6 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain CCDC66 PF15236.6 RLN49172.1 - 0.0002 21.3 54.0 0.001 18.9 2.6 4.4 3 1 1 4 4 4 2 Coiled-coil domain-containing protein 66 TGase_elicitor PF16683.5 RLN49173.1 - 2.3e-181 602.4 0.4 3.6e-181 601.7 0.4 1.3 1 0 0 1 1 1 1 Transglutaminase elicitor Cu-oxidase_2 PF07731.14 RLN49182.1 - 3.8e-35 120.6 1.9 4.8e-28 97.6 0.0 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN49182.1 - 3.6e-31 107.7 3.2 9.2e-30 103.1 0.3 3.1 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 RLN49182.1 - 6e-25 88.2 0.0 8.4e-24 84.5 0.0 2.7 2 1 0 2 2 2 1 Multicopper oxidase Annexin PF00191.20 RLN49182.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Annexin Cu-oxidase_2 PF07731.14 RLN49183.1 - 1.2e-35 122.2 9.1 6.9e-29 100.3 0.8 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN49183.1 - 3e-32 111.1 5.4 8.9e-32 109.6 0.2 3.3 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 RLN49183.1 - 1e-26 93.9 0.1 4.2e-26 92.0 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Ion_trans_2 PF07885.16 RLN49186.1 - 1.8e-11 43.8 20.3 1.1e-08 34.9 3.8 4.4 5 0 0 5 5 5 2 Ion channel Ion_trans PF00520.31 RLN49186.1 - 1.4e-10 40.8 20.7 1.1e-05 24.8 10.8 2.4 2 0 0 2 2 2 2 Ion transport protein cNMP_binding PF00027.29 RLN49186.1 - 8.4e-08 32.2 0.0 1.9e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF2304 PF10066.9 RLN49186.1 - 3.9 7.7 9.2 0.11 12.7 1.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) NPP1 PF05630.11 RLN49199.1 - 6.6e-29 101.4 0.8 8.9e-29 101.0 0.8 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Metallophos PF00149.28 RLN49200.1 - 0.005 17.4 0.0 0.0089 16.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DDE_Tnp_1_7 PF13843.6 RLN49201.1 - 2.1e-24 86.5 0.0 4.2e-18 65.8 0.0 2.2 2 0 0 2 2 2 2 Transposase IS4 PTH2 PF01981.16 RLN49202.1 - 2.6e-46 156.7 0.5 3.5e-46 156.3 0.5 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 HTH_ParB PF17762.1 RLN49202.1 - 0.0069 16.2 0.2 0.015 15.1 0.2 1.5 1 0 0 1 1 1 1 HTH domain found in ParB protein TPR_14 PF13428.6 RLN49202.1 - 0.007 17.1 1.1 0.023 15.5 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN49202.1 - 0.02 15.5 0.1 0.02 15.5 0.1 2.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 RLN49202.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 TPR repeat Metallophos PF00149.28 RLN49203.1 - 7.3e-09 36.4 0.1 1.4e-08 35.5 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Arm PF00514.23 RLN49204.1 - 1.6e-46 155.0 23.3 5.5e-05 23.0 0.2 10.7 10 0 0 10 10 10 9 Armadillo/beta-catenin-like repeat Pkinase_Tyr PF07714.17 RLN49204.1 - 7.7e-42 143.4 0.0 1.4e-41 142.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN49204.1 - 2.2e-36 125.6 0.0 4.4e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Arm_2 PF04826.13 RLN49204.1 - 1.3e-10 41.2 0.0 8.3e-05 22.2 0.0 4.4 2 1 1 3 3 3 3 Armadillo-like HEAT_EZ PF13513.6 RLN49204.1 - 8.2e-10 39.0 22.8 0.089 13.3 1.0 7.7 5 2 2 7 7 7 5 HEAT-like repeat HEAT PF02985.22 RLN49204.1 - 2.9e-06 27.1 10.7 1.1 9.7 0.0 8.1 8 0 0 8 8 8 2 HEAT repeat Atx10homo_assoc PF09759.9 RLN49204.1 - 0.0002 21.3 0.3 2.5 8.2 0.0 4.2 3 1 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain ABC1 PF03109.16 RLN49204.1 - 0.00021 21.4 0.0 0.00067 19.8 0.0 1.8 1 0 0 1 1 1 1 ABC1 family UNC45-central PF11701.8 RLN49204.1 - 0.0037 17.2 1.5 5.7 6.9 0.0 4.4 4 1 0 4 4 4 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.6 RLN49204.1 - 0.0073 16.7 3.3 0.0073 16.7 3.3 6.1 3 1 4 8 8 7 4 HEAT repeats APH PF01636.23 RLN49204.1 - 0.04 13.8 0.7 0.45 10.4 0.0 3.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Cnd1 PF12717.7 RLN49204.1 - 0.089 12.8 0.1 0.62 10.1 0.0 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Amastin PF07344.11 RLN49204.1 - 0.26 11.1 5.6 0.88 9.4 2.2 2.5 2 0 0 2 2 2 0 Amastin surface glycoprotein HEAT_PBS PF03130.16 RLN49204.1 - 0.91 10.4 25.2 2.8 8.9 0.0 8.6 8 0 0 8 8 8 0 PBS lyase HEAT-like repeat Pox_F11 PF04943.12 RLN49204.1 - 0.93 8.5 3.4 1.6 7.7 3.4 1.3 1 0 0 1 1 1 0 Poxvirus F11 protein adh_short PF00106.25 RLN49205.1 - 8.6e-33 113.4 0.2 2.9e-24 85.6 0.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN49205.1 - 9.9e-20 71.1 0.1 4.2e-15 55.9 0.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN49205.1 - 7.8e-05 22.7 0.1 0.00012 22.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN49205.1 - 0.021 14.3 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 RLN49205.1 - 0.043 14.0 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NmrA PF05368.13 RLN49205.1 - 0.052 13.1 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 RLN49205.1 - 0.057 12.5 0.0 0.097 11.7 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain CBM_6 PF03422.15 RLN49205.1 - 0.065 13.5 0.0 0.17 12.2 0.0 1.7 2 0 0 2 2 2 0 Carbohydrate binding module (family 6) Oxidored_FMN PF00724.20 RLN49206.1 - 3.4e-80 269.9 0.0 3.9e-80 269.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ADH_zinc_N_2 PF13602.6 RLN49209.1 - 2.1e-23 83.8 0.0 3.2e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 RLN49209.1 - 4.9e-15 55.7 0.1 7e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 RLN49209.1 - 0.0044 16.8 0.0 0.009 15.8 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2855) TrkA_N PF02254.18 RLN49209.1 - 0.022 15.0 0.0 0.036 14.3 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 RLN49209.1 - 0.023 14.0 0.4 0.023 14.0 0.4 1.3 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 RLN49209.1 - 0.023 14.1 0.1 0.035 13.6 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.21 RLN49209.1 - 0.027 13.9 0.0 0.035 13.6 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ELFV_dehydrog PF00208.21 RLN49209.1 - 0.069 12.9 0.3 0.15 11.8 0.2 1.6 1 1 1 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_zinc_N_2 PF13602.6 RLN49211.1 - 5.6e-22 79.2 0.1 8.5e-22 78.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 RLN49211.1 - 2.2e-14 53.5 0.1 3.2e-14 53.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 RLN49211.1 - 0.0071 16.1 0.1 0.0085 15.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) adh_short PF00106.25 RLN49211.1 - 0.019 14.4 0.1 0.03 13.8 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.18 RLN49211.1 - 0.021 15.1 0.0 0.036 14.3 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 RLN49211.1 - 0.022 14.1 0.4 0.023 14.0 0.4 1.3 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.21 RLN49211.1 - 0.025 14.0 0.1 0.034 13.6 0.1 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ELFV_dehydrog PF00208.21 RLN49211.1 - 0.047 13.4 0.3 0.14 11.8 0.2 1.7 1 1 1 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NFACT-C PF11923.8 RLN49215.1 - 6e-33 112.9 0.1 6e-33 112.9 0.1 3.2 4 0 0 4 4 4 1 NFACT protein C-terminal domain FbpA PF05833.11 RLN49215.1 - 5.3e-31 107.9 10.2 5.3e-31 107.9 10.2 2.6 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 RLN49215.1 - 3.2e-30 105.0 0.4 9e-30 103.5 0.0 2.1 2 0 0 2 2 2 1 NFACT protein RNA binding domain DUF5590 PF17881.1 RLN49215.1 - 0.085 13.0 0.0 0.085 13.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5590) YrhK PF14145.6 RLN49216.1 - 6e-33 112.5 28.7 4.6e-14 52.0 5.9 3.2 3 0 0 3 3 3 3 YrhK-like protein DUF3533 PF12051.8 RLN49216.1 - 0.059 12.3 13.6 0.42 9.5 1.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3533) TTL PF03133.15 RLN49218.1 - 4.5e-85 285.3 0.0 5.8e-85 285.0 0.0 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RLN49218.1 - 5.9e-07 29.0 0.0 0.0016 17.8 0.0 2.5 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RLN49218.1 - 0.00077 18.8 0.0 0.0091 15.3 0.0 2.1 2 1 0 2 2 2 1 Sugar-transfer associated ATP-grasp PX PF00787.24 RLN49219.1 - 3.6e-05 23.7 0.2 0.00019 21.4 0.2 2.1 1 1 0 1 1 1 1 PX domain IQ PF00612.27 RLN49219.1 - 0.086 12.7 0.1 0.3 11.0 0.1 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif zf-MYND PF01753.18 RLN49220.1 - 6.8e-11 42.1 10.0 6.8e-11 42.1 10.0 2.7 2 1 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 RLN49220.1 - 0.0036 17.6 5.8 0.0036 17.6 5.8 2.3 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding NST1 PF13945.6 RLN49220.1 - 2.1 8.4 7.5 0.94 9.5 2.5 2.5 2 0 0 2 2 2 0 Salt tolerance down-regulator HA2 PF04408.23 RLN49221.1 - 5.1e-26 91.1 0.2 1.1e-25 90.0 0.2 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RLN49221.1 - 2.6e-19 69.4 0.0 1.2e-18 67.2 0.0 2.2 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 RLN49221.1 - 7.2e-10 39.2 0.0 1.7e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RLN49221.1 - 6.8e-08 32.5 0.3 1.5e-07 31.3 0.3 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 RLN49221.1 - 9.8e-07 28.1 0.0 1.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 RLN49221.1 - 3.5e-06 27.4 0.2 6.9e-06 26.5 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RLN49221.1 - 1.1e-05 25.7 0.0 3.7e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 RLN49221.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Herpes_ori_bp PF02399.15 RLN49221.1 - 0.0017 16.5 0.1 0.0025 15.9 0.1 1.1 1 0 0 1 1 1 1 Origin of replication binding protein AAA_30 PF13604.6 RLN49221.1 - 0.0026 17.5 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 RLN49221.1 - 0.01 15.1 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 RLN49221.1 - 0.016 14.7 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 RLN49221.1 - 0.025 14.6 0.1 0.54 10.2 0.1 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 RLN49221.1 - 0.025 14.5 0.3 0.17 11.8 0.1 2.5 2 1 0 2 2 2 0 NACHT domain Helicase_RecD PF05127.14 RLN49221.1 - 0.036 13.9 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Helicase AAA_11 PF13086.6 RLN49221.1 - 0.037 13.8 0.1 0.072 12.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 RLN49221.1 - 0.038 13.7 0.0 0.39 10.4 0.0 2.5 3 0 0 3 3 2 0 Thymidylate kinase Sigma54_activ_2 PF14532.6 RLN49221.1 - 0.044 13.9 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 RLN49221.1 - 0.055 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 RLN49221.1 - 0.062 12.2 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 RLN49221.1 - 0.064 13.8 0.1 0.25 11.9 0.1 2.1 1 1 0 1 1 1 0 ABC transporter TsaE PF02367.17 RLN49221.1 - 0.068 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 RLN49221.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 RLN49221.1 - 0.099 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DAP3 PF10236.9 RLN49221.1 - 0.12 11.6 0.3 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Viral_helicase1 PF01443.18 RLN49221.1 - 0.14 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PIF1 PF05970.14 RLN49221.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase DEAD PF00270.29 RLN49222.1 - 3.7e-37 127.8 0.2 5.7e-37 127.2 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN49222.1 - 6.2e-25 87.7 0.0 5.4e-24 84.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN49222.1 - 3.8e-05 23.7 0.0 6.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 RLN49222.1 - 0.0031 16.8 0.0 0.0052 16.0 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SNF2_N PF00176.23 RLN49222.1 - 0.006 15.4 0.0 0.0086 14.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 RLN49222.1 - 0.081 13.2 0.3 0.48 10.7 0.3 2.2 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 RLN49222.1 - 0.089 12.1 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Dicer_dimer PF03368.14 RLN49223.1 - 4.5e-21 74.8 0.1 9.6e-21 73.8 0.1 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.29 RLN49223.1 - 2.8e-18 66.3 0.0 4.5e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 RLN49223.1 - 1.2e-12 48.2 0.0 2.3e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RLN49223.1 - 1.3e-08 35.2 0.6 1.9e-07 31.4 0.2 2.9 2 1 0 2 2 2 1 Helicase conserved C-terminal domain IstB_IS21 PF01695.17 RLN49223.1 - 3.2e-05 23.7 0.1 0.00014 21.6 0.0 2.1 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 RLN49223.1 - 0.0041 17.4 0.0 0.017 15.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 RLN49223.1 - 0.018 15.6 0.0 0.25 11.9 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 RLN49223.1 - 0.039 13.5 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 RLN49223.1 - 0.041 13.3 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 RLN49223.1 - 0.054 13.9 0.0 0.67 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 RLN49223.1 - 0.054 13.2 0.0 0.32 10.7 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Period_C PF12114.8 RLN49223.1 - 0.057 13.0 2.6 4.5 6.8 0.2 2.4 2 0 0 2 2 2 0 Period protein 2/3C-terminal region DUF2075 PF09848.9 RLN49223.1 - 0.077 12.2 0.0 0.18 11.0 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 RLN49223.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Radial_spoke PF04712.12 RLN49224.1 - 7.2e-11 41.7 0.0 1.3e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Radial spokehead-like protein GBP PF02263.19 RLN49225.1 - 6.4e-43 146.9 0.0 2.8e-42 144.8 0.0 2.1 2 1 0 2 2 2 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 RLN49225.1 - 1.2e-08 34.8 0.0 1.2e-08 34.8 0.0 4.2 3 1 1 4 4 4 1 Guanylate-binding protein, C-terminal domain YafO_toxin PF13957.6 RLN49225.1 - 0.0046 17.0 2.0 0.015 15.3 2.0 1.9 1 0 0 1 1 1 1 Toxin YafO, type II toxin-antitoxin system Patatin PF01734.22 RLN49226.1 - 3e-23 83.1 0.0 5.6e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3336 PF11815.8 RLN49226.1 - 3.8e-16 59.1 0.9 2.4e-08 33.8 0.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF3336) Acyl-CoA_dh_1 PF00441.24 RLN49227.1 - 5.1e-44 150.1 2.0 2e-41 141.7 0.2 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RLN49227.1 - 1.7e-26 92.2 0.0 3.5e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RLN49227.1 - 6.3e-12 45.9 0.0 1.5e-09 38.2 0.0 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RLN49227.1 - 1.3e-05 25.8 0.0 3.3e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain DNA_pol_phi PF04931.13 RLN49243.1 - 0.26 9.3 5.6 0.27 9.3 5.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Astro_capsid_p PF12226.8 RLN49243.1 - 0.51 9.4 6.1 0.56 9.3 6.1 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NOA36 PF06524.12 RLN49243.1 - 1.2 8.4 6.4 1.3 8.2 6.4 1.1 1 0 0 1 1 1 0 NOA36 protein Abhydrolase_1 PF00561.20 RLN49245.1 - 1e-24 87.6 0.0 6.7e-24 84.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN49245.1 - 8.8e-19 69.0 1.7 1.1e-18 68.6 1.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN49245.1 - 1.7e-06 27.5 0.0 2.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 RLN49245.1 - 9.8e-05 22.7 0.2 9.8e-05 22.7 0.2 1.7 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 RLN49246.1 - 9e-24 84.5 0.0 2.3e-23 83.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN49246.1 - 5.5e-18 66.4 1.3 7.7e-18 65.9 1.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN49246.1 - 2.5e-07 30.2 0.0 1.9e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 MRP-L47 PF06984.13 RLN49248.1 - 3.4e-26 91.2 0.3 4.5e-26 90.8 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 RLN49248.1 - 4.5e-11 42.6 3.1 8.7e-11 41.6 3.1 1.5 1 0 0 1 1 1 1 Ribosomal L29 protein DUF3585 PF12130.8 RLN49248.1 - 0.73 10.0 5.6 2.2 8.4 5.6 1.7 1 1 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain ELFV_dehydrog PF00208.21 RLN49249.1 - 2.5e-55 187.9 0.0 4.8e-55 186.9 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 RLN49249.1 - 2.2e-18 65.3 0.1 1.8e-09 35.7 0.1 2.3 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 RLN49249.1 - 0.0085 16.0 0.0 0.033 14.1 0.0 1.9 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-oxoacid_dh PF00198.23 RLN49250.1 - 2.3e-54 184.3 0.0 3e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 RLN49250.1 - 3e-14 52.6 0.7 7.4e-14 51.3 0.7 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 RLN49250.1 - 6.1e-12 45.7 1.0 6.1e-12 45.7 1.0 2.3 2 0 0 2 2 2 1 e3 binding domain HlyD_3 PF13437.6 RLN49250.1 - 0.11 13.2 3.8 0.17 12.6 0.1 2.8 2 2 0 2 2 2 0 HlyD family secretion protein Glyco_transf_22 PF03901.17 RLN49260.1 - 2.3e-13 50.2 0.1 2.5e-13 50.0 0.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Myb_DNA-bind_4 PF13837.6 RLN49269.1 - 5.8e-06 26.6 0.0 0.072 13.5 0.0 2.3 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 RLN49269.1 - 0.00039 20.4 0.5 0.13 12.4 0.0 2.3 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 RLN49269.1 - 0.0021 19.0 0.1 0.73 10.9 0.0 2.3 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 RLN49269.1 - 0.0034 17.7 2.0 2 8.8 0.2 3.1 2 1 1 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like MFS_2 PF13347.6 RLN49270.1 - 3.3e-11 42.4 12.9 3.3e-11 42.4 12.9 2.4 2 1 0 2 2 2 1 MFS/sugar transport protein HR1 PF02185.16 RLN49271.1 - 0.012 15.7 0.1 0.038 14.1 0.1 1.8 1 0 0 1 1 1 0 Hr1 repeat FAM60A PF15396.6 RLN49271.1 - 0.083 12.9 4.3 0.12 12.4 4.3 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Zip PF02535.22 RLN49271.1 - 0.17 11.1 2.2 0.21 10.8 2.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Rab3-GTPase_cat PF13890.6 RLN49280.1 - 3.9e-54 182.7 0.6 7.5e-54 181.7 0.6 1.5 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit bZIP_2 PF07716.15 RLN49282.1 - 0.00039 20.4 6.7 0.00039 20.4 6.7 2.4 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 RLN49282.1 - 0.0031 17.6 13.7 0.0078 16.3 13.3 1.9 1 1 1 2 2 2 1 bZIP transcription factor ATG16 PF08614.11 RLN49282.1 - 0.014 15.7 8.5 0.021 15.1 8.5 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) bZIP_Maf PF03131.17 RLN49282.1 - 0.026 15.0 16.2 0.044 14.3 15.0 2.0 1 1 1 2 2 2 0 bZIP Maf transcription factor KIAA1430 PF13879.6 RLN49282.1 - 0.23 12.3 4.6 0.22 12.3 2.0 2.1 1 1 1 2 2 2 0 KIAA1430 homologue GREB1 PF15782.5 RLN49282.1 - 3.7 4.5 8.5 5.1 4.1 8.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3824 PF12868.7 RLN49282.1 - 7.5 7.2 6.0 6.2 7.5 2.1 2.5 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) JmjN PF02375.17 RLN49286.1 - 1e-17 63.8 0.2 1.8e-17 63.0 0.2 1.4 1 0 0 1 1 1 1 jmjN domain ARID PF01388.21 RLN49286.1 - 8.6e-15 55.2 0.0 1.5e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Pkinase PF00069.25 RLN49287.1 - 1.2e-18 67.5 0.0 1.5e-12 47.4 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain HEAT PF02985.22 RLN49287.1 - 3.1e-13 48.8 7.3 0.21 11.9 0.0 6.7 6 0 0 6 6 6 4 HEAT repeat WD40 PF00400.32 RLN49287.1 - 1e-10 42.0 7.4 0.00032 21.4 0.0 6.6 6 0 0 6 6 6 2 WD domain, G-beta repeat HEAT_2 PF13646.6 RLN49287.1 - 6.2e-08 32.9 0.3 0.017 15.5 0.0 5.6 3 2 3 6 6 6 2 HEAT repeats Pkinase_Tyr PF07714.17 RLN49287.1 - 5e-06 26.0 0.0 0.00031 20.1 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase HEAT_EZ PF13513.6 RLN49287.1 - 0.00024 21.5 0.3 0.13 12.9 0.1 3.9 3 0 0 3 3 3 1 HEAT-like repeat ANAPC4_WD40 PF12894.7 RLN49287.1 - 0.00079 19.7 0.8 1.8 8.9 0.1 4.0 3 1 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Tti2 PF10521.9 RLN49287.1 - 0.0027 17.3 0.1 0.0091 15.6 0.1 1.9 1 1 0 1 1 1 1 Tti2 family Nup160 PF11715.8 RLN49287.1 - 0.048 12.3 2.1 0.16 10.6 0.2 2.5 2 1 1 3 3 3 0 Nucleoporin Nup120/160 APH PF01636.23 RLN49287.1 - 0.051 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Arcadin_1 PF18653.1 RLN49287.1 - 0.095 12.8 0.0 0.32 11.1 0.0 1.9 1 0 0 1 1 1 0 Arcadin 1 TMCO5 PF14992.6 RLN49287.1 - 0.37 10.3 4.7 0.74 9.3 4.7 1.4 1 0 0 1 1 1 0 TMCO5 family Vps4_C PF09336.10 RLN49288.1 - 2.9e-07 30.4 0.0 4.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain SNF2_N PF00176.23 RLN49289.1 - 1.1e-60 205.2 0.0 2e-60 204.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.25 RLN49289.1 - 1.2e-07 31.4 7.0 1.2e-07 31.4 7.0 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN49289.1 - 4e-06 27.1 6.9 4e-06 27.1 6.9 2.6 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 RLN49289.1 - 6.7e-06 26.0 3.3 2.3e-05 24.3 3.3 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RLN49289.1 - 7.5e-06 25.7 8.0 2.6e-05 24.0 8.0 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN49289.1 - 1.5e-05 24.8 7.3 1.5e-05 24.8 7.3 2.7 2 0 0 2 2 2 1 zinc-RING finger domain PHD PF00628.29 RLN49289.1 - 3.7e-05 23.5 1.4 3.7e-05 23.5 1.4 4.0 4 0 0 4 4 4 1 PHD-finger zf-C3HC4_3 PF13920.6 RLN49289.1 - 0.00015 21.5 10.5 0.00015 21.5 10.5 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RLN49289.1 - 0.00063 19.9 5.9 0.0024 18.0 5.9 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RLN49289.1 - 0.0018 18.1 9.2 0.0058 16.5 9.2 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 RLN49289.1 - 0.037 13.8 6.1 0.034 13.9 4.0 2.1 2 0 0 2 2 2 0 RING-like zinc finger Methyltransf_17 PF12692.7 RLN49289.1 - 0.13 12.2 0.0 0.58 10.1 0.0 2.0 2 0 0 2 2 2 0 S-adenosyl-L-methionine methyltransferase zf-RING_4 PF14570.6 RLN49289.1 - 0.16 11.7 7.0 0.66 9.8 7.0 2.1 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DAGK_cat PF00781.24 RLN49290.1 - 5.8e-23 80.9 0.2 4e-15 55.5 0.0 2.5 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain GBP PF02263.19 RLN49292.1 - 7.4e-67 225.3 0.0 1.2e-66 224.7 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 RLN49292.1 - 2.8e-16 59.8 8.6 1e-10 41.5 0.0 2.9 2 1 0 2 2 2 2 Guanylate-binding protein, C-terminal domain PH PF00169.29 RLN49292.1 - 2e-07 31.5 0.0 4.1e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN49292.1 - 0.0047 17.3 1.3 0.071 13.5 0.2 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain Muted PF14942.6 RLN49292.1 - 1.8 8.9 5.9 5 7.4 5.9 1.7 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Nop25 PF09805.9 RLN49293.1 - 5.1e-09 36.7 28.4 5.1e-09 36.7 28.4 2.7 1 1 1 2 2 2 1 Nucleolar protein 12 (25kDa) SDA1 PF05285.12 RLN49293.1 - 0.004 16.6 21.8 0.0063 16.0 21.8 1.3 1 0 0 1 1 1 1 SDA1 Inhibitor_I71 PF12628.7 RLN49293.1 - 0.058 13.2 0.5 0.17 11.7 0.5 1.8 1 1 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor CENP-B_dimeris PF09026.10 RLN49293.1 - 0.35 11.3 22.6 1.1 9.7 1.8 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PI3K_1B_p101 PF10486.9 RLN49293.1 - 0.62 7.8 7.3 0.73 7.5 7.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nucleo_P87 PF07267.11 RLN49293.1 - 2.3 7.0 7.0 3.5 6.4 7.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RXT2_N PF08595.11 RLN49293.1 - 3 7.9 14.3 0.99 9.4 8.3 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal GREB1 PF15782.5 RLN49293.1 - 3.9 4.5 6.8 4.7 4.2 6.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NOA36 PF06524.12 RLN49293.1 - 4.2 6.6 20.5 0.18 11.1 10.4 2.2 2 0 0 2 2 2 0 NOA36 protein DUF3246 PF11596.8 RLN49293.1 - 5.3 6.4 12.5 8 5.8 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Tcp10_C PF07202.13 RLN49294.1 - 3.7e-31 108.4 0.3 3.7e-31 108.4 0.3 2.0 2 0 0 2 2 2 1 T-complex protein 10 C-terminus XhlA PF10779.9 RLN49294.1 - 3.2 8.0 7.3 7 6.9 1.0 2.6 2 0 0 2 2 2 0 Haemolysin XhlA bZIP_1 PF00170.21 RLN49294.1 - 7 6.8 13.5 0.75 9.9 2.4 2.9 2 0 0 2 2 2 0 bZIP transcription factor NDUFB10 PF10249.9 RLN49295.1 - 0.0025 18.3 0.1 0.0035 17.8 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Amidohydro_2 PF04909.14 RLN49296.1 - 5.4e-27 95.3 0.1 1.2e-26 94.2 0.1 1.6 1 1 0 1 1 1 1 Amidohydrolase Peptidase_S10 PF00450.22 RLN49297.1 - 2.6e-20 73.2 0.0 2.8e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase CBFD_NFYB_HMF PF00808.23 RLN49298.1 - 0.0024 18.1 1.0 0.0076 16.5 0.1 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Zip PF02535.22 RLN49298.1 - 1.8 7.7 5.9 2 7.6 5.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.9 RLN49298.1 - 2.6 6.5 10.2 3.2 6.2 10.2 1.0 1 0 0 1 1 1 0 Macoilin family VIT1 PF01988.19 RLN49298.1 - 9.5 6.0 6.9 11 5.8 6.6 1.4 1 1 0 1 1 1 0 VIT family Ribosomal_S19 PF00203.21 RLN49299.1 - 2.5e-32 110.6 0.1 3.6e-32 110.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 AA_permease PF00324.21 RLN49301.1 - 3.3e-10 39.1 0.4 3.8e-10 38.9 0.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 RLN49301.1 - 1.1e-07 31.0 0.8 1.2e-07 30.9 0.8 1.0 1 0 0 1 1 1 1 Amino acid permease COX1 PF00115.20 RLN49301.1 - 0.02 13.8 2.9 0.023 13.6 2.9 1.1 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I DUF2938 PF11158.8 RLN49301.1 - 0.048 13.1 2.5 0.069 12.6 2.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2938) DUF3357 PF11837.8 RLN49301.1 - 0.22 12.0 2.2 0.37 11.3 1.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Cation_ATPase_C PF00689.21 RLN49301.1 - 0.64 9.7 8.8 1.1 8.9 8.7 1.4 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus DUF4149 PF13664.6 RLN49301.1 - 3.5 8.0 9.2 12 6.2 9.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) DUF2721 PF11026.8 RLN49301.1 - 8.9 6.2 8.8 16 5.4 8.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) adh_short PF00106.25 RLN49302.1 - 2.7e-10 40.0 0.1 6.6e-06 25.7 0.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN49302.1 - 8.2e-07 28.8 1.1 0.00021 20.9 0.2 2.5 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase Spt4 PF06093.13 RLN49302.1 - 0.0046 17.0 0.4 0.015 15.4 0.4 1.9 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Epimerase PF01370.21 RLN49302.1 - 0.04 13.4 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ig_4 PF16680.5 RLN49302.1 - 0.046 14.0 0.4 0.098 12.9 0.4 1.5 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain zf-ACC PF17848.1 RLN49302.1 - 0.084 13.0 0.3 0.18 11.9 0.3 1.5 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain WH1 PF00568.23 RLN49302.1 - 0.099 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 WH1 domain DUF3915 PF13054.6 RLN49302.1 - 0.73 9.8 4.0 3.6 7.6 0.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3915) Metallophos PF00149.28 RLN49304.1 - 3.3e-17 63.7 3.7 4.3e-17 63.3 3.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RLN49304.1 - 8.2e-10 39.1 0.8 9.4e-09 35.7 0.8 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 RLN49304.1 - 0.0059 16.0 0.0 0.015 14.6 0.0 1.6 2 0 0 2 2 2 1 Metallophosphoesterase, calcineurin superfamily MFS_1 PF07690.16 RLN49305.1 - 5.8e-12 45.2 15.4 5.8e-12 45.2 15.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 RLN49305.1 - 4.3e-05 22.2 13.1 7.1e-05 21.5 13.1 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.7 RLN49305.1 - 0.015 14.2 9.9 0.0085 15.0 7.5 1.6 1 1 1 2 2 2 0 MFS_1 like family RNase_P_p30 PF01876.16 RLN49306.1 - 1.2e-22 80.4 0.0 1.5e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 LRR_9 PF14580.6 RLN49307.1 - 6.6e-56 188.5 49.5 1.2e-12 47.7 1.1 8.2 5 3 4 9 9 9 8 Leucine-rich repeat LRR_4 PF12799.7 RLN49307.1 - 1.1e-53 178.3 99.3 1.9e-06 28.1 1.8 16.7 15 2 3 18 18 18 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN49307.1 - 2.2e-28 97.8 98.1 5.5e-05 22.8 5.4 14.3 10 3 6 17 17 17 14 Leucine rich repeat LRR_6 PF13516.6 RLN49307.1 - 0.0072 16.3 65.3 1.1 9.5 0.0 17.0 18 1 1 19 19 19 4 Leucine Rich repeat ABC2_membrane_3 PF12698.7 RLN49319.1 - 3.9e-60 203.8 56.4 3.9e-39 134.7 24.3 3.3 2 2 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 RLN49319.1 - 9.6e-58 194.6 0.0 1.1e-28 100.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN49319.1 - 1.1e-21 77.9 2.6 4.8e-08 33.2 0.0 4.4 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RLN49319.1 - 1.1e-06 28.6 0.1 0.082 12.6 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 RLN49319.1 - 5.5e-06 27.0 0.2 0.0056 17.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 RLN49319.1 - 0.00018 21.4 0.3 0.013 15.4 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 RLN49319.1 - 0.0018 18.0 3.3 0.0074 16.0 0.4 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 RLN49319.1 - 0.0028 17.1 0.1 2.6 7.4 0.0 3.1 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC2_membrane PF01061.24 RLN49319.1 - 0.011 15.1 50.9 0.38 10.1 20.7 4.5 4 0 0 4 4 4 0 ABC-2 type transporter SbcCD_C PF13558.6 RLN49319.1 - 0.013 15.7 0.0 8.6 6.7 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 RLN49319.1 - 0.018 14.8 0.3 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 RLN49319.1 - 0.022 14.8 0.5 2.8 8.1 0.2 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 RLN49319.1 - 0.031 14.6 0.1 7.8 6.9 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain SRP54 PF00448.22 RLN49319.1 - 0.058 13.0 3.5 3.6 7.2 0.2 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 RLN49319.1 - 0.062 13.6 0.6 3.2 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 RLN49319.1 - 0.067 13.4 0.3 4.8 7.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 RLN49319.1 - 0.07 13.5 0.0 27 5.2 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arf PF00025.21 RLN49319.1 - 0.12 11.8 0.7 14 5.1 0.1 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.19 RLN49319.1 - 0.14 11.7 1.0 0.68 9.5 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 RLN49319.1 - 0.16 11.9 0.2 1.3 8.9 0.0 2.4 3 0 0 3 3 3 0 Rad17 P-loop domain DLIC PF05783.11 RLN49319.1 - 0.16 10.7 0.3 0.42 9.4 0.0 1.7 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) ABC2_membrane_2 PF12679.7 RLN49319.1 - 8.7 5.5 36.0 20 4.3 13.6 3.9 3 1 0 3 3 3 0 ABC-2 family transporter protein BUD22 PF09073.10 RLN49320.1 - 0.021 14.2 3.4 0.03 13.7 3.4 1.1 1 0 0 1 1 1 0 BUD22 TMEM247 PF15444.6 RLN49321.1 - 1.7 8.6 7.2 3.1 7.8 6.7 1.7 1 1 1 2 2 2 0 Transmembrane protein 247 SLX9 PF15341.6 RLN49321.1 - 2.4 8.6 10.4 0.26 11.7 4.8 2.0 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 Ints3 PF10189.9 RLN49344.1 - 9.1e-08 31.6 0.3 1.6e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 Integrator complex subunit 3 Myb_DNA-binding PF00249.31 RLN49345.1 - 3.8e-10 39.8 0.1 7.6e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN49345.1 - 0.015 15.6 1.0 0.031 14.5 1.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain JmjC PF02373.22 RLN49346.1 - 5.2e-15 55.9 0.1 7.1e-14 52.2 0.0 2.5 2 0 0 2 2 2 1 JmjC domain, hydroxylase DUF3864 PF12980.7 RLN49347.1 - 0.072 13.4 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3864) Baculo_PEP_C PF04513.12 RLN49347.1 - 0.2 11.7 0.5 6 6.9 0.0 2.5 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Arf PF00025.21 RLN49348.1 - 2e-59 200.0 0.8 1.6e-57 193.8 0.8 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 RLN49348.1 - 1.9e-11 43.7 0.1 5.6e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Roc PF08477.13 RLN49348.1 - 2.8e-11 43.7 0.6 4.4e-09 36.6 0.1 2.2 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RLN49348.1 - 2.4e-08 33.7 0.1 4e-08 33.0 0.1 1.3 1 1 1 2 2 2 1 Ras family SRPRB PF09439.10 RLN49348.1 - 1.2e-05 24.9 0.1 0.00022 20.7 0.1 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 RLN49348.1 - 3.4e-05 23.3 0.0 0.001 18.5 0.0 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RLN49348.1 - 0.00025 21.1 0.2 0.038 14.1 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN49348.1 - 0.076 12.5 1.0 7.3 6.1 0.3 2.7 1 1 1 2 2 2 0 Ferrous iron transport protein B MeaB PF03308.16 RLN49348.1 - 0.39 9.7 1.5 3.6 6.5 0.5 2.3 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GPI2 PF06432.11 RLN49349.1 - 2.8e-32 112.3 8.4 2.5e-22 79.7 6.2 2.0 1 1 1 2 2 2 2 Phosphatidylinositol N-acetylglucosaminyltransferase Col_cuticle_N PF01484.17 RLN49349.1 - 0.26 11.4 0.0 0.26 11.4 0.0 2.4 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain PRA1 PF03208.19 RLN49349.1 - 1.5 8.4 9.1 0.72 9.5 6.4 1.7 1 1 0 1 1 1 0 PRA1 family protein ANAPC4_WD40 PF12894.7 RLN49350.1 - 1.4e-14 54.2 0.0 0.00078 19.7 0.0 6.7 4 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 RLN49350.1 - 1.5e-08 34.6 25.5 0.027 14.3 0.1 9.5 7 3 2 10 10 10 3 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 RLN49350.1 - 3.4e-07 29.7 12.9 0.00022 20.4 0.8 5.6 4 2 2 6 6 6 2 Coatomer WD associated region WD40 PF00400.32 RLN49350.1 - 1.5e-06 28.8 0.3 3.2 8.8 0.0 6.1 6 0 0 6 6 6 1 WD domain, G-beta repeat PPR PF01535.20 RLN49350.1 - 0.0003 20.8 3.6 19 5.8 0.1 7.3 7 0 0 7 7 7 0 PPR repeat TPR_1 PF00515.28 RLN49350.1 - 0.0089 15.8 27.1 1 9.3 0.1 10.0 10 1 1 11 11 11 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN49350.1 - 0.018 15.1 43.3 0.053 13.6 0.4 11.6 12 0 0 12 12 11 0 Tetratricopeptide repeat TPR_7 PF13176.6 RLN49350.1 - 0.05 13.6 24.2 4.6 7.5 0.6 10.0 9 3 0 9 9 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 RLN49350.1 - 0.097 12.4 1.5 4.2 7.1 0.0 4.7 4 0 0 4 4 4 0 TPR repeat TPR_8 PF13181.6 RLN49350.1 - 0.57 10.5 17.9 39 4.8 0.1 9.1 9 1 0 9 9 9 0 Tetratricopeptide repeat MIT PF04212.18 RLN49350.1 - 0.88 9.7 4.1 26 5.0 0.1 4.5 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF410 PF04190.13 RLN49350.1 - 1.2 8.9 14.4 0.089 12.6 1.7 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF410) PPR_2 PF13041.6 RLN49350.1 - 1.6 9.0 5.7 51 4.2 0.0 5.6 5 1 1 6 6 5 0 PPR repeat family TPR_4 PF07721.14 RLN49350.1 - 2 9.3 12.7 2.7 8.9 0.1 5.8 5 0 0 5 5 3 0 Tetratricopeptide repeat DZR PF12773.7 RLN49350.1 - 2.5 8.2 8.4 7.4 6.7 8.4 1.9 1 1 0 1 1 1 0 Double zinc ribbon Sec16_C PF12931.7 RLN49350.1 - 9.7 5.7 13.5 2.9 7.5 0.1 4.9 4 2 2 6 6 6 0 Sec23-binding domain of Sec16 MMR_HSR1 PF01926.23 RLN49351.1 - 1e-15 57.8 0.0 2.1e-13 50.4 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN49351.1 - 3.7e-09 36.3 0.1 8.9e-06 25.3 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RLN49351.1 - 6.9e-06 26.1 0.1 0.00079 19.4 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 RLN49351.1 - 8e-05 22.8 0.4 8e-05 22.8 0.4 3.3 3 1 0 3 3 3 1 Dynamin family AAA_15 PF13175.6 RLN49351.1 - 0.12 12.1 2.0 0.17 11.6 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain Methyltransf_16 PF10294.9 RLN49352.1 - 3.7e-20 72.4 0.0 5.9e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 RLN49352.1 - 2.5e-09 37.0 0.1 3.6e-09 36.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 RLN49352.1 - 0.00017 21.2 0.0 0.00029 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 RLN49352.1 - 0.00019 21.1 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 RLN49352.1 - 0.0032 18.1 0.4 0.01 16.6 0.4 2.0 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 RLN49352.1 - 0.0047 16.7 0.0 0.0074 16.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 RLN49352.1 - 0.0083 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN49352.1 - 0.052 13.3 0.0 0.098 12.4 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 RLN49352.1 - 0.09 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase PF00069.25 RLN49359.1 - 2e-71 240.5 0.0 2.7e-71 240.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN49359.1 - 3.3e-39 134.7 0.0 4.8e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN49359.1 - 5.9e-07 29.0 0.1 1e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN49359.1 - 9.9e-06 24.6 0.0 1.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN49359.1 - 0.00013 21.4 0.0 0.046 13.0 0.0 2.5 2 1 0 2 2 2 2 Kinase-like F420_oxidored PF03807.17 RLN49359.1 - 0.0034 17.9 0.0 0.018 15.6 0.0 2.2 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent tRNA-synt_2 PF00152.20 RLN49360.1 - 5.4e-81 272.1 0.0 6.6e-81 271.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RLN49360.1 - 5.8e-09 35.8 0.1 1e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 RLN49360.1 - 6.2e-09 35.7 0.5 5e-05 22.9 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Renin_r PF07850.14 RLN49361.1 - 5.9e-06 26.8 0.0 1.1e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 Renin receptor-like protein Aminotran_5 PF00266.19 RLN49362.1 - 1.3e-28 100.1 0.0 1.8e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Peptidase_C48 PF02902.19 RLN49364.1 - 9.8e-09 35.4 0.0 1.3e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Aminotran_1_2 PF00155.21 RLN49364.1 - 0.18 11.0 0.2 0.3 10.2 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class I and II BK_channel_a PF03493.18 RLN49365.1 - 5.9e-29 100.1 0.0 8.5e-25 86.8 0.0 2.6 2 0 0 2 2 2 2 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 RLN49365.1 - 1e-16 61.0 6.6 1.7e-16 60.2 6.6 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RLN49365.1 - 9.9e-14 51.1 3.5 2e-13 50.1 3.5 1.5 1 0 0 1 1 1 1 Ion channel TrkA_N PF02254.18 RLN49365.1 - 0.019 15.2 0.3 0.069 13.4 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain TrkA_C PF02080.21 RLN49365.1 - 0.031 14.1 0.0 0.23 11.3 0.0 2.5 2 0 0 2 2 2 0 TrkA-C domain Sec1 PF00995.23 RLN49366.1 - 1.5e-05 24.4 0.1 0.00011 21.6 0.0 2.3 2 1 1 3 3 3 1 Sec1 family HHH_8 PF14716.6 RLN49366.1 - 0.11 12.9 0.1 0.28 11.6 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain 5_nucleotid PF05761.14 RLN49367.1 - 3.2e-42 145.0 0.0 8.3e-42 143.6 0.0 1.5 1 1 0 1 1 1 1 5' nucleotidase family HA PF03457.14 RLN49368.1 - 6.9e-27 93.6 1.9 4.3e-07 30.2 0.0 6.3 6 0 0 6 6 6 4 Helicase associated domain Ank_5 PF13857.6 RLN49368.1 - 1.2e-05 25.4 0.0 2.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN49368.1 - 0.00046 20.7 0.0 0.0012 19.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN49368.1 - 0.0012 19.2 0.0 0.47 11.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 RLN49368.1 - 0.023 15.3 0.0 0.061 13.9 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.30 RLN49368.1 - 0.09 13.3 0.3 9.8 6.8 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat Kinesin_assoc PF16183.5 RLN49368.1 - 0.17 12.0 16.8 0.075 13.2 3.9 2.7 1 1 1 2 2 2 0 Kinesin-associated Dehydratase_MU PF02288.15 RLN49368.1 - 1.7 8.5 4.5 16 5.5 1.8 3.0 3 1 0 3 3 3 0 Dehydratase medium subunit LRR_6 PF13516.6 RLN49369.1 - 9.3e-11 40.9 3.2 5.1e-05 23.0 0.1 4.6 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 RLN49369.1 - 0.0026 18.1 2.9 0.11 13.0 0.1 3.4 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN49369.1 - 0.93 9.3 8.2 0.55 10.0 0.4 3.6 4 1 0 4 4 4 0 Leucine rich repeat PX PF00787.24 RLN49370.1 - 0.036 14.0 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 PX domain Scramblase PF03803.15 RLN49371.1 - 2.7e-05 23.6 0.0 0.0049 16.2 0.0 2.9 3 0 0 3 3 3 2 Scramblase MULE PF10551.9 RLN49372.1 - 0.0001 22.6 0.1 0.053 13.9 0.0 3.1 2 1 0 2 2 2 1 MULE transposase domain SWIM PF04434.17 RLN49372.1 - 0.012 15.3 0.2 0.023 14.4 0.2 1.5 1 0 0 1 1 1 0 SWIM zinc finger 2OG-FeII_Oxy_3 PF13640.6 RLN49373.1 - 1.9e-08 35.1 0.0 3.5e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Nup192 PF11894.8 RLN49374.1 - 9.4e-54 182.2 2.7 1.5e-53 181.6 2.7 1.3 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 SRP-alpha_N PF04086.13 RLN49375.1 - 2.6 7.9 19.7 3.2 7.6 19.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SCP2 PF02036.17 RLN49376.1 - 6.1e-43 145.4 12.1 3.8e-25 88.3 1.7 3.1 3 0 0 3 3 3 3 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 RLN49376.1 - 6.6e-12 45.8 4.0 1.9e-08 34.6 0.6 2.5 2 1 1 3 3 3 2 Alkyl sulfatase C-terminal ORC5_C PF14630.6 RLN49377.1 - 4.3e-26 92.1 0.4 8.3e-26 91.1 0.4 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_22 PF13401.6 RLN49377.1 - 2.7e-05 24.5 0.1 0.00022 21.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN49377.1 - 4.3e-05 24.0 4.2 4.3e-05 24.0 4.2 2.2 2 1 0 2 2 2 1 AAA ATPase domain Pkinase PF00069.25 RLN49378.1 - 2.4e-39 135.3 0.0 6.7e-39 133.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN49378.1 - 2.1e-13 50.2 0.0 4.6e-09 35.9 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase DUF1752 PF08550.10 RLN49378.1 - 3.5e-08 33.1 1.2 8e-08 32.0 1.2 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) PH PF00169.29 RLN49378.1 - 0.0046 17.5 0.9 0.0095 16.4 0.9 1.5 1 0 0 1 1 1 1 PH domain eIF3g PF12353.8 RLN49378.1 - 0.099 13.0 0.1 0.099 13.0 0.1 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Radial_spoke PF04712.12 RLN49379.1 - 2.4e-89 300.6 0.0 1.3e-52 179.4 0.0 2.2 1 1 1 2 2 2 2 Radial spokehead-like protein pKID PF02173.17 RLN49380.1 - 0.052 13.0 0.1 0.13 11.7 0.1 1.7 1 0 0 1 1 1 0 pKID domain SH3_9 PF14604.6 RLN49382.1 - 3.4e-16 58.8 0.3 7.5e-16 57.7 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RLN49382.1 - 1.4e-12 47.0 0.0 2.8e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RLN49382.1 - 1e-10 41.1 0.0 2.6e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF3294 PF07957.11 RLN49382.1 - 0.00085 19.1 0.6 0.0021 17.8 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) UCH PF00443.29 RLN49388.1 - 4.2e-50 170.6 0.0 8.5e-50 169.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN49388.1 - 8.6e-22 78.1 0.1 3.6e-21 76.1 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Mitofilin PF09731.9 RLN49388.1 - 9.6 4.9 12.1 16 4.2 12.1 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Sugar_tr PF00083.24 RLN49390.1 - 2.9e-21 75.9 8.9 3.3e-21 75.7 8.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN49390.1 - 0.0038 16.2 1.5 0.0038 16.2 1.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DJ-1_PfpI PF01965.24 RLN49393.1 - 4.5e-29 101.4 0.0 5.6e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family CTP_transf_1 PF01148.20 RLN49394.1 - 5.3e-37 128.0 25.7 8.6e-36 124.1 15.4 2.5 2 1 0 2 2 2 2 Cytidylyltransferase family Pkinase PF00069.25 RLN49395.1 - 8.5e-60 202.3 0.0 5e-58 196.5 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN49395.1 - 2.3e-33 115.6 0.0 1.4e-31 109.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 RLN49395.1 - 6.3e-06 25.8 0.1 1.1e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kinase-like PF14531.6 RLN49395.1 - 2.4e-05 23.8 0.0 0.00025 20.5 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 RLN49395.1 - 3.2e-05 23.1 0.0 4.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 RLN49395.1 - 0.0001 22.0 0.3 0.00018 21.2 0.3 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 RLN49395.1 - 0.0014 18.6 0.7 0.031 14.2 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN49395.1 - 0.0034 16.8 0.4 0.0056 16.0 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HHA PF05321.11 RLN49395.1 - 0.016 15.5 0.0 5.8 7.3 0.0 2.6 2 0 0 2 2 2 0 Haemolysin expression modulating protein Pkinase_fungal PF17667.1 RLN49395.1 - 0.038 12.8 0.0 0.058 12.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 RLN49395.1 - 0.1 12.2 0.0 0.32 10.6 0.0 1.7 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 FtsJ PF01728.19 RLN49397.1 - 5.7e-66 222.0 0.1 7.7e-66 221.6 0.1 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 RLN49397.1 - 0.005 16.5 0.0 0.0087 15.7 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F DUF498 PF04430.14 RLN49399.1 - 1.5e-25 89.4 0.0 5.2e-24 84.4 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) SMC_Nse1 PF07574.13 RLN49400.1 - 1.8e-11 44.3 0.1 3.9e-05 23.6 0.0 3.0 2 1 0 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 RLN49400.1 - 8.9e-08 32.3 7.5 1.5e-07 31.6 7.5 1.4 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 RLN49400.1 - 6.5e-06 26.4 8.1 1.2e-05 25.5 8.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H_2 PF13832.6 RLN49400.1 - 0.0033 17.6 3.0 0.0068 16.6 3.1 1.6 1 1 0 1 1 1 1 PHD-zinc-finger like domain RQC PF09382.10 RLN49400.1 - 0.0076 16.0 0.0 0.031 14.0 0.0 1.9 2 0 0 2 2 2 1 RQC domain zf-HC5HC2H PF13771.6 RLN49400.1 - 0.01 16.1 3.4 0.01 16.1 3.4 1.8 1 1 1 2 2 2 0 PHD-like zinc-binding domain C1_1 PF00130.22 RLN49400.1 - 0.018 14.9 3.3 0.018 14.9 3.3 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.7 RLN49400.1 - 0.023 15.0 3.6 0.045 14.0 3.6 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 RLN49400.1 - 0.036 13.7 5.9 0.063 12.9 5.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 RLN49400.1 - 0.046 13.6 6.2 0.49 10.3 1.4 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.29 RLN49400.1 - 0.052 13.4 8.5 0.092 12.7 8.5 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_2 PF13923.6 RLN49400.1 - 0.078 12.8 9.6 0.1 12.4 8.3 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) C1_2 PF03107.16 RLN49400.1 - 0.2 12.0 5.9 0.47 10.8 1.0 2.3 2 0 0 2 2 2 0 C1 domain PHD_2 PF13831.6 RLN49400.1 - 1.3 8.6 5.9 2.6 7.7 5.9 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.6 RLN49400.1 - 1.9 8.4 10.7 21 5.0 0.5 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 RLN49400.1 - 2.1 8.6 10.3 26 5.1 10.3 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4 PF00097.25 RLN49400.1 - 3.7 7.5 9.0 6.7 6.7 9.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RLN49400.1 - 4.3 7.6 9.0 4.9 7.4 7.3 2.0 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING AAA_2 PF07724.14 RLN49401.1 - 3.4e-33 115.2 0.9 2.9e-25 89.4 0.0 3.4 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 RLN49401.1 - 1.3e-12 48.3 0.1 1.1e-05 25.9 0.1 3.5 3 2 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RLN49401.1 - 1.6e-06 28.1 0.2 0.00085 19.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 RLN49401.1 - 8.8e-06 25.5 0.0 0.0017 18.1 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain MCM PF00493.23 RLN49401.1 - 1e-05 24.7 0.1 0.00024 20.3 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain AAA_16 PF13191.6 RLN49401.1 - 2.6e-05 24.7 2.4 0.00023 21.6 2.4 2.4 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 RLN49401.1 - 5.3e-05 22.7 1.9 0.0062 15.9 0.0 3.5 4 1 0 4 4 4 1 Magnesium chelatase, subunit ChlI ClpB_D2-small PF10431.9 RLN49401.1 - 0.00033 20.7 0.1 0.0012 18.9 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_28 PF13521.6 RLN49401.1 - 0.00047 20.4 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 RLN49401.1 - 0.0013 18.5 0.1 0.52 10.1 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 RLN49401.1 - 0.0019 17.5 0.0 0.0041 16.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 RLN49401.1 - 0.0041 17.7 0.0 0.015 15.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 RLN49401.1 - 0.0041 16.4 0.0 0.01 15.2 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin T2SSE PF00437.20 RLN49401.1 - 0.0057 15.7 0.1 0.013 14.5 0.1 1.6 1 1 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 RLN49401.1 - 0.0073 16.6 1.8 0.015 15.5 0.0 2.5 3 1 0 3 3 2 1 AAA domain AAA_33 PF13671.6 RLN49401.1 - 0.011 15.9 0.0 0.038 14.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 RLN49401.1 - 0.011 15.6 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TsaE PF02367.17 RLN49401.1 - 0.018 15.0 0.0 0.054 13.5 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DEAD PF00270.29 RLN49401.1 - 0.018 14.8 0.2 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase G-alpha PF00503.20 RLN49401.1 - 0.039 13.1 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_7 PF12775.7 RLN49401.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region zf-CW PF07496.15 RLN49402.1 - 6.4e-09 35.7 0.3 1.6e-08 34.4 0.1 1.8 2 0 0 2 2 2 1 CW-type Zinc Finger GGACT PF06094.12 RLN49403.1 - 1.6e-14 54.5 0.1 1.9e-14 54.3 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DJ-1_PfpI PF01965.24 RLN49404.1 - 4.9e-24 85.0 0.1 5.8e-24 84.8 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 RLN49404.1 - 0.038 13.8 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Glutamine amidotransferase class-I PIH1_CS PF18201.1 RLN49405.1 - 0.0019 18.6 0.1 0.0046 17.3 0.1 1.5 1 0 0 1 1 1 1 PIH1 CS-like domain CS PF04969.16 RLN49405.1 - 0.22 12.5 0.1 0.41 11.7 0.1 1.4 1 0 0 1 1 1 0 CS domain GST_N PF02798.20 RLN49407.1 - 3.3e-23 81.8 0.0 1.8e-10 41.0 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RLN49407.1 - 2.4e-17 62.9 0.0 4.8e-11 42.7 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RLN49407.1 - 1.2e-08 35.2 0.0 0.00075 19.9 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN49407.1 - 3.5e-06 27.2 0.0 0.093 13.0 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN49407.1 - 7.8e-06 25.8 0.1 0.00033 20.6 0.0 2.8 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 RLN49407.1 - 0.008 16.9 0.0 7.4 7.4 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase N-terminal domain GST_C PF00043.25 RLN49407.1 - 0.047 13.9 0.1 0.37 11.0 0.0 2.5 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain Peptidase_M50 PF02163.22 RLN49407.1 - 0.079 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M50 7tm_3 PF00003.22 RLN49409.1 - 5.6e-39 134.3 27.2 9.6e-39 133.5 27.2 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR CytochromB561_N PF09786.9 RLN49409.1 - 0.012 14.7 0.3 0.018 14.1 0.3 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal Acyl-CoA_dh_1 PF00441.24 RLN49410.1 - 1.7e-42 145.2 1.6 2.1e-42 144.9 1.6 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RLN49410.1 - 4.1e-24 84.6 0.0 7.2e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RLN49410.1 - 1.5e-18 67.4 0.1 2e-18 67.0 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain H_PPase PF03030.16 RLN49411.1 - 9.2e-255 847.3 36.0 1.2e-254 846.9 36.0 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase zf-RING_UBOX PF13445.6 RLN49412.1 - 3.7e-05 23.6 6.6 8.1e-05 22.6 6.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RLN49412.1 - 0.00033 20.5 8.7 0.00066 19.5 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN49412.1 - 0.00037 20.3 5.7 0.00037 20.3 5.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN49412.1 - 0.00062 19.7 8.4 0.0012 18.8 8.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RLN49412.1 - 0.0065 16.3 7.9 0.012 15.4 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Siva PF05458.12 RLN49412.1 - 0.0096 15.6 2.5 0.032 13.9 2.5 1.9 1 0 0 1 1 1 1 Cd27 binding protein (Siva) zf-RING_6 PF14835.6 RLN49412.1 - 0.015 15.1 5.6 0.031 14.2 5.6 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 RLN49412.1 - 0.021 15.0 11.0 0.047 13.9 11.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Pcc1 PF09341.10 RLN49412.1 - 0.51 10.5 4.0 1 9.5 0.1 3.8 3 1 0 3 3 3 0 Transcription factor Pcc1 Prok-RING_4 PF14447.6 RLN49412.1 - 1.9 8.4 7.8 3.7 7.5 7.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 RLN49412.1 - 2.3 8.6 10.4 4.7 7.6 10.4 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_10 PF16685.5 RLN49412.1 - 2.9 8.1 8.9 7.4 6.8 8.9 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 RGS PF00615.19 RLN49416.1 - 0.032 14.5 0.1 18 5.6 0.0 2.8 2 0 0 2 2 2 0 Regulator of G protein signaling domain DNA_topoisoIV PF00521.20 RLN49417.1 - 1.2e-115 386.8 0.2 2e-115 386.1 0.2 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 RLN49417.1 - 4.2e-41 140.2 0.1 1.2e-40 138.7 0.1 1.8 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 RLN49417.1 - 2.8e-24 85.5 0.5 6.8e-24 84.3 0.5 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 RLN49417.1 - 3.2e-12 46.9 0.2 1.1e-11 45.2 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 RLN49417.1 - 6.9e-06 26.2 0.0 2.8e-05 24.3 0.0 2.1 1 0 0 1 1 1 1 Toprim domain NRho PF16733.5 RLN49417.1 - 0.16 12.0 0.4 0.5 10.4 0.4 1.8 1 0 0 1 1 1 0 Rhomboid N-terminal domain K-box PF01486.17 RLN49417.1 - 0.67 10.2 4.6 0.19 11.9 0.5 2.2 2 0 0 2 2 2 0 K-box region VWA PF00092.28 RLN49418.1 - 5.5e-11 43.0 0.0 8.8e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RLN49418.1 - 2e-09 38.0 0.0 4.1e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 RLN49418.1 - 0.0037 16.7 0.0 2.2 7.6 0.0 2.1 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein FYDLN_acid PF09538.10 RLN49419.1 - 0.077 13.7 0.3 0.077 13.7 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DZR PF12773.7 RLN49419.1 - 0.16 12.0 1.7 0.35 10.9 1.7 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2_4 PF13894.6 RLN49419.1 - 0.6 11.1 14.6 10 7.3 2.0 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 RLN49419.1 - 1.5 9.1 6.6 0.63 10.4 0.9 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Trypsin PF00089.26 RLN49492.1 - 1.2e-53 182.3 2.3 2.2e-53 181.3 2.3 1.4 1 0 0 1 1 1 1 Trypsin TFIIA PF03153.13 RLN49492.1 - 1.2 9.1 50.7 2.2 8.2 50.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Trypsin PF00089.26 RLN49494.1 - 1.3e-54 185.4 3.3 2.2e-54 184.6 3.3 1.4 1 0 0 1 1 1 1 Trypsin Peptidase_M3 PF01432.20 RLN49495.1 - 2.2e-133 445.9 0.0 4.6e-91 306.4 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M3 Peptidase_M50B PF13398.6 RLN49495.1 - 0.038 13.6 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like F-box-like PF12937.7 RLN49496.1 - 0.0087 15.9 0.1 0.0087 15.9 0.1 2.2 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 RLN49496.1 - 0.016 15.1 0.0 0.016 15.1 0.0 2.3 2 0 0 2 2 2 0 F-box domain IMUP PF15761.5 RLN49496.1 - 0.078 13.7 6.8 0.072 13.8 5.6 1.5 1 1 0 1 1 1 0 Immortalisation up-regulated protein ABC_tran PF00005.27 RLN49497.1 - 1.4e-32 113.0 0.0 2.6e-32 112.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 RLN49497.1 - 5.2e-23 82.1 9.1 8.6e-23 81.4 9.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region mTERF PF02536.14 RLN49497.1 - 1e-10 41.1 0.0 1.7e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 mTERF SMC_N PF02463.19 RLN49497.1 - 8.3e-09 35.2 0.0 1.2e-07 31.4 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain PBP1_TM PF14812.6 RLN49497.1 - 2.1e-06 28.0 2.0 2.1e-06 28.0 2.0 1.8 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_22 PF13401.6 RLN49497.1 - 0.0037 17.5 0.4 0.022 15.0 0.4 2.1 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 RLN49497.1 - 0.0069 16.2 0.1 0.022 14.6 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.6 RLN49497.1 - 0.024 15.0 0.2 0.073 13.4 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.25 RLN49497.1 - 0.05 13.3 0.0 0.097 12.3 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RsgA_GTPase PF03193.16 RLN49497.1 - 0.054 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 RLN49497.1 - 0.098 12.2 0.5 0.56 9.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain DUF3243 PF11588.8 RLN49497.1 - 0.1 12.9 0.0 0.38 11.1 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) TsaE PF02367.17 RLN49497.1 - 0.11 12.4 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 RLN49497.1 - 0.16 12.5 0.4 0.37 11.3 0.4 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RLN49497.1 - 0.24 11.2 0.6 0.54 10.0 0.6 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TFIIF_alpha PF05793.12 RLN49497.1 - 2.9 6.4 8.7 4.5 5.7 8.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HD PF01966.22 RLN49500.1 - 0.00026 21.2 0.0 0.00042 20.5 0.0 1.4 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 RLN49500.1 - 0.022 14.2 0.1 0.033 13.7 0.1 1.3 1 0 0 1 1 1 0 HDOD domain T_hemolysin PF12261.8 RLN49500.1 - 0.048 13.4 0.1 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Thermostable hemolysin KAP PF05804.12 RLN49501.1 - 2e-141 472.5 6.5 2.7e-141 472.1 6.5 1.0 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm PF00514.23 RLN49501.1 - 3e-06 27.1 0.3 0.061 13.4 0.0 4.8 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat GvpL_GvpF PF06386.11 RLN49501.1 - 0.07 13.1 2.2 0.12 12.3 0.4 2.0 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF TFIIS_M PF07500.14 RLN49502.1 - 1.4e-15 57.8 0.5 5.2e-15 55.9 0.4 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain CLU PF13236.6 RLN49503.1 - 1.4e-79 267.0 0.3 2.2e-78 263.1 0.0 2.3 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.7 RLN49503.1 - 2.7e-38 131.8 0.2 3e-37 128.4 0.0 2.7 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.6 RLN49503.1 - 1.9e-13 50.6 0.0 5.9e-13 49.0 0.0 1.9 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.6 RLN49503.1 - 5.9e-10 39.3 19.9 2.2e-07 31.0 7.7 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 RLN49503.1 - 0.0023 17.3 5.8 0.005 16.3 5.8 1.5 1 0 0 1 1 1 1 MalT-like TPR region TPR_10 PF13374.6 RLN49503.1 - 0.028 14.3 0.2 0.028 14.3 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_11 PF13086.6 RLN49503.1 - 0.031 14.1 0.5 0.031 14.1 0.5 2.3 2 0 0 2 2 2 0 AAA domain TPR_2 PF07719.17 RLN49503.1 - 0.15 12.2 8.5 1.4 9.2 0.2 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF913 PF06025.12 RLN49503.1 - 5.3 5.9 13.6 0.46 9.4 3.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.14 RLN49503.1 - 5.4 7.4 26.6 1 9.8 3.2 3.8 3 0 0 3 3 3 0 RNA polymerase III RPC4 SAPS PF04499.15 RLN49503.1 - 8.2 5.1 13.9 5.4 5.7 4.0 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein HIT PF01230.23 RLN49504.1 - 1.9e-26 92.7 0.0 2.3e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 RLN49504.1 - 1.3e-18 67.5 0.0 1.6e-18 67.2 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Sial-lect-inser PF09264.10 RLN49510.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Vibrio cholerae sialidase, lectin insertion Laminin_G_3 PF13385.6 RLN49512.1 - 1.2e-14 54.8 0.3 1.1e-09 38.6 0.2 2.4 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily TIG PF01833.24 RLN49512.1 - 1.8e-13 50.4 14.5 9e-06 25.7 0.4 5.2 4 1 0 4 4 4 3 IPT/TIG domain TIG PF01833.24 RLN49513.1 - 1.8e-166 540.7 98.1 1.9e-11 43.8 1.3 26.3 25 0 0 25 25 25 23 IPT/TIG domain TIG_plexin PF17960.1 RLN49513.1 - 1.4e-29 101.9 17.2 0.077 13.0 0.0 19.2 21 0 0 21 21 21 9 TIG domain Anth_Ig PF05587.13 RLN49513.1 - 5.9e-06 26.5 0.2 0.28 11.5 0.0 6.1 6 0 0 6 6 6 1 Anthrax receptor extracellular domain POTRA_1 PF08478.10 RLN49513.1 - 0.0048 17.2 0.0 3.1 8.1 0.0 4.8 5 0 0 5 5 5 1 POTRA domain, FtsQ-type WD40 PF00400.32 RLN49514.1 - 7.4e-25 86.7 10.0 1.8e-06 28.6 0.1 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN49514.1 - 1e-09 38.5 0.6 0.045 14.1 0.2 5.3 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN49514.1 - 0.0091 14.7 0.7 0.029 13.0 0.4 1.9 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RLN49514.1 - 0.0098 14.9 0.1 6 5.7 0.0 3.3 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Csm1_N PF18504.1 RLN49514.1 - 0.13 12.7 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain Cnn_1N PF07989.11 RLN49514.1 - 0.19 11.9 0.0 0.34 11.1 0.0 1.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 HALZ PF02183.18 RLN49514.1 - 0.29 11.4 2.4 0.68 10.2 1.7 2.0 1 1 1 2 2 2 0 Homeobox associated leucine zipper SNO PF01174.19 RLN49515.1 - 1.1e-48 165.6 0.0 1.3e-48 165.3 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 RLN49515.1 - 1.4e-08 34.5 0.0 2.1e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 RLN49515.1 - 2.2e-06 27.5 0.1 3e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 RLN49515.1 - 0.00087 19.1 0.1 0.0016 18.3 0.1 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 RLN49515.1 - 0.005 16.6 0.0 0.056 13.2 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I HEAT PF02985.22 RLN49516.1 - 1.9e-19 68.1 23.2 0.0031 17.6 0.0 9.9 10 0 0 10 10 10 6 HEAT repeat HEAT_2 PF13646.6 RLN49516.1 - 3.5e-13 49.8 15.9 0.0024 18.2 0.1 6.2 4 4 1 5 5 5 5 HEAT repeats Vac14_Fab1_bd PF12755.7 RLN49516.1 - 6.8e-10 39.4 0.2 0.021 15.4 0.0 4.6 2 2 2 4 4 4 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 RLN49516.1 - 5.8e-05 23.5 9.0 0.094 13.3 0.0 6.6 7 1 0 7 7 7 1 HEAT-like repeat CLASP_N PF12348.8 RLN49516.1 - 0.00054 19.6 0.4 1.9 8.0 0.0 3.5 2 2 1 3 3 3 2 CLASP N terminal Cnd1 PF12717.7 RLN49516.1 - 0.0022 18.0 0.9 3 7.9 0.0 3.4 1 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Ipi1_N PF12333.8 RLN49516.1 - 0.023 15.3 0.0 0.19 12.4 0.0 2.3 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation DUF1294 PF06961.13 RLN49516.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) CtaG_Cox11 PF04442.14 RLN49527.1 - 1.5e-37 128.9 1.5 1.7e-37 128.7 1.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 CBFD_NFYB_HMF PF00808.23 RLN49528.1 - 3.3e-26 91.4 0.1 4.3e-26 91.0 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 RLN49528.1 - 0.00064 20.1 0.1 0.0011 19.3 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 RLN49528.1 - 0.003 17.7 0.0 0.0036 17.4 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 RLN49528.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 1 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 RLN49528.1 - 0.014 15.8 0.5 0.46 11.0 0.1 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A TFIID-18kDa PF02269.16 RLN49528.1 - 0.054 13.5 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Kinesin PF00225.23 RLN49529.1 - 3.7e-108 361.4 0.4 3.7e-108 361.4 0.4 2.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RLN49529.1 - 2.6e-27 95.6 1.2 1.5e-26 93.1 0.0 3.0 2 0 0 2 2 2 1 Microtubule binding Filament PF00038.21 RLN49529.1 - 0.0025 17.5 38.2 0.0025 17.5 38.2 9.4 2 1 5 8 8 8 1 Intermediate filament protein DASH_Dad1 PF08649.10 RLN49529.1 - 0.14 12.4 5.8 0.79 10.0 0.1 4.2 4 0 0 4 4 4 0 DASH complex subunit Dad1 DUF4107 PF13389.6 RLN49529.1 - 7 6.8 5.8 10 6.2 0.6 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4107) GCV_H PF01597.19 RLN49530.1 - 2.1e-11 43.8 0.1 2.7e-11 43.4 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage H-protein LEAP-2 PF07359.11 RLN49530.1 - 0.17 11.8 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) PseudoU_synth_1 PF01416.20 RLN49531.1 - 1.2e-12 48.2 0.1 7.1e-10 39.3 0.0 3.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase DUF4612 PF15389.6 RLN49531.1 - 5.6 8.1 9.1 0.25 12.4 2.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4612) Stk19 PF10494.9 RLN49532.1 - 0.005 16.6 0.6 0.015 15.0 0.5 1.9 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 Pkinase PF00069.25 RLN49543.1 - 4.5e-62 209.8 0.0 5.1e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN49543.1 - 2.7e-26 92.4 0.0 3.3e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN49543.1 - 7.8e-06 25.4 0.0 1.7e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN49543.1 - 0.0028 17.0 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5383 PF17355.2 RLN49544.1 - 0.29 11.5 3.3 0.39 11.1 3.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5383) Cir_N PF10197.9 RLN49544.1 - 0.61 10.3 25.8 0.14 12.4 15.8 3.5 2 2 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR Ribosomal_L2_C PF03947.18 RLN49545.1 - 1.1e-46 158.1 1.7 1.7e-46 157.5 1.7 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 RLN49545.1 - 4.6e-17 61.7 0.1 1.2e-16 60.4 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain BT1 PF03092.16 RLN49546.1 - 9.8e-10 37.3 1.6 9.8e-10 37.3 1.6 2.6 2 1 0 2 2 2 1 BT1 family PPC PF04151.15 RLN49546.1 - 0.21 12.7 1.8 0.72 11.0 1.8 2.0 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain Dak1 PF02733.17 RLN49547.1 - 7.7e-110 366.6 5.0 1.1e-109 366.1 5.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 RLN49547.1 - 3.5e-43 147.5 4.4 7.5e-43 146.4 4.4 1.6 1 0 0 1 1 1 1 DAK2 domain DKCLD PF08068.12 RLN49548.1 - 1.3e-06 28.3 0.1 2.5e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 DKCLD (NUC011) domain S4 PF01479.25 RLN49549.1 - 5.8e-11 41.9 0.0 1.4e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 RLN49549.1 - 4.1e-08 34.0 1.8 4.1e-08 34.0 1.8 1.8 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain TelA PF05816.11 RLN49549.1 - 0.13 11.4 1.5 0.63 9.0 1.4 1.8 1 1 0 1 1 1 0 Toxic anion resistance protein (TelA) TFA2_Winged_2 PF18121.1 RLN49564.1 - 2.1e-09 36.9 0.0 6.5e-09 35.4 0.0 1.7 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 CorA PF01544.18 RLN49566.1 - 3.6e-07 29.8 9.2 2.1e-06 27.3 9.2 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein SET PF00856.28 RLN49570.1 - 3.1e-11 44.0 0.1 1.4e-10 41.9 0.1 1.9 1 1 0 1 1 1 1 SET domain bZIP_2 PF07716.15 RLN49571.1 - 0.03 14.4 6.6 0.03 14.4 6.6 2.3 2 0 0 2 2 2 0 Basic region leucine zipper TMEM192 PF14802.6 RLN49571.1 - 0.21 10.6 1.0 0.34 10.0 1.0 1.3 1 0 0 1 1 1 0 TMEM192 family bZIP_1 PF00170.21 RLN49571.1 - 1.5 8.9 17.6 0.18 11.9 9.9 2.3 1 1 1 2 2 2 0 bZIP transcription factor DUF3099 PF11298.8 RLN49574.1 - 0.072 13.2 0.4 0.45 10.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) ABC_tran PF00005.27 RLN49577.1 - 4.8e-34 117.8 0.1 5.1e-16 59.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 RLN49577.1 - 2e-33 115.6 29.0 2e-33 115.6 29.0 1.9 2 0 0 2 2 2 1 ABC-2 type transporter AAA_16 PF13191.6 RLN49577.1 - 2.4e-08 34.6 0.1 0.003 18.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 RLN49577.1 - 4e-08 32.9 2.4 0.0043 16.8 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 RLN49577.1 - 9.4e-08 32.2 0.0 0.064 13.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN49577.1 - 1.9e-07 31.1 0.6 0.0057 16.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 RLN49577.1 - 1.8e-05 25.1 0.1 0.25 11.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 RLN49577.1 - 3.8e-05 23.2 1.7 0.37 10.2 0.0 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 RLN49577.1 - 0.00011 21.8 0.1 0.052 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 RLN49577.1 - 0.00018 22.1 0.1 0.14 12.7 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RLN49577.1 - 0.00039 20.2 2.1 0.17 11.6 0.1 2.6 3 0 0 3 3 2 2 AAA domain AAA PF00004.29 RLN49577.1 - 0.00046 20.6 0.2 1.5 9.3 0.1 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RLN49577.1 - 0.00051 20.6 0.0 1.6 9.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 RLN49577.1 - 0.00086 19.1 0.0 0.62 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RLN49577.1 - 0.0012 18.1 1.0 0.15 11.3 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 RLN49577.1 - 0.0015 18.7 0.0 1.2 9.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 RLN49577.1 - 0.0024 17.9 0.9 0.48 10.5 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_5 PF07728.14 RLN49577.1 - 0.014 15.4 0.4 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 RLN49577.1 - 0.015 15.7 1.0 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 RLN49577.1 - 0.015 15.2 1.0 0.58 10.1 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 NACHT PF05729.12 RLN49577.1 - 0.019 14.9 4.0 2.6 8.0 0.7 2.8 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 RLN49577.1 - 0.021 15.1 0.8 2 8.6 0.6 2.6 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 RLN49577.1 - 0.022 15.0 0.3 4.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 RLN49577.1 - 0.027 14.9 0.2 11 6.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.13 RLN49577.1 - 0.027 13.6 0.7 0.096 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 RLN49577.1 - 0.028 14.4 0.5 1.9 8.5 0.2 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PDR_assoc PF08370.11 RLN49577.1 - 0.035 13.8 0.6 0.099 12.4 0.6 1.7 1 0 0 1 1 1 0 Plant PDR ABC transporter associated cobW PF02492.19 RLN49577.1 - 0.057 13.0 1.1 2.6 7.6 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 RLN49577.1 - 0.066 13.3 5.3 1 9.4 0.2 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Rad17 PF03215.15 RLN49577.1 - 0.099 12.5 0.1 2 8.3 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain PduV-EutP PF10662.9 RLN49577.1 - 0.11 12.3 1.2 4.3 7.1 0.3 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DnaB_C PF03796.15 RLN49577.1 - 0.19 11.0 0.1 3.1 7.1 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain G-alpha PF00503.20 RLN49577.1 - 0.25 10.5 0.0 5.1 6.2 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit PDR_CDR PF06422.12 RLN49577.1 - 0.32 10.9 2.4 2.7 8.0 0.7 2.5 2 0 0 2 2 2 0 CDR ABC transporter NB-ARC PF00931.22 RLN49577.1 - 0.46 9.6 2.2 9.6 5.3 0.6 2.4 2 0 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 RLN49577.1 - 0.87 8.9 3.3 5.2 6.3 0.3 2.8 2 1 1 3 3 3 0 KaiC ABC2_membrane_3 PF12698.7 RLN49577.1 - 6.5 5.8 32.8 0.012 14.7 21.3 2.0 2 0 0 2 2 1 0 ABC-2 family transporter protein Sugar_tr PF00083.24 RLN49587.1 - 8.2e-25 87.6 21.7 2e-24 86.3 21.7 1.7 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN49587.1 - 2.4e-10 39.9 15.6 2.4e-10 39.9 15.6 3.8 1 1 3 4 4 4 1 Major Facilitator Superfamily PgaD PF13994.6 RLN49587.1 - 7.9 6.5 9.1 0.42 10.7 0.3 2.8 3 0 0 3 3 3 0 PgaD-like protein HECT PF00632.25 RLN49588.1 - 1.4e-41 143.0 0.0 1.6e-41 142.8 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ABC_tran PF00005.27 RLN49601.1 - 2.9e-29 102.4 0.0 4.3e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN49601.1 - 2.3e-05 24.0 0.0 0.0058 16.1 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 RLN49601.1 - 0.00099 19.3 0.0 0.0055 16.8 0.0 2.1 2 0 0 2 2 2 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 RLN49601.1 - 0.001 19.1 0.0 0.0026 17.8 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 RLN49601.1 - 0.0015 18.3 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 RLN49601.1 - 0.0043 16.9 0.2 0.039 13.7 0.2 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4523 PF15023.6 RLN49601.1 - 0.014 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) AAA_21 PF13304.6 RLN49601.1 - 0.016 15.0 0.1 0.35 10.6 0.0 2.1 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN49601.1 - 0.078 12.9 0.3 1 9.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 RLN49601.1 - 0.089 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN49601.1 - 0.094 13.2 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain SIR2 PF02146.17 RLN49604.1 - 1.6e-42 145.4 0.0 3.8e-42 144.2 0.0 1.6 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 RLN49604.1 - 0.0018 18.0 0.0 0.58 9.9 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 RLN49604.1 - 0.0072 16.1 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF592) UvrC_HhH_N PF08459.11 RLN49604.1 - 0.039 13.9 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal Pkinase_Tyr PF07714.17 RLN49605.1 - 3.2e-42 144.6 0.0 5.7e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN49605.1 - 7.6e-41 140.2 0.0 1.4e-40 139.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 RLN49605.1 - 0.0011 18.4 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_8 PF12780.7 RLN49605.1 - 0.11 11.8 0.0 0.27 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 SprA-related PF12118.8 RLN49606.1 - 0.064 12.4 19.2 0.086 12.0 19.2 1.1 1 0 0 1 1 1 0 SprA-related family DUF2685 PF10886.8 RLN49606.1 - 0.11 12.8 0.2 0.27 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2685) CDC27 PF09507.10 RLN49606.1 - 0.29 10.5 25.6 0.36 10.2 25.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nucleo_P87 PF07267.11 RLN49606.1 - 1.1 8.0 15.8 1.3 7.8 15.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PPP4R2 PF09184.11 RLN49606.1 - 7.4 6.1 32.4 11 5.5 32.4 1.2 1 0 0 1 1 1 0 PPP4R2 Methyltransf_31 PF13847.6 RLN49611.1 - 2.7e-29 101.9 0.0 5e-29 101.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN49611.1 - 3.7e-18 66.0 0.0 6.7e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN49611.1 - 6.3e-17 62.0 0.0 1.1e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN49611.1 - 1.6e-11 44.3 0.0 2.3e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN49611.1 - 4.5e-11 43.4 0.0 7.9e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN49611.1 - 4.6e-10 39.2 0.0 8.3e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 RLN49611.1 - 2e-05 24.5 0.0 3.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 RLN49611.1 - 0.00021 20.8 0.0 0.00033 20.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 RLN49611.1 - 0.0014 18.6 0.1 0.018 14.9 0.0 2.3 3 0 0 3 3 3 1 Hypothetical methyltransferase MTS PF05175.14 RLN49611.1 - 0.011 15.2 0.0 0.025 14.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_29 PF03141.16 RLN49611.1 - 0.013 14.1 0.0 0.025 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase TehB PF03848.14 RLN49611.1 - 0.014 14.8 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 RLN49611.1 - 0.022 14.2 0.0 0.57 9.6 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase CMAS PF02353.20 RLN49611.1 - 0.025 13.9 0.1 0.044 13.1 0.1 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase CheR PF01739.18 RLN49611.1 - 0.066 12.7 0.0 2.7 7.4 0.0 2.3 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain LRR_4 PF12799.7 RLN49612.1 - 8.4e-09 35.6 7.1 0.0089 16.4 0.2 5.3 5 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN49612.1 - 2.8e-05 23.8 11.3 0.13 12.1 0.0 5.7 4 2 1 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 RLN49612.1 - 4.4e-05 23.4 10.0 6.6 7.7 0.0 6.7 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 RLN49612.1 - 0.072 13.2 16.0 7 7.0 0.0 6.6 8 0 0 8 8 8 0 Leucine Rich repeat MAT1 PF06391.13 RLN49613.1 - 4.9e-23 82.0 12.9 7.2e-23 81.5 12.9 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_2 PF13639.6 RLN49613.1 - 2.3e-05 24.7 11.2 3.8e-05 23.9 11.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RLN49613.1 - 0.00011 22.0 13.0 0.00018 21.3 13.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 RLN49613.1 - 0.00059 19.7 6.8 0.00059 19.7 6.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN49613.1 - 0.001 19.0 14.2 0.0026 17.7 14.3 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RLN49613.1 - 0.0015 18.3 14.0 0.0035 17.1 14.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RLN49613.1 - 0.0016 18.5 3.1 0.0016 18.5 3.1 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RLN49613.1 - 0.0017 18.2 10.1 0.0031 17.3 10.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 RLN49613.1 - 0.0055 17.0 8.8 0.011 16.1 8.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RLN49613.1 - 0.0073 16.3 7.5 0.014 15.4 7.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger DNA_pol3_chi PF04364.13 RLN49613.1 - 0.039 14.1 1.0 0.13 12.4 0.1 2.1 1 1 1 2 2 2 0 DNA polymerase III chi subunit, HolC zf-ANAPC11 PF12861.7 RLN49613.1 - 0.062 13.3 3.8 0.11 12.6 3.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 RLN49613.1 - 2 8.5 10.1 56 3.9 10.7 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.6 RLN49613.1 - 3.9 7.3 12.6 41 4.1 13.1 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain IBR PF01485.21 RLN49613.1 - 4.2 7.7 10.9 8.2 6.7 8.6 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain FHA PF00498.26 RLN49615.1 - 5.1e-08 33.2 0.1 1e-07 32.2 0.1 1.6 1 0 0 1 1 1 1 FHA domain CHAT PF12770.7 RLN49615.1 - 5.6e-07 29.3 0.0 1e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 CHAT domain NACHT PF05729.12 RLN49615.1 - 1.4e-06 28.3 0.2 4.9e-06 26.6 0.2 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 RLN49615.1 - 0.00092 19.6 0.2 0.0039 17.6 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RLN49615.1 - 0.001 19.3 0.9 0.0036 17.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RLN49615.1 - 0.0042 17.5 0.0 0.0083 16.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 RLN49615.1 - 0.0054 16.7 0.0 0.0098 15.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain TIP49 PF06068.13 RLN49615.1 - 0.13 11.5 0.1 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain HisKA_7TM PF16927.5 RLN49616.1 - 0.12 12.4 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 N-terminal 7TM region of histidine kinase SF3b1 PF08920.10 RLN49617.1 - 1.4e-39 135.2 27.2 8.7e-32 110.1 27.2 4.5 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 RLN49617.1 - 6.9e-09 36.0 3.6 0.088 13.3 0.0 7.3 7 1 0 7 7 7 2 HEAT-like repeat HEAT PF02985.22 RLN49617.1 - 5.1e-08 32.5 6.5 4.5 7.8 0.1 9.2 10 0 0 10 10 10 1 HEAT repeat HEAT_2 PF13646.6 RLN49617.1 - 7.2e-08 32.7 5.7 0.11 12.9 0.0 6.9 6 2 2 8 8 8 3 HEAT repeats UME PF08064.13 RLN49617.1 - 0.0037 17.1 0.7 29 4.6 0.0 5.8 6 1 1 7 7 7 0 UME (NUC010) domain RTP1_C1 PF10363.9 RLN49617.1 - 0.0047 17.1 0.8 3.2 8.0 0.0 4.2 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 RLN49617.1 - 0.013 15.5 0.0 9.9 6.4 0.0 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.10 RLN49617.1 - 0.028 14.2 0.1 0.42 10.4 0.0 2.7 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) NUC173 PF08161.12 RLN49617.1 - 0.056 13.1 0.4 4.7 6.8 0.0 4.2 4 2 1 5 5 5 0 NUC173 domain UNC45-central PF11701.8 RLN49617.1 - 0.091 12.7 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central DivIC PF04977.15 RLN49617.1 - 7.5 6.4 6.6 17 5.3 6.6 1.5 1 0 0 1 1 1 0 Septum formation initiator Pkinase PF00069.25 RLN49620.1 - 5.7e-50 170.1 0.0 8.8e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN49620.1 - 2.4e-41 141.7 0.0 3.6e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SKG6 PF08693.10 RLN49620.1 - 0.00019 20.8 3.1 0.00059 19.2 3.1 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 RLN49620.1 - 0.0011 18.9 0.1 0.0028 17.6 0.1 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF1180 PF06679.12 RLN49620.1 - 0.0012 19.3 1.0 0.0028 18.1 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Amnionless PF14828.6 RLN49620.1 - 0.0032 16.3 0.1 0.0054 15.6 0.1 1.3 1 0 0 1 1 1 1 Amnionless Mid2 PF04478.12 RLN49620.1 - 0.004 17.0 0.2 0.0081 16.0 0.2 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Rax2 PF12768.7 RLN49620.1 - 0.0041 16.6 0.2 0.0085 15.6 0.2 1.5 1 0 0 1 1 1 1 Cortical protein marker for cell polarity DUF202 PF02656.15 RLN49620.1 - 0.0065 16.9 1.4 0.022 15.2 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF202) TMEM132D_C PF15706.5 RLN49620.1 - 0.0085 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term EphA2_TM PF14575.6 RLN49620.1 - 0.014 16.3 0.1 0.043 14.7 0.1 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 RLN49620.1 - 0.024 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Protocadherin LRR_4 PF12799.7 RLN49620.1 - 0.032 14.6 10.4 0.94 10.0 0.5 4.1 3 2 2 5 5 4 0 Leucine Rich repeats (2 copies) RIFIN PF02009.16 RLN49620.1 - 0.093 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Rifin Podoplanin PF05808.11 RLN49620.1 - 1.2 9.2 11.8 0.17 12.0 5.7 2.3 2 0 0 2 2 2 0 Podoplanin Pkinase PF00069.25 RLN49621.1 - 1.4e-50 172.1 0.0 2.4e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN49621.1 - 8.2e-43 146.5 0.0 1.1e-42 146.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 RLN49621.1 - 4.9e-08 32.6 4.5 0.0002 21.1 1.4 3.0 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 RLN49621.1 - 5.8e-06 26.6 10.7 0.00067 20.0 0.7 4.2 2 2 1 4 4 4 1 Leucine Rich repeats (2 copies) TMEM154 PF15102.6 RLN49621.1 - 4.7e-05 23.3 0.2 4.7e-05 23.3 0.2 1.9 2 0 0 2 2 2 1 TMEM154 protein family Protocadherin PF08374.11 RLN49621.1 - 5.8e-05 23.2 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 Protocadherin EphA2_TM PF14575.6 RLN49621.1 - 0.0011 19.8 0.0 0.004 18.0 0.0 1.9 2 0 0 2 2 1 1 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 RLN49621.1 - 0.0032 17.5 1.7 0.0074 16.3 1.7 1.6 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment Orf78 PF06024.12 RLN49621.1 - 0.0034 17.7 0.0 0.0065 16.8 0.0 1.4 1 0 0 1 1 1 1 Orf78 (ac78) Mid2 PF04478.12 RLN49621.1 - 0.0054 16.6 0.3 0.011 15.6 0.3 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 RLN49621.1 - 0.0078 16.0 1.3 0.018 14.8 1.3 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Chordopox_A13L PF05961.11 RLN49621.1 - 0.0078 16.4 0.1 0.018 15.3 0.1 1.6 1 0 0 1 1 1 1 Chordopoxvirus A13L protein Ly49 PF08391.10 RLN49621.1 - 0.012 16.0 0.1 0.027 14.8 0.1 1.5 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Vpu PF00558.19 RLN49621.1 - 0.013 15.3 0.7 0.027 14.2 0.7 1.5 1 0 0 1 1 1 0 Vpu protein DUF202 PF02656.15 RLN49621.1 - 0.017 15.6 0.0 0.052 14.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF202) DUF5385 PF17359.2 RLN49621.1 - 0.017 14.7 0.2 0.026 14.1 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF5305 PF17231.2 RLN49621.1 - 0.019 14.4 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Saf_2TM PF18303.1 RLN49621.1 - 0.022 14.3 0.2 0.058 13.0 0.2 1.6 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain LRR_1 PF00560.33 RLN49621.1 - 0.031 14.8 2.4 0.72 10.6 0.1 3.6 3 0 0 3 3 2 0 Leucine Rich Repeat RIFIN PF02009.16 RLN49621.1 - 0.034 14.1 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 Rifin Shisa PF13908.6 RLN49621.1 - 0.046 14.0 0.2 0.089 13.0 0.2 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Amnionless PF14828.6 RLN49621.1 - 0.052 12.4 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 Amnionless SKG6 PF08693.10 RLN49621.1 - 0.057 12.8 7.8 0.15 11.5 7.8 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM100 PF16311.5 RLN49621.1 - 0.082 12.5 0.2 0.23 11.1 0.2 1.7 1 0 0 1 1 1 0 Transmembrane protein 100 BatD PF13584.6 RLN49621.1 - 0.085 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Oxygen tolerance SR-25 PF10500.9 RLN49621.1 - 0.17 11.4 4.5 0.34 10.5 4.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FNIP PF05725.12 RLN49621.1 - 0.22 11.7 0.5 13 6.0 0.0 2.6 2 0 0 2 2 2 0 FNIP Repeat FeoB_associated PF12669.7 RLN49621.1 - 0.34 11.4 1.7 0.73 10.3 1.7 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF1180 PF06679.12 RLN49621.1 - 1.6 9.1 3.7 0.51 10.7 0.6 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF1180) Striatin PF08232.12 RLN49622.1 - 0.12 12.9 3.9 0.26 11.9 0.1 2.1 2 0 0 2 2 2 0 Striatin family DSHCT PF08148.12 RLN49623.1 - 4e-53 179.4 2.0 8.6e-53 178.4 0.5 2.2 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 RLN49623.1 - 8.9e-26 91.4 0.0 2.1e-25 90.2 0.0 1.7 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 RLN49623.1 - 2.9e-16 59.7 0.3 3.7e-15 56.1 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN49623.1 - 5.4e-06 26.7 0.0 1.6e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ski2_N PF17911.1 RLN49623.1 - 0.025 14.4 0.1 0.055 13.3 0.1 1.5 1 0 0 1 1 1 0 Ski2 N-terminal region AAA_22 PF13401.6 RLN49623.1 - 0.075 13.3 0.0 0.31 11.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 RLN49623.1 - 0.093 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein EF-hand_1 PF00036.32 RLN49624.1 - 3.2e-13 48.2 2.5 7.1e-06 25.2 0.3 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RLN49624.1 - 1.3e-11 44.7 0.9 4.1e-11 43.2 0.4 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN49624.1 - 3e-09 36.1 0.1 0.00078 19.2 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RLN49624.1 - 2e-07 30.2 1.6 0.011 15.2 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 RLN49624.1 - 2.7e-05 23.9 2.4 0.0046 16.8 0.2 3.0 3 0 0 3 3 3 2 EF-hand domain pair FUSC PF04632.12 RLN49624.1 - 0.027 13.0 7.8 0.065 11.8 7.2 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family RRM_1 PF00076.22 RLN49625.1 - 1.4e-08 34.4 0.0 3.7e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Plant_tran PF04827.14 RLN49625.1 - 0.022 14.4 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 Plant transposon protein EF-hand_7 PF13499.6 RLN49626.1 - 9.4e-08 32.4 0.1 2.9e-07 30.8 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN49626.1 - 0.00019 20.7 0.2 0.0043 16.5 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RLN49626.1 - 0.00045 19.9 0.1 0.011 15.6 0.0 2.9 2 1 0 2 2 2 1 EF-hand domain K-box PF01486.17 RLN49626.1 - 0.015 15.4 0.8 0.053 13.7 0.8 2.0 1 0 0 1 1 1 0 K-box region Mntp PF02659.15 RLN49626.1 - 0.24 11.2 2.6 0.67 9.7 2.6 1.7 1 0 0 1 1 1 0 Putative manganese efflux pump FUSC_2 PF13515.6 RLN49626.1 - 2.2 8.4 11.9 4.5 7.4 10.5 2.2 1 1 1 2 2 2 0 Fusaric acid resistance protein-like DUF962 PF06127.11 RLN49628.1 - 1.1e-25 89.5 0.2 2.6e-25 88.3 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF962 PF06127.11 RLN49629.1 - 1.4e-19 70.0 3.0 2.1e-19 69.4 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Glyco_hydro_28 PF00295.17 RLN49637.1 - 7e-13 48.3 0.1 8.3e-13 48.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_28 PF00295.17 RLN49638.1 - 8.3e-13 48.1 0.1 9.9e-13 47.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 PKD_channel PF08016.12 RLN49641.1 - 1.2e-15 57.2 16.0 2.7e-12 46.1 7.0 3.5 3 1 1 4 4 4 3 Polycystin cation channel Ion_trans PF00520.31 RLN49641.1 - 2.7 7.2 15.4 0.066 12.4 8.1 1.8 2 1 0 2 2 2 0 Ion transport protein ABC_tran PF00005.27 RLN49642.1 - 1e-16 61.7 0.0 1.6e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN49642.1 - 8.7e-06 25.3 1.2 4.7e-05 22.9 1.2 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RLN49642.1 - 1.1e-05 25.5 2.3 0.0028 17.5 0.5 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 RLN49642.1 - 1.4e-05 24.8 0.2 2.2e-05 24.2 0.2 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 RLN49642.1 - 0.0012 18.6 1.8 0.0049 16.6 1.8 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 RLN49642.1 - 0.0033 16.7 0.1 0.005 16.1 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 RLN49642.1 - 0.0045 16.7 0.2 0.0098 15.6 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP-synt_ab PF00006.25 RLN49642.1 - 0.0096 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_16 PF13191.6 RLN49642.1 - 0.016 15.6 0.6 0.027 14.8 0.6 1.5 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 RLN49642.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 RLN49642.1 - 0.12 12.7 0.5 0.21 11.8 0.5 1.6 1 1 0 1 1 1 0 AAA domain CobA_CobO_BtuR PF02572.15 RLN49642.1 - 0.32 11.2 1.8 1.2 9.4 1.8 1.9 1 1 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Peptidase_M16_M PF16187.5 RLN49644.1 - 0.13 11.5 0.0 0.14 11.4 0.0 1.0 1 0 0 1 1 1 0 Middle or third domain of peptidase_M16 CCT PF06203.14 RLN49645.1 - 3.8e-15 55.7 6.8 4.4e-15 55.5 6.8 1.1 1 0 0 1 1 1 1 CCT motif Yae1_N PF09811.9 RLN49646.1 - 0.065 12.9 0.4 0.097 12.4 0.4 1.3 1 0 0 1 1 1 0 Essential protein Yae1, N terminal FAM176 PF14851.6 RLN49648.1 - 0.055 13.1 0.8 0.096 12.3 0.4 1.7 1 1 1 2 2 2 0 FAM176 family YL1 PF05764.13 RLN49648.1 - 0.81 9.8 12.4 1.1 9.3 12.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Stm1_N PF09598.10 RLN49648.1 - 6.5 7.7 20.1 13 6.8 11.1 2.9 2 1 0 2 2 2 0 Stm1 MULE PF10551.9 RLN49649.1 - 2.1e-09 37.6 0.0 5.3e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_4 PF13359.6 RLN49680.1 - 0.0011 18.7 0.0 0.0039 16.9 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HEAT PF02985.22 RLN49686.1 - 5.9e-14 51.0 7.3 0.81 10.1 0.0 10.6 11 0 0 11 11 11 4 HEAT repeat HEAT_EZ PF13513.6 RLN49686.1 - 2.8e-11 43.7 8.6 8.3e-09 35.8 0.0 6.9 7 0 0 7 7 7 1 HEAT-like repeat HEAT_2 PF13646.6 RLN49686.1 - 1.4e-05 25.4 10.5 0.66 10.4 0.1 6.7 4 2 4 8 8 7 3 HEAT repeats IBN_N PF03810.19 RLN49686.1 - 2.3e-05 24.2 0.7 0.012 15.5 0.0 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 RLN49686.1 - 0.0002 21.9 0.8 3.4 8.3 0.0 4.6 3 1 2 5 5 5 2 Vacuolar 14 Fab1-binding region Arm PF00514.23 RLN49686.1 - 0.00088 19.2 4.5 5.7 7.1 0.0 6.4 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 RLN49686.1 - 0.033 13.7 0.0 0.92 9.0 0.0 3.3 3 0 0 3 3 3 0 CLASP N terminal DUF577 PF04510.12 RLN49686.1 - 0.037 13.9 0.4 0.15 11.9 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF577) RIX1 PF08167.12 RLN49686.1 - 0.043 13.6 0.0 1.8 8.3 0.0 3.5 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis DUF1041 PF06292.17 RLN49686.1 - 0.054 13.9 0.1 0.32 11.4 0.1 2.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) Ecm29 PF13001.7 RLN49686.1 - 0.062 12.0 0.2 4.7 5.8 0.0 2.7 2 1 0 2 2 2 0 Proteasome stabiliser RRM_1 PF00076.22 RLN49691.1 - 1.4e-13 50.5 0.0 2e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RVT_3 PF13456.6 RLN49698.1 - 0.00041 20.1 0.2 9.4 6.1 0.2 4.7 4 0 0 4 4 4 1 Reverse transcriptase-like CALM_bind PF16025.5 RLN49698.1 - 0.085 13.3 33.5 0.13 12.7 2.3 5.4 4 2 1 5 5 5 0 Calcium-dependent calmodulin binding DASH_Dam1 PF08653.10 RLN49698.1 - 0.11 12.4 0.3 9.9 6.0 0.0 2.8 2 0 0 2 2 2 0 DASH complex subunit Dam1 Phage_integr_3 PF16795.5 RLN49698.1 - 0.12 12.3 0.0 24 4.8 0.0 2.8 2 0 0 2 2 2 0 Archaeal phage integrase Acyltransferase PF01553.21 RLN49698.1 - 0.12 12.0 0.0 21 4.7 0.0 2.4 2 0 0 2 2 2 0 Acyltransferase ABC_trans_N PF14510.6 RLN49698.1 - 0.5 11.0 12.4 47 4.7 0.0 5.0 4 0 0 4 4 4 0 ABC-transporter N-terminal ADAM_CR PF08516.12 RLN49698.1 - 2.2 8.7 6.7 9 6.7 0.1 3.5 4 0 0 4 4 4 0 ADAM cysteine-rich DUF5320 PF17253.2 RLN49698.1 - 6 8.0 12.9 5.3 8.2 0.2 3.8 3 0 0 3 3 3 0 Family of unknown function (DUF5320) DUF1663 PF07909.11 RLN49700.1 - 0.0095 14.7 0.1 0.17 10.6 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1663) MIP PF00230.20 RLN49701.1 - 7.5e-41 140.3 10.5 9.7e-41 139.9 10.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF3573 PF12097.8 RLN49703.1 - 0.0083 15.0 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3573) Ribosomal_S8e PF01201.22 RLN49703.1 - 0.18 12.0 0.8 0.5 10.5 0.8 1.7 1 0 0 1 1 1 0 Ribosomal protein S8e NUC PF18510.1 RLN49703.1 - 0.21 12.0 0.7 5.4 7.4 0.1 2.4 2 0 0 2 2 2 0 Nuclease domain bZIP_1 PF00170.21 RLN49703.1 - 0.46 10.6 15.1 2.2 8.4 4.9 2.7 2 0 0 2 2 2 0 bZIP transcription factor YPEB PF14620.6 RLN49703.1 - 2.3 7.5 10.4 0.13 11.6 1.4 2.1 2 0 0 2 2 2 0 YpeB sporulation CALM_bind PF16025.5 RLN49704.1 - 0.0082 16.6 6.6 0.024 15.1 6.6 1.9 1 0 0 1 1 1 1 Calcium-dependent calmodulin binding AROS PF15684.5 RLN49704.1 - 0.12 12.9 4.8 0.21 12.2 4.0 1.8 1 1 0 1 1 1 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 PspB PF06667.12 RLN49704.1 - 1.9 8.6 4.3 0.95 9.6 0.8 2.2 2 0 0 2 2 2 0 Phage shock protein B SRP72 PF08492.12 RLN49705.1 - 0.011 16.2 3.3 0.011 16.1 0.8 2.1 2 0 0 2 2 2 0 SRP72 RNA-binding domain Trimer_CC PF08954.11 RLN49705.1 - 0.1 12.1 6.7 0.086 12.4 0.9 2.6 2 0 0 2 2 2 0 Trimerisation motif DUF4404 PF14357.6 RLN49705.1 - 0.12 13.0 3.0 1 10.0 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) COG2 PF06148.11 RLN49705.1 - 0.54 10.3 3.6 3.2 7.9 0.0 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Lzipper-MIP1 PF14389.6 RLN49705.1 - 0.74 10.2 5.9 1.7 9.0 0.6 2.3 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Macoilin PF09726.9 RLN49705.1 - 7.2 5.0 13.2 12 4.3 13.2 1.4 1 1 0 1 1 1 0 Macoilin family Med10 PF09748.9 RLN49706.1 - 2.1e-09 37.4 0.0 3.1e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3701 PF12482.8 RLN49706.1 - 0.071 13.2 0.0 7.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Phage integrase protein Arf PF00025.21 RLN49706.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family CCT PF06203.14 RLN49710.1 - 5.6e-15 55.1 12.5 8.8e-15 54.5 12.5 1.3 1 0 0 1 1 1 1 CCT motif Aldedh PF00171.22 RLN49726.1 - 2.3e-142 474.8 0.2 2.8e-142 474.5 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_C PF05199.13 RLN49726.1 - 6.6e-15 55.9 0.1 1.4e-14 54.8 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DUF1487 PF07368.11 RLN49726.1 - 0.0019 17.7 0.0 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) ABC_tran PF00005.27 RLN49740.1 - 2.7e-07 31.2 0.1 5.7e-07 30.1 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 RLN49740.1 - 0.00043 20.0 0.2 0.00074 19.2 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN49740.1 - 0.0026 18.1 0.3 0.005 17.3 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 RLN49740.1 - 0.0037 17.2 0.0 0.0044 16.9 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 RLN49740.1 - 0.0091 16.3 0.1 0.022 15.0 0.1 1.7 1 1 1 2 2 2 1 AAA domain DUF87 PF01935.17 RLN49740.1 - 0.022 14.8 0.1 0.046 13.8 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain Zeta_toxin PF06414.12 RLN49740.1 - 0.045 13.0 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.13 RLN49740.1 - 0.06 12.5 0.0 0.067 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 RLN49740.1 - 0.079 13.0 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.7 RLN49740.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain adh_short PF00106.25 RLN49744.1 - 9.5e-31 106.8 0.0 1.5e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN49744.1 - 4.9e-22 78.6 0.1 8.3e-22 77.9 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HTH_Tnp_Tc5 PF03221.16 RLN49744.1 - 9.4e-10 38.4 0.0 2.1e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain KR PF08659.10 RLN49744.1 - 6.2e-06 26.2 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN49744.1 - 0.0049 16.4 0.0 0.0069 15.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 RLN49744.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Ank_2 PF12796.7 RLN49768.1 - 7.7e-73 241.1 15.4 2e-19 70.0 0.1 4.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN49768.1 - 1.3e-54 181.9 11.9 1.3e-11 44.8 0.3 6.6 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 RLN49768.1 - 2.1e-48 160.7 18.6 6.2e-08 32.7 0.1 9.3 8 1 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.6 RLN49768.1 - 1.2e-46 151.2 3.3 0.00016 21.9 0.0 8.5 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 RLN49768.1 - 3.4e-43 145.1 16.5 7.2e-08 32.6 0.1 7.9 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 RLN49768.1 - 0.087 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 RLN49768.1 - 0.13 11.6 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain CK_II_beta PF01214.18 RLN49769.1 - 1.7e-20 73.6 0.2 5.6e-11 42.6 0.1 2.3 1 1 1 2 2 2 2 Casein kinase II regulatory subunit Mak10 PF04112.13 RLN49770.1 - 2.9e-29 101.7 0.1 1.3e-28 99.6 0.0 2.1 2 1 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase AP3D1 PF06375.11 RLN49770.1 - 0.081 13.2 3.4 2.8 8.2 0.0 2.3 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 CAP_N PF01213.19 RLN49770.1 - 0.42 10.1 9.1 1 8.7 3.3 2.7 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal MAP17 PF15807.5 RLN49771.1 - 0.00052 20.2 0.0 0.00061 20.0 0.0 1.1 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Phage_Gp23 PF10669.9 RLN49771.1 - 0.0043 17.4 0.1 0.0057 17.0 0.1 1.1 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) DsbD_2 PF13386.6 RLN49771.1 - 0.0083 16.1 0.0 0.0095 15.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region OSTbeta PF15048.6 RLN49771.1 - 0.024 14.7 0.1 0.03 14.4 0.1 1.1 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF5437 PF17505.2 RLN49771.1 - 0.045 13.8 0.3 0.076 13.1 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5437) ETRAMP PF09716.10 RLN49771.1 - 0.049 13.7 0.1 0.064 13.3 0.1 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DcuC PF03606.15 RLN49771.1 - 0.057 11.9 0.1 0.07 11.6 0.1 1.0 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier SID-1_RNA_chan PF13965.6 RLN49771.1 - 0.12 10.8 0.0 0.12 10.7 0.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ABC_membrane PF00664.23 RLN49772.1 - 1.5e-08 34.7 0.4 1.8e-08 34.4 0.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF981 PF06168.11 RLN49772.1 - 0.011 15.6 0.1 0.015 15.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF981) Aldo_ket_red PF00248.21 RLN49773.1 - 1.6e-67 227.8 0.0 1.8e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GRIN_C PF15235.6 RLN49773.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 G protein-regulated inducer of neurite outgrowth C-terminus Glutaredoxin PF00462.24 RLN49775.1 - 1.3e-17 63.8 0.0 2.9e-08 33.8 0.0 2.2 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin_2 PF13098.6 RLN49775.1 - 0.0027 18.1 0.2 0.0029 18.0 0.2 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain GST_N_3 PF13417.6 RLN49775.1 - 0.006 17.0 0.0 0.027 14.9 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN49775.1 - 0.016 15.5 0.0 0.11 12.8 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_4 PF13462.6 RLN49775.1 - 0.13 12.4 0.0 3.5 7.8 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin PH PF00169.29 RLN49792.1 - 1.1e-05 25.9 0.0 2.8e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 PH domain SAICAR_synt PF01259.18 RLN49800.1 - 8.2e-79 264.8 0.0 1.1e-78 264.4 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Mg_trans_NIPA PF05653.14 RLN49801.1 - 2e-40 138.7 14.7 1.3e-39 136.0 14.7 1.9 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 RLN49801.1 - 1.3e-05 25.4 4.6 1.3e-05 25.4 4.6 3.4 2 2 1 3 3 3 1 EamA-like transporter family TMEM234 PF10639.9 RLN49801.1 - 0.00039 20.4 1.8 0.00044 20.3 0.2 2.0 2 0 0 2 2 2 1 Putative transmembrane family 234 DEC-1_N PF04625.13 RLN49802.1 - 0.14 11.1 4.8 0.19 10.7 4.1 1.5 1 1 1 2 2 2 0 DEC-1 protein, N-terminal region RWP-RK PF02042.15 RLN49803.1 - 4.4e-22 77.8 0.3 7.4e-22 77.1 0.3 1.4 1 0 0 1 1 1 1 RWP-RK domain Mito_carr PF00153.27 RLN49804.1 - 4.6e-59 196.4 0.5 1.6e-20 72.8 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein RED_N PF07808.13 RLN49805.1 - 1.1e-35 123.3 5.1 8.5e-33 113.9 0.0 3.7 2 2 2 4 4 4 2 RED-like protein N-terminal region DUF2225 PF09986.9 RLN49806.1 - 0.19 11.4 0.1 0.3 10.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Ribosomal_L19e PF01280.20 RLN49807.1 - 1.2e-60 203.7 9.8 1.2e-60 203.7 9.8 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e ATP_bind_1 PF03029.17 RLN49836.1 - 3.4e-46 158.0 0.4 7.8e-23 81.5 0.0 2.3 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein Beta-lactamase PF00144.24 RLN49836.1 - 5.2e-24 85.1 0.0 7.7e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase EF-hand_8 PF13833.6 RLN49836.1 - 0.0056 16.5 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair DUF1838 PF08894.11 RLN49836.1 - 0.017 14.9 0.1 0.032 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1838) Ank_2 PF12796.7 RLN49837.1 - 9e-17 61.5 0.6 9.1e-12 45.4 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN49837.1 - 2.5e-16 59.8 0.9 2.3e-07 31.2 0.0 5.0 3 1 2 5 5 5 3 Ankyrin repeats (many copies) FYVE PF01363.21 RLN49837.1 - 8.7e-16 57.8 7.5 1.7e-15 56.9 7.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger Ank_3 PF13606.6 RLN49837.1 - 5.2e-12 44.8 0.1 0.026 15.1 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 RLN49837.1 - 6.1e-11 42.3 1.0 0.00028 21.1 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN49837.1 - 6.3e-09 35.9 0.5 0.0003 21.1 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Siva PF05458.12 RLN49837.1 - 0.058 13.1 2.6 0.13 11.9 2.6 1.7 1 0 0 1 1 1 0 Cd27 binding protein (Siva) FYVE_2 PF02318.16 RLN49837.1 - 0.41 10.9 7.8 0.083 13.1 2.7 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger ASH PF15780.5 RLN49857.1 - 3.3e-24 84.9 8.4 6.2e-05 23.1 0.0 10.4 12 0 0 12 12 12 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 RLN49857.1 - 3.1e-13 49.7 8.7 0.0014 18.7 0.0 7.0 7 0 0 7 7 7 3 Flagellar-associated PapD-like TMEM131_like PF12371.8 RLN49857.1 - 7.2e-09 35.8 0.0 1.6 9.0 0.0 7.9 9 1 0 9 9 9 2 Transmembrane protein 131-like FTA4 PF13093.6 RLN49857.1 - 0.00073 19.5 0.4 0.0013 18.7 0.4 1.3 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Atg14 PF10186.9 RLN49857.1 - 0.063 12.3 8.3 0.11 11.6 8.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 7TMR-HDED PF07697.11 RLN49857.1 - 0.52 10.4 6.6 1.2 9.3 6.6 1.5 1 0 0 1 1 1 0 7TM-HD extracellular Exonuc_VII_L PF02601.15 RLN49857.1 - 0.81 9.2 4.7 1.8 8.1 4.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tyrosinase PF00264.20 RLN49879.1 - 8.9e-25 88.3 0.0 1.5e-24 87.5 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase TPR_17 PF13431.6 RLN49880.1 - 2.9e-15 55.5 6.3 0.0072 16.6 0.2 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 RLN49880.1 - 3e-09 36.4 7.1 0.28 11.5 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN49880.1 - 3.3e-09 36.2 1.9 1.6 8.7 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN49880.1 - 5.5e-09 35.5 8.2 0.8 10.0 0.6 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 RLN49880.1 - 3.1e-07 30.8 8.0 0.009 16.5 0.0 5.5 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN49880.1 - 2.4e-06 27.2 4.4 0.021 14.8 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN49880.1 - 1.1e-05 25.8 9.7 4.2 8.5 0.1 7.1 3 1 4 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN49880.1 - 2.4e-05 23.9 3.1 2.1 8.1 0.1 4.7 5 0 0 5 5 5 2 TPR repeat SAP PF02037.27 RLN49880.1 - 0.0093 15.7 3.7 3.9 7.3 0.2 3.5 2 2 0 2 2 2 2 SAP domain TPR_12 PF13424.6 RLN49880.1 - 0.012 15.9 14.8 1 9.7 0.0 5.4 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 RLN49880.1 - 0.034 14.3 5.2 1.2 9.4 0.3 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN49880.1 - 9.6 7.0 12.0 32 5.3 0.2 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat Mucin PF01456.17 RLN49881.1 - 0.87 9.6 27.7 0.035 14.1 14.8 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Rubredoxin_2 PF18073.1 RLN49882.1 - 0.67 9.7 3.9 18 5.2 0.0 3.4 3 0 0 3 3 3 0 Rubredoxin metal binding domain Palm_thioest PF02089.15 RLN49883.1 - 1.4e-46 159.3 0.0 1.8e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 RLN49883.1 - 0.0015 18.2 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN49883.1 - 0.0027 18.4 0.3 0.0051 17.4 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3530 PF12048.8 RLN49883.1 - 0.0034 16.8 0.0 0.0064 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) PGAP1 PF07819.13 RLN49883.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 RLN49883.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 RLN49883.1 - 0.026 14.1 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 RLN49883.1 - 0.046 13.0 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 CitF PF04223.12 RLN49883.1 - 0.088 11.7 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) Mucin PF01456.17 RLN49883.1 - 0.85 9.6 27.3 1.6 8.7 27.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF1263 PF06882.12 RLN49883.1 - 5.8 7.0 7.9 0.34 11.0 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1263) Complex1_LYR PF05347.15 RLN49884.1 - 6e-06 26.2 0.1 0.00053 20.0 0.1 2.1 1 1 0 1 1 1 1 Complex 1 protein (LYR family) DUF3767 PF12597.8 RLN49885.1 - 1.7e-12 47.0 0.1 2e-12 46.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) 5TM-5TMR_LYT PF07694.12 RLN49885.1 - 0.013 15.0 0.5 0.015 14.8 0.5 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT Ras PF00071.22 RLN49886.1 - 5e-24 84.7 0.1 1.9e-22 79.6 0.1 2.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RLN49886.1 - 3.9e-18 65.8 0.0 2.3e-17 63.3 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN49886.1 - 0.00035 20.1 0.1 0.055 12.9 0.0 3.1 2 1 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RLN49886.1 - 0.024 14.0 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF2199 PF09965.9 RLN49886.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) MMR_HSR1 PF01926.23 RLN49886.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ank_2 PF12796.7 RLN49888.1 - 1.4e-12 48.0 0.1 1.7e-06 28.5 0.1 3.4 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN49888.1 - 1.3e-06 28.9 5.8 0.024 15.2 0.0 4.9 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN49888.1 - 6.6e-05 23.0 4.8 0.61 10.8 0.0 5.5 6 1 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 RLN49888.1 - 0.00016 21.9 2.3 1.5 9.2 0.0 5.0 2 2 3 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN49888.1 - 0.0007 19.9 1.5 0.92 10.1 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 RLN49889.1 - 5.2e-13 49.4 0.0 3.5e-07 30.7 0.0 2.8 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN49889.1 - 1.3e-05 25.6 0.2 0.0034 17.9 0.0 3.7 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN49889.1 - 3.2e-05 24.0 0.1 2.4 9.0 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 RLN49889.1 - 0.0027 18.0 0.4 0.4 11.0 0.0 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) FlaF PF07309.11 RLN49889.1 - 0.13 12.2 3.7 0.48 10.5 0.1 2.6 2 0 0 2 2 2 0 Flagellar protein FlaF Ank_2 PF12796.7 RLN49890.1 - 3.3e-10 40.4 0.0 2.1e-05 25.0 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN49890.1 - 0.00044 20.5 0.0 52 4.9 0.0 4.5 4 0 0 4 4 4 0 Ankyrin repeat Ank_5 PF13857.6 RLN49890.1 - 0.07 13.5 0.3 0.82 10.1 0.2 2.8 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN49890.1 - 0.082 13.5 0.1 21 5.8 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 RLN49890.1 - 0.18 12.3 0.1 18 6.0 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat COG2 PF06148.11 RLN49891.1 - 0.005 16.9 1.5 0.0072 16.4 1.5 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Phage_HK97_TLTM PF06120.11 RLN49891.1 - 0.018 14.3 0.5 0.018 14.2 0.5 1.0 1 0 0 1 1 1 0 Tail length tape measure protein KH_1 PF00013.29 RLN49892.1 - 1.2e-63 210.9 12.2 2.8e-18 65.5 0.1 4.2 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 RLN49892.1 - 1.4e-13 50.5 7.6 8.8e-05 22.3 0.1 4.2 4 0 0 4 4 4 3 KH domain KH_2 PF07650.17 RLN49892.1 - 2.2e-11 43.4 10.0 0.0027 17.5 0.0 4.3 4 0 0 4 4 4 4 KH domain KH_5 PF13184.6 RLN49892.1 - 5.8e-05 23.1 3.4 3.6 7.7 0.0 4.3 4 0 0 4 4 4 3 NusA-like KH domain Myb_DNA-bind_7 PF15963.5 RLN49893.1 - 1.7e-24 85.5 0.1 3.5e-24 84.5 0.1 1.4 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 RLN49893.1 - 0.0013 18.8 0.0 0.0023 18.1 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pkinase_Tyr PF07714.17 RLN49894.1 - 1e-15 57.8 0.0 1.4e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN49894.1 - 7.8e-14 51.7 0.0 1e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 RLN49894.1 - 0.019 14.9 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Elicitin PF00964.17 RLN49895.1 - 5.3e-21 74.5 3.2 5.3e-21 74.5 3.2 1.9 2 0 0 2 2 2 1 Elicitin PPR_2 PF13041.6 RLN49906.1 - 3.9e-05 23.8 0.0 0.064 13.5 0.0 3.4 3 0 0 3 3 3 2 PPR repeat family 2H-phosphodiest PF08975.10 RLN49906.1 - 0.11 12.4 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) Pex19 PF04614.12 RLN49906.1 - 4.1 7.1 6.0 9.5 5.9 0.0 3.2 3 1 0 3 3 3 0 Pex19 protein family Vasohibin PF14822.6 RLN49907.1 - 1.8e-49 168.2 0.1 2.6e-49 167.6 0.1 1.1 1 0 0 1 1 1 1 Vasohibin MORN PF02493.20 RLN49908.1 - 1e-35 119.5 35.4 3.2e-05 23.6 0.2 9.3 9 0 0 9 9 9 8 MORN repeat PI3_PI4_kinase PF00454.27 RLN49911.1 - 9.4e-33 114.1 0.0 1.1e-24 87.6 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase FYVE PF01363.21 RLN49911.1 - 1.2e-06 28.6 15.9 1.2e-06 28.6 15.9 1.8 2 0 0 2 2 2 1 FYVE zinc finger DEP PF00610.21 RLN49911.1 - 6.5e-06 26.1 0.0 1.8e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 RLN49911.1 - 0.0059 17.1 0.0 0.015 15.8 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF4135 PF13575.6 RLN49911.1 - 0.0097 15.3 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) IBR PF01485.21 RLN49911.1 - 0.036 14.3 6.0 0.13 12.6 6.0 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain PH_11 PF15413.6 RLN49911.1 - 0.11 12.9 0.9 0.86 10.1 0.1 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain Zip PF02535.22 RLN49915.1 - 2.1e-24 86.4 8.0 8.6e-24 84.4 8.0 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Cu-oxidase_2 PF07731.14 RLN49915.1 - 5.6e-12 45.6 4.3 1.8e-11 44.0 4.3 1.8 1 1 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN49915.1 - 6.1e-12 45.6 2.5 2.7e-07 30.6 0.1 3.5 3 0 0 3 3 3 2 Multicopper oxidase LEP503 PF15221.6 RLN49915.1 - 0.034 14.5 0.1 0.076 13.3 0.1 1.6 1 0 0 1 1 1 0 Lens epithelial cell protein LEP503 Zip PF02535.22 RLN49916.1 - 5.4e-30 104.8 8.1 8.4e-30 104.1 8.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Cu-oxidase_2 PF07731.14 RLN49916.1 - 2.1e-11 43.7 4.2 1.3e-09 37.9 4.7 2.9 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN49916.1 - 1.7e-09 37.7 3.2 7.3e-06 26.0 0.1 3.6 4 0 0 4 4 4 2 Multicopper oxidase LEP503 PF15221.6 RLN49916.1 - 0.011 16.1 0.2 0.025 14.9 0.2 1.6 1 0 0 1 1 1 0 Lens epithelial cell protein LEP503 Cu-oxidase PF00394.22 RLN49916.1 - 0.021 14.9 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Multicopper oxidase DUF4601 PF15373.6 RLN49916.1 - 0.22 10.4 0.0 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) MotA_ExbB PF01618.16 RLN49916.1 - 1.5 8.6 5.9 0.36 10.6 0.6 2.7 3 0 0 3 3 3 0 MotA/TolQ/ExbB proton channel family PP2C PF00481.21 RLN49917.1 - 3.3e-47 161.3 0.0 8.1e-47 160.0 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C DUF1682 PF07946.14 RLN49917.1 - 7 5.8 12.1 12 5.0 12.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) GST_N_3 PF13417.6 RLN49918.1 - 1.1e-15 57.8 0.0 1.8e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RLN49918.1 - 1.8e-15 57.0 0.0 3.8e-15 56.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN49918.1 - 4.3e-11 43.0 0.0 7.3e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN49918.1 - 5.1e-05 23.2 0.4 0.032 14.3 0.0 2.6 2 1 1 3 3 3 2 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RLN49918.1 - 0.00061 19.9 0.0 0.00098 19.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 RLN49918.1 - 0.0011 19.1 0.0 0.0042 17.3 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin GST_C PF00043.25 RLN49918.1 - 0.0029 17.8 0.0 0.0053 16.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Histone PF00125.24 RLN49921.1 - 2.3e-39 134.8 1.7 2.7e-39 134.5 1.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 RLN49921.1 - 0.00033 21.0 0.0 0.00045 20.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 RLN49921.1 - 0.002 18.2 0.1 0.0025 17.9 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 RLN49921.1 - 0.0025 18.1 0.1 0.0035 17.6 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 RLN49921.1 - 0.025 14.6 0.0 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF1542 PF07564.11 RLN49923.1 - 0.21 11.7 3.5 0.44 10.7 3.5 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Acetyltransf_1 PF00583.25 RLN49953.1 - 2.9e-11 43.6 0.0 3.7e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RLN49953.1 - 2.5e-09 37.1 0.1 3.7e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN49953.1 - 8e-09 35.8 0.2 1.3e-08 35.2 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN49953.1 - 1.5e-07 31.3 0.0 2.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 RLN49953.1 - 0.00049 20.2 0.1 0.0011 19.0 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Complex1_LYR PF05347.15 RLN49954.1 - 1.3e-10 41.2 0.6 2.3e-10 40.3 0.6 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 RLN49954.1 - 0.052 14.3 0.2 0.096 13.4 0.2 1.5 1 0 0 1 1 1 0 Complex1_LYR-like SET PF00856.28 RLN49955.1 - 4.7e-10 40.1 0.0 2.3e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 SET domain AA_permease_2 PF13520.6 RLN49956.1 - 7.5e-13 48.1 9.5 8.6e-13 47.9 9.5 1.0 1 0 0 1 1 1 1 Amino acid permease DnaJ_C PF01556.18 RLN49956.1 - 0.13 12.3 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 DnaJ C terminal domain AA_permease_2 PF13520.6 RLN49957.1 - 2.9e-45 154.9 40.8 4.1e-45 154.4 40.8 1.2 1 0 0 1 1 1 1 Amino acid permease SHS2_Rpb7-N PF03876.17 RLN49957.1 - 3.9e-12 46.4 0.0 1.1e-11 44.9 0.0 1.9 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 RLN49957.1 - 1.2e-09 38.4 0.1 1.2e-09 38.4 0.1 2.0 2 0 0 2 2 2 1 S1 RNA binding domain Got1 PF04178.12 RLN49962.1 - 1.1e-16 61.2 13.4 1.4e-16 60.9 13.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.13 RLN49962.1 - 0.044 14.1 16.1 0.46 10.9 6.0 2.2 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) DUF2157 PF09925.9 RLN49962.1 - 0.32 10.8 8.5 0.43 10.4 8.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Anoctamin PF04547.12 RLN49962.1 - 6 5.6 5.5 1.9 7.2 2.8 1.5 1 1 0 1 1 1 0 Calcium-activated chloride channel FlaC_arch PF05377.11 RLN49963.1 - 0.33 11.4 1.9 0.65 10.4 0.4 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) GTP_cyclohydro2 PF00925.20 RLN49964.1 - 2.5e-56 189.8 0.0 3.9e-56 189.1 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II TPR_12 PF13424.6 RLN49965.1 - 4.4e-26 91.0 6.4 9.6e-11 41.8 0.1 4.7 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 RLN49965.1 - 3e-17 61.9 1.5 5.2e-06 26.2 0.0 5.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN49965.1 - 4.3e-12 45.2 6.6 0.12 12.5 0.0 5.6 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 RLN49965.1 - 1.2e-11 44.4 7.6 0.049 14.5 0.0 5.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN49965.1 - 7.3e-07 28.8 0.6 3.6 7.8 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN49965.1 - 1.6e-06 28.5 8.3 0.16 12.5 0.8 5.0 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 RLN49965.1 - 3.9e-06 27.4 4.2 2.2 9.0 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.17 RLN49965.1 - 9.3e-06 26.1 0.7 0.00017 22.0 0.0 2.6 2 1 0 2 2 2 1 Bacterial transcriptional activator domain TPR_8 PF13181.6 RLN49965.1 - 1e-05 25.3 10.9 0.067 13.4 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN49965.1 - 0.00075 19.2 6.8 6.6 6.7 0.6 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN49965.1 - 0.0013 18.4 2.0 1.1 9.0 1.1 4.1 6 0 0 6 6 5 1 TPR repeat TPR_17 PF13431.6 RLN49965.1 - 0.012 15.9 0.1 13 6.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN49965.1 - 0.024 15.3 6.1 87 4.1 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 RLN49965.1 - 0.024 14.7 2.5 2.5 8.2 0.1 3.2 1 1 2 3 3 3 0 Domain of Unknown Function (DUF3856) ANAPC5 PF12862.7 RLN49965.1 - 0.026 14.6 1.6 2.3 8.3 0.2 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 ANAPC3 PF12895.7 RLN49965.1 - 0.03 14.5 3.4 5.3 7.3 0.0 3.9 1 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 FSH1 PF03959.13 RLN49965.1 - 0.14 11.8 0.0 0.76 9.4 0.0 2.0 2 1 0 2 2 2 0 Serine hydrolase (FSH1) SPOB_a PF14689.6 RLN49965.1 - 0.19 11.5 0.5 26 4.6 0.0 2.9 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain HisG PF01634.18 RLN49966.1 - 4.7e-53 179.4 0.1 7e-53 178.9 0.1 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 RLN49966.1 - 1.1e-22 80.0 0.0 1.9e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 RLN49966.1 - 2.1e-05 24.6 0.1 3.3e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 NMT1/THI5 like Sec7_N PF12783.7 RLN49966.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal YL1 PF05764.13 RLN49967.1 - 8.1e-32 111.3 10.7 8.1e-32 111.3 10.7 2.4 2 0 0 2 2 2 1 YL1 nuclear protein DUF4061 PF13270.6 RLN49967.1 - 8.5 6.8 10.1 0.72 10.2 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) PQ-loop PF04193.14 RLN49968.1 - 3e-26 91.0 3.9 2.1e-12 46.6 0.6 2.5 2 0 0 2 2 2 2 PQ loop repeat PPR_2 PF13041.6 RLN49972.1 - 2.9e-11 43.4 0.0 0.16 12.2 0.0 6.2 5 2 2 7 7 7 3 PPR repeat family PPR_long PF17177.4 RLN49972.1 - 1.4e-08 34.3 3.8 0.00015 21.2 0.0 3.4 1 1 2 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 RLN49972.1 - 1e-07 31.7 0.0 0.065 13.5 0.0 6.2 6 0 0 6 6 6 1 PPR repeat PPR_3 PF13812.6 RLN49972.1 - 2.8e-07 30.5 0.2 5.3 7.2 0.0 5.8 3 1 5 8 8 8 3 Pentatricopeptide repeat domain adh_short PF00106.25 RLN49973.1 - 7.9e-15 54.8 0.0 2.8e-14 53.0 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN49973.1 - 2.3e-10 40.4 0.0 2.7e-09 36.9 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Dynein_C PF18199.1 RLN49974.1 - 1.2e-111 372.8 0.0 1.4e-111 372.7 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain PPR_2 PF13041.6 RLN49975.1 - 3e-18 65.7 0.0 0.0083 16.3 0.0 11.2 11 3 2 13 13 13 2 PPR repeat family PPR PF01535.20 RLN49975.1 - 5.5e-17 60.7 0.0 0.78 10.1 0.0 11.3 11 0 0 11 11 11 3 PPR repeat PPR_3 PF13812.6 RLN49975.1 - 2.9e-15 56.1 0.0 0.046 13.8 0.0 9.8 8 3 1 11 11 11 3 Pentatricopeptide repeat domain PPR_long PF17177.4 RLN49975.1 - 7.9e-14 51.5 14.0 0.00078 18.9 0.1 7.0 2 2 5 8 8 8 5 Pentacotripeptide-repeat region of PRORP MNE1 PF13762.6 RLN49975.1 - 0.0099 15.9 1.8 5.6 6.9 0.1 4.0 4 1 0 4 4 4 1 Mitochondrial splicing apparatus component Mic1 PF07035.12 RLN49975.1 - 0.012 15.4 0.2 3.6 7.3 0.0 3.8 3 0 0 3 3 3 0 Colon cancer-associated protein Mic1-like CPDase PF07823.11 RLN49975.1 - 0.02 14.6 0.0 1.3 8.7 0.0 2.8 3 0 0 3 3 3 0 Cyclic phosphodiesterase-like protein Dimerisation PF08100.11 RLN49975.1 - 0.14 12.2 2.7 17 5.5 0.2 4.0 4 0 0 4 4 4 0 Dimerisation domain Chlamy_scaf PF09675.10 RLN49975.1 - 0.21 11.9 0.7 7.7 6.9 0.0 3.3 4 0 0 4 4 3 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) TPR_19 PF14559.6 RLN49975.1 - 0.85 10.2 23.5 8.4 7.0 1.3 6.5 5 1 0 5 5 5 0 Tetratricopeptide repeat eIF3_subunit PF08597.10 RLN49975.1 - 1.4 8.8 7.6 0.22 11.4 1.9 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit TPR_12 PF13424.6 RLN49975.1 - 2.3 8.5 17.4 3.3 8.1 0.4 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Myb_DNA-bind_4 PF13837.6 RLN49976.1 - 0.03 14.7 0.6 0.11 13.0 0.0 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain FANCL_C PF11793.8 RLN49976.1 - 0.043 14.0 2.4 1.2 9.4 1.6 2.6 2 0 0 2 2 2 0 FANCL C-terminal domain HK97-gp10_like PF04883.12 RLN49976.1 - 0.091 13.8 1.3 5.6 8.0 1.0 2.7 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component zf-RING-like PF08746.11 RLN49976.1 - 0.15 12.4 2.0 0.23 11.8 0.4 2.1 2 0 0 2 2 2 0 RING-like domain SBP_bac_11 PF13531.6 RLN49977.1 - 2.3e-21 76.6 0.3 2.9e-21 76.3 0.3 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 RLN49977.1 - 2.1e-07 31.2 0.3 2.8e-07 30.8 0.3 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 RLN49977.1 - 1.3e-05 24.8 0.1 0.00016 21.2 0.0 2.1 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 RLN49977.1 - 0.0019 18.1 0.2 0.003 17.4 0.2 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein EF-hand_1 PF00036.32 RLN49978.1 - 2.8e-14 51.5 5.2 6.9e-06 25.3 0.2 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 RLN49978.1 - 4.1e-11 41.9 2.6 0.00032 20.4 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 RLN49978.1 - 4.8e-10 39.7 3.9 3.7e-09 36.9 2.6 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN49978.1 - 1.3e-08 33.9 10.6 5e-05 22.6 0.9 3.1 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 RLN49978.1 - 0.00015 21.5 5.2 0.21 11.5 0.2 3.1 2 1 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RLN49978.1 - 0.023 15.0 0.3 0.023 15.0 0.3 1.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 RLN49978.1 - 0.025 14.9 0.0 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain DAGK_cat PF00781.24 RLN49979.1 - 9.7e-26 89.9 0.1 1.5e-25 89.3 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SIP1 PF04938.12 RLN50003.1 - 6.5e-54 182.9 0.0 7.9e-54 182.7 0.0 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Abhydrolase_6 PF12697.7 RLN50004.1 - 0.067 13.8 0.0 0.081 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DEAD PF00270.29 RLN50005.1 - 3e-48 163.9 0.8 5.9e-48 162.9 0.8 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN50005.1 - 3.9e-20 72.2 0.0 2.9e-19 69.5 0.0 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 RLN50005.1 - 2.7e-16 59.5 0.6 2.7e-16 59.5 0.6 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4217) ResIII PF04851.15 RLN50005.1 - 1.7e-09 37.9 0.0 4.6e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RLN50005.1 - 0.029 14.6 0.7 0.26 11.5 0.7 2.6 1 1 0 1 1 1 0 AAA domain Hint PF01079.20 RLN50006.1 - 0.15 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Hint module MULE PF10551.9 RLN50009.1 - 4.1e-18 65.6 0.2 8e-18 64.6 0.2 1.5 1 0 0 1 1 1 1 MULE transposase domain SET PF00856.28 RLN50010.1 - 2.5e-08 34.5 0.1 3.2e-07 30.9 0.1 2.3 1 1 0 1 1 1 1 SET domain DUF4717 PF15838.5 RLN50010.1 - 0.024 14.6 0.1 0.059 13.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4717) AWS PF17907.1 RLN50010.1 - 0.027 14.5 5.3 0.068 13.2 5.3 1.7 1 0 0 1 1 1 0 AWS domain Elicitin PF00964.17 RLN50013.1 - 2.1e-17 63.0 7.1 2.1e-17 63.0 7.1 2.1 2 0 0 2 2 2 1 Elicitin Ank_2 PF12796.7 RLN50014.1 - 3.2e-96 316.0 25.6 2.6e-16 60.0 0.4 10.2 4 3 7 12 12 12 10 Ankyrin repeats (3 copies) Mo25 PF08569.11 RLN50014.1 - 1.8e-91 307.0 6.5 1.8e-91 307.0 4.3 2.0 2 1 0 2 2 2 1 Mo25-like Ank_4 PF13637.6 RLN50014.1 - 1.9e-77 254.7 23.0 2.1e-13 50.5 0.0 12.5 9 2 5 14 14 14 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN50014.1 - 4.1e-74 243.7 42.2 9.9e-09 35.3 0.2 15.7 4 3 12 16 16 16 16 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN50014.1 - 3e-67 214.6 22.1 4.8e-05 23.4 0.0 17.4 17 0 0 17 17 17 13 Ankyrin repeat Ank PF00023.30 RLN50014.1 - 2e-65 214.6 55.6 5e-07 29.9 0.3 17.0 17 0 0 17 17 17 14 Ankyrin repeat VWA_3_C PF18571.1 RLN50014.1 - 0.2 11.5 2.9 8 6.4 0.0 4.4 4 1 0 4 4 4 0 von Willebrand factor type A C-terminal domain DUF1843 PF08898.10 RLN50014.1 - 0.46 11.0 3.3 11 6.7 0.1 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DUF2345 PF10106.9 RLN50015.1 - 0.034 14.0 5.3 0.14 12.0 5.1 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) Pkinase PF00069.25 RLN50053.1 - 1.6e-28 99.8 0.0 2e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN50053.1 - 3.7e-15 55.9 0.0 4.7e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN50054.1 - 3e-59 200.6 0.0 1.7e-38 132.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN50054.1 - 2.7e-30 105.5 0.0 3.4e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN50054.1 - 1.9e-05 24.7 0.1 0.00013 22.0 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN50054.1 - 0.061 12.1 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 RLN50054.1 - 0.09 12.1 0.0 0.5 9.6 0.0 2.0 1 1 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 RLN50054.1 - 0.19 10.7 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Peptidase_S8 PF00082.22 RLN50056.1 - 4.7e-29 101.6 1.5 5e-29 101.5 1.5 1.0 1 0 0 1 1 1 1 Subtilase family DUF4969 PF16339.5 RLN50057.1 - 0.0065 16.8 0.4 0.0065 16.8 0.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4969) Reprolysin_5 PF13688.6 RLN50057.1 - 0.0067 16.6 0.0 0.0067 16.6 0.0 3.1 2 1 1 3 3 3 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 RLN50057.1 - 0.45 11.0 0.1 0.45 11.0 0.1 2.3 3 0 0 3 3 3 0 Metallo-peptidase family M12B Reprolysin-like DUF966 PF06136.13 RLN50057.1 - 4.8 6.8 8.7 6.4 6.4 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) RAP1 PF07218.11 RLN50057.1 - 7.9 4.6 9.7 11 4.2 9.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SWI-SNF_Ssr4 PF08549.10 RLN50057.1 - 9 4.8 13.3 12 4.3 13.3 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) fn3 PF00041.21 RLN50086.1 - 4.9e-37 126.1 15.4 7.9e-05 22.9 0.3 12.1 11 1 0 11 11 11 8 Fibronectin type III domain DUF2369 PF10179.9 RLN50086.1 - 0.016 15.6 0.2 17 5.8 0.0 4.3 5 0 0 5 5 5 0 Uncharacterised conserved protein (DUF2369) Pur_ac_phosph_N PF16656.5 RLN50086.1 - 2.7 8.6 17.2 54 4.5 0.0 7.9 8 1 0 8 8 8 0 Purple acid Phosphatase, N-terminal domain zf-C3HC4_2 PF13923.6 RLN50089.1 - 1.1e-09 37.9 8.5 2.7e-09 36.7 8.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN50089.1 - 1.3e-09 37.9 6.7 7.2e-09 35.5 6.9 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RLN50089.1 - 1.2e-08 34.7 6.8 2.1e-08 33.9 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RLN50089.1 - 4.4e-08 33.2 7.3 8.9e-08 32.2 7.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 RLN50089.1 - 1.1e-07 32.1 9.0 2.5e-07 30.9 9.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RLN50089.1 - 2e-07 30.8 5.1 3.1e-07 30.1 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN50089.1 - 9e-07 28.8 6.1 1.8e-06 27.8 6.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain FYVE PF01363.21 RLN50089.1 - 0.0018 18.4 2.1 0.0018 18.4 2.1 1.8 2 0 0 2 2 1 1 FYVE zinc finger zf-Nse PF11789.8 RLN50089.1 - 0.0024 17.6 2.8 0.0048 16.7 2.8 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 RLN50089.1 - 0.0064 16.3 8.5 0.083 12.8 7.6 2.4 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 ORC2 PF04084.14 RLN50089.1 - 0.03 13.2 0.1 0.057 12.3 0.1 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 2 zf-RING_6 PF14835.6 RLN50089.1 - 0.056 13.3 1.9 0.11 12.4 1.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.11 RLN50089.1 - 0.062 13.3 0.8 0.11 12.5 0.8 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DUF2712 PF10916.8 RLN50089.1 - 0.14 12.9 0.1 0.33 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2712) zf-ANAPC11 PF12861.7 RLN50089.1 - 0.18 11.8 5.5 0.43 10.7 4.8 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 RLN50089.1 - 0.69 10.3 10.7 2.7 8.4 10.4 2.1 1 1 1 2 2 2 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 RLN50089.1 - 0.79 9.5 8.8 0.52 10.1 5.7 2.2 2 0 0 2 2 2 0 RING-like zinc finger Complex1_LYR PF05347.15 RLN50090.1 - 9e-13 48.1 0.7 1.3e-12 47.6 0.7 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 RLN50090.1 - 0.00031 21.4 0.0 0.00039 21.1 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 RLN50090.1 - 0.0019 18.8 0.1 0.0024 18.4 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like SKA2 PF16740.5 RLN50090.1 - 0.025 14.4 0.2 0.044 13.6 0.2 1.4 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 LemA PF04011.12 RLN50090.1 - 0.084 12.7 0.1 0.48 10.3 0.0 1.8 1 1 1 2 2 2 0 LemA family DUF3510 PF12022.8 RLN50090.1 - 0.17 12.3 1.2 0.64 10.4 1.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) WLM PF08325.10 RLN50092.1 - 6.5e-18 65.5 2.9 1.8e-17 64.1 0.1 2.4 1 1 2 3 3 3 1 WLM domain SVIP PF15811.5 RLN50092.1 - 0.0023 18.4 3.3 0.0023 18.4 3.3 2.7 3 1 0 3 3 3 1 Small VCP/p97-interacting protein RXT2_N PF08595.11 RLN50092.1 - 0.38 10.8 3.5 0.41 10.7 0.2 2.3 3 0 0 3 3 3 0 RXT2-like, N-terminal VPS11_C PF12451.8 RLN50093.1 - 5.5e-13 48.9 0.2 5.5e-13 48.9 0.2 1.8 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 RLN50093.1 - 3.1e-05 23.9 9.4 3.1e-05 23.9 9.4 2.0 2 0 0 2 2 2 1 Zinc-finger Clathrin PF00637.20 RLN50093.1 - 0.00012 21.9 6.4 0.00042 20.2 0.1 3.4 3 0 0 3 3 3 1 Region in Clathrin and VPS Vps39_2 PF10367.9 RLN50093.1 - 0.00024 21.5 4.0 0.00049 20.5 2.6 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 DUF4456 PF14644.6 RLN50093.1 - 0.0025 17.5 0.1 0.0025 17.5 0.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4456) zf-C3HC4_2 PF13923.6 RLN50093.1 - 0.081 12.8 9.8 0.15 11.9 9.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN50093.1 - 0.085 13.2 6.9 0.21 11.9 6.9 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain Chromosome_seg PF13889.6 RLN50093.1 - 0.13 12.4 0.7 0.45 10.7 0.7 1.9 1 0 0 1 1 1 0 Chromosome segregation during meiosis zf-RING_2 PF13639.6 RLN50093.1 - 0.14 12.5 9.7 0.26 11.6 9.7 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 RLN50093.1 - 0.2 11.7 8.3 0.39 10.8 8.3 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 RLN50093.1 - 1.1 9.3 8.6 2.1 8.4 8.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Na_Ca_ex PF01699.24 RLN50094.1 - 5.4e-33 114.1 29.0 1.3e-17 64.2 12.0 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein FMN_red PF03358.15 RLN50095.1 - 5.7e-13 48.9 0.0 7.6e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 RLN50095.1 - 3.2e-06 27.0 0.0 3.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 RLN50095.1 - 0.0001 22.5 0.1 0.00019 21.6 0.1 1.4 1 1 0 1 1 1 1 Flavodoxin DAGK_acc PF00609.19 RLN50096.1 - 6.8e-53 179.3 0.0 1.2e-52 178.5 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 RLN50096.1 - 5.8e-25 87.3 0.0 1.2e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 RLN50096.1 - 2.6e-17 62.5 14.2 3.3e-10 39.7 5.1 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 RLN50096.1 - 0.00087 19.1 11.4 0.006 16.4 0.6 2.5 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 RLN50096.1 - 0.0038 16.7 7.0 0.24 11.0 1.0 2.9 2 0 0 2 2 2 2 PHD-finger C1_2 PF03107.16 RLN50096.1 - 0.009 16.3 11.2 0.015 15.6 1.4 2.5 2 0 0 2 2 2 1 C1 domain Zf_RING PF16744.5 RLN50096.1 - 0.08 13.1 6.7 1.1 9.5 0.5 2.4 2 0 0 2 2 2 0 KIAA1045 RING finger PHD_4 PF16866.5 RLN50096.1 - 0.12 12.5 5.2 3.3 7.9 0.5 2.7 2 0 0 2 2 2 0 PHD-finger zf-RING-like PF08746.11 RLN50096.1 - 0.17 12.2 14.7 0.15 12.3 4.9 2.5 2 0 0 2 2 2 0 RING-like domain Zn_ribbon_17 PF17120.5 RLN50096.1 - 1 9.1 11.0 0.51 10.0 1.0 2.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PCRF PF03462.18 RLN50097.1 - 4.6e-50 170.2 0.2 7.2e-50 169.5 0.2 1.3 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 RLN50097.1 - 1.8e-37 127.8 0.0 3.5e-37 126.9 0.0 1.5 1 0 0 1 1 1 1 RF-1 domain LRR_6 PF13516.6 RLN50098.1 - 4.7e-23 79.2 17.1 0.0051 16.8 0.0 9.3 9 0 0 9 9 9 5 Leucine Rich repeat LRR_1 PF00560.33 RLN50098.1 - 0.00074 19.7 7.4 4.3 8.3 0.1 7.0 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_4 PF12799.7 RLN50098.1 - 0.0026 18.1 15.8 3.9 8.0 0.5 6.2 4 2 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN50098.1 - 0.0029 17.3 18.3 1.9 8.3 0.0 7.3 4 1 4 8 8 8 3 Leucine rich repeat MORN PF02493.20 RLN50099.1 - 9.5e-14 50.4 31.1 5.1e-07 29.2 1.8 4.8 6 0 0 6 6 6 3 MORN repeat DSPc PF00782.20 RLN50100.1 - 4.5e-30 104.2 0.2 7.9e-30 103.4 0.2 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 RLN50100.1 - 2.4e-06 28.0 0.0 1.1e-05 25.9 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 RLN50100.1 - 0.0001 22.0 0.1 0.00016 21.3 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 RLN50100.1 - 0.0055 16.8 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Mito_carr PF00153.27 RLN50101.1 - 5.2e-44 148.1 0.5 5.7e-19 67.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 RLN50101.1 - 0.00084 18.6 0.0 0.03 13.5 0.0 2.4 1 1 1 2 2 2 2 Gammaproteobacterial serine protease COPI_assoc PF08507.10 RLN50102.1 - 7.8e-10 38.9 4.3 1.2e-09 38.3 4.3 1.3 1 0 0 1 1 1 1 COPI associated protein ETC_C1_NDUFA4 PF04800.12 RLN50103.1 - 1.2e-27 95.9 0.1 2.5e-27 95.0 0.1 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region Trehalose_PPase PF02358.16 RLN50104.1 - 3.7e-53 180.1 0.0 4.6e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 RLN50104.1 - 0.00029 20.6 0.0 0.051 13.3 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase DarA_N PF18788.1 RLN50104.1 - 0.17 12.0 0.0 0.44 10.6 0.0 1.7 1 0 0 1 1 1 0 Defence against restriction A N-terminal Cofilin_ADF PF00241.20 RLN50111.1 - 2.9e-23 82.0 0.0 3.6e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein TauD PF02668.16 RLN50112.1 - 4.1e-38 131.7 2.4 5.2e-38 131.4 2.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 RLN50112.1 - 0.0022 17.2 0.0 0.0056 15.8 0.0 1.6 2 0 0 2 2 2 1 CsiD DUF971 PF06155.12 RLN50112.1 - 0.0041 17.7 0.0 0.0096 16.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) zf-HC5HC2H_2 PF13832.6 RLN50113.1 - 1.2e-09 38.3 5.6 1.2e-09 38.3 5.6 4.5 4 1 1 5 5 5 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RLN50113.1 - 4.2e-09 36.5 5.8 4.2e-09 36.5 5.8 4.2 3 1 1 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.6 RLN50113.1 - 0.00031 20.2 0.4 0.00031 20.2 0.4 3.6 3 0 0 3 3 3 1 PHD-finger Amino_oxidase PF01593.24 RLN50114.1 - 7.9e-56 190.2 0.0 1.1e-55 189.7 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RLN50114.1 - 5e-10 39.5 0.1 1.7e-09 37.8 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Fringe PF02434.16 RLN50114.1 - 2e-09 37.3 0.2 3.6e-09 36.4 0.2 1.3 1 0 0 1 1 1 1 Fringe-like NAD_binding_9 PF13454.6 RLN50114.1 - 3e-08 33.8 0.1 0.00016 21.7 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Galactosyl_T PF01762.21 RLN50114.1 - 7.4e-06 25.9 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Pyr_redox_2 PF07992.14 RLN50114.1 - 0.00014 21.2 0.0 0.028 13.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RLN50114.1 - 0.0012 18.5 1.3 0.0064 16.1 1.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 RLN50114.1 - 0.017 14.2 0.2 3.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 RLN50114.1 - 0.086 11.5 0.2 2.3 6.8 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 RLN50114.1 - 0.1 11.9 0.3 0.32 10.3 0.2 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 RLN50114.1 - 0.27 10.4 0.3 3.2 6.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 RLN50115.1 - 1e-72 245.9 0.0 1.2e-72 245.7 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RLN50115.1 - 4e-11 43.0 0.1 7.8e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 RLN50115.1 - 3.5e-08 33.6 0.3 0.00032 20.7 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 RLN50115.1 - 1e-06 28.6 2.0 1.5e-05 24.7 2.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RLN50115.1 - 0.0016 17.7 0.4 0.023 13.9 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RLN50115.1 - 0.0033 17.9 0.1 0.014 15.9 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 RLN50115.1 - 0.011 14.6 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 MCRA family HI0933_like PF03486.14 RLN50115.1 - 0.013 14.3 0.3 0.18 10.5 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 RLN50115.1 - 0.024 13.9 0.1 4.6 6.4 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RLN50115.1 - 0.029 13.4 3.0 0.34 9.9 0.3 2.9 3 1 0 3 3 3 0 Lycopene cyclase protein FAD_oxidored PF12831.7 RLN50115.1 - 0.03 13.7 0.0 0.054 12.8 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF3040 PF11239.8 RLN50115.1 - 0.038 14.3 1.1 0.092 13.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) FAD_binding_2 PF00890.24 RLN50115.1 - 0.062 12.4 1.2 0.12 11.5 1.2 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 RLN50115.1 - 0.1 11.8 0.2 0.19 10.9 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 RLN50115.1 - 0.15 11.1 0.8 0.3 10.1 0.8 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 RLN50115.1 - 0.15 11.3 0.1 0.28 10.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family TetR_C_16 PF17920.1 RLN50115.1 - 0.26 11.5 1.4 11 6.3 0.0 2.7 3 0 0 3 3 2 0 Tetracyclin repressor-like, C-terminal domain ANAPC4_WD40 PF12894.7 RLN50116.1 - 1.5e-13 50.9 0.1 8.2e-13 48.5 0.0 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain ANAPC4 PF12896.7 RLN50116.1 - 8.5e-07 28.7 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4 PF12896.7 RLN50117.1 - 1.1e-09 38.2 0.4 1.4e-09 37.7 0.4 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Myc_N PF01056.18 RLN50117.1 - 0.007 16.3 1.7 0.011 15.6 0.2 2.0 2 0 0 2 2 2 1 Myc amino-terminal region Hex_IIIa PF02455.16 RLN50117.1 - 0.16 10.7 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) CCDC53 PF10152.9 RLN50117.1 - 2.3 8.6 6.4 5.7 7.3 6.4 1.6 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex PBP1_TM PF14812.6 RLN50117.1 - 9.4 6.7 12.5 1.1 9.7 2.1 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ion_trans PF00520.31 RLN50118.1 - 3e-45 154.4 37.5 3.5e-23 82.1 12.5 2.2 2 0 0 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 RLN50118.1 - 2.9e-19 68.8 19.4 1e-11 44.6 6.3 2.8 2 0 0 2 2 2 2 Ion channel cNMP_binding PF00027.29 RLN50118.1 - 1.3e-13 50.8 0.1 9.5e-06 25.6 0.0 3.4 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Trehalose_PPase PF02358.16 RLN50119.1 - 1.8e-51 174.6 0.0 2.2e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 RLN50119.1 - 0.0011 18.7 0.0 0.24 11.1 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 RLN50119.1 - 0.0088 15.6 0.0 3.9 6.9 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Ribosomal_L32p PF01783.23 RLN50120.1 - 6.6e-09 35.9 2.8 1.2e-08 35.1 2.8 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family GCV_T PF01571.21 RLN50121.1 - 2.1e-13 50.2 0.1 3.4e-13 49.6 0.1 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain TPR_1 PF00515.28 RLN50122.1 - 3.4e-09 36.1 0.2 8.4e-05 22.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 RLN50122.1 - 3.4e-06 26.7 0.2 0.014 15.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN50122.1 - 1.5e-05 24.7 0.2 0.0017 18.2 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN50122.1 - 0.00046 20.4 2.1 0.01 16.1 0.0 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN50122.1 - 0.004 17.2 0.0 0.017 15.3 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN50122.1 - 0.0056 16.3 0.1 0.47 10.2 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 RLN50122.1 - 0.019 15.6 7.8 0.021 15.5 1.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN50122.1 - 0.025 15.4 3.6 0.15 13.0 0.1 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat FlxA PF14282.6 RLN50122.1 - 0.034 14.2 4.9 0.083 12.9 4.9 1.6 1 0 0 1 1 1 0 FlxA-like protein Agenet PF05641.12 RLN50122.1 - 0.038 14.5 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 Agenet domain TPR_10 PF13374.6 RLN50122.1 - 0.053 13.4 0.0 0.28 11.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Mhr1 PF12829.7 RLN50122.1 - 0.073 13.2 0.2 0.28 11.3 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulation of mitochondrial recombination TPR_6 PF13174.6 RLN50122.1 - 1.3 9.8 6.1 5 8.0 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribonucleas_3_3 PF14622.6 RLN50123.1 - 1.5e-43 148.0 0.2 9.7e-21 74.3 0.0 3.3 3 0 0 3 3 3 3 Ribonuclease-III-like Ribonuclease_3 PF00636.26 RLN50123.1 - 3.6e-36 124.0 0.4 5.4e-18 65.5 0.1 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Torus PF16131.5 RLN50124.1 - 5.5e-09 36.7 0.0 1.1e-08 35.7 0.0 1.6 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 RLN50124.1 - 5.3e-06 26.3 1.5 5.3e-06 26.3 1.5 2.1 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 RLN50124.1 - 1e-05 25.3 2.3 1e-05 25.3 2.3 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 RLN50124.1 - 0.005 16.6 2.2 0.01 15.6 2.2 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger FYVE PF01363.21 RLN50124.1 - 0.0074 16.4 1.0 0.0074 16.4 1.0 2.2 3 0 0 3 3 3 1 FYVE zinc finger zf-CCCH_2 PF14608.6 RLN50124.1 - 0.031 14.8 0.8 0.072 13.6 0.8 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Zn_ribbon_recom PF13408.6 RLN50124.1 - 5 7.7 10.4 0.26 11.8 3.5 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Pkinase PF00069.25 RLN50125.1 - 7.5e-60 202.5 0.0 2.2e-40 138.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN50125.1 - 2.3e-28 99.2 0.0 1e-23 84.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase cNMP_binding PF00027.29 RLN50125.1 - 1.2e-21 76.5 0.0 1e-12 47.9 0.0 3.8 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 RLN50125.1 - 5.5e-08 32.5 0.0 9.5e-05 21.8 0.0 2.6 2 1 0 2 2 2 2 Kinase-like APH PF01636.23 RLN50125.1 - 1.9e-05 24.7 0.4 4.2e-05 23.6 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN50125.1 - 5.4e-05 22.6 0.0 0.00012 21.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN50125.1 - 0.00017 20.5 0.0 0.00029 19.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 RLN50125.1 - 0.0021 17.7 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 RLN50125.1 - 0.006 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Cupin_2 PF07883.11 RLN50125.1 - 0.18 11.5 0.4 8.3 6.2 0.0 2.6 2 0 0 2 2 2 0 Cupin domain Cellulase PF00150.18 RLN50126.1 - 1e-18 67.8 0.1 1.3e-18 67.4 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) UQ_con PF00179.26 RLN50127.1 - 0.037 13.7 0.4 0.15 11.7 0.4 2.0 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme CDC45 PF02724.14 RLN50132.1 - 0.66 8.2 3.0 0.7 8.1 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein EF-hand_6 PF13405.6 RLN50136.1 - 4.7e-11 41.7 0.1 0.076 13.0 0.0 6.6 7 0 0 7 7 7 2 EF-hand domain EF-hand_7 PF13499.6 RLN50136.1 - 3.8e-08 33.7 0.0 1.4 9.4 0.0 5.8 5 1 0 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.32 RLN50136.1 - 8.1e-08 31.3 0.0 0.77 9.5 0.0 5.5 6 0 0 6 6 6 3 EF hand EF-hand_5 PF13202.6 RLN50136.1 - 0.00039 19.8 0.1 0.71 9.5 0.1 3.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RLN50136.1 - 0.0024 17.7 0.1 7 6.6 0.0 4.9 6 0 0 6 6 6 1 EF-hand domain pair TMF_TATA_bd PF12325.8 RLN50136.1 - 0.14 12.4 0.5 0.46 10.7 0.5 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding PTEN_C2 PF10409.9 RLN50137.1 - 2.7e-08 33.6 0.0 3.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein BLOC1_2 PF10046.9 RLN50145.1 - 0.0023 18.2 2.7 0.0065 16.7 1.1 2.1 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2252 PF10009.9 RLN50145.1 - 0.025 13.7 0.3 0.032 13.3 0.3 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF2316 PF10078.9 RLN50145.1 - 0.085 13.1 0.5 0.14 12.4 0.5 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) Uso1_p115_C PF04871.13 RLN50145.1 - 0.094 13.1 6.7 0.13 12.6 6.7 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Syntaxin-6_N PF09177.11 RLN50145.1 - 1.1 9.8 6.6 0.92 10.1 3.8 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Glyco_hydro_19 PF00182.19 RLN50146.1 - 2.4e-49 168.3 3.0 3.6e-48 164.5 3.0 2.2 1 1 0 1 1 1 1 Chitinase class I ThiF PF00899.21 RLN50147.1 - 1.2e-62 211.5 0.1 1.8e-62 210.9 0.1 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 RLN50147.1 - 2.4e-20 72.4 0.0 4.5e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 RLN50147.1 - 0.0048 17.5 0.0 0.0091 16.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.20 RLN50147.1 - 0.031 14.3 0.1 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ecm33 PF12454.8 RLN50147.1 - 3.7 7.8 4.9 0.94 9.7 0.4 2.2 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein Palm_thioest PF02089.15 RLN50148.1 - 7.5e-24 84.9 1.3 8.8e-24 84.7 1.3 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Mobilization_B PF17511.2 RLN50161.1 - 0.017 15.5 0.7 0.024 15.0 0.7 1.2 1 0 0 1 1 1 0 Mobilization protein B DUF5484 PF17583.2 RLN50181.1 - 0.046 13.4 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5484) Fer2_3 PF13085.6 RLN50181.1 - 0.15 12.1 0.0 1.4 9.0 0.0 2.1 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain DUF5484 PF17583.2 RLN50183.1 - 0.063 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5484) Ssl1 PF04056.14 RLN50217.1 - 5e-64 215.7 0.0 6.5e-64 215.3 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 RLN50217.1 - 1.2e-11 44.6 21.9 1.5e-11 44.3 13.2 2.7 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 RLN50217.1 - 1.5e-08 35.2 0.0 2.6e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 RLN50217.1 - 0.00065 20.0 0.0 0.00087 19.6 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 RLN50217.1 - 0.0093 15.5 5.6 0.022 14.3 5.6 1.6 1 1 0 1 1 1 1 Transcription factor Tfb4 IBR PF01485.21 RLN50217.1 - 0.027 14.7 4.4 0.027 14.7 4.4 2.6 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain VWA_3 PF13768.6 RLN50217.1 - 0.16 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain TipAS PF07739.13 RLN50217.1 - 0.2 12.2 0.0 0.37 11.3 0.0 1.4 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain HTH_Tnp_Tc3_2 PF01498.18 RLN50218.1 - 0.00023 21.3 0.2 0.00096 19.3 0.0 2.2 2 1 0 2 2 2 1 Transposase HTH_Tnp_ISL3 PF13542.6 RLN50218.1 - 0.011 15.2 2.9 2.2 7.8 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 RLN50218.1 - 0.011 15.5 1.4 0.59 10.0 0.2 2.5 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 RLN50218.1 - 0.018 15.1 0.6 3.4 7.9 0.0 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_AraC PF00165.23 RLN50218.1 - 0.031 14.4 0.0 0.062 13.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_38 PF13936.6 RLN50218.1 - 0.094 12.5 0.4 0.41 10.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain C5HCH PF17982.1 RLN50218.1 - 0.15 12.3 0.0 0.4 10.9 0.0 1.7 1 0 0 1 1 1 0 NSD Cys-His rich domain AbiEi_4 PF13338.6 RLN50218.1 - 0.27 11.4 2.8 4.3 7.6 1.8 3.0 2 1 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin Patatin PF01734.22 RLN50219.1 - 1.4e-06 28.7 0.1 0.00036 20.8 0.1 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase 7tm_2 PF00002.24 RLN50220.1 - 0.0055 16.0 4.6 0.051 12.9 4.6 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 RLN50220.1 - 0.0087 15.2 3.5 0.022 13.9 3.5 1.7 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor Glu_synthase PF01645.17 RLN50225.1 - 9.3e-153 508.7 0.1 4.3e-150 499.9 0.0 2.2 2 0 0 2 2 2 2 Conserved region in glutamate synthase Glu_syn_central PF04898.14 RLN50225.1 - 6.7e-106 353.8 0.0 1.2e-105 353.0 0.0 1.4 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.19 RLN50225.1 - 1.9e-76 255.9 5.0 3.9e-76 254.9 5.0 1.5 1 0 0 1 1 1 1 GXGXG motif AAA_9 PF12781.7 RLN50225.1 - 0.016 14.4 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 ATP-binding dynein motor region FMN_dh PF01070.18 RLN50225.1 - 0.054 12.5 0.1 0.98 8.4 0.1 2.5 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Peptidase_C1 PF00112.23 RLN50226.1 - 2.6e-67 227.1 5.0 3.7e-67 226.6 5.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 RLN50226.1 - 4.4e-09 36.6 1.1 7.4e-09 35.9 1.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 RLN50226.1 - 5.9e-07 28.6 0.4 0.0031 16.3 0.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Rrp15p PF07890.12 RLN50227.1 - 4.7e-08 33.4 3.7 4.7e-08 33.4 3.7 1.9 2 0 0 2 2 2 1 Rrp15p Nop53 PF07767.11 RLN50227.1 - 0.0064 15.9 14.3 0.0075 15.7 14.3 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.12 RLN50227.1 - 2.9 6.0 18.0 3.9 5.6 18.0 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RLN50227.1 - 6.8 4.8 15.9 8.2 4.6 15.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Sox_N PF12444.8 RLN50227.1 - 7.3 7.8 9.1 2.5 9.3 4.7 2.1 2 0 0 2 2 2 0 Sox developmental protein N terminal FYVE_2 PF02318.16 RLN50229.1 - 0.29 11.4 4.6 0.27 11.5 2.6 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger FYVE PF01363.21 RLN50229.1 - 2.7 8.2 7.4 4.6 7.5 6.5 1.9 1 1 0 1 1 1 0 FYVE zinc finger FYVE PF01363.21 RLN50230.1 - 0.024 14.8 7.1 0.049 13.8 7.1 1.6 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN50230.1 - 0.5 10.6 7.9 0.92 9.7 7.0 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_UBOX PF13445.6 RLN50230.1 - 0.93 9.6 7.4 4.5 7.4 3.7 2.5 2 0 0 2 2 2 0 RING-type zinc-finger Zn-ribbon_8 PF09723.10 RLN50230.1 - 0.96 9.6 4.5 0.68 10.1 1.5 2.4 1 1 1 2 2 2 0 Zinc ribbon domain IBR PF01485.21 RLN50230.1 - 1.1 9.5 6.2 0.37 11.0 2.8 2.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain PDZ_6 PF17820.1 RLN50238.1 - 1.6e-10 40.7 0.8 1.1e-05 25.2 0.0 2.8 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 RLN50238.1 - 5e-10 39.6 0.0 3.2e-05 24.2 0.0 2.4 2 0 0 2 2 2 2 PDZ domain IMUP PF15761.5 RLN50238.1 - 0.47 11.2 4.5 1.2 9.8 4.5 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein Isochorismatase PF00857.20 RLN50245.1 - 3.8e-14 53.2 0.0 4.6e-13 49.7 0.0 2.2 1 1 0 1 1 1 1 Isochorismatase family PA PF02225.22 RLN50245.1 - 5.6e-11 42.3 0.2 1.7e-10 40.7 0.2 1.9 1 0 0 1 1 1 1 PA domain FAD-oxidase_C PF02913.19 RLN50245.1 - 0.043 13.4 0.6 0.11 12.1 0.6 1.6 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain DAO PF01266.24 RLN50245.1 - 0.63 9.5 5.4 0.72 9.4 4.2 1.7 2 1 0 2 2 2 0 FAD dependent oxidoreductase Ank_4 PF13637.6 RLN50246.1 - 1.9e-12 47.5 3.9 5.2e-06 26.9 1.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN50246.1 - 6.7e-12 45.8 2.4 2.6e-11 43.9 0.2 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN50246.1 - 5.1e-11 42.6 2.7 6.2e-07 29.6 0.7 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) WW PF00397.26 RLN50246.1 - 6.5e-09 35.7 1.4 1.7e-08 34.4 1.4 1.7 1 0 0 1 1 1 1 WW domain Ank PF00023.30 RLN50246.1 - 1.7e-08 34.5 2.7 0.0037 17.6 0.3 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 RLN50246.1 - 6.8e-07 29.1 2.1 0.044 14.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat FTZ PF03867.14 RLN50246.1 - 0.051 13.1 1.1 0.06 12.9 0.1 1.5 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region EF-hand_7 PF13499.6 RLN50247.1 - 1.2e-13 51.2 1.3 1.3e-09 38.3 0.2 3.2 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN50247.1 - 1.4e-10 40.3 0.2 0.036 14.0 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 RLN50247.1 - 9.5e-10 37.3 0.0 0.0056 16.1 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 RLN50247.1 - 4.7e-09 36.0 0.0 3.3e-06 26.8 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN50247.1 - 0.00084 18.7 0.0 4 7.1 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 RLN50247.1 - 0.0034 17.7 0.0 0.048 14.0 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_11 PF08976.11 RLN50247.1 - 0.018 15.9 0.0 0.052 14.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain G-patch_2 PF12656.7 RLN50248.1 - 1.4e-15 57.1 0.5 5.3e-15 55.2 0.0 2.3 2 0 0 2 2 2 1 G-patch domain GDPD PF03009.17 RLN50251.1 - 4.1e-53 180.8 0.0 8.4e-53 179.7 0.0 1.5 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family CBM_20 PF00686.19 RLN50251.1 - 8.3e-13 48.1 0.0 1.8e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain cNMP_binding PF00027.29 RLN50251.1 - 1.3e-12 47.6 0.0 2.4e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain F5_F8_type_C PF00754.25 RLN50251.1 - 0.00011 22.3 0.0 0.0054 16.9 0.1 3.0 3 0 0 3 3 3 1 F5/8 type C domain RRM_1 PF00076.22 RLN50252.1 - 1.3e-14 53.7 0.8 2.7e-05 23.9 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RLN50252.1 - 0.038 13.9 0.1 3.5 7.6 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif Serinc PF03348.15 RLN50253.1 - 4.4e-12 45.6 5.7 1.8e-08 33.8 0.1 2.0 1 1 1 2 2 2 2 Serine incorporator (Serinc) NYD-SP28 PF14772.6 RLN50254.1 - 3.1e-28 97.8 9.9 3.1e-28 97.8 9.9 6.5 3 1 2 6 6 6 1 Sperm tail NYD-SP28_assoc PF14775.6 RLN50254.1 - 1.7e-19 69.7 0.4 1.7e-19 69.7 0.4 5.1 5 1 1 6 6 6 1 Sperm tail C-terminal domain Spt5-NGN PF03439.13 RLN50254.1 - 0.078 12.9 0.2 0.44 10.5 0.1 2.4 1 1 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section Flavodoxin_2 PF02525.17 RLN50254.1 - 1.7 8.3 11.1 0.038 13.7 1.3 3.0 2 1 1 3 3 3 0 Flavodoxin-like fold WD40 PF00400.32 RLN50256.1 - 1.4e-08 35.2 0.1 0.00062 20.5 0.0 4.0 4 1 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.8 RLN50256.1 - 0.015 14.0 0.0 0.023 13.4 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 RLN50256.1 - 0.041 14.2 0.0 6.8 7.1 0.0 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 RLN50256.1 - 0.16 10.7 0.0 5.9 5.5 0.0 2.1 1 1 0 2 2 2 0 Nup133 N terminal like DUF4604 PF15377.6 RLN50256.1 - 0.44 11.0 17.3 1.1 9.7 17.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) ARL2_Bind_BART PF11527.8 RLN50258.1 - 1.9e-15 57.0 0.0 5.3e-10 39.4 0.0 2.4 1 1 1 2 2 2 2 The ARF-like 2 binding protein BART DHHC PF01529.20 RLN50259.1 - 7.1e-29 100.6 7.5 7.1e-29 100.6 7.5 2.9 3 0 0 3 3 3 1 DHHC palmitoyltransferase GerA PF03323.13 RLN50259.1 - 0.19 10.2 0.1 0.29 9.5 0.1 1.2 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein DUF4056 PF13265.6 RLN50260.1 - 0.01 15.2 0.0 0.039 13.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4056) Shadoo PF14999.6 RLN50260.1 - 0.045 13.8 0.8 0.053 13.6 0.6 1.3 1 1 0 1 1 1 0 Shadow of prion protein, neuroprotective CCDC53 PF10152.9 RLN50261.1 - 1.8 8.9 6.4 0.81 10.1 2.8 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex FlxA PF14282.6 RLN50261.1 - 4 7.5 7.3 0.43 10.6 2.0 2.1 2 0 0 2 2 2 0 FlxA-like protein SDP_N PF12278.8 RLN50261.1 - 4.2 7.5 6.7 9.7 6.3 2.9 2.4 2 0 0 2 2 2 0 Sex determination protein N terminal DnaJ PF00226.31 RLN50264.1 - 1e-13 51.2 0.3 1.7e-12 47.3 0.3 2.6 1 1 0 1 1 1 1 DnaJ domain MPDZ_u10 PF16667.5 RLN50264.1 - 0.0047 17.8 1.9 0.026 15.4 1.9 2.3 1 0 0 1 1 1 1 Unstructured region 10 on multiple PDZ protein Mito_carr PF00153.27 RLN50265.1 - 8e-33 112.2 0.5 7.9e-19 67.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein AP_endonuc_2 PF01261.24 RLN50265.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.3 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF3918 PF13056.6 RLN50265.1 - 0.18 11.5 0.2 0.41 10.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Aminotran_5 PF00266.19 RLN50266.1 - 9.4e-59 199.2 0.9 1.7e-58 198.4 0.9 1.4 1 1 0 1 1 1 1 Aminotransferase class-V APG6 PF04111.12 RLN50267.1 - 1.3e-60 204.4 0.0 1.9e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 RLN50267.1 - 2.1e-12 47.7 2.4 2.1e-12 47.7 2.4 1.8 2 0 0 2 2 2 1 Apg6 coiled-coil region Peptidase_S10 PF00450.22 RLN50292.1 - 3.6e-72 244.1 4.1 4.8e-72 243.7 4.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 RLN50293.1 - 3.5e-105 352.8 0.6 5.4e-105 352.2 0.6 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 RLN50293.1 - 3.4e-05 24.6 1.1 0.014 16.0 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF2811 PF10929.8 RLN50293.1 - 0.024 14.9 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) Peptidase_S10 PF00450.22 RLN50294.1 - 7.5e-38 131.0 0.0 8.6e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 RLN50295.1 - 1.2e-116 390.5 0.0 1.5e-116 390.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 RLN50295.1 - 0.0031 18.2 0.1 0.067 13.8 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 RLN50295.1 - 0.063 12.7 0.0 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Peptidase_S10 PF00450.22 RLN50296.1 - 8.3e-21 74.9 0.0 9.1e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 RLN50297.1 - 1.3e-37 130.2 0.0 1.5e-37 130.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 RLN50298.1 - 1.3e-67 229.0 1.3 1.8e-67 228.6 1.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Pkinase PF00069.25 RLN50304.1 - 9.1e-41 140.0 0.0 1e-37 129.9 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Cyclin_N PF00134.23 RLN50304.1 - 8.9e-23 80.4 2.3 1.5e-22 79.7 2.3 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pkinase_Tyr PF07714.17 RLN50304.1 - 6.2e-10 38.8 0.0 9.3e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase F-box-like PF12937.7 RLN50304.1 - 1.8e-08 34.1 0.0 2.4e-07 30.5 0.0 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 RLN50304.1 - 0.0032 17.3 0.2 0.0098 15.8 0.2 1.8 1 0 0 1 1 1 1 F-box domain Kdo PF06293.14 RLN50304.1 - 0.055 12.8 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SNase PF00565.17 RLN50305.1 - 1e-21 77.4 0.0 5.7e-13 49.3 0.0 2.6 3 0 0 3 3 3 2 Staphylococcal nuclease homologue TUDOR PF00567.24 RLN50305.1 - 3e-17 62.8 0.0 4.3e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Tudor domain FKBP_C PF00254.28 RLN50306.1 - 2.8e-08 33.9 0.0 3.3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PITH PF06201.13 RLN50309.1 - 1.6e-12 47.9 0.0 7.9e-10 39.1 0.0 2.1 1 1 1 2 2 2 2 PITH domain DUF1779 PF08680.10 RLN50310.1 - 0.018 15.2 0.5 0.021 15.0 0.5 1.1 1 0 0 1 1 1 0 TATA-box binding YqzE PF14038.6 RLN50310.1 - 0.069 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 YqzE-like protein DUF4337 PF14235.6 RLN50310.1 - 0.32 11.1 5.1 0.4 10.8 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Peptidase_S49_N PF08496.10 RLN50310.1 - 0.33 11.0 5.2 0.44 10.6 5.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal GAS PF13851.6 RLN50311.1 - 0.0074 15.7 17.5 0.0074 15.7 17.5 4.3 3 1 1 4 4 4 1 Growth-arrest specific micro-tubule binding Shugoshin_N PF07558.11 RLN50311.1 - 0.062 13.2 6.6 0.77 9.7 0.3 3.0 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF948 PF06103.11 RLN50311.1 - 0.13 12.5 3.8 1.3 9.3 0.2 3.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.11 RLN50311.1 - 2.5 6.0 18.5 2.6 5.9 14.8 2.3 2 0 0 2 2 2 0 Prominin Zw10 PF06248.13 RLN50311.1 - 7.6 5.0 24.3 0.58 8.7 3.1 2.4 1 1 1 2 2 2 0 Centromere/kinetochore Zw10 SAYSvFN PF10260.9 RLN50313.1 - 0.048 13.6 0.4 0.43 10.5 1.2 2.2 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) DUF2721 PF11026.8 RLN50313.1 - 0.13 12.2 3.5 0.21 11.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Peptidase_C26 PF07722.13 RLN50316.1 - 1.5e-19 70.7 0.0 8.4e-18 64.9 0.0 2.2 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 RLN50316.1 - 6.3e-09 35.9 0.0 9.7e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 RLN50316.1 - 0.041 13.7 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 SNO glutamine amidotransferase family VMA21 PF09446.10 RLN50318.1 - 0.81 9.8 4.6 4.2 7.6 0.1 3.3 3 0 0 3 3 3 0 VMA21-like domain RSN1_TM PF13967.6 RLN50322.1 - 3.4e-33 114.6 2.3 3.7e-33 114.5 0.1 2.2 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport RSN1_7TM PF02714.15 RLN50322.1 - 8.8e-27 94.1 13.7 8.8e-27 94.1 13.7 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 RLN50322.1 - 7.9e-26 91.3 0.1 1e-16 61.7 0.0 2.3 1 1 1 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter MtN3_slv PF03083.16 RLN50323.1 - 2.3e-12 46.8 0.2 2.6e-12 46.6 0.2 1.1 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange ABC_membrane PF00664.23 RLN50324.1 - 8.4e-101 337.2 30.8 3.8e-53 180.9 5.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN50324.1 - 4e-69 231.4 0.0 7e-34 117.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN50324.1 - 1.6e-08 34.3 6.4 0.0018 17.8 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RLN50324.1 - 2.2e-08 33.7 0.6 0.0023 17.6 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN50324.1 - 9.1e-08 32.5 1.2 0.024 14.9 0.0 4.4 3 2 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 RLN50324.1 - 1.9e-07 30.6 0.0 0.014 14.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.6 RLN50324.1 - 2.5e-07 31.2 1.9 0.015 15.7 0.4 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 RLN50324.1 - 1.2e-05 25.2 0.0 0.1 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 RLN50324.1 - 3.4e-05 23.8 0.2 0.19 11.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 RLN50324.1 - 5.6e-05 23.1 1.3 0.99 9.2 0.1 3.7 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 RLN50324.1 - 6.2e-05 22.8 1.8 0.42 10.3 0.1 3.3 2 2 0 2 2 2 2 AAA domain DUF87 PF01935.17 RLN50324.1 - 0.00015 22.0 1.0 0.21 11.6 0.1 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain G-alpha PF00503.20 RLN50324.1 - 0.00026 20.3 0.0 0.52 9.4 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA PF00004.29 RLN50324.1 - 0.0003 21.2 0.1 0.78 10.2 0.1 3.6 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 RLN50324.1 - 0.00036 20.8 0.0 1.4 9.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.20 RLN50324.1 - 0.00053 19.9 0.0 0.86 9.5 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_18 PF13238.6 RLN50324.1 - 0.00088 19.8 0.0 1 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 RLN50324.1 - 0.00097 18.0 3.4 0.12 11.2 0.1 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 RLN50324.1 - 0.001 18.7 1.2 1.1 8.8 0.0 3.3 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.14 RLN50324.1 - 0.0014 18.6 0.3 2.4 8.1 0.0 3.6 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 RLN50324.1 - 0.0027 17.9 0.0 3.8 7.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 RLN50324.1 - 0.0031 16.7 0.0 2.8 7.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_7 PF12775.7 RLN50324.1 - 0.0033 16.9 0.0 2.3 7.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region SbcCD_C PF13558.6 RLN50324.1 - 0.0062 16.7 4.5 2.4 8.5 0.4 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 RLN50324.1 - 0.0064 16.2 0.0 3.4 7.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 RLN50324.1 - 0.011 15.9 0.1 6.9 6.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 RLN50324.1 - 0.019 14.4 0.9 5.3 6.3 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Ploopntkinase3 PF18751.1 RLN50324.1 - 0.023 14.6 0.0 10 6.0 0.0 2.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_23 PF13476.6 RLN50324.1 - 0.036 14.6 0.0 9.1 6.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 RLN50324.1 - 0.044 12.8 0.0 3.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DEAD PF00270.29 RLN50324.1 - 0.046 13.5 0.9 44 3.8 0.0 3.9 3 1 0 3 3 3 0 DEAD/DEAH box helicase ATP-synt_ab PF00006.25 RLN50324.1 - 0.12 12.0 0.0 10 5.7 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 RLN50324.1 - 0.31 10.9 3.6 15 5.5 0.0 3.3 4 0 0 4 4 4 0 NACHT domain DDE_3 PF13358.6 RLN50346.1 - 1.8e-05 24.6 0.1 2.6e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease NTF2 PF02136.20 RLN50353.1 - 7.4e-08 33.0 0.0 8.3e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Clr5 PF14420.6 RLN50353.1 - 0.12 12.6 0.2 1.4 9.2 0.0 2.0 1 1 1 2 2 2 0 Clr5 domain SNARE PF05739.19 RLN50354.1 - 0.00028 20.8 0.4 0.00028 20.8 0.4 2.0 2 0 0 2 2 2 1 SNARE domain GP41 PF00517.17 RLN50354.1 - 0.14 12.0 0.8 0.21 11.5 0.1 1.7 2 0 0 2 2 2 0 Retroviral envelope protein HEAT_2 PF13646.6 RLN50355.1 - 0.0081 16.5 12.7 0.051 14.0 1.6 4.6 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 RLN50355.1 - 3.8 8.1 6.9 5.3 7.7 0.2 3.9 4 0 0 4 4 4 0 HEAT-like repeat Beta_elim_lyase PF01212.21 RLN50356.1 - 7.5e-74 248.6 0.0 1.8e-58 198.2 0.0 2.0 2 0 0 2 2 2 2 Beta-eliminating lyase Aminotran_1_2 PF00155.21 RLN50356.1 - 0.00024 20.4 0.0 0.00037 19.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 RLN50356.1 - 0.0016 17.5 0.0 0.003 16.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Pyridoxal_deC PF00282.19 RLN50356.1 - 0.02 13.6 0.0 0.03 13.0 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Nop14 PF04147.12 RLN50357.1 - 0.18 10.0 8.7 0.27 9.4 8.7 1.2 1 0 0 1 1 1 0 Nop14-like family Cpta_toxin PF07254.12 RLN50358.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Membrane-bound toxin component of toxin-antitoxin system SURF2 PF05477.11 RLN50358.1 - 3.4 7.3 8.8 5.7 6.6 8.8 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Myb_Cef PF11831.8 RLN50370.1 - 4.5e-46 157.3 8.1 4.5e-46 157.3 8.1 3.8 4 0 0 4 4 4 2 pre-mRNA splicing factor component Sugar_tr PF00083.24 RLN50375.1 - 2.4e-98 330.0 24.4 2.7e-98 329.8 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN50375.1 - 1.5e-22 80.1 39.1 6.5e-16 58.2 10.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3410 PF11890.8 RLN50376.1 - 0.077 12.8 0.2 0.26 11.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) ECH_1 PF00378.20 RLN50377.1 - 1.3e-19 70.5 0.0 1.5e-19 70.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RLN50377.1 - 5.4e-13 49.1 0.0 6.2e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase RPAP2_Rtr1 PF04181.13 RLN50378.1 - 3e-12 46.7 0.2 6.6e-12 45.6 0.2 1.6 1 0 0 1 1 1 1 Rtr1/RPAP2 family ALP_N PF17989.1 RLN50378.1 - 0.04 14.1 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 Actin like proteins N terminal domain Pkinase PF00069.25 RLN50379.1 - 1.1e-16 61.0 0.2 7.2e-10 38.7 0.3 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN50379.1 - 1.6e-06 27.6 0.4 0.00033 20.0 0.2 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Arm PF00514.23 RLN50380.1 - 0.0002 21.3 0.2 0.42 10.7 0.2 2.4 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat TPR_16 PF13432.6 RLN50380.1 - 0.036 14.7 1.5 0.071 13.8 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Cu-oxidase_2 PF07731.14 RLN50418.1 - 2e-36 124.8 5.4 9.5e-29 99.9 1.5 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN50418.1 - 6.8e-33 113.2 1.6 5.7e-31 107.0 0.0 3.1 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 RLN50418.1 - 7.9e-26 91.1 0.0 3.1e-25 89.1 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase TMEM117 PF15113.6 RLN50422.1 - 3.2e-09 36.2 0.9 7e-09 35.1 0.9 1.6 1 0 0 1 1 1 1 TMEM117 protein family Ion_trans_2 PF07885.16 RLN50422.1 - 4.7e-09 36.1 1.5 4.7e-09 36.1 1.5 2.9 3 0 0 3 3 3 1 Ion channel Ion_trans PF00520.31 RLN50422.1 - 0.012 14.8 0.3 0.05 12.8 0.3 2.1 1 0 0 1 1 1 0 Ion transport protein FYVE PF01363.21 RLN50468.1 - 0.018 15.2 7.0 0.034 14.3 7.0 1.4 1 0 0 1 1 1 0 FYVE zinc finger PseudoU_synth_2 PF00849.22 RLN50469.1 - 1.2e-16 61.2 0.0 2e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Dimer_Tnp_hAT PF05699.14 RLN50474.1 - 1.4e-18 66.5 0.0 4.4e-18 64.8 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 RLN50474.1 - 0.04 13.8 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) DUF4718 PF15842.5 RLN50474.1 - 0.3 10.9 2.4 0.63 9.8 0.1 2.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4718) FG-GAP_2 PF14312.6 RLN50476.1 - 6.2e-12 45.6 0.8 2.2e-06 27.8 0.2 3.1 3 0 0 3 3 3 2 FG-GAP repeat Calx-beta PF03160.14 RLN50476.1 - 7.2e-10 38.9 0.0 6.3e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 Calx-beta domain SWC7 PF17330.2 RLN50476.1 - 0.26 11.4 0.0 0.45 10.6 0.0 1.3 1 0 0 1 1 1 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 DEP PF00610.21 RLN50477.1 - 1.8e-34 117.6 3.4 2e-17 63.0 0.4 2.5 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ADP_ribosyl_GH PF03747.14 RLN50477.1 - 1e-18 68.1 0.0 1.8e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase MIP PF00230.20 RLN50492.1 - 0.00029 20.6 0.2 0.00038 20.2 0.2 1.2 1 0 0 1 1 1 1 Major intrinsic protein DNA_primase_lrg PF04104.14 RLN50494.1 - 4.7e-76 255.7 0.2 1.5e-75 254.1 0.1 1.7 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit Sec1 PF00995.23 RLN50495.1 - 2.8e-89 300.9 0.3 6.9e-88 296.3 0.3 2.0 1 1 0 1 1 1 1 Sec1 family DrsE PF02635.15 RLN50495.1 - 0.012 16.0 0.0 0.032 14.6 0.0 1.7 1 0 0 1 1 1 0 DsrE/DsrF-like family NDC10_II PF16787.5 RLN50497.1 - 0.03 13.4 0.1 0.062 12.4 0.0 1.5 1 1 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 PMSR PF01625.21 RLN50498.1 - 6.3e-61 205.0 1.1 8.2e-61 204.7 1.1 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase PPR_3 PF13812.6 RLN50506.1 - 5.8e-31 106.4 3.9 0.0012 18.9 0.0 12.3 7 3 6 14 14 14 9 Pentatricopeptide repeat domain PPR_2 PF13041.6 RLN50506.1 - 2.9e-29 101.0 17.4 0.0031 17.7 0.0 14.5 6 4 10 16 16 16 9 PPR repeat family PPR_long PF17177.4 RLN50506.1 - 1.2e-26 93.4 11.6 5.6e-07 29.1 0.1 5.4 2 1 4 6 6 6 6 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 RLN50506.1 - 5.3e-26 89.0 18.2 1 9.8 0.0 16.8 18 0 0 18 18 18 7 PPR repeat PPR_1 PF12854.7 RLN50506.1 - 5.2e-07 29.3 0.1 0.083 12.6 0.0 5.0 4 0 0 4 4 4 2 PPR repeat COX5A PF02284.16 RLN50506.1 - 2.7e-05 24.1 1.3 1.2 9.2 0.0 4.2 4 0 0 4 4 4 2 Cytochrome c oxidase subunit Va OmdA PF13376.6 RLN50506.1 - 0.76 9.8 3.9 2.8 8.0 0.0 3.8 4 1 1 5 5 5 0 Bacteriocin-protection, YdeI or OmpD-Associated ABC2_membrane PF01061.24 RLN50507.1 - 2.1e-68 229.8 68.4 2.9e-39 134.7 23.1 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN50507.1 - 3.6e-34 118.2 0.2 6.7e-16 59.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 RLN50507.1 - 4.1e-09 36.0 43.1 1.3e-07 31.1 7.3 3.1 2 2 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 RLN50507.1 - 2.5e-08 34.0 0.6 0.0069 16.3 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 RLN50507.1 - 3.4e-07 30.4 0.9 0.06 13.1 0.0 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN50507.1 - 9.3e-07 29.4 0.5 0.011 16.1 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain PDR_CDR PF06422.12 RLN50507.1 - 1.6e-06 27.9 6.7 0.001 19.0 0.0 4.4 4 0 0 4 4 4 1 CDR ABC transporter AAA_25 PF13481.6 RLN50507.1 - 6.1e-06 25.9 0.1 0.053 13.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 RLN50507.1 - 1.3e-05 24.9 6.7 0.02 14.6 1.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN50507.1 - 2.4e-05 24.6 0.1 0.07 13.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 RLN50507.1 - 5e-05 22.7 0.8 0.007 15.7 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.6 RLN50507.1 - 0.00043 20.9 0.6 0.32 11.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 RLN50507.1 - 0.00093 18.7 1.0 0.53 9.7 0.1 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 RLN50507.1 - 0.0016 18.9 0.1 4.4 7.7 0.1 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 RLN50507.1 - 0.0018 18.0 0.2 0.85 9.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 RLN50507.1 - 0.0055 16.3 1.1 1.1 8.9 0.4 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.9 RLN50507.1 - 0.0065 15.3 0.4 1.1 8.0 0.0 2.3 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_24 PF13479.6 RLN50507.1 - 0.0068 16.2 0.1 2.5 7.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 RLN50507.1 - 0.0081 16.2 1.8 1.1 9.4 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 RLN50507.1 - 0.01 16.4 0.0 4.6 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 RLN50507.1 - 0.017 14.3 0.8 0.04 13.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 RLN50507.1 - 0.017 15.2 0.1 6.2 7.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 RLN50507.1 - 0.024 14.7 0.5 0.8 9.7 0.1 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 RLN50507.1 - 0.029 13.5 0.2 0.12 11.5 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit Roc PF08477.13 RLN50507.1 - 0.03 14.5 0.4 2.8 8.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PDR_assoc PF08370.11 RLN50507.1 - 0.046 13.5 8.7 0.096 12.4 1.0 3.6 3 0 0 3 3 3 0 Plant PDR ABC transporter associated TsaE PF02367.17 RLN50507.1 - 0.046 13.7 0.8 3.3 7.7 0.2 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 RLN50507.1 - 0.071 13.0 4.1 3.9 7.4 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 RLN50507.1 - 0.081 13.3 0.4 14 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 RLN50507.1 - 0.09 12.5 1.9 3.9 7.2 0.3 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 RLN50507.1 - 0.12 12.3 0.0 12 5.8 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain Ploopntkinase3 PF18751.1 RLN50507.1 - 0.19 11.6 0.3 2 8.3 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_17 PF13207.6 RLN50507.1 - 0.3 11.5 0.6 5 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RLN50507.1 - 0.5 10.6 3.3 37 4.5 1.3 3.0 3 0 0 3 3 3 0 AAA domain ADH_N PF08240.12 RLN50508.1 - 7.9e-27 93.3 2.6 1.6e-26 92.3 2.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN50508.1 - 4e-17 62.4 0.9 6.9e-17 61.6 0.9 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN50508.1 - 1.1e-05 26.4 0.1 1.8e-05 25.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN50508.1 - 0.0002 20.8 0.6 0.00085 18.7 0.2 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KR PF08659.10 RLN50508.1 - 0.053 13.4 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 KR domain AlaDh_PNT_C PF01262.21 RLN50508.1 - 0.094 12.0 1.1 0.15 11.3 1.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Dynamin_N PF00350.23 RLN50509.1 - 5.3e-36 124.2 0.0 6.8e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 RLN50509.1 - 6.1e-15 55.2 0.0 8.9e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 RLN50509.1 - 4.7e-08 33.1 0.1 9.5e-07 28.9 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 RLN50509.1 - 0.0089 16.5 0.0 0.025 15.1 0.0 1.7 2 0 0 2 2 2 1 ABC transporter Roc PF08477.13 RLN50509.1 - 0.011 15.9 0.0 0.92 9.7 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 RLN50509.1 - 0.027 14.2 0.1 0.053 13.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN50509.1 - 0.054 13.4 0.1 7.7 6.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase IIGP PF05049.13 RLN50509.1 - 0.064 12.3 0.0 3 6.8 0.0 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.18 RLN50509.1 - 0.075 12.6 0.3 6.7 6.2 0.0 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B GED PF02212.18 RLN50510.1 - 1.5e-09 37.8 0.2 3.1e-09 36.9 0.2 1.5 1 0 0 1 1 1 1 Dynamin GTPase effector domain Dynamin_M PF01031.20 RLN50510.1 - 7.4e-09 35.2 0.0 5.2e-08 32.4 0.0 2.2 3 0 0 3 3 3 1 Dynamin central region GED PF02212.18 RLN50511.1 - 2.6e-06 27.5 0.4 4.8e-06 26.6 0.4 1.4 1 0 0 1 1 1 1 Dynamin GTPase effector domain MetOD1 PF18546.1 RLN50511.1 - 0.018 15.0 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Metanogen output domain 1 Helitron_like_N PF14214.6 RLN50525.1 - 8.1e-10 39.2 0.0 1.3e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus BT1 PF03092.16 RLN50533.1 - 1.5e-37 129.0 11.7 5e-23 81.1 1.5 2.6 2 1 0 2 2 2 2 BT1 family Pkinase PF00069.25 RLN50534.1 - 4.1e-59 200.1 0.0 2.5e-58 197.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN50534.1 - 1.6e-32 112.8 0.0 1.3e-31 109.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN50534.1 - 3.3e-06 26.6 0.0 6.5e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN50534.1 - 6.4e-05 23.0 0.2 6.4e-05 23.0 0.2 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RLN50534.1 - 0.00021 20.7 0.2 0.001 18.4 0.2 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RLN50534.1 - 0.0015 17.3 0.2 0.0037 16.1 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 RLN50534.1 - 0.013 14.5 0.0 0.029 13.3 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Glyco_hydro_72 PF03198.14 RLN50535.1 - 2.2e-112 375.4 11.6 1.3e-56 192.2 2.6 2.2 2 0 0 2 2 2 2 Glucanosyltransferase DegT_DnrJ_EryC1 PF01041.17 RLN50536.1 - 4.2e-26 92.1 0.0 6.5e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 RLN50536.1 - 6.1e-06 25.4 0.0 7.5e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 RLN50536.1 - 0.0048 16.1 0.0 0.0067 15.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II PHD PF00628.29 RLN50537.1 - 4e-08 33.0 7.2 4e-08 33.0 7.2 1.9 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.22 RLN50537.1 - 0.0044 16.9 1.0 0.0044 16.9 1.0 1.9 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF5320 PF17253.2 RLN50537.1 - 0.24 12.5 3.0 1.4 10.0 3.0 2.4 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Prok-RING_1 PF14446.6 RLN50537.1 - 0.7 9.9 7.3 1.3 9.0 4.3 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Auto_anti-p27 PF06677.12 RLN50537.1 - 2.2 8.5 10.2 2.3 8.5 0.1 3.3 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Activator_LAG-3 PF11498.8 RLN50537.1 - 2.5 7.0 15.5 3.6 6.4 15.0 1.5 1 1 0 1 1 1 0 Transcriptional activator LAG-3 zf-RING_2 PF13639.6 RLN50537.1 - 3.8 7.9 7.3 12 6.4 7.3 1.9 1 0 0 1 1 1 0 Ring finger domain GATA PF00320.27 RLN50537.1 - 4 7.1 12.8 0.17 11.5 6.4 2.2 2 0 0 2 2 2 0 GATA zinc finger PHD_2 PF13831.6 RLN50537.1 - 9.4 5.9 8.8 0.18 11.4 1.0 2.2 3 0 0 3 3 3 0 PHD-finger PHD_Oberon PF07227.11 RLN50537.1 - 10 6.0 11.4 0.4 10.6 5.0 2.0 3 0 0 3 3 3 0 PHD - plant homeodomain finger protein Anoctamin PF04547.12 RLN50538.1 - 2e-122 409.3 0.6 2.6e-122 408.9 0.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel RseC_MucC PF04246.12 RLN50542.1 - 0.88 9.5 5.5 20 5.1 0.7 3.8 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DUF2489 PF10675.9 RLN50542.1 - 1 9.3 3.4 2.4 8.1 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) PH PF00169.29 RLN50543.1 - 0.018 15.6 0.0 0.02 15.4 0.0 1.1 1 0 0 1 1 1 0 PH domain Neuroparsin PF07327.11 RLN50543.1 - 0.092 13.2 0.0 0.1 13.1 0.0 1.1 1 0 0 1 1 1 0 Neuroparsin Pkinase PF00069.25 RLN50545.1 - 9.8e-48 162.8 0.0 1.2e-47 162.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN50545.1 - 7.4e-27 94.3 0.0 1.1e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN50545.1 - 0.0073 15.1 0.0 0.0097 14.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN50545.1 - 0.086 12.8 0.1 0.22 11.4 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 RLN50545.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Syntaxin_2 PF14523.6 RLN50550.1 - 0.0054 17.1 2.4 0.0054 17.1 2.4 1.7 2 0 0 2 2 2 1 Syntaxin-like protein HAP1_N PF04849.13 RLN50550.1 - 0.024 13.9 5.5 0.034 13.4 5.5 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region FapA PF03961.13 RLN50550.1 - 0.03 12.9 0.3 0.038 12.6 0.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4515 PF14988.6 RLN50550.1 - 0.038 13.8 4.5 0.076 12.8 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) UPF0449 PF15136.6 RLN50550.1 - 0.042 14.3 0.7 0.042 14.3 0.7 2.3 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 CorA PF01544.18 RLN50550.1 - 0.052 12.8 3.8 0.082 12.2 3.8 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TPR_MLP1_2 PF07926.12 RLN50550.1 - 0.056 13.5 7.6 0.13 12.4 7.6 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.19 RLN50550.1 - 0.071 11.0 1.0 0.07 11.0 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Bap31_Bap29_C PF18035.1 RLN50550.1 - 0.086 12.9 0.4 0.22 11.5 0.2 1.8 1 1 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain CCDC-167 PF15188.6 RLN50550.1 - 0.12 12.7 6.0 0.21 11.9 6.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 GAS PF13851.6 RLN50550.1 - 0.2 11.0 7.4 0.32 10.3 7.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SKA2 PF16740.5 RLN50550.1 - 0.27 11.0 6.8 0.99 9.2 6.2 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Baculo_PEP_C PF04513.12 RLN50550.1 - 0.3 11.1 5.0 0.46 10.5 5.0 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cep57_CLD_2 PF14197.6 RLN50550.1 - 0.3 11.2 10.0 36 4.5 9.9 2.5 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Spc7 PF08317.11 RLN50550.1 - 0.33 9.8 9.5 0.49 9.2 9.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein OmpH PF03938.14 RLN50550.1 - 0.51 10.7 3.3 1.5 9.1 3.3 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) bZIP_1 PF00170.21 RLN50550.1 - 0.54 10.4 5.3 2.4 8.3 0.4 2.5 1 1 1 2 2 2 0 bZIP transcription factor HIP1_clath_bdg PF16515.5 RLN50550.1 - 0.54 10.9 9.7 1.2 9.8 9.7 1.6 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TSC22 PF01166.18 RLN50550.1 - 0.56 10.5 7.1 2.1 8.7 1.0 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family FlaC_arch PF05377.11 RLN50550.1 - 0.59 10.6 4.5 4.8 7.6 0.7 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) GIT1_C PF12205.8 RLN50550.1 - 0.77 9.9 7.6 2.8 8.1 6.5 2.3 2 1 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term Spc24 PF08286.11 RLN50550.1 - 0.92 9.8 10.9 1.7 8.9 2.1 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 CENP-H PF05837.12 RLN50550.1 - 0.99 9.8 9.5 2.2 8.7 9.5 1.7 1 1 0 1 1 1 0 Centromere protein H (CENP-H) JIP_LZII PF16471.5 RLN50550.1 - 1.1 9.4 6.8 5.1 7.3 6.4 2.0 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II ZapB PF06005.12 RLN50550.1 - 2.7 8.5 11.7 2.1 8.8 3.1 2.2 1 1 1 2 2 2 0 Cell division protein ZapB SlyX PF04102.12 RLN50550.1 - 3 8.5 8.0 8.1 7.2 1.5 3.2 2 1 1 3 3 3 0 SlyX DUF3450 PF11932.8 RLN50550.1 - 3.8 6.7 9.7 2.9 7.1 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) HALZ PF02183.18 RLN50550.1 - 3.9 7.8 4.9 44 4.4 0.4 2.7 2 1 0 2 2 2 0 Homeobox associated leucine zipper HalX PF08663.10 RLN50550.1 - 4.3 7.7 7.5 1.2 9.4 3.2 2.1 1 1 1 2 2 2 0 HalX domain YabA PF06156.13 RLN50550.1 - 8.2 7.1 7.7 1.2e+02 3.4 7.7 2.3 1 1 0 1 1 1 0 Initiation control protein YabA Csm1_N PF18504.1 RLN50550.1 - 8.5 6.8 8.5 2 8.8 2.3 2.2 1 1 1 2 2 2 0 Csm1 N-terminal domain WW PF00397.26 RLN50551.1 - 4.3e-10 39.5 0.0 7.3e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 WW domain TPD52 PF04201.15 RLN50562.1 - 0.33 10.5 5.3 0.1 12.2 1.9 1.8 2 0 0 2 2 2 0 Tumour protein D52 family Neur_chan_memb PF02932.16 RLN50562.1 - 0.42 10.6 5.3 0.72 9.9 5.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TBP PF00352.21 RLN50563.1 - 3.5e-34 116.6 0.1 4.7e-19 68.1 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) FliS_cochap PF16522.5 RLN50563.1 - 0.082 12.8 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Flagellar FLiS export co-chaperone, HP1076 DUF3378 PF11858.8 RLN50563.1 - 0.14 12.3 0.0 1.4 9.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3378) HECT PF00632.25 RLN50575.1 - 1.7e-36 126.3 0.1 2.1e-36 126.0 0.1 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Adaptin_N PF01602.20 RLN50576.1 - 4.4e-53 180.6 0.0 6.2e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region AP4E_app_platf PF14807.6 RLN50576.1 - 3.5e-26 91.5 0.0 5.8e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform Cnd1 PF12717.7 RLN50576.1 - 0.0015 18.6 0.0 0.0072 16.4 0.0 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 RLN50576.1 - 0.24 11.9 2.2 5.1 7.7 0.0 3.5 3 0 0 3 3 3 0 HEAT-like repeat PX PF00787.24 RLN50577.1 - 4.3e-07 29.9 0.1 1.1e-06 28.6 0.0 1.7 2 0 0 2 2 2 1 PX domain Sugar_tr PF00083.24 RLN50578.1 - 1.4e-36 126.4 10.7 1.5e-36 126.2 10.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN50578.1 - 1.9e-14 53.4 17.5 6.2e-14 51.7 17.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily BT1 PF03092.16 RLN50578.1 - 0.013 13.7 0.3 0.019 13.2 0.3 1.3 1 0 0 1 1 1 0 BT1 family MFS_2 PF13347.6 RLN50578.1 - 0.014 14.0 6.3 0.0097 14.5 4.3 1.6 1 1 0 1 1 1 0 MFS/sugar transport protein TRI12 PF06609.13 RLN50578.1 - 0.021 13.2 1.4 0.028 12.8 1.4 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) DUF4131 PF13567.6 RLN50578.1 - 1.3 8.7 3.8 4.1 7.0 2.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Biotin_carb_N PF00289.22 RLN50579.1 - 1e-45 154.8 0.1 1.3e-45 154.4 0.1 1.1 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain CoA_binding_3 PF13727.6 RLN50579.1 - 0.096 12.7 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 CoA-binding domain PRMT5_C PF17286.2 RLN50582.1 - 2.3e-13 50.4 0.0 5e-11 42.8 0.0 2.3 1 1 1 2 2 2 2 PRMT5 oligomerisation domain Voltage_CLC PF00654.20 RLN50585.1 - 8.3e-66 222.6 24.3 1.4e-65 221.9 24.3 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 RLN50585.1 - 0.071 13.6 0.0 0.39 11.2 0.0 2.3 2 0 0 2 2 2 0 CBS domain AAA PF00004.29 RLN50586.1 - 2.3e-49 167.2 0.0 3.1e-33 115.0 0.0 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN50586.1 - 5.3e-15 56.2 3.8 9.9e-06 26.0 0.1 4.1 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 RLN50586.1 - 1.5e-12 48.0 1.3 2.6e-05 24.5 0.3 4.4 2 2 0 2 2 2 2 AAA domain NACHT PF05729.12 RLN50586.1 - 2.4e-09 37.4 0.3 2.6e-05 24.2 0.0 3.4 3 1 0 3 3 3 2 NACHT domain AAA_25 PF13481.6 RLN50586.1 - 1.1e-07 31.6 5.4 0.13 11.8 0.1 4.6 3 2 2 5 5 4 2 AAA domain AAA_33 PF13671.6 RLN50586.1 - 2.9e-07 30.7 0.0 0.031 14.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 RLN50586.1 - 2.2e-06 28.2 0.0 0.0036 17.8 0.0 3.1 2 1 0 3 3 2 1 ABC transporter AAA_5 PF07728.14 RLN50586.1 - 2.3e-06 27.7 0.2 0.026 14.5 0.0 3.2 2 2 1 3 3 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 RLN50586.1 - 3.5e-06 27.3 0.0 0.11 12.9 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 RLN50586.1 - 7.4e-06 26.0 0.0 0.049 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 RLN50586.1 - 8.7e-06 25.8 0.0 0.0087 16.0 0.0 2.3 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea RuvB_N PF05496.12 RLN50586.1 - 2e-05 24.4 0.0 0.00011 21.9 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 RLN50586.1 - 3.1e-05 23.8 0.0 0.033 13.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_24 PF13479.6 RLN50586.1 - 3.3e-05 23.7 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 RLN50586.1 - 4.6e-05 23.4 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 RLN50586.1 - 7.4e-05 22.6 0.0 0.08 12.7 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 RLN50586.1 - 9.3e-05 21.8 0.0 0.38 10.0 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin AAA_29 PF13555.6 RLN50586.1 - 0.0001 22.0 0.1 0.03 14.1 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 RLN50586.1 - 0.00038 21.0 0.0 0.37 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 RLN50586.1 - 0.00056 19.7 0.0 0.78 9.6 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain TIP49 PF06068.13 RLN50586.1 - 0.00061 19.1 0.0 0.032 13.5 0.0 2.4 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_17 PF13207.6 RLN50586.1 - 0.00066 20.1 0.3 0.25 11.8 0.0 3.1 4 0 0 4 4 2 1 AAA domain DUF815 PF05673.13 RLN50586.1 - 0.0011 18.3 0.0 0.071 12.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 RLN50586.1 - 0.0011 18.2 0.0 0.77 8.9 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_23 PF13476.6 RLN50586.1 - 0.0012 19.4 0.0 0.063 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RLN50586.1 - 0.0015 18.0 0.0 0.78 9.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 RLN50586.1 - 0.0016 18.2 0.6 0.13 12.0 0.0 3.1 4 0 0 4 4 3 1 AAA domain Mg_chelatase PF01078.21 RLN50586.1 - 0.002 17.6 0.3 0.056 12.8 0.1 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 RLN50586.1 - 0.0023 17.3 0.3 0.013 14.9 0.0 2.3 2 1 1 3 3 3 1 FtsK/SpoIIIE family AAA_2 PF07724.14 RLN50586.1 - 0.0025 17.9 0.0 0.031 14.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF2075 PF09848.9 RLN50586.1 - 0.0032 16.8 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 RLN50586.1 - 0.0047 17.2 0.0 0.34 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain DAP3 PF10236.9 RLN50586.1 - 0.0056 15.9 0.0 3.3 6.8 0.0 2.6 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 Sigma54_activat PF00158.26 RLN50586.1 - 0.0073 16.0 0.0 3.6 7.3 0.0 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.6 RLN50586.1 - 0.0098 16.2 0.4 12 6.2 0.1 3.4 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.11 RLN50586.1 - 0.014 15.3 0.0 1.4 8.7 0.0 3.0 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 RLN50586.1 - 0.02 14.0 0.0 0.4 9.7 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein KAP_NTPase PF07693.14 RLN50586.1 - 0.02 14.1 0.0 7 5.8 0.0 3.1 2 1 1 3 3 3 0 KAP family P-loop domain MMR_HSR1 PF01926.23 RLN50586.1 - 0.022 14.8 0.1 0.19 11.9 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 RLN50586.1 - 0.026 14.4 0.0 6.1 6.7 0.0 2.5 2 0 0 2 2 2 0 NTPase Rad17 PF03215.15 RLN50586.1 - 0.047 13.6 0.2 0.95 9.4 0.0 2.7 3 1 0 3 3 2 0 Rad17 P-loop domain cobW PF02492.19 RLN50586.1 - 0.062 12.9 1.5 3.2 7.3 0.1 3.2 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.15 RLN50586.1 - 0.065 12.0 0.1 0.39 9.4 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_11 PF13086.6 RLN50586.1 - 0.082 12.7 0.0 9.8 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 RLN50586.1 - 0.095 12.5 0.5 2.6 7.7 0.0 3.1 3 1 1 4 4 3 0 Conserved hypothetical ATP binding protein Hist_deacetyl PF00850.19 RLN50591.1 - 1.1e-15 57.9 0.0 1e-11 44.9 0.0 2.1 2 0 0 2 2 2 2 Histone deacetylase domain Ank_2 PF12796.7 RLN50592.1 - 3.9e-56 187.6 4.8 5e-13 49.5 0.0 5.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Pkinase PF00069.25 RLN50592.1 - 6.4e-53 179.8 0.0 4.9e-41 140.8 0.0 3.3 4 1 0 4 4 4 2 Protein kinase domain Ank_4 PF13637.6 RLN50592.1 - 1.8e-52 175.1 5.6 1.4e-09 38.3 0.0 7.3 1 1 6 8 8 8 8 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 RLN50592.1 - 8.6e-49 166.1 0.0 1.9e-39 135.5 0.0 3.5 2 1 0 2 2 2 2 Protein tyrosine kinase Ank PF00023.30 RLN50592.1 - 2.4e-38 128.9 15.5 1.4e-05 25.3 0.0 10.2 10 0 0 10 10 10 7 Ankyrin repeat Ank_3 PF13606.6 RLN50592.1 - 8.9e-36 117.9 1.2 0.0019 18.5 0.0 10.7 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 RLN50592.1 - 3.7e-35 119.5 6.7 5.8e-08 32.8 0.0 8.9 1 1 8 9 9 9 8 Ankyrin repeats (many copies) Pkinase_fungal PF17667.1 RLN50592.1 - 0.0015 17.4 0.0 0.0037 16.1 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN50592.1 - 0.018 14.9 1.0 0.046 13.6 0.2 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 RLN50592.1 - 0.047 13.3 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family ParD_antitoxin PF03693.14 RLN50629.1 - 0.0057 17.0 0.8 0.17 12.3 0.0 2.6 2 0 0 2 2 2 1 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH ATG16 PF08614.11 RLN50629.1 - 0.0077 16.5 23.9 0.083 13.1 10.7 2.3 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Collagen PF01391.18 RLN50629.1 - 0.01 15.6 3.1 0.02 14.7 3.1 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Csm1_N PF18504.1 RLN50629.1 - 0.033 14.5 2.0 0.24 11.7 0.1 2.7 2 1 1 3 3 3 0 Csm1 N-terminal domain Filament PF00038.21 RLN50629.1 - 0.035 13.7 9.6 0.032 13.8 4.1 2.1 1 1 0 2 2 2 0 Intermediate filament protein PKcGMP_CC PF16808.5 RLN50629.1 - 0.059 13.2 3.4 0.62 10.0 0.1 3.0 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TPD52 PF04201.15 RLN50629.1 - 0.2 11.3 5.6 0.21 11.2 0.2 2.9 1 1 1 3 3 3 0 Tumour protein D52 family GAS PF13851.6 RLN50629.1 - 0.25 10.7 7.8 0.27 10.5 5.3 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 RLN50629.1 - 0.41 10.7 5.4 25 5.0 0.0 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4201 PF13870.6 RLN50629.1 - 0.51 10.0 6.2 1.8 8.2 0.2 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF641 PF04859.12 RLN50629.1 - 0.75 10.1 9.6 5.7 7.3 0.3 3.5 1 1 3 4 4 4 0 Plant protein of unknown function (DUF641) MscS_porin PF12795.7 RLN50629.1 - 0.87 9.1 21.2 1.1 8.7 18.9 2.2 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain FmiP_Thoc5 PF09766.9 RLN50629.1 - 0.91 8.7 4.8 0.2 10.9 1.0 1.7 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 Cep57_CLD_2 PF14197.6 RLN50629.1 - 1 9.5 11.3 0.4 10.8 0.8 3.8 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 Fez1 PF06818.15 RLN50629.1 - 2.2 8.7 11.8 3.9 7.9 11.1 1.7 1 1 0 1 1 1 0 Fez1 PRKG1_interact PF15898.5 RLN50629.1 - 6.3 7.8 14.2 3.5 8.6 5.0 2.6 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 RLN50629.1 - 7.2 7.1 16.4 0.41 11.2 6.9 2.6 1 1 2 3 3 3 0 Apg6 coiled-coil region Spc7 PF08317.11 RLN50629.1 - 7.6 5.3 11.6 0.51 9.2 2.9 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein PriC PF07445.12 RLN50640.1 - 0.00055 19.9 9.3 0.00055 19.9 9.3 2.4 2 0 0 2 2 2 1 Primosomal replication protein priC polyprenyl_synt PF00348.17 RLN50641.1 - 6.2e-58 195.9 0.0 1.8e-51 174.7 0.0 2.2 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 RLN50641.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 FGE-sulfatase PF03781.16 RLN50642.1 - 4.1e-21 75.7 0.1 8.6e-21 74.7 0.1 1.6 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 RLN50642.1 - 1.5e-06 28.7 0.6 3.6e-06 27.5 0.6 1.7 1 0 0 1 1 1 1 DinB superfamily NAD_binding_10 PF13460.6 RLN50643.1 - 2.4e-17 63.4 0.6 2.3e-12 47.2 1.7 2.7 2 0 0 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 RLN50643.1 - 1.5e-11 44.3 0.0 1.1e-06 28.4 0.2 3.3 3 0 0 3 3 3 2 NmrA-like family adh_short PF00106.25 RLN50643.1 - 0.018 14.5 1.0 0.73 9.3 0.2 2.4 2 0 0 2 2 2 0 short chain dehydrogenase DapB_N PF01113.20 RLN50643.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus HgmA PF04209.13 RLN50643.1 - 0.16 10.6 0.1 0.25 10.0 0.1 1.2 1 0 0 1 1 1 0 homogentisate 1,2-dioxygenase Epimerase PF01370.21 RLN50643.1 - 0.18 11.2 0.1 1.1 8.6 0.1 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family UCR_14kD PF02271.16 RLN50643.1 - 0.76 9.8 2.2 10 6.2 0.1 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Pyr_redox_2 PF07992.14 RLN50644.1 - 2.3e-47 161.7 1.7 1.6e-46 158.9 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 RLN50644.1 - 1.2e-24 86.7 1.0 4.7e-24 84.8 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 RLN50644.1 - 6.3e-17 61.9 1.5 1.6e-12 47.8 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RLN50644.1 - 1.2e-07 31.9 0.4 0.00015 21.9 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 RLN50644.1 - 2.7e-07 30.3 0.0 4.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 RLN50644.1 - 3e-07 30.0 0.0 0.0086 15.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 RLN50644.1 - 1.5e-05 24.3 0.8 1.5e-05 24.3 0.8 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 RLN50644.1 - 3.6e-05 22.7 4.8 0.00036 19.3 0.2 2.9 2 1 1 3 3 3 1 HI0933-like protein Thi4 PF01946.17 RLN50644.1 - 3.9e-05 23.0 0.2 0.001 18.4 0.0 2.3 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.18 RLN50644.1 - 0.00013 21.9 0.1 0.02 14.8 0.0 2.9 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN50644.1 - 0.0033 16.8 0.4 0.36 10.1 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 RLN50644.1 - 0.0067 15.5 0.9 1.7 7.6 0.3 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 RLN50644.1 - 0.011 15.3 7.5 0.062 12.9 0.1 3.4 3 1 1 4 4 4 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 RLN50644.1 - 0.032 13.4 0.0 5.9 5.9 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 RLN50644.1 - 0.15 11.1 2.8 0.19 10.7 0.1 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A Isy1 PF06246.12 RLN50645.1 - 4e-68 229.7 5.6 5.2e-68 229.4 5.6 1.0 1 0 0 1 1 1 1 Isy1-like splicing family Herpes_US12 PF05363.12 RLN50645.1 - 0.077 13.7 1.2 0.23 12.2 0.1 2.3 2 1 0 2 2 2 0 Herpesvirus US12 family DUF4598 PF15370.6 RLN50646.1 - 8.2e-18 64.9 4.1 1.2e-17 64.3 4.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) COX4 PF02936.14 RLN50646.1 - 0.00013 22.0 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DNA_pol_phi PF04931.13 RLN50646.1 - 9.5 4.2 7.8 12 3.9 7.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ank_2 PF12796.7 RLN50647.1 - 5.3e-11 43.0 0.0 0.00057 20.4 0.0 4.4 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN50647.1 - 8.6e-07 29.4 6.1 0.24 12.0 0.2 5.9 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN50647.1 - 2.7e-06 27.5 2.0 0.19 12.1 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN50647.1 - 0.00039 20.7 6.0 4.8 8.1 0.0 6.1 5 1 1 6 6 6 1 Ankyrin repeat Ank PF00023.30 RLN50647.1 - 0.0016 18.8 0.5 5.2 7.7 0.1 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ion_trans PF00520.31 RLN50647.1 - 0.72 9.0 17.9 2.7 7.1 17.9 2.0 1 1 0 1 1 1 0 Ion transport protein Na_H_Exchanger PF00999.21 RLN50648.1 - 7.6e-19 67.8 29.3 1.1e-18 67.2 29.3 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SBF PF01758.16 RLN50648.1 - 0.0061 16.3 11.0 0.01 15.5 6.3 2.6 2 0 0 2 2 2 1 Sodium Bile acid symporter family Dynein_light PF01221.18 RLN50649.1 - 3.9e-24 84.8 0.0 5.4e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 WWE PF02825.20 RLN50650.1 - 0.048 14.3 0.1 2 9.1 0.0 2.8 2 0 0 2 2 2 0 WWE domain Pkinase_Tyr PF07714.17 RLN50651.1 - 4.8e-45 153.9 0.0 4.1e-40 137.7 0.0 3.6 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 RLN50651.1 - 9.4e-41 139.9 0.0 2.2e-37 128.9 0.0 3.9 3 1 0 3 3 3 1 Protein kinase domain DUF5129 PF17173.4 RLN50651.1 - 0.0002 20.6 0.4 0.00047 19.4 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5129) APH PF01636.23 RLN50651.1 - 0.0067 16.4 0.2 0.0067 16.4 0.2 3.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family Ribosomal_S7e PF01251.18 RLN50651.1 - 0.01 15.6 0.1 0.018 14.8 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S7e DUF1090 PF06476.12 RLN50651.1 - 0.01 15.9 0.9 0.023 14.8 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) Pkinase_fungal PF17667.1 RLN50651.1 - 0.034 12.9 0.0 0.065 12.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Metallopep PF12044.8 RLN50652.1 - 1.8e-19 69.7 0.0 5.8e-12 44.9 0.0 2.2 2 0 0 2 2 2 2 Putative peptidase family Jacalin PF01419.17 RLN50652.1 - 7.3e-13 48.6 0.0 4.5e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 Jacalin-like lectin domain Glyco_tran_28_C PF04101.16 RLN50653.1 - 6.8e-24 84.7 0.0 7.9e-24 84.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain PSI_8 PF00796.18 RLN50654.1 - 1.8 8.5 2.9 3.4 7.6 2.9 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VIII Histone PF00125.24 RLN50657.1 - 8.8e-53 178.2 2.9 9.8e-53 178.0 2.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 RLN50657.1 - 0.00046 20.8 1.6 0.00056 20.5 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 RLN50657.1 - 0.00068 20.0 0.0 0.0011 19.4 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 RLN50657.1 - 0.0043 17.1 0.7 0.0059 16.7 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 RLN50657.1 - 0.0082 16.4 0.1 0.0082 16.4 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 RLN50657.1 - 0.044 13.9 0.3 0.069 13.2 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit FeS_assembly_P PF01883.19 RLN50658.1 - 1e-12 48.1 0.0 2.1e-12 47.0 0.0 1.6 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein PIGA PF08288.12 RLN50658.1 - 0.041 14.5 0.0 0.068 13.8 0.0 1.4 1 0 0 1 1 1 0 PIGA (GPI anchor biosynthesis) PP2C PF00481.21 RLN50660.1 - 1.5e-48 165.7 0.0 2e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C GST_N_3 PF13417.6 RLN50661.1 - 2.9e-16 59.6 0.0 4.7e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RLN50661.1 - 8.8e-15 54.8 0.0 1.7e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN50661.1 - 1.3e-11 44.6 0.0 2.7e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN50661.1 - 0.00019 21.4 0.1 0.014 15.4 0.1 2.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RLN50661.1 - 0.00032 20.8 0.0 0.0006 20.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 RLN50661.1 - 0.0011 19.2 0.0 0.0036 17.5 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin GST_C PF00043.25 RLN50661.1 - 0.0071 16.5 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HEAT_2 PF13646.6 RLN50671.1 - 5.6e-32 110.0 8.6 1.4e-14 54.2 0.4 3.2 2 2 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 RLN50671.1 - 3.3e-22 76.9 1.1 8.3e-05 22.9 0.1 6.1 6 0 0 6 6 6 4 PBS lyase HEAT-like repeat HEAT PF02985.22 RLN50671.1 - 9.7e-09 34.8 4.2 0.039 14.2 0.0 6.0 5 1 1 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 RLN50671.1 - 0.0014 19.1 3.0 0.4 11.3 0.2 3.5 2 2 1 3 3 3 2 HEAT-like repeat DUF3385 PF11865.8 RLN50671.1 - 0.002 18.1 0.1 3.6 7.5 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF3385) DUF4375 PF14300.6 RLN50671.1 - 0.038 14.2 0.1 39 4.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4375) Ribosomal_L29 PF00831.23 RLN50671.1 - 0.047 13.7 4.5 9.8 6.2 0.0 3.8 4 1 0 4 4 4 0 Ribosomal L29 protein Peptidase_S78 PF04586.17 RLN50671.1 - 0.052 13.7 0.2 2.7 8.1 0.0 2.7 2 1 1 3 3 3 0 Caudovirus prohead serine protease ubiquitin PF00240.23 RLN50672.1 - 5e-05 23.0 0.0 0.0012 18.6 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_4 PF18036.1 RLN50672.1 - 0.0097 15.9 0.0 0.017 15.1 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 RLN50672.1 - 0.048 13.5 0.0 0.066 13.0 0.0 1.1 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain TPR_22 PF18833.1 RLN50672.1 - 0.11 12.7 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat LSM PF01423.22 RLN50674.1 - 5.1e-17 61.3 0.2 1.1e-16 60.2 0.2 1.6 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RLN50674.1 - 0.014 15.6 0.0 0.046 13.9 0.0 1.9 1 0 0 1 1 1 0 Ataxin 2 SM domain Tail_tube PF10618.9 RLN50674.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Phage tail tube protein HECT_2 PF09814.9 RLN50680.1 - 1.9e-40 138.9 0.0 6.7e-40 137.1 0.0 1.8 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.14 RLN50680.1 - 0.019 15.2 0.2 1.6 9.0 0.0 3.1 3 0 0 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PX PF00787.24 RLN50681.1 - 9.9e-10 38.4 0.1 1.9e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 PX domain OTU PF02338.19 RLN50681.1 - 0.13 12.8 0.7 1.3 9.6 0.7 2.4 1 1 0 1 1 1 0 OTU-like cysteine protease Steroid_dh PF02544.16 RLN50682.1 - 9.9e-16 58.1 0.1 9.9e-16 58.1 0.1 2.1 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 RLN50682.1 - 0.0078 16.6 0.0 0.0078 16.6 0.0 2.7 4 0 0 4 4 4 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 RLN50682.1 - 0.012 14.4 1.2 0.012 14.4 0.2 1.5 2 0 0 2 2 2 0 Ergosterol biosynthesis ERG4/ERG24 family G10 PF01125.17 RLN50683.1 - 1.8e-54 183.5 3.8 4.4e-54 182.2 3.8 1.7 1 0 0 1 1 1 1 G10 protein BUD22 PF09073.10 RLN50683.1 - 0.44 9.8 25.9 0.6 9.4 25.9 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 RLN50683.1 - 1.2 7.4 17.2 1.6 6.9 17.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RLN50683.1 - 4.4 5.4 27.5 5.7 5.0 27.5 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 RLN50683.1 - 6.2 6.5 25.6 9.8 5.8 25.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.32 RLN50684.1 - 2e-24 85.3 8.0 1.5e-05 25.7 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN50684.1 - 3.2e-14 53.0 1.3 0.00069 19.9 0.2 4.6 3 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RLN50684.1 - 0.00045 20.2 0.0 0.0016 18.3 0.0 1.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 RLN50684.1 - 0.0064 15.5 0.0 0.035 13.1 0.0 2.0 1 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ABC_tran PF00005.27 RLN50687.1 - 4.6e-55 185.9 0.0 2.8e-30 105.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 RLN50687.1 - 1.7e-34 119.5 45.5 8e-19 67.9 11.3 3.9 4 0 0 4 4 4 2 ABC-2 family transporter protein AAA_21 PF13304.6 RLN50687.1 - 3.5e-16 59.9 1.1 2.7e-05 24.2 0.0 4.1 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 RLN50687.1 - 2e-05 24.7 0.1 0.77 10.0 0.0 4.5 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 RLN50687.1 - 0.00063 20.3 1.0 0.015 15.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 RLN50687.1 - 0.0017 17.8 3.6 0.92 8.9 0.0 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MukB PF04310.12 RLN50687.1 - 0.0018 18.1 3.3 0.72 9.6 0.4 2.6 2 0 0 2 2 2 2 MukB N-terminal AAA_29 PF13555.6 RLN50687.1 - 0.003 17.3 3.3 0.068 12.9 0.5 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 RLN50687.1 - 0.0095 15.7 0.0 0.79 9.4 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_16 PF13191.6 RLN50687.1 - 0.012 16.0 0.0 7.7 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 RLN50687.1 - 0.036 13.8 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 RLN50687.1 - 0.062 12.6 0.1 16 4.7 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin RsgA_GTPase PF03193.16 RLN50687.1 - 0.1 12.5 0.6 0.9 9.4 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase DUF87 PF01935.17 RLN50687.1 - 0.17 11.9 1.0 5.3 7.1 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain SRP54 PF00448.22 RLN50687.1 - 0.18 11.4 2.6 6.8 6.3 0.3 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 RLN50687.1 - 0.28 11.3 0.6 21 5.3 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arm PF00514.23 RLN50689.1 - 9.1e-24 82.7 20.1 1.5e-08 34.4 0.3 8.0 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 RLN50689.1 - 4.6e-10 38.9 0.0 1e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 RLN50689.1 - 1.1e-06 29.0 1.8 0.17 12.3 0.0 5.1 3 3 1 5 5 5 2 HEAT repeats IBB PF01749.20 RLN50689.1 - 3.1e-06 27.6 2.5 6.9e-06 26.4 1.0 2.1 2 0 0 2 2 2 1 Importin beta binding domain HEAT_EZ PF13513.6 RLN50689.1 - 1.3e-05 25.5 10.0 0.22 12.1 0.1 5.1 5 0 0 5 5 5 3 HEAT-like repeat Arm_2 PF04826.13 RLN50689.1 - 0.00053 19.5 0.1 0.13 11.7 0.1 3.1 3 0 0 3 3 3 1 Armadillo-like HEAT PF02985.22 RLN50689.1 - 0.024 14.8 8.4 2.8 8.4 0.0 6.1 7 0 0 7 7 7 0 HEAT repeat V-ATPase_H_C PF11698.8 RLN50689.1 - 0.04 14.0 0.1 2.5 8.2 0.0 2.7 2 0 0 2 2 2 0 V-ATPase subunit H HEAT_PBS PF03130.16 RLN50689.1 - 0.11 13.3 2.7 22 6.1 0.1 4.8 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Gtr1_RagA PF04670.12 RLN50694.1 - 1.6e-59 201.0 0.7 2e-59 200.8 0.7 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RLN50694.1 - 0.055 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Roc PF08477.13 RLN50694.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Syntaxin PF00804.25 RLN50695.1 - 4.3e-28 98.4 5.7 5.1e-27 94.9 2.8 2.6 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 RLN50695.1 - 1.6e-16 60.0 0.3 4.2e-16 58.7 0.3 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 RLN50695.1 - 0.001 19.4 1.8 0.001 19.4 1.8 2.3 2 1 0 2 2 2 1 Syntaxin-like protein PAH PF02671.21 RLN50695.1 - 0.019 15.1 1.3 0.08 13.1 1.3 2.0 1 0 0 1 1 1 0 Paired amphipathic helix repeat PXA PF02194.15 RLN50695.1 - 0.047 13.7 0.5 0.059 13.3 0.5 1.3 1 0 0 1 1 1 0 PXA domain LCE6A PF15858.5 RLN50695.1 - 0.085 13.6 0.0 0.21 12.4 0.0 1.6 1 0 0 1 1 1 0 Late cornified envelope protein 6A family Pepsin-I3 PF06394.13 RLN50695.1 - 0.11 12.7 0.8 0.24 11.6 0.3 1.8 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain YscO-like PF16789.5 RLN50695.1 - 2.7 8.0 11.7 1.7 8.7 5.5 2.4 2 1 0 2 2 2 0 YscO-like protein YabA PF06156.13 RLN50695.1 - 3.1 8.5 8.0 0.86 10.3 0.3 2.8 3 0 0 3 3 3 0 Initiation control protein YabA Med2 PF11214.8 RLN50695.1 - 7.6 6.8 9.2 4 7.6 0.2 2.9 3 0 0 3 3 3 0 Mediator complex subunit 2 CHCH PF06747.13 RLN50696.1 - 2e-08 34.1 4.0 3e-08 33.6 4.0 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 RLN50696.1 - 0.0023 17.9 2.9 0.0035 17.3 2.9 1.2 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, MTCP1 PF08991.10 RLN50696.1 - 0.025 14.8 2.1 0.044 14.0 2.1 1.4 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type COX6B PF02297.17 RLN50696.1 - 0.062 13.6 1.4 0.09 13.0 1.4 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 RLN50696.1 - 0.13 12.5 2.2 0.19 12.0 2.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 RLN50696.1 - 0.24 11.5 4.0 0.36 10.9 4.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like CBS PF00571.28 RLN50697.1 - 1.6e-17 63.7 0.1 2.9e-07 30.8 0.0 4.3 3 1 1 4 4 4 4 CBS domain DUF4213 PF13938.6 RLN50697.1 - 0.13 12.6 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 Putative heavy-metal chelation SVIP PF15811.5 RLN50698.1 - 1.8e-05 25.1 6.0 1.8e-05 25.1 6.0 2.1 2 0 0 2 2 2 1 Small VCP/p97-interacting protein PAS PF00989.25 RLN50701.1 - 6e-31 106.8 0.2 3.2e-12 46.4 0.0 3.1 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 RLN50701.1 - 1.3e-18 67.3 4.2 2.5e-09 37.4 0.1 3.0 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 RLN50701.1 - 4e-17 62.4 0.1 6.1e-08 32.9 0.0 3.1 3 0 0 3 3 3 2 PAS domain PAS_8 PF13188.7 RLN50701.1 - 3.1e-09 36.6 0.2 0.013 15.6 0.0 3.3 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 RLN50701.1 - 7.1e-06 26.2 0.0 0.00015 22.0 0.0 2.4 3 0 0 3 3 3 1 PAS fold PAS_10 PF13596.6 RLN50701.1 - 0.00033 21.2 0.0 0.75 10.4 0.0 2.9 3 0 0 3 3 3 2 PAS domain PAS_7 PF12860.7 RLN50701.1 - 0.0011 19.1 0.1 2.5 8.3 0.0 3.4 4 0 0 4 4 4 2 PAS fold MycE_N PF17843.1 RLN50701.1 - 0.07 13.6 9.7 0.43 11.1 0.6 2.3 2 0 0 2 2 2 0 MycE methyltransferase N-terminal Tae4 PF14113.6 RLN50701.1 - 0.1 12.9 0.0 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 Type VI secretion system (T6SS), amidase effector protein 4 PAS PF00989.25 RLN50702.1 - 5.9e-105 345.2 1.2 3.9e-20 71.9 0.0 5.3 5 0 0 5 5 5 5 PAS fold PAS_9 PF13426.7 RLN50702.1 - 2.8e-55 185.0 8.9 1.6e-10 41.2 0.0 6.0 6 0 0 6 6 6 5 PAS domain PAS_4 PF08448.10 RLN50702.1 - 1.4e-54 183.0 0.0 4.7e-13 49.3 0.0 5.8 5 0 0 5 5 5 5 PAS fold PAS_3 PF08447.12 RLN50702.1 - 4.8e-32 110.1 0.0 3.3e-07 30.5 0.0 5.4 5 0 0 5 5 5 5 PAS fold HATPase_c PF02518.26 RLN50702.1 - 6.3e-27 94.3 0.0 2.2e-26 92.5 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 RLN50702.1 - 1.4e-20 73.5 0.0 4.8e-20 71.8 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain PAS_8 PF13188.7 RLN50702.1 - 6.6e-18 64.3 0.2 0.008 16.2 0.0 5.5 5 0 0 5 5 5 5 PAS domain HisKA PF00512.25 RLN50702.1 - 6e-17 61.4 0.2 2.3e-16 59.6 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_10 PF13596.6 RLN50702.1 - 6.2e-10 39.6 0.8 0.034 14.8 0.0 5.4 5 0 0 5 5 5 2 PAS domain Hpt PF01627.23 RLN50702.1 - 2.1e-06 27.9 0.1 5.9e-06 26.5 0.1 1.8 1 0 0 1 1 1 1 Hpt domain PAS_7 PF12860.7 RLN50702.1 - 2.3e-06 27.7 5.7 0.24 11.6 0.1 6.4 5 4 0 5 5 5 1 PAS fold DUF5588 PF17826.1 RLN50702.1 - 0.13 11.1 0.1 7.9 5.3 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5588) WD40 PF00400.32 RLN50711.1 - 2.7e-16 59.6 35.0 8.3e-07 29.6 0.2 11.7 12 0 0 12 12 12 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN50711.1 - 1.7e-10 41.0 0.2 0.23 11.8 0.0 6.1 5 0 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Atg8 PF02991.16 RLN50712.1 - 4.4e-36 123.2 0.2 5.1e-36 123.0 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 RLN50712.1 - 8.3e-05 22.9 0.0 0.0001 22.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 GETHR PF05671.11 RLN50716.1 - 1.6e-13 49.8 66.8 0.058 12.8 2.6 9.5 1 1 8 9 9 9 8 GETHR pentapeptide repeat (5 copies) TPH PF13868.6 RLN50718.1 - 1.2e-17 63.5 130.3 1.2e-17 63.5 130.3 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain DUF4344 PF14247.6 RLN50719.1 - 0.047 13.3 0.3 12 5.4 0.0 2.8 1 1 2 3 3 3 0 Putative metallopeptidase Ion_trans PF00520.31 RLN50720.1 - 4.4e-42 144.0 29.0 1.6e-24 86.5 6.9 2.5 3 0 0 3 3 3 2 Ion transport protein Ion_trans_2 PF07885.16 RLN50720.1 - 2.4e-24 85.1 15.6 1.8e-14 53.5 2.2 3.4 4 0 0 4 4 4 2 Ion channel IRK PF01007.20 RLN50720.1 - 0.04 13.7 4.4 1.5 8.6 0.0 3.8 3 0 0 3 3 3 0 Inward rectifier potassium channel transmembrane domain PDT PF00800.18 RLN50721.1 - 1.3e-55 188.0 0.0 3.7e-55 186.6 0.0 1.8 2 0 0 2 2 2 1 Prephenate dehydratase PDH PF02153.17 RLN50721.1 - 1.3e-14 53.9 0.0 2.3e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 RLN50721.1 - 5.5e-07 30.1 0.0 1.9e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 RLN50721.1 - 0.018 14.4 0.0 0.044 13.2 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 RLN50721.1 - 0.041 14.1 0.0 0.074 13.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pkinase PF00069.25 RLN50731.1 - 6.1e-19 68.4 0.0 6.6e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN50731.1 - 5.4e-18 65.2 0.0 6.3e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase PAE PF03283.13 RLN50732.1 - 8.2e-16 58.1 1.5 1.8e-15 57.0 1.2 1.5 1 1 0 1 1 1 1 Pectinacetylesterase RVT_1 PF00078.27 RLN50738.1 - 1.7e-06 27.7 0.0 3.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AHSP PF09236.10 RLN50738.1 - 0.015 15.7 0.1 16 6.1 0.0 3.7 3 0 0 3 3 3 0 Alpha-haemoglobin stabilising protein Syntaxin_2 PF14523.6 RLN50738.1 - 1.7 9.0 5.1 20 5.7 0.9 3.2 2 0 0 2 2 2 0 Syntaxin-like protein HR1 PF02185.16 RLN50739.1 - 0.071 13.2 1.5 0.12 12.5 0.5 1.7 2 0 0 2 2 2 0 Hr1 repeat AIP3 PF03915.13 RLN50739.1 - 0.14 11.2 0.2 0.21 10.7 0.2 1.3 1 1 0 1 1 1 0 Actin interacting protein 3 DUF4442 PF14539.6 RLN50740.1 - 5.1e-32 110.8 0.1 5.9e-32 110.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) FLgD_tudor PF13861.6 RLN50740.1 - 0.084 13.1 0.0 0.11 12.8 0.0 1.4 1 1 0 1 1 1 0 FlgD Tudor-like domain Mucin PF01456.17 RLN50741.1 - 0.91 9.5 4.7 2.4 8.2 4.7 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Oxidored_q6 PF01058.22 RLN50742.1 - 5.5e-22 78.0 0.0 6.4e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Secapin PF17521.2 RLN50742.1 - 0.0044 16.8 0.5 0.026 14.3 0.0 2.0 2 0 0 2 2 2 1 Honey bee peptides Oxidored_q6 PF01058.22 RLN50743.1 - 2.1e-41 140.8 0.0 2e-20 73.0 0.0 2.7 2 0 0 2 2 2 2 NADH ubiquinone oxidoreductase, 20 Kd subunit Pkinase_Tyr PF07714.17 RLN50743.1 - 3.4e-23 82.2 0.0 1e-22 80.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RLN50743.1 - 4.5e-21 75.4 0.0 1.1e-20 74.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Secapin PF17521.2 RLN50743.1 - 0.00021 21.0 5.0 0.13 12.1 0.0 3.6 4 0 0 4 4 4 2 Honey bee peptides ABC1 PF03109.16 RLN50743.1 - 0.0065 16.6 0.0 0.023 14.8 0.0 1.9 2 0 0 2 2 2 1 ABC1 family Pox_F11 PF04943.12 RLN50743.1 - 0.0089 15.1 2.3 0.014 14.5 2.3 1.2 1 0 0 1 1 1 1 Poxvirus F11 protein Kdo PF06293.14 RLN50743.1 - 0.027 13.8 0.0 0.17 11.2 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DEC-1_C PF04626.13 RLN50743.1 - 0.072 13.5 6.6 2 8.8 0.8 2.5 2 0 0 2 2 2 0 Dec-1 protein, C terminal region DUF2536 PF10750.9 RLN50743.1 - 0.15 12.0 0.2 24 4.9 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) eIF3_N PF09440.10 RLN50743.1 - 0.89 10.0 4.3 0.96 9.9 2.3 2.1 3 0 0 3 3 3 0 eIF3 subunit 6 N terminal domain Oxidored_q6 PF01058.22 RLN50744.1 - 2.1e-21 76.1 0.0 4.4e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Replic_Relax PF13814.6 RLN50761.1 - 0.16 12.0 0.1 0.3 11.1 0.1 1.4 1 0 0 1 1 1 0 Replication-relaxation CDC14 PF08045.11 RLN50761.1 - 0.19 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Cell division control protein 14, SIN component FYVE PF01363.21 RLN50762.1 - 1.9e-10 40.7 6.7 1.9e-10 40.7 6.7 1.8 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 RLN50762.1 - 0.013 15.7 7.5 0.014 15.6 4.9 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger C1_1 PF00130.22 RLN50762.1 - 1.3 9.0 8.3 0.085 12.8 2.3 2.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MASE1 PF05231.14 RLN50763.1 - 0.035 13.2 0.1 0.043 13.0 0.1 1.0 1 0 0 1 1 1 0 MASE1 Glyco_transf_20 PF00982.21 RLN50765.1 - 1.2e-150 502.3 0.0 1.6e-98 330.5 0.0 3.1 3 0 0 3 3 3 3 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 RLN50765.1 - 1.1e-42 145.8 0.0 5.1e-42 143.6 0.0 2.0 1 1 0 1 1 1 1 Trehalose-phosphatase Lipase_GDSL PF00657.22 RLN50765.1 - 0.041 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase FlxA PF14282.6 RLN50765.1 - 4.1 7.5 7.9 0.22 11.5 2.0 1.9 2 0 0 2 2 2 0 FlxA-like protein Rad10 PF03834.14 RLN50766.1 - 1.1e-37 128.6 0.0 1.9e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 RLN50766.1 - 5.4e-06 26.9 0.0 9.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 RLN50766.1 - 2.1e-05 24.2 0.0 4.5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.7 RLN50766.1 - 7.1e-05 22.8 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif Aldedh PF00171.22 RLN50771.1 - 7.8e-169 562.0 0.1 8.9e-169 561.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family EFG_IV PF03764.18 RLN50772.1 - 1.3e-29 102.4 0.0 6.8e-29 100.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 RLN50772.1 - 4.3e-20 71.5 0.0 8.2e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 RLN50772.1 - 7.1e-14 51.7 0.0 1.4e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 RLN50772.1 - 1.9e-11 44.2 0.0 3.9e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DDE_1 PF03184.19 RLN50774.1 - 3.1e-25 88.8 0.0 3.8e-16 59.2 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN50774.1 - 2.2e-14 53.2 0.0 5.9e-13 48.6 0.0 2.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 RLN50774.1 - 1.5e-05 24.6 0.8 3.4e-05 23.5 0.8 1.6 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain zf-CCHC PF00098.23 RLN50778.1 - 9.9e-06 25.4 1.7 1.5e-05 24.8 1.7 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 RLN50778.1 - 4e-05 23.8 0.1 8.6e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein TFIIA PF03153.13 RLN50778.1 - 4.3 7.2 20.0 8.2 6.3 20.1 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ORC2 PF04084.14 RLN50780.1 - 0.11 11.4 0.1 0.21 10.4 0.1 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 2 Complex1_LYR PF05347.15 RLN50781.1 - 4e-13 49.2 1.1 5.7e-13 48.7 1.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 RLN50781.1 - 7.1e-05 23.5 0.1 8.8e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 RLN50781.1 - 0.0029 18.2 0.1 0.0037 17.8 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like SKA2 PF16740.5 RLN50781.1 - 0.021 14.6 0.2 0.037 13.8 0.2 1.4 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 WLM PF08325.10 RLN50783.1 - 1.2e-43 149.4 1.3 1.5e-43 149.1 0.1 1.7 2 1 0 2 2 2 1 WLM domain DUF45 PF01863.17 RLN50783.1 - 0.0016 18.5 1.4 0.0038 17.3 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF45 SVIP PF15811.5 RLN50783.1 - 0.0045 17.4 1.2 0.0045 17.4 1.2 2.9 2 1 1 3 3 3 1 Small VCP/p97-interacting protein DUF1281 PF06924.11 RLN50783.1 - 0.094 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) VPS11_C PF12451.8 RLN50784.1 - 7.5e-15 54.9 0.2 1.1e-14 54.3 0.2 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal DUF2527 PF10736.9 RLN50784.1 - 0.052 13.4 0.2 0.069 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) DUF4570 PF15134.6 RLN50789.1 - 0.13 12.3 0.9 0.4 10.7 0.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) malic PF00390.19 RLN50790.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Malic enzyme, N-terminal domain HD PF01966.22 RLN50793.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 HD domain HIT PF01230.23 RLN50794.1 - 2.4e-26 92.3 0.0 3.1e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 RLN50794.1 - 1.4e-18 67.5 0.0 1.8e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CLU_N PF15044.6 RLN50795.1 - 8.6e-14 51.7 0.7 4.1e-13 49.5 0.0 2.4 2 1 0 2 2 2 1 Mitochondrial function, CLU-N-term Presenilin PF01080.17 RLN50795.1 - 0.55 8.9 4.9 0.82 8.4 4.9 1.2 1 0 0 1 1 1 0 Presenilin Herpes_UL25 PF01499.16 RLN50795.1 - 2.3 6.6 7.4 3.4 6.1 7.4 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family TMEM214 PF10151.9 RLN50795.1 - 5.1 5.4 10.9 6.9 5.0 10.9 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator RP-C_C PF11800.8 RLN50795.1 - 9.1 6.3 9.4 4.4 7.3 5.8 2.0 2 0 0 2 2 2 0 Replication protein C C-terminal region KAP PF05804.12 RLN50796.1 - 1.9e-31 109.0 0.2 2.1e-31 108.9 0.2 1.0 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Peptidase_M3_N PF08439.10 RLN50796.1 - 0.68 10.2 4.6 3.2 8.1 0.7 2.8 3 0 0 3 3 3 0 Oligopeptidase F KAP PF05804.12 RLN50797.1 - 9e-95 318.3 0.2 1.1e-94 318.0 0.2 1.0 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm PF00514.23 RLN50797.1 - 4.5e-06 26.5 0.1 0.058 13.5 0.0 4.2 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.14 RLN50797.1 - 0.014 14.7 0.1 1.3 8.3 0.1 2.7 2 0 0 2 2 2 0 V-ATPase subunit H RICTOR_M PF14666.6 RLN50797.1 - 0.097 12.5 0.1 0.43 10.4 0.0 2.1 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain TFIIS_M PF07500.14 RLN50798.1 - 6e-15 55.7 0.1 2.2e-14 53.9 0.1 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain Mannosyl_trans3 PF11051.8 RLN50825.1 - 0.00067 19.1 0.1 0.00067 19.1 0.1 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative Radial_spoke_3 PF06098.11 RLN50844.1 - 9.7e-101 336.8 7.8 1.2e-100 336.5 7.8 1.1 1 0 0 1 1 1 1 Radial spoke protein 3 DUF444 PF04285.12 RLN50844.1 - 0.008 15.3 1.5 0.008 15.3 1.5 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF444) DUF4407 PF14362.6 RLN50844.1 - 6.6 6.0 10.3 2.4 7.4 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AAA PF00004.29 RLN50845.1 - 1.3e-16 61.2 0.0 1.9e-08 34.8 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RLN50845.1 - 0.00013 22.0 0.0 0.00036 20.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RLN50845.1 - 0.00034 21.0 0.0 0.00074 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 RLN50845.1 - 0.0021 18.6 0.0 0.0054 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 RLN50845.1 - 0.0061 15.8 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 RLN50845.1 - 0.0073 16.6 0.0 0.02 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RLN50845.1 - 0.024 15.0 0.1 0.063 13.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 RLN50845.1 - 0.028 14.8 0.0 0.095 13.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase RuvB_N PF05496.12 RLN50845.1 - 0.029 14.1 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 RLN50845.1 - 0.035 13.8 0.1 0.072 12.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RLN50845.1 - 0.042 13.4 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 RLN50845.1 - 0.056 13.6 0.0 0.17 12.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 RLN50845.1 - 0.057 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RLN50845.1 - 0.06 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 RLN50845.1 - 0.07 12.9 1.0 0.11 12.3 0.1 1.7 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 RLN50845.1 - 0.17 11.8 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain Sugar_tr PF00083.24 RLN50848.1 - 5.9e-33 114.4 9.3 7.6e-33 114.0 9.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN50848.1 - 6.5e-15 54.9 15.1 7.9e-15 54.6 15.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 RLN50848.1 - 0.0061 15.0 3.3 0.0079 14.7 3.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4229 PF14012.6 RLN50848.1 - 6.6 6.9 9.6 0.78 9.9 3.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Fascin PF06268.13 RLN50849.1 - 0.025 14.8 0.1 0.17 12.1 0.1 1.9 1 1 1 2 2 2 0 Fascin domain PP2C PF00481.21 RLN50856.1 - 6.2e-37 127.6 0.0 8.7e-34 117.3 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.25 RLN50856.1 - 1.5e-28 99.9 0.0 8.1e-28 97.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN50856.1 - 2.2e-08 33.7 0.0 7.7e-08 31.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase SpoIIE PF07228.12 RLN50856.1 - 0.00016 21.6 0.0 0.043 13.7 0.1 3.0 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) Kinase-like PF14531.6 RLN50856.1 - 0.011 15.1 0.0 3.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 RLN50856.1 - 0.022 14.1 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PP2C_2 PF13672.6 RLN50856.1 - 0.051 13.2 2.2 1.3 8.6 3.7 2.5 2 1 0 2 2 2 0 Protein phosphatase 2C zf-C2H2_4 PF13894.6 RLN50856.1 - 0.085 13.7 5.9 0.44 11.5 3.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 RLN50856.1 - 3.1 8.4 5.6 10 6.8 2.8 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Taxilin PF09728.9 RLN50868.1 - 7.1e-54 183.1 39.3 1.1e-53 182.5 39.3 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF4201 PF13870.6 RLN50868.1 - 0.00089 19.0 10.2 0.00089 19.0 10.2 3.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) ERM PF00769.19 RLN50868.1 - 0.013 15.3 16.6 0.013 15.3 16.6 2.9 2 1 1 3 3 3 0 Ezrin/radixin/moesin family Cadherin_2 PF08266.12 RLN50868.1 - 0.067 13.0 1.4 0.19 11.6 0.2 2.5 2 0 0 2 2 2 0 Cadherin-like XhlA PF10779.9 RLN50868.1 - 2 8.7 9.0 28 5.0 0.0 4.1 3 1 0 3 3 3 0 Haemolysin XhlA MIS13 PF08202.11 RLN50868.1 - 2.4 7.4 23.6 0.023 14.0 8.2 2.4 1 1 1 2 2 2 0 Mis12-Mtw1 protein family Spc42p PF11544.8 RLN50868.1 - 9 6.4 19.5 0.073 13.1 1.1 4.2 2 1 3 5 5 5 0 Spindle pole body component Spc42p zf-rbx1 PF12678.7 RLN50869.1 - 2.9e-20 72.3 7.0 3.4e-20 72.1 7.0 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 RLN50869.1 - 6.4e-11 42.2 3.1 7.3e-11 42.0 3.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 RLN50869.1 - 2.5e-08 34.1 6.0 3.5e-08 33.7 6.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN50869.1 - 0.00012 21.8 8.3 0.00044 20.0 8.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN50869.1 - 0.00041 20.2 8.7 0.0029 17.4 8.7 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN50869.1 - 0.016 15.0 7.8 0.026 14.3 7.8 1.6 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 RLN50869.1 - 0.031 14.1 5.5 0.1 12.5 5.5 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 RLN50869.1 - 0.041 14.0 4.8 0.052 13.7 4.8 1.2 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 RLN50869.1 - 0.045 13.8 3.3 0.045 13.8 3.3 1.6 1 1 1 2 2 2 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 RLN50869.1 - 0.063 12.9 9.2 0.16 11.6 9.2 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type SCIFF PF13165.6 RLN50869.1 - 0.11 12.4 3.7 0.18 11.7 3.7 1.3 1 0 0 1 1 1 0 Six-cysteine peptide SCIFF zf-C3HC4_4 PF15227.6 RLN50869.1 - 0.23 11.7 0.7 0.23 11.7 0.7 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 RLN50869.1 - 0.48 10.4 7.6 3.4 7.7 7.6 1.9 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING-like PF08746.11 RLN50869.1 - 3 8.2 9.9 22 5.5 9.9 2.1 1 1 0 1 1 1 0 RING-like domain GYF PF02213.16 RLN50870.1 - 1.6e-16 59.7 0.3 2.9e-16 58.8 0.3 1.5 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 RLN50870.1 - 0.00032 20.4 0.8 0.0011 18.7 0.1 2.4 2 0 0 2 2 2 1 GYF domain 2 Ras PF00071.22 RLN50871.1 - 5.3e-13 48.9 0.0 8.9e-08 31.9 0.0 2.3 1 1 1 2 2 2 2 Ras family Roc PF08477.13 RLN50871.1 - 8.5e-05 22.8 0.0 0.00093 19.4 0.0 2.3 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 RLN50871.1 - 0.043 13.9 0.0 0.082 13.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DLIC PF05783.11 RLN50871.1 - 0.11 11.3 0.0 0.27 10.0 0.0 1.5 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Zip PF02535.22 RLN50872.1 - 8.1e-40 137.0 11.9 9.3e-40 136.9 11.9 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Ax_dynein_light PF10211.9 RLN50874.1 - 2e-66 223.5 0.8 2.2e-66 223.4 0.8 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain Pedibin PF08182.11 RLN50874.1 - 0.1 12.4 0.8 0.1 12.4 0.8 2.7 3 0 0 3 3 3 0 Pedibin/Hym-346 family DivIC PF04977.15 RLN50874.1 - 0.32 10.8 4.2 0.52 10.1 3.3 1.8 1 1 0 1 1 1 0 Septum formation initiator DUF4520 PF15016.6 RLN50875.1 - 0.011 15.8 0.1 0.027 14.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) CemA PF03040.14 RLN50875.1 - 0.24 11.3 2.1 0.42 10.5 0.2 2.0 1 1 1 2 2 2 0 CemA family UBA PF00627.31 RLN50909.1 - 0.0011 18.9 0.1 0.0024 17.8 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Pro_CA PF00484.19 RLN50910.1 - 1.5e-48 165.0 0.1 2.8e-48 164.2 0.1 1.4 1 0 0 1 1 1 1 Carbonic anhydrase Pro_CA PF00484.19 RLN50911.1 - 3.9e-21 76.0 0.1 9.6e-21 74.7 0.0 1.6 2 0 0 2 2 2 1 Carbonic anhydrase DUF812 PF05667.11 RLN50912.1 - 0.00036 19.6 9.5 0.0006 18.8 9.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Matrilin_ccoil PF10393.9 RLN50912.1 - 0.0048 16.7 2.9 0.76 9.7 0.3 2.9 2 0 0 2 2 2 2 Trimeric coiled-coil oligomerisation domain of matrilin MobB PF03205.14 RLN50912.1 - 0.029 14.2 0.1 0.061 13.2 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF3287 PF11690.8 RLN50912.1 - 0.57 9.9 6.5 0.87 9.3 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) Uso1_p115_C PF04871.13 RLN50912.1 - 0.67 10.3 12.9 0.12 12.7 6.0 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region CCDC53 PF10152.9 RLN50912.1 - 0.84 10.0 5.2 2.7 8.4 5.2 1.8 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex TMPIT PF07851.13 RLN50912.1 - 1.3 8.2 4.7 0.43 9.8 1.1 1.8 2 0 0 2 2 2 0 TMPIT-like protein ADIP PF11559.8 RLN50912.1 - 3.1 7.9 15.3 0.1 12.7 6.9 2.4 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding ABC_tran_CTD PF16326.5 RLN50912.1 - 9.2 6.6 12.7 14 6.0 7.0 2.9 1 1 2 3 3 3 0 ABC transporter C-terminal domain Pro_CA PF00484.19 RLN50913.1 - 1.1e-47 162.3 0.2 1.7e-47 161.6 0.2 1.3 1 0 0 1 1 1 1 Carbonic anhydrase Oxidored_molyb PF00174.19 RLN50921.1 - 1.4e-54 184.3 0.0 2.2e-54 183.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 RLN50921.1 - 1e-51 174.6 1.0 1.7e-51 173.9 1.0 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 RLN50921.1 - 4.9e-33 113.4 0.0 1.1e-32 112.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 RLN50921.1 - 1.1e-30 106.4 0.0 3.6e-30 104.8 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 RLN50921.1 - 2.7e-22 78.7 0.0 5.6e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 RLN50921.1 - 0.00044 20.4 0.0 0.0018 18.4 0.0 1.9 1 1 1 2 2 2 1 Ferric reductase NAD binding domain DUF3638 PF12340.8 RLN50923.1 - 1.6e-60 204.2 0.3 3.6e-60 203.1 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 RLN50923.1 - 1.1e-15 56.7 0.0 2.1e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Aldo_ket_red PF00248.21 RLN50927.1 - 1.9e-24 86.4 0.0 2.1e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-RanBP PF00641.18 RLN50932.1 - 5.9e-05 22.3 6.7 0.0001 21.5 6.7 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others UPF0270 PF06794.12 RLN50933.1 - 0.55 10.3 2.9 0.47 10.6 0.7 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) LRR_4 PF12799.7 RLN50934.1 - 1.7e-09 37.8 0.2 0.00036 20.9 0.2 2.7 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN50934.1 - 3.4e-09 36.3 3.9 4.3e-05 23.2 0.7 3.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 RLN50934.1 - 1.4e-05 25.0 0.9 1.5 9.6 0.0 4.5 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 RLN50934.1 - 0.17 12.0 1.5 0.68 10.1 0.0 2.7 4 0 0 4 4 4 0 Leucine Rich repeat GreA_GreB_N PF03449.15 RLN50935.1 - 0.0064 16.6 0.6 0.0072 16.4 0.6 1.3 1 1 0 1 1 1 1 Transcription elongation factor, N-terminal HeH PF12949.7 RLN50935.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 HeH/LEM domain fn3 PF00041.21 RLN50937.1 - 1.5e-07 31.7 0.1 3.1e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain TIG PF01833.24 RLN50937.1 - 0.0011 19.0 0.0 0.0038 17.3 0.0 1.9 1 0 0 1 1 1 1 IPT/TIG domain Abhydrolase_6 PF12697.7 RLN50938.1 - 1.8e-14 54.9 4.2 2.5e-14 54.4 4.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN50938.1 - 4e-10 39.4 0.0 5.3e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN50938.1 - 1.6e-08 34.5 0.1 5.9e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 RLN50938.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) VirJ PF06057.11 RLN50938.1 - 0.06 13.2 0.0 0.65 9.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) Pkinase_Tyr PF07714.17 RLN50939.1 - 3.3e-97 324.8 0.0 5.3e-41 140.6 0.0 7.0 6 2 0 6 6 6 4 Protein tyrosine kinase Pkinase PF00069.25 RLN50939.1 - 1.1e-84 283.9 0.0 5.7e-38 130.8 0.0 6.3 4 2 1 5 5 5 4 Protein kinase domain Kinase-like PF14531.6 RLN50939.1 - 9.6e-06 25.1 0.0 0.11 11.8 0.0 3.6 4 0 0 4 4 4 2 Kinase-like RIO1 PF01163.22 RLN50939.1 - 0.025 14.2 0.0 1 8.9 0.0 2.6 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 RLN50939.1 - 0.062 12.6 0.1 2 7.7 0.0 3.0 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 RLN50939.1 - 0.098 11.7 0.9 0.88 8.6 0.1 2.2 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.23 RLN50939.1 - 0.55 10.1 12.7 0.26 11.2 0.1 4.4 5 0 0 5 5 5 0 Phosphotransferase enzyme family Urocanase_C PF17392.2 RLN50940.1 - 5.3e-87 290.3 2.1 8.4e-87 289.7 2.1 1.3 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase PF01175.18 RLN50940.1 - 2e-70 236.7 0.0 3.6e-70 235.9 0.0 1.4 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Sugar_tr PF00083.24 RLN50950.1 - 7.9e-19 67.8 7.8 8.7e-19 67.7 7.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN50950.1 - 0.0012 17.9 13.6 0.0014 17.6 13.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2545 PF10810.8 RLN50950.1 - 0.5 10.5 5.6 3.6 7.8 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2545) DUF2070 PF09843.9 RLN50950.1 - 0.71 8.1 7.4 0.85 7.8 7.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Peptidase_U4 PF03419.13 RLN50950.1 - 2 7.6 6.1 2.4 7.4 6.1 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA tRNA-synt_1d PF00750.19 RLN50956.1 - 7e-62 209.4 0.0 9.6e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 RLN50956.1 - 3.5e-27 95.0 0.2 2.8e-26 92.1 0.0 2.5 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 RLN50956.1 - 4e-06 27.3 0.0 5.2e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1 PF00133.22 RLN50956.1 - 0.0013 17.0 0.0 0.023 12.9 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 RLN50956.1 - 0.028 13.8 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain PHD PF00628.29 RLN50957.1 - 0.37 10.7 36.3 0.022 14.7 4.2 5.0 5 1 0 5 5 5 0 PHD-finger Sugar_tr PF00083.24 RLN50958.1 - 8.8e-52 176.5 0.4 1.2e-51 176.0 0.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN50958.1 - 1.9e-10 40.2 7.5 1.9e-10 40.2 7.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily ADH_N PF08240.12 RLN50960.1 - 9.6e-33 112.3 0.5 2.2e-32 111.2 0.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN50960.1 - 7.5e-26 90.6 0.5 1.3e-25 89.8 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 RLN50960.1 - 1.1e-08 34.9 0.1 2e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 RLN50960.1 - 3.8e-07 31.2 0.0 7.4e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 RLN50960.1 - 0.0028 17.0 1.0 0.0041 16.5 1.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 RLN50960.1 - 0.13 13.0 0.1 0.29 11.9 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain MULE PF10551.9 RLN50961.1 - 4.5e-08 33.4 2.3 8.6e-06 26.1 2.3 2.8 1 1 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 RLN50961.1 - 0.01 15.6 0.1 0.01 15.6 0.1 2.6 3 0 0 3 3 3 0 Transposase ERAP1_C PF11838.8 RLN50961.1 - 0.11 12.0 0.1 0.89 9.0 0.1 2.4 2 0 0 2 2 2 0 ERAP1-like C-terminal domain HTH_micro PF17007.5 RLN50961.1 - 1.9 7.2 4.6 5.7 5.6 0.1 2.1 2 0 0 2 2 2 0 HTH-like DUF2254 PF10011.9 RLN50962.1 - 0.6 8.9 3.8 0.75 8.6 2.6 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2254) DUF2013 PF09431.10 RLN50963.1 - 2.2e-11 44.1 0.2 3.5e-11 43.4 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) ISN1 PF06437.11 RLN50975.1 - 8.4e-66 222.5 0.0 1.1e-65 222.2 0.0 1.1 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Rtf2 PF04641.12 RLN50975.1 - 0.00036 20.0 5.6 0.00052 19.5 5.6 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger Sec62 PF03839.16 RLN50975.1 - 1.3 8.5 4.4 1.8 8.0 4.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 adh_short_C2 PF13561.6 RLN50976.1 - 2.2e-44 151.7 0.1 4.3e-44 150.8 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RLN50976.1 - 1.3e-34 119.4 0.9 1.3e-34 119.4 0.9 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 RLN50976.1 - 3.9e-08 33.4 0.5 1.2e-07 31.9 0.5 1.8 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 RLN50976.1 - 0.11 11.5 0.2 0.21 10.5 0.2 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3683 PF12447.8 RLN50976.1 - 0.34 11.0 0.1 0.34 11.0 0.1 3.4 2 2 0 2 2 2 0 Protein of unknown function (DUF3683) PRR22 PF15776.5 RLN50976.1 - 0.87 8.9 2.9 1.4 8.2 2.9 1.3 1 0 0 1 1 1 0 Proline-rich protein family 22 NmrA PF05368.13 RLN50976.1 - 1.7 8.1 6.2 0.67 9.5 0.5 2.9 3 0 0 3 3 3 0 NmrA-like family RabGAP-TBC PF00566.18 RLN50977.1 - 6.3e-38 130.6 0.0 9.4e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_5 PF13857.6 RLN50977.1 - 9e-22 76.9 2.0 0.00027 21.2 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN50977.1 - 6.7e-21 74.4 4.1 8.5e-06 26.2 0.2 4.8 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN50977.1 - 2.6e-20 72.8 3.2 1.4e-08 35.2 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN50977.1 - 3.7e-18 63.7 3.7 0.00067 19.9 0.1 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 RLN50977.1 - 2e-11 43.8 5.7 0.032 14.7 0.2 4.9 5 0 0 5 5 5 3 Ankyrin repeat B12D PF06522.11 RLN50978.1 - 9.2e-12 44.6 0.0 1.5e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit B12D PF06522.11 RLN50979.1 - 3.7e-09 36.2 0.0 5.2e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit B12D PF06522.11 RLN50980.1 - 3.7e-09 36.2 0.0 5.2e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit BT1 PF03092.16 RLN50981.1 - 2.9e-17 62.1 9.9 1e-11 43.8 0.1 3.2 3 0 0 3 3 3 3 BT1 family B12D PF06522.11 RLN50982.1 - 2.2e-19 69.0 0.1 2.8e-08 33.4 0.0 2.3 2 0 0 2 2 2 2 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF2749 PF10907.8 RLN50982.1 - 0.008 16.3 0.0 6.7 7.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2749) Rubella_Capsid PF05750.11 RLN50982.1 - 0.011 15.3 0.0 5.1 6.6 0.0 2.0 1 1 0 2 2 2 0 Rubella capsid protein DUF2374 PF09574.10 RLN50982.1 - 0.045 13.6 0.9 9.5 6.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) DUF2502 PF10697.9 RLN50982.1 - 0.057 13.8 5.9 1.8 9.0 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2502) DIRP PF06584.13 RLN50982.1 - 0.46 10.7 3.8 11 6.3 0.3 2.2 2 0 0 2 2 2 0 DIRP DHC_N1 PF08385.12 RLN50987.1 - 3.8e-165 550.7 0.4 3.8e-165 550.7 0.4 4.5 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 RLN50987.1 - 4.6e-124 414.5 9.0 4.6e-124 414.5 9.0 3.8 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Importin_rep_6 PF18829.1 RLN50987.1 - 0.11 12.7 0.6 3.7 7.7 0.0 3.6 3 0 0 3 3 3 0 Importin repeat 6 MSA-2c PF12238.8 RLN50987.1 - 0.2 11.6 10.9 0.22 11.5 0.3 3.2 1 1 1 2 2 2 0 Merozoite surface antigen 2c DUF2786 PF10979.8 RLN50987.1 - 3.1 7.8 5.6 14 5.7 1.8 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) TPR_16 PF13432.6 RLN50991.1 - 1.2e-06 29.0 0.1 1.2e-06 29.0 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 RLN50991.1 - 6.5e-06 25.9 5.5 0.01 15.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN50991.1 - 1.5e-05 25.4 0.0 1.5e-05 25.4 0.0 2.8 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN50991.1 - 6.3e-05 22.6 0.1 0.0055 16.4 0.0 3.0 2 1 1 3 3 3 1 TPR repeat TPR_14 PF13428.6 RLN50991.1 - 0.0001 22.8 11.8 0.00016 22.2 0.0 5.1 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN50991.1 - 0.00012 22.2 0.1 0.00054 20.1 0.1 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN50991.1 - 0.00016 21.8 0.1 0.0013 18.9 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN50991.1 - 0.0002 21.1 0.3 0.69 9.8 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN50991.1 - 0.00046 20.6 0.1 0.00046 20.6 0.1 3.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN50991.1 - 0.002 18.4 3.3 0.036 14.3 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN50991.1 - 0.0022 17.8 2.7 0.085 12.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN50991.1 - 0.01 15.8 1.1 19 5.6 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 RLN50991.1 - 0.013 15.8 0.1 0.27 11.6 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 RLN50991.1 - 0.017 15.7 1.0 0.063 13.9 0.0 2.6 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 RLN50991.1 - 0.023 14.9 0.0 7.5 7.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Comm PF15957.5 RLN50991.1 - 0.15 12.4 0.1 0.69 10.3 0.1 2.0 2 0 0 2 2 2 0 Commissureless Ribosomal_L44 PF00935.19 RLN50993.1 - 3.1e-26 91.6 9.8 4.8e-26 91.0 9.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 CCT PF06203.14 RLN50997.1 - 4.5e-11 42.6 7.1 7.5e-11 41.9 7.1 1.4 1 0 0 1 1 1 1 CCT motif FATC PF02260.20 RLN50997.1 - 0.012 15.4 0.0 16 5.4 0.0 3.4 3 0 0 3 3 3 0 FATC domain DUF285 PF03382.14 RLN50997.1 - 0.029 14.1 1.1 0.31 10.8 1.1 2.5 1 1 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 RCC1 PF00415.18 RLN50999.1 - 6.7e-39 132.3 5.3 1.1e-15 58.0 0.3 4.2 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN50999.1 - 4.5e-16 58.2 21.4 6e-08 32.3 0.0 4.6 5 1 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 RLN50999.1 - 3.9e-06 27.1 0.0 9.7e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain 2-oxoacid_dh PF00198.23 RLN51000.1 - 8e-53 179.3 0.2 1.1e-41 142.8 0.0 2.0 2 0 0 2 2 2 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Sybindin PF04099.12 RLN51006.1 - 5.3e-29 101.0 0.0 6.6e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 RLN51006.1 - 0.00027 21.0 0.0 0.00043 20.4 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Trypsin_2 PF13365.6 RLN51007.1 - 5.4e-21 76.1 0.1 9.3e-21 75.3 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 RLN51007.1 - 1.2e-14 54.4 0.5 2.5e-14 53.3 0.1 1.7 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.26 RLN51007.1 - 3.9e-12 46.5 0.0 5.4e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 RLN51007.1 - 1.3e-11 44.1 0.1 3.5e-11 42.8 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RLN51007.1 - 7e-07 29.5 0.1 2.2e-06 27.9 0.1 1.8 1 0 0 1 1 1 1 PDZ domain Peptidase_S7 PF00949.21 RLN51007.1 - 0.0036 17.1 0.9 0.0068 16.2 0.9 1.4 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.9 RLN51007.1 - 0.023 13.4 0.5 0.029 13.0 0.5 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF31 PF01732.16 RLN51007.1 - 0.055 13.0 0.1 0.065 12.8 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) TPR_2 PF07719.17 RLN51008.1 - 3e-27 92.5 0.0 0.076 13.2 0.0 11.2 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.6 RLN51008.1 - 1e-24 86.8 3.1 6.3e-09 36.3 0.0 6.7 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 RLN51008.1 - 6.4e-20 71.4 0.0 0.00016 22.1 0.0 5.7 2 1 3 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 RLN51008.1 - 3.2e-19 68.3 0.0 0.0011 18.6 0.0 6.7 7 0 0 7 7 7 3 TPR repeat TPR_14 PF13428.6 RLN51008.1 - 1.2e-18 66.1 4.1 0.042 14.7 0.0 10.1 4 1 6 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN51008.1 - 1.9e-18 65.1 0.0 0.028 14.6 0.0 9.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN51008.1 - 3.3e-17 61.5 0.0 0.06 13.2 0.0 8.2 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 RLN51008.1 - 1e-16 60.9 11.5 0.0012 19.1 0.0 6.9 2 1 4 6 6 6 5 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN51008.1 - 7.9e-13 48.4 0.7 0.004 17.4 0.0 5.2 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 RLN51008.1 - 7e-11 41.7 0.0 0.4 11.2 0.0 7.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN51008.1 - 7.1e-09 35.1 0.5 2.5 8.3 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN51008.1 - 7.3e-09 35.7 4.8 0.0031 17.6 0.0 5.1 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 RLN51008.1 - 1.5e-08 34.7 0.2 8.3 7.3 0.0 7.8 9 0 0 9 9 8 0 Tetratricopeptide repeat Rhodanese PF00581.20 RLN51008.1 - 5.3e-05 23.7 0.0 0.00017 22.0 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain TPR_10 PF13374.6 RLN51008.1 - 0.00011 21.9 2.6 4.7 7.2 0.0 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat NARP1 PF12569.8 RLN51008.1 - 0.00016 20.7 3.9 0.0013 17.8 0.0 3.4 3 1 0 4 4 4 1 NMDA receptor-regulated protein 1 DUF3808 PF10300.9 RLN51008.1 - 0.00092 18.1 0.6 0.37 9.5 0.0 3.4 2 1 1 4 4 4 1 Protein of unknown function (DUF3808) HrpB1_HrpK PF09613.10 RLN51008.1 - 0.00099 18.7 0.0 1 9.0 0.0 2.8 1 1 1 2 2 2 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_20 PF14561.6 RLN51008.1 - 0.0023 18.2 13.5 0.27 11.6 0.0 6.2 6 1 1 7 7 6 1 Tetratricopeptide repeat DUF4810 PF16068.5 RLN51008.1 - 0.0076 16.8 2.5 0.023 15.2 0.1 3.2 2 1 0 2 2 1 1 Domain of unknown function (DUF4810) Sec16_C PF12931.7 RLN51008.1 - 0.034 13.8 0.1 0.071 12.8 0.1 1.4 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 Tryp_alpha_amyl PF00234.22 RLN51008.1 - 0.035 14.5 2.6 0.081 13.4 0.8 2.5 2 0 0 2 2 2 0 Protease inhibitor/seed storage/LTP family TPR_4 PF07721.14 RLN51008.1 - 0.042 14.5 0.3 0.042 14.5 0.3 5.9 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF2514 PF10721.9 RLN51008.1 - 1.2 9.2 6.5 0.34 10.9 0.7 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF2514) TspO_MBR PF03073.15 RLN51009.1 - 0.023 14.8 31.2 0.024 14.7 16.6 2.8 1 1 1 2 2 2 0 TspO/MBR family Cir_N PF10197.9 RLN51010.1 - 1.5e-10 41.1 6.7 1.5e-10 41.1 6.7 2.2 2 1 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR zf-CCHC_6 PF15288.6 RLN51010.1 - 0.039 13.8 0.3 0.09 12.6 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF2198 PF09964.9 RLN51011.1 - 0.013 15.5 0.2 0.013 15.5 0.2 2.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2198) CarS-like PF01864.17 RLN51011.1 - 0.042 13.8 2.4 0.052 13.5 2.4 1.1 1 0 0 1 1 1 0 CDP-archaeol synthase WD40 PF00400.32 RLN51012.1 - 6.9e-08 33.0 0.1 0.00017 22.3 0.0 4.4 4 1 0 4 4 4 1 WD domain, G-beta repeat RasGAP PF00616.19 RLN51030.1 - 9.2e-13 48.4 0.0 9e-12 45.1 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase zf_CCCH_4 PF18345.1 RLN51031.1 - 0.0002 21.3 4.8 0.00046 20.1 4.8 1.7 1 0 0 1 1 1 1 Zinc finger domain Methyltransf_32 PF13679.6 RLN51031.1 - 0.00088 19.3 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain tRNA_anti-codon PF01336.25 RLN51031.1 - 0.0055 16.7 0.2 0.015 15.3 0.2 1.7 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain zf-CCCH PF00642.24 RLN51031.1 - 0.0062 16.4 2.8 0.014 15.3 2.8 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 RLN51031.1 - 0.096 12.5 5.0 1.8 8.4 2.2 2.4 2 0 0 2 2 2 0 CCCH-type zinc finger GST_N_2 PF13409.6 RLN51037.1 - 2.6e-06 27.6 0.0 6.7e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN51037.1 - 3.7e-06 26.9 0.0 7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RLN51037.1 - 4.7e-06 26.7 0.0 1.2e-05 25.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RLN51037.1 - 0.00036 20.7 0.0 0.00071 19.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 RLN51037.1 - 0.019 14.8 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RLN51038.1 - 9.2e-14 51.5 0.0 2.2e-13 50.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN51038.1 - 5.6e-08 32.7 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RLN51038.1 - 0.00019 21.6 0.0 0.00043 20.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RLN51038.1 - 0.00035 20.9 0.0 0.046 14.1 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RLN51038.1 - 0.00066 19.8 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 RLN51038.1 - 0.099 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ADH_N PF08240.12 RLN51044.1 - 5.5e-10 39.1 0.0 6.8e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ig_C17orf99 PF17736.1 RLN51044.1 - 0.096 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 C17orf99 Ig domain Glyco_hydro_6 PF01341.17 RLN51045.1 - 1e-49 169.9 2.4 1.3e-49 169.6 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Glyco_hydro_6 PF01341.17 RLN51046.1 - 1.1e-52 179.7 0.5 1.9e-52 178.9 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 ADH_zinc_N_2 PF13602.6 RLN51046.1 - 1.2e-19 71.6 0.0 2.9e-19 70.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 RLN51046.1 - 3.2e-14 53.0 0.1 1.7e-13 50.7 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN51046.1 - 4e-06 26.7 0.0 1.8e-05 24.6 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glyco_hydro_6 PF01341.17 RLN51047.1 - 7.1e-52 177.0 0.7 1e-51 176.5 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Med3 PF11593.8 RLN51047.1 - 0.16 11.1 11.4 0.27 10.4 11.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Glyco_hydro_6 PF01341.17 RLN51048.1 - 5e-49 167.7 0.6 8.6e-49 166.9 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Glyco_hydro_6 PF01341.17 RLN51049.1 - 2.9e-49 168.5 0.2 6e-49 167.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 SOG2 PF10428.9 RLN51049.1 - 1 8.5 24.9 1.4 8.0 24.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein ADH_zinc_N_2 PF13602.6 RLN51050.1 - 2.6e-18 67.4 0.2 4.5e-18 66.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 RLN51050.1 - 7.6e-14 51.8 0.6 1.9e-12 47.3 0.1 2.4 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN51050.1 - 9.7e-08 31.9 0.1 9.7e-07 28.6 0.0 2.4 1 1 2 3 3 3 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 RLN51050.1 - 0.0034 16.7 1.7 0.0088 15.4 1.6 1.8 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_16 PF10294.9 RLN51050.1 - 0.013 15.2 0.1 0.03 14.1 0.1 1.6 1 0 0 1 1 1 0 Lysine methyltransferase Ank_2 PF12796.7 RLN51051.1 - 1.1e-21 77.3 0.4 3e-08 34.1 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN51051.1 - 6e-19 68.2 2.6 7.3e-08 32.8 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN51051.1 - 1.5e-13 50.6 3.1 0.00015 22.0 0.0 5.3 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN51051.1 - 3.5e-10 39.2 0.2 1.1 10.1 0.0 5.8 5 1 1 6 6 6 2 Ankyrin repeat DUF5049 PF16468.5 RLN51051.1 - 0.017 15.0 0.0 37 4.3 0.0 3.9 2 1 3 5 5 5 0 Domain of unknown function (DUF5049) zf_Rg PF17915.1 RLN51051.1 - 0.13 11.6 0.0 0.46 9.9 0.0 1.8 2 0 0 2 2 2 0 Reverse gyrase zinc finger DUF1510 PF07423.11 RLN51053.1 - 0.027 14.6 0.2 0.054 13.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) RdRP_2 PF00978.21 RLN51053.1 - 0.19 10.6 0.3 0.31 9.9 0.3 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase PX PF00787.24 RLN51054.1 - 9.6e-07 28.8 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 PX domain Patatin PF01734.22 RLN51055.1 - 4.7e-14 53.0 0.3 2.1e-12 47.7 0.0 2.6 2 1 0 2 2 2 1 Patatin-like phospholipase DUF3287 PF11690.8 RLN51055.1 - 0.37 10.5 4.5 0.87 9.3 4.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) LRR_4 PF12799.7 RLN51056.1 - 9.3e-27 92.7 17.7 7e-05 23.1 0.0 11.6 9 3 4 13 13 13 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN51056.1 - 0.00047 19.8 27.9 0.093 12.5 0.1 8.0 8 3 1 9 9 9 3 Leucine rich repeat LRR_6 PF13516.6 RLN51056.1 - 0.016 15.3 6.4 1.8 8.9 0.0 6.1 6 1 1 7 7 7 0 Leucine Rich repeat LRR_9 PF14580.6 RLN51056.1 - 0.081 12.4 13.0 0.64 9.5 0.7 4.8 3 2 1 4 4 4 0 Leucine-rich repeat TFR_dimer PF04253.15 RLN51058.1 - 3.4e-31 107.8 0.0 6.1e-30 103.8 0.0 2.2 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 RLN51058.1 - 6.2e-27 94.6 0.0 3.5e-18 66.0 0.0 3.1 2 1 0 2 2 2 2 Peptidase family M28 PA PF02225.22 RLN51058.1 - 6.5e-25 87.0 0.1 1.1e-10 41.3 0.0 3.5 4 0 0 4 4 4 2 PA domain Peptidase_M20 PF01546.28 RLN51058.1 - 0.0049 16.6 0.0 0.032 13.9 0.0 1.9 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 RLN51058.1 - 0.023 14.1 0.0 0.067 12.6 0.0 1.7 2 0 0 2 2 2 0 Nicastrin LRR_6 PF13516.6 RLN51070.1 - 9.7e-06 25.2 1.6 0.3 11.2 0.0 4.5 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 RLN51070.1 - 0.0018 18.6 0.0 0.025 15.0 0.1 2.7 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN51070.1 - 0.32 11.7 1.4 1.1e+02 4.0 0.2 3.9 3 1 0 3 3 3 0 Leucine Rich Repeat HECT PF00632.25 RLN51071.1 - 9.5e-55 186.2 0.0 1.8e-54 185.3 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MIB_HERC2 PF06701.13 RLN51071.1 - 7.8e-20 70.9 9.8 2.5e-19 69.3 9.8 1.9 1 0 0 1 1 1 1 Mib_herc2 ZZ PF00569.17 RLN51071.1 - 4.4e-10 39.2 9.2 1.4e-09 37.6 9.2 1.9 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-RING_6 PF14835.6 RLN51071.1 - 0.097 12.6 0.9 0.7 9.8 0.1 2.6 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RanBP PF00641.18 RLN51071.1 - 0.12 11.7 20.4 0.01 15.1 1.2 3.3 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others DUF2054 PF10218.9 RLN51071.1 - 0.12 12.5 3.1 0.4 10.8 3.1 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2054) Glyoxalase_4 PF13669.6 RLN51071.1 - 0.14 12.4 0.0 4.8 7.5 0.0 2.6 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Vps36-NZF-N PF16988.5 RLN51071.1 - 0.53 9.7 5.4 10 5.6 0.4 2.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PSP1 PF04468.12 RLN51072.1 - 2.2e-24 85.6 2.7 3.3e-24 85.0 2.7 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region FYVE PF01363.21 RLN51073.1 - 4.2e-13 49.2 12.4 4.2e-13 49.2 12.4 2.2 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 RLN51073.1 - 0.00031 20.9 7.1 0.0014 18.9 7.1 2.2 1 0 0 1 1 1 1 FYVE-type zinc finger Atg14 PF10186.9 RLN51074.1 - 2.1e-07 30.4 7.5 6.6e-07 28.7 7.5 1.7 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 APG6 PF04111.12 RLN51074.1 - 0.00059 19.8 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Apg6 BARA domain C2 PF00168.30 RLN51074.1 - 0.014 15.6 0.0 0.031 14.6 0.0 1.5 1 0 0 1 1 1 0 C2 domain Mei5 PF10376.9 RLN51074.1 - 0.092 12.6 1.6 0.18 11.7 1.6 1.5 1 0 0 1 1 1 0 Double-strand recombination repair protein OrfB_Zn_ribbon PF07282.11 RLN51075.1 - 1.9e-15 56.5 1.8 3.5e-15 55.7 1.8 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HTH_OrfB_IS605 PF12323.8 RLN51075.1 - 6.3e-09 35.2 3.0 1.5e-08 34.0 3.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain OrfB_IS605 PF01385.19 RLN51075.1 - 0.0022 18.2 0.0 0.0083 16.3 0.0 2.0 2 0 0 2 2 2 1 Probable transposase Mu-like_Com PF10122.9 RLN51075.1 - 0.013 15.0 0.3 0.033 13.6 0.3 1.7 1 0 0 1 1 1 0 Mu-like prophage protein Com Proteasome PF00227.26 RLN51076.1 - 2.3e-36 125.1 0.7 1.6e-33 115.8 0.0 2.1 1 1 1 2 2 2 2 Proteasome subunit NAGidase PF07555.13 RLN51076.1 - 0.041 13.2 0.1 0.054 12.8 0.1 1.1 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase Polysacc_deac_1 PF01522.21 RLN51077.1 - 4.6e-11 42.7 0.0 7.7e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Kinesin PF00225.23 RLN51078.1 - 9.2e-96 320.6 0.1 9.2e-96 320.6 0.1 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RLN51078.1 - 6.5e-47 159.2 1.4 1.4e-45 154.9 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding DUF1664 PF07889.12 RLN51078.1 - 0.019 15.0 19.3 0.58 10.2 3.9 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) UPRTase PF14681.6 RLN51081.1 - 1.4e-28 99.8 0.7 4e-18 65.6 0.1 4.8 3 1 0 3 3 3 3 Uracil phosphoribosyltransferase adh_short PF00106.25 RLN51081.1 - 2.8e-20 72.6 0.1 4.1e-10 39.4 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN51081.1 - 4.8e-16 59.0 0.5 5.1e-10 39.3 0.1 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Zn-ribbon_8 PF09723.10 RLN51081.1 - 0.12 12.5 2.9 0.15 12.2 1.0 2.2 2 0 0 2 2 2 0 Zinc ribbon domain STIL_N PF15253.6 RLN51082.1 - 6.2e-18 64.9 0.0 1e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 SCL-interrupting locus protein N-terminus PI3_PI4_kinase PF00454.27 RLN51083.1 - 3.3e-19 69.7 0.0 6.3e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DP PF08781.10 RLN51084.1 - 4.3e-30 104.4 2.3 6.1e-30 103.9 0.9 1.9 2 0 0 2 2 2 1 Transcription factor DP Bromodomain PF00439.25 RLN51084.1 - 5.1e-20 71.3 0.0 1.2e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 RLN51084.1 - 4.6e-10 39.8 0.0 9.1e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RLN51084.1 - 4.4e-08 33.1 0.0 1.1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN51084.1 - 2e-05 24.9 0.2 4e-05 24.0 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN51084.1 - 0.088 12.8 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 FR47-like protein Mago_nashi PF02792.14 RLN51085.1 - 1.2e-22 80.5 0.5 1.5e-18 67.3 0.2 2.0 2 0 0 2 2 2 2 Mago nashi protein SPX PF03105.19 RLN51086.1 - 2.3e-20 73.9 4.0 1.8e-13 51.2 2.6 2.5 1 1 1 2 2 2 2 SPX domain CitMHS PF03600.16 RLN51086.1 - 1.8e-17 63.5 19.0 3.4e-17 62.6 19.0 1.5 1 1 0 1 1 1 1 Citrate transporter Na_sulph_symp PF00939.19 RLN51086.1 - 1.2e-12 47.7 21.0 1.3e-10 41.0 17.3 2.5 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region Vps52 PF04129.12 RLN51087.1 - 1.7e-123 413.1 12.5 1.5e-121 406.6 12.5 2.3 1 1 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 RLN51087.1 - 4.3e-11 42.0 15.8 3e-10 39.2 8.2 2.1 2 0 0 2 2 2 2 Exocyst complex component Sec3 Exo70 PF03081.15 RLN51087.1 - 0.012 14.7 1.7 0.017 14.2 0.2 2.1 2 1 1 3 3 3 0 Exo70 exocyst complex subunit ORMDL PF04061.14 RLN51088.1 - 1.5e-44 151.1 0.2 1.7e-44 150.9 0.2 1.0 1 0 0 1 1 1 1 ORMDL family Ripply PF14998.6 RLN51088.1 - 0.13 12.9 0.0 0.19 12.4 0.0 1.3 1 0 0 1 1 1 0 Transcription Regulator TRAPPC-Trs85 PF12739.7 RLN51089.1 - 2e-75 254.3 0.0 2.9e-75 253.8 0.0 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.11 RLN51089.1 - 0.12 9.7 0.0 0.2 8.9 0.0 1.2 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Mago_nashi PF02792.14 RLN51090.1 - 2e-35 122.0 0.0 2.5e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Mago nashi protein Ras PF00071.22 RLN51091.1 - 6.3e-31 107.2 0.2 5.1e-19 68.4 0.1 2.0 1 1 0 2 2 2 2 Ras family Roc PF08477.13 RLN51091.1 - 1e-11 45.1 0.0 1.3e-07 31.8 0.0 2.3 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 RLN51091.1 - 0.056 13.4 0.0 13 5.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Arf PF00025.21 RLN51091.1 - 0.065 12.7 0.0 0.54 9.7 0.0 1.9 1 1 1 2 2 2 0 ADP-ribosylation factor family TniB PF05621.11 RLN51091.1 - 0.18 11.2 0.0 0.52 9.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Utp12 PF04003.12 RLN51099.1 - 7.2e-15 55.2 0.5 7.2e-15 55.2 0.5 2.1 2 0 0 2 2 2 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 RLN51099.1 - 3e-09 37.0 0.0 4.9e-05 23.6 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 RLN51099.1 - 0.001 18.7 5.1 0.001 18.7 5.1 2.5 2 1 0 2 2 2 1 PQQ-like domain WD40 PF00400.32 RLN51099.1 - 0.009 16.8 0.0 4.8 8.2 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat ATP-synt_Z PF16594.5 RLN51099.1 - 0.13 11.8 0.5 0.75 9.3 0.1 2.3 2 0 0 2 2 2 0 Putative AtpZ or ATP-synthase-associated IQ PF00612.27 RLN51099.1 - 0.4 10.6 15.0 1.4 8.9 1.3 3.7 3 0 0 3 3 3 0 IQ calmodulin-binding motif FemAB PF02388.16 RLN51099.1 - 2.1 7.1 10.3 0.16 10.8 5.4 1.6 2 0 0 2 2 2 0 FemAB family DUF3915 PF13054.6 RLN51099.1 - 2.5 8.1 9.0 1.4 8.9 6.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) SHQ1 PF04925.15 RLN51100.1 - 1.8e-55 187.2 0.0 2.6e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 SHQ1 protein RRN3 PF05327.11 RLN51100.1 - 0.044 12.3 3.7 0.059 11.9 3.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AAA PF00004.29 RLN51101.1 - 2.9e-37 128.0 0.0 4.9e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 RLN51101.1 - 4.1e-07 29.9 0.5 7.9e-07 28.9 0.5 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 RLN51101.1 - 7.6e-07 29.2 0.0 2.4e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RLN51101.1 - 1.7e-06 28.2 0.0 5.3e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 RLN51101.1 - 4.2e-06 27.2 0.0 9.6e-05 22.8 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RLN51101.1 - 1.6e-05 25.2 0.4 0.0077 16.5 0.0 3.0 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 RLN51101.1 - 6e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RLN51101.1 - 0.0013 18.9 0.2 0.0035 17.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 RLN51101.1 - 0.0021 17.8 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 RLN51101.1 - 0.0027 17.0 0.0 0.0056 15.9 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activat PF00158.26 RLN51101.1 - 0.0028 17.4 0.1 0.038 13.7 0.1 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 RLN51101.1 - 0.0048 16.3 0.0 0.012 15.0 0.1 1.6 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RLN51101.1 - 0.0049 16.7 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 RLN51101.1 - 0.0054 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RLN51101.1 - 0.006 17.1 0.4 0.023 15.3 0.0 2.1 2 1 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 RLN51101.1 - 0.011 16.1 0.0 0.025 15.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase RILP PF11461.8 RLN51101.1 - 0.012 15.8 1.6 0.023 14.9 1.6 1.5 1 0 0 1 1 1 0 Rab interacting lysosomal protein DUF815 PF05673.13 RLN51101.1 - 0.013 14.7 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 RLN51101.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_13 PF13166.6 RLN51101.1 - 0.015 14.0 0.1 0.8 8.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 RLN51101.1 - 0.016 15.3 0.0 0.072 13.1 0.0 2.1 3 0 0 3 3 3 0 AAA domain Parvo_NS1 PF01057.17 RLN51101.1 - 0.018 14.1 0.0 0.056 12.5 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 RLN51101.1 - 0.021 14.6 0.2 0.054 13.2 0.0 1.9 2 1 1 3 3 2 0 AAA domain PhoH PF02562.16 RLN51101.1 - 0.023 14.2 0.2 0.11 12.0 0.0 2.2 3 0 0 3 3 2 0 PhoH-like protein AAA_7 PF12775.7 RLN51101.1 - 0.024 14.1 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 RLN51101.1 - 0.026 13.9 0.0 0.075 12.4 0.0 1.8 2 0 0 2 2 1 0 KaiC RsgA_GTPase PF03193.16 RLN51101.1 - 0.03 14.2 0.0 0.078 12.9 0.0 1.7 2 0 0 2 2 1 0 RsgA GTPase HR1 PF02185.16 RLN51101.1 - 0.031 14.4 3.7 0.068 13.3 3.7 1.6 1 0 0 1 1 1 0 Hr1 repeat AAA_11 PF13086.6 RLN51101.1 - 0.031 14.1 0.1 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 RLN51101.1 - 0.043 13.4 0.1 0.12 11.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain DASH_Dad2 PF08654.10 RLN51101.1 - 0.049 14.0 0.4 0.14 12.6 0.5 1.6 2 0 0 2 2 1 0 DASH complex subunit Dad2 Tropomyosin PF00261.20 RLN51101.1 - 0.057 12.8 1.8 0.092 12.1 1.8 1.2 1 0 0 1 1 1 0 Tropomyosin AAA_19 PF13245.6 RLN51101.1 - 0.063 13.6 0.2 0.34 11.3 0.1 2.3 3 0 0 3 3 1 0 AAA domain Zeta_toxin PF06414.12 RLN51101.1 - 0.077 12.3 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF16 PF01519.16 RLN51101.1 - 0.087 13.3 0.4 0.6 10.6 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF4618 PF15397.6 RLN51101.1 - 0.11 12.0 2.7 0.16 11.3 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF2075 PF09848.9 RLN51101.1 - 0.13 11.5 0.1 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 RLN51101.1 - 0.13 12.3 0.0 0.42 10.7 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 RLN51101.1 - 0.14 12.6 0.1 0.85 10.1 0.0 2.1 2 0 0 2 2 2 0 ABC transporter DUF2072 PF09845.9 RLN51101.1 - 0.17 12.1 0.4 0.29 11.4 0.4 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein SlyX PF04102.12 RLN51101.1 - 0.6 10.8 4.8 0.27 11.9 2.0 1.9 2 0 0 2 2 1 0 SlyX TolA_bind_tri PF16331.5 RLN51101.1 - 4.2 7.5 10.1 2.1 8.5 6.3 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation Glyco_hydro_1 PF00232.18 RLN51112.1 - 2.9e-117 391.9 0.4 3.6e-117 391.6 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 RLN51112.1 - 0.0098 15.3 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Anoctamin PF04547.12 RLN51113.1 - 8.8e-10 38.0 3.3 8.6e-08 31.4 3.3 2.2 1 1 0 1 1 1 1 Calcium-activated chloride channel TMC PF07810.13 RLN51113.1 - 0.00059 20.4 0.1 0.00059 20.4 0.1 3.6 5 1 1 6 6 6 1 TMC domain CwsA PF10814.8 RLN51113.1 - 5.2 7.3 5.4 7.7 6.7 0.2 2.5 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA Tim17 PF02466.19 RLN51115.1 - 2.6e-19 69.6 0.3 3.7e-19 69.2 0.3 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family APH_6_hur PF04655.14 RLN51115.1 - 0.02 14.3 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Dynein_light PF01221.18 RLN51116.1 - 5.4e-24 84.3 0.0 7.6e-14 51.8 0.1 2.4 2 0 0 2 2 2 2 Dynein light chain type 1 DUF3646 PF12362.8 RLN51116.1 - 0.09 13.1 0.0 7.9 6.8 0.0 2.4 2 0 0 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal Toxin-deaminase PF14424.6 RLN51116.1 - 0.091 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases Ank_2 PF12796.7 RLN51164.1 - 4.1e-30 104.2 11.5 4.7e-10 39.9 0.2 6.1 4 1 0 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 RLN51164.1 - 7.3e-28 95.8 26.6 1.1e-09 38.3 0.1 9.9 10 1 0 10 10 10 4 Ankyrin repeat Ank_4 PF13637.6 RLN51164.1 - 2.8e-24 85.1 10.6 4.7e-08 33.4 0.1 8.0 6 2 2 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN51164.1 - 9.1e-17 59.5 21.2 9.4e-07 28.7 0.0 10.3 11 0 0 11 11 11 4 Ankyrin repeat Ank_5 PF13857.6 RLN51164.1 - 3.9e-16 58.9 11.4 2.4e-08 34.1 0.2 7.2 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Mac PF12464.8 RLN51164.1 - 0.051 13.8 0.4 0.27 11.5 0.1 2.5 2 0 0 2 2 2 0 Maltose acetyltransferase DUF5446 PF17522.2 RLN51164.1 - 0.09 13.0 5.1 0.28 11.4 0.4 3.3 2 0 0 2 2 2 0 Family of unknown function (DUF5446) GAS PF13851.6 RLN51164.1 - 4.3 6.6 23.9 0.22 10.9 5.0 2.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Glyco_hydro_31 PF01055.26 RLN51165.1 - 8.2e-152 506.4 1.0 1.1e-151 506.0 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 RLN51165.1 - 1.6e-28 99.2 0.6 3.4e-28 98.1 0.6 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 RLN51165.1 - 4.4e-08 33.3 0.1 2.1e-07 31.1 0.1 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like zf-HIT PF04438.16 RLN51165.1 - 0.77 9.7 6.0 1.3 9.0 6.0 1.4 1 0 0 1 1 1 0 HIT zinc finger LRR_4 PF12799.7 RLN51166.1 - 0.02 15.3 0.3 10 6.7 0.1 4.5 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Peptidase_S64 PF08192.11 RLN51167.1 - 2 6.8 7.1 2.6 6.4 7.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 Pox_A32 PF04665.12 RLN51168.1 - 0.084 12.3 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein DUF1298 PF06974.13 RLN51171.1 - 1.8e-29 102.5 0.8 1.4e-28 99.7 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 RLN51171.1 - 1.3e-15 57.9 0.5 2.4e-15 57.0 0.3 1.6 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain ANAPC5 PF12862.7 RLN51172.1 - 2.2e-24 85.3 0.0 1.1e-23 83.1 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_MalT PF17874.1 RLN51172.1 - 0.00017 21.1 6.2 0.079 12.3 0.1 3.4 2 1 1 3 3 3 3 MalT-like TPR region ANAPC3 PF12895.7 RLN51172.1 - 0.0042 17.3 3.0 1.5 9.1 0.0 3.8 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 Ferritin PF00210.24 RLN51172.1 - 0.055 13.4 0.0 0.37 10.7 0.0 2.3 2 0 0 2 2 2 0 Ferritin-like domain TPR_19 PF14559.6 RLN51172.1 - 0.15 12.6 1.3 15 6.2 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Mannosyl_trans3 PF11051.8 RLN51173.1 - 1e-26 93.9 0.1 5.8e-16 58.6 0.0 2.2 2 0 0 2 2 2 2 Mannosyltransferase putative Sec23_trunk PF04811.15 RLN51174.1 - 1e-43 149.7 0.0 1.4e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 RLN51174.1 - 4.4e-20 71.4 0.3 1.2e-19 70.0 0.3 1.8 1 1 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 RLN51174.1 - 1e-19 71.0 0.0 1.9e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 RLN51174.1 - 1.4e-13 50.6 3.4 3.6e-13 49.3 3.4 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 RLN51174.1 - 0.022 14.6 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 Gelsolin repeat Spt20 PF12090.8 RLN51174.1 - 5.3 6.6 10.3 11 5.6 10.3 1.4 1 0 0 1 1 1 0 Spt20 family PI3_PI4_kinase PF00454.27 RLN51175.1 - 1.2e-42 146.5 0.0 2.5e-42 145.5 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SMG1 PF15785.5 RLN51175.1 - 1.4e-20 73.3 2.2 1.3e-15 56.8 0.1 2.8 3 0 0 3 3 3 2 Serine/threonine-protein kinase smg-1 FATC PF02260.20 RLN51175.1 - 2e-13 49.9 1.0 2e-13 49.9 1.0 2.2 2 0 0 2 2 2 1 FATC domain FAT PF02259.23 RLN51175.1 - 0.00038 19.8 0.0 0.00093 18.5 0.0 1.6 1 0 0 1 1 1 1 FAT domain FRB_dom PF08771.11 RLN51175.1 - 0.034 14.6 0.3 1.1 9.7 0.3 3.3 1 1 0 1 1 1 0 FKBP12-rapamycin binding domain Peptidase_M48 PF01435.18 RLN51176.1 - 1.1e-31 110.1 0.0 2.4e-31 109.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 E1-E2_ATPase PF00122.20 RLN51176.1 - 1.8e-26 92.8 1.2 4.9e-26 91.4 0.1 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 RLN51176.1 - 7.7e-09 36.1 2.0 0.00029 21.2 0.1 3.7 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 RLN51176.1 - 9.2e-07 29.0 0.2 2.9e-06 27.4 0.2 1.9 1 0 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.26 RLN51176.1 - 0.003 17.2 0.0 0.0067 16.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 RLN51176.1 - 0.037 14.1 0.0 0.097 12.8 0.0 1.7 1 0 0 1 1 1 0 Cation transport ATPase (P-type) 2-Hacid_dh_C PF02826.19 RLN51177.1 - 3.4e-36 124.3 0.0 5.7e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ACT PF01842.25 RLN51177.1 - 4.4e-05 23.2 0.0 0.00012 21.7 0.0 1.9 1 0 0 1 1 1 1 ACT domain 2-Hacid_dh PF00389.30 RLN51177.1 - 5.7e-05 22.8 0.0 0.00037 20.2 0.0 2.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 RLN51177.1 - 0.02 14.2 0.2 0.1 11.9 0.1 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ACT_4 PF13291.6 RLN51177.1 - 0.021 15.4 0.0 0.073 13.7 0.0 1.9 1 0 0 1 1 1 0 ACT domain DUF3638 PF12340.8 RLN51178.1 - 6.2e-31 107.5 0.3 1.6e-29 102.9 0.3 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 RLN51178.1 - 5e-15 54.6 0.0 9.6e-15 53.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) NUC130_3NT PF08158.12 RLN51178.1 - 0.012 16.0 0.3 0.048 14.0 0.3 2.2 1 0 0 1 1 1 0 NUC130/3NT domain EF-hand_8 PF13833.6 RLN51178.1 - 0.022 14.6 0.0 0.1 12.5 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 RLN51178.1 - 0.049 13.2 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 RLN51178.1 - 0.06 12.9 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 EF hand LrgA PF03788.14 RLN51178.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 LrgA family EF-hand_6 PF13405.6 RLN51178.1 - 0.15 12.0 0.0 0.55 10.3 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain EutK_C PF16365.5 RLN51178.1 - 0.21 11.7 0.8 2.7 8.1 0.1 2.7 2 0 0 2 2 2 0 Ethanolamine utilization protein EutK C-terminus zf-RanBP PF00641.18 RLN51178.1 - 0.84 9.0 20.1 1.5 8.2 1.5 3.4 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others TMEM135_C_rich PF15982.5 RLN51179.1 - 3e-05 24.6 0.5 7.4e-05 23.4 0.5 1.6 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 KIX_2 PF16987.5 RLN51179.1 - 5.6e-05 23.1 0.0 0.0002 21.3 0.0 2.0 1 0 0 1 1 1 1 KIX domain DUF1041 PF06292.17 RLN51179.1 - 0.012 16.0 0.4 0.032 14.6 0.4 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) Glyco_hydro_18 PF00704.28 RLN51179.1 - 0.091 12.5 0.0 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolases family 18 Papilloma_E5 PF03025.14 RLN51179.1 - 1 9.5 2.8 13 6.1 0.7 2.4 2 0 0 2 2 2 0 Papillomavirus E5 DUF2951 PF11166.8 RLN51184.1 - 0.15 12.3 4.3 0.46 10.7 2.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) FAM184 PF15665.5 RLN51184.1 - 0.21 11.3 9.7 0.76 9.5 6.3 2.4 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DivIC PF04977.15 RLN51184.1 - 0.48 10.2 0.1 0.48 10.2 0.1 2.9 2 1 0 2 2 2 0 Septum formation initiator GCV_H PF01597.19 RLN51185.1 - 0.012 15.5 0.0 0.066 13.1 0.0 1.9 1 1 0 1 1 1 0 Glycine cleavage H-protein AOX PF01786.17 RLN51187.1 - 1.5e-34 119.5 0.0 2.3e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Alternative oxidase Methyltransf_25 PF13649.6 RLN51188.1 - 8.8e-09 36.0 0.0 2e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN51188.1 - 1.8e-08 34.9 0.0 4e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN51188.1 - 5.2e-05 23.1 0.0 7.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN51188.1 - 0.00019 22.1 0.0 0.00036 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN51188.1 - 0.00025 20.5 0.0 0.00075 18.9 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 RLN51188.1 - 0.00039 20.2 0.0 0.00055 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain AOX PF01786.17 RLN51189.1 - 9.3e-35 120.2 0.1 1.9e-34 119.2 0.0 1.5 2 0 0 2 2 2 1 Alternative oxidase DIOX_N PF14226.6 RLN51199.1 - 5.6e-21 75.5 0.0 1.3e-20 74.3 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 RLN51199.1 - 7.3e-19 68.1 0.0 1.1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Arrestin_C PF02752.22 RLN51200.1 - 7.2e-11 42.7 0.0 1.3e-08 35.3 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 RLN51200.1 - 2e-06 28.0 0.0 0.00016 21.8 0.0 2.6 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 RLN51200.1 - 0.02 14.6 0.0 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 Arrestin_N terminal like CAP PF00188.26 RLN51201.1 - 4.2e-15 56.7 1.5 6.1e-15 56.2 1.5 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Jnk-SapK_ap_N PF09744.9 RLN51202.1 - 0.0054 17.0 4.7 0.0054 17.0 4.7 3.8 2 1 2 4 4 4 1 JNK_SAPK-associated protein-1 DUF2951 PF11166.8 RLN51202.1 - 0.088 13.0 6.1 0.18 12.0 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) Seryl_tRNA_N PF02403.22 RLN51202.1 - 1.9 8.8 30.7 0.027 14.7 3.3 3.6 2 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Nsp1_C PF05064.13 RLN51204.1 - 5.5e-08 32.6 1.2 5.5e-08 32.6 1.2 2.2 1 1 1 2 2 2 1 Nsp1-like C-terminal region Snapin_Pallidin PF14712.6 RLN51204.1 - 0.0011 19.3 13.6 0.0049 17.3 7.7 3.1 1 1 3 4 4 4 2 Snapin/Pallidin Herpes_UL25 PF01499.16 RLN51204.1 - 0.0053 15.3 1.3 0.0061 15.2 1.3 1.1 1 0 0 1 1 1 1 Herpesvirus UL25 family DUF4164 PF13747.6 RLN51204.1 - 0.014 15.6 7.0 0.25 11.7 1.9 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) DUF1664 PF07889.12 RLN51204.1 - 0.016 15.3 9.7 0.16 12.0 5.1 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DASH_Dad2 PF08654.10 RLN51204.1 - 0.016 15.6 5.7 1.1 9.7 1.1 2.5 2 1 0 2 2 2 0 DASH complex subunit Dad2 FlaC_arch PF05377.11 RLN51204.1 - 0.02 15.3 6.0 0.45 10.9 0.1 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) TACC_C PF05010.14 RLN51204.1 - 0.02 14.7 7.3 0.023 14.5 6.6 1.3 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Laminin_II PF06009.12 RLN51204.1 - 0.021 14.8 8.6 0.055 13.5 3.1 2.1 1 1 1 2 2 2 0 Laminin Domain II Fez1 PF06818.15 RLN51204.1 - 0.021 15.3 6.4 0.027 14.9 6.4 1.1 1 0 0 1 1 1 0 Fez1 CHAD PF05235.14 RLN51204.1 - 0.031 14.3 0.6 0.038 14.0 0.6 1.2 1 0 0 1 1 1 0 CHAD domain Syntaxin PF00804.25 RLN51204.1 - 0.035 13.8 6.0 0.4 10.3 0.5 2.0 1 1 1 2 2 2 0 Syntaxin Spc7 PF08317.11 RLN51204.1 - 0.04 12.8 9.2 0.12 11.3 9.2 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF948 PF06103.11 RLN51204.1 - 0.08 13.2 7.9 2.6 8.4 7.4 3.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1978 PF09321.10 RLN51204.1 - 0.09 12.1 6.6 0.18 11.1 6.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1978) DMSP_lyase PF16867.5 RLN51204.1 - 0.11 12.1 0.7 1.1 8.9 0.3 2.0 1 1 1 2 2 2 0 Dimethlysulfonioproprionate lyase DASH_Dad4 PF08650.10 RLN51204.1 - 0.17 11.9 6.2 0.52 10.3 1.1 3.1 2 2 1 3 3 3 0 DASH complex subunit Dad4 BST2 PF16716.5 RLN51204.1 - 0.22 12.1 6.6 0.12 13.0 1.4 2.2 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 TMPIT PF07851.13 RLN51204.1 - 0.22 10.7 4.8 0.47 9.6 4.8 1.6 1 1 0 1 1 1 0 TMPIT-like protein Mod_r PF07200.13 RLN51204.1 - 0.23 11.5 8.6 2.8 8.1 0.7 2.2 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein KIP1 PF07765.12 RLN51204.1 - 0.26 11.4 4.8 1.6 8.9 0.7 2.4 2 0 0 2 2 2 0 KIP1-like protein DUF4200 PF13863.6 RLN51204.1 - 0.36 11.2 6.0 0.84 10.1 4.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Fib_alpha PF08702.10 RLN51204.1 - 0.42 10.8 8.9 2.7 8.2 2.2 2.3 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family CLZ PF16526.5 RLN51204.1 - 0.44 10.9 9.0 2.4 8.6 0.6 2.9 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Frataxin_Cyay PF01491.16 RLN51204.1 - 0.46 10.6 5.4 1.8 8.7 0.8 2.2 1 1 1 2 2 2 0 Frataxin-like domain Enkurin PF13864.6 RLN51204.1 - 0.5 10.8 4.8 0.67 10.4 1.2 2.3 1 1 1 2 2 2 0 Calmodulin-binding DUF4795 PF16043.5 RLN51204.1 - 0.57 9.8 10.7 1.5 8.4 10.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PRKG1_interact PF15898.5 RLN51204.1 - 0.58 11.1 7.1 0.44 11.5 5.3 1.7 2 0 0 2 2 1 0 cGMP-dependent protein kinase interacting domain UPF0449 PF15136.6 RLN51204.1 - 0.97 9.9 6.4 4.1 7.9 4.0 2.4 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Prominin PF05478.11 RLN51204.1 - 1.1 7.1 7.6 3.1 5.7 7.8 1.4 1 1 0 1 1 1 0 Prominin DUF16 PF01519.16 RLN51204.1 - 1.2 9.6 9.1 2.4 8.7 8.3 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 bZIP_1 PF00170.21 RLN51204.1 - 1.3 9.2 8.3 1.1 9.5 0.5 2.6 3 0 0 3 3 2 0 bZIP transcription factor XhlA PF10779.9 RLN51204.1 - 2.8 8.2 6.6 4.7 7.5 0.3 2.5 2 1 0 2 2 2 0 Haemolysin XhlA Tweety PF04906.13 RLN51204.1 - 3 6.4 6.1 2.9 6.5 0.5 2.0 1 1 1 2 2 2 0 Tweety KELK PF15796.5 RLN51204.1 - 4.6 7.8 8.3 1.4 9.4 2.5 2.7 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Cnn_1N PF07989.11 RLN51204.1 - 9.3 6.5 10.3 16 5.7 6.6 2.6 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 UQ_con PF00179.26 RLN51206.1 - 1.2e-10 41.2 0.1 6.3e-09 35.6 0.0 2.9 1 1 1 2 2 2 1 Ubiquitin-conjugating enzyme DUF4477 PF14780.6 RLN51206.1 - 1.2e-05 25.0 7.8 0.0001 22.0 7.9 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4477) DprA_WH PF17782.1 RLN51206.1 - 0.0042 17.2 0.3 0.021 14.9 0.1 2.2 2 0 0 2 2 2 1 DprA winged helix domain Nod1 PF17114.5 RLN51206.1 - 0.043 14.0 0.2 0.16 12.1 0.1 1.9 2 1 0 2 2 2 0 Gef2-related medial cortical node protein Nod1 PBS_linker_poly PF00427.21 RLN51206.1 - 0.15 12.1 0.2 0.29 11.2 0.2 1.4 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide Proteasome PF00227.26 RLN51216.1 - 3e-13 49.7 0.0 3.5e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF3177 PF11375.8 RLN51216.1 - 0.16 11.8 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) Glyco_hydro_1 PF00232.18 RLN51217.1 - 7.5e-114 380.6 0.2 8.9e-114 380.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_1 PF00232.18 RLN51218.1 - 1.6e-123 412.5 0.1 1.9e-123 412.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF1771 PF08590.10 RLN51219.1 - 8.1e-13 48.5 13.8 9.2e-12 45.2 9.1 3.6 2 1 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 RLN51219.1 - 1.1e-10 41.7 0.3 9e-10 38.8 0.1 2.4 2 0 0 2 2 2 1 Smr domain zf_CCCH_4 PF18345.1 RLN51219.1 - 0.94 9.6 3.5 0.63 10.2 0.2 2.2 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH_4 PF18044.1 RLN51219.1 - 2.2 8.2 4.8 1 9.3 0.5 2.2 2 0 0 2 2 2 0 CCCH-type zinc finger CAP_N PF01213.19 RLN51219.1 - 3.9 6.9 6.9 3.9 6.9 5.2 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Glyco_hydro_1 PF00232.18 RLN51220.1 - 0 1213.7 0.7 9.6e-125 416.5 0.1 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 1 Cellulase PF00150.18 RLN51220.1 - 9.9e-09 35.0 0.1 0.0051 16.3 0.0 3.9 4 0 0 4 4 4 3 Cellulase (glycosyl hydrolase family 5) Lipase_GDSL_2 PF13472.6 RLN51220.1 - 9.7e-08 32.6 0.0 0.079 13.3 0.0 3.7 3 0 0 3 3 3 3 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_1 PF00232.18 RLN51221.1 - 2.6e-113 378.8 0.0 3.3e-113 378.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 RLN51221.1 - 0.029 13.8 0.2 0.056 12.9 0.0 1.5 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) SBF PF01758.16 RLN51224.1 - 1e-08 35.1 1.6 1e-08 35.1 1.6 1.0 1 0 0 1 1 1 1 Sodium Bile acid symporter family MIF4G PF02854.19 RLN51226.1 - 3.1e-18 66.2 0.0 4.4e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 MIF4G domain PNP_phzG_C PF10590.9 RLN51226.1 - 0.03 14.4 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region SLED PF12140.8 RLN51226.1 - 0.1 13.1 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 SLED domain AAA_16 PF13191.6 RLN51227.1 - 0.0047 17.3 0.1 0.0067 16.8 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain ATPase PF06745.13 RLN51227.1 - 0.016 14.6 0.0 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 RLN51227.1 - 0.057 13.7 0.0 0.072 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain KdpD PF02702.17 RLN51227.1 - 0.25 10.8 0.0 0.31 10.5 0.0 1.1 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain Sod_Fe_C PF02777.18 RLN51228.1 - 4.5e-39 132.7 0.6 1e-38 131.6 0.0 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 RLN51228.1 - 9.8e-31 106.1 2.2 1.5e-30 105.4 2.2 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ChaB PF06150.12 RLN51228.1 - 0.092 13.3 0.9 0.092 13.3 0.9 1.9 2 0 0 2 2 2 0 ChaB dCMP_cyt_deam_1 PF00383.23 RLN51228.1 - 0.12 12.3 0.2 0.31 10.9 0.2 1.7 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Palm_thioest PF02089.15 RLN51229.1 - 0.0003 20.7 0.0 0.00054 19.9 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 RLN51229.1 - 0.0019 17.9 0.4 0.031 13.9 0.1 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN51229.1 - 0.0066 17.1 0.1 0.012 16.3 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 RLN51229.1 - 0.0077 15.8 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 RLN51229.1 - 0.056 12.9 0.0 0.33 10.4 0.0 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 RLN51229.1 - 0.061 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 PGAP1-like protein Lipase_2 PF01674.18 RLN51229.1 - 0.14 11.7 0.2 6.5 6.2 0.0 2.6 2 0 0 2 2 2 0 Lipase (class 2) Palm_thioest PF02089.15 RLN51230.1 - 0.00021 21.2 0.0 0.0004 20.3 0.0 1.7 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 RLN51230.1 - 0.0009 19.0 0.6 0.085 12.5 0.1 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold DUF676 PF05057.14 RLN51230.1 - 0.082 12.4 0.0 0.57 9.6 0.0 2.3 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF2613 PF11021.8 RLN51231.1 - 0.95 9.6 6.0 3.3 7.9 6.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) RNA_pol_I_A49 PF06870.12 RLN51232.1 - 5.6e-69 232.8 0.4 7.1e-69 232.5 0.4 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor F_actin_cap_B PF01115.17 RLN51233.1 - 2.5e-96 321.9 0.0 2.9e-96 321.7 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit FAD_binding_3 PF01494.19 RLN51241.1 - 5.4e-20 71.9 0.2 7.6e-10 38.6 0.1 2.3 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 RLN51241.1 - 1e-06 28.0 0.0 1.6e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 RLN51241.1 - 2.3e-06 26.7 0.0 0.15 10.9 0.0 3.1 3 0 0 3 3 3 3 Tryptophan halogenase DAO PF01266.24 RLN51241.1 - 2e-05 24.4 0.4 6.6e-05 22.6 0.3 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RLN51241.1 - 0.00022 20.6 0.0 0.028 13.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RLN51241.1 - 0.00096 19.3 0.0 0.0028 17.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 RLN51241.1 - 0.0047 16.0 0.7 1.4 7.9 0.3 2.3 1 1 1 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 RLN51241.1 - 0.013 16.0 0.0 0.031 14.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 RLN51241.1 - 0.056 13.7 0.0 0.18 12.0 0.0 1.9 2 0 0 2 2 1 0 TrkA-N domain NAD_binding_9 PF13454.6 RLN51241.1 - 0.078 13.0 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 RLN51241.1 - 0.31 10.1 2.4 1 8.4 2.4 2.0 1 1 0 1 1 1 0 FAD binding domain CSRNP_N PF16019.5 RLN51242.1 - 0.011 15.7 3.6 0.017 15.0 0.0 2.3 2 1 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus RR_TM4-6 PF06459.12 RLN51242.1 - 3.5 7.4 8.3 6.3 6.5 8.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SUI1 PF01253.22 RLN51243.1 - 1.2e-18 67.4 0.2 3.1e-18 66.1 0.2 1.8 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF4637 PF15470.6 RLN51243.1 - 0.0088 15.8 3.8 0.02 14.6 3.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4637) eIF-3c_N PF05470.12 RLN51243.1 - 0.07 11.4 3.2 0.089 11.1 3.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DNA_pol_phi PF04931.13 RLN51243.1 - 0.15 10.2 12.3 0.28 9.2 12.3 1.4 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 RLN51243.1 - 2.8 7.3 10.9 4.8 6.5 10.9 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Astro_capsid_p PF12226.8 RLN51243.1 - 4.1 6.5 7.7 6.7 5.8 7.7 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein FAM176 PF14851.6 RLN51243.1 - 5.1 6.8 6.0 1.2 8.8 2.5 1.8 2 0 0 2 2 2 0 FAM176 family Cwf_Cwc_15 PF04889.12 RLN51243.1 - 5.9 6.5 15.2 0.31 10.7 8.4 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein LicD PF04991.13 RLN51245.1 - 4.3e-19 69.6 0.9 3.1e-15 56.9 0.4 2.1 1 1 0 2 2 2 2 LicD family SrfB PF07520.11 RLN51245.1 - 0.21 9.4 0.0 1.4 6.7 0.0 1.8 2 0 0 2 2 2 0 Virulence factor SrfB PIG-P PF08510.12 RLN51246.1 - 1.3e-24 86.4 1.4 1.3e-24 86.4 1.4 1.8 2 0 0 2 2 2 1 PIG-P DPM2 PF07297.12 RLN51246.1 - 0.066 13.5 3.3 0.14 12.5 3.3 1.5 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Striatin PF08232.12 RLN51246.1 - 0.12 13.0 0.7 0.17 12.5 0.7 1.2 1 0 0 1 1 1 0 Striatin family Voltage_CLC PF00654.20 RLN51247.1 - 2.9e-70 237.3 19.6 8.8e-69 232.4 6.7 3.0 1 1 2 3 3 3 2 Voltage gated chloride channel CBS PF00571.28 RLN51247.1 - 1.2e-06 28.8 0.0 0.00082 19.8 0.0 2.6 2 0 0 2 2 2 2 CBS domain HNF_C PF09354.10 RLN51250.1 - 0.22 12.6 0.3 0.22 12.6 0.3 3.0 3 1 0 3 3 3 0 HNF3 C-terminal domain FYVE PF01363.21 RLN51252.1 - 2.7e-07 30.6 12.8 8.2e-07 29.1 12.8 1.7 1 1 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN51252.1 - 0.00093 19.4 6.4 0.0024 18.1 6.4 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger zf-RING_UBOX PF13445.6 RLN51252.1 - 0.59 10.2 5.5 9.6 6.3 2.8 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 RLN51252.1 - 1.1 9.6 9.7 3.4 8.1 9.8 1.9 1 1 1 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 RLN51252.1 - 7.8 6.5 11.4 24 5.0 11.4 1.9 1 1 0 1 1 1 0 zinc-RING finger domain DUF1664 PF07889.12 RLN51253.1 - 0.0055 16.8 3.0 0.0055 16.8 3.0 6.9 8 0 0 8 8 8 2 Protein of unknown function (DUF1664) Baculo_F PF12259.8 RLN51253.1 - 1.8 7.0 5.5 1.2 7.6 0.5 2.2 2 0 0 2 2 2 0 Baculovirus F protein PIP5K PF01504.18 RLN51254.1 - 2.2e-07 30.4 0.5 3.3e-07 29.8 0.1 1.4 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Sugar_tr PF00083.24 RLN51255.1 - 5.9e-38 130.9 23.7 6e-37 127.6 23.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN51255.1 - 5.5e-37 127.5 41.0 3.7e-33 114.9 24.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DEP PF00610.21 RLN51256.1 - 8.1e-20 70.7 0.3 6.4e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) BUD22 PF09073.10 RLN51256.1 - 0.07 12.5 10.9 0.13 11.6 10.9 1.3 1 0 0 1 1 1 0 BUD22 B_solenoid_ydck PF18836.1 RLN51256.1 - 0.072 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Beta solenoid repeat from YDCK Presenilin PF01080.17 RLN51256.1 - 3.4 6.3 5.6 5.2 5.7 5.6 1.2 1 0 0 1 1 1 0 Presenilin Ceramidase_alk PF04734.13 RLN51257.1 - 2.2e-138 462.1 0.0 5.4e-137 457.5 0.0 2.0 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 RLN51257.1 - 4.7e-35 120.9 1.3 8.5e-35 120.1 0.1 1.9 2 0 0 2 2 2 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Glyco_hydro_3 PF00933.21 RLN51267.1 - 5.5e-45 154.1 0.0 6.1e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain FYVE PF01363.21 RLN51282.1 - 7e-16 58.1 13.6 2e-15 56.6 13.6 1.8 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN51282.1 - 0.00076 19.7 4.3 0.0018 18.4 4.3 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger PT PF04886.12 RLN51284.1 - 2.8e-12 45.9 54.3 7.1e+02 -0.1 54.3 3.1 1 1 0 1 1 1 0 PT repeat DUF4366 PF14283.6 RLN51284.1 - 0.04 14.0 0.4 0.04 14.0 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) TMEM51 PF15345.6 RLN51284.1 - 0.067 13.0 0.3 0.067 13.0 0.3 2.0 2 1 0 2 2 2 0 Transmembrane protein 51 Glycoprotein_G PF00802.19 RLN51284.1 - 2 7.7 13.0 0.85 8.9 10.0 1.8 2 0 0 2 2 2 0 Pneumovirus attachment glycoprotein G MULE PF10551.9 RLN51305.1 - 5.7e-12 45.9 0.9 8.2e-12 45.4 0.1 1.7 2 0 0 2 2 2 1 MULE transposase domain DUF5596 PF18082.1 RLN51305.1 - 0.053 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) Glyco_hydro_30 PF02055.16 RLN51308.1 - 4.7e-39 134.3 0.2 6.1e-39 134.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 RLN51308.1 - 7.1e-11 42.2 0.3 1.2e-10 41.5 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Arm PF00514.23 RLN51329.1 - 3.7e-26 90.3 9.2 0.0024 17.8 0.0 10.3 10 0 0 10 10 10 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN51329.1 - 9.8e-11 41.9 18.0 0.0035 17.8 0.3 6.6 6 2 0 6 6 6 4 HEAT-like repeat Pkinase_Tyr PF07714.17 RLN51329.1 - 1.9e-10 40.4 0.0 4.2e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN51329.1 - 1.8e-08 34.1 0.0 4.4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain HEAT_2 PF13646.6 RLN51329.1 - 1.8e-06 28.3 25.7 0.0035 17.7 0.2 6.7 3 2 3 7 7 7 5 HEAT repeats HEAT PF02985.22 RLN51329.1 - 2.9e-05 24.0 7.2 5.5 7.5 0.0 7.9 7 1 0 7 7 7 1 HEAT repeat NFACT-R_2 PF18297.1 RLN51329.1 - 0.013 15.7 0.5 0.68 10.2 0.0 3.5 1 1 3 4 4 4 0 NFACT protein RNA binding domain RPAP1_C PF08620.10 RLN51329.1 - 0.092 12.9 0.1 23 5.2 0.0 4.2 5 0 0 5 5 5 0 RPAP1-like, C-terminal DUF294_C PF10335.9 RLN51329.1 - 1.8 8.4 5.1 3.5 7.4 0.1 3.4 3 1 1 4 4 4 0 Putative nucleotidyltransferase substrate binding domain Acetyltransf_1 PF00583.25 RLN51364.1 - 6e-11 42.6 0.0 7.6e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RLN51364.1 - 3.7e-09 36.9 0.0 4.8e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN51364.1 - 6.4e-09 35.7 0.0 9.4e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 RLN51364.1 - 1.1e-08 35.1 0.0 1.3e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 RLN51364.1 - 0.0032 17.5 0.1 0.0073 16.4 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PPR_long PF17177.4 RLN51419.1 - 1.7e-39 135.4 0.4 2.8e-39 134.7 0.4 1.3 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP Elicitin PF00964.17 RLN51419.1 - 2.1e-13 50.2 5.1 2.1e-13 50.2 5.1 2.9 3 1 0 3 3 3 1 Elicitin PPR_2 PF13041.6 RLN51419.1 - 2.7e-12 46.7 0.0 0.002 18.3 0.0 3.7 3 0 0 3 3 3 3 PPR repeat family PPR PF01535.20 RLN51419.1 - 2.7e-11 42.9 0.6 0.16 12.3 0.0 5.4 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.6 RLN51419.1 - 9.6e-07 28.8 0.1 0.02 14.9 0.0 3.0 2 1 1 3 3 3 2 Pentatricopeptide repeat domain IL17_R_N PF15037.6 RLN51419.1 - 0.074 12.0 1.0 0.52 9.2 0.1 2.4 2 1 1 3 3 3 0 Interleukin-17 receptor extracellular region SWI-SNF_Ssr4 PF08549.10 RLN51419.1 - 0.47 9.0 21.8 0.61 8.7 21.8 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Hamartin PF04388.12 RLN51419.1 - 0.95 8.0 28.3 1.2 7.7 28.3 1.1 1 0 0 1 1 1 0 Hamartin protein DUF5325 PF17259.2 RLN51425.1 - 0.51 10.3 5.1 0.48 10.3 2.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5325) SR-25 PF10500.9 RLN51426.1 - 0.54 9.8 13.1 0.038 13.6 8.3 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 RLN51426.1 - 1 9.3 7.3 1.3 9.0 7.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MGS PF02142.22 RLN51441.1 - 2.5e-15 56.4 0.0 3.3e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 MGS-like domain BRAP2 PF07576.12 RLN51442.1 - 1e-24 86.6 0.5 1.8e-24 85.9 0.5 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 RLN51442.1 - 1.7e-19 69.9 7.9 4.6e-19 68.5 7.9 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 RLN51442.1 - 1.1e-07 32.1 7.9 1.1e-07 32.1 7.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN51442.1 - 3e-07 30.2 6.5 3e-07 30.2 6.5 2.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN51442.1 - 8.2e-05 22.3 3.5 8.2e-05 22.3 3.5 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 RLN51442.1 - 0.00064 19.5 16.4 0.013 15.4 4.5 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN51442.1 - 0.00075 19.3 5.8 0.00075 19.3 5.8 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN51442.1 - 0.00088 19.5 5.5 0.00088 19.5 5.5 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger domain HPS3_N PF14761.6 RLN51442.1 - 0.0012 18.5 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3 zf-RING_UBOX PF13445.6 RLN51442.1 - 0.006 16.6 1.7 0.006 16.6 1.7 2.9 1 1 1 2 2 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 RLN51442.1 - 0.5 10.5 7.3 0.37 10.9 5.3 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Exonuc_VII_L PF02601.15 RLN51442.1 - 2.2 7.8 8.2 3.3 7.2 8.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit RuvC PF02075.17 RLN51443.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC DEDD_Tnp_IS110 PF01548.17 RLN51443.1 - 0.17 11.7 0.2 12 5.8 0.0 2.3 2 0 0 2 2 2 0 Transposase DUF21 PF01595.20 RLN51444.1 - 1e-31 110.0 5.7 1.4e-31 109.5 4.8 1.7 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain Hint PF01079.20 RLN51444.1 - 9.3e-11 41.6 0.0 1.2e-08 34.8 0.0 2.3 1 1 0 1 1 1 1 Hint module Kelch_1 PF01344.25 RLN51444.1 - 0.00013 21.4 1.6 0.16 11.6 0.0 4.4 4 0 0 4 4 4 1 Kelch motif CBS PF00571.28 RLN51444.1 - 0.00021 21.7 0.6 0.16 12.4 0.0 3.0 3 0 0 3 3 3 2 CBS domain Kelch_6 PF13964.6 RLN51444.1 - 0.031 14.6 5.7 1.7 9.0 0.3 3.9 4 0 0 4 4 4 0 Kelch motif Choline_transpo PF04515.12 RLN51445.1 - 3e-62 210.7 19.2 3e-62 210.7 19.2 2.1 1 1 1 2 2 2 1 Plasma-membrane choline transporter PDZ_6 PF17820.1 RLN51446.1 - 4.2e-08 32.9 0.1 0.003 17.4 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 RLN51446.1 - 1.3e-05 25.5 0.0 0.073 13.4 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 RLN51446.1 - 2.2e-05 24.7 0.0 0.1 13.0 0.0 2.4 2 0 0 2 2 2 2 PDZ domain FAM219A PF15260.6 RLN51447.1 - 0.15 12.5 1.1 0.35 11.2 1.1 1.6 1 0 0 1 1 1 0 Protein family FAM219A Pkinase PF00069.25 RLN51448.1 - 0.028 13.8 0.0 0.03 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Myb_DNA-bind_4 PF13837.6 RLN51450.1 - 0.072 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Glutaminase PF04960.15 RLN51471.1 - 0.1 11.8 0.3 0.14 11.3 0.3 1.2 1 0 0 1 1 1 0 Glutaminase PIG-L PF02585.17 RLN51471.1 - 0.5 11.0 4.8 1.1 9.8 4.8 1.7 1 1 0 1 1 1 0 GlcNAc-PI de-N-acetylase OmpH PF03938.14 RLN51471.1 - 1.1 9.6 16.8 1.6 9.0 16.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Synaptobrevin PF00957.21 RLN51494.1 - 2.1e-15 56.3 0.7 3.2e-15 55.7 0.7 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 RLN51494.1 - 9.9e-14 51.2 0.0 1.7e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Nsp1_C PF05064.13 RLN51494.1 - 0.017 14.9 0.6 0.042 13.6 0.4 1.8 1 1 1 2 2 2 0 Nsp1-like C-terminal region PKD_channel PF08016.12 RLN51496.1 - 4.7e-29 101.3 0.7 8.4e-18 64.2 0.0 2.5 3 0 0 3 3 3 2 Polycystin cation channel TIL PF01826.17 RLN51496.1 - 0.033 14.4 7.8 0.064 13.5 7.8 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain FAM104 PF15434.6 RLN51497.1 - 0.0096 16.5 1.5 0.0096 16.5 1.5 1.9 1 1 1 2 2 2 1 Family 104 Draxin PF15550.6 RLN51497.1 - 3.7 7.3 10.5 4.5 7.1 10.5 1.0 1 0 0 1 1 1 0 Draxin Folate_rec PF03024.14 RLN51551.1 - 0.055 13.3 3.3 0.3 11.0 0.1 2.9 3 0 0 3 3 3 0 Folate receptor family DEAD PF00270.29 RLN51588.1 - 2e-06 27.7 0.0 0.0002 21.2 0.0 2.3 1 1 1 2 2 2 2 DEAD/DEAH box helicase PARG_cat PF05028.14 RLN51589.1 - 1e-91 307.8 0.0 2.1e-91 306.7 0.0 1.5 1 1 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) WXG100 PF06013.12 RLN51590.1 - 0.27 11.5 12.3 0.2 11.9 10.0 1.9 2 0 0 2 2 2 0 Proteins of 100 residues with WXG CBM_25 PF03423.13 RLN51598.1 - 1.4e-10 41.4 4.7 2.3e-10 40.7 4.3 1.5 1 1 0 1 1 1 1 Carbohydrate binding domain (family 25) CBM53 PF16760.5 RLN51598.1 - 5.1e-07 30.2 1.9 9.6e-07 29.3 1.9 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) CBM26 PF16738.5 RLN51598.1 - 0.0061 16.8 1.9 0.014 15.7 1.9 1.7 1 0 0 1 1 1 1 Starch-binding module 26 CBM_25 PF03423.13 RLN51599.1 - 1.6e-12 47.6 1.7 2.6e-12 46.9 1.5 1.5 1 1 0 1 1 1 1 Carbohydrate binding domain (family 25) CBM53 PF16760.5 RLN51599.1 - 4.1e-10 40.1 1.3 6.8e-10 39.4 1.3 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) DDE_1 PF03184.19 RLN51616.1 - 0.00036 20.2 0.0 0.00042 20.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease FYVE PF01363.21 RLN51624.1 - 5.5e-09 36.0 11.0 9.8e-09 35.2 11.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN51624.1 - 0.033 14.4 6.6 0.072 13.3 6.6 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger WW PF00397.26 RLN51624.1 - 0.22 11.7 0.0 0.48 10.5 0.0 1.5 1 0 0 1 1 1 0 WW domain Epiglycanin_TR PF05647.11 RLN51625.1 - 0.013 15.4 1.4 0.013 15.4 1.4 2.3 2 0 0 2 2 2 0 Tandem-repeating region of mucin, epiglycanin-like DNA_pol_B_2 PF03175.13 RLN51642.1 - 3.1e-16 59.3 5.0 5.6e-11 42.0 2.0 2.4 1 1 1 2 2 2 2 DNA polymerase type B, organellar and viral Dimer_Tnp_hAT PF05699.14 RLN51667.1 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 RLN51667.1 - 0.019 15.0 0.1 0.038 14.0 0.1 1.6 1 0 0 1 1 1 0 BED zinc finger RNA_polI_A34 PF08208.11 RLN51673.1 - 4.5e-07 30.2 0.4 4.5e-07 30.2 0.4 2.7 2 1 1 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 FMO-like PF00743.19 RLN51684.1 - 5e-38 130.8 0.0 3.1e-29 101.8 0.0 3.3 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 RLN51684.1 - 9.5e-15 54.6 0.0 5.2e-14 52.2 0.0 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 RLN51684.1 - 1.3e-05 24.6 0.0 1.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RLN51684.1 - 0.0017 17.5 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 RLN51684.1 - 0.015 15.5 0.0 0.058 13.6 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 RLN51684.1 - 0.025 14.6 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.19 RLN51685.1 - 1.3e-45 155.9 0.0 5.5e-38 130.7 0.0 3.0 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 RLN51685.1 - 4.1e-15 55.8 0.1 2.2e-14 53.4 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 RLN51685.1 - 1.4e-05 24.5 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RLN51685.1 - 0.001 18.3 0.1 0.0022 17.2 0.1 1.5 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 RLN51685.1 - 0.0022 17.6 0.1 0.0045 16.6 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 RLN51685.1 - 0.0028 17.7 0.2 0.31 11.0 0.1 3.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 RLN51685.1 - 0.02 15.0 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 RLN51685.1 - 0.056 12.7 0.0 0.092 12.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain CDC48_N PF02359.18 RLN51692.1 - 1.5e-13 50.7 0.1 2.4e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.17 RLN51692.1 - 1e-08 34.9 0.0 2.3e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Molydop_binding PF01568.21 RLN51692.1 - 0.016 15.3 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain PEX-2N PF09263.10 RLN51692.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal BCL_N PF04714.13 RLN51695.1 - 0.037 14.1 0.4 0.064 13.3 0.4 1.4 1 0 0 1 1 1 0 BCL7, N-terminal conserver region Pneumo_att_G PF05539.11 RLN51695.1 - 0.33 10.5 16.1 0.43 10.1 16.1 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G MFS_1 PF07690.16 RLN51696.1 - 1.6e-13 50.4 54.3 6.7e-08 31.8 22.3 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RLN51696.1 - 6.9e-10 38.1 18.0 6.9e-10 38.1 18.0 2.3 2 0 0 2 2 2 1 MFS/sugar transport protein PhzC-PhzF PF02567.16 RLN51710.1 - 1.5e-56 192.0 0.0 1.9e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Acetyltransf_1 PF00583.25 RLN51710.1 - 2.1e-09 37.6 0.0 4.4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RLN51710.1 - 1e-08 35.2 0.1 2.7e-08 33.8 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN51710.1 - 2.1e-07 31.3 0.1 4.9e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DHOase PF12890.7 RLN51710.1 - 0.018 15.0 0.1 0.042 13.8 0.1 1.6 1 0 0 1 1 1 0 Dihydro-orotase-like Acetyltransf_CG PF14542.6 RLN51710.1 - 0.032 14.3 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 RLN51710.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 RLN51710.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Asn_synthase PF00733.21 RLN51711.1 - 8.5e-19 68.4 1.6 1e-06 28.6 0.0 3.2 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 RLN51711.1 - 9.4e-08 32.0 0.0 4.1e-07 29.9 0.0 2.1 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 RLN51711.1 - 0.00017 21.8 0.0 0.00053 20.2 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain Methyltransf_11 PF08241.12 RLN51718.1 - 2.4e-08 34.5 0.0 5.2e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN51718.1 - 6.1e-08 33.3 0.0 1.4e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN51718.1 - 0.00066 19.6 0.0 0.00094 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN51718.1 - 0.00067 19.5 0.0 0.00094 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN51718.1 - 0.00077 20.2 0.0 0.0015 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN51718.1 - 0.0016 17.9 0.0 0.0042 16.4 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family AOX PF01786.17 RLN51719.1 - 2.9e-18 66.3 0.0 3.6e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase AOX PF01786.17 RLN51720.1 - 2.4e-18 66.5 0.0 6.2e-18 65.2 0.0 1.7 2 0 0 2 2 2 1 Alternative oxidase AhpC-TSA PF00578.21 RLN51743.1 - 6.1e-46 155.4 0.0 1.2e-24 86.6 0.0 2.2 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 RLN51743.1 - 2.4e-27 95.4 0.1 5.9e-14 52.0 0.0 2.1 2 0 0 2 2 2 2 Redoxin AhpC-TSA_2 PF13911.6 RLN51743.1 - 0.0024 18.0 0.0 0.21 11.7 0.0 2.6 2 1 0 2 2 2 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 RLN51743.1 - 0.0029 17.2 0.0 0.32 10.5 0.0 2.2 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF899) KAR9 PF08580.10 RLN51743.1 - 0.17 10.4 0.3 0.21 10.1 0.3 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 IKI3 PF04762.12 RLN51744.1 - 2.6e-171 571.8 0.0 2.4e-151 505.8 0.0 2.4 1 1 2 3 3 3 2 IKI3 family ANAPC4_WD40 PF12894.7 RLN51744.1 - 0.054 13.8 0.3 1.1 9.5 0.1 3.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_C1 PF00112.23 RLN51745.1 - 6.6e-30 104.8 0.1 7.2e-30 104.7 0.1 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RLN51745.1 - 0.11 11.2 0.2 0.16 10.7 0.2 1.1 1 0 0 1 1 1 0 Peptidase C1-like family Meiosis_expr PF15163.6 RLN51745.1 - 0.15 12.7 0.6 1.1 10.0 0.1 2.3 3 0 0 3 3 3 0 Meiosis-expressed Terminase_1 PF03354.15 RLN51746.1 - 0.15 10.6 0.0 0.17 10.4 0.0 1.0 1 0 0 1 1 1 0 Phage Terminase Bystin PF05291.11 RLN51747.1 - 1.5e-51 175.4 0.0 2.2e-51 174.9 0.0 1.3 1 0 0 1 1 1 1 Bystin Ribosomal_60s PF00428.19 RLN51747.1 - 0.21 12.2 5.0 0.45 11.1 5.0 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein CRAL_TRIO PF00650.20 RLN51748.1 - 2.7e-20 72.7 0.0 5.3e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 RLN51748.1 - 0.0057 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Rho_GDI PF02115.17 RLN51749.1 - 3.5e-29 101.9 0.0 4.6e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Mito_carr PF00153.27 RLN51755.1 - 3.4e-14 52.5 0.3 3.4e-14 52.5 0.3 1.5 2 0 0 2 2 2 1 Mitochondrial carrier protein Piwi PF02171.17 RLN51756.1 - 1.6e-96 323.1 0.0 2.3e-96 322.6 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 RLN51756.1 - 2.2e-23 82.6 0.0 3.8e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 RLN51756.1 - 1.6e-20 74.1 0.0 3.5e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoMid PF16487.5 RLN51756.1 - 1.6e-14 53.9 0.1 4.2e-14 52.6 0.1 1.8 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL1 PF08699.10 RLN51756.1 - 2.1e-13 49.7 0.1 5e-13 48.5 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 RLN51756.1 - 3.7e-13 49.6 0.1 9.9e-13 48.2 0.1 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain Pkinase_Tyr PF07714.17 RLN51757.1 - 4.1e-43 147.5 0.0 8.8e-43 146.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN51757.1 - 1.5e-38 132.7 0.0 4e-38 131.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 RLN51757.1 - 0.095 12.6 0.1 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family SesA PF17107.5 RLN51757.1 - 0.11 12.7 2.9 0.16 12.2 0.1 2.7 3 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases MCU PF04678.13 RLN51757.1 - 1.6 8.8 5.5 0.84 9.7 0.1 2.7 1 1 0 2 2 2 0 Mitochondrial calcium uniporter DDE_3 PF13358.6 RLN51774.1 - 2.7e-11 43.4 0.0 7.4e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HSDR_N PF04313.14 RLN51775.1 - 0.0013 18.7 0.5 0.0046 16.9 0.6 1.9 1 1 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) FadA PF09403.10 RLN51775.1 - 4.1 8.0 8.3 2 8.9 5.9 1.6 2 0 0 2 2 2 0 Adhesion protein FadA DDE_Tnp_1_7 PF13843.6 RLN51790.1 - 1e-15 57.9 0.0 1.3e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 PH PF00169.29 RLN51819.1 - 0.083 13.4 0.0 0.11 13.1 0.0 1.1 1 0 0 1 1 1 0 PH domain P34-Arc PF04045.14 RLN51820.1 - 1.2e-65 221.6 0.0 1.6e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc tRNA_bind PF01588.20 RLN51820.1 - 2.4e-22 78.9 0.1 4.8e-22 77.9 0.1 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain Pep_M12B_propep PF01562.19 RLN51820.1 - 0.11 12.7 0.1 0.64 10.2 0.0 2.0 2 0 0 2 2 2 0 Reprolysin family propeptide 7tm_3 PF00003.22 RLN51852.1 - 6.3e-05 22.8 0.1 7.1e-05 22.7 0.1 1.0 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Colicin_im PF03857.13 RLN51852.1 - 0.059 13.3 0.0 0.08 12.9 0.0 1.2 1 0 0 1 1 1 0 Colicin immunity protein Phage_holin_3_6 PF07332.11 RLN51852.1 - 0.17 11.9 3.5 0.26 11.3 3.5 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2721 PF11026.8 RLN51852.1 - 0.18 11.7 1.9 0.2 11.5 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) LSM PF01423.22 RLN51853.1 - 2.2e-09 36.9 0.1 5.7e-09 35.5 0.1 1.8 1 1 0 1 1 1 1 LSM domain Peptidase_S10 PF00450.22 RLN51854.1 - 1.1e-47 163.4 0.0 1.4e-47 163.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Methyltransf_25 PF13649.6 RLN51855.1 - 1.7e-13 51.1 0.0 5.1e-13 49.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 RLN51855.1 - 6.3e-13 48.6 0.0 8.4e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 RLN51855.1 - 6.4e-13 48.9 0.0 1.1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN51855.1 - 4.4e-12 46.5 0.0 1.1e-11 45.2 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN51855.1 - 1.9e-07 31.8 0.0 4.3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN51855.1 - 8.6e-07 28.9 0.0 2.9e-06 27.2 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN51855.1 - 3.6e-05 23.2 0.0 6.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 RLN51855.1 - 0.00044 19.4 0.0 0.00061 18.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 RLN51855.1 - 0.012 15.6 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 RLN51855.1 - 0.018 14.4 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_3 PF01596.17 RLN51855.1 - 0.028 13.6 0.0 0.12 11.5 0.0 1.8 1 1 0 1 1 1 0 O-methyltransferase Methyltransf_PK PF05891.12 RLN51855.1 - 0.03 13.9 0.0 0.057 12.9 0.0 1.5 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase NPP PF08384.10 RLN51855.1 - 0.05 13.7 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Pro-opiomelanocortin, N-terminal region Methyltransf_8 PF05148.15 RLN51855.1 - 0.13 12.1 0.0 0.77 9.6 0.0 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_15 PF09445.10 RLN51855.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase EF-hand_1 PF00036.32 RLN51856.1 - 1.4e-08 33.7 0.1 0.0024 17.3 0.0 3.5 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 RLN51856.1 - 2.1e-08 33.5 0.0 0.00063 19.5 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain WW PF00397.26 RLN51856.1 - 1.8e-07 31.1 0.7 0.0013 18.8 1.0 2.8 2 0 0 2 2 2 2 WW domain EF-hand_7 PF13499.6 RLN51856.1 - 1.4e-06 28.6 0.2 0.0082 16.6 0.0 3.4 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 RLN51856.1 - 0.0068 15.9 0.2 0.61 9.7 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 RLN51856.1 - 0.016 15.0 0.0 5.2 7.0 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain pair Anoctamin PF04547.12 RLN51859.1 - 1.6e-36 126.1 12.6 1.9e-36 125.9 12.6 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel PUB_1 PF18486.1 RLN51859.1 - 0.067 13.0 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain HSF_DNA-bind PF00447.17 RLN51863.1 - 7.8e-30 103.3 1.5 1.8e-29 102.2 1.5 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Sas10_Utp3 PF04000.15 RLN51863.1 - 9.6e-10 39.0 3.8 2.5e-09 37.6 0.5 2.7 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Pox_F17 PF04767.12 RLN51864.1 - 0.07 13.6 1.0 0.15 12.6 1.0 1.5 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein NOA36 PF06524.12 RLN51866.1 - 0.16 11.3 4.3 0.23 10.7 4.3 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 RLN51866.1 - 0.19 12.1 6.8 0.38 11.2 6.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Lipoxygenase PF00305.19 RLN51876.1 - 3.2e-07 29.2 0.1 4.4e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 Lipoxygenase Oxidored_FMN PF00724.20 RLN51901.1 - 8.1e-84 281.8 0.0 9.2e-84 281.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Cation_efflux PF01545.21 RLN51902.1 - 6.2e-12 45.7 3.1 4.8e-11 42.8 4.2 1.8 1 1 1 2 2 2 1 Cation efflux family ZT_dimer PF16916.5 RLN51902.1 - 4.8e-08 33.0 0.6 8.4e-08 32.2 0.6 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Dynein_light PF01221.18 RLN51904.1 - 7.1e-24 83.9 0.2 8.9e-24 83.6 0.2 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Herpes_UL21 PF03252.13 RLN51904.1 - 0.12 11.1 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL21 ARL2_Bind_BART PF11527.8 RLN51905.1 - 4.2e-10 39.8 0.0 7.9e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Tn7_Tnp_TnsA_C PF08721.11 RLN51905.1 - 0.16 12.7 1.3 1.3 9.7 0.1 2.8 2 1 1 3 3 3 0 TnsA endonuclease C terminal Choline_transpo PF04515.12 RLN51906.1 - 4.3e-39 134.6 15.1 5.3e-38 131.0 12.6 2.3 2 1 0 2 2 2 2 Plasma-membrane choline transporter DUF4059 PF13268.6 RLN51906.1 - 0.64 10.5 5.0 16 6.0 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) Peptidase_C2 PF00648.21 RLN51907.1 - 1.9e-09 37.0 0.0 4.2e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Calpain family cysteine protease EF-hand_7 PF13499.6 RLN51908.1 - 0.044 14.2 2.2 0.4 11.2 0.1 2.9 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 RLN51908.1 - 0.63 10.1 3.0 1.9 8.6 0.1 3.1 4 0 0 4 4 4 0 EF-hand domain ABC2_membrane_3 PF12698.7 RLN51909.1 - 2.5e-42 145.2 18.3 8.5e-27 94.2 4.1 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 RLN51909.1 - 8e-42 143.0 0.0 4e-20 72.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter Ribosomal_S28e PF01200.18 RLN51909.1 - 2.1e-27 94.9 1.7 7e-27 93.2 1.7 1.9 1 0 0 1 1 1 1 Ribosomal protein S28e AAA_21 PF13304.6 RLN51909.1 - 6.8e-13 49.1 0.3 3.2e-06 27.2 0.0 3.4 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN51909.1 - 0.00066 20.1 0.4 1.1 9.7 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 RLN51909.1 - 0.0039 17.1 0.1 0.24 11.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 RLN51909.1 - 0.004 16.6 0.2 6.9 6.0 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain NB-ARC PF00931.22 RLN51909.1 - 0.011 15.0 0.6 0.046 12.9 0.0 2.2 3 0 0 3 3 3 0 NB-ARC domain SbcCD_C PF13558.6 RLN51909.1 - 0.11 12.7 0.0 5.7 7.2 0.0 3.2 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 RLN51909.1 - 0.14 12.4 0.4 9.7 6.4 0.2 2.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 RLN51909.1 - 0.27 11.0 2.6 8.9 6.1 0.1 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain ABC2_membrane PF01061.24 RLN51909.1 - 0.82 9.0 34.5 0.027 13.9 14.4 3.7 3 0 0 3 3 3 0 ABC-2 type transporter AAA PF00004.29 RLN51910.1 - 2.1e-38 131.8 0.0 3.8e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RLN51910.1 - 8.2e-09 35.1 0.1 2.5e-08 33.6 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 RLN51910.1 - 7.7e-06 25.7 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RLN51910.1 - 2.8e-05 24.4 0.2 0.28 11.5 0.0 2.8 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.21 RLN51910.1 - 0.0032 16.9 0.0 0.0074 15.7 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 RLN51910.1 - 0.0033 16.7 0.0 0.0058 15.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 RLN51910.1 - 0.0034 17.4 0.0 0.0064 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 RLN51910.1 - 0.0082 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 RLN51910.1 - 0.011 16.1 0.0 0.029 14.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 RLN51910.1 - 0.018 15.1 0.1 0.063 13.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 RLN51910.1 - 0.019 15.0 0.0 0.055 13.5 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 RLN51910.1 - 0.019 14.5 0.1 0.15 11.6 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 RLN51910.1 - 0.021 15.2 3.7 0.025 15.0 0.1 2.9 2 2 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 RLN51910.1 - 0.022 14.5 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 RLN51910.1 - 0.022 14.7 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_2 PF07724.14 RLN51910.1 - 0.028 14.6 0.0 0.065 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 RLN51910.1 - 0.084 13.0 0.0 0.28 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RLN51910.1 - 0.088 13.3 0.0 0.24 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.10 RLN51910.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA_7 PF12775.7 RLN51910.1 - 0.19 11.3 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Isochorismatase PF00857.20 RLN51911.1 - 6.9e-32 111.0 1.0 1.3e-31 110.2 1.0 1.5 1 0 0 1 1 1 1 Isochorismatase family WD40 PF00400.32 RLN51912.1 - 3.9e-45 150.9 9.5 2e-07 31.6 0.2 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN51912.1 - 1.1e-09 38.4 0.2 0.27 11.5 0.1 4.6 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN51912.1 - 2.6e-05 23.4 0.3 0.00061 18.8 0.1 2.6 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RLN51912.1 - 3.1e-05 22.8 0.1 0.016 13.9 0.1 3.4 3 1 0 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 RLN51912.1 - 0.00011 21.2 0.0 0.0091 14.8 0.0 3.0 2 1 0 3 3 3 1 Nup133 N terminal like PALB2_WD40 PF16756.5 RLN51912.1 - 0.041 12.8 0.0 0.42 9.5 0.0 2.3 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 RLN51912.1 - 0.18 10.1 0.0 0.72 8.1 0.0 1.8 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz bZIP_1 PF00170.21 RLN51913.1 - 1.7e-05 24.8 5.6 2.7e-05 24.2 5.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RLN51913.1 - 0.00025 21.1 6.9 0.00038 20.5 6.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper XPG_I PF00867.18 RLN51914.1 - 3.1e-12 46.7 0.5 9.5e-12 45.1 0.2 2.0 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 RLN51914.1 - 5.1e-12 46.1 0.0 1.2e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 RLN51914.1 - 1.3e-05 24.8 0.0 3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 XPG domain containing DUF4817 PF16087.5 RLN51914.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) Pribosyltran_N PF13793.6 RLN51915.1 - 2.4e-50 169.3 0.2 2.5e-49 166.0 0.2 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 RLN51915.1 - 4.1e-27 95.4 0.3 1.2e-26 93.9 0.3 1.8 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 RLN51915.1 - 7.9e-12 45.0 0.0 2.1e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 RLN51915.1 - 0.016 14.6 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase GATase PF00117.28 RLN51916.1 - 1e-37 129.8 0.3 4e-23 82.2 0.1 2.0 2 0 0 2 2 2 2 Glutamine amidotransferase class-I EST1_DNA_bind PF10373.9 RLN51918.1 - 1.1e-29 103.9 0.0 2.3e-29 102.8 0.0 1.6 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain RNase_Zc3h12a PF11977.8 RLN51918.1 - 2.4e-25 89.1 0.0 4.7e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PRORP PF16953.5 RLN51918.1 - 1.2e-06 28.3 0.0 2.9e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 Protein-only RNase P EST1 PF10374.9 RLN51918.1 - 0.0041 17.8 3.6 0.0051 17.4 0.2 2.7 2 1 0 2 2 2 1 Telomerase activating protein Est1 Molybdop_Fe4S4 PF04879.16 RLN51918.1 - 0.067 13.2 1.3 0.54 10.3 0.3 2.5 2 0 0 2 2 2 0 Molybdopterin oxidoreductase Fe4S4 domain TPR_2 PF07719.17 RLN51918.1 - 0.078 13.1 1.0 0.51 10.6 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN51918.1 - 0.16 11.9 0.1 0.61 10.0 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN51918.1 - 0.3 11.8 3.9 0.71 10.6 1.6 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN51919.1 - 1.5e-10 40.4 0.8 0.089 12.6 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN51919.1 - 2.7e-08 33.3 6.4 0.021 14.9 0.4 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN51919.1 - 2.1e-07 30.5 0.0 0.068 12.9 0.0 4.0 4 0 0 4 4 4 2 TPR repeat TPR_16 PF13432.6 RLN51919.1 - 2.4e-07 31.3 10.1 0.03 15.0 0.5 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 RLN51919.1 - 2.4e-07 31.0 11.5 0.022 15.5 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN51919.1 - 1.7e-05 24.5 4.3 0.15 12.1 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN51919.1 - 3.2e-05 24.1 10.5 0.089 13.1 0.3 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN51919.1 - 0.00027 20.9 0.3 15 6.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 RLN51919.1 - 0.00053 20.2 1.9 0.052 14.0 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN51919.1 - 0.00065 20.2 4.7 0.076 13.5 0.3 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN51919.1 - 0.0016 18.2 8.7 0.32 10.9 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_5 PF12688.7 RLN51919.1 - 0.035 14.3 6.1 0.79 10.0 5.0 2.9 1 1 1 2 2 2 0 Tetratrico peptide repeat TPR_9 PF13371.6 RLN51919.1 - 4.8 7.4 12.9 0.6 10.3 0.9 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat RCC1 PF00415.18 RLN51920.1 - 2e-93 306.8 27.1 3.5e-18 66.0 0.6 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN51920.1 - 2.4e-39 132.3 34.2 3.6e-10 39.4 0.6 8.3 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 RLN51920.1 - 1.2e-25 89.9 0.3 3.4e-25 88.4 0.1 1.8 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 RLN51920.1 - 0.00068 19.7 0.5 0.011 15.8 0.1 2.7 2 1 1 3 3 3 1 BTB And C-terminal Kelch DUF4213 PF13938.6 RLN51920.1 - 0.071 13.3 3.8 10 6.4 0.0 3.9 4 0 0 4 4 4 0 Putative heavy-metal chelation DUF4455 PF14643.6 RLN51921.1 - 5.7e-49 167.0 17.8 2.5e-37 128.6 6.0 3.9 4 0 0 4 4 4 2 Domain of unknown function (DUF4455) DUF4456 PF14644.6 RLN51921.1 - 8.4e-39 133.4 3.0 2.5e-38 131.9 0.3 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4456) RNA_pol_Rbc25 PF08292.12 RLN51921.1 - 1.6e-08 34.9 0.0 5.4e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 RLN51921.1 - 2.5e-08 34.1 0.2 9.6e-08 32.3 0.2 2.1 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Ku_N PF03731.15 RLN51921.1 - 0.035 13.9 0.2 0.099 12.4 0.2 1.7 1 0 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain DUF1751 PF08551.10 RLN51922.1 - 0.021 15.3 0.0 0.025 15.1 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) DUF563 PF04577.14 RLN51983.1 - 2.4e-29 103.0 0.0 4.4e-29 102.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF563) HTH_21 PF13276.6 RLN51983.1 - 0.31 11.2 2.5 4.9 7.4 0.0 2.7 2 1 0 2 2 2 0 HTH-like domain HD PF01966.22 RLN51984.1 - 3.3e-12 46.7 0.1 6.7e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 HD domain FYVE PF01363.21 RLN51986.1 - 7.6e-12 45.2 9.6 1.9e-11 44.0 9.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN51986.1 - 0.041 14.1 10.5 0.097 12.9 10.5 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 RLN51987.1 - 3.3e-11 43.1 14.1 8.4e-11 41.9 14.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger Pkinase PF00069.25 RLN51988.1 - 2.1e-48 165.0 0.0 9.6e-42 143.2 0.0 3.9 2 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN51988.1 - 6.5e-46 156.7 0.0 8.9e-41 139.9 0.0 3.5 2 1 1 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.22 RLN51988.1 - 0.0022 17.6 0.0 0.0055 16.3 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 RLN51988.1 - 0.005 16.2 0.0 0.018 14.3 0.0 1.9 1 1 0 1 1 1 1 Kinase-like DUF5129 PF17173.4 RLN51988.1 - 0.027 13.6 0.9 0.043 12.9 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) Kdo PF06293.14 RLN51988.1 - 0.073 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN51988.1 - 0.086 11.6 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Tugs PF17840.1 RLN51988.1 - 0.086 13.0 0.3 2.2 8.6 0.1 2.8 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain DUF4606 PF15379.6 RLN51988.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) APH PF01636.23 RLN51988.1 - 2.1 8.2 7.2 0.23 11.4 0.1 2.8 4 0 0 4 4 4 0 Phosphotransferase enzyme family CCT PF06203.14 RLN51992.1 - 3.2e-09 36.7 4.3 5.7e-09 35.9 4.3 1.3 1 0 0 1 1 1 1 CCT motif Tankyrase_bdg_C PF15327.6 RLN51992.1 - 0.07 13.6 1.1 18 5.8 2.3 2.8 2 1 1 3 3 3 0 Tankyrase binding protein C terminal domain CCT_2 PF09425.10 RLN51992.1 - 0.084 12.8 3.5 0.17 11.8 3.5 1.4 1 0 0 1 1 1 0 Divergent CCT motif His_Phos_1 PF00300.22 RLN51993.1 - 9.7e-15 54.8 0.3 2.7e-14 53.3 0.3 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MTP18 PF10558.9 RLN51994.1 - 3.2e-20 72.8 1.6 1.1e-17 64.5 1.6 2.9 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Pkinase PF00069.25 RLN51996.1 - 4.3e-30 105.0 0.0 6.3e-30 104.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN51996.1 - 1.4e-07 31.1 0.0 1.8e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF604 PF04646.12 RLN51996.1 - 0.25 10.7 0.0 0.39 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF604 Pkinase PF00069.25 RLN51997.1 - 1.2e-21 77.3 0.0 1.4e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN51997.1 - 2.5e-11 43.4 0.0 2.9e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_3 PF00933.21 RLN52005.1 - 7.1e-53 180.0 0.0 8.9e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN52005.1 - 1.6e-17 64.2 0.0 2.6e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain S-AdoMet_synt_C PF02773.16 RLN52011.1 - 6.5e-65 217.3 0.4 1.2e-64 216.4 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 RLN52011.1 - 1.6e-47 160.6 0.1 3.8e-47 159.5 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 RLN52011.1 - 2e-43 147.1 0.3 2e-43 147.1 0.3 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Thump_like PF18096.1 RLN52011.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 THUMP domain-like Nore1-SARAH PF16517.5 RLN52012.1 - 0.39 10.7 7.2 3.9 7.4 1.0 2.9 3 0 0 3 3 3 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain FAD_binding_3 PF01494.19 RLN52013.1 - 7.6e-05 22.1 1.7 0.00054 19.3 0.1 2.8 4 0 0 4 4 4 1 FAD binding domain Pyr_redox_3 PF13738.6 RLN52013.1 - 0.00039 19.8 0.1 0.0014 18.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 RLN52013.1 - 0.00084 18.7 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RLN52013.1 - 0.0011 18.6 0.1 0.0029 17.3 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 RLN52013.1 - 0.0013 17.5 0.1 0.0021 16.8 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 RLN52013.1 - 0.0024 17.0 0.2 0.0047 16.1 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 RLN52013.1 - 0.0052 16.1 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 RLN52013.1 - 0.013 15.7 0.0 0.11 12.8 0.1 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain SPOR PF05036.13 RLN52013.1 - 0.068 13.6 0.1 0.068 13.6 0.1 3.3 4 0 0 4 4 4 0 Sporulation related domain FAD_oxidored PF12831.7 RLN52013.1 - 0.097 12.0 3.0 0.072 12.4 0.4 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 RLN52013.1 - 0.12 13.0 0.2 0.35 11.5 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HNF-1_N PF04814.13 RLN52013.1 - 3 8.4 9.4 0.54 10.9 2.5 3.0 2 1 1 3 3 3 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Ank_2 PF12796.7 RLN52021.1 - 3e-39 133.5 16.3 2.7e-06 27.9 0.0 10.4 8 5 0 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN52021.1 - 3.4e-31 107.2 16.0 0.00025 21.5 0.4 12.6 10 4 4 14 14 14 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN52021.1 - 9.5e-31 105.5 19.9 1.2e-07 31.9 0.1 11.1 10 2 2 12 12 12 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN52021.1 - 1.2e-23 80.6 17.3 0.0062 16.9 0.0 14.8 17 0 0 17 17 17 6 Ankyrin repeat Ank PF00023.30 RLN52021.1 - 6.5e-20 70.6 32.5 0.011 16.1 0.1 15.0 16 0 0 16 16 16 5 Ankyrin repeat LANC_like PF05147.13 RLN52021.1 - 0.11 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein Ank_4 PF13637.6 RLN52024.1 - 1.5e-22 79.7 5.8 0.00031 21.2 0.3 6.9 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN52024.1 - 1.2e-18 66.9 9.6 1.1 9.7 0.0 10.6 7 4 3 10 10 10 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN52024.1 - 6.2e-18 65.2 0.3 3.2e-05 24.4 0.0 5.6 1 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN52024.1 - 1.4e-09 37.3 0.2 28 5.7 0.0 8.8 8 1 1 9 9 9 1 Ankyrin repeat Ank PF00023.30 RLN52024.1 - 0.01 16.3 0.2 2e+02 2.7 0.1 5.8 6 2 0 6 6 6 0 Ankyrin repeat YrzO PF14142.6 RLN52037.1 - 0.051 13.5 0.6 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 YrzO-like protein MFS_1 PF07690.16 RLN52038.1 - 2.6e-35 122.0 14.9 2.6e-35 122.0 14.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 RLN52038.1 - 0.0036 16.7 3.0 0.0036 16.7 3.0 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 RLN52039.1 - 5.7e-32 111.0 26.0 8.1e-32 110.5 26.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Oxidored_molyb PF00174.19 RLN52040.1 - 5.9e-55 185.5 0.0 9.4e-55 184.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 RLN52040.1 - 1.7e-51 173.9 1.2 2.7e-51 173.2 1.2 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 RLN52040.1 - 4.3e-33 113.6 0.0 1.1e-32 112.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 RLN52040.1 - 2.6e-31 108.5 0.0 8.9e-31 106.8 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 RLN52040.1 - 2.7e-22 78.7 0.0 5.6e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 RLN52040.1 - 0.00034 20.8 0.0 0.0013 18.9 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Pyr_redox_2 PF07992.14 RLN52041.1 - 0.0033 16.7 0.0 0.0036 16.6 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RLN52041.1 - 0.0084 16.6 0.0 0.009 16.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 RLN52041.1 - 0.025 14.8 0.0 0.027 14.7 0.0 1.1 1 0 0 1 1 1 0 TrkA-N domain AA_kinase PF00696.28 RLN52041.1 - 0.037 13.6 0.0 0.038 13.6 0.0 1.1 1 0 0 1 1 1 0 Amino acid kinase family FA_synthesis PF02504.15 RLN52041.1 - 0.059 12.4 0.0 0.059 12.4 0.0 1.0 1 0 0 1 1 1 0 Fatty acid synthesis protein NAD_binding_7 PF13241.6 RLN52041.1 - 0.12 12.8 0.0 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 Putative NAD(P)-binding MAPEG PF01124.18 RLN52051.1 - 1e-15 57.8 0.1 1.8e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 MAPEG family zf-BED PF02892.15 RLN52051.1 - 0.0041 17.1 0.1 0.015 15.3 0.1 2.0 1 0 0 1 1 1 1 BED zinc finger Dimer_Tnp_hAT PF05699.14 RLN52051.1 - 0.0091 15.8 0.1 0.023 14.5 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RNA_pol_Rpb2_6 PF00562.28 RLN52078.1 - 2.4e-123 412.1 0.0 3e-123 411.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 RLN52078.1 - 1.6e-33 114.9 0.5 4.1e-33 113.6 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 RLN52078.1 - 6.1e-22 77.6 0.2 3.9e-21 75.0 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 RLN52078.1 - 5.4e-20 71.5 2.0 1.1e-19 70.4 2.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.14 RLN52078.1 - 5.9e-11 42.3 0.0 1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.17 RLN52078.1 - 2.6e-08 34.3 1.2 7.9e-08 32.8 1.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_1 PF04563.15 RLN52078.1 - 0.00023 20.7 0.0 0.00035 20.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit Tyrosinase PF00264.20 RLN52079.1 - 4.9e-13 49.9 0.4 2.8e-12 47.4 0.1 2.2 2 1 0 2 2 2 1 Common central domain of tyrosinase Tyrosinase PF00264.20 RLN52080.1 - 4.3e-25 89.3 0.2 8.5e-13 49.1 0.0 2.9 2 1 0 2 2 2 2 Common central domain of tyrosinase CLIP PF12032.8 RLN52080.1 - 0.073 13.4 0.6 12 6.2 0.1 2.6 2 0 0 2 2 2 0 Regulatory CLIP domain of proteinases DUF5363 PF17320.2 RLN52080.1 - 8.4 6.3 11.9 0.36 10.7 0.4 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5363) Amidohydro_1 PF01979.20 RLN52081.1 - 2.1e-71 241.0 1.0 2.6e-71 240.7 1.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 RLN52081.1 - 1e-19 71.4 4.2 1.1e-17 64.7 0.2 2.4 2 1 0 2 2 2 2 Amidohydrolase family DAO PF01266.24 RLN52084.1 - 2.8e-36 125.8 1.1 3.6e-36 125.5 1.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 RLN52084.1 - 0.00033 19.9 0.2 0.00099 18.3 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 RLN52084.1 - 0.0018 18.7 0.0 0.039 14.4 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox PF00070.27 RLN52084.1 - 0.0085 16.6 0.6 0.1 13.2 0.4 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RLN52084.1 - 0.03 13.6 0.4 0.16 11.2 1.0 1.8 2 0 0 2 2 2 0 FAD binding domain Glu_dehyd_C PF16912.5 RLN52084.1 - 0.047 13.2 0.0 10 5.5 0.1 2.3 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 RLN52084.1 - 0.15 11.3 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pterin_bind PF00809.22 RLN52085.1 - 3.8e-87 292.0 0.2 8.1e-87 290.9 0.2 1.6 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 RLN52085.1 - 3.7e-11 43.5 0.1 3.7e-11 43.5 0.1 3.5 3 1 1 4 4 4 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) HPPK PF01288.20 RLN52086.1 - 5.8e-18 65.4 0.0 6.6e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Bromodomain PF00439.25 RLN52087.1 - 1.6e-15 56.9 0.0 3e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain DUF4887 PF16228.5 RLN52087.1 - 1.5e-05 25.2 5.5 1.5e-05 25.2 5.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4887) AAA_23 PF13476.6 RLN52087.1 - 0.015 15.8 6.9 0.65 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Vfa1 PF08432.10 RLN52087.1 - 0.065 13.6 0.6 0.065 13.6 0.6 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.6 RLN52087.1 - 0.2 11.3 0.0 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 FAM176 family DUF1840 PF08895.11 RLN52087.1 - 0.32 11.4 9.4 0.46 10.8 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Med19 PF10278.9 RLN52087.1 - 0.45 10.4 33.6 1.3 8.9 13.3 3.1 3 0 0 3 3 3 0 Mediator of RNA pol II transcription subunit 19 Folate_carrier PF01770.18 RLN52087.1 - 0.55 8.9 0.0 0.55 8.9 0.0 1.5 2 0 0 2 2 2 0 Reduced folate carrier UPF0239 PF06783.11 RLN52087.1 - 1.2 9.4 15.5 0.2 11.9 2.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) EIIBC-GUT_N PF03612.14 RLN52087.1 - 1.6 8.5 5.9 0.6 9.8 0.2 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2956 PF11169.8 RLN52087.1 - 2 8.7 17.6 0.7 10.1 4.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Connexin PF00029.19 RLN52087.1 - 2.4 7.9 6.2 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Connexin Mitoc_mL59 PF18126.1 RLN52087.1 - 2.5 8.4 16.3 0.21 11.9 4.9 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein mL59 RNA_polI_A34 PF08208.11 RLN52087.1 - 2.8 8.0 24.7 0.45 10.6 9.1 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 DHHC PF01529.20 RLN52088.1 - 4.5e-28 98.0 15.0 4.5e-28 98.0 15.0 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.6 RLN52088.1 - 0.087 12.7 1.9 0.13 12.2 0.2 2.0 2 0 0 2 2 2 0 Transglutaminase-like superfamily DUF3040 PF11239.8 RLN52088.1 - 3 8.2 8.1 21 5.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) FSA_C PF10479.9 RLN52089.1 - 0.11 10.6 0.1 0.15 10.2 0.1 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Sec7 PF01369.20 RLN52090.1 - 7.7e-63 211.5 0.4 1.5e-62 210.6 0.1 1.7 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 RLN52090.1 - 3.9e-31 108.1 2.9 3.9e-31 108.1 2.9 3.8 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 RLN52090.1 - 3.9e-06 26.7 0.6 1.4e-05 24.9 0.6 1.9 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 RLN52090.1 - 0.14 12.0 0.3 6.9 6.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) Epiglycanin_TR PF05647.11 RLN52091.1 - 0.35 10.8 5.3 0.6 10.1 5.3 1.3 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like RabGAP-TBC PF00566.18 RLN52092.1 - 2.8e-39 135.0 0.1 4.3e-39 134.4 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Elicitin PF00964.17 RLN52093.1 - 1.9e-14 53.5 1.9 4.3e-14 52.4 1.9 1.7 1 0 0 1 1 1 1 Elicitin DUF743 PF05332.11 RLN52093.1 - 0.0084 16.2 0.6 0.044 13.8 0.6 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF743) ERM PF00769.19 RLN52093.1 - 0.069 13.0 37.5 0.048 13.5 16.9 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family NAD_binding_10 PF13460.6 RLN52094.1 - 6e-09 36.1 0.3 8.2e-09 35.6 0.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 RLN52094.1 - 0.00014 22.3 0.0 0.00025 21.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 RLN52094.1 - 0.00084 19.0 0.1 0.00094 18.8 0.1 1.3 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 RLN52094.1 - 0.00098 18.6 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 RLN52094.1 - 0.0016 17.7 0.0 0.087 12.0 0.0 2.2 1 1 0 2 2 2 1 Male sterility protein KR PF08659.10 RLN52094.1 - 0.0097 15.8 0.0 0.014 15.3 0.0 1.4 1 1 0 1 1 1 1 KR domain Acetyltransf_1 PF00583.25 RLN52147.1 - 1.5e-12 47.7 0.0 2.2e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RLN52147.1 - 1e-05 25.5 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN52147.1 - 1.6e-05 24.8 0.0 3.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 RLN52147.1 - 0.00067 20.0 0.0 0.0012 19.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 RLN52147.1 - 0.01 15.9 0.2 0.029 14.4 0.1 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 RLN52147.1 - 0.074 13.2 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UPF0029 PF01205.19 RLN52148.1 - 3.8e-07 30.4 0.0 8.1e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 LMBR1 PF04791.16 RLN52149.1 - 9.7e-23 80.8 22.6 7.7e-17 61.4 14.6 2.0 1 1 0 2 2 2 2 LMBR1-like membrane protein Inhibitor_I53 PF11714.8 RLN52149.1 - 0.23 11.7 0.2 0.69 10.1 0.0 1.9 2 0 0 2 2 2 0 Thrombin inhibitor Madanin FYVE PF01363.21 RLN52153.1 - 4e-09 36.5 11.4 7.4e-09 35.6 11.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN52153.1 - 0.027 14.7 6.6 0.063 13.5 6.6 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Pkinase_Tyr PF07714.17 RLN52160.1 - 1.9e-44 151.9 0.0 3.3e-44 151.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN52160.1 - 2.5e-38 131.9 0.0 4.5e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.23 RLN52160.1 - 1.3e-25 88.6 1.6 0.00077 19.4 0.0 8.6 8 0 0 8 8 8 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN52160.1 - 1.6e-09 38.0 18.0 0.025 15.1 0.1 6.6 6 0 0 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 RLN52160.1 - 1.6e-06 28.4 31.6 0.024 15.0 2.3 6.1 3 2 5 8 8 8 7 HEAT repeats HEAT PF02985.22 RLN52160.1 - 2.5e-06 27.2 8.2 10 6.7 0.0 7.5 8 0 0 8 8 7 1 HEAT repeat SelB-wing_1 PF09105.10 RLN52160.1 - 0.0091 15.9 1.6 0.15 12.1 0.1 3.3 2 1 0 2 2 2 1 Elongation factor SelB, winged helix Atx10homo_assoc PF09759.9 RLN52160.1 - 0.01 15.9 0.0 1.3 9.1 0.0 3.9 3 2 2 5 5 5 0 Spinocerebellar ataxia type 10 protein domain MoaE PF02391.17 RLN52160.1 - 0.066 13.5 0.1 14 6.0 0.0 3.6 5 0 0 5 5 5 0 MoaE protein Kinase-like PF14531.6 RLN52160.1 - 0.1 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF4476 PF14771.6 RLN52160.1 - 0.1 12.9 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) Aminotran_3 PF00202.21 RLN52164.1 - 7.3e-07 28.2 0.0 8.4e-07 28.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Ribosomal_60s PF00428.19 RLN52165.1 - 2 9.0 10.0 0.13 12.8 3.0 2.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein SOAR PF16533.5 RLN52168.1 - 0.11 12.4 5.1 0.26 11.3 5.1 1.5 1 0 0 1 1 1 0 STIM1 Orai1-activating region BCIP PF13862.6 RLN52169.1 - 1.3e-48 165.6 0.0 2.1e-48 164.9 0.0 1.3 1 0 0 1 1 1 1 p21-C-terminal region-binding protein SEO_C PF14577.6 RLN52169.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Sieve element occlusion C-terminus FYDLN_acid PF09538.10 RLN52169.1 - 2.4 8.9 10.6 5.1 7.8 10.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) SQS_PSY PF00494.19 RLN52170.1 - 3.5e-47 161.1 7.4 4.1e-47 160.9 7.4 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase MORN PF02493.20 RLN52171.1 - 1.7e-65 213.2 97.7 4.3e-07 29.4 0.7 17.8 19 0 0 19 19 19 16 MORN repeat Vps8 PF12816.7 RLN52172.1 - 1e-58 198.1 0.0 6.2e-57 192.3 0.0 2.8 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 RLN52172.1 - 4.3e-12 46.1 2.2 0.00021 21.2 0.0 3.5 3 0 0 3 3 3 3 Region in Clathrin and VPS Chromo PF00385.24 RLN52172.1 - 4.9e-07 29.6 0.0 9.7e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain WD40 PF00400.32 RLN52172.1 - 0.0028 18.5 0.1 0.022 15.6 0.1 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN52172.1 - 0.017 15.4 0.0 0.056 13.7 0.0 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.8 RLN52172.1 - 0.086 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region Dehydrin PF00257.19 RLN52172.1 - 0.12 13.0 0.1 0.12 13.0 0.1 4.7 5 1 0 5 5 5 0 Dehydrin Spt46 PF17734.1 RLN52172.1 - 0.25 11.1 0.0 0.25 11.1 0.0 2.6 3 0 0 3 3 3 0 Spermatogenesis-associated protein 46 UPF0565 PF10561.9 RLN52172.1 - 3.6 6.7 7.3 0.44 9.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 PRKCSH-like PF12999.7 RLN52174.1 - 9.2e-24 84.2 9.6 1.5e-23 83.5 8.4 1.9 1 1 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 RLN52174.1 - 1e-12 48.0 0.1 1.9e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 RLN52174.1 - 0.01 16.1 4.2 0.01 16.1 4.2 2.6 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A MscS_porin PF12795.7 RLN52174.1 - 0.011 15.4 7.2 0.018 14.6 7.2 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain MutS_III PF05192.18 RLN52174.1 - 0.067 13.4 0.0 0.098 12.9 0.0 1.3 1 0 0 1 1 1 0 MutS domain III ATG27 PF09451.10 RLN52174.1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF2968 PF11180.8 RLN52174.1 - 0.5 10.0 8.0 0.74 9.4 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Yuri_gagarin PF15934.5 RLN52174.1 - 0.91 9.3 4.5 3.9 7.2 4.5 1.8 1 1 1 2 2 2 0 Yuri gagarin AdenylateSensor PF16579.5 RLN52179.1 - 0.095 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Adenylate sensor of SNF1-like protein kinase SnoaL_4 PF13577.6 RLN52180.1 - 2.7e-10 40.5 0.1 4.1e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 RLN52180.1 - 0.00071 20.2 0.1 0.0014 19.2 0.1 1.5 1 1 0 1 1 1 1 SnoaL-like domain IBN_N PF03810.19 RLN52181.1 - 5.6e-09 35.8 1.5 3.2e-08 33.4 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 RLN52181.1 - 9.7e-09 34.5 1.0 1.9e-07 30.3 0.1 2.3 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.12 RLN52181.1 - 9.3e-07 29.0 5.6 0.00039 20.5 0.0 3.7 4 0 0 4 4 4 2 Exportin 1-like protein Importin_rep_4 PF18808.1 RLN52181.1 - 0.00033 20.9 2.3 0.0049 17.1 0.0 3.4 4 0 0 4 4 4 1 Importin repeat HEAT_EZ PF13513.6 RLN52181.1 - 0.15 12.6 22.2 0.098 13.2 0.7 6.7 8 0 0 8 8 8 0 HEAT-like repeat HEAT PF02985.22 RLN52181.1 - 0.18 12.1 4.3 7.7 7.1 0.0 5.7 7 0 0 7 7 7 0 HEAT repeat Sulfate_transp PF00916.20 RLN52182.1 - 1.4e-39 135.9 11.0 2e-39 135.5 11.0 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 RLN52182.1 - 8.8e-14 51.3 0.0 1.6e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 RLN52182.1 - 2.7e-06 27.0 0.0 8.1e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 STAS domain Hydrolase PF00702.26 RLN52183.1 - 1.2e-12 48.6 0.2 5.5e-12 46.4 0.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 RLN52183.1 - 0.0028 17.4 0.7 0.0045 16.8 0.2 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN52183.1 - 0.0098 16.0 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) PH PF00169.29 RLN52228.1 - 7.9e-13 48.8 0.0 1.7e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN52228.1 - 0.096 13.0 0.0 0.32 11.3 0.0 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 RLN52228.1 - 0.67 10.4 6.3 0.098 13.1 0.5 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain ATAD4 PF15321.6 RLN52228.1 - 8.5 7.8 8.2 5.6 8.4 1.6 3.3 2 1 0 2 2 2 0 ATPase family AAA domain containing 4 TFCD_C PF12612.8 RLN52229.1 - 4.3e-52 176.7 0.1 3.3e-50 170.6 0.0 2.9 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal TPR_10 PF13374.6 RLN52229.1 - 4.4e-07 29.6 5.8 9.6e-07 28.5 0.7 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN52229.1 - 9.8e-07 29.0 4.5 1.9e-06 28.1 0.6 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat HEAT PF02985.22 RLN52229.1 - 1.2e-06 28.2 18.3 0.2 12.0 0.0 8.2 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.6 RLN52229.1 - 2.9e-05 24.4 15.6 0.49 10.8 0.2 6.3 6 1 0 6 6 5 3 HEAT repeats HEAT_EZ PF13513.6 RLN52229.1 - 0.00032 21.1 25.8 0.18 12.3 1.2 8.4 7 2 1 8 8 8 2 HEAT-like repeat TPR_16 PF13432.6 RLN52229.1 - 0.0012 19.4 1.1 0.0075 16.9 1.1 2.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN52229.1 - 0.0023 18.6 4.9 0.16 12.9 0.6 4.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN52229.1 - 0.017 14.9 0.4 0.31 10.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Cnd3 PF12719.7 RLN52229.1 - 0.076 12.2 0.5 5.9 6.0 0.0 3.1 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain TPR_11 PF13414.6 RLN52229.1 - 0.083 12.6 0.1 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 TPR repeat HEAT_PBS PF03130.16 RLN52229.1 - 0.1 13.4 9.4 27 5.8 0.0 6.1 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat TPR_7 PF13176.6 RLN52229.1 - 0.11 12.6 4.7 0.49 10.5 0.2 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN52229.1 - 0.14 12.7 3.0 1.2 9.7 2.0 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN52229.1 - 0.18 12.0 0.1 0.18 12.0 0.1 3.1 4 0 0 4 4 3 0 Tetratricopeptide repeat zf-MYND PF01753.18 RLN52229.1 - 0.72 10.0 5.6 1.7 8.8 5.6 1.6 1 0 0 1 1 1 0 MYND finger SF-assemblin PF06705.11 RLN52230.1 - 1.6e-36 125.9 23.5 1.7e-28 99.6 17.3 2.0 1 1 1 2 2 2 2 SF-assemblin/beta giardin DUF3584 PF12128.8 RLN52230.1 - 1.1e-05 23.2 18.3 1.3e-05 23.0 18.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF5098 PF17023.5 RLN52230.1 - 0.00019 20.5 1.8 0.00019 20.5 1.8 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF5098) Prominin PF05478.11 RLN52230.1 - 0.063 11.2 4.9 0.09 10.7 4.9 1.2 1 0 0 1 1 1 0 Prominin RNase_3_N PF18497.1 RLN52230.1 - 0.18 12.0 4.3 10 6.4 0.9 2.9 2 1 1 3 3 3 0 Ribonuclease III N-terminal domain PIN_2 PF10130.9 RLN52230.1 - 0.38 11.0 3.5 0.42 10.9 0.1 2.4 2 1 1 3 3 3 0 PIN domain Fungal_TACC PF12709.7 RLN52230.1 - 0.56 10.7 0.1 0.56 10.7 0.1 3.4 3 1 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Fzo_mitofusin PF04799.13 RLN52230.1 - 0.73 9.4 7.0 0.33 10.5 1.7 2.6 1 1 1 2 2 2 0 fzo-like conserved region Prp31_C PF09785.9 RLN52230.1 - 0.76 10.7 5.7 0.69 10.9 4.0 1.9 1 1 0 1 1 1 0 Prp31 C terminal domain Baculo_PEP_C PF04513.12 RLN52230.1 - 1.2 9.1 6.5 2.2 8.3 4.4 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 RLN52230.1 - 1.4 9.4 8.4 1.1 9.8 1.0 4.0 4 1 0 4 4 3 0 Nucleopolyhedrovirus P10 protein Nup54 PF13874.6 RLN52230.1 - 9.4 6.3 19.5 0.33 11.0 10.5 2.8 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 FWWh PF14922.6 RLN52231.1 - 3.1e-18 66.1 0.1 6.1e-18 65.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function Mg_trans_NIPA PF05653.14 RLN52232.1 - 5.6e-20 71.6 12.6 8e-20 71.1 12.6 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA PLDc_2 PF13091.6 RLN52232.1 - 1.4e-10 41.2 0.0 0.00012 21.9 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 RLN52232.1 - 0.00038 20.5 0.1 0.66 10.3 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif EamA PF00892.20 RLN52232.1 - 0.014 15.6 7.9 0.014 15.6 7.9 3.8 2 2 0 4 4 4 0 EamA-like transporter family eIF3_subunit PF08597.10 RLN52232.1 - 0.049 13.6 0.2 0.08 12.8 0.2 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit MatE PF01554.18 RLN52233.1 - 2.9e-37 127.8 28.4 7e-21 74.6 11.0 2.2 2 0 0 2 2 2 2 MatE PsbM PF05151.12 RLN52233.1 - 0.0079 16.0 0.2 0.029 14.2 0.2 2.0 1 0 0 1 1 1 1 Photosystem II reaction centre M protein (PsbM) DUF2304 PF10066.9 RLN52233.1 - 1.5 9.1 6.0 0.92 9.8 0.1 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2304) RIO1 PF01163.22 RLN52234.1 - 3.1e-30 105.2 0.0 3.1e-30 105.2 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 RLN52234.1 - 0.0013 17.6 0.1 0.0013 17.6 0.1 2.2 1 1 0 2 2 2 1 Fungal protein kinase RNA_pol_3_Rpc31 PF11705.8 RLN52234.1 - 0.0023 18.3 10.9 0.0023 18.3 10.9 2.2 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 RLN52234.1 - 0.03 12.5 24.3 0.043 12.0 24.3 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RLN52234.1 - 0.045 13.2 26.3 0.063 12.7 26.3 1.2 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 RLN52234.1 - 0.047 13.8 34.4 0.082 13.0 34.4 1.4 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 RLN52234.1 - 0.073 11.4 22.6 0.091 11.0 22.6 1.1 1 0 0 1 1 1 0 CDC45-like protein APH PF01636.23 RLN52234.1 - 0.18 11.7 3.1 0.75 9.7 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Nop53 PF07767.11 RLN52234.1 - 0.35 10.2 31.0 0.63 9.4 31.0 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SURF2 PF05477.11 RLN52234.1 - 0.72 9.5 17.7 1.1 8.9 17.7 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF5398 PF17376.2 RLN52235.1 - 0.081 13.6 1.4 0.081 13.6 1.4 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5398) NPV_P10 PF05531.12 RLN52235.1 - 0.29 11.6 2.3 1.7 9.2 1.9 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CDC45 PF02724.14 RLN52235.1 - 7.3 4.8 19.3 11 4.2 19.3 1.4 1 1 0 1 1 1 0 CDC45-like protein DUF572 PF04502.13 RLN52239.1 - 0.037 13.6 1.6 0.073 12.7 1.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_C1 PF00112.23 RLN52240.1 - 7e-55 186.5 13.4 7e-55 186.5 13.4 2.2 2 0 0 2 2 2 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RLN52240.1 - 0.00031 19.7 1.2 0.021 13.6 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family FAA_hydrolase PF01557.18 RLN52241.1 - 2.4e-56 190.9 0.0 3.1e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 RLN52241.1 - 0.029 15.3 0.1 0.054 14.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2437) Myotub-related PF06602.14 RLN52242.1 - 3.7e-120 401.1 0.0 5e-120 400.6 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 RLN52242.1 - 0.0012 18.9 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 RLN52242.1 - 0.02 14.7 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RLN52242.1 - 0.026 14.1 0.0 0.058 12.9 0.0 1.5 2 0 0 2 2 2 0 Protein-tyrosine phosphatase BBL5 PF07289.11 RLN52242.1 - 0.2 10.7 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein DUF4203 PF13886.6 RLN52261.1 - 1.6e-39 135.7 23.7 2.4e-39 135.1 23.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) CytB6-F_Fe-S PF08802.10 RLN52261.1 - 0.37 10.9 2.5 1.5 8.9 2.5 2.1 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit Kinesin PF00225.23 RLN52262.1 - 2.6e-25 89.0 0.0 2.8e-11 42.9 0.0 3.2 3 1 1 4 4 4 2 Kinesin motor domain DUF4472 PF14739.6 RLN52262.1 - 6.1e-22 78.4 12.9 6.1e-22 78.4 12.9 7.0 4 1 4 8 8 8 1 Domain of unknown function (DUF4472) Microtub_bd PF16796.5 RLN52262.1 - 3e-05 24.0 0.0 0.0034 17.3 0.0 2.8 2 0 0 2 2 2 1 Microtubule binding HALZ PF02183.18 RLN52262.1 - 0.31 11.3 27.3 0.83 9.9 0.4 7.3 6 1 0 6 6 6 0 Homeobox associated leucine zipper HAD PF12710.7 RLN52263.1 - 4.5e-09 37.0 0.0 6.3e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RLN52263.1 - 0.049 13.9 0.0 0.1 12.9 0.0 1.6 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 RLN52263.1 - 0.064 13.0 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Fe-ADH PF00465.19 RLN52264.1 - 6.7e-39 133.7 3.9 2e-23 82.8 1.0 2.1 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 RLN52264.1 - 5.2e-05 23.1 0.4 0.00017 21.4 0.0 1.9 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Ank_4 PF13637.6 RLN52268.1 - 3.7e-34 116.6 17.0 9.3e-07 29.3 0.2 11.1 10 2 0 10 10 10 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN52268.1 - 3.6e-29 101.2 4.5 3.7e-07 30.6 0.1 6.8 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN52268.1 - 1.1e-24 86.1 20.5 0.019 15.3 0.1 13.4 6 3 7 13 13 13 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN52268.1 - 1.5e-21 74.2 6.3 1.4 9.7 0.0 14.4 15 0 0 15 15 15 3 Ankyrin repeat Ank PF00023.30 RLN52268.1 - 0.0016 18.8 5.3 1.2e+02 3.3 0.0 7.9 8 1 0 8 8 8 0 Ankyrin repeat Cas9_Topo PF17894.1 RLN52268.1 - 0.081 13.0 0.3 7.7 6.7 0.0 3.7 4 0 0 4 4 4 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 Gp_dh_N PF00044.24 RLN52282.1 - 6e-39 132.5 0.0 8.1e-39 132.0 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 RLN52282.1 - 0.032 14.3 0.1 0.1 12.8 0.1 1.9 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Gp_dh_N PF00044.24 RLN52283.1 - 2e-26 92.3 0.1 3.6e-26 91.4 0.0 1.4 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 RLN52283.1 - 0.066 12.6 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.20 RLN52283.1 - 0.075 13.2 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sugar_tr PF00083.24 RLN52318.1 - 2.9e-21 75.9 8.9 3.3e-21 75.7 8.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN52318.1 - 0.0038 16.2 1.5 0.0038 16.2 1.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily VGLL4 PF15245.6 RLN52344.1 - 0.18 11.9 3.8 0.19 11.8 3.8 1.1 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 Ly49 PF08391.10 RLN52344.1 - 1.3 9.4 4.7 0.99 9.8 3.5 1.4 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region MRP-S33 PF08293.11 RLN52345.1 - 1.5e-09 38.0 1.0 4.5e-09 36.4 1.0 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Ribul_P_3_epim PF00834.19 RLN52346.1 - 2.2e-68 229.5 0.0 2.6e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PG_binding_3 PF09374.10 RLN52346.1 - 0.077 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Predicted Peptidoglycan domain QRPTase_C PF01729.19 RLN52346.1 - 0.13 12.0 0.0 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain JmjN PF02375.17 RLN52346.1 - 0.16 12.0 0.0 0.47 10.5 0.0 1.8 1 0 0 1 1 1 0 jmjN domain TMP-TENI PF02581.17 RLN52346.1 - 0.21 10.9 1.2 3 7.1 0.2 2.9 2 1 1 3 3 3 0 Thiamine monophosphate synthase RL10P_insert PF17777.1 RLN52347.1 - 6.3e-21 74.2 0.0 1e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 RLN52347.1 - 2.2e-19 69.4 0.2 3.1e-19 69.0 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 F-actin_cap_A PF01267.17 RLN52347.1 - 0.052 13.0 0.3 0.076 12.4 0.3 1.2 1 0 0 1 1 1 0 F-actin capping protein alpha subunit Epiglycanin_C PF14654.6 RLN52348.1 - 0.022 14.8 0.2 0.042 13.9 0.2 1.5 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Caskin1-CID PF16600.5 RLN52348.1 - 0.26 11.9 5.8 5.3 7.7 3.6 2.6 2 0 0 2 2 2 0 Caskin1 CASK-interaction domain EzrA PF06160.12 RLN52349.1 - 0.0019 16.5 0.2 0.0025 16.1 0.2 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA APG6_N PF17675.1 RLN52349.1 - 0.027 15.0 3.8 0.12 12.9 0.7 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4315 PF14193.6 RLN52349.1 - 0.51 10.4 3.1 0.6 10.2 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4315) Seryl_tRNA_N PF02403.22 RLN52349.1 - 0.63 10.3 6.8 0.81 9.9 0.8 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FUSC PF04632.12 RLN52349.1 - 0.86 8.1 4.6 1.5 7.3 3.9 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF1993 PF09351.10 RLN52349.1 - 1.2 9.3 4.8 0.99 9.5 2.2 2.0 1 1 2 3 3 3 0 Domain of unknown function (DUF1993) Oleosin PF01277.17 RLN52350.1 - 0.0058 16.4 3.3 0.012 15.4 3.3 1.4 1 0 0 1 1 1 1 Oleosin DUF3827 PF12877.7 RLN52350.1 - 0.88 7.9 3.0 1.2 7.4 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF997 PF06196.12 RLN52350.1 - 3.9 7.6 5.9 2.9 8.0 4.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF997) Acetyltransf_1 PF00583.25 RLN52351.1 - 7.2e-15 55.3 0.0 9.3e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RLN52351.1 - 2.4e-13 50.3 0.0 3.6e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RLN52351.1 - 6.4e-12 45.5 0.0 9.4e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 RLN52351.1 - 4.7e-06 26.7 0.0 1.7e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN52351.1 - 3.6e-05 23.7 0.0 5.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 RLN52351.1 - 0.011 15.8 0.0 0.013 15.7 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 RLN52351.1 - 0.031 14.4 0.0 0.068 13.3 0.0 1.6 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase GNAT_acetyltr_2 PF13718.6 RLN52351.1 - 0.054 12.9 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase 2 MOZ_SAS PF01853.18 RLN52351.1 - 0.082 12.6 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family HrpB7 PF09486.10 RLN52352.1 - 0.003 18.0 2.2 0.003 18.0 2.2 3.3 3 0 0 3 3 3 1 Bacterial type III secretion protein (HrpB7) Paramyx_P_V_C PF03210.13 RLN52352.1 - 0.0084 15.9 0.5 0.037 13.8 0.3 2.1 2 0 0 2 2 2 1 Paramyxovirus P/V phosphoprotein C-terminal JAB PF01398.21 RLN52353.1 - 4.9e-12 45.9 0.0 1.2e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease FLYWCH PF04500.16 RLN52355.1 - 0.00042 20.4 0.2 0.0012 18.9 0.0 1.8 2 0 0 2 2 2 1 FLYWCH zinc finger domain rve PF00665.26 RLN52356.1 - 9.4e-06 25.8 0.0 1.1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain JmjC PF02373.22 RLN52363.1 - 3.9e-16 59.5 0.1 8.3e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 RLN52363.1 - 2.7e-10 40.8 0.0 5.2e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 RLN52363.1 - 4e-08 33.0 10.9 8.5e-08 32.0 10.9 1.6 1 0 0 1 1 1 1 PHD-finger DMPK_coil PF08826.10 RLN52364.1 - 0.00042 20.4 0.3 0.00088 19.3 0.3 1.5 1 0 0 1 1 1 1 DMPK coiled coil domain like SHE3 PF17078.5 RLN52364.1 - 0.013 15.2 1.1 0.016 15.0 1.1 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 ABC2_membrane PF01061.24 RLN52371.1 - 1.8e-29 102.7 28.2 3e-29 102.0 28.2 1.4 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN52371.1 - 0.002 18.0 0.2 0.002 18.0 0.2 2.4 3 0 0 3 3 3 1 CDR ABC transporter AAA_21 PF13304.6 RLN52371.1 - 0.028 14.2 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 RLN52372.1 - 1e-66 224.4 69.1 4.9e-36 124.1 24.9 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN52372.1 - 5.4e-33 114.4 0.0 2.3e-15 57.3 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 RLN52372.1 - 3e-07 30.3 2.5 0.0001 22.1 0.0 3.2 2 0 0 2 2 2 1 CDR ABC transporter AAA_21 PF13304.6 RLN52372.1 - 1e-06 28.8 0.0 0.17 11.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN52372.1 - 2.4e-06 27.6 1.2 0.011 15.6 0.2 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 RLN52372.1 - 2.4e-05 24.0 0.0 0.056 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 RLN52372.1 - 3e-05 24.5 0.1 0.33 11.3 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 RLN52372.1 - 3.6e-05 23.4 6.1 0.015 15.0 1.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 RLN52372.1 - 0.00028 20.1 52.9 0.0053 15.9 17.8 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_22 PF13401.6 RLN52372.1 - 0.00056 20.2 0.4 0.67 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 RLN52372.1 - 0.00097 18.6 3.0 0.6 9.5 0.2 3.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 RLN52372.1 - 0.0018 17.6 1.3 0.24 10.7 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin AAA_30 PF13604.6 RLN52372.1 - 0.0034 17.1 0.9 1.3 8.7 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 RLN52372.1 - 0.0042 17.3 0.1 4.1 7.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 RLN52372.1 - 0.0045 17.5 0.4 0.28 11.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 RLN52372.1 - 0.0048 17.0 1.4 0.79 9.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 RLN52372.1 - 0.0081 16.7 0.1 7.4 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 RLN52372.1 - 0.018 15.5 0.8 6.5 7.2 0.3 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 RLN52372.1 - 0.033 13.9 0.9 7.8 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RLN52372.1 - 0.058 13.8 0.7 6 7.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase G-alpha PF00503.20 RLN52372.1 - 0.089 11.9 0.0 0.41 9.7 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit PRK PF00485.18 RLN52372.1 - 0.1 12.3 0.2 10 5.8 0.1 2.7 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Ploopntkinase3 PF18751.1 RLN52372.1 - 0.11 12.4 0.5 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF87 PF01935.17 RLN52372.1 - 0.12 12.4 5.2 0.94 9.5 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain NACHT PF05729.12 RLN52372.1 - 0.15 11.9 4.3 9.6 6.1 1.1 2.7 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 RLN52372.1 - 0.18 11.4 2.0 1.4 8.4 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 RLN52372.1 - 0.19 11.7 0.8 5.1 7.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Roc PF08477.13 RLN52372.1 - 0.21 11.8 1.1 17 5.7 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 RLN52372.1 - 0.22 11.3 0.6 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 RLN52372.1 - 0.34 10.9 3.3 1.1 9.3 0.2 2.8 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 RLN52372.1 - 0.64 9.3 1.9 9.3 5.5 0.1 2.4 2 0 0 2 2 2 0 KaiC DUF2681 PF10883.8 RLN52377.1 - 0.0031 17.9 1.3 0.0043 17.4 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) Protocadherin PF08374.11 RLN52377.1 - 0.0068 16.4 0.1 0.0077 16.2 0.1 1.1 1 0 0 1 1 1 1 Protocadherin EphA2_TM PF14575.6 RLN52377.1 - 0.0099 16.7 0.1 0.016 16.1 0.1 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF2615 PF11027.8 RLN52377.1 - 0.026 14.7 0.0 0.036 14.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) DUF5385 PF17359.2 RLN52377.1 - 0.032 13.8 2.4 0.048 13.2 1.4 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5385) Shisa PF13908.6 RLN52377.1 - 0.082 13.1 0.0 0.09 13.0 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator LapA_dom PF06305.11 RLN52377.1 - 0.094 12.5 0.4 0.15 11.9 0.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain FixQ PF05545.11 RLN52377.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ TMEM132D_C PF15706.5 RLN52377.1 - 0.16 11.8 1.3 0.45 10.3 0.8 1.9 1 1 1 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term SET PF00856.28 RLN52378.1 - 7.7e-22 78.5 0.0 3e-21 76.5 0.0 2.0 1 1 0 1 1 1 1 SET domain WD40 PF00400.32 RLN52379.1 - 8.2e-25 86.6 11.7 3e-05 24.7 0.0 9.7 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN52379.1 - 4.3e-06 26.9 0.1 0.33 11.3 0.0 4.5 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN52379.1 - 0.0025 16.9 0.2 0.017 14.1 0.0 2.4 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Arm PF00514.23 RLN52400.1 - 1.7e-08 34.2 0.7 0.0025 17.8 0.0 3.8 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN52400.1 - 0.0011 19.3 2.9 0.069 13.5 0.2 2.6 1 1 2 3 3 3 3 HEAT repeats Atx10homo_assoc PF09759.9 RLN52400.1 - 0.037 14.0 0.2 2.3 8.3 0.1 2.7 2 1 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Peptidase_S15 PF02129.18 RLN52405.1 - 3.1e-33 115.5 1.0 8e-33 114.2 1.0 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 RLN52405.1 - 2e-17 63.9 0.2 3.7e-17 63.0 0.2 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 RLN52405.1 - 7.5e-05 22.1 0.2 0.00012 21.4 0.2 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Isochorismatase PF00857.20 RLN52406.1 - 3.1e-06 27.5 0.0 0.00018 21.8 0.0 2.7 1 1 0 1 1 1 1 Isochorismatase family AAA_25 PF13481.6 RLN52406.1 - 0.02 14.5 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain FG-GAP PF01839.23 RLN52458.1 - 0.018 15.2 0.8 0.05 13.7 0.8 1.8 1 0 0 1 1 1 0 FG-GAP repeat zf-HC5HC2H_2 PF13832.6 RLN52459.1 - 2.6e-21 75.8 1.1 2.6e-21 75.8 1.1 3.0 3 0 0 3 3 3 1 PHD-zinc-finger like domain ResIII PF04851.15 RLN52459.1 - 9.2e-19 68.1 0.0 1.8e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RLN52459.1 - 3.6e-18 65.9 0.1 7.5e-18 64.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-HC5HC2H PF13771.6 RLN52459.1 - 6e-16 58.5 6.1 4.9e-15 55.6 0.0 3.3 3 0 0 3 3 3 1 PHD-like zinc-binding domain DEAD PF00270.29 RLN52459.1 - 5.5e-15 55.6 0.0 1.7e-14 54.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD PF00628.29 RLN52459.1 - 6.4e-11 42.0 26.0 9.3e-10 38.3 5.2 4.4 4 0 0 4 4 4 2 PHD-finger PHD_2 PF13831.6 RLN52459.1 - 7e-11 41.5 2.8 7e-11 41.5 2.8 3.4 3 0 0 3 3 3 2 PHD-finger zf-RanBP PF00641.18 RLN52459.1 - 5.4e-06 25.6 1.4 5.4e-06 25.6 1.4 2.4 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-PHD-like PF15446.6 RLN52459.1 - 0.0019 17.8 0.5 0.0019 17.8 0.5 2.1 2 0 0 2 2 1 1 PHD/FYVE-zinc-finger like domain SWI2_SNF2 PF18766.1 RLN52459.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Prok-RING_1 PF14446.6 RLN52459.1 - 1.2 9.1 13.7 0.03 14.3 3.8 2.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FYVE_2 PF02318.16 RLN52459.1 - 3.2 8.0 6.5 0.46 10.7 0.9 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger ELMO_CED12 PF04727.13 RLN52460.1 - 2.1e-21 76.8 0.0 3e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family DIX PF00778.17 RLN52460.1 - 0.00028 20.7 0.0 0.00066 19.5 0.0 1.6 2 0 0 2 2 2 1 DIX domain APC_N_CC PF16689.5 RLN52461.1 - 0.043 13.9 2.0 0.043 13.9 2.0 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain DUF3585 PF12130.8 RLN52461.1 - 0.055 13.6 6.4 0.092 12.9 6.4 1.4 1 0 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain CPP1-like PF11833.8 RLN52461.1 - 0.78 9.4 4.1 1.3 8.6 4.1 1.4 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Arrestin_N PF00339.29 RLN52462.1 - 2.1e-07 31.1 0.0 4.5e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 RLN52462.1 - 5.8e-06 26.8 0.0 0.019 15.4 0.0 3.0 3 1 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain DUF737 PF05300.11 RLN52463.1 - 0.45 10.9 8.0 0.61 10.4 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Aminotran_1_2 PF00155.21 RLN52464.1 - 2.1e-52 178.5 0.0 3.4e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 RLN52464.1 - 0.0056 15.7 0.0 0.14 11.1 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 RLN52464.1 - 0.036 12.6 0.0 0.17 10.4 0.0 1.9 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.7 RLN52464.1 - 0.14 10.9 0.0 0.51 9.0 0.0 1.8 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase PLDc PF00614.22 RLN52465.1 - 0.00048 20.2 0.1 0.0015 18.6 0.1 1.9 1 0 0 1 1 1 1 Phospholipase D Active site motif PLDc_2 PF13091.6 RLN52465.1 - 0.01 15.7 0.1 1.9 8.4 0.0 2.6 2 0 0 2 2 2 0 PLD-like domain CoA_trans PF01144.23 RLN52466.1 - 2.4e-69 233.1 0.7 1.4e-39 135.8 0.3 2.4 2 1 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 RLN52466.1 - 0.0056 16.6 0.1 0.0094 15.9 0.1 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Phage_int_SAM_2 PF12834.7 RLN52466.1 - 0.088 13.5 0.0 0.19 12.5 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal Pribosyltran PF00156.27 RLN52467.1 - 1.7e-08 34.1 0.0 2.2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 RLN52467.1 - 0.0003 20.3 0.0 0.00039 19.9 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 RLN52467.1 - 0.053 13.0 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Cellulase PF00150.18 RLN52498.1 - 1.1e-30 107.1 0.5 1.4e-30 106.7 0.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.25 RLN52499.1 - 8.2e-63 212.2 0.0 1.1e-62 211.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN52499.1 - 1.4e-28 99.9 0.0 2.2e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 RLN52499.1 - 2.1e-07 31.2 0.8 6.4e-06 26.4 0.1 2.7 3 0 0 3 3 3 1 Regulator of G protein signaling domain Kinase-like PF14531.6 RLN52499.1 - 1.1e-05 24.9 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RLN52499.1 - 0.02 13.9 0.1 0.033 13.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 RLN52499.1 - 0.096 12.0 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family cNMP_binding PF00027.29 RLN52501.1 - 0.019 15.0 0.0 0.044 13.9 0.0 1.7 1 1 0 1 1 1 0 Cyclic nucleotide-binding domain RCC1_2 PF13540.6 RLN52502.1 - 7.8e-06 25.6 19.5 0.0019 18.0 2.1 4.1 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat FAD_binding_2 PF00890.24 RLN52503.1 - 8.1e-75 252.5 2.5 1.1e-74 252.1 2.5 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 RLN52503.1 - 1.7e-08 34.1 1.2 0.00048 19.4 0.8 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RLN52503.1 - 2.1e-05 24.3 1.2 3.4e-05 23.6 1.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 RLN52503.1 - 5.5e-05 22.4 3.5 0.0078 15.3 0.5 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 RLN52503.1 - 0.0039 17.4 0.1 0.011 16.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Succ_DH_flav_C PF02910.20 RLN52503.1 - 0.0077 16.2 0.1 0.021 14.8 0.1 1.7 1 1 0 1 1 1 1 Fumarate reductase flavoprotein C-term FAD_binding_3 PF01494.19 RLN52503.1 - 0.026 13.8 0.1 0.042 13.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 RLN52503.1 - 0.054 12.7 1.5 6.1 6.0 0.1 3.1 2 1 0 3 3 3 0 Thi4 family ApbA PF02558.16 RLN52503.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 RLN52503.1 - 0.2 10.6 0.5 0.32 10.0 0.5 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 RLN52503.1 - 0.6 8.7 2.6 4.8 5.8 0.3 2.7 3 0 0 3 3 3 0 HI0933-like protein FAD_oxidored PF12831.7 RLN52503.1 - 1.1 8.5 5.5 18 4.5 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Peptidase_S8 PF00082.22 RLN52504.1 - 3.4e-40 138.2 2.9 4.7e-40 137.7 1.4 1.9 1 1 1 2 2 2 1 Subtilase family Rap_GAP PF02145.15 RLN52513.1 - 1.9e-55 187.3 0.0 3.2e-55 186.6 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP RGS PF00615.19 RLN52513.1 - 0.0014 18.9 0.0 0.0043 17.3 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain FAM110_C PF14160.6 RLN52513.1 - 0.21 12.6 2.4 0.26 12.4 0.1 2.2 2 0 0 2 2 2 0 Centrosome-associated C terminus EF-hand_6 PF13405.6 RLN52514.1 - 6.4e-08 31.9 0.6 0.0019 18.0 0.0 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RLN52514.1 - 1e-05 25.9 0.1 9.6e-05 22.8 0.0 2.8 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN52514.1 - 0.00012 21.4 0.2 0.61 9.8 0.1 3.0 2 0 0 2 2 2 2 EF hand TMF_DNA_bd PF12329.8 RLN52514.1 - 0.041 13.9 5.9 0.2 11.6 5.9 2.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding EF-hand_8 PF13833.6 RLN52514.1 - 0.087 12.7 0.3 1.1 9.1 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain pair Ig_mannosidase PF17753.1 RLN52524.1 - 1.4e-11 44.0 0.3 3.5e-11 42.7 0.3 1.6 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 RLN52524.1 - 5.3e-07 30.3 0.0 1e-06 29.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 RLN52524.1 - 5.5e-06 26.4 0.1 3.4e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 RLN52524.1 - 0.056 13.9 0.1 0.52 10.8 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function(DUF4981) PX PF00787.24 RLN52525.1 - 4.3e-10 39.6 0.0 7.5e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 PX domain FliX PF10768.9 RLN52525.1 - 0.059 13.9 1.6 0.16 12.5 0.1 2.4 2 0 0 2 2 2 0 Class II flagellar assembly regulator Adaptin_N PF01602.20 RLN52535.1 - 6e-101 338.6 0.8 1.9e-100 336.9 0.8 1.7 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 RLN52535.1 - 3.6e-44 150.6 5.1 3.1e-42 144.3 0.1 3.2 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 RLN52535.1 - 1.7e-20 73.2 0.0 6.5e-20 71.3 0.0 2.1 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 RLN52535.1 - 4.9e-10 39.7 5.4 0.099 13.0 0.0 6.6 4 3 3 7 7 7 3 HEAT repeats HEAT PF02985.22 RLN52535.1 - 3.9e-07 29.8 6.0 5.3 7.6 0.0 6.2 6 0 0 6 6 5 2 HEAT repeat Arm_2 PF04826.13 RLN52535.1 - 0.00028 20.4 0.7 0.0015 18.0 0.2 2.3 1 1 1 2 2 2 1 Armadillo-like Na_Ca_ex_C PF16494.5 RLN52535.1 - 0.013 15.9 0.4 0.059 13.8 0.1 2.1 2 0 0 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain DUF4756 PF15948.5 RLN52535.1 - 0.027 14.3 0.1 0.06 13.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4756) SPO22 PF08631.10 RLN52535.1 - 0.047 13.2 0.5 4 6.9 0.0 3.3 3 1 0 4 4 4 0 Meiosis protein SPO22/ZIP4 like PTPRCAP PF15713.5 RLN52535.1 - 0.055 13.7 0.3 0.11 12.8 0.3 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Arm PF00514.23 RLN52535.1 - 0.1 12.7 0.2 0.61 10.2 0.0 2.5 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat RVT_1 PF00078.27 RLN52554.1 - 2.5e-10 40.2 0.0 5.4e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2959 PF11172.8 RLN52554.1 - 0.29 11.3 2.7 0.46 10.6 1.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) Cauli_VI PF01693.16 RLN52560.1 - 1.9e-12 47.3 0.4 4e-12 46.2 0.1 1.7 2 0 0 2 2 2 1 Caulimovirus viroplasmin RNase_H PF00075.24 RLN52560.1 - 1.2e-06 28.8 0.0 1.9e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 RNase H Pirin PF02678.16 RLN52561.1 - 2.4e-24 85.4 0.4 7.3e-24 83.8 0.0 2.0 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 RLN52561.1 - 1.1e-17 64.2 0.0 3.6e-17 62.6 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin_C_2 PF17954.1 RLN52561.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain ADIP PF11559.8 RLN52572.1 - 0.00075 19.6 25.1 0.00095 19.3 15.7 2.3 1 1 0 2 2 2 1 Afadin- and alpha -actinin-Binding Thioesterase PF00975.20 RLN52572.1 - 0.0021 18.2 2.8 0.0027 17.9 2.8 1.4 1 0 0 1 1 1 1 Thioesterase domain TT_ORF2 PF02957.15 RLN52572.1 - 0.037 14.9 1.6 0.07 14.1 1.6 1.5 1 0 0 1 1 1 0 TT viral ORF2 DUF4806 PF16064.5 RLN52572.1 - 0.17 12.2 2.7 0.8 10.0 1.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4806) SRP_SPB PF02978.19 RLN52572.1 - 0.6 10.8 6.2 12 6.6 6.2 2.7 1 1 0 1 1 1 0 Signal peptide binding domain Exonuc_VII_L PF02601.15 RLN52572.1 - 0.77 9.3 15.2 1.1 8.7 15.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit CtIP_N PF10482.9 RLN52572.1 - 1.6 8.8 20.3 6.6 6.8 15.5 2.8 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF1664 PF07889.12 RLN52572.1 - 1.6 8.8 14.0 0.51 10.4 5.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Enkurin PF13864.6 RLN52572.1 - 1.7 9.1 20.4 0.19 12.2 4.7 2.5 1 1 0 2 2 2 0 Calmodulin-binding DUF4407 PF14362.6 RLN52572.1 - 7.7 5.8 19.2 2.6e+02 0.8 19.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ank_2 PF12796.7 RLN52573.1 - 3.3e-52 175.0 13.5 2.3e-10 40.9 0.0 6.0 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN52573.1 - 8.1e-36 121.6 21.2 0.003 17.8 0.1 12.8 2 2 11 13 13 13 11 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN52573.1 - 1.3e-33 114.9 16.7 5.8e-06 26.8 0.0 9.6 6 3 3 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN52573.1 - 1.8e-23 80.0 4.2 1.7 9.5 0.0 12.5 12 0 0 12 12 12 4 Ankyrin repeat Ank PF00023.30 RLN52573.1 - 2.6e-07 30.8 2.5 15 6.2 0.0 8.5 4 3 5 9 9 9 1 Ankyrin repeat DUF5049 PF16468.5 RLN52573.1 - 1.6e-05 24.7 0.0 25 4.9 0.0 6.4 7 1 1 8 8 8 1 Domain of unknown function (DUF5049) DUF1843 PF08898.10 RLN52573.1 - 0.091 13.3 7.9 5.3 7.6 0.0 6.0 7 0 0 7 7 7 0 Domain of unknown function (DUF1843) IstB_IS21 PF01695.17 RLN52626.1 - 0.023 14.4 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 RLN52626.1 - 0.038 13.6 0.0 0.086 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain U-box PF04564.15 RLN52633.1 - 7.5e-26 90.1 0.0 1.7e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 RLN52633.1 - 1.1e-12 47.2 2.2 0.00086 19.0 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN52633.1 - 2.2e-09 36.7 3.2 0.034 14.2 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat zf-NOSIP PF15906.5 RLN52633.1 - 0.00023 21.2 0.7 0.00047 20.2 0.0 2.0 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein TPR_11 PF13414.6 RLN52633.1 - 0.007 16.0 0.4 0.2 11.4 0.0 3.1 3 0 0 3 3 3 1 TPR repeat TPR_12 PF13424.6 RLN52633.1 - 0.06 13.7 2.7 17 5.8 0.0 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 RLN52633.1 - 0.13 12.6 1.5 20 5.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN52633.1 - 0.17 12.5 2.7 12 6.6 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN52633.1 - 1.1 9.5 5.0 1.4 9.2 2.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RLN52633.1 - 3.1 8.8 5.9 5.3 8.1 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat RCC1 PF00415.18 RLN52635.1 - 1e-72 240.6 16.8 1e-14 54.8 0.1 8.6 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN52635.1 - 3.7e-42 141.3 26.4 4.9e-10 38.9 0.2 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RabGAP-TBC PF00566.18 RLN52635.1 - 1e-40 139.7 0.0 1.8e-40 138.9 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PX PF00787.24 RLN52635.1 - 2.1e-06 27.7 0.0 4.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 PX domain Hira PF07569.11 RLN52635.1 - 0.077 12.7 0.0 75 2.9 0.0 3.7 3 0 0 3 3 3 0 TUP1-like enhancer of split TFIIA PF03153.13 RLN52635.1 - 0.42 10.6 12.0 0.67 9.9 12.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 RLN52635.1 - 7.2 4.7 13.9 12 4.0 13.9 1.2 1 0 0 1 1 1 0 Nop14-like family Amnionless PF14828.6 RLN52636.1 - 0.02 13.7 0.3 0.03 13.2 0.3 1.1 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 RLN52636.1 - 0.38 11.7 0.1 0.38 11.7 0.1 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Cnd3 PF12719.7 RLN52638.1 - 3.6e-40 138.0 2.6 3.6e-40 138.0 2.6 2.2 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 RLN52638.1 - 2.2e-05 24.7 11.7 0.04 14.3 1.1 4.6 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.22 RLN52638.1 - 0.00069 19.7 13.6 0.57 10.6 0.0 7.1 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 RLN52638.1 - 0.046 14.2 5.1 12 6.5 0.0 5.0 5 0 0 5 5 5 0 HEAT-like repeat Hepar_II_III PF07940.13 RLN52638.1 - 0.059 13.0 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Heparinase II/III-like protein Abhydrolase_2 PF02230.16 RLN52656.1 - 1.6e-13 51.0 0.0 2.4e-09 37.3 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.13 RLN52656.1 - 4.7e-05 23.1 0.0 8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 RLN52656.1 - 5.8e-05 22.5 0.1 0.08 12.2 0.1 2.8 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN52656.1 - 0.051 13.2 0.2 1.1 8.8 0.1 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.20 RLN52656.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain MCM PF00493.23 RLN52657.1 - 1.9e-93 311.7 0.0 1.8e-82 275.8 0.0 2.2 2 0 0 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 RLN52657.1 - 1.5e-37 128.2 0.1 3.3e-37 127.2 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RLN52657.1 - 5.4e-27 94.0 1.8 1.8e-26 92.4 1.8 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 RLN52657.1 - 4.3e-10 40.1 0.4 1.4e-09 38.5 0.1 2.1 2 0 0 2 2 1 1 MCM N-terminal domain AAA_5 PF07728.14 RLN52657.1 - 7.5e-08 32.5 0.0 1.9e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 RLN52657.1 - 1.4e-06 27.9 0.1 0.00014 21.3 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 RLN52657.1 - 0.00073 19.3 0.0 0.0089 15.7 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 RLN52657.1 - 0.0014 18.5 0.0 0.0042 16.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DDE_Tnp_2 PF04693.12 RLN52657.1 - 0.0078 15.5 0.1 0.021 14.0 0.0 1.6 2 0 0 2 2 2 1 Archaeal putative transposase ISC1217 Mg_chelatase_C PF13335.6 RLN52657.1 - 0.023 15.3 6.7 0.032 14.8 1.9 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal zf-HC5HC2H PF13771.6 RLN52657.1 - 0.061 13.6 0.3 0.14 12.5 0.3 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain AAA_22 PF13401.6 RLN52657.1 - 0.26 11.6 3.4 5.4 7.3 0.3 3.1 3 1 1 4 4 4 0 AAA domain zf-CHY PF05495.12 RLN52657.1 - 0.62 10.6 2.6 1.3 9.5 2.6 1.5 1 0 0 1 1 1 0 CHY zinc finger Ecl1 PF12855.7 RLN52657.1 - 3.1 8.9 22.2 0.59 11.3 9.6 2.5 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins FAM220 PF15487.6 RLN52657.1 - 6 6.4 5.3 14 5.2 0.1 2.4 2 0 0 2 2 2 0 FAM220 family DUF3325 PF11804.8 RLN52659.1 - 0.0032 17.6 1.1 0.0098 16.0 1.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3325) HA PF03457.14 RLN52660.1 - 8.9e-19 67.6 2.0 0.0031 17.8 0.0 4.8 5 1 0 5 5 5 4 Helicase associated domain VPS28 PF03997.12 RLN52661.1 - 5.4e-59 199.1 0.1 6.7e-59 198.7 0.1 1.1 1 0 0 1 1 1 1 VPS28 protein JIP_LZII PF16471.5 RLN52662.1 - 0.013 15.6 1.7 0.04 14.1 0.3 2.4 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II NIF PF03031.18 RLN52663.1 - 2.8e-23 82.4 0.4 9.1e-15 54.8 0.1 2.3 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase XAP5 PF04921.14 RLN52663.1 - 7.4e-05 22.7 2.5 0.00012 22.0 2.5 1.4 1 0 0 1 1 1 1 XAP5, circadian clock regulator Apt1 PF10351.9 RLN52663.1 - 0.048 12.5 6.2 0.056 12.3 6.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ndc1_Nup PF09531.10 RLN52663.1 - 0.075 11.7 4.6 0.089 11.5 4.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAPA-1 PF04795.12 RLN52663.1 - 0.18 12.6 4.9 0.44 11.4 0.2 2.6 2 0 0 2 2 2 0 PAPA-1-like conserved region Pro_isomerase PF00160.21 RLN52664.1 - 8e-50 169.2 0.1 1.4e-49 168.4 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MOSC PF03473.17 RLN52664.1 - 2.3e-28 98.8 0.0 4.3e-27 94.7 0.0 2.7 3 0 0 3 3 3 1 MOSC domain Aminotran_5 PF00266.19 RLN52664.1 - 1.2e-27 96.8 0.1 5.7e-15 55.1 0.0 3.1 3 0 0 3 3 3 3 Aminotransferase class-V MOSC_N PF03476.16 RLN52664.1 - 1.3e-14 54.1 0.0 1.5e-13 50.7 0.0 2.3 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain N_formyltrans_C PF18216.1 RLN52664.1 - 0.058 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain SNF2_N PF00176.23 RLN52665.1 - 1.4e-14 53.6 0.0 4.2e-14 52.0 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN52665.1 - 4.4e-09 36.7 0.1 2.9e-08 34.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN52665.1 - 0.00017 21.7 0.0 0.00031 20.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit 2-oxoacid_dh PF00198.23 RLN52666.1 - 1.3e-66 224.4 0.1 1.7e-66 224.0 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 RLN52666.1 - 7.8e-31 105.7 7.4 5.4e-16 58.2 0.4 2.6 2 0 0 2 2 2 2 Biotin-requiring enzyme HlyD_3 PF13437.6 RLN52666.1 - 5.8e-06 27.0 7.9 0.017 15.8 0.3 3.7 2 1 1 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 RLN52666.1 - 8e-05 22.4 3.6 0.00064 19.5 0.3 3.0 2 1 1 3 3 3 1 Biotin-lipoyl like GCV_H PF01597.19 RLN52666.1 - 0.00056 19.8 2.2 0.29 11.0 0.3 2.6 2 1 0 2 2 2 2 Glycine cleavage H-protein RnfC_N PF13375.6 RLN52666.1 - 0.079 12.9 1.0 8.1 6.5 0.1 3.1 2 1 0 2 2 2 0 RnfC Barrel sandwich hybrid domain RPA_C PF08784.11 RLN52666.1 - 0.49 11.1 2.1 6 7.6 0.1 3.1 2 1 1 3 3 3 0 Replication protein A C terminal TPR_1 PF00515.28 RLN52667.1 - 0.024 14.5 0.1 0.055 13.3 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Bromodomain PF00439.25 RLN52671.1 - 5.6e-20 71.2 0.1 3.3e-19 68.7 0.0 2.0 2 0 0 2 2 2 1 Bromodomain BET PF17035.5 RLN52671.1 - 2.4e-10 40.4 0.0 4.8e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation cNMP_binding PF00027.29 RLN52673.1 - 3.6e-15 55.8 0.1 4.1e-08 33.2 0.0 3.2 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain PX PF00787.24 RLN52674.1 - 2.2e-05 24.4 0.1 4.4e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 PX domain GMC_oxred_N PF00732.19 RLN52679.1 - 3.7e-97 325.3 0.0 5.2e-97 324.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 RLN52679.1 - 1.1e-36 126.6 0.1 1.9e-36 125.7 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 RLN52679.1 - 2.8e-06 26.7 0.1 0.045 12.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 RLN52679.1 - 5.5e-05 22.4 0.1 8.2e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 RLN52679.1 - 0.00057 19.2 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RLN52679.1 - 0.00065 19.4 0.0 0.011 15.3 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RLN52679.1 - 0.00093 19.4 0.0 0.0027 17.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 RLN52679.1 - 0.0018 17.6 0.1 0.0092 15.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 RLN52679.1 - 0.0063 15.8 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family ApbA PF02558.16 RLN52679.1 - 0.049 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 RLN52679.1 - 0.094 13.0 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 RLN52679.1 - 0.12 11.0 0.0 0.23 10.1 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Abhydrolase_3 PF07859.13 RLN52681.1 - 1.9e-16 60.6 0.0 2.3e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 RLN52681.1 - 0.013 15.1 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Say1_Mug180 PF10340.9 RLN52682.1 - 0.074 11.9 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase DUF2633 PF11119.8 RLN52682.1 - 0.8 9.7 3.8 0.54 10.2 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) DFP PF04127.15 RLN52686.1 - 7.6e-18 65.0 0.0 2.2e-12 47.2 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein BolA PF01722.18 RLN52687.1 - 2.7e-32 110.9 0.7 3.4e-32 110.6 0.7 1.1 1 0 0 1 1 1 1 BolA-like protein Clat_adaptor_s PF01217.20 RLN52688.1 - 5.2e-49 165.8 2.3 2.4e-48 163.7 2.3 1.7 1 1 0 1 1 1 1 Clathrin adaptor complex small chain DUF1644 PF07800.12 RLN52689.1 - 0.028 14.5 8.6 0.057 13.5 8.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) Presenilin PF01080.17 RLN52689.1 - 1.3 7.7 9.9 1.8 7.3 9.9 1.2 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 RLN52689.1 - 1.4 8.2 22.3 1.1 8.6 17.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ALMT PF11744.8 RLN52689.1 - 1.7 7.4 8.9 2.2 7.0 8.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3523 PF12037.8 RLN52689.1 - 3 7.1 35.9 5.1 6.4 35.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Histidinol_dh PF00815.20 RLN52689.1 - 6.7 5.6 8.3 11 4.9 8.3 1.4 1 0 0 1 1 1 0 Histidinol dehydrogenase Nup88 PF10168.9 RLN52689.1 - 9.9 3.8 20.0 14 3.3 20.0 1.1 1 0 0 1 1 1 0 Nuclear pore component HTH_OrfB_IS605 PF12323.8 RLN52690.1 - 4.7e-11 42.0 1.8 1.5e-10 40.4 1.8 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain OrfB_Zn_ribbon PF07282.11 RLN52690.1 - 4.7e-11 42.5 0.6 4.7e-11 42.5 0.6 2.3 2 0 0 2 2 2 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 RLN52690.1 - 0.00091 19.4 0.2 0.00091 19.4 0.2 2.7 3 0 0 3 3 3 1 Probable transposase Filamin PF00630.19 RLN52690.1 - 0.058 14.2 0.0 0.12 13.2 0.0 1.6 1 0 0 1 1 1 0 Filamin/ABP280 repeat Copine PF07002.16 RLN52691.1 - 4.4e-51 173.4 0.6 1e-50 172.2 0.0 1.9 2 0 0 2 2 2 1 Copine Ion_trans_2 PF07885.16 RLN52691.1 - 5e-27 93.7 36.7 2.4e-16 59.4 12.8 3.5 4 0 0 4 4 4 2 Ion channel C2 PF00168.30 RLN52691.1 - 2.1e-21 76.1 0.0 1.4e-12 47.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain Ion_trans PF00520.31 RLN52691.1 - 1.1e-08 34.6 4.3 0.0007 18.9 0.4 2.6 2 0 0 2 2 2 2 Ion transport protein EF-hand_5 PF13202.6 RLN52691.1 - 1.6e-06 27.3 2.6 0.036 13.6 0.8 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 RLN52691.1 - 1.8e-05 25.1 1.8 0.058 13.9 0.9 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN52691.1 - 2.9e-05 23.3 1.2 0.25 11.0 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RLN52691.1 - 3.9e-05 23.3 1.0 0.084 12.9 0.2 3.6 4 0 0 4 4 3 2 EF-hand domain EF-hand_8 PF13833.6 RLN52691.1 - 0.071 13.0 1.7 0.41 10.5 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair vWA-TerF-like PF10138.9 RLN52691.1 - 0.14 12.3 0.1 0.41 10.7 0.0 1.8 2 0 0 2 2 2 0 vWA found in TerF C terminus SUIM_assoc PF16619.5 RLN52691.1 - 3.2 7.9 7.6 7.2 6.8 7.6 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 PspB PF06667.12 RLN52691.1 - 3.4 7.8 4.4 20 5.3 0.5 2.7 2 0 0 2 2 2 0 Phage shock protein B CTP_transf_like PF01467.26 RLN52692.1 - 1.3e-09 38.4 0.2 6.7e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 Cytidylyltransferase-like Pox_A_type_inc PF04508.12 RLN52692.1 - 0.00073 19.3 0.9 0.0024 17.6 0.9 1.9 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat OrfB_Zn_ribbon PF07282.11 RLN52695.1 - 0.00046 20.0 0.2 0.00087 19.2 0.2 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Rod_cone_degen PF15201.6 RLN52695.1 - 0.24 11.5 1.4 0.67 10.1 1.4 1.7 1 0 0 1 1 1 0 Progressive rod-cone degeneration Senescence_reg PF04520.13 RLN52717.1 - 0.079 13.8 0.5 0.079 13.8 0.5 1.9 1 1 1 2 2 2 0 Senescence regulator DHHC PF01529.20 RLN52718.1 - 0.0042 17.2 0.8 0.0089 16.1 0.8 1.8 1 1 0 1 1 1 1 DHHC palmitoyltransferase RIBIOP_C PF04950.12 RLN52722.1 - 3.4e-88 295.9 0.0 3.4e-88 295.9 0.0 2.4 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 RLN52722.1 - 1.7e-28 98.5 0.2 7.6e-28 96.4 0.0 2.4 2 0 0 2 2 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 RLN52722.1 - 2e-05 24.9 0.0 9.7e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN52722.1 - 0.00012 22.5 0.3 0.00044 20.7 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain AAA PF00004.29 RLN52722.1 - 0.00034 21.1 0.0 0.0011 19.5 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 RLN52722.1 - 0.00093 18.8 0.0 0.11 12.1 0.0 3.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 RLN52722.1 - 0.0031 17.7 0.0 0.0031 17.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 RLN52722.1 - 0.0044 17.6 0.0 0.0044 17.6 0.0 4.0 3 1 1 4 4 4 1 AAA domain MMR_HSR1 PF01926.23 RLN52722.1 - 0.0092 16.1 0.1 0.063 13.4 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 RLN52722.1 - 0.012 15.4 0.1 0.025 14.3 0.1 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.9 RLN52722.1 - 0.017 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 RLN52722.1 - 0.02 15.2 0.0 0.049 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 RLN52722.1 - 0.04 13.9 0.0 0.092 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 RLN52722.1 - 0.047 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 NTPase AAA_25 PF13481.6 RLN52722.1 - 0.052 13.1 0.1 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 RLN52722.1 - 0.056 14.0 0.0 0.056 14.0 0.0 2.8 3 0 0 3 3 2 0 ABC transporter RNA_helicase PF00910.22 RLN52722.1 - 0.056 13.8 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 RLN52722.1 - 0.074 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 RLN52722.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Ufd2P_core PF10408.9 RLN52723.1 - 2.7e-170 568.1 0.3 4.5e-170 567.3 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin elongating factor core U-box PF04564.15 RLN52723.1 - 1.2e-29 102.3 0.3 4.3e-29 100.5 0.3 2.0 1 0 0 1 1 1 1 U-box domain GUCT PF08152.12 RLN52723.1 - 0.056 13.7 0.7 3.1 8.2 0.2 2.6 2 0 0 2 2 2 0 GUCT (NUC152) domain Med9 PF07544.13 RLN52723.1 - 1.4 9.1 4.0 0.59 10.3 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 MAGE_N PF12440.8 RLN52723.1 - 1.5 9.5 8.9 3.8 8.3 8.9 1.6 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal DUF1768 PF08719.11 RLN52724.1 - 2.8e-37 128.5 0.0 6.6e-37 127.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Herpes_UL32 PF06070.11 RLN52724.1 - 0.00028 18.8 0.7 0.00055 17.9 0.7 1.4 1 0 0 1 1 1 1 Herpesvirus large structural phosphoprotein UL32 cNMP_binding PF00027.29 RLN52725.1 - 3.6e-22 78.2 0.2 3.9e-09 36.5 0.1 4.8 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain RGS PF00615.19 RLN52725.1 - 1.9e-10 41.0 0.0 3.9e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain RNA_pol_3_Rpc31 PF11705.8 RLN52727.1 - 0.13 12.5 5.1 0.16 12.2 5.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2996 PF11210.8 RLN52728.1 - 0.11 13.0 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2996) AIRC PF00731.20 RLN52742.1 - 4.6e-64 214.5 0.8 4.6e-64 214.5 0.8 2.1 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 RLN52742.1 - 5.4e-30 104.2 0.0 8.7e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 RLN52742.1 - 3.5e-19 68.2 0.0 7.5e-19 67.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 RLN52742.1 - 0.00026 20.6 0.0 0.00053 19.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Tmemb_161AB PF10268.9 RLN52743.1 - 2.6e-40 138.5 5.2 5.3e-39 134.2 5.2 2.3 1 1 0 1 1 1 1 Predicted transmembrane protein 161AB DUF4203 PF13886.6 RLN52744.1 - 6.2e-44 150.1 37.0 7.6e-44 149.8 37.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Trp_oprn_chp PF09534.10 RLN52744.1 - 0.24 11.2 7.7 0.36 10.6 0.0 2.8 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4271 PF14093.6 RLN52744.1 - 5.4 6.9 13.6 5.8 6.8 0.1 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF4271) DUF4203 PF13886.6 RLN52745.1 - 5.8e-81 271.0 71.0 1.4e-43 149.0 31.7 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4203) DUF308 PF03729.13 RLN52745.1 - 0.02 15.2 0.4 0.02 15.2 0.4 7.1 4 2 3 7 7 7 0 Short repeat of unknown function (DUF308) DUF4203 PF13886.6 RLN52746.1 - 3.2e-29 102.0 8.5 3.6e-29 101.9 8.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF4131 PF13567.6 RLN52746.1 - 0.0075 15.9 5.6 0.36 10.5 0.6 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4131) Trp_oprn_chp PF09534.10 RLN52746.1 - 0.015 15.1 0.4 0.029 14.2 0.0 1.7 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ninjurin PF04923.12 RLN52746.1 - 0.041 13.8 0.2 0.11 12.5 0.2 1.6 2 0 0 2 2 2 0 Ninjurin DUF4381 PF14316.6 RLN52746.1 - 0.48 10.7 2.0 1.8 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF2157 PF09925.9 RLN52746.1 - 0.6 9.9 5.0 0.97 9.2 2.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF3180 PF11377.8 RLN52746.1 - 1.6 8.8 6.5 0.5 10.5 1.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3180) DUF1275 PF06912.11 RLN52746.1 - 3.9 7.3 9.3 87 2.9 9.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1275) DUF4203 PF13886.6 RLN52747.1 - 8.6e-44 149.6 30.3 8.6e-44 149.6 30.3 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) Tyrosinase PF00264.20 RLN52748.1 - 3.6e-10 40.5 0.0 3.6e-10 40.5 0.0 4.4 4 1 0 4 4 4 1 Common central domain of tyrosinase DUF4395 PF14340.6 RLN52748.1 - 0.032 14.6 1.4 0.19 12.1 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) DUF3040 PF11239.8 RLN52748.1 - 0.097 13.0 3.5 8.3 6.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Phage_holin_2_4 PF16082.5 RLN52749.1 - 0.0041 16.8 2.5 0.014 15.1 2.5 1.9 1 0 0 1 1 1 1 Bacteriophage holin family, superfamily II-like RIFIN PF02009.16 RLN52749.1 - 0.29 11.0 0.7 0.49 10.2 0.7 1.3 1 0 0 1 1 1 0 Rifin DUF3040 PF11239.8 RLN52749.1 - 0.41 10.9 8.6 3 8.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DUF4395 PF14340.6 RLN52749.1 - 0.6 10.5 7.7 0.074 13.4 0.8 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4395) Fas_alpha_ACP PF18325.1 RLN52755.1 - 7.4e-89 296.2 0.0 5.7e-47 160.1 0.0 2.6 2 0 0 2 2 2 2 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 RLN52755.1 - 2.8e-41 141.4 0.3 5.6e-26 91.4 0.6 2.5 1 1 1 2 2 2 2 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 RLN52755.1 - 4.6e-17 62.4 0.4 1.3e-16 61.0 0.4 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 RLN52755.1 - 3.1e-15 56.2 0.2 1.9e-13 50.5 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 RLN52755.1 - 2.9e-13 50.0 0.0 6.9e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.25 RLN52755.1 - 9.3e-08 31.8 2.5 2.6e-07 30.3 0.0 2.8 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN52755.1 - 3.8e-07 29.9 0.2 1.1e-05 25.1 0.0 2.8 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase NYD-SP12_N PF15015.6 RLN52755.1 - 0.0019 16.6 0.3 0.003 16.0 0.3 1.1 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal GDP_Man_Dehyd PF16363.5 RLN52755.1 - 0.021 14.3 0.1 0.038 13.4 0.1 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase HATPase_c_3 PF13589.6 RLN52756.1 - 0.015 15.1 0.0 3.4 7.5 0.0 2.1 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 2OG-FeII_Oxy_2 PF13532.6 RLN52764.1 - 5.6e-41 140.9 0.0 9.6e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AKAP7_RIRII_bdg PF10470.9 RLN52764.1 - 0.14 12.3 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein bZIP_1 PF00170.21 RLN52764.1 - 0.73 10.0 8.2 2 8.6 8.2 1.8 1 1 0 1 1 1 0 bZIP transcription factor PHD PF00628.29 RLN52765.1 - 2.2e-09 37.1 10.0 4.4e-09 36.1 10.0 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 RLN52765.1 - 0.11 12.1 4.9 0.28 10.8 4.9 1.7 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 RLN52765.1 - 8.9 6.3 14.7 2.7 8.0 8.3 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Inv-AAD PF18785.1 RLN52766.1 - 1.5e-25 89.5 1.5 1.2e-23 83.4 0.8 2.5 2 1 0 2 2 2 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 RLN52766.1 - 4.3e-18 65.0 0.5 6.4e-18 64.5 0.5 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 RLN52766.1 - 6.6e-06 25.9 0.2 1.1e-05 25.2 0.2 1.4 1 1 0 1 1 1 1 MafB19-like deaminase bZIP_1 PF00170.21 RLN52767.1 - 0.039 14.0 6.8 0.072 13.2 6.8 1.4 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 RLN52767.1 - 1.3 9.2 10.0 2.6 8.2 10.0 1.5 1 0 0 1 1 1 0 Basic region leucine zipper PHD PF00628.29 RLN52768.1 - 4.4e-11 42.5 9.9 9.2e-11 41.5 9.9 1.6 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 RLN52768.1 - 0.049 13.2 3.4 0.11 12.2 3.4 1.6 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.6 RLN52768.1 - 0.93 9.8 8.6 2.7 8.3 8.4 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 RLN52768.1 - 1.2 8.8 9.4 0.035 13.7 3.0 1.8 2 0 0 2 2 2 0 PHD-finger MT PF12777.7 RLN52769.1 - 1.3e-14 54.0 0.0 2.1e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor PNP_UDP_1 PF01048.20 RLN52770.1 - 5e-23 81.6 0.1 7.6e-23 81.0 0.1 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily RabGAP-TBC PF00566.18 RLN52772.1 - 6.9e-66 222.0 9.0 3.6e-34 118.3 0.0 2.7 3 0 0 3 3 3 2 Rab-GTPase-TBC domain OxoGdeHyase_C PF16870.5 RLN52772.1 - 0.081 12.6 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase C-terminal DDE_Tnp_ISL3 PF01610.17 RLN52772.1 - 0.095 12.4 3.1 0.26 11.0 0.1 2.3 2 0 0 2 2 2 0 Transposase CRAL_TRIO PF00650.20 RLN52833.1 - 4.5e-18 65.5 0.0 6.4e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain PH PF00169.29 RLN52833.1 - 5.5e-05 23.6 0.0 9.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 PH domain CRAL_TRIO_2 PF13716.6 RLN52833.1 - 0.0039 17.3 0.0 0.0058 16.8 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain ZZ PF00569.17 RLN52847.1 - 2.3e-10 40.1 6.8 5.5e-10 38.9 6.8 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type F-box-like PF12937.7 RLN52847.1 - 8.8e-10 38.3 2.5 3.9e-09 36.3 2.5 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RLN52847.1 - 5.8e-05 22.9 1.1 0.00012 21.8 1.1 1.6 1 0 0 1 1 1 1 F-box domain USP7_ICP0_bdg PF12436.8 RLN52847.1 - 0.049 12.9 0.0 0.33 10.2 0.0 1.9 1 1 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 F-box_4 PF15966.5 RLN52847.1 - 0.35 10.8 1.4 0.56 10.1 0.4 1.8 2 0 0 2 2 2 0 F-box Arm PF00514.23 RLN52876.1 - 4.6e-25 86.8 15.2 3.1e-05 23.9 0.4 7.7 7 0 0 7 7 7 5 Armadillo/beta-catenin-like repeat Pkinase_Tyr PF07714.17 RLN52876.1 - 2.7e-14 53.1 0.0 8.9e-14 51.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RLN52876.1 - 7.7e-12 45.1 0.0 2.7e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain ABC1 PF03109.16 RLN52876.1 - 0.00025 21.2 0.0 0.001 19.2 0.0 2.0 1 0 0 1 1 1 1 ABC1 family HEAT_EZ PF13513.6 RLN52876.1 - 0.0019 18.7 14.6 0.026 15.1 0.1 5.7 4 1 3 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 RLN52876.1 - 0.023 15.1 11.1 1.3 9.4 1.2 4.2 3 1 1 4 4 4 0 HEAT repeats Atx10homo_assoc PF09759.9 RLN52876.1 - 0.23 11.5 12.0 2.2 8.4 0.0 5.2 5 1 0 6 6 6 0 Spinocerebellar ataxia type 10 protein domain eIF3_N PF09440.10 RLN52876.1 - 1.3 9.5 7.5 1.1 9.7 4.4 2.4 3 0 0 3 3 3 0 eIF3 subunit 6 N terminal domain Guanylate_cyc PF00211.20 RLN52929.1 - 8e-11 41.9 0.0 1.2e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain NfeD PF01957.18 RLN52929.1 - 0.14 12.6 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Epimerase_2 PF02350.19 RLN52929.1 - 0.16 10.8 0.0 0.25 10.2 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DUF4296 PF14129.6 RLN52930.1 - 0.0041 17.7 1.4 0.39 11.3 0.2 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4296) Fe-ADH PF00465.19 RLN52930.1 - 0.41 9.4 2.9 0.89 8.3 0.4 2.1 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase Ribosomal_S5 PF00333.20 RLN52932.1 - 3.7e-29 100.5 1.2 8e-29 99.4 1.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 RLN52932.1 - 6.4e-26 89.6 0.0 1.1e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 RLN52932.1 - 0.25 11.9 13.6 0.48 11.0 13.6 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 PRR20 PF15708.5 RLN52932.1 - 0.5 10.2 4.7 0.8 9.6 4.7 1.2 1 0 0 1 1 1 0 Proline-rich protein family 20 FtsH_ext PF06480.15 RLN52933.1 - 4.8e-10 39.8 0.0 1.6e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 FtsH Extracellular SecG PF03840.14 RLN52933.1 - 1.9 8.6 8.7 4.5 7.4 0.7 3.3 3 0 0 3 3 3 0 Preprotein translocase SecG subunit Pkinase_Tyr PF07714.17 RLN52946.1 - 0.022 14.0 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Elicitin PF00964.17 RLN52947.1 - 2.1e-20 72.6 2.9 2.1e-20 72.6 2.9 1.9 1 1 2 3 3 3 1 Elicitin YabA PF06156.13 RLN52948.1 - 0.6 10.8 3.3 1.6 9.4 2.0 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Pkinase_Tyr PF07714.17 RLN52949.1 - 1.3e-22 80.3 0.0 1.7e-20 73.4 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN52949.1 - 5.9e-21 75.0 0.0 1.9e-20 73.4 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain Arm PF00514.23 RLN52949.1 - 2.5e-06 27.3 0.0 0.01 15.8 0.0 4.3 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN52949.1 - 0.00011 22.5 1.2 0.14 12.6 0.4 3.4 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.22 RLN52949.1 - 0.11 12.8 2.4 14 6.2 0.0 4.2 5 1 0 5 5 5 0 HEAT repeat DUF370 PF04025.12 RLN52949.1 - 0.17 12.0 0.0 0.88 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF370) HEAT_EZ PF13513.6 RLN52949.1 - 0.29 11.7 2.6 2.5 8.7 1.4 2.9 2 1 0 2 2 2 0 HEAT-like repeat Myb_DNA-binding PF00249.31 RLN52955.1 - 3.9e-10 39.7 0.0 6.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN52955.1 - 0.0046 17.2 0.1 0.0079 16.4 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2390 PF09523.10 RLN52955.1 - 0.12 12.8 1.1 0.17 12.2 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) DUF4505 PF14956.6 RLN52967.1 - 2.7e-42 144.5 0.0 3.5e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) HA2 PF04408.23 RLN52968.1 - 3.5e-24 85.2 0.1 3.5e-24 85.2 0.1 3.1 2 1 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RLN52968.1 - 1e-23 83.5 0.0 2e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 RLN52968.1 - 1.9e-13 50.7 0.0 7.6e-13 48.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain S1 PF00575.23 RLN52968.1 - 3.6e-10 40.0 1.0 8.3e-10 38.9 1.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 RLN52968.1 - 1.5e-07 31.3 0.3 3.4e-07 30.2 0.3 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RLN52968.1 - 2.1e-07 31.3 0.1 5.6e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RLN52968.1 - 0.0005 20.4 0.3 0.0012 19.3 0.3 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RLN52968.1 - 0.0018 18.0 0.1 0.0058 16.4 0.1 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 RLN52968.1 - 0.0019 17.3 0.4 0.0077 15.3 0.1 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 RLN52968.1 - 0.01 16.0 1.4 0.45 10.6 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain PhoH PF02562.16 RLN52968.1 - 0.023 14.2 0.2 0.059 12.8 0.2 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 RLN52968.1 - 0.039 14.0 2.0 0.38 10.8 0.4 3.0 3 1 0 3 3 3 0 AAA domain Microtub_bd PF16796.5 RLN52968.1 - 0.048 13.6 0.2 1.5 8.8 0.1 2.5 2 0 0 2 2 2 0 Microtubule binding ABC_tran PF00005.27 RLN52968.1 - 0.049 14.2 2.4 1 9.9 0.2 3.3 2 1 0 3 3 3 0 ABC transporter AAA_7 PF12775.7 RLN52968.1 - 0.056 12.9 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 RLN52968.1 - 0.3 11.5 1.0 3.9 7.9 0.5 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) adh_short PF00106.25 RLN52969.1 - 6.2e-44 149.8 0.1 7.8e-44 149.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN52969.1 - 1.1e-28 100.4 0.1 1.4e-28 100.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN52969.1 - 2.5e-14 53.6 1.3 4.4e-14 52.8 1.3 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 RLN52969.1 - 0.0056 16.0 0.0 0.0087 15.4 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 RLN52969.1 - 0.038 13.4 0.1 0.37 10.2 0.1 2.3 1 1 2 3 3 3 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 RLN52969.1 - 0.041 14.3 0.2 0.064 13.7 0.2 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding DFP PF04127.15 RLN52969.1 - 0.042 13.7 1.3 0.094 12.5 1.3 1.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.18 RLN52969.1 - 0.16 11.9 0.2 0.24 11.3 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cpn60_TCP1 PF00118.24 RLN52970.1 - 1e-66 225.6 2.4 1.1e-66 225.4 2.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-H2C2_2 PF13465.6 RLN52971.1 - 5.3e-11 42.4 21.9 4.2e-07 30.1 1.3 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 RLN52971.1 - 8.2e-07 29.2 23.9 0.0006 20.1 3.6 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN52971.1 - 5.7e-06 26.7 21.9 0.0082 16.9 4.1 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 RLN52971.1 - 0.00097 19.4 7.7 0.0065 16.8 7.5 2.2 1 1 2 3 3 3 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 RLN52971.1 - 0.001 19.6 6.6 0.007 17.0 0.7 3.4 3 1 1 4 4 4 1 FOXP coiled-coil domain zf-met PF12874.7 RLN52971.1 - 0.0076 16.6 2.6 0.18 12.2 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RLN52971.1 - 0.062 13.6 2.5 1.6 9.2 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_Hakai PF18408.1 RLN52971.1 - 0.1 12.3 0.0 0.1 12.3 0.0 3.0 4 0 0 4 4 4 0 C2H2 Hakai zinc finger domain RPAP2_Rtr1 PF04181.13 RLN52971.1 - 0.65 10.3 6.3 2.1 8.7 2.2 2.5 1 1 1 2 2 2 0 Rtr1/RPAP2 family B12D PF06522.11 RLN52972.1 - 2.4e-09 36.9 0.0 3.1e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit ANAPC8 PF04049.13 RLN52973.1 - 0.051 13.6 0.3 0.19 11.7 0.0 1.8 1 1 1 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 CRF-BP PF05428.11 RLN52990.1 - 0.087 11.6 0.1 0.09 11.5 0.1 1.2 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) Pkinase_Tyr PF07714.17 RLN52995.1 - 2.4e-43 148.3 0.1 1.8e-22 79.9 0.0 2.4 1 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN52995.1 - 6.6e-36 124.0 0.0 2.3e-35 122.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 RLN52995.1 - 0.0046 16.0 0.2 0.021 13.8 0.1 2.1 1 1 1 2 2 2 1 Haspin like kinase domain APH PF01636.23 RLN52995.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family CENP-Q PF13094.6 RLN52996.1 - 0.076 13.2 4.4 0.11 12.6 4.4 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Pex14_N PF04695.13 RLN52996.1 - 1.2 9.8 5.2 0.16 12.6 0.5 1.9 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4413 PF14372.6 RLN53016.1 - 0.0017 18.7 0.0 0.0054 17.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) DUF659 PF04937.15 RLN53016.1 - 0.049 13.5 0.3 1.3 8.9 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF 659) IFT43 PF15305.6 RLN53021.1 - 5.7e-18 65.4 10.7 4.3e-16 59.3 10.7 3.1 1 1 0 1 1 1 1 Intraflagellar transport protein 43 DUF866 PF05907.13 RLN53022.1 - 6.8e-34 117.0 0.0 7.9e-34 116.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) ABC2_membrane PF01061.24 RLN53023.1 - 3.2e-32 111.7 47.8 7.5e-29 100.6 30.8 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN53023.1 - 4.2e-15 56.5 0.0 6.2e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter PDR_CDR PF06422.12 RLN53023.1 - 9.5e-08 31.8 7.3 7.8e-07 28.9 0.0 3.0 3 0 0 3 3 2 2 CDR ABC transporter AAA_21 PF13304.6 RLN53023.1 - 1.8e-05 24.7 0.1 0.027 14.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system PDR_assoc PF08370.11 RLN53023.1 - 7.4e-05 22.4 13.1 0.0043 16.8 0.0 3.7 3 0 0 3 3 3 2 Plant PDR ABC transporter associated ABC2_membrane_3 PF12698.7 RLN53023.1 - 0.0023 17.1 13.7 0.0023 17.1 13.7 3.2 2 2 1 3 3 3 1 ABC-2 family transporter protein AAA_29 PF13555.6 RLN53023.1 - 0.012 15.4 1.1 0.03 14.1 1.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN53023.1 - 0.014 15.3 0.3 0.028 14.3 0.3 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 RLN53023.1 - 0.019 14.5 0.1 0.035 13.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 RLN53023.1 - 0.066 13.7 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain MukB PF04310.12 RLN53023.1 - 0.23 11.2 0.5 0.43 10.4 0.5 1.3 1 0 0 1 1 1 0 MukB N-terminal zf-RING_2 PF13639.6 RLN53034.1 - 0.0015 18.8 8.6 0.0015 18.8 8.6 2.7 2 1 0 2 2 2 1 Ring finger domain zf-RING_4 PF14570.6 RLN53034.1 - 0.012 15.4 6.6 0.012 15.4 6.6 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Rop-like PF05082.13 RLN53034.1 - 0.022 14.6 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Rop-like zf-C3HC4 PF00097.25 RLN53034.1 - 1.2 9.1 12.6 0.3 11.0 6.8 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN53034.1 - 8.4 6.3 17.3 0.13 12.2 4.3 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 RLN53044.1 - 1.2e-160 522.6 35.9 2.7e-22 79.2 0.3 10.7 1 1 10 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.30 RLN53044.1 - 9.8e-132 424.2 28.3 2.1e-07 31.1 0.0 22.1 22 0 0 22 22 22 22 Ankyrin repeat Ank_3 PF13606.6 RLN53044.1 - 7.7e-131 409.9 23.3 5e-06 26.5 0.0 22.1 22 0 0 22 22 22 22 Ankyrin repeat Ank_4 PF13637.6 RLN53044.1 - 7.1e-126 409.1 66.8 2e-10 41.0 0.1 16.3 3 3 17 21 21 21 21 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN53044.1 - 1.6e-108 353.4 46.6 7.3e-08 32.5 0.1 21.2 1 1 19 21 21 21 21 Ankyrin repeats (many copies) VWA_3_C PF18571.1 RLN53044.1 - 6.4e-10 38.7 20.8 18 5.3 0.0 15.4 18 0 0 18 18 18 0 von Willebrand factor type A C-terminal domain MEDS PF14417.6 RLN53044.1 - 7.6e-10 38.9 10.3 0.45 10.3 0.1 7.9 1 1 11 12 12 12 5 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Nepo_coat_C PF03688.14 RLN53044.1 - 1.6e-07 31.3 23.2 3.6 7.4 0.1 10.2 1 1 9 13 13 13 2 Nepovirus coat protein, C-terminal domain YlzJ PF14035.6 RLN53044.1 - 3.8e-07 30.2 0.0 2.8e+02 1.8 0.0 10.7 16 0 0 16 16 15 0 YlzJ-like protein Imm_superinfect PF14373.6 RLN53044.1 - 0.00011 22.1 24.7 20 5.2 0.0 14.9 19 0 0 19 19 19 0 Superinfection immunity protein Urease_linker PF18473.1 RLN53044.1 - 0.00042 20.1 0.3 1.7e+02 2.2 0.0 7.8 11 0 0 11 11 11 0 Urease subunit beta-alpha linker domain SpoIIIAH PF12685.7 RLN53044.1 - 1.2 8.9 8.3 1.2e+02 2.3 0.0 6.4 9 0 0 9 9 9 0 SpoIIIAH-like protein DUF3368 PF11848.8 RLN53044.1 - 3.1 7.6 6.1 4.5e+02 0.7 0.0 6.7 7 0 0 7 7 7 0 Domain of unknown function (DUF3368) Myc_N PF01056.18 RLN53097.1 - 1.4 8.8 5.8 6.2 6.6 2.9 2.2 2 0 0 2 2 2 0 Myc amino-terminal region zf-NOSIP PF15906.5 RLN53098.1 - 8.9e-11 41.8 0.1 1.7e-10 40.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_2 PF13639.6 RLN53098.1 - 0.0011 19.3 4.5 0.086 13.2 0.2 2.4 2 0 0 2 2 2 2 Ring finger domain Prok-RING_4 PF14447.6 RLN53098.1 - 0.082 12.8 5.6 3.9 7.4 0.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zinc_ribbon_13 PF09855.9 RLN53098.1 - 0.083 13.1 0.1 12 6.1 0.1 2.6 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-RING_UBOX PF13445.6 RLN53098.1 - 0.1 12.6 3.7 0.13 12.3 0.3 2.4 2 0 0 2 2 2 0 RING-type zinc-finger APG6_N PF17675.1 RLN53098.1 - 0.22 12.1 7.7 0.32 11.5 7.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2093 PF09866.9 RLN53098.1 - 0.65 9.5 3.2 3 7.3 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2093) CLN3 PF02487.17 RLN53099.1 - 8.7e-79 265.4 10.0 1.1e-78 265.1 10.0 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 RLN53099.1 - 0.11 11.4 43.7 0.21 10.5 43.6 1.5 1 1 0 1 1 1 0 Major Facilitator Superfamily Glyoxalase_4 PF13669.6 RLN53102.1 - 2.2e-19 69.7 0.0 3.7e-19 69.0 0.0 1.4 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 RLN53102.1 - 0.1 12.8 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Gti1_Pac2 PF09729.9 RLN53133.1 - 0.036 14.1 0.8 0.052 13.6 0.8 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family FYVE PF01363.21 RLN53134.1 - 0.049 13.8 5.7 0.1 12.7 5.7 1.6 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN53134.1 - 0.065 13.4 3.3 0.2 11.9 3.3 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger Cys_rich_CPXG PF14255.6 RLN53134.1 - 0.69 9.8 0.1 0.69 9.8 0.1 3.0 3 0 0 3 3 3 0 Cysteine-rich CPXCG IBR PF01485.21 RLN53134.1 - 0.9 9.8 5.9 0.47 10.7 2.3 2.2 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 RLN53134.1 - 1.7 8.7 7.4 18 5.5 4.0 2.5 2 0 0 2 2 2 0 RING-type zinc-finger Zn-ribbon_8 PF09723.10 RLN53134.1 - 4.1 7.6 5.6 1.4 9.1 1.9 2.3 2 1 1 3 3 3 0 Zinc ribbon domain 5_3_exonuc_N PF02739.16 RLN53141.1 - 2.2e-27 95.9 0.0 3.3e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 RLN53141.1 - 5.2e-13 49.4 0.0 8.4e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold LIF_OSM PF01291.17 RLN53141.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 LIF / OSM family Acyl-CoA_ox_N PF14749.6 RLN53142.1 - 9.9e-11 42.3 0.3 1.1e-10 42.2 0.3 1.0 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Beach PF02138.18 RLN53149.1 - 1.1e-33 116.8 0.0 2.1e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 RLN53149.1 - 0.00014 22.6 0.1 0.0011 19.8 0.1 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat PQQ_2 PF13360.6 RLN53149.1 - 0.00014 21.5 4.2 0.00033 20.3 4.2 1.6 1 0 0 1 1 1 1 PQQ-like domain Pkinase PF00069.25 RLN53149.1 - 0.022 14.1 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain PQQ_3 PF13570.6 RLN53149.1 - 0.46 11.1 3.7 1 9.9 1.9 2.7 2 0 0 2 2 2 0 PQQ-like domain FAM104 PF15434.6 RLN53149.1 - 7.8 7.1 7.1 0.45 11.1 0.2 2.4 3 0 0 3 3 3 0 Family 104 Pkinase PF00069.25 RLN53150.1 - 5.5e-51 173.5 0.0 8.2e-41 140.1 0.0 3.3 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 RLN53150.1 - 1.3e-20 73.8 0.0 1.2e-13 51.0 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 RLN53150.1 - 0.0011 18.4 0.1 0.025 13.9 0.1 2.6 3 0 0 3 3 3 1 Kinase-like FTA2 PF13095.6 RLN53150.1 - 0.011 15.3 0.0 0.26 10.9 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RLN53150.1 - 0.022 14.7 0.4 0.079 12.9 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ank_2 PF12796.7 RLN53151.1 - 8.6e-33 112.8 8.0 3.1e-09 37.3 0.0 5.7 2 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN53151.1 - 4.4e-25 87.7 3.9 0.0012 19.4 0.0 7.1 5 2 2 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN53151.1 - 1.2e-20 73.2 8.2 1e-05 25.7 0.0 6.3 5 1 0 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN53151.1 - 1.4e-18 65.0 6.5 0.02 15.4 0.0 8.3 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 RLN53151.1 - 5.1e-18 64.6 15.0 0.029 14.8 0.0 9.3 9 1 1 10 10 10 6 Ankyrin repeat IQ PF00612.27 RLN53151.1 - 3.8e-12 44.9 109.1 0.0081 15.9 1.6 14.2 13 0 0 13 13 13 8 IQ calmodulin-binding motif TPR_2 PF07719.17 RLN53151.1 - 0.051 13.7 2.4 0.39 10.9 2.4 2.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Elicitin PF00964.17 RLN53152.1 - 1.7e-09 37.7 5.1 1.7e-09 37.7 5.1 1.7 2 0 0 2 2 2 1 Elicitin Lin-8 PF03353.15 RLN53152.1 - 0.12 12.0 6.1 0.15 11.6 6.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SDA1 PF05285.12 RLN53152.1 - 0.39 10.1 8.7 0.47 9.8 8.7 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 RLN53152.1 - 0.39 10.0 14.4 0.49 9.7 14.4 1.1 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 RLN53152.1 - 0.53 9.8 7.6 0.6 9.6 7.6 1.3 1 0 0 1 1 1 0 PPP4R2 Plasmodium_Vir PF05795.11 RLN53152.1 - 0.53 9.7 3.4 0.6 9.5 3.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Macoilin PF09726.9 RLN53152.1 - 1.4 7.4 10.2 1.4 7.4 10.2 1.1 1 0 0 1 1 1 0 Macoilin family Raftlin PF15250.6 RLN53152.1 - 1.4 7.5 5.0 1.7 7.3 5.0 1.1 1 0 0 1 1 1 0 Raftlin Hid1 PF12722.7 RLN53152.1 - 2.3 6.2 5.4 2.7 6.0 5.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GREB1 PF15782.5 RLN53152.1 - 2.8 5.0 8.1 2.7 5.0 8.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Nop14 PF04147.12 RLN53152.1 - 5.2 5.1 9.5 6.2 4.9 9.5 1.1 1 0 0 1 1 1 0 Nop14-like family Tub_N PF16322.5 RLN53152.1 - 5.4 7.4 13.0 7.6 6.9 13.0 1.2 1 0 0 1 1 1 0 Tubby N-terminal PQ-loop PF04193.14 RLN53153.1 - 3e-33 113.4 13.6 4.7e-19 67.9 5.7 2.6 2 0 0 2 2 2 2 PQ loop repeat Elicitin PF00964.17 RLN53154.1 - 3.8e-16 59.0 4.4 5.7e-16 58.4 4.4 1.3 1 0 0 1 1 1 1 Elicitin EF-hand_6 PF13405.6 RLN53155.1 - 1.2e-14 52.9 3.7 0.012 15.5 0.0 7.2 6 0 0 6 6 6 4 EF-hand domain EF-hand_7 PF13499.6 RLN53155.1 - 2.6e-13 50.2 5.5 0.00034 21.0 0.0 7.9 7 1 1 8 8 8 3 EF-hand domain pair EF-hand_1 PF00036.32 RLN53155.1 - 4.7e-08 32.0 2.5 0.25 11.0 0.0 6.6 7 0 0 7 7 7 3 EF hand EF-hand_8 PF13833.6 RLN53155.1 - 1.1e-07 31.6 1.7 1 9.3 0.0 6.7 7 0 0 7 7 7 3 EF-hand domain pair EF-hand_2 PF09068.11 RLN53155.1 - 0.00015 21.9 0.0 0.11 12.7 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 RLN53155.1 - 0.04 13.4 0.2 8.8 6.0 0.0 4.1 5 0 0 5 5 5 0 EF hand EGF_2 PF07974.13 RLN53156.1 - 0.00014 22.1 23.2 0.00036 20.8 10.4 4.1 3 1 1 4 4 4 2 EGF-like domain Laminin_EGF PF00053.24 RLN53156.1 - 0.0067 16.6 4.7 0.0067 16.6 4.7 2.6 3 1 0 3 3 3 1 Laminin EGF domain zf-CCCH_2 PF14608.6 RLN53156.1 - 0.048 14.1 1.3 0.22 12.1 0.2 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Tim17 PF02466.19 RLN53157.1 - 4e-06 27.2 0.7 5.2e-06 26.8 0.7 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ATP-synt_I PF03899.15 RLN53157.1 - 0.28 11.6 3.3 0.78 10.1 2.7 2.0 1 1 1 2 2 2 0 ATP synthase I chain B12D PF06522.11 RLN53158.1 - 1.5e-13 50.3 1.8 2.3e-13 49.7 0.0 1.9 2 0 0 2 2 2 1 NADH-ubiquinone reductase complex 1 MLRQ subunit TMEM65 PF10507.9 RLN53159.1 - 2.4e-38 130.4 4.0 2.4e-38 130.4 4.0 1.5 2 0 0 2 2 2 1 Transmembrane protein 65 EF-hand_1 PF00036.32 RLN53159.1 - 0.00031 20.1 0.0 0.00051 19.4 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 RLN53159.1 - 0.042 13.8 0.1 0.084 12.9 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 RLN53159.1 - 0.072 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 RLN53159.1 - 0.22 11.1 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 EF hand EamA PF00892.20 RLN53160.1 - 0.0024 18.1 4.9 0.0031 17.7 4.9 1.2 1 0 0 1 1 1 1 EamA-like transporter family Phage_integrase PF00589.22 RLN53164.1 - 0.0083 15.9 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 Phage integrase family Y_Y_Y PF07495.13 RLN53165.1 - 0.0018 18.2 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 Y_Y_Y domain TcfC PF16967.5 RLN53165.1 - 0.13 11.8 0.3 0.25 10.8 0.0 1.6 2 0 0 2 2 2 0 E-set like domain Ank_4 PF13637.6 RLN53193.1 - 1.5e-26 92.4 9.4 1.1e-05 25.9 0.0 6.3 3 1 5 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN53193.1 - 4.9e-24 84.1 12.6 0.0027 18.0 0.0 8.6 4 2 6 10 10 10 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN53193.1 - 8.4e-22 77.6 1.3 8.5e-07 29.5 0.1 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN53193.1 - 9.6e-14 50.2 0.2 0.75 10.5 0.0 9.7 11 0 0 11 11 11 1 Ankyrin repeat Ank PF00023.30 RLN53193.1 - 0.0036 17.7 0.3 51 4.6 0.0 6.1 3 3 0 3 3 3 0 Ankyrin repeat PTAC PF06130.12 RLN53201.1 - 0.024 14.8 4.7 1.8 8.8 0.4 3.6 4 0 0 4 4 4 0 Phosphate propanoyltransferase Pkinase_Tyr PF07714.17 RLN53246.1 - 1.5e-41 142.4 0.0 1.9e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN53246.1 - 4.7e-41 140.9 0.0 5.7e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 RLN53246.1 - 0.0017 17.2 0.0 0.003 16.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN53246.1 - 0.0025 17.8 0.3 0.005 16.8 0.3 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 RLN53246.1 - 0.0027 17.3 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 RLN53246.1 - 0.012 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 RLN53246.1 - 0.1 12.0 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gp_dh_N PF00044.24 RLN53272.1 - 4.5e-39 132.9 0.0 6.1e-39 132.4 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 RLN53272.1 - 0.12 12.5 0.1 0.24 11.5 0.1 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CorA PF01544.18 RLN53352.1 - 1.1e-37 129.9 0.0 1.4e-32 113.2 0.0 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein NadA PF02445.16 RLN53352.1 - 1.9e-26 92.9 0.3 3.2e-26 92.2 0.3 1.3 1 0 0 1 1 1 1 Quinolinate synthetase A protein EF-hand_7 PF13499.6 RLN53352.1 - 0.00037 20.9 0.1 0.00087 19.7 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN53352.1 - 0.0016 17.8 0.1 0.0035 16.8 0.1 1.6 1 0 0 1 1 1 1 EF hand ATP_bind_2 PF03668.15 RLN53352.1 - 0.02 14.2 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family EF-hand_8 PF13833.6 RLN53352.1 - 0.025 14.4 0.1 0.051 13.4 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair MRP-S33 PF08293.11 RLN53352.1 - 0.046 14.0 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit S27 EF-hand_6 PF13405.6 RLN53352.1 - 0.052 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain Pkinase PF00069.25 RLN53353.1 - 3.6e-40 138.0 0.0 2.2e-38 132.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN53353.1 - 2e-37 128.9 0.0 8.2e-35 120.3 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 RLN53353.1 - 9e-05 22.5 0.0 0.0037 17.2 0.0 3.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Arm PF00514.23 RLN53354.1 - 5.1e-47 156.5 8.9 7.7e-08 32.1 0.1 8.3 8 0 0 8 8 8 7 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 RLN53354.1 - 1.3e-11 44.3 3.6 0.0064 16.5 0.0 5.7 3 1 3 7 7 7 5 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 RLN53354.1 - 2.1e-09 37.7 16.9 0.0029 18.1 0.5 5.7 5 2 1 6 6 6 3 HEAT-like repeat HEAT_2 PF13646.6 RLN53354.1 - 8.3e-07 29.3 10.0 9.9e-05 22.7 0.8 4.5 1 1 3 5 5 5 4 HEAT repeats HEAT_PBS PF03130.16 RLN53354.1 - 1.5e-06 28.3 32.5 15 6.6 0.0 9.4 10 0 0 10 10 10 4 PBS lyase HEAT-like repeat HEAT PF02985.22 RLN53354.1 - 0.00024 21.1 11.2 11 6.6 0.1 7.3 9 0 0 9 9 9 2 HEAT repeat UNC45-central PF11701.8 RLN53354.1 - 0.12 12.3 0.3 2.2 8.2 0.1 2.7 2 1 1 3 3 3 0 Myosin-binding striated muscle assembly central DUF2153 PF09921.9 RLN53354.1 - 0.18 11.6 0.2 48 3.8 0.0 4.2 5 0 0 5 5 5 0 Uncharacterized protein conserved in archaea (DUF2153) Myb_DNA-binding PF00249.31 RLN53400.1 - 4e-13 49.3 0.6 1.3e-12 47.7 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Rap1_C PF11626.8 RLN53400.1 - 0.0016 18.5 0.1 0.0027 17.8 0.1 1.3 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_6 PF13921.6 RLN53400.1 - 0.045 14.0 0.2 0.076 13.3 0.2 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF1765 PF08578.10 RLN53415.1 - 8.4e-19 68.3 0.0 1.8e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) PHD20L1_u1 PF16660.5 RLN53415.1 - 0.074 13.8 1.3 6.7 7.5 0.0 2.6 2 0 0 2 2 2 0 PHD finger protein 20-like protein 1 TauE PF01925.19 RLN53416.1 - 5.2e-26 91.7 36.5 1.6e-17 63.9 5.5 2.5 3 0 0 3 3 3 2 Sulfite exporter TauE/SafE Runt PF00853.19 RLN53416.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Runt domain ACC_epsilon PF13822.6 RLN53416.1 - 8.9 7.1 7.4 0.96 10.2 1.5 2.5 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit His_Phos_2 PF00328.22 RLN53417.1 - 1e-08 35.0 0.1 7e-05 22.3 0.0 2.8 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.25 RLN53418.1 - 1e-35 123.4 0.0 1.5e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN53418.1 - 1.4e-33 116.2 0.0 2e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN53418.1 - 0.012 15.6 0.5 0.049 13.6 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN53418.1 - 0.046 13.1 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN53418.1 - 0.06 12.7 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF4199 PF13858.6 RLN53419.1 - 2.7 8.4 7.8 0.48 10.8 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Pkinase PF00069.25 RLN53421.1 - 7.9e-54 182.8 0.0 6.2e-51 173.3 0.0 3.2 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN53421.1 - 1.4e-22 80.2 0.1 8.1e-19 67.9 0.0 3.3 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RLN53421.1 - 0.015 14.6 0.0 0.048 13.0 0.0 1.8 1 1 0 1 1 1 0 Kinase-like TruD PF01142.18 RLN53422.1 - 1.2e-65 222.0 0.0 4e-63 213.7 0.0 3.6 2 1 1 3 3 3 3 tRNA pseudouridine synthase D (TruD) Mito_carr PF00153.27 RLN53423.1 - 2.9e-18 65.6 0.8 1.7e-13 50.3 0.1 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein TH1 PF04858.13 RLN53432.1 - 1.2e-42 146.4 1.9 2.2e-23 82.8 0.2 2.2 2 0 0 2 2 2 2 TH1 protein HipN PF18253.1 RLN53432.1 - 8.2e-05 22.2 0.0 0.00031 20.4 0.0 2.0 1 0 0 1 1 1 1 Hsp70-interacting protein N N-terminal domain TH1 PF04858.13 RLN53433.1 - 9.5e-22 77.4 0.1 1.7e-21 76.5 0.1 1.4 1 0 0 1 1 1 1 TH1 protein WW PF00397.26 RLN53433.1 - 3.8e-18 65.3 11.7 4.1e-09 36.4 1.9 2.6 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 RLN53433.1 - 9 6.6 8.4 11 6.3 0.2 3.3 3 0 0 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain GFA PF04828.14 RLN53438.1 - 4.7e-10 39.7 0.8 4.7e-10 39.7 0.8 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L37e PF01907.19 RLN53438.1 - 0.017 15.3 0.2 0.043 14.0 0.2 1.6 1 0 0 1 1 1 0 Ribosomal protein L37e JHY PF15261.6 RLN53441.1 - 8.6e-21 75.0 2.1 8.6e-21 75.0 2.1 3.1 2 1 0 3 3 3 1 Jhy protein Arm PF00514.23 RLN53442.1 - 4.1e-46 153.7 21.8 4.9e-08 32.7 0.0 15.1 15 0 0 15 15 15 9 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 RLN53442.1 - 2.7e-12 46.6 1.6 0.27 11.3 0.0 7.7 5 2 4 9 9 9 3 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 RLN53442.1 - 2.4e-07 30.5 0.0 0.14 11.6 0.0 4.4 3 1 2 5 5 5 4 Armadillo-like HEAT PF02985.22 RLN53442.1 - 6.1e-07 29.2 22.3 0.18 12.2 0.0 11.3 12 2 1 13 13 13 2 HEAT repeat HEAT_EZ PF13513.6 RLN53442.1 - 1.7e-06 28.4 35.9 0.061 13.9 0.2 9.3 6 3 4 10 10 10 4 HEAT-like repeat HEAT_2 PF13646.6 RLN53442.1 - 4.5e-06 27.0 43.4 0.062 13.7 1.3 7.7 1 1 8 10 10 10 7 HEAT repeats RPAP1_C PF08620.10 RLN53442.1 - 7.6e-06 26.0 5.9 2.3 8.4 0.1 7.3 9 0 0 9 9 9 2 RPAP1-like, C-terminal DUF5578 PF17741.1 RLN53442.1 - 0.00027 20.5 0.9 11 5.3 0.0 4.1 3 1 1 4 4 4 2 Family of unknown function (DUF5578) UNC45-central PF11701.8 RLN53442.1 - 0.0013 18.7 7.8 0.2 11.6 0.3 5.1 4 2 2 6 6 6 1 Myosin-binding striated muscle assembly central Vitellogenin_N PF01347.22 RLN53442.1 - 0.17 10.2 0.0 0.31 9.4 0.0 1.4 1 0 0 1 1 1 0 Lipoprotein amino terminal region Succ_CoA_lig PF13607.6 RLN53442.1 - 1 9.1 15.1 9.2 6.1 0.6 5.9 3 3 6 9 9 9 0 Succinyl-CoA ligase like flavodoxin domain RNase_H PF00075.24 RLN53458.1 - 1.5e-24 86.8 0.1 1.2e-17 64.4 0.0 2.2 2 0 0 2 2 2 2 RNase H DUF4060 PF13269.6 RLN53458.1 - 0.017 15.2 0.0 0.092 12.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4060) KinB_sensor PF16767.5 RLN53462.1 - 0.024 15.1 3.9 0.024 15.1 3.9 3.1 1 1 1 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB SCP2_2 PF13530.6 RLN53462.1 - 0.042 14.2 3.1 0.054 13.9 0.6 2.4 2 1 1 3 3 3 0 Sterol carrier protein domain CagY_I PF14585.6 RLN53462.1 - 0.13 12.3 1.4 0.24 11.5 0.2 2.1 2 0 0 2 2 2 0 CagY type 1 repeat Pox_A6 PF04924.12 RLN53462.1 - 0.21 10.5 4.5 0.41 9.5 0.2 2.1 1 1 0 2 2 2 0 Poxvirus A6 protein Spectrin_like PF18373.1 RLN53462.1 - 0.23 11.5 3.6 1.1 9.4 0.1 3.2 2 1 1 3 3 3 0 Spectrin like domain PL48 PF15903.5 RLN53462.1 - 0.31 10.0 7.1 0.092 11.7 1.6 2.0 1 1 1 2 2 2 0 Filopodia upregulated, FAM65 ApoC-I PF04691.12 RLN53462.1 - 1.2 9.2 4.9 8.2 6.4 0.1 3.9 4 1 1 5 5 5 0 Apolipoprotein C-I (ApoC-1) DUF4936 PF16290.5 RLN53462.1 - 1.2 9.8 11.6 0.09 13.5 1.6 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4936) MCPVI PF02993.14 RLN53462.1 - 1.3 8.8 12.9 4.8 6.9 4.4 2.2 1 1 1 2 2 2 0 Minor capsid protein VI AMP-binding_C_2 PF14535.6 RLN53462.1 - 3.3 8.1 8.5 0.6 10.5 0.5 3.0 2 1 1 3 3 3 0 AMP-binding enzyme C-terminal domain AlkA_N PF06029.11 RLN53462.1 - 3.7 7.9 6.0 4.1 7.7 1.2 2.3 2 0 0 2 2 2 0 AlkA N-terminal domain MINDY_DUB PF04424.13 RLN53462.1 - 4.3 7.4 5.9 8.2 6.5 0.4 2.8 1 1 1 2 2 2 0 MINDY deubiquitinase MIP PF00230.20 RLN53479.1 - 1.3e-56 191.9 5.6 1.7e-56 191.5 5.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein Polysacc_synt_C PF14667.6 RLN53479.1 - 0.0016 18.5 11.2 1.4 9.0 2.2 3.3 3 1 0 3 3 3 3 Polysaccharide biosynthesis C-terminal domain Phage_holin_8 PF16931.5 RLN53479.1 - 0.066 13.2 0.1 0.41 10.6 0.0 2.1 2 0 0 2 2 2 0 Putative phage holin MIP PF00230.20 RLN53480.1 - 4.4e-50 170.5 13.5 5.6e-50 170.2 13.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 RLN53481.1 - 2.5e-56 190.9 5.3 3.5e-56 190.5 5.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein Phage_holin_8 PF16931.5 RLN53481.1 - 0.0073 16.3 0.1 0.02 14.9 0.1 1.7 1 0 0 1 1 1 1 Putative phage holin DUF417 PF04224.12 RLN53481.1 - 0.059 12.9 0.1 0.096 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF417 DUF4064 PF13273.6 RLN53481.1 - 1.3 9.3 7.2 0.49 10.7 2.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) MIP PF00230.20 RLN53482.1 - 4e-39 134.6 10.1 5e-39 134.3 10.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 RLN53483.1 - 4.3e-55 186.9 7.5 5.6e-55 186.5 7.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 RLN53484.1 - 9e-55 185.8 6.5 1.1e-54 185.5 6.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein Aminotran_4 PF01063.19 RLN53499.1 - 9.5e-19 68.1 0.0 5.2e-18 65.7 0.0 1.9 1 1 0 1 1 1 1 Amino-transferase class IV Ntox30 PF15532.6 RLN53499.1 - 0.081 13.3 0.0 15 6.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial toxin 30 IQ PF00612.27 RLN53500.1 - 5.5 7.1 14.6 0.064 13.1 2.4 3.8 3 0 0 3 3 3 0 IQ calmodulin-binding motif Ank_2 PF12796.7 RLN53501.1 - 7.6e-27 93.7 0.0 1.5e-08 35.1 0.0 3.6 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN53501.1 - 3e-26 91.4 5.5 3e-11 43.6 0.0 4.8 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN53501.1 - 5.2e-24 83.6 0.2 1.7e-05 25.1 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 RLN53501.1 - 4.2e-20 71.5 0.8 4.5e-07 30.0 0.0 4.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN53501.1 - 8.1e-20 68.8 0.7 0.0016 18.8 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat GEN1_C PF18380.1 RLN53501.1 - 0.061 14.2 9.8 2.2 9.2 0.1 2.5 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain tRNA-synt_2c PF01411.19 RLN53501.1 - 0.063 11.8 0.1 0.11 11.0 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class II (A) SDA1 PF05285.12 RLN53501.1 - 0.48 9.8 16.1 0.027 13.9 6.4 2.1 2 0 0 2 2 2 0 SDA1 CPSF100_C PF13299.6 RLN53501.1 - 1.8 8.7 5.6 4 7.6 1.6 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal TRAP_alpha PF03896.16 RLN53501.1 - 8.8 5.4 7.5 17 4.5 7.5 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SecE PF00584.20 RLN53502.1 - 2.2e-11 43.5 0.6 0.00015 21.6 0.0 2.1 1 1 1 2 2 2 2 SecE/Sec61-gamma subunits of protein translocation complex Rad52_Rad22 PF04098.15 RLN53503.1 - 3.8e-38 130.8 0.0 5.5e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein PI3_PI4_kinase PF00454.27 RLN53504.1 - 2.7e-32 112.5 0.0 2.5e-23 83.2 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PH PF00169.29 RLN53504.1 - 0.00031 21.2 0.0 0.0013 19.2 0.0 2.0 2 0 0 2 2 2 1 PH domain DUF4135 PF13575.6 RLN53504.1 - 0.048 13.0 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Rap_GAP PF02145.15 RLN53505.1 - 7.9e-09 35.3 0.0 2.8e-08 33.5 0.0 1.9 1 1 0 1 1 1 1 Rap/ran-GAP Asp PF00026.23 RLN53595.1 - 3.2e-37 128.6 7.1 7e-37 127.5 7.1 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RLN53595.1 - 2.5e-06 27.8 1.8 6.5e-05 23.2 0.3 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 RLN53595.1 - 0.00019 21.3 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal DUF4381 PF14316.6 RLN53595.1 - 0.0038 17.5 1.7 0.0064 16.7 1.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) DUF2681 PF10883.8 RLN53595.1 - 0.052 14.0 1.0 0.099 13.1 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Peptidase_M56 PF05569.11 RLN53595.1 - 0.12 11.5 0.4 0.19 10.9 0.4 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 Elicitin PF00964.17 RLN53596.1 - 1.9e-19 69.5 1.3 2.6e-19 69.1 1.3 1.2 1 0 0 1 1 1 1 Elicitin Elicitin PF00964.17 RLN53597.1 - 2e-38 130.3 8.9 2.7e-20 72.2 0.8 2.2 2 0 0 2 2 2 2 Elicitin Fer2_4 PF13510.6 RLN53597.1 - 0.1 12.7 0.1 17 5.6 0.0 3.0 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain Elicitin PF00964.17 RLN53598.1 - 4.8e-15 55.4 0.2 6.4e-15 55.0 0.2 1.2 1 0 0 1 1 1 1 Elicitin TPR_12 PF13424.6 RLN53599.1 - 2.5e-05 24.5 7.2 0.005 17.1 0.1 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN53599.1 - 0.00027 20.8 0.4 0.28 11.4 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN53599.1 - 0.0091 15.8 0.0 0.22 11.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN53599.1 - 0.016 15.1 9.4 0.04 13.8 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 RLN53599.1 - 0.03 14.5 0.0 0.21 11.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Urb2 PF10441.9 RLN53599.1 - 0.061 13.3 0.0 0.24 11.3 0.0 1.9 1 1 0 1 1 1 0 Urb2/Npa2 family TPR_14 PF13428.6 RLN53599.1 - 5.5 8.1 12.9 19 6.4 0.1 5.3 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN53599.1 - 8.6 7.1 12.9 11 6.8 0.0 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat HAT PF02184.16 RLN53600.1 - 5.2e-24 83.9 65.5 9.5e-08 31.9 0.2 14.9 16 0 0 16 16 16 8 HAT (Half-A-TPR) repeat Suf PF05843.14 RLN53600.1 - 2.7e-16 60.4 25.6 5.1e-05 23.4 2.7 6.6 2 2 2 4 4 4 4 Suppressor of forked protein (Suf) TPR_14 PF13428.6 RLN53600.1 - 1.4e-14 53.5 41.2 0.0078 17.0 0.1 11.4 5 4 8 13 13 12 8 Tetratricopeptide repeat TPR_16 PF13432.6 RLN53600.1 - 1.7e-13 51.0 23.3 0.013 16.1 4.1 7.6 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 RLN53600.1 - 9.9e-12 45.2 6.3 0.11 13.1 2.1 6.4 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 RLN53600.1 - 4.5e-07 29.5 24.0 3.3 8.1 0.1 10.2 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN53600.1 - 2.4e-06 27.5 3.1 0.032 14.6 0.0 6.8 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN53600.1 - 0.00016 21.8 19.8 0.0042 17.2 0.1 6.5 6 2 0 7 7 7 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 RLN53600.1 - 0.00018 21.5 26.1 0.026 14.5 0.7 7.6 6 3 1 7 7 7 1 Mad3/BUB1 homology region 1 U3_assoc_6 PF08640.11 RLN53600.1 - 0.19 11.8 0.2 0.19 11.8 0.2 6.5 4 3 4 8 8 8 0 U3 small nucleolar RNA-associated protein 6 TPR_8 PF13181.6 RLN53600.1 - 3.3 8.1 17.6 3.9 7.9 0.1 7.8 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_7 PF13176.6 RLN53600.1 - 6.9 6.9 14.0 11 6.3 0.4 6.4 10 0 0 10 10 8 0 Tetratricopeptide repeat Elicitin PF00964.17 RLN53601.1 - 1.1e-17 63.9 5.3 1.1e-17 63.9 5.3 1.5 2 0 0 2 2 2 1 Elicitin Nuf2 PF03800.14 RLN53601.1 - 0.14 12.3 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Nuf2 family Elicitin PF00964.17 RLN53602.1 - 2.6e-27 94.7 0.8 8.2e-13 48.3 0.2 2.2 2 0 0 2 2 2 2 Elicitin PLAC8 PF04749.17 RLN53603.1 - 0.047 14.7 8.0 0.082 13.9 8.0 1.5 1 1 0 1 1 1 0 PLAC8 family CheR PF01739.18 RLN53614.1 - 0.026 14.0 0.0 0.036 13.5 0.0 1.1 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain GDP_Man_Dehyd PF16363.5 RLN53615.1 - 7.5e-72 242.5 0.0 3.5e-65 220.6 0.0 2.0 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RLN53615.1 - 3.6e-54 183.8 0.0 1.5e-53 181.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 RLN53615.1 - 2e-20 73.2 0.0 6.1e-16 58.4 0.0 3.1 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 RLN53615.1 - 1.2e-17 63.9 0.0 8.2e-13 48.0 0.0 2.1 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 RLN53615.1 - 4.8e-17 62.0 0.0 1.4e-13 50.7 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 RLN53615.1 - 3.6e-16 59.1 0.0 5.1e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 RLN53615.1 - 0.028 14.3 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H-binding DUF5090 PF17009.5 RLN53616.1 - 0.18 11.7 3.6 0.27 11.2 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Shikimate_dh_N PF08501.11 RLN53644.1 - 1.6e-20 73.2 0.0 2.9e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 RLN53644.1 - 3.1e-10 40.3 0.0 4.6e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 RLN53644.1 - 0.00032 20.4 0.1 0.00032 20.4 0.1 2.1 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain SIS_2 PF13580.6 RLN53644.1 - 0.002 18.2 0.1 0.0037 17.3 0.1 1.3 1 0 0 1 1 1 1 SIS domain F420_oxidored PF03807.17 RLN53644.1 - 0.047 14.3 0.1 0.092 13.3 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CoA_binding PF02629.19 RLN53644.1 - 0.1 13.3 0.0 0.27 11.9 0.0 1.7 1 0 0 1 1 1 0 CoA binding domain Pyr_redox_2 PF07992.14 RLN53644.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Aph-1 PF06105.12 RLN53645.1 - 5.7e-43 147.0 15.0 7.5e-43 146.6 15.0 1.0 1 0 0 1 1 1 1 Aph-1 protein YadA_anchor PF03895.15 RLN53645.1 - 0.23 11.6 7.1 0.64 10.2 0.2 2.5 2 0 0 2 2 2 0 YadA-like membrane anchor domain E1-E2_ATPase PF00122.20 RLN53647.1 - 6.2e-47 159.4 1.6 1.8e-46 158.0 1.6 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 RLN53647.1 - 3.6e-17 63.4 0.1 1.4e-16 61.5 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RLN53647.1 - 1.2e-14 53.8 0.1 2.4e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RLN53647.1 - 0.00039 20.2 0.8 0.00068 19.4 0.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN53647.1 - 0.01 15.9 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Phage_holin_Dp1 PF16938.5 RLN53647.1 - 0.35 11.1 2.6 7.1 6.9 1.2 2.6 2 0 0 2 2 2 0 Putative phage holin Dp-1 PAM2 PF07145.15 RLN53648.1 - 0.12 12.1 1.9 0.36 10.6 1.9 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region DraK_HK_N PF18092.1 RLN53649.1 - 1.1 9.7 5.3 3.7 8.1 5.3 1.8 1 1 0 1 1 1 0 DraK Histidine Kinase N-terminal domain EPSP_synthase PF00275.20 RLN53650.1 - 5.7e-124 414.0 0.2 8.8e-124 413.4 0.2 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 RLN53650.1 - 1.5e-94 316.0 1.0 2e-94 315.7 0.1 1.7 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 RLN53650.1 - 1.5e-44 152.9 0.0 2.7e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 RLN53650.1 - 9.4e-27 94.1 0.0 2.6e-25 89.4 0.0 2.8 2 0 0 2 2 2 1 Shikimate kinase Fe-ADH_2 PF13685.6 RLN53650.1 - 7.7e-12 45.4 0.5 1.8e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase AAA_16 PF13191.6 RLN53650.1 - 0.00063 20.2 0.1 0.0049 17.3 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 RLN53650.1 - 0.00065 19.9 0.0 0.0079 16.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain Fe-ADH PF00465.19 RLN53650.1 - 0.0023 16.8 0.3 0.0064 15.4 0.1 1.9 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase AAA_18 PF13238.6 RLN53650.1 - 0.065 13.8 0.0 1.2 9.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 RLN53650.1 - 0.08 12.1 0.4 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 RLN53650.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain FAR1 PF03101.15 RLN53651.1 - 0.085 13.6 0.3 0.19 12.5 0.3 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain DUF5575 PF17738.1 RLN53651.1 - 0.12 11.3 4.1 1 8.3 4.1 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5575) Osteoregulin PF07175.11 RLN53651.1 - 0.12 12.5 0.2 0.34 11.1 0.1 1.8 2 0 0 2 2 2 0 Osteoregulin RSN1_7TM PF02714.15 RLN53657.1 - 1.9e-21 76.6 13.3 6.9e-21 74.8 8.1 2.3 1 1 1 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 RLN53657.1 - 6.3e-13 48.8 0.5 3e-12 46.6 0.5 2.3 1 1 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 RLN53657.1 - 0.025 14.8 0.6 1.2 9.3 0.6 2.9 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter CRC_subunit PF08624.10 RLN53657.1 - 0.23 11.9 0.1 2.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Chromatin remodelling complex Rsc7/Swp82 subunit DUF5345 PF17280.2 RLN53658.1 - 0.025 14.6 0.0 0.085 12.8 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5345) ABC_tran PF00005.27 RLN53666.1 - 2.1e-06 28.3 0.2 2.9e-06 27.8 0.2 1.3 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 RLN53666.1 - 0.0017 17.7 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 RLN53666.1 - 0.0035 17.7 0.1 0.0056 17.1 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 RLN53666.1 - 0.0051 16.5 0.3 0.0099 15.6 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN53666.1 - 0.0077 16.1 0.1 0.016 15.1 0.1 1.5 1 1 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 RLN53666.1 - 0.019 15.3 0.0 0.035 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RLN53666.1 - 0.039 13.5 0.1 0.066 12.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 RLN53666.1 - 0.058 13.4 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MCM PF00493.23 RLN53666.1 - 0.082 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain DUF815 PF05673.13 RLN53666.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Ploopntkinase3 PF18751.1 RLN53666.1 - 0.14 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 NACHT PF05729.12 RLN53666.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 RLN53666.1 - 0.17 11.4 0.1 0.25 10.8 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_ATPase PF09818.9 RLN53666.1 - 0.2 10.4 0.2 0.29 9.9 0.2 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class MCU PF04678.13 RLN53671.1 - 6.7e-25 88.2 1.1 2.5e-24 86.3 0.8 2.0 1 1 1 2 2 2 1 Mitochondrial calcium uniporter MIP-T3_C PF17749.1 RLN53671.1 - 0.053 13.5 0.3 0.053 13.5 0.3 1.9 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region DUF3287 PF11690.8 RLN53671.1 - 0.087 12.6 0.8 0.37 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Prefoldin_2 PF01920.20 RLN53671.1 - 0.2 11.7 4.1 0.31 11.0 1.2 2.2 2 0 0 2 2 2 0 Prefoldin subunit Snapin_Pallidin PF14712.6 RLN53671.1 - 0.38 11.2 3.2 0.8 10.2 1.1 2.3 2 0 0 2 2 2 0 Snapin/Pallidin DivIC PF04977.15 RLN53671.1 - 0.56 10.0 2.4 1.5 8.6 0.1 2.3 2 0 0 2 2 2 0 Septum formation initiator Unstab_antitox PF09720.10 RLN53671.1 - 0.91 9.6 5.1 0.93 9.6 0.3 2.9 3 0 0 3 3 3 0 Putative addiction module component DUF5082 PF16888.5 RLN53671.1 - 1.1 9.6 3.6 9.2 6.6 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Sep15_SelM PF08806.11 RLN53672.1 - 6.4e-18 64.7 2.2 1.3e-14 54.1 0.0 2.8 3 0 0 3 3 3 2 Sep15/SelM redox domain Nup96 PF12110.8 RLN53672.1 - 0.00025 20.3 0.5 0.00037 19.7 0.5 1.3 1 0 0 1 1 1 1 Nuclear protein 96 SUV3_C PF12513.8 RLN53674.1 - 4.7e-13 48.8 0.5 1.2e-12 47.6 0.5 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 RLN53674.1 - 1.6e-11 43.9 0.2 3.4e-11 42.8 0.2 1.6 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 RLN53674.1 - 1e-10 41.9 0.0 2.5e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_N PF18114.1 RLN53674.1 - 0.021 14.9 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 Suv3 helical N-terminal domain Exo_endo_phos PF03372.23 RLN53675.1 - 2.4e-05 24.0 0.0 0.00027 20.5 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Benyvirus_P25 PF05744.11 RLN53675.1 - 0.056 12.7 0.1 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 Benyvirus P25/P26 protein Claudin_3 PF06653.11 RLN53675.1 - 0.071 13.1 6.6 0.25 11.3 1.5 2.3 2 0 0 2 2 2 0 Tight junction protein, Claudin-like Claudin_2 PF13903.6 RLN53675.1 - 2.6 7.8 14.3 1.3 8.8 8.5 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction UPRTase PF14681.6 RLN53676.1 - 1.2e-09 37.9 0.0 2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase V-ATPase_G PF03179.15 RLN53677.1 - 2e-21 76.5 9.6 2.3e-21 76.3 9.6 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 RLN53677.1 - 0.0015 18.0 8.9 0.0015 18.0 8.9 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3552) EcoR124_C PF12008.8 RLN53677.1 - 0.031 13.9 1.9 0.036 13.7 1.9 1.0 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal zf-CCCH_7 PF18586.1 RLN53677.1 - 0.13 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Macoilin PF09726.9 RLN53677.1 - 0.24 9.9 4.8 0.28 9.7 4.8 1.0 1 0 0 1 1 1 0 Macoilin family NAM-associated PF14303.6 RLN53677.1 - 1.3 9.7 8.9 2 9.1 8.9 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Mt_ATP-synt_D PF05873.12 RLN53677.1 - 2.4 8.0 7.3 3.5 7.5 4.4 1.9 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF1515 PF07439.11 RLN53720.1 - 3.4 7.7 4.9 2.3 8.3 2.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Glyco_transf_22 PF03901.17 RLN53721.1 - 3.5e-51 174.7 14.2 4.7e-51 174.3 14.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family GIT_CC PF16559.5 RLN53722.1 - 0.013 15.4 20.3 0.096 12.6 3.5 4.0 2 2 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3584 PF12128.8 RLN53722.1 - 0.038 11.5 25.6 0.051 11.1 25.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Filament PF00038.21 RLN53722.1 - 0.056 13.0 26.3 0.27 10.8 15.6 2.4 1 1 1 2 2 2 0 Intermediate filament protein DUF1635 PF07795.11 RLN53722.1 - 0.83 9.5 23.9 0.049 13.5 5.7 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1635) CENP-F_leu_zip PF10473.9 RLN53722.1 - 1.9 8.5 25.7 0.45 10.5 8.2 2.6 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 RLN53722.1 - 2.8 8.0 29.7 4.6 7.3 16.6 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 RLN53722.1 - 3.3 5.5 23.7 5.7 4.7 9.4 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family IQ PF00612.27 RLN53729.1 - 5.8e-11 41.2 17.6 0.53 10.2 0.1 7.5 7 0 0 7 7 7 6 IQ calmodulin-binding motif Pyridox_ox_2 PF12900.7 RLN53729.1 - 0.036 14.1 2.4 3.6 7.6 0.3 3.3 1 1 2 3 3 3 0 Pyridoxamine 5'-phosphate oxidase Zot PF05707.12 RLN53729.1 - 0.094 12.3 4.0 2 8.0 0.2 2.8 1 1 1 3 3 3 0 Zonular occludens toxin (Zot) PAP2 PF01569.21 RLN53730.1 - 7.5e-22 77.6 7.9 1.5e-21 76.6 7.9 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 RLN53730.1 - 5.7e-05 23.6 3.0 5.7e-05 23.6 3.0 2.2 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2_3 PF14378.6 RLN53730.1 - 0.00012 21.8 14.6 0.0029 17.3 14.5 2.7 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 RLN53730.1 - 0.16 12.1 0.5 4.5 7.4 0.2 2.2 1 1 1 2 2 2 0 Divergent PAP2 family DUF3522 PF12036.8 RLN53732.1 - 1.1e-25 91.1 0.2 4.6e-21 76.0 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3522) Ceramidase PF05875.12 RLN53732.1 - 0.083 12.3 0.2 0.19 11.1 0.0 1.6 2 0 0 2 2 2 0 Ceramidase Pkinase PF00069.25 RLN53733.1 - 8.3e-55 186.0 0.0 2.1e-50 171.6 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN53733.1 - 2.8e-25 89.1 0.0 3.9e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN53733.1 - 2.4e-05 23.8 0.0 3.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RLN53733.1 - 2.6e-05 23.2 0.0 3.4e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN53733.1 - 8.6e-05 22.6 3.4 0.0004 20.4 3.4 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN53733.1 - 0.0018 17.7 2.0 0.004 16.5 2.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TAP42 PF04177.12 RLN53733.1 - 0.055 12.6 1.1 0.076 12.1 1.1 1.1 1 0 0 1 1 1 0 TAP42-like family DUF423 PF04241.15 RLN53734.1 - 0.17 12.1 1.4 2.9 8.1 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF423) DUF1295 PF06966.12 RLN53744.1 - 6.9e-60 202.5 1.4 9.6e-60 202.0 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 RLN53744.1 - 8.6e-08 32.3 0.0 1.8e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 RLN53744.1 - 9.3e-05 22.8 0.3 0.00039 20.8 0.1 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 RLN53744.1 - 0.0057 17.0 0.0 0.0057 17.0 0.0 2.9 3 1 0 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 RLN53744.1 - 0.051 12.3 0.2 0.24 10.1 0.2 2.0 1 1 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family TipAS PF07739.13 RLN53744.1 - 0.058 13.9 0.6 0.12 13.0 0.2 1.7 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain IBR PF01485.21 RLN53745.1 - 6.6e-21 74.3 23.3 3.8e-16 59.0 4.0 3.2 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain Pkinase_Tyr PF07714.17 RLN53747.1 - 6.8e-08 32.1 0.0 9e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_1 PF00536.30 RLN53747.1 - 8.5e-07 29.3 0.0 1.6e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RLN53747.1 - 4.6e-05 23.5 0.0 8.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 RLN53747.1 - 0.00011 22.7 1.0 0.00024 21.6 1.0 1.6 1 0 0 1 1 1 1 PH domain Pkinase PF00069.25 RLN53747.1 - 0.00011 21.7 0.0 0.00025 20.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain FAM176 PF14851.6 RLN53747.1 - 3.4 7.3 5.1 5.4 6.7 4.1 1.8 2 0 0 2 2 2 0 FAM176 family SlyX PF04102.12 RLN53748.1 - 0.11 13.1 0.5 0.35 11.5 0.0 2.0 2 0 0 2 2 2 0 SlyX PspA_IM30 PF04012.12 RLN53749.1 - 0.003 17.2 2.9 0.0048 16.5 2.9 1.2 1 0 0 1 1 1 1 PspA/IM30 family DUF641 PF04859.12 RLN53749.1 - 0.06 13.7 2.5 0.21 11.9 0.5 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) HMMR_N PF15905.5 RLN53749.1 - 0.068 12.6 1.6 0.098 12.1 1.6 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF3450 PF11932.8 RLN53749.1 - 0.077 12.3 5.7 0.13 11.6 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CorA PF01544.18 RLN53749.1 - 0.14 11.4 1.8 0.26 10.5 1.8 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF948 PF06103.11 RLN53749.1 - 1.3 9.4 3.3 1.7 8.9 1.5 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Cep57_CLD_2 PF14197.6 RLN53749.1 - 1.4 9.0 4.6 5.5 7.2 0.5 2.8 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 Flagellin_N PF00669.20 RLN53749.1 - 1.7 8.8 8.0 5.8 7.0 2.5 2.2 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region SlyX PF04102.12 RLN53749.1 - 5.5 7.7 7.4 3.6 8.3 2.8 2.4 1 1 1 2 2 2 0 SlyX Tannase PF07519.11 RLN53751.1 - 3.4e-128 428.5 0.0 5.3e-128 427.9 0.0 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 RLN53751.1 - 0.0012 18.4 0.2 1.3 8.4 0.3 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 RLN53753.1 - 7.4e-98 328.6 0.8 2.4e-97 326.9 0.8 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RLN53753.1 - 0.0003 20.7 0.0 0.0003 20.7 0.0 2.4 3 0 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN53753.1 - 0.0059 16.1 0.1 0.0059 16.1 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Ribo_biogen_C PF04034.13 RLN53754.1 - 7.1e-51 171.2 0.0 1e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 RLN53754.1 - 1.7e-09 37.3 0.4 2.8e-09 36.6 0.4 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DNA_pol_phi PF04931.13 RLN53754.1 - 6.7 4.7 16.0 9.8 4.1 16.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Mito_carr PF00153.27 RLN53755.1 - 3.9e-67 222.2 7.6 1.8e-26 91.9 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 RLN53755.1 - 0.074 12.2 3.9 0.61 9.2 0.0 2.9 3 1 0 3 3 3 0 Gammaproteobacterial serine protease DUF1258 PF06869.12 RLN53756.1 - 0.056 12.9 0.1 0.072 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) HIG_1_N PF04588.13 RLN53770.1 - 5.6e-18 64.9 2.5 1.2e-17 63.9 2.5 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Myosin_head PF00063.21 RLN53770.1 - 0.002 16.4 0.0 0.0024 16.2 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) COX15-CtaA PF02628.15 RLN53770.1 - 0.031 13.3 0.1 0.041 12.9 0.1 1.1 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein Yip1 PF04893.17 RLN53770.1 - 0.063 13.0 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 Yip1 domain SNARE PF05739.19 RLN53771.1 - 1.3e-11 44.3 0.1 2.9e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 RLN53771.1 - 5.4e-07 29.5 3.5 0.0011 18.6 0.1 2.1 2 0 0 2 2 2 2 Syntaxin Baculo_PEP_C PF04513.12 RLN53771.1 - 0.011 15.8 2.4 0.96 9.5 0.4 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Myosin_head PF00063.21 RLN53772.1 - 8.5e-22 77.2 0.0 4.6e-21 74.7 0.0 1.7 1 1 1 2 2 2 2 Myosin head (motor domain) LRR_4 PF12799.7 RLN53773.1 - 0.00084 19.7 0.8 6.5 7.3 0.1 4.2 4 2 0 4 4 4 2 Leucine Rich repeats (2 copies) GHMP_kinases_N PF00288.26 RLN53774.1 - 0.086 13.1 0.5 13 6.2 0.4 2.2 2 0 0 2 2 2 0 GHMP kinases N terminal domain Mito_carr PF00153.27 RLN53775.1 - 4e-56 186.9 0.3 1.7e-21 75.9 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L19e PF01280.20 RLN53776.1 - 9.1e-61 204.1 9.5 9.1e-61 204.1 9.5 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e DBD_Tnp_Hermes PF10683.9 RLN53777.1 - 0.0036 16.9 0.0 0.0083 15.8 0.0 1.6 1 0 0 1 1 1 1 Hermes transposase DNA-binding domain RWP-RK PF02042.15 RLN53779.1 - 4.5e-22 77.8 0.3 7.4e-22 77.1 0.3 1.4 1 0 0 1 1 1 1 RWP-RK domain SAICAR_synt PF01259.18 RLN53780.1 - 2.3e-78 263.3 0.0 3.2e-78 262.8 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Mg_trans_NIPA PF05653.14 RLN53781.1 - 1e-40 139.7 10.9 5.8e-40 137.2 10.9 1.8 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 RLN53781.1 - 1.5e-05 25.2 3.0 1.5e-05 25.2 3.0 3.3 2 2 1 3 3 3 1 EamA-like transporter family TMEM234 PF10639.9 RLN53781.1 - 0.00035 20.6 1.4 0.00043 20.3 0.2 1.8 2 0 0 2 2 2 1 Putative transmembrane family 234 Polysacc_synt_C PF14667.6 RLN53781.1 - 0.074 13.1 0.3 0.074 13.1 0.3 2.8 2 1 1 3 3 3 0 Polysaccharide biosynthesis C-terminal domain PACT_coil_coil PF10495.9 RLN53781.1 - 0.15 12.7 0.5 0.32 11.6 0.5 1.5 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein DEC-1_N PF04625.13 RLN53782.1 - 0.2 10.6 6.1 0.38 9.7 5.5 1.6 1 1 1 2 2 2 0 DEC-1 protein, N-terminal region Lactamase_B_4 PF13691.6 RLN53804.1 - 0.00042 19.9 0.0 0.0035 17.0 0.0 2.2 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 RLN53804.1 - 0.0011 18.5 0.6 0.15 11.6 0.0 2.4 1 1 1 2 2 2 2 Beta-lactamase superfamily domain PDEase_II PF02112.15 RLN53804.1 - 0.16 11.0 0.2 0.28 10.3 0.0 1.5 2 0 0 2 2 2 0 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 RLN53804.1 - 0.32 11.0 1.7 0.6 10.1 1.7 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily SMC_N PF02463.19 RLN53805.1 - 6e-21 74.9 0.0 6.2e-13 48.7 0.0 2.9 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RLN53805.1 - 2.3e-12 47.8 24.7 4e-11 43.8 15.0 3.9 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 RLN53805.1 - 3.4e-06 27.0 0.9 0.0002 21.2 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 RLN53805.1 - 0.00032 20.4 0.0 0.00069 19.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_11 PF13086.6 RLN53805.1 - 0.013 15.3 0.4 0.013 15.3 0.4 2.6 2 1 0 2 2 2 0 AAA domain AAA_27 PF13514.6 RLN53805.1 - 0.014 15.0 0.0 0.04 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RLN53805.1 - 0.018 14.8 0.4 5.9 6.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 RLN53805.1 - 0.047 13.5 2.9 0.16 11.7 0.2 2.8 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 RLN53805.1 - 0.056 13.0 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 RLN53805.1 - 0.28 11.7 4.7 0.84 10.2 2.4 3.1 2 2 0 2 2 2 0 ABC transporter Methyltr_RsmB-F PF01189.17 RLN53807.1 - 1.5e-08 34.5 0.0 2.6e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 RLN53807.1 - 1.7e-08 34.9 0.0 4.8e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF CDC27 PF09507.10 RLN53807.1 - 0.18 11.1 24.1 0.24 10.8 24.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SDA1 PF05285.12 RLN53807.1 - 0.55 9.6 36.2 0.78 9.1 36.2 1.1 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 RLN53807.1 - 3.7 7.2 31.7 6.5 6.4 31.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein eIF-3c_N PF05470.12 RLN53807.1 - 5.2 5.2 16.2 7.6 4.7 16.2 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.14 RLN53807.1 - 8.9 4.5 21.8 13 3.9 21.8 1.4 1 0 0 1 1 1 0 CDC45-like protein PK_C PF02887.16 RLN53808.1 - 3.7e-06 27.2 0.1 4.3e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain PK PF00224.21 RLN53809.1 - 6.8e-94 314.6 2.2 7.8e-91 304.5 1.0 2.1 1 1 1 2 2 2 2 Pyruvate kinase, barrel domain PK_C PF02887.16 RLN53809.1 - 7.7e-15 55.2 0.5 3.6e-14 53.0 0.4 2.2 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 RLN53809.1 - 0.00022 20.4 0.5 0.0006 19.0 0.2 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family SET PF00856.28 RLN53810.1 - 0.00011 22.7 0.0 0.00064 20.1 0.0 2.2 1 1 0 1 1 1 1 SET domain Ribosomal_L27 PF01016.19 RLN53811.1 - 1.1e-30 105.5 4.5 7.6e-30 102.8 4.5 1.9 1 1 0 1 1 1 1 Ribosomal L27 protein zf-RING_UBOX PF13445.6 RLN53811.1 - 0.18 11.8 0.1 0.31 11.1 0.1 1.4 1 0 0 1 1 1 0 RING-type zinc-finger Pkinase PF00069.25 RLN53813.1 - 1.1e-61 208.5 0.0 1.5e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN53813.1 - 2.8e-31 108.8 0.0 4.2e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN53813.1 - 2.4e-07 30.4 0.0 4.3e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like PH PF00169.29 RLN53813.1 - 9.1e-07 29.3 0.1 2.3e-06 28.1 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN53813.1 - 9.8e-06 26.0 1.3 5.6e-05 23.5 1.3 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain APH PF01636.23 RLN53813.1 - 0.0011 18.9 0.2 0.0038 17.2 0.2 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN53813.1 - 0.025 13.5 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain PH_8 PF15409.6 RLN53813.1 - 0.028 14.7 0.7 0.15 12.4 0.5 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Pkinase_fungal PF17667.1 RLN53813.1 - 0.041 12.7 0.0 0.09 11.5 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 RLN53813.1 - 0.085 11.9 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PH_13 PF16652.5 RLN53813.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Adipokin_hormo PF06377.11 RLN53813.1 - 0.15 12.4 0.0 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 Adipokinetic hormone Ribosomal_S15 PF00312.22 RLN53830.1 - 0.039 14.2 0.6 0.089 13.0 0.6 1.5 1 0 0 1 1 1 0 Ribosomal protein S15 FAM184 PF15665.5 RLN53830.1 - 0.55 10.0 7.3 0.18 11.6 3.0 1.9 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B TPR_MLP1_2 PF07926.12 RLN53830.1 - 1.5 8.8 12.8 3 7.9 12.8 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein MYO10_CC PF16735.5 RLN53830.1 - 5.2 7.3 12.5 7.7 6.7 2.9 3.0 2 0 0 2 2 2 0 Unconventional myosin-X coiled coil domain DUF1192 PF06698.11 RLN53830.1 - 5.5 7.1 8.5 23 5.1 0.9 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) FlxA PF14282.6 RLN53830.1 - 7.1 6.7 12.4 7.7 6.6 4.1 2.9 2 0 0 2 2 2 0 FlxA-like protein MULE PF10551.9 RLN53846.1 - 6.7e-07 29.6 0.0 4e-06 27.1 0.0 2.3 1 0 0 1 1 1 1 MULE transposase domain PriCT_2 PF08707.11 RLN53846.1 - 0.0029 17.9 0.0 0.077 13.4 0.0 2.5 2 0 0 2 2 2 1 Primase C terminal 2 (PriCT-2) Synaptobrevin PF00957.21 RLN53850.1 - 3e-25 87.8 2.9 6.2e-25 86.8 2.9 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 RLN53850.1 - 3.8e-06 26.9 0.0 9.1e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain ODV-E18 PF10717.9 RLN53850.1 - 0.028 14.3 1.2 0.063 13.1 1.2 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Aldo_ket_red PF00248.21 RLN53850.1 - 0.12 11.6 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Aldo/keto reductase family CRIC_ras_sig PF10534.9 RLN53851.1 - 0.099 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Connector enhancer of kinase suppressor of ras ADH_N PF08240.12 RLN53852.1 - 2.2e-23 82.2 1.5 2.2e-23 82.2 1.5 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN53852.1 - 3.6e-15 56.1 0.0 5.9e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN53852.1 - 0.00039 19.8 0.0 0.00067 19.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 RLN53852.1 - 0.0012 19.9 0.0 0.0021 19.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 RLN53852.1 - 0.03 13.6 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HEAT PF02985.22 RLN53853.1 - 1.6e-06 27.9 6.1 0.15 12.3 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 RLN53853.1 - 1e-05 25.8 3.5 0.0012 19.2 0.4 4.7 3 1 2 5 5 5 2 HEAT repeats Cnd1 PF12717.7 RLN53853.1 - 0.00011 22.2 0.8 0.0066 16.5 0.1 3.3 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 RLN53853.1 - 0.0011 19.1 0.1 0.031 14.4 0.0 2.9 2 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Cohesin_HEAT PF12765.7 RLN53853.1 - 0.022 15.1 2.0 7.7 6.9 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion CLASP_N PF12348.8 RLN53853.1 - 0.1 12.1 0.0 0.33 10.5 0.0 1.8 1 0 0 1 1 1 0 CLASP N terminal HEAT_EZ PF13513.6 RLN53853.1 - 0.59 10.7 0.0 0.59 10.7 0.0 3.4 5 0 0 5 5 5 0 HEAT-like repeat Copine PF07002.16 RLN53854.1 - 2.1e-38 132.0 0.0 3.8e-25 88.6 0.0 2.0 2 0 0 2 2 2 2 Copine vWA-TerF-like PF10138.9 RLN53854.1 - 0.00019 21.6 0.0 0.49 10.5 0.1 2.1 2 0 0 2 2 2 2 vWA found in TerF C terminus WD40 PF00400.32 RLN53867.1 - 1e-23 83.1 28.5 0.0079 17.0 0.0 13.9 13 1 0 13 13 13 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN53867.1 - 1.7e-06 28.3 0.1 5.9 7.3 0.0 7.3 7 2 2 9 9 9 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN53867.1 - 5.4e-05 22.0 0.1 0.07 11.8 0.0 3.8 4 0 0 4 4 4 2 Nucleoporin Nup120/160 HZS_alpha PF18582.1 RLN53867.1 - 0.017 15.6 0.0 1 9.9 0.0 3.0 2 0 0 2 2 2 0 Hydrazine synthase alpha subunit middle domain Lgl_C PF08596.10 RLN53867.1 - 0.11 11.1 0.3 3 6.4 0.0 3.0 3 0 0 3 3 3 0 Lethal giant larvae(Lgl) like, C-terminal Pro_isomerase PF00160.21 RLN53868.1 - 1.6e-41 142.2 0.0 1.9e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD KH_8 PF17903.1 RLN53869.1 - 3.5e-05 23.8 0.0 9.2e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 RLN53869.1 - 0.0081 16.0 0.1 0.019 14.8 0.1 1.6 1 0 0 1 1 1 1 KH domain TMEM43 PF07787.12 RLN53870.1 - 7.3e-58 195.9 0.0 1.4e-57 194.9 0.0 1.4 2 0 0 2 2 2 1 Transmembrane protein 43 AAA_26 PF13500.6 RLN53872.1 - 7.6e-23 81.4 0.0 1.2e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain PTEN_C2 PF10409.9 RLN53873.1 - 3.1e-18 65.8 0.0 4e-17 62.2 0.0 2.2 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 RLN53873.1 - 0.00013 21.7 0.0 0.0003 20.6 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 RLN53873.1 - 0.017 15.1 0.0 0.017 15.1 0.0 1.9 3 0 0 3 3 3 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 RLN53873.1 - 0.045 13.3 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase zf-CCCH_4 PF18044.1 RLN53874.1 - 7.6e-11 41.6 3.8 1.2e-10 41.0 3.8 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 RLN53874.1 - 9.4e-09 35.0 6.5 1.5e-08 34.4 6.5 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 RLN53874.1 - 2.1e-07 30.7 4.2 3.3e-07 30.1 4.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 RLN53874.1 - 0.0035 18.0 0.7 0.0055 17.4 0.7 1.2 1 0 0 1 1 1 1 Torus domain zf-CCCH_3 PF15663.5 RLN53874.1 - 0.019 15.2 0.7 0.028 14.6 0.7 1.2 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 RLN53874.1 - 0.022 15.2 5.8 0.042 14.3 5.8 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Serglycin PF04360.12 RLN53874.1 - 2.9 7.8 5.8 3.9 7.4 5.8 1.2 1 0 0 1 1 1 0 Serglycin HAGH_C PF16123.5 RLN53875.1 - 7.1e-26 90.5 0.0 1.1e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 RLN53875.1 - 0.004 17.2 0.6 0.022 14.8 0.6 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily SET PF00856.28 RLN53876.1 - 5.6e-13 49.6 0.0 9.1e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 RLN53876.1 - 0.00019 21.4 11.3 0.00019 21.4 11.3 3.4 3 1 1 4 4 4 1 MYND finger zf-Mss51 PF13824.6 RLN53876.1 - 0.013 15.6 13.0 2 8.6 3.3 3.9 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Foie-gras_1 PF11817.8 RLN53878.1 - 4.9e-25 88.6 0.0 8.9e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun-like PF12742.7 RLN53878.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking TRAPPC10 PF12584.8 RLN53878.1 - 0.016 14.9 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 Glyco_hydro_30 PF02055.16 RLN53895.1 - 1e-12 47.7 0.0 1.4e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain GATase_3 PF07685.14 RLN53895.1 - 0.098 12.2 0.0 0.37 10.4 0.0 1.7 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain Glyco_hydro_30 PF02055.16 RLN53896.1 - 2.4e-83 280.0 0.2 3.6e-83 279.4 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Ricin_B_lectin PF00652.22 RLN53896.1 - 6.5e-11 42.6 3.3 1.2e-06 28.8 0.9 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Glyco_hydro_30C PF17189.4 RLN53896.1 - 2.8e-09 37.0 0.1 6.8e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 RLN53896.1 - 8.3e-08 31.8 0.0 1.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 RLN53896.1 - 6.1e-05 22.8 0.0 0.00023 20.9 0.0 1.8 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 RicinB_lectin_2 PF14200.6 RLN53896.1 - 0.002 18.8 0.4 0.0052 17.5 0.4 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like FAD_binding_7 PF03441.14 RLN53904.1 - 2.3e-76 255.8 1.2 3.6e-76 255.2 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 RLN53904.1 - 5.8e-37 127.2 0.7 1.4e-36 126.0 0.7 1.6 1 1 0 1 1 1 1 DNA photolyase FAM176 PF14851.6 RLN53904.1 - 0.58 9.8 4.6 1.1 8.9 4.6 1.4 1 0 0 1 1 1 0 FAM176 family RNA_pol_3_Rpc31 PF11705.8 RLN53904.1 - 0.67 10.2 11.1 1.9 8.7 11.1 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Radial_spoke PF04712.12 RLN53904.1 - 6.9 5.5 11.4 11 4.8 11.4 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein SDA1 PF05285.12 RLN53905.1 - 0.0093 15.4 16.2 0.012 15.1 16.2 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 RLN53905.1 - 0.034 12.4 16.4 0.042 12.1 16.4 1.0 1 0 0 1 1 1 0 Nop14-like family Apt1 PF10351.9 RLN53905.1 - 0.24 10.2 7.8 0.26 10.1 7.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain BUD22 PF09073.10 RLN53905.1 - 0.34 10.2 23.3 0.47 9.7 23.3 1.1 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.9 RLN53905.1 - 0.47 9.6 22.1 0.65 9.1 22.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SAPS PF04499.15 RLN53905.1 - 1.7 7.3 3.3 2 7.1 3.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SpoIIIAH PF12685.7 RLN53905.1 - 2.1 8.1 7.7 3.6 7.4 7.7 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF515 PF04415.12 RLN53905.1 - 2.7 6.3 7.1 4.8 5.4 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) CDC45 PF02724.14 RLN53905.1 - 2.9 6.1 15.2 3.9 5.7 15.2 1.1 1 0 0 1 1 1 0 CDC45-like protein CNDH2_C PF16858.5 RLN53905.1 - 8.9 6.1 9.3 13 5.6 9.3 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term zf-RING_2 PF13639.6 RLN53906.1 - 3.1e-11 43.4 10.7 5.6e-11 42.6 10.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RLN53906.1 - 1.7e-09 37.8 7.9 3.7e-09 36.7 7.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 RLN53906.1 - 2.5e-08 33.6 5.6 3.6e-08 33.1 5.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN53906.1 - 1.3e-07 31.3 10.6 2.3e-07 30.5 10.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN53906.1 - 2.4e-07 30.3 7.6 6.1e-07 29.1 7.6 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 RLN53906.1 - 3.4e-07 30.0 10.0 5.9e-07 29.2 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN53906.1 - 1.9e-05 24.6 11.2 4.6e-05 23.4 11.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN53906.1 - 0.00019 21.3 8.6 0.0003 20.7 8.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 RLN53906.1 - 0.00034 20.6 3.5 0.00078 19.5 3.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 RLN53906.1 - 0.0017 18.2 9.3 0.0028 17.5 9.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 RLN53906.1 - 0.051 13.2 7.9 0.098 12.3 7.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 RLN53906.1 - 0.39 10.9 8.0 1 9.5 8.0 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 RLN53906.1 - 0.5 10.6 12.1 0.23 11.6 9.3 2.0 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 RLN53906.1 - 1 9.6 6.7 4.4 7.6 6.8 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain S1 PF00575.23 RLN53907.1 - 2.7e-31 107.7 18.1 8.2e-08 32.5 0.0 8.7 8 1 0 8 8 8 6 S1 RNA binding domain PCB_OB PF17092.5 RLN53907.1 - 1.2 9.9 9.9 32 5.3 0.0 6.1 5 2 0 5 5 5 0 Penicillin-binding protein OB-like domain Anoctamin PF04547.12 RLN53908.1 - 4e-84 283.0 10.1 5.1e-84 282.7 10.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Ank_2 PF12796.7 RLN53908.1 - 1.6e-15 57.4 0.2 0.00065 20.2 0.0 5.1 4 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 RLN53908.1 - 3.3e-07 30.5 6.0 3 8.4 0.0 6.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 RLN53908.1 - 1.8e-06 27.8 1.2 12 6.8 0.0 5.7 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 RLN53908.1 - 9.6e-06 26.1 3.6 0.53 10.9 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN53908.1 - 0.003 17.8 6.1 6.8 7.1 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeats (many copies) FYVE_2 PF02318.16 RLN53908.1 - 0.12 12.6 4.0 0.34 11.1 1.1 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger Anoct_dimer PF16178.5 RLN53908.1 - 0.17 11.6 1.5 0.84 9.3 0.1 2.5 2 1 1 3 3 3 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin zf-rbx1 PF12678.7 RLN53909.1 - 1.6e-09 37.9 2.6 4.5e-09 36.5 2.6 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 RLN53909.1 - 4.8e-09 36.4 7.6 4.8e-09 36.4 7.6 2.5 2 2 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 RLN53909.1 - 7.2e-07 29.1 1.7 7.2e-07 29.1 1.7 2.2 2 1 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RLN53909.1 - 1.8e-06 27.7 1.8 5.4e-06 26.2 1.8 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 RLN53909.1 - 1.9e-06 27.8 1.0 5e-06 26.5 1.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 RLN53909.1 - 3.9e-06 26.6 2.4 3.9e-06 26.6 2.4 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN53909.1 - 1.6e-05 24.6 0.8 1.6e-05 24.6 0.8 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN53909.1 - 5.8e-05 22.9 5.3 5.8e-05 22.9 5.3 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN53909.1 - 9.9e-05 22.3 5.1 0.00017 21.6 1.2 2.8 2 1 1 3 3 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 RLN53909.1 - 0.00073 19.2 12.0 0.0014 18.4 0.7 3.7 4 0 0 4 4 4 2 RING-like zinc finger FANCL_C PF11793.8 RLN53909.1 - 0.012 15.7 3.9 0.083 13.1 3.9 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 RLN53909.1 - 0.014 15.0 1.5 0.014 15.0 1.5 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 RLN53909.1 - 0.048 13.8 2.9 0.048 13.8 2.9 2.7 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 RLN53909.1 - 1.5 9.0 4.5 2.5 8.3 0.3 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 MFS_1_like PF12832.7 RLN53910.1 - 3.9e-62 210.3 20.6 7e-62 209.5 20.6 1.4 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RLN53910.1 - 7.4e-19 67.9 35.4 1.9e-18 66.5 29.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 RLN53910.1 - 2.3e-16 59.8 17.3 3e-16 59.4 17.3 1.0 1 0 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 RLN53910.1 - 1.6e-14 53.5 15.7 4.4e-14 52.1 15.7 1.6 1 1 0 1 1 1 1 LacY proton/sugar symporter MFS_2 PF13347.6 RLN53910.1 - 3.3e-06 25.9 22.4 0.00032 19.4 9.6 2.5 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.13 RLN53910.1 - 0.05 12.0 18.9 0.15 10.4 18.9 1.6 1 1 0 1 1 1 0 Transmembrane secretion effector S-methyl_trans PF02574.16 RLN53911.1 - 2.2e-64 217.8 0.0 2.6e-64 217.6 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase RasGAP PF00616.19 RLN53920.1 - 2.4e-18 66.6 0.0 9.7e-13 48.3 0.0 3.4 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase Gemin6 PF06372.12 RLN53920.1 - 3.6e-05 23.4 0.0 6.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Gemin6 protein START PF01852.19 RLN53920.1 - 0.00015 21.3 0.0 0.00045 19.7 0.0 1.7 2 0 0 2 2 2 1 START domain SM-ATX PF14438.6 RLN53920.1 - 0.057 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Ataxin 2 SM domain Glyco_trans_2_3 PF13632.6 RLN53921.1 - 4.9e-15 56.0 0.0 4.9e-15 56.0 0.0 3.5 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.14 RLN53921.1 - 1.5e-11 43.5 5.3 2.7e-07 29.5 0.0 3.6 3 1 1 4 4 4 2 Cellulose synthase Glyco_tranf_2_3 PF13641.6 RLN53921.1 - 1.1e-09 38.6 0.0 2.9e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 RLN53921.1 - 2.8e-07 30.5 0.0 0.013 15.3 0.0 3.2 3 0 0 3 3 3 2 Glycosyl transferase family 2 PH PF00169.29 RLN53921.1 - 4e-07 30.5 0.1 1.1e-06 29.1 0.0 1.8 2 0 0 2 2 2 1 PH domain Glyco_transf_21 PF13506.6 RLN53921.1 - 4.4e-06 26.3 0.1 0.00045 19.8 0.1 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 PH_11 PF15413.6 RLN53921.1 - 0.0027 18.1 0.4 0.0085 16.5 0.4 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 RLN53921.1 - 0.25 11.6 2.0 1.1 9.6 0.2 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain zf-C6H2 PF15801.5 RLN53921.1 - 0.95 9.8 18.2 0.023 15.0 10.3 2.3 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding RabGAP-TBC PF00566.18 RLN53922.1 - 1.4e-06 28.1 0.1 2.7e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Astro_capsid_p PF12226.8 RLN53922.1 - 1.3 8.1 7.0 1.8 7.6 7.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein HTH_Tnp_Tc5 PF03221.16 RLN53933.1 - 0.00091 19.2 0.0 0.0043 17.0 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 RLN53933.1 - 0.0087 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease PIN_8 PF18476.1 RLN53933.1 - 3.3 7.5 4.8 4 7.2 1.7 2.3 2 1 1 3 3 3 0 PIN like domain Sugar_tr PF00083.24 RLN53944.1 - 1.2e-52 179.3 26.4 1.7e-52 178.8 26.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN53944.1 - 8.1e-30 103.9 50.8 2.7e-25 89.0 29.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 RLN53944.1 - 2.2e-06 27.2 7.6 2.2e-06 27.2 7.6 2.1 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB PH PF00169.29 RLN53953.1 - 1.4e-09 38.4 0.1 2.6e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN53953.1 - 0.00093 19.4 0.1 0.0015 18.7 0.1 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 RLN53953.1 - 0.014 15.8 4.6 5.2 7.5 4.6 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain DUF4551 PF15087.6 RLN53953.1 - 0.24 10.2 8.4 0.26 10.1 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF3915 PF13054.6 RLN53953.1 - 0.35 10.8 8.6 0.87 9.6 8.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) PH PF00169.29 RLN53954.1 - 9e-14 51.9 0.1 0.00065 20.2 0.0 3.5 3 1 0 3 3 3 3 PH domain PH_11 PF15413.6 RLN53954.1 - 0.027 14.9 1.2 0.47 10.9 0.0 3.3 3 3 0 3 3 3 0 Pleckstrin homology domain GRIP PF01465.20 RLN53955.1 - 1.8e-15 56.5 0.0 4.9e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 GRIP domain Bcr-Abl_Oligo PF09036.10 RLN53955.1 - 0.076 13.0 0.2 0.076 13.0 0.2 6.3 7 2 1 8 8 8 0 Bcr-Abl oncoprotein oligomerisation domain cNMP_binding PF00027.29 RLN53956.1 - 3.9e-15 55.7 0.0 1.4e-09 37.9 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN53956.1 - 1.1e-12 47.7 10.8 2.5e-12 46.6 10.8 1.5 1 0 0 1 1 1 1 Ion transport protein Kinesin PF00225.23 RLN53978.1 - 7.9e-72 242.0 11.6 4.9e-39 134.2 0.5 2.8 2 1 1 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 RLN53978.1 - 3e-25 88.9 0.0 7.7e-25 87.6 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding UvrD-helicase PF00580.21 RLN53978.1 - 1.1 8.7 8.4 14 5.1 0.3 3.1 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain GFA PF04828.14 RLN53979.1 - 5.5e-10 39.5 0.9 5.5e-10 39.5 0.9 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L37e PF01907.19 RLN53979.1 - 0.014 15.5 0.3 0.037 14.2 0.3 1.6 1 0 0 1 1 1 0 Ribosomal protein L37e Pkinase PF00069.25 RLN53981.1 - 5.1e-25 88.3 0.2 4.2e-15 55.8 0.2 2.3 1 1 1 2 2 2 2 Protein kinase domain DNase_II PF03265.15 RLN53981.1 - 6.9e-11 42.0 0.0 2.9e-08 33.4 0.0 3.4 2 1 0 2 2 2 1 Deoxyribonuclease II EF-hand_7 PF13499.6 RLN53981.1 - 1.1e-08 35.4 0.6 2.3e-07 31.2 0.5 2.7 2 0 0 2 2 2 1 EF-hand domain pair Pkinase_Tyr PF07714.17 RLN53981.1 - 1.5e-08 34.2 0.0 3e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_8 PF13833.6 RLN53981.1 - 1.9e-08 34.0 0.7 9e-08 31.8 0.5 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN53981.1 - 3.5e-08 32.4 0.3 4.9e-05 22.6 0.6 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RLN53981.1 - 1.7e-06 27.5 1.2 0.17 11.9 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain SPARC_Ca_bdg PF10591.9 RLN53981.1 - 0.17 12.2 0.2 0.57 10.5 0.1 2.0 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region AAA_6 PF12774.7 RLN53982.1 - 3.6e-120 400.9 0.0 8.1e-118 393.1 0.0 3.5 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN53982.1 - 7.6e-97 324.9 2.2 7.6e-97 324.9 2.2 4.0 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 RLN53982.1 - 1.5e-68 230.3 2.6 2.1e-68 229.8 0.0 2.8 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_8 PF12780.7 RLN53982.1 - 1.4e-49 168.8 0.0 1.8e-47 161.9 0.0 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 RLN53982.1 - 9.5e-36 123.1 0.0 2e-35 122.0 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RLN53982.1 - 1.1e-35 122.3 0.0 1e-31 109.5 0.1 3.1 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 RLN53982.1 - 3.9e-35 120.8 0.0 9.6e-23 80.7 0.0 5.2 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) Dynein_C PF18199.1 RLN53982.1 - 3.3e-32 112.0 1.7 4.2e-32 111.6 0.1 2.0 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 RLN53982.1 - 1.6e-29 102.7 4.5 1.4e-26 93.1 0.0 3.5 4 0 0 4 4 3 2 P-loop containing dynein motor region DHC_N1 PF08385.12 RLN53982.1 - 1.1e-28 100.3 4.5 2.2e-28 99.3 0.1 3.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 MT PF12777.7 RLN53982.1 - 1.3e-28 100.0 9.0 3.2e-28 98.7 9.0 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA PF00004.29 RLN53982.1 - 7.7e-07 29.6 0.1 0.39 11.2 0.0 5.7 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN53982.1 - 5.5e-05 23.5 11.3 0.67 10.2 0.0 6.0 7 0 0 7 7 4 2 AAA domain IstB_IS21 PF01695.17 RLN53982.1 - 9.4e-05 22.2 0.2 0.23 11.2 0.0 3.6 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_24 PF13479.6 RLN53982.1 - 0.0002 21.2 0.0 0.17 11.6 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.6 RLN53982.1 - 0.00037 20.7 2.7 1.8 8.7 0.0 4.9 5 0 0 5 5 4 1 AAA domain AAA_30 PF13604.6 RLN53982.1 - 0.001 18.9 0.2 0.46 10.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 RLN53982.1 - 0.001 19.0 11.2 0.031 14.2 0.0 5.4 6 0 0 6 6 5 1 RsgA GTPase AAA_29 PF13555.6 RLN53982.1 - 0.0022 17.7 0.1 0.25 11.1 0.0 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN53982.1 - 0.0026 18.2 28.8 0.066 13.6 0.0 9.1 9 2 1 10 10 6 2 AAA ATPase domain ATPase_2 PF01637.18 RLN53982.1 - 0.0026 17.7 0.2 0.099 12.5 0.0 3.1 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 RLN53982.1 - 0.0032 18.0 3.4 0.43 11.1 0.0 4.7 4 0 0 4 4 3 1 ABC transporter AAA_28 PF13521.6 RLN53982.1 - 0.0036 17.6 0.0 0.25 11.6 0.0 3.4 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 RLN53982.1 - 0.0048 17.5 0.0 0.76 10.3 0.0 3.7 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 RLN53982.1 - 0.02 15.3 0.1 3.6 8.0 0.0 3.3 3 0 0 3 3 3 0 RNA helicase Guanylate_kin PF00625.21 RLN53982.1 - 0.022 14.5 0.1 0.98 9.1 0.0 3.0 2 0 0 2 2 2 0 Guanylate kinase Hormone_2 PF00123.20 RLN53982.1 - 0.042 13.7 0.0 0.15 12.0 0.0 2.0 1 0 0 1 1 1 0 Peptide hormone ATP_bind_1 PF03029.17 RLN53982.1 - 0.051 13.3 1.9 0.63 9.8 0.0 3.5 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein Sigma54_activat PF00158.26 RLN53982.1 - 0.085 12.6 0.3 11 5.7 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain Rad17 PF03215.15 RLN53982.1 - 0.1 12.5 0.1 1.3 8.9 0.1 2.8 2 0 0 2 2 2 0 Rad17 P-loop domain CHD5 PF04420.14 RLN53982.1 - 8.2 6.3 9.9 2.1 8.2 2.1 3.7 3 1 0 3 3 3 0 CHD5-like protein Bac_luciferase PF00296.20 RLN53983.1 - 0.011 15.1 0.3 0.015 14.8 0.3 1.3 1 1 0 1 1 1 0 Luciferase-like monooxygenase TMEM51 PF15345.6 RLN53984.1 - 0.029 14.2 0.0 0.03 14.2 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DUF2371 PF10177.9 RLN53984.1 - 0.11 12.6 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) LSR PF05624.14 RLN53984.1 - 4.7 7.3 6.3 7.5 6.6 6.3 1.2 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) TMEM154 PF15102.6 RLN53984.1 - 6.6 6.6 10.4 12 5.8 2.7 2.1 1 1 1 2 2 2 0 TMEM154 protein family Pkinase PF00069.25 RLN53997.1 - 3.6e-16 59.3 0.0 8.8e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN53997.1 - 6.7e-09 35.4 0.0 1.5e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kelch_3 PF13415.6 RLN53998.1 - 2.5e-10 40.4 0.1 0.00077 19.7 0.0 3.5 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN53998.1 - 5.7e-07 29.4 0.0 2.7 8.1 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 RLN53998.1 - 2.3e-06 27.5 0.0 0.03 14.3 0.0 3.1 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.6 RLN53998.1 - 8e-06 26.0 0.0 1.1 9.6 0.0 3.4 2 1 0 2 2 2 2 Kelch motif Kelch_1 PF01344.25 RLN53998.1 - 0.12 12.0 0.0 1.8 8.3 0.0 2.6 3 0 0 3 3 3 0 Kelch motif Ras PF00071.22 RLN53999.1 - 1.2e-41 142.1 0.0 1.4e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN53999.1 - 3.3e-17 62.8 0.0 5e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN53999.1 - 8.2e-06 25.4 0.0 9.7e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MtN3_slv PF03083.16 RLN54001.1 - 3.9e-32 110.1 10.5 7.3e-20 70.8 3.6 2.4 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RLN54001.1 - 3.4e-05 23.5 9.0 0.0087 15.8 0.1 3.2 4 0 0 4 4 4 2 PQ loop repeat DUF3087 PF11286.8 RLN54001.1 - 1.4 8.4 4.1 17 4.9 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3087) MtN3_slv PF03083.16 RLN54002.1 - 1.8e-31 108.0 9.6 8.7e-19 67.4 0.6 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RLN54002.1 - 1.3e-05 24.9 6.1 0.00052 19.7 0.2 2.8 3 0 0 3 3 3 2 PQ loop repeat DUF5058 PF16481.5 RLN54002.1 - 3.9 7.1 11.6 0.05 13.3 1.6 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5058) MtN3_slv PF03083.16 RLN54003.1 - 2e-31 107.9 15.9 3.7e-20 71.7 4.7 2.4 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RLN54003.1 - 0.00016 21.4 7.0 0.00056 19.6 0.3 3.4 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 RLN54004.1 - 4e-32 110.1 15.1 2.1e-21 75.8 1.0 2.6 2 1 1 3 3 3 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RLN54004.1 - 0.00064 19.4 3.8 0.0019 18.0 0.2 3.0 3 0 0 3 3 3 1 PQ loop repeat TMEM173 PF15009.6 RLN54004.1 - 0.51 9.5 1.9 12 4.9 0.3 2.4 2 1 0 2 2 2 0 Transmembrane protein 173 MtN3_slv PF03083.16 RLN54005.1 - 2.3e-30 104.4 13.3 4e-18 65.2 2.9 2.1 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RLN54005.1 - 0.008 15.9 4.2 0.011 15.4 0.1 2.8 2 1 0 2 2 2 1 PQ loop repeat MtN3_slv PF03083.16 RLN54006.1 - 2.2e-28 98.1 7.7 4e-21 74.8 1.0 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange YtpI PF14007.6 RLN54006.1 - 0.22 11.7 3.7 0.69 10.1 0.5 2.8 1 1 0 2 2 2 0 YtpI-like protein DUF4149 PF13664.6 RLN54006.1 - 2.2 8.6 8.2 0.56 10.6 0.8 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4149) DUF4819 PF16090.5 RLN54028.1 - 0.075 13.1 0.3 0.14 12.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4819) DUF4629 PF15442.6 RLN54028.1 - 0.21 11.8 5.7 0.39 11.0 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) NAM-associated PF14303.6 RLN54028.1 - 2.5 8.8 18.5 26 5.5 17.9 2.2 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Myb_DNA-bind_4 PF13837.6 RLN54065.1 - 0.012 16.0 0.1 0.67 10.4 0.0 2.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Lectin_N PF03954.14 RLN54065.1 - 0.12 12.1 0.3 0.28 10.9 0.3 1.6 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain L27_1 PF09058.10 RLN54065.1 - 0.47 10.5 2.5 1 9.4 0.3 2.4 2 0 0 2 2 2 0 L27_1 Mago_nashi PF02792.14 RLN54086.1 - 8.4e-21 74.6 9.4 1.4e-19 70.6 9.4 2.3 1 1 0 1 1 1 1 Mago nashi protein E2F_TDP PF02319.20 RLN54087.1 - 1.3e-05 25.2 0.4 3e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain ORMDL PF04061.14 RLN54088.1 - 7.7e-31 106.7 0.0 9.5e-31 106.4 0.0 1.1 1 0 0 1 1 1 1 ORMDL family Ripply PF14998.6 RLN54088.1 - 0.081 13.6 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 Transcription Regulator Ras PF00071.22 RLN54089.1 - 2.3e-31 108.6 0.2 1.6e-19 70.0 0.1 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 RLN54089.1 - 6.1e-12 45.8 0.0 2.4e-07 31.0 0.0 2.3 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 RLN54089.1 - 0.051 13.5 0.0 12 5.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Arf PF00025.21 RLN54089.1 - 0.08 12.4 0.0 0.58 9.6 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family TniB PF05621.11 RLN54089.1 - 0.17 11.3 0.0 0.53 9.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Mago_nashi PF02792.14 RLN54090.1 - 6e-36 123.7 0.0 7.3e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Mago nashi protein Tim17 PF02466.19 RLN54100.1 - 9.3e-06 26.0 12.2 3.8e-05 24.0 12.2 1.8 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family EamA PF00892.20 RLN54100.1 - 0.0041 17.3 3.2 0.0054 16.9 3.2 1.1 1 0 0 1 1 1 1 EamA-like transporter family Bacteriocin_IIc PF10439.9 RLN54100.1 - 0.0097 16.0 11.5 0.0097 16.0 11.5 2.4 2 0 0 2 2 2 1 Bacteriocin class II with double-glycine leader peptide DUF2567 PF10821.8 RLN54100.1 - 0.055 13.5 1.8 6 6.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2567) TPD PF14811.6 RLN54100.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif Gly-zipper_Omp PF13488.6 RLN54100.1 - 5.8 7.0 31.1 3.5 7.7 21.4 2.3 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_OmpA PF13436.6 RLN54100.1 - 9.3 6.1 34.3 2.2 8.2 2.7 2.9 2 1 0 2 2 2 0 Glycine-zipper domain PKD_channel PF08016.12 RLN54101.1 - 0.00034 19.4 0.0 0.049 12.3 0.0 2.2 1 1 1 2 2 2 2 Polycystin cation channel TFIIIC_delta PF12657.7 RLN54102.1 - 4.4e-14 52.8 0.1 2.3e-12 47.2 0.0 2.3 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 RLN54102.1 - 1.4e-08 34.6 0.4 3.3e-08 33.4 0.4 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex WD40 PF00400.32 RLN54102.1 - 0.00035 21.3 9.9 0.003 18.3 0.2 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.8 RLN54102.1 - 0.025 13.3 0.1 0.041 12.5 0.1 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF5046 PF16465.5 RLN54102.1 - 0.12 11.7 0.1 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5046) DFRP_C PF16543.5 RLN54103.1 - 1 9.9 0.0 1 9.9 0.0 2.4 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 zf-RING_11 PF17123.5 RLN54117.1 - 2.6e-06 27.1 0.7 4.6e-06 26.3 0.7 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 RLN54117.1 - 0.00029 21.1 2.0 0.00048 20.4 2.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 RLN54117.1 - 0.14 12.2 0.9 0.27 11.3 0.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger PIEZO PF15917.5 RLN54117.1 - 0.16 11.4 0.8 0.25 10.8 0.8 1.3 1 0 0 1 1 1 0 Piezo CDC45 PF02724.14 RLN54128.1 - 1.5 7.0 4.2 2.5 6.3 4.2 1.2 1 0 0 1 1 1 0 CDC45-like protein CSTF_C PF14304.6 RLN54138.1 - 1.5e-11 43.7 8.6 3.4e-11 42.5 8.6 1.7 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.6 RLN54138.1 - 2e-11 44.1 0.2 2e-11 44.1 0.2 2.2 2 1 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 Coiled-coil_56 PF09813.9 RLN54138.1 - 0.079 13.0 1.3 2.5 8.2 0.1 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 56 Flu_M1_C PF08289.11 RLN54138.1 - 0.11 12.7 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Ste5 PF11610.8 RLN54138.1 - 0.2 11.6 2.3 0.35 10.8 2.3 1.4 1 0 0 1 1 1 0 Scaffold protein Ste5, Fus3-binding region Sigma70_r4_2 PF08281.12 RLN54138.1 - 0.3 10.8 2.7 2.3 8.0 0.2 2.5 1 1 1 2 2 2 0 Sigma-70, region 4 CAF1 PF04857.20 RLN54139.1 - 3.3e-85 286.1 0.5 3.3e-85 286.1 0.5 1.8 2 0 0 2 2 2 1 CAF1 family ribonuclease DHHC PF01529.20 RLN54139.1 - 7.5e-21 74.6 2.3 7.5e-21 74.6 2.3 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF2288 PF10052.9 RLN54139.1 - 0.18 11.9 0.2 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2288) IGFBP PF00219.18 RLN54139.1 - 1.7 9.3 7.2 5.3 7.8 7.2 1.8 1 0 0 1 1 1 0 Insulin-like growth factor binding protein UBA2_C PF16195.5 RLN54139.1 - 9 7.1 7.7 8.1 7.2 3.7 2.5 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus DUF382 PF04037.13 RLN54140.1 - 4.9e-57 191.6 0.2 4.9e-57 191.6 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 RLN54140.1 - 1.3e-11 44.2 7.4 3.6e-11 42.8 6.1 2.4 2 1 0 2 2 2 1 PSP PEX11 PF05648.14 RLN54141.1 - 1.2e-11 44.5 1.4 2.1e-06 27.4 0.3 2.1 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) FYVE PF01363.21 RLN54142.1 - 1.5e-07 31.4 3.1 2.9e-07 30.5 3.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger Gly_kinase PF02595.15 RLN54142.1 - 0.17 10.9 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycerate kinase family zf-B_box PF00643.24 RLN54142.1 - 0.37 11.0 9.2 0.75 10.0 9.2 1.4 1 0 0 1 1 1 0 B-box zinc finger Iso_dh PF00180.20 RLN54143.1 - 5.4e-24 85.0 0.0 7e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ank_4 PF13637.6 RLN54157.1 - 4.6e-25 87.7 10.1 0.00022 21.7 0.0 9.3 6 3 3 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN54157.1 - 8.4e-22 77.0 12.5 0.0002 21.6 0.1 10.8 5 2 7 12 12 12 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN54157.1 - 2.9e-20 72.6 0.0 0.00025 21.6 0.0 5.9 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN54157.1 - 6.5e-11 41.5 0.9 16 6.4 0.0 9.9 10 2 2 12 12 12 2 Ankyrin repeat Ank_2 PF12796.7 RLN54158.1 - 3.3e-154 501.9 18.9 4.7e-18 65.6 0.6 11.6 2 1 7 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN54158.1 - 1.1e-121 395.8 43.5 1e-10 41.9 0.1 17.1 4 3 13 18 18 18 18 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN54158.1 - 3.3e-121 380.4 12.5 4.9e-05 23.4 0.0 22.7 23 0 0 23 23 23 21 Ankyrin repeat Ank PF00023.30 RLN54158.1 - 9.3e-120 386.4 24.9 1.2e-05 25.5 0.0 22.0 22 0 0 22 22 22 21 Ankyrin repeat Ank_5 PF13857.6 RLN54158.1 - 2.1e-101 330.6 43.2 9.5e-07 29.0 0.2 19.8 1 1 17 20 20 20 20 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 RLN54158.1 - 1.8e-40 138.9 0.0 2.7e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN54158.1 - 6.6e-38 130.6 0.0 1.2e-37 129.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain YlzJ PF14035.6 RLN54158.1 - 0.0016 18.6 0.0 3e+02 1.7 0.0 7.9 11 1 0 11 11 11 0 YlzJ-like protein VWA_3_C PF18571.1 RLN54158.1 - 0.0025 17.6 7.7 1.4e+02 2.5 0.0 9.2 10 0 0 10 10 10 0 von Willebrand factor type A C-terminal domain 3HCDH_RFF PF18321.1 RLN54158.1 - 0.33 11.4 23.7 1 9.9 0.2 9.6 9 1 2 11 11 11 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain PI3_PI4_kinase PF00454.27 RLN54188.1 - 8.6e-75 251.8 0.0 1.3e-74 251.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 RLN54188.1 - 2.2e-35 121.0 1.1 5.3e-35 119.8 1.1 1.7 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 RLN54188.1 - 6.4e-17 61.1 0.3 1.6e-16 59.8 0.3 1.8 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 RLN54188.1 - 0.001 18.3 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 FAT domain NOC3p PF07540.11 RLN54189.1 - 3.7e-23 81.8 0.6 1.5e-22 79.8 0.1 2.4 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 RLN54189.1 - 2e-22 80.0 3.2 1e-21 77.7 0.2 2.6 2 0 0 2 2 2 1 CBF/Mak21 family DUF2847 PF11009.8 RLN54189.1 - 0.11 12.4 0.1 0.36 10.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) AbLIM_anchor PF16182.5 RLN54189.1 - 0.13 12.0 3.5 0.31 10.8 3.5 1.6 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM RRN3 PF05327.11 RLN54189.1 - 5.3 5.5 10.4 4.7 5.6 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 ABC_tran PF00005.27 RLN54195.1 - 1.8e-24 86.8 0.0 3.1e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN54195.1 - 3.4e-06 27.1 0.2 0.068 13.0 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 RLN54195.1 - 1.6e-05 24.4 2.1 2.2e-05 24.0 2.1 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_16 PF13191.6 RLN54195.1 - 7.3e-05 23.2 0.2 0.00016 22.1 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 RLN54195.1 - 0.00012 22.1 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN54195.1 - 0.0018 18.0 0.1 0.004 16.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN54195.1 - 0.0075 15.9 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 RLN54195.1 - 0.013 15.0 0.1 0.86 9.0 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 RLN54195.1 - 0.022 14.5 0.3 0.041 13.6 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 RLN54195.1 - 0.032 14.7 0.0 0.063 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 RLN54195.1 - 0.036 14.1 0.0 0.089 12.9 0.0 1.6 2 0 0 2 2 2 0 Dynamin family ER-remodelling PF14755.6 RLN54195.1 - 0.038 14.3 1.2 0.085 13.1 1.2 1.5 1 0 0 1 1 1 0 Intracellular membrane remodeller AAA_22 PF13401.6 RLN54195.1 - 0.045 14.0 0.2 0.22 11.8 0.1 2.4 2 1 1 3 3 3 0 AAA domain Rad17 PF03215.15 RLN54195.1 - 0.19 11.6 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Ank_4 PF13637.6 RLN54196.1 - 0.0003 21.3 0.6 0.39 11.4 0.0 3.8 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN54196.1 - 0.0049 17.4 0.0 0.29 11.8 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN54196.1 - 0.1 13.2 0.3 53 4.9 0.0 3.9 4 1 0 4 4 4 0 Ankyrin repeat Adap_comp_sub PF00928.21 RLN54207.1 - 1.9e-74 250.4 0.0 1.8e-53 181.6 0.0 2.1 1 1 1 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 RLN54207.1 - 3.6e-06 27.0 0.6 6.6e-06 26.1 0.6 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Histone PF00125.24 RLN54215.1 - 1.9 8.9 7.4 12 6.2 0.3 2.7 3 1 0 3 3 3 0 Core histone H2A/H2B/H3/H4 Kisspeptin PF15152.6 RLN54215.1 - 2.7 8.8 8.2 0.33 11.8 1.1 2.6 2 1 0 2 2 2 0 Kisspeptin Sugar_tr PF00083.24 RLN54220.1 - 2.8e-06 26.5 1.2 3.7e-06 26.1 1.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter IBN_N PF03810.19 RLN54238.1 - 3.8e-10 39.5 1.0 6e-08 32.5 0.0 4.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Pox_F11 PF04943.12 RLN54238.1 - 0.022 13.8 0.9 0.039 13.0 0.9 1.3 1 0 0 1 1 1 0 Poxvirus F11 protein Antimicrobial21 PF14861.6 RLN54238.1 - 2 8.2 5.6 4 7.2 5.6 1.5 1 0 0 1 1 1 0 Plant antimicrobial peptide PNRC PF15365.6 RLN54240.1 - 2.1e-06 27.4 3.1 2.1e-06 27.4 3.1 2.4 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif zf-RING_2 PF13639.6 RLN54241.1 - 1.3e-09 38.2 5.8 1.3e-09 38.2 5.8 4.4 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN54241.1 - 2.7e-08 33.5 4.5 2.7e-08 33.5 4.5 4.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN54241.1 - 2.6e-07 30.8 4.2 2.6e-07 30.8 4.2 3.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 RLN54241.1 - 8.8e-07 28.7 2.1 8.8e-07 28.7 2.1 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN54241.1 - 0.006 16.3 4.4 0.006 16.3 4.4 3.1 2 1 0 2 2 2 1 RING-like zinc finger TCR PF03638.15 RLN54241.1 - 0.017 15.4 15.9 0.017 15.4 15.9 3.4 3 1 0 3 3 3 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain KIAA1328 PF15369.6 RLN54241.1 - 7.3 6.3 10.6 0.35 10.7 1.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein KIAA1328 DIM1 PF02966.16 RLN54242.1 - 6.9e-66 220.0 0.1 7.8e-66 219.9 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 RLN54242.1 - 0.0039 17.2 0.0 0.0054 16.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin NDK PF00334.19 RLN54243.1 - 1.7e-35 122.0 0.0 1.1e-21 77.2 0.0 2.1 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 RLN54243.1 - 0.056 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 DUF1126 PH-like domain Aldo_ket_red PF00248.21 RLN54244.1 - 5.5e-58 196.5 0.0 6.5e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Erf4 PF10256.9 RLN54245.1 - 0.0098 16.0 0.0 0.037 14.1 0.0 1.8 2 0 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family Ephrin_rec_like PF07699.13 RLN54245.1 - 0.028 14.2 1.2 0.074 12.8 1.2 1.8 1 0 0 1 1 1 0 Putative ephrin-receptor like Arrestin_C PF02752.22 RLN54246.1 - 2.1e-12 47.6 0.0 7.1e-10 39.4 0.0 2.8 2 1 1 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 RLN54246.1 - 0.00042 20.4 0.0 0.097 12.7 0.0 2.6 1 1 1 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Pilus_CpaD PF09476.10 RLN54247.1 - 0.043 13.5 2.0 0.14 11.9 2.0 1.9 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) MORN PF02493.20 RLN54249.1 - 1.8e-40 134.5 45.0 2.6e-07 30.1 1.1 8.6 9 0 0 9 9 9 8 MORN repeat JmjC PF02373.22 RLN54249.1 - 0.11 12.9 0.6 2.1 8.8 0.0 2.7 3 0 0 3 3 3 0 JmjC domain, hydroxylase DUF3255 PF11631.8 RLN54249.1 - 0.34 10.8 2.4 4.7 7.1 0.2 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF3255) Aldo_ket_red PF00248.21 RLN54250.1 - 3.3e-67 226.8 0.0 4e-67 226.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hus1 PF04005.12 RLN54250.1 - 0.15 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Hus1-like protein PAH PF02671.21 RLN54251.1 - 1.7e-28 98.5 7.7 1.2e-14 54.1 0.2 2.6 2 0 0 2 2 2 2 Paired amphipathic helix repeat Ku_PK_bind PF08785.11 RLN54251.1 - 4.5e-05 23.6 0.8 0.3 11.2 0.0 3.2 3 0 0 3 3 3 2 Ku C terminal domain like IL5 PF02025.15 RLN54251.1 - 0.051 13.9 0.0 0.98 9.7 0.0 2.3 1 1 1 2 2 2 0 Interleukin 5 MT0933_antitox PF14013.6 RLN54251.1 - 2.3 8.6 5.5 4.8 7.6 0.9 2.9 3 0 0 3 3 3 0 MT0933-like antitoxin protein SR-25 PF10500.9 RLN54252.1 - 0.052 13.2 8.9 0.08 12.6 8.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF5066 PF16728.5 RLN54253.1 - 0.3 10.4 4.4 1.7 7.9 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5066) Tho2 PF11262.8 RLN54253.1 - 0.41 9.8 2.1 3.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 ABC_tran_CTD PF16326.5 RLN54253.1 - 1.1 9.5 5.9 0.15 12.4 0.9 2.1 3 0 0 3 3 3 0 ABC transporter C-terminal domain FUSC PF04632.12 RLN54254.1 - 3.9 5.9 8.0 5.4 5.4 8.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family bZIP_2 PF07716.15 RLN54254.1 - 6.4 7.0 9.2 0.37 10.9 3.7 1.8 2 0 0 2 2 2 0 Basic region leucine zipper Pkinase_Tyr PF07714.17 RLN54282.1 - 4.6e-58 196.5 0.0 4.7e-44 150.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN54282.1 - 2e-50 171.6 0.0 1.1e-37 129.9 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 RLN54282.1 - 0.0012 18.2 0.0 0.22 10.8 0.0 3.1 3 0 0 3 3 3 1 Kinase-like HEAT_2 PF13646.6 RLN54282.1 - 0.008 16.5 0.4 0.05 14.0 0.1 2.5 2 0 0 2 2 2 1 HEAT repeats Arm PF00514.23 RLN54282.1 - 0.058 13.5 0.0 1.4 9.0 0.0 2.9 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat APH PF01636.23 RLN54282.1 - 0.071 13.0 0.1 0.93 9.4 0.0 2.8 3 0 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN54282.1 - 0.11 11.9 0.0 2.2 7.6 0.0 2.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family WW PF00397.26 RLN54288.1 - 4.1e-20 71.6 13.3 2.6e-10 40.2 2.2 2.5 2 0 0 2 2 2 2 WW domain FF PF01846.19 RLN54288.1 - 2.1e-08 34.2 0.2 1.5e-05 25.1 0.0 2.8 2 1 0 2 2 2 2 FF domain Glyco_hyd_101C PF17451.2 RLN54288.1 - 0.016 15.4 5.7 1.1 9.5 0.4 2.8 2 1 1 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain DUF4887 PF16228.5 RLN54288.1 - 0.79 9.9 11.9 1.3 9.2 11.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) DUF733 PF05306.11 RLN54288.1 - 7.4 6.9 9.4 26 5.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF733) MPLKIP PF15502.6 RLN54289.1 - 4.4e-11 42.8 11.2 1.6e-07 31.4 1.9 2.8 1 1 0 2 2 2 2 M-phase-specific PLK1-interacting protein FoP_duplication PF13865.6 RLN54289.1 - 9.3 6.9 22.1 1.6 9.3 18.4 1.7 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 SLD5_C PF16922.5 RLN54291.1 - 2e-15 56.7 0.0 4.2e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 RLN54291.1 - 0.0022 18.5 0.3 0.0082 16.6 0.2 1.9 1 1 1 2 2 2 1 GINS complex protein MIS13 PF08202.11 RLN54291.1 - 0.037 13.3 0.0 0.046 13.0 0.0 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family SART-1 PF03343.13 RLN54293.1 - 2.3e-83 280.9 96.1 1e-66 225.9 69.6 3.9 2 1 1 3 3 3 2 SART-1 family BBS2_C PF14782.6 RLN54294.1 - 0.019 13.8 0.8 0.023 13.5 0.8 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Dynein_C PF18199.1 RLN54294.1 - 0.023 14.0 0.2 0.026 13.7 0.2 1.1 1 0 0 1 1 1 0 Dynein heavy chain C-terminal domain DASH_Dam1 PF08653.10 RLN54294.1 - 0.053 13.3 2.7 6.5 6.6 0.3 2.5 1 1 1 2 2 2 0 DASH complex subunit Dam1 Baculo_PEP_C PF04513.12 RLN54294.1 - 0.12 12.4 4.0 0.18 11.9 4.0 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Abhydrolase_9_N PF15420.6 RLN54295.1 - 0.12 12.4 5.2 0.24 11.4 4.4 2.0 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus Neurensin PF14927.6 RLN54295.1 - 0.15 11.8 2.1 0.27 10.9 0.6 2.2 1 1 1 2 2 2 0 Neurensin TNFR_16_TM PF18422.1 RLN54295.1 - 0.29 11.1 1.5 1.3 9.0 1.5 2.1 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Sugar_tr PF00083.24 RLN54298.1 - 0.00045 19.2 3.0 0.00051 19.0 3.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter PLDc_2 PF13091.6 RLN54313.1 - 5.6e-07 29.5 0.0 1.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.22 RLN54313.1 - 2.1e-05 24.5 0.0 4.9e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Phospholipase D Active site motif PIF1 PF05970.14 RLN54320.1 - 4.9e-20 72.0 0.1 7.9e-20 71.3 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 RLN54320.1 - 6.7e-11 42.3 0.1 1.2e-10 41.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RLN54320.1 - 1.4e-06 28.7 0.0 2.9e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RLN54320.1 - 0.056 13.8 0.2 0.27 11.6 0.1 2.1 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 RLN54320.1 - 0.071 13.4 0.3 0.37 11.1 0.2 2.2 1 1 0 1 1 1 0 AAA domain Cupin_1 PF00190.22 RLN54321.1 - 0.11 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Cupin CDC14 PF08045.11 RLN54321.1 - 0.11 11.6 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Cell division control protein 14, SIN component DUF4246 PF14033.6 RLN54326.1 - 3.7e-33 115.3 0.0 5.5e-32 111.5 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) ZZ PF00569.17 RLN54327.1 - 3.5e-07 29.9 0.8 6.5e-07 29.1 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type DnaJ_CXXCXGXG PF00684.19 RLN54327.1 - 0.016 15.6 4.2 0.16 12.4 3.6 2.2 1 1 1 2 2 2 0 DnaJ central domain zf-SNAP50_C PF12251.8 RLN54327.1 - 0.18 11.5 0.1 0.26 11.0 0.1 1.2 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal Asp PF00026.23 RLN54328.1 - 4.1e-36 125.0 0.0 5.5e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RLN54328.1 - 1.1e-12 48.5 0.2 1.8e-07 31.6 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 RLN54328.1 - 5.7e-09 35.9 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 RLN54328.1 - 0.016 15.8 0.5 2.1 9.1 0.2 2.6 2 1 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 RLN54328.1 - 0.052 14.1 0.0 7 7.3 0.0 2.7 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Tcp11 PF05794.13 RLN54333.1 - 2.5e-61 208.2 0.1 2.5e-61 208.2 0.1 2.0 2 0 0 2 2 2 1 T-complex protein 11 Holin_BhlA PF10960.8 RLN54333.1 - 0.098 12.6 0.1 0.098 12.6 0.1 1.9 2 0 0 2 2 2 0 BhlA holin family DNA_topoisoIV PF00521.20 RLN54333.1 - 0.23 10.3 1.4 0.37 9.6 1.4 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Rcd1 PF04078.13 RLN54334.1 - 1.5e-121 404.6 0.0 5.2e-121 402.9 0.0 1.7 1 1 0 1 1 1 1 Cell differentiation family, Rcd1-like EF-hand_7 PF13499.6 RLN54336.1 - 0.0058 17.0 0.2 0.044 14.3 0.1 2.2 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN54336.1 - 0.21 11.2 0.6 2.2 8.0 0.0 2.7 3 0 0 3 3 3 0 EF hand TMEM51 PF15345.6 RLN54358.1 - 0.0012 18.8 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 Rax2 PF12768.7 RLN54358.1 - 0.061 12.8 0.1 0.83 9.1 0.0 2.4 2 0 0 2 2 2 0 Cortical protein marker for cell polarity CcmD PF04995.14 RLN54358.1 - 1.9 8.6 5.1 0.92 9.6 1.3 2.2 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Beach PF02138.18 RLN54359.1 - 7.9e-114 379.7 0.0 1.7e-113 378.6 0.0 1.6 2 0 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 RLN54359.1 - 2.4e-14 53.3 0.2 1.3e-13 50.8 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 RLN54359.1 - 2.9e-14 53.0 0.1 6.1e-14 51.9 0.1 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 RLN54359.1 - 1e-05 25.8 0.0 2.1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 RLN54359.1 - 0.0021 18.8 0.9 0.17 12.8 0.1 3.2 2 0 0 2 2 2 1 WD domain, G-beta repeat GST_C_3 PF14497.6 RLN54360.1 - 4.7e-22 78.1 0.0 2e-21 76.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RLN54360.1 - 7.1e-08 32.6 0.0 3.2e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RLN54360.1 - 2.4e-05 24.6 0.0 6.3e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN54360.1 - 0.0022 18.0 0.3 0.015 15.3 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RLN54360.1 - 0.0025 18.1 0.0 0.0059 16.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 RLN54360.1 - 0.0043 17.4 0.0 0.008 16.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MIOX PF05153.15 RLN54364.1 - 3.3e-06 26.9 0.2 4e-06 26.6 0.2 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase MIOX PF05153.15 RLN54365.1 - 4.6e-11 42.8 0.0 5.5e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase Mog1 PF04603.12 RLN54374.1 - 2.9e-40 137.8 0.0 3.7e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein TIP49 PF06068.13 RLN54375.1 - 1.1e-156 521.5 0.3 1.4e-156 521.2 0.3 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 RLN54375.1 - 1.6e-22 79.4 0.3 4.4e-22 78.0 0.3 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 RLN54375.1 - 6.9e-09 36.2 1.3 1.7e-05 25.2 0.0 3.4 3 1 1 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN54375.1 - 4.4e-06 27.0 0.3 0.01 16.1 0.0 2.7 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.12 RLN54375.1 - 5.2e-06 26.3 0.4 0.009 15.8 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RLN54375.1 - 0.00092 19.2 0.3 0.11 12.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RLN54375.1 - 0.002 18.5 0.3 0.045 14.1 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 RLN54375.1 - 0.0057 17.0 3.6 0.19 12.0 3.6 2.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 RLN54375.1 - 0.011 15.3 0.1 0.028 14.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 RLN54375.1 - 0.011 15.1 0.2 0.41 10.0 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 RLN54375.1 - 0.014 15.1 0.1 6.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 RLN54375.1 - 0.015 15.5 0.1 0.076 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 RLN54375.1 - 0.02 14.2 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ResIII PF04851.15 RLN54375.1 - 0.05 13.6 0.1 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ATPase PF06745.13 RLN54375.1 - 0.054 12.8 0.9 0.47 9.8 0.1 2.3 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 RLN54375.1 - 0.12 13.0 0.0 0.31 11.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 RLN54375.1 - 0.12 11.7 0.3 0.28 10.4 0.3 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 RLN54375.1 - 0.13 11.7 0.1 0.52 9.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 RLN54375.1 - 0.14 11.9 0.7 5.2 6.7 0.2 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RLN54375.1 - 0.17 11.8 0.1 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Cu-oxidase_2 PF07731.14 RLN54393.1 - 4.5e-22 78.3 1.2 4.5e-22 78.3 1.2 2.6 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN54393.1 - 5.2e-13 49.1 0.2 7.6e-10 38.8 0.6 3.4 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 RLN54393.1 - 0.0012 19.0 0.0 0.0026 17.9 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase ADH_zinc_N PF00107.26 RLN54395.1 - 5.2e-25 87.9 0.5 8.3e-25 87.3 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN54395.1 - 5.9e-25 87.3 2.4 5.9e-25 87.3 2.4 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 RLN54395.1 - 3.2e-07 31.5 0.1 5.3e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 RLN54395.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase PRP4 PF08799.11 RLN54396.1 - 0.002 17.6 0.0 0.0047 16.4 0.0 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like PX PF00787.24 RLN54396.1 - 0.045 13.7 0.1 0.19 11.7 0.1 2.1 1 1 0 1 1 1 0 PX domain RNaseH_like PF04308.12 RLN54396.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease H-like MutS_V PF00488.21 RLN54397.1 - 5.2e-35 121.2 0.2 1.3e-34 119.9 0.2 1.7 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 RLN54397.1 - 1.6e-16 60.6 0.0 4.6e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 RLN54397.1 - 7.5e-06 26.3 0.4 1.6e-05 25.3 0.4 1.6 1 0 0 1 1 1 1 MutS domain III PX PF00787.24 RLN54398.1 - 6.8e-06 26.1 1.4 0.052 13.5 0.1 3.3 2 2 0 2 2 2 2 PX domain MIS13 PF08202.11 RLN54398.1 - 0.0088 15.4 1.1 1.7 7.9 0.3 2.4 2 0 0 2 2 2 2 Mis12-Mtw1 protein family Eapp_C PF10238.9 RLN54398.1 - 0.012 15.6 0.0 0.89 9.6 0.0 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF547 PF04784.14 RLN54398.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF547 PX PF00787.24 RLN54399.1 - 0.005 16.8 0.1 0.016 15.2 0.1 2.0 1 1 0 1 1 1 1 PX domain Nudix_N_2 PF14803.6 RLN54399.1 - 0.14 12.1 0.4 0.14 12.1 0.4 2.0 2 0 0 2 2 2 0 Nudix N-terminal NTP_transf_5 PF14907.6 RLN54399.1 - 0.14 11.8 0.4 1.8 8.1 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised nucleotidyltransferase Pkinase PF00069.25 RLN54406.1 - 4.1e-74 249.3 0.0 7.2e-74 248.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN54406.1 - 6.9e-35 120.6 0.0 1.2e-34 119.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 RLN54406.1 - 2.8e-07 31.0 0.0 7.7e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 PH domain IQ PF00612.27 RLN54406.1 - 3.3e-05 23.3 16.6 0.0063 16.2 2.9 4.4 3 0 0 3 3 3 2 IQ calmodulin-binding motif EF-hand_6 PF13405.6 RLN54406.1 - 5.7e-05 22.7 2.2 0.013 15.4 0.0 4.1 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 RLN54406.1 - 9.6e-05 21.7 0.6 0.001 18.4 0.0 2.9 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 RLN54406.1 - 0.0022 18.4 1.0 0.019 15.4 0.1 2.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN54406.1 - 0.02 14.4 0.1 0.34 10.5 0.0 2.6 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 RLN54406.1 - 0.025 14.4 0.0 0.4 10.6 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair FTA2 PF13095.6 RLN54406.1 - 0.091 12.4 1.2 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Sulfatase PF00884.23 RLN54407.1 - 6.2e-30 104.6 0.2 1.5e-29 103.4 0.2 1.7 1 1 0 1 1 1 1 Sulfatase DUF229 PF02995.17 RLN54407.1 - 1.1e-06 27.6 0.0 1.1e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 RLN54407.1 - 0.00091 18.9 0.0 0.0026 17.4 0.0 1.8 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Voltage_CLC PF00654.20 RLN54407.1 - 0.0095 15.2 0.1 0.031 13.5 0.0 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel WW PF00397.26 RLN54408.1 - 1.5e-05 24.9 7.6 5.8e-05 23.1 0.1 3.8 4 0 0 4 4 4 1 WW domain IQ PF00612.27 RLN54408.1 - 2.3e-05 23.8 25.9 0.012 15.4 1.0 5.2 6 0 0 6 6 6 3 IQ calmodulin-binding motif CEBP_ZZ PF16366.5 RLN54408.1 - 0.0086 16.3 40.6 0.15 12.3 0.9 6.2 6 0 0 6 6 6 4 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-B_box PF00643.24 RLN54408.1 - 0.011 15.8 6.4 0.011 15.8 6.4 5.6 5 0 0 5 5 5 0 B-box zinc finger NeA_P2 PF12312.8 RLN54408.1 - 0.073 12.5 0.9 0.16 11.4 0.9 1.5 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein GCS PF03074.16 RLN54409.1 - 4.7e-156 519.7 0.0 6.3e-156 519.3 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase PV-1 PF06637.11 RLN54409.1 - 0.065 12.0 2.3 0.11 11.3 2.3 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) PBP1_TM PF14812.6 RLN54409.1 - 0.91 9.9 4.7 3 8.3 4.7 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cactin_mid PF10312.9 RLN54410.1 - 3.7e-58 196.5 6.1 3.7e-58 196.5 6.1 1.6 2 0 0 2 2 2 1 Conserved mid region of cactin POTRA_TamA_1 PF17243.2 RLN54410.1 - 2.9 8.1 12.3 0.84 9.8 0.1 4.3 3 1 1 4 4 4 0 POTRA domain TamA domain 1 SNase PF00565.17 RLN54412.1 - 1.5e-22 80.1 0.0 2.1e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue TolA_bind_tri PF16331.5 RLN54413.1 - 0.0058 16.7 12.9 0.0058 16.7 12.9 4.3 4 0 0 4 4 4 3 TolA binding protein trimerisation ApoO PF09769.9 RLN54413.1 - 3.2 7.7 6.1 3.1 7.8 1.1 2.8 1 1 1 2 2 2 0 Apolipoprotein O Methyltransf_16 PF10294.9 RLN54414.1 - 8.9e-24 84.2 0.0 1.2e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 RLN54414.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Herpes_UL46 PF03387.14 RLN54414.1 - 0.17 10.5 0.0 0.71 8.5 0.0 1.9 2 1 0 2 2 2 0 Herpesvirus UL46 protein Glyco_hydro_30 PF02055.16 RLN54415.1 - 5e-79 265.8 0.9 6.6e-79 265.4 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Ricin_B_lectin PF00652.22 RLN54415.1 - 5e-12 46.2 3.4 1.4e-10 41.5 1.2 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Glyco_hydro_30C PF17189.4 RLN54415.1 - 9.3e-08 32.2 0.1 2.1e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 RLN54415.1 - 1.7e-07 30.7 0.0 3.2e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 RicinB_lectin_2 PF14200.6 RLN54415.1 - 1e-05 26.1 0.3 0.00055 20.6 0.2 2.5 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Glyco_hydr_30_2 PF14587.6 RLN54415.1 - 0.014 15.0 0.1 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 Pkinase PF00069.25 RLN54431.1 - 3.2e-62 210.3 0.0 4.3e-62 209.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN54431.1 - 5.9e-44 150.3 0.0 8.1e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 RLN54431.1 - 3.8e-13 49.4 0.0 2e-12 47.1 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_fungal PF17667.1 RLN54431.1 - 0.0023 16.8 0.1 0.0064 15.3 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Spt5_N PF11942.8 RLN54431.1 - 3.4 8.7 7.8 26 5.9 0.6 2.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Peptidase_C78 PF07910.13 RLN54432.1 - 0.18 11.2 0.0 9.5 5.6 0.0 2.1 2 0 0 2 2 2 0 Peptidase family C78 Transferase PF02458.15 RLN54440.1 - 7.1e-23 80.9 0.0 1.3e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Transferase family DUF1451 PF07295.11 RLN54440.1 - 1.9 8.5 7.8 5 7.1 3.6 2.3 2 0 0 2 2 2 0 Zinc-ribbon containing domain YjgF_endoribonc PF14588.6 RLN54441.1 - 1.2e-07 32.0 0.1 0.00093 19.4 0.0 2.0 2 0 0 2 2 2 2 YjgF/chorismate_mutase-like, putative endoribonuclease Mito_carr PF00153.27 RLN54451.1 - 1.4e-26 92.2 6.0 1.8e-10 40.6 0.2 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein Aminotran_3 PF00202.21 RLN54452.1 - 1.2e-110 369.9 0.0 1.4e-110 369.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Kinesin PF00225.23 RLN54453.1 - 4.8e-29 101.3 0.0 1.7e-24 86.4 0.0 2.9 2 1 0 2 2 2 2 Kinesin motor domain Exo_endo_phos PF03372.23 RLN54453.1 - 6.6e-06 25.8 0.0 1.7e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family C2 PF00168.30 RLN54453.1 - 0.00063 20.0 0.0 0.89 9.9 0.0 3.4 2 1 0 2 2 2 2 C2 domain Microtub_bd PF16796.5 RLN54453.1 - 0.0058 16.6 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Bep_C_terminal PF17841.1 RLN54453.1 - 0.2 11.9 6.2 1.8 8.8 0.5 2.9 2 0 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) DUF3987 PF13148.6 RLN54453.1 - 1.7 7.6 11.6 3.8 6.4 11.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Metal_resist PF13801.6 RLN54453.1 - 7.3 6.8 12.8 11 6.2 10.6 2.3 2 0 0 2 2 2 0 Heavy-metal resistance OrfB_Zn_ribbon PF07282.11 RLN54460.1 - 5.6e-06 26.2 2.3 5.6e-06 26.2 2.3 2.2 2 1 0 2 2 2 1 Putative transposase DNA-binding domain TMP-TENI PF02581.17 RLN54460.1 - 0.15 11.4 0.1 0.34 10.2 0.1 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase IlvN PF07991.12 RLN54461.1 - 1.2e-05 24.9 0.1 2e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Ribosomal_L7Ae PF01248.26 RLN54462.1 - 2e-22 78.7 0.2 4.8e-22 77.5 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 RLN54462.1 - 0.0043 17.1 0.2 0.035 14.2 0.2 2.1 1 1 0 1 1 1 1 RNase P subunit Pop3 DDE_Tnp_1_7 PF13843.6 RLN54471.1 - 1.4e-06 27.9 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 Ammonium_transp PF00909.21 RLN54472.1 - 2.9e-64 217.2 22.1 4e-64 216.8 22.1 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family LRR_4 PF12799.7 RLN54497.1 - 4.6e-12 46.0 0.0 0.21 12.1 0.0 7.6 7 2 1 8 8 8 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RLN54497.1 - 1.7e-09 36.9 17.2 1.6 8.9 0.0 10.9 12 0 0 12 12 12 5 Leucine Rich repeat IQ PF00612.27 RLN54497.1 - 6.9e-08 31.6 69.7 0.009 15.7 0.8 12.5 11 0 0 11 11 11 7 IQ calmodulin-binding motif LRR_1 PF00560.33 RLN54497.1 - 5.9e-07 29.2 9.0 28 5.8 0.0 9.2 8 1 1 9 9 9 1 Leucine Rich Repeat LRR_8 PF13855.6 RLN54497.1 - 0.21 11.4 2.1 5.6 6.8 0.0 4.5 6 1 0 6 6 6 0 Leucine rich repeat LRR_2 PF07723.13 RLN54497.1 - 1.2 9.9 3.9 27 5.7 0.1 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat EF-hand_7 PF13499.6 RLN54499.1 - 9.9e-38 128.4 22.7 1.5e-09 38.1 0.3 10.4 11 0 0 11 11 11 4 EF-hand domain pair EF-hand_1 PF00036.32 RLN54499.1 - 5.6e-29 97.5 25.4 0.00054 19.3 0.0 12.3 13 1 0 13 13 13 7 EF hand EF-hand_6 PF13405.6 RLN54499.1 - 1e-24 84.3 23.0 0.022 14.7 0.2 12.1 12 0 0 12 12 11 8 EF-hand domain EF-hand_8 PF13833.6 RLN54499.1 - 9.2e-22 76.7 20.6 2.9e-07 30.2 0.0 8.8 8 2 2 10 10 10 5 EF-hand domain pair EF-hand_5 PF13202.6 RLN54499.1 - 2.1e-14 52.3 20.2 0.0014 18.1 0.1 9.2 10 0 0 10 10 10 5 EF hand EF-hand_9 PF14658.6 RLN54499.1 - 1.6e-12 47.5 3.5 0.00042 20.6 0.0 7.0 8 0 0 8 8 7 2 EF-hand domain EF-hand_11 PF08976.11 RLN54499.1 - 7.6e-09 36.4 2.9 0.029 15.2 0.0 7.0 6 1 1 7 7 7 1 EF-hand domain Dockerin_1 PF00404.18 RLN54499.1 - 0.00089 19.4 0.6 0.059 13.6 0.0 3.4 3 0 0 3 3 3 1 Dockerin type I domain EF-hand_4 PF12763.7 RLN54499.1 - 0.002 18.0 2.8 0.25 11.3 0.0 5.4 8 0 0 8 8 8 1 Cytoskeletal-regulatory complex EF hand LRR_6 PF13516.6 RLN54499.1 - 0.21 11.7 3.6 0.4 10.8 0.2 2.9 3 0 0 3 3 3 0 Leucine Rich repeat TerB PF05099.13 RLN54499.1 - 1.2 9.0 7.6 14 5.6 0.0 5.3 8 0 0 8 8 8 0 Tellurite resistance protein TerB Pex19 PF04614.12 RLN54499.1 - 3 7.6 5.0 11 5.6 5.0 1.9 1 1 0 1 1 1 0 Pex19 protein family SRP_TPR_like PF17004.5 RLN54500.1 - 2.9e-11 43.4 0.4 8.4e-11 41.9 0.4 1.8 1 0 0 1 1 1 1 Putative TPR-like repeat ANAPC3 PF12895.7 RLN54500.1 - 0.00056 20.1 9.2 0.067 13.4 0.2 4.5 2 2 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 RLN54500.1 - 0.001 19.5 23.8 0.87 10.1 0.0 7.7 6 2 2 9 9 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN54500.1 - 0.0014 18.6 25.2 0.52 10.6 0.5 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN54500.1 - 0.002 18.4 1.4 0.0084 16.4 0.4 6.3 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN54500.1 - 0.0024 18.6 24.7 0.3 12.0 0.3 8.2 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN54500.1 - 0.006 16.4 14.3 3.1 7.8 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat SRP72 PF08492.12 RLN54500.1 - 0.0086 16.5 9.6 0.0086 16.5 9.6 3.0 2 1 0 2 2 2 1 SRP72 RNA-binding domain TPR_7 PF13176.6 RLN54500.1 - 0.0095 15.9 0.2 0.0095 15.9 0.2 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN54500.1 - 0.016 15.8 16.1 4.1 8.3 0.2 7.3 6 1 1 7 7 6 0 Tetratricopeptide repeat DMAP1 PF05499.12 RLN54500.1 - 0.022 14.7 0.0 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) TPR_10 PF13374.6 RLN54500.1 - 0.15 12.0 9.4 2.2 8.3 0.2 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 RLN54500.1 - 0.15 12.3 15.7 0.64 10.4 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 RLN54500.1 - 0.63 9.8 3.8 7 6.4 0.0 3.8 4 0 0 4 4 3 0 TPR repeat Ribosomal_L19 PF01245.20 RLN54501.1 - 1.2e-23 83.2 0.7 1.5e-23 82.8 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 GCP_N_terminal PF17681.1 RLN54510.1 - 2.2e-48 165.5 0.9 5.8e-47 160.8 0.0 2.3 2 0 0 2 2 2 2 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 RLN54510.1 - 7.8e-35 120.8 7.9 6e-32 111.3 4.3 2.3 2 0 0 2 2 2 2 Gamma tubulin complex component C-terminal Proteasome PF00227.26 RLN54511.1 - 9e-64 214.5 0.3 1.1e-63 214.1 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Ank_2 PF12796.7 RLN54512.1 - 3.7e-14 53.1 0.2 3.4e-05 24.3 0.4 4.8 4 2 0 4 4 4 2 Ankyrin repeats (3 copies) Ion_trans PF00520.31 RLN54512.1 - 6.4e-13 48.5 22.0 1.2e-12 47.7 22.0 1.4 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 RLN54512.1 - 4.6e-11 42.1 21.3 3e-06 26.2 14.5 2.2 1 1 1 2 2 2 2 Polycystin cation channel Ank_3 PF13606.6 RLN54512.1 - 2.9e-10 39.5 0.2 0.0017 18.7 0.1 4.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RLN54512.1 - 9.6e-10 38.5 0.0 0.0078 16.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN54512.1 - 1.9e-08 34.3 1.0 0.011 16.2 0.3 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 RLN54512.1 - 0.00021 21.8 0.0 0.059 14.0 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF1690 PF07956.11 RLN54512.1 - 0.15 12.4 1.2 0.41 11.1 1.2 1.6 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) RyR PF02026.16 RLN54513.1 - 3.3e-56 187.5 0.2 1.3e-27 95.8 0.0 3.3 3 0 0 3 3 3 2 RyR domain PKD_channel PF08016.12 RLN54513.1 - 7.3e-48 163.3 10.4 1.2e-47 162.5 10.4 1.4 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 RLN54513.1 - 4.6e-17 62.1 17.4 9e-17 61.1 17.4 1.4 1 0 0 1 1 1 1 Ion transport protein MKT1_C PF12246.8 RLN54513.1 - 0.047 12.9 0.2 0.092 12.0 0.2 1.4 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication Ac76 PF05814.11 RLN54513.1 - 8.5 6.5 12.9 3.6 7.7 0.2 3.7 4 0 0 4 4 4 0 Orf76 (Ac76) EF-hand_1 PF00036.32 RLN54514.1 - 7.4e-16 56.5 5.0 6.9e-06 25.3 0.1 5.2 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 RLN54514.1 - 8e-14 50.3 5.5 4e-05 23.2 0.2 5.2 5 0 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.6 RLN54514.1 - 8.5e-13 48.6 2.0 2e-05 25.0 0.2 4.0 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN54514.1 - 3.6e-11 42.0 8.7 5.3e-06 25.7 0.1 5.0 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 RLN54514.1 - 9.9e-09 34.9 1.6 0.00033 20.4 0.0 4.7 5 0 0 5 5 5 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RLN54514.1 - 7.7e-06 26.2 0.0 0.037 14.4 0.0 3.1 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Amidohydro_1 PF01979.20 RLN54515.1 - 7.3e-71 239.3 2.5 1.1e-70 238.7 2.5 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 RLN54515.1 - 5.6e-53 178.4 4.1 5.6e-53 178.4 4.1 1.9 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 RLN54515.1 - 1.3e-38 131.0 0.2 3.2e-38 129.7 0.0 1.8 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 RLN54515.1 - 1.9e-27 95.5 5.5 3.3e-14 53.0 0.2 3.2 2 1 1 3 3 3 2 Urease, gamma subunit Amidohydro_3 PF07969.11 RLN54515.1 - 4.1e-06 26.5 0.3 0.0028 17.2 0.0 2.7 2 0 0 2 2 2 2 Amidohydrolase family DUF2009 PF09418.10 RLN54516.1 - 8.9e-201 667.8 0.0 1.1e-200 667.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 RLN54516.1 - 7.1e-05 22.9 14.0 0.00012 22.1 12.7 2.0 2 0 0 2 2 2 1 B-box zinc finger CEBP_ZZ PF16366.5 RLN54516.1 - 0.01 16.0 11.4 0.021 15.0 11.4 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain WD40 PF00400.32 RLN54517.1 - 4.5e-28 96.9 4.2 3.5e-06 27.7 0.1 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 RLN54517.1 - 2.1e-14 53.2 0.7 0.0041 16.1 0.1 4.1 1 1 2 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 RLN54517.1 - 9.8e-14 51.4 0.1 0.0045 17.2 0.0 4.7 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 RLN54517.1 - 2e-12 46.6 0.0 3.6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Nup160 PF11715.8 RLN54517.1 - 0.00027 19.7 0.0 0.22 10.1 0.1 2.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Hira PF07569.11 RLN54517.1 - 0.082 12.6 0.2 4.4 7.0 0.0 3.2 3 1 0 3 3 3 0 TUP1-like enhancer of split WD40_like PF17005.5 RLN54517.1 - 0.13 11.6 0.0 16 4.7 0.0 2.5 2 0 0 2 2 2 0 WD40-like domain Pkinase PF00069.25 RLN54518.1 - 2.7e-48 164.6 0.0 3.9e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN54518.1 - 8.1e-47 159.7 0.0 1.2e-46 159.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Arm_APC_u3 PF16629.5 RLN54518.1 - 0.056 13.0 0.0 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Armadillo-associated region on APC Pkinase PF00069.25 RLN54519.1 - 6.2e-49 166.7 0.0 8.9e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN54519.1 - 4.4e-44 150.7 0.0 5.9e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 RLN54519.1 - 8.7e-05 22.2 0.9 0.012 15.4 0.2 2.6 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 RLN54519.1 - 0.0037 17.6 2.6 0.7 10.4 0.3 2.9 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) AbiEi_3_N PF17194.4 RLN54519.1 - 0.12 12.4 0.1 1 9.5 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain LRR_1 PF00560.33 RLN54519.1 - 0.12 13.0 0.0 7.2 7.6 0.1 3.2 2 0 0 2 2 2 0 Leucine Rich Repeat Pkinase_fungal PF17667.1 RLN54519.1 - 0.14 10.9 0.1 0.2 10.4 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 RLN54519.1 - 0.14 12.0 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN54519.1 - 0.22 10.8 0.5 0.36 10.2 0.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 RLN54521.1 - 7.8e-49 166.4 0.0 1.3e-48 165.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN54521.1 - 2.4e-47 161.4 0.0 3.5e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 RLN54521.1 - 1.8e-10 40.4 5.8 1.6e-05 24.6 0.2 2.9 2 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 RLN54521.1 - 1.3e-06 28.6 8.0 0.00095 19.5 0.7 4.0 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN54521.1 - 0.0012 19.1 0.0 14 6.7 0.0 4.1 3 0 0 3 3 3 1 Leucine Rich Repeat Pkinase_fungal PF17667.1 RLN54521.1 - 0.0032 16.3 0.1 0.0083 14.9 0.1 1.7 1 0 0 1 1 1 1 Fungal protein kinase LRR_6 PF13516.6 RLN54521.1 - 0.0061 16.5 8.7 2.3 8.5 0.2 4.6 5 0 0 5 5 5 2 Leucine Rich repeat APH PF01636.23 RLN54521.1 - 0.025 14.5 0.4 0.15 12.0 0.4 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4381 PF14316.6 RLN54521.1 - 0.025 14.8 0.1 0.072 13.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Kdo PF06293.14 RLN54521.1 - 0.17 11.2 0.1 0.31 10.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4131 PF13567.6 RLN54521.1 - 0.28 10.8 1.0 2.2 7.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Pkinase PF00069.25 RLN54522.1 - 7e-48 163.3 0.0 1.1e-47 162.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN54522.1 - 6.2e-42 143.7 0.0 9.1e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 RLN54522.1 - 0.00075 19.2 2.1 0.0026 17.5 2.1 2.0 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 RLN54522.1 - 0.014 15.8 3.9 0.37 11.3 1.7 2.8 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) Haspin_kinase PF12330.8 RLN54522.1 - 0.094 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FHA PF00498.26 RLN54523.1 - 4.3e-08 33.4 0.0 7.2e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 RLN54523.1 - 0.18 12.1 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 FHA domain Synaptobrevin PF00957.21 RLN54529.1 - 3e-30 103.9 0.1 4e-30 103.5 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 RLN54529.1 - 3.6e-24 84.6 0.1 6.3e-24 83.8 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Potass_KdpF PF09604.10 RLN54529.1 - 0.53 10.3 8.3 1.1 9.4 8.3 1.5 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) B56 PF01603.20 RLN54530.1 - 1.2e-13 50.8 0.0 1.9e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Motile_Sperm PF00635.26 RLN54531.1 - 2.2e-08 33.9 0.0 3.3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Mito_fiss_reg PF05308.11 RLN54531.1 - 0.039 14.0 1.8 0.065 13.3 1.8 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 RLN54531.1 - 1.9 7.9 5.5 2.6 7.4 5.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FYVE PF01363.21 RLN54532.1 - 3.2 8.0 9.3 7.9 6.7 9.3 1.6 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN54532.1 - 4.5 7.5 6.7 10 6.4 6.7 1.5 1 1 0 1 1 1 0 FYVE-type zinc finger BUD22 PF09073.10 RLN54532.1 - 5.4 6.2 8.8 8.1 5.7 8.8 1.3 1 0 0 1 1 1 0 BUD22 DUF1211 PF06736.11 RLN54541.1 - 0.12 12.8 0.1 0.28 11.7 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1211) Med26 PF08711.11 RLN54542.1 - 1.8e-15 56.7 0.3 1.2e-14 54.0 0.1 2.3 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Rootletin PF15035.6 RLN54543.1 - 0.0063 16.6 1.6 0.0063 16.6 1.6 5.4 2 1 2 4 4 4 1 Ciliary rootlet component, centrosome cohesion DUF1181 PF06680.11 RLN54544.1 - 0.022 14.6 0.1 0.06 13.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1181) Dicty_CAR PF05462.11 RLN54544.1 - 0.1 11.7 7.7 0.16 11.1 7.7 1.2 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor VPS13 PF16908.5 RLN54564.1 - 2.1e-47 161.9 0.0 1.6e-45 155.8 0.0 3.8 4 1 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 RLN54564.1 - 3.9e-25 88.2 0.3 1.7e-24 86.1 0.0 2.4 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 RLN54564.1 - 6e-12 45.5 0.1 7.5e-05 22.3 0.1 6.2 4 1 0 4 4 4 4 Repeating coiled region of VPS13 SPOR PF05036.13 RLN54564.1 - 0.36 11.3 1.8 1.7 9.1 1.8 2.2 1 0 0 1 1 1 0 Sporulation related domain peroxidase PF00141.23 RLN54570.1 - 5.5e-07 29.5 0.0 9.1e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Peroxidase RskA PF10099.9 RLN54570.1 - 0.0054 17.0 0.8 0.0057 17.0 0.8 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA AIRC PF00731.20 RLN54570.1 - 0.014 15.0 1.5 0.02 14.5 1.5 1.3 1 0 0 1 1 1 0 AIR carboxylase bacHORMA_1 PF18138.1 RLN54570.1 - 0.076 12.9 0.1 0.095 12.6 0.1 1.1 1 0 0 1 1 1 0 Bacterial HORMA domain family 1 MYEOV2 PF15004.6 RLN54570.1 - 0.094 13.2 0.5 1.3 9.5 0.2 2.1 2 0 0 2 2 2 0 Myeloma-overexpressed-like Herpes_TAF50 PF03326.13 RLN54570.1 - 0.11 11.1 0.0 0.12 11.0 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) PDEase_I PF00233.19 RLN54571.1 - 2.3e-67 227.2 6.0 2.3e-67 227.2 6.0 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 RLN54571.1 - 4e-30 105.2 0.1 1.6e-11 45.0 0.0 3.8 3 0 0 3 3 3 3 GAF domain GAF_2 PF13185.6 RLN54571.1 - 6.4e-24 84.8 0.0 1.4e-10 41.6 0.0 3.5 3 0 0 3 3 3 3 GAF domain GAF_3 PF13492.6 RLN54571.1 - 8e-09 35.9 0.0 0.019 15.3 0.0 4.1 3 1 0 3 3 3 2 GAF domain DUF3376 PF11856.8 RLN54571.1 - 0.07 12.1 0.9 0.14 11.1 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) HD PF01966.22 RLN54571.1 - 0.11 12.8 1.0 0.31 11.2 0.9 1.9 1 1 0 1 1 1 0 HD domain PP2C PF00481.21 RLN54572.1 - 1.4e-32 113.4 0.0 2.1e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 RLN54572.1 - 1.1e-06 28.7 0.0 0.029 14.3 0.0 3.1 2 1 1 3 3 3 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 RLN54572.1 - 0.00013 21.7 0.0 0.0007 19.3 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C Ank_4 PF13637.6 RLN54597.1 - 6.9e-15 55.2 4.7 0.00027 21.4 0.0 5.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN54597.1 - 4.1e-14 52.9 0.2 0.00059 20.4 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN54597.1 - 7.6e-08 32.5 4.4 0.18 12.2 0.0 5.9 1 1 6 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN54597.1 - 4.2e-07 29.8 0.4 8 7.4 0.0 6.4 7 0 0 7 7 7 1 Ankyrin repeat Ank_2 PF12796.7 RLN54598.1 - 1.9e-20 73.3 0.6 1.7e-09 38.1 0.5 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN54598.1 - 6.6e-17 61.7 6.3 0.0013 19.3 0.1 5.6 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN54598.1 - 1.7e-10 40.9 5.6 0.085 13.2 0.0 6.7 2 1 5 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN54598.1 - 2.4e-10 39.7 0.5 3 8.7 0.0 7.7 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 RLN54598.1 - 1.4 9.5 4.0 60 4.3 0.1 3.6 2 1 1 3 3 3 0 Ankyrin repeat EF-hand_1 PF00036.32 RLN54599.1 - 4.5e-77 248.0 40.5 2.2e-06 26.8 0.0 17.3 17 0 0 17 17 17 15 EF hand EF-hand_7 PF13499.6 RLN54599.1 - 3.1e-70 232.6 53.0 4.4e-09 36.7 0.5 9.9 9 1 1 10 10 10 10 EF-hand domain pair EF-hand_6 PF13405.6 RLN54599.1 - 4.6e-59 191.3 46.1 2.6e-05 23.8 0.1 16.6 16 1 1 17 17 17 14 EF-hand domain EF-hand_8 PF13833.6 RLN54599.1 - 2.4e-48 161.8 42.0 5.9e-06 26.0 0.2 15.0 9 6 6 15 15 15 15 EF-hand domain pair EF-hand_5 PF13202.6 RLN54599.1 - 6.5e-37 123.4 22.4 3.7e-05 23.0 0.0 13.7 13 0 0 13 13 13 8 EF hand EF-hand_11 PF08976.11 RLN54599.1 - 7.8e-14 52.4 11.1 0.014 16.3 0.1 7.6 9 0 0 9 9 8 3 EF-hand domain SPARC_Ca_bdg PF10591.9 RLN54599.1 - 1.4e-11 44.7 9.4 1.8 8.9 0.0 7.9 9 0 0 9 9 9 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 RLN54599.1 - 1.3e-09 38.3 16.2 0.023 15.0 0.0 10.3 11 2 0 11 11 11 1 EF-hand domain EF-hand_4 PF12763.7 RLN54599.1 - 2.8e-06 27.2 15.6 2.6 8.0 0.0 9.3 8 1 2 10 10 10 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 RLN54599.1 - 0.0052 17.1 7.5 0.63 10.4 0.0 6.1 7 0 0 7 7 7 1 EF-hand domain p25-alpha PF05517.12 RLN54599.1 - 0.0064 16.7 0.8 13 5.9 0.0 5.8 7 1 0 8 8 8 0 p25-alpha LURAP PF14854.6 RLN54599.1 - 0.0078 16.2 0.2 0.023 14.6 0.0 1.8 2 0 0 2 2 2 1 Leucine rich adaptor protein COR PF16095.5 RLN54599.1 - 0.012 15.5 0.0 10 5.9 0.0 5.1 6 0 0 6 6 6 0 C-terminal of Roc, COR, domain EF-hand_10 PF14788.6 RLN54599.1 - 0.096 12.6 14.5 1.7 8.6 0.2 6.8 7 0 0 7 7 7 0 EF hand Lipocalin_8 PF16585.5 RLN54599.1 - 0.11 12.9 0.1 0.59 10.6 0.0 2.3 2 0 0 2 2 2 0 Lipocalin-like domain Toprim_2 PF13155.6 RLN54599.1 - 1.3 9.5 8.3 34 4.9 0.1 6.2 7 2 0 7 7 7 0 Toprim-like TMEM154 PF15102.6 RLN54600.1 - 5.4e-06 26.4 2.9 5.4e-06 26.4 2.9 4.7 2 1 2 4 4 4 1 TMEM154 protein family Endomucin PF07010.12 RLN54600.1 - 0.00037 20.6 52.8 0.00037 20.6 52.8 2.1 2 0 0 2 2 2 1 Endomucin TMEM51 PF15345.6 RLN54600.1 - 0.0015 18.5 0.7 0.0015 18.5 0.7 2.5 1 1 1 2 2 2 1 Transmembrane protein 51 Baculo_E56 PF04639.12 RLN54600.1 - 0.038 13.3 0.8 0.038 13.3 0.8 1.5 2 0 0 2 2 2 0 Baculoviral E56 protein, specific to ODV envelope Orf78 PF06024.12 RLN54600.1 - 0.041 14.2 0.3 0.36 11.1 0.0 2.4 2 0 0 2 2 2 0 Orf78 (ac78) EphA2_TM PF14575.6 RLN54600.1 - 0.071 14.0 0.0 0.29 12.0 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3290 PF11694.8 RLN54600.1 - 0.19 11.7 1.1 0.86 9.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) CrgA PF06781.12 RLN54600.1 - 0.25 11.4 1.3 1.2 9.3 0.0 2.7 2 1 0 2 2 2 0 Cell division protein CrgA Peptidase_M56 PF05569.11 RLN54600.1 - 6.2 5.9 5.7 5.7 6.0 0.2 2.3 2 0 0 2 2 2 0 BlaR1 peptidase M56 DUF4330 PF14221.6 RLN54600.1 - 10 6.3 14.9 5.6 7.2 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4330) ADH_N PF08240.12 RLN54601.1 - 3.8e-25 87.9 1.6 3.8e-25 87.9 1.6 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN54601.1 - 8e-15 55.0 0.0 1.6e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 RLN54601.1 - 0.00039 19.8 0.2 0.032 13.5 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 RLN54601.1 - 0.0016 17.8 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ank_2 PF12796.7 RLN54602.1 - 1.1e-28 99.6 4.5 1.6e-07 31.8 0.1 3.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN54602.1 - 1.8e-24 85.8 4.9 1.9e-06 28.3 0.0 6.0 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN54602.1 - 2.6e-19 69.0 10.7 0.0059 16.9 0.1 7.4 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN54602.1 - 4.4e-11 42.0 1.7 0.43 11.3 0.0 6.6 5 2 2 7 7 7 2 Ankyrin repeat Ank PF00023.30 RLN54602.1 - 1.8e-05 25.0 0.4 10 6.8 0.0 5.5 3 1 0 3 3 3 1 Ankyrin repeat DUF1843 PF08898.10 RLN54602.1 - 0.00025 21.5 2.2 6 7.5 0.2 4.3 4 1 0 4 4 4 1 Domain of unknown function (DUF1843) DUF3322 PF11795.8 RLN54602.1 - 0.048 13.7 6.9 11 6.0 0.3 4.3 2 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) W2 PF02020.18 RLN54602.1 - 0.11 12.7 1.2 1.8 8.7 0.1 2.8 2 1 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon WD40 PF00400.32 RLN54604.1 - 1.5e-17 63.6 2.2 3.8e-05 24.4 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN54604.1 - 9.3e-10 38.7 0.0 0.0003 21.0 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain NHL PF01436.21 RLN54604.1 - 0.16 12.0 0.4 4.3 7.6 0.0 3.2 3 0 0 3 3 3 0 NHL repeat WD40 PF00400.32 RLN54605.1 - 2.5e-09 37.6 11.7 0.0038 18.0 0.2 7.1 8 1 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN54605.1 - 2.2e-05 24.6 0.1 0.56 10.5 0.0 4.5 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_B562 PF07361.11 RLN54605.1 - 0.11 13.2 0.4 0.26 12.0 0.4 1.6 1 0 0 1 1 1 0 Cytochrome b562 Fez1 PF06818.15 RLN54605.1 - 1 9.8 7.5 1.7 9.0 7.5 1.2 1 0 0 1 1 1 0 Fez1 GAS PF13851.6 RLN54605.1 - 1.1 8.6 13.2 0.2 11.0 0.7 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding LMBR1 PF04791.16 RLN54605.1 - 1.1 8.1 1.9 1.6 7.5 1.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Spc7 PF08317.11 RLN54605.1 - 1.5 7.6 8.5 2.5 6.9 8.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HisKA PF00512.25 RLN54605.1 - 2.1 8.5 6.8 0.33 11.0 0.7 2.6 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Helo_like_N PF17111.5 RLN54605.1 - 4.4 6.6 7.7 2.2 7.6 0.2 3.0 1 1 2 3 3 3 0 Fungal N-terminal domain of STAND proteins ABC2_membrane PF01061.24 RLN54609.1 - 1.2e-36 126.1 25.8 1.2e-36 126.1 25.8 1.8 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN54609.1 - 1.3e-35 122.9 0.2 2.4e-16 60.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN54609.1 - 3.1e-07 30.5 0.0 0.05 13.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN54609.1 - 5.2e-07 29.7 1.8 0.012 15.6 0.5 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 RLN54609.1 - 6.9e-07 29.8 0.4 0.0072 16.7 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 RLN54609.1 - 3.2e-06 26.8 4.7 0.013 15.3 0.6 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN54609.1 - 7.8e-06 26.2 0.2 0.027 14.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 RLN54609.1 - 1.7e-05 24.5 0.4 0.05 13.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 RLN54609.1 - 2.8e-05 23.4 12.4 2.8e-05 23.4 12.4 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein Zeta_toxin PF06414.12 RLN54609.1 - 8.3e-05 22.0 1.5 0.017 14.4 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin AAA_23 PF13476.6 RLN54609.1 - 0.00058 20.4 0.7 0.23 11.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 RLN54609.1 - 0.00078 19.9 0.4 3.6 8.0 0.2 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 RLN54609.1 - 0.001 18.8 0.2 0.81 9.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 RLN54609.1 - 0.002 17.6 0.9 4 6.8 0.2 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 RLN54609.1 - 0.0062 16.1 1.0 0.74 9.4 0.3 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 RLN54609.1 - 0.0089 16.6 0.0 7 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 RLN54609.1 - 0.014 15.4 0.3 2.4 8.2 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 RLN54609.1 - 0.014 15.5 1.7 2.8 8.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 RLN54609.1 - 0.015 15.3 0.4 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_5 PF07728.14 RLN54609.1 - 0.016 15.2 0.4 0.65 10.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 RLN54609.1 - 0.018 14.8 1.1 4.1 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 RLN54609.1 - 0.033 14.3 0.1 4 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 RLN54609.1 - 0.041 13.0 0.3 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) G-alpha PF00503.20 RLN54609.1 - 0.045 12.9 0.1 0.25 10.5 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit RNA_helicase PF00910.22 RLN54609.1 - 0.046 14.1 0.5 7.7 7.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ABC_ATPase PF09818.9 RLN54609.1 - 0.052 12.3 0.8 1.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NACHT PF05729.12 RLN54609.1 - 0.069 13.1 5.2 2.8 7.9 0.2 2.5 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 RLN54609.1 - 0.079 12.7 1.8 4 7.2 0.3 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 RLN54609.1 - 0.12 12.6 0.6 13 6.0 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 RLN54609.1 - 0.12 12.7 0.3 11 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain PDR_assoc PF08370.11 RLN54609.1 - 0.13 12.1 1.9 0.41 10.4 1.9 1.8 1 0 0 1 1 1 0 Plant PDR ABC transporter associated AAA_7 PF12775.7 RLN54609.1 - 0.14 11.7 1.7 0.89 9.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase PF06745.13 RLN54609.1 - 0.18 11.1 1.3 4.8 6.5 0.1 2.5 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.21 RLN54609.1 - 0.21 11.0 2.3 4.2 6.7 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 RLN54609.1 - 0.46 10.7 1.8 28 4.9 1.3 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 RLN54609.1 - 1.9 8.6 5.6 20 5.2 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain ABC2_membrane PF01061.24 RLN54610.1 - 2.3e-31 108.9 30.5 2.3e-31 108.9 30.5 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RLN54610.1 - 1.2e-16 61.5 0.0 1.7e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter PDR_CDR PF06422.12 RLN54610.1 - 1e-05 25.4 4.6 2.5e-05 24.1 0.0 3.2 3 0 0 3 3 3 1 CDR ABC transporter AAA_21 PF13304.6 RLN54610.1 - 1.2e-05 25.2 0.0 0.032 14.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN54610.1 - 0.0026 17.7 0.1 0.005 16.8 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN54610.1 - 0.0039 16.9 0.6 0.0085 15.8 0.6 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN54610.1 - 0.027 14.0 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 RLN54610.1 - 0.051 14.1 0.0 0.078 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RLN54610.1 - 0.21 11.9 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 RLN54610.1 - 0.72 9.3 1.7 14 5.0 0.4 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain FAM220 PF15487.6 RLN54622.1 - 2 8.0 3.7 2.8 7.5 3.7 1.2 1 0 0 1 1 1 0 FAM220 family Cauli_VI PF01693.16 RLN54623.1 - 1.6e-48 162.7 18.4 6.9e-19 67.9 3.7 3.6 3 0 0 3 3 3 3 Caulimovirus viroplasmin RNase_H PF00075.24 RLN54623.1 - 1.5e-26 93.3 0.0 2.9e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 RNase H RimM PF01782.18 RLN54623.1 - 0.16 12.2 0.2 1.8 8.9 0.0 2.5 2 0 0 2 2 2 0 RimM N-terminal domain GRP PF07172.11 RLN54625.1 - 0.0034 18.0 14.7 0.0061 17.2 14.7 1.5 1 1 0 1 1 1 1 Glycine rich protein family TssC PF17541.2 RLN54641.1 - 0.1 11.4 1.3 0.15 10.8 1.3 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB DnaJ PF00226.31 RLN54643.1 - 3.7e-23 81.4 2.6 1.3e-22 79.6 2.6 2.1 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 RLN54643.1 - 1.6e-18 65.2 17.1 0.0058 16.7 0.0 10.4 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 RLN54643.1 - 2.1e-16 58.9 7.8 0.0081 15.9 0.0 9.7 9 2 1 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 RLN54643.1 - 1.5e-14 54.2 18.5 0.0062 17.0 1.7 7.2 4 3 3 8 8 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 RLN54643.1 - 1e-11 44.3 0.8 0.0038 16.9 0.0 6.9 7 0 0 7 7 7 2 TPR repeat TPR_14 PF13428.6 RLN54643.1 - 4.9e-08 33.1 25.7 1.1 10.3 0.8 9.0 4 3 7 11 11 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 RLN54643.1 - 1.4e-07 31.5 18.0 0.0011 19.1 0.4 5.6 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN54643.1 - 1.6e-07 30.9 17.0 1.5 9.2 0.1 9.6 10 2 1 11 11 11 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN54643.1 - 1.9e-05 25.2 23.1 0.25 12.0 1.7 7.2 4 3 2 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN54643.1 - 3.3e-05 23.9 2.4 0.5 10.9 0.0 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat DUF3856 PF12968.7 RLN54643.1 - 0.00014 21.9 3.4 0.018 15.1 0.6 4.0 3 1 1 4 4 4 1 Domain of Unknown Function (DUF3856) TPR_12 PF13424.6 RLN54643.1 - 0.0016 18.7 27.2 0.64 10.3 4.8 6.0 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN54643.1 - 0.012 15.6 13.1 14 6.0 0.0 7.2 8 0 0 8 8 7 0 Tetratricopeptide repeat DHC_N2 PF08393.13 RLN54643.1 - 0.06 12.4 2.1 0.083 12.0 2.1 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 Alkyl_sulf_dimr PF14863.6 RLN54643.1 - 0.1 13.1 7.9 1.3 9.5 0.0 4.3 2 1 2 4 4 4 0 Alkyl sulfatase dimerisation TPR_10 PF13374.6 RLN54643.1 - 0.21 11.5 11.2 17 5.4 0.2 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF627 PF04781.12 RLN54643.1 - 0.5 10.4 9.8 1 9.4 2.5 4.5 3 2 3 6 6 5 0 Protein of unknown function (DUF627) TPR_6 PF13174.6 RLN54643.1 - 1.8 9.3 15.0 19 6.1 0.0 7.1 8 1 0 8 8 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN54643.1 - 7.9 6.8 19.9 0.69 10.2 0.2 4.8 1 1 4 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Neocarzinostat PF00960.18 RLN54645.1 - 0.015 15.3 0.3 0.029 14.4 0.3 1.4 1 0 0 1 1 1 0 Neocarzinostatin family Tho2 PF11262.8 RLN54645.1 - 0.096 11.9 1.4 0.16 11.1 1.4 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 NCKAP5 PF15246.6 RLN54647.1 - 0.0041 16.8 0.6 0.0061 16.2 0.6 1.2 1 0 0 1 1 1 1 Nck-associated protein 5, Peripheral clock protein Flavodoxin_NdrI PF07972.11 RLN54647.1 - 0.053 13.7 0.0 0.47 10.6 0.0 2.3 2 0 0 2 2 2 0 NrdI Flavodoxin like ThiC-associated PF13667.6 RLN54647.1 - 0.16 11.8 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 ThiC-associated domain HAUS-augmin3 PF14932.6 RLN54647.1 - 0.24 11.0 7.8 2.9 7.4 7.8 2.1 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Serine_rich PF08824.10 RLN54647.1 - 0.57 10.2 4.0 2 8.4 4.0 1.8 1 1 0 1 1 1 0 Serine rich protein interaction domain Zn-ribbon_8 PF09723.10 RLN54654.1 - 0.00057 19.9 3.9 0.00057 19.9 3.9 2.3 1 1 1 2 2 2 1 Zinc ribbon domain zf-CHY PF05495.12 RLN54654.1 - 0.0015 19.0 8.5 0.004 17.6 8.5 1.6 1 1 0 1 1 1 1 CHY zinc finger DZR PF12773.7 RLN54654.1 - 0.0028 17.6 5.4 0.0061 16.6 4.4 1.9 1 1 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 RLN54654.1 - 0.0037 16.9 4.7 0.35 10.7 0.1 3.3 3 0 0 3 3 3 1 zinc-ribbon domain zf-RING_4 PF14570.6 RLN54654.1 - 0.0096 15.7 8.1 0.25 11.2 3.9 2.3 2 0 0 2 2 2 2 RING/Ubox like zinc-binding domain zinc_ribbon_10 PF10058.9 RLN54654.1 - 0.018 14.8 4.7 0.1 12.3 1.4 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-dskA_traR PF01258.17 RLN54654.1 - 0.021 14.7 0.2 0.021 14.7 0.2 2.0 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zf_UBZ PF18439.1 RLN54654.1 - 0.023 14.3 5.1 7 6.3 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger SIR2 PF02146.17 RLN54654.1 - 0.068 13.1 0.9 0.088 12.7 0.9 1.2 1 0 0 1 1 1 0 Sir2 family HypA PF01155.19 RLN54654.1 - 0.085 12.9 6.4 0.33 11.0 6.4 1.9 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 RLN54654.1 - 0.14 12.2 8.0 0.63 10.1 0.0 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain BPL_N PF09825.9 RLN54654.1 - 0.17 11.0 0.1 0.19 10.7 0.1 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal zf-C4_Topoisom PF01396.19 RLN54654.1 - 0.18 11.6 7.2 1.7 8.5 0.2 2.8 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_15 PF17032.5 RLN54654.1 - 0.19 12.5 6.4 0.61 10.9 6.4 1.8 1 1 0 1 1 1 0 zinc-ribbon family zf-ribbon_3 PF13248.6 RLN54654.1 - 0.19 11.2 0.1 0.19 11.2 0.1 2.6 3 0 0 3 3 3 0 zinc-ribbon domain LIM PF00412.22 RLN54654.1 - 0.19 12.0 8.5 1.9 8.8 4.5 2.3 1 1 1 2 2 2 0 LIM domain NOB1_Zn_bind PF08772.11 RLN54654.1 - 0.77 10.0 4.6 2.5 8.3 4.6 1.9 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-C2H2 PF00096.26 RLN54654.1 - 0.82 10.2 8.3 2.3 8.9 0.8 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-trcl PF13451.6 RLN54654.1 - 1 9.3 8.3 3.3 7.7 0.3 3.0 2 1 1 3 3 3 0 Probable zinc-ribbon domain Zn_ribbon_SprT PF17283.2 RLN54654.1 - 1.1 9.2 7.1 9.6 6.2 0.1 2.8 2 1 0 2 2 2 0 SprT-like zinc ribbon domain RNA_POL_M_15KD PF02150.16 RLN54654.1 - 1.3 9.0 7.8 1.6 8.7 0.0 3.1 2 1 1 3 3 3 0 RNA polymerases M/15 Kd subunit zf-RRN7 PF11781.8 RLN54654.1 - 2 8.1 7.6 6 6.6 0.4 3.4 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Rhodanese_C PF12368.8 RLN54654.1 - 2.5 8.5 10.1 9.7 6.7 6.0 2.7 1 1 1 2 2 2 0 Rhodanase C-terminal zinc_ribbon_4 PF13717.6 RLN54654.1 - 3.9 7.5 11.6 5.6 7.0 0.5 3.3 3 1 0 3 3 3 0 zinc-ribbon domain XAF1_C PF18608.1 RLN54654.1 - 7.6 6.2 8.9 3.9 7.1 0.1 2.7 2 1 1 3 3 3 0 XIAP-associated factor 1 C-terminal domain zf-C2H2_4 PF13894.6 RLN54654.1 - 8.8 7.5 13.3 3.2 8.9 0.4 3.5 3 1 0 3 3 3 0 C2H2-type zinc finger RhoGEF PF00621.20 RLN54656.1 - 7.9e-67 225.0 0.0 3.4e-35 121.9 0.0 3.3 3 0 0 3 3 3 3 RhoGEF domain PH PF00169.29 RLN54656.1 - 2.9e-18 66.3 0.7 0.00023 21.6 0.0 5.9 5 1 0 5 5 5 3 PH domain FYVE PF01363.21 RLN54656.1 - 7.1e-18 64.5 18.8 4.7e-16 58.7 6.7 3.2 3 0 0 3 3 3 2 FYVE zinc finger PH_13 PF16652.5 RLN54656.1 - 0.00067 19.5 6.0 0.0014 18.4 0.1 4.1 5 1 0 5 5 5 1 Pleckstrin homology domain FYVE_2 PF02318.16 RLN54656.1 - 0.064 13.5 4.4 0.29 11.4 4.4 2.1 1 0 0 1 1 1 0 FYVE-type zinc finger PH_11 PF15413.6 RLN54656.1 - 0.16 12.4 0.0 19 5.7 0.0 3.8 4 0 0 4 4 4 0 Pleckstrin homology domain Ribophorin_II PF05817.14 RLN54657.1 - 4.6e-63 213.8 0.2 6.1e-63 213.4 0.2 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Y_Y_Y PF07495.13 RLN54657.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Y_Y_Y domain Peptidase_S28 PF05577.12 RLN54658.1 - 7.5e-75 252.4 0.0 1.2e-74 251.7 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 RLN54658.1 - 3.3e-06 26.7 0.0 5.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 RLN54658.1 - 0.0087 15.4 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2920 PF11144.8 RLN54658.1 - 0.019 14.1 0.1 0.031 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) UDPGP PF01704.18 RLN54659.1 - 9.4e-17 60.8 0.0 1e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase OrfB_Zn_ribbon PF07282.11 RLN54661.1 - 0.016 15.1 4.3 0.045 13.7 3.5 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-Mss51 PF13824.6 RLN54661.1 - 0.067 13.3 3.1 5 7.3 3.2 2.7 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DZR PF12773.7 RLN54661.1 - 0.081 13.0 0.9 0.2 11.7 0.9 1.6 1 0 0 1 1 1 0 Double zinc ribbon DUF2716 PF10898.8 RLN54661.1 - 0.092 13.1 0.8 0.35 11.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2716) zf-ribbon_3 PF13248.6 RLN54661.1 - 0.46 10.0 7.1 2.4 7.7 0.8 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS91 PF14319.6 RLN54661.1 - 0.59 10.2 6.9 0.34 11.0 2.5 2.5 1 1 1 2 2 2 0 Transposase zinc-binding domain YhfH PF14149.6 RLN54661.1 - 1.5 8.9 6.8 1.5 8.9 0.2 2.6 1 1 1 2 2 2 0 YhfH-like protein Zn_Tnp_IS1595 PF12760.7 RLN54661.1 - 2.2 8.3 4.9 12 6.0 4.9 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.6 RLN54661.1 - 2.9 7.7 5.6 10 6.0 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain SET PF00856.28 RLN54672.1 - 1.5e-10 41.7 0.1 7.8e-10 39.4 0.1 2.1 1 1 0 1 1 1 1 SET domain Enkurin PF13864.6 RLN54673.1 - 7.7e-24 84.0 0.7 7.7e-24 84.0 0.7 2.1 2 0 0 2 2 2 1 Calmodulin-binding Foamy_virus_ENV PF03408.14 RLN54673.1 - 0.16 9.8 0.1 0.24 9.2 0.1 1.2 1 0 0 1 1 1 0 Foamy virus envelope protein SBDS_C PF09377.10 RLN54674.1 - 1.3e-31 109.0 0.1 3.5e-31 107.6 0.1 1.7 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 RLN54674.1 - 8.8e-30 102.6 1.0 1.5e-29 101.9 1.0 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein HydF_dimer PF18128.1 RLN54674.1 - 0.12 12.4 0.0 8.8 6.5 0.0 2.5 1 1 1 2 2 2 0 Hydrogen maturase F dimerization domain Ribosomal_60s PF00428.19 RLN54674.1 - 0.83 10.3 6.9 0.26 11.9 0.5 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein PAS_3 PF08447.12 RLN54686.1 - 3.1e-09 37.0 0.0 6.5e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 RLN54686.1 - 1e-06 28.7 0.2 2.7e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 PAS fold bZIP_2 PF07716.15 RLN54686.1 - 0.00013 22.0 2.4 0.00024 21.1 2.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 RLN54686.1 - 0.00014 21.8 5.4 0.00024 21.1 5.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor Peroxidase_2 PF01328.17 RLN54687.1 - 2e-50 172.0 0.0 2.3e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 GshA PF08886.11 RLN54687.1 - 0.14 10.7 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase Arb2 PF09757.9 RLN54688.1 - 6e-06 25.6 0.0 1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain TetR_C_6 PF13977.6 RLN54688.1 - 0.17 12.1 3.6 18 5.6 0.0 3.0 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal DUF4279 PF14106.6 RLN54688.1 - 0.62 10.3 6.5 13 6.0 2.8 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4279) Fib_alpha PF08702.10 RLN54688.1 - 2 8.6 18.6 2.2 8.4 4.2 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PX PF00787.24 RLN54689.1 - 0.041 13.9 2.1 0.58 10.2 0.1 3.0 3 0 0 3 3 3 0 PX domain Adaptin_binding PF10199.9 RLN54689.1 - 0.081 13.5 24.1 0.18 12.4 17.7 3.7 3 1 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 GvpO PF05800.11 RLN54689.1 - 0.45 10.5 4.2 1.3 9.1 3.2 2.4 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpO GAGA_bind PF06217.12 RLN54689.1 - 4.2 7.6 21.1 1.4 9.2 13.3 2.4 2 0 0 2 2 2 0 GAGA binding protein-like family Ion_trans PF00520.31 RLN54690.1 - 3.1e-96 321.4 88.8 7.1e-27 94.2 6.7 4.5 5 0 0 5 5 5 4 Ion transport protein GPHH PF16905.5 RLN54690.1 - 4.4e-10 39.2 0.1 5.6e-09 35.6 0.0 2.4 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 RLN54690.1 - 0.57 8.8 77.9 0.017 13.8 1.0 9.1 7 3 1 9 9 9 0 Polycystin cation channel Carb_anhydrase PF00194.21 RLN54691.1 - 1.5e-40 139.4 2.6 1.7e-39 135.9 0.0 3.4 2 1 0 2 2 2 1 Eukaryotic-type carbonic anhydrase PLAC9 PF15205.6 RLN54691.1 - 2.8 8.4 4.1 66 4.0 1.2 3.5 2 0 0 2 2 2 0 Placenta-specific protein 9 Pirin PF02678.16 RLN54692.1 - 5.1e-29 100.4 0.0 1.1e-28 99.3 0.0 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 RLN54692.1 - 5.4e-27 94.2 0.0 1.4e-26 92.8 0.0 1.7 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin_C_2 PF17954.1 RLN54692.1 - 0.079 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain DUF1877 PF08974.10 RLN54692.1 - 0.18 11.9 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) Peroxidase_2 PF01328.17 RLN54693.1 - 1.3e-50 172.6 0.0 1.5e-50 172.4 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Myb_DNA-binding PF00249.31 RLN54694.1 - 1.4e-11 44.4 0.1 2.7e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN54694.1 - 0.05 13.9 0.3 0.096 12.9 0.3 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain RuvX PF03652.15 RLN54694.1 - 0.064 13.6 1.0 0.93 9.9 0.5 2.4 2 0 0 2 2 2 0 Holliday junction resolvase MAS20 PF02064.15 RLN54694.1 - 0.91 9.6 4.1 0.47 10.6 0.4 2.0 2 0 0 2 2 2 0 MAS20 protein import receptor Pyridoxal_deC PF00282.19 RLN54708.1 - 4.7e-60 203.3 0.0 6e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain MS_channel PF00924.18 RLN54733.1 - 1.3e-09 37.9 0.3 1.3e-09 37.9 0.3 1.5 2 0 0 2 2 2 1 Mechanosensitive ion channel Exo_endo_phos PF03372.23 RLN54734.1 - 8.9e-09 35.2 0.2 1.7e-08 34.3 0.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Dicty_CAR PF05462.11 RLN54734.1 - 0.0017 17.5 11.6 0.0037 16.5 11.6 1.4 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 RLN54734.1 - 0.12 11.7 4.3 0.23 10.8 4.3 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Glyco_hydro_10 PF00331.20 RLN54748.1 - 7.4e-53 179.8 0.9 8.7e-53 179.5 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 PHC2_SAM_assoc PF16616.5 RLN54748.1 - 4 8.3 8.0 9.6 7.0 4.5 2.1 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 AAA_5 PF07728.14 RLN54749.1 - 3.7e-40 137.1 0.1 3.5e-25 88.6 0.0 3.9 3 1 1 4 4 4 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RLN54749.1 - 0.00034 21.1 2.4 0.98 9.8 0.1 3.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_lid_7 PF17867.1 RLN54749.1 - 0.059 13.6 0.2 0.25 11.6 0.2 2.1 1 0 0 1 1 1 0 Midasin AAA lid domain AAA_28 PF13521.6 RLN54749.1 - 0.064 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RLN54749.1 - 0.12 12.9 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 RLN54749.1 - 0.13 11.7 0.0 27 4.1 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 RLN54749.1 - 0.17 12.2 1.0 2.8 8.2 0.1 3.4 2 2 0 2 2 2 0 AAA domain Pkinase_Tyr PF07714.17 RLN54769.1 - 9.3e-44 149.6 0.0 7.3e-43 146.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RLN54769.1 - 1.7e-39 135.8 0.0 4e-38 131.3 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Arm PF00514.23 RLN54769.1 - 3.4e-22 77.7 8.6 4.6e-05 23.3 0.0 7.4 8 0 0 8 8 8 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN54769.1 - 9.5e-08 32.4 12.1 8.1e-05 23.0 0.2 6.1 4 2 3 7 7 7 3 HEAT-like repeat HEAT PF02985.22 RLN54769.1 - 7.8e-05 22.6 1.3 1.9 9.0 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 RLN54769.1 - 0.00057 20.2 19.7 0.11 12.9 1.7 4.5 2 2 4 6 6 6 4 HEAT repeats Pkinase_fungal PF17667.1 RLN54769.1 - 0.03 13.1 0.0 0.052 12.3 0.0 1.4 1 1 0 1 1 1 0 Fungal protein kinase T3SS_ExsE PF18286.1 RLN54769.1 - 0.21 11.5 4.6 16 5.5 0.1 4.4 4 0 0 4 4 4 0 Type III secretion system ExsE HEAT_PBS PF03130.16 RLN54769.1 - 2.1 9.3 17.1 22 6.1 0.3 6.8 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat FYVE PF01363.21 RLN54874.1 - 8.3e-13 48.3 6.4 1.9e-12 47.1 6.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN54874.1 - 0.0019 18.4 2.8 0.0019 18.4 2.8 2.0 2 0 0 2 2 2 1 FYVE-type zinc finger zf-B_box PF00643.24 RLN54874.1 - 0.9 9.7 10.2 0.25 11.5 6.2 2.2 2 0 0 2 2 2 0 B-box zinc finger FYVE PF01363.21 RLN54875.1 - 4.5e-14 52.3 4.1 9.2e-14 51.3 4.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN54875.1 - 0.025 14.8 1.2 0.025 14.8 1.2 2.1 3 0 0 3 3 3 0 FYVE-type zinc finger LCM PF04072.14 RLN54876.1 - 2.3e-31 109.2 0.0 1.3e-30 106.7 0.0 2.1 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase PPV_E1_N PF00524.18 RLN54877.1 - 4.5 7.7 9.6 17 5.9 3.6 2.6 2 0 0 2 2 2 0 E1 Protein, N terminal domain Metallophos_C PF14008.6 RLN54878.1 - 3.5e-11 43.8 0.2 9.9e-11 42.3 0.2 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 RLN54878.1 - 1.5e-09 38.3 2.1 2.1e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 RLN54878.1 - 8.7e-07 29.6 1.6 1.3e-06 29.1 0.4 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase PhoD_N PF16655.5 RLN54878.1 - 0.044 14.3 0.2 0.14 12.7 0.0 2.0 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain PNK3P PF08645.11 RLN54878.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase EMC3_TMCO1 PF01956.16 RLN54879.1 - 1.8e-17 63.6 4.3 3e-17 62.9 4.3 1.4 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF4199 PF13858.6 RLN54879.1 - 0.018 15.4 1.3 0.035 14.5 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) zf-CDGSH PF09360.10 RLN54880.1 - 5.4e-11 42.5 0.4 9.1e-11 41.8 0.4 1.4 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type MitoNEET_N PF10660.9 RLN54880.1 - 4.5e-10 39.4 0.3 6.2e-10 39.0 0.3 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus Pkinase PF00069.25 RLN54881.1 - 1.2e-51 175.6 0.0 1.6e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN54881.1 - 1.2e-44 152.5 0.0 1.6e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN54881.1 - 0.0077 15.6 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RLN54881.1 - 0.022 13.7 0.0 0.038 12.9 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 RLN54881.1 - 0.072 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Band_7 PF01145.25 RLN54883.1 - 1.3e-18 67.6 0.0 1.7e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Pkinase PF00069.25 RLN54884.1 - 1.1e-53 182.3 0.0 1.6e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN54884.1 - 3e-43 148.0 0.0 3.9e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN54884.1 - 0.027 13.3 0.2 0.045 12.5 0.2 1.5 1 1 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 RLN54884.1 - 0.065 12.2 0.0 0.11 11.4 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 RLN54885.1 - 3.2e-37 128.3 0.0 4.1e-37 128.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN54885.1 - 1.7e-35 122.6 0.0 2.2e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.17 RLN54886.1 - 9.4e-23 80.8 0.0 6.6e-09 35.4 0.0 4.1 2 2 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 RLN54886.1 - 5.8e-21 75.0 0.0 5.6e-08 32.5 0.0 4.8 4 2 1 5 5 5 3 Protein kinase domain PI3_PI4_kinase PF00454.27 RLN54888.1 - 5.9e-55 186.8 0.0 9.7e-55 186.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pkinase PF00069.25 RLN54888.1 - 2.7e-23 82.7 0.0 2e-22 79.8 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN54888.1 - 2.4e-22 79.4 0.0 5.1e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FATC PF02260.20 RLN54888.1 - 8.8e-06 25.4 0.0 1.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 FATC domain CHASE3 PF05227.13 RLN54888.1 - 2.3 8.1 5.8 7.5 6.5 0.1 2.9 2 0 0 2 2 2 0 CHASE3 domain Band_7 PF01145.25 RLN54890.1 - 5.5e-26 91.7 0.1 1.2e-25 90.5 0.1 1.6 2 1 0 2 2 2 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 RLN54890.1 - 0.00041 19.5 1.7 0.00057 19.0 1.7 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial DUF3255 PF11631.8 RLN54890.1 - 0.074 12.9 0.0 0.78 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3255) PBP1_TM PF14812.6 RLN54891.1 - 0.025 14.9 8.5 0.032 14.6 8.5 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 RLN54891.1 - 0.063 12.6 6.3 0.067 12.5 6.3 1.0 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 RLN54891.1 - 0.069 12.3 8.7 0.075 12.2 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA_pol_3_Rpc31 PF11705.8 RLN54891.1 - 0.89 9.8 11.4 0.92 9.7 11.4 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RRN3 PF05327.11 RLN54891.1 - 2.4 6.6 8.4 2.7 6.4 8.4 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 RLN54891.1 - 4 5.4 8.7 4.4 5.3 8.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi His_Phos_1 PF00300.22 RLN54907.1 - 2.9e-10 40.2 0.9 2.5e-05 24.1 0.0 3.5 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 1) Pyridoxal_deC PF00282.19 RLN54909.1 - 1.7e-16 59.9 0.0 2.8e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 RLN54909.1 - 1.5e-05 24.1 0.1 6.1e-05 22.1 0.1 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 RLN54909.1 - 0.0032 16.7 0.0 0.013 14.7 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II Ceramidase_alk PF04734.13 RLN54925.1 - 2.1e-161 538.0 0.1 5e-161 536.8 0.1 1.5 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 RLN54925.1 - 1.4e-41 142.2 0.0 2.2e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Tachystatin_B PF11478.8 RLN54926.1 - 0.17 11.9 3.9 0.49 10.4 3.9 1.7 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B WD40 PF00400.32 RLN54927.1 - 1.3e-51 171.4 16.9 3.1e-07 31.0 0.0 11.5 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN54927.1 - 1.8e-18 66.6 0.5 0.0031 17.8 0.0 7.4 4 3 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RLN54927.1 - 5.4e-08 32.9 0.1 0.14 12.0 0.0 4.5 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 RLN54927.1 - 3.4e-05 23.0 0.1 0.56 9.1 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 RLN54927.1 - 0.00019 20.9 0.0 0.031 13.6 0.0 2.5 2 0 0 2 2 2 2 WD40-like domain Nbas_N PF15492.6 RLN54927.1 - 0.0017 17.7 0.3 0.46 9.8 0.0 3.4 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 RLN54927.1 - 0.0025 17.7 2.9 5.7 7.0 0.0 4.6 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Frtz PF11768.8 RLN54927.1 - 0.0071 14.7 0.0 7.8 4.7 0.0 3.1 3 0 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz Coatomer_WDAD PF04053.14 RLN54927.1 - 0.023 13.7 0.0 3.1 6.7 0.0 3.1 2 2 2 4 4 4 0 Coatomer WD associated region IKI3 PF04762.12 RLN54927.1 - 0.027 12.5 0.3 0.98 7.3 0.0 3.1 1 1 2 3 3 3 0 IKI3 family WD40 PF00400.32 RLN54928.1 - 2.3e-15 56.7 16.2 0.00063 20.5 0.2 8.2 8 0 0 8 8 8 3 WD domain, G-beta repeat BBS2_Mid PF14783.6 RLN54928.1 - 0.089 12.8 0.2 5.4 7.1 0.0 3.5 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.6 RLN54928.1 - 1.2 9.8 4.1 44 4.8 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain PAC4 PF16093.5 RLN54930.1 - 2.8e-11 43.4 0.1 5.2e-11 42.6 0.0 1.5 2 0 0 2 2 2 1 Proteasome assembly chaperone 4 Asn_synthase PF00733.21 RLN54930.1 - 0.026 14.2 0.0 0.031 13.9 0.0 1.0 1 0 0 1 1 1 0 Asparagine synthase DUF874 PF05917.11 RLN54931.1 - 0.075 12.1 0.0 0.09 11.8 0.0 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Corona_nucleoca PF00937.18 RLN54932.1 - 0.27 10.3 6.2 0.49 9.4 6.2 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Ceramidase_alk PF04734.13 RLN54933.1 - 9.6e-162 539.2 0.3 2.2e-161 537.9 0.3 1.5 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 RLN54933.1 - 4.1e-45 153.7 0.0 7e-45 152.9 0.0 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal CBM_19 PF03427.13 RLN54934.1 - 6.2 6.9 7.4 2.3 8.3 1.1 2.8 2 0 0 2 2 2 0 Carbohydrate binding domain (family 19) Macoilin PF09726.9 RLN54934.1 - 7.3 5.0 10.3 10 4.5 10.3 1.1 1 0 0 1 1 1 0 Macoilin family CABIT PF12736.7 RLN54935.1 - 0.017 14.4 0.0 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 Cell-cycle sustaining, positive selection, SMC_N PF02463.19 RLN54936.1 - 5.5e-62 209.1 0.0 9.4e-62 208.3 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 RLN54936.1 - 1.1e-27 96.7 0.0 4e-27 94.8 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 RLN54936.1 - 4.7e-12 46.3 4.2 2.3e-07 30.9 0.0 4.0 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RLN54936.1 - 9.5e-08 32.8 27.8 9.5e-08 32.8 27.8 6.0 2 2 0 3 3 3 1 AAA domain AAA_29 PF13555.6 RLN54936.1 - 4.2e-07 29.6 0.0 9.6e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 RLN54936.1 - 0.00069 20.1 17.7 0.033 14.7 0.5 5.9 4 2 0 4 4 4 1 ABC transporter SbcCD_C PF13558.6 RLN54936.1 - 0.082 13.2 0.0 0.3 11.4 0.0 2.0 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 RLN54936.1 - 8.4 6.7 7.2 16 5.8 0.0 4.4 4 1 0 4 4 4 0 AAA domain Sugar_tr PF00083.24 RLN54947.1 - 2.9e-24 85.8 18.4 1.7e-23 83.2 18.4 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN54947.1 - 5.8e-24 84.7 31.2 1e-18 67.4 19.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 RLN54947.1 - 0.066 12.1 9.4 0.21 10.4 9.3 2.1 2 1 0 2 2 2 0 MFS_1 like family OATP PF03137.20 RLN54947.1 - 4.6 5.4 8.7 1.1e+02 0.9 8.7 2.3 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MMR_HSR1 PF01926.23 RLN54957.1 - 2.7e-14 53.2 0.0 3.7e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RLN54957.1 - 1.4e-10 41.4 0.1 5.6e-10 39.4 0.1 1.8 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 RLN54957.1 - 1e-06 28.3 0.6 1e-05 25.1 0.2 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 RLN54957.1 - 0.0049 16.4 0.0 0.55 9.8 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 RLN54957.1 - 0.008 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_16 PF13191.6 RLN54957.1 - 0.023 15.1 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 RLN54957.1 - 0.076 12.1 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain AAA_22 PF13401.6 RLN54957.1 - 0.081 13.2 0.0 0.27 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 RLN54957.1 - 0.11 12.7 0.0 0.47 10.7 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 RLN54957.1 - 0.12 13.0 0.0 0.33 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Pkinase_Tyr PF07714.17 RLN54958.1 - 1.5e-51 175.2 0.0 1.7e-50 171.7 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RLN54958.1 - 2.1e-43 148.6 0.0 3.5e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain NiFe_hyd_3_EhaA PF17367.2 RLN54958.1 - 0.0084 16.2 0.8 0.11 12.6 0.9 2.6 2 0 0 2 2 2 1 NiFe-hydrogenase-type-3 Eha complex subunit A APH PF01636.23 RLN54958.1 - 0.16 11.8 0.1 0.46 10.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN54958.1 - 0.19 10.6 0.1 6.8 5.5 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain DUF4131 PF13567.6 RLN54958.1 - 0.57 9.8 3.3 1 9.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Glyco_hydro_10 PF00331.20 RLN54962.1 - 2.8e-46 158.1 0.2 3.7e-46 157.7 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 AAA_5 PF07728.14 RLN54962.1 - 1.6e-38 131.8 0.5 1.8e-24 86.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 RLN54962.1 - 0.00035 20.7 0.1 0.0009 19.4 0.1 1.7 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_16 PF13191.6 RLN54962.1 - 0.00095 19.6 2.7 2.7 8.3 1.1 4.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 RLN54962.1 - 0.058 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain FYVE PF01363.21 RLN54978.1 - 0.005 17.0 10.1 0.0095 16.1 10.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-4CXXC_R1 PF10497.9 RLN54978.1 - 0.037 14.2 4.2 0.14 12.4 4.2 2.0 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 FYVE_2 PF02318.16 RLN54978.1 - 0.048 13.9 6.4 0.11 12.7 6.4 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 RLN54979.1 - 4.5e-05 23.5 12.2 9.8e-05 22.4 12.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN54979.1 - 0.037 14.3 6.6 0.14 12.4 6.6 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger K-cyclin_vir_C PF09080.10 RLN54979.1 - 0.1 13.0 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 K cyclin, C terminal ABC2_membrane_3 PF12698.7 RLN54985.1 - 1.2e-39 136.5 19.7 2e-39 135.7 19.7 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 RLN54985.1 - 3.7e-14 53.4 0.3 8.2e-07 29.6 0.3 2.3 1 1 1 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN54985.1 - 4.8e-10 39.7 0.7 3.5e-08 33.6 0.0 2.9 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RLN54985.1 - 0.018 14.8 0.0 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ABC2_membrane_2 PF12679.7 RLN54985.1 - 2.1 7.5 10.9 4.7 6.4 10.9 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein AA_permease_2 PF13520.6 RLN54992.1 - 1e-24 87.2 30.4 1.4e-24 86.8 30.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN54992.1 - 4.3e-14 52.0 19.8 7e-14 51.3 19.8 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3439 PF11921.8 RLN54992.1 - 8.9 6.3 8.9 98 2.9 8.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) NUDE_C PF04880.13 RLN55027.1 - 0.00013 22.5 6.4 0.00013 22.5 6.4 1.9 2 0 0 2 2 2 1 NUDE protein, C-terminal conserved region NST1 PF13945.6 RLN55027.1 - 0.0027 17.9 8.5 0.094 12.8 5.9 2.2 2 0 0 2 2 2 2 Salt tolerance down-regulator Rtf2 PF04641.12 RLN55027.1 - 0.54 9.6 8.6 0.83 9.0 8.6 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger SNF2_N PF00176.23 RLN55028.1 - 4.8e-54 183.4 0.1 3e-53 180.8 0.1 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN55028.1 - 3.5e-16 59.5 0.0 1.1e-15 58.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-PARP PF00645.18 RLN55028.1 - 6.8e-11 42.9 0.1 6.2e-10 39.8 0.0 2.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PHD PF00628.29 RLN55028.1 - 3e-09 36.6 3.1 3e-09 36.6 3.1 3.7 4 0 0 4 4 4 1 PHD-finger zf-C3HC4_3 PF13920.6 RLN55028.1 - 7.5e-07 28.9 5.0 7.5e-07 28.9 5.0 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN55028.1 - 2.5e-06 27.2 5.3 2.5e-06 27.2 5.3 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 RLN55028.1 - 5.2e-06 26.6 0.0 6.4e-05 23.0 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 RLN55028.1 - 6.7e-06 26.3 18.9 0.00023 21.4 5.9 2.8 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 RLN55028.1 - 7.5e-06 25.7 2.9 7.5e-06 25.7 2.9 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN55028.1 - 4.3e-05 23.4 5.4 4.3e-05 23.4 5.4 3.7 5 0 0 5 5 5 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RLN55028.1 - 5e-05 23.2 3.5 5e-05 23.2 3.5 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 RLN55028.1 - 0.00097 19.4 9.8 0.052 13.8 2.0 3.0 2 0 0 2 2 2 2 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 RLN55028.1 - 0.0094 16.1 6.3 0.0094 16.1 6.3 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Ima1_N PF09779.9 RLN55028.1 - 0.035 15.0 1.1 0.035 15.0 1.1 3.4 3 0 0 3 3 3 0 Ima1 N-terminal domain zf-C2HC_2 PF13913.6 RLN55028.1 - 0.14 12.1 0.0 0.14 12.1 0.0 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn_ribbon_17 PF17120.5 RLN55028.1 - 1.7 8.3 9.4 0.53 9.9 0.7 2.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-BED PF02892.15 RLN55028.1 - 2.1 8.4 9.3 1 9.4 0.1 4.1 4 0 0 4 4 4 0 BED zinc finger zf-ANAPC11 PF12861.7 RLN55028.1 - 6.5 6.9 7.4 9.2 6.4 0.8 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger RRM_2 PF04059.12 RLN55029.1 - 9e-45 150.8 0.8 1.4e-44 150.2 0.8 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 zf-B_box PF00643.24 RLN55029.1 - 0.00027 21.0 5.3 0.0006 19.9 5.3 1.6 1 0 0 1 1 1 1 B-box zinc finger Smg4_UPF3 PF03467.15 RLN55029.1 - 0.0038 17.3 0.1 0.008 16.2 0.1 1.5 1 0 0 1 1 1 1 Smg-4/UPF3 family RRM_1 PF00076.22 RLN55029.1 - 0.015 15.1 0.0 0.1 12.4 0.1 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 RLN55029.1 - 0.14 12.4 0.2 0.3 11.3 0.2 1.5 1 0 0 1 1 1 0 BRCA1-associated protein 2 ZZ PF00569.17 RLN55029.1 - 0.17 11.7 3.3 0.39 10.6 3.3 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type zf-HIT PF04438.16 RLN55029.1 - 1.4 8.8 4.2 3 7.8 4.2 1.5 1 0 0 1 1 1 0 HIT zinc finger PriCT_2 PF08707.11 RLN55029.1 - 2.7 8.4 5.7 2.9 8.3 2.1 2.3 2 0 0 2 2 2 0 Primase C terminal 2 (PriCT-2) QRPTase_C PF01729.19 RLN55030.1 - 2e-35 122.0 0.0 4.9e-17 62.2 0.0 2.1 1 1 1 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 RLN55030.1 - 1.1e-16 60.7 0.0 2.8e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain RabGAP-TBC PF00566.18 RLN55031.1 - 0.002 17.8 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain tRNA_synt_1c_R2 PF04557.15 RLN55031.1 - 0.14 13.1 2.4 0.17 12.9 0.3 1.9 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Pup PF05639.11 RLN55031.1 - 1.4 9.9 5.4 3.8 8.5 0.0 3.0 3 0 0 3 3 3 0 Pup-like protein Mut7-C PF01927.16 RLN55032.1 - 1.3e-32 112.9 0.2 1.8e-32 112.5 0.2 1.1 1 0 0 1 1 1 1 Mut7-C RNAse domain DUF1450 PF07293.11 RLN55032.1 - 0.002 17.9 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1450) DUF5615 PF18480.1 RLN55032.1 - 0.0021 17.8 0.0 0.0076 16.0 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5615) DUF572 PF04502.13 RLN55034.1 - 3.6e-57 194.5 0.1 4.3e-57 194.2 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DDE_3 PF13358.6 RLN55035.1 - 6.5e-19 68.1 0.0 1.2e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Exo_endo_phos PF03372.23 RLN55035.1 - 4.3e-13 49.3 0.0 7.1e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-PARP PF00645.18 RLN55035.1 - 1.4e-10 41.8 0.4 3.2e-10 40.7 0.4 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region HTH_32 PF13565.6 RLN55035.1 - 4.8e-06 27.1 0.0 1.1e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 RLN55035.1 - 2.3e-05 24.0 0.3 5.8e-05 22.8 0.3 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 RLN55035.1 - 0.00018 21.6 1.0 0.00041 20.4 1.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 RLN55035.1 - 0.026 14.8 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 Transposase HypF_C PF17788.1 RLN55035.1 - 0.051 14.3 0.0 0.16 12.7 0.0 1.9 1 0 0 1 1 1 0 HypF Kae1-like domain TetR_C_11 PF16859.5 RLN55036.1 - 0.012 15.9 2.8 0.081 13.2 0.2 3.7 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain DUF3489 PF11994.8 RLN55036.1 - 0.13 12.3 0.3 0.42 10.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3489) MCM PF00493.23 RLN55043.1 - 8.2e-101 335.8 0.1 1.1e-100 335.3 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RLN55043.1 - 7e-39 132.6 0.1 1.2e-38 131.8 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 RLN55043.1 - 6.5e-18 65.2 0.3 1.5e-17 64.0 0.3 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 RLN55043.1 - 8.1e-10 38.4 0.0 1.5e-08 34.2 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RLN55043.1 - 0.00036 20.6 0.0 0.00077 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 RLN55043.1 - 0.0029 17.3 0.0 0.0062 16.3 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 RLN55043.1 - 0.0049 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MULE PF10551.9 RLN55051.1 - 9.4e-10 38.8 0.1 1.7e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 MULE transposase domain Kinesin PF00225.23 RLN55053.1 - 6.3e-82 275.2 0.2 1e-81 274.5 0.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN55053.1 - 6.5e-13 48.9 0.0 9.7e-12 45.1 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding Myc_N PF01056.18 RLN55053.1 - 0.39 10.6 3.8 0.75 9.6 3.8 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Cnn_1N PF07989.11 RLN55053.1 - 9.7 6.4 12.2 0.15 12.2 1.6 3.2 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 BolA PF01722.18 RLN55054.1 - 4.8e-10 39.6 0.0 8e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein MULE PF10551.9 RLN55055.1 - 4.6e-08 33.4 2.4 4.2e-06 27.1 2.4 2.9 1 1 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 RLN55055.1 - 0.0019 18.0 0.2 0.004 16.9 0.2 1.6 1 0 0 1 1 1 1 Transposase Cupin_6 PF12852.7 RLN55055.1 - 0.032 13.9 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Cupin Sugar_tr PF00083.24 RLN55056.1 - 1.5e-13 50.4 0.7 7.9e-10 38.2 0.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter HELP PF03451.14 RLN55072.1 - 4.4e-09 36.1 0.0 9.4e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 HELP motif WD40 PF00400.32 RLN55072.1 - 8.9e-08 32.7 15.6 0.93 10.5 0.6 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN55072.1 - 0.0036 17.6 0.0 2.4 8.5 0.0 4.2 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 RLN55072.1 - 0.3 9.4 0.1 4.7 5.4 0.2 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF455 PF04305.14 RLN55100.1 - 2.8e-80 269.4 0.2 5.6e-80 268.5 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF455) Glyco_trans_1_4 PF13692.6 RLN55100.1 - 1.4e-16 61.1 0.0 5e-16 59.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 RLN55100.1 - 0.058 13.4 0.0 2 8.4 0.0 2.5 2 0 0 2 2 2 0 Glycosyltransferase Family 4 ABC2_membrane PF01061.24 RLN55101.1 - 6.5e-37 127.0 21.6 8.9e-37 126.5 21.6 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 RLN55101.1 - 2.5e-08 33.5 8.1 2.5e-08 33.5 8.1 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein PDR_CDR PF06422.12 RLN55101.1 - 4.3e-08 33.0 0.0 2e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 CDR ABC transporter DUF4705 PF15788.5 RLN55101.1 - 0.052 13.8 0.3 0.75 10.1 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4705) Deltaretro_Tax PF05599.11 RLN55101.1 - 0.11 13.1 0.3 0.61 10.6 0.0 2.2 2 0 0 2 2 2 0 Deltaretrovirus Tax protein Pax2_C PF12403.8 RLN55101.1 - 0.12 12.5 0.3 0.8 9.8 0.0 2.1 2 0 0 2 2 2 0 Paired-box protein 2 C terminal ABC2_membrane PF01061.24 RLN55102.1 - 7.6e-34 117.0 24.9 1.1e-33 116.5 24.9 1.2 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN55102.1 - 2.3e-08 33.8 0.0 2.3e-08 33.8 0.0 2.6 3 0 0 3 3 3 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 RLN55102.1 - 1e-07 31.4 9.9 1e-07 31.4 9.9 1.5 1 1 1 2 2 2 1 ABC-2 family transporter protein Sugar_tr PF00083.24 RLN55124.1 - 1.7e-06 27.2 0.0 2.2e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN55124.1 - 0.006 15.6 0.0 0.0077 15.2 0.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily GAGE PF05831.11 RLN55124.1 - 0.18 12.3 0.9 0.31 11.6 0.9 1.3 1 0 0 1 1 1 0 GAGE protein Histidinol_dh PF00815.20 RLN55140.1 - 1.4e-107 360.3 4.2 1.6e-107 360.1 4.2 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase OAD_gamma PF04277.13 RLN55141.1 - 0.074 13.7 0.9 0.23 12.1 0.0 2.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF5644 PF18712.1 RLN55141.1 - 0.17 11.9 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5644) DUF1542 PF07564.11 RLN55141.1 - 2.8 8.1 5.3 2.3 8.4 1.7 2.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1542) Histidinol_dh PF00815.20 RLN55142.1 - 4e-05 22.8 0.0 6.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase DUF1556 PF07590.11 RLN55142.1 - 0.1 12.9 1.1 0.3 11.4 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1556) DUF3613 PF12266.8 RLN55143.1 - 0.12 12.2 0.6 24 4.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3613) Ycf4 PF02392.16 RLN55143.1 - 0.72 9.4 12.7 4.1 6.9 2.6 2.6 2 0 0 2 2 2 0 Ycf4 AMP-binding PF00501.28 RLN55150.1 - 3.9e-70 236.6 0.0 4.7e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN55150.1 - 0.00068 20.6 0.0 0.0015 19.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF5115 PF17142.4 RLN55150.1 - 0.13 11.9 0.2 0.4 10.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5115) Peptidase_C1 PF00112.23 RLN55169.1 - 1.6e-40 139.5 8.4 9.5e-40 137.0 7.0 2.4 2 1 0 2 2 2 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RLN55169.1 - 0.0016 17.3 0.7 1.1 8.0 0.1 2.4 2 0 0 2 2 2 2 Peptidase C1-like family Phage_holin_2_1 PF04971.12 RLN55169.1 - 0.03 14.3 1.6 0.03 14.3 1.6 2.8 2 1 0 2 2 2 0 Bacteriophage P21 holin S Phage_holin_2_2 PF10746.9 RLN55169.1 - 0.059 13.0 0.6 0.14 11.9 0.6 1.6 1 0 0 1 1 1 0 Phage holin T7 family, holin superfamily II Malate_synthase PF01274.22 RLN55218.1 - 2.6e-66 224.0 0.0 1.7e-59 201.5 0.0 2.0 1 1 1 2 2 2 2 Malate synthase DUF3047 PF11249.8 RLN55218.1 - 0.21 11.0 0.9 2.9 7.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3047) SNF2_N PF00176.23 RLN55219.1 - 1.4e-63 214.7 0.1 2.3e-63 214.0 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN55219.1 - 3.4e-19 69.2 0.0 1.4e-18 67.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 RLN55219.1 - 2.3e-09 36.8 0.0 4.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 RLN55219.1 - 5.6e-08 33.0 0.0 2.8e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RLN55219.1 - 0.0002 21.2 0.0 0.00049 19.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase NYD-SP28_assoc PF14775.6 RLN55220.1 - 7.1 6.8 9.0 25 5.1 0.1 3.7 3 1 0 3 3 3 0 Sperm tail C-terminal domain DinB_2 PF12867.7 RLN55221.1 - 0.11 13.0 0.3 0.4 11.2 0.3 2.0 1 0 0 1 1 1 0 DinB superfamily BT1 PF03092.16 RLN55235.1 - 3.7e-15 55.1 6.8 4.6e-12 44.9 0.9 2.1 1 1 1 2 2 2 2 BT1 family PUCC PF03209.15 RLN55235.1 - 0.0022 17.1 2.2 0.0052 15.8 2.1 1.5 1 1 0 1 1 1 1 PUCC protein DUF4464 PF14713.6 RLN55235.1 - 0.17 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4464) FLgD_tudor PF13861.6 RLN55242.1 - 0.71 10.2 9.9 3.3 8.0 2.7 2.8 2 2 1 3 3 3 0 FlgD Tudor-like domain DSPn PF14671.6 RLN55243.1 - 1.9e-32 112.7 0.0 2.9e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 RLN55243.1 - 1.5e-13 50.7 0.0 4.1e-13 49.3 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RLN55243.1 - 8.6e-06 25.5 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 RLN55243.1 - 1.9e-05 24.8 0.0 2.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 RLN55243.1 - 0.011 15.7 0.1 0.017 15.1 0.1 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Ras PF00071.22 RLN55244.1 - 4.9e-32 110.8 0.0 6.6e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN55244.1 - 1.7e-16 60.6 0.0 2.3e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN55244.1 - 5.3e-06 26.0 0.0 9.3e-06 25.2 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RLN55244.1 - 0.005 16.9 0.0 0.0078 16.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 RLN55244.1 - 0.022 15.3 0.0 0.036 14.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 RLN55244.1 - 0.03 14.7 0.2 0.053 13.9 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain DLIC PF05783.11 RLN55244.1 - 0.043 12.6 0.0 0.076 11.8 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_22 PF13401.6 RLN55244.1 - 0.065 13.5 0.0 0.35 11.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain FLgD_tudor PF13861.6 RLN55245.1 - 1.7 9.0 8.3 7.1 7.0 2.9 2.6 1 1 1 2 2 2 0 FlgD Tudor-like domain tRNA-synt_2 PF00152.20 RLN55247.1 - 1.1e-97 327.0 0.0 1.3e-97 326.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RLN55247.1 - 6e-13 48.6 0.1 1.3e-12 47.6 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GAD PF02938.14 RLN55247.1 - 8.9e-12 45.1 0.3 1.8e-11 44.1 0.3 1.5 1 0 0 1 1 1 1 GAD domain tRNA-synt_2b PF00587.25 RLN55247.1 - 0.0057 16.6 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 RLN55247.1 - 0.12 11.8 0.0 0.53 9.7 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) WD40 PF00400.32 RLN55248.1 - 3.1e-06 27.8 0.3 0.017 16.0 0.1 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN55248.1 - 0.14 12.5 0.0 7 7.0 0.0 3.0 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN55248.1 - 0.16 10.6 0.2 0.5 8.9 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 RRM_1 PF00076.22 RLN55266.1 - 5.1e-25 87.1 0.7 5.7e-17 61.3 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RLN55266.1 - 0.00037 20.1 0.0 0.007 16.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN55266.1 - 0.0058 16.7 0.1 4.6 7.4 0.0 3.1 2 1 0 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 RLN55266.1 - 0.12 12.2 0.0 0.7 9.8 0.0 1.9 2 0 0 2 2 2 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 RLN55266.1 - 0.13 12.3 0.7 4.9 7.2 0.1 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 RLN55266.1 - 0.24 11.6 0.6 6.6 6.9 0.0 2.4 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF1697 PF08002.11 RLN55276.1 - 2.9e-22 79.6 1.0 8.9e-22 78.0 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1697) ASFV_J13L PF05568.11 RLN55276.1 - 2.8 7.7 6.4 4.5 7.0 6.4 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein Helicase_C PF00271.31 RLN55277.1 - 1.9e-21 76.5 0.0 3.6e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RLN55277.1 - 3.3e-15 56.3 0.1 5.3e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Arm_3 PF16186.5 RLN55278.1 - 3e-19 68.3 2.0 5e-19 67.6 2.0 1.3 1 0 0 1 1 1 1 Atypical Arm repeat Laminin_G_3 PF13385.6 RLN55278.1 - 0.056 13.6 0.0 0.084 13.0 0.0 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Thr_synth_N PF14821.6 RLN55279.1 - 1.2e-26 92.7 0.0 3e-26 91.4 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 RLN55279.1 - 3.5e-20 72.6 3.4 2.1e-18 66.8 0.1 3.0 1 1 1 2 2 2 1 Pyridoxal-phosphate dependent enzyme Ras PF00071.22 RLN55280.1 - 1.8e-57 193.5 0.1 2.5e-57 193.0 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN55280.1 - 2.4e-32 111.6 0.1 4.4e-32 110.8 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN55280.1 - 1.4e-14 53.9 0.0 2e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RLN55280.1 - 3.7e-07 29.7 0.0 5.3e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RLN55280.1 - 5e-06 26.6 0.0 9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RLN55280.1 - 0.00079 19.0 0.1 0.0034 16.9 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RLN55280.1 - 0.0024 17.8 0.1 0.051 13.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_5 PF07728.14 RLN55280.1 - 0.0053 16.8 0.0 0.013 15.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 RLN55280.1 - 0.02 15.0 0.1 0.04 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RLN55280.1 - 0.021 15.2 0.0 0.038 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 RLN55280.1 - 0.037 13.9 0.0 0.079 12.9 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 RLN55280.1 - 0.069 12.7 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 RLN55280.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein DHC_N1 PF08385.12 RLN55292.1 - 2.6e-186 620.6 0.4 2.6e-186 620.6 0.4 4.0 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 RLN55292.1 - 8.5e-139 462.1 1.3 3.9e-75 252.8 0.0 3.6 4 0 0 4 4 4 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN55292.1 - 4.7e-115 384.9 14.5 4.7e-115 384.9 14.5 3.8 4 1 1 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RLN55292.1 - 2.5e-91 305.6 0.0 1.5e-90 303.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RLN55292.1 - 2.3e-79 265.6 1.9 2.3e-79 265.6 1.9 3.0 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 RLN55292.1 - 2.1e-69 232.7 0.3 1.1e-62 210.7 0.1 3.9 3 0 0 3 3 3 2 P-loop containing dynein motor region MT PF12777.7 RLN55292.1 - 5.7e-68 229.5 13.2 5.7e-68 229.5 13.2 2.3 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 RLN55292.1 - 1.7e-24 86.3 0.3 6.1e-10 39.2 0.0 5.8 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 RLN55292.1 - 2.9e-21 75.9 0.0 1.4e-20 73.7 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RLN55292.1 - 4.1e-20 71.9 0.1 1.5e-19 70.0 0.1 2.1 1 0 0 1 1 1 1 AAA+ lid domain Dynein_heavy PF03028.15 RLN55292.1 - 7e-20 71.3 0.0 9.1e-19 67.7 0.0 3.2 3 0 0 3 3 1 1 Dynein heavy chain region D6 P-loop domain AAA PF00004.29 RLN55292.1 - 8.6e-09 35.9 0.1 0.23 11.9 0.0 5.3 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RLN55292.1 - 6.9e-08 33.1 0.5 0.043 14.4 0.0 6.1 6 0 0 6 6 4 1 AAA domain AAA_16 PF13191.6 RLN55292.1 - 8.4e-07 29.5 2.9 0.0092 16.4 0.0 5.6 5 0 0 5 5 4 1 AAA ATPase domain AAA_22 PF13401.6 RLN55292.1 - 6.5e-06 26.5 0.1 0.011 16.0 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 RLN55292.1 - 1.5e-05 24.8 3.6 0.23 11.1 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.6 RLN55292.1 - 1.6e-05 25.3 0.9 0.072 13.4 0.0 4.2 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 RLN55292.1 - 8.2e-05 22.9 0.6 4 7.9 0.0 4.4 4 0 0 4 4 3 1 RNA helicase AAA_25 PF13481.6 RLN55292.1 - 0.00011 21.9 0.3 0.73 9.4 0.0 3.9 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 RLN55292.1 - 0.0002 21.3 0.1 0.15 12.0 0.0 4.1 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_28 PF13521.6 RLN55292.1 - 0.00022 21.5 0.1 6.3 7.0 0.0 4.5 4 0 0 4 4 3 0 AAA domain NACHT PF05729.12 RLN55292.1 - 0.00031 20.7 0.2 0.86 9.5 0.0 3.4 3 0 0 3 3 3 1 NACHT domain T2SSE PF00437.20 RLN55292.1 - 0.00041 19.5 0.8 0.042 12.9 0.0 3.3 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_33 PF13671.6 RLN55292.1 - 0.0032 17.7 0.7 0.44 10.7 0.0 4.1 4 0 0 4 4 3 1 AAA domain Roc PF08477.13 RLN55292.1 - 0.0058 16.9 0.5 0.1 12.8 0.0 3.5 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 RLN55292.1 - 0.0079 15.9 0.0 2.4 7.8 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 RLN55292.1 - 0.014 15.4 0.0 0.18 11.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain BCDHK_Adom3 PF10436.9 RLN55292.1 - 0.017 15.0 0.3 0.096 12.5 0.1 2.5 2 0 0 2 2 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase TsaE PF02367.17 RLN55292.1 - 0.022 14.8 0.1 10 6.1 0.0 3.8 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 RLN55292.1 - 0.04 14.0 0.0 37 4.4 0.0 4.4 4 0 0 4 4 3 0 AAA domain (Cdc48 subfamily) ABC_tran PF00005.27 RLN55292.1 - 0.058 13.9 6.1 0.14 12.7 0.0 4.0 4 0 0 4 4 2 0 ABC transporter DUF815 PF05673.13 RLN55292.1 - 0.059 12.5 0.0 7.5 5.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SRP54 PF00448.22 RLN55292.1 - 0.072 12.7 3.3 7 6.2 0.1 4.0 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain Sigma54_activat PF00158.26 RLN55292.1 - 0.078 12.7 0.0 13 5.4 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain PduV-EutP PF10662.9 RLN55292.1 - 0.094 12.5 0.7 16 5.2 0.0 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 RLN55292.1 - 0.11 12.4 0.0 1.9 8.4 0.0 3.1 3 0 0 3 3 2 0 RsgA GTPase FPN1 PF06963.12 RLN55292.1 - 0.16 10.5 0.8 0.42 9.1 0.8 1.6 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DivIVA PF05103.13 RLN55292.1 - 1.1 9.4 25.0 3.8 7.6 3.7 5.4 4 0 0 4 4 4 0 DivIVA protein Fmp27_WPPW PF10359.9 RLN55292.1 - 1.5 7.6 14.6 1.2 7.9 6.2 2.6 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Uteroglobin PF01099.17 RLN55292.1 - 5.2 7.5 5.8 2.1 8.7 0.4 3.3 3 0 0 3 3 1 0 Uteroglobin family OTCace_N PF02729.21 RLN55293.1 - 6.4e-27 94.4 0.0 1.1e-26 93.6 0.0 1.4 1 1 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 RLN55293.1 - 0.0011 19.0 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Glyco_hydro_1 PF00232.18 RLN55298.1 - 1.1e-142 475.7 1.2 1.2e-142 475.5 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 ADH_zinc_N_2 PF13602.6 RLN55299.1 - 8.7e-12 46.2 0.0 7.2e-11 43.3 0.0 2.4 3 1 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 RLN55299.1 - 1e-11 44.9 0.8 1.9e-11 44.1 0.0 1.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN55299.1 - 7e-09 35.5 0.0 2.3e-08 33.9 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_16 PF10294.9 RLN55299.1 - 0.0031 17.3 0.1 0.0056 16.4 0.1 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Eno-Rase_NADH_b PF12242.8 RLN55299.1 - 0.012 15.3 0.3 0.024 14.4 0.3 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PNK3P PF08645.11 RLN55309.1 - 1.6e-54 184.0 0.0 2.5e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 RLN55309.1 - 2.9e-12 47.0 0.2 1.4e-09 38.2 0.2 3.0 1 1 0 1 1 1 1 AAA domain BRCT_2 PF16589.5 RLN55309.1 - 5.3e-05 23.6 0.0 0.00019 21.8 0.0 2.0 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RNA_helicase PF00910.22 RLN55309.1 - 0.022 15.1 0.0 0.049 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase KIP1 PF07765.12 RLN55309.1 - 0.033 14.3 0.0 5 7.3 0.0 2.6 2 0 0 2 2 2 0 KIP1-like protein AAA_25 PF13481.6 RLN55309.1 - 0.081 12.5 0.0 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 RLN55309.1 - 0.11 11.9 0.1 0.26 10.7 0.1 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 RLN55309.1 - 0.12 11.6 0.0 0.4 9.9 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin 6PF2K PF01591.18 RLN55309.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_22 PF13401.6 RLN55309.1 - 0.18 12.1 0.0 0.56 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain PPV_E1_C PF00519.17 RLN55309.1 - 0.19 10.6 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase RRM_1 PF00076.22 RLN55316.1 - 5.2e-07 29.4 0.1 3e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.11 RLN55316.1 - 3.2e-06 26.3 0.0 3.2e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 Apoptosis inhibitory protein 5 (API5) baeRF_family11 PF18855.1 RLN55316.1 - 0.019 15.3 0.2 0.063 13.6 0.2 1.9 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 11 zf-Nse PF11789.8 RLN55317.1 - 0.00079 19.2 0.1 0.0016 18.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 RLN55317.1 - 0.046 14.1 0.9 0.12 12.7 0.9 1.8 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 RLN55317.1 - 0.18 11.6 5.9 0.06 13.2 1.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF5401 PF17380.2 RLN55317.1 - 4.3 5.3 8.1 7.2 4.6 8.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) GPCR_chapero_1 PF11904.8 RLN55319.1 - 0.012 15.1 1.9 0.012 15.1 1.9 2.3 3 0 0 3 3 3 0 GPCR-chaperone PEP-utilisers_N PF05524.13 RLN55319.1 - 0.026 14.7 1.0 0.026 14.7 1.0 3.3 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal TFIIF_alpha PF05793.12 RLN55319.1 - 0.16 10.5 21.4 0.25 9.9 7.6 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Presenilin PF01080.17 RLN55319.1 - 0.7 8.6 19.0 1.1 7.9 4.8 2.2 2 0 0 2 2 2 0 Presenilin FAM60A PF15396.6 RLN55319.1 - 1.3 9.0 9.1 0.81 9.7 1.1 2.4 2 0 0 2 2 2 0 Protein Family FAM60A PTPRCAP PF15713.5 RLN55319.1 - 5.6 7.2 32.1 0.44 10.8 9.1 3.0 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated DUF4746 PF15928.5 RLN55319.1 - 8.4 5.7 18.0 2.8 7.3 2.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) PT PF04886.12 RLN55321.1 - 6e-16 57.7 82.1 1.8e+04 -28.4 82.1 3.7 1 1 0 1 1 1 0 PT repeat Nop14 PF04147.12 RLN55322.1 - 3 6.0 15.0 4.2 5.5 15.0 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 RLN55322.1 - 4 6.9 11.5 7 6.2 11.5 1.3 1 0 0 1 1 1 0 PPP4R2 FYVE PF01363.21 RLN55323.1 - 6.5e-16 58.2 13.3 1.5e-15 57.1 13.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN55323.1 - 0.00072 19.8 3.8 0.0017 18.5 3.8 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger p450 PF00067.22 RLN55333.1 - 5e-12 45.3 0.0 5.3e-12 45.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.7 RLN55335.1 - 1.4e-28 99.3 16.2 5.1e-10 39.8 0.2 6.3 5 1 1 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 RLN55335.1 - 2.3e-24 84.7 27.7 6.4e-10 39.0 0.1 10.0 10 1 0 10 10 10 4 Ankyrin repeat Ank_4 PF13637.6 RLN55335.1 - 1.3e-23 83.0 9.2 5.5e-08 33.2 0.1 8.4 6 3 4 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN55335.1 - 1e-16 59.3 19.4 8.3e-07 28.9 0.1 10.9 12 0 0 12 12 12 2 Ankyrin repeat Ank_5 PF13857.6 RLN55335.1 - 9.4e-14 51.3 13.4 1.4e-07 31.6 0.2 7.7 7 1 0 7 7 7 3 Ankyrin repeats (many copies) LRR_4 PF12799.7 RLN55336.1 - 0.03 14.7 0.1 11 6.6 0.1 4.2 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Tmemb_161AB PF10268.9 RLN55337.1 - 9.9e-41 139.9 4.6 2e-39 135.6 4.6 2.4 1 1 0 1 1 1 1 Predicted transmembrane protein 161AB AIRC PF00731.20 RLN55338.1 - 5.3e-64 214.3 0.8 5.3e-64 214.3 0.8 2.1 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 RLN55338.1 - 2.2e-38 131.5 0.0 3.5e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 RLN55338.1 - 5.4e-19 67.6 0.0 1.2e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 RLN55338.1 - 0.00015 21.3 0.0 0.00038 20.0 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus TTL PF03133.15 RLN55349.1 - 2.5e-74 250.0 0.0 1.5e-57 195.0 0.0 2.2 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RLN55349.1 - 2.2e-06 27.1 0.1 0.00037 19.8 0.0 3.1 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RLN55349.1 - 0.00042 19.7 0.0 0.023 14.0 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp DUF5473 PF17567.2 RLN55350.1 - 0.056 13.7 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5473) TIM PF00121.18 RLN55351.1 - 3.7e-44 150.9 0.1 4.1e-44 150.8 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase IPPT PF01715.17 RLN55351.1 - 0.071 12.9 0.0 0.078 12.8 0.0 1.1 1 0 0 1 1 1 0 IPP transferase Rop-like PF05082.13 RLN55362.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Rop-like CAP_N PF01213.19 RLN55370.1 - 1.8e-20 73.7 0.8 3.1e-20 72.9 0.8 1.6 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_N PF01213.19 RLN55371.1 - 7.2e-13 48.7 0.0 7.8e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 RLN55372.1 - 9.1e-45 152.1 2.2 1.5e-44 151.4 2.2 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal ABC_tran PF00005.27 RLN55372.1 - 8.3e-17 62.0 0.0 1.5e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter TBCC PF07986.12 RLN55372.1 - 0.00018 21.2 1.7 0.00082 19.1 1.7 2.1 1 1 0 1 1 1 1 Tubulin binding cofactor C AAA_29 PF13555.6 RLN55372.1 - 0.0015 18.2 0.2 0.0035 17.1 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN55372.1 - 0.0044 17.0 0.0 0.0081 16.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 RLN55372.1 - 0.0082 16.5 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.20 RLN55372.1 - 0.016 14.4 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit DUF815 PF05673.13 RLN55372.1 - 0.037 13.2 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 RLN55372.1 - 0.055 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_lig_T4_1 PF09511.10 RLN55372.1 - 0.055 13.3 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA ligase DUF87 PF01935.17 RLN55372.1 - 0.098 12.7 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain ABC2_membrane PF01061.24 RLN55373.1 - 2.3e-36 125.2 26.4 2.3e-36 125.2 26.4 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RLN55373.1 - 4.6e-17 62.8 0.0 8.8e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 RLN55373.1 - 0.0029 17.3 0.2 0.0073 16.0 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN55373.1 - 0.0092 15.9 0.1 0.017 15.0 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase G-alpha PF00503.20 RLN55373.1 - 0.033 13.3 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.6 RLN55373.1 - 0.035 14.5 2.1 0.039 14.3 0.3 2.1 2 1 0 2 2 2 0 AAA ATPase domain DUF815 PF05673.13 RLN55373.1 - 0.068 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 RLN55373.1 - 0.088 13.1 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 RLN55373.1 - 0.16 12.0 0.1 0.39 10.8 0.1 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain ABC2_membrane_3 PF12698.7 RLN55373.1 - 0.19 10.8 21.8 0.98 8.5 21.8 2.0 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane PF01061.24 RLN55374.1 - 8.3e-26 90.7 30.4 1.3e-25 90.1 30.4 1.3 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN55374.1 - 0.00099 19.0 0.0 0.00099 19.0 0.0 3.0 3 0 0 3 3 3 1 CDR ABC transporter Cellulase PF00150.18 RLN55410.1 - 5.2e-05 22.8 0.1 7.5e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Sec34 PF04136.15 RLN55411.1 - 7.7e-15 55.1 0.0 4.1e-06 26.8 0.0 3.9 3 0 0 3 3 3 2 Sec34-like family HsbA PF12296.8 RLN55411.1 - 6.1 7.3 12.2 11 6.5 0.7 4.5 2 2 3 5 5 5 0 Hydrophobic surface binding protein A WD40 PF00400.32 RLN55439.1 - 1.5e-06 28.8 0.1 0.0014 19.4 0.0 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN55439.1 - 0.0015 18.8 0.0 5.7 7.3 0.0 3.1 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RLN55439.1 - 0.038 13.8 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A FG-GAP PF01839.23 RLN55439.1 - 0.095 12.9 0.1 0.49 10.6 0.0 2.3 3 0 0 3 3 3 0 FG-GAP repeat Astacin PF01400.24 RLN55440.1 - 1.4e-23 83.5 0.0 2.4e-22 79.5 0.0 2.1 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 RLN55440.1 - 0.024 15.1 1.4 0.035 14.6 0.2 1.9 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 RLN55440.1 - 0.08 12.8 0.3 0.18 11.6 0.3 1.6 1 0 0 1 1 1 0 Matrixin RCC1 PF00415.18 RLN55441.1 - 1.1e-39 134.8 22.8 5.5e-10 39.7 0.1 7.7 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN55441.1 - 3.1e-26 90.6 27.4 4.4e-10 39.1 0.1 6.4 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat TIG PF01833.24 RLN55441.1 - 2.1e-05 24.5 0.1 1 9.5 0.0 5.0 4 1 0 4 4 4 2 IPT/TIG domain Pec_lyase_C PF00544.19 RLN55442.1 - 3.1e-28 98.8 22.7 5.9e-15 55.4 7.6 4.0 2 2 0 2 2 2 2 Pectate lyase Beta_helix PF13229.6 RLN55442.1 - 5.7e-09 36.0 21.9 0.00055 19.8 5.6 3.9 2 2 1 3 3 3 3 Right handed beta helix region Trypsin_2 PF13365.6 RLN55459.1 - 2.5e-16 60.9 0.1 4.4e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 RLN55459.1 - 2.9e-06 27.3 1.1 8.2e-06 25.8 1.1 1.7 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 RLN55460.1 - 1.1e-09 39.3 0.1 1.4e-09 39.0 0.1 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_C3 PF00548.20 RLN55460.1 - 0.045 13.7 0.0 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 3C cysteine protease (picornain 3C) adh_short PF00106.25 RLN55468.1 - 4.5e-28 98.0 0.4 6.2e-28 97.6 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN55468.1 - 5.5e-20 71.9 0.5 7.7e-20 71.4 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN55468.1 - 5.7e-10 39.4 0.2 8.4e-10 38.8 0.2 1.2 1 0 0 1 1 1 1 KR domain Pyr_redox_3 PF13738.6 RLN55468.1 - 5.4e-05 22.6 0.1 7.4e-05 22.2 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 RLN55468.1 - 0.0013 19.0 0.1 0.0026 18.0 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 RLN55468.1 - 0.0022 17.5 0.7 0.003 17.1 0.7 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 RLN55468.1 - 0.019 14.8 0.2 0.031 14.2 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 RLN55468.1 - 0.046 13.1 0.5 0.059 12.8 0.5 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF4917 PF16263.5 RLN55468.1 - 0.099 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4917) ASH PF15780.5 RLN55483.1 - 9.7e-11 41.7 9.7 0.0032 17.6 0.1 7.9 9 0 0 9 9 9 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 RLN55483.1 - 0.0077 16.2 3.5 5.9 7.0 0.6 6.1 7 1 0 7 7 7 1 Protein of unknown function (DUF1573) SusE PF14292.6 RLN55483.1 - 0.073 13.3 0.3 0.43 10.8 0.1 2.5 2 0 0 2 2 2 0 SusE outer membrane protein DUF1640 PF07798.11 RLN55483.1 - 0.13 12.3 1.1 0.27 11.2 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Motile_Sperm PF00635.26 RLN55483.1 - 0.21 11.4 6.8 9.6 6.1 0.0 5.5 7 0 0 7 7 7 0 MSP (Major sperm protein) domain DUF1604 PF07713.13 RLN55516.1 - 1.1e-32 111.7 0.5 1.1e-32 111.7 0.5 4.2 5 0 0 5 5 5 1 Protein of unknown function (DUF1604) G-patch PF01585.23 RLN55516.1 - 1.7e-08 34.2 0.2 1e-07 31.7 0.1 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 RLN55516.1 - 0.013 15.5 0.3 0.013 15.5 0.3 3.0 2 1 0 2 2 2 0 G-patch domain Trypan_PARP PF05887.11 RLN55516.1 - 2.8 7.9 17.6 0.06 13.3 9.6 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) RRM_1 PF00076.22 RLN55517.1 - 4.3e-36 122.6 0.0 4.8e-18 64.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN55517.1 - 6.7e-07 29.3 0.0 0.034 14.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif DTHCT PF08070.11 RLN55517.1 - 9.2e-05 23.1 88.4 0.053 14.3 23.0 4.2 1 1 3 4 4 4 4 DTHCT (NUC029) region Nup35_RRM_2 PF14605.6 RLN55517.1 - 0.062 13.3 0.0 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif HC2 PF07382.11 RLN55517.1 - 0.76 9.8 61.2 3.7 7.6 61.2 2.0 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 FlgD PF03963.14 RLN55519.1 - 0.59 10.5 4.0 17 5.8 0.0 4.3 4 0 0 4 4 4 0 Flagellar hook capping protein - N-terminal region zf-CHY PF05495.12 RLN55520.1 - 7.7e-15 55.2 17.6 7.7e-15 55.2 17.6 5.2 3 2 0 3 3 3 1 CHY zinc finger zinc_ribbon_6 PF14599.6 RLN55520.1 - 1.6e-14 53.6 0.8 1.6e-14 53.6 0.8 5.2 4 3 2 6 6 6 1 Zinc-ribbon zf-RING_2 PF13639.6 RLN55520.1 - 0.00058 20.1 11.6 0.00058 20.1 11.6 6.8 4 1 3 7 7 7 1 Ring finger domain zf-RING_11 PF17123.5 RLN55520.1 - 0.027 14.2 13.2 0.071 12.9 7.2 3.9 2 0 0 2 2 2 0 RING-like zinc finger WW PF00397.26 RLN55522.1 - 3.2e-14 52.7 7.3 1.7e-06 28.0 1.6 2.6 2 0 0 2 2 2 2 WW domain Motile_Sperm PF00635.26 RLN55523.1 - 2.1e-19 69.4 0.0 5.1e-09 36.0 0.0 2.5 2 0 0 2 2 2 2 MSP (Major sperm protein) domain Pex19 PF04614.12 RLN55524.1 - 2.6e-29 102.7 12.7 1.2e-17 64.6 7.0 2.3 2 0 0 2 2 2 2 Pex19 protein family TM231 PF10149.9 RLN55524.1 - 0.0014 18.0 0.4 0.21 10.9 0.0 2.3 1 1 1 2 2 2 2 Transmembrane protein 231 DUF4771 PF15995.5 RLN55524.1 - 0.0032 17.8 2.0 0.026 14.8 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4771) SesA PF17107.5 RLN55524.1 - 0.055 13.7 1.0 0.54 10.5 0.7 2.5 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases VPS13_mid_rpt PF16910.5 RLN55524.1 - 0.067 12.6 0.0 0.21 11.0 0.0 1.8 1 0 0 1 1 1 0 Repeating coiled region of VPS13 SRP54_N PF02881.19 RLN55524.1 - 0.13 12.5 0.8 1.4 9.2 0.0 3.0 2 1 1 3 3 3 0 SRP54-type protein, helical bundle domain Tape_meas_lam_C PF09718.10 RLN55524.1 - 0.15 12.2 2.8 0.43 10.7 2.8 1.8 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Occludin_ELL PF07303.13 RLN55524.1 - 0.42 11.3 2.4 9.9 7.0 0.0 2.9 2 1 1 3 3 3 0 Occludin homology domain ZYG-11_interact PF05884.12 RLN55524.1 - 0.81 9.0 4.3 4.8 6.5 3.3 2.3 1 1 0 1 1 1 0 Interactor of ZYG-11 DnaI_N PF07319.11 RLN55524.1 - 7.4 7.3 7.5 1e+02 3.7 0.1 3.6 3 1 1 4 4 4 0 Primosomal protein DnaI N-terminus PAP2_C PF14360.6 RLN55525.1 - 4.1e-22 78.5 6.5 4.1e-22 78.5 6.5 1.9 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2 PF01569.21 RLN55525.1 - 1.6e-05 24.7 0.1 1.6e-05 24.7 0.1 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 RLN55525.1 - 0.00013 21.7 9.0 0.00036 20.3 9.0 1.8 1 1 0 1 1 1 1 PAP2 superfamily BCDHK_Adom3 PF10436.9 RLN55526.1 - 7.7e-26 90.9 0.0 1.2e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Ank_2 PF12796.7 RLN55526.1 - 3.4e-12 46.8 0.0 7.7e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN55526.1 - 7e-12 45.6 0.2 7.3e-07 29.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN55526.1 - 1.6e-10 40.3 1.4 0.026 15.0 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 RLN55526.1 - 5.8e-09 36.0 1.4 0.17 12.4 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 RLN55526.1 - 4.4e-08 33.3 0.2 0.00011 22.4 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) HATPase_c PF02518.26 RLN55526.1 - 0.00013 22.4 0.0 0.00027 21.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-RING_2 PF13639.6 RLN55527.1 - 3.3e-06 27.3 1.3 3.3e-06 27.3 1.3 2.7 3 0 0 3 3 3 1 Ring finger domain PX PF00787.24 RLN55527.1 - 1.3e-05 25.1 0.6 2.6e-05 24.2 0.3 1.6 1 1 0 1 1 1 1 PX domain zf-RING_11 PF17123.5 RLN55527.1 - 2.4e-05 24.0 1.8 0.0018 17.9 0.4 2.7 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RLN55527.1 - 3.2e-05 23.7 3.0 3.2e-05 23.7 3.0 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN55527.1 - 3.7e-05 23.9 6.0 0.00038 20.7 6.0 2.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RLN55527.1 - 0.00013 21.8 4.1 0.0015 18.4 4.1 2.3 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RLN55527.1 - 0.001 19.0 3.0 0.0017 18.3 0.6 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RLN55527.1 - 0.0067 16.3 6.9 0.03 14.2 7.0 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 RLN55527.1 - 0.14 12.0 2.1 1.6 8.6 0.9 2.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 RLN55527.1 - 0.17 12.0 0.3 0.17 12.0 0.3 2.9 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 11 RING-H2 finger HSF_DNA-bind PF00447.17 RLN55528.1 - 5.4e-06 26.9 0.1 1.5e-05 25.5 0.0 1.7 2 1 0 2 2 2 1 HSF-type DNA-binding START PF01852.19 RLN55529.1 - 2.8e-21 75.9 0.0 3.5e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 START domain GST_C_2 PF13410.6 RLN55530.1 - 2.7e-07 30.5 0.0 6e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RLN55530.1 - 1.2e-06 28.8 0.1 1.6e-05 25.2 0.0 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN55530.1 - 0.0016 18.7 0.1 0.0092 16.3 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RLN55530.1 - 0.0084 16.3 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RLN55530.1 - 0.014 15.6 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RLN55530.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain BRCT PF00533.26 RLN55531.1 - 3.3e-10 40.2 0.0 7.4e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 RLN55531.1 - 4.5e-08 33.4 0.0 1.3e-07 32.0 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 RLN55531.1 - 7.8e-06 25.7 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 RLN55531.1 - 0.00063 19.6 0.1 0.0042 17.0 0.1 2.2 1 1 0 1 1 1 1 twin BRCT domain TPR_2 PF07719.17 RLN55532.1 - 0.0042 17.1 0.0 0.0095 16.0 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN55532.1 - 0.0089 15.8 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN55532.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3160 PF11369.8 RLN55533.1 - 4.7e-113 378.8 0.0 1.5e-112 377.1 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3160) Spidroin_MaSp PF11260.8 RLN55533.1 - 0.16 12.3 1.4 0.47 10.8 1.4 1.8 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 Nup54 PF13874.6 RLN55551.1 - 7.7e-29 100.6 0.2 1.3e-28 99.8 0.2 1.3 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 GrpE PF01025.19 RLN55551.1 - 0.073 12.7 0.3 0.1 12.3 0.3 1.1 1 0 0 1 1 1 0 GrpE Nucleoporin_FG2 PF15967.5 RLN55551.1 - 0.1 11.1 92.0 0.056 12.0 20.7 3.1 1 1 3 4 4 4 0 Nucleoporin FG repeated region Nucleoporin_FG PF13634.6 RLN55551.1 - 2.5 9.0 80.5 27 5.7 25.3 3.8 1 1 3 4 4 4 0 Nucleoporin FG repeat region zf-Paramyx-P PF13008.7 RLN55554.1 - 0.1 12.1 1.1 0.22 11.0 1.1 1.5 1 0 0 1 1 1 0 Zinc-binding domain of Paramyxoviridae V protein cNMP_binding PF00027.29 RLN55555.1 - 8e-08 32.3 0.0 0.0091 16.0 0.0 2.8 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain ADP_ribosyl_GH PF03747.14 RLN55562.1 - 1.5e-18 67.6 0.0 3.2e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DEP PF00610.21 RLN55562.1 - 4.2e-17 62.0 0.4 7.9e-17 61.1 0.4 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GCP_N_terminal PF17681.1 RLN55563.1 - 5e-75 253.0 0.0 7.8e-75 252.3 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal FG-GAP_2 PF14312.6 RLN55563.1 - 1.5e-70 233.3 65.9 1e-10 41.7 0.1 16.8 17 0 0 17 17 17 14 FG-GAP repeat GCP_C_terminal PF04130.13 RLN55563.1 - 2.5e-66 224.3 8.8 4.1e-66 223.6 8.8 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal DEP PF00610.21 RLN55563.1 - 1.1e-12 47.8 0.1 2.5e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Calx-beta PF03160.14 RLN55563.1 - 2.1e-12 47.1 0.7 3.3e-06 27.2 0.0 6.0 5 1 0 5 5 5 2 Calx-beta domain Pkinase PF00069.25 RLN55564.1 - 1.4e-39 136.1 0.0 1.4e-36 126.2 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN55564.1 - 3.3e-22 79.0 0.0 4.3e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN55564.1 - 2.9e-06 26.3 0.0 3.8e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN55564.1 - 5.9e-05 22.5 0.0 8.2e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN55564.1 - 0.0011 19.0 0.1 0.002 18.1 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 RLN55564.1 - 0.0033 17.1 0.0 0.0049 16.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 RLN55564.1 - 0.025 14.0 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bacteriocin_IIi PF11758.8 RLN55564.1 - 0.15 11.9 0.1 0.31 10.9 0.1 1.4 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin DUF2497 PF10691.9 RLN55565.1 - 0.054 13.9 0.1 0.13 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2497) DUF3648 PF12364.8 RLN55565.1 - 0.28 11.4 0.1 0.28 11.4 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3648) NUC153 PF08159.12 RLN55566.1 - 1.3e-07 31.3 0.7 4.6e-07 29.5 0.1 2.2 2 0 0 2 2 2 1 NUC153 domain SLATT_6 PF18169.1 RLN55566.1 - 9.5 5.8 5.6 1.6 8.3 1.6 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 GMC_oxred_C PF05199.13 RLN55575.1 - 5.4e-24 85.4 0.0 6.7e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Calreticulin PF00262.18 RLN55576.1 - 2.9e-146 487.0 4.8 3.8e-146 486.7 4.8 1.1 1 0 0 1 1 1 1 Calreticulin family DUF1416 PF07210.12 RLN55576.1 - 0.057 13.3 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) DUF883 PF05957.13 RLN55576.1 - 0.068 13.8 0.0 0.068 13.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) FAM176 PF14851.6 RLN55576.1 - 0.21 11.3 3.3 0.46 10.1 0.1 2.9 2 1 1 3 3 3 0 FAM176 family GMC_oxred_N PF00732.19 RLN55577.1 - 3.3e-100 335.3 0.0 4.9e-100 334.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 RLN55577.1 - 1.1e-36 126.6 0.0 1.8e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 RLN55577.1 - 7.5e-07 28.6 0.6 0.03 13.4 0.0 2.6 3 0 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.12 RLN55577.1 - 2e-05 23.8 0.0 3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 RLN55577.1 - 2.1e-05 24.3 0.5 0.00021 21.0 0.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RLN55577.1 - 0.00015 21.1 0.1 0.0013 18.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RLN55577.1 - 0.00038 20.6 0.0 0.0015 18.7 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 RLN55577.1 - 0.0021 17.4 0.1 0.18 11.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RLN55577.1 - 0.0031 16.9 0.4 0.52 9.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 RLN55577.1 - 0.0052 16.1 0.1 0.013 14.7 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 RLN55577.1 - 0.021 15.4 0.1 0.78 10.3 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RLN55577.1 - 0.03 13.0 0.1 0.12 11.1 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.16 RLN55577.1 - 0.085 12.5 0.1 0.54 9.9 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 RLN55577.1 - 0.18 12.0 0.0 0.58 10.4 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain zf-CCHC_3 PF13917.6 RLN55578.1 - 2.8e-19 68.8 3.1 6e-19 67.7 3.1 1.6 1 0 0 1 1 1 1 Zinc knuckle Cwf_Cwc_15 PF04889.12 RLN55578.1 - 0.026 14.3 16.8 0.037 13.7 16.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Macoilin PF09726.9 RLN55578.1 - 0.26 9.8 25.9 0.27 9.8 25.9 1.1 1 0 0 1 1 1 0 Macoilin family zf-CCHC PF00098.23 RLN55578.1 - 0.43 10.8 1.9 0.84 9.8 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle FSA_C PF10479.9 RLN55578.1 - 9.7 4.2 14.7 12 3.9 14.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Proteasome PF00227.26 RLN55579.1 - 1.1e-30 106.6 0.0 1.2e-30 106.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit MatE PF01554.18 RLN55581.1 - 4.6e-18 65.4 14.6 1.6e-15 57.2 6.5 2.7 2 1 0 2 2 2 2 MatE EMP24_GP25L PF01105.24 RLN55582.1 - 9.6e-14 51.7 0.0 1.3e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD tRNA-synt_1b PF00579.25 RLN55582.1 - 1.1e-07 31.5 0.1 2.4e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) tRNA-synt_1b PF00579.25 RLN55583.1 - 1.4e-44 152.6 0.1 2.9e-33 115.4 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (W and Y) S4 PF01479.25 RLN55583.1 - 7.9e-05 22.3 0.1 0.00091 18.9 0.0 2.5 2 0 0 2 2 2 1 S4 domain HTH_49 PF18010.1 RLN55583.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Cry35Ab1 HTH C-terminal domain PAP2_C PF14360.6 RLN55584.1 - 8.9e-08 32.6 5.1 8.9e-08 32.6 5.1 3.2 3 0 0 3 3 3 1 PAP2 superfamily C-terminal Acetyltransf_3 PF13302.7 RLN55585.1 - 2e-08 35.0 0.0 2.8e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RLN55585.1 - 0.0011 19.2 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF3265 PF11665.8 RLN55585.1 - 0.016 15.4 0.1 0.046 13.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3265) p53-inducible11 PF14936.6 RLN55586.1 - 0.0018 18.4 0.7 0.0022 18.1 0.7 1.1 1 0 0 1 1 1 1 Tumour protein p53-inducible protein 11 DUF4345 PF14248.6 RLN55586.1 - 0.0034 17.3 4.3 0.0047 16.8 3.7 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4345) DUF1282 PF06930.12 RLN55586.1 - 0.044 13.6 1.2 0.057 13.2 1.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) TatC PF00902.18 RLN55586.1 - 0.44 10.3 3.4 1.9 8.3 3.4 2.0 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) EamA PF00892.20 RLN55586.1 - 0.74 10.0 5.7 0.58 10.3 2.9 1.9 1 1 1 2 2 2 0 EamA-like transporter family WD40 PF00400.32 RLN55587.1 - 1.4e-21 76.3 11.2 2.9e-08 34.2 0.3 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN55587.1 - 2.4e-11 43.8 0.0 7.2e-05 23.0 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 RLN55587.1 - 0.64 10.0 5.2 5.7 7.0 0.1 3.6 3 1 1 4 4 4 0 WD40-like Beta Propeller Repeat DDE_Tnp_ISL3 PF01610.17 RLN55589.1 - 1.4 8.6 7.4 3 7.5 7.4 1.5 1 0 0 1 1 1 0 Transposase DUF2852 PF11014.8 RLN55628.1 - 0.98 9.6 0.0 0.98 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) DUF5083 PF16890.5 RLN55629.1 - 0.059 13.1 0.9 0.14 11.9 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) Zeta_toxin PF06414.12 RLN55638.1 - 8.8e-14 51.2 0.0 1.7e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.6 RLN55638.1 - 9.4e-07 29.1 0.0 2.1e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RLN55638.1 - 0.0001 22.8 0.1 0.0015 19.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 RLN55638.1 - 0.00043 20.3 0.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 2 P-loop Nucleotide Kinase3 AAA_17 PF13207.6 RLN55638.1 - 0.0057 17.1 0.1 1.2 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN55638.1 - 0.012 16.0 0.8 0.079 13.3 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 RLN55638.1 - 0.11 12.3 1.1 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 RLN55638.1 - 0.12 12.1 0.0 0.37 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Ecm29 PF13001.7 RLN55639.1 - 4.6e-29 101.5 1.6 4.6e-29 101.5 1.6 3.1 3 0 0 3 3 3 2 Proteasome stabiliser HEAT PF02985.22 RLN55639.1 - 1.8 9.0 16.0 0.66 10.4 0.2 6.6 8 0 0 8 8 8 0 HEAT repeat Ribosomal_S6 PF01250.17 RLN55640.1 - 6.7e-13 48.7 0.0 1.3e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6 DSS1_SEM1 PF05160.13 RLN55641.1 - 2.4e-16 59.5 15.8 3e-16 59.2 15.8 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family AAA PF00004.29 RLN55642.1 - 3e-53 179.8 0.0 9.1e-43 145.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN55642.1 - 8.3e-12 45.8 0.4 0.00012 22.5 0.0 3.9 2 1 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 RLN55642.1 - 2.1e-08 34.2 0.1 0.011 15.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RLN55642.1 - 7.1e-08 32.4 0.0 0.00013 21.8 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 RLN55642.1 - 7.4e-07 29.8 0.0 0.011 16.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 RLN55642.1 - 3.5e-06 26.4 0.1 0.18 10.9 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF815) TsaE PF02367.17 RLN55642.1 - 5.7e-06 26.3 0.0 0.066 13.2 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 RLN55642.1 - 8.5e-06 25.2 0.0 0.011 15.0 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 RLN55642.1 - 1.9e-05 24.9 0.2 0.018 15.3 0.0 3.3 2 2 1 3 3 3 1 AAA domain AAA_33 PF13671.6 RLN55642.1 - 2.5e-05 24.5 0.0 0.32 11.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 RLN55642.1 - 3.9e-05 23.7 0.0 0.2 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 RLN55642.1 - 6.8e-05 23.2 0.0 0.22 11.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_lid_3 PF17862.1 RLN55642.1 - 0.00014 21.6 6.2 0.0056 16.5 1.2 2.7 2 0 0 2 2 2 1 AAA+ lid domain AAA_7 PF12775.7 RLN55642.1 - 0.00025 20.6 0.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 RLN55642.1 - 0.00043 20.6 0.0 0.054 13.9 0.0 2.5 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 RLN55642.1 - 0.00069 19.4 0.0 0.0036 17.1 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 RLN55642.1 - 0.00087 19.0 0.0 0.55 9.9 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 RLN55642.1 - 0.0015 18.4 0.0 0.57 10.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 RLN55642.1 - 0.0018 18.2 0.2 0.86 9.5 0.1 2.3 2 0 0 2 2 2 1 NTPase NACHT PF05729.12 RLN55642.1 - 0.004 17.1 0.1 0.8 9.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 RLN55642.1 - 0.0041 16.5 0.1 0.03 13.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 RLN55642.1 - 0.0065 16.6 0.0 0.55 10.3 0.0 3.0 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) ATPase PF06745.13 RLN55642.1 - 0.0075 15.6 0.0 0.02 14.2 0.0 1.6 2 0 0 2 2 1 1 KaiC AAA_25 PF13481.6 RLN55642.1 - 0.0079 15.8 0.0 0.14 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 RLN55642.1 - 0.0093 15.2 0.0 1.9 7.6 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Parvo_NS1 PF01057.17 RLN55642.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 RLN55642.1 - 0.013 16.0 0.1 1.3 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 RLN55642.1 - 0.015 14.6 0.0 5.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 RLN55642.1 - 0.035 13.8 0.0 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 RLN55642.1 - 0.06 13.3 0.0 8.6 6.2 0.0 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 RLN55642.1 - 0.068 12.9 0.0 17 5.3 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.15 RLN55642.1 - 0.077 12.9 0.0 17 5.3 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain Inhibitor_I36 PF03995.13 RLN55642.1 - 0.085 12.8 0.4 0.45 10.5 0.0 2.3 2 0 0 2 2 2 0 Peptidase inhibitor family I36 T2SSE PF00437.20 RLN55642.1 - 0.11 11.6 0.0 0.69 8.9 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.16 RLN55642.1 - 0.19 11.2 0.0 0.38 10.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 RLN55642.1 - 0.21 10.8 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Inhibitor_I36 PF03995.13 RLN55643.1 - 0.029 14.3 4.1 0.38 10.7 1.6 3.2 2 1 0 2 2 2 0 Peptidase inhibitor family I36 Crystall_3 PF08964.10 RLN55643.1 - 0.18 12.0 0.3 3.2 8.0 0.1 2.7 3 0 0 3 3 3 0 Beta/Gamma crystallin RRM_1 PF00076.22 RLN55644.1 - 0.00094 19.0 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN55644.1 - 0.0096 16.0 0.0 0.017 15.2 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif DUF4381 PF14316.6 RLN55645.1 - 0.0061 16.8 4.0 0.46 10.7 0.3 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4381) DUF802 PF05650.11 RLN55645.1 - 2.6 8.6 9.6 25 5.4 3.6 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF802) Y_phosphatase PF00102.27 RLN55659.1 - 4.1e-55 186.9 0.0 6.6e-55 186.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CTP_transf_1 PF01148.20 RLN55659.1 - 8.9e-36 124.0 20.9 1.8e-35 123.0 11.5 2.5 2 1 0 2 2 2 2 Cytidylyltransferase family DSPc PF00782.20 RLN55659.1 - 5.8e-05 22.9 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF3037 PF11236.8 RLN55660.1 - 0.038 14.4 0.1 2.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) Pkinase PF00069.25 RLN55662.1 - 3.7e-45 154.3 0.0 6.3e-45 153.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN55662.1 - 7.8e-41 140.1 0.0 3.3e-40 138.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase LRR_4 PF12799.7 RLN55662.1 - 2.7e-05 24.4 5.6 0.00032 21.0 0.2 3.3 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) CD34_antigen PF06365.12 RLN55662.1 - 4.5e-05 23.1 0.0 8.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family LRR_8 PF13855.6 RLN55662.1 - 0.00034 20.3 5.6 0.00039 20.1 3.7 2.1 2 0 0 2 2 2 1 Leucine rich repeat SKG6 PF08693.10 RLN55662.1 - 0.028 13.8 1.6 0.079 12.4 1.6 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.6 RLN55662.1 - 0.048 13.6 0.1 0.083 12.8 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF1180 PF06679.12 RLN55662.1 - 0.054 13.9 0.5 0.1 13.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Haspin_kinase PF12330.8 RLN55662.1 - 0.12 11.3 0.0 0.12 11.3 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain Arv1 PF04161.13 RLN55663.1 - 2.7e-48 164.9 0.4 3.8e-48 164.4 0.4 1.2 1 0 0 1 1 1 1 Arv1-like family DUF935 PF06074.12 RLN55663.1 - 0.084 11.6 3.0 0.12 11.1 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF935) TF_Zn_Ribbon PF08271.12 RLN55663.1 - 0.13 11.8 0.5 0.31 10.6 0.5 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Mg_trans_NIPA PF05653.14 RLN55664.1 - 3e-12 46.3 10.1 7.9e-10 38.3 0.6 2.2 2 0 0 2 2 2 2 Magnesium transporter NIPA Frizzled PF01534.17 RLN55664.1 - 0.07 12.2 1.7 2.4 7.1 0.3 2.8 3 0 0 3 3 3 0 Frizzled/Smoothened family membrane region PalH PF08733.10 RLN55664.1 - 0.12 11.3 2.3 0.23 10.4 1.8 1.6 1 1 0 1 1 1 0 PalH/RIM21 E1-E2_ATPase PF00122.20 RLN55664.1 - 2.3 7.7 4.0 0.58 9.6 0.1 2.0 2 1 0 2 2 2 0 E1-E2 ATPase DUF805 PF05656.14 RLN55664.1 - 3.2 8.2 11.2 1.6 9.2 6.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF805) CTP_transf_1 PF01148.20 RLN55665.1 - 5.5e-36 124.7 21.8 9.7e-35 120.6 14.9 2.6 2 1 0 2 2 2 2 Cytidylyltransferase family DUF5489 PF17592.2 RLN55665.1 - 0.19 12.3 0.3 0.19 12.3 0.3 2.8 3 1 0 3 3 3 0 Family of unknown function (DUF5489) Nnf1 PF03980.14 RLN55666.1 - 1.9e-14 54.0 18.2 6.8e-14 52.2 18.2 1.9 1 1 0 1 1 1 1 Nnf1 CRIC_ras_sig PF10534.9 RLN55666.1 - 0.041 14.1 5.7 0.15 12.3 1.1 2.7 2 1 1 3 3 3 0 Connector enhancer of kinase suppressor of ras Sigma70_ner PF04546.13 RLN55666.1 - 0.23 11.3 13.5 0.14 12.0 11.9 1.4 1 1 0 1 1 1 0 Sigma-70, non-essential region Pepsin-I3 PF06394.13 RLN55666.1 - 0.8 9.9 4.3 0.48 10.7 2.0 1.8 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain Fzo_mitofusin PF04799.13 RLN55666.1 - 0.87 9.1 9.8 0.88 9.1 4.6 2.1 2 0 0 2 2 2 0 fzo-like conserved region CRA PF06589.11 RLN55666.1 - 1.2 9.3 2.8 1.5 8.9 1.9 1.6 1 1 1 2 2 2 0 Circumsporozoite-related antigen (CRA) DUF1382 PF07131.11 RLN55666.1 - 1.3 9.1 0.0 1.3 9.1 0.0 3.4 4 1 0 4 4 4 0 Protein of unknown function (DUF1382) zf-CpG_bind_C PF12269.8 RLN55666.1 - 1.7 8.4 10.0 2.2 8.0 4.7 2.1 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain HsdM_N PF12161.8 RLN55666.1 - 5.7 7.6 6.5 8.6 7.0 5.4 1.7 1 1 1 2 2 2 0 HsdM N-terminal domain Mannosyl_trans3 PF11051.8 RLN55667.1 - 2.2e-29 102.7 0.0 2.8e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative CTP_transf_1 PF01148.20 RLN55668.1 - 1.5e-68 231.5 53.9 3.2e-34 118.9 13.6 4.5 4 0 0 4 4 4 4 Cytidylyltransferase family YL1_C PF08265.11 RLN55668.1 - 0.043 13.6 0.2 0.83 9.5 0.0 2.6 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain HA PF03457.14 RLN55669.1 - 1.7e-29 101.9 14.7 7.5e-05 23.0 0.1 9.4 9 1 1 10 10 10 7 Helicase associated domain CCT PF06203.14 RLN55669.1 - 2.3e-17 62.8 11.0 5e-17 61.7 11.0 1.6 1 0 0 1 1 1 1 CCT motif PKS_DE PF18369.1 RLN55669.1 - 0.1 13.2 3.9 15 6.2 0.2 4.8 4 0 0 4 4 4 0 Polyketide synthase dimerisation element domain Mod_r PF07200.13 RLN55691.1 - 0.0096 16.0 1.3 0.0096 16.0 1.3 2.9 2 1 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein CENP-H PF05837.12 RLN55691.1 - 0.015 15.7 0.1 0.015 15.7 0.1 3.5 2 1 1 3 3 3 0 Centromere protein H (CENP-H) DUF641 PF04859.12 RLN55691.1 - 0.026 14.9 0.8 0.026 14.9 0.8 2.4 3 0 0 3 3 1 0 Plant protein of unknown function (DUF641) DUF1465 PF07323.12 RLN55691.1 - 0.026 14.4 7.6 0.47 10.3 1.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1465) Leu_zip PF15294.6 RLN55691.1 - 0.027 14.0 10.0 1 8.8 0.4 2.3 2 0 0 2 2 2 0 Leucine zipper FapA PF03961.13 RLN55691.1 - 0.041 12.5 0.8 0.1 11.2 0.0 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A HMMR_N PF15905.5 RLN55691.1 - 0.06 12.8 12.9 0.64 9.4 0.4 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal FPP PF05911.11 RLN55691.1 - 0.078 11.2 7.5 0.18 10.0 1.8 2.3 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil DivIC PF04977.15 RLN55691.1 - 0.08 12.7 15.2 0.53 10.1 0.1 4.4 3 1 0 4 4 4 0 Septum formation initiator DUF16 PF01519.16 RLN55691.1 - 0.27 11.7 1.7 1.1 9.7 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 TMCO5 PF14992.6 RLN55691.1 - 0.62 9.6 3.5 0.46 10.0 0.0 2.1 2 0 0 2 2 2 0 TMCO5 family TACC_C PF05010.14 RLN55691.1 - 1.1 9.0 10.3 0.28 10.9 1.3 2.6 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal MbeD_MobD PF04899.12 RLN55691.1 - 1.2 9.3 9.8 4.1 7.6 0.2 3.8 4 0 0 4 4 3 0 MbeD/MobD like Fungal_TACC PF12709.7 RLN55691.1 - 1.5 9.3 3.2 25 5.4 0.2 3.0 2 1 1 3 3 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins BST2 PF16716.5 RLN55691.1 - 1.8 9.2 9.2 35 5.1 0.3 4.0 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 ADIP PF11559.8 RLN55691.1 - 2.1 8.4 22.5 0.12 12.5 4.3 3.9 2 2 0 4 4 4 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 RLN55691.1 - 2.3 8.2 13.5 1.7 8.6 0.5 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 RLN55691.1 - 2.7 8.1 9.7 2 8.5 0.3 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ACCA PF03255.14 RLN55691.1 - 3.7 7.4 6.1 25 4.7 0.0 3.8 3 1 1 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF4795 PF16043.5 RLN55691.1 - 3.8 7.1 8.9 0.36 10.4 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) GrpE PF01025.19 RLN55691.1 - 3.8 7.1 7.2 1.4 8.5 0.4 2.4 2 0 0 2 2 2 0 GrpE DUF948 PF06103.11 RLN55691.1 - 4.7 7.6 5.8 3.7 7.9 2.1 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 RLN55691.1 - 6.7 7.3 23.9 0.12 12.9 1.8 3.3 3 1 0 3 3 3 0 Apg6 coiled-coil region Phage_antitermQ PF06530.12 RLN55692.1 - 0.028 14.3 0.0 0.093 12.6 0.0 1.9 1 0 0 1 1 1 0 Phage antitermination protein Q FAD_binding_3 PF01494.19 RLN55716.1 - 0.00011 21.6 0.1 0.00038 19.8 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 RLN55716.1 - 0.00023 20.5 0.1 0.00097 18.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 RLN55716.1 - 0.00059 19.2 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RLN55716.1 - 0.00089 18.1 0.1 0.0015 17.3 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 RLN55716.1 - 0.0011 18.6 0.1 0.002 17.8 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 RLN55716.1 - 0.0018 17.4 0.2 0.0034 16.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 RLN55716.1 - 0.0038 16.6 0.1 0.0071 15.7 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain SPOR PF05036.13 RLN55716.1 - 0.0084 16.5 0.3 0.048 14.1 0.1 2.3 2 0 0 2 2 2 1 Sporulation related domain NAD_binding_8 PF13450.6 RLN55716.1 - 0.0094 16.2 0.0 0.076 13.3 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 RLN55716.1 - 0.029 13.7 0.4 0.051 12.9 0.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 RLN55716.1 - 0.081 13.5 0.2 0.24 12.0 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 RLN55716.1 - 0.13 12.7 0.0 0.44 11.0 0.0 2.0 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 RLN55716.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain LRS4 PF10422.9 RLN55716.1 - 0.43 10.1 2.5 0.8 9.2 2.5 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Pkinase PF00069.25 RLN55717.1 - 1.4e-73 247.6 0.0 2e-73 247.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN55717.1 - 3.8e-33 114.9 0.0 5.9e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN55717.1 - 2.1e-06 26.8 0.1 1.1e-05 24.4 0.0 2.1 2 1 0 2 2 2 1 Fungal protein kinase Shugoshin_C PF07557.11 RLN55717.1 - 2.8e-06 27.0 0.0 6.2e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Shugoshin C terminus Kdo PF06293.14 RLN55717.1 - 0.0011 18.4 0.1 0.0021 17.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN55717.1 - 0.0019 17.5 0.1 0.006 15.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like bZIP_1 PF00170.21 RLN55717.1 - 0.025 14.7 0.6 0.76 9.9 0.2 2.5 2 0 0 2 2 2 0 bZIP transcription factor YrbL-PhoP_reg PF10707.9 RLN55717.1 - 0.035 13.6 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 RLN55717.1 - 0.047 13.6 0.1 0.19 11.7 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 RLN55717.1 - 0.052 12.5 0.1 0.082 11.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase LPP PF04728.13 RLN55718.1 - 0.09 13.2 0.1 0.17 12.3 0.1 1.4 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Ndc1_Nup PF09531.10 RLN55718.1 - 5 5.7 5.1 6.2 5.4 5.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Methyltransf_32 PF13679.6 RLN55719.1 - 5e-10 39.6 1.2 3.4e-08 33.6 1.2 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN55719.1 - 3.4e-07 30.2 0.0 4.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 RLN55719.1 - 1.2e-06 28.2 0.5 0.00095 18.8 0.6 3.0 1 1 1 2 2 2 1 Methyltransferase TRM13 Methyltransf_25 PF13649.6 RLN55719.1 - 3.3e-06 27.7 0.0 8.7e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN55719.1 - 3.7e-05 23.3 0.0 0.00012 21.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain GidB PF02527.15 RLN55719.1 - 8.6e-05 21.9 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_4 PF02390.17 RLN55719.1 - 0.00026 20.5 0.0 0.00048 19.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.12 RLN55719.1 - 0.0063 17.2 0.0 0.014 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 RLN55719.1 - 0.061 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 RLN55719.1 - 0.072 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Met_10 PF02475.16 RLN55719.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.6 2 0 0 2 2 2 0 Met-10+ like-protein zf-TRM13_CCCH PF11722.8 RLN55719.1 - 0.53 10.1 2.8 0.86 9.4 1.1 2.4 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein RMI1_N PF08585.12 RLN55720.1 - 1.4e-23 83.8 0.0 3.1e-17 63.1 0.0 2.4 1 1 1 2 2 2 2 RecQ mediated genome instability protein RMI1_C PF16099.5 RLN55720.1 - 1.7e-19 70.1 0.0 2.8e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold Popeye PF04831.13 RLN55720.1 - 0.097 12.8 1.2 0.24 11.6 1.2 1.6 1 0 0 1 1 1 0 Popeye protein conserved region Glucos_trans_II PF14264.6 RLN55720.1 - 0.29 10.5 4.2 0.56 9.5 4.2 1.4 1 0 0 1 1 1 0 Glucosyl transferase GtrII UPF0715 PF17094.5 RLN55720.1 - 0.63 10.6 7.3 0.15 12.6 0.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0715) Acyl_transf_3 PF01757.22 RLN55720.1 - 1.2 8.1 5.8 1.9 7.5 5.8 1.2 1 0 0 1 1 1 0 Acyltransferase family PhosphMutase PF10143.9 RLN55721.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase S-AdoMet_synt_C PF02773.16 RLN55722.1 - 8.1e-65 217.0 0.4 1.6e-64 216.0 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 RLN55722.1 - 1.7e-47 160.6 0.1 3.8e-47 159.5 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 RLN55722.1 - 2e-43 147.1 0.3 2e-43 147.1 0.3 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain DLH PF01738.18 RLN55725.1 - 2.1e-17 63.4 0.1 2.6e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family HECT PF00632.25 RLN55726.1 - 8.6e-79 265.2 0.2 1.2e-78 264.7 0.2 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) fn3 PF00041.21 RLN55726.1 - 1.7e-17 63.5 0.9 1.2e-07 32.0 0.2 2.7 2 0 0 2 2 2 2 Fibronectin type III domain WW PF00397.26 RLN55726.1 - 0.00064 19.7 2.5 0.0011 19.0 0.4 2.3 2 0 0 2 2 2 1 WW domain Aldedh PF00171.22 RLN55727.1 - 5.9e-129 430.6 0.0 6.8e-129 430.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MAD PF05557.13 RLN55728.1 - 4.1e-21 75.0 26.5 1.1e-19 70.4 1.1 5.0 2 2 1 3 3 3 2 Mitotic checkpoint protein Myosin_tail_1 PF01576.19 RLN55728.1 - 0.00046 18.2 17.2 0.00046 18.2 17.2 2.5 2 1 0 2 2 2 1 Myosin tail Lectin_N PF03954.14 RLN55728.1 - 0.0011 18.7 6.4 0.0011 18.7 6.4 4.9 2 2 3 5 5 5 1 Hepatic lectin, N-terminal domain COMM_domain PF07258.14 RLN55728.1 - 0.79 9.9 10.6 0.21 11.7 1.0 3.4 3 1 0 3 3 3 0 COMM domain V_ATPase_I PF01496.19 RLN55728.1 - 2.2 6.1 37.3 1.5 6.6 4.9 3.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Dynactin_p62 PF05502.13 RLN55729.1 - 1.9e-15 56.6 10.4 1.4e-13 50.4 10.4 2.7 1 1 0 1 1 1 1 Dynactin p62 family NucS PF01939.16 RLN55739.1 - 0.093 12.1 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Endonuclease NucS Tudor_1_RapA PF18339.1 RLN55750.1 - 0.051 13.5 0.2 11 6.1 0.0 2.1 2 0 0 2 2 2 0 RapA N-terminal Tudor like domain 1 W2 PF02020.18 RLN55751.1 - 5.6e-13 48.8 12.7 5.6e-13 48.8 12.7 2.9 2 2 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 RLN55751.1 - 1.6e-05 24.4 14.3 0.34 10.7 1.3 4.2 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 RLN55751.1 - 0.0065 14.7 1.1 0.019 13.1 1.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 RLN55751.1 - 0.014 15.1 12.1 0.4 10.5 0.7 3.6 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase Promethin PF16015.5 RLN55752.1 - 0.046 13.6 0.2 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Promethin ABC_membrane PF00664.23 RLN55760.1 - 1.6e-48 165.7 35.8 1.6e-27 96.9 15.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN55760.1 - 4.8e-28 98.4 1.2 2.7e-17 63.6 0.0 3.4 2 1 1 3 3 3 2 ABC transporter RsgA_GTPase PF03193.16 RLN55760.1 - 5.5e-10 39.4 2.0 1.6e-05 24.9 0.4 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RLN55760.1 - 6.9e-08 32.6 0.8 0.012 15.7 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 RLN55760.1 - 5.9e-06 26.9 1.0 0.014 15.9 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 RLN55760.1 - 6.8e-06 25.7 3.3 0.01 15.5 0.4 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 RLN55760.1 - 8.6e-06 26.0 2.4 0.02 15.0 0.1 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain Dynamin_N PF00350.23 RLN55760.1 - 4.7e-05 23.5 5.1 0.0035 17.4 0.5 2.5 2 0 0 2 2 2 2 Dynamin family AAA_16 PF13191.6 RLN55760.1 - 5.6e-05 23.6 0.2 0.091 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.18 RLN55760.1 - 6.3e-05 22.4 1.7 0.12 11.7 0.3 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AIG1 PF04548.16 RLN55760.1 - 0.00013 21.3 1.7 0.004 16.5 0.1 2.4 2 0 0 2 2 2 1 AIG1 family AAA_21 PF13304.6 RLN55760.1 - 0.00096 19.0 0.0 0.17 11.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RLN55760.1 - 0.001 18.6 5.6 0.013 14.9 0.3 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RLN55760.1 - 0.0013 19.0 1.2 0.92 9.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 RLN55760.1 - 0.0017 17.4 1.4 0.14 11.2 0.5 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF815 PF05673.13 RLN55760.1 - 0.0026 17.0 0.6 0.31 10.2 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 RLN55760.1 - 0.0058 16.8 0.2 0.38 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RLN55760.1 - 0.0072 15.9 1.4 1.8 8.0 0.3 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region cobW PF02492.19 RLN55760.1 - 0.0082 15.8 1.3 0.71 9.4 0.2 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.14 RLN55760.1 - 0.011 15.0 0.0 1.2 8.3 0.0 2.6 2 1 0 2 2 2 0 KAP family P-loop domain Roc PF08477.13 RLN55760.1 - 0.02 15.1 1.2 4.8 7.4 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 RLN55760.1 - 0.021 15.2 0.4 7.8 6.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 RLN55760.1 - 0.024 14.4 0.0 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 RLN55760.1 - 0.025 13.9 1.0 0.41 9.9 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin Septin PF00735.18 RLN55760.1 - 0.036 13.3 0.1 6.9 5.9 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_18 PF13238.6 RLN55760.1 - 0.11 13.0 0.2 21 5.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 RLN55760.1 - 0.12 12.8 0.0 9.4 6.7 0.0 3.1 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) IIGP PF05049.13 RLN55760.1 - 0.13 11.3 1.1 8.4 5.3 0.1 2.4 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.18 RLN55760.1 - 0.13 11.7 0.8 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Gtr1_RagA PF04670.12 RLN55760.1 - 0.21 10.9 0.8 1.2 8.4 0.1 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_15 PF13175.6 RLN55760.1 - 0.22 11.2 2.8 1.5 8.5 0.7 2.1 2 0 0 2 2 2 0 AAA ATPase domain Adeno_IVa2 PF02456.15 RLN55760.1 - 0.24 10.2 1.0 0.97 8.2 0.1 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein NACHT PF05729.12 RLN55760.1 - 0.33 10.8 2.7 3.2 7.7 0.1 2.7 3 0 0 3 3 2 0 NACHT domain ATP_bind_1 PF03029.17 RLN55760.1 - 1.6 8.4 4.7 14 5.4 0.3 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DDE_3 PF13358.6 RLN55761.1 - 1.6e-18 66.8 0.0 3.2e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 RLN55761.1 - 4.4e-06 26.3 0.3 1.3e-05 24.8 0.3 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 RLN55761.1 - 4.9e-06 27.1 0.0 1.2e-05 25.8 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 RLN55761.1 - 8.9e-05 22.5 0.8 8.9e-05 22.5 0.8 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 RLN55761.1 - 0.0015 18.8 0.1 0.0036 17.6 0.1 1.6 1 0 0 1 1 1 1 Transposase HypF_C PF17788.1 RLN55761.1 - 0.011 16.5 0.1 0.04 14.6 0.0 2.0 2 1 0 2 2 2 0 HypF Kae1-like domain BRCA2 PF00634.18 RLN55782.1 - 1.7e-36 123.5 34.6 0.0015 18.2 0.2 10.7 10 0 0 10 10 10 10 BRCA2 repeat BRCA-2_OB1 PF09103.10 RLN55782.1 - 4.7e-27 94.4 0.0 9.2e-27 93.4 0.0 1.5 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 RLN55782.1 - 4.9e-14 52.4 0.0 9.1e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 BRCA2, helical Microtub_bd PF16796.5 RLN55782.1 - 0.00022 21.2 0.4 6.2 6.7 0.0 5.9 7 0 0 7 7 7 1 Microtubule binding GH97_N PF14508.6 RLN55782.1 - 0.048 13.1 0.1 10 5.6 0.0 3.6 3 1 1 4 4 4 0 Glycosyl-hydrolase 97 N-terminal DUF3552 PF12072.8 RLN55782.1 - 0.11 12.0 0.1 0.3 10.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Phage_GP20 PF06810.11 RLN55800.1 - 0.043 13.6 3.9 0.074 12.9 3.9 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 IFT20 PF14931.6 RLN55800.1 - 1.7 8.8 9.9 6 7.1 3.8 2.4 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 DMPK_coil PF08826.10 RLN55800.1 - 6.2 7.0 12.3 8.5 6.6 4.8 2.4 1 1 1 2 2 2 0 DMPK coiled coil domain like M PF02370.16 RLN55800.1 - 8.3 7.3 9.8 5.6 7.9 0.6 3.5 3 0 0 3 3 3 0 M protein repeat Neuropeptide_S PF14993.6 RLN55801.1 - 0.13 12.1 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Neuropeptide S precursor protein BclA_C PF18573.1 RLN55801.1 - 0.16 11.9 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 BclA C-terminal domain Glyco_hydro_3 PF00933.21 RLN55811.1 - 9.7e-52 176.3 0.0 5.2e-51 173.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN55811.1 - 5.5e-40 137.5 0.1 1.7e-39 135.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RLN55811.1 - 4.7e-13 49.1 0.0 1e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.11 RLN55811.1 - 0.047 14.0 0.6 0.13 12.6 0.1 2.0 2 0 0 2 2 2 0 CARDB fn3_5 PF06280.12 RLN55811.1 - 0.34 11.6 2.1 0.36 11.5 0.5 1.8 2 0 0 2 2 2 0 Fn3-like domain Rad51 PF08423.11 RLN55812.1 - 1.5e-90 303.0 1.0 1.5e-78 263.6 0.2 2.1 1 1 1 2 2 2 2 Rad51 AAA_25 PF13481.6 RLN55812.1 - 1.1e-07 31.6 0.0 1.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 RLN55812.1 - 5.8e-07 29.2 0.0 7.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 RLN55812.1 - 0.00046 19.6 0.0 0.00096 18.6 0.0 1.6 1 1 0 1 1 1 1 KaiC AAA_24 PF13479.6 RLN55812.1 - 0.0022 17.7 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 RLN55812.1 - 0.0042 17.7 2.4 0.022 15.4 1.1 2.5 1 1 1 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 RLN55812.1 - 0.021 14.7 0.3 0.3 11.0 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif ABC_membrane PF00664.23 RLN55813.1 - 9.4e-47 159.9 19.3 1.4e-46 159.4 19.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN55813.1 - 1.4e-37 129.3 0.0 1.1e-34 119.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN55813.1 - 6e-07 29.1 5.1 0.057 12.8 0.1 3.5 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 RLN55813.1 - 0.0013 18.0 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 RLN55813.1 - 0.0025 18.1 0.7 0.029 14.6 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 RLN55813.1 - 0.0037 17.0 0.3 0.015 15.0 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN55813.1 - 0.0039 17.6 1.1 0.013 15.9 1.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.6 RLN55813.1 - 0.007 16.6 3.4 2.2 8.6 0.3 3.8 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 RLN55813.1 - 0.011 14.6 0.2 0.03 13.1 0.0 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_21 PF13304.6 RLN55813.1 - 0.014 15.2 0.3 0.65 9.8 0.1 2.4 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 RLN55813.1 - 0.02 14.6 0.0 0.04 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 RLN55813.1 - 0.027 14.2 0.0 0.29 10.9 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase RsgA_GTPase PF03193.16 RLN55813.1 - 0.036 14.0 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 RLN55813.1 - 0.039 13.7 0.4 0.15 11.8 0.3 2.0 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 RLN55813.1 - 0.093 12.8 0.0 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_15 PF13175.6 RLN55813.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 RLN55813.1 - 0.18 10.9 0.0 0.37 9.9 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit SWIM PF04434.17 RLN55814.1 - 0.058 13.1 3.3 0.16 11.6 3.3 1.8 1 0 0 1 1 1 0 SWIM zinc finger Pkinase PF00069.25 RLN55833.1 - 1.2e-72 244.5 0.0 1.4e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN55833.1 - 2.1e-28 99.3 0.0 3e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Bactofilin PF04519.13 RLN55833.1 - 1.2e-18 67.1 3.0 2.3e-18 66.3 3.0 1.5 1 0 0 1 1 1 1 Polymer-forming cytoskeletal Kinase-like PF14531.6 RLN55833.1 - 0.00019 20.9 0.0 0.0093 15.3 0.0 2.2 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 RLN55833.1 - 0.06 13.3 0.3 0.22 11.4 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN55833.1 - 0.17 10.8 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DDE_3 PF13358.6 RLN55834.1 - 9.3e-07 28.7 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease WBS_methylT PF12589.8 RLN55835.1 - 9.3e-10 39.1 13.5 4.4e-08 33.8 9.7 2.7 2 1 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 RLN55835.1 - 1.4e-08 35.2 0.0 2.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN55835.1 - 8.5e-08 32.8 0.0 1.7e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN55835.1 - 0.012 15.4 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 RLN55835.1 - 0.016 15.1 0.0 0.037 13.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DUF3245 PF11595.8 RLN55835.1 - 0.02 15.4 0.8 0.035 14.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Methyltransf_12 PF08242.12 RLN55835.1 - 0.13 13.0 0.0 0.36 11.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Dynein_light PF01221.18 RLN55848.1 - 8.4e-23 80.5 0.9 9.9e-23 80.3 0.9 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Siva PF05458.12 RLN55850.1 - 0.022 14.5 16.0 0.048 13.3 16.0 1.6 1 0 0 1 1 1 0 Cd27 binding protein (Siva) DUF3287 PF11690.8 RLN55851.1 - 0.078 12.7 0.9 0.75 9.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Peptidase_S10 PF00450.22 RLN55852.1 - 2.1e-78 264.6 0.0 2.8e-78 264.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase MM_CoA_mutase PF01642.22 RLN55852.1 - 0.046 12.3 0.0 0.08 11.5 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase WD40 PF00400.32 RLN55853.1 - 3.3e-67 220.8 16.6 1.4e-09 38.4 0.0 8.6 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN55853.1 - 3.1e-25 88.3 1.7 0.00021 21.5 0.0 6.1 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN55853.1 - 3.6e-09 36.0 0.7 0.11 11.4 0.0 5.0 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 RLN55853.1 - 4.8e-09 36.4 0.3 0.0014 18.5 0.0 3.7 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A NLE PF08154.12 RLN55853.1 - 4.2e-08 33.6 0.0 8.1e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 RLN55853.1 - 8.1e-07 28.1 0.2 2 6.9 0.2 4.7 3 2 2 5 5 5 4 Nucleoporin Nup120/160 PD40 PF07676.12 RLN55853.1 - 4.7e-05 23.2 5.1 2.1 8.4 0.0 4.7 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 RLN55853.1 - 0.00022 20.6 0.5 1.2 8.5 0.0 4.0 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.12 RLN55853.1 - 0.00034 18.8 0.6 0.041 11.9 0.1 2.4 2 1 1 3 3 3 2 IKI3 family Nucleoporin_N PF08801.11 RLN55853.1 - 0.001 17.9 0.1 0.4 9.4 0.0 2.3 2 0 0 2 2 2 2 Nup133 N terminal like DUF2140 PF09911.9 RLN55853.1 - 0.025 14.1 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) WD40_like PF17005.5 RLN55853.1 - 0.055 12.8 0.0 13 5.0 0.0 3.5 4 0 0 4 4 4 0 WD40-like domain PALB2_WD40 PF16756.5 RLN55853.1 - 0.057 12.3 3.2 3.1 6.6 0.2 2.8 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Coatomer_WDAD PF04053.14 RLN55853.1 - 0.063 12.3 0.0 0.17 10.9 0.0 1.7 1 0 0 1 1 1 0 Coatomer WD associated region Cytochrom_D1 PF02239.16 RLN55853.1 - 0.076 11.5 0.0 0.25 9.8 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain HPS3_N PF14761.6 RLN55853.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 CHAP PF05257.16 RLN55853.1 - 0.18 12.4 0.9 27 5.4 0.1 2.7 2 0 0 2 2 2 0 CHAP domain Proteasome_A_N PF10584.9 RLN55853.1 - 0.78 9.5 6.8 33 4.3 0.5 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Auxin_repressed PF05564.12 RLN55854.1 - 0.08 13.6 0.8 0.087 13.5 0.8 1.1 1 0 0 1 1 1 0 Dormancy/auxin associated protein Spt4 PF06093.13 RLN55855.1 - 8.5e-33 112.3 1.2 1.1e-32 112.0 1.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger HIPIP PF01355.17 RLN55855.1 - 0.27 11.6 4.5 0.33 11.3 1.5 2.0 1 1 1 2 2 2 0 High potential iron-sulfur protein SH3_3 PF08239.11 RLN55856.1 - 1e-05 25.7 0.0 0.018 15.3 0.0 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_4 PF06347.13 RLN55856.1 - 0.002 17.9 0.0 0.011 15.6 0.0 2.3 1 0 0 1 1 1 1 Bacterial SH3 domain eRF1_1 PF03463.15 RLN55858.1 - 5.7e-40 136.3 0.3 4.6e-19 68.7 0.0 2.4 2 0 0 2 2 2 2 eRF1 domain 1 eRF1_2 PF03464.15 RLN55858.1 - 1.9e-29 102.7 0.2 4.5e-29 101.5 0.2 1.7 1 0 0 1 1 1 1 eRF1 domain 2 NAD_binding_2 PF03446.15 RLN55858.1 - 5.5e-28 98.1 1.2 2.2e-27 96.2 0.3 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase eRF1_3 PF03465.15 RLN55858.1 - 2.3e-23 82.8 0.0 6.2e-23 81.4 0.0 1.8 1 0 0 1 1 1 1 eRF1 domain 3 NAD_binding_11 PF14833.6 RLN55858.1 - 4.1e-18 65.8 0.1 1e-17 64.5 0.1 1.7 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 RLN55858.1 - 0.00081 18.8 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 RLN55858.1 - 0.00094 19.7 0.0 0.0025 18.4 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 RLN55858.1 - 0.0032 17.4 0.0 0.0069 16.3 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 RLN55858.1 - 0.01 15.4 0.0 0.034 13.7 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HTH_57 PF18679.1 RLN55858.1 - 0.032 14.6 0.0 0.099 13.0 0.0 1.8 1 0 0 1 1 1 0 ThcOx helix turn helix domain TrkA_N PF02254.18 RLN55858.1 - 0.11 12.8 0.0 0.35 11.1 0.0 1.9 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 RLN55858.1 - 0.16 11.6 0.0 0.55 9.9 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Sedlin_N PF04628.13 RLN55859.1 - 7.2e-24 84.4 0.0 1.4e-23 83.5 0.0 1.4 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 RLN55859.1 - 0.013 15.5 0.0 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 Sybindin-like family Sugar_tr PF00083.24 RLN55860.1 - 7e-84 282.3 22.7 9.4e-84 281.8 22.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN55860.1 - 5.4e-23 81.5 50.9 5.5e-22 78.2 28.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 RLN55860.1 - 0.0014 17.1 4.3 0.0025 16.3 4.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Eno-Rase_NADH_b PF12242.8 RLN55860.1 - 0.067 13.0 0.5 0.17 11.7 0.5 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Dimer_Tnp_hAT PF05699.14 RLN55861.1 - 1.1e-08 34.8 0.1 8.7e-08 31.9 0.0 2.4 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 RLN55861.1 - 3.1e-07 30.3 1.7 3.6e-07 30.1 0.3 1.8 2 0 0 2 2 2 1 BED zinc finger ADH_N PF08240.12 RLN55873.1 - 7.9e-27 93.3 2.6 1.6e-26 92.3 2.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN55873.1 - 4e-17 62.4 0.9 6.9e-17 61.6 0.9 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN55873.1 - 1.1e-05 26.4 0.1 1.8e-05 25.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN55873.1 - 0.0002 20.8 0.6 0.00085 18.7 0.2 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KR PF08659.10 RLN55873.1 - 0.053 13.4 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 KR domain AlaDh_PNT_C PF01262.21 RLN55873.1 - 0.094 12.0 1.1 0.15 11.3 1.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain OST3_OST6 PF04756.13 RLN55888.1 - 9.8e-66 222.1 0.2 1.3e-65 221.7 0.2 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF1350 PF07082.11 RLN55888.1 - 0.039 13.3 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) Thioredoxin PF00085.20 RLN55888.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin DUF2534 PF10749.9 RLN55888.1 - 0.55 10.4 4.4 0.19 11.9 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2534) LEAP-2 PF07359.11 RLN55888.1 - 0.56 10.1 2.1 2.2 8.2 0.1 2.6 3 0 0 3 3 3 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) OATP PF03137.20 RLN55888.1 - 0.72 8.1 5.6 0.058 11.7 0.9 1.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF1336 PF07059.12 RLN55889.1 - 3.8e-68 230.0 0.0 5.5e-68 229.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) START PF01852.19 RLN55889.1 - 2e-20 73.1 0.2 4.4e-20 72.0 0.2 1.5 1 0 0 1 1 1 1 START domain PH PF00169.29 RLN55889.1 - 4.6e-06 27.1 0.0 1.3e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 PH domain Polyketide_cyc2 PF10604.9 RLN55889.1 - 0.0044 17.3 0.1 0.014 15.7 0.1 1.8 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport TCR PF03638.15 RLN55890.1 - 2.5e-25 88.5 51.8 1e-12 48.1 20.4 2.3 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain F-box-like PF12937.7 RLN55890.1 - 5.1e-06 26.3 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RLN55890.1 - 0.0084 16.0 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain Sugar_tr PF00083.24 RLN55902.1 - 2.8e-21 75.9 8.9 3.1e-21 75.8 8.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Pro_isomerase PF00160.21 RLN55910.1 - 1e-25 90.9 0.3 1.2e-11 45.2 0.0 2.6 1 1 1 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Tic110 PF16940.5 RLN55910.1 - 0.091 11.2 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter FTP PF07504.13 RLN55910.1 - 0.1 12.5 0.2 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif MFS_1 PF07690.16 RLN55911.1 - 6.3e-07 28.6 17.8 6.3e-07 28.6 17.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.19 RLN55924.1 - 6.4e-17 61.8 6.9 1.2e-13 51.1 1.8 2.7 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 RLN55924.1 - 1.6e-06 27.4 0.0 6.4e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 RLN55924.1 - 3.7e-06 26.8 0.4 8.3e-06 25.6 0.4 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RLN55924.1 - 1.4e-05 25.2 2.4 4.1e-05 23.7 2.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 RLN55924.1 - 3.9e-05 23.0 1.0 5.4e-05 22.6 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 RLN55924.1 - 0.00026 20.0 8.9 0.01 14.7 1.3 2.6 3 0 0 3 3 3 2 Tryptophan halogenase HI0933_like PF03486.14 RLN55924.1 - 0.0036 16.1 1.7 0.016 13.9 1.0 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 RLN55924.1 - 0.015 14.4 2.2 0.023 13.8 2.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 RLN55924.1 - 0.039 13.0 2.8 0.048 12.7 0.3 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox PF00070.27 RLN55924.1 - 0.063 13.8 2.4 0.099 13.2 0.9 2.2 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 RLN55924.1 - 0.063 13.1 0.4 0.11 12.3 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 RLN55924.1 - 0.086 12.1 0.5 0.15 11.3 0.5 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 RLN55924.1 - 0.24 10.4 4.7 0.4 9.7 4.7 1.4 1 0 0 1 1 1 0 FAD binding domain Not1 PF04054.15 RLN55931.1 - 7.3e-133 443.0 0.0 4e-132 440.6 0.0 1.9 1 1 0 1 1 1 1 CCR4-Not complex component, Not1 FANCI_S2 PF14676.6 RLN55931.1 - 0.14 12.4 0.0 0.37 11.1 0.0 1.7 1 0 0 1 1 1 0 FANCI solenoid 2 Aldedh PF00171.22 RLN55932.1 - 8.7e-108 360.8 1.0 9.8e-108 360.6 1.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 RLN55933.1 - 3.5e-19 68.7 0.0 4.1e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Laminin_G_3 PF13385.6 RLN55945.1 - 2.6e-13 50.4 0.2 5.6e-10 39.6 0.2 2.7 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Laminin_B PF00052.18 RLN55945.1 - 3.6e-06 26.9 0.0 1.7e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Laminin B (Domain IV) Calx-beta PF03160.14 RLN55945.1 - 1.1e-05 25.5 0.1 3.3e-05 24.0 0.1 1.9 1 0 0 1 1 1 1 Calx-beta domain Pentaxin PF00354.17 RLN55945.1 - 0.00059 19.6 0.0 0.01 15.5 0.0 2.5 2 0 0 2 2 2 1 Pentaxin family Thoc2 PF11732.8 RLN55945.1 - 0.13 12.3 0.1 0.38 10.9 0.1 1.8 1 0 0 1 1 1 0 Transcription- and export-related complex subunit GH131_N PF18271.1 RLN55946.1 - 5.1e-35 121.4 0.3 1e-34 120.4 0.3 1.5 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain DUF3640 PF12342.8 RLN55946.1 - 0.16 11.8 0.1 0.29 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3640) EI24 PF07264.11 RLN55958.1 - 1.8e-25 90.2 17.6 2.2e-25 89.9 17.6 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) TctB PF07331.11 RLN55958.1 - 0.58 10.4 15.2 0.046 14.0 7.1 2.5 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Adeno_E3_CR2 PF02439.15 RLN55958.1 - 1.6 8.5 4.5 6.5 6.6 1.1 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF2070 PF09843.9 RLN55958.1 - 8.9 4.5 11.5 12 4.1 11.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Pkinase_Tyr PF07714.17 RLN55981.1 - 1.2e-43 149.3 0.0 1.7e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN55981.1 - 7.4e-39 133.7 0.0 1.4e-38 132.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 RLN55981.1 - 0.01 14.6 0.0 0.019 13.8 0.0 1.5 1 1 0 1 1 1 0 Fungal protein kinase HIG_1_N PF04588.13 RLN56016.1 - 2.7e-06 27.5 2.8 1.6e-05 25.0 0.4 2.4 2 0 0 2 2 2 1 Hypoxia induced protein conserved region ENOD93 PF03386.14 RLN56016.1 - 0.11 12.4 0.3 0.21 11.5 0.3 1.4 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein DUF4516 PF14990.6 RLN56016.1 - 5.6 6.8 7.1 3.7 7.3 1.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) ABC_tran PF00005.27 RLN56017.1 - 1e-11 45.5 0.0 1.4e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 RLN56017.1 - 3.6e-05 24.2 0.0 4.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 RLN56017.1 - 6.8e-05 22.5 0.9 0.00028 20.6 0.4 2.1 1 1 1 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN56017.1 - 0.00021 20.9 0.1 0.00039 20.0 0.1 1.4 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 RLN56017.1 - 0.00041 20.3 0.0 0.00042 20.2 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 RLN56017.1 - 0.0018 18.8 0.0 0.0035 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RLN56017.1 - 0.0021 18.6 0.0 0.0051 17.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RLN56017.1 - 0.0043 17.3 0.0 0.0073 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 RLN56017.1 - 0.0067 16.4 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 RLN56017.1 - 0.013 15.7 0.0 0.032 14.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 RLN56017.1 - 0.013 15.3 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 RLN56017.1 - 0.024 14.9 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 RLN56017.1 - 0.032 14.7 0.0 0.049 14.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 RLN56017.1 - 0.038 14.4 0.1 0.099 13.0 0.0 1.8 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 RLN56017.1 - 0.039 14.1 0.1 0.064 13.4 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain NTPase_1 PF03266.15 RLN56017.1 - 0.04 13.8 0.0 0.088 12.7 0.0 1.7 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.14 RLN56017.1 - 0.069 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.17 RLN56017.1 - 0.074 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase SMC_N PF02463.19 RLN56017.1 - 0.085 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 RLN56017.1 - 0.09 12.5 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 RLN56017.1 - 0.092 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 RLN56017.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 RLN56017.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Cytidylate_kin PF02224.18 RLN56017.1 - 0.13 12.0 0.3 0.21 11.3 0.3 1.3 1 0 0 1 1 1 0 Cytidylate kinase cobW PF02492.19 RLN56017.1 - 0.14 11.7 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Dickkopf_N PF04706.12 RLN56018.1 - 0.092 13.2 8.0 0.61 10.6 0.4 2.5 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region REJ PF02010.15 RLN56019.1 - 2.7e-63 214.4 15.3 2.8e-60 204.4 3.6 3.3 2 1 1 3 3 3 2 REJ domain GPS PF01825.21 RLN56019.1 - 1.5e-09 38.2 4.3 1.5e-09 38.2 4.3 2.0 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif TMEM154 PF15102.6 RLN56019.1 - 0.075 12.9 0.1 0.075 12.9 0.1 2.7 3 0 0 3 3 3 0 TMEM154 protein family EGF_2 PF07974.13 RLN56019.1 - 0.66 10.4 13.4 1.4 9.4 13.4 1.6 1 0 0 1 1 1 0 EGF-like domain PAN_1 PF00024.26 RLN56035.1 - 5.7e-25 87.1 18.7 4.1e-07 29.9 1.5 4.9 4 0 0 4 4 4 4 PAN domain PAN_4 PF14295.6 RLN56035.1 - 1.5e-18 66.4 40.7 1.4e-09 37.7 2.7 5.4 5 0 0 5 5 5 4 PAN domain PAN_2 PF08276.11 RLN56035.1 - 0.014 15.5 0.3 0.014 15.5 0.3 5.1 5 0 0 5 5 5 0 PAN-like domain Trypsin_2 PF13365.6 RLN56058.1 - 1.1e-11 45.8 0.0 3.9e-11 44.1 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 RLN56058.1 - 0.0047 16.8 0.0 0.0089 15.9 0.0 1.4 1 0 0 1 1 1 1 Trypsin JmjN PF02375.17 RLN56085.1 - 9.9e-18 63.8 0.2 1.7e-17 63.0 0.2 1.4 1 0 0 1 1 1 1 jmjN domain ARID PF01388.21 RLN56085.1 - 7.8e-15 55.3 0.0 1.5e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain MSP1_C PF07462.11 RLN56085.1 - 0.5 9.0 2.1 0.74 8.4 2.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PX PF00787.24 RLN56087.1 - 0.17 11.8 0.6 1.6 8.7 0.4 2.3 1 1 0 1 1 1 0 PX domain PX PF00787.24 RLN56088.1 - 0.2 11.7 0.3 0.46 10.5 0.3 1.6 1 1 0 1 1 1 0 PX domain USP7_ICP0_bdg PF12436.8 RLN56091.1 - 4.5e-53 180.0 0.0 1.9e-48 164.9 0.0 3.7 1 1 1 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.29 RLN56091.1 - 1.9e-48 165.2 0.1 3.5e-48 164.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 RLN56091.1 - 6.4e-29 101.1 0.0 2.5e-28 99.2 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.6 RLN56091.1 - 8.8e-21 74.8 0.0 2.4e-20 73.4 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 RLN56091.1 - 0.0005 19.8 0.0 0.18 11.5 0.0 3.0 3 0 0 3 3 3 1 Ubiquitin family Peptidase_C98 PF15499.6 RLN56091.1 - 0.0066 15.9 0.3 0.04 13.4 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase UN_NPL4 PF11543.8 RLN56091.1 - 0.015 15.7 0.0 24 5.5 0.0 3.6 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 Ubiquitin_2 PF14560.6 RLN56091.1 - 0.066 13.7 0.0 22 5.6 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin-like domain Podoplanin PF05808.11 RLN56091.1 - 0.18 11.9 9.1 0.24 11.5 1.8 2.6 2 0 0 2 2 2 0 Podoplanin AMP-binding PF00501.28 RLN56092.1 - 7.5e-36 123.6 0.0 1.2e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Methyltransf_11 PF08241.12 RLN56104.1 - 2.2e-14 53.9 0.1 2.9e-14 53.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN56104.1 - 4.5e-12 46.5 0.1 6.1e-12 46.1 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN56104.1 - 7.8e-11 42.6 0.1 1e-10 42.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN56104.1 - 2.3e-10 40.6 0.0 2.8e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN56104.1 - 1.8e-09 37.6 0.1 2.1e-09 37.3 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 RLN56104.1 - 1.8e-05 24.2 0.0 2.3e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 RLN56104.1 - 8.2e-05 22.1 0.0 9.2e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 RLN56104.1 - 0.0013 18.3 0.0 0.0019 17.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 RLN56104.1 - 0.0037 17.2 0.0 0.0054 16.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN56104.1 - 0.0047 16.3 0.0 0.0059 16.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 RLN56104.1 - 0.013 15.1 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 RLN56104.1 - 0.091 11.7 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PA PF02225.22 RLN56105.1 - 3.1e-05 23.9 0.2 0.00019 21.4 0.0 2.3 2 0 0 2 2 2 1 PA domain Coatomer_WDAD PF04053.14 RLN56106.1 - 1.7e-122 409.7 0.0 2.5e-122 409.2 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 RLN56106.1 - 1.4e-111 373.2 0.7 4.1e-111 371.6 0.7 1.6 1 1 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 RLN56106.1 - 1.1e-41 139.9 19.6 1.3e-08 35.3 0.2 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN56106.1 - 1.8e-08 34.6 2.5 0.00016 21.9 0.0 5.4 4 2 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain CBFB_NFYA PF02045.15 RLN56107.1 - 3.2e-27 94.9 7.5 3.2e-27 94.9 7.5 1.5 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B MCD PF05292.11 RLN56108.1 - 1.2e-62 211.8 0.1 3.1e-62 210.5 0.1 1.7 1 1 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain cNMP_binding PF00027.29 RLN56108.1 - 6.2e-05 23.0 0.0 0.00032 20.7 0.0 2.3 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain WD40 PF00400.32 RLN56109.1 - 1.5e-45 152.2 11.6 3.4e-07 30.8 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.11 RLN56109.1 - 2.1e-14 52.8 7.5 4.3e-14 51.8 7.5 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 RLN56109.1 - 6e-10 39.3 0.6 0.021 15.1 0.0 5.2 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN56109.1 - 1.6 7.3 6.6 12 4.4 0.2 3.8 2 1 3 5 5 5 0 Nucleoporin Nup120/160 PDZ PF00595.24 RLN56110.1 - 0.00054 20.3 0.0 0.00087 19.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RLN56110.1 - 0.0027 17.5 0.0 0.0055 16.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain RskA PF10099.9 RLN56110.1 - 0.09 13.1 6.2 0.12 12.7 6.2 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4959 PF16323.5 RLN56110.1 - 0.15 12.4 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4959) PhoLip_ATPase_C PF16212.5 RLN56111.1 - 4.2e-55 187.2 10.8 4.2e-55 187.2 10.8 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RLN56111.1 - 6.4e-19 67.4 1.5 1.5e-18 66.2 1.5 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RLN56111.1 - 2.7e-12 47.4 1.5 9.6e-07 29.3 0.7 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN56111.1 - 6.7e-08 32.5 0.0 1.8e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RLN56111.1 - 1.1e-05 25.0 0.0 1.1e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RLN56111.1 - 0.0037 17.1 0.0 0.0083 15.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 RLN56111.1 - 0.009 16.1 0.0 0.16 12.1 0.0 2.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 RLN56111.1 - 0.03 14.7 0.0 9.5 6.6 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ion_trans PF00520.31 RLN56112.1 - 2.3e-48 164.5 5.9 9.2e-27 93.8 1.2 2.4 2 0 0 2 2 2 2 Ion transport protein cNMP_binding PF00027.29 RLN56112.1 - 2.6e-33 113.9 0.0 1.1e-17 63.8 0.0 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 RLN56112.1 - 1.5e-17 63.3 12.5 1.4e-08 34.6 2.9 2.8 2 0 0 2 2 2 2 Ion channel Spc24 PF08286.11 RLN56113.1 - 0.013 15.7 1.9 0.037 14.3 1.9 1.8 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Ank_3 PF13606.6 RLN56113.1 - 0.16 12.6 0.2 21 6.1 0.0 3.2 2 0 0 2 2 2 0 Ankyrin repeat TipAS PF07739.13 RLN56113.1 - 0.21 12.1 2.4 0.78 10.3 1.6 2.3 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain APG6_N PF17675.1 RLN56113.1 - 0.95 10.0 15.2 0.11 13.0 8.5 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region LINES_N PF14694.6 RLN56114.1 - 1.1e-17 64.5 0.2 1.1e-17 64.5 0.2 1.5 2 0 0 2 2 2 1 Lines N-terminus LINES_C PF14695.6 RLN56114.1 - 1.4e-13 50.1 0.3 4.4e-13 48.4 0.3 2.0 1 0 0 1 1 1 1 Lines C-terminus Helicase_C PF00271.31 RLN56115.1 - 4.6e-14 52.7 0.0 1.5e-13 51.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain R3H PF01424.22 RLN56115.1 - 1.5e-08 34.5 0.0 3.6e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 R3H domain DEAD PF00270.29 RLN56115.1 - 5.9e-08 32.7 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ATPase PF06745.13 RLN56115.1 - 0.046 13.1 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 RLN56115.1 - 0.076 13.4 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Anti-TRAP PF15777.5 RLN56115.1 - 0.087 12.8 0.3 0.2 11.6 0.3 1.5 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein AAA_14 PF13173.6 RLN56115.1 - 0.16 12.0 0.1 5.2 7.1 0.1 2.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RLN56115.1 - 0.17 11.4 0.0 0.5 9.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 RLN56115.1 - 0.21 12.1 0.0 0.44 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Na_Ca_ex PF01699.24 RLN56116.1 - 3e-43 147.4 33.4 3.7e-23 82.2 12.7 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein zf-HC5HC2H_2 PF13832.6 RLN56118.1 - 0.0026 17.9 0.4 0.0073 16.4 0.4 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain PHD PF00628.29 RLN56118.1 - 0.031 14.2 3.0 0.056 13.3 3.0 1.4 1 0 0 1 1 1 0 PHD-finger DUF2368 PF10166.9 RLN56118.1 - 8 6.1 12.9 0.97 9.0 7.6 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) CLTH PF10607.9 RLN56119.1 - 4e-25 88.4 0.1 5e-25 88.1 0.1 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 RLN56119.1 - 1.6e-06 27.8 0.1 6e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 LisH Spc7 PF08317.11 RLN56125.1 - 7.3e-05 21.8 77.4 0.0057 15.6 23.2 4.2 1 1 3 4 4 4 3 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 RLN56125.1 - 0.0001 22.4 85.0 0.0012 18.9 20.8 6.2 2 2 4 6 6 6 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.6 RLN56125.1 - 0.00016 21.4 60.9 0.002 17.9 21.7 5.1 2 2 3 5 5 5 3 Domain of unknown function (DUF4201) Atg14 PF10186.9 RLN56125.1 - 0.00036 19.7 15.7 0.00036 19.7 15.7 3.8 1 1 2 3 3 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 Filament PF00038.21 RLN56125.1 - 0.00036 20.2 41.7 0.00036 20.2 41.7 3.7 1 1 1 3 3 3 1 Intermediate filament protein Tup_N PF08581.10 RLN56125.1 - 0.0012 19.1 7.4 0.0012 19.1 7.4 7.4 3 2 4 7 7 6 2 Tup N-terminal NPV_P10 PF05531.12 RLN56125.1 - 0.0038 17.7 22.4 0.096 13.2 0.7 5.9 3 3 2 5 5 5 1 Nucleopolyhedrovirus P10 protein Fez1 PF06818.15 RLN56125.1 - 0.0039 17.7 19.3 0.0039 17.7 19.3 4.2 1 1 3 4 4 4 2 Fez1 DUF5082 PF16888.5 RLN56125.1 - 0.0043 17.3 11.3 0.0043 17.3 11.3 5.9 2 1 3 6 6 6 2 Domain of unknown function (DUF5082) YkyA PF10368.9 RLN56125.1 - 0.0051 16.5 24.9 0.0051 16.5 24.9 5.0 1 1 2 5 5 3 1 Putative cell-wall binding lipoprotein Mod_r PF07200.13 RLN56125.1 - 0.012 15.7 63.5 0.095 12.8 13.8 5.7 2 2 3 5 5 5 0 Modifier of rudimentary (Mod(r)) protein GAS PF13851.6 RLN56125.1 - 0.055 12.8 69.6 0.019 14.3 9.1 4.8 2 2 3 5 5 5 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 RLN56125.1 - 0.095 12.7 42.8 0.24 11.4 3.0 5.6 2 2 4 6 6 6 0 Protein of unknown function (DUF1664) DUF4200 PF13863.6 RLN56125.1 - 0.13 12.7 75.8 0.12 12.8 23.0 7.0 3 1 3 6 6 6 0 Domain of unknown function (DUF4200) Pox_A_type_inc PF04508.12 RLN56125.1 - 0.22 11.5 0.1 0.22 11.5 0.1 6.5 7 0 0 7 7 5 0 Viral A-type inclusion protein repeat DASH_Dad4 PF08650.10 RLN56125.1 - 0.33 10.9 16.8 3.6 7.6 0.6 5.7 4 2 2 6 6 6 0 DASH complex subunit Dad4 APG6_N PF17675.1 RLN56125.1 - 0.38 11.3 92.8 0.92 10.0 16.1 5.6 1 1 3 4 4 4 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 RLN56125.1 - 0.39 11.0 83.8 0.13 12.5 17.4 6.4 3 2 3 6 6 6 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 RLN56125.1 - 0.86 9.7 79.8 0.28 11.2 17.3 6.6 1 1 3 6 6 6 0 TPR/MLP1/MLP2-like protein LIF_OSM PF01291.17 RLN56125.1 - 1.1 9.4 5.4 0.34 11.1 0.5 2.5 2 1 1 3 3 3 0 LIF / OSM family Seryl_tRNA_N PF02403.22 RLN56125.1 - 2.3 8.5 54.7 0.35 11.1 11.3 5.6 2 2 4 6 6 6 0 Seryl-tRNA synthetase N-terminal domain FERM_M PF00373.18 RLN56125.1 - 2.6 8.5 7.4 3.1 8.2 1.8 2.6 2 1 0 2 2 2 0 FERM central domain Golgin_A5 PF09787.9 RLN56125.1 - 3 7.2 79.8 0.072 12.5 23.2 4.0 1 1 3 4 4 4 0 Golgin subfamily A member 5 DUF3584 PF12128.8 RLN56125.1 - 4.3 4.7 70.3 0.0092 13.6 37.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) ADIP PF11559.8 RLN56125.1 - 5.1 7.2 66.0 0.035 14.2 9.3 6.4 2 2 4 6 6 6 0 Afadin- and alpha -actinin-Binding DUF948 PF06103.11 RLN56125.1 - 6 7.2 23.0 0.057 13.7 1.1 5.0 5 1 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Jnk-SapK_ap_N PF09744.9 RLN56125.1 - 7.3 6.8 82.0 0.027 14.7 11.1 5.6 1 1 5 6 6 6 0 JNK_SAPK-associated protein-1 ERM PF00769.19 RLN56125.1 - 7.9 6.2 88.2 0.096 12.5 25.4 4.1 1 1 3 4 4 4 0 Ezrin/radixin/moesin family DcpS_C PF11969.8 RLN56126.1 - 9.6e-18 64.7 0.0 2e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 RLN56126.1 - 1.6e-10 41.6 1.9 6.3e-10 39.7 1.9 2.0 1 1 0 1 1 1 1 HIT domain Malate_DH PF12434.8 RLN56126.1 - 0.21 11.7 0.8 0.58 10.2 0.8 1.7 1 0 0 1 1 1 0 Malate dehydrogenase enzyme Apt1 PF10351.9 RLN56126.1 - 8 5.2 10.4 0.31 9.8 4.8 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain PPR_2 PF13041.6 RLN56127.1 - 5.1e-11 42.6 8.1 1.6 9.0 0.0 9.1 7 2 2 9 9 9 4 PPR repeat family PPR PF01535.20 RLN56127.1 - 6.1e-08 32.4 7.7 2.4 8.6 0.0 8.6 9 0 0 9 9 9 2 PPR repeat PPR_1 PF12854.7 RLN56127.1 - 0.012 15.3 0.9 1.8 8.3 0.0 4.8 6 0 0 6 6 6 0 PPR repeat RecG_N PF17190.4 RLN56127.1 - 0.039 14.7 0.4 11 6.8 0.3 3.8 3 0 0 3 3 3 0 RecG N-terminal helical domain PPR_3 PF13812.6 RLN56127.1 - 0.042 13.9 6.9 4.1 7.6 0.1 5.9 7 1 1 8 8 8 0 Pentatricopeptide repeat domain LAGLIDADG_3 PF14528.6 RLN56127.1 - 0.062 13.6 0.0 0.23 11.8 0.0 2.0 1 0 0 1 1 1 0 LAGLIDADG-like domain TFR_dimer PF04253.15 RLN56127.1 - 0.082 13.0 0.1 0.38 10.9 0.1 2.2 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain PPR_long PF17177.4 RLN56128.1 - 0.002 17.5 0.0 13 5.0 0.0 4.3 2 2 2 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 RLN56128.1 - 0.019 15.1 0.0 43 4.4 0.0 4.6 4 0 0 4 4 4 0 PPR repeat family Pkinase PF00069.25 RLN56129.1 - 6.2e-66 222.5 0.0 7.3e-66 222.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN56129.1 - 5.5e-18 65.2 0.0 8.2e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN56129.1 - 3.5e-06 27.1 0.1 1.1e-05 25.5 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN56129.1 - 0.011 14.6 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 RLN56129.1 - 0.021 14.2 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RLN56129.1 - 0.036 13.7 0.1 0.061 12.9 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 RLN56129.1 - 0.098 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 RLN56129.1 - 0.14 11.7 0.3 0.26 10.9 0.3 1.6 1 1 0 1 1 1 0 RIO1 family MHB PF16525.5 RLN56130.1 - 0.042 14.1 0.0 0.092 13.0 0.0 1.6 1 1 0 1 1 1 0 Haemophore, haem-binding FAD_binding_1 PF00667.20 RLN56132.1 - 3.4e-23 82.4 0.0 5.7e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain His_Phos_2 PF00328.22 RLN56132.1 - 2.7e-14 53.3 0.0 6.6e-13 48.8 0.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NAD_binding_1 PF00175.21 RLN56132.1 - 9.8e-13 48.7 0.0 2.4e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Oxidored-like PF09791.9 RLN56132.1 - 5.8e-06 25.9 1.2 1.7e-05 24.4 1.2 1.8 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal NAD_binding_6 PF08030.12 RLN56132.1 - 0.021 14.9 0.0 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Crystall_3 PF08964.10 RLN56145.1 - 0.087 13.0 1.4 5.3 7.3 0.0 3.0 3 0 0 3 3 3 0 Beta/Gamma crystallin lci PF12197.8 RLN56146.1 - 0.66 9.8 3.6 1.4 8.7 0.0 2.6 3 0 0 3 3 3 0 Bacillus cereus group antimicrobial protein CHDCT2 PF08074.11 RLN56223.1 - 0.0057 16.8 1.1 0.0088 16.2 0.1 1.8 2 0 0 2 2 2 1 CHDCT2 (NUC038) domain Cdh1_DBD_1 PF18196.1 RLN56223.1 - 4.1 7.8 8.1 3.8 7.8 0.0 3.5 3 0 0 3 3 3 0 Chromodomain helicase DNA-binding domain 1 PGP_phosphatase PF09419.10 RLN56224.1 - 3.1e-31 108.3 0.0 1.2e-29 103.1 0.0 2.7 1 1 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 RLN56224.1 - 0.00053 20.0 0.0 0.00094 19.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hemerythrin PF01814.23 RLN56225.1 - 0.074 13.7 0.2 3.3 8.4 0.0 2.3 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain SNF2_N PF00176.23 RLN56226.1 - 4e-60 203.4 1.6 7.9e-60 202.4 1.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain PHD PF00628.29 RLN56226.1 - 9.4e-28 95.9 66.2 7.3e-10 38.6 6.2 6.8 6 0 0 6 6 6 5 PHD-finger Helicase_C PF00271.31 RLN56226.1 - 4.4e-18 65.6 0.0 9.8e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 RLN56226.1 - 3.1e-16 59.2 0.0 6.5e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Bromodomain zf-HC5HC2H PF13771.6 RLN56226.1 - 2e-14 53.6 54.3 3.3e-12 46.5 3.1 7.1 6 1 1 7 7 7 3 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 RLN56226.1 - 1.9e-11 44.1 44.4 7.1e-09 35.8 2.1 6.7 3 2 3 6 6 6 4 PHD-zinc-finger like domain Chromo PF00385.24 RLN56226.1 - 1.3e-09 37.8 1.4 2.7e-06 27.2 0.0 3.5 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 RLN56226.1 - 9.1e-09 35.5 0.0 2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 RLN56226.1 - 1.7e-05 24.1 0.0 4.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 RLN56226.1 - 0.00011 22.0 0.0 0.00034 20.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase PHD_2 PF13831.6 RLN56226.1 - 0.00064 19.2 41.9 0.0009 18.7 0.6 5.6 6 0 0 6 6 5 3 PHD-finger SWI2_SNF2 PF18766.1 RLN56226.1 - 0.016 14.9 0.0 0.04 13.6 0.0 1.6 1 1 0 1 1 1 0 SWI2/SNF2 ATPase PDZ PF00595.24 RLN56226.1 - 0.04 14.3 0.0 0.09 13.1 0.0 1.6 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 RLN56226.1 - 0.083 12.8 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 PDZ domain Oxidored_q6 PF01058.22 RLN56284.1 - 1.7e-65 218.7 0.0 1.6e-20 73.3 0.0 3.1 3 0 0 3 3 3 3 NADH ubiquinone oxidoreductase, 20 Kd subunit Secapin PF17521.2 RLN56284.1 - 2.3e-07 30.5 10.6 0.087 12.6 0.0 5.1 6 0 0 6 6 6 3 Honey bee peptides DEC-1_C PF04626.13 RLN56284.1 - 0.0052 17.2 12.8 1.7 9.1 1.1 3.2 3 0 0 3 3 3 3 Dec-1 protein, C terminal region DUF2536 PF10750.9 RLN56284.1 - 0.0063 16.4 0.5 33 4.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2536) FrpC PF06901.12 RLN56284.1 - 0.035 13.7 0.3 47 3.5 0.0 3.0 3 0 0 3 3 3 0 RTX iron-regulated protein FrpC PhoH PF02562.16 RLN56284.1 - 0.046 13.2 0.0 56 3.1 0.0 3.1 3 0 0 3 3 3 0 PhoH-like protein T2SSF PF00482.23 RLN56284.1 - 0.17 11.9 0.0 88 3.1 0.0 3.1 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F DUF4442 PF14539.6 RLN56285.1 - 1.2e-31 109.6 0.1 1.4e-31 109.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) Oxidored_q6 PF01058.22 RLN56287.1 - 1.9e-21 76.3 0.0 4.4e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Usp PF00582.26 RLN56287.1 - 0.00022 21.8 0.1 0.47 11.0 0.0 2.6 2 0 0 2 2 2 2 Universal stress protein family FAD_binding_7 PF03441.14 RLN56323.1 - 1.8e-75 252.9 1.1 2.6e-75 252.4 1.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 RLN56323.1 - 9e-37 126.6 0.6 2.3e-36 125.3 0.6 1.7 1 1 0 1 1 1 1 DNA photolyase FAM176 PF14851.6 RLN56323.1 - 1 9.0 3.5 1.9 8.1 3.5 1.4 1 0 0 1 1 1 0 FAM176 family MiAMP1 PF09117.10 RLN56324.1 - 0.13 12.5 0.4 0.52 10.6 0.1 1.9 1 1 1 2 2 2 0 MiAMP1 FAD_binding_7 PF03441.14 RLN56326.1 - 1e-67 227.5 0.4 1.5e-67 227.0 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 RLN56326.1 - 1.7e-32 112.7 0.2 3e-32 111.9 0.2 1.3 1 0 0 1 1 1 1 DNA photolyase Herpes_pp85 PF04637.12 RLN56326.1 - 6.6 5.0 6.7 9.6 4.5 6.7 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) zf-RING_2 PF13639.6 RLN56327.1 - 2.3e-11 43.8 4.9 3.4e-11 43.3 4.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN56327.1 - 4.6e-10 39.2 4.3 7.2e-10 38.6 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN56327.1 - 4.6e-09 36.0 3.1 6.8e-09 35.5 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN56327.1 - 3.6e-08 33.6 7.3 9.2e-08 32.3 7.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 RLN56327.1 - 6.4e-06 25.9 2.9 1.1e-05 25.1 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN56327.1 - 5.7e-05 23.1 2.5 0.0001 22.2 2.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 RLN56327.1 - 0.00014 21.5 3.2 0.00036 20.2 3.2 1.8 1 1 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 RLN56327.1 - 0.00029 20.4 1.7 0.00047 19.7 1.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 RLN56327.1 - 0.0016 18.3 4.3 0.0042 17.0 4.5 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 RLN56327.1 - 0.0091 16.0 3.7 0.024 14.7 3.7 1.6 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 RLN56327.1 - 0.014 15.3 5.8 0.041 13.7 5.9 1.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zinc_ribbon_16 PF17034.5 RLN56327.1 - 0.077 13.2 1.5 0.091 13.0 0.7 1.4 1 1 0 1 1 1 0 Zinc-ribbon like family zf-HC5HC2H PF13771.6 RLN56327.1 - 0.22 11.8 1.7 0.23 11.8 0.2 1.8 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-RING-like PF08746.11 RLN56327.1 - 0.29 11.5 4.0 0.62 10.4 4.1 1.5 1 1 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 RLN56327.1 - 0.32 10.8 3.3 0.61 9.9 3.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 RLN56327.1 - 0.47 10.7 4.7 3 8.1 4.9 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 RLN56327.1 - 1.8 8.8 6.3 10 6.4 6.3 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Anoctamin PF04547.12 RLN56328.1 - 6.8e-85 285.6 9.2 8.9e-85 285.2 9.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Ank_2 PF12796.7 RLN56328.1 - 2.5e-16 60.0 0.1 9.7e-05 22.9 0.0 5.2 4 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 RLN56328.1 - 2.8e-06 27.5 6.1 3 8.4 0.0 5.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 RLN56328.1 - 5.1e-06 26.9 3.3 0.53 10.9 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN56328.1 - 7.4e-06 25.9 0.7 12 6.8 0.0 5.7 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 RLN56328.1 - 0.034 14.5 5.0 6.8 7.1 0.0 4.5 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Anoct_dimer PF16178.5 RLN56328.1 - 0.13 12.0 1.8 0.43 10.3 0.1 2.3 2 1 1 3 3 3 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin FYVE_2 PF02318.16 RLN56328.1 - 0.57 10.4 5.0 1.4 9.1 1.8 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger DUF4229 PF14012.6 RLN56328.1 - 1.4 9.1 8.3 0.4 10.8 2.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) S-methyl_trans PF02574.16 RLN56329.1 - 6.6e-64 216.3 0.0 7.6e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase MFS_1_like PF12832.7 RLN56330.1 - 2.9e-63 214.0 19.6 5.1e-63 213.2 19.6 1.4 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RLN56330.1 - 2.6e-19 69.4 33.6 2.9e-19 69.2 27.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 RLN56330.1 - 1.3e-16 60.6 15.7 1.8e-16 60.2 15.7 1.0 1 0 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 RLN56330.1 - 2.7e-14 52.8 14.8 6.9e-14 51.4 14.8 1.6 1 1 0 1 1 1 1 LacY proton/sugar symporter MFS_2 PF13347.6 RLN56330.1 - 8.5e-07 27.9 20.0 0.00021 20.0 7.3 2.5 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.13 RLN56330.1 - 0.12 10.7 17.2 0.34 9.3 17.2 1.6 1 1 0 1 1 1 0 Transmembrane secretion effector zf-RING_2 PF13639.6 RLN56331.1 - 2.3e-11 43.9 10.7 3.8e-11 43.1 10.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RLN56331.1 - 1.3e-09 38.2 7.9 2.5e-09 37.3 7.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 RLN56331.1 - 1.7e-08 34.1 5.6 2.4e-08 33.7 5.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN56331.1 - 9.1e-08 31.8 10.6 1.6e-07 31.0 10.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN56331.1 - 1.6e-07 30.9 7.6 4.4e-07 29.5 7.6 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 RLN56331.1 - 2.3e-07 30.5 10.0 4.1e-07 29.8 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN56331.1 - 7.6e-07 29.1 5.9 7.6e-07 29.1 5.9 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN56331.1 - 0.00013 21.8 8.6 0.00021 21.2 8.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 RLN56331.1 - 0.0011 18.9 5.6 0.0025 17.8 5.7 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 RLN56331.1 - 0.0012 18.7 9.3 0.0019 18.0 9.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 RLN56331.1 - 0.038 13.6 7.9 0.063 12.9 7.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 RLN56331.1 - 0.044 13.9 5.4 0.1 12.7 5.4 1.6 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 RLN56331.1 - 0.26 11.5 11.9 0.18 12.0 9.4 2.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 RLN56331.1 - 0.94 9.7 7.3 4.3 7.6 7.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-rbx1 PF12678.7 RLN56332.1 - 6.9e-08 32.7 6.2 2.2e-07 31.1 6.2 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 RLN56332.1 - 2.1e-07 31.1 9.8 2.1e-07 31.1 9.8 2.7 2 2 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 RLN56332.1 - 2.1e-06 27.6 1.9 2.1e-06 27.6 1.9 2.4 2 2 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RLN56332.1 - 3.8e-06 26.7 2.6 3.8e-06 26.7 2.6 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN56332.1 - 7.4e-06 25.7 2.5 2.6e-05 24.0 2.5 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 RLN56332.1 - 1e-05 25.3 0.6 1e-05 25.3 0.6 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RLN56332.1 - 5.1e-05 23.2 0.3 0.00015 21.8 0.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 RLN56332.1 - 0.00019 21.3 1.0 0.00019 21.3 1.0 2.7 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RLN56332.1 - 0.00032 20.5 3.3 0.00032 20.5 3.3 2.4 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN56332.1 - 0.0015 18.2 0.8 0.0015 18.2 0.8 3.7 4 0 0 4 4 4 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 RLN56332.1 - 0.0021 17.6 0.8 0.0082 15.7 0.8 2.1 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 RLN56332.1 - 0.038 14.2 2.7 0.038 14.2 2.7 2.4 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 RLN56332.1 - 0.085 13.0 4.8 0.71 10.1 4.8 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain UPF0547 PF10571.9 RLN56332.1 - 0.51 10.5 3.5 6.9 6.9 0.3 3.2 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 MatE PF01554.18 RLN56333.1 - 3.6e-29 101.5 28.4 4.6e-24 84.9 10.8 2.6 2 1 0 2 2 2 2 MatE Pkinase PF00069.25 RLN56334.1 - 4.2e-44 150.9 0.5 7.6e-44 150.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN56334.1 - 8.2e-39 133.4 0.0 1.7e-38 132.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Alpha_kinase PF02816.18 RLN56334.1 - 2.6e-10 40.7 0.3 1.3e-09 38.5 0.0 2.1 2 0 0 2 2 2 1 Alpha-kinase family Kdo PF06293.14 RLN56334.1 - 1.5e-06 27.7 1.0 2.1e-06 27.3 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN56334.1 - 0.00049 19.0 0.0 0.00049 19.0 0.0 2.6 3 1 0 3 3 3 1 Fungal protein kinase APH PF01636.23 RLN56334.1 - 0.0017 18.3 1.7 0.023 14.6 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RLN56334.1 - 0.032 13.6 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like ABC1 PF03109.16 RLN56334.1 - 0.099 12.8 0.0 9 6.5 0.0 2.4 2 0 0 2 2 2 0 ABC1 family zf-Nse PF11789.8 RLN56335.1 - 0.0065 16.3 0.1 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Atg14 PF10186.9 RLN56335.1 - 0.19 10.8 12.9 0.33 10.0 12.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 C1_1 PF00130.22 RLN56335.1 - 0.25 11.3 2.7 0.57 10.1 2.7 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_16 PF13191.6 RLN56335.1 - 0.31 11.4 8.5 0.25 11.7 0.2 2.7 2 0 0 2 2 2 0 AAA ATPase domain DASH_Spc34 PF08657.10 RLN56335.1 - 0.42 10.4 8.7 0.77 9.5 8.7 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 Herpes_UL6 PF01763.16 RLN56335.1 - 0.71 8.3 5.2 1.3 7.5 5.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like NPF PF16601.5 RLN56335.1 - 0.81 10.1 5.4 0.34 11.3 2.6 1.7 2 0 0 2 2 2 0 Rabosyn-5 repeating NPF sequence-motif Na_H_Exchanger PF00999.21 RLN56336.1 - 2.2e-55 188.0 33.2 2.7e-55 187.7 33.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family 2-Hacid_dh_C PF02826.19 RLN56337.1 - 5.6e-43 146.4 0.0 8.5e-43 145.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 RLN56337.1 - 1.6e-05 25.1 0.0 2.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 RLN56337.1 - 0.009 16.6 0.1 0.031 14.9 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DUF1633 PF07794.11 RLN56337.1 - 0.078 11.2 0.0 0.086 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) 3HCDH_N PF02737.18 RLN56337.1 - 0.085 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 RLN56337.1 - 0.11 12.7 0.0 0.6 10.4 0.0 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 RLN56337.1 - 0.16 11.9 0.0 2.6 8.0 0.0 2.2 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Rossmann-like PF10727.9 RLN56337.1 - 0.17 11.8 0.1 0.72 9.7 0.1 2.0 1 1 1 2 2 2 0 Rossmann-like domain LRR_8 PF13855.6 RLN56338.1 - 5.9e-06 26.0 2.9 0.00049 19.8 0.4 2.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RLN56338.1 - 3.8e-05 24.0 0.4 0.012 16.0 0.2 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN56338.1 - 0.0027 17.2 0.2 0.0067 16.0 0.2 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 RLN56338.1 - 1.6 9.6 3.4 24 6.0 0.2 3.1 3 0 0 3 3 3 0 Leucine Rich Repeat Na_H_Exchanger PF00999.21 RLN56339.1 - 7.5e-57 192.9 35.0 9.2e-57 192.5 35.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family zf-RING_2 PF13639.6 RLN56340.1 - 1.8e-11 44.2 8.4 3.4e-11 43.3 8.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RLN56340.1 - 1.1e-08 35.2 8.2 2.7e-08 34.0 8.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 RLN56340.1 - 4.9e-08 32.7 4.9 1.4e-07 31.2 4.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN56340.1 - 2.5e-07 30.3 1.6 5.6e-07 29.2 1.6 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 RLN56340.1 - 1.3e-06 28.2 3.5 1.3e-06 28.2 3.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN56340.1 - 5.6e-06 26.1 5.7 9.2e-06 25.4 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN56340.1 - 1e-05 25.4 1.7 2.2e-05 24.4 1.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 RLN56340.1 - 0.001 19.1 3.6 0.0022 18.0 3.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 RLN56340.1 - 0.0015 18.4 3.4 0.0034 17.2 3.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 RINGv PF12906.7 RLN56340.1 - 0.0076 16.4 2.4 0.024 14.7 2.4 1.9 1 1 0 1 1 1 1 RING-variant domain zf-RING_5 PF14634.6 RLN56340.1 - 0.01 15.8 5.7 0.02 14.9 5.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_10 PF16685.5 RLN56340.1 - 0.016 15.4 3.0 0.029 14.5 3.0 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 RLN56340.1 - 0.055 13.3 5.0 0.046 13.5 3.5 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 RLN56340.1 - 0.078 13.2 5.1 0.18 12.0 5.1 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain Baculo_IE-1 PF05290.11 RLN56340.1 - 0.18 11.8 1.7 0.39 10.6 1.7 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.6 RLN56340.1 - 0.18 12.0 10.9 0.058 13.6 6.5 2.4 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 RLN56340.1 - 1.7 9.0 7.0 3.5 8.0 6.8 1.7 1 1 0 1 1 1 0 RING-like domain Nckap1 PF09735.9 RLN56341.1 - 1.9e-39 135.5 0.0 1.8e-29 102.5 0.0 3.6 2 2 0 3 3 3 3 Membrane-associated apoptosis protein Cu-oxidase_2 PF07731.14 RLN56342.1 - 1.3e-36 125.4 7.5 5e-30 104.0 2.2 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN56342.1 - 2.8e-31 108.0 3.7 2.2e-30 105.1 0.1 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 RLN56342.1 - 1.2e-25 90.5 0.0 3.8e-25 88.9 0.0 1.9 1 0 0 1 1 1 1 Multicopper oxidase EF-hand_6 PF13405.6 RLN56343.1 - 5.9e-21 72.6 5.5 0.00058 19.6 0.0 9.5 9 0 0 9 9 9 4 EF-hand domain EF-hand_1 PF00036.32 RLN56343.1 - 1.8e-19 67.8 2.3 0.0017 17.7 0.0 9.2 11 0 0 11 11 11 3 EF hand EF-hand_7 PF13499.6 RLN56343.1 - 8.3e-19 67.8 3.1 0.00098 19.5 0.0 7.3 7 1 0 7 7 7 3 EF-hand domain pair EF-hand_8 PF13833.6 RLN56343.1 - 2.7e-12 46.3 2.5 0.016 15.0 0.2 6.1 7 0 0 7 7 7 3 EF-hand domain pair EF-hand_5 PF13202.6 RLN56343.1 - 4.8e-11 41.6 1.9 0.0003 20.1 0.0 6.4 7 0 0 7 7 7 2 EF hand Vps35 PF03635.17 RLN56379.1 - 7.7e-218 725.6 0.3 8.8e-218 725.4 0.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 NTP_transf_3 PF12804.7 RLN56379.1 - 3 8.2 7.4 0.29 11.5 0.2 2.9 3 1 0 3 3 3 0 MobA-like NTP transferase domain DUF3584 PF12128.8 RLN56380.1 - 0.00069 17.3 5.7 0.00082 17.0 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 RLN56380.1 - 0.0042 17.3 4.9 0.24 11.6 0.1 2.2 2 0 0 2 2 2 2 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 RLN56380.1 - 0.097 12.7 6.5 0.05 13.6 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HIP1_clath_bdg PF16515.5 RLN56380.1 - 0.1 13.2 14.5 1.3 9.7 2.0 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 KxDL PF10241.9 RLN56380.1 - 0.2 12.0 6.5 1.3 9.4 1.3 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein Fez1 PF06818.15 RLN56380.1 - 0.21 12.0 10.7 0.28 11.6 10.7 1.2 1 0 0 1 1 1 0 Fez1 DUF4201 PF13870.6 RLN56380.1 - 0.28 10.9 10.4 0.21 11.3 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) HMMR_C PF15908.5 RLN56380.1 - 0.29 11.4 4.6 1.5 9.1 1.0 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal UPF0242 PF06785.11 RLN56380.1 - 0.41 10.7 9.2 0.73 9.9 9.2 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus COG5 PF10392.9 RLN56380.1 - 0.82 9.8 8.0 3.3 7.9 1.4 2.2 2 0 0 2 2 2 0 Golgi transport complex subunit 5 HAUS6_N PF14661.6 RLN56380.1 - 2.1 7.9 8.3 1.3 8.6 6.0 1.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Exonuc_VII_L PF02601.15 RLN56380.1 - 4.4 6.8 7.8 5.6 6.4 7.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4131 PF13567.6 RLN56381.1 - 0.033 13.8 0.1 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Orthoreo_P10 PF07204.11 RLN56381.1 - 0.082 12.9 0.9 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 PRMT5_TIM PF17285.2 RLN56382.1 - 2e-67 227.1 0.0 3.4e-67 226.4 0.0 1.3 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 RLN56382.1 - 3.7e-58 196.2 0.0 5.7e-58 195.6 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 RLN56382.1 - 3.7e-54 183.3 0.0 6.1e-54 182.6 0.0 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain LacAB_rpiB PF02502.18 RLN56382.1 - 0.065 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribose/Galactose Isomerase Methyltransf_31 PF13847.6 RLN56382.1 - 0.083 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_M48_N PF16491.5 RLN56383.1 - 5.3e-64 215.5 0.9 7.8e-64 214.9 0.9 1.2 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices GBP PF02263.19 RLN56384.1 - 1e-25 90.5 0.0 3.7e-25 88.7 0.0 1.9 2 1 0 2 2 2 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 RLN56384.1 - 0.15 11.5 48.3 31 3.9 42.5 3.3 1 1 1 2 2 2 0 Guanylate-binding protein, C-terminal domain Ubiq-Cytc-red_N PF09165.10 RLN56385.1 - 0.21 12.5 2.5 0.31 12.0 0.8 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal PA PF02225.22 RLN56386.1 - 1.6e-15 56.9 0.5 3.8e-07 30.0 0.1 2.4 2 0 0 2 2 2 2 PA domain Aa_trans PF01490.18 RLN56410.1 - 2.6e-09 36.3 13.2 2.3e-07 29.9 2.0 2.5 3 0 0 3 3 3 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 RLN56410.1 - 0.0061 15.6 17.9 0.0061 15.6 1.2 3.1 2 1 0 3 3 3 2 Tryptophan/tyrosine permease family Aconitase_C PF00694.19 RLN56411.1 - 2.6e-23 82.8 0.0 3.5e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF4160 PF13711.6 RLN56412.1 - 0.069 13.5 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) Peptidase_M13_N PF05649.13 RLN56412.1 - 0.23 11.1 0.1 0.9 9.1 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M13 Pkinase PF00069.25 RLN56413.1 - 1.1e-51 175.7 0.2 1.7e-46 158.8 0.1 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN56413.1 - 3.3e-23 82.3 0.1 3.9e-23 82.0 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN56413.1 - 1e-07 31.1 0.1 5.5e-06 25.4 0.0 2.0 2 0 0 2 2 2 2 Fungal protein kinase Kdo PF06293.14 RLN56413.1 - 4.7e-06 26.1 0.1 6.9e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN56413.1 - 0.0029 17.6 0.0 1 9.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 RLN56413.1 - 0.0045 16.6 0.1 0.0068 16.0 0.1 1.2 1 0 0 1 1 1 1 RIO1 family IQ PF00612.27 RLN56421.1 - 5.1e-30 100.4 84.1 0.00098 18.7 1.9 12.8 12 0 0 12 12 12 12 IQ calmodulin-binding motif WW PF00397.26 RLN56421.1 - 2.6e-11 43.4 13.1 1.3e-06 28.4 1.5 2.5 2 0 0 2 2 2 2 WW domain YL1 PF05764.13 RLN56424.1 - 0.027 14.6 12.6 0.04 14.0 12.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Pro-rich PF15240.6 RLN56424.1 - 0.036 14.3 26.9 0.049 13.9 26.9 1.1 1 0 0 1 1 1 0 Proline-rich CDC45 PF02724.14 RLN56424.1 - 1.9 6.7 8.9 2.1 6.6 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.16 RLN56424.1 - 2.6 7.5 7.2 3.3 7.2 7.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Presenilin PF01080.17 RLN56424.1 - 3.5 6.3 8.8 4.9 5.8 8.8 1.3 1 0 0 1 1 1 0 Presenilin TFIIF_alpha PF05793.12 RLN56424.1 - 3.6 6.1 16.7 4.8 5.7 16.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TRAM_LAG1_CLN8 PF03798.16 RLN56438.1 - 9.1e-30 103.9 13.5 1.3e-29 103.3 13.5 1.3 1 0 0 1 1 1 1 TLC domain DEK_C PF08766.11 RLN56439.1 - 5.9e-06 26.1 0.1 1.2e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 DEK C terminal domain CHZ PF09649.10 RLN56439.1 - 7.1e-05 22.2 0.1 0.00025 20.4 0.1 2.0 1 0 0 1 1 1 1 Histone chaperone domain CHZ BUD22 PF09073.10 RLN56439.1 - 0.002 17.6 11.6 0.002 17.6 11.6 2.1 2 0 0 2 2 2 2 BUD22 Shugoshin_C PF07557.11 RLN56439.1 - 0.019 14.8 0.8 0.019 14.8 0.8 2.5 3 0 0 3 3 3 0 Shugoshin C terminus EcKinase PF02958.20 RLN56440.1 - 5.8e-19 68.5 0.0 5.6e-18 65.3 0.0 2.1 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 RLN56440.1 - 7e-12 44.9 0.0 3.5e-11 42.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 RLN56440.1 - 1.1e-11 45.2 0.3 1.7e-11 44.5 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-BED PF02892.15 RLN56451.1 - 0.0016 18.4 0.4 0.0064 16.5 0.2 2.0 2 0 0 2 2 2 1 BED zinc finger Tom37 PF10568.9 RLN56451.1 - 0.021 15.1 0.0 0.18 12.2 0.0 2.2 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein MULE PF10551.9 RLN56452.1 - 3.7e-08 33.7 0.0 6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 MULE transposase domain Myosin_head PF00063.21 RLN56465.1 - 1.2e-230 767.3 0.1 1.5e-230 767.1 0.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 RLN56465.1 - 0.018 14.9 0.2 0.036 13.9 0.2 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 RLN56465.1 - 0.021 15.2 0.2 0.088 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 RLN56465.1 - 0.027 14.6 1.1 0.055 13.5 0.2 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 RLN56465.1 - 0.05 13.9 0.0 0.21 11.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 RLN56465.1 - 0.11 12.4 0.0 8.6 6.3 0.0 2.7 2 0 0 2 2 2 0 Microtubule binding AAA_18 PF13238.6 RLN56465.1 - 0.12 13.0 0.0 0.52 10.9 0.0 2.2 1 0 0 1 1 1 0 AAA domain Syndecan PF01034.20 RLN56466.1 - 0.089 12.7 0.2 6.5 6.7 0.3 2.2 2 0 0 2 2 2 0 Syndecan domain Ferric_reduct PF01794.19 RLN56467.1 - 4.2e-15 56.0 5.8 4.2e-15 56.0 5.8 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 RLN56467.1 - 1.1e-09 38.3 0.0 2.2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.24 RLN56467.1 - 0.00053 20.3 0.0 0.00091 19.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain CrgA PF06781.12 RLN56467.1 - 0.11 12.5 4.1 4.1 7.5 0.1 2.9 3 0 0 3 3 3 0 Cell division protein CrgA Dimer_Tnp_hAT PF05699.14 RLN56492.1 - 4.6e-10 39.1 0.1 1.1e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 RLN56492.1 - 4.3e-07 29.8 0.1 4.3e-07 29.8 0.1 1.9 2 0 0 2 2 2 1 BED zinc finger TetR_C_33 PF13305.6 RLN56492.1 - 0.031 15.0 0.9 0.36 11.6 0.6 2.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF4726 PF15855.5 RLN56492.1 - 0.12 12.6 3.7 27 5.1 0.0 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4726) RWP-RK PF02042.15 RLN56493.1 - 1.1e-13 51.0 0.0 2.4e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 RWP-RK domain Sigma70_r4_2 PF08281.12 RLN56493.1 - 0.0012 18.5 0.1 0.0055 16.3 0.1 1.9 1 1 1 2 2 2 2 Sigma-70, region 4 HTH_50 PF18024.1 RLN56493.1 - 0.017 14.7 0.1 0.038 13.6 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_6 PF01418.17 RLN56493.1 - 0.018 15.0 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family TnsD PF15978.5 RLN56493.1 - 0.055 12.5 0.2 0.087 11.8 0.2 1.3 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_38 PF13936.6 RLN56493.1 - 0.078 12.8 1.0 0.12 12.1 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 RLN56493.1 - 0.12 12.6 0.2 11 6.3 0.1 2.9 1 1 2 3 3 3 0 Helix-turn-helix domain Peptidase_C48 PF02902.19 RLN56495.1 - 2.7e-10 40.5 0.6 4.8e-10 39.6 0.6 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 RLN56495.1 - 0.07 11.8 0.1 0.45 9.2 0.0 1.9 1 1 1 2 2 2 0 Vaccinia virus I7 processing peptidase zf-RING_2 PF13639.6 RLN56506.1 - 8.9e-07 29.1 8.8 8.9e-07 29.1 8.8 2.6 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 RLN56506.1 - 2.1e-06 27.9 6.5 5.2e-06 26.6 6.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RLN56506.1 - 2.3e-05 24.3 9.7 2.3e-05 24.3 9.7 2.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 RLN56506.1 - 0.0012 18.9 2.8 0.0026 17.8 2.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 RLN56506.1 - 0.0027 17.5 11.1 0.0027 17.5 11.1 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN56506.1 - 0.0042 16.9 11.3 0.0042 16.9 11.3 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Dmrt1 PF12374.8 RLN56506.1 - 0.0062 16.9 0.2 0.45 11.0 0.1 3.3 2 0 0 2 2 2 1 Double-sex mab3 related transcription factor 1 Prok-RING_4 PF14447.6 RLN56506.1 - 0.0065 16.3 7.8 0.035 14.0 8.0 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 RLN56506.1 - 0.0067 16.2 3.4 0.013 15.2 3.4 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 RLN56506.1 - 0.013 15.5 7.4 0.013 15.5 7.4 2.3 3 0 0 3 3 3 0 RING-type zinc-finger zinc_ribbon_15 PF17032.5 RLN56506.1 - 0.063 14.0 7.7 4.1 8.2 0.0 3.5 3 0 0 3 3 3 0 zinc-ribbon family Zn_ribbon_17 PF17120.5 RLN56506.1 - 0.83 9.3 11.9 0.088 12.4 7.1 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Ank_4 PF13637.6 RLN56507.1 - 2e-20 72.9 1.1 1.1e-06 29.0 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN56507.1 - 1.2e-17 63.8 2.7 2.5e-11 43.6 0.5 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN56507.1 - 9.5e-16 58.2 1.4 1.4e-11 44.8 0.4 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN56507.1 - 1.7e-09 37.1 0.6 0.0044 17.4 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 RLN56507.1 - 2.3e-06 27.8 0.4 0.034 14.6 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat ATG11 PF10377.9 RLN56522.1 - 4e-20 72.2 0.9 3.2e-19 69.2 0.0 2.8 3 1 0 4 4 4 1 Autophagy-related protein 11 PI3K_P85_iSH2 PF16454.5 RLN56522.1 - 0.061 12.9 16.4 0.15 11.7 0.9 3.8 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain NBP1 PF08537.10 RLN56522.1 - 0.11 11.9 0.1 0.11 11.9 0.1 2.4 3 0 0 3 3 3 0 Fungal Nap binding protein NBP1 PPE PF00823.19 RLN56522.1 - 2.2 8.4 5.6 5.4 7.1 0.6 2.6 2 0 0 2 2 2 0 PPE family DUF4736 PF15883.5 RLN56522.1 - 2.6 7.7 5.5 23 4.6 1.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) Sec8_exocyst PF04048.14 RLN56522.1 - 5.4 6.9 13.5 0.43 10.4 0.4 3.8 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain Tnp_22_trimer PF17489.2 RLN56522.1 - 7.4 6.6 6.5 0.64 10.0 0.2 2.3 2 0 0 2 2 2 0 L1 transposable element trimerization domain Atg14 PF10186.9 RLN56522.1 - 7.6 5.5 15.5 4.3 6.3 0.1 3.3 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Na_H_Exchanger PF00999.21 RLN56523.1 - 7.9e-42 143.4 22.4 9.4e-42 143.2 22.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family BRI3BP PF14965.6 RLN56523.1 - 0.016 14.7 0.4 0.047 13.2 0.4 1.8 1 0 0 1 1 1 0 Negative regulator of p53/TP53 SH PF01445.17 RLN56523.1 - 3.7 7.6 6.4 0.94 9.5 0.4 2.7 3 0 0 3 3 3 0 Viral small hydrophobic protein BTB PF00651.31 RLN56524.1 - 1.6e-10 41.2 0.6 6.9e-10 39.1 0.6 2.2 1 1 0 1 1 1 1 BTB/POZ domain Cnd1 PF12717.7 RLN56524.1 - 3.7e-06 27.1 0.6 5.7e-05 23.2 0.1 2.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 RLN56524.1 - 0.00013 21.9 0.3 0.056 13.5 0.0 4.0 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN56524.1 - 0.00049 20.1 0.9 4.9 7.7 0.0 4.2 3 0 0 3 3 3 1 HEAT repeat Epimerase PF01370.21 RLN56524.1 - 0.001 18.6 0.2 0.0071 15.8 0.1 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family HEAT_2 PF13646.6 RLN56524.1 - 0.0087 16.4 0.4 0.11 12.9 0.0 2.7 2 1 1 3 3 3 1 HEAT repeats GDP_Man_Dehyd PF16363.5 RLN56524.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Arm_2 PF04826.13 RLN56524.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Armadillo-like Na_H_Exchanger PF00999.21 RLN56525.1 - 1e-05 24.5 0.8 1.2e-05 24.3 0.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Bap31 PF05529.12 RLN56526.1 - 4.7e-08 33.0 1.8 1.2e-07 31.7 1.8 1.7 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region UPF0242 PF06785.11 RLN56526.1 - 0.0004 20.5 17.5 0.00044 20.4 3.1 2.0 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Bap31_Bap29_C PF18035.1 RLN56526.1 - 0.00096 19.1 27.9 0.12 12.4 4.6 4.8 2 2 1 3 3 3 2 Bap31/Bap29 cytoplasmic coiled-coil domain DivIC PF04977.15 RLN56526.1 - 0.012 15.4 21.0 0.012 15.4 3.3 3.3 2 1 0 3 3 3 0 Septum formation initiator FBPase PF00316.20 RLN56526.1 - 0.038 13.5 0.5 0.052 13.0 0.5 1.3 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain DUF4600 PF15372.6 RLN56526.1 - 0.15 12.5 14.1 0.37 11.2 9.2 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4600) Csm1_N PF18504.1 RLN56526.1 - 0.16 12.3 17.8 0.095 13.1 1.2 3.3 1 1 2 3 3 3 0 Csm1 N-terminal domain YabA PF06156.13 RLN56526.1 - 0.4 11.3 12.7 0.11 13.2 1.1 3.0 1 1 1 2 2 2 0 Initiation control protein YabA DUF948 PF06103.11 RLN56526.1 - 0.49 10.7 7.9 0.46 10.8 0.5 3.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Occludin_ELL PF07303.13 RLN56526.1 - 0.56 11.0 10.2 0.94 10.2 4.1 2.4 1 1 1 2 2 2 0 Occludin homology domain GAS PF13851.6 RLN56526.1 - 0.73 9.2 21.4 1.4 8.2 14.5 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.9 RLN56526.1 - 2.5 8.5 14.4 3.4 8.0 7.4 2.5 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4559 PF15112.6 RLN56526.1 - 3.6 7.2 11.3 0.15 11.7 3.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) FAD-SLDH PF12318.8 RLN56526.1 - 5 7.2 10.3 0.38 10.8 0.3 2.6 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase HALZ PF02183.18 RLN56526.1 - 5.2 7.4 15.5 0.7 10.2 1.3 3.7 3 1 0 3 3 3 0 Homeobox associated leucine zipper DUF16 PF01519.16 RLN56526.1 - 8.3 7.0 13.9 1.6e+02 2.8 13.9 2.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF2058 PF09831.9 RLN56526.1 - 9.6 6.3 19.0 0.32 11.2 11.7 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) XPG_I PF00867.18 RLN56576.1 - 2.8e-07 30.8 0.0 7.1e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 XPG I-region DEAD PF00270.29 RLN56576.1 - 2.9e-07 30.4 0.8 7.4e-07 29.1 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.6 RLN56576.1 - 3.3e-05 23.8 0.1 7.8e-05 22.6 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RLN56576.1 - 0.00015 22.1 0.1 0.0043 17.3 0.0 3.1 3 1 0 3 3 3 1 AAA domain NACHT PF05729.12 RLN56576.1 - 0.004 17.1 0.0 0.029 14.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 RLN56576.1 - 0.011 16.2 0.0 0.23 11.8 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain TniB PF05621.11 RLN56576.1 - 0.012 15.0 0.0 7.6 5.9 0.0 2.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_30 PF13604.6 RLN56576.1 - 0.084 12.6 0.4 1.7 8.3 0.0 2.8 4 0 0 4 4 4 0 AAA domain Viral_helicase1 PF01443.18 RLN56576.1 - 0.12 12.1 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase XPG_N PF00752.17 RLN56576.1 - 0.14 12.6 0.0 0.79 10.2 0.0 2.2 2 0 0 2 2 2 0 XPG N-terminal domain CSD2 PF17876.1 RLN56576.1 - 0.14 12.3 0.0 24 5.2 0.0 2.8 2 0 0 2 2 2 0 Cold shock domain zf-RING_2 PF13639.6 RLN56577.1 - 1.5e-07 31.7 9.4 2.8e-07 30.8 9.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 RLN56577.1 - 9e-06 25.3 5.0 2e-05 24.2 0.8 2.4 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 RLN56577.1 - 2.9e-05 23.8 7.2 2.9e-05 23.8 7.2 1.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 RLN56577.1 - 4.1e-05 23.4 6.5 8.7e-05 22.3 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN56577.1 - 0.00012 21.9 6.3 0.00012 21.9 6.3 1.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 RLN56577.1 - 0.0025 17.6 4.2 0.0053 16.5 4.2 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 RLN56577.1 - 0.0062 16.4 10.8 0.024 14.5 11.1 1.9 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN56577.1 - 0.013 15.3 8.3 0.046 13.6 8.3 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN56577.1 - 0.014 15.4 6.2 0.032 14.2 6.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.29 RLN56577.1 - 0.088 12.7 6.6 0.15 11.9 6.6 1.4 1 0 0 1 1 1 0 PHD-finger zf-rbx1 PF12678.7 RLN56577.1 - 0.87 9.9 8.9 1.8 8.9 8.9 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 RLN56577.1 - 1 9.6 8.8 0.67 10.2 3.7 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 RLN56577.1 - 2.4 8.5 10.9 0.54 10.6 7.4 1.8 2 0 0 2 2 2 0 RING-like domain Amidohydro_1 PF01979.20 RLN56578.1 - 1.8e-54 185.4 0.0 2.1e-54 185.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 RLN56578.1 - 1.8e-10 40.9 0.8 2.5e-07 30.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family MtN3_slv PF03083.16 RLN56587.1 - 3e-25 88.1 9.2 1.9e-15 56.6 3.3 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Prominin PF05478.11 RLN56587.1 - 0.027 12.4 0.6 0.037 12.0 0.6 1.1 1 0 0 1 1 1 0 Prominin PQ-loop PF04193.14 RLN56587.1 - 0.18 11.6 5.6 0.19 11.5 0.2 3.4 4 0 0 4 4 4 0 PQ loop repeat MerC PF03203.14 RLN56587.1 - 0.4 11.2 11.2 1.6 9.2 11.2 2.0 1 1 1 2 2 2 0 MerC mercury resistance protein MtN3_slv PF03083.16 RLN56588.1 - 1.5e-26 92.2 14.9 5.5e-17 61.6 4.7 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange MerC PF03203.14 RLN56588.1 - 0.63 10.5 14.8 0.77 10.2 11.1 2.7 1 1 1 2 2 2 0 MerC mercury resistance protein MtN3_slv PF03083.16 RLN56589.1 - 4.7e-26 90.6 14.3 1.9e-15 56.7 4.4 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Pox_A14 PF05767.12 RLN56589.1 - 0.048 13.8 1.0 0.16 12.2 1.0 1.9 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF4131 PF13567.6 RLN56589.1 - 0.64 9.7 6.4 0.54 9.9 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Oxidored_FMN PF00724.20 RLN56590.1 - 3.6e-80 269.8 0.0 4.4e-80 269.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MtN3_slv PF03083.16 RLN56591.1 - 1.7e-25 88.8 6.6 1.3e-16 60.4 0.6 2.8 2 1 1 3 3 3 2 Sugar efflux transporter for intercellular exchange Ank_2 PF12796.7 RLN56592.1 - 5.2e-31 107.1 0.9 1.2e-06 29.0 0.1 6.7 4 2 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN56592.1 - 2.4e-28 98.1 7.1 3.8e-06 27.3 0.1 9.3 8 1 1 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN56592.1 - 3.6e-19 68.6 11.4 0.028 14.7 0.0 12.0 7 3 5 12 12 12 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN56592.1 - 1.4e-14 52.7 1.0 1.7 9.5 0.0 11.5 13 0 0 13 13 13 1 Ankyrin repeat Ank PF00023.30 RLN56592.1 - 0.0032 17.8 2.6 15 6.3 0.0 6.2 6 2 0 6 6 6 1 Ankyrin repeat Metallophos PF00149.28 RLN56593.1 - 2.6e-11 44.4 1.0 4.2e-11 43.7 1.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RLN56593.1 - 0.00094 19.4 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MtN3_slv PF03083.16 RLN56594.1 - 1.2e-15 57.3 6.9 1.6e-15 56.9 1.0 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange MASE3 PF17159.4 RLN56594.1 - 0.023 14.3 6.2 0.14 11.8 2.7 2.0 1 1 1 2 2 2 0 Membrane-associated sensor domain MtN3_slv PF03083.16 RLN56595.1 - 1.3e-06 28.4 1.8 1.5e-06 28.1 1.8 1.1 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange PsbN PF02468.15 RLN56595.1 - 0.26 11.2 1.8 0.36 10.7 0.1 1.9 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) Mg_trans_NIPA PF05653.14 RLN56598.1 - 1.3e-20 73.7 1.1 1.7e-20 73.4 1.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA UbiA PF01040.18 RLN56598.1 - 9.5e-05 21.8 1.3 0.00013 21.4 1.3 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3098 PF11297.8 RLN56598.1 - 0.048 13.3 0.1 0.12 12.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) DREPP PF05558.12 RLN56598.1 - 0.24 11.3 5.9 0.38 10.6 5.9 1.2 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide EamA PF00892.20 RLN56598.1 - 0.7 10.1 11.4 0.29 11.3 8.1 2.1 2 1 0 2 2 2 0 EamA-like transporter family DUF3730 PF12530.8 RLN56599.1 - 1.3e-19 70.7 0.9 1.3e-19 70.7 0.9 4.3 4 0 0 4 4 4 1 Protein of unknown function (DUF3730) HEAT PF02985.22 RLN56599.1 - 0.00087 19.4 9.1 1.1 9.7 0.1 6.1 5 0 0 5 5 5 2 HEAT repeat AraC_N PF06719.13 RLN56599.1 - 0.28 10.8 3.1 0.86 9.2 0.0 3.2 3 0 0 3 3 3 0 AraC-type transcriptional regulator N-terminus cwf21 PF08312.12 RLN56599.1 - 2.7 8.2 4.5 0.53 10.5 0.5 1.9 2 0 0 2 2 2 0 cwf21 domain EBP50_C PF09007.11 RLN56616.1 - 2.5 9.1 8.1 2.4 9.2 1.9 2.5 2 1 0 2 2 2 0 EBP50, C-terminal DUF848 PF05852.11 RLN56617.1 - 0.00048 20.3 5.0 0.078 13.1 0.0 3.7 3 1 0 3 3 3 2 Gammaherpesvirus protein of unknown function (DUF848) PapD_N PF00345.20 RLN56617.1 - 0.05 13.5 0.9 0.11 12.5 0.1 1.9 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain bZIP_1 PF00170.21 RLN56617.1 - 0.05 13.7 14.6 0.34 11.1 2.0 3.8 3 0 0 3 3 3 0 bZIP transcription factor OGG_N PF07934.12 RLN56617.1 - 0.096 12.8 0.8 0.33 11.1 0.8 1.9 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain Gon7 PF08738.10 RLN56617.1 - 0.25 11.4 8.0 2.5 8.2 1.7 3.3 3 1 1 4 4 4 0 Gon7 family Elicitin PF00964.17 RLN56618.1 - 6e-21 74.4 2.4 6e-21 74.4 2.4 1.5 1 1 0 1 1 1 1 Elicitin IL13 PF03487.13 RLN56618.1 - 0.0034 17.2 0.7 0.0037 17.0 0.4 1.3 1 1 0 1 1 1 1 Interleukin-13 Lyase_8_C PF02884.17 RLN56619.1 - 0.00041 20.8 0.1 1.3 9.5 0.0 2.8 2 0 0 2 2 2 2 Polysaccharide lyase family 8, C-terminal beta-sandwich domain ABC_tran_CTD PF16326.5 RLN56619.1 - 0.4 11.0 10.4 0.64 10.3 1.2 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain GreA_GreB_N PF03449.15 RLN56619.1 - 2.4 8.4 8.1 4.6 7.5 0.3 2.8 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Arm PF00514.23 RLN56628.1 - 2.7e-64 211.4 3.2 2e-12 46.7 0.1 6.1 6 0 0 6 6 6 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN56628.1 - 8.3e-18 64.5 1.4 5.2e-07 30.0 0.1 5.0 3 3 1 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 RLN56628.1 - 2.7e-14 53.3 0.0 4.5e-06 27.0 0.0 3.9 2 2 1 3 3 3 2 HEAT repeats HEAT PF02985.22 RLN56628.1 - 3.5e-12 45.5 0.4 4.8e-05 23.3 0.0 5.5 6 0 0 6 6 6 2 HEAT repeat IBB PF01749.20 RLN56628.1 - 2.4e-11 43.9 1.7 5.4e-11 42.8 1.7 1.6 1 0 0 1 1 1 1 Importin beta binding domain Arm_2 PF04826.13 RLN56628.1 - 0.00018 21.1 0.0 0.37 10.2 0.0 2.3 1 1 1 2 2 2 2 Armadillo-like V-ATPase_H_C PF11698.8 RLN56628.1 - 0.00029 20.9 0.0 0.014 15.5 0.0 2.6 2 1 0 2 2 2 1 V-ATPase subunit H HEAT_PBS PF03130.16 RLN56628.1 - 0.00056 20.3 0.2 0.73 10.7 0.0 4.2 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 RLN56628.1 - 0.0016 18.5 0.1 0.094 12.8 0.0 3.5 3 3 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Adaptin_N PF01602.20 RLN56628.1 - 0.0077 14.8 0.0 0.011 14.3 0.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Xpo1 PF08389.12 RLN56628.1 - 0.021 14.9 0.1 1.2 9.2 0.0 3.0 4 0 0 4 4 4 0 Exportin 1-like protein RICTOR_V PF14668.6 RLN56628.1 - 0.032 14.5 0.6 23 5.3 0.1 3.7 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 MIT PF04212.18 RLN56629.1 - 7.8e-21 73.9 2.4 4.1e-13 49.2 0.0 3.0 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 RLN56629.1 - 0.025 14.7 2.6 0.056 13.6 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN56629.1 - 0.25 11.3 0.3 0.25 11.3 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat HSP33 PF01430.19 RLN56630.1 - 3.4e-35 121.8 0.0 5.9e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 Hsp33 protein DUF3342 PF11822.8 RLN56630.1 - 1.7e-28 98.7 2.3 4.2e-28 97.4 2.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) BTB PF00651.31 RLN56630.1 - 1.4e-05 25.3 0.3 3.2e-05 24.1 0.3 1.5 1 0 0 1 1 1 1 BTB/POZ domain Nmad3 PF18754.1 RLN56630.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 AAA PF00004.29 RLN56631.1 - 5.8e-20 72.1 0.0 6.4e-20 71.9 0.0 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 RLN56631.1 - 0.13 12.4 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Ank_2 PF12796.7 RLN56632.1 - 1.2e-18 67.5 14.4 1.2e-07 32.2 0.7 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN56632.1 - 4.4e-15 55.8 10.5 1.1e-05 25.9 0.2 4.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN56632.1 - 7.5e-13 48.4 12.4 0.054 13.8 0.2 6.0 1 1 5 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN56632.1 - 1.1e-08 34.7 6.6 3 8.7 0.0 6.4 4 2 2 6 6 6 2 Ankyrin repeat Glyco_hydro_12 PF01670.16 RLN56632.1 - 3.5e-06 27.2 0.1 6.9e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 DUF5049 PF16468.5 RLN56632.1 - 0.00066 19.5 0.7 10 6.1 0.0 3.9 1 1 3 4 4 4 2 Domain of unknown function (DUF5049) Ank PF00023.30 RLN56632.1 - 0.0015 18.9 10.9 27 5.4 0.0 5.9 2 2 3 5 5 5 0 Ankyrin repeat YmaF PF12788.7 RLN56632.1 - 0.18 12.3 2.1 7.1 7.2 0.3 2.5 1 1 1 2 2 2 0 YmaF family PH PF00169.29 RLN56633.1 - 2.7e-09 37.5 0.1 7.4e-09 36.1 0.0 1.8 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 RLN56633.1 - 0.00042 20.5 0.6 0.004 17.4 0.6 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.7 RLN56633.1 - 0.0019 18.3 0.0 0.0035 17.5 0.0 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH_11 PF15413.6 RLN56633.1 - 0.0051 17.2 0.1 0.011 16.2 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain zf-C6H2 PF15801.5 RLN56633.1 - 0.011 16.0 8.2 0.011 16.0 8.2 2.8 3 0 0 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding CBS PF00571.28 RLN56710.1 - 3.4e-14 53.0 0.0 1.4e-07 31.8 0.0 2.7 2 0 0 2 2 2 2 CBS domain DUF4272 PF14094.6 RLN56710.1 - 0.02 14.1 0.6 4.9 6.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4272) ALC PF17527.2 RLN56710.1 - 0.12 12.0 0.0 0.35 10.5 0.0 1.7 2 0 0 2 2 2 0 Phage ALC protein XRCC1_N PF01834.16 RLN56711.1 - 0.0057 16.7 0.0 0.0088 16.1 0.0 1.2 1 0 0 1 1 1 1 XRCC1 N terminal domain F5_F8_type_C PF00754.25 RLN56711.1 - 0.072 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 F5/8 type C domain RdRP PF05183.12 RLN56712.1 - 1.5e-143 479.5 0.0 2.2e-143 479.0 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Helicase_C PF00271.31 RLN56712.1 - 2.1e-16 60.2 0.1 1e-15 58.1 0.1 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN56712.1 - 7e-12 45.7 0.0 1.7e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RLN56712.1 - 2.7e-10 40.3 0.0 6.6e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase NTP_transf_2 PF01909.23 RLN56712.1 - 0.011 15.9 0.1 0.11 12.8 0.0 2.7 2 0 0 2 2 2 0 Nucleotidyltransferase domain Polbeta PF18765.1 RLN56712.1 - 0.038 14.1 0.0 0.17 12.0 0.0 2.1 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Yippee-Mis18 PF03226.14 RLN56713.1 - 0.027 14.7 4.3 0.088 13.0 4.3 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 RLN56713.1 - 0.69 10.2 4.9 2.5 8.4 2.5 2.4 1 1 1 2 2 2 0 C-terminal domain of RIG-I OrfB_Zn_ribbon PF07282.11 RLN56714.1 - 6.4e-09 35.6 1.1 1.9e-08 34.1 1.1 1.8 1 1 0 1 1 1 1 Putative transposase DNA-binding domain CDC27 PF09507.10 RLN56726.1 - 1.9 7.8 30.8 2.7 7.3 30.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HECT PF00632.25 RLN56727.1 - 4.8e-91 305.4 0.0 8.2e-91 304.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SYCE1 PF15233.6 RLN56727.1 - 0.45 10.6 2.2 0.85 9.7 2.2 1.3 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 Pkinase_Tyr PF07714.17 RLN56728.1 - 1.9e-51 174.8 0.0 8.3e-40 136.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN56728.1 - 4.7e-47 160.6 0.0 1.1e-34 120.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Arm PF00514.23 RLN56728.1 - 3e-29 100.1 28.1 0.0028 17.6 0.0 15.2 16 2 2 18 18 18 8 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN56728.1 - 1.6e-08 34.1 23.4 4.4 7.8 0.0 11.4 12 0 0 12 12 12 3 HEAT repeat HEAT_2 PF13646.6 RLN56728.1 - 6.9e-05 23.2 42.0 0.1 13.0 0.6 7.7 4 2 3 8 8 8 4 HEAT repeats HEAT_EZ PF13513.6 RLN56728.1 - 0.00036 21.0 46.5 0.097 13.2 1.0 9.6 7 4 4 11 11 11 5 HEAT-like repeat Kinase-like PF14531.6 RLN56728.1 - 0.029 13.7 0.0 0.71 9.1 0.0 2.3 2 0 0 2 2 2 0 Kinase-like DUF3303 PF11746.8 RLN56728.1 - 0.038 14.3 0.0 39 4.6 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF3303) KH_2 PF07650.17 RLN56755.1 - 1.6e-05 24.7 0.1 2.4e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 KH domain Sulfate_transp PF00916.20 RLN56756.1 - 1e-25 90.3 2.5 1.6e-24 86.4 2.5 2.4 1 1 0 1 1 1 1 Sulfate permease family DUF35_N PF12172.8 RLN56756.1 - 2.4 8.1 7.4 4.8 7.2 0.2 3.2 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) ABC2_membrane PF01061.24 RLN56782.1 - 1.9e-35 122.2 37.7 9.2e-30 103.6 21.0 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN56782.1 - 3.9e-17 63.1 0.0 7e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN56782.1 - 1.3e-06 28.5 0.1 0.062 13.1 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system PDR_CDR PF06422.12 RLN56782.1 - 0.00011 22.0 0.0 0.0083 16.0 0.0 2.7 2 0 0 2 2 2 1 CDR ABC transporter RsgA_GTPase PF03193.16 RLN56782.1 - 0.0006 19.8 0.7 0.0034 17.3 0.2 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 RLN56782.1 - 0.0034 17.1 0.7 0.008 15.9 0.7 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN56782.1 - 0.0035 17.7 0.2 0.008 16.6 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 RLN56782.1 - 0.006 16.2 0.1 0.014 15.0 0.1 1.6 2 0 0 2 2 2 1 AAA domain DUF2399 PF09664.10 RLN56782.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) AAA_23 PF13476.6 RLN56782.1 - 0.059 13.9 0.5 0.22 12.0 0.3 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 RLN56782.1 - 0.095 12.4 0.5 0.19 11.4 0.5 1.5 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 RLN56782.1 - 0.095 12.3 0.2 0.16 11.5 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 RLN56782.1 - 0.15 11.5 0.1 0.45 9.9 0.1 1.7 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RLN56782.1 - 0.15 12.3 0.2 0.33 11.2 0.2 1.6 1 1 0 1 1 1 0 AAA domain GDP_Man_Dehyd PF16363.5 RLN56818.1 - 5.7e-61 206.7 0.0 3.6e-60 204.1 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RLN56818.1 - 2.4e-54 184.3 0.0 3e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 RLN56818.1 - 5.1e-22 78.2 0.0 6.2e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 RLN56818.1 - 1.6e-20 73.4 0.0 1.4e-19 70.3 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 RLN56818.1 - 3.7e-14 52.5 0.0 6.3e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 RLN56818.1 - 1.7e-08 33.9 0.0 3.6e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 RLN56818.1 - 2.1e-06 27.7 0.0 7.9e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 RLN56818.1 - 9.7e-06 25.2 0.0 4.5e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 RLN56818.1 - 8.2e-05 22.6 0.1 0.00042 20.3 0.1 2.1 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 RLN56818.1 - 0.02 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family NIF PF03031.18 RLN56819.1 - 6.8e-24 84.4 0.0 1.2e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF550 PF04447.12 RLN56819.1 - 0.12 12.5 0.0 0.42 10.7 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF550) SH2 PF00017.24 RLN56850.1 - 2.2e-05 24.5 0.0 4.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 SH2 domain AAA_16 PF13191.6 RLN56850.1 - 0.091 13.1 0.2 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Methyltr_RsmB-F PF01189.17 RLN56851.1 - 1.2e-36 126.2 0.0 4.8e-36 124.3 0.0 1.9 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 RLN56851.1 - 0.018 15.2 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase MFMR PF07777.11 RLN56851.1 - 0.14 12.7 0.1 0.3 11.6 0.1 1.4 1 0 0 1 1 1 0 G-box binding protein MFMR DUF4996 PF16387.5 RLN56852.1 - 0.11 13.0 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function SCNM1_acidic PF15805.5 RLN56852.1 - 0.42 10.4 2.1 0.82 9.4 2.1 1.4 1 0 0 1 1 1 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 FA_desaturase PF00487.24 RLN56855.1 - 2.8e-12 47.0 21.1 5.2e-12 46.1 21.1 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Csm1_N PF18504.1 RLN56857.1 - 2.8 8.4 8.9 0.81 10.1 0.6 2.6 3 0 0 3 3 3 0 Csm1 N-terminal domain Nup54 PF13874.6 RLN56857.1 - 9.6 6.3 9.9 12 6.0 0.8 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Caldesmon PF02029.15 RLN56859.1 - 0.075 11.8 13.2 0.41 9.4 0.8 2.1 2 0 0 2 2 2 0 Caldesmon DivIVA PF05103.13 RLN56859.1 - 0.42 10.7 6.3 0.28 11.2 1.1 2.3 2 0 0 2 2 2 0 DivIVA protein Csm1_N PF18504.1 RLN56859.1 - 0.56 10.6 10.2 1.1 9.7 1.4 2.8 2 0 0 2 2 2 0 Csm1 N-terminal domain GAS PF13851.6 RLN56859.1 - 7.7 5.8 12.9 5.5 6.3 5.8 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding FMN_red PF03358.15 RLN56860.1 - 4.1e-10 39.6 0.0 5.4e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 RLN56860.1 - 9.6e-06 25.4 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 RLN56861.1 - 1.6e-07 31.2 0.0 2.4e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 RLN56861.1 - 0.0018 18.0 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold MPDZ_u10 PF16667.5 RLN56862.1 - 0.015 16.1 0.7 6.1 7.8 0.2 2.6 2 0 0 2 2 2 0 Unstructured region 10 on multiple PDZ protein DUF309 PF03745.14 RLN56862.1 - 0.031 13.9 0.0 5.2 6.8 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF309) DUF5320 PF17253.2 RLN56862.1 - 0.42 11.7 2.6 36 5.5 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Gon7 PF08738.10 RLN56862.1 - 3 8.0 7.3 8.3 6.6 0.4 2.9 3 0 0 3 3 3 0 Gon7 family DUF4140 PF13600.6 RLN56862.1 - 8.6 6.9 14.1 13 6.3 0.5 3.5 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF2680 PF10925.8 RLN56862.1 - 9.6 6.3 11.1 25 4.9 1.3 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2680) Optomotor-blind PF11078.8 RLN56863.1 - 0.37 11.4 0.0 0.37 11.4 0.0 2.8 4 0 0 4 4 4 0 Optomotor-blind protein N-terminal region Arf PF00025.21 RLN56864.1 - 5.6e-63 211.5 0.0 6.6e-63 211.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RLN56864.1 - 1.9e-13 50.7 0.0 2.9e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 RLN56864.1 - 6.5e-12 45.3 0.5 1.3e-07 31.1 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 RLN56864.1 - 8.6e-10 38.4 0.0 1e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 RLN56864.1 - 8.7e-09 35.1 0.0 1.1e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 RLN56864.1 - 1e-07 31.5 0.0 1.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RLN56864.1 - 7.6e-05 22.8 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 RLN56864.1 - 0.00037 20.5 0.2 0.23 11.3 0.0 2.2 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 RLN56864.1 - 0.011 16.0 0.7 0.53 10.6 0.7 2.3 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 RLN56864.1 - 0.018 14.6 0.6 2.5 7.6 0.2 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 RLN56864.1 - 0.022 14.5 0.1 0.031 14.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 RLN56864.1 - 0.073 12.7 0.1 0.32 10.6 0.1 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain HTH_Mga PF08280.11 RLN56864.1 - 0.08 13.0 0.0 2.2 8.4 0.0 2.3 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain AIG1 PF04548.16 RLN56864.1 - 0.082 12.2 0.1 0.48 9.7 0.0 1.9 2 0 0 2 2 2 0 AIG1 family ABC_tran PF00005.27 RLN56864.1 - 0.096 13.2 0.1 0.11 13.1 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 RLN56864.1 - 0.15 11.7 0.2 0.2 11.2 0.2 1.6 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 RLN56864.1 - 0.24 10.8 0.0 5.3 6.4 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain PS_Dcarbxylase PF02666.15 RLN56904.1 - 8.7e-60 201.7 0.0 1.2e-59 201.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase eIF3_subunit PF08597.10 RLN56905.1 - 3.5e-36 125.3 13.0 4.9e-36 124.9 13.0 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Alpha-2-MRAP_N PF06400.11 RLN56905.1 - 0.13 12.2 0.1 0.13 12.2 0.1 2.6 3 0 0 3 3 3 0 Alpha-2-macroglobulin RAP, N-terminal domain Aldedh PF00171.22 RLN56906.1 - 4.1e-71 239.9 0.0 5.2e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1515 PF07439.11 RLN56906.1 - 0.14 12.2 0.3 3.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Mg_trans_NIPA PF05653.14 RLN56914.1 - 1.7e-34 119.3 12.4 2.2e-19 69.7 2.8 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA TMEM234 PF10639.9 RLN56914.1 - 0.0016 18.4 0.1 0.0062 16.6 0.1 2.0 1 0 0 1 1 1 1 Putative transmembrane family 234 UPF0060 PF02694.15 RLN56914.1 - 0.88 9.8 9.2 0.4 10.9 3.0 2.6 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family Sugarporin_N PF11471.8 RLN56914.1 - 3.2 7.8 5.4 24 5.0 2.2 3.2 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension RIX1 PF08167.12 RLN56915.1 - 8.5e-16 58.2 5.3 2.2e-15 56.9 5.3 1.7 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis Dopey_N PF04118.14 RLN56915.1 - 0.0045 16.2 0.4 0.0085 15.2 0.4 1.4 1 0 0 1 1 1 1 Dopey, N-terminal Spidroin_MaSp PF11260.8 RLN56915.1 - 0.022 15.0 0.3 0.096 13.0 0.3 2.2 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 Goodbye PF17109.5 RLN56915.1 - 0.089 13.2 0.9 22 5.5 0.1 2.8 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Pkinase PF00069.25 RLN56916.1 - 4.7e-63 213.0 0.0 8.3e-63 212.2 0.0 1.4 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN56916.1 - 5.5e-29 101.2 0.4 2.1e-28 99.3 0.4 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN56916.1 - 0.015 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family GAF_2 PF13185.6 RLN56917.1 - 1.3e-07 32.0 0.2 3.4e-07 30.6 0.2 1.7 1 0 0 1 1 1 1 GAF domain FYVE PF01363.21 RLN56917.1 - 3e-07 30.5 16.8 4.8e-07 29.8 12.0 2.8 3 0 0 3 3 3 1 FYVE zinc finger DEP PF00610.21 RLN56917.1 - 3.2e-05 23.9 0.0 6.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 RLN56917.1 - 0.0022 18.5 0.0 0.0043 17.6 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_4 PF15404.6 RLN56917.1 - 0.0057 16.5 1.4 0.01 15.6 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain Leu_zip PF15294.6 RLN56917.1 - 0.0077 15.8 2.7 0.012 15.2 2.7 1.2 1 0 0 1 1 1 1 Leucine zipper Urb2 PF10441.9 RLN56917.1 - 0.0099 15.8 1.3 0.023 14.6 1.3 1.6 1 0 0 1 1 1 1 Urb2/Npa2 family Filament PF00038.21 RLN56917.1 - 2 7.9 7.1 2.8 7.4 7.1 1.1 1 0 0 1 1 1 0 Intermediate filament protein FYVE_2 PF02318.16 RLN56917.1 - 2.1 8.6 7.1 7.7 6.8 7.1 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger GAF_2 PF13185.6 RLN56918.1 - 4.2e-06 27.1 0.0 8.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 GAF domain Med26 PF08711.11 RLN56918.1 - 0.058 13.4 0.2 0.14 12.2 0.2 1.6 1 0 0 1 1 1 0 TFIIS helical bundle-like domain GAF PF01590.26 RLN56918.1 - 0.076 13.6 0.2 0.18 12.4 0.0 1.7 2 0 0 2 2 2 0 GAF domain ERM PF00769.19 RLN56918.1 - 1.6 8.5 9.7 0.24 11.2 5.9 1.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family MetOD2 PF18548.1 RLN56918.1 - 6.6 6.9 5.9 2.7 8.2 3.3 1.6 2 0 0 2 2 2 0 Metanogen output domain 2 SWIB PF02201.18 RLN56958.1 - 1.9e-12 46.9 0.1 3e-12 46.2 0.1 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain Bac_surface_Ag PF01103.23 RLN56958.1 - 0.17 11.4 0.0 0.17 11.4 0.0 1.0 1 0 0 1 1 1 0 Surface antigen HNOBA PF07701.14 RLN56960.1 - 0.12 11.8 0.1 0.26 10.7 0.1 1.6 1 0 0 1 1 1 0 Heme NO binding associated FYVE PF01363.21 RLN56961.1 - 1.9e-17 63.2 10.7 3.5e-17 62.3 10.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger DUSP PF06337.12 RLN56961.1 - 5.8e-13 49.3 0.0 8.5e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 DUSP domain HrpB2 PF09487.10 RLN56961.1 - 0.089 13.2 0.1 0.17 12.3 0.1 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) FYVE_2 PF02318.16 RLN56961.1 - 0.52 10.5 8.6 0.19 11.9 5.5 1.8 1 1 1 2 2 2 0 FYVE-type zinc finger Prok-RING_4 PF14447.6 RLN56961.1 - 1.7 8.6 9.0 4.4 7.2 9.0 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN56961.1 - 1.7 8.6 13.0 3.5 7.7 13.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_2 PF14445.6 RLN56961.1 - 6.4 7.0 13.2 0.13 12.5 5.4 2.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 2 GCP_C_terminal PF04130.13 RLN57004.1 - 1.1e-66 225.4 9.5 1.9e-66 224.6 9.5 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal FG-GAP_2 PF14312.6 RLN57004.1 - 2e-62 207.2 55.4 1.7e-10 41.0 0.1 14.1 13 1 0 13 13 13 12 FG-GAP repeat GCP_N_terminal PF17681.1 RLN57004.1 - 4.5e-05 23.2 0.0 7.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Calx-beta PF03160.14 RLN57004.1 - 0.047 13.9 0.7 8.2 6.7 0.0 3.8 3 0 0 3 3 3 0 Calx-beta domain DUF3402 PF11882.8 RLN57005.1 - 1.6e-15 57.2 4.1 5.7e-06 25.7 0.0 3.1 2 1 1 3 3 3 3 Domain of unknown function (DUF3402) Bromodomain PF00439.25 RLN57006.1 - 3.2e-14 52.7 0.0 7.7e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 RLN57006.1 - 6.6e-06 25.9 5.7 6.6e-06 25.9 5.7 3.4 3 1 0 3 3 3 1 PHD-finger PHD_2 PF13831.6 RLN57006.1 - 0.95 9.1 10.1 0.14 11.7 5.2 2.2 2 0 0 2 2 2 0 PHD-finger DUF1414 PF07208.11 RLN57073.1 - 0.23 11.5 0.2 0.58 10.2 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) DUF3638 PF12340.8 RLN57074.1 - 7.5e-57 192.2 0.0 1.5e-56 191.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 RLN57074.1 - 5.3e-17 60.9 0.1 1.3e-16 59.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) DivIC PF04977.15 RLN57074.1 - 0.25 11.2 1.1 0.67 9.8 1.1 1.7 1 0 0 1 1 1 0 Septum formation initiator VIR_N PF15912.5 RLN57075.1 - 0.16 11.5 7.2 0.18 11.3 7.2 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal HAUS6_N PF14661.6 RLN57075.1 - 4.5 6.8 12.9 5.6 6.5 12.9 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus TPR_12 PF13424.6 RLN57107.1 - 2.1e-23 82.4 11.7 7e-11 42.3 0.1 4.4 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 RLN57107.1 - 1.1e-16 60.1 5.3 3.1e-06 26.9 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN57107.1 - 7.2e-10 38.2 9.8 0.13 12.5 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 RLN57107.1 - 1.3e-08 34.9 16.6 0.05 14.4 0.0 5.4 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN57107.1 - 1.9e-05 24.3 5.3 1.8 8.7 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN57107.1 - 0.0001 22.8 12.1 0.43 11.3 0.4 4.6 2 2 1 4 4 4 3 Tetratricopeptide repeat BTAD PF03704.17 RLN57107.1 - 0.00013 22.4 2.7 0.00064 20.2 0.0 2.7 2 2 0 2 2 2 1 Bacterial transcriptional activator domain TPR_19 PF14559.6 RLN57107.1 - 0.00029 21.3 12.7 0.31 11.6 0.2 4.9 1 1 5 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN57107.1 - 0.0018 18.4 11.6 0.085 13.1 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN57107.1 - 0.0092 15.6 4.5 1.1 9.0 1.1 3.8 3 0 0 3 3 3 1 TPR repeat TPR_17 PF13431.6 RLN57107.1 - 0.015 15.7 0.1 13 6.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN57107.1 - 0.067 13.4 3.9 5.3 7.3 0.0 3.7 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 RLN57107.1 - 0.12 12.4 3.3 3.4 7.7 0.1 3.2 1 1 2 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_1 PF00515.28 RLN57107.1 - 0.26 11.2 10.1 6.6 6.7 0.6 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC5 PF12862.7 RLN57107.1 - 0.54 10.4 2.7 8.4 6.5 0.3 3.2 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_6 PF13174.6 RLN57107.1 - 0.59 10.9 7.3 87 4.1 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat HisG PF01634.18 RLN57109.1 - 6.4e-54 182.2 0.1 9.1e-54 181.7 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 RLN57109.1 - 1.1e-22 79.9 0.1 2e-22 79.1 0.1 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 RLN57109.1 - 8.4e-06 25.9 0.1 1.3e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Sec7_N PF12783.7 RLN57109.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF4834 PF16118.5 RLN57110.1 - 8.8 7.4 10.2 32 5.6 7.6 3.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Rad60-SLD PF11976.8 RLN57112.1 - 4.9e-18 64.7 0.0 5.9e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 RLN57112.1 - 2.8e-11 43.0 0.0 3.3e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family OCRL_clath_bd PF16726.5 RLN57112.1 - 0.051 13.7 0.1 1.4 9.1 0.0 2.0 2 0 0 2 2 2 0 Inositol polyphosphate 5-phosphatase clathrin binding domain Y_phosphatase2 PF03162.13 RLN57113.1 - 2.3e-48 163.9 0.0 2.6e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 RLN57113.1 - 4.9e-06 26.7 0.0 1.1e-05 25.5 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family Dpy-30 PF05186.13 RLN57114.1 - 1.3e-18 66.3 0.3 2.2e-18 65.6 0.3 1.4 1 0 0 1 1 1 1 Dpy-30 motif LSM PF01423.22 RLN57115.1 - 3.4e-14 52.3 0.4 8.7e-14 51.0 0.1 1.7 2 0 0 2 2 2 1 LSM domain Pkinase PF00069.25 RLN57116.1 - 9.3e-48 162.9 0.0 1.3e-47 162.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN57116.1 - 5.5e-44 150.4 0.0 7.2e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 RLN57116.1 - 7.2e-07 28.9 2.8 0.00081 19.1 0.1 2.6 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RLN57116.1 - 0.00029 21.2 6.0 0.015 15.7 0.1 2.8 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) TMEM154 PF15102.6 RLN57116.1 - 0.00066 19.6 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family APH PF01636.23 RLN57116.1 - 0.0082 16.1 0.0 0.24 11.3 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family LRR_1 PF00560.33 RLN57116.1 - 0.0085 16.5 0.1 34 5.6 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 RLN57116.1 - 0.11 12.6 2.5 3.3 8.0 0.2 3.3 3 0 0 3 3 3 0 Leucine Rich repeat CD34_antigen PF06365.12 RLN57116.1 - 0.17 11.5 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family LRR_6 PF13516.6 RLN57117.1 - 0.094 12.8 0.1 4.3 7.6 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich repeat Pkinase PF00069.25 RLN57118.1 - 8.6e-49 166.3 0.0 1.3e-48 165.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN57118.1 - 4.2e-43 147.5 0.0 5.7e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 RLN57118.1 - 5.8e-12 45.6 7.6 2.9e-06 27.5 0.2 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN57118.1 - 5.6e-09 35.6 10.2 7.5e-06 25.6 0.8 3.3 1 1 2 3 3 3 3 Leucine rich repeat SKG6 PF08693.10 RLN57118.1 - 0.0013 18.1 2.3 0.0027 17.1 2.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LRR_1 PF00560.33 RLN57118.1 - 0.0027 18.0 3.8 32 5.6 0.0 5.0 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 RLN57118.1 - 0.0085 16.1 10.1 2.7 8.3 0.0 4.4 4 0 0 4 4 4 2 Leucine Rich repeat Adeno_E3_CR2 PF02439.15 RLN57118.1 - 0.01 15.6 0.6 0.02 14.6 0.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 RLN57118.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain APH PF01636.23 RLN57118.1 - 0.058 13.3 0.3 1.1 9.1 0.1 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family GRA6 PF05084.13 RLN57118.1 - 0.21 11.5 2.3 0.91 9.4 0.1 2.3 2 0 0 2 2 2 0 Granule antigen protein (GRA6) YL1 PF05764.13 RLN57119.1 - 9e-32 111.1 4.7 9e-32 111.1 4.7 2.4 2 0 0 2 2 2 1 YL1 nuclear protein BSP_II PF05432.11 RLN57119.1 - 0.29 10.8 9.0 0.14 11.8 2.5 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Neur_chan_memb PF02932.16 RLN57119.1 - 2.5 8.1 8.5 0.29 11.1 3.1 1.9 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PBP1_TM PF14812.6 RLN57119.1 - 3.6 8.0 18.2 2.1 8.8 1.4 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PQ-loop PF04193.14 RLN57120.1 - 8.3e-26 89.5 4.6 4.5e-12 45.6 0.2 2.5 2 0 0 2 2 2 2 PQ loop repeat Pkinase PF00069.25 RLN57121.1 - 1.8e-51 175.0 0.0 2.5e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN57121.1 - 3.3e-44 151.1 0.0 4.4e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 RLN57121.1 - 4.3e-10 39.2 4.6 5e-06 26.2 0.7 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RLN57121.1 - 2.2e-08 34.3 4.1 3.7e-05 24.0 0.7 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) SKG6 PF08693.10 RLN57121.1 - 0.0016 17.8 0.2 0.0032 16.8 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LRR_1 PF00560.33 RLN57121.1 - 0.0028 18.0 1.0 4.5 8.2 0.1 4.4 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 RLN57121.1 - 0.046 13.8 5.5 1.7 8.9 0.1 3.9 4 0 0 4 4 3 0 Leucine Rich repeat Syndecan PF01034.20 RLN57121.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain APH PF01636.23 RLN57121.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Adeno_E3_CR2 PF02439.15 RLN57121.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Beta-APP PF03494.13 RLN57121.1 - 0.93 9.4 2.8 4.4 7.2 1.7 2.3 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) Gram_pos_anchor PF00746.21 RLN57121.1 - 0.97 9.4 3.7 0.36 10.8 0.2 2.1 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Phage_Coat_B PF05356.11 RLN57121.1 - 3.5 7.6 6.4 0.33 10.9 0.6 2.3 2 0 0 2 2 2 0 Phage Coat protein B OrfB_Zn_ribbon PF07282.11 RLN57138.1 - 0.11 12.5 2.0 0.58 10.1 2.0 2.3 1 1 0 1 1 1 0 Putative transposase DNA-binding domain DUF736 PF05284.12 RLN57138.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF736) Tudor-knot PF11717.8 RLN57139.1 - 6.7e-06 25.9 1.2 2e-05 24.4 1.2 1.8 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain MBT PF02820.18 RLN57139.1 - 2.3e-05 24.6 0.1 3.8e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 mbt repeat Tudor_4 PF18358.1 RLN57139.1 - 0.0073 15.9 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain Suppressor_APC PF11414.8 RLN57139.1 - 0.02 14.9 0.3 0.037 14.1 0.3 1.5 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein DUSP PF06337.12 RLN57139.1 - 0.091 13.4 0.2 0.2 12.3 0.0 1.7 2 0 0 2 2 2 0 DUSP domain SAWADEE PF16719.5 RLN57139.1 - 0.3 11.1 1.2 0.31 11.1 0.2 1.5 2 0 0 2 2 2 0 SAWADEE domain Mid1 PF12929.7 RLN57153.1 - 1e-14 54.6 13.8 3.2e-14 53.0 13.8 1.6 1 1 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 RLN57153.1 - 0.00082 20.0 7.1 0.2 12.3 1.0 2.6 1 1 1 2 2 2 2 Fz domain DUF1387 PF07139.11 RLN57154.1 - 0.18 11.5 1.5 0.28 10.9 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) CDC27 PF09507.10 RLN57156.1 - 9.9 5.4 33.3 16 4.7 33.3 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MGC-24 PF05283.11 RLN57158.1 - 2.1 8.8 15.9 3.1 8.2 15.9 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin zf-BED PF02892.15 RLN57215.1 - 0.00062 19.7 0.9 0.0012 18.8 0.2 1.9 2 0 0 2 2 2 1 BED zinc finger DUF659 PF04937.15 RLN57215.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Cullin PF00888.22 RLN57215.1 - 0.072 11.7 0.0 0.093 11.3 0.0 1.1 1 0 0 1 1 1 0 Cullin family Desulfoferrod_N PF06397.12 RLN57215.1 - 0.1 12.3 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Dimer_Tnp_hAT PF05699.14 RLN57216.1 - 0.00016 21.4 0.6 0.00034 20.3 0.6 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF1515 PF07439.11 RLN57216.1 - 0.1 12.7 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) ABC2_membrane_3 PF12698.7 RLN57229.1 - 5.7e-33 114.5 22.8 2.2e-32 112.5 22.8 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 RLN57229.1 - 1.1e-32 113.3 0.0 6.1e-23 81.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN57229.1 - 7.3e-13 49.0 0.0 1.5e-05 24.9 0.0 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 RLN57229.1 - 0.0013 19.0 0.0 3.5 7.9 0.0 3.9 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit ABC2_membrane_2 PF12679.7 RLN57229.1 - 0.039 13.2 22.1 0.15 11.3 0.0 2.9 2 1 2 4 4 4 0 ABC-2 family transporter protein DUF5493 PF17597.2 RLN57229.1 - 3.8 7.8 6.3 1 9.7 1.3 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF5493) Arm PF00514.23 RLN57268.1 - 2.6e-05 24.1 0.3 2.6e-05 24.1 0.3 7.5 10 0 0 10 10 10 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN57268.1 - 0.0043 17.5 7.7 0.092 13.3 0.7 5.3 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.22 RLN57268.1 - 0.0087 16.2 6.2 16 6.1 0.0 6.3 5 0 0 5 5 5 1 HEAT repeat DUF374 PF04028.13 RLN57268.1 - 0.042 13.4 0.0 7.3 6.2 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF374) Ank_2 PF12796.7 RLN57269.1 - 2.1e-28 98.7 0.8 5.5e-10 39.7 0.2 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN57269.1 - 4.6e-15 54.2 0.1 0.0042 17.5 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 RLN57269.1 - 5.6e-15 55.5 0.0 2.3e-05 24.9 0.0 3.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN57269.1 - 1.3e-13 50.9 0.7 5.4e-06 26.6 0.0 4.2 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN57269.1 - 3.9e-11 42.9 0.0 0.097 13.2 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat p450 PF00067.22 RLN57270.1 - 3.4e-75 253.6 0.0 4.4e-75 253.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acyltransferase PF01553.21 RLN57271.1 - 6.1e-22 77.7 0.0 1.2e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 RLN57271.1 - 2e-09 37.4 0.0 3.9e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus EF-hand_8 PF13833.6 RLN57272.1 - 8.2e-17 60.8 0.4 1.1e-09 37.9 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN57272.1 - 2.4e-10 39.5 1.3 0.0074 16.1 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 RLN57272.1 - 6.1e-09 36.2 1.4 8e-07 29.4 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN57272.1 - 6.7e-09 34.7 1.5 7.6e-05 22.0 0.3 3.2 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 RLN57272.1 - 0.00023 21.0 0.3 0.59 10.1 0.1 2.7 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 RLN57272.1 - 0.0016 17.8 0.5 0.024 14.1 0.2 2.6 3 0 0 3 3 3 1 EF hand Cro PF09048.10 RLN57272.1 - 0.076 13.1 0.0 9.4 6.4 0.0 2.4 2 0 0 2 2 2 0 Cro HigB-like_toxin PF05015.13 RLN57284.1 - 0.11 12.9 0.4 0.25 11.8 0.4 1.5 1 0 0 1 1 1 0 RelE-like toxin of type II toxin-antitoxin system HigB DUF2689 PF10894.8 RLN57284.1 - 0.13 12.0 0.2 0.51 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2689) DUF4761 PF15958.5 RLN57285.1 - 0.011 15.9 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) bZIP_1 PF00170.21 RLN57285.1 - 0.055 13.6 12.6 0.52 10.4 5.4 2.3 1 1 1 2 2 2 0 bZIP transcription factor DUF3867 PF12983.7 RLN57285.1 - 0.058 13.5 0.7 0.092 12.8 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3867) HGAL PF15666.5 RLN57285.1 - 0.092 12.9 0.1 0.26 11.4 0.1 1.8 1 0 0 1 1 1 0 Germinal center-associated lymphoma EST1 PF10374.9 RLN57285.1 - 0.44 11.2 4.4 0.48 11.0 3.2 1.7 2 0 0 2 2 2 0 Telomerase activating protein Est1 FYVE_2 PF02318.16 RLN57285.1 - 1.7 8.9 4.8 3.5 7.9 4.8 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Tho2 PF11262.8 RLN57285.1 - 2.1 7.5 6.8 4.8 6.3 5.7 1.9 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Abhydrolase_1 PF00561.20 RLN57286.1 - 4.6e-05 23.2 0.0 5.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 RLN57286.1 - 0.0026 17.9 0.0 0.0035 17.4 0.0 1.2 1 0 0 1 1 1 1 TAP-like protein ACOX PF01756.19 RLN57287.1 - 5e-51 172.8 0.0 8.1e-51 172.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 RLN57287.1 - 5.2e-30 104.6 2.1 9.3e-30 103.8 2.1 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 RLN57287.1 - 1.3e-13 50.9 0.0 4.6e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Sulfate_transp PF00916.20 RLN57288.1 - 9.6e-17 60.8 15.4 9.6e-17 60.8 15.4 2.7 1 1 1 2 2 2 1 Sulfate permease family STAS PF01740.21 RLN57288.1 - 1.2e-07 31.4 0.1 2.3e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 RLN57288.1 - 2.7e-06 27.8 16.9 0.0031 17.9 3.9 3.2 2 1 0 2 2 2 2 Molybdate transporter of MFS superfamily Tmp39 PF10271.9 RLN57288.1 - 0.01 14.9 0.8 0.019 14.0 0.8 1.5 1 0 0 1 1 1 1 Putative transmembrane protein Exo84_C PF16528.5 RLN57296.1 - 4.9e-13 49.4 0.7 1.8e-12 47.5 0.7 2.0 1 0 0 1 1 1 1 Exocyst component 84 C-terminal PH PF00169.29 RLN57297.1 - 1.9e-08 34.8 0.4 6e-08 33.1 0.1 1.9 2 1 0 2 2 2 1 PH domain PH_6 PF15406.6 RLN57297.1 - 0.0024 18.1 0.1 0.0058 16.9 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Med25 PF11232.8 RLN57297.1 - 0.027 14.5 0.1 0.066 13.2 0.0 1.6 2 0 0 2 2 2 0 Mediator complex subunit 25 PTOV activation and synapsin 2 PH_13 PF16652.5 RLN57297.1 - 0.05 13.4 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain DEP PF00610.21 RLN57297.1 - 0.064 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DIL PF01843.19 RLN57297.1 - 0.077 13.3 0.2 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 DIL domain SVA PF05326.11 RLN57297.1 - 0.087 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Seminal vesicle autoantigen (SVA) RCC1 PF00415.18 RLN57298.1 - 3.4e-30 104.4 8.5 2.7e-10 40.7 0.1 5.9 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN57298.1 - 5.2e-16 58.0 10.8 1.7e-08 34.1 0.2 3.7 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat EF-hand_4 PF12763.7 RLN57298.1 - 8.8e-10 38.5 0.0 1.3e-08 34.7 0.0 2.4 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 RLN57298.1 - 1.5e-05 24.2 0.1 0.19 11.3 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RLN57298.1 - 9.3e-05 22.8 0.3 0.00028 21.3 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN57298.1 - 0.0049 16.7 0.0 2.8 8.1 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RLN57298.1 - 0.035 13.6 0.4 0.49 10.0 0.5 2.7 2 0 0 2 2 2 0 EF hand RCC1 PF00415.18 RLN57299.1 - 4.1e-07 30.5 0.0 0.014 16.0 0.0 2.1 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat Pro_CA PF00484.19 RLN57300.1 - 4.7e-06 27.0 0.0 7.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Carbonic anhydrase LSM PF01423.22 RLN57322.1 - 5.2e-20 70.9 0.2 6.5e-20 70.6 0.2 1.1 1 0 0 1 1 1 1 LSM domain NOB1_Zn_bind PF08772.11 RLN57323.1 - 0.36 11.0 2.8 0.22 11.7 0.5 1.8 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like PHD PF00628.29 RLN57323.1 - 0.72 9.8 10.1 2.1 8.3 10.1 1.8 1 1 0 1 1 1 0 PHD-finger PBP1_TM PF14812.6 RLN57323.1 - 3.2 8.2 24.8 0.55 10.6 5.1 3.1 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TDP43_N PF18694.1 RLN57325.1 - 3.3e-05 23.6 0.0 22 5.0 0.0 4.5 4 0 0 4 4 4 4 Transactive response DNA-binding protein N-terminal domain DUF2076 PF09849.9 RLN57325.1 - 0.038 14.0 0.0 28 4.6 0.0 3.3 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2076) MotB_plug PF13677.6 RLN57325.1 - 0.88 9.2 3.5 42 3.8 0.1 3.5 4 0 0 4 4 4 0 Membrane MotB of proton-channel complex MotA/MotB STE3 PF02076.15 RLN57325.1 - 7.2 5.7 19.6 2.5 7.2 0.2 4.5 4 0 0 4 4 4 0 Pheromone A receptor DUF3689 PF12463.8 RLN57326.1 - 3.6e-109 364.9 0.3 6.4e-109 364.0 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3689) Tub PF01167.18 RLN57327.1 - 5.5e-29 101.6 0.1 5.7e-28 98.3 0.1 2.2 1 1 0 1 1 1 1 Tub family SOG2 PF10428.9 RLN57327.1 - 1.7 7.7 15.1 2.1 7.5 15.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 RLN57327.1 - 4.3 6.1 9.6 5.6 5.7 9.6 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 RLN57327.1 - 4.4 5.8 9.7 5 5.6 9.7 1.1 1 0 0 1 1 1 0 Macoilin family TMEM154 PF15102.6 RLN57328.1 - 0.11 12.4 0.0 0.11 12.4 0.0 8.2 3 3 4 7 7 7 0 TMEM154 protein family Glyco_transf_22 PF03901.17 RLN57329.1 - 3.2e-79 267.1 19.9 3.9e-79 266.8 19.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family FAM184 PF15665.5 RLN57330.1 - 2.7e-42 144.9 44.5 2.7e-42 144.9 44.5 9.0 1 1 7 8 8 8 3 Family with sequence similarity 184, A and B F5_F8_type_C PF00754.25 RLN57331.1 - 3.3e-07 30.5 0.3 4.3e-07 30.1 0.3 1.3 1 0 0 1 1 1 1 F5/8 type C domain PCI PF01399.27 RLN57332.1 - 2.1e-13 50.7 0.1 5.1e-13 49.4 0.1 1.7 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 RLN57332.1 - 0.00073 19.3 0.3 0.0014 18.3 0.3 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 CSN4_RPN5_eIF3a PF18420.1 RLN57332.1 - 0.0035 17.5 0.1 0.0082 16.3 0.1 1.6 1 0 0 1 1 1 1 CSN4/RPN5/eIF3a helix turn helix domain Beta-Casp PF10996.8 RLN57333.1 - 0.075 13.3 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Beta-Casp domain MinE PF03776.14 RLN57355.1 - 7.3e-12 45.1 0.0 9.6e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Septum formation topological specificity factor MinE BCAS2 PF05700.11 RLN57355.1 - 0.14 11.9 0.0 0.16 11.6 0.0 1.0 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) BRCT PF00533.26 RLN57356.1 - 1.9e-08 34.5 0.0 0.0015 18.9 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 RLN57356.1 - 0.0007 20.0 0.0 0.014 15.7 0.0 2.6 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 RLN57356.1 - 0.00077 19.5 0.0 0.002 18.1 0.0 1.7 2 0 0 2 2 1 1 BRCA1 C Terminus (BRCT) domain zf-C3HC4 PF00097.25 RLN57356.1 - 0.0015 18.3 12.0 0.0026 17.6 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN57356.1 - 0.0035 17.2 12.2 0.0063 16.3 12.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RTT107_BRCT_5 PF16770.5 RLN57356.1 - 0.015 15.2 0.0 0.051 13.5 0.0 1.9 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain zf-RING_6 PF14835.6 RLN57356.1 - 0.11 12.4 3.7 0.25 11.2 3.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 RLN57356.1 - 0.16 12.1 11.2 0.32 11.2 11.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 RLN57356.1 - 0.17 12.2 12.7 0.32 11.4 12.7 1.4 1 0 0 1 1 1 0 Ring finger domain zf-UDP PF14569.6 RLN57356.1 - 0.21 11.7 1.3 0.5 10.5 1.3 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_UBOX PF13445.6 RLN57356.1 - 0.33 11.0 10.8 0.73 9.9 10.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger FYVE_2 PF02318.16 RLN57356.1 - 0.4 10.9 5.1 1.1 9.5 5.1 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_4 PF14570.6 RLN57356.1 - 0.51 10.2 6.3 1.1 9.1 6.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 RLN57356.1 - 4.6 7.6 9.5 9.8 6.6 9.5 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RLN57356.1 - 6.5 6.8 12.2 12 5.9 12.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain 2OG-FeII_Oxy PF03171.20 RLN57357.1 - 1.2e-24 86.7 0.0 2.2e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 RLN57357.1 - 6e-24 85.1 0.0 1.1e-23 84.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal ABC_tran PF00005.27 RLN57358.1 - 1.1e-55 187.8 0.0 8.4e-29 100.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 RLN57358.1 - 1.6e-44 152.4 39.6 7.3e-26 91.1 23.6 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 RLN57358.1 - 1.1e-18 68.1 10.9 8.7e-07 29.0 0.1 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RLN57358.1 - 8.4e-10 38.5 1.2 0.00021 20.8 0.0 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RLN57358.1 - 5.2e-06 26.1 1.1 0.048 13.4 0.1 3.1 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN57358.1 - 5.9e-06 26.9 0.3 0.06 13.8 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 RLN57358.1 - 0.012 15.3 0.0 24 4.5 0.0 3.2 2 1 0 3 3 3 0 AAA ATPase domain MMR_HSR1 PF01926.23 RLN57358.1 - 0.012 15.6 0.1 4.7 7.3 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RLN57358.1 - 0.017 15.0 0.2 9.2 6.1 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 RLN57358.1 - 0.027 13.4 0.4 5.4 5.9 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 RLN57358.1 - 0.036 14.5 0.0 9.8 6.6 0.0 2.9 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 RLN57358.1 - 0.059 13.3 0.0 0.44 10.4 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 RLN57358.1 - 0.07 12.8 0.4 7.2 6.2 0.1 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 RLN57358.1 - 0.11 12.9 0.1 23 5.3 0.0 3.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_27 PF13514.6 RLN57358.1 - 0.11 12.1 0.2 7.8 6.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RLN57358.1 - 0.15 12.7 0.0 20 5.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain ABC2_membrane PF01061.24 RLN57358.1 - 0.55 9.6 43.2 0.022 14.2 16.4 3.5 3 0 0 3 3 3 0 ABC-2 type transporter DUF87 PF01935.17 RLN57358.1 - 0.59 10.2 1.9 18 5.3 0.1 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain DSPc PF00782.20 RLN57359.1 - 4e-25 88.2 0.0 7.5e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Gelsolin PF00626.22 RLN57359.1 - 2.1e-05 24.3 0.0 0.0015 18.4 0.0 2.4 2 0 0 2 2 2 1 Gelsolin repeat Y_phosphatase PF00102.27 RLN57359.1 - 0.0019 17.8 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Thaumatin PF00314.17 RLN57360.1 - 0.0026 17.4 0.9 0.0072 16.0 0.6 1.9 1 1 1 2 2 2 1 Thaumatin family DUF1180 PF06679.12 RLN57360.1 - 0.069 13.6 1.1 0.15 12.5 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PIH1_CS PF18201.1 RLN57361.1 - 3.5e-10 40.2 0.0 4.8e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 PIH1 CS-like domain LRR_8 PF13855.6 RLN57362.1 - 3.1e-05 23.6 2.4 0.00031 20.4 2.3 2.3 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 RLN57362.1 - 7.6e-05 23.0 4.1 9.6e-05 22.7 0.4 2.9 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) DUF4741 PF15897.5 RLN57362.1 - 0.013 15.3 0.1 0.027 14.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4741) LRR_6 PF13516.6 RLN57362.1 - 0.11 12.6 1.5 12 6.2 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 RLN57362.1 - 0.17 12.6 6.1 1.1 10.1 0.3 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat DUF2401 PF10287.9 RLN57363.1 - 1.3e-59 201.6 3.5 1.3e-59 201.6 3.5 2.0 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 RLN57363.1 - 5.5e-12 45.9 0.1 2e-11 44.2 0.1 2.0 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Utp12 PF04003.12 RLN57364.1 - 0.0066 16.7 0.5 0.019 15.3 0.5 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family UTP15_C PF09384.10 RLN57364.1 - 0.0086 15.8 0.5 2.8 7.6 0.0 3.1 3 0 0 3 3 3 2 UTP15 C terminal Conotoxin PF02950.17 RLN57364.1 - 0.11 13.6 0.5 0.11 13.6 0.5 2.8 2 0 0 2 2 2 0 Conotoxin SPATA9 PF15824.5 RLN57364.1 - 2.1 7.5 3.9 0.84 8.9 0.4 2.0 3 0 0 3 3 3 0 Spermatogenesis-associated protein 9 DUF4200 PF13863.6 RLN57365.1 - 4.6e-23 81.9 27.3 4.6e-23 81.9 27.3 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) Syntaxin-6_N PF09177.11 RLN57365.1 - 0.065 13.8 15.4 0.16 12.6 4.0 2.8 2 1 0 3 3 3 0 Syntaxin 6, N-terminal FUSC PF04632.12 RLN57365.1 - 0.26 9.8 20.3 0.29 9.6 5.5 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family KMP11 PF03037.16 RLN57365.1 - 0.33 11.7 8.6 0.86 10.4 8.6 1.7 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 YnfE PF17452.2 RLN57365.1 - 1.7 9.0 11.2 0.26 11.6 1.0 3.0 3 1 0 3 3 3 0 Uncharacterized YnfE-like DUF1664 PF07889.12 RLN57365.1 - 2.8 8.0 12.6 0.28 11.2 1.8 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Pec_lyase_C PF00544.19 RLN57366.1 - 1.2e-07 31.5 6.7 1.2e-05 25.0 6.7 2.5 1 1 0 1 1 1 1 Pectate lyase Beta_helix_2 PF18835.1 RLN57366.1 - 0.18 11.6 2.7 0.33 10.8 0.4 2.6 2 0 0 2 2 2 0 Beta helix repeat of Inulin fructotransferase DUF2401 PF10287.9 RLN57367.1 - 1.5e-58 198.1 3.7 1.5e-58 198.1 3.7 1.9 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 RLN57367.1 - 2.4e-13 50.3 0.1 2.2e-12 47.2 0.0 2.6 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) Ifi-6-16 PF06140.13 RLN57381.1 - 8.4e-18 64.1 29.7 8.4e-18 64.1 29.7 1.7 1 1 0 1 1 1 1 Interferon-induced 6-16 family Tir_receptor_C PF07489.11 RLN57381.1 - 0.065 13.2 0.7 0.065 13.2 0.7 2.4 2 1 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus Sporozoite_P67 PF05642.11 RLN57381.1 - 0.11 10.5 4.6 0.13 10.3 4.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_tranf_2_3 PF13641.6 RLN57382.1 - 1.5e-05 25.0 0.0 2.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 RLN57383.1 - 0.0021 18.0 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 RLN57383.1 - 0.02 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 zf-HC5HC2H_2 PF13832.6 RLN57384.1 - 1e-20 73.9 11.5 1.8e-20 73.1 0.9 3.3 3 1 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RLN57384.1 - 2.5e-19 69.3 13.5 2.9e-19 69.1 0.0 3.6 4 0 0 4 4 4 1 PHD-like zinc-binding domain zf-RING-like PF08746.11 RLN57384.1 - 3.2e-06 27.3 16.8 0.0068 16.7 5.0 3.0 2 0 0 2 2 2 2 RING-like domain PHD PF00628.29 RLN57384.1 - 4.8e-06 26.4 26.3 1.3e-05 25.0 5.7 4.0 5 0 0 5 5 5 2 PHD-finger PHD_2 PF13831.6 RLN57384.1 - 0.00035 20.1 2.0 0.00035 20.1 2.0 3.4 3 1 0 3 3 3 2 PHD-finger BET PF17035.5 RLN57384.1 - 0.00088 19.4 0.0 0.35 11.1 0.0 2.4 2 0 0 2 2 2 2 Bromodomain extra-terminal - transcription regulation C1_2 PF03107.16 RLN57384.1 - 2.6 8.4 16.6 0.13 12.6 1.9 2.8 3 0 0 3 3 3 0 C1 domain Adeno_terminal PF02459.15 RLN57385.1 - 0.19 10.1 0.4 0.21 9.9 0.4 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Ssu72 PF04722.13 RLN57386.1 - 5.9e-54 182.5 0.0 7e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein PH PF00169.29 RLN57387.1 - 5.8e-13 49.3 0.0 2e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 RLN57387.1 - 7.9e-07 29.5 0.0 3.3e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Prok-TraM PF09228.10 RLN57387.1 - 0.002 18.5 0.4 0.002 18.5 0.4 2.3 2 0 0 2 2 2 1 Prokaryotic Transcriptional repressor TraM Ada3 PF10198.9 RLN57387.1 - 0.27 11.4 7.8 0.041 14.0 2.8 2.3 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 Spc7 PF08317.11 RLN57387.1 - 1.8 7.4 10.9 3.7 6.3 10.9 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 RLN57387.1 - 1.8 9.2 8.8 0.57 10.9 1.3 2.5 1 1 1 2 2 2 0 Initiation control protein YabA T2SSM PF04612.12 RLN57387.1 - 2.6 8.1 8.8 0.53 10.3 2.2 2.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Patched PF02460.18 RLN57388.1 - 3.7e-31 108.0 11.4 2e-22 79.2 1.2 2.3 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 RLN57388.1 - 1.7e-25 89.6 14.9 2.7e-25 89.0 6.6 3.8 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation NPC1_N PF16414.5 RLN57388.1 - 2.4e-18 66.6 13.6 4.4e-18 65.7 13.6 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus SET PF00856.28 RLN57389.1 - 5e-08 33.5 0.0 9.6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 SET domain TPR_2 PF07719.17 RLN57389.1 - 0.5 10.6 2.7 0.51 10.6 0.8 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat A_deaminase PF00962.22 RLN57390.1 - 2.7e-53 181.4 0.2 2.8e-30 105.8 0.2 2.1 2 0 0 2 2 2 2 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 RLN57390.1 - 0.0076 15.6 0.8 0.031 13.6 0.7 1.9 2 0 0 2 2 2 1 Amidohydrolase family DivIVA PF05103.13 RLN57391.1 - 0.0051 16.9 5.4 0.0051 16.9 5.4 3.3 3 1 0 3 3 3 1 DivIVA protein APG6_N PF17675.1 RLN57391.1 - 0.21 12.1 31.6 0.067 13.7 10.2 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region UPF0184 PF03670.13 RLN57391.1 - 1.5 9.2 7.4 4.3 7.8 0.5 3.1 2 2 0 2 2 2 0 Uncharacterised protein family (UPF0184) Mod_r PF07200.13 RLN57391.1 - 7.3 6.7 20.0 1.1 9.4 4.3 2.6 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein UPF0242 PF06785.11 RLN57391.1 - 7.7 6.6 19.0 2.1 8.4 8.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 RLN57391.1 - 8.2 4.2 14.9 0.2 9.6 4.4 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 RLN57391.1 - 9 6.8 10.0 18 5.8 0.1 3.9 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) MnmE_helical PF12631.7 RLN57392.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.6 2 0 0 2 2 2 0 MnmE helical domain HIP1_clath_bdg PF16515.5 RLN57392.1 - 6.1 7.5 5.9 20 5.9 0.7 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 WD40 PF00400.32 RLN57393.1 - 1e-08 35.6 1.3 2.3e-06 28.2 0.1 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 RLN57393.1 - 0.0043 16.1 0.8 0.011 14.8 0.0 2.0 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 RLN57393.1 - 0.0048 17.2 0.0 0.15 12.4 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1664 PF07889.12 RLN57393.1 - 3.9 7.5 23.3 4.6 7.3 1.3 4.0 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Sec34 PF04136.15 RLN57393.1 - 7.9 6.3 16.2 5.8 6.8 1.5 3.0 2 1 1 3 3 3 0 Sec34-like family Sugar_tr PF00083.24 RLN57394.1 - 4.8e-108 361.9 25.6 1.3e-81 274.8 12.7 2.9 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RLN57394.1 - 3.6e-30 105.1 32.2 3.4e-29 101.9 13.1 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 RLN57394.1 - 0.00061 18.3 1.2 0.00061 18.3 1.2 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector PSI PF01437.25 RLN57394.1 - 0.35 11.4 12.2 0.67 10.5 12.2 1.5 1 0 0 1 1 1 0 Plexin repeat DUF4148 PF13663.6 RLN57394.1 - 4.2 7.6 7.2 0.43 10.8 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) Sugar_tr PF00083.24 RLN57395.1 - 3.9e-85 286.4 14.7 7.1e-58 196.5 2.6 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RLN57395.1 - 6.1e-22 78.0 14.6 4e-18 65.5 5.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily PSI PF01437.25 RLN57395.1 - 0.0042 17.6 8.7 0.0091 16.5 8.7 1.6 1 0 0 1 1 1 1 Plexin repeat PSI_integrin PF17205.3 RLN57395.1 - 0.059 13.1 3.4 0.13 12.0 3.4 1.5 1 0 0 1 1 1 0 Integrin plexin domain START PF01852.19 RLN57396.1 - 3e-26 92.1 0.0 3.3e-15 56.1 0.0 2.7 3 0 0 3 3 3 2 START domain 2-oxoacid_dh PF00198.23 RLN57396.1 - 4.4e-26 91.8 0.0 6.2e-17 61.8 0.0 2.9 3 0 0 3 3 3 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) PH PF00169.29 RLN57396.1 - 3.4e-14 53.2 0.0 7.4e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN57396.1 - 0.00059 20.2 0.1 0.0047 17.3 0.1 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain SPR1 PF15356.6 RLN57396.1 - 0.035 14.6 0.7 0.069 13.7 0.0 1.8 2 0 0 2 2 2 0 Psoriasis susceptibility locus 2 CelD_N PF02927.14 RLN57396.1 - 0.21 12.5 1.9 2.3 9.2 0.3 2.9 2 0 0 2 2 2 0 Cellulase N-terminal ig-like domain Sugar_tr PF00083.24 RLN57397.1 - 8.6e-110 367.7 28.5 5.8e-86 289.1 14.4 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RLN57397.1 - 2.1e-29 102.5 30.9 4.2e-26 91.7 20.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily PSI PF01437.25 RLN57397.1 - 0.0011 19.5 7.9 0.002 18.6 7.9 1.5 1 0 0 1 1 1 1 Plexin repeat PSI_integrin PF17205.3 RLN57397.1 - 0.21 11.4 2.8 0.37 10.6 2.8 1.4 1 0 0 1 1 1 0 Integrin plexin domain PAP2_3 PF14378.6 RLN57408.1 - 0.12 12.0 2.1 0.3 10.7 2.1 1.6 1 0 0 1 1 1 0 PAP2 superfamily adh_short PF00106.25 RLN57435.1 - 3.9e-22 78.7 0.0 4e-21 75.4 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN57435.1 - 1.4e-10 41.1 0.1 2.3e-10 40.4 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN57435.1 - 0.0066 16.4 0.6 0.012 15.5 0.6 1.5 1 1 0 1 1 1 1 KR domain ACOX PF01756.19 RLN57436.1 - 5.9e-36 123.7 0.8 8.9e-36 123.1 0.2 1.6 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 RLN57436.1 - 1.1e-18 67.9 0.0 8.9e-18 65.0 0.0 2.5 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 RLN57436.1 - 1.2e-18 67.1 0.3 2.9e-18 65.9 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 RLN57436.1 - 6.5e-10 39.4 0.5 4.2e-09 36.8 0.5 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF5584 PF17822.1 RLN57436.1 - 0.04 13.4 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5584) PAH PF02671.21 RLN57437.1 - 2.3e-40 136.5 10.4 1.2e-17 63.7 3.0 4.2 3 1 1 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 RLN57437.1 - 2.7e-37 126.8 0.0 2.7e-37 126.8 0.0 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor Sin3a_C PF16879.5 RLN57437.1 - 4.2e-36 125.2 0.0 4.2e-36 125.2 0.0 3.7 4 1 0 4 4 4 1 C-terminal domain of Sin3a protein CDC24_OB1 PF17246.2 RLN57437.1 - 0.026 14.6 1.5 0.11 12.6 0.1 2.8 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 1 DUF1722 PF08349.11 RLN57437.1 - 0.063 13.6 5.1 9.3 6.6 0.1 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1722) PH PF00169.29 RLN57438.1 - 4.2e-05 24.0 0.0 5.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN57438.1 - 0.16 12.4 0.0 0.48 10.9 0.0 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain EMP24_GP25L PF01105.24 RLN57439.1 - 1.2e-11 44.8 0.0 2.2e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2806 PF10987.8 RLN57439.1 - 0.019 14.9 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2806) Adenyl_cycl_N PF12633.7 RLN57439.1 - 0.14 12.1 0.2 13 5.6 0.0 2.2 1 1 1 2 2 2 0 Adenylate cyclase NT domain Mannosyl_trans3 PF11051.8 RLN57440.1 - 1.3e-25 90.3 0.0 3.7e-25 88.8 0.0 1.7 1 1 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 RLN57440.1 - 0.032 14.2 1.2 0.11 12.4 0.2 2.0 2 0 0 2 2 2 0 Nucleotide-diphospho-sugar transferase TRP PF06011.12 RLN57441.1 - 1.2e-06 27.6 21.8 2.4e-06 26.6 12.1 2.3 1 1 1 2 2 2 2 Transient receptor potential (TRP) ion channel cNMP_binding PF00027.29 RLN57442.1 - 1.4e-09 37.9 0.1 0.0028 17.7 0.0 3.2 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Myb_DNA-binding PF00249.31 RLN57444.1 - 1.7e-30 105.0 2.8 2e-15 56.7 1.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN57444.1 - 5.5e-26 90.6 1.0 3e-18 65.8 0.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN57444.1 - 6.6e-08 32.3 0.6 0.00021 21.1 0.1 2.3 1 1 1 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 RLN57444.1 - 9.6e-06 25.7 0.4 0.029 14.5 0.0 2.5 2 0 0 2 2 2 2 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 RLN57444.1 - 0.023 14.7 0.1 0.93 9.5 0.0 2.4 1 1 1 2 2 2 0 SLIDE Thymidylat_synt PF00303.19 RLN57445.1 - 5.8e-116 386.3 0.0 7.2e-116 386.0 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 RLN57445.1 - 3.2e-41 140.7 0.0 7.6e-41 139.5 0.0 1.6 2 0 0 2 2 2 1 Dihydrofolate reductase cNMP_binding PF00027.29 RLN57457.1 - 1.8e-11 44.0 0.0 3.8e-08 33.3 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Reticulon PF02453.17 RLN57457.1 - 0.12 12.3 3.1 0.26 11.2 3.1 1.5 1 0 0 1 1 1 0 Reticulon DUF4446 PF14584.6 RLN57457.1 - 0.26 11.3 1.4 2 8.4 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) Ion_trans PF00520.31 RLN57457.1 - 4.1 6.6 8.9 8.6 5.5 7.6 1.9 1 1 0 1 1 1 0 Ion transport protein DUF1639 PF07797.14 RLN57457.1 - 5.3 7.1 6.2 1.7 8.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1639) DUF4407 PF14362.6 RLN57458.1 - 0.12 11.7 3.8 0.27 10.5 1.3 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Evr1_Alr PF04777.13 RLN57459.1 - 3.5e-19 69.1 0.3 7.3e-19 68.1 0.3 1.5 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.20 RLN57459.1 - 1.6e-18 66.6 0.2 2.9e-18 65.8 0.2 1.4 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 RLN57459.1 - 0.0068 15.8 0.0 0.03 13.7 0.0 1.9 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 RLN57459.1 - 0.12 12.8 0.1 0.25 11.7 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like eIF-5_eIF-2B PF01873.17 RLN57459.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Thioredoxin_4 PF13462.6 RLN57459.1 - 0.21 11.7 0.4 0.65 10.1 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin DUF4234 PF14018.6 RLN57459.1 - 0.36 11.0 2.3 30 4.9 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) Spc7 PF08317.11 RLN57460.1 - 0.0024 16.8 25.5 0.0024 16.8 25.5 5.5 2 2 3 5 5 5 2 Spc7 kinetochore protein DASH_Dam1 PF08653.10 RLN57460.1 - 0.15 11.9 8.5 21 5.0 0.1 5.9 6 0 0 6 6 6 0 DASH complex subunit Dam1 OAR PF03826.17 RLN57460.1 - 0.74 9.7 4.4 0.53 10.2 0.4 2.8 2 0 0 2 2 2 0 OAR domain CDO_I PF05995.12 RLN57460.1 - 1.1 8.6 5.2 0.48 9.7 1.1 2.6 2 1 1 3 3 3 0 Cysteine dioxygenase type I Baculo_PEP_C PF04513.12 RLN57460.1 - 3.7 7.6 24.0 4 7.5 5.0 5.0 2 2 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNA_GG_bind PF10258.9 RLN57485.1 - 4.7e-18 65.0 0.2 4.7e-17 61.8 0.2 2.2 1 1 0 1 1 1 1 PHAX RNA-binding domain GIT_CC PF16559.5 RLN57486.1 - 0.01 15.7 0.3 0.019 14.8 0.3 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 RLN57486.1 - 0.089 12.9 3.3 0.65 10.1 0.0 2.6 2 1 0 2 2 2 0 bZIP transcription factor tRNA-synt_2b PF00587.25 RLN57487.1 - 6.2e-30 104.5 0.0 1.7e-29 103.0 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 RLN57487.1 - 1.2e-14 54.2 0.0 2e-13 50.3 0.0 2.9 3 0 0 3 3 3 1 Anticodon binding domain Csm1_N PF18504.1 RLN57488.1 - 0.1 12.9 0.4 0.1 12.9 0.4 3.2 3 0 0 3 3 3 0 Csm1 N-terminal domain HTH_Tnp_Tc5 PF03221.16 RLN57491.1 - 9.2e-12 44.8 0.0 2.7e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.6 RLN57491.1 - 0.00024 20.8 0.1 0.00067 19.4 0.1 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_IclR PF09339.10 RLN57491.1 - 0.00049 19.9 0.3 0.0019 17.9 0.0 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.6 RLN57491.1 - 0.0017 17.9 0.1 0.0055 16.2 0.1 1.9 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 RLN57491.1 - 0.002 17.6 0.2 0.0054 16.2 0.2 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 RLN57491.1 - 0.0035 17.1 0.5 0.0071 16.1 0.5 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 RLN57491.1 - 0.0086 16.0 0.1 0.021 14.8 0.1 1.7 1 0 0 1 1 1 1 HTH domain CENP-B_N PF04218.13 RLN57491.1 - 0.039 13.6 0.1 0.098 12.3 0.1 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 RLN57491.1 - 0.04 14.0 0.1 0.11 12.7 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 RLN57491.1 - 0.081 12.8 0.0 0.081 12.8 0.0 3.2 3 1 1 4 4 4 0 AsnC-type helix-turn-helix domain HTH_5 PF01022.20 RLN57491.1 - 0.095 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_32 PF13565.6 RLN57491.1 - 8 7.2 7.0 7.4 7.3 0.1 3.4 3 1 0 3 3 3 0 Homeodomain-like domain DZR PF12773.7 RLN57492.1 - 0.0004 20.4 0.5 0.00079 19.4 0.5 1.5 1 0 0 1 1 1 1 Double zinc ribbon Hamartin PF04388.12 RLN57492.1 - 0.25 9.9 20.0 0.31 9.6 20.0 1.0 1 0 0 1 1 1 0 Hamartin protein zinc_ribbon_2 PF13240.6 RLN57492.1 - 0.43 10.4 7.7 1.7 8.5 1.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 RLN57492.1 - 1.1 9.0 9.5 2.4 7.9 0.2 3.5 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain RNA_POL_M_15KD PF02150.16 RLN57492.1 - 1.3 9.0 3.9 11 5.9 0.6 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf_UBZ PF18439.1 RLN57492.1 - 4.5 7.0 6.3 20 4.9 0.0 3.3 2 1 1 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-ribbon_3 PF13248.6 RLN57492.1 - 9.7 5.8 7.4 3.5 7.2 1.1 2.0 1 1 0 2 2 2 0 zinc-ribbon domain CoA_binding_3 PF13727.6 RLN57494.1 - 0.057 13.4 0.2 0.057 13.4 0.2 2.6 3 0 0 3 3 3 0 CoA-binding domain WD40 PF00400.32 RLN57507.1 - 5.5e-24 84.0 28.0 0.0081 17.0 0.0 13.9 13 1 0 13 13 13 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN57507.1 - 4.1e-06 27.0 0.0 22 5.4 0.0 7.5 7 2 0 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN57507.1 - 0.00033 19.4 0.0 0.12 11.0 0.0 3.4 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Lgl_C PF08596.10 RLN57507.1 - 0.011 14.5 0.2 2.5 6.7 0.1 3.2 3 0 0 3 3 3 0 Lethal giant larvae(Lgl) like, C-terminal Nucleoporin_N PF08801.11 RLN57507.1 - 0.12 11.1 0.7 1.3 7.7 0.0 2.7 2 0 0 2 2 2 0 Nup133 N terminal like TMEM43 PF07787.12 RLN57508.1 - 9e-45 153.0 0.0 2.9e-44 151.3 0.0 1.8 2 1 0 2 2 2 1 Transmembrane protein 43 Ysc84 PF04366.12 RLN57532.1 - 1.2e-33 115.6 0.2 2.3e-33 114.7 0.2 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator zf-ribbon_3 PF13248.6 RLN57532.1 - 0.0023 17.3 1.3 0.0058 16.0 1.3 1.7 1 0 0 1 1 1 1 zinc-ribbon domain VIR_N PF15912.5 RLN57532.1 - 0.093 12.3 3.5 0.16 11.6 3.5 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal zinc_ribbon_2 PF13240.6 RLN57532.1 - 0.5 10.1 8.8 10 6.0 8.8 2.7 1 1 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 RLN57532.1 - 7.5 6.7 13.5 0.083 12.9 0.8 3.3 3 0 0 3 3 3 0 Double zinc ribbon FAM176 PF14851.6 RLN57533.1 - 0.25 11.0 0.1 0.25 11.0 0.1 2.7 3 0 0 3 3 3 0 FAM176 family Zip PF02535.22 RLN57533.1 - 0.99 8.6 4.8 0.58 9.3 0.2 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Ribosomal_60s PF00428.19 RLN57533.1 - 2.1 9.0 10.9 0.2 12.2 5.5 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Glucan_synthase PF02364.15 RLN57534.1 - 7.1e-186 619.9 20.8 1.9e-167 558.9 8.9 2.6 2 1 1 3 3 3 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 RLN57534.1 - 2.5e-24 86.1 3.1 2.5e-23 82.8 3.1 2.6 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Sugar_tr PF00083.24 RLN57534.1 - 1.5e-17 63.6 21.6 1.5e-17 63.6 21.6 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN57534.1 - 2.8e-09 36.4 34.0 2.8e-09 36.4 34.0 5.2 3 2 3 6 6 6 1 Major Facilitator Superfamily FYVE PF01363.21 RLN57535.1 - 0.85 9.8 9.8 2.8 8.1 9.8 1.9 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN57535.1 - 6.6 7.0 12.0 0.52 10.5 7.0 1.7 2 0 0 2 2 2 0 FYVE-type zinc finger FYVE PF01363.21 RLN57536.1 - 1.1 9.4 17.4 2.7 8.2 17.4 1.7 1 0 0 1 1 1 0 FYVE zinc finger Sec3_C PF09763.9 RLN57537.1 - 0.013 13.9 1.1 0.023 13.1 1.1 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec3 Codanin-1_C PF15296.6 RLN57537.1 - 0.025 14.7 0.6 0.15 12.2 0.0 2.7 2 0 0 2 2 2 0 Codanin-1 C-terminus Chordopox_A20R PF05941.13 RLN57537.1 - 0.065 12.2 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus A20R protein FYVE PF01363.21 RLN57538.1 - 0.0054 16.8 6.1 0.012 15.7 6.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger PHD PF00628.29 RLN57538.1 - 0.013 15.4 6.2 0.024 14.5 6.2 1.5 1 0 0 1 1 1 0 PHD-finger Prim_Zn_Ribbon PF08273.12 RLN57538.1 - 0.11 12.8 3.7 0.24 11.7 3.7 1.5 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase zf-B_box PF00643.24 RLN57538.1 - 5.2 7.3 8.6 1.3 9.3 4.8 2.0 2 0 0 2 2 2 0 B-box zinc finger OrfB_Zn_ribbon PF07282.11 RLN57539.1 - 0.24 11.3 5.0 0.8 9.7 5.0 1.9 1 0 0 1 1 1 0 Putative transposase DNA-binding domain FYVE PF01363.21 RLN57539.1 - 0.84 9.8 9.1 1.7 8.8 9.1 1.5 1 0 0 1 1 1 0 FYVE zinc finger PHD_4 PF16866.5 RLN57539.1 - 2.8 8.1 7.9 8 6.6 7.8 1.9 1 1 0 1 1 1 0 PHD-finger FYVE_2 PF02318.16 RLN57540.1 - 0.017 15.4 10.6 0.039 14.2 10.6 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 RLN57540.1 - 5.2 7.3 11.6 13 6.0 11.6 1.7 1 0 0 1 1 1 0 FYVE zinc finger FYVE PF01363.21 RLN57541.1 - 0.51 10.5 5.9 1.2 9.3 5.9 1.7 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN57542.1 - 0.57 10.4 4.8 1.2 9.4 4.8 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Transformer PF06495.11 RLN57542.1 - 4.5 7.3 12.6 0.073 13.2 5.2 1.7 2 0 0 2 2 2 0 Fruit fly transformer protein PHD_4 PF16866.5 RLN57543.1 - 0.11 12.6 1.2 0.27 11.4 1.2 1.8 1 1 0 1 1 1 0 PHD-finger FYVE PF01363.21 RLN57543.1 - 8 6.7 8.5 0.47 10.6 2.9 1.9 2 0 0 2 2 2 0 FYVE zinc finger SprA-related PF12118.8 RLN57544.1 - 0.0024 17.1 9.4 0.0024 17.1 9.4 2.7 3 0 0 3 3 3 2 SprA-related family FYVE_2 PF02318.16 RLN57544.1 - 0.013 15.7 6.6 0.013 15.7 6.6 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger DUF1456 PF07308.13 RLN57544.1 - 0.016 15.6 0.2 0.14 12.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) FYVE PF01363.21 RLN57544.1 - 0.032 14.4 7.7 0.083 13.0 7.7 1.7 1 0 0 1 1 1 0 FYVE zinc finger DEAD PF00270.29 RLN57545.1 - 4e-15 56.0 0.1 7.8e-15 55.1 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 RLN57545.1 - 2.3e-06 28.3 0.9 6.5e-06 26.8 0.9 1.8 1 0 0 1 1 1 1 RecQ zinc-binding Helicase_C PF00271.31 RLN57545.1 - 0.00062 20.1 0.0 0.0022 18.3 0.0 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF4350 PF14258.6 RLN57545.1 - 0.017 15.6 0.6 2.7 8.5 0.1 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4350) SNF2_N PF00176.23 RLN57545.1 - 0.11 11.1 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain MFS_1 PF07690.16 RLN57546.1 - 5.3e-28 98.0 17.6 3.9e-20 72.1 5.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN57546.1 - 0.00022 20.2 0.9 0.0029 16.5 1.7 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 RLN57546.1 - 0.35 9.7 11.1 0.57 9.0 0.1 2.4 2 0 0 2 2 2 0 MFS_1 like family DUF4149 PF13664.6 RLN57546.1 - 1.9 8.9 6.7 6.7 7.1 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) FYVE_2 PF02318.16 RLN57548.1 - 0.14 12.4 8.7 0.12 12.6 6.9 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger FYVE PF01363.21 RLN57549.1 - 0.53 10.5 12.4 1.3 9.2 12.4 1.7 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN57549.1 - 5.4 7.3 8.8 13 6.1 8.8 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 RLN57550.1 - 1.3 9.2 16.3 3.4 7.9 16.3 1.7 1 1 0 1 1 1 0 FYVE zinc finger PDEase_I PF00233.19 RLN57569.1 - 7.8e-60 202.6 0.0 1.8e-59 201.4 0.0 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DnaJ PF00226.31 RLN57570.1 - 7.3e-15 54.9 2.4 2e-13 50.3 2.4 2.7 1 1 0 1 1 1 1 DnaJ domain DUF4524 PF15025.6 RLN57570.1 - 0.0087 15.8 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4524) DUF4407 PF14362.6 RLN57570.1 - 0.16 11.3 13.7 0.29 10.4 13.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 RLN57570.1 - 0.39 10.7 12.3 0.57 10.1 12.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SARAF PF06682.12 RLN57570.1 - 4.4 6.9 13.2 35 3.9 11.0 2.5 1 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Atg14 PF10186.9 RLN57570.1 - 5.3 6.0 11.0 8.7 5.3 11.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CDC45 PF02724.14 RLN57570.1 - 6 5.0 13.8 9.2 4.4 13.8 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF3336 PF11815.8 RLN57571.1 - 8.9e-21 74.0 0.1 1.5e-20 73.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 RLN57571.1 - 1.2e-16 61.5 0.0 2.1e-15 57.5 0.0 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase CDO_I PF05995.12 RLN57572.1 - 1.1e-28 99.7 0.0 1.5e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 RLN57572.1 - 0.00096 18.7 0.1 0.0028 17.1 0.1 1.8 1 1 0 1 1 1 1 PCO_ADO Syja_N PF02383.18 RLN57572.1 - 0.066 12.5 0.0 0.069 12.5 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain PP2C PF00481.21 RLN57583.1 - 1.3e-39 136.4 0.0 2.6e-39 135.4 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RLN57583.1 - 0.0014 18.3 0.8 0.003 17.2 0.7 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SET PF00856.28 RLN57596.1 - 2.3e-12 47.7 0.0 4.5e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 RLN57596.1 - 1.9e-10 40.6 13.1 1.9e-10 40.6 13.1 3.1 3 0 0 3 3 3 1 MYND finger HALZ PF02183.18 RLN57597.1 - 0.0023 18.1 0.8 0.0059 16.8 0.8 1.7 1 0 0 1 1 1 1 Homeobox associated leucine zipper Macoilin PF09726.9 RLN57597.1 - 0.051 12.2 4.8 0.064 11.8 4.8 1.1 1 0 0 1 1 1 0 Macoilin family TSC22 PF01166.18 RLN57597.1 - 0.063 13.6 1.7 3 8.2 0.4 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family HAUS6_N PF14661.6 RLN57597.1 - 5.6 6.5 9.7 0.087 12.4 2.2 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Pkinase_Tyr PF07714.17 RLN57598.1 - 2.2e-57 194.3 0.0 2.7e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN57598.1 - 8.9e-57 192.4 0.0 1.1e-56 192.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 RLN57598.1 - 0.00018 20.5 0.0 0.0002 20.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN57598.1 - 0.00042 20.3 0.1 0.038 13.9 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RLN57598.1 - 0.015 14.7 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 RLN57598.1 - 0.05 12.9 0.0 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RLN57598.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family EF-hand_7 PF13499.6 RLN57599.1 - 4.9e-31 107.0 0.8 3.3e-12 46.7 0.0 4.7 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 RLN57599.1 - 8.6e-26 87.5 0.6 0.00016 21.0 0.0 5.6 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 RLN57599.1 - 8.4e-22 75.2 2.9 0.00039 20.1 0.0 5.9 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 RLN57599.1 - 6.6e-21 73.9 4.5 2e-07 30.7 0.0 4.6 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 RLN57599.1 - 8.8e-18 62.9 1.1 0.002 17.5 0.1 5.6 5 0 0 5 5 5 4 EF hand Ank_2 PF12796.7 RLN57599.1 - 9.7e-17 61.3 0.5 0.00013 22.5 0.0 5.9 3 1 2 6 6 5 3 Ankyrin repeats (3 copies) WW PF00397.26 RLN57599.1 - 6.9e-15 54.8 7.1 8.6e-09 35.3 0.5 3.1 2 0 0 2 2 2 2 WW domain Ank_4 PF13637.6 RLN57599.1 - 4.4e-07 30.3 8.6 0.00029 21.3 0.0 6.2 5 2 2 7 7 7 2 Ankyrin repeats (many copies) SPARC_Ca_bdg PF10591.9 RLN57599.1 - 1.8e-05 25.0 1.7 0.0013 19.0 0.5 4.0 3 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Ank_5 PF13857.6 RLN57599.1 - 0.00027 21.2 10.8 1.7 9.1 0.0 6.8 7 2 1 8 8 8 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN57599.1 - 0.00058 20.1 8.3 7.8 7.4 0.0 7.9 8 0 0 8 8 8 1 Ankyrin repeat EF-hand_10 PF14788.6 RLN57599.1 - 0.00083 19.2 1.5 2 8.3 0.1 4.0 4 0 0 4 4 4 1 EF hand Glyco_hyd_101C PF17451.2 RLN57599.1 - 0.02 15.2 0.1 0.88 9.9 0.0 2.8 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain HSBP1 PF06825.12 RLN57599.1 - 0.039 13.8 1.1 0.73 9.7 0.2 2.7 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Dockerin_1 PF00404.18 RLN57599.1 - 0.18 12.0 0.1 2 8.7 0.0 2.7 3 0 0 3 3 2 0 Dockerin type I domain Ank PF00023.30 RLN57599.1 - 0.72 10.4 17.9 3.6 8.2 0.0 7.0 8 0 0 8 8 7 0 Ankyrin repeat Sugar_tr PF00083.24 RLN57600.1 - 7.8e-94 315.1 20.9 1.1e-93 314.6 20.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN57600.1 - 2.5e-27 95.7 57.1 4.1e-25 88.5 33.1 2.2 2 1 1 3 3 3 2 Major Facilitator Superfamily GST_N PF02798.20 RLN57600.1 - 1.2e-06 28.8 0.0 4.8e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 RLN57600.1 - 1.5e-06 28.5 0.0 4.7e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RLN57600.1 - 0.00035 20.7 0.1 0.00088 19.4 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RLN57600.1 - 0.00039 20.4 0.1 0.0015 18.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RLN57600.1 - 0.0015 18.8 0.0 0.0089 16.3 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain MFS_3 PF05977.13 RLN57600.1 - 0.031 12.7 10.0 0.068 11.5 0.6 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector GST_N_3 PF13417.6 RLN57601.1 - 2.1e-07 31.3 0.0 7.5e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RLN57601.1 - 3e-07 30.7 0.0 7.4e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RLN57601.1 - 1e-05 25.6 0.1 2.2e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RLN57601.1 - 5.3e-05 23.2 0.1 0.00019 21.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RLN57601.1 - 5.5e-05 23.3 0.1 0.00022 21.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RLN57601.1 - 0.00057 20.1 0.0 0.0017 18.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain 3HCDH_N PF02737.18 RLN57603.1 - 3.3e-09 36.9 0.0 2.5e-06 27.5 0.0 2.1 1 1 1 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Kinesin PF00225.23 RLN57604.1 - 1.7e-117 392.1 0.1 2.9e-117 391.3 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN57604.1 - 2.9e-27 95.4 0.1 1.9e-26 92.8 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding Bac_DnaA PF00308.18 RLN57604.1 - 0.051 13.4 0.1 0.051 13.4 0.1 2.0 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_22 PF13401.6 RLN57604.1 - 0.33 11.2 8.4 0.73 10.1 0.0 4.0 4 1 1 5 5 5 0 AAA domain YonK PF09642.10 RLN57614.1 - 0.11 12.7 0.2 0.19 11.9 0.2 1.3 1 0 0 1 1 1 0 YonK protein DUF4315 PF14193.6 RLN57615.1 - 3.1 7.9 9.6 5 7.2 6.5 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4315) tRNA-synt_1b PF00579.25 RLN57633.1 - 4.9e-97 324.8 0.0 5.2e-51 173.7 0.0 2.0 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Lipoprotein_20 PF13942.6 RLN57633.1 - 0.026 14.4 1.2 2.3 8.1 0.1 2.7 2 1 1 3 3 3 0 YfhG lipoprotein YfhO PF09586.10 RLN57635.1 - 0.014 13.7 1.1 0.077 11.2 1.1 1.8 1 1 0 1 1 1 0 Bacterial membrane protein YfhO PI3Ka PF00613.20 RLN57635.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CN_hydrolase PF00795.22 RLN57712.1 - 1.4e-46 159.0 0.0 1.7e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PALP PF00291.25 RLN57713.1 - 1.3e-42 146.3 0.2 1.4e-42 146.1 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Symplekin_C PF12295.8 RLN57731.1 - 7.4e-42 143.5 6.1 8.1e-42 143.4 4.6 1.8 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal Herpes_BBRF1 PF04793.12 RLN57731.1 - 0.059 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 BRRF1-like protein VHL_C PF17211.3 RLN57731.1 - 0.065 13.3 0.5 0.41 10.7 0.2 2.4 2 0 0 2 2 2 0 VHL box domain Aminotran_1_2 PF00155.21 RLN57732.1 - 2.5e-51 175.0 0.0 2.8e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 RLN57732.1 - 1.5e-05 24.5 0.3 2.1e-05 23.9 0.3 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 RLN57732.1 - 0.0015 18.0 0.3 0.0042 16.5 0.3 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 RLN57732.1 - 0.0017 17.0 0.0 0.0027 16.3 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 RLN57732.1 - 0.0023 17.0 0.1 0.0035 16.4 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 RLN57732.1 - 0.0056 15.5 0.5 0.016 13.9 0.5 1.9 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Pkinase PF00069.25 RLN57735.1 - 1.4e-44 152.5 0.0 2.1e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN57735.1 - 9.8e-41 139.7 0.0 1.4e-40 139.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 RLN57735.1 - 4.9e-14 52.7 0.0 1.2e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN57735.1 - 6.5e-10 38.4 0.0 0.002 18.5 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RLN57735.1 - 1.6e-09 37.9 0.4 3.5e-06 27.2 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN57735.1 - 8.4e-09 35.5 0.0 0.0013 19.1 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 RLN57735.1 - 2.7e-08 34.2 0.0 1.5e-07 31.8 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Kdo PF06293.14 RLN57735.1 - 2.6e-05 23.7 0.0 5.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RLN57735.1 - 0.016 14.8 0.0 0.043 13.4 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Kinase-like PF14531.6 RLN57735.1 - 0.02 14.2 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 RLN57735.1 - 0.024 14.6 0.0 0.064 13.2 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family DYW_deaminase PF14432.6 RLN57735.1 - 0.025 14.5 0.1 0.24 11.3 0.1 2.2 1 1 0 1 1 1 0 DYW family of nucleic acid deaminases HHV-5_US34A PF17087.5 RLN57735.1 - 0.25 11.5 1.2 0.6 10.3 1.2 1.6 1 0 0 1 1 1 0 Herpesvirus US34A protein family Herpes_pp85 PF04637.12 RLN57735.1 - 0.25 9.7 0.3 0.48 8.8 0.3 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Pkinase_Tyr PF07714.17 RLN57736.1 - 6.1e-30 104.4 0.0 1.2e-29 103.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN57736.1 - 6.4e-26 91.3 0.0 1.5e-25 90.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RLN57736.1 - 0.00017 21.0 0.0 0.00042 19.7 0.0 1.7 1 0 0 1 1 1 1 Kinase-like DUF2105 PF09878.9 RLN57736.1 - 0.023 14.4 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2105) DUF2408 PF10303.9 RLN57736.1 - 0.49 11.0 9.1 0.82 10.2 7.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF948 PF06103.11 RLN57736.1 - 1.1 9.6 4.4 9.9 6.5 1.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) zf-CHY PF05495.12 RLN57738.1 - 5.2e-12 46.1 16.0 1.1e-11 45.1 16.0 1.5 1 1 0 1 1 1 1 CHY zinc finger zf-RING_2 PF13639.6 RLN57738.1 - 6.1e-07 29.7 5.5 6.1e-07 29.7 5.5 2.8 1 1 1 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN57738.1 - 2.5e-05 24.0 1.2 2.5e-05 24.0 1.2 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN57738.1 - 0.0019 18.5 7.3 0.0019 18.5 7.3 2.5 1 1 1 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RLN57738.1 - 0.0022 17.9 6.7 0.0022 17.9 6.7 2.6 1 1 1 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RLN57738.1 - 0.0057 16.5 9.3 0.0057 16.5 9.3 2.6 1 1 1 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RLN57738.1 - 0.0065 16.5 0.9 0.0065 16.5 0.9 2.3 1 1 1 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 RLN57738.1 - 0.024 14.4 3.1 0.031 14.0 0.3 2.6 2 0 0 2 2 2 0 RING-like zinc finger FYDLN_acid PF09538.10 RLN57738.1 - 0.029 15.1 9.2 0.029 15.1 9.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Paf1 PF03985.13 RLN57738.1 - 0.27 10.2 6.4 0.34 9.8 6.4 1.1 1 0 0 1 1 1 0 Paf1 RRN3 PF05327.11 RLN57738.1 - 0.68 8.4 5.4 0.77 8.2 5.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 RLN57738.1 - 1.2 8.5 12.1 1.5 8.2 12.1 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 RLN57738.1 - 3.1 6.0 9.2 4 5.6 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 RLN57738.1 - 6.8 5.8 7.2 9.4 5.4 7.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PLATZ PF04640.14 RLN57739.1 - 0.0086 16.7 0.5 0.014 16.0 0.5 1.5 1 1 0 1 1 1 1 PLATZ transcription factor zf-FLZ PF04570.14 RLN57739.1 - 0.26 10.8 2.8 0.76 9.3 2.9 1.8 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 Orn_DAP_Arg_deC PF00278.22 RLN57763.1 - 1.9e-21 76.1 0.0 2.4e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain ABC2_membrane_3 PF12698.7 RLN57764.1 - 1.1e-33 116.8 21.2 4.1e-33 114.9 21.2 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 RLN57764.1 - 7.9e-33 113.9 0.0 3.7e-23 82.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN57764.1 - 1.2e-15 58.2 0.0 9.6e-07 28.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RLN57764.1 - 0.00047 19.7 0.0 0.018 14.5 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 RLN57764.1 - 0.0023 18.1 0.0 4.1 7.7 0.0 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit ABC2_membrane_2 PF12679.7 RLN57764.1 - 0.19 11.0 19.3 1.1 8.5 0.0 2.9 2 1 1 3 3 3 0 ABC-2 family transporter protein SDA1 PF05285.12 RLN57782.1 - 4.5e-49 167.7 40.7 3.3e-31 109.0 8.4 3.0 2 1 1 3 3 3 2 SDA1 NUC130_3NT PF08158.12 RLN57782.1 - 3.7e-21 75.2 0.4 1.1e-20 73.7 0.4 1.9 1 0 0 1 1 1 1 NUC130/3NT domain LOH1CR12 PF10158.9 RLN57782.1 - 1.3 9.0 6.0 6.2 6.9 0.7 2.8 2 0 0 2 2 2 0 Tumour suppressor protein Sas10_Utp3 PF04000.15 RLN57783.1 - 6.3e-08 33.1 0.0 2.1e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Trypsin_2 PF13365.6 RLN57783.1 - 1.7e-06 29.0 0.0 6.1e-06 27.2 0.0 2.0 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.13 RLN57783.1 - 0.058 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Pex2_Pex12 PF04757.14 RLN57784.1 - 1.1e-15 57.8 2.9 4.9e-15 55.7 2.8 1.9 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 RLN57784.1 - 1.5e-08 34.3 9.9 3e-08 33.4 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN57784.1 - 2.4e-08 34.2 11.2 2.4e-08 34.2 11.2 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 RLN57784.1 - 2.8e-08 33.5 9.0 5.9e-08 32.5 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN57784.1 - 6.4e-08 32.3 10.4 1.4e-07 31.2 10.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN57784.1 - 3.6e-07 29.9 10.6 6.7e-07 29.1 10.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN57784.1 - 3.4e-05 23.7 9.0 7.3e-05 22.7 9.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 RLN57784.1 - 4.3e-05 23.7 7.4 4.3e-05 23.7 7.4 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RLN57784.1 - 4.5e-05 23.4 10.4 0.00031 20.7 10.6 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 RLN57784.1 - 0.00015 21.8 10.6 0.00015 21.8 10.6 2.1 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 RLN57784.1 - 0.0073 16.3 3.4 0.0073 16.3 3.4 2.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2861 PF11060.8 RLN57784.1 - 0.11 12.1 0.1 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2861) zf-RING_4 PF14570.6 RLN57784.1 - 0.48 10.3 10.0 1 9.2 10.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain LSM PF01423.22 RLN57785.1 - 9.9e-20 70.0 0.2 1.2e-19 69.7 0.2 1.1 1 0 0 1 1 1 1 LSM domain Methyltransf_16 PF10294.9 RLN57786.1 - 2.4e-16 60.0 0.0 3.5e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Yippee-Mis18 PF03226.14 RLN57786.1 - 2.5e-09 37.3 0.0 4.7e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PrmA PF06325.13 RLN57786.1 - 0.041 13.3 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 RLN57786.1 - 0.091 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.15 RLN57786.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RIG-I_C-RD PF11648.8 RLN57786.1 - 0.25 11.6 1.7 0.64 10.3 0.1 2.1 2 0 0 2 2 2 0 C-terminal domain of RIG-I TF_Zn_Ribbon PF08271.12 RLN57786.1 - 3.5 7.2 6.4 2 8.0 0.1 3.0 3 0 0 3 3 3 0 TFIIB zinc-binding Pro_isomerase PF00160.21 RLN57787.1 - 4e-45 153.9 1.0 6.4e-45 153.3 0.0 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 RLN57787.1 - 1e-12 48.0 0.0 7.6e-09 35.3 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Rtf2 PF04641.12 RLN57787.1 - 7.7e-11 41.8 0.8 7.7e-11 41.8 0.8 3.0 3 1 0 3 3 3 1 Rtf2 RING-finger zf-NOSIP PF15906.5 RLN57787.1 - 2.9e-05 24.1 0.1 9.1e-05 22.5 0.1 1.8 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 RLN57787.1 - 0.017 14.9 2.6 0.018 14.8 0.4 2.3 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 RLN57787.1 - 0.029 14.6 0.0 0.18 12.0 0.0 2.3 2 1 0 2 2 2 0 U-box domain DUF1676 PF07898.13 RLN57787.1 - 0.084 12.9 0.2 0.22 11.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) zf-RING_UBOX PF13445.6 RLN57787.1 - 0.085 12.9 0.4 6.4 6.9 0.3 2.6 2 0 0 2 2 2 0 RING-type zinc-finger Pkinase_Tyr PF07714.17 RLN57787.1 - 0.099 11.9 0.1 0.23 10.7 0.1 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase Arm PF00514.23 RLN57788.1 - 1.8e-14 53.2 15.4 0.0026 17.8 0.2 7.1 7 1 1 8 8 8 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN57788.1 - 6.2e-05 22.9 1.8 1.8 9.0 0.0 4.2 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 RLN57788.1 - 0.00016 22.0 15.2 0.0073 16.7 0.8 4.1 2 1 3 5 5 5 4 HEAT repeats HEAT_EZ PF13513.6 RLN57788.1 - 0.00041 20.8 20.1 0.0035 17.8 0.9 4.7 5 0 0 5 5 5 2 HEAT-like repeat Arm_2 PF04826.13 RLN57788.1 - 0.0085 15.6 0.0 0.28 10.6 0.0 2.3 2 0 0 2 2 2 1 Armadillo-like Atx10homo_assoc PF09759.9 RLN57788.1 - 0.046 13.7 0.0 1.8 8.6 0.1 2.5 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain DUF1611_N PF17396.2 RLN57789.1 - 0.058 13.6 0.1 0.19 12.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain Ecl1 PF12855.7 RLN57789.1 - 9.2 7.4 16.5 14 6.8 16.5 1.2 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Sugar_tr PF00083.24 RLN57790.1 - 1e-104 350.9 22.4 1.2e-104 350.8 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN57790.1 - 3.8e-26 91.8 32.7 2.9e-19 69.2 4.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Caps_synth_CapC PF14102.6 RLN57790.1 - 0.4 11.1 5.8 0.17 12.3 0.4 2.7 2 0 0 2 2 2 0 Capsule biosynthesis CapC GlcNAc PF11397.8 RLN57792.1 - 1.5e-47 162.8 3.1 9.8e-39 133.8 0.1 3.2 2 1 1 3 3 3 2 Glycosyltransferase (GlcNAc) Med8 PF10232.9 RLN57792.1 - 0.62 9.6 2.5 0.63 9.6 0.0 2.0 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 BLM10_mid PF16507.5 RLN57793.1 - 2e-54 185.2 0.0 4.3e-54 184.1 0.0 1.5 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 RLN57793.1 - 1.4e-26 92.2 0.1 1e-25 89.5 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) Cnd1 PF12717.7 RLN57793.1 - 4.9e-05 23.4 1.0 0.064 13.3 0.0 3.6 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Fra10Ac1 PF09725.9 RLN57810.1 - 1.4e-44 151.1 1.9 2.4e-44 150.4 1.9 1.4 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 DUF755 PF05501.11 RLN57810.1 - 0.099 12.9 9.8 0.17 12.1 9.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Transformer PF06495.11 RLN57810.1 - 1.7 8.7 7.9 0.049 13.7 2.0 1.6 2 0 0 2 2 2 0 Fruit fly transformer protein OrfB_Zn_ribbon PF07282.11 RLN57811.1 - 0.12 12.3 1.2 0.4 10.6 1.2 2.0 1 1 0 1 1 1 0 Putative transposase DNA-binding domain Asp_Arg_Hydrox PF05118.15 RLN57812.1 - 5.2e-29 101.1 0.0 8e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase DUF4696 PF15767.5 RLN57813.1 - 0.0038 15.9 0.3 0.0038 15.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4696) ABC_membrane PF00664.23 RLN57859.1 - 3.5e-39 135.1 14.4 7.1e-32 111.2 9.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN57859.1 - 4.5e-17 62.9 0.0 8.6e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN57859.1 - 2.8e-07 30.2 0.6 0.00011 21.7 0.6 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 RLN57859.1 - 0.0002 21.5 0.4 0.00037 20.6 0.4 1.4 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 RLN57859.1 - 0.00074 19.5 0.3 0.002 18.0 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 RLN57859.1 - 0.0017 18.0 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 RLN57859.1 - 0.011 15.8 0.1 0.031 14.4 0.1 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 RLN57859.1 - 0.012 16.0 0.2 0.08 13.3 0.1 2.2 1 1 1 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 RLN57859.1 - 0.012 15.3 0.3 0.027 14.2 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.14 RLN57859.1 - 0.014 14.6 0.0 0.2 10.8 0.0 2.1 1 1 0 1 1 1 0 KAP family P-loop domain AIG1 PF04548.16 RLN57859.1 - 0.026 13.9 0.2 0.048 13.0 0.2 1.4 1 0 0 1 1 1 0 AIG1 family Zeta_toxin PF06414.12 RLN57859.1 - 0.11 11.7 0.1 0.22 10.8 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin TrwB_AAD_bind PF10412.9 RLN57859.1 - 0.13 11.2 0.0 0.27 10.1 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 RLN57859.1 - 0.17 12.2 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sulfate_transp PF00916.20 RLN57875.1 - 5.4e-15 55.0 18.9 8.1e-15 54.4 18.9 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 RLN57875.1 - 1.1e-06 28.6 0.0 2.7e-05 24.1 0.0 2.5 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 RLN57875.1 - 1.7e-05 24.4 0.0 5.2e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 STAS domain Myb_DNA-binding PF00249.31 RLN57936.1 - 4.3e-12 46.0 0.4 6.8e-12 45.4 0.4 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN57936.1 - 0.00069 19.5 0.1 0.0013 18.6 0.1 1.4 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 RLN57936.1 - 0.022 15.0 0.2 0.043 14.1 0.2 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain MobA_MobL PF03389.15 RLN57938.1 - 0.033 13.9 0.0 0.063 13.0 0.0 1.6 1 1 0 1 1 1 0 MobA/MobL family DUF4645 PF15488.6 RLN57938.1 - 1.4 8.3 11.0 4.3 6.7 0.5 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4645) Sugar_tr PF00083.24 RLN57939.1 - 8e-38 130.4 28.0 8.8e-27 94.1 4.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RLN57939.1 - 2.2e-24 86.1 42.1 7.5e-21 74.4 29.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 RLN57939.1 - 0.0021 16.5 1.2 0.0021 16.5 1.2 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF730 PF05325.11 RLN57941.1 - 0.12 12.4 0.4 0.99 9.4 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF730) Amelogenin PF02948.15 RLN57941.1 - 0.15 12.7 2.4 0.092 13.4 0.6 1.5 2 0 0 2 2 2 0 Amelogenin MFS_1 PF07690.16 RLN57942.1 - 5.4e-33 114.4 25.7 8e-33 113.8 25.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2368 PF10166.9 RLN57942.1 - 0.13 11.9 0.1 4.3 6.9 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) Mannosyl_trans3 PF11051.8 RLN57943.1 - 2.1e-25 89.6 0.0 4.7e-25 88.5 0.0 1.6 1 1 0 1 1 1 1 Mannosyltransferase putative DEK_C PF08766.11 RLN57944.1 - 1.6e-10 40.7 0.1 4.2e-10 39.4 0.1 1.7 1 0 0 1 1 1 1 DEK C terminal domain PWWP PF00855.17 RLN57944.1 - 2.8e-05 24.4 0.1 2.8e-05 24.4 0.1 3.4 3 1 0 3 3 3 1 PWWP domain Med26 PF08711.11 RLN57944.1 - 0.001 19.1 0.0 0.001 19.1 0.0 3.4 4 0 0 4 4 4 2 TFIIS helical bundle-like domain YL1 PF05764.13 RLN57944.1 - 0.82 9.7 27.8 0.032 14.4 21.9 1.6 2 0 0 2 2 2 0 YL1 nuclear protein Ndc1_Nup PF09531.10 RLN57944.1 - 2.2 6.9 5.2 2.8 6.5 5.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_S64 PF08192.11 RLN57944.1 - 2.5 6.5 11.2 3.5 6.0 11.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 Peptidase_M24 PF00557.24 RLN57945.1 - 1.2e-20 74.2 0.0 1.4e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Sugar_tr PF00083.24 RLN57948.1 - 3.9e-41 141.4 30.3 4e-39 134.8 30.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN57948.1 - 1.1e-31 110.1 57.2 1.1e-27 96.9 25.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily E1-E2_ATPase PF00122.20 RLN57949.1 - 1.1e-26 93.4 1.4 1.1e-26 93.4 1.4 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 RLN57949.1 - 8.1e-15 55.7 0.2 1.3e-08 35.4 0.0 2.9 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 RLN57949.1 - 2.3e-09 37.4 0.7 5.9e-09 36.1 0.7 1.7 1 1 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase PF13246.6 RLN57949.1 - 1.2e-06 28.5 0.0 3e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 RLN57949.1 - 0.00028 20.5 0.0 0.00066 19.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF3796 PF12676.7 RLN57949.1 - 0.14 12.6 0.2 0.5 10.8 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) MASE3 PF17159.4 RLN57949.1 - 9.2 5.8 9.1 0.7 9.5 0.4 2.9 3 0 0 3 3 3 0 Membrane-associated sensor domain Helicase_C PF00271.31 RLN57950.1 - 9.7e-11 42.0 0.0 1.5e-09 38.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 RLN57950.1 - 4.1e-08 33.2 0.0 1.5e-07 31.4 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RLN57950.1 - 9.5e-05 22.7 2.2 0.00056 20.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 RLN57950.1 - 0.0031 16.6 0.0 0.0069 15.5 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.6 RLN57950.1 - 0.0082 16.3 0.0 0.045 13.9 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 RLN57950.1 - 0.029 14.9 0.1 0.029 14.9 0.1 3.5 2 2 0 2 2 2 0 AAA domain AAA_19 PF13245.6 RLN57950.1 - 0.031 14.6 0.9 0.096 13.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 RLN57950.1 - 0.056 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 KaiC Pescadillo_N PF06732.11 RLN57951.1 - 5.7e-115 383.6 1.3 5.7e-115 383.6 1.3 2.3 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 RLN57951.1 - 4e-09 36.7 0.0 2.6e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Sugar_tr PF00083.24 RLN57952.1 - 1.3e-43 149.5 27.5 2.5e-29 102.5 4.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RLN57952.1 - 2.1e-29 102.5 35.6 2e-26 92.8 27.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 RLN57952.1 - 8e-05 21.2 0.6 0.00013 20.5 0.6 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 RLN57952.1 - 0.00022 19.6 3.4 0.00025 19.4 1.1 2.1 2 0 0 2 2 2 1 BT1 family FTR1 PF03239.14 RLN57952.1 - 0.0027 16.9 6.2 0.0079 15.4 6.2 1.8 1 0 0 1 1 1 1 Iron permease FTR1 family MFS_1_like PF12832.7 RLN57952.1 - 0.05 12.5 14.1 0.51 9.1 8.2 3.0 2 1 1 3 3 3 0 MFS_1 like family DUF5353 PF17304.2 RLN57952.1 - 0.45 10.3 7.1 0.63 9.8 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5353) MFS_1 PF07690.16 RLN57953.1 - 0.00024 20.1 0.2 0.00024 20.1 0.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN57953.1 - 0.00025 20.1 0.4 0.00028 19.9 0.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter PhoLip_ATPase_C PF16212.5 RLN57953.1 - 0.047 13.4 0.0 0.058 13.1 0.0 1.1 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal Ub-RnfH PF03658.14 RLN57962.1 - 0.002 18.5 0.0 0.003 17.9 0.0 1.3 1 0 0 1 1 1 1 RnfH family Ubiquitin RICTOR_N PF14664.6 RLN57964.1 - 1.8e-88 297.1 1.2 3e-88 296.4 1.2 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 RLN57964.1 - 2.5e-28 97.9 0.9 1.4e-27 95.5 0.9 2.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 RLN57964.1 - 3.4e-26 91.3 0.2 3.5e-23 81.6 0.0 3.5 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.6 RLN57964.1 - 3.7e-20 72.3 2.6 3.4e-19 69.2 0.0 3.5 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_EZ PF13513.6 RLN57964.1 - 3e-06 27.6 3.4 0.0092 16.5 0.1 4.3 3 1 1 4 4 4 3 HEAT-like repeat HEAT_2 PF13646.6 RLN57964.1 - 0.0059 17.0 9.1 0.17 12.3 0.0 5.2 5 0 0 5 5 5 1 HEAT repeats Arm PF00514.23 RLN57964.1 - 0.17 12.0 11.9 82 3.5 0.1 6.7 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat SNARE PF05739.19 RLN57965.1 - 6.2e-05 22.9 2.1 0.0001 22.2 0.3 2.3 3 0 0 3 3 3 1 SNARE domain Cir_Bir_Yir PF06022.11 RLN57965.1 - 0.028 13.9 0.0 0.036 13.6 0.0 1.1 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir MqsA_antitoxin PF15731.5 RLN57965.1 - 0.17 12.0 0.0 0.24 11.5 0.0 1.1 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA zf-Tim10_DDP PF02953.15 RLN57966.1 - 1.1e-14 53.8 2.6 1.1e-14 53.8 2.6 1.9 2 0 0 2 2 2 1 Tim10/DDP family zinc finger Hormone_recep PF00104.30 RLN57966.1 - 0.0037 16.9 5.2 0.0048 16.5 5.2 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Halogen_Hydrol PF10112.9 RLN57966.1 - 0.0089 16.1 1.3 0.01 15.9 0.3 1.5 2 0 0 2 2 2 1 5-bromo-4-chloroindolyl phosphate hydrolysis protein KMP11 PF03037.16 RLN57966.1 - 0.11 13.3 2.3 2.3 9.1 0.4 2.2 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 Nipped-B_C PF12830.7 RLN57967.1 - 4.6e-38 131.1 3.7 2.1e-37 128.9 0.0 3.4 3 1 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 RLN57967.1 - 0.089 13.1 0.5 1.6 9.1 0.0 3.0 2 1 1 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Ribosomal_L4 PF00573.22 RLN57969.1 - 5.7e-63 212.1 0.0 7.1e-63 211.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family TYW3 PF02676.14 RLN57970.1 - 2.7e-31 108.6 0.0 7.4e-31 107.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase TYW3 Met_10 PF02475.16 RLN57970.1 - 2.2e-25 89.6 0.0 6.1e-25 88.1 0.0 1.8 1 1 0 1 1 1 1 Met-10+ like-protein Kelch_4 PF13418.6 RLN57970.1 - 2.1e-18 66.1 1.8 8.7e-09 35.3 0.0 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 RLN57970.1 - 1.2e-17 63.2 3.1 7.3e-07 28.7 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 RLN57970.1 - 3.4e-17 62.0 0.6 2.7e-06 27.5 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 RLN57970.1 - 3.4e-16 59.1 3.2 8e-05 22.8 0.0 6.1 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN57970.1 - 2.7e-12 46.4 6.4 0.00018 21.4 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 RLN57970.1 - 1.2e-08 34.6 2.9 0.0016 18.3 0.0 4.7 5 1 0 5 5 5 2 Kelch motif Methyltransf_25 PF13649.6 RLN57970.1 - 0.00048 20.8 0.0 0.028 15.1 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 RLN57970.1 - 0.0045 16.5 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 RLN57970.1 - 0.068 12.8 0.0 0.19 11.3 0.0 1.8 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase ANAPC1 PF12859.7 RLN57971.1 - 2.7e-16 60.3 2.7 6e-16 59.2 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 RLN57971.1 - 5.4e-06 26.6 12.9 0.002 18.5 0.0 5.4 5 0 0 5 5 5 3 Proteasome/cyclosome repeat PAP_RNA-bind PF04926.15 RLN57972.1 - 1.5e-19 70.2 0.0 1.3e-18 67.2 0.0 2.1 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain CCDC84 PF14968.6 RLN57972.1 - 0.13 11.9 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 Coiled coil protein 84 Transp_cyt_pur PF02133.15 RLN58006.1 - 3.4e-26 92.0 30.7 4.2e-26 91.7 30.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin bPH_5 PF10882.8 RLN58006.1 - 0.077 13.1 0.1 0.24 11.5 0.1 1.8 1 0 0 1 1 1 0 Bacterial PH domain LRR_4 PF12799.7 RLN58007.1 - 9.8e-10 38.5 19.5 0.00088 19.6 0.6 8.8 6 2 1 9 9 9 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN58007.1 - 0.092 12.5 25.1 2.3 8.1 0.0 6.5 4 2 3 7 7 7 0 Leucine rich repeat Peptidase_C1 PF00112.23 RLN58008.1 - 5.9e-76 255.4 5.6 8.5e-76 254.8 5.6 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 RLN58008.1 - 6.6e-14 52.1 0.6 1.1e-13 51.4 0.6 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 RLN58008.1 - 8.3e-07 28.1 1.9 0.0011 17.8 0.4 2.3 2 0 0 2 2 2 2 Peptidase C1-like family PSI PF01437.25 RLN58008.1 - 4.1 8.0 15.5 0.31 11.6 8.0 2.6 2 0 0 2 2 2 0 Plexin repeat Cation_efflux PF01545.21 RLN58009.1 - 4.4e-29 101.7 6.4 5.3e-29 101.4 6.4 1.0 1 0 0 1 1 1 1 Cation efflux family DUF2545 PF10810.8 RLN58009.1 - 0.45 10.7 5.2 0.27 11.4 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2545) DUF1282 PF06930.12 RLN58009.1 - 0.73 9.6 6.8 1.7 8.4 6.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) Aldo_ket_red PF00248.21 RLN58024.1 - 1.4e-65 221.4 0.0 1.8e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Amidase PF01425.21 RLN58039.1 - 3.8e-83 279.9 0.9 3.5e-56 191.0 0.8 2.4 1 1 2 3 3 3 2 Amidase Myb_DNA-binding PF00249.31 RLN58052.1 - 4.6e-30 103.6 6.6 2.9e-14 53.0 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN58052.1 - 9.7e-22 77.0 3.2 5.4e-17 61.8 0.4 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 RLN58052.1 - 0.0015 18.7 0.8 0.0073 16.5 0.1 2.2 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 RLN58052.1 - 0.002 18.5 0.3 0.002 18.5 0.3 2.6 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN58052.1 - 0.0039 17.1 0.4 0.032 14.1 0.1 2.3 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 RLN58052.1 - 0.029 14.4 0.0 0.095 12.7 0.0 1.8 1 0 0 1 1 1 0 SLIDE Exo70 PF03081.15 RLN58052.1 - 0.59 9.1 1.6 7.5 5.5 1.6 2.2 1 1 0 1 1 1 0 Exo70 exocyst complex subunit Myb_DNA-bind_2 PF08914.11 RLN58052.1 - 2.4 8.4 6.5 0.24 11.6 0.5 2.4 1 1 1 2 2 2 0 Rap1 Myb domain AA_permease_2 PF13520.6 RLN58053.1 - 2.8e-44 151.7 34.6 7.3e-44 150.3 24.0 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 RLN58053.1 - 5.7e-29 101.0 24.3 5.7e-29 101.0 24.3 1.8 1 1 1 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 RLN58053.1 - 2.3e-11 43.6 3.9 2.3e-11 43.6 3.9 3.8 3 1 0 3 3 3 1 C-terminus of AA_permease Phage_holin_2_3 PF16080.5 RLN58053.1 - 2.3 8.0 9.7 0.72 9.7 2.7 3.2 2 0 0 2 2 2 0 Bacteriophage holin family HP1 DUF2417 PF10329.9 RLN58053.1 - 2.3 7.6 14.0 0.13 11.6 2.4 2.6 3 0 0 3 3 3 0 Region of unknown function (DUF2417) DBD_Tnp_Mut PF03108.15 RLN58064.1 - 0.00055 19.9 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 MuDR family transposase Beach PF02138.18 RLN58077.1 - 5.9e-116 386.7 1.3 8.9e-116 386.1 0.6 1.7 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 RLN58077.1 - 9.1e-21 73.8 0.0 4.7e-20 71.5 0.0 2.3 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.32 RLN58077.1 - 0.00013 22.7 3.7 0.14 13.0 0.2 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF4704 PF15787.5 RLN58077.1 - 0.0058 15.9 0.7 0.0058 15.9 0.7 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) Anoctamin PF04547.12 RLN58078.1 - 9.7e-05 21.4 2.3 0.00015 20.8 2.3 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel PTR2 PF00854.21 RLN58080.1 - 3.3e-76 256.7 4.6 6.7e-76 255.7 4.6 1.5 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 RLN58080.1 - 4e-10 39.1 42.5 1.1e-07 31.1 7.2 3.8 1 1 3 4 4 4 4 Major Facilitator Superfamily DUF2755 PF10954.8 RLN58080.1 - 1 9.3 3.8 0.98 9.4 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2755) GRIP PF01465.20 RLN58098.1 - 0.048 13.6 0.0 0.068 13.1 0.0 1.2 1 0 0 1 1 1 0 GRIP domain Pirin PF02678.16 RLN58099.1 - 2.7e-29 101.3 0.0 5.3e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 RLN58099.1 - 1.8e-27 95.7 0.0 5.4e-27 94.2 0.0 1.7 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin_C_2 PF17954.1 RLN58099.1 - 0.0097 16.1 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain Cauli_VI PF01693.16 RLN58100.1 - 3.1e-31 107.4 3.5 7.2e-16 58.2 0.3 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 RLN58100.1 - 1e-28 100.3 0.0 1.5e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 RNase H SBP_bac_11 PF13531.6 RLN58101.1 - 5.1e-15 55.8 0.2 6.6e-15 55.5 0.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Csd3_N PF18059.1 RLN58111.1 - 0.015 15.8 0.4 0.022 15.3 0.4 1.5 1 1 0 1 1 1 0 Csd3 N-terminal zf-HC5HC2H_2 PF13832.6 RLN58112.1 - 1.8e-19 69.9 16.2 4.7e-15 55.7 2.1 3.2 3 0 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RLN58112.1 - 6.1e-12 45.6 0.7 6.1e-12 45.6 0.7 4.5 4 1 0 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.6 RLN58112.1 - 3.8e-09 36.0 3.2 3.8e-09 36.0 3.2 3.4 4 0 0 4 4 4 1 PHD-finger PHD PF00628.29 RLN58112.1 - 1.7e-05 24.6 6.9 1.7e-05 24.6 6.9 3.4 4 0 0 4 4 4 2 PHD-finger Ada3 PF10198.9 RLN58112.1 - 0.02 15.0 1.6 0.11 12.7 1.6 2.3 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 Prok-RING_1 PF14446.6 RLN58112.1 - 0.58 10.1 11.3 0.04 13.9 3.5 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 RLN58112.1 - 3.2 7.7 12.8 0.24 11.3 1.1 3.3 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PIP5K PF01504.18 RLN58113.1 - 1e-67 228.3 0.0 2.1e-67 227.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_2 PF00002.24 RLN58113.1 - 0.0015 17.8 7.7 0.0034 16.7 4.5 2.2 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Phage_holin_3_6 PF07332.11 RLN58113.1 - 0.021 14.8 4.5 3.6 7.7 0.1 2.7 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III zinc_ribbon_4 PF13717.6 RLN58113.1 - 0.73 9.8 2.6 0.63 10.0 0.4 2.0 2 0 0 2 2 2 0 zinc-ribbon domain DUF2207 PF09972.9 RLN58113.1 - 1.3 7.7 6.1 4.7 5.9 0.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) CHORD PF04968.12 RLN58114.1 - 2.5e-43 146.6 25.0 1.7e-21 76.7 6.5 2.4 2 0 0 2 2 2 2 CHORD BTK PF00779.19 RLN58114.1 - 0.68 9.8 12.4 0.63 9.9 0.2 3.7 3 0 0 3 3 3 0 BTK motif CCDC-167 PF15188.6 RLN58115.1 - 2.6e-14 53.3 28.2 0.0052 17.1 0.2 6.4 4 2 0 5 5 5 4 Coiled-coil domain-containing protein 167 Fer4_24 PF18109.1 RLN58115.1 - 1.2e-05 25.4 5.4 0.28 11.5 0.1 4.1 3 0 0 3 3 3 2 Ferredoxin I 4Fe-4S cluster domain HMMR_N PF15905.5 RLN58115.1 - 0.00044 19.8 7.8 0.00044 19.8 7.8 5.6 1 1 2 5 5 5 3 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 RLN58115.1 - 0.0034 17.4 71.6 0.018 15.1 9.4 6.9 1 1 4 6 6 6 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 RLN58115.1 - 0.013 15.5 39.5 0.32 11.1 1.3 6.6 3 2 2 6 6 6 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 RLN58115.1 - 0.014 15.4 57.7 0.07 13.2 4.0 7.3 1 1 7 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus Strep_SA_rep PF06696.11 RLN58115.1 - 0.043 13.8 8.7 3.9 7.6 0.1 4.3 4 0 0 4 4 4 0 Streptococcal surface antigen repeat Csm1_N PF18504.1 RLN58115.1 - 0.099 13.0 63.6 0.3 11.5 0.8 11.6 4 3 7 12 12 12 0 Csm1 N-terminal domain DUF5595 PF18077.1 RLN58115.1 - 0.4 10.8 10.8 7.7 6.7 0.1 5.0 4 2 0 4 4 4 0 Domain of unknown function (DUF5595) HALZ PF02183.18 RLN58115.1 - 2 8.7 24.1 7.7 6.8 0.7 7.2 8 0 0 8 8 8 0 Homeobox associated leucine zipper Img2 PF05046.14 RLN58115.1 - 2.1 8.7 3.6 13 6.1 0.2 4.1 3 1 0 4 4 4 0 Mitochondrial large subunit ribosomal protein (Img2) Leu_zip PF15294.6 RLN58115.1 - 2.1 7.8 64.6 0.45 10.0 3.8 5.4 1 1 3 5 5 5 0 Leucine zipper DUF3584 PF12128.8 RLN58115.1 - 3.1 5.2 79.8 0.012 13.1 37.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 RLN58115.1 - 3.6 7.0 67.7 0.71 9.3 8.0 5.1 1 1 4 5 5 5 0 Golgin subfamily A member 5 TMF_TATA_bd PF12325.8 RLN58115.1 - 3.7 7.8 68.7 0.43 10.8 5.1 7.7 3 2 4 8 8 7 0 TATA element modulatory factor 1 TATA binding CALCOCO1 PF07888.11 RLN58115.1 - 4.4 6.0 76.2 0.074 11.9 27.1 4.0 1 1 4 5 5 5 0 Calcium binding and coiled-coil domain (CALCOCO1) like NPV_P10 PF05531.12 RLN58115.1 - 6.7 7.3 42.7 8.1 7.0 2.2 8.5 3 2 7 10 10 9 0 Nucleopolyhedrovirus P10 protein cNMP_binding PF00027.29 RLN58116.1 - 8.1e-59 195.7 1.3 1.5e-20 73.1 0.0 4.4 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Pkinase PF00069.25 RLN58116.1 - 1.3e-56 191.9 0.0 1.9e-56 191.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN58116.1 - 1.3e-27 96.7 0.0 2e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 RLN58116.1 - 0.0044 16.1 0.0 0.0081 15.2 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 RLN58116.1 - 0.011 15.1 0.0 0.032 13.5 0.0 1.8 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 RLN58116.1 - 0.013 15.5 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_4 PF12799.7 RLN58117.1 - 1.3e-07 31.8 24.5 1.1e-05 25.7 2.4 4.7 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN58117.1 - 8.3e-06 25.5 7.7 8.3e-06 25.5 7.7 3.6 3 1 0 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 RLN58117.1 - 1.4e-05 24.7 6.9 0.0001 21.9 6.6 2.4 1 1 0 1 1 1 1 Leucine-rich repeat Aa_trans PF01490.18 RLN58118.1 - 2.6e-40 138.4 17.1 3.8e-40 137.9 17.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 RLN58119.1 - 1.1e-42 146.2 15.9 1.6e-42 145.6 15.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein LRR_4 PF12799.7 RLN58120.1 - 0.0055 17.1 0.2 0.15 12.5 0.1 3.1 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) Aa_trans PF01490.18 RLN58121.1 - 2.5e-41 141.8 12.5 3.4e-41 141.3 12.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein HD PF01966.22 RLN58122.1 - 6.8e-12 45.7 0.1 1.3e-11 44.8 0.1 1.5 1 0 0 1 1 1 1 HD domain PDEase_I PF00233.19 RLN58122.1 - 0.004 16.9 0.2 0.0084 15.9 0.2 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase ADH_N PF08240.12 RLN58123.1 - 1e-24 86.5 3.7 1e-24 86.5 3.7 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN58123.1 - 2e-16 60.2 0.0 3.1e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN58123.1 - 0.00038 19.9 0.0 0.0006 19.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 RLN58123.1 - 0.00095 20.2 0.0 0.0014 19.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 RLN58123.1 - 0.011 15.0 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Hexapep PF00132.24 RLN58124.1 - 1.9e-08 33.7 2.8 0.00011 21.8 0.1 3.8 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) WD40 PF00400.32 RLN58125.1 - 3.7e-12 46.6 7.0 0.21 12.5 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat PALB2_WD40 PF16756.5 RLN58125.1 - 7.8e-06 25.0 0.4 0.0012 17.9 0.2 2.5 2 0 0 2 2 2 2 Partner and localizer of BRCA2 WD40 domain eIF2A PF08662.11 RLN58125.1 - 0.00029 20.8 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 RLN58125.1 - 0.00067 19.4 1.4 6.5 6.4 0.1 4.1 4 1 0 4 4 4 2 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 RLN58125.1 - 0.032 14.5 1.0 0.74 10.1 0.1 3.5 4 1 2 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain Tap-RNA_bind PF09162.10 RLN58125.1 - 0.061 13.2 0.9 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Tap, RNA-binding TatC PF00902.18 RLN58126.1 - 0.025 14.4 2.4 0.035 13.9 2.4 1.2 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) DUF1418 PF07214.12 RLN58126.1 - 0.13 12.1 0.4 0.45 10.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) LRR_8 PF13855.6 RLN58128.1 - 0.0066 16.2 0.0 0.03 14.1 0.0 2.2 1 0 0 1 1 1 1 Leucine rich repeat LPG_synthase_TM PF03706.13 RLN58128.1 - 0.52 9.8 5.6 1.3 8.5 1.7 2.3 1 1 1 2 2 2 0 Lysylphosphatidylglycerol synthase TM region LRR_8 PF13855.6 RLN58129.1 - 6.3e-08 32.3 19.2 0.23 11.3 0.1 6.7 5 1 1 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 RLN58129.1 - 0.014 15.8 20.8 1.8 9.1 0.1 7.4 5 1 0 6 6 6 0 Leucine Rich repeats (2 copies) SHE3 PF17078.5 RLN58130.1 - 0.0064 16.2 13.2 0.0064 16.2 13.2 8.2 1 1 5 7 7 7 3 SWI5-dependent HO expression protein 3 HIP1_clath_bdg PF16515.5 RLN58130.1 - 0.014 16.0 12.2 0.014 16.0 12.2 13.3 3 2 12 15 15 15 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CENP-F_leu_zip PF10473.9 RLN58130.1 - 5.3 7.1 193.6 0.11 12.5 8.0 10.0 3 2 6 10 10 10 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 RLN58131.1 - 0.0056 16.8 42.7 0.3 11.1 11.2 3.1 2 1 1 3 3 3 3 Afadin- and alpha -actinin-Binding CBP_BcsQ PF06564.12 RLN58131.1 - 0.0069 15.9 5.2 0.032 13.7 0.2 2.1 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ Tropomyosin_1 PF12718.7 RLN58131.1 - 0.013 15.7 14.7 0.013 15.7 14.7 3.5 2 2 1 3 3 3 0 Tropomyosin like DUF2935 PF11155.8 RLN58131.1 - 0.03 14.6 1.3 0.26 11.6 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) MbeD_MobD PF04899.12 RLN58131.1 - 0.032 14.4 0.9 0.032 14.4 0.9 3.5 3 1 0 3 3 3 0 MbeD/MobD like LPP PF04728.13 RLN58131.1 - 0.05 14.0 0.3 0.05 14.0 0.3 4.0 3 2 1 4 4 4 0 Lipoprotein leucine-zipper Laminin_II PF06009.12 RLN58131.1 - 0.31 11.0 20.4 1.9 8.5 0.9 3.3 2 1 1 3 3 3 0 Laminin Domain II Hemocyanin_C PF03723.14 RLN58131.1 - 0.43 9.9 3.4 1.2 8.4 1.4 2.1 2 0 0 2 2 2 0 Hemocyanin, ig-like domain APG6_N PF17675.1 RLN58131.1 - 1.1 9.7 37.7 5.4 7.5 6.6 3.3 2 1 1 3 3 3 0 Apg6 coiled-coil region NPV_P10 PF05531.12 RLN58131.1 - 2.6 8.6 10.6 2.9 8.4 0.3 3.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4254 PF14063.6 RLN58131.1 - 2.8 7.7 14.9 0.26 11.1 2.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4254) TolA_bind_tri PF16331.5 RLN58131.1 - 3.2 7.9 34.3 0.062 13.4 7.4 3.9 2 1 1 4 4 4 0 TolA binding protein trimerisation YabA PF06156.13 RLN58131.1 - 7.4 7.3 22.6 4.9 7.9 7.5 3.5 2 1 1 3 3 3 0 Initiation control protein YabA NAD_binding_5 PF07994.12 RLN58161.1 - 1.3e-73 248.2 0.0 1.5e-73 248.0 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 RLN58161.1 - 2.5e-48 162.8 0.4 3.7e-48 162.3 0.4 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase ArfGap PF01412.18 RLN58163.1 - 6.1e-32 110.1 0.2 2.1e-31 108.4 0.2 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Armet PF10208.9 RLN58163.1 - 6.7e-13 48.8 3.8 1.6e-10 41.1 0.3 2.5 1 1 1 2 2 2 2 Degradation arginine-rich protein for mis-folding SAP PF02037.27 RLN58163.1 - 0.0014 18.4 0.0 0.0037 17.0 0.0 1.8 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 RLN58163.1 - 0.0027 17.4 0.0 0.0064 16.2 0.0 1.6 1 0 0 1 1 1 1 HeH/LEM domain Hydrolase_4 PF12146.8 RLN58179.1 - 1.6e-37 129.0 0.1 1.8e-25 89.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN58179.1 - 9.8e-14 52.5 0.4 4.6e-12 47.0 0.4 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN58179.1 - 0.00017 21.3 0.4 0.00039 20.2 0.4 1.6 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 RLN58179.1 - 0.00031 20.6 0.2 0.049 13.4 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Chlorophyllase PF07224.11 RLN58179.1 - 0.002 17.2 0.0 0.0034 16.4 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 RLN58179.1 - 0.0023 16.9 0.1 0.0033 16.4 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 RLN58179.1 - 0.033 13.6 0.0 0.11 12.0 0.0 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family Dynamitin PF04912.14 RLN58225.1 - 2e-50 172.3 5.3 2.5e-50 171.9 5.3 1.2 1 0 0 1 1 1 1 Dynamitin CLZ PF16526.5 RLN58225.1 - 0.00089 19.6 14.0 0.0098 16.2 0.3 5.3 4 2 1 5 5 5 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1073 PF06381.11 RLN58225.1 - 0.055 12.3 1.9 0.091 11.5 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1073) MIF4G PF02854.19 RLN58257.1 - 5.3e-08 32.8 0.0 6e-08 32.6 0.0 1.0 1 0 0 1 1 1 1 MIF4G domain GHL5 PF14872.6 RLN58257.1 - 0.014 13.4 0.0 0.016 13.3 0.0 1.0 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 Thump_like PF18096.1 RLN58258.1 - 0.13 12.2 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 THUMP domain-like Pkinase PF00069.25 RLN58290.1 - 1.5e-47 162.2 0.0 2.1e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN58290.1 - 8.2e-45 153.1 0.0 1e-44 152.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN58290.1 - 0.0017 18.3 0.0 0.012 15.6 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN58290.1 - 0.02 13.9 0.0 0.96 8.3 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 RLN58290.1 - 0.021 13.6 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase TMEM154 PF15102.6 RLN58290.1 - 0.097 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Pkinase PF00069.25 RLN58291.1 - 1.3e-48 165.7 0.0 1.8e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN58291.1 - 3e-47 161.1 0.0 3.8e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN58291.1 - 0.0014 18.6 0.1 0.034 14.1 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family TMEM154 PF15102.6 RLN58291.1 - 0.0076 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family DUF1593 PF07632.11 RLN58291.1 - 0.011 15.2 0.1 0.018 14.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) Pkinase_fungal PF17667.1 RLN58291.1 - 0.011 14.5 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase TPR_2 PF07719.17 RLN58291.1 - 0.085 13.0 0.3 0.58 10.4 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN58291.1 - 0.085 12.8 3.7 0.18 11.7 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN58291.1 - 0.11 12.3 0.2 21 5.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN58291.1 - 0.14 12.4 0.0 0.47 10.8 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Haspin_kinase PF12330.8 RLN58291.1 - 0.18 10.7 0.0 0.8 8.6 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain PLDc_2 PF13091.6 RLN58292.1 - 2.2e-13 50.3 0.0 1.1e-10 41.5 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 RLN58292.1 - 9.8e-08 31.9 2.4 0.015 15.5 0.2 3.1 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF2448 PF10476.9 RLN58292.1 - 0.011 15.6 0.7 0.019 14.8 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) Mucin PF01456.17 RLN58292.1 - 0.039 14.0 18.1 0.1 12.6 18.1 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein SGL PF08450.12 RLN58307.1 - 7.1e-39 133.8 0.1 9.1e-39 133.5 0.1 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 RLN58307.1 - 0.0052 16.9 0.0 0.097 12.8 0.0 2.6 2 0 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.20 RLN58307.1 - 0.075 13.2 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 Arylesterase ANAPC4_WD40 PF12894.7 RLN58307.1 - 0.18 12.1 0.0 0.98 9.8 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Reg_prop PF07494.11 RLN58307.1 - 0.39 11.1 1.5 31 5.3 0.1 4.0 4 0 0 4 4 4 0 Two component regulator propeller Inhibitor_I36 PF03995.13 RLN58308.1 - 0.068 13.1 2.2 0.36 10.8 2.2 2.1 1 1 0 1 1 1 0 Peptidase inhibitor family I36 RAP1 PF07218.11 RLN58343.1 - 0.81 7.9 3.3 1 7.6 3.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SIR2 PF02146.17 RLN58346.1 - 1.1e-53 181.8 0.0 1.8e-53 181.1 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 RLN58346.1 - 8.4e-05 22.3 0.1 0.42 10.4 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain CEP44 PF15007.6 RLN58371.1 - 1e-15 58.0 0.1 1.3e-15 57.7 0.1 1.1 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 COPIIcoated_ERV PF07970.12 RLN58371.1 - 6.2e-11 42.6 0.2 8.5e-11 42.1 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter JHY PF15261.6 RLN58372.1 - 1.1 10.0 10.0 0.29 11.8 6.4 1.7 2 0 0 2 2 2 0 Jhy protein Rrn6 PF10214.9 RLN58372.1 - 2.9 6.3 8.2 3.4 6.1 8.2 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Lipase_3 PF01764.25 RLN58373.1 - 8.6e-31 106.7 0.0 1.7e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DSPc PF00782.20 RLN58373.1 - 8.4e-20 70.9 0.0 1.3e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.20 RLN58373.1 - 9.2e-05 22.7 0.1 0.00027 21.1 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain Hydrolase_4 PF12146.8 RLN58373.1 - 0.0075 15.6 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Init_tRNA_PT PF04179.12 RLN58373.1 - 0.021 15.1 0.0 0.065 13.5 0.0 1.8 1 0 0 1 1 1 0 Rit1 DUSP-like domain Abhydrolase_5 PF12695.7 RLN58373.1 - 0.044 13.5 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Apyrase PF06079.11 RLN58373.1 - 0.067 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Apyrase PGAP1 PF07819.13 RLN58373.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.8 RLN58373.1 - 0.12 11.9 0.1 0.93 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) LRR_6 PF13516.6 RLN58374.1 - 1.5e-06 27.8 0.6 0.039 14.0 0.0 5.0 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 RLN58374.1 - 1.5e-06 28.5 0.0 0.11 13.0 0.0 3.7 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN58374.1 - 0.12 13.0 5.1 3.7 8.5 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat TFIIS_M PF07500.14 RLN58375.1 - 5.9e-18 65.4 0.0 1.4e-17 64.2 0.0 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Methyltransf_16 PF10294.9 RLN58375.1 - 0.00011 21.9 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase DUF3725 PF12523.8 RLN58375.1 - 0.12 12.7 0.1 0.32 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) COPIIcoated_ERV PF07970.12 RLN58376.1 - 4.2e-45 154.3 1.8 7.5e-45 153.5 1.8 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 RLN58376.1 - 4.4e-26 91.0 0.1 7.2e-26 90.4 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF3357 PF11837.8 RLN58394.1 - 0.032 14.7 0.2 0.038 14.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) BSD PF03909.17 RLN58419.1 - 1.4e-14 53.8 0.6 4.6e-09 36.1 0.3 2.9 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 RLN58419.1 - 3.3e-11 43.4 0.0 9.1e-11 41.9 0.0 1.8 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DUF2458 PF10454.9 RLN58419.1 - 0.0031 17.2 0.0 0.0031 17.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2458) Methyltransf_16 PF10294.9 RLN58420.1 - 9.4e-24 84.1 0.0 1.3e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 RLN58420.1 - 2.7e-08 33.6 0.0 3.8e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 RLN58420.1 - 7.6e-07 28.8 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 RLN58420.1 - 0.0036 18.0 0.0 0.011 16.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 RLN58420.1 - 0.088 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Abhydrolase_1 PF00561.20 RLN58421.1 - 0.00024 20.8 0.0 0.1 12.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Vut_1 PF02592.15 RLN58421.1 - 0.04 14.3 0.1 0.074 13.4 0.1 1.4 1 0 0 1 1 1 0 Putative vitamin uptake transporter DLH PF01738.18 RLN58421.1 - 0.066 12.8 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 RLN58421.1 - 0.076 13.6 1.0 0.65 10.6 0.0 2.4 1 1 1 3 3 3 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN58421.1 - 0.14 11.4 0.0 0.67 9.2 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PAE PF03283.13 RLN58422.1 - 3e-14 52.9 0.3 5.3e-14 52.1 0.3 1.3 1 0 0 1 1 1 1 Pectinacetylesterase SOG2 PF10428.9 RLN58422.1 - 1.2 8.2 32.0 1.7 7.8 32.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PAE PF03283.13 RLN58423.1 - 2.1e-13 50.2 0.1 4.6e-13 49.0 0.1 1.4 1 1 0 1 1 1 1 Pectinacetylesterase Abhydrolase_3 PF07859.13 RLN58423.1 - 0.062 13.2 0.0 0.45 10.3 0.1 2.5 2 1 0 2 2 2 0 alpha/beta hydrolase fold Med3 PF11593.8 RLN58423.1 - 1.5 7.9 13.2 2.7 7.1 13.2 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MFS_1 PF07690.16 RLN58424.1 - 8.6e-18 64.4 22.6 8.6e-18 64.4 22.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily ThiC_Rad_SAM PF01964.18 RLN58424.1 - 1.1 8.0 3.2 1.6 7.4 3.2 1.1 1 0 0 1 1 1 0 Radical SAM ThiC family T7SS_ESX_EspC PF10824.8 RLN58425.1 - 0.74 10.3 5.9 0.15 12.5 1.4 2.2 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm DUF3450 PF11932.8 RLN58426.1 - 5.9 6.1 50.5 0.44 9.8 7.0 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3450) DUF3584 PF12128.8 RLN58427.1 - 0.0034 15.0 16.3 0.0047 14.5 16.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Atg14 PF10186.9 RLN58427.1 - 0.007 15.5 9.4 0.007 15.5 9.4 2.4 1 1 1 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 WHAMM-JMY_N PF15920.5 RLN58427.1 - 0.033 14.0 0.0 0.09 12.6 0.0 1.7 2 0 0 2 2 2 0 N-terminal of Junction-mediating and WASP homolog-associated Phage_HK97_TLTM PF06120.11 RLN58427.1 - 0.11 11.7 12.5 0.22 10.7 12.3 1.5 1 1 0 1 1 1 0 Tail length tape measure protein DUF4407 PF14362.6 RLN58427.1 - 0.21 10.9 9.0 0.44 9.8 9.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 RLN58427.1 - 8.5 6.2 14.7 6.4 6.6 2.2 3.2 2 1 1 3 3 3 0 Septum formation initiator Sacchrp_dh_C PF16653.5 RLN58428.1 - 5.8e-86 288.9 0.0 9.3e-86 288.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 RLN58428.1 - 1e-28 100.3 0.0 2.4e-28 99.1 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 RLN58428.1 - 9e-18 64.8 0.5 2.2e-17 63.5 0.5 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Saccharop_dh_N PF04455.12 RLN58428.1 - 1.2e-10 41.7 0.1 2.7e-10 40.5 0.1 1.6 1 0 0 1 1 1 1 LOR/SDH bifunctional enzyme conserved region AlaDh_PNT_C PF01262.21 RLN58428.1 - 0.00011 21.6 0.0 0.038 13.3 0.0 2.8 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 RLN58428.1 - 0.17 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DYW_deaminase PF14432.6 RLN58429.1 - 8.9e-26 90.2 0.0 1.4e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 DYW family of nucleic acid deaminases Abhydrolase_1 PF00561.20 RLN58430.1 - 5.1e-05 23.1 0.0 0.0068 16.1 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN58430.1 - 0.001 19.7 6.1 0.0026 18.4 6.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 RLN58430.1 - 0.0013 18.6 0.0 0.16 11.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold PPR_3 PF13812.6 RLN58444.1 - 1.8e-05 24.7 0.0 0.0024 17.9 0.0 2.5 1 1 1 2 2 2 2 Pentatricopeptide repeat domain PPR_long PF17177.4 RLN58444.1 - 0.00011 21.7 0.1 0.00034 20.0 0.1 1.7 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 RLN58444.1 - 0.017 15.3 0.0 1.1 9.5 0.0 3.1 3 1 1 4 4 4 0 PPR repeat family PPR PF01535.20 RLN58444.1 - 0.12 12.7 0.0 29 5.2 0.0 3.2 3 0 0 3 3 3 0 PPR repeat OrfB_Zn_ribbon PF07282.11 RLN58447.1 - 1.8e-10 40.6 0.6 3.3e-10 39.8 0.6 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HTH_OrfB_IS605 PF12323.8 RLN58447.1 - 7.1e-09 35.0 2.2 7.1e-09 35.0 2.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Mu-like_Com PF10122.9 RLN58447.1 - 0.026 14.0 1.7 0.07 12.6 1.7 1.7 1 0 0 1 1 1 0 Mu-like prophage protein Com DNA_RNApol_7kD PF03604.13 RLN58447.1 - 0.058 13.1 4.5 0.057 13.1 2.2 2.1 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Pkinase PF00069.25 RLN58448.1 - 1.7e-46 158.7 0.0 2.4e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN58448.1 - 6.2e-40 137.1 0.0 8.5e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mid2 PF04478.12 RLN58448.1 - 0.0041 17.0 0.0 0.0082 16.0 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Pkinase_fungal PF17667.1 RLN58448.1 - 0.0068 15.2 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase LapA_dom PF06305.11 RLN58448.1 - 0.047 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain SKG6 PF08693.10 RLN58448.1 - 0.086 12.3 0.2 0.19 11.2 0.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Haspin_kinase PF12330.8 RLN58448.1 - 0.14 11.0 0.1 0.31 9.9 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_Tyr PF07714.17 RLN58449.1 - 1.2e-29 103.4 0.0 1.8e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN58449.1 - 2.5e-21 76.3 0.0 6e-16 58.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain stn_TNFRSF12A PF12191.8 RLN58449.1 - 0.083 13.1 0.1 0.21 11.8 0.1 1.8 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain CcmD PF04995.14 RLN58449.1 - 2.3 8.4 5.6 4.4 7.5 1.5 2.6 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Pkinase_Tyr PF07714.17 RLN58450.1 - 2e-29 102.7 0.0 6.3e-19 68.3 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 RLN58450.1 - 2.3e-23 82.9 0.0 8e-23 81.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RLN58450.1 - 0.022 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 RLN58451.1 - 6.3e-43 146.9 0.0 9.8e-42 143.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN58451.1 - 1.6e-41 142.4 0.0 1e-40 139.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain TMEM154 PF15102.6 RLN58451.1 - 0.00027 20.9 0.0 0.00064 19.7 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family CD34_antigen PF06365.12 RLN58451.1 - 0.0014 18.3 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 CD34/Podocalyxin family LapA_dom PF06305.11 RLN58451.1 - 0.0059 16.4 0.4 0.016 15.0 0.4 1.7 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain SIT PF15330.6 RLN58451.1 - 0.019 15.4 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF2970 PF11174.8 RLN58451.1 - 0.025 14.4 0.8 0.059 13.2 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) EphA2_TM PF14575.6 RLN58451.1 - 0.038 14.9 0.2 0.18 12.7 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 RLN58451.1 - 0.039 13.8 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Transmembrane protein 51 Pkinase_fungal PF17667.1 RLN58451.1 - 0.073 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TMEM100 PF16311.5 RLN58451.1 - 0.082 12.5 0.3 0.17 11.5 0.3 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 DAG1 PF05454.11 RLN58451.1 - 0.19 11.1 0.0 0.78 9.1 0.0 1.9 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) SRTM1 PF15872.5 RLN58451.1 - 0.9 9.7 5.6 0.23 11.6 0.4 2.6 2 1 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 Pkinase PF00069.25 RLN58452.1 - 9.4e-46 156.3 0.0 1.6e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN58452.1 - 6.7e-44 150.1 0.0 9.8e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase GspH PF12019.8 RLN58452.1 - 0.37 11.2 4.5 0.55 10.7 1.1 2.3 2 0 0 2 2 2 0 Type II transport protein GspH Mucin PF01456.17 RLN58455.1 - 0.0044 17.0 28.0 0.0076 16.2 28.0 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein MGC-24 PF05283.11 RLN58455.1 - 2.1 8.8 14.2 4.4 7.8 14.2 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Hamartin PF04388.12 RLN58455.1 - 2.5 6.7 5.6 2.9 6.4 5.6 1.1 1 0 0 1 1 1 0 Hamartin protein Kinesin PF00225.23 RLN58456.1 - 9.7e-101 337.0 0.0 1.7e-100 336.2 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN58456.1 - 4e-20 72.3 0.0 3e-19 69.4 0.0 2.3 1 1 0 1 1 1 1 Microtubule binding FAM60A PF15396.6 RLN58456.1 - 0.45 10.5 5.9 0.1 12.6 0.6 2.3 1 1 1 2 2 2 0 Protein Family FAM60A Pkinase_Tyr PF07714.17 RLN58457.1 - 1.8e-39 135.6 0.0 3.3e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN58457.1 - 6.7e-34 117.4 0.0 2.5e-33 115.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Arm PF00514.23 RLN58457.1 - 9.5e-11 41.4 0.2 0.011 15.8 0.0 3.9 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat DZR PF12773.7 RLN58457.1 - 5.9e-05 23.0 2.3 0.00025 21.0 1.0 2.5 2 0 0 2 2 2 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 RLN58457.1 - 0.00069 19.2 0.6 0.0019 17.9 0.6 1.8 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 RLN58457.1 - 0.015 16.0 0.4 0.061 14.1 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon family TackOD1 PF18551.1 RLN58457.1 - 0.048 13.3 0.5 0.16 11.7 0.2 2.0 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 Arm_2 PF04826.13 RLN58457.1 - 0.16 11.4 0.0 8.4 5.8 0.0 2.7 1 1 1 2 2 2 0 Armadillo-like zf-ribbon_3 PF13248.6 RLN58457.1 - 0.41 10.1 4.5 0.29 10.6 1.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain GAT PF03127.14 RLN58457.1 - 3.6 8.0 4.5 5.5 7.4 1.3 2.8 2 1 1 3 3 3 0 GAT domain ABC2_membrane PF01061.24 RLN58471.1 - 5.4e-37 127.3 27.5 5.4e-37 127.3 27.5 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RLN58471.1 - 3.7e-17 63.1 0.0 6.2e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN58471.1 - 1.2e-05 25.3 0.0 0.03 14.1 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system PDR_assoc PF08370.11 RLN58471.1 - 0.001 18.8 1.1 0.001 18.8 1.1 2.7 3 0 0 3 3 2 1 Plant PDR ABC transporter associated RsgA_GTPase PF03193.16 RLN58471.1 - 0.0013 18.7 0.1 0.0033 17.3 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 RLN58471.1 - 0.0014 17.9 25.4 0.0024 17.1 25.4 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 RLN58471.1 - 0.0042 16.8 1.3 0.013 15.2 1.3 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN58471.1 - 0.03 14.8 0.3 0.05 14.1 0.3 1.2 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 RLN58471.1 - 0.036 13.5 0.1 1.9 7.9 0.1 2.6 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RLN58471.1 - 0.053 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PDR_CDR PF06422.12 RLN58471.1 - 0.14 12.1 0.5 0.46 10.4 0.5 1.9 1 0 0 1 1 1 0 CDR ABC transporter AAA_25 PF13481.6 RLN58471.1 - 0.16 11.5 0.4 0.34 10.5 0.4 1.4 1 0 0 1 1 1 0 AAA domain DUF5090 PF17009.5 RLN58471.1 - 8.8 6.2 8.3 18 5.2 8.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) DAHP_synth_1 PF00793.20 RLN58502.1 - 1.3e-27 96.4 0.0 2.2e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 DAHP synthetase I family SLAC1 PF03595.17 RLN58502.1 - 0.023 14.0 0.1 0.031 13.5 0.1 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel MORN PF02493.20 RLN58503.1 - 5.6e-19 66.8 21.8 4.1e-06 26.4 0.2 7.0 8 0 0 8 8 8 5 MORN repeat FlgD_ig PF13860.6 RLN58503.1 - 0.013 15.3 1.2 2.1 8.2 0.4 3.1 3 0 0 3 3 3 0 FlgD Ig-like domain DUF4982 PF16355.5 RLN58503.1 - 0.25 11.3 2.2 11 6.1 0.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4982) Cwf_Cwc_15 PF04889.12 RLN58504.1 - 4.3e-52 177.3 24.2 5.3e-52 177.0 24.2 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 RLN58504.1 - 0.46 8.7 18.0 0.51 8.6 18.0 1.1 1 0 0 1 1 1 0 CDC45-like protein PA26 PF04636.13 RLN58504.1 - 0.72 8.7 6.0 0.77 8.6 6.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4407 PF14362.6 RLN58504.1 - 8 5.7 11.7 11 5.3 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pept_tRNA_hydro PF01195.19 RLN58505.1 - 4.3e-43 147.2 0.0 6.5e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase DUF4943 PF16301.5 RLN58505.1 - 0.084 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4943) Pro_isomerase PF00160.21 RLN58506.1 - 1.3e-46 158.8 0.0 1.3e-46 158.8 0.0 1.9 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YL1 PF05764.13 RLN58506.1 - 0.044 13.9 32.4 0.065 13.4 32.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein eIF3_subunit PF08597.10 RLN58506.1 - 0.2 11.5 26.7 0.27 11.1 26.7 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit LMBR1 PF04791.16 RLN58506.1 - 0.78 8.6 2.3 0.9 8.4 2.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CDC45 PF02724.14 RLN58506.1 - 1.5 7.0 22.0 2.1 6.5 22.0 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 RLN58506.1 - 2.2 8.0 15.8 3.1 7.5 15.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.8 RLN58506.1 - 5.8 5.7 23.2 9.1 5.1 23.2 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SLC12 PF03522.15 RLN58506.1 - 7.4 5.5 13.5 9.4 5.1 13.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 AAA_11 PF13086.6 RLN58506.1 - 8.5 6.1 15.7 11 5.6 15.7 1.2 1 0 0 1 1 1 0 AAA domain Rad60-SLD PF11976.8 RLN58507.1 - 8.7e-22 76.7 0.0 9.6e-07 28.6 0.0 3.7 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 RLN58507.1 - 9.3e-09 34.9 0.0 0.0066 16.2 0.0 3.5 3 0 0 3 3 3 2 Ubiquitin family PRP1_N PF06424.12 RLN58507.1 - 0.13 12.7 5.6 0.27 11.6 5.6 1.6 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal PAC1 PF16094.5 RLN58507.1 - 2.5 7.2 5.7 5.2 6.2 5.7 1.5 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Myc_N PF01056.18 RLN58507.1 - 2.9 7.7 14.2 1.1 9.0 8.4 2.1 1 1 1 2 2 2 0 Myc amino-terminal region BHD_2 PF10404.9 RLN58507.1 - 3.2 8.8 6.3 13 6.8 4.8 2.7 2 1 0 2 2 2 0 Rad4 beta-hairpin domain 2 Spt5_N PF11942.8 RLN58507.1 - 5.1 8.1 14.7 20 6.2 9.3 2.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CENP-B_dimeris PF09026.10 RLN58507.1 - 8.8 6.8 14.9 23 5.4 8.3 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RRM_1 PF00076.22 RLN58508.1 - 7.5e-30 102.6 0.0 3.8e-14 52.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN58508.1 - 1.1e-06 28.7 0.0 0.0064 16.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 RLN58508.1 - 0.00014 21.8 0.0 0.4 10.7 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Ebola_NP PF05505.12 RLN58508.1 - 5.6 5.1 8.7 8.4 4.6 8.7 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein DUF3246 PF11596.8 RLN58508.1 - 9.8 5.5 10.2 19 4.6 10.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) TPR_19 PF14559.6 RLN58509.1 - 4.9e-07 30.2 25.6 4.1e-06 27.2 0.1 7.0 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 RLN58509.1 - 1.6e-06 28.4 16.1 0.34 11.6 0.0 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN58509.1 - 2.8e-06 27.5 32.9 0.0012 19.0 7.6 6.5 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 RLN58509.1 - 2.7e-05 23.9 8.0 0.52 10.5 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN58509.1 - 2.7e-05 23.9 26.3 0.02 15.0 0.1 7.7 8 0 0 8 8 7 3 Tetratricopeptide repeat Calici_MSP PF05752.11 RLN58509.1 - 0.00088 19.1 2.2 0.0019 18.0 2.2 1.5 1 0 0 1 1 1 1 Calicivirus minor structural protein TPR_8 PF13181.6 RLN58509.1 - 0.0015 18.6 4.0 0.14 12.4 0.0 4.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN58509.1 - 0.0047 16.7 5.2 8.4 6.4 0.1 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN58509.1 - 0.021 15.4 27.0 0.19 12.4 1.3 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN58509.1 - 0.025 14.9 1.3 0.025 14.9 1.3 5.7 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN58509.1 - 0.085 12.7 13.3 0.22 11.4 0.4 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Sec34 PF04136.15 RLN58509.1 - 1.4 8.8 8.4 0.68 9.8 5.2 2.2 2 0 0 2 2 2 0 Sec34-like family V_ATPase_I PF01496.19 RLN58509.1 - 4.1 5.2 7.3 6.8 4.5 7.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Far-17a_AIG1 PF04750.14 RLN58510.1 - 3.7e-05 23.1 8.4 3.7e-05 23.1 8.4 1.7 2 0 0 2 2 2 1 FAR-17a/AIG1-like protein GST_C PF00043.25 RLN58511.1 - 3.9e-07 30.2 0.5 8.4e-07 29.1 0.3 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RLN58511.1 - 5.4e-05 23.3 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RLN58511.1 - 6.8e-05 22.8 2.3 0.00014 21.8 2.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 RLN58511.1 - 0.0072 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RTC PF01137.21 RLN58512.1 - 1.7e-63 213.8 1.2 2.5e-63 213.3 1.2 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase TatD_DNase PF01026.21 RLN58512.1 - 2.1e-62 210.8 0.0 4.4e-62 209.7 0.0 1.5 2 0 0 2 2 2 1 TatD related DNase tRNA-synt_2b PF00587.25 RLN58513.1 - 1.1e-39 136.2 0.0 1.8e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 RLN58513.1 - 3.1e-18 65.7 0.1 7.6e-18 64.4 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 RLN58513.1 - 8.1e-09 35.5 0.0 1.7e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Kelch_3 PF13415.6 RLN58514.1 - 8.1e-31 105.7 14.7 1.6e-06 28.2 0.0 7.3 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN58514.1 - 2.8e-28 97.4 4.0 3.1e-05 23.9 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 RLN58514.1 - 6.3e-25 86.9 6.5 6.4e-07 29.3 0.0 6.0 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 RLN58514.1 - 1.9e-24 85.1 3.8 7.6e-07 29.2 0.0 5.7 4 1 2 6 6 6 5 Kelch motif Kelch_2 PF07646.15 RLN58514.1 - 8.7e-23 79.4 6.7 5.1e-06 26.2 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 RLN58514.1 - 1.4e-21 75.8 0.6 8.8e-06 25.2 0.0 6.0 6 0 0 6 6 6 3 Kelch motif RAG2 PF03089.14 RLN58514.1 - 0.023 13.7 0.0 7.2 5.5 0.0 3.6 4 0 0 4 4 4 0 Recombination activating protein 2 cNMP_binding PF00027.29 RLN58515.1 - 1.4e-15 57.1 0.0 0.00021 21.3 0.0 4.3 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain MIT_LIKE_ACTX PF17556.2 RLN58516.1 - 0.031 14.9 0.2 0.09 13.4 0.2 1.7 1 0 0 1 1 1 0 MIT-like atracotoxin family EF-hand_1 PF00036.32 RLN58578.1 - 2e-20 70.7 10.1 8.4e-07 28.1 0.3 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 RLN58578.1 - 4.3e-18 65.5 8.6 3.4e-12 46.6 0.4 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN58578.1 - 3.3e-15 54.8 13.3 0.00017 20.9 0.2 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 RLN58578.1 - 1.4e-14 52.7 10.0 6.2e-05 22.6 0.2 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 RLN58578.1 - 8.3e-12 44.8 10.5 2.1e-05 24.3 0.6 3.4 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RLN58578.1 - 2.5e-05 24.6 2.1 0.017 15.5 0.4 2.6 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RLN58578.1 - 0.00035 20.5 7.8 0.4 10.7 0.1 3.6 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 RLN58578.1 - 0.088 13.2 0.4 0.99 9.8 0.1 2.5 2 1 0 2 2 2 0 EF-hand domain EF-hand_14 PF17959.1 RLN58578.1 - 0.1 13.0 0.8 12 6.3 0.1 2.8 2 1 0 2 2 2 0 EF-hand domain DAP3 PF10236.9 RLN58579.1 - 5.7e-33 114.4 0.0 1.8e-32 112.8 0.0 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 RLN58579.1 - 0.0021 18.4 0.0 0.0049 17.3 0.0 1.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.7 RLN58579.1 - 0.074 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DUF2791 PF10923.8 RLN58579.1 - 0.092 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) VRR_NUC PF08774.11 RLN58580.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 VRR-NUC domain SNF2_N PF00176.23 RLN58581.1 - 2.1e-73 247.0 0.2 6e-73 245.6 0.2 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN58581.1 - 2.3e-18 66.5 0.0 7.4e-18 64.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.13 RLN58581.1 - 8.2e-12 45.3 5.4 8.2e-12 45.3 5.4 3.5 4 0 0 4 4 4 1 HSA ResIII PF04851.15 RLN58581.1 - 1.9e-10 41.0 0.1 1.2e-09 38.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RLN58581.1 - 1.2e-06 28.4 0.0 5e-06 26.4 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 RLN58581.1 - 0.00015 21.5 0.0 0.00047 19.9 0.0 1.8 1 0 0 1 1 1 1 SWI2/SNF2 ATPase SnAC PF14619.6 RLN58581.1 - 0.00022 21.7 0.1 0.00022 21.7 0.1 2.5 2 0 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex HDA2-3 PF11496.8 RLN58581.1 - 0.0014 17.8 0.0 0.015 14.5 0.0 2.6 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Gluconate_2-dh3 PF13618.6 RLN58581.1 - 0.26 11.5 3.8 1.4 9.2 0.6 3.3 2 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Pkinase_Tyr PF07714.17 RLN58582.1 - 0.075 12.3 0.1 0.075 12.3 0.1 1.4 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.25 RLN58582.1 - 0.14 11.5 0.2 0.23 10.8 0.2 1.3 1 0 0 1 1 1 0 Protein kinase domain M20_dimer PF07687.14 RLN58598.1 - 1.1e-17 63.9 0.0 1.9e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 RLN58598.1 - 1.2e-16 61.1 0.0 2.7e-16 59.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Amidohydro_1 PF01979.20 RLN58599.1 - 4.5e-27 95.3 0.1 2.5e-23 83.0 0.1 2.1 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 RLN58599.1 - 0.00013 21.6 0.6 0.26 10.7 0.1 3.0 2 1 1 3 3 3 2 Amidohydrolase family NAD_binding_1 PF00175.21 RLN58600.1 - 4.6e-09 36.9 0.0 1.9e-08 34.9 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 RLN58600.1 - 1.2e-08 35.2 0.0 2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.22 RLN58600.1 - 1.8e-08 34.9 0.0 2.9e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Globin NAD_binding_6 PF08030.12 RLN58600.1 - 0.021 15.0 0.0 0.091 12.9 0.0 2.0 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Pkinase PF00069.25 RLN58601.1 - 1e-65 221.7 0.0 1.2e-65 221.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN58601.1 - 3.9e-29 101.7 0.0 5.3e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN58601.1 - 9.4e-05 21.9 0.1 0.00024 20.5 0.1 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 RLN58601.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN58601.1 - 0.14 11.0 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain DAO PF01266.24 RLN58602.1 - 1.5e-28 100.5 0.0 1.5e-27 97.2 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 RLN58602.1 - 2.8e-07 30.0 0.0 0.0052 15.9 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 RLN58602.1 - 0.00099 18.4 0.0 0.0038 16.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RLN58602.1 - 0.0038 17.4 0.0 0.041 14.1 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 RLN58602.1 - 0.012 14.8 1.3 0.073 12.1 1.3 2.0 1 1 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 RLN58602.1 - 0.015 14.5 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 RLN58602.1 - 0.022 14.0 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 RLN58602.1 - 0.039 14.0 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 RLN58602.1 - 0.083 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GlcNAc PF11397.8 RLN58603.1 - 1.1e-70 238.9 0.2 1.6e-59 202.1 0.1 2.1 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) 2OG-FeII_Oxy_3 PF13640.6 RLN58603.1 - 4.6e-12 46.7 0.0 1.1e-11 45.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 RLN58603.1 - 3.3e-08 34.1 0.0 8.4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF883 PF05957.13 RLN58604.1 - 6.2 7.5 12.8 2.5 8.8 6.3 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) YL1 PF05764.13 RLN58604.1 - 8.6 6.4 28.4 0.6 10.2 7.3 3.2 2 1 1 3 3 3 0 YL1 nuclear protein Pkinase PF00069.25 RLN58605.1 - 2.1e-43 148.6 0.1 2.5e-20 72.9 0.0 2.7 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN58605.1 - 1.9e-11 43.7 0.2 2e-06 27.3 0.2 2.7 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 RLN58605.1 - 0.0092 15.9 7.8 4.5 7.1 0.0 4.1 3 0 0 3 3 3 2 Phosphotransferase enzyme family EF-hand_9 PF14658.6 RLN58605.1 - 0.022 15.1 0.0 0.06 13.7 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 RLN58605.1 - 0.023 15.1 0.2 0.023 15.1 0.2 2.6 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_6 PF13405.6 RLN58605.1 - 0.051 13.5 0.0 1.5 8.9 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 RLN58605.1 - 0.11 12.1 0.0 29 4.5 0.0 2.9 2 0 0 2 2 2 0 EF hand K_channel_TID PF07941.11 RLN58605.1 - 5.9 7.4 11.1 28 5.2 11.1 2.2 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF4596 PF15363.6 RLN58620.1 - 1.5 9.1 4.0 1.6 9.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) SNF2_N PF00176.23 RLN58630.1 - 8.8e-54 182.5 0.0 2.5e-53 181.0 0.0 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain DUF3535 PF12054.8 RLN58630.1 - 7.8e-17 61.6 0.6 9.1e-16 58.1 0.1 2.8 2 2 0 2 2 2 1 Domain of unknown function (DUF3535) Helicase_C PF00271.31 RLN58630.1 - 1.6e-16 60.6 0.0 1.1e-14 54.7 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN58630.1 - 3.9e-06 27.0 0.0 2e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RLN58630.1 - 0.00044 20.1 0.0 0.0017 18.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase CLASP_N PF12348.8 RLN58630.1 - 0.069 12.7 0.2 0.3 10.6 0.1 1.9 1 1 0 2 2 2 0 CLASP N terminal UpxZ PF06603.11 RLN58630.1 - 0.086 13.1 0.1 1.5 9.1 0.0 2.6 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists SWI2_SNF2 PF18766.1 RLN58630.1 - 0.14 11.8 0.2 0.65 9.6 0.0 2.0 2 0 0 2 2 2 0 SWI2/SNF2 ATPase PX PF00787.24 RLN58632.1 - 0.098 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 PX domain DHHW PF14286.6 RLN58632.1 - 0.1 11.9 0.1 0.41 9.9 0.0 1.8 2 0 0 2 2 2 0 DHHW protein PAP2 PF01569.21 RLN58633.1 - 1.8e-14 53.7 17.3 4.6e-11 42.6 7.7 3.6 2 2 0 2 2 2 2 PAP2 superfamily NmrA PF05368.13 RLN58633.1 - 8.1e-11 41.9 0.0 1.2e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family DUF212 PF02681.14 RLN58633.1 - 2.4e-05 24.5 2.7 0.058 13.5 0.0 3.1 2 1 0 3 3 3 2 Divergent PAP2 family PAP2_3 PF14378.6 RLN58633.1 - 0.032 13.9 10.1 1.4 8.5 4.5 2.5 2 1 0 2 2 2 0 PAP2 superfamily ThrE PF06738.12 RLN58633.1 - 0.051 12.9 2.8 0.095 12.1 2.8 1.3 1 0 0 1 1 1 0 Putative threonine/serine exporter UbiA PF01040.18 RLN58633.1 - 7.6 5.7 11.7 0.026 13.8 1.7 2.0 3 0 0 3 3 3 0 UbiA prenyltransferase family PDZ_1 PF12812.7 RLN58634.1 - 6.1e-24 83.8 0.0 1.2e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 PDZ-like domain Trypsin_2 PF13365.6 RLN58634.1 - 2.4e-17 64.2 0.0 9e-17 62.4 0.0 1.9 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_6 PF17820.1 RLN58634.1 - 1.7e-05 24.6 0.0 0.033 14.0 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 RLN58634.1 - 0.0001 22.5 0.0 0.0024 18.1 0.0 2.5 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 RLN58634.1 - 0.016 13.9 0.5 0.032 12.9 0.1 1.6 2 0 0 2 2 2 0 Peptidase S46 DUF31 PF01732.16 RLN58634.1 - 0.042 13.4 0.2 0.059 12.9 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Trypsin PF00089.26 RLN58634.1 - 0.1 12.4 0.0 0.35 10.7 0.0 1.8 1 1 0 1 1 1 0 Trypsin Peptidase_S7 PF00949.21 RLN58634.1 - 0.23 11.3 0.2 0.45 10.3 0.2 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease RNA_pol_Rpc4 PF05132.14 RLN58635.1 - 6.7 7.1 9.8 1.8 9.0 0.4 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 SH3_9 PF14604.6 RLN58636.1 - 2.5e-21 75.2 1.6 5.1e-10 39.1 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 RLN58636.1 - 3.1e-19 68.3 0.9 7.1e-09 35.1 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 RLN58636.1 - 4.2e-19 68.0 0.2 2.1e-10 40.1 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 RLN58636.1 - 2.4e-06 27.7 1.7 0.021 15.1 0.1 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain DZR PF12773.7 RLN58636.1 - 5.9e-05 23.0 7.0 0.00031 20.7 1.9 3.1 3 0 0 3 3 3 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 RLN58636.1 - 0.0015 18.2 2.7 0.0015 18.2 2.7 1.8 2 0 0 2 2 2 1 zinc-ribbon domain DUF5599 PF18141.1 RLN58636.1 - 0.025 14.8 0.0 8.4 6.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5599) zinc_ribbon_15 PF17032.5 RLN58636.1 - 0.11 13.3 8.9 0.13 13.0 2.4 2.8 3 0 0 3 3 3 0 zinc-ribbon family Nudix_N_2 PF14803.6 RLN58636.1 - 0.64 10.0 6.7 8.7 6.4 0.2 3.3 3 0 0 3 3 3 0 Nudix N-terminal ERM PF00769.19 RLN58636.1 - 1.1 9.0 24.4 2 8.2 24.4 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family zf-RanBP PF00641.18 RLN58636.1 - 2.6 7.4 11.9 0.16 11.4 5.7 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others XRN_M PF17846.1 RLN58636.1 - 5.5 5.8 6.7 8.2 5.3 6.7 1.2 1 0 0 1 1 1 0 Xrn1 helical domain BAF1_ABF1 PF04684.13 RLN58636.1 - 6.3 5.7 9.9 9.3 5.2 9.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Med3 PF11593.8 RLN58636.1 - 6.7 5.8 11.1 11 5.1 11.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Presenilin PF01080.17 RLN58636.1 - 8.3 5.1 6.1 13 4.4 6.1 1.3 1 0 0 1 1 1 0 Presenilin Meth_synt_2 PF01717.18 RLN58648.1 - 2.7e-51 174.8 0.1 3e-51 174.6 0.1 1.0 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Elicitin PF00964.17 RLN58649.1 - 4.3e-05 23.5 0.7 4.3e-05 23.5 0.7 2.0 2 0 0 2 2 2 1 Elicitin UPF0016 PF01169.19 RLN58650.1 - 1e-40 137.9 24.7 2.8e-22 78.8 5.8 3.0 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 EF-hand_1 PF00036.32 RLN58650.1 - 0.00098 18.5 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 RLN58650.1 - 0.0028 17.1 0.0 0.0055 16.1 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 RLN58650.1 - 0.023 15.1 0.0 0.04 14.4 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 RLN58650.1 - 0.044 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain RIH_assoc PF08454.11 RLN58651.1 - 7.4e-23 80.3 0.4 7.4e-23 80.3 0.4 3.9 4 1 0 4 4 4 1 RyR and IP3R Homology associated Ion_trans PF00520.31 RLN58651.1 - 1.9e-15 56.8 3.7 6.8e-15 55.0 3.7 2.0 1 0 0 1 1 1 1 Ion transport protein RYDR_ITPR PF01365.21 RLN58651.1 - 4.5e-14 52.3 0.2 1.5e-12 47.3 0.0 3.3 3 0 0 3 3 3 1 RIH domain Cons_hypoth95 PF03602.15 RLN58651.1 - 0.033 13.8 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MIG-14_Wnt-bd PF06664.12 RLN58651.1 - 0.27 10.4 7.5 1.1 8.4 2.8 2.7 2 1 0 2 2 2 0 Wnt-binding factor required for Wnt secretion HR1 PF02185.16 RLN58655.1 - 2.1 8.5 9.1 0.37 10.9 4.1 2.4 3 1 0 3 3 3 0 Hr1 repeat SWIRM-assoc_1 PF16495.5 RLN58655.1 - 8.2 6.5 8.5 0.33 11.0 1.9 2.0 2 0 0 2 2 2 0 SWIRM-associated region 1 Bro-N PF02498.17 RLN58670.1 - 0.00031 21.4 0.1 0.0025 18.4 0.0 2.3 2 0 0 2 2 2 1 BRO family, N-terminal domain Golgin_A5 PF09787.9 RLN58670.1 - 0.016 14.7 5.9 0.021 14.3 5.9 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 LCM PF04072.14 RLN58672.1 - 7.6e-42 143.4 0.5 1.3e-41 142.7 0.1 1.6 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Exo_endo_phos PF03372.23 RLN58690.1 - 2.9e-08 33.5 0.0 7.4e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.16 RLN58690.1 - 4e-08 32.6 22.3 7.2e-08 31.7 22.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 RLN58690.1 - 1.1e-06 28.4 8.9 2.6e-06 27.2 8.9 1.5 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 TPR_1 PF00515.28 RLN58690.1 - 0.008 16.0 8.1 0.22 11.4 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 RLN58690.1 - 0.041 14.0 7.2 0.32 11.2 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN58690.1 - 0.11 12.8 1.2 2.5 8.5 0.7 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PI3_PI4_kinase PF00454.27 RLN58691.1 - 5.3e-51 173.8 0.0 5e-36 124.8 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 RLN58691.1 - 1.1e-47 161.8 0.1 1.9e-47 161.1 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 RLN58691.1 - 1.3e-28 99.7 0.0 2.3e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 RLN58691.1 - 0.028 13.7 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) GAF PF01590.26 RLN58692.1 - 3e-08 34.4 0.0 1.5e-07 32.1 0.0 2.1 1 1 1 2 2 2 1 GAF domain GAF_3 PF13492.6 RLN58692.1 - 0.00075 19.8 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 GAF domain FYVE PF01363.21 RLN58692.1 - 0.0022 18.1 3.3 0.0042 17.2 3.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger Fer2_3 PF13085.6 RLN58692.1 - 0.16 12.0 0.4 0.49 10.4 0.4 1.8 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain PfkB PF00294.24 RLN58693.1 - 1.7e-22 80.1 0.2 1.3e-19 70.6 0.1 2.0 1 1 1 2 2 2 2 pfkB family carbohydrate kinase Patatin PF01734.22 RLN58694.1 - 2.7e-10 40.8 4.2 1.1e-07 32.3 4.2 2.5 1 1 0 1 1 1 1 Patatin-like phospholipase GlnD_UR_UTase PF08335.11 RLN58694.1 - 0.066 13.3 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase ABC_tran PF00005.27 RLN58696.1 - 1.2e-35 123.1 0.0 2.4e-35 122.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 RLN58696.1 - 2.1e-32 112.9 5.0 2.6e-32 112.6 5.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 RLN58696.1 - 1.8e-09 37.4 0.0 6.5e-07 29.0 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RLN58696.1 - 0.00053 20.4 1.0 0.0026 18.2 0.3 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 RLN58696.1 - 0.0013 18.5 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 RLN58696.1 - 0.0023 18.5 0.2 0.075 13.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 RLN58696.1 - 0.0039 16.5 0.0 0.009 15.3 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_21 PF13304.6 RLN58696.1 - 0.0043 16.9 0.5 0.028 14.2 0.1 2.1 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN58696.1 - 0.0058 16.3 0.1 0.015 15.0 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN58696.1 - 0.0086 16.4 0.1 0.037 14.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.17 RLN58696.1 - 0.011 15.9 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain DUF815 PF05673.13 RLN58696.1 - 0.017 14.3 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) G-alpha PF00503.20 RLN58696.1 - 0.019 14.1 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_24 PF13479.6 RLN58696.1 - 0.028 14.1 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 RLN58696.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_28 PF13521.6 RLN58696.1 - 0.12 12.7 1.5 0.61 10.3 0.2 2.7 2 1 1 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 RLN58696.1 - 0.14 12.2 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Pkinase_Tyr PF07714.17 RLN58721.1 - 7.3e-24 84.4 0.0 1.5e-16 60.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN58721.1 - 9.4e-23 80.9 0.0 8.1e-17 61.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain CTP_transf_1 PF01148.20 RLN58722.1 - 7.9e-06 25.8 17.7 2.3e-05 24.3 17.7 1.8 1 1 0 1 1 1 1 Cytidylyltransferase family Kelch_5 PF13854.6 RLN58722.1 - 0.13 12.3 4.2 0.46 10.5 0.2 3.5 3 0 0 3 3 3 0 Kelch motif HTH_Tnp_Tc5 PF03221.16 RLN58737.1 - 1.2e-07 31.6 0.0 4.6e-07 29.8 0.0 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 RLN58737.1 - 7e-05 22.6 0.1 0.00018 21.2 0.1 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease SARG PF15385.6 RLN58737.1 - 0.071 12.3 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein PI3_PI4_kinase PF00454.27 RLN58738.1 - 1.7e-44 152.5 0.0 3.3e-44 151.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 RLN58738.1 - 0.0072 16.7 2.3 0.33 11.4 0.4 3.2 2 1 0 2 2 2 1 FKBP12-rapamycin binding domain Myotub-related PF06602.14 RLN58738.1 - 0.17 10.8 0.8 0.34 9.8 0.8 1.4 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain ERM PF00769.19 RLN58738.1 - 0.42 10.4 8.7 0.2 11.5 2.9 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF2536 PF10750.9 RLN58760.1 - 6.7 6.7 11.2 0.84 9.6 1.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2536) AAA_25 PF13481.6 RLN58776.1 - 0.014 15.0 0.1 0.08 12.5 0.0 2.2 3 0 0 3 3 3 0 AAA domain Y_phosphatase PF00102.27 RLN58776.1 - 0.054 13.0 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase NACHT PF05729.12 RLN58776.1 - 0.18 11.7 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.7 RLN58776.1 - 0.23 10.3 0.0 0.52 9.2 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain Pkinase_Tyr PF07714.17 RLN58792.1 - 9.1e-46 156.2 0.0 1.2e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN58792.1 - 4.9e-44 150.7 0.0 6.6e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 RLN58792.1 - 0.0012 18.8 1.6 0.0035 17.3 0.5 2.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN58792.1 - 0.049 13.0 0.1 0.082 12.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RLN58792.1 - 0.13 11.2 0.0 0.31 9.9 0.1 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 RLN58792.1 - 0.21 10.4 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 RLN58793.1 - 2.8e-46 158.0 0.0 3.9e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN58793.1 - 3.9e-46 157.4 0.0 5.3e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN58793.1 - 0.018 15.0 1.9 0.14 12.1 0.0 2.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family MIOX PF05153.15 RLN58794.1 - 4.8e-41 141.0 0.1 7.1e-41 140.4 0.1 1.2 1 0 0 1 1 1 1 Myo-inositol oxygenase Acetyltransf_1 PF00583.25 RLN58794.1 - 1.1e-05 25.6 0.0 7.5e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Fascin PF06268.13 RLN58794.1 - 0.0001 22.5 0.0 0.023 14.9 0.0 2.3 1 1 1 2 2 2 2 Fascin domain Acetyltransf_7 PF13508.7 RLN58794.1 - 0.00026 21.3 0.0 0.0008 19.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RLN58794.1 - 0.00035 20.5 0.0 0.00071 19.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 RLN58794.1 - 0.0018 18.4 0.0 0.0039 17.3 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FRG1 PF06229.12 RLN58794.1 - 0.014 15.1 0.0 0.29 10.8 0.0 2.2 1 1 1 2 2 2 0 FRG1-like domain DUF569 PF04601.13 RLN58794.1 - 0.034 13.8 0.0 3.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF569) FR47 PF08445.10 RLN58794.1 - 0.091 12.7 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 FR47-like protein cNMP_binding PF00027.29 RLN58795.1 - 6.5e-34 115.9 3.3 4.9e-09 36.1 0.0 6.4 5 1 0 5 5 5 5 Cyclic nucleotide-binding domain Glyco_hydro_18 PF00704.28 RLN58796.1 - 9.3e-24 84.7 0.6 6.5e-22 78.6 0.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.13 RLN58796.1 - 0.053 12.9 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Abhydrolase_6 PF12697.7 RLN58798.1 - 1.7e-11 45.2 0.3 2.3e-11 44.7 0.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 RLN58798.1 - 2.6e-06 26.7 0.0 3.5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_1 PF00561.20 RLN58798.1 - 5.6e-06 26.2 0.0 0.037 13.7 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 RLN58798.1 - 5.4e-05 23.1 0.4 0.065 13.1 0.0 2.9 2 1 1 3 3 3 2 Serine hydrolase Hydrolase_4 PF12146.8 RLN58798.1 - 7.1e-05 22.2 0.1 0.00034 20.0 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 RLN58798.1 - 0.041 13.4 0.0 0.29 10.7 0.0 2.0 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 RLN58798.1 - 0.057 13.3 0.1 0.14 12.0 0.1 1.6 2 0 0 2 2 2 0 Lipase (class 3) Protoglobin PF11563.8 RLN58798.1 - 0.077 12.9 0.0 0.21 11.4 0.0 1.6 2 1 0 2 2 2 0 Protoglobin PAF-AH_p_II PF03403.13 RLN58798.1 - 0.14 10.7 0.1 0.21 10.1 0.1 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II FSH1 PF03959.13 RLN58798.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF1057 PF06342.12 RLN58799.1 - 2.3e-16 59.7 0.0 2.4e-15 56.4 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_6 PF12697.7 RLN58799.1 - 1.3e-12 48.8 0.4 1.9e-12 48.2 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN58799.1 - 1.5e-11 44.0 0.1 2.4e-11 43.4 0.1 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN58799.1 - 1.6e-11 44.3 0.3 6.2e-11 42.4 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 RLN58799.1 - 0.0042 17.0 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 RLN58799.1 - 0.0099 16.0 0.0 0.023 14.8 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 RLN58799.1 - 0.059 13.1 0.0 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein Ser_hydrolase PF06821.13 RLN58799.1 - 0.06 13.2 0.1 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase DDE_1 PF03184.19 RLN58800.1 - 1.2e-30 106.4 0.0 2.2e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_ABP1_N PF18107.1 RLN58800.1 - 1.2e-07 31.3 0.0 1.2e-07 31.3 0.0 2.5 3 0 0 3 3 3 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 RLN58800.1 - 1.6e-06 28.1 0.8 8e-06 25.8 0.0 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain Abhydrolase_6 PF12697.7 RLN58801.1 - 5.4e-16 59.9 2.1 8.7e-16 59.2 2.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 RLN58801.1 - 2.4e-14 53.1 0.0 2.3e-13 49.9 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_1 PF00561.20 RLN58801.1 - 2.1e-11 43.9 0.0 2.1e-08 34.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN58801.1 - 7.4e-09 35.2 0.0 1.7e-08 34.0 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 RLN58801.1 - 7.3e-05 23.0 0.1 0.00015 21.9 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain LIDHydrolase PF10230.9 RLN58801.1 - 0.00065 19.3 0.0 0.015 14.8 0.0 2.1 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 RLN58801.1 - 0.0013 18.6 0.3 0.25 11.2 0.1 2.3 2 0 0 2 2 2 2 Serine hydrolase PGAP1 PF07819.13 RLN58801.1 - 0.11 12.2 0.0 5.6 6.6 0.0 2.5 3 0 0 3 3 3 0 PGAP1-like protein Lipase_3 PF01764.25 RLN58801.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) FSH1 PF03959.13 RLN58801.1 - 0.22 11.2 0.0 0.73 9.5 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) VATC PF18716.1 RLN58802.1 - 1.9e-17 62.8 3.9 3.8e-17 61.9 3.9 1.5 1 0 0 1 1 1 1 Vms1-associating treble clef domain PTE PF02126.18 RLN58802.1 - 3e-09 36.7 0.0 3e-08 33.5 0.0 2.5 1 1 0 1 1 1 1 Phosphotriesterase family Aminotran_3 PF00202.21 RLN58803.1 - 2.2e-50 171.5 0.0 7.9e-49 166.4 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.6 RLN58803.1 - 6.4e-19 68.6 0.0 1.2e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain WW PF00397.26 RLN58804.1 - 4.1e-06 26.8 1.9 8.7e-06 25.7 1.9 1.6 1 0 0 1 1 1 1 WW domain FAIM1 PF06905.13 RLN58804.1 - 0.0043 16.8 0.2 0.011 15.4 0.1 1.7 2 0 0 2 2 2 1 Fas apoptotic inhibitory molecule (FAIM1) Mob1_phocein PF03637.17 RLN58805.1 - 7.8e-60 201.7 0.1 9.6e-60 201.4 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family FH2 PF02181.23 RLN58806.1 - 4.4e-31 108.3 10.7 5.1e-19 68.6 2.1 3.1 2 1 1 3 3 3 2 Formin Homology 2 Domain CCDC53 PF10152.9 RLN58806.1 - 8.5e-13 49.0 0.8 4.4e-06 27.2 0.0 3.5 3 0 0 3 3 3 2 Subunit CCDC53 of WASH complex FadA PF09403.10 RLN58806.1 - 0.24 11.9 8.3 0.12 12.8 4.0 2.7 3 0 0 3 3 3 0 Adhesion protein FadA Myosin_head PF00063.21 RLN58807.1 - 8e-103 344.9 0.2 8.9e-103 344.8 0.2 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_19 PF13245.6 RLN58807.1 - 0.0013 19.0 0.3 0.0023 18.3 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RLN58807.1 - 0.0054 17.0 0.0 0.016 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RLN58807.1 - 0.018 15.4 1.9 0.031 14.7 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain ATPase PF06745.13 RLN58807.1 - 0.039 13.3 0.1 2.5 7.4 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_29 PF13555.6 RLN58807.1 - 0.074 12.8 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 RLN58807.1 - 0.094 13.3 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 RLN58807.1 - 0.099 11.9 0.8 0.35 10.1 0.0 2.0 2 0 0 2 2 2 0 6-phosphofructo-2-kinase ResIII PF04851.15 RLN58807.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit adh_short PF00106.25 RLN58821.1 - 4.2e-29 101.4 0.1 5.3e-29 101.1 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN58821.1 - 1.2e-20 74.1 0.1 1.6e-20 73.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN58821.1 - 7.2e-10 39.1 0.1 8.2e-10 38.9 0.1 1.1 1 0 0 1 1 1 1 KR domain Pyr_redox_3 PF13738.6 RLN58821.1 - 2.8e-05 23.5 0.0 3.3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 RLN58821.1 - 0.0004 20.6 0.1 0.00064 20.0 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 RLN58821.1 - 0.0023 17.5 0.2 0.0029 17.1 0.2 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 RLN58821.1 - 0.0074 16.2 0.1 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_C48 PF02902.19 RLN58838.1 - 8.4e-15 55.2 0.1 4.2e-14 52.9 0.1 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SWI2_SNF2 PF18766.1 RLN58839.1 - 1.9e-21 76.8 0.6 7.5e-17 61.7 2.3 2.3 2 0 0 2 2 2 2 SWI2/SNF2 ATPase ResIII PF04851.15 RLN58839.1 - 4.4e-16 59.4 0.2 1.8e-15 57.3 0.1 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit WW PF00397.26 RLN58839.1 - 9.7e-11 41.6 0.3 1.7e-10 40.8 0.3 1.5 1 0 0 1 1 1 1 WW domain DEAD PF00270.29 RLN58839.1 - 6.3e-09 35.8 0.4 1.4e-08 34.7 0.4 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RLN58839.1 - 0.18 12.1 1.0 2.5 8.4 1.0 2.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 RLN58839.1 - 0.29 11.6 3.5 2.4 8.6 1.0 3.2 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) DENN PF02141.21 RLN58840.1 - 1.1e-15 58.0 0.1 1.6e-15 57.6 0.1 1.2 1 0 0 1 1 1 1 DENN (AEX-3) domain Arg_repressor PF01316.21 RLN58840.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Ead_Ea22 PF13935.6 RLN58840.1 - 0.09 13.4 0.1 0.13 12.9 0.1 1.2 1 0 0 1 1 1 0 Ead/Ea22-like protein CLZ PF16526.5 RLN58840.1 - 0.16 12.4 0.4 0.37 11.2 0.0 1.8 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ECH_1 PF00378.20 RLN58851.1 - 1.6e-35 122.7 2.6 4.1e-31 108.2 0.1 2.7 1 1 2 3 3 3 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RLN58851.1 - 0.033 13.7 0.0 0.063 12.8 0.0 1.4 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 RLN58852.1 - 1.8e-42 145.4 1.4 6.3e-38 130.5 0.1 2.5 3 0 0 3 3 3 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RLN58852.1 - 1.8e-08 34.3 0.1 4.3e-08 33.0 0.0 1.5 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Semialdhyde_dhC PF02774.18 RLN58854.1 - 5e-47 160.4 0.0 6.9e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 RLN58854.1 - 1.4e-25 90.1 0.0 3.6e-25 88.7 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 RLN58854.1 - 0.011 16.2 0.1 0.026 15.1 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent LRR_4 PF12799.7 RLN58855.1 - 8.4e-11 41.9 5.7 3.1e-05 24.3 0.5 3.1 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN58855.1 - 2.5e-08 33.5 7.1 0.0011 18.7 0.3 3.1 3 0 0 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 RLN58855.1 - 1e-06 28.4 1.7 2.7e-06 27.0 1.4 1.8 1 1 1 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 RLN58855.1 - 0.028 14.9 3.0 89 4.3 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 RLN58855.1 - 0.079 13.1 0.2 53 4.2 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich repeat DEAD PF00270.29 RLN58856.1 - 3.8e-50 170.1 0.0 5.3e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN58856.1 - 4.9e-31 107.4 0.0 1.7e-30 105.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN58856.1 - 0.028 14.4 0.0 0.058 13.4 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Beta_elim_lyase PF01212.21 RLN58857.1 - 6.1e-71 239.1 0.1 5.3e-56 190.1 0.0 2.0 1 1 1 2 2 2 2 Beta-eliminating lyase Aminotran_1_2 PF00155.21 RLN58857.1 - 5.4e-05 22.5 0.0 6.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 RLN58857.1 - 0.042 12.8 0.0 0.11 11.4 0.0 1.6 1 1 1 2 2 2 0 Aminotransferase class-V Pyridoxal_deC PF00282.19 RLN58857.1 - 0.12 11.1 0.0 0.4 9.3 0.0 1.6 1 1 1 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain RabGAP-TBC PF00566.18 RLN58937.1 - 3.3e-59 200.2 0.0 4.4e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DNA_pol3_delt_C PF14840.6 RLN58937.1 - 0.029 14.7 0.0 0.065 13.6 0.0 1.5 1 0 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term 7TMR-DISM_7TM PF07695.11 RLN58937.1 - 0.17 11.7 3.2 0.3 10.9 3.2 1.4 1 0 0 1 1 1 0 7TM diverse intracellular signalling SNARE_assoc PF09335.11 RLN58938.1 - 2.6e-16 60.2 6.0 2.6e-16 60.2 6.0 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF21 PF01595.20 RLN58955.1 - 1.9e-33 115.6 1.0 3.2e-33 114.9 1.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain FEZ PF07763.13 RLN58955.1 - 0.014 15.1 0.3 0.027 14.2 0.3 1.4 1 0 0 1 1 1 0 FEZ-like protein CBS PF00571.28 RLN58955.1 - 0.03 14.8 2.6 3.7 8.1 0.1 3.5 3 1 0 3 3 3 0 CBS domain ParBc PF02195.18 RLN58956.1 - 1.6e-07 31.5 0.0 0.033 14.5 0.0 2.6 2 0 0 2 2 2 2 ParB-like nuclease domain DUF1015 PF06245.11 RLN58956.1 - 0.014 14.3 0.1 4.7 6.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1015) DUF883 PF05957.13 RLN58956.1 - 1.1 9.9 5.0 0.64 10.7 0.9 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Peptidase_A22B PF04258.13 RLN58957.1 - 8.8e-87 291.2 8.0 1.2e-86 290.7 8.0 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 RLN58957.1 - 5.7e-05 22.7 1.7 5.7e-05 22.7 1.7 3.0 2 1 1 3 3 3 2 Signal-peptide peptidase, presenilin aspartyl protease PI3Ka PF00613.20 RLN58958.1 - 9.7e-07 28.4 0.3 1.8e-06 27.5 0.3 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF21 PF01595.20 RLN58959.1 - 1.6e-31 109.4 1.5 2.6e-31 108.7 1.5 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 RLN58959.1 - 7.5e-05 23.1 2.5 0.035 14.5 0.4 3.2 2 1 0 2 2 2 2 CBS domain Pkinase_Tyr PF07714.17 RLN58970.1 - 9.6e-36 123.4 0.0 1.4e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN58970.1 - 1.2e-25 90.3 0.0 1.9e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain NAM-associated PF14303.6 RLN58971.1 - 7.3e-10 39.8 5.2 5.4e-09 37.0 0.9 3.3 2 1 0 2 2 2 1 No apical meristem-associated C-terminal domain Pkinase_Tyr PF07714.17 RLN58972.1 - 2.1e-10 40.3 0.1 2.4e-10 40.1 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN58972.1 - 5.7e-08 32.4 0.0 7.1e-08 32.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN58973.1 - 1.4e-40 139.2 0.0 1.9e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN58973.1 - 3.8e-28 98.6 0.0 5.6e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 RLN59012.1 - 5e-14 52.2 0.2 3.1e-09 36.9 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN59012.1 - 0.00079 19.9 0.2 0.054 14.1 0.1 3.4 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN59012.1 - 0.0017 18.9 0.1 0.0051 17.4 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN59012.1 - 0.017 15.6 0.5 7.5 7.5 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat Ank PF00023.30 RLN59012.1 - 0.085 13.3 0.4 15 6.2 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat Sec1 PF00995.23 RLN59013.1 - 1e-102 345.3 0.0 1.2e-102 345.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family CRAL_TRIO PF00650.20 RLN59014.1 - 1.5e-17 63.8 0.0 2.5e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 RLN59014.1 - 0.042 14.0 0.1 0.075 13.2 0.1 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain ARD PF03079.14 RLN59014.1 - 0.49 10.6 0.0 0.49 10.6 0.0 3.4 2 1 2 4 4 4 0 ARD/ARD' family EF-hand_1 PF00036.32 RLN59015.1 - 0.056 13.0 2.6 0.074 12.6 0.9 2.0 1 1 1 2 2 2 0 EF hand EF-hand_6 PF13405.6 RLN59015.1 - 0.068 13.1 1.7 0.13 12.3 0.7 2.0 1 1 1 2 2 2 0 EF-hand domain LRR_8 PF13855.6 RLN59016.1 - 2.4e-52 174.5 48.6 1.5e-09 37.5 3.6 8.7 3 1 6 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 RLN59016.1 - 1e-36 124.3 42.8 2e-05 24.8 0.8 11.1 5 2 7 12 12 12 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN59016.1 - 6.7e-11 41.2 38.8 2.5 9.0 0.1 14.2 13 2 0 13 13 13 3 Leucine Rich Repeat LRR_9 PF14580.6 RLN59016.1 - 8.2e-09 35.2 14.4 0.0029 17.1 0.3 5.1 1 1 3 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.6 RLN59016.1 - 1.8e-05 24.4 47.0 1.6 8.9 0.3 13.3 14 0 0 14 14 14 4 Leucine Rich repeat Dpy-30 PF05186.13 RLN59017.1 - 2.1e-11 43.3 0.1 4.2e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 Dpy-30 motif DAGK_cat PF00781.24 RLN59017.1 - 0.1 12.2 0.0 0.29 10.8 0.0 1.8 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain DLH PF01738.18 RLN59018.1 - 1.8e-19 70.1 0.0 3.1e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family DASH_Dam1 PF08653.10 RLN59019.1 - 6e-10 38.8 0.1 2e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 DASH complex subunit Dam1 Halo_GVPC PF05465.13 RLN59019.1 - 0.11 12.8 0.4 0.19 12.0 0.4 1.3 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat PAP_assoc PF03828.19 RLN59020.1 - 7e-06 26.2 0.2 0.00011 22.4 0.1 2.5 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 RLN59020.1 - 5.8e-05 23.3 0.0 0.00014 22.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF1664 PF07889.12 RLN59020.1 - 0.034 14.2 1.3 0.067 13.2 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SlyX PF04102.12 RLN59020.1 - 0.039 14.6 4.3 0.12 13.0 4.3 1.9 1 0 0 1 1 1 0 SlyX GREB1 PF15782.5 RLN59020.1 - 4.2 4.4 8.1 7.9 3.4 8.1 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Mob1_phocein PF03637.17 RLN59021.1 - 9.5e-06 25.7 0.0 0.0004 20.4 0.1 2.1 2 0 0 2 2 2 1 Mob1/phocein family DUF3943 PF13084.6 RLN59021.1 - 0.056 13.3 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3943) GCFC PF07842.12 RLN59021.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.3 1 1 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein PIP5K PF01504.18 RLN59022.1 - 3.7e-40 137.9 0.3 1.5e-29 103.1 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 RLN59022.1 - 9.7e-25 87.1 0.5 1.8e-24 86.2 0.5 1.4 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 RLN59022.1 - 2.4e-14 53.2 15.1 2.4e-14 53.2 15.1 2.2 2 0 0 2 2 2 1 FYVE zinc finger PDZ_6 PF17820.1 RLN59022.1 - 4.8e-06 26.3 0.1 1.6e-05 24.7 0.1 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RLN59022.1 - 0.00029 21.1 0.0 0.00082 19.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain SOAR PF16533.5 RLN59022.1 - 0.22 11.5 1.0 0.88 9.6 1.0 2.1 1 0 0 1 1 1 0 STIM1 Orai1-activating region E1-E2_ATPase PF00122.20 RLN59034.1 - 3.1e-31 108.3 2.0 3.5e-31 108.1 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 RLN59034.1 - 1.6e-07 31.8 0.0 7.1e-05 23.2 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN59034.1 - 0.0012 18.9 0.1 0.0032 17.5 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 RLN59034.1 - 0.11 12.2 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus FeoB_Cyto PF17910.1 RLN59042.1 - 0.02 15.4 0.7 0.12 12.9 0.3 2.1 2 0 0 2 2 2 0 FeoB cytosolic helical domain JHBP PF06585.11 RLN59042.1 - 0.024 13.8 0.2 0.042 13.0 0.2 1.3 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) DUF948 PF06103.11 RLN59042.1 - 0.076 13.3 0.8 4.3 7.7 0.2 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Dimer_Tnp_hAT PF05699.14 RLN59068.1 - 4.5e-10 39.2 0.0 8.1e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF1180 PF06679.12 RLN59144.1 - 0.012 16.1 1.4 0.016 15.6 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) TMEM100 PF16311.5 RLN59144.1 - 0.013 15.1 0.1 0.031 13.9 0.1 1.6 1 0 0 1 1 1 0 Transmembrane protein 100 EphA2_TM PF14575.6 RLN59144.1 - 0.08 13.8 0.0 0.2 12.6 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2681 PF10883.8 RLN59144.1 - 0.081 13.3 0.4 0.15 12.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF4381 PF14316.6 RLN59144.1 - 0.081 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PgaD PF13994.6 RLN59144.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 PgaD-like protein SCF PF02404.15 RLN59145.1 - 0.066 12.5 0.4 0.1 12.0 0.1 1.5 2 0 0 2 2 2 0 Stem cell factor DUF1180 PF06679.12 RLN59145.1 - 0.068 13.6 0.1 0.095 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Cytochrom_C PF00034.21 RLN59147.1 - 6.8e-16 59.2 0.3 9.9e-16 58.7 0.3 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 RLN59147.1 - 5e-07 29.9 3.2 3e-06 27.4 3.2 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 RLN59147.1 - 0.0026 17.5 0.5 0.0055 16.4 0.3 1.7 2 0 0 2 2 2 1 Cytochrome c-550 domain Brix PF04427.18 RLN59148.1 - 2.8e-26 92.8 0.5 5.3e-26 91.9 0.5 1.4 1 0 0 1 1 1 1 Brix domain Suf PF05843.14 RLN59148.1 - 0.00057 20.0 1.1 0.00097 19.2 1.1 1.3 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) eIF3g PF12353.8 RLN59148.1 - 0.068 13.6 1.7 0.16 12.4 1.7 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G RRP14 PF15459.6 RLN59148.1 - 4.2 8.1 8.5 4.2 8.0 0.1 2.7 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 stn_TNFRSF12A PF12191.8 RLN59149.1 - 0.023 14.9 0.7 0.047 13.9 0.1 1.8 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Bacillus_HBL PF05791.11 RLN59149.1 - 0.039 13.8 5.1 0.066 13.0 5.1 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF3134 PF11332.8 RLN59149.1 - 0.043 14.1 0.1 0.18 12.2 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) Kinesin_assoc PF16183.5 RLN59149.1 - 0.055 13.6 0.1 0.055 13.6 0.1 2.0 1 1 0 2 2 2 0 Kinesin-associated Med9 PF07544.13 RLN59149.1 - 0.12 12.5 3.3 1 9.5 0.4 2.5 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TMPIT PF07851.13 RLN59149.1 - 1.3 8.2 5.1 2 7.6 5.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein AMP-binding PF00501.28 RLN59169.1 - 8e-78 261.9 0.0 1e-77 261.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cas_Cas2CT1978 PF09707.10 RLN59169.1 - 1.2e-05 25.3 0.0 0.00033 20.6 0.0 3.2 5 0 0 5 5 5 1 CRISPR-associated protein (Cas_Cas2CT1978) LSM PF01423.22 RLN59192.1 - 3.5e-12 45.8 0.0 5.5e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RLN59192.1 - 0.00062 19.8 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain RhoGAP PF00620.27 RLN59193.1 - 1.8e-09 37.6 0.2 0.00072 19.4 0.0 2.6 2 0 0 2 2 2 2 RhoGAP domain DUF2277 PF10041.9 RLN59193.1 - 0.00096 19.4 0.1 0.0064 16.8 0.1 2.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2277) PH PF00169.29 RLN59193.1 - 0.0024 18.4 0.0 0.013 16.0 0.0 2.2 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN59193.1 - 0.0025 18.1 0.0 0.029 14.6 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain UPF0552 PF10574.9 RLN59193.1 - 0.0064 15.9 0.0 0.018 14.4 0.0 1.7 1 0 0 1 1 1 1 Arp2/3-interacting proteins Arpin Anoctamin PF04547.12 RLN59225.1 - 3.3e-58 197.6 18.7 4.2e-58 197.3 18.7 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel PUB_1 PF18486.1 RLN59225.1 - 0.075 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain BAR PF03114.18 RLN59226.1 - 0.0092 15.6 0.7 0.019 14.7 0.7 1.4 1 0 0 1 1 1 1 BAR domain CorA PF01544.18 RLN59227.1 - 1.1e-05 24.9 9.6 4.7e-05 22.8 9.6 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2951 PF11166.8 RLN59228.1 - 0.045 14.0 0.5 0.061 13.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Adhes-Ig_like PF09085.10 RLN59247.1 - 0.28 11.3 2.1 0.42 10.8 0.3 2.1 1 1 1 2 2 2 0 Adhesion molecule, immunoglobulin-like V_ATPase_I PF01496.19 RLN59247.1 - 0.9 7.4 13.6 1.2 7.0 13.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF966 PF06136.13 RLN59247.1 - 5.4 6.6 16.7 11 5.6 16.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Pkinase PF00069.25 RLN59248.1 - 3e-21 76.0 1.7 9.3e-21 74.4 1.7 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN59248.1 - 1.1e-10 41.3 0.4 1.6e-10 40.7 0.4 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Miga PF10265.9 RLN59248.1 - 0.1 11.5 0.1 0.12 11.4 0.1 1.1 1 0 0 1 1 1 0 Mitoguardin fn3 PF00041.21 RLN59249.1 - 9.8e-14 51.5 8.0 0.26 11.6 0.0 9.5 11 0 0 11 11 11 5 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RLN59249.1 - 1.4e-11 44.8 9.9 1.8 9.2 0.2 8.2 8 0 0 8 8 8 5 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 RLN59249.1 - 0.00097 19.5 1.8 0.89 10.0 0.0 5.1 7 0 0 7 7 7 1 Uncharacterised conserved protein (DUF2369) Mid1 PF12929.7 RLN59249.1 - 0.0017 17.7 0.6 2.4 7.3 0.0 3.5 4 0 0 4 4 4 2 Stretch-activated Ca2+-permeable channel component CPSase_L_D2 PF02786.17 RLN59250.1 - 2.8e-103 343.9 0.0 1.1e-78 263.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 RLN59250.1 - 8.7e-49 164.6 0.0 2e-48 163.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 RLN59250.1 - 1.6e-47 161.7 0.0 1.3e-46 158.8 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 RLN59250.1 - 2.3e-39 134.5 0.1 4.1e-39 133.7 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 RLN59250.1 - 4e-15 55.8 0.0 1.9e-14 53.6 0.0 2.2 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.22 RLN59250.1 - 8e-12 45.1 0.0 1.1e-07 31.6 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 RLN59250.1 - 1e-11 44.7 0.0 8.9e-05 22.2 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 RLN59250.1 - 4.8e-09 36.1 0.1 8.8e-05 22.1 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus Peptidase_C26 PF07722.13 RLN59250.1 - 5.2e-05 23.1 0.1 0.0063 16.3 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 RLN59250.1 - 0.00064 19.6 0.2 0.32 10.8 0.1 2.9 3 0 0 3 3 3 1 DJ-1/PfpI family RimK PF08443.11 RLN59250.1 - 0.0057 16.3 0.0 0.061 12.9 0.0 2.4 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 RLN59250.1 - 0.0096 16.0 0.1 2.5 8.1 0.0 3.1 3 0 0 3 3 3 1 ATP-grasp domain B12-binding PF02310.19 RLN59250.1 - 0.062 13.3 0.1 0.38 10.8 0.0 2.3 2 0 0 2 2 2 0 B12 binding domain TrkA_N PF02254.18 RLN59250.1 - 0.15 12.3 0.1 4.6 7.5 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain Ank_2 PF12796.7 RLN59251.1 - 2.6e-63 210.6 5.3 4.7e-17 62.3 0.1 4.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN59251.1 - 7.5e-41 138.0 3.7 2.1e-11 44.1 0.2 5.5 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 RLN59251.1 - 6.7e-40 133.8 3.1 1.4e-06 28.4 0.2 7.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 RLN59251.1 - 1.5e-37 127.1 10.0 1.4e-12 47.6 0.4 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN59251.1 - 6.4e-33 109.1 0.9 6.6e-05 23.0 0.0 7.4 7 0 0 7 7 7 7 Ankyrin repeat ABC2_membrane_3 PF12698.7 RLN59252.1 - 2.7e-17 62.9 34.7 1.9e-16 60.1 34.7 2.2 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 RLN59252.1 - 3.2e-08 34.2 0.6 6.3e-08 33.2 0.6 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 RLN59252.1 - 4.3e-05 23.0 30.4 0.0019 17.7 25.8 2.7 2 1 0 2 2 2 2 ABC-2 type transporter AAA_23 PF13476.6 RLN59252.1 - 0.002 18.7 0.6 0.0041 17.7 0.6 1.4 1 0 0 1 1 1 1 AAA domain ABC2_membrane_5 PF13346.6 RLN59252.1 - 0.0033 17.0 22.4 0.0074 15.9 22.4 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 RLN59252.1 - 0.0076 16.2 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN59252.1 - 0.01 15.6 0.3 0.027 14.2 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 RLN59252.1 - 0.073 12.8 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 RLN59252.1 - 0.2 11.4 0.3 0.34 10.7 0.3 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 RLN59252.1 - 0.23 11.2 0.0 1 9.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Pkinase_C PF00433.24 RLN59253.1 - 0.014 16.1 2.0 0.02 15.6 1.6 1.5 1 1 0 1 1 1 0 Protein kinase C terminal domain DUF5448 PF17526.2 RLN59253.1 - 0.054 13.7 0.0 0.07 13.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5448) HeLo PF14479.6 RLN59253.1 - 0.065 13.1 0.1 0.086 12.7 0.1 1.3 1 1 0 1 1 1 0 Prion-inhibition and propagation TSNAXIP1_N PF15739.5 RLN59276.1 - 0.022 15.1 0.5 0.061 13.7 0.5 1.7 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus tRNA_int_endo PF01974.17 RLN59276.1 - 0.56 10.3 1.9 28 4.9 0.1 2.7 2 0 0 2 2 2 0 tRNA intron endonuclease, catalytic C-terminal domain Late_protein_L2 PF00513.18 RLN59277.1 - 5.6 5.8 6.8 2 7.3 4.0 1.5 1 1 0 1 1 1 0 Late Protein L2 Kinesin PF00225.23 RLN59278.1 - 3.7e-118 394.2 0.0 9.4e-118 392.9 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN59278.1 - 3e-27 95.4 0.5 3.2e-26 92.1 0.0 2.6 3 0 0 3 3 3 1 Microtubule binding Kinesin_assoc PF16183.5 RLN59278.1 - 0.0036 17.5 3.5 0.0036 17.5 3.5 2.9 2 1 1 3 3 3 1 Kinesin-associated DUF812 PF05667.11 RLN59278.1 - 0.015 14.2 31.4 0.02 13.8 31.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Use1 PF09753.9 RLN59278.1 - 0.072 12.8 41.3 0.014 15.2 18.2 2.3 1 1 1 2 2 2 0 Membrane fusion protein Use1 AAA_22 PF13401.6 RLN59278.1 - 0.59 10.4 4.0 0.76 10.0 0.0 3.0 2 1 0 2 2 2 0 AAA domain Cupin_8 PF13621.6 RLN59278.1 - 5.3 6.7 7.8 2.2 7.9 2.0 2.3 1 1 1 2 2 2 0 Cupin-like domain Carbpep_Y_N PF05388.11 RLN59278.1 - 6 7.4 8.4 3.2 8.3 4.4 2.4 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide Leo1 PF04004.13 RLN59279.1 - 2e-36 125.3 1.0 2e-36 125.3 1.0 2.5 3 0 0 3 3 3 1 Leo1-like protein Bindin PF02084.15 RLN59279.1 - 4.7 7.4 11.0 0.32 11.2 1.2 2.4 2 0 0 2 2 2 0 Bindin AAA_16 PF13191.6 RLN59280.1 - 1.4e-07 32.1 0.0 6.5e-07 29.9 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RLN59280.1 - 0.00014 22.1 0.4 0.00058 20.1 0.1 2.3 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 RLN59280.1 - 0.00095 19.1 0.0 0.0023 17.9 0.0 1.7 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea T2SSE PF00437.20 RLN59280.1 - 0.0027 16.8 0.0 0.0051 15.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Rad17 PF03215.15 RLN59280.1 - 0.005 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain Viral_helicase1 PF01443.18 RLN59280.1 - 0.013 15.2 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 RLN59280.1 - 0.033 13.5 0.0 0.071 12.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Ank_2 PF12796.7 RLN59281.1 - 2.2e-38 130.7 2.8 4.9e-13 49.5 0.0 5.2 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN59281.1 - 9.2e-30 99.4 4.6 0.00014 22.0 0.1 9.5 8 1 1 9 9 9 5 Ankyrin repeat Ank_4 PF13637.6 RLN59281.1 - 1e-29 102.5 3.1 7.6e-10 39.1 0.1 6.6 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 RLN59281.1 - 2.7e-25 87.7 16.2 6.7e-07 29.5 1.4 8.0 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 RLN59281.1 - 9.9e-20 70.4 8.4 7.3e-07 29.3 0.0 7.1 4 2 5 9 9 9 4 Ankyrin repeats (many copies) FMN_red PF03358.15 RLN59302.1 - 0.0002 21.1 0.1 0.00032 20.5 0.1 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Mito_carr PF00153.27 RLN59303.1 - 7e-55 183.0 4.1 6.4e-19 67.7 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein MaoC_dehydratas PF01575.19 RLN59303.1 - 1.3e-29 102.3 0.0 2.9e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 RLN59303.1 - 3.7e-05 23.9 0.0 0.0012 18.9 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase EGF_2 PF07974.13 RLN59304.1 - 2e-10 40.8 45.2 1.8e-06 28.2 7.6 4.6 4 0 0 4 4 4 4 EGF-like domain EGF_Tenascin PF18720.1 RLN59304.1 - 0.012 15.6 7.1 0.012 15.6 7.1 4.8 5 0 0 5 5 5 0 Tenascin EGF domain EGF PF00008.27 RLN59304.1 - 0.031 14.6 3.0 0.031 14.6 3.0 4.7 4 0 0 4 4 4 0 EGF-like domain Laminin_EGF PF00053.24 RLN59304.1 - 5.9 7.1 37.8 3 8.1 11.4 3.9 2 1 1 3 3 3 0 Laminin EGF domain EGF PF00008.27 RLN59305.1 - 2.1e-06 27.9 16.7 0.00028 21.1 5.2 2.5 2 0 0 2 2 2 2 EGF-like domain EGF_2 PF07974.13 RLN59305.1 - 4.4e-06 27.0 29.3 0.00019 21.7 5.9 2.6 3 0 0 3 3 3 2 EGF-like domain EB PF01683.18 RLN59305.1 - 6.4e-05 23.2 14.3 0.022 15.0 5.1 2.1 2 0 0 2 2 2 2 EB module hEGF PF12661.7 RLN59305.1 - 0.00057 20.4 4.5 0.00057 20.4 4.5 3.3 4 0 0 4 4 4 1 Human growth factor-like EGF S_locus_glycop PF00954.20 RLN59305.1 - 0.5 10.9 10.1 2.7 8.6 1.4 2.2 2 0 0 2 2 2 0 S-locus glycoprotein domain cEGF PF12662.7 RLN59305.1 - 4.1 7.4 15.1 0.53 10.3 1.9 3.1 3 0 0 3 3 3 0 Complement Clr-like EGF-like Sec1 PF00995.23 RLN59306.1 - 1.3e-73 249.1 0.0 1.6e-73 248.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family ZnuA PF01297.17 RLN59306.1 - 0.097 12.1 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic PALP PF00291.25 RLN59307.1 - 5.7e-64 216.3 0.0 7.3e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 RLN59307.1 - 1.3e-15 57.6 0.6 4.3e-09 36.7 0.1 3.5 4 0 0 4 4 4 2 CBS domain DUF2475 PF10629.9 RLN59308.1 - 0.058 13.6 4.0 6.7 7.0 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2475) SPATA48 PF15073.6 RLN59308.1 - 0.27 11.5 1.9 0.49 10.7 0.1 2.4 3 1 0 3 3 3 0 Spermatogenesis-associated protein 48 PfkB PF00294.24 RLN59309.1 - 2.7e-66 223.9 1.1 3.4e-66 223.6 1.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase BT1 PF03092.16 RLN59320.1 - 6.1e-19 67.6 17.2 1.6e-14 53.1 1.8 3.3 3 0 0 3 3 3 3 BT1 family DUF5083 PF16890.5 RLN59320.1 - 1.3 8.8 5.9 4.2 7.1 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5083) DUF3810 PF12725.7 RLN59320.1 - 6.3 6.0 11.4 0.94 8.8 1.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) BT1 PF03092.16 RLN59321.1 - 7.7e-18 64.0 16.0 3.3e-13 48.7 1.2 3.2 3 0 0 3 3 3 3 BT1 family BT1 PF03092.16 RLN59322.1 - 3.4e-17 61.9 12.4 5.2e-12 44.8 0.8 3.3 3 0 0 3 3 3 3 BT1 family YajC PF02699.15 RLN59322.1 - 0.98 9.4 4.2 21 5.1 0.5 2.9 2 0 0 2 2 2 0 Preprotein translocase subunit DUF5083 PF16890.5 RLN59322.1 - 2.1 8.1 5.0 13 5.5 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5083) DUF3810 PF12725.7 RLN59322.1 - 3.1 7.1 7.6 4.5 6.5 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) BT1 PF03092.16 RLN59323.1 - 1.7e-17 62.9 8.5 3.4e-11 42.1 0.5 3.3 3 0 0 3 3 3 3 BT1 family BT1 PF03092.16 RLN59324.1 - 2.8e-19 68.8 10.6 3.2e-13 48.8 0.8 3.2 3 0 0 3 3 3 3 BT1 family DUF5083 PF16890.5 RLN59324.1 - 0.18 11.5 2.8 8.9 6.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5083) PUCC PF03209.15 RLN59324.1 - 0.45 9.5 10.7 6.2 5.7 10.7 2.5 1 1 0 1 1 1 0 PUCC protein BT1 PF03092.16 RLN59325.1 - 4.1e-21 74.8 17.4 4.2e-14 51.7 1.3 3.2 3 0 0 3 3 3 3 BT1 family DUF3810 PF12725.7 RLN59325.1 - 10 5.4 10.1 5.9 6.1 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Sugar_tr PF00083.24 RLN59346.1 - 2.9e-98 329.7 23.5 3.3e-98 329.5 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN59346.1 - 1.1e-22 80.4 38.2 3.2e-17 62.5 4.9 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily Hydrolase_4 PF12146.8 RLN59360.1 - 1.7e-71 240.3 0.0 2.1e-44 151.6 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN59360.1 - 1.5e-16 61.7 3.4 3.8e-11 44.0 0.2 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN59360.1 - 1.4e-08 34.7 1.3 0.022 14.4 0.1 4.1 3 1 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN59360.1 - 5.7e-08 32.5 0.9 0.021 14.3 0.0 4.1 3 1 1 4 4 4 3 Prolyl oligopeptidase family DLH PF01738.18 RLN59360.1 - 1.8e-07 30.9 0.0 0.13 11.8 0.0 3.1 3 0 0 3 3 3 2 Dienelactone hydrolase family FSH1 PF03959.13 RLN59360.1 - 0.0014 18.4 0.0 0.37 10.4 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 RLN59360.1 - 0.0078 16.0 0.3 38 4.0 0.0 4.4 5 0 0 5 5 5 0 Phospholipase/Carboxylesterase MetJ PF01340.20 RLN59360.1 - 0.056 13.4 0.1 17 5.5 0.0 2.9 3 0 0 3 3 3 0 Met Apo-repressor, MetJ Abhydrolase_9 PF10081.9 RLN59360.1 - 0.18 10.8 0.1 4.8 6.2 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family Lactamase_B PF00753.27 RLN59361.1 - 1.3e-10 41.6 0.6 4.3e-10 39.9 0.1 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily cNMP_binding PF00027.29 RLN59361.1 - 3.2e-08 33.5 0.0 0.19 11.8 0.0 4.2 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Lactamase_B_2 PF12706.7 RLN59361.1 - 8.7e-07 28.7 0.1 1.6e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Aquarius_N PF16399.5 RLN59362.1 - 1.9e-121 406.6 9.1 1.3e-69 235.2 0.0 2.1 2 0 0 2 2 2 2 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 RLN59362.1 - 7.7e-31 107.3 0.0 1.6e-30 106.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RLN59362.1 - 1.6e-28 100.2 0.1 2.1e-27 96.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RLN59362.1 - 2.8e-08 33.7 0.1 0.0026 17.5 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 RLN59362.1 - 1e-05 25.9 0.1 0.00096 19.5 0.0 3.5 4 0 0 4 4 4 1 AAA domain UvrD-helicase PF00580.21 RLN59362.1 - 0.00013 21.6 0.5 0.0018 17.9 0.0 2.7 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 RLN59362.1 - 0.00081 19.2 0.2 0.002 17.9 0.2 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 RLN59362.1 - 0.0022 18.3 0.2 0.02 15.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 RLN59362.1 - 0.0056 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 RLN59362.1 - 0.006 16.6 0.0 0.025 14.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 RLN59362.1 - 0.013 15.9 0.1 0.013 15.9 0.1 3.4 3 1 0 3 3 3 0 AAA ATPase domain AAA PF00004.29 RLN59362.1 - 0.02 15.3 0.0 0.2 12.1 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 RLN59362.1 - 0.024 14.2 0.1 0.084 12.4 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 RLN59362.1 - 0.067 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoH PF02562.16 RLN59362.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Cupin_7 PF12973.7 RLN59362.1 - 0.16 11.9 0.0 0.57 10.1 0.0 1.9 1 0 0 1 1 1 0 ChrR Cupin-like domain EF-hand_6 PF13405.6 RLN59363.1 - 0.00026 20.6 0.0 0.001 18.8 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 RLN59363.1 - 0.00035 20.4 0.4 0.00071 19.4 0.4 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN59363.1 - 0.0011 18.3 0.7 0.0022 17.4 0.7 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 RLN59363.1 - 0.0018 18.7 1.1 0.0035 17.8 1.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_10 PF14788.6 RLN59363.1 - 0.016 15.1 0.1 0.033 14.1 0.1 1.5 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 RLN59363.1 - 0.1 12.1 0.2 0.21 11.2 0.2 1.5 1 0 0 1 1 1 0 EF hand DUF4757 PF15949.5 RLN59363.1 - 0.46 10.9 6.7 0.13 12.7 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4757) Pex14_N PF04695.13 RLN59363.1 - 7.5 7.2 10.3 29 5.3 0.2 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hydrolase_4 PF12146.8 RLN59364.1 - 5e-41 140.5 0.0 5.9e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN59364.1 - 1.6e-11 45.2 0.5 2.1e-11 44.8 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN59364.1 - 6.7e-05 22.7 0.4 0.012 15.3 0.4 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN59364.1 - 0.0026 17.3 0.1 2.4 7.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 RLN59365.1 - 3.7e-42 144.2 0.0 4.9e-26 91.5 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN59365.1 - 1.3e-06 29.2 1.0 2e-06 28.6 1.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN59365.1 - 0.0039 16.9 4.5 1.4 8.5 0.1 3.5 3 1 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN59365.1 - 0.018 14.5 0.0 4.5 6.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 RLN59366.1 - 1.6e-42 145.4 0.1 1.3e-26 93.3 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN59366.1 - 2e-06 28.6 3.3 2.9e-06 28.0 3.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN59366.1 - 0.00023 20.9 1.3 0.72 9.5 0.2 3.2 3 0 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN59366.1 - 0.014 14.9 0.1 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ank_2 PF12796.7 RLN59367.1 - 1.8e-40 137.4 20.9 1.2e-07 32.2 0.2 7.0 3 1 6 9 9 9 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN59367.1 - 2e-35 120.4 32.2 0.00021 21.5 0.2 15.1 6 3 11 17 17 17 12 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN59367.1 - 3e-35 120.2 17.9 2.1e-06 28.1 0.1 10.8 7 5 4 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN59367.1 - 1e-17 62.4 13.1 3.9 8.4 0.0 14.1 13 3 3 16 16 16 3 Ankyrin repeat Ank PF00023.30 RLN59367.1 - 2e-05 24.8 4.4 65 4.2 0.0 9.1 6 2 1 7 7 7 0 Ankyrin repeat DUF5049 PF16468.5 RLN59367.1 - 7.1e-05 22.6 0.9 25 4.8 0.0 7.1 3 2 6 9 9 9 1 Domain of unknown function (DUF5049) Pkinase_Tyr PF07714.17 RLN59368.1 - 7.1e-16 58.3 0.0 1.1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN59368.1 - 4.3e-13 49.2 0.0 8.6e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kri1 PF05178.12 RLN59369.1 - 0.036 14.6 2.2 0.057 14.0 2.2 1.3 1 0 0 1 1 1 0 KRI1-like family ABC_tran PF00005.27 RLN59370.1 - 4.7e-46 156.7 0.0 2e-23 83.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 RLN59370.1 - 3e-23 82.8 31.7 7.8e-14 52.0 14.0 2.4 2 1 0 2 2 2 2 ABC transporter transmembrane region Dynamin_N PF00350.23 RLN59370.1 - 3.6e-06 27.1 0.1 0.015 15.3 0.0 2.4 2 0 0 2 2 2 2 Dynamin family AAA_16 PF13191.6 RLN59370.1 - 3.7e-06 27.4 0.2 0.008 16.6 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 RLN59370.1 - 5.1e-06 26.1 0.4 0.5 9.8 0.0 4.1 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RLN59370.1 - 2e-05 24.7 0.4 0.25 11.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 RLN59370.1 - 2.7e-05 24.4 0.4 0.11 12.7 0.1 3.7 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 RLN59370.1 - 3.9e-05 23.3 2.2 0.13 12.0 0.1 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN59370.1 - 5.7e-05 23.4 1.7 0.82 9.9 0.2 3.5 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 RLN59370.1 - 7.2e-05 22.8 3.9 0.039 13.9 0.2 3.4 3 0 0 3 3 3 1 NACHT domain RsgA_GTPase PF03193.16 RLN59370.1 - 8.6e-05 22.5 0.2 0.032 14.1 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase IstB_IS21 PF01695.17 RLN59370.1 - 0.00028 20.7 0.1 2.8 7.6 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_25 PF13481.6 RLN59370.1 - 0.00048 19.7 0.5 0.087 12.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 RLN59370.1 - 0.00066 19.8 2.4 0.028 14.5 0.2 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_23 PF13476.6 RLN59370.1 - 0.00082 19.9 0.1 0.32 11.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 RLN59370.1 - 0.0031 16.9 1.1 0.97 8.7 0.1 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family RNA_helicase PF00910.22 RLN59370.1 - 0.0041 17.5 0.0 0.64 10.4 0.0 2.7 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.22 RLN59370.1 - 0.0053 16.0 1.1 0.4 9.8 0.1 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.6 RLN59370.1 - 0.0067 16.2 1.0 0.13 12.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 RLN59370.1 - 0.0071 16.6 0.0 0.4 10.9 0.0 3.5 4 0 0 4 4 4 1 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 RLN59370.1 - 0.015 14.6 0.1 3.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Viral_helicase1 PF01443.18 RLN59370.1 - 0.016 15.0 0.1 0.11 12.2 0.1 2.3 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 RLN59370.1 - 0.023 15.2 0.0 7.2 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 RLN59370.1 - 0.063 12.5 1.1 0.4 9.9 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 RLN59370.1 - 0.067 12.3 1.0 10 5.1 0.0 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_24 PF13479.6 RLN59370.1 - 0.16 11.7 0.1 7.5 6.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 RLN59370.1 - 0.2 11.2 0.9 2.8 7.5 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 RLN59370.1 - 0.24 10.9 0.5 18 4.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_21 PF13304.6 RLN59370.1 - 0.33 10.7 4.2 3.9 7.2 0.0 3.4 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AIG1 PF04548.16 RLN59370.1 - 2.6 7.3 4.1 23 4.2 0.2 3.1 3 0 0 3 3 3 0 AIG1 family Rax2 PF12768.7 RLN59370.1 - 5.9 6.3 9.0 0.87 9.0 0.3 2.4 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Sds3 PF08598.11 RLN59371.1 - 2e-07 31.2 5.6 2e-07 31.2 5.6 2.4 2 1 0 2 2 2 1 Sds3-like eIF-3_zeta PF05091.12 RLN59371.1 - 1.9 7.4 12.1 2.8 6.8 12.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PX PF00787.24 RLN59372.1 - 1.8e-10 40.8 0.1 4.2e-10 39.6 0.1 1.6 1 0 0 1 1 1 1 PX domain Cwf_Cwc_15 PF04889.12 RLN59372.1 - 0.074 12.8 0.9 0.12 12.1 0.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Methyltransf_PK PF05891.12 RLN59373.1 - 4.2e-71 238.9 0.0 5.1e-71 238.7 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 RLN59373.1 - 4.4e-08 33.7 0.0 3.6e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN59373.1 - 5.1e-07 30.3 0.0 1.1e-06 29.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 RLN59373.1 - 1.1e-06 28.1 0.0 2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 RLN59373.1 - 0.00012 22.8 0.0 0.00035 21.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN59373.1 - 0.00053 19.8 0.0 0.0017 18.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Rsm22 PF09243.10 RLN59373.1 - 0.0021 17.4 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 PLAC8 PF04749.17 RLN59397.1 - 3.5e-18 66.4 13.6 7.6e-18 65.4 13.6 1.5 1 1 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 RLN59398.1 - 7.3e-38 129.6 46.0 4.7e-19 69.2 18.6 2.1 2 0 0 2 2 2 2 PLAC8 family DUF4328 PF14219.6 RLN59398.1 - 0.12 11.9 2.2 6.7 6.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) fn3 PF00041.21 RLN59399.1 - 4.8e-37 126.2 15.5 0.00026 21.3 0.2 11.6 11 2 0 11 11 11 8 Fibronectin type III domain DUF2369 PF10179.9 RLN59399.1 - 0.0011 19.3 0.0 17 5.9 0.0 4.4 5 0 0 5 5 5 1 Uncharacterised conserved protein (DUF2369) Pur_ac_phosph_N PF16656.5 RLN59399.1 - 0.095 13.3 15.3 16 6.2 0.0 7.9 8 0 0 8 8 8 0 Purple acid Phosphatase, N-terminal domain MIP PF00230.20 RLN59412.1 - 2.5e-56 190.9 8.7 3.2e-56 190.6 8.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein PAP1 PF08601.10 RLN59413.1 - 0.83 9.3 12.0 0.54 9.9 8.5 2.0 2 0 0 2 2 2 0 Transcription factor PAP1 Pkinase PF00069.25 RLN59414.1 - 7.7e-58 195.9 0.0 1.3e-35 123.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN59414.1 - 8.2e-58 195.7 0.0 2e-36 125.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RLN59414.1 - 4.7e-05 22.9 0.0 0.039 13.3 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 RLN59414.1 - 0.0047 16.3 0.1 0.83 9.0 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RLN59414.1 - 0.024 14.2 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 RLN59414.1 - 0.22 11.4 12.1 0.16 11.9 1.0 4.2 4 2 1 5 5 5 0 Phosphotransferase enzyme family CTP_transf_1 PF01148.20 RLN59415.1 - 4.9e-05 23.2 17.8 0.00016 21.6 17.8 1.9 1 1 0 1 1 1 1 Cytidylyltransferase family MULE PF10551.9 RLN59428.1 - 3.2e-07 30.7 0.2 6.8e-07 29.6 0.2 1.5 1 0 0 1 1 1 1 MULE transposase domain CN_hydrolase PF00795.22 RLN59446.1 - 2.3e-29 102.6 0.0 3.3e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ribosomal_S15 PF00312.22 RLN59447.1 - 1.8e-32 111.4 1.4 2.1e-32 111.2 0.6 1.5 2 0 0 2 2 2 1 Ribosomal protein S15 UPRTase PF14681.6 RLN59448.1 - 4.6e-15 55.6 0.0 1.8e-11 43.9 0.0 2.3 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase CENP-B_N PF04218.13 RLN59448.1 - 8.4e-07 28.5 0.2 1.7e-06 27.6 0.2 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 RLN59448.1 - 0.0065 16.6 0.1 0.021 15.0 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 RLN59448.1 - 0.012 15.4 0.2 0.035 13.9 0.2 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Cpn60_TCP1 PF00118.24 RLN59449.1 - 5.4e-15 55.0 0.4 4.1e-10 38.9 0.1 2.5 3 0 0 3 3 3 2 TCP-1/cpn60 chaperonin family Nab6_mRNP_bdg PF10567.9 RLN59449.1 - 0.095 12.2 0.2 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 RNA-recognition motif LRR_9 PF14580.6 RLN59450.1 - 9e-14 51.3 0.0 1.6e-13 50.5 0.0 1.3 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 RLN59450.1 - 1.5e-08 34.7 0.1 0.00012 22.4 0.0 3.5 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN59450.1 - 1.8e-08 34.0 6.1 2.4e-07 30.4 0.9 3.4 3 2 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 RLN59450.1 - 0.0083 16.5 0.8 1.6 9.6 0.0 3.7 4 0 0 4 4 4 1 Leucine Rich Repeat GDI PF00996.18 RLN59451.1 - 2.4e-53 181.2 0.0 3.1e-19 68.8 0.0 3.1 2 1 1 3 3 3 3 GDP dissociation inhibitor Vfa1 PF08432.10 RLN59451.1 - 0.41 11.0 5.2 0.07 13.5 1.1 1.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 MDM10 PF12519.8 RLN59451.1 - 8.6 5.1 7.6 13 4.5 7.6 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Arm PF00514.23 RLN59452.1 - 2.5e-77 252.8 22.8 2.4e-07 30.6 0.1 14.2 14 0 0 14 14 14 14 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN59452.1 - 1.5e-12 47.8 31.1 0.12 12.9 0.4 10.3 5 2 6 11 11 11 7 HEAT-like repeat Atx10homo_assoc PF09759.9 RLN59452.1 - 1.3e-11 44.4 11.9 0.55 10.3 0.1 7.8 5 3 3 9 9 9 5 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 RLN59452.1 - 1.1e-08 34.6 6.0 1.8 9.0 0.1 10.6 12 0 0 12 12 12 1 HEAT repeat HEAT_2 PF13646.6 RLN59452.1 - 1.7e-08 34.8 37.3 0.029 14.7 0.9 7.3 2 2 5 7 7 7 4 HEAT repeats Hydantoinase_B PF02538.14 RLN59452.1 - 6.2e-06 24.9 0.0 0.099 11.0 0.0 4.1 3 1 0 3 3 3 2 Hydantoinase B/oxoprolinase DUF4800 PF16057.5 RLN59452.1 - 2.9e-05 23.5 0.0 2.3 7.4 0.0 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4800) DUF1186 PF06685.11 RLN59452.1 - 8.4e-05 22.1 0.0 0.013 14.9 0.0 3.1 1 1 2 3 3 3 1 Protein of unknown function (DUF1186) HEAT_PBS PF03130.16 RLN59452.1 - 0.009 16.6 48.1 11 7.0 0.4 13.3 14 0 0 14 14 14 1 PBS lyase HEAT-like repeat Pico_P2B PF01552.17 RLN59452.1 - 0.012 15.8 0.1 1.3e+02 2.8 0.0 5.1 6 0 0 6 6 6 0 Picornavirus 2B protein Op_neuropeptide PF08035.11 RLN59452.1 - 0.015 15.1 0.0 4.6 7.2 0.0 4.9 7 0 0 7 7 7 0 Opioids neuropeptide Alkyl_sulf_dimr PF14863.6 RLN59452.1 - 1.1 9.7 6.5 2.1 8.8 0.1 4.1 3 3 2 5 5 5 0 Alkyl sulfatase dimerisation Cwf_Cwc_15 PF04889.12 RLN59453.1 - 0.0074 16.1 2.0 0.011 15.5 2.0 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 RLN59453.1 - 0.037 14.4 6.4 0.074 13.4 6.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ras PF00071.22 RLN59454.1 - 5.2e-06 26.1 0.0 0.019 14.6 0.0 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 RLN59454.1 - 2.2e-05 24.7 0.0 0.00017 21.8 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN59454.1 - 0.0024 17.4 0.0 0.51 9.8 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 RLN59454.1 - 0.051 13.0 0.0 0.097 12.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 RLN59454.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MAPEG PF01124.18 RLN59455.1 - 7.4e-16 58.2 0.1 9.6e-16 57.9 0.1 1.2 1 0 0 1 1 1 1 MAPEG family MAPEG PF01124.18 RLN59456.1 - 2.3e-16 59.9 0.0 3.3e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 MAPEG family Tim17 PF02466.19 RLN59457.1 - 1.1e-10 41.8 4.9 1.6e-10 41.3 4.9 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TFR_dimer PF04253.15 RLN59458.1 - 1.3e-30 106.0 0.0 1.8e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain WD40 PF00400.32 RLN59459.1 - 2.4e-05 25.0 0.1 2.4 9.2 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.11 RLN59459.1 - 0.00094 19.1 0.0 0.0023 17.8 0.0 1.6 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A CDC45 PF02724.14 RLN59459.1 - 0.011 14.1 6.5 0.015 13.6 6.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 RLN59459.1 - 1.4 8.5 19.0 2.4 7.8 19.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 RLN59459.1 - 3.4 7.9 21.3 5.5 7.2 21.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 adh_short_C2 PF13561.6 RLN59460.1 - 4.6e-44 150.7 1.8 7.3e-44 150.1 1.8 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RLN59460.1 - 7.8e-31 107.1 0.7 1.3e-30 106.3 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Pex14_N PF04695.13 RLN59460.1 - 3.9e-15 56.8 2.4 3.9e-15 56.8 2.4 2.0 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region KR PF08659.10 RLN59460.1 - 0.00073 19.5 0.2 0.0013 18.6 0.2 1.5 1 1 0 1 1 1 1 KR domain Alg14 PF08660.11 RLN59461.1 - 4e-38 131.1 0.1 3.1e-23 82.6 0.0 2.2 2 0 0 2 2 2 2 Oligosaccharide biosynthesis protein Alg14 like MAPEG PF01124.18 RLN59462.1 - 6.6e-32 110.1 0.2 1.9e-12 47.2 0.1 4.2 3 1 1 4 4 4 4 MAPEG family Sec8_exocyst PF04048.14 RLN59462.1 - 0.00034 20.5 0.3 12 5.7 0.0 4.0 4 0 0 4 4 4 2 Sec8 exocyst complex component specific domain HupE_UreJ PF04955.12 RLN59462.1 - 0.0029 17.1 3.6 0.52 9.7 0.0 2.3 2 0 0 2 2 2 2 HupE / UreJ protein ELYS-bb PF16687.5 RLN59462.1 - 0.037 12.6 0.1 0.061 11.9 0.1 1.2 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin FYVE_2 PF02318.16 RLN59487.1 - 0.00041 20.6 8.4 0.00041 20.6 8.4 1.7 2 0 0 2 2 2 1 FYVE-type zinc finger ART PF01129.18 RLN59487.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase FYVE PF01363.21 RLN59487.1 - 0.027 14.6 16.5 0.065 13.4 16.5 1.6 1 0 0 1 1 1 0 FYVE zinc finger FYVE PF01363.21 RLN59488.1 - 0.0012 18.9 10.3 0.0026 17.9 10.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN59488.1 - 0.0021 18.3 4.7 0.0047 17.1 4.7 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger Ead_Ea22 PF13935.6 RLN59488.1 - 0.03 15.0 0.3 0.055 14.1 0.3 1.5 1 0 0 1 1 1 0 Ead/Ea22-like protein DUF1677 PF07911.13 RLN59488.1 - 0.2 12.1 6.3 0.52 10.7 6.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) MIP PF00230.20 RLN59505.1 - 3.7e-42 144.6 3.2 4.2e-42 144.4 3.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein Phage_holin_5_2 PF16079.5 RLN59505.1 - 0.53 10.7 0.1 0.53 10.7 0.1 2.8 4 1 0 4 4 4 0 Phage holin family Hol44, in holin superfamily V Asp PF00026.23 RLN59506.1 - 8.3e-76 255.4 0.3 9.7e-76 255.2 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RLN59506.1 - 3.5e-08 33.9 1.2 3.8e-06 27.2 0.1 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 RLN59506.1 - 0.07 12.9 0.0 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal FLgD_tudor PF13861.6 RLN59506.1 - 0.14 12.4 0.1 0.4 11.0 0.0 1.8 2 0 0 2 2 2 0 FlgD Tudor-like domain PhyH PF05721.13 RLN59508.1 - 1.9e-10 41.3 0.1 2.6e-10 40.9 0.1 1.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Anoctamin PF04547.12 RLN59509.1 - 1.2e-110 370.5 0.0 5.3e-104 348.6 0.0 2.1 2 0 0 2 2 2 2 Calcium-activated chloride channel Anoct_dimer PF16178.5 RLN59509.1 - 4.6e-08 33.1 4.2 1.4e-07 31.4 0.2 2.4 2 0 0 2 2 2 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin HTH_Tnp_Tc5 PF03221.16 RLN59509.1 - 1.3e-05 25.2 0.0 6e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain FTR1 PF03239.14 RLN59509.1 - 0.073 12.2 1.9 0.12 11.5 1.9 1.2 1 0 0 1 1 1 0 Iron permease FTR1 family RSN1_7TM PF02714.15 RLN59509.1 - 0.13 11.5 1.2 0.25 10.6 1.2 1.3 1 0 0 1 1 1 0 Calcium-dependent channel, 7TM region, putative phosphate Myb_DNA-binding PF00249.31 RLN59511.1 - 1.6e-10 41.0 0.0 2.6e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 RLN59512.1 - 4.5e-07 30.0 0.0 7.7e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3141 PF11339.8 RLN59512.1 - 0.11 10.9 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) DUF4173 PF13777.6 RLN59513.1 - 0.00045 19.7 4.2 0.00045 19.7 4.2 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4173) Myb_DNA-binding PF00249.31 RLN59514.1 - 2.6e-10 40.3 0.0 4.3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN59514.1 - 0.013 15.8 0.1 0.019 15.2 0.1 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain NIP_1 PF08995.10 RLN59515.1 - 0.086 13.2 0.4 0.086 13.2 0.4 2.4 2 0 0 2 2 2 0 Necrosis inducing protein-1 CspB_prodomain PF18425.1 RLN59515.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Csp protease B prodomain SR-25 PF10500.9 RLN59515.1 - 1.2 8.8 5.7 1.7 8.2 5.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 RLN59517.1 - 0.0084 15.5 0.0 0.02 14.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN59517.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 RLN59537.1 - 1e-47 162.8 0.0 4.9e-45 153.9 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN59537.1 - 6.9e-31 107.5 0.0 4.3e-30 104.9 0.0 2.2 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN59537.1 - 7.3e-05 21.7 0.2 0.00026 19.9 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Fez1 PF06818.15 RLN59537.1 - 0.00036 21.1 1.1 0.00062 20.3 1.1 1.4 1 0 0 1 1 1 1 Fez1 Rabaptin PF03528.15 RLN59537.1 - 0.0026 16.6 6.8 0.0038 16.0 6.8 1.1 1 0 0 1 1 1 1 Rabaptin DUF3552 PF12072.8 RLN59537.1 - 0.077 12.4 5.8 0.13 11.7 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) APH PF01636.23 RLN59537.1 - 0.48 10.3 3.8 2.3 8.1 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family LMSTEN PF07988.12 RLN59537.1 - 1.6 8.3 5.3 4.6 6.8 5.3 1.7 1 0 0 1 1 1 0 LMSTEN motif MFS_1 PF07690.16 RLN59538.1 - 1.2e-13 50.8 15.7 8.6e-09 34.8 3.7 2.5 3 0 0 3 3 3 2 Major Facilitator Superfamily Jacalin PF01419.17 RLN59538.1 - 7.6e-05 22.7 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 Jacalin-like lectin domain YrhC PF14143.6 RLN59538.1 - 0.028 14.5 0.1 3.9 7.6 0.0 2.9 2 0 0 2 2 2 0 YrhC-like protein zf-A20 PF01754.16 RLN59538.1 - 0.25 11.3 0.1 0.25 11.3 0.1 2.1 2 0 0 2 2 2 0 A20-like zinc finger RAI1 PF08652.11 RLN59563.1 - 1.1e-19 70.4 0.1 2.5e-19 69.2 0.1 1.7 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease EGF_2 PF07974.13 RLN59563.1 - 5.4e-07 29.9 48.8 0.0014 19.0 12.5 4.9 4 0 0 4 4 4 3 EGF-like domain EGF PF00008.27 RLN59563.1 - 0.00036 20.8 1.8 0.00036 20.8 1.8 4.8 4 0 0 4 4 4 1 EGF-like domain hEGF PF12661.7 RLN59563.1 - 0.0025 18.4 3.3 0.0025 18.4 3.3 6.3 5 1 0 5 5 5 2 Human growth factor-like EGF Laminin_EGF PF00053.24 RLN59563.1 - 0.18 11.9 47.0 0.052 13.7 14.1 4.2 2 1 2 4 4 4 0 Laminin EGF domain DUF2142 PF09913.9 RLN59563.1 - 0.2 10.5 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) DDE_1 PF03184.19 RLN59564.1 - 0.0036 17.0 0.0 0.004 16.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.25 RLN59565.1 - 2e-37 129.0 0.0 1.6e-36 126.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN59565.1 - 2e-35 122.4 0.0 3.9e-23 82.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase DEP PF00610.21 RLN59565.1 - 9.4e-06 25.6 0.0 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) APH PF01636.23 RLN59565.1 - 0.0062 16.5 0.1 0.015 15.2 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Syntaxin PF00804.25 RLN59565.1 - 0.24 11.1 0.3 0.41 10.3 0.3 1.3 1 0 0 1 1 1 0 Syntaxin MutL_C PF08676.11 RLN59566.1 - 3.9e-08 33.2 0.0 6.4e-07 29.2 0.0 2.5 2 1 0 2 2 2 1 MutL C terminal dimerisation domain LRR_6 PF13516.6 RLN59568.1 - 0.096 12.8 0.4 4.4 7.6 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeat Syja_N PF02383.18 RLN59569.1 - 2.5e-74 250.5 0.0 5.1e-74 249.5 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain Pkinase PF00069.25 RLN59570.1 - 2e-36 125.7 0.0 1.8e-35 122.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN59570.1 - 6.2e-31 107.6 0.0 4.5e-21 75.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DEP PF00610.21 RLN59570.1 - 5.1e-07 29.6 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) APH PF01636.23 RLN59570.1 - 0.0004 20.4 0.2 0.0013 18.7 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family SAM_2 PF07647.17 RLN59571.1 - 5.1e-06 26.5 3.2 2.7e-05 24.2 0.2 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RLN59571.1 - 1.7e-05 25.2 0.0 3.9e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CENP-B_dimeris PF09026.10 RLN59571.1 - 0.65 10.4 29.6 2.6 8.5 10.0 3.2 3 0 0 3 3 3 0 Centromere protein B dimerisation domain NOA36 PF06524.12 RLN59571.1 - 1.1 8.5 20.6 0.17 11.2 5.4 2.6 2 0 0 2 2 2 0 NOA36 protein Baculo_PEP_C PF04513.12 RLN59571.1 - 3.4 7.7 25.4 1.4 8.9 6.8 3.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus PGAP1 PF07819.13 RLN59572.1 - 1.2e-51 175.7 0.0 1.9e-51 175.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 RLN59572.1 - 0.00079 20.1 2.5 0.00079 20.1 2.5 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family MSP1a PF11670.8 RLN59572.1 - 0.04 13.2 0.0 0.13 11.5 0.0 1.8 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) ANAPC1 PF12859.7 RLN59572.1 - 0.12 12.9 0.8 8 7.0 0.4 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 V_ATPase_I PF01496.19 RLN59572.1 - 0.4 8.5 1.4 0.6 8.0 1.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4698 PF15769.5 RLN59572.1 - 0.65 9.0 7.0 0.93 8.5 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) DUF4834 PF16118.5 RLN59572.1 - 1.2 10.2 3.2 2.5 9.1 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) NPR3 PF03666.13 RLN59572.1 - 5.6 5.6 8.1 9.7 4.9 8.1 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CS PF04969.16 RLN59573.1 - 0.023 15.7 0.0 0.042 14.9 0.0 1.5 1 0 0 1 1 1 0 CS domain DUF4205 PF13898.6 RLN59574.1 - 6.8e-90 301.5 0.2 3.9e-85 285.8 0.0 3.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4205) WD40 PF00400.32 RLN59574.1 - 2.3e-20 72.5 11.8 7.4e-06 26.6 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN59574.1 - 9.9e-10 38.6 5.1 0.036 14.4 0.0 5.2 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Myb_DNA-binding PF00249.31 RLN59574.1 - 4.8e-06 26.7 1.4 1.8e-05 24.8 1.4 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN59574.1 - 3.1e-05 24.1 1.1 9.1e-05 22.6 1.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ge1_WD40 PF16529.5 RLN59574.1 - 0.0028 16.7 0.5 0.61 9.0 0.0 3.0 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein MADF_DNA_bdg PF10545.9 RLN59574.1 - 0.44 10.9 2.9 1.2 9.5 2.9 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Pkinase PF00069.25 RLN59575.1 - 1.7e-37 129.3 0.0 2.1e-25 89.6 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN59575.1 - 3.4e-37 128.1 0.0 3.7e-23 82.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 RLN59575.1 - 0.0011 18.9 0.8 0.0053 16.7 0.7 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family DEP PF00610.21 RLN59575.1 - 0.0027 17.7 0.1 0.0061 16.6 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ABC1 PF03109.16 RLN59575.1 - 0.046 13.9 0.1 0.093 12.9 0.1 1.4 1 0 0 1 1 1 0 ABC1 family Seadorna_VP7 PF07387.11 RLN59575.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SUI1 PF01253.22 RLN59576.1 - 1.1e-11 45.1 0.2 2e-11 44.3 0.2 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 RLN59576.1 - 2.3e-06 28.2 0.0 0.023 15.4 0.0 2.6 2 0 0 2 2 2 2 Pre-PUA-like domain PUA PF01472.20 RLN59576.1 - 0.0035 17.3 0.0 0.0091 15.9 0.0 1.8 1 0 0 1 1 1 1 PUA domain SWIB PF02201.18 RLN59576.1 - 0.13 12.2 0.0 0.34 10.8 0.0 1.8 1 1 0 1 1 1 0 SWIB/MDM2 domain NuA4 PF09340.10 RLN59577.1 - 3.1e-13 49.4 0.2 1.7e-12 47.0 0.0 2.3 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 SRP-alpha_N PF04086.13 RLN59577.1 - 1.4 8.8 13.7 2.2 8.1 13.7 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Na_H_Exchanger PF00999.21 RLN59578.1 - 1.1e-49 169.2 29.8 1.3e-49 169.1 29.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CTP_transf_3 PF02348.19 RLN59579.1 - 8.3e-49 166.5 0.0 1.1e-48 166.1 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 RLN59579.1 - 4e-06 27.3 0.0 6.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 RLN59579.1 - 0.0056 16.4 0.0 0.0088 15.8 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase FLYWCH_N PF15423.6 RLN59579.1 - 0.006 16.7 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 FLYWCH-type zinc finger-containing protein Metallophos PF00149.28 RLN59580.1 - 1.4e-11 45.3 0.1 2.6e-09 37.9 0.0 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Suc_Fer-like PF06999.12 RLN59580.1 - 0.055 13.3 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Sucrase/ferredoxin-like CLZ PF16526.5 RLN59582.1 - 0.12 12.8 0.8 18 5.8 0.1 3.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MTCP1 PF08991.10 RLN59600.1 - 0.0085 16.3 6.2 0.011 15.9 6.2 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 RLN59600.1 - 0.011 15.8 7.4 0.019 15.1 7.4 1.3 1 0 0 1 1 1 0 CHCH domain CX9C PF16860.5 RLN59600.1 - 0.051 13.6 5.6 0.069 13.2 5.6 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 RLN59600.1 - 0.11 12.3 5.7 0.14 11.9 5.7 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Apolipoprotein PF01442.18 RLN59601.1 - 0.0011 18.9 13.5 0.012 15.5 13.3 2.2 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain AAA_13 PF13166.6 RLN59601.1 - 0.0041 15.8 12.5 0.0056 15.4 12.5 1.1 1 0 0 1 1 1 1 AAA domain DUF883 PF05957.13 RLN59601.1 - 0.015 15.9 18.8 0.62 10.7 0.3 4.1 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) DUF842 PF05811.13 RLN59601.1 - 0.027 14.2 5.7 0.15 11.8 0.6 3.1 1 1 2 3 3 3 0 Eukaryotic protein of unknown function (DUF842) V-SNARE PF05008.15 RLN59601.1 - 0.028 14.8 1.2 0.028 14.8 1.2 2.8 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF3584 PF12128.8 RLN59601.1 - 0.034 11.7 10.9 0.045 11.3 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Methyltrn_RNA_4 PF09936.9 RLN59601.1 - 0.073 12.9 7.1 0.033 14.0 2.0 2.1 1 1 1 2 2 2 0 SAM-dependent RNA methyltransferase UPF0184 PF03670.13 RLN59601.1 - 0.13 12.7 2.4 0.24 11.8 0.6 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) ApoO PF09769.9 RLN59601.1 - 0.17 11.8 9.4 12 5.9 0.5 3.7 1 1 1 2 2 2 0 Apolipoprotein O Fib_alpha PF08702.10 RLN59601.1 - 0.2 11.9 6.5 0.32 11.2 1.4 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 RLN59601.1 - 0.26 10.1 9.0 0.19 10.6 2.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Prominin PF05478.11 RLN59601.1 - 2.1 6.2 6.9 1.5 6.6 3.9 1.6 1 1 0 1 1 1 0 Prominin Spectrin PF00435.21 RLN59601.1 - 2.1 8.9 7.8 1.3 9.5 0.1 2.9 2 1 1 3 3 3 0 Spectrin repeat Baculo_PEP_C PF04513.12 RLN59601.1 - 2.1 8.4 15.2 2.1 8.4 3.6 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fez1 PF06818.15 RLN59601.1 - 2.2 8.7 8.3 9.3 6.6 8.5 1.8 1 1 0 1 1 1 0 Fez1 Baculo_p24 PF05073.12 RLN59601.1 - 5.9 6.6 8.7 20 4.9 0.5 2.6 1 1 1 2 2 2 0 Baculovirus P24 capsid protein CREPT PF16566.5 RLN59601.1 - 6.6 6.9 7.5 2.5 8.3 0.6 2.7 1 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour DUF1690 PF07956.11 RLN59601.1 - 6.7 7.1 12.2 3.7 8.0 4.9 2.7 1 1 0 2 2 2 0 Protein of Unknown function (DUF1690) Muted PF14942.6 RLN59601.1 - 8.4 6.7 8.1 31 4.9 0.1 2.9 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein Apolipoprotein PF01442.18 RLN59602.1 - 0.049 13.5 52.3 38 4.1 30.3 4.0 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain CK2S PF15011.6 RLN59602.1 - 0.51 10.2 7.2 3 7.7 0.7 2.8 2 1 0 2 2 2 0 Casein Kinase 2 substrate DUF883 PF05957.13 RLN59602.1 - 3.3 8.4 50.1 1.3 9.7 11.2 7.1 2 2 3 7 7 7 0 Bacterial protein of unknown function (DUF883) VHS PF00790.19 RLN59603.1 - 2.4e-23 82.6 0.0 5.1e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 VHS domain MAGI_u1 PF16663.5 RLN59603.1 - 0.0084 16.2 0.8 0.031 14.3 0.0 2.3 2 1 0 2 2 2 1 Unstructured region on MAGI GAT PF03127.14 RLN59603.1 - 0.014 15.7 0.2 8.2 6.8 0.1 2.6 2 0 0 2 2 2 0 GAT domain malic PF00390.19 RLN59603.1 - 0.055 13.3 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Malic enzyme, N-terminal domain Dak1 PF02733.17 RLN59603.1 - 0.1 11.4 0.0 6.9 5.5 0.0 2.4 2 0 0 2 2 2 0 Dak1 domain HECT PF00632.25 RLN59604.1 - 8.7e-75 252.0 0.0 1.5e-74 251.3 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF3464 PF11947.8 RLN59604.1 - 2 8.2 6.8 0.1 12.4 1.1 1.7 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 RRM_1 PF00076.22 RLN59605.1 - 4.9e-17 61.5 0.0 2.2e-16 59.4 0.0 2.1 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 RLN59605.1 - 7.4e-05 22.7 1.1 0.00015 21.7 1.1 1.5 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.6 RLN59605.1 - 0.00039 20.0 0.0 0.00063 19.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.6 RLN59605.1 - 0.00096 19.1 0.2 0.0017 18.2 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 RLN59605.1 - 0.021 14.6 0.2 0.052 13.4 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Nrap_D2 PF17403.2 RLN59605.1 - 0.041 13.6 0.0 0.094 12.5 0.0 1.6 2 0 0 2 2 2 0 Nrap protein PAP/OAS-like domain zf-CCHC_4 PF14392.6 RLN59605.1 - 0.1 12.3 0.6 0.18 11.5 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle MPP6 PF10175.9 RLN59606.1 - 1.7e-11 44.8 0.4 2.9e-11 44.0 0.4 1.7 1 1 0 1 1 1 1 M-phase phosphoprotein 6 EF-hand_7 PF13499.6 RLN59607.1 - 2.4e-16 60.0 2.3 8.7e-16 58.1 1.2 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN59607.1 - 0.00032 20.4 0.3 0.015 15.2 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_13 PF17958.1 RLN59607.1 - 0.0046 16.7 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 RLN59607.1 - 0.0077 15.7 2.7 0.53 10.0 0.0 3.6 3 0 0 3 3 3 1 EF hand DUF3391 PF11871.8 RLN59607.1 - 0.037 14.6 2.5 4.6 7.8 2.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) SPARC_Ca_bdg PF10591.9 RLN59607.1 - 0.087 13.1 0.5 5.2 7.4 0.0 2.6 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 RLN59607.1 - 0.1 12.2 0.2 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 EF hand Copine PF07002.16 RLN59621.1 - 4e-41 140.8 0.0 6.3e-28 97.7 0.0 2.1 2 0 0 2 2 2 2 Copine vWA-TerF-like PF10138.9 RLN59621.1 - 9.3e-05 22.6 0.0 0.57 10.2 0.0 2.2 2 0 0 2 2 2 2 vWA found in TerF C terminus HEAT PF02985.22 RLN59622.1 - 1.6e-06 27.9 6.3 0.15 12.4 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 RLN59622.1 - 8.7e-06 26.0 4.0 0.0012 19.2 0.4 4.7 3 1 2 5 5 5 2 HEAT repeats Cnd1 PF12717.7 RLN59622.1 - 0.00016 21.8 0.9 0.013 15.6 0.2 3.4 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 RLN59622.1 - 0.0015 18.7 0.1 0.033 14.4 0.0 2.8 2 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Cohesin_HEAT PF12765.7 RLN59622.1 - 0.029 14.7 2.2 7.6 6.9 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 RLN59622.1 - 0.068 13.7 1.3 0.47 11.0 0.0 3.3 4 0 0 4 4 4 0 HEAT-like repeat Glyco_hydro_31 PF01055.26 RLN59653.1 - 2e-151 505.2 0.4 2.7e-151 504.7 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 RLN59653.1 - 4.3e-29 101.1 0.0 4e-28 97.9 0.0 2.3 2 0 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase CBM_25 PF03423.13 RLN59653.1 - 2.1e-28 98.7 9.9 1.6e-14 54.0 1.3 2.6 2 0 0 2 2 2 2 Carbohydrate binding domain (family 25) CBM53 PF16760.5 RLN59653.1 - 2.1e-17 63.5 5.4 1.5e-08 35.1 0.8 2.6 2 0 0 2 2 2 2 Starch/carbohydrate-binding module (family 53) CBM26 PF16738.5 RLN59653.1 - 3.4e-08 33.6 5.3 0.00049 20.3 0.5 3.0 2 0 0 2 2 2 2 Starch-binding module 26 Gal_mutarotas_2 PF13802.6 RLN59653.1 - 4.5e-08 33.3 0.1 1.6e-07 31.5 0.1 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like CBM_21 PF03370.13 RLN59653.1 - 0.12 12.5 2.6 3 8.1 0.3 2.6 2 0 0 2 2 2 0 Carbohydrate/starch-binding module (family 21) CBM_25 PF03423.13 RLN59654.1 - 1.7e-25 89.3 22.5 1.3e-12 47.9 5.0 2.7 2 1 1 3 3 3 2 Carbohydrate binding domain (family 25) CBM53 PF16760.5 RLN59654.1 - 3.4e-20 72.4 7.9 5.2e-12 46.2 1.2 2.4 2 0 0 2 2 2 2 Starch/carbohydrate-binding module (family 53) CBM26 PF16738.5 RLN59654.1 - 7.5e-07 29.3 9.3 0.002 18.3 1.5 3.0 2 0 0 2 2 2 2 Starch-binding module 26 NtCtMGAM_N PF16863.5 RLN59654.1 - 1e-06 28.9 0.0 2.6e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Big_4 PF07532.11 RLN59654.1 - 0.0046 16.7 2.2 0.048 13.4 1.0 2.7 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 4) CBM_20 PF00686.19 RLN59654.1 - 0.01 15.7 0.1 0.044 13.7 0.1 2.1 1 0 0 1 1 1 0 Starch binding domain Pyr_redox_2 PF07992.14 RLN59674.1 - 1.2e-38 133.1 0.1 1.5e-38 132.7 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RLN59674.1 - 1e-11 45.2 0.9 2.7e-08 34.2 0.3 2.6 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RLN59674.1 - 8.7e-11 41.6 0.1 2e-06 27.3 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RLN59674.1 - 2.3e-06 26.9 0.0 0.0084 15.2 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein K_oxygenase PF13434.6 RLN59674.1 - 5e-06 25.9 0.1 6.4e-05 22.3 0.1 2.0 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 RLN59674.1 - 5.5e-06 26.2 3.2 0.0092 15.6 0.0 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RLN59674.1 - 1.1e-05 25.6 0.1 0.051 13.8 0.0 2.9 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 RLN59674.1 - 2.6e-05 24.2 1.4 0.0027 17.7 0.0 3.3 3 1 1 4 4 4 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 RLN59674.1 - 2.6e-05 23.3 2.4 0.0054 15.6 0.0 3.1 3 0 0 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.14 RLN59674.1 - 0.00011 21.1 0.4 0.13 11.0 0.0 2.6 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 RLN59674.1 - 0.00089 18.6 0.4 0.3 10.3 0.0 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 RLN59674.1 - 0.0026 17.1 0.4 0.025 13.8 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.18 RLN59674.1 - 0.0033 17.7 0.5 1.1 9.6 0.3 2.4 2 0 0 2 2 2 1 TrkA-N domain FAD_binding_2 PF00890.24 RLN59674.1 - 0.04 13.0 1.0 1.5 7.8 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 RLN59674.1 - 0.06 13.8 0.1 14 6.1 0.1 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 RLN59675.1 - 1.4e-38 132.9 0.9 1.6e-38 132.6 0.9 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RLN59675.1 - 3.2e-13 50.0 0.7 9.2e-09 35.7 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RLN59675.1 - 1.3e-09 37.7 0.1 0.00054 19.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RLN59675.1 - 6.6e-09 35.8 1.5 0.0029 17.2 0.1 2.9 2 1 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 RLN59675.1 - 3.4e-08 33.0 0.2 0.00077 18.6 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 RLN59675.1 - 1e-07 32.0 0.3 0.0013 18.9 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 RLN59675.1 - 6.2e-07 28.6 1.2 0.00011 21.2 0.0 3.0 3 0 0 3 3 3 1 Tryptophan halogenase K_oxygenase PF13434.6 RLN59675.1 - 1.3e-06 27.8 0.4 3.1e-05 23.3 0.1 2.1 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 RLN59675.1 - 1.1e-05 25.4 1.2 0.0045 17.0 0.0 3.6 4 1 1 5 5 4 1 FAD-NAD(P)-binding HI0933_like PF03486.14 RLN59675.1 - 1.3e-05 24.1 2.4 0.0041 15.9 0.1 2.8 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.17 RLN59675.1 - 5.1e-05 22.6 0.5 0.04 13.1 0.0 2.3 2 0 0 2 2 2 2 Thi4 family AlaDh_PNT_C PF01262.21 RLN59675.1 - 0.0013 18.0 0.3 0.88 8.8 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 RLN59675.1 - 0.0015 17.7 0.3 0.3 10.1 0.1 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 RLN59675.1 - 0.0016 17.7 2.3 0.017 14.3 0.0 3.0 3 0 0 3 3 3 1 FAD binding domain TrkA_N PF02254.18 RLN59675.1 - 0.0022 18.2 0.6 0.88 9.8 0.0 3.2 4 0 0 4 4 4 1 TrkA-N domain GMC_oxred_N PF00732.19 RLN59675.1 - 0.028 13.8 0.0 3.9 6.7 0.0 2.3 2 0 0 2 2 2 0 GMC oxidoreductase ThiF PF00899.21 RLN59675.1 - 0.044 13.1 0.4 0.42 9.9 0.1 2.3 2 0 0 2 2 2 0 ThiF family NAD_binding_7 PF13241.6 RLN59675.1 - 0.076 13.5 0.1 6.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Malic_M PF03949.15 RLN59675.1 - 0.078 12.2 1.2 2 7.6 0.1 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain FAD_binding_2 PF00890.24 RLN59675.1 - 0.18 10.8 3.7 0.41 9.7 0.2 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 RLN59675.1 - 0.19 11.0 2.0 0.44 9.8 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RLN59676.1 - 1.1e-34 120.1 0.5 1.3e-34 119.8 0.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RLN59676.1 - 5.8e-14 52.4 0.7 3.3e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RLN59676.1 - 6.9e-09 35.7 1.9 0.0027 17.4 0.1 3.5 2 2 1 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 RLN59676.1 - 2e-08 33.7 0.8 1e-05 24.9 0.1 2.1 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 RLN59676.1 - 1.5e-07 31.6 0.6 0.064 13.5 0.1 3.3 2 1 0 3 3 3 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 RLN59676.1 - 4.2e-07 29.5 0.3 0.00046 19.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RLN59676.1 - 5.1e-07 29.1 0.0 0.00095 18.3 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein TrkA_N PF02254.18 RLN59676.1 - 0.00025 21.3 0.4 0.36 11.1 0.0 2.9 3 0 0 3 3 3 2 TrkA-N domain HI0933_like PF03486.14 RLN59676.1 - 0.00032 19.5 2.2 0.26 9.9 0.1 2.9 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.17 RLN59676.1 - 0.00035 19.9 0.6 0.53 9.5 0.1 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.6 RLN59676.1 - 0.0006 19.8 2.9 0.56 10.2 0.0 3.6 3 1 1 4 4 4 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 RLN59676.1 - 0.0017 17.3 4.9 0.031 13.1 0.1 3.2 3 1 1 4 4 4 1 Tryptophan halogenase GMC_oxred_N PF00732.19 RLN59676.1 - 0.0095 15.3 0.1 1.3 8.3 0.0 2.5 2 1 1 3 3 3 1 GMC oxidoreductase AlaDh_PNT_C PF01262.21 RLN59676.1 - 0.024 14.0 0.5 4 6.7 0.5 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 RLN59676.1 - 0.028 14.9 0.1 6 7.4 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Tubulin PF00091.25 RLN59676.1 - 0.046 13.9 0.5 0.21 11.7 0.5 1.9 1 1 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Malic_M PF03949.15 RLN59676.1 - 0.082 12.2 0.7 4 6.6 0.1 2.5 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain ApbA PF02558.16 RLN59676.1 - 0.12 12.0 0.1 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 RLN59676.1 - 0.24 10.7 0.1 0.24 10.7 0.1 1.9 2 0 0 2 2 2 0 ThiF family FAD_binding_3 PF01494.19 RLN59676.1 - 0.85 8.8 4.1 8.9 5.4 0.1 3.0 3 1 0 3 3 3 0 FAD binding domain GIDA PF01134.22 RLN59676.1 - 1 8.4 11.5 1.9 7.5 2.0 3.0 1 1 2 3 3 3 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 RLN59676.1 - 1.2 8.1 7.1 1.5 7.8 1.6 2.5 2 1 0 2 2 2 0 FAD binding domain PX PF00787.24 RLN59677.1 - 1.3e-09 38.1 0.4 2.2e-09 37.3 0.4 1.4 1 0 0 1 1 1 1 PX domain THF_DHG_CYH_C PF02882.19 RLN59678.1 - 1.1e-61 206.8 0.5 1.6e-61 206.3 0.5 1.1 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 RLN59678.1 - 2.1e-32 111.8 0.0 3.7e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF43 PF01861.16 RLN59678.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain BNIP2 PF12496.8 RLN59679.1 - 0.68 10.4 2.5 1.1 9.7 2.5 1.3 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Fumarate_red_C PF02300.17 RLN59680.1 - 0.17 12.0 1.1 20 5.3 0.0 2.7 3 0 0 3 3 3 0 Fumarate reductase subunit C SOG2 PF10428.9 RLN59680.1 - 6.8 5.8 23.0 10 5.2 23.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DIT1_PvcA PF05141.12 RLN59704.1 - 2.5e-78 263.4 0.0 3.2e-77 259.7 0.0 2.0 1 1 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein LAP1C PF05609.12 RLN59704.1 - 0.03 13.4 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DIT1_PvcA PF05141.12 RLN59705.1 - 3.2e-81 272.8 0.0 2.9e-80 269.7 0.0 1.9 1 1 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein MFS_1 PF07690.16 RLN59720.1 - 2.9e-34 118.5 19.3 3.9e-34 118.1 19.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 RLN59720.1 - 0.017 15.1 0.7 0.017 15.1 0.7 3.7 3 1 1 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III MRP-S31 PF15433.6 RLN59721.1 - 0.055 13.1 1.6 0.067 12.9 1.6 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 NPR3 PF03666.13 RLN59721.1 - 0.12 11.1 1.2 0.14 10.9 1.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NARP1 PF12569.8 RLN59721.1 - 0.86 8.4 6.5 1.4 7.8 6.5 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Bap31 PF05529.12 RLN59722.1 - 0.032 14.1 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region ABC_tran PF00005.27 RLN59739.1 - 9.5e-12 45.6 0.0 1.2e-11 45.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 RLN59739.1 - 3.5e-05 24.3 0.0 4.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 RLN59739.1 - 5.2e-05 22.9 0.8 0.00025 20.7 0.3 2.1 1 1 1 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN59739.1 - 0.00018 21.2 0.1 0.0003 20.4 0.1 1.4 1 1 1 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 RLN59739.1 - 0.00043 20.2 0.0 0.00052 19.9 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 RLN59739.1 - 0.0019 18.7 0.1 0.0033 18.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RLN59739.1 - 0.0023 18.5 0.0 0.0046 17.5 0.0 1.5 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 RLN59739.1 - 0.0045 17.3 0.0 0.0066 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 RLN59739.1 - 0.0064 16.4 0.0 0.0098 15.8 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_21 PF13304.6 RLN59739.1 - 0.013 15.4 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 RLN59739.1 - 0.02 15.1 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RLN59739.1 - 0.026 14.8 0.0 0.035 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 RLN59739.1 - 0.032 14.7 0.0 0.045 14.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 RLN59739.1 - 0.033 14.1 0.2 0.08 12.9 0.0 1.8 2 0 0 2 2 2 0 NTPase DUF87 PF01935.17 RLN59739.1 - 0.039 14.0 0.1 0.059 13.4 0.1 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain RNA_helicase PF00910.22 RLN59739.1 - 0.049 14.0 0.0 0.089 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 RLN59739.1 - 0.065 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.17 RLN59739.1 - 0.075 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase SMC_N PF02463.19 RLN59739.1 - 0.077 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 RLN59739.1 - 0.081 12.6 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 RLN59739.1 - 0.086 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 RLN59739.1 - 0.099 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 RLN59739.1 - 0.12 12.1 0.3 0.19 11.4 0.3 1.3 1 0 0 1 1 1 0 Cytidylate kinase ATP_bind_1 PF03029.17 RLN59739.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein cobW PF02492.19 RLN59739.1 - 0.14 11.7 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Cu-oxidase_2 PF07731.14 RLN59760.1 - 6.3e-36 123.1 8.7 1.8e-29 102.2 1.9 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN59760.1 - 1.3e-32 112.3 4.0 9.7e-32 109.5 0.1 2.9 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 RLN59760.1 - 2.3e-25 89.6 0.1 7.9e-25 87.8 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase UPRTase PF14681.6 RLN59765.1 - 1.5e-07 31.0 0.0 2.3e-05 24.0 0.1 2.1 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase EF-hand_7 PF13499.6 RLN59766.1 - 1.4e-35 121.6 15.4 1.4e-11 44.7 0.8 5.0 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 RLN59766.1 - 6.7e-29 97.3 16.7 0.00053 19.3 0.5 6.8 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.6 RLN59766.1 - 9.9e-25 84.3 13.5 0.00033 20.3 0.1 7.7 7 0 0 7 7 7 6 EF-hand domain EF-hand_8 PF13833.6 RLN59766.1 - 4.4e-24 84.1 8.6 1.3e-08 34.5 0.1 4.9 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 RLN59766.1 - 4.6e-15 54.3 19.0 0.0011 18.3 0.3 6.5 6 0 0 6 6 6 5 EF hand SPARC_Ca_bdg PF10591.9 RLN59766.1 - 3.4e-07 30.6 11.8 0.0042 17.4 0.2 4.3 3 1 1 4 4 4 3 Secreted protein acidic and rich in cysteine Ca binding region MBOAT PF03062.19 RLN59766.1 - 6.4e-05 22.5 0.3 0.00016 21.1 0.3 1.7 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family EF-hand_4 PF12763.7 RLN59766.1 - 0.0023 17.8 6.9 0.78 9.7 0.0 4.6 2 2 1 4 4 4 1 Cytoskeletal-regulatory complex EF hand SHOCT PF09851.9 RLN59766.1 - 0.037 13.8 3.7 8.5 6.3 0.3 4.0 3 0 0 3 3 3 0 Short C-terminal domain Adenine_glyco PF03352.13 RLN59766.1 - 1.5 8.6 5.6 0.13 12.0 0.3 2.0 2 0 0 2 2 2 0 Methyladenine glycosylase MFS_1 PF07690.16 RLN59767.1 - 9.6e-21 74.1 35.6 9.6e-21 74.1 35.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN59767.1 - 1.1e-10 40.9 9.4 1.1e-10 40.9 9.4 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter OTU PF02338.19 RLN59768.1 - 0.0013 19.2 0.0 0.0018 18.8 0.0 1.2 1 0 0 1 1 1 1 OTU-like cysteine protease MFS_1 PF07690.16 RLN59769.1 - 1.7e-23 83.1 47.0 8.7e-22 77.5 27.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN59769.1 - 1.3e-11 44.0 4.6 1.3e-11 44.0 4.6 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN59770.1 - 3.4e-19 69.0 34.8 3.4e-19 69.0 34.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN59770.1 - 1e-09 37.8 9.7 1e-09 37.8 9.7 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter PAPS_reduct PF01507.19 RLN59771.1 - 0.044 13.8 0.8 0.044 13.8 0.8 2.2 2 1 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family DUF1515 PF07439.11 RLN59771.1 - 7.9 6.6 10.5 0.44 10.6 1.0 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1515) Baculo_PEP_C PF04513.12 RLN59771.1 - 9.5 6.3 18.0 17 5.4 0.1 3.6 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 RLN59772.1 - 0.0018 18.5 3.1 0.0032 17.7 3.1 1.3 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family KxDL PF10241.9 RLN59772.1 - 0.079 13.2 3.7 0.47 10.8 0.9 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein TMF_TATA_bd PF12325.8 RLN59772.1 - 0.093 13.0 8.3 0.3 11.3 1.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FliJ PF02050.16 RLN59772.1 - 0.093 13.0 11.2 0.17 12.1 0.1 2.9 3 0 0 3 3 3 0 Flagellar FliJ protein SlyX PF04102.12 RLN59772.1 - 0.22 12.2 9.6 2.2 8.9 0.6 2.5 2 0 0 2 2 2 0 SlyX Tropomyosin_1 PF12718.7 RLN59772.1 - 0.24 11.5 10.6 0.13 12.4 2.2 2.4 1 1 1 2 2 2 0 Tropomyosin like DUF641 PF04859.12 RLN59772.1 - 0.33 11.3 0.2 0.33 11.3 0.2 2.6 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) Kre28 PF17097.5 RLN59772.1 - 0.4 9.6 3.9 2.9 6.8 0.1 2.1 2 0 0 2 2 2 0 Spindle pole body component CENP-H PF05837.12 RLN59772.1 - 0.63 10.5 7.1 0.44 11.0 5.5 1.5 2 0 0 2 2 1 0 Centromere protein H (CENP-H) TMF_DNA_bd PF12329.8 RLN59772.1 - 0.67 10.0 7.5 5.3 7.1 1.6 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 RLN59772.1 - 0.8 9.0 11.0 3.3 7.0 11.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 RLN59772.1 - 1.1 9.0 8.7 4 7.3 3.1 2.3 2 0 0 2 2 2 0 Septum formation initiator MscS_porin PF12795.7 RLN59772.1 - 1.1 8.7 15.5 16 4.9 15.6 2.1 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Fungal_TACC PF12709.7 RLN59772.1 - 1.6 9.2 8.8 2.8 8.4 1.5 2.4 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Cnn_1N PF07989.11 RLN59772.1 - 2 8.6 7.3 0.81 9.9 1.9 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Csm1_N PF18504.1 RLN59772.1 - 3 8.3 10.2 5 7.5 0.7 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain HrpB7 PF09486.10 RLN59772.1 - 3.4 8.0 10.3 2.4 8.5 0.4 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) ZapB PF06005.12 RLN59772.1 - 4.1 7.9 15.5 5.4 7.5 7.0 2.4 2 0 0 2 2 2 0 Cell division protein ZapB OmpH PF03938.14 RLN59772.1 - 4.5 7.6 8.9 8.3 6.8 8.9 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3552 PF12072.8 RLN59772.1 - 4.8 6.5 11.0 5.6 6.3 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) ADIP PF11559.8 RLN59772.1 - 7.2 6.7 11.8 9.7 6.3 1.2 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding HIP1_clath_bdg PF16515.5 RLN59772.1 - 8.9 7.0 13.5 0.65 10.6 1.3 2.6 3 0 0 3 3 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 RLN59772.1 - 9.6 5.0 10.5 76 2.0 10.5 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein adh_short PF00106.25 RLN59774.1 - 1.5e-22 80.0 0.0 2.2e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN59774.1 - 3.6e-17 62.7 0.0 4.1e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase IQ PF00612.27 RLN59775.1 - 0.0006 19.4 0.4 0.0019 17.9 0.4 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Ion_trans PF00520.31 RLN59776.1 - 4.1e-44 150.7 28.0 1.1e-24 87.0 5.8 2.2 2 0 0 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 RLN59776.1 - 6.5e-25 86.9 11.0 7.5e-13 48.3 2.0 2.9 2 0 0 2 2 2 2 Ion channel cNMP_binding PF00027.29 RLN59776.1 - 1.5e-11 44.2 0.2 0.00019 21.4 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain IRK PF01007.20 RLN59776.1 - 0.17 11.7 2.8 9.1 6.1 0.2 2.5 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain fn3 PF00041.21 RLN59821.1 - 8.3e-48 160.7 35.5 8.1e-14 51.7 0.1 12.1 12 1 0 12 12 12 10 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RLN59821.1 - 2e-13 50.7 12.3 4.5e-05 23.9 0.1 8.3 8 0 0 8 8 8 3 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 RLN59821.1 - 7.9e-09 35.8 5.2 0.058 13.8 0.0 6.5 8 0 0 8 8 8 2 Uncharacterised conserved protein (DUF2369) NAR2 PF16974.5 RLN59821.1 - 0.0033 16.9 1.0 11 5.4 0.0 4.4 4 0 0 4 4 4 1 High-affinity nitrate transporter accessory Cofilin_ADF PF00241.20 RLN59822.1 - 1.6e-05 24.7 0.0 2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SRP19 PF01922.17 RLN59823.1 - 6.8e-30 103.9 0.0 1.2e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein Cofilin_ADF PF00241.20 RLN59824.1 - 1e-09 38.2 0.0 1.4e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cofilin_ADF PF00241.20 RLN59825.1 - 0.00073 19.3 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein UCH PF00443.29 RLN59826.1 - 2.9e-25 89.3 0.0 6.5e-21 75.0 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 RLN59826.1 - 4.3e-13 48.8 0.0 8.7e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UCH_1 PF13423.6 RLN59826.1 - 1.3e-12 48.0 3.3 5.7e-11 42.6 1.9 2.9 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 RLN59826.1 - 2.1e-05 25.0 0.0 1.7 9.3 0.0 3.7 3 0 0 3 3 3 2 DUSP domain zf-RanBP PF00641.18 RLN59826.1 - 6.2e-05 22.2 1.6 6.2e-05 22.2 1.6 2.9 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others MAP65_ASE1 PF03999.12 RLN59826.1 - 0.0022 16.8 7.9 0.023 13.4 1.9 3.2 2 1 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) AroM PF07302.11 RLN59826.1 - 0.016 14.6 0.1 0.042 13.2 0.1 1.7 1 0 0 1 1 1 0 AroM protein Rad60-SLD PF11976.8 RLN59826.1 - 0.024 14.5 0.0 0.068 13.0 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ABC_tran_CTD PF16326.5 RLN59826.1 - 0.05 13.9 3.2 82 3.6 0.2 4.9 4 0 0 4 4 4 0 ABC transporter C-terminal domain zf-FPG_IleRS PF06827.14 RLN59826.1 - 0.11 12.4 5.4 0.19 11.7 0.0 3.3 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS DHO_dh PF01180.21 RLN59827.1 - 1.6e-103 346.0 0.0 1.9e-103 345.8 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 RLN59827.1 - 0.027 13.9 0.2 0.057 12.8 0.2 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase PWWP PF00855.17 RLN59828.1 - 2e-11 44.1 0.0 2e-11 44.1 0.0 4.4 4 0 0 4 4 4 1 PWWP domain Ribosomal_S2 PF00318.20 RLN59829.1 - 8.5e-28 97.1 0.0 3.9e-15 55.7 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 RLN59829.1 - 0.00055 21.2 18.7 0.00094 20.5 18.7 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Uma2 PF05685.12 RLN59839.1 - 0.0022 17.6 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Putative restriction endonuclease Glyco_hydro_31 PF01055.26 RLN59864.1 - 1e-155 519.3 2.3 1.6e-155 518.7 2.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 RLN59864.1 - 1.7e-29 102.3 0.3 3.6e-29 101.3 0.3 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase CBM_25 PF03423.13 RLN59864.1 - 1e-11 45.0 0.5 3.8e-11 43.2 0.5 2.0 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) Gal_mutarotas_2 PF13802.6 RLN59864.1 - 3.8e-10 39.9 0.4 1.5e-09 38.0 0.4 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like CBM53 PF16760.5 RLN59864.1 - 6.4e-09 36.3 1.7 2e-08 34.7 1.7 1.9 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) zf-HIT PF04438.16 RLN59864.1 - 1 9.3 3.9 1.8 8.5 3.9 1.4 1 0 0 1 1 1 0 HIT zinc finger DNA_pol_A_exo1 PF01612.20 RLN59865.1 - 2.4e-15 56.7 0.1 7.9e-15 55.0 0.1 1.9 1 1 0 1 1 1 1 3'-5' exonuclease PPR_3 PF13812.6 RLN59865.1 - 0.0036 17.3 0.0 20 5.4 0.0 4.8 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR PF01535.20 RLN59865.1 - 0.13 12.5 0.5 23 5.5 0.0 3.9 4 0 0 4 4 4 0 PPR repeat PPR_1 PF12854.7 RLN59865.1 - 0.18 11.5 0.3 0.63 9.8 0.1 2.0 2 0 0 2 2 2 0 PPR repeat PPR_2 PF13041.6 RLN59865.1 - 0.2 11.9 1.8 13 6.1 0.0 3.3 3 0 0 3 3 3 0 PPR repeat family PPR_1 PF12854.7 RLN59866.1 - 2.8e-06 26.9 0.5 1.8e-05 24.3 0.0 2.4 3 0 0 3 3 3 1 PPR repeat PPR_2 PF13041.6 RLN59866.1 - 8.8e-05 22.6 0.0 0.0012 19.0 0.0 2.3 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.6 RLN59866.1 - 0.00043 20.3 0.0 0.0011 19.0 0.0 1.7 1 1 1 2 2 2 1 Pentatricopeptide repeat domain PPR PF01535.20 RLN59866.1 - 0.013 15.7 0.0 0.098 12.9 0.0 2.2 2 0 0 2 2 2 0 PPR repeat SET PF00856.28 RLN59890.1 - 3.1e-16 60.2 0.1 2e-15 57.6 0.1 1.9 1 1 0 1 1 1 1 SET domain DUF3860 PF12976.7 RLN59917.1 - 0.018 15.1 0.5 1.4 9.0 0.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) HTH_12 PF08461.10 RLN59917.1 - 0.14 12.2 0.5 0.52 10.3 0.4 2.0 1 1 1 2 2 2 0 Ribonuclease R winged-helix domain Mannosyl_trans3 PF11051.8 RLN59918.1 - 2.4e-36 125.5 0.0 2.1e-35 122.4 0.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative ChiW_Ig_like PF18683.1 RLN59919.1 - 0.007 16.6 0.8 0.0085 16.3 0.7 1.3 1 1 0 1 1 1 1 Chitinase W immunoglobulin-like domain FeS PF04060.13 RLN59919.1 - 0.43 10.3 2.3 1.5 8.5 1.6 2.4 2 1 0 2 2 2 0 Putative Fe-S cluster Ras PF00071.22 RLN59943.1 - 1.4e-37 128.8 0.3 1.6e-37 128.6 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN59943.1 - 1.3e-13 51.2 0.1 2.3e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN59943.1 - 1.8e-05 24.3 0.1 2e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PhyH PF05721.13 RLN59956.1 - 7.3e-13 49.3 1.0 7.9e-12 45.9 1.0 2.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ADK PF00406.22 RLN59957.1 - 1.7e-87 291.1 0.0 2e-42 144.9 0.0 2.3 2 0 0 2 2 2 2 Adenylate kinase DUF4821 PF16092.5 RLN59957.1 - 2.2e-66 224.2 0.0 3.1e-61 207.3 0.0 3.3 3 1 0 3 3 3 2 Domain of unknown function (DUF4821) AAA_17 PF13207.6 RLN59957.1 - 1.4e-46 158.3 0.0 1.4e-22 80.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 RLN59957.1 - 3.8e-13 50.1 0.0 1.3e-05 25.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 RLN59957.1 - 7.1e-11 42.5 0.0 0.00035 20.7 0.0 4.1 3 1 1 4 4 4 2 AAA domain ADK_lid PF05191.14 RLN59957.1 - 3.7e-07 30.0 0.0 0.045 13.7 0.0 2.9 2 0 0 2 2 2 2 Adenylate kinase, active site lid Pyr_redox_2 PF07992.14 RLN59957.1 - 5e-07 29.2 0.0 3.3e-06 26.5 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Hydin_ADK PF17213.3 RLN59957.1 - 7.6e-06 26.3 5.4 0.47 10.7 0.1 4.6 3 2 2 5 5 5 2 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 RLN59957.1 - 6.3e-05 22.8 0.0 0.37 10.5 0.0 2.7 2 0 0 2 2 2 2 Cytidylate kinase Pyr_redox PF00070.27 RLN59957.1 - 0.063 13.8 0.2 0.22 12.1 0.2 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Myotub-related PF06602.14 RLN59958.1 - 4.2e-118 394.3 0.0 7.2e-118 393.5 0.0 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.21 RLN59958.1 - 7.2e-16 58.1 14.4 1.5e-15 57.1 14.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger C2 PF00168.30 RLN59958.1 - 1.2e-15 57.7 0.0 3.1e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain Y_phosphatase3 PF13350.6 RLN59958.1 - 0.0049 16.9 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 RLN59958.1 - 0.0089 15.8 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Uds1 PF15456.6 RLN59958.1 - 0.43 10.7 3.2 0.38 10.9 0.1 2.5 2 0 0 2 2 2 0 Up-regulated During Septation FYVE_2 PF02318.16 RLN59958.1 - 1.6 8.9 11.0 4 7.7 11.0 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger LSM PF01423.22 RLN59959.1 - 1.3e-14 53.6 0.3 1.7e-14 53.2 0.3 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RLN59959.1 - 0.00076 19.6 0.0 0.00091 19.3 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain MIOX PF05153.15 RLN59960.1 - 1.5e-40 139.3 4.2 1.7e-40 139.2 4.2 1.0 1 0 0 1 1 1 1 Myo-inositol oxygenase Sdh5 PF03937.16 RLN59960.1 - 0.054 13.4 0.7 0.094 12.7 0.6 1.5 1 1 0 1 1 1 0 Flavinator of succinate dehydrogenase DUF5021 PF16424.5 RLN59962.1 - 0.017 15.0 6.0 4 7.2 0.1 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF5021) DUF4012 PF13196.6 RLN59962.1 - 5.5 7.4 5.7 10 6.6 0.0 4.0 3 2 3 6 6 6 0 Protein of unknown function (DUF4012) UDPG_MGDP_dh_N PF03721.14 RLN59963.1 - 4.9e-59 199.1 0.4 7.5e-59 198.5 0.4 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 RLN59963.1 - 6.1e-34 116.6 0.1 1.3e-31 109.1 0.1 2.6 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 RLN59963.1 - 7.9e-31 106.1 0.0 1.8e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 RLN59963.1 - 0.0019 18.4 0.0 0.026 14.7 0.0 2.7 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Acyltransferase PF01553.21 RLN59964.1 - 7e-15 54.8 0.0 1.3e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase EF-hand_1 PF00036.32 RLN59964.1 - 2.4e-14 51.7 1.2 0.00027 20.2 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 RLN59964.1 - 8.7e-14 50.2 5.5 0.00052 19.7 0.2 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 RLN59964.1 - 2.4e-12 45.8 5.2 0.00029 20.2 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 RLN59964.1 - 3e-10 40.4 5.4 4.6e-05 23.8 2.3 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RLN59964.1 - 1.6e-05 24.6 1.1 0.25 11.2 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 RLN59964.1 - 0.0013 18.6 5.5 0.075 13.0 0.3 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RLN59964.1 - 0.041 14.2 1.4 0.46 10.8 0.1 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region ZapB PF06005.12 RLN59965.1 - 0.033 14.6 4.9 0.033 14.6 4.9 4.8 1 1 4 5 5 5 0 Cell division protein ZapB Adhesin_P1_N PF18652.1 RLN59965.1 - 0.04 13.9 0.1 0.15 12.1 0.1 2.1 1 0 0 1 1 1 0 Adhesin P1 N-terminal domain DUF4988 PF16378.5 RLN59965.1 - 0.048 13.3 0.4 0.84 9.3 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function DUF4618 PF15397.6 RLN59965.1 - 0.065 12.6 20.8 0.019 14.4 5.3 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF4618) Baculo_PEP_C PF04513.12 RLN59965.1 - 0.11 12.6 13.4 1.2 9.2 2.6 3.8 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 RLN59965.1 - 0.15 12.6 11.3 3 8.4 1.9 3.9 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TetR_C_24 PF17932.1 RLN59965.1 - 0.31 11.3 4.8 0.22 11.8 0.2 2.8 1 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF4472 PF14739.6 RLN59965.1 - 1.9 9.3 21.6 1.1 10.1 2.4 4.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4472) Lectin_N PF03954.14 RLN59965.1 - 2 8.2 18.0 7.5 6.3 11.4 4.0 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain V_ATPase_I PF01496.19 RLN59965.1 - 5.1 4.9 14.7 12 3.6 14.7 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 RLN59965.1 - 9.3 5.7 26.3 1.5 8.4 9.6 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit TraK PF06586.11 RLN59966.1 - 0.0089 15.7 0.1 0.011 15.5 0.1 1.2 1 1 0 1 1 1 1 TraK protein Tetraspanin PF00335.20 RLN59967.1 - 6e-06 26.1 0.3 6.8e-06 26.0 0.3 1.0 1 0 0 1 1 1 1 Tetraspanin family Yip1 PF04893.17 RLN59967.1 - 0.075 12.8 4.4 0.089 12.5 4.4 1.1 1 0 0 1 1 1 0 Yip1 domain DUF2892 PF11127.8 RLN59967.1 - 0.082 13.0 0.2 0.082 13.0 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2892) DUF4689 PF15755.5 RLN59967.1 - 0.13 11.9 0.5 0.16 11.6 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4689) ADK PF00406.22 RLN59968.1 - 9.2e-78 259.5 0.0 3e-44 150.7 0.0 2.6 3 0 0 3 3 3 2 Adenylate kinase AAA_17 PF13207.6 RLN59968.1 - 1.4e-43 148.6 0.0 6.1e-23 81.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 RLN59968.1 - 1.1e-12 48.6 0.0 3.3e-06 27.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 RLN59968.1 - 8.8e-11 42.1 1.6 0.00093 19.4 0.4 4.4 3 1 0 3 3 3 2 AAA domain Hydin_ADK PF17213.3 RLN59968.1 - 3.3e-06 27.5 2.3 0.61 10.3 0.2 4.1 2 2 1 4 4 4 2 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 RLN59968.1 - 5e-05 23.1 0.0 0.012 15.4 0.0 2.8 3 0 0 3 3 3 1 Cytidylate kinase Zeta_toxin PF06414.12 RLN59968.1 - 0.0011 18.3 0.2 0.49 9.6 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.6 RLN59968.1 - 0.004 17.4 0.0 1.9 8.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 RLN59968.1 - 0.0066 15.9 0.0 0.89 9.0 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA PF00004.29 RLN59968.1 - 0.0078 16.6 0.0 2.7 8.4 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN59968.1 - 0.0086 16.4 0.0 7.1 6.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 RLN59968.1 - 0.014 15.1 0.6 17 5.0 0.0 4.0 5 0 0 5 5 5 0 Thymidylate kinase ADK_lid PF05191.14 RLN59968.1 - 0.026 14.5 0.0 0.064 13.2 0.0 1.7 1 0 0 1 1 1 0 Adenylate kinase, active site lid RuvB_N PF05496.12 RLN59968.1 - 0.033 13.9 0.3 2.9 7.6 0.0 2.7 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 RLN59968.1 - 0.038 14.4 0.1 4.9 7.5 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 RLN59968.1 - 0.058 13.1 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 RLN59968.1 - 0.081 12.8 0.1 3 7.7 0.0 2.5 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.21 RLN59968.1 - 0.13 11.6 0.1 1 8.7 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Thioredoxin PF00085.20 RLN59969.1 - 6.3e-08 32.6 0.0 2.1e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin FAD_binding_3 PF01494.19 RLN59985.1 - 6.5e-52 176.9 0.0 3.1e-51 174.7 0.0 2.1 2 1 0 2 2 2 1 FAD binding domain Nuc_sug_transp PF04142.15 RLN59986.1 - 3.7e-26 92.0 2.7 4.8e-26 91.7 2.7 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 RLN59986.1 - 2e-05 24.0 3.5 6.2e-05 22.4 3.9 1.7 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport Yip1 PF04893.17 RLN59986.1 - 7e-05 22.6 0.1 7e-05 22.6 0.1 2.6 2 1 1 3 3 3 1 Yip1 domain UAA PF08449.11 RLN59986.1 - 8.2e-05 21.9 0.4 0.00011 21.5 0.4 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 RLN59986.1 - 0.031 14.4 14.6 0.23 11.6 5.8 2.6 2 1 0 2 2 2 0 EamA-like transporter family WD40 PF00400.32 RLN59989.1 - 5.8e-19 68.1 18.3 2.7e-07 31.2 0.2 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 RLN59989.1 - 3e-17 62.6 0.1 4.8e-16 58.8 0.0 2.5 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 RLN59989.1 - 2.9e-08 33.9 0.4 0.022 15.0 0.1 3.3 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 RLN59989.1 - 0.075 11.0 0.4 0.33 8.9 0.1 2.0 1 1 1 2 2 2 0 IKI3 family Pox_Ag35 PF03286.14 RLN59989.1 - 0.4 10.4 9.3 0.39 10.5 0.8 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RXT2_N PF08595.11 RLN59989.1 - 6 6.9 9.7 2.9 7.9 1.1 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal FAM176 PF14851.6 RLN59989.1 - 7.1 6.3 9.0 0.86 9.3 0.3 2.3 2 0 0 2 2 2 0 FAM176 family SQS_PSY PF00494.19 RLN59990.1 - 9.3e-30 104.0 1.7 1.1e-29 103.8 1.7 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase SOAR PF16533.5 RLN59991.1 - 0.055 13.4 5.1 0.12 12.4 5.1 1.5 1 0 0 1 1 1 0 STIM1 Orai1-activating region Syntaxin-6_N PF09177.11 RLN59991.1 - 0.23 12.1 3.4 13 6.4 0.0 2.6 3 0 0 3 3 3 0 Syntaxin 6, N-terminal BCIP PF13862.6 RLN59992.1 - 1.2e-48 165.6 0.0 2.1e-48 164.9 0.0 1.4 1 0 0 1 1 1 1 p21-C-terminal region-binding protein SEO_C PF14577.6 RLN59992.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Sieve element occlusion C-terminus PRKCSH-like PF12999.7 RLN59994.1 - 3.2e-24 85.7 8.1 1.1e-23 83.9 8.1 1.9 1 1 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 RLN59994.1 - 1.3e-12 47.7 0.1 2.5e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 RLN59994.1 - 0.012 15.8 5.6 0.012 15.8 5.6 2.7 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A MutS_III PF05192.18 RLN59994.1 - 0.021 15.0 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 MutS domain III Tropomyosin_1 PF12718.7 RLN59994.1 - 0.04 14.1 0.7 0.094 12.9 0.7 1.5 1 0 0 1 1 1 0 Tropomyosin like Fib_alpha PF08702.10 RLN59994.1 - 0.09 13.0 2.0 0.19 11.9 2.0 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family OmpH PF03938.14 RLN59994.1 - 0.46 10.8 5.6 0.87 9.9 5.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) UPF0242 PF06785.11 RLN59994.1 - 0.94 9.5 3.9 1.6 8.8 3.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-C3HC4_2 PF13923.6 RLN59996.1 - 4.5e-09 36.0 17.0 7.8e-09 35.2 17.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN59996.1 - 2.2e-07 31.1 16.7 3.8e-07 30.3 16.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RLN59996.1 - 2.3e-07 30.6 15.7 3.7e-07 29.9 15.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN59996.1 - 2.2e-06 27.6 11.0 2.2e-06 27.6 11.0 2.2 1 1 1 2 2 2 1 RING-type zinc-finger PTCB-BRCT PF12738.7 RLN59996.1 - 1.8e-05 24.6 0.0 3.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain zf-C3HC4 PF00097.25 RLN59996.1 - 2e-05 24.4 18.6 3.5e-05 23.6 18.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN59996.1 - 3.9e-05 23.5 16.3 6.3e-05 22.8 16.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain BRCT PF00533.26 RLN59996.1 - 6.4e-05 23.3 0.0 0.00035 20.9 0.0 2.1 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain zf-RING_6 PF14835.6 RLN59996.1 - 0.0018 18.1 5.2 0.0035 17.2 5.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 RLN59996.1 - 0.0039 17.3 17.7 0.0088 16.2 17.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RLN59996.1 - 0.03 14.2 15.4 0.056 13.3 15.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RTT107_BRCT_5 PF16770.5 RLN59996.1 - 0.046 13.6 0.0 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain zf-rbx1 PF12678.7 RLN59996.1 - 0.054 13.8 14.1 0.21 11.9 14.1 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 RLN59996.1 - 0.21 11.8 12.5 0.44 10.7 12.5 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-P11 PF03854.14 RLN59996.1 - 4.7 7.0 11.3 8.5 6.1 11.3 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 RLN59996.1 - 7.9 6.4 15.1 0.19 11.5 8.1 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Vps8 PF12816.7 RLN59997.1 - 1.3e-58 197.8 0.0 7.5e-57 192.0 0.0 2.8 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 RLN59997.1 - 3.1e-12 46.6 2.0 0.00022 21.1 0.0 3.5 3 0 0 3 3 3 3 Region in Clathrin and VPS Chromo PF00385.24 RLN59997.1 - 6.2e-07 29.2 0.1 1.2e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain WD40 PF00400.32 RLN59997.1 - 0.0026 18.5 0.1 0.022 15.6 0.1 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN59997.1 - 0.018 15.3 0.0 0.056 13.7 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.8 RLN59997.1 - 0.091 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region Spt46 PF17734.1 RLN59997.1 - 0.11 12.3 3.2 0.14 11.9 0.0 2.6 2 0 0 2 2 2 0 Spermatogenesis-associated protein 46 UPF0565 PF10561.9 RLN59997.1 - 0.82 8.8 3.6 0.34 10.1 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 MORN PF02493.20 RLN59998.1 - 4.7e-63 205.5 94.6 1.9e-06 27.4 4.5 18.4 19 0 0 19 19 19 17 MORN repeat Zn_peptidase_2 PF04298.12 RLN60000.1 - 0.0098 15.3 0.5 0.021 14.2 0.3 1.6 1 1 0 1 1 1 1 Putative neutral zinc metallopeptidase DctQ PF04290.12 RLN60000.1 - 5.4 6.9 12.9 0.066 13.1 1.5 2.9 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Orexin PF02072.15 RLN60001.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Prepro-orexin CTP_transf_1 PF01148.20 RLN60002.1 - 5e-42 144.5 11.1 5.8e-42 144.3 11.1 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family CarS-like PF01864.17 RLN60002.1 - 0.00073 19.6 0.6 0.01 15.8 0.5 2.6 1 1 0 1 1 1 1 CDP-archaeol synthase LRR_6 PF13516.6 RLN60003.1 - 0.0016 18.3 8.7 0.17 12.0 0.1 5.5 7 0 0 7 7 7 1 Leucine Rich repeat LRR_4 PF12799.7 RLN60003.1 - 0.0033 17.8 7.2 0.075 13.5 0.9 4.5 2 1 3 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN60003.1 - 0.023 15.2 2.7 11 7.0 0.3 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat CHAD PF05235.14 RLN60003.1 - 0.042 13.8 0.4 0.073 13.0 0.4 1.3 1 0 0 1 1 1 0 CHAD domain GalKase_gal_bdg PF10509.9 RLN60004.1 - 4.4e-21 74.2 0.1 9.1e-21 73.2 0.1 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 RLN60004.1 - 2.3e-16 59.9 0.4 6.6e-16 58.4 0.1 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 RLN60004.1 - 2.3e-13 50.2 1.9 5.6e-13 48.9 0.8 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain Pkinase_Tyr PF07714.17 RLN60006.1 - 2.5e-45 154.8 0.0 4.6e-44 150.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN60006.1 - 1.6e-40 139.2 0.0 2.6e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 RLN60006.1 - 0.14 11.0 0.0 0.29 10.0 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Orn_Arg_deC_N PF02784.16 RLN60007.1 - 4.4e-41 140.9 0.0 6.5e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 RLN60007.1 - 6.4e-12 45.6 0.0 1.1e-11 44.8 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain EMP24_GP25L PF01105.24 RLN60008.1 - 0.034 14.1 0.4 0.082 12.8 0.1 1.9 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Rdx PF10262.9 RLN60010.1 - 1.1e-27 96.0 0.0 1.5e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Rdx family Pkinase PF00069.25 RLN60011.1 - 9.4e-11 41.6 0.2 1e-10 41.5 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN60011.1 - 1.1e-05 24.9 0.2 1.2e-05 24.8 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DPCD PF14913.6 RLN60011.1 - 0.066 12.6 0.2 0.077 12.4 0.2 1.1 1 0 0 1 1 1 0 DPCD protein family Rogdi_lz PF10259.9 RLN60012.1 - 5.7e-08 32.5 0.0 8.7e-07 28.7 0.0 2.2 1 1 1 2 2 2 2 Rogdi leucine zipper containing protein TPR_12 PF13424.6 RLN60013.1 - 0.0013 19.0 2.4 2.5 8.4 1.6 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat Ank_2 PF12796.7 RLN60045.1 - 5.2e-151 491.6 33.7 2.7e-16 59.9 0.2 11.0 1 1 10 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN60045.1 - 2.3e-124 404.3 18.1 7.9e-10 39.1 0.0 15.1 6 2 10 17 17 17 17 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN60045.1 - 1.4e-106 347.1 33.5 2.9e-07 30.6 0.1 21.6 1 1 21 22 22 22 22 Ankyrin repeats (many copies) Ank PF00023.30 RLN60045.1 - 1.4e-102 332.0 46.0 0.00017 21.8 0.0 23.0 23 0 0 23 23 23 21 Ankyrin repeat Ank_3 PF13606.6 RLN60045.1 - 2.9e-96 303.7 14.2 0.042 14.4 0.0 22.9 23 0 0 23 23 23 22 Ankyrin repeat DUF1949 PF09186.11 RLN60045.1 - 1.3e-16 60.2 8.5 5.9 6.9 0.0 11.7 11 0 0 11 11 11 6 Domain of unknown function (DUF1949) SIP PF04954.13 RLN60045.1 - 2.4e-16 60.3 2.0 1.5 9.4 0.0 8.6 1 1 7 8 8 8 6 Siderophore-interacting protein Atu4866 PF11512.8 RLN60045.1 - 3.2e-05 24.2 0.0 1.3e+02 3.0 0.0 7.1 8 0 0 8 8 8 0 Agrobacterium tumefaciens protein Atu4866 ArsP_1 PF03773.13 RLN60045.1 - 0.078 12.1 25.4 25 3.9 0.1 9.1 11 0 0 11 11 11 0 Predicted permease TFIIB PF00382.19 RLN60045.1 - 3.7 7.7 11.7 2.6e+02 1.8 0.0 6.3 6 0 0 6 6 6 0 Transcription factor TFIIB repeat Ank_2 PF12796.7 RLN60046.1 - 1.1e-43 147.6 5.9 6.1e-16 58.8 0.2 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN60046.1 - 8.9e-35 118.6 0.8 1.5e-08 35.0 0.0 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN60046.1 - 6.3e-29 99.7 5.2 1.4e-06 28.5 0.1 7.2 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 RLN60046.1 - 4.5e-27 93.3 8.0 0.00037 20.8 0.0 7.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 RLN60046.1 - 1.5e-24 83.4 0.5 0.055 14.0 0.0 8.0 7 0 0 7 7 7 6 Ankyrin repeat Pkinase_Tyr PF07714.17 RLN60046.1 - 3.1e-20 72.6 0.0 9.8e-09 34.9 0.0 3.5 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN60046.1 - 4e-19 69.0 0.0 7.9e-10 38.5 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain DUF1949 PF09186.11 RLN60046.1 - 0.00047 20.0 0.1 7.1 6.6 0.0 3.8 3 0 0 3 3 3 2 Domain of unknown function (DUF1949) Pkinase_Tyr PF07714.17 RLN60061.1 - 1.3e-30 106.5 0.0 1.5e-17 63.7 0.0 2.9 2 1 1 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 RLN60061.1 - 1.3e-21 77.2 0.0 1.3e-12 47.7 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain ABC1 PF03109.16 RLN60061.1 - 3.5e-05 24.0 0.0 0.00011 22.4 0.0 1.8 1 0 0 1 1 1 1 ABC1 family Ras PF00071.22 RLN60063.1 - 2.2e-08 33.9 0.0 2.9e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN60063.1 - 1.7e-07 31.5 0.0 2.1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 RLN60063.1 - 0.024 14.7 0.0 0.032 14.3 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase TAF4 PF05236.14 RLN60063.1 - 0.24 11.1 0.6 0.22 11.2 0.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family AA_kinase PF00696.28 RLN60064.1 - 1.5e-25 90.2 0.1 2.4e-25 89.6 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dh PF01118.24 RLN60064.1 - 9.6e-23 80.9 0.0 1.1e-21 77.5 0.0 2.7 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 RLN60064.1 - 0.00053 20.1 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus CPSase_L_D2 PF02786.17 RLN60065.1 - 1.2e-100 335.4 0.2 1.5e-83 279.4 0.1 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 RLN60065.1 - 5.1e-50 168.6 0.0 1.1e-49 167.5 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 RLN60065.1 - 9.7e-44 149.4 0.0 8.2e-42 143.1 0.0 2.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 RLN60065.1 - 1.3e-36 125.6 0.0 6.6e-36 123.3 0.0 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 RLN60065.1 - 3.2e-14 52.9 0.1 4e-08 33.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 RLN60065.1 - 7.5e-14 51.7 0.3 2e-06 27.5 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus GARS_A PF01071.19 RLN60065.1 - 7.1e-06 25.9 0.1 0.0039 17.0 0.0 2.8 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peptidase_C26 PF07722.13 RLN60065.1 - 0.00011 22.0 1.5 0.045 13.5 0.2 3.4 2 1 0 2 2 2 1 Peptidase C26 ATPgrasp_Ter PF15632.6 RLN60065.1 - 0.00015 21.6 0.1 0.0019 17.9 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 RLN60065.1 - 0.0034 17.4 0.0 0.6 10.2 0.0 2.8 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 RLN60065.1 - 0.0084 15.7 0.0 2 8.0 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 RLN60065.1 - 0.047 13.1 0.0 1.5 8.2 0.1 2.8 2 1 1 3 3 3 0 ATP-grasp domain Cauli_VI PF01693.16 RLN60086.1 - 6.4e-08 32.8 0.7 2.4e-07 30.9 1.6 1.5 2 0 0 2 2 2 1 Caulimovirus viroplasmin WW PF00397.26 RLN60087.1 - 2.2e-08 34.0 0.1 4.8e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 WW domain PDZ PF00595.24 RLN60087.1 - 6.4e-05 23.2 0.0 0.00018 21.8 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RLN60087.1 - 0.00025 21.3 0.0 0.00057 20.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Macoilin PF09726.9 RLN60087.1 - 0.09 11.3 4.3 0.13 10.8 4.3 1.2 1 0 0 1 1 1 0 Macoilin family Ank_5 PF13857.6 RLN60088.1 - 6.5e-28 96.4 12.6 2.1e-06 27.9 0.2 9.8 4 1 6 10 10 10 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN60088.1 - 2.5e-24 85.7 0.7 6.6e-07 29.8 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN60088.1 - 1.8e-23 82.5 8.0 1.1e-06 29.1 0.0 6.6 4 2 4 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN60088.1 - 8.4e-12 44.2 5.1 28 5.7 0.0 9.6 7 3 3 10 10 10 0 Ankyrin repeat Ank PF00023.30 RLN60088.1 - 0.0047 17.3 1.4 34 5.1 0.0 5.7 3 2 1 4 4 4 0 Ankyrin repeat CTC1_2 PF15491.6 RLN60088.1 - 0.027 13.8 0.0 1.1 8.5 0.0 2.5 1 1 0 2 2 2 0 CST, telomere maintenance, complex subunit CTC1 Chorion_S16 PF05836.12 RLN60088.1 - 2.4 8.4 5.1 23 5.3 0.2 3.7 2 2 2 4 4 4 0 Chorion protein S16 Herpes_pp85 PF04637.12 RLN60092.1 - 0.16 10.4 0.5 0.22 9.9 0.5 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) CENP-F_leu_zip PF10473.9 RLN60104.1 - 0.0096 16.0 11.6 0.36 10.8 0.2 2.6 2 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ank_3 PF13606.6 RLN60108.1 - 1.8e-07 30.9 0.1 0.22 12.2 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 RLN60108.1 - 4.3e-07 30.4 0.8 1.3e-05 25.7 0.8 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN60108.1 - 1.3e-06 28.8 0.5 0.0013 19.2 0.2 3.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN60108.1 - 1.9e-06 28.0 2.7 0.018 15.4 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN60108.1 - 3e-05 24.2 3.4 0.015 15.8 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeat C2 PF00168.30 RLN60108.1 - 0.00027 21.2 0.0 0.00052 20.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain tRNA-synt_1e PF01406.19 RLN60109.1 - 0.22 10.9 4.9 0.48 9.7 2.6 2.2 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF4795 PF16043.5 RLN60110.1 - 0.0014 18.2 0.6 0.0099 15.5 0.6 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) DUF4407 PF14362.6 RLN60110.1 - 0.12 11.7 2.8 4 6.7 2.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CwsA PF10814.8 RLN60110.1 - 0.27 11.4 1.2 1.1 9.4 0.0 2.4 3 0 0 3 3 3 0 Cell wall synthesis protein CwsA Ank_2 PF12796.7 RLN60111.1 - 3.4e-33 114.1 11.1 9.7e-14 51.7 1.7 3.6 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN60111.1 - 5.1e-26 90.7 0.6 7.5e-07 29.6 0.0 5.0 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN60111.1 - 1e-23 83.0 9.7 2e-09 37.5 0.1 5.0 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN60111.1 - 1.1e-23 80.7 0.4 0.00031 21.0 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 RLN60111.1 - 2.6e-18 65.6 11.5 1.3e-05 25.4 0.2 5.8 6 0 0 6 6 6 4 Ankyrin repeat Glyco_transf_28 PF03033.20 RLN60112.1 - 2.9e-07 30.6 0.0 3.1e-06 27.3 0.0 2.4 2 1 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain TauE PF01925.19 RLN60113.1 - 7.3e-21 74.9 25.6 2e-11 44.0 10.5 2.8 2 1 0 2 2 2 2 Sulfite exporter TauE/SafE SH PF01445.17 RLN60113.1 - 0.08 12.9 3.4 0.13 12.2 0.2 2.4 2 0 0 2 2 2 0 Viral small hydrophobic protein Rep_fac-A_C PF08646.10 RLN60132.1 - 7.1e-42 142.6 4.3 1.7e-41 141.4 4.3 1.7 1 0 0 1 1 1 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 RLN60132.1 - 1.2e-31 108.5 0.7 3e-30 104.0 1.2 2.4 2 0 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 RLN60132.1 - 3.5e-14 52.6 0.8 2.4e-08 33.8 0.0 3.8 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain Rep-A_N PF04057.12 RLN60132.1 - 0.00094 19.2 0.6 0.0063 16.5 0.1 2.5 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain Zn_Tnp_IS1595 PF12760.7 RLN60132.1 - 0.13 12.3 1.9 0.3 11.1 1.9 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DZR PF12773.7 RLN60132.1 - 0.54 10.3 4.8 1.2 9.3 4.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 RLN60132.1 - 0.95 9.5 11.0 0.31 11.1 7.8 1.8 2 0 0 2 2 2 0 zinc-ribbons PADR1 PF08063.12 RLN60132.1 - 2.1 8.2 8.4 6.1 6.7 8.4 1.7 1 0 0 1 1 1 0 PADR1 (NUC008) domain zf_UBZ PF18439.1 RLN60132.1 - 7.3 6.3 6.2 46 3.7 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger WW PF00397.26 RLN60133.1 - 4.5e-31 106.6 33.2 1.2e-07 31.7 6.6 4.3 4 0 0 4 4 4 4 WW domain IQ PF00612.27 RLN60133.1 - 1e-05 24.8 10.0 0.2 11.5 1.2 4.8 4 0 0 4 4 4 2 IQ calmodulin-binding motif ATPase-cat_bd PF12156.8 RLN60133.1 - 0.0064 17.2 1.7 1.4 9.7 0.0 3.2 3 0 0 3 3 3 1 Putative metal-binding domain of cation transport ATPase HNHc_6 PF16784.5 RLN60133.1 - 0.027 14.0 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative HNHc nuclease DUF4585 PF15232.6 RLN60133.1 - 0.033 14.2 2.6 1.7 8.8 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4585) Hydrolase_2 PF07486.12 RLN60133.1 - 0.42 11.5 12.0 0.5 11.3 0.1 3.7 3 1 1 4 4 4 0 Cell Wall Hydrolase Glyco_hyd_101C PF17451.2 RLN60133.1 - 1.3 9.3 6.6 22 5.3 0.0 3.3 3 0 0 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain DUF4404 PF14357.6 RLN60133.1 - 3.8 8.2 6.1 2.8 8.6 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Herpes_BLLF1 PF05109.13 RLN60134.1 - 1.8 6.5 6.3 2.8 5.8 6.3 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) SAM_adeno_trans PF01887.16 RLN60135.1 - 0.036 13.5 0.0 3.2 7.1 0.0 2.1 1 1 1 2 2 2 0 S-adenosyl-l-methionine hydroxide adenosyltransferase Big_1 PF02369.16 RLN60135.1 - 0.055 13.5 13.7 0.14 12.2 2.6 3.6 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) PIP5K PF01504.18 RLN60152.1 - 5.6e-66 222.6 0.0 7.4e-66 222.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Caa3_CtaG PF09678.10 RLN60152.1 - 0.011 15.2 0.8 0.023 14.2 0.8 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) Peptidase_C70 PF12385.8 RLN60155.1 - 0.07 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 adh_short PF00106.25 RLN60161.1 - 2.6e-41 141.2 0.1 3.6e-41 140.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN60161.1 - 9.2e-25 87.6 0.0 1.2e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN60161.1 - 3.3e-08 33.7 0.1 4.5e-08 33.2 0.1 1.1 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 RLN60161.1 - 0.0036 16.8 0.4 0.0086 15.5 0.1 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 RLN60161.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 RLN60161.1 - 0.027 13.9 1.1 0.22 10.9 1.1 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 RLN60161.1 - 0.16 11.1 0.1 0.19 10.8 0.1 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Zip PF02535.22 RLN60162.1 - 3.6e-08 33.0 14.7 7.4e-08 32.0 14.7 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter DUF350 PF03994.14 RLN60162.1 - 0.62 10.3 0.0 0.62 10.3 0.0 4.6 7 0 0 7 7 7 0 Domain of Unknown Function (DUF350) Zip PF02535.22 RLN60163.1 - 7.9e-12 45.0 16.5 5.8e-11 42.2 16.5 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter Methyltransf_24 PF13578.6 RLN60165.1 - 1.7e-10 41.9 0.1 3.8e-10 40.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.17 RLN60165.1 - 0.00058 19.1 0.0 0.001 18.3 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.6 RLN60165.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.4 2 0 0 2 2 2 0 Methyltransferase domain CPSF_A PF03178.15 RLN60166.1 - 2.4e-59 201.3 0.0 6.6e-59 199.8 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 RLN60166.1 - 2.9e-32 112.0 0.0 6.2e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Sugar_tr PF00083.24 RLN60167.1 - 2.8e-100 336.3 23.3 3.2e-100 336.1 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN60167.1 - 5.7e-28 97.9 32.9 1.2e-20 73.8 9.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RLN60167.1 - 0.043 12.4 16.4 0.023 13.3 2.9 2.9 3 1 0 3 3 3 0 MFS/sugar transport protein Gly-zipper_Omp PF13488.6 RLN60167.1 - 0.52 10.3 4.5 1.9 8.5 0.4 2.9 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.15 RLN60167.1 - 2.3 8.2 7.5 0.19 11.6 0.3 2.7 3 0 0 3 3 3 0 Glycine zipper 2TM domain Kinesin PF00225.23 RLN60205.1 - 4.7e-110 367.6 0.0 4.7e-110 367.6 0.0 3.5 2 1 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 RLN60205.1 - 6.1e-28 97.6 0.2 8.3e-27 94.0 0.0 2.7 2 0 0 2 2 2 1 Microtubule binding Rsbr_N PF08678.10 RLN60205.1 - 0.5 10.5 14.4 0.29 11.2 4.9 3.4 2 1 0 2 2 2 0 Rsbr N terminal MFS_1 PF07690.16 RLN60206.1 - 1.5e-48 165.5 25.8 1e-47 162.8 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 RLN60206.1 - 0.019 13.3 6.9 0.49 8.6 0.1 2.2 2 0 0 2 2 2 0 BT1 family Wzy_C PF04932.15 RLN60206.1 - 5 6.7 10.4 0.1 12.2 0.2 2.7 2 1 0 2 2 2 0 O-Antigen ligase PPR_2 PF13041.6 RLN60207.1 - 6.2e-55 183.2 0.0 4.9e-08 33.0 0.0 12.6 9 3 3 12 12 12 12 PPR repeat family PPR_3 PF13812.6 RLN60207.1 - 2.1e-31 107.8 0.0 1.1e-05 25.4 0.0 10.4 6 4 7 13 13 13 8 Pentatricopeptide repeat domain PPR PF01535.20 RLN60207.1 - 7.1e-27 91.7 8.5 5.9e-05 23.0 0.0 13.3 15 0 0 15 15 15 7 PPR repeat PPR_long PF17177.4 RLN60207.1 - 2.4e-23 82.6 3.0 1.8e-08 34.1 0.1 6.3 5 2 2 7 7 7 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 RLN60207.1 - 5.6e-20 70.7 1.2 0.0012 18.5 0.0 10.9 13 0 0 13 13 13 4 PPR repeat ATP13 PF12921.7 RLN60207.1 - 2.3e-05 24.2 0.0 0.81 9.6 0.0 4.1 4 1 1 5 5 5 2 Mitochondrial ATPase expression N_NLPC_P60 PF12912.7 RLN60207.1 - 0.072 13.5 0.0 0.25 11.7 0.0 1.9 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term RNA_pol_3_Rpc31 PF11705.8 RLN60207.1 - 5.1 7.3 14.0 4.3 7.5 5.7 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 SNF2_N PF00176.23 RLN60208.1 - 2.4e-50 171.2 0.0 6.2e-50 169.9 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN60208.1 - 5.9e-15 55.6 0.0 1.1e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN60208.1 - 7.3e-09 35.9 0.0 3.4e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RLN60208.1 - 2.9e-07 30.4 0.0 1.2e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AA_permease_2 PF13520.6 RLN60209.1 - 1.9e-49 168.7 38.6 1.9e-49 168.7 38.6 1.7 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 RLN60209.1 - 2e-32 112.4 42.1 2e-32 112.4 42.1 1.7 1 1 1 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 RLN60209.1 - 4e-16 58.8 5.4 4e-16 58.8 5.4 4.0 3 0 0 3 3 3 1 C-terminus of AA_permease Spore_permease PF03845.13 RLN60209.1 - 1.7e-05 23.8 14.2 1.7e-05 23.8 14.2 2.6 2 1 0 2 2 2 1 Spore germination protein TMEM72 PF16054.5 RLN60209.1 - 2.8 7.6 14.1 1.1 8.9 5.0 2.7 2 0 0 2 2 2 0 Transmembrane protein family 72 DEAD PF00270.29 RLN60210.1 - 2.9e-42 144.4 0.1 1.5e-41 142.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN60210.1 - 6e-29 100.6 0.0 1.6e-28 99.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN60210.1 - 7.8e-09 35.8 0.0 6e-07 29.6 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RLN60210.1 - 0.0045 17.3 0.7 0.78 10.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain BSP_II PF05432.11 RLN60210.1 - 0.27 10.9 34.0 0.027 14.2 28.9 1.8 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) RNase_H2_suC PF08615.11 RLN60210.1 - 0.79 9.9 7.6 1.2e+02 2.8 7.5 3.0 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Presenilin PF01080.17 RLN60210.1 - 2.4 6.8 15.6 0.028 13.2 7.4 1.7 2 0 0 2 2 2 0 Presenilin TPR_1 PF00515.28 RLN60211.1 - 0.012 15.4 0.6 14 5.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MCM_lid PF17855.1 RLN60211.1 - 0.091 13.2 2.3 0.62 10.5 0.2 2.5 2 0 0 2 2 2 0 MCM AAA-lid domain Trp_syntA PF00290.20 RLN60212.1 - 1.3e-85 286.4 0.2 1.6e-85 286.1 0.2 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain Glyco_hydro_17 PF00332.18 RLN60213.1 - 1.3e-15 57.8 0.4 5.5e-09 36.0 0.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Tfb4 PF03850.14 RLN60214.1 - 8.9e-79 264.8 0.0 1.2e-78 264.4 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb4 Vps36-NZF-N PF16988.5 RLN60214.1 - 0.64 9.4 3.6 6.7 6.2 3.6 2.2 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Peptidase_M24 PF00557.24 RLN60215.1 - 7.1e-42 143.5 0.1 9.2e-42 143.1 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 LRR_8 PF13855.6 RLN60216.1 - 0.00016 21.3 1.3 0.013 15.2 0.1 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RLN60216.1 - 0.072 13.5 2.4 0.69 10.4 1.9 2.6 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) ABC_tran PF00005.27 RLN60218.1 - 1.4e-59 200.5 0.0 2.1e-30 106.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 RLN60218.1 - 8e-43 146.9 34.3 2.7e-33 115.5 12.2 2.7 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 RLN60218.1 - 1.6e-21 77.4 1.9 1.6e-07 31.5 0.1 4.2 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RLN60218.1 - 3.7e-05 24.3 2.2 0.016 15.7 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 RLN60218.1 - 0.0004 20.7 0.0 0.48 10.7 0.0 3.6 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.19 RLN60218.1 - 0.0019 17.7 0.0 6.8 6.1 0.0 3.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RLN60218.1 - 0.0019 17.9 3.8 0.017 14.8 0.3 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain MukB PF04310.12 RLN60218.1 - 0.002 18.0 1.5 0.55 10.0 0.2 2.4 2 0 0 2 2 2 2 MukB N-terminal AAA_30 PF13604.6 RLN60218.1 - 0.0038 17.0 0.8 0.62 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 RLN60218.1 - 0.0051 16.7 0.4 0.94 9.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 RLN60218.1 - 0.074 12.7 0.0 0.94 9.1 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_16 PF13191.6 RLN60218.1 - 0.1 13.0 0.1 18 5.6 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain DUF4162 PF13732.6 RLN60218.1 - 0.12 13.1 1.7 5.4 7.8 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4162) Rad17 PF03215.15 RLN60218.1 - 0.14 12.1 0.0 0.88 9.5 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 RLN60218.1 - 0.23 11.1 5.1 6 6.4 0.5 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain 60KD_IMP PF02096.20 RLN60218.1 - 3.9 7.4 6.1 0.97 9.3 0.1 2.6 2 1 0 2 2 2 0 60Kd inner membrane protein Ank_5 PF13857.6 RLN60219.1 - 1.3e-17 63.6 2.1 3.8e-10 39.8 0.3 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN60219.1 - 1.3e-09 38.5 0.1 5.1e-09 36.6 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 RLN60219.1 - 9.1e-09 35.4 1.1 1.8e-05 25.0 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat IQ PF00612.27 RLN60219.1 - 9.8e-08 31.2 10.9 0.008 15.9 0.2 4.8 5 0 0 5 5 5 2 IQ calmodulin-binding motif Ank_4 PF13637.6 RLN60219.1 - 3.5e-07 30.6 0.2 0.0012 19.3 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN60219.1 - 7e-07 29.1 0.2 0.00066 19.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat RRP36 PF06102.12 RLN60219.1 - 0.1 12.6 6.1 0.21 11.5 6.1 1.5 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 MRP-L28 PF09812.9 RLN60220.1 - 0.019 15.1 0.0 0.019 15.1 0.0 2.5 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L28 NST1 PF13945.6 RLN60220.1 - 0.4 10.8 9.9 1.6 8.8 3.7 3.5 3 0 0 3 3 3 0 Salt tolerance down-regulator Transket_pyr PF02779.24 RLN60236.1 - 1.9e-15 57.0 0.0 2.1e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DENN PF02141.21 RLN60237.1 - 2.2e-29 102.7 0.0 7.2e-28 97.8 0.0 2.5 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 RLN60237.1 - 1.6e-08 35.1 0.2 7e-08 33.1 0.1 2.3 2 0 0 2 2 2 1 uDENN domain DUF2786 PF10979.8 RLN60237.1 - 2.9 7.9 6.1 26 4.8 0.9 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) Transketolase_C PF02780.20 RLN60238.1 - 8.4e-33 112.9 0.0 1.3e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 RLN60238.1 - 0.0041 17.4 0.0 0.056 13.8 0.0 2.0 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II SpoIIE PF07228.12 RLN60239.1 - 5.4e-08 33.0 0.3 7e-07 29.4 0.1 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 RLN60239.1 - 2.3e-07 30.7 0.4 2.3e-07 30.7 0.4 2.1 1 1 1 2 2 2 1 Protein phosphatase 2C FAD_binding_1 PF00667.20 RLN60240.1 - 3e-58 197.0 0.1 5.8e-58 196.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain POR_N PF01855.19 RLN60240.1 - 9.9e-14 51.6 1.2 1.7e-13 50.8 1.2 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg NAD_binding_1 PF00175.21 RLN60240.1 - 4.8e-12 46.5 0.0 3.5e-11 43.7 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain POR PF01558.18 RLN60240.1 - 2.7e-07 30.8 0.2 7.6e-07 29.4 0.2 1.7 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 RLN60240.1 - 3.8e-05 23.9 0.7 0.00019 21.7 0.2 2.5 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II DUF1878 PF08963.10 RLN60240.1 - 0.2 12.2 0.0 0.43 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) Metallophos PF00149.28 RLN60241.1 - 0.00064 20.3 7.1 0.00064 20.3 7.1 2.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase OrfB_Zn_ribbon PF07282.11 RLN60242.1 - 4e-07 29.9 0.4 1.4e-06 28.1 0.4 2.0 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Csm1_N PF18504.1 RLN60242.1 - 0.00028 21.2 3.9 0.0009 19.5 3.9 2.0 1 0 0 1 1 1 1 Csm1 N-terminal domain MbeD_MobD PF04899.12 RLN60242.1 - 0.04 14.0 1.9 0.16 12.1 1.9 2.0 1 1 0 1 1 1 0 MbeD/MobD like HTH_6 PF01418.17 RLN60242.1 - 0.19 11.7 1.0 0.87 9.6 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain, rpiR family DivIC PF04977.15 RLN60242.1 - 0.28 11.0 2.7 0.99 9.2 2.7 2.0 1 0 0 1 1 1 0 Septum formation initiator DUF1640 PF07798.11 RLN60242.1 - 2.8 8.0 8.0 0.35 10.9 2.6 2.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1640) PLATZ PF04640.14 RLN60243.1 - 0.14 12.8 4.8 0.19 12.4 0.6 2.2 2 0 0 2 2 2 0 PLATZ transcription factor Fer4_7 PF12838.7 RLN60243.1 - 0.35 11.5 2.7 21 5.8 1.0 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain WW PF00397.26 RLN60244.1 - 1.1e-08 35.0 4.4 1.6e-08 34.5 3.3 1.8 2 0 0 2 2 2 1 WW domain DUF3053 PF11254.8 RLN60245.1 - 0.011 15.3 0.1 0.016 14.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) PLATZ PF04640.14 RLN60245.1 - 0.58 10.8 5.3 0.23 12.1 0.5 2.3 2 1 0 2 2 2 0 PLATZ transcription factor ODR4-like PF14778.6 RLN60246.1 - 1.1e-31 110.2 0.0 2.8e-31 108.8 0.0 1.7 1 1 0 1 1 1 1 Olfactory receptor 4-like WW PF00397.26 RLN60247.1 - 7.7e-11 41.9 0.0 1.9e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 WW domain Lpp-LpqN PF10738.9 RLN60247.1 - 0.06 12.8 0.2 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Probable lipoprotein LpqN Methyltr_RsmB-F PF01189.17 RLN60249.1 - 2.4e-33 115.5 0.0 1.3e-31 109.8 0.0 2.5 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 RLN60249.1 - 0.0074 16.4 0.0 0.021 14.9 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase Cyto_heme_lyase PF01265.17 RLN60251.1 - 1.1e-51 176.1 7.3 3e-51 174.8 3.4 2.6 2 1 0 2 2 2 1 Cytochrome c/c1 heme lyase Ank_2 PF12796.7 RLN60252.1 - 4.4e-07 30.4 0.1 1.1e-06 29.1 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN60252.1 - 2.3e-05 24.5 0.0 5.5e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN60252.1 - 0.02 15.5 0.2 2.8 8.6 0.1 2.8 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 RLN60252.1 - 0.12 12.9 0.0 0.55 10.8 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat zf-CCCH_4 PF18044.1 RLN60253.1 - 0.028 14.2 3.4 0.053 13.3 3.4 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger Med26 PF08711.11 RLN60253.1 - 0.036 14.1 0.3 0.036 14.1 0.3 2.1 2 0 0 2 2 2 0 TFIIS helical bundle-like domain zf-CCCH PF00642.24 RLN60253.1 - 0.048 13.6 2.1 0.11 12.5 2.1 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 RLN60253.1 - 0.12 13.1 0.1 0.12 13.1 0.1 2.1 2 0 0 2 2 2 0 Torus domain zf_CCCH_4 PF18345.1 RLN60253.1 - 0.2 11.8 4.0 0.41 10.8 4.0 1.6 1 0 0 1 1 1 0 Zinc finger domain DUF572 PF04502.13 RLN60253.1 - 3.1 7.3 13.5 1.1 8.8 8.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) Ribosomal_S6e PF01092.19 RLN60254.1 - 6.5e-57 190.9 0.1 1.2e-56 190.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Myotub-related PF06602.14 RLN60255.1 - 1.4e-102 343.3 0.0 2.1e-100 336.1 0.0 2.2 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 RLN60255.1 - 0.0062 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RLN60255.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 RLN60255.1 - 0.025 14.4 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain CENP-L PF13092.6 RLN60255.1 - 0.071 13.3 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 Thy1 PF02511.15 RLN60277.1 - 0.018 14.8 0.8 0.018 14.8 0.8 1.1 1 0 0 1 1 1 0 Thymidylate synthase complementing protein Thy1 PF02511.15 RLN60278.1 - 0.019 14.8 0.7 0.021 14.7 0.7 1.1 1 0 0 1 1 1 0 Thymidylate synthase complementing protein CAP_GLY PF01302.25 RLN60279.1 - 3.2e-23 81.5 1.6 5.1e-23 80.9 1.6 1.3 1 0 0 1 1 1 1 CAP-Gly domain CLASP_N PF12348.8 RLN60279.1 - 5.4e-22 78.5 0.2 9.4e-22 77.7 0.2 1.4 1 0 0 1 1 1 1 CLASP N terminal Ank_2 PF12796.7 RLN60280.1 - 1.6e-31 108.7 2.9 2.6e-05 24.7 0.0 7.7 4 3 4 8 8 8 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN60280.1 - 1.1e-17 63.8 19.0 0.002 18.4 0.0 10.1 9 1 1 10 10 10 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN60280.1 - 8.4e-13 48.6 14.8 0.014 16.0 0.1 8.9 8 2 3 11 11 11 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN60280.1 - 4.7e-11 41.9 17.4 0.22 12.2 0.1 12.5 12 0 0 12 12 12 1 Ankyrin repeat Ank PF00023.30 RLN60280.1 - 1.9e-10 40.7 32.3 1.1 9.8 0.1 11.5 12 0 0 12 12 12 6 Ankyrin repeat PALP PF00291.25 RLN60300.1 - 1.1e-35 123.5 0.0 1.4e-35 123.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 RLN60300.1 - 2.2e-16 60.1 0.1 2.7e-09 37.4 0.1 3.5 3 0 0 3 3 3 2 CBS domain PfkB PF00294.24 RLN60301.1 - 1.5e-63 214.9 1.4 1.5e-63 214.9 1.4 1.8 2 0 0 2 2 2 1 pfkB family carbohydrate kinase DUF2475 PF10629.9 RLN60301.1 - 0.14 12.4 1.2 28 5.0 0.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2475) E2R135 PF11570.8 RLN60301.1 - 4.4 7.6 8.9 0.48 10.7 2.2 2.5 1 1 1 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 Sec1 PF00995.23 RLN60302.1 - 2e-73 248.5 0.0 2.5e-73 248.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family RRM_1 PF00076.22 RLN60303.1 - 3.4e-34 116.5 0.0 9.9e-16 57.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN60303.1 - 2.5e-13 49.9 0.0 4e-05 23.7 0.0 2.9 2 2 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 RLN60303.1 - 0.0018 18.2 0.0 0.68 10.0 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 RLN60303.1 - 0.025 14.8 0.1 10 6.3 0.0 2.5 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter SPX PF03105.19 RLN60303.1 - 0.29 11.0 3.9 0.42 10.5 3.9 1.3 1 0 0 1 1 1 0 SPX domain Spt20 PF12090.8 RLN60303.1 - 3.9 7.0 10.3 6.3 6.3 10.3 1.2 1 0 0 1 1 1 0 Spt20 family SlyX PF04102.12 RLN60304.1 - 0.075 13.7 0.9 0.075 13.7 0.9 5.1 3 1 3 6 6 6 0 SlyX PAN_4 PF14295.6 RLN60324.1 - 1.3e-13 50.6 17.2 5.6e-09 35.8 3.7 2.7 3 0 0 3 3 3 2 PAN domain PAN_2 PF08276.11 RLN60324.1 - 7.1 6.8 14.3 0.17 12.0 3.4 2.2 2 0 0 2 2 2 0 PAN-like domain RAWUL PF16207.5 RLN60325.1 - 1.1e-08 35.6 0.0 1.7e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like DUF3337 PF11816.8 RLN60325.1 - 8.9e-06 25.7 0.0 1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) MORN PF02493.20 RLN60352.1 - 2.1e-30 102.8 41.4 1.9e-06 27.4 1.2 7.4 7 0 0 7 7 7 7 MORN repeat DUF3048_C PF17479.2 RLN60352.1 - 2 8.8 7.9 9.5 6.7 0.0 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF3048) C-terminal domain Ribosomal_S15 PF00312.22 RLN60353.1 - 2.1e-32 111.1 0.6 3.5e-32 110.4 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PH PF00169.29 RLN60354.1 - 0.071 13.6 0.0 0.074 13.6 0.0 1.1 1 0 0 1 1 1 0 PH domain PAP_RNA-bind PF04926.15 RLN60354.1 - 0.21 11.2 0.0 0.25 10.9 0.0 1.1 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain Nup96 PF12110.8 RLN60355.1 - 1.5e-73 247.5 5.1 2.2e-73 246.9 3.3 2.2 2 0 0 2 2 2 1 Nuclear protein 96 Nucleoporin2 PF04096.14 RLN60355.1 - 8.8e-39 133.0 0.0 1.6e-38 132.1 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Rad60-SLD_2 PF13881.6 RLN60355.1 - 0.0042 17.2 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like N1221 PF07923.13 RLN60355.1 - 0.014 14.6 0.0 0.04 13.1 0.0 1.7 2 0 0 2 2 2 0 N1221-like protein ubiquitin PF00240.23 RLN60355.1 - 0.032 14.0 0.1 0.069 12.9 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin family Nucleoporin2 PF04096.14 RLN60356.1 - 9.1e-30 103.7 0.0 1.4e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Pkinase_Tyr PF07714.17 RLN60375.1 - 8e-53 179.4 0.0 1e-41 143.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN60375.1 - 1.2e-47 162.5 0.0 8.7e-37 126.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Arm PF00514.23 RLN60375.1 - 1.1e-15 57.1 9.9 0.011 15.7 0.0 9.6 10 0 0 10 10 10 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN60375.1 - 9.3e-08 31.7 3.3 7.2 7.2 0.0 6.9 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 RLN60375.1 - 6.7e-06 26.5 22.4 0.01 16.3 0.4 6.7 5 2 3 8 8 8 3 HEAT-like repeat HEAT_2 PF13646.6 RLN60375.1 - 0.001 19.4 28.7 0.28 11.6 1.2 5.8 4 2 1 6 6 6 4 HEAT repeats Kinase-like PF14531.6 RLN60375.1 - 0.0023 17.3 0.0 0.67 9.2 0.0 2.6 2 0 0 2 2 2 2 Kinase-like Succ_CoA_lig PF13607.6 RLN60375.1 - 3.9 7.3 6.3 10 5.9 0.1 3.9 1 1 4 5 5 5 0 Succinyl-CoA ligase like flavodoxin domain HEAT_PBS PF03130.16 RLN60375.1 - 4.3 8.3 24.4 1.1e+02 4.0 0.1 8.7 9 0 0 9 9 9 0 PBS lyase HEAT-like repeat GRIM-19 PF06212.12 RLN60402.1 - 3.2e-32 111.3 0.0 3.8e-32 111.0 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein Glyco_hydro_77 PF02446.17 RLN60402.1 - 0.13 11.1 0.1 0.16 10.7 0.1 1.0 1 0 0 1 1 1 0 4-alpha-glucanotransferase TFIIB PF00382.19 RLN60403.1 - 1.5e-28 98.6 0.1 1.6e-13 50.5 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 RLN60403.1 - 1.6e-08 34.8 1.6 1.6e-08 34.8 1.6 3.6 3 1 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 RLN60403.1 - 1.5e-07 30.8 5.3 4.1e-07 29.4 5.3 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 RLN60403.1 - 0.071 12.9 0.4 4.4 7.1 0.0 3.0 2 1 0 2 2 2 0 Cyclin, N-terminal domain MAPKK1_Int PF08923.10 RLN60403.1 - 0.095 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting zf-RRN7 PF11781.8 RLN60403.1 - 0.28 10.9 1.5 0.64 9.8 1.5 1.6 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 MULE PF10551.9 RLN60404.1 - 0.019 15.3 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 MULE transposase domain Rpn3_C PF08375.11 RLN60405.1 - 4.6e-28 97.4 3.0 9.4e-28 96.4 3.0 1.6 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 RLN60405.1 - 5.9e-22 78.2 3.1 1.7e-20 73.5 0.0 3.2 3 0 0 3 3 3 1 PCI domain TIP120 PF08623.10 RLN60405.1 - 0.14 11.9 5.9 0.049 13.4 2.5 1.9 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) Retrotran_gag_2 PF14223.6 RLN60406.1 - 7.1e-12 45.2 0.0 1.1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 RLN60406.1 - 0.028 14.5 0.5 0.06 13.4 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 RLN60406.1 - 0.2 11.6 1.3 0.45 10.5 1.3 1.6 1 0 0 1 1 1 0 Zinc knuckle Cyclin_N PF00134.23 RLN60407.1 - 5.1e-40 136.1 0.5 5.1e-40 136.1 0.5 2.7 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 RLN60407.1 - 1.9e-16 60.2 0.1 8e-16 58.2 0.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain CcmD PF04995.14 RLN60420.1 - 8.5 6.5 5.8 17 5.6 5.8 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) MULE PF10551.9 RLN60421.1 - 1.9e-08 34.6 0.5 4.2e-08 33.5 0.5 1.6 1 0 0 1 1 1 1 MULE transposase domain WD40 PF00400.32 RLN60424.1 - 6.1e-11 42.7 0.3 0.00015 22.5 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN60424.1 - 1.7e-07 31.4 0.0 0.0028 17.9 0.0 2.6 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN60424.1 - 0.00084 18.4 0.1 0.64 8.9 0.0 2.1 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1064 PF06356.11 RLN60424.1 - 0.01 16.2 0.1 0.015 15.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1064) GSDH PF07995.11 RLN60424.1 - 0.041 13.2 0.0 2.7 7.2 0.0 2.0 1 1 1 2 2 2 0 Glucose / Sorbosone dehydrogenase Proteasome_A_N PF10584.9 RLN60424.1 - 0.16 11.6 0.5 1.1 9.0 0.0 2.5 3 1 0 3 3 3 0 Proteasome subunit A N-terminal signature Pkinase PF00069.25 RLN60425.1 - 1.7e-39 135.8 0.0 2.3e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN60425.1 - 5.2e-18 65.3 0.0 7.6e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN60425.1 - 0.041 13.2 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mtc PF03820.17 RLN60443.1 - 1.4e-54 185.3 0.1 2.4e-54 184.5 0.1 1.4 1 0 0 1 1 1 1 Tricarboxylate carrier UPF0029 PF01205.19 RLN60443.1 - 0.057 13.8 1.0 0.19 12.0 1.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 CbtA PF09490.10 RLN60443.1 - 0.075 12.8 7.5 0.017 14.9 3.0 2.2 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) Pkinase PF00069.25 RLN60461.1 - 2.7e-42 145.0 0.0 3.3e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN60461.1 - 5.9e-28 97.9 0.0 7.2e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN60461.1 - 1.4e-05 24.5 0.0 1.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RLN60461.1 - 0.0013 17.6 0.0 0.0016 17.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase AID PF18767.1 RLN60461.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Activation induced deaminase tRNA_U5-meth_tr PF05958.11 RLN60462.1 - 8.6e-13 48.0 0.0 1.7e-12 47.0 0.0 1.4 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase MTS PF05175.14 RLN60462.1 - 0.00067 19.2 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 RLN60462.1 - 0.0017 18.1 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltrans_SAM PF10672.9 RLN60462.1 - 0.0023 17.2 0.5 0.013 14.7 0.2 2.4 2 1 0 2 2 2 1 S-adenosylmethionine-dependent methyltransferase Methyltransf_31 PF13847.6 RLN60462.1 - 0.0038 17.0 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN60462.1 - 0.035 14.8 0.0 0.11 13.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 RLN60462.1 - 0.067 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 RLN60462.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PNRC PF15365.6 RLN60462.1 - 0.15 11.9 3.8 0.61 10.0 3.8 2.1 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif DUF5400 PF17379.2 RLN60463.1 - 0.16 12.5 0.3 0.16 12.5 0.3 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5400) Pkinase PF00069.25 RLN60464.1 - 7.1e-39 133.8 0.0 9.6e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN60464.1 - 1.5e-24 86.6 0.0 2.1e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN60464.1 - 5.5e-05 22.6 0.2 0.00023 20.6 0.0 2.0 1 1 2 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN60464.1 - 0.00022 21.2 0.1 0.00036 20.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RLN60464.1 - 0.003 16.9 0.0 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RLN60464.1 - 0.052 12.3 0.0 0.087 11.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF4096 PF13340.6 RLN60464.1 - 0.17 12.2 3.5 21 5.4 0.2 3.5 3 0 0 3 3 3 0 Putative transposase of IS4/5 family (DUF4096) TCR PF03638.15 RLN60465.1 - 4.4e-13 49.3 22.1 8e-13 48.5 22.1 1.4 1 0 0 1 1 1 1 Tesmin/TSO1-like CXC domain, cysteine-rich domain TSC22 PF01166.18 RLN60465.1 - 0.057 13.7 0.1 0.14 12.5 0.1 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family RNase_PH PF01138.21 RLN60466.1 - 7.6e-19 68.5 0.1 2.3e-18 66.9 0.1 1.9 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 TCR PF03638.15 RLN60466.1 - 5.5e-07 29.8 19.6 9.4e-07 29.0 19.6 1.4 1 0 0 1 1 1 1 Tesmin/TSO1-like CXC domain, cysteine-rich domain RNase_PH_C PF03725.15 RLN60466.1 - 0.0021 18.1 0.1 0.0039 17.2 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 CNRIP1 PF15043.6 RLN60466.1 - 0.01 15.4 0.0 0.027 14.0 0.0 1.6 2 0 0 2 2 2 0 CB1 cannabinoid receptor-interacting protein 1 E1-E2_ATPase PF00122.20 RLN60479.1 - 6.8e-43 146.3 13.3 4.1e-30 104.7 0.2 3.5 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 RLN60479.1 - 6.2e-38 130.3 0.8 6.2e-38 130.3 0.8 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 RLN60479.1 - 1.4e-17 64.7 7.4 9.1e-16 58.8 5.0 3.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN60479.1 - 4.7e-16 58.6 0.0 1.6e-15 57.0 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 RLN60479.1 - 2.1e-15 56.1 0.0 4.6e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RLN60479.1 - 0.0028 17.5 0.4 0.0051 16.6 0.4 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 RLN60479.1 - 0.033 14.6 0.1 0.18 12.2 0.1 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DDOST_48kD PF03345.14 RLN60479.1 - 0.17 10.6 0.1 0.37 9.6 0.1 1.5 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta SWIM PF04434.17 RLN60480.1 - 5.4e-07 29.2 0.5 1.7e-06 27.6 0.5 1.9 1 0 0 1 1 1 1 SWIM zinc finger DBD_Tnp_Mut PF03108.15 RLN60480.1 - 0.063 13.3 0.1 0.17 11.9 0.1 1.8 1 0 0 1 1 1 0 MuDR family transposase MULE PF10551.9 RLN60480.1 - 0.12 12.8 0.0 9.4 6.7 0.0 3.0 3 0 0 3 3 3 0 MULE transposase domain adh_short PF00106.25 RLN60481.1 - 4e-46 157.0 1.5 4.9e-46 156.7 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN60481.1 - 1.7e-32 112.8 2.1 2.3e-32 112.5 2.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN60481.1 - 2.7e-18 66.5 6.1 7.9e-17 61.7 3.0 2.1 2 0 0 2 2 2 2 KR domain NAD_binding_10 PF13460.6 RLN60481.1 - 1.6e-05 24.9 0.1 2.8e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 RLN60481.1 - 0.013 14.7 0.1 0.022 13.9 0.1 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.21 RLN60481.1 - 0.023 14.2 0.2 0.031 13.7 0.2 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 7tm_6 PF02949.20 RLN60482.1 - 0.027 13.6 2.7 0.11 11.6 0.1 2.9 3 0 0 3 3 3 0 7tm Odorant receptor UbiA PF01040.18 RLN60482.1 - 0.052 12.8 0.1 0.052 12.8 0.1 3.2 2 1 1 3 3 3 0 UbiA prenyltransferase family PEMT PF04191.13 RLN60482.1 - 0.082 13.3 0.4 0.082 13.3 0.4 2.5 3 0 0 3 3 3 0 Phospholipid methyltransferase Orf78 PF06024.12 RLN60482.1 - 0.2 12.0 1.2 27 5.1 0.0 3.7 4 0 0 4 4 4 0 Orf78 (ac78) Herpes_LMP1 PF05297.11 RLN60482.1 - 0.21 10.8 5.5 0.13 11.4 0.5 2.1 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) 2OG-FeII_Oxy_3 PF13640.6 RLN60516.1 - 2.5e-10 41.1 0.1 3.4e-10 40.7 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 RLN60516.1 - 2.7e-06 27.8 0.0 3.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 RLN60516.1 - 0.003 18.2 0.0 0.0044 17.7 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AAA_2 PF07724.14 RLN60518.1 - 2e-52 177.8 6.7 1.3e-50 171.8 0.0 3.8 4 0 0 4 4 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 RLN60518.1 - 4.1e-35 119.8 2.7 4.1e-35 119.8 2.7 3.3 3 1 0 3 3 2 1 AAA lid domain AAA PF00004.29 RLN60518.1 - 3.7e-27 95.4 0.7 1.6e-13 51.2 0.0 3.3 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 RLN60518.1 - 7.2e-21 74.0 1.7 2e-20 72.6 0.2 2.7 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 RLN60518.1 - 2.3e-19 69.8 0.8 3.8e-13 49.6 0.0 3.8 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 RLN60518.1 - 2.5e-14 53.1 8.8 1.1e-06 28.6 0.0 3.8 4 0 0 4 4 3 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 RLN60518.1 - 1e-10 42.3 11.0 7.8e-06 26.4 0.1 5.0 3 3 0 4 4 3 2 AAA ATPase domain Sigma54_activat PF00158.26 RLN60518.1 - 5.5e-10 39.2 0.0 3e-07 30.3 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 RLN60518.1 - 6e-10 39.5 5.7 0.0013 19.0 0.0 5.2 2 2 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 RLN60518.1 - 4.3e-08 33.1 0.0 0.0014 18.4 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_14 PF13173.6 RLN60518.1 - 1.3e-07 31.7 0.0 0.024 14.7 0.0 3.6 4 0 0 4 4 2 2 AAA domain AAA_7 PF12775.7 RLN60518.1 - 9.5e-07 28.5 0.0 0.0094 15.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region RuvB_N PF05496.12 RLN60518.1 - 8.2e-06 25.6 2.2 0.23 11.2 0.0 4.5 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 RLN60518.1 - 8.9e-06 25.2 3.7 0.013 14.9 0.1 4.5 3 1 0 3 3 3 1 Bacterial TniB protein ATPase_2 PF01637.18 RLN60518.1 - 1.8e-05 24.8 11.1 0.43 10.4 0.1 4.9 4 1 1 5 5 5 3 ATPase domain predominantly from Archaea AAA_3 PF07726.11 RLN60518.1 - 1.9e-05 24.5 0.4 0.0083 16.0 0.0 3.6 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 RLN60518.1 - 2.8e-05 23.8 0.1 0.02 14.4 0.0 3.8 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 RLN60518.1 - 3e-05 23.5 0.1 0.54 9.6 0.0 3.8 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 RLN60518.1 - 9.9e-05 22.9 5.7 0.12 13.0 0.0 4.5 5 1 0 5 5 3 1 AAA domain Roc PF08477.13 RLN60518.1 - 0.00012 22.3 0.0 0.36 11.0 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 RLN60518.1 - 0.00021 21.3 0.0 0.46 10.4 0.0 2.9 2 0 0 2 2 2 2 NACHT domain DNA_pol3_delta2 PF13177.6 RLN60518.1 - 0.00043 20.1 0.0 0.015 15.1 0.0 2.9 1 1 0 1 1 1 1 DNA polymerase III, delta subunit RNA_helicase PF00910.22 RLN60518.1 - 0.0005 20.4 0.0 0.81 10.1 0.0 3.1 3 0 0 3 3 2 1 RNA helicase RsgA_GTPase PF03193.16 RLN60518.1 - 0.00076 19.4 0.2 1.8 8.4 0.0 3.2 3 0 0 3 3 2 2 RsgA GTPase AAA_28 PF13521.6 RLN60518.1 - 0.00084 19.6 11.2 3.6 7.8 0.0 5.8 6 2 0 6 6 5 1 AAA domain TsaE PF02367.17 RLN60518.1 - 0.00087 19.3 0.0 2 8.4 0.0 3.1 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 RLN60518.1 - 0.00098 18.5 0.4 0.073 12.3 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin AAA_33 PF13671.6 RLN60518.1 - 0.0011 19.2 0.3 0.84 9.8 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.6 RLN60518.1 - 0.0044 17.5 19.8 0.019 15.5 0.0 3.9 2 2 0 2 2 1 1 AAA domain AAA_24 PF13479.6 RLN60518.1 - 0.0048 16.6 0.0 3.4 7.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 RLN60518.1 - 0.0053 16.8 0.0 0.71 9.9 0.0 3.7 4 0 0 4 4 3 1 Type III restriction enzyme, res subunit ABC_tran PF00005.27 RLN60518.1 - 0.0064 17.0 2.5 0.77 10.3 0.0 3.9 3 1 0 3 3 3 1 ABC transporter AAA_29 PF13555.6 RLN60518.1 - 0.015 15.0 0.0 6 6.7 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain HEPN_Swt1 PF18731.1 RLN60518.1 - 0.068 13.5 3.0 0.32 11.3 2.3 2.5 2 0 0 2 2 2 0 Swt1-like HEPN DUF87 PF01935.17 RLN60518.1 - 0.071 13.2 10.4 0.33 11.0 0.0 4.1 5 0 0 5 5 4 0 Helicase HerA, central domain NTPase_1 PF03266.15 RLN60518.1 - 0.15 12.0 1.4 17 5.3 0.0 3.8 4 0 0 4 4 3 0 NTPase AAA_19 PF13245.6 RLN60518.1 - 0.2 12.0 6.5 1 9.7 0.1 4.6 5 1 0 5 5 5 0 AAA domain AbLIM_anchor PF16182.5 RLN60518.1 - 0.23 11.3 1.6 0.41 10.4 1.6 1.3 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM UvrD-helicase PF00580.21 RLN60518.1 - 2.6 7.5 11.4 0.81 9.1 6.0 2.6 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain WW PF00397.26 RLN60519.1 - 8.2e-07 29.0 4.3 1.7e-06 28.0 4.3 1.6 1 0 0 1 1 1 1 WW domain RWP-RK PF02042.15 RLN60520.1 - 4.1e-21 74.7 0.1 9e-21 73.6 0.1 1.6 1 0 0 1 1 1 1 RWP-RK domain Rtf2 PF04641.12 RLN60521.1 - 0.033 13.5 0.0 0.033 13.5 0.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_2 PF13639.6 RLN60521.1 - 0.042 14.2 0.2 0.062 13.7 0.2 1.2 1 0 0 1 1 1 0 Ring finger domain DiS_P_DiS PF06750.13 RLN60521.1 - 0.068 13.3 0.0 0.096 12.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain zf-rbx1 PF12678.7 RLN60521.1 - 0.1 12.9 0.2 0.15 12.4 0.2 1.3 1 0 0 1 1 1 0 RING-H2 zinc finger domain Rad50_zn_hook PF04423.14 RLN60521.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Rad50 zinc hook motif ALG11_N PF15924.5 RLN60522.1 - 4e-74 249.2 0.2 5.6e-74 248.7 0.2 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 RLN60522.1 - 1.4e-26 93.1 0.0 2.8e-26 92.1 0.0 1.5 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RLN60522.1 - 1.2e-16 61.4 0.0 2.4e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 RLN60522.1 - 0.00057 20.2 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 FHA PF00498.26 RLN60523.1 - 1e-28 99.5 0.7 5.5e-15 55.5 0.0 2.4 2 0 0 2 2 2 2 FHA domain Yop-YscD_cpl PF16697.5 RLN60523.1 - 6e-16 58.5 0.0 3.8e-07 30.3 0.0 2.4 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain Intein_splicing PF14890.6 RLN60524.1 - 0.00059 19.8 0.0 0.0036 17.2 0.0 2.5 2 1 0 2 2 2 1 Intein splicing domain E1-E2_ATPase PF00122.20 RLN60525.1 - 4e-49 166.6 4.0 4.2e-48 163.2 2.3 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 RLN60525.1 - 2.9e-35 121.6 16.3 2.4e-18 66.5 0.0 3.9 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 RLN60525.1 - 1.7e-25 88.9 0.1 3.8e-25 87.8 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RLN60525.1 - 9.5e-20 71.8 0.1 3.1e-09 37.4 0.0 3.6 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RLN60525.1 - 1.5e-12 47.0 0.0 3.1e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RLN60525.1 - 0.00015 21.6 2.5 0.0052 16.6 0.5 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Enolase_C PF00113.22 RLN60526.1 - 6e-31 107.8 0.0 1.3e-18 67.3 0.0 2.9 2 1 0 2 2 2 2 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 RLN60526.1 - 1.8e-08 34.6 0.1 6.2e-08 32.9 0.1 1.9 2 0 0 2 2 2 1 Enolase, N-terminal domain FYVE PF01363.21 RLN60587.1 - 0.055 13.6 20.4 0.15 12.2 20.4 1.7 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN60587.1 - 1.9 8.7 18.4 15 5.9 18.5 2.2 1 1 1 2 2 2 0 FYVE-type zinc finger Siva PF05458.12 RLN60587.1 - 2.4 7.8 18.4 5.1 6.8 18.4 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) FYVE PF01363.21 RLN60588.1 - 0.00024 21.2 15.1 0.00071 19.7 15.1 1.8 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN60588.1 - 0.00029 21.0 11.5 0.00084 19.6 11.1 2.0 1 1 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 RLN60589.1 - 1.3 9.2 17.9 0.59 10.3 15.6 1.7 1 1 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN60589.1 - 8.3 6.7 14.9 42 4.4 14.8 2.2 1 1 0 1 1 1 0 FYVE-type zinc finger IQ PF00612.27 RLN60607.1 - 0.001 18.7 2.1 0.0019 17.8 2.1 1.4 1 0 0 1 1 1 1 IQ calmodulin-binding motif Myotub-related PF06602.14 RLN60608.1 - 1.8e-113 379.1 0.2 3.1e-113 378.3 0.1 1.4 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain Vps36_ESCRT-II PF11605.8 RLN60608.1 - 0.0066 16.6 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Y_phosphatase3 PF13350.6 RLN60608.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PH_TFIIH PF08567.11 RLN60608.1 - 0.094 13.1 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain VPS13_C PF16909.5 RLN60608.1 - 0.25 11.1 3.5 0.44 10.3 3.5 1.3 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal FAD_binding_2 PF00890.24 RLN60609.1 - 0.065 12.3 0.1 0.068 12.2 0.1 1.0 1 0 0 1 1 1 0 FAD binding domain MIase PF02426.16 RLN60609.1 - 0.086 13.0 0.2 0.11 12.6 0.2 1.2 1 0 0 1 1 1 0 Muconolactone delta-isomerase UPF0176_N PF17773.1 RLN60610.1 - 1.4e-21 76.7 0.1 4.2e-21 75.1 0.0 1.9 2 0 0 2 2 2 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 RLN60610.1 - 1.8e-09 38.1 0.0 3.5e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain FYVE PF01363.21 RLN60610.1 - 0.0079 16.3 7.7 0.63 10.2 0.1 2.6 2 0 0 2 2 2 2 FYVE zinc finger zf-P11 PF03854.14 RLN60610.1 - 0.065 12.9 6.4 0.035 13.8 3.6 2.0 1 1 0 1 1 1 0 P-11 zinc finger DUF4554 PF15091.6 RLN60610.1 - 0.13 11.1 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Rhodanese_C PF12368.8 RLN60610.1 - 0.94 9.9 20.1 0.063 13.6 10.3 2.8 2 1 0 2 2 2 0 Rhodanase C-terminal Retrotran_gag_2 PF14223.6 RLN60612.1 - 7.3e-10 38.7 0.0 1.1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 RLN60612.1 - 0.0042 17.1 2.9 0.011 15.8 2.9 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 RLN60612.1 - 0.0054 16.5 3.6 0.01 15.6 3.6 1.5 1 0 0 1 1 1 1 Zinc knuckle NmrA PF05368.13 RLN60638.1 - 3e-11 43.3 0.0 3.3e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 RLN60638.1 - 1.4e-07 31.6 0.0 1.6e-07 31.4 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 RLN60638.1 - 7.7e-07 29.4 0.0 8.8e-07 29.2 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 RLN60638.1 - 9.3e-07 28.6 0.1 1.4e-06 28.0 0.1 1.3 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 RLN60638.1 - 5.9e-06 25.7 0.0 7.1e-06 25.5 0.0 1.0 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 RLN60638.1 - 6.8e-06 26.3 0.0 7.3e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 RLN60638.1 - 0.00021 21.4 0.0 0.00024 21.2 0.0 1.0 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 RLN60638.1 - 0.00024 20.4 0.1 0.00027 20.3 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 RLN60638.1 - 0.00032 21.1 0.1 0.00039 20.8 0.1 1.1 1 0 0 1 1 1 1 Putative NAD(P)-binding PglD_N PF17836.1 RLN60638.1 - 0.0006 20.4 0.0 0.00072 20.1 0.0 1.1 1 0 0 1 1 1 1 PglD N-terminal domain Epimerase PF01370.21 RLN60638.1 - 0.0014 18.2 0.0 0.0017 17.9 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 RLN60638.1 - 0.0018 17.8 0.1 0.0022 17.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Pyr_redox_3 PF13738.6 RLN60638.1 - 0.003 16.9 0.0 0.003 16.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 RLN60638.1 - 0.0046 17.1 0.0 0.0051 17.0 0.0 1.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.27 RLN60638.1 - 0.0091 16.5 0.1 0.012 16.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Ldh_1_N PF00056.23 RLN60638.1 - 0.011 15.8 0.0 0.014 15.5 0.0 1.0 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.17 RLN60638.1 - 0.012 16.2 0.1 0.015 15.8 0.1 1.2 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 RLN60638.1 - 0.013 15.1 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 RLN60638.1 - 0.022 14.6 0.1 0.024 14.5 0.1 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 RLN60638.1 - 0.023 14.1 0.1 0.028 13.8 0.1 1.2 1 0 0 1 1 1 0 ThiF family KR PF08659.10 RLN60638.1 - 0.029 14.3 0.0 0.033 14.1 0.0 1.1 1 0 0 1 1 1 0 KR domain Pyr_redox_2 PF07992.14 RLN60638.1 - 0.041 13.1 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_trans_4_5 PF16994.5 RLN60638.1 - 0.044 13.4 0.0 0.052 13.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl-transferase family 4 TMEM100 PF16311.5 RLN60638.1 - 0.058 13.0 0.0 0.067 12.8 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 100 GDP_Man_Dehyd PF16363.5 RLN60638.1 - 0.062 12.7 0.0 0.068 12.6 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_8 PF13450.6 RLN60638.1 - 0.07 13.4 0.5 0.11 12.8 0.5 1.3 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain adh_short_C2 PF13561.6 RLN60638.1 - 0.07 12.7 0.1 0.087 12.4 0.1 1.0 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase GFO_IDH_MocA PF01408.22 RLN60638.1 - 0.1 13.4 0.0 0.12 13.2 0.0 1.0 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold UDPG_MGDP_dh_N PF03721.14 RLN60638.1 - 0.13 11.8 0.3 0.2 11.2 0.3 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.12 RLN60638.1 - 0.14 11.8 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NmrA PF05368.13 RLN60639.1 - 6.5e-07 29.1 0.1 5.5e-06 26.1 0.1 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 RLN60639.1 - 3.2e-05 23.9 0.1 0.034 14.0 0.2 2.2 2 0 0 2 2 2 2 NAD(P)H-binding ApbA PF02558.16 RLN60639.1 - 4.4e-05 23.2 0.9 9.5e-05 22.1 0.7 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 RLN60639.1 - 0.00031 20.1 0.5 0.00044 19.6 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Sacchrp_dh_NADP PF03435.18 RLN60639.1 - 0.00052 20.3 0.5 0.0048 17.2 0.4 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 RLN60639.1 - 0.0011 19.2 0.4 0.0052 17.0 0.1 1.9 2 0 0 2 2 2 1 TrkA-N domain Shikimate_DH PF01488.20 RLN60639.1 - 0.0025 17.9 0.0 0.0043 17.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 RLN60639.1 - 0.0035 17.9 0.4 0.0064 17.0 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 RLN60639.1 - 0.0085 16.5 0.0 0.013 15.9 0.0 1.4 1 1 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 RLN60639.1 - 0.011 15.0 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 RLN60639.1 - 0.011 14.9 0.1 0.016 14.5 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 RLN60639.1 - 0.03 13.9 0.2 0.055 13.0 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PglD_N PF17836.1 RLN60639.1 - 0.041 14.5 0.1 0.075 13.7 0.1 1.4 1 0 0 1 1 1 0 PglD N-terminal domain ThiF PF00899.21 RLN60639.1 - 0.05 12.9 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 ThiF family DAO PF01266.24 RLN60639.1 - 0.06 12.9 0.2 0.062 12.9 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 RLN60639.1 - 0.081 12.2 2.5 0.33 10.2 2.3 2.0 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 RLN60639.1 - 0.099 12.1 0.2 0.19 11.2 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase F420_oxidored PF03807.17 RLN60639.1 - 0.1 13.2 0.2 0.22 12.1 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.6 RLN60639.1 - 0.12 12.7 0.6 0.22 11.8 0.6 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 RLN60639.1 - 0.24 11.3 1.1 0.41 10.5 1.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Nicastrin PF05450.15 RLN60643.1 - 9.7e-17 61.2 0.2 2.2e-15 56.8 0.2 2.2 1 1 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.17 RLN60643.1 - 3e-07 30.3 0.2 1.1e-06 28.5 0.2 2.1 1 1 0 1 1 1 1 Peptidase family M28 Bax1-I PF01027.20 RLN60644.1 - 0.0087 15.9 37.2 0.011 15.6 37.2 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 NBP1 PF08537.10 RLN60644.1 - 0.11 11.8 0.1 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 FYVE PF01363.21 RLN60645.1 - 6.7e-10 39.0 15.6 1.2e-09 38.1 15.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN60645.1 - 0.0013 18.9 4.8 0.0023 18.1 4.8 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger Bd3614-deam PF14439.6 RLN60645.1 - 0.0048 17.0 0.6 0.012 15.7 0.6 1.6 1 0 0 1 1 1 1 Bd3614-like deaminase Ta0938 PF11494.8 RLN60645.1 - 0.18 12.1 2.2 0.38 11.1 2.2 1.4 1 0 0 1 1 1 0 Ta0938 GET2 PF08690.10 RLN60645.1 - 0.26 10.9 2.6 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 GET complex subunit GET2 TMEM171 PF15471.6 RLN60645.1 - 7.6 5.4 6.3 1.7 7.5 2.0 2.0 2 0 0 2 2 2 0 Transmembrane protein family 171 ACOX PF01756.19 RLN60652.1 - 1e-46 158.8 0.1 1.6e-46 158.1 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 RLN60652.1 - 4.7e-21 75.6 0.6 8.6e-21 74.8 0.6 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 RLN60652.1 - 1.9e-10 40.8 0.0 4.1e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Ank_4 PF13637.6 RLN60686.1 - 1.4e-36 124.3 25.8 1.9e-06 28.3 0.1 11.6 5 3 7 12 12 12 11 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN60686.1 - 5.1e-35 119.9 6.4 2.2e-07 31.3 0.1 7.2 2 2 6 9 9 9 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN60686.1 - 1.3e-25 89.1 23.6 0.064 13.6 0.3 14.3 5 3 11 16 16 16 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN60686.1 - 7.3e-18 62.8 8.8 4.6 8.1 0.0 14.4 15 1 1 16 16 16 3 Ankyrin repeat DUF1843 PF08898.10 RLN60686.1 - 1.7e-06 28.4 12.6 6.2 7.4 0.1 8.9 8 1 1 9 9 9 2 Domain of unknown function (DUF1843) Ank PF00023.30 RLN60686.1 - 8.6e-06 26.0 0.9 60 4.3 0.0 8.8 5 3 3 8 8 8 0 Ankyrin repeat HA PF03457.14 RLN60686.1 - 0.00019 21.7 1.1 1.6 9.1 0.0 5.5 2 2 0 3 3 3 1 Helicase associated domain AbiEi_3_N PF17194.4 RLN60686.1 - 0.01 15.9 0.2 4.1 7.5 0.0 4.9 5 1 2 7 7 7 1 Transcriptional regulator, AbiEi antitoxin N-terminal domain LCIB_C_CA PF18599.1 RLN60721.1 - 0.027 13.8 7.6 0.024 13.9 6.8 1.3 1 1 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF3776 PF12618.8 RLN60721.1 - 0.15 12.6 8.1 0.068 13.7 5.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3776) DDE_Tnp_4 PF13359.6 RLN60722.1 - 6.1e-09 35.7 0.0 9.2e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Aconitase PF00330.20 RLN60735.1 - 1.6e-70 238.4 0.2 1.1e-68 232.4 0.2 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 RLN60735.1 - 5.7e-17 62.3 0.0 1.1e-16 61.4 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain FLYWCH_u PF16662.5 RLN60736.1 - 0.022 14.8 1.4 0.035 14.1 0.2 2.1 2 0 0 2 2 2 0 FLYWCH-type zinc finger-containing protein 1 Aa_trans PF01490.18 RLN60737.1 - 1.1e-59 202.2 26.7 1.3e-59 202.0 26.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1240 PF06836.12 RLN60737.1 - 0.066 13.8 7.3 0.14 12.7 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) AAA_18 PF13238.6 RLN60738.1 - 1.4e-15 58.0 0.0 2.2e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 RLN60738.1 - 0.064 13.1 0.0 0.097 12.5 0.0 1.3 1 1 0 1 1 1 0 Deoxynucleoside kinase Tub PF01167.18 RLN60798.1 - 3.4e-43 148.1 0.2 2.4e-42 145.4 0.2 2.0 1 1 0 1 1 1 1 Tub family CDC45 PF02724.14 RLN60798.1 - 0.36 9.1 6.6 0.43 8.8 6.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Ank_2 PF12796.7 RLN60799.1 - 8e-11 42.4 0.1 1.2e-09 38.6 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN60799.1 - 4e-09 36.6 0.1 0.0044 17.3 0.0 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN60799.1 - 1.9e-07 31.5 0.1 1.4e-06 28.8 0.0 2.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 RLN60799.1 - 4.4e-07 30.1 0.3 0.0013 19.1 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 RLN60799.1 - 6.8e-07 29.1 0.0 0.007 16.8 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat ADH_N PF08240.12 RLN60800.1 - 3.6e-25 88.0 1.4 3.6e-25 88.0 1.4 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN60800.1 - 1e-16 61.1 0.0 1.6e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN60800.1 - 0.00029 20.3 0.0 0.00043 19.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 RLN60800.1 - 0.00031 21.8 0.0 0.0005 21.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 RLN60800.1 - 0.033 13.5 0.2 0.053 12.8 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain YihI PF04220.12 RLN60801.1 - 0.11 12.2 0.4 1.6 8.4 0.1 2.3 2 0 0 2 2 2 0 Der GTPase activator (YihI) ACT_4 PF13291.6 RLN60801.1 - 0.11 13.1 0.7 24 5.6 0.1 2.5 2 0 0 2 2 2 0 ACT domain eIF3_N PF09440.10 RLN60874.1 - 0.1 13.1 6.7 0.089 13.2 4.8 1.9 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain Spec3 PF15795.5 RLN60874.1 - 0.13 12.9 0.2 0.53 10.9 0.0 2.0 2 0 0 2 2 2 0 Ectodermal ciliogenesis protein Allexi_40kDa PF05549.11 RLN60874.1 - 0.65 9.5 2.8 1.6 8.2 1.9 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein mRNA_cap_enzyme PF01331.19 RLN60879.1 - 1.1e-20 74.4 0.0 1.4e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.21 RLN60879.1 - 0.0034 17.0 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DUF3584 PF12128.8 RLN60880.1 - 0.016 12.8 24.2 0.039 11.5 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Orthopox_35kD PF02250.15 RLN60880.1 - 0.045 13.4 0.2 0.079 12.6 0.2 1.4 1 1 0 1 1 1 0 35kD major secreted virus protein SelB-wing_1 PF09105.10 RLN60880.1 - 0.099 12.6 0.4 0.34 10.9 0.4 1.9 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Golgin_A5 PF09787.9 RLN60880.1 - 1.3 8.4 27.6 1.2 8.6 0.8 2.9 2 1 0 2 2 2 0 Golgin subfamily A member 5 OSCP PF00213.18 RLN60880.1 - 4.1 7.5 15.3 0.39 10.8 0.2 3.6 2 1 2 4 4 4 0 ATP synthase delta (OSCP) subunit Flagellin_N PF00669.20 RLN60880.1 - 4.1 7.5 12.3 4 7.6 0.3 2.8 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region Cwf_Cwc_15 PF04889.12 RLN60881.1 - 2.1 8.0 8.7 1.7 8.3 5.1 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF3246 PF11596.8 RLN60881.1 - 7.4 5.9 11.1 14 5.0 11.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) SR-25 PF10500.9 RLN60904.1 - 0.28 10.8 5.5 0.46 10.0 5.5 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 RLN60905.1 - 1e-25 90.6 0.0 1.6e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN60905.1 - 7.1e-14 51.7 0.0 1.1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN60905.1 - 2.3e-05 23.9 0.0 3.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 RLN60905.1 - 0.0041 16.7 0.1 0.0065 16.1 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 RLN60905.1 - 0.017 15.1 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN60905.1 - 0.019 13.9 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DnaJ PF00226.31 RLN60906.1 - 1.4e-18 66.8 0.1 3.5e-18 65.5 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 RLN60906.1 - 0.00017 20.8 0.0 0.00086 18.5 0.0 1.8 1 1 0 1 1 1 1 Sec63 Brl domain Monooxygenase_B PF04744.12 RLN60906.1 - 0.2 10.5 0.0 4.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Monooxygenase subunit B protein DELLA PF12041.8 RLN60908.1 - 0.0014 18.4 0.6 0.08 12.8 0.1 2.6 2 0 0 2 2 2 1 Transcriptional regulator DELLA protein N terminal Cep57_MT_bd PF06657.13 RLN60908.1 - 0.34 11.4 0.2 0.34 11.4 0.2 3.4 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 CAP_N PF01213.19 RLN60908.1 - 3.2 7.1 8.8 2.6 7.4 2.1 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF1690 PF07956.11 RLN60908.1 - 5.1 7.5 7.7 7.2 7.0 1.5 3.0 3 1 1 4 4 4 0 Protein of Unknown function (DUF1690) Ank_2 PF12796.7 RLN60910.1 - 4.3e-28 97.7 2.3 6e-10 39.6 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN60910.1 - 3.4e-23 81.7 1.7 2.9e-07 30.9 0.1 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN60910.1 - 9.6e-21 71.7 1.2 3.3e-05 23.9 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 RLN60910.1 - 7.8e-20 70.7 6.3 2.6e-06 27.6 0.0 4.9 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN60910.1 - 2e-16 59.6 8.9 6.8e-06 26.3 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat PseudoU_synth_2 PF00849.22 RLN60911.1 - 2.8e-18 66.5 0.0 6.5e-18 65.3 0.0 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase GTP_EFTU PF00009.27 RLN60912.1 - 1.9e-19 70.0 0.2 2.3e-19 69.7 0.2 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain NUDIX PF00293.28 RLN60913.1 - 6.2e-14 52.2 0.2 1.1e-13 51.3 0.2 1.4 1 0 0 1 1 1 1 NUDIX domain DnaJ PF00226.31 RLN60914.1 - 3.1e-10 40.0 0.1 5.6e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Phage_GPD PF05954.11 RLN60914.1 - 0.14 11.4 3.3 0.17 11.1 3.3 1.1 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) RIC3 PF15361.6 RLN60914.1 - 0.27 11.6 1.2 1.2 9.5 0.0 2.1 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 ANAPC4_WD40 PF12894.7 RLN60947.1 - 1.6e-10 41.1 0.1 0.00025 21.3 0.0 5.4 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 RLN60947.1 - 6e-10 39.2 10.5 0.046 13.6 0.1 6.6 3 1 2 6 6 6 3 Region in Clathrin and VPS TPR_14 PF13428.6 RLN60947.1 - 3.3e-08 33.7 25.6 0.015 16.0 0.0 9.7 10 1 0 10 10 9 2 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 RLN60947.1 - 6.8e-08 32.0 6.5 0.058 12.4 0.6 4.6 4 1 0 4 4 4 3 Coatomer WD associated region SNAP PF14938.6 RLN60947.1 - 2.6e-07 30.4 27.8 0.0017 17.8 6.3 4.7 3 1 1 4 4 4 3 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 RLN60947.1 - 2.2e-06 27.4 27.2 0.069 13.3 0.3 10.0 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN60947.1 - 3.2e-06 26.8 22.5 0.015 15.3 0.1 8.7 9 1 1 10 10 9 2 Tetratricopeptide repeat WD40 PF00400.32 RLN60947.1 - 0.0015 19.3 0.1 6.7 7.8 0.0 5.8 7 0 0 7 7 6 1 WD domain, G-beta repeat TPR_11 PF13414.6 RLN60947.1 - 0.0018 17.9 12.0 0.75 9.5 0.2 5.5 6 0 0 6 6 6 2 TPR repeat TPR_12 PF13424.6 RLN60947.1 - 0.0028 17.9 1.6 0.0028 17.9 1.6 6.7 8 1 0 8 8 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN60947.1 - 0.0037 17.7 27.1 12 6.5 0.1 10.2 7 3 5 12 12 12 0 Tetratricopeptide repeat RPN7 PF10602.9 RLN60947.1 - 0.0073 16.0 18.2 0.036 13.8 0.2 6.7 5 2 1 6 6 6 1 26S proteasome subunit RPN7 Vps39_1 PF10366.9 RLN60947.1 - 0.0084 16.4 0.2 0.43 10.9 0.1 3.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 TPR_8 PF13181.6 RLN60947.1 - 0.0089 16.2 20.7 0.047 13.9 0.4 8.0 10 1 1 11 11 9 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN60947.1 - 0.11 12.4 30.3 1 9.3 0.3 7.8 9 0 0 9 9 8 0 Tetratricopeptide repeat PPR_2 PF13041.6 RLN60947.1 - 0.65 10.2 5.7 1.5 9.1 0.1 4.2 4 0 0 4 4 4 0 PPR repeat family PPR PF01535.20 RLN60947.1 - 1.1 9.6 11.7 12 6.4 0.2 6.2 7 0 0 7 7 6 0 PPR repeat ANAPC3 PF12895.7 RLN60947.1 - 2.8 8.2 21.1 2.5 8.4 0.2 7.1 4 3 2 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 RLN60947.1 - 3.4 8.5 27.7 6.3 7.7 0.1 8.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN60947.1 - 5.2 7.1 16.2 0.5 10.3 0.5 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 RLN60947.1 - 8.8 6.5 17.2 2 8.5 0.1 5.9 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain CPL PF08144.11 RLN60948.1 - 1.2e-15 58.1 5.6 5.1e-12 46.3 0.2 5.0 3 3 2 5 5 5 2 CPL (NUC119) domain PUF PF00806.19 RLN60948.1 - 4e-09 35.7 0.3 0.00067 19.2 0.0 5.3 5 0 0 5 5 5 2 Pumilio-family RNA binding repeat DUF4071 PF13281.6 RLN60948.1 - 0.0049 16.0 1.8 0.0049 16.0 1.8 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4071) Helicase_C_2 PF13307.6 RLN60949.1 - 9.1e-53 178.9 0.4 2e-40 138.8 0.0 2.6 2 0 0 2 2 2 2 Helicase C-terminal domain DEAD_2 PF06733.15 RLN60949.1 - 9.4e-51 171.9 0.3 1.6e-50 171.2 0.3 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 RLN60949.1 - 0.0013 18.7 0.1 0.33 11.0 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Beta-Casp PF10996.8 RLN60950.1 - 3e-08 33.9 0.0 7e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 RLN60950.1 - 3.6e-07 29.8 0.0 6.8e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain dCache_2 PF08269.11 RLN60950.1 - 0.091 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Cache domain AfsA PF03756.13 RLN60950.1 - 0.12 12.4 0.0 0.35 10.9 0.0 1.8 1 0 0 1 1 1 0 A-factor biosynthesis hotdog domain RCC1 PF00415.18 RLN60951.1 - 7.3e-71 234.6 15.6 4.5e-15 56.0 0.6 6.2 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN60951.1 - 1.6e-33 113.7 36.5 1.3e-11 43.9 2.8 6.9 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 RLN60951.1 - 0.004 16.9 0.1 11 5.7 0.1 3.0 3 0 0 3 3 3 2 TUP1-like enhancer of split DUF1921 PF09081.10 RLN60951.1 - 0.018 15.3 1.0 0.21 11.9 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1921) SUKH-3 PF14433.6 RLN60951.1 - 0.021 15.3 0.4 15 6.0 0.0 3.0 2 1 1 3 3 3 0 SUKH-3 immunity protein IQ PF00612.27 RLN60952.1 - 1.1e-10 40.3 19.0 0.00093 18.8 1.3 4.9 4 0 0 4 4 4 4 IQ calmodulin-binding motif DUF2752 PF10825.8 RLN60952.1 - 0.15 12.2 0.9 0.27 11.3 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) Ank_2 PF12796.7 RLN60953.1 - 2.8e-25 88.7 0.1 2.5e-08 34.4 0.0 4.5 2 1 4 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN60953.1 - 1.8e-21 76.2 3.0 1.2e-05 25.7 0.0 7.5 3 1 5 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN60953.1 - 2.7e-20 72.2 0.1 4.1e-05 23.8 0.0 5.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN60953.1 - 2e-15 56.4 4.7 0.0095 16.4 0.0 6.8 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 RLN60953.1 - 2.4e-13 48.9 0.1 0.16 12.6 0.0 6.3 5 0 0 5 5 5 3 Ankyrin repeat PH PF00169.29 RLN60953.1 - 2e-11 44.3 0.4 4.2e-11 43.3 0.4 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN60953.1 - 2.3e-05 24.7 0.9 9.2e-05 22.8 0.6 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 RLN60953.1 - 0.00025 21.3 0.3 0.00079 19.7 0.2 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain VPS9 PF02204.18 RLN60953.1 - 0.085 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 9 (VPS9) domain PDZ PF00595.24 RLN60953.1 - 0.14 12.5 0.1 0.43 11.0 0.1 1.8 1 0 0 1 1 1 0 PDZ domain DUF4602 PF15375.6 RLN60954.1 - 1.7e-13 51.1 12.1 2.2e-12 47.4 12.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) NOA36 PF06524.12 RLN60955.1 - 4.8 6.4 6.8 16 4.7 6.8 1.8 1 0 0 1 1 1 0 NOA36 protein SR-25 PF10500.9 RLN60956.1 - 8.2 6.0 23.9 0.32 10.6 8.6 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein HSF_DNA-bind PF00447.17 RLN60957.1 - 3.4e-21 75.6 3.1 4.9e-21 75.2 3.1 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding IMUP PF15761.5 RLN60957.1 - 0.045 14.5 13.2 0.42 11.3 3.1 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF4808 PF16066.5 RLN60957.1 - 4.1 8.0 5.7 1.6 9.3 2.3 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4808) Ank PF00023.30 RLN60958.1 - 7.3e-19 67.3 1.7 2.3e-08 34.1 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 RLN60958.1 - 1.4e-16 60.8 0.0 2e-08 34.7 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN60958.1 - 7.3e-16 58.0 0.7 2.1e-09 37.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN60958.1 - 2.2e-15 56.8 1.3 1.8e-06 28.4 0.0 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN60958.1 - 2.5e-13 48.9 0.4 1.8e-06 27.8 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat DUF4231 PF14015.6 RLN60958.1 - 0.56 10.7 5.7 0.11 13.0 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Nop PF01798.18 RLN60959.1 - 2e-67 227.1 0.0 3.4e-67 226.3 0.0 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 RLN60959.1 - 5.6e-36 124.1 3.8 5.6e-36 124.1 3.8 1.8 2 0 0 2 2 2 1 Prp31 C terminal domain DEAD PF00270.29 RLN60960.1 - 2.2e-45 154.6 0.0 5e-45 153.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN60960.1 - 5e-17 62.2 0.0 3.1e-16 59.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN60960.1 - 8.8e-08 32.3 0.0 2.4e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 RLN60960.1 - 0.0012 18.2 0.0 0.0018 17.6 0.0 1.5 1 1 0 1 1 1 1 SecA DEAD-like domain DUF4217 PF13959.6 RLN60960.1 - 0.013 15.7 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) AAA_22 PF13401.6 RLN60960.1 - 0.17 12.2 0.1 3.4 7.9 0.0 2.8 2 1 1 3 3 3 0 AAA domain 2OG-FeII_Oxy PF03171.20 RLN60961.1 - 3e-06 27.7 0.0 9.7e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DEAD PF00270.29 RLN60962.1 - 1.2e-45 155.5 0.1 3.2e-44 150.8 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN60962.1 - 7e-18 65.0 0.0 1e-16 61.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN60962.1 - 5.3e-08 33.1 0.0 1.7e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4217 PF13959.6 RLN60962.1 - 0.1 12.8 0.1 0.71 10.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4217) AAA_22 PF13401.6 RLN60962.1 - 0.12 12.7 0.3 0.41 10.9 0.3 1.9 1 1 0 1 1 1 0 AAA domain Peptidase_C69 PF03577.15 RLN60963.1 - 4.4e-56 190.5 0.0 1.2e-55 189.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase family C69 DUF1045 PF06299.12 RLN60964.1 - 0.11 12.5 0.7 0.57 10.1 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1045) EMP24_GP25L PF01105.24 RLN60965.1 - 3.8e-13 49.8 2.6 2.1e-08 34.3 0.8 2.2 1 1 1 2 2 2 2 emp24/gp25L/p24 family/GOLD Claudin_2 PF13903.6 RLN60965.1 - 0.038 13.7 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Ank PF00023.30 RLN60967.1 - 2.9e-10 40.1 2.5 7.5e-10 38.8 0.3 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 RLN60967.1 - 6.6e-10 39.3 0.2 1.1e-07 32.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN60967.1 - 3.6e-09 36.7 0.4 3.1e-08 33.7 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN60967.1 - 7.7e-09 35.1 1.0 9.9e-06 25.5 0.1 3.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 RLN60967.1 - 2.6e-08 34.3 0.0 3.6e-06 27.5 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ion_trans PF00520.31 RLN60967.1 - 0.0011 18.3 3.7 0.0017 17.6 3.7 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 RLN60967.1 - 0.02 13.6 1.6 0.025 13.3 0.8 1.4 1 1 0 1 1 1 0 Polycystin cation channel Ank_2 PF12796.7 RLN60968.1 - 2.7e-10 40.7 0.0 2.4e-06 28.0 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN60968.1 - 2.3e-06 27.8 0.3 0.62 10.4 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN60968.1 - 6.6e-05 23.2 0.0 3.9 8.1 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 RLN60968.1 - 0.0003 21.0 0.1 0.61 10.8 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat 2OG-FeII_Oxy_3 PF13640.6 RLN60968.1 - 0.0031 18.3 0.1 0.013 16.3 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Ank_4 PF13637.6 RLN60968.1 - 0.011 16.3 0.0 1.6 9.4 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) HrpJ PF07201.11 RLN60968.1 - 0.067 13.5 0.7 0.12 12.6 0.7 1.4 1 0 0 1 1 1 0 HrpJ-like domain Endonuc-BglII PF09195.11 RLN60968.1 - 0.072 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease BglII Ank_4 PF13637.6 RLN60991.1 - 0.08 13.6 0.3 0.34 11.5 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) FYVE PF01363.21 RLN60992.1 - 4.1e-13 49.3 4.6 7.8e-13 48.4 4.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN60992.1 - 0.03 14.6 5.0 0.029 14.6 1.7 2.4 3 0 0 3 3 3 0 FYVE-type zinc finger DUF1677 PF07911.13 RLN60992.1 - 0.079 13.4 0.3 0.33 11.4 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1677) GIDA PF01134.22 RLN60993.1 - 8.2e-149 496.0 0.0 1.2e-148 495.4 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 RLN60993.1 - 2e-60 204.6 0.2 2.9e-60 204.1 0.2 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 RLN60993.1 - 3.3e-08 33.3 1.1 3.3e-08 33.3 1.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 RLN60993.1 - 4.6e-07 29.3 3.8 1e-05 24.8 3.3 2.4 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 RLN60993.1 - 1.4e-06 27.8 3.6 6.4e-06 25.6 3.6 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RLN60993.1 - 0.00018 21.2 3.1 0.2 11.2 1.3 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 RLN60993.1 - 0.00065 20.2 0.9 0.0016 19.0 0.9 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 RLN60993.1 - 0.0007 19.0 0.8 0.0023 17.2 0.4 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 RLN60993.1 - 0.001 18.4 0.2 0.06 12.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RLN60993.1 - 0.0034 16.5 1.8 0.25 10.4 1.2 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.17 RLN60993.1 - 0.0068 15.7 0.4 0.032 13.5 0.4 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 RLN60993.1 - 0.014 14.1 5.3 0.048 12.4 1.5 2.8 3 0 0 3 3 3 0 HI0933-like protein Trp_halogenase PF04820.14 RLN60993.1 - 0.15 10.9 1.9 0.77 8.5 1.3 2.0 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.6 RLN60993.1 - 0.18 12.3 0.4 0.5 10.8 0.4 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 RLN60993.1 - 0.21 11.8 1.7 0.64 10.3 1.7 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_6 PF08030.12 RLN61061.1 - 2.5e-33 115.4 0.0 1.5e-31 109.6 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 RLN61061.1 - 4.8e-19 68.5 0.0 1e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 RLN61061.1 - 1.2e-14 54.5 9.0 1.2e-14 54.5 9.0 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 RLN61061.1 - 0.00039 21.0 0.0 0.0097 16.5 0.0 2.4 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain EF-hand_7 PF13499.6 RLN61061.1 - 0.018 15.5 0.9 0.04 14.4 0.9 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 RLN61061.1 - 0.079 12.9 0.1 0.23 11.5 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain DUF35_N PF12172.8 RLN61061.1 - 1.2 9.1 4.2 3.1 7.7 4.2 1.7 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) IQ PF00612.27 RLN61062.1 - 0.053 13.3 9.7 1.4 8.9 1.2 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif LXG PF04740.12 RLN61062.1 - 0.078 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily MetJ PF01340.20 RLN61062.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Met Apo-repressor, MetJ IQCJ-SCHIP1 PF15157.6 RLN61062.1 - 0.25 11.2 1.9 0.25 11.2 0.1 1.9 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Ribosomal_S17 PF00366.20 RLN61063.1 - 4.1e-27 94.1 0.9 4.1e-27 94.1 0.9 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 eIF-1a PF01176.19 RLN61063.1 - 0.054 13.3 0.6 1.1 9.1 0.0 2.4 1 1 0 2 2 2 0 Translation initiation factor 1A / IF-1 MORN PF02493.20 RLN61064.1 - 2.5e-08 33.3 34.5 0.089 12.7 0.3 8.7 8 1 0 8 8 8 7 MORN repeat Arm PF00514.23 RLN61065.1 - 3.1e-31 106.4 6.7 0.00035 20.5 0.1 7.6 7 0 0 7 7 7 6 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 RLN61065.1 - 3.1e-07 30.3 1.5 0.23 11.5 0.0 4.5 4 1 1 5 5 5 2 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 RLN61065.1 - 4.8e-06 26.4 12.2 0.31 11.4 0.0 7.8 8 1 1 9 9 9 1 HEAT repeat HEAT_PBS PF03130.16 RLN61065.1 - 1.9e-05 24.9 17.2 5.6 7.9 0.1 7.0 7 0 0 7 7 7 3 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 RLN61065.1 - 2.1e-05 24.9 10.0 1 9.9 0.1 6.1 4 3 1 5 5 5 4 HEAT-like repeat DUF4800 PF16057.5 RLN61065.1 - 0.01 15.1 0.0 0.63 9.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4800) Arm_2 PF04826.13 RLN61065.1 - 0.02 14.4 0.0 1.5 8.3 0.0 2.4 1 1 1 2 2 2 0 Armadillo-like Pro_isomerase PF00160.21 RLN61066.1 - 7.1e-37 127.1 0.0 1.7e-36 125.9 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arm PF00514.23 RLN61066.1 - 8.9e-08 31.9 0.0 0.023 14.7 0.0 3.5 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HD-ZIP_N PF04618.12 RLN61066.1 - 0.02 15.4 0.6 4.1 8.0 0.8 2.9 2 0 0 2 2 2 0 HD-ZIP protein N terminus HEAT PF02985.22 RLN61066.1 - 0.054 13.8 0.0 0.65 10.4 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat Spore_II_R PF09551.10 RLN61066.1 - 1.9 9.0 9.3 2 8.9 0.5 3.0 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) Exo_endo_phos PF03372.23 RLN61067.1 - 1.6e-07 31.1 0.1 8.5e-07 28.7 0.1 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Dymeclin PF09742.9 RLN61068.1 - 2.4e-123 412.8 2.4 3e-123 412.5 2.4 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein TetR_C_15 PF17918.1 RLN61068.1 - 3.9 8.3 8.1 3.8 8.3 0.1 4.4 3 1 1 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Spermine_synth PF01564.17 RLN61069.1 - 1.5e-65 220.1 0.1 2.6e-65 219.4 0.0 1.4 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 RLN61069.1 - 6.3e-21 74.0 0.2 1.3e-20 73.0 0.2 1.6 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 RLN61069.1 - 0.00029 21.5 0.1 0.00088 19.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 RLN61069.1 - 0.0049 17.9 0.0 0.013 16.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.11 RLN61069.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.6 RLN61069.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain zf-U1 PF06220.12 RLN61070.1 - 0.00016 21.4 0.5 0.00024 20.8 0.5 1.3 1 0 0 1 1 1 1 U1 zinc finger TraT PF05818.12 RLN61071.1 - 0.041 13.6 0.9 0.079 12.6 0.9 1.5 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Keratin_2_head PF16208.5 RLN61071.1 - 0.54 10.4 20.1 0.89 9.7 20.1 1.3 1 0 0 1 1 1 0 Keratin type II head Ank_4 PF13637.6 RLN61072.1 - 8e-17 61.4 2.0 2.9e-09 37.3 0.0 4.1 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN61072.1 - 6.8e-15 54.8 4.2 2.1e-06 27.9 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 RLN61072.1 - 7.5e-14 52.1 2.4 3.3e-07 30.8 0.1 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN61072.1 - 1.2e-11 43.7 4.8 0.0022 18.3 0.0 5.5 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 RLN61072.1 - 1.9e-06 28.1 7.1 0.0049 17.1 0.4 4.0 3 2 1 4 4 4 3 Ankyrin repeats (many copies) DUF3807 PF12720.7 RLN61072.1 - 2.2 8.5 9.5 3.7 7.8 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) LPD25 PF18840.1 RLN61073.1 - 0.054 14.0 1.4 0.16 12.5 1.4 1.9 1 0 0 1 1 1 0 Large polyvalent protein associated domain 25 ParB_C PF18064.1 RLN61073.1 - 0.21 11.8 2.1 2.5 8.4 0.1 2.6 2 0 0 2 2 2 0 Centromere-binding protein ParB C-terminal HALZ PF02183.18 RLN61073.1 - 0.98 9.7 24.2 0.72 10.1 1.3 4.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.6 RLN61073.1 - 1.8 8.7 15.4 13 6.0 0.6 4.2 3 0 0 3 3 3 0 Sperm tail C-terminal domain Methyltransf_31 PF13847.6 RLN61074.1 - 2.8e-14 53.2 0.0 3.2e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN61074.1 - 1.7e-10 41.5 0.0 5e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 RLN61074.1 - 1.5e-09 37.7 0.0 4.5e-09 36.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 RLN61074.1 - 2.8e-08 33.5 0.0 3.9e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 RLN61074.1 - 4.8e-07 30.3 0.0 1.3e-06 29.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN61074.1 - 3e-06 27.9 0.0 6.7e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN61074.1 - 1e-05 25.4 0.0 2.5e-05 24.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_10 PF05971.12 RLN61074.1 - 4.6e-05 22.9 0.0 6.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase Methyltransf_18 PF12847.7 RLN61074.1 - 0.00026 20.9 0.0 0.00048 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 RLN61074.1 - 0.00064 19.5 0.0 0.0019 18.0 0.0 1.8 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 RLN61074.1 - 0.0086 15.7 0.1 0.061 13.0 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_2 PF00891.18 RLN61074.1 - 0.034 13.4 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 RLN61074.1 - 0.038 13.3 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.10 RLN61074.1 - 0.056 13.0 0.0 0.12 11.9 0.0 1.5 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase CitT PF12431.8 RLN61074.1 - 0.12 12.8 0.1 0.38 11.2 0.1 2.0 1 0 0 1 1 1 0 Transcriptional regulator TrmK PF04816.12 RLN61074.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_9 PF08003.11 RLN61074.1 - 0.16 10.9 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Ribosomal_L32e PF01655.18 RLN61075.1 - 8.1e-49 164.5 1.6 9.9e-49 164.3 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Sugar_tr PF00083.24 RLN61100.1 - 3.3e-100 336.1 23.4 3.7e-100 335.9 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN61100.1 - 1e-28 100.3 34.0 8.6e-21 74.2 9.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 RLN61100.1 - 0.0045 15.3 0.2 0.0045 15.3 0.2 1.7 2 0 0 2 2 2 1 BT1 family DUF3054 PF11255.8 RLN61100.1 - 0.021 15.3 0.2 0.021 15.3 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3054) Sugar_tr PF00083.24 RLN61131.1 - 1.4e-99 334.0 26.2 1.6e-99 333.8 26.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN61131.1 - 3.8e-25 88.6 38.1 1.2e-18 67.2 5.5 2.7 1 1 1 3 3 3 3 Major Facilitator Superfamily DUF1388 PF07142.12 RLN61131.1 - 0.12 12.4 0.5 0.19 11.7 0.5 1.3 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) ABC2_membrane PF01061.24 RLN61132.1 - 3.7e-35 121.3 24.7 3.7e-35 121.3 24.7 1.5 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN61132.1 - 4.1e-23 82.4 0.5 2.7e-20 73.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 RLN61132.1 - 0.0038 16.4 18.2 0.0082 15.3 18.1 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.6 RLN61132.1 - 0.0042 17.5 0.9 0.0079 16.6 0.0 1.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_29 PF13555.6 RLN61132.1 - 0.0048 16.6 2.7 0.06 13.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN61132.1 - 0.005 16.8 0.9 0.32 10.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 RLN61132.1 - 0.013 15.8 1.2 0.053 13.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 RLN61132.1 - 0.015 14.7 0.1 5.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SMC_N PF02463.19 RLN61132.1 - 0.029 13.8 0.1 7.7 5.9 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 RLN61132.1 - 0.043 13.1 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 RLN61132.1 - 0.17 11.5 0.4 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain PDR_assoc PF08370.11 RLN61132.1 - 5.5 6.8 10.3 0.084 12.6 1.3 2.4 2 0 0 2 2 2 0 Plant PDR ABC transporter associated HMG-CoA_red PF00368.18 RLN61146.1 - 2.4e-52 178.2 0.2 3.7e-52 177.5 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HTH_57 PF18679.1 RLN61146.1 - 0.079 13.3 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 ThcOx helix turn helix domain HECT PF00632.25 RLN61147.1 - 1e-06 28.5 0.0 2.3e-06 27.3 0.0 1.5 1 1 0 2 2 2 1 HECT-domain (ubiquitin-transferase) MatE PF01554.18 RLN61282.1 - 9.5e-38 129.4 35.7 8.8e-19 67.7 13.4 2.2 2 0 0 2 2 2 2 MatE His_biosynth PF00977.21 RLN61283.1 - 0.065 12.7 0.1 0.12 11.8 0.1 1.4 1 1 0 1 1 1 0 Histidine biosynthesis protein Tub PF01167.18 RLN61284.1 - 1.5e-58 198.4 0.1 2.9e-58 197.5 0.1 1.4 1 0 0 1 1 1 1 Tub family WD40 PF00400.32 RLN61284.1 - 6.4e-11 42.6 3.3 5.7e-05 23.8 0.3 7.4 6 1 1 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN61284.1 - 4e-09 36.7 0.1 0.18 12.1 0.0 5.1 1 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Pkinase_Tyr PF07714.17 RLN61284.1 - 0.055 12.7 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase WD40_like PF17005.5 RLN61284.1 - 0.077 12.3 0.0 3.2 7.0 0.0 2.8 3 0 0 3 3 3 0 WD40-like domain SRA1 PF07304.11 RLN61284.1 - 0.15 11.9 0.0 0.15 11.9 0.0 3.1 4 0 0 4 4 4 0 Steroid receptor RNA activator (SRA1) TPR_1 PF00515.28 RLN61284.1 - 0.32 10.9 1.7 24 5.0 0.5 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN61284.1 - 0.52 10.6 9.6 2.1 8.7 0.5 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3527 PF12043.8 RLN61284.1 - 0.82 9.2 4.2 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) MatE PF01554.18 RLN61285.1 - 7.3e-24 84.2 19.4 4e-19 68.9 13.2 2.2 2 0 0 2 2 2 2 MatE OST3_OST6 PF04756.13 RLN61285.1 - 0.17 11.2 2.9 0.24 10.7 0.8 2.0 1 1 1 2 2 2 0 OST3 / OST6 family, transporter family MTP18 PF10558.9 RLN61286.1 - 0.15 12.0 0.7 0.25 11.3 0.7 1.3 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) Trypan_glycop PF00913.19 RLN61286.1 - 4.3 6.5 4.8 6.1 6.0 4.8 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) Kelch_1 PF01344.25 RLN61287.1 - 2.1e-62 206.4 0.1 1.3e-15 56.7 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RLN61287.1 - 3.5e-44 147.7 0.0 2.2e-09 37.3 0.0 6.3 4 1 2 6 6 6 5 Kelch motif Kelch_4 PF13418.6 RLN61287.1 - 2e-33 114.2 0.0 1.3e-05 25.1 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 RLN61287.1 - 6.9e-26 89.2 0.4 0.00023 21.0 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 RLN61287.1 - 2.9e-23 81.6 0.9 1.7e-06 28.2 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain BTB PF00651.31 RLN61287.1 - 5.6e-22 78.1 0.0 1.4e-21 76.8 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.6 RLN61287.1 - 1e-11 44.5 2.0 0.097 12.7 0.0 6.4 6 0 0 6 6 6 3 Kelch motif BACK PF07707.15 RLN61287.1 - 9.6e-06 25.6 0.1 2.9e-05 24.1 0.1 1.8 1 1 0 1 1 1 1 BTB And C-terminal Kelch Choline_transpo PF04515.12 RLN61288.1 - 2.2e-71 240.7 25.0 2.2e-71 240.7 25.0 2.2 2 1 0 2 2 2 1 Plasma-membrane choline transporter Mucin PF01456.17 RLN61317.1 - 0.037 14.0 2.7 0.056 13.4 2.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF4407 PF14362.6 RLN61317.1 - 0.19 11.1 1.3 0.77 9.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AA_permease PF00324.21 RLN61318.1 - 9.1e-49 166.3 19.9 1.1e-48 166.0 19.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 RLN61318.1 - 1.9e-18 66.6 25.8 2.8e-18 66.0 25.8 1.3 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 RLN61318.1 - 3.8e-15 55.9 1.5 2.3e-09 36.8 0.1 3.0 1 1 2 3 3 3 3 Solute carrier family 12 SMP_2 PF10144.9 RLN61318.1 - 0.3 10.7 4.0 1.8 8.2 0.1 2.5 2 0 0 2 2 2 0 Bacterial virulence factor haemolysin Pkinase PF00069.25 RLN61319.1 - 1.2e-53 182.2 0.0 1.4e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN61319.1 - 2.3e-26 92.7 0.0 2.7e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN61319.1 - 3.5e-08 33.1 0.0 4.4e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN61319.1 - 1.9e-07 30.7 0.0 2.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN61319.1 - 2.4e-06 26.6 0.0 2.8e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN61319.1 - 0.00026 21.0 0.0 0.00032 20.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 RLN61319.1 - 0.051 13.2 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 RLN61319.1 - 0.088 12.4 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 RLN61319.1 - 0.093 12.2 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL AAA_11 PF13086.6 RLN61321.1 - 5.8e-27 95.1 0.0 5.8e-27 95.1 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_30 PF13604.6 RLN61321.1 - 3.8e-08 33.3 0.2 1.1e-07 31.8 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RLN61321.1 - 6e-05 23.3 0.0 0.00023 21.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RLN61321.1 - 8.7e-05 22.9 0.2 0.00021 21.6 0.2 1.7 1 1 0 1 1 1 1 AAA domain YL1 PF05764.13 RLN61321.1 - 0.00068 19.8 16.7 0.00068 19.8 16.7 2.5 2 1 0 2 2 1 1 YL1 nuclear protein T2SSE PF00437.20 RLN61321.1 - 0.00074 18.7 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 RLN61321.1 - 0.0033 17.8 0.0 0.0079 16.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN61321.1 - 0.0044 17.4 0.1 0.022 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 RLN61321.1 - 0.04 13.8 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain DUF3787 PF12655.7 RLN61321.1 - 0.064 13.2 0.3 0.15 12.1 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3787) AAA_33 PF13671.6 RLN61321.1 - 0.071 13.3 0.3 0.29 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RLN61321.1 - 0.072 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 RLN61321.1 - 0.094 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Mg_chelatase PF01078.21 RLN61321.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 RLN61321.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RLN61321.1 - 0.12 12.9 0.5 0.32 11.5 0.0 2.0 2 0 0 2 2 1 0 AAA domain Viral_helicase1 PF01443.18 RLN61321.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 RLN61321.1 - 0.15 11.8 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN61321.1 - 1.2 9.6 4.0 0.63 10.5 0.2 2.1 2 0 0 2 2 2 0 AAA domain TrmO PF01980.16 RLN61322.1 - 1.4e-19 70.5 0.1 2.7e-10 40.5 0.0 2.5 1 1 1 2 2 2 2 tRNA-methyltransferase O YcgR PF07317.12 RLN61322.1 - 0.016 15.1 0.3 0.034 14.0 0.3 1.5 1 0 0 1 1 1 0 Flagellar regulator YcgR TrmO_C PF18389.1 RLN61322.1 - 0.042 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 TrmO C-terminal domain TPR_10 PF13374.6 RLN61322.1 - 0.21 11.5 4.7 0.21 11.5 1.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_transf_24 PF18404.1 RLN61323.1 - 1.5e-137 457.4 2.0 2.4e-137 456.7 2.0 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 RLN61323.1 - 4.5e-32 112.0 0.3 1.4e-26 94.0 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like domain UDP-g_GGTase PF06427.11 RLN61323.1 - 1.5e-23 83.0 0.0 3.9e-23 81.6 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 RLN61323.1 - 7.5e-23 80.9 3.5 1e-22 80.5 1.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 RLN61323.1 - 1.1e-17 64.5 0.0 2.6e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 RLN61323.1 - 1.3e-05 24.9 0.1 2.8e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Thioredoxin_15 PF18403.1 RLN61323.1 - 3.1e-05 24.0 2.5 0.15 12.0 0.0 3.8 3 0 0 3 3 3 2 Thioredoxin-like domain RelB_leu_zip PF16180.5 RLN61323.1 - 0.13 12.2 0.0 0.4 10.7 0.0 1.8 1 0 0 1 1 1 0 RelB leucine zipper RRM_1 PF00076.22 RLN61324.1 - 1.1e-21 76.4 0.1 1.7e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 RLN61324.1 - 6.5e-16 58.8 4.0 6.5e-16 58.8 4.0 2.2 2 1 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal AAA_12 PF13087.6 RLN61325.1 - 2.3e-49 167.7 0.0 3.5e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain VPS13 PF16908.5 RLN61326.1 - 6.9e-05 22.7 1.6 0.26 11.0 0.0 2.7 2 0 0 2 2 2 2 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 RLN61326.1 - 0.021 14.9 0.0 0.082 13.0 0.0 2.1 1 0 0 1 1 1 0 N-terminal region of Chorein or VPS13 DUF2457 PF10446.9 RLN61326.1 - 0.88 8.6 5.4 1.5 7.9 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Clat_adaptor_s PF01217.20 RLN61327.1 - 4.4e-26 91.5 2.9 1.1e-18 67.5 0.6 2.4 1 1 1 2 2 2 2 Clathrin adaptor complex small chain Dimer_Tnp_hAT PF05699.14 RLN61327.1 - 2.7e-11 43.1 0.0 1.2e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 RLN61327.1 - 0.00021 21.2 1.5 0.00038 20.4 0.2 2.2 2 0 0 2 2 2 1 BED zinc finger zf-C2H2_4 PF13894.6 RLN61327.1 - 0.048 14.5 1.5 0.22 12.4 1.5 2.3 1 0 0 1 1 1 0 C2H2-type zinc finger DUF4413 PF14372.6 RLN61327.1 - 0.11 12.9 0.0 0.33 11.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Thiolase_N PF00108.23 RLN61328.1 - 2e-82 276.5 0.3 3.5e-81 272.4 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RLN61328.1 - 2e-48 163.1 0.9 5.5e-48 161.7 0.2 2.2 4 0 0 4 4 4 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 RLN61328.1 - 0.00048 19.8 6.2 0.095 12.3 0.2 4.1 3 1 1 4 4 4 3 Beta-ketoacyl synthase, N-terminal domain RF-1 PF00472.20 RLN61342.1 - 1.1e-06 28.5 1.2 1.1e-06 28.5 1.2 2.0 2 0 0 2 2 2 1 RF-1 domain Myc_N PF01056.18 RLN61342.1 - 0.0046 16.9 9.5 0.0051 16.8 9.5 1.2 1 0 0 1 1 1 1 Myc amino-terminal region RNA_pol_3_Rpc31 PF11705.8 RLN61342.1 - 0.05 13.9 25.5 0.063 13.5 25.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 RLN61342.1 - 0.064 12.6 23.4 0.084 12.2 23.4 1.1 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.10 RLN61342.1 - 0.15 11.3 20.2 0.17 11.2 20.2 1.2 1 0 0 1 1 1 0 BUD22 DUF4834 PF16118.5 RLN61342.1 - 0.16 12.9 9.2 0.19 12.7 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Cwf_Cwc_15 PF04889.12 RLN61342.1 - 0.31 10.7 25.0 0.36 10.5 25.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DASH_Spc19 PF08287.11 RLN61342.1 - 0.33 10.8 10.4 0.5 10.2 10.4 1.3 1 0 0 1 1 1 0 Spc19 MIF4G_like_2 PF09090.11 RLN61342.1 - 0.39 10.2 5.4 0.49 9.8 5.4 1.2 1 0 0 1 1 1 0 MIF4G like PPP4R2 PF09184.11 RLN61342.1 - 0.48 10.0 17.4 0.51 9.9 17.4 1.1 1 0 0 1 1 1 0 PPP4R2 CNDH2_C PF16858.5 RLN61342.1 - 0.62 9.9 13.4 0.72 9.7 13.4 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term IFT57 PF10498.9 RLN61342.1 - 0.67 8.9 11.9 0.79 8.6 11.9 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Pns11_12 PF17464.2 RLN61342.1 - 1 9.1 12.0 1.1 8.9 12.0 1.1 1 0 0 1 1 1 0 Non-structural protein 11 and 12 Nop14 PF04147.12 RLN61342.1 - 1.1 7.4 25.5 1.2 7.3 25.5 1.1 1 0 0 1 1 1 0 Nop14-like family FAM60A PF15396.6 RLN61342.1 - 2.3 8.2 6.5 2.6 8.0 6.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A TFIIA PF03153.13 RLN61342.1 - 2.9 7.8 22.1 3.4 7.6 22.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF913 PF06025.12 RLN61342.1 - 3 6.7 6.1 3.2 6.6 6.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4746 PF15928.5 RLN61342.1 - 3.4 7.0 12.1 4.2 6.7 12.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Astro_capsid_p PF12226.8 RLN61342.1 - 3.7 6.6 21.4 4.6 6.3 21.4 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF3295 PF11702.8 RLN61342.1 - 6 6.1 16.2 6.8 5.9 16.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) RPN2_C PF18004.1 RLN61342.1 - 6.7 6.6 15.2 8.5 6.3 15.2 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain NPR3 PF03666.13 RLN61342.1 - 9.3 4.9 14.1 10 4.8 14.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PAXNEB PF05625.11 RLN61343.1 - 7.1e-71 239.3 0.0 8.2e-71 239.1 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein LpxK PF02606.14 RLN61344.1 - 2.3e-54 184.7 0.1 3.6e-54 184.1 0.1 1.3 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase AsnA PF03590.15 RLN61344.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Aspartate-ammonia ligase Thioredoxin PF00085.20 RLN61373.1 - 6.6e-62 205.9 1.9 1.6e-30 105.1 0.0 3.4 3 1 1 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 RLN61373.1 - 2.8e-31 108.9 0.5 1.5e-21 77.1 0.1 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 RLN61373.1 - 2.8e-14 53.5 1.6 0.00015 22.2 0.0 4.3 3 2 0 3 3 3 3 Thioredoxin-like domain CybS PF05328.12 RLN61373.1 - 2.7e-12 46.5 0.0 5.7e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Thioredoxin_7 PF13899.6 RLN61373.1 - 3.6e-09 36.7 0.0 0.0049 17.0 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 RLN61373.1 - 6.2e-07 29.4 0.8 0.015 15.2 0.0 3.1 3 0 0 3 3 3 2 AhpC/TSA family OST3_OST6 PF04756.13 RLN61373.1 - 1.2e-06 28.1 0.3 0.057 12.8 0.0 2.9 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 RLN61373.1 - 4.1e-06 27.0 0.0 0.033 14.5 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like Redoxin PF08534.10 RLN61373.1 - 0.00056 19.6 0.7 0.89 9.3 0.0 3.5 3 0 0 3 3 3 2 Redoxin EF-hand_6 PF13405.6 RLN61373.1 - 0.011 15.6 0.0 4.3 7.5 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 RLN61373.1 - 0.028 14.0 0.2 6.5 6.6 0.0 2.9 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 RLN61373.1 - 0.048 14.1 0.1 24 5.5 0.0 3.0 2 0 0 2 2 2 0 EF-hand domain pair US30 PF17624.2 RLN61374.1 - 0.044 12.8 0.1 0.057 12.5 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function RCC1 PF00415.18 RLN61375.1 - 1e-51 173.3 20.4 4e-11 43.4 0.1 7.2 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN61375.1 - 7.8e-21 73.3 30.7 0.00012 21.7 2.5 7.5 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Phyto-Amp PF15438.6 RLN61375.1 - 0.42 10.4 2.2 2.3 8.0 0.0 2.7 3 0 0 3 3 3 0 Antigenic membrane protein of phytoplasma PKcGMP_CC PF16808.5 RLN61375.1 - 8 6.4 10.0 4.2 7.3 0.2 5.0 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase LPMO_10 PF03067.15 RLN61377.1 - 4.1e-07 30.9 0.0 5.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 RLN61377.1 - 0.027 14.4 0.1 0.08 12.9 0.1 1.8 1 1 1 2 2 2 0 Glycosyl hydrolase family 61 zf-MYND PF01753.18 RLN61378.1 - 0.45 10.6 5.0 7.2 6.8 0.1 2.8 2 0 0 2 2 2 0 MYND finger Fz PF01392.22 RLN61378.1 - 0.71 10.5 9.0 0.82 10.3 7.2 2.0 1 1 0 1 1 1 0 Fz domain Peptidase_C69 PF03577.15 RLN61379.1 - 8e-55 186.4 0.0 2.6e-54 184.7 0.0 1.8 1 1 0 1 1 1 1 Peptidase family C69 Wtap PF17098.5 RLN61402.1 - 0.00068 19.6 8.1 0.1 12.5 0.7 2.4 2 0 0 2 2 2 2 WTAP/Mum2p family DUF5401 PF17380.2 RLN61402.1 - 1.4 6.9 23.4 1.8 6.5 23.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) BRE1 PF08647.11 RLN61402.1 - 2 8.6 18.6 2.7 8.1 10.8 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Ephrin_rec_like PF07699.13 RLN61404.1 - 3e-09 36.5 20.3 1.8e-06 27.6 2.9 3.1 2 1 1 3 3 3 2 Putative ephrin-receptor like NCD3G PF07562.14 RLN61404.1 - 0.0012 18.8 10.0 0.01 15.8 0.5 2.7 3 0 0 3 3 3 2 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 RLN61404.1 - 0.079 13.4 6.5 0.45 11.0 2.7 3.0 2 2 0 2 2 2 0 TNFR/NGFR cysteine-rich region TPX2 PF06886.11 RLN61405.1 - 3.9e-11 43.0 19.0 3.9e-11 43.0 19.0 7.7 9 0 0 9 9 9 3 Targeting protein for Xklp2 (TPX2) TPX2_importin PF12214.8 RLN61405.1 - 0.00012 22.3 74.1 0.00098 19.4 19.1 7.5 4 2 3 7 7 7 2 Cell cycle regulated microtubule associated protein GTP_EFTU PF00009.27 RLN61406.1 - 8e-64 214.8 0.0 1.4e-63 214.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 RLN61406.1 - 1.9e-27 95.1 0.0 4.6e-27 93.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 RLN61406.1 - 1.4e-20 73.2 0.0 3.3e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 RLN61406.1 - 4.2e-10 39.5 0.0 1.1e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 RLN61406.1 - 9.3e-08 32.4 0.1 2.9e-07 30.8 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 RLN61406.1 - 1.9e-07 30.9 0.0 4.2e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 RLN61406.1 - 0.018 15.1 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Pyrophosphatase PF00719.19 RLN61407.1 - 8.4e-47 159.0 0.0 1.1e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase PLAC8 PF04749.17 RLN61408.1 - 9.2e-18 65.1 11.6 2.8e-17 63.5 11.6 1.7 1 1 0 1 1 1 1 PLAC8 family WD40 PF00400.32 RLN61409.1 - 3.3e-30 103.7 23.4 3.2e-05 24.6 0.3 10.0 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN61409.1 - 5.1e-13 49.1 0.0 0.0011 19.3 0.0 6.3 5 2 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 RLN61409.1 - 0.0027 17.4 5.1 0.22 11.1 0.1 3.4 3 0 0 3 3 3 1 PQQ-like domain Ge1_WD40 PF16529.5 RLN61409.1 - 0.0027 16.7 0.0 2.2 7.2 0.0 3.2 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein RAB3GAP2_N PF14655.6 RLN61409.1 - 0.013 14.8 0.0 0.1 11.8 0.0 2.4 2 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.8 RLN61409.1 - 0.014 14.1 0.9 0.19 10.3 0.2 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 SGL PF08450.12 RLN61409.1 - 0.014 15.0 0.0 0.27 10.8 0.0 2.8 3 1 1 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region Cytochrom_D1 PF02239.16 RLN61409.1 - 0.096 11.2 0.0 0.48 8.9 0.0 2.2 3 0 0 3 3 3 0 Cytochrome D1 heme domain Hira PF07569.11 RLN61409.1 - 0.11 12.1 2.7 6.8 6.3 0.0 3.8 4 1 1 5 5 5 0 TUP1-like enhancer of split RINGv PF12906.7 RLN61410.1 - 2.7e-11 43.4 4.2 5.3e-11 42.5 4.2 1.5 1 0 0 1 1 1 1 RING-variant domain FHA PF00498.26 RLN61410.1 - 2.6e-08 34.1 0.0 8.1e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 RLN61410.1 - 0.00098 19.4 0.0 0.0024 18.2 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_2 PF13639.6 RLN61410.1 - 2.3 8.6 5.4 13 6.2 5.9 2.0 1 1 1 2 2 2 0 Ring finger domain Peptidase_S66 PF02016.15 RLN61411.1 - 6.1e-34 116.7 0.1 2.3e-33 114.8 0.1 1.9 1 1 0 1 1 1 1 LD-carboxypeptidase N-terminal domain Peptidase_S66C PF17676.1 RLN61411.1 - 1.7e-24 86.7 0.0 2.7e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase C-terminal domain NBD_C PF17042.5 RLN61411.1 - 0.003 18.1 0.2 0.005 17.4 0.2 1.3 1 0 0 1 1 1 1 Nucleotide-binding C-terminal domain ALGX PF16822.5 RLN61411.1 - 0.063 13.0 0.3 0.11 12.1 0.3 1.4 1 0 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX p450 PF00067.22 RLN61412.1 - 8.7e-15 54.4 0.0 1e-14 54.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Baculo_LEF-2 PF03041.14 RLN61412.1 - 0.097 12.3 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 lef-2 WD40 PF00400.32 RLN61459.1 - 6e-24 83.9 16.4 2.1e-05 25.2 0.3 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 RLN61459.1 - 1.2e-07 31.0 2.1 0.0047 15.9 0.1 3.6 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 RLN61459.1 - 1.1e-05 25.7 0.4 2.2 8.6 0.0 4.9 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain HSF_DNA-bind PF00447.17 RLN61460.1 - 3.3e-20 72.5 2.7 4.6e-20 72.0 2.7 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Mannosyl_trans3 PF11051.8 RLN61461.1 - 1.7e-31 109.6 0.0 6.6e-31 107.7 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative AA_permease_2 PF13520.6 RLN61461.1 - 3.9e-27 95.1 24.7 5.8e-27 94.6 24.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN61461.1 - 3.4e-14 52.3 21.1 2.6e-13 49.4 21.0 2.0 1 1 0 1 1 1 1 Amino acid permease Popeye PF04831.13 RLN61461.1 - 0.36 11.0 1.5 1 9.5 1.5 1.8 1 0 0 1 1 1 0 Popeye protein conserved region Aminotran_3 PF00202.21 RLN61462.1 - 9.3e-107 357.2 0.0 1.2e-103 346.9 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-III Aminotran_1_2 PF00155.21 RLN61462.1 - 3.5e-06 26.5 0.0 4.6e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 RLN61462.1 - 0.003 16.6 0.0 0.0044 16.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 RLN61462.1 - 0.05 12.9 0.0 0.2 10.9 0.0 1.9 1 1 0 1 1 1 0 Beta-eliminating lyase HP1451_C PF18472.1 RLN61462.1 - 0.16 12.0 0.0 0.66 10.0 0.0 1.9 2 0 0 2 2 2 0 HP1451 C-terminal domain Macro PF01661.21 RLN61463.1 - 3.7e-15 56.0 0.0 5.5e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Macro domain aGPT-Pplase2 PF18724.1 RLN61463.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 2 Mannosyl_trans3 PF11051.8 RLN61464.1 - 3e-35 121.9 0.1 3e-33 115.4 0.1 2.3 1 1 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.8 RLN61465.1 - 7.2e-36 124.0 0.0 4.8e-24 85.2 0.0 2.3 1 1 0 2 2 2 2 Mannosyltransferase putative preSET_CXC PF18264.1 RLN61465.1 - 0.36 11.4 0.9 0.73 10.4 0.1 1.8 2 0 0 2 2 2 0 CXC domain LCM PF04072.14 RLN61550.1 - 3.3e-37 128.2 0.0 5.6e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase SAM_MT PF04445.13 RLN61550.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Ammonium_transp PF00909.21 RLN61623.1 - 2.1e-64 217.7 24.0 2.6e-64 217.4 24.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pyr_redox_2 PF07992.14 RLN61623.1 - 0.072 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Alpha-amylase PF00128.24 RLN61624.1 - 1e-11 45.0 0.0 3e-11 43.5 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CBM_25 PF03423.13 RLN61625.1 - 1.1e-12 48.1 6.1 1.1e-12 48.1 6.1 1.7 1 1 0 1 1 1 1 Carbohydrate binding domain (family 25) CBM53 PF16760.5 RLN61625.1 - 1.1e-10 42.0 1.4 1.1e-10 42.0 1.4 1.9 2 1 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) CBM26 PF16738.5 RLN61625.1 - 0.0043 17.3 3.2 0.0082 16.4 1.8 2.3 2 1 0 2 2 2 1 Starch-binding module 26 Ammonium_transp PF00909.21 RLN61626.1 - 7.7e-64 215.8 16.4 9.9e-64 215.5 16.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Ammonium_transp PF00909.21 RLN61627.1 - 2.9e-64 217.2 25.1 3.7e-64 216.9 25.1 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Ammonium_transp PF00909.21 RLN61628.1 - 2.2e-65 220.9 21.1 3e-65 220.5 21.1 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family RACo_C_ter PF14574.6 RLN61628.1 - 0.078 12.0 0.7 0.15 11.1 0.7 1.4 1 0 0 1 1 1 0 C-terminal domain of RACo the ASKHA domain Corona_M PF01635.18 RLN61628.1 - 0.11 11.8 3.0 0.067 12.5 0.2 2.0 2 0 0 2 2 2 0 Coronavirus M matrix/glycoprotein DUF3796 PF12676.7 RLN61628.1 - 0.93 9.9 9.7 0.065 13.7 3.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) MULE PF10551.9 RLN61648.1 - 8.9e-12 45.3 0.8 2.1e-11 44.0 0.8 1.6 1 0 0 1 1 1 1 MULE transposase domain SSP160 PF06933.11 RLN61648.1 - 0.057 11.6 10.8 0.09 11.0 10.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SWIM PF04434.17 RLN61648.1 - 0.1 12.3 1.7 0.24 11.1 1.7 1.6 1 0 0 1 1 1 0 SWIM zinc finger PRP8_domainIV PF12134.8 RLN61680.1 - 9e-128 424.7 0.2 1.6e-127 423.8 0.2 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 RLN61680.1 - 8.1e-90 298.9 2.0 2.1e-89 297.5 2.0 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 U5_2-snRNA_bdg PF10597.9 RLN61680.1 - 8.2e-73 242.8 0.0 1.6e-72 241.9 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 RLN61680.1 - 8.5e-47 157.4 0.4 2.1e-46 156.2 0.4 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCN PF08083.11 RLN61680.1 - 3.8e-43 147.7 0.8 6.8e-43 146.9 0.8 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain HSP70 PF00012.20 RLN61694.1 - 5.8e-124 414.5 0.7 6.6e-124 414.3 0.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN61694.1 - 2.6e-08 33.1 0.5 3.9e-08 32.5 0.5 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Mannosyl_trans3 PF11051.8 RLN61722.1 - 1.3e-26 93.6 0.0 2.8e-26 92.5 0.0 1.6 1 1 0 1 1 1 1 Mannosyltransferase putative Sugar_tr PF00083.24 RLN61723.1 - 1.9e-38 132.5 27.7 1.5e-27 96.6 2.9 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RLN61723.1 - 1.6e-24 86.5 43.2 1.6e-20 73.4 30.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 RLN61723.1 - 0.0016 17.0 1.3 0.0028 16.2 1.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) IFT20 PF14931.6 RLN61724.1 - 0.087 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Sugar_tr PF00083.24 RLN61725.1 - 9e-40 136.9 30.4 8.4e-38 130.4 30.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN61725.1 - 8.6e-31 107.1 55.8 3.1e-27 95.4 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 RLN61725.1 - 0.0036 15.8 1.6 0.0036 15.8 1.6 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector Sugar_tr PF00083.24 RLN61726.1 - 4.5e-43 147.8 27.5 1e-28 100.4 5.4 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RLN61726.1 - 2.3e-29 102.4 34.6 4.4e-26 91.6 26.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 RLN61726.1 - 6.2e-05 21.4 1.0 0.0003 19.2 0.6 2.2 3 0 0 3 3 3 1 BT1 family FTR1 PF03239.14 RLN61726.1 - 0.0038 16.4 6.0 0.0094 15.1 6.0 1.6 1 0 0 1 1 1 1 Iron permease FTR1 family MFS_1_like PF12832.7 RLN61726.1 - 0.032 13.1 12.9 0.17 10.7 6.3 2.9 2 1 1 3 3 3 0 MFS_1 like family DUF5353 PF17304.2 RLN61726.1 - 0.35 10.6 6.2 0.63 9.8 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5353) DUF730 PF05325.11 RLN61728.1 - 0.14 12.2 0.3 1.1 9.3 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF730) Transp_Tc5_C PF04236.15 RLN61728.1 - 9 6.7 12.6 5 7.6 0.9 3.4 1 1 1 3 3 3 0 Tc5 transposase C-terminal domain Myb_DNA-binding PF00249.31 RLN61729.1 - 5.6e-12 45.7 0.4 9.7e-12 44.9 0.4 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN61729.1 - 0.00098 19.0 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 RLN61729.1 - 0.025 14.8 0.2 0.05 13.9 0.2 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Sugar_tr PF00083.24 RLN61733.1 - 2.6e-19 69.4 17.7 3.5e-17 62.4 17.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN61733.1 - 1.3e-09 37.4 43.1 7.9e-07 28.3 23.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily E1-E2_ATPase PF00122.20 RLN61734.1 - 2.6e-27 95.5 1.6 2.6e-27 95.5 1.6 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 RLN61734.1 - 1.7e-13 51.4 0.1 9.6e-08 32.6 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 RLN61734.1 - 9.7e-10 38.6 0.0 2.3e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase PF13246.6 RLN61734.1 - 9e-07 28.9 0.0 2.8e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 RLN61734.1 - 0.00029 20.5 0.0 0.00066 19.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF3796 PF12676.7 RLN61734.1 - 0.14 12.6 0.2 0.5 10.8 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) MFS_2 PF13347.6 RLN61800.1 - 0.0015 17.1 9.9 0.0015 17.1 9.9 2.4 1 1 1 2 2 2 1 MFS/sugar transport protein DUF2583 PF10762.9 RLN61800.1 - 2.7 8.4 7.2 0.36 11.3 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2583) Ceramidase PF05875.12 RLN61824.1 - 4.3e-54 183.7 16.1 5.3e-54 183.4 16.1 1.0 1 0 0 1 1 1 1 Ceramidase Mito_carr PF00153.27 RLN61825.1 - 1.2e-39 134.2 5.3 1.9e-17 63.0 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein NEL PF14496.6 RLN61847.1 - 0.061 12.7 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 C-terminal novel E3 ligase, LRR-interacting TMEM138 PF14935.6 RLN61898.1 - 3.7e-11 43.7 6.3 5.2e-11 43.2 6.3 1.2 1 0 0 1 1 1 1 Transmembrane protein 138 DUF4896 PF16237.5 RLN61898.1 - 2.9 7.8 7.7 2.7 7.9 3.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4896) Peptidase_M24 PF00557.24 RLN61899.1 - 1.4e-49 168.7 0.0 1.7e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 RLN61899.1 - 3.2e-08 33.7 3.6 7.5e-08 32.6 3.6 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 RLN61899.1 - 0.083 13.0 1.2 0.21 11.7 1.2 1.8 1 0 0 1 1 1 0 MYND finger XPG_I PF00867.18 RLN61900.1 - 1.3e-20 73.5 0.1 4.1e-20 71.9 0.1 1.9 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 RLN61900.1 - 4.1e-06 27.2 0.0 8.8e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 RLN61900.1 - 0.0042 16.6 0.1 0.012 15.0 0.0 1.8 2 0 0 2 2 2 1 XPG domain containing DNA_alkylation PF08713.11 RLN61900.1 - 0.11 12.1 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 DNA alkylation repair enzyme CHB_HEX PF03173.13 RLN62010.1 - 0.053 13.2 0.1 0.095 12.4 0.1 1.4 1 1 0 1 1 1 0 Putative carbohydrate binding domain CHB_HEX PF03173.13 RLN62011.1 - 0.11 12.2 0.5 0.2 11.3 0.5 1.5 1 1 0 1 1 1 0 Putative carbohydrate binding domain DnaJ PF00226.31 RLN62023.1 - 2.1e-26 91.8 0.8 4.8e-26 90.7 0.8 1.6 1 0 0 1 1 1 1 DnaJ domain LYTB PF02401.18 RLN62023.1 - 0.038 13.2 0.1 6.2 6.0 0.0 2.1 2 0 0 2 2 2 0 LytB protein COG2 PF06148.11 RLN62023.1 - 0.047 13.8 0.5 0.095 12.8 0.5 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Linker_histone PF00538.19 RLN62086.1 - 2.2e-19 69.6 0.1 2.2e-19 69.6 0.1 2.4 2 1 0 2 2 2 1 linker histone H1 and H5 family RHH_1 PF01402.21 RLN62086.1 - 0.15 12.1 0.3 0.88 9.6 0.2 2.1 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family CLU PF13236.6 RLN62087.1 - 4.7e-40 137.8 0.0 1e-39 136.6 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria LRR_6 PF13516.6 RLN62087.1 - 4.9e-17 60.5 16.6 0.015 15.3 0.0 12.1 12 0 0 12 12 12 5 Leucine Rich repeat Laminin_G_3 PF13385.6 RLN62087.1 - 4e-12 46.5 0.1 2.1e-10 40.9 0.0 2.8 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily eIF3_p135 PF12807.7 RLN62087.1 - 4.5e-07 30.1 0.0 4.5e-07 30.1 0.0 2.9 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 LRR_4 PF12799.7 RLN62087.1 - 2e-05 24.8 12.9 1.8 9.1 0.0 7.4 6 2 2 8 8 8 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN62087.1 - 0.0028 18.0 16.7 47 5.1 0.0 9.0 9 1 0 9 9 9 0 Leucine Rich Repeat His_Phos_1 PF00300.22 RLN62088.1 - 1.5e-08 34.5 0.0 9.6e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) ASF1_hist_chap PF04729.13 RLN62089.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 ASF1 like histone chaperone Trypsin_2 PF13365.6 RLN62090.1 - 2.9e-19 70.5 0.4 1.3e-18 68.3 0.1 2.0 2 0 0 2 2 2 1 Trypsin-like peptidase domain Peptidase_S46 PF10459.9 RLN62090.1 - 0.00025 19.8 1.9 0.0048 15.6 0.3 2.1 2 0 0 2 2 2 2 Peptidase S46 Trypsin_2 PF13365.6 RLN62091.1 - 4e-18 66.8 0.1 1e-17 65.4 0.1 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain CUB PF00431.20 RLN62091.1 - 0.033 14.5 0.0 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 CUB domain Peptidase_S46 PF10459.9 RLN62091.1 - 0.061 12.0 1.9 0.73 8.4 0.3 2.1 2 0 0 2 2 2 0 Peptidase S46 DAGAT PF03982.13 RLN62092.1 - 8.5e-10 38.0 0.0 1.1e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DAGAT PF03982.13 RLN62093.1 - 3.1e-24 85.4 0.1 3.4e-11 42.6 0.0 3.0 2 1 1 3 3 3 3 Diacylglycerol acyltransferase CRM1_C PF08767.11 RLN62117.1 - 7.1e-117 390.1 5.9 5.9e-116 387.1 2.3 2.5 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 RLN62117.1 - 8.1e-31 107.1 12.9 4.4e-30 104.7 7.6 3.8 3 1 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_3 PF18787.1 RLN62117.1 - 3.3e-30 103.9 1.7 3.3e-30 103.9 1.7 2.1 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat_2 PF18784.1 RLN62117.1 - 4.8e-30 103.0 2.9 1.2e-29 101.7 2.9 1.8 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat PF18777.1 RLN62117.1 - 3.8e-17 61.5 0.3 8.1e-17 60.4 0.3 1.6 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat BID PF06393.11 RLN62117.1 - 0.047 13.2 0.1 0.4 10.2 0.1 2.5 2 0 0 2 2 2 0 BH3 interacting domain (BID) IBN_N PF03810.19 RLN62117.1 - 0.048 13.6 0.2 0.24 11.4 0.2 2.3 1 0 0 1 1 1 0 Importin-beta N-terminal domain WD40 PF00400.32 RLN62119.1 - 1.2e-10 41.8 0.0 0.0024 18.6 0.0 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN62119.1 - 0.0048 17.2 0.0 0.92 9.9 0.0 2.7 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RLN62119.1 - 0.0049 16.2 0.0 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain CxC6 PF18721.1 RLN62120.1 - 0.092 13.0 2.7 0.21 11.9 2.7 1.6 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases BSP_II PF05432.11 RLN62120.1 - 0.43 10.2 10.4 1.2 8.8 10.4 1.7 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TSGP1 PF07771.11 RLN62120.1 - 5.6 7.2 16.3 4.5 7.4 3.4 2.5 2 0 0 2 2 2 0 Tick salivary peptide group 1 DUF659 PF04937.15 RLN62128.1 - 4.8e-13 49.2 0.0 1.4e-12 47.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 RLN62128.1 - 9.2e-05 22.2 0.6 0.0002 21.1 0.6 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region LCM PF04072.14 RLN62129.1 - 1.2e-41 142.7 0.1 2.1e-41 142.0 0.1 1.4 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase fn3 PF00041.21 RLN62130.1 - 1.1e-10 41.6 4.5 1.3e-07 31.9 0.1 2.6 3 0 0 3 3 3 2 Fibronectin type III domain SAM_2 PF07647.17 RLN62130.1 - 4.1e-06 26.8 0.0 8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EF-hand_1 PF00036.32 RLN62130.1 - 8.9e-06 24.9 1.6 0.21 11.2 0.0 3.4 2 1 1 3 3 3 3 EF hand EF-hand_5 PF13202.6 RLN62130.1 - 6.4e-05 22.3 0.7 3.1 7.5 0.0 3.4 3 0 0 3 3 3 3 EF hand SAM_1 PF00536.30 RLN62130.1 - 7.4e-05 23.1 0.0 0.00013 22.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EF-hand_7 PF13499.6 RLN62130.1 - 0.00027 21.3 5.0 0.0014 19.0 5.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN62130.1 - 0.00041 20.1 2.8 4.9 7.4 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 RLN62130.1 - 0.0025 17.6 1.1 0.047 13.6 0.1 3.0 2 1 1 3 3 3 1 EF-hand domain pair BpuSI_N PF15516.6 RLN62130.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 BpuSI N-terminal domain fn3_4 PF16794.5 RLN62130.1 - 0.064 13.2 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 Fibronectin-III type domain LCM PF04072.14 RLN62131.1 - 2.8e-36 125.3 0.0 3.5e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase THF_DHG_CYH PF00763.23 RLN62131.1 - 0.039 14.2 0.0 0.092 13.0 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GSHPx PF00255.19 RLN62153.1 - 2.4e-38 130.0 0.6 5.4e-38 128.9 0.6 1.6 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 RLN62153.1 - 9.8e-08 32.0 0.0 2.5e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family FYVE PF01363.21 RLN62153.1 - 1.8e-05 24.8 9.1 3.5e-05 23.9 9.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger Redoxin PF08534.10 RLN62153.1 - 5.8e-05 22.8 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 Redoxin Myc_target_1 PF15179.6 RLN62153.1 - 0.077 12.9 4.1 0.17 11.7 4.1 1.5 1 0 0 1 1 1 0 Myc target protein 1 FYVE_2 PF02318.16 RLN62153.1 - 1.1 9.5 6.3 0.41 10.9 2.8 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger Voldacs PF03517.13 RLN62169.1 - 0.017 15.3 0.6 0.017 15.3 0.6 2.1 1 1 1 2 2 2 0 Regulator of volume decrease after cellular swelling PCI PF01399.27 RLN62170.1 - 8.9e-14 51.9 0.2 9.6e-13 48.6 0.0 2.6 2 1 0 2 2 2 1 PCI domain LPD5 PF18799.1 RLN62170.1 - 0.17 12.3 0.2 0.32 11.4 0.2 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 5 SepSecS PF05889.13 RLN62301.1 - 6e-102 341.2 0.2 1.8e-97 326.5 0.1 2.1 2 0 0 2 2 2 2 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 RLN62301.1 - 3.6e-05 23.2 0.2 5.1e-05 22.7 0.2 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 RLN62301.1 - 0.011 14.5 0.1 0.017 13.9 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain WD40 PF00400.32 RLN62302.1 - 8.3e-12 45.4 3.9 0.001 19.9 0.5 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat F-box-like PF12937.7 RLN62302.1 - 8.7e-05 22.3 0.2 0.00019 21.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RLN62302.1 - 0.00087 19.1 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain Arf PF00025.21 RLN62303.1 - 1.1e-28 99.8 0.3 5.5e-17 61.8 0.0 3.0 1 1 2 3 3 3 3 ADP-ribosylation factor family Snf7 PF03357.21 RLN62304.1 - 1.1e-36 126.0 7.4 1.3e-36 125.8 7.4 1.1 1 0 0 1 1 1 1 Snf7 DUF2730 PF10805.8 RLN62304.1 - 6.9e-05 22.9 1.5 0.2 11.8 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2730) Prefoldin_2 PF01920.20 RLN62304.1 - 0.022 14.7 14.7 0.21 11.6 0.7 3.0 2 1 1 3 3 3 0 Prefoldin subunit NPV_P10 PF05531.12 RLN62304.1 - 0.023 15.2 7.4 1.4 9.4 1.1 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Cytochrom_B562 PF07361.11 RLN62304.1 - 0.063 13.9 8.7 0.099 13.3 1.3 2.3 2 0 0 2 2 2 0 Cytochrome b562 DASH_Dam1 PF08653.10 RLN62304.1 - 0.2 11.5 2.1 1.4 8.8 0.3 2.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 XhlA PF10779.9 RLN62304.1 - 0.24 11.7 5.6 0.28 11.4 0.1 2.9 2 1 1 3 3 3 0 Haemolysin XhlA FapA PF03961.13 RLN62304.1 - 0.3 9.6 6.4 0.49 9.0 3.7 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A YlqD PF11068.8 RLN62304.1 - 0.45 10.9 8.0 0.62 10.4 2.2 2.2 2 0 0 2 2 2 0 YlqD protein Spc7 PF08317.11 RLN62304.1 - 0.51 9.2 12.4 2.1 7.1 3.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 RLN62304.1 - 0.63 10.1 8.8 2.3 8.3 2.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Swi5 PF07061.11 RLN62304.1 - 0.67 10.1 10.2 0.92 9.6 0.5 3.1 2 1 1 3 3 3 0 Swi5 Vps54_N PF10475.9 RLN62304.1 - 0.71 9.1 5.8 1 8.6 5.8 1.2 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex CorA PF01544.18 RLN62304.1 - 0.96 8.7 5.7 9.4 5.4 5.7 2.0 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF16 PF01519.16 RLN62304.1 - 1 9.9 8.5 2 8.9 1.9 2.7 1 1 2 3 3 3 0 Protein of unknown function DUF16 V_ATPase_I PF01496.19 RLN62304.1 - 1.1 7.1 5.5 2 6.2 5.6 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 RLN62304.1 - 1.1 9.7 7.1 2.9 8.4 0.2 3.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) FliD_N PF02465.18 RLN62304.1 - 1.2 9.9 5.7 0.85 10.4 0.3 2.4 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF848 PF05852.11 RLN62304.1 - 1.6 8.9 7.3 0.63 10.1 2.8 2.1 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Remorin_C PF03763.13 RLN62304.1 - 3.3 7.6 9.0 6.5 6.7 0.3 2.7 1 1 2 3 3 3 0 Remorin, C-terminal region SlyX PF04102.12 RLN62304.1 - 3.7 8.2 10.4 0.62 10.7 0.6 3.0 2 2 1 3 3 3 0 SlyX ERM PF00769.19 RLN62304.1 - 4.1 7.2 16.0 6.5 6.5 2.1 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family EMP24_GP25L PF01105.24 RLN62304.1 - 4.2 7.3 5.5 7.1 6.5 0.4 2.1 1 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF2203 PF09969.9 RLN62304.1 - 4.3 8.1 6.2 3.8 8.3 0.4 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Phe_tRNA-synt_N PF02912.18 RLN62304.1 - 4.6 7.3 9.7 0.46 10.5 4.4 2.1 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain YabA PF06156.13 RLN62304.1 - 5 7.8 8.8 15 6.3 2.1 2.5 1 1 1 2 2 2 0 Initiation control protein YabA DUF724 PF05266.14 RLN62304.1 - 6.5 6.5 11.6 20 4.9 4.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ABC_tran_CTD PF16326.5 RLN62304.1 - 8.7 6.7 18.2 2.4 8.5 1.3 3.0 2 2 0 2 2 2 0 ABC transporter C-terminal domain Gp_dh_C PF02800.20 RLN62310.1 - 0.0078 15.8 0.1 0.022 14.4 0.0 1.7 2 1 1 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DUF418 PF04235.12 RLN62311.1 - 0.031 14.2 0.3 0.043 13.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF418) ADIP PF11559.8 RLN62312.1 - 0.015 15.4 13.4 0.015 15.4 13.4 5.3 1 1 5 6 6 6 0 Afadin- and alpha -actinin-Binding Vac_Fusion PF02346.16 RLN62312.1 - 0.027 14.1 0.5 0.027 14.1 0.5 3.9 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 TMF_DNA_bd PF12329.8 RLN62312.1 - 5.7 7.0 44.4 0.37 10.8 1.1 6.2 3 2 2 5 5 5 0 TATA element modulatory factor 1 DNA binding SAM_decarbox PF01536.16 RLN62363.1 - 1.1e-62 212.1 0.0 1.2e-62 212.0 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase bZIP_1 PF00170.21 RLN62364.1 - 0.00058 19.9 1.2 0.00093 19.3 1.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RLN62364.1 - 0.0026 17.8 2.9 0.0036 17.3 2.0 1.7 1 1 0 1 1 1 1 Basic region leucine zipper NRBF2 PF08961.10 RLN62364.1 - 0.0054 16.4 1.2 0.024 14.2 1.2 1.9 1 1 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator ATG16 PF08614.11 RLN62364.1 - 0.014 15.7 5.4 0.016 15.4 5.4 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) BST2 PF16716.5 RLN62364.1 - 0.019 15.6 2.9 0.024 15.2 2.6 1.4 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 CLZ PF16526.5 RLN62364.1 - 0.023 15.1 1.6 0.034 14.5 0.6 1.7 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DivIC PF04977.15 RLN62364.1 - 0.023 14.5 1.2 0.041 13.7 0.3 1.5 1 1 0 1 1 1 0 Septum formation initiator Jnk-SapK_ap_N PF09744.9 RLN62364.1 - 0.028 14.6 3.8 0.036 14.3 3.8 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Glyco_tran_28_C PF04101.16 RLN62364.1 - 0.036 14.1 0.6 0.051 13.5 0.6 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Cnn_1N PF07989.11 RLN62364.1 - 0.16 12.1 1.5 0.29 11.3 0.1 1.8 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF1664 PF07889.12 RLN62364.1 - 0.16 12.0 0.1 0.2 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 RLN62364.1 - 0.32 11.1 2.2 0.37 10.9 2.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus kleA_kleC PF17383.2 RLN62364.1 - 0.65 10.4 6.1 0.19 12.1 1.5 2.0 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A DIRP PF06584.13 RLN62365.1 - 6.9e-16 58.3 0.3 2.7e-15 56.5 0.1 2.1 2 0 0 2 2 2 1 DIRP Myb_DNA-binding PF00249.31 RLN62365.1 - 0.00061 19.9 0.0 0.0021 18.2 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN62365.1 - 0.0096 15.8 0.0 0.028 14.3 0.0 1.8 1 0 0 1 1 1 1 Myb DNA-binding like TFIID_30kDa PF03540.13 RLN62380.1 - 8.3e-22 76.9 0.1 1.5e-21 76.0 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Radical_SAM_C PF16199.5 RLN62380.1 - 0.038 14.0 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Radical_SAM C-terminal domain GAF_2 PF13185.6 RLN62381.1 - 0.0012 19.1 0.0 0.0013 19.0 0.0 1.0 1 0 0 1 1 1 1 GAF domain MatE PF01554.18 RLN62383.1 - 2.8e-57 192.9 34.1 1.2e-29 103.0 10.6 2.2 2 0 0 2 2 2 2 MatE LCAT PF02450.15 RLN62406.1 - 0.068 12.3 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 RLN62406.1 - 0.29 11.7 14.7 0.42 11.2 8.4 2.8 1 1 0 2 2 2 0 Alpha/beta hydrolase family MHYT PF03707.16 RLN62442.1 - 2.4e-26 91.7 27.6 1.2e-13 51.0 0.5 3.6 3 1 0 3 3 3 3 Bacterial signalling protein N terminal repeat SUR7 PF06687.12 RLN62442.1 - 0.061 12.9 7.9 0.16 11.6 7.9 1.8 1 1 0 1 1 1 0 SUR7/PalI family DUF4407 PF14362.6 RLN62442.1 - 0.56 9.5 3.7 1.3 8.3 3.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MHYT PF03707.16 RLN62443.1 - 5.7e-26 90.4 11.4 1.3e-13 50.9 0.3 2.4 2 0 0 2 2 2 2 Bacterial signalling protein N terminal repeat UPF0220 PF05255.11 RLN62443.1 - 0.00038 20.0 2.2 0.00056 19.5 2.2 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Tox-WTIP PF15654.6 RLN62443.1 - 0.17 12.3 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif SUR7 PF06687.12 RLN62443.1 - 0.37 10.4 8.8 1.9 8.1 8.8 1.9 1 1 0 1 1 1 0 SUR7/PalI family DUF2975 PF11188.8 RLN62443.1 - 1.6 8.6 13.1 1.4 8.8 1.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) Phage_holin_3_6 PF07332.11 RLN62443.1 - 3.3 7.8 12.2 1.7 8.7 3.7 2.4 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III PX PF00787.24 RLN62444.1 - 1e-06 28.7 0.0 1.5e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 PX domain Inositol_P PF00459.25 RLN62445.1 - 4.9e-34 118.1 0.0 7.9e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family EcKinase PF02958.20 RLN62445.1 - 7.3e-16 58.3 0.0 3e-15 56.3 0.0 1.9 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 RLN62445.1 - 2.6e-08 33.2 0.1 4.3e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 RLN62445.1 - 2.3e-05 24.5 6.9 9.4e-05 22.4 6.9 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 RLN62445.1 - 0.0055 16.3 0.0 0.0084 15.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Zip PF02535.22 RLN62447.1 - 2.6e-26 92.6 21.3 2.5e-25 89.4 21.3 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Glucokinase PF02685.16 RLN62448.1 - 3.2e-206 683.4 0.0 4e-81 272.5 0.0 3.0 3 0 0 3 3 3 3 Glucokinase VDE PF07137.11 RLN62448.1 - 0.033 13.7 0.0 27 4.2 0.0 3.1 3 0 0 3 3 3 0 VDE lipocalin domain FeoB_N PF02421.18 RLN62448.1 - 0.038 13.5 0.0 13 5.2 0.0 3.1 3 0 0 3 3 3 0 Ferrous iron transport protein B T3SS_LEE_assoc PF13327.6 RLN62448.1 - 0.072 13.1 0.7 42 4.1 0.0 3.3 3 0 0 3 3 3 0 Type III secretion system subunit His_binding PF02098.16 RLN62448.1 - 0.12 12.4 0.2 17 5.4 0.0 2.6 3 0 0 3 3 3 0 Tick histamine binding protein DUF4501 PF14946.6 RLN62448.1 - 0.14 12.2 0.2 50 3.9 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4501) CMV_1a PF12467.8 RLN62448.1 - 0.26 11.6 0.3 34 4.7 0.0 2.4 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family Plasmod_Pvs28 PF06247.11 RLN62448.1 - 2.4 8.6 4.4 72 3.8 0.1 3.3 3 0 0 3 3 3 0 Pvs28 EGF domain MHYT PF03707.16 RLN62449.1 - 3.7e-27 94.3 24.1 2.7e-13 49.9 0.3 3.6 3 1 0 3 3 3 3 Bacterial signalling protein N terminal repeat SUR7 PF06687.12 RLN62449.1 - 0.059 13.0 7.1 0.14 11.8 7.1 1.7 1 1 0 1 1 1 0 SUR7/PalI family DUF4407 PF14362.6 RLN62449.1 - 0.54 9.6 3.7 1.3 8.3 3.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PX PF00787.24 RLN62450.1 - 6.3e-06 26.1 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 PX domain MtrB_PioB PF11854.8 RLN62450.1 - 0.032 12.6 0.1 0.042 12.2 0.1 1.1 1 0 0 1 1 1 0 Putative outer membrane beta-barrel porin, MtrB/PioB IQ PF00612.27 RLN62451.1 - 1e-12 46.7 123.3 0.00057 19.5 0.1 17.0 17 1 1 18 18 18 10 IQ calmodulin-binding motif LRR_6 PF13516.6 RLN62451.1 - 1.4e-06 27.9 17.5 0.096 12.8 0.0 7.6 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.7 RLN62451.1 - 4.9e-05 23.6 7.8 0.33 11.5 0.0 5.1 3 2 3 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN62451.1 - 0.015 15.1 0.4 5.6 6.8 0.0 3.6 3 0 0 3 3 3 0 Leucine rich repeat DUF1319 PF07028.11 RLN62451.1 - 0.078 13.2 0.8 0.24 11.6 0.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) 4HBT PF03061.22 RLN62452.1 - 4.2e-13 49.4 0.2 6.2e-13 48.9 0.2 1.2 1 0 0 1 1 1 1 Thioesterase superfamily YiiD_C PF09500.10 RLN62452.1 - 0.042 13.7 0.1 0.072 12.9 0.1 1.5 1 1 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) Rapsyn_N PF10579.9 RLN62452.1 - 0.072 13.2 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region MHYT PF03707.16 RLN62453.1 - 2.2e-24 85.4 11.8 2.7e-11 43.4 0.1 3.7 3 0 0 3 3 3 3 Bacterial signalling protein N terminal repeat LPAM_2 PF13627.6 RLN62453.1 - 0.28 11.1 2.3 1.1 9.2 2.3 2.1 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Ank_2 PF12796.7 RLN62489.1 - 1.6e-27 95.9 0.9 5.4e-13 49.3 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN62489.1 - 4.5e-21 74.9 0.1 1e-09 38.8 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN62489.1 - 7.6e-21 72.0 2.8 2.3e-05 24.4 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 RLN62489.1 - 1.7e-19 69.3 4.7 2.3e-05 24.6 0.1 6.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 RLN62489.1 - 1.6e-18 66.5 1.0 9.6e-10 38.5 0.1 4.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Pkinase PF00069.25 RLN62489.1 - 9.5e-12 44.8 0.0 2.7e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN62489.1 - 4.9e-10 39.1 0.1 1.4e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase WW PF00397.26 RLN62489.1 - 1.5e-05 25.0 0.1 3.2e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 WW domain Kisspeptin PF15152.6 RLN62489.1 - 0.0047 17.7 0.1 0.028 15.2 0.1 2.4 1 0 0 1 1 1 1 Kisspeptin DUF4468 PF14730.6 RLN62489.1 - 0.038 14.3 0.4 0.094 13.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4468) with TBP-like fold Ipi1_N PF12333.8 RLN62489.1 - 0.072 13.7 2.2 0.83 10.3 0.0 3.8 3 0 0 3 3 2 0 Rix1 complex component involved in 60S ribosome maturation Glyco_hyd_101C PF17451.2 RLN62489.1 - 0.099 12.9 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain PQQ PF01011.21 RLN62489.1 - 0.19 11.7 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 PQQ enzyme repeat HEAT PF02985.22 RLN62489.1 - 1.1 9.7 20.1 37 4.9 0.3 9.0 11 0 0 11 11 10 0 HEAT repeat HEAT_EZ PF13513.6 RLN62489.1 - 1.7 9.2 5.9 30 5.2 0.0 5.4 6 0 0 6 6 5 0 HEAT-like repeat BCNT PF07572.12 RLN62490.1 - 2.3e-19 69.2 1.1 2.3e-19 69.2 1.1 2.0 2 1 0 2 2 2 1 Bucentaur or craniofacial development Hist_deacetyl PF00850.19 RLN62491.1 - 8.4e-74 248.8 0.1 1.1e-73 248.4 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Exo_endo_phos PF03372.23 RLN62492.1 - 5.7e-17 62.0 0.0 8.4e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-PARP PF00645.18 RLN62492.1 - 2.2e-10 41.2 0.3 2.2e-10 41.2 0.3 2.0 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region ABC2_membrane PF01061.24 RLN62493.1 - 1.8e-66 223.6 68.3 1e-37 129.7 19.6 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN62493.1 - 5.9e-17 62.5 0.0 1e-16 61.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter PDR_CDR PF06422.12 RLN62493.1 - 8.5e-08 32.0 0.9 9.6e-05 22.2 0.0 3.9 5 0 0 5 5 4 2 CDR ABC transporter PDR_assoc PF08370.11 RLN62493.1 - 7.5e-07 28.8 0.7 7.5e-07 28.8 0.7 3.8 3 0 0 3 3 2 1 Plant PDR ABC transporter associated AAA_21 PF13304.6 RLN62493.1 - 9.5e-07 28.9 0.0 0.0022 17.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 RLN62493.1 - 5.3e-06 25.8 53.9 4.1e-05 22.9 19.0 3.0 3 1 1 4 4 4 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 RLN62493.1 - 0.0017 18.3 0.8 0.013 15.4 0.5 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 RLN62493.1 - 0.0045 16.7 1.2 0.013 15.2 1.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN62493.1 - 0.038 14.4 0.0 0.072 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 RLN62493.1 - 0.095 12.1 0.3 1.1 8.7 0.3 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RLN62493.1 - 0.18 12.3 0.3 0.35 11.3 0.3 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RLN62493.1 - 0.23 11.0 0.2 0.46 10.0 0.2 1.4 1 0 0 1 1 1 0 AAA domain Trehalase PF01204.18 RLN62494.1 - 2.1e-136 455.8 0.1 2.4e-136 455.6 0.1 1.0 1 0 0 1 1 1 1 Trehalase Glyco_hydro_63 PF03200.16 RLN62494.1 - 2.2e-05 23.4 2.3 0.0062 15.4 0.2 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain IF4E PF01652.18 RLN62495.1 - 2.3e-24 86.0 0.0 2.8e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DEAD PF00270.29 RLN62496.1 - 7.8e-49 165.8 0.0 1.7e-48 164.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN62496.1 - 8.5e-25 87.3 0.0 1.1e-23 83.7 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain GUCT PF08152.12 RLN62496.1 - 7e-23 80.7 0.0 2.1e-22 79.2 0.0 1.9 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.15 RLN62496.1 - 4.1e-07 30.2 1.8 1.2e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 RLN62496.1 - 0.21 10.9 12.1 2.2 7.5 0.0 2.5 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit TFIIF_alpha PF05793.12 RLN62496.1 - 0.59 8.7 25.6 0.93 8.0 25.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Glyco_transf_20 PF00982.21 RLN62512.1 - 1.1e-114 383.8 0.0 1.6e-114 383.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 RLN62512.1 - 1.8e-33 115.6 0.0 8.2e-33 113.5 0.0 2.2 2 1 0 2 2 2 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 RLN62512.1 - 0.15 11.7 0.1 0.27 10.9 0.1 1.3 1 0 0 1 1 1 0 Starch synthase catalytic domain UQ_con PF00179.26 RLN62514.1 - 1.4e-33 115.5 0.0 2.1e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FWWh PF14922.6 RLN62515.1 - 1.8e-36 125.3 0.2 3e-36 124.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function UCH PF00443.29 RLN62516.1 - 1.1e-74 251.2 0.0 1.5e-74 250.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN62516.1 - 3.7e-16 59.6 1.4 2.8e-08 33.7 1.2 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 RLN62516.1 - 2.4e-14 53.7 0.0 5.7e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 DUSP domain Raftlin PF15250.6 RLN62516.1 - 0.42 9.3 8.0 2.1 7.0 7.6 1.9 2 0 0 2 2 2 0 Raftlin CDC45 PF02724.14 RLN62516.1 - 1.6 6.9 17.9 5.7 5.1 12.5 2.1 2 0 0 2 2 2 0 CDC45-like protein Na_trans_assoc PF06512.13 RLN62516.1 - 3.2 8.0 13.2 72 3.6 0.0 2.3 2 0 0 2 2 2 0 Sodium ion transport-associated DUF2052 PF09747.9 RLN62516.1 - 4.2 7.4 19.8 27 4.8 0.1 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) WW PF00397.26 RLN62517.1 - 0.0041 17.2 0.1 0.0089 16.1 0.1 1.6 1 0 0 1 1 1 1 WW domain DUF594 PF04578.13 RLN62517.1 - 0.0099 15.4 0.4 0.071 12.7 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF594 CDC45 PF02724.14 RLN62517.1 - 0.013 13.8 9.9 0.019 13.3 9.9 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 RLN62517.1 - 0.021 14.5 0.5 0.047 13.3 0.5 1.6 1 0 0 1 1 1 0 FAM176 family PTPRCAP PF15713.5 RLN62517.1 - 0.056 13.7 7.8 0.1 12.9 7.8 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SDA1 PF05285.12 RLN62517.1 - 0.15 11.5 8.6 0.21 11.0 8.6 1.1 1 0 0 1 1 1 0 SDA1 Nop53 PF07767.11 RLN62517.1 - 0.16 11.3 8.5 0.24 10.7 8.5 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2231 PF09990.9 RLN62517.1 - 0.17 12.4 4.6 0.12 12.9 0.9 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) B2-adapt-app_C PF09066.10 RLN62517.1 - 0.19 11.8 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain SPW PF03779.14 RLN62517.1 - 1.6 8.4 7.5 0.9 9.2 4.1 2.3 2 0 0 2 2 2 0 SPW repeat Sigma70_ner PF04546.13 RLN62517.1 - 1.7 8.5 5.4 2.7 7.8 5.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 RLN62517.1 - 1.9 6.5 12.6 2.7 6.0 12.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi CCDC106 PF15794.5 RLN62517.1 - 4.9 6.8 5.2 8.5 6.0 5.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 rRNA_processing PF08524.11 RLN62517.1 - 4.9 7.2 4.6 7.7 6.5 4.6 1.2 1 0 0 1 1 1 0 rRNA processing zf-C2H2_aberr PF17017.5 RLN62555.1 - 0.013 15.7 1.3 0.11 12.6 0.1 2.2 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2 PF00096.26 RLN62555.1 - 0.3 11.6 3.2 4.6 7.9 0.9 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Kinesin PF00225.23 RLN62666.1 - 7.2e-101 337.4 0.0 1.2e-100 336.8 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN62666.1 - 2.5e-20 72.9 0.0 1.8e-19 70.2 0.0 2.3 1 1 0 1 1 1 1 Microtubule binding FAM60A PF15396.6 RLN62666.1 - 2.1 8.3 5.9 0.34 10.9 0.7 2.1 1 1 1 2 2 2 0 Protein Family FAM60A PPR_3 PF13812.6 RLN62667.1 - 1.5e-05 25.0 0.0 0.0024 17.9 0.0 2.5 1 1 1 2 2 2 2 Pentatricopeptide repeat domain PPR_long PF17177.4 RLN62667.1 - 0.00019 20.9 0.1 0.00063 19.2 0.1 1.7 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 RLN62667.1 - 0.015 15.5 0.0 1.1 9.5 0.0 3.2 3 1 1 4 4 4 0 PPR repeat family PPR PF01535.20 RLN62667.1 - 0.094 13.0 0.0 29 5.2 0.0 3.3 3 0 0 3 3 3 0 PPR repeat TPR_14 PF13428.6 RLN62667.1 - 0.51 11.3 6.5 1.2 10.1 0.6 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 RLN62668.1 - 1.2e-11 44.4 0.0 1.7e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN62668.1 - 2e-08 33.9 0.0 3.5e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DZR PF12773.7 RLN62668.1 - 0.00029 20.8 0.8 0.00061 19.8 0.8 1.6 1 1 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 RLN62668.1 - 0.013 16.3 0.1 0.034 14.9 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon family zinc-ribbon_6 PF10005.9 RLN62668.1 - 0.016 15.9 0.6 0.031 14.9 0.6 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 RLN62668.1 - 0.041 13.6 2.9 0.54 10.1 3.7 2.3 1 1 1 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 RLN62668.1 - 0.15 11.5 2.0 0.41 10.1 2.0 1.8 1 0 0 1 1 1 0 zinc-ribbon domain C1_1 PF00130.22 RLN62668.1 - 4.1 7.4 6.4 9.6 6.2 1.5 2.8 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OSCP PF00213.18 RLN62695.1 - 5.4e-36 124.3 2.1 9.7e-36 123.5 2.1 1.4 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit TFIIA_gamma_N PF02268.16 RLN62695.1 - 0.00085 19.3 0.2 0.0018 18.2 0.2 1.6 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain RNase_PH PF01138.21 RLN62696.1 - 4e-13 50.0 0.0 4.9e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 NAM-associated PF14303.6 RLN62723.1 - 0.00014 22.6 13.6 0.00044 21.0 0.4 3.5 3 0 0 3 3 3 2 No apical meristem-associated C-terminal domain DUF3328 PF11807.8 RLN62723.1 - 0.0078 16.0 0.0 2.4 7.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3328) Rap1_C PF11626.8 RLN62723.1 - 0.049 13.7 4.4 15 5.8 2.6 3.3 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Med27 PF11571.8 RLN62724.1 - 7.5e-20 71.1 1.9 8.2e-20 71.0 1.9 1.0 1 0 0 1 1 1 1 Mediator complex subunit 27 Dus PF01207.17 RLN62725.1 - 4.8e-60 203.2 0.0 7.6e-60 202.6 0.0 1.2 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Glyco_hydro_18 PF00704.28 RLN62725.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 2 0 0 2 2 2 0 Glycosyl hydrolases family 18 ATPgrasp_ST PF14397.6 RLN62727.1 - 2.9e-12 46.4 0.1 5.1e-11 42.4 0.1 2.5 1 1 1 2 2 2 1 Sugar-transfer associated ATP-grasp LPD3 PF18798.1 RLN62727.1 - 0.078 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 3 LRR_6 PF13516.6 RLN62728.1 - 2.5e-11 42.7 0.6 0.12 12.5 0.0 6.1 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 RLN62728.1 - 1.9e-06 28.1 0.0 0.016 15.6 0.0 4.6 5 2 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN62728.1 - 0.0035 17.7 0.2 19 6.3 0.0 5.2 6 0 0 6 6 6 1 Leucine Rich Repeat F-box-like PF12937.7 RLN62728.1 - 0.016 15.1 0.2 0.032 14.1 0.2 1.5 1 0 0 1 1 1 0 F-box-like TFIID-18kDa PF02269.16 RLN62729.1 - 3e-15 56.0 0.1 5.2e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit ASF1_hist_chap PF04729.13 RLN62731.1 - 1.7e-56 190.5 0.1 3.9e-56 189.3 0.1 1.6 1 1 0 1 1 1 1 ASF1 like histone chaperone Methyltransf_25 PF13649.6 RLN62732.1 - 8.2e-13 48.9 0.0 2.5e-12 47.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RLN62732.1 - 6.9e-11 42.1 0.0 9.8e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 RLN62732.1 - 4.4e-10 39.6 0.0 1e-09 38.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN62732.1 - 1.2e-09 38.7 0.1 3.8e-09 37.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 RLN62732.1 - 5.2e-07 28.9 0.1 7.1e-07 28.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 RLN62732.1 - 2.1e-06 27.7 0.0 6.2e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 RLN62732.1 - 2.1e-06 27.2 0.0 2.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 RLN62732.1 - 3.6e-06 27.6 0.0 6.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 RLN62732.1 - 8.1e-06 25.8 0.1 1.5e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN62732.1 - 5e-05 22.9 0.1 7.7e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 RLN62732.1 - 0.00065 19.1 0.0 0.00099 18.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 RLN62732.1 - 0.0011 19.1 0.4 0.0057 16.8 0.4 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 RLN62732.1 - 0.0047 16.9 0.0 0.0072 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 RLN62732.1 - 0.0065 16.2 0.1 0.0095 15.7 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRMT5 PF05185.16 RLN62732.1 - 0.027 14.3 0.1 0.053 13.4 0.1 1.4 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_16 PF10294.9 RLN62732.1 - 0.036 13.8 0.1 0.057 13.2 0.1 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 RLN62732.1 - 0.084 12.2 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Met_10 PF02475.16 RLN62732.1 - 0.085 12.6 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_24 PF13578.6 RLN62732.1 - 0.092 13.8 0.0 0.16 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 RLN62732.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 RLN62732.1 - 0.15 11.6 0.1 0.35 10.4 0.0 1.6 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Ribosomal_L24e PF01246.20 RLN62733.1 - 5.9e-26 90.5 1.1 1.1e-25 89.6 1.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e HZS_alpha PF18582.1 RLN62733.1 - 0.085 13.3 0.1 0.33 11.5 0.0 1.8 1 1 1 2 2 2 0 Hydrazine synthase alpha subunit middle domain Aminotran_1_2 PF00155.21 RLN62734.1 - 1.6e-15 57.2 0.0 6.5e-13 48.6 0.0 2.8 1 1 1 2 2 2 2 Aminotransferase class I and II Aminotran_MocR PF12897.7 RLN62734.1 - 2.2e-09 36.6 0.0 2.2e-07 30.1 0.0 2.1 1 1 0 2 2 2 2 Alanine-glyoxylate amino-transferase MULE PF10551.9 RLN62762.1 - 1.2e-07 32.1 0.1 2.8e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain Peptidase_C48 PF02902.19 RLN62762.1 - 2.7e-06 27.4 0.1 5.4e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SWIM PF04434.17 RLN62762.1 - 0.025 14.2 2.6 0.055 13.2 2.6 1.5 1 0 0 1 1 1 0 SWIM zinc finger ABC_membrane PF00664.23 RLN62800.1 - 1.6e-48 165.8 27.1 7.5e-26 91.4 5.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN62800.1 - 3.6e-19 69.6 0.0 6.9e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 RLN62800.1 - 0.0026 18.1 0.0 0.0066 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RLN62800.1 - 0.012 15.9 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 RLN62800.1 - 0.014 15.8 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 RLN62800.1 - 0.046 13.3 0.0 0.43 10.2 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 RLN62800.1 - 0.069 12.6 0.0 1.8 7.9 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ATPase_2 PF01637.18 RLN62800.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea VPS13_C PF16909.5 RLN62801.1 - 7.4e-56 188.7 6.3 1.9e-53 180.9 0.5 2.4 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 RLN62801.1 - 4.8e-32 111.6 0.0 2.2e-30 106.2 0.0 3.4 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 RLN62801.1 - 1.1e-28 99.6 0.0 3.9e-28 97.9 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 RLN62801.1 - 1e-14 54.6 0.0 2.9e-11 43.2 0.0 2.7 1 1 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 Apt1 PF10351.9 RLN62801.1 - 0.0024 16.8 0.0 0.0064 15.4 0.0 1.7 1 0 0 1 1 1 1 Golgi-body localisation protein domain ATG_C PF09333.11 RLN62801.1 - 0.0025 18.1 0.9 0.008 16.5 0.9 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain FYVE PF01363.21 RLN62804.1 - 1.9e-11 43.9 7.0 3.9e-11 42.9 7.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN62804.1 - 0.0016 18.6 4.5 0.0059 16.8 4.5 2.0 1 0 0 1 1 1 1 FYVE-type zinc finger HypA PF01155.19 RLN62804.1 - 0.067 13.2 2.8 0.065 13.3 1.0 1.9 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_1 PF00130.22 RLN62804.1 - 0.2 11.6 5.7 0.042 13.7 2.0 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_L40e PF01020.17 RLN62804.1 - 0.4 10.6 4.0 0.98 9.4 4.0 1.6 1 0 0 1 1 1 0 Ribosomal L40e family zinc_ribbon_4 PF13717.6 RLN62804.1 - 1.9 8.5 8.4 9 6.3 0.5 3.4 2 1 1 3 3 3 0 zinc-ribbon domain zf-B_box PF00643.24 RLN62804.1 - 8.2 6.7 5.9 28 5.0 5.9 1.9 1 1 0 1 1 1 0 B-box zinc finger Chorein_N PF12624.7 RLN62840.1 - 6.4e-22 77.9 0.0 2e-21 76.2 0.0 1.9 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG2_CAD PF13329.6 RLN62840.1 - 1.2e-07 31.6 0.0 5.2e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif TPK_catalytic PF04263.16 RLN62841.1 - 4.9e-39 133.1 0.4 6.5e-39 132.7 0.4 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 RLN62841.1 - 2.2e-17 62.5 0.0 3.4e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Mur_ligase_C PF02875.21 RLN62841.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain DUF1336 PF07059.12 RLN62842.1 - 6.4e-43 147.4 0.0 1.2e-42 146.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) PH PF00169.29 RLN62842.1 - 6.7e-08 33.0 0.4 0.0031 18.0 0.1 2.5 2 0 0 2 2 2 2 PH domain PH_8 PF15409.6 RLN62842.1 - 0.0014 18.8 0.1 0.031 14.5 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 RLN62842.1 - 0.0068 16.8 0.3 0.016 15.6 0.3 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PRIMA1 PF16101.5 RLN62842.1 - 0.19 11.8 1.9 0.47 10.5 1.9 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF4504 PF14953.6 RLN62843.1 - 9.3e-09 35.0 0.0 1.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4504) DDE_1 PF03184.19 RLN62867.1 - 0.052 13.2 0.0 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF3325 PF11804.8 RLN62873.1 - 0.32 11.2 3.8 2.5 8.3 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) SDF PF00375.18 RLN62874.1 - 5.9e-11 42.0 5.9 6.8e-11 41.8 5.9 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family PP2C PF00481.21 RLN62926.1 - 2e-54 185.0 2.3 1.6e-52 178.7 2.3 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RLN62926.1 - 2.9e-06 27.1 0.3 7.4e-06 25.7 0.3 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C AcylCoA_dehyd_C PF12186.8 RLN62926.1 - 0.00091 19.3 0.0 0.0021 18.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase C terminal SpoIIE PF07228.12 RLN62926.1 - 0.0054 16.7 0.1 2 8.3 0.0 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) YpsA PF06908.11 RLN62926.1 - 0.23 11.4 0.0 0.41 10.6 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family PDZ PF00595.24 RLN62927.1 - 0.0022 18.3 0.0 0.11 12.8 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 RLN62927.1 - 0.0071 16.2 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 RLN62927.1 - 0.067 13.5 0.0 0.42 11.0 0.0 2.2 2 0 0 2 2 2 0 PDZ domain Peptidase_A25 PF03418.14 RLN62927.1 - 0.13 11.1 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Germination protease Ank_2 PF12796.7 RLN62967.1 - 1.3e-36 125.1 8.4 1.4e-08 35.2 0.0 7.2 1 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN62967.1 - 1.7e-34 117.7 15.0 4.5e-06 27.1 0.0 10.4 7 3 5 12 12 12 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN62967.1 - 3.6e-33 113.2 22.1 0.0031 17.8 0.0 14.6 5 2 11 16 16 16 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN62967.1 - 1.8e-20 70.8 4.3 11 6.9 0.0 13.4 12 1 1 13 13 13 1 Ankyrin repeat DUF5049 PF16468.5 RLN62967.1 - 2.1e-05 24.3 0.3 18 5.3 0.0 7.0 6 1 4 10 10 10 1 Domain of unknown function (DUF5049) Ank PF00023.30 RLN62967.1 - 0.00026 21.3 2.7 1e+02 3.6 0.0 8.1 6 4 2 8 8 8 0 Ankyrin repeat Daxx PF03344.15 RLN62967.1 - 0.02 15.0 0.1 12 6.0 0.0 4.4 3 3 2 5 5 5 0 Daxx N-terminal Rassf1C-interacting domain DUF3425 PF11905.8 RLN62967.1 - 0.053 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3425) DUF1987 PF09345.10 RLN62967.1 - 6.4 6.5 12.6 3.6 7.3 0.0 5.7 4 2 3 8 8 8 0 Domain of unknown function (DUF1987) CENP-F_leu_zip PF10473.9 RLN63053.1 - 0.01 15.9 12.9 0.42 10.6 0.1 2.7 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4472 PF14739.6 RLN63053.1 - 0.29 11.9 0.2 0.29 11.9 0.2 3.7 3 1 2 5 5 5 0 Domain of unknown function (DUF4472) PPP4R2 PF09184.11 RLN63053.1 - 3.6 7.1 7.2 6 6.4 7.2 1.3 1 0 0 1 1 1 0 PPP4R2 Pinin_SDK_N PF04697.13 RLN63130.1 - 0.61 10.7 3.9 1.2 9.8 3.9 1.4 1 0 0 1 1 1 0 pinin/SDK conserved region RskA PF10099.9 RLN63152.1 - 0.078 13.3 2.9 0.085 13.1 2.9 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4131 PF13567.6 RLN63152.1 - 0.1 12.2 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MFAP1 PF06991.11 RLN63153.1 - 2.4e-44 151.8 45.0 3.5e-23 82.6 7.0 4.5 3 2 1 4 4 4 4 Microfibril-associated/Pre-mRNA processing DEAD PF00270.29 RLN63155.1 - 1.3e-35 122.8 0.1 2.2e-35 122.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN63155.1 - 8.4e-24 84.1 0.3 2.9e-23 82.3 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN63155.1 - 3.3e-05 24.0 0.0 6.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 RLN63155.1 - 8.7e-05 22.0 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit MAGE PF01454.19 RLN63156.1 - 7.7e-09 35.6 0.1 7.1e-07 29.1 0.0 2.5 2 1 1 3 3 3 2 MAGE family HVSL PF09749.9 RLN63157.1 - 1.6e-22 80.1 0.0 7.4e-18 64.9 0.0 2.1 1 1 1 2 2 2 2 Uncharacterised conserved protein CSN5_C PF18323.1 RLN63158.1 - 2.1e-07 31.8 0.3 2.4e-07 31.6 0.3 1.1 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain FHA PF00498.26 RLN63159.1 - 1.5e-12 47.6 0.4 3.6e-12 46.4 0.1 1.8 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 RLN63159.1 - 0.0014 18.9 0.0 0.025 14.9 0.0 2.6 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF3623 PF12291.8 RLN63159.1 - 0.015 14.5 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3623) RTT107_BRCT_5 PF16770.5 RLN63159.1 - 0.031 14.1 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Crystall PF00030.19 RLN63161.1 - 0.042 14.1 0.2 0.16 12.2 0.2 2.0 1 1 0 1 1 1 0 Beta/Gamma crystallin RNF220 PF15926.5 RLN63162.1 - 0.0016 18.1 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 Reoviridae_Vp9 PF08978.10 RLN63162.1 - 0.19 10.8 1.0 0.34 10.0 1.0 1.3 1 0 0 1 1 1 0 Reoviridae VP9 SfLAP PF11139.8 RLN63162.1 - 0.2 11.1 3.3 2.2 7.7 0.0 2.9 3 1 0 3 3 3 0 Sap, sulfolipid-1-addressing protein LRR_8 PF13855.6 RLN63162.1 - 1.8 8.4 4.0 5.7 6.8 0.1 3.0 3 0 0 3 3 3 0 Leucine rich repeat PWWP PF00855.17 RLN63163.1 - 4.9e-16 58.9 0.1 1.7e-15 57.1 0.1 2.1 1 0 0 1 1 1 1 PWWP domain JAB PF01398.21 RLN63163.1 - 4.4e-09 36.3 0.0 1.6e-08 34.5 0.0 2.0 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 RLN63163.1 - 8.2e-07 28.8 0.0 2.7e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Cupin_8 PF13621.6 RLN63164.1 - 0.087 12.5 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Cupin-like domain Med26 PF08711.11 RLN63165.1 - 0.00055 19.9 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF3430 PF11912.8 RLN63166.1 - 0.0017 18.4 6.5 0.0023 18.0 6.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Myticin-prepro PF10690.9 RLN63166.1 - 0.0084 16.3 0.5 0.015 15.5 0.1 1.7 2 0 0 2 2 2 1 Myticin pre-proprotein from the mussel META PF03724.16 RLN63177.1 - 0.045 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 META domain DUF4407 PF14362.6 RLN63178.1 - 0.18 11.1 2.7 0.25 10.7 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 RLN63178.1 - 0.39 11.1 7.3 0.58 10.5 7.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 RLN63178.1 - 5 6.6 7.9 7.2 6.1 7.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-C2HC_2 PF13913.6 RLN63179.1 - 0.0036 17.2 4.6 0.0071 16.2 3.5 2.1 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-Di19 PF05605.12 RLN63179.1 - 6.6 7.1 11.3 0.062 13.6 2.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Lactamase_B_6 PF16661.5 RLN63180.1 - 9.8e-45 152.4 0.0 1.6e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 RLN63180.1 - 9.5e-20 71.5 3.4 2.8e-17 63.4 0.1 3.2 2 1 1 3 3 3 2 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.12 RLN63180.1 - 1.6e-08 34.4 0.0 3.1e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 RLN63180.1 - 3.8e-06 27.0 0.2 6.8e-06 26.2 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 RLN63180.1 - 0.0053 16.3 0.0 0.017 14.7 0.0 1.9 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Ribosomal_L25p PF01386.19 RLN63181.1 - 1.8e-17 63.6 0.0 2.3e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal L25p family MLTD_N PF06474.12 RLN63181.1 - 0.25 11.5 3.3 0.26 11.5 1.7 1.9 2 0 0 2 2 2 0 MltD lipid attachment motif Zn-ribbon_8 PF09723.10 RLN63184.1 - 0.0059 16.7 1.6 1.8 8.7 0.2 2.7 2 0 0 2 2 2 2 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 RLN63184.1 - 0.02 14.9 2.1 0.044 13.8 2.1 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DZR PF12773.7 RLN63184.1 - 0.13 12.3 2.3 0.31 11.1 2.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon YhfH PF14149.6 RLN63184.1 - 0.75 9.8 7.2 9.4 6.3 1.7 2.6 2 0 0 2 2 2 0 YhfH-like protein zf-Mss51 PF13824.6 RLN63184.1 - 1.3 9.2 5.0 5.1 7.3 5.0 2.1 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 SNARE_assoc PF09335.11 RLN63186.1 - 9.9e-12 45.4 2.0 2.3e-10 41.0 1.2 2.7 2 0 0 2 2 2 1 SNARE associated Golgi protein Oxysterol_BP PF01237.18 RLN63187.1 - 9.5e-39 133.3 0.0 4.1e-36 124.6 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein ParA PF10609.9 RLN63188.1 - 9.2e-58 195.6 0.4 1.2e-57 195.2 0.4 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 RLN63188.1 - 2.6e-12 46.9 0.0 3.5e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 RLN63188.1 - 4.4e-12 46.3 0.1 9e-10 38.7 0.0 2.1 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 RLN63188.1 - 1.6e-07 30.9 0.3 6.6e-07 28.9 0.3 2.0 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 RLN63188.1 - 8.8e-07 28.6 0.1 1.2e-06 28.2 0.1 1.1 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 RLN63188.1 - 0.00027 20.2 0.5 0.00066 18.9 0.2 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 RLN63188.1 - 0.00043 19.7 0.0 0.00077 18.8 0.0 1.4 1 0 0 1 1 1 1 VirC1 protein CBP_BcsQ PF06564.12 RLN63188.1 - 0.0054 16.2 0.1 0.018 14.5 0.1 1.8 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 RLN63188.1 - 0.011 14.7 0.1 0.021 13.8 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 RLN63188.1 - 0.02 14.7 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop FeS_assembly_P PF01883.19 RLN63188.1 - 0.073 13.3 0.2 1.5 9.0 0.2 2.6 1 1 1 2 2 2 0 Iron-sulfur cluster assembly protein DUF4499 PF14934.6 RLN63212.1 - 0.014 15.7 0.3 0.044 14.1 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4499) AAA PF00004.29 RLN63252.1 - 2e-54 183.6 4.3 1.8e-13 51.1 0.1 5.2 5 0 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 RLN63252.1 - 9e-30 103.8 0.0 3.1e-29 102.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_lid_6 PF17866.1 RLN63252.1 - 1.5e-24 85.9 6.9 1.4e-06 28.4 0.3 5.9 5 0 0 5 5 5 4 AAA lid domain RuvB_N PF05496.12 RLN63252.1 - 2.6e-15 56.5 0.9 0.0051 16.6 0.0 4.6 4 0 0 4 4 4 3 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RLN63252.1 - 5.7e-14 52.6 15.9 0.023 15.0 0.0 10.0 7 4 1 8 8 6 3 AAA domain AAA_5 PF07728.14 RLN63252.1 - 1.8e-13 50.7 3.2 0.037 14.0 0.0 4.9 4 0 0 4 4 4 4 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 RLN63252.1 - 1.2e-12 48.0 0.7 0.26 11.0 0.0 5.7 5 0 0 5 5 5 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 RLN63252.1 - 4.3e-11 42.9 17.5 0.0079 15.9 0.6 6.1 6 0 0 6 6 5 4 AAA domain Mg_chelatase PF01078.21 RLN63252.1 - 5e-11 42.4 5.5 0.12 11.8 0.1 6.7 4 3 3 7 7 7 3 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 RLN63252.1 - 1.3e-10 41.9 6.4 0.073 13.6 0.0 5.4 5 0 0 5 5 4 3 AAA domain AAA_19 PF13245.6 RLN63252.1 - 1.7e-10 41.4 3.4 1.2 9.4 0.0 6.8 5 1 1 6 6 6 2 AAA domain AAA_11 PF13086.6 RLN63252.1 - 2.2e-10 40.8 23.6 1e-06 28.8 0.0 6.8 7 0 0 7 7 6 1 AAA domain AAA_16 PF13191.6 RLN63252.1 - 1.3e-09 38.7 11.9 0.072 13.5 0.0 5.9 4 1 0 5 5 5 3 AAA ATPase domain AAA_33 PF13671.6 RLN63252.1 - 8.1e-09 35.8 4.3 0.33 11.1 0.1 4.8 4 0 0 4 4 4 2 AAA domain RNA_helicase PF00910.22 RLN63252.1 - 4.3e-08 33.5 0.4 3.3 8.2 0.0 4.8 4 0 0 4 4 4 1 RNA helicase AAA_2 PF07724.14 RLN63252.1 - 3.7e-07 30.4 0.1 0.21 11.7 0.0 4.4 4 0 0 4 4 4 2 AAA domain (Cdc48 subfamily) MCM PF00493.23 RLN63252.1 - 1e-05 24.8 2.0 0.012 14.8 0.0 4.0 4 0 0 4 4 4 1 MCM P-loop domain AAA_24 PF13479.6 RLN63252.1 - 1e-05 25.3 0.5 5.4 6.7 0.0 5.0 4 0 0 4 4 4 0 AAA domain TniB PF05621.11 RLN63252.1 - 2.3e-05 23.9 1.1 3.4 7.0 0.1 5.4 6 1 1 7 7 5 1 Bacterial TniB protein AAA_3 PF07726.11 RLN63252.1 - 5.2e-05 23.1 0.4 6.3 6.7 0.0 4.5 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 RLN63252.1 - 0.00012 22.0 1.5 12 6.0 0.0 4.4 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Torsin PF06309.11 RLN63252.1 - 0.00016 21.8 0.2 7.2 6.7 0.0 3.8 3 0 0 3 3 3 0 Torsin AAA_7 PF12775.7 RLN63252.1 - 0.00025 20.6 4.7 1.8 8.0 0.1 4.4 4 0 0 4 4 4 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 RLN63252.1 - 0.00075 19.3 1.9 13 5.5 0.0 4.4 4 0 0 4 4 4 0 IstB-like ATP binding protein ABC_tran PF00005.27 RLN63252.1 - 0.00088 19.8 9.6 9.7 6.7 0.0 5.5 5 0 0 5 5 4 0 ABC transporter NACHT PF05729.12 RLN63252.1 - 0.0018 18.2 1.7 5.2 7.0 0.0 4.4 4 0 0 4 4 4 0 NACHT domain NTPase_1 PF03266.15 RLN63252.1 - 0.002 18.0 6.9 10 6.0 0.1 4.5 4 0 0 4 4 4 0 NTPase APS_kinase PF01583.20 RLN63252.1 - 0.003 17.5 1.8 11 5.9 0.0 3.8 4 0 0 4 4 3 0 Adenylylsulphate kinase AAA_28 PF13521.6 RLN63252.1 - 0.0063 16.8 18.0 2.1 8.6 0.0 5.7 6 1 0 6 6 4 2 AAA domain Thymidylate_kin PF02223.17 RLN63252.1 - 0.011 15.5 1.4 28 4.3 0.1 4.1 3 0 0 3 3 3 0 Thymidylate kinase Parvo_NS1 PF01057.17 RLN63252.1 - 0.022 13.8 0.8 7.1 5.6 0.0 3.5 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 CbiA PF01656.23 RLN63252.1 - 0.027 14.5 6.0 5.8 7.0 0.1 4.4 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.9 RLN63252.1 - 0.032 13.5 13.0 21 4.2 0.1 5.8 5 1 0 5 5 5 0 Uncharacterized conserved protein (DUF2075) CPSase_sm_chain PF00988.22 RLN63252.1 - 0.061 13.1 0.3 18 5.1 0.1 3.2 3 0 0 3 3 2 0 Carbamoyl-phosphate synthase small chain, CPSase domain PRK PF00485.18 RLN63252.1 - 0.068 12.9 6.0 9 6.0 0.0 4.0 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family UvrD_C_2 PF13538.6 RLN63252.1 - 0.081 12.8 0.0 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain TrwB_AAD_bind PF10412.9 RLN63252.1 - 0.091 11.6 4.6 2.8 6.8 0.2 3.8 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain DnaJ-X PF14308.6 RLN63252.1 - 0.13 11.7 0.0 0.13 11.7 0.0 3.1 3 0 0 3 3 3 0 X-domain of DnaJ-containing Transposase_20 PF02371.16 RLN63252.1 - 0.15 12.4 0.2 16 5.9 0.0 3.5 4 0 0 4 4 3 0 Transposase IS116/IS110/IS902 family KTI12 PF08433.10 RLN63252.1 - 0.15 11.5 8.2 15 5.0 0.1 4.7 5 0 0 5 5 5 0 Chromatin associated protein KTI12 PhoH PF02562.16 RLN63252.1 - 0.34 10.3 11.1 4.1 6.8 0.5 4.6 4 0 0 4 4 4 0 PhoH-like protein DUF3987 PF13148.6 RLN63252.1 - 0.51 9.3 0.0 0.51 9.3 0.0 5.9 7 0 0 7 7 5 0 Protein of unknown function (DUF3987) zf-TRM13_CCCH PF11722.8 RLN63252.1 - 0.56 10.0 7.7 0.19 11.5 0.2 3.7 3 0 0 3 3 2 0 CCCH zinc finger in TRM13 protein ResIII PF04851.15 RLN63252.1 - 1.2 9.2 12.6 1 9.3 0.0 5.5 5 3 1 7 7 4 0 Type III restriction enzyme, res subunit Mur_ligase_M PF08245.12 RLN63252.1 - 1.5 8.8 12.1 12 5.9 0.4 4.1 4 0 0 4 4 4 0 Mur ligase middle domain SKI PF01202.22 RLN63252.1 - 1.7 8.8 10.6 17 5.5 0.1 4.4 4 0 0 4 4 3 0 Shikimate kinase PTPlike_phytase PF14566.6 RLN63252.1 - 2.2 8.4 5.8 58 3.8 0.0 4.0 3 0 0 3 3 3 0 Inositol hexakisphosphate TPR_12 PF13424.6 RLN63253.1 - 1.2e-06 28.6 0.9 0.075 13.3 0.2 4.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN63253.1 - 9.7e-05 22.1 1.5 1.1 9.4 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN63253.1 - 0.00011 21.9 4.7 1.5 8.8 0.2 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 RLN63253.1 - 0.00018 21.4 2.7 5.2 7.4 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN63253.1 - 0.00023 21.6 0.1 0.028 14.9 0.1 2.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN63253.1 - 0.00026 21.6 0.1 1.5 9.5 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN63253.1 - 0.00053 20.6 0.7 5 8.2 0.0 4.0 2 1 2 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN63253.1 - 0.002 18.3 1.1 0.15 12.3 0.3 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 RLN63253.1 - 0.0087 16.2 1.2 11 6.5 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF3808 PF10300.9 RLN63253.1 - 0.011 14.5 1.5 0.088 11.5 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3808) TPR_MalT PF17874.1 RLN63253.1 - 0.019 14.4 0.2 0.028 13.8 0.2 1.3 1 0 0 1 1 1 0 MalT-like TPR region SNAP PF14938.6 RLN63253.1 - 0.033 13.6 4.2 0.035 13.5 1.5 2.0 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP MIT PF04212.18 RLN63253.1 - 0.035 14.2 3.6 0.46 10.6 0.1 2.6 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain Rubrerythrin PF02915.17 RLN63253.1 - 0.043 14.2 3.0 0.079 13.4 1.7 2.1 1 1 1 2 2 2 0 Rubrerythrin TPR_6 PF13174.6 RLN63253.1 - 0.067 13.9 1.6 3.6 8.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 RLN63253.1 - 8.1 6.2 5.9 10 5.9 0.3 3.3 4 0 0 4 4 4 0 TPR repeat Phage_GPO PF05929.11 RLN63277.1 - 0.019 14.6 0.6 0.027 14.1 0.6 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase BROMI PF14961.6 RLN63277.1 - 0.036 11.5 0.3 0.047 11.1 0.3 1.1 1 0 0 1 1 1 0 Broad-minded protein LOH1CR12 PF10158.9 RLN63277.1 - 0.053 13.6 0.3 0.11 12.5 0.3 1.5 1 0 0 1 1 1 0 Tumour suppressor protein TOH_N PF12549.8 RLN63278.1 - 1.7 8.6 4.5 5 7.1 4.5 1.8 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal bZIP_1 PF00170.21 RLN63279.1 - 2.2e-05 24.5 4.9 2.2e-05 24.5 4.9 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 RLN63279.1 - 5.7e-05 23.1 5.1 5.7e-05 23.1 5.1 2.2 2 0 0 2 2 2 1 Basic region leucine zipper RAP1 PF07218.11 RLN63279.1 - 0.045 12.1 3.8 0.06 11.6 3.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4407 PF14362.6 RLN63279.1 - 0.17 11.2 4.0 0.24 10.7 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.9 RLN63279.1 - 0.35 9.4 7.2 0.48 8.9 7.2 1.1 1 0 0 1 1 1 0 Macoilin family bZIP_1 PF00170.21 RLN63280.1 - 0.00071 19.6 7.1 0.0016 18.5 7.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF2524 PF10732.9 RLN63280.1 - 0.078 13.3 3.6 0.18 12.1 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) Spc7 PF08317.11 RLN63280.1 - 0.75 8.6 7.0 1.2 8.0 7.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Metallophos PF00149.28 RLN63281.1 - 3.8e-09 37.3 0.3 1.7e-07 32.0 0.3 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RLN63281.1 - 0.18 12.0 6.2 1.2 9.3 6.2 2.2 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain ABC_tran_CTD PF16326.5 RLN63282.1 - 0.0055 16.9 3.0 0.0055 16.9 3.0 3.4 4 0 0 4 4 4 1 ABC transporter C-terminal domain DUF4140 PF13600.6 RLN63282.1 - 2.5 8.6 0.0 2.5 8.6 0.0 4.7 4 1 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) Golgin_A5 PF09787.9 RLN63282.1 - 4.2 6.8 19.7 0.22 10.9 13.6 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 Cep57_CLD PF14073.6 RLN63282.1 - 6.1 6.8 28.3 1.6 8.7 23.6 2.7 2 1 0 2 2 2 0 Centrosome localisation domain of Cep57 Cep57_MT_bd PF06657.13 RLN63283.1 - 0.0039 17.6 0.2 0.035 14.6 0.2 2.1 1 1 0 1 1 1 1 Centrosome microtubule-binding domain of Cep57 TolA_bind_tri PF16331.5 RLN63283.1 - 0.069 13.2 1.0 0.28 11.3 0.0 2.3 3 0 0 3 3 3 0 TolA binding protein trimerisation Herpes_DNAp_acc PF04929.12 RLN63284.1 - 0.057 12.4 2.9 0.085 11.8 2.9 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Antibiotic_NAT PF02522.14 RLN63285.1 - 0.023 14.5 0.1 2.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Aminoglycoside 3-N-acetyltransferase Prp19 PF08606.11 RLN63285.1 - 0.68 10.0 9.0 0.65 10.0 0.1 4.0 4 1 0 4 4 4 0 Prp19/Pso4-like zf-RING_6 PF14835.6 RLN63285.1 - 0.69 9.8 4.1 5.4 7.0 0.2 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Na_Pi_cotrans PF02690.15 RLN63286.1 - 1e-20 74.3 7.0 1.3e-20 73.9 7.0 1.1 1 0 0 1 1 1 1 Na+/Pi-cotransporter PEMT PF04191.13 RLN63286.1 - 0.12 12.8 3.2 0.083 13.3 1.1 1.8 1 1 1 2 2 2 0 Phospholipid methyltransferase Bac_export_1 PF01311.20 RLN63286.1 - 0.45 10.0 9.2 1.4 8.4 0.8 2.1 1 1 1 2 2 2 0 Bacterial export proteins, family 1 FAD_binding_2 PF00890.24 RLN63287.1 - 3.8e-72 243.7 0.3 3.8e-72 243.7 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain GMC_oxred_N PF00732.19 RLN63287.1 - 0.02 14.2 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase DAO PF01266.24 RLN63287.1 - 0.12 12.0 1.3 2.1 7.9 0.0 3.0 2 1 1 4 4 4 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RLN63287.1 - 0.22 11.8 0.9 8.8 6.6 0.0 3.4 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 RLN63287.1 - 0.32 10.2 1.8 66 2.6 0.0 3.6 4 0 0 4 4 4 0 Thi4 family Cation_ATPase_C PF00689.21 RLN63288.1 - 7.1e-50 169.2 0.6 7.1e-50 169.2 0.6 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 RLN63288.1 - 6.3e-30 104.0 1.3 3.3e-21 75.6 0.0 3.7 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase PF13246.6 RLN63288.1 - 1.9e-18 66.3 0.0 3.9e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RLN63288.1 - 1.3e-14 55.0 0.8 8.1e-14 52.4 0.8 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RLN63288.1 - 4.4e-12 45.5 0.0 1.1e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus ATP_Ca_trans_C PF12424.8 RLN63288.1 - 1.8e-07 31.5 1.0 4.4e-07 30.3 1.0 1.6 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Hydrolase_3 PF08282.12 RLN63288.1 - 1.1e-05 25.3 2.0 0.0006 19.6 1.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF962 PF06127.11 RLN63288.1 - 0.039 14.0 0.7 0.46 10.6 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF962) DUF1980 PF09323.10 RLN63288.1 - 0.3 11.0 1.6 2 8.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Sec63 PF02889.16 RLN63330.1 - 1.7e-148 492.8 0.0 4.1e-82 275.2 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 RLN63330.1 - 2.2e-13 50.4 0.0 6.3e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN63330.1 - 2.3e-13 50.4 0.0 1.3e-08 35.2 0.0 3.7 2 2 0 2 2 2 2 Helicase conserved C-terminal domain CRAL_TRIO PF00650.20 RLN63331.1 - 1.2e-09 38.0 0.0 2.2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Tau95_N PF17682.1 RLN63332.1 - 5.2e-22 78.4 1.1 2e-21 76.5 0.0 2.4 2 0 0 2 2 2 1 Tau95 Triple barrel domain Tau95 PF09734.9 RLN63332.1 - 1.1e-21 78.1 1.0 2.3e-21 77.1 0.0 2.1 3 0 0 3 3 3 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Myosin_head PF00063.21 RLN63360.1 - 5.8e-221 735.3 0.1 2e-220 733.6 0.1 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) IQ PF00612.27 RLN63360.1 - 0.0019 17.8 24.5 0.022 14.5 0.3 5.2 5 0 0 5 5 5 2 IQ calmodulin-binding motif AAA_22 PF13401.6 RLN63360.1 - 0.013 15.8 0.0 0.055 13.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RLN63360.1 - 0.03 13.6 0.0 0.06 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 RLN63360.1 - 0.031 14.7 0.0 0.11 12.8 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 RLN63360.1 - 0.043 14.3 0.1 0.12 12.9 0.1 1.8 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 RLN63360.1 - 0.065 13.8 0.1 0.24 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain RAP PF08373.10 RLN63360.1 - 2.6 8.2 6.8 2.3 8.4 0.3 3.0 3 1 0 3 3 3 0 RAP domain RAB3GAP2_C PF14656.6 RLN63451.1 - 0.048 11.9 0.1 0.066 11.4 0.1 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus RAB3GAP2_N PF14655.6 RLN63452.1 - 2e-53 182.1 0.0 3.7e-53 181.3 0.0 1.4 1 1 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus EphA2_TM PF14575.6 RLN63453.1 - 0.016 16.1 0.0 0.34 11.8 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TRM13 PF05206.14 RLN63453.1 - 0.036 13.6 0.1 0.054 13.0 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 DUF5305 PF17231.2 RLN63453.1 - 0.045 13.2 0.1 0.073 12.5 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) IQ PF00612.27 RLN63454.1 - 5.4e-16 56.8 52.9 0.00093 18.8 0.7 9.1 9 0 0 9 9 9 8 IQ calmodulin-binding motif zf-B_box PF00643.24 RLN63454.1 - 1.2e-06 28.6 18.3 0.0019 18.3 2.8 2.5 2 0 0 2 2 2 2 B-box zinc finger WW PF00397.26 RLN63454.1 - 6.4e-05 22.9 16.9 0.00014 21.8 4.7 2.6 2 0 0 2 2 2 2 WW domain CEBP_ZZ PF16366.5 RLN63454.1 - 0.025 14.8 21.1 0.75 10.1 8.4 2.5 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Elicitin PF00964.17 RLN63508.1 - 3.1e-21 75.3 0.5 3.8e-21 75.0 0.5 1.1 1 0 0 1 1 1 1 Elicitin FSH1 PF03959.13 RLN63509.1 - 1.4e-35 122.9 0.0 2e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF1184 PF06683.11 RLN63509.1 - 0.2 11.2 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) FSH1 PF03959.13 RLN63510.1 - 1.5e-33 116.2 0.0 2.1e-33 115.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Palm_thioest PF02089.15 RLN63510.1 - 0.1 12.4 0.0 0.27 11.1 0.0 1.4 1 1 0 1 1 1 0 Palmitoyl protein thioesterase FSH1 PF03959.13 RLN63511.1 - 1.9e-35 122.5 0.0 5.2e-35 121.0 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF2238 PF09997.9 RLN63511.1 - 0.054 13.3 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2238) FSH1 PF03959.13 RLN63512.1 - 4.8e-72 242.1 0.0 3e-37 128.3 0.0 2.5 2 1 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 RLN63512.1 - 0.019 14.8 0.0 5.1 6.8 0.0 2.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Methyltransf_24 PF13578.6 RLN63512.1 - 0.034 15.2 0.0 5.4 8.1 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain DUF2238 PF09997.9 RLN63512.1 - 0.038 13.8 0.1 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2238) PAP2 PF01569.21 RLN63512.1 - 0.074 12.8 0.7 3.6 7.4 0.0 2.6 2 0 0 2 2 2 0 PAP2 superfamily OpcA_G6PD_assem PF10128.9 RLN63512.1 - 0.14 11.7 0.0 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Glucose-6-phosphate dehydrogenase subunit FSH1 PF03959.13 RLN63513.1 - 7.7e-35 120.5 0.0 8.8e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 RLN63513.1 - 0.0049 16.7 0.0 0.0093 15.8 0.0 1.5 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Ion_trans PF00520.31 RLN63514.1 - 2.1e-46 158.2 8.0 6.7e-25 87.7 2.8 2.4 2 0 0 2 2 2 2 Ion transport protein cNMP_binding PF00027.29 RLN63514.1 - 8.7e-32 109.1 0.1 3e-17 62.5 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 RLN63514.1 - 4.1e-18 65.1 9.4 1.5e-08 34.5 2.8 2.8 2 0 0 2 2 2 2 Ion channel ANAPC4_WD40 PF12894.7 RLN63514.1 - 0.17 12.2 0.0 0.52 10.7 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain polyprenyl_synt PF00348.17 RLN63601.1 - 4.4e-62 209.4 0.0 7.8e-62 208.6 0.0 1.4 2 0 0 2 2 2 1 Polyprenyl synthetase Laminin_G_3 PF13385.6 RLN63602.1 - 0.00013 22.2 0.0 0.00033 20.8 0.0 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily ubiquitin PF00240.23 RLN63603.1 - 2.4e-10 40.0 0.8 3.7e-06 26.6 0.0 3.5 4 0 0 4 4 4 2 Ubiquitin family Ubiquitin_2 PF14560.6 RLN63603.1 - 0.00016 22.1 0.0 0.36 11.3 0.0 3.2 2 1 1 3 3 3 2 Ubiquitin-like domain TBK1_ULD PF18396.1 RLN63603.1 - 0.00093 19.1 1.5 0.017 15.1 0.0 3.0 4 0 0 4 4 4 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 RLN63603.1 - 0.047 14.0 0.1 0.5 10.8 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Alpha-mann_mid PF09261.11 RLN63603.1 - 0.09 12.9 1.8 0.19 11.9 1.1 2.0 1 1 1 2 2 2 0 Alpha mannosidase middle domain UN_NPL4 PF11543.8 RLN63603.1 - 0.091 13.3 0.1 29 5.2 0.0 3.2 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 Mrr_N PF14338.6 RLN63603.1 - 1.1 9.4 6.1 2.2 8.5 0.0 3.3 3 0 0 3 3 3 0 Mrr N-terminal domain MAT1 PF06391.13 RLN63603.1 - 1.8 8.3 5.8 0.67 9.7 2.1 2.0 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Transferase PF02458.15 RLN63604.1 - 3e-24 85.5 0.0 1e-23 83.8 0.0 1.8 1 1 0 1 1 1 1 Transferase family Tetraspanin PF00335.20 RLN63604.1 - 0.0041 16.9 2.6 0.0059 16.3 2.6 1.2 1 0 0 1 1 1 1 Tetraspanin family Transferase PF02458.15 RLN63605.1 - 1.9e-32 112.5 0.0 5.5e-32 111.0 0.0 1.6 1 1 0 1 1 1 1 Transferase family Metallophos PF00149.28 RLN63607.1 - 2.3e-10 41.4 0.0 4.8e-10 40.3 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RLN63607.1 - 0.013 15.7 0.0 0.21 11.8 0.0 2.2 1 1 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain SpoIIIAH PF12685.7 RLN63607.1 - 0.15 11.9 0.1 0.23 11.3 0.1 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Pro_isomerase PF00160.21 RLN63608.1 - 3.3e-51 173.7 0.1 6.8e-51 172.7 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 RLN63608.1 - 1.5e-14 54.1 0.1 0.00022 22.0 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN63608.1 - 1.2e-05 25.5 0.0 0.71 10.2 0.0 4.0 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN63608.1 - 0.00045 19.3 0.1 0.61 9.0 0.0 3.0 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Transp_cyt_pur PF02133.15 RLN63609.1 - 3.7e-44 151.2 35.2 4.5e-44 150.9 35.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin bPH_5 PF10882.8 RLN63609.1 - 0.099 12.7 0.3 0.36 10.9 0.1 2.0 2 0 0 2 2 2 0 Bacterial PH domain LRR_4 PF12799.7 RLN63610.1 - 1.1e-08 35.2 16.3 0.0015 18.9 0.6 8.4 5 2 5 11 11 11 5 Leucine Rich repeats (2 copies) Peptidase_C1 PF00112.23 RLN63611.1 - 2.3e-69 233.8 6.0 3.3e-69 233.3 6.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 RLN63611.1 - 8.8e-14 51.7 0.6 1.5e-13 51.0 0.6 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 RLN63611.1 - 6e-07 28.6 2.1 0.00061 18.7 0.5 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Nucleo_LEF-12 PF06256.11 RLN63611.1 - 0.24 11.1 0.1 0.24 11.1 0.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus LEF-12 protein PSI PF01437.25 RLN63611.1 - 9.7 6.8 15.3 0.66 10.6 7.8 2.5 2 0 0 2 2 2 0 Plexin repeat Cation_efflux PF01545.21 RLN63612.1 - 1.2e-46 159.0 1.4 1.4e-46 158.7 1.4 1.0 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.22 RLN63612.1 - 0.019 14.2 13.6 0.027 13.7 12.9 1.6 1 1 0 1 1 1 0 ZIP Zinc transporter Ctr PF04145.15 RLN63612.1 - 0.11 13.1 0.5 0.62 10.7 0.0 2.4 3 1 0 3 3 3 0 Ctr copper transporter family DUF1282 PF06930.12 RLN63612.1 - 0.69 9.7 5.1 1.4 8.6 4.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) DDE_Tnp_ISL3 PF01610.17 RLN63613.1 - 0.78 9.4 6.5 1.1 8.9 6.5 1.1 1 0 0 1 1 1 0 Transposase MFS_1 PF07690.16 RLN63664.1 - 6.4e-08 31.9 0.0 6.6e-08 31.9 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN63664.1 - 0.0037 16.2 0.0 0.0039 16.1 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DEK_C PF08766.11 RLN63665.1 - 8.3e-09 35.2 0.2 2.3e-08 33.8 0.2 1.8 1 0 0 1 1 1 1 DEK C terminal domain PWWP PF00855.17 RLN63665.1 - 3.5e-05 24.1 0.0 3.5e-05 24.1 0.0 3.7 2 1 0 2 2 2 1 PWWP domain YL1 PF05764.13 RLN63665.1 - 0.00029 21.1 30.3 0.00029 21.1 30.3 2.0 2 0 0 2 2 2 1 YL1 nuclear protein Med26 PF08711.11 RLN63665.1 - 0.31 11.1 9.3 0.57 10.3 0.2 3.4 4 0 0 4 4 4 0 TFIIS helical bundle-like domain LTV PF04180.14 RLN63665.1 - 2.7 7.6 30.6 4.5 6.9 2.2 2.3 2 0 0 2 2 2 0 Low temperature viability protein DUF572 PF04502.13 RLN63665.1 - 4.3 6.9 28.7 0.36 10.4 21.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) NPR3 PF03666.13 RLN63665.1 - 5.4 5.7 22.3 11 4.6 22.3 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CCSAP PF15748.5 RLN63665.1 - 7.9 6.6 26.8 2.5 8.2 21.9 2.0 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated PPP1R35_C PF15503.6 RLN63666.1 - 1.8 8.4 9.8 0.21 11.4 5.1 1.8 2 0 0 2 2 2 0 Protein phosphatase 1 regulatory subunit 35 C-terminus Pescadillo_N PF06732.11 RLN63667.1 - 5.2e-114 380.4 0.9 5.2e-114 380.4 0.9 2.3 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 RLN63667.1 - 1.5e-09 38.1 0.0 2.5e-08 34.2 0.0 2.5 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Peptidase_M24 PF00557.24 RLN63668.1 - 8.8e-21 74.5 0.0 1.1e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 TTL PF03133.15 RLN63670.1 - 2.2e-70 237.1 0.0 2.6e-51 174.5 0.0 2.4 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RLN63670.1 - 1.8e-07 30.7 0.1 1.6e-05 24.3 0.0 2.8 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RLN63670.1 - 0.012 14.9 0.0 0.095 11.9 0.0 2.2 2 1 1 3 3 3 0 Sugar-transfer associated ATP-grasp FH2 PF02181.23 RLN63773.1 - 3.7e-69 233.6 1.8 5.9e-69 233.0 1.8 1.3 1 0 0 1 1 1 1 Formin Homology 2 Domain CCDC53 PF10152.9 RLN63773.1 - 4.6e-34 118.0 42.3 1.8e-13 51.1 15.3 6.4 5 2 0 5 5 5 3 Subunit CCDC53 of WASH complex YebG PF07130.12 RLN63773.1 - 0.11 12.4 0.7 1.5 8.7 0.0 3.0 3 0 0 3 3 3 0 YebG protein CytadhesinP1 PF12378.8 RLN63774.1 - 0.18 11.9 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Trypsin-sensitive surface-exposed protein HemY_N PF07219.13 RLN63774.1 - 0.28 11.4 0.1 0.28 11.4 0.1 2.3 2 0 0 2 2 2 0 HemY protein N-terminus UPF0029 PF01205.19 RLN63776.1 - 6.4e-08 32.9 0.0 1.5e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 Acetyltransf_1 PF00583.25 RLN63777.1 - 2.2e-12 47.3 0.0 2.9e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RLN63777.1 - 6.2e-06 26.2 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN63777.1 - 1.2e-05 25.1 0.0 2.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 RLN63777.1 - 0.00098 19.5 0.0 0.0016 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 RLN63777.1 - 0.015 15.4 0.1 0.024 14.7 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 RLN63777.1 - 0.073 13.2 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3882 PF07066.11 RLN63777.1 - 0.14 12.3 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Lactococcus phage M3 protein LMBR1 PF04791.16 RLN63779.1 - 2e-45 155.7 30.2 1.8e-28 99.8 7.7 2.0 1 1 1 2 2 2 2 LMBR1-like membrane protein Orf78 PF06024.12 RLN63779.1 - 0.029 14.7 5.9 0.64 10.4 0.1 3.1 2 0 0 2 2 2 0 Orf78 (ac78) Inhibitor_I53 PF11714.8 RLN63779.1 - 0.24 11.6 1.4 1.5 9.1 0.0 2.9 4 0 0 4 4 4 0 Thrombin inhibitor Madanin Viral_Beta_CD PF04530.12 RLN63779.1 - 0.61 10.4 5.1 11 6.4 1.9 2.7 2 0 0 2 2 2 0 Viral Beta C/D like family Baculo_VP91_N PF08475.10 RLN63779.1 - 7.5 6.2 6.6 27 4.4 0.1 2.3 2 0 0 2 2 2 0 Viral capsid protein 91 N-terminal Baculo_11_kDa PF06143.11 RLN63779.1 - 9.3 5.9 6.9 14 5.3 0.0 2.9 3 0 0 3 3 3 0 Baculovirus 11 kDa family AWS PF17907.1 RLN63810.1 - 1.4e-06 28.2 3.2 1.4e-06 28.2 3.2 2.3 2 0 0 2 2 2 1 AWS domain SET PF00856.28 RLN63810.1 - 0.00027 21.4 0.0 0.0032 17.9 0.1 2.2 2 0 0 2 2 2 1 SET domain TauE PF01925.19 RLN63811.1 - 3.4e-25 89.1 41.5 7.8e-14 51.9 14.9 2.7 2 1 0 2 2 2 2 Sulfite exporter TauE/SafE SOR_SNZ PF01680.17 RLN63812.1 - 2.1e-110 367.3 13.7 2.6e-110 367.1 11.2 1.9 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.14 RLN63812.1 - 2.4e-08 33.6 10.4 4e-08 32.9 1.1 2.7 2 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 RLN63812.1 - 0.0002 20.6 3.0 0.063 12.4 0.0 2.5 3 0 0 3 3 3 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 RLN63812.1 - 0.0022 17.5 1.6 0.039 13.4 0.1 2.3 2 0 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.21 RLN63812.1 - 0.0063 15.7 0.3 0.28 10.3 0.0 2.5 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase TetR_C_27 PF17935.1 RLN63812.1 - 0.0069 16.4 0.0 0.02 14.9 0.0 1.8 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain IMPDH PF00478.25 RLN63812.1 - 0.008 15.2 2.5 0.011 14.8 2.5 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain OMPdecase PF00215.24 RLN63812.1 - 0.022 14.4 2.7 1.6 8.2 0.0 2.5 2 1 1 3 3 3 0 Orotidine 5'-phosphate decarboxylase / HUMPS family NanE PF04131.14 RLN63812.1 - 0.024 13.8 3.9 0.037 13.2 0.1 2.7 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Fapy_DNA_glyco PF01149.24 RLN63812.1 - 0.037 14.7 0.1 0.19 12.4 0.0 2.0 2 0 0 2 2 2 0 Formamidopyrimidine-DNA glycosylase N-terminal domain NMO PF03060.15 RLN63812.1 - 0.12 11.8 8.7 0.062 12.7 0.7 2.4 2 0 0 2 2 2 0 Nitronate monooxygenase SYF2 PF08231.12 RLN63813.1 - 6.5e-26 91.6 7.8 6.5e-26 91.6 7.8 1.6 1 1 0 1 1 1 1 SYF2 splicing factor betaPIX_CC PF16523.5 RLN63813.1 - 0.011 15.6 0.3 0.011 15.6 0.3 2.0 2 0 0 2 2 2 0 betaPIX coiled coil TPR_2 PF07719.17 RLN63814.1 - 2.9e-18 64.4 0.7 0.00087 19.2 0.0 6.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 RLN63814.1 - 1.5e-17 63.9 0.0 4.2e-08 33.7 0.0 6.1 5 1 2 7 7 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN63814.1 - 2.6e-13 49.2 0.0 0.011 15.6 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 RLN63814.1 - 3.7e-10 39.9 0.4 0.01 16.1 0.0 5.5 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN63814.1 - 6e-10 38.6 0.0 0.12 12.7 0.0 5.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN63814.1 - 1.5e-08 34.0 0.7 0.11 12.6 0.0 6.2 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN63814.1 - 9.5e-08 32.4 0.0 0.00085 19.8 0.0 6.2 6 1 2 8 8 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN63814.1 - 3.6e-07 29.8 0.0 0.043 13.5 0.0 4.4 2 1 2 4 4 4 2 TPR repeat TPR_14 PF13428.6 RLN63814.1 - 3.6e-07 30.4 29.3 0.0036 18.0 0.0 8.5 8 2 2 10 10 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 RLN63814.1 - 3e-05 24.1 8.0 0.042 14.0 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN63814.1 - 3.9e-05 23.4 0.0 3.1 7.8 0.0 4.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN63814.1 - 0.00011 22.3 0.0 0.028 14.8 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN63814.1 - 0.026 15.1 7.6 14 6.6 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat RPN7 PF10602.9 RLN63814.1 - 0.04 13.6 0.0 0.81 9.4 0.0 2.9 3 0 0 3 3 3 0 26S proteasome subunit RPN7 ZapB PF06005.12 RLN63862.1 - 0.00055 20.3 1.7 0.3 11.6 0.0 2.4 2 0 0 2 2 2 2 Cell division protein ZapB Bap31_Bap29_C PF18035.1 RLN63862.1 - 0.021 14.8 0.4 0.021 14.8 0.4 1.8 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain CC2-LZ PF16516.5 RLN63862.1 - 0.027 14.8 0.4 0.35 11.3 0.0 2.3 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Mito_fiss_reg PF05308.11 RLN63862.1 - 0.037 14.1 0.8 0.051 13.7 0.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Spectrin_like PF18373.1 RLN63862.1 - 0.044 13.9 2.2 0.06 13.4 1.2 1.8 2 0 0 2 2 2 0 Spectrin like domain DASH_Spc34 PF08657.10 RLN63862.1 - 0.075 12.8 0.4 0.11 12.3 0.4 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 CCDC144C PF14915.6 RLN63862.1 - 0.29 10.2 3.8 0.45 9.6 3.8 1.3 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region CFAP91 PF14738.6 RLN63892.1 - 5.7e-52 175.8 5.9 5.7e-52 175.8 5.9 2.2 2 0 0 2 2 2 1 Cilia- and flagella-associated protein 91 Amino_oxidase PF01593.24 RLN63893.1 - 2.6e-27 96.2 0.0 3e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FYVE_2 PF02318.16 RLN63906.1 - 0.00018 21.7 5.1 0.00049 20.3 5.1 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 RLN63906.1 - 0.0054 16.8 10.5 0.011 15.8 10.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger Cytochrome_P460 PF16694.5 RLN63906.1 - 0.11 12.8 0.1 19 5.6 0.1 2.8 2 0 0 2 2 2 0 Cytochrome P460 DUF508 PF04370.12 RLN63906.1 - 3.2 7.5 6.9 0.8 9.4 2.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF508) FYVE_2 PF02318.16 RLN63907.1 - 0.017 15.3 9.5 0.048 13.9 9.5 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger Retinal PF15449.6 RLN63907.1 - 0.041 11.7 1.4 0.076 10.8 1.4 1.3 1 0 0 1 1 1 0 Retinal protein E1_UFD PF09358.10 RLN63943.1 - 1.7e-31 108.7 0.2 2.8e-31 108.1 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin fold domain UBA_e1_thiolCys PF10585.9 RLN63943.1 - 8.4e-12 45.5 0.9 2.1e-11 44.2 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site ThiF PF00899.21 RLN63943.1 - 4.2e-08 32.9 0.0 5.8e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family TUG-UBL1 PF11470.8 RLN63944.1 - 4e-16 59.0 0.0 6.4e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 TUG ubiquitin-like domain SET PF00856.28 RLN63945.1 - 6.2e-18 65.7 0.1 6.2e-18 65.7 0.1 3.1 3 2 0 3 3 3 1 SET domain PHD PF00628.29 RLN63945.1 - 1.1e-16 60.4 31.3 1.5e-09 37.6 3.8 4.4 4 0 0 4 4 4 3 PHD-finger PHD_2 PF13831.6 RLN63945.1 - 8.8e-05 22.0 1.7 8.8e-05 22.0 1.7 3.9 4 0 0 4 4 4 1 PHD-finger AWS PF17907.1 RLN63945.1 - 9.1e-05 22.4 3.9 0.0032 17.5 0.1 3.4 2 0 0 2 2 2 1 AWS domain zf-HC5HC2H PF13771.6 RLN63945.1 - 0.089 13.1 34.1 0.026 14.8 7.6 4.5 2 1 2 4 4 4 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 RLN63945.1 - 2.9 8.1 35.5 0.025 14.7 6.1 4.3 3 1 2 5 5 5 0 PHD-zinc-finger like domain PUB PF09409.10 RLN63946.1 - 9.3e-19 67.2 0.0 1.9e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 PUB domain UBX PF00789.20 RLN63946.1 - 0.0011 19.2 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain Pkinase PF00069.25 RLN63947.1 - 9.5e-27 94.0 0.0 9.4e-25 87.5 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN63947.1 - 1.2e-25 90.2 0.0 6.4e-24 84.6 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN63947.1 - 0.034 12.9 0.2 0.11 11.3 0.2 1.8 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 RLN63947.1 - 0.043 13.4 0.0 0.097 12.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family CENP-B_dimeris PF09026.10 RLN63947.1 - 0.051 14.0 9.5 0.14 12.5 9.5 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain APH PF01636.23 RLN63947.1 - 0.08 12.8 0.5 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family FAM176 PF14851.6 RLN63947.1 - 0.16 11.7 1.9 0.39 10.4 1.9 1.7 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 RLN63947.1 - 0.18 11.8 2.5 0.39 10.7 2.5 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 RLN63947.1 - 4.6 6.5 7.9 7.6 5.7 7.9 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 RLN63947.1 - 5.7 6.0 11.6 1.9 7.6 8.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Pes-10 PF07149.11 RLN63947.1 - 8 5.4 10.0 8.1 5.4 8.3 1.7 2 0 0 2 2 2 0 Pes-10 Pox_A14 PF05767.12 RLN63948.1 - 1.7 8.8 5.2 4.2 7.6 1.2 2.4 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 UL73_N PF12522.8 RLN63948.1 - 7.9 6.3 7.5 0.44 10.3 1.3 2.3 2 0 0 2 2 2 0 Cytomegalovirus glycoprotein N terminal Cyt-b5 PF00173.28 RLN63958.1 - 4e-15 55.7 0.1 5.7e-15 55.2 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Snapin_Pallidin PF14712.6 RLN63959.1 - 3.6e-16 59.4 5.7 7e-16 58.4 5.7 1.5 1 0 0 1 1 1 1 Snapin/Pallidin Pribosyl_synth PF14572.6 RLN63959.1 - 0.017 15.2 0.6 0.038 14.0 0.6 1.6 1 1 0 1 1 1 0 Phosphoribosyl synthetase-associated domain Med21 PF11221.8 RLN63959.1 - 0.065 13.5 0.1 0.065 13.5 0.1 3.8 3 2 1 4 4 4 0 Subunit 21 of Mediator complex YabA PF06156.13 RLN63959.1 - 2.7 8.7 5.0 3.6 8.3 2.4 2.4 1 1 1 2 2 2 0 Initiation control protein YabA CxC6 PF18721.1 RLN64002.1 - 0.00045 20.4 1.2 0.00045 20.4 1.2 4.2 1 1 2 4 4 4 1 CxC6 like cysteine cluster associated with KDZ transposases DUF3586 PF12131.8 RLN64002.1 - 0.0049 17.0 5.4 0.0049 17.0 5.4 3.6 1 1 2 4 4 4 1 Protein of unknown function (DUF3586) CxC6 PF18721.1 RLN64003.1 - 0.00045 20.4 1.3 0.00045 20.4 1.3 4.2 1 1 1 3 3 3 2 CxC6 like cysteine cluster associated with KDZ transposases DUF3586 PF12131.8 RLN64003.1 - 0.0043 17.2 5.0 0.0043 17.2 5.0 3.7 1 1 2 4 4 4 1 Protein of unknown function (DUF3586) Dynamitin PF04912.14 RLN64049.1 - 4.9e-43 147.9 5.0 5.7e-43 147.7 5.0 1.1 1 0 0 1 1 1 1 Dynamitin CLZ PF16526.5 RLN64049.1 - 2.1e-05 24.8 9.9 0.0061 16.9 0.3 4.7 3 2 1 4 4 4 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1073 PF06381.11 RLN64049.1 - 0.014 14.2 1.8 0.029 13.2 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1073) DUF2730 PF10805.8 RLN64049.1 - 0.19 11.9 3.0 19 5.4 0.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) DUF1664 PF07889.12 RLN64049.1 - 0.52 10.3 4.4 13 5.9 0.5 3.6 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) TRAF_BIRC3_bd PF16673.5 RLN64049.1 - 0.89 9.4 3.3 16 5.4 0.0 3.4 4 0 0 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain SlyX PF04102.12 RLN64049.1 - 1.4 9.6 8.1 12 6.6 0.0 4.8 4 1 1 5 5 5 0 SlyX bZIP_1 PF00170.21 RLN64049.1 - 2 8.6 4.4 6.7 6.9 0.1 3.4 4 0 0 4 4 3 0 bZIP transcription factor KxDL PF10241.9 RLN64049.1 - 4 7.8 7.5 5.9 7.2 0.8 3.7 4 0 0 4 4 4 0 Uncharacterized conserved protein Phasin_2 PF09361.10 RLN64049.1 - 6 7.2 17.4 2.3 8.5 2.8 3.3 3 0 0 3 3 3 0 Phasin protein FliJ PF02050.16 RLN64049.1 - 9.4 6.5 9.1 0.55 10.5 0.6 3.0 4 1 0 4 4 4 0 Flagellar FliJ protein TRP PF06011.12 RLN64050.1 - 1.1e-21 77.0 14.1 6.3e-21 74.6 2.2 2.1 2 0 0 2 2 2 2 Transient receptor potential (TRP) ion channel Myb_DNA-binding PF00249.31 RLN64128.1 - 2.2e-15 56.6 0.3 4.8e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN64128.1 - 0.00019 21.6 0.0 0.05 13.9 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN64128.1 - 0.2 11.5 0.3 3.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Myb DNA-binding like fn3 PF00041.21 RLN64129.1 - 5.8e-10 39.4 0.1 0.00024 21.4 0.0 4.2 2 2 0 2 2 2 2 Fibronectin type III domain PA PF02225.22 RLN64129.1 - 1.2e-05 25.2 0.0 2.7e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 PA domain Pur_ac_phosph_N PF16656.5 RLN64129.1 - 0.0031 18.0 0.0 0.78 10.4 0.0 2.4 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain DUF1223 PF06764.11 RLN64129.1 - 0.025 14.6 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) DUF572 PF04502.13 RLN64130.1 - 2.5 7.6 19.5 3.6 7.1 19.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SUIM_assoc PF16619.5 RLN64131.1 - 0.024 14.7 5.0 0.11 12.6 0.5 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Kinesin PF00225.23 RLN64238.1 - 5.7e-77 258.9 0.3 5.7e-77 258.9 0.3 1.9 2 0 0 2 2 2 1 Kinesin motor domain TMF_DNA_bd PF12329.8 RLN64238.1 - 0.0053 16.7 1.5 0.0053 16.7 1.5 2.9 2 1 1 3 3 3 1 TATA element modulatory factor 1 DNA binding YabA PF06156.13 RLN64238.1 - 0.012 16.2 1.4 0.012 16.2 1.4 2.7 3 0 0 3 3 3 0 Initiation control protein YabA Microtub_bd PF16796.5 RLN64238.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Microtubule binding DivIC PF04977.15 RLN64238.1 - 0.12 12.1 14.5 0.12 12.2 1.9 2.6 2 0 0 2 2 2 0 Septum formation initiator DUF3450 PF11932.8 RLN64238.1 - 0.25 10.6 16.2 0.033 13.5 4.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) GED PF02212.18 RLN64238.1 - 1.6 8.9 9.4 0.14 12.3 1.5 2.6 2 0 0 2 2 2 0 Dynamin GTPase effector domain THOC7 PF05615.13 RLN64238.1 - 2 8.7 12.3 1.7 8.9 1.8 2.7 3 0 0 3 3 3 0 Tho complex subunit 7 APG6_N PF17675.1 RLN64238.1 - 4.6 7.8 17.9 4.1 7.9 4.2 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region Exo_endo_phos PF03372.23 RLN64239.1 - 1.6e-12 47.5 0.1 2.5e-12 46.8 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MazG-like PF12643.7 RLN64307.1 - 3.2e-09 36.9 0.1 2.4e-08 34.1 0.1 2.2 1 1 0 1 1 1 1 MazG-like family MazG PF03819.17 RLN64307.1 - 2.6e-05 24.3 0.0 7.7e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain FAR1 PF03101.15 RLN64307.1 - 0.11 13.2 0.3 0.18 12.5 0.3 1.3 1 0 0 1 1 1 0 FAR1 DNA-binding domain EIF_2_alpha PF07541.12 RLN64308.1 - 1.1e-41 141.6 0.2 1.1e-41 141.6 0.2 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit Ank_2 PF12796.7 RLN64322.1 - 8.3e-23 80.8 0.4 1.6e-09 38.2 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN64322.1 - 4.7e-16 58.9 1.7 0.0023 18.5 0.1 5.6 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN64322.1 - 1.5e-10 41.1 4.8 0.088 13.2 0.0 7.3 4 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN64322.1 - 1.6e-09 37.2 0.6 0.25 12.0 0.0 7.2 8 0 0 8 8 8 2 Ankyrin repeat Ank PF00023.30 RLN64322.1 - 1.5e-05 25.2 1.2 1.2 9.7 0.0 5.1 3 3 1 4 4 4 2 Ankyrin repeat SecA_DEAD PF07517.14 RLN64362.1 - 4.6e-25 88.5 0.0 7.9e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_PP_bind PF01043.20 RLN64362.1 - 6e-05 23.7 0.0 0.00014 22.4 0.0 1.6 1 0 0 1 1 1 1 SecA preprotein cross-linking domain Apolipoprotein PF01442.18 RLN64362.1 - 1.5 8.7 4.7 0.54 10.1 1.5 1.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain VCH_CASS14 PF18315.1 RLN64366.1 - 0.12 12.5 0.2 0.4 10.8 0.1 2.0 2 1 0 2 2 2 0 Integron cassette protein VCH_CASS1 chain DUF4596 PF15363.6 RLN64367.1 - 5.9 7.2 6.8 1 9.7 2.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4596) Arm PF00514.23 RLN64368.1 - 5.2e-06 26.3 1.4 1.6 8.9 0.0 4.3 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN64368.1 - 0.0068 16.8 0.2 2.6 8.5 0.0 3.5 3 0 0 3 3 3 1 HEAT repeats Ntox1 PF15500.6 RLN64368.1 - 0.0091 16.3 0.1 0.03 14.7 0.1 1.9 1 0 0 1 1 1 1 Putative RNase-like toxin, toxin_1 HEAT_EZ PF13513.6 RLN64368.1 - 0.018 15.6 0.4 0.18 12.4 0.0 2.8 2 0 0 2 2 2 0 HEAT-like repeat DNA_repr_REX1B PF14966.6 RLN64369.1 - 4.1e-16 59.4 3.8 3.3e-15 56.5 1.9 2.8 2 1 0 2 2 2 1 DNA repair REX1-B DUF948 PF06103.11 RLN64369.1 - 0.1 12.9 0.7 0.25 11.6 0.3 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Se-cys_synth_N PF12390.8 RLN64369.1 - 0.28 11.4 3.4 15 5.9 0.1 3.2 3 0 0 3 3 3 0 Selenocysteine synthase N terminal Zip PF02535.22 RLN64549.1 - 1.1e-25 90.6 21.5 1.1e-24 87.3 21.5 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Inositol_P PF00459.25 RLN64551.1 - 5.3e-34 118.0 0.0 9.2e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family EcKinase PF02958.20 RLN64551.1 - 2.6e-16 59.8 0.0 9.5e-16 58.0 0.0 1.9 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 RLN64551.1 - 1.5e-08 33.9 0.1 2.6e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 RLN64551.1 - 0.00011 22.2 9.9 0.0012 18.8 9.9 2.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 RLN64551.1 - 0.0049 16.5 0.0 0.0078 15.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 RLN64551.1 - 0.03 13.7 0.0 0.065 12.6 0.0 1.5 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase PX PF00787.24 RLN64552.1 - 3.2e-08 33.5 0.0 4.4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 PX domain 4HBT PF03061.22 RLN64553.1 - 7.4e-17 61.5 0.1 2.6e-07 30.9 0.1 2.3 2 0 0 2 2 2 2 Thioesterase superfamily MaoC_dehydratas PF01575.19 RLN64553.1 - 0.05 13.2 0.0 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 MaoC like domain YiiD_C PF09500.10 RLN64553.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) FYVE PF01363.21 RLN64554.1 - 3.2e-07 30.4 3.5 6.9e-07 29.3 3.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger DUF169 PF02596.15 RLN64555.1 - 0.098 12.6 0.0 0.11 12.4 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised ArCR, COG2043 4HBT PF03061.22 RLN64556.1 - 2.4e-17 63.0 0.7 4.4e-08 33.3 0.0 2.7 3 0 0 3 3 3 2 Thioesterase superfamily MaoC_dehydratas PF01575.19 RLN64556.1 - 0.1 12.1 0.1 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 MaoC like domain IQ PF00612.27 RLN64557.1 - 4.1e-14 51.0 122.9 0.00019 20.9 0.7 16.7 17 2 1 18 18 18 9 IQ calmodulin-binding motif LRR_6 PF13516.6 RLN64557.1 - 4e-12 45.1 15.1 0.054 13.6 0.0 9.5 10 0 0 10 10 10 4 Leucine Rich repeat LRR_4 PF12799.7 RLN64557.1 - 9.8e-05 22.6 10.1 1.4 9.4 0.0 6.2 4 3 4 8 8 8 4 Leucine Rich repeats (2 copies) DUF1319 PF07028.11 RLN64557.1 - 0.13 12.5 0.2 0.43 10.8 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) PX PF00787.24 RLN64558.1 - 6.4e-06 26.1 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 PX domain MtrB_PioB PF11854.8 RLN64558.1 - 0.042 12.2 0.1 0.056 11.8 0.1 1.1 1 0 0 1 1 1 0 Putative outer membrane beta-barrel porin, MtrB/PioB Nuc_deoxyri_tr2 PF15891.5 RLN64562.1 - 2e-21 76.3 0.2 1.3e-09 38.3 0.0 2.4 2 0 0 2 2 2 2 Nucleoside 2-deoxyribosyltransferase like Tweety PF04906.13 RLN64563.1 - 5.1e-13 48.5 1.7 8.2e-13 47.8 1.7 1.2 1 0 0 1 1 1 1 Tweety Abhydrolase_1 PF00561.20 RLN64593.1 - 1.9e-06 27.7 0.1 7.9e-05 22.4 0.1 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 RLN64593.1 - 1.1e-05 25.5 1.9 2.4e-05 24.4 0.1 2.5 3 0 0 3 3 3 1 TAP-like protein TMEM154 PF15102.6 RLN64593.1 - 0.0013 18.7 1.2 0.0052 16.7 0.0 2.6 2 0 0 2 2 2 1 TMEM154 protein family Hydrolase_4 PF12146.8 RLN64593.1 - 0.013 14.7 0.0 0.32 10.2 0.0 2.4 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Rax2 PF12768.7 RLN64593.1 - 0.029 13.8 0.0 0.07 12.6 0.0 1.6 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Nitrate_red_gam PF02665.14 RLN64593.1 - 0.05 13.1 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Insulin_TMD PF17870.1 RLN64593.1 - 0.1 12.7 0.1 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment PhoPQ_related PF10142.9 RLN64593.1 - 0.12 11.1 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein RWP-RK PF02042.15 RLN64594.1 - 1.6e-19 69.6 0.2 3.7e-19 68.4 0.2 1.6 1 0 0 1 1 1 1 RWP-RK domain Cep57_CLD PF14073.6 RLN64595.1 - 2.7 8.0 13.1 11 6.0 0.4 2.8 2 2 0 2 2 2 0 Centrosome localisation domain of Cep57 KH_1 PF00013.29 RLN64627.1 - 1.3e-54 181.9 4.5 5e-09 35.9 0.1 7.6 7 0 0 7 7 7 7 KH domain KH_2 PF07650.17 RLN64627.1 - 1.7e-11 43.7 9.4 0.23 11.3 0.0 6.2 5 1 0 5 5 5 5 KH domain KH_4 PF13083.6 RLN64627.1 - 1.5e-10 40.8 2.4 0.23 11.4 0.0 5.8 5 0 0 5 5 5 3 KH domain KH_5 PF13184.6 RLN64627.1 - 3.9e-07 30.0 2.9 0.47 10.6 0.1 5.4 5 0 0 5 5 5 2 NusA-like KH domain KAsynt_C_assoc PF16197.5 RLN64627.1 - 0.031 14.7 0.6 0.65 10.5 0.1 3.4 4 0 0 4 4 4 0 Ketoacyl-synthetase C-terminal extension UPF0184 PF03670.13 RLN64627.1 - 0.15 12.5 2.6 10 6.6 0.0 4.3 5 0 0 5 5 5 0 Uncharacterised protein family (UPF0184) DASH_Spc19 PF08287.11 RLN64627.1 - 8 6.3 11.5 0.83 9.5 2.9 3.4 3 0 0 3 3 3 0 Spc19 Kinesin PF00225.23 RLN64629.1 - 1.1e-12 47.6 0.0 1.6e-11 43.7 0.0 2.8 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RLN64629.1 - 0.035 14.1 0.0 0.085 12.8 0.0 1.7 1 0 0 1 1 1 0 Microtubule binding Myb_DNA-binding PF00249.31 RLN64630.1 - 2e-08 34.3 0.1 2e-08 34.3 0.1 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN64630.1 - 0.0083 16.4 0.1 0.016 15.5 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SARAF PF06682.12 RLN64631.1 - 0.023 14.4 2.1 0.21 11.2 0.3 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Agenet PF05641.12 RLN64631.1 - 0.04 14.4 0.0 0.17 12.4 0.0 2.1 1 1 0 1 1 1 0 Agenet domain PET117 PF15786.5 RLN64631.1 - 0.36 11.1 4.9 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial Aldo_ket_red PF00248.21 RLN64632.1 - 7.5e-46 156.7 0.0 8.4e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_trans_1_4 PF13692.6 RLN64633.1 - 8.9e-08 32.6 0.0 4.3e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 RLN64633.1 - 2.6e-07 30.4 0.0 3.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 RLN64633.1 - 1.8e-06 28.1 0.2 3.5e-06 27.1 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 RLN64633.1 - 1.3e-05 25.7 4.5 1.3e-05 25.7 4.5 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 RLN64633.1 - 0.017 15.5 0.0 0.034 14.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 PH PF00169.29 RLN64635.1 - 2.8e-25 88.9 0.0 1.3e-09 38.4 0.0 6.1 6 0 0 6 6 6 5 PH domain PH_6 PF15406.6 RLN64635.1 - 9.6e-05 22.6 1.0 0.037 14.3 0.0 3.6 3 0 0 3 3 3 1 Pleckstrin homology domain PH_9 PF15410.6 RLN64635.1 - 0.0016 18.8 0.1 1.6 9.1 0.0 4.3 5 0 0 5 5 5 1 Pleckstrin homology domain PH_13 PF16652.5 RLN64635.1 - 0.0035 17.2 2.6 1.2 8.9 0.3 3.8 4 0 0 4 4 4 1 Pleckstrin homology domain AAA_23 PF13476.6 RLN64635.1 - 0.14 12.6 3.4 0.16 12.4 1.4 2.1 2 0 0 2 2 2 0 AAA domain SesA PF17107.5 RLN64635.1 - 7.7 6.7 7.1 1.7 8.9 2.3 2.2 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Hydrolase_4 PF12146.8 RLN64636.1 - 5.9e-13 48.6 0.0 1.1e-11 44.5 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN64636.1 - 1.4e-10 41.3 0.6 6.9e-08 32.4 0.2 2.4 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN64636.1 - 1.2e-05 26.0 0.0 2.4e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 RLN64636.1 - 0.0042 16.7 0.0 0.01 15.5 0.0 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF915 PF06028.11 RLN64636.1 - 0.018 14.4 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Ndr PF03096.14 RLN64636.1 - 0.029 13.1 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family Abhydro_lipase PF04083.16 RLN64636.1 - 0.044 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region TIP120 PF08623.10 RLN64776.1 - 0.015 15.1 2.1 0.031 14.1 2.1 1.6 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) FdhE PF04216.12 RLN64776.1 - 0.74 9.6 5.6 0.26 11.1 1.7 2.0 2 1 1 3 3 3 0 Protein involved in formate dehydrogenase formation MIP PF00230.20 RLN64813.1 - 4.3e-48 164.0 11.2 5.4e-48 163.7 11.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein ketoacyl-synt PF00109.26 RLN64813.1 - 0.039 13.5 0.1 0.1 12.2 0.1 1.6 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ABC_tran PF00005.27 RLN64814.1 - 8.4e-16 58.7 0.0 1.4e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 RLN64814.1 - 0.0002 21.8 0.0 0.00046 20.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RLN64814.1 - 0.0015 18.8 0.0 0.0031 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 RLN64814.1 - 0.0069 15.7 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin EPSP_synthase PF00275.20 RLN64814.1 - 0.037 12.7 0.0 0.05 12.3 0.0 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) AAA_29 PF13555.6 RLN64814.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN64814.1 - 0.061 13.2 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 RLN64814.1 - 0.074 12.8 0.0 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 RLN64814.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E AAA_7 PF12775.7 RLN64814.1 - 0.12 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 RLN64814.1 - 0.15 11.9 0.1 0.4 10.6 0.1 1.7 1 0 0 1 1 1 0 NACHT domain CDP-OH_P_transf PF01066.21 RLN64815.1 - 5.8e-09 36.6 0.6 8e-09 36.1 0.6 1.2 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase PKD_channel PF08016.12 RLN64829.1 - 5.2e-05 22.1 1.3 6.8e-05 21.7 1.3 1.1 1 0 0 1 1 1 1 Polycystin cation channel TMCO5 PF14992.6 RLN64829.1 - 0.00083 19.0 0.8 0.0018 17.9 0.8 1.5 1 1 0 1 1 1 1 TMCO5 family Fib_alpha PF08702.10 RLN64829.1 - 0.016 15.4 2.7 0.04 14.1 2.7 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Ion_trans PF00520.31 RLN64829.1 - 0.047 12.9 0.2 0.059 12.6 0.2 1.1 1 0 0 1 1 1 0 Ion transport protein Lipase_chap PF03280.14 RLN64829.1 - 0.071 13.1 4.7 0.31 11.0 2.6 2.2 2 0 0 2 2 2 0 Proteobacterial lipase chaperone protein CDH1_2_SANT_HL1 PF18375.1 RLN64829.1 - 0.073 13.8 1.1 0.073 13.8 1.1 2.0 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 Nup54 PF13874.6 RLN64829.1 - 0.14 12.3 4.4 0.12 12.4 2.3 1.9 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 UMPH-1 PF05822.12 RLN64830.1 - 9.3e-53 179.3 0.1 1e-52 179.1 0.1 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 RLN64830.1 - 0.0012 19.3 0.0 0.0026 18.2 0.0 1.6 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 RLN64831.1 - 2.6e-11 43.5 0.0 3.3e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) UMPH-1 PF05822.12 RLN64832.1 - 2.6e-65 220.4 0.0 2.3e-64 217.3 0.0 1.9 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 RLN64832.1 - 0.00017 22.1 0.4 0.0034 17.8 0.4 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 RLN64833.1 - 2.2e-69 233.8 0.0 3e-69 233.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN64833.1 - 2.1e-37 128.8 0.0 2.9e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN64833.1 - 0.00084 18.7 0.2 0.062 12.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 RLN64833.1 - 0.0037 16.7 1.6 0.0077 15.6 1.6 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3243 PF11588.8 RLN64834.1 - 0.095 13.0 0.2 0.47 10.8 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3243) RecO_N PF11967.8 RLN64834.1 - 0.14 12.2 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Recombination protein O N terminal PHM7_cyt PF14703.6 RLN64880.1 - 4.1e-07 30.4 0.3 8.8e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 RLN64880.1 - 1e-06 27.9 5.3 2.6e-05 23.3 0.1 2.8 3 0 0 3 3 3 2 Calcium-activated chloride channel Gal_Lectin PF02140.18 RLN64880.1 - 0.079 13.4 0.1 0.079 13.4 0.1 2.7 2 1 1 3 3 3 0 Galactose binding lectin domain DUF5415 PF17436.2 RLN64880.1 - 0.16 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5415) LeuA_dimer PF08502.10 RLN64881.1 - 4e-10 39.7 2.1 9.8e-10 38.4 2.1 1.6 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain baeRF_family7 PF18849.1 RLN64881.1 - 0.066 13.4 0.0 0.073 13.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 7 SAM_1 PF00536.30 RLN64882.1 - 3.1e-14 53.1 0.0 7.6e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RLN64882.1 - 1e-12 48.0 0.0 2.8e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_5 PF13857.6 RLN64882.1 - 5.6e-10 39.3 0.3 3.9e-06 27.0 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN64882.1 - 6.3e-08 33.1 0.0 2.7e-07 31.1 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN64882.1 - 1.1e-07 32.2 0.0 0.00012 22.5 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN64882.1 - 0.00048 20.4 0.4 0.64 10.6 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 RLN64882.1 - 0.00059 20.1 0.1 0.44 11.3 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat IQ PF00612.27 RLN64882.1 - 0.0096 15.6 35.4 0.45 10.4 0.2 7.1 7 0 0 7 7 7 4 IQ calmodulin-binding motif DUF3126 PF11324.8 RLN64882.1 - 0.74 9.7 3.9 12 5.8 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3126) BLOC1_2 PF10046.9 RLN64882.1 - 0.92 9.8 7.2 0.2 12.0 1.8 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PhoLip_ATPase_C PF16212.5 RLN64883.1 - 1.2e-64 218.4 29.8 1.2e-64 218.4 29.8 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RLN64883.1 - 2.9e-14 52.5 2.8 9.3e-14 50.9 2.8 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 RLN64883.1 - 2.8e-12 46.5 0.0 2.2e-11 43.7 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RLN64883.1 - 4.8e-10 40.1 0.1 0.0038 17.6 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RLN64883.1 - 2.2e-05 24.1 0.7 7.9e-05 22.3 0.0 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RLN64883.1 - 0.0027 17.5 0.0 0.0066 16.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Methyltransf_28 PF02636.17 RLN64884.1 - 0.062 12.9 0.6 1.4 8.5 0.3 2.4 2 1 1 3 3 3 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DPBB_1 PF03330.18 RLN64936.1 - 5.2e-08 33.1 0.2 1.3e-07 31.7 0.2 1.7 1 0 0 1 1 1 1 Lytic transglycolase Tmemb_9 PF05434.11 RLN64936.1 - 0.0049 16.8 0.0 0.0092 15.9 0.0 1.4 1 0 0 1 1 1 1 TMEM9 TMEM51 PF15345.6 RLN64936.1 - 0.0084 16.0 0.6 0.0084 16.0 0.6 1.7 2 0 0 2 2 2 1 Transmembrane protein 51 RIFIN PF02009.16 RLN64936.1 - 0.012 15.5 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Rifin Cadherin_C_2 PF16492.5 RLN64936.1 - 0.014 16.1 0.2 0.035 14.8 0.2 1.7 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal EphA2_TM PF14575.6 RLN64936.1 - 0.019 15.8 0.1 0.039 14.8 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 RLN64936.1 - 0.036 14.4 0.0 0.085 13.2 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) DUF3169 PF11368.8 RLN64936.1 - 0.049 13.1 0.0 0.072 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) TMEM154 PF15102.6 RLN64936.1 - 0.061 13.2 0.2 0.061 13.2 0.2 4.0 1 1 1 3 3 2 0 TMEM154 protein family CcmD PF04995.14 RLN64936.1 - 0.065 13.3 0.7 0.11 12.6 0.7 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) SID-1_RNA_chan PF13965.6 RLN64936.1 - 0.14 10.5 0.1 0.21 10.0 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SIT PF15330.6 RLN64936.1 - 0.31 11.5 1.0 0.96 9.9 0.0 2.2 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Nucleo_P87 PF07267.11 RLN64936.1 - 1.2 7.9 12.0 1.9 7.3 12.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ABC_membrane PF00664.23 RLN64937.1 - 4.4e-54 184.0 31.6 2.3e-34 119.3 8.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN64937.1 - 6.8e-48 162.7 0.0 5e-27 95.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter Dynamin_N PF00350.23 RLN64937.1 - 1.6e-06 28.3 0.1 0.00011 22.3 0.0 2.4 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 RLN64937.1 - 2e-06 27.9 0.1 0.091 12.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 RLN64937.1 - 3.2e-06 27.2 0.1 1.7 8.3 0.0 3.6 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN64937.1 - 9.3e-06 25.3 0.1 0.12 12.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 RLN64937.1 - 1.5e-05 24.6 3.0 2.1 7.7 0.1 4.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 RLN64937.1 - 0.0002 21.3 1.4 0.22 11.4 0.1 3.2 3 0 0 3 3 3 1 RsgA GTPase AAA_24 PF13479.6 RLN64937.1 - 0.0026 17.5 0.1 0.044 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 RLN64937.1 - 0.0031 17.7 0.3 0.12 12.4 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain DUF815 PF05673.13 RLN64937.1 - 0.004 16.3 0.1 1.7 7.7 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 RLN64937.1 - 0.0044 17.4 0.6 0.19 12.1 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 RLN64937.1 - 0.0076 16.8 0.1 1.4 9.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 RLN64937.1 - 0.011 15.1 0.1 0.52 9.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family SbcCD_C PF13558.6 RLN64937.1 - 0.018 15.3 0.0 3.9 7.8 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DEAD PF00270.29 RLN64937.1 - 0.019 14.7 0.0 0.06 13.1 0.0 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_15 PF13175.6 RLN64937.1 - 0.027 14.2 0.0 9.6 5.8 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 RLN64937.1 - 0.035 14.6 0.1 9.4 6.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 RLN64937.1 - 0.037 14.2 0.0 3 8.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 RLN64937.1 - 0.052 12.8 0.1 0.89 8.8 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 RLN64937.1 - 0.12 12.6 0.2 11 6.3 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 RLN64937.1 - 0.18 12.1 1.8 16 5.7 0.1 3.1 3 0 0 3 3 2 0 AAA domain IstB_IS21 PF01695.17 RLN64937.1 - 0.18 11.5 0.5 11 5.7 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein cobW PF02492.19 RLN64937.1 - 0.18 11.3 0.5 3.9 7.0 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.9 RLN64937.1 - 0.19 10.6 0.4 3.2 6.6 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 RLN64937.1 - 0.21 11.1 0.4 9.1 5.7 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 RLN64937.1 - 3.6 7.1 5.2 8.3 5.9 0.9 3.1 3 1 0 3 3 3 0 AAA domain ABC_membrane_3 PF13748.6 RLN64937.1 - 4.4 6.5 14.8 0.18 11.0 0.1 3.2 3 1 1 4 4 4 0 ABC transporter transmembrane region PepSY_TM PF03929.16 RLN64937.1 - 5.7 6.5 10.3 0.85 9.2 1.3 3.6 3 2 0 3 3 3 0 PepSY-associated TM region ABC_membrane PF00664.23 RLN64938.1 - 2.5e-61 207.8 27.9 2e-35 122.8 6.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN64938.1 - 4.2e-50 169.8 0.0 1.6e-28 99.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN64938.1 - 2.2e-09 37.1 0.6 0.015 14.7 0.0 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RLN64938.1 - 1.2e-07 31.8 0.0 0.023 14.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 RLN64938.1 - 2.5e-06 27.5 0.1 0.37 10.5 0.1 3.5 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN64938.1 - 3.7e-05 23.4 0.5 0.17 11.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 RLN64938.1 - 6.5e-05 23.0 0.3 0.0049 16.9 0.1 2.4 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.6 RLN64938.1 - 8.1e-05 23.2 0.0 0.64 10.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 RLN64938.1 - 0.00016 21.6 1.8 0.1 12.5 0.1 2.9 3 0 0 3 3 3 2 RsgA GTPase Roc PF08477.13 RLN64938.1 - 0.00037 20.7 0.0 1.1 9.5 0.0 2.9 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 RLN64938.1 - 0.00053 19.8 0.1 0.032 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 RLN64938.1 - 0.00062 18.8 0.3 0.0065 15.4 0.0 2.1 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 RLN64938.1 - 0.0011 18.3 0.2 0.11 11.9 0.1 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family DEAD PF00270.29 RLN64938.1 - 0.0022 17.8 0.0 0.041 13.6 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_18 PF13238.6 RLN64938.1 - 0.0029 18.1 0.0 1.5 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN64938.1 - 0.0029 18.0 0.1 0.23 11.8 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.19 RLN64938.1 - 0.0057 16.3 0.2 0.14 11.8 0.1 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 RLN64938.1 - 0.011 16.0 1.3 4.2 7.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 RLN64938.1 - 0.011 14.8 0.1 0.071 12.2 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 RLN64938.1 - 0.012 15.3 0.0 7.6 6.2 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 RLN64938.1 - 0.016 14.9 0.0 0.77 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Septin PF00735.18 RLN64938.1 - 0.017 14.4 0.0 0.31 10.3 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_7 PF12775.7 RLN64938.1 - 0.018 14.6 0.1 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 RLN64938.1 - 0.02 14.1 0.1 3.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SbcCD_C PF13558.6 RLN64938.1 - 0.027 14.7 0.0 5.9 7.2 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit KAP_NTPase PF07693.14 RLN64938.1 - 0.035 13.3 0.0 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 KAP family P-loop domain DUF87 PF01935.17 RLN64938.1 - 0.037 14.1 1.2 0.3 11.1 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Zeta_toxin PF06414.12 RLN64938.1 - 0.041 13.2 0.2 1.9 7.7 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin MobB PF03205.14 RLN64938.1 - 0.051 13.5 0.2 1.3 8.9 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 RLN64938.1 - 0.09 12.7 1.7 0.97 9.3 0.0 3.0 3 0 0 3 3 3 0 NACHT domain TsaE PF02367.17 RLN64938.1 - 0.11 12.5 0.4 1.8 8.5 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 RLN64938.1 - 0.11 12.2 0.2 5.6 6.7 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.29 RLN64938.1 - 0.13 12.6 0.0 7.2 7.0 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 RLN64938.1 - 0.14 12.3 0.0 2.4 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 RLN64938.1 - 0.18 11.0 0.2 3.6 6.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Cation_efflux PF01545.21 RLN64939.1 - 1.1e-46 159.1 3.7 1.1e-46 159.1 3.7 2.2 2 0 0 2 2 2 1 Cation efflux family DUF4106 PF13388.6 RLN64939.1 - 2.3 7.4 8.9 4.2 6.5 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) UIM PF02809.20 RLN64941.1 - 0.42 10.6 3.9 1.1 9.3 3.9 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif FAM199X PF15814.5 RLN64941.1 - 0.99 8.4 4.6 1.7 7.6 4.6 1.3 1 0 0 1 1 1 0 Protein family FAM199X Tugs PF17840.1 RLN64942.1 - 0.075 13.2 0.1 0.22 11.7 0.1 1.8 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain Peptidase_C48 PF02902.19 RLN64943.1 - 2.6e-14 53.6 0.0 3.8e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CN_hydrolase PF00795.22 RLN64943.1 - 7.4e-10 38.6 0.0 1.2e-08 34.7 0.0 2.2 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Ank_4 PF13637.6 RLN64944.1 - 4e-13 49.6 0.7 2.7e-09 37.4 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN64944.1 - 1e-11 44.7 0.3 0.0003 21.1 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 RLN64944.1 - 1.4e-09 38.4 0.1 2.2e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN64944.1 - 1.8e-08 34.4 0.1 0.0012 19.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN64944.1 - 2e-06 27.7 0.2 0.00099 19.4 0.1 2.7 3 0 0 3 3 3 2 Ankyrin repeat PHD PF00628.29 RLN64998.1 - 7.4e-10 38.6 8.7 1.4e-09 37.6 8.7 1.5 1 0 0 1 1 1 1 PHD-finger PLU-1 PF08429.11 RLN64998.1 - 0.00079 18.7 14.1 0.13 11.4 0.0 4.0 4 0 0 4 4 4 2 PLU-1-like protein PHD_3 PF13922.6 RLN64998.1 - 0.023 15.1 1.7 0.16 12.4 1.7 2.5 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.6 RLN64998.1 - 0.058 13.0 3.2 0.098 12.2 3.2 1.4 1 0 0 1 1 1 0 PHD-finger FlaC_arch PF05377.11 RLN64998.1 - 0.16 12.4 3.3 8.8 6.8 0.1 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DegS PF05384.11 RLN64998.1 - 2.7 7.5 7.6 8.3 5.9 0.2 3.2 3 0 0 3 3 3 0 Sensor protein DegS Filament PF00038.21 RLN64998.1 - 3 7.3 9.1 7.3 6.1 0.5 2.2 2 0 0 2 2 2 0 Intermediate filament protein zf-RING_2 PF13639.6 RLN64998.1 - 3.3 8.1 8.6 6.7 7.1 8.6 1.5 1 0 0 1 1 1 0 Ring finger domain TSGP1 PF07771.11 RLN65001.1 - 0.01 16.0 3.1 0.01 16.0 3.1 2.4 2 0 0 2 2 2 2 Tick salivary peptide group 1 CxC6 PF18721.1 RLN65001.1 - 1.8 8.9 4.5 5.1 7.5 4.5 1.8 1 1 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases Med24_N PF11277.8 RLN65001.1 - 6.9 4.6 8.1 11 4.0 8.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal CRM1_C PF08767.11 RLN65002.1 - 1.7e-102 342.9 11.9 5.7e-101 337.9 8.1 3.3 2 1 0 2 2 2 2 CRM1 C terminal Xpo1 PF08389.12 RLN65002.1 - 1.1e-30 106.6 13.0 4.3e-30 104.7 7.6 3.7 3 1 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_3 PF18787.1 RLN65002.1 - 3.3e-30 103.9 1.7 3.3e-30 103.9 1.7 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat_2 PF18784.1 RLN65002.1 - 4.7e-30 103.0 2.9 1.2e-29 101.7 2.9 1.8 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat PF18777.1 RLN65002.1 - 3.6e-17 61.6 0.3 8e-17 60.5 0.3 1.6 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 RLN65002.1 - 0.051 13.5 0.2 0.23 11.4 0.2 2.2 1 0 0 1 1 1 0 Importin-beta N-terminal domain zf-C3HC4_3 PF13920.6 RLN65003.1 - 1.1e-11 44.4 16.2 1.9e-11 43.6 16.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN65003.1 - 1.7e-06 27.7 15.1 4.1e-06 26.5 15.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 RRM_1 PF00076.22 RLN65003.1 - 7.2e-06 25.7 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.21 RLN65004.1 - 1.2e-24 87.3 1.2 5.6e-20 72.2 1.2 2.7 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Med3 PF11593.8 RLN65004.1 - 8.8 5.4 11.0 25 3.9 11.0 1.7 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SpoIIE PF07228.12 RLN65005.1 - 2.2e-08 34.3 0.0 3.3e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 RLN65005.1 - 3.7e-08 33.3 0.4 7.9e-08 32.2 0.4 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C ECM1 PF05782.11 RLN65005.1 - 0.019 13.9 1.0 0.03 13.3 1.0 1.2 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) DUF2985 PF11204.8 RLN65006.1 - 4e-12 46.1 1.5 8.3e-12 45.1 1.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Sdh_cyt PF01127.22 RLN65006.1 - 0.03 14.4 1.9 0.065 13.3 1.9 1.6 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2368 PF10166.9 RLN65006.1 - 0.17 11.5 0.9 0.55 9.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) WD40 PF00400.32 RLN65007.1 - 1.2e-10 41.8 0.0 0.0024 18.6 0.0 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN65007.1 - 0.0048 17.2 0.0 0.92 9.9 0.0 2.7 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RLN65007.1 - 0.0049 16.2 0.0 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain Glyco_hydro_38N PF01074.22 RLN65009.1 - 1.8e-36 126.0 2.4 2.1e-36 125.8 2.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Aminotran_1_2 PF00155.21 RLN65010.1 - 4.1e-05 22.9 0.0 7.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_C1 PF00112.23 RLN65092.1 - 6.5e-56 189.8 12.3 1.1e-55 189.0 12.3 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RLN65092.1 - 0.00059 18.7 0.5 0.048 12.4 0.1 2.5 2 0 0 2 2 2 2 Peptidase C1-like family CCDC53 PF10152.9 RLN65092.1 - 1.4 9.3 4.4 2.6 8.5 4.4 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Peptidase_C1 PF00112.23 RLN65094.1 - 5.6e-53 180.2 11.6 7.8e-53 179.8 11.6 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RLN65094.1 - 0.0033 16.3 0.8 0.098 11.4 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family DUF455 PF04305.14 RLN65095.1 - 5.1e-84 281.7 1.8 6.1e-84 281.4 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) DUF4180 PF13788.6 RLN65095.1 - 0.077 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4180) LRR_6 PF13516.6 RLN65138.1 - 1.1e-10 40.7 0.5 0.45 10.7 0.0 6.1 6 0 0 6 6 6 4 Leucine Rich repeat LRR_8 PF13855.6 RLN65138.1 - 0.0078 16.0 0.0 15 5.4 0.0 3.9 2 1 1 3 3 3 1 Leucine rich repeat Cellulose_synt PF03552.14 RLN65138.1 - 0.8 8.1 2.8 1.1 7.6 2.8 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF3537 PF12056.8 RLN65138.1 - 1 8.1 2.7 1.6 7.5 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) adh_short PF00106.25 RLN65139.1 - 2.5e-39 134.8 3.5 2.5e-38 131.5 3.5 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN65139.1 - 1.2e-27 97.0 3.1 2.1e-26 92.9 3.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN65139.1 - 6.7e-11 42.4 2.7 1.2e-05 25.3 1.0 2.6 2 1 0 2 2 2 2 KR domain DUF543 PF04418.12 RLN65139.1 - 0.037 14.0 0.6 0.09 12.8 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF543) HOASN PF14515.6 RLN65139.1 - 0.38 11.2 2.1 3.4 8.1 0.2 2.5 1 1 1 2 2 2 0 Haem-oxygenase-associated N-terminal helices Peptidase_M13_N PF05649.13 RLN65141.1 - 5.2e-74 250.2 0.0 6.5e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 RLN65141.1 - 7e-45 153.2 0.0 3e-44 151.1 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M13 UPRTase PF14681.6 RLN65149.1 - 3.9e-27 95.1 0.1 1.4e-26 93.2 0.1 1.8 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase RT_RNaseH_2 PF17919.1 RLN65149.1 - 0.03 14.3 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Pribosyltran PF00156.27 RLN65149.1 - 0.046 13.2 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain PEPCK_ATP PF01293.20 RLN65184.1 - 2.9e-219 728.5 0.0 3.4e-219 728.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 RLN65184.1 - 0.1 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Nramp PF01566.18 RLN65186.1 - 1.4e-102 343.3 13.3 1.4e-102 343.3 13.3 2.6 1 1 1 2 2 2 1 Natural resistance-associated macrophage protein SAE2 PF08573.10 RLN65187.1 - 3.6e-10 40.9 10.8 4.8e-06 27.6 0.4 3.4 3 1 1 4 4 4 2 DNA repair protein endonuclease SAE2/CtIP C-terminus Striatin PF08232.12 RLN65187.1 - 0.26 11.9 5.3 1.5 9.4 5.3 2.1 1 1 0 1 1 1 0 Striatin family IP_trans PF02121.18 RLN65188.1 - 7e-88 294.4 0.1 8.4e-88 294.1 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein GlutR_dimer PF00745.20 RLN65189.1 - 0.012 16.1 2.4 0.24 11.9 0.1 2.7 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Osmo_CC PF08946.10 RLN65189.1 - 0.66 10.3 4.1 4.3 7.7 0.1 3.0 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Hid1 PF12722.7 RLN65190.1 - 1.1e-30 106.5 0.1 1.3e-30 106.2 0.1 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 RLN65190.1 - 1.2e-23 83.4 0.0 1.4e-23 83.2 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Ku_PK_bind PF08785.11 RLN65190.1 - 0.17 12.0 0.3 2.5 8.3 0.0 2.0 1 1 1 2 2 2 0 Ku C terminal domain like DNA_pol_phi PF04931.13 RLN65194.1 - 0.89 7.6 4.0 0.77 7.8 4.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Fer2 PF00111.27 RLN65202.1 - 1.2e-09 37.9 0.2 1.9e-09 37.4 0.2 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Ion_trans PF00520.31 RLN65203.1 - 2.3e-13 49.9 16.3 9e-08 31.6 3.2 3.0 2 1 1 3 3 3 2 Ion transport protein cNMP_binding PF00027.29 RLN65203.1 - 3.1e-12 46.4 0.1 1.6e-11 44.1 0.1 2.1 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 RLN65203.1 - 7.3e-12 45.1 5.4 1.6e-11 44.0 5.4 1.7 1 0 0 1 1 1 1 Ion channel DDE_1 PF03184.19 RLN65206.1 - 0.00029 20.5 0.2 0.13 11.9 0.0 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN65206.1 - 0.0018 18.2 0.0 0.005 16.8 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain TagF_N PF09867.9 RLN65206.1 - 0.068 13.2 0.1 0.51 10.4 0.0 2.2 3 0 0 3 3 3 0 TagF N-terminal domain, Type VI secretion system-associated DUF4267 PF14087.6 RLN65206.1 - 0.14 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) WW PF00397.26 RLN65269.1 - 0.00014 21.9 0.1 0.00049 20.1 0.0 1.9 2 0 0 2 2 2 1 WW domain APH PF01636.23 RLN65269.1 - 1.9 8.4 8.3 0.28 11.1 3.5 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family PCI PF01399.27 RLN65270.1 - 1.4e-13 51.2 0.0 3.7e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 PCI domain eIF3m_C_helix PF18005.1 RLN65270.1 - 0.0038 16.9 0.8 0.0089 15.7 0.0 2.1 3 0 0 3 3 3 1 eIF3 subunit M, C-terminal helix CSN8_PSD8_EIF3K PF10075.9 RLN65270.1 - 0.0064 16.5 1.8 0.013 15.5 0.0 2.3 3 0 0 3 3 3 1 CSN8/PSMD8/EIF3K family Pkinase PF00069.25 RLN65271.1 - 1e-59 202.0 0.2 1.6e-59 201.4 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain PP2C PF00481.21 RLN65271.1 - 2.7e-55 187.8 0.0 5.3e-55 186.8 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase_Tyr PF07714.17 RLN65271.1 - 6.1e-38 130.6 0.1 9e-38 130.0 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN65271.1 - 6.8e-07 28.9 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RLN65271.1 - 0.00053 18.9 0.0 0.00053 18.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 RLN65271.1 - 0.017 14.7 0.7 0.039 13.5 0.7 1.6 1 0 0 1 1 1 0 RIO1 family Macoilin PF09726.9 RLN65272.1 - 4.7 5.6 14.6 6.9 5.1 14.6 1.2 1 0 0 1 1 1 0 Macoilin family CUE PF02845.16 RLN65273.1 - 0.18 11.5 0.2 4.8 7.0 0.0 2.6 2 0 0 2 2 2 0 CUE domain Tautomerase PF01361.21 RLN65273.1 - 1.5 8.8 4.7 0.64 10.0 0.1 2.5 3 0 0 3 3 3 0 Tautomerase enzyme EGF_MSP1_1 PF12946.7 RLN65274.1 - 4 7.6 6.8 12 6.0 0.2 3.2 3 0 0 3 3 3 0 MSP1 EGF domain 1 PIG-U PF06728.13 RLN65276.1 - 3e-66 224.0 22.3 1.6e-46 159.1 10.2 3.0 1 1 2 3 3 3 3 GPI transamidase subunit PIG-U Arif-1 PF06770.11 RLN65276.1 - 0.022 14.4 5.4 0.21 11.2 0.2 2.8 2 1 1 3 3 3 0 Actin-rearrangement-inducing factor (Arif-1) Mntp PF02659.15 RLN65276.1 - 0.063 13.0 1.3 0.095 12.5 0.1 1.9 2 0 0 2 2 2 0 Putative manganese efflux pump 8TM_micro PF17028.5 RLN65276.1 - 0.37 10.4 7.7 0.63 9.7 7.7 1.4 1 0 0 1 1 1 0 8TM Microsporidial transmembrane domain MCM_bind PF09739.9 RLN65277.1 - 5.5e-79 266.2 0.0 5.8e-74 249.6 0.0 2.1 2 0 0 2 2 2 2 Mini-chromosome maintenance replisome factor RabGAP-TBC PF00566.18 RLN65278.1 - 1.8e-20 73.5 0.0 2.9e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DSPc PF00782.20 RLN65278.1 - 2.8e-11 43.4 0.0 5.3e-11 42.5 0.0 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RLN65278.1 - 0.013 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RLN65278.1 - 0.019 14.9 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family EF-hand_1 PF00036.32 RLN65278.1 - 0.093 12.3 0.2 0.47 10.1 0.0 2.2 2 0 0 2 2 2 0 EF hand Tn7_Tnp_TnsA_C PF08721.11 RLN65279.1 - 0.17 12.6 0.1 0.54 10.9 0.1 1.9 1 0 0 1 1 1 0 TnsA endonuclease C terminal UPF0242 PF06785.11 RLN65280.1 - 0.55 10.3 4.7 3.3 7.8 4.7 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus WW PF00397.26 RLN65281.1 - 1.1e-08 35.0 12.0 9.2e-07 28.9 4.1 2.6 2 0 0 2 2 2 2 WW domain IQ PF00612.27 RLN65281.1 - 0.021 14.6 0.0 0.084 12.7 0.0 2.0 2 0 0 2 2 2 0 IQ calmodulin-binding motif Ank_2 PF12796.7 RLN65281.1 - 0.028 15.0 0.1 0.064 13.9 0.1 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) CDC73_C PF05179.14 RLN65282.1 - 1.3e-17 63.9 0.0 8.9e-14 51.5 0.0 2.5 2 0 0 2 2 2 2 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 RLN65282.1 - 1.1e-14 54.4 3.7 3.6e-13 49.5 3.7 2.6 1 1 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal Ion_trans PF00520.31 RLN65282.1 - 1.3e-05 24.6 2.1 2.6e-05 23.6 2.1 1.5 1 0 0 1 1 1 1 Ion transport protein BCIP PF13862.6 RLN65282.1 - 0.1 12.4 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 p21-C-terminal region-binding protein Rhabdo_NV PF02484.15 RLN65282.1 - 0.11 12.7 0.2 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 Rhabdovirus Non-virion protein Methyltransf_23 PF13489.6 RLN65283.1 - 1.3e-20 73.9 0.0 2.1e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Robl_LC7 PF03259.17 RLN65283.1 - 6.1e-15 54.8 0.0 1.1e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Roadblock/LC7 domain Methyltransf_25 PF13649.6 RLN65283.1 - 4.6e-14 52.9 0.1 9.9e-14 51.8 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN65283.1 - 5.3e-13 49.4 0.0 1.3e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN65283.1 - 3.8e-10 39.5 0.0 6.6e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 RLN65283.1 - 5.3e-08 33.5 0.1 1.4e-07 32.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN65283.1 - 2.9e-06 27.1 0.0 5.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain LAMTOR5 PF16672.5 RLN65283.1 - 0.03 14.3 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 STAS_2 PF13466.6 RLN65283.1 - 0.19 12.1 1.9 0.25 11.7 0.4 2.0 2 0 0 2 2 2 0 STAS domain Fer2_3 PF13085.6 RLN65287.1 - 3.1e-21 75.4 0.7 2e-20 72.8 0.7 2.0 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 RLN65287.1 - 0.00055 19.8 0.9 0.0011 18.9 0.9 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF4461 PF14688.6 RLN65288.1 - 6e-61 206.9 0.0 9.5e-61 206.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) DUF4460 PF14687.6 RLN65288.1 - 2.5e-05 24.3 0.1 0.00023 21.2 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4460) Methyltransf_25 PF13649.6 RLN65289.1 - 1.8e-06 28.6 0.0 7.2e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN65289.1 - 6.7e-06 26.7 0.0 3.4e-05 24.4 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN65289.1 - 0.00013 22.7 0.0 0.0019 18.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain IBR PF01485.21 RLN65290.1 - 1.3e-10 41.4 34.5 8.2e-08 32.4 6.0 3.4 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 RLN65290.1 - 2.1e-06 27.5 2.9 2.1e-06 27.5 2.9 4.1 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN65290.1 - 2.5e-06 27.2 2.4 2.5e-06 27.2 2.4 4.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN65290.1 - 4.2e-06 26.7 2.4 4.2e-06 26.7 2.4 3.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 RLN65290.1 - 5.7e-06 26.6 2.6 5.7e-06 26.6 2.6 4.0 3 1 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 RLN65290.1 - 0.0001 22.2 4.7 0.0001 22.2 4.7 4.6 4 1 0 4 4 4 1 zinc-RING finger domain BRI3BP PF14965.6 RLN65290.1 - 0.65 9.5 4.1 1.5 8.3 4.1 1.5 1 0 0 1 1 1 0 Negative regulator of p53/TP53 Ank_2 PF12796.7 RLN65315.1 - 3.4e-38 130.1 6.1 6.2e-10 39.5 0.3 6.8 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN65315.1 - 5.6e-28 96.9 15.5 0.0025 18.4 0.0 10.8 4 2 8 12 12 12 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN65315.1 - 2.7e-24 84.9 12.9 0.37 11.2 0.1 13.6 8 3 7 15 15 15 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN65315.1 - 6.4e-23 78.4 5.5 0.46 11.2 0.0 13.9 15 0 0 15 15 15 3 Ankyrin repeat Ank PF00023.30 RLN65315.1 - 9.1e-09 35.4 3.0 14 6.3 0.0 9.9 9 1 1 10 10 10 1 Ankyrin repeat DUF5049 PF16468.5 RLN65315.1 - 0.057 13.3 1.0 27 4.7 0.0 4.9 5 1 1 6 6 6 0 Domain of unknown function (DUF5049) Pyr_redox_2 PF07992.14 RLN65316.1 - 2.4e-64 217.4 1.9 3.4e-64 216.9 1.9 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 RLN65316.1 - 2.4e-31 108.3 4.8 2.6e-31 108.2 1.7 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 RLN65316.1 - 9e-22 77.4 3.3 5e-18 65.5 0.1 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RLN65316.1 - 4.5e-13 49.1 1.2 3.3e-12 46.3 1.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RLN65316.1 - 5.7e-07 29.2 0.5 2e-05 24.1 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 RLN65316.1 - 1.1e-05 24.8 6.8 6.7e-05 22.1 1.4 2.8 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 RLN65316.1 - 1.3e-05 24.1 1.7 0.00056 18.7 0.6 2.6 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.6 RLN65316.1 - 0.00037 20.7 0.6 0.0009 19.4 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 RLN65316.1 - 0.00047 19.4 0.0 0.0011 18.1 0.0 1.7 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 RLN65316.1 - 0.00072 19.2 7.5 0.0024 17.5 1.1 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 RLN65316.1 - 0.0016 17.8 0.5 0.0038 16.5 0.5 1.6 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 RLN65316.1 - 0.0022 17.2 0.7 0.0041 16.2 0.7 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 RLN65316.1 - 0.024 14.0 1.1 7.2 5.9 0.0 2.9 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 RLN65316.1 - 0.029 14.8 0.1 3.1 8.3 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 RLN65316.1 - 0.05 12.9 4.0 0.25 10.6 0.3 2.9 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 RLN65316.1 - 0.1 11.8 1.3 0.25 10.6 1.3 1.6 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 RLN65316.1 - 0.55 10.1 3.0 5.1 6.9 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 RLN65316.1 - 3 8.5 4.8 50 4.6 0.3 3.1 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Peptidase_S49_N PF08496.10 RLN65317.1 - 5.7 7.0 19.8 0.44 10.6 4.1 2.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal EIIBC-GUT_N PF03612.14 RLN65317.1 - 5.8 6.6 10.8 12 5.6 1.7 2.7 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4471 PF14740.6 RLN65317.1 - 7.3 5.7 10.7 3.2 6.9 2.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) PspA_IM30 PF04012.12 RLN65349.1 - 1.4 8.4 13.4 0.094 12.3 7.7 1.8 2 0 0 2 2 2 0 PspA/IM30 family Prothymosin PF03247.14 RLN65349.1 - 3 8.3 17.5 13 6.3 15.0 2.4 2 0 0 2 2 2 0 Prothymosin/parathymosin family Mucin PF01456.17 RLN65353.1 - 0.014 15.4 14.4 0.018 15.0 14.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein ABC_tran PF00005.27 RLN65391.1 - 3.7e-43 147.3 1.2 6.3e-20 72.1 0.0 3.7 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 RLN65391.1 - 7.9e-17 62.0 9.3 0.00072 19.4 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RLN65391.1 - 2.1e-09 37.2 0.0 0.0026 17.2 0.0 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain NACHT PF05729.12 RLN65391.1 - 7.9e-08 32.4 0.2 0.00056 19.9 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 RLN65391.1 - 5e-07 30.3 3.1 0.025 15.0 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 RLN65391.1 - 9.4e-07 28.5 0.1 0.032 14.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN65391.1 - 6e-06 26.6 1.8 0.068 13.5 0.9 3.4 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 RLN65391.1 - 6.8e-06 26.1 0.1 0.13 12.2 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_14 PF13173.6 RLN65391.1 - 1.3e-05 25.3 0.1 0.11 12.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 RLN65391.1 - 2.8e-05 24.0 4.6 0.25 11.0 0.0 3.6 4 0 0 4 4 3 2 AAA ATPase domain AAA_28 PF13521.6 RLN65391.1 - 4.7e-05 23.7 0.4 0.26 11.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 RLN65391.1 - 6.3e-05 23.3 0.0 0.52 10.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_23 PF13476.6 RLN65391.1 - 6.4e-05 23.5 15.0 0.0099 16.4 5.1 3.3 3 1 0 3 3 3 2 AAA domain ABC_tran_Xtn PF12848.7 RLN65391.1 - 9.2e-05 22.4 8.9 9.2e-05 22.4 8.9 2.2 2 0 0 2 2 1 1 ABC transporter IstB_IS21 PF01695.17 RLN65391.1 - 0.00011 21.9 0.1 0.31 10.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA PF00004.29 RLN65391.1 - 0.00021 21.7 0.0 0.72 10.3 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 RLN65391.1 - 0.00023 21.2 0.0 1.2 9.2 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_7 PF12775.7 RLN65391.1 - 0.00035 20.1 0.1 0.19 11.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region TsaE PF02367.17 RLN65391.1 - 0.00043 20.3 0.3 0.13 12.3 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 RLN65391.1 - 0.00093 19.4 2.2 1.5 9.0 0.5 3.6 3 1 0 3 3 3 2 AAA domain PduV-EutP PF10662.9 RLN65391.1 - 0.0012 18.6 0.1 0.14 11.9 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 RLN65391.1 - 0.0012 19.3 0.0 1.3 9.5 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 RLN65391.1 - 0.0013 18.5 0.6 2.2 8.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 RLN65391.1 - 0.0029 17.6 1.9 3.3 7.7 0.3 3.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 RLN65391.1 - 0.003 17.2 2.6 0.16 11.6 0.0 3.2 4 0 0 4 4 4 1 AAA domain Roc PF08477.13 RLN65391.1 - 0.0038 17.4 0.0 2.4 8.4 0.0 2.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ATP-synt_ab PF00006.25 RLN65391.1 - 0.0056 16.4 0.0 1.4 8.5 0.0 2.7 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 RLN65391.1 - 0.0057 16.4 7.5 0.065 12.9 0.0 3.7 3 2 0 3 3 3 1 AAA domain SRP54 PF00448.22 RLN65391.1 - 0.0066 16.1 0.2 2.1 7.9 0.1 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 RLN65391.1 - 0.0075 16.2 0.3 5.9 6.7 0.0 2.8 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 RLN65391.1 - 0.01 15.0 0.7 3.1 6.9 0.0 2.7 3 0 0 3 3 2 0 NB-ARC domain Bac_DnaA PF00308.18 RLN65391.1 - 0.013 15.3 0.0 4.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_27 PF13514.6 RLN65391.1 - 0.015 14.9 1.0 1.5 8.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 RLN65391.1 - 0.031 14.2 1.6 6.2 6.7 0.0 3.0 4 0 0 4 4 2 0 NTPase RuvB_N PF05496.12 RLN65391.1 - 0.043 13.6 0.6 2.8 7.7 0.0 2.9 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain MeaB PF03308.16 RLN65391.1 - 0.36 9.8 4.7 0.92 8.4 0.0 3.3 3 1 1 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad17 PF03215.15 RLN65391.1 - 0.36 10.7 1.3 10 6.0 0.0 3.0 4 0 0 4 4 2 0 Rad17 P-loop domain cobW PF02492.19 RLN65391.1 - 0.58 9.7 2.4 12 5.5 0.0 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Thymidylate_kin PF02223.17 RLN65391.1 - 1.1 9.0 4.8 2.2 7.9 0.0 3.0 3 0 0 3 3 2 0 Thymidylate kinase Ank_2 PF12796.7 RLN65392.1 - 7e-16 58.6 0.1 7.9e-05 23.2 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 RLN65392.1 - 3.6e-14 52.5 0.1 0.00021 21.6 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 RLN65392.1 - 2e-13 49.2 0.1 7e-05 22.9 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 RLN65392.1 - 8e-11 42.3 0.1 4.5e-07 30.3 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN65392.1 - 2.5e-08 34.0 0.1 0.0062 16.8 0.1 4.4 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Dynamin_N PF00350.23 RLN65393.1 - 4.8e-12 46.3 0.0 1.4e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 RLN65393.1 - 7.2e-07 29.3 0.0 6.3e-06 26.3 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RLN65393.1 - 0.00047 20.6 0.6 0.0025 18.2 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain CBM-like PF14683.6 RLN65393.1 - 0.00074 19.4 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III RsgA_GTPase PF03193.16 RLN65393.1 - 0.0022 17.9 0.0 0.037 13.9 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 RLN65393.1 - 0.0095 15.3 0.0 0.027 13.8 0.0 1.7 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Vps35 PF03635.17 RLN65393.1 - 0.064 11.8 0.3 0.1 11.1 0.3 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 Sigma70_r4_2 PF08281.12 RLN65393.1 - 0.069 12.8 0.0 1.1 8.9 0.0 2.8 3 0 0 3 3 3 0 Sigma-70, region 4 T2SSE PF00437.20 RLN65393.1 - 0.074 12.1 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RCC1 PF00415.18 RLN65423.1 - 1.4e-50 169.6 24.3 4.8e-11 43.1 0.2 8.1 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN65423.1 - 9.8e-30 101.7 36.8 2.8e-10 39.7 0.2 7.4 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Ank PF00023.30 RLN65423.1 - 4.6e-05 23.7 0.3 0.00011 22.5 0.3 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 RLN65423.1 - 7.8e-05 22.8 0.1 0.00022 21.4 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 RLN65423.1 - 8.4e-05 23.1 0.1 0.00019 21.9 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN65423.1 - 0.0004 20.6 0.3 0.00089 19.5 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN65423.1 - 0.0025 18.4 0.0 0.0076 16.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Thx PF17070.5 RLN65423.1 - 0.033 14.3 0.4 0.15 12.3 0.4 2.1 1 0 0 1 1 1 0 30S ribosomal protein Thx DUF4550 PF15084.6 RLN65423.1 - 0.23 11.9 0.0 0.47 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4550) DUF4698 PF15769.5 RLN65424.1 - 0.00066 18.9 0.3 0.0012 18.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4698) PI3_PI4_kinase PF00454.27 RLN65425.1 - 1.7e-25 90.3 0.0 2.3e-21 76.8 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase ubiquitin PF00240.23 RLN65426.1 - 1.4e-10 40.8 0.0 2.1e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_5 PF18037.1 RLN65426.1 - 0.16 12.4 0.0 0.24 11.8 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain PHTB1_N PF14727.6 RLN65427.1 - 1.4e-59 202.5 0.0 1.7e-59 202.3 0.0 1.0 1 0 0 1 1 1 1 PTHB1 N-terminus FAT PF02259.23 RLN65480.1 - 9e-33 113.9 7.1 5.6e-31 108.0 4.8 3.1 2 1 0 2 2 2 1 FAT domain DUF3385 PF11865.8 RLN65480.1 - 4.4e-26 91.7 0.7 3.4e-20 72.6 0.1 4.3 3 1 1 4 4 4 3 Domain of unknown function (DUF3385) TPR_19 PF14559.6 RLN65480.1 - 1.9e-06 28.3 0.0 0.15 12.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat HEAT_EZ PF13513.6 RLN65480.1 - 0.004 17.6 2.4 0.7 10.5 0.1 4.2 3 1 1 4 4 4 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 RLN65480.1 - 0.012 16.2 0.7 0.57 10.8 0.1 2.9 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Glyco_hydro_3_C PF01915.22 RLN65496.1 - 5e-52 176.8 0.0 6.9e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RLN65496.1 - 2.8e-07 30.6 0.0 6.4e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PEP_hydrolase PF09370.10 RLN65496.1 - 0.071 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like AAR2 PF05282.11 RLN65532.1 - 2.2e-23 83.2 0.0 2.7e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein DUF402 PF04167.13 RLN65532.1 - 0.094 12.9 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF402) BAR_3 PF16746.5 RLN65534.1 - 1.5e-09 37.9 5.7 2.1e-09 37.4 5.7 1.1 1 0 0 1 1 1 1 BAR domain of APPL family DUF4398 PF14346.6 RLN65534.1 - 0.006 17.2 6.1 0.006 17.2 6.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4398) DUF4745 PF15923.5 RLN65534.1 - 0.037 14.0 1.0 0.055 13.4 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4745) FapA PF03961.13 RLN65534.1 - 0.24 10.0 0.5 0.38 9.3 0.3 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 RLN65534.1 - 0.83 9.8 3.9 0.47 10.6 1.3 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Acyl_transf_1 PF00698.21 RLN65535.1 - 3.3e-30 105.7 4.3 3.8e-30 105.5 4.3 1.0 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 RLN65535.1 - 0.1 12.3 2.9 0.66 9.7 2.9 2.1 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis MIF4G PF02854.19 RLN65537.1 - 3.8e-42 144.3 8.7 5e-28 98.2 4.4 2.5 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.17 RLN65537.1 - 0.0028 17.6 1.0 0.019 14.9 0.6 2.6 2 0 0 2 2 2 1 MA3 domain AAA_assoc_C PF09821.9 RLN65537.1 - 0.033 14.7 0.9 4 8.0 0.0 2.8 2 1 0 2 2 2 0 C-terminal AAA-associated domain Dicty_REP PF05086.12 RLN65537.1 - 8.2 4.3 15.3 14 3.5 15.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MULE PF10551.9 RLN65539.1 - 2.5e-12 47.0 0.1 7e-12 45.6 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 RLN65539.1 - 0.021 15.5 0.1 0.051 14.3 0.1 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain LPMO_10 PF03067.15 RLN65540.1 - 4.6e-16 60.1 0.1 2.7e-08 34.7 0.1 2.7 2 1 0 2 2 2 2 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 RLN65540.1 - 0.044 13.7 0.5 5.8 6.8 0.1 3.2 1 1 0 2 2 2 0 Glycosyl hydrolase family 61 Oxidored_FMN PF00724.20 RLN65585.1 - 2.9e-77 260.2 0.0 4.4e-77 259.6 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Ank_2 PF12796.7 RLN65585.1 - 1.8e-18 66.9 0.0 7.3e-06 26.5 0.1 6.0 3 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN65585.1 - 2.4e-16 59.9 0.1 1.9e-05 25.1 0.0 6.6 4 3 1 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN65585.1 - 1.3e-11 44.5 4.6 0.5 10.8 0.0 8.0 6 2 3 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN65585.1 - 2.5e-10 39.7 0.9 8.4 7.3 0.0 8.9 10 0 0 10 10 10 2 Ankyrin repeat DUF3671 PF12420.8 RLN65586.1 - 0.069 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function TauE PF01925.19 RLN65586.1 - 0.088 12.4 4.2 0.077 12.6 0.7 2.4 3 0 0 3 3 3 0 Sulfite exporter TauE/SafE Pkinase_Tyr PF07714.17 RLN65587.1 - 9.4e-10 38.2 0.0 1.7e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN65587.1 - 3.8e-09 36.3 0.0 9.7e-09 35.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain DUF4214 PF13946.6 RLN65587.1 - 0.085 12.9 0.2 0.27 11.3 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) Aldedh PF00171.22 RLN65588.1 - 1.1e-129 432.9 0.0 1.3e-129 432.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MAD PF05557.13 RLN65589.1 - 9.4e-28 97.0 76.0 6.6e-26 90.9 76.0 3.2 1 1 0 1 1 1 1 Mitotic checkpoint protein ADIP PF11559.8 RLN65589.1 - 0.0049 17.0 70.7 0.36 10.9 13.7 6.5 4 2 1 6 6 6 5 Afadin- and alpha -actinin-Binding COMM_domain PF07258.14 RLN65589.1 - 1.2 9.3 9.3 0.11 12.6 0.9 3.3 3 1 0 3 3 3 0 COMM domain DLH PF01738.18 RLN65590.1 - 3.3e-17 62.8 0.0 4.3e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family HECT PF00632.25 RLN65591.1 - 8.5e-79 265.2 0.3 1.2e-78 264.7 0.3 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) fn3 PF00041.21 RLN65591.1 - 6.6e-18 64.8 0.5 7.4e-08 32.6 0.1 2.8 2 0 0 2 2 2 2 Fibronectin type III domain WW PF00397.26 RLN65591.1 - 0.00095 19.2 0.4 0.00095 19.2 0.4 2.7 3 0 0 3 3 3 1 WW domain DUF2826 PF11442.8 RLN65592.1 - 0.035 14.0 0.1 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2826) ALO PF04030.14 RLN65593.1 - 1.3e-20 74.3 1.2 1.4e-19 70.9 1.2 2.1 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 RLN65593.1 - 2.1e-17 63.2 0.0 3.7e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BAG PF02179.16 RLN65594.1 - 0.03 14.8 1.7 0.039 14.4 0.3 2.0 2 0 0 2 2 2 0 BAG domain NAM-associated PF14303.6 RLN65595.1 - 0.025 15.3 0.5 0.96 10.1 0.2 2.5 1 1 0 2 2 2 0 No apical meristem-associated C-terminal domain Dynactin_p62 PF05502.13 RLN65596.1 - 1.8e-15 56.7 12.1 9.3e-14 51.1 9.3 3.3 2 1 0 2 2 2 1 Dynactin p62 family MTBP_mid PF14919.6 RLN65596.1 - 0.38 9.9 3.0 0.59 9.3 3.0 1.2 1 0 0 1 1 1 0 MDM2-binding DUF2225 PF09986.9 RLN65597.1 - 0.11 12.2 0.0 0.81 9.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Gram_pos_anchor PF00746.21 RLN65642.1 - 0.043 13.8 0.1 0.097 12.6 0.1 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Alg6_Alg8 PF03155.15 RLN65643.1 - 5.2e-99 332.4 14.7 8.5e-84 282.2 8.7 2.0 1 1 1 2 2 2 2 ALG6, ALG8 glycosyltransferase family Peptidase_M14 PF00246.24 RLN65644.1 - 1.9e-11 44.3 0.0 3.5e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 RLN65644.1 - 4.5e-11 43.1 0.1 1.3e-10 41.5 0.1 1.8 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Ion_trans_2 PF07885.16 RLN65647.1 - 3.5e-09 36.5 5.3 8.3e-09 35.3 5.3 1.6 1 0 0 1 1 1 1 Ion channel SK_channel PF03530.14 RLN65647.1 - 0.00033 20.6 0.1 0.00062 19.7 0.1 1.5 1 0 0 1 1 1 1 Calcium-activated SK potassium channel Ion_trans PF00520.31 RLN65647.1 - 0.0041 16.4 0.6 0.0077 15.5 0.6 1.4 1 0 0 1 1 1 1 Ion transport protein Arteri_Gl PF00951.18 RLN65647.1 - 0.0087 15.9 2.1 0.0087 15.9 2.1 2.0 2 0 0 2 2 2 1 Arterivirus GL envelope glycoprotein Romo1 PF10247.9 RLN65647.1 - 0.065 13.6 1.9 0.076 13.4 0.3 1.9 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Homeobox_KN PF05920.11 RLN65648.1 - 1.3e-20 72.9 4.4 5.5e-12 45.4 0.1 3.0 3 0 0 3 3 3 2 Homeobox KN domain Homeodomain PF00046.29 RLN65648.1 - 1.2e-07 31.5 0.1 0.018 14.9 0.0 2.7 2 0 0 2 2 2 2 Homeodomain Ad_cyc_g-alpha PF08509.11 RLN65648.1 - 0.19 11.5 0.6 14 5.5 0.1 3.0 2 0 0 2 2 2 0 Adenylate cyclase G-alpha binding domain PhyH PF05721.13 RLN65649.1 - 1.2e-07 32.2 0.0 2.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) adh_short PF00106.25 RLN65650.1 - 1.7e-33 115.7 0.6 2.3e-33 115.3 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN65650.1 - 6.3e-26 91.4 0.6 3.3e-25 89.0 0.7 1.8 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN65650.1 - 1.1e-06 28.6 0.9 3e-06 27.3 0.9 1.7 1 1 0 1 1 1 1 KR domain DNA_pol_B_thumb PF14791.6 RLN65651.1 - 0.031 14.4 0.0 0.15 12.2 0.0 2.1 1 1 0 1 1 1 0 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 RLN65651.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase beta palm Ammonium_transp PF00909.21 RLN65652.1 - 2.6e-62 210.8 21.2 3.4e-62 210.4 21.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family S_4TM PF18159.1 RLN65652.1 - 0.22 10.8 1.1 20 4.3 0.0 2.7 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain Ammonium_transp PF00909.21 RLN65653.1 - 3.5e-65 220.2 21.8 4.5e-65 219.9 21.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pyr_redox_2 PF07992.14 RLN65653.1 - 0.0013 18.0 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF3099 PF11298.8 RLN65653.1 - 0.015 15.4 0.9 0.053 13.7 0.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) Trp_oprn_chp PF09534.10 RLN65653.1 - 9.4 6.0 9.9 15 5.3 5.5 2.4 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Tyrosinase PF00264.20 RLN65654.1 - 3.7e-23 83.0 0.3 1.6e-22 80.9 0.1 2.1 2 1 0 2 2 2 1 Common central domain of tyrosinase CBM_25 PF03423.13 RLN65655.1 - 1.3e-12 47.9 5.6 1.3e-12 47.9 5.6 2.4 2 0 0 2 2 2 1 Carbohydrate binding domain (family 25) Alpha-amylase PF00128.24 RLN65655.1 - 1e-11 45.0 0.0 3.9e-11 43.1 0.0 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CBM53 PF16760.5 RLN65655.1 - 8.5e-11 42.3 4.3 1.1e-10 41.9 2.5 2.2 2 0 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) CBM26 PF16738.5 RLN65655.1 - 0.019 15.2 1.6 0.019 15.2 1.6 2.5 3 0 0 3 3 3 0 Starch-binding module 26 CBM_25 PF03423.13 RLN65656.1 - 2.6e-13 50.1 7.1 2.6e-13 50.1 7.1 2.5 2 0 0 2 2 2 1 Carbohydrate binding domain (family 25) CBM53 PF16760.5 RLN65656.1 - 2.9e-11 43.8 3.0 2.9e-11 43.8 3.0 2.2 2 0 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) Alpha-amylase PF00128.24 RLN65656.1 - 2.3e-08 34.0 0.0 5.1e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CBM26 PF16738.5 RLN65656.1 - 0.0055 16.9 2.6 0.022 15.0 2.6 2.0 1 0 0 1 1 1 1 Starch-binding module 26 PseudoU_synth_2 PF00849.22 RLN65657.1 - 7.8e-09 35.8 0.0 2.3e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 RLN65657.1 - 0.15 11.8 0.1 0.34 10.7 0.1 1.6 1 0 0 1 1 1 0 S4 domain DUF1126 PF06565.12 RLN65658.1 - 3.3e-78 258.3 0.1 2.1e-27 95.0 0.0 3.4 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 RLN65658.1 - 0.00012 22.4 1.5 0.37 11.3 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN65658.1 - 0.00044 20.0 0.1 0.69 10.0 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RLN65658.1 - 0.011 15.2 0.0 3.4 7.4 0.0 3.3 3 0 0 3 3 3 0 EF hand Nop PF01798.18 RLN65659.1 - 1.2e-88 296.4 0.2 1.2e-88 296.4 0.2 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 RLN65659.1 - 2.4e-17 63.0 0.1 2.4e-17 63.0 0.1 2.8 3 0 0 3 3 3 1 NOP5NT (NUC127) domain DUF913 PF06025.12 RLN65659.1 - 9.3 5.1 9.7 14 4.5 9.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CN_hydrolase PF00795.22 RLN65660.1 - 3e-68 230.0 0.0 3.4e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PAP_fibrillin PF04755.12 RLN65661.1 - 0.016 15.2 0.1 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 PAP_fibrillin NUFIP1 PF10453.9 RLN65661.1 - 0.022 14.6 0.0 0.062 13.2 0.0 1.8 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) BUD22 PF09073.10 RLN65661.1 - 0.032 13.6 16.1 0.038 13.3 16.1 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 RLN65661.1 - 9.6 4.2 27.4 13 3.7 27.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi HMA PF00403.26 RLN65662.1 - 5.4e-72 238.1 26.6 1.4e-14 54.2 0.4 7.9 8 0 0 8 8 8 6 Heavy-metal-associated domain Hydrolase PF00702.26 RLN65662.1 - 1.4e-47 162.7 0.2 3.1e-47 161.6 0.2 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RLN65662.1 - 1.3e-44 151.9 4.3 2.3e-44 151.1 1.5 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RLN65662.1 - 1.2e-05 25.2 0.5 0.0098 15.7 0.3 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Fer2_BFD PF04324.15 RLN65662.1 - 1 9.7 8.6 2.1e+02 2.3 0.0 5.7 5 0 0 5 5 5 0 BFD-like [2Fe-2S] binding domain Mfa1 PF17445.2 RLN65664.1 - 0.48 10.5 2.3 0.97 9.5 2.3 1.4 1 0 0 1 1 1 0 Mating factor A1 Proteasom_PSMB PF10508.9 RLN65665.1 - 8.5e-18 64.1 0.5 9.3e-16 57.4 0.1 2.8 2 1 0 2 2 2 2 Proteasome non-ATPase 26S subunit FHA PF00498.26 RLN65665.1 - 2e-12 47.3 0.0 3.9e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RLN65665.1 - 0.00014 22.1 0.0 0.00036 20.8 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain COesterase PF00135.28 RLN65708.1 - 1.7e-05 23.9 0.4 2.3e-05 23.5 0.4 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RLN65708.1 - 0.0084 16.0 0.1 0.012 15.5 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold VWA_2 PF13519.6 RLN65709.1 - 2.7e-08 34.4 0.0 2.5e-07 31.3 0.0 2.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 RLN65709.1 - 6.6e-08 33.0 0.0 2.6e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain DNA_pol3_delta2 PF13177.6 RLN65709.1 - 7.8e-06 25.8 0.0 2.1e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase III, delta subunit VPS13_C PF16909.5 RLN65709.1 - 5.6e-05 23.0 0.1 0.00013 21.9 0.1 1.5 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal GBP PF02263.19 RLN65709.1 - 7.9e-05 22.0 0.1 0.00038 19.8 0.2 2.0 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain RHD3 PF05879.12 RLN65709.1 - 0.00011 20.5 0.1 0.00019 19.7 0.1 1.3 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Rad17 PF03215.15 RLN65709.1 - 0.0013 18.7 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 RLN65709.1 - 0.0032 17.9 1.6 0.017 15.5 0.1 3.1 4 0 0 4 4 2 1 AAA ATPase domain AAA PF00004.29 RLN65709.1 - 0.0053 17.2 0.0 0.015 15.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN65709.1 - 0.007 16.6 0.2 0.081 13.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain Rep_fac_C PF08542.11 RLN65709.1 - 0.017 15.5 0.0 0.042 14.3 0.0 1.7 1 0 0 1 1 1 0 Replication factor C C-terminal domain AAA_24 PF13479.6 RLN65709.1 - 0.028 14.1 0.0 1.2 8.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 RLN65709.1 - 0.059 13.4 0.0 0.059 13.4 0.0 1.8 2 0 0 2 2 1 0 Dynamin family MMR_HSR1 PF01926.23 RLN65709.1 - 0.074 13.1 0.0 0.24 11.5 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase Chorein_N PF12624.7 RLN65710.1 - 4.3e-13 49.4 3.1 3.5e-11 43.2 1.0 2.7 2 1 0 2 2 2 1 N-terminal region of Chorein or VPS13 Fmp27 PF10344.9 RLN65710.1 - 0.019 13.1 0.0 0.021 12.9 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 VPS13 PF16908.5 RLN65710.1 - 0.042 13.7 0.2 0.063 13.1 0.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting-associated protein 13, N-terminal Hist_deacetyl PF00850.19 RLN65711.1 - 7.7e-11 42.0 0.0 8.6e-11 41.9 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Pkinase PF00069.25 RLN65713.1 - 1.2e-57 195.3 0.0 1.7e-57 194.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN65713.1 - 6e-29 101.1 0.0 1.8e-28 99.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN65713.1 - 0.0026 17.1 0.0 0.0048 16.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN65713.1 - 0.0065 16.4 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN65713.1 - 0.019 14.3 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SPX PF03105.19 RLN65713.1 - 0.1 12.5 5.4 3.4 7.5 0.3 2.2 2 0 0 2 2 2 0 SPX domain Choline_kinase PF01633.20 RLN65713.1 - 0.17 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 RLN65714.1 - 1.3e-49 169.0 0.0 1.5e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN65714.1 - 4.4e-33 114.7 0.0 5.4e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN65714.1 - 4.9e-07 29.4 0.0 6.7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RLN65714.1 - 1.1e-06 27.7 0.0 1.6e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 RLN65714.1 - 0.0053 16.1 0.0 0.0085 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN65714.1 - 0.0057 16.6 0.5 1.1 9.2 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family NAP PF00956.18 RLN65715.1 - 8.2e-63 212.1 0.7 1.2e-62 211.5 0.7 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Muted PF14942.6 RLN65715.1 - 0.02 15.2 4.6 0.027 14.8 3.5 1.7 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Latrophilin PF02354.16 RLN65715.1 - 0.14 11.2 0.4 0.15 11.1 0.4 1.3 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region Bap31 PF05529.12 RLN65715.1 - 0.22 11.4 0.1 0.36 10.7 0.1 1.3 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region NAP PF00956.18 RLN65716.1 - 2.7e-06 26.8 1.1 2.9e-06 26.7 0.0 1.5 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) PTPRCAP PF15713.5 RLN65716.1 - 0.013 15.8 2.8 0.013 15.7 2.8 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CENP-B_dimeris PF09026.10 RLN65716.1 - 0.028 14.8 9.1 0.039 14.3 9.1 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.13 RLN65716.1 - 0.062 13.2 1.6 0.063 13.1 1.6 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region GEN1_C PF18380.1 RLN65716.1 - 0.069 14.0 1.1 0.093 13.6 1.1 1.1 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain YL1 PF05764.13 RLN65716.1 - 0.11 12.6 4.5 0.11 12.6 4.5 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Importin_rep_4 PF18808.1 RLN65716.1 - 0.16 12.3 1.3 0.22 11.8 1.3 1.2 1 0 0 1 1 1 0 Importin repeat CDC45 PF02724.14 RLN65716.1 - 0.45 8.7 2.4 0.4 8.9 2.4 1.0 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 RLN65716.1 - 0.55 10.6 10.5 0.86 10.0 10.5 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 RLN65716.1 - 1.9 7.7 6.9 2.3 7.5 6.9 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 RLN65716.1 - 3.7 5.6 7.6 4 5.4 7.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi PX PF00787.24 RLN65721.1 - 0.0055 16.7 0.2 0.014 15.4 0.2 1.9 1 1 0 1 1 1 1 PX domain Aa_trans PF01490.18 RLN65723.1 - 9.1e-40 136.6 18.4 1.4e-39 136.0 18.4 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Mlo PF03094.15 RLN65725.1 - 3.7e-06 25.6 2.2 0.0044 15.5 0.1 2.6 2 1 0 2 2 2 2 Mlo family Glyco_hydro_88 PF07470.13 RLN65725.1 - 0.071 12.2 0.2 0.56 9.2 0.1 2.4 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 FAM167 PF11652.8 RLN65725.1 - 0.086 13.3 0.2 0.24 11.9 0.2 1.8 1 0 0 1 1 1 0 FAM167 DUF16 PF01519.16 RLN65725.1 - 0.13 12.8 0.5 0.36 11.3 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF16 ATG16 PF08614.11 RLN65778.1 - 0.014 15.6 2.9 0.017 15.4 2.9 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Peptidase_S58 PF03576.14 RLN65778.1 - 0.017 14.7 0.1 0.021 14.4 0.1 1.2 1 0 0 1 1 1 0 Peptidase family S58 ZapB PF06005.12 RLN65778.1 - 0.076 13.5 1.3 0.15 12.5 1.3 1.5 1 0 0 1 1 1 0 Cell division protein ZapB SLAM PF06214.11 RLN65778.1 - 0.14 12.2 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Signaling lymphocytic activation molecule (SLAM) protein DDE_1 PF03184.19 RLN65779.1 - 3.2e-30 105.1 0.0 4.8e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN65779.1 - 4.9e-06 26.5 1.2 1e-05 25.5 0.1 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 RLN65779.1 - 1.7e-05 24.5 2.3 5.1e-05 22.9 0.1 2.6 3 0 0 3 3 3 1 Fission yeast centromere protein N-terminal domain Gar1 PF04410.14 RLN65780.1 - 7.2e-33 113.6 0.0 7.2e-33 113.6 0.0 1.9 2 1 0 2 2 2 1 Gar1/Naf1 RNA binding region ALMT PF11744.8 RLN65780.1 - 0.15 10.9 2.9 0.21 10.4 2.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DNA_pol_phi PF04931.13 RLN65780.1 - 1.2 7.2 14.4 1.8 6.6 14.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Sod_Fe_C PF02777.18 RLN65781.1 - 5e-41 139.0 0.2 1.9e-40 137.1 0.0 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 RLN65781.1 - 2.7e-27 95.1 2.2 4.9e-27 94.2 2.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain UPF0183 PF03676.14 RLN65782.1 - 9.6e-32 110.7 0.0 7.7e-18 65.0 0.0 2.0 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0183) cNMP_binding PF00027.29 RLN65786.1 - 1.1e-10 41.4 0.0 2.1e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN65786.1 - 0.0039 16.4 0.1 0.0039 16.4 0.1 1.5 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 RLN65786.1 - 0.019 14.9 0.3 0.041 13.9 0.3 1.6 1 0 0 1 1 1 0 Ion channel DUF3128 PF11326.8 RLN65786.1 - 0.057 13.8 0.5 10 6.6 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) TMEM192 PF14802.6 RLN65786.1 - 0.25 10.4 1.9 0.52 9.4 1.9 1.4 1 0 0 1 1 1 0 TMEM192 family SET PF00856.28 RLN65811.1 - 5.8e-13 49.6 6.4 1.8e-12 48.0 1.2 2.4 1 1 1 2 2 2 1 SET domain EAP30 PF04157.16 RLN65811.1 - 0.011 15.1 1.3 2.4 7.4 0.0 2.4 3 0 0 3 3 3 0 EAP30/Vps36 family MIF4G_like_2 PF09090.11 RLN65811.1 - 0.028 13.9 0.3 0.028 13.9 0.3 1.6 2 0 0 2 2 2 0 MIF4G like DUF1840 PF08895.11 RLN65811.1 - 0.18 12.1 0.6 0.4 11.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) zf-MYND PF01753.18 RLN65811.1 - 7.4 6.8 12.9 0.05 13.7 4.0 2.0 2 0 0 2 2 2 0 MYND finger PX PF00787.24 RLN65821.1 - 0.00071 19.5 0.4 0.0022 17.9 0.4 1.8 1 1 0 1 1 1 1 PX domain SR-25 PF10500.9 RLN65823.1 - 0.18 11.4 15.4 0.25 10.9 15.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAM220 PF15487.6 RLN65823.1 - 1.3 8.6 5.9 1.8 8.1 5.9 1.2 1 0 0 1 1 1 0 FAM220 family Mitofilin PF09731.9 RLN65823.1 - 2.7 6.7 11.4 3.3 6.4 11.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PH PF00169.29 RLN65824.1 - 2e-67 224.3 1.8 9.4e-13 48.6 0.0 7.3 6 1 0 6 6 6 6 PH domain PH_8 PF15409.6 RLN65824.1 - 7.7e-24 83.8 0.1 0.00014 22.1 0.0 6.4 6 0 0 6 6 6 6 Pleckstrin homology domain PH_11 PF15413.6 RLN65824.1 - 3.8e-16 59.4 20.1 0.032 14.6 0.0 8.1 6 4 2 8 8 8 6 Pleckstrin homology domain PH_9 PF15410.6 RLN65824.1 - 0.00045 20.6 0.8 52 4.2 0.0 6.2 7 1 1 8 8 8 0 Pleckstrin homology domain Retrotran_gag_3 PF14244.6 RLN65824.1 - 0.11 12.3 2.5 12 5.8 0.2 2.7 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type IN_DBD_C PF00552.21 RLN65824.1 - 0.14 11.4 0.6 0.41 10.0 0.1 2.1 2 0 0 2 2 2 0 Integrase DNA binding domain Secretin_N PF03958.17 RLN65824.1 - 0.16 12.4 2.2 19 5.7 0.0 4.3 4 0 0 4 4 4 0 Bacterial type II/III secretion system short domain DUF4219 PF13961.6 RLN65824.1 - 2.1 8.1 4.8 5.7 6.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) GlcNAc PF11397.8 RLN65825.1 - 4.3e-46 158.0 0.1 2e-42 146.0 0.1 2.5 1 1 0 1 1 1 1 Glycosyltransferase (GlcNAc) PCI PF01399.27 RLN65825.1 - 1.2e-12 48.3 0.3 3.3e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 PCI domain Tubulin PF00091.25 RLN65832.1 - 3.5e-65 219.9 0.0 4.1e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 RLN65832.1 - 0.0051 16.5 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Cupin_8 PF13621.6 RLN65834.1 - 2.7e-21 76.5 0.0 2.2e-13 50.5 0.0 2.3 2 0 0 2 2 2 2 Cupin-like domain JmjC PF02373.22 RLN65834.1 - 9.1e-14 51.9 0.0 2.5e-13 50.4 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Leader_Trp PF08255.11 RLN65834.1 - 0.1 12.6 0.2 0.33 11.0 0.2 1.9 1 0 0 1 1 1 0 Trp-operon Leader Peptide Thiolase_N PF00108.23 RLN65835.1 - 5.8e-81 271.7 3.3 8.9e-81 271.1 3.3 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RLN65835.1 - 9.4e-49 164.2 0.1 2.1e-48 163.1 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 RLN65835.1 - 0.034 14.3 0.8 0.16 12.2 0.0 2.6 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 RLN65835.1 - 0.057 13.0 2.1 0.23 11.0 0.7 2.4 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 RLN65835.1 - 0.13 12.1 2.0 15 5.5 0.7 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HA PF03457.14 RLN65837.1 - 8.1e-22 77.3 5.4 0.00029 21.1 0.0 5.4 5 0 0 5 5 5 4 Helicase associated domain Adhes-Ig_like PF09085.10 RLN65837.1 - 0.052 13.7 0.0 0.052 13.7 0.0 2.5 2 1 1 3 3 3 0 Adhesion molecule, immunoglobulin-like Asp-B-Hydro_N PF05279.11 RLN65837.1 - 5 7.1 11.7 9.8 6.2 11.7 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Peptidase_M24 PF00557.24 RLN65838.1 - 2.9e-52 177.4 0.3 4.4e-52 176.8 0.3 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 RLN65838.1 - 7.1e-28 96.8 0.2 4.8e-27 94.1 0.1 2.2 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Peptidase_M24 PF00557.24 RLN65839.1 - 3.1e-52 177.3 0.2 5e-52 176.6 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 RLN65839.1 - 1.1e-27 96.2 0.2 8.3e-27 93.4 0.1 2.2 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain COesterase PF00135.28 RLN65885.1 - 1.4e-92 311.2 0.0 1.8e-92 310.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RLN65885.1 - 7.2e-06 26.0 0.9 0.007 16.2 0.2 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN65885.1 - 0.039 13.4 0.7 0.07 12.6 0.7 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family SKN1 PF03935.15 RLN65935.1 - 3.9e-33 114.6 10.2 5.2e-30 104.3 10.1 3.3 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Nodulin_late PF07127.11 RLN65935.1 - 2.2 8.7 4.9 8.8 6.8 0.2 3.2 3 0 0 3 3 3 0 Late nodulin protein DUF2551 PF10826.8 RLN65936.1 - 0.1 12.8 0.1 0.46 10.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2551) CENP-K PF11802.8 RLN65936.1 - 0.24 10.9 2.1 0.29 10.7 1.4 1.4 1 1 0 1 1 1 0 Centromere-associated protein K CCDC23 PF15674.5 RLN65936.1 - 0.29 11.2 2.3 1.2 9.2 0.6 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 23 Peptidase_M90 PF06167.12 RLN65936.1 - 0.35 10.4 2.1 0.34 10.5 0.6 1.7 2 0 0 2 2 2 0 Glucose-regulated metallo-peptidase M90 OrfB_IS605 PF01385.19 RLN65937.1 - 0.0056 16.9 3.0 0.0056 16.9 3.0 2.2 2 0 0 2 2 2 1 Probable transposase DVL PF08137.12 RLN65937.1 - 0.036 13.9 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 DVL family bZIP_2 PF07716.15 RLN65938.1 - 0.00022 21.2 13.7 0.00056 19.9 8.3 2.5 2 0 0 2 2 2 1 Basic region leucine zipper Med21 PF11221.8 RLN65938.1 - 0.026 14.8 2.7 0.055 13.7 2.7 1.5 1 0 0 1 1 1 0 Subunit 21 of Mediator complex GrpE PF01025.19 RLN65938.1 - 0.24 11.1 2.3 6.5 6.4 0.0 2.4 2 0 0 2 2 2 0 GrpE bZIP_1 PF00170.21 RLN65938.1 - 0.64 10.2 14.9 0.079 13.1 9.5 2.2 2 0 0 2 2 2 0 bZIP transcription factor Peptidase_S74 PF13884.6 RLN65939.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Chaperone of endosialidase CALM_bind PF16025.5 RLN65940.1 - 0.47 11.0 3.1 0.29 11.6 0.3 2.1 2 0 0 2 2 2 0 Calcium-dependent calmodulin binding FlxA PF14282.6 RLN65941.1 - 0.12 12.4 4.7 0.29 11.1 3.6 2.1 1 1 0 1 1 1 0 FlxA-like protein LZ3wCH PF18517.1 RLN65941.1 - 0.21 11.7 1.7 1.5 9.0 0.3 2.6 3 0 0 3 3 3 0 Leucine zipper with capping helix domain MutS_IV PF05190.18 RLN65941.1 - 0.29 11.5 2.7 2.5 8.5 0.6 2.2 1 1 1 2 2 2 0 MutS family domain IV Sec2p PF06428.11 RLN65941.1 - 0.52 10.3 4.1 3.6 7.6 0.5 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF4407 PF14362.6 RLN65941.1 - 0.55 9.5 4.3 0.66 9.3 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 RLN65941.1 - 3.4 8.2 6.6 0.76 10.3 3.0 1.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2408 PF10303.9 RLN65942.1 - 0.082 13.5 1.8 0.16 12.5 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF5082 PF16888.5 RLN65942.1 - 0.086 13.1 0.9 0.2 12.0 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) bZIP_1 PF00170.21 RLN65944.1 - 0.53 10.4 8.7 0.13 12.4 4.7 2.0 2 0 0 2 2 2 0 bZIP transcription factor BHD_3 PF10405.9 RLN65950.1 - 1.7e-22 79.6 0.0 4e-22 78.4 0.0 1.7 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 RLN65950.1 - 2e-19 69.7 0.2 3.9e-19 68.8 0.2 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 RLN65950.1 - 1.4e-16 60.0 0.0 2.4e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 RLN65950.1 - 8.9e-11 42.6 1.3 3.6e-10 40.6 0.0 2.6 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 RLN65950.1 - 0.0012 19.3 0.1 0.0033 17.9 0.1 1.8 1 1 0 1 1 1 1 Transglutaminase-like superfamily Pox_Ag35 PF03286.14 RLN65950.1 - 4.1 7.1 6.8 0.48 10.2 0.1 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RRM_1 PF00076.22 RLN65952.1 - 2.2e-14 53.0 0.0 3.4e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2457 PF10446.9 RLN65952.1 - 2 7.5 13.1 2.8 7.0 13.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Mob_synth_C PF06463.13 RLN65953.1 - 6.8e-37 126.3 0.0 1.5e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 RLN65953.1 - 1e-29 104.0 0.0 1.9e-29 103.2 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 RLN65953.1 - 7.8e-09 35.9 0.0 2e-08 34.6 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 RLN65953.1 - 0.00018 21.6 0.0 0.00038 20.6 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain CEP44 PF15007.6 RLN65955.1 - 6.7e-29 100.6 0.1 1.3e-28 99.7 0.1 1.5 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 HSBP1 PF06825.12 RLN65955.1 - 0.16 11.8 0.2 3.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Heat shock factor binding protein 1 UNC-50 PF05216.13 RLN65998.1 - 6.9e-57 192.5 18.3 7.9e-48 162.9 8.8 2.0 2 0 0 2 2 2 2 UNC-50 family PAE PF03283.13 RLN65999.1 - 2.4e-11 43.4 0.0 4.6e-11 42.4 0.0 1.5 1 1 0 1 1 1 1 Pectinacetylesterase DUF2235 PF09994.9 RLN65999.1 - 0.026 13.9 0.0 0.066 12.6 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) POB3_N PF17292.2 RLN66000.1 - 9.9e-09 35.5 0.0 1.3e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 POB3-like N-terminal PH domain PH_TFIIH PF08567.11 RLN66000.1 - 0.085 13.2 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain RrnaAD PF00398.20 RLN66002.1 - 1.1e-58 198.5 0.0 1.4e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 RLN66002.1 - 5e-09 36.7 0.0 1.1e-08 35.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN66002.1 - 2.5e-08 34.5 0.0 5.9e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN66002.1 - 0.00012 22.7 0.0 0.00027 21.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 RLN66002.1 - 0.00018 21.0 0.0 0.00033 20.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase NodS PF05401.11 RLN66002.1 - 0.00019 21.1 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_23 PF13489.6 RLN66002.1 - 0.00028 20.7 0.0 0.00047 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 RLN66002.1 - 0.0004 20.2 0.1 0.00066 19.5 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 RLN66002.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PRMT5 PF05185.16 RLN66002.1 - 0.0017 18.3 2.1 0.0053 16.6 0.0 2.4 3 0 0 3 3 3 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.16 RLN66002.1 - 0.0017 18.1 0.1 0.0028 17.4 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 RLN66002.1 - 0.0043 16.8 0.0 0.0088 15.7 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 RLN66002.1 - 0.0052 16.6 0.0 0.0078 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN66002.1 - 0.0064 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 RLN66002.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_28 PF02636.17 RLN66002.1 - 0.023 14.3 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 RLN66002.1 - 0.034 13.4 0.0 0.077 12.3 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase domain tRNA_U5-meth_tr PF05958.11 RLN66002.1 - 0.076 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_18 PF12847.7 RLN66002.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DEAD PF00270.29 RLN66056.1 - 3.8e-06 26.8 0.4 0.014 15.2 0.1 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN66056.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.8 1 1 0 1 1 1 0 Helicase conserved C-terminal domain CBS PF00571.28 RLN66056.1 - 0.057 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 CBS domain Elicitin PF00964.17 RLN66057.1 - 5.9e-75 247.4 31.4 1.2e-20 73.4 0.6 4.3 4 0 0 4 4 4 4 Elicitin NNMT_PNMT_TEMT PF01234.17 RLN66057.1 - 0.036 13.2 4.7 2.2 7.4 0.4 2.2 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Dynamin_N PF00350.23 RLN66058.1 - 0.078 13.0 1.5 0.078 13.0 1.5 1.6 2 0 0 2 2 2 0 Dynamin family DUF3043 PF11241.8 RLN66058.1 - 1.1 9.2 4.2 1.5 8.8 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) MscS_TM PF12794.7 RLN66058.1 - 4.3 6.1 6.2 5.8 5.7 6.2 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Elicitin PF00964.17 RLN66059.1 - 5.9e-22 77.6 1.4 5.9e-22 77.6 1.4 2.1 2 0 0 2 2 2 1 Elicitin PP_M1 PF03012.14 RLN66059.1 - 1.7 8.1 3.7 2.2 7.8 3.7 1.1 1 0 0 1 1 1 0 Phosphoprotein Herpes_pp85 PF04637.12 RLN66059.1 - 2 6.7 8.4 2.9 6.2 8.4 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Hamartin PF04388.12 RLN66059.1 - 6.4 5.3 11.2 7.5 5.1 11.2 1.0 1 0 0 1 1 1 0 Hamartin protein Peptidase_C13 PF01650.18 RLN66059.1 - 7.2 6.0 8.1 0.51 9.8 1.3 2.0 2 0 0 2 2 2 0 Peptidase C13 family Elicitin PF00964.17 RLN66060.1 - 4e-21 74.9 1.0 4e-21 74.9 1.0 2.1 2 0 0 2 2 2 1 Elicitin DUF4179 PF13786.6 RLN66060.1 - 0.43 11.1 3.6 1.2 9.6 3.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) Herpes_pp85 PF04637.12 RLN66060.1 - 5.3 5.3 7.5 7.5 4.8 7.5 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Elicitin PF00964.17 RLN66061.1 - 2.7e-20 72.2 4.2 3.5e-20 71.9 2.6 1.9 1 1 1 2 2 2 2 Elicitin Elicitin PF00964.17 RLN66062.1 - 3.5e-20 71.9 2.3 5.7e-20 71.2 1.8 1.6 1 1 0 1 1 1 1 Elicitin Nup160 PF11715.8 RLN66068.1 - 6.3e-18 64.7 0.0 3.7e-17 62.2 0.0 2.0 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Ank_2 PF12796.7 RLN66105.1 - 4.1e-09 36.9 0.0 2.8e-08 34.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN66105.1 - 7.9e-08 32.0 0.0 0.015 15.8 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 RLN66105.1 - 9.6e-08 32.4 0.1 0.037 14.6 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN66105.1 - 4.9e-05 23.6 0.1 0.0079 16.6 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 RLN66105.1 - 0.00011 22.4 0.2 0.034 14.5 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ndc1_Nup PF09531.10 RLN66105.1 - 5.1 5.7 8.7 6.1 5.4 8.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hid1 PF12722.7 RLN66105.1 - 6.2 4.8 7.0 7.4 4.6 7.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ABC_tran PF00005.27 RLN66107.1 - 3e-30 105.5 0.0 4.9e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 RLN66107.1 - 1e-14 54.9 0.0 1.3e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 RLN66107.1 - 6.3e-08 32.3 0.0 4.7e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RLN66107.1 - 8e-05 23.1 0.4 0.00036 21.0 0.4 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RLN66107.1 - 0.00024 21.4 0.0 0.31 11.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 RLN66107.1 - 0.0033 17.4 0.0 0.013 15.5 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain IstB_IS21 PF01695.17 RLN66107.1 - 0.0052 16.5 0.0 0.4 10.4 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ABC_ATPase PF09818.9 RLN66107.1 - 0.0057 15.5 0.0 0.012 14.5 0.0 1.4 1 1 0 1 1 1 1 Predicted ATPase of the ABC class AAA PF00004.29 RLN66107.1 - 0.0072 16.7 0.4 2.6 8.5 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 RLN66107.1 - 0.0084 15.7 0.0 0.48 10.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RLN66107.1 - 0.0095 15.7 0.4 0.11 12.2 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 RLN66107.1 - 0.016 15.2 0.1 0.14 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 RLN66107.1 - 0.017 14.8 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 RLN66107.1 - 0.022 15.0 0.3 0.3 11.4 0.3 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 RLN66107.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 RLN66107.1 - 0.15 11.9 0.1 7 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF421 PF04239.12 RLN66108.1 - 0.013 15.3 1.7 0.013 15.3 1.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF421) Fez1 PF06818.15 RLN66108.1 - 0.015 15.8 15.6 0.3 11.5 0.9 2.3 2 0 0 2 2 2 0 Fez1 UPF0242 PF06785.11 RLN66108.1 - 0.096 12.8 15.5 0.049 13.7 5.6 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Cob_adeno_trans PF01923.18 RLN66108.1 - 0.21 11.7 8.4 0.5 10.5 2.6 3.1 3 1 0 3 3 3 0 Cobalamin adenosyltransferase EMP24_GP25L PF01105.24 RLN66108.1 - 0.5 10.3 0.1 0.5 10.3 0.1 2.7 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD ERM PF00769.19 RLN66108.1 - 0.56 10.0 18.3 3.5 7.4 12.0 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Suppressor_APC PF11414.8 RLN66108.1 - 0.76 9.9 14.5 0.34 11.0 0.9 3.6 2 1 1 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein DUF2451 PF10474.9 RLN66108.1 - 0.99 9.1 6.1 0.2 11.4 2.0 1.8 2 1 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) DUF5623 PF18536.1 RLN66108.1 - 2.5 8.4 6.3 8.4 6.7 6.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5623) Exonuc_VII_L PF02601.15 RLN66108.1 - 2.5 7.6 12.3 7 6.1 6.7 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit TolA_bind_tri PF16331.5 RLN66108.1 - 2.5 8.2 17.1 0.15 12.2 4.1 3.8 4 1 1 5 5 4 0 TolA binding protein trimerisation APG6_N PF17675.1 RLN66108.1 - 2.6 8.6 23.8 3.1 8.3 2.0 3.0 2 1 1 3 3 3 0 Apg6 coiled-coil region DUF5320 PF17253.2 RLN66108.1 - 3.1 8.9 5.3 22 6.2 1.1 3.1 2 1 0 2 2 2 0 Family of unknown function (DUF5320) Ax_dynein_light PF10211.9 RLN66108.1 - 5.1 7.0 17.2 0.94 9.4 9.4 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain V_ATPase_I PF01496.19 RLN66108.1 - 6.5 4.5 10.2 2.5 5.9 4.3 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family NBP1 PF08537.10 RLN66108.1 - 7.9 5.8 13.1 8 5.8 0.2 2.4 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 GAS PF13851.6 RLN66108.1 - 8 5.8 22.6 8.4 5.7 12.8 2.7 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.22 RLN66108.1 - 8.9 6.6 16.3 7.3 6.9 6.4 2.9 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain SPRY PF00622.28 RLN66109.1 - 3.9e-08 33.4 0.0 1.1e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 SPRY domain Exonuc_VII_L PF02601.15 RLN66109.1 - 1.5 8.3 9.8 3.1 7.3 9.8 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Exo_endo_phos PF03372.23 RLN66110.1 - 3.4e-11 43.1 0.1 6.3e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M56 PF05569.11 RLN66110.1 - 0.14 11.3 3.8 0.43 9.7 0.0 2.1 2 0 0 2 2 2 0 BlaR1 peptidase M56 2TM PF13239.6 RLN66110.1 - 0.18 12.1 1.2 0.35 11.2 1.2 1.4 1 0 0 1 1 1 0 2TM domain DUF733 PF05306.11 RLN66113.1 - 0.014 15.7 0.1 0.014 15.7 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF733) DAHP_synth_2 PF01474.16 RLN66113.1 - 0.075 11.5 1.1 0.11 11.0 1.1 1.2 1 0 0 1 1 1 0 Class-II DAHP synthetase family TFIIA PF03153.13 RLN66113.1 - 0.21 11.6 7.6 0.31 11.0 7.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 RLN66113.1 - 0.26 9.9 6.2 0.35 9.5 6.2 1.2 1 0 0 1 1 1 0 Hamartin protein bZIP_2 PF07716.15 RLN66113.1 - 4 7.6 14.3 0.13 12.4 4.6 2.6 2 0 0 2 2 2 0 Basic region leucine zipper Macoilin PF09726.9 RLN66113.1 - 4.2 5.8 10.5 6.4 5.2 10.5 1.2 1 0 0 1 1 1 0 Macoilin family MULE PF10551.9 RLN66115.1 - 4.8e-12 46.1 0.1 1.3e-11 44.7 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 RLN66115.1 - 0.021 15.5 0.1 0.054 14.2 0.1 1.7 1 0 0 1 1 1 0 FAR1 DNA-binding domain Paf1 PF03985.13 RLN66115.1 - 2.3 7.2 3.9 3.6 6.5 3.9 1.2 1 0 0 1 1 1 0 Paf1 DDE_Tnp_1_7 PF13843.6 RLN66116.1 - 6.6e-22 78.3 0.1 8.6e-22 77.9 0.1 1.2 1 0 0 1 1 1 1 Transposase IS4 FAM163 PF15069.6 RLN66117.1 - 0.00041 20.8 0.0 0.00057 20.4 0.0 1.3 1 0 0 1 1 1 1 FAM163 family PELOTA_1 PF15608.6 RLN66117.1 - 0.051 13.5 0.2 0.088 12.7 0.2 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Tnp_zf-ribbon_2 PF13842.6 RLN66117.1 - 0.21 12.4 5.4 0.4 11.5 5.4 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon FYVE PF01363.21 RLN66119.1 - 2.4e-06 27.6 3.5 4.1e-06 26.8 3.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN66119.1 - 0.01 16.1 2.7 0.021 15.0 2.7 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger BNIP2 PF12496.8 RLN66119.1 - 0.047 14.1 7.5 0.064 13.7 7.5 1.2 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CDC45 PF02724.14 RLN66119.1 - 0.11 10.8 1.4 0.13 10.6 1.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid_p PF12226.8 RLN66119.1 - 0.25 10.4 10.5 0.3 10.2 10.5 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 RLN66119.1 - 1.2 7.2 6.2 1.7 6.8 6.2 1.2 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 RLN66119.1 - 4.4 7.1 8.5 5.7 6.8 8.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Pkinase PF00069.25 RLN66155.1 - 1.4e-50 172.2 0.0 3.6e-50 170.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN66155.1 - 4.2e-46 157.3 0.0 1.1e-45 156.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN66155.1 - 0.00062 19.8 1.0 0.047 13.6 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family FAM176 PF14851.6 RLN66155.1 - 0.017 14.8 0.1 0.05 13.3 0.1 1.8 1 0 0 1 1 1 0 FAM176 family Pkinase_fungal PF17667.1 RLN66155.1 - 0.038 12.8 0.0 0.078 11.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase TGase_elicitor PF16683.5 RLN66156.1 - 1.7e-05 23.8 0.0 2.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Transglutaminase elicitor DUF3951 PF13131.6 RLN66160.1 - 0.24 11.6 3.1 0.29 11.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) Sec7_N PF12783.7 RLN66166.1 - 9.2 6.1 7.2 6.9 6.6 0.6 3.9 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal GAF PF01590.26 RLN66167.1 - 2.5e-24 86.4 0.1 2.5e-07 31.4 0.0 3.4 3 0 0 3 3 3 3 GAF domain GAF_2 PF13185.6 RLN66167.1 - 2e-13 50.8 0.1 0.00042 20.6 0.1 3.8 3 0 0 3 3 3 3 GAF domain GAF_3 PF13492.6 RLN66167.1 - 0.00086 19.6 0.0 0.58 10.5 0.0 4.2 5 0 0 5 5 5 1 GAF domain peroxidase PF00141.23 RLN66168.1 - 9.1e-39 133.5 0.0 1.6e-38 132.7 0.0 1.4 1 1 0 1 1 1 1 Peroxidase CRT-like PF08627.10 RLN66169.1 - 1.7e-48 165.3 5.9 2e-48 165.1 5.9 1.1 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 RLN66169.1 - 1.2e-05 25.0 0.3 1.2e-05 25.0 0.3 2.1 2 0 0 2 2 2 1 Solute carrier family 35 Nuc_sug_transp PF04142.15 RLN66169.1 - 0.0051 16.0 0.8 0.052 12.7 0.1 2.0 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.20 RLN66169.1 - 0.066 13.4 0.3 0.066 13.4 0.3 2.8 3 1 0 3 3 3 0 EamA-like transporter family IQCJ-SCHIP1 PF15157.6 RLN66169.1 - 0.18 11.6 0.1 0.29 11.0 0.1 1.2 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Arm PF00514.23 RLN66218.1 - 5e-18 64.5 0.1 0.0011 19.0 0.0 5.5 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 RLN66218.1 - 0.0026 18.2 4.3 4.1 8.4 0.1 4.6 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat HEAT PF02985.22 RLN66218.1 - 0.0043 17.2 0.1 14 6.2 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 RLN66218.1 - 0.0075 16.8 2.7 1.9 9.1 0.0 4.2 4 0 0 4 4 4 1 HEAT-like repeat Wap1 PF16997.5 RLN66218.1 - 0.017 14.3 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Wap1 domain MORN PF02493.20 RLN66219.1 - 5.6e-09 35.4 35.8 0.09 12.7 0.3 8.7 8 1 0 8 8 8 6 MORN repeat FapA PF03961.13 RLN66219.1 - 0.2 10.2 0.0 0.38 9.3 0.0 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Ribosomal_S17_N PF16205.5 RLN66220.1 - 4.6e-30 103.8 1.0 4.6e-30 103.8 1.0 1.6 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 RLN66220.1 - 4.5e-26 90.7 0.9 4.5e-26 90.7 0.9 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 NADH-u_ox-rdase PF10785.9 RLN66220.1 - 2.9e-21 76.0 0.1 4.9e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF5487 PF17589.2 RLN66220.1 - 0.2 12.0 0.0 0.36 11.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5487) Roc PF08477.13 RLN66221.1 - 1.3e-05 25.4 0.0 0.0027 17.9 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RLN66221.1 - 3.1e-05 23.6 0.0 0.00099 18.7 0.0 2.3 2 1 0 2 2 2 2 Ras family zf-CSL PF05207.13 RLN66222.1 - 6.9e-24 83.4 1.2 1.1e-23 82.7 1.2 1.3 1 0 0 1 1 1 1 CSL zinc finger Kinesin PF00225.23 RLN66223.1 - 4.3e-100 334.9 0.8 1.1e-99 333.5 0.8 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN66223.1 - 7.7e-17 61.6 0.0 3e-16 59.7 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding VPS38 PF17649.1 RLN66223.1 - 0.07 12.0 15.0 0.049 12.5 0.7 2.5 2 1 0 2 2 2 0 Vacuolar protein sorting 38 GAS PF13851.6 RLN66223.1 - 0.12 11.7 40.2 0.14 11.5 15.9 3.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding MSA-2c PF12238.8 RLN66223.1 - 0.71 9.8 3.7 0.59 10.1 1.3 2.1 1 1 0 1 1 1 0 Merozoite surface antigen 2c Jnk-SapK_ap_N PF09744.9 RLN66223.1 - 1.6 9.0 45.8 2.3 8.4 17.0 3.7 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DUF3037 PF11236.8 RLN66223.1 - 4 7.9 7.8 1.4 9.3 0.5 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3037) DUF948 PF06103.11 RLN66223.1 - 5.1 7.4 10.2 15 5.9 0.1 4.2 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 RLN66223.1 - 7.2 6.8 25.2 1.6 8.9 3.9 4.4 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Methyltransf_16 PF10294.9 RLN66224.1 - 4.4e-14 52.6 0.0 5.9e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_11 PF08241.12 RLN66224.1 - 0.029 15.0 0.0 0.051 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain VWA_2 PF13519.6 RLN66225.1 - 5.2e-15 56.0 0.0 6.2e-15 55.8 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 RLN66225.1 - 0.00073 19.4 0.0 0.00083 19.2 0.0 1.0 1 0 0 1 1 1 1 Ssl1-like AhpC-TSA PF00578.21 RLN66226.1 - 3e-79 263.0 0.0 6.6e-19 68.1 0.0 4.2 4 0 0 4 4 4 4 AhpC/TSA family Redoxin PF08534.10 RLN66226.1 - 1.6e-43 148.0 0.2 1.9e-10 40.6 0.1 4.2 4 0 0 4 4 4 4 Redoxin DUF899 PF05988.12 RLN66226.1 - 9.4e-07 28.6 0.0 0.24 10.9 0.0 3.8 4 1 0 4 4 4 2 Bacterial protein of unknown function (DUF899) AhpC-TSA_2 PF13911.6 RLN66226.1 - 1.2e-06 28.6 0.0 0.48 10.5 0.0 4.4 4 1 0 4 4 4 2 AhpC/TSA antioxidant enzyme Surp PF01805.20 RLN66226.1 - 0.081 12.9 1.9 47 4.1 0.0 3.8 4 0 0 4 4 4 0 Surp module KAR9 PF08580.10 RLN66226.1 - 0.23 10.0 2.6 0.31 9.6 0.4 1.9 2 0 0 2 2 2 0 Yeast cortical protein KAR9 Histone_H2A_C PF16211.5 RLN66226.1 - 0.58 9.9 2.6 8.9 6.2 0.3 2.6 2 0 0 2 2 2 0 C-terminus of histone H2A Peptidase_C1 PF00112.23 RLN66227.1 - 3.9e-38 131.7 3.1 4.2e-31 108.7 0.5 2.7 1 1 1 2 2 2 2 Papain family cysteine protease Inhibitor_I29 PF08246.12 RLN66227.1 - 0.13 12.7 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) Terminase_1 PF03354.15 RLN66228.1 - 0.15 10.6 0.0 0.17 10.4 0.0 1.0 1 0 0 1 1 1 0 Phage Terminase ABC_tran_CTD PF16326.5 RLN66231.1 - 0.026 14.8 0.5 0.063 13.5 0.5 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain Csm1_N PF18504.1 RLN66231.1 - 0.83 10.0 9.8 4.9 7.6 0.4 3.5 3 0 0 3 3 3 0 Csm1 N-terminal domain CCDC-167 PF15188.6 RLN66231.1 - 6.6 7.1 11.1 0.27 11.6 0.4 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 ACT_7 PF13840.6 RLN66232.1 - 3.8e-35 119.5 0.0 5.2e-17 61.4 0.0 2.3 2 0 0 2 2 2 2 ACT domain Castor1_N PF18700.1 RLN66232.1 - 2e-05 24.3 0.5 0.017 14.9 0.1 2.7 2 0 0 2 2 2 2 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain Ammonium_transp PF00909.21 RLN66270.1 - 1.4e-66 224.8 19.0 1.8e-66 224.5 19.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Corona_M PF01635.18 RLN66270.1 - 0.017 14.4 0.2 0.017 14.4 0.2 2.1 2 1 0 2 2 2 0 Coronavirus M matrix/glycoprotein RACo_C_ter PF14574.6 RLN66270.1 - 0.058 12.4 0.8 0.11 11.6 0.8 1.3 1 0 0 1 1 1 0 C-terminal domain of RACo the ASKHA domain DUF3796 PF12676.7 RLN66270.1 - 0.61 10.5 9.1 0.038 14.4 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) DTW PF03942.15 RLN66274.1 - 1.5e-42 145.6 0.3 2e-42 145.2 0.3 1.2 1 0 0 1 1 1 1 DTW domain Ribo_biogen_C PF04034.13 RLN66274.1 - 0.13 12.0 0.3 7.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Ribosome biogenesis protein, C-terminal S19 PF06756.11 RLN66275.1 - 0.047 13.6 0.3 0.052 13.5 0.3 1.2 1 0 0 1 1 1 0 Chorion protein S19 C-terminal Ank_4 PF13637.6 RLN66280.1 - 2.5e-21 75.8 0.4 2.9e-12 46.8 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN66280.1 - 1.2e-20 73.3 0.9 2.7e-07 30.7 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN66280.1 - 7.3e-20 71.4 0.0 1e-12 48.5 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 RLN66280.1 - 2.9e-17 62.3 0.1 0.00013 22.3 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 RLN66280.1 - 3.8e-16 57.5 0.1 0.00047 20.4 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat F-box-like PF12937.7 RLN66280.1 - 1.7e-06 27.8 0.4 4e-06 26.6 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RLN66280.1 - 0.00017 21.3 0.3 0.00038 20.3 0.3 1.5 1 0 0 1 1 1 1 F-box domain Complex1_LYR PF05347.15 RLN66281.1 - 0.00038 20.5 0.2 0.00065 19.7 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF4490 PF14892.6 RLN66282.1 - 0.0024 17.9 0.1 0.0046 17.0 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4490) Glyco_hydro_43 PF04616.14 RLN66283.1 - 1.6e-32 113.0 0.9 2.3e-32 112.5 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Pec_lyase_C PF00544.19 RLN66284.1 - 1.3e-09 37.9 8.9 5.2e-08 32.7 9.0 2.5 2 1 0 2 2 2 1 Pectate lyase DUF5372 PF17342.2 RLN66284.1 - 0.089 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5372) Glyco_hydro_43 PF04616.14 RLN66285.1 - 1e-34 120.2 5.0 1.5e-34 119.7 5.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 LRR_10 PF18805.1 RLN66285.1 - 0.16 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat Ceramidase PF05875.12 RLN66286.1 - 0.3 10.5 5.3 0.63 9.4 5.3 1.5 1 0 0 1 1 1 0 Ceramidase UPF0182 PF03699.13 RLN66286.1 - 0.3 9.2 1.6 0.4 8.7 1.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Nitroreductase PF00881.24 RLN66287.1 - 5.8e-27 94.8 0.0 1.3e-26 93.6 0.0 1.6 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 RLN66287.1 - 0.0017 17.9 0.0 1.6 8.2 0.0 2.6 2 1 0 2 2 2 2 Putative TM nitroreductase Glyco_hydro_43 PF04616.14 RLN66288.1 - 3.3e-33 115.3 2.0 4.7e-33 114.7 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GAF PF01590.26 RLN66296.1 - 2.6e-14 54.0 0.4 3.7e-07 30.8 0.0 4.0 4 0 0 4 4 4 3 GAF domain GAF_3 PF13492.6 RLN66296.1 - 1e-06 29.1 0.7 0.25 11.7 0.0 4.0 4 0 0 4 4 4 3 GAF domain MFS_1 PF07690.16 RLN66337.1 - 8.4e-29 100.6 23.3 8.4e-29 100.6 23.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily VASt PF16016.5 RLN66346.1 - 1.8e-08 34.9 0.0 0.00032 21.1 0.0 3.5 3 1 0 3 3 3 2 VAD1 Analog of StAR-related lipid transfer domain GRP PF07172.11 RLN66347.1 - 7e-09 36.3 18.4 0.00011 22.8 8.2 2.3 2 0 0 2 2 2 2 Glycine rich protein family Keratin PF02422.16 RLN66347.1 - 3.8 7.3 5.8 2.1 8.1 0.2 2.5 2 0 0 2 2 2 0 Keratin RskA PF10099.9 RLN66347.1 - 4.1 7.7 22.7 0.49 10.7 9.4 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA MarB PF13999.6 RLN66347.1 - 7.2 6.6 9.6 6.4 6.7 2.4 2.2 2 0 0 2 2 2 0 MarB protein LPMO_10 PF03067.15 RLN66348.1 - 1.4e-08 35.6 0.7 2.6e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 RLN66348.1 - 0.0025 17.8 0.4 0.031 14.2 0.3 2.2 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 Sugar_tr PF00083.24 RLN66349.1 - 1.3e-31 110.0 10.8 1.4e-31 109.9 10.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN66349.1 - 3.1e-14 52.7 10.5 3.1e-14 52.7 10.5 1.7 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 RLN66349.1 - 0.0018 16.9 2.9 0.0018 16.9 2.9 1.6 2 0 0 2 2 2 1 MFS/sugar transport protein zf-RNPHF PF08080.12 RLN66349.1 - 0.019 14.9 0.3 0.057 13.4 0.3 1.8 1 0 0 1 1 1 0 RNPHF zinc finger YjcB PF15940.5 RLN66349.1 - 0.022 14.9 0.5 0.043 14.0 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function Transgly_assoc PF04226.13 RLN66349.1 - 0.038 14.2 1.1 0.038 14.2 1.1 2.2 2 0 0 2 2 2 0 Transglycosylase associated protein Sugar_tr PF00083.24 RLN66350.1 - 1.3e-31 110.0 10.8 1.4e-31 109.9 10.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN66350.1 - 3.1e-14 52.7 10.5 3.1e-14 52.7 10.5 1.7 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 RLN66350.1 - 0.0018 16.9 2.9 0.0018 16.9 2.9 1.6 2 0 0 2 2 2 1 MFS/sugar transport protein zf-RNPHF PF08080.12 RLN66350.1 - 0.019 14.9 0.3 0.057 13.4 0.3 1.8 1 0 0 1 1 1 0 RNPHF zinc finger YjcB PF15940.5 RLN66350.1 - 0.022 14.9 0.5 0.043 14.0 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function Transgly_assoc PF04226.13 RLN66350.1 - 0.038 14.2 1.1 0.038 14.2 1.1 2.2 2 0 0 2 2 2 0 Transglycosylase associated protein Ank_4 PF13637.6 RLN66407.1 - 1.2e-37 127.8 13.3 2.3e-05 24.8 0.1 9.7 7 2 3 10 10 10 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN66407.1 - 1.1e-33 114.9 17.7 0.00028 21.1 0.1 13.3 4 2 10 14 14 14 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN66407.1 - 2.5e-33 114.5 5.5 2.7e-07 31.1 0.0 6.3 1 1 8 10 10 10 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN66407.1 - 1.5e-22 77.3 5.1 0.031 14.8 0.0 13.3 12 2 2 14 14 14 3 Ankyrin repeat Ank PF00023.30 RLN66407.1 - 0.00012 22.4 3.5 4.4 7.9 0.0 7.2 7 2 1 8 8 8 1 Ankyrin repeat DUF5049 PF16468.5 RLN66407.1 - 0.00034 20.4 0.0 13 5.8 0.0 6.9 6 2 4 10 10 10 1 Domain of unknown function (DUF5049) DUF4411 PF14367.6 RLN66407.1 - 0.0034 17.3 0.2 7.1 6.5 0.0 4.0 1 1 2 4 4 4 1 Domain of unknown function (DUF4411) DUF3322 PF11795.8 RLN66407.1 - 0.0038 17.3 3.7 1.8 8.5 0.0 5.3 3 2 5 8 8 8 1 Uncharacterized protein conserved in bacteria N-term (DUF3322) TGBp3 PF02495.17 RLN66407.1 - 0.54 9.9 1.6 1.2e+02 2.4 0.0 4.6 6 0 0 6 6 6 0 Triple gene block 3 CD24 PF14984.6 RLN66409.1 - 6.7 7.0 0.0 6.7 7.0 0.0 2.7 2 1 0 2 2 2 0 CD24 protein RNA_pol_A_bac PF01000.26 RLN66419.1 - 1.9e-30 105.5 0.0 3.3e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 RLN66419.1 - 3.4e-24 84.0 0.0 6.3e-24 83.2 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.6 RLN66419.1 - 0.064 13.0 0.3 14 5.6 0.0 2.8 3 0 0 3 3 3 0 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF1242 PF06842.12 RLN66420.1 - 1.2e-17 63.4 1.8 1.8e-17 62.8 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Cytochrom_C1 PF02167.15 RLN66421.1 - 9.1e-91 303.4 0.0 1.1e-90 303.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 RLN66421.1 - 0.00089 19.5 0.0 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 RLN66421.1 - 0.039 15.1 0.0 0.11 13.6 0.0 1.9 1 0 0 1 1 1 0 Cytochrome c Cytomega_UL20A PF05984.12 RLN66422.1 - 1.4 9.2 7.0 3.3 8.1 7.0 1.6 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein Mito_carr PF00153.27 RLN66423.1 - 1.7e-59 197.7 26.4 3.5e-18 65.3 0.1 6.8 6 2 0 6 6 6 6 Mitochondrial carrier protein DUF4514 PF14986.6 RLN66423.1 - 0.014 15.3 0.4 9.9 6.2 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) SatD PF16264.5 RLN66423.1 - 0.016 14.8 0.0 0.86 9.2 0.0 2.2 2 0 0 2 2 2 0 SatD family (SatD) Carb_kinase PF01256.17 RLN66423.1 - 0.064 12.7 0.9 4.1 6.8 0.1 2.4 2 0 0 2 2 2 0 Carbohydrate kinase Parecho_VpG PF06344.11 RLN66423.1 - 2.3 9.0 4.1 1.6e+02 3.3 0.1 4.2 3 0 0 3 3 3 0 Parechovirus Genome-linked protein zf-CCCH_4 PF18044.1 RLN66423.1 - 4.7 7.1 5.1 41 4.1 0.4 2.6 2 0 0 2 2 2 0 CCCH-type zinc finger Pam16 PF03656.13 RLN66424.1 - 1.6e-20 73.4 0.1 2.9e-20 72.6 0.1 1.4 1 0 0 1 1 1 1 Pam16 EF-hand_8 PF13833.6 RLN66424.1 - 1.1e-11 44.4 0.0 5.9e-11 42.1 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN66424.1 - 2.1e-06 26.9 0.6 0.00051 19.4 0.1 3.6 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.6 RLN66424.1 - 6.8e-05 23.2 0.1 0.00055 20.3 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN66424.1 - 0.0017 18.1 0.5 9.3 6.5 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain AzlD PF05437.12 RLN66424.1 - 0.054 13.7 0.1 0.088 13.0 0.1 1.2 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) NUDIX PF00293.28 RLN66425.1 - 2.1e-20 73.1 0.1 3e-20 72.6 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain KxDL PF10241.9 RLN66483.1 - 0.025 14.9 0.9 0.13 12.6 0.2 2.2 2 1 0 2 2 2 0 Uncharacterized conserved protein AIP3 PF03915.13 RLN66483.1 - 0.025 13.7 0.1 0.031 13.4 0.1 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 HR1 PF02185.16 RLN66483.1 - 0.18 11.9 3.9 0.11 12.6 1.5 1.8 2 0 0 2 2 2 0 Hr1 repeat DUF3430 PF11912.8 RLN66484.1 - 3e-08 34.0 25.7 0.0028 17.7 11.1 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3430) Pkinase PF00069.25 RLN66563.1 - 5.9e-48 163.5 0.0 7.7e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN66563.1 - 1e-18 67.6 0.0 2.7e-18 66.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 RLN66563.1 - 0.0032 17.1 0.0 0.0064 16.1 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 RLN66563.1 - 0.031 13.6 0.1 0.056 12.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN66563.1 - 0.23 11.4 5.4 0.8 9.6 0.0 2.8 2 1 0 3 3 3 0 Phosphotransferase enzyme family Peptidase_M3_N PF08439.10 RLN66564.1 - 0.06 13.6 0.2 0.35 11.1 0.1 2.0 2 0 0 2 2 2 0 Oligopeptidase F GRASP55_65 PF04495.14 RLN66564.1 - 0.12 12.7 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Phasin_2 PF09361.10 RLN66565.1 - 0.011 16.0 9.3 1.4 9.2 4.3 3.0 2 1 0 2 2 2 0 Phasin protein LEA_4 PF02987.16 RLN66565.1 - 0.032 14.3 4.9 0.032 14.3 4.9 2.9 4 1 0 4 4 4 0 Late embryogenesis abundant protein Apolipoprotein PF01442.18 RLN66565.1 - 0.43 10.4 20.2 0.097 12.5 0.6 2.8 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain HSP9_HSP12 PF04119.12 RLN66565.1 - 0.57 10.6 4.7 6.6 7.2 0.1 3.0 3 0 0 3 3 3 0 Heat shock protein 9/12 ApoLp-III PF07464.11 RLN66565.1 - 0.58 10.2 3.6 0.42 10.7 0.5 2.3 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) TPR_MLP1_2 PF07926.12 RLN66565.1 - 1.3 9.1 10.9 0.26 11.4 3.8 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein ATP-synt_B PF00430.18 RLN66565.1 - 1.3 9.1 15.6 4.4 7.4 3.9 3.1 3 0 0 3 3 3 0 ATP synthase B/B' CF(0) DUF883 PF05957.13 RLN66565.1 - 6.8 7.4 20.5 2.3 8.9 0.5 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 RLN66565.1 - 9 6.9 16.3 49 4.6 1.8 3.9 2 1 0 2 2 2 0 YtxH-like protein WD40 PF00400.32 RLN66566.1 - 8.6e-05 23.2 13.4 1.1 10.2 0.1 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN66566.1 - 0.0018 18.5 0.0 0.21 11.9 0.0 3.2 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Esterase_phd PF10503.9 RLN66566.1 - 0.01 15.3 0.2 2.1 7.8 0.0 2.7 3 0 0 3 3 3 0 Esterase PHB depolymerase Med6 PF04934.14 RLN66568.1 - 2.7e-35 121.1 0.0 4.5e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component FKBP_C PF00254.28 RLN66569.1 - 3.6e-26 91.3 0.0 4.7e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MtN3_slv PF03083.16 RLN66571.1 - 8e-28 96.3 11.8 2.4e-16 59.5 1.0 3.1 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange Exostosin PF03016.15 RLN66571.1 - 9.7e-06 25.0 0.0 1.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Exostosin family PQ-loop PF04193.14 RLN66571.1 - 0.0041 16.9 6.4 0.52 10.1 2.3 2.9 2 0 0 2 2 2 2 PQ loop repeat LYRIC PF15686.5 RLN66571.1 - 0.77 9.3 4.5 7.9 5.9 0.3 2.2 2 0 0 2 2 2 0 Lysine-rich CEACAM1 co-isolated protein family E1-E2_ATPase PF00122.20 RLN66613.1 - 2.9e-33 114.9 0.0 2.9e-33 114.9 0.0 2.8 3 1 1 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 RLN66613.1 - 1.2e-07 32.2 0.0 3.4e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RLN66613.1 - 0.00023 20.8 0.0 0.00064 19.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 RLN66613.1 - 0.0013 18.8 0.0 0.0027 17.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Intein_splicing PF14890.6 RLN66613.1 - 0.069 13.1 0.0 0.16 11.9 0.0 1.6 1 1 0 1 1 1 0 Intein splicing domain DUF3450 PF11932.8 RLN66670.1 - 0.51 9.6 13.2 0.088 12.1 6.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) YabA PF06156.13 RLN66670.1 - 0.56 10.9 3.2 2.5 8.8 0.1 2.4 2 0 0 2 2 2 0 Initiation control protein YabA Com_YlbF PF06133.11 RLN66670.1 - 1.5 9.5 8.0 6.1 7.5 0.7 2.6 3 0 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA CENP-F_leu_zip PF10473.9 RLN66670.1 - 2.4 8.2 13.6 24 5.0 11.9 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RIH_assoc PF08454.11 RLN66677.1 - 2.8e-22 78.5 0.3 2.8e-22 78.5 0.3 3.8 5 0 0 5 5 5 1 RyR and IP3R Homology associated Ion_trans PF00520.31 RLN66677.1 - 2.1e-16 59.9 6.1 5.7e-16 58.5 6.1 1.7 1 0 0 1 1 1 1 Ion transport protein RYDR_ITPR PF01365.21 RLN66677.1 - 1.7e-13 50.4 0.5 1.3e-12 47.6 0.0 2.8 2 1 1 3 3 3 1 RIH domain Cons_hypoth95 PF03602.15 RLN66677.1 - 0.095 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 UPF0016 PF01169.19 RLN66678.1 - 9.7e-44 147.6 25.9 2.6e-22 78.9 5.8 2.7 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 TerC PF03741.16 RLN66678.1 - 6.6e-05 22.7 0.5 6.6e-05 22.7 0.5 2.1 2 0 0 2 2 2 1 Integral membrane protein TerC family Mntp PF02659.15 RLN66678.1 - 0.0003 20.6 9.6 0.0069 16.2 9.6 2.6 1 1 0 1 1 1 1 Putative manganese efflux pump EF-hand_1 PF00036.32 RLN66678.1 - 0.0014 18.0 0.0 0.0028 17.1 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 RLN66678.1 - 0.0028 17.1 0.0 0.0057 16.1 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 RLN66678.1 - 0.043 13.8 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 RLN66678.1 - 0.073 13.5 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair TBCC PF07986.12 RLN66679.1 - 4.2e-13 49.1 0.0 6.3e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C DUF4694 PF15765.5 RLN66679.1 - 0.055 13.5 0.1 0.086 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4694) PCO_ADO PF07847.12 RLN66680.1 - 6.5e-37 126.9 0.0 1.3e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 PCO_ADO CENP-B_dimeris PF09026.10 RLN66680.1 - 0.013 15.8 11.1 0.033 14.6 11.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Gemini_AL3 PF01407.17 RLN66680.1 - 0.2 11.5 0.0 0.38 10.6 0.0 1.3 1 0 0 1 1 1 0 Geminivirus AL3 protein PI3K_1B_p101 PF10486.9 RLN66680.1 - 0.73 7.5 8.3 1 7.1 8.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Dicty_REP PF05086.12 RLN66680.1 - 3.6 5.4 11.8 5.2 4.9 11.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ANAPC15 PF15243.6 RLN66680.1 - 5.1 7.6 14.3 25 5.4 13.3 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 DNA_pol_phi PF04931.13 RLN66680.1 - 8.9 4.3 18.3 15 3.5 18.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi Elicitin PF00964.17 RLN66681.1 - 0.00013 22.0 0.6 0.00013 22.0 0.6 1.9 2 0 0 2 2 2 1 Elicitin Meth_synt_2 PF01717.18 RLN66682.1 - 2.3e-148 493.8 0.1 8.9e-143 475.4 0.0 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 RLN66682.1 - 2.8e-95 319.4 0.0 8.6e-90 301.4 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain PAN_4 PF14295.6 RLN66721.1 - 2.4e-18 65.8 14.4 8.7e-11 41.6 2.8 3.2 3 0 0 3 3 3 2 PAN domain Cellulase PF00150.18 RLN66721.1 - 2.7e-18 66.4 1.1 3.9e-18 65.9 1.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PAN_1 PF00024.26 RLN66721.1 - 1.8e-16 59.9 3.6 1.2e-07 31.5 0.4 2.6 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 RLN66721.1 - 0.084 13.0 10.0 2.1 8.5 1.5 3.1 3 0 0 3 3 3 0 PAN-like domain Cellulase PF00150.18 RLN66722.1 - 1.4e-19 70.6 0.8 1.9e-19 70.2 0.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PAN_4 PF14295.6 RLN66722.1 - 1.3e-13 50.6 16.4 1.7e-09 37.5 3.9 3.2 3 0 0 3 3 3 2 PAN domain PAN_2 PF08276.11 RLN66722.1 - 0.0024 18.0 10.6 0.34 11.1 1.5 3.2 3 0 0 3 3 3 2 PAN-like domain PP2C PF00481.21 RLN66723.1 - 2.1e-50 171.8 0.0 1.2e-48 166.0 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RLN66723.1 - 5.3e-05 22.9 0.0 0.00027 20.7 0.1 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C PH PF00169.29 RLN66724.1 - 3.5e-12 46.8 0.0 8.4e-11 42.3 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 RLN66724.1 - 1.6e-06 28.5 0.1 3.2e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain ParA PF10609.9 RLN66725.1 - 2.6e-90 302.2 2.2 1.7e-76 256.9 0.4 3.0 1 1 2 3 3 3 3 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 RLN66725.1 - 7.7e-14 51.8 0.0 1.6e-12 47.6 0.0 2.2 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 RLN66725.1 - 1.4e-09 38.2 0.4 2.9e-08 33.8 0.4 2.2 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 RLN66725.1 - 2.2e-07 30.5 0.1 1.1e-06 28.2 0.1 1.9 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 RLN66725.1 - 2.8e-07 30.0 1.1 1.1e-06 28.1 0.4 2.0 1 1 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 RLN66725.1 - 4.2e-05 23.2 0.1 0.0011 18.5 0.1 2.1 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 RLN66725.1 - 6.6e-05 22.6 0.4 0.00016 21.4 0.2 1.7 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 RLN66725.1 - 0.0013 17.7 0.2 0.0022 17.0 0.2 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 RLN66725.1 - 0.0043 17.0 0.1 0.0073 16.2 0.1 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase Fer4_NifH PF00142.18 RLN66725.1 - 0.005 16.3 0.0 0.024 14.1 0.1 1.9 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NACHT PF05729.12 RLN66725.1 - 0.023 14.6 0.6 0.039 13.9 0.6 1.3 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 RLN66725.1 - 0.042 13.6 0.2 0.077 12.7 0.2 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Interfer-bind PF09294.10 RLN66725.1 - 0.06 13.7 0.1 0.096 13.0 0.1 1.3 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III AAA_26 PF13500.6 RLN66725.1 - 0.088 12.6 0.2 7.9 6.2 0.1 2.6 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 RLN66725.1 - 0.09 12.4 0.3 0.25 10.9 0.1 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 RLN66725.1 - 0.1 12.5 0.2 0.23 11.3 0.2 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 RLN66725.1 - 0.11 12.9 0.2 0.19 12.1 0.2 1.3 1 0 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.10 RLN66725.1 - 0.12 11.9 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CLP1_P PF16575.5 RLN66725.1 - 0.14 11.9 0.1 0.51 10.1 0.1 1.8 1 1 1 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop VirC1 PF07015.11 RLN66725.1 - 0.16 11.3 0.1 0.35 10.1 0.0 1.5 2 0 0 2 2 2 0 VirC1 protein AAA_5 PF07728.14 RLN66725.1 - 0.21 11.6 0.1 0.36 10.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 RLN66725.1 - 0.23 10.6 0.3 0.33 10.1 0.3 1.2 1 0 0 1 1 1 0 NB-ARC domain Furin-like_2 PF15913.5 RLN66800.1 - 0.00018 21.6 6.7 0.00019 21.5 6.7 1.1 1 0 0 1 1 1 1 Furin-like repeat, cysteine-rich Dickkopf_N PF04706.12 RLN66800.1 - 0.091 13.3 9.4 0.33 11.5 9.4 2.0 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Stig1 PF04885.13 RLN66800.1 - 0.16 12.4 10.8 0.2 12.1 10.8 1.2 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 Tannase PF07519.11 RLN66801.1 - 4.5e-115 385.2 0.0 4.3e-70 236.9 0.0 2.1 2 0 0 2 2 2 2 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 RLN66801.1 - 0.023 14.2 0.1 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family ADP_PFK_GK PF04587.15 RLN66802.1 - 2e-96 323.2 0.0 2.8e-96 322.7 0.0 1.3 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region GST_N_3 PF13417.6 RLN66803.1 - 5.3e-14 52.4 0.3 1.2e-13 51.2 0.3 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 RLN66803.1 - 3.1e-10 40.1 3.2 3.1e-10 40.1 3.2 2.6 3 0 0 3 3 3 1 Glutaredoxin GST_N_2 PF13409.6 RLN66803.1 - 3.2e-07 30.6 0.1 6.2e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 RLN66803.1 - 6.9e-06 26.7 0.1 2.1e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_N PF02798.20 RLN66803.1 - 1.7e-05 25.1 0.0 4.3e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN66803.1 - 6e-05 23.0 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF836 PF05768.14 RLN66803.1 - 0.15 12.4 1.3 0.3 11.5 0.3 2.0 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) DUF4813 PF16072.5 RLN66803.1 - 0.64 9.6 9.0 0.86 9.2 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) FGAR-AT_N PF18076.1 RLN66804.1 - 1.8e-19 69.8 0.0 3.6e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal AIRS_C PF02769.22 RLN66804.1 - 7.9e-15 55.3 0.0 2e-14 54.0 0.0 1.7 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain FGAR-AT_linker PF18072.1 RLN66804.1 - 2e-10 41.0 0.0 5.6e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 RLN66804.1 - 0.0073 16.9 0.0 0.015 15.9 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain zf-C3HC4_3 PF13920.6 RLN66852.1 - 1.8e-11 43.7 6.5 3.9e-11 42.6 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN66852.1 - 2.7e-11 43.6 10.7 5.3e-11 42.7 10.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 RLN66852.1 - 1.3e-09 37.9 6.3 2.6e-09 36.9 6.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RLN66852.1 - 1.9e-09 37.2 9.8 3.8e-09 36.2 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN66852.1 - 4.5e-09 36.0 9.4 9e-09 35.1 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN66852.1 - 1.2e-08 34.7 6.8 2.7e-08 33.5 6.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN66852.1 - 4.6e-08 32.9 7.4 9.1e-08 31.9 7.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 RLN66852.1 - 1.9e-05 24.7 10.5 3.9e-05 23.7 10.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 RLN66852.1 - 4.7e-05 23.6 8.4 4.7e-05 23.6 8.4 2.0 2 1 0 2 2 2 1 RING-H2 zinc finger domain U-box PF04564.15 RLN66852.1 - 0.00022 21.4 0.0 0.00047 20.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_6 PF14835.6 RLN66852.1 - 0.00038 20.3 5.2 0.00074 19.3 5.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 RLN66852.1 - 0.0055 16.4 5.4 0.0055 16.4 5.4 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 RLN66852.1 - 0.024 14.7 2.1 0.024 14.7 2.1 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 RLN66852.1 - 0.082 12.7 4.2 0.13 12.0 4.2 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 RLN66852.1 - 0.084 12.5 7.1 0.043 13.4 4.5 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 RLN66852.1 - 0.56 10.4 5.5 1.3 9.2 5.5 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Peptidase_M20 PF01546.28 RLN66853.1 - 8.4e-46 156.3 0.0 5.5e-27 94.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 M20_dimer PF07687.14 RLN66853.1 - 1.2e-19 70.3 0.0 1.2e-08 34.8 0.0 2.6 2 1 0 2 2 2 2 Peptidase dimerisation domain Peptidase_M28 PF04389.17 RLN66853.1 - 6.6e-08 32.5 0.0 0.03 14.0 0.0 4.1 4 0 0 4 4 4 3 Peptidase family M28 Mito_carr PF00153.27 RLN66854.1 - 2.5e-34 117.1 1.4 1e-17 63.8 0.0 4.0 2 1 0 2 2 2 2 Mitochondrial carrier protein RCDG1 PF15725.5 RLN66856.1 - 5.4 7.5 7.8 4.1 7.9 0.3 3.1 3 1 0 3 3 3 0 Renal cancer differentiation gene 1 protein NMD3 PF04981.13 RLN66857.1 - 2.8e-76 256.2 6.4 2.8e-76 256.2 6.4 1.7 2 0 0 2 2 2 1 NMD3 family Aldedh PF00171.22 RLN66858.1 - 7.1e-37 127.0 0.0 1.4e-36 126.0 0.0 1.4 1 1 0 1 1 1 1 Aldehyde dehydrogenase family RNase_T PF00929.24 RLN66859.1 - 1.7e-07 32.0 0.1 5e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Exonuclease RCS1 PF07326.11 RLN66859.1 - 0.00097 19.1 0.4 0.0019 18.2 0.4 1.4 1 0 0 1 1 1 1 Regulator of chromosome segregation 1 Hus1 PF04005.12 RLN66860.1 - 2.3e-50 171.4 0.1 2.6e-50 171.2 0.1 1.0 1 0 0 1 1 1 1 Hus1-like protein Retrotran_gag_2 PF14223.6 RLN66861.1 - 4.8e-09 36.0 0.0 6.9e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 RLN66861.1 - 0.035 14.2 3.4 0.035 14.2 3.4 2.3 2 0 0 2 2 2 0 Zinc knuckle Cytochrome_C554 PF13435.6 RLN66861.1 - 0.063 14.2 1.5 0.18 12.8 1.5 1.8 1 0 0 1 1 1 0 Cytochrome c554 and c-prime vMSA PF00695.19 RLN66861.1 - 0.32 10.0 0.8 0.53 9.3 0.8 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus ORC6 PF05460.13 RLN66863.1 - 0.23 10.7 1.4 2.1 7.5 0.7 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) VPS13_C PF16909.5 RLN66864.1 - 9.7e-23 80.9 3.7 1.5e-20 73.7 0.4 2.6 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal C2 PF00168.30 RLN66864.1 - 1.5e-17 63.8 0.0 1.5e-11 44.5 0.0 2.8 2 0 0 2 2 2 2 C2 domain SHR-BD PF06650.12 RLN66864.1 - 3.5e-16 59.4 0.0 1.4e-15 57.4 0.0 2.1 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 EF-hand_1 PF00036.32 RLN66864.1 - 3e-12 45.2 0.9 3.3e-05 23.1 0.8 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RLN66864.1 - 2.4e-11 43.9 1.2 8.3e-11 42.2 1.2 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN66864.1 - 5e-11 41.6 1.8 0.00013 21.6 0.4 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RLN66864.1 - 3.7e-08 32.5 0.4 0.012 15.1 0.2 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RLN66864.1 - 1.3e-05 25.0 0.4 0.049 13.5 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain pair GHMP_kinases_C PF08544.13 RLN66865.1 - 2e-13 50.5 0.0 2.9e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 GHMP kinases C terminal Glyco_hydro81C PF17652.1 RLN66866.1 - 8.4e-89 298.2 1.4 1.3e-88 297.6 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 RLN66866.1 - 1.3e-31 110.0 0.1 3.8e-30 105.2 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain AA_permease_2 PF13520.6 RLN66866.1 - 7.3e-25 87.7 31.5 1.3e-24 86.8 31.5 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN66866.1 - 2.4e-12 46.2 21.5 8e-09 34.6 7.6 2.2 2 0 0 2 2 2 2 Amino acid permease Prefoldin PF02996.17 RLN66867.1 - 8.5e-14 51.5 0.5 1.3e-12 47.6 0.0 2.6 2 0 0 2 2 2 1 Prefoldin subunit p25-alpha PF05517.12 RLN66867.1 - 0.015 15.5 0.0 2.2 8.5 0.0 2.7 2 1 0 2 2 2 0 p25-alpha R2K_3 PF14243.6 RLN66867.1 - 0.017 15.2 1.9 0.045 13.7 1.9 1.7 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 DUF724 PF05266.14 RLN66867.1 - 0.047 13.5 2.4 0.11 12.4 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CH PF00307.31 RLN66867.1 - 0.063 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Calponin homology (CH) domain Peptidase_C5 PF00770.18 RLN66867.1 - 0.091 12.4 0.2 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 Adenovirus endoprotease PMC2NT PF08066.12 RLN66867.1 - 0.13 13.0 0.0 82 4.0 0.0 3.6 3 0 0 3 3 3 0 PMC2NT (NUC016) domain FAM76 PF16046.5 RLN66867.1 - 0.24 10.7 1.4 0.45 9.8 1.4 1.4 1 0 0 1 1 1 0 FAM76 protein FTA4 PF13093.6 RLN66867.1 - 3.6 7.4 9.2 0.89 9.4 0.7 2.6 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4200 PF13863.6 RLN66867.1 - 6.4 7.2 10.4 42 4.6 0.4 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) ACOX PF01756.19 RLN66868.1 - 4.6e-54 182.7 0.0 8.5e-54 181.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 RLN66868.1 - 2e-30 105.9 0.0 3.6e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 RLN66868.1 - 1e-12 48.1 0.0 3.2e-12 46.5 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 RLN66868.1 - 0.0062 17.2 0.0 0.019 15.6 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 RLN66868.1 - 0.01 16.0 0.1 0.034 14.3 0.0 2.0 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain CSD PF00313.22 RLN66869.1 - 7e-26 89.9 15.1 1.1e-06 28.4 0.3 9.2 9 0 0 9 9 9 4 'Cold-shock' DNA-binding domain R3H PF01424.22 RLN66869.1 - 2.7e-06 27.3 0.0 5.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 R3H domain S1-like PF14444.6 RLN66869.1 - 0.001 19.0 6.8 6.6 6.7 0.0 6.8 7 1 0 7 7 7 1 S1-like MazE_antitoxin PF04014.18 RLN66869.1 - 0.0092 15.9 1.3 25 5.0 0.0 4.3 4 0 0 4 4 4 1 Antidote-toxin recognition MazE, bacterial antitoxin S1_2 PF13509.6 RLN66869.1 - 0.049 13.7 0.6 0.49 10.5 0.2 2.6 2 0 0 2 2 2 0 S1 domain ThiS PF02597.20 RLN66869.1 - 0.11 13.2 1.5 13 6.5 0.0 4.7 5 0 0 5 5 5 0 ThiS family Hydrolase_4 PF12146.8 RLN66936.1 - 5e-09 35.8 0.2 2.7e-07 30.1 0.3 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 RLN66936.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) SLC12 PF03522.15 RLN66937.1 - 0.00047 19.3 0.1 0.00051 19.2 0.1 1.0 1 0 0 1 1 1 1 Solute carrier family 12 Glyco_transf_24 PF18404.1 RLN66938.1 - 1.7e-137 457.2 2.0 2.8e-137 456.5 2.0 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 RLN66938.1 - 1.1e-31 110.8 0.4 2.6e-26 93.1 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 RLN66938.1 - 2.9e-26 92.5 0.0 8.3e-26 91.0 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 RLN66938.1 - 8e-24 83.9 0.0 2.1e-23 82.5 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 RLN66938.1 - 3.9e-23 81.9 3.0 6.2e-23 81.2 0.9 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 RLN66938.1 - 1.5e-05 24.7 0.1 3.2e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Thioredoxin_15 PF18403.1 RLN66938.1 - 2.9e-05 24.1 1.7 0.2 11.5 0.0 3.8 3 0 0 3 3 3 2 Thioredoxin-like domain OAD_gamma PF04277.13 RLN66938.1 - 2.7 8.6 6.1 11 6.7 0.1 3.9 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain RRM_1 PF00076.22 RLN66939.1 - 2.7e-22 78.4 0.1 4.6e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 RLN66939.1 - 1.2e-15 57.9 3.4 1.2e-15 57.9 3.4 2.3 2 1 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal eIF-3_zeta PF05091.12 RLN66939.1 - 2.3 7.1 6.4 0.1 11.5 0.8 1.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Rhabdo_ncap PF00945.18 RLN66939.1 - 6.2 5.6 6.6 11 4.8 6.6 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Pkinase_Tyr PF07714.17 RLN66940.1 - 6.4e-25 87.9 0.0 9.1e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN66940.1 - 2.3e-17 63.2 0.0 3.5e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF1180 PF06679.12 RLN66940.1 - 0.046 14.1 3.2 0.24 11.8 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) CD34_antigen PF06365.12 RLN66940.1 - 0.049 13.2 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF202 PF02656.15 RLN66940.1 - 0.061 13.8 0.1 9.2 6.8 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF4366 PF14283.6 RLN66940.1 - 0.17 12.0 0.1 0.28 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) TrmO PF01980.16 RLN66941.1 - 1.2e-19 70.7 0.1 2.5e-10 40.6 0.0 2.5 1 1 1 2 2 2 2 tRNA-methyltransferase O TrmO_C PF18389.1 RLN66941.1 - 0.035 14.2 0.0 0.087 12.9 0.0 1.7 1 0 0 1 1 1 0 TrmO C-terminal domain YcgR PF07317.12 RLN66941.1 - 0.035 14.0 0.3 0.072 13.0 0.3 1.5 1 0 0 1 1 1 0 Flagellar regulator YcgR TPR_10 PF13374.6 RLN66941.1 - 0.22 11.4 3.6 0.17 11.8 1.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat VPS13 PF16908.5 RLN66942.1 - 5.4e-05 23.1 2.4 0.096 12.5 0.0 2.4 2 0 0 2 2 2 2 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 RLN66942.1 - 0.0041 17.2 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 AAA_12 PF13087.6 RLN66943.1 - 8.2e-50 169.2 0.0 1.4e-49 168.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RLN66943.1 - 1.8e-27 96.8 0.0 1.8e-27 96.8 0.0 2.5 2 1 0 2 2 1 1 AAA domain AAA_30 PF13604.6 RLN66943.1 - 8.4e-08 32.2 0.1 2e-07 30.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RLN66943.1 - 5.4e-05 23.6 0.1 0.00036 20.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RLN66943.1 - 6.2e-05 23.3 0.0 0.00044 20.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 RLN66943.1 - 0.00058 19.7 0.0 0.46 10.2 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 RLN66943.1 - 0.0013 17.9 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein YL1 PF05764.13 RLN66943.1 - 0.0038 17.4 18.6 0.0038 17.4 18.6 2.6 2 1 0 2 2 1 1 YL1 nuclear protein AAA PF00004.29 RLN66943.1 - 0.0059 17.0 0.0 0.015 15.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN66943.1 - 0.008 16.6 0.0 0.043 14.2 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 RLN66943.1 - 0.01 15.3 0.0 0.4 10.0 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 RLN66943.1 - 0.023 15.3 0.3 0.62 10.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain Rad17 PF03215.15 RLN66943.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 RLN66943.1 - 0.1 12.8 0.4 0.52 10.5 0.0 2.4 2 0 0 2 2 1 0 AAA domain DUF3787 PF12655.7 RLN66943.1 - 0.11 12.5 0.3 0.26 11.2 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3787) AAA_28 PF13521.6 RLN66943.1 - 0.11 12.7 0.1 0.54 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RLN66943.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 RLN66943.1 - 0.17 11.2 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Thiolase_N PF00108.23 RLN66944.1 - 7.2e-83 277.9 0.4 1.2e-81 273.9 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RLN66944.1 - 1.9e-48 163.2 0.8 5.5e-48 161.7 0.2 2.1 4 0 0 4 4 4 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 RLN66944.1 - 0.00016 21.3 6.7 0.1 12.2 0.2 4.1 3 1 1 4 4 4 3 Beta-ketoacyl synthase, N-terminal domain Clat_adaptor_s PF01217.20 RLN66945.1 - 2.2e-19 69.8 3.9 1.2e-13 51.2 0.7 2.4 1 1 1 2 2 2 2 Clathrin adaptor complex small chain Dimer_Tnp_hAT PF05699.14 RLN66945.1 - 2.9e-11 43.0 0.0 1.2e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 RLN66945.1 - 0.00023 21.1 1.5 0.00039 20.4 0.2 2.1 2 0 0 2 2 2 1 BED zinc finger DUF4413 PF14372.6 RLN66945.1 - 0.059 13.7 0.1 0.34 11.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) zf-C2H2_4 PF13894.6 RLN66945.1 - 0.12 13.3 2.7 0.22 12.4 1.5 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger FoP_duplication PF13865.6 RLN66945.1 - 0.29 11.7 2.0 0.8 10.3 2.0 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF4834 PF16118.5 RLN66947.1 - 0.059 14.3 0.1 0.12 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SusD_RagB PF07980.11 RLN66947.1 - 0.17 11.5 4.5 0.34 10.5 4.5 1.6 1 0 0 1 1 1 0 SusD family SecG PF03840.14 RLN66947.1 - 1.4 9.0 4.6 3.5 7.8 4.6 1.7 1 1 0 1 1 1 0 Preprotein translocase SecG subunit CH PF00307.31 RLN66948.1 - 9.4e-75 247.8 3.2 2.5e-19 69.5 0.2 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain Swi3 PF07962.12 RLN66948.1 - 3.7e-17 62.1 0.0 9.2e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 CAMSAP_CH PF11971.8 RLN66948.1 - 9.9e-09 34.9 0.6 0.078 12.8 0.0 4.6 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_7 PF13499.6 RLN66948.1 - 0.014 15.9 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair DUF5580 PF17743.1 RLN66948.1 - 0.021 13.4 0.0 0.035 12.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Metallophos PF00149.28 RLN66949.1 - 2e-10 41.5 0.2 9.6e-10 39.3 0.2 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Wzz PF02706.15 RLN66949.1 - 0.0046 17.2 0.0 0.0084 16.4 0.0 1.4 1 0 0 1 1 1 1 Chain length determinant protein DUF5107 PF17128.4 RLN66949.1 - 0.0083 15.3 3.0 0.015 14.5 3.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5107) Metallophos PF00149.28 RLN66950.1 - 5.7e-07 30.2 2.1 1.4e-06 29.0 0.7 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase ABC_tran PF00005.27 RLN66951.1 - 2.1e-57 193.4 0.0 1.8e-27 96.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 RLN66951.1 - 2.1e-40 138.9 34.2 2.1e-29 102.8 9.2 2.9 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 RLN66951.1 - 2.6e-23 83.3 0.4 1e-08 35.4 0.1 4.2 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RLN66951.1 - 0.00026 21.6 3.0 0.033 14.7 0.1 2.3 2 0 0 2 2 2 2 AAA domain MukB PF04310.12 RLN66951.1 - 0.0017 18.2 1.1 1.7 8.4 0.2 2.4 2 0 0 2 2 2 2 MukB N-terminal AAA_29 PF13555.6 RLN66951.1 - 0.0031 17.2 3.1 0.14 11.9 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN66951.1 - 0.0099 15.8 0.2 0.74 9.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 RLN66951.1 - 0.0099 15.3 0.0 8.6 5.7 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 RLN66951.1 - 0.025 14.3 0.0 0.58 9.8 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_30 PF13604.6 RLN66951.1 - 0.026 14.2 0.3 3.1 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 RLN66951.1 - 0.053 13.9 0.1 2.7 8.4 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 RLN66951.1 - 0.055 13.7 0.6 2.6 8.3 0.0 3.0 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 RLN66951.1 - 0.085 12.5 2.5 4.1 7.0 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CDK2AP PF09806.9 RLN66952.1 - 0.017 15.2 2.1 0.044 13.8 2.1 1.7 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Glyco_hydro_12 PF01670.16 RLN66953.1 - 0.0097 15.9 4.5 0.01 15.9 0.6 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 12 Elicitin PF00964.17 RLN66954.1 - 0.34 11.0 8.9 1.1 9.4 2.1 2.2 1 1 1 2 2 2 0 Elicitin Elicitin PF00964.17 RLN66955.1 - 0.01 15.9 21.1 0.73 10.0 7.5 3.6 2 2 1 3 3 3 0 Elicitin Beach PF02138.18 RLN66957.1 - 1.1e-114 382.5 0.0 2.3e-114 381.4 0.0 1.6 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 RLN66957.1 - 2.4e-15 56.5 0.0 5.3e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 RLN66957.1 - 2.7e-06 27.6 0.0 5.1e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily zf-C3HC4_3 PF13920.6 RLN66957.1 - 0.072 13.0 12.2 0.2 11.5 12.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN66957.1 - 0.17 11.8 10.2 0.46 10.4 10.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN66957.1 - 1.2 9.6 12.0 2.4 8.5 10.3 2.6 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 RLN66957.1 - 3.1 7.7 9.4 8.3 6.4 8.4 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN66957.1 - 3.9 7.5 11.1 9.6 6.3 11.1 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Guanylate_cyc PF00211.20 RLN66958.1 - 3.1e-94 313.7 0.1 3.4e-47 160.4 0.1 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 RLN66958.1 - 0.13 11.7 0.4 1.5 8.2 0.1 2.1 2 0 0 2 2 2 0 Heme NO binding associated TPR_1 PF00515.28 RLN66959.1 - 2.6e-11 42.8 9.1 0.0031 17.3 0.1 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN66959.1 - 2.8e-10 39.5 15.9 0.009 16.1 0.1 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN66959.1 - 1.4e-09 37.4 6.9 0.0042 17.2 0.0 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN66959.1 - 4.2e-09 36.6 8.7 0.04 14.2 0.0 5.1 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN66959.1 - 1.3e-08 34.3 10.8 1.1 9.5 0.0 6.7 6 2 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 RLN66959.1 - 1.2e-05 25.7 18.9 0.0019 18.7 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 RLN66959.1 - 0.0002 20.7 8.1 1 8.5 0.7 3.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 RLN66959.1 - 0.00031 21.3 11.5 1.1 10.3 0.3 5.2 3 3 3 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN66959.1 - 0.00044 20.3 3.5 0.61 10.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN66959.1 - 0.0005 20.3 0.5 5.1 7.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.17 RLN66959.1 - 0.00079 19.9 0.8 0.00079 19.9 0.8 2.5 2 1 0 2 2 2 1 Bacterial transcriptional activator domain ANAPC3 PF12895.7 RLN66959.1 - 0.002 18.3 6.0 0.038 14.2 0.2 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 RLN66959.1 - 0.0027 16.8 1.9 0.077 12.0 0.1 2.1 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 RLN66959.1 - 0.0034 17.9 4.3 0.65 10.8 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN66959.1 - 0.0044 17.6 8.3 6.5 7.5 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat Bcr-Abl_Oligo PF09036.10 RLN66959.1 - 0.013 15.5 0.6 1.6 8.8 0.4 2.7 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain BORCS8 PF10167.9 RLN66959.1 - 0.053 13.5 0.2 6.5 6.7 0.0 2.4 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 CENP-H PF05837.12 RLN66959.1 - 0.068 13.6 4.1 10 6.5 0.2 3.2 3 0 0 3 3 3 0 Centromere protein H (CENP-H) NARP1 PF12569.8 RLN66959.1 - 0.13 11.1 5.9 0.094 11.6 2.0 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 MIT PF04212.18 RLN66959.1 - 4.7 7.3 0.0 4.7 7.3 0.0 3.9 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain PALP PF00291.25 RLN66960.1 - 4.8e-33 114.8 0.1 5.7e-33 114.6 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PVL_ORF50 PF07768.11 RLN66961.1 - 0.073 13.4 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family MULE PF10551.9 RLN66963.1 - 1e-11 45.1 0.0 1.7e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 RLN66963.1 - 0.0029 17.3 0.2 0.0029 17.3 0.2 2.0 2 0 0 2 2 2 1 SWIM zinc finger IQ PF00612.27 RLN67011.1 - 0.0015 18.2 0.9 0.0015 18.2 0.9 3.4 3 0 0 3 3 3 2 IQ calmodulin-binding motif BT1 PF03092.16 RLN67012.1 - 8.4e-05 21.0 2.5 0.00075 17.9 0.2 2.9 2 1 0 3 3 3 2 BT1 family SKN1 PF03935.15 RLN67013.1 - 9.3e-63 212.3 14.1 2.2e-40 138.5 8.5 4.7 2 2 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Nodulin_late PF07127.11 RLN67013.1 - 1.7 9.1 5.2 2.6 8.4 0.4 2.8 3 0 0 3 3 3 0 Late nodulin protein SKN1 PF03935.15 RLN67014.1 - 1.2e-59 202.1 21.8 8.6e-38 130.0 9.1 4.7 2 2 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Sugarporin_N PF11471.8 RLN67014.1 - 0.62 10.1 2.3 1.4 9.0 2.3 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Nodulin_late PF07127.11 RLN67014.1 - 2.6 8.5 4.3 3.4 8.1 0.3 3.0 3 0 0 3 3 3 0 Late nodulin protein SKN1 PF03935.15 RLN67015.1 - 6.9e-60 202.9 18.4 2e-38 132.1 9.6 4.9 2 2 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) EB PF01683.18 RLN67015.1 - 1 9.7 6.3 0.33 11.3 1.9 2.6 2 1 0 2 2 2 0 EB module Nodulin_late PF07127.11 RLN67015.1 - 3.2 8.2 5.4 2.1 8.8 0.4 2.9 3 0 0 3 3 3 0 Late nodulin protein SKN1 PF03935.15 RLN67016.1 - 2e-61 207.9 17.8 2.5e-39 135.1 9.1 4.7 2 2 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) EB PF01683.18 RLN67016.1 - 8.3 6.8 10.1 0.38 11.1 2.3 2.9 3 0 0 3 3 3 0 EB module ELMO_CED12 PF04727.13 RLN67017.1 - 3.1e-33 115.3 0.0 6.9e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family UBM PF14377.6 RLN67017.1 - 2.1e-06 27.0 0.1 9.1e-06 25.0 0.1 2.1 1 0 0 1 1 1 1 Ubiquitin binding region zf-RanBP PF00641.18 RLN67017.1 - 0.00018 20.7 1.0 0.00036 19.8 1.0 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF961 PF06125.11 RLN67017.1 - 0.074 13.4 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF961) PEP-utilizers PF00391.23 RLN67017.1 - 0.15 11.8 0.0 0.43 10.3 0.0 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain Wza_C PF18412.1 RLN67017.1 - 0.21 11.4 1.1 0.41 10.5 0.0 2.1 2 0 0 2 2 2 0 Outer-membrane lipoprotein Wza C-terminal domain GED PF02212.18 RLN67017.1 - 4.1 7.6 5.6 8.5 6.6 2.3 2.6 1 1 1 2 2 2 0 Dynamin GTPase effector domain Acyltransferase PF01553.21 RLN67018.1 - 4.5e-18 65.2 0.0 1.1e-17 63.9 0.0 1.6 2 0 0 2 2 2 1 Acyltransferase Acyltransf_C PF16076.5 RLN67018.1 - 2.7e-14 53.0 0.3 4.6e-14 52.3 0.3 1.3 1 0 0 1 1 1 1 Acyltransferase C-terminus RUN PF02759.19 RLN67018.1 - 0.071 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 RUN domain SKN1 PF03935.15 RLN67020.1 - 1.4e-57 195.2 25.8 8.6e-38 130.0 10.0 4.8 1 1 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) BT1 PF03092.16 RLN67021.1 - 2.3e-06 26.1 16.6 2.7e-06 25.9 2.6 3.1 3 1 0 3 3 3 2 BT1 family DUF1980 PF09323.10 RLN67021.1 - 5 7.0 5.6 2.8 7.8 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) DDHD PF02862.17 RLN67022.1 - 0.015 15.5 0.4 0.018 15.2 0.4 1.0 1 0 0 1 1 1 0 DDHD domain Pribosyltran PF00156.27 RLN67023.1 - 2.7e-07 30.2 0.0 3.4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain LRR_6 PF13516.6 RLN67024.1 - 0.0016 18.3 8.7 0.17 12.0 0.1 5.5 7 0 0 7 7 7 1 Leucine Rich repeat LRR_4 PF12799.7 RLN67024.1 - 0.0034 17.8 7.3 0.075 13.5 0.9 4.5 2 1 3 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN67024.1 - 0.023 15.2 2.7 11 7.0 0.3 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat CHAD PF05235.14 RLN67024.1 - 0.042 13.8 0.4 0.073 13.0 0.4 1.3 1 0 0 1 1 1 0 CHAD domain CTP_transf_1 PF01148.20 RLN67025.1 - 4.6e-40 138.1 12.1 7.5e-40 137.4 12.1 1.4 1 1 0 1 1 1 1 Cytidylyltransferase family CarS-like PF01864.17 RLN67025.1 - 0.016 15.2 0.5 0.016 15.2 0.5 2.6 2 1 0 2 2 2 0 CDP-archaeol synthase DUF2254 PF10011.9 RLN67025.1 - 1.6 7.5 7.3 0.049 12.4 1.2 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) Cu_bind_like PF02298.17 RLN67029.1 - 0.051 13.6 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Plastocyanin-like domain TLE_N PF03920.15 RLN67030.1 - 0.0033 17.5 0.3 0.0062 16.6 0.3 1.5 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain HAUS6_N PF14661.6 RLN67031.1 - 0.066 12.8 5.0 0.11 12.0 5.0 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus NYD-SP28_assoc PF14775.6 RLN67032.1 - 0.0094 16.0 1.7 0.0094 16.0 1.7 2.4 2 0 0 2 2 2 1 Sperm tail C-terminal domain Atg14 PF10186.9 RLN67032.1 - 0.14 11.3 6.8 0.19 10.8 6.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KASH_CCD PF14662.6 RLN67032.1 - 0.8 9.5 10.2 4.4 7.1 3.1 2.4 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH bZIP_2 PF07716.15 RLN67032.1 - 8.9 6.5 16.7 2 8.5 8.9 2.7 2 0 0 2 2 2 0 Basic region leucine zipper Seryl_tRNA_N PF02403.22 RLN67033.1 - 0.032 14.4 2.0 0.16 12.2 0.1 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TFIIA PF03153.13 RLN67089.1 - 2e-05 24.8 21.3 2.6e-05 24.4 21.3 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 RLN67089.1 - 0.46 10.1 8.9 0.83 9.2 8.9 1.5 1 0 0 1 1 1 0 Spt20 family zf-CCCH PF00642.24 RLN67090.1 - 1.4e-09 37.6 2.7 3.6e-09 36.3 2.7 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RLN67090.1 - 1.9e-05 24.6 4.5 4.5e-05 23.4 4.5 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-RING_2 PF13639.6 RLN67090.1 - 0.00011 22.4 8.8 0.00041 20.6 8.8 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RLN67090.1 - 0.00015 21.5 9.1 0.0021 17.9 9.2 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 RLN67090.1 - 0.00049 19.8 2.8 0.00049 19.8 2.8 2.1 2 0 0 2 2 2 1 CCCH-type zinc finger zf-RING_5 PF14634.6 RLN67090.1 - 0.0011 18.9 11.6 0.0035 17.3 11.6 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RLN67090.1 - 0.0023 17.7 8.0 0.0058 16.5 8.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN67090.1 - 0.012 15.7 7.5 0.034 14.2 7.5 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_10 PF16685.5 RLN67090.1 - 0.026 14.6 4.1 0.026 14.6 4.1 2.0 2 0 0 2 2 1 0 zinc RING finger of MSL2 zf-C3HC4_2 PF13923.6 RLN67090.1 - 0.13 12.1 10.5 1.4 8.8 10.5 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RLN67090.1 - 1.5 9.0 9.3 9.7 6.5 5.0 2.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RLN67090.1 - 1.7 8.6 8.6 0.75 9.7 4.9 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FYVE PF01363.21 RLN67090.1 - 2.9 8.1 10.8 9.4 6.5 10.8 1.8 1 1 0 1 1 1 0 FYVE zinc finger DinB_2 PF12867.7 RLN67093.1 - 1.7e-06 28.6 0.8 2.4e-06 28.1 0.8 1.4 1 0 0 1 1 1 1 DinB superfamily Glutaredoxin PF00462.24 RLN67094.1 - 7.9e-22 77.2 0.0 1.1e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 RLN67094.1 - 0.00029 21.2 0.0 0.00043 20.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 RLN67094.1 - 0.00054 20.3 0.0 0.00072 19.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 RLN67094.1 - 0.0011 18.7 0.5 0.69 9.7 0.1 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 RLN67094.1 - 0.007 16.5 0.5 1.6 8.8 0.2 2.1 1 1 1 2 2 2 2 Thioredoxin GST_N_2 PF13409.6 RLN67094.1 - 0.013 15.8 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.6 RLN67094.1 - 0.054 13.5 0.1 0.095 12.8 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin domain GST_N PF02798.20 RLN67094.1 - 0.065 13.6 0.0 0.092 13.1 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 RLN67094.1 - 0.086 13.3 0.1 0.11 13.0 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain APG6_N PF17675.1 RLN67095.1 - 0.013 16.1 6.1 0.02 15.4 2.3 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region ACCA PF03255.14 RLN67095.1 - 0.14 12.0 0.2 13 5.6 0.0 2.6 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF3450 PF11932.8 RLN67095.1 - 0.18 11.1 5.2 0.059 12.7 2.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4200 PF13863.6 RLN67095.1 - 0.21 12.0 5.8 0.065 13.6 1.8 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) DUF2205 PF10224.9 RLN67095.1 - 0.33 11.0 2.0 1.9 8.6 0.8 2.5 2 0 0 2 2 2 0 Short coiled-coil protein GIT_CC PF16559.5 RLN67095.1 - 0.71 9.8 3.6 1.3 8.9 2.0 2.3 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor AAA_32 PF13654.6 RLN67109.1 - 0.009 14.8 0.2 0.02 13.7 0.5 1.4 2 0 0 2 2 2 1 AAA domain Not3 PF04065.15 RLN67109.1 - 0.064 12.7 0.3 0.11 11.9 0.3 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Gpi1 PF05024.15 RLN67110.1 - 1.7e-45 155.4 2.4 3e-45 154.6 2.4 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Tctex-1 PF03645.13 RLN67111.1 - 0.18 12.1 2.7 1 9.7 0.0 2.9 3 0 0 3 3 3 0 Tctex-1 family Cation_efflux PF01545.21 RLN67112.1 - 1.3 8.7 5.8 0.76 9.5 0.2 2.8 3 0 0 3 3 3 0 Cation efflux family Swi5 PF07061.11 RLN67113.1 - 0.019 15.0 3.6 4.2 7.5 0.0 3.5 2 1 0 2 2 2 0 Swi5 Allexi_40kDa PF05549.11 RLN67113.1 - 0.034 13.7 2.4 0.065 12.7 2.4 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF1284 PF06935.11 RLN67113.1 - 0.76 10.2 3.7 2 8.9 3.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1284) LMBR1 PF04791.16 RLN67113.1 - 2.6 6.8 7.1 5.4 5.8 7.1 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DLP_helical PF18709.1 RLN67113.1 - 3.7 6.7 11.2 6.6 5.8 11.2 1.3 1 0 0 1 1 1 0 Dynamin-like helical domain FUSC PF04632.12 RLN67113.1 - 8.1 4.8 20.5 16 3.9 20.5 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family HLH PF00010.26 RLN67114.1 - 4.7e-09 36.1 1.9 8.8e-09 35.2 1.9 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 RLN67114.1 - 0.0032 17.4 0.0 0.0075 16.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_5 PF07310.13 RLN67114.1 - 0.0083 15.9 0.1 0.055 13.3 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 RLN67114.1 - 0.024 14.9 0.0 0.051 13.8 0.0 1.6 1 0 0 1 1 1 0 PAS fold MRPL52 PF18699.1 RLN67114.1 - 0.048 13.9 0.2 0.048 13.9 0.2 2.4 1 1 1 2 2 2 0 Mitoribosomal protein mL52 PAS_9 PF13426.7 RLN67114.1 - 0.14 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 PAS domain HLH PF00010.26 RLN67115.1 - 2.1e-08 34.0 1.5 3.6e-08 33.3 1.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain UDG PF03167.19 RLN67117.1 - 9.9e-15 54.8 0.0 1.6e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Importin_rep_6 PF18829.1 RLN67118.1 - 0.78 9.9 3.0 2.1 8.5 0.5 2.8 2 0 0 2 2 2 0 Importin repeat 6 DUF2207 PF09972.9 RLN67119.1 - 0.066 12.0 0.0 0.077 11.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Romo1 PF10247.9 RLN67119.1 - 0.092 13.1 3.9 3.7 8.0 3.7 2.5 1 1 1 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 ABC_export PF16962.5 RLN67119.1 - 0.29 9.5 4.0 0.37 9.2 4.0 1.1 1 0 0 1 1 1 0 Putative ABC exporter RRN3 PF05327.11 RLN67123.1 - 0.025 13.1 0.1 0.027 13.0 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 RLN67123.1 - 0.061 11.5 1.3 0.072 11.3 1.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RLN67123.1 - 0.089 12.2 1.9 0.12 11.8 1.9 1.2 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.6 RLN67123.1 - 0.3 10.7 1.7 0.58 9.8 1.7 1.4 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 RLN67123.1 - 0.4 10.7 3.2 0.78 9.8 3.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 RLN67123.1 - 0.86 8.7 11.4 1.3 8.1 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 RLN67123.1 - 0.87 7.8 3.4 1.3 7.3 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 RLN67123.1 - 1 9.2 4.2 1.6 8.6 4.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Sporozoite_P67 PF05642.11 RLN67123.1 - 1.6 6.7 4.2 2.5 6.1 4.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 RLN67123.1 - 3.7 5.5 11.8 5.1 5.1 11.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sugar_tr PF00083.24 RLN67124.1 - 3.1e-50 171.3 21.0 4e-50 171.0 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN67124.1 - 5.9e-45 153.7 54.1 3.1e-40 138.2 34.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 RLN67124.1 - 0.0036 16.6 2.2 0.0036 16.6 2.2 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB BT1 PF03092.16 RLN67124.1 - 0.3 9.3 7.2 0.06 11.6 0.3 2.6 4 0 0 4 4 4 0 BT1 family DUF599 PF04654.12 RLN67124.1 - 0.49 9.8 6.4 1 8.8 1.7 2.7 2 0 0 2 2 2 0 Protein of unknown function, DUF599 PAN_4 PF14295.6 RLN67186.1 - 5.5e-40 135.1 36.5 5.3e-11 42.2 3.7 4.4 4 0 0 4 4 4 4 PAN domain PAN_2 PF08276.11 RLN67186.1 - 0.0043 17.2 41.0 0.34 11.1 5.2 4.3 4 0 0 4 4 4 4 PAN-like domain DUF1424 PF07232.11 RLN67186.1 - 0.011 14.7 1.5 2.6 6.9 0.0 2.6 2 1 1 3 3 3 0 Putative rep protein (DUF1424) LRR_8 PF13855.6 RLN67187.1 - 0.09 12.6 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 Leucine rich repeat LRR_8 PF13855.6 RLN67188.1 - 0.046 13.5 0.4 3.5 7.5 0.0 3.1 3 0 0 3 3 3 0 Leucine rich repeat SDF PF00375.18 RLN67189.1 - 2.8e-26 92.4 38.5 1.2e-25 90.3 38.5 1.9 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family CPBP PF02517.16 RLN67190.1 - 3.3e-13 49.8 5.1 3.3e-13 49.8 5.1 2.6 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease DUF2496 PF10689.9 RLN67190.1 - 0.059 13.2 0.4 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2496) Lectin_N PF03954.14 RLN67190.1 - 0.081 12.7 1.4 3.9 7.2 0.2 2.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain SDF PF00375.18 RLN67191.1 - 5.3e-45 154.1 30.9 1.6e-44 152.5 30.9 1.6 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family PseudoU_synth_1 PF01416.20 RLN67192.1 - 6.6e-30 103.8 0.0 4e-17 62.6 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase SAM_1 PF00536.30 RLN67193.1 - 5.6e-15 55.5 0.1 1.1e-14 54.5 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RLN67193.1 - 1.2e-14 54.1 0.0 3.2e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IQ PF00612.27 RLN67193.1 - 4.1e-10 38.5 36.1 0.0057 16.4 1.9 7.3 7 0 0 7 7 7 5 IQ calmodulin-binding motif Response_reg PF00072.24 RLN67193.1 - 4.1e-09 36.6 0.0 9.7e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Ank PF00023.30 RLN67193.1 - 2.2e-05 24.7 0.7 8.3e-05 22.9 0.7 2.1 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 RLN67193.1 - 2.5e-05 24.3 0.2 0.0017 18.7 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 RLN67193.1 - 6.4e-05 23.5 0.1 0.00087 19.8 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN67193.1 - 0.00015 22.0 0.7 0.012 15.9 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN67193.1 - 0.0023 18.5 0.0 0.012 16.1 0.0 2.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) RVT_3 PF13456.6 RLN67194.1 - 4.2e-24 84.7 0.2 5.7e-24 84.3 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 RLN67194.1 - 7.2e-13 48.9 0.1 1.4e-12 48.0 0.1 1.5 1 1 0 1 1 1 1 RNase H Med30 PF11315.8 RLN67194.1 - 0.095 12.9 0.2 0.12 12.6 0.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 30 ANAPC4_WD40 PF12894.7 RLN67195.1 - 4.2e-11 43.0 0.0 0.003 17.8 0.0 6.2 7 0 0 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Synaptobrevin PF00957.21 RLN67195.1 - 0.0056 16.5 1.2 0.012 15.4 1.2 1.5 1 0 0 1 1 1 1 Synaptobrevin PDZ PF00595.24 RLN67195.1 - 0.014 15.7 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 PDZ domain WD40 PF00400.32 RLN67195.1 - 0.024 15.5 0.8 35 5.5 0.0 5.2 5 0 0 5 5 5 0 WD domain, G-beta repeat SLATT_1 PF18181.1 RLN67195.1 - 0.046 13.7 0.4 0.11 12.4 0.4 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 PDZ_6 PF17820.1 RLN67195.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 PDZ domain UFD1 PF03152.14 RLN67196.1 - 6.6e-10 38.7 0.0 3.3e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin fusion degradation protein UFD1 Mitofilin PF09731.9 RLN67202.1 - 3.8 6.2 8.1 4.2 6.1 8.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Metallophos PF00149.28 RLN67262.1 - 6.7e-09 36.5 0.0 7.9e-07 29.8 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase GBP PF02263.19 RLN67263.1 - 2.5e-24 85.9 0.0 3e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain LeuA_dimer PF08502.10 RLN67265.1 - 1.7e-35 121.8 2.3 3.7e-35 120.7 2.3 1.6 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain SAM_1 PF00536.30 RLN67266.1 - 4.2e-14 52.7 0.0 1.2e-13 51.3 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RLN67266.1 - 1.4e-12 47.6 0.0 3.7e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_5 PF13857.6 RLN67266.1 - 1.3e-10 41.3 0.7 7.4e-07 29.3 0.3 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN67266.1 - 3.3e-08 33.9 0.1 7.9e-05 23.1 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN67266.1 - 3.5e-08 33.9 0.1 1.6e-07 31.8 0.1 2.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 RLN67266.1 - 0.00011 22.4 0.8 0.64 10.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 RLN67266.1 - 0.00022 21.4 0.2 0.44 11.3 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat IQ PF00612.27 RLN67266.1 - 0.00033 20.2 30.2 0.45 10.4 0.2 7.0 6 0 0 6 6 6 4 IQ calmodulin-binding motif BLOC1_2 PF10046.9 RLN67266.1 - 0.94 9.8 7.3 0.2 12.0 1.8 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3126 PF11324.8 RLN67266.1 - 1 9.3 4.0 18 5.2 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3126) Oxidored_q2 PF00420.24 RLN67267.1 - 0.073 12.7 0.1 8.8 6.0 0.0 2.7 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L PhoLip_ATPase_C PF16212.5 RLN67268.1 - 1.6e-64 218.1 30.2 1.6e-64 218.1 30.2 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RLN67268.1 - 1.2e-14 53.8 2.1 3.8e-14 52.1 2.1 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 RLN67268.1 - 2.6e-12 46.6 0.0 2.1e-11 43.8 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RLN67268.1 - 3.2e-10 40.6 0.2 0.0024 18.2 0.0 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RLN67268.1 - 1.3e-05 24.8 0.1 6.3e-05 22.6 0.1 2.3 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RLN67268.1 - 0.0027 17.5 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 RLN67269.1 - 2.2e-25 89.5 0.0 5.6e-22 78.4 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN67269.1 - 7.7e-25 87.6 0.1 3.2e-20 72.5 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Ank_2 PF12796.7 RLN67269.1 - 1.5e-11 44.7 0.0 9.5e-11 42.1 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN67269.1 - 1.5e-11 44.5 0.0 4e-07 30.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN67269.1 - 1.8e-08 34.0 0.0 0.00046 20.4 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 RLN67269.1 - 5.6e-07 29.7 0.0 0.0004 20.6 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN67269.1 - 2.8e-06 27.5 0.1 0.0026 18.1 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Kdo PF06293.14 RLN67269.1 - 0.056 12.8 0.0 0.54 9.6 0.0 2.4 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 RLN67270.1 - 2.5e-28 99.1 0.0 5.5e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN67270.1 - 1.1e-24 87.3 0.0 2.3e-24 86.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 RLN67270.1 - 0.0018 17.7 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Bac_DNA_binding PF00216.21 RLN67270.1 - 0.011 15.9 0.0 0.034 14.4 0.0 1.8 1 0 0 1 1 1 0 Bacterial DNA-binding protein EF-G-binding_N PF07299.11 RLN67270.1 - 0.13 12.8 1.0 2.2 8.8 0.1 2.4 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal DUF2972 PF11186.8 RLN67270.1 - 0.61 10.0 4.5 2.5 8.0 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2972) ALO PF04030.14 RLN67274.1 - 5.1e-21 75.7 1.6 5.9e-20 72.2 1.6 2.1 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 RLN67274.1 - 2e-17 63.2 0.0 3.6e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain RCC1 PF00415.18 RLN67355.1 - 4.5e-15 56.0 15.0 2.5e-07 31.2 0.1 5.0 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN67355.1 - 5e-14 51.7 17.7 1.9e-05 24.3 2.3 5.4 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat SAP PF02037.27 RLN67355.1 - 0.0027 17.4 2.4 0.0051 16.5 2.4 1.5 1 0 0 1 1 1 1 SAP domain GAD-like PF08887.11 RLN67355.1 - 0.1 12.4 0.0 14 5.5 0.0 3.0 3 0 0 3 3 3 0 GAD-like domain Metallophos PF00149.28 RLN67356.1 - 7.5e-07 29.9 0.0 1.2e-05 25.9 0.0 2.2 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 RLN67356.1 - 0.00076 19.9 0.0 0.0024 18.3 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN67356.1 - 0.0016 17.9 0.0 3 7.6 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN67356.1 - 0.0026 17.6 0.1 5.2 7.3 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 RLN67356.1 - 0.064 13.1 0.8 3.3 7.6 0.0 2.6 1 1 1 2 2 2 0 EF-hand domain pair HTH_32 PF13565.6 RLN67356.1 - 0.087 13.4 2.0 11 6.7 0.4 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DUF444 PF04285.12 RLN67356.1 - 0.1 11.7 0.6 0.14 11.2 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF444) DUF3135 PF11333.8 RLN67362.1 - 0.11 12.8 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) Metallophos PF00149.28 RLN67364.1 - 6e-12 46.5 0.0 8e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_3 PF00933.21 RLN67369.1 - 7.7e-52 176.6 0.0 9.9e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN67369.1 - 4.8e-36 124.6 0.0 8.8e-36 123.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RLN67369.1 - 3.3e-11 43.1 0.1 8.3e-11 41.8 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain SNARE_assoc PF09335.11 RLN67412.1 - 9.7e-17 61.6 9.8 9.7e-17 61.6 9.8 3.2 2 1 1 3 3 3 1 SNARE associated Golgi protein HTH_OrfB_IS605 PF12323.8 RLN67412.1 - 1.6e-10 40.3 4.1 1.7e-10 40.2 2.7 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain OrfB_IS605 PF01385.19 RLN67412.1 - 0.00035 20.8 0.0 0.0009 19.5 0.0 1.6 1 0 0 1 1 1 1 Probable transposase ABC2_membrane PF01061.24 RLN67413.1 - 2.6e-64 216.5 61.5 5.7e-35 120.7 20.7 3.3 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN67413.1 - 3e-29 102.3 0.0 3e-13 50.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN67413.1 - 1.2e-09 38.4 1.9 0.0024 17.7 0.0 3.5 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system Frag1 PF10277.9 RLN67413.1 - 7.7e-08 32.1 4.6 7.7e-08 32.1 4.6 2.4 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family RsgA_GTPase PF03193.16 RLN67413.1 - 3.9e-06 26.9 2.1 0.025 14.5 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 RLN67413.1 - 1.2e-05 25.0 6.9 0.027 14.2 0.6 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN67413.1 - 1.4e-05 25.6 1.3 0.041 14.3 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 RLN67413.1 - 6.6e-05 22.4 0.5 0.98 8.8 0.0 3.9 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 RLN67413.1 - 8e-05 22.3 1.6 0.032 13.8 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RLN67413.1 - 0.00048 20.4 0.4 1.5 9.1 0.1 2.6 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 RLN67413.1 - 0.0011 18.2 8.2 0.0011 18.2 8.2 4.0 4 1 0 4 4 4 2 ABC-2 family transporter protein AAA_23 PF13476.6 RLN67413.1 - 0.0019 18.7 0.6 0.21 12.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RLN67413.1 - 0.077 12.7 0.9 6 6.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 RLN67413.1 - 0.08 13.0 2.5 3.7 7.7 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 RLN67413.1 - 0.098 13.2 1.3 14 6.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 RLN67413.1 - 0.18 11.1 0.6 7.2 5.8 0.4 2.3 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 RLN67413.1 - 0.34 10.8 2.6 15 5.5 0.1 2.7 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 RLN67413.1 - 0.61 9.8 2.0 6.6 6.5 0.4 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 RLN67413.1 - 1.3 8.6 4.2 1 8.9 0.6 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 RLN67413.1 - 2.5 8.1 5.5 4 7.5 0.6 2.7 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 RLN67413.1 - 3 7.9 6.6 16 5.5 1.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Elicitin PF00964.17 RLN67414.1 - 3.3e-15 56.0 1.3 5.7e-15 55.2 1.3 1.4 1 0 0 1 1 1 1 Elicitin NADHdh PF00146.21 RLN67414.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 NADH dehydrogenase PUB PF09409.10 RLN67415.1 - 1.4e-19 69.8 0.0 2.9e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 PUB domain Piwi PF02171.17 RLN67416.1 - 4.1e-11 42.7 0.1 5.7e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 Piwi domain Nnf1 PF03980.14 RLN67416.1 - 0.0059 17.0 0.1 0.013 15.9 0.1 1.6 1 0 0 1 1 1 1 Nnf1 PUB PF09409.10 RLN67419.1 - 4e-15 55.5 0.0 1e-14 54.2 0.0 1.8 1 0 0 1 1 1 1 PUB domain DUF5572 PF17733.1 RLN67419.1 - 7.1e-13 48.2 1.2 2.9e-10 39.8 0.0 2.6 2 0 0 2 2 2 2 Family of unknown function (DUF5572) Tir_receptor_C PF07489.11 RLN67419.1 - 0.033 14.2 10.4 0.05 13.6 10.4 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus ADH_N PF08240.12 RLN67420.1 - 9.3e-26 89.9 1.6 9.3e-26 89.9 1.6 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN67420.1 - 2.1e-25 89.2 0.4 3.6e-25 88.4 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN67420.1 - 5e-07 30.8 0.1 8.6e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 RLN67420.1 - 0.052 13.0 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 RLN67420.1 - 0.063 12.6 0.3 0.14 11.4 0.3 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.21 RLN67420.1 - 0.15 11.5 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.24 RLN67421.1 - 2.1e-121 406.0 21.6 4.9e-121 404.7 21.6 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN67421.1 - 2.3e-26 92.6 56.6 6.6e-24 84.5 30.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 60KD_IMP PF02096.20 RLN67421.1 - 2 8.3 11.2 9.1 6.2 3.2 3.1 2 1 1 3 3 3 0 60Kd inner membrane protein ADH_N PF08240.12 RLN67422.1 - 1.7e-25 89.0 3.6 1.7e-25 89.0 3.6 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN67422.1 - 6.5e-23 81.1 0.1 1.1e-22 80.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN67422.1 - 0.011 16.7 0.0 0.023 15.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase adh_short PF00106.25 RLN67422.1 - 0.043 13.3 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 RLN67422.1 - 0.13 11.6 0.2 0.23 10.7 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_hydro_72 PF03198.14 RLN67434.1 - 4.4e-15 55.7 0.0 5e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase DAGAT PF03982.13 RLN67435.1 - 4.5e-26 91.5 0.0 3.7e-25 88.4 0.0 1.9 1 1 0 1 1 1 1 Diacylglycerol acyltransferase Glyco_hydro_72 PF03198.14 RLN67436.1 - 1.8e-14 53.7 0.0 2.2e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase CAP PF00188.26 RLN67513.1 - 3.4e-18 66.7 2.6 8.2e-18 65.4 2.6 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 RLN67514.1 - 2.7e-46 157.5 19.3 3.6e-23 82.8 5.5 2.3 2 0 0 2 2 2 2 Cysteine-rich secretory protein family SbsC_C PF18058.1 RLN67514.1 - 0.0012 19.1 2.9 0.29 11.4 0.5 2.2 2 0 0 2 2 2 2 SbsC C-terminal domain DUF276 PF03434.13 RLN67514.1 - 0.2 10.8 0.5 3.7 6.6 0.0 2.1 2 0 0 2 2 2 0 DUF276 CAP PF00188.26 RLN67515.1 - 5e-21 75.8 5.3 1e-20 74.9 5.3 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ATF7IP_BD PF16788.5 RLN67515.1 - 2.2 8.4 7.4 0.85 9.7 4.1 1.8 2 0 0 2 2 2 0 ATF-interacting protein binding domain Hydrolase_4 PF12146.8 RLN67517.1 - 0.00037 19.8 0.0 0.44 9.8 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN67517.1 - 0.025 14.2 0.0 0.85 9.2 0.0 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF915 PF06028.11 RLN67517.1 - 0.035 13.4 0.1 0.051 12.9 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 RLN67518.1 - 5.8e-07 29.4 0.0 9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN67518.1 - 1.4e-05 24.5 0.0 2.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF915 PF06028.11 RLN67518.1 - 0.00036 19.9 0.0 0.00057 19.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.7 RLN67518.1 - 0.0025 18.5 0.2 0.052 14.1 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Phage_holin_2_4 PF16082.5 RLN67518.1 - 0.07 12.9 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Pkinase PF00069.25 RLN67565.1 - 1e-46 159.5 0.0 1.5e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN67565.1 - 3.1e-46 157.8 0.0 4e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 RLN67565.1 - 1.5e-06 27.8 1.0 0.0014 18.3 0.1 2.2 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 RLN67565.1 - 5.4e-05 23.5 0.6 0.0061 16.9 0.0 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) DUF1180 PF06679.12 RLN67565.1 - 0.00092 19.7 1.5 0.0019 18.6 1.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Pkinase_fungal PF17667.1 RLN67565.1 - 0.0023 16.8 0.0 0.04 12.7 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 RLN67565.1 - 0.022 14.7 0.1 0.038 13.9 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family TNFR_16_TM PF18422.1 RLN67565.1 - 0.023 14.6 0.9 0.041 13.8 0.9 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain TMEM154 PF15102.6 RLN67565.1 - 0.031 14.2 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family MAP17 PF15807.5 RLN67565.1 - 0.033 14.4 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 PMP1_2 PF08114.11 RLN67565.1 - 0.054 13.2 0.5 0.16 11.7 0.5 1.8 1 0 0 1 1 1 0 ATPase proteolipid family Velvet PF11754.8 RLN67565.1 - 0.06 13.3 0.3 0.11 12.4 0.3 1.4 1 0 0 1 1 1 0 Velvet factor FeoB_associated PF12669.7 RLN67565.1 - 0.17 12.3 0.2 0.37 11.2 0.2 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF202 PF02656.15 RLN67565.1 - 0.17 12.3 1.5 0.3 11.6 0.3 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF202) FNIP PF05725.12 RLN67565.1 - 0.19 11.9 0.0 0.45 10.7 0.0 1.7 1 0 0 1 1 1 0 FNIP Repeat LRR_9 PF14580.6 RLN67566.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Leucine-rich repeat Pkinase PF00069.25 RLN67567.1 - 1.8e-17 63.6 0.0 2.2e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN67567.1 - 6.9e-16 58.3 0.0 9.4e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN67568.1 - 7e-99 330.5 0.0 9.9e-50 169.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN67568.1 - 1.7e-93 312.7 0.0 4.4e-46 157.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase LRR_8 PF13855.6 RLN67568.1 - 1.7e-07 30.9 5.3 0.0013 18.4 0.7 3.7 4 1 0 4 4 4 2 Leucine rich repeat Pkinase_fungal PF17667.1 RLN67568.1 - 1.9e-07 30.2 0.0 0.0095 14.8 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase LRR_4 PF12799.7 RLN67568.1 - 6.4e-07 29.6 8.4 0.02 15.3 1.2 5.8 4 1 4 8 8 8 1 Leucine Rich repeats (2 copies) APH PF01636.23 RLN67568.1 - 8.2e-05 22.6 0.5 0.21 11.4 0.2 3.2 2 1 0 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN67568.1 - 0.0013 17.7 0.0 1.7 7.5 0.0 2.6 3 0 0 3 3 3 2 Haspin like kinase domain Herpes_gE PF02480.16 RLN67568.1 - 0.0048 15.7 0.0 0.066 12.0 0.0 2.2 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E DUF4755 PF15947.5 RLN67568.1 - 0.0081 16.1 0.0 6 6.8 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4755) LRR_9 PF14580.6 RLN67568.1 - 0.0096 15.4 0.2 0.34 10.4 0.1 2.8 2 1 1 3 3 3 1 Leucine-rich repeat LapA_dom PF06305.11 RLN67568.1 - 0.015 15.1 4.9 0.45 10.4 0.3 3.1 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Kdo PF06293.14 RLN67568.1 - 0.015 14.6 0.0 5.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family TMEM154 PF15102.6 RLN67568.1 - 0.016 15.1 0.1 0.62 10.0 0.0 3.2 3 1 0 3 3 2 0 TMEM154 protein family DUF2561 PF10812.8 RLN67568.1 - 0.017 15.2 1.8 2 8.4 1.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2561) DUF4381 PF14316.6 RLN67568.1 - 0.023 14.9 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Pox_ser-thr_kin PF05445.11 RLN67568.1 - 0.076 12.0 0.2 10 5.0 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Nuc_sug_transp PF04142.15 RLN67569.1 - 8.4e-32 110.6 19.0 1e-31 110.3 19.0 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 RLN67569.1 - 0.00021 21.5 28.1 0.029 14.6 16.0 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 RLN67569.1 - 0.0017 17.7 20.5 0.004 16.4 20.5 1.7 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 RLN67569.1 - 0.002 17.4 22.1 0.0072 15.6 22.1 1.7 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport DUF983 PF06170.12 RLN67569.1 - 1.1 9.6 0.0 1.1 9.6 0.0 3.5 3 1 0 4 4 4 0 Protein of unknown function (DUF983) GFO_IDH_MocA PF01408.22 RLN67570.1 - 1.4e-06 29.1 0.0 2.8e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 RLN67570.1 - 3.2e-05 23.9 0.0 6.7e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Gp_dh_N PF00044.24 RLN67570.1 - 0.059 13.7 0.0 0.21 11.9 0.0 1.9 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Glyco_transf_20 PF00982.21 RLN67571.1 - 1.4e-55 188.9 0.0 1.3e-43 149.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 RLN67571.1 - 1.8e-34 118.9 0.1 4e-34 117.8 0.0 1.6 2 0 0 2 2 2 1 Trehalose-phosphatase DDE_1 PF03184.19 RLN67573.1 - 8.6e-07 28.8 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RabGAP-TBC PF00566.18 RLN67600.1 - 0.0038 16.9 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RINT1_TIP1 PF04437.13 RLN67600.1 - 0.014 14.3 0.5 0.023 13.6 0.5 1.4 1 0 0 1 1 1 0 RINT-1 / TIP-1 family Pup PF05639.11 RLN67600.1 - 1.1 10.3 5.8 2.4 9.2 0.0 3.0 3 0 0 3 3 3 0 Pup-like protein Mut7-C PF01927.16 RLN67601.1 - 1.7e-31 109.3 0.1 3.1e-31 108.4 0.1 1.4 1 0 0 1 1 1 1 Mut7-C RNAse domain tRNA_edit PF04073.15 RLN67601.1 - 1.1e-08 35.2 0.0 2.3e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain DUF5615 PF18480.1 RLN67601.1 - 0.012 15.4 0.0 0.036 13.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) DUF1450 PF07293.11 RLN67601.1 - 0.018 14.9 0.0 0.018 14.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1450) Glyco_hydro_3 PF00933.21 RLN67653.1 - 3.5e-50 171.2 0.0 4.6e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN67653.1 - 2.6e-17 63.4 0.0 4.8e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain DDE_1 PF03184.19 RLN67659.1 - 1.4e-10 41.1 0.0 1.6e-10 40.9 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease CorA PF01544.18 RLN67664.1 - 0.0025 17.2 11.3 0.013 14.9 11.3 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2569 PF10754.9 RLN67664.1 - 0.0093 16.4 2.7 0.018 15.5 2.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2569) Adap_comp_sub PF00928.21 RLN67665.1 - 2.6e-16 59.8 0.0 2.9e-16 59.6 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family mit_SMPDase PF14724.6 RLN67666.1 - 1e-19 70.1 0.0 3.9e-19 68.2 0.0 1.9 1 1 0 1 1 1 1 Mitochondrial-associated sphingomyelin phosphodiesterase CorA PF01544.18 RLN67667.1 - 3.6e-06 26.5 10.3 2.6e-05 23.7 10.3 2.1 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein ADSL_C PF10397.9 RLN67668.1 - 4e-19 68.9 0.0 7.4e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Bromodomain PF00439.25 RLN67669.1 - 3.1e-13 49.6 0.0 6.9e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 RLN67669.1 - 0.025 14.5 2.2 0.028 14.3 0.9 1.7 2 0 0 2 2 2 0 PHD-finger TPR_1 PF00515.28 RLN67670.1 - 4.2e-21 73.8 0.7 8.1e-08 31.8 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 RLN67670.1 - 4.5e-21 73.2 4.4 3.1e-06 26.9 0.0 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 RLN67670.1 - 2.4e-19 68.7 1.1 3.1e-08 33.1 0.0 5.1 2 2 3 5 5 5 4 TPR repeat TPR_16 PF13432.6 RLN67670.1 - 1.5e-15 57.5 15.9 6.5e-08 33.1 0.5 3.9 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 RLN67670.1 - 1.2e-13 51.1 8.4 2.8e-08 33.9 0.6 4.0 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 RLN67670.1 - 5.4e-13 49.3 3.5 1.6e-06 28.5 0.1 3.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 RLN67670.1 - 2.7e-12 46.1 1.2 0.00011 22.3 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN67670.1 - 2.5e-10 40.3 11.3 0.0082 16.9 0.1 5.7 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN67670.1 - 3e-09 36.2 5.7 0.012 15.6 0.1 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN67670.1 - 4.5e-09 36.4 0.8 8.8e-07 29.1 0.3 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 RLN67670.1 - 5e-09 35.9 3.0 0.72 10.6 0.8 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN67670.1 - 9.8e-09 34.8 0.3 0.0025 17.9 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN67670.1 - 5.5e-08 32.4 11.7 0.022 14.6 0.3 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 RLN67670.1 - 6.6e-07 29.6 8.7 1 10.2 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat BTAD PF03704.17 RLN67670.1 - 3.6e-06 27.5 7.2 1.1e-05 25.9 0.8 3.2 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_15 PF13429.6 RLN67670.1 - 4.6e-06 26.1 1.6 4.5e-05 22.8 1.7 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN67670.1 - 7e-06 26.1 10.2 0.083 13.1 0.2 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_20 PF14561.6 RLN67670.1 - 9.3e-06 25.9 2.6 0.00031 21.0 0.3 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 RLN67670.1 - 0.0012 18.3 0.6 2.2 7.8 0.0 3.7 3 0 0 3 3 3 1 SHNi-TPR TPR_21 PF09976.9 RLN67670.1 - 0.0024 17.6 1.0 3.4 7.3 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat-like domain TPR_5 PF12688.7 RLN67670.1 - 0.0037 17.5 3.2 0.063 13.5 1.0 3.0 2 1 1 3 3 3 2 Tetratrico peptide repeat DUF3856 PF12968.7 RLN67670.1 - 0.0043 17.1 0.1 6.4 6.8 0.0 3.3 2 1 1 3 3 3 1 Domain of Unknown Function (DUF3856) MIT PF04212.18 RLN67670.1 - 0.0069 16.4 3.9 8.6 6.5 0.0 4.6 4 1 1 5 5 3 0 MIT (microtubule interacting and transport) domain Wzy_C_2 PF11846.8 RLN67670.1 - 0.016 15.1 0.1 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal BRCA-2_OB1 PF09103.10 RLN67670.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Lyase_1 PF00206.20 RLN67671.1 - 5.7e-12 45.7 0.1 7.4e-12 45.3 0.1 1.2 1 0 0 1 1 1 1 Lyase WW PF00397.26 RLN67672.1 - 2.5e-08 33.9 1.1 5.2e-08 32.8 1.1 1.5 1 0 0 1 1 1 1 WW domain GAF PF01590.26 RLN67673.1 - 7.7e-36 123.7 0.0 8.7e-18 65.2 0.0 2.2 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 RLN67673.1 - 1.7e-21 76.9 0.0 2.5e-13 50.5 0.0 2.2 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 RLN67673.1 - 9.7e-13 48.6 0.0 1.4e-05 25.4 0.0 2.3 2 0 0 2 2 2 2 GAF domain dCache_1 PF02743.18 RLN67673.1 - 0.0014 18.5 0.2 0.092 12.5 0.1 2.3 2 0 0 2 2 2 1 Cache domain DUF2853 PF11015.8 RLN67673.1 - 0.023 15.4 0.1 0.2 12.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2853) Sigma54_CBD PF04963.13 RLN67673.1 - 0.069 13.0 0.0 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 factor, core binding domain Lpp-LpqN PF10738.9 RLN67674.1 - 0.018 14.5 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Probable lipoprotein LpqN Glyco_transf_41 PF13844.6 RLN67675.1 - 5.2e-10 38.4 0.0 5.8e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 41 Glyco_trans_1_4 PF13692.6 RLN67675.1 - 1.4e-05 25.6 0.0 1.7e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 RLN67675.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 bZIP_1 PF00170.21 RLN67698.1 - 0.0059 16.7 2.0 0.0093 16.0 2.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RLN67698.1 - 0.0078 16.3 3.3 0.013 15.6 3.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper TPR_2 PF07719.17 RLN67754.1 - 0.019 15.0 0.0 0.061 13.5 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN67754.1 - 0.047 13.5 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Motile_Sperm PF00635.26 RLN67755.1 - 1.4e-20 73.2 0.0 7.9e-10 38.6 0.0 2.5 2 1 0 2 2 2 2 MSP (Major sperm protein) domain START PF01852.19 RLN67756.1 - 1.2e-21 77.1 0.0 1.5e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 START domain LMWSLP_N PF12211.8 RLN67756.1 - 0.071 12.7 0.1 0.086 12.5 0.1 1.1 1 0 0 1 1 1 0 Low molecular weight S layer protein N terminal BRCT PF00533.26 RLN67757.1 - 2.8e-10 40.4 0.0 6.6e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 RLN67757.1 - 9.2e-08 32.4 0.0 2.3e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 RLN67757.1 - 9.3e-06 25.5 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 RLN67757.1 - 0.0006 19.7 0.1 0.0035 17.3 0.1 2.1 1 1 0 1 1 1 1 twin BRCT domain BRCT_3 PF18428.1 RLN67757.1 - 0.19 11.8 0.0 0.44 10.6 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Pex19 PF04614.12 RLN67758.1 - 3.7e-19 69.5 32.9 1.2e-16 61.3 32.9 3.1 1 1 0 1 1 1 1 Pex19 protein family SRP54_N PF02881.19 RLN67758.1 - 0.0015 18.7 0.1 0.015 15.5 0.0 2.6 2 1 0 2 2 2 1 SRP54-type protein, helical bundle domain ZYG-11_interact PF05884.12 RLN67758.1 - 0.018 14.5 0.2 0.054 12.9 0.1 1.9 1 1 1 2 2 2 0 Interactor of ZYG-11 SesA PF17107.5 RLN67758.1 - 0.074 13.2 0.7 0.66 10.2 0.7 2.4 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases SCAB-ABD PF16711.5 RLN67758.1 - 0.077 12.9 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 Actin-binding domain of plant-specific actin-binding protein Tape_meas_lam_C PF09718.10 RLN67758.1 - 0.2 11.8 2.8 0.6 10.3 2.8 1.8 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) TM231 PF10149.9 RLN67758.1 - 0.28 10.5 2.4 0.86 8.9 2.2 1.8 1 1 0 1 1 1 0 Transmembrane protein 231 Tyrosinase PF00264.20 RLN67774.1 - 4.3e-45 154.7 0.1 1.3e-22 81.1 0.0 2.7 2 0 0 2 2 2 2 Common central domain of tyrosinase Lectin_C PF00059.21 RLN67774.1 - 0.0079 16.9 0.2 1 10.1 0.0 3.0 2 0 0 2 2 2 1 Lectin C-type domain Pertussis_S2S3 PF02918.15 RLN67774.1 - 0.022 14.7 0.0 4.7 7.2 0.0 2.7 2 0 0 2 2 2 0 Pertussis toxin, subunit 2 and 3, C-terminal domain TraW_N PF12477.8 RLN67774.1 - 1 9.4 9.5 39 4.4 0.0 4.2 4 0 0 4 4 4 0 Sex factor F TraW protein N terminal ABC2_membrane PF01061.24 RLN67776.1 - 7.1e-41 139.9 19.6 9.6e-41 139.5 19.6 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN67776.1 - 4.6e-28 98.4 0.0 7.7e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN67776.1 - 1.1e-07 32.0 0.1 0.0077 16.1 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN67776.1 - 0.00027 20.9 0.0 0.00048 20.1 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase DUF3902 PF13042.6 RLN67776.1 - 0.00088 18.9 0.4 0.0022 17.6 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3902) AAA_29 PF13555.6 RLN67776.1 - 0.0013 18.4 0.2 0.0029 17.3 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN67776.1 - 0.003 18.0 0.0 0.0051 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 RLN67776.1 - 0.0036 16.5 15.8 0.0036 16.5 15.8 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_23 PF13476.6 RLN67776.1 - 0.0054 17.2 0.0 0.01 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 RLN67776.1 - 0.0076 15.7 0.6 0.74 9.2 0.2 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RLN67776.1 - 0.038 14.3 0.1 0.45 10.8 0.0 2.3 1 1 1 2 2 2 0 AAA domain Rad17 PF03215.15 RLN67776.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 RLN67776.1 - 0.2 11.8 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Oxidored_FMN PF00724.20 RLN67777.1 - 5.9e-81 272.4 0.0 6.6e-81 272.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 RLN67777.1 - 0.013 15.0 0.0 7.1 6.0 0.0 3.1 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel Clathrin-link PF09268.10 RLN67777.1 - 0.15 11.4 0.1 0.15 11.4 0.1 1.6 2 0 0 2 2 2 0 Clathrin, heavy-chain linker TPR_MLP1_2 PF07926.12 RLN67778.1 - 2.3e-16 60.0 31.1 2.3e-16 60.0 31.1 16.4 7 3 7 15 15 15 9 TPR/MLP1/MLP2-like protein TFA2_Winged_2 PF18121.1 RLN67778.1 - 0.52 10.0 6.3 0.33 10.7 0.1 3.6 3 0 0 3 3 3 0 TFA2 Winged helix domain 2 ZapB PF06005.12 RLN67779.1 - 0.0067 16.8 13.8 27 5.3 10.0 3.0 2 1 0 2 2 2 0 Cell division protein ZapB DUF3122 PF11320.8 RLN67779.1 - 0.012 15.7 0.5 0.025 14.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3122) DUF5340 PF17275.2 RLN67779.1 - 0.019 15.1 2.8 0.17 12.0 0.2 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5340) CCDC144C PF14915.6 RLN67779.1 - 0.025 13.7 2.9 0.046 12.8 2.9 1.4 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region bZIP_1 PF00170.21 RLN67779.1 - 0.053 13.6 3.4 4 7.6 0.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor UPF0242 PF06785.11 RLN67779.1 - 0.054 13.6 0.9 0.11 12.6 0.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GIT_CC PF16559.5 RLN67779.1 - 0.1 12.5 0.1 0.1 12.5 0.1 1.9 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Uso1_p115_C PF04871.13 RLN67779.1 - 0.11 12.8 6.1 13 6.2 4.8 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF812 PF05667.11 RLN67779.1 - 0.16 10.8 5.3 0.2 10.5 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) HALZ PF02183.18 RLN67779.1 - 0.16 12.2 0.8 6.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 RLN67779.1 - 0.21 11.7 4.5 6.2 7.0 1.0 2.5 2 0 0 2 2 2 0 Basic region leucine zipper Leu_zip PF15294.6 RLN67779.1 - 0.33 10.4 3.5 0.1 12.1 0.6 1.5 2 0 0 2 2 2 0 Leucine zipper Cnn_1N PF07989.11 RLN67779.1 - 0.83 9.8 3.3 28 4.9 3.3 2.5 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 SlyX PF04102.12 RLN67779.1 - 0.97 10.1 4.7 1.6 9.4 0.1 2.6 1 1 1 2 2 2 0 SlyX YabA PF06156.13 RLN67779.1 - 1 10.0 6.0 3 8.5 0.8 2.7 2 1 1 3 3 3 0 Initiation control protein YabA Shugoshin_N PF07558.11 RLN67779.1 - 1.3 8.9 4.1 9.3 6.2 1.0 2.4 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region ATG16 PF08614.11 RLN67779.1 - 1.8 8.8 10.8 2.3 8.4 9.8 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF724 PF05266.14 RLN67779.1 - 2.3 8.0 4.5 0.64 9.8 1.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DivIC PF04977.15 RLN67779.1 - 3 7.7 7.5 6 6.7 0.4 2.7 1 1 1 2 2 2 0 Septum formation initiator Sugar_tr PF00083.24 RLN67780.1 - 2.2e-78 264.2 23.3 2.7e-78 263.9 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN67780.1 - 3.4e-19 69.0 27.3 3.4e-19 69.0 27.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN67781.1 - 3.8e-82 276.5 27.3 4.5e-82 276.3 27.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN67781.1 - 2.6e-20 72.6 29.6 2.6e-20 72.6 29.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily HlyIII PF03006.20 RLN67781.1 - 2.4 7.8 27.1 0.27 10.9 3.1 4.1 3 2 1 4 4 4 0 Haemolysin-III related 60KD_IMP PF02096.20 RLN67781.1 - 8.7 6.2 9.2 2.9 7.8 0.1 3.3 2 2 1 3 3 3 0 60Kd inner membrane protein Sugar_tr PF00083.24 RLN67782.1 - 6.7e-84 282.3 26.3 8e-84 282.1 26.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN67782.1 - 3.7e-23 82.0 29.8 3.7e-23 82.0 29.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC2_membrane PF01061.24 RLN67784.1 - 4.1e-36 124.4 20.7 6.4e-36 123.7 20.7 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN67784.1 - 5.5e-27 94.9 0.0 9.7e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN67784.1 - 1.2e-07 31.9 0.1 0.0091 15.8 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN67784.1 - 0.00058 19.8 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN67784.1 - 0.0013 18.5 0.1 0.0027 17.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN67784.1 - 0.0025 18.2 0.1 0.0045 17.4 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 RLN67784.1 - 0.0051 17.3 0.0 0.0096 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 RLN67784.1 - 0.01 15.3 0.8 0.74 9.2 0.1 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RLN67784.1 - 0.036 14.4 0.0 0.59 10.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 RLN67784.1 - 0.1 11.7 18.1 0.15 11.1 18.1 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1462 PF07315.11 RLN67784.1 - 0.11 12.7 0.0 1.7 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1462) ABC2_membrane PF01061.24 RLN67785.1 - 6.7e-52 176.0 62.2 3.6e-28 98.4 19.2 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN67785.1 - 9.1e-26 91.0 0.1 3.9e-13 50.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN67785.1 - 4.3e-11 43.2 0.1 5e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 RLN67785.1 - 2.9e-05 23.3 45.2 9e-05 21.7 15.7 3.3 2 2 1 3 3 3 2 ABC-2 family transporter protein Pkinase_Tyr PF07714.17 RLN67788.1 - 3.1e-26 92.2 0.0 4.2e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN67788.1 - 6.2e-25 88.1 0.0 8e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain OrfB_Zn_ribbon PF07282.11 RLN67790.1 - 1.2e-05 25.2 5.6 0.045 13.7 0.9 2.6 1 1 0 2 2 2 2 Putative transposase DNA-binding domain DUF1206 PF06724.11 RLN67791.1 - 0.0012 18.8 0.2 0.0012 18.8 0.2 3.3 4 1 0 4 4 4 1 Domain of Unknown Function (DUF1206) Ribosomal_L28 PF00830.19 RLN67792.1 - 1.7e-18 66.5 0.8 2.7e-18 65.9 0.8 1.3 1 0 0 1 1 1 1 Ribosomal L28 family Ank_2 PF12796.7 RLN67794.1 - 4.3e-44 149.0 12.8 3.3e-06 27.6 0.7 11.8 10 5 1 12 12 12 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN67794.1 - 7.6e-38 128.4 15.2 2.8e-05 24.6 0.1 14.5 11 5 5 16 16 16 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN67794.1 - 3e-28 97.5 19.6 2.4e-06 27.7 0.1 12.7 14 3 2 16 16 16 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN67794.1 - 8.9e-27 90.2 15.4 0.059 13.9 0.0 16.1 17 0 0 17 17 17 7 Ankyrin repeat Ank PF00023.30 RLN67794.1 - 1.3e-17 63.3 32.2 0.025 15.0 0.4 15.4 18 1 1 19 19 19 5 Ankyrin repeat LANC_like PF05147.13 RLN67794.1 - 0.12 10.9 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein 5_nucleotid PF05761.14 RLN67859.1 - 7.5e-76 255.9 0.1 1.5e-55 188.9 0.0 2.6 1 1 1 2 2 2 2 5' nucleotidase family PCI PF01399.27 RLN67861.1 - 4.1e-15 56.2 1.2 4.1e-15 56.2 1.2 2.0 2 0 0 2 2 2 1 PCI domain TPR_7 PF13176.6 RLN67861.1 - 0.0011 18.8 2.0 3.4 7.9 0.1 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat Malectin_like PF12819.7 RLN67861.1 - 0.0082 15.4 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Malectin-like domain CSN8_PSD8_EIF3K PF10075.9 RLN67861.1 - 0.074 13.0 0.3 0.19 11.7 0.3 1.7 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family TPR_14 PF13428.6 RLN67861.1 - 0.085 13.7 4.7 5.7 8.0 0.3 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN67861.1 - 0.59 10.5 4.4 7.2 7.0 1.3 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 RLN67862.1 - 3.2e-24 85.5 39.0 1e-16 60.8 7.8 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN67862.1 - 3.7e-13 49.1 1.1 3.7e-13 49.1 1.1 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 RLN67862.1 - 2.1e-08 32.9 17.2 0.0026 16.1 3.9 3.2 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family DUF4231 PF14015.6 RLN67880.1 - 0.0038 17.7 0.4 0.083 13.4 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4231) YwiC PF14256.6 RLN67880.1 - 0.004 17.4 4.0 0.004 17.4 4.0 2.2 1 1 1 2 2 2 1 YwiC-like protein DUF1129 PF06570.11 RLN67880.1 - 6.7 6.1 7.3 2.7e+02 0.9 7.3 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) adh_short PF00106.25 RLN67881.1 - 1.2e-42 145.7 0.1 1.6e-42 145.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN67881.1 - 6e-25 88.2 0.0 8.2e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN67881.1 - 5.1e-09 36.3 0.0 7.3e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 RLN67881.1 - 0.0062 16.4 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 RLN67881.1 - 0.028 13.8 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 RLN67881.1 - 0.058 13.3 0.1 0.082 12.8 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 RLN67881.1 - 0.063 12.7 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 RLN67881.1 - 0.13 11.3 0.1 0.18 10.9 0.1 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein ApbA PF02558.16 RLN67881.1 - 0.16 11.6 0.2 1.4 8.6 0.0 2.1 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA Copine PF07002.16 RLN67882.1 - 4.9e-27 94.8 0.0 8.6e-27 94.0 0.0 1.4 2 0 0 2 2 2 1 Copine Crp PF00325.20 RLN67882.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family G10 PF01125.17 RLN67952.1 - 2.8e-11 43.4 1.0 2.8e-11 43.4 1.0 1.8 2 1 0 2 2 2 1 G10 protein BUD22 PF09073.10 RLN67952.1 - 0.2 11.0 22.5 0.22 10.8 22.5 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 RLN67952.1 - 0.64 8.3 15.8 0.75 8.0 15.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF789 PF05623.12 RLN67952.1 - 1.7 8.2 5.8 2.3 7.8 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF789) Cwf_Cwc_15 PF04889.12 RLN67952.1 - 5.4 6.7 22.6 6.7 6.4 22.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Steroid_dh PF02544.16 RLN67954.1 - 3.1e-15 56.5 0.3 6.8e-15 55.3 0.2 1.7 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 RLN67954.1 - 0.0042 17.5 0.1 0.0042 17.5 0.1 2.6 4 0 0 4 4 4 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 RLN67954.1 - 0.0058 15.4 0.3 0.0058 15.4 0.3 1.6 2 0 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family AIM24 PF01987.17 RLN67979.1 - 5.3e-47 160.2 0.4 6.4e-47 160.0 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Ribosomal_L37ae PF01780.19 RLN67982.1 - 8.9e-40 134.7 6.4 1e-39 134.5 6.4 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Vps39_2 PF10367.9 RLN67982.1 - 0.029 14.8 0.1 0.035 14.5 0.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Zn_Tnp_IS1595 PF12760.7 RLN67982.1 - 0.04 13.9 2.2 0.075 13.0 2.2 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.15 RLN67982.1 - 0.81 9.8 9.3 0.96 9.5 0.4 2.7 2 1 1 3 3 3 0 BED zinc finger zf-H2C2_2 PF13465.6 RLN67982.1 - 4.5 7.9 7.7 13 6.4 0.8 2.6 2 1 1 3 3 3 0 Zinc-finger double domain RCC1 PF00415.18 RLN67983.1 - 8.9e-32 109.5 31.6 1.1e-10 41.9 0.3 10.1 9 2 0 9 9 9 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN67983.1 - 8.2e-30 102.0 37.2 1.7e-06 27.7 1.9 8.1 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat EF-hand_7 PF13499.6 RLN67983.1 - 1.8e-12 47.5 3.8 3.2e-09 37.1 0.3 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN67983.1 - 2.9e-12 45.2 5.4 1.1e-06 27.7 0.3 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RLN67983.1 - 1e-11 43.8 8.6 3.1e-05 23.6 1.4 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 RLN67983.1 - 6.5e-10 38.7 1.6 1.7e-06 27.8 0.0 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN67983.1 - 1.8e-05 24.0 11.1 7.7e-05 22.0 1.0 3.8 4 0 0 4 4 4 1 EF hand EF-hand_10 PF14788.6 RLN67983.1 - 0.00043 20.1 0.0 0.0014 18.4 0.0 1.9 1 0 0 1 1 1 1 EF hand Asp-B-Hydro_N PF05279.11 RLN67983.1 - 0.36 10.9 0.0 0.36 10.9 0.0 2.4 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region 2-Hacid_dh_C PF02826.19 RLN67984.1 - 1.3e-50 171.2 0.0 2.1e-50 170.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 RLN67984.1 - 9.8e-25 86.8 0.0 1.5e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 RLN67984.1 - 7.3e-06 25.6 0.0 2e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 ACT domain NAD_binding_2 PF03446.15 RLN67984.1 - 0.00086 19.5 0.8 0.0023 18.1 0.4 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 RLN67984.1 - 0.002 18.2 0.2 0.0036 17.4 0.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 RLN67984.1 - 0.091 12.6 0.3 0.32 10.9 0.3 2.0 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-C2H2 PF00096.26 RLN68059.1 - 5.4e-10 39.2 16.7 0.086 13.3 1.7 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN68059.1 - 7.7e-09 35.7 23.8 0.087 13.7 0.7 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_2 PF12756.7 RLN68059.1 - 3.1e-05 24.2 9.3 0.75 10.2 0.1 4.5 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 RLN68059.1 - 0.00019 21.3 14.7 0.53 10.3 0.2 4.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2HE PF16278.5 RLN68059.1 - 0.00019 21.8 10.3 0.052 14.0 0.0 4.4 3 1 1 4 4 4 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 RLN68059.1 - 0.0004 20.6 3.0 0.34 11.2 0.2 3.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-ribbon_3 PF13248.6 RLN68059.1 - 0.0028 17.0 6.6 0.47 9.9 0.0 4.4 4 0 0 4 4 4 1 zinc-ribbon domain ADK_lid PF05191.14 RLN68059.1 - 0.0051 16.8 6.1 1.5 8.9 0.3 3.9 2 2 0 2 2 2 2 Adenylate kinase, active site lid zf-met PF12874.7 RLN68059.1 - 0.0066 16.8 8.6 5.5 7.5 0.2 5.0 4 0 0 4 4 4 1 Zinc-finger of C2H2 type XPA_N PF01286.18 RLN68059.1 - 0.021 14.9 4.1 31 4.7 0.0 4.3 4 0 0 4 4 4 0 XPA protein N-terminal HTH_35 PF13693.6 RLN68059.1 - 0.032 14.3 0.1 0.092 12.8 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding zf-BED PF02892.15 RLN68059.1 - 0.052 13.6 6.8 1.2 9.2 0.1 4.1 4 0 0 4 4 4 0 BED zinc finger zf-LYAR PF08790.11 RLN68059.1 - 0.11 12.4 4.6 5.4 7.0 0.1 3.9 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 RLN68059.1 - 0.29 10.8 7.9 11 5.7 0.2 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger DUF2256 PF10013.9 RLN68059.1 - 0.45 10.7 13.2 2.2 8.5 0.4 4.4 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_11 PF16622.5 RLN68059.1 - 0.45 10.3 0.1 0.45 10.3 0.1 4.6 5 0 0 5 5 4 0 zinc-finger C2H2-type CpXC PF14353.6 RLN68059.1 - 0.56 10.3 14.3 0.82 9.7 3.7 4.5 3 2 1 4 4 4 0 CpXC protein zinc_ribbon_4 PF13717.6 RLN68059.1 - 0.57 10.1 14.8 12 5.9 1.1 4.6 4 0 0 4 4 4 0 zinc-ribbon domain FYDLN_acid PF09538.10 RLN68059.1 - 1.3 9.7 19.8 2.5 8.8 0.8 5.0 3 3 1 4 4 3 0 Protein of unknown function (FYDLN_acid) Rad50_zn_hook PF04423.14 RLN68059.1 - 1.6 8.6 4.5 8 6.4 0.1 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif DZR PF12773.7 RLN68059.1 - 2.6 8.1 18.6 5.4 7.1 6.0 3.5 2 2 0 2 2 2 0 Double zinc ribbon zf-H2C2_2 PF13465.6 RLN68059.1 - 3.3 8.3 16.6 2.1 8.9 0.2 5.0 4 0 0 4 4 4 0 Zinc-finger double domain zf_C2H2_10 PF18414.1 RLN68059.1 - 3.3 7.3 6.9 14 5.3 0.1 3.0 3 0 0 3 3 2 0 C2H2 type zinc-finger GAGA PF09237.11 RLN68059.1 - 5.8 6.8 12.1 30 4.5 0.2 4.5 4 0 0 4 4 4 0 GAGA factor zinc_ribbon_2 PF13240.6 RLN68059.1 - 9.5 6.1 13.4 8.4 6.3 0.1 4.4 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 RLN68060.1 - 7.5e-12 45.0 20.3 0.004 17.9 0.2 5.5 5 0 0 5 5 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RLN68060.1 - 9.9e-12 44.6 14.0 0.0011 18.9 0.3 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 RLN68060.1 - 1.3e-11 44.3 15.7 0.00048 20.4 0.6 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type OrfB_Zn_ribbon PF07282.11 RLN68060.1 - 7.6e-08 32.2 0.5 7.6e-08 32.2 0.5 4.5 3 1 0 3 3 3 1 Putative transposase DNA-binding domain zf-C2H2_11 PF16622.5 RLN68060.1 - 9.6e-07 28.5 6.8 0.035 13.9 0.2 3.7 3 0 0 3 3 3 2 zinc-finger C2H2-type zf_UBZ PF18439.1 RLN68060.1 - 4.2e-05 23.0 5.1 1 9.0 0.0 4.1 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 RLN68060.1 - 0.0001 22.6 4.5 1.8 8.9 0.4 4.4 3 1 1 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 RLN68060.1 - 0.00017 21.8 8.5 1.6 9.3 1.2 4.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2HC_2 PF13913.6 RLN68060.1 - 0.00024 20.9 12.1 0.46 10.5 0.3 3.9 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 RLN68060.1 - 0.00028 21.1 7.2 2.6 8.4 0.2 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding XPA_N PF01286.18 RLN68060.1 - 0.00039 20.4 5.4 5.4 7.1 0.2 4.0 3 0 0 3 3 3 2 XPA protein N-terminal zf-BED PF02892.15 RLN68060.1 - 0.00094 19.2 9.4 0.29 11.2 0.1 4.0 5 0 0 5 5 3 2 BED zinc finger CpXC PF14353.6 RLN68060.1 - 0.0022 18.0 10.1 0.89 9.6 3.7 4.4 3 1 1 4 4 4 2 CpXC protein DUF2256 PF10013.9 RLN68060.1 - 0.005 16.9 13.5 0.75 10.0 0.2 4.8 4 0 0 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-met PF12874.7 RLN68060.1 - 0.0056 17.0 3.5 12 6.4 0.2 3.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type GAGA PF09237.11 RLN68060.1 - 0.018 14.9 0.0 0.88 9.4 0.0 2.7 2 0 0 2 2 2 0 GAGA factor zf-ribbon_3 PF13248.6 RLN68060.1 - 0.054 12.9 13.8 1.5 8.3 0.4 4.2 4 0 0 4 4 4 0 zinc-ribbon domain HypA PF01155.19 RLN68060.1 - 0.089 12.8 6.3 1.4 8.9 0.9 3.3 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ADK_lid PF05191.14 RLN68060.1 - 0.11 12.5 7.2 0.47 10.5 0.1 3.5 2 1 1 3 3 3 0 Adenylate kinase, active site lid Nop10p PF04135.12 RLN68060.1 - 0.78 9.8 5.0 44 4.2 0.1 3.7 3 0 0 3 3 3 0 Nucleolar RNA-binding protein, Nop10p family zf-C2H2_9 PF16293.5 RLN68060.1 - 0.83 9.5 2.5 23 4.9 0.0 3.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_4 PF13717.6 RLN68060.1 - 0.96 9.4 17.0 9.2 6.3 1.0 4.6 4 0 0 4 4 4 0 zinc-ribbon domain NinG PF05766.12 RLN68060.1 - 2.6 8.0 9.7 0.11 12.5 2.9 2.2 3 0 0 3 3 2 0 Bacteriophage Lambda NinG protein YhfH PF14149.6 RLN68060.1 - 2.8 8.0 17.6 1 9.4 0.7 3.9 4 0 0 4 4 4 0 YhfH-like protein zf_ZIC PF18366.1 RLN68060.1 - 5.5 7.2 6.2 9 6.5 0.0 3.9 5 0 0 5 5 5 0 Zic proteins zinc finger domain Peroxidase_2 PF01328.17 RLN68062.1 - 2.1e-53 181.7 0.0 2.5e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 HemY_N PF07219.13 RLN68063.1 - 0.38 11.0 4.1 0.36 11.1 0.2 3.0 2 0 0 2 2 2 0 HemY protein N-terminus zf-C2H2 PF00096.26 RLN68064.1 - 9.8e-13 47.8 19.2 0.00035 20.9 0.4 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN68064.1 - 1.2e-10 41.2 13.0 0.0053 17.5 0.3 4.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RLN68064.1 - 1.8e-07 31.0 11.1 0.022 14.7 0.1 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf_UBZ PF18439.1 RLN68064.1 - 1.7e-05 24.3 5.2 0.59 9.8 0.0 4.8 4 0 0 4 4 4 1 Ubiquitin-Binding Zinc Finger Lzipper-MIP1 PF14389.6 RLN68064.1 - 0.00075 19.8 0.2 1.1 9.5 0.0 3.5 3 0 0 3 3 3 1 Leucine-zipper of ternary complex factor MIP1 zf-C2HC_2 PF13913.6 RLN68064.1 - 0.0029 17.4 8.2 1.3 9.1 0.7 3.6 3 0 0 3 3 3 1 zinc-finger of a C2HC-type DUF1192 PF06698.11 RLN68064.1 - 0.034 14.2 1.3 0.18 11.9 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) YhfH PF14149.6 RLN68064.1 - 0.034 14.1 6.3 2.7 8.0 0.2 3.6 3 0 0 3 3 3 0 YhfH-like protein ADK_lid PF05191.14 RLN68064.1 - 0.039 13.9 5.9 0.035 14.1 1.0 3.2 2 2 1 3 3 3 0 Adenylate kinase, active site lid zf-C2H2_jaz PF12171.8 RLN68064.1 - 0.075 13.4 4.5 8 6.9 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Mer2 PF09074.10 RLN68064.1 - 0.11 12.2 2.0 0.8 9.5 2.0 2.3 1 1 0 1 1 1 0 Mer2 zf-LYAR PF08790.11 RLN68064.1 - 0.12 12.4 12.6 5 7.1 0.1 4.6 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-BED PF02892.15 RLN68064.1 - 0.12 12.4 5.0 2.5 8.2 0.2 3.2 2 1 1 3 3 3 0 BED zinc finger zf-C2H2_2 PF12756.7 RLN68064.1 - 0.19 12.1 13.4 13 6.1 0.0 4.4 2 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 RLN68064.1 - 0.35 11.0 18.3 42 4.4 13.1 3.9 2 1 0 2 2 2 0 FYVE zinc finger DUF2256 PF10013.9 RLN68064.1 - 0.61 10.3 15.9 5.8 7.1 0.8 4.5 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-met PF12874.7 RLN68064.1 - 0.73 10.3 12.2 32 5.1 0.5 4.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type HR1 PF02185.16 RLN68064.1 - 1 9.5 3.9 1.8 8.8 0.4 2.9 2 0 0 2 2 2 0 Hr1 repeat DZR PF12773.7 RLN68064.1 - 1.2 9.3 22.5 0.046 13.7 2.9 3.4 1 1 1 2 2 2 0 Double zinc ribbon DUF3138 PF11336.8 RLN68064.1 - 3.5 6.1 6.4 2.3 6.8 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) CENP-O PF09496.10 RLN68064.1 - 3.5 7.5 7.6 9.3 6.2 1.3 3.1 2 1 1 3 3 3 0 Cenp-O kinetochore centromere component zf-C2H2_11 PF16622.5 RLN68064.1 - 4.4 7.2 16.6 5.5 6.9 0.1 4.6 4 0 0 4 4 4 0 zinc-finger C2H2-type Jnk-SapK_ap_N PF09744.9 RLN68064.1 - 5.7 7.2 12.4 0.11 12.7 0.7 3.5 4 0 0 4 4 3 0 JNK_SAPK-associated protein-1 zf-C2H2_9 PF16293.5 RLN68064.1 - 6 6.8 5.9 4.1 7.3 0.1 3.1 3 0 0 3 3 2 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_4 PF13717.6 RLN68064.1 - 6 6.9 15.0 6.5 6.8 0.2 4.5 4 0 0 4 4 4 0 zinc-ribbon domain Glyco_hydro_47 PF01532.20 RLN68065.1 - 2e-110 369.9 0.1 6.3e-73 246.2 0.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 HTH_Tnp_Tc5 PF03221.16 RLN68066.1 - 4.5e-10 39.4 0.0 1.3e-09 37.9 0.0 1.7 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DUF1525 PF07511.11 RLN68066.1 - 0.029 14.5 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) NACHT PF05729.12 RLN68067.1 - 6.6e-08 32.7 0.0 5.7e-07 29.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 RLN68067.1 - 4.9e-07 30.3 0.0 4.9e-07 30.3 0.0 3.5 4 1 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 RLN68067.1 - 1.3e-05 25.5 0.1 0.00011 22.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF4449 PF14613.6 RLN68067.1 - 0.025 14.7 4.5 0.095 12.8 4.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) KAP_NTPase PF07693.14 RLN68067.1 - 1.1 8.4 0.0 1.1 8.4 0.0 3.3 4 1 1 5 5 5 0 KAP family P-loop domain MitMem_reg PF13012.6 RLN68068.1 - 6e-34 116.8 0.3 1e-33 116.1 0.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 RLN68068.1 - 4.1e-25 88.0 0.0 8.2e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF2937 PF11157.8 RLN68068.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) TRPM_tetra PF16519.5 RLN68068.1 - 0.19 11.9 0.8 3.9 7.7 0.1 2.5 2 0 0 2 2 2 0 Tetramerisation domain of TRPM Ank_2 PF12796.7 RLN68069.1 - 9.4e-24 83.8 0.1 4.4e-13 49.6 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 RLN68069.1 - 2.2e-19 68.9 6.7 1.1e-05 25.6 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 RLN68069.1 - 4e-19 66.7 0.5 0.00012 22.2 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 RLN68069.1 - 7.5e-19 67.5 3.3 4.7e-05 23.6 0.1 5.0 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN68069.1 - 1.2e-17 64.0 0.5 2.4e-07 31.1 0.1 4.2 2 2 1 3 3 3 3 Ankyrin repeats (many copies) PX PF00787.24 RLN68069.1 - 0.034 14.1 0.1 0.43 10.6 0.1 2.4 1 1 0 1 1 1 0 PX domain FYVE PF01363.21 RLN68070.1 - 0.00015 21.9 9.3 0.00037 20.6 9.3 1.7 1 0 0 1 1 1 1 FYVE zinc finger zf-CCCH PF00642.24 RLN68072.1 - 6.5e-10 38.7 2.7 2.4e-09 36.8 2.7 2.1 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.6 RLN68072.1 - 9.7e-07 29.0 5.6 3.8e-05 23.9 2.3 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 RLN68072.1 - 4.7e-06 26.5 7.9 4.8e-05 23.2 3.6 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf_CCCH_4 PF18345.1 RLN68072.1 - 1.2e-05 25.2 4.5 3.1e-05 23.9 4.5 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_3 PF13920.6 RLN68072.1 - 2.3e-05 24.2 6.9 5.8e-05 22.9 2.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN68072.1 - 6.1e-05 22.8 3.7 0.00031 20.6 3.7 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 RLN68072.1 - 0.00034 20.3 2.7 0.00034 20.3 2.7 2.2 2 0 0 2 2 1 1 CCCH-type zinc finger zf-RING_UBOX PF13445.6 RLN68072.1 - 0.0028 17.7 6.0 0.07 13.2 5.9 2.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 RLN68072.1 - 0.015 15.4 2.8 0.015 15.4 2.8 2.2 3 0 0 3 3 2 0 zinc RING finger of MSL2 zf-C3HC4_2 PF13923.6 RLN68072.1 - 0.09 12.6 12.8 0.059 13.2 6.7 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN68072.1 - 0.22 11.4 6.5 0.12 12.3 2.9 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Rtf2 PF04641.12 RLN68072.1 - 0.47 9.8 5.0 2 7.7 1.9 2.4 2 0 0 2 2 2 0 Rtf2 RING-finger zf-CCCH_2 PF14608.6 RLN68072.1 - 3.1 8.4 8.9 0.12 12.9 1.9 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-C3HC4_4 PF15227.6 RLN68072.1 - 5.3 7.3 12.5 4.9 7.4 4.9 2.9 3 0 0 3 3 2 0 zinc finger of C3HC4-type, RING zf-C2H2_jaz PF12171.8 RLN68072.1 - 7.9 6.9 10.6 3 8.2 2.0 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding TRP PF06011.12 RLN68073.1 - 7.9e-28 97.3 12.7 7.9e-28 97.3 12.7 1.9 2 1 0 2 2 2 1 Transient receptor potential (TRP) ion channel Pkinase_Tyr PF07714.17 RLN68073.1 - 0.00016 21.0 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ACT_4 PF13291.6 RLN68073.1 - 0.032 14.8 0.1 0.068 13.8 0.1 1.6 1 0 0 1 1 1 0 ACT domain ACT PF01842.25 RLN68073.1 - 0.08 12.7 0.1 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 ACT domain DUF2755 PF10954.8 RLN68073.1 - 0.4 10.6 4.9 0.17 11.8 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2755) DinB_2 PF12867.7 RLN68076.1 - 1.5e-05 25.5 0.9 2.2e-05 24.9 0.9 1.3 1 0 0 1 1 1 1 DinB superfamily Glutaredoxin PF00462.24 RLN68077.1 - 4.3e-22 78.1 0.0 5.7e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 RLN68077.1 - 0.00021 21.6 0.0 0.00029 21.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 RLN68077.1 - 0.00031 21.1 0.0 0.00038 20.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.6 RLN68077.1 - 0.00063 19.9 0.6 0.16 12.1 0.2 2.1 1 1 0 2 2 2 2 Thioredoxin DSBA PF01323.20 RLN68077.1 - 0.00069 19.4 0.5 0.49 10.1 0.1 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain GST_N_2 PF13409.6 RLN68077.1 - 0.018 15.3 0.0 0.024 14.9 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RLN68077.1 - 0.027 14.8 0.0 0.036 14.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 RLN68077.1 - 0.036 14.5 0.1 0.049 14.1 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_3 PF13192.6 RLN68077.1 - 0.066 13.3 0.1 0.11 12.6 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin domain DUF3450 PF11932.8 RLN68078.1 - 0.02 14.2 2.3 0.047 13.0 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Zwint PF15556.6 RLN68078.1 - 0.06 12.8 2.3 0.15 11.5 2.3 1.6 1 0 0 1 1 1 0 ZW10 interactor EF-hand_8 PF13833.6 RLN68078.1 - 0.091 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair APG6_N PF17675.1 RLN68078.1 - 0.1 13.2 8.6 0.027 15.0 2.9 2.6 3 0 0 3 3 3 0 Apg6 coiled-coil region DUF4200 PF13863.6 RLN68078.1 - 0.22 11.9 3.8 0.5 10.8 2.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF2205 PF10224.9 RLN68078.1 - 0.36 10.9 2.0 2 8.5 0.8 2.5 2 0 0 2 2 2 0 Short coiled-coil protein GIT_CC PF16559.5 RLN68078.1 - 0.39 10.6 2.0 2.2 8.2 2.0 2.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor MAP65_ASE1 PF03999.12 RLN68078.1 - 5.1 5.7 6.5 1.2 7.8 1.6 2.1 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) TBCA PF02970.16 RLN68078.1 - 5.9 7.3 5.8 5.8 7.3 3.0 2.4 2 1 0 2 2 2 0 Tubulin binding cofactor A Phage_CP76 PF06892.11 RLN68134.1 - 0.06 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) BT1 PF03092.16 RLN68138.1 - 5.5e-17 61.2 17.5 4.2e-13 48.4 1.1 3.2 3 0 0 3 3 3 3 BT1 family PUCC PF03209.15 RLN68138.1 - 0.00051 19.2 0.2 0.00051 19.2 0.2 2.8 3 1 0 3 3 3 1 PUCC protein BT1 PF03092.16 RLN68139.1 - 3.2e-15 55.4 13.0 3.9e-11 41.9 0.6 3.2 3 0 0 3 3 3 3 BT1 family SmpA_OmlA PF04355.13 RLN68139.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 SmpA / OmlA family tRNA_anti-codon PF01336.25 RLN68140.1 - 3.9e-08 33.2 0.0 6.5e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 RLN68140.1 - 0.036 13.9 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 BT1 PF03092.16 RLN68141.1 - 3.6e-19 68.4 6.3 2.1e-17 62.5 1.0 2.2 2 0 0 2 2 2 2 BT1 family BT1 PF03092.16 RLN68142.1 - 2.8e-18 65.4 14.0 1.7e-13 49.6 1.2 3.4 3 0 0 3 3 3 3 BT1 family MFS_1 PF07690.16 RLN68142.1 - 8.1e-07 28.3 35.6 8.1e-07 28.3 35.6 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Yip1 PF04893.17 RLN68142.1 - 0.02 14.6 0.8 0.02 14.6 0.8 4.9 2 1 2 4 4 4 0 Yip1 domain DUF5353 PF17304.2 RLN68142.1 - 2.3 8.0 7.7 0.27 11.0 2.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5353) Mre11_DNA_bind PF04152.14 RLN68143.1 - 2.1e-36 125.8 1.4 2.1e-36 125.8 1.4 2.7 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 RLN68143.1 - 1.6e-07 32.0 0.1 3.2e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3246 PF11596.8 RLN68143.1 - 8.1 5.8 13.0 0.25 10.8 0.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3246) TMEM154 PF15102.6 RLN68145.1 - 0.0055 16.6 0.7 0.0055 16.6 0.7 2.1 2 1 0 2 2 2 1 TMEM154 protein family Glycophorin_A PF01102.18 RLN68145.1 - 0.024 14.9 2.3 0.06 13.6 1.4 2.1 1 1 0 1 1 1 0 Glycophorin A Amnionless PF14828.6 RLN68145.1 - 0.06 12.2 0.1 0.06 12.2 0.1 1.5 1 1 0 2 2 2 0 Amnionless DUF2615 PF11027.8 RLN68145.1 - 0.26 11.4 1.8 0.34 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Trp_oprn_chp PF09534.10 RLN68146.1 - 0.44 10.3 5.2 0.095 12.5 0.5 2.2 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) E1-E2_ATPase PF00122.20 RLN68148.1 - 0.00049 19.7 0.1 0.022 14.3 0.0 2.3 2 0 0 2 2 2 2 E1-E2 ATPase TMEM51 PF15345.6 RLN68148.1 - 0.05 13.4 2.3 0.062 13.1 0.5 2.1 2 1 0 2 2 2 0 Transmembrane protein 51 HMGL-like PF00682.19 RLN68151.1 - 4.7e-91 305.0 0.0 5.7e-91 304.7 0.0 1.1 1 0 0 1 1 1 1 HMGL-like Glyco_hydro_3 PF00933.21 RLN68217.1 - 4.2e-45 154.5 0.0 5.7e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN68217.1 - 6.1e-29 101.4 0.0 1.1e-28 100.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fer2 PF00111.27 RLN68218.1 - 7.3e-13 48.3 1.5 9.4e-13 47.9 1.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain MCR PF18509.1 RLN68218.1 - 0.052 13.1 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 Magnetochrome domain Myb_DNA-bind_4 PF13837.6 RLN68219.1 - 0.025 14.9 0.1 1.6 9.2 0.0 2.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Lectin_N PF03954.14 RLN68219.1 - 0.081 12.7 0.2 0.22 11.3 0.2 1.7 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain FAD-SLDH PF12318.8 RLN68219.1 - 0.29 11.2 1.2 0.93 9.5 0.2 2.2 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase L27_1 PF09058.10 RLN68219.1 - 0.32 11.0 3.2 0.38 10.8 0.4 2.3 2 0 0 2 2 2 0 L27_1 Glyco_hydro_53 PF07745.13 RLN68220.1 - 2.6e-74 250.2 0.1 3.4e-74 249.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Glyco_hydro_53 PF07745.13 RLN68221.1 - 1.5e-72 244.5 0.1 1.9e-72 244.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Cellulase PF00150.18 RLN68221.1 - 0.078 12.4 0.0 0.34 10.3 0.0 1.9 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Methyltransf_25 PF13649.6 RLN68222.1 - 2.3e-12 47.4 0.1 6.6e-12 46.0 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN68222.1 - 7.1e-11 42.6 0.1 2e-10 41.2 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN68222.1 - 5.7e-08 32.8 0.0 1.1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN68222.1 - 9.6e-08 32.7 0.0 2.2e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN68222.1 - 3.7e-06 26.4 0.0 5.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 RLN68222.1 - 3.1e-05 23.8 0.0 7.6e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CD99L2 PF12301.8 RLN68222.1 - 0.072 13.4 2.2 0.18 12.1 2.2 1.6 1 0 0 1 1 1 0 CD99 antigen like protein 2 MTS PF05175.14 RLN68222.1 - 0.14 11.7 0.1 0.28 10.7 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain FYVE PF01363.21 RLN68223.1 - 4.4e-11 42.8 13.3 1.1e-10 41.5 13.3 1.7 1 0 0 1 1 1 1 FYVE zinc finger Ras PF00071.22 RLN68224.1 - 1.9e-28 99.1 0.0 1.2e-15 57.5 0.0 2.4 1 1 1 2 2 2 2 Ras family KHA PF11834.8 RLN68224.1 - 5e-13 48.9 0.0 1.2e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel SAP PF02037.27 RLN68224.1 - 7.2e-11 41.6 2.6 7.2e-11 41.6 2.6 2.6 3 0 0 3 3 3 1 SAP domain INCENP_ARK-bind PF03941.15 RLN68224.1 - 5.5e-10 39.0 2.9 6.5e-10 38.8 0.3 2.5 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Roc PF08477.13 RLN68224.1 - 1.3e-06 28.6 0.0 1.1e-05 25.6 0.0 2.7 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 RLN68224.1 - 0.56 10.7 12.5 0.52 10.8 6.8 3.2 2 0 0 2 2 2 0 AAA domain NAM-associated PF14303.6 RLN68224.1 - 0.87 10.3 0.0 0.87 10.3 0.0 7.9 3 3 2 5 5 5 0 No apical meristem-associated C-terminal domain VPS9 PF02204.18 RLN68225.1 - 6.6e-10 39.1 0.1 2.2e-09 37.4 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Oxysterol_BP PF01237.18 RLN68225.1 - 0.0022 16.9 0.0 0.0038 16.1 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein LIM_bind PF01803.16 RLN68225.1 - 0.035 13.6 0.3 0.076 12.5 0.3 1.5 1 0 0 1 1 1 0 LIM-domain binding protein Transthyretin PF00576.21 RLN68226.1 - 4.7e-37 127.0 0.1 5.3e-37 126.9 0.1 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family SpoIIIAH PF12685.7 RLN68227.1 - 0.12 12.2 2.8 0.16 11.8 1.8 1.7 1 1 1 2 2 2 0 SpoIIIAH-like protein Mito_fiss_reg PF05308.11 RLN68228.1 - 1.1 9.3 12.7 0.56 10.3 9.8 1.9 1 1 1 2 2 2 0 Mitochondrial fission regulator CENP-H PF05837.12 RLN68228.1 - 1.5 9.3 7.3 3.9 7.9 7.3 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF3482 PF11981.8 RLN68228.1 - 2.4 7.5 8.0 6.1 6.2 8.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) DUF966 PF06136.13 RLN68228.1 - 2.6 7.7 7.6 8.3 6.0 7.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF966) SpoIIIAH PF12685.7 RLN68228.1 - 6.6 6.5 7.9 2.2e+02 1.5 7.9 2.2 1 1 0 1 1 1 0 SpoIIIAH-like protein Myb_DNA-bind_4 PF13837.6 RLN68229.1 - 0.55 10.6 3.3 1 9.8 0.1 2.7 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain HrpB2 PF09487.10 RLN68230.1 - 0.11 12.9 0.7 0.21 12.0 0.2 1.7 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) COPI_assoc PF08507.10 RLN68232.1 - 5.1e-16 58.9 8.4 6.1e-16 58.7 8.4 1.1 1 0 0 1 1 1 1 COPI associated protein SLATT_6 PF18169.1 RLN68232.1 - 1.2 8.7 3.6 2 8.0 3.6 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 Seipin PF06775.14 RLN68233.1 - 0.00019 21.6 2.1 0.23 11.5 0.1 3.5 3 0 0 3 3 3 2 Putative adipose-regulatory protein (Seipin) CholecysA-Rec_N PF09193.10 RLN68233.1 - 0.016 15.2 1.3 16 5.6 0.2 3.6 3 0 0 3 3 3 0 Cholecystokinin A receptor, N-terminal Spermine_synt_N PF17284.2 RLN68233.1 - 0.091 12.7 0.0 36 4.3 0.0 3.2 3 0 0 3 3 3 0 Spermidine synthase tetramerisation domain TRAP-gamma PF07074.12 RLN68233.1 - 1.2 8.7 11.2 5.5 6.5 0.5 3.9 3 0 0 3 3 3 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF1084 PF06454.11 RLN68234.1 - 5.7e-08 32.5 16.2 0.00047 19.6 4.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1084) CholecysA-Rec_N PF09193.10 RLN68234.1 - 0.063 13.3 0.4 19 5.3 0.0 3.0 2 0 0 2 2 2 0 Cholecystokinin A receptor, N-terminal Trp_oprn_chp PF09534.10 RLN68234.1 - 0.14 11.9 1.6 25 4.6 0.0 3.5 4 0 0 4 4 4 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Antistasin PF02822.14 RLN68234.1 - 0.37 11.5 3.4 19 6.0 0.0 3.6 3 0 0 3 3 3 0 Antistasin family LapA_dom PF06305.11 RLN68234.1 - 8.5 6.3 6.6 1.7 8.6 0.1 2.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain p450 PF00067.22 RLN68235.1 - 3.8e-67 227.0 0.0 4.8e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 RLN68236.1 - 2.9e-11 42.8 0.2 3.1e-11 42.7 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Chorismate_bind PF00425.18 RLN68237.1 - 4e-96 321.5 0.0 6.4e-96 320.9 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 RLN68237.1 - 2.9e-28 98.9 0.0 4.5e-27 95.0 0.0 2.7 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region DctA-YdbH PF11739.8 RLN68237.1 - 0.2 11.3 0.0 0.38 10.4 0.0 1.3 1 0 0 1 1 1 0 Dicarboxylate transport ArfGap PF01412.18 RLN68238.1 - 5e-32 110.4 0.2 5e-32 110.4 0.2 3.3 3 1 0 3 3 3 1 Putative GTPase activating protein for Arf Armet PF10208.9 RLN68238.1 - 7.2e-14 51.9 7.2 3.7e-13 49.6 7.1 2.2 1 1 0 1 1 1 1 Degradation arginine-rich protein for mis-folding SAP PF02037.27 RLN68238.1 - 0.001 18.8 0.0 0.0027 17.4 0.0 1.8 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 RLN68238.1 - 0.0019 17.9 0.0 0.0048 16.6 0.0 1.7 1 0 0 1 1 1 1 HeH/LEM domain DUF2250 PF10007.9 RLN68238.1 - 0.022 14.8 0.3 0.087 12.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) tRNA_lig_CPD PF08302.11 RLN68238.1 - 0.038 13.4 0.4 0.078 12.4 0.4 1.5 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain NAD_binding_5 PF07994.12 RLN68240.1 - 1.7e-74 251.1 0.0 2e-74 250.9 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 RLN68240.1 - 2.5e-48 162.8 0.4 3.7e-48 162.3 0.4 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase IQ PF00612.27 RLN68243.1 - 7.4e-05 22.2 4.4 0.024 14.4 0.4 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif Atg14 PF10186.9 RLN68243.1 - 0.045 12.8 0.2 0.087 11.9 0.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NADHdh_A3 PF14987.6 RLN68244.1 - 0.00067 19.9 0.0 0.00093 19.4 0.0 1.3 1 0 0 1 1 1 1 NADH dehydrogenase 1 alpha subcomplex subunit 3 Pepdidase_M14_N PF18027.1 RLN68347.1 - 0.0088 16.4 0.1 0.016 15.5 0.1 1.4 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Spc42p PF11544.8 RLN68347.1 - 1.8 8.6 4.8 14 5.7 0.6 2.5 1 1 1 2 2 2 0 Spindle pole body component Spc42p Hyr1 PF15789.5 RLN68355.1 - 2.7 7.6 5.4 17 5.1 1.2 2.5 2 0 0 2 2 2 0 Hyphally regulated cell wall GPI-anchored protein 1 PIF1 PF05970.14 RLN68356.1 - 9.3e-45 153.4 0.0 2.4e-43 148.7 0.0 2.4 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 RLN68356.1 - 8.7e-21 74.5 0.0 1.7e-20 73.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RLN68356.1 - 1.4e-07 32.0 0.0 2.9e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RLN68356.1 - 5.6e-05 23.4 0.4 0.00026 21.3 0.4 2.0 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 RLN68356.1 - 9.6e-05 22.1 0.0 0.00023 20.9 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 RLN68356.1 - 0.00035 21.0 0.3 0.0011 19.4 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain Herpes_Helicase PF02689.14 RLN68356.1 - 0.0016 16.4 0.1 0.047 11.6 0.0 2.1 2 0 0 2 2 2 1 Helicase PhoH PF02562.16 RLN68356.1 - 0.0027 17.2 0.1 0.007 15.8 0.0 1.6 2 0 0 2 2 2 1 PhoH-like protein AAA_25 PF13481.6 RLN68356.1 - 0.0027 17.3 0.2 0.03 13.9 0.0 2.2 1 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RLN68356.1 - 0.0092 15.5 0.1 0.017 14.6 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 RLN68356.1 - 0.012 15.6 0.3 0.17 11.9 0.3 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 RLN68356.1 - 0.018 14.8 0.1 0.7 9.6 0.1 2.9 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 RLN68356.1 - 0.027 14.4 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase DEAD PF00270.29 RLN68356.1 - 0.047 13.5 0.0 8.4 6.1 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF815 PF05673.13 RLN68356.1 - 0.07 12.3 0.1 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 RLN68356.1 - 0.11 12.3 0.2 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein T2SSE PF00437.20 RLN68356.1 - 0.14 11.2 0.1 0.25 10.3 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 RLN68356.1 - 0.19 11.7 0.0 0.45 10.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain ADH_N PF08240.12 RLN68357.1 - 1.6e-25 89.1 2.7 2.7e-25 88.4 2.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN68357.1 - 2.4e-20 72.8 0.6 3.7e-20 72.2 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN68357.1 - 9.4e-05 23.5 0.0 0.00017 22.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN68357.1 - 0.00011 21.6 0.3 0.00047 19.6 0.1 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN68357.1 - 0.00026 20.4 0.8 0.00042 19.7 0.8 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 RLN68357.1 - 0.018 15.9 0.2 0.04 14.7 0.1 1.6 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_10 PF13460.6 RLN68357.1 - 0.018 14.9 0.1 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Shikimate_DH PF01488.20 RLN68357.1 - 0.021 14.9 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Oxidored_nitro PF00148.19 RLN68357.1 - 0.081 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase PPR_2 PF13041.6 RLN68358.1 - 1.6e-16 60.2 4.2 7.1e-08 32.5 0.0 5.1 1 1 4 5 5 5 3 PPR repeat family PPR_3 PF13812.6 RLN68358.1 - 8.2e-16 57.8 0.0 2.1e-07 30.9 0.0 3.3 1 1 2 3 3 3 3 Pentatricopeptide repeat domain PPR_long PF17177.4 RLN68358.1 - 4e-14 52.5 1.4 2.2e-07 30.5 0.1 2.4 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 RLN68358.1 - 5.8e-10 38.7 1.0 0.0035 17.5 0.0 4.9 5 0 0 5 5 5 2 PPR repeat PPR_1 PF12854.7 RLN68358.1 - 0.00033 20.3 0.2 0.19 11.4 0.0 3.6 4 0 0 4 4 4 1 PPR repeat MNE1 PF13762.6 RLN68358.1 - 0.015 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial splicing apparatus component Cas_Cmr5 PF09701.10 RLN68358.1 - 0.064 13.6 0.6 0.14 12.5 0.1 1.7 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cmr5) UPF0004 PF00919.20 RLN68358.1 - 0.079 13.0 0.2 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 PPR_2 PF13041.6 RLN68359.1 - 2.4e-22 78.9 3.6 0.0041 17.3 0.0 8.7 4 2 5 9 9 9 6 PPR repeat family PPR_3 PF13812.6 RLN68359.1 - 7.4e-20 70.8 7.1 0.00013 21.9 0.2 7.2 3 2 5 8 8 8 7 Pentatricopeptide repeat domain PPR_long PF17177.4 RLN68359.1 - 9.5e-14 51.3 6.2 4.1e-05 23.1 0.2 4.5 1 1 4 5 5 5 4 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 RLN68359.1 - 2.8e-13 49.1 0.1 1.3 9.4 0.0 9.0 9 0 0 9 9 9 2 PPR repeat PPR_1 PF12854.7 RLN68359.1 - 0.019 14.7 2.3 18 5.1 0.0 4.5 5 0 0 5 5 5 0 PPR repeat TPR_19 PF14559.6 RLN68359.1 - 0.033 14.7 4.5 4.5 7.9 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_Prp PF04327.12 RLN68359.1 - 0.13 12.5 0.1 27 5.1 0.0 2.8 2 0 0 2 2 2 0 Cysteine protease Prp COX5A PF02284.16 RLN68359.1 - 0.16 11.9 0.8 1.9 8.6 0.0 3.0 3 0 0 3 3 3 0 Cytochrome c oxidase subunit Va PPR_long PF17177.4 RLN68360.1 - 4.3e-14 52.4 8.0 3e-07 30.0 0.3 3.6 1 1 2 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 RLN68360.1 - 9e-14 51.4 7.3 0.16 12.2 0.0 8.5 5 2 5 10 10 10 4 PPR repeat family PPR_3 PF13812.6 RLN68360.1 - 7.3e-13 48.4 9.1 0.0049 16.9 0.1 7.9 4 3 5 9 9 9 5 Pentatricopeptide repeat domain PPR PF01535.20 RLN68360.1 - 9.9e-08 31.7 5.0 15 6.1 0.0 8.3 10 0 0 10 10 10 2 PPR repeat Utp13 PF08625.11 RLN68360.1 - 0.02 14.8 4.8 2.6 7.9 0.3 2.9 3 0 0 3 3 3 0 Utp13 specific WD40 associated domain TPR_14 PF13428.6 RLN68360.1 - 0.048 14.5 3.8 4.1 8.5 0.0 5.2 3 2 3 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN68360.1 - 0.049 14.1 3.4 1.6 9.3 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Dynamin_N PF00350.23 RLN68361.1 - 0.0029 17.7 1.3 0.0029 17.7 1.3 1.5 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 RLN68361.1 - 0.012 15.7 0.3 0.036 14.1 0.1 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 RLN68361.1 - 0.022 14.5 0.6 0.03 14.0 0.1 1.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 RLN68361.1 - 0.072 12.1 0.3 0.77 8.8 0.1 1.9 1 1 1 2 2 2 0 Type II/IV secretion system protein TPR_2 PF07719.17 RLN68363.1 - 9.4e-16 56.6 1.5 0.00014 21.7 0.6 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN68363.1 - 3.2e-14 52.1 3.2 0.0012 18.6 1.4 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN68363.1 - 2.1e-10 39.9 6.1 0.0061 16.7 0.0 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN68363.1 - 3.6e-10 39.4 2.7 0.00096 18.8 1.6 3.4 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 RLN68363.1 - 7.3e-09 36.1 0.5 0.0018 18.8 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat FKBP_C PF00254.28 RLN68363.1 - 1.4e-08 35.0 0.0 2.6e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_19 PF14559.6 RLN68363.1 - 6.9e-08 32.9 3.3 0.0075 16.7 0.0 2.7 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN68363.1 - 2.4e-07 31.0 0.4 0.024 15.4 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN68363.1 - 7.5e-07 29.4 2.2 0.0051 17.1 0.1 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN68363.1 - 3.9e-05 23.6 7.8 0.043 13.9 0.3 3.5 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 RLN68363.1 - 0.00014 21.6 0.8 0.16 12.0 0.3 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN68363.1 - 0.00045 20.0 4.6 0.54 10.2 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN68363.1 - 0.00074 19.7 1.1 1.9 9.0 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN68363.1 - 0.0076 16.4 2.4 1.2 9.5 0.0 2.6 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 RLN68363.1 - 0.012 15.7 0.6 0.012 15.7 0.6 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 RLN68363.1 - 0.025 15.2 4.0 6.6 7.6 0.1 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 RLN68363.1 - 0.026 14.7 0.1 0.25 11.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Death PF00531.22 RLN68363.1 - 0.09 13.0 1.1 0.81 9.9 0.2 2.3 2 0 0 2 2 2 0 Death domain SHNi-TPR PF10516.9 RLN68363.1 - 0.093 12.2 1.8 0.21 11.1 0.2 2.3 2 0 0 2 2 2 0 SHNi-TPR DUF2225 PF09986.9 RLN68363.1 - 0.26 11.0 4.5 0.45 10.2 4.4 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Alkyl_sulf_dimr PF14863.6 RLN68363.1 - 1.6 9.2 5.7 7.1 7.1 0.3 2.5 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation ADH_N PF08240.12 RLN68364.1 - 6.4e-26 90.4 2.4 6.4e-26 90.4 2.4 1.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN68364.1 - 2.7e-21 75.9 0.2 4.6e-21 75.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN68364.1 - 3.6e-07 31.3 0.0 6e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 RLN68364.1 - 4.9e-05 22.7 0.1 7.6e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 RLN68364.1 - 0.00013 21.3 0.1 0.00025 20.5 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PDZ_6 PF17820.1 RLN68364.1 - 0.058 13.2 0.0 13 5.7 0.0 2.5 2 0 0 2 2 2 0 PDZ domain GFO_IDH_MocA PF01408.22 RLN68364.1 - 0.13 13.1 0.1 0.52 11.1 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 RLN68364.1 - 0.16 12.0 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DMRL_synthase PF00885.19 RLN68365.1 - 4.6e-10 39.5 0.2 6e-10 39.1 0.2 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DMRL_synthase PF00885.19 RLN68366.1 - 1.2e-14 54.3 0.0 1.6e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DUF2374 PF09574.10 RLN68366.1 - 0.21 11.4 4.1 1.3 8.9 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (Duf2374) Caldesmon PF02029.15 RLN68367.1 - 0.015 14.1 10.2 0.017 13.9 10.2 1.0 1 0 0 1 1 1 0 Caldesmon Beta-prism_lec PF16458.5 RLN68367.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Beta-prism lectin YdfA_immunity PF12127.8 RLN68367.1 - 0.15 11.1 1.2 0.18 10.8 1.2 1.2 1 0 0 1 1 1 0 SigmaW regulon antibacterial MotA_ExbB PF01618.16 RLN68367.1 - 0.2 11.4 1.3 0.65 9.7 0.0 2.3 2 1 0 2 2 2 0 MotA/TolQ/ExbB proton channel family Zip PF02535.22 RLN68369.1 - 1.1e-11 44.6 11.3 1.1e-10 41.3 11.3 2.5 1 1 0 1 1 1 1 ZIP Zinc transporter CbtB PF09489.10 RLN68369.1 - 0.059 13.5 0.5 0.059 13.5 0.5 3.0 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) Thioredoxin_10 PF17991.1 RLN68371.1 - 0.02 15.4 0.2 0.059 13.9 0.1 1.7 1 1 0 2 2 2 0 Thioredoxin like C-terminal domain MKT1_N PF12247.8 RLN68372.1 - 0.17 12.3 0.0 0.99 9.8 0.0 2.0 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication HR1 PF02185.16 RLN68373.1 - 0.026 14.6 3.5 0.032 14.3 3.5 1.4 1 1 0 1 1 1 0 Hr1 repeat AFG1_ATPase PF03969.16 RLN68374.1 - 5.8e-96 321.5 0.0 7.4e-96 321.2 0.0 1.1 1 0 0 1 1 1 1 AFG1-like ATPase AAA_16 PF13191.6 RLN68374.1 - 0.0027 18.1 0.5 0.25 11.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 RLN68374.1 - 0.0086 16.1 0.0 0.029 14.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RLN68374.1 - 0.059 13.7 0.1 6.1 7.2 0.1 2.3 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 RLN68374.1 - 0.062 13.1 0.0 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_22 PF13401.6 RLN68374.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Phage_holin_5_1 PF06946.11 RLN68375.1 - 0.026 14.9 0.1 0.053 13.9 0.0 1.5 1 1 0 1 1 1 0 Bacteriophage A118-like holin, Hol118 Vac14_Fab1_bd PF12755.7 RLN68376.1 - 9.2e-50 167.2 1.0 1.6e-42 144.0 0.0 4.5 2 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region Vac14_Fig4_bd PF11916.8 RLN68376.1 - 1.9e-45 154.7 9.8 7e-25 87.7 1.8 3.3 2 1 1 3 3 3 2 Vacuolar protein 14 C-terminal Fig4p binding HEAT PF02985.22 RLN68376.1 - 1.2e-14 53.1 5.2 8e-05 22.6 0.0 7.3 7 0 0 7 7 7 3 HEAT repeat Cnd1 PF12717.7 RLN68376.1 - 4e-09 36.7 6.5 0.0028 17.7 0.1 5.1 3 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 RLN68376.1 - 8.5e-09 35.7 1.5 0.065 13.8 0.0 5.5 5 0 0 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 RLN68376.1 - 2.2e-07 31.1 2.1 1.3 9.5 0.0 5.6 4 1 0 4 4 4 2 HEAT repeats CLASP_N PF12348.8 RLN68376.1 - 3.3e-07 30.1 0.4 0.001 18.7 0.0 4.0 3 2 2 5 5 5 1 CLASP N terminal MMS19_C PF12460.8 RLN68376.1 - 0.00062 19.0 0.7 0.78 8.8 2.4 3.0 3 2 1 4 4 4 2 RNAPII transcription regulator C-terminal Tti2 PF10521.9 RLN68376.1 - 0.0012 18.5 0.1 0.26 10.8 0.0 3.1 3 0 0 3 3 3 1 Tti2 family RTP1_C1 PF10363.9 RLN68376.1 - 0.0042 17.2 4.5 0.043 14.0 0.4 3.7 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 ParcG PF10274.9 RLN68376.1 - 0.0082 16.3 1.1 0.065 13.3 0.4 2.6 1 1 3 4 4 4 2 Parkin co-regulated protein Arm PF00514.23 RLN68376.1 - 0.05 13.7 0.9 17 5.7 0.0 4.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 RLN68376.1 - 0.071 12.9 0.2 0.25 11.1 0.2 1.9 1 1 1 2 2 2 0 rRNA processing/ribosome biogenesis RasGEF_N_2 PF14663.6 RLN68376.1 - 0.83 10.1 7.7 9.3 6.7 0.0 4.0 4 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain WD40 PF00400.32 RLN68377.1 - 2.6e-11 43.9 2.7 0.047 14.6 0.0 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF1479 PF07350.12 RLN68378.1 - 2.6e-05 23.2 0.0 0.018 13.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.13 RLN68378.1 - 4.8e-05 23.7 0.0 0.00021 21.6 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) tRNA_Me_trans PF03054.16 RLN68379.1 - 1.3e-113 379.4 0.0 3.9e-107 358.1 0.0 2.0 2 0 0 2 2 2 2 tRNA methyl transferase NAD_synthase PF02540.17 RLN68379.1 - 1.2e-06 27.8 0.0 3.9e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 NAD synthase ThiI PF02568.14 RLN68379.1 - 2.3e-05 24.1 0.0 0.0002 21.0 0.0 2.2 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 RLN68379.1 - 0.00047 19.7 0.1 0.0018 17.8 0.1 2.0 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 RLN68379.1 - 0.0085 15.9 0.2 0.08 12.7 0.2 2.3 1 1 0 1 1 1 1 PP-loop family SF-assemblin PF06705.11 RLN68380.1 - 4e-08 32.9 13.2 2e-05 24.0 6.5 2.1 2 0 0 2 2 2 2 SF-assemblin/beta giardin UBN_AB PF14075.6 RLN68380.1 - 0.25 11.0 4.5 0.4 10.4 4.5 1.5 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Exonuc_VII_L PF02601.15 RLN68380.1 - 3.5 7.1 13.4 58 3.1 13.4 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit Ribosomal_L37e PF01907.19 RLN68381.1 - 1.4e-28 98.8 10.5 2.5e-28 98.0 10.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 RLN68381.1 - 0.017 15.1 1.1 0.026 14.5 1.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_10 PF16685.5 RLN68381.1 - 0.036 14.2 1.8 0.049 13.8 1.8 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 NRDD PF13597.6 RLN68381.1 - 0.04 12.7 0.9 0.048 12.4 0.9 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase HypA PF01155.19 RLN68381.1 - 0.065 13.3 0.7 0.087 12.9 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C4pol PF14260.6 RLN68381.1 - 0.083 13.4 3.3 0.16 12.4 2.7 1.8 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DUF35_N PF12172.8 RLN68381.1 - 0.18 11.7 2.8 0.33 10.9 2.8 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF1258 PF06869.12 RLN68381.1 - 0.81 9.1 4.5 0.44 10.0 2.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) DUF2688 PF10892.8 RLN68381.1 - 0.83 9.2 5.8 1.9 8.0 3.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) Ribosomal_S14 PF00253.21 RLN68381.1 - 1 9.2 10.2 0.35 10.7 0.4 2.6 1 1 2 3 3 3 0 Ribosomal protein S14p/S29e Ribonucleas_3_3 PF14622.6 RLN68382.1 - 1.2e-17 64.3 0.0 2.1e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 RLN68382.1 - 4.7e-17 62.5 0.0 8.5e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain CDC45 PF02724.14 RLN68383.1 - 0.00026 19.4 21.5 0.00029 19.3 21.5 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 RLN68383.1 - 0.0026 16.1 26.8 0.0029 15.9 26.8 1.1 1 0 0 1 1 1 1 Nop14-like family DUF2457 PF10446.9 RLN68383.1 - 0.0065 15.7 28.4 0.0089 15.2 28.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Apt1 PF10351.9 RLN68383.1 - 0.034 13.0 9.3 0.038 12.8 9.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SDA1 PF05285.12 RLN68383.1 - 0.04 13.3 31.6 0.044 13.2 31.6 1.2 1 0 0 1 1 1 0 SDA1 Sporozoite_P67 PF05642.11 RLN68383.1 - 0.12 10.4 11.5 0.15 10.1 11.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Zip PF02535.22 RLN68383.1 - 0.25 10.5 5.1 0.26 10.5 5.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIF_alpha PF05793.12 RLN68383.1 - 0.29 9.7 38.3 0.44 9.1 38.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CNDH2_C PF16858.5 RLN68383.1 - 0.35 10.7 14.4 0.41 10.5 14.4 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Merozoite_SPAM PF07133.11 RLN68383.1 - 0.35 10.8 35.8 0.53 10.3 35.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Mpp10 PF04006.12 RLN68383.1 - 0.64 8.4 33.5 0.86 8.0 33.5 1.1 1 0 0 1 1 1 0 Mpp10 protein Tim54 PF11711.8 RLN68383.1 - 1.4 7.6 10.7 1.8 7.2 10.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF913 PF06025.12 RLN68383.1 - 2.9 6.8 11.1 3.6 6.5 11.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 RLN68383.1 - 3 6.5 12.1 3.2 6.4 12.1 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 RLN68383.1 - 3.7 6.2 16.1 4.4 6.0 16.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Sec62 PF03839.16 RLN68383.1 - 3.9 6.9 9.5 5.6 6.4 9.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DNA_pol_phi PF04931.13 RLN68383.1 - 4.2 5.3 44.2 6.1 4.8 44.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Spore_coat_CotO PF14153.6 RLN68383.1 - 5 7.0 14.4 6.4 6.7 14.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF1980 PF09323.10 RLN68383.1 - 5.1 7.0 5.4 7.5 6.4 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF2151 PF10221.9 RLN68383.1 - 7.4 5.0 11.1 7.9 4.9 11.1 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator CDC27 PF09507.10 RLN68383.1 - 7.7 5.8 38.6 3.5 6.9 36.5 1.4 1 1 1 2 2 2 0 DNA polymerase subunit Cdc27 SpoIIP PF07454.11 RLN68383.1 - 7.7 5.9 13.1 10 5.5 13.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FAM60A PF15396.6 RLN68383.1 - 8.6 6.3 11.1 12 5.9 11.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DEAD PF00270.29 RLN68402.1 - 3.8e-06 26.8 0.4 0.014 15.2 0.1 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN68402.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.8 1 1 0 1 1 1 0 Helicase conserved C-terminal domain CBS PF00571.28 RLN68402.1 - 0.057 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 CBS domain Kinesin PF00225.23 RLN68410.1 - 4.2e-91 305.3 0.2 8.4e-91 304.3 0.2 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN68410.1 - 3.2e-19 69.3 0.0 8e-14 51.8 0.0 2.5 1 1 1 2 2 2 2 Microtubule binding Guanylate_cyc PF00211.20 RLN68411.1 - 5.8e-08 32.6 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Actin PF00022.19 RLN68582.1 - 4.4e-125 417.5 0.0 1.6e-124 415.6 0.0 1.7 1 1 0 1 1 1 1 Actin DUF3453 PF11935.8 RLN68583.1 - 3.6e-10 39.9 0.1 6.8e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) GHMP_kinases_N PF00288.26 RLN68583.1 - 0.061 13.6 3.5 0.28 11.4 3.5 2.2 1 0 0 1 1 1 0 GHMP kinases N terminal domain MFS_1 PF07690.16 RLN68584.1 - 2.6e-34 118.7 27.9 2.6e-34 118.7 27.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 RLN68584.1 - 1.7e-26 92.7 19.4 2e-20 72.6 0.7 3.2 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 RLN68584.1 - 1e-18 67.5 22.6 2e-18 66.5 22.4 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2530 PF10745.9 RLN68584.1 - 2.3 8.5 12.9 0.38 11.0 1.4 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) PUCC PF03209.15 RLN68584.1 - 9.3 5.1 18.1 0.44 9.5 5.9 2.4 2 0 0 2 2 2 0 PUCC protein CENP-F_leu_zip PF10473.9 RLN68608.1 - 0.028 14.5 18.3 0.41 10.7 0.1 3.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 RLN68608.1 - 0.19 11.0 21.2 1 8.6 5.9 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF4472 PF14739.6 RLN68608.1 - 0.28 11.9 0.2 0.28 11.9 0.2 4.2 3 1 2 5 5 5 0 Domain of unknown function (DUF4472) YabA PF06156.13 RLN68608.1 - 0.83 10.3 9.4 1.3 9.7 0.4 3.5 2 1 0 3 3 3 0 Initiation control protein YabA PPP4R2 PF09184.11 RLN68608.1 - 3.1 7.3 7.1 5.5 6.5 7.1 1.4 1 0 0 1 1 1 0 PPP4R2 SOBP PF15279.6 RLN68674.1 - 0.063 13.9 8.5 0.09 13.4 8.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein RRM_1 PF00076.22 RLN68674.1 - 0.087 12.7 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apt1 PF10351.9 RLN68674.1 - 0.78 8.5 14.9 1.1 8.1 14.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4614 PF15391.6 RLN68674.1 - 9.3 6.2 22.5 2 8.4 17.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4614) Nucleo_P87 PF07267.11 RLN68674.1 - 9.9 4.9 7.2 13 4.4 7.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ank_4 PF13637.6 RLN68675.1 - 3.1e-11 43.6 0.0 8.8e-06 26.2 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN68675.1 - 4.7e-10 39.9 0.1 4.2e-08 33.7 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN68675.1 - 1.5e-09 37.9 0.0 3.2e-08 33.7 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN68675.1 - 1.5e-06 28.0 0.1 0.011 16.1 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 RLN68675.1 - 2.1e-06 27.9 0.5 0.022 15.2 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat zf-rbx1 PF12678.7 RLN68676.1 - 8.2e-11 42.0 11.2 8.2e-11 42.0 11.2 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 RLN68676.1 - 4.4e-09 36.5 12.2 4.4e-09 36.5 12.2 2.5 2 0 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 RLN68676.1 - 0.0001 22.3 4.9 0.0001 22.3 4.9 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 RLN68676.1 - 0.00017 21.3 17.4 0.00027 20.7 13.4 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN68676.1 - 0.00056 19.9 7.0 0.00063 19.7 3.9 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RLN68676.1 - 0.00073 19.4 11.6 0.00073 19.4 11.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN68676.1 - 0.0012 18.6 12.1 0.0039 16.9 6.8 3.5 2 1 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 RLN68676.1 - 0.0019 18.1 10.2 0.0019 18.1 10.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RLN68676.1 - 0.86 9.5 19.6 0.16 11.8 12.9 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 RLN68676.1 - 1.5 9.0 13.5 0.44 10.7 8.5 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 RLN68676.1 - 4.7 7.2 15.4 4.3 7.3 10.3 2.8 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Ribosomal_60s PF00428.19 RLN68677.1 - 3.9e-13 49.8 2.1 4.8e-13 49.5 2.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Herpes_glycop_D PF01537.17 RLN68679.1 - 0.0062 16.7 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Herpesvirus glycoprotein D/GG/GX domain Transglut_core PF01841.19 RLN68679.1 - 0.065 13.7 0.0 0.29 11.6 0.0 2.0 2 0 0 2 2 2 0 Transglutaminase-like superfamily AAA_6 PF12774.7 RLN68680.1 - 3e-157 522.7 0.0 1.6e-156 520.4 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN68680.1 - 2.2e-127 425.5 5.9 2.2e-127 425.5 5.9 3.2 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RLN68680.1 - 8.7e-103 343.2 0.0 2.7e-101 338.3 0.0 2.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 RLN68680.1 - 1.6e-93 313.3 0.7 9.2e-92 307.5 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 RLN68680.1 - 3.1e-93 310.9 0.4 3.1e-93 310.9 0.4 3.0 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 RLN68680.1 - 2.4e-77 258.5 0.1 6.2e-76 253.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RLN68680.1 - 2.2e-57 193.4 0.1 1.3e-56 190.9 0.0 2.4 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RLN68680.1 - 5.6e-45 152.3 0.0 2.9e-42 143.5 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 RLN68680.1 - 7e-43 147.0 5.9 7e-43 147.0 5.9 2.5 2 1 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 RLN68680.1 - 6.1e-33 113.7 0.6 2.6e-32 111.6 0.6 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RLN68680.1 - 2.1e-22 79.2 0.4 1.4e-19 70.1 0.2 2.9 2 0 0 2 2 2 1 AAA+ lid domain Cyclin_C PF02984.19 RLN68680.1 - 1.2e-14 54.4 0.0 3.9e-14 52.8 0.0 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain AAA_5 PF07728.14 RLN68680.1 - 4e-12 46.3 0.0 0.00025 21.1 0.0 5.9 5 1 0 5 5 4 1 AAA domain (dynein-related subfamily) Cyclin_N PF00134.23 RLN68680.1 - 1.1e-09 38.1 0.1 4.6e-09 36.1 0.1 2.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain AAA_30 PF13604.6 RLN68680.1 - 2.3e-08 34.0 0.1 2.7e-05 24.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RLN68680.1 - 8.9e-07 29.4 2.2 0.072 13.5 0.0 4.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 RLN68680.1 - 8.1e-05 21.8 0.0 0.00026 20.2 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein RNA_helicase PF00910.22 RLN68680.1 - 0.00066 20.0 0.0 1 9.7 0.0 3.3 2 0 0 2 2 2 1 RNA helicase DUF4349 PF14257.6 RLN68680.1 - 0.0025 17.3 0.5 0.0025 17.3 0.5 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4349) AAA_18 PF13238.6 RLN68680.1 - 0.0085 16.6 0.4 4.2 7.9 0.0 4.6 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.6 RLN68680.1 - 0.022 15.1 1.3 0.85 9.9 0.0 3.5 3 0 0 3 3 2 0 AAA domain ATPase_2 PF01637.18 RLN68680.1 - 0.03 14.3 0.1 0.19 11.6 0.0 2.6 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 RLN68680.1 - 0.033 14.6 2.8 12 6.2 0.0 4.7 5 0 0 5 5 3 0 AAA ATPase domain AAA_22 PF13401.6 RLN68680.1 - 0.034 14.4 0.1 2.9 8.2 0.0 3.3 2 0 0 2 2 2 0 AAA domain Plasmid_RAQPRD PF09686.10 RLN68680.1 - 0.049 13.8 3.0 1.8 8.8 0.0 4.6 3 1 1 4 4 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF87 PF01935.17 RLN68680.1 - 0.052 13.6 0.0 0.052 13.6 0.0 3.5 3 0 0 3 3 3 0 Helicase HerA, central domain DUF4423 PF14394.6 RLN68680.1 - 0.053 13.2 1.9 0.33 10.6 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) IstB_IS21 PF01695.17 RLN68680.1 - 0.065 13.0 0.0 0.38 10.5 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein E2F_CC-MB PF16421.5 RLN68680.1 - 0.066 13.6 0.6 0.31 11.4 0.6 2.2 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain DEAD PF00270.29 RLN68680.1 - 0.15 11.8 0.0 0.74 9.6 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase Roc PF08477.13 RLN68680.1 - 0.17 12.1 0.2 0.94 9.7 0.0 2.5 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase CK2S PF15011.6 RLN68680.1 - 0.51 10.2 6.8 0.23 11.3 0.6 3.2 2 0 0 2 2 2 0 Casein Kinase 2 substrate Snapin_Pallidin PF14712.6 RLN68680.1 - 1 9.8 10.2 4.2 7.9 2.4 3.6 2 0 0 2 2 2 0 Snapin/Pallidin DUF3740 PF12548.8 RLN68680.1 - 1.4 9.4 3.5 0.65 10.4 0.2 2.2 2 0 0 2 2 1 0 Sulfatase protein Baculo_PEP_C PF04513.12 RLN68680.1 - 1.7 8.7 13.6 1.5 8.9 1.1 4.9 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CCDC-167 PF15188.6 RLN68680.1 - 2.8 8.3 5.2 27 5.2 0.2 4.1 3 0 0 3 3 2 0 Coiled-coil domain-containing protein 167 PDZ PF00595.24 RLN68681.1 - 0.012 16.0 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 PDZ domain C2 PF00168.30 RLN68702.1 - 7.1e-07 29.5 0.0 2.5e-06 27.7 0.0 2.0 2 1 0 2 2 2 1 C2 domain SK_channel PF03530.14 RLN68703.1 - 7.1e-38 129.1 0.3 2.1e-37 127.6 0.3 1.8 1 0 0 1 1 1 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 RLN68703.1 - 1.1e-13 50.9 6.7 1.3e-12 47.5 4.5 2.7 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 RLN68703.1 - 0.0028 16.9 1.2 0.0058 15.9 1.2 1.6 1 1 0 1 1 1 1 Ion transport protein SlyX PF04102.12 RLN68703.1 - 0.21 12.2 2.2 4.9 7.8 0.0 2.9 2 1 1 3 3 3 0 SlyX MSA-2c PF12238.8 RLN68703.1 - 0.26 11.2 1.8 0.63 10.0 1.8 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF1282 PF06930.12 RLN68703.1 - 7 6.4 8.6 0.19 11.5 1.5 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1282) Peptidase_M16_M PF16187.5 RLN68704.1 - 1.5e-58 198.3 0.0 2.1e-58 197.9 0.0 1.2 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 RLN68704.1 - 2.3e-32 112.0 0.0 5e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 RLN68704.1 - 4e-24 85.6 0.0 9.3e-15 55.1 0.0 2.3 2 0 0 2 2 2 2 Peptidase M16 inactive domain Ribosomal_S8 PF00410.19 RLN68705.1 - 3.4e-13 49.7 0.1 5.6e-13 48.9 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 NGP1NT PF08153.12 RLN68706.1 - 1.5e-45 154.5 0.0 2.1e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 NGP1NT (NUC091) domain GAF PF01590.26 RLN68792.1 - 0.0005 20.7 1.3 0.0013 19.4 0.3 2.2 2 0 0 2 2 2 1 GAF domain FYVE PF01363.21 RLN68792.1 - 0.0047 17.0 8.8 0.016 15.3 8.8 2.0 1 1 0 1 1 1 1 FYVE zinc finger FYVE PF01363.21 RLN68793.1 - 3.1e-06 27.2 7.7 6.7e-06 26.1 7.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN68793.1 - 0.86 9.8 6.9 0.71 10.1 4.7 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger Glyco_hydro_31 PF01055.26 RLN68794.1 - 7.6e-05 22.1 0.0 9.9e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF2093 PF09866.9 RLN68794.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) ABC_tran PF00005.27 RLN68796.1 - 0.0038 17.7 0.1 0.006 17.1 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 RLN68796.1 - 0.044 13.5 0.1 0.084 12.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN68796.1 - 0.053 13.1 0.1 0.08 12.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 RLN68796.1 - 0.23 11.9 0.2 0.53 10.8 0.1 1.5 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 RLN68797.1 - 9.9e-30 103.5 27.4 9.9e-30 103.5 27.4 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RLN68797.1 - 3.6e-14 53.5 0.0 6.3e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter PDR_assoc PF08370.11 RLN68797.1 - 0.0044 16.7 1.1 0.0044 16.7 1.1 2.4 2 0 0 2 2 2 1 Plant PDR ABC transporter associated AAA_22 PF13401.6 RLN68797.1 - 0.065 13.5 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RLN68797.1 - 0.15 11.8 0.1 0.37 10.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN68797.1 - 0.2 11.2 0.1 0.36 10.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 RLN68797.1 - 0.2 11.8 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AhpC-TSA PF00578.21 RLN68811.1 - 1.6e-08 34.5 0.0 7.5e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 RLN68811.1 - 1.3e-07 31.8 0.0 4.4e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 RLN68811.1 - 0.0012 18.6 0.0 0.002 17.8 0.0 1.5 1 1 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 RLN68811.1 - 0.074 13.5 0.0 0.22 12.0 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin PF00085.20 RLN68811.1 - 0.15 12.1 0.0 0.51 10.3 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin Pkinase PF00069.25 RLN68812.1 - 4.7e-07 29.4 0.0 2.3e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN68812.1 - 1.8e-06 27.4 0.0 5.5e-06 25.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase DUF2408 PF10303.9 RLN68813.1 - 2 9.0 9.0 4.4 7.9 8.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) 3HCDH_N PF02737.18 RLN68813.1 - 4.2 7.2 8.2 3.9 7.3 2.7 2.2 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ATP-grasp_2 PF08442.10 RLN68814.1 - 7.1e-51 172.6 0.5 6.4e-49 166.3 0.0 2.9 2 1 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 RLN68814.1 - 8.7e-23 80.8 1.5 8.7e-23 80.8 1.5 1.6 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 RLN68814.1 - 9.3e-06 25.2 0.5 0.11 11.9 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain Succ_CoA_lig PF13607.6 RLN68814.1 - 0.035 13.9 0.4 0.12 12.2 0.2 1.8 1 1 1 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain Arf PF00025.21 RLN68815.1 - 3.4e-69 231.8 0.3 3.8e-69 231.6 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 RLN68815.1 - 3.6e-13 49.4 0.6 1.1e-08 34.6 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 RLN68815.1 - 6e-13 48.7 0.0 7e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 RLN68815.1 - 8e-13 48.2 0.0 9.4e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 RLN68815.1 - 1.8e-11 44.3 0.0 2.5e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 RLN68815.1 - 1.1e-08 34.8 0.0 1.3e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RLN68815.1 - 1.8e-05 24.8 0.0 2.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 RLN68815.1 - 0.007 16.8 0.0 0.01 16.2 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 RLN68815.1 - 0.027 14.2 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 RLN68815.1 - 0.031 14.8 0.0 0.055 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain HSA PF07529.13 RLN68816.1 - 2e-09 37.6 6.2 3.8e-08 33.6 6.2 2.7 1 1 0 1 1 1 1 HSA SNF2_N PF00176.23 RLN68816.1 - 5.5e-09 35.2 0.8 9.7e-08 31.1 0.8 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Myb_DNA-bind_6 PF13921.6 RLN68816.1 - 3.3e-06 27.3 0.0 1.1e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 RLN68816.1 - 5.8e-06 26.4 0.0 1.8e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain CCDC23 PF15674.5 RLN68816.1 - 0.01 15.8 0.3 0.043 13.8 0.3 2.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 23 WIYLD PF10440.9 RLN68816.1 - 0.094 12.5 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain zf_C2H2_ZHX PF18387.1 RLN68827.1 - 0.047 13.3 0.4 0.067 12.8 0.4 1.3 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF3301 PF11743.8 RLN68827.1 - 0.052 13.2 0.1 0.067 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) Abhydrolase_3 PF07859.13 RLN68828.1 - 4e-42 144.5 0.0 4.9e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 RLN68828.1 - 0.065 12.1 0.0 0.25 10.2 0.0 1.7 1 1 0 1 1 1 0 Carboxylesterase family BT1 PF03092.16 RLN68829.1 - 1.2e-10 40.3 0.7 1.2e-10 40.3 0.7 2.4 2 0 0 2 2 2 2 BT1 family PUCC PF03209.15 RLN68829.1 - 0.0027 16.8 14.5 0.044 12.8 14.5 2.3 1 1 0 1 1 1 1 PUCC protein DUF4131 PF13567.6 RLN68829.1 - 4.3 7.0 10.3 6 6.5 0.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Cpn60_TCP1 PF00118.24 RLN68831.1 - 6.2e-165 549.5 1.8 7.5e-165 549.3 1.8 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-RING_2 PF13639.6 RLN68831.1 - 1.4e-13 50.9 9.3 2.8e-13 50.0 9.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 RLN68831.1 - 2.9e-08 33.3 6.5 7.3e-08 32.0 6.5 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RLN68831.1 - 1.6e-07 31.0 9.2 3.9e-07 29.8 9.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN68831.1 - 2.3e-06 27.8 8.6 5.2e-06 26.6 8.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RLN68831.1 - 4.6e-06 26.5 7.2 9.2e-06 25.5 7.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RLN68831.1 - 6.7e-05 22.7 7.0 0.00016 21.5 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN68831.1 - 8e-05 22.4 8.8 0.00015 21.5 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN68831.1 - 0.02 14.9 8.3 0.048 13.7 8.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 RLN68831.1 - 0.035 14.0 7.3 0.074 12.9 7.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Baculo_RING PF05883.11 RLN68831.1 - 0.047 13.7 2.9 2.9 7.9 1.3 2.6 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-ANAPC11 PF12861.7 RLN68831.1 - 0.1 12.7 5.9 0.27 11.3 5.9 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 RLN68831.1 - 0.89 9.2 7.6 1.8 8.3 7.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 RLN68831.1 - 6.6 6.5 6.5 15 5.4 6.5 1.5 1 0 0 1 1 1 0 P-11 zinc finger V-SNARE_C PF12352.8 RLN68832.1 - 4.2e-08 33.3 3.5 5.1e-08 33.1 3.5 1.1 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus MMtag PF10159.9 RLN68833.1 - 7.5e-06 26.1 0.2 7.5e-06 26.1 0.2 2.7 2 1 0 2 2 2 1 Multiple myeloma tumor-associated AP3D1 PF06375.11 RLN68833.1 - 0.35 11.1 14.6 0.094 12.9 11.6 1.7 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 BHD_2 PF10404.9 RLN68833.1 - 1.7 9.7 12.8 2.3 9.2 8.8 2.4 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 Pox_Ag35 PF03286.14 RLN68833.1 - 2 8.2 11.0 0.36 10.6 7.5 1.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Vfa1 PF08432.10 RLN68833.1 - 7.1 6.9 14.9 1.4 9.2 10.8 1.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Rtf2 PF04641.12 RLN68833.1 - 10 5.4 14.1 1.8 7.9 10.5 1.5 2 0 0 2 2 2 0 Rtf2 RING-finger PAPS_reduct PF01507.19 RLN68834.1 - 3.5e-26 92.3 0.1 1.1e-16 61.4 0.0 2.9 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family NAD_synthase PF02540.17 RLN68834.1 - 0.06 12.5 0.2 0.29 10.2 0.0 2.0 2 0 0 2 2 2 0 NAD synthase zf-like PF04071.12 RLN68834.1 - 0.23 11.4 0.1 0.23 11.4 0.1 2.0 3 0 0 3 3 3 0 Cysteine-rich small domain DUF676 PF05057.14 RLN68835.1 - 1.5e-21 77.0 0.0 2e-20 73.2 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 RLN68835.1 - 0.00068 20.3 0.2 0.0017 19.0 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 RLN68835.1 - 0.011 15.5 0.0 0.35 10.7 0.0 2.5 2 1 1 3 3 3 0 Palmitoyl protein thioesterase PGAP1 PF07819.13 RLN68835.1 - 0.066 12.9 0.5 0.36 10.5 0.5 1.9 1 1 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 RLN68835.1 - 0.092 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) HECT PF00632.25 RLN68836.1 - 3.1e-76 256.8 0.0 4.3e-76 256.3 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Phage_TAC_5 PF08890.11 RLN68839.1 - 0.094 12.7 0.0 0.11 12.5 0.0 1.0 1 0 0 1 1 1 0 Phage XkdN-like tail assembly chaperone protein, TAC PI3_PI4_kinase PF00454.27 RLN68840.1 - 9.2e-53 179.6 0.1 1.7e-52 178.7 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Abhydrolase_3 PF07859.13 RLN68840.1 - 8e-42 143.5 0.0 2.7e-41 141.7 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold FAT PF02259.23 RLN68840.1 - 1.8e-32 112.9 0.6 7e-32 111.0 0.6 2.2 1 1 0 1 1 1 1 FAT domain UME PF08064.13 RLN68840.1 - 9.6e-22 76.8 0.0 1.2e-19 70.1 0.0 3.5 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.20 RLN68840.1 - 5.5e-12 45.3 0.0 1.6e-11 43.8 0.0 1.9 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.6 RLN68840.1 - 0.0024 18.4 5.6 0.19 12.2 0.0 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat DUF3385 PF11865.8 RLN68840.1 - 0.0062 16.5 0.0 0.035 14.0 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) TPR_1 PF00515.28 RLN68840.1 - 0.015 15.1 2.7 2.3 8.2 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN68840.1 - 0.032 14.3 2.4 2.7 8.3 0.3 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 RLN68840.1 - 0.12 12.5 0.1 0.61 10.2 0.1 2.3 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 RLN68840.1 - 0.31 10.8 2.0 7.5 6.3 0.8 2.9 3 0 0 3 3 3 0 TPR repeat WD40 PF00400.32 RLN68841.1 - 1.1e-63 209.6 74.1 0.00067 20.4 0.2 27.9 28 0 0 28 28 28 19 WD domain, G-beta repeat HELP PF03451.14 RLN68841.1 - 9.3e-54 179.2 0.3 7.2e-20 70.6 0.1 3.7 3 0 0 3 3 3 3 HELP motif ANAPC4_WD40 PF12894.7 RLN68841.1 - 1.6e-27 95.6 5.1 2.8e-05 24.3 0.0 14.2 12 4 5 17 17 17 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN68841.1 - 2.1e-07 30.2 0.1 0.15 11.0 0.0 4.8 5 1 0 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 RLN68841.1 - 0.00014 21.1 0.0 0.11 11.5 0.0 3.3 4 0 0 4 4 4 2 VID27 C-terminal WD40-like domain eIF2A PF08662.11 RLN68841.1 - 0.003 17.5 0.1 6.7 6.5 0.0 5.3 7 0 0 7 7 7 1 Eukaryotic translation initiation factor eIF2A EF-hand_7 PF13499.6 RLN68841.1 - 0.026 15.0 0.0 0.13 12.7 0.2 2.1 2 0 0 2 2 2 0 EF-hand domain pair PD40 PF07676.12 RLN68841.1 - 0.029 14.3 0.2 13 5.9 0.0 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 RLN68841.1 - 0.039 12.7 0.0 2.8 6.6 0.0 3.9 4 0 0 4 4 4 0 Nup133 N terminal like EF-hand_8 PF13833.6 RLN68841.1 - 0.2 11.5 0.2 0.74 9.7 0.2 2.0 1 0 0 1 1 1 0 EF-hand domain pair SUI1 PF01253.22 RLN68842.1 - 2.6e-23 82.3 0.4 3.3e-23 82.0 0.4 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2997 PF11211.8 RLN68842.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2997) DUF1279 PF06916.13 RLN68843.1 - 1.7e-05 25.2 0.0 3.4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) bZIP_2 PF07716.15 RLN68843.1 - 0.0019 18.2 0.1 0.0029 17.6 0.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper Cnn_1N PF07989.11 RLN68843.1 - 0.0027 17.8 0.4 0.0044 17.2 0.4 1.2 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 DivIC PF04977.15 RLN68843.1 - 0.031 14.0 0.9 0.053 13.3 0.9 1.3 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.21 RLN68843.1 - 0.041 14.0 0.8 0.062 13.4 0.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor DUF848 PF05852.11 RLN68843.1 - 0.1 12.7 0.2 0.17 12.0 0.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) TSC22 PF01166.18 RLN68843.1 - 0.1 12.9 0.5 0.2 12.0 0.5 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF4407 PF14362.6 RLN68843.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HALZ PF02183.18 RLN68843.1 - 0.31 11.3 1.5 0.46 10.8 1.5 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper ABC_membrane PF00664.23 RLN68925.1 - 3.1e-60 204.1 31.0 7.5e-36 124.2 8.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN68925.1 - 2e-20 73.7 0.6 7.2e-19 68.7 0.0 2.5 2 0 0 2 2 2 1 ABC transporter Dynamin_N PF00350.23 RLN68925.1 - 0.00039 20.5 0.0 0.00071 19.7 0.0 1.4 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 RLN68925.1 - 0.0019 18.2 0.9 0.0044 17.0 0.2 1.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 RLN68925.1 - 0.0032 17.5 0.0 0.0076 16.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 RLN68925.1 - 0.0067 16.3 0.6 2.7 7.7 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN68925.1 - 0.0073 16.0 0.2 0.024 14.4 0.2 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 RLN68925.1 - 0.0081 15.6 0.5 0.58 9.6 0.2 2.4 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RLN68925.1 - 0.028 14.8 0.0 0.078 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 RLN68925.1 - 0.12 11.6 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 RLN68926.1 - 1.9e-29 103.0 0.0 3.1e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN68926.1 - 3.7e-07 29.8 0.0 6.4e-05 22.5 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 RLN68926.1 - 0.0006 19.6 0.0 0.00096 18.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 RLN68926.1 - 0.0027 17.5 0.1 0.0096 15.7 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF87 PF01935.17 RLN68926.1 - 0.01 15.9 0.4 0.06 13.4 0.1 2.1 2 1 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 RLN68926.1 - 0.012 15.6 0.2 0.03 14.4 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 RLN68926.1 - 0.018 14.8 0.3 0.36 10.5 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 RLN68926.1 - 0.091 12.5 0.1 0.62 9.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RLN68926.1 - 0.12 12.2 0.1 0.28 11.0 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN68926.1 - 0.12 12.9 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Homoserine_dh PF00742.19 RLN68938.1 - 5.2e-39 133.9 0.0 1.3e-38 132.6 0.0 1.7 2 0 0 2 2 2 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 RLN68938.1 - 5.9e-07 30.2 0.0 2.1e-06 28.4 0.0 2.0 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 RLN68938.1 - 0.038 14.2 0.0 0.094 13.0 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF4148 PF13663.6 RLN68939.1 - 0.22 11.7 11.2 0.22 11.7 2.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) FIST PF08495.10 RLN68946.1 - 2.4e-15 57.0 0.2 4.7e-15 56.0 0.2 1.5 1 0 0 1 1 1 1 FIST N domain FIST_C PF10442.9 RLN68946.1 - 0.0015 18.5 0.0 0.0035 17.3 0.0 1.6 1 0 0 1 1 1 1 FIST C domain DEAD PF00270.29 RLN68947.1 - 4.7e-50 169.8 0.0 1.6e-49 168.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN68947.1 - 2.3e-25 89.1 0.0 1.9e-24 86.1 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.14 RLN68947.1 - 0.017 14.4 0.0 0.017 14.4 0.0 3.1 3 1 0 3 3 3 0 SecA DEAD-like domain BBS1 PF14779.6 RLN68948.1 - 4.4e-60 203.3 0.1 1.8e-46 158.7 0.0 2.8 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.6 RLN68948.1 - 0.054 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region zf-B_box PF00643.24 RLN68951.1 - 3.9e-05 23.7 31.7 0.011 15.9 13.3 2.5 2 0 0 2 2 2 2 B-box zinc finger EzrA PF06160.12 RLN68951.1 - 0.0022 16.2 0.4 0.0034 15.7 0.4 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA CEBP_ZZ PF16366.5 RLN68951.1 - 0.0072 16.5 27.1 0.29 11.4 12.2 2.6 2 0 0 2 2 2 2 Cytoplasmic polyadenylation element-binding protein ZZ domain C1_4 PF07975.12 RLN68951.1 - 0.017 15.4 4.7 0.017 15.4 4.7 3.1 2 1 0 2 2 2 0 TFIIH C1-like domain Ank_2 PF12796.7 RLN68952.1 - 3.2e-37 127.0 12.7 4e-10 40.1 0.1 6.0 2 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN68952.1 - 3.9e-37 126.2 18.0 6.3e-06 26.6 0.1 9.3 5 2 4 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN68952.1 - 9e-33 111.9 22.8 0.00063 20.0 0.1 12.8 4 2 10 14 14 14 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN68952.1 - 2.5e-23 79.6 8.6 0.12 13.0 0.1 12.7 9 3 4 13 13 13 4 Ankyrin repeat DUF5049 PF16468.5 RLN68952.1 - 8e-08 32.1 0.1 4.8 7.2 0.0 8.9 4 3 7 11 11 11 1 Domain of unknown function (DUF5049) Ank PF00023.30 RLN68952.1 - 2.6e-06 27.6 4.5 6.9 7.3 0.0 8.4 4 2 4 8 8 8 1 Ankyrin repeat DUF4411 PF14367.6 RLN68952.1 - 0.015 15.2 0.2 5.2 6.9 0.0 3.3 1 1 1 3 3 3 0 Domain of unknown function (DUF4411) DUF1843 PF08898.10 RLN68952.1 - 0.03 14.8 0.8 6.8 7.3 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) CNOT1_HEAT PF16418.5 RLN68952.1 - 0.62 10.1 2.5 73 3.4 0.1 5.0 5 1 1 6 6 6 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Ank_2 PF12796.7 RLN68953.1 - 5.6e-34 116.6 16.0 3.6e-08 33.9 0.4 6.3 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN68953.1 - 1.2e-31 108.6 20.2 1.3e-05 25.7 0.1 9.7 10 1 0 10 10 10 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN68953.1 - 4.3e-30 103.4 22.1 6.5e-05 23.1 0.0 11.6 5 3 7 12 12 12 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN68953.1 - 1.1e-13 50.0 12.3 2 9.2 0.0 12.4 11 1 2 13 13 13 2 Ankyrin repeat Ank PF00023.30 RLN68953.1 - 0.00035 20.9 9.6 10 6.8 0.1 7.8 6 3 1 7 7 7 1 Ankyrin repeat DUF5049 PF16468.5 RLN68953.1 - 0.00037 20.3 0.0 67 3.5 0.0 6.7 5 2 3 8 8 8 0 Domain of unknown function (DUF5049) DHC PF09626.10 RLN68953.1 - 0.015 16.2 0.0 0.075 13.9 0.0 2.2 1 0 0 1 1 1 0 Dihaem cytochrome c DUF3322 PF11795.8 RLN68953.1 - 0.03 14.3 7.7 1.2 9.1 0.1 5.0 4 2 1 5 5 5 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) GUN4 PF05419.12 RLN68953.1 - 0.12 12.4 1.3 12 5.9 0.1 3.4 3 0 0 3 3 3 0 GUN4-like VWA_3_C PF18571.1 RLN68953.1 - 0.15 12.0 4.2 5.3 7.0 0.2 4.6 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain CNOT1_HEAT PF16418.5 RLN68953.1 - 0.43 10.6 10.1 51 3.9 0.1 6.6 7 2 1 8 8 8 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Pyrid_oxidase_2 PF13883.6 RLN68956.1 - 2.4e-08 34.1 0.4 6.2e-08 32.8 0.4 1.7 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CFAP91 PF14738.6 RLN68956.1 - 0.005 16.9 12.1 0.0089 16.1 12.1 1.3 1 0 0 1 1 1 1 Cilia- and flagella-associated protein 91 DUF720 PF05302.11 RLN68956.1 - 0.47 10.3 13.4 0.93 9.4 13.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Presenilin PF01080.17 RLN68956.1 - 4.9 5.8 5.0 7.3 5.2 5.0 1.2 1 0 0 1 1 1 0 Presenilin Oxidored_FMN PF00724.20 RLN68957.1 - 5e-86 289.1 0.0 5.7e-86 288.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Aldose_epim PF01263.20 RLN68958.1 - 5e-36 124.6 0.3 6.2e-36 124.2 0.3 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DUF4165 PF13752.6 RLN68959.1 - 0.1 12.6 0.0 0.38 10.7 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4165) Ferric_reduct PF01794.19 RLN69043.1 - 2.9e-19 69.4 16.6 2.9e-19 69.4 16.6 3.1 3 1 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 RLN69043.1 - 1e-09 38.7 0.0 1.7e-09 38.0 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 RLN69043.1 - 2.1e-09 37.4 0.0 4.8e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain TM1506 PF08973.10 RLN69043.1 - 0.011 15.5 0.6 0.026 14.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1893) WTF PF03303.13 RLN69043.1 - 8.5 6.0 14.0 0.28 10.9 0.1 3.7 3 1 1 4 4 4 0 WTF protein PCO_ADO PF07847.12 RLN69055.1 - 1.3e-21 77.0 0.0 4.7e-21 75.2 0.0 1.9 1 1 0 1 1 1 1 PCO_ADO Cupin_2 PF07883.11 RLN69055.1 - 0.29 10.9 0.0 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 Cupin domain Med3 PF11593.8 RLN69055.1 - 2.3 7.3 12.6 6.4 5.9 0.1 2.4 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal zf-C3HC4 PF00097.25 RLN69056.1 - 1e-08 34.9 10.3 1.7e-08 34.1 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RLN69056.1 - 3.5e-08 33.5 11.6 6.1e-08 32.7 11.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 RLN69056.1 - 5.4e-08 32.5 12.1 9.6e-08 31.7 12.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN69056.1 - 1.3e-07 31.5 7.5 1.3e-07 31.5 7.5 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN69056.1 - 3.8e-06 26.7 13.2 6.7e-06 26.0 13.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RLN69056.1 - 4.1e-06 26.5 13.3 6.8e-06 25.8 13.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 RLN69056.1 - 4.3e-06 26.5 4.5 8.1e-06 25.6 4.5 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 RLN69056.1 - 2.1e-05 24.7 12.0 3.9e-05 23.9 12.0 1.5 1 0 0 1 1 1 1 Ring finger domain U-box PF04564.15 RLN69056.1 - 0.0019 18.3 0.0 0.004 17.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-ANAPC11 PF12861.7 RLN69056.1 - 0.0063 16.5 8.4 0.011 15.8 8.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 RLN69056.1 - 0.035 13.9 8.0 0.035 13.9 8.0 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF4604 PF15377.6 RLN69056.1 - 0.14 12.6 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Prok-RING_4 PF14447.6 RLN69056.1 - 0.28 11.1 17.2 0.099 12.5 14.5 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 RLN69056.1 - 0.57 10.5 11.3 1.3 9.4 11.3 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-UDP PF14569.6 RLN69056.1 - 4.4 7.5 9.3 12 6.0 9.3 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RanBP PF00641.18 RLN69057.1 - 0.02 14.2 7.4 0.035 13.4 7.4 1.3 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others SepF PF04472.12 RLN69057.1 - 0.11 12.8 0.1 0.32 11.3 0.0 1.8 2 0 0 2 2 2 0 Cell division protein SepF Vps36-NZF-N PF16988.5 RLN69057.1 - 0.79 9.2 5.3 8.1 5.9 5.3 2.3 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Ysc84 PF04366.12 RLN69058.1 - 3.1e-32 111.0 0.7 7.1e-32 109.9 0.7 1.6 1 0 0 1 1 1 1 Las17-binding protein actin regulator YL1_C PF08265.11 RLN69058.1 - 0.075 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain AflR PF08493.10 RLN69058.1 - 7.1 6.0 9.9 14 5.0 9.9 1.4 1 0 0 1 1 1 0 Aflatoxin regulatory protein F_bP_aldolase PF01116.20 RLN69059.1 - 9.6e-90 300.8 0.0 1.1e-89 300.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II CPSase_L_D2 PF02786.17 RLN69059.1 - 0.11 12.0 0.5 0.82 9.1 0.2 2.0 1 1 1 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain LRR_4 PF12799.7 RLN69060.1 - 3.7e-17 62.1 7.2 4.4e-05 23.8 0.1 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN69060.1 - 1.4e-16 60.5 4.1 5.2e-15 55.4 2.6 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 RLN69060.1 - 4.5e-09 35.9 15.5 6.8e-05 22.6 0.3 3.2 1 1 3 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 RLN69060.1 - 0.06 13.4 3.5 12 6.2 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 RLN69060.1 - 0.22 12.2 4.2 1.5e+02 3.6 0.1 5.1 5 0 0 5 5 5 0 Leucine Rich Repeat DUF5401 PF17380.2 RLN69060.1 - 3.8 5.5 16.4 5.2 5.0 16.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) His_Phos_2 PF00328.22 RLN69061.1 - 3e-25 89.4 0.1 5.8e-25 88.5 0.1 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF5375 PF17345.2 RLN69061.1 - 0.093 12.6 0.3 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5375) DisA_N PF02457.16 RLN69061.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding AstE_AspA PF04952.14 RLN69062.1 - 6e-15 55.1 0.4 1.4e-14 53.9 0.4 1.5 1 1 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family GCIP PF13324.6 RLN69063.1 - 2.1e-15 57.0 2.7 4.6e-11 42.8 0.7 3.3 4 0 0 4 4 4 2 Grap2 and cyclin-D-interacting CPDase PF07823.11 RLN69063.1 - 0.0064 16.2 0.0 0.36 10.5 0.0 2.7 2 1 1 3 3 3 1 Cyclic phosphodiesterase-like protein EF-hand_1 PF00036.32 RLN69064.1 - 2.5e-23 79.8 7.5 4.5e-07 29.0 0.5 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 RLN69064.1 - 1.1e-18 67.5 4.9 2e-12 47.3 0.4 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN69064.1 - 4.1e-16 57.5 7.6 1.9e-05 24.3 0.0 4.6 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 RLN69064.1 - 5.5e-13 47.8 5.5 0.00013 21.3 0.3 3.9 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RLN69064.1 - 1.3e-12 47.4 5.9 3.5e-06 26.7 0.2 3.4 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 RLN69064.1 - 7.2e-06 26.2 0.1 0.00037 20.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_11 PF08976.11 RLN69064.1 - 0.011 16.5 0.1 0.65 10.9 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain FGAR-AT_linker PF18072.1 RLN69064.1 - 0.031 14.8 0.0 0.1 13.2 0.0 1.9 1 1 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase linker domain SurA_N_3 PF13624.6 RLN69064.1 - 0.042 13.7 0.2 0.069 12.9 0.2 1.3 1 0 0 1 1 1 0 SurA N-terminal domain UPF0154 PF03672.13 RLN69064.1 - 0.18 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) DUF547 PF04784.14 RLN69065.1 - 1e-21 77.3 0.0 2.2e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 eIF3_subunit PF08597.10 RLN69065.1 - 0.72 9.7 7.1 1.3 8.9 7.1 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit NTP_transf_2 PF01909.23 RLN69066.1 - 3.2e-09 36.9 0.0 5.9e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 RLN69066.1 - 2.9e-06 27.4 0.0 6.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase tRNA_NucTransf2 PF09249.11 RLN69066.1 - 0.0099 16.1 0.0 0.56 10.5 0.0 2.5 2 0 0 2 2 2 1 tRNA nucleotidyltransferase, second domain DNA_pol_B_palm PF14792.6 RLN69066.1 - 0.039 14.2 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase beta palm Polbeta PF18765.1 RLN69066.1 - 0.18 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Radical_SAM PF04055.21 RLN69067.1 - 9.7e-12 45.6 0.0 1.9e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 RLN69067.1 - 0.00044 20.4 0.0 0.00094 19.3 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 RLN69067.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 4Fe-4S single cluster domain Nefa_Nip30_N PF10187.9 RLN69068.1 - 1.9e-11 44.2 6.6 1.9e-11 44.2 6.6 2.8 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 RLN69068.1 - 0.00035 20.3 4.5 0.00049 19.8 4.5 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF4407 PF14362.6 RLN69069.1 - 0.034 13.5 2.5 0.06 12.7 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAA_hydrolase_N PF09298.11 RLN69069.1 - 0.13 12.5 0.3 0.23 11.6 0.3 1.5 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal MutS_V PF00488.21 RLN69070.1 - 1e-78 263.7 0.1 1.7e-78 262.9 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 RLN69070.1 - 1e-24 87.9 0.1 2.1e-24 86.8 0.1 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 RLN69070.1 - 1.2e-08 35.2 0.0 2.2e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 RLN69070.1 - 0.0035 17.6 0.1 0.018 15.3 0.0 2.2 2 0 0 2 2 2 1 MutS domain II AAA_28 PF13521.6 RLN69070.1 - 0.012 15.9 0.4 0.043 14.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 RLN69070.1 - 0.018 14.6 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 RLN69070.1 - 0.045 13.7 0.6 6.9 6.5 0.0 3.5 3 0 0 3 3 3 0 NTPase DUF5527 PF17665.1 RLN69073.1 - 0.012 15.2 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Gemini_mov PF01708.16 RLN69073.1 - 0.015 15.0 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Geminivirus putative movement protein DUF4577 PF15145.6 RLN69073.1 - 0.02 14.9 0.0 0.02 14.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) Plant_vir_prot PF01307.17 RLN69073.1 - 0.13 12.5 0.4 0.27 11.5 0.4 1.6 1 1 0 1 1 1 0 Plant viral movement protein APG6_N PF17675.1 RLN69178.1 - 1.7 9.2 15.6 8.5 6.9 1.3 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region Beta-Casp PF10996.8 RLN69188.1 - 1.4e-31 109.0 0.0 3.2e-31 107.9 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 RLN69188.1 - 2.9e-22 79.1 0.0 6e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 RLN69188.1 - 8.9e-21 74.8 0.6 1.6e-20 74.0 0.2 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 RLN69188.1 - 2e-17 62.9 0.0 4.4e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 RLN69188.1 - 6.3e-10 38.9 0.2 1.4e-09 37.8 0.2 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 RLN69188.1 - 5.2e-06 26.5 0.1 2.5e-05 24.2 0.1 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 RLN69188.1 - 5.4e-06 25.8 0.0 9.9e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Putative beta-lactamase-like family DUF2089 PF09862.9 RLN69192.1 - 0.057 13.5 0.1 0.076 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) TPR_1 PF00515.28 RLN69194.1 - 1.6e-26 91.0 6.5 1.3e-07 31.2 0.0 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 RLN69194.1 - 5.6e-25 85.4 8.0 0.00026 20.9 0.0 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN69194.1 - 1.2e-19 70.3 11.2 2.1e-14 53.5 0.1 4.2 5 1 0 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 RLN69194.1 - 3.2e-19 69.3 0.5 7e-07 29.8 0.0 6.0 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN69194.1 - 6.9e-19 66.4 0.1 0.0006 19.8 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 RLN69194.1 - 1.4e-17 64.0 3.9 0.0059 17.1 0.1 6.6 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 RLN69194.1 - 5.7e-16 58.6 8.1 0.041 14.2 0.2 6.9 5 2 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 RLN69194.1 - 7.9e-16 57.4 4.1 0.018 15.8 0.0 7.0 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 RLN69194.1 - 6e-15 54.6 0.9 8.8e-09 34.9 0.3 4.3 4 0 0 4 4 4 2 TPR repeat TPR_17 PF13431.6 RLN69194.1 - 1.1e-11 44.2 3.8 0.0021 18.3 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN69194.1 - 6.4e-11 41.5 6.0 0.15 12.1 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 RLN69194.1 - 1.6e-10 40.9 4.3 2.6 8.9 0.0 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN69194.1 - 0.00031 20.8 0.0 0.019 15.1 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN69194.1 - 0.012 15.4 3.0 67 3.6 0.0 5.9 8 0 0 8 8 8 0 Tetratricopeptide repeat ChAPs PF09295.10 RLN69194.1 - 0.022 13.7 0.0 1.2 8.0 0.0 2.2 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) PPTA PF01239.22 RLN69194.1 - 0.076 12.8 0.1 0.51 10.2 0.1 2.4 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat FAT PF02259.23 RLN69194.1 - 0.32 10.2 2.5 4.4 6.4 1.1 3.0 2 1 0 2 2 2 0 FAT domain FoP_duplication PF13865.6 RLN69195.1 - 5.1e-19 68.6 9.0 5.1e-19 68.6 9.0 3.4 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 GvpL_GvpF PF06386.11 RLN69195.1 - 0.31 10.9 6.2 0.48 10.3 6.2 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Spt20 PF12090.8 RLN69195.1 - 3.6 7.1 18.9 6.8 6.2 18.9 1.5 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 RLN69195.1 - 4 6.1 6.3 5 5.8 6.3 1.2 1 0 0 1 1 1 0 Presenilin EXOSC1 PF10447.9 RLN69197.1 - 0.074 13.7 0.9 0.13 12.9 0.9 1.4 1 0 0 1 1 1 0 Exosome component EXOSC1/CSL4 RasGAP PF00616.19 RLN69198.1 - 6.8e-25 88.0 0.0 2.7e-21 76.3 0.0 3.3 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase PH PF00169.29 RLN69198.1 - 0.00029 21.3 0.0 0.00061 20.3 0.0 1.5 1 0 0 1 1 1 1 PH domain HABP4_PAI-RBP1 PF04774.15 RLN69199.1 - 1.5e-14 54.8 8.3 6e-14 52.9 8.3 2.0 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family MORN PF02493.20 RLN69200.1 - 8.3e-37 122.9 54.9 9.1e-07 28.4 0.6 10.9 11 0 0 11 11 11 9 MORN repeat HSDR_N_2 PF13588.6 RLN69290.1 - 0.0089 16.0 0.1 0.016 15.2 0.1 1.5 1 1 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) bZIP_1 PF00170.21 RLN69294.1 - 0.0039 17.3 6.0 0.0087 16.1 6.0 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RLN69294.1 - 0.007 16.4 6.4 0.014 15.4 6.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper DUF4618 PF15397.6 RLN69294.1 - 0.069 12.6 0.9 0.75 9.2 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF3450 PF11932.8 RLN69294.1 - 0.069 12.4 0.3 0.11 11.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) bZIP_Maf PF03131.17 RLN69294.1 - 0.25 11.9 4.1 0.49 11.0 4.1 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF4340 PF14238.6 RLN69296.1 - 0.11 12.5 0.1 0.5 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4340) FYVE PF01363.21 RLN69298.1 - 2.5e-10 40.4 15.0 5e-10 39.4 15.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger Nudix_N_2 PF14803.6 RLN69298.1 - 0.038 13.9 1.5 0.038 13.9 1.5 2.9 2 1 0 2 2 2 0 Nudix N-terminal C1_2 PF03107.16 RLN69298.1 - 0.97 9.8 11.0 0.18 12.1 6.9 1.9 2 0 0 2 2 2 0 C1 domain E1_dh PF00676.20 RLN69299.1 - 7.6e-103 343.6 0.1 9.6e-103 343.2 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 RLN69299.1 - 0.011 15.0 0.5 0.018 14.2 0.1 1.6 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.21 RLN69299.1 - 0.065 12.2 0.0 0.097 11.6 0.0 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain UCH PF00443.29 RLN69300.1 - 6e-25 88.2 0.5 1.1e-24 87.3 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 RLN69300.1 - 5.3e-14 52.3 1.5 9.6e-14 51.5 1.5 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 RLN69300.1 - 0.0037 16.9 0.6 0.014 15.0 0.0 2.1 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 RLN69300.1 - 0.12 12.2 1.1 0.26 11.1 0.3 1.9 2 0 0 2 2 2 0 Variant UBP zinc finger DED PF01335.21 RLN69300.1 - 0.13 12.6 0.0 8.3 6.8 0.1 2.5 2 1 0 2 2 2 0 Death effector domain MIT PF04212.18 RLN69301.1 - 1.7e-12 47.2 6.3 3.3e-12 46.3 6.3 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 RLN69301.1 - 4.2e-11 42.5 0.6 2e-09 37.1 0.1 2.8 2 1 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 RLN69301.1 - 2.3e-05 24.8 0.1 4.9e-05 23.8 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 RLN69301.1 - 0.00083 19.3 0.0 0.0023 17.9 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain ProQ PF04352.13 RLN69301.1 - 0.11 12.3 2.8 0.19 11.6 1.5 2.0 2 0 0 2 2 2 0 ProQ/FINO family Use1 PF09753.9 RLN69301.1 - 0.4 10.4 5.2 0.57 9.9 5.2 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 PG_binding_3 PF09374.10 RLN69302.1 - 0.029 14.6 0.0 0.09 13.0 0.0 1.8 1 0 0 1 1 1 0 Predicted Peptidoglycan domain PP2C PF00481.21 RLN69303.1 - 4.7e-48 164.1 0.0 2.9e-45 154.9 0.0 2.2 1 1 0 2 2 2 2 Protein phosphatase 2C GIT_CC PF16559.5 RLN69303.1 - 0.021 14.7 1.7 0.051 13.5 1.7 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Myc_N PF01056.18 RLN69303.1 - 1.7 8.5 5.1 0.31 10.9 0.8 1.8 2 0 0 2 2 2 0 Myc amino-terminal region FlxA PF14282.6 RLN69303.1 - 1.8 8.6 10.8 5.3 7.1 10.7 1.9 1 1 0 1 1 1 0 FlxA-like protein DUF3886 PF13025.6 RLN69303.1 - 2.5 8.4 6.0 0.51 10.6 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) DUF4298 PF14131.6 RLN69303.1 - 3.4 7.7 4.9 5.4 7.0 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) DUF667 PF05018.13 RLN69304.1 - 1.4e-28 99.9 0.0 3e-28 98.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF667) UCR_Fe-S_N PF10399.9 RLN69305.1 - 0.0058 16.0 2.5 0.0058 16.0 2.5 2.2 2 0 0 2 2 2 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Na_H_Exchanger PF00999.21 RLN69306.1 - 9.3e-50 169.5 41.1 1.1e-49 169.3 41.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family LapA_dom PF06305.11 RLN69306.1 - 0.9 9.4 0.0 0.9 9.4 0.0 3.7 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain zf-UBR PF02207.20 RLN69307.1 - 7.2e-17 61.3 14.3 7.2e-17 61.3 14.3 2.2 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 RLN69307.1 - 5.6e-06 26.1 0.0 5.6e-06 26.1 0.0 2.9 3 0 0 3 3 3 1 ATP-dependent Clp protease adaptor protein ClpS Mistic PF11458.8 RLN69307.1 - 0.11 12.5 0.8 0.26 11.3 0.8 1.5 1 0 0 1 1 1 0 Membrane-integrating protein Mistic Bin3 PF06859.12 RLN69308.1 - 2.9e-16 60.0 0.1 6.8e-16 58.8 0.1 1.7 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) dsrm PF00035.26 RLN69308.1 - 4.1e-14 53.0 0.0 7.6e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Methyltransf_31 PF13847.6 RLN69308.1 - 9.2e-07 28.8 0.0 0.004 17.0 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 RLN69308.1 - 2.4e-05 24.9 0.1 0.057 14.1 0.1 3.2 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 RLN69308.1 - 9.5e-05 22.3 0.0 0.0019 18.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 RLN69308.1 - 9.7e-05 22.5 0.7 0.038 14.1 0.7 2.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 RLN69308.1 - 0.00023 21.8 0.1 2.6 8.8 0.1 3.3 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 RLN69308.1 - 0.0096 16.7 0.0 0.71 10.6 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Requiem_N PF14051.6 RLN69308.1 - 0.088 13.0 0.1 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 N-terminal domain of DPF2/REQ. Glyco_hydro_3_C PF01915.22 RLN69308.1 - 0.14 12.1 0.3 0.18 11.7 0.3 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Na_H_Exchanger PF00999.21 RLN69309.1 - 4.8e-54 183.6 37.9 6.1e-54 183.3 37.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SURF1 PF02104.15 RLN69309.1 - 4.2e-09 36.9 0.0 2.3e-07 31.2 0.0 2.4 1 1 0 1 1 1 1 SURF1 family SURF2 PF05477.11 RLN69309.1 - 0.42 10.3 2.4 0.68 9.6 2.4 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Endosulfine PF04667.17 RLN69310.1 - 3.3e-06 27.1 3.6 0.0074 16.4 0.1 2.8 2 1 1 3 3 3 2 cAMP-regulated phosphoprotein/endosulfine conserved region EFP_N PF08207.12 RLN69311.1 - 1.1e-16 60.5 3.1 2.7e-12 46.5 0.1 2.5 3 0 0 3 3 3 2 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 RLN69311.1 - 3.8e-06 26.8 0.2 5.9e-06 26.2 0.2 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain ABC_membrane PF00664.23 RLN69316.1 - 2.4e-54 184.9 2.1 3.1e-54 184.5 2.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN69316.1 - 8.8e-07 29.5 0.2 1.6e-06 28.7 0.2 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 RLN69316.1 - 0.0003 20.4 0.1 0.00082 19.1 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN69316.1 - 0.042 13.8 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 RLN69316.1 - 0.11 12.9 0.3 0.22 11.9 0.3 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 RLN69316.1 - 0.19 11.2 0.1 0.32 10.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2207 PF09972.9 RLN69316.1 - 0.29 9.9 3.7 0.19 10.5 0.7 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TraL PF07178.11 RLN69316.1 - 0.79 10.2 0.0 0.79 10.2 0.0 3.5 4 0 0 4 4 4 0 TraL protein MtrF PF09472.10 RLN69316.1 - 4.6 6.7 7.0 1.9 7.9 2.0 2.5 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) ABC2_membrane PF01061.24 RLN69392.1 - 1.1e-43 149.1 34.3 2.8e-40 138.0 27.5 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN69392.1 - 1.7e-34 119.3 0.2 4e-16 59.8 0.1 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN69392.1 - 2.2e-07 31.0 0.0 0.06 13.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN69392.1 - 5e-07 30.2 0.1 0.031 14.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 RLN69392.1 - 8.8e-07 29.0 1.0 0.0053 16.7 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 RLN69392.1 - 2e-06 27.4 4.1 0.014 15.1 0.6 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN69392.1 - 1e-05 25.2 0.1 0.045 13.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN69392.1 - 4.7e-05 22.8 0.7 0.0072 15.6 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 RLN69392.1 - 0.00012 22.4 0.1 0.3 11.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 RLN69392.1 - 0.0004 20.2 0.3 0.61 9.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RLN69392.1 - 0.00086 19.9 0.5 0.33 11.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RLN69392.1 - 0.002 18.6 0.3 3.7 8.0 0.2 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 RLN69392.1 - 0.0032 17.0 1.4 1.1 8.7 0.2 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 RLN69392.1 - 0.0078 16.2 0.1 0.32 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 RLN69392.1 - 0.009 16.6 0.1 7.7 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 RLN69392.1 - 0.012 15.5 0.3 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 NACHT PF05729.12 RLN69392.1 - 0.022 14.7 4.2 2.5 8.0 0.1 2.6 2 0 0 2 2 2 0 NACHT domain G-alpha PF00503.20 RLN69392.1 - 0.026 13.7 0.1 0.13 11.4 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit ATPase_2 PF01637.18 RLN69392.1 - 0.03 14.2 0.0 2.1 8.2 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 RLN69392.1 - 0.033 14.2 0.8 0.77 9.8 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 RLN69392.1 - 0.034 13.7 2.5 0.82 9.2 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 RLN69392.1 - 0.037 13.8 1.5 1.8 8.3 0.2 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 RLN69392.1 - 0.041 14.0 3.0 4.4 7.4 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_ATPase PF09818.9 RLN69392.1 - 0.046 12.5 0.4 3.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_33 PF13671.6 RLN69392.1 - 0.049 13.8 0.1 7 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RLN69392.1 - 0.062 13.7 0.5 10 6.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 RLN69392.1 - 0.078 12.7 1.0 13 5.5 0.6 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 RLN69392.1 - 0.086 13.1 0.5 16 5.7 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 RLN69392.1 - 0.1 12.9 0.5 8.2 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 RLN69392.1 - 0.11 11.8 1.1 2.6 7.4 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 RLN69392.1 - 0.19 11.2 1.3 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region MCM PF00493.23 RLN69392.1 - 0.31 10.1 1.1 2.4 7.2 0.0 2.5 3 0 0 3 3 3 0 MCM P-loop domain PDR_CDR PF06422.12 RLN69392.1 - 0.56 10.1 4.4 0.89 9.5 1.0 2.7 3 0 0 3 3 2 0 CDR ABC transporter DUF87 PF01935.17 RLN69392.1 - 2.6 8.1 7.3 8.7 6.4 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain PDR_assoc PF08370.11 RLN69392.1 - 3 7.7 7.4 0.34 10.7 0.8 2.4 2 0 0 2 2 2 0 Plant PDR ABC transporter associated ABC2_membrane_3 PF12698.7 RLN69392.1 - 5.1 6.1 34.3 0.11 11.5 26.0 2.2 2 1 0 2 2 2 0 ABC-2 family transporter protein LCAT PF02450.15 RLN69393.1 - 1.7e-76 257.9 0.0 5.3e-76 256.3 0.0 1.8 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.18 RLN69393.1 - 0.0079 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) TPR_14 PF13428.6 RLN69394.1 - 4.5e-07 30.1 5.2 0.017 15.9 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat DGCR6 PF07324.11 RLN69394.1 - 4.4e-06 26.5 1.4 7.3e-06 25.7 1.4 1.2 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein Suf PF05843.14 RLN69394.1 - 3.9e-05 23.8 0.9 7e-05 22.9 0.2 1.8 2 1 0 2 2 2 1 Suppressor of forked protein (Suf) TPR_19 PF14559.6 RLN69394.1 - 0.0019 18.6 4.0 0.026 15.0 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 RLN69394.1 - 0.017 15.1 1.1 0.17 11.9 1.1 2.5 1 1 0 1 1 1 0 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 RLN69394.1 - 0.035 14.2 5.3 4 7.8 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Cpn60_TCP1 PF00118.24 RLN69395.1 - 2.8e-17 62.5 0.1 3.1e-17 62.4 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2353 PF09789.9 RLN69401.1 - 0.18 11.1 8.5 3 7.1 2.4 2.4 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) HMMR_N PF15905.5 RLN69401.1 - 0.67 9.4 4.7 5.2 6.4 0.1 3.1 3 0 0 3 3 3 0 Hyaluronan mediated motility receptor N-terminal DDE_1 PF03184.19 RLN69414.1 - 4.7e-15 55.7 0.0 7.5e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease GlutR_N PF05201.15 RLN69414.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, N-terminal domain COX6A PF02046.15 RLN69416.1 - 0.1 13.1 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa zf-BED PF02892.15 RLN69417.1 - 0.16 12.0 0.8 0.26 11.3 0.1 1.8 2 0 0 2 2 2 0 BED zinc finger Glyco_trans_2_3 PF13632.6 RLN69417.1 - 0.59 10.0 3.9 0.59 10.0 0.0 2.5 2 1 1 3 3 3 0 Glycosyl transferase family group 2 Gly_reductase PF09338.11 RLN69418.1 - 0.004 15.6 0.0 0.0051 15.3 0.0 1.0 1 0 0 1 1 1 1 Glycine/sarcosine/betaine reductase component B subunits Cpn60_TCP1 PF00118.24 RLN69425.1 - 3.4e-29 101.8 2.1 4.9e-29 101.3 0.6 1.9 2 0 0 2 2 2 1 TCP-1/cpn60 chaperonin family zf-C2H2 PF00096.26 RLN69425.1 - 2.5e-06 27.6 15.4 0.0018 18.6 0.2 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type Lzipper-MIP1 PF14389.6 RLN69425.1 - 0.00022 21.5 1.6 0.096 13.0 0.0 3.4 3 0 0 3 3 3 1 Leucine-zipper of ternary complex factor MIP1 CpXC PF14353.6 RLN69425.1 - 0.0011 19.0 15.7 1.7 8.7 0.9 4.8 4 1 1 5 5 5 3 CpXC protein zf-C2H2_6 PF13912.6 RLN69425.1 - 0.0027 17.7 3.9 1 9.5 0.1 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 RLN69425.1 - 0.011 16.4 0.2 0.011 16.4 0.2 4.8 5 0 0 5 5 5 0 C2H2-type zinc finger YhfH PF14149.6 RLN69425.1 - 0.019 15.0 3.9 0.99 9.4 1.0 2.6 2 0 0 2 2 2 0 YhfH-like protein zf_UBZ PF18439.1 RLN69425.1 - 0.047 13.3 0.5 12 5.6 0.0 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Rpr2 PF04032.16 RLN69425.1 - 0.1 12.9 16.7 0.11 12.8 4.4 3.5 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-H2C2_2 PF13465.6 RLN69425.1 - 0.12 12.9 0.1 0.12 12.9 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double domain IFRD PF05004.13 RLN69426.1 - 1.8e-23 83.1 0.2 3.1e-23 82.4 0.2 1.3 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 RLN69426.1 - 0.0078 16.4 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 HEAT repeat BrnA_antitoxin PF14384.6 RLN69426.1 - 0.066 13.7 0.2 0.96 10.0 0.0 2.6 2 1 0 2 2 2 0 BrnA antitoxin of type II toxin-antitoxin system Eapp_C PF10238.9 RLN69426.1 - 0.14 12.2 3.2 1.3 9.1 0.4 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein HDAC4_Gln PF12203.8 RLN69426.1 - 0.19 11.9 8.1 0.14 12.3 1.6 2.5 2 1 0 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 zf-CCCH PF00642.24 RLN69427.1 - 7.3e-13 48.1 17.1 2.6e-07 30.4 2.3 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 RLN69427.1 - 1.9e-05 25.3 2.5 0.22 12.2 0.2 2.7 2 0 0 2 2 2 2 Torus domain RRM_1 PF00076.22 RLN69427.1 - 0.00016 21.4 0.0 0.00032 20.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_3 PF15663.5 RLN69427.1 - 0.0091 16.2 0.9 3.4 7.9 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger containing family zf_CCCH_4 PF18345.1 RLN69427.1 - 0.01 15.8 2.3 0.01 15.8 2.3 2.9 3 0 0 3 3 3 0 Zinc finger domain ANAPC4_WD40 PF12894.7 RLN69428.1 - 1.3e-05 25.4 0.2 8.9 6.7 0.0 4.8 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 RLN69428.1 - 0.039 13.0 0.2 0.12 11.5 0.0 1.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) Hira PF07569.11 RLN69428.1 - 0.04 13.6 0.7 8 6.1 0.0 3.5 2 1 2 4 4 4 0 TUP1-like enhancer of split WD40 PF00400.32 RLN69428.1 - 0.14 13.1 5.9 19 6.4 0.1 4.8 5 0 0 5 5 5 0 WD domain, G-beta repeat IQ PF00612.27 RLN69429.1 - 3.3e-15 54.4 48.7 0.0012 18.4 0.1 8.6 8 0 0 8 8 8 6 IQ calmodulin-binding motif LRR_6 PF13516.6 RLN69429.1 - 4.6e-13 48.1 9.8 0.014 15.3 0.0 7.5 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 RLN69429.1 - 0.00013 22.2 1.1 34 5.0 0.1 5.3 1 1 7 8 8 8 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN69429.1 - 3.2 8.6 8.9 50 5.0 0.0 5.9 6 1 1 7 7 7 0 Leucine Rich Repeat Spt5-NGN PF03439.13 RLN69430.1 - 1.1e-19 70.1 0.0 3.9e-19 68.3 0.0 2.0 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 RLN69430.1 - 5.2e-16 58.0 43.0 0.00015 21.6 2.4 8.8 9 0 0 9 9 9 6 KOW motif Spt5_N PF11942.8 RLN69430.1 - 2.6e-11 44.4 17.7 2.6e-11 44.4 17.7 2.7 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal DUF3912 PF13051.6 RLN69430.1 - 0.011 16.0 4.2 0.19 12.0 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3912) Pox_Ag35 PF03286.14 RLN69430.1 - 4.6 7.0 22.3 8.7 6.1 22.3 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Mito_carr PF00153.27 RLN69528.1 - 4.8e-49 164.3 4.4 4.4e-22 77.8 0.0 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein ECH_1 PF00378.20 RLN69529.1 - 7.4e-47 159.8 0.1 1.7e-46 158.6 0.1 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RLN69529.1 - 6.3e-27 94.9 0.1 7e-24 84.9 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase APO_RNA-bind PF05634.11 RLN69529.1 - 0.089 12.2 0.1 0.29 10.5 0.1 1.7 2 0 0 2 2 2 0 APO RNA-binding RmuC PF02646.16 RLN69530.1 - 0.041 13.0 3.1 0.059 12.5 0.0 2.6 3 0 0 3 3 3 0 RmuC family WH2 PF02205.20 RLN69530.1 - 0.14 12.0 14.4 5 7.1 0.2 5.0 5 0 0 5 5 5 0 WH2 motif LCM PF04072.14 RLN69531.1 - 8.6e-40 136.7 0.0 1.1e-39 136.3 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Peptidase_C1 PF00112.23 RLN69532.1 - 1.1e-42 146.6 0.7 1.4e-42 146.2 0.7 1.2 1 0 0 1 1 1 1 Papain family cysteine protease UPF0179 PF03684.13 RLN69532.1 - 0.048 13.6 0.7 0.082 12.8 0.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0179) Peptidase_C1_2 PF03051.15 RLN69532.1 - 0.077 11.8 0.5 1.4 7.6 0.1 2.0 2 0 0 2 2 2 0 Peptidase C1-like family PCMT PF01135.19 RLN69533.1 - 2e-38 132.3 0.0 2.7e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 RLN69533.1 - 2.4e-10 40.4 0.0 4.2e-10 39.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN69533.1 - 1.9e-08 34.9 0.0 4.2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN69533.1 - 6.6e-07 29.9 0.0 1.4e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RLN69533.1 - 1.5e-06 27.8 0.0 2.3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Drc1-Sld2 PF11719.8 RLN69533.1 - 2.1e-06 27.6 0.1 8e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 DNA replication and checkpoint protein Methyltransf_23 PF13489.6 RLN69533.1 - 3.5e-05 23.7 0.0 7.3e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN69533.1 - 0.00016 21.2 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 RLN69533.1 - 0.00039 19.8 0.0 0.00058 19.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 RLN69533.1 - 0.00042 21.0 0.0 0.001 19.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 RLN69533.1 - 0.0036 16.6 0.0 0.0059 15.9 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase GCD14 PF08704.10 RLN69533.1 - 0.022 14.5 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit AviRa PF11599.8 RLN69533.1 - 0.096 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_32 PF13679.6 RLN69533.1 - 0.11 12.5 0.1 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain DIOX_N PF14226.6 RLN69534.1 - 7e-21 75.2 0.0 2.6e-20 73.3 0.0 2.0 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 RLN69534.1 - 0.00018 21.9 0.2 0.00076 19.9 0.2 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2401 PF10287.9 RLN69544.1 - 6.7e-60 202.5 0.7 1.2e-59 201.7 0.7 1.4 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 RLN69544.1 - 1e-10 41.8 0.1 1.1e-09 38.6 0.0 2.9 2 1 2 4 4 4 1 Glycine-rich protein domain (DUF2403) Peptidase_M20 PF01546.28 RLN69545.1 - 1.8e-19 70.2 2.9 8.2e-18 64.9 0.3 2.6 3 0 0 3 3 3 2 Peptidase family M20/M25/M40 M20_dimer PF07687.14 RLN69545.1 - 3e-10 40.0 0.0 7.9e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF4876 PF16215.5 RLN69546.1 - 0.083 12.9 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4876) Ndc80_HEC PF03801.13 RLN69557.1 - 4.7e-21 75.0 0.0 1.3e-20 73.5 0.0 1.8 1 0 0 1 1 1 1 HEC/Ndc80p family PseudoU_synth_2 PF00849.22 RLN69557.1 - 0.037 14.1 0.3 0.069 13.2 0.3 1.5 1 1 0 1 1 1 0 RNA pseudouridylate synthase GNAT_acetyltran PF12746.7 RLN69557.1 - 0.24 10.9 3.8 0.16 11.6 0.3 2.1 1 1 0 2 2 2 0 GNAT acetyltransferase GLYCAM-1 PF05242.11 RLN69558.1 - 0.099 12.8 0.1 0.1 12.7 0.1 1.0 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Ank_2 PF12796.7 RLN69639.1 - 4.7e-84 277.1 10.6 4.7e-21 75.2 0.2 6.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN69639.1 - 7.7e-67 220.5 20.6 4.1e-08 33.3 0.1 11.8 3 2 9 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN69639.1 - 2.1e-66 211.9 0.5 2.7e-06 27.3 0.0 12.3 12 0 0 12 12 12 10 Ankyrin repeat Ank PF00023.30 RLN69639.1 - 1.7e-65 214.8 12.9 4e-06 27.0 0.1 11.8 12 0 0 12 12 12 10 Ankyrin repeat Ank_4 PF13637.6 RLN69639.1 - 6.4e-54 179.7 3.6 5.8e-08 33.1 0.0 9.0 5 2 6 11 11 11 11 Ankyrin repeats (many copies) MMR_HSR1 PF01926.23 RLN69639.1 - 0.00053 20.1 2.1 0.16 12.1 0.1 3.6 3 1 0 3 3 3 2 50S ribosome-binding GTPase DUF3368 PF11848.8 RLN69639.1 - 0.0029 17.4 0.7 20 5.1 0.1 5.6 7 0 0 7 7 7 1 Domain of unknown function (DUF3368) DUF664 PF04978.12 RLN69639.1 - 0.14 12.6 3.0 14 6.1 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF664) DUF4355 PF14265.6 RLN69639.1 - 0.19 12.0 7.3 9.8 6.4 0.1 5.2 3 2 5 8 8 8 0 Domain of unknown function (DUF4355) DDRGK PF09756.9 RLN69640.1 - 0.076 12.6 0.9 0.11 12.0 0.4 1.5 2 0 0 2 2 2 0 DDRGK domain DUF2730 PF10805.8 RLN69640.1 - 0.28 11.3 5.9 6.8 6.9 1.3 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) ThiF PF00899.21 RLN69668.1 - 4.7e-95 317.6 0.0 1.7e-59 201.1 0.0 2.1 2 0 0 2 2 2 2 ThiF family E1_4HB PF16191.5 RLN69668.1 - 3e-23 81.8 0.1 5.8e-23 80.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_FCCH PF16190.5 RLN69668.1 - 7.5e-22 77.3 0.0 1.9e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain UBA_e1_thiolCys PF10585.9 RLN69668.1 - 0.0015 18.5 0.2 0.0031 17.5 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.20 RLN69668.1 - 0.019 15.0 1.0 0.64 10.1 0.1 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF4666 PF15697.5 RLN69669.1 - 0.068 13.9 2.0 0.26 12.0 2.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4666) ACPS PF01648.20 RLN69669.1 - 0.14 12.3 0.5 0.38 10.9 0.5 1.8 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily RTX PF02382.15 RLN69669.1 - 0.24 11.0 1.4 0.38 10.4 1.4 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein PX PF00787.24 RLN69670.1 - 1.5e-16 60.3 0.0 6.2e-16 58.4 0.0 1.8 2 0 0 2 2 2 1 PX domain MAM33 PF02330.16 RLN69678.1 - 4.1e-41 141.3 8.4 4.7e-41 141.1 8.4 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein Cwf_Cwc_15 PF04889.12 RLN69678.1 - 0.027 14.2 8.8 0.04 13.7 8.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GEN1_C PF18380.1 RLN69678.1 - 0.085 13.8 2.9 0.17 12.8 2.9 1.4 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain Prothymosin PF03247.14 RLN69678.1 - 0.42 11.1 17.3 0.37 11.3 15.5 1.8 2 0 0 2 2 2 0 Prothymosin/parathymosin family SDA1 PF05285.12 RLN69678.1 - 0.45 9.9 7.9 0.5 9.8 7.9 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RLN69678.1 - 0.47 8.6 10.2 0.5 8.5 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RLN69678.1 - 0.67 8.2 6.9 0.77 8.0 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 RLN69678.1 - 1.3 8.3 15.2 2 7.7 15.2 1.2 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 RLN69678.1 - 1.6 8.3 10.5 2 7.9 10.5 1.1 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.13 RLN69678.1 - 4.8 5.2 17.5 7.4 4.5 17.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi Methyltransf_16 PF10294.9 RLN69679.1 - 1.9e-17 63.6 0.0 2.6e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 RLN69679.1 - 0.069 13.0 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 RLN69679.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain GidB PF02527.15 RLN69679.1 - 0.16 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G EF-hand_6 PF13405.6 RLN69680.1 - 0.075 13.0 0.1 0.34 10.9 0.1 2.2 1 0 0 1 1 1 0 EF-hand domain DegS PF05384.11 RLN69680.1 - 0.11 12.0 0.4 0.71 9.4 0.0 2.3 2 0 0 2 2 2 0 Sensor protein DegS SARS_3b PF12383.8 RLN69680.1 - 0.15 12.2 0.7 0.33 11.1 0.7 1.5 1 0 0 1 1 1 0 Severe acute respiratory syndrome coronavirus 3b protein TPR_1 PF00515.28 RLN69681.1 - 1.2e-17 62.9 0.3 1.2e-05 24.9 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN69681.1 - 5e-16 57.4 1.5 0.00048 20.0 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat STI1 PF17830.1 RLN69681.1 - 1.5e-13 50.5 24.9 1.5e-09 37.7 1.9 3.6 3 0 0 3 3 3 2 STI1 domain TPR_11 PF13414.6 RLN69681.1 - 1.4e-10 40.7 0.4 0.0033 17.1 0.2 3.5 1 1 2 3 3 3 3 TPR repeat TPR_14 PF13428.6 RLN69681.1 - 5.5e-10 39.2 5.6 0.03 15.1 0.9 4.9 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN69681.1 - 8.8e-09 34.8 1.1 0.1 12.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 RLN69681.1 - 3e-07 31.0 8.9 8.3e-05 23.1 2.4 2.8 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN69681.1 - 3.8e-07 30.5 1.3 0.015 15.8 0.0 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN69681.1 - 4.8e-07 30.0 1.2 0.00011 22.5 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN69681.1 - 4.9e-07 29.4 0.6 0.062 13.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat SGT1 PF07093.11 RLN69681.1 - 0.0001 20.9 0.0 0.00016 20.3 0.0 1.2 1 0 0 1 1 1 1 SGT1 protein XPC-binding PF09280.11 RLN69681.1 - 0.0045 16.7 12.8 0.02 14.6 5.0 3.1 2 1 1 3 3 3 2 XPC-binding domain TPR_9 PF13371.6 RLN69681.1 - 0.0072 16.5 1.4 4.4 7.5 0.3 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat GerD PF17898.1 RLN69681.1 - 0.0093 15.9 5.7 0.0093 15.9 5.7 2.2 3 0 0 3 3 3 1 Spore germination GerD central core domain TPR_10 PF13374.6 RLN69681.1 - 0.011 15.6 7.1 5.1 7.1 0.6 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat VSG_B PF13206.6 RLN69681.1 - 0.05 12.8 1.0 0.073 12.3 1.0 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain TPR_17 PF13431.6 RLN69681.1 - 0.13 12.7 0.1 16 6.2 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat Pkinase PF00069.25 RLN69687.1 - 4.4e-64 216.4 0.0 4.9e-63 213.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN69687.1 - 2.4e-27 95.8 0.0 2.7e-21 76.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RLN69687.1 - 2.1e-10 40.4 0.0 0.0012 18.2 0.0 3.1 2 1 0 3 3 3 2 Kinase-like APH PF01636.23 RLN69687.1 - 0.00078 19.4 1.5 0.08 12.9 0.1 3.0 3 1 1 4 4 4 2 Phosphotransferase enzyme family Kdo PF06293.14 RLN69687.1 - 0.0016 17.8 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN69687.1 - 0.002 17.0 0.0 0.0032 16.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Rad51 PF08423.11 RLN69688.1 - 4.8e-26 91.5 1.3 1e-21 77.4 0.2 2.0 2 0 0 2 2 2 2 Rad51 ATPase PF06745.13 RLN69688.1 - 2e-06 27.3 0.1 0.00019 20.9 0.0 2.1 2 0 0 2 2 2 2 KaiC RecA PF00154.21 RLN69688.1 - 1.9e-05 24.2 0.1 0.0002 20.9 0.0 2.0 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 RLN69688.1 - 0.011 15.3 0.5 0.18 11.4 0.5 2.1 1 1 0 1 1 1 0 AAA domain FmiP_Thoc5 PF09766.9 RLN69689.1 - 4.3e-84 282.9 0.1 6.9e-84 282.2 0.1 1.3 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Baculo_PEP_C PF04513.12 RLN69689.1 - 0.16 12.0 0.1 0.38 10.8 0.1 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 RLN69689.1 - 1.4 9.6 7.2 4.4 8.0 0.5 3.6 3 0 0 3 3 3 0 SlyX KxDL PF10241.9 RLN69690.1 - 0.02 15.2 4.6 0.02 15.2 4.6 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein NACHT_N PF17100.5 RLN69690.1 - 0.024 14.5 0.6 0.028 14.3 0.6 1.1 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase CorA PF01544.18 RLN69690.1 - 0.061 12.6 4.2 0.095 12.0 4.2 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Metal_resist PF13801.6 RLN69690.1 - 0.17 12.0 2.8 0.42 10.8 0.3 2.1 1 1 1 2 2 2 0 Heavy-metal resistance DUF2721 PF11026.8 RLN69690.1 - 0.29 11.0 3.5 0.83 9.5 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) APG6_N PF17675.1 RLN69690.1 - 0.34 11.5 12.2 0.027 15.0 7.1 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4715 PF15835.5 RLN69690.1 - 0.4 10.7 4.2 0.83 9.7 3.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4715) DUF1664 PF07889.12 RLN69690.1 - 0.54 10.3 3.6 0.84 9.7 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 RLN69690.1 - 0.86 9.7 11.0 1.7 8.7 7.5 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 RLN69690.1 - 0.93 8.3 12.8 0.05 12.5 7.5 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein TMCO5 PF14992.6 RLN69690.1 - 1.8 8.1 10.8 0.33 10.5 4.8 2.0 2 0 0 2 2 2 0 TMCO5 family DUF724 PF05266.14 RLN69690.1 - 2.5 7.9 9.4 0.15 11.8 4.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) HAUS6_N PF14661.6 RLN69690.1 - 5.7 6.5 9.4 32 4.0 9.4 2.1 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Nodulin-like PF06813.13 RLN69782.1 - 0.0024 17.4 4.1 0.0033 16.9 4.1 1.2 1 0 0 1 1 1 1 Nodulin-like zf-RING_2 PF13639.6 RLN69783.1 - 2.3e-12 47.0 13.4 2.3e-12 47.0 13.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 RLN69783.1 - 8.6e-11 41.4 6.5 2.6e-10 39.8 6.5 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 RLN69783.1 - 3.8e-06 26.7 9.3 3.8e-06 26.7 9.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN69783.1 - 1.1e-05 25.6 12.2 3.1e-05 24.2 12.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 RLN69783.1 - 3.7e-05 23.5 13.8 3.7e-05 23.5 13.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN69783.1 - 9.5e-05 22.4 6.5 9.5e-05 22.4 6.5 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RLN69783.1 - 0.00016 21.5 9.1 0.00016 21.5 9.1 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN69783.1 - 0.00075 19.3 8.0 0.0016 18.2 8.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN69783.1 - 0.0044 17.0 11.1 0.0044 17.0 11.1 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 RLN69783.1 - 0.033 14.2 7.1 0.11 12.5 7.1 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 RLN69783.1 - 4.3 7.6 10.1 17 5.7 10.1 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain PDZ PF00595.24 RLN69784.1 - 0.0065 16.8 0.0 1.3 9.4 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Tmemb_14 PF03647.13 RLN69797.1 - 2.1e-32 111.7 25.1 2.2e-20 73.2 9.8 2.1 2 0 0 2 2 2 2 Transmembrane proteins 14C Aim19 PF10315.9 RLN69797.1 - 9.3e-05 22.7 0.4 9.3e-05 22.7 0.4 1.9 2 0 0 2 2 2 1 Altered inheritance of mitochondria protein 19 DUF1449 PF07290.11 RLN69797.1 - 0.023 14.4 0.0 0.054 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) MgtC PF02308.16 RLN69797.1 - 0.027 14.8 14.5 0.61 10.5 8.1 3.0 1 1 1 2 2 2 0 MgtC family PFK PF00365.20 RLN69798.1 - 2.6e-60 204.2 0.2 3.4e-60 203.8 0.2 1.1 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 RLN69798.1 - 0.0023 17.6 0.0 0.0062 16.1 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 RLN69798.1 - 0.06 12.5 0.0 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 ATP-NAD kinase Aminotran_1_2 PF00155.21 RLN69799.1 - 8e-39 133.8 0.0 1e-38 133.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 RLN69799.1 - 0.028 13.7 0.0 0.064 12.5 0.0 1.6 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_MocR PF12897.7 RLN69799.1 - 0.028 13.2 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase His_Phos_2 PF00328.22 RLN69800.1 - 1.9e-08 34.1 0.2 0.00011 21.7 0.0 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) tRNA_SAD PF07973.14 RLN69801.1 - 2.3e-06 27.6 0.0 6.5e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 RLN69801.1 - 0.0043 15.6 0.0 0.0062 15.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) Matrilin_ccoil PF10393.9 RLN69801.1 - 4 7.4 6.2 3 7.8 1.1 2.5 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin WD40 PF00400.32 RLN69803.1 - 1.3e-11 44.8 13.3 0.093 13.6 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat Sec16_C PF12931.7 RLN69803.1 - 5.5e-09 36.1 0.4 5e-08 32.9 0.4 2.1 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 ANAPC4_WD40 PF12894.7 RLN69803.1 - 1.9e-06 28.1 0.0 0.14 12.5 0.1 3.7 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Prp18 PF02840.15 RLN69803.1 - 0.18 11.8 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Prp18 domain SRA1 PF07304.11 RLN69803.1 - 0.36 10.6 1.8 2 8.2 0.0 2.7 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) SUIM_assoc PF16619.5 RLN69803.1 - 0.65 10.1 11.8 0.029 14.4 5.3 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 BBS2_C PF14782.6 RLN69804.1 - 1.1e-140 469.2 0.0 2.9e-138 461.3 0.0 2.7 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 RLN69804.1 - 8.1e-43 144.9 0.0 4.9e-40 135.9 0.0 2.8 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 RLN69804.1 - 6.6e-38 128.8 0.0 3.4e-37 126.5 0.0 2.3 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, N-terminal Itfg2 PF15907.5 RLN69804.1 - 7.8e-07 28.4 0.0 0.71 8.8 0.0 3.4 2 1 1 3 3 3 3 Integrin-alpha FG-GAP repeat-containing protein 2 VCBS PF13517.6 RLN69804.1 - 0.0015 19.1 0.0 0.91 10.2 0.1 3.6 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella HEAT PF02985.22 RLN69805.1 - 1.5e-05 24.8 0.7 19 5.9 0.0 5.2 4 0 0 4 4 4 3 HEAT repeat Kinase-PolyVal PF18762.1 RLN69805.1 - 0.0029 17.6 0.1 0.0065 16.4 0.1 1.5 1 0 0 1 1 1 1 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins His_Phos_2 PF00328.22 RLN69806.1 - 2.1e-82 277.5 1.2 8e-79 265.7 0.1 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 RLN69806.1 - 6.7e-38 128.7 0.0 1.8e-37 127.3 0.0 1.8 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 RLN69806.1 - 0.0011 18.6 0.0 0.018 14.7 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Mto2_bdg PF12808.7 RLN69806.1 - 0.15 12.4 0.5 0.55 10.6 0.5 1.9 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region PIN_8 PF18476.1 RLN69811.1 - 2.6 7.8 5.1 1.8 8.4 1.4 2.0 1 1 1 2 2 2 0 PIN like domain Ank_2 PF12796.7 RLN69812.1 - 3.6e-90 296.7 7.7 1.2e-13 51.4 0.0 7.0 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN69812.1 - 6.3e-70 230.7 7.1 3.2e-09 37.1 0.0 10.1 2 2 8 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN69812.1 - 3.4e-67 221.6 11.6 1.5e-07 31.5 0.1 12.1 1 1 12 13 13 13 13 Ankyrin repeats (many copies) Ank PF00023.30 RLN69812.1 - 3.7e-61 201.0 16.6 3.5e-05 24.0 0.0 13.2 13 0 0 13 13 13 13 Ankyrin repeat Ank_3 PF13606.6 RLN69812.1 - 9.5e-58 185.4 0.8 0.0055 17.1 0.0 13.4 14 0 0 14 14 14 13 Ankyrin repeat DUF1949 PF09186.11 RLN69812.1 - 1.6e-06 27.9 2.7 2.1 8.3 0.0 5.9 7 0 0 7 7 7 2 Domain of unknown function (DUF1949) Imm_superinfect PF14373.6 RLN69812.1 - 0.00045 20.1 0.0 7 6.7 0.0 5.1 6 0 0 6 6 6 1 Superinfection immunity protein OAM_dimer PF16554.5 RLN69812.1 - 0.009 16.4 6.5 13 6.3 0.0 5.6 6 0 0 6 6 6 1 Dimerisation domain of d-ornithine 4,5-aminomutase SIP PF04954.13 RLN69812.1 - 0.013 16.0 0.0 6.1 7.4 0.0 3.5 3 1 0 3 3 3 0 Siderophore-interacting protein SNARE_assoc PF09335.11 RLN69813.1 - 2.2e-16 60.4 5.5 2.2e-16 60.4 5.5 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein RabGAP-TBC PF00566.18 RLN69815.1 - 6.5e-59 199.2 0.1 8.6e-59 198.8 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain OST3_OST6 PF04756.13 RLN69841.1 - 0.23 10.8 2.0 1.2 8.4 0.3 2.4 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Ank_2 PF12796.7 RLN69842.1 - 3.3e-06 27.6 0.0 0.067 13.8 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN69842.1 - 6.4e-05 23.1 0.1 13 6.7 0.0 5.2 6 1 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 RLN69842.1 - 0.0013 18.9 0.4 16 6.0 0.0 4.8 3 1 2 5 5 5 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN69842.1 - 0.0018 18.8 0.3 4.5 8.0 0.0 3.8 3 1 0 3 3 3 2 Ankyrin repeats (many copies) DUF249 PF03158.13 RLN69842.1 - 0.089 12.5 0.0 0.24 11.1 0.0 1.6 2 0 0 2 2 2 0 Multigene family 530 protein PUF PF00806.19 RLN69842.1 - 0.2 11.4 0.1 2.6 7.9 0.1 2.5 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat Ribosomal_L5_C PF00673.21 RLN69844.1 - 2.6e-21 75.6 0.0 4e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 RLN69844.1 - 3.2e-21 75.4 0.0 4.9e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 Helicase_C_2 PF13307.6 RLN69845.1 - 4.9e-17 62.6 0.0 6.2e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Helicase C-terminal domain CSG2 PF16965.5 RLN69850.1 - 0.011 14.7 0.3 0.014 14.4 0.3 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Serglycin PF04360.12 RLN69850.1 - 0.076 13.0 1.3 0.16 12.0 1.3 1.5 1 0 0 1 1 1 0 Serglycin DUF1180 PF06679.12 RLN69850.1 - 0.13 12.7 2.2 0.23 11.8 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) Sugar_tr PF00083.24 RLN69851.1 - 2.6e-100 336.4 25.3 3.1e-100 336.2 25.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN69851.1 - 1.1e-22 80.5 37.8 7.8e-15 54.6 13.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RLN69851.1 - 0.0033 16.1 2.1 0.0033 16.1 2.1 4.1 2 2 2 4 4 4 2 MFS/sugar transport protein AOX PF01786.17 RLN69855.1 - 2.1e-92 308.6 0.0 2.6e-92 308.3 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase SlyX PF04102.12 RLN69880.1 - 0.03 14.9 0.9 0.084 13.5 0.4 1.9 2 0 0 2 2 2 0 SlyX DUF745 PF05335.13 RLN69880.1 - 0.056 13.2 1.5 0.19 11.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF848 PF05852.11 RLN69880.1 - 0.13 12.3 2.9 0.31 11.1 0.6 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) NPV_P10 PF05531.12 RLN69880.1 - 0.14 12.7 1.3 5.2 7.6 0.5 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ATP_bind_3 PF01171.20 RLN69881.1 - 4.5e-45 153.6 0.0 3e-44 151.0 0.0 1.9 1 1 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 RLN69881.1 - 0.0026 17.5 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.16 RLN69881.1 - 0.059 12.2 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase PAPS_reduct PF01507.19 RLN69881.1 - 0.086 12.9 0.0 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family PCI PF01399.27 RLN69882.1 - 7e-18 65.1 0.5 1.6e-17 64.0 0.5 1.6 1 0 0 1 1 1 1 PCI domain Glutaredoxin PF00462.24 RLN69883.1 - 6.8e-17 61.5 1.6 3.7e-13 49.5 0.0 2.8 3 0 0 3 3 3 2 Glutaredoxin Pro_isomerase PF00160.21 RLN69883.1 - 7.7e-17 62.0 0.1 1.2e-16 61.3 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_2 PF13098.6 RLN69883.1 - 0.0018 18.7 0.0 0.046 14.2 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain DUF836 PF05768.14 RLN69883.1 - 0.0032 17.8 0.0 0.0064 16.9 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_2 PF13409.6 RLN69883.1 - 0.037 14.3 0.0 0.31 11.4 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Aldo_ket_red PF00248.21 RLN69884.1 - 3.1e-50 171.1 0.3 2.2e-25 89.5 0.0 2.8 2 1 0 3 3 3 2 Aldo/keto reductase family Pkinase_Tyr PF07714.17 RLN69885.1 - 2.1e-58 197.7 0.0 5.6e-44 150.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN69885.1 - 5.2e-51 173.5 0.0 6.1e-38 130.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Arm PF00514.23 RLN69885.1 - 1.5e-11 43.9 2.2 0.11 12.6 0.0 6.9 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN69885.1 - 0.00096 19.6 9.2 0.044 14.3 0.3 4.9 5 0 0 5 5 5 1 HEAT-like repeat MoaE PF02391.17 RLN69885.1 - 0.0029 17.9 0.0 25 5.2 0.0 4.2 3 1 1 4 4 4 0 MoaE protein HEAT_2 PF13646.6 RLN69885.1 - 0.055 13.9 18.3 0.35 11.3 3.1 4.9 4 2 2 6 6 6 0 HEAT repeats Kinase-like PF14531.6 RLN69885.1 - 0.094 12.0 0.0 4 6.7 0.0 2.4 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 RLN69885.1 - 0.097 11.4 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinesin PF00225.23 RLN70013.1 - 2.4e-95 319.3 0.1 3.8e-95 318.6 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN70013.1 - 1e-20 74.2 0.0 2.9e-20 72.7 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding DUF4407 PF14362.6 RLN70013.1 - 0.3 10.4 9.4 0.11 11.9 5.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Cnn_1N PF07989.11 RLN70013.1 - 4.5 7.5 11.3 0.14 12.3 1.1 3.2 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 BolA PF01722.18 RLN70014.1 - 5.8e-10 39.3 0.0 1.1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 BolA-like protein Fer4_22 PF17179.4 RLN70014.1 - 0.099 13.5 0.0 3.4 8.6 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain CNDH2_C PF16858.5 RLN70017.1 - 2.7e-80 270.4 0.4 2.7e-80 270.4 0.4 2.7 3 1 0 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 RLN70017.1 - 1.1e-34 119.0 1.0 1.1e-34 119.0 1.0 2.6 2 1 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Rad21_Rec8_N PF04825.13 RLN70017.1 - 0.12 12.5 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein Cnd2 PF05786.14 RLN70017.1 - 8.3 4.9 30.2 0.046 12.4 6.9 3.9 3 1 0 3 3 3 0 Condensin complex subunit 2 MMR_HSR1 PF01926.23 RLN70018.1 - 1.6e-09 37.8 0.0 3.3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 RLN70018.1 - 3.7e-07 29.7 0.0 6.4e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 RLN70018.1 - 0.0004 20.3 0.1 0.0018 18.2 0.1 2.1 2 1 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 RLN70018.1 - 0.0021 18.5 0.1 0.0082 16.5 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 RLN70018.1 - 0.0027 18.2 0.0 0.0084 16.6 0.0 1.8 2 1 0 2 2 2 1 ABC transporter Dynamin_N PF00350.23 RLN70018.1 - 0.0033 17.5 0.7 0.47 10.5 0.2 2.8 3 0 0 3 3 3 1 Dynamin family AAA_28 PF13521.6 RLN70018.1 - 0.0046 17.2 0.5 1.3 9.2 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 RLN70018.1 - 0.0069 16.9 0.0 0.02 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RLN70018.1 - 0.013 16.0 0.0 0.034 14.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 RLN70018.1 - 0.018 15.5 0.0 0.064 13.7 0.0 1.8 1 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 RLN70018.1 - 0.02 15.2 0.0 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 RLN70018.1 - 0.023 15.2 0.5 2.4 8.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 RLN70018.1 - 0.025 14.3 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain BMFP PF04380.13 RLN70018.1 - 0.043 14.3 4.6 7 7.2 2.7 2.7 2 1 1 3 3 2 0 Membrane fusogenic activity RNA_helicase PF00910.22 RLN70018.1 - 0.05 14.0 0.4 0.6 10.5 0.1 2.7 1 1 1 2 2 2 0 RNA helicase betaPIX_CC PF16523.5 RLN70018.1 - 0.056 13.3 0.2 0.34 10.7 0.3 2.1 2 0 0 2 2 2 0 betaPIX coiled coil SRPRB PF09439.10 RLN70018.1 - 0.069 12.6 0.0 0.18 11.2 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DivIC PF04977.15 RLN70018.1 - 0.069 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 Septum formation initiator Flavodoxin_NdrI PF07972.11 RLN70018.1 - 0.079 13.1 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 NrdI Flavodoxin like AAA_24 PF13479.6 RLN70018.1 - 0.086 12.6 0.1 4.6 6.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain Septin PF00735.18 RLN70018.1 - 0.09 12.0 0.1 0.45 9.7 0.0 2.1 1 1 0 2 2 2 0 Septin FeoB_N PF02421.18 RLN70018.1 - 0.095 12.2 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_19 PF13245.6 RLN70018.1 - 0.097 13.0 0.1 0.19 12.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 RLN70018.1 - 0.11 12.0 0.7 11 5.5 0.0 2.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain FlaC_arch PF05377.11 RLN70018.1 - 0.11 12.9 1.3 0.23 11.9 0.1 2.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) MutS_IV PF05190.18 RLN70018.1 - 0.23 11.8 1.2 16 5.9 0.2 2.4 2 0 0 2 2 2 0 MutS family domain IV MMR_HSR1 PF01926.23 RLN70019.1 - 1e-10 41.7 0.1 2.3e-09 37.3 0.0 2.4 2 1 0 3 3 3 1 50S ribosome-binding GTPase AIG1 PF04548.16 RLN70019.1 - 3e-07 30.0 0.0 4.1e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 RLN70019.1 - 0.00026 20.9 0.1 0.0011 18.9 0.1 2.1 1 1 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 RLN70019.1 - 0.00069 20.0 0.0 0.0025 18.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 RLN70019.1 - 0.0012 19.3 0.2 0.017 15.6 0.0 2.5 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 RLN70019.1 - 0.0013 18.2 0.0 0.082 12.3 0.0 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 RLN70019.1 - 0.0015 18.6 1.3 0.42 10.7 0.2 2.8 2 1 1 3 3 3 1 Dynamin family ABC_tran PF00005.27 RLN70019.1 - 0.002 18.7 0.0 0.004 17.7 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 RLN70019.1 - 0.0033 18.0 0.0 0.01 16.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RLN70019.1 - 0.0057 16.9 0.0 0.1 12.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 RLN70019.1 - 0.0099 15.6 0.1 5 6.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 RLN70019.1 - 0.011 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 RLN70019.1 - 0.013 15.8 0.8 1.2 9.4 0.1 2.6 2 1 1 3 3 2 0 AAA domain AAA_17 PF13207.6 RLN70019.1 - 0.016 15.7 0.1 0.033 14.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 RLN70019.1 - 0.016 15.0 1.1 0.53 10.0 0.2 2.4 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein NRBF2 PF08961.10 RLN70019.1 - 0.024 14.3 0.1 0.041 13.5 0.1 1.3 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator RNA_helicase PF00910.22 RLN70019.1 - 0.04 14.3 0.3 0.37 11.2 0.1 2.6 1 1 1 2 2 2 0 RNA helicase ZapB PF06005.12 RLN70019.1 - 0.048 14.1 0.2 0.1 13.0 0.2 1.5 1 0 0 1 1 1 0 Cell division protein ZapB Septin PF00735.18 RLN70019.1 - 0.05 12.9 0.1 0.31 10.3 0.0 2.3 1 1 0 2 2 2 0 Septin FeoB_N PF02421.18 RLN70019.1 - 0.064 12.8 0.0 0.18 11.3 0.0 1.9 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF2353 PF09789.9 RLN70019.1 - 0.072 12.4 0.2 0.096 12.0 0.2 1.3 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) AAA_19 PF13245.6 RLN70019.1 - 0.12 12.7 0.0 0.14 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 RLN70019.1 - 0.14 12.7 0.0 2.1 8.8 0.1 2.1 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 RLN70019.1 - 0.24 10.9 0.8 12 5.4 0.0 3.0 2 2 1 3 3 3 0 Elongation factor Tu GTP binding domain Retinal PF15449.6 RLN70032.1 - 0.00079 17.4 1.0 0.0012 16.8 1.0 1.2 1 0 0 1 1 1 1 Retinal protein FYVE_2 PF02318.16 RLN70032.1 - 0.017 15.3 9.2 0.049 13.8 9.2 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger ABC2_membrane PF01061.24 RLN70035.1 - 1.4e-29 103.0 32.4 1.4e-29 103.0 32.4 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RLN70035.1 - 3.2e-10 40.7 0.0 5e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN70035.1 - 0.0094 15.8 0.0 0.045 13.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system PDR_CDR PF06422.12 RLN70035.1 - 0.013 15.4 2.5 0.022 14.6 0.0 2.4 2 0 0 2 2 2 0 CDR ABC transporter DDOST_48kD PF03345.14 RLN70036.1 - 5.5e-119 397.7 0.0 6.3e-119 397.5 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Sugar_tr PF00083.24 RLN70058.1 - 2.3e-40 138.8 20.6 3.5e-40 138.2 20.6 1.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN70058.1 - 1.4e-21 76.8 39.5 1.3e-15 57.3 20.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 RLN70058.1 - 0.00036 19.9 2.3 0.00036 19.9 2.3 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Na_Pi_cotrans PF02690.15 RLN70059.1 - 2.3e-38 131.4 26.9 1.1e-20 74.1 6.8 2.7 2 1 0 2 2 2 2 Na+/Pi-cotransporter C2 PF00168.30 RLN70062.1 - 0.041 14.2 0.0 0.064 13.6 0.0 1.4 1 1 0 1 1 1 0 C2 domain GATase_2 PF00310.21 RLN70064.1 - 2.7e-54 184.5 0.0 3.1e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PLAC8 PF04749.17 RLN70065.1 - 1.2e-11 45.5 0.2 1.5e-11 45.2 0.2 1.1 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 RLN70066.1 - 8.2e-11 42.8 3.1 1.1e-10 42.4 3.1 1.2 1 0 0 1 1 1 1 PLAC8 family UAA PF08449.11 RLN70066.1 - 0.14 11.3 4.7 0.094 11.9 3.5 1.3 1 1 0 1 1 1 0 UAA transporter family SLATT_3 PF18184.1 RLN70066.1 - 0.65 10.1 2.1 1 9.5 2.1 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 HSF_DNA-bind PF00447.17 RLN70067.1 - 9.8e-25 87.0 4.5 1.8e-24 86.1 4.5 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding WD40 PF00400.32 RLN70068.1 - 1.3e-23 82.8 19.0 3.1e-05 24.7 0.3 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 RLN70068.1 - 4.2e-08 32.5 0.5 0.011 14.7 0.1 3.7 2 2 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 RLN70068.1 - 3.3e-06 27.3 0.1 4.4 7.7 0.0 5.3 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN70068.1 - 0.011 14.4 0.5 0.44 9.1 0.2 3.0 2 2 2 4 4 4 0 Nucleoporin Nup120/160 COX6B PF02297.17 RLN70069.1 - 6.8e-16 58.3 6.0 7.8e-16 58.1 6.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.13 RLN70069.1 - 0.012 15.7 2.4 0.02 15.0 1.2 2.0 2 1 0 2 2 2 0 CHCH domain TGT PF01702.18 RLN70070.1 - 8.6e-135 449.4 0.0 1.2e-134 448.9 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Aminotran_3 PF00202.21 RLN70072.1 - 2.2e-104 349.4 0.0 2e-101 339.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-III Aminotran_1_2 PF00155.21 RLN70072.1 - 1.6e-05 24.2 0.0 2e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 RLN70072.1 - 0.044 12.7 0.0 0.076 12.0 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.21 RLN70072.1 - 0.15 11.3 0.0 0.71 9.1 0.0 1.9 1 1 0 1 1 1 0 Beta-eliminating lyase Macro PF01661.21 RLN70073.1 - 3e-13 49.8 0.0 4.7e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Macro domain LRR_4 PF12799.7 RLN70076.1 - 1.9e-07 31.3 16.7 0.00055 20.3 0.0 6.4 2 2 5 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN70076.1 - 4.4e-05 23.2 16.3 0.65 9.8 0.0 5.7 3 1 3 6 6 6 4 Leucine rich repeat LRR_6 PF13516.6 RLN70076.1 - 0.00049 19.9 5.1 30 5.0 0.0 6.5 6 2 1 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 RLN70076.1 - 1.5 9.7 20.0 20 6.3 1.4 7.4 6 3 0 6 6 6 0 Leucine Rich Repeat TPR_2 PF07719.17 RLN70077.1 - 4.3e-06 26.4 0.3 0.076 13.2 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN70077.1 - 3.8e-05 24.1 0.0 0.068 14.0 0.0 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN70077.1 - 6.1e-05 23.4 0.0 0.00014 22.3 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN70077.1 - 0.00047 20.1 0.5 1.5 9.3 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN70077.1 - 0.0011 18.7 0.0 0.36 10.7 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN70077.1 - 0.0096 16.1 0.8 0.02 15.1 0.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 RLN70077.1 - 0.02 15.0 0.0 0.06 13.5 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 RLN70077.1 - 0.028 14.1 0.0 10 5.9 0.0 3.3 3 1 1 4 4 4 0 TPR repeat SHNi-TPR PF10516.9 RLN70077.1 - 0.054 12.9 0.7 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 SHNi-TPR RR_TM4-6 PF06459.12 RLN70077.1 - 5 6.9 9.7 7.6 6.3 9.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ank_5 PF13857.6 RLN70078.1 - 1.6e-19 69.7 1.8 2.3e-10 40.5 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN70078.1 - 7e-15 55.2 0.0 9.9e-14 51.5 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN70078.1 - 3.3e-14 53.2 0.0 4.1e-06 27.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RLN70078.1 - 8.9e-13 48.1 0.3 2.4e-05 24.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 RLN70078.1 - 4.8e-12 45.0 0.0 6.5e-05 23.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat PurS PF02700.14 RLN70080.1 - 0.26 11.5 0.5 0.59 10.4 0.5 1.6 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase DUF3275 PF11679.8 RLN70080.1 - 0.32 11.0 5.0 0.53 10.2 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) zinc_ribbon_6 PF14599.6 RLN70080.1 - 2.4 8.2 10.7 0.17 11.9 5.2 2.0 2 0 0 2 2 2 0 Zinc-ribbon Hap4_Hap_bind PF10297.9 RLN70081.1 - 6.7 7.0 7.8 0.86 9.8 0.9 3.2 3 0 0 3 3 3 0 Minimal binding motif of Hap4 for binding to Hap2/3/5 Sulfate_transp PF00916.20 RLN70082.1 - 7.3e-157 522.0 47.8 2.1e-43 148.5 4.5 4.6 5 0 0 5 5 5 4 Sulfate permease family MscL PF01741.18 RLN70082.1 - 5.4e-40 136.5 0.7 2.3e-20 73.1 0.0 3.7 3 0 0 3 3 3 2 Large-conductance mechanosensitive channel, MscL STAS PF01740.21 RLN70082.1 - 3.4e-24 84.7 0.9 6.6e-13 48.3 0.1 2.6 2 0 0 2 2 2 2 STAS domain STAS_2 PF13466.6 RLN70082.1 - 0.00017 21.9 0.4 0.12 12.8 0.1 3.1 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 RLN70082.1 - 0.002 18.5 4.5 0.002 18.5 4.5 5.2 4 0 0 4 4 4 2 Molybdate transporter of MFS superfamily UPF0547 PF10571.9 RLN70082.1 - 0.0033 17.4 3.8 0.0071 16.4 3.8 1.5 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.6 RLN70082.1 - 0.0039 16.6 1.9 0.0073 15.7 1.9 1.5 1 0 0 1 1 1 1 zinc-ribbon domain CobT PF06213.12 RLN70082.1 - 0.0044 16.4 6.5 0.0044 16.4 6.5 2.2 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT TM_helix PF05552.12 RLN70082.1 - 0.02 14.8 5.0 0.3 11.1 0.4 3.3 2 0 0 2 2 2 0 Conserved TM helix DUF1153 PF06627.11 RLN70082.1 - 0.045 13.9 0.6 11 6.3 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1153) CoA_binding_3 PF13727.6 RLN70082.1 - 0.12 12.3 8.1 0.66 10.0 0.2 3.2 3 0 0 3 3 2 0 CoA-binding domain Zn_ribbon_17 PF17120.5 RLN70082.1 - 0.41 10.3 2.4 0.79 9.4 2.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type WW PF00397.26 RLN70084.1 - 8.6e-07 28.9 4.3 1.7e-06 28.0 4.3 1.5 1 0 0 1 1 1 1 WW domain Peptidase_C9 PF01707.16 RLN70084.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C9 AAA_2 PF07724.14 RLN70085.1 - 8.6e-53 178.9 6.5 6.7e-51 172.8 0.0 3.8 4 0 0 4 4 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 RLN70085.1 - 4.1e-35 119.8 2.7 4.1e-35 119.8 2.7 3.3 3 1 0 3 3 2 1 AAA lid domain AAA PF00004.29 RLN70085.1 - 3.2e-27 95.6 0.6 1.6e-13 51.2 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 RLN70085.1 - 7.7e-21 73.9 1.7 2e-20 72.6 0.2 2.7 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 RLN70085.1 - 2.7e-19 69.5 0.7 6.1e-13 49.0 0.0 3.9 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 RLN70085.1 - 4e-14 52.5 9.4 1.1e-06 28.6 0.0 3.8 4 0 0 4 4 3 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 RLN70085.1 - 7.3e-11 42.7 10.4 1.3e-05 25.6 0.1 5.0 3 3 0 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 RLN70085.1 - 6.7e-10 39.4 5.8 0.0011 19.2 0.0 5.2 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.26 RLN70085.1 - 7.8e-10 38.7 0.0 3.3e-07 30.2 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 RLN70085.1 - 4.6e-08 33.0 0.0 0.0013 18.4 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_14 PF13173.6 RLN70085.1 - 1.2e-07 31.8 0.0 0.024 14.7 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_7 PF12775.7 RLN70085.1 - 9.2e-07 28.5 0.0 0.0093 15.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region TniB PF05621.11 RLN70085.1 - 5.1e-06 26.0 3.2 0.0091 15.4 0.0 4.5 3 1 0 3 3 3 1 Bacterial TniB protein RuvB_N PF05496.12 RLN70085.1 - 9.7e-06 25.4 2.4 0.23 11.2 0.0 4.5 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 RLN70085.1 - 1.4e-05 25.0 0.3 0.0067 16.3 0.0 3.5 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 RLN70085.1 - 2e-05 24.6 11.0 0.43 10.4 0.1 4.9 5 1 1 6 6 4 3 ATPase domain predominantly from Archaea AAA_18 PF13238.6 RLN70085.1 - 3.8e-05 24.2 6.7 0.12 13.0 0.0 4.8 5 1 0 5 5 3 1 AAA domain AAA_25 PF13481.6 RLN70085.1 - 4.6e-05 23.1 0.1 0.021 14.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 RLN70085.1 - 6.9e-05 22.3 0.0 0.65 9.3 0.0 3.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Roc PF08477.13 RLN70085.1 - 0.00013 22.2 0.0 0.36 11.1 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 RLN70085.1 - 0.00027 20.9 0.0 0.58 10.1 0.0 2.9 2 0 0 2 2 2 2 NACHT domain DNA_pol3_delta2 PF13177.6 RLN70085.1 - 0.00044 20.1 0.0 0.015 15.1 0.0 2.9 1 1 0 1 1 1 1 DNA polymerase III, delta subunit RNA_helicase PF00910.22 RLN70085.1 - 0.00049 20.5 0.1 0.81 10.1 0.0 3.1 3 0 0 3 3 2 1 RNA helicase AAA_28 PF13521.6 RLN70085.1 - 0.00051 20.3 10.4 3.6 7.8 0.0 6.0 6 2 0 6 6 5 1 AAA domain RsgA_GTPase PF03193.16 RLN70085.1 - 0.00087 19.2 0.2 2.1 8.2 0.0 3.2 3 0 0 3 3 2 2 RsgA GTPase TsaE PF02367.17 RLN70085.1 - 0.00088 19.3 0.0 2.1 8.4 0.0 3.1 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 RLN70085.1 - 0.00097 18.5 0.4 0.073 12.3 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin AAA_23 PF13476.6 RLN70085.1 - 0.0027 18.2 18.2 0.018 15.5 0.0 3.9 2 1 0 2 2 1 1 AAA domain AAA_24 PF13479.6 RLN70085.1 - 0.0036 17.1 0.2 3.3 7.4 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 RLN70085.1 - 0.0036 17.5 2.2 0.72 10.0 0.0 3.8 4 2 0 4 4 4 1 AAA domain ResIII PF04851.15 RLN70085.1 - 0.0053 16.8 0.0 0.71 9.9 0.0 3.7 4 0 0 4 4 3 1 Type III restriction enzyme, res subunit DUF87 PF01935.17 RLN70085.1 - 0.0066 16.6 6.4 0.34 11.0 0.0 4.1 4 0 0 4 4 4 1 Helicase HerA, central domain ABC_tran PF00005.27 RLN70085.1 - 0.0091 16.5 2.8 0.65 10.5 0.0 3.8 3 1 0 3 3 3 1 ABC transporter AAA_29 PF13555.6 RLN70085.1 - 0.015 15.0 0.0 6 6.7 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain HEPN_Swt1 PF18731.1 RLN70085.1 - 0.074 13.4 3.1 0.34 11.3 2.4 2.5 2 0 0 2 2 2 0 Swt1-like HEPN NTPase_1 PF03266.15 RLN70085.1 - 0.1 12.5 1.7 17 5.3 0.0 4.0 4 0 0 4 4 4 0 NTPase AAA_19 PF13245.6 RLN70085.1 - 0.33 11.3 6.6 1.1 9.6 0.4 4.5 5 1 0 5 5 5 0 AAA domain UvrD-helicase PF00580.21 RLN70085.1 - 1.7 8.1 11.1 0.47 9.9 5.7 2.6 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain ABC_tran_CTD PF16326.5 RLN70085.1 - 7.2 6.9 15.2 0.49 10.7 3.3 3.5 2 1 1 3 3 2 0 ABC transporter C-terminal domain 2OG-FeII_Oxy_3 PF13640.6 RLN70087.1 - 1.7e-10 41.6 0.1 2.4e-10 41.2 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 RLN70087.1 - 1.1e-05 25.8 0.0 1.5e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 RLN70087.1 - 0.0019 18.8 0.0 0.0028 18.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FHA PF00498.26 RLN70088.1 - 4.8e-29 100.5 0.7 3.9e-15 56.0 0.0 2.4 2 0 0 2 2 2 2 FHA domain Yop-YscD_cpl PF16697.5 RLN70088.1 - 4.3e-16 59.0 0.0 4.5e-07 30.1 0.0 2.5 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain RWP-RK PF02042.15 RLN70089.1 - 2.2e-21 75.5 0.3 7.2e-21 73.9 0.1 2.0 2 0 0 2 2 2 1 RWP-RK domain Peptidase_S28 PF05577.12 RLN70090.1 - 1.3e-67 228.5 0.0 1.6e-67 228.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 RLN70090.1 - 9.6e-06 24.5 0.0 1.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 RLN70090.1 - 0.00012 21.4 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN70090.1 - 0.00027 20.7 0.2 0.00066 19.4 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF2920 PF11144.8 RLN70090.1 - 0.0012 18.1 0.1 0.0019 17.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Abhydrolase_6 PF12697.7 RLN70090.1 - 0.025 15.2 7.2 0.65 10.6 7.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 RLN70090.1 - 0.052 13.0 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pkinase PF00069.25 RLN70091.1 - 4.2e-75 252.5 0.0 5.3e-75 252.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN70091.1 - 6.4e-35 120.7 0.0 9.6e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN70091.1 - 1.7e-07 30.9 0.0 3.9e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 RLN70091.1 - 0.00074 19.2 0.1 0.0012 18.5 0.1 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 RLN70091.1 - 0.0036 17.3 0.2 0.2 11.5 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 RLN70091.1 - 0.0048 16.6 0.1 1.5 8.4 0.0 2.4 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 RLN70091.1 - 0.0088 15.0 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RLN70091.1 - 0.11 11.8 0.4 0.24 10.8 0.4 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 RLN70091.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 D5_N PF08706.11 RLN70091.1 - 0.24 11.7 0.3 2.7 8.3 0.3 2.1 1 1 0 1 1 1 0 D5 N terminal like Enolase_C PF00113.22 RLN70092.1 - 1.6e-30 106.4 0.0 2.8e-18 66.2 0.0 2.8 2 1 0 2 2 2 2 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 RLN70092.1 - 1.5e-23 83.4 0.0 4.3e-23 81.9 0.0 1.8 2 0 0 2 2 2 1 Enolase, N-terminal domain Intein_splicing PF14890.6 RLN70093.1 - 0.00072 19.5 0.0 0.0031 17.5 0.0 2.3 1 1 0 1 1 1 1 Intein splicing domain E1-E2_ATPase PF00122.20 RLN70094.1 - 7e-49 165.8 4.4 8e-48 162.3 2.6 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 RLN70094.1 - 2.9e-36 124.9 16.7 2.1e-18 66.7 0.0 4.0 4 0 0 4 4 4 3 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 RLN70094.1 - 1.8e-25 88.9 0.1 3.8e-25 87.8 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RLN70094.1 - 3.1e-20 73.4 0.0 1e-09 39.0 0.0 3.7 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RLN70094.1 - 3.7e-12 45.8 0.0 7.8e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RLN70094.1 - 0.00014 21.7 2.5 0.0052 16.6 0.5 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase ALG11_N PF15924.5 RLN70095.1 - 6.1e-73 245.3 0.2 8.7e-73 244.8 0.2 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 RLN70095.1 - 3.2e-26 91.9 0.0 6.3e-26 90.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RLN70095.1 - 2e-16 60.7 0.0 4.2e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 RLN70095.1 - 0.0011 19.3 0.0 0.0026 18.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 ADH_N PF08240.12 RLN70096.1 - 1.3e-10 41.1 0.0 2.8e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 RLN70096.1 - 0.00018 21.4 0.0 0.00038 20.3 0.0 1.6 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase tRNA_Me_trans PF03054.16 RLN70103.1 - 1.1e-112 376.4 0.0 1.3e-106 356.4 0.0 2.1 2 0 0 2 2 2 2 tRNA methyl transferase NAD_synthase PF02540.17 RLN70103.1 - 1.3e-06 27.7 0.0 1.2e-05 24.6 0.0 2.3 3 0 0 3 3 3 1 NAD synthase ThiI PF02568.14 RLN70103.1 - 5.5e-05 22.8 0.0 0.00032 20.4 0.0 2.1 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) PhyH PF05721.13 RLN70103.1 - 0.00024 21.4 0.0 0.001 19.4 0.0 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 RLN70103.1 - 0.00062 18.6 0.0 0.024 13.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1479) QueC PF06508.13 RLN70103.1 - 0.0018 17.8 0.0 0.0052 16.3 0.0 1.8 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 RLN70103.1 - 0.027 14.2 0.2 0.18 11.6 0.2 2.1 1 1 0 1 1 1 0 PP-loop family Vac14_Fig4_bd PF11916.8 RLN70104.1 - 4.1e-64 215.5 11.2 5.4e-38 130.4 1.7 3.2 2 1 1 3 3 3 2 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 RLN70104.1 - 1.2e-49 166.8 1.0 1.8e-42 143.8 0.0 4.5 2 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 RLN70104.1 - 2.6e-14 52.1 5.0 8.7e-05 22.5 0.0 7.4 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 RLN70104.1 - 1e-08 35.5 1.1 0.07 13.7 0.0 5.3 4 0 0 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 RLN70104.1 - 2.3e-08 34.2 9.6 0.003 17.6 0.0 5.4 4 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 RLN70104.1 - 3.4e-07 30.1 0.5 0.0011 18.5 0.0 4.2 3 2 2 5 5 5 1 CLASP N terminal HEAT_2 PF13646.6 RLN70104.1 - 4.4e-07 30.2 1.5 1.3 9.5 0.0 5.4 4 1 1 5 5 5 2 HEAT repeats Tti2 PF10521.9 RLN70104.1 - 0.0014 18.3 0.1 0.28 10.7 0.0 3.2 3 0 0 3 3 3 1 Tti2 family RTP1_C1 PF10363.9 RLN70104.1 - 0.0038 17.4 4.0 0.046 13.9 0.4 3.7 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 ParcG PF10274.9 RLN70104.1 - 0.01 16.0 1.3 0.085 13.0 0.4 2.6 1 1 1 2 2 2 0 Parkin co-regulated protein Arm PF00514.23 RLN70104.1 - 0.06 13.4 0.8 18 5.6 0.0 4.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat IFRD PF05004.13 RLN70104.1 - 0.063 12.4 1.4 2.2 7.3 0.2 3.5 3 1 0 4 4 4 0 Interferon-related developmental regulator (IFRD) Glutaredoxin2_C PF04399.13 RLN70104.1 - 0.12 12.3 0.5 24 4.8 0.0 2.8 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain RasGEF_N_2 PF14663.6 RLN70104.1 - 0.63 10.5 6.9 10 6.6 0.0 4.0 4 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Glyco_transf_28 PF03033.20 RLN70105.1 - 7.5e-22 77.9 0.1 3.4e-21 75.7 0.1 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Seipin PF06775.14 RLN70114.1 - 5.7e-51 173.4 1.1 1.1e-50 172.5 1.1 1.5 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Ank_2 PF12796.7 RLN70115.1 - 2.1e-75 249.4 20.4 5.6e-14 52.5 0.1 8.5 4 4 5 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.30 RLN70115.1 - 8e-54 177.9 32.1 2e-06 28.0 0.2 13.8 11 2 2 13 13 13 11 Ankyrin repeat Ank_3 PF13606.6 RLN70115.1 - 2.3e-49 159.6 13.1 0.00029 21.0 0.0 15.3 16 0 0 16 16 16 11 Ankyrin repeat Ank_4 PF13637.6 RLN70115.1 - 1.9e-47 159.0 16.8 6.4e-08 33.0 0.1 10.9 5 4 8 13 13 13 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN70115.1 - 9.9e-46 153.2 33.2 2.1e-06 27.9 0.3 13.5 4 4 10 14 14 14 12 Ankyrin repeats (many copies) Ribosomal_S11 PF00411.19 RLN70115.1 - 0.14 12.6 10.6 0.054 13.9 1.9 3.5 3 0 0 3 3 3 0 Ribosomal protein S11 Pkinase_Tyr PF07714.17 RLN70116.1 - 3.3e-29 102.0 0.0 5e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN70116.1 - 3e-19 69.4 0.0 4.2e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF1180 PF06679.12 RLN70116.1 - 0.00051 20.5 0.8 0.0013 19.2 0.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) TMEM154 PF15102.6 RLN70116.1 - 0.0086 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family DUF5305 PF17231.2 RLN70116.1 - 0.031 13.7 0.1 0.065 12.6 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF4083 PF13314.6 RLN70116.1 - 0.052 13.5 1.8 0.11 12.5 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) ASFV_J13L PF05568.11 RLN70116.1 - 1.4 8.7 6.1 0.33 10.7 2.3 1.9 1 1 0 1 1 1 0 African swine fever virus J13L protein DUF3149 PF11346.8 RLN70116.1 - 4.3 7.0 10.3 8.3 6.1 10.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) FPN1 PF06963.12 RLN70117.1 - 7.7e-86 288.4 12.0 9e-86 288.1 12.0 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) SDF PF00375.18 RLN70119.1 - 3.8e-85 286.3 24.6 5.9e-66 223.1 17.7 2.1 2 0 0 2 2 2 2 Sodium:dicarboxylate symporter family RICTOR_V PF14668.6 RLN70119.1 - 0.87 9.9 4.9 1.9 8.8 0.0 2.9 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 YtxH PF12732.7 RLN70119.1 - 1.4 9.5 7.4 19 5.8 4.7 2.8 2 0 0 2 2 2 0 YtxH-like protein WASH-7_mid PF14744.6 RLN70120.1 - 6.4e-147 489.2 6.2 6.4e-147 489.2 6.2 1.7 2 0 0 2 2 2 1 WASH complex subunit 7 WASH-7_N PF14745.6 RLN70120.1 - 5.6e-121 404.8 0.0 5.4e-120 401.6 0.0 2.0 1 1 0 1 1 1 1 WASH complex subunit 7, N-terminal WASH-7_C PF14746.6 RLN70120.1 - 1.9e-58 197.0 6.7 9.4e-39 132.9 0.5 2.6 2 0 0 2 2 2 2 WASH complex subunit 7, C-terminal P_C PF06640.11 RLN70120.1 - 2.2 8.4 11.0 5.7 7.0 11.0 1.7 1 0 0 1 1 1 0 P protein C-terminus Osteoregulin PF07175.11 RLN70120.1 - 9.5 6.4 7.5 68 3.6 0.1 2.7 2 0 0 2 2 2 0 Osteoregulin SMN PF06003.12 RLN70121.1 - 1.6e-05 24.3 7.3 1.6e-05 24.3 7.3 1.7 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) CDK2AP PF09806.9 RLN70121.1 - 0.35 10.9 11.1 0.46 10.5 11.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein G_path_suppress PF15991.5 RLN70121.1 - 5.2 7.1 14.2 8.1 6.5 14.2 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 7tm_3 PF00003.22 RLN70126.1 - 1.4e-21 77.3 28.7 1.5e-12 47.8 5.0 3.2 1 1 2 3 3 3 2 7 transmembrane sweet-taste receptor of 3 GCPR Phage_Coat_A PF05357.13 RLN70126.1 - 0.077 12.8 0.1 0.24 11.2 0.1 1.9 1 0 0 1 1 1 0 Phage Coat Protein A AP2 PF00847.20 RLN70127.1 - 3.4e-06 27.2 0.3 0.00018 21.7 0.1 2.5 2 0 0 2 2 2 1 AP2 domain Transglut_core3 PF13471.6 RLN70127.1 - 0.16 11.9 0.3 0.48 10.3 0.3 1.8 1 1 0 1 1 1 0 Transglutaminase-like superfamily FYVE PF01363.21 RLN70130.1 - 1.4e-14 54.0 12.2 2.3e-14 53.3 12.2 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN70130.1 - 0.0036 17.5 7.9 0.0061 16.8 7.9 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger zf-RING_UBOX PF13445.6 RLN70130.1 - 0.12 12.4 3.6 0.26 11.3 3.6 1.6 1 1 0 1 1 1 0 RING-type zinc-finger C1_2 PF03107.16 RLN70130.1 - 0.38 11.1 9.2 0.18 12.1 5.8 2.0 2 0 0 2 2 2 0 C1 domain zf-RING_2 PF13639.6 RLN70130.1 - 0.41 11.0 10.5 0.92 9.9 10.6 1.6 1 1 0 1 1 1 0 Ring finger domain DZR PF12773.7 RLN70130.1 - 4.1 7.5 10.4 11 6.1 6.0 2.4 1 1 1 2 2 2 0 Double zinc ribbon Glyco_hydro_1 PF00232.18 RLN70131.1 - 6.6e-87 291.8 0.0 1.3e-45 155.6 0.1 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 1 Metallophos PF00149.28 RLN70131.1 - 1.7e-14 54.8 0.0 1.4e-13 51.8 0.0 2.4 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 RLN70131.1 - 4.9e-07 30.2 0.1 4.9e-07 30.2 0.1 2.1 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Xylo_C PF12529.8 RLN70132.1 - 0.14 11.8 0.0 0.23 11.0 0.0 1.4 1 1 0 1 1 1 0 Xylosyltransferase C terminal BK_channel_a PF03493.18 RLN70134.1 - 1.3e-19 70.2 0.0 4e-18 65.4 0.0 2.6 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit TrkA_N PF02254.18 RLN70134.1 - 2.9e-09 37.2 0.0 5.9e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 TrkA-N domain Ion_trans_2 PF07885.16 RLN70134.1 - 0.019 14.9 1.4 0.078 12.9 1.4 2.1 1 0 0 1 1 1 0 Ion channel Pkinase PF00069.25 RLN70135.1 - 3.1e-38 131.7 0.0 4e-37 128.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN70135.1 - 5.2e-14 52.2 0.2 2.1e-06 27.2 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RLN70135.1 - 0.0016 17.9 0.1 0.003 16.9 0.0 1.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 RLN70135.1 - 0.0055 16.6 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN70135.1 - 0.015 14.7 0.1 0.021 14.2 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 RLN70135.1 - 0.055 12.5 0.2 0.082 11.9 0.2 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 RLN70135.1 - 0.06 12.3 0.0 0.084 11.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_C PF00433.24 RLN70135.1 - 0.3 11.8 2.0 0.93 10.3 2.0 1.9 1 1 0 1 1 1 0 Protein kinase C terminal domain PLAC8 PF04749.17 RLN70136.1 - 2.7e-29 102.1 28.6 7e-17 62.3 14.6 3.3 2 2 0 2 2 2 2 PLAC8 family Virul_fac_BrkB PF03631.15 RLN70136.1 - 0.00025 20.7 3.4 0.0012 18.6 1.1 2.1 2 0 0 2 2 2 1 Virulence factor BrkB Stevor PF17410.2 RLN70136.1 - 0.0019 17.8 0.2 1.9 8.0 0.1 2.7 3 0 0 3 3 3 2 Subtelomeric Variable Open Reading frame Presenilin PF01080.17 RLN70136.1 - 0.05 12.4 0.5 0.25 10.0 0.1 1.9 2 0 0 2 2 2 0 Presenilin DUF2206 PF09971.9 RLN70136.1 - 0.21 10.3 2.7 1.6 7.4 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) DUF4006 PF13179.6 RLN70136.1 - 2.1 8.3 4.7 0.46 10.4 0.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF4006) DUF5518 PF17647.1 RLN70136.1 - 5.2 7.2 10.3 5.5 7.2 0.0 3.3 4 0 0 4 4 4 0 Family of unknown function (DUF5518) PLAC8 PF04749.17 RLN70137.1 - 3.9e-20 72.7 24.6 2e-19 70.4 24.6 1.9 1 1 0 1 1 1 1 PLAC8 family SGP PF17228.2 RLN70137.1 - 6.5 7.7 15.1 0.82 10.6 9.3 2.0 2 0 0 2 2 2 0 Sulphur globule protein PGAP1 PF07819.13 RLN70139.1 - 0.0011 18.7 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 RLN70139.1 - 0.087 12.3 0.1 0.7 9.4 0.1 2.1 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Pkinase_Tyr PF07714.17 RLN70141.1 - 1.6e-38 132.5 0.0 8e-29 100.7 0.0 3.5 4 0 0 4 4 4 3 Protein tyrosine kinase Pkinase PF00069.25 RLN70141.1 - 1.6e-34 119.5 0.0 4.1e-26 91.9 0.0 3.2 3 0 0 3 3 3 2 Protein kinase domain Calici_coat_C PF08435.11 RLN70141.1 - 0.079 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal UBA_4 PF14555.6 RLN70143.1 - 1.3e-10 40.9 2.5 2.2e-10 40.2 1.0 2.0 1 1 1 2 2 2 1 UBA-like domain N_BRCA1_IG PF16158.5 RLN70143.1 - 7.8e-10 39.4 0.2 3.2e-09 37.4 0.0 1.9 1 1 1 2 2 2 1 Ig-like domain from next to BRCA1 gene TAP_C PF03943.13 RLN70143.1 - 0.087 12.5 0.3 0.087 12.5 0.3 1.7 2 0 0 2 2 2 0 TAP C-terminal domain HECT PF00632.25 RLN70144.1 - 2.2e-34 119.3 0.0 2.7e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Amidinotransf PF02274.17 RLN70145.1 - 5.3e-09 35.6 0.0 5.2e-07 29.1 0.0 3.2 3 1 0 3 3 3 1 Amidinotransferase PAD_porph PF04371.15 RLN70145.1 - 0.05 12.9 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Porphyromonas-type peptidyl-arginine deiminase ArfGap PF01412.18 RLN70148.1 - 4.5e-28 97.7 0.0 1e-27 96.5 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TTL PF03133.15 RLN70149.1 - 1.2e-28 100.1 0.0 4.5e-28 98.2 0.0 1.9 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family EGF_2 PF07974.13 RLN70149.1 - 0.00033 21.0 13.6 0.0006 20.1 13.6 1.4 1 0 0 1 1 1 1 EGF-like domain EB PF01683.18 RLN70149.1 - 0.025 14.9 3.8 0.055 13.8 3.8 1.5 1 0 0 1 1 1 0 EB module EGF_Tenascin PF18720.1 RLN70149.1 - 0.086 12.9 9.0 0.19 11.8 9.0 1.6 1 0 0 1 1 1 0 Tenascin EGF domain ATP-synt_C PF00137.21 RLN70155.1 - 9.5e-34 115.6 35.9 1.9e-23 82.5 14.3 2.5 3 0 0 3 3 3 2 ATP synthase subunit C ATP-synt_C PF00137.21 RLN70156.1 - 9.5e-34 115.6 35.9 1.9e-23 82.5 14.3 2.5 3 0 0 3 3 3 2 ATP synthase subunit C Med22 PF06179.12 RLN70158.1 - 4.1e-11 43.0 0.3 3.1e-10 40.2 0.3 1.9 1 1 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DDE_1 PF03184.19 RLN70159.1 - 1.1e-06 28.4 0.0 1.6e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 RLN70161.1 - 1.6e-07 31.0 0.1 4.6e-07 29.5 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 RLN70161.1 - 2.8e-07 30.1 0.0 6.4e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_1 PF11427.8 RLN70161.1 - 1.3e-06 28.2 0.0 2.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Tc3 transposase HTH_29 PF13551.6 RLN70161.1 - 0.093 12.8 0.1 0.24 11.5 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 RLN70161.1 - 0.11 12.6 0.4 0.51 10.5 0.1 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain EVI2A PF05399.11 RLN70161.1 - 0.2 11.2 2.3 7.1 6.1 0.1 2.4 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) SMK-1 PF04802.15 RLN70162.1 - 7.8e-19 68.2 0.0 1.8e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 DUF4820 PF16091.5 RLN70162.1 - 0.75 9.1 7.3 0.087 12.2 1.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4820) FAD_binding_1 PF00667.20 RLN70163.1 - 1.6e-28 99.8 0.0 3e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 RLN70163.1 - 4.8e-19 69.0 0.0 9.8e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 RLN70163.1 - 6e-08 33.3 0.0 1.3e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain TatD_DNase PF01026.21 RLN70164.1 - 1.7e-38 132.5 0.0 5.9e-38 130.7 0.0 1.7 1 1 0 1 1 1 1 TatD related DNase Ank_5 PF13857.6 RLN70166.1 - 4.2e-08 33.3 0.0 2.8e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) FYVE PF01363.21 RLN70166.1 - 9.1e-07 28.9 4.0 1.7e-06 28.0 4.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger Ank_2 PF12796.7 RLN70166.1 - 4.8e-05 23.9 0.0 0.0001 22.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN70166.1 - 0.00021 21.8 0.0 0.00041 20.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 RLN70166.1 - 0.057 13.9 0.3 0.7 10.5 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 RLN70166.1 - 0.12 13.0 0.0 1.8 9.4 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat DUF3835 PF12927.7 RLN70166.1 - 0.56 11.1 6.1 0.96 10.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) Crust_neurohorm PF01147.17 RLN70166.1 - 4.8 7.1 10.3 0.16 11.8 0.5 2.4 1 1 1 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family CoA_binding PF02629.19 RLN70167.1 - 9.5e-23 80.7 0.2 1.9e-22 79.8 0.2 1.5 1 0 0 1 1 1 1 CoA binding domain KASH_CCD PF14662.6 RLN70169.1 - 0.00017 21.5 9.9 0.00017 21.5 9.9 5.7 2 1 2 5 5 5 2 Coiled-coil region of CCDC155 or KASH HALZ PF02183.18 RLN70169.1 - 0.15 12.3 0.2 0.15 12.3 0.2 8.9 9 1 1 10 10 10 0 Homeobox associated leucine zipper YabA PF06156.13 RLN70169.1 - 0.16 12.6 51.1 0.39 11.4 3.6 6.9 3 1 3 7 7 7 0 Initiation control protein YabA DUF1664 PF07889.12 RLN70169.1 - 1.7 8.7 36.8 0.21 11.6 2.5 5.2 5 1 0 5 5 5 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 RLN70169.1 - 2.1 8.1 56.5 0.039 13.8 9.4 5.8 2 1 2 5 5 5 0 Protein of unknown function (DUF724) ADIP PF11559.8 RLN70169.1 - 6.9 6.7 67.9 3.3 7.8 4.5 6.4 3 1 2 6 6 6 0 Afadin- and alpha -actinin-Binding PDZ_6 PF17820.1 RLN70170.1 - 3.2e-07 30.1 0.2 6e-07 29.2 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RLN70170.1 - 0.00019 21.7 0.1 0.00071 19.9 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 RLN70170.1 - 0.031 14.6 0.1 0.13 12.6 0.1 2.0 2 0 0 2 2 2 0 PDZ domain Chitin_synth_1 PF01644.17 RLN70171.1 - 3.2e-50 170.3 0.0 5.3e-50 169.6 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 RLN70171.1 - 6.2e-24 84.5 0.2 2.6e-20 72.6 0.0 3.1 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 RLN70171.1 - 4.9e-09 36.4 2.9 4.9e-09 36.4 2.9 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Chitin_synth_1N PF08407.11 RLN70171.1 - 1e-05 25.3 0.0 4.4e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_tranf_2_3 PF13641.6 RLN70171.1 - 2e-05 24.6 0.0 4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Citrate_synt PF00285.21 RLN70172.1 - 1.7e-103 346.5 0.0 2.3e-103 346.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain CDC27 PF09507.10 RLN70173.1 - 6.6e-06 25.8 45.9 0.00013 21.6 42.9 2.9 2 1 0 2 2 2 1 DNA polymerase subunit Cdc27 S1_2 PF13509.6 RLN70173.1 - 0.12 12.5 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 S1 domain TIP49 PF06068.13 RLN70174.1 - 1.9e-157 524.0 1.3 2.8e-157 523.4 1.3 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 RLN70174.1 - 2.4e-25 88.4 0.6 6.8e-25 87.0 0.6 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain DUF2723 PF11028.8 RLN70174.1 - 8.4e-16 58.4 2.0 1.6e-15 57.4 2.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2723) AAA PF00004.29 RLN70174.1 - 1.1e-08 35.6 1.1 4.7e-06 27.1 0.1 3.1 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 RLN70174.1 - 6.8e-06 25.9 0.3 0.0023 17.7 0.1 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 RLN70174.1 - 7.6e-06 25.4 0.1 1.4e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_5 PF07728.14 RLN70174.1 - 1.7e-05 24.8 0.1 0.0018 18.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RLN70174.1 - 0.0001 22.6 0.1 0.14 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 RLN70174.1 - 0.00075 18.9 0.7 0.014 14.7 0.4 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 RLN70174.1 - 0.0011 19.4 1.8 0.0023 18.4 0.2 2.4 2 1 0 2 2 1 1 AAA ATPase domain NACHT PF05729.12 RLN70174.1 - 0.0011 18.9 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 RLN70174.1 - 0.0015 18.9 1.0 0.01 16.2 1.0 2.2 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 RLN70174.1 - 0.0067 16.1 0.1 1.6 8.4 0.1 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.6 RLN70174.1 - 0.0073 15.9 0.2 0.0073 15.9 0.2 2.0 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 RLN70174.1 - 0.015 14.7 0.1 0.027 13.8 0.1 1.4 1 0 0 1 1 1 0 KaiC TsaE PF02367.17 RLN70174.1 - 0.02 14.9 0.2 0.055 13.5 0.2 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 RLN70174.1 - 0.05 12.9 0.2 0.098 11.9 0.2 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 RLN70174.1 - 0.083 12.4 0.3 0.22 11.0 0.1 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 RLN70174.1 - 0.11 13.0 0.2 0.59 10.7 0.0 2.3 3 0 0 3 3 1 0 AAA domain Parvo_NS1 PF01057.17 RLN70174.1 - 0.16 11.0 0.2 0.29 10.2 0.2 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.6 RLN70174.1 - 0.18 12.0 0.7 0.48 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain DNA_primase_S PF01896.19 RLN70175.1 - 3.8e-55 186.7 0.0 5.1e-55 186.3 0.0 1.2 1 0 0 1 1 1 1 DNA primase small subunit Ribosomal_S8e PF01201.22 RLN70176.1 - 1.1e-52 177.9 1.7 1.6e-52 177.3 1.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S8e Lipocalin_5 PF13924.6 RLN70178.1 - 0.05 13.4 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipocalin-like domain Prefoldin PF02996.17 RLN70179.1 - 1.5e-18 66.8 0.2 1.5e-18 66.8 0.2 2.3 2 0 0 2 2 2 1 Prefoldin subunit TPR_1 PF00515.28 RLN70179.1 - 1.5e-15 56.3 10.6 9.1e-06 25.3 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN70179.1 - 4.6e-13 48.2 13.8 2.9e-06 27.0 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 RLN70179.1 - 8.8e-06 25.8 8.7 0.00081 19.5 3.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN70179.1 - 1.1e-05 25.0 0.7 0.0044 16.7 0.4 2.8 2 1 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 RLN70179.1 - 2.3e-05 24.2 6.0 0.29 11.5 0.0 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN70179.1 - 0.00051 20.6 15.6 0.073 13.7 10.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN70179.1 - 0.00074 19.8 12.9 0.0091 16.3 6.3 3.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN70179.1 - 0.0036 17.6 2.6 0.097 13.1 0.6 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat NYD-SP12_N PF15015.6 RLN70179.1 - 0.0059 15.0 0.3 0.01 14.3 0.3 1.3 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal TPR_14 PF13428.6 RLN70179.1 - 0.032 15.1 13.0 0.53 11.3 0.3 3.8 1 1 2 3 3 3 0 Tetratricopeptide repeat Nuc_deoxyri_tr3 PF11071.8 RLN70179.1 - 0.072 13.1 0.8 0.27 11.3 0.0 2.2 2 1 1 3 3 3 0 Nucleoside 2-deoxyribosyltransferase YtoQ MerR-DNA-bind PF09278.11 RLN70179.1 - 0.12 12.9 0.1 0.12 12.9 0.1 3.4 5 0 0 5 5 3 0 MerR, DNA binding TPR_19 PF14559.6 RLN70179.1 - 0.62 10.6 10.5 1.9 9.0 4.9 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 RLN70179.1 - 1 9.4 5.0 11 6.1 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat NPV_P10 PF05531.12 RLN70179.1 - 5 7.7 7.4 3.7 8.1 0.6 2.7 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein Vfa1 PF08432.10 RLN70179.1 - 8.7 6.6 17.2 1.5e+02 2.6 8.7 3.1 2 1 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 EF1_GNE PF00736.19 RLN70180.1 - 9.3e-32 109.1 1.2 1.8e-31 108.1 1.2 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain CDC27 PF09507.10 RLN70180.1 - 0.0059 16.1 8.4 0.0067 15.9 8.4 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Pox_Ag35 PF03286.14 RLN70180.1 - 0.012 15.4 6.8 0.018 14.9 6.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3381 PF11861.8 RLN70180.1 - 0.042 13.7 4.7 0.065 13.0 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Sigma70_ner PF04546.13 RLN70180.1 - 0.052 13.4 5.6 0.071 13.0 5.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region YL1 PF05764.13 RLN70180.1 - 0.082 13.0 8.8 0.11 12.5 8.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein PBP1_TM PF14812.6 RLN70180.1 - 0.085 13.2 8.6 0.18 12.2 8.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal VIR_N PF15912.5 RLN70180.1 - 0.085 12.4 1.8 0.11 12.0 1.8 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Cwf_Cwc_15 PF04889.12 RLN70180.1 - 0.16 11.7 9.5 0.22 11.2 9.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 RLN70180.1 - 0.22 11.2 3.5 0.37 10.5 3.5 1.4 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 RLN70180.1 - 0.38 9.0 6.8 0.54 8.5 6.8 1.2 1 0 0 1 1 1 0 CDC45-like protein IFT57 PF10498.9 RLN70180.1 - 0.64 8.9 6.2 0.9 8.4 6.2 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TRAP_alpha PF03896.16 RLN70180.1 - 1.2 8.3 5.0 1.6 7.9 5.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit eIF3_subunit PF08597.10 RLN70180.1 - 2.2 8.1 23.2 3.5 7.5 23.2 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CENP-B_dimeris PF09026.10 RLN70180.1 - 2.3 8.7 11.1 4.1 7.9 11.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 RLN70180.1 - 2.7 6.0 9.9 3.3 5.7 9.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi PAC1 PF16094.5 RLN70180.1 - 2.8 7.0 5.6 5 6.2 5.6 1.4 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 GST_C PF00043.25 RLN70180.1 - 5.7 7.2 6.4 0.75 10.1 0.1 2.6 2 2 0 2 2 2 0 Glutathione S-transferase, C-terminal domain FBPase PF00316.20 RLN70181.1 - 1.9e-101 337.3 3.9 1.3e-63 213.9 0.2 3.1 2 1 1 3 3 3 3 Fructose-1-6-bisphosphatase, N-terminal domain DUF1653 PF07866.11 RLN70181.1 - 7.8e-05 22.9 0.0 0.78 10.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1653) OCRE PF17780.1 RLN70181.1 - 0.047 13.7 0.0 14 5.8 0.0 2.6 2 0 0 2 2 2 0 OCRE domain WD40 PF00400.32 RLN70182.1 - 3.2e-14 53.1 15.0 9.9e-05 23.0 0.1 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ_3 PF13570.6 RLN70182.1 - 0.013 15.9 0.2 0.17 12.4 0.0 2.6 2 0 0 2 2 2 0 PQQ-like domain PQQ PF01011.21 RLN70182.1 - 0.013 15.4 0.0 0.039 13.9 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat Cytochrom_D1 PF02239.16 RLN70182.1 - 0.021 13.4 0.4 0.059 11.9 0.1 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF1547 PF07577.11 RLN70182.1 - 0.15 12.5 0.5 0.47 10.9 0.0 2.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1547) 2OG-FeII_Oxy_2 PF13532.6 RLN70183.1 - 2.3e-20 73.6 0.0 4.1e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 RLN70183.1 - 5.8e-13 49.3 0.2 1.4e-12 48.1 0.2 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN70183.1 - 1.1e-10 42.1 0.3 2.6e-10 40.9 0.3 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 RLN70183.1 - 1.6e-05 24.9 0.0 2.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_31 PF13847.6 RLN70183.1 - 0.00061 19.6 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN70183.1 - 0.0017 19.1 0.1 0.004 17.9 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 RLN70183.1 - 0.0034 17.0 0.0 0.0063 16.1 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 RLN70183.1 - 0.042 12.8 0.0 0.074 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Bud13 PF09736.9 RLN70184.1 - 2.3e-41 141.5 8.9 2.3e-41 141.5 8.9 4.1 3 2 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex Nucleoside_tran PF01733.18 RLN70185.1 - 1.3e-54 185.7 7.9 1.3e-54 185.7 7.9 1.9 2 0 0 2 2 2 1 Nucleoside transporter FAM176 PF14851.6 RLN70185.1 - 0.41 10.3 1.4 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 FAM176 family NAD_binding_10 PF13460.6 RLN70186.1 - 3.5e-13 49.8 0.0 1.8e-12 47.6 0.0 2.1 1 1 1 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 RLN70186.1 - 9.5e-12 45.0 0.0 6.2e-11 42.3 0.0 2.0 1 1 1 2 2 2 1 NmrA-like family LpxI_N PF17930.1 RLN70186.1 - 0.00099 19.0 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 LpxI N-terminal domain Glyco_transf_4 PF13439.6 RLN70186.1 - 0.012 15.6 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 PglD_N PF17836.1 RLN70186.1 - 0.054 14.1 0.0 20 5.9 0.0 2.5 2 0 0 2 2 2 0 PglD N-terminal domain RmlD_sub_bind PF04321.17 RLN70186.1 - 0.082 12.0 0.1 0.24 10.5 0.1 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain 3HCDH_N PF02737.18 RLN70186.1 - 0.099 12.5 0.0 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SHIPPO-rpt PF07004.12 RLN70188.1 - 2.3 9.3 6.5 36 5.5 0.0 4.3 5 1 0 5 5 5 0 Sperm-tail PG-rich repeat tRNA_m1G_MT PF01746.21 RLN70189.1 - 4.1e-22 78.8 0.0 1.5e-21 77.0 0.0 1.8 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Peptidase_C48 PF02902.19 RLN70201.1 - 5.8e-08 32.8 0.1 1e-07 32.1 0.1 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Vault PF01505.18 RLN70202.1 - 8.4e-52 173.1 8.9 3.9e-17 62.1 0.1 5.6 5 0 0 5 5 5 4 Major Vault Protein repeat domain Vault_3 PF17795.1 RLN70202.1 - 1.3e-38 130.8 1.0 7.4e-33 112.4 0.1 3.8 3 0 0 3 3 3 2 Major Vault Protein Repeat domain Vault_2 PF17794.1 RLN70202.1 - 2.9e-30 104.4 1.7 2.9e-16 59.6 0.1 3.7 4 0 0 4 4 4 2 Major Vault Protein repeat domain Vault_4 PF17796.1 RLN70202.1 - 5.2e-25 87.3 0.0 2.1e-22 78.9 0.0 2.8 2 0 0 2 2 2 2 Major Vault Protein repeat domain DUF3601 PF12208.8 RLN70202.1 - 0.026 14.6 0.0 18 5.5 0.0 4.0 2 1 2 4 4 4 0 Domain of unknown function (DUF3601) efThoc1 PF11957.8 RLN70203.1 - 2.3e-101 339.9 0.0 3.3e-101 339.4 0.0 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Ank_2 PF12796.7 RLN70203.1 - 1.5e-09 38.3 0.0 3.8e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN70203.1 - 5.3e-07 30.1 0.1 1.3e-06 28.9 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN70203.1 - 2e-06 27.7 0.1 0.19 12.4 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 RLN70203.1 - 6.3e-05 23.2 0.0 0.43 11.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 RLN70203.1 - 0.0001 22.5 0.5 0.012 15.9 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) fn3 PF00041.21 RLN70223.1 - 1.1e-49 166.7 22.7 3e-14 53.1 0.0 10.8 11 0 0 11 11 11 9 Fibronectin type III domain DUF2369 PF10179.9 RLN70223.1 - 1.9e-11 44.2 1.3 0.0046 17.3 0.0 6.4 6 0 0 6 6 6 4 Uncharacterised conserved protein (DUF2369) Pur_ac_phosph_N PF16656.5 RLN70223.1 - 1.1e-10 42.0 20.0 4.9e-05 23.8 0.1 9.0 10 2 0 10 10 10 3 Purple acid Phosphatase, N-terminal domain NAR2 PF16974.5 RLN70223.1 - 0.13 11.7 5.7 17 4.7 0.0 4.6 6 0 0 6 6 6 0 High-affinity nitrate transporter accessory Pkinase PF00069.25 RLN70224.1 - 1.2e-77 260.8 0.0 2e-77 260.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN70224.1 - 4.7e-43 147.4 0.0 7.6e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 RLN70224.1 - 1.2e-14 53.2 0.0 0.0014 18.7 0.0 6.2 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 RLN70224.1 - 4.3e-10 39.9 0.1 0.00012 22.5 0.0 3.9 3 0 0 3 3 2 2 HEAT-like repeat Arm PF00514.23 RLN70224.1 - 4.2e-08 32.9 3.3 0.044 13.8 0.0 5.4 6 0 0 6 6 5 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN70224.1 - 4.2e-08 33.5 0.0 0.00071 19.9 0.0 5.0 4 1 1 5 5 5 2 HEAT repeats Pkinase_fungal PF17667.1 RLN70224.1 - 1.2e-05 24.3 0.0 2.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Ephrin_rec_like PF07699.13 RLN70224.1 - 0.0011 18.6 12.8 0.0073 16.0 2.8 2.5 1 1 1 2 2 2 1 Putative ephrin-receptor like Haspin_kinase PF12330.8 RLN70224.1 - 0.0014 17.7 0.2 0.0024 16.9 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 RLN70224.1 - 0.0014 18.3 0.1 0.017 14.7 0.1 2.4 1 1 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 RLN70224.1 - 0.0015 17.9 0.0 0.0065 15.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Cnd1 PF12717.7 RLN70224.1 - 0.0023 18.0 0.0 3 7.9 0.0 3.6 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 APH PF01636.23 RLN70224.1 - 0.016 15.1 0.0 0.11 12.4 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Furin-like PF00757.20 RLN70224.1 - 0.086 12.7 3.4 0.2 11.5 3.4 1.5 1 0 0 1 1 1 0 Furin-like cysteine rich region Kdo PF06293.14 RLN70224.1 - 0.097 12.0 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 RLN70224.1 - 0.14 11.8 0.1 0.42 10.2 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TNFR_c6 PF00020.18 RLN70224.1 - 0.59 10.6 3.5 4.6 7.7 0.0 3.1 2 1 0 3 3 3 0 TNFR/NGFR cysteine-rich region NCD3G PF07562.14 RLN70224.1 - 0.81 9.7 9.4 8.8 6.4 3.1 2.6 1 1 1 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Ank_2 PF12796.7 RLN70225.1 - 1.4e-25 89.7 0.1 2.8e-14 53.5 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN70225.1 - 1e-18 67.2 3.7 0.00013 22.1 0.0 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN70225.1 - 4.1e-18 64.9 4.0 7.6e-05 23.0 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat FYVE PF01363.21 RLN70225.1 - 9.4e-17 60.9 13.9 1.5e-16 60.3 13.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger Ank_3 PF13606.6 RLN70225.1 - 4.3e-16 57.4 0.7 0.0088 16.5 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 RLN70225.1 - 1.7e-13 50.8 4.6 4.1e-08 33.6 0.0 5.2 4 2 2 6 6 6 2 Ankyrin repeats (many copies) FYVE_2 PF02318.16 RLN70225.1 - 0.58 10.4 13.2 3.2 8.0 13.6 1.9 1 1 1 2 2 2 0 FYVE-type zinc finger GF_recep_IV PF14843.6 RLN70225.1 - 0.59 9.9 11.8 0.93 9.3 11.8 1.2 1 0 0 1 1 1 0 Growth factor receptor domain IV BTK PF00779.19 RLN70239.1 - 0.26 11.2 3.6 0.22 11.4 0.9 2.1 2 0 0 2 2 2 0 BTK motif Pkinase PF00069.25 RLN70241.1 - 4.3e-54 183.7 0.0 4.6e-49 167.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN70241.1 - 4e-29 101.7 0.0 6.4e-27 94.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RLN70241.1 - 8.5e-08 31.9 0.0 1.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RLN70241.1 - 2.6e-05 23.2 0.0 3.6e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN70241.1 - 0.083 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN70241.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PTPlike_phytase PF14566.6 RLN70242.1 - 5.1e-82 273.6 25.0 3.1e-49 167.1 1.0 3.5 3 0 0 3 3 3 2 Inositol hexakisphosphate DDRGK PF09756.9 RLN70242.1 - 1.2e-52 178.2 31.1 2.7e-52 177.1 31.1 1.6 1 0 0 1 1 1 1 DDRGK domain TOC159_MAD PF11886.8 RLN70242.1 - 0.11 11.4 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Translocase of chloroplast 159/132, membrane anchor domain DUF3877 PF12993.7 RLN70242.1 - 0.18 11.7 5.6 0.47 10.3 5.6 1.7 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) Y_phosphatase3 PF13350.6 RLN70242.1 - 0.34 10.8 6.3 6.9 6.6 0.0 3.2 3 0 0 3 3 3 0 Tyrosine phosphatase family DSPc PF00782.20 RLN70242.1 - 0.78 9.5 5.6 1.3 8.9 1.5 3.4 3 1 0 3 3 3 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RLN70242.1 - 2.5 7.6 8.5 1 8.9 0.1 3.2 3 0 0 3 3 3 0 Protein-tyrosine phosphatase TPH PF13868.6 RLN70243.1 - 9.5e-08 30.9 123.9 9.5e-08 30.9 123.9 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain NDC10_II PF16787.5 RLN70244.1 - 0.00041 19.5 0.0 0.00045 19.4 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 SNARE_assoc PF09335.11 RLN70245.1 - 3.5e-16 59.8 3.9 9.3e-16 58.4 3.9 1.7 1 0 0 1 1 1 1 SNARE associated Golgi protein MAD PF05557.13 RLN70245.1 - 0.48 8.7 14.6 0.65 8.3 14.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein TSC22 PF01166.18 RLN70245.1 - 1.4 9.3 5.5 3.3 8.1 1.6 2.6 1 1 1 2 2 2 0 TSC-22/dip/bun family V_ATPase_I PF01496.19 RLN70245.1 - 1.7 6.4 4.1 2.7 5.8 4.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.6 RLN70245.1 - 1.9 7.8 14.4 3.2 7.1 14.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding MPS2 PF17060.5 RLN70245.1 - 2 7.6 6.9 3.1 6.9 6.9 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 TMEM223 PF14640.6 RLN70246.1 - 0.016 15.4 0.0 0.025 14.8 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 223 MOSC_N PF03476.16 RLN70246.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 MOSC N-terminal beta barrel domain PUB PF09409.10 RLN70247.1 - 3.1e-17 62.3 0.0 5.2e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 PUB domain WLM PF08325.10 RLN70247.1 - 3.4e-11 43.6 0.1 8.1e-11 42.3 0.0 1.6 2 0 0 2 2 2 1 WLM domain ubiquitin PF00240.23 RLN70247.1 - 0.048 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family LPD11 PF18824.1 RLN70247.1 - 0.071 13.2 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 11 SNARE_assoc PF09335.11 RLN70248.1 - 3.3e-17 63.1 5.7 3.3e-17 63.1 5.7 3.0 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF4079 PF13301.6 RLN70248.1 - 0.35 11.0 6.5 0.063 13.4 1.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) RabGAP-TBC PF00566.18 RLN70249.1 - 7.4e-25 87.9 0.1 5.2e-12 45.9 0.0 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PH PF00169.29 RLN70249.1 - 6e-06 26.7 0.0 1.2e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF1989 PF09347.10 RLN70249.1 - 0.001 18.7 0.1 0.068 12.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1989) PH_8 PF15409.6 RLN70249.1 - 0.16 12.3 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain RhoGEF PF00621.20 RLN70251.1 - 1e-40 139.9 0.1 1.4e-35 123.2 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain FYVE PF01363.21 RLN70251.1 - 1.9e-17 63.1 8.7 4.3e-17 62.0 7.7 2.2 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.29 RLN70251.1 - 2.2e-06 28.1 1.1 0.016 15.7 0.0 4.2 3 1 0 3 3 3 1 PH domain PH_13 PF16652.5 RLN70251.1 - 0.00026 20.8 0.7 0.00026 20.8 0.7 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain FYVE_2 PF02318.16 RLN70251.1 - 0.012 15.8 4.8 0.063 13.5 4.8 2.3 1 0 0 1 1 1 0 FYVE-type zinc finger PH_11 PF15413.6 RLN70251.1 - 0.2 12.1 0.5 10 6.6 0.0 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain TF_Zn_Ribbon PF08271.12 RLN70251.1 - 7.5 6.2 6.0 1.9 8.0 0.9 2.5 1 1 1 2 2 2 0 TFIIB zinc-binding Ribophorin_II PF05817.14 RLN70252.1 - 1.6e-63 215.3 0.7 2.2e-63 214.9 0.7 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Y_Y_Y PF07495.13 RLN70252.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Y_Y_Y domain LEA_2 PF03168.13 RLN70252.1 - 0.13 12.8 0.7 3.4 8.3 0.1 2.4 2 0 0 2 2 2 0 Late embryogenesis abundant protein Peptidase_S28 PF05577.12 RLN70253.1 - 8.1e-75 252.2 0.0 1.2e-74 251.6 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 RLN70253.1 - 8.5e-06 25.4 0.1 1.6e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 RLN70253.1 - 0.0097 15.2 0.0 0.019 14.3 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF2920 PF11144.8 RLN70253.1 - 0.017 14.3 0.1 0.028 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Rac1 PF09632.10 RLN70255.1 - 0.015 14.5 1.0 0.02 14.1 0.9 1.3 1 1 0 1 1 1 0 Rac1-binding domain Fes1 PF08609.10 RLN70255.1 - 0.028 15.3 0.6 0.075 13.9 0.6 1.9 1 1 0 1 1 1 0 Nucleotide exchange factor Fes1 SNARE_assoc PF09335.11 RLN70256.1 - 5e-13 49.6 2.7 5e-13 49.6 2.7 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein FKBP_C PF00254.28 RLN70259.1 - 1.3e-20 73.5 0.0 2.6e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Sporozoite_P67 PF05642.11 RLN70259.1 - 0.87 7.6 7.4 0.45 8.5 5.4 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen SAPS PF04499.15 RLN70259.1 - 0.93 8.2 13.4 1.3 7.7 13.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 RLN70259.1 - 3.2 6.4 18.0 0.2 10.4 12.6 1.6 2 0 0 2 2 2 0 Presenilin U-box PF04564.15 RLN70264.1 - 7.1e-12 45.3 0.1 1.3e-11 44.5 0.1 1.4 1 0 0 1 1 1 1 U-box domain C2 PF00168.30 RLN70264.1 - 1.2e-07 31.9 0.0 1.1e-06 28.9 0.0 2.3 3 0 0 3 3 3 1 C2 domain zf-NOSIP PF15906.5 RLN70264.1 - 0.0017 18.4 0.0 0.0037 17.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 RLN70264.1 - 0.0018 18.0 0.1 0.0034 17.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit EamA PF00892.20 RLN70265.1 - 1.3e-15 57.8 40.3 1.6e-08 34.8 15.5 3.0 2 1 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 RLN70265.1 - 7.1e-06 25.7 10.8 7.1e-06 25.7 10.8 1.6 2 0 0 2 2 2 1 Solute carrier family 35 PUNUT PF16913.5 RLN70265.1 - 1.7e-05 24.2 1.9 1.7e-05 24.2 1.9 1.6 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport F-box-like PF12937.7 RLN70265.1 - 0.0021 17.9 0.4 0.015 15.2 0.0 2.6 2 0 0 2 2 2 1 F-box-like TPT PF03151.16 RLN70265.1 - 0.0053 16.1 5.6 0.0079 15.6 4.8 1.8 2 0 0 2 2 2 1 Triose-phosphate Transporter family F-box PF00646.33 RLN70265.1 - 0.031 14.2 0.5 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 F-box domain DUF4006 PF13179.6 RLN70265.1 - 0.74 9.8 4.6 2.2 8.3 0.0 3.4 4 0 0 4 4 4 0 Family of unknown function (DUF4006) MM_CoA_mutase PF01642.22 RLN70266.1 - 8.9e-25 87.2 0.7 1.2e-24 86.8 0.7 1.2 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 RLN70266.1 - 1.4e-14 54.1 0.1 2.7e-14 53.2 0.1 1.4 1 0 0 1 1 1 1 B12 binding domain IMPDH PF00478.25 RLN70266.1 - 0.0067 15.5 0.3 0.014 14.4 0.2 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Ketoacyl-synt_2 PF13723.6 RLN70266.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain XPA_C PF05181.12 RLN70267.1 - 2e-13 50.1 0.0 3.5e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 RLN70267.1 - 0.00039 20.4 1.8 0.00074 19.5 1.8 1.4 1 0 0 1 1 1 1 XPA protein N-terminal DUF4645 PF15488.6 RLN70267.1 - 0.034 13.6 0.2 0.053 13.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4645) zf-CSL PF05207.13 RLN70267.1 - 0.11 12.3 0.2 0.11 12.3 0.2 2.1 2 0 0 2 2 2 0 CSL zinc finger Pox_Ag35 PF03286.14 RLN70267.1 - 9.7 5.9 15.5 0.71 9.6 4.9 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein MULE PF10551.9 RLN70284.1 - 2e-18 66.6 0.1 3.7e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain SET PF00856.28 RLN70285.1 - 7.5e-09 36.2 0.2 2.5e-07 31.2 0.0 2.8 2 1 0 2 2 2 1 SET domain cNMP_binding PF00027.29 RLN70286.1 - 5.2e-09 36.0 0.0 9.8e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 RLN70286.1 - 7.2e-09 35.3 0.0 1.3e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 STAS domain DUF1077 PF06417.12 RLN70287.1 - 2.5e-29 101.7 4.1 4.1e-29 101.0 4.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1077) Peptidase_C13 PF01650.18 RLN70288.1 - 2.2e-97 325.6 0.1 4.7e-97 324.5 0.0 1.5 2 0 0 2 2 2 1 Peptidase C13 family RelB PF04221.12 RLN70288.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 RelB antitoxin PDZ_6 PF17820.1 RLN70290.1 - 5.6e-05 22.9 0.1 0.0012 18.6 0.0 2.8 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 RLN70290.1 - 0.0015 18.8 0.0 0.0057 17.0 0.0 2.0 1 1 0 1 1 1 1 PDZ domain PDZ_4 PF17816.1 RLN70290.1 - 0.026 14.9 0.1 2.5 8.6 0.1 2.5 2 0 0 2 2 2 0 PDZ domain GNAT_acetyltr_2 PF13718.6 RLN70290.1 - 0.41 10.0 1.2 0.9 8.9 0.0 1.9 2 0 0 2 2 2 0 GNAT acetyltransferase 2 Ank_5 PF13857.6 RLN70291.1 - 0.00012 22.2 0.0 0.0002 21.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN70291.1 - 0.00038 20.9 0.0 0.004 17.7 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN70291.1 - 0.014 16.0 0.0 0.018 15.6 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.30 RLN70291.1 - 0.12 12.9 0.0 23 5.6 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat Pkinase PF00069.25 RLN70302.1 - 0.0025 17.2 0.0 0.023 14.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN70302.1 - 0.027 13.8 0.0 0.09 12.0 0.0 1.8 2 1 0 2 2 2 0 Protein tyrosine kinase DUF348 PF03990.14 RLN70302.1 - 0.11 12.3 0.3 0.2 11.4 0.3 1.5 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain Peptidase_M48 PF01435.18 RLN70303.1 - 1e-23 84.2 0.0 2.1e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 Reprolysin_4 PF13583.6 RLN70303.1 - 0.0085 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 RLN70303.1 - 0.13 12.4 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 RLN70303.1 - 0.14 12.0 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 Matrixin ABC2_membrane PF01061.24 RLN70309.1 - 2.7e-65 219.7 64.3 6.5e-38 130.3 21.2 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN70309.1 - 4.4e-33 114.7 0.0 3.7e-16 59.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 RLN70309.1 - 4.6e-07 29.9 0.2 0.00091 19.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase ABC2_membrane_3 PF12698.7 RLN70309.1 - 1e-06 28.1 15.3 1e-06 28.1 15.3 2.8 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 RLN70309.1 - 1.2e-06 28.1 1.1 0.0062 16.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN70309.1 - 4.6e-05 23.7 0.0 0.41 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 RLN70309.1 - 8.1e-05 22.3 0.3 0.4 10.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 RLN70309.1 - 0.0001 22.3 0.2 2.7 7.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 RLN70309.1 - 0.00027 21.0 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 RLN70309.1 - 0.00032 21.2 0.1 1.4 9.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RLN70309.1 - 0.00049 20.7 1.1 0.57 10.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 RLN70309.1 - 0.0016 18.9 0.0 1.5 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 RLN70309.1 - 0.0016 18.6 0.0 0.84 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RLN70309.1 - 0.0023 17.7 2.8 1.3 8.8 0.3 2.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 RLN70309.1 - 0.0048 17.3 0.6 4.4 7.7 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PDR_assoc PF08370.11 RLN70309.1 - 0.0084 15.8 0.9 0.0084 15.8 0.9 2.7 2 0 0 2 2 2 1 Plant PDR ABC transporter associated AAA_28 PF13521.6 RLN70309.1 - 0.013 15.8 0.1 0.57 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 RLN70309.1 - 0.032 14.2 1.3 1.7 8.6 0.2 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 RLN70309.1 - 0.032 14.6 0.2 8.8 6.8 0.0 2.9 3 0 0 3 3 2 0 RNA helicase Zeta_toxin PF06414.12 RLN70309.1 - 0.065 12.5 2.1 5.9 6.1 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 RLN70309.1 - 0.073 13.0 2.1 4.2 7.3 0.4 2.5 2 0 0 2 2 2 0 NACHT domain MeaB PF03308.16 RLN70309.1 - 0.075 12.0 0.3 7.7 5.4 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 RLN70309.1 - 0.19 11.6 1.6 5.7 6.8 0.0 2.6 3 0 0 3 3 2 0 NTPase AAA_24 PF13479.6 RLN70309.1 - 0.23 11.1 5.1 2.1 8.0 0.3 2.7 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 RLN70309.1 - 0.31 10.6 2.7 6.9 6.2 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PRK PF00485.18 RLN70309.1 - 0.45 10.2 2.5 21 4.8 0.2 3.3 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_19 PF13245.6 RLN70309.1 - 0.89 9.9 2.9 5.9 7.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain DUF4489 PF14879.6 RLN70310.1 - 0.034 14.2 0.2 0.087 12.9 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4489) Lzipper-MIP1 PF14389.6 RLN70310.1 - 0.21 11.9 6.4 0.14 12.5 0.6 2.7 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Arf PF00025.21 RLN70311.1 - 2e-58 196.7 0.1 3.1e-58 196.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RLN70311.1 - 9.4e-14 51.7 0.3 1.7e-13 50.8 0.3 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RLN70311.1 - 3.2e-12 46.3 0.1 4.5e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 RLN70311.1 - 3.9e-09 36.2 0.1 6.3e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RLN70311.1 - 3e-08 33.2 0.8 2.5e-05 23.6 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 RLN70311.1 - 4.7e-07 29.9 0.0 1.3e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RLN70311.1 - 6.4e-05 22.4 0.1 8.9e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 RLN70311.1 - 0.00058 19.5 0.5 0.0059 16.2 0.3 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF4185 PF13810.6 RLN70311.1 - 0.0071 15.6 0.9 0.017 14.3 0.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4185) FeoB_N PF02421.18 RLN70311.1 - 0.043 13.3 0.1 0.11 12.0 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.6 RLN70311.1 - 0.065 13.3 0.2 0.14 12.2 0.2 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 RLN70311.1 - 0.09 12.7 0.5 0.86 9.5 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 RLN70311.1 - 0.14 12.3 0.1 0.25 11.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain cNMP_binding PF00027.29 RLN70311.1 - 0.15 12.1 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Invasin_D3 PF09134.10 RLN70311.1 - 0.17 12.2 2.9 0.41 11.0 2.2 2.1 1 1 1 2 2 2 0 Invasin, domain 3 AAA_22 PF13401.6 RLN70311.1 - 0.27 11.5 0.9 4.2 7.6 0.8 2.5 1 1 1 2 2 2 0 AAA domain Big_1 PF02369.16 RLN70311.1 - 1.6 8.8 9.0 9.9 6.3 0.4 3.0 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) PHO4 PF01384.20 RLN70313.1 - 1.7e-15 56.9 9.2 1.9e-15 56.8 9.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family IF-2B PF01008.17 RLN70314.1 - 1.8e-70 237.4 0.0 2.3e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Glyco_hydro81C PF17652.1 RLN70336.1 - 9.1e-112 373.8 2.9 1.6e-111 373.0 2.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 RLN70336.1 - 6.6e-53 180.0 0.5 6.6e-53 180.0 0.5 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 81 N-terminal domain Pkinase PF00069.25 RLN70337.1 - 1.8e-62 211.1 0.0 2.5e-62 210.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN70337.1 - 6.7e-37 127.2 0.0 1e-36 126.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 RLN70337.1 - 0.0015 19.2 0.0 0.0065 17.2 0.0 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 RLN70337.1 - 0.015 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 RLN70337.1 - 0.028 13.2 0.0 0.067 12.0 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 RLN70337.1 - 0.2 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF2052 PF09747.9 RLN70337.1 - 0.53 10.4 6.5 0.96 9.5 6.5 1.5 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DNA_ligase_A_N PF04675.14 RLN70338.1 - 2.9e-38 131.9 0.4 2.2e-37 129.0 0.2 2.4 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 RLN70338.1 - 4.9e-33 114.5 0.0 8.3e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 RLN70338.1 - 2.9e-13 50.2 0.4 1.5e-12 48.0 0.0 2.5 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.5 RLN70338.1 - 1.1e-12 48.2 0.0 5.4e-06 26.7 0.0 2.6 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 RLN70338.1 - 1.8e-06 28.3 0.0 4.2e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 RNA ligase PTCB-BRCT PF12738.7 RLN70338.1 - 1.6e-05 24.7 0.0 0.046 13.7 0.0 2.5 2 0 0 2 2 2 2 twin BRCT domain BRCT PF00533.26 RLN70338.1 - 3.5e-05 24.1 0.1 0.17 12.3 0.0 3.8 3 1 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 RLN70338.1 - 0.00041 20.6 0.0 0.053 13.8 0.0 2.5 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain DNA_ligase_IV PF11411.8 RLN70338.1 - 0.00042 20.4 0.0 0.00088 19.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase IV TPR_2 PF07719.17 RLN70373.1 - 0.0066 16.5 1.0 1.2 9.5 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat FYVE PF01363.21 RLN70374.1 - 0.067 13.3 7.8 0.13 12.4 7.8 1.4 1 0 0 1 1 1 0 FYVE zinc finger NepR PF18557.1 RLN70375.1 - 0.016 14.9 0.3 4 7.2 0.0 2.3 2 0 0 2 2 2 0 Anti-sigma factor NepR ABC_tran PF00005.27 RLN70376.1 - 1.4e-16 61.3 0.0 2.4e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN70376.1 - 1.4e-05 24.6 1.2 7.4e-05 22.3 1.2 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SRP54 PF00448.22 RLN70376.1 - 1.8e-05 24.4 0.2 3e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_21 PF13304.6 RLN70376.1 - 2.3e-05 24.3 2.8 0.0046 16.8 0.8 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 RLN70376.1 - 0.0014 18.4 1.4 0.0058 16.4 1.4 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 RLN70376.1 - 0.0042 16.4 0.1 0.0066 15.7 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 RLN70376.1 - 0.0058 16.4 0.2 0.012 15.3 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP-synt_ab PF00006.25 RLN70376.1 - 0.013 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_16 PF13191.6 RLN70376.1 - 0.02 15.3 0.6 0.038 14.4 0.6 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 RLN70376.1 - 0.12 12.6 0.5 0.28 11.4 0.4 1.8 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RLN70376.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase CobA_CobO_BtuR PF02572.15 RLN70376.1 - 0.38 11.0 1.5 1.4 9.2 1.5 1.9 1 1 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DUF4483 PF14825.6 RLN70377.1 - 2.3e-06 27.5 0.1 0.085 12.6 0.0 3.9 2 1 2 4 4 4 2 Domain of unknown function (DUF4483) WD40 PF00400.32 RLN70378.1 - 4.4e-23 81.1 15.9 2.2e-05 25.1 0.4 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN70378.1 - 4.8e-09 36.4 6.2 3e-05 24.2 1.0 3.7 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN70378.1 - 3.8e-06 26.1 0.5 0.047 12.6 0.0 3.6 3 1 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WDCP PF15390.6 RLN70378.1 - 0.036 12.5 0.1 0.051 12.0 0.1 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Picorna_P3A PF06363.11 RLN70379.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Picornaviridae P3A protein PKD_channel PF08016.12 RLN70381.1 - 2.2e-33 115.6 20.0 3.9e-30 104.9 17.8 3.0 1 1 1 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 RLN70381.1 - 4.5e-09 35.9 19.3 1.2e-08 34.5 19.3 1.7 1 1 0 1 1 1 1 Ion transport protein DUF2208 PF09973.9 RLN70381.1 - 0.77 9.3 8.4 0.04 13.5 2.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) PgaD PF13994.6 RLN70381.1 - 6.3 6.8 8.1 0.28 11.3 1.5 2.0 2 1 0 2 2 2 0 PgaD-like protein Myb_DNA-bind_4 PF13837.6 RLN70384.1 - 2.2 8.7 4.5 1.3 9.4 0.3 2.6 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Glyco_hydro_53 PF07745.13 RLN70386.1 - 2.9e-73 246.8 0.2 3.7e-73 246.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Glyco_hydro_53 PF07745.13 RLN70387.1 - 8.9e-73 245.2 0.0 1.1e-72 244.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 SpoIIIAH PF12685.7 RLN70388.1 - 0.034 14.0 0.7 0.052 13.4 0.7 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein CDRT4 PF15213.6 RLN70388.1 - 0.29 11.7 1.6 2.8 8.5 0.1 2.4 1 1 1 2 2 2 0 CMT1A duplicated region transcript 4 protein DUF440 PF04269.12 RLN70389.1 - 0.055 13.8 0.0 0.34 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF440 CENP-H PF05837.12 RLN70389.1 - 0.78 10.2 6.0 2 8.8 6.0 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Mito_fiss_reg PF05308.11 RLN70389.1 - 1 9.4 13.2 0.11 12.6 8.1 1.9 2 1 0 2 2 2 0 Mitochondrial fission regulator SpoIIIAH PF12685.7 RLN70389.1 - 6.7 6.5 7.8 2.3e+02 1.5 7.9 2.3 1 1 0 1 1 1 0 SpoIIIAH-like protein DUF1925 PF09094.11 RLN70390.1 - 0.27 11.6 4.2 0.2 12.0 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1925) Csm1_N PF18504.1 RLN70406.1 - 0.0088 16.4 4.1 0.028 14.7 4.0 2.1 1 1 0 1 1 1 1 Csm1 N-terminal domain Acetyltransf_4 PF13420.7 RLN70406.1 - 0.11 12.7 0.8 0.17 12.0 0.8 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TnpV PF14198.6 RLN70406.1 - 1 9.4 5.0 0.11 12.5 0.5 1.7 2 0 0 2 2 2 0 Transposon-encoded protein TnpV MbeD_MobD PF04899.12 RLN70406.1 - 4.4 7.5 9.6 4 7.6 5.9 2.9 2 1 0 2 2 2 0 MbeD/MobD like RRM_1 PF00076.22 RLN70407.1 - 0.00026 20.7 0.0 0.0004 20.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 RLN70408.1 - 0.00035 21.1 7.0 0.00035 21.1 7.0 2.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase ODR4-like PF14778.6 RLN70409.1 - 8e-38 130.3 0.0 1.8e-37 129.2 0.0 1.5 1 1 0 1 1 1 1 Olfactory receptor 4-like PLATZ PF04640.14 RLN70410.1 - 0.079 13.6 1.3 0.079 13.6 1.3 2.2 2 0 0 2 2 2 0 PLATZ transcription factor PLATZ PF04640.14 RLN70412.1 - 0.23 12.1 2.9 0.31 11.7 0.5 2.0 2 0 0 2 2 2 0 PLATZ transcription factor Ank_2 PF12796.7 RLN70413.1 - 5.2e-06 27.0 0.1 1.3e-05 25.7 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN70413.1 - 1.3e-05 25.3 0.1 8.9e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN70413.1 - 0.011 16.2 0.2 4.5 8.0 0.0 2.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 RLN70413.1 - 0.026 15.0 0.2 0.24 11.9 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeat Myotub-related PF06602.14 RLN70414.1 - 4.4e-105 351.5 0.0 1.7e-103 346.3 0.0 2.2 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 RLN70414.1 - 0.0084 15.7 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RLN70414.1 - 0.018 15.0 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 RLN70414.1 - 0.028 14.2 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain GCIP PF13324.6 RLN70414.1 - 1.3 8.6 10.5 3.1 7.3 10.5 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting 3-PAP PF12578.8 RLN70414.1 - 1.4 8.7 3.4 0.81 9.4 0.6 2.0 2 0 0 2 2 2 0 Myotubularin-associated protein Vfa1 PF08432.10 RLN70414.1 - 4.2 7.7 5.4 11 6.3 5.4 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Cyto_heme_lyase PF01265.17 RLN70415.1 - 2.1e-51 175.2 2.8 2.1e-51 175.2 2.8 2.6 2 1 0 2 2 2 1 Cytochrome c/c1 heme lyase TipAS PF07739.13 RLN70415.1 - 0.23 12.0 1.6 1.3 9.6 0.5 2.4 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain Ribosomal_S6e PF01092.19 RLN70416.1 - 5.9e-57 191.1 0.1 9.9e-57 190.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e zf-CCCH_4 PF18044.1 RLN70417.1 - 0.03 14.1 3.4 0.053 13.3 3.4 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger Med26 PF08711.11 RLN70417.1 - 0.036 14.1 0.3 0.036 14.1 0.3 2.1 2 0 0 2 2 2 0 TFIIS helical bundle-like domain zf-CCCH PF00642.24 RLN70417.1 - 0.049 13.6 2.1 0.11 12.5 2.1 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RLN70417.1 - 0.22 11.6 4.0 0.41 10.8 4.0 1.5 1 0 0 1 1 1 0 Zinc finger domain Ribosomal_60s PF00428.19 RLN70420.1 - 0.003 18.1 3.7 0.0048 17.5 3.7 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein CENP-B_dimeris PF09026.10 RLN70420.1 - 0.017 15.5 4.6 0.024 15.0 4.6 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Astro_capsid_p PF12226.8 RLN70420.1 - 0.15 11.2 2.8 0.18 10.9 2.8 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NOA36 PF06524.12 RLN70420.1 - 0.91 8.8 2.9 0.97 8.7 2.9 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 RLN70420.1 - 9.9 4.1 7.1 13 3.8 7.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi TauD PF02668.16 RLN70443.1 - 3.1e-38 132.1 0.2 4.4e-38 131.6 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 RLN70443.1 - 2.5e-11 44.0 0.5 4.6e-10 40.0 0.5 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 RLN70443.1 - 0.00016 20.9 0.0 0.012 14.7 0.0 2.1 2 0 0 2 2 2 2 CsiD IL17 PF06083.11 RLN70443.1 - 0.055 14.0 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Interleukin-17 HapK PF11639.8 RLN70443.1 - 0.1 13.1 0.1 0.28 11.7 0.1 1.8 1 0 0 1 1 1 0 REDY-like protein HapK Ank_2 PF12796.7 RLN70444.1 - 3.9e-27 94.7 0.3 2.4e-09 37.6 0.0 5.4 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN70444.1 - 1.6e-19 70.0 0.9 0.0013 19.2 0.1 8.0 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN70444.1 - 2.7e-17 62.6 8.1 0.00024 21.3 0.1 6.4 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN70444.1 - 1e-13 50.1 3.8 1.1 10.0 0.0 9.3 10 0 0 10 10 10 3 Ankyrin repeat Ank PF00023.30 RLN70444.1 - 1.2e-09 38.2 0.2 11 6.7 0.0 7.8 7 2 1 8 8 8 1 Ankyrin repeat DUF3655 PF12379.8 RLN70444.1 - 0.21 11.9 0.1 10 6.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3655) HEAT_2 PF13646.6 RLN70444.1 - 0.36 11.2 3.5 11 6.5 0.0 4.1 4 2 1 5 5 5 0 HEAT repeats RNA_pol PF00940.19 RLN70461.1 - 4.9e-72 243.1 0.2 3.9e-70 236.8 0.2 2.2 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 RLN70461.1 - 5.2e-54 183.9 2.0 6.3e-54 183.6 0.0 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal DUF1768 PF08719.11 RLN70461.1 - 0.16 12.2 6.8 0.025 14.8 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1768) Snapin_Pallidin PF14712.6 RLN70463.1 - 1.3e-15 57.6 0.0 1.5e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Snapin/Pallidin Guanylate_cyc PF00211.20 RLN70465.1 - 9.3e-23 80.8 0.0 1.1e-10 41.4 0.0 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain PH PF00169.29 RLN70465.1 - 4.5e-09 36.8 0.0 1.1e-08 35.6 0.0 1.6 1 0 0 1 1 1 1 PH domain FYVE PF01363.21 RLN70465.1 - 7e-09 35.7 13.0 7e-09 35.7 13.0 2.7 4 0 0 4 4 4 1 FYVE zinc finger AAA_16 PF13191.6 RLN70465.1 - 1.2e-05 25.8 0.6 0.00024 21.5 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain PH_9 PF15410.6 RLN70465.1 - 0.013 15.9 0.0 0.045 14.1 0.0 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain zf-rbx1 PF12678.7 RLN70466.1 - 1.1e-09 38.4 4.4 2.1e-09 37.5 4.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 RLN70466.1 - 4.6e-09 36.0 7.1 7.5e-09 35.3 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN70466.1 - 7.6e-09 35.8 6.5 1.3e-08 35.0 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RLN70466.1 - 2.5e-08 33.6 4.0 4.1e-08 33.0 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN70466.1 - 1.6e-06 27.8 5.9 3e-06 27.0 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RLN70466.1 - 0.00012 22.1 2.5 0.00026 21.0 2.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 RLN70466.1 - 0.00026 20.8 5.2 0.00047 20.0 5.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN70466.1 - 0.00029 20.7 3.9 0.00051 19.9 3.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 RLN70466.1 - 0.025 14.3 5.1 0.025 14.3 2.9 2.0 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 RLN70466.1 - 0.028 14.5 3.8 0.036 14.1 0.9 2.4 1 1 1 2 2 2 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 RLN70466.1 - 0.084 12.5 6.1 0.17 11.5 6.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 RLN70466.1 - 0.23 11.4 1.2 0.55 10.1 1.2 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein ARS2 PF04959.13 RLN70466.1 - 0.34 11.3 4.5 3.6 7.9 1.8 2.6 2 0 0 2 2 2 0 Arsenite-resistance protein 2 RINGv PF12906.7 RLN70466.1 - 0.95 9.6 6.6 1.8 8.7 6.6 1.5 1 0 0 1 1 1 0 RING-variant domain zf-P11 PF03854.14 RLN70466.1 - 1.1 9.0 3.5 1.9 8.2 3.5 1.3 1 0 0 1 1 1 0 P-11 zinc finger DNA_pol_lambd_f PF10391.9 RLN70467.1 - 0.04 13.8 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda CIA30 PF08547.12 RLN70467.1 - 0.075 13.0 0.0 0.084 12.9 0.0 1.1 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) Reprolysin_5 PF13688.6 RLN70469.1 - 0.00022 21.4 0.1 0.0047 17.1 0.0 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12 Peptidase_M6 PF05547.11 RLN70469.1 - 0.0034 15.8 1.0 0.0065 14.9 1.0 1.5 1 1 0 1 1 1 1 Immune inhibitor A peptidase M6 Reprolysin_4 PF13583.6 RLN70469.1 - 0.013 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 RLN70469.1 - 0.04 13.8 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 RLN70469.1 - 0.13 12.8 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like TPR_1 PF00515.28 RLN70470.1 - 1.6e-19 68.8 12.9 0.0052 16.6 0.1 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 RLN70470.1 - 8e-15 53.7 15.4 0.046 13.8 0.3 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 RLN70470.1 - 6.2e-09 35.4 9.8 0.022 14.9 0.1 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN70470.1 - 8.2e-09 35.0 12.1 0.00014 21.5 0.8 5.2 4 1 1 5 5 5 2 TPR repeat TPR_12 PF13424.6 RLN70470.1 - 1.5e-08 34.8 9.6 0.0003 21.0 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN70470.1 - 6.6e-07 29.9 14.1 0.25 12.0 0.1 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 RLN70470.1 - 5e-06 26.6 4.4 0.12 12.5 0.0 3.9 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN70470.1 - 4.3e-05 24.0 9.6 0.012 16.1 0.4 4.2 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN70470.1 - 0.00022 21.4 7.6 2.5 8.7 0.0 4.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN70470.1 - 0.0029 17.5 6.2 6.3 7.1 0.0 4.9 5 1 1 6 6 5 2 Tetratricopeptide repeat Desmo_N PF06771.11 RLN70470.1 - 0.041 14.3 0.0 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus MIT PF04212.18 RLN70470.1 - 0.043 13.9 6.4 4.8 7.3 0.0 4.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 RLN70470.1 - 0.05 13.7 2.1 4 7.6 0.2 3.8 3 1 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TetR PF13972.6 RLN70470.1 - 0.16 11.6 1.0 11 5.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial transcriptional repressor SNAP PF14938.6 RLN70470.1 - 0.59 9.5 7.7 0.18 11.2 1.8 2.2 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 RLN70470.1 - 0.75 9.7 0.1 0.75 9.7 0.1 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN70470.1 - 0.79 10.5 13.5 4.9 8.0 0.4 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat ABC_tran PF00005.27 RLN70471.1 - 3.3e-22 79.5 0.0 5.5e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN70471.1 - 0.0018 17.8 0.0 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 RLN70471.1 - 0.0042 15.9 0.1 0.0052 15.6 0.1 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class SbcCD_C PF13558.6 RLN70471.1 - 0.058 13.6 0.8 0.78 10.0 0.8 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Ccdc124 PF06244.12 RLN70474.1 - 4.3e-25 88.8 0.9 4.3e-25 88.8 0.9 3.0 2 2 1 3 3 3 1 Coiled-coil domain-containing protein 124 /Oxs1 Nexin_C PF08628.12 RLN70474.1 - 4.7 7.8 6.8 16 6.1 5.3 2.4 2 1 0 2 2 2 0 Sorting nexin C terminal DUF1754 PF08555.10 RLN70475.1 - 0.00068 20.4 2.0 0.00068 20.4 2.0 2.2 2 0 0 2 2 2 2 Eukaryotic family of unknown function (DUF1754) PAN_4 PF14295.6 RLN70476.1 - 6.6e-22 77.2 26.4 2.7e-09 36.8 2.9 5.1 5 0 0 5 5 5 3 PAN domain PAN_2 PF08276.11 RLN70476.1 - 2.9e-07 30.5 22.9 0.03 14.5 2.5 3.9 3 0 0 3 3 3 3 PAN-like domain CobT_C PF11775.8 RLN70476.1 - 0.0021 17.8 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT VWA domain YcaO_C PF18381.1 RLN70476.1 - 0.18 11.7 0.0 6.6 6.6 0.0 2.2 2 0 0 2 2 2 0 YcaO cyclodehydratase C-terminal domain PH_17 PF18012.1 RLN70476.1 - 0.21 11.3 3.2 42 4.0 0.1 3.5 3 0 0 3 3 3 0 PH domain DENN PF02141.21 RLN70477.1 - 3.5e-36 124.9 0.0 6.7e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain AalphaY_MDB PF04611.12 RLN70477.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region Rrn6 PF10214.9 RLN70478.1 - 0.81 8.1 3.5 1 7.8 3.5 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Nucleo_P87 PF07267.11 RLN70478.1 - 6.5 5.5 8.9 7.2 5.3 8.9 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Asparaginase PF00710.20 RLN70480.1 - 3e-57 193.3 0.0 4.3e-57 192.8 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 RLN70480.1 - 1.2e-28 99.6 0.1 2.2e-28 98.8 0.1 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Peptidase_M24 PF00557.24 RLN70481.1 - 9.9e-07 28.7 0.1 1.6e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 RLN70481.1 - 0.0023 18.6 0.0 0.0053 17.4 0.0 1.7 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Acetyltransf_1 PF00583.25 RLN70482.1 - 3.3e-15 56.3 0.0 5e-15 55.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RLN70482.1 - 3.5e-15 56.1 0.0 5.5e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN70482.1 - 2.3e-12 47.2 0.0 3.8e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN70482.1 - 3.5e-07 30.1 0.0 5.7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 RLN70482.1 - 8.1e-06 26.1 0.0 2.8e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 RLN70482.1 - 8.8e-05 23.2 0.1 0.00013 22.7 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 RLN70482.1 - 0.0063 16.6 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Mrr_cat PF04471.12 RLN70482.1 - 0.096 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease Acetyltransf_1 PF00583.25 RLN70483.1 - 7.8e-17 61.6 0.0 1.1e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RLN70483.1 - 4.2e-15 55.8 0.0 5.8e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN70483.1 - 2.4e-13 50.3 0.0 3.6e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 RLN70483.1 - 1.9e-07 31.4 0.0 2.6e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 RLN70483.1 - 5.2e-06 27.2 0.0 6.4e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN70483.1 - 4.1e-05 23.5 0.0 6.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 RLN70483.1 - 0.0017 18.5 0.0 0.005 16.9 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 RLN70483.1 - 0.01 15.9 0.2 0.043 13.9 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 RLN70483.1 - 0.073 13.1 0.0 0.2 11.7 0.0 1.7 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Acetyltransf_6 PF13480.7 RLN70483.1 - 0.075 13.2 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.6 RLN70483.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 RNA_pol PF00940.19 RLN70484.1 - 2e-71 241.1 0.1 1.2e-69 235.2 0.1 2.3 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 RLN70484.1 - 1.3e-53 182.6 0.7 2.7e-53 181.5 0.0 1.8 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal DUF1768 PF08719.11 RLN70484.1 - 6.7 6.9 7.3 0.44 10.8 1.4 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1768) Guanylate_cyc PF00211.20 RLN70486.1 - 2.1e-22 79.6 0.0 2.6e-10 40.2 0.1 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain PH PF00169.29 RLN70486.1 - 7.1e-10 39.3 0.0 1.7e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 PH domain FYVE PF01363.21 RLN70486.1 - 7e-09 35.7 13.0 7e-09 35.7 13.0 2.7 3 0 0 3 3 3 1 FYVE zinc finger AAA_16 PF13191.6 RLN70486.1 - 6.5e-05 23.4 0.0 0.00027 21.4 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain PH_9 PF15410.6 RLN70486.1 - 0.0045 17.3 0.0 0.015 15.7 0.0 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.6 RLN70487.1 - 2.1 8.7 5.4 4.5 7.7 5.4 1.6 1 0 0 1 1 1 0 Ring finger domain Snapin_Pallidin PF14712.6 RLN70488.1 - 4.8e-16 59.0 0.0 5.7e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Snapin/Pallidin DUF3138 PF11336.8 RLN70488.1 - 0.092 11.3 0.2 0.11 11.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) T3SS_needle_E PF08988.10 RLN70488.1 - 0.25 11.5 3.0 5 7.3 0.2 2.2 1 1 1 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Asparaginase_2 PF01112.18 RLN70502.1 - 1.4e-38 132.7 0.7 1.6e-15 57.0 0.1 3.0 3 0 0 3 3 3 3 Asparaginase dCMP_cyt_deam_1 PF00383.23 RLN70503.1 - 7.7e-19 67.4 0.0 9.6e-19 67.1 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 RLN70503.1 - 1.6e-16 60.3 0.0 2e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 RLN70503.1 - 0.00013 22.1 0.0 0.00035 20.7 0.0 1.6 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 RLN70503.1 - 0.00021 21.3 0.3 0.072 13.2 0.2 2.2 1 1 1 2 2 2 2 Bd3614-like deaminase NAD1 PF18778.1 RLN70503.1 - 0.003 17.7 0.0 0.0079 16.3 0.0 1.6 2 0 0 2 2 2 1 Novel AID APOBEC clade 1 NAD2 PF18782.1 RLN70503.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.4 2 0 0 2 2 2 0 Novel AID APOBEC clade 2 APOBEC2 PF18772.1 RLN70503.1 - 0.017 15.2 0.0 0.037 14.1 0.0 1.5 2 0 0 2 2 2 0 APOBEC2 APOBEC_N PF08210.11 RLN70503.1 - 0.046 13.6 0.0 0.069 13.0 0.0 1.5 1 1 0 1 1 1 0 APOBEC-like N-terminal domain APOBEC3 PF18771.1 RLN70503.1 - 0.18 11.9 0.0 0.27 11.3 0.0 1.2 1 0 0 1 1 1 0 APOBEC3 APOBEC4 PF18775.1 RLN70503.1 - 0.22 11.7 0.1 1.8 8.8 0.1 2.0 2 0 0 2 2 2 0 APOBEC4 Amdase PF17645.1 RLN70507.1 - 0.097 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Arylmalonate decarboxylase SpoIIIAH PF12685.7 RLN70509.1 - 0.014 15.2 0.8 0.025 14.4 0.8 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein OSTbeta PF15048.6 RLN70509.1 - 0.18 12.0 2.1 0.31 11.2 0.1 2.3 3 0 0 3 3 3 0 Organic solute transporter subunit beta protein CLN3 PF02487.17 RLN70509.1 - 0.25 10.4 0.7 0.37 9.8 0.7 1.3 1 1 0 1 1 1 0 CLN3 protein Conotoxin PF02950.17 RLN70509.1 - 0.69 11.0 3.3 0.77 10.8 0.1 2.4 2 0 0 2 2 2 0 Conotoxin Glyco_hydro_3 PF00933.21 RLN70510.1 - 1.6e-57 195.3 0.0 3.3e-57 194.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN70510.1 - 5.6e-34 117.9 0.0 1e-33 117.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RLN70510.1 - 1.2e-11 44.6 0.1 2.2e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PKD PF00801.20 RLN70510.1 - 0.004 17.0 0.2 0.039 13.8 0.1 2.4 2 0 0 2 2 2 1 PKD domain DUF2336 PF10098.9 RLN70510.1 - 0.065 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) DUF11 PF01345.18 RLN70510.1 - 0.19 12.0 1.4 1.4 9.2 0.5 2.9 2 1 0 2 2 2 0 Domain of unknown function DUF11 ALS_ss_C PF10369.9 RLN70511.1 - 1.6e-24 85.9 0.1 4.8e-24 84.4 0.0 1.8 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 RLN70511.1 - 2.2e-10 40.1 0.2 6.9e-10 38.5 0.1 1.9 2 0 0 2 2 2 1 ACT domain ACT_5 PF13710.6 RLN70511.1 - 2.5e-05 24.0 0.0 5.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 ACT domain MA3 PF02847.17 RLN70511.1 - 0.038 14.0 0.1 0.066 13.2 0.1 1.5 1 1 0 1 1 1 0 MA3 domain Peptidase_S10 PF00450.22 RLN70512.1 - 5.4e-97 325.8 0.0 1e-96 324.9 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase Tim17 PF02466.19 RLN70513.1 - 2.3e-05 24.7 1.9 4.3e-05 23.8 1.9 1.5 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pkinase_Tyr PF07714.17 RLN70525.1 - 4.9e-41 140.7 0.0 3.3e-36 124.9 0.0 3.2 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 RLN70525.1 - 6.7e-39 133.8 0.0 8.7e-35 120.4 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 RLN70525.1 - 3.1e-05 22.9 0.0 5.9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN70525.1 - 0.11 12.4 2.9 0.43 10.5 0.1 3.0 3 1 0 3 3 3 0 Phosphotransferase enzyme family HEAT_EZ PF13513.6 RLN70534.1 - 4.1 8.0 5.0 53 4.5 0.0 3.6 4 0 0 4 4 4 0 HEAT-like repeat Pepdidase_M14_N PF18027.1 RLN70535.1 - 1.1e-05 25.8 1.3 3.1e-05 24.3 1.0 1.9 2 0 0 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 RLN70535.1 - 0.025 14.4 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Zinc carboxypeptidase TPR_2 PF07719.17 RLN70536.1 - 6.6e-21 72.7 11.8 0.014 15.5 0.0 8.8 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 RLN70536.1 - 1.8e-17 62.3 8.2 0.041 13.7 0.0 8.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 RLN70536.1 - 1.6e-15 55.9 4.9 0.034 14.4 0.0 8.5 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 RLN70536.1 - 5.9e-14 51.6 14.4 0.21 12.5 0.1 7.0 4 2 2 7 7 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 RLN70536.1 - 1.4e-11 43.9 11.0 0.00019 21.0 0.0 6.6 8 0 0 8 8 8 2 TPR repeat TPR_9 PF13371.6 RLN70536.1 - 8.5e-11 41.9 12.4 0.0024 18.0 0.4 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 RLN70536.1 - 4.4e-09 36.7 5.2 0.025 15.1 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 RLN70536.1 - 8.3e-09 36.0 12.9 0.0073 16.9 0.2 5.3 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 RLN70536.1 - 0.0002 21.6 18.9 0.14 12.5 2.3 6.3 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN70536.1 - 0.00091 19.1 8.9 0.3 11.2 0.2 6.1 6 2 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN70536.1 - 0.005 17.1 5.5 1.3 9.5 0.0 4.8 6 0 0 6 6 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN70536.1 - 0.033 14.4 9.5 0.43 10.8 0.1 3.9 1 1 5 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.6 RLN70536.1 - 0.06 13.8 2.3 1.8 9.0 0.2 3.2 2 1 0 3 3 3 0 Alkyl sulfatase dimerisation ECSIT_C PF14784.6 RLN70536.1 - 0.12 12.7 0.8 1.2 9.5 0.0 2.2 1 1 0 2 2 2 0 C-terminal domain of the ECSIT protein DUF3856 PF12968.7 RLN70536.1 - 0.21 11.7 3.8 16 5.6 0.8 3.6 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) Vma12 PF11712.8 RLN70536.1 - 3.3 7.8 5.9 14 5.8 5.7 2.0 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Dynein_light PF01221.18 RLN70537.1 - 6e-28 97.0 1.6 6.6e-28 96.9 1.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Rep_fac-A_C PF08646.10 RLN70539.1 - 7.2e-42 142.6 4.3 1.7e-41 141.4 4.3 1.7 1 0 0 1 1 1 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 RLN70539.1 - 8.5e-32 109.0 0.6 1.8e-30 104.8 0.7 2.4 2 0 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 RLN70539.1 - 6e-14 51.8 0.9 3.9e-08 33.2 0.0 3.8 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain Rep-A_N PF04057.12 RLN70539.1 - 0.0011 19.0 0.4 0.0063 16.5 0.1 2.4 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti_2 PF13742.6 RLN70539.1 - 0.085 13.1 0.0 1.8 8.8 0.0 2.9 3 0 0 3 3 3 0 OB-fold nucleic acid binding domain Zn_Tnp_IS1595 PF12760.7 RLN70539.1 - 0.13 12.2 1.9 0.3 11.1 1.9 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DZR PF12773.7 RLN70539.1 - 0.54 10.3 4.8 1.2 9.3 4.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 RLN70539.1 - 0.85 9.6 10.9 0.31 11.1 7.8 1.8 2 0 0 2 2 2 0 zinc-ribbons PADR1 PF08063.12 RLN70539.1 - 2.1 8.2 8.4 6.1 6.7 8.4 1.7 1 0 0 1 1 1 0 PADR1 (NUC008) domain zf_UBZ PF18439.1 RLN70539.1 - 8 6.1 6.2 46 3.7 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DIM1 PF02966.16 RLN70540.1 - 7e-17 61.5 0.6 1.4e-12 47.5 0.2 2.1 1 1 1 2 2 2 2 Mitosis protein DIM1 TPR_2 PF07719.17 RLN70541.1 - 2.1e-08 33.7 12.0 3.3e-06 26.8 3.2 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN70541.1 - 5.1e-08 32.4 7.2 4.1e-05 23.2 2.6 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN70541.1 - 7e-07 28.8 5.6 0.00012 21.6 0.4 2.9 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 RLN70541.1 - 0.00012 22.0 2.7 0.00012 22.0 0.5 2.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 RLN70541.1 - 0.00026 20.3 0.1 0.0056 15.9 0.2 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 RLN70541.1 - 0.04 13.4 0.7 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 SHNi-TPR TPR_9 PF13371.6 RLN70541.1 - 0.089 12.9 2.2 2 8.6 1.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN70541.1 - 0.16 12.7 10.3 0.33 11.6 1.2 2.5 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN70541.1 - 0.19 12.6 4.7 0.33 11.9 0.8 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN70541.1 - 0.22 11.8 7.6 0.3 11.4 3.2 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Histone PF00125.24 RLN70542.1 - 9.7e-41 139.2 0.7 1e-40 139.1 0.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 RLN70542.1 - 0.00034 20.7 0.1 0.00044 20.3 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 RLN70542.1 - 0.00035 20.9 0.0 0.00045 20.5 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 RLN70542.1 - 0.0086 16.3 0.1 0.015 15.6 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 RLN70542.1 - 0.017 15.2 0.0 0.02 15.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 RLN70543.1 - 3.8e-08 33.4 0.0 5.6e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 RLN70543.1 - 0.00038 20.8 0.0 0.00059 20.2 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein TAF PF02969.17 RLN70543.1 - 0.00065 19.8 0.1 0.00096 19.3 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 RLN70543.1 - 0.0085 16.5 0.3 0.013 15.8 0.1 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RLN70543.1 - 0.0088 16.3 0.1 0.014 15.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 RLN70543.1 - 0.041 14.0 0.0 0.072 13.2 0.0 1.4 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 RLN70543.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated WW PF00397.26 RLN70545.1 - 3.5e-32 110.1 32.1 9.6e-08 32.0 6.6 4.3 4 0 0 4 4 4 4 WW domain IQ PF00612.27 RLN70545.1 - 5.8e-05 22.5 14.7 0.16 11.8 1.2 5.2 6 0 0 6 6 6 3 IQ calmodulin-binding motif ATPase-cat_bd PF12156.8 RLN70545.1 - 0.00084 20.0 1.9 1.1 10.1 0.0 3.4 3 0 0 3 3 3 2 Putative metal-binding domain of cation transport ATPase DUF4585 PF15232.6 RLN70545.1 - 0.02 14.9 2.1 2.1 8.5 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4585) Hydrolase_2 PF07486.12 RLN70545.1 - 0.31 11.9 14.0 0.35 11.7 0.1 3.8 2 1 2 4 4 4 0 Cell Wall Hydrolase Carn_acyltransf PF00755.20 RLN70546.1 - 1.7e-166 555.3 0.1 1.9e-166 555.2 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Vps54 PF07928.12 RLN70547.1 - 2e-20 73.6 8.1 2.7e-12 47.3 0.2 3.9 3 1 1 4 4 4 2 Vps54-like protein Vps54_N PF10475.9 RLN70547.1 - 8e-06 25.3 0.1 8e-06 25.3 0.1 3.3 5 0 0 5 5 5 1 Vacuolar-sorting protein 54, of GARP complex 4HB_MCP_1 PF12729.7 RLN70547.1 - 0.019 14.5 0.2 0.33 10.5 0.0 2.6 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction G-alpha PF00503.20 RLN70547.1 - 0.15 11.2 2.7 6.3 5.8 0.0 2.9 2 1 1 3 3 3 0 G-protein alpha subunit Stirrup PF09061.6 RLN70547.1 - 0.28 11.4 5.1 24 5.2 0.1 3.7 2 1 1 3 3 3 0 Stirrup Lipase_3 PF01764.25 RLN70548.1 - 2.1e-11 43.9 0.0 4.7e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DFP PF04127.15 RLN70548.1 - 1e-05 25.4 0.4 0.00046 20.1 0.1 3.1 2 1 1 3 3 3 1 DNA / pantothenate metabolism flavoprotein PE-PPE PF08237.11 RLN70548.1 - 0.0026 17.3 0.0 0.0059 16.2 0.0 1.5 1 0 0 1 1 1 1 PE-PPE domain Thioesterase PF00975.20 RLN70548.1 - 0.0055 16.8 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 RLN70548.1 - 0.016 15.8 0.1 0.016 15.8 0.1 2.7 4 0 0 4 4 4 0 Alpha/beta hydrolase family Thr_dehydrat_C PF00585.18 RLN70548.1 - 0.13 12.0 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase WD40 PF00400.32 RLN70549.1 - 1.5e-18 66.8 6.3 2.3e-06 28.2 0.1 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Lgl_C PF08596.10 RLN70549.1 - 0.067 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal Pex2_Pex12 PF04757.14 RLN70550.1 - 3.9e-18 65.9 0.0 5.5e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 RLN70550.1 - 0.00081 19.3 6.1 0.0021 18.0 6.1 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RLN70550.1 - 0.0051 16.6 4.5 0.01 15.7 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN70550.1 - 0.0057 17.0 4.2 0.0098 16.2 4.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RLN70550.1 - 0.0092 15.8 4.8 0.016 15.0 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN70550.1 - 0.017 14.9 4.6 0.028 14.3 4.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN70550.1 - 0.02 14.7 4.2 0.034 14.0 4.2 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 RLN70550.1 - 0.051 13.6 2.9 0.1 12.6 2.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger SBDS_C PF09377.10 RLN70551.1 - 2.3e-31 108.2 0.1 5.7e-31 106.9 0.1 1.7 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 RLN70551.1 - 3.2e-29 100.8 1.1 5.6e-29 100.1 1.1 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Ribosomal_60s PF00428.19 RLN70551.1 - 0.081 13.5 0.7 0.081 13.5 0.7 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein HydF_dimer PF18128.1 RLN70551.1 - 0.12 12.4 0.0 9.4 6.4 0.0 2.5 1 1 1 2 2 2 0 Hydrogen maturase F dimerization domain ANAPC3 PF12895.7 RLN70552.1 - 0.012 15.8 0.2 0.028 14.7 0.2 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4259 PF14078.6 RLN70552.1 - 1.4 9.7 4.3 1.8 9.3 2.9 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4259) DUF1778 PF08681.11 RLN70552.1 - 3.9 7.5 7.7 17 5.4 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1778) Lactamase_B_2 PF12706.7 RLN70553.1 - 1e-08 35.0 2.3 1.8e-08 34.1 2.3 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 RLN70553.1 - 0.05 13.6 3.2 0.052 13.5 0.5 2.3 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily Atg8 PF02991.16 RLN70553.1 - 0.14 12.4 0.0 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 Autophagy protein Atg8 ubiquitin like PDEase_II PF02112.15 RLN70553.1 - 0.16 11.0 3.0 0.08 12.0 0.7 1.5 2 0 0 2 2 2 0 cAMP phosphodiesterases class-II MFS_1 PF07690.16 RLN70554.1 - 2.3e-09 36.7 28.5 0.0001 21.3 14.4 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily Peptidase_U4 PF03419.13 RLN70554.1 - 0.03 13.6 14.2 0.025 13.9 2.6 2.3 2 0 0 2 2 2 0 Sporulation factor SpoIIGA DUF5337 PF17272.2 RLN70554.1 - 0.17 11.7 12.0 2 8.3 1.7 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5337) Enkurin PF13864.6 RLN70555.1 - 8.3e-24 83.9 0.5 8.3e-24 83.9 0.5 1.9 2 0 0 2 2 2 1 Calmodulin-binding eIF-3c_N PF05470.12 RLN70556.1 - 9.2e-154 513.0 38.1 7.4e-150 500.1 38.1 3.0 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2204 PF09970.9 RLN70556.1 - 0.0071 16.0 2.6 0.019 14.6 0.0 2.6 3 0 0 3 3 3 1 Nucleotidyl transferase of unknown function (DUF2204) Dsh_C PF12316.8 RLN70556.1 - 4.4 7.7 23.2 3.1 8.2 0.2 2.6 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal AAA PF00004.29 RLN70560.1 - 3.2e-18 66.4 0.0 1.1e-17 64.7 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RLN70560.1 - 1.6e-06 28.2 0.0 4.8e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RLN70560.1 - 3.3e-06 27.6 1.8 1.5e-05 25.4 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 RLN70560.1 - 0.00025 21.4 0.2 0.00084 19.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain Cpn60_TCP1 PF00118.24 RLN70560.1 - 0.00058 18.6 0.1 0.00094 17.9 0.1 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF815 PF05673.13 RLN70560.1 - 0.0012 18.1 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 RLN70560.1 - 0.0016 18.2 0.0 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RLN70560.1 - 0.002 18.3 0.0 0.022 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 RLN70560.1 - 0.0051 17.1 0.0 0.1 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 RLN70560.1 - 0.0058 16.4 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RLN70560.1 - 0.011 15.4 0.1 0.025 14.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 RLN70560.1 - 0.019 14.9 0.6 0.7 9.8 0.1 2.4 2 0 0 2 2 2 0 NTPase AAA_7 PF12775.7 RLN70560.1 - 0.02 14.4 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Bac_DnaA PF00308.18 RLN70560.1 - 0.059 13.2 0.0 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_19 PF13245.6 RLN70560.1 - 0.06 13.7 0.1 0.17 12.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RLN70560.1 - 0.071 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 RLN70560.1 - 0.085 13.3 0.0 0.26 11.7 0.0 1.9 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 RLN70560.1 - 0.091 13.3 0.0 0.27 11.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_6 PF12774.7 RLN70560.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 RLN70560.1 - 0.11 13.1 0.0 0.36 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 RLN70560.1 - 0.11 12.5 0.0 0.37 10.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 RLN70560.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 RLN70560.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PPV_E1_C PF00519.17 RLN70560.1 - 0.16 10.8 0.1 0.26 10.1 0.1 1.3 1 0 0 1 1 1 0 Papillomavirus helicase Cpn60_TCP1 PF00118.24 RLN70561.1 - 3.9e-135 451.3 7.5 4.8e-135 450.9 7.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1132 PF06575.12 RLN70561.1 - 0.14 12.6 0.1 0.38 11.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) Elicitin PF00964.17 RLN70562.1 - 2.1e-15 56.6 8.0 5.3e-15 55.3 8.0 1.7 1 0 0 1 1 1 1 Elicitin Spore_YtfJ PF09579.10 RLN70562.1 - 0.07 13.3 0.1 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) BUD22 PF09073.10 RLN70562.1 - 1 8.6 8.1 1.2 8.4 8.1 1.1 1 0 0 1 1 1 0 BUD22 SWI-SNF_Ssr4 PF08549.10 RLN70562.1 - 4.2 5.9 7.9 4.5 5.8 7.9 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Pkinase PF00069.25 RLN70563.1 - 4.7e-55 186.8 0.0 6.6e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN70563.1 - 4.6e-48 163.8 0.0 6.1e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EphA2_TM PF14575.6 RLN70563.1 - 5.2e-05 24.0 0.0 9.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 RLN70563.1 - 0.00035 20.9 0.0 0.00056 20.2 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator APH PF01636.23 RLN70563.1 - 0.0033 17.4 0.1 0.0065 16.4 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family TMIE PF16038.5 RLN70563.1 - 0.0051 16.6 0.8 0.011 15.5 0.8 1.5 1 0 0 1 1 1 1 TMIE protein GRP PF07172.11 RLN70563.1 - 0.02 15.6 0.2 0.043 14.5 0.2 1.5 1 0 0 1 1 1 0 Glycine rich protein family Rhabdo_glycop PF00974.18 RLN70563.1 - 0.027 12.9 0.3 0.046 12.2 0.3 1.3 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Mucin PF01456.17 RLN70563.1 - 0.044 13.8 0.3 0.082 12.9 0.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Orthoreo_P10 PF07204.11 RLN70563.1 - 0.05 13.6 0.3 0.097 12.6 0.3 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 TMEM51 PF15345.6 RLN70563.1 - 0.059 13.2 0.0 0.087 12.7 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Haspin_kinase PF12330.8 RLN70563.1 - 0.071 12.0 0.0 0.15 11.0 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Comm PF15957.5 RLN70563.1 - 0.071 13.5 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Commissureless Metallophos PF00149.28 RLN70568.1 - 4.9e-13 50.0 0.0 7.9e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RLN70568.1 - 0.00047 20.4 0.1 0.022 15.0 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain DUF5071 PF16804.5 RLN70569.1 - 0.033 14.4 0.0 0.064 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5071) SpoU_sub_bind PF08032.12 RLN70570.1 - 2.4e-06 27.7 0.1 7.4e-06 26.1 0.1 1.7 1 1 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding SpoU_methylase PF00588.19 RLN70570.1 - 0.045 13.9 0.0 0.076 13.2 0.0 1.3 1 0 0 1 1 1 0 SpoU rRNA Methylase family EF-hand_1 PF00036.32 RLN70571.1 - 2.6e-13 48.5 0.6 2.7e-06 26.5 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN70571.1 - 3.2e-12 45.3 0.1 0.00014 21.5 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RLN70571.1 - 4.1e-11 41.9 3.4 4e-07 29.2 0.0 2.8 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 RLN70571.1 - 5.2e-11 42.8 0.6 1.4e-10 41.4 0.6 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RLN70571.1 - 3.2e-07 30.1 0.6 0.0064 16.3 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair MukE PF04288.13 RLN70571.1 - 0.014 14.3 0.4 0.025 13.5 0.4 1.3 1 0 0 1 1 1 0 MukE-like family SPARC_Ca_bdg PF10591.9 RLN70571.1 - 0.044 14.1 0.1 0.13 12.6 0.1 1.8 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region V-ATPase_H_C PF11698.8 RLN70571.1 - 0.098 12.8 0.8 0.23 11.6 0.8 1.5 1 0 0 1 1 1 0 V-ATPase subunit H Flavi_M PF01004.19 RLN70571.1 - 0.16 11.7 0.2 0.54 10.1 0.0 1.9 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M HEAT PF02985.22 RLN70572.1 - 0.041 14.2 6.3 12 6.5 0.2 4.5 4 0 0 4 4 4 0 HEAT repeat IFRD PF05004.13 RLN70572.1 - 0.047 12.8 0.2 0.33 10.0 0.0 2.3 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Beach PF02138.18 RLN70573.1 - 8.9e-116 386.1 0.6 8.9e-116 386.1 0.6 1.5 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 RLN70573.1 - 8.8e-21 73.9 0.0 4.7e-20 71.5 0.0 2.3 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.32 RLN70573.1 - 0.00011 22.9 3.4 0.13 13.2 0.2 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Laminin_G_3 PF13385.6 RLN70573.1 - 0.0003 21.0 0.0 0.0014 18.8 0.0 2.1 1 1 1 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF4704 PF15787.5 RLN70573.1 - 0.021 14.1 9.5 0.007 15.6 1.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4704) Anoctamin PF04547.12 RLN70574.1 - 2.8e-65 220.9 15.5 3.7e-65 220.5 15.5 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel EF-hand_6 PF13405.6 RLN70574.1 - 5.4e-06 25.9 0.0 0.0019 18.0 0.0 3.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 RLN70574.1 - 0.00016 21.0 0.0 0.074 12.6 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RLN70574.1 - 0.00021 21.7 0.0 0.0018 18.7 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 RLN70574.1 - 0.0041 16.9 0.0 0.088 12.7 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair MAJIN PF15077.6 RLN70575.1 - 0.13 12.1 2.4 0.18 11.6 2.4 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein PTR2 PF00854.21 RLN70576.1 - 2.4e-75 253.9 5.6 5.1e-75 252.8 5.6 1.5 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 RLN70576.1 - 1.1e-05 24.5 11.6 1.1e-05 24.5 11.6 3.9 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF2755 PF10954.8 RLN70576.1 - 1.2 9.1 4.4 0.81 9.6 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2755) RIO1 PF01163.22 RLN70580.1 - 4.7e-38 130.7 0.0 3e-29 102.0 0.0 2.2 1 1 1 2 2 2 2 RIO1 family Pkinase PF00069.25 RLN70580.1 - 2.3e-06 27.2 0.0 3.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN70580.1 - 0.075 12.3 0.2 0.26 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase VWA_3 PF13768.6 RLN70580.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain CCDC50_N PF15295.6 RLN70580.1 - 0.16 12.1 4.1 0.059 13.5 1.1 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus Ferric_reduct PF01794.19 RLN70581.1 - 1.2e-17 64.1 12.9 1.2e-17 64.1 12.9 3.0 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 RLN70581.1 - 6.2e-15 55.6 0.0 1.3e-14 54.6 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 RLN70581.1 - 4.5e-10 39.6 0.0 9.3e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain WTF PF03303.13 RLN70581.1 - 0.16 11.7 0.0 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 WTF protein Ank_4 PF13637.6 RLN70582.1 - 9.9e-32 108.9 12.2 1.5e-05 25.5 0.0 9.9 7 4 1 9 9 9 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN70582.1 - 7.1e-30 103.4 3.3 6.4e-07 29.9 0.0 6.4 2 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN70582.1 - 8.4e-27 92.9 21.2 0.00093 19.5 0.0 12.1 4 1 9 13 13 13 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN70582.1 - 4.1e-14 51.3 4.0 8.4 7.3 0.0 13.1 12 3 3 15 15 15 1 Ankyrin repeat Ank PF00023.30 RLN70582.1 - 6.7e-05 23.2 0.2 1.7e+02 2.9 0.0 7.7 7 2 2 9 9 9 0 Ankyrin repeat DUF3322 PF11795.8 RLN70582.1 - 0.00021 21.3 0.2 1.7 8.6 0.0 4.1 4 0 0 4 4 4 2 Uncharacterized protein conserved in bacteria N-term (DUF3322) VbhA PF18495.1 RLN70582.1 - 0.0098 15.7 0.7 20 5.1 0.0 4.2 4 0 0 4 4 4 1 Antitoxin VbhA DUF1979 PF09322.10 RLN70582.1 - 0.063 13.2 0.5 18 5.3 0.1 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1979) Aa_trans PF01490.18 RLN70583.1 - 2e-38 132.2 28.7 3.1e-38 131.6 28.7 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Evr1_Alr PF04777.13 RLN70587.1 - 1.5e-08 35.0 0.1 1.7e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 Erv1 / Alr family DUF4267 PF14087.6 RLN70589.1 - 0.025 14.6 0.0 3.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) GFO_IDH_MocA PF01408.22 RLN70609.1 - 2.4e-21 76.8 0.0 3.5e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 RLN70609.1 - 9.4e-07 28.9 0.0 3.4e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 RLN70609.1 - 0.0012 19.5 0.0 0.002 18.7 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Aconitase_C PF00694.19 RLN70610.1 - 3.9e-06 27.2 0.0 1.5e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 Aconitase C-terminal domain FYVE PF01363.21 RLN70611.1 - 6.8e-12 45.4 10.8 1.6e-11 44.2 10.8 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN70611.1 - 0.0045 17.2 5.5 0.009 16.2 5.5 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger CCDC144C PF14915.6 RLN70611.1 - 1.2 8.2 6.5 0.039 13.1 0.5 1.4 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region Pkinase_Tyr PF07714.17 RLN70624.1 - 8.4e-41 140.0 0.0 1.4e-40 139.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN70624.1 - 8.2e-32 110.6 0.0 2.4e-31 109.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 RLN70624.1 - 0.014 14.7 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 RLN70625.1 - 6.6e-43 146.9 0.0 9.3e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN70625.1 - 7.5e-32 110.7 0.0 1.1e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN70626.1 - 1.4e-23 83.5 0.0 1.5e-23 83.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN70626.1 - 1.8e-21 76.7 0.0 2.2e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 RLN70626.1 - 0.088 11.7 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Exo_endo_phos_2 PF14529.6 RLN70632.1 - 4.3e-05 23.3 0.0 0.0001 22.1 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RLN70632.1 - 0.00091 18.8 0.0 0.0017 17.9 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glycos_transf_2 PF00535.26 RLN70649.1 - 1.1e-25 90.4 0.1 1.4e-25 90.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 RLN70649.1 - 1.9e-11 44.3 0.1 2.6e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 RLN70649.1 - 2.6e-07 30.4 0.0 3.6e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 SBD_N PF07005.11 RLN70649.1 - 0.00017 21.4 0.2 0.0003 20.6 0.2 1.3 1 0 0 1 1 1 1 Sugar-binding N-terminal domain Put_Phosphatase PF06888.12 RLN70650.1 - 1.7e-134 446.5 0.0 2.4e-54 184.2 0.0 5.0 3 2 1 4 4 4 4 Putative Phosphatase HAD PF12710.7 RLN70650.1 - 2.8e-19 70.3 1.2 6.1e-05 23.5 0.1 3.9 3 2 0 3 3 3 3 haloacid dehalogenase-like hydrolase RE_SinI PF09570.10 RLN70650.1 - 0.049 12.9 0.1 5.4 6.2 0.0 2.8 2 1 0 2 2 2 0 SinI restriction endonuclease Ank_2 PF12796.7 RLN70652.1 - 1.3e-40 137.8 0.7 1.2e-12 48.2 0.0 6.3 2 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN70652.1 - 1.6e-40 132.4 2.1 1.1e-05 25.4 0.0 9.5 8 1 1 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 RLN70652.1 - 9.6e-34 115.3 0.9 3.5e-10 40.2 0.0 8.5 4 1 4 8 8 8 6 Ankyrin repeats (many copies) TIR_2 PF13676.6 RLN70652.1 - 6.5e-32 110.6 0.0 1.8e-17 64.0 0.0 2.6 2 0 0 2 2 2 2 TIR domain Ank PF00023.30 RLN70652.1 - 6.9e-32 108.5 5.3 7.1e-05 23.1 0.0 8.6 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 RLN70652.1 - 3.9e-30 103.5 5.5 8.8e-07 29.1 0.0 6.8 4 1 2 6 6 6 6 Ankyrin repeats (many copies) TIR PF01582.20 RLN70652.1 - 7.4e-09 35.7 0.0 0.0016 18.2 0.0 2.9 3 0 0 3 3 3 2 TIR domain DUF1863 PF08937.11 RLN70652.1 - 4.5e-06 27.0 0.0 0.059 13.7 0.0 2.9 2 1 0 2 2 2 2 MTH538 TIR-like domain (DUF1863) DUF3810 PF12725.7 RLN70652.1 - 0.044 13.1 1.0 0.088 12.1 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) AMP-binding PF00501.28 RLN70653.1 - 1e-41 142.9 0.0 2.5e-41 141.7 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN70653.1 - 5.5e-06 27.3 0.0 1.2e-05 26.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain EF-hand_7 PF13499.6 RLN70660.1 - 3.3e-31 107.5 1.6 3.3e-12 46.7 0.0 5.0 5 0 0 5 5 4 3 EF-hand domain pair EF-hand_1 PF00036.32 RLN70660.1 - 3.6e-23 79.3 10.8 0.00011 21.5 0.1 5.9 6 0 0 6 6 5 5 EF hand EF-hand_6 PF13405.6 RLN70660.1 - 9.2e-21 72.0 9.2 0.00029 20.5 0.2 6.2 6 0 0 6 6 5 5 EF-hand domain EF-hand_8 PF13833.6 RLN70660.1 - 1e-18 66.9 8.4 2e-07 30.7 0.0 5.0 4 1 1 5 5 5 3 EF-hand domain pair Ank_2 PF12796.7 RLN70660.1 - 7.7e-16 58.5 1.6 0.00033 21.2 0.0 6.0 2 2 5 7 7 7 6 Ankyrin repeats (3 copies) WW PF00397.26 RLN70660.1 - 2.9e-14 52.8 5.7 6.8e-08 32.5 0.2 3.0 2 0 0 2 2 2 2 WW domain EF-hand_5 PF13202.6 RLN70660.1 - 8.3e-14 50.4 11.7 0.0035 16.8 0.1 5.9 6 0 0 6 6 5 4 EF hand Ank_4 PF13637.6 RLN70660.1 - 5.8e-07 29.9 5.7 0.0011 19.5 0.0 5.9 5 2 1 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN70660.1 - 2.1e-05 24.7 7.6 0.46 10.9 0.0 6.7 7 2 1 8 8 7 3 Ankyrin repeats (many copies) SPARC_Ca_bdg PF10591.9 RLN70660.1 - 3.2e-05 24.2 3.3 0.0026 18.1 0.7 4.0 3 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 RLN70660.1 - 0.00066 19.5 2.7 2 8.3 0.1 3.9 4 0 0 4 4 4 1 EF hand WW_FCH_linker PF16623.5 RLN70660.1 - 0.058 14.2 0.8 0.16 12.7 0.8 1.7 1 0 0 1 1 1 0 Unstructured linker region between on GAS7 protein Glyco_hyd_101C PF17451.2 RLN70660.1 - 0.12 12.7 2.2 0.88 9.9 0.0 2.9 3 0 0 3 3 2 0 Glycosyl hydrolase 101 beta sandwich domain Ank_3 PF13606.6 RLN70660.1 - 1.9 9.3 18.1 8.5 7.3 0.0 7.7 10 0 0 10 10 6 0 Ankyrin repeat MPM1 PF17234.2 RLN70660.1 - 2.3 8.4 4.8 2.7 8.2 2.9 2.1 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Pkinase_Tyr PF07714.17 RLN70661.1 - 6.9e-58 196.0 0.0 8.2e-58 195.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN70661.1 - 4.1e-57 193.6 0.0 5e-57 193.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 RLN70661.1 - 0.0001 21.2 0.0 0.00012 21.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN70661.1 - 0.00027 20.9 0.1 0.038 13.9 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 RLN70661.1 - 0.01 15.2 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 RLN70661.1 - 0.049 13.0 0.0 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RLN70661.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kinesin PF00225.23 RLN70662.1 - 1.3e-117 392.4 0.1 2.7e-117 391.4 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN70662.1 - 3.9e-27 95.0 0.0 2.4e-26 92.5 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding AAA_22 PF13401.6 RLN70662.1 - 0.13 12.5 7.3 0.97 9.7 0.0 4.1 4 1 0 4 4 4 0 AAA domain SET PF00856.28 RLN70663.1 - 1.9e-12 47.9 0.0 4.2e-12 46.8 0.0 1.6 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 RLN70663.1 - 2.9e-10 40.1 12.9 2.9e-10 40.1 12.9 3.1 3 0 0 3 3 3 1 MYND finger HALZ PF02183.18 RLN70664.1 - 0.0022 18.2 1.2 0.0043 17.2 1.2 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper YabA PF06156.13 RLN70664.1 - 0.16 12.6 0.8 0.36 11.5 0.8 1.6 1 0 0 1 1 1 0 Initiation control protein YabA DRY_EERY PF09750.9 RLN70664.1 - 2.4 8.4 5.7 8.4 6.7 5.7 1.9 1 1 0 1 1 1 0 Alternative splicing regulator Ribosomal_L18A PF01775.17 RLN70665.1 - 1e-20 74.0 0.0 1.9e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A MIF PF01187.18 RLN70665.1 - 1e-16 61.2 0.1 4.7e-16 59.1 0.1 1.8 1 1 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 RLN70665.1 - 2.3e-06 27.5 0.1 9.7e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 Tautomerase enzyme Tautomerase_2 PF14552.6 RLN70665.1 - 0.022 14.8 0.0 1.8 8.7 0.0 2.3 1 1 0 2 2 2 0 Tautomerase enzyme SET PF00856.28 RLN70666.1 - 3.2e-12 47.2 0.0 9.1e-07 29.4 0.0 2.6 2 0 0 2 2 2 2 SET domain Rubis-subs-bind PF09273.11 RLN70666.1 - 2.1e-08 34.9 1.3 2.1e-08 34.9 1.3 2.6 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding DUF4913 PF16259.5 RLN70666.1 - 0.1 12.7 1.6 0.29 11.2 1.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4913) TPR_18 PF13512.6 RLN70666.1 - 0.14 12.2 0.6 4.8 7.3 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L18A PF01775.17 RLN70667.1 - 4e-26 91.5 0.2 7.2e-26 90.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Got1 PF04178.12 RLN70668.1 - 8.7e-31 106.7 9.8 1.2e-30 106.2 9.8 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family PspB PF06667.12 RLN70668.1 - 2.3 8.3 6.4 0.18 11.9 1.4 1.8 2 0 0 2 2 2 0 Phage shock protein B Nup160 PF11715.8 RLN70669.1 - 3.4e-17 62.3 0.0 2.3e-16 59.6 0.0 2.0 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Pkr1 PF08636.10 RLN70670.1 - 1.3e-09 38.1 5.4 1.8e-09 37.6 5.4 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF4191 PF13829.6 RLN70670.1 - 0.11 11.8 0.8 0.14 11.5 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Ac76 PF05814.11 RLN70670.1 - 0.16 12.0 3.0 0.27 11.3 2.3 1.7 1 1 1 2 2 2 0 Orf76 (Ac76) Pox_A9 PF04835.12 RLN70670.1 - 0.17 12.0 0.3 0.17 12.0 0.3 2.0 2 0 0 2 2 2 0 A9 protein conserved region DUF2207 PF09972.9 RLN70670.1 - 0.23 10.2 1.1 0.34 9.6 1.1 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3852 PF12963.7 RLN70670.1 - 1.2 9.5 5.1 2 8.8 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3852) Exo_endo_phos PF03372.23 RLN70675.1 - 0.00051 19.6 0.0 0.0012 18.4 0.0 1.5 1 1 1 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Pkinase_Tyr PF07714.17 RLN70676.1 - 1.1e-48 165.7 0.0 1.4e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN70676.1 - 2e-47 161.8 0.0 2.5e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Insulin_TMD PF17870.1 RLN70676.1 - 0.044 13.8 0.1 0.085 12.9 0.1 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment TMEMspv1-c74-12 PF11044.8 RLN70676.1 - 0.21 11.6 0.3 0.43 10.6 0.3 1.5 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Pkinase_Tyr PF07714.17 RLN70677.1 - 1.8e-49 168.4 0.0 2.4e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN70677.1 - 1.3e-48 165.7 0.0 1.9e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 RLN70677.1 - 0.0038 16.2 0.0 0.021 13.8 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Orthoreo_P10 PF07204.11 RLN70677.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Pkinase_fungal PF17667.1 RLN70677.1 - 0.042 12.6 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 RLN70677.1 - 0.049 13.0 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sugar_tr PF00083.24 RLN70678.1 - 8e-84 282.1 26.0 9.6e-84 281.8 26.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN70678.1 - 1.4e-22 80.1 30.2 1.4e-22 80.1 30.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M24 PF00557.24 RLN70680.1 - 1.1e-38 133.1 0.2 1.8e-38 132.4 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 RLN70680.1 - 6.4e-27 93.7 0.2 2.4e-26 91.9 0.1 1.9 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain ParcG PF10274.9 RLN70681.1 - 1.5e-35 123.0 0.0 4.2e-35 121.5 0.0 1.8 2 1 0 2 2 2 1 Parkin co-regulated protein F-box-like PF12937.7 RLN70681.1 - 0.00077 19.3 0.8 0.0015 18.3 0.8 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RLN70681.1 - 0.027 14.4 1.1 0.053 13.4 1.1 1.5 1 0 0 1 1 1 0 F-box domain Colicin_V PF02674.16 RLN70682.1 - 0.0036 17.3 2.2 0.0036 17.3 2.2 3.6 3 1 1 4 4 4 2 Colicin V production protein cNMP_binding PF00027.29 RLN70683.1 - 1e-11 44.7 0.0 1.3e-08 34.7 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN70683.1 - 3.6e-06 26.4 11.2 1.1e-05 24.8 11.2 1.8 1 1 0 1 1 1 1 Ion transport protein Pex19 PF04614.12 RLN70683.1 - 3.9 7.2 7.0 1.8 8.3 0.3 2.9 3 0 0 3 3 3 0 Pex19 protein family DUF1639 PF07797.14 RLN70683.1 - 4.5 7.3 6.5 0.54 10.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1639) cNMP_binding PF00027.29 RLN70685.1 - 1.6e-13 50.6 1.0 5.1e-08 32.9 0.0 2.8 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain BEX PF04538.12 RLN70685.1 - 0.15 12.7 0.9 0.33 11.6 0.9 1.5 1 0 0 1 1 1 0 Brain expressed X-linked like family TMF_TATA_bd PF12325.8 RLN70685.1 - 0.22 11.8 0.5 0.43 10.8 0.1 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding GGACT PF06094.12 RLN70740.1 - 1.4e-20 74.1 0.3 2.8e-20 73.1 0.3 1.5 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 RLN70740.1 - 6.4e-07 29.7 0.0 1.2e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family Sdh5 PF03937.16 RLN70740.1 - 0.013 15.4 0.0 3.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Flavinator of succinate dehydrogenase Phage_integrase PF00589.22 RLN70741.1 - 3.8e-06 26.8 0.1 7.8e-06 25.8 0.0 1.5 2 0 0 2 2 2 1 Phage integrase family PP2C PF00481.21 RLN70745.1 - 1e-39 136.8 0.0 1.8e-39 135.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RLN70745.1 - 0.0022 17.6 1.6 0.0044 16.7 1.6 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C Myb_DNA-bind_4 PF13837.6 RLN70746.1 - 0.0026 18.1 0.0 0.0033 17.8 0.0 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF573 PF04504.14 RLN70746.1 - 0.032 14.9 0.0 0.041 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF573 Sirohm_synth_M PF14824.6 RLN70753.1 - 0.12 11.8 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central DnaJ PF00226.31 RLN70754.1 - 1.3e-15 57.2 0.0 2.4e-11 43.6 0.0 2.3 2 0 0 2 2 2 2 DnaJ domain SUIM_assoc PF16619.5 RLN70754.1 - 0.11 12.5 6.7 0.24 11.5 6.7 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 cNMP_binding PF00027.29 RLN70755.1 - 2.6e-09 37.0 0.0 5.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN70755.1 - 3.4e-06 26.5 1.0 0.00014 21.2 0.3 2.2 2 0 0 2 2 2 2 Ion transport protein DSL PF01414.19 RLN70755.1 - 0.00053 20.2 8.2 0.00053 20.2 8.2 3.5 2 1 1 3 3 3 2 Delta serrate ligand CENP-B_dimeris PF09026.10 RLN70755.1 - 7.5 7.0 12.4 18 5.8 12.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HA PF03457.14 RLN70756.1 - 1.1e-30 105.7 1.6 1.5e-06 28.5 0.1 6.4 6 0 0 6 6 6 5 Helicase associated domain SBF PF01758.16 RLN70756.1 - 3.3e-10 40.0 0.1 4.7e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 Sodium Bile acid symporter family PG_binding_2 PF08823.11 RLN70756.1 - 0.0029 17.9 0.8 7 7.0 0.0 3.9 5 0 0 5 5 5 2 Putative peptidoglycan binding domain Foie-gras_1 PF11817.8 RLN70757.1 - 6.6e-06 25.9 0.2 1.1e-05 25.1 0.2 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 CARD_2 PF16739.5 RLN70757.1 - 0.18 11.8 0.4 6.8 6.8 0.1 2.5 2 0 0 2 2 2 0 Caspase recruitment domain TPR_4 PF07721.14 RLN70757.1 - 0.24 12.1 2.3 3.9 8.4 0.1 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 RLN70761.1 - 1e-42 146.2 0.1 4.1e-22 78.7 0.0 2.4 1 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN70761.1 - 1.5e-35 122.8 0.0 3.8e-35 121.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 RLN70761.1 - 0.015 14.3 0.0 0.047 12.6 0.0 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Sugar_tr PF00083.24 RLN70762.1 - 2.5e-05 23.4 0.0 2.7e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter PSS PF03034.15 RLN70794.1 - 2.5e-91 306.2 13.4 3.8e-91 305.6 13.4 1.3 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF3382 PF11862.8 RLN70794.1 - 5.4 7.4 10.7 0.28 11.5 0.3 3.5 4 1 0 5 5 5 0 Domain of unknown function (DUF3382) SHMT PF00464.19 RLN70795.1 - 4.7e-173 575.4 0.0 5.8e-173 575.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 RLN70795.1 - 6.5e-05 22.3 0.0 0.00012 21.4 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase PALP PF00291.25 RLN70796.1 - 8.6e-45 153.4 0.1 3.1e-33 115.5 0.0 2.5 3 0 0 3 3 3 2 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 RLN70796.1 - 2.7e-16 59.7 0.1 1.2e-09 38.5 0.0 2.9 3 0 0 3 3 3 2 CBS domain DAGK_cat PF00781.24 RLN70796.1 - 0.083 12.5 0.1 0.86 9.2 0.0 2.5 3 0 0 3 3 3 0 Diacylglycerol kinase catalytic domain Sugar-bind PF04198.13 RLN70796.1 - 0.18 10.9 0.2 5.3 6.1 0.1 2.3 2 0 0 2 2 2 0 Putative sugar-binding domain FYVE PF01363.21 RLN70797.1 - 0.16 12.1 18.8 0.39 10.9 18.8 1.6 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN70797.1 - 0.87 9.8 15.4 2.2 8.5 15.4 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger FYVE_2 PF02318.16 RLN70798.1 - 0.00024 21.3 13.9 0.00085 19.5 13.9 1.9 1 1 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 RLN70798.1 - 0.00086 19.4 16.2 0.0017 18.4 15.8 1.8 2 0 0 2 2 2 1 FYVE zinc finger FYVE PF01363.21 RLN70799.1 - 3.7e-05 23.8 10.8 3.7e-05 23.8 10.8 1.8 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 RLN70799.1 - 0.0019 18.4 12.5 0.0046 17.2 6.2 2.4 1 1 1 2 2 2 2 FYVE-type zinc finger C1_2 PF03107.16 RLN70799.1 - 0.71 10.2 6.9 0.82 10.0 2.8 2.5 2 0 0 2 2 2 0 C1 domain IBR PF01485.21 RLN70799.1 - 2.8 8.2 17.2 5.8 7.2 7.6 4.0 2 2 0 2 2 2 0 IBR domain, a half RING-finger domain zf-B_box PF00643.24 RLN70799.1 - 4 7.7 10.1 0.21 11.8 2.4 2.7 3 0 0 3 3 3 0 B-box zinc finger Ribosomal_L7Ae PF01248.26 RLN70801.1 - 9.9e-08 31.6 0.0 1.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SWIRM-assoc_1 PF16495.5 RLN70801.1 - 0.28 11.2 2.5 0.75 9.8 0.8 2.2 2 0 0 2 2 2 0 SWIRM-associated region 1 ubiquitin PF00240.23 RLN70802.1 - 1.2e-18 66.6 0.0 2.8e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 RLN70802.1 - 0.0015 19.0 0.0 0.0039 17.6 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 RLN70802.1 - 0.0032 17.3 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 RLN70802.1 - 0.084 13.0 1.0 0.29 11.2 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DDHD PF02862.17 RLN70802.1 - 0.55 10.3 8.3 0.61 10.2 1.8 2.8 3 0 0 3 3 3 0 DDHD domain DUF2407 PF10302.9 RLN70802.1 - 1.8 9.2 0.0 1.8 9.2 0.0 2.9 3 0 0 3 3 3 0 DUF2407 ubiquitin-like domain Ank_2 PF12796.7 RLN70803.1 - 2.4e-14 53.6 0.0 1.7e-05 25.3 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN70803.1 - 3.2e-12 46.7 0.0 0.00012 22.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) SAM_1 PF00536.30 RLN70803.1 - 1.8e-11 44.3 0.0 4.1e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank PF00023.30 RLN70803.1 - 9.1e-11 41.7 0.1 1.3e-06 28.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RLN70803.1 - 1.2e-10 41.4 0.1 1.3e-05 25.4 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) SAM_2 PF07647.17 RLN70803.1 - 3.7e-10 39.8 0.0 6.9e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_3 PF13606.6 RLN70803.1 - 3.8e-10 39.1 0.0 5.6e-06 26.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Rhodanese PF00581.20 RLN70804.1 - 0.0094 16.5 0.0 0.25 11.9 0.0 2.6 1 1 0 1 1 1 1 Rhodanese-like domain UPF0444 PF15475.6 RLN70804.1 - 1.8 8.9 5.7 1.7 9.0 2.4 2.5 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 IPPT PF01715.17 RLN70805.1 - 1.1e-68 231.5 0.1 1.9e-68 230.7 0.0 1.4 2 0 0 2 2 2 1 IPP transferase DUF3449 PF11931.8 RLN70805.1 - 1.7e-07 31.2 0.4 4e-07 30.0 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) AAA_33 PF13671.6 RLN70805.1 - 4.9e-07 30.0 1.0 2.3e-06 27.8 0.2 2.5 2 1 0 2 2 2 1 AAA domain IPT PF01745.16 RLN70805.1 - 1.5e-05 24.5 0.1 3.4e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Isopentenyl transferase zf-met PF12874.7 RLN70805.1 - 2.1e-05 24.7 0.2 4.1e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RLN70805.1 - 3.9e-05 23.8 0.9 8.2e-05 22.8 0.9 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_18 PF13238.6 RLN70805.1 - 0.0015 19.0 0.6 0.25 11.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain zf-C2H2_2 PF12756.7 RLN70805.1 - 0.0036 17.6 0.7 0.019 15.3 0.3 2.1 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) NACHT PF05729.12 RLN70805.1 - 0.051 13.5 0.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 RLN70805.1 - 0.066 13.2 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE zf-C2H2_4 PF13894.6 RLN70805.1 - 0.072 14.0 0.2 1.1 10.3 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger AAA_28 PF13521.6 RLN70805.1 - 0.1 12.8 0.9 0.42 10.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain RIBIOP_C PF04950.12 RLN70806.1 - 3.7e-98 328.6 0.9 1.4e-97 326.6 0.0 2.2 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 RLN70806.1 - 7.4e-21 74.0 0.0 2.1e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Nop14 PF04147.12 RLN70806.1 - 6 4.9 21.3 9.8 4.2 21.3 1.2 1 0 0 1 1 1 0 Nop14-like family ubiquitin PF00240.23 RLN70807.1 - 5.5e-19 67.7 0.0 9.1e-19 67.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RLN70807.1 - 4.4e-06 26.4 0.0 6.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 RLN70807.1 - 0.0094 16.0 0.0 0.025 14.7 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 RLN70807.1 - 0.088 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DEAD PF00270.29 RLN70808.1 - 1.6e-37 129.0 0.0 3.8e-37 127.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN70808.1 - 1.6e-19 70.3 0.0 3.5e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN70808.1 - 3.2e-09 37.0 0.0 6.5e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RLN70808.1 - 0.06 13.6 0.3 15 5.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain Methyltransf_28 PF02636.17 RLN70809.1 - 0.14 11.8 0.3 1.4 8.5 0.2 2.0 1 1 1 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase FAM183 PF14886.6 RLN70810.1 - 5.4e-08 33.5 4.9 1.6e-05 25.6 4.9 3.1 1 1 0 1 1 1 1 FAM183A and FAM183B related SpoU_methylase PF00588.19 RLN70824.1 - 1.8e-22 80.0 0.1 2.2e-22 79.8 0.1 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family NAD_binding_11 PF14833.6 RLN70824.1 - 0.029 14.6 0.1 0.059 13.6 0.1 1.5 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase TSP_1 PF00090.19 RLN70830.1 - 7.1e-66 218.2 431.6 6.2e-05 23.1 2.6 45.1 45 0 0 45 45 45 37 Thrombospondin type 1 domain PTN_MK_C PF01091.18 RLN70830.1 - 4.8e-11 42.9 259.5 0.078 13.4 0.2 39.0 37 4 4 41 41 41 22 PTN/MK heparin-binding protein family, C-terminal domain LEA_6 PF10714.9 RLN70830.1 - 0.57 10.3 3.7 1.9 8.6 0.5 3.7 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 DUF2568 PF10823.8 RLN70830.1 - 9.6 6.6 17.4 15 6.0 0.0 8.6 9 1 1 10 10 10 0 Protein of unknown function (DUF2568) Dynein_light PF01221.18 RLN70832.1 - 4.2e-24 84.7 0.4 4.8e-24 84.5 0.4 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 CxC6 PF18721.1 RLN70833.1 - 0.0012 19.0 1.4 0.0012 19.0 1.4 4.2 1 1 1 3 3 3 1 CxC6 like cysteine cluster associated with KDZ transposases DUF3586 PF12131.8 RLN70833.1 - 0.0068 16.6 4.9 0.0068 16.6 4.9 3.7 1 1 2 4 4 4 1 Protein of unknown function (DUF3586) DDE_1 PF03184.19 RLN70846.1 - 3.6e-17 62.6 0.0 8.3e-17 61.4 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 RLN70846.1 - 1.8e-05 24.5 0.0 0.065 13.0 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease Plasmo_rep PF12135.8 RLN70846.1 - 0.085 12.4 0.3 0.15 11.6 0.3 1.3 1 0 0 1 1 1 0 Plasmodium repeat family EF-hand_1 PF00036.32 RLN70847.1 - 6.7e-05 22.2 0.7 0.00082 18.8 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 RLN70847.1 - 0.0008 19.8 0.1 0.0017 18.7 0.1 1.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN70847.1 - 0.0013 18.1 0.2 0.0031 17.0 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 RLN70847.1 - 0.0058 16.5 0.1 0.02 14.8 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 RLN70847.1 - 0.058 13.2 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair PH PF00169.29 RLN70858.1 - 0.00057 20.4 0.1 0.0012 19.3 0.1 1.7 1 1 0 1 1 1 1 PH domain AAA_26 PF13500.6 RLN70859.1 - 7e-46 156.6 0.0 2.6e-45 154.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain HAD_2 PF13419.6 RLN70859.1 - 1.2e-08 35.2 0.1 7.2e-08 32.7 0.1 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DRTGG PF07085.12 RLN70859.1 - 2e-08 34.0 0.0 4.4e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 DRTGG domain Hydrolase_like PF13242.6 RLN70859.1 - 8.4e-08 32.2 0.9 2e-07 31.0 0.1 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 RLN70859.1 - 4.9e-06 27.0 0.0 1.3e-05 25.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CbiA PF01656.23 RLN70859.1 - 0.068 13.2 0.0 0.52 10.4 0.0 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Nrap_D3 PF17404.2 RLN70869.1 - 2e-42 145.0 0.4 3.4e-42 144.2 0.4 1.4 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D4 PF17405.2 RLN70869.1 - 1.3e-41 142.4 0.0 2.2e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 RLN70869.1 - 8.1e-40 136.2 1.8 1.9e-38 131.8 0.3 2.5 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap PF03813.14 RLN70869.1 - 6.1e-37 127.0 0.0 1.4e-36 125.9 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 RLN70869.1 - 7.5e-35 119.9 1.1 1.9e-34 118.6 0.6 2.0 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D6 PF17407.2 RLN70869.1 - 3.9e-10 40.1 0.0 7.8e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 6 ADH_N PF08240.12 RLN70870.1 - 1.7e-25 89.0 0.9 3.2e-25 88.1 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN70870.1 - 2.7e-23 82.4 0.1 4.8e-23 81.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 RLN70870.1 - 0.00026 20.4 0.3 0.00044 19.6 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 RLN70870.1 - 0.0054 16.1 0.1 0.0087 15.4 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 RLN70870.1 - 0.037 15.1 0.0 0.08 14.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 RLN70870.1 - 0.039 13.5 0.1 0.064 12.8 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ubiquitin PF00240.23 RLN70870.1 - 0.054 13.3 0.1 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin family Hist_deacetyl PF00850.19 RLN70871.1 - 7e-78 262.2 0.1 9.3e-78 261.8 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain F-box-like PF12937.7 RLN70871.1 - 0.0019 18.1 0.7 0.0048 16.8 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 RLN70871.1 - 0.17 11.5 1.2 0.36 10.4 1.2 1.5 1 0 0 1 1 1 0 F-box Ax_dynein_light PF10211.9 RLN70872.1 - 8e-85 283.5 14.0 9.3e-85 283.3 14.0 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain APG6_N PF17675.1 RLN70872.1 - 0.0017 18.9 10.7 0.0017 18.9 10.7 1.5 2 0 0 2 2 2 1 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 RLN70872.1 - 0.0087 16.3 16.2 0.026 14.8 12.5 2.1 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 RLN70872.1 - 0.3 11.2 7.9 0.59 10.2 7.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 RLN70872.1 - 0.54 10.7 3.7 8.2 6.9 0.4 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) PRKG1_interact PF15898.5 RLN70872.1 - 1.7 9.6 14.2 0.71 10.8 11.8 1.6 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DivIC PF04977.15 RLN70872.1 - 2.8 7.8 14.1 0.93 9.3 3.9 2.5 1 1 1 2 2 2 0 Septum formation initiator Myc-LZ PF02344.15 RLN70872.1 - 3.3 7.9 11.1 1 9.5 0.3 3.4 3 0 0 3 3 3 0 Myc leucine zipper domain Spc24 PF08286.11 RLN70872.1 - 4.2 7.7 10.0 12 6.1 9.7 1.9 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Glyco_hydro_3_C PF01915.22 RLN70873.1 - 1.2e-51 175.6 0.0 1.7e-51 175.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 RLN70873.1 - 2.1e-36 125.9 0.0 8.8e-36 123.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 RLN70873.1 - 9.9e-05 22.4 0.0 0.00021 21.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain SBP_bac_11 PF13531.6 RLN70887.1 - 4.1e-14 52.9 0.2 5.6e-14 52.4 0.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Telomere_reg-2 PF10193.9 RLN70901.1 - 5.1e-24 84.8 1.1 1.1e-23 83.7 1.1 1.6 1 0 0 1 1 1 1 Telomere length regulation protein Myb_DNA-binding PF00249.31 RLN70901.1 - 6.8e-15 55.0 3.3 1.9e-05 24.8 0.2 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN70901.1 - 2.4e-08 34.1 5.0 0.012 15.8 0.0 3.8 3 0 0 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 RLN70901.1 - 0.00021 21.3 0.0 0.082 12.9 0.0 2.7 2 0 0 2 2 2 2 SLIDE DUF4611 PF15387.6 RLN70901.1 - 0.42 10.9 5.7 2.4 8.4 4.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PGA2 PF07543.12 RLN70901.1 - 0.58 10.1 2.7 7.1 6.6 0.8 2.8 2 0 0 2 2 2 0 Protein trafficking PGA2 Ank_4 PF13637.6 RLN70902.1 - 1.1e-34 118.3 14.9 1.9e-06 28.3 0.2 8.2 4 2 5 9 9 9 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN70902.1 - 8.8e-33 112.7 19.1 5.2e-09 36.6 0.1 6.5 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN70902.1 - 3.8e-29 100.4 22.0 0.0036 17.6 0.1 13.1 3 3 10 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN70902.1 - 5.8e-22 75.4 0.9 0.77 10.5 0.0 13.0 12 1 1 13 13 13 4 Ankyrin repeat DUF5049 PF16468.5 RLN70902.1 - 5.6e-10 39.0 1.2 6 6.8 0.0 8.1 3 2 6 9 9 9 3 Domain of unknown function (DUF5049) Ank PF00023.30 RLN70902.1 - 0.012 16.0 1.1 91 3.8 0.0 6.4 5 2 1 6 6 6 0 Ankyrin repeat Acyl-CoA_dh_1 PF00441.24 RLN70902.1 - 0.013 15.7 1.0 0.057 13.6 1.0 2.1 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain HOIP-UBA PF16678.5 RLN70902.1 - 0.025 14.6 3.0 5.1 7.1 0.1 3.5 2 1 1 3 3 3 0 HOIP UBA domain pair Myb_DNA-binding PF00249.31 RLN70908.1 - 2.5e-29 101.2 6.8 3.3e-14 52.8 1.7 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN70908.1 - 1.6e-21 76.3 3.4 5e-17 61.9 0.4 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 RLN70908.1 - 0.0014 18.8 0.8 0.0069 16.6 0.1 2.2 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 RLN70908.1 - 0.002 18.4 0.3 0.002 18.4 0.3 2.6 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN70908.1 - 0.0036 17.2 0.6 0.027 14.4 0.2 2.3 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 RLN70908.1 - 0.029 14.4 0.0 0.096 12.7 0.0 1.9 2 0 0 2 2 2 0 SLIDE IRF PF00605.17 RLN70908.1 - 0.2 12.0 0.9 0.49 10.7 0.9 1.6 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor Myb_DNA-bind_2 PF08914.11 RLN70908.1 - 2 8.7 6.3 0.24 11.6 0.5 2.5 1 1 1 2 2 2 0 Rap1 Myb domain AA_permease_2 PF13520.6 RLN70909.1 - 3e-30 105.4 19.5 3.3e-30 105.3 19.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN70909.1 - 2.6e-22 79.1 19.0 2.9e-22 78.9 19.0 1.0 1 0 0 1 1 1 1 Amino acid permease WD40 PF00400.32 RLN70928.1 - 4.5e-19 68.4 6.4 2.5e-06 28.1 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Lgl_C PF08596.10 RLN70928.1 - 0.13 10.9 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal Vps54 PF07928.12 RLN70929.1 - 4.5e-24 85.4 9.4 1.2e-13 51.7 0.3 3.6 4 0 0 4 4 4 2 Vps54-like protein Vps54_N PF10475.9 RLN70929.1 - 9.7e-08 31.6 1.6 9.7e-08 31.6 1.6 2.7 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex MBD PF01429.19 RLN70929.1 - 0.057 13.1 0.1 0.18 11.5 0.1 1.9 1 0 0 1 1 1 0 Methyl-CpG binding domain Sec8_exocyst PF04048.14 RLN70929.1 - 1.2 9.0 5.5 0.25 11.3 0.8 2.4 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain G-alpha PF00503.20 RLN70929.1 - 1.4 8.0 6.7 18 4.3 0.0 3.6 3 1 0 3 3 3 0 G-protein alpha subunit Lipase_3 PF01764.25 RLN70930.1 - 1.2e-11 44.6 0.0 2.9e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DFP PF04127.15 RLN70930.1 - 6.8e-06 26.0 0.5 0.0006 19.7 0.1 3.2 2 1 1 3 3 3 1 DNA / pantothenate metabolism flavoprotein PE-PPE PF08237.11 RLN70930.1 - 0.0029 17.2 0.0 0.006 16.2 0.0 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.7 RLN70930.1 - 0.0075 16.9 0.1 0.0075 16.9 0.1 2.8 3 1 0 3 3 3 1 Alpha/beta hydrolase family Thioesterase PF00975.20 RLN70930.1 - 0.0077 16.4 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Thr_dehydrat_C PF00585.18 RLN70930.1 - 0.13 12.1 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase Carn_acyltransf PF00755.20 RLN70931.1 - 1e-164 549.4 0.0 1.2e-164 549.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Fez1 PF06818.15 RLN70932.1 - 0.028 14.9 13.8 0.042 14.3 13.8 1.2 1 0 0 1 1 1 0 Fez1 FlaF PF07309.11 RLN70932.1 - 0.11 12.5 3.5 0.16 12.0 3.0 1.5 1 1 0 1 1 1 0 Flagellar protein FlaF Exonuc_VII_L PF02601.15 RLN70932.1 - 4.5 6.7 10.4 5.8 6.4 10.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit LSM PF01423.22 RLN70933.1 - 6.3e-16 57.8 0.2 9.5e-16 57.3 0.2 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 RLN70933.1 - 0.0047 16.6 0.0 0.0085 15.7 0.0 1.3 1 0 0 1 1 1 1 Hfq protein EGF_2 PF07974.13 RLN70934.1 - 0.0076 16.6 7.1 0.0076 16.6 7.1 5.7 4 1 0 4 4 4 3 EGF-like domain Apt1 PF10351.9 RLN70934.1 - 2.9 6.7 11.1 3.8 6.3 11.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SET PF00856.28 RLN70935.1 - 1.1e-15 58.5 0.1 6.6e-15 55.9 0.1 1.9 1 1 0 1 1 1 1 SET domain EF-hand_1 PF00036.32 RLN70937.1 - 2e-11 42.6 0.7 6.1e-05 22.3 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN70937.1 - 3.2e-10 39.1 0.6 9.5e-05 22.0 0.3 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RLN70937.1 - 2.1e-09 37.7 0.0 5e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RLN70937.1 - 1.2e-05 25.0 0.2 0.041 13.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN70937.1 - 0.00016 21.0 2.7 0.043 13.3 0.2 2.5 2 0 0 2 2 2 2 EF hand zf-C4 PF00105.18 RLN70937.1 - 0.015 15.8 1.0 0.032 14.7 0.3 1.9 2 0 0 2 2 2 0 Zinc finger, C4 type (two domains) zf-TRAF PF02176.18 RLN70937.1 - 0.065 13.9 0.1 0.14 12.9 0.1 1.5 1 0 0 1 1 1 0 TRAF-type zinc finger Zn-ribbon_8 PF09723.10 RLN70937.1 - 0.22 11.7 0.8 0.4 10.8 0.1 1.8 2 0 0 2 2 2 0 Zinc ribbon domain Ferric_reduct PF01794.19 RLN70938.1 - 9.9e-19 67.7 11.5 9.9e-19 67.7 11.5 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 RLN70938.1 - 1.6e-12 47.4 0.0 6.2e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 RLN70938.1 - 1.2e-06 28.8 0.0 7.5e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 RLN70938.1 - 0.0088 16.4 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain SrfB PF07520.11 RLN70939.1 - 0.0022 16.0 0.0 0.003 15.5 0.0 1.1 1 0 0 1 1 1 1 Virulence factor SrfB 7tm_7 PF08395.12 RLN70940.1 - 0.0091 15.2 0.5 0.011 15.0 0.5 1.0 1 0 0 1 1 1 1 7tm Chemosensory receptor 7TMR-DISM_7TM PF07695.11 RLN70940.1 - 0.011 15.6 1.2 0.014 15.3 1.2 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling Claudin_3 PF06653.11 RLN70940.1 - 0.013 15.4 0.7 0.018 15.0 0.7 1.1 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Cytochrome-c551 PF10643.9 RLN70940.1 - 0.041 13.4 0.5 0.061 12.9 0.5 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 DUF3810 PF12725.7 RLN70940.1 - 0.053 12.9 0.1 0.061 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) FMN_red PF03358.15 RLN70947.1 - 1.2e-10 41.3 0.0 1.6e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 RLN70947.1 - 0.0085 15.8 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold Aminotran_5 PF00266.19 RLN70948.1 - 1.3e-36 126.4 0.0 1.6e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_5 PF00266.19 RLN70950.1 - 2.5e-43 148.5 0.0 3.8e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V ATP_bind_3 PF01171.20 RLN70950.1 - 2e-15 57.0 0.0 4.4e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 PP-loop family Aminotran_1_2 PF00155.21 RLN70950.1 - 0.093 11.9 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class I and II Cellulase PF00150.18 RLN70951.1 - 2.2e-07 30.6 0.0 3.1e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Aminotran_5 PF00266.19 RLN70952.1 - 1.4e-38 132.8 0.0 1.7e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_5 PF00266.19 RLN70953.1 - 8e-39 133.6 0.0 1.2e-38 133.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V 2-Hacid_dh_C PF02826.19 RLN70957.1 - 8.5e-56 188.1 0.0 1.1e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 RLN70957.1 - 9.3e-29 99.8 0.0 1.3e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 RLN70957.1 - 0.042 14.4 0.0 0.11 13.1 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF4440 PF14534.6 RLN70957.1 - 0.11 12.9 0.0 0.56 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) Dioxygenase_C PF00775.21 RLN70958.1 - 3.4e-09 36.4 0.1 6.4e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase TRAF_BIRC3_bd PF16673.5 RLN70958.1 - 0.11 12.2 0.6 0.28 11.0 0.6 1.6 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain DUF1467 PF07330.12 RLN70959.1 - 0.093 12.7 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) TRAM_LAG1_CLN8 PF03798.16 RLN70961.1 - 4.9e-06 26.4 0.5 4.9e-06 26.4 0.5 1.6 2 0 0 2 2 2 1 TLC domain TRAM_LAG1_CLN8 PF03798.16 RLN70962.1 - 4.5e-25 88.5 16.5 5.6e-25 88.2 16.5 1.0 1 0 0 1 1 1 1 TLC domain Aminotran_4 PF01063.19 RLN70963.1 - 3.9e-20 72.7 0.0 2.6e-19 70.0 0.0 1.9 1 1 0 1 1 1 1 Amino-transferase class IV Ntox30 PF15532.6 RLN70963.1 - 0.052 13.9 0.0 7.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial toxin 30 SecE PF00584.20 RLN70964.1 - 5.6e-15 55.0 0.0 6.5e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex TPR_2 PF07719.17 RLN70965.1 - 0.023 14.8 4.8 25 5.3 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1289 PF06945.13 RLN70965.1 - 0.17 11.8 1.5 1.4 8.8 1.5 2.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) Ank_2 PF12796.7 RLN70966.1 - 2.5e-26 92.1 0.0 1.7e-08 34.9 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN70966.1 - 5.4e-25 87.4 5.3 7.6e-12 45.5 0.0 4.4 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN70966.1 - 4.3e-24 83.8 0.1 1.9e-05 24.9 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 RLN70966.1 - 7e-21 74.0 2.9 4.7e-07 29.9 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN70966.1 - 9.1e-20 68.7 0.2 0.0021 18.4 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat SDA1 PF05285.12 RLN70966.1 - 0.0014 18.2 7.8 0.0014 18.2 7.8 2.1 2 0 0 2 2 2 1 SDA1 DUF4366 PF14283.6 RLN70966.1 - 0.0065 16.5 0.4 0.0065 16.5 0.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) BSP_II PF05432.11 RLN70966.1 - 0.16 11.7 17.2 0.31 10.7 17.2 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CPSF100_C PF13299.6 RLN70966.1 - 0.46 10.7 7.2 0.3 11.3 2.6 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal TRAP_alpha PF03896.16 RLN70966.1 - 1.1 8.5 9.4 1.9 7.7 9.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF913 PF06025.12 RLN70966.1 - 1.4 7.8 3.3 2.5 7.0 3.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) COPI_C PF06957.11 RLN70966.1 - 7.9 5.1 9.3 14 4.3 9.3 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus FAM176 PF14851.6 RLN70966.1 - 9.9 5.8 11.8 30 4.3 11.8 1.8 1 0 0 1 1 1 0 FAM176 family RNA_pol_Rpb1_2 PF00623.20 RLN70967.1 - 3.1e-76 255.2 0.4 8.1e-76 253.9 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 RLN70967.1 - 3.9e-58 197.2 0.0 7.9e-58 196.2 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 RLN70967.1 - 5.9e-47 159.5 0.1 2e-46 157.8 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 RLN70967.1 - 2.8e-34 117.3 0.0 5.2e-34 116.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 PF04998.17 RLN70967.1 - 4.4e-32 111.6 0.2 9.7e-32 110.4 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_6 PF04992.14 RLN70967.1 - 7.9e-05 22.6 0.1 0.00015 21.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 PP2C PF00481.21 RLN70974.1 - 4.1e-61 206.9 0.0 4.7e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RLN70974.1 - 2.3e-06 27.4 0.1 8.8e-06 25.5 0.1 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 RLN70974.1 - 0.17 11.8 0.0 2.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Pyr_redox_2 PF07992.14 RLN70976.1 - 8.9e-20 71.1 0.0 1.4e-19 70.4 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RLN70976.1 - 3.6e-09 36.5 0.0 4.2e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RLN70976.1 - 1.6e-08 34.6 0.8 7.9e-06 26.0 0.1 2.4 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 RLN70976.1 - 9.1e-08 32.6 4.7 0.0021 18.6 0.3 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RLN70976.1 - 4.7e-07 28.9 3.4 3.8e-06 25.9 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 RLN70976.1 - 1e-06 28.1 0.5 1e-06 28.1 0.5 2.2 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 RLN70976.1 - 2.6e-06 26.9 1.6 0.0017 17.7 0.2 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 RLN70976.1 - 7.9e-05 22.0 1.0 0.013 14.7 0.0 2.5 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.22 RLN70976.1 - 0.00054 19.2 1.5 0.0012 18.0 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 RLN70976.1 - 0.00071 19.3 4.9 0.0023 17.6 0.2 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 RLN70976.1 - 0.0018 17.6 5.3 0.0094 15.2 0.5 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 RLN70976.1 - 0.0031 17.1 3.9 4.3 6.9 0.6 3.4 4 0 0 4 4 4 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 RLN70976.1 - 0.0084 15.4 2.3 0.094 11.9 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain XdhC_C PF13478.6 RLN70976.1 - 0.016 15.7 0.2 6.3 7.3 0.1 2.4 2 1 0 2 2 2 0 XdhC Rossmann domain TrkA_N PF02254.18 RLN70976.1 - 0.026 14.8 2.2 6.5 7.0 0.3 2.9 3 0 0 3 3 3 0 TrkA-N domain Lycopene_cycl PF05834.12 RLN70976.1 - 0.057 12.5 2.9 0.14 11.2 0.3 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.18 RLN70976.1 - 0.1 12.4 4.2 2.9 7.7 0.2 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thiolase_N PF00108.23 RLN70977.1 - 2.7e-87 292.4 0.1 4e-87 291.9 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RLN70977.1 - 1.6e-45 153.8 1.8 2.9e-45 152.9 0.7 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 RLN70977.1 - 3e-05 23.7 1.3 3e-05 23.7 1.3 3.2 3 1 1 4 4 4 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 RLN70977.1 - 0.15 11.9 4.9 16 5.5 0.1 3.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Pex2_Pex12 PF04757.14 RLN70978.1 - 1e-37 129.9 4.1 1.2e-37 129.7 4.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 RLN70978.1 - 1.1e-05 25.2 4.1 1.9e-05 24.4 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN70978.1 - 1.3e-05 24.9 2.1 2.3e-05 24.1 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN70978.1 - 0.0037 17.1 1.6 0.0076 16.1 1.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN70978.1 - 0.0044 17.3 2.2 0.012 16.0 2.2 1.7 1 1 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 RLN70978.1 - 0.025 14.4 3.3 0.044 13.6 3.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 RLN70978.1 - 0.043 13.8 5.9 0.084 12.9 5.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 RLN70978.1 - 0.65 10.2 7.1 1.2 9.4 7.1 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RRM_1 PF00076.22 RLN70979.1 - 3.3e-15 55.6 0.4 5.5e-15 54.9 0.4 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN70979.1 - 5.4e-06 26.4 0.3 1e-05 25.6 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif LXG PF04740.12 RLN70980.1 - 0.011 15.5 5.4 0.16 11.7 5.4 2.3 1 1 0 1 1 1 0 LXG domain of WXG superfamily ING PF12998.7 RLN70980.1 - 0.023 15.3 2.0 0.023 15.3 2.0 1.9 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding AAA_35 PF14516.6 RLN70980.1 - 0.037 12.9 0.2 0.071 11.9 0.2 1.4 1 0 0 1 1 1 0 AAA-like domain KELK PF15796.5 RLN70980.1 - 0.056 13.9 0.6 0.056 13.9 0.6 2.3 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FCH PF00611.23 RLN70980.1 - 0.12 12.6 0.1 0.12 12.6 0.1 3.0 4 0 0 4 4 4 0 Fes/CIP4, and EFC/F-BAR homology domain Fez1 PF06818.15 RLN70980.1 - 2.5 8.5 10.6 2.7 8.4 8.5 2.0 1 1 1 2 2 2 0 Fez1 Lipase_3 PF01764.25 RLN70990.1 - 3.3e-16 59.4 0.0 5.9e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 RLN70990.1 - 0.066 13.8 0.1 0.14 12.7 0.1 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family CENP-B_dimeris PF09026.10 RLN70990.1 - 0.08 13.3 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM199X PF15814.5 RLN70990.1 - 0.13 11.3 5.0 0.21 10.6 5.0 1.3 1 0 0 1 1 1 0 Protein family FAM199X Myotub-related PF06602.14 RLN70991.1 - 3.7e-116 387.9 0.0 4.9e-116 387.5 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 RLN70991.1 - 0.00076 19.1 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RLN70991.1 - 0.001 19.1 0.1 0.002 18.2 0.1 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 RLN70991.1 - 0.024 14.5 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain zf-RanBP PF00641.18 RLN70991.1 - 0.038 13.3 2.3 0.093 12.1 2.3 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others 3-PAP PF12578.8 RLN70991.1 - 0.097 12.4 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Myotubularin-associated protein Prok-RING_2 PF14445.6 RLN70991.1 - 0.13 12.4 0.7 0.31 11.3 0.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 CAP PF00188.26 RLN70992.1 - 2.2e-18 67.3 1.5 2.2e-18 67.3 1.5 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family HhH-GPD PF00730.25 RLN70993.1 - 3.3e-10 40.4 0.0 5.7e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein OGG_N PF07934.12 RLN70993.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain FPN1 PF06963.12 RLN70994.1 - 1.7e-86 290.5 13.7 1.9e-86 290.4 13.7 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) MFS_1 PF07690.16 RLN70994.1 - 0.0006 18.8 9.8 0.0006 18.8 9.8 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily Pectate_lyase PF03211.13 RLN70995.1 - 1.8e-72 243.2 7.1 2.2e-72 242.9 7.1 1.1 1 0 0 1 1 1 1 Pectate lyase Pectate_lyase PF03211.13 RLN70996.1 - 1.2e-73 247.0 6.7 1.5e-73 246.7 6.7 1.0 1 0 0 1 1 1 1 Pectate lyase Bacteriocin_II PF01721.18 RLN70996.1 - 0.79 9.9 6.2 0.13 12.4 1.6 2.1 2 0 0 2 2 2 0 Class II bacteriocin Pectate_lyase PF03211.13 RLN70997.1 - 3.3e-17 62.7 0.1 3.7e-17 62.5 0.1 1.1 1 0 0 1 1 1 1 Pectate lyase Porin_4 PF13609.6 RLN70997.1 - 0.0028 17.5 0.0 0.0032 17.3 0.0 1.0 1 0 0 1 1 1 1 Gram-negative porin Trypan_PARP PF05887.11 RLN71000.1 - 0.6 10.1 15.6 3.1 7.8 15.6 2.0 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Phage_holin_5_2 PF16079.5 RLN71000.1 - 3.8 7.9 8.6 6.6 7.2 8.6 1.3 1 0 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V Neisseria_TspB PF05616.13 RLN71000.1 - 8.7 4.7 11.5 10 4.5 11.5 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein adh_short PF00106.25 RLN71001.1 - 1.9e-32 112.4 0.9 1.4e-27 96.5 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN71001.1 - 2.9e-19 69.6 0.4 6.3e-19 68.5 0.1 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN71001.1 - 8.1e-10 38.9 0.1 1.4e-09 38.1 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN71001.1 - 6.6e-06 25.7 0.1 9.2e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 RLN71001.1 - 0.0014 18.0 0.2 0.0028 17.0 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HA PF03457.14 RLN71002.1 - 6.2e-32 109.7 0.4 2.1e-06 27.9 0.1 6.4 6 0 0 6 6 6 6 Helicase associated domain PG_binding_2 PF08823.11 RLN71002.1 - 0.0013 19.0 0.6 5.8 7.3 0.0 4.0 5 0 0 5 5 5 2 Putative peptidoglycan binding domain MITF_TFEB_C_3_N PF15951.5 RLN71002.1 - 0.031 14.9 1.0 0.059 14.0 1.0 1.4 1 0 0 1 1 1 0 MITF/TFEB/TFEC/TFE3 N-terminus Foie-gras_1 PF11817.8 RLN71003.1 - 3.4e-06 26.9 0.1 6.5e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 DnaJ PF00226.31 RLN71004.1 - 4.8e-13 49.0 0.0 9e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain PD-C2-AF1 PF09310.10 RLN71004.1 - 0.017 14.6 0.2 0.023 14.1 0.2 1.1 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 DUF3446 PF11928.8 RLN71004.1 - 0.018 15.3 0.3 0.036 14.4 0.3 1.5 1 0 0 1 1 1 0 Early growth response N-terminal domain Ion_trans PF00520.31 RLN71005.1 - 1.6e-22 80.0 6.4 2.4e-22 79.4 6.4 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RLN71005.1 - 3.5e-14 52.5 4.2 8.8e-14 51.2 4.2 1.8 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 RLN71005.1 - 7.6e-09 35.5 0.0 1.8e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CENP-B_dimeris PF09026.10 RLN71005.1 - 0.06 13.7 9.1 0.15 12.4 9.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PP2C PF00481.21 RLN71007.1 - 1.8e-44 152.3 0.1 6.7e-44 150.4 0.1 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RLN71007.1 - 4.3e-06 26.5 0.0 6.4e-06 26.0 0.0 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C TFIIS_C PF01096.18 RLN71008.1 - 1.9e-17 62.8 1.6 4.6e-17 61.6 1.6 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) PA PF02225.22 RLN71008.1 - 4e-10 39.6 0.0 7.6e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 PA domain Zn_Tnp_IS1595 PF12760.7 RLN71008.1 - 0.033 14.2 0.8 0.076 13.0 0.8 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 RLN71008.1 - 0.048 13.8 6.6 0.82 9.8 1.0 3.2 3 0 0 3 3 3 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.17 RLN71008.1 - 0.11 12.4 2.6 0.094 12.6 1.0 1.7 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Baculo_LEF5_C PF11792.8 RLN71008.1 - 0.14 11.8 0.8 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain zf-TFIIB PF13453.6 RLN71008.1 - 0.23 10.8 1.0 0.48 9.8 1.0 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger RNA_POL_M_15KD PF02150.16 RLN71008.1 - 0.28 11.1 3.9 1.5 8.7 3.9 2.0 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit zinc_ribbon_4 PF13717.6 RLN71008.1 - 0.85 9.6 3.6 4.4 7.3 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf_UBZ PF18439.1 RLN71008.1 - 1.9 8.1 3.7 6 6.5 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-ribbon_3 PF13248.6 RLN71008.1 - 2.4 7.7 4.8 8.5 5.9 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf_C2H2_10 PF18414.1 RLN71008.1 - 4.4 6.9 4.7 0.82 9.3 0.1 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger HECT PF00632.25 RLN71009.1 - 3.9e-79 266.3 0.0 4.5e-79 266.1 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF3523 PF12037.8 RLN71009.1 - 0.23 10.8 0.0 0.33 10.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) GMP_PDE_delta PF05351.11 RLN71012.1 - 3.7e-60 202.5 0.1 4.9e-60 202.2 0.1 1.1 1 0 0 1 1 1 1 GMP-PDE, delta subunit SLBP_RNA_bind PF15247.6 RLN71013.1 - 1.4e-22 79.6 3.7 7.9e-22 77.2 3.7 2.1 1 1 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain EFG_IV PF03764.18 RLN71014.1 - 1.3e-36 125.1 0.2 2.7e-36 124.0 0.2 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 RLN71014.1 - 1.9e-34 117.6 0.1 4.6e-34 116.3 0.0 1.7 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 RLN71014.1 - 2.4e-25 88.4 0.0 9.7e-25 86.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 RLN71014.1 - 2.6e-11 43.7 0.4 1.1e-10 41.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 RLN71014.1 - 3.5e-07 30.1 0.1 7.1e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Mito_carr PF00153.27 RLN71015.1 - 1e-50 169.6 9.1 6e-21 74.2 0.0 3.5 4 0 0 4 4 4 3 Mitochondrial carrier protein DUF5321 PF17254.2 RLN71016.1 - 3.7 7.0 7.7 7.4 6.0 7.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5321) Arm PF00514.23 RLN71017.1 - 6.1e-19 67.4 3.1 5.5e-06 26.2 0.1 3.4 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat Ank_2 PF12796.7 RLN71017.1 - 4.6e-09 36.8 0.3 2.1e-08 34.6 0.0 2.2 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN71017.1 - 2.1e-08 34.2 0.1 2e-07 31.1 0.2 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN71017.1 - 4.3e-08 33.5 0.0 1.4e-07 31.9 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN71017.1 - 1.2e-06 28.4 0.0 0.003 17.9 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat HEAT_2 PF13646.6 RLN71017.1 - 6e-05 23.4 2.7 0.0005 20.4 0.9 2.5 1 1 1 2 2 2 2 HEAT repeats Ank PF00023.30 RLN71017.1 - 6.2e-05 23.3 0.1 0.17 12.4 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Arm_2 PF04826.13 RLN71017.1 - 0.0035 16.8 0.9 0.0072 15.8 0.9 1.4 1 1 0 1 1 1 1 Armadillo-like HEAT_EZ PF13513.6 RLN71017.1 - 0.049 14.2 3.5 1.2 9.8 0.1 3.2 2 1 1 3 3 3 0 HEAT-like repeat HEAT PF02985.22 RLN71017.1 - 5.2 7.6 4.9 5.8 7.5 0.1 3.2 4 0 0 4 4 4 0 HEAT repeat Ank_2 PF12796.7 RLN71018.1 - 1.5e-22 80.0 0.1 3.9e-09 37.0 0.1 4.5 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN71018.1 - 2e-20 72.9 11.1 0.00013 22.4 0.7 7.9 4 3 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN71018.1 - 5.6e-15 55.2 11.1 0.012 15.9 0.0 8.2 3 2 5 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN71018.1 - 6.6e-13 47.6 1.4 1 10.1 0.1 8.5 7 2 2 9 9 9 3 Ankyrin repeat Ank PF00023.30 RLN71018.1 - 6.7e-05 23.2 0.0 0.32 11.5 0.0 5.6 6 0 0 6 6 6 1 Ankyrin repeat Ig_3 PF13927.6 RLN71018.1 - 0.00026 21.5 0.0 0.26 11.9 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain DUF249 PF03158.13 RLN71018.1 - 0.002 17.9 0.0 1.6 8.4 0.0 2.5 2 1 0 2 2 2 2 Multigene family 530 protein Cgr1 PF03879.14 RLN71019.1 - 3e-14 53.3 19.7 4e-14 52.9 19.7 1.2 1 0 0 1 1 1 1 Cgr1 family Ten1_2 PF15490.6 RLN71020.1 - 1.4e-08 34.4 0.1 1.2e-07 31.4 0.1 1.9 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit HOOK PF05622.12 RLN71021.1 - 5.9e-25 87.5 35.5 6.4e-22 77.5 21.4 2.2 2 0 0 2 2 2 2 HOOK protein TPR_MLP1_2 PF07926.12 RLN71021.1 - 0.0002 21.4 10.0 0.0002 21.4 10.0 4.6 3 2 1 4 4 4 1 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 RLN71021.1 - 0.0031 17.6 12.2 0.0031 17.6 12.2 3.7 3 1 0 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3138 PF11336.8 RLN71021.1 - 0.042 12.5 7.0 0.13 10.8 0.3 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3138) GAS PF13851.6 RLN71021.1 - 0.22 10.8 39.5 0.24 10.7 1.8 4.4 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding HSBP1 PF06825.12 RLN71021.1 - 0.55 10.1 0.1 0.55 10.1 0.1 3.4 6 0 0 6 6 6 0 Heat shock factor binding protein 1 FAM76 PF16046.5 RLN71021.1 - 0.67 9.3 22.5 0.032 13.6 6.5 2.5 2 1 0 2 2 2 0 FAM76 protein DUF1664 PF07889.12 RLN71021.1 - 1.5 8.9 21.6 8 6.5 0.3 4.4 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) Pox_A_type_inc PF04508.12 RLN71021.1 - 2.1 8.3 7.3 1.8 8.5 0.2 4.5 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Golgin_A5 PF09787.9 RLN71021.1 - 4.4 6.7 34.1 0.79 9.1 4.1 3.5 3 1 0 3 3 3 0 Golgin subfamily A member 5 CAP PF00188.26 RLN71030.1 - 3.6e-32 111.8 12.8 4.2e-19 69.6 4.0 2.4 2 0 0 2 2 2 2 Cysteine-rich secretory protein family CW_7 PF08230.11 RLN71030.1 - 0.00058 19.6 0.0 1.9 8.3 0.0 2.6 2 0 0 2 2 2 2 CW_7 repeat DUF3394 PF11874.8 RLN71030.1 - 0.0024 17.6 0.0 2.2 7.9 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3394) Imm51 PF15595.6 RLN71030.1 - 0.05 13.5 0.4 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Immunity protein 51 Chorismate_synt PF01264.21 RLN71030.1 - 0.14 10.8 2.1 5.1 5.7 0.1 2.1 2 0 0 2 2 2 0 Chorismate synthase CAP PF00188.26 RLN71031.1 - 3e-19 70.1 3.2 3.7e-19 69.8 3.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Adeno_PIX PF03955.14 RLN71031.1 - 0.55 10.4 4.2 5.3 7.3 0.1 2.3 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) CAP PF00188.26 RLN71032.1 - 3.9e-20 72.9 2.5 7.7e-20 72.0 2.5 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family EVI2A PF05399.11 RLN71032.1 - 0.21 11.1 2.5 0.34 10.5 2.5 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) MGC-24 PF05283.11 RLN71032.1 - 5.4 7.5 6.7 11 6.5 6.7 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TPR_1 PF00515.28 RLN71035.1 - 1.9e-45 150.9 42.2 3.8e-06 26.5 1.4 15.9 16 0 0 16 16 16 11 Tetratricopeptide repeat TPR_2 PF07719.17 RLN71035.1 - 4.7e-36 120.0 58.7 5.1e-05 23.1 0.1 16.0 18 0 0 18 18 17 9 Tetratricopeptide repeat TPR_11 PF13414.6 RLN71035.1 - 2.1e-35 120.1 16.9 8.9e-06 25.3 0.0 11.1 9 3 5 14 14 14 8 TPR repeat TPR_17 PF13431.6 RLN71035.1 - 2.3e-19 68.3 23.6 0.015 15.6 0.2 11.2 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.6 RLN71035.1 - 2.9e-19 67.6 18.5 0.027 14.7 0.0 11.4 13 0 0 13 13 11 5 Tetratricopeptide repeat TPR_16 PF13432.6 RLN71035.1 - 4.3e-18 65.7 62.1 4.5e-06 27.2 0.0 9.2 6 3 2 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 RLN71035.1 - 3.8e-14 52.7 55.6 5.5e-07 29.8 0.2 10.5 7 3 3 10 10 10 6 Tetratricopeptide repeat TPR_9 PF13371.6 RLN71035.1 - 3.6e-12 46.3 54.6 0.00054 20.0 0.7 10.2 6 3 4 10 10 10 6 Tetratricopeptide repeat TPR_6 PF13174.6 RLN71035.1 - 5.2e-10 39.3 31.7 0.36 11.6 0.0 11.7 13 0 0 13 13 13 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN71035.1 - 1.5e-08 34.7 20.4 0.024 14.9 0.4 6.5 5 1 2 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 RLN71035.1 - 1e-06 29.2 31.4 0.0013 19.2 0.0 7.7 7 3 0 7 7 6 2 Tetratricopeptide repeat NARP1 PF12569.8 RLN71035.1 - 1.1e-06 27.8 2.9 0.19 10.6 0.5 4.9 4 1 1 5 5 5 2 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 RLN71035.1 - 2.5e-06 27.9 56.4 0.037 14.8 0.4 12.8 6 4 9 15 15 15 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN71035.1 - 6e-06 25.9 35.3 0.04 14.0 0.0 9.8 12 0 0 12 12 9 4 Tetratricopeptide repeat TPR_15 PF13429.6 RLN71035.1 - 5.9e-05 22.4 10.4 0.69 9.1 0.1 5.2 4 2 2 6 6 6 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN71035.1 - 0.0038 17.3 0.4 14 5.9 0.0 4.3 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 RLN71035.1 - 0.012 15.9 12.5 0.36 11.2 0.2 5.3 4 1 2 6 6 6 0 Tetratricopeptide repeat PaREP1 PF05942.11 RLN71035.1 - 0.019 14.9 1.2 2 8.4 0.2 2.6 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family BTAD PF03704.17 RLN71035.1 - 0.13 12.7 0.2 0.13 12.7 0.2 5.3 4 1 0 4 4 4 0 Bacterial transcriptional activator domain TPR_4 PF07721.14 RLN71035.1 - 0.46 11.3 36.9 0.23 12.2 0.9 7.6 7 0 0 7 7 5 0 Tetratricopeptide repeat mRNA_cap_enzyme PF01331.19 RLN71037.1 - 4.6e-25 88.6 0.1 5.9e-25 88.2 0.1 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.21 RLN71037.1 - 2e-08 34.2 0.1 2.3e-08 33.9 0.1 1.1 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DUF1930 PF09122.10 RLN71037.1 - 0.13 12.2 0.0 2.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1930) tRNA_synthFbeta PF17759.1 RLN71038.1 - 1.3e-48 165.3 0.0 1.4e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B5 PF03484.15 RLN71038.1 - 7.9e-05 22.9 0.1 0.00034 20.9 0.1 2.1 2 1 0 2 2 2 1 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 RLN71038.1 - 0.076 12.5 0.0 3.1 7.2 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DUF1179 PF06678.11 RLN71039.1 - 0.1 12.6 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) Sugar_tr PF00083.24 RLN71042.1 - 4.4e-34 118.1 8.4 5.1e-34 117.9 8.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN71042.1 - 6.1e-16 58.3 11.6 6.6e-16 58.2 11.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CytB6-F_Fe-S PF08802.10 RLN71042.1 - 0.0037 17.3 2.6 1 9.4 0.2 2.6 2 0 0 2 2 2 2 Cytochrome B6-F complex Fe-S subunit TRI12 PF06609.13 RLN71042.1 - 0.0079 14.7 4.7 0.01 14.3 4.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cytochrom_B558a PF05038.13 RLN71042.1 - 0.23 11.0 1.8 0.5 9.9 1.8 1.5 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Bacteriocin_IIc PF10439.9 RLN71042.1 - 0.73 10.0 5.6 0.19 11.8 1.6 2.0 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide BT1 PF03092.16 RLN71045.1 - 1.1e-05 23.9 3.3 0.00017 20.0 0.2 2.8 3 0 0 3 3 3 2 BT1 family SKN1 PF03935.15 RLN71046.1 - 4.5e-59 200.2 20.7 2e-37 128.8 8.2 4.9 2 2 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.15 RLN71047.1 - 1.8e-60 204.8 15.3 1.2e-39 136.1 8.7 4.7 2 2 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Acyltransferase PF01553.21 RLN71048.1 - 1.1e-17 63.9 0.0 3.1e-17 62.5 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase Acyltransf_C PF16076.5 RLN71048.1 - 1.8e-14 53.6 0.3 3e-14 52.8 0.3 1.3 1 0 0 1 1 1 1 Acyltransferase C-terminus RUN PF02759.19 RLN71048.1 - 0.033 14.2 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 RUN domain BT1 PF03092.16 RLN71049.1 - 2.2e-05 22.9 6.9 2.2e-05 22.9 6.9 2.6 2 1 1 3 3 3 2 BT1 family DUF5592 PF17332.2 RLN71049.1 - 6.1 7.5 7.1 43 4.8 1.6 3.3 2 0 0 2 2 2 0 Family of unknown function (DUF5592) IQ PF00612.27 RLN71050.1 - 0.0012 18.4 0.6 0.0012 18.4 0.6 3.8 3 0 0 3 3 3 2 IQ calmodulin-binding motif IATP PF04568.12 RLN71050.1 - 0.0022 18.4 3.5 0.0022 18.4 3.5 2.8 1 1 1 2 2 2 1 Mitochondrial ATPase inhibitor, IATP SKN1 PF03935.15 RLN71052.1 - 6.5e-58 196.3 25.1 8.6e-38 130.0 10.5 4.8 1 1 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.15 RLN71053.1 - 3.7e-14 52.0 0.3 4.4e-14 51.8 0.3 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) MnmE_helical PF12631.7 RLN71054.1 - 4.1 7.5 12.0 1.5 8.9 8.3 2.1 2 0 0 2 2 2 0 MnmE helical domain DUF1664 PF07889.12 RLN71054.1 - 9.9 6.2 6.3 8.3 6.5 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ELMO_CED12 PF04727.13 RLN71055.1 - 1.4e-25 90.4 0.0 2.1e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family UBM PF14377.6 RLN71055.1 - 8e-06 25.1 0.1 1.7e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin binding region zf-RanBP PF00641.18 RLN71055.1 - 5e-05 22.5 1.0 0.00011 21.4 1.0 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others TP2 PF01254.18 RLN71055.1 - 1.4 9.6 6.5 0.36 11.4 3.4 1.5 2 0 0 2 2 2 0 Nuclear transition protein 2 SKN1 PF03935.15 RLN71056.1 - 5.1e-59 200.0 17.7 1.1e-37 129.6 9.3 4.9 2 2 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) EB PF01683.18 RLN71056.1 - 1.8 8.9 7.3 1 9.7 3.7 2.6 2 1 0 2 2 2 0 EB module Nodulin_late PF07127.11 RLN71056.1 - 3.4 8.1 5.1 2.4 8.6 0.4 2.9 3 0 0 3 3 3 0 Late nodulin protein SKN1 PF03935.15 RLN71057.1 - 2.5e-59 201.0 18.0 3.7e-38 131.2 8.3 4.6 1 1 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) PG_isomerase_N PF18353.1 RLN71057.1 - 0.039 14.3 0.0 0.088 13.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoglucose isomerase N-terminal domain AIF_C PF14721.6 RLN71057.1 - 0.14 12.5 0.1 0.24 11.7 0.1 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term EB PF01683.18 RLN71057.1 - 3.3 8.1 9.8 0.15 12.3 2.0 2.8 3 0 0 3 3 3 0 EB module Ank_2 PF12796.7 RLN71074.1 - 1.9e-20 73.2 4.1 2.7e-10 40.7 0.6 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN71074.1 - 1.5e-19 69.8 5.2 0.0011 19.3 0.0 6.0 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN71074.1 - 3.4e-19 68.9 3.4 1.2e-06 28.9 0.5 3.8 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN71074.1 - 2.5e-10 39.7 0.1 1.3 9.9 0.1 5.6 5 1 1 6 6 6 3 Ankyrin repeat DUF5049 PF16468.5 RLN71074.1 - 0.00027 20.8 0.0 5.8 6.9 0.0 4.6 2 2 4 6 6 6 1 Domain of unknown function (DUF5049) Ank PF00023.30 RLN71074.1 - 0.00067 20.0 0.2 7.5 7.2 0.1 4.9 2 2 1 3 3 3 1 Ankyrin repeat DUF3322 PF11795.8 RLN71074.1 - 0.019 15.0 1.0 0.29 11.1 0.1 2.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) DUF1843 PF08898.10 RLN71074.1 - 0.2 12.2 7.6 52 4.5 0.0 4.9 6 0 0 6 6 6 0 Domain of unknown function (DUF1843) DUF4287 PF14117.6 RLN71074.1 - 1.3 9.2 7.6 2.6 8.3 0.3 4.3 4 1 1 5 5 5 0 Domain of unknown function (DUF4287) DUF1987 PF09345.10 RLN71074.1 - 1.4 8.6 3.1 26 4.5 0.0 3.5 2 1 1 4 4 4 0 Domain of unknown function (DUF1987) Ank_4 PF13637.6 RLN71075.1 - 4.7e-39 132.3 26.4 1.9e-06 28.3 0.1 11.6 7 3 5 12 12 12 10 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN71075.1 - 4.8e-35 120.0 9.0 2.1e-07 31.5 0.1 7.5 1 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN71075.1 - 1.9e-25 88.6 29.3 0.053 13.9 0.1 14.7 4 3 12 16 16 16 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN71075.1 - 1.5e-17 61.9 10.4 9.2 7.2 0.0 14.6 14 1 2 16 16 16 3 Ankyrin repeat Ank PF00023.30 RLN71075.1 - 2.6e-06 27.6 1.4 88 3.8 0.0 9.2 5 3 3 8 8 8 0 Ankyrin repeat HA PF03457.14 RLN71075.1 - 2.9e-05 24.3 0.9 1.2 9.5 0.0 6.1 3 2 1 4 4 4 1 Helicase associated domain DUF1843 PF08898.10 RLN71075.1 - 0.00063 20.2 17.7 5.1 7.7 0.2 9.2 11 0 0 11 11 11 1 Domain of unknown function (DUF1843) AbiEi_3_N PF17194.4 RLN71075.1 - 0.02 14.9 0.3 6.5 6.9 0.0 4.9 5 1 2 7 7 7 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain MtN3_slv PF03083.16 RLN71076.1 - 4.1e-89 292.7 59.3 3.2e-23 81.6 1.8 6.7 7 0 0 7 7 7 6 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RLN71076.1 - 0.0084 15.9 24.5 0.28 11.0 0.5 6.9 6 0 0 6 6 6 2 PQ loop repeat YmcE_antitoxin PF15939.5 RLN71076.1 - 0.35 11.1 4.0 11 6.3 0.5 2.8 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system Syndecan PF01034.20 RLN71076.1 - 3.2 7.7 0.0 3.2 7.7 0.0 5.3 6 0 0 6 6 6 0 Syndecan domain Cytochrom_B_C PF00032.17 RLN71076.1 - 5.1 7.4 37.3 3.3 8.0 0.4 7.2 5 3 3 8 8 8 0 Cytochrome b(C-terminal)/b6/petD PAP_assoc PF03828.19 RLN71077.1 - 5.6e-16 58.5 0.0 1.3e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase zf-CCHC PF00098.23 RLN71077.1 - 0.0011 19.0 2.4 0.0011 19.0 2.4 2.8 3 0 0 3 3 3 2 Zinc knuckle Nrap_D2 PF17403.2 RLN71077.1 - 0.02 14.6 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain zf-C2H2_10 PF16588.5 RLN71077.1 - 0.062 13.0 0.5 0.17 11.7 0.5 1.7 1 0 0 1 1 1 0 C2H2 zinc-finger NTP_transf_2 PF01909.23 RLN71077.1 - 0.069 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain GTP1_OBG PF01018.22 RLN71127.1 - 2.5e-31 108.4 9.7 6.2e-15 55.1 7.2 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 RLN71127.1 - 7.3e-18 64.7 0.0 2.6e-17 62.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN71127.1 - 2.9e-06 26.9 0.0 4.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 RLN71127.1 - 0.048 14.2 0.0 0.097 13.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Sigma70_ner PF04546.13 RLN71127.1 - 0.07 13.0 4.8 0.12 12.2 4.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region YL1 PF05764.13 RLN71127.1 - 0.1 12.7 9.2 0.15 12.1 9.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein AAA_18 PF13238.6 RLN71127.1 - 0.15 12.6 0.5 0.57 10.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain Cwf_Cwc_15 PF04889.12 RLN71127.1 - 0.25 11.0 15.7 0.41 10.3 15.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 RLN71127.1 - 0.33 9.2 8.7 0.45 8.7 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RLN71127.1 - 0.57 8.3 11.2 0.75 7.9 11.2 1.0 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 RLN71127.1 - 2.9 7.9 5.8 5 7.1 5.8 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal SDA1 PF05285.12 RLN71127.1 - 5.6 6.3 15.8 8 5.8 15.8 1.1 1 0 0 1 1 1 0 SDA1 Ank_2 PF12796.7 RLN71128.1 - 6e-30 103.7 1.6 2.7e-08 34.3 0.0 4.6 2 1 5 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN71128.1 - 1.9e-23 82.5 4.0 8.6e-06 26.2 0.0 7.5 3 1 5 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN71128.1 - 4.6e-22 77.8 0.4 3.9e-07 30.2 0.1 5.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN71128.1 - 8.5e-18 63.9 5.1 0.00032 21.0 0.2 7.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 RLN71128.1 - 1.6e-14 52.6 1.0 0.092 13.4 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat PH PF00169.29 RLN71128.1 - 1.2e-11 45.0 0.5 2.5e-11 44.0 0.5 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN71128.1 - 4.2e-05 23.9 1.0 0.00017 22.0 0.7 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 RLN71128.1 - 0.00015 21.9 0.2 0.0005 20.3 0.2 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain VPS9 PF02204.18 RLN71128.1 - 0.058 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 9 (VPS9) domain PDZ PF00595.24 RLN71128.1 - 0.15 12.5 0.1 0.43 11.0 0.1 1.8 2 0 0 2 2 2 0 PDZ domain Beta-Casp PF10996.8 RLN71129.1 - 3.3e-08 33.8 0.0 8e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 RLN71129.1 - 4.1e-07 29.6 0.0 7.8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain AfsA PF03756.13 RLN71129.1 - 0.05 13.6 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 A-factor biosynthesis hotdog domain Helicase_C_2 PF13307.6 RLN71130.1 - 2.5e-52 177.5 0.1 6.5e-40 137.1 0.0 2.5 2 0 0 2 2 2 2 Helicase C-terminal domain DEAD_2 PF06733.15 RLN71130.1 - 2.2e-51 174.0 0.3 3.5e-51 173.3 0.3 1.4 1 0 0 1 1 1 1 DEAD_2 Ank_2 PF12796.7 RLN71131.1 - 3.1e-16 59.7 0.7 7.2e-14 52.1 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN71131.1 - 4.8e-16 58.6 1.1 9.7e-11 41.7 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN71131.1 - 3.4e-15 55.7 2.2 1.1e-09 38.3 0.5 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 RLN71131.1 - 8e-15 53.5 0.8 6.9e-06 26.0 0.2 4.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 RLN71131.1 - 3.7e-14 52.9 0.8 6.9e-13 48.8 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) TPR_1 PF00515.28 RLN71132.1 - 2.5e-42 141.0 0.7 3.1e-09 36.2 0.3 9.8 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 RLN71132.1 - 9.8e-40 131.5 5.3 6.8e-07 28.9 0.5 11.2 11 0 0 11 11 10 5 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN71132.1 - 2e-30 104.9 8.9 1.2e-18 67.1 0.1 5.8 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 RLN71132.1 - 6.9e-26 90.6 3.4 9.7e-09 35.7 0.0 8.4 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 RLN71132.1 - 3.2e-25 86.2 0.0 0.0019 18.3 0.0 8.7 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 RLN71132.1 - 1e-24 86.8 6.2 0.002 18.6 0.0 9.3 4 2 6 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 RLN71132.1 - 4.1e-22 78.3 13.4 8.8e-05 22.7 0.2 9.2 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 RLN71132.1 - 1.4e-19 69.4 0.2 2.8e-08 33.3 0.3 6.9 4 1 4 8 8 8 4 TPR repeat TPR_14 PF13428.6 RLN71132.1 - 4e-18 64.6 15.2 0.058 14.2 0.0 12.3 7 2 6 13 13 11 4 Tetratricopeptide repeat TPR_17 PF13431.6 RLN71132.1 - 5.2e-17 60.9 1.2 0.0057 16.9 0.0 8.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN71132.1 - 1.4e-12 46.7 5.3 0.42 10.8 0.0 8.7 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 RLN71132.1 - 5e-11 42.5 5.8 7.8 7.4 0.0 10.5 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_9 PF13371.6 RLN71132.1 - 1.9e-09 37.5 0.2 0.00049 20.2 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat Ank_2 PF12796.7 RLN71132.1 - 1.6e-08 35.0 0.0 4.6e-05 23.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN71132.1 - 1.8e-05 24.9 0.8 1.8 9.0 0.1 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) TPR_15 PF13429.6 RLN71132.1 - 7.7e-05 22.0 1.5 0.094 11.9 0.0 4.6 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 RLN71132.1 - 0.00083 19.6 1.6 0.064 13.6 0.2 4.3 3 2 1 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN71132.1 - 0.00089 19.0 3.3 42 4.2 0.0 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_21 PF09976.9 RLN71132.1 - 0.0013 18.5 0.1 0.092 12.4 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat-like domain Ank_3 PF13606.6 RLN71132.1 - 0.0018 18.6 0.2 1.8 9.4 0.0 3.9 4 0 0 4 4 2 1 Ankyrin repeat TPR_4 PF07721.14 RLN71132.1 - 0.0022 18.4 10.3 1.9 9.4 0.0 7.2 6 0 0 6 6 5 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 RLN71132.1 - 0.0034 17.0 0.0 0.06 13.0 0.0 2.9 3 0 0 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) Ank PF00023.30 RLN71132.1 - 0.0069 16.8 0.1 12 6.6 0.0 3.2 3 0 0 3 3 2 0 Ankyrin repeat 2OG-FeII_Oxy_3 PF13640.6 RLN71132.1 - 0.012 16.5 0.1 0.051 14.5 0.0 2.2 2 0 0 2 2 1 0 2OG-Fe(II) oxygenase superfamily ChAPs PF09295.10 RLN71132.1 - 0.017 14.1 0.3 4.7 6.1 0.0 3.3 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Ank_4 PF13637.6 RLN71132.1 - 0.06 13.9 0.4 12 6.6 0.1 3.6 3 1 0 3 3 3 0 Ankyrin repeats (many copies) TPR_3 PF07720.12 RLN71132.1 - 7.1 6.7 9.1 26 4.9 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat FoP_duplication PF13865.6 RLN71133.1 - 4e-19 68.9 8.7 4e-19 68.9 8.7 3.4 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Paramyxo_ncap PF00973.19 RLN71133.1 - 1.3 7.9 5.4 1.6 7.5 5.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Presenilin PF01080.17 RLN71133.1 - 2.2 7.0 6.7 2.7 6.7 6.7 1.2 1 0 0 1 1 1 0 Presenilin MORN PF02493.20 RLN71135.1 - 5.9e-40 132.8 66.2 1.4e-06 27.8 0.2 12.7 13 1 0 13 13 13 10 MORN repeat NOA36 PF06524.12 RLN71136.1 - 2.4 7.4 6.5 6.7 5.9 6.5 1.7 1 0 0 1 1 1 0 NOA36 protein DUF4602 PF15375.6 RLN71137.1 - 6.3e-15 55.7 6.6 8.9e-14 52.0 6.6 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) EMP24_GP25L PF01105.24 RLN71138.1 - 9.7e-19 68.0 0.9 1.4e-18 67.4 0.9 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DEAD PF00270.29 RLN71139.1 - 9.6e-46 155.7 0.3 3.9e-44 150.5 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN71139.1 - 6.4e-18 65.1 0.0 3.9e-17 62.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN71139.1 - 8.5e-07 29.1 0.0 2.7e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RLN71139.1 - 0.086 13.1 0.2 0.26 11.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain DUF4217 PF13959.6 RLN71139.1 - 0.16 12.2 0.0 0.73 10.1 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) Clathrin PF00637.20 RLN71140.1 - 9.2e-10 38.6 11.1 0.12 12.3 0.1 6.6 3 1 4 7 7 7 2 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 RLN71140.1 - 9.8e-09 35.4 0.3 0.018 15.4 0.0 5.5 6 0 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_14 PF13428.6 RLN71140.1 - 2.8e-08 33.9 26.7 0.0051 17.5 0.0 9.7 10 1 0 10 10 9 2 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 RLN71140.1 - 3.3e-07 29.7 6.7 0.056 12.5 0.6 4.2 5 0 0 5 5 5 3 Coatomer WD associated region SNAP PF14938.6 RLN71140.1 - 6.9e-07 29.0 28.5 0.0019 17.7 6.3 4.7 3 1 1 4 4 4 2 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 RLN71140.1 - 8.2e-07 28.6 22.1 0.0091 16.0 0.2 8.6 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN71140.1 - 1e-05 25.3 29.5 0.039 14.1 0.5 9.9 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN71140.1 - 0.0008 19.0 11.1 0.74 9.6 0.2 5.3 6 0 0 6 6 6 2 TPR repeat TPR_8 PF13181.6 RLN71140.1 - 0.0013 18.8 20.1 0.032 14.4 0.4 8.1 10 1 1 11 11 9 1 Tetratricopeptide repeat WD40 PF00400.32 RLN71140.1 - 0.0022 18.8 0.2 5.9 7.9 0.0 5.6 6 0 0 6 6 6 1 WD domain, G-beta repeat TPR_12 PF13424.6 RLN71140.1 - 0.0041 17.4 25.6 0.0043 17.3 2.2 7.1 8 1 0 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN71140.1 - 0.0049 17.3 28.4 11 6.7 0.2 9.9 7 3 4 11 11 11 0 Tetratricopeptide repeat Vps39_1 PF10366.9 RLN71140.1 - 0.013 15.8 1.3 0.21 11.9 0.1 3.3 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 RPN7 PF10602.9 RLN71140.1 - 0.017 14.8 17.7 0.067 12.9 0.1 6.5 5 2 1 6 6 6 0 26S proteasome subunit RPN7 TPR_1 PF00515.28 RLN71140.1 - 0.36 10.7 31.6 1 9.3 0.1 8.2 8 0 0 8 8 8 0 Tetratricopeptide repeat PPR PF01535.20 RLN71140.1 - 0.81 10.1 9.8 15 6.1 0.2 5.8 7 0 0 7 7 5 0 PPR repeat PPR_2 PF13041.6 RLN71140.1 - 0.91 9.8 5.7 1.4 9.2 0.2 4.1 4 0 0 4 4 4 0 PPR repeat family ANAPC3 PF12895.7 RLN71140.1 - 1.7 8.9 22.0 2.6 8.3 0.3 7.3 5 3 1 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 RLN71140.1 - 2.7 8.0 14.9 0.83 9.6 0.6 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN71140.1 - 5.3 7.9 29.1 6.1 7.7 0.1 8.4 9 0 0 9 9 7 0 Tetratricopeptide repeat IQ PF00612.27 RLN71141.1 - 3.3e-10 38.8 19.2 0.0019 17.9 2.0 4.9 4 0 0 4 4 4 4 IQ calmodulin-binding motif DUF2752 PF10825.8 RLN71141.1 - 0.14 12.2 0.9 0.27 11.3 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) RCC1 PF00415.18 RLN71142.1 - 1.8e-86 284.6 25.7 5.6e-15 55.7 0.6 7.8 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN71142.1 - 3.7e-42 141.3 52.5 9.2e-10 38.1 2.9 8.7 8 1 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat DUF1924 PF09086.11 RLN71142.1 - 0.0044 17.4 0.3 20 5.6 0.0 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF1924) PapC_C PF13953.6 RLN71142.1 - 0.022 14.6 0.2 22 4.9 0.0 3.4 3 0 0 3 3 3 0 PapC C-terminal domain DUF1921 PF09081.10 RLN71142.1 - 0.022 15.0 1.3 0.25 11.6 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1921) SUKH-3 PF14433.6 RLN71142.1 - 0.024 15.1 1.4 32 5.0 0.0 4.2 3 2 2 5 5 5 0 SUKH-3 immunity protein Hira PF07569.11 RLN71142.1 - 0.09 12.5 5.3 16 5.1 0.3 3.8 5 0 0 5 5 5 0 TUP1-like enhancer of split Zn_Tnp_IS1 PF03811.13 RLN71142.1 - 0.12 12.2 2.0 0.31 10.8 0.1 2.7 3 0 0 3 3 3 0 InsA N-terminal domain Peptidase_C69 PF03577.15 RLN71144.1 - 2.7e-54 184.6 0.0 7.9e-54 183.1 0.0 1.8 1 1 0 1 1 1 1 Peptidase family C69 HSF_DNA-bind PF00447.17 RLN71145.1 - 4.7e-21 75.2 3.4 7e-21 74.7 3.4 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding DUF755 PF05501.11 RLN71145.1 - 0.00086 19.6 8.9 0.0015 18.8 8.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF755) IMUP PF15761.5 RLN71145.1 - 0.036 14.7 7.3 0.068 13.9 7.3 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 RLN71145.1 - 0.2 11.3 10.4 0.32 10.6 10.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SUZ PF12752.7 RLN71145.1 - 0.77 10.6 4.9 9.1 7.1 5.0 2.3 2 0 0 2 2 2 0 SUZ domain Ank_2 PF12796.7 RLN71146.1 - 2.3e-14 53.7 1.0 1e-07 32.4 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN71146.1 - 9.4e-11 42.0 0.9 0.0019 18.7 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN71146.1 - 2.5e-10 40.3 3.7 0.0002 21.6 0.1 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 RLN71146.1 - 1.4e-07 31.6 0.5 3.4e-06 27.2 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN71146.1 - 3.8e-06 26.8 3.2 0.79 10.5 0.3 4.4 4 1 0 4 4 4 2 Ankyrin repeat PsbH PF00737.20 RLN71146.1 - 0.1 12.4 0.7 4.6 7.0 0.1 2.6 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein DUF4231 PF14015.6 RLN71146.1 - 0.37 11.3 4.6 0.36 11.3 2.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) CPL PF08144.11 RLN71147.1 - 2.5e-16 60.3 5.0 4.9e-12 46.4 0.1 4.9 3 3 2 5 5 5 2 CPL (NUC119) domain PUF PF00806.19 RLN71147.1 - 3.9e-09 35.7 0.3 0.00067 19.2 0.0 5.3 5 0 0 5 5 5 2 Pumilio-family RNA binding repeat DUF4071 PF13281.6 RLN71147.1 - 0.0042 16.2 3.0 0.0044 16.1 1.6 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4071) PHD_like PF12910.7 RLN71147.1 - 0.13 12.3 0.4 2.4 8.2 0.0 2.6 2 1 1 3 3 3 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system RasGAP PF00616.19 RLN71148.1 - 6.6e-23 81.5 0.0 2.1e-19 70.1 0.0 3.2 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase PH PF00169.29 RLN71148.1 - 0.00032 21.2 0.0 0.0009 19.7 0.0 1.7 1 0 0 1 1 1 1 PH domain HABP4_PAI-RBP1 PF04774.15 RLN71149.1 - 1.8e-13 51.3 11.3 8.7e-13 49.1 11.3 2.2 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family EXOSC1 PF10447.9 RLN71150.1 - 0.067 13.8 1.1 0.12 13.0 1.1 1.4 1 0 0 1 1 1 0 Exosome component EXOSC1/CSL4 Ribosomal_L6e PF01159.19 RLN71151.1 - 7.9e-33 113.3 4.9 2.1e-32 111.9 2.0 2.6 2 1 0 2 2 2 1 Ribosomal protein L6e Pkinase PF00069.25 RLN71152.1 - 1.1e-69 234.8 0.0 6.2e-69 232.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN71152.1 - 1.4e-27 96.7 0.0 2e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 RLN71152.1 - 0.15 11.0 0.3 0.29 10.1 0.0 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase LRR_6 PF13516.6 RLN71153.1 - 1e-17 62.6 6.0 2.5e-05 24.0 0.1 5.3 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 RLN71153.1 - 0.0054 17.1 0.9 63 4.7 0.1 4.3 4 1 0 4 4 4 1 Leucine Rich Repeat Pkinase PF00069.25 RLN71154.1 - 2e-35 122.4 0.0 2.6e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN71154.1 - 5.9e-17 61.8 0.0 7.7e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN71154.1 - 6e-06 25.8 0.0 8.6e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like MetW PF07021.12 RLN71154.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FAP206 PF12018.8 RLN71155.1 - 3e-08 33.5 1.1 0.0088 15.6 0.0 4.4 5 0 0 5 5 5 2 Domain of unknown function AAA PF00004.29 RLN71155.1 - 1.8e-06 28.4 0.0 0.044 14.2 0.0 3.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN71155.1 - 2.7e-06 27.7 0.0 1.3 9.3 0.0 3.8 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 RLN71155.1 - 2.7e-05 24.7 0.0 0.15 12.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain YHS PF04945.13 RLN71155.1 - 0.00018 21.6 1.0 0.38 10.9 0.8 4.5 5 0 0 5 5 5 1 YHS domain AAA_33 PF13671.6 RLN71155.1 - 0.00031 20.9 3.8 0.36 11.0 0.0 3.9 4 0 0 4 4 4 2 AAA domain Hydin_ADK PF17213.3 RLN71155.1 - 0.001 19.4 6.8 0.032 14.5 0.0 3.9 4 0 0 4 4 4 2 Hydin Adenylate kinase-like domain IstB_IS21 PF01695.17 RLN71155.1 - 0.0011 18.7 0.0 0.7 9.6 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_5 PF07728.14 RLN71155.1 - 0.0052 16.8 0.0 14 5.6 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RLN71155.1 - 0.008 16.6 30.6 0.07 13.5 0.2 5.8 5 3 1 6 6 5 3 AAA ATPase domain AAA_17 PF13207.6 RLN71155.1 - 0.0082 16.6 0.0 2.4 8.6 0.0 3.3 3 0 0 3 3 2 1 AAA domain SKI PF01202.22 RLN71155.1 - 0.073 13.2 0.6 13 5.9 0.0 3.6 3 1 0 3 3 3 0 Shikimate kinase KTI12 PF08433.10 RLN71155.1 - 0.11 11.9 0.0 7 6.0 0.0 2.8 3 0 0 3 3 3 0 Chromatin associated protein KTI12 RNA_helicase PF00910.22 RLN71155.1 - 0.22 11.9 0.0 4.1 7.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 RLN71155.1 - 1.6 8.9 15.2 0.45 10.7 0.0 4.6 4 1 0 4 4 3 0 AAA domain Hydrolase PF00702.26 RLN71156.1 - 1.9e-40 139.4 1.7 3.2e-40 138.7 1.7 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RLN71156.1 - 1.2e-39 135.7 2.3 3.1e-39 134.4 2.3 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 RLN71156.1 - 5.8e-10 39.5 0.0 3.9e-08 33.6 0.0 3.1 2 1 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 RLN71156.1 - 6.2e-06 26.1 0.0 0.0011 18.7 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 RLN71156.1 - 0.00052 20.5 0.1 0.0016 18.9 0.1 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3090 PF11290.8 RLN71157.1 - 0.0042 16.9 0.2 0.01 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3090) DEAD PF00270.29 RLN71158.1 - 2.1e-45 154.6 0.0 5e-45 153.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN71158.1 - 6.3e-17 61.9 0.0 3.9e-16 59.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN71158.1 - 8.2e-08 32.4 0.0 2.5e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 RLN71158.1 - 0.0013 18.0 0.0 0.002 17.5 0.0 1.5 1 1 0 1 1 1 1 SecA DEAD-like domain DUF4217 PF13959.6 RLN71158.1 - 0.017 15.4 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) AAA_22 PF13401.6 RLN71158.1 - 0.15 12.4 0.1 3.4 7.9 0.0 2.8 2 1 1 3 3 3 0 AAA domain Nop PF01798.18 RLN71159.1 - 2e-67 227.0 0.0 3.4e-67 226.3 0.0 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 RLN71159.1 - 2e-36 125.5 3.8 5.6e-36 124.1 3.8 1.8 1 0 0 1 1 1 1 Prp31 C terminal domain 2OG-FeII_Oxy PF03171.20 RLN71160.1 - 2e-06 28.2 0.1 8.5e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily RIG-I_C PF18119.1 RLN71162.1 - 0.045 13.8 0.1 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 RIG-I receptor C-terminal domain DUF4515 PF14988.6 RLN71165.1 - 0.026 14.3 0.6 0.026 14.3 0.6 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4515) Nup54 PF13874.6 RLN71165.1 - 4.6 7.3 12.3 6.6 6.8 3.2 4.0 3 1 0 3 3 3 0 Nucleoporin complex subunit 54 DUF2139 PF09910.9 RLN71166.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2139) Arm PF00514.23 RLN71167.1 - 7.4e-57 187.8 31.6 8.8e-05 22.4 0.1 13.8 14 0 0 14 14 14 12 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 RLN71167.1 - 1.9e-10 40.6 0.8 0.0085 15.6 0.0 5.7 2 1 0 3 3 3 3 Armadillo-like Atx10homo_assoc PF09759.9 RLN71167.1 - 6.7e-06 26.1 2.9 47 4.1 0.0 6.6 5 1 1 6 6 6 0 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.8 RLN71167.1 - 2.9e-05 24.1 3.0 1.6 8.7 0.0 4.7 4 1 1 5 5 5 2 Myosin-binding striated muscle assembly central HEAT_EZ PF13513.6 RLN71167.1 - 0.00044 20.7 32.3 1.5 9.4 0.6 8.8 5 2 5 10 10 10 3 HEAT-like repeat CoA_trans PF01144.23 RLN71167.1 - 0.0026 17.2 0.8 2.2 7.6 0.1 2.4 2 0 0 2 2 2 2 Coenzyme A transferase DUF3361 PF11841.8 RLN71167.1 - 0.016 15.2 0.4 12 5.8 0.0 4.9 3 3 3 7 7 7 0 Domain of unknown function (DUF3361) Nuc_rec_co-act PF08815.10 RLN71167.1 - 0.018 14.9 0.1 20 5.1 0.0 3.5 3 0 0 3 3 3 0 Nuclear receptor coactivator DHDPS PF00701.22 RLN71169.1 - 6.3e-69 231.9 0.0 7.6e-69 231.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family HHH PF00633.23 RLN71169.1 - 0.053 13.4 0.1 0.15 12.0 0.1 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif Acetyltransf_10 PF13673.7 RLN71170.1 - 1e-09 38.4 0.1 2.2e-09 37.3 0.1 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN71170.1 - 9.6e-09 35.6 0.5 1.9e-08 34.6 0.5 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RLN71170.1 - 2.8e-06 27.5 0.1 4e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 RLN71170.1 - 0.0006 19.9 0.3 0.0044 17.1 0.3 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN71170.1 - 0.0082 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein SDA1 PF05285.12 RLN71170.1 - 0.054 12.9 0.0 0.063 12.7 0.0 1.1 1 0 0 1 1 1 0 SDA1 Acetyltransf_5 PF13444.6 RLN71170.1 - 0.093 13.5 1.8 0.37 11.5 0.8 2.0 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Bse634I PF07832.11 RLN71172.1 - 0.047 13.0 0.4 0.18 11.1 0.1 2.0 2 0 0 2 2 2 0 Cfr10I/Bse634I restriction endonuclease DUF2779 PF11074.8 RLN71173.1 - 0.093 13.2 0.1 0.12 12.8 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function(DUF2779) DUF1206 PF06724.11 RLN71176.1 - 0.017 15.2 0.7 0.048 13.7 0.7 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) Adeno_E3B PF03376.14 RLN71176.1 - 1.8 8.8 7.0 0.53 10.5 1.9 2.7 2 0 0 2 2 2 0 Adenovirus E3B protein Kinesin PF00225.23 RLN71178.1 - 1.5e-91 306.8 0.0 2.2e-91 306.3 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN71178.1 - 7.5e-17 61.6 0.0 1.2e-15 57.7 0.0 2.2 1 1 0 1 1 1 1 Microtubule binding YabA PF06156.13 RLN71178.1 - 0.022 15.4 7.3 1.1 9.9 0.0 2.8 2 1 0 2 2 2 0 Initiation control protein YabA HOOK PF05622.12 RLN71178.1 - 0.066 11.3 4.0 0.054 11.6 2.1 1.6 2 0 0 2 2 2 0 HOOK protein Vac_Fusion PF02346.16 RLN71178.1 - 0.077 12.6 0.7 0.23 11.1 0.7 1.7 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 HlyD_D23 PF16576.5 RLN71178.1 - 0.41 9.8 2.6 0.77 8.9 2.6 1.4 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion bZIP_2 PF07716.15 RLN71178.1 - 1.2 9.2 14.2 5 7.3 2.4 3.6 3 0 0 3 3 3 0 Basic region leucine zipper TSC22 PF01166.18 RLN71178.1 - 1.4 9.3 7.7 29 5.1 0.4 3.4 3 0 0 3 3 3 0 TSC-22/dip/bun family Wtap PF17098.5 RLN71178.1 - 1.5 8.7 15.1 1.4 8.8 13.5 1.7 1 1 0 1 1 1 0 WTAP/Mum2p family Shugoshin_N PF07558.11 RLN71178.1 - 2.2 8.2 5.3 16 5.4 1.1 2.6 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region OmpH PF03938.14 RLN71178.1 - 2.7 8.4 7.8 4.7 7.6 7.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MerR-DNA-bind PF09278.11 RLN71178.1 - 2.9 8.5 12.1 15 6.3 0.6 2.6 2 0 0 2 2 2 0 MerR, DNA binding Jnk-SapK_ap_N PF09744.9 RLN71178.1 - 5.2 7.3 9.6 16 5.7 9.6 1.8 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ATG16 PF08614.11 RLN71178.1 - 9.8 6.3 17.8 1.1e+02 2.9 17.5 2.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) ParcG PF10274.9 RLN71179.1 - 1.1e-52 178.8 0.0 1.4e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein Dpy-30 PF05186.13 RLN71180.1 - 2e-13 49.8 0.0 3.6e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.22 RLN71180.1 - 1.1e-06 28.9 0.0 0.28 11.3 0.0 3.3 3 0 0 3 3 3 2 Adenylate kinase AAA_17 PF13207.6 RLN71180.1 - 0.00046 20.6 0.8 0.027 14.9 0.0 3.2 2 1 1 3 3 3 1 AAA domain Hydin_ADK PF17213.3 RLN71180.1 - 0.00078 19.8 3.8 0.0043 17.4 0.0 3.1 2 1 1 3 3 3 1 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 RLN71180.1 - 0.0033 17.6 13.5 0.038 14.1 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 RLN71180.1 - 0.1 13.2 0.0 1.1 9.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RLN71180.1 - 0.16 12.2 0.0 0.16 12.2 0.0 3.2 3 2 0 3 3 3 0 AAA domain UBA2_C PF16195.5 RLN71180.1 - 7.7 7.3 16.0 0.46 11.2 1.6 3.7 3 0 0 3 3 3 0 SUMO-activating enzyme subunit 2 C-terminus FapA PF03961.13 RLN71181.1 - 0.012 14.2 6.0 0.017 13.8 6.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A KinB_sensor PF16767.5 RLN71181.1 - 0.016 15.6 6.8 0.032 14.7 6.8 1.5 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB Prominin PF05478.11 RLN71181.1 - 0.019 12.9 2.5 0.021 12.8 2.5 1.0 1 0 0 1 1 1 0 Prominin Filament PF00038.21 RLN71181.1 - 0.043 13.4 18.7 0.37 10.3 18.2 1.9 1 1 0 1 1 1 0 Intermediate filament protein DUF4407 PF14362.6 RLN71181.1 - 0.049 13.0 8.1 0.057 12.8 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SpecificRecomb PF10136.9 RLN71181.1 - 0.078 11.3 7.2 0.095 11.0 7.2 1.0 1 0 0 1 1 1 0 Site-specific recombinase TSC22 PF01166.18 RLN71181.1 - 0.21 11.9 11.0 0.37 11.1 1.1 3.0 3 0 0 3 3 3 0 TSC-22/dip/bun family MHC_II_beta PF00969.19 RLN71181.1 - 0.21 11.7 1.3 0.27 11.4 0.2 1.7 2 0 0 2 2 1 0 Class II histocompatibility antigen, beta domain HALZ PF02183.18 RLN71181.1 - 0.22 11.8 0.6 0.22 11.8 0.6 3.2 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF1664 PF07889.12 RLN71181.1 - 0.22 11.5 8.8 1.8 8.6 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SprA-related PF12118.8 RLN71181.1 - 0.25 10.5 9.9 0.32 10.1 9.9 1.1 1 0 0 1 1 1 0 SprA-related family YabA PF06156.13 RLN71181.1 - 0.33 11.6 14.8 0.85 10.3 1.4 2.9 1 1 1 2 2 2 0 Initiation control protein YabA DUF2968 PF11180.8 RLN71181.1 - 0.33 10.6 22.2 1.4 8.5 21.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) Exonuc_VII_L PF02601.15 RLN71181.1 - 0.59 9.6 10.3 0.62 9.6 10.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Noelin-1 PF12308.8 RLN71181.1 - 0.62 10.1 6.7 0.48 10.4 0.9 2.5 1 1 1 2 2 2 0 Neurogenesis glycoprotein MADF_DNA_bdg PF10545.9 RLN71181.1 - 1.3 9.4 9.7 1.4 9.3 3.8 2.3 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Cob_adeno_trans PF01923.18 RLN71181.1 - 1.4 9.0 6.0 1.8 8.7 6.0 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF4337 PF14235.6 RLN71181.1 - 1.4 9.0 13.6 0.15 12.1 8.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) AAA_11 PF13086.6 RLN71181.1 - 1.6 8.4 10.6 2.1 8.0 10.6 1.1 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.9 RLN71181.1 - 1.8 7.6 16.5 2.2 7.3 16.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 RLN71181.1 - 3 5.6 7.8 3.5 5.4 7.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Jnk-SapK_ap_N PF09744.9 RLN71181.1 - 3.4 7.9 25.4 8.2 6.6 15.8 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF1640 PF07798.11 RLN71181.1 - 4 7.4 16.2 0.68 10.0 4.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF1690 PF07956.11 RLN71181.1 - 9.8 6.6 16.3 17 5.8 16.0 1.6 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) zf-RVT PF13966.6 RLN71188.1 - 0.00069 20.3 0.5 0.0017 19.0 0.1 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase p450 PF00067.22 RLN71189.1 - 1.1e-82 278.3 0.0 1.3e-82 278.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Presenilin PF01080.17 RLN71199.1 - 0.12 11.1 2.7 0.16 10.7 2.7 1.2 1 0 0 1 1 1 0 Presenilin Aldedh PF00171.22 RLN71200.1 - 6.7e-169 562.2 0.2 8.1e-169 562.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CotH PF08757.11 RLN71201.1 - 5.1e-30 105.1 1.0 2.8e-14 53.4 0.5 2.1 2 0 0 2 2 2 2 CotH kinase protein Ion_trans PF00520.31 RLN71203.1 - 1.7e-36 125.7 60.6 1.3e-19 70.4 10.7 4.6 5 1 1 6 6 6 3 Ion transport protein DUF2198 PF09964.9 RLN71203.1 - 0.015 15.4 2.7 0.96 9.6 0.1 3.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) SK_channel PF03530.14 RLN71203.1 - 0.36 10.8 3.5 1.5 8.8 0.1 3.5 2 0 0 2 2 2 0 Calcium-activated SK potassium channel REPA_OB_2 PF16900.5 RLN71226.1 - 0.027 14.4 0.0 5.8 6.9 0.0 2.8 2 1 0 2 2 2 0 Replication protein A OB domain tRNA_anti-codon PF01336.25 RLN71226.1 - 0.14 12.2 0.0 8.1 6.5 0.0 3.1 4 0 0 4 4 4 0 OB-fold nucleic acid binding domain Pkinase PF00069.25 RLN71227.1 - 1.7e-63 214.5 0.0 2.5e-63 213.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN71227.1 - 1.6e-33 116.1 0.0 2.4e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN71227.1 - 1.2e-09 37.9 0.0 9.6e-08 31.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 RLN71227.1 - 0.0022 17.4 0.4 0.0039 16.6 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN71227.1 - 0.0026 17.7 1.1 0.1 12.5 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family DDE_3 PF13358.6 RLN71233.1 - 2.1e-11 43.7 0.0 2e-08 34.1 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease Abhydrolase_1 PF00561.20 RLN71235.1 - 3.1e-13 50.0 0.5 5.3e-10 39.4 0.2 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN71235.1 - 0.00067 20.3 0.3 0.0011 19.6 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PDZ_6 PF17820.1 RLN71236.1 - 2.4e-08 33.7 0.1 0.0012 18.6 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 RLN71236.1 - 5.9e-06 26.5 0.1 0.00035 20.9 0.0 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 RLN71236.1 - 0.03 14.7 0.0 2.7 8.4 0.0 2.5 2 0 0 2 2 2 0 PDZ domain Asp PF00026.23 RLN71239.1 - 1.6e-20 73.8 0.3 2.6e-20 73.1 0.3 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SOG2 PF10428.9 RLN71239.1 - 0.031 13.5 5.4 0.042 13.1 5.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TAXi_C PF14541.6 RLN71239.1 - 0.043 13.6 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal ASFV_J13L PF05568.11 RLN71239.1 - 0.39 10.4 0.0 0.39 10.4 0.0 2.4 3 0 0 3 3 3 0 African swine fever virus J13L protein Myb_DNA-binding PF00249.31 RLN71240.1 - 0.078 13.2 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain FYVE PF01363.21 RLN71241.1 - 3.5e-09 36.7 16.1 8.8e-09 35.4 16.1 1.7 1 0 0 1 1 1 1 FYVE zinc finger EMP24_GP25L PF01105.24 RLN71241.1 - 2.2 8.2 7.5 0.14 12.1 0.4 2.5 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD SlyX PF04102.12 RLN71241.1 - 3.2 8.4 14.1 9 7.0 10.8 3.5 2 0 0 2 2 2 0 SlyX PDZ PF00595.24 RLN71242.1 - 1.4e-17 63.8 0.0 0.005 17.2 0.0 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 RLN71242.1 - 6.2e-14 51.6 0.0 0.11 12.4 0.1 4.7 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 RLN71242.1 - 1e-08 35.3 0.1 0.58 10.5 0.0 4.4 4 0 0 4 4 4 3 PDZ domain Abhydrolase_1 PF00561.20 RLN71243.1 - 3e-10 40.2 0.1 0.00011 21.9 0.1 2.8 2 2 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 RLN71243.1 - 6e-05 23.1 0.0 0.001 19.1 0.0 2.3 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.8 RLN71243.1 - 0.00051 19.4 0.1 0.32 10.2 0.0 2.5 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN71243.1 - 0.34 11.5 6.9 23 5.5 6.9 2.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF908 PF06012.12 RLN71244.1 - 6.8 6.0 7.4 13 5.1 7.4 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) LRR_6 PF13516.6 RLN71255.1 - 0.00058 19.7 0.4 2.8 8.2 0.0 3.4 4 0 0 4 4 4 2 Leucine Rich repeat DASH_Dam1 PF08653.10 RLN71255.1 - 2.9 7.8 4.5 26 4.7 0.1 3.8 3 0 0 3 3 3 0 DASH complex subunit Dam1 Kelch_3 PF13415.6 RLN71256.1 - 4.1e-21 74.8 11.5 1.9e-07 31.2 0.1 6.4 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN71256.1 - 3e-17 62.2 0.1 1.2e-05 25.1 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 RLN71256.1 - 1.6e-14 53.6 7.5 0.00021 21.2 0.1 6.3 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 RLN71256.1 - 0.0012 18.3 0.1 5.3 6.7 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 RLN71256.1 - 0.0021 17.9 0.1 0.08 13.0 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Ephrin_rec_like PF07699.13 RLN71256.1 - 0.19 11.5 32.8 0.29 10.9 2.0 5.7 3 2 2 5 5 5 0 Putative ephrin-receptor like NCD3G PF07562.14 RLN71256.1 - 2.2 8.3 25.9 1.5 8.8 0.5 5.1 4 1 0 4 4 4 0 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 RLN71256.1 - 4.2 7.9 28.8 0.85 10.1 0.5 5.6 5 1 0 5 5 5 0 TNFR/NGFR cysteine-rich region ABC_tran_Xtn PF12848.7 RLN71257.1 - 1.9e-24 85.5 7.0 3.7e-24 84.5 7.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_tran PF00005.27 RLN71257.1 - 1.7e-22 80.4 0.2 1.5e-21 77.3 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 RLN71257.1 - 7.1e-08 32.6 5.8 1.1e-05 25.4 0.0 2.7 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RLN71257.1 - 3.5e-07 29.9 3.9 0.0054 16.2 0.0 3.4 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain MeaB PF03308.16 RLN71257.1 - 0.00069 18.7 0.9 0.004 16.2 0.1 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 RLN71257.1 - 0.002 18.2 0.4 0.0057 16.7 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 RLN71257.1 - 0.0026 17.5 0.2 0.0063 16.2 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 RLN71257.1 - 0.0034 17.1 0.1 0.017 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 RLN71257.1 - 0.0072 16.5 4.0 0.039 14.0 0.2 2.5 3 0 0 3 3 3 1 Helicase HerA, central domain EspB PF05802.11 RLN71257.1 - 0.0086 16.1 0.0 0.019 14.9 0.0 1.5 1 1 0 1 1 1 1 Enterobacterial EspB protein AAA_18 PF13238.6 RLN71257.1 - 0.015 15.8 0.2 0.76 10.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 RLN71257.1 - 0.026 14.8 0.3 0.34 11.2 0.3 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.23 RLN71257.1 - 0.038 14.0 0.5 0.38 10.8 0.0 2.2 2 0 0 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 RLN71257.1 - 0.042 13.8 0.9 0.085 12.8 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 RLN71257.1 - 0.042 14.3 3.9 0.29 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 RLN71257.1 - 0.056 13.6 0.3 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 RLN71257.1 - 0.11 12.2 1.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase Phage_int_SAM_2 PF12834.7 RLN71257.1 - 0.24 12.1 2.1 0.52 11.0 0.7 2.1 2 0 0 2 2 2 0 Phage integrase, N-terminal UvrD_C PF13361.6 RLN71257.1 - 0.95 8.8 5.2 1.5 8.1 5.2 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF4954 PF16314.5 RLN71258.1 - 1.6e-40 138.9 0.0 2e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) HTH_psq PF05225.16 RLN71258.1 - 6.9e-09 35.3 0.2 2.1e-08 33.8 0.2 1.8 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 RLN71258.1 - 0.0044 17.1 0.4 0.014 15.6 0.4 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 RLN71258.1 - 0.015 15.9 0.9 0.038 14.6 0.7 1.8 1 1 0 1 1 1 0 Homeodomain-like domain UPF0175 PF03683.13 RLN71258.1 - 0.17 11.6 0.1 0.38 10.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) BRO1 PF03097.18 RLN71260.1 - 1.4e-16 60.4 2.1 5e-15 55.2 0.7 2.1 2 0 0 2 2 2 2 BRO1-like domain Cutinase PF01083.22 RLN71261.1 - 4.9e-33 114.6 1.7 5.7e-33 114.4 1.7 1.0 1 0 0 1 1 1 1 Cutinase BLOC1_2 PF10046.9 RLN71268.1 - 0.0014 18.9 11.9 0.0016 18.7 8.2 2.4 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 POTRA_2 PF08479.11 RLN71268.1 - 0.034 14.0 2.7 0.15 11.9 0.1 2.6 2 0 0 2 2 2 0 POTRA domain, ShlB-type GAS PF13851.6 RLN71268.1 - 1.1 8.6 21.4 0.25 10.7 9.8 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.12 RLN71268.1 - 1.7 8.6 10.5 2.4 8.2 3.6 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 RLN71268.1 - 2.9 8.1 14.4 5.2 7.2 1.5 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family KLRAQ PF10205.9 RLN71268.1 - 4.6 7.5 17.1 0.18 12.0 9.0 2.7 2 2 0 2 2 2 0 Predicted coiled-coil domain-containing protein AATase PF07247.12 RLN71269.1 - 0.0017 17.0 0.0 0.0021 16.7 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Dak2 PF02734.17 RLN71269.1 - 0.11 12.4 0.0 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 DAK2 domain Pkinase PF00069.25 RLN71270.1 - 8.4e-66 222.0 0.0 1.3e-65 221.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN71270.1 - 4.2e-31 108.2 0.0 8.5e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 RLN71270.1 - 4.3e-09 36.8 0.1 1.2e-08 35.4 0.1 1.9 1 0 0 1 1 1 1 PH domain Kdo PF06293.14 RLN71270.1 - 0.00018 20.9 0.2 0.00036 19.9 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RLN71270.1 - 0.0073 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain C2 PF00168.30 RLN71270.1 - 0.017 15.4 0.0 0.06 13.6 0.0 2.0 1 0 0 1 1 1 0 C2 domain Multi_ubiq PF14452.6 RLN71270.1 - 0.024 14.9 0.0 0.08 13.2 0.0 1.9 1 0 0 1 1 1 0 Multiubiquitin Pkinase_fungal PF17667.1 RLN71270.1 - 0.031 13.1 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 RLN71270.1 - 0.042 13.8 0.2 0.15 11.9 0.3 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Sulfate_transp PF00916.20 RLN71271.1 - 4.9e-74 249.4 18.5 3e-37 128.3 0.6 2.3 2 0 0 2 2 2 2 Sulfate permease family STAS PF01740.21 RLN71271.1 - 2.8e-11 43.1 0.1 5.1e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 RLN71271.1 - 0.0056 17.0 0.1 0.016 15.5 0.1 1.8 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.20 RLN71272.1 - 2.5e-76 256.9 19.1 3.9e-40 137.8 0.8 2.5 3 0 0 3 3 3 2 Sulfate permease family STAS PF01740.21 RLN71272.1 - 6.5e-09 35.4 0.0 1.2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 RLN71272.1 - 0.0007 20.0 5.2 0.0007 20.0 5.2 3.4 2 1 1 3 3 3 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 RLN71272.1 - 0.058 13.7 0.2 0.16 12.3 0.2 1.7 1 0 0 1 1 1 0 STAS domain DUF3591 PF12157.8 RLN71276.1 - 8.8e-101 337.7 0.0 4.4e-63 213.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3591) Bromodomain PF00439.25 RLN71276.1 - 1.8e-18 66.4 0.0 3.2e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Bromodomain zf-CCHC_6 PF15288.6 RLN71276.1 - 0.00012 21.9 0.3 0.00032 20.5 0.3 1.7 1 0 0 1 1 1 1 Zinc knuckle 2OG-FeII_Oxy PF03171.20 RLN71277.1 - 8.3e-06 26.2 0.0 1.5e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4611 PF15387.6 RLN71277.1 - 0.11 12.7 1.9 0.21 11.8 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Lactamase_B_6 PF16661.5 RLN71278.1 - 2.8e-11 43.2 0.0 5.4e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain IQ PF00612.27 RLN71278.1 - 1e-08 34.2 17.7 0.056 13.2 1.6 4.6 4 0 0 4 4 4 4 IQ calmodulin-binding motif Beta_lactamase3 PF17030.5 RLN71278.1 - 0.0018 17.5 0.0 0.004 16.4 0.0 1.5 1 0 0 1 1 1 1 Putative beta-lactamase-like family Beta-Casp PF10996.8 RLN71278.1 - 0.0034 17.7 0.0 0.024 14.9 0.0 2.3 3 0 0 3 3 3 1 Beta-Casp domain UCH PF00443.29 RLN71279.1 - 5e-43 147.4 0.0 6.9e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 RLN71279.1 - 1.9e-17 62.8 2.7 3e-08 33.4 0.3 3.0 3 0 0 3 3 3 2 UBA/TS-N domain zf-UBP_var PF17807.1 RLN71279.1 - 3.8e-14 52.2 0.0 9.4e-14 50.9 0.0 1.7 1 0 0 1 1 1 1 Variant UBP zinc finger zf-UBP PF02148.19 RLN71279.1 - 8.7e-11 42.0 0.0 4.5e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 RLN71279.1 - 1e-09 38.5 0.3 9.6e-06 25.4 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF5536 PF17688.1 RLN71279.1 - 0.012 15.6 0.5 0.44 10.4 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5536) UBA_5 PF16577.5 RLN71279.1 - 0.012 15.7 0.0 3.3 7.9 0.0 2.6 2 0 0 2 2 2 0 UBA domain AAA_25 PF13481.6 RLN71280.1 - 0.034 13.7 0.2 0.14 11.7 0.0 2.1 3 0 0 3 3 3 0 AAA domain Y_phosphatase PF00102.27 RLN71280.1 - 0.064 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Chordopox_A20R PF05941.13 RLN71280.1 - 0.1 11.6 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus A20R protein Ras PF00071.22 RLN71280.1 - 0.16 11.6 0.1 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Ras family GBP PF02263.19 RLN71282.1 - 5.1e-13 48.9 1.0 5.8e-05 22.5 0.0 4.0 2 1 1 3 3 3 2 Guanylate-binding protein, N-terminal domain DUF4972 PF16342.5 RLN71282.1 - 3.2 7.5 10.8 1.6 8.4 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4972) MFS_1_like PF12832.7 RLN71283.1 - 3.5e-65 220.4 26.3 5.7e-65 219.7 26.3 1.3 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RLN71283.1 - 4.4e-22 78.5 36.5 6.2e-11 41.8 20.3 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 RLN71283.1 - 7.8e-16 58.1 23.5 1e-15 57.7 23.5 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter MFS_2 PF13347.6 RLN71283.1 - 9.7e-12 44.2 23.2 9.1e-09 34.4 8.8 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein LacY_symp PF01306.19 RLN71283.1 - 2e-09 36.7 25.5 4.3e-09 35.6 25.5 1.5 1 1 0 1 1 1 1 LacY proton/sugar symporter MFS_3 PF05977.13 RLN71283.1 - 6.8e-07 28.0 11.9 0.00053 18.5 5.6 2.1 1 1 1 2 2 2 2 Transmembrane secretion effector UNC-93 PF05978.16 RLN71283.1 - 0.0015 18.3 1.5 0.0015 18.3 1.5 2.8 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 PUCC PF03209.15 RLN71283.1 - 0.002 17.2 3.1 0.002 17.2 3.1 3.1 3 1 0 3 3 3 1 PUCC protein MFS_1_like PF12832.7 RLN71284.1 - 3.9e-63 213.6 26.2 7.1e-63 212.8 26.2 1.4 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RLN71284.1 - 2e-24 86.2 51.2 3.1e-19 69.1 27.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 RLN71284.1 - 4.2e-20 72.1 20.9 5.7e-20 71.7 20.9 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter MFS_2 PF13347.6 RLN71284.1 - 3.1e-12 45.8 19.4 1.2e-07 30.7 8.2 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein LacY_symp PF01306.19 RLN71284.1 - 5.2e-08 32.1 21.4 8.2e-08 31.4 21.4 1.3 1 0 0 1 1 1 1 LacY proton/sugar symporter FYVE PF01363.21 RLN71286.1 - 1.1e-13 51.1 13.4 2.6e-13 49.9 13.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN71286.1 - 0.00072 19.8 8.2 0.0014 18.8 8.2 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger INTAP PF16617.5 RLN71286.1 - 0.15 12.5 7.3 0.35 11.2 7.3 1.6 1 0 0 1 1 1 0 Intersectin and clathrin adaptor AP2 binding region Complex1_LYR PF05347.15 RLN71287.1 - 7.8e-07 29.1 0.0 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) EF-G-binding_N PF07299.11 RLN71287.1 - 0.043 14.3 0.6 0.2 12.2 0.1 1.9 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal Complex1_LYR_2 PF13233.6 RLN71287.1 - 0.063 14.0 0.1 0.099 13.4 0.1 1.4 1 1 0 1 1 1 0 Complex1_LYR-like Corazonin PF17308.2 RLN71287.1 - 0.13 12.7 0.0 0.39 11.1 0.1 1.7 1 1 1 2 2 2 0 Pro-corazonin HTH_Tnp_Tc5 PF03221.16 RLN71288.1 - 1e-05 25.4 0.0 2.8e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 RLN71288.1 - 0.052 13.3 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain SH3_3 PF08239.11 RLN71302.1 - 1.1e-05 25.6 0.6 1.2 9.5 0.0 4.2 4 0 0 4 4 4 3 Bacterial SH3 domain FYDLN_acid PF09538.10 RLN71302.1 - 8.1 7.2 12.7 13 6.5 2.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Coilin_N PF15862.5 RLN71302.1 - 8.8 6.1 9.2 7.6 6.3 3.5 2.7 2 0 0 2 2 2 0 Coilin N-terminus SWIM PF04434.17 RLN71303.1 - 1.3e-06 27.9 0.4 4.1e-06 26.4 0.4 1.9 1 0 0 1 1 1 1 SWIM zinc finger XPC-binding PF09280.11 RLN71303.1 - 0.067 12.9 0.8 5.9 6.7 0.1 2.6 2 0 0 2 2 2 0 XPC-binding domain Toxin_17 PF08086.11 RLN71303.1 - 0.15 12.4 2.7 0.32 11.3 2.7 1.5 1 0 0 1 1 1 0 Ergtoxin family GATase_5 PF13507.6 RLN71304.1 - 1.3e-99 332.6 0.1 1.7e-99 332.2 0.1 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 RLN71304.1 - 4.6e-15 56.1 0.1 8.4e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain Ipi1_N PF12333.8 RLN71305.1 - 0.019 15.6 0.1 7.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation PPR PF01535.20 RLN71306.1 - 3e-09 36.5 0.0 0.054 13.7 0.0 6.0 6 0 0 6 6 6 2 PPR repeat PPR_2 PF13041.6 RLN71306.1 - 3.1e-09 36.9 0.0 0.066 13.4 0.0 5.6 6 1 1 7 7 7 2 PPR repeat family PPR_3 PF13812.6 RLN71306.1 - 9.5e-07 28.8 0.0 0.92 9.6 0.0 5.6 5 1 2 7 7 7 2 Pentatricopeptide repeat domain PPR_long PF17177.4 RLN71306.1 - 2.7e-05 23.7 0.7 0.028 13.8 0.0 3.8 1 1 3 4 4 4 2 Pentacotripeptide-repeat region of PRORP TPR_12 PF13424.6 RLN71306.1 - 0.8 10.0 5.9 11 6.4 0.2 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat PPR_2 PF13041.6 RLN71307.1 - 2.5e-10 40.4 0.0 0.061 13.5 0.0 6.7 7 1 1 8 8 8 3 PPR repeat family PPR_long PF17177.4 RLN71307.1 - 1.3e-08 34.4 0.9 0.0062 15.9 0.0 3.5 1 1 2 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 RLN71307.1 - 9.3e-07 28.7 0.0 1.4 9.3 0.0 6.3 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.6 RLN71307.1 - 8.4e-05 22.6 0.0 14 5.8 0.0 5.4 3 1 2 6 6 6 1 Pentatricopeptide repeat domain adh_short PF00106.25 RLN71308.1 - 1.7e-14 53.7 0.0 8.2e-14 51.5 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN71308.1 - 5e-11 42.6 0.0 9.6e-10 38.4 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RimM PF01782.18 RLN71309.1 - 0.13 12.5 1.6 17 5.7 0.0 3.3 2 2 1 3 3 3 0 RimM N-terminal domain SR-25 PF10500.9 RLN71310.1 - 0.033 13.8 4.2 0.047 13.3 4.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 RLN71310.1 - 0.052 14.3 9.2 0.1 13.3 9.2 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein Metallophos PF00149.28 RLN71314.1 - 2.8e-34 119.4 1.1 4.5e-34 118.7 1.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 RLN71314.1 - 2e-26 92.1 0.0 4.3e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 RLN71314.1 - 1.5e-14 53.1 1.5 7.3e-05 22.4 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN71314.1 - 8.5e-13 47.4 2.1 0.0015 18.5 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN71314.1 - 1.5e-08 34.1 0.9 0.00017 21.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN71314.1 - 3e-06 26.8 2.7 0.0013 18.3 0.2 3.2 1 1 2 3 3 3 2 TPR repeat TPR_16 PF13432.6 RLN71314.1 - 4.6e-06 27.2 3.7 2e-05 25.1 0.6 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN71314.1 - 1.4e-05 25.2 0.4 5.1e-05 23.3 0.4 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN71314.1 - 0.0021 18.3 0.2 0.011 16.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN71314.1 - 0.0082 16.9 3.6 0.12 13.2 0.1 3.3 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN71314.1 - 0.015 15.3 0.1 6.5 7.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN71314.1 - 0.017 15.6 2.0 0.1 13.1 0.3 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN71314.1 - 0.029 14.7 2.6 0.51 10.7 0.3 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.17 RLN71314.1 - 0.041 14.3 1.6 0.085 13.3 1.6 1.5 1 0 0 1 1 1 0 Bacterial transcriptional activator domain Amidohydro_1 PF01979.20 RLN71315.1 - 5.4e-71 239.7 0.8 7.6e-71 239.2 0.8 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 RLN71315.1 - 1.4e-19 70.9 4.4 1.3e-17 64.4 0.2 2.3 2 0 0 2 2 2 2 Amidohydrolase family CobT PF06213.12 RLN71315.1 - 0.032 13.6 0.2 0.38 10.1 0.0 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT A_deaminase PF00962.22 RLN71315.1 - 0.032 13.5 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Adenosine/AMP deaminase PDEase_I_N PF08499.12 RLN71315.1 - 0.061 13.2 0.5 0.14 12.0 0.5 1.6 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal COG4 PF08318.12 RLN71316.1 - 6.6e-30 104.3 0.0 1.2e-29 103.5 0.0 1.5 1 0 0 1 1 1 1 COG4 transport protein Vps53_N PF04100.12 RLN71316.1 - 0.00033 19.8 0.6 0.0011 18.0 0.3 1.9 2 0 0 2 2 2 1 Vps53-like, N-terminal Sec15 PF04091.12 RLN71316.1 - 0.0047 16.4 0.0 0.08 12.3 0.0 2.8 3 0 0 3 3 3 1 Exocyst complex subunit Sec15-like SesA PF17107.5 RLN71316.1 - 0.028 14.6 3.4 13 6.0 0.0 4.2 3 1 2 5 5 5 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Rhodanese PF00581.20 RLN71317.1 - 9.5e-10 39.0 0.0 1.1e-09 38.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Phage_TAC_6 PF09550.10 RLN71317.1 - 0.03 14.8 0.5 4.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC PTPlike_phytase PF14566.6 RLN71317.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Peptidase_S41 PF03572.18 RLN71317.1 - 0.17 11.4 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S41 BRCT_2 PF16589.5 RLN71318.1 - 1e-21 77.1 0.0 0.00012 22.4 0.0 6.6 6 1 0 6 6 6 4 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 RLN71318.1 - 9.6e-20 70.8 0.0 0.0018 18.6 0.0 7.0 7 0 0 7 7 7 5 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 RLN71318.1 - 1.1e-18 66.9 1.0 1.8e-12 47.0 0.0 5.2 5 0 0 5 5 5 2 twin BRCT domain RTT107_BRCT_5 PF16770.5 RLN71318.1 - 2.1e-11 43.6 0.0 2.3e-07 30.6 0.0 4.0 4 0 0 4 4 4 2 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 RLN71318.1 - 5.8e-10 39.3 0.1 0.52 10.6 0.0 5.8 6 0 0 6 6 6 3 DNA ligase 3 BRCT domain Ham1p_like PF01725.16 RLN71319.1 - 1e-53 182.0 0.0 1.2e-53 181.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DUF5621 PF18532.1 RLN71319.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5621) Ephrin_rec_like PF07699.13 RLN71323.1 - 0.01 15.6 2.7 0.01 15.6 2.7 17.4 10 8 7 17 17 17 0 Putative ephrin-receptor like GTP_EFTU PF00009.27 RLN71324.1 - 6.5e-29 100.9 0.0 1.2e-28 100.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 RLN71324.1 - 2.5e-07 31.0 0.4 9.8e-07 29.1 0.4 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RLN71324.1 - 5.1e-07 29.8 0.0 9.7e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RLN71324.1 - 7.8e-05 22.6 0.2 0.001 19.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 RLN71324.1 - 0.00071 19.1 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ADIP PF11559.8 RLN71325.1 - 0.14 12.3 24.0 0.18 11.9 1.7 3.4 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 RLN71325.1 - 0.61 9.4 21.9 1.3 8.2 1.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 RLN71325.1 - 4.1 6.2 23.7 3 6.6 1.3 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein Spc24 PF08286.11 RLN71325.1 - 4.9 7.4 20.9 2.9 8.2 0.4 4.3 3 2 0 3 3 3 0 Spc24 subunit of Ndc80 BRE1 PF08647.11 RLN71325.1 - 4.9 7.3 21.1 1.1 9.4 2.0 3.7 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase HAUS-augmin3 PF14932.6 RLN71325.1 - 5.5 6.5 29.7 0.096 12.2 2.5 3.6 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 TPR_1 PF00515.28 RLN71326.1 - 2.4e-31 106.2 5.6 1e-06 28.3 0.0 6.2 5 2 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 RLN71326.1 - 1.7e-21 74.5 6.7 0.00011 22.0 0.6 6.1 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 RLN71326.1 - 8.6e-20 70.2 0.3 9.9e-08 31.6 0.1 5.5 5 1 1 6 6 6 3 TPR repeat TPR_8 PF13181.6 RLN71326.1 - 1.9e-17 62.0 4.4 6.7e-05 22.8 0.8 5.4 5 1 0 5 5 5 4 Tetratricopeptide repeat STI1 PF17830.1 RLN71326.1 - 4.9e-16 58.4 0.8 1.9e-15 56.5 0.6 2.1 2 0 0 2 2 2 1 STI1 domain TPR_17 PF13431.6 RLN71326.1 - 1.2e-12 47.3 1.8 0.0082 16.5 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 RLN71326.1 - 2e-09 37.6 0.4 0.0046 17.2 0.1 4.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN71326.1 - 2.3e-09 36.6 0.1 0.051 13.6 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN71326.1 - 2.6e-07 31.2 0.5 0.00086 19.9 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN71326.1 - 3.7e-06 27.3 0.0 1.6 9.8 0.0 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN71326.1 - 0.00022 21.7 0.9 2.1 9.1 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN71326.1 - 0.0005 20.5 0.7 0.3 11.6 0.0 4.3 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN71326.1 - 0.0016 18.2 0.4 4.1 7.4 0.1 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat RPN7 PF10602.9 RLN71326.1 - 0.0023 17.6 1.1 0.0046 16.7 0.3 1.9 1 1 0 1 1 1 1 26S proteasome subunit RPN7 TPR_9 PF13371.6 RLN71326.1 - 0.0074 16.4 0.0 0.1 12.8 0.0 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN71326.1 - 0.018 15.1 0.3 0.66 10.1 0.1 3.0 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat UDPGP PF01704.18 RLN71328.1 - 1.1e-21 77.0 0.0 1.5e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Anoctamin PF04547.12 RLN71329.1 - 5.4e-88 295.8 12.5 6.9e-88 295.4 12.5 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Palm_thioest PF02089.15 RLN71338.1 - 7e-47 160.3 0.0 8.3e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.18 RLN71338.1 - 0.00032 20.3 0.0 0.00066 19.2 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.20 RLN71338.1 - 0.00054 19.7 0.1 0.0014 18.3 0.0 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.14 RLN71338.1 - 0.00058 19.4 0.0 0.00092 18.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 RLN71338.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 RLN71338.1 - 0.099 11.9 0.1 0.32 10.2 0.1 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN71338.1 - 0.16 12.6 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family EF-hand_1 PF00036.32 RLN71352.1 - 2e-149 474.4 60.0 1.1e-05 24.6 0.0 26.7 27 0 0 27 27 27 24 EF hand EF-hand_7 PF13499.6 RLN71352.1 - 6.1e-131 427.1 57.1 2.5e-13 50.3 0.0 18.1 15 2 4 19 19 19 19 EF-hand domain pair EF-hand_6 PF13405.6 RLN71352.1 - 1.1e-129 411.5 61.1 0.0001 21.9 0.1 26.9 26 0 0 26 26 25 24 EF-hand domain EF-hand_5 PF13202.6 RLN71352.1 - 1.5e-109 353.1 73.5 4.9e-05 22.6 0.0 26.3 26 0 0 26 26 26 23 EF hand EF-hand_8 PF13833.6 RLN71352.1 - 9.7e-58 191.9 79.9 0.0044 16.9 0.1 26.1 20 5 6 26 26 25 19 EF-hand domain pair EF-hand_9 PF14658.6 RLN71352.1 - 2.2e-18 66.4 17.8 0.018 15.3 0.0 12.9 13 2 1 14 14 13 4 EF-hand domain EF-hand_2 PF09068.11 RLN71352.1 - 1.3e-17 64.1 0.0 0.024 14.8 0.0 10.8 10 3 0 10 10 10 3 EF hand EF-hand_4 PF12763.7 RLN71352.1 - 2e-14 53.4 48.6 0.75 9.8 0.0 20.5 10 8 12 23 23 23 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RLN71352.1 - 6e-12 45.9 16.2 1.9 8.9 0.1 15.3 16 4 1 17 17 17 1 Secreted protein acidic and rich in cysteine Ca binding region FANCM-MHF_bd PF16783.5 RLN71352.1 - 3.2e-07 30.4 4.6 13 5.9 0.0 8.1 9 0 0 9 9 8 0 FANCM to MHF binding domain Dockerin_1 PF00404.18 RLN71352.1 - 6.3e-07 29.5 17.1 27 5.1 0.0 12.7 13 4 2 15 15 13 0 Dockerin type I domain DUF1707 PF08044.11 RLN71352.1 - 2e-05 24.6 2.7 24 5.1 0.0 10.4 13 1 1 14 14 13 0 Domain of unknown function (DUF1707) EF-hand_10 PF14788.6 RLN71352.1 - 0.02 14.8 13.8 3.5 7.6 0.1 8.3 9 0 0 9 9 8 0 EF hand DUF4197 PF13852.6 RLN71352.1 - 0.02 14.6 0.1 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4197) eIF-5a PF01287.20 RLN71352.1 - 0.098 12.8 1.6 1.1 9.4 0.1 3.6 4 0 0 4 4 3 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold DUF3856 PF12968.7 RLN71352.1 - 0.11 12.6 4.5 31 4.6 0.0 4.8 4 0 0 4 4 4 0 Domain of Unknown Function (DUF3856) LXG PF04740.12 RLN71352.1 - 0.16 11.7 2.1 56 3.3 0.1 4.8 5 0 0 5 5 5 0 LXG domain of WXG superfamily EF-hand_14 PF17959.1 RLN71352.1 - 1.1 9.7 9.2 99 3.4 0.0 7.0 8 0 0 8 8 7 0 EF-hand domain HTH_48 PF17906.1 RLN71352.1 - 7.6 6.7 17.5 60 3.9 0.0 8.8 11 0 0 11 11 11 0 HTH domain in Mos1 transposase MFS_1 PF07690.16 RLN71358.1 - 1.6e-32 112.9 25.4 1.9e-32 112.5 25.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 RLN71358.1 - 1.9e-05 24.2 6.8 1.9e-05 24.2 6.8 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB PUF PF00806.19 RLN71358.1 - 0.043 13.5 0.1 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat TP_methylase PF00590.20 RLN71368.1 - 6.8e-49 166.7 0.4 1.2e-48 165.9 0.4 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Vault_2 PF17794.1 RLN71368.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Major Vault Protein repeat domain PI3_PI4_kinase PF00454.27 RLN71370.1 - 2.7e-51 174.8 0.0 5.1e-51 173.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 RLN71370.1 - 4e-47 160.0 2.6 7.5e-47 159.1 2.6 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 RLN71370.1 - 0.068 12.5 0.0 0.15 11.3 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) CRT-like PF08627.10 RLN71371.1 - 4.4e-10 39.0 0.7 4.4e-10 39.0 0.7 2.2 1 1 1 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Baculo_PEP_C PF04513.12 RLN71372.1 - 0.0074 16.3 12.1 2.9 8.0 0.0 3.4 3 1 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 RLN71372.1 - 0.0089 15.4 1.0 0.0089 15.4 1.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) DUF883 PF05957.13 RLN71372.1 - 0.027 15.1 3.1 0.027 15.1 3.1 4.8 2 2 3 5 5 5 0 Bacterial protein of unknown function (DUF883) Tup_N PF08581.10 RLN71372.1 - 0.32 11.3 25.3 0.21 11.9 3.4 5.1 4 2 1 5 5 5 0 Tup N-terminal HAP1_N PF04849.13 RLN71372.1 - 0.36 10.0 23.3 0.15 11.3 9.2 2.8 2 1 0 2 2 2 0 HAP1 N-terminal conserved region Allexi_40kDa PF05549.11 RLN71372.1 - 0.47 9.9 20.0 2.4 7.6 0.5 3.0 2 1 1 3 3 3 0 Allexivirus 40kDa protein DUF1664 PF07889.12 RLN71372.1 - 0.62 10.1 24.2 1 9.4 0.3 4.4 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) PIP5K PF01504.18 RLN71372.1 - 0.66 9.1 6.4 0.18 11.0 0.7 2.3 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase Jnk-SapK_ap_N PF09744.9 RLN71372.1 - 2.6 8.3 31.6 0.47 10.7 1.7 3.3 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 FlaC_arch PF05377.11 RLN71372.1 - 9.1 6.8 8.2 17 5.9 0.3 4.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) URO-D PF01208.17 RLN71373.1 - 5.1e-118 394.2 0.1 6.3e-107 357.7 0.0 2.0 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) DUF2009 PF09418.10 RLN71377.1 - 6.4e-201 668.3 0.0 7.5e-201 668.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 RLN71377.1 - 0.00033 20.7 5.5 0.00062 19.9 5.5 1.4 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 RLN71377.1 - 0.11 12.7 4.9 0.25 11.6 4.9 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Laminin_EGF PF00053.24 RLN71377.1 - 0.75 10.0 4.7 1.5 9.1 4.7 1.4 1 0 0 1 1 1 0 Laminin EGF domain Myb_DNA-binding PF00249.31 RLN71378.1 - 4.4e-07 30.0 0.1 9.3e-07 29.0 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain FAM199X PF15814.5 RLN71378.1 - 2 7.4 8.2 2.9 6.9 8.2 1.2 1 0 0 1 1 1 0 Protein family FAM199X SR-25 PF10500.9 RLN71378.1 - 2.3 7.7 7.7 3.6 7.1 7.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Laminin_G_3 PF13385.6 RLN71379.1 - 4.7e-13 49.6 0.0 1.2e-12 48.2 0.0 1.6 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF1080 PF06439.11 RLN71379.1 - 0.069 13.2 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) F-box_4 PF15966.5 RLN71379.1 - 0.099 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 F-box E1_dh PF00676.20 RLN71387.1 - 2e-54 184.6 0.0 2.8e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 RLN71387.1 - 1.4e-19 69.4 1.0 3e-19 68.3 1.0 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Transket_pyr PF02779.24 RLN71387.1 - 1.4e-10 41.1 0.0 2.4e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain R2K_2 PF18299.1 RLN71387.1 - 0.0005 20.0 0.1 0.0015 18.4 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain, R2K clade family 2 Cellulase PF00150.18 RLN71388.1 - 8.7e-26 91.0 6.0 1.1e-25 90.6 6.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 RLN71389.1 - 1.1e-21 77.5 1.9 1.4e-21 77.1 1.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2207 PF09972.9 RLN71390.1 - 1.3e-07 30.8 5.4 0.0018 17.1 0.6 3.2 3 0 0 3 3 3 3 Predicted membrane protein (DUF2207) Tweety PF04906.13 RLN71390.1 - 2e-06 26.8 10.5 0.0059 15.3 1.1 3.3 3 0 0 3 3 3 2 Tweety Prominin PF05478.11 RLN71390.1 - 2.6e-05 22.4 14.8 0.0001 20.5 0.2 3.6 3 1 1 4 4 4 2 Prominin Cyt_bd_oxida_I PF01654.17 RLN71390.1 - 0.002 16.8 0.6 0.072 11.7 0.1 2.4 2 0 0 2 2 2 1 Cytochrome bd terminal oxidase subunit I ETRAMP PF09716.10 RLN71390.1 - 0.0033 17.4 2.7 0.98 9.5 0.0 5.0 3 2 0 3 3 3 1 Malarial early transcribed membrane protein (ETRAMP) DUF1664 PF07889.12 RLN71390.1 - 0.013 15.5 3.3 4.9 7.2 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) LXG PF04740.12 RLN71390.1 - 0.13 12.0 2.8 0.22 11.2 1.4 2.0 2 0 0 2 2 2 0 LXG domain of WXG superfamily TMEM43 PF07787.12 RLN71390.1 - 0.17 11.2 3.8 0.17 11.3 0.8 2.3 2 0 0 2 2 2 0 Transmembrane protein 43 ApoLp-III PF07464.11 RLN71390.1 - 0.23 11.6 6.2 1.9 8.6 2.2 3.2 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) SUR7 PF06687.12 RLN71390.1 - 0.7 9.5 22.6 0.065 12.8 4.1 3.1 3 1 0 3 3 3 0 SUR7/PalI family Baculo_PEP_C PF04513.12 RLN71390.1 - 1.1 9.2 6.1 14 5.7 0.5 3.5 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cellulase PF00150.18 RLN71391.1 - 3.9e-24 85.6 5.9 5.6e-24 85.0 5.9 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) zf-CCHC PF00098.23 RLN71397.1 - 0.00025 21.0 1.6 0.00035 20.5 1.6 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 RLN71397.1 - 0.16 11.8 0.9 0.23 11.2 0.9 1.3 1 0 0 1 1 1 0 Zinc knuckle Arf PF00025.21 RLN71398.1 - 2.9e-42 144.1 0.0 4.7e-23 81.5 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 RLN71398.1 - 4.8e-06 26.1 0.2 0.066 12.6 0.1 2.0 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit cobW PF02492.19 RLN71398.1 - 0.0015 18.1 0.2 0.039 13.5 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.22 RLN71398.1 - 0.017 14.8 0.0 1.8 8.2 0.0 2.0 2 0 0 2 2 2 0 Ras family MeaB PF03308.16 RLN71398.1 - 0.019 14.0 0.0 0.034 13.1 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 RLN71398.1 - 0.031 14.5 0.0 0.32 11.2 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 RLN71398.1 - 0.034 13.5 0.0 0.049 13.0 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region 6PF2K PF01591.18 RLN71398.1 - 0.069 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase RsgA_GTPase PF03193.16 RLN71398.1 - 0.079 12.9 0.0 0.75 9.7 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 RLN71398.1 - 0.11 12.8 0.7 10 6.5 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain CAAD PF14159.6 RLN71398.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase G-alpha PF00503.20 RLN71398.1 - 0.15 11.2 0.1 0.36 10.0 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit Apyrase PF06079.11 RLN71399.1 - 2.7e-56 190.9 0.0 3e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Apyrase YhzD PF14120.6 RLN71399.1 - 0.069 13.3 0.2 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 YhzD-like protein ADH_zinc_N PF00107.26 RLN71413.1 - 1.2e-15 57.6 0.0 1.7e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN71413.1 - 0.00019 22.5 0.0 0.00026 22.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN71413.1 - 0.0002 20.8 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN71413.1 - 0.032 13.5 0.0 0.044 13.1 0.0 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 RLN71413.1 - 0.25 10.7 0.9 0.74 9.1 0.6 1.7 2 0 0 2 2 2 0 ThiF family Ammonium_transp PF00909.21 RLN71414.1 - 1.3e-116 389.6 32.5 1.6e-116 389.3 32.5 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family UL73_N PF12522.8 RLN71414.1 - 0.47 10.2 3.9 1.1 9.1 3.9 1.6 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal Glyco_hydro_1 PF00232.18 RLN71415.1 - 2.4e-50 171.3 0.1 2.8e-50 171.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 ADH_zinc_N_2 PF13602.6 RLN71416.1 - 5.2e-10 40.5 0.0 5.8e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MCM PF00493.23 RLN71427.1 - 5.5e-102 339.6 0.1 9e-102 338.9 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RLN71427.1 - 1.8e-31 108.6 0.4 3.8e-31 107.5 0.2 1.6 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 RLN71427.1 - 2e-19 69.8 0.2 7.2e-19 68.0 0.2 2.0 1 1 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 RLN71427.1 - 3.5e-14 53.3 0.0 7.7e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 RLN71427.1 - 3e-07 30.0 0.3 0.00016 21.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RLN71427.1 - 1.7e-05 24.7 0.0 4.4e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RLN71427.1 - 1.8e-05 24.8 0.1 0.00015 21.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 RLN71427.1 - 0.014 15.2 0.1 0.052 13.4 0.1 1.9 1 0 0 1 1 1 0 AAA lid domain AAA_16 PF13191.6 RLN71427.1 - 0.025 15.0 0.9 0.081 13.3 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 RLN71427.1 - 0.064 13.7 0.3 0.51 10.8 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 RLN71427.1 - 0.066 13.8 0.3 0.3 11.7 0.3 2.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal Chorion_3 PF05387.11 RLN71427.1 - 1.9 8.1 4.7 1.2 8.8 2.2 1.8 2 0 0 2 2 2 0 Chorion family 3 TP_methylase PF00590.20 RLN71428.1 - 5.1e-22 78.9 0.0 6.1e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Peptidase_S8 PF00082.22 RLN71429.1 - 9e-30 103.9 7.8 1.4e-29 103.3 7.8 1.3 1 0 0 1 1 1 1 Subtilase family Baculo_PEP_C PF04513.12 RLN71429.1 - 3.7 7.6 10.7 0.68 10.0 6.7 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_S8 PF00082.22 RLN71430.1 - 4.3e-29 101.7 9.6 6.8e-29 101.1 9.6 1.3 1 0 0 1 1 1 1 Subtilase family PTR2 PF00854.21 RLN71431.1 - 2.5e-59 201.1 7.7 7.3e-59 199.6 7.7 1.7 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 RLN71431.1 - 4.3e-10 39.1 30.4 4.4e-08 32.4 11.9 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5373 PF17343.2 RLN71431.1 - 0.087 12.7 1.8 0.15 11.9 0.3 2.2 1 1 0 1 1 1 0 Family of unknown function (DUF5373) CcmD PF04995.14 RLN71431.1 - 6.8 6.9 7.0 2.4 8.3 0.7 2.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Chordopox_A13L PF05961.11 RLN71431.1 - 7.1 7.0 6.9 0.39 11.0 0.2 2.3 2 0 0 2 2 2 0 Chordopoxvirus A13L protein PTR2 PF00854.21 RLN71432.1 - 5.5e-60 203.3 7.3 1.5e-59 201.8 7.3 1.7 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 RLN71432.1 - 1.7e-12 46.9 31.1 8.3e-08 31.5 11.4 3.5 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF5373 PF17343.2 RLN71432.1 - 0.024 14.5 0.4 0.024 14.5 0.4 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5373) Chordopox_A13L PF05961.11 RLN71432.1 - 0.095 13.0 0.3 0.68 10.2 0.1 2.5 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Phytochelatin PF05023.14 RLN71434.1 - 5.6e-86 287.2 0.0 7.1e-86 286.8 0.0 1.1 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.6 RLN71434.1 - 0.091 13.3 0.0 1.2 9.7 0.0 2.2 2 0 0 2 2 2 0 Peptidase_C39 like family DUF645 PF04875.12 RLN71438.1 - 0.0097 15.9 3.6 0.0097 15.9 3.6 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF645 ADK PF00406.22 RLN71439.1 - 1.6e-40 138.6 0.0 4.8e-40 137.1 0.0 1.8 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 RLN71439.1 - 2e-17 63.9 0.0 2e-17 63.9 0.0 3.8 2 2 2 4 4 4 1 AAA domain AAA_18 PF13238.6 RLN71439.1 - 6.4e-06 26.7 0.2 4e-05 24.2 0.0 2.5 2 2 0 2 2 2 1 AAA domain ADK_lid PF05191.14 RLN71439.1 - 0.00063 19.7 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 RLN71439.1 - 0.012 15.7 8.5 0.017 15.3 0.0 3.3 3 1 0 3 3 3 0 AAA domain PWI PF01480.17 RLN71439.1 - 0.05 13.9 0.0 0.97 9.8 0.0 2.7 2 1 0 2 2 2 0 PWI domain MCU PF04678.13 RLN71439.1 - 0.23 11.5 12.4 0.57 10.3 2.1 2.4 2 0 0 2 2 2 0 Mitochondrial calcium uniporter PAP2 PF01569.21 RLN71446.1 - 1.4e-10 41.1 0.8 1.7e-10 40.8 0.0 1.5 2 0 0 2 2 2 1 PAP2 superfamily DUF872 PF05915.12 RLN71446.1 - 0.031 14.4 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) PAP2 PF01569.21 RLN71447.1 - 4.9e-22 78.2 6.6 1e-10 41.5 0.0 3.5 3 1 0 3 3 3 2 PAP2 superfamily PAP2_3 PF14378.6 RLN71447.1 - 0.013 15.2 0.1 1.2 8.8 0.0 2.7 2 1 0 2 2 2 0 PAP2 superfamily NAD_binding_1 PF00175.21 RLN71448.1 - 1.4e-29 103.0 0.0 3.8e-29 101.5 0.0 1.7 2 1 1 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 RLN71448.1 - 1.7e-26 92.4 0.0 3.1e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 RLN71448.1 - 1.4e-05 25.3 0.0 0.0004 20.5 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain ERCC4 PF02732.15 RLN71449.1 - 3.1e-19 69.7 0.0 7.1e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain PAP2 PF01569.21 RLN71449.1 - 3.2e-07 30.2 1.5 5.8e-07 29.4 1.5 1.4 1 0 0 1 1 1 1 PAP2 superfamily HDA2-3 PF11496.8 RLN71449.1 - 0.087 12.0 0.2 0.48 9.5 0.1 2.0 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 UPF0254 PF06787.11 RLN71449.1 - 0.18 11.5 0.1 2.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0254) DTW PF03942.15 RLN71450.1 - 3.5e-11 43.2 0.0 8.2e-11 42.0 0.0 1.6 1 1 0 1 1 1 1 DTW domain zf-CCHC PF00098.23 RLN71450.1 - 3.8e-05 23.6 14.9 8.5e-05 22.5 2.3 3.2 4 0 0 4 4 4 2 Zinc knuckle zf-C2H2_10 PF16588.5 RLN71450.1 - 0.0068 16.1 1.1 0.017 14.8 1.1 1.6 1 0 0 1 1 1 1 C2H2 zinc-finger eIF3g PF12353.8 RLN71450.1 - 0.026 14.9 12.5 0.054 13.9 1.7 2.7 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_2 PF13696.6 RLN71450.1 - 0.068 13.0 1.4 0.068 13.0 1.4 2.9 3 0 0 3 3 3 0 Zinc knuckle HEAT PF02985.22 RLN71451.1 - 2.2e-05 24.3 8.0 0.82 10.1 0.0 6.9 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 RLN71451.1 - 7.1e-05 23.1 4.1 0.037 14.4 0.2 4.9 5 1 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 RLN71451.1 - 0.012 16.1 1.8 2.1 9.0 0.1 4.5 6 0 0 6 6 6 0 HEAT-like repeat Adaptin_N PF01602.20 RLN71451.1 - 0.27 9.8 4.4 8.3 4.8 0.1 3.8 3 2 1 4 4 4 0 Adaptin N terminal region Zot PF05707.12 RLN71452.1 - 7.2e-17 61.7 0.0 6.8e-16 58.5 0.0 2.0 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) Pho88 PF10032.9 RLN71486.1 - 2.6e-34 118.1 0.0 2.8e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) zf-C3HC4_2 PF13923.6 RLN71487.1 - 2.1e-11 43.5 8.9 4.4e-11 42.4 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN71487.1 - 1.8e-09 37.3 9.4 3.5e-09 36.4 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN71487.1 - 1.1e-07 32.1 8.8 2.3e-07 31.1 8.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RLN71487.1 - 1.2e-06 28.2 8.8 2.1e-06 27.5 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN71487.1 - 5.2e-06 26.3 8.5 1e-05 25.4 8.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RLN71487.1 - 3.9e-05 23.6 8.2 8.5e-05 22.5 8.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 RLN71487.1 - 0.00071 19.7 8.4 0.0014 18.8 8.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 RLN71487.1 - 0.0012 19.1 7.2 0.0035 17.6 7.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 RLN71487.1 - 0.0038 17.0 4.1 0.008 16.0 4.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 RLN71487.1 - 0.0048 16.7 3.6 0.0099 15.7 3.6 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 RLN71487.1 - 0.0062 16.3 6.8 0.018 14.8 6.8 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 RLN71487.1 - 0.061 13.4 3.0 0.12 12.4 3.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 RLN71487.1 - 1.8 8.4 7.1 0.8 9.5 4.2 2.0 1 1 0 1 1 1 0 RING-like zinc finger Arm PF00514.23 RLN71488.1 - 6.5e-51 168.9 15.1 1.5e-07 31.2 0.1 9.8 9 1 1 10 10 10 9 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN71488.1 - 5.3e-21 72.9 8.1 0.43 11.0 0.0 9.2 9 0 0 9 9 9 5 HEAT repeat HEAT_EZ PF13513.6 RLN71488.1 - 2.8e-19 69.2 26.4 2.6e-05 24.6 0.7 7.0 3 3 6 9 9 9 7 HEAT-like repeat HEAT_2 PF13646.6 RLN71488.1 - 5.2e-12 46.0 35.1 0.00075 19.8 3.5 5.0 1 1 5 6 6 6 6 HEAT repeats NFACT-R_2 PF18297.1 RLN71488.1 - 1e-05 25.7 1.9 25 5.1 0.0 5.6 2 2 4 6 6 6 0 NFACT protein RNA binding domain HEAT_PBS PF03130.16 RLN71488.1 - 4.9e-05 23.6 42.3 5 8.1 0.3 9.6 9 0 0 9 9 9 1 PBS lyase HEAT-like repeat T3SS_ExsE PF18286.1 RLN71488.1 - 0.0008 19.3 15.5 70 3.5 0.0 8.4 9 0 0 9 9 9 0 Type III secretion system ExsE Atx10homo_assoc PF09759.9 RLN71488.1 - 0.001 19.0 0.0 8.1 6.5 0.0 4.4 2 2 2 5 5 5 1 Spinocerebellar ataxia type 10 protein domain PfaD_N PF18328.1 RLN71488.1 - 0.0011 18.8 7.3 1.7e+02 2.3 0.0 7.5 8 0 0 8 8 8 0 Fatty acid synthase subunit PfaD N-terminal domain DUF294_C PF10335.9 RLN71488.1 - 0.0047 16.7 9.6 22 4.8 0.1 7.1 1 1 8 9 9 9 0 Putative nucleotidyltransferase substrate binding domain SelB-wing_1 PF09105.10 RLN71488.1 - 0.13 12.2 5.5 8.1 6.5 0.1 4.3 5 0 0 5 5 5 0 Elongation factor SelB, winged helix Antimicrobial17 PF08129.11 RLN71488.1 - 1.1 9.3 21.2 96 3.1 0.1 7.9 9 0 0 9 9 9 0 Alpha/beta enterocin family Tex_N PF09371.10 RLN71488.1 - 2.4 7.8 8.7 1.4e+02 2.1 0.0 5.4 2 2 5 7 7 7 0 Tex-like protein N-terminal domain GH97_C PF14509.6 RLN71488.1 - 4.4 7.6 5.9 3.1e+02 1.7 0.0 5.1 2 2 3 6 6 6 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation Pkinase_Tyr PF07714.17 RLN71489.1 - 7e-41 140.2 0.0 8.7e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN71489.1 - 1.8e-38 132.5 0.0 2.4e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 RLN71489.1 - 5e-05 22.2 0.0 8.6e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 RLN71489.1 - 0.0083 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 RLN71489.1 - 0.0099 15.8 0.4 0.015 15.2 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family TauD PF02668.16 RLN71490.1 - 2.1e-28 99.9 3.9 3.4e-18 66.4 0.1 2.0 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family ABC_membrane PF00664.23 RLN71491.1 - 1.3e-24 87.3 5.9 1.9e-24 86.8 5.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN71491.1 - 2.3e-17 63.8 0.0 5e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN71491.1 - 2e-05 24.1 0.0 3.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 RLN71491.1 - 0.005 15.7 0.3 0.0089 14.9 0.3 1.3 1 1 0 1 1 1 1 Predicted ATPase of the ABC class DUF3169 PF11368.8 RLN71491.1 - 0.057 12.9 0.0 0.057 12.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Glycophorin_A PF01102.18 RLN71491.1 - 0.062 13.5 0.0 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 Glycophorin A SbcCD_C PF13558.6 RLN71491.1 - 0.72 10.1 2.5 2.3 8.5 0.2 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 RLN71492.1 - 2.6e-17 63.6 0.0 4e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN71492.1 - 7.8e-07 28.8 0.1 9.6e-07 28.5 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 RLN71492.1 - 0.0025 18.0 1.1 0.065 13.5 1.1 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 RLN71492.1 - 0.0034 16.2 0.1 0.0039 16.1 0.1 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class CFIA_Pcf11 PF11526.8 RLN71493.1 - 0.0053 17.2 0.7 0.0053 17.2 0.7 2.8 2 0 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 Gon7 PF08738.10 RLN71493.1 - 0.019 15.0 1.8 0.087 12.9 1.8 2.1 1 1 0 1 1 1 0 Gon7 family EMP70 PF02990.16 RLN71494.1 - 1.5e-80 271.3 0.0 1.7e-80 271.2 0.0 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 TUDOR_5 PF18359.1 RLN71495.1 - 4.4e-11 42.3 1.8 3e-06 26.8 0.5 2.7 2 0 0 2 2 2 2 Histone methyltransferase Tudor domain 1 Tudor_3 PF18115.1 RLN71495.1 - 0.0015 18.3 0.1 0.017 15.0 0.0 2.4 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 RLN71495.1 - 0.056 13.9 0.1 20 5.7 0.0 3.1 2 0 0 2 2 2 0 Agenet domain Arm PF00514.23 RLN71495.1 - 0.16 12.0 17.2 2.8 8.1 0.1 6.2 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat rhaM PF05336.13 RLN71495.1 - 1.2 9.2 4.0 3.2 7.8 4.0 1.7 1 0 0 1 1 1 0 L-rhamnose mutarotase Pkinase_Tyr PF07714.17 RLN71496.1 - 3.6e-49 167.4 0.0 3.5e-44 151.0 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN71496.1 - 2.9e-43 148.1 0.0 7e-39 133.8 0.0 2.6 2 1 1 3 3 3 2 Protein kinase domain APH PF01636.23 RLN71496.1 - 0.0004 20.4 0.0 0.0004 20.4 0.0 2.5 3 1 0 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN71496.1 - 0.022 13.6 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 RLN71496.1 - 0.025 13.9 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 RLN71496.1 - 0.068 12.5 0.6 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RLN71496.1 - 0.098 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Tubulin_3 PF14881.6 RLN71497.1 - 8.5e-08 32.1 0.0 1.7e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Iso_dh PF00180.20 RLN71547.1 - 1.1e-22 80.6 0.0 1.8e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase FYVE PF01363.21 RLN71547.1 - 2.8e-07 30.5 3.6 5.6e-07 29.6 3.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-B_box PF00643.24 RLN71547.1 - 0.47 10.7 9.2 0.96 9.7 9.2 1.4 1 0 0 1 1 1 0 B-box zinc finger DUF382 PF04037.13 RLN71548.1 - 3e-57 192.3 0.3 3e-57 192.3 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 RLN71548.1 - 7.5e-21 73.7 4.9 9.4e-21 73.4 3.6 1.9 2 0 0 2 2 2 1 PSP N36 PF11438.8 RLN71548.1 - 0.19 11.6 2.2 0.63 9.9 2.2 2.0 1 0 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) PEX11 PF05648.14 RLN71549.1 - 3.6e-11 43.0 1.5 5.1e-06 26.1 0.3 2.1 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) CAF1 PF04857.20 RLN71550.1 - 6.8e-85 285.0 0.6 6.8e-85 285.0 0.6 1.7 2 0 0 2 2 2 1 CAF1 family ribonuclease DHHC PF01529.20 RLN71550.1 - 3.9e-21 75.6 2.6 1.1e-20 74.1 2.6 1.7 1 0 0 1 1 1 1 DHHC palmitoyltransferase Pox_A_type_inc PF04508.12 RLN71550.1 - 1.6 8.7 4.6 20 5.2 0.5 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat IGFBP PF00219.18 RLN71550.1 - 6.9 7.4 9.9 2.9 8.6 7.1 1.8 2 0 0 2 2 2 0 Insulin-like growth factor binding protein CSTF_C PF14304.6 RLN71551.1 - 6.6e-12 44.8 8.0 1.5e-11 43.6 8.0 1.7 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.6 RLN71551.1 - 1.5e-11 44.6 3.9 1.6e-11 44.5 0.2 2.2 2 1 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 Coiled-coil_56 PF09813.9 RLN71551.1 - 0.12 12.4 1.4 3.7 7.7 0.1 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 56 Ste5 PF11610.8 RLN71551.1 - 0.27 11.1 2.2 0.43 10.5 2.2 1.3 1 0 0 1 1 1 0 Scaffold protein Ste5, Fus3-binding region Sigma70_r4_2 PF08281.12 RLN71551.1 - 0.28 10.9 2.6 2.4 7.9 0.2 2.5 1 1 1 2 2 2 0 Sigma-70, region 4 WW PF00397.26 RLN71552.1 - 0.23 11.6 1.6 27 5.0 0.1 2.8 2 0 0 2 2 2 0 WW domain NPL PF17800.1 RLN71553.1 - 5.2e-07 30.2 0.1 5.2e-07 30.2 0.1 2.2 2 1 0 2 2 2 1 Nucleoplasmin-like domain Nucleoplasmin PF03066.15 RLN71553.1 - 0.016 15.7 0.1 0.084 13.4 0.1 2.2 1 1 0 1 1 1 0 Nucleoplasmin/nucleophosmin domain RR_TM4-6 PF06459.12 RLN71553.1 - 9.7 5.9 10.9 12 5.6 10.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Chorismate_bind PF00425.18 RLN71554.1 - 5.9e-87 291.5 0.0 8.9e-87 290.9 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 RLN71554.1 - 5.8e-13 49.3 0.0 1e-11 45.3 0.0 2.3 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region ABC2_membrane_3 PF12698.7 RLN71555.1 - 1.5e-38 132.8 16.8 2.2e-38 132.3 16.8 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 RLN71555.1 - 7.7e-27 94.5 0.0 1.4e-26 93.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN71555.1 - 8.5e-10 38.9 1.1 7.3e-08 32.6 0.0 2.8 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RLN71555.1 - 0.055 13.2 0.0 0.62 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Bac_rhamnosid6H PF17389.2 RLN71556.1 - 7.3e-11 41.9 0.1 2.9e-08 33.3 0.1 2.2 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain GDE_C PF06202.14 RLN71556.1 - 0.0057 15.6 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.18 RLN71556.1 - 0.047 12.5 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Trehalase Peptidase_M16_C PF05193.21 RLN71556.1 - 0.18 11.8 0.1 0.47 10.4 0.0 1.7 2 0 0 2 2 2 0 Peptidase M16 inactive domain LicD PF04991.13 RLN71557.1 - 0.00027 21.2 0.2 2.4 8.2 0.0 3.3 3 0 0 3 3 3 3 LicD family DUF1427 PF07235.11 RLN71557.1 - 0.0091 15.9 0.5 7 6.7 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1427) ABC_membrane PF00664.23 RLN71558.1 - 2.6e-48 165.0 18.8 3.5e-48 164.6 18.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN71558.1 - 1.3e-34 119.6 0.0 2.4e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN71558.1 - 0.0004 19.9 0.9 0.027 13.9 0.0 2.5 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RLN71558.1 - 0.003 17.8 0.2 0.024 14.9 0.2 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 RLN71558.1 - 0.0031 16.8 0.0 0.0059 15.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 RLN71558.1 - 0.0048 17.3 1.1 0.012 16.0 1.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 RLN71558.1 - 0.0062 16.3 0.1 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 RLN71558.1 - 0.012 15.4 0.7 0.69 9.7 0.1 2.3 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 RLN71558.1 - 0.014 14.2 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class APS_kinase PF01583.20 RLN71558.1 - 0.024 14.5 0.1 0.043 13.7 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase RsgA_GTPase PF03193.16 RLN71558.1 - 0.034 14.0 0.0 0.099 12.5 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase DEAD PF00270.29 RLN71558.1 - 0.045 13.5 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF87 PF01935.17 RLN71558.1 - 0.047 13.8 0.2 0.11 12.5 0.1 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 RLN71558.1 - 0.051 13.3 0.5 0.17 11.5 0.5 2.0 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 RLN71558.1 - 0.063 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 RLN71558.1 - 0.085 12.4 0.2 0.94 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 RLN71558.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit SbcCD_C PF13558.6 RLN71558.1 - 0.14 12.4 0.4 2 8.7 0.4 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Lzipper-MIP1 PF14389.6 RLN71559.1 - 0.094 13.0 1.2 0.52 10.6 0.6 2.4 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 CAAP1 PF15335.6 RLN71559.1 - 0.12 12.9 0.1 16 6.2 0.0 2.7 2 0 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 Med3 PF11593.8 RLN71559.1 - 4.6 6.3 5.9 9 5.4 5.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Methyltransf_11 PF08241.12 RLN71560.1 - 5.1e-37 126.4 0.1 2.1e-20 73.2 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 RLN71560.1 - 1.1e-36 125.5 0.2 8.2e-21 74.5 0.0 3.2 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 RLN71560.1 - 5.6e-30 104.2 0.0 1.6e-21 76.7 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 RLN71560.1 - 2.2e-29 102.4 0.0 1.4e-20 73.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 RLN71560.1 - 8.4e-23 81.0 0.1 2.7e-13 50.5 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain CMAS PF02353.20 RLN71560.1 - 2.3e-22 79.6 0.1 3.3e-19 69.2 0.1 2.3 2 1 0 2 2 2 2 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 RLN71560.1 - 1.9e-18 66.6 0.0 1e-12 47.9 0.1 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 RLN71560.1 - 4.8e-12 45.9 0.0 7.6e-09 35.4 0.0 2.4 2 0 0 2 2 2 2 AdoMet dependent proline di-methyltransferase PCMT PF01135.19 RLN71560.1 - 9.9e-11 41.8 0.0 2.6e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 RLN71560.1 - 2.8e-10 40.0 0.0 0.00023 20.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain CheR PF01739.18 RLN71560.1 - 1.6e-09 37.5 0.0 0.0037 16.8 0.0 3.3 2 1 1 3 3 3 2 CheR methyltransferase, SAM binding domain NodS PF05401.11 RLN71560.1 - 4.2e-08 33.0 0.0 7.1e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Nodulation protein S (NodS) TPMT PF05724.11 RLN71560.1 - 4.7e-08 33.0 0.0 7.2e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.11 RLN71560.1 - 8.2e-07 28.2 0.0 4.9e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) RrnaAD PF00398.20 RLN71560.1 - 2.6e-06 26.7 0.0 0.0029 16.7 0.0 2.4 2 0 0 2 2 2 2 Ribosomal RNA adenine dimethylase MetW PF07021.12 RLN71560.1 - 3.5e-06 26.8 0.0 6.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.14 RLN71560.1 - 6.1e-06 25.8 0.0 0.0088 15.5 0.0 2.3 2 0 0 2 2 2 2 Tellurite resistance protein TehB Bin3 PF06859.12 RLN71560.1 - 7.4e-05 23.4 0.1 0.081 13.6 0.0 2.9 2 1 0 2 2 2 1 Bicoid-interacting protein 3 (Bin3) FtsJ PF01728.19 RLN71560.1 - 0.00023 21.3 0.1 0.35 11.0 0.1 2.7 2 1 0 2 2 2 2 FtsJ-like methyltransferase PrmA PF06325.13 RLN71560.1 - 0.001 18.6 0.0 0.021 14.2 0.0 2.5 3 0 0 3 3 3 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 RLN71560.1 - 0.0013 18.8 0.0 0.0067 16.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_29 PF03141.16 RLN71560.1 - 0.0019 16.9 0.0 0.0068 15.0 0.0 1.9 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 RLN71560.1 - 0.0024 17.4 0.0 0.12 11.9 0.0 2.7 2 0 0 2 2 2 1 Putative methyltransferase DOT1 PF08123.13 RLN71560.1 - 0.0026 17.3 0.3 0.0077 15.8 0.2 1.9 1 1 0 1 1 1 1 Histone methylation protein DOT1 Met_10 PF02475.16 RLN71560.1 - 0.011 15.5 0.0 0.58 9.9 0.0 2.4 2 0 0 2 2 2 0 Met-10+ like-protein REJ PF02010.15 RLN71572.1 - 2.9e-68 230.7 10.8 1.6e-62 211.8 9.0 2.5 2 0 0 2 2 2 2 REJ domain EGF_2 PF07974.13 RLN71572.1 - 0.37 11.2 12.5 0.82 10.1 12.5 1.6 1 0 0 1 1 1 0 EGF-like domain Macoilin PF09726.9 RLN71572.1 - 1.4 7.4 7.5 2.1 6.8 7.5 1.2 1 0 0 1 1 1 0 Macoilin family PDZ_6 PF17820.1 RLN71573.1 - 3e-19 68.6 0.2 9.6e-05 22.2 0.0 6.0 6 0 0 6 6 6 4 PDZ domain Bromodomain PF00439.25 RLN71573.1 - 8.3e-16 57.8 0.1 1.7e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 Bromodomain PDZ PF00595.24 RLN71573.1 - 4.3e-11 43.0 0.6 0.064 13.6 0.0 6.3 5 1 1 6 6 6 3 PDZ domain FYRC PF05965.14 RLN71573.1 - 0.00014 21.9 0.0 0.00099 19.2 0.0 2.5 2 0 0 2 2 2 1 F/Y rich C-terminus DDT PF02791.17 RLN71573.1 - 0.00096 19.4 1.0 0.0032 17.8 1.0 2.0 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 RLN71573.1 - 0.0033 16.9 0.2 0.0092 15.5 0.2 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Mannosyl_trans3 PF11051.8 RLN71574.1 - 8.6e-07 28.6 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative PIGA PF08288.12 RLN71576.1 - 1.6e-36 124.8 0.1 3.5e-36 123.7 0.1 1.6 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 RLN71576.1 - 1.7e-27 96.5 0.5 2.9e-27 95.8 0.5 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 RLN71576.1 - 8.7e-27 93.7 0.0 1.4e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RLN71576.1 - 8.6e-24 84.5 0.2 1.5e-23 83.7 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 RLN71576.1 - 7.3e-13 49.3 0.7 7.3e-13 49.3 0.7 2.4 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 RLN71576.1 - 9.6e-06 25.9 0.0 1.7e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 ORC2 PF04084.14 RLN71576.1 - 0.23 10.3 0.0 0.43 9.4 0.0 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 2 DUF2298 PF10060.9 RLN71577.1 - 0.0054 15.5 1.2 0.0056 15.5 1.2 1.0 1 0 0 1 1 1 1 Uncharacterized membrane protein (DUF2298) PXB PF12828.7 RLN71578.1 - 0.003 17.6 0.2 0.013 15.5 0.1 2.0 2 0 0 2 2 2 1 PX-associated Laminin_II PF06009.12 RLN71579.1 - 2.2 8.3 11.9 0.91 9.5 1.3 3.3 3 0 0 3 3 3 0 Laminin Domain II BLOC1_2 PF10046.9 RLN71579.1 - 3.5 8.0 10.7 29 5.0 0.1 3.9 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sugar_tr PF00083.24 RLN71583.1 - 1.2e-69 235.4 6.6 1.3e-69 235.2 6.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN71583.1 - 8.2e-17 61.1 33.8 2.5e-11 43.1 15.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3792 PF12670.7 RLN71583.1 - 0.015 15.5 7.5 0.015 15.5 7.5 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3792) Abhydrolase_3 PF07859.13 RLN71584.1 - 2.2e-31 109.4 0.2 1e-30 107.2 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN71584.1 - 5.4e-13 48.6 0.0 8.2e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 RLN71584.1 - 0.01 15.3 0.2 0.039 13.4 0.2 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 RLN71584.1 - 0.012 14.9 0.0 0.047 13.0 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 COesterase PF00135.28 RLN71584.1 - 0.056 12.3 0.0 3.4 6.4 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family DUF4762 PF15959.5 RLN71584.1 - 0.082 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4762) Abhydrolase_3 PF07859.13 RLN71585.1 - 2.7e-34 118.9 1.3 1.8e-33 116.2 1.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN71585.1 - 1.9e-12 46.7 0.0 3.2e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 RLN71585.1 - 0.0046 16.5 0.1 0.02 14.4 0.1 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 RLN71585.1 - 0.063 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 OTU PF02338.19 RLN71586.1 - 1.8e-22 80.2 0.0 1.8e-16 60.8 0.0 2.3 2 0 0 2 2 2 2 OTU-like cysteine protease Peptidase_C65 PF10275.9 RLN71586.1 - 0.00019 20.9 0.1 0.055 12.9 0.0 2.4 1 1 1 2 2 2 2 Peptidase C65 Otubain DUF3246 PF11596.8 RLN71586.1 - 0.35 10.3 3.0 2.6 7.4 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Fcf2 PF08698.11 RLN71587.1 - 1.1e-32 112.3 1.2 2.4e-32 111.2 1.2 1.6 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing IFT46_B_C PF12317.8 RLN71588.1 - 1.8e-93 312.1 0.1 2.4e-93 311.7 0.1 1.2 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Peptidase_M8 PF01457.16 RLN71589.1 - 6e-65 219.9 14.8 1.6e-46 159.2 10.8 3.1 3 0 0 3 3 3 3 Leishmanolysin Zn_Tnp_IS1 PF03811.13 RLN71589.1 - 0.093 12.5 2.8 0.41 10.4 0.1 3.1 2 0 0 2 2 2 0 InsA N-terminal domain NTP_transferase PF00483.23 RLN71590.1 - 2.7e-44 151.6 0.0 6e-33 114.4 0.0 2.1 1 1 1 2 2 2 2 Nucleotidyl transferase Hexapep PF00132.24 RLN71590.1 - 1.5e-09 37.2 9.8 4.2e-07 29.4 2.7 3.6 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 RLN71590.1 - 0.00019 21.9 0.0 0.0007 20.0 0.0 1.9 1 1 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 RLN71590.1 - 0.00079 18.5 0.0 0.36 9.7 0.1 2.3 1 1 1 2 2 2 2 L-fucokinase Hexapep_2 PF14602.6 RLN71590.1 - 0.32 10.8 10.5 0.044 13.5 2.8 3.1 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase E1-E2_ATPase PF00122.20 RLN71591.1 - 1.8e-41 141.7 1.5 1.8e-41 141.7 1.5 3.2 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 RLN71591.1 - 4.1e-36 124.4 0.4 4.1e-36 124.4 0.4 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 RLN71591.1 - 5.4e-20 72.6 1.1 5.6e-16 59.5 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RLN71591.1 - 3.8e-17 61.7 0.0 9.9e-17 60.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 RLN71591.1 - 9.3e-17 60.9 0.0 5e-16 58.6 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 RLN71591.1 - 0.011 15.6 0.7 0.011 15.6 0.7 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 RLN71591.1 - 0.075 13.4 0.2 0.26 11.7 0.2 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hist_deacetyl PF00850.19 RLN71598.1 - 4.1e-77 259.7 0.0 5.4e-77 259.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain RYDR_ITPR PF01365.21 RLN71599.1 - 0.05 13.0 0.2 25 4.2 0.0 3.3 3 0 0 3 3 3 0 RIH domain SlyX PF04102.12 RLN71599.1 - 1 10.0 4.1 5.3 7.7 0.0 3.5 3 0 0 3 3 3 0 SlyX zf-RING_2 PF13639.6 RLN71603.1 - 8.3e-10 38.8 11.1 1.4e-09 38.2 11.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RLN71603.1 - 1.6e-07 31.5 8.5 2.9e-07 30.6 8.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 RLN71603.1 - 1.7e-06 27.7 8.1 3.3e-06 26.7 8.1 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 RLN71603.1 - 9.2e-06 25.6 3.7 1.8e-05 24.7 3.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 RLN71603.1 - 1.1e-05 25.2 10.6 1.8e-05 24.5 10.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN71603.1 - 0.0003 20.8 7.6 0.00061 19.8 7.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RLN71603.1 - 0.0016 18.3 12.7 0.0043 16.9 12.7 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN71603.1 - 0.023 14.5 7.8 0.048 13.5 7.8 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN71603.1 - 0.029 14.3 10.7 0.049 13.6 10.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Peptidase_S46 PF10459.9 RLN71603.1 - 0.062 11.9 0.1 0.074 11.7 0.1 1.0 1 0 0 1 1 1 0 Peptidase S46 Zn_ribbon_17 PF17120.5 RLN71603.1 - 0.063 12.9 7.4 0.11 12.1 7.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 RLN71603.1 - 0.12 12.3 8.9 0.2 11.6 8.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 RLN71603.1 - 0.53 10.4 7.7 1.2 9.4 7.7 1.6 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 RLN71603.1 - 2.6 8.3 10.7 7 6.9 10.7 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain IMS PF00817.20 RLN71604.1 - 3.4e-42 144.0 0.3 9.7e-42 142.5 0.1 2.0 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 RLN71604.1 - 6.5e-18 65.6 2.8 9.1e-18 65.1 1.3 2.1 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain zf-CpG_bind_C PF12269.8 RLN71604.1 - 0.00039 20.3 1.9 0.14 11.9 0.1 2.8 2 1 1 3 3 3 2 CpG binding protein zinc finger C terminal domain IMS_HHH PF11798.8 RLN71604.1 - 0.0059 16.9 0.1 0.015 15.6 0.1 1.7 1 0 0 1 1 1 1 IMS family HHH motif Lar_restr_allev PF14354.6 RLN71604.1 - 0.011 16.1 1.5 1.5 9.3 0.1 2.7 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-C2H2 PF00096.26 RLN71604.1 - 0.045 14.2 0.7 14 6.3 0.0 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-ribbon_3 PF13248.6 RLN71604.1 - 0.055 12.9 1.6 6.6 6.3 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 RLN71604.1 - 0.12 13.3 2.5 14 6.8 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RLN71604.1 - 0.17 11.9 0.5 34 4.6 0.0 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger cwf21 PF08312.12 RLN71604.1 - 0.18 12.0 2.2 1.4 9.1 0.0 2.9 3 0 0 3 3 3 0 cwf21 domain ABC_tran PF00005.27 RLN71605.1 - 4.2e-47 160.1 0.0 2.2e-23 83.3 0.0 3.8 3 2 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 RLN71605.1 - 9.8e-16 58.4 0.2 4.7e-05 23.3 0.0 4.0 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RLN71605.1 - 1.1e-12 47.8 0.1 0.0021 17.5 0.0 4.2 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RLN71605.1 - 2e-07 31.7 9.3 0.0031 18.1 0.0 4.1 4 1 0 4 4 4 2 AAA domain AAA_22 PF13401.6 RLN71605.1 - 1.1e-06 29.0 0.7 0.11 12.8 0.0 4.6 5 1 0 5 5 4 2 AAA domain AAA_28 PF13521.6 RLN71605.1 - 1.8e-06 28.3 0.0 0.095 12.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 RLN71605.1 - 2e-06 27.4 0.0 0.063 13.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 RLN71605.1 - 5.4e-06 26.8 0.2 0.18 12.2 0.0 3.8 4 0 0 4 4 3 2 RNA helicase Vac14_Fab1_bd PF12755.7 RLN71605.1 - 5.9e-06 26.8 0.1 0.056 14.1 0.0 3.0 3 0 0 3 3 2 2 Vacuolar 14 Fab1-binding region AAA PF00004.29 RLN71605.1 - 6.5e-06 26.6 0.0 0.017 15.5 0.0 3.5 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 RLN71605.1 - 1.1e-05 25.4 0.0 0.036 14.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 RLN71605.1 - 2e-05 25.0 0.3 0.79 10.1 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 RLN71605.1 - 2.3e-05 24.5 0.0 0.15 12.2 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 RLN71605.1 - 0.00011 22.7 6.5 0.65 10.6 0.0 4.5 5 0 0 5 5 3 2 AAA domain Chromo PF00385.24 RLN71605.1 - 0.00015 21.6 2.3 0.00015 21.6 2.3 2.1 2 0 0 2 2 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_33 PF13671.6 RLN71605.1 - 0.00018 21.7 0.0 1.5 9.0 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 RLN71605.1 - 0.0002 21.2 5.4 0.14 11.9 0.0 4.2 5 0 0 5 5 5 2 AAA ATPase domain Rad17 PF03215.15 RLN71605.1 - 0.00028 20.8 0.0 0.44 10.4 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_27 PF13514.6 RLN71605.1 - 0.00038 20.1 1.4 0.14 11.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 RLN71605.1 - 0.00051 20.0 0.0 0.063 13.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain G-alpha PF00503.20 RLN71605.1 - 0.00055 19.2 0.0 3 6.9 0.0 3.3 3 0 0 3 3 3 1 G-protein alpha subunit SbcCD_C PF13558.6 RLN71605.1 - 0.00099 19.3 0.1 0.25 11.6 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit CLASP_N PF12348.8 RLN71605.1 - 0.0029 17.2 0.2 0.021 14.4 0.0 2.3 1 1 0 2 2 2 1 CLASP N terminal AAA_24 PF13479.6 RLN71605.1 - 0.0034 17.1 0.0 0.75 9.5 0.0 3.1 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 RLN71605.1 - 0.0036 16.3 1.2 1.9 7.4 0.1 2.7 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 RLN71605.1 - 0.0038 17.0 0.1 3.5 7.3 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_7 PF12775.7 RLN71605.1 - 0.0071 15.9 0.0 4 6.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 RLN71605.1 - 0.009 16.1 1.5 1.2 9.2 0.1 3.9 4 0 0 4 4 4 1 Helicase HerA, central domain AAA_14 PF13173.6 RLN71605.1 - 0.0099 15.9 0.0 1.5 8.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain HEAT_2 PF13646.6 RLN71605.1 - 0.011 16.1 1.8 2.1 8.8 0.0 3.7 3 1 0 3 3 3 0 HEAT repeats Dynamin_N PF00350.23 RLN71605.1 - 0.017 15.2 0.7 1.2 9.2 0.0 3.5 4 0 0 4 4 3 0 Dynamin family Cytidylate_kin PF02224.18 RLN71605.1 - 0.021 14.6 0.5 5.1 6.8 0.0 3.1 3 0 0 3 3 3 0 Cytidylate kinase AAA_25 PF13481.6 RLN71605.1 - 0.039 13.5 0.0 8.7 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 RLN71605.1 - 0.04 13.1 0.0 1.1 8.4 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain HEAT PF02985.22 RLN71605.1 - 0.044 14.0 1.7 11 6.6 0.0 4.0 3 1 1 4 4 3 0 HEAT repeat ParcG PF10274.9 RLN71605.1 - 0.046 13.8 0.1 4.1 7.5 0.0 2.4 1 1 0 2 2 2 0 Parkin co-regulated protein DUF815 PF05673.13 RLN71605.1 - 0.049 12.8 0.0 9.5 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 RLN71605.1 - 0.081 12.3 0.4 17 4.7 0.0 2.8 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 RLN71605.1 - 0.085 12.8 0.6 30 4.5 0.1 3.5 4 0 0 4 4 3 0 NTPase PRK PF00485.18 RLN71605.1 - 0.095 12.4 0.0 6.9 6.4 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.14 RLN71605.1 - 0.1 12.6 0.8 14 5.7 0.0 3.6 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 RLN71605.1 - 0.12 12.0 0.0 3.5 7.2 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 RLN71605.1 - 0.13 12.3 0.0 29 4.7 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 RLN71605.1 - 0.13 12.1 0.0 0.13 12.1 0.0 4.0 5 0 0 5 5 4 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 RLN71605.1 - 0.14 11.8 0.0 13 5.4 0.0 2.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.17 RLN71605.1 - 1.9 8.2 4.3 13 5.4 0.2 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Aldo_ket_red PF00248.21 RLN71606.1 - 5.3e-69 232.6 0.0 6e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2334 PF10096.9 RLN71606.1 - 0.074 12.7 0.0 0.25 10.9 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Bac_DNA_binding PF00216.21 RLN71607.1 - 0.16 12.2 0.0 1 9.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial DNA-binding protein RCC1 PF00415.18 RLN71609.1 - 2.6e-35 120.8 7.7 6.7e-12 45.9 0.1 6.6 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN71609.1 - 1.3e-27 95.0 5.4 9.5e-10 38.0 0.1 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Kelch_5 PF13854.6 RLN71609.1 - 0.11 12.6 0.4 4.8 7.3 0.0 3.3 4 0 0 4 4 4 0 Kelch motif Aldo_ket_red PF00248.21 RLN71610.1 - 8e-65 218.9 0.0 9.1e-65 218.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 RLN71611.1 - 3.7e-68 229.9 0.0 4.2e-68 229.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Y_phosphatase2 PF03162.13 RLN71612.1 - 1.2e-43 148.5 0.0 1.6e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 RLN71612.1 - 0.0016 18.5 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 RLN71612.1 - 0.0024 17.5 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 RLN71612.1 - 0.027 14.3 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Strumpellin PF10266.9 RLN71613.1 - 1.8e-21 75.7 0.3 2.2e-21 75.4 0.3 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin Strumpellin PF10266.9 RLN71614.1 - 0 1337.1 0.1 0 1336.8 0.1 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin PhoU_div PF01865.16 RLN71614.1 - 0.084 12.2 1.8 0.28 10.5 1.3 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF47 ApoA-II PF04711.13 RLN71614.1 - 0.13 12.5 0.1 1.2 9.3 0.0 2.6 2 0 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) PTPA PF03095.15 RLN71615.1 - 6.9e-101 337.7 0.0 9.2e-99 330.7 0.0 2.0 1 1 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein SGTA_dimer PF16546.5 RLN71615.1 - 0.19 11.5 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Homodimerisation domain of SGTA BatA PF07584.11 RLN71616.1 - 0.028 14.8 0.7 0.037 14.4 0.7 1.1 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal PRCC PF10253.9 RLN71635.1 - 9.6 6.9 15.1 12 6.6 15.1 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SOG2 PF10428.9 RLN71638.1 - 9.5 5.3 23.7 13 4.9 23.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Mucin PF01456.17 RLN71639.1 - 0.12 12.3 31.2 0.18 11.8 31.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Med13_C PF06333.12 RLN71639.1 - 0.36 10.0 7.4 0.44 9.8 7.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Macoilin PF09726.9 RLN71639.1 - 0.43 9.1 1.9 0.53 8.8 1.9 1.1 1 0 0 1 1 1 0 Macoilin family Hamartin PF04388.12 RLN71639.1 - 0.85 8.2 6.2 0.88 8.2 6.2 1.0 1 0 0 1 1 1 0 Hamartin protein AKAP2_C PF15304.6 RLN71639.1 - 1.2 8.4 5.1 1.5 8.1 5.1 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus AAA_22 PF13401.6 RLN71644.1 - 0.014 15.7 0.1 0.38 11.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain Ribosomal_60s PF00428.19 RLN71644.1 - 0.025 15.1 0.3 0.025 15.1 0.3 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein AAA_33 PF13671.6 RLN71644.1 - 0.049 13.8 0.1 0.18 11.9 0.0 2.0 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 RLN71644.1 - 0.12 12.8 0.2 0.38 11.1 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain DUF4200 PF13863.6 RLN71646.1 - 5.2e-34 117.2 25.8 5.2e-34 117.2 25.8 4.5 2 2 1 4 4 4 2 Domain of unknown function (DUF4200) YvrJ PF12841.7 RLN71646.1 - 0.18 11.4 0.1 0.18 11.4 0.1 2.1 2 0 0 2 2 2 0 YvrJ protein family Bacillus_HBL PF05791.11 RLN71646.1 - 0.23 11.3 22.6 0.49 10.2 4.6 3.3 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Phage_int_SAM_4 PF13495.6 RLN71647.1 - 0.0039 17.6 0.2 0.0064 16.9 0.2 1.4 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain YL1 PF05764.13 RLN71650.1 - 0.014 15.6 5.1 0.015 15.4 5.1 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Rad9 PF04139.13 RLN71651.1 - 1e-35 123.4 1.1 1.4e-35 123.0 1.1 1.2 1 0 0 1 1 1 1 Rad9 E3_UFM1_ligase PF09743.9 RLN71652.1 - 1.7e-78 264.0 0.1 2.5e-78 263.4 0.1 1.3 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 MarR_2 PF12802.7 RLN71652.1 - 0.013 15.3 0.3 1.3 9.0 0.1 3.2 2 0 0 2 2 2 0 MarR family PMC2NT PF08066.12 RLN71652.1 - 0.11 13.2 3.6 1.6e+02 3.1 0.0 4.8 4 1 0 4 4 4 0 PMC2NT (NUC016) domain Sporozoite_P67 PF05642.11 RLN71652.1 - 7.1 4.6 12.4 0.31 9.1 4.9 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen PIP5K PF01504.18 RLN71659.1 - 1.2e-73 247.7 0.0 2.2e-73 246.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7TM_GPCR_Srsx PF10320.9 RLN71659.1 - 1.6e-06 27.7 1.1 3.7e-06 26.5 1.1 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_2 PF00002.24 RLN71659.1 - 0.0016 17.8 1.6 0.0016 17.8 1.6 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Ferric_reduct PF01794.19 RLN71659.1 - 0.11 12.6 1.8 0.26 11.4 1.8 1.6 1 0 0 1 1 1 0 Ferric reductase like transmembrane component UBM PF14377.6 RLN71659.1 - 0.14 11.6 0.1 0.55 9.8 0.1 1.9 2 0 0 2 2 2 0 Ubiquitin binding region Dicty_CAR PF05462.11 RLN71659.1 - 7.4 5.6 13.2 0.024 13.8 1.8 2.4 3 0 0 3 3 3 0 Slime mold cyclic AMP receptor Ldh_1_C PF02866.18 RLN71660.1 - 3.9e-29 101.7 0.1 5.1e-29 101.4 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 RLN71660.1 - 7e-24 84.5 0.1 1.4e-23 83.6 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_3_C PF01915.22 RLN71660.1 - 0.0011 18.9 0.4 0.1 12.6 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain CENP-B_dimeris PF09026.10 RLN71662.1 - 5.9 7.3 9.2 22 5.5 9.2 2.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Annexin PF00191.20 RLN71665.1 - 1.2e-07 31.7 0.1 4.5e-05 23.4 0.0 2.1 2 0 0 2 2 2 2 Annexin Annexin PF00191.20 RLN71666.1 - 3e-70 232.2 0.6 8.4e-12 45.0 0.0 6.5 7 0 0 7 7 7 6 Annexin AA_kinase PF00696.28 RLN71667.1 - 7.6e-36 123.9 1.8 1.6e-35 122.9 1.8 1.6 1 0 0 1 1 1 1 Amino acid kinase family Aldedh PF00171.22 RLN71667.1 - 1.6e-13 50.0 4.8 2.4e-09 36.2 2.0 2.6 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Pkinase PF00069.25 RLN71668.1 - 3.3e-57 193.8 0.1 7.3e-57 192.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN71668.1 - 3.6e-29 101.8 0.1 5e-29 101.4 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN71668.1 - 3.3e-06 26.6 0.0 5.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN71668.1 - 0.00099 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pro_isomerase PF00160.21 RLN71669.1 - 1.2e-16 61.4 0.0 2.2e-11 44.3 0.0 2.2 1 1 1 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF773 PF05600.12 RLN71671.1 - 1.8e-84 284.3 6.9 4.8e-41 141.1 0.0 3.0 2 1 1 3 3 3 3 CDK5 regulatory subunit-associated protein 3 ATG16 PF08614.11 RLN71671.1 - 0.063 13.5 6.6 0.56 10.4 0.2 3.1 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) DUF5082 PF16888.5 RLN71671.1 - 2.1 8.6 6.3 11 6.4 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) Annexin PF00191.20 RLN71672.1 - 1.5e-58 194.7 1.6 7.4e-15 54.8 0.0 4.2 4 0 0 4 4 4 4 Annexin Adeno_E3B PF03376.14 RLN71673.1 - 1.5 9.1 5.8 0.2 11.9 0.8 2.1 2 0 0 2 2 2 0 Adenovirus E3B protein RRM_1 PF00076.22 RLN71674.1 - 1.5e-77 255.4 3.1 1.8e-21 75.7 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RLN71674.1 - 3.3e-08 33.2 0.0 0.024 14.3 0.0 4.3 4 1 1 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RLN71674.1 - 2.1e-06 27.5 0.0 0.062 13.2 0.0 4.0 4 0 0 4 4 4 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 RLN71674.1 - 3.4e-06 27.0 0.1 0.36 10.9 0.0 4.7 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 RLN71674.1 - 0.0003 21.1 0.6 4.5 7.5 0.0 5.2 4 2 1 5 5 5 1 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 RLN71674.1 - 0.0096 16.0 0.0 13 6.0 0.0 3.9 4 0 0 4 4 4 1 RNA recognition motif RRM_3 PF08777.11 RLN71674.1 - 0.015 15.3 0.0 8 6.6 0.0 4.0 4 0 0 4 4 4 0 RNA binding motif RRM_Rrp7 PF17799.1 RLN71674.1 - 0.12 12.1 0.0 33 4.2 0.0 3.3 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain Dynactin_p22 PF07426.11 RLN71675.1 - 8.4e-19 68.0 0.6 3.6e-13 49.7 0.1 2.1 2 0 0 2 2 2 2 Dynactin subunit p22 HalX PF08663.10 RLN71675.1 - 0.008 16.5 0.3 0.008 16.5 0.3 2.7 2 1 0 2 2 2 1 HalX domain Cep57_MT_bd PF06657.13 RLN71675.1 - 0.025 15.0 3.8 0.28 11.6 0.0 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 NPV_P10 PF05531.12 RLN71675.1 - 0.067 13.7 1.1 0.56 10.7 0.0 2.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein SHE3 PF17078.5 RLN71675.1 - 0.099 12.4 1.6 0.14 11.8 1.0 1.5 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 ABC_tran_CTD PF16326.5 RLN71675.1 - 0.2 11.9 0.4 0.2 11.9 0.4 2.8 2 1 1 3 3 3 0 ABC transporter C-terminal domain GAS PF13851.6 RLN71675.1 - 0.41 10.0 8.4 0.77 9.1 6.4 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding PLDc_2 PF13091.6 RLN71676.1 - 5.5e-12 45.7 0.0 6.5e-10 39.0 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 RLN71676.1 - 8.9e-06 25.7 2.4 0.062 13.5 0.0 3.2 2 1 0 2 2 2 2 Phospholipase D Active site motif Gemini_V2 PF01524.17 RLN71676.1 - 0.067 13.4 0.1 9.5 6.5 0.0 2.7 3 0 0 3 3 3 0 Geminivirus V2 protein PLDc_2 PF13091.6 RLN71677.1 - 1.7e-12 47.3 0.0 4e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.22 RLN71677.1 - 0.0052 16.9 0.2 0.0052 16.9 0.2 2.0 2 0 0 2 2 2 1 Phospholipase D Active site motif EFhand_Ca_insen PF08726.10 RLN71677.1 - 0.024 14.7 0.8 0.047 13.8 0.1 1.9 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Terminase_3C PF17288.2 RLN71677.1 - 0.068 13.6 0.2 0.23 11.8 0.1 1.8 2 0 0 2 2 2 0 Terminase RNAseH like domain Peptidase_C48 PF02902.19 RLN71688.1 - 6.4e-12 45.8 0.1 1e-11 45.1 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain LupA PF18242.1 RLN71688.1 - 0.18 11.5 0.0 0.48 10.0 0.0 1.7 1 1 0 1 1 1 0 Legionella ubiquitin-specific protease A domain Aldo_ket_red PF00248.21 RLN71689.1 - 1.7e-68 231.0 0.0 1.9e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungus-induced PF10917.8 RLN71697.1 - 0.083 13.2 0.1 0.21 11.9 0.1 1.8 1 0 0 1 1 1 0 Fungus-induced protein Pex14_N PF04695.13 RLN71697.1 - 0.48 11.1 5.1 0.61 10.7 5.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SpoIIIAH PF12685.7 RLN71697.1 - 1.2 8.9 10.4 1.4 8.7 10.4 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Asp PF00026.23 RLN71707.1 - 3.5e-59 200.8 0.4 5.6e-59 200.1 0.4 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RLN71707.1 - 1.3e-15 58.1 0.3 5.4e-13 49.6 0.3 2.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 RLN71707.1 - 4.6e-05 24.0 0.3 0.0047 17.5 0.1 3.2 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 RLN71707.1 - 0.00028 21.4 0.0 0.0045 17.5 0.0 2.5 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 RLN71707.1 - 0.04 13.7 0.0 0.41 10.4 0.0 2.4 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal zf-RanBP PF00641.18 RLN71708.1 - 6.4e-05 22.2 4.2 0.00011 21.5 4.2 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 RLN71708.1 - 0.017 14.5 2.8 0.039 13.4 2.8 1.6 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain SUKH_5 PF14567.6 RLN71708.1 - 0.098 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall DcuC PF03606.15 RLN71708.1 - 0.17 10.3 0.0 0.23 9.9 0.0 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Pkinase PF00069.25 RLN71709.1 - 4.3e-08 32.9 0.0 9.1e-05 21.9 0.0 2.1 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN71709.1 - 6.7e-08 32.1 0.0 0.0013 18.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase DUF4448 PF14610.6 RLN71709.1 - 0.0013 18.5 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Adeno_E3_CR2 PF02439.15 RLN71709.1 - 0.0036 17.0 0.7 0.0073 16.0 0.7 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.10 RLN71709.1 - 0.037 13.4 0.7 0.072 12.5 0.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain QSOX_Trx1 PF18108.1 RLN71709.1 - 0.053 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 QSOX Trx-like domain Amnionless PF14828.6 RLN71709.1 - 0.26 10.0 0.0 0.37 9.6 0.0 1.2 1 0 0 1 1 1 0 Amnionless AMA-1 PF02430.15 RLN71709.1 - 0.28 10.1 0.0 0.39 9.6 0.0 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 Pkinase PF00069.25 RLN71710.1 - 1.1e-48 165.9 0.0 1.6e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN71710.1 - 2.7e-48 164.5 0.0 3.8e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 RLN71710.1 - 2e-08 34.4 11.1 0.0049 17.3 0.7 3.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN71710.1 - 4e-08 32.9 10.0 0.00012 21.8 0.4 3.8 1 1 3 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 RLN71710.1 - 0.00045 20.4 8.0 4.2 8.3 1.1 5.4 5 0 0 5 5 5 1 Leucine Rich Repeat DUF4448 PF14610.6 RLN71710.1 - 0.0015 18.4 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Adeno_E3_CR2 PF02439.15 RLN71710.1 - 0.031 14.1 0.7 0.057 13.2 0.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 LRR_6 PF13516.6 RLN71710.1 - 0.031 14.3 15.9 2.3 8.5 0.5 4.9 4 0 0 4 4 4 0 Leucine Rich repeat SKG6 PF08693.10 RLN71710.1 - 0.1 12.1 0.2 0.23 10.9 0.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain APH PF01636.23 RLN71710.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN71710.1 - 0.2 10.4 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase MHYT PF03707.16 RLN71711.1 - 0.0073 16.4 1.3 0.011 15.9 1.3 1.2 1 0 0 1 1 1 1 Bacterial signalling protein N terminal repeat GT87 PF09594.10 RLN71711.1 - 0.011 15.5 1.4 0.012 15.4 1.4 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 87 Herpes_gE PF02480.16 RLN71711.1 - 0.016 14.0 0.2 0.016 14.0 0.2 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF347 PF03988.12 RLN71711.1 - 0.018 15.2 1.9 0.018 15.2 1.9 1.8 2 1 0 2 2 2 0 Repeat of Unknown Function (DUF347) EphA2_TM PF14575.6 RLN71711.1 - 0.026 15.4 0.4 0.029 15.2 0.4 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 RLN71711.1 - 0.052 13.8 0.6 0.062 13.5 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Ly49 PF08391.10 RLN71711.1 - 0.073 13.4 0.3 0.079 13.3 0.3 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region BatD PF13584.6 RLN71711.1 - 0.15 10.9 0.0 0.15 10.9 0.0 1.0 1 0 0 1 1 1 0 Oxygen tolerance TMEM154 PF15102.6 RLN71711.1 - 0.25 11.2 0.0 0.26 11.2 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family Syndecan PF01034.20 RLN71711.1 - 4.1 7.4 5.0 5.9 6.9 5.0 1.2 1 0 0 1 1 1 0 Syndecan domain DUF3551 PF12071.8 RLN71712.1 - 0.068 13.2 0.2 0.09 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3551) TPPK_C PF12555.8 RLN71712.1 - 0.14 12.2 2.7 0.22 11.6 2.7 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal DUF4179 PF13786.6 RLN71712.1 - 0.22 12.0 1.1 0.28 11.7 1.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) KIAA1430 PF13879.6 RLN71713.1 - 0.23 12.3 2.1 0.49 11.2 2.1 1.6 1 0 0 1 1 1 0 KIAA1430 homologue DUF4407 PF14362.6 RLN71713.1 - 0.34 10.2 4.9 0.52 9.6 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4050 PF13259.6 RLN71713.1 - 7.4 6.8 7.2 17 5.7 7.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) ATG_C PF09333.11 RLN71724.1 - 2.5e-27 95.0 0.1 2.8e-27 94.9 0.1 1.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain CotH PF08757.11 RLN71725.1 - 1.4e-31 110.3 0.1 3.5e-31 108.9 0.1 1.6 2 0 0 2 2 2 1 CotH kinase protein PorA PF11271.8 RLN71725.1 - 0.16 11.2 3.2 1.1 8.5 3.5 1.9 2 0 0 2 2 2 0 Porin PorA zf-C2H2 PF00096.26 RLN71726.1 - 3.6e-05 24.0 13.8 0.25 11.9 0.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type F-box-like PF12937.7 RLN71726.1 - 4e-05 23.4 2.8 6.4e-05 22.8 0.8 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RLN71726.1 - 0.0021 17.9 1.1 0.0056 16.5 1.1 1.7 1 0 0 1 1 1 1 F-box domain FOXP-CC PF16159.5 RLN71726.1 - 0.5 11.0 5.5 5.8 7.6 2.1 3.5 2 1 1 3 3 3 0 FOXP coiled-coil domain Pkinase_Tyr PF07714.17 RLN71745.1 - 4.3e-14 52.4 0.0 5.1e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN71745.1 - 2.9e-13 49.8 0.0 3.1e-13 49.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Aldo_ket_red PF00248.21 RLN71746.1 - 2.9e-62 210.5 0.0 3.3e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sporozoite_P67 PF05642.11 RLN71748.1 - 1.2 7.2 14.2 1.7 6.6 14.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BK_channel_a PF03493.18 RLN71750.1 - 4.9e-16 58.7 0.0 1.2e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 RLN71750.1 - 4e-12 45.9 5.1 8.4e-12 44.9 5.1 1.6 1 0 0 1 1 1 1 Ion channel TrkA_N PF02254.18 RLN71750.1 - 4.9e-08 33.2 0.5 1.4e-05 25.3 0.1 2.4 2 0 0 2 2 2 2 TrkA-N domain Ion_trans PF00520.31 RLN71750.1 - 1e-05 24.9 2.1 1.7e-05 24.2 2.1 1.3 1 0 0 1 1 1 1 Ion transport protein Lig_chan PF00060.26 RLN71750.1 - 0.024 14.5 0.1 0.08 12.8 0.4 1.4 1 1 0 1 1 1 0 Ligand-gated ion channel Cupin_4 PF08007.12 RLN71751.1 - 1.8e-39 136.1 0.2 2.3e-39 135.8 0.2 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 RLN71751.1 - 6.1e-07 29.4 0.1 0.023 14.4 0.0 2.3 1 1 0 2 2 2 2 Cupin-like domain Cupin_2 PF07883.11 RLN71751.1 - 0.013 15.2 0.1 0.034 13.8 0.0 1.6 2 0 0 2 2 2 0 Cupin domain ARD PF03079.14 RLN71751.1 - 0.058 13.6 0.2 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 ARD/ARD' family zf-CXXC PF02008.20 RLN71753.1 - 1.3e-14 53.9 27.1 9.7e-12 44.7 18.2 2.3 2 0 0 2 2 2 2 CXXC zinc finger domain B_lectin PF01453.24 RLN71753.1 - 0.052 14.1 0.2 0.074 13.6 0.2 1.2 1 0 0 1 1 1 0 D-mannose binding lectin Fe-ADH PF00465.19 RLN71773.1 - 3.7e-38 131.3 4.0 4.3e-22 78.4 0.6 2.1 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 RLN71773.1 - 2.7e-05 24.0 0.9 0.00019 21.3 0.0 2.3 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase DUF4203 PF13886.6 RLN71774.1 - 3.3e-40 137.9 21.6 4.2e-40 137.6 21.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) CytB6-F_Fe-S PF08802.10 RLN71774.1 - 2.5 8.2 6.2 0.83 9.7 2.4 2.2 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit DUF4472 PF14739.6 RLN71775.1 - 9.1e-23 81.0 12.4 9.1e-23 81.0 12.4 7.3 4 1 3 8 8 8 1 Domain of unknown function (DUF4472) Kinesin PF00225.23 RLN71775.1 - 3.2e-18 65.8 0.0 9.6e-11 41.2 0.0 2.7 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 RLN71775.1 - 0.001 19.0 0.0 0.0041 17.1 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding HALZ PF02183.18 RLN71775.1 - 0.38 11.0 26.5 4.9 7.4 0.7 7.3 5 2 1 7 7 7 0 Homeobox associated leucine zipper HAD PF12710.7 RLN71776.1 - 6.5e-09 36.5 0.2 2.8e-08 34.4 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RLN71776.1 - 0.06 13.6 0.0 0.17 12.1 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Pec_lyase_C PF00544.19 RLN71777.1 - 3.1e-29 102.1 23.3 3.9e-15 56.0 8.5 4.0 2 2 0 2 2 2 2 Pectate lyase Beta_helix PF13229.6 RLN71777.1 - 1.1e-07 31.9 25.4 0.00097 19.0 7.0 4.1 2 2 1 3 3 3 3 Right handed beta helix region MMR_HSR1 PF01926.23 RLN71793.1 - 3.6e-06 27.1 0.0 6.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 RLN71793.1 - 7.9e-05 22.8 0.7 0.00044 20.3 0.7 2.1 1 1 0 1 1 1 1 Dynamin family IIGP PF05049.13 RLN71793.1 - 0.013 14.6 0.1 0.18 10.8 0.0 2.0 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 RLN71793.1 - 0.023 14.6 0.9 0.16 11.9 0.0 2.3 2 1 1 3 3 3 0 RsgA GTPase Roc PF08477.13 RLN71793.1 - 0.025 14.8 0.1 0.074 13.3 0.1 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 RLN71793.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.7 1 1 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.16 RLN71793.1 - 0.22 10.8 1.1 13 5.1 0.0 2.3 2 0 0 2 2 2 0 AIG1 family ADH_zinc_N PF00107.26 RLN71804.1 - 1.4e-16 60.7 0.5 2.8e-16 59.7 0.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN71804.1 - 3.9e-10 40.9 0.5 8.7e-10 39.8 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN71804.1 - 3.2e-06 27.0 0.0 1e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ThiF PF00899.21 RLN71804.1 - 0.074 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 ThiF family Bap31 PF05529.12 RLN71818.1 - 1.2e-13 51.1 1.0 2.8e-13 49.9 1.0 1.7 1 1 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 RLN71818.1 - 0.00096 19.1 25.1 0.11 12.5 3.6 4.5 2 2 1 3 3 3 2 Bap31/Bap29 cytoplasmic coiled-coil domain UPF0242 PF06785.11 RLN71818.1 - 0.0035 17.5 16.7 0.025 14.7 14.9 2.1 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Csm1_N PF18504.1 RLN71818.1 - 0.079 13.3 0.9 0.079 13.3 0.9 3.2 1 1 2 3 3 3 0 Csm1 N-terminal domain DivIC PF04977.15 RLN71818.1 - 0.22 11.3 20.8 0.065 13.0 4.1 3.3 3 0 0 3 3 3 0 Septum formation initiator DUF4600 PF15372.6 RLN71818.1 - 0.22 12.0 12.7 0.3 11.5 10.2 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4600) DUF3734 PF12536.8 RLN71818.1 - 0.44 10.9 3.1 0.44 10.9 1.7 1.8 1 1 0 1 1 1 0 Patatin phospholipase DUF2058 PF09831.9 RLN71818.1 - 0.45 10.7 16.9 0.029 14.5 11.4 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) YabA PF06156.13 RLN71818.1 - 1 10.1 12.7 0.24 12.1 0.8 3.0 1 1 2 3 3 3 0 Initiation control protein YabA DUF812 PF05667.11 RLN71818.1 - 1.1 8.1 18.2 1.4 7.7 18.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4559 PF15112.6 RLN71818.1 - 3.1 7.4 9.5 0.18 11.5 2.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) Occludin_ELL PF07303.13 RLN71818.1 - 5.6 7.8 9.5 8 7.3 3.9 2.3 1 1 1 2 2 2 0 Occludin homology domain FAD-SLDH PF12318.8 RLN71818.1 - 8.5 6.4 10.2 0.97 9.5 0.6 2.7 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Pox_L3_FP4 PF03339.14 RLN71819.1 - 7.7 5.4 7.6 0.4 9.6 0.8 2.1 1 1 0 2 2 2 0 Poxvirus L3/FP4 protein Acetyltransf_1 PF00583.25 RLN71823.1 - 6e-22 78.1 0.1 1.2e-11 44.9 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RLN71823.1 - 3.8e-16 59.2 0.0 7.9e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN71823.1 - 7.6e-16 58.3 0.0 2e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 RLN71823.1 - 2.6e-06 28.2 0.3 0.03 15.0 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN71823.1 - 1.2e-05 25.2 0.8 0.0062 16.5 0.2 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_6 PF13480.7 RLN71823.1 - 0.00032 20.9 0.6 1.1 9.4 0.0 3.3 3 1 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 RLN71823.1 - 0.037 14.2 0.0 16 5.7 0.0 2.6 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Transketolase_C PF02780.20 RLN71823.1 - 0.079 12.8 0.0 7.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Transketolase, C-terminal domain PanZ PF12568.8 RLN71823.1 - 0.11 12.2 0.3 17 5.2 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ VHL_C PF17211.3 RLN71823.1 - 0.18 11.8 0.1 7.9 6.6 0.0 2.6 2 0 0 2 2 2 0 VHL box domain Acetyltransf_1 PF00583.25 RLN71824.1 - 4.4e-13 49.5 0.1 5.7e-13 49.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RLN71824.1 - 5.1e-11 42.9 0.1 7.9e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RLN71824.1 - 1.8e-09 37.6 0.1 2.5e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN71824.1 - 2.6e-05 24.1 0.1 4.3e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 RLN71824.1 - 0.018 15.2 0.1 0.041 14.0 0.1 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 RLN71824.1 - 0.05 13.8 0.1 0.33 11.1 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF640 PF04852.12 RLN71824.1 - 0.18 12.0 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF640) Acetyltransf_4 PF13420.7 RLN71824.1 - 0.21 11.7 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 RLN71825.1 - 1.3e-43 149.3 0.0 1.8e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN71825.1 - 7.6e-33 113.9 0.0 1e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN71825.1 - 2.7e-05 23.1 0.0 0.00021 20.2 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 RLN71825.1 - 0.0024 17.2 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RLN71825.1 - 0.0029 16.6 0.0 0.0039 16.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RLN71825.1 - 0.006 16.5 0.1 0.01 15.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN71825.1 - 0.032 13.6 0.1 0.055 12.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 RLN71825.1 - 0.043 12.9 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 RLN71825.1 - 0.048 13.3 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 ParcG PF10274.9 RLN71826.1 - 9.8e-67 224.6 0.0 1.1e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein Pro-kuma_activ PF09286.11 RLN71827.1 - 9.4e-21 74.6 0.0 2.6e-20 73.2 0.0 1.8 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 RLN71827.1 - 4e-07 29.6 0.5 8.1e-07 28.6 0.5 1.5 1 0 0 1 1 1 1 Subtilase family Acetyltransf_1 PF00583.25 RLN71828.1 - 1.1e-61 206.3 2.0 5e-14 52.5 0.0 4.3 4 0 0 4 4 4 4 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RLN71828.1 - 1.2e-44 150.6 0.4 1.2e-09 38.5 0.0 4.3 4 0 0 4 4 4 4 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RLN71828.1 - 9.2e-37 125.8 0.6 3.6e-08 33.4 0.0 4.2 4 0 0 4 4 4 4 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 RLN71828.1 - 4.7e-24 85.6 4.4 4.2e-05 24.2 0.1 4.1 4 0 0 4 4 4 4 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN71828.1 - 8.1e-22 77.0 3.1 0.00017 21.5 0.1 4.4 4 0 0 4 4 4 4 FR47-like protein Acetyltransf_4 PF13420.7 RLN71828.1 - 1.2e-15 57.9 0.0 0.0061 16.7 0.0 4.6 4 1 0 4 4 4 3 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 RLN71828.1 - 1.4e-14 54.0 0.0 0.011 15.8 0.0 4.6 4 0 0 4 4 4 4 GCN5-related N-acetyl-transferase PanZ PF12568.8 RLN71828.1 - 7.3e-12 45.1 4.4 0.053 13.3 0.1 4.4 4 0 0 4 4 4 4 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_6 PF13480.7 RLN71828.1 - 5.1e-10 39.7 0.3 0.003 17.7 0.0 4.7 4 1 0 4 4 4 2 Acetyltransferase (GNAT) domain TcpQ PF10671.9 RLN71828.1 - 9.4e-08 32.1 6.4 1.2 9.3 0.1 4.5 4 0 0 4 4 4 3 Toxin co-regulated pilus biosynthesis protein Q Acetyltransf_9 PF13527.7 RLN71828.1 - 7.5e-06 26.0 7.9 1.9 8.6 0.0 6.8 7 1 0 7 7 7 2 Acetyltransferase (GNAT) domain AstA PF04958.12 RLN71828.1 - 5e-05 22.0 0.0 2.3 6.7 0.0 4.3 4 0 0 4 4 4 1 Arginine N-succinyltransferase beta subunit Acetyltransf_13 PF13880.6 RLN71828.1 - 0.00053 19.9 7.6 9.7 6.3 0.1 4.6 4 0 0 4 4 4 0 ESCO1/2 acetyl-transferase PKS_DE PF18369.1 RLN71828.1 - 0.0015 19.0 1.1 7.2 7.3 0.0 4.4 4 0 0 4 4 3 1 Polyketide synthase dimerisation element domain DUF2164 PF09932.9 RLN71828.1 - 0.004 17.2 0.3 13 5.9 0.0 3.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2164) DIL PF01843.19 RLN71828.1 - 0.0042 17.3 0.1 79 3.6 0.0 4.3 4 0 0 4 4 4 0 DIL domain DUF296 PF03479.15 RLN71828.1 - 0.0067 16.8 0.1 17 5.8 0.0 3.7 4 0 0 4 4 4 0 Plants and Prokaryotes Conserved (PCC) domain DAHP_snth_FXD PF18152.1 RLN71828.1 - 0.0083 15.9 0.1 12 5.9 0.0 3.4 3 0 0 3 3 3 0 DAHP synthase ferredoxin-like domain Gemin7 PF11095.8 RLN71828.1 - 0.2 11.6 0.0 35 4.4 0.0 2.7 2 0 0 2 2 2 0 Gem-associated protein 7 (Gemin7) Acetyltransf_1 PF00583.25 RLN71829.1 - 5.7e-14 52.3 0.0 7.4e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RLN71829.1 - 1.4e-10 41.4 0.0 2.1e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RLN71829.1 - 8.3e-10 38.7 0.0 1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 RLN71829.1 - 1e-06 29.5 0.1 1.2e-06 29.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN71829.1 - 4.6e-05 23.3 0.0 8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 RLN71829.1 - 0.00022 21.4 0.0 0.00034 20.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 RLN71829.1 - 0.025 14.7 0.2 0.69 10.0 0.2 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain T6SS-SciN PF12790.7 RLN71829.1 - 0.039 13.7 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 PanZ PF12568.8 RLN71829.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ BT1 PF03092.16 RLN71830.1 - 2.8e-09 35.8 0.9 2.8e-09 35.8 0.9 1.9 3 0 0 3 3 3 1 BT1 family Vma12 PF11712.8 RLN71830.1 - 2.6 8.1 6.7 0.27 11.3 1.3 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Sporozoite_P67 PF05642.11 RLN71843.1 - 0.27 9.3 0.0 0.39 8.8 0.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Peroxidase_2 PF01328.17 RLN71845.1 - 3.1e-48 164.8 0.0 3.9e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Rhodanese PF00581.20 RLN71846.1 - 0.0016 18.9 0.0 0.018 15.6 0.0 2.3 1 1 0 1 1 1 1 Rhodanese-like domain MCM_bind PF09739.9 RLN71846.1 - 0.63 8.4 2.7 1 7.7 2.7 1.4 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Peroxidase_2 PF01328.17 RLN71847.1 - 2.7e-48 165.0 0.0 3.3e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Peroxidase_2 PF01328.17 RLN71848.1 - 8.2e-48 163.4 0.0 1e-47 163.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 TrbC PF04956.13 RLN71850.1 - 0.043 14.0 1.3 0.048 13.9 1.3 1.1 1 0 0 1 1 1 0 TrbC/VIRB2 family BAG PF02179.16 RLN71853.1 - 0.0044 17.4 0.4 0.012 16.0 0.4 1.8 1 0 0 1 1 1 1 BAG domain DUF3418 PF11898.8 RLN71854.1 - 0.045 12.4 0.2 0.054 12.2 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) NAM-associated PF14303.6 RLN71854.1 - 0.15 12.7 0.0 0.31 11.8 0.0 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain PX PF00787.24 RLN71855.1 - 2.6e-10 40.3 0.0 3.5e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 PX domain DUF3275 PF11679.8 RLN71855.1 - 0.58 10.1 6.2 0.89 9.5 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) MafB19-deam PF14437.6 RLN71859.1 - 6.4e-07 29.2 0.0 1.4e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 RLN71859.1 - 8.9e-06 25.5 0.4 3.3e-05 23.7 0.0 2.2 3 1 0 3 3 3 1 Cytidine and deoxycytidylate deaminase zinc-binding region EF-hand_7 PF13499.6 RLN71860.1 - 1.1e-06 28.9 0.2 0.0014 19.0 0.0 1.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN71860.1 - 0.0021 17.9 0.0 0.0088 15.9 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 RLN71860.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 RLN71860.1 - 0.025 14.1 0.1 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 EF hand KIX_2 PF16987.5 RLN71861.1 - 1.3e-05 25.1 0.0 1.3e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 KIX domain KIX PF02172.16 RLN71861.1 - 0.00097 19.4 0.1 0.002 18.3 0.1 1.5 1 0 0 1 1 1 1 KIX domain TBP PF00352.21 RLN71862.1 - 7.1e-49 163.7 0.0 6.7e-28 96.5 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DEAD PF00270.29 RLN71863.1 - 8.8e-37 126.6 0.6 1.3e-36 126.0 0.6 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN71863.1 - 4.2e-28 97.9 0.1 4.2e-27 94.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN71863.1 - 2.6e-07 30.8 0.0 4.1e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 RLN71863.1 - 0.027 13.3 0.3 0.34 9.6 0.0 2.2 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 HEM4 PF02602.15 RLN71863.1 - 0.03 13.7 0.5 0.072 12.4 0.0 1.8 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD T4SS-DNA_transf PF02534.14 RLN71863.1 - 0.12 11.2 0.0 0.28 10.0 0.0 1.6 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Glyco_transf_7C PF02709.14 RLN71864.1 - 2.2e-23 81.7 0.2 4.9e-23 80.6 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 RLN71864.1 - 2.7e-11 43.2 0.0 5.4e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.9 RLN71864.1 - 0.0022 17.5 0.1 0.012 15.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 CHGN PF05679.16 RLN71864.1 - 0.013 14.4 0.0 0.034 13.0 0.0 1.6 2 0 0 2 2 2 0 Chondroitin N-acetylgalactosaminyltransferase HEAT_2 PF13646.6 RLN71865.1 - 7e-05 23.1 10.8 0.29 11.5 0.5 4.7 3 2 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 RLN71865.1 - 0.00023 21.3 1.1 4.6 7.3 0.0 4.2 2 2 0 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RLN71865.1 - 0.42 11.0 19.1 1.3 9.5 0.1 6.3 6 0 0 6 6 6 0 HEAT repeat HEAT_EZ PF13513.6 RLN71865.1 - 0.77 10.3 13.8 11 6.7 0.0 5.7 5 2 0 5 5 5 0 HEAT-like repeat Arm PF00514.23 RLN71865.1 - 2.5 8.3 7.1 15 5.8 0.0 5.2 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Fibrillarin PF01269.17 RLN71866.1 - 3e-28 98.5 0.0 3.3e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin LRR_8 PF13855.6 RLN71867.1 - 1.9e-38 130.1 45.8 5.5e-09 35.6 0.3 9.1 6 3 3 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 RLN71867.1 - 1.5e-28 98.3 46.5 5.5e-05 23.5 0.2 10.8 7 3 2 10 10 10 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN71867.1 - 9.9e-12 44.7 12.7 2.7e-05 23.7 0.3 4.5 2 2 0 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 RLN71867.1 - 2.6e-05 24.2 38.3 2.5 9.0 0.1 13.3 15 2 0 15 15 15 2 Leucine Rich Repeat LRR_6 PF13516.6 RLN71867.1 - 6.1e-05 22.8 40.6 2 8.7 0.2 12.2 13 0 0 13 13 13 3 Leucine Rich repeat LRR_8 PF13855.6 RLN71868.1 - 1.7e-28 98.1 48.9 4.7e-06 26.3 0.6 8.7 4 3 4 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 RLN71868.1 - 5.2e-22 77.6 44.0 0.0008 19.8 0.4 9.7 4 3 9 13 13 13 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN71868.1 - 1.8e-06 27.6 21.2 0.049 13.1 0.3 5.4 3 2 0 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 RLN71868.1 - 5.9e-05 23.1 29.6 4.2 8.3 0.0 11.6 14 1 0 14 14 14 2 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 RLN71868.1 - 0.003 17.6 1.2 11 6.2 0.1 6.0 5 1 1 6 6 6 1 RsmF rRNA methyltransferase first C-terminal domain rRNA_proc-arch PF13234.6 RLN71868.1 - 0.028 14.4 1.4 3.7 7.4 0.1 2.5 2 0 0 2 2 2 0 rRNA-processing arch domain LRR_6 PF13516.6 RLN71868.1 - 0.55 10.4 31.9 5.7 7.3 0.7 9.4 11 0 0 11 11 11 0 Leucine Rich repeat Pkinase_Tyr PF07714.17 RLN71869.1 - 1.8e-107 358.4 0.0 5.2e-54 183.2 0.0 3.6 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 RLN71869.1 - 4.3e-95 318.0 0.0 1.7e-49 168.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 RLN71869.1 - 3e-05 24.1 0.6 0.2 11.5 0.1 2.7 3 0 0 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN71869.1 - 0.00032 19.8 0.3 2.2 7.1 0.1 3.6 4 0 0 4 4 4 2 Haspin like kinase domain NiFe_hyd_3_EhaA PF17367.2 RLN71869.1 - 0.0075 16.4 1.2 0.058 13.5 1.1 2.3 2 0 0 2 2 2 1 NiFe-hydrogenase-type-3 Eha complex subunit A Pkinase_fungal PF17667.1 RLN71869.1 - 0.066 12.0 0.0 4.1 6.1 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase MMR_HSR1 PF01926.23 RLN71870.1 - 2.7e-14 53.2 0.0 3.7e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RLN71870.1 - 2.3e-10 40.6 0.0 8.7e-10 38.7 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 RLN71870.1 - 1.1e-06 28.2 0.5 1e-05 25.1 0.2 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 RLN71870.1 - 0.0071 15.9 0.0 0.72 9.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 RLN71870.1 - 0.012 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 RLN71870.1 - 0.023 15.1 0.0 0.042 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 RLN71870.1 - 0.1 12.9 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 RLN71870.1 - 0.13 12.5 0.0 0.47 10.7 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 RLN71870.1 - 0.14 11.3 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain AAA_18 PF13238.6 RLN71870.1 - 0.15 12.6 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ank_4 PF13637.6 RLN71876.1 - 4.4e-47 157.9 31.2 9.1e-06 26.1 0.1 12.0 6 2 7 13 13 13 13 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN71876.1 - 5.4e-45 151.9 35.1 9.5e-09 35.7 0.2 8.3 3 3 7 10 10 10 10 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN71876.1 - 4.5e-40 135.2 31.7 5.8e-05 23.3 0.2 17.1 2 1 16 18 18 18 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN71876.1 - 3.2e-20 70.1 18.4 1.8 9.4 0.0 16.8 19 0 0 19 19 19 5 Ankyrin repeat DUF5049 PF16468.5 RLN71876.1 - 1.9e-07 30.8 0.3 12 5.8 0.0 8.8 8 3 3 11 11 11 1 Domain of unknown function (DUF5049) Ank PF00023.30 RLN71876.1 - 1.8e-06 28.2 12.1 28 5.4 0.0 11.1 5 4 2 7 7 7 0 Ankyrin repeat VHL_C PF17211.3 RLN71876.1 - 0.044 13.8 0.1 37 4.4 0.0 4.8 5 0 0 5 5 5 0 VHL box domain DUF249 PF03158.13 RLN71876.1 - 0.98 9.1 4.2 73 3.0 0.0 4.8 3 3 0 4 4 4 0 Multigene family 530 protein Myb_DNA-binding PF00249.31 RLN71877.1 - 4.5e-13 49.2 0.1 8.2e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN71877.1 - 0.0043 17.3 0.0 0.0082 16.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain P5-ATPase PF12409.8 RLN71878.1 - 0.13 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 P5-type ATPase cation transporter PASTA PF03793.19 RLN71878.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 PASTA domain Mto2_bdg PF12808.7 RLN71895.1 - 0.11 12.9 8.1 2.4 8.5 2.5 2.5 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Macro PF01661.21 RLN71896.1 - 5.5e-14 52.2 0.0 8.7e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Macro domain GCR1_C PF12550.8 RLN71896.1 - 6.8e-08 32.7 0.0 1.2e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes XRN_N PF03159.18 RLN71897.1 - 7.1e-86 287.6 0.0 1.2e-85 286.8 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 RLN71897.1 - 5.6e-27 94.8 0.1 5.6e-27 94.8 0.1 1.9 2 0 0 2 2 2 1 Xrn1 helical domain HLH PF00010.26 RLN71897.1 - 6.5e-08 32.4 6.2 1.6e-07 31.1 6.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DOPA_dioxygen PF08883.11 RLN71897.1 - 0.6 10.3 3.8 3.1 8.0 3.2 2.4 2 0 0 2 2 2 0 Dopa 4,5-dioxygenase family Ank_2 PF12796.7 RLN71901.1 - 3.1e-34 117.4 4.3 3.2e-12 46.9 0.1 5.7 3 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN71901.1 - 1.1e-33 115.2 2.5 1.5e-12 47.7 0.1 7.7 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 RLN71901.1 - 5.1e-30 102.6 18.4 1.4e-07 31.6 0.2 7.7 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 RLN71901.1 - 2.4e-27 91.9 9.4 1.2e-05 25.3 0.0 8.0 8 1 1 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 RLN71901.1 - 8.8e-21 73.7 9.7 4.7e-10 39.5 0.3 6.2 5 1 1 6 6 6 3 Ankyrin repeats (many copies) TIR_2 PF13676.6 RLN71901.1 - 4.4e-15 56.3 0.0 2.8e-14 53.7 0.0 2.4 2 0 0 2 2 2 1 TIR domain TIR PF01582.20 RLN71901.1 - 0.0046 16.8 0.0 0.0046 16.8 0.0 1.6 2 0 0 2 2 2 1 TIR domain BNIP2 PF12496.8 RLN71901.1 - 5.4 7.5 11.7 8 6.9 6.5 2.8 2 1 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Trypan_PARP PF05887.11 RLN71901.1 - 5.9 6.9 7.8 15 5.5 7.8 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FmiP_Thoc5 PF09766.9 RLN71901.1 - 9 5.5 15.8 2.9 7.1 8.4 2.3 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 ABC_tran PF00005.27 RLN71902.1 - 0.003 18.1 0.1 0.0066 17.0 0.1 1.5 1 0 0 1 1 1 1 ABC transporter Arf PF00025.21 RLN71902.1 - 0.16 11.4 0.1 0.28 10.6 0.1 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family MeaB PF03308.16 RLN71902.1 - 0.19 10.6 0.1 0.29 10.1 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC2_membrane PF01061.24 RLN71903.1 - 1.2e-60 204.5 72.1 1.2e-32 113.0 28.9 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN71903.1 - 1.8e-14 54.4 0.0 2.6e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN71903.1 - 1.3e-05 25.2 0.0 0.038 13.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN71903.1 - 0.0051 16.5 0.5 0.012 15.3 0.5 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN71903.1 - 0.0077 16.7 0.1 0.012 16.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 RLN71903.1 - 0.0086 16.0 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 RLN71903.1 - 0.084 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RLN71903.1 - 0.11 12.0 0.7 0.21 11.1 0.7 1.3 1 0 0 1 1 1 0 AAA domain DUF3160 PF11369.8 RLN71908.1 - 1.8e-82 277.8 0.0 3.6e-82 276.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3160) DUF3160 PF11369.8 RLN71909.1 - 1.8e-14 53.2 0.0 2e-14 53.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3160) LIDHydrolase PF10230.9 RLN71911.1 - 1.4e-50 172.3 0.6 1.8e-50 172.0 0.6 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 RLN71911.1 - 3e-07 30.4 0.0 9.1e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN71911.1 - 3.3e-06 27.9 0.8 3.3e-06 27.9 0.8 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN71911.1 - 1.9e-05 24.1 1.7 2.6e-05 23.6 0.4 1.9 2 1 0 2 2 2 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 RLN71911.1 - 0.012 14.6 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) 3HCDH_N PF02737.18 RLN71912.1 - 5.9e-60 202.2 0.0 7.9e-60 201.8 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 RLN71912.1 - 2.7e-30 104.8 0.1 1.6e-29 102.4 0.0 2.1 2 1 1 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 RLN71912.1 - 9e-05 22.7 2.2 0.00022 21.5 2.2 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 RLN71912.1 - 0.0013 18.1 0.2 0.002 17.5 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 RLN71912.1 - 0.0049 16.5 0.1 0.0074 15.9 0.1 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 RLN71912.1 - 0.067 13.8 1.3 0.14 12.7 1.3 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 RLN71912.1 - 0.086 12.1 0.8 0.13 11.5 0.8 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Myosin_head PF00063.21 RLN71915.1 - 4.8e-79 266.3 0.0 1.7e-70 238.1 0.0 3.4 2 1 0 2 2 2 2 Myosin head (motor domain) PH PF00169.29 RLN71915.1 - 1.8e-06 28.4 0.2 6.7e-06 26.6 0.1 2.1 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 RLN71915.1 - 0.0014 19.0 0.3 0.32 11.5 0.0 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain AAA_22 PF13401.6 RLN71915.1 - 0.0062 16.8 4.1 0.013 15.7 0.0 3.4 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 RLN71915.1 - 0.03 14.7 0.0 0.03 14.7 0.0 3.3 4 0 0 4 4 4 0 AAA ATPase domain AAA_33 PF13671.6 RLN71915.1 - 0.037 14.2 0.0 0.13 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain Glutaredoxin PF00462.24 RLN71915.1 - 0.05 13.8 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin AAA_24 PF13479.6 RLN71915.1 - 0.06 13.1 0.1 0.64 9.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain Arg_repressor PF01316.21 RLN71915.1 - 0.075 12.8 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain AAA_5 PF07728.14 RLN71915.1 - 0.093 12.7 0.0 0.41 10.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PAPA-1 PF04795.12 RLN71915.1 - 0.29 12.0 1.8 0.81 10.5 0.6 2.5 2 0 0 2 2 2 0 PAPA-1-like conserved region Hexapep PF00132.24 RLN71916.1 - 1.8e-16 59.1 19.7 6.1e-06 25.7 3.8 4.3 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 RLN71916.1 - 1.1e-05 25.1 14.0 0.0049 16.6 4.0 4.2 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase CMS1 PF14617.6 RLN71917.1 - 4.1e-27 95.1 0.1 5.6e-27 94.7 0.1 1.2 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 RLN71917.1 - 1.3e-05 25.0 0.0 2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Mito_carr PF00153.27 RLN71918.1 - 1.7e-65 217.0 3.9 2.5e-21 75.4 0.6 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Baculo_PEP_C PF04513.12 RLN71919.1 - 0.062 13.3 0.1 0.38 10.8 0.0 2.4 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1779 PF08680.10 RLN71919.1 - 0.19 11.9 5.3 5.7 7.1 0.7 2.4 2 0 0 2 2 2 0 TATA-box binding TPR_20 PF14561.6 RLN71919.1 - 0.22 11.9 10.9 3.3 8.1 1.6 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat PilJ PF13675.6 RLN71919.1 - 0.4 10.7 4.8 0.48 10.5 0.2 3.1 3 1 1 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term Methyltransf_25 PF13649.6 RLN71919.1 - 1.5 9.6 3.8 2.4 8.9 0.0 3.1 3 2 1 4 4 4 0 Methyltransferase domain ABC_tran PF00005.27 RLN71920.1 - 6.4e-38 130.4 0.0 8.7e-19 68.4 0.0 2.2 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 RLN71920.1 - 1.8e-13 50.0 5.4 4.7e-13 48.7 5.4 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 RLN71920.1 - 2.1e-11 43.7 3.8 0.00031 20.2 1.4 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RLN71920.1 - 8e-10 39.0 6.1 0.15 11.9 0.0 4.2 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 RLN71920.1 - 2.1e-07 30.5 2.9 2.1e-07 30.5 2.9 2.5 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_16 PF13191.6 RLN71920.1 - 1.2e-06 29.0 0.0 0.055 13.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 RLN71920.1 - 2.8e-06 27.3 0.0 0.061 13.0 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 RLN71920.1 - 1.2e-05 25.6 0.2 0.028 14.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain Fer4_6 PF12837.7 RLN71920.1 - 1.5e-05 24.9 2.4 1.5e-05 24.9 2.4 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA PF00004.29 RLN71920.1 - 2.2e-05 24.9 0.0 0.21 12.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 RLN71920.1 - 6.5e-05 22.9 1.6 0.039 13.9 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA_29 PF13555.6 RLN71920.1 - 8e-05 22.3 0.1 0.37 10.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN71920.1 - 0.00022 21.2 0.1 0.55 10.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 RLN71920.1 - 0.00024 21.7 0.0 0.052 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 RLN71920.1 - 0.00058 19.5 1.4 0.13 11.9 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_7 PF12838.7 RLN71920.1 - 0.00065 20.2 6.3 0.0015 19.0 0.6 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 RLN71920.1 - 0.00071 19.5 0.8 0.00071 19.5 0.8 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_5 PF07728.14 RLN71920.1 - 0.00084 19.3 0.5 0.21 11.6 0.0 3.5 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) Fer4_21 PF14697.6 RLN71920.1 - 0.001 19.1 12.0 0.0025 17.9 12.0 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Rad17 PF03215.15 RLN71920.1 - 0.0016 18.4 0.0 0.38 10.6 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain TsaE PF02367.17 RLN71920.1 - 0.0027 17.7 0.3 0.15 12.1 0.1 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_10 PF13237.6 RLN71920.1 - 0.0028 17.7 1.5 0.0028 17.7 1.5 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_33 PF13671.6 RLN71920.1 - 0.0033 17.6 0.0 1.5 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_9 PF13187.6 RLN71920.1 - 0.0033 17.5 11.5 0.0098 16.0 11.6 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain RNA_helicase PF00910.22 RLN71920.1 - 0.0035 17.7 0.0 3.3 8.1 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_24 PF13479.6 RLN71920.1 - 0.0041 16.9 0.3 0.53 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 RLN71920.1 - 0.0051 16.5 0.0 2.5 7.7 0.0 2.7 2 0 0 2 2 2 1 Thymidylate kinase NTPase_1 PF03266.15 RLN71920.1 - 0.007 16.3 0.6 2.1 8.2 0.0 3.6 2 1 1 3 3 3 1 NTPase Fer4_16 PF13484.6 RLN71920.1 - 0.0072 17.2 0.2 0.0072 17.2 0.2 2.6 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain AAA_30 PF13604.6 RLN71920.1 - 0.017 14.8 0.3 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 RLN71920.1 - 0.023 14.4 0.0 5.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E AAA_18 PF13238.6 RLN71920.1 - 0.034 14.7 0.0 5.7 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 RLN71920.1 - 0.042 13.0 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 RLN71920.1 - 0.051 13.8 0.1 17 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RLN71920.1 - 0.08 12.5 0.1 2.2 7.8 0.1 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region MobB PF03205.14 RLN71920.1 - 0.096 12.6 0.9 0.77 9.7 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.23 RLN71920.1 - 0.12 12.5 0.9 21 5.2 0.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_13 PF13166.6 RLN71920.1 - 0.2 10.3 0.3 0.57 8.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain Fer4_4 PF12800.7 RLN71920.1 - 1.1 10.0 14.8 0.24 12.0 3.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 RLN71920.1 - 1.5 9.4 10.6 0.089 13.3 1.2 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 RLN71920.1 - 9.8 6.7 12.0 0.48 10.9 1.6 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Pkinase PF00069.25 RLN71921.1 - 0.016 14.6 0.0 0.016 14.6 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain EphA2_TM PF14575.6 RLN71922.1 - 0.00077 20.3 0.1 0.0021 18.9 0.1 1.8 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 RLN71922.1 - 0.00087 19.0 2.0 0.0018 18.0 2.0 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Shisa PF13908.6 RLN71922.1 - 0.0014 18.9 0.1 0.0014 18.9 0.1 1.8 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Rax2 PF12768.7 RLN71922.1 - 0.0024 17.3 0.3 0.0048 16.4 0.0 1.6 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Amnionless PF14828.6 RLN71922.1 - 0.0032 16.4 0.0 0.0041 16.0 0.0 1.1 1 0 0 1 1 1 1 Amnionless Podoplanin PF05808.11 RLN71922.1 - 0.0048 17.0 0.2 0.01 16.0 0.2 1.6 1 0 0 1 1 1 1 Podoplanin DUF4051 PF13260.6 RLN71922.1 - 0.01 15.5 0.4 0.018 14.7 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Glycophorin_A PF01102.18 RLN71922.1 - 0.026 14.7 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 Glycophorin A TMEM154 PF15102.6 RLN71922.1 - 0.035 14.0 0.0 0.083 12.8 0.0 1.6 1 1 0 1 1 1 0 TMEM154 protein family Syndecan PF01034.20 RLN71922.1 - 0.047 13.6 2.2 0.098 12.6 2.2 1.5 1 0 0 1 1 1 0 Syndecan domain Stevor PF17410.2 RLN71922.1 - 0.098 12.2 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame SKG6 PF08693.10 RLN71922.1 - 0.12 11.8 4.7 0.27 10.7 4.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3430 PF11912.8 RLN71922.1 - 1.1 9.3 20.1 1.9 8.5 19.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3430) MtrF PF09472.10 RLN71922.1 - 5.8 6.4 7.8 11 5.4 7.8 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF3243 PF11588.8 RLN71924.1 - 0.095 13.0 0.2 0.47 10.8 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3243) RecO_N PF11967.8 RLN71924.1 - 0.14 12.2 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Recombination protein O N terminal AMP-binding PF00501.28 RLN71925.1 - 6.1e-78 262.3 0.0 9.2e-77 258.4 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN71925.1 - 6e-15 56.0 0.3 1.4e-14 54.8 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Myb_DNA-bind_4 PF13837.6 RLN71926.1 - 2.2e-05 24.7 0.1 5.5e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 RLN71926.1 - 0.0044 17.1 0.4 0.013 15.5 0.4 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 RLN71926.1 - 0.0083 17.1 1.4 0.016 16.1 0.1 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain SseC PF04888.12 RLN71926.1 - 0.068 12.8 8.9 0.12 12.0 8.9 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Hrs_helical PF12210.8 RLN71926.1 - 0.19 12.3 6.5 0.35 11.4 1.0 2.5 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Com_YlbF PF06133.11 RLN71926.1 - 0.25 12.0 5.7 0.39 11.3 3.1 2.2 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA FlgN PF05130.12 RLN71926.1 - 0.44 11.1 7.9 0.46 11.0 3.7 2.4 2 0 0 2 2 2 0 FlgN protein FAM76 PF16046.5 RLN71926.1 - 1.2 8.5 8.8 0.25 10.7 5.2 1.6 2 0 0 2 2 2 0 FAM76 protein DUF4763 PF15960.5 RLN71926.1 - 2.4 7.4 9.6 2.7 7.2 8.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) DUF1348 PF07080.11 RLN71927.1 - 4.7e-63 210.9 7.3 6e-63 210.6 7.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 RLN71927.1 - 0.00015 22.3 2.0 0.00026 21.6 2.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain HTH_38 PF13936.6 RLN71927.1 - 0.034 13.9 0.3 0.081 12.7 0.3 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Glyco_trans_2_3 PF13632.6 RLN71928.1 - 9.3e-14 51.8 0.0 9.3e-14 51.8 0.0 3.2 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 RLN71928.1 - 6.5e-10 39.3 0.0 1.5e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cellulose_synt PF03552.14 RLN71928.1 - 9.1e-09 34.4 3.0 0.0023 16.5 0.4 3.5 3 1 1 4 4 4 2 Cellulose synthase PH PF00169.29 RLN71928.1 - 3.4e-08 34.0 0.1 7.9e-08 32.8 0.1 1.7 1 0 0 1 1 1 1 PH domain Glycos_transf_2 PF00535.26 RLN71928.1 - 6.4e-08 32.6 0.0 0.012 15.4 0.0 3.3 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 RLN71928.1 - 7.6e-06 25.5 0.0 0.0011 18.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 zf-C6H2 PF15801.5 RLN71928.1 - 0.0021 18.3 9.1 0.0021 18.3 9.1 2.5 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding PH_11 PF15413.6 RLN71928.1 - 0.0037 17.6 0.9 0.012 16.0 0.2 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 RLN71928.1 - 0.021 15.1 0.7 0.17 12.2 0.7 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain PRP1_N PF06424.12 RLN71929.1 - 1.7e-39 135.6 1.3 4.5e-39 134.2 0.1 2.2 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 RLN71929.1 - 6e-25 85.8 27.4 0.035 14.9 0.1 13.8 7 6 8 15 15 15 8 Tetratricopeptide repeat TPR_19 PF14559.6 RLN71929.1 - 6e-22 77.9 9.6 2.4e-06 28.0 0.0 9.4 7 3 4 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.6 RLN71929.1 - 2.4e-07 30.4 5.5 18 5.9 0.0 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN71929.1 - 9.2e-06 26.2 14.1 0.06 14.0 0.1 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN71929.1 - 2.1e-05 24.3 7.1 3.3 8.0 0.0 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN71929.1 - 3.6e-05 23.8 0.1 43 4.8 0.0 8.0 7 2 2 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN71929.1 - 0.082 12.8 0.2 30 4.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.10 RLN71929.1 - 4.8 6.1 10.3 19 4.1 0.2 3.8 3 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) EF-hand_7 PF13499.6 RLN71930.1 - 0.032 14.7 1.9 24 5.5 0.0 4.8 3 1 0 3 3 3 0 EF-hand domain pair Noelin-1 PF12308.8 RLN71930.1 - 0.24 11.4 3.6 6.8 6.7 2.7 3.2 2 0 0 2 2 2 0 Neurogenesis glycoprotein IQ PF00612.27 RLN71930.1 - 0.28 11.1 13.6 0.46 10.4 1.2 3.5 3 0 0 3 3 3 0 IQ calmodulin-binding motif RIBIOP_C PF04950.12 RLN71931.1 - 2.2e-98 329.3 0.5 1.2e-97 326.9 0.0 2.2 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 RLN71931.1 - 4.1e-22 78.1 0.0 1e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain SDA1 PF05285.12 RLN71931.1 - 0.87 9.0 22.8 1.4 8.2 22.8 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RLN71931.1 - 5.5 5.1 19.1 8.8 4.4 19.1 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RLN71931.1 - 9.6 4.4 14.4 15 3.7 14.4 1.3 1 0 0 1 1 1 0 CDC45-like protein ubiquitin PF00240.23 RLN71932.1 - 6.5e-19 67.5 0.0 1.1e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RLN71932.1 - 1.4e-06 28.0 0.0 2.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 RLN71932.1 - 0.0077 16.3 0.0 0.023 14.8 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 RLN71932.1 - 0.028 14.3 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 RLN71932.1 - 0.19 12.2 0.0 0.45 11.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_4 PF18036.1 RLN71932.1 - 0.23 11.5 0.0 2 8.5 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin-like domain Myosin_head PF00063.21 RLN71934.1 - 2.8e-200 667.0 0.0 4e-200 666.5 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) ThiF PF00899.21 RLN71934.1 - 2e-84 282.8 0.0 2.7e-61 207.1 0.0 2.6 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 RLN71934.1 - 1.1e-71 241.7 0.9 1.1e-71 241.7 0.9 1.7 2 0 0 2 2 1 1 Ubiquitin-activating enzyme active site Ank_2 PF12796.7 RLN71934.1 - 9.8e-23 80.6 3.9 8e-10 39.2 0.1 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) E1_4HB PF16191.5 RLN71934.1 - 2.8e-17 62.7 0.0 1.1e-16 60.8 0.0 2.1 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Ank PF00023.30 RLN71934.1 - 3.6e-17 61.9 1.7 0.0016 18.8 0.1 6.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 RLN71934.1 - 1.6e-14 54.0 1.7 0.014 16.0 0.0 5.4 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN71934.1 - 2e-13 49.2 2.3 0.02 15.4 0.0 5.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 RLN71934.1 - 5.1e-12 45.8 2.0 0.00011 22.4 0.0 4.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) E1_FCCH PF16190.5 RLN71934.1 - 1e-08 35.2 0.8 1.4e-06 28.4 0.6 3.9 3 1 0 3 3 3 1 Ubiquitin-activating enzyme E1 FCCH domain FYVE PF01363.21 RLN71934.1 - 3.9e-06 26.9 2.2 9.3e-06 25.7 2.2 1.6 1 0 0 1 1 1 1 FYVE zinc finger E1_UFD PF09358.10 RLN71934.1 - 0.00049 20.7 0.0 0.018 15.7 0.0 2.6 1 1 0 1 1 1 1 Ubiquitin fold domain Tap-RNA_bind PF09162.10 RLN71934.1 - 0.0096 15.7 0.0 0.03 14.1 0.0 1.8 1 0 0 1 1 1 1 Tap, RNA-binding IQ PF00612.27 RLN71934.1 - 0.087 12.7 4.7 2.4 8.2 0.5 2.9 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.6 RLN71934.1 - 0.098 12.9 0.0 0.45 10.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 RLN71934.1 - 0.1 12.9 1.0 0.28 11.5 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 RLN71934.1 - 0.13 12.6 1.4 1.4 9.3 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain Prim-Pol PF09250.11 RLN71934.1 - 0.15 12.4 0.0 24 5.2 0.0 2.6 2 0 0 2 2 2 0 Bifunctional DNA primase/polymerase, N-terminal DSPc PF00782.20 RLN71936.1 - 1.2e-32 112.5 0.0 2.8e-32 111.3 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Palm_thioest PF02089.15 RLN71936.1 - 5.9e-31 108.2 3.8 1.4e-28 100.4 0.4 2.3 1 1 1 2 2 2 2 Palmitoyl protein thioesterase Gelsolin PF00626.22 RLN71936.1 - 0.025 14.5 0.0 0.14 12.1 0.0 2.3 2 0 0 2 2 2 0 Gelsolin repeat Y_phosphatase PF00102.27 RLN71936.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.5 1 1 0 1 1 1 0 Protein-tyrosine phosphatase Pro_isomerase PF00160.21 RLN71937.1 - 3.9e-38 131.2 0.1 4.7e-38 130.9 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ICL PF00463.21 RLN71938.1 - 1.4e-28 99.8 0.3 1.5e-28 99.6 0.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Ad_Cy_reg PF16701.5 RLN71938.1 - 0.013 15.2 0.0 0.015 15.0 0.0 1.0 1 0 0 1 1 1 0 Adenylate cyclase regulatory domain LAL_C2 PF18603.1 RLN71938.1 - 0.093 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 zf-CCCH_3 PF15663.5 RLN71939.1 - 0.054 13.7 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger containing family Arginosuc_synth PF00764.19 RLN71940.1 - 1.6e-153 511.6 0.0 2.4e-153 511.0 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase Rtf2 PF04641.12 RLN71940.1 - 1.2e-60 205.1 21.8 1.7e-59 201.3 19.2 2.5 2 1 0 2 2 2 1 Rtf2 RING-finger ADH_N PF08240.12 RLN71940.1 - 1.6e-25 89.1 0.9 4.6e-25 87.6 0.9 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN71940.1 - 3.9e-21 75.4 1.8 1.3e-20 73.7 0.2 2.6 2 1 1 3 3 3 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN71940.1 - 0.0048 16.3 0.7 0.011 15.1 0.1 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-Nse PF11789.8 RLN71940.1 - 0.038 13.8 0.5 12 5.8 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit QueC PF06508.13 RLN71940.1 - 0.044 13.3 0.0 0.044 13.3 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC AlaDh_PNT_C PF01262.21 RLN71940.1 - 0.065 12.5 0.6 0.13 11.5 0.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 RLN71940.1 - 0.099 12.2 0.4 0.19 11.3 0.4 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Raftlin PF15250.6 RLN71940.1 - 0.85 8.3 9.7 1.3 7.6 9.7 1.2 1 0 0 1 1 1 0 Raftlin Zip PF02535.22 RLN71940.1 - 8 5.6 8.7 12 5.0 8.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter zf-RING_2 PF13639.6 RLN71941.1 - 0.00064 20.0 7.5 0.0011 19.2 7.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 RLN71941.1 - 0.0016 18.4 1.9 0.0016 18.4 1.9 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 RLN71941.1 - 0.0017 18.1 2.2 0.0039 16.9 2.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RLN71941.1 - 0.0052 16.6 7.9 0.0092 15.8 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN71941.1 - 0.0058 16.9 5.2 0.013 15.8 5.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 RLN71941.1 - 0.01 15.6 2.6 0.016 15.1 2.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN71941.1 - 0.24 11.3 4.6 0.45 10.4 4.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN71941.1 - 0.39 10.6 6.9 0.72 9.8 6.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 RLN71941.1 - 0.62 9.7 4.3 1.1 8.9 4.3 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 RLN71941.1 - 0.82 9.7 6.7 2.7 8.0 6.7 1.8 1 1 1 2 2 2 0 zinc-RING finger domain Zn-ribbon_8 PF09723.10 RLN71941.1 - 1.4 9.0 5.5 0.38 10.9 0.6 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-C3H2C3 PF17122.5 RLN71941.1 - 4.2 7.5 8.4 7.5 6.7 8.4 1.4 1 0 0 1 1 1 0 Zinc-finger zf-ANAPC11 PF12861.7 RLN71941.1 - 9.3 6.4 8.0 11 6.2 4.9 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger GST_N_3 PF13417.6 RLN71942.1 - 5.1e-16 58.8 0.0 9.1e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RLN71942.1 - 6.4e-16 58.5 0.0 2e-15 56.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN71942.1 - 2.5e-11 43.7 0.0 4.9e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN71942.1 - 5.1e-05 23.2 0.7 0.0033 17.4 0.7 2.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RLN71942.1 - 0.00021 21.4 0.0 0.00035 20.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RLN71942.1 - 0.00027 21.1 0.0 0.00044 20.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 RLN71942.1 - 0.00092 19.4 0.0 0.0035 17.5 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin GST_C_5 PF16865.5 RLN71942.1 - 0.095 13.3 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain WD40 PF00400.32 RLN71943.1 - 1.2e-18 67.1 4.0 3e-08 34.2 0.1 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN71943.1 - 0.04 14.2 0.0 0.14 12.4 0.0 1.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN71943.1 - 0.14 10.8 0.7 12 4.4 0.0 2.7 1 1 1 3 3 3 0 Nucleoporin Nup120/160 HEAT PF02985.22 RLN71944.1 - 7.3e-35 116.0 39.6 0.00029 20.8 0.0 21.1 23 0 0 23 23 21 8 HEAT repeat HEAT_2 PF13646.6 RLN71944.1 - 2.4e-24 85.6 61.4 0.00028 21.2 0.1 15.3 5 5 10 18 18 18 11 HEAT repeats HEAT_EZ PF13513.6 RLN71944.1 - 1.3e-20 73.4 60.4 0.00022 21.7 0.0 17.7 14 4 5 19 19 18 6 HEAT-like repeat CLASP_N PF12348.8 RLN71944.1 - 3.9e-17 62.6 1.0 4.3e-05 23.2 0.0 9.4 6 2 2 8 8 8 3 CLASP N terminal Cnd1 PF12717.7 RLN71944.1 - 1.6e-15 57.5 10.5 0.27 11.2 0.0 10.5 9 2 1 10 10 10 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 RLN71944.1 - 2.2e-13 50.6 0.1 0.6 10.7 0.0 9.2 9 2 1 11 11 10 3 Vacuolar 14 Fab1-binding region Tti2 PF10521.9 RLN71944.1 - 3.8e-06 26.6 2.6 0.71 9.4 0.0 5.4 4 1 1 5 5 5 2 Tti2 family RTP1_C1 PF10363.9 RLN71944.1 - 1.3e-05 25.4 5.9 1.1 9.4 0.6 6.6 7 1 1 8 8 8 1 Required for nuclear transport of RNA pol II C-terminus 1 NUC173 PF08161.12 RLN71944.1 - 5.3e-05 23.0 0.8 16 5.1 0.0 6.6 6 2 2 8 8 8 0 NUC173 domain Ecm29 PF13001.7 RLN71944.1 - 0.0001 21.1 7.6 0.0048 15.6 0.0 4.8 7 1 0 7 7 7 1 Proteasome stabiliser MMS19_C PF12460.8 RLN71944.1 - 0.00011 21.5 15.0 0.0016 17.6 2.3 6.2 5 2 0 5 5 5 1 RNAPII transcription regulator C-terminal ParcG PF10274.9 RLN71944.1 - 0.00014 22.1 3.3 12 6.0 0.0 6.4 5 2 1 6 6 6 0 Parkin co-regulated protein Adaptin_N PF01602.20 RLN71944.1 - 0.00024 19.8 16.5 0.76 8.3 3.4 7.2 7 1 0 8 8 8 1 Adaptin N terminal region Dopey_N PF04118.14 RLN71944.1 - 0.00039 19.6 0.4 3.1 6.8 0.0 5.4 4 3 1 5 5 5 1 Dopey, N-terminal IFRD PF05004.13 RLN71944.1 - 0.00098 18.3 14.1 0.98 8.5 1.8 5.3 4 2 0 5 5 5 2 Interferon-related developmental regulator (IFRD) DUF3385 PF11865.8 RLN71944.1 - 0.0019 18.1 0.1 33 4.4 0.0 5.3 5 0 0 5 5 5 0 Domain of unknown function (DUF3385) Cohesin_HEAT PF12765.7 RLN71944.1 - 0.23 11.8 24.6 15 6.0 0.0 9.6 10 0 0 10 10 10 0 HEAT repeat associated with sister chromatid cohesion ADSL_C PF10397.9 RLN71944.1 - 0.24 11.9 1.7 59 4.3 0.0 4.0 3 0 0 3 3 2 0 Adenylosuccinate lyase C-terminus Caerin_1 PF07440.12 RLN71944.1 - 0.36 11.0 4.1 17 5.6 0.4 3.3 2 0 0 2 2 2 0 Caerin 1 protein DNA_pol_E_B PF04042.16 RLN71945.1 - 9.8e-43 146.0 0.0 2e-42 144.9 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos PF00149.28 RLN71945.1 - 0.016 15.7 0.7 0.035 14.6 0.0 1.9 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase TPR_2 PF07719.17 RLN71945.1 - 0.18 12.0 8.9 1.5 9.1 0.6 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN71945.1 - 2.5 9.1 15.6 0.12 13.2 0.9 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN71945.1 - 5 7.1 10.0 0.29 11.0 0.7 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4658 PF15555.6 RLN71946.1 - 0.17 12.0 0.7 7.9 6.6 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) SH3_3 PF08239.11 RLN71947.1 - 3.4e-09 36.8 0.7 0.012 15.9 0.0 3.4 3 0 0 3 3 3 2 Bacterial SH3 domain Stc1 PF12898.7 RLN71947.1 - 7e-06 26.5 13.3 0.0015 19.0 2.6 2.6 1 1 1 2 2 2 2 Stc1 domain FYVE PF01363.21 RLN71947.1 - 0.54 10.4 8.4 0.092 12.9 2.9 2.5 3 0 0 3 3 3 0 FYVE zinc finger RBD PF02196.15 RLN71948.1 - 0.0032 17.5 0.0 0.67 10.1 0.1 2.7 2 0 0 2 2 2 2 Raf-like Ras-binding domain Prenyltransf PF01255.19 RLN71949.1 - 5.3e-70 235.4 0.0 6.4e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Cid2 PF09774.9 RLN71949.1 - 0.018 15.5 0.0 0.027 14.9 0.0 1.2 1 0 0 1 1 1 0 Caffeine-induced death protein 2 PLDc_2 PF13091.6 RLN71949.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 PLD-like domain IGPS PF00218.21 RLN71950.1 - 2.3e-45 154.8 1.8 2.6e-24 85.8 0.1 4.1 4 1 0 4 4 4 2 Indole-3-glycerol phosphate synthase PRAI PF00697.22 RLN71950.1 - 6.7e-40 136.9 0.1 6.4e-35 120.7 0.0 2.4 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Myb_DNA-binding PF00249.31 RLN71950.1 - 7.6e-12 45.2 0.1 1.2e-09 38.2 0.0 3.4 3 0 0 3 3 3 1 Myb-like DNA-binding domain SWIRM PF04433.17 RLN71950.1 - 2.5e-10 40.6 0.0 8.8e-10 38.8 0.0 2.0 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 RLN71950.1 - 0.00079 19.6 0.0 0.0024 18.1 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C4H2 PF10146.9 RLN71950.1 - 0.26 11.6 3.2 0.81 10.0 3.2 1.8 1 0 0 1 1 1 0 Zinc finger-containing protein zf-B_box PF00643.24 RLN71950.1 - 0.84 9.8 3.5 2.5 8.3 3.5 1.8 1 1 0 1 1 1 0 B-box zinc finger DZR PF12773.7 RLN71950.1 - 1 9.4 3.2 2.9 8.0 3.2 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-UBR PF02207.20 RLN71950.1 - 1.1 9.5 5.0 2.3 8.5 5.0 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Methyltransf_4 PF02390.17 RLN71951.1 - 1.1e-37 129.1 0.0 1.3e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 RLN71951.1 - 9.9e-07 28.7 0.0 1.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN71951.1 - 1.6e-06 28.7 0.0 3.1e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN71951.1 - 8.8e-05 23.2 0.0 0.00017 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN71951.1 - 0.0012 19.5 0.0 0.0026 18.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN71951.1 - 0.0083 16.0 0.0 0.014 15.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PG_binding_3 PF09374.10 RLN71951.1 - 0.034 14.4 0.0 0.099 12.9 0.0 1.8 2 0 0 2 2 2 0 Predicted Peptidoglycan domain Methyltransf_33 PF10017.9 RLN71951.1 - 0.058 12.5 0.0 0.076 12.2 0.0 1.1 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Ubie_methyltran PF01209.18 RLN71951.1 - 0.073 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family SDF PF00375.18 RLN71952.1 - 8.3e-76 255.5 35.7 6.7e-75 252.5 35.7 1.9 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family Fascin PF06268.13 RLN71952.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Fascin domain LRR_8 PF13855.6 RLN71953.1 - 1.8e-05 24.4 14.1 0.081 12.7 0.0 6.8 5 2 0 5 5 5 3 Leucine rich repeat LRR_6 PF13516.6 RLN71953.1 - 5.4e-05 22.9 16.6 0.37 11.0 0.0 7.5 9 0 0 9 9 9 2 Leucine Rich repeat LRR_1 PF00560.33 RLN71953.1 - 0.00069 19.8 13.8 2.4 9.0 0.0 6.9 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_4 PF12799.7 RLN71953.1 - 0.0021 18.5 14.9 2.9 8.5 0.1 6.3 6 1 0 6 6 6 2 Leucine Rich repeats (2 copies) Phage_CI_C PF16452.5 RLN71954.1 - 2.1e-06 27.9 2.5 51 4.2 0.0 7.2 1 1 7 8 8 8 3 Bacteriophage CI repressor C-terminal domain Pirin_C PF05726.13 RLN71954.1 - 0.042 14.2 0.3 26 5.3 0.0 3.3 1 1 3 4 4 4 0 Pirin C-terminal cupin domain Fas_alpha_ACP PF18325.1 RLN71955.1 - 1e-97 325.1 0.1 1.5e-47 162.0 0.0 2.4 2 0 0 2 2 2 2 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 RLN71955.1 - 5.8e-41 140.4 0.1 3.9e-25 88.7 0.4 2.5 1 1 0 2 2 2 2 Fatty acid synthase type I helical domain adh_short PF00106.25 RLN71955.1 - 1.4e-07 31.1 0.0 1.4e-07 31.1 0.0 2.4 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN71955.1 - 2e-06 27.6 5.3 6.3e-06 25.9 0.0 3.3 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase NYD-SP12_N PF15015.6 RLN71955.1 - 0.001 17.6 0.3 0.0016 16.9 0.3 1.1 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal Tankyrase_bdg_C PF15327.6 RLN71955.1 - 0.0071 16.8 1.3 0.016 15.7 1.3 1.5 1 0 0 1 1 1 1 Tankyrase binding protein C terminal domain GDP_Man_Dehyd PF16363.5 RLN71955.1 - 0.012 15.0 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sigma70_ner PF04546.13 RLN71955.1 - 0.28 11.0 3.9 0.64 9.9 3.9 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region AA_permease_2 PF13520.6 RLN71956.1 - 1.3e-36 126.4 42.9 1.7e-36 126.0 42.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN71956.1 - 3.9e-28 98.3 40.9 5.1e-28 97.9 40.9 1.1 1 0 0 1 1 1 1 Amino acid permease UCR_14kD PF02271.16 RLN71958.1 - 8.5e-22 77.0 0.6 8.5e-22 77.0 0.6 2.0 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase complex 14kD subunit YL1 PF05764.13 RLN71958.1 - 0.011 15.8 14.5 0.017 15.3 14.5 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Apt1 PF10351.9 RLN71958.1 - 0.54 9.0 4.6 0.71 8.7 4.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4746 PF15928.5 RLN71958.1 - 3.3 7.1 7.4 2.4 7.5 5.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4746) AAA_6 PF12774.7 RLN71959.1 - 8.2e-130 432.5 0.5 1.2e-113 379.5 0.0 3.4 2 1 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN71959.1 - 1.4e-118 396.5 5.4 2e-117 392.7 0.1 3.8 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RLN71959.1 - 2e-74 250.2 0.0 5.4e-74 248.8 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RLN71959.1 - 6.5e-73 244.5 6.1 6.5e-73 244.5 6.1 3.1 3 0 0 3 3 3 1 ATP-binding dynein motor region Dynein_C PF18199.1 RLN71959.1 - 4.4e-69 233.0 3.3 7.7e-68 229.0 0.8 2.8 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 RLN71959.1 - 5.6e-52 175.9 0.2 6.4e-44 149.6 0.0 5.3 5 1 0 5 5 5 2 P-loop containing dynein motor region MT PF12777.7 RLN71959.1 - 7.1e-51 173.2 11.7 1.4e-50 172.3 11.7 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RLN71959.1 - 6.5e-42 142.4 0.2 6e-39 132.8 0.0 4.0 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 RLN71959.1 - 1.5e-37 128.9 0.0 6.1e-37 127.0 0.0 2.1 1 1 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 RLN71959.1 - 8.7e-16 58.2 0.0 4.1e-15 56.0 0.0 2.3 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RLN71959.1 - 1.5e-14 54.2 0.2 0.00028 20.9 0.0 6.2 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 RLN71959.1 - 1.3e-11 45.2 9.2 0.00051 20.6 0.0 7.5 7 0 0 7 7 7 2 AAA domain AAA_lid_1 PF17857.1 RLN71959.1 - 1.4e-10 41.2 0.0 2.7e-09 37.1 0.0 3.1 2 1 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 RLN71959.1 - 3.2e-08 33.9 9.6 0.07 13.4 0.0 6.2 6 0 0 6 6 4 2 AAA domain AAA PF00004.29 RLN71959.1 - 8.8e-07 29.4 0.3 0.019 15.4 0.0 4.4 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 RLN71959.1 - 4.6e-06 26.3 0.2 0.076 12.8 0.0 3.5 3 0 0 3 3 3 2 P-loop containing region of AAA domain T2SSE PF00437.20 RLN71959.1 - 0.00018 20.7 1.1 0.072 12.1 0.0 3.2 3 0 0 3 3 2 1 Type II/IV secretion system protein ABC_tran PF00005.27 RLN71959.1 - 0.00026 21.5 0.1 3.8 8.0 0.0 4.1 3 0 0 3 3 3 1 ABC transporter AAA_33 PF13671.6 RLN71959.1 - 0.00028 21.1 0.2 0.55 10.4 0.0 4.1 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 RLN71959.1 - 0.00033 20.9 0.1 12 6.1 0.0 4.1 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 RLN71959.1 - 0.00042 20.7 0.0 18 5.8 0.0 3.8 3 0 0 3 3 3 0 RNA helicase AAA_16 PF13191.6 RLN71959.1 - 0.0015 19.0 18.5 0.14 12.5 0.1 6.9 6 1 1 7 7 6 1 AAA ATPase domain DUF815 PF05673.13 RLN71959.1 - 0.0082 15.3 0.1 3.9 6.6 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Rad17 PF03215.15 RLN71959.1 - 0.0089 16.0 0.1 25 4.7 0.0 3.7 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_30 PF13604.6 RLN71959.1 - 0.028 14.2 12.1 0.38 10.5 0.0 4.8 4 0 0 4 4 3 0 AAA domain NACHT PF05729.12 RLN71959.1 - 0.054 13.4 0.7 5.6 6.9 0.0 3.7 3 0 0 3 3 2 0 NACHT domain Sec34 PF04136.15 RLN71959.1 - 0.082 12.8 6.2 0.19 11.6 1.4 3.4 2 0 0 2 2 2 0 Sec34-like family Zeta_toxin PF06414.12 RLN71959.1 - 0.085 12.1 0.2 11 5.3 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin Sigma54_activat PF00158.26 RLN71959.1 - 0.11 12.2 0.1 3.7 7.2 0.0 3.0 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_21 PF13304.6 RLN71959.1 - 0.13 12.1 0.0 4.9 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 RLN71959.1 - 0.14 12.3 0.0 8.3 6.5 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 RLN71959.1 - 0.17 12.0 3.2 8.4 6.4 0.0 3.7 3 0 0 3 3 3 0 Helicase HerA, central domain Viral_helicase1 PF01443.18 RLN71959.1 - 0.37 10.5 3.0 7.1 6.3 0.0 3.3 4 0 0 4 4 2 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 RLN71959.1 - 1.5 8.9 3.6 27 4.8 0.0 3.5 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CC2-LZ PF16516.5 RLN71959.1 - 4.5 7.7 9.4 29 5.1 5.8 3.6 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF3128 PF11326.8 RLN71960.1 - 2.4e-18 66.3 1.0 3.6e-18 65.7 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Sec2p PF06428.11 RLN71961.1 - 0.055 13.5 0.3 0.071 13.1 0.3 1.1 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Kisspeptin PF15152.6 RLN71962.1 - 3.8 8.4 5.6 1.2 10.0 1.2 2.5 2 0 0 2 2 2 0 Kisspeptin DP PF08781.10 RLN71963.1 - 9.5e-32 109.8 1.4 1.4e-31 109.2 1.4 1.3 1 0 0 1 1 1 1 Transcription factor DP HECT PF00632.25 RLN71965.1 - 3.2e-56 191.1 0.0 8.3e-56 189.7 0.0 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 RLN71965.1 - 0.0005 19.3 14.9 0.0027 17.0 1.2 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 RLN71965.1 - 0.21 11.0 7.8 2.9 7.3 0.6 2.8 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DZR PF12773.7 RLN71965.1 - 2.6 8.1 7.8 5.6 7.1 7.8 1.6 1 0 0 1 1 1 0 Double zinc ribbon Bromodomain PF00439.25 RLN71966.1 - 1.2e-20 73.4 0.1 2.5e-20 72.3 0.1 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 RLN71966.1 - 2.7e-10 40.5 0.0 5.8e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RLN71966.1 - 3.1e-08 33.6 0.0 7.1e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN71966.1 - 1.3e-05 25.5 0.2 2.6e-05 24.5 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN71966.1 - 0.07 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein SET PF00856.28 RLN71966.1 - 2.3 8.6 5.9 21 5.4 5.7 2.5 1 1 0 1 1 1 0 SET domain Vps52 PF04129.12 RLN71967.1 - 5.5e-124 414.7 14.5 4.8e-122 408.3 14.5 2.3 1 1 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 RLN71967.1 - 1.3e-10 40.4 18.9 7.4e-10 37.9 11.3 2.1 2 0 0 2 2 2 2 Exocyst complex component Sec3 SPX PF03105.19 RLN71968.1 - 4.8e-21 76.1 4.2 6.8e-14 52.6 2.4 2.5 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 RLN71968.1 - 5e-11 42.3 4.1 5e-11 42.3 4.1 2.5 1 1 2 3 3 3 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 RLN71968.1 - 2.4e-06 27.0 18.8 1.7e-05 24.2 18.8 2.1 1 1 0 1 1 1 1 Citrate transporter Phage_Capsid_P3 PF09018.11 RLN71968.1 - 0.11 11.3 0.3 0.18 10.6 0.3 1.3 1 0 0 1 1 1 0 P3 major capsid protein PRA1 PF03208.19 RLN71968.1 - 0.62 9.7 20.1 0.064 12.9 8.8 3.0 2 1 1 3 3 3 0 PRA1 family protein LRR_4 PF12799.7 RLN71969.1 - 0.0065 16.9 0.1 0.036 14.5 0.1 2.3 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN71969.1 - 0.076 13.6 1.0 1.5e+02 3.6 0.1 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 RLN71969.1 - 0.1 12.7 0.3 41 4.6 0.1 3.8 4 0 0 4 4 4 0 Leucine Rich repeat Phosphodiest PF01663.22 RLN71970.1 - 1.6e-10 41.2 0.1 2.6e-10 40.4 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RLN71970.1 - 9.9e-05 21.9 0.1 0.00057 19.4 0.0 2.0 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 RLN71970.1 - 0.014 14.8 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily HECT PF00632.25 RLN71971.1 - 1.6e-56 192.1 0.0 2.1e-56 191.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) F-box-like_2 PF13013.6 RLN71971.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain UCH PF00443.29 RLN71972.1 - 9e-43 146.6 0.0 2.9e-42 145.0 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN71972.1 - 1.9e-13 50.7 0.0 1.8e-09 37.7 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 RLN71972.1 - 0.007 16.1 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family LRR_4 PF12799.7 RLN71973.1 - 1.4e-13 50.8 2.6 6.3e-05 23.3 0.0 3.9 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN71973.1 - 6.5e-11 41.8 7.1 0.00031 20.4 0.7 3.9 2 1 1 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 RLN71973.1 - 2.5e-07 30.4 0.5 8.5e-07 28.6 0.5 1.7 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 RLN71973.1 - 0.0003 20.9 6.5 38 5.4 0.1 6.7 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 RLN71973.1 - 0.64 10.2 13.6 18 5.7 0.0 5.6 7 0 0 7 7 7 0 Leucine Rich repeat DEAD PF00270.29 RLN71974.1 - 3.7e-30 105.0 0.1 2.1e-29 102.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN71974.1 - 8.7e-26 90.4 0.1 1.6e-25 89.6 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN71974.1 - 0.00032 20.7 0.0 0.00056 19.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 RLN71974.1 - 0.065 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain fragilysinNterm PF16376.5 RLN71974.1 - 0.077 12.7 0.1 0.36 10.6 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain of fragilysin WD40 PF00400.32 RLN71975.1 - 2.7e-29 100.8 18.6 1.7e-06 28.6 0.1 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat NLE PF08154.12 RLN71975.1 - 9.9e-22 77.2 0.0 1.7e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 RLN71975.1 - 3.7e-07 29.2 3.8 0.011 14.4 0.2 3.5 1 1 2 4 4 4 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 RLN71975.1 - 0.00013 22.2 4.7 0.048 14.0 0.2 4.1 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 RLN71975.1 - 0.048 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus MDMPI_C PF07398.11 RLN71975.1 - 9.6 7.2 9.3 0.49 11.3 0.4 3.3 3 1 0 3 3 3 0 MDMPI C-terminal domain Glyco_hydro_72 PF03198.14 RLN71976.1 - 3.8e-06 26.4 0.0 1.2e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Glucanosyltransferase FeoB_Cyto PF17910.1 RLN71977.1 - 0.1 13.2 2.8 0.26 11.9 0.3 2.5 3 0 0 3 3 3 0 FeoB cytosolic helical domain MHB PF16525.5 RLN71977.1 - 0.13 12.5 0.1 0.49 10.7 0.1 2.0 1 0 0 1 1 1 0 Haemophore, haem-binding DUF445 PF04286.12 RLN71977.1 - 0.32 10.8 3.2 0.62 9.8 3.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF1002 PF06207.11 RLN71977.1 - 0.92 9.0 3.7 0.56 9.7 1.7 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1002) YbjQ_1 PF01906.17 RLN71977.1 - 2.3 8.9 4.4 0.68 10.6 0.2 2.2 3 0 0 3 3 3 0 Putative heavy-metal-binding TPR_14 PF13428.6 RLN71978.1 - 6.2e-06 26.6 15.8 0.38 11.7 0.1 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN71978.1 - 2e-05 24.8 3.7 0.43 10.8 0.1 3.8 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 RLN71978.1 - 0.00018 21.3 16.3 0.019 15.1 0.0 5.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN71978.1 - 0.00099 18.7 0.7 1.1 9.0 0.0 3.0 2 0 0 2 2 2 2 TPR repeat TPR_19 PF14559.6 RLN71978.1 - 0.0064 17.0 7.2 0.28 11.7 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN71978.1 - 0.0079 16.3 2.8 0.16 12.2 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN71978.1 - 0.027 15.1 2.8 14 6.6 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN71978.1 - 0.31 10.9 6.0 5 7.1 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN71979.1 - 6.1e-18 63.8 7.7 1e-09 37.8 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN71979.1 - 4.8e-14 51.3 13.2 5.1e-08 32.4 0.2 3.6 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN71979.1 - 2.9e-12 45.8 6.1 3.2e-05 23.8 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN71979.1 - 2e-09 37.0 4.1 4.8e-06 26.1 0.1 3.0 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.6 RLN71979.1 - 9e-08 32.3 8.4 0.00014 22.3 0.0 3.9 2 1 3 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN71979.1 - 9.8e-08 31.9 6.0 0.00044 20.4 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN71979.1 - 4.1e-05 23.3 2.1 0.61 10.0 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN71979.1 - 5.1e-05 23.3 3.1 0.11 12.6 0.0 2.5 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN71979.1 - 0.00032 21.3 8.6 0.0025 18.5 0.1 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN71979.1 - 0.00046 20.4 8.2 0.018 15.3 0.3 3.0 2 1 1 3 3 2 2 Tetratricopeptide repeat NARP1 PF12569.8 RLN71979.1 - 0.00048 19.2 1.2 0.048 12.6 0.5 2.0 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 RLN71979.1 - 0.0011 18.9 1.0 0.023 14.7 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 RLN71979.1 - 0.0029 16.8 4.9 0.022 14.0 0.1 2.5 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN71979.1 - 0.0058 17.1 0.3 0.19 12.2 0.3 2.8 1 1 3 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN71979.1 - 0.053 13.8 2.6 0.17 12.1 1.6 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_WDAD PF04053.14 RLN71979.1 - 0.054 12.5 0.1 0.078 12.0 0.1 1.2 1 0 0 1 1 1 0 Coatomer WD associated region MIT PF04212.18 RLN71979.1 - 0.056 13.5 0.4 0.056 13.5 0.4 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain ChAPs PF09295.10 RLN71979.1 - 0.11 11.5 0.2 0.11 11.5 0.2 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.17 RLN71979.1 - 0.15 12.5 4.0 7.4 7.0 0.0 2.5 1 1 0 2 2 2 0 Bacterial transcriptional activator domain NRBF2_MIT PF17169.4 RLN71979.1 - 0.28 11.4 3.6 0.46 10.7 0.3 2.2 1 1 1 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 TPR_6 PF13174.6 RLN71979.1 - 0.95 10.2 0.0 0.95 10.2 0.0 3.2 3 1 0 3 3 2 0 Tetratricopeptide repeat PspA_IM30 PF04012.12 RLN71979.1 - 1.5 8.3 5.7 0.25 10.9 1.1 1.9 1 1 0 2 2 2 0 PspA/IM30 family WD40 PF00400.32 RLN71980.1 - 2.1e-32 110.6 0.8 1e-07 32.5 0.1 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN71980.1 - 3.8e-05 23.9 0.0 2.7 8.4 0.0 3.8 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN71980.1 - 0.0017 17.1 0.2 0.76 8.4 0.0 3.5 4 0 0 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 RLN71980.1 - 0.007 16.4 0.0 6.3 6.9 0.0 3.0 2 2 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region FYVE PF01363.21 RLN71981.1 - 0.02 15.1 9.7 0.047 13.8 9.7 1.7 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN71981.1 - 0.51 10.6 6.1 0.25 11.5 3.0 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger C1_2 PF03107.16 RLN71981.1 - 0.52 10.7 6.4 1.5 9.2 6.4 1.8 1 1 0 1 1 1 0 C1 domain Profilin PF00235.19 RLN71982.1 - 0.00092 19.5 0.0 0.0024 18.1 0.0 1.8 1 1 0 1 1 1 1 Profilin Retinal PF15449.6 RLN71982.1 - 7.4 4.2 10.3 9.8 3.8 10.3 1.0 1 0 0 1 1 1 0 Retinal protein Spc7 PF08317.11 RLN71983.1 - 0.0021 17.0 16.8 0.0021 17.0 16.8 5.3 2 1 3 5 5 5 4 Spc7 kinetochore protein Cnn_1N PF07989.11 RLN71983.1 - 0.043 14.0 0.2 0.043 14.0 0.2 9.0 7 3 2 10 10 10 0 Centrosomin N-terminal motif 1 Lipoxygenase PF00305.19 RLN71984.1 - 3.6e-15 55.5 0.0 8.2e-07 27.8 0.0 2.1 2 0 0 2 2 2 2 Lipoxygenase 2OG-FeII_Oxy_3 PF13640.6 RLN71985.1 - 3.5e-15 56.6 0.1 1.4e-14 54.7 0.1 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TPPK_C PF12555.8 RLN71985.1 - 0.07 13.2 1.6 0.14 12.2 1.6 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal RskA PF10099.9 RLN71985.1 - 0.096 13.0 3.9 0.43 10.9 4.5 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Hydrophobin_2 PF06766.11 RLN71985.1 - 0.18 11.8 0.2 0.34 10.9 0.2 1.4 1 0 0 1 1 1 0 Fungal hydrophobin DUF1084 PF06454.11 RLN71986.1 - 1.3e-06 28.0 11.5 0.00015 21.3 11.5 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) WW PF00397.26 RLN71987.1 - 3.9e-05 23.6 3.5 0.00011 22.2 3.5 1.8 1 1 0 1 1 1 1 WW domain Pkinase_Tyr PF07714.17 RLN71989.1 - 1.9e-21 76.5 0.0 7.1e-09 35.3 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase LRR_8 PF13855.6 RLN71989.1 - 5.1e-11 42.2 9.7 2.5e-07 30.4 1.3 3.4 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 RLN71989.1 - 2.1e-08 34.3 11.7 0.039 14.4 0.7 4.1 2 1 1 4 4 4 4 Leucine Rich repeats (2 copies) Pkinase PF00069.25 RLN71989.1 - 0.0012 18.3 0.0 15 4.9 0.0 3.5 3 1 0 3 3 3 3 Protein kinase domain LRR_9 PF14580.6 RLN71989.1 - 0.0026 17.3 0.1 0.037 13.5 0.0 2.1 1 1 1 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 RLN71989.1 - 0.034 14.7 1.6 46 5.1 0.1 4.5 3 1 0 3 3 3 0 Leucine Rich Repeat OrfB_Zn_ribbon PF07282.11 RLN71990.1 - 6.6 6.7 9.3 1.4 8.9 4.7 2.3 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Asp PF00026.23 RLN71991.1 - 7.7e-22 78.1 0.0 2.1e-14 53.7 0.0 2.9 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 RLN71991.1 - 1.2e-06 28.9 5.3 0.0013 19.0 0.0 3.3 3 1 1 4 4 4 2 Xylanase inhibitor N-terminal PLAC8 PF04749.17 RLN71991.1 - 0.00056 20.9 5.2 0.00056 20.9 5.2 1.9 2 0 0 2 2 2 1 PLAC8 family TAXi_C PF14541.6 RLN71991.1 - 0.01 15.7 0.0 2.5 7.9 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 RLN71991.1 - 0.021 15.4 0.0 0.91 10.2 0.0 2.5 2 0 0 2 2 2 0 Aspartyl protease SDF PF00375.18 RLN71992.1 - 1e-28 100.5 16.8 8.4e-28 97.5 16.8 1.9 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family Activator_LAG-3 PF11498.8 RLN71992.1 - 0.096 11.6 9.5 0.16 10.9 9.5 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.13 RLN71992.1 - 2 8.4 6.2 3.2 7.7 6.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PLAC8 PF04749.17 RLN71994.1 - 2.3e-07 31.7 4.1 8.5e-07 29.9 3.8 2.2 2 1 0 2 2 2 1 PLAC8 family fn3 PF00041.21 RLN71996.1 - 4e-56 187.3 13.3 7.2e-10 39.1 0.0 11.7 11 0 0 11 11 11 8 Fibronectin type III domain PA14 PF07691.12 RLN71996.1 - 8.4e-43 145.7 0.0 3.5e-21 75.6 0.0 2.6 2 0 0 2 2 2 2 PA14 domain Filamin PF00630.19 RLN71996.1 - 2.9e-16 60.2 0.2 1.4e-07 32.2 0.0 7.2 7 0 0 7 7 7 2 Filamin/ABP280 repeat Pur_ac_phosph_N PF16656.5 RLN71996.1 - 9.7e-15 54.9 1.7 0.012 16.1 0.0 8.1 7 0 0 7 7 7 3 Purple acid Phosphatase, N-terminal domain POTRA_1 PF08478.10 RLN71996.1 - 1.1e-06 28.8 0.2 7 7.0 0.0 6.1 5 0 0 5 5 5 1 POTRA domain, FtsQ-type GLEYA PF10528.9 RLN71996.1 - 1.6e-06 28.4 0.0 0.031 14.7 0.0 4.2 3 0 0 3 3 3 2 GLEYA domain DUF2369 PF10179.9 RLN71996.1 - 0.0019 18.6 0.6 22 5.5 0.0 5.5 6 0 0 6 6 6 1 Uncharacterised conserved protein (DUF2369) SusE PF14292.6 RLN71996.1 - 0.0021 18.3 14.9 0.41 10.9 1.2 7.1 7 1 1 8 8 8 2 SusE outer membrane protein Patatin PF01734.22 RLN71997.1 - 5.9e-23 82.1 0.0 1.2e-22 81.1 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3336 PF11815.8 RLN71997.1 - 2.2e-09 37.1 0.7 1.5e-08 34.4 0.1 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF3336) YafO_toxin PF13957.6 RLN71998.1 - 0.00021 21.3 2.4 0.00095 19.2 2.4 2.2 1 0 0 1 1 1 1 Toxin YafO, type II toxin-antitoxin system DUF16 PF01519.16 RLN71998.1 - 0.028 14.9 6.0 0.028 14.9 6.0 4.8 2 1 1 3 3 3 0 Protein of unknown function DUF16 SlyX PF04102.12 RLN71998.1 - 0.035 14.7 3.9 0.035 14.7 3.9 7.2 4 1 3 7 7 7 0 SlyX VPS11_C PF12451.8 RLN71998.1 - 0.42 10.9 5.6 2 8.7 0.9 4.0 3 0 0 3 3 3 0 Vacuolar protein sorting protein 11 C terminal DUF948 PF06103.11 RLN71998.1 - 4.1 7.7 7.1 4.6 7.6 3.8 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) SLATT_1 PF18181.1 RLN71999.1 - 0.029 14.3 0.2 0.034 14.1 0.2 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 MtN3_slv PF03083.16 RLN72000.1 - 3.3e-31 107.2 18.6 8.5e-24 83.4 1.8 2.6 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RLN72000.1 - 1.7 8.4 10.6 2.4 8.0 0.1 3.7 4 0 0 4 4 4 0 PQ loop repeat LIDHydrolase PF10230.9 RLN72000.1 - 4.1 6.9 4.5 0.8 9.2 1.0 1.5 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Ank_2 PF12796.7 RLN72001.1 - 2.9e-36 123.9 5.4 1.4e-06 28.8 0.0 6.9 2 2 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN72001.1 - 1.5e-35 121.1 24.3 7.7e-05 23.2 0.3 11.9 7 4 7 14 14 14 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN72001.1 - 4.2e-23 81.1 24.9 0.0041 17.4 0.2 14.7 4 1 13 17 17 17 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN72001.1 - 5e-17 60.3 7.3 13 6.7 0.0 14.6 14 3 3 17 17 17 2 Ankyrin repeat DUF5049 PF16468.5 RLN72001.1 - 0.00027 20.8 0.0 22 5.0 0.0 6.1 5 2 3 8 8 8 0 Domain of unknown function (DUF5049) Rad17 PF03215.15 RLN72001.1 - 0.2 11.6 0.0 0.6 10.0 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain Ank PF00023.30 RLN72001.1 - 0.47 11.0 5.7 3.7e+02 1.9 0.8 7.4 6 3 2 8 8 8 0 Ankyrin repeat DUF1987 PF09345.10 RLN72001.1 - 0.97 9.1 3.8 28 4.4 0.0 4.7 7 0 0 7 7 7 0 Domain of unknown function (DUF1987) MtN3_slv PF03083.16 RLN72002.1 - 7.6e-94 307.9 52.7 4.6e-23 81.1 4.4 6.7 6 0 0 6 6 6 6 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RLN72002.1 - 0.001 18.8 28.1 0.15 11.9 0.8 7.4 7 1 1 8 8 8 4 PQ loop repeat Cytochrom_B_C PF00032.17 RLN72002.1 - 0.0024 18.1 32.9 3.2 8.1 0.4 7.1 4 3 3 7 7 7 5 Cytochrome b(C-terminal)/b6/petD DUF4124 PF13511.6 RLN72002.1 - 0.19 12.1 0.1 11 6.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4124) YmcE_antitoxin PF15939.5 RLN72002.1 - 0.61 10.3 4.4 15 5.8 0.7 2.9 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system Ank_4 PF13637.6 RLN72003.1 - 3.7e-36 123.0 23.0 0.00017 22.1 0.1 11.7 8 4 3 11 11 11 10 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN72003.1 - 3.4e-33 114.1 9.9 3.1e-06 27.7 0.0 7.6 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN72003.1 - 2e-31 107.7 24.6 0.033 14.5 0.1 15.5 4 3 13 17 17 17 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN72003.1 - 1e-19 68.5 3.6 14 6.7 0.0 14.3 16 0 0 16 16 16 1 Ankyrin repeat Ank PF00023.30 RLN72003.1 - 1.6e-05 25.1 3.0 27 5.4 0.1 8.4 6 2 1 7 7 7 0 Ankyrin repeat DUF1843 PF08898.10 RLN72003.1 - 0.00012 22.5 16.9 1.4 9.5 0.0 9.4 11 1 1 12 12 12 1 Domain of unknown function (DUF1843) DUF3322 PF11795.8 RLN72003.1 - 0.00043 20.3 2.7 19 5.2 0.0 5.3 2 2 3 6 6 6 2 Uncharacterized protein conserved in bacteria N-term (DUF3322) DUF5049 PF16468.5 RLN72003.1 - 0.00061 19.6 0.0 46 4.0 0.0 6.1 5 1 2 7 7 7 0 Domain of unknown function (DUF5049) Myb_DNA-bind_4 PF13837.6 RLN72004.1 - 9.3e-06 25.9 0.0 0.027 14.8 0.0 3.1 2 1 1 3 3 3 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 RLN72004.1 - 0.00031 20.8 1.6 0.8 9.8 0.1 3.6 3 1 0 3 3 3 2 Myb/SANT-like DNA-binding domain HTH_12 PF08461.10 RLN72004.1 - 0.035 14.0 0.0 1.8 8.5 0.0 2.8 3 0 0 3 3 3 0 Ribonuclease R winged-helix domain DUF2491 PF10679.9 RLN72004.1 - 0.043 13.0 0.5 0.08 12.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) APG5 PF04106.12 RLN72005.1 - 4.9e-32 111.3 0.0 5.7e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 APG5 PF04106.12 RLN72006.1 - 9e-14 51.6 0.0 1.1e-13 51.4 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg5 U-box PF04564.15 RLN72007.1 - 4e-20 71.8 0.1 8.8e-20 70.7 0.1 1.5 1 0 0 1 1 1 1 U-box domain TPR_2 PF07719.17 RLN72007.1 - 4.3e-05 23.3 0.9 0.24 11.6 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN72007.1 - 0.0014 18.4 0.7 2.7 7.9 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat zf-NOSIP PF15906.5 RLN72007.1 - 0.0029 17.7 0.0 0.0066 16.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein TPR_12 PF13424.6 RLN72007.1 - 0.02 15.2 4.3 0.26 11.6 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-Nse PF11789.8 RLN72007.1 - 0.041 13.7 0.1 0.099 12.5 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TPR_16 PF13432.6 RLN72007.1 - 0.31 11.7 14.7 1.4 9.6 0.0 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Glyco_hydro_17 PF00332.18 RLN72008.1 - 0.00014 21.5 2.0 0.0028 17.3 0.5 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 SAPS PF04499.15 RLN72008.1 - 1.1 8.0 3.5 1.3 7.7 3.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DHC_N1 PF08385.12 RLN72009.1 - 1.5e-165 552.1 0.9 1.5e-165 552.1 0.9 4.5 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 RLN72009.1 - 2.9e-124 415.2 8.9 2.9e-124 415.2 8.9 3.8 3 1 1 4 4 4 1 Dynein heavy chain, N-terminal region 2 Importin_rep_6 PF18829.1 RLN72009.1 - 0.11 12.7 0.7 3.7 7.7 0.0 3.6 3 0 0 3 3 3 0 Importin repeat 6 MSA-2c PF12238.8 RLN72009.1 - 0.19 11.7 10.2 0.3 11.0 0.3 3.2 1 1 1 2 2 2 0 Merozoite surface antigen 2c DUF2786 PF10979.8 RLN72009.1 - 2.7 8.0 5.5 12 5.9 1.8 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) DUF4632 PF15451.6 RLN72010.1 - 0.28 11.3 0.9 7.7 6.7 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4632) tRNA-synt_2b PF00587.25 RLN72014.1 - 5.7e-30 104.6 0.0 1.7e-29 103.1 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 RLN72014.1 - 1.6e-13 50.6 0.0 6.3e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain RNA_GG_bind PF10258.9 RLN72015.1 - 3.3e-17 62.3 0.1 2.8e-16 59.3 0.1 2.4 1 1 0 1 1 1 1 PHAX RNA-binding domain bZIP_1 PF00170.21 RLN72016.1 - 0.00014 21.9 0.8 0.74 10.0 0.3 2.3 2 0 0 2 2 2 2 bZIP transcription factor GIT_CC PF16559.5 RLN72016.1 - 0.036 13.9 0.6 0.067 13.1 0.6 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor EzrA PF06160.12 RLN72016.1 - 0.069 11.3 1.1 0.093 10.9 1.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DZR PF12773.7 RLN72017.1 - 0.00042 20.3 0.5 0.00089 19.2 0.5 1.6 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 RLN72017.1 - 0.1 12.4 7.1 0.63 9.8 0.7 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.6 RLN72017.1 - 0.11 12.4 1.9 3.1 7.8 0.1 2.9 2 0 0 2 2 2 0 Nudix N-terminal RNA_POL_M_15KD PF02150.16 RLN72017.1 - 0.5 10.3 2.3 12 5.8 0.2 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-NADH-PPase PF09297.11 RLN72017.1 - 0.94 9.2 7.6 7.6 6.3 0.9 3.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.6 RLN72017.1 - 1.4 8.4 5.7 1.2 8.7 0.4 2.1 1 1 0 2 2 2 0 zinc-ribbon domain zf_UBZ PF18439.1 RLN72017.1 - 1.6 8.4 5.7 17 5.1 0.0 3.4 2 1 1 3 3 3 0 Ubiquitin-Binding Zinc Finger UPF0547 PF10571.9 RLN72017.1 - 2.4 8.3 5.1 7.8 6.7 0.3 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 HTH_Tnp_Tc5 PF03221.16 RLN72018.1 - 1e-11 44.7 0.0 2.7e-11 43.3 0.0 1.7 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.6 RLN72018.1 - 0.00019 21.1 0.1 0.00052 19.7 0.1 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_IclR PF09339.10 RLN72018.1 - 0.0002 21.1 0.3 0.00076 19.2 0.0 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_38 PF13936.6 RLN72018.1 - 0.0011 18.6 0.5 0.0023 17.6 0.5 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 RLN72018.1 - 0.0016 17.9 0.0 0.0053 16.3 0.0 1.9 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 RLN72018.1 - 0.0018 17.8 0.2 0.0048 16.4 0.2 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_11 PF08279.12 RLN72018.1 - 0.015 15.2 0.1 0.037 14.0 0.1 1.6 1 0 0 1 1 1 0 HTH domain CENP-B_N PF04218.13 RLN72018.1 - 0.031 13.9 0.1 0.078 12.6 0.1 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 RLN72018.1 - 0.032 14.3 0.1 0.085 13.0 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 RLN72018.1 - 0.039 13.8 0.0 0.039 13.8 0.0 3.3 3 1 1 4 4 4 0 AsnC-type helix-turn-helix domain HTH_5 PF01022.20 RLN72018.1 - 0.051 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_Mga PF08280.11 RLN72018.1 - 0.064 13.3 0.1 0.42 10.7 0.0 2.2 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_7 PF02796.15 RLN72018.1 - 0.2 11.7 1.7 0.91 9.7 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 RLN72018.1 - 4.9 7.8 6.1 7.6 7.2 0.1 3.3 3 0 0 3 3 3 0 Homeodomain-like domain Med18 PF09637.10 RLN72019.1 - 2.3e-05 24.3 0.0 2.7e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Med18 protein Ras PF00071.22 RLN72020.1 - 2.7e-36 124.6 0.1 4.2e-36 124.0 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN72020.1 - 1.6e-26 92.9 0.1 2.8e-26 92.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN72020.1 - 1.9e-14 53.5 0.4 4.3e-14 52.3 0.1 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.10 RLN72020.1 - 1.8e-05 24.3 0.0 3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 RLN72020.1 - 8.3e-05 22.0 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RLN72020.1 - 0.00013 22.0 0.0 0.00023 21.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 RLN72020.1 - 0.0099 15.1 0.0 0.059 12.5 0.0 2.0 2 0 0 2 2 2 1 G-protein alpha subunit AAA_16 PF13191.6 RLN72020.1 - 0.013 15.8 0.9 0.1 13.0 0.0 2.3 1 1 2 3 3 3 0 AAA ATPase domain ATP_bind_1 PF03029.17 RLN72020.1 - 0.043 13.6 0.1 0.13 12.1 0.0 1.8 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein TniB PF05621.11 RLN72020.1 - 0.047 13.1 0.0 0.21 11.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein ARID PF01388.21 RLN72021.1 - 1.6e-10 41.5 0.0 3.1e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 RLN72021.1 - 0.017 14.5 0.7 0.079 12.2 0.0 2.4 3 0 0 3 3 3 0 SWI/SNF-like complex subunit BAF250/Osa FAM176 PF14851.6 RLN72021.1 - 0.18 11.5 1.6 0.25 11.0 0.2 2.0 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.6 RLN72021.1 - 0.92 9.9 8.7 11 6.5 9.2 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.32 RLN72022.1 - 3.9e-30 103.4 3.5 2.8e-12 46.9 0.6 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Katanin_con80 PF13925.6 RLN72022.1 - 4.2e-26 91.9 0.0 6.7e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 con80 domain of Katanin ANAPC4_WD40 PF12894.7 RLN72022.1 - 1e-10 41.8 0.0 0.00011 22.4 0.0 3.6 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 RLN72022.1 - 0.00047 18.8 0.0 0.028 13.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 RLN72022.1 - 0.0026 17.6 0.0 0.023 14.6 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 RLN72022.1 - 0.0032 16.2 0.7 0.024 13.3 0.7 2.2 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RLN72022.1 - 0.009 15.0 0.1 0.22 10.5 0.1 2.7 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ROS_MUCR PF05443.11 RLN72022.1 - 0.024 14.7 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein Nucleoporin_N PF08801.11 RLN72022.1 - 0.046 12.5 0.0 7.8 5.1 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like CNOT1_CAF1_bind PF16415.5 RLN72023.1 - 1.2e-88 296.3 1.2 2e-88 295.5 1.2 1.3 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 RLN72023.1 - 3.2e-56 189.3 0.7 3.2e-56 189.3 0.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 RLN72023.1 - 1.5e-55 187.4 0.2 3.4e-55 186.2 0.2 1.5 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain Ebp2 PF05890.12 RLN72024.1 - 1.7e-57 195.0 19.3 2.2e-57 194.7 19.3 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 LRR_4 PF12799.7 RLN72025.1 - 3.1 8.3 4.5 4.7 7.8 0.1 3.3 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Glyco_hydro_32N PF00251.20 RLN72026.1 - 3.9e-42 144.9 4.0 6.8e-42 144.1 4.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 RLN72026.1 - 2.5e-24 86.1 0.3 4.1e-24 85.4 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.6 RLN72026.1 - 0.00029 20.2 0.2 0.00058 19.2 0.2 1.4 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 RLN72026.1 - 0.11 12.6 1.1 0.68 10.2 0.6 2.8 2 0 0 2 2 2 0 BNR/Asp-box repeat SWIM PF04434.17 RLN72027.1 - 0.0043 16.7 0.1 0.011 15.4 0.1 1.7 1 0 0 1 1 1 1 SWIM zinc finger NS3 PF17530.2 RLN72027.1 - 0.051 13.2 0.8 0.083 12.5 0.8 1.3 1 0 0 1 1 1 0 Non-structural protein NS3 DUF1381 PF07129.11 RLN72027.1 - 0.13 12.1 0.1 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1381) DHHC PF01529.20 RLN72028.1 - 9.3e-08 32.3 5.9 9.3e-08 32.3 5.9 3.1 2 2 1 3 3 3 1 DHHC palmitoyltransferase ABC_membrane PF00664.23 RLN72029.1 - 3.7e-47 161.3 6.9 2.9e-31 109.1 1.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN72029.1 - 6e-47 159.6 0.0 2.1e-26 93.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN72029.1 - 4e-12 46.6 0.0 0.0078 16.1 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 RLN72029.1 - 4e-07 30.4 0.1 0.054 13.8 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RLN72029.1 - 8.6e-07 29.7 0.0 0.0052 17.3 0.1 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 RLN72029.1 - 1.8e-06 28.0 0.0 0.024 14.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RLN72029.1 - 2e-06 27.9 0.0 0.026 14.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 RLN72029.1 - 1.1e-05 25.9 0.1 0.081 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 RLN72029.1 - 2e-05 24.1 0.0 0.0012 18.3 0.0 3.0 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RLN72029.1 - 3e-05 23.7 0.1 0.33 10.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 RLN72029.1 - 3.7e-05 23.9 0.0 0.059 13.4 0.0 2.6 2 0 0 2 2 2 2 Dynamin family cobW PF02492.19 RLN72029.1 - 4.6e-05 23.1 0.1 0.28 10.7 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 RLN72029.1 - 0.00032 19.8 0.1 0.23 10.5 0.0 2.7 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_33 PF13671.6 RLN72029.1 - 0.00067 19.8 0.0 0.72 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RLN72029.1 - 0.00094 19.0 0.0 0.078 12.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain Guanylate_kin PF00625.21 RLN72029.1 - 0.0053 16.5 0.0 0.072 12.8 0.0 2.2 2 0 0 2 2 2 1 Guanylate kinase FtsK_SpoIIIE PF01580.18 RLN72029.1 - 0.0064 15.9 0.1 0.99 8.7 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_7 PF12775.7 RLN72029.1 - 0.011 15.2 0.0 3.5 7.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 RLN72029.1 - 0.014 15.4 0.0 4.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 RLN72029.1 - 0.014 15.9 0.0 9.8 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 RLN72029.1 - 0.015 14.6 0.0 4.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 RLN72029.1 - 0.033 14.1 0.1 11 5.9 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 RLN72029.1 - 0.05 14.0 0.0 15 6.0 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 RLN72029.1 - 0.058 13.8 0.0 15 6.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Septin PF00735.18 RLN72029.1 - 0.061 12.6 0.0 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_25 PF13481.6 RLN72029.1 - 0.081 12.5 0.1 12 5.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 RLN72029.1 - 0.096 12.9 0.0 13 6.0 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 RLN72029.1 - 0.11 12.1 0.0 14 5.2 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 RLN72029.1 - 0.11 12.2 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 RLN72029.1 - 0.11 12.2 0.5 23 4.6 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein dNK PF01712.19 RLN72029.1 - 0.16 11.8 0.0 19 5.0 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase AFG1_ATPase PF03969.16 RLN72029.1 - 0.19 10.6 0.0 8.5 5.1 0.0 2.8 3 0 0 3 3 3 0 AFG1-like ATPase ATP_bind_1 PF03029.17 RLN72029.1 - 0.2 11.4 0.0 19 4.9 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein BT1 PF03092.16 RLN72030.1 - 5.2e-12 44.8 9.3 1.5e-09 36.7 2.3 2.4 2 0 0 2 2 2 2 BT1 family MFS_1_like PF12832.7 RLN72030.1 - 0.0013 17.6 7.0 0.0013 17.6 7.0 2.1 3 0 0 3 3 3 1 MFS_1 like family EF-hand_1 PF00036.32 RLN72032.1 - 3.5e-32 107.5 4.3 1.3e-06 27.5 0.0 6.6 6 0 0 6 6 6 6 EF hand EF-hand_7 PF13499.6 RLN72032.1 - 4.2e-29 100.8 12.1 3.8e-09 36.9 0.8 5.2 3 1 2 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.6 RLN72032.1 - 3.2e-27 92.1 5.2 4.2e-05 23.2 0.0 6.4 6 0 0 6 6 6 5 EF-hand domain EF-hand_5 PF13202.6 RLN72032.1 - 2.7e-25 86.7 4.7 1.2e-06 27.7 0.1 6.5 6 0 0 6 6 6 5 EF hand EF-hand_8 PF13833.6 RLN72032.1 - 2.3e-21 75.4 9.2 0.00051 19.8 0.3 6.4 5 1 1 6 6 6 5 EF-hand domain pair Caleosin PF05042.13 RLN72032.1 - 3e-05 24.0 0.1 2.5 8.0 0.0 4.4 2 2 2 4 4 4 2 Caleosin related protein EF-hand_9 PF14658.6 RLN72032.1 - 0.01 16.2 0.0 0.92 9.9 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain UcrQ PF02939.16 RLN72032.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 UcrQ family EF-hand_4 PF12763.7 RLN72032.1 - 0.16 11.9 0.3 3.7 7.5 0.1 3.0 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand COS PF18568.1 RLN72033.1 - 0.22 11.5 1.4 67 3.5 0.0 3.4 2 1 1 3 3 3 0 TRIM C-terminal subgroup One Signature domain HisKA PF00512.25 RLN72033.1 - 0.22 11.6 0.8 0.51 10.4 0.5 1.9 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain ABC2_membrane PF01061.24 RLN72034.1 - 4e-34 117.9 21.6 6.7e-34 117.1 21.6 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN72034.1 - 3.5e-24 85.9 0.0 5.6e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN72034.1 - 9.3e-09 35.5 0.0 0.0016 18.3 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN72034.1 - 0.00027 21.4 0.0 0.00055 20.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 RLN72034.1 - 0.0025 17.7 0.1 0.0049 16.8 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN72034.1 - 0.0053 16.5 0.1 0.013 15.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN72034.1 - 0.0084 15.7 0.0 0.052 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 RLN72034.1 - 0.021 15.4 0.0 0.034 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 RLN72034.1 - 0.19 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 RLN72034.1 - 0.2 11.1 0.2 6.3 6.2 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 RLN72034.1 - 4.1 6.4 20.9 9.7 5.2 20.9 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein BTB PF00651.31 RLN72035.1 - 4.1e-32 110.7 0.1 3.2e-14 53.1 0.0 3.6 2 1 1 3 3 3 2 BTB/POZ domain RCC1_2 PF13540.6 RLN72035.1 - 3.1e-05 23.6 8.2 0.012 15.4 0.3 3.0 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat BACK PF07707.15 RLN72035.1 - 0.031 14.4 1.5 0.057 13.5 0.4 2.0 2 0 0 2 2 2 0 BTB And C-terminal Kelch Stevor PF17410.2 RLN72035.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame RCC1 PF00415.18 RLN72035.1 - 3.2 8.5 12.8 2.6 8.8 4.8 3.9 3 1 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat Myticin-prepro PF10690.9 RLN72036.1 - 0.018 15.2 0.1 9.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel MGC-24 PF05283.11 RLN72036.1 - 0.28 11.7 7.9 0.62 10.5 7.9 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DBD_Tnp_Hermes PF10683.9 RLN72037.1 - 0.025 14.2 0.0 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain TFIIA PF03153.13 RLN72037.1 - 0.13 12.3 8.3 0.27 11.2 8.3 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Actin PF00022.19 RLN72038.1 - 1e-85 287.8 0.0 3.3e-84 282.9 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 RLN72038.1 - 0.0011 17.9 0.0 0.62 8.8 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein LUC7 PF03194.15 RLN72038.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 LUC7 N_terminus RNA_pol_Rpb4 PF03874.16 RLN72039.1 - 8.5e-15 55.2 2.1 2.3e-14 53.8 2.1 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb4 DEAD PF00270.29 RLN72040.1 - 1.7e-38 132.2 0.0 2.6e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN72040.1 - 1.9e-29 102.3 0.0 4.3e-29 101.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN72040.1 - 5.1e-06 26.6 0.0 1e-05 25.6 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RLN72040.1 - 1.1e-05 25.8 0.0 5.1e-05 23.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain DEAD PF00270.29 RLN72041.1 - 1.7e-38 132.2 0.0 2.6e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN72041.1 - 1.9e-29 102.3 0.0 4.3e-29 101.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN72041.1 - 5.1e-06 26.6 0.0 1e-05 25.6 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RLN72041.1 - 1.1e-05 25.8 0.0 5.1e-05 23.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain PhosphMutase PF10143.9 RLN72042.1 - 1.1e-44 152.3 0.0 1.8e-44 151.6 0.0 1.4 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 RLN72042.1 - 5.2e-23 81.7 0.0 7.1e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 RLN72042.1 - 1.2e-05 25.1 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Alk_phosphatase PF00245.20 RLN72042.1 - 0.011 14.7 0.3 0.016 14.2 0.3 1.1 1 0 0 1 1 1 0 Alkaline phosphatase V-SNARE_C PF12352.8 RLN72043.1 - 3.9e-06 27.0 0.2 7.3e-06 26.2 0.2 1.4 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Tim17 PF02466.19 RLN72043.1 - 0.0029 18.0 0.3 0.0039 17.6 0.2 1.3 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UvrD_C_2 PF13538.6 RLN72044.1 - 0.11 12.4 0.3 0.25 11.2 0.1 1.6 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain PhosphMutase PF10143.9 RLN72045.1 - 1e-44 152.4 0.0 1.6e-44 151.7 0.0 1.4 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 RLN72045.1 - 3e-28 98.8 0.0 4e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 RLN72045.1 - 1e-05 25.3 0.1 1.8e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Alk_phosphatase PF00245.20 RLN72045.1 - 0.014 14.4 0.4 0.02 13.9 0.4 1.1 1 0 0 1 1 1 0 Alkaline phosphatase Sulfatase PF00884.23 RLN72045.1 - 0.25 10.7 0.2 0.44 9.9 0.1 1.4 2 0 0 2 2 2 0 Sulfatase RRM_1 PF00076.22 RLN72046.1 - 7e-08 32.2 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RLN72046.1 - 0.038 13.9 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif ATP12 PF07542.11 RLN72047.1 - 5.2e-35 120.3 0.3 7.6e-35 119.8 0.3 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein SnoaL_2 PF12680.7 RLN72047.1 - 0.045 14.4 0.1 0.11 13.1 0.1 1.6 1 0 0 1 1 1 0 SnoaL-like domain RNA_pol_Rpb4 PF03874.16 RLN72048.1 - 8.5e-15 55.2 2.1 2.3e-14 53.8 2.1 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb4 RIIa PF02197.17 RLN72050.1 - 0.00062 19.4 1.4 0.0099 15.5 0.1 2.4 2 0 0 2 2 2 2 Regulatory subunit of type II PKA R-subunit Afi1 PF07792.12 RLN72051.1 - 0.031 14.7 0.0 0.057 13.9 0.0 1.6 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking VIR_N PF15912.5 RLN72051.1 - 0.059 13.0 12.1 0.094 12.3 12.1 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal DUF1682 PF07946.14 RLN72051.1 - 0.18 11.0 12.0 0.22 10.7 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Connexin PF00029.19 RLN72051.1 - 2.2 8.0 8.5 1.1 9.0 6.3 1.5 2 0 0 2 2 2 0 Connexin Presenilin PF01080.17 RLN72051.1 - 2.5 6.8 7.4 3.5 6.3 7.4 1.2 1 0 0 1 1 1 0 Presenilin DUF2828 PF11443.8 RLN72051.1 - 2.5 6.1 12.1 3.3 5.7 12.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Nucleo_P87 PF07267.11 RLN72051.1 - 2.7 6.8 11.0 3.1 6.5 11.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DNA_pol_phi PF04931.13 RLN72051.1 - 2.9 5.9 9.5 4.2 5.4 9.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi RPN2_C PF18004.1 RLN72051.1 - 4.4 7.2 10.4 7.9 6.4 10.4 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RR_TM4-6 PF06459.12 RLN72051.1 - 6.6 6.5 12.6 0.99 9.2 8.8 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF2828 PF11443.8 RLN72052.1 - 0.00057 18.1 1.8 0.0007 17.8 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) Di19_C PF14571.6 RLN72052.1 - 0.025 15.1 0.7 0.07 13.7 0.7 1.7 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal Conotoxin PF02950.17 RLN72052.1 - 0.22 12.6 1.0 0.77 10.8 1.0 2.0 1 0 0 1 1 1 0 Conotoxin U79_P34 PF03064.16 RLN72052.1 - 1.2 8.4 11.3 1.8 7.8 11.3 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DDRGK PF09756.9 RLN72052.1 - 1.8 8.1 16.6 2.9 7.4 16.6 1.3 1 0 0 1 1 1 0 DDRGK domain Presenilin PF01080.17 RLN72052.1 - 3.6 6.3 5.5 4.6 5.9 5.5 1.3 1 0 0 1 1 1 0 Presenilin DUF1676 PF07898.13 RLN72052.1 - 8.5 6.4 10.4 33 4.5 10.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) Glyco_hydro_3_C PF01915.22 RLN72053.1 - 6.4e-38 130.8 0.0 1.1e-37 129.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RLN72053.1 - 6.7e-13 48.6 0.2 1.9e-12 47.1 0.1 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain Cuticle_1 PF08140.11 RLN72053.1 - 0.1 12.6 0.0 0.43 10.7 0.0 2.1 1 0 0 1 1 1 0 Crustacean cuticle protein repeat CENP-L PF13092.6 RLN72054.1 - 1.2e-06 28.9 0.0 2.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 HEAT PF02985.22 RLN72055.1 - 0.021 15.1 10.6 0.32 11.4 0.0 5.2 4 0 0 4 4 4 0 HEAT repeat Arm PF00514.23 RLN72055.1 - 3.6 7.8 7.2 4.3 7.5 0.1 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Apolipoprotein PF01442.18 RLN72056.1 - 0.00024 21.0 16.2 0.007 16.3 16.2 2.2 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Taxilin PF09728.9 RLN72056.1 - 0.0045 16.2 2.4 0.0045 16.2 2.4 1.7 2 0 0 2 2 2 1 Myosin-like coiled-coil protein AAA_13 PF13166.6 RLN72056.1 - 0.0089 14.7 16.3 0.011 14.4 16.3 1.0 1 0 0 1 1 1 1 AAA domain UPF0184 PF03670.13 RLN72056.1 - 0.017 15.5 3.1 0.034 14.5 1.0 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) DUF3584 PF12128.8 RLN72056.1 - 0.019 12.5 12.5 0.024 12.2 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF842 PF05811.13 RLN72056.1 - 0.02 14.6 7.0 0.13 11.9 2.1 3.1 1 1 2 3 3 3 0 Eukaryotic protein of unknown function (DUF842) V-SNARE PF05008.15 RLN72056.1 - 0.026 14.9 1.7 0.026 14.9 1.7 3.0 2 2 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus ANAPC4 PF12896.7 RLN72056.1 - 0.13 11.7 1.4 2.1 7.8 0.4 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 ApoLp-III PF07464.11 RLN72056.1 - 0.14 12.2 25.4 0.078 13.1 4.7 3.4 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) APG17 PF04108.12 RLN72056.1 - 0.15 11.2 11.3 0.15 11.2 4.6 2.2 1 1 1 2 2 2 0 Autophagy protein Apg17 Spc7 PF08317.11 RLN72056.1 - 0.17 10.8 11.5 0.11 11.3 2.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein LMBR1 PF04791.16 RLN72056.1 - 0.28 10.1 5.9 0.4 9.5 5.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein ApoO PF09769.9 RLN72056.1 - 0.41 10.6 11.0 4.9 7.1 0.8 3.6 1 1 1 2 2 2 0 Apolipoprotein O SlyX PF04102.12 RLN72056.1 - 0.46 11.1 2.9 29 5.4 0.1 3.6 3 1 0 3 3 3 0 SlyX DUF885 PF05960.11 RLN72056.1 - 0.51 9.9 13.0 0.77 9.3 13.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Fib_alpha PF08702.10 RLN72056.1 - 0.55 10.4 7.4 1.2 9.3 2.4 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family GrpE PF01025.19 RLN72056.1 - 0.56 9.8 9.4 4.4 6.9 1.7 2.5 1 1 1 2 2 2 0 GrpE DUF883 PF05957.13 RLN72056.1 - 0.64 10.7 22.7 1.9 9.1 0.8 4.0 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF883) DUF4795 PF16043.5 RLN72056.1 - 1.5 8.4 7.5 2.3 7.8 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Baculo_PEP_C PF04513.12 RLN72056.1 - 1.6 8.8 15.8 0.81 9.7 1.3 2.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_Mu_Gam PF07352.12 RLN72056.1 - 1.8 8.5 13.5 4.9 7.0 0.9 3.6 2 1 2 4 4 4 0 Bacteriophage Mu Gam like protein Muted PF14942.6 RLN72056.1 - 2.2 8.6 8.1 15 5.9 0.2 2.9 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein Filament PF00038.21 RLN72056.1 - 4.4 6.8 12.4 1.3 8.5 1.5 2.4 1 1 1 2 2 2 0 Intermediate filament protein DrrA_P4M PF14860.6 RLN72056.1 - 4.4 7.2 9.5 1.3 9.0 3.6 2.5 2 1 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain DUF1451 PF07295.11 RLN72056.1 - 5.4 7.0 11.7 1.9 8.5 2.1 2.4 1 1 1 2 2 2 0 Zinc-ribbon containing domain DUF1690 PF07956.11 RLN72056.1 - 8.5 6.8 14.6 6 7.3 5.4 2.6 1 1 0 2 2 2 0 Protein of Unknown function (DUF1690) Apolipoprotein PF01442.18 RLN72057.1 - 1.8e-05 24.7 52.5 0.037 13.9 13.0 4.0 2 1 0 3 3 3 3 Apolipoprotein A1/A4/E domain LEA_4 PF02987.16 RLN72057.1 - 0.006 16.6 8.4 0.006 16.6 8.4 5.9 3 1 2 5 5 5 3 Late embryogenesis abundant protein YtxH PF12732.7 RLN72057.1 - 0.13 12.8 62.0 0.54 10.8 6.9 7.2 3 2 2 5 5 5 0 YtxH-like protein DUF883 PF05957.13 RLN72057.1 - 1.8 9.2 56.4 6.2 7.5 3.7 7.3 3 2 5 8 8 8 0 Bacterial protein of unknown function (DUF883) THDPS_N_2 PF14805.6 RLN72057.1 - 8.7 6.7 11.4 2.3 8.5 2.3 4.0 3 1 1 4 4 4 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal VHS PF00790.19 RLN72058.1 - 2.3e-25 89.1 0.0 4.1e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 RLN72058.1 - 3.4e-07 30.5 0.1 0.00029 21.1 0.0 2.5 2 0 0 2 2 2 2 GAT domain MAGI_u1 PF16663.5 RLN72058.1 - 0.0098 16.0 0.0 0.041 14.0 0.0 2.1 1 0 0 1 1 1 1 Unstructured region on MAGI malic PF00390.19 RLN72058.1 - 0.087 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, N-terminal domain Metallophos PF00149.28 RLN72060.1 - 7.8e-12 46.1 0.0 1.2e-11 45.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_8 PF13855.6 RLN72070.1 - 1.4e-12 47.1 8.8 3.1e-06 26.8 0.6 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RLN72070.1 - 2.8e-11 43.5 4.7 3.1e-06 27.4 0.6 3.6 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) zf-C3H1 PF10650.9 RLN72070.1 - 8e-08 31.9 4.5 1.7e-07 30.8 4.5 1.5 1 0 0 1 1 1 1 Putative zinc-finger domain NRDE-2 PF08424.10 RLN72070.1 - 1.5e-06 27.6 2.4 4.6e-06 26.0 2.4 1.8 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference LRR_9 PF14580.6 RLN72070.1 - 0.0038 16.7 0.3 0.01 15.3 0.3 1.7 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 RLN72070.1 - 0.0078 16.6 2.0 40 5.3 0.0 5.4 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 RLN72070.1 - 4.1 7.7 5.3 1.3e+02 3.0 0.2 4.5 4 0 0 4 4 4 0 Leucine Rich repeat PAP2 PF01569.21 RLN72072.1 - 3.6e-13 49.4 0.7 5.1e-13 49.0 0.0 1.5 2 0 0 2 2 2 1 PAP2 superfamily zf-CCCH_4 PF18044.1 RLN72073.1 - 1.8e-14 53.1 40.1 1.8e-08 34.0 3.3 3.9 4 0 0 4 4 4 3 CCCH-type zinc finger zf_CCCH_4 PF18345.1 RLN72073.1 - 1.6e-12 47.0 32.1 2.1e-06 27.6 6.2 3.9 3 1 0 3 3 3 3 Zinc finger domain zf-CCCH PF00642.24 RLN72073.1 - 4.8e-09 35.9 28.4 1.7e-05 24.6 1.9 3.8 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 RLN72073.1 - 5.2e-09 36.8 15.5 2.9e-05 24.7 0.6 3.7 3 1 1 4 4 4 3 Torus domain zf-CCCH_3 PF15663.5 RLN72073.1 - 0.0024 18.1 9.2 0.039 14.2 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 RLN72073.1 - 0.0063 16.9 1.9 0.0063 16.9 1.9 3.7 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger LRR_8 PF13855.6 RLN72074.1 - 4.2e-30 103.3 31.9 3.6e-09 36.3 0.2 3.5 1 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 RLN72074.1 - 7.6e-14 51.6 13.8 0.0012 19.2 0.0 5.2 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN72074.1 - 1.3e-05 25.1 8.9 11 7.1 0.0 7.4 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.6 RLN72074.1 - 0.071 13.2 15.1 15 6.0 0.4 7.2 8 1 0 8 8 8 0 Leucine Rich repeat Corona_5a PF06336.11 RLN72074.1 - 0.2 11.7 0.5 0.55 10.2 0.5 1.7 1 0 0 1 1 1 0 Coronavirus 5a protein Kelch_4 PF13418.6 RLN72075.1 - 6.3e-16 58.1 0.3 1.8e-05 24.6 0.0 4.0 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_3 PF13415.6 RLN72075.1 - 2.3e-12 46.8 0.6 0.00022 21.4 0.0 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 RLN72075.1 - 1.1e-09 37.7 0.1 0.0014 18.2 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 RLN72075.1 - 4.7e-09 36.2 0.6 0.0058 16.9 0.0 4.0 3 1 1 4 4 4 2 Kelch motif fn3 PF00041.21 RLN72075.1 - 3.3e-07 30.5 0.1 1.8e-06 28.2 0.1 2.3 1 0 0 1 1 1 1 Fibronectin type III domain Kelch_5 PF13854.6 RLN72075.1 - 4.6e-07 29.7 1.9 0.3 11.1 0.2 3.6 3 0 0 3 3 3 2 Kelch motif zf-C3HC4_2 PF13923.6 RLN72075.1 - 2.8e-06 27.1 8.0 6.2e-06 26.0 8.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Kelch_2 PF07646.15 RLN72075.1 - 5.3e-06 26.2 0.5 0.038 14.0 0.0 3.7 3 0 0 3 3 3 2 Kelch motif zf-RING_2 PF13639.6 RLN72075.1 - 5.1e-05 23.5 7.7 0.00015 22.0 7.7 1.9 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 RLN72075.1 - 5.7e-05 22.9 7.7 0.00015 21.6 7.7 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 RLN72075.1 - 7.6e-05 22.5 6.7 0.0002 21.2 6.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN72075.1 - 0.0001 22.1 7.0 0.0002 21.1 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Anoctamin PF04547.12 RLN72075.1 - 0.0014 17.5 0.1 0.0019 17.1 0.1 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel zf-RING_UBOX PF13445.6 RLN72075.1 - 0.0045 17.0 8.0 0.012 15.7 8.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 RLN72075.1 - 0.0054 16.8 3.2 0.013 15.6 3.2 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 RLN72075.1 - 0.0059 16.7 9.3 0.017 15.3 9.3 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 RLN72075.1 - 0.0088 16.0 5.9 0.029 14.3 5.9 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-Sec23_Sec24 PF04810.15 RLN72075.1 - 0.01 15.9 2.0 0.79 9.8 0.0 2.4 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger TSP_1 PF00090.19 RLN72075.1 - 0.015 15.5 5.6 0.035 14.3 5.6 1.7 1 0 0 1 1 1 0 Thrombospondin type 1 domain zf-rbx1 PF12678.7 RLN72075.1 - 10 6.5 10.3 1.2 9.5 4.5 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain Myosin_head PF00063.21 RLN72077.1 - 3.7e-202 673.2 0.0 5.3e-202 672.7 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 RLN72077.1 - 5e-06 25.8 30.3 0.075 12.9 0.1 5.8 5 0 0 5 5 5 5 IQ calmodulin-binding motif AAA_16 PF13191.6 RLN72077.1 - 0.055 13.8 0.0 0.055 13.8 0.0 3.0 3 1 0 3 3 2 0 AAA ATPase domain AAA_22 PF13401.6 RLN72077.1 - 0.093 13.0 2.4 0.22 11.8 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RLN72077.1 - 0.11 13.0 0.5 0.74 10.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain Glyco_hydro_4 PF02056.16 RLN72077.1 - 0.18 11.3 0.1 0.45 10.0 0.1 1.6 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase ZapB PF06005.12 RLN72077.1 - 0.51 10.8 29.9 1.3 9.5 2.7 5.0 3 1 1 4 4 4 0 Cell division protein ZapB HALZ PF02183.18 RLN72077.1 - 0.94 9.8 14.2 13 6.1 0.2 4.9 4 0 0 4 4 4 0 Homeobox associated leucine zipper UPF0184 PF03670.13 RLN72077.1 - 1.2 9.5 6.3 1.2 9.5 0.4 2.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Lzipper-MIP1 PF14389.6 RLN72077.1 - 2.8 8.3 19.3 0.16 12.3 4.4 3.5 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 bZIP_1 PF00170.21 RLN72077.1 - 6.4 7.0 17.4 0.79 9.9 0.2 4.3 4 0 0 4 4 4 0 bZIP transcription factor CactinC_cactus PF09732.9 RLN72078.1 - 7.5e-60 200.4 9.9 9.7e-60 200.0 9.9 1.1 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 RLN72078.1 - 1.6e-05 24.7 0.6 2.3e-05 24.2 0.0 1.5 2 0 0 2 2 2 1 Conserved mid region of cactin Pkinase PF00069.25 RLN72080.1 - 4.9e-49 167.1 0.0 8.4e-49 166.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN72080.1 - 1e-44 152.8 0.0 1.6e-44 152.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TMEM154 PF15102.6 RLN72080.1 - 0.002 18.0 0.0 0.0047 16.8 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF1180 PF06679.12 RLN72080.1 - 0.0032 17.9 0.1 0.0061 17.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) TMEM51 PF15345.6 RLN72080.1 - 0.0058 16.5 0.4 0.0091 15.9 0.4 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 EphA2_TM PF14575.6 RLN72080.1 - 0.0098 16.8 0.0 0.023 15.6 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 RLN72080.1 - 0.014 15.7 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Cytomega_TRL10 PF06084.11 RLN72080.1 - 0.022 14.8 0.1 0.053 13.5 0.1 1.6 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein DUF5305 PF17231.2 RLN72080.1 - 0.028 13.8 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) VMA21 PF09446.10 RLN72080.1 - 0.033 14.3 0.7 0.12 12.5 0.7 1.9 1 0 0 1 1 1 0 VMA21-like domain CD34_antigen PF06365.12 RLN72080.1 - 0.045 13.3 0.1 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 CD34/Podocalyxin family RIFIN PF02009.16 RLN72080.1 - 0.073 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Rifin Haspin_kinase PF12330.8 RLN72080.1 - 0.088 11.7 0.0 0.17 10.8 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain SKG6 PF08693.10 RLN72080.1 - 0.18 11.2 1.6 0.48 9.9 1.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MiAMP1 PF09117.10 RLN72080.1 - 0.21 11.8 5.4 4.4 7.6 1.2 2.8 1 1 1 2 2 2 0 MiAMP1 SpoIIIAH PF12685.7 RLN72080.1 - 5.2 6.8 8.4 67 3.2 8.4 2.1 1 1 0 1 1 1 0 SpoIIIAH-like protein Pkinase PF00069.25 RLN72081.1 - 1.7e-49 168.6 0.0 2.7e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN72081.1 - 8.5e-44 149.8 0.0 1.1e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3430 PF11912.8 RLN72081.1 - 0.0018 18.3 3.3 0.0018 18.3 3.3 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3430) Haspin_kinase PF12330.8 RLN72081.1 - 0.047 12.6 0.0 0.071 12.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF4841 PF16129.5 RLN72081.1 - 0.14 12.4 0.5 11 6.3 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4841) Sec3_C PF09763.9 RLN72085.1 - 0.013 13.9 2.1 0.021 13.2 2.1 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 Codanin-1_C PF15296.6 RLN72085.1 - 0.018 15.1 0.4 0.16 12.0 0.0 2.8 2 0 0 2 2 2 0 Codanin-1 C-terminus Glucan_synthase PF02364.15 RLN72086.1 - 1.1e-185 619.2 22.3 1.7e-167 559.1 9.6 2.6 2 1 1 3 3 3 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 RLN72086.1 - 2.5e-24 86.0 3.1 2.5e-23 82.8 3.1 2.6 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Sugar_tr PF00083.24 RLN72086.1 - 1.8e-18 66.7 20.4 1.8e-18 66.7 20.4 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN72086.1 - 3e-11 42.9 27.2 3e-11 42.9 27.2 5.1 3 2 1 5 5 5 1 Major Facilitator Superfamily DUF4778 PF16008.5 RLN72087.1 - 2 8.4 8.6 2.8 7.9 8.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) SWIRM-assoc_2 PF16496.5 RLN72087.1 - 5.5 5.8 9.9 7.1 5.4 9.9 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Ysc84 PF04366.12 RLN72088.1 - 4.6e-34 116.9 0.2 9.4e-34 115.9 0.2 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator zf-ribbon_3 PF13248.6 RLN72088.1 - 0.0065 15.8 1.7 0.0065 15.8 1.7 2.1 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.7 RLN72088.1 - 0.022 14.8 0.7 0.022 14.8 0.7 3.8 3 1 0 3 3 3 0 Double zinc ribbon VIR_N PF15912.5 RLN72088.1 - 0.038 13.6 3.1 0.07 12.7 3.1 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal zinc_ribbon_2 PF13240.6 RLN72088.1 - 0.27 11.0 7.7 5.4 6.9 7.7 2.8 1 1 0 1 1 1 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 RLN72088.1 - 2.4 7.9 10.1 7 6.4 0.6 3.6 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Mito_fiss_reg PF05308.11 RLN72088.1 - 8.1 6.5 7.2 24 4.9 7.3 1.8 1 1 0 1 1 1 0 Mitochondrial fission regulator AAA_2 PF07724.14 RLN72089.1 - 5.6e-51 173.1 0.1 2.2e-47 161.3 0.0 3.1 3 1 1 4 4 3 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 RLN72089.1 - 5e-34 116.3 3.1 5e-34 116.3 3.1 2.9 1 1 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 RLN72089.1 - 5.8e-25 87.2 0.1 1.9e-24 85.5 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 RLN72089.1 - 1.6e-22 80.4 0.6 1e-13 51.9 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RLN72089.1 - 1.7e-17 63.7 0.4 7.6e-12 45.4 0.0 3.5 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RLN72089.1 - 3.1e-07 31.0 10.3 0.0005 20.5 0.1 4.8 5 1 1 6 6 4 2 AAA ATPase domain Sigma54_activat PF00158.26 RLN72089.1 - 3.8e-07 30.0 0.0 0.0017 18.1 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 RLN72089.1 - 8.2e-07 28.6 0.2 0.068 12.6 0.0 3.5 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 RLN72089.1 - 1.5e-06 28.5 6.4 0.004 17.4 0.0 4.9 2 2 2 4 4 4 2 AAA domain IstB_IS21 PF01695.17 RLN72089.1 - 1.8e-05 24.5 0.0 0.055 13.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.6 RLN72089.1 - 6.4e-05 22.6 3.8 0.00064 19.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 RLN72089.1 - 0.00025 20.6 0.0 0.35 10.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 RLN72089.1 - 0.00028 21.4 6.8 0.41 11.2 0.0 3.9 3 2 1 4 4 3 2 AAA domain RNA_helicase PF00910.22 RLN72089.1 - 0.0003 21.1 0.0 1.7 9.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.12 RLN72089.1 - 0.00032 20.5 4.0 2.1 8.1 0.0 4.0 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 RLN72089.1 - 0.00036 20.3 0.0 0.54 10.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 RLN72089.1 - 0.00074 19.5 0.0 0.063 13.2 0.0 2.9 3 0 0 3 3 2 1 NACHT domain RsgA_GTPase PF03193.16 RLN72089.1 - 0.00095 19.1 0.0 1.4 8.8 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase TsaE PF02367.17 RLN72089.1 - 0.0011 18.9 0.6 1.8 8.6 0.0 2.9 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 RLN72089.1 - 0.0012 19.4 10.5 6.2 7.3 11.1 3.3 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 RLN72089.1 - 0.0013 19.0 0.0 1.7 8.9 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TIP49 PF06068.13 RLN72089.1 - 0.002 17.4 0.3 0.91 8.7 0.0 2.6 3 0 0 3 3 3 1 TIP49 P-loop domain AAA_33 PF13671.6 RLN72089.1 - 0.0028 17.8 0.0 4.7 7.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RLN72089.1 - 0.0098 16.2 1.4 2 8.8 1.0 3.5 3 1 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 RLN72089.1 - 0.014 15.3 9.0 2.9 7.7 0.0 4.8 4 2 0 5 5 4 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 RLN72089.1 - 0.02 15.1 3.1 11 6.3 0.0 4.0 3 1 2 5 5 5 0 AAA domain PduV-EutP PF10662.9 RLN72089.1 - 0.021 14.6 0.0 0.72 9.6 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_3 PF07726.11 RLN72089.1 - 0.022 14.6 0.1 15 5.5 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 RLN72089.1 - 0.031 14.1 0.0 14 5.4 0.0 3.5 3 0 0 3 3 3 0 DNA polymerase III, delta subunit ABC_tran PF00005.27 RLN72089.1 - 0.034 14.7 1.9 6.5 7.3 0.0 3.6 3 1 0 3 3 3 0 ABC transporter SRP54 PF00448.22 RLN72089.1 - 0.092 12.4 3.3 4.3 6.9 0.0 3.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 RLN72089.1 - 0.12 12.2 0.0 2.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Torsin PF06309.11 RLN72089.1 - 0.17 12.0 0.0 0.69 10.0 0.0 1.9 2 0 0 2 2 2 0 Torsin V_ATPase_I PF01496.19 RLN72089.1 - 0.39 8.6 3.8 0.5 8.2 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 RLN72089.1 - 1.9 7.8 8.0 3.1 7.1 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) 4HB_MCP_1 PF12729.7 RLN72089.1 - 3 7.3 6.4 7.3 6.1 6.4 1.6 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF848 PF05852.11 RLN72089.1 - 4.7 7.3 10.4 3.5 7.7 6.9 2.3 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) MatE PF01554.18 RLN72090.1 - 7.4e-14 51.7 2.2 7.4e-14 51.7 2.2 1.6 2 0 0 2 2 2 1 MatE Polysacc_synt_C PF14667.6 RLN72090.1 - 0.0041 17.2 2.1 0.0041 17.2 2.1 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis C-terminal domain YcaO PF02624.16 RLN72093.1 - 0.14 11.4 4.7 0.081 12.2 1.3 1.9 1 1 1 2 2 2 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding Ribonuclease_T2 PF00445.18 RLN72095.1 - 3.6e-18 66.4 0.0 5.2e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Glucosamine_iso PF01182.20 RLN72096.1 - 9e-22 78.0 0.0 1.1e-21 77.8 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Peptidase_M3 PF01432.20 RLN72097.1 - 5.6e-76 256.6 0.6 9.2e-76 255.9 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M3 Glucosamine_iso PF01182.20 RLN72097.1 - 2.4e-24 86.5 0.2 1.4e-19 70.8 0.0 2.6 2 0 0 2 2 2 2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Spectrin PF00435.21 RLN72097.1 - 0.39 11.2 4.7 11 6.5 0.1 2.5 2 0 0 2 2 2 0 Spectrin repeat Peptidase_M50B PF13398.6 RLN72097.1 - 0.49 10.0 3.0 0.53 9.9 0.3 2.1 2 0 0 2 2 2 0 Peptidase M50B-like STT3 PF02516.14 RLN72100.1 - 6.1e-94 315.7 29.7 1.6e-88 297.8 24.7 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Pkinase_Tyr PF07714.17 RLN72101.1 - 5.5e-49 166.8 0.0 6.7e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN72101.1 - 2.9e-48 164.6 0.0 3.9e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 RLN72101.1 - 0.17 11.8 0.0 0.6 10.0 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN72101.1 - 0.19 10.7 0.0 0.38 9.6 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain DNA_ligase_A_M PF01068.21 RLN72102.1 - 3.5e-30 105.2 0.0 1.1e-29 103.5 0.0 1.8 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 RLN72102.1 - 3e-25 88.7 0.1 9.2e-25 87.1 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_A_N PF04675.14 RLN72102.1 - 3.7e-16 59.9 0.1 6.6e-16 59.1 0.1 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_OB_2 PF14743.6 RLN72102.1 - 0.0045 17.0 2.1 0.32 11.1 0.2 2.7 2 0 0 2 2 2 2 DNA ligase OB-like domain Med13_N PF11597.8 RLN72102.1 - 0.085 12.2 0.1 0.3 10.4 0.0 1.9 2 0 0 2 2 2 0 Mediator complex subunit 13 N-terminal FYVE PF01363.21 RLN72104.1 - 3.9e-14 52.5 14.4 8e-14 51.5 14.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 RLN72104.1 - 7.5e-07 29.8 0.1 1.9e-06 28.5 0.1 1.7 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 RLN72104.1 - 2e-06 28.2 0.0 4e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 GAF domain SpoVT_C PF15714.5 RLN72104.1 - 0.0055 16.8 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Stage V sporulation protein T C-terminal, transcription factor MlaD PF02470.20 RLN72104.1 - 0.013 15.8 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 MlaD protein FYVE_2 PF02318.16 RLN72104.1 - 0.97 9.7 8.3 2.8 8.2 8.3 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger DFRP_C PF16543.5 RLN72105.1 - 2.5e-21 75.9 1.1 2.5e-21 75.9 1.1 2.4 2 1 0 2 2 2 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 RLN72105.1 - 4.4e-07 30.6 8.3 5.9e-05 23.7 3.7 3.6 3 1 0 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 RLN72105.1 - 1.1e-05 25.3 4.2 1.1e-05 25.3 4.2 2.9 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 RLN72105.1 - 3.2e-05 23.7 1.4 3.2e-05 23.7 1.4 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 RLN72105.1 - 0.00012 21.8 8.1 0.00065 19.4 1.4 3.1 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 RLN72105.1 - 0.019 15.2 2.2 0.18 12.0 0.1 2.5 1 1 1 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 RLN72105.1 - 0.026 15.0 7.0 0.05 14.1 1.7 2.6 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Ribosomal_60s PF00428.19 RLN72105.1 - 0.032 14.8 2.1 0.032 14.8 2.1 4.4 3 2 2 5 5 5 0 60s Acidic ribosomal protein CAP_GLY PF01302.25 RLN72110.1 - 9.3e-20 70.4 0.1 1.7e-19 69.6 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain DnaJ PF00226.31 RLN72110.1 - 9.6e-18 64.1 0.2 1.6e-17 63.4 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 RLN72110.1 - 0.11 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein CENP-B_dimeris PF09026.10 RLN72110.1 - 0.15 12.5 4.8 3.4 8.1 0.5 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain ABC2_membrane PF01061.24 RLN72111.1 - 8.4e-39 133.2 21.3 8.4e-39 133.2 21.3 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RLN72111.1 - 4e-14 53.3 0.0 6.3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 RLN72111.1 - 7.6e-07 28.6 13.4 7.6e-07 28.6 13.4 1.9 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 RLN72111.1 - 0.001 19.0 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_2 PF12679.7 RLN72111.1 - 0.0015 17.9 8.3 0.03 13.6 7.5 2.2 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 RLN72111.1 - 0.049 13.4 0.4 0.11 12.3 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN72111.1 - 0.13 12.7 0.3 0.24 11.9 0.3 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RLN72111.1 - 0.15 12.6 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RLN72111.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pur_ac_phosph_N PF16656.5 RLN72116.1 - 1.8e-12 47.6 3.7 6.7e-12 45.8 0.2 2.6 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain tRNA-synt_1e PF01406.19 RLN72117.1 - 2.1e-13 50.3 0.1 2.5e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain FCH PF00611.23 RLN72122.1 - 2.6e-13 50.1 1.9 1.1e-08 35.2 0.4 3.1 3 0 0 3 3 3 2 Fes/CIP4, and EFC/F-BAR homology domain PSII_Pbs27 PF13326.6 RLN72122.1 - 0.085 13.2 2.1 3.3 8.0 0.0 3.2 3 0 0 3 3 3 0 Photosystem II Pbs27 POX PF07526.11 RLN72122.1 - 0.59 10.7 4.3 0.59 10.7 1.0 2.6 2 1 0 2 2 2 0 Associated with HOX Tail_P2_I PF09684.10 RLN72124.1 - 0.017 15.1 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Phage tail protein (Tail_P2_I) DUF2098 PF09871.9 RLN72124.1 - 0.064 13.6 0.6 0.064 13.6 0.6 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) RRM_1 PF00076.22 RLN72125.1 - 0.00019 21.2 0.0 0.00037 20.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HalX PF08663.10 RLN72125.1 - 0.014 15.7 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 HalX domain Sel1 PF08238.12 RLN72126.1 - 1.8e-11 44.3 20.0 0.0014 19.2 0.1 6.3 5 1 0 5 5 5 4 Sel1 repeat Pkinase_Tyr PF07714.17 RLN72127.1 - 4.1e-35 121.3 0.0 2.3e-34 118.9 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RLN72127.1 - 4e-29 101.8 0.0 1.3e-27 96.8 0.0 2.7 2 2 1 3 3 3 1 Protein kinase domain RIO1 PF01163.22 RLN72127.1 - 0.0064 16.1 0.6 0.019 14.6 0.0 2.1 2 1 0 2 2 2 1 RIO1 family APH PF01636.23 RLN72127.1 - 0.019 14.9 1.4 0.25 11.2 0.0 3.0 3 1 1 4 4 4 0 Phosphotransferase enzyme family Spec3 PF15795.5 RLN72127.1 - 0.23 12.0 0.1 0.48 11.0 0.1 1.5 1 0 0 1 1 1 0 Ectodermal ciliogenesis protein Antigen_Bd37 PF11641.8 RLN72127.1 - 0.9 9.0 5.4 0.31 10.5 0.3 2.1 1 1 0 2 2 2 0 Glycosylphosphatidylinositol-anchored merozoite surface protein Pkinase_Tyr PF07714.17 RLN72128.1 - 4.7e-42 144.1 0.0 6e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN72128.1 - 4.1e-37 128.0 0.0 5.6e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DZR PF12773.7 RLN72128.1 - 0.00026 21.0 0.5 0.00072 19.5 0.5 1.7 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 RLN72128.1 - 0.00037 21.2 0.5 0.00084 20.0 0.5 1.6 1 0 0 1 1 1 1 zinc-ribbon family APH PF01636.23 RLN72128.1 - 0.0063 16.5 0.0 0.0095 15.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family UPF0547 PF10571.9 RLN72128.1 - 0.0077 16.3 4.1 0.018 15.1 4.1 1.6 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.6 RLN72128.1 - 0.018 14.7 2.0 0.018 14.7 2.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 RLN72128.1 - 0.038 13.7 3.5 2.8 7.7 0.1 2.7 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain RIO1 PF01163.22 RLN72128.1 - 0.051 13.2 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 RLN72128.1 - 0.066 12.5 0.0 0.085 12.2 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 RLN72128.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_POL_M_15KD PF02150.16 RLN72128.1 - 3 7.8 9.3 2.1 8.3 0.2 3.4 4 0 0 4 4 4 0 RNA polymerases M/15 Kd subunit zf-ribbon_3 PF13248.6 RLN72128.1 - 9.8 5.7 10.2 4.6 6.8 4.9 2.9 2 1 1 3 3 3 0 zinc-ribbon domain Ph1570 PF09638.10 RLN72129.1 - 0.18 11.6 0.2 19 5.1 0.0 2.3 2 0 0 2 2 2 0 Ph1570 protein DUF1678 PF07913.11 RLN72129.1 - 0.4 10.4 2.6 1 9.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1678) Cortex-I_coil PF09304.10 RLN72129.1 - 2.4 8.4 13.6 0.26 11.5 0.9 3.1 1 1 2 3 3 3 0 Cortexillin I, coiled coil HEPN_STY4199 PF18729.1 RLN72137.1 - 0.062 12.5 0.9 0.64 9.2 0.0 2.1 2 0 0 2 2 2 0 STY4199-like HEPN DUF4539 PF15072.6 RLN72138.1 - 1.8e-22 79.1 0.0 4e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) NuA4 PF09340.10 RLN72138.1 - 0.00025 20.9 0.0 0.00076 19.3 0.0 1.9 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 bPH_1 PF08000.11 RLN72139.1 - 0.048 13.8 0.9 11 6.1 0.1 2.4 2 0 0 2 2 2 0 Bacterial PH domain GAS PF13851.6 RLN72139.1 - 1.7 7.9 34.7 1.1 8.6 17.8 2.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.19 RLN72139.1 - 6.1 4.6 15.1 8.9 4.1 15.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Arm PF00514.23 RLN72141.1 - 9.2e-20 70.0 21.3 0.12 12.4 0.0 11.0 10 1 1 11 11 11 6 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN72141.1 - 2.1e-11 43.0 10.7 14 6.3 0.0 9.7 10 0 0 10 10 10 0 HEAT repeat HEAT_EZ PF13513.6 RLN72141.1 - 2.3e-11 43.9 24.8 0.0082 16.6 0.1 7.4 5 1 3 8 8 8 6 HEAT-like repeat OpuAC PF04069.12 RLN72141.1 - 2.5e-05 24.0 0.0 6.7 6.2 0.0 4.0 4 0 0 4 4 4 2 Substrate binding domain of ABC-type glycine betaine transport system Tex_N PF09371.10 RLN72141.1 - 0.0012 18.6 1.6 33 4.1 0.0 4.6 5 0 0 5 5 5 0 Tex-like protein N-terminal domain Uso1_p115_head PF04869.14 RLN72141.1 - 0.012 14.7 0.0 15 4.6 0.0 3.2 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, head region FA_FANCE PF11510.8 RLN72141.1 - 0.022 14.1 2.5 18 4.6 0.0 3.6 4 0 0 4 4 4 0 Fanconi Anaemia group E protein FANCE AbiJ_NTD5 PF18865.1 RLN72141.1 - 0.031 14.1 0.5 95 2.9 0.0 4.1 4 0 0 4 4 4 0 AbiJ N-terminal domain 5 NCD1 PF04904.13 RLN72141.1 - 0.052 13.5 0.2 2.1e+02 2.0 0.0 4.8 5 0 0 5 5 5 0 NAB conserved region 1 (NCD1) HEAT_2 PF13646.6 RLN72141.1 - 0.077 13.4 33.5 0.063 13.7 3.6 5.6 2 1 7 9 9 9 0 HEAT repeats HTH_ParB PF17762.1 RLN72141.1 - 0.083 12.7 0.3 1e+02 2.8 0.0 3.8 3 0 0 3 3 3 0 HTH domain found in ParB protein NFACT-C PF11923.8 RLN72141.1 - 0.28 11.1 1.8 37 4.3 0.1 3.1 3 0 0 3 3 3 0 NFACT protein C-terminal domain Phasin_2 PF09361.10 RLN72141.1 - 0.94 9.8 4.0 44 4.4 0.1 3.3 3 0 0 3 3 3 0 Phasin protein UBX PF00789.20 RLN72144.1 - 3.4e-15 56.0 0.0 5.7e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 RLN72144.1 - 4e-15 55.8 0.1 7.6e-15 54.9 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like UIM PF02809.20 RLN72144.1 - 5.8e-05 22.7 3.5 0.0002 21.1 3.5 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF5399 PF17377.2 RLN72144.1 - 0.066 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5399) ABC_tran PF00005.27 RLN72145.1 - 9.6e-10 39.1 0.0 9.6e-10 39.1 0.0 2.3 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 RLN72145.1 - 0.04 13.7 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 RLN72145.1 - 0.14 11.5 25.0 0.46 9.9 25.0 1.8 1 1 0 1 1 1 0 ABC-2 type transporter DUF3099 PF11298.8 RLN72147.1 - 0.24 11.6 0.1 0.24 11.6 0.1 3.8 4 1 1 5 5 5 0 Protein of unknown function (DUF3099) PX PF00787.24 RLN72152.1 - 7.4e-06 25.9 0.2 1.6e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 PX domain IRK_C PF17655.1 RLN72153.1 - 6.7e-23 81.2 0.0 5e-11 42.5 0.0 2.2 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 RLN72153.1 - 1.6e-14 53.9 3.6 3.7e-12 46.3 3.6 2.3 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 RLN72153.1 - 0.00065 19.6 8.4 0.0013 18.6 8.4 1.5 1 0 0 1 1 1 1 Ion channel Saf_2TM PF18303.1 RLN72153.1 - 0.38 10.3 2.5 0.37 10.4 1.1 1.6 1 1 0 1 1 1 0 SAVED-fused 2TM effector domain CAP_GLY PF01302.25 RLN72154.1 - 6.4e-21 74.1 0.2 1.2e-20 73.3 0.2 1.5 1 0 0 1 1 1 1 CAP-Gly domain GAS PF13851.6 RLN72154.1 - 0.0066 15.8 9.5 0.0074 15.7 8.4 1.5 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Macoilin PF09726.9 RLN72154.1 - 0.012 14.2 6.6 0.018 13.7 6.6 1.2 1 0 0 1 1 1 0 Macoilin family MPS2 PF17060.5 RLN72154.1 - 0.013 14.8 1.3 0.021 14.1 1.3 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 Tropomyosin_1 PF12718.7 RLN72154.1 - 0.027 14.6 11.0 0.049 13.8 11.0 1.3 1 0 0 1 1 1 0 Tropomyosin like FAM76 PF16046.5 RLN72154.1 - 0.075 12.4 6.9 0.14 11.5 0.9 2.1 1 1 1 2 2 2 0 FAM76 protein Lebercilin PF15619.6 RLN72154.1 - 0.26 10.9 12.3 0.48 10.1 12.3 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease WHEP-TRS PF00458.20 RLN72154.1 - 0.3 11.3 2.4 0.79 9.9 2.4 1.8 1 0 0 1 1 1 0 WHEP-TRS domain Csm1_N PF18504.1 RLN72154.1 - 0.4 11.0 6.8 2.6 8.5 1.5 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF4407 PF14362.6 RLN72154.1 - 0.53 9.6 5.4 0.78 9.0 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 RLN72154.1 - 1 9.8 3.0 7.3 7.1 0.3 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 RLN72154.1 - 1.3 9.3 12.1 0.27 11.5 1.6 3.2 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding FAM184 PF15665.5 RLN72154.1 - 2.3 8.0 14.1 5.1 6.8 14.1 1.5 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B TMF_DNA_bd PF12329.8 RLN72154.1 - 2.9 8.0 9.6 12 6.0 1.9 2.7 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding bZIP_2 PF07716.15 RLN72154.1 - 6.4 6.9 9.3 1.4 9.1 1.5 3.2 3 0 0 3 3 3 0 Basic region leucine zipper TIM PF00121.18 RLN72155.1 - 6.3e-83 277.9 0.8 1.6e-82 276.5 0.1 1.8 2 0 0 2 2 2 1 Triosephosphate isomerase Gp_dh_N PF00044.24 RLN72155.1 - 2.9e-37 127.0 0.1 7.8e-37 125.7 0.1 1.8 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 RLN72155.1 - 0.017 15.3 0.4 0.11 12.7 0.1 2.6 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 RLN72155.1 - 0.025 14.6 0.6 0.32 11.0 0.0 2.8 3 1 0 3 3 3 0 Zinc-binding dehydrogenase Nop25 PF09805.9 RLN72156.1 - 0.76 10.3 6.4 1.4 9.4 6.4 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) CoA_binding PF02629.19 RLN72157.1 - 1.9e-28 99.0 0.2 2.9e-28 98.4 0.2 1.3 1 0 0 1 1 1 1 CoA binding domain Leu_Phe_trans PF03588.14 RLN72157.1 - 0.034 13.6 0.0 0.043 13.4 0.0 1.1 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase ALMT PF11744.8 RLN72159.1 - 2.6 6.8 9.6 3.1 6.5 9.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter HTH_Tnp_Tc5 PF03221.16 RLN72160.1 - 0.00056 19.9 0.0 0.00087 19.3 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain TetR PF13972.6 RLN72160.1 - 0.072 12.8 0.1 0.15 11.8 0.0 1.5 2 0 0 2 2 2 0 Bacterial transcriptional repressor Peptidase_S41_N PF11918.8 RLN72163.1 - 0.018 15.3 2.0 0.046 14.0 0.1 2.6 3 0 0 3 3 3 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP F-box_4 PF15966.5 RLN72163.1 - 0.21 11.5 1.4 4.8 7.1 0.1 3.1 3 0 0 3 3 3 0 F-box IMP2_C PF18591.1 RLN72163.1 - 0.75 9.7 3.1 29 4.6 0.0 3.3 3 0 0 3 3 3 0 Immune Mapped Protein 2 (IMP2) C-terminal domain Maf1 PF09174.10 RLN72164.1 - 0.096 12.8 1.2 0.26 11.4 1.2 1.8 1 1 0 1 1 1 0 Maf1 regulator ubiquitin PF00240.23 RLN72165.1 - 1.2e-09 37.8 0.3 2.7e-05 23.8 0.0 3.2 3 0 0 3 3 3 2 Ubiquitin family Ubiquitin_2 PF14560.6 RLN72165.1 - 0.00055 20.3 0.0 0.18 12.3 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 RLN72165.1 - 0.0037 17.2 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain Alpha-mann_mid PF09261.11 RLN72165.1 - 0.0066 16.6 0.6 0.018 15.2 0.6 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain LTXXQ PF07813.12 RLN72165.1 - 1.3 9.8 8.8 0.52 11.1 2.5 2.9 3 0 0 3 3 3 0 LTXXQ motif family protein COG5 PF10392.9 RLN72165.1 - 2.4 8.3 7.2 2.1 8.5 4.0 2.3 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Tetraspanin PF00335.20 RLN72166.1 - 2.2e-05 24.3 1.8 2.6e-05 24.1 1.8 1.1 1 0 0 1 1 1 1 Tetraspanin family Prion_bPrPp PF11587.8 RLN72166.1 - 1.9 8.4 6.0 0.97 9.3 2.8 2.2 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal polyprenyl_synt PF00348.17 RLN72167.1 - 8.7e-63 211.8 0.0 3.1e-62 209.9 0.0 1.7 2 0 0 2 2 2 1 Polyprenyl synthetase DDE_Tnp_1_2 PF13586.6 RLN72167.1 - 0.079 13.3 1.0 6.6 7.2 0.3 2.5 2 1 0 2 2 2 0 Transposase DDE domain Transferase PF02458.15 RLN72171.1 - 1.7e-25 89.6 0.0 4.8e-25 88.1 0.0 1.6 1 1 0 1 1 1 1 Transferase family Joubert PF15392.6 RLN72171.1 - 0.082 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Joubert syndrome-associated Transferase PF02458.15 RLN72172.1 - 2.4e-31 108.9 0.0 5.9e-31 107.6 0.0 1.5 1 1 0 1 1 1 1 Transferase family CRM1_C PF08767.11 RLN72176.1 - 3.3e-06 26.5 0.3 8.4e-06 25.2 0.3 1.7 1 0 0 1 1 1 1 CRM1 C terminal DUF4375 PF14300.6 RLN72176.1 - 0.15 12.4 0.3 1 9.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) DUF1003 PF06210.11 RLN72176.1 - 0.18 11.9 2.0 0.22 11.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Pkinase PF00069.25 RLN72177.1 - 1.8e-36 125.9 0.0 5e-36 124.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN72177.1 - 4.8e-35 121.1 0.0 3.3e-23 82.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DEP PF00610.21 RLN72177.1 - 0.015 15.4 0.1 0.032 14.3 0.1 1.5 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pkinase PF00069.25 RLN72178.1 - 2.7e-36 125.3 0.0 8.1e-35 120.4 0.0 2.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN72178.1 - 2.7e-34 118.7 0.0 1.1e-22 80.6 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 RLN72178.1 - 0.012 15.6 0.0 0.049 13.6 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ank_2 PF12796.7 RLN72179.1 - 1.2e-34 118.7 5.8 3.1e-08 34.1 0.2 7.1 2 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN72179.1 - 6.9e-30 102.7 17.1 0.0065 16.8 0.0 14.7 7 6 9 16 16 16 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN72179.1 - 3e-29 101.0 16.6 0.00058 20.4 0.0 10.6 6 2 2 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN72179.1 - 2.6e-15 55.0 4.5 5 8.0 0.0 13.1 15 1 1 16 16 16 1 Ankyrin repeat Ank PF00023.30 RLN72179.1 - 8.6e-06 26.0 0.1 26 5.5 0.0 7.9 7 3 3 10 10 10 0 Ankyrin repeat Peptidase_S15 PF02129.18 RLN72179.1 - 0.039 13.6 0.6 7.4 6.1 0.1 3.2 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF249 PF03158.13 RLN72179.1 - 0.23 11.2 3.9 2.7 7.7 0.0 3.9 1 1 2 4 4 4 0 Multigene family 530 protein MgsA_C PF12002.8 RLN72180.1 - 2.7e-54 183.6 0.0 5.3e-54 182.6 0.0 1.5 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 RLN72180.1 - 3.1e-23 81.9 0.2 7.1e-23 80.7 0.2 1.6 1 0 0 1 1 1 1 AAA C-terminal domain RNF220 PF15926.5 RLN72180.1 - 0.00054 19.7 0.2 0.0016 18.1 0.1 1.8 2 0 0 2 2 2 1 E3 ubiquitin-protein ligase RNF220 AAA PF00004.29 RLN72180.1 - 0.015 15.7 0.0 0.039 14.4 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Nop10p PF04135.12 RLN72180.1 - 0.085 12.9 0.2 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family Sgf11 PF08209.11 RLN72180.1 - 0.56 9.8 4.5 0.13 11.8 0.9 1.8 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Pkinase_Tyr PF07714.17 RLN72181.1 - 3.2e-37 128.2 0.0 2.6e-22 79.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN72181.1 - 4.3e-37 127.9 0.0 5.5e-26 91.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain DEP PF00610.21 RLN72181.1 - 1e-05 25.5 0.0 2.4e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) APH PF01636.23 RLN72181.1 - 0.0021 18.0 0.0 0.0056 16.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN72181.1 - 0.071 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 RLN72181.1 - 0.14 11.4 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 RLN72181.1 - 0.16 11.0 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 NAM-associated PF14303.6 RLN72191.1 - 9.8e-08 32.9 0.3 1.6e-07 32.2 0.3 1.3 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain Mut7-C PF01927.16 RLN72192.1 - 2.5e-26 92.6 1.0 7.1e-26 91.1 0.3 2.1 2 0 0 2 2 2 1 Mut7-C RNAse domain tRNA_edit PF04073.15 RLN72192.1 - 3.3e-10 40.1 0.0 8.6e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain DNA_pol_A_exo1 PF01612.20 RLN72192.1 - 0.016 14.9 0.1 0.088 12.5 0.1 2.1 1 1 0 1 1 1 0 3'-5' exonuclease DUF5615 PF18480.1 RLN72192.1 - 0.13 12.1 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) WD40 PF00400.32 RLN72201.1 - 2.8e-12 47.0 12.7 0.024 15.5 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat LysM PF01476.20 RLN72201.1 - 1.2e-07 31.6 0.1 2.8e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 LysM domain TPR_12 PF13424.6 RLN72201.1 - 0.00068 19.9 1.2 0.0073 16.6 0.7 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat zf-C2HC_2 PF13913.6 RLN72201.1 - 0.0022 17.9 0.4 0.0054 16.6 0.4 1.7 1 0 0 1 1 1 1 zinc-finger of a C2HC-type TPR_7 PF13176.6 RLN72201.1 - 0.24 11.5 1.1 1.8 8.8 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat CENP-B_N PF04218.13 RLN72202.1 - 0.0001 21.9 0.1 0.0002 20.9 0.1 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 RLN72202.1 - 0.00064 19.8 0.1 0.0011 19.0 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain BrkDBD PF09607.10 RLN72202.1 - 0.00077 19.2 0.0 0.0021 17.8 0.0 1.7 1 0 0 1 1 1 1 Brinker DNA-binding domain HTH_Tnp_1 PF01527.20 RLN72202.1 - 0.0069 16.7 0.1 0.017 15.4 0.1 1.6 1 0 0 1 1 1 1 Transposase SPRY PF00622.28 RLN72203.1 - 1.2e-06 28.7 0.0 1.3e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 SPRY domain Sec7 PF01369.20 RLN72204.1 - 3.3e-59 199.7 0.9 6.6e-59 198.7 0.9 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 RLN72204.1 - 1.4e-09 38.1 1.0 1.4e-09 38.1 1.0 2.3 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal PH PF00169.29 RLN72204.1 - 9.3e-07 29.3 0.0 2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 RLN72204.1 - 0.019 14.8 2.7 0.23 11.2 0.4 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain Mfp-3 PF04202.13 RLN72205.1 - 0.24 11.8 6.0 0.56 10.6 6.0 1.6 1 0 0 1 1 1 0 Foot protein 3 WD40 PF00400.32 RLN72206.1 - 2.8e-05 24.8 0.1 0.51 11.3 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat DAPDH_C PF16654.5 RLN72206.1 - 0.066 13.1 0.0 0.087 12.7 0.0 1.2 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain Methyltransf_28 PF02636.17 RLN72207.1 - 3e-07 30.3 0.0 6.4e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TPR_1 PF00515.28 RLN72207.1 - 2.5e-05 23.9 1.8 0.0071 16.1 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN72207.1 - 3e-05 23.8 3.5 0.042 14.0 0.2 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN72207.1 - 0.0019 18.2 0.7 0.25 11.6 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN72207.1 - 0.0033 17.7 1.4 1.4 9.3 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat Methyltransf_12 PF08242.12 RLN72207.1 - 0.043 14.6 0.0 0.26 12.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain CCT PF06203.14 RLN72211.1 - 6.2e-16 58.2 12.7 1.3e-15 57.2 12.7 1.6 1 0 0 1 1 1 1 CCT motif HNH PF01844.23 RLN72212.1 - 2e-05 24.6 3.7 2e-05 24.6 3.7 1.8 2 0 0 2 2 2 1 HNH endonuclease Glyco_hydro_47 PF01532.20 RLN72213.1 - 2.4e-111 372.9 0.0 3.1e-111 372.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 RLN72213.1 - 4.8e-12 45.7 0.1 1.1e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 PA domain PRKCSH PF07915.13 RLN72213.1 - 1.5e-07 32.4 0.0 5e-07 30.6 0.0 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 RLN72213.1 - 0.0019 17.9 0.0 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Adaptin_N PF01602.20 RLN72214.1 - 7.7e-86 288.7 0.2 1.1e-85 288.2 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 RLN72214.1 - 2.2e-57 192.5 0.0 5.3e-57 191.3 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 RLN72214.1 - 1.9e-49 167.2 0.0 3.8e-49 166.2 0.0 1.5 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 RLN72214.1 - 3.3e-07 30.6 9.8 0.0051 17.2 0.0 5.7 5 2 2 7 7 7 3 HEAT repeats Cnd1 PF12717.7 RLN72214.1 - 1.8e-06 28.1 1.8 1.2e-05 25.4 0.2 2.6 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Coatomer_g_Cpla PF16381.5 RLN72214.1 - 2e-05 24.7 0.1 7.5e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 RLN72214.1 - 0.00019 21.4 0.2 1.7 9.1 0.1 5.0 4 0 0 4 4 4 1 HEAT repeat NEMP PF10225.9 RLN72215.1 - 7.2e-17 61.9 9.5 4.4e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 NEMP family Ni_hydr_CYTB PF01292.20 RLN72215.1 - 0.0048 16.5 9.1 0.01 15.5 9.1 1.6 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 Abhydrolase_9_N PF15420.6 RLN72215.1 - 0.035 14.1 5.8 0.083 12.9 5.8 1.6 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF2157 PF09925.9 RLN72215.1 - 0.14 12.0 12.0 6.5 6.5 9.2 2.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) Peptidase_U4 PF03419.13 RLN72215.1 - 0.57 9.4 10.1 19 4.4 9.5 2.4 1 1 0 1 1 1 0 Sporulation factor SpoIIGA Vma12 PF11712.8 RLN72216.1 - 0.00032 20.8 4.7 0.0013 18.8 4.7 1.9 1 1 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase C2 PF00168.30 RLN72217.1 - 5.1e-23 81.3 0.0 6.8e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 C2 domain Papilin_u7 PF16626.5 RLN72218.1 - 4 8.1 7.4 0.89 10.2 1.9 2.5 2 1 0 3 3 3 0 Linking region between Kunitz_BPTI and I-set on papilin HSP70 PF00012.20 RLN72219.1 - 1.4e-56 191.9 11.3 6.7e-54 183.1 2.8 2.3 1 1 1 2 2 2 2 Hsp70 protein TPR_1 PF00515.28 RLN72219.1 - 1.7e-12 46.6 8.8 1.1e-05 25.0 0.5 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN72219.1 - 2.9e-10 39.5 9.2 0.00012 21.9 0.9 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 RLN72219.1 - 3e-06 27.3 2.0 3e-06 27.3 2.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN72219.1 - 2.1e-05 25.1 1.1 2.1e-05 25.1 1.1 3.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN72219.1 - 3.1e-05 23.6 3.1 0.01 15.5 0.4 3.4 2 1 2 4 4 4 2 TPR repeat TPR_8 PF13181.6 RLN72219.1 - 4.5e-05 23.3 3.2 0.027 14.7 0.3 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN72219.1 - 0.00023 21.4 7.0 0.0014 18.9 1.8 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN72219.1 - 0.00033 20.8 4.3 0.0032 17.8 0.7 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN72219.1 - 0.0027 18.2 10.4 0.7 10.4 0.5 3.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN72219.1 - 0.0038 17.1 2.8 2.9 8.1 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN72219.1 - 0.0074 16.9 2.1 5.8 7.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Ubiq_cyt_C_chap PF03981.12 RLN72219.1 - 0.029 14.5 6.2 0.052 13.6 1.6 3.1 1 1 1 2 2 2 0 Ubiquinol-cytochrome C chaperone TPR_14 PF13428.6 RLN72219.1 - 0.23 12.4 10.0 1.6 9.8 0.1 4.5 3 2 1 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN72219.1 - 0.3 11.2 2.7 8.5 6.5 0.9 2.6 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat C2 PF00168.30 RLN72220.1 - 1.5e-22 79.8 0.0 2.5e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain Pex24p PF06398.11 RLN72220.1 - 7.5e-06 25.2 1.2 9.5e-06 24.8 1.2 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Aminotran_1_2 PF00155.21 RLN72221.1 - 1.2e-94 317.5 0.0 1.4e-94 317.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Nbas_N PF15492.6 RLN72221.1 - 0.047 13.0 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Linker_histone PF00538.19 RLN72222.1 - 1.8e-17 63.5 0.1 1.8e-17 63.5 0.1 2.6 2 1 0 2 2 2 1 linker histone H1 and H5 family Podoplanin PF05808.11 RLN72222.1 - 0.8 9.8 7.3 1 9.5 7.3 1.3 1 0 0 1 1 1 0 Podoplanin DUF3807 PF12720.7 RLN72222.1 - 4 7.7 15.5 5.3 7.3 15.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Endostatin PF06482.11 RLN72222.1 - 4.4 6.7 9.2 5.3 6.4 9.2 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Baculo_PEP_C PF04513.12 RLN72223.1 - 8 6.5 28.5 0.64 10.0 1.3 5.1 3 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Acyl-CoA_dh_1 PF00441.24 RLN72224.1 - 9.2e-37 126.6 0.3 1.4e-36 125.9 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RLN72224.1 - 1.4e-21 76.5 0.1 2.4e-21 75.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RLN72224.1 - 4.4e-16 59.4 0.0 7.5e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RLN72224.1 - 1.1e-09 38.9 0.0 2.8e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_ox_N PF14749.6 RLN72224.1 - 0.051 14.1 0.0 0.087 13.4 0.0 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Bromodomain PF00439.25 RLN72225.1 - 2.9e-18 65.7 0.0 5.9e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 RLN72225.1 - 9.4e-16 57.8 0.2 2.3e-15 56.5 0.2 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF2859 PF11072.8 RLN72227.1 - 0.018 14.8 0.2 0.055 13.2 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) DivIC PF04977.15 RLN72227.1 - 0.026 14.3 0.3 0.026 14.3 0.3 4.1 3 1 1 4 4 4 0 Septum formation initiator Adhesin_P1_N PF18652.1 RLN72227.1 - 0.039 14.0 0.8 0.039 14.0 0.8 2.8 2 1 1 3 3 3 0 Adhesin P1 N-terminal domain Filament PF00038.21 RLN72227.1 - 1.3 8.6 29.2 2.4 7.7 29.2 1.5 1 1 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.11 RLN72227.1 - 4.2 6.1 30.9 4.4 6.1 11.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Med14 PF08638.11 RLN72227.1 - 4.3 6.7 11.7 1.6 8.1 8.0 2.0 2 1 0 2 2 2 0 Mediator complex subunit MED14 HTH_11 PF08279.12 RLN72228.1 - 0.11 12.5 0.5 9.2 6.3 0.1 2.8 2 0 0 2 2 2 0 HTH domain DUF4107 PF13389.6 RLN72228.1 - 0.47 10.6 6.6 0.39 10.9 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4107) DUF1336 PF07059.12 RLN72229.1 - 9.5e-51 173.1 0.0 1.2e-50 172.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) FAD-oxidase_C PF02913.19 RLN72230.1 - 1.6e-41 142.6 0.0 1.7e-41 142.5 0.0 1.0 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Relaxase PF03432.14 RLN72230.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain bZIP_1 PF00170.21 RLN72231.1 - 0.00014 21.9 0.8 0.00014 21.9 0.8 21.7 17 5 8 25 25 25 5 bZIP transcription factor ATG16 PF08614.11 RLN72231.1 - 0.005 17.1 13.0 0.005 17.1 13.0 15.1 2 2 11 13 13 13 1 Autophagy protein 16 (ATG16) CCDC-167 PF15188.6 RLN72231.1 - 0.012 15.9 3.3 0.012 15.9 3.3 15.9 5 3 6 12 12 12 0 Coiled-coil domain-containing protein 167 NLE PF08154.12 RLN72231.1 - 0.25 11.9 1.2 4.6 7.9 0.1 2.9 2 0 0 2 2 2 0 NLE (NUC135) domain Sugar_tr PF00083.24 RLN72232.1 - 2.3e-48 165.2 13.9 3.2e-48 164.7 13.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN72232.1 - 1.4e-20 73.5 35.9 7.5e-14 51.4 10.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 RLN72232.1 - 0.00018 20.1 0.1 0.00018 20.1 0.1 2.2 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TssN PF17555.2 RLN72232.1 - 2.2 7.6 8.4 4.2 6.7 8.4 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssN Ank_2 PF12796.7 RLN72233.1 - 8.8e-54 180.0 16.9 4.8e-08 33.5 0.7 11.2 8 3 3 11 11 11 9 Ankyrin repeats (3 copies) zf-TRAF PF02176.18 RLN72233.1 - 5.5e-38 129.5 171.2 3.5e-05 24.4 0.5 15.9 8 4 8 16 16 16 13 TRAF-type zinc finger Ank_4 PF13637.6 RLN72233.1 - 3.3e-34 116.8 18.4 5.9e-05 23.5 0.0 11.1 9 2 2 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN72233.1 - 8.7e-33 108.7 17.3 0.0026 18.1 0.1 13.7 13 0 0 13 13 13 7 Ankyrin repeat Ank_5 PF13857.6 RLN72233.1 - 3.6e-26 90.9 20.1 5.2e-06 26.6 0.1 10.5 10 2 1 11 11 11 5 Ankyrin repeats (many copies) Ank PF00023.30 RLN72233.1 - 5e-26 90.0 20.6 0.0046 17.3 0.1 13.5 13 0 0 13 13 13 6 Ankyrin repeat Thymidylate_kin PF02223.17 RLN72234.1 - 1.5e-49 168.2 0.0 1.7e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 RLN72234.1 - 0.00034 20.9 0.1 0.00058 20.1 0.1 1.3 1 1 0 1 1 1 1 AAA domain Pkinase_Tyr PF07714.17 RLN72235.1 - 3.9e-39 134.5 0.0 4.3e-23 81.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN72235.1 - 1.9e-37 129.1 0.0 1.2e-25 90.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain DEP PF00610.21 RLN72235.1 - 9.7e-07 28.8 0.0 2.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) APH PF01636.23 RLN72235.1 - 0.0025 17.8 2.8 0.004 17.1 0.1 2.6 3 1 0 3 3 3 1 Phosphotransferase enzyme family Myc_target_1 PF15179.6 RLN72236.1 - 0.038 13.9 0.2 0.076 12.9 0.2 1.4 1 0 0 1 1 1 0 Myc target protein 1 LapA_dom PF06305.11 RLN72236.1 - 0.042 13.7 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain EphA2_TM PF14575.6 RLN72236.1 - 0.062 14.2 0.0 0.2 12.5 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1619 PF07773.11 RLN72237.1 - 4.7e-22 79.3 0.4 8e-22 78.6 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1619) Bestrophin PF01062.21 RLN72238.1 - 4.8e-17 62.3 1.5 6e-17 62.0 1.5 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF3823_C PF18003.1 RLN72239.1 - 0.031 15.0 1.4 0.072 13.8 1.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3823_C) Gram_pos_anchor PF00746.21 RLN72239.1 - 0.19 11.7 0.8 0.35 10.9 0.4 1.7 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Pkinase_Tyr PF07714.17 RLN72240.1 - 6.4e-64 215.7 0.0 8.2e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN72240.1 - 4.1e-55 187.0 0.0 5.5e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 RLN72240.1 - 0.027 13.4 0.0 0.49 9.3 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain F420_oxidored PF03807.17 RLN72241.1 - 1.1e-12 48.3 0.0 2.5e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 RLN72241.1 - 0.00045 20.7 0.0 0.00063 20.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 RLN72241.1 - 0.0021 18.2 0.0 0.0042 17.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 RLN72241.1 - 0.043 13.2 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain VPS9 PF02204.18 RLN72242.1 - 1.5e-13 50.9 0.0 2e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain MRI PF15325.6 RLN72242.1 - 0.17 13.0 3.5 0.26 12.4 3.5 1.3 1 0 0 1 1 1 0 Modulator of retrovirus infection Med17 PF10156.9 RLN72243.1 - 0.0058 15.4 6.2 0.085 11.6 0.0 3.4 3 0 0 3 3 3 2 Subunit 17 of Mediator complex CCDC53 PF10152.9 RLN72243.1 - 5.5 7.4 7.6 2.3 8.6 4.0 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Trypsin_2 PF13365.6 RLN72244.1 - 7e-19 69.2 0.0 1.8e-18 67.9 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain SAM_1 PF00536.30 RLN72244.1 - 3e-09 37.2 0.0 5.4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Trypsin PF00089.26 RLN72244.1 - 2.6e-08 33.9 0.1 1.2e-07 31.8 0.1 1.8 1 1 0 1 1 1 1 Trypsin SAM_2 PF07647.17 RLN72244.1 - 6.3e-06 26.2 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Peptidase_S46 PF10459.9 RLN72244.1 - 0.089 11.4 0.3 4.6 5.7 0.0 2.4 3 0 0 3 3 3 0 Peptidase S46 Terminase_6 PF03237.15 RLN72244.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Terminase-like family Ank_4 PF13637.6 RLN72245.1 - 1.7e-46 156.0 19.0 1.7e-07 31.6 0.0 10.6 10 3 1 11 11 11 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN72245.1 - 1.9e-43 146.9 1.9 7.6e-09 36.0 0.1 6.9 3 1 1 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN72245.1 - 2.5e-38 129.6 20.0 0.00014 22.0 0.0 15.7 4 3 13 17 17 17 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN72245.1 - 6e-27 90.7 1.9 1.1 10.1 0.0 16.4 16 1 1 17 17 17 3 Ankyrin repeat DUF5049 PF16468.5 RLN72245.1 - 2.6e-06 27.2 0.0 3.6 7.6 0.0 7.9 4 3 5 9 9 9 1 Domain of unknown function (DUF5049) Ank PF00023.30 RLN72245.1 - 2.2e-05 24.7 1.4 48 4.6 0.0 9.0 5 1 1 7 7 7 0 Ankyrin repeat DUF4411 PF14367.6 RLN72245.1 - 0.0046 16.9 0.4 1.5 8.7 0.0 3.8 1 1 3 5 5 5 1 Domain of unknown function (DUF4411) DUF3322 PF11795.8 RLN72245.1 - 0.09 12.8 8.9 30 4.6 0.0 5.8 5 2 1 6 6 6 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Ank_2 PF12796.7 RLN72246.1 - 4e-40 136.3 2.8 1.7e-09 38.1 0.1 7.0 3 3 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN72246.1 - 1e-35 121.7 17.4 4.7e-07 30.2 0.3 10.7 7 2 6 13 13 13 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN72246.1 - 6.2e-31 106.1 17.8 6.1e-05 23.2 0.0 13.2 3 3 11 14 14 14 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN72246.1 - 4.8e-23 78.7 6.1 1.1 10.0 0.1 14.2 11 3 3 14 14 14 5 Ankyrin repeat Ank PF00023.30 RLN72246.1 - 5.5e-05 23.4 2.5 63 4.3 0.0 8.1 6 3 1 7 7 7 0 Ankyrin repeat DUF5049 PF16468.5 RLN72246.1 - 9.7e-05 22.2 0.0 47 4.0 0.0 6.9 5 2 4 9 9 9 0 Domain of unknown function (DUF5049) Chlorophyllase PF07224.11 RLN72246.1 - 0.18 10.8 0.2 15 4.5 0.0 2.5 1 1 1 2 2 2 0 Chlorophyllase PDZ_6 PF17820.1 RLN72249.1 - 0.0031 17.3 0.0 0.01 15.6 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RLN72249.1 - 0.066 13.6 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 PDZ domain CDPS PF16715.5 RLN72249.1 - 0.13 11.9 0.2 0.34 10.5 0.0 1.7 2 0 0 2 2 2 0 Cyclodipeptide synthase NOG1 PF06858.14 RLN72250.1 - 2e-10 40.3 0.0 5e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOG1_N PF17835.1 RLN72250.1 - 0.0057 16.6 1.0 0.0076 16.2 0.1 1.6 2 0 0 2 2 2 1 NOG1 N-terminal helical domain CDP-OH_P_transf PF01066.21 RLN72251.1 - 3.8e-15 56.4 0.1 3.8e-15 56.4 0.1 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Med25_SD1 PF11235.8 RLN72252.1 - 0.018 15.4 1.5 0.029 14.7 1.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 Pkinase PF00069.25 RLN72253.1 - 6.9e-09 35.4 0.0 1.1e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN72253.1 - 1.5e-08 34.2 0.0 2.5e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SAP PF02037.27 RLN72254.1 - 2.6e-06 27.0 0.3 5e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 SAP domain HeH PF12949.7 RLN72254.1 - 0.11 12.2 4.1 0.21 11.3 0.0 2.8 2 1 0 2 2 2 0 HeH/LEM domain Ku PF02735.16 RLN72255.1 - 3.1e-49 167.5 0.0 4.6e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.14 RLN72255.1 - 1.6e-05 25.5 0.1 3.9e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm PRD1_DD PF11087.8 RLN72255.1 - 0.22 11.2 0.1 0.58 9.9 0.1 1.6 1 0 0 1 1 1 0 PRD1 phage membrane DNA delivery Ku_N PF03731.15 RLN72256.1 - 1.1e-09 38.4 0.0 1e-08 35.2 0.0 1.9 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Pkinase_Tyr PF07714.17 RLN72260.1 - 3.2e-46 157.7 0.0 8.4e-43 146.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN72260.1 - 4.5e-41 141.0 0.0 9.4e-39 133.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 RLN72260.1 - 0.051 12.3 0.0 0.096 11.4 0.0 1.5 1 1 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 RLN72260.1 - 0.08 12.2 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 Kinase-like HEAT_2 PF13646.6 RLN72260.1 - 0.26 11.7 4.1 0.16 12.4 0.3 2.8 3 0 0 3 3 3 0 HEAT repeats RabGAP-TBC PF00566.18 RLN72261.1 - 1.8e-12 47.4 0.1 8.1e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PH PF00169.29 RLN72261.1 - 5.7e-07 30.0 2.5 0.03 14.8 0.0 3.2 1 1 1 2 2 2 2 PH domain PH_8 PF15409.6 RLN72261.1 - 0.037 14.3 1.1 0.2 12.0 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain ADH_zinc_N_2 PF13602.6 RLN72262.1 - 6.9e-24 85.4 0.0 1.3e-23 84.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 RLN72262.1 - 3.3e-06 27.1 0.0 7.3e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN72262.1 - 1e-05 25.4 0.6 0.00016 21.5 0.3 2.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain EamA PF00892.20 RLN72263.1 - 2.3e-12 47.3 23.9 4.9e-08 33.2 4.6 2.5 2 0 0 2 2 2 2 EamA-like transporter family NTP_transf_3 PF12804.7 RLN72263.1 - 1.2e-08 35.5 0.1 2.4e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 RLN72263.1 - 0.022 14.4 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase MS_channel PF00924.18 RLN72264.1 - 7e-30 104.1 0.1 1.2e-29 103.4 0.1 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel Tagatose_6_P_K PF08013.11 RLN72264.1 - 0.19 10.3 0.1 0.25 10.0 0.1 1.1 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase Elicitin PF00964.17 RLN72265.1 - 0.0078 16.3 16.3 0.14 12.2 7.2 3.2 2 1 1 3 3 3 2 Elicitin Peptidase_S41_N PF11918.8 RLN72266.1 - 0.02 15.1 0.4 0.071 13.3 0.1 2.1 2 0 0 2 2 2 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP IMP2_C PF18591.1 RLN72266.1 - 0.33 10.9 2.6 5 7.1 0.0 3.1 3 0 0 3 3 3 0 Immune Mapped Protein 2 (IMP2) C-terminal domain F-box_4 PF15966.5 RLN72266.1 - 0.52 10.2 2.2 3.6 7.5 0.1 3.0 3 0 0 3 3 3 0 F-box Elicitin PF00964.17 RLN72268.1 - 0.2 11.8 9.1 0.25 11.4 6.6 2.4 2 1 0 2 2 2 0 Elicitin DUF4592 PF15262.6 RLN72268.1 - 7.2 7.3 8.7 0.37 11.5 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4592) FYVE PF01363.21 RLN72272.1 - 0.00048 20.2 10.7 0.001 19.2 10.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN72272.1 - 0.00052 20.2 4.5 0.0012 19.1 4.5 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger DUF1677 PF07911.13 RLN72272.1 - 0.99 9.8 6.4 2.7 8.4 6.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) ACOX PF01756.19 RLN72274.1 - 1.3e-51 174.7 0.0 2.5e-51 173.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 RLN72274.1 - 3e-28 98.9 0.1 6.8e-28 97.7 0.0 1.7 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 RLN72274.1 - 2.5e-12 46.8 0.0 6.3e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 RLN72274.1 - 0.0009 19.5 0.2 0.0027 17.9 0.2 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RLN72274.1 - 0.0039 17.8 0.0 0.016 15.9 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Pkinase PF00069.25 RLN72279.1 - 2.5e-49 168.0 0.0 1e-48 166.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN72279.1 - 4.9e-44 150.6 0.0 6.7e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RseC_MucC PF04246.12 RLN72279.1 - 0.0055 16.7 1.0 0.031 14.2 0.4 2.2 2 0 0 2 2 2 1 Positive regulator of sigma(E), RseC/MucC APH PF01636.23 RLN72279.1 - 0.033 14.1 0.2 0.12 12.2 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Wzy_C PF04932.15 RLN72279.1 - 0.033 13.8 0.0 0.076 12.6 0.0 1.6 1 1 0 1 1 1 0 O-Antigen ligase GspL_C PF12693.7 RLN72279.1 - 0.055 13.3 0.2 15 5.4 0.1 2.5 2 0 0 2 2 2 0 GspL periplasmic domain MerC PF03203.14 RLN72279.1 - 0.066 13.7 6.3 0.14 12.6 6.3 1.6 1 1 0 1 1 1 0 MerC mercury resistance protein TNFR_16_TM PF18422.1 RLN72279.1 - 0.15 12.0 0.1 0.15 12.0 0.1 2.1 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain LapA_dom PF06305.11 RLN72279.1 - 0.21 11.4 1.5 8.9 6.2 0.0 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain EphA2_TM PF14575.6 RLN72279.1 - 0.71 10.8 6.1 2.6 9.0 0.0 2.9 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.25 RLN72280.1 - 2.8e-06 26.9 0.0 3.3e-06 26.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN72280.1 - 0.001 18.4 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ABC2_membrane PF01061.24 RLN72283.1 - 1.3e-33 116.2 34.3 2e-33 115.6 34.3 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 RLN72283.1 - 4e-06 26.2 20.6 4e-06 26.2 20.6 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein PDR_CDR PF06422.12 RLN72283.1 - 4.5e-05 23.3 1.1 0.00012 21.9 0.0 2.3 2 0 0 2 2 2 1 CDR ABC transporter Oxidored_FMN PF00724.20 RLN72286.1 - 2.7e-90 303.1 0.0 3.3e-90 302.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Aldose_epim PF01263.20 RLN72287.1 - 2.4e-34 119.0 0.5 2.9e-34 118.7 0.5 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Palm_thioest PF02089.15 RLN72288.1 - 6.7e-49 166.9 0.0 8.1e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 RLN72288.1 - 5.6e-05 23.9 0.5 0.00018 22.2 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 RLN72288.1 - 0.00011 21.8 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 RLN72288.1 - 0.0016 18.2 0.0 0.0067 16.2 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_1 PF00561.20 RLN72288.1 - 0.0019 17.9 0.1 0.0046 16.6 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 RLN72288.1 - 0.022 14.3 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF3089 PF11288.8 RLN72288.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Lipase_2 PF01674.18 RLN72288.1 - 0.098 12.2 0.0 0.68 9.4 0.0 2.0 1 1 0 1 1 1 0 Lipase (class 2) Oxidored_FMN PF00724.20 RLN72289.1 - 3.7e-86 289.5 0.0 4.3e-86 289.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family CFAP91 PF14738.6 RLN72290.1 - 0.0015 18.6 10.3 0.0025 17.9 10.3 1.3 1 0 0 1 1 1 1 Cilia- and flagella-associated protein 91 TMCO5 PF14992.6 RLN72290.1 - 0.3 10.6 8.7 0.47 10.0 8.7 1.2 1 0 0 1 1 1 0 TMCO5 family DUF3450 PF11932.8 RLN72290.1 - 2.3 7.4 20.1 3.6 6.8 20.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF720 PF05302.11 RLN72290.1 - 4 7.3 16.5 7.5 6.4 16.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF720) DUF4165 PF13752.6 RLN72291.1 - 0.13 12.2 0.0 0.46 10.5 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4165) Palm_thioest PF02089.15 RLN72292.1 - 2.8e-49 168.2 0.0 3.3e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 RLN72292.1 - 5e-05 23.1 0.1 0.0001 22.0 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.14 RLN72292.1 - 0.00049 19.7 0.1 0.00094 18.7 0.1 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 RLN72292.1 - 0.0017 19.0 0.0 0.0025 18.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.18 RLN72292.1 - 0.0068 16.0 0.0 0.067 12.7 0.0 2.2 1 1 0 1 1 1 1 Lipase (class 2) PGAP1 PF07819.13 RLN72292.1 - 0.0073 16.1 0.0 0.024 14.4 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein LIDHydrolase PF10230.9 RLN72292.1 - 0.053 13.1 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase MIP PF00230.20 RLN72293.1 - 4.3e-56 190.2 8.3 5.3e-56 189.9 8.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein T5orf172 PF10544.9 RLN72293.1 - 0.18 12.3 0.7 0.3 11.6 0.7 1.3 1 0 0 1 1 1 0 T5orf172 domain DUF4605 PF15378.6 RLN72294.1 - 0.02 14.7 0.2 0.02 14.7 0.2 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4605) Pyrid_oxidase_2 PF13883.6 RLN72296.1 - 2.1e-10 40.8 0.0 2.4e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Complex1_LYR PF05347.15 RLN72297.1 - 5.3e-10 39.2 3.1 6.8e-10 38.9 3.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 RLN72297.1 - 0.02 15.5 1.1 0.032 14.8 1.0 1.6 1 1 0 1 1 1 0 Complex1_LYR-like DUF2654 PF10849.8 RLN72297.1 - 0.35 11.1 3.8 0.19 12.0 1.3 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2654) Oxidored_FMN PF00724.20 RLN72298.1 - 1.4e-80 271.2 0.0 1.8e-80 270.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Palm_thioest PF02089.15 RLN72298.1 - 1.8e-48 165.5 0.0 2.9e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 RLN72298.1 - 2.9e-06 27.1 0.0 6.3e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN72298.1 - 0.00064 20.4 0.0 0.0014 19.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 RLN72298.1 - 0.00085 18.9 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 RLN72298.1 - 0.00089 18.9 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 RLN72298.1 - 0.0022 17.8 0.0 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein DUF3089 PF11288.8 RLN72298.1 - 0.03 13.8 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) CSN8_PSD8_EIF3K PF10075.9 RLN72301.1 - 5e-11 42.8 0.1 1.3e-10 41.4 0.1 1.6 1 1 1 2 2 2 1 CSN8/PSMD8/EIF3K family UTP15_C PF09384.10 RLN72302.1 - 8.3e-46 155.3 0.2 1.3e-45 154.7 0.2 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 RLN72302.1 - 2.4e-23 82.0 13.6 1.3e-05 25.9 0.2 6.6 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN72302.1 - 2.6e-08 34.1 0.0 0.008 16.4 0.0 3.2 2 2 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN72302.1 - 0.096 11.3 0.1 1.3 7.6 0.0 2.7 2 2 1 3 3 3 0 Nucleoporin Nup120/160 CobT PF06213.12 RLN72303.1 - 0.029 13.8 23.2 0.033 13.6 23.2 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Polyoma_lg_T_C PF06431.11 RLN72303.1 - 0.12 11.2 6.2 0.14 11.0 6.2 1.0 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus FAM91_C PF14648.6 RLN72303.1 - 0.15 10.8 1.2 0.15 10.8 1.2 1.0 1 0 0 1 1 1 0 FAM91 C-terminus NOA36 PF06524.12 RLN72303.1 - 0.57 9.5 18.3 0.56 9.5 18.3 1.0 1 0 0 1 1 1 0 NOA36 protein RPN2_C PF18004.1 RLN72303.1 - 1.1 9.1 11.2 1.1 9.1 11.2 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain GEN1_C PF18380.1 RLN72303.1 - 1.7 9.6 10.3 1.8 9.5 10.3 1.1 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain DNA_pol_phi PF04931.13 RLN72303.1 - 2.7 6.0 27.7 2.8 5.9 27.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi DARPP-32 PF05395.12 RLN72303.1 - 3.1 8.0 15.5 3.1 8.0 15.5 1.0 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Nop14 PF04147.12 RLN72303.1 - 3.4 5.8 22.5 3.4 5.8 22.5 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RLN72303.1 - 3.6 5.8 19.1 3.8 5.7 19.1 1.0 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.6 RLN72303.1 - 3.8 7.7 8.9 4.6 7.4 8.9 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal MRNIP PF15749.5 RLN72303.1 - 3.8 8.3 7.2 4.3 8.1 7.2 1.1 1 0 0 1 1 1 0 MRN-interacting protein RNA_pol_Rpc4 PF05132.14 RLN72303.1 - 4.1 7.8 6.9 4.2 7.8 6.9 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 TRAP_alpha PF03896.16 RLN72303.1 - 5.2 6.2 14.1 5.4 6.1 14.1 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PPP4R2 PF09184.11 RLN72303.1 - 6.6 6.2 19.6 6.6 6.2 19.6 1.1 1 0 0 1 1 1 0 PPP4R2 TPR_1 PF00515.28 RLN72304.1 - 6.9e-17 60.5 4.5 0.0036 17.1 0.0 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 RLN72304.1 - 9.9e-16 57.8 13.6 0.00074 19.8 0.6 7.2 7 2 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN72304.1 - 1e-14 53.4 15.8 0.0064 16.5 0.0 9.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN72304.1 - 2.6e-10 39.6 8.9 0.04 13.9 0.0 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN72304.1 - 3e-08 33.2 9.1 0.018 15.2 0.0 8.0 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN72304.1 - 7.6e-06 26.4 30.6 0.028 14.9 0.4 8.4 7 2 2 9 9 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN72304.1 - 1.2e-05 25.4 4.2 0.44 10.8 0.0 6.1 5 1 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RLN72304.1 - 6e-05 23.5 20.3 2.8 9.0 0.1 9.7 9 1 2 11 11 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN72304.1 - 6.1e-05 23.1 3.2 0.058 13.6 0.1 5.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN72304.1 - 9.8e-05 22.1 11.3 0.15 12.0 0.0 7.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN72304.1 - 0.006 17.2 0.7 0.006 17.2 0.7 7.2 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_3 PF07720.12 RLN72304.1 - 0.024 14.6 0.4 37 4.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC5 PF12862.7 RLN72304.1 - 0.027 14.6 0.1 0.18 11.9 0.0 2.5 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 5 MFS_4 PF06779.14 RLN72304.1 - 0.027 13.8 0.2 0.044 13.1 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB TPR_4 PF07721.14 RLN72304.1 - 0.16 12.7 7.4 2.9 8.8 0.0 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN72304.1 - 0.63 10.8 14.3 40 5.1 0.0 7.8 9 0 0 9 9 8 0 Tetratricopeptide repeat HSA PF07529.13 RLN72308.1 - 1.4e-09 38.1 5.8 2.4e-08 34.2 5.8 2.7 1 1 0 1 1 1 1 HSA SNF2_N PF00176.23 RLN72308.1 - 2.6e-09 36.3 1.0 3.9e-08 32.4 1.0 2.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Myb_DNA-bind_6 PF13921.6 RLN72308.1 - 3.5e-06 27.2 0.2 1.2e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 RLN72308.1 - 5.7e-06 26.4 0.0 1.8e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain CCDC23 PF15674.5 RLN72308.1 - 0.01 15.8 0.3 0.043 13.8 0.3 2.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 23 WIYLD PF10440.9 RLN72308.1 - 0.096 12.5 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain Cyt-b5 PF00173.28 RLN72309.1 - 1.7e-16 60.1 0.1 1.9e-16 60.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Jiv90 PF14901.6 RLN72309.1 - 0.017 15.3 0.1 0.02 15.0 0.1 1.2 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone Thioredoxin PF00085.20 RLN72311.1 - 5.5e-38 129.1 0.6 3.8e-24 84.6 0.1 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.6 RLN72311.1 - 1.6e-06 28.2 0.5 0.02 15.1 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 RLN72311.1 - 4.3e-06 27.1 0.1 0.0046 17.4 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RLN72311.1 - 1.2e-05 25.5 0.1 0.058 13.7 0.0 3.2 2 1 1 3 3 3 1 Thioredoxin-like TraF PF13728.6 RLN72311.1 - 5.6e-05 23.1 0.1 0.0005 20.0 0.0 2.2 2 0 0 2 2 2 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 RLN72311.1 - 0.0014 18.0 1.0 0.0049 16.3 0.0 2.1 2 1 1 3 3 3 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 RLN72311.1 - 0.0035 17.1 2.1 0.16 11.8 0.1 2.8 2 1 1 3 3 3 1 Thioredoxin Glutaredoxin PF00462.24 RLN72311.1 - 0.024 14.8 1.0 3.4 8.0 0.2 2.7 2 0 0 2 2 2 0 Glutaredoxin Thioredoxin_6 PF13848.6 RLN72311.1 - 0.078 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_3 PF13192.6 RLN72311.1 - 0.19 11.8 0.7 0.53 10.4 0.1 2.0 2 0 0 2 2 2 0 Thioredoxin domain DUF3523 PF12037.8 RLN72313.1 - 2.8e-42 144.9 27.8 2.8e-42 144.9 27.8 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 RLN72313.1 - 4.8e-22 78.8 0.0 1.3e-21 77.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN72313.1 - 1.2e-05 25.6 1.5 0.0014 18.9 0.0 3.4 3 2 0 3 3 3 1 AAA domain AAA_5 PF07728.14 RLN72313.1 - 2.4e-05 24.4 0.2 0.0003 20.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RLN72313.1 - 2.9e-05 23.9 0.0 9.2e-05 22.2 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 RLN72313.1 - 4.7e-05 22.9 0.2 0.00016 21.1 0.1 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zot PF05707.12 RLN72313.1 - 0.00018 21.2 0.3 0.28 10.8 0.0 3.2 3 0 0 3 3 3 1 Zonular occludens toxin (Zot) AAA_33 PF13671.6 RLN72313.1 - 0.0005 20.3 4.3 0.00068 19.8 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN72313.1 - 0.00086 19.7 0.0 0.00086 19.7 0.0 4.3 2 2 2 4 4 3 1 AAA ATPase domain AAA_3 PF07726.11 RLN72313.1 - 0.0023 17.8 0.2 0.013 15.4 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 RLN72313.1 - 0.0066 16.2 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RLN72313.1 - 0.0072 16.9 0.0 0.0072 16.9 0.0 3.0 2 2 0 2 2 1 1 AAA domain Rad17 PF03215.15 RLN72313.1 - 0.0086 16.0 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain TsaE PF02367.17 RLN72313.1 - 0.013 15.5 0.1 0.098 12.7 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 RLN72313.1 - 0.022 15.2 0.1 0.022 15.2 0.1 3.2 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RLN72313.1 - 0.039 13.5 0.0 0.081 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 RLN72313.1 - 0.041 13.4 3.8 0.37 10.3 0.0 3.2 2 1 0 3 3 3 0 AAA domain MRF_C1 PF13887.6 RLN72313.1 - 0.042 13.0 0.3 0.24 10.6 0.0 2.3 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 RNA_helicase PF00910.22 RLN72313.1 - 0.046 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 RLN72313.1 - 0.075 13.1 0.0 0.24 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain 2OG-FeII_Oxy_3 PF13640.6 RLN72315.1 - 5.5e-15 56.0 0.1 1.3e-14 54.8 0.1 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 RLN72315.1 - 3.1e-05 24.4 0.1 8.2e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RskA PF10099.9 RLN72315.1 - 0.2 11.9 3.3 0.31 11.3 3.3 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SecA_DEAD PF07517.14 RLN72320.1 - 1.2e-06 28.0 0.0 2.9e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 SecA DEAD-like domain CHB_HEX PF03173.13 RLN72321.1 - 0.11 12.2 0.5 0.2 11.3 0.5 1.5 1 1 0 1 1 1 0 Putative carbohydrate binding domain SET PF00856.28 RLN72323.1 - 0.00061 20.2 0.6 0.0041 17.5 0.1 2.1 1 1 0 2 2 2 1 SET domain TPR_12 PF13424.6 RLN72323.1 - 0.012 15.9 4.4 0.23 11.8 1.8 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN72323.1 - 0.16 11.9 5.7 0.21 11.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CC2-LZ PF16516.5 RLN72323.1 - 0.19 12.1 2.0 0.34 11.3 0.4 2.1 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator zf-MYND PF01753.18 RLN72324.1 - 1.4e-11 44.2 15.6 2.1e-11 43.7 15.6 1.3 1 0 0 1 1 1 1 MYND finger RRM_1 PF00076.22 RLN72325.1 - 1.4e-18 66.5 0.0 2.3e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN72325.1 - 0.0016 18.6 0.8 0.0053 16.9 0.1 2.2 2 1 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 RLN72325.1 - 0.017 14.7 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5427 PF10310.9 RLN72325.1 - 0.045 12.7 10.6 0.056 12.4 10.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF4632 PF15451.6 RLN72325.1 - 0.049 13.7 8.9 0.89 9.7 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) BBS2_C PF14782.6 RLN72325.1 - 0.058 12.2 5.7 0.11 11.2 5.7 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal RRN3 PF05327.11 RLN72325.1 - 0.086 11.4 4.2 0.11 11.0 4.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NARP1 PF12569.8 RLN72325.1 - 0.61 8.9 13.9 0.86 8.4 13.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 eIF3_subunit PF08597.10 RLN72325.1 - 1.1 9.1 20.2 1.6 8.6 20.2 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit PIEZO PF15917.5 RLN72325.1 - 1.3 8.4 11.4 2.1 7.7 11.4 1.3 1 0 0 1 1 1 0 Piezo SAGA-Tad1 PF12767.7 RLN72325.1 - 1.3 8.7 8.7 1.7 8.3 8.7 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit AIF_C PF14721.6 RLN72325.1 - 2.6 8.4 4.7 4.9 7.5 4.7 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Sec62 PF03839.16 RLN72325.1 - 5.7 6.4 10.4 8.6 5.8 10.4 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Methyltransf_25 PF13649.6 RLN72326.1 - 3.1e-24 85.5 0.1 8.5e-19 68.1 0.0 3.3 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 RLN72326.1 - 5.2e-24 84.7 0.2 3.1e-18 66.2 0.0 3.3 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 RLN72326.1 - 5.3e-22 78.4 0.0 1.3e-19 70.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN72326.1 - 1.3e-21 77.0 0.0 8.2e-16 58.2 0.0 2.6 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 RLN72326.1 - 1.3e-17 64.3 0.0 1.5e-12 48.1 0.0 3.2 3 0 0 3 3 3 2 Methyltransferase domain CMAS PF02353.20 RLN72326.1 - 5e-15 55.5 0.1 1e-14 54.5 0.1 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase CheR PF01739.18 RLN72326.1 - 9.9e-11 41.5 0.0 0.0012 18.3 0.0 3.3 2 1 1 3 3 3 2 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 RLN72326.1 - 7.6e-09 35.2 0.0 3.8e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 RLN72326.1 - 3.7e-08 32.6 0.0 5.8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.19 RLN72326.1 - 7e-08 32.5 0.0 1.4e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPMT PF05724.11 RLN72326.1 - 4e-07 29.9 0.0 7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MetW PF07021.12 RLN72326.1 - 0.00019 21.1 0.1 0.0006 19.5 0.0 1.8 2 1 0 2 2 2 1 Methionine biosynthesis protein MetW MTS PF05175.14 RLN72326.1 - 0.0016 18.0 0.0 0.004 16.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 RLN72326.1 - 0.0035 17.4 0.0 0.0068 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 RLN72326.1 - 0.0064 15.1 0.0 0.028 13.0 0.0 1.9 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF938 PF06080.12 RLN72326.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DOT1 PF08123.13 RLN72326.1 - 0.012 15.2 0.3 0.077 12.5 0.1 2.4 3 0 0 3 3 3 0 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 RLN72326.1 - 0.036 13.5 0.0 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Pox_MCEL PF03291.16 RLN72326.1 - 0.045 12.9 0.0 0.096 11.8 0.0 1.6 1 0 0 1 1 1 0 mRNA capping enzyme WD40 PF00400.32 RLN72327.1 - 2.1e-11 44.2 6.4 0.005 17.7 0.0 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat Lactonase PF10282.9 RLN72327.1 - 0.00083 18.7 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller ANAPC4_WD40 PF12894.7 RLN72327.1 - 0.0079 16.5 0.0 15 6.0 0.0 3.9 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 RLN72327.1 - 0.075 12.6 0.0 1.3 8.5 0.0 2.3 2 1 0 2 2 2 0 PQQ-like domain MatE PF01554.18 RLN72329.1 - 4.5e-24 84.9 7.9 4.5e-24 84.9 7.9 1.9 2 0 0 2 2 2 1 MatE Polysacc_synt PF01943.17 RLN72329.1 - 2.1e-05 24.1 4.3 2.4e-05 23.8 4.3 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Pkinase_Tyr PF07714.17 RLN72331.1 - 4.1e-40 137.7 0.0 7.5e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN72331.1 - 1.1e-33 116.8 0.0 8.3e-33 113.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain zinc_ribbon_15 PF17032.5 RLN72331.1 - 6.6e-05 23.6 0.4 0.00015 22.4 0.4 1.6 1 0 0 1 1 1 1 zinc-ribbon family DZR PF12773.7 RLN72331.1 - 0.00025 21.0 0.5 0.00061 19.8 0.5 1.6 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 RLN72331.1 - 0.0007 19.2 2.3 0.0019 17.9 2.3 1.8 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 RLN72331.1 - 0.0029 16.9 1.4 0.007 15.7 1.4 1.7 1 0 0 1 1 1 1 zinc-ribbon domain HTH_Tnp_Tc5 PF03221.16 RLN72332.1 - 2.3e-13 49.9 0.0 3.5e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain SecG PF03840.14 RLN72334.1 - 7.5 6.7 9.6 28 4.9 4.9 2.5 2 1 0 2 2 2 0 Preprotein translocase SecG subunit Ribonuclease_3 PF00636.26 RLN72336.1 - 6.1e-34 116.8 0.0 1.2e-15 58.0 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 RLN72336.1 - 5.9e-21 74.4 0.5 3.6e-20 71.9 0.2 2.5 2 1 0 2 2 2 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 RLN72336.1 - 3e-19 69.5 0.0 1e-08 35.4 0.0 4.4 4 1 0 4 4 4 3 Ribonuclease-III-like DUF848 PF05852.11 RLN72336.1 - 0.05 13.7 0.1 0.3 11.2 0.1 2.2 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) CDC45 PF02724.14 RLN72336.1 - 0.67 8.2 4.1 1 7.6 4.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RLN72336.1 - 2.8 6.0 10.8 3.4 5.8 7.1 2.0 2 0 0 2 2 2 0 Nop14-like family CAF1 PF04857.20 RLN72338.1 - 3.3e-65 220.3 0.0 1.1e-64 218.6 0.0 1.7 1 1 0 1 1 1 1 CAF1 family ribonuclease Acetyltransf_10 PF13673.7 RLN72339.1 - 5.4e-12 45.8 0.0 6.6e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN72339.1 - 5.7e-09 36.3 0.0 7.8e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RLN72339.1 - 2.6e-08 34.1 0.0 3.7e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 RLN72339.1 - 0.00053 19.9 0.0 0.00085 19.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 RLN72339.1 - 0.02 15.0 0.0 0.066 13.3 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain HSP70 PF00012.20 RLN72340.1 - 6.7e-51 173.2 0.0 9.4e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN72340.1 - 0.0023 16.8 0.3 0.072 11.9 0.0 2.5 2 0 0 2 2 2 2 MreB/Mbl protein ATP-synt_Z PF16594.5 RLN72340.1 - 0.018 14.5 0.1 0.038 13.5 0.1 1.5 1 0 0 1 1 1 0 Putative AtpZ or ATP-synthase-associated FYVE PF01363.21 RLN72341.1 - 0.0055 16.8 16.7 0.013 15.6 16.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger C1_1 PF00130.22 RLN72341.1 - 0.43 10.5 8.8 1.1 9.2 8.8 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 RLN72341.1 - 3.5 7.9 12.1 8.3 6.7 12.1 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger Acetyltransf_10 PF13673.7 RLN72342.1 - 3.3e-13 49.7 0.0 3.8e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN72342.1 - 2.3e-08 34.3 0.1 3.6e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RLN72342.1 - 7.6e-08 32.6 0.0 1e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 RLN72342.1 - 0.0011 19.7 2.1 0.019 15.7 0.4 2.6 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 RLN72342.1 - 0.0042 17.2 0.0 0.0079 16.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Ad_Cy_reg PF16701.5 RLN72342.1 - 0.053 13.3 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase regulatory domain A_thal_3526 PF09713.10 RLN72343.1 - 6.5e-23 80.7 0.0 9.9e-23 80.1 0.0 1.3 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) LRR_8 PF13855.6 RLN72344.1 - 3.4e-30 103.6 26.6 1e-08 34.8 2.7 5.6 3 2 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 RLN72344.1 - 1e-27 95.7 31.0 3e-08 33.8 2.4 7.4 6 1 3 9 9 9 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN72344.1 - 9.1e-13 46.8 19.2 1.8 9.4 0.4 10.3 11 0 0 11 11 11 4 Leucine Rich Repeat LRR_9 PF14580.6 RLN72344.1 - 3.9e-08 33.0 13.4 1.3e-05 24.8 1.7 4.3 1 1 3 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.6 RLN72344.1 - 0.0014 18.5 21.5 2.3 8.5 0.0 8.6 9 0 0 9 9 9 1 Leucine Rich repeat DUF2322 PF10084.9 RLN72344.1 - 0.018 15.1 0.3 0.055 13.5 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2322) TAF6_C PF07571.13 RLN72345.1 - 1.4e-17 63.8 0.0 3.8e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 RLN72345.1 - 1.5e-16 60.3 0.0 3.2e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 RLN72345.1 - 0.03 14.4 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit C2 PF00168.30 RLN72346.1 - 2.8e-14 53.2 0.0 1.6e-13 50.8 0.0 2.3 2 0 0 2 2 2 1 C2 domain LRR_9 PF14580.6 RLN72346.1 - 5.3e-12 45.6 1.6 6.4e-11 42.1 0.5 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 RLN72346.1 - 1.6e-10 40.5 14.7 9e-10 38.2 7.9 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 RLN72346.1 - 1.9e-08 34.4 17.1 0.00011 22.5 3.1 3.7 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN72346.1 - 0.078 13.6 7.2 4.9 8.1 0.0 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat SWIRM-assoc_2 PF16496.5 RLN72346.1 - 0.28 10.0 3.4 0.71 8.7 3.4 1.6 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal LRR_6 PF13516.6 RLN72346.1 - 3.3 8.0 11.0 54 4.2 0.5 4.7 4 0 0 4 4 4 0 Leucine Rich repeat Ly49 PF08391.10 RLN72346.1 - 4.9 7.5 5.1 12 6.3 1.5 2.9 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Metallophos PF00149.28 RLN72348.1 - 3.7e-16 60.3 0.0 6.5e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4150 PF13665.6 RLN72348.1 - 0.027 14.6 0.1 0.065 13.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4150) PLAC8 PF04749.17 RLN72353.1 - 5.4e-17 62.6 13.9 1.6e-16 61.1 13.9 1.7 1 1 0 1 1 1 1 PLAC8 family DUF898 PF05987.13 RLN72353.1 - 0.065 12.3 0.1 0.09 11.8 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF2183 PF09949.9 RLN72355.1 - 0.0055 17.0 0.1 0.035 14.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) DUF2207 PF09972.9 RLN72355.1 - 0.17 10.6 0.1 0.3 9.8 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2157 PF09925.9 RLN72355.1 - 0.21 11.3 2.7 0.41 10.4 2.7 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Peptidase_M3 PF01432.20 RLN72356.1 - 7.6e-122 407.9 0.0 9.4e-122 407.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 RLN72356.1 - 0.1 12.2 0.2 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Nas2_N PF18265.1 RLN72356.1 - 0.17 11.8 0.5 0.71 9.8 0.0 2.2 2 0 0 2 2 2 0 Nas2 N_terminal domain PH PF00169.29 RLN72357.1 - 1e-06 29.2 0.9 4.7e-06 27.0 0.9 1.9 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN72357.1 - 0.0047 17.2 0.1 0.0096 16.2 0.1 1.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 RLN72357.1 - 0.054 13.9 4.3 0.56 10.7 1.0 2.5 2 1 1 3 3 3 0 Pleckstrin homology domain FAM220 PF15487.6 RLN72357.1 - 0.091 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 FAM220 family HTH_Tnp_Tc5 PF03221.16 RLN72359.1 - 0.026 14.5 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 RLN72363.1 - 6.9e-25 87.7 0.0 1.2e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN72363.1 - 9.4e-10 38.4 0.0 2.3e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Rhomboid PF01694.22 RLN72364.1 - 2.7e-25 89.1 9.2 4.5e-25 88.4 9.2 1.3 1 0 0 1 1 1 1 Rhomboid family Pkinase_Tyr PF07714.17 RLN72365.1 - 5e-41 140.7 0.0 3.9e-26 91.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN72365.1 - 8.5e-38 130.2 0.0 7.4e-26 91.1 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Arm PF00514.23 RLN72365.1 - 6.6e-17 60.9 2.8 0.09 12.9 0.0 8.2 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN72365.1 - 0.00018 21.8 17.0 0.0018 18.6 2.0 4.0 4 1 1 5 5 5 3 HEAT repeats Kinase-like PF14531.6 RLN72365.1 - 0.017 14.5 0.0 0.97 8.7 0.0 2.5 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 RLN72365.1 - 0.032 13.6 0.0 2 7.7 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN72365.1 - 0.07 13.0 0.0 0.07 13.0 0.0 3.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN72365.1 - 0.14 10.9 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_C48 PF02902.19 RLN72367.1 - 1.2e-12 48.2 0.0 2.7e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MULE PF10551.9 RLN72368.1 - 5.6e-19 68.4 0.8 3.1e-18 66.0 0.2 2.5 2 0 0 2 2 2 1 MULE transposase domain DUF5575 PF17738.1 RLN72368.1 - 1.2e-07 31.1 1.4 1.4e-07 30.9 0.1 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5575) DDE_Tnp_ISL3 PF01610.17 RLN72368.1 - 0.038 13.7 0.2 0.038 13.7 0.2 2.2 3 0 0 3 3 3 0 Transposase Troponin PF00992.20 RLN72368.1 - 0.053 13.8 1.0 0.1 12.9 1.0 1.5 1 0 0 1 1 1 0 Troponin ABC_membrane PF00664.23 RLN72378.1 - 7.1e-06 25.9 0.1 8.1e-06 25.7 0.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region MFS_2 PF13347.6 RLN72379.1 - 8.2e-12 44.4 11.8 8.2e-12 44.4 11.8 2.3 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.16 RLN72380.1 - 1.5e-11 43.8 45.5 5.1e-06 25.6 14.5 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 RLN72380.1 - 1.7e-11 43.4 14.6 1.7e-11 43.4 14.6 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein Ank_2 PF12796.7 RLN72381.1 - 1.1e-80 266.2 5.3 1.1e-12 48.3 0.0 7.8 2 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN72381.1 - 8.1e-62 204.8 9.2 4.9e-09 36.5 0.2 8.9 6 2 4 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN72381.1 - 1.4e-61 197.1 12.2 8.5e-05 22.7 0.1 13.5 13 0 0 13 13 13 12 Ankyrin repeat Ank PF00023.30 RLN72381.1 - 2.9e-60 198.2 25.6 2.7e-06 27.6 0.1 13.6 14 0 0 14 14 14 12 Ankyrin repeat Ank_5 PF13857.6 RLN72381.1 - 5.7e-59 195.4 28.2 1.6e-08 34.6 0.1 12.1 2 2 11 13 13 13 12 Ankyrin repeats (many copies) MFS_2 PF13347.6 RLN72382.1 - 3.7e-12 45.5 14.1 3.7e-12 45.5 14.1 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 RLN72382.1 - 6e-11 41.9 61.6 1.9e-09 36.9 33.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RLN72383.1 - 5.8e-11 41.6 14.6 5.8e-11 41.6 14.6 2.3 2 0 0 2 2 2 1 MFS/sugar transport protein SpoV PF08183.11 RLN72383.1 - 0.018 15.0 1.1 4.6 7.3 0.2 2.6 2 0 0 2 2 2 0 Stage V sporulation protein family HCMV_UL124 PF17609.2 RLN72383.1 - 0.088 13.0 0.1 0.24 11.6 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function Ribonuclease_3 PF00636.26 RLN72386.1 - 5.9e-07 30.1 0.2 6.9e-05 23.4 0.0 2.8 3 0 0 3 3 3 1 Ribonuclease III domain HutP PF09021.11 RLN72386.1 - 0.048 14.0 0.2 0.13 12.6 0.2 1.7 1 0 0 1 1 1 0 HutP COG4 PF08318.12 RLN72386.1 - 0.088 11.9 0.2 0.15 11.1 0.2 1.3 1 0 0 1 1 1 0 COG4 transport protein R3H PF01424.22 RLN72386.1 - 0.096 12.7 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 R3H domain E3_UbLigase_R4 PF13764.6 RLN72386.1 - 0.34 9.0 2.2 0.51 8.4 2.2 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 DUF1764 PF08576.10 RLN72386.1 - 0.56 11.1 3.4 2 9.3 3.4 1.9 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) T2SSM PF04612.12 RLN72386.1 - 2.1 8.4 7.8 0.18 11.8 0.9 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M PhoLip_ATPase_C PF16212.5 RLN72390.1 - 9.5e-65 218.8 23.0 9.5e-65 218.8 23.0 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RLN72390.1 - 1.6e-21 75.8 0.0 6.9e-21 73.7 0.0 2.1 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 RLN72390.1 - 4.8e-10 39.4 0.0 6.8e-09 35.7 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RLN72390.1 - 3.7e-09 37.2 0.1 0.0028 18.0 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RLN72390.1 - 6.8e-05 22.5 0.0 0.00037 20.1 0.0 2.2 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RLN72390.1 - 0.0028 17.5 0.2 0.0097 15.7 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF5313 PF17240.2 RLN72390.1 - 0.022 15.2 0.2 0.076 13.5 0.2 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5313) SET PF00856.28 RLN72393.1 - 6e-18 65.8 0.0 3.1e-17 63.5 0.0 2.3 1 1 0 1 1 1 1 SET domain Glyco_hydro_72 PF03198.14 RLN72393.1 - 1.1e-16 61.0 0.0 1.7e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Pkinase PF00069.25 RLN72393.1 - 4.2e-16 59.1 0.0 7.3e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain AWS PF17907.1 RLN72393.1 - 2.9e-08 33.6 2.9 6.9e-08 32.4 2.9 1.7 1 0 0 1 1 1 1 AWS domain Cyclin_N PF00134.23 RLN72393.1 - 0.0032 17.2 0.1 0.006 16.3 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Kinase-like PF14531.6 RLN72393.1 - 0.068 12.5 0.0 0.19 11.0 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Glyco_hydro_72 PF03198.14 RLN72394.1 - 8.5e-40 136.9 0.0 1.1e-39 136.5 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 RLN72394.1 - 0.041 13.3 0.0 0.28 10.6 0.0 2.2 2 1 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Ctr PF04145.15 RLN72395.1 - 1.1e-19 71.6 0.5 1.8e-19 70.9 0.5 1.3 1 0 0 1 1 1 1 Ctr copper transporter family MA3 PF02847.17 RLN72396.1 - 9.6e-46 154.4 0.2 1.7e-21 76.3 0.1 2.3 2 0 0 2 2 2 2 MA3 domain Ctr PF04145.15 RLN72396.1 - 4.2e-13 50.2 1.6 2.4e-12 47.7 1.6 2.0 1 1 0 1 1 1 1 Ctr copper transporter family Tic110 PF16940.5 RLN72398.1 - 0.0041 15.7 0.0 0.0088 14.6 0.0 1.4 1 0 0 1 1 1 1 Chloroplast envelope transporter Dus PF01207.17 RLN72399.1 - 1.2e-77 261.1 0.0 1.8e-77 260.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 RLN72399.1 - 9.2e-05 22.0 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 RLN72399.1 - 0.00018 20.9 0.1 0.00037 19.9 0.1 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.17 RLN72399.1 - 0.00074 18.9 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase DHO_dh PF01180.21 RLN72399.1 - 0.0022 17.2 0.0 0.068 12.4 0.0 2.1 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase NanE PF04131.14 RLN72399.1 - 0.003 16.8 0.0 0.0059 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.18 RLN72399.1 - 0.01 14.9 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase G3P_antiterm PF04309.12 RLN72399.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator NMO PF03060.15 RLN72399.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase IMPDH PF00478.25 RLN72399.1 - 0.076 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain PAP_central PF04928.17 RLN72401.1 - 3.7e-70 235.8 0.0 1e-69 234.3 0.0 1.7 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 RLN72401.1 - 1.8e-07 30.9 0.2 1.2e-06 28.3 0.1 2.3 1 1 1 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 RLN72401.1 - 4.4e-07 30.1 0.0 9.3e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4269 PF14091.6 RLN72401.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) Laminin_G_3 PF13385.6 RLN72404.1 - 1e-06 29.0 0.0 3.9e-06 27.1 0.0 2.0 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily F5_F8_type_C PF00754.25 RLN72404.1 - 0.0002 21.4 0.5 0.087 13.0 0.1 3.9 3 0 0 3 3 3 1 F5/8 type C domain Calx-beta PF03160.14 RLN72404.1 - 0.00062 19.9 6.4 0.19 12.0 0.1 5.7 7 0 0 7 7 7 2 Calx-beta domain Ank_2 PF12796.7 RLN72408.1 - 1.8e-11 44.5 0.3 0.0012 19.4 0.0 2.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RLN72408.1 - 3.9e-11 42.9 0.3 9.9e-05 22.6 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 RLN72408.1 - 3e-10 40.4 0.1 0.00076 20.0 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN72408.1 - 3.3e-10 39.3 0.6 0.048 14.2 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 RLN72408.1 - 1.2e-07 31.9 0.6 0.1 13.0 0.0 3.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) bPH_1 PF08000.11 RLN72409.1 - 5.5e-06 26.5 0.0 5.5e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial PH domain bPH_1 PF08000.11 RLN72410.1 - 5.5e-20 71.7 0.1 8.4e-20 71.1 0.1 1.2 1 0 0 1 1 1 1 Bacterial PH domain GFO_IDH_MocA_C PF02894.17 RLN72413.1 - 1.8e-05 24.7 0.0 3.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 RLN72413.1 - 0.00022 22.1 0.2 0.5 11.2 0.0 2.4 1 1 1 2 2 2 2 Oxidoreductase family, NAD-binding Rossmann fold Gp_dh_N PF00044.24 RLN72413.1 - 0.028 14.8 0.0 0.099 13.0 0.0 1.9 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 RLN72413.1 - 0.12 12.5 0.0 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Neurensin PF14927.6 RLN72416.1 - 0.0095 15.6 0.3 0.036 13.8 0.3 2.1 1 0 0 1 1 1 1 Neurensin Adaptin_N PF01602.20 RLN72416.1 - 0.031 12.9 0.0 0.049 12.2 0.0 1.2 1 0 0 1 1 1 0 Adaptin N terminal region PRP1_N PF06424.12 RLN72422.1 - 6e-52 176.0 1.5 1.3e-51 174.8 0.1 2.2 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 RLN72422.1 - 2.9e-25 86.8 29.4 0.0088 16.8 0.0 13.4 7 5 7 14 14 14 8 Tetratricopeptide repeat TPR_19 PF14559.6 RLN72422.1 - 3.4e-22 78.7 10.9 2.1e-06 28.1 0.0 9.2 7 3 3 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 RLN72422.1 - 2e-07 30.7 6.2 18 5.8 0.0 7.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN72422.1 - 4.5e-07 29.8 0.3 45 4.7 0.1 8.5 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN72422.1 - 9.2e-06 26.2 13.6 0.062 14.0 0.1 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN72422.1 - 1.2e-05 25.1 7.9 3.4 8.0 0.0 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN72422.1 - 0.0084 15.9 0.3 2.7 7.9 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat IQ PF00612.27 RLN72423.1 - 0.098 12.5 11.5 0.46 10.4 1.2 3.5 3 0 0 3 3 3 0 IQ calmodulin-binding motif EF-hand_7 PF13499.6 RLN72423.1 - 0.46 11.0 2.8 34 5.0 0.0 4.6 3 1 1 4 4 4 0 EF-hand domain pair Glyco_trans_2_3 PF13632.6 RLN72424.1 - 9.3e-14 51.8 0.0 9.3e-14 51.8 0.0 3.2 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 RLN72424.1 - 6.7e-10 39.2 0.0 1.5e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cellulose_synt PF03552.14 RLN72424.1 - 6.8e-09 34.8 2.7 0.0023 16.5 0.4 3.5 3 1 1 4 4 4 2 Cellulose synthase PH PF00169.29 RLN72424.1 - 2.3e-08 34.5 0.1 5.4e-08 33.3 0.1 1.7 1 0 0 1 1 1 1 PH domain Glycos_transf_2 PF00535.26 RLN72424.1 - 5.4e-08 32.8 0.0 0.012 15.4 0.0 3.5 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 RLN72424.1 - 7.7e-06 25.5 0.0 0.0011 18.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 zf-C6H2 PF15801.5 RLN72424.1 - 0.0021 18.3 9.1 0.0021 18.3 9.1 2.5 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding PH_11 PF15413.6 RLN72424.1 - 0.0037 17.7 0.9 0.012 16.0 0.2 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 RLN72424.1 - 0.008 16.4 0.7 0.066 13.5 0.7 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain Abhydrolase_6 PF12697.7 RLN72427.1 - 5.7e-05 23.8 7.7 5.7e-05 23.8 7.7 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 RLN72427.1 - 0.072 13.2 0.1 0.21 11.6 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain Palm_thioest PF02089.15 RLN72427.1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Pkinase_Tyr PF07714.17 RLN72429.1 - 6.4e-09 35.5 0.1 2.4e-05 23.8 0.0 4.6 4 1 0 4 4 4 1 Protein tyrosine kinase Pkinase PF00069.25 RLN72429.1 - 5.3e-07 29.3 0.0 0.0069 15.8 0.0 3.7 3 1 0 3 3 3 2 Protein kinase domain V-SNARE_C PF12352.8 RLN72432.1 - 1.3e-11 44.6 7.0 4.5e-05 23.6 0.5 2.6 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 RLN72432.1 - 0.045 14.1 0.7 0.045 14.1 0.7 2.0 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus P21-Arc PF04062.14 RLN72432.1 - 0.12 12.4 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 ARP2/3 complex ARPC3 (21 kDa) subunit TACC_C PF05010.14 RLN72432.1 - 0.14 11.9 2.4 0.21 11.4 2.4 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PLAC9 PF15205.6 RLN72432.1 - 0.2 12.1 0.0 0.44 11.0 0.0 1.5 1 0 0 1 1 1 0 Placenta-specific protein 9 Sec20 PF03908.13 RLN72432.1 - 0.26 11.2 10.5 0.26 11.2 0.1 3.5 4 1 0 4 4 4 0 Sec20 Dict-STAT-coil PF09267.10 RLN72432.1 - 4 7.9 6.8 0.89 9.9 2.3 2.2 2 1 1 3 3 3 0 Dictyostelium STAT, coiled coil DDE_3 PF13358.6 RLN72435.1 - 0.00031 20.5 0.0 0.00044 20.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease FCD PF07729.12 RLN72435.1 - 0.033 14.6 0.2 0.059 13.8 0.2 1.4 1 0 0 1 1 1 0 FCD domain Mo25 PF08569.11 RLN72438.1 - 1.1e-75 255.0 1.7 1.5e-75 254.6 1.7 1.2 1 0 0 1 1 1 1 Mo25-like V-ATPase_H_N PF03224.14 RLN72438.1 - 0.012 14.9 4.8 0.029 13.7 0.6 2.1 1 1 0 2 2 2 0 V-ATPase subunit H PX PF00787.24 RLN72439.1 - 3.7e-09 36.6 0.6 6.5e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 PX domain Las1 PF04031.13 RLN72440.1 - 1e-45 155.6 7.8 2e-45 154.6 7.8 1.5 1 0 0 1 1 1 1 Las1-like AAA_2 PF07724.14 RLN72441.1 - 4.1e-41 140.9 0.3 5.8e-33 114.4 0.2 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 RLN72441.1 - 2.7e-16 60.2 0.6 2e-06 28.3 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 RLN72441.1 - 9e-09 35.3 2.2 1.6e-08 34.4 0.1 2.4 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 RLN72441.1 - 1.4e-07 31.6 0.4 4.8e-05 23.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RLN72441.1 - 8.9e-07 29.3 0.0 1.5e-05 25.2 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 RLN72441.1 - 8.1e-06 26.1 0.0 2.2e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain MCM PF00493.23 RLN72441.1 - 1.4e-05 24.3 0.3 0.00073 18.7 0.0 2.4 2 0 0 2 2 2 1 MCM P-loop domain RuvB_N PF05496.12 RLN72441.1 - 5.7e-05 22.9 0.4 0.023 14.4 0.0 3.2 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 RLN72441.1 - 6.5e-05 23.4 1.7 0.00035 21.0 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.21 RLN72441.1 - 0.00017 21.0 0.1 0.0028 17.1 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 RLN72441.1 - 0.0003 20.1 0.2 0.001 18.4 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin Sigma54_activat PF00158.26 RLN72441.1 - 0.00061 19.5 0.0 0.016 14.9 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain TIP49 PF06068.13 RLN72441.1 - 0.00085 18.6 0.1 0.00085 18.6 0.1 2.5 3 0 0 3 3 3 1 TIP49 P-loop domain G-alpha PF00503.20 RLN72441.1 - 0.00092 18.5 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_18 PF13238.6 RLN72441.1 - 0.00098 19.7 0.1 0.0041 17.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 RLN72441.1 - 0.001 19.1 0.1 1.9 8.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 RLN72441.1 - 0.0011 19.2 0.1 0.0049 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 RLN72441.1 - 0.0038 17.7 0.0 0.0097 16.4 0.0 1.8 1 1 0 1 1 1 1 ABC transporter Sigma54_activ_2 PF14532.6 RLN72441.1 - 0.0083 16.3 0.0 2.2 8.4 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Rad17 PF03215.15 RLN72441.1 - 0.0093 15.9 0.0 0.096 12.6 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain ATP-synt_ab PF00006.25 RLN72441.1 - 0.012 15.3 0.3 0.037 13.7 0.0 1.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain T2SSE PF00437.20 RLN72441.1 - 0.014 14.5 0.1 0.063 12.3 0.0 1.9 1 1 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 RLN72441.1 - 0.016 15.1 1.6 1.2 9.0 0.0 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 RLN72441.1 - 0.022 14.5 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 RLN72441.1 - 0.025 14.0 0.1 0.077 12.4 0.0 1.9 2 0 0 2 2 1 0 Bacterial TniB protein DEAD PF00270.29 RLN72441.1 - 0.036 13.8 0.0 0.15 11.8 0.0 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase NACHT PF05729.12 RLN72441.1 - 0.049 13.6 0.0 2.1 8.2 0.0 3.0 2 1 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 RLN72441.1 - 0.061 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 RLN72441.1 - 0.066 12.9 0.2 0.25 11.1 0.1 2.1 2 1 0 2 2 1 0 IstB-like ATP binding protein CPT PF07931.12 RLN72441.1 - 0.069 13.0 0.0 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein TsaE PF02367.17 RLN72441.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 RLN72441.1 - 0.084 12.5 0.2 0.41 10.3 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA-ATPase_like PF09820.9 RLN72441.1 - 0.11 11.9 0.3 2 7.7 0.0 2.6 3 0 0 3 3 3 0 Predicted AAA-ATPase RNA_helicase PF00910.22 RLN72441.1 - 0.14 12.5 0.0 0.79 10.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.6 RLN72441.1 - 0.47 10.9 4.8 14 6.1 0.1 3.6 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.6 RLN72441.1 - 0.93 9.8 3.7 0.97 9.8 1.1 2.4 2 1 0 2 2 2 0 AAA domain zf-C2H2_2 PF12756.7 RLN72442.1 - 8.2e-31 106.3 14.2 1.9e-25 89.2 5.0 3.3 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 RLN72442.1 - 6.5e-09 35.9 18.0 1.4e-08 34.8 1.8 4.2 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RLN72442.1 - 2.7e-07 30.7 2.5 2.7e-07 30.7 2.5 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type DUF629 PF04780.12 RLN72442.1 - 0.00033 19.3 6.6 0.012 14.2 0.4 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF629) OrsD PF12013.8 RLN72442.1 - 0.038 14.4 2.8 0.77 10.2 0.1 2.7 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-LYAR PF08790.11 RLN72442.1 - 0.26 11.2 6.6 0.62 10.0 0.1 3.0 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger LEM PF03020.15 RLN72442.1 - 0.41 10.2 3.1 0.72 9.5 0.2 2.5 3 0 0 3 3 3 0 LEM domain zf-3CxxC_2 PF17180.4 RLN72442.1 - 0.48 11.2 3.0 0.56 11.0 0.0 2.7 3 0 0 3 3 3 0 Zinc-binding domain Ribosomal_L29 PF00831.23 RLN72442.1 - 0.62 10.1 8.9 4.5 7.3 2.8 2.7 2 0 0 2 2 2 0 Ribosomal L29 protein zf-H2C2_2 PF13465.6 RLN72442.1 - 0.95 10.0 6.2 2.7 8.6 0.4 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 RLN72442.1 - 9.6 7.3 25.3 0.52 11.3 0.4 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger Rad60-SLD_2 PF13881.6 RLN72443.1 - 1.7e-13 50.6 0.0 2.5e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-RING_2 PF13639.6 RLN72444.1 - 2.9e-05 24.3 7.9 2.9e-05 24.3 7.9 2.1 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 RLN72444.1 - 0.00073 19.8 5.2 0.0018 18.5 5.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 RLN72444.1 - 0.0011 19.0 2.3 0.0025 17.8 2.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 RLN72444.1 - 0.005 16.9 5.1 0.005 16.9 5.1 2.0 2 0 0 2 2 2 1 RING-variant domain FANCL_C PF11793.8 RLN72444.1 - 0.0072 16.5 7.4 0.021 15.0 7.4 1.8 1 0 0 1 1 1 1 FANCL C-terminal domain C1_1 PF00130.22 RLN72444.1 - 0.021 14.7 2.3 0.026 14.4 1.2 1.8 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 RLN72444.1 - 0.021 14.4 2.5 0.052 13.2 2.5 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 RLN72444.1 - 0.027 14.8 5.9 0.094 13.0 5.9 2.0 1 0 0 1 1 1 0 RING-like domain zf-C3HC4 PF00097.25 RLN72444.1 - 0.029 14.3 9.8 0.062 13.2 9.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN72444.1 - 0.13 12.1 8.4 0.3 11.0 8.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 RLN72444.1 - 0.26 11.4 1.7 0.76 9.9 1.7 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 RLN72444.1 - 0.33 10.9 6.3 0.61 10.0 5.4 2.0 2 0 0 2 2 2 0 PHD-finger zf-C3HC4_3 PF13920.6 RLN72444.1 - 3.1 7.7 9.2 8.6 6.3 9.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN72444.1 - 9.6 6.3 9.2 3.8 7.6 5.9 2.1 1 1 1 2 2 2 0 RING-type zinc-finger SYS1 PF09801.9 RLN72445.1 - 4e-29 101.6 1.3 4.3e-29 101.5 1.3 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network F-box-like PF12937.7 RLN72446.1 - 0.00035 20.4 0.1 0.00094 19.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RLN72446.1 - 0.00037 20.3 0.1 0.0013 18.6 0.1 2.0 1 0 0 1 1 1 1 F-box domain Pkinase PF00069.25 RLN72446.1 - 0.00039 19.9 0.0 0.00066 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 RLN72446.1 - 0.19 11.1 0.0 0.19 11.1 0.0 2.7 3 1 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family CTD_bind PF04818.13 RLN72449.1 - 6.9e-12 46.0 0.1 1.3e-10 42.0 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase II-binding domain. F_actin_bind PF08919.10 RLN72449.1 - 0.038 14.1 0.0 0.092 12.8 0.0 1.6 1 0 0 1 1 1 0 F-actin binding TFIIA PF03153.13 RLN72452.1 - 0.059 13.4 12.1 0.074 13.0 12.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SRP-alpha_N PF04086.13 RLN72452.1 - 7.8 6.3 18.9 12 5.8 18.9 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF1279 PF06916.13 RLN72453.1 - 8.5e-10 39.1 0.0 1.5e-09 38.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) ASH PF15780.5 RLN72454.1 - 4.6e-67 222.3 36.7 2.4e-07 30.9 0.0 24.3 26 1 1 27 27 27 17 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 RLN72454.1 - 3.9e-22 78.2 9.4 0.21 11.4 0.0 16.5 19 0 0 19 19 19 5 MSP (Major sperm protein) domain PapD-like PF14874.6 RLN72454.1 - 3.4e-18 65.7 2.6 0.063 13.4 0.0 11.4 12 0 0 12 12 12 4 Flagellar-associated PapD-like DUF1573 PF07610.11 RLN72454.1 - 3.4e-16 59.0 9.4 0.093 12.8 0.0 13.9 16 1 0 16 16 16 3 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 RLN72454.1 - 1.3e-13 51.0 15.4 0.034 14.4 0.0 14.0 18 0 0 18 18 18 2 Transmembrane protein 131-like MYCBPAP PF14646.6 RLN72454.1 - 5.1e-10 38.9 5.8 0.0094 14.9 0.0 9.3 12 0 0 12 12 12 2 MYCBP-associated protein family Hydin_ADK PF17213.3 RLN72454.1 - 0.019 15.3 0.0 0.094 13.0 0.0 2.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 RLN72454.1 - 0.11 13.0 0.0 0.3 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain fn3_6 PF17766.1 RLN72454.1 - 9 6.6 11.1 3.8 7.7 0.0 6.0 9 0 0 9 9 9 0 Fibronectin type-III domain A_deaminase PF00962.22 RLN72456.1 - 7.4e-89 298.3 0.0 1e-88 297.9 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase SMC_N PF02463.19 RLN72457.1 - 1.3e-10 41.1 0.0 1.3e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 RLN72457.1 - 0.03 14.6 0.2 0.051 13.8 0.2 1.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit C2 PF00168.30 RLN72460.1 - 3e-12 46.7 0.0 5.3e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain FimA PF16970.5 RLN72460.1 - 0.088 13.0 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Type-1 fimbrial protein, A C2 PF00168.30 RLN72461.1 - 1.1e-12 48.2 0.0 1.9e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain IGPD PF00475.18 RLN72461.1 - 0.075 13.3 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Imidazoleglycerol-phosphate dehydratase MULE PF10551.9 RLN72463.1 - 3.9e-09 36.8 0.0 1.1e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain LRR_6 PF13516.6 RLN72464.1 - 3.4e-19 67.2 23.7 0.073 13.2 0.0 7.8 7 0 0 7 7 7 7 Leucine Rich repeat LRR_4 PF12799.7 RLN72464.1 - 1.4e-08 34.9 18.0 0.014 15.8 2.6 5.1 2 2 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN72464.1 - 8.7e-08 31.7 16.6 1 10.1 0.1 8.2 8 0 0 8 8 8 3 Leucine Rich Repeat DUF4476 PF14771.6 RLN72464.1 - 5.2e-05 23.5 0.7 0.021 15.1 0.1 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4476) LRR_8 PF13855.6 RLN72464.1 - 0.11 12.2 23.4 4.5 7.1 3.1 5.9 3 2 3 6 6 6 0 Leucine rich repeat BBS2_N PF14781.6 RLN72465.1 - 0.062 13.2 0.8 0.12 12.3 0.8 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal Calpain_inhib PF00748.19 RLN72465.1 - 0.45 11.0 5.6 0.24 11.9 1.8 2.1 2 0 0 2 2 2 0 Calpain inhibitor CspB_prodomain PF18425.1 RLN72469.1 - 0.045 13.7 0.0 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 Csp protease B prodomain NIP_1 PF08995.10 RLN72469.1 - 0.1 13.0 0.5 0.1 13.0 0.5 2.4 2 0 0 2 2 2 0 Necrosis inducing protein-1 DUF4173 PF13777.6 RLN72471.1 - 0.0013 18.2 3.7 0.0013 18.2 3.7 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4173) PRC PF05239.16 RLN72473.1 - 0.0042 17.1 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 PRC-barrel domain FANCA_interact PF15751.5 RLN72473.1 - 0.072 13.6 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 FAAP20 FANCA interaction domain FYVE_2 PF02318.16 RLN72473.1 - 0.97 9.7 6.3 2.3 8.5 6.3 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger GCFC PF07842.12 RLN72475.1 - 1.8e-64 218.0 3.1 2.5e-64 217.6 3.1 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 RLN72475.1 - 7.7e-07 28.9 1.7 1.8e-06 27.7 1.7 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 RLN72475.1 - 8.7e-05 22.5 0.7 8.7e-05 22.5 0.7 2.1 2 0 0 2 2 2 1 G-patch domain DUF16 PF01519.16 RLN72475.1 - 2.6 8.6 5.1 1.9 9.0 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 SH2_2 PF14633.6 RLN72476.1 - 4.4e-58 196.2 0.0 1.6e-57 194.4 0.0 2.0 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.6 RLN72476.1 - 6.9e-21 74.6 0.4 6.9e-21 74.6 0.4 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif HTH_44 PF14641.6 RLN72476.1 - 5.1e-12 46.2 0.1 1.3e-11 44.9 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 YqgF PF14639.6 RLN72476.1 - 1.2e-09 38.2 0.0 2.5e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 RLN72476.1 - 2.6e-07 31.1 33.0 2.6e-07 31.1 33.0 4.4 2 1 1 4 4 4 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 RLN72476.1 - 5e-07 30.5 1.3 3.1e-06 28.0 0.0 3.0 2 1 1 3 3 2 1 HHH domain Tex_YqgF PF16921.5 RLN72476.1 - 1.2e-06 29.0 0.0 9.1e-06 26.1 0.0 2.5 2 0 0 2 2 2 1 Tex protein YqgF-like domain SH2 PF00017.24 RLN72476.1 - 4.4e-05 23.5 0.0 0.0002 21.4 0.0 2.2 2 0 0 2 2 2 1 SH2 domain Tex_N PF09371.10 RLN72476.1 - 0.00011 21.9 0.3 0.0015 18.3 0.0 2.3 2 0 0 2 2 2 1 Tex-like protein N-terminal domain HHH_3 PF12836.7 RLN72476.1 - 0.0042 17.3 0.0 0.009 16.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Flag1_repress PF03614.13 RLN72476.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Repressor of phase-1 flagellin LCD1 PF09798.9 RLN72476.1 - 0.33 9.4 9.5 0.046 12.3 1.2 2.5 3 0 0 3 3 3 0 DNA damage checkpoint protein PI3_PI4_kinase PF00454.27 RLN72478.1 - 4.2e-48 164.4 0.0 1e-47 163.1 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase NUC194 PF08163.12 RLN72478.1 - 1.2e-44 152.8 0.1 7e-44 150.3 0.1 2.2 1 1 0 1 1 1 1 NUC194 domain FATC PF02260.20 RLN72478.1 - 3.3e-08 33.2 0.4 1.8e-07 30.8 0.1 2.3 2 0 0 2 2 2 1 FATC domain CNOT11 PF10155.9 RLN72478.1 - 0.18 12.0 0.8 0.99 9.6 0.0 2.7 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 RTC PF01137.21 RLN72479.1 - 6.8e-60 202.0 0.0 7.8e-60 201.8 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 RLN72479.1 - 7.3e-35 119.6 0.0 2.1e-34 118.1 0.0 1.8 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Orn_Arg_deC_N PF02784.16 RLN72480.1 - 6.6e-35 120.7 0.0 1.8e-34 119.3 0.0 1.8 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 RLN72480.1 - 2.8e-07 30.7 0.0 5e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain TIG PF01833.24 RLN72481.1 - 2e-11 43.8 1.3 1.7e-10 40.8 0.1 2.8 2 0 0 2 2 2 1 IPT/TIG domain Cadherin_4 PF17803.1 RLN72481.1 - 0.00085 19.9 2.9 0.92 10.2 0.1 2.8 2 0 0 2 2 2 2 Bacterial cadherin-like domain TIG_plexin PF17960.1 RLN72481.1 - 0.14 12.1 0.0 0.44 10.6 0.0 1.8 1 0 0 1 1 1 0 TIG domain TIG PF01833.24 RLN72482.1 - 3e-118 386.2 58.7 4.2e-14 52.4 0.1 19.2 18 1 1 19 19 19 15 IPT/TIG domain TIG_plexin PF17960.1 RLN72482.1 - 2.2e-30 104.5 7.4 1.1 9.3 0.0 16.2 16 1 0 16 16 16 11 TIG domain Ephrin_rec_like PF07699.13 RLN72482.1 - 8e-06 25.5 0.2 8e-06 25.5 0.2 8.9 11 2 2 13 13 13 4 Putative ephrin-receptor like bVLRF1 PF18826.1 RLN72483.1 - 5.5e-51 172.4 0.0 1.1e-50 171.3 0.0 1.6 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor CH_2 PF06294.11 RLN72483.1 - 8.6e-25 86.7 0.1 2e-22 79.1 0.1 2.5 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 RLN72483.1 - 7.9e-13 48.1 0.0 3.4e-12 46.0 0.0 2.0 2 0 0 2 2 2 1 CAMSAP CH domain VATC PF18716.1 RLN72483.1 - 1.6e-10 40.6 0.9 4.2e-10 39.3 0.9 1.7 1 0 0 1 1 1 1 Vms1-associating treble clef domain Ank_4 PF13637.6 RLN72483.1 - 2.4e-08 34.4 0.0 4.8e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN72483.1 - 0.0005 20.3 0.1 0.0012 19.1 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN72483.1 - 0.00064 20.3 0.1 0.0012 19.3 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN72483.1 - 0.0026 18.1 0.0 0.0072 16.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank PF00023.30 RLN72483.1 - 0.0031 17.9 1.1 0.011 16.2 1.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat DUF5308 PF17233.2 RLN72483.1 - 0.057 13.7 1.1 8.4 6.6 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5308) AP3D1 PF06375.11 RLN72483.1 - 0.16 12.2 10.4 0.045 14.0 2.9 2.5 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 CD52 PF15116.6 RLN72483.1 - 0.2 11.7 0.1 0.2 11.7 0.1 2.1 2 0 0 2 2 1 0 CAMPATH-1 antigen eIF3_subunit PF08597.10 RLN72483.1 - 0.34 10.8 21.5 0.4 10.5 1.0 2.4 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Eapp_C PF10238.9 RLN72483.1 - 0.75 9.9 9.5 0.48 10.5 4.4 2.9 3 0 0 3 3 3 0 E2F-associated phosphoprotein Pox_Ag35 PF03286.14 RLN72483.1 - 1.3 8.8 15.1 8.1 6.2 0.7 2.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein SR-25 PF10500.9 RLN72483.1 - 4.9 6.7 26.3 0.044 13.4 6.9 3.4 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein Ribosomal_L6e PF01159.19 RLN72483.1 - 5.5 7.6 8.3 1.9 9.1 3.1 2.5 2 0 0 2 2 2 0 Ribosomal protein L6e DUF641 PF04859.12 RLN72484.1 - 0.0094 16.3 0.8 0.013 15.8 0.8 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Spo12 PF05032.12 RLN72484.1 - 0.04 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Spo12 family XLF PF09302.11 RLN72484.1 - 0.13 12.4 0.6 0.18 11.9 0.6 1.3 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Arm PF00514.23 RLN72485.1 - 0.23 11.6 1.2 5.9 7.1 0.4 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DHHC PF01529.20 RLN72486.1 - 5.9e-32 110.6 8.3 5.9e-32 110.6 8.3 1.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase Glyco_hydro_43 PF04616.14 RLN72490.1 - 5.8e-35 121.0 3.6 7.9e-35 120.6 3.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 LRR_10 PF18805.1 RLN72490.1 - 0.15 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat Pec_lyase_C PF00544.19 RLN72491.1 - 7.4e-08 32.2 7.1 0.0001 22.0 1.1 2.5 2 1 1 3 3 3 2 Pectate lyase Tam41_Mmp37 PF09139.11 RLN72492.1 - 3.2e-89 299.6 0.1 5e-89 298.9 0.1 1.3 1 1 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Sec61_beta PF03911.16 RLN72493.1 - 1.2e-18 66.8 0.1 1.2e-18 66.8 0.1 2.3 2 0 0 2 2 2 1 Sec61beta family DUF2207 PF09972.9 RLN72493.1 - 0.068 11.9 0.0 0.093 11.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DNA_pol_phi PF04931.13 RLN72494.1 - 1.4e-86 291.3 43.0 1.4e-85 288.0 33.3 5.7 2 2 3 5 5 5 2 DNA polymerase phi Ran_BP1 PF00638.18 RLN72495.1 - 5.3e-13 49.3 0.2 1.1e-12 48.3 0.2 1.4 1 0 0 1 1 1 1 RanBP1 domain SCO1-SenC PF02630.14 RLN72495.1 - 5.4e-05 23.1 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 SCO1/SenC NUP50 PF08911.11 RLN72495.1 - 0.0038 17.9 6.7 0.0038 17.9 6.7 6.1 3 3 1 4 4 4 1 NUP50 (Nucleoporin 50 kDa) Glyco_hydro_43 PF04616.14 RLN72496.1 - 1.7e-32 112.9 1.0 2.5e-32 112.4 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_43 PF04616.14 RLN72497.1 - 3.9e-33 115.0 0.8 5.7e-33 114.5 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Nitroreductase PF00881.24 RLN72498.1 - 9.7e-28 97.3 0.2 3.6e-27 95.5 0.2 1.8 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 RLN72498.1 - 0.00049 19.7 0.0 1 8.9 0.0 2.6 2 1 0 2 2 2 2 Putative TM nitroreductase RICTOR_N PF14664.6 RLN72499.1 - 0.084 11.8 2.0 21 3.9 0.1 3.4 2 2 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term Fes1 PF08609.10 RLN72499.1 - 0.24 12.3 2.8 1.4 9.8 2.8 2.3 1 1 0 1 1 1 0 Nucleotide exchange factor Fes1 Complex1_LYR PF05347.15 RLN72500.1 - 0.00038 20.5 0.2 0.00065 19.7 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF4490 PF14892.6 RLN72501.1 - 0.0023 18.0 0.2 0.0051 16.9 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4490) Gaa1 PF04114.14 RLN72502.1 - 0.17 10.8 3.1 0.3 10.1 1.1 1.9 2 0 0 2 2 2 0 Gaa1-like, GPI transamidase component UPF0182 PF03699.13 RLN72502.1 - 0.51 8.4 2.9 0.71 7.9 2.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) CitMHS PF03600.16 RLN72502.1 - 0.86 8.7 9.2 1.5 8.0 9.2 1.3 1 0 0 1 1 1 0 Citrate transporter GPI2 PF06432.11 RLN72502.1 - 8 5.8 10.3 2.5 7.5 7.7 1.4 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Ank_4 PF13637.6 RLN72503.1 - 4.2e-22 78.2 0.6 5.4e-13 49.2 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN72503.1 - 9.6e-22 76.8 1.2 4.6e-08 33.2 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN72503.1 - 2.5e-20 72.8 0.0 3.9e-13 49.8 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 RLN72503.1 - 2.8e-19 68.6 0.1 1.1e-06 28.8 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 RLN72503.1 - 3.8e-17 60.6 0.2 3.4e-05 23.9 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat F-box-like PF12937.7 RLN72503.1 - 5.4e-07 29.4 0.0 1.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RLN72503.1 - 8.2e-05 22.4 0.3 0.00017 21.4 0.3 1.4 1 0 0 1 1 1 1 F-box domain SCO1-SenC PF02630.14 RLN72504.1 - 3.5e-44 150.0 0.0 4.5e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 RLN72504.1 - 0.0016 18.4 0.0 0.0024 17.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 RLN72504.1 - 0.0078 16.5 0.0 0.033 14.5 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like NatB_MDM20 PF09797.9 RLN72505.1 - 2e-60 204.8 11.1 2e-60 204.8 11.1 1.9 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 RLN72505.1 - 0.024 15.2 7.4 0.08 13.5 0.0 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_5 PF12688.7 RLN72505.1 - 0.47 10.7 6.2 2.7 8.2 0.1 4.0 4 0 0 4 4 4 0 Tetratrico peptide repeat TPR_2 PF07719.17 RLN72505.1 - 1.7 9.0 4.1 14 6.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Cep57_MT_bd PF06657.13 RLN72505.1 - 2.1 8.9 8.8 46 4.6 0.1 4.9 4 1 1 5 5 5 0 Centrosome microtubule-binding domain of Cep57 TPR_14 PF13428.6 RLN72505.1 - 3.3 8.8 7.1 4.7 8.3 0.0 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat T7SS_ESX_EspC PF10824.8 RLN72505.1 - 3.5 8.2 7.4 1 9.8 1.3 3.1 3 0 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm WD40 PF00400.32 RLN72506.1 - 4.3e-17 62.2 2.2 0.0013 19.5 0.0 6.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Ras PF00071.22 RLN72511.1 - 2.3e-54 183.3 2.1 9e-52 174.9 2.1 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RLN72511.1 - 3.8e-29 101.3 1.1 4.7e-18 65.6 0.1 2.8 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN72511.1 - 4.7e-12 45.7 0.5 3.6e-11 42.8 0.5 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RLN72511.1 - 4.1e-06 26.8 0.6 0.097 12.6 0.3 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 RLN72511.1 - 0.01 15.4 0.2 0.024 14.2 0.1 1.7 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 RLN72511.1 - 0.011 15.2 0.0 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 RLN72511.1 - 0.015 15.7 0.2 2.8 8.4 0.0 2.4 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 RLN72511.1 - 0.018 15.1 0.0 1.6 8.8 0.0 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 RLN72511.1 - 0.028 13.9 0.0 0.49 9.8 0.0 2.1 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 RLN72511.1 - 0.034 14.4 0.0 0.076 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RLN72511.1 - 0.04 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN72511.1 - 0.056 13.8 0.0 0.078 13.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 RLN72511.1 - 0.068 13.2 0.0 0.15 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) FeoB_N PF02421.18 RLN72511.1 - 0.12 11.9 0.0 0.99 8.9 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B Gtr1_RagA PF04670.12 RLN72511.1 - 0.17 11.2 0.9 10 5.4 0.0 2.2 1 1 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA PF00004.29 RLN72512.1 - 6.5e-17 62.2 0.0 1.4e-16 61.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 RLN72512.1 - 2.8e-13 50.0 0.0 5.3e-11 42.6 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 RLN72512.1 - 5.1e-11 42.8 0.0 1.4e-10 41.4 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA_16 PF13191.6 RLN72512.1 - 6.9e-06 26.5 0.0 0.00042 20.7 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 RLN72512.1 - 8.5e-06 25.6 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 RLN72512.1 - 1.8e-05 24.5 0.0 0.00014 21.6 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 RLN72512.1 - 2.5e-05 24.5 0.0 0.00015 22.0 0.0 2.1 2 0 0 2 2 2 1 AAA C-terminal domain AAA_22 PF13401.6 RLN72512.1 - 7.9e-05 23.0 0.8 0.018 15.3 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 RLN72512.1 - 0.00027 20.8 0.0 0.00099 19.0 0.0 1.7 1 1 1 2 2 2 1 AAA domain DNA_pol3_delta PF06144.13 RLN72512.1 - 0.00071 19.4 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 RLN72512.1 - 0.00082 18.8 0.0 0.06 12.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RLN72512.1 - 0.0019 18.1 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 RLN72512.1 - 0.005 16.9 0.0 0.014 15.4 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RLN72512.1 - 0.006 16.9 0.0 0.059 13.7 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 RLN72512.1 - 0.012 15.6 0.1 0.089 12.8 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 RLN72512.1 - 0.018 15.6 0.0 0.034 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 RLN72512.1 - 0.018 14.7 0.0 0.067 12.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 RLN72512.1 - 0.02 14.7 0.3 0.16 11.8 0.0 2.4 2 1 1 3 3 3 0 DEAD/DEAH box helicase Sigma54_activat PF00158.26 RLN72512.1 - 0.024 14.3 0.0 0.17 11.5 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 RLN72512.1 - 0.062 12.8 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 RLN72512.1 - 0.1 12.5 0.2 17 5.3 0.1 2.9 2 1 1 3 3 3 0 NTPase PhoH PF02562.16 RLN72512.1 - 0.11 11.9 0.1 4.5 6.7 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DUF5338 PF17273.2 RLN72512.1 - 0.13 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5338) AAA_23 PF13476.6 RLN72512.1 - 0.17 12.3 0.0 0.28 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 RLN72513.1 - 1.1e-14 54.5 12.8 2.6e-05 24.9 0.6 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN72513.1 - 3.8e-08 33.5 1.2 0.033 14.5 0.0 4.7 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Cyclin_N PF00134.23 RLN72514.1 - 1.9e-07 30.8 1.8 1.4e-05 24.8 0.0 2.4 1 1 1 2 2 2 2 Cyclin, N-terminal domain Lectin_leg-like PF03388.13 RLN72515.1 - 5.7e-32 110.9 0.1 8.5e-32 110.3 0.1 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 RLN72515.1 - 5.7e-12 46.1 1.5 5.7e-12 46.1 1.5 1.5 2 0 0 2 2 2 1 Bacterial lectin Lectin_legB PF00139.19 RLN72515.1 - 1.6e-08 34.4 0.1 5.3e-08 32.7 0.1 1.9 1 1 0 1 1 1 1 Legume lectin domain Ead_Ea22 PF13935.6 RLN72515.1 - 0.0014 19.3 5.6 0.76 10.4 2.5 2.4 1 1 1 2 2 2 2 Ead/Ea22-like protein Phage_tail_NK PF16532.5 RLN72515.1 - 0.1 12.2 0.2 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 Sf6-type phage tail needle knob or tip of some Caudovirales Grg1 PF11034.8 RLN72515.1 - 0.2 11.9 3.2 0.41 10.9 3.2 1.5 1 0 0 1 1 1 0 Glucose-repressible protein Grg1 His_Phos_2 PF00328.22 RLN72516.1 - 5.4e-15 55.6 0.1 5.3e-08 32.6 0.1 2.8 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF2373 PF10180.9 RLN72517.1 - 1e-11 44.5 1.6 3.1e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2373) DBP PF12361.8 RLN72517.1 - 0.048 13.5 2.2 0.069 13.0 2.2 1.2 1 0 0 1 1 1 0 Duffy-antigen binding protein Atg8 PF02991.16 RLN72518.1 - 8.9e-47 157.6 1.2 3.8e-46 155.5 1.2 1.7 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 RLN72518.1 - 6.1e-07 29.8 0.0 7.8e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 WD40 PF00400.32 RLN72519.1 - 1.5e-16 60.4 32.2 8.2e-07 29.6 0.2 11.5 12 0 0 12 12 12 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN72519.1 - 4e-08 33.5 0.2 2.5 8.5 0.0 6.0 5 0 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_7 PF13499.6 RLN72520.1 - 0.0011 19.4 2.6 0.037 14.5 0.6 2.9 2 0 0 2 2 2 1 EF-hand domain pair TPR_MLP1_2 PF07926.12 RLN72520.1 - 0.003 17.6 19.0 0.003 17.6 19.0 6.1 4 2 1 5 5 5 2 TPR/MLP1/MLP2-like protein EF-hand_6 PF13405.6 RLN72520.1 - 0.044 13.7 0.3 21 5.4 0.1 3.1 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 RLN72520.1 - 0.085 12.5 0.1 13 5.6 0.0 2.9 3 0 0 3 3 3 0 EF hand GMC_oxred_N PF00732.19 RLN72521.1 - 6.7e-101 337.6 0.0 1e-100 336.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 RLN72521.1 - 1.4e-39 135.9 0.0 2.5e-39 135.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 RLN72521.1 - 3e-08 33.2 0.0 0.0058 15.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 RLN72521.1 - 3.5e-06 26.3 0.0 5.2e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 RLN72521.1 - 2.7e-05 23.5 0.0 0.00036 19.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RLN72521.1 - 7.3e-05 22.5 0.4 0.00073 19.2 0.2 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RLN72521.1 - 0.00037 20.7 0.0 0.0013 18.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 RLN72521.1 - 0.00098 19.6 0.0 0.025 15.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RLN72521.1 - 0.0044 16.4 0.3 1.9 7.7 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 RLN72521.1 - 0.022 13.5 0.0 0.072 11.8 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 RLN72521.1 - 0.023 13.9 0.1 0.074 12.3 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 RLN72521.1 - 0.024 13.9 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 RLN72521.1 - 0.025 14.2 0.0 0.063 12.9 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 RLN72521.1 - 0.025 14.8 0.0 0.084 13.1 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Voltage_CLC PF00654.20 RLN72523.1 - 3.7e-54 184.3 32.5 5.3e-54 183.8 32.5 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 RLN72523.1 - 4.3e-06 27.1 0.4 0.014 15.8 0.1 2.6 2 0 0 2 2 2 2 CBS domain PDZ_6 PF17820.1 RLN72524.1 - 0.002 17.9 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RLN72524.1 - 0.0052 17.1 0.0 0.0078 16.5 0.0 1.3 1 0 0 1 1 1 1 PDZ domain zf-C4_Topoisom PF01396.19 RLN72524.1 - 2.5 7.9 4.4 0.31 10.9 0.3 1.6 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Voltage_CLC PF00654.20 RLN72525.1 - 1.2e-54 185.9 32.0 1.6e-54 185.5 32.0 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel DUF5408 PF17402.2 RLN72525.1 - 1.7 8.6 4.5 1.1 9.2 0.5 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5408) TIMELESS PF04821.14 RLN72526.1 - 4.1e-55 187.0 5.6 4.1e-55 187.0 5.6 2.0 2 0 0 2 2 2 1 Timeless protein SLIDE PF09111.10 RLN72526.1 - 0.061 13.3 0.4 0.56 10.2 0.2 2.6 2 0 0 2 2 2 0 SLIDE DUF5314 PF17241.2 RLN72526.1 - 0.067 12.9 1.0 0.24 11.0 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5314) ATP-synt_E PF05680.12 RLN72526.1 - 7.7 6.9 9.5 4.8 7.6 0.2 3.9 3 0 0 3 3 3 0 ATP synthase E chain DENN PF02141.21 RLN72527.1 - 1e-28 100.6 1.8 2.4e-28 99.4 1.8 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain RGS PF00615.19 RLN72527.1 - 3.1e-15 56.5 9.7 3.7e-07 30.4 1.4 2.9 2 0 0 2 2 2 2 Regulator of G protein signaling domain dDENN PF03455.19 RLN72527.1 - 0.0005 20.0 0.2 0.0024 17.8 0.1 2.3 2 0 0 2 2 2 1 dDENN domain DUF4444 PF14563.6 RLN72527.1 - 0.14 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4444) Complex1_LYR_2 PF13233.6 RLN72528.1 - 1.2e-16 61.2 1.4 1.4e-16 61.0 1.4 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 RLN72528.1 - 1.1e-06 28.6 0.6 2.3e-06 27.5 0.6 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF3719 PF12516.8 RLN72528.1 - 0.15 11.8 0.0 0.2 11.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3719) Nucleoporin_N PF08801.11 RLN72532.1 - 4.8e-49 167.3 0.0 1.8e-48 165.4 0.0 1.9 1 1 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 RLN72532.1 - 3.6e-07 29.3 1.4 6.7e-07 28.4 1.4 1.3 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal AAA_16 PF13191.6 RLN72533.1 - 7e-05 23.3 0.1 0.0002 21.8 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 RLN72533.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.5 1 1 1 2 2 2 0 IstB-like ATP binding protein Torsin PF06309.11 RLN72533.1 - 0.029 14.5 0.0 0.056 13.5 0.0 1.4 1 1 0 1 1 1 0 Torsin AAA_22 PF13401.6 RLN72533.1 - 0.058 13.7 0.0 0.17 12.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 RLN72533.1 - 0.061 13.0 0.0 0.075 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RLN72533.1 - 0.11 13.1 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF1713 PF08213.11 RLN72534.1 - 7.2e-08 32.2 19.1 1.1e-07 31.7 19.1 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) B9-C2 PF07162.11 RLN72535.1 - 2.9e-45 154.5 0.1 4.3e-45 153.9 0.1 1.3 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Macoilin PF09726.9 RLN72535.1 - 1.7 7.1 7.5 2.2 6.7 7.5 1.1 1 0 0 1 1 1 0 Macoilin family ArfGap PF01412.18 RLN72536.1 - 1e-34 119.1 0.0 1.9e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf C2 PF00168.30 RLN72536.1 - 1.9e-15 57.0 0.0 4.4e-15 55.8 0.0 1.7 2 0 0 2 2 2 1 C2 domain ATG_C PF09333.11 RLN72536.1 - 0.0009 19.5 0.0 0.0037 17.6 0.0 1.9 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain EF-hand_7 PF13499.6 RLN72537.1 - 0.0044 17.4 0.4 0.014 15.8 0.4 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN72537.1 - 0.17 11.9 1.6 0.29 11.2 0.1 2.1 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 RLN72537.1 - 1.1 8.9 0.0 1.1 8.9 0.0 2.7 3 0 0 3 3 3 0 EF hand Peptidase_C1 PF00112.23 RLN72539.1 - 3.8e-67 226.6 5.9 5.5e-67 226.0 5.9 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 RLN72539.1 - 3.1e-11 43.5 0.2 5.3e-11 42.8 0.2 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 RLN72539.1 - 5.7e-07 28.7 0.6 0.0028 16.5 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Glu_synthase PF01645.17 RLN72540.1 - 1.3e-152 508.3 0.1 5.8e-150 499.5 0.0 2.2 2 0 0 2 2 2 2 Conserved region in glutamate synthase Glu_syn_central PF04898.14 RLN72540.1 - 1.9e-105 352.3 0.0 3.4e-105 351.5 0.0 1.4 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.19 RLN72540.1 - 2.3e-76 255.7 5.4 4.6e-76 254.7 5.4 1.5 1 0 0 1 1 1 1 GXGXG motif AAA_9 PF12781.7 RLN72540.1 - 0.03 13.4 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 ATP-binding dynein motor region FMN_dh PF01070.18 RLN72540.1 - 0.054 12.5 0.1 0.98 8.4 0.1 2.5 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Rrp15p PF07890.12 RLN72541.1 - 2.8e-08 34.2 5.0 2.8e-08 34.2 5.0 2.0 2 0 0 2 2 2 1 Rrp15p Nop53 PF07767.11 RLN72541.1 - 0.067 12.6 17.3 0.084 12.3 17.3 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) BUD22 PF09073.10 RLN72541.1 - 2.8 7.2 21.2 3.6 6.8 21.2 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 RLN72541.1 - 3 6.0 19.8 3.7 5.6 19.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RLN72541.1 - 5.5 5.2 16.9 6.8 4.9 16.9 1.1 1 0 0 1 1 1 0 CDC45-like protein TMEM18 PF14770.6 RLN72544.1 - 3.4e-31 107.7 3.0 4.3e-31 107.4 3.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 DUF2206 PF09971.9 RLN72544.1 - 0.031 13.1 0.3 0.035 12.9 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) NAPRTase_C PF17956.1 RLN72545.1 - 1.2e-30 106.2 0.0 1.6e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain DEAD PF00270.29 RLN72546.1 - 1.2e-48 165.2 0.0 1.7e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 RLN72546.1 - 2.4e-06 27.7 0.0 3.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RLN72546.1 - 0.11 12.8 0.0 0.4 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain LSM PF01423.22 RLN72547.1 - 1.5e-18 66.2 0.0 1.7e-18 66.0 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RLN72547.1 - 3e-05 24.1 0.0 3.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Beach PF02138.18 RLN72548.1 - 8.2e-108 360.0 0.0 1.4e-107 359.2 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 RLN72548.1 - 2.6e-09 37.1 0.0 6.8e-07 29.3 0.0 3.2 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.32 RLN72548.1 - 1.8e-06 28.6 6.2 0.21 12.5 1.4 3.9 2 1 1 3 3 3 2 WD domain, G-beta repeat GRAM PF02893.20 RLN72548.1 - 0.0024 17.7 0.0 0.0059 16.5 0.0 1.6 1 0 0 1 1 1 1 GRAM domain PH_TFIIH PF08567.11 RLN72548.1 - 0.063 13.6 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain ANAPC4_WD40 PF12894.7 RLN72548.1 - 0.13 12.6 0.0 21 5.5 0.0 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TRAPP PF04051.16 RLN72549.1 - 7.2e-34 116.6 0.0 8e-34 116.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF3453 PF11935.8 RLN72553.1 - 1.3e-10 41.3 0.0 2.5e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) GHMP_kinases_N PF00288.26 RLN72553.1 - 0.36 11.1 5.9 0.26 11.5 3.1 2.2 2 0 0 2 2 2 0 GHMP kinases N terminal domain MFS_1 PF07690.16 RLN72554.1 - 2.9e-34 118.6 28.0 5.3e-34 117.7 28.0 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 RLN72554.1 - 2.1e-26 92.3 19.3 2.3e-20 72.4 1.0 3.2 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 RLN72554.1 - 2.9e-19 69.3 20.1 5.7e-19 68.3 20.1 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 RLN72554.1 - 3e-05 23.5 2.8 3e-05 23.5 2.8 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF2530 PF10745.9 RLN72554.1 - 4.1 7.7 13.4 0.41 10.9 1.4 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Actin PF00022.19 RLN72555.1 - 4.4e-128 427.4 0.0 1.7e-127 425.4 0.0 1.7 1 1 0 1 1 1 1 Actin PD40 PF07676.12 RLN72555.1 - 0.076 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat IQ PF00612.27 RLN72556.1 - 0.012 15.4 24.7 0.07 13.0 1.2 5.6 4 1 1 5 5 5 0 IQ calmodulin-binding motif zf-SNAP50_C PF12251.8 RLN72556.1 - 0.023 14.3 0.7 0.055 13.2 0.7 1.5 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal Rad1 PF02144.16 RLN72557.1 - 6.5e-44 150.1 0.1 9.7e-44 149.5 0.1 1.3 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 COG5 PF10392.9 RLN72558.1 - 2.5e-13 50.4 0.9 2.5e-13 50.4 0.9 2.2 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 RLN72558.1 - 2.4e-05 24.2 1.0 7.8e-05 22.6 1.0 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Zw10 PF06248.13 RLN72558.1 - 0.0015 17.2 0.5 0.0029 16.2 0.5 1.5 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 YscO PF07321.12 RLN72558.1 - 0.0041 17.1 0.7 0.017 15.1 0.7 2.0 1 0 0 1 1 1 1 Type III secretion protein YscO Hrs_helical PF12210.8 RLN72558.1 - 0.02 15.4 3.4 0.021 15.3 1.3 2.2 2 0 0 2 2 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Fib_alpha PF08702.10 RLN72558.1 - 0.02 15.1 0.3 0.055 13.6 0.3 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family COG2 PF06148.11 RLN72558.1 - 0.039 14.0 2.9 0.094 12.8 1.7 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 BLOC1_2 PF10046.9 RLN72558.1 - 0.081 13.2 0.3 1 9.7 0.0 3.0 4 1 0 4 4 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FUSC PF04632.12 RLN72558.1 - 0.11 11.0 10.5 0.29 9.6 10.3 1.8 1 1 0 1 1 1 0 Fusaric acid resistance protein family Cob_adeno_trans PF01923.18 RLN72558.1 - 0.17 12.0 1.3 0.81 9.8 1.1 2.4 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Syntaxin-6_N PF09177.11 RLN72558.1 - 0.4 11.3 3.7 1.5 9.4 0.9 2.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal HsbA PF12296.8 RLN72558.1 - 0.48 10.9 3.5 12 6.3 0.2 3.4 3 0 0 3 3 3 0 Hydrophobic surface binding protein A NPV_P10 PF05531.12 RLN72558.1 - 0.59 10.6 1.8 5.6 7.5 0.5 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 RLN72558.1 - 4.1 8.1 6.8 7.3 7.3 2.1 3.5 2 1 1 3 3 3 0 SlyX Myosin_head PF00063.21 RLN72559.1 - 1.5e-224 747.1 3.0 2.6e-224 746.4 3.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) WW PF00397.26 RLN72559.1 - 2.3e-09 37.2 0.1 4.3e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 WW domain Tcell_CD4_C PF12104.8 RLN72559.1 - 0.0084 16.0 2.0 0.25 11.3 1.4 2.8 2 0 0 2 2 2 1 T cell CD4 receptor C terminal region G_glu_transpept PF01019.21 RLN72559.1 - 0.011 14.5 1.0 0.02 13.7 1.0 1.3 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase ProQ PF04352.13 RLN72559.1 - 0.011 15.6 0.0 0.049 13.5 0.0 2.1 1 0 0 1 1 1 0 ProQ/FINO family Rootletin PF15035.6 RLN72559.1 - 0.018 15.1 15.6 0.05 13.6 15.6 1.8 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion AAA_22 PF13401.6 RLN72559.1 - 0.02 15.2 0.1 0.2 11.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RLN72559.1 - 0.064 13.8 0.1 0.36 11.4 0.1 2.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RLN72559.1 - 0.068 13.6 0.0 0.39 11.1 0.0 2.4 1 0 0 1 1 1 0 AAA ATPase domain DUF1456 PF07308.13 RLN72559.1 - 0.13 12.6 0.6 0.6 10.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) FAM76 PF16046.5 RLN72559.1 - 0.22 10.8 11.9 0.49 9.7 11.9 1.5 1 0 0 1 1 1 0 FAM76 protein ZapB PF06005.12 RLN72559.1 - 1.4 9.4 12.8 4.5 7.8 3.5 3.4 2 0 0 2 2 2 0 Cell division protein ZapB ABC_tran PF00005.27 RLN72559.1 - 2.9 8.4 4.6 1.1 9.8 0.0 2.7 2 1 0 2 2 1 0 ABC transporter WW PF00397.26 RLN72560.1 - 4.6e-08 33.0 1.3 8.7e-08 32.1 1.3 1.4 1 0 0 1 1 1 1 WW domain ERp29 PF07749.12 RLN72560.1 - 0.078 13.9 0.0 0.27 12.1 0.0 1.8 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Lyase_aromatic PF00221.19 RLN72562.1 - 1.8e-187 623.7 3.6 3.4e-187 622.8 3.6 1.4 1 1 0 1 1 1 1 Aromatic amino acid lyase DUF3458_C PF17432.2 RLN72563.1 - 2.4e-23 83.1 0.2 4.5e-23 82.1 0.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats TMPIT PF07851.13 RLN72564.1 - 0.034 13.4 1.0 0.053 12.8 1.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF3573 PF12097.8 RLN72564.1 - 0.2 10.4 0.3 0.28 9.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DivIC PF04977.15 RLN72564.1 - 2.4 8.0 9.0 5.8 6.8 1.3 2.4 2 0 0 2 2 2 0 Septum formation initiator vATP-synt_E PF01991.18 RLN72564.1 - 2.6 7.4 7.6 0.26 10.7 1.8 1.9 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit LBR_tudor PF09465.10 RLN72565.1 - 0.09 12.6 0.2 0.85 9.5 0.1 2.3 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain CD20 PF04103.15 RLN72566.1 - 0.18 11.9 0.1 0.36 10.9 0.1 1.4 1 0 0 1 1 1 0 CD20-like family Menin PF05053.13 RLN72566.1 - 6.6 5.0 21.4 0.8 8.0 13.2 1.9 1 1 1 2 2 2 0 Menin SKN1 PF03935.15 RLN72568.1 - 3.5e-56 190.7 20.0 1.2e-20 73.5 0.4 4.9 3 2 0 3 3 3 3 Beta-glucan synthesis-associated protein (SKN1) Nodulin_late PF07127.11 RLN72568.1 - 0.46 10.8 2.7 0.98 9.8 0.9 2.4 2 0 0 2 2 2 0 Late nodulin protein EB PF01683.18 RLN72568.1 - 7.6 6.9 14.9 0.11 12.8 3.4 3.3 4 0 0 4 4 4 0 EB module HALZ PF02183.18 RLN72569.1 - 0.0017 18.5 0.7 0.0017 18.5 0.7 7.5 8 1 1 9 9 9 2 Homeobox associated leucine zipper APG6_N PF17675.1 RLN72569.1 - 0.0042 17.6 6.8 0.0042 17.6 6.8 7.2 2 1 4 6 6 6 1 Apg6 coiled-coil region Elong_Iki1 PF10483.9 RLN72573.1 - 3e-05 23.7 0.1 3.1e-05 23.6 0.1 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 PX PF00787.24 RLN72575.1 - 6.2e-12 45.5 4.0 1.2e-05 25.2 0.2 2.3 2 0 0 2 2 2 2 PX domain zf-C4H2 PF10146.9 RLN72576.1 - 0.016 15.5 0.3 0.034 14.4 0.3 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein DUF1918 PF08940.11 RLN72576.1 - 0.1 12.2 0.1 0.31 10.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Ge1_WD40 PF16529.5 RLN72577.1 - 5e-14 52.0 0.0 2.3e-07 30.1 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 RLN72577.1 - 2e-05 25.3 0.4 0.12 13.3 0.1 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Ints3 PF10189.9 RLN72577.1 - 0.14 11.4 0.3 3 7.1 0.0 2.3 1 1 1 2 2 2 0 Integrator complex subunit 3 LPP PF04728.13 RLN72577.1 - 0.2 12.0 0.8 0.93 9.9 0.8 2.2 1 0 0 1 1 1 0 Lipoprotein leucine-zipper DASH_Dad2 PF08654.10 RLN72577.1 - 0.29 11.6 1.9 0.64 10.5 0.2 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad2 Mer2 PF09074.10 RLN72577.1 - 0.3 10.9 4.8 0.96 9.2 4.6 2.0 1 1 0 1 1 1 0 Mer2 EcsC PF12787.7 RLN72577.1 - 0.74 9.4 3.3 1.7 8.2 0.1 2.3 1 1 1 2 2 2 0 EcsC protein family Spore_III_AB PF09548.10 RLN72577.1 - 0.82 9.8 3.7 1.4 9.0 0.1 2.7 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Kinesin PF00225.23 RLN72583.1 - 2.6e-36 125.2 0.0 3.7e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN72583.1 - 9.6e-19 67.8 0.0 2.2e-18 66.6 0.0 1.6 2 0 0 2 2 2 1 Microtubule binding E1-E2_ATPase PF00122.20 RLN72585.1 - 4.3e-14 52.4 0.0 6.3e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 E1-E2 ATPase Pkinase_Tyr PF07714.17 RLN72587.1 - 1.1e-51 175.6 0.0 1.1e-40 139.6 0.0 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN72587.1 - 1.1e-50 172.5 0.0 5.7e-39 134.1 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Ank_2 PF12796.7 RLN72587.1 - 4.2e-48 161.9 4.6 1.1e-17 64.3 0.3 5.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN72587.1 - 2.9e-37 126.6 0.1 1.5e-08 35.0 0.0 5.8 3 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN72587.1 - 5.4e-33 112.6 6.4 2.6e-07 30.8 0.1 7.6 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 RLN72587.1 - 2.6e-31 106.7 10.6 0.00025 21.3 0.0 8.5 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 RLN72587.1 - 3e-28 94.7 0.5 0.059 13.9 0.0 9.0 8 0 0 8 8 8 7 Ankyrin repeat Pkinase_fungal PF17667.1 RLN72587.1 - 0.00051 18.9 0.0 0.0016 17.3 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase SIP PF04954.13 RLN72587.1 - 0.0088 16.6 1.4 7.6 7.1 0.1 4.2 2 1 1 3 3 3 1 Siderophore-interacting protein RIO1 PF01163.22 RLN72587.1 - 0.061 12.9 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 RLN72587.1 - 0.063 13.2 1.5 0.091 12.7 0.1 2.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family UBA PF00627.31 RLN72587.1 - 0.37 10.7 4.5 4.5 7.3 0.2 3.6 3 0 0 3 3 3 0 UBA/TS-N domain NmrA PF05368.13 RLN72593.1 - 1.7e-13 50.7 0.0 1.8e-05 24.4 0.0 3.1 1 1 2 3 3 3 3 NmrA-like family bZIP_2 PF07716.15 RLN72595.1 - 0.082 13.0 11.8 0.17 12.0 11.8 1.4 1 0 0 1 1 1 0 Basic region leucine zipper UVR PF02151.19 RLN72596.1 - 6.2e-05 22.6 1.7 6.2e-05 22.6 1.7 2.1 2 0 0 2 2 2 1 UvrB/uvrC motif zf-Di19 PF05605.12 RLN72596.1 - 0.0015 18.8 10.5 1.2 9.5 0.1 3.3 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 RLN72596.1 - 0.19 11.4 8.2 0.5 10.0 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger TF_Zn_Ribbon PF08271.12 RLN72596.1 - 0.21 11.2 8.4 0.19 11.3 0.3 3.4 3 0 0 3 3 3 0 TFIIB zinc-binding zf-C2H2_4 PF13894.6 RLN72596.1 - 1.5 9.8 7.5 62 4.8 0.1 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger PDZ_6 PF17820.1 RLN72597.1 - 3.8e-18 65.1 0.4 0.00011 21.9 0.0 6.1 6 0 0 6 6 6 4 PDZ domain Bromodomain PF00439.25 RLN72597.1 - 7.7e-16 57.9 0.1 1.7e-15 56.9 0.1 1.6 1 0 0 1 1 1 1 Bromodomain PDZ PF00595.24 RLN72597.1 - 2.2e-11 43.9 0.3 0.29 11.5 0.1 6.3 6 1 0 6 6 6 3 PDZ domain FYRC PF05965.14 RLN72597.1 - 0.00023 21.3 0.0 0.0017 18.4 0.0 2.5 2 0 0 2 2 2 1 F/Y rich C-terminus DDT PF02791.17 RLN72597.1 - 0.00038 20.7 1.3 0.0014 18.9 1.3 2.1 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 RLN72597.1 - 0.00048 19.6 0.1 0.0012 18.3 0.1 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Sugar_tr PF00083.24 RLN72598.1 - 4e-42 144.6 25.6 9.5e-40 136.8 25.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN72598.1 - 2.4e-33 115.5 40.8 1.9e-28 99.4 19.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Mitofilin PF09731.9 RLN72613.1 - 5.9 5.6 8.8 6.3 5.5 8.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CBM_1 PF00734.18 RLN72622.1 - 0.1 12.6 0.5 0.21 11.6 0.5 1.5 1 0 0 1 1 1 0 Fungal cellulose binding domain CBM_1 PF00734.18 RLN72623.1 - 1.5e-07 31.2 0.8 2.4e-07 30.6 0.8 1.3 1 0 0 1 1 1 1 Fungal cellulose binding domain Alpha_GJ PF03229.13 RLN72623.1 - 0.031 14.8 1.4 0.046 14.3 1.4 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J Cluap1 PF10234.9 RLN72624.1 - 1.8 7.9 12.8 0.21 10.9 7.6 1.8 2 0 0 2 2 2 0 Clusterin-associated protein-1 Acetyltransf_6 PF13480.7 RLN72624.1 - 10 6.3 9.7 19 5.4 5.8 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain TMEM154 PF15102.6 RLN72626.1 - 0.018 14.9 0.1 0.018 14.9 0.1 2.3 2 1 0 2 2 2 0 TMEM154 protein family Peptidase_M56 PF05569.11 RLN72626.1 - 0.26 10.5 0.0 0.48 9.6 0.0 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 Ndc1_Nup PF09531.10 RLN72626.1 - 0.64 8.6 3.1 0.77 8.4 3.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hamartin PF04388.12 RLN72626.1 - 1.5 7.4 6.1 1.8 7.2 6.1 1.0 1 0 0 1 1 1 0 Hamartin protein GREB1 PF15782.5 RLN72626.1 - 4.7 4.2 6.5 5.4 4.0 6.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CBM_1 PF00734.18 RLN72627.1 - 2e-06 27.6 0.5 2.9e-06 27.1 0.5 1.2 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF2125 PF09898.9 RLN72627.1 - 0.025 14.2 0.3 0.031 13.9 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2125) RRM_1 PF00076.22 RLN72628.1 - 3e-13 49.4 0.0 1.3e-07 31.3 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.11 RLN72628.1 - 0.0048 16.4 0.5 0.021 14.3 0.0 2.3 2 0 0 2 2 2 1 Lsm interaction motif RRM_5 PF13893.6 RLN72628.1 - 0.055 13.1 0.1 4.6 6.8 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HBM PF16591.5 RLN72629.1 - 0.0017 17.8 0.0 0.0019 17.7 0.0 1.0 1 0 0 1 1 1 1 Helical bimodular sensor domain LptF_LptG PF03739.14 RLN72629.1 - 0.042 12.7 0.1 0.044 12.6 0.1 1.0 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG RSN1_7TM PF02714.15 RLN72630.1 - 2.9e-09 36.7 5.7 2.9e-09 36.7 5.7 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 RLN72630.1 - 0.0033 17.7 2.4 0.0033 17.7 2.4 2.4 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 RLN72630.1 - 0.043 12.7 0.1 0.043 12.7 0.1 2.1 3 0 0 3 3 3 0 Calcium-activated chloride channel Wtap PF17098.5 RLN72630.1 - 0.089 12.7 5.1 0.16 11.9 5.1 1.3 1 0 0 1 1 1 0 WTAP/Mum2p family Nic96 PF04097.14 RLN72634.1 - 2.2e-122 409.6 0.0 2.9e-122 409.2 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 HHH_8 PF14716.6 RLN72636.1 - 1.4e-09 38.1 0.0 3.5e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain ALS2CR8 PF15299.6 RLN72636.1 - 0.0054 16.7 0.6 0.0076 16.2 0.5 1.3 1 1 0 1 1 1 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 EF-hand_8 PF13833.6 RLN72637.1 - 0.014 15.2 0.1 0.16 11.8 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.32 RLN72637.1 - 0.03 13.9 0.0 0.67 9.6 0.0 2.7 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 RLN72637.1 - 0.13 11.8 0.6 0.48 10.0 0.0 2.3 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 RLN72637.1 - 0.16 12.5 0.2 1.5 9.3 0.1 2.7 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 RLN72637.1 - 0.17 11.9 0.0 1.3 9.1 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain Dscam_C PF12355.8 RLN72637.1 - 8.1 7.4 9.1 0.65 11.0 1.9 3.0 2 1 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal Ank_2 PF12796.7 RLN72640.1 - 2.8e-100 329.1 14.2 5.7e-19 68.5 0.2 7.2 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 RLN72640.1 - 9.9e-83 269.3 19.7 1.6e-06 28.3 0.0 13.9 14 0 0 14 14 14 13 Ankyrin repeat Ank_3 PF13606.6 RLN72640.1 - 1e-80 255.9 16.2 8.9e-07 28.8 0.0 14.0 14 0 0 14 14 14 13 Ankyrin repeat Ank_4 PF13637.6 RLN72640.1 - 4.5e-73 240.8 22.0 5.5e-10 39.6 0.1 11.7 2 2 8 12 12 12 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN72640.1 - 1.2e-70 232.6 32.7 7e-09 35.8 0.3 12.1 1 1 12 13 13 13 13 Ankyrin repeats (many copies) YfmQ PF10787.9 RLN72640.1 - 0.00052 19.8 0.0 42 3.9 0.0 6.0 3 2 3 7 7 7 0 Uncharacterised protein from bacillus cereus group DUF2390 PF09523.10 RLN72640.1 - 0.001 19.4 3.4 14 6.1 0.0 4.8 2 1 1 4 4 4 0 Protein of unknown function (DUF2390) Nepo_coat_C PF03688.14 RLN72640.1 - 0.0016 18.3 3.4 4 7.3 0.1 4.9 2 1 3 6 6 6 1 Nepovirus coat protein, C-terminal domain YlzJ PF14035.6 RLN72640.1 - 0.0037 17.4 0.0 1.2e+02 2.9 0.0 5.3 6 0 0 6 6 6 0 YlzJ-like protein MEDS PF14417.6 RLN72640.1 - 0.0052 16.6 1.9 10 5.9 0.0 4.0 2 1 2 4 4 4 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain tRNA_NucTran2_2 PF13735.6 RLN72640.1 - 0.0054 16.7 0.9 3.5 7.6 0.0 3.2 2 1 0 2 2 2 2 tRNA nucleotidyltransferase domain 2 putative Imm_superinfect PF14373.6 RLN72640.1 - 0.013 15.4 12.4 10 6.1 0.0 8.2 9 0 0 9 9 9 0 Superinfection immunity protein VWA_3_C PF18571.1 RLN72640.1 - 0.031 14.1 7.8 95 3.0 0.0 7.0 8 0 0 8 8 8 0 von Willebrand factor type A C-terminal domain SBP_bac_3 PF00497.20 RLN72640.1 - 0.4 10.1 3.4 38 3.6 0.1 4.4 4 2 0 4 4 4 0 Bacterial extracellular solute-binding proteins, family 3 Aa_trans PF01490.18 RLN72642.1 - 2.8e-45 154.8 16.9 3.3e-45 154.5 16.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ABC2_membrane_5 PF13346.6 RLN72642.1 - 0.38 10.3 11.5 0.094 12.3 3.2 2.6 2 0 0 2 2 2 0 ABC-2 family transporter protein Ank_2 PF12796.7 RLN72643.1 - 4.1e-14 52.9 0.1 2.6e-07 31.1 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN72643.1 - 7.5e-14 51.6 0.5 0.00098 19.4 0.0 3.7 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN72643.1 - 3.4e-11 42.3 0.3 0.057 14.0 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 RLN72643.1 - 3.9e-10 39.7 1.8 0.021 15.2 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 RLN72643.1 - 1.8e-09 37.9 0.1 0.0067 17.0 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) FYVE PF01363.21 RLN72643.1 - 0.0002 21.4 7.9 0.00043 20.4 7.9 1.5 1 1 0 1 1 1 1 FYVE zinc finger Prok-RING_2 PF14445.6 RLN72643.1 - 0.001 19.2 2.2 0.0025 17.9 2.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 2 DUF4428 PF14471.6 RLN72643.1 - 0.019 14.8 3.9 0.057 13.4 3.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) FYVE_2 PF02318.16 RLN72643.1 - 0.04 14.1 4.0 0.078 13.2 4.0 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Sar8_2 PF03058.14 RLN72643.1 - 0.96 10.0 4.9 44 4.7 4.9 2.7 1 1 0 1 1 1 0 Sar8.2 family KNOX1 PF03790.13 RLN72645.1 - 0.037 13.7 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 KNOX1 domain SWIRM-assoc_2 PF16496.5 RLN72646.1 - 0.058 12.3 1.6 0.074 11.9 1.6 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal HHH PF00633.23 RLN72646.1 - 0.21 11.5 0.6 2.5 8.1 0.2 2.8 1 1 1 2 2 2 0 Helix-hairpin-helix motif LRAT PF04970.13 RLN72647.1 - 3.1e-06 27.5 0.0 9.9e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 Lecithin retinol acyltransferase Ank_2 PF12796.7 RLN72648.1 - 6.6e-15 55.5 0.6 2.9e-12 47.0 0.3 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN72648.1 - 3.7e-14 52.6 1.5 5.3e-07 29.8 0.1 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN72648.1 - 1.3e-09 37.5 0.8 0.0083 16.6 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 RLN72648.1 - 1.2e-08 35.3 2.2 0.0014 19.2 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN72648.1 - 1.7e-06 28.2 0.9 0.012 16.1 0.0 4.1 4 1 0 4 4 4 1 Ankyrin repeat CDC45 PF02724.14 RLN72649.1 - 0.029 12.7 0.0 0.029 12.7 0.0 2.2 2 0 0 2 2 2 0 CDC45-like protein MCU PF04678.13 RLN72650.1 - 0.61 10.2 23.8 0.65 10.1 4.3 2.6 2 1 0 2 2 2 0 Mitochondrial calcium uniporter DUF1664 PF07889.12 RLN72650.1 - 3 7.9 15.1 0.3 11.1 4.3 3.4 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Prominin PF05478.11 RLN72650.1 - 5.3 4.9 10.9 0.71 7.8 3.9 2.0 2 0 0 2 2 2 0 Prominin GAS PF13851.6 RLN72650.1 - 7.5 5.8 36.7 4.1 6.7 21.7 2.9 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding EGF_2 PF07974.13 RLN72651.1 - 5.2e-19 68.3 116.2 3.4e-05 24.1 3.2 10.7 11 0 0 11 11 11 8 EGF-like domain Laminin_EGF PF00053.24 RLN72651.1 - 0.0011 19.1 88.2 0.1 12.8 9.5 8.0 7 1 1 8 8 8 5 Laminin EGF domain EGF PF00008.27 RLN72651.1 - 0.0016 18.7 80.1 0.0082 16.4 2.5 10.0 9 0 0 9 9 9 5 EGF-like domain hEGF PF12661.7 RLN72651.1 - 0.0085 16.7 4.3 0.0085 16.7 4.3 10.7 11 0 0 11 11 11 4 Human growth factor-like EGF IGPD PF00475.18 RLN72654.1 - 1.3e-59 200.7 1.1 2.4e-59 199.8 1.1 1.5 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase HAD_2 PF13419.6 RLN72654.1 - 1.9e-19 70.4 0.0 2.6e-18 66.8 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RLN72654.1 - 8.1e-11 42.6 0.0 1.1e-07 32.4 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RLN72654.1 - 1.7e-07 31.2 0.1 5.2e-07 29.6 0.1 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like SKN1 PF03935.15 RLN72655.1 - 7.7e-54 182.9 21.5 2.2e-35 122.1 10.7 4.9 2 2 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) zf-C2H2 PF00096.26 RLN72656.1 - 4.6e-17 61.4 13.8 2.4e-06 27.7 0.9 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN72656.1 - 5.4e-11 42.4 12.8 0.0015 19.2 0.6 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RLN72656.1 - 1e-09 38.4 19.4 3.6e-05 24.0 0.5 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_11 PF16622.5 RLN72656.1 - 1.4e-05 24.7 6.3 0.087 12.6 0.2 3.3 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 RLN72656.1 - 0.00079 19.7 2.2 0.079 13.3 0.8 2.8 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 RLN72656.1 - 0.036 14.1 10.9 0.058 13.4 0.5 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 RLN72656.1 - 0.046 14.4 3.0 1.1 9.9 0.0 3.2 2 1 2 4 4 3 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 RLN72656.1 - 0.054 13.8 0.3 6 7.3 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 RLN72656.1 - 0.066 13.4 2.6 3.1 7.9 0.4 2.5 1 1 1 2 2 2 0 Aberrant zinc-finger zf_ZIC PF18366.1 RLN72656.1 - 0.35 11.0 5.4 9 6.5 0.3 3.4 3 0 0 3 3 3 0 Zic proteins zinc finger domain GAGA PF09237.11 RLN72656.1 - 0.8 9.6 4.7 0.7 9.7 0.5 2.5 2 0 0 2 2 2 0 GAGA factor zf-C2H2 PF00096.26 RLN72657.1 - 7.5e-18 63.9 26.9 6.5e-06 26.3 1.7 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN72657.1 - 1.2e-14 53.7 25.1 0.0029 18.3 0.5 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RLN72657.1 - 1e-13 51.0 27.0 1.5e-05 25.2 1.8 5.3 5 0 0 5 5 5 3 Zinc-finger double domain FOXP-CC PF16159.5 RLN72657.1 - 8.4e-07 29.5 7.1 0.0026 18.3 0.0 4.3 2 1 3 5 5 5 2 FOXP coiled-coil domain zf-TRAF PF02176.18 RLN72657.1 - 8.3e-06 26.4 8.8 0.0082 16.8 1.8 2.4 1 1 1 2 2 2 2 TRAF-type zinc finger zf-C2H2_8 PF15909.5 RLN72657.1 - 0.0014 18.9 6.6 0.07 13.4 2.0 3.7 2 1 1 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 RLN72657.1 - 0.021 14.6 17.4 0.56 10.0 0.2 3.7 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 RLN72657.1 - 0.038 14.3 8.5 6.6 7.1 0.2 4.3 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 RLN72657.1 - 0.22 11.7 9.0 25 5.0 0.2 4.0 1 1 3 4 4 4 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 RLN72657.1 - 0.31 11.1 17.2 0.56 10.3 0.1 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-DNA_Pol PF08996.10 RLN72657.1 - 0.31 10.7 1.7 0.49 10.1 0.4 1.9 1 1 0 2 2 2 0 DNA Polymerase alpha zinc finger IBR PF01485.21 RLN72657.1 - 0.51 10.6 7.7 1.3 9.3 0.6 3.2 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain zf_ZIC PF18366.1 RLN72657.1 - 0.66 10.1 13.6 0.96 9.6 0.4 4.5 3 1 2 5 5 5 0 Zic proteins zinc finger domain Elicitin PF00964.17 RLN72658.1 - 1.2e-19 70.1 2.1 2.2e-19 69.3 2.1 1.4 1 0 0 1 1 1 1 Elicitin End_N_terminal PF12218.8 RLN72658.1 - 0.063 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase Sporozoite_P67 PF05642.11 RLN72658.1 - 0.79 7.7 6.4 0.53 8.3 5.0 1.2 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Spc7_N PF15402.6 RLN72658.1 - 4.6 5.4 8.2 5.7 5.1 8.2 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Elicitin PF00964.17 RLN72659.1 - 1.8e-21 76.0 4.1 3.6e-21 75.0 4.1 1.6 1 0 0 1 1 1 1 Elicitin Nramp PF01566.18 RLN72663.1 - 4.4e-103 345.0 11.6 4.4e-103 345.0 11.6 2.5 1 1 1 2 2 2 1 Natural resistance-associated macrophage protein SAE2 PF08573.10 RLN72665.1 - 1.3e-10 42.4 13.8 3.4e-06 28.1 0.4 3.7 3 2 1 4 4 4 2 DNA repair protein endonuclease SAE2/CtIP C-terminus Striatin PF08232.12 RLN72665.1 - 0.08 13.5 0.5 0.08 13.5 0.5 2.2 1 1 0 2 2 2 0 Striatin family PHD PF00628.29 RLN72667.1 - 5.5e-08 32.6 8.2 1.1e-07 31.6 8.2 1.6 1 0 0 1 1 1 1 PHD-finger RAMA PF18755.1 RLN72667.1 - 4.9e-06 26.9 0.0 1.8e-05 25.1 0.0 2.1 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated C1_1 PF00130.22 RLN72667.1 - 0.029 14.3 3.7 0.075 12.9 3.7 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 RLN72667.1 - 0.072 12.7 3.1 0.15 11.7 3.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1759 PF03564.15 RLN72667.1 - 0.26 11.2 2.3 0.37 10.7 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Prok-RING_1 PF14446.6 RLN72667.1 - 0.66 10.0 6.8 1.6 8.7 6.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 RLN72667.1 - 1.1 8.8 4.1 0.41 10.3 1.3 1.8 2 0 0 2 2 2 0 PHD-finger C1_2 PF03107.16 RLN72667.1 - 1.7 9.0 4.5 3.7 7.9 4.5 1.5 1 0 0 1 1 1 0 C1 domain WXG100 PF06013.12 RLN72668.1 - 0.35 11.1 15.0 2.4 8.5 0.2 4.2 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Hydrolase_4 PF12146.8 RLN72674.1 - 3.1e-49 167.4 0.0 3.9e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN72674.1 - 2.2e-16 61.2 0.5 3.1e-16 60.7 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 RLN72674.1 - 0.00015 21.6 0.2 0.044 13.6 0.1 2.7 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 RLN72674.1 - 0.00058 19.6 0.7 0.0019 17.9 0.7 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN72674.1 - 0.00073 19.1 0.1 0.005 16.3 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase PF07224.11 RLN72674.1 - 0.0018 17.3 0.0 0.0032 16.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 RLN72674.1 - 0.0025 16.8 0.0 0.0037 16.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Codanin-1_C PF15296.6 RLN72677.1 - 0.0072 16.4 0.1 0.017 15.2 0.1 1.5 1 0 0 1 1 1 1 Codanin-1 C-terminus RNA_pol_Rpc4 PF05132.14 RLN72677.1 - 0.75 10.2 11.3 2.3 8.6 2.4 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 Zip PF02535.22 RLN72677.1 - 2 7.5 12.6 1.1 8.4 2.0 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter DUF2201_N PF13203.6 RLN72677.1 - 2.2 7.8 8.9 0.84 9.2 4.1 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain Myc_N PF01056.18 RLN72677.1 - 2.4 8.0 15.8 1.4 8.7 7.0 2.1 2 0 0 2 2 2 0 Myc amino-terminal region DUF913 PF06025.12 RLN72677.1 - 4 6.3 9.5 8.5 5.2 3.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) TLP-20 PF06088.11 RLN72677.1 - 7.1 6.5 9.3 15 5.4 0.8 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Afi1 PF07792.12 RLN72677.1 - 9.8 6.7 14.9 2.3 8.7 3.7 2.7 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking KIAA1430 PF13879.6 RLN72678.1 - 7.9e-11 42.6 1.6 7.9e-11 42.6 1.6 1.9 1 1 1 2 2 2 2 KIAA1430 homologue MtN3_slv PF03083.16 RLN72682.1 - 7.9e-33 112.4 9.6 8.5e-21 73.8 4.1 2.5 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange DUF5079 PF16882.5 RLN72682.1 - 0.067 13.1 10.2 0.12 12.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5079) PQ-loop PF04193.14 RLN72682.1 - 0.1 12.4 5.3 6.8 6.5 0.0 3.7 4 0 0 4 4 4 0 PQ loop repeat Syndecan PF01034.20 RLN72682.1 - 0.71 9.8 0.0 0.71 9.8 0.0 2.9 4 0 0 4 4 4 0 Syndecan domain Nop14 PF04147.12 RLN72685.1 - 0.0089 14.3 9.4 0.011 14.0 9.4 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 RLN72685.1 - 0.081 11.2 5.7 0.1 10.9 5.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 RLN72685.1 - 0.11 12.3 4.7 0.16 11.8 4.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4611 PF15387.6 RLN72685.1 - 0.12 12.6 8.8 0.24 11.6 8.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) AIM3 PF17096.5 RLN72685.1 - 0.15 13.0 0.9 0.22 12.4 0.9 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 MPP6 PF10175.9 RLN72685.1 - 0.16 12.5 4.2 0.24 11.9 4.2 1.3 1 0 0 1 1 1 0 M-phase phosphoprotein 6 DNA_pol_phi PF04931.13 RLN72685.1 - 0.18 9.9 14.9 0.26 9.4 14.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 RLN72685.1 - 0.25 11.0 5.6 0.39 10.4 5.6 1.3 1 0 0 1 1 1 0 FAM176 family SDA1 PF05285.12 RLN72685.1 - 0.35 10.3 10.2 0.43 10.0 10.2 1.1 1 0 0 1 1 1 0 SDA1 TRAP_alpha PF03896.16 RLN72685.1 - 0.4 9.8 3.8 0.57 9.3 3.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BUD22 PF09073.10 RLN72685.1 - 0.5 9.7 8.1 0.59 9.4 8.1 1.1 1 0 0 1 1 1 0 BUD22 RXT2_N PF08595.11 RLN72685.1 - 0.56 10.2 8.1 1 9.3 8.1 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Radial_spoke PF04712.12 RLN72685.1 - 0.56 9.1 6.2 0.78 8.6 6.2 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Paf1 PF03985.13 RLN72685.1 - 0.71 8.8 8.4 0.92 8.4 8.4 1.1 1 0 0 1 1 1 0 Paf1 DUF4820 PF16091.5 RLN72685.1 - 0.83 9.0 4.7 1.1 8.5 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF2457 PF10446.9 RLN72685.1 - 0.84 8.7 18.4 1.1 8.4 18.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop53 PF07767.11 RLN72685.1 - 0.98 8.7 7.9 1.2 8.4 7.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CobT PF06213.12 RLN72685.1 - 1.5 8.2 10.2 1.9 7.8 10.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.13 RLN72685.1 - 2.1 8.2 10.5 2.9 7.7 10.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Cytomega_UL84 PF06284.11 RLN72685.1 - 2.2 6.6 4.3 2.6 6.4 4.3 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Sporozoite_P67 PF05642.11 RLN72685.1 - 8.7 4.3 9.3 7 4.6 8.0 1.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Astro_capsid_p PF12226.8 RLN72685.1 - 9.7 5.2 16.1 12 4.9 16.1 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Pkinase PF00069.25 RLN72686.1 - 3e-15 56.3 0.0 4e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN72686.1 - 6.1e-07 29.0 0.0 9.1e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN72686.1 - 0.018 14.4 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 RLN72686.1 - 0.036 13.0 0.0 0.052 12.5 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 RLN72686.1 - 0.098 12.2 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC_tran PF00005.27 RLN72689.1 - 9.8e-55 184.8 0.0 1.4e-27 96.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 RLN72689.1 - 1.8e-09 37.6 0.0 8.5e-09 35.4 0.0 1.8 1 1 1 2 2 2 1 ABC transporter transmembrane region AAA_22 PF13401.6 RLN72689.1 - 2.2e-06 28.0 0.5 0.12 12.7 0.0 3.9 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 RLN72689.1 - 5.6e-05 22.8 0.0 0.087 12.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN72689.1 - 0.00072 19.2 0.8 2.5 7.6 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 RLN72689.1 - 0.0045 17.5 0.1 6.6 7.3 0.1 3.3 2 1 1 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 RLN72689.1 - 0.0066 16.4 0.0 0.83 9.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_14 PF13173.6 RLN72689.1 - 0.0089 16.1 0.0 5.8 7.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 RLN72689.1 - 0.022 15.1 12.1 0.55 10.6 1.4 3.9 3 2 1 4 4 4 0 AAA ATPase domain IstB_IS21 PF01695.17 RLN72689.1 - 0.023 14.4 0.7 9.6 5.9 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_21 PF13304.6 RLN72689.1 - 0.031 14.1 0.2 16 5.2 0.0 3.2 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 RLN72689.1 - 0.033 13.9 0.9 1.4 8.6 0.0 3.0 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 RLN72689.1 - 0.058 13.5 0.0 3.8 7.6 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase APS_kinase PF01583.20 RLN72689.1 - 0.1 12.5 0.1 13 5.6 0.1 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_15 PF13175.6 RLN72689.1 - 0.18 11.5 0.0 0.35 10.5 0.0 1.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 RLN72689.1 - 0.66 10.1 5.2 5.3 7.2 0.0 4.0 3 1 0 3 3 3 0 AAA domain Helitron_like_N PF14214.6 RLN72697.1 - 3e-05 24.3 0.1 3e-05 24.3 0.1 2.3 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus MIP PF00230.20 RLN72701.1 - 2.7e-41 141.7 10.1 3.3e-41 141.5 10.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF872 PF05915.12 RLN72701.1 - 0.0043 17.2 0.1 0.014 15.6 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF872) MIP PF00230.20 RLN72702.1 - 2.1e-17 63.6 0.7 2.6e-17 63.3 0.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein RVT_1 PF00078.27 RLN72703.1 - 2.3e-12 46.9 0.0 5.7e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFIIS_M PF07500.14 RLN72703.1 - 0.11 13.0 1.6 0.33 11.5 0.4 2.2 1 1 2 3 3 3 0 Transcription factor S-II (TFIIS), central domain DUF2959 PF11172.8 RLN72703.1 - 0.26 11.4 3.9 0.3 11.2 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) TetR_C_6 PF13977.6 RLN72703.1 - 4.9 7.4 9.8 0.54 10.5 4.2 2.4 2 1 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal MIP PF00230.20 RLN72704.1 - 2.9e-43 148.2 13.2 3.8e-43 147.8 13.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 RLN72705.1 - 1.7e-38 132.6 1.1 2.3e-38 132.2 1.1 1.2 1 0 0 1 1 1 1 Major intrinsic protein WD40 PF00400.32 RLN72706.1 - 8.3e-47 156.2 25.4 1.8e-05 25.4 0.1 11.2 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN72706.1 - 4.4e-21 75.0 2.5 0.012 15.9 0.0 8.4 4 2 4 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 RLN72706.1 - 1.2e-14 54.5 3.2 2.2e-14 53.7 3.2 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 RLN72706.1 - 1.6e-05 24.1 5.7 2.2 7.2 0.0 6.5 4 1 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 RLN72706.1 - 0.00099 18.5 0.0 0.25 10.6 0.0 3.9 4 2 1 6 6 6 1 WD40-like domain Nup160 PF11715.8 RLN72706.1 - 0.01 14.5 4.2 1.1 7.8 0.0 3.3 3 1 0 3 3 3 0 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 RLN72706.1 - 0.031 13.5 0.0 16 4.6 0.0 3.5 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SDA1 PF05285.12 RLN72706.1 - 0.036 13.5 22.2 0.028 13.9 11.0 2.2 2 0 0 2 2 2 0 SDA1 DUF2956 PF11169.8 RLN72706.1 - 1.5 9.0 17.0 5 7.4 3.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) AIF_C PF14721.6 RLN72706.1 - 1.7 9.0 12.8 5.8 7.3 2.7 2.6 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CSRNP_N PF16019.5 RLN72706.1 - 4.7 7.1 7.8 4.5 7.1 2.6 2.3 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Hist_deacetyl PF00850.19 RLN72708.1 - 3.6e-15 56.3 0.0 5.7e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain DUF913 PF06025.12 RLN72708.1 - 0.11 11.5 0.2 0.13 11.2 0.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GMC_oxred_N PF00732.19 RLN72709.1 - 1.4e-94 316.8 0.0 1.7e-94 316.6 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 RLN72709.1 - 4.2e-07 29.4 0.1 0.025 13.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 RLN72709.1 - 2.6e-05 24.0 1.3 0.00015 21.5 1.3 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RLN72709.1 - 5.9e-05 22.4 0.0 0.0094 15.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RLN72709.1 - 7.5e-05 22.0 0.1 0.00013 21.2 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 RLN72709.1 - 0.0016 18.6 0.0 0.0045 17.2 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 RLN72709.1 - 0.019 15.5 0.1 1.2 9.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 RLN72709.1 - 0.039 13.2 0.0 0.1 11.8 0.0 1.6 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.7 RLN72709.1 - 0.055 12.8 0.6 1 8.6 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 RLN72709.1 - 0.15 10.7 0.2 0.69 8.6 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein ICL PF00463.21 RLN72710.1 - 1.4e-28 99.8 0.3 1.5e-28 99.6 0.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Ad_Cy_reg PF16701.5 RLN72710.1 - 0.013 15.2 0.0 0.015 15.0 0.0 1.0 1 0 0 1 1 1 0 Adenylate cyclase regulatory domain LAL_C2 PF18603.1 RLN72710.1 - 0.093 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 Pro_isomerase PF00160.21 RLN72711.1 - 2.4e-38 131.9 0.1 2.9e-38 131.6 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Palm_thioest PF02089.15 RLN72712.1 - 3.9e-42 144.8 5.5 3e-35 122.2 0.3 2.4 2 1 0 2 2 2 2 Palmitoyl protein thioesterase Spore_III_AF PF09581.10 RLN72714.1 - 0.075 13.1 1.7 0.11 12.6 1.7 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Pes-10 PF07149.11 RLN72714.1 - 0.099 11.7 2.3 0.16 11.0 2.3 1.2 1 0 0 1 1 1 0 Pes-10 CCDC71L PF15374.6 RLN72714.1 - 0.13 11.5 6.4 0.032 13.5 2.5 1.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 71L Metallophos PF00149.28 RLN72719.1 - 7.7e-16 59.2 2.6 1.1e-15 58.7 2.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Amidohydro_2 PF04909.14 RLN72720.1 - 6.6e-27 95.0 0.1 1.3e-26 94.1 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase Ribosomal_S19 PF00203.21 RLN72721.1 - 2.5e-32 110.6 0.1 3.6e-32 110.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 LRR_9 PF14580.6 RLN72722.1 - 4.3e-56 189.1 47.5 4.1e-12 46.0 0.8 7.9 5 3 3 8 8 8 7 Leucine-rich repeat LRR_4 PF12799.7 RLN72722.1 - 4.4e-53 176.3 91.1 5.7e-07 29.7 0.3 16.6 15 1 3 18 18 18 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN72722.1 - 1.4e-31 108.0 92.9 3.1e-05 23.6 5.6 14.0 9 4 5 15 15 15 13 Leucine rich repeat LRR_6 PF13516.6 RLN72722.1 - 0.016 15.2 67.2 1.2 9.4 0.0 17.5 20 0 0 20 20 20 0 Leucine Rich repeat RNase_P_p30 PF01876.16 RLN72723.1 - 7.3e-42 143.3 0.0 8.9e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 TP53IP5 PF15331.6 RLN72724.1 - 8.4 6.5 8.3 11 6.1 8.3 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Lin-8 PF03353.15 RLN72724.1 - 8.6 5.8 19.1 9.1 5.7 19.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist adh_short PF00106.25 RLN72725.1 - 9.2e-18 64.4 0.0 1.3e-12 47.6 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN72725.1 - 2.7e-13 50.0 0.5 2.2e-05 24.1 0.0 2.7 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase Spt4 PF06093.13 RLN72725.1 - 0.0086 16.2 1.2 0.034 14.2 0.3 2.4 2 0 0 2 2 2 1 Spt4/RpoE2 zinc finger Ig_4 PF16680.5 RLN72725.1 - 0.072 13.4 0.5 0.17 12.2 0.5 1.6 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain zf-ACC PF17848.1 RLN72725.1 - 0.12 12.5 0.2 0.25 11.4 0.2 1.5 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain bZIP_2 PF07716.15 RLN72729.1 - 0.00053 20.0 9.0 0.00053 20.0 9.0 2.4 2 0 0 2 2 2 1 Basic region leucine zipper BssS PF13991.6 RLN72729.1 - 0.00068 19.7 2.5 0.037 14.1 0.0 2.9 2 1 1 3 3 3 1 BssS protein family HBM PF16591.5 RLN72729.1 - 0.0063 16.0 8.0 0.012 15.1 8.0 1.3 1 0 0 1 1 1 1 Helical bimodular sensor domain SR-25 PF10500.9 RLN72729.1 - 0.21 11.2 6.8 0.07 12.7 3.8 1.6 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein FlgN PF05130.12 RLN72729.1 - 0.27 11.7 8.9 0.59 10.6 8.9 1.5 1 0 0 1 1 1 0 FlgN protein ABC_tran_CTD PF16326.5 RLN72729.1 - 0.4 11.0 7.6 0.063 13.5 2.8 2.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain bZIP_1 PF00170.21 RLN72729.1 - 0.42 10.7 9.3 0.36 11.0 7.4 1.8 1 1 0 1 1 1 0 bZIP transcription factor DUF4407 PF14362.6 RLN72729.1 - 7.5 5.8 9.9 11 5.3 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phe_ZIP PF08916.11 RLN72731.1 - 0.06 14.1 0.5 0.19 12.5 0.1 1.9 2 0 0 2 2 2 0 Phenylalanine zipper Adap_comp_sub PF00928.21 RLN72733.1 - 6.6e-21 74.9 0.0 9.3e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 RLN72733.1 - 0.0024 17.8 0.1 0.0045 16.9 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TniB PF05621.11 RLN72733.1 - 0.0093 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein Mon1 PF03164.14 RLN72733.1 - 0.15 11.1 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Trafficking protein Mon1 SDF PF00375.18 RLN72738.1 - 1.2e-65 222.0 20.5 1.4e-65 221.9 20.5 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Glyco_hydro_1 PF00232.18 RLN72740.1 - 2.4e-50 171.3 0.1 2.8e-50 171.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 GCN5L1 PF06320.13 RLN72741.1 - 0.0039 17.3 7.1 0.0039 17.3 7.1 3.6 1 1 1 3 3 3 1 GCN5-like protein 1 (GCN5L1) KASH_CCD PF14662.6 RLN72741.1 - 0.0069 16.2 18.4 0.0069 16.2 18.4 3.2 2 1 2 4 4 4 1 Coiled-coil region of CCDC155 or KASH bZIP_2 PF07716.15 RLN72741.1 - 0.018 15.1 7.3 0.018 15.1 7.3 6.7 7 2 1 8 8 8 0 Basic region leucine zipper Vac_Fusion PF02346.16 RLN72741.1 - 0.073 12.7 0.4 0.073 12.7 0.4 3.8 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 Atg14 PF10186.9 RLN72741.1 - 0.32 10.0 45.4 0.14 11.2 17.5 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Dot_icm_IcmQ PF09475.10 RLN72741.1 - 1 8.9 9.1 0.034 13.6 1.7 2.2 2 1 0 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) FlaC_arch PF05377.11 RLN72741.1 - 3.7 8.0 15.4 10 6.6 0.5 5.3 3 2 0 3 3 3 0 Flagella accessory protein C (FlaC) GIY-YIG PF01541.24 RLN72741.1 - 4 7.8 5.6 31 4.9 0.3 3.1 3 1 1 4 4 4 0 GIY-YIG catalytic domain GAS PF13851.6 RLN72741.1 - 7.7 5.8 55.4 2.2 7.6 1.8 5.0 1 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding Gp_dh_C PF02800.20 RLN72742.1 - 0.0078 15.8 0.1 0.022 14.4 0.0 1.7 2 1 1 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Hydrolase PF00702.26 RLN72743.1 - 7.4e-24 85.2 0.2 1e-23 84.7 0.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 RLN72743.1 - 4.2e-06 26.7 0.4 6.4e-05 22.8 0.5 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 RLN72743.1 - 0.0028 18.1 0.0 0.0058 17.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SAP PF02037.27 RLN72746.1 - 1.4e-07 31.1 0.3 1.4e-07 31.1 0.3 2.4 3 0 0 3 3 3 1 SAP domain RRM_1 PF00076.22 RLN72746.1 - 3.3e-05 23.6 0.1 8.6e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LEM PF03020.15 RLN72746.1 - 0.061 12.9 0.3 0.14 11.8 0.1 1.7 2 0 0 2 2 2 0 LEM domain RAP1 PF07218.11 RLN72746.1 - 3.3 5.9 11.7 3.6 5.8 11.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Spem1 PF15670.5 RLN72746.1 - 9.3 5.7 11.6 13 5.3 11.6 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 SOBP PF15279.6 RLN72746.1 - 9.8 6.7 14.1 12 6.4 14.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein FA_hydroxylase PF04116.13 RLN72747.1 - 5.1e-22 78.7 26.7 5.1e-22 78.7 26.7 2.1 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily SNF2_N PF00176.23 RLN72748.1 - 3.3e-61 207.0 0.0 4.9e-61 206.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN72748.1 - 1.5e-07 31.8 0.0 3.1e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 RLN72748.1 - 1.5e-05 24.7 8.3 3.8e-05 23.5 8.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN72748.1 - 0.00053 19.8 8.0 0.0015 18.3 8.0 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN72748.1 - 0.0069 16.3 9.1 0.018 15.0 9.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain F-box-like PF12937.7 RLN72748.1 - 0.037 13.9 0.0 0.09 12.7 0.0 1.7 1 0 0 1 1 1 0 F-box-like ResIII PF04851.15 RLN72748.1 - 0.12 12.3 0.0 7.7 6.5 0.1 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 RLN72748.1 - 0.34 10.8 10.0 0.93 9.4 10.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN72748.1 - 0.49 10.3 11.4 1.3 8.9 11.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RLN72748.1 - 2 8.6 9.5 5.1 7.3 9.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 RLN72748.1 - 2.2 8.4 10.2 5 7.2 10.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger INCENP_ARK-bind PF03941.15 RLN72748.1 - 7.3 6.6 7.1 33 4.5 0.0 3.3 3 1 0 3 3 3 0 Inner centromere protein, ARK binding region UDPGP PF01704.18 RLN72749.1 - 9.5e-97 324.2 0.0 2.3e-49 168.2 0.0 2.1 2 0 0 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 RLN72749.1 - 5.6e-06 26.8 0.1 0.077 13.3 0.0 3.0 3 0 0 3 3 3 2 MobA-like NTP transferase domain RRM_4 PF10598.9 RLN72749.1 - 0.063 13.6 0.0 7 7.1 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif of the spliceosomal PrP8 OHCU_decarbox PF09349.10 RLN72750.1 - 3.2e-32 112.2 0.1 3.8e-32 111.9 0.1 1.0 1 0 0 1 1 1 1 OHCU decarboxylase N6_Mtase PF02384.16 RLN72754.1 - 0.00021 20.7 0.0 0.00028 20.3 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_23 PF13489.6 RLN72754.1 - 0.0027 17.6 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN72754.1 - 0.0057 17.3 0.0 0.017 15.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN72754.1 - 0.006 16.1 0.0 0.0099 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 RLN72754.1 - 0.014 16.0 0.0 0.029 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 RLN72754.1 - 0.045 12.8 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Oscp1 PF10188.9 RLN72755.1 - 6.9e-64 215.2 4.8 9.4e-64 214.7 4.8 1.2 1 0 0 1 1 1 1 Organic solute transport protein 1 FYVE PF01363.21 RLN72756.1 - 1.5e-15 57.1 7.7 1.5e-15 57.1 7.7 3.5 3 2 0 3 3 3 1 FYVE zinc finger WW PF00397.26 RLN72756.1 - 1.4e-12 47.5 0.2 6.5e-12 45.3 0.1 2.1 2 0 0 2 2 2 1 WW domain Arm PF00514.23 RLN72756.1 - 6.4e-05 22.9 7.4 0.98 9.6 0.2 6.9 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat zf-LSD1 PF06943.12 RLN72756.1 - 0.00028 20.7 3.7 0.00028 20.7 3.7 3.6 3 0 0 3 3 3 1 LSD1 zinc finger Inhibitor_I36 PF03995.13 RLN72757.1 - 0.00062 19.6 1.8 0.0023 17.8 1.7 2.0 1 1 1 2 2 2 1 Peptidase inhibitor family I36 Asn_synthase PF00733.21 RLN72758.1 - 7.6e-19 68.6 0.0 9.1e-15 55.2 0.0 2.4 1 1 1 2 2 2 2 Asparagine synthase MMACHC PF16690.5 RLN72758.1 - 0.00027 20.6 0.1 0.15 11.7 0.0 3.4 3 1 1 4 4 4 2 Methylmalonic aciduria and homocystinuria type C family DZR PF12773.7 RLN72758.1 - 0.053 13.6 1.9 0.13 12.3 1.9 1.6 1 0 0 1 1 1 0 Double zinc ribbon Aldo_ket_red PF00248.21 RLN72759.1 - 1.8e-67 227.6 0.0 2e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TGase_elicitor PF16683.5 RLN72760.1 - 7.7e-67 225.6 0.2 8.4e-67 225.5 0.2 1.0 1 0 0 1 1 1 1 Transglutaminase elicitor PALP PF00291.25 RLN72761.1 - 1.2e-42 146.4 0.1 1.3e-42 146.2 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme E1-E2_ATPase PF00122.20 RLN72762.1 - 2e-31 108.9 1.9 2.5e-31 108.6 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 RLN72762.1 - 2.3e-07 31.3 0.1 0.0001 22.7 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN72762.1 - 0.00075 19.5 0.1 0.0021 18.1 0.1 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 RLN72762.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus 2-Hacid_dh_C PF02826.19 RLN72763.1 - 3.2e-44 150.4 0.0 4.5e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 RLN72763.1 - 2.8e-07 30.9 0.0 4.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 RLN72763.1 - 0.0023 18.0 0.0 0.0047 17.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Rossmann-like PF10727.9 RLN72763.1 - 0.0044 16.9 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Rossmann-like domain IlvN PF07991.12 RLN72763.1 - 0.0053 16.4 0.0 0.0085 15.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 RLN72763.1 - 0.0075 16.8 0.0 0.019 15.5 0.0 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 RLN72763.1 - 0.095 12.7 0.2 1.2 9.1 0.2 2.2 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 RLN72763.1 - 0.17 11.7 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 RLN72763.1 - 0.18 11.1 0.1 0.39 10.0 0.0 1.5 2 0 0 2 2 2 0 ThiF family CN_hydrolase PF00795.22 RLN72764.1 - 1e-46 159.5 0.0 1.3e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF2808 PF10989.8 RLN72768.1 - 0.0083 16.1 0.1 18 5.3 0.0 5.2 6 0 0 6 6 6 1 Protein of unknown function (DUF2808) Glyco_transf_20 PF00982.21 RLN72770.1 - 3.5e-103 345.8 0.0 4.4e-103 345.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 RLN72770.1 - 7.1e-47 159.5 0.0 1.1e-46 158.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 RLN72770.1 - 0.23 11.2 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase NDK PF00334.19 RLN72771.1 - 1.4e-06 28.4 0.0 0.00057 19.9 0.0 2.4 1 1 1 2 2 2 2 Nucleoside diphosphate kinase ATP_bind_1 PF03029.17 RLN72772.1 - 3.1e-80 269.4 0.1 4.3e-80 269.0 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.23 RLN72772.1 - 0.00022 21.3 0.0 0.00038 20.5 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 RLN72772.1 - 0.00023 20.3 0.0 0.00048 19.2 0.0 1.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 RLN72772.1 - 0.00043 20.1 0.0 0.00077 19.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RLN72772.1 - 0.00059 20.3 0.5 0.01 16.2 0.5 2.2 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 RLN72772.1 - 0.0017 17.7 0.0 0.027 13.8 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin SRP54 PF00448.22 RLN72772.1 - 0.003 17.2 0.0 0.0059 16.3 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain KTI12 PF08433.10 RLN72772.1 - 0.0035 16.8 0.0 0.013 14.9 0.0 1.9 2 0 0 2 2 2 1 Chromatin associated protein KTI12 MMR_HSR1 PF01926.23 RLN72772.1 - 0.0052 16.9 0.0 0.051 13.7 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 RLN72772.1 - 0.006 16.9 0.0 0.017 15.4 0.0 1.9 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 RLN72772.1 - 0.0075 15.9 0.0 0.12 12.0 0.0 2.6 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 RLN72772.1 - 0.024 15.2 0.1 0.13 12.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 RLN72772.1 - 0.028 14.6 0.0 0.12 12.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 RLN72772.1 - 0.043 14.2 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 RLN72772.1 - 0.059 13.3 0.0 0.51 10.2 0.0 2.2 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RLN72772.1 - 0.065 12.9 0.0 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 RLN72772.1 - 0.12 11.5 0.0 0.65 9.0 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 RLN72772.1 - 0.14 12.0 0.1 17 5.3 0.0 3.0 2 1 1 3 3 3 0 RsgA GTPase Asp PF00026.23 RLN72773.1 - 8.2e-19 68.2 0.0 8.6e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 RLN72773.1 - 0.0056 16.5 0.0 0.0067 16.2 0.0 1.1 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal LRR_4 PF12799.7 RLN72775.1 - 4.1e-12 46.1 3.4 6.1e-05 23.3 0.0 3.9 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN72775.1 - 3.5e-10 39.5 7.7 0.00087 19.0 0.6 4.0 2 1 1 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 RLN72775.1 - 2.9e-07 30.1 0.6 9.5e-07 28.5 0.5 1.8 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 RLN72775.1 - 2.8e-05 24.1 4.1 37 5.4 0.1 6.7 7 0 0 7 7 7 0 Leucine Rich Repeat Nudix_hydro PF18290.1 RLN72775.1 - 0.091 12.8 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 Nudix hydrolase domain LRR_6 PF13516.6 RLN72775.1 - 0.46 10.7 14.1 12 6.2 0.0 5.8 7 0 0 7 7 7 0 Leucine Rich repeat Phosphodiest PF01663.22 RLN72776.1 - 1.4e-10 41.4 0.1 2.2e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RLN72776.1 - 0.0014 18.1 0.1 0.0089 15.5 0.0 2.0 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 RLN72776.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily UCH PF00443.29 RLN72777.1 - 1.1e-42 146.4 0.0 2.7e-42 145.0 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN72777.1 - 6.6e-14 52.2 0.0 5.3e-10 39.4 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 RLN72777.1 - 0.0018 17.9 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family HECT PF00632.25 RLN72778.1 - 1.2e-55 189.2 0.0 2e-55 188.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 RLN72778.1 - 1.2e-53 180.3 2.3 6.9e-23 81.0 0.1 3.6 3 0 0 3 3 3 3 SPRY domain MIB_HERC2 PF06701.13 RLN72778.1 - 3.3e-18 65.7 6.9 9.6e-18 64.2 6.9 1.9 1 0 0 1 1 1 1 Mib_herc2 UBA PF00627.31 RLN72778.1 - 9.8e-15 54.1 1.6 4e-07 29.8 0.3 2.9 2 0 0 2 2 2 2 UBA/TS-N domain Neuralized PF07177.12 RLN72778.1 - 0.18 11.8 0.0 1.4 8.9 0.0 2.6 3 0 0 3 3 3 0 Neuralized DUF2723 PF11028.8 RLN72780.1 - 2e-17 63.7 3.2 3.4e-17 62.9 3.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2723) Aldo_ket_red PF00248.21 RLN72782.1 - 1.2e-69 234.7 0.0 1.4e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PDR_CDR PF06422.12 RLN72787.1 - 1.9e-10 40.5 0.0 2.9e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 CDR ABC transporter ABC2_membrane PF01061.24 RLN72787.1 - 2.4e-05 23.8 3.2 2.4e-05 23.8 3.2 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 RLN72787.1 - 0.024 13.7 1.2 0.03 13.4 1.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3533 PF12051.8 RLN72787.1 - 0.027 13.4 1.3 1.9 7.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) PDR_assoc PF08370.11 RLN72787.1 - 0.029 14.1 0.1 0.061 13.1 0.1 1.6 1 0 0 1 1 1 0 Plant PDR ABC transporter associated UCH PF00443.29 RLN72790.1 - 2.4e-15 56.8 0.0 3.3e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN72790.1 - 1.8e-10 41.0 0.0 5.7e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PDZ PF00595.24 RLN72790.1 - 0.00015 22.0 0.0 0.00031 21.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RLN72790.1 - 0.00052 19.8 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain zf-RanBP PF00641.18 RLN72790.1 - 0.0072 15.6 1.7 0.0072 15.6 1.7 2.6 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others PDZ_2 PF13180.6 RLN72790.1 - 0.096 13.0 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Zn-ribbon_8 PF09723.10 RLN72790.1 - 1.4 9.1 6.4 41 4.4 0.0 4.1 4 0 0 4 4 4 0 Zinc ribbon domain Ank_2 PF12796.7 RLN72791.1 - 2.1e-51 172.4 18.9 5.8e-09 36.4 0.0 10.3 6 4 8 14 14 14 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN72791.1 - 4.9e-45 151.3 30.1 3.9e-08 33.7 0.1 15.7 8 4 8 16 16 16 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN72791.1 - 1e-40 137.2 38.7 0.00025 21.3 0.3 23.0 10 7 16 26 26 26 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN72791.1 - 8.4e-30 99.5 10.9 1.4 9.7 0.0 20.6 19 3 3 22 22 22 3 Ankyrin repeat Ank PF00023.30 RLN72791.1 - 1.1e-07 32.0 3.8 81 3.9 0.0 12.0 7 3 3 10 10 8 0 Ankyrin repeat DUF5049 PF16468.5 RLN72791.1 - 4.8e-07 29.6 0.6 55 3.8 0.0 9.6 5 4 7 12 12 12 0 Domain of unknown function (DUF5049) DUF5020 PF16412.5 RLN72791.1 - 0.0017 18.3 0.1 2.6 7.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF5020) GST_N_3 PF13417.6 RLN72791.1 - 0.0071 16.7 0.0 10 6.6 0.0 3.6 4 0 0 4 4 4 1 Glutathione S-transferase, N-terminal domain LURAP PF14854.6 RLN72791.1 - 0.046 13.7 0.4 26 4.8 0.0 4.8 3 1 1 4 4 4 0 Leucine rich adaptor protein HSP20 PF00011.21 RLN72791.1 - 0.12 12.5 0.0 1.1e+02 3.0 0.0 3.9 4 0 0 4 4 4 0 Hsp20/alpha crystallin family DUF2462 PF09495.10 RLN72791.1 - 0.39 11.5 1.2 1.3e+02 3.4 0.0 4.6 6 0 0 6 6 6 0 Protein of unknown function (DUF2462) DUF1987 PF09345.10 RLN72791.1 - 0.95 9.1 18.4 5.3 6.7 0.0 7.5 11 0 0 11 11 11 0 Domain of unknown function (DUF1987) Bin3 PF06859.12 RLN72791.1 - 6.3 7.5 7.5 28 5.4 0.0 4.9 6 0 0 6 6 4 0 Bicoid-interacting protein 3 (Bin3) SIT PF15330.6 RLN72792.1 - 0.022 15.2 1.0 0.032 14.7 1.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT EloA-BP1 PF15870.5 RLN72792.1 - 0.039 14.2 0.2 0.33 11.2 0.4 2.0 2 0 0 2 2 2 0 ElonginA binding-protein 1 TRP PF06011.12 RLN72793.1 - 0.069 11.9 6.5 0.085 11.6 6.5 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel zf-RanBP PF00641.18 RLN72794.1 - 5.3e-05 22.4 0.8 9.6e-05 21.6 0.8 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DZR PF12773.7 RLN72794.1 - 0.04 14.0 0.6 0.068 13.2 0.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon Enolase_C PF00113.22 RLN72800.1 - 3.1e-148 492.8 0.0 3.9e-148 492.5 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 RLN72800.1 - 2.7e-57 192.6 0.0 4.5e-57 191.8 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 RLN72800.1 - 1.1e-09 38.2 0.0 1.8e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 RLN72800.1 - 1.4e-06 27.7 0.4 3.2e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus EccE PF11203.8 RLN72800.1 - 0.026 14.9 0.1 2.1 8.8 0.0 2.5 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE ParB PF08775.10 RLN72801.1 - 0.29 11.6 2.2 0.53 10.8 0.2 2.2 2 0 0 2 2 2 0 ParB family CHB_HEX PF03173.13 RLN72804.1 - 0.12 12.1 0.1 0.3 10.8 0.1 1.7 1 1 0 1 1 1 0 Putative carbohydrate binding domain ABC_tran PF00005.27 RLN72805.1 - 1.2e-06 29.1 0.1 2.4e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 RLN72805.1 - 0.00083 19.8 0.2 0.0013 19.1 0.2 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 RLN72805.1 - 0.001 19.0 0.1 0.0012 18.7 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN72805.1 - 0.0025 17.5 0.4 0.0051 16.5 0.1 1.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 RLN72805.1 - 0.0029 16.9 0.1 0.0058 15.9 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 RLN72805.1 - 0.0089 16.3 0.1 0.019 15.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 RLN72805.1 - 0.0093 15.1 0.1 0.011 14.8 0.1 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 RLN72805.1 - 0.027 14.5 0.5 0.065 13.3 0.1 1.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_25 PF13481.6 RLN72805.1 - 0.033 13.8 0.3 0.061 12.9 0.2 1.6 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 RLN72805.1 - 0.038 13.2 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 RLN72805.1 - 0.042 13.9 0.1 0.088 12.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 RLN72805.1 - 0.044 13.5 0.2 0.29 10.8 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 RLN72805.1 - 0.16 12.5 0.0 0.31 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 RLN72807.1 - 4.5e-56 190.1 0.0 6.2e-56 189.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN72807.1 - 6.7e-31 107.5 0.0 9.8e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN72807.1 - 0.00067 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN72807.1 - 0.00079 19.4 0.1 0.0033 17.4 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN72807.1 - 0.0027 17.1 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RLN72807.1 - 0.022 13.7 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FYVE PF01363.21 RLN72807.1 - 0.074 13.2 16.6 0.072 13.2 13.4 2.3 2 0 0 2 2 2 0 FYVE zinc finger FYVE_2 PF02318.16 RLN72807.1 - 1 9.6 10.0 3.1 8.0 10.0 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger cNMP_binding PF00027.29 RLN72810.1 - 2.4e-19 69.2 0.0 5.1e-09 36.1 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 RLN72810.1 - 1e-14 54.2 14.6 3.8e-09 36.4 3.2 4.1 3 0 0 3 3 3 3 Ion channel Ion_trans PF00520.31 RLN72810.1 - 2.2e-14 53.3 19.6 9.5e-07 28.3 3.0 3.2 2 1 0 2 2 2 2 Ion transport protein HSP70 PF00012.20 RLN72812.1 - 1.4e-71 241.5 0.0 3.9e-71 240.0 0.0 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN72812.1 - 7.3e-12 44.7 0.0 8.5e-10 38.0 0.0 2.1 1 1 0 1 1 1 1 MreB/Mbl protein NLE PF08154.12 RLN72812.1 - 0.06 13.9 0.1 2.5 8.7 0.0 3.0 3 0 0 3 3 3 0 NLE (NUC135) domain StbA PF06406.11 RLN72812.1 - 0.18 11.0 0.0 0.41 9.8 0.0 1.5 2 0 0 2 2 2 0 StbA protein zf-Nse PF11789.8 RLN72817.1 - 5.6e-05 22.9 1.0 0.00017 21.4 1.0 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.12 RLN72817.1 - 0.023 14.0 0.3 0.04 13.3 0.3 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_UBOX PF13445.6 RLN72817.1 - 0.031 14.3 3.1 0.075 13.1 3.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 RLN72817.1 - 0.039 14.3 3.0 0.11 12.9 3.0 1.8 1 0 0 1 1 1 0 Ring finger domain Syntaxin-6_N PF09177.11 RLN72817.1 - 0.11 13.0 1.4 0.29 11.7 1.4 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal CCDC-167 PF15188.6 RLN72817.1 - 0.24 11.7 1.8 0.63 10.4 1.8 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 zf-C3HC4_2 PF13923.6 RLN72817.1 - 0.4 10.5 3.7 0.87 9.5 3.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN72817.1 - 0.43 10.6 2.4 1.2 9.1 2.4 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-Nse PF11789.8 RLN72818.1 - 0.0018 18.1 0.4 0.0033 17.2 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 RLN72818.1 - 0.13 12.3 3.2 0.27 11.3 3.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 RLN72818.1 - 0.27 11.6 3.2 0.63 10.4 3.2 1.7 1 0 0 1 1 1 0 Ring finger domain DivIC PF04977.15 RLN72818.1 - 0.98 9.2 4.0 2.1 8.2 4.0 1.6 1 0 0 1 1 1 0 Septum formation initiator AP1AR PF15745.5 RLN72818.1 - 1.9 8.0 5.3 2.9 7.5 5.3 1.2 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein Cellulase PF00150.18 RLN72819.1 - 7e-32 111.0 0.0 9.2e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) zf-Nse PF11789.8 RLN72820.1 - 5.7e-05 22.8 1.0 0.00017 21.4 1.0 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.12 RLN72820.1 - 0.023 14.1 0.3 0.04 13.3 0.3 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_UBOX PF13445.6 RLN72820.1 - 0.033 14.2 3.1 0.075 13.1 3.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 RLN72820.1 - 0.046 14.0 3.0 0.11 12.9 3.0 1.7 1 0 0 1 1 1 0 Ring finger domain Spore_YtrH PF14034.6 RLN72820.1 - 0.068 13.3 0.2 28 4.9 0.0 3.3 3 0 0 3 3 3 0 Sporulation protein YtrH Syntaxin-6_N PF09177.11 RLN72820.1 - 0.13 12.9 1.6 0.34 11.5 1.6 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal CCDC-167 PF15188.6 RLN72820.1 - 0.25 11.7 1.8 0.63 10.4 1.8 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 zf-C3HC4_2 PF13923.6 RLN72820.1 - 0.41 10.5 3.7 0.87 9.5 3.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN72820.1 - 0.42 10.6 2.4 1.2 9.1 2.4 1.9 1 1 0 1 1 1 0 zinc-RING finger domain zf-Nse PF11789.8 RLN72821.1 - 0.00095 18.9 0.3 0.0018 18.0 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit TerY_C PF15616.6 RLN72821.1 - 0.008 16.3 0.2 0.015 15.4 0.2 1.4 1 0 0 1 1 1 1 TerY-C metal binding domain zf-RING_UBOX PF13445.6 RLN72821.1 - 0.025 14.6 1.9 0.049 13.7 1.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_10 PF16685.5 RLN72821.1 - 0.11 12.7 1.9 0.21 11.7 1.9 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_2 PF13639.6 RLN72821.1 - 0.28 11.5 2.8 0.53 10.7 2.8 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 RLN72821.1 - 0.55 10.1 3.1 0.97 9.3 3.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) OmpH PF03938.14 RLN72821.1 - 3.3 8.0 10.3 7 7.0 10.3 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Tmemb_9 PF05434.11 RLN72821.1 - 7.7 6.4 6.5 4.1 7.3 3.6 1.9 2 0 0 2 2 2 0 TMEM9 RSN1_7TM PF02714.15 RLN72822.1 - 1.1e-37 129.9 24.2 2.2e-37 128.9 24.2 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 RLN72822.1 - 7.9e-34 116.7 0.1 3.7e-33 114.5 0.1 2.3 1 1 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 RLN72822.1 - 8.9e-25 87.9 0.1 8.5e-16 58.7 0.0 2.3 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter Cyt-b5 PF00173.28 RLN72831.1 - 9.1e-13 48.2 0.0 1.8e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ARPC4 PF05856.12 RLN72832.1 - 9.1e-25 87.2 0.8 1e-24 87.1 0.8 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) EF_TS PF00889.19 RLN72834.1 - 1.3e-54 185.0 0.7 2e-54 184.4 0.7 1.3 1 0 0 1 1 1 1 Elongation factor TS ARPC4 PF05856.12 RLN72836.1 - 3.8e-44 150.3 3.2 4.9e-44 149.9 3.2 1.1 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Spermine_synth PF01564.17 RLN72837.1 - 7e-41 139.7 0.0 1.2e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 RLN72837.1 - 7.3e-10 38.6 0.1 1.4e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 RLN72837.1 - 0.0013 19.4 0.0 0.0044 17.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_30 PF05430.11 RLN72837.1 - 0.031 14.1 0.0 0.069 13.0 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.12 RLN72837.1 - 0.071 13.8 0.0 0.63 10.7 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain DUF2804 PF10974.8 RLN72838.1 - 4.8e-38 131.5 0.0 9.2e-38 130.6 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2804) FYVE PF01363.21 RLN72839.1 - 3.2e-06 27.2 18.5 7.5e-06 26.0 16.3 2.2 2 0 0 2 2 2 1 FYVE zinc finger zf-C2H2_4 PF13894.6 RLN72839.1 - 3.3 8.8 6.9 12 7.1 0.3 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger WW PF00397.26 RLN72840.1 - 0.0022 18.1 0.8 0.004 17.2 0.8 1.5 1 0 0 1 1 1 1 WW domain FYVE PF01363.21 RLN72841.1 - 3e-06 27.3 6.2 3e-06 27.3 6.2 1.9 2 0 0 2 2 2 1 FYVE zinc finger Peptidase_M15_2 PF05951.13 RLN72841.1 - 0.18 11.5 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) FYVE_2 PF02318.16 RLN72841.1 - 0.32 11.2 4.0 0.72 10.1 4.0 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_UBOX PF13445.6 RLN72841.1 - 0.66 10.0 6.0 0.3 11.1 2.7 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 RLN72841.1 - 1.1 9.7 6.7 3.9 7.9 6.7 2.1 1 0 0 1 1 1 0 Ring finger domain ABC_membrane PF00664.23 RLN72843.1 - 7.5e-78 261.9 31.2 5.5e-39 134.5 10.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN72843.1 - 4e-55 186.1 0.4 2.9e-31 108.8 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN72843.1 - 4.2e-10 39.4 11.7 0.0069 15.9 0.1 4.3 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RLN72843.1 - 3.1e-06 26.8 1.0 0.052 13.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN72843.1 - 9.9e-06 25.6 0.1 0.13 12.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RLN72843.1 - 1.9e-05 24.7 3.2 0.016 15.3 0.1 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 RLN72843.1 - 6.4e-05 22.9 1.8 0.96 9.2 0.1 3.9 2 2 2 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RLN72843.1 - 0.00071 20.1 0.4 1.8 9.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 RLN72843.1 - 0.011 15.5 0.2 0.79 9.4 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein Roc PF08477.13 RLN72843.1 - 0.012 15.8 0.4 0.88 9.8 0.1 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 RLN72843.1 - 0.024 15.1 1.3 2.6 8.4 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 RLN72843.1 - 0.027 13.7 0.8 6.5 6.0 0.1 2.8 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 RLN72843.1 - 0.033 13.8 1.5 1.1 8.8 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 RLN72843.1 - 0.068 13.4 3.2 10 6.4 0.2 3.0 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 RLN72843.1 - 0.11 12.0 0.1 4 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RLN72843.1 - 0.12 12.3 1.2 2.4 8.0 0.0 2.9 3 0 0 3 3 3 0 NACHT domain NB-ARC PF00931.22 RLN72843.1 - 0.12 11.5 2.2 4.9 6.3 0.0 2.9 2 1 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 RLN72843.1 - 0.16 11.5 0.4 4.6 6.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 RLN72843.1 - 0.16 11.6 2.5 7.4 6.2 0.1 2.9 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 RLN72843.1 - 0.18 11.8 7.2 3.5 7.6 0.2 3.1 3 0 0 3 3 3 0 Dynamin family AAA_15 PF13175.6 RLN72843.1 - 0.23 11.1 0.2 5 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.15 RLN72843.1 - 0.46 10.4 3.1 16 5.4 0.6 3.3 2 1 0 2 2 2 0 NTPase DUF87 PF01935.17 RLN72843.1 - 3.5 7.7 9.6 0.81 9.7 0.3 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 RLN72843.1 - 8 6.2 6.4 28 4.4 0.2 3.5 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein p450 PF00067.22 RLN72844.1 - 4.8e-69 233.3 0.0 6.1e-69 232.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.7 RLN72846.1 - 2.8e-05 24.6 0.0 0.0064 17.1 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN72846.1 - 0.001 19.3 1.2 10 6.5 0.1 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) ABC_membrane PF00664.23 RLN72850.1 - 1.1e-48 166.3 1.3 1.7e-48 165.7 1.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN72850.1 - 1.1e-12 48.6 0.0 1.9e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 RLN72850.1 - 0.0018 18.2 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN72850.1 - 0.019 14.7 0.2 0.042 13.6 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.20 RLN72850.1 - 0.19 11.6 0.1 3.1 7.7 0.0 2.6 3 0 0 3 3 3 0 Adenylylsulphate kinase DUF4743 PF15916.5 RLN72851.1 - 3.4e-14 52.9 0.0 6.6e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 RLN72851.1 - 4.3e-07 30.0 0.0 8e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Herpes_UL32 PF06070.11 RLN72852.1 - 0.0036 15.1 1.0 0.006 14.4 1.0 1.3 1 0 0 1 1 1 1 Herpesvirus large structural phosphoprotein UL32 Mito_carr PF00153.27 RLN72853.1 - 3.9e-50 167.8 2.2 1.2e-18 66.8 0.1 4.0 2 1 1 3 3 3 3 Mitochondrial carrier protein AAA_25 PF13481.6 RLN72854.1 - 1.3e-22 80.3 0.0 2.9e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Toprim_2 PF13155.6 RLN72854.1 - 1.9e-11 44.3 0.0 5.6e-11 42.7 0.0 1.9 2 0 0 2 2 1 1 Toprim-like AAA_22 PF13401.6 RLN72854.1 - 4.5e-08 33.5 0.0 1.2e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 RLN72854.1 - 2.3e-07 30.4 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Toprim_3 PF13362.6 RLN72854.1 - 3.9e-07 30.3 0.0 2e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 Toprim domain AAA_16 PF13191.6 RLN72854.1 - 2.8e-06 27.8 0.0 6.4e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Toprim_4 PF13662.6 RLN72854.1 - 9.9e-06 25.9 0.0 5.8e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Toprim domain ATPase PF06745.13 RLN72854.1 - 5.4e-05 22.6 0.0 9.9e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 KaiC ABC_tran PF00005.27 RLN72854.1 - 0.0014 19.2 0.1 0.0029 18.1 0.1 1.5 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 RLN72854.1 - 0.0036 17.8 0.1 0.0095 16.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain zf-CHC2 PF01807.20 RLN72854.1 - 0.0073 16.1 0.5 0.015 15.1 0.5 1.5 1 0 0 1 1 1 1 CHC2 zinc finger AAA_29 PF13555.6 RLN72854.1 - 0.0077 16.0 0.2 0.026 14.3 0.2 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 RLN72854.1 - 0.0078 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein PRK PF00485.18 RLN72854.1 - 0.011 15.5 0.0 0.045 13.5 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RsgA_GTPase PF03193.16 RLN72854.1 - 0.016 15.2 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 RLN72854.1 - 0.016 15.5 0.8 0.042 14.1 0.5 2.0 1 1 1 2 2 2 0 AAA domain ATPase_2 PF01637.18 RLN72854.1 - 0.019 14.9 0.1 0.098 12.6 0.0 2.1 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea Toprim PF01751.22 RLN72854.1 - 0.02 15.1 0.0 0.074 13.3 0.0 2.0 1 1 0 1 1 1 0 Toprim domain Rad17 PF03215.15 RLN72854.1 - 0.02 14.8 0.1 0.052 13.5 0.1 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain cobW PF02492.19 RLN72854.1 - 0.022 14.3 0.7 0.046 13.3 0.3 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 RLN72854.1 - 0.028 14.3 0.2 0.056 13.4 0.2 1.5 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 RLN72854.1 - 0.029 14.4 0.1 0.069 13.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 RLN72854.1 - 0.037 13.1 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 RLN72854.1 - 0.043 14.2 0.1 0.097 13.1 0.1 1.6 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 RLN72854.1 - 0.05 13.6 0.2 0.27 11.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 RLN72854.1 - 0.089 12.7 0.2 0.19 11.6 0.2 1.6 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 RLN72854.1 - 0.11 11.7 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain Lar_restr_allev PF14354.6 RLN72854.1 - 0.11 12.9 0.4 0.28 11.6 0.4 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar AAA_21 PF13304.6 RLN72854.1 - 0.12 12.1 0.1 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 RLN72854.1 - 0.12 12.9 0.1 0.48 11.0 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 RLN72854.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.9 RLN72854.1 - 0.15 11.2 0.5 0.25 10.4 0.1 1.5 2 0 0 2 2 1 0 Mitochondrial ribosomal death-associated protein 3 Zn_Tnp_IS1595 PF12760.7 RLN72854.1 - 0.31 11.1 1.5 0.85 9.6 1.5 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-CCHC_2 PF13696.6 RLN72854.1 - 1.3 9.0 4.7 1 9.3 1.6 2.2 2 0 0 2 2 2 0 Zinc knuckle DEAD PF00270.29 RLN72855.1 - 3.1e-36 124.8 0.1 1.6e-35 122.5 0.1 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN72855.1 - 9.1e-26 90.4 0.1 5.2e-25 88.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN72855.1 - 8e-05 22.7 0.0 0.00024 21.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDC45 PF02724.14 RLN72855.1 - 0.064 11.5 19.4 0.013 13.8 5.3 2.2 2 0 0 2 2 2 0 CDC45-like protein AAA_22 PF13401.6 RLN72855.1 - 0.23 11.8 0.7 1.2 9.4 0.1 2.6 2 2 0 2 2 2 0 AAA domain DEAD PF00270.29 RLN72857.1 - 3.2e-07 30.3 0.6 0.014 15.2 0.1 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN72857.1 - 0.03 14.7 0.0 0.11 12.8 0.0 2.0 1 1 0 1 1 1 0 Helicase conserved C-terminal domain CBS PF00571.28 RLN72857.1 - 0.055 13.9 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 CBS domain Dioxygenase_C PF00775.21 RLN72860.1 - 0.00011 21.7 0.1 0.00021 20.8 0.1 1.5 1 0 0 1 1 1 1 Dioxygenase DUF4349 PF14257.6 RLN72860.1 - 0.22 10.9 4.3 0.086 12.3 1.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Dioxygenase_C PF00775.21 RLN72861.1 - 2.7e-06 26.9 0.0 4.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase DUF4349 PF14257.6 RLN72861.1 - 0.066 12.7 0.2 0.13 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Dioxygenase_C PF00775.21 RLN72862.1 - 0.00044 19.7 0.0 0.00093 18.7 0.0 1.5 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_C PF00775.21 RLN72865.1 - 2e-10 40.4 0.2 0.0002 20.8 0.0 2.5 2 0 0 2 2 2 2 Dioxygenase DUF4198 PF10670.9 RLN72865.1 - 0.029 14.8 0.1 8 6.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4198) DUF1084 PF06454.11 RLN72866.1 - 7.2e-07 28.9 10.3 1e-05 25.1 7.6 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1084) DHHA2 PF02833.14 RLN72867.1 - 1.7e-20 73.7 0.1 3.8e-20 72.5 0.0 1.6 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 RLN72867.1 - 3.6e-10 40.0 0.1 7.3e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 DHH family MFS_1_like PF12832.7 RLN72869.1 - 5e-41 140.8 5.0 5.9e-41 140.6 5.0 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RLN72869.1 - 4.4e-14 52.2 30.2 2.9e-08 33.0 8.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 RLN72869.1 - 8.5e-07 28.1 2.3 1.1e-06 27.7 2.3 1.2 1 0 0 1 1 1 1 LacY proton/sugar symporter MFS_3 PF05977.13 RLN72869.1 - 6.9e-05 21.4 1.8 8.6e-05 21.1 1.8 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector Nuc_H_symport PF03825.16 RLN72869.1 - 0.00056 19.0 6.3 0.00072 18.6 6.3 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter PUCC PF03209.15 RLN72869.1 - 0.00081 18.5 0.8 0.00081 18.5 0.8 2.0 2 0 0 2 2 2 1 PUCC protein Caveolin PF01146.17 RLN72869.1 - 3.8 7.5 5.9 2.3 8.2 0.2 2.7 3 0 0 3 3 3 0 Caveolin MFS_1_like PF12832.7 RLN72871.1 - 6.3e-65 219.5 17.7 2.4e-64 217.6 17.7 1.7 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RLN72871.1 - 8.4e-26 90.7 50.8 6e-19 68.2 29.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 RLN72871.1 - 2.9e-13 49.6 21.4 1.8e-12 47.0 21.4 1.9 1 1 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 RLN72871.1 - 3.8e-13 49.0 16.3 1.7e-12 46.9 16.3 2.1 1 1 0 1 1 1 1 LacY proton/sugar symporter MFS_3 PF05977.13 RLN72871.1 - 0.0018 16.8 11.2 0.0018 16.8 11.2 1.7 2 1 0 2 2 2 1 Transmembrane secretion effector LapA_dom PF06305.11 RLN72871.1 - 3.7 7.4 5.8 2.4 8.0 1.7 2.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain UFD1 PF03152.14 RLN72872.1 - 0.031 13.8 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 XRN_N PF03159.18 RLN72872.1 - 1.1 8.6 4.8 1.4 8.2 4.8 1.1 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus EURL PF06937.11 RLN72872.1 - 3.8 6.9 7.3 4.6 6.6 7.3 1.1 1 0 0 1 1 1 0 EURL protein E1-E2_ATPase PF00122.20 RLN72876.1 - 1.5e-37 128.9 3.3 1.2e-36 125.9 1.5 2.0 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_N PF00690.26 RLN72876.1 - 1e-18 66.7 0.0 2.4e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Glyco_hydro_1 PF00232.18 RLN72879.1 - 2e-166 553.9 0.0 2.4e-166 553.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Acyltransferase PF01553.21 RLN72882.1 - 0.038 13.6 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Acyltransferase Fig1 PF12351.8 RLN72882.1 - 0.055 13.4 1.4 0.1 12.5 1.4 1.4 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Presenilin PF01080.17 RLN72882.1 - 0.18 10.6 1.4 0.5 9.1 0.9 1.8 2 0 0 2 2 2 0 Presenilin DUF155 PF02582.14 RLN72883.1 - 2.4e-27 96.2 0.1 4.8e-27 95.2 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 STN1_2 PF09170.10 RLN72883.1 - 0.042 14.1 0.1 0.51 10.5 0.0 2.3 2 0 0 2 2 2 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 SRP68 PF16969.5 RLN72884.1 - 1.1e-128 430.7 29.1 2.3e-128 429.6 29.1 1.5 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 PhaP_Bmeg PF09602.10 RLN72884.1 - 0.58 10.1 4.5 0.45 10.4 0.6 2.3 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) GrpE PF01025.19 RLN72884.1 - 0.78 9.4 9.6 0.7 9.5 0.4 3.6 2 1 1 3 3 3 0 GrpE TPR_2 PF07719.17 RLN72884.1 - 4.3 7.7 12.3 7.3 7.0 2.4 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat GBP PF02263.19 RLN72886.1 - 2e-64 217.4 0.0 3e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 RLN72886.1 - 5.5e-25 88.4 3.9 8e-25 87.8 3.9 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain RHD3 PF05879.12 RLN72886.1 - 0.014 13.6 0.9 0.21 9.7 0.1 2.1 2 0 0 2 2 2 0 Root hair defective 3 GTP-binding protein (RHD3) DUF5039 PF16442.5 RLN72886.1 - 0.054 13.0 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) MMR_HSR1 PF01926.23 RLN72886.1 - 0.074 13.1 0.0 0.28 11.3 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF2383 PF09537.10 RLN72886.1 - 0.097 13.0 3.3 16 5.9 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF2383) DUF3080 PF11279.8 RLN72886.1 - 0.2 10.9 3.2 0.48 9.6 3.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3080) HhH-GPD PF00730.25 RLN72891.1 - 4.3e-14 52.9 0.0 1.4e-06 28.7 0.0 2.5 2 0 0 2 2 2 2 HhH-GPD superfamily base excision DNA repair protein Acetyltransf_1 PF00583.25 RLN72891.1 - 3.1e-12 46.8 0.0 6e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RLN72891.1 - 5.5e-07 29.6 0.1 1.1e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NUDIX_4 PF14815.6 RLN72891.1 - 7e-07 29.2 0.4 2.2e-06 27.6 0.1 2.0 2 0 0 2 2 2 1 NUDIX domain Acetyltransf_7 PF13508.7 RLN72891.1 - 8.1e-07 29.4 0.0 1.6e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN72891.1 - 1.3e-05 25.1 0.0 2.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein HHH PF00633.23 RLN72891.1 - 0.00071 19.3 0.1 0.0018 18.1 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Acetyltransf_8 PF13523.6 RLN72891.1 - 0.0013 18.4 0.0 0.0034 17.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 RLN72891.1 - 0.066 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 RLN72891.1 - 0.11 13.2 0.0 0.37 11.5 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Lon_C PF05362.13 RLN72892.1 - 5.6e-12 45.6 0.1 9e-12 45.0 0.1 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.6 RLN72892.1 - 5.7e-11 42.3 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_25 PF13481.6 RLN72892.1 - 2.6e-06 27.2 0.4 9.4e-06 25.3 0.0 2.1 3 0 0 3 3 3 1 AAA domain ATPase PF06745.13 RLN72892.1 - 3.1e-05 23.4 0.0 0.00061 19.2 0.0 2.2 2 0 0 2 2 2 1 KaiC DnaB_C PF03796.15 RLN72892.1 - 0.007 15.7 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Rubredoxin_2 PF18073.1 RLN72893.1 - 4e-10 39.2 7.0 6.3e-10 38.6 7.0 1.3 1 0 0 1 1 1 1 Rubredoxin metal binding domain NifU PF01106.17 RLN72893.1 - 0.22 11.7 0.5 0.37 11.0 0.5 1.3 1 0 0 1 1 1 0 NifU-like domain DNA_photolyase PF00875.18 RLN72894.1 - 0.082 12.9 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 DNA photolyase Sugar_tr PF00083.24 RLN72906.1 - 7.5e-103 344.8 24.0 8.5e-103 344.6 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN72906.1 - 4.8e-27 94.8 28.7 6.4e-18 64.8 10.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1388 PF07142.12 RLN72906.1 - 0.18 11.8 0.7 0.29 11.1 0.7 1.3 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) DUF3054 PF11255.8 RLN72906.1 - 0.98 10.0 8.4 0.21 12.1 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3054) AAA_8 PF12780.7 RLN72911.1 - 1.7e-101 338.9 0.4 3.3e-100 334.7 0.1 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 RLN72911.1 - 3.6e-73 244.9 4.2 2.7e-72 242.1 0.0 3.3 4 0 0 4 4 3 1 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 RLN72911.1 - 1.2e-27 96.5 0.5 2.5e-26 92.3 0.3 3.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_6 PF12774.7 RLN72911.1 - 3.1e-23 82.3 1.8 2.2e-20 72.9 0.0 3.2 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 RLN72911.1 - 3.5e-21 75.6 0.1 5e-13 49.2 0.0 3.7 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 RLN72911.1 - 1.6e-19 70.0 0.1 5.7e-19 68.2 0.1 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 RLN72911.1 - 8e-08 32.6 0.0 0.0054 17.0 0.0 4.6 5 0 0 5 5 5 1 AAA domain AAA_29 PF13555.6 RLN72911.1 - 6.6e-05 22.6 0.4 0.28 10.9 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain TniB PF05621.11 RLN72911.1 - 0.00011 21.7 0.1 0.33 10.3 0.0 3.4 3 0 0 3 3 3 1 Bacterial TniB protein AAA_23 PF13476.6 RLN72911.1 - 0.00013 22.6 1.9 0.81 10.2 0.0 3.6 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.27 RLN72911.1 - 0.00014 22.4 0.1 2 8.9 0.0 4.2 4 1 0 4 4 4 1 ABC transporter AAA_16 PF13191.6 RLN72911.1 - 0.0002 21.8 0.1 0.034 14.5 0.0 3.8 3 1 1 4 4 4 1 AAA ATPase domain AAA PF00004.29 RLN72911.1 - 0.00025 21.5 0.7 0.0083 16.6 0.0 3.2 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 RLN72911.1 - 0.00032 20.7 0.1 1 9.2 0.0 3.3 3 0 0 3 3 3 1 RsgA GTPase AAA_14 PF13173.6 RLN72911.1 - 0.00033 20.7 0.1 0.014 15.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain Roc PF08477.13 RLN72911.1 - 0.00036 20.7 0.1 0.4 10.9 0.0 3.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 RLN72911.1 - 0.005 16.3 2.3 0.55 9.6 0.0 3.4 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 RLN72911.1 - 0.006 15.7 0.6 5.1 6.1 0.0 3.3 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_30 PF13604.6 RLN72911.1 - 0.015 15.0 0.3 0.73 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 RLN72911.1 - 0.025 14.3 1.1 0.23 11.2 0.0 3.0 4 0 0 4 4 3 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 RLN72911.1 - 0.029 14.5 0.2 3.9 7.6 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 RLN72911.1 - 0.055 13.2 0.1 3.3 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 RLN72911.1 - 0.059 12.6 0.1 9.1 5.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 RLN72911.1 - 0.061 13.3 0.6 1.3 9.1 0.1 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 RLN72911.1 - 0.13 12.2 1.0 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.6 RLN72911.1 - 0.17 11.5 0.4 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 RLN72911.1 - 0.19 11.0 0.8 19 4.5 0.1 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family PduV-EutP PF10662.9 RLN72911.1 - 0.35 10.6 2.8 14 5.4 0.1 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Ank_2 PF12796.7 RLN72913.1 - 2.2e-32 111.5 0.1 2.2e-15 57.0 0.0 5.6 4 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 RLN72913.1 - 3.6e-25 87.3 13.5 9.8e-07 29.0 0.0 9.0 8 0 0 8 8 8 5 Ankyrin repeat TIR_2 PF13676.6 RLN72913.1 - 5.5e-25 88.3 1.0 3.5e-18 66.3 0.1 3.6 3 0 0 3 3 3 3 TIR domain Ank_3 PF13606.6 RLN72913.1 - 2.2e-23 79.8 5.9 0.0004 20.6 0.0 8.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 RLN72913.1 - 5.1e-22 77.7 16.2 2.5e-06 27.6 0.1 7.1 5 1 2 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN72913.1 - 2.4e-21 75.8 9.3 4.4e-07 30.3 0.1 7.7 6 1 2 8 8 8 5 Ankyrin repeats (many copies) TIR PF01582.20 RLN72913.1 - 0.00089 19.1 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 RLN72914.1 - 6.6e-07 30.0 0.0 0.00021 21.9 0.0 2.2 2 0 0 2 2 2 2 TIR domain UDPGT PF00201.18 RLN72915.1 - 1.7e-09 37.0 0.0 2.7e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 RLN72915.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.6 RLN72916.1 - 0.081 12.9 0.2 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase Family 4 DUF4170 PF13773.6 RLN72916.1 - 0.18 11.9 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4170) Cullin PF00888.22 RLN72917.1 - 1e-198 661.9 5.9 1.4e-198 661.4 5.9 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 RLN72917.1 - 3.2e-28 97.6 1.4 1.1e-27 95.8 1.4 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain TUDOR PF00567.24 RLN72918.1 - 1.9e-06 27.9 0.0 0.059 13.4 0.0 2.5 2 1 1 3 3 3 2 Tudor domain SMN PF06003.12 RLN72918.1 - 0.0024 17.2 1.5 0.0027 17.0 0.0 1.7 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) Mpp10 PF04006.12 RLN72918.1 - 0.12 10.8 2.7 0.16 10.4 2.7 1.1 1 0 0 1 1 1 0 Mpp10 protein Ank_4 PF13637.6 RLN72922.1 - 5.9e-08 33.1 1.9 0.027 15.0 0.2 4.6 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN72922.1 - 4.1e-07 30.5 1.6 0.056 14.0 0.1 3.6 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN72922.1 - 8.7e-06 25.7 2.9 4.8 8.1 0.0 5.8 5 1 1 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 RLN72922.1 - 3.6e-05 23.9 3.6 3.3 8.1 0.1 5.2 5 1 1 6 6 6 2 Ankyrin repeats (many copies) CENP-F_leu_zip PF10473.9 RLN72926.1 - 0.0039 17.2 11.4 0.36 10.8 0.2 2.5 2 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PPP4R2 PF09184.11 RLN72926.1 - 5.8 6.4 8.1 8.8 5.8 8.1 1.3 1 0 0 1 1 1 0 PPP4R2 DUF3450 PF11932.8 RLN72926.1 - 9.1 5.5 24.0 0.87 8.8 5.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) PRKCSH-like PF12999.7 RLN72928.1 - 6.2e-33 114.1 3.5 1.2e-32 113.1 3.5 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like DUF4483 PF14825.6 RLN72928.1 - 4.2e-23 81.9 0.0 1.3e-22 80.3 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4483) Ldl_recept_a PF00057.18 RLN72928.1 - 0.7 10.2 15.1 3.4 8.0 6.9 2.6 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A XRN_M PF17846.1 RLN72929.1 - 6.4e-150 500.0 0.0 1.1e-149 499.2 0.0 1.4 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 RLN72929.1 - 1e-96 323.0 0.9 6e-96 320.5 0.0 2.1 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus MIR PF02815.19 RLN72931.1 - 4e-10 39.9 0.1 3.6e-09 36.7 0.1 2.1 1 1 1 2 2 2 2 MIR domain DUF412 PF04217.13 RLN72932.1 - 0.0032 17.4 0.7 0.0066 16.3 0.7 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF412 AMP-binding_C PF13193.6 RLN72932.1 - 0.0091 17.0 0.0 0.033 15.2 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DBP10CT PF08147.12 RLN72933.1 - 3.2e-12 46.5 3.9 3.2e-12 46.5 3.9 2.4 2 0 0 2 2 2 1 DBP10CT (NUC160) domain Herpes_UL17 PF04559.12 RLN72933.1 - 1.8 7.3 4.9 2.8 6.6 4.9 1.2 1 0 0 1 1 1 0 Herpesvirus UL17 protein adh_short PF00106.25 RLN72934.1 - 2.1e-21 76.3 0.0 2.7e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN72934.1 - 4.3e-15 55.9 0.0 5.2e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F-box PF00646.33 RLN72935.1 - 0.0049 16.7 1.4 0.012 15.5 1.4 1.7 1 1 0 1 1 1 1 F-box domain CcmD PF04995.14 RLN72935.1 - 1.2 9.3 4.0 2.5 8.2 0.2 2.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) RRM_1 PF00076.22 RLN72936.1 - 1.9e-12 46.8 0.3 5.2e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RLN72936.1 - 0.019 14.6 0.1 0.031 13.9 0.1 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.6 RLN72936.1 - 0.077 12.6 0.2 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 Sporulation protein family 7 DHDPS PF00701.22 RLN72940.1 - 3.8e-75 252.3 0.0 4.7e-75 252.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family HHH PF00633.23 RLN72940.1 - 0.14 12.1 0.1 0.42 10.6 0.1 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif ABC_tran PF00005.27 RLN72941.1 - 6.3e-06 26.7 0.2 1.1e-05 26.0 0.2 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 RLN72941.1 - 0.0039 16.9 0.9 0.0062 16.3 0.9 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN72941.1 - 0.0083 16.5 0.3 0.015 15.7 0.1 1.5 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 RLN72941.1 - 0.0098 15.2 0.3 0.02 14.2 0.1 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 RLN72941.1 - 0.0099 16.2 0.0 0.021 15.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain DUF3987 PF13148.6 RLN72941.1 - 0.019 14.0 0.3 0.048 12.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Ploopntkinase3 PF18751.1 RLN72941.1 - 0.025 14.5 0.1 0.048 13.6 0.1 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 RsgA_GTPase PF03193.16 RLN72941.1 - 0.043 13.7 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 RLN72941.1 - 0.1 12.6 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 RLN72941.1 - 0.1 12.1 0.5 0.18 11.4 0.2 1.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RLN72941.1 - 0.18 11.7 0.2 0.33 10.9 0.2 1.4 1 0 0 1 1 1 0 NACHT domain DUF87 PF01935.17 RLN72941.1 - 0.19 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_10 PF12846.7 RLN72941.1 - 0.2 10.5 0.1 0.29 10.0 0.1 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.6 RLN72941.1 - 0.22 12.0 0.2 0.47 10.9 0.2 1.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 RLN72941.1 - 0.25 10.5 0.0 1.9 7.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) LPP PF04728.13 RLN72942.1 - 0.35 11.3 5.2 2.5 8.6 0.1 3.6 3 1 0 3 3 3 0 Lipoprotein leucine-zipper FlaC_arch PF05377.11 RLN72942.1 - 9.8 6.7 6.5 94 3.5 0.1 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) LMBR1 PF04791.16 RLN72943.1 - 1.7e-65 221.9 0.3 2e-65 221.7 0.3 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Pkinase_Tyr PF07714.17 RLN72944.1 - 2.3e-45 154.9 0.0 3.3e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN72944.1 - 1.5e-44 152.4 0.0 2.2e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF2048 PF09752.9 RLN72944.1 - 5.2e-36 124.5 0.0 1.3e-21 77.1 0.0 2.3 1 1 1 2 2 2 2 Abhydrolase domain containing 18 Abhydrolase_1 PF00561.20 RLN72944.1 - 4.8e-05 23.1 0.0 0.00016 21.4 0.0 1.9 1 0 0 1 1 1 1 alpha/beta hydrolase fold Kdo PF06293.14 RLN72944.1 - 0.0045 16.4 0.1 0.011 15.1 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Hydrolase_4 PF12146.8 RLN72944.1 - 0.024 13.9 0.2 0.15 11.3 0.2 2.3 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Kinase-like PF14531.6 RLN72944.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Meleagrin PF08189.11 RLN72944.1 - 2.2 8.0 4.5 7.2 6.4 4.5 1.8 1 0 0 1 1 1 0 Meleagrin/Cygnin family Methyltransf_25 PF13649.6 RLN72945.1 - 1.8e-15 57.4 0.0 3.3e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN72945.1 - 7.2e-15 55.4 0.0 1.6e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN72945.1 - 2.6e-12 46.6 0.0 6.9e-12 45.2 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 RLN72945.1 - 6e-12 46.2 0.0 1e-11 45.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN72945.1 - 6.4e-08 32.5 0.0 1.5e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN72945.1 - 1.2e-07 31.8 0.0 1.9e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 RLN72945.1 - 0.027 13.9 0.0 0.09 12.3 0.0 1.9 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain MTS PF05175.14 RLN72945.1 - 0.039 13.5 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_18 PF12847.7 RLN72945.1 - 0.051 13.5 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 RLN72945.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.5 1 1 1 2 2 2 0 Methyltransferase domain bPH_6 PF10756.9 RLN72945.1 - 0.13 12.4 1.6 5.8 7.1 0.1 3.1 2 1 1 3 3 3 0 Bacterial PH domain CMAS PF02353.20 RLN72945.1 - 0.16 11.2 0.0 0.33 10.2 0.0 1.6 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ribosomal_L22 PF00237.19 RLN72946.1 - 0.0085 16.3 0.2 0.012 15.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e NPR3 PF03666.13 RLN72947.1 - 1.4e-44 152.7 0.1 1.6e-31 109.6 0.0 3.9 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 Antimicrobial19 PF08225.11 RLN72947.1 - 0.029 14.0 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 Pseudin antimicrobial peptide Methyltransf_25 PF13649.6 RLN72948.1 - 7.3e-16 58.7 0.0 8.2e-15 55.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN72948.1 - 9.3e-16 58.3 0.0 3.3e-15 56.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN72948.1 - 5.8e-13 48.7 0.0 3e-12 46.4 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 RLN72948.1 - 1.1e-10 42.1 0.0 2.6e-10 40.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN72948.1 - 1.6e-09 37.7 0.0 3.4e-09 36.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN72948.1 - 3.7e-08 33.4 0.0 1e-07 31.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN72948.1 - 0.0098 15.5 0.0 0.083 12.4 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase small domain PSD3 PF07626.11 RLN72948.1 - 0.039 14.4 0.1 17 5.9 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1587) Methyltransf_32 PF13679.6 RLN72948.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RVT_1 PF00078.27 RLN72950.1 - 1.7e-06 27.7 0.0 3.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AHSP PF09236.10 RLN72950.1 - 0.015 15.7 0.1 16 6.1 0.0 3.7 3 0 0 3 3 3 0 Alpha-haemoglobin stabilising protein Syntaxin_2 PF14523.6 RLN72950.1 - 1.7 9.0 5.1 20 5.7 0.9 3.2 2 0 0 2 2 2 0 Syntaxin-like protein Chordopox_A13L PF05961.11 RLN72954.1 - 0.0043 17.3 0.7 0.005 17.1 0.7 1.4 1 1 0 1 1 1 1 Chordopoxvirus A13L protein Myc_target_1 PF15179.6 RLN72954.1 - 0.03 14.2 0.0 0.03 14.2 0.0 1.0 1 0 0 1 1 1 0 Myc target protein 1 CcmD PF04995.14 RLN72954.1 - 0.05 13.7 0.9 0.071 13.2 0.9 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Gram_pos_anchor PF00746.21 RLN72954.1 - 0.05 13.5 0.1 0.085 12.8 0.1 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF485 PF04341.12 RLN72954.1 - 0.076 13.0 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF485 VEGFR-2_TMD PF17988.1 RLN72954.1 - 0.088 12.3 1.8 0.15 11.5 1.8 1.4 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain SLATT_6 PF18169.1 RLN72954.1 - 0.098 12.3 0.0 12 5.5 0.0 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 LapA_dom PF06305.11 RLN72954.1 - 0.1 12.4 0.2 0.13 12.1 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF5411 PF17424.2 RLN72954.1 - 0.13 12.3 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5411) DUF4381 PF14316.6 RLN72954.1 - 0.13 12.4 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) THOC2_N PF16134.5 RLN72958.1 - 4e-60 204.2 1.4 5.5e-56 190.5 1.4 3.1 1 1 0 1 1 1 1 THO complex subunit 2 N-terminus Thoc2 PF11732.8 RLN72958.1 - 3.2e-29 100.8 0.1 7.8e-29 99.6 0.1 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Tho2 PF11262.8 RLN72958.1 - 3.1e-06 26.6 0.3 1.5e-05 24.3 0.2 2.0 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Motilin_assoc PF04643.12 RLN72962.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide PP2C PF00481.21 RLN72967.1 - 2.3e-48 165.1 0.2 3.1e-47 161.4 0.0 2.4 2 1 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 RLN72967.1 - 1.5e-05 24.8 0.4 5.1e-05 23.0 0.0 2.0 1 1 1 2 2 2 1 Protein phosphatase 2C U3_snoRNA_assoc PF08297.11 RLN72967.1 - 0.1 13.3 1.0 0.25 12.1 1.0 1.7 1 0 0 1 1 1 0 U3 snoRNA associated MRP-L20 PF12824.7 RLN72968.1 - 0.0029 17.8 2.3 0.013 15.7 1.9 2.3 1 1 1 2 2 2 1 Mitochondrial ribosomal protein subunit L20 NOA36 PF06524.12 RLN72968.1 - 0.87 8.9 11.2 1.8 7.8 11.2 1.7 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 RLN72968.1 - 4.5 5.2 7.5 1 7.4 4.6 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Con-6 PF10346.9 RLN72968.1 - 5.9 7.0 5.9 1.3 9.2 1.5 2.2 2 0 0 2 2 2 0 Conidiation protein 6 JmjC PF02373.22 RLN72974.1 - 1.2e-42 145.0 0.4 2.1e-42 144.2 0.4 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.16 RLN72974.1 - 2.1e-13 50.4 7.7 2.1e-13 50.4 7.7 2.7 2 0 0 2 2 2 1 C5HC2 zinc finger PLU-1 PF08429.11 RLN72974.1 - 2.2e-13 50.1 9.0 4.2e-07 29.4 0.1 3.9 4 1 1 5 5 5 2 PLU-1-like protein PHD PF00628.29 RLN72974.1 - 6.3e-12 45.2 33.8 3.9e-08 33.1 8.6 3.4 3 0 0 3 3 3 2 PHD-finger PHD_4 PF16866.5 RLN72974.1 - 1.7 8.8 16.7 0.8 9.8 3.0 2.9 1 1 1 2 2 2 0 PHD-finger C1_1 PF00130.22 RLN72974.1 - 7.3 6.6 35.5 0.029 14.3 3.3 4.1 2 2 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Myb_DNA-bind_4 PF13837.6 RLN72978.1 - 1.5 9.2 6.9 0.38 11.2 0.2 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Sugar_tr PF00083.24 RLN72979.1 - 1.1e-40 139.9 5.8 1.4e-40 139.6 5.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN72979.1 - 1.1e-17 64.0 10.6 1.3e-17 63.8 10.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 RLN72979.1 - 0.0037 15.7 2.4 0.0045 15.5 2.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CytB6-F_Fe-S PF08802.10 RLN72979.1 - 0.15 12.1 8.8 2.5 8.2 1.3 2.5 1 1 1 2 2 2 0 Cytochrome B6-F complex Fe-S subunit LRR_8 PF13855.6 RLN72980.1 - 1.8e-05 24.4 13.0 0.08 12.7 0.0 6.5 6 0 0 6 6 6 2 Leucine rich repeat LRR_6 PF13516.6 RLN72980.1 - 8.7e-05 22.3 16.6 0.44 10.7 0.0 7.3 9 0 0 9 9 9 2 Leucine Rich repeat LRR_1 PF00560.33 RLN72980.1 - 0.0013 19.0 14.1 2.6 8.9 0.0 6.7 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_4 PF12799.7 RLN72980.1 - 0.22 12.0 19.5 2.8 8.5 0.1 6.2 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) MULE PF10551.9 RLN72981.1 - 2.7e-12 46.9 0.0 4.8e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Calponin PF00402.18 RLN72981.1 - 0.011 15.4 0.1 0.023 14.3 0.1 1.5 1 0 0 1 1 1 0 Calponin family repeat GIIM PF08388.11 RLN72981.1 - 0.047 13.7 0.6 0.1 12.6 0.6 1.5 1 0 0 1 1 1 0 Group II intron, maturase-specific domain Dimer_Tnp_hAT PF05699.14 RLN72982.1 - 4.2e-06 26.5 0.1 9.3e-06 25.4 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DENN PF02141.21 RLN72991.1 - 3.9e-32 111.7 1.7 1.7e-31 109.7 1.7 2.1 1 1 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 RLN72991.1 - 0.00029 20.8 0.7 0.00072 19.5 0.7 1.7 1 0 0 1 1 1 1 dDENN domain RGS PF00615.19 RLN72991.1 - 0.0078 16.5 1.2 1.2 9.5 0.9 2.9 2 1 0 2 2 2 1 Regulator of G protein signaling domain SR-25 PF10500.9 RLN72991.1 - 5.9 6.4 37.0 2.1 7.9 2.3 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein UPF0052 PF01933.18 RLN72992.1 - 1.3e-79 267.5 0.5 1.5e-71 241.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family UPF0052 HAD_2 PF13419.6 RLN72992.1 - 1.1e-05 25.6 0.0 2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RLN72992.1 - 0.001 19.4 0.0 0.0022 18.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pox_A_type_inc PF04508.12 RLN72994.1 - 9.9 6.2 10.6 2.3 8.2 0.1 5.1 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Peptidase_S9 PF00326.21 RLN72997.1 - 1.6e-05 24.5 0.0 0.00013 21.5 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 RLN72997.1 - 0.00047 20.8 1.5 0.00084 20.0 1.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN72997.1 - 0.0006 19.2 0.0 0.0037 16.6 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 RLN72997.1 - 0.0097 15.4 2.2 0.68 9.4 0.0 2.6 3 0 0 3 3 3 2 Esterase PHB depolymerase Abhydrolase_1 PF00561.20 RLN72997.1 - 0.041 13.5 0.0 0.76 9.4 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF3209 PF11483.8 RLN72997.1 - 0.086 13.3 0.1 0.17 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) Pkinase_Tyr PF07714.17 RLN73001.1 - 1.2e-12 47.7 0.0 8.4e-12 44.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RLN73001.1 - 8e-11 41.8 0.0 1.8e-07 30.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain DUF2946 PF11162.8 RLN73001.1 - 0.12 13.0 0.0 0.19 12.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) Glyco_hydro_31 PF01055.26 RLN73002.1 - 2.4e-137 458.7 1.6 3e-137 458.4 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 RLN73002.1 - 2.8e-19 69.2 0.3 1.4e-18 66.9 0.0 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like ABC_membrane PF00664.23 RLN73003.1 - 1.9e-37 129.4 0.0 2.6e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ECF_trnsprt PF12822.7 RLN73003.1 - 0.014 15.5 1.1 0.059 13.5 0.1 2.1 2 0 0 2 2 2 0 ECF transporter, substrate-specific component Sec7 PF01369.20 RLN73006.1 - 1.3e-63 214.1 0.0 2.5e-63 213.1 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain DUF1981 PF09324.10 RLN73006.1 - 1.6e-28 98.4 0.0 6.8e-27 93.2 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) Mon2_C PF16206.5 RLN73006.1 - 3.8e-05 22.0 0.1 0.00033 19.0 0.0 2.0 2 0 0 2 2 2 1 C-terminal region of Mon2 protein Glyco_hydro_3_C PF01915.22 RLN73010.1 - 3e-42 144.9 0.2 1.6e-41 142.5 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 RLN73010.1 - 3.7e-25 89.0 0.0 7.4e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 RLN73010.1 - 2.2e-14 53.3 0.1 4.4e-14 52.4 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Beta_propel PF09826.9 RLN73012.1 - 0.12 11.2 0.1 0.15 10.9 0.1 1.0 1 0 0 1 1 1 0 Beta propeller domain zf-RING_2 PF13639.6 RLN73018.1 - 1.4e-11 44.5 9.6 3.8e-11 43.1 9.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RLN73018.1 - 3.4e-07 30.0 7.8 9.2e-07 28.6 7.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN73018.1 - 4.1e-07 29.6 2.9 9.8e-07 28.4 2.9 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RLN73018.1 - 9.1e-07 28.6 9.1 2.2e-06 27.4 9.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN73018.1 - 1.7e-06 27.7 5.5 4e-06 26.6 5.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN73018.1 - 4.7e-06 26.8 10.5 1.9e-05 24.8 10.5 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RLN73018.1 - 6.2e-06 26.1 4.1 6.2e-06 26.1 4.1 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN73018.1 - 7.3e-06 25.8 6.5 1.9e-05 24.5 6.5 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RLN73018.1 - 0.00015 21.6 10.4 0.0062 16.4 3.2 2.5 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 RLN73018.1 - 0.00076 19.1 7.2 0.0019 17.8 7.2 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 RLN73018.1 - 0.0063 16.5 3.8 0.0063 16.5 3.8 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 RLN73018.1 - 0.34 10.7 5.7 0.97 9.3 5.7 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Vps39_2 PF10367.9 RLN73018.1 - 0.58 10.6 5.0 0.36 11.3 1.4 2.2 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 RINGv PF12906.7 RLN73018.1 - 0.88 9.7 7.9 2.7 8.2 7.9 1.9 1 0 0 1 1 1 0 RING-variant domain Dimer_Tnp_hAT PF05699.14 RLN73019.1 - 0.088 12.6 0.1 0.25 11.1 0.1 1.8 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region zf-CCCH PF00642.24 RLN73020.1 - 3.9e-07 29.8 24.7 0.0057 16.5 5.3 4.7 3 2 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 RLN73020.1 - 0.022 15.5 13.1 0.33 11.7 0.3 3.4 2 1 1 3 3 3 0 Torus domain zf_CCCH_4 PF18345.1 RLN73020.1 - 4.6 7.4 26.9 4.4 7.5 6.4 4.8 4 1 0 4 4 4 0 Zinc finger domain Dimer_Tnp_hAT PF05699.14 RLN73028.1 - 0.00063 19.5 0.1 0.0013 18.4 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Ank_2 PF12796.7 RLN73043.1 - 8.1e-34 116.1 12.8 2.5e-07 31.2 0.4 6.6 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN73043.1 - 4.5e-30 103.6 22.2 7.3e-07 29.6 0.1 10.6 6 3 5 12 12 12 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN73043.1 - 4e-22 78.0 22.8 0.006 16.9 0.0 12.6 4 3 10 14 14 14 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN73043.1 - 2.7e-11 42.6 16.4 1.7 9.4 0.0 12.2 12 1 2 14 14 14 1 Ankyrin repeat Ank PF00023.30 RLN73043.1 - 0.0035 17.7 15.3 8.7 7.0 0.1 9.2 6 2 1 7 7 7 1 Ankyrin repeat Ndc80_HEC PF03801.13 RLN73043.1 - 0.01 15.5 0.1 0.76 9.4 0.0 3.5 4 1 0 4 4 4 0 HEC/Ndc80p family Il2rg PF15874.5 RLN73043.1 - 0.082 13.2 0.0 30 5.0 0.0 3.7 4 0 0 4 4 4 0 Putative Interleukin 2 receptor, gamma chain DUF3322 PF11795.8 RLN73043.1 - 0.21 11.6 8.7 3 7.8 0.0 4.4 4 2 3 7 7 7 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Cas9_Topo PF17894.1 RLN73043.1 - 1.4 9.0 4.3 9.2 6.4 0.2 4.0 5 0 0 5 5 5 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 Mannosyl_trans2 PF04188.13 RLN73044.1 - 9.5e-60 203.1 18.5 2.8e-59 201.6 18.5 1.8 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) PMT_2 PF13231.6 RLN73044.1 - 6.5e-06 26.5 6.1 2.3e-05 24.7 6.1 2.0 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase GWT1 PF06423.12 RLN73044.1 - 0.21 11.7 2.2 0.55 10.3 0.0 2.4 2 1 0 2 2 2 0 GWT1 ABC2_membrane_3 PF12698.7 RLN73045.1 - 1.5e-21 76.9 33.9 1.7e-20 73.5 33.9 2.0 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 RLN73045.1 - 0.00035 20.2 16.6 0.00035 20.2 16.6 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 RLN73045.1 - 0.18 11.2 30.9 0.15 11.5 24.7 2.6 2 1 0 2 2 2 0 ABC-2 type transporter ABC2_membrane_2 PF12679.7 RLN73045.1 - 3.1 7.0 22.0 0.76 9.0 16.8 1.9 2 1 1 3 3 3 0 ABC-2 family transporter protein PHD PF00628.29 RLN73046.1 - 3.3e-17 62.1 24.5 2.8e-10 39.9 7.8 2.4 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 RLN73046.1 - 1.1e-07 31.2 12.5 0.00028 20.4 2.7 2.4 2 0 0 2 2 2 2 PHD-finger zf-CSL PF05207.13 RLN73046.1 - 0.0027 17.4 2.9 0.0027 17.4 2.9 2.6 2 0 0 2 2 2 1 CSL zinc finger C1_1 PF00130.22 RLN73046.1 - 0.1 12.5 14.2 0.049 13.5 2.1 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 RLN73046.1 - 0.12 12.5 19.5 3.7 7.7 6.8 2.6 1 1 1 2 2 2 0 PHD-finger Ribosomal_S27e PF01667.17 RLN73046.1 - 2.4 8.0 4.8 2.3 8.0 0.5 2.7 3 0 0 3 3 3 0 Ribosomal protein S27 zf-RING_9 PF13901.6 RLN73046.1 - 3.6 7.5 15.2 5 7.0 2.5 2.3 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon GTP_EFTU PF00009.27 RLN73047.1 - 3.9e-36 124.4 1.1 1.2e-34 119.6 1.1 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 RLN73047.1 - 6.6e-21 74.4 1.2 1.4e-20 73.4 0.3 1.9 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 RLN73047.1 - 4.6e-10 39.6 0.1 1.1e-09 38.4 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RLN73047.1 - 0.0007 19.5 0.5 0.19 11.6 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 RLN73047.1 - 0.0032 16.9 0.0 0.007 15.8 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit IF2_N PF04760.15 RLN73047.1 - 0.0035 17.1 0.0 0.011 15.6 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Dynamin_N PF00350.23 RLN73047.1 - 0.0068 16.5 0.1 0.1 12.6 0.0 2.3 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.18 RLN73047.1 - 0.016 14.8 0.3 0.066 12.7 0.3 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 RLN73047.1 - 0.017 14.8 0.0 0.25 11.1 0.0 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 RLN73047.1 - 0.081 12.7 0.0 0.37 10.5 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Thioredoxin_8 PF13905.6 RLN73048.1 - 7.9e-18 64.6 0.0 1.7e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA PF00627.31 RLN73048.1 - 0.0026 17.6 0.3 0.0072 16.2 0.3 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Thioredoxin_2 PF13098.6 RLN73048.1 - 0.022 15.2 0.0 0.077 13.5 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like domain AhpC-TSA PF00578.21 RLN73048.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family TetR_C_15 PF17918.1 RLN73048.1 - 0.19 12.5 1.3 70 4.2 0.0 3.7 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DEAD PF00270.29 RLN73053.1 - 2.4e-43 148.0 0.0 4.4e-43 147.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN73053.1 - 6.1e-26 91.0 0.0 2.8e-25 88.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN73053.1 - 0.00015 21.8 0.0 0.0003 20.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 RLN73053.1 - 0.012 15.0 0.0 0.03 13.7 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Choline_transpo PF04515.12 RLN73054.1 - 4.3e-50 170.8 29.8 4.3e-50 170.8 29.8 2.3 2 0 0 2 2 2 1 Plasma-membrane choline transporter PX PF00787.24 RLN73054.1 - 0.0019 18.2 0.3 0.0033 17.4 0.3 1.4 1 0 0 1 1 1 1 PX domain SHR3_chaperone PF08229.11 RLN73054.1 - 0.17 10.8 3.1 0.19 10.7 0.2 2.1 1 1 1 2 2 2 0 ER membrane protein SH3 Phosducin PF02114.16 RLN73055.1 - 3.4e-13 49.1 0.2 5.1e-09 35.5 0.0 2.3 1 1 1 2 2 2 2 Phosducin Arf PF00025.21 RLN73056.1 - 7.2e-33 113.5 0.0 4.4e-32 110.9 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RLN73056.1 - 6.8e-09 36.0 0.0 1.6e-08 34.8 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RLN73056.1 - 8.9e-08 31.9 0.0 1.8e-07 30.9 0.0 1.5 2 0 0 2 2 2 1 Ras family GTP_EFTU PF00009.27 RLN73056.1 - 2.4e-06 27.2 0.0 1.2e-05 25.0 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 RLN73056.1 - 9.4e-05 21.9 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 RLN73056.1 - 0.00024 20.4 0.2 0.016 14.4 0.0 2.6 2 1 1 3 3 3 1 G-protein alpha subunit MMR_HSR1 PF01926.23 RLN73056.1 - 0.00054 20.0 0.0 0.0014 18.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 RLN73056.1 - 0.014 14.8 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit cobW PF02492.19 RLN73056.1 - 0.09 12.4 0.0 4.2 6.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain zf-CCCH PF00642.24 RLN73057.1 - 2.1e-14 53.0 7.3 5.8e-07 29.3 0.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RLN73057.1 - 6e-10 38.9 11.9 7.6e-05 22.6 1.7 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-met PF12874.7 RLN73057.1 - 1.1e-08 35.1 2.4 4.5e-07 30.1 0.3 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-CCCH_4 PF18044.1 RLN73057.1 - 1.7e-08 34.1 8.9 0.00014 21.6 1.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-C2H2_jaz PF12171.8 RLN73057.1 - 1.4e-07 31.6 8.8 8.6e-07 29.1 0.2 2.9 3 0 0 3 3 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 RLN73057.1 - 1.2e-06 28.8 5.9 0.0029 17.9 4.2 2.6 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 RLN73057.1 - 0.00044 20.6 2.4 0.035 14.6 0.3 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type Torus PF16131.5 RLN73057.1 - 0.0021 18.7 16.2 0.012 16.3 4.6 2.9 2 1 1 3 3 2 2 Torus domain zf-C2H2_4 PF13894.6 RLN73057.1 - 0.0092 16.7 0.8 0.19 12.6 0.1 3.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-CCCH_2 PF14608.6 RLN73057.1 - 0.11 13.1 10.0 0.35 11.4 1.5 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 RLN73057.1 - 0.22 11.8 11.1 1.2 9.3 6.9 3.2 1 1 1 2 2 2 0 Zinc-finger containing family zf-H2C2_2 PF13465.6 RLN73057.1 - 0.44 11.1 0.1 0.44 11.1 0.1 3.7 4 0 0 4 4 4 0 Zinc-finger double domain Sporozoite_P67 PF05642.11 RLN73057.1 - 0.55 8.2 5.2 0.72 7.9 5.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Striatin PF08232.12 RLN73057.1 - 2.6 8.6 14.3 1.1 9.9 7.7 2.3 2 0 0 2 2 2 0 Striatin family DUF1840 PF08895.11 RLN73057.1 - 5.6 7.4 10.4 0.1 12.9 2.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) RXT2_N PF08595.11 RLN73057.1 - 6.2 6.8 9.6 4.1 7.4 7.5 1.8 1 1 1 2 2 2 0 RXT2-like, N-terminal ATP-synt_D PF01813.17 RLN73058.1 - 9.4e-29 100.6 0.4 9.4e-29 100.6 0.4 1.5 2 0 0 2 2 2 1 ATP synthase subunit D DUF573 PF04504.14 RLN73058.1 - 0.23 12.1 1.3 0.67 10.6 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function, DUF573 RabGAP-TBC PF00566.18 RLN73059.1 - 0.076 12.7 0.0 9.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Rab-GTPase-TBC domain MyTH4 PF00784.17 RLN73061.1 - 8.6e-22 77.7 0.1 1.8e-21 76.6 0.1 1.5 1 0 0 1 1 1 1 MyTH4 domain FERM_M PF00373.18 RLN73061.1 - 0.00024 21.5 0.0 0.00084 19.7 0.0 1.9 2 0 0 2 2 2 1 FERM central domain IRS PF02174.17 RLN73061.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 PTB domain (IRS-1 type) FERM_N PF09379.10 RLN73061.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 FERM N-terminal domain SNF2_N PF00176.23 RLN73068.1 - 2.2e-48 164.7 0.0 4.1e-48 163.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN73068.1 - 0.0044 17.4 0.0 0.035 14.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 RLN73068.1 - 0.48 9.6 2.5 1.6 7.9 0.0 2.7 3 0 0 3 3 3 0 ERCC3/RAD25/XPB C-terminal helicase Pkinase PF00069.25 RLN73072.1 - 2.2e-47 161.6 0.0 2.9e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN73072.1 - 3.2e-45 154.4 0.0 4.2e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase TMEM154 PF15102.6 RLN73072.1 - 0.0033 17.3 0.0 0.0059 16.5 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family Kdo PF06293.14 RLN73072.1 - 0.0034 16.8 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RLN73072.1 - 0.0054 15.7 0.0 0.047 12.6 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain EphA2_TM PF14575.6 RLN73072.1 - 0.035 15.0 0.2 0.48 11.3 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain APH PF01636.23 RLN73072.1 - 0.043 13.7 0.0 0.32 10.9 0.0 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family Phage_holin_2_1 PF04971.12 RLN73072.1 - 0.074 13.1 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Bacteriophage P21 holin S Pkinase_fungal PF17667.1 RLN73072.1 - 0.1 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Adeno_E3_CR2 PF02439.15 RLN73072.1 - 0.11 12.3 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.10 RLN73072.1 - 3.9 7.0 5.9 1.1 8.7 2.3 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Sugar_tr PF00083.24 RLN73076.1 - 1.5e-52 179.0 27.8 2.3e-52 178.4 27.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN73076.1 - 1.3e-30 106.5 50.0 1.1e-25 90.3 29.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 RLN73076.1 - 2.4e-06 27.1 7.5 2.4e-06 27.1 7.5 2.0 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Rsa3 PF14615.6 RLN73080.1 - 2.8e-15 55.6 0.5 5.5e-15 54.7 0.1 1.7 2 0 0 2 2 2 1 Ribosome-assembly protein 3 DUF2052 PF09747.9 RLN73080.1 - 0.028 14.6 7.2 0.043 14.0 7.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Pribosyltran PF00156.27 RLN73080.1 - 0.073 12.6 0.2 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Cwf_Cwc_15 PF04889.12 RLN73080.1 - 0.27 10.9 6.4 0.34 10.6 6.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DOT1 PF08123.13 RLN73081.1 - 4.4e-07 29.6 0.0 8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 ThiF PF00899.21 RLN73082.1 - 2.1e-60 204.1 0.2 3.5e-60 203.4 0.2 1.3 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 RLN73082.1 - 5.7e-11 42.9 0.0 1.1e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.20 RLN73082.1 - 0.014 15.4 0.1 0.049 13.7 0.0 1.7 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 RLN73082.1 - 0.031 14.5 1.4 0.2 11.9 1.4 2.3 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PglD_N PF17836.1 RLN73082.1 - 0.065 13.9 0.0 0.19 12.4 0.0 1.8 1 0 0 1 1 1 0 PglD N-terminal domain Mto2_bdg PF12808.7 RLN73082.1 - 1 9.7 6.9 0.24 11.7 2.2 2.1 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region F-box-like PF12937.7 RLN73083.1 - 2.8e-08 33.5 0.2 1.1e-07 31.6 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RLN73083.1 - 4.2e-06 26.5 0.1 1.1e-05 25.1 0.1 1.7 1 0 0 1 1 1 1 F-box domain Kinesin PF00225.23 RLN73084.1 - 3.1e-70 236.7 0.0 6.1e-70 235.8 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain DENN PF02141.21 RLN73084.1 - 6.7e-33 114.2 0.2 1.7e-30 106.4 0.8 2.5 1 1 0 2 2 2 1 DENN (AEX-3) domain WD40 PF00400.32 RLN73084.1 - 9.1e-24 83.3 13.2 0.00013 22.7 0.0 8.9 8 0 0 8 8 8 6 WD domain, G-beta repeat Microtub_bd PF16796.5 RLN73084.1 - 1.3e-15 57.6 0.0 2.7e-14 53.3 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding uDENN PF03456.18 RLN73084.1 - 4.5e-12 46.5 2.3 5.9e-12 46.2 0.2 2.5 2 0 0 2 2 2 1 uDENN domain Nup160 PF11715.8 RLN73084.1 - 0.02 13.6 0.1 4.8 5.7 0.0 3.0 3 0 0 3 3 3 0 Nucleoporin Nup120/160 SPA PF08616.10 RLN73084.1 - 0.02 14.8 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 Stabilization of polarity axis Ank_2 PF12796.7 RLN73085.1 - 8.3e-22 77.6 0.7 3.2e-07 30.8 0.0 3.9 3 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN73085.1 - 4.3e-15 55.9 0.2 0.00023 21.6 0.0 5.5 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN73085.1 - 3e-14 51.7 0.7 0.0019 18.6 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 RLN73085.1 - 2.5e-10 40.3 3.3 0.69 10.5 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 RLN73085.1 - 1e-09 38.4 0.9 0.16 12.3 0.1 4.3 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Pkinase PF00069.25 RLN73087.1 - 1.2e-62 211.7 0.0 1.7e-62 211.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN73087.1 - 1.2e-42 146.0 0.0 1.7e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase IFT57 PF10498.9 RLN73087.1 - 3.5e-32 111.8 0.0 5.5e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Kinase-like PF14531.6 RLN73087.1 - 7.5e-08 32.0 0.2 1.7e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 RLN73087.1 - 9.2e-05 21.4 0.5 0.00069 18.5 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 RLN73087.1 - 0.006 16.5 1.0 0.029 14.3 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN73087.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 RLN73087.1 - 0.014 15.1 0.3 2.1 7.9 0.1 2.4 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF1681 PF07933.14 RLN73088.1 - 9.6e-40 135.7 0.0 1.3e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) SLY PF12485.8 RLN73088.1 - 0.076 13.7 1.0 0.12 13.0 1.0 1.2 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein Patatin PF01734.22 RLN73089.1 - 7.4e-25 88.3 0.1 1.7e-24 87.2 0.1 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase cNMP_binding PF00027.29 RLN73089.1 - 2.8e-21 75.4 0.5 8.1e-09 35.4 0.0 4.0 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain DUF2076 PF09849.9 RLN73089.1 - 0.15 12.1 0.4 0.3 11.1 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) NAGLU_C PF12972.7 RLN73089.1 - 0.29 10.6 0.8 0.56 9.7 0.8 1.4 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain Pkinase PF00069.25 RLN73090.1 - 6.8e-64 215.8 0.0 1.3e-63 214.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN73090.1 - 4.2e-33 114.7 0.0 7.1e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN73090.1 - 3.5e-06 26.0 1.3 3.8e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase PH PF00169.29 RLN73090.1 - 2.4e-05 24.8 0.0 7.4e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 PH domain EF-hand_1 PF00036.32 RLN73090.1 - 0.0025 17.3 0.1 0.0077 15.7 0.1 1.9 1 0 0 1 1 1 1 EF hand Kdo PF06293.14 RLN73090.1 - 0.0027 17.1 0.2 0.0059 16.0 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_7 PF13499.6 RLN73090.1 - 0.027 14.9 2.0 0.11 13.0 0.6 2.7 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 RLN73090.1 - 0.041 13.8 0.1 0.2 11.7 0.1 2.2 2 0 0 2 2 2 0 EF-hand domain Caleosin PF05042.13 RLN73090.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Caleosin related protein PTR2 PF00854.21 RLN73091.1 - 1.2e-55 188.9 7.4 3.6e-55 187.4 7.4 1.8 1 1 0 1 1 1 1 POT family WW PF00397.26 RLN73091.1 - 1.2e-21 76.4 40.4 1.4e-05 25.1 0.6 6.6 6 0 0 6 6 6 5 WW domain LRR_6 PF13516.6 RLN73091.1 - 1.6e-05 24.6 5.0 0.22 11.7 0.0 3.8 3 0 0 3 3 3 2 Leucine Rich repeat IQ PF00612.27 RLN73091.1 - 6.2e-05 22.4 36.0 0.025 14.4 6.5 6.8 7 0 0 7 7 7 3 IQ calmodulin-binding motif LRR_4 PF12799.7 RLN73091.1 - 0.24 11.9 4.9 4 8.0 0.1 2.6 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) OCRE PF17780.1 RLN73091.1 - 2.1 8.5 15.9 7.6 6.7 3.4 4.0 3 2 0 3 3 3 0 OCRE domain PHD PF00628.29 RLN73093.1 - 7.4e-08 32.2 7.2 1.5e-07 31.2 7.2 1.5 1 0 0 1 1 1 1 PHD-finger FANCL_C PF11793.8 RLN73093.1 - 0.013 15.7 1.6 0.029 14.5 1.6 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain ZF-HD_dimer PF04770.12 RLN73093.1 - 0.028 14.8 2.2 0.11 12.8 2.2 2.1 1 1 0 1 1 1 0 ZF-HD protein dimerisation region Cwf_Cwc_15 PF04889.12 RLN73093.1 - 1.4 8.6 23.7 1.5 8.5 5.0 2.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RINGv PF12906.7 RLN73093.1 - 4.7 7.4 6.7 8.5 6.6 6.7 1.4 1 0 0 1 1 1 0 RING-variant domain RCC1 PF00415.18 RLN73099.1 - 1.6e-45 153.5 10.7 1.5e-10 41.5 0.0 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN73099.1 - 2.6e-20 71.7 24.3 9.1e-09 34.9 0.4 5.9 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat PA PF02225.22 RLN73099.1 - 3.3e-05 23.8 0.2 0.4 10.7 0.0 2.7 2 0 0 2 2 2 2 PA domain HA PF03457.14 RLN73100.1 - 3e-32 110.8 9.6 2.5e-05 24.5 0.0 8.0 8 1 0 8 8 8 7 Helicase associated domain TPR_7 PF13176.6 RLN73100.1 - 0.085 12.9 0.2 0.51 10.5 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PG_binding_2 PF08823.11 RLN73100.1 - 0.11 12.8 0.7 5.4 7.4 0.0 3.3 4 0 0 4 4 4 0 Putative peptidoglycan binding domain Aldedh PF00171.22 RLN73101.1 - 3.3e-108 362.2 1.2 2.8e-70 237.1 0.4 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Gly-zipper_YMGG PF13441.6 RLN73101.1 - 0.069 12.9 4.5 0.19 11.5 4.5 1.8 1 0 0 1 1 1 0 YMGG-like Gly-zipper LRR_8 PF13855.6 RLN73102.1 - 3.2e-31 106.9 23.5 3.7e-07 29.8 1.8 7.1 4 2 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 RLN73102.1 - 6.9e-28 96.2 14.2 5.9e-06 26.5 0.2 8.4 7 1 1 8 8 8 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN73102.1 - 5.1e-08 32.6 5.5 0.0022 17.5 0.5 3.5 2 1 1 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 RLN73102.1 - 3.2e-05 23.6 13.0 1.2 9.3 0.1 8.0 7 0 0 7 7 7 2 Leucine Rich repeat ubiquitin PF00240.23 RLN73102.1 - 6.9e-05 22.5 0.0 0.0002 21.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family LRR_1 PF00560.33 RLN73102.1 - 0.0046 17.3 22.7 11 7.0 0.1 9.8 9 3 0 9 9 9 1 Leucine Rich Repeat Ubiquitin_2 PF14560.6 RLN73102.1 - 0.089 13.3 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain DDHD PF02862.17 RLN73102.1 - 0.4 10.8 2.6 0.75 9.9 2.6 1.4 1 0 0 1 1 1 0 DDHD domain FYVE PF01363.21 RLN73103.1 - 7.8e-12 45.2 11.1 2.4e-11 43.6 11.1 1.9 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 RLN73103.1 - 3.5e-06 27.7 0.0 8.5e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 GAF domain FYVE_2 PF02318.16 RLN73103.1 - 0.01 16.0 5.7 0.028 14.6 5.7 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger GLE1 PF07817.13 RLN73104.1 - 1.8e-34 119.1 0.0 4.1e-34 117.9 0.0 1.6 1 0 0 1 1 1 1 GLE1-like protein GRP PF07172.11 RLN73104.1 - 0.0019 18.8 11.6 0.0019 18.8 11.6 3.1 2 1 0 2 2 2 1 Glycine rich protein family TFIIA PF03153.13 RLN73104.1 - 3.6 7.5 21.4 5.4 6.9 21.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.7 RLN73104.1 - 4.1 5.4 13.1 5 5.1 13.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ribosomal_S27e PF01667.17 RLN73105.1 - 2.2e-28 97.7 4.3 2.6e-28 97.5 4.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-CSL PF05207.13 RLN73105.1 - 0.032 14.0 1.9 0.057 13.2 1.9 1.5 1 1 0 1 1 1 0 CSL zinc finger RXLR PF16810.5 RLN73107.1 - 0.069 13.6 0.1 0.077 13.4 0.1 1.2 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Zip PF02535.22 RLN73108.1 - 5e-12 45.7 4.4 5e-12 45.7 4.4 2.4 1 1 1 3 3 3 3 ZIP Zinc transporter CbtB PF09489.10 RLN73108.1 - 0.033 14.3 1.2 0.033 14.3 1.2 3.0 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) DMRL_synthase PF00885.19 RLN73109.1 - 5.5e-16 58.7 0.0 6.8e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase NAD_binding_10 PF13460.6 RLN73120.1 - 9.6e-14 51.7 0.0 3.9e-13 49.7 0.0 2.0 2 1 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 RLN73120.1 - 2.5e-13 50.2 0.0 2.1e-12 47.1 0.0 2.0 1 1 1 2 2 2 1 NmrA-like family LpxI_N PF17930.1 RLN73120.1 - 0.0009 19.1 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 LpxI N-terminal domain Glyco_transf_4 PF13439.6 RLN73120.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Sacchrp_dh_NADP PF03435.18 RLN73120.1 - 0.034 14.4 0.0 0.065 13.5 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 RLN73120.1 - 0.048 13.1 0.0 0.63 9.5 0.0 2.4 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 RLN73120.1 - 0.073 12.2 0.2 0.23 10.5 0.1 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain 3HCDH_N PF02737.18 RLN73120.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain tRNA_m1G_MT PF01746.21 RLN73121.1 - 6.3e-14 52.1 0.0 9.8e-12 45.0 0.0 2.7 1 1 1 2 2 2 2 tRNA (Guanine-1)-methyltransferase DNA_pol3_a_NI PF14480.6 RLN73121.1 - 0.098 12.7 0.1 0.43 10.6 0.1 2.0 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus I DUF3934 PF13070.6 RLN73121.1 - 0.1 13.1 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3934) OmpH PF03938.14 RLN73122.1 - 0.13 12.6 1.7 0.3 11.4 1.7 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4472 PF14739.6 RLN73122.1 - 0.22 12.2 1.9 0.56 11.0 1.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) DUF4164 PF13747.6 RLN73122.1 - 0.8 10.0 3.8 0.39 11.0 1.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) 2OG-FeII_Oxy_2 PF13532.6 RLN73123.1 - 2.3e-20 73.6 0.0 4.7e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 RLN73123.1 - 5.7e-13 49.3 0.3 1.2e-12 48.3 0.3 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN73123.1 - 1.2e-10 41.9 0.4 2.7e-10 40.8 0.4 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 RLN73123.1 - 1.7e-05 24.8 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_12 PF08242.12 RLN73123.1 - 0.0011 19.7 0.1 0.0024 18.6 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN73123.1 - 0.0012 18.7 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 RLN73123.1 - 0.0096 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 RLN73123.1 - 0.045 13.4 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.6 RLN73123.1 - 0.064 13.1 0.0 0.18 11.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Ank_5 PF13857.6 RLN73124.1 - 4.3e-08 33.3 0.0 2.7e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) FYVE PF01363.21 RLN73124.1 - 1.6e-06 28.1 4.3 3.1e-06 27.2 4.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger Ank_2 PF12796.7 RLN73124.1 - 4.8e-05 23.9 0.0 9.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN73124.1 - 0.00019 21.9 0.0 0.0004 20.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 RLN73124.1 - 0.055 14.0 0.3 0.68 10.5 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 RLN73124.1 - 0.11 13.1 0.0 1.7 9.4 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat Cadherin_2 PF08266.12 RLN73124.1 - 0.17 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Cadherin-like DUF3835 PF12927.7 RLN73124.1 - 0.73 10.7 4.4 0.99 10.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) FYVE_2 PF02318.16 RLN73124.1 - 1.4 9.1 4.1 4.2 7.6 4.1 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger Crust_neurohorm PF01147.17 RLN73124.1 - 2.8 7.8 10.0 0.11 12.3 0.4 2.4 1 1 1 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family LEAP-2 PF07359.11 RLN73125.1 - 0.026 14.3 0.1 0.34 10.8 0.1 2.4 2 0 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Nucleoside_tran PF01733.18 RLN73126.1 - 1.2e-53 182.6 8.3 1.2e-53 182.6 8.3 1.9 2 0 0 2 2 2 1 Nucleoside transporter FAM176 PF14851.6 RLN73126.1 - 0.67 9.6 3.0 0.42 10.3 0.1 2.0 2 0 0 2 2 2 0 FAM176 family ATP-synt_C PF00137.21 RLN73127.1 - 1.5e-18 66.9 8.7 1.6e-18 66.7 8.7 1.0 1 0 0 1 1 1 1 ATP synthase subunit C ATP-synt_C PF00137.21 RLN73128.1 - 1.7e-31 108.3 25.1 7.8e-24 83.8 14.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C FAD_binding_1 PF00667.20 RLN73129.1 - 3.6e-28 98.7 0.0 7.2e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 RLN73129.1 - 4.4e-20 72.3 0.0 9.1e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 RLN73129.1 - 1.6e-07 32.0 0.0 3.4e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain EF1_GNE PF00736.19 RLN73130.1 - 2.7e-31 107.6 1.1 5.3e-31 106.7 1.1 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain Pox_Ag35 PF03286.14 RLN73130.1 - 0.003 17.4 7.1 0.0042 16.9 7.1 1.2 1 0 0 1 1 1 1 Pox virus Ag35 surface protein CDC27 PF09507.10 RLN73130.1 - 0.0078 15.6 9.4 0.0089 15.5 9.4 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF2052 PF09747.9 RLN73130.1 - 0.028 14.5 5.8 0.038 14.1 5.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF3381 PF11861.8 RLN73130.1 - 0.04 13.7 6.3 0.063 13.1 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Stm1_N PF09598.10 RLN73130.1 - 0.092 13.6 10.6 0.086 13.7 3.8 2.4 2 0 0 2 2 2 0 Stm1 VIR_N PF15912.5 RLN73130.1 - 0.12 11.9 2.4 0.16 11.5 2.4 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal FAM176 PF14851.6 RLN73130.1 - 0.2 11.3 3.7 0.32 10.7 3.7 1.3 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 RLN73130.1 - 0.26 11.7 7.3 0.52 10.7 7.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 RLN73130.1 - 0.71 8.1 7.6 1 7.5 7.6 1.2 1 0 0 1 1 1 0 CDC45-like protein IFT57 PF10498.9 RLN73130.1 - 0.95 8.4 7.2 1.3 7.9 7.2 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CENP-B_dimeris PF09026.10 RLN73130.1 - 1.7 9.1 10.1 3.3 8.1 10.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TRAP_alpha PF03896.16 RLN73130.1 - 1.7 7.8 5.1 2.3 7.3 5.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 RLN73130.1 - 3.2 5.8 9.7 3.9 5.5 9.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi PAC1 PF16094.5 RLN73130.1 - 3.6 6.7 6.5 6.3 5.9 6.5 1.3 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 eIF3_subunit PF08597.10 RLN73130.1 - 8.3 6.2 24.1 13 5.6 24.1 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit FBPase PF00316.20 RLN73131.1 - 8.4e-101 335.2 2.3 1.2e-62 210.7 0.1 3.1 2 1 1 3 3 3 3 Fructose-1-6-bisphosphatase, N-terminal domain DUF1653 PF07866.11 RLN73131.1 - 0.00024 21.3 0.0 1.1 9.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1653) OCRE PF17780.1 RLN73131.1 - 0.039 14.0 0.0 16 5.6 0.0 2.6 2 0 0 2 2 2 0 OCRE domain Bud13 PF09736.9 RLN73132.1 - 9.2e-42 142.9 8.3 9.2e-42 142.9 8.3 3.6 3 2 1 4 4 4 1 Pre-mRNA-splicing factor of RES complex SNF5 PF04855.12 RLN73133.1 - 3.8e-20 72.7 1.4 7.6e-10 39.0 0.1 2.9 1 1 2 3 3 3 3 SNF5 / SMARCB1 / INI1 DUF3181 PF11378.8 RLN73133.1 - 0.092 13.1 0.0 6.9 7.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3181) SMK-1 PF04802.15 RLN73134.1 - 7.3e-21 74.9 0.0 1.6e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 DUF4820 PF16091.5 RLN73134.1 - 4.3 6.6 9.8 1.1 8.6 3.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4820) HTH_23 PF13384.6 RLN73135.1 - 7.8e-08 31.9 0.0 1.7e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 RLN73135.1 - 1.4e-07 31.1 0.1 4e-07 29.7 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 RLN73135.1 - 2.3e-07 30.6 0.0 4.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Tc3 transposase TatD_DNase PF01026.21 RLN73136.1 - 1.2e-28 100.2 0.1 4.4e-25 88.5 0.0 2.0 1 1 1 2 2 2 2 TatD related DNase Med22 PF06179.12 RLN73137.1 - 5.7e-12 45.8 0.2 2.8e-11 43.6 0.2 1.8 1 1 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Apolipoprotein PF01442.18 RLN73137.1 - 0.042 13.7 0.0 0.38 10.6 0.1 2.0 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain HSBP1 PF06825.12 RLN73137.1 - 0.1 12.5 0.5 0.25 11.2 0.1 1.9 2 0 0 2 2 2 0 Heat shock factor binding protein 1 SNARE PF05739.19 RLN73137.1 - 0.17 11.9 0.4 46 4.1 0.0 3.2 3 0 0 3 3 3 0 SNARE domain HMG_box PF00505.19 RLN73138.1 - 4.3e-09 36.7 0.0 7.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box MATalpha_HMGbox PF04769.12 RLN73138.1 - 0.0032 16.8 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box HMG_box_2 PF09011.10 RLN73138.1 - 0.004 17.7 0.0 0.0092 16.6 0.0 1.6 1 0 0 1 1 1 1 HMG-box domain WD40 PF00400.32 RLN73139.1 - 1e-12 48.3 15.4 9.9e-05 23.0 0.1 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ PF01011.21 RLN73139.1 - 0.015 15.2 0.0 0.042 13.8 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat PQQ_3 PF13570.6 RLN73139.1 - 0.044 14.3 0.3 0.41 11.2 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain Cytochrom_D1 PF02239.16 RLN73139.1 - 0.048 12.2 0.6 0.1 11.1 0.1 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF1547 PF07577.11 RLN73139.1 - 0.13 12.7 0.1 0.47 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) MBOAT PF03062.19 RLN73146.1 - 8.3e-31 107.6 17.0 6.7e-30 104.6 17.0 2.0 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 RLN73146.1 - 0.00011 22.4 1.7 0.00011 22.4 1.7 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DUF1336 PF07059.12 RLN73147.1 - 3.4e-54 184.3 0.0 4e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) WD40 PF00400.32 RLN73148.1 - 1.5e-20 73.1 24.6 0.0027 18.5 0.1 10.1 9 1 0 9 9 9 5 WD domain, G-beta repeat MMR_HSR1 PF01926.23 RLN73148.1 - 5.3e-19 68.4 0.0 1e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN73148.1 - 8.2e-08 31.9 0.1 1.3e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B ANAPC4_WD40 PF12894.7 RLN73148.1 - 2.7e-06 27.6 0.0 0.088 13.1 0.0 4.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain MnmE_helical PF12631.7 RLN73148.1 - 4.9e-05 23.6 0.0 7.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 MnmE helical domain Dynamin_N PF00350.23 RLN73148.1 - 0.0013 18.9 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 RLN73148.1 - 0.0072 16.2 0.1 0.5 10.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 RLN73148.1 - 0.0093 16.5 0.0 0.016 15.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Choline_sulf_C PF12411.8 RLN73148.1 - 0.078 12.8 0.0 0.28 11.0 0.0 1.9 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal cobW PF02492.19 RLN73148.1 - 0.13 11.8 0.4 2.2 7.8 0.2 2.4 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1_Xtn PF16897.5 RLN73148.1 - 0.18 11.8 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain His_Phos_1 PF00300.22 RLN73149.1 - 0.00046 19.9 0.0 0.00073 19.3 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Spore_YhcN_YlaJ PF09580.10 RLN73149.1 - 0.23 11.6 0.0 0.28 11.3 0.0 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Ras PF00071.22 RLN73150.1 - 1.7e-06 27.7 0.1 0.00022 20.9 0.0 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 RLN73150.1 - 0.0072 16.5 0.2 0.92 9.7 0.0 3.1 2 1 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase GREB1 PF15782.5 RLN73150.1 - 0.19 8.8 8.1 0.25 8.4 8.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 RLN73150.1 - 4.1 7.3 14.8 6.9 6.6 14.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MnmE_helical PF12631.7 RLN73151.1 - 1.8e-18 67.5 0.4 2.4e-18 67.0 0.4 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 RLN73151.1 - 4e-08 33.6 0.4 3.1e-06 27.5 0.4 2.2 1 1 0 1 1 1 1 GTP-binding protein TrmE N-terminus Pkinase PF00069.25 RLN73152.1 - 9.2e-69 231.7 0.0 4.7e-68 229.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN73152.1 - 1e-28 100.3 0.0 6.9e-28 97.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 RLN73152.1 - 6.1e-26 88.0 5.3 3.2e-08 32.6 0.4 4.9 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RLN73152.1 - 1.5e-24 86.2 0.6 1.7e-11 44.4 0.0 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN73152.1 - 9.5e-22 75.0 2.0 2.6e-05 23.8 0.0 5.2 5 1 0 5 5 4 4 EF-hand domain EF-hand_8 PF13833.6 RLN73152.1 - 1.5e-19 69.6 8.1 1.7e-09 37.4 0.6 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 RLN73152.1 - 6.4e-17 60.2 3.8 7.8e-05 22.0 0.4 4.6 4 0 0 4 4 4 4 EF hand Tcf25 PF04910.14 RLN73152.1 - 2e-08 33.7 0.0 3.8e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Kdo PF06293.14 RLN73152.1 - 3e-08 33.3 0.1 2.9e-07 30.0 0.2 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_9 PF14658.6 RLN73152.1 - 3.4e-07 30.5 0.2 0.006 16.9 0.0 3.1 2 1 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 RLN73152.1 - 0.00054 19.9 0.5 0.6 10.1 0.2 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RLN73152.1 - 0.0012 19.2 1.1 2.3 8.6 0.0 3.0 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.23 RLN73152.1 - 0.0018 18.3 0.1 0.0018 18.3 0.1 2.8 2 2 0 2 2 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 RLN73152.1 - 0.01 15.4 0.1 0.024 14.2 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Dockerin_1 PF00404.18 RLN73152.1 - 0.051 13.8 4.0 6.7 7.0 4.0 3.3 1 1 0 1 1 1 0 Dockerin type I domain NAM-associated PF14303.6 RLN73152.1 - 0.87 10.3 6.8 12 6.5 6.6 2.2 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain TFIIA PF03153.13 RLN73152.1 - 1.9 8.4 13.7 3.1 7.7 13.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 RLN73152.1 - 4.9 6.7 7.2 8.1 6.0 7.2 1.3 1 0 0 1 1 1 0 Spt20 family DUF1336 PF07059.12 RLN73153.1 - 2.8e-59 200.9 0.0 7.7e-59 199.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1336) Tcf25 PF04910.14 RLN73153.1 - 2.9e-43 148.3 0.2 4.9e-43 147.6 0.2 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TFIIF_alpha PF05793.12 RLN73153.1 - 0.3 9.7 25.3 0.47 9.0 25.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop53 PF07767.11 RLN73153.1 - 1.3 8.3 22.3 2.1 7.6 22.3 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RR_TM4-6 PF06459.12 RLN73153.1 - 1.9 8.2 14.8 3.7 7.3 14.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SIT PF15330.6 RLN73153.1 - 4.2 7.8 8.6 2.8 8.4 6.4 1.9 1 1 1 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT UvrA_inter PF17760.1 RLN73155.1 - 0.35 10.9 3.9 10 6.2 0.2 3.0 2 1 1 3 3 3 0 UvrA interaction domain zf-ZPR1 PF03367.13 RLN73156.1 - 1.4e-100 333.7 0.0 7.1e-50 169.0 0.0 3.1 2 1 0 2 2 2 2 ZPR1 zinc-finger domain tRNA_bind_3 PF17176.4 RLN73156.1 - 0.21 11.9 1.7 0.73 10.1 0.5 2.2 2 0 0 2 2 2 0 tRNA-binding domain TPR_12 PF13424.6 RLN73156.1 - 1.5 9.2 8.0 0.39 11.1 3.7 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat Kinesin PF00225.23 RLN73157.1 - 9.2e-55 185.9 0.0 5.5e-45 153.7 0.0 2.2 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 RLN73157.1 - 3.8e-21 75.6 0.0 1.5e-20 73.7 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding AAA_30 PF13604.6 RLN73157.1 - 0.086 12.5 0.2 0.28 10.9 0.2 1.8 1 0 0 1 1 1 0 AAA domain RNB PF00773.19 RLN73158.1 - 2.7e-85 286.6 0.0 4.8e-85 285.8 0.0 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 RLN73158.1 - 3.9e-15 55.6 0.0 1e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 RLN73158.1 - 4.7e-06 26.4 0.0 9.8e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 RLN73158.1 - 0.069 13.1 0.0 0.48 10.4 0.0 2.4 2 1 0 2 2 2 0 S1 domain Myosin_head PF00063.21 RLN73160.1 - 8.7e-213 708.3 0.0 1.8e-212 707.3 0.0 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_30 PF13604.6 RLN73160.1 - 0.00027 20.7 0.1 0.00077 19.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RLN73160.1 - 0.0075 16.5 0.0 0.03 14.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RLN73160.1 - 0.01 16.2 0.0 0.058 13.8 0.0 2.3 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 RLN73160.1 - 0.013 14.6 0.4 0.026 13.6 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 RLN73160.1 - 0.015 15.6 0.0 0.059 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 RLN73160.1 - 0.035 13.5 0.0 0.082 12.2 0.0 1.5 1 0 0 1 1 1 0 KaiC DUF1800 PF08811.11 RLN73161.1 - 0.062 12.3 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Amino_oxidase PF01593.24 RLN73162.1 - 0.00073 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase PH PF00169.29 RLN73162.1 - 0.0024 18.4 0.0 0.0058 17.1 0.0 1.7 1 0 0 1 1 1 1 PH domain Frankia_peptide PF14407.6 RLN73162.1 - 0.019 15.0 0.5 0.18 11.8 0.0 2.6 2 1 1 3 3 3 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. NAD_binding_8 PF13450.6 RLN73162.1 - 0.025 14.8 0.2 0.057 13.7 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 RLN73162.1 - 0.13 11.5 0.1 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain PH_8 PF15409.6 RLN73162.1 - 0.16 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain GAS PF13851.6 RLN73163.1 - 6.7e-27 94.1 5.0 1e-26 93.6 5.0 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Transcrip_act PF04949.13 RLN73163.1 - 0.0027 17.6 0.6 0.0037 17.2 0.6 1.2 1 0 0 1 1 1 1 Transcriptional activator Pilus_CpaD PF09476.10 RLN73163.1 - 0.051 13.3 0.1 0.21 11.3 0.0 1.8 1 1 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) IFT20 PF14931.6 RLN73163.1 - 0.069 13.3 2.4 9.2 6.5 0.8 2.3 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF2203 PF09969.9 RLN73163.1 - 0.12 13.1 1.9 3.5 8.4 0.4 2.2 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) CENP-F_leu_zip PF10473.9 RLN73163.1 - 0.22 11.5 4.3 1 9.4 1.7 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Dicty_CAR PF05462.11 RLN73164.1 - 0.001 18.2 14.8 0.0016 17.6 14.8 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor DUF1181 PF06680.11 RLN73164.1 - 0.022 14.6 0.1 0.065 13.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1181) Nop53 PF07767.11 RLN73164.1 - 0.085 12.2 2.4 0.15 11.4 2.4 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) WD40 PF00400.32 RLN73165.1 - 0.0001 23.0 6.0 0.0043 17.9 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 RLN73165.1 - 0.13 12.3 0.1 31 4.7 0.1 2.8 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Med26 PF08711.11 RLN73166.1 - 2.1e-13 50.1 0.1 1.9e-12 47.0 0.0 2.4 2 0 0 2 2 2 1 TFIIS helical bundle-like domain PTPS PF01242.19 RLN73166.1 - 0.14 12.2 0.1 5 7.1 0.0 2.3 1 1 1 2 2 2 0 6-pyruvoyl tetrahydropterin synthase GBR_NSP5 PF17580.2 RLN73167.1 - 1.2 8.9 6.9 3.3 7.5 0.5 2.9 2 0 0 2 2 2 0 Group B Rotavirus Non-structural protein 5 Fib_alpha PF08702.10 RLN73167.1 - 7.9 6.7 29.1 1.8 8.8 6.5 3.7 3 2 1 4 4 4 0 Fibrinogen alpha/beta chain family Pkinase_Tyr PF07714.17 RLN73169.1 - 1.5e-39 135.9 0.0 2.7e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN73169.1 - 1.9e-35 122.5 0.0 3e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.23 RLN73169.1 - 2.9e-35 119.2 17.8 4e-05 23.5 0.1 9.8 9 0 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN73169.1 - 1.5e-12 46.7 2.4 14 6.2 0.0 8.6 8 0 0 8 8 8 0 HEAT repeat HEAT_EZ PF13513.6 RLN73169.1 - 1.1e-09 38.6 13.2 0.046 14.2 0.1 6.3 4 2 2 6 6 6 4 HEAT-like repeat Acyl-CoA_dh_N PF02771.16 RLN73169.1 - 2.2e-06 28.3 3.4 43 4.8 0.0 7.3 4 2 4 8 8 8 0 Acyl-CoA dehydrogenase, N-terminal domain Atx10homo_assoc PF09759.9 RLN73169.1 - 2.3e-06 27.5 1.4 0.31 11.1 0.1 5.2 1 1 5 7 7 7 2 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 RLN73169.1 - 0.00027 21.3 29.2 0.069 13.5 3.1 6.0 2 1 4 6 6 6 5 HEAT repeats HEAT_PBS PF03130.16 RLN73169.1 - 0.0029 18.1 33.1 5.8 7.9 0.0 9.8 10 0 0 10 10 9 1 PBS lyase HEAT-like repeat DUF4439 PF14530.6 RLN73169.1 - 0.0049 17.6 18.6 0.17 12.6 0.8 5.0 3 1 2 5 5 5 3 Domain of unknown function (DUF4439) Kinase-like PF14531.6 RLN73169.1 - 0.019 14.3 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Arylsulfotran_N PF17425.2 RLN73169.1 - 0.034 14.2 0.0 1.1e+02 3.0 0.0 5.0 6 0 0 6 6 6 0 Arylsulfotransferase Ig-like domain HEM4 PF02602.15 RLN73169.1 - 0.11 11.9 1.2 37 3.6 0.0 4.0 2 1 1 4 4 4 0 Uroporphyrinogen-III synthase HemD Arm_2 PF04826.13 RLN73169.1 - 0.14 11.6 0.0 6 6.3 0.0 2.8 1 1 1 2 2 2 0 Armadillo-like Myb_DNA-binding PF00249.31 RLN73171.1 - 1.1e-09 38.4 0.1 2.1e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN73171.1 - 0.0056 16.9 0.1 0.013 15.8 0.1 1.6 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 RLN73172.1 - 1.3e-09 38.1 0.0 2.1e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pho88 PF10032.9 RLN73173.1 - 5.9e-30 103.9 0.4 1.3e-29 102.8 0.4 1.5 1 0 0 1 1 1 1 Phosphate transport (Pho88) Ank_2 PF12796.7 RLN73173.1 - 9.8e-13 48.5 0.0 1.4e-06 28.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN73173.1 - 2.4e-06 28.0 0.0 8.6e-05 23.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN73173.1 - 0.00072 19.8 0.2 0.011 16.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN73173.1 - 0.001 19.4 0.0 0.48 11.0 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 RLN73173.1 - 0.002 18.5 0.0 0.42 11.3 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Glycoprotein PF03409.15 RLN73173.1 - 0.17 10.7 3.8 0.3 9.9 3.8 1.2 1 0 0 1 1 1 0 Transmembrane glycoprotein DUF3439 PF11921.8 RLN73173.1 - 1.8 8.6 7.7 4 7.4 7.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) MIP-T3_C PF17749.1 RLN73175.1 - 0.0048 16.9 0.1 0.0092 15.9 0.1 1.4 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 C-terminal region Pkinase PF00069.25 RLN73176.1 - 8.2e-34 117.2 0.0 1.2e-32 113.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN73176.1 - 3.9e-24 85.3 0.1 2.8e-15 56.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 RLN73176.1 - 0.0051 16.2 0.0 0.0096 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2894 PF11445.8 RLN73177.1 - 0.017 15.6 2.2 0.026 15.0 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Glyoxalase PF00903.25 RLN73178.1 - 3.5e-08 33.7 0.1 3.1e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 RLN73178.1 - 1.1e-05 25.6 0.0 0.013 15.8 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 RLN73178.1 - 0.0013 19.0 0.2 0.019 15.1 0.0 2.8 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 RLN73178.1 - 0.015 15.4 0.1 0.61 10.2 0.0 2.8 2 1 0 2 2 2 0 Glyoxalase-like domain HisKA PF00512.25 RLN73179.1 - 0.21 11.7 3.1 2.8 8.0 0.0 3.0 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain COMPASS-Shg1 PF05205.12 RLN73179.1 - 0.4 11.4 5.3 4.8 7.9 1.0 2.9 2 1 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 YtxH PF12732.7 RLN73179.1 - 1.7 9.2 4.2 8.7 7.0 0.1 2.8 2 0 0 2 2 2 0 YtxH-like protein VPS13 PF16908.5 RLN73180.1 - 5.3e-46 157.3 1.4 9.6e-22 77.9 0.0 3.8 4 0 0 4 4 4 3 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 RLN73180.1 - 8e-43 146.3 3.8 1.5e-40 138.8 0.3 2.9 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 RLN73180.1 - 6.9e-23 81.0 0.0 2.4e-22 79.2 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 RLN73180.1 - 1.2e-21 77.2 2.4 3.4e-20 72.5 0.0 4.0 5 0 0 5 5 5 1 Repeating coiled region of VPS13 SHR-BD PF06650.12 RLN73180.1 - 2e-21 76.6 0.1 1.6e-19 70.3 0.0 3.4 4 0 0 4 4 4 1 SHR-binding domain of vacuolar-sorting associated protein 13 PX PF00787.24 RLN73180.1 - 1.6e-11 44.2 0.0 3.7e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 PX domain ATG_C PF09333.11 RLN73180.1 - 0.0032 17.8 0.0 0.012 15.9 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Fmp27 PF10344.9 RLN73180.1 - 0.039 12.1 0.0 0.075 11.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 EF-hand_8 PF13833.6 RLN73184.1 - 0.021 14.7 0.1 0.2 11.5 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain pair EFG_C PF00679.24 RLN73184.1 - 0.027 14.5 0.0 0.42 10.7 0.0 2.7 2 1 1 3 3 3 0 Elongation factor G C-terminus EF-hand_1 PF00036.32 RLN73184.1 - 0.034 13.7 0.0 0.66 9.7 0.0 2.5 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 RLN73184.1 - 0.16 11.5 0.6 0.47 10.0 0.0 2.1 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 RLN73184.1 - 0.21 11.6 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain DUF5349 PF17298.2 RLN73185.1 - 0.27 11.0 7.8 0.33 10.7 7.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Citrate_synt PF00285.21 RLN73185.1 - 1.3 8.1 4.6 0.6 9.1 2.4 1.4 2 0 0 2 2 2 0 Citrate synthase, C-terminal domain HHH_8 PF14716.6 RLN73186.1 - 4.7e-09 36.5 2.4 1.1e-08 35.4 0.0 2.8 3 0 0 3 3 3 1 Helix-hairpin-helix domain ALS2CR8 PF15299.6 RLN73186.1 - 0.024 14.6 0.5 0.024 14.6 0.5 1.9 2 1 0 2 2 2 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 PhetRS_B1 PF18262.1 RLN73186.1 - 0.069 13.4 0.0 0.29 11.4 0.0 2.1 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain PDZ PF00595.24 RLN73187.1 - 2.4e-10 40.6 0.2 0.00047 20.5 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 RLN73187.1 - 1.8e-09 37.3 0.0 5.1e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PH PF00169.29 RLN73187.1 - 0.00012 22.5 0.2 0.00024 21.6 0.2 1.5 1 0 0 1 1 1 1 PH domain zf-RanBP PF00641.18 RLN73187.1 - 0.001 18.3 1.4 0.0021 17.3 1.4 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others PDZ_2 PF13180.6 RLN73187.1 - 0.0017 18.7 0.5 1.5 9.2 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PH_11 PF15413.6 RLN73187.1 - 0.04 14.3 1.9 0.094 13.2 0.5 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Nic96 PF04097.14 RLN73188.1 - 1.1e-122 410.6 0.0 1.4e-122 410.2 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 EMC3_TMCO1 PF01956.16 RLN73190.1 - 0.071 12.8 2.3 0.43 10.3 0.6 2.4 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like zf-C2H2 PF00096.26 RLN73195.1 - 2.7e-14 52.7 22.3 0.00086 19.6 0.2 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN73195.1 - 3e-12 46.3 16.3 0.016 16.0 0.2 5.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf_UBZ PF18439.1 RLN73195.1 - 2.8e-06 26.8 6.1 1.4 8.6 0.0 4.9 4 0 0 4 4 4 3 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 RLN73195.1 - 7.6e-06 25.8 10.4 0.097 12.7 0.0 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RLN73195.1 - 0.00047 20.4 6.1 0.14 12.4 0.6 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RLN73195.1 - 0.019 15.3 14.5 0.33 11.4 1.4 4.7 5 0 0 5 5 4 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RLN73195.1 - 0.02 15.2 14.2 9.2 6.7 0.8 4.9 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 RLN73195.1 - 0.1 12.5 11.3 8.5 6.4 0.4 4.1 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-LYAR PF08790.11 RLN73195.1 - 0.14 12.1 17.2 8.8 6.3 0.2 5.4 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger zf-C2H2_9 PF16293.5 RLN73195.1 - 0.32 10.9 5.9 6.1 6.8 0.0 3.7 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) DUF2256 PF10013.9 RLN73195.1 - 0.4 10.8 15.5 7.1 6.8 0.8 4.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-BED PF02892.15 RLN73195.1 - 0.62 10.1 8.3 3 7.9 0.1 3.8 4 0 0 4 4 4 0 BED zinc finger Zn-ribbon_8 PF09723.10 RLN73195.1 - 0.7 10.1 13.8 1.4 9.1 2.3 4.9 3 2 1 4 4 4 0 Zinc ribbon domain ADK_lid PF05191.14 RLN73195.1 - 0.71 9.9 9.1 0.052 13.5 1.3 2.9 2 1 0 2 2 2 0 Adenylate kinase, active site lid zinc_ribbon_9 PF14369.6 RLN73195.1 - 0.73 10.1 4.7 7.8 6.9 0.3 4.1 4 0 0 4 4 4 0 zinc-ribbon zf-ribbon_3 PF13248.6 RLN73195.1 - 1.7 8.1 12.9 5.7 6.5 0.3 4.1 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.7 RLN73195.1 - 2.9 8.0 22.7 0.21 11.6 4.1 3.3 1 1 1 2 2 2 0 Double zinc ribbon YhfH PF14149.6 RLN73195.1 - 4.7 7.3 12.9 2.3 8.3 0.2 3.8 4 0 0 4 4 4 0 YhfH-like protein CpXC PF14353.6 RLN73195.1 - 5 7.2 16.9 2.8 8.0 1.8 4.3 1 1 2 3 3 3 0 CpXC protein XPA_N PF01286.18 RLN73195.1 - 6.7 6.8 16.4 18 5.5 0.2 4.7 5 0 0 5 5 5 0 XPA protein N-terminal zf-C2H2_3 PF13878.6 RLN73195.1 - 8.9 6.2 9.0 12 5.9 0.0 4.1 4 0 0 4 4 4 0 zinc-finger of acetyl-transferase ESCO zf-C2H2_11 PF16622.5 RLN73195.1 - 9.4 6.1 17.2 10 5.9 0.1 4.5 4 0 0 4 4 4 0 zinc-finger C2H2-type efThoc1 PF11957.8 RLN73197.1 - 1.3e-106 357.2 0.0 2.2e-106 356.5 0.0 1.3 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Vault PF01505.18 RLN73197.1 - 1.6e-36 124.2 3.9 2.8e-10 40.2 0.0 4.6 4 0 0 4 4 4 4 Major Vault Protein repeat domain Vault_2 PF17794.1 RLN73197.1 - 1.7e-29 102.0 0.3 6.5e-16 58.5 0.1 3.0 3 0 0 3 3 3 2 Major Vault Protein repeat domain Ank_2 PF12796.7 RLN73197.1 - 7.1e-09 36.1 0.0 1.7e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN73197.1 - 2.6e-06 27.8 0.1 7.6e-06 26.4 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN73197.1 - 1.4e-05 25.1 0.0 0.36 11.5 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 RLN73197.1 - 0.00047 20.5 0.3 1.5 9.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RLN73197.1 - 0.0066 16.7 0.2 0.15 12.4 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Vault_3 PF17795.1 RLN73197.1 - 0.17 12.0 0.1 0.48 10.5 0.1 1.8 1 0 0 1 1 1 0 Major Vault Protein Repeat domain Vault_3 PF17795.1 RLN73198.1 - 3.7e-36 123.0 0.1 1.1e-33 115.1 0.1 2.3 2 0 0 2 2 2 2 Major Vault Protein Repeat domain Vault_4 PF17796.1 RLN73198.1 - 3e-26 91.3 0.0 3.2e-23 81.6 0.0 2.2 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault PF01505.18 RLN73198.1 - 0.039 14.1 4.5 0.18 12.0 1.0 2.7 2 1 0 2 2 2 0 Major Vault Protein repeat domain MFS_1 PF07690.16 RLN73199.1 - 4.3e-21 75.2 36.1 4.3e-21 75.2 36.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN73199.1 - 1.1e-10 41.0 9.3 1.1e-10 41.0 9.3 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter Ank_2 PF12796.7 RLN73201.1 - 2.9e-85 281.0 20.6 1.3e-15 57.7 1.4 7.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN73201.1 - 2.1e-72 238.6 11.5 1.3e-08 35.2 0.1 9.5 4 2 6 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN73201.1 - 8e-63 207.7 46.2 2.7e-08 33.9 0.1 12.5 1 1 12 13 13 13 13 Ankyrin repeats (many copies) Ank PF00023.30 RLN73201.1 - 7.1e-53 174.9 23.6 8.3e-05 22.9 0.0 13.6 13 0 0 13 13 13 10 Ankyrin repeat Ank_3 PF13606.6 RLN73201.1 - 6.8e-52 167.4 12.8 0.03 14.9 0.0 15.0 15 0 0 15 15 15 13 Ankyrin repeat Pkinase_Tyr PF07714.17 RLN73201.1 - 6e-09 35.6 0.0 1.8e-08 34.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RLN73201.1 - 1.6e-06 27.7 0.0 2.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SIP PF04954.13 RLN73201.1 - 3.3e-05 24.4 0.4 4.2 7.9 0.0 4.5 3 1 1 4 4 4 2 Siderophore-interacting protein PK_C PF02887.16 RLN73201.1 - 0.21 11.8 5.0 53 4.1 0.1 4.9 5 1 0 5 5 5 0 Pyruvate kinase, alpha/beta domain ArsP_1 PF03773.13 RLN73201.1 - 0.52 9.4 8.5 29 3.7 0.1 4.9 4 1 1 5 5 5 0 Predicted permease Glyco_hydro81C PF17652.1 RLN73215.1 - 3.9e-76 256.6 0.5 5.9e-76 256.0 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 RLN73215.1 - 1.9e-57 194.9 0.0 2.7e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Rer1 PF03248.13 RLN73216.1 - 4.1e-63 212.2 5.3 6.9e-63 211.4 5.3 1.3 1 0 0 1 1 1 1 Rer1 family CDP-OH_P_transf PF01066.21 RLN73217.1 - 1.6e-15 57.6 0.1 1.6e-15 57.6 0.1 1.9 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PAN_1 PF00024.26 RLN73218.1 - 8.5e-22 76.9 11.1 3.8e-09 36.4 0.6 3.5 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.6 RLN73218.1 - 3.5e-20 71.6 15.5 1.6e-08 34.3 0.8 4.5 5 0 0 5 5 5 3 PAN domain MANEC PF07502.14 RLN73218.1 - 0.48 10.7 14.5 1.7 9.0 0.2 4.2 4 0 0 4 4 4 0 MANEC domain Pico_P2A PF00947.19 RLN73218.1 - 6.5 6.8 15.3 6.5 6.8 2.9 2.2 2 0 0 2 2 2 0 Picornavirus core protein 2A Pur_ac_phosph_N PF16656.5 RLN73219.1 - 3.3e-19 69.3 9.5 3.3e-19 69.3 9.5 2.2 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 RLN73219.1 - 5.5e-19 69.5 1.7 8.4e-19 68.9 1.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 RLN73219.1 - 3.8e-16 59.7 0.1 1.5e-15 57.8 0.1 2.1 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 RLN73219.1 - 0.0033 17.6 0.1 0.1 12.7 0.0 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD_N PF16655.5 RLN73219.1 - 0.0059 17.1 0.9 0.014 15.9 0.9 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain FAD-oxidase_C PF02913.19 RLN73219.1 - 0.086 12.5 0.0 0.57 9.8 0.0 2.0 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain Cyclophil_like PF04126.13 RLN73222.1 - 0.028 14.2 0.2 1.2 9.0 0.1 2.5 1 1 1 2 2 2 0 Cyclophilin-like SRP14 PF02290.15 RLN73226.1 - 7.1e-12 45.5 0.1 1e-11 45.0 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein SAM_decarbox PF01536.16 RLN73226.1 - 0.065 12.2 0.0 0.068 12.2 0.0 1.0 1 0 0 1 1 1 0 Adenosylmethionine decarboxylase FA_desaturase_2 PF03405.14 RLN73226.1 - 0.1 11.4 0.1 0.11 11.3 0.1 1.0 1 0 0 1 1 1 0 Fatty acid desaturase AAA PF00004.29 RLN73227.1 - 4.1e-06 27.2 0.5 0.00016 22.1 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN73227.1 - 0.021 15.1 0.0 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RLN73227.1 - 0.056 13.8 3.1 0.57 10.5 3.1 2.9 1 1 0 1 1 1 0 AAA ATPase domain TIR-like PF10137.9 RLN73227.1 - 0.17 11.9 0.0 0.57 10.2 0.0 1.9 2 0 0 2 2 2 0 Predicted nucleotide-binding protein containing TIR-like domain Pkinase_Tyr PF07714.17 RLN73234.1 - 2.7e-38 131.7 0.0 4.4e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN73234.1 - 2.8e-37 128.5 0.0 1.2e-36 126.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.22 RLN73234.1 - 0.032 13.8 0.0 0.08 12.5 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 RLN73234.1 - 0.062 12.1 0.0 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Retrotrans_gag PF03732.17 RLN73242.1 - 2.8e-05 24.3 0.1 5.9e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein Aldo_ket_red PF00248.21 RLN73248.1 - 1.7e-72 244.1 0.0 1.9e-72 244.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ASH PF15780.5 RLN73253.1 - 5.5e-06 26.5 0.8 0.00089 19.4 0.0 3.5 2 1 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin WD40 PF00400.32 RLN73255.1 - 5.5e-30 103.0 11.9 2e-07 31.6 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 RLN73255.1 - 4.5e-29 100.5 1.2 1.6e-27 95.6 0.2 3.4 3 1 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.11 RLN73255.1 - 1.4e-06 28.3 0.7 0.0016 18.3 0.1 3.4 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 RLN73255.1 - 3e-05 24.2 0.6 0.034 14.5 0.0 3.7 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain HAD_2 PF13419.6 RLN73256.1 - 2.4e-05 24.5 0.0 2.4e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 RLN73256.1 - 0.012 16.0 0.0 0.013 15.9 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RLN73256.1 - 0.066 13.5 0.0 0.066 13.5 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PX PF00787.24 RLN73257.1 - 5e-12 45.8 0.0 5.8e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 PX domain PX PF00787.24 RLN73258.1 - 1.3e-07 31.6 0.0 1.4e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 PX domain FYVE PF01363.21 RLN73261.1 - 9e-13 48.2 10.2 1.7e-12 47.2 10.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger DUF326 PF03860.16 RLN73261.1 - 0.14 12.2 4.2 0.28 11.2 4.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF326) zf-RING_5 PF14634.6 RLN73261.1 - 0.25 11.3 4.8 0.59 10.1 2.5 2.1 2 0 0 2 2 2 0 zinc-RING finger domain C1_2 PF03107.16 RLN73261.1 - 2.7 8.4 7.3 5.1 7.5 4.2 2.3 2 0 0 2 2 2 0 C1 domain Prok-RING_2 PF14445.6 RLN73261.1 - 3.1 8.0 6.5 2.2 8.5 4.4 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 zf-CRD PF17979.1 RLN73261.1 - 5.3 7.1 11.6 85 3.2 0.0 2.6 2 1 0 2 2 2 0 Cysteine rich domain with multizinc binding regions FYVE PF01363.21 RLN73262.1 - 4.5e-10 39.5 15.6 4.5e-10 39.5 15.6 2.8 3 0 0 3 3 3 1 FYVE zinc finger FYVE PF01363.21 RLN73263.1 - 1.2e-12 47.8 14.1 4.1e-12 46.1 14.1 2.0 1 0 0 1 1 1 1 FYVE zinc finger zf-RING_2 PF13639.6 RLN73263.1 - 0.045 14.1 9.1 0.067 13.5 6.3 2.6 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 RLN73263.1 - 0.19 11.6 11.3 0.87 9.5 6.2 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN73263.1 - 0.38 10.8 6.3 0.4 10.7 3.1 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 RLN73263.1 - 2.4 8.1 9.1 23 5.0 0.1 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 RLN73264.1 - 6.2e-12 45.5 12.8 1.1e-11 44.7 12.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger ABATE PF07336.11 RLN73269.1 - 0.25 12.0 3.9 0.42 11.3 3.9 1.3 1 0 0 1 1 1 0 Putative stress-induced transcription regulator SR-25 PF10500.9 RLN73269.1 - 6.5 6.3 26.2 0.17 11.4 5.5 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 RLN73270.1 - 5e-53 180.2 0.0 8.7e-53 179.4 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN73270.1 - 9e-22 77.6 0.0 1.7e-21 76.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_7 PF13499.6 RLN73270.1 - 1.7e-13 50.8 1.5 1.4e-05 25.4 0.4 3.5 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN73270.1 - 5.4e-12 44.4 2.2 0.0015 18.0 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 RLN73270.1 - 5.3e-11 41.5 0.7 0.11 12.5 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 RLN73270.1 - 1.1e-09 37.3 3.9 0.008 15.6 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 RLN73270.1 - 2e-08 34.0 1.6 0.0069 16.2 0.4 4.1 4 0 0 4 4 4 2 EF-hand domain pair Kdo PF06293.14 RLN73270.1 - 0.028 13.8 0.1 0.065 12.6 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN73270.1 - 0.032 13.0 0.2 0.075 11.8 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase SPARC_Ca_bdg PF10591.9 RLN73270.1 - 0.043 14.1 0.7 5.3 7.4 0.1 2.7 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region GST_C_3 PF14497.6 RLN73272.1 - 8.3e-23 80.5 0.1 1.3e-22 79.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RLN73272.1 - 2.4e-08 34.2 0.0 5.7e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RLN73272.1 - 3.4e-06 27.2 0.1 5.7e-06 26.5 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RLN73272.1 - 1.5e-05 25.3 0.0 2.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN73272.1 - 0.00025 21.3 0.0 0.00043 20.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN73272.1 - 0.023 14.7 0.0 0.059 13.4 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 RLN73272.1 - 0.057 14.2 0.0 0.14 12.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 RLN73273.1 - 1.6e-17 63.5 0.4 2.3e-17 63.0 0.4 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RLN73273.1 - 2.6e-09 37.3 0.0 8.9e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RLN73273.1 - 1.1e-05 25.5 0.1 2.4e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RLN73273.1 - 0.0011 19.4 0.0 0.0041 17.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN73273.1 - 0.013 15.8 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain AATF-Che1 PF13339.6 RLN73274.1 - 0.15 12.8 1.0 6.2 7.5 0.1 2.3 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor SlyX PF04102.12 RLN73274.1 - 0.34 11.6 5.2 3.3 8.4 0.1 3.0 3 0 0 3 3 3 0 SlyX DUF4404 PF14357.6 RLN73274.1 - 1.7 9.3 4.9 1.9 9.2 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) ATG16 PF08614.11 RLN73275.1 - 1.4 9.1 30.4 0.79 9.9 9.3 3.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF5446 PF17522.2 RLN73275.1 - 5.4 7.3 12.9 0.43 10.8 0.8 4.0 2 1 3 5 5 5 0 Family of unknown function (DUF5446) YabA PF06156.13 RLN73275.1 - 5.7 7.6 21.0 0.26 11.9 3.8 3.3 2 2 1 3 3 3 0 Initiation control protein YabA Seryl_tRNA_N PF02403.22 RLN73275.1 - 9 6.6 17.6 0.78 10.0 2.7 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Utp14 PF04615.13 RLN73277.1 - 8.2 4.9 13.5 9.3 4.7 13.5 1.1 1 0 0 1 1 1 0 Utp14 protein ABC_tran PF00005.27 RLN73279.1 - 2.4e-06 28.1 0.2 4.1e-06 27.3 0.1 1.5 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 RLN73279.1 - 0.00048 20.5 0.3 0.00078 19.9 0.2 1.4 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 RLN73279.1 - 0.0012 18.2 0.2 0.0025 17.1 0.1 1.6 1 1 1 2 2 2 1 Zeta toxin RsgA_GTPase PF03193.16 RLN73279.1 - 0.0016 18.4 0.1 0.0019 18.2 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN73279.1 - 0.0017 18.0 0.1 0.0024 17.6 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN73279.1 - 0.005 17.1 0.1 0.0096 16.2 0.1 1.5 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 RLN73279.1 - 0.014 15.5 0.3 0.034 14.2 0.1 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF815 PF05673.13 RLN73279.1 - 0.017 14.3 0.0 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 RLN73279.1 - 0.024 14.6 0.1 0.045 13.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 RLN73279.1 - 0.033 13.9 0.2 0.15 11.8 0.0 1.9 1 1 1 2 2 2 0 AAA domain T2SSE PF00437.20 RLN73279.1 - 0.033 13.2 0.1 0.042 12.9 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 RLN73279.1 - 0.033 13.8 0.3 0.046 13.3 0.2 1.4 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 RLN73279.1 - 0.081 12.0 0.1 0.1 11.7 0.1 1.3 1 1 0 1 1 1 0 MCM P-loop domain AAA_18 PF13238.6 RLN73279.1 - 0.089 13.3 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 RLN73279.1 - 0.11 12.6 1.6 0.53 10.3 0.4 1.9 1 1 1 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 RLN73279.1 - 0.12 12.2 0.1 0.59 9.9 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 RLN73279.1 - 0.12 11.7 1.2 0.22 10.8 0.8 1.7 1 1 1 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.12 RLN73279.1 - 0.12 12.3 0.3 0.25 11.2 0.2 1.6 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 RLN73279.1 - 0.13 11.9 0.2 0.6 9.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 RLN73279.1 - 0.17 11.3 0.5 0.7 9.3 0.0 1.8 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RLN73279.1 - 0.2 11.4 0.0 0.24 11.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DEAD PF00270.29 RLN73283.1 - 7.7e-46 156.1 1.0 3.8e-45 153.8 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN73283.1 - 2.6e-24 85.7 0.0 1.1e-23 83.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 RLN73283.1 - 1.3e-17 63.8 0.1 5e-17 61.9 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 RLN73283.1 - 1.6e-06 28.2 0.6 3.1e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 RLN73283.1 - 0.053 13.2 0.1 0.053 13.2 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 RLN73283.1 - 0.24 11.7 1.2 1.2 9.4 1.2 2.2 1 1 0 1 1 1 0 AAA domain Spore_coat_CotO PF14153.6 RLN73283.1 - 4 7.3 12.1 8.3 6.3 12.1 1.5 1 0 0 1 1 1 0 Spore coat protein CotO Pox_Ag35 PF03286.14 RLN73283.1 - 4.6 7.0 13.2 8.9 6.0 13.2 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Kelch_6 PF13964.6 RLN73284.1 - 8.9e-27 92.5 5.5 1.7e-07 31.3 0.2 5.1 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.6 RLN73284.1 - 8.3e-25 86.5 0.4 1.7e-05 25.0 0.0 5.3 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_1 PF01344.25 RLN73284.1 - 3.7e-24 84.0 2.8 5.5e-08 32.3 0.0 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 RLN73284.1 - 8e-22 77.0 5.0 1.9e-05 24.6 0.0 5.0 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN73284.1 - 4.9e-20 71.1 2.0 4.9e-06 26.4 0.0 4.3 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 RLN73284.1 - 7e-20 70.2 1.9 8e-05 22.5 0.1 4.6 4 0 0 4 4 4 4 Kelch motif RAG2 PF03089.14 RLN73284.1 - 4.2e-05 22.7 0.2 0.0025 16.9 0.1 2.9 2 1 0 2 2 2 1 Recombination activating protein 2 Tim44 PF04280.15 RLN73285.1 - 6.3e-28 97.7 0.1 6.3e-28 97.7 0.1 2.4 2 1 1 3 3 3 1 Tim44-like domain Membralin PF09746.9 RLN73285.1 - 0.009 15.1 2.9 0.022 13.8 2.9 1.6 1 0 0 1 1 1 1 Tumour-associated protein Senescence PF06911.12 RLN73285.1 - 0.05 13.9 9.7 0.23 11.8 0.0 2.7 3 0 0 3 3 3 0 Senescence-associated protein Carbpep_Y_N PF05388.11 RLN73285.1 - 0.32 11.5 11.3 2.7 8.6 6.8 2.7 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide Cauli_AT PF03233.13 RLN73285.1 - 0.62 10.0 8.4 0.23 11.3 5.1 1.9 2 0 0 2 2 2 0 Aphid transmission protein Prominin PF05478.11 RLN73285.1 - 1.9 6.3 4.9 1.9 6.4 2.2 2.0 2 0 0 2 2 2 0 Prominin DivIVA PF05103.13 RLN73285.1 - 2.8 8.0 21.0 7.5 6.6 13.9 2.7 2 0 0 2 2 2 0 DivIVA protein GAS PF13851.6 RLN73285.1 - 3.9 6.8 19.8 0.96 8.8 14.3 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Exonuc_VII_L PF02601.15 RLN73285.1 - 7.3 6.1 14.1 2.2 7.8 5.8 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Ank_2 PF12796.7 RLN73286.1 - 9.3e-66 218.4 13.3 1.7e-16 60.6 0.2 6.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN73286.1 - 1.9e-55 184.6 11.3 1.7e-08 34.8 0.0 8.4 2 1 6 9 9 9 9 Ankyrin repeats (many copies) Pkinase PF00069.25 RLN73286.1 - 1.6e-52 178.5 0.0 3.1e-41 141.5 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN73286.1 - 2.8e-51 174.3 0.0 5.8e-41 140.5 0.0 3.3 2 1 0 2 2 2 2 Protein tyrosine kinase Ank_5 PF13857.6 RLN73286.1 - 6.1e-44 147.5 11.4 6.8e-08 32.6 0.2 10.3 1 1 10 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 RLN73286.1 - 2e-41 138.6 17.0 3.3e-05 24.1 0.0 11.6 12 0 0 12 12 12 8 Ankyrin repeat Ank_3 PF13606.6 RLN73286.1 - 4.3e-35 115.8 4.6 0.0072 16.8 0.0 11.8 12 0 0 12 12 12 8 Ankyrin repeat Pkinase_fungal PF17667.1 RLN73286.1 - 4e-05 22.6 0.0 0.0001 21.3 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 RLN73286.1 - 0.077 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family PK_C PF02887.16 RLN73286.1 - 0.082 13.1 3.1 13 6.0 0.1 4.2 4 0 0 4 4 4 0 Pyruvate kinase, alpha/beta domain APH PF01636.23 RLN73286.1 - 0.092 12.7 0.1 0.092 12.7 0.1 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family WGG PF10273.9 RLN73286.1 - 0.21 12.3 0.9 13 6.5 0.1 3.2 3 0 0 3 3 3 0 Pre-rRNA-processing protein TSR2 La PF05383.17 RLN73288.1 - 1.2e-11 44.4 0.1 3.4e-11 43.0 0.1 1.7 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 RLN73288.1 - 1.1e-09 38.0 0.1 1.9e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_2 PF07719.17 RLN73289.1 - 6.3e-07 29.0 0.1 3 8.2 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN73289.1 - 0.0002 21.0 1.5 0.018 14.8 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN73289.1 - 0.0006 20.0 3.1 0.28 11.5 0.0 3.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN73289.1 - 0.0026 18.2 12.7 0.4 11.2 0.0 5.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN73289.1 - 0.0061 17.3 2.2 5.6 8.1 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN73289.1 - 0.015 15.3 0.1 2.2 8.5 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_C23 PF05379.11 RLN73289.1 - 0.027 14.6 0.1 0.053 13.7 0.1 1.4 1 0 0 1 1 1 0 Carlavirus endopeptidase TPR_8 PF13181.6 RLN73289.1 - 0.031 14.5 0.1 97 3.6 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN73289.1 - 0.063 13.9 0.4 1.2e+02 3.7 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN73289.1 - 0.074 13.7 8.2 14 6.4 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1840 PF08895.11 RLN73289.1 - 0.077 13.3 0.0 15 6.0 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) Ank_2 PF12796.7 RLN73296.1 - 5.5e-37 126.2 5.4 6.4e-16 58.7 0.4 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN73296.1 - 3.9e-28 97.5 2.8 2.5e-08 34.3 0.0 4.7 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN73296.1 - 1e-22 79.9 5.8 4.2e-06 26.9 0.1 6.4 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN73296.1 - 3.6e-21 73.0 1.4 0.0094 16.4 0.0 6.8 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 RLN73296.1 - 4.3e-21 74.3 12.1 0.00039 20.7 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat Pkinase_Tyr PF07714.17 RLN73296.1 - 3.6e-17 62.5 0.0 1.2e-06 28.0 0.0 3.3 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN73296.1 - 2.7e-16 59.7 0.0 1.5e-08 34.3 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain DUF1949 PF09186.11 RLN73296.1 - 0.00071 19.4 0.1 14 5.7 0.0 3.7 3 0 0 3 3 3 2 Domain of unknown function (DUF1949) PK_C PF02887.16 RLN73296.1 - 0.094 13.0 1.1 68 3.7 0.0 3.5 3 0 0 3 3 3 0 Pyruvate kinase, alpha/beta domain UBA PF00627.31 RLN73296.1 - 2.6 8.0 4.2 74 3.4 0.1 3.3 3 0 0 3 3 3 0 UBA/TS-N domain Glu_cyclase_2 PF05096.12 RLN73298.1 - 1.7e-67 227.5 0.0 2.1e-67 227.2 0.0 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase GFP PF01353.22 RLN73298.1 - 0.028 13.9 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Green fluorescent protein NAD_binding_6 PF08030.12 RLN73299.1 - 6.6e-36 123.8 0.1 7.9e-36 123.5 0.1 1.1 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 RLN73299.1 - 0.0019 18.8 0.2 0.011 16.4 0.2 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF4038 PF13204.6 RLN73303.1 - 6.6e-19 68.7 0.5 8e-19 68.4 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Collagen_bind_2 PF12904.7 RLN73303.1 - 5e-11 42.4 0.0 8.7e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Putative collagen-binding domain of a collagenase zf-BED PF02892.15 RLN73304.1 - 0.014 15.4 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 BED zinc finger FUSC PF04632.12 RLN73304.1 - 0.056 12.0 0.7 0.12 10.9 0.7 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family PDE4_UCR PF18100.1 RLN73305.1 - 0.82 10.3 3.5 0.88 10.2 0.0 2.9 3 0 0 3 3 3 0 Phosphodiesterase 4 upstream conserved regions (UCR) Sec15 PF04091.12 RLN73307.1 - 4.5e-26 92.0 0.1 2.2e-25 89.7 0.0 2.0 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Vps51 PF08700.11 RLN73307.1 - 0.00059 19.9 0.1 0.0017 18.4 0.1 1.7 1 0 0 1 1 1 1 Vps51/Vps67 Pox_P21 PF05313.12 RLN73307.1 - 0.78 9.3 5.6 3 7.4 5.6 2.0 1 0 0 1 1 1 0 Poxvirus P21 membrane protein DDE_Tnp_IS240 PF13610.6 RLN73308.1 - 0.0096 16.2 0.1 0.025 14.8 0.0 1.7 2 1 1 3 3 3 1 DDE domain PX PF00787.24 RLN73308.1 - 0.034 14.1 0.1 0.079 13.0 0.1 1.6 1 1 0 1 1 1 0 PX domain Baculo_ODV-E27 PF05314.11 RLN73308.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Baculovirus occlusion-derived virus envelope protein EC27 zinc_ribbon_9 PF14369.6 RLN73310.1 - 0.078 13.3 0.7 0.32 11.3 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon DEAD PF00270.29 RLN73315.1 - 1.7e-15 57.2 0.0 2.3e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN73316.1 - 5.8e-22 78.1 0.0 8.5e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 RLN73316.1 - 0.06 12.5 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase ABC_tran PF00005.27 RLN73317.1 - 1.9e-38 132.1 0.7 1e-19 71.4 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 RLN73317.1 - 1.8e-24 85.6 8.1 1.5e-22 79.4 7.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 RLN73317.1 - 8.2e-16 58.7 3.5 0.00015 21.7 0.0 4.0 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RLN73317.1 - 1.2e-06 28.1 7.4 0.011 15.2 0.0 3.5 4 0 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 RLN73317.1 - 0.00022 21.5 0.3 0.049 13.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain DUF3584 PF12128.8 RLN73317.1 - 0.0023 15.5 0.1 0.0023 15.5 0.1 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3584) AAA_29 PF13555.6 RLN73317.1 - 0.0024 17.6 1.3 0.056 13.2 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 RLN73317.1 - 0.0043 17.1 0.0 0.19 11.8 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 RLN73317.1 - 0.0047 17.5 0.4 3.4 8.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain FmiP_Thoc5 PF09766.9 RLN73317.1 - 0.0058 16.0 6.2 0.035 13.4 1.0 2.1 2 0 0 2 2 2 1 Fms-interacting protein/Thoc5 AAA_22 PF13401.6 RLN73317.1 - 0.0066 16.7 0.7 0.031 14.5 0.0 2.5 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.6 RLN73317.1 - 0.013 15.8 0.4 1.8 8.8 0.1 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 RLN73317.1 - 0.022 15.1 0.1 0.47 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.15 RLN73317.1 - 0.038 13.9 0.1 0.095 12.6 0.1 1.7 1 0 0 1 1 1 0 NTPase RsgA_GTPase PF03193.16 RLN73317.1 - 0.042 13.8 0.4 0.85 9.5 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase NPV_P10 PF05531.12 RLN73317.1 - 0.048 14.1 1.5 0.16 12.4 1.5 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein AAA_15 PF13175.6 RLN73317.1 - 0.059 13.1 0.1 0.059 13.1 0.1 3.8 4 1 0 4 4 3 0 AAA ATPase domain AAA_25 PF13481.6 RLN73317.1 - 0.078 12.5 0.9 0.77 9.3 0.1 2.7 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 RLN73317.1 - 0.1 12.7 0.3 3.6 7.6 0.0 3.4 4 2 0 4 4 4 0 AAA domain NACHT PF05729.12 RLN73317.1 - 0.1 12.5 1.0 0.32 10.9 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 RLN73317.1 - 0.13 12.7 2.7 0.24 11.8 0.1 2.8 2 2 1 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 RLN73317.1 - 0.15 12.2 3.0 2.3 8.4 0.1 3.3 3 1 0 3 3 3 0 AAA domain AAA_23 PF13476.6 RLN73317.1 - 0.32 11.4 14.0 0.066 13.7 0.4 4.2 4 1 0 4 4 4 0 AAA domain AAA_30 PF13604.6 RLN73317.1 - 0.44 10.2 5.3 0.56 9.9 0.7 3.2 3 1 0 3 3 3 0 AAA domain RecG_N PF17190.4 RLN73317.1 - 0.48 11.2 7.3 2.9 8.7 0.2 3.1 2 1 1 3 3 3 0 RecG N-terminal helical domain AAA_13 PF13166.6 RLN73317.1 - 0.62 8.6 11.4 1.6 7.3 0.0 3.6 3 1 0 3 3 3 0 AAA domain DUF16 PF01519.16 RLN73317.1 - 1 9.9 8.5 1.6 9.2 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF4200 PF13863.6 RLN73317.1 - 1.3 9.5 11.7 0.34 11.3 4.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Dynamin_N PF00350.23 RLN73317.1 - 1.9 8.5 8.9 19 5.3 0.1 4.1 3 1 1 4 4 4 0 Dynamin family Histone_HNS PF00816.21 RLN73317.1 - 2.1 9.3 6.0 0.8 10.6 1.2 2.4 2 0 0 2 2 2 0 H-NS histone family DUF87 PF01935.17 RLN73317.1 - 2.1 8.4 9.8 3.1 7.8 0.0 4.0 4 0 0 4 4 4 0 Helicase HerA, central domain GrpE PF01025.19 RLN73317.1 - 3.1 7.4 14.2 0.1 12.3 2.7 2.9 3 0 0 3 3 3 0 GrpE Mesd PF10185.9 RLN73318.1 - 0.0018 18.2 0.3 0.0027 17.7 0.3 1.3 1 1 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor POX PF07526.11 RLN73318.1 - 0.26 11.8 2.8 0.36 11.4 2.8 1.3 1 0 0 1 1 1 0 Associated with HOX NARP1 PF12569.8 RLN73318.1 - 3.4 6.5 10.9 4 6.2 10.9 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Metallophos PF00149.28 RLN73319.1 - 5.6e-19 69.4 0.1 9.5e-19 68.7 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Thr_synth_N PF14821.6 RLN73320.1 - 1.2e-26 92.7 0.0 3e-26 91.4 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 RLN73320.1 - 3.9e-20 72.4 3.7 7.4e-19 68.2 0.1 3.0 1 1 1 2 2 2 1 Pyridoxal-phosphate dependent enzyme TIP120 PF08623.10 RLN73321.1 - 8.3e-48 162.3 1.4 1.1e-45 155.4 0.1 3.7 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 RLN73321.1 - 8.2e-16 56.8 11.2 0.027 14.7 0.0 11.0 12 0 0 12 12 10 4 HEAT repeat HEAT_2 PF13646.6 RLN73321.1 - 6.9e-15 55.2 6.0 0.018 15.4 0.0 7.6 6 3 1 7 7 7 4 HEAT repeats HEAT_EZ PF13513.6 RLN73321.1 - 8.3e-11 42.2 1.9 0.03 14.8 0.0 8.6 9 0 0 9 9 8 2 HEAT-like repeat CLASP_N PF12348.8 RLN73321.1 - 5.9e-07 29.3 1.0 0.17 11.4 0.0 5.2 4 1 2 6 6 6 3 CLASP N terminal Cnd1 PF12717.7 RLN73321.1 - 2.7e-05 24.3 7.6 0.016 15.3 0.0 5.9 6 2 0 6 6 5 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 RLN73321.1 - 3.7e-05 22.5 10.6 0.55 8.7 0.0 5.5 4 2 0 5 5 5 2 Adaptin N terminal region Sec7_N PF12783.7 RLN73321.1 - 0.00032 20.6 0.0 0.11 12.5 0.0 4.5 3 1 1 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal RTP1_C1 PF10363.9 RLN73321.1 - 0.0025 18.0 7.2 0.32 11.2 0.0 5.6 6 0 0 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_UF PF18817.1 RLN73321.1 - 0.015 15.6 0.2 0.22 11.8 0.1 2.9 3 0 0 3 3 3 0 Repeat of uncharacterized protein PH0542 ParcG PF10274.9 RLN73321.1 - 0.026 14.6 2.7 8.8 6.4 0.0 4.1 3 1 1 4 4 4 0 Parkin co-regulated protein DUF3385 PF11865.8 RLN73321.1 - 0.028 14.3 0.7 23 4.9 0.2 4.2 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) Arm PF00514.23 RLN73321.1 - 0.036 14.1 2.2 97 3.2 0.0 5.7 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Ipi1_N PF12333.8 RLN73321.1 - 0.048 14.3 1.0 14 6.3 0.0 4.1 4 0 0 4 4 3 0 Rix1 complex component involved in 60S ribosome maturation Choline_transpo PF04515.12 RLN73321.1 - 0.094 11.9 0.1 1.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Plasma-membrane choline transporter DUF4042 PF13251.6 RLN73321.1 - 1.8 8.2 5.6 33 4.1 0.0 5.1 6 1 0 6 6 6 0 Domain of unknown function (DUF4042) DUF1697 PF08002.11 RLN73322.1 - 2.2e-22 80.0 1.0 1.2e-21 77.6 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1697) Ras PF00071.22 RLN73323.1 - 3.7e-57 192.5 0.1 5.4e-57 191.9 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN73323.1 - 3.8e-32 111.0 0.1 6.8e-32 110.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN73323.1 - 1.9e-14 53.5 0.0 2.6e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RLN73323.1 - 8.1e-07 28.6 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RLN73323.1 - 7.1e-06 26.1 0.0 1.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RLN73323.1 - 0.00089 19.2 0.1 0.051 13.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 RLN73323.1 - 0.001 18.6 0.1 0.0046 16.5 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_5 PF07728.14 RLN73323.1 - 0.0052 16.8 0.0 0.013 15.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 RLN73323.1 - 0.019 15.1 0.1 0.038 14.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RLN73323.1 - 0.022 15.1 0.1 0.039 14.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 RLN73323.1 - 0.041 13.8 0.1 0.086 12.7 0.0 1.6 2 0 0 2 2 2 0 NTPase AAA_7 PF12775.7 RLN73323.1 - 0.068 12.7 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 RLN73323.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein SRPRB PF09439.10 RLN73323.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit LRR_6 PF13516.6 RLN73324.1 - 0.00056 19.8 0.7 13 6.1 0.0 4.0 4 0 0 4 4 4 2 Leucine Rich repeat IQ PF00612.27 RLN73324.1 - 0.0031 17.1 3.6 0.0031 17.1 3.6 10.9 11 0 0 11 11 11 5 IQ calmodulin-binding motif EF-hand_6 PF13405.6 RLN73324.1 - 0.013 15.4 0.1 0.035 14.0 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain Photo_RC PF00124.19 RLN73324.1 - 0.087 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Photosynthetic reaction centre protein Arm PF00514.23 RLN73325.1 - 8.4e-91 295.6 11.2 4e-12 45.7 0.1 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN73325.1 - 5.4e-24 84.3 0.8 1.1e-06 29.0 0.1 6.0 4 2 1 5 5 5 3 HEAT-like repeat HEAT_2 PF13646.6 RLN73325.1 - 2e-22 79.4 0.0 3.6e-06 27.3 0.0 6.1 2 2 2 5 5 5 4 HEAT repeats Arm_3 PF16186.5 RLN73325.1 - 9.3e-19 66.7 1.9 7e-18 63.9 2.0 2.2 2 0 0 2 2 2 1 Atypical Arm repeat HEAT PF02985.22 RLN73325.1 - 1.1e-16 59.5 1.0 9.6e-05 22.3 0.0 8.0 9 0 0 9 9 9 3 HEAT repeat IBB PF01749.20 RLN73325.1 - 1.4e-11 44.7 14.2 2e-08 34.6 7.8 3.0 2 1 1 3 3 3 2 Importin beta binding domain V-ATPase_H_C PF11698.8 RLN73325.1 - 2.9e-07 30.6 0.2 0.034 14.2 0.0 4.3 4 0 0 4 4 4 2 V-ATPase subunit H Arm_2 PF04826.13 RLN73325.1 - 9.2e-07 28.6 0.0 0.0015 18.0 0.0 2.8 1 1 1 3 3 3 2 Armadillo-like Adaptin_N PF01602.20 RLN73325.1 - 5.9e-06 25.1 0.0 1.3e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Adaptin N terminal region Mo25 PF08569.11 RLN73325.1 - 0.00037 20.0 0.1 0.75 9.1 0.0 2.3 2 0 0 2 2 2 2 Mo25-like HEAT_PBS PF03130.16 RLN73325.1 - 0.0011 19.4 1.1 1.4 9.8 0.0 5.2 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 RLN73325.1 - 0.0021 18.1 1.1 0.22 11.6 0.0 4.0 4 2 1 5 5 5 1 Spinocerebellar ataxia type 10 protein domain RICTOR_V PF14668.6 RLN73325.1 - 0.0077 16.5 4.3 25 5.2 0.1 5.0 4 2 2 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 Vac14_Fab1_bd PF12755.7 RLN73325.1 - 0.13 12.9 0.0 62 4.3 0.0 3.3 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region HSP33 PF01430.19 RLN73326.1 - 4.8e-34 118.0 0.0 1.1e-33 116.8 0.0 1.6 2 0 0 2 2 2 1 Hsp33 protein DUF3342 PF11822.8 RLN73326.1 - 2.2e-28 98.3 1.9 5e-28 97.2 1.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) BTB PF00651.31 RLN73326.1 - 8.6e-06 26.0 0.3 1.9e-05 24.9 0.3 1.5 1 0 0 1 1 1 1 BTB/POZ domain CCD PF07860.11 RLN73326.1 - 0.026 14.6 0.1 0.045 13.8 0.1 1.3 1 0 0 1 1 1 0 WisP family C-Terminal Region Nmad3 PF18754.1 RLN73326.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 MIT PF04212.18 RLN73327.1 - 1.8e-23 82.4 0.1 3.1e-23 81.6 0.1 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 RLN73327.1 - 0.022 14.8 0.1 0.06 13.5 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1840 PF08895.11 RLN73327.1 - 0.072 13.4 2.3 0.52 10.7 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) TPR_1 PF00515.28 RLN73327.1 - 0.26 11.2 0.3 0.26 11.2 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Pec_lyase_C PF00544.19 RLN73331.1 - 2.6e-11 43.5 8.8 3e-10 40.0 8.8 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 RLN73331.1 - 0.0023 17.8 2.4 0.0023 17.8 2.4 2.5 1 1 1 2 2 2 2 Right handed beta helix region CDC27 PF09507.10 RLN73331.1 - 0.37 10.1 10.1 0.51 9.7 10.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RR_TM4-6 PF06459.12 RLN73331.1 - 0.89 9.3 3.5 1.3 8.8 3.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CPSF100_C PF13299.6 RLN73331.1 - 5.2 7.2 5.4 9.3 6.4 5.4 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SKN1 PF03935.15 RLN73332.1 - 8.1e-61 205.9 24.7 2.7e-27 95.3 4.2 4.9 3 2 0 3 3 3 3 Beta-glucan synthesis-associated protein (SKN1) Nodulin_late PF07127.11 RLN73332.1 - 2.2 8.7 6.8 3.3 8.1 0.6 3.3 3 0 0 3 3 3 0 Late nodulin protein PepSY_2 PF13670.6 RLN73332.1 - 4.4 7.4 6.6 2.6 8.1 0.2 3.6 4 0 0 4 4 4 0 Peptidase propeptide and YPEB domain AFG1_ATPase PF03969.16 RLN73333.1 - 5.7e-91 305.1 3.4 8.6e-87 291.3 1.2 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 RLN73333.1 - 0.00025 21.5 0.3 0.00025 21.5 0.3 2.8 2 2 0 2 2 2 1 AAA ATPase domain Bac_DnaA PF00308.18 RLN73333.1 - 0.0004 20.3 0.1 0.093 12.5 0.0 2.3 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_22 PF13401.6 RLN73333.1 - 0.0041 17.4 0.2 0.026 14.8 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 RLN73333.1 - 0.026 15.0 0.0 0.81 10.1 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pex26 PF07163.12 RLN73334.1 - 0.0024 17.2 0.8 0.0035 16.7 0.8 1.2 1 0 0 1 1 1 1 Pex26 protein BAR PF03114.18 RLN73334.1 - 0.028 14.1 2.3 0.041 13.5 2.3 1.2 1 0 0 1 1 1 0 BAR domain PDCD2_C PF04194.13 RLN73335.1 - 3.4e-35 121.7 2.7 3.4e-34 118.4 0.0 2.3 2 1 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain DAO PF01266.24 RLN73336.1 - 5.1e-51 174.3 0.7 6.4e-51 174.0 0.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RLN73336.1 - 5e-05 23.5 0.1 0.00011 22.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 RLN73336.1 - 0.00014 21.4 1.0 0.00022 20.7 1.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RLN73336.1 - 0.0011 18.2 0.1 0.0066 15.7 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 RLN73336.1 - 0.0013 17.9 4.0 0.002 17.3 4.0 1.4 1 1 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 RLN73336.1 - 0.0026 17.1 0.1 0.0037 16.6 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 RLN73336.1 - 0.0091 14.7 0.7 0.013 14.2 0.7 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 RLN73336.1 - 0.014 14.7 0.4 0.024 13.9 0.4 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 RLN73336.1 - 0.02 14.2 0.3 0.04 13.2 0.3 1.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 RLN73336.1 - 0.024 14.0 0.1 0.037 13.4 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 RLN73336.1 - 0.025 14.5 0.6 0.04 13.8 0.6 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 RLN73336.1 - 0.027 15.0 0.5 0.048 14.2 0.5 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RLN73336.1 - 0.057 12.7 2.3 0.44 9.7 0.6 2.1 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 RLN73336.1 - 0.079 12.0 1.5 0.12 11.4 1.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A XdhC_C PF13478.6 RLN73336.1 - 0.13 12.8 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain TrkA_N PF02254.18 RLN73336.1 - 0.17 12.2 0.2 0.39 11.0 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain DUF5600 PF18150.1 RLN73337.1 - 9.7e-40 135.5 0.1 1.7e-39 134.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 RLN73337.1 - 2.8e-09 36.9 0.0 1e-08 35.1 0.0 1.9 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Dynamin_N PF00350.23 RLN73337.1 - 1.9e-06 28.1 0.0 2.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 RLN73337.1 - 0.00014 22.0 0.0 0.00029 20.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RLN73337.1 - 0.091 12.3 0.1 0.2 11.1 0.1 1.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain SMC_N PF02463.19 RLN73340.1 - 3.6e-29 101.8 0.5 5.6e-29 101.2 0.5 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RLN73340.1 - 6.6e-19 69.2 0.1 6.6e-19 69.2 0.1 4.1 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 RLN73340.1 - 1.9e-08 34.4 3.9 1.9e-08 34.4 3.9 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 RLN73340.1 - 3e-07 30.6 0.1 0.0003 20.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN73340.1 - 0.00012 21.8 0.0 0.00026 20.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Endotoxin_N PF03945.14 RLN73340.1 - 0.15 11.7 0.4 1.5 8.5 0.1 2.7 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain Img2 PF05046.14 RLN73340.1 - 3.4 8.0 7.5 50 4.3 1.1 4.5 4 1 0 4 4 4 0 Mitochondrial large subunit ribosomal protein (Img2) Nucleoside_tran PF01733.18 RLN73342.1 - 1.2e-30 107.0 12.1 1.2e-30 107.0 12.1 2.4 2 1 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.16 RLN73342.1 - 6.7e-05 22.0 40.5 0.018 14.0 20.9 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 RLN73342.1 - 0.17 12.2 7.1 0.076 13.3 0.5 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) DUF5090 PF17009.5 RLN73342.1 - 1.9 8.4 14.3 0.42 10.5 8.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) CoA_binding_3 PF13727.6 RLN73343.1 - 0.11 12.5 0.6 0.16 12.0 0.6 1.3 1 0 0 1 1 1 0 CoA-binding domain Yae1_N PF09811.9 RLN73348.1 - 1.3e-07 31.2 2.0 1.3e-07 31.2 2.0 2.0 3 0 0 3 3 3 1 Essential protein Yae1, N terminal Ufm1 PF03671.14 RLN73348.1 - 0.13 12.4 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin fold modifier 1 protein Ank_2 PF12796.7 RLN73350.1 - 3.5e-24 85.2 0.0 5.4e-13 49.4 0.0 3.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN73350.1 - 2.2e-14 53.6 3.0 4.2e-07 30.4 0.0 4.6 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN73350.1 - 1.2e-13 50.8 2.9 0.027 14.9 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 RLN73350.1 - 2.7e-13 48.8 3.9 0.046 14.3 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 RLN73350.1 - 1.2e-12 47.8 2.7 0.0096 16.2 0.0 5.2 4 1 1 5 5 5 5 Ankyrin repeats (many copies) PDZ_6 PF17820.1 RLN73350.1 - 1.5e-11 44.0 1.8 0.00012 21.8 1.0 2.8 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 RLN73350.1 - 2.2e-08 34.3 0.0 0.0093 16.3 0.0 2.8 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 RLN73350.1 - 0.00014 22.1 0.1 0.11 12.9 0.2 2.7 2 0 0 2 2 2 2 PDZ domain GRASP55_65 PF04495.14 RLN73350.1 - 0.00042 20.6 0.0 0.032 14.5 0.0 2.4 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain Pkinase PF00069.25 RLN73354.1 - 3.4e-49 167.6 0.0 6.1e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN73354.1 - 1.3e-43 149.2 0.0 2.2e-43 148.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Bact_lectin PF18483.1 RLN73354.1 - 3.7e-16 59.7 0.7 6.5e-16 58.9 0.0 1.7 2 0 0 2 2 2 1 Bacterial lectin Dimer_Tnp_hAT PF05699.14 RLN73354.1 - 3.2e-14 52.5 0.5 8.3e-14 51.2 0.5 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Lectin_legB PF00139.19 RLN73354.1 - 1.1e-08 35.0 0.0 2.7e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Legume lectin domain EphA2_TM PF14575.6 RLN73354.1 - 0.025 15.4 0.0 0.51 11.3 0.0 2.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Haspin_kinase PF12330.8 RLN73354.1 - 0.045 12.7 0.0 0.078 11.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF99 PF01949.16 RLN73354.1 - 0.15 11.5 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF99 ABC2_membrane PF01061.24 RLN73355.1 - 1.7e-33 115.8 11.9 2.3e-33 115.4 11.9 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN73355.1 - 1.7e-22 80.4 0.0 2.7e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN73355.1 - 4e-07 30.2 0.0 0.012 15.4 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN73355.1 - 9.6e-05 22.8 0.1 0.00024 21.5 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 RLN73355.1 - 0.00021 20.5 5.4 0.00021 20.5 5.4 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 RLN73355.1 - 0.00066 19.6 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN73355.1 - 0.0063 16.2 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 RLN73355.1 - 0.049 13.1 0.1 3.2 7.1 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 RLN73355.1 - 0.068 12.7 0.1 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 RLN73355.1 - 0.18 12.0 0.0 0.52 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 RLN73355.1 - 0.21 11.6 0.2 0.54 10.3 0.1 1.7 2 0 0 2 2 2 0 Dynamin family MMR_HSR1 PF01926.23 RLN73355.1 - 0.25 11.5 0.1 0.5 10.5 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 RLN73355.1 - 0.25 11.8 0.0 0.4 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Syntaphilin PF15290.6 RLN73362.1 - 0.00014 21.6 9.9 0.00014 21.6 9.9 2.4 2 1 1 3 3 3 1 Golgi-localised syntaxin-1-binding clamp Serglycin PF04360.12 RLN73362.1 - 0.0034 17.3 0.0 0.0066 16.4 0.0 1.5 1 0 0 1 1 1 1 Serglycin PKcGMP_CC PF16808.5 RLN73362.1 - 0.0048 16.7 11.5 0.0067 16.3 0.8 4.1 4 1 1 5 5 5 1 Coiled-coil N-terminus of cGMP-dependent protein kinase CENP-F_leu_zip PF10473.9 RLN73362.1 - 0.01 15.9 5.2 0.01 15.9 5.2 3.1 3 0 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HlyD_2 PF12700.7 RLN73362.1 - 0.045 12.5 1.5 0.061 12.1 1.4 1.3 1 1 0 1 1 1 0 HlyD family secretion protein EzrA PF06160.12 RLN73362.1 - 0.05 11.8 7.8 0.02 13.1 5.3 1.6 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF812 PF05667.11 RLN73362.1 - 0.051 12.5 12.3 0.62 8.9 0.7 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF812) SlyX PF04102.12 RLN73362.1 - 0.078 13.6 20.3 0.34 11.5 0.0 4.6 3 2 1 4 4 4 0 SlyX TolA_bind_tri PF16331.5 RLN73362.1 - 0.18 11.9 18.9 1.1 9.4 0.7 4.4 4 1 0 4 4 4 0 TolA binding protein trimerisation DUF1664 PF07889.12 RLN73362.1 - 0.44 10.6 8.9 0.26 11.3 1.7 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF5082 PF16888.5 RLN73362.1 - 0.46 10.8 14.0 0.38 11.0 1.0 4.1 2 2 1 3 3 3 0 Domain of unknown function (DUF5082) Fib_alpha PF08702.10 RLN73362.1 - 0.64 10.2 13.9 0.33 11.2 4.9 3.1 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 RLN73362.1 - 0.76 10.2 14.8 6.5 7.2 14.8 2.3 1 1 0 1 1 1 0 Fez1 ATG16 PF08614.11 RLN73362.1 - 1.1 9.4 18.1 0.16 12.2 5.4 2.6 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF16 PF01519.16 RLN73362.1 - 1.5 9.3 10.8 12 6.5 4.2 3.5 3 1 0 3 3 3 0 Protein of unknown function DUF16 Prefoldin PF02996.17 RLN73362.1 - 1.8 8.5 11.7 0.14 12.1 1.1 3.8 3 2 1 4 4 4 0 Prefoldin subunit Atg14 PF10186.9 RLN73362.1 - 1.9 7.5 18.7 0.1 11.7 6.8 2.3 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaC_arch PF05377.11 RLN73362.1 - 1.9 8.9 7.7 32 5.0 1.8 3.7 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Lebercilin PF15619.6 RLN73362.1 - 2 8.0 21.6 1.1 8.9 6.6 3.4 3 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease CALCOCO1 PF07888.11 RLN73362.1 - 2.1 7.1 19.0 0.027 13.3 5.9 2.3 2 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Spc29 PF17082.5 RLN73362.1 - 2.8 7.7 12.9 25 4.6 10.7 3.0 2 1 0 2 2 2 0 Spindle Pole Component 29 TMF_DNA_bd PF12329.8 RLN73362.1 - 3.6 7.6 19.6 4.9 7.2 7.2 4.6 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Med4 PF10018.9 RLN73362.1 - 4.6 6.9 9.8 1.2e+02 2.3 7.3 3.2 2 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Bcr-Abl_Oligo PF09036.10 RLN73362.1 - 4.6 7.3 7.2 1.2 9.2 1.1 3.0 2 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Spc7 PF08317.11 RLN73362.1 - 4.8 6.0 17.5 0.089 11.7 4.2 2.6 2 1 0 2 2 2 0 Spc7 kinetochore protein TMPIT PF07851.13 RLN73362.1 - 5.2 6.2 10.3 0.4 9.9 4.0 2.0 2 0 0 2 2 2 0 TMPIT-like protein ADH_zinc_N PF00107.26 RLN73363.1 - 3.4e-16 59.4 0.0 6.6e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN73363.1 - 1.9e-12 47.0 0.7 1.9e-12 47.0 0.7 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 RLN73363.1 - 0.00019 20.8 0.0 0.00035 20.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN73363.1 - 0.0024 17.2 0.8 0.039 13.2 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DUF364 PF04016.12 RLN73363.1 - 0.0071 15.9 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Putative heavy-metal chelation NAD_binding_2 PF03446.15 RLN73363.1 - 0.06 13.5 0.1 0.24 11.5 0.0 1.9 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase PAP2 PF01569.21 RLN73365.1 - 5.9e-22 77.9 8.2 1.2e-21 77.0 8.2 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 RLN73365.1 - 5e-05 23.8 3.2 5e-05 23.8 3.2 2.2 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2_3 PF14378.6 RLN73365.1 - 5.2e-05 23.0 13.6 0.00013 21.8 9.6 2.7 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 RLN73365.1 - 0.16 12.1 0.4 5.2 7.2 0.1 2.3 1 1 1 2 2 2 0 Divergent PAP2 family IQ PF00612.27 RLN73367.1 - 1.7e-46 151.7 41.6 0.0067 16.1 0.0 16.6 16 0 0 16 16 16 16 IQ calmodulin-binding motif SPOC PF07744.13 RLN73367.1 - 0.0037 17.2 0.1 0.66 9.9 0.0 4.2 5 2 0 5 5 5 1 SPOC domain Zot PF05707.12 RLN73367.1 - 0.97 9.0 5.8 13 5.4 0.1 3.3 1 1 1 3 3 3 0 Zonular occludens toxin (Zot) p450 PF00067.22 RLN73371.1 - 1e-82 278.4 0.0 1.2e-82 278.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3522 PF12036.8 RLN73372.1 - 7.1e-22 78.6 0.0 8.4e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) Ceramidase PF05875.12 RLN73372.1 - 0.081 12.3 0.1 0.18 11.2 0.1 1.5 1 0 0 1 1 1 0 Ceramidase Pkinase PF00069.25 RLN73373.1 - 1.6e-53 181.8 0.0 5.2e-50 170.3 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN73373.1 - 1.5e-24 86.7 0.0 2.2e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN73373.1 - 1e-05 24.5 0.0 1.3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN73373.1 - 2e-05 24.1 0.0 3.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN73373.1 - 0.00019 21.4 3.6 0.001 19.1 3.6 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN73373.1 - 0.0015 17.9 1.6 0.0034 16.8 1.6 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TAP42 PF04177.12 RLN73373.1 - 0.03 13.5 1.2 0.042 13.0 1.2 1.1 1 0 0 1 1 1 0 TAP42-like family DUF3128 PF11326.8 RLN73377.1 - 7.8e-18 64.6 0.7 1.5e-17 63.8 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) UCR_14kD PF02271.16 RLN73378.1 - 1.6e-22 79.4 0.6 3.6e-22 78.2 0.6 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF4746 PF15928.5 RLN73378.1 - 0.13 11.7 7.2 0.14 11.6 6.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4746) PTPRCAP PF15713.5 RLN73378.1 - 1.5 9.1 11.4 0.45 10.8 8.3 1.8 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated YL1 PF05764.13 RLN73378.1 - 3.7 7.6 19.4 2.1 8.4 17.5 1.5 1 1 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 RLN73378.1 - 5 5.3 9.9 5.7 5.1 9.9 1.2 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.10 RLN73378.1 - 5.3 7.5 11.8 4 7.9 9.7 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain AAA_6 PF12774.7 RLN73379.1 - 8.8e-129 429.1 0.5 8e-113 376.7 0.0 3.4 2 1 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN73379.1 - 2.2e-118 395.9 5.8 2.6e-117 392.3 0.1 3.7 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RLN73379.1 - 2.3e-76 256.5 0.0 6.4e-76 255.1 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RLN73379.1 - 1.3e-72 243.5 13.5 1.7e-72 243.1 6.6 3.5 3 0 0 3 3 3 1 ATP-binding dynein motor region Dynein_C PF18199.1 RLN73379.1 - 3.9e-59 200.4 3.2 9e-58 195.9 0.6 2.9 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain MT PF12777.7 RLN73379.1 - 3.1e-51 174.4 12.1 6.7e-51 173.3 12.1 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 RLN73379.1 - 3.8e-50 169.9 0.0 3e-42 144.2 0.0 5.3 4 2 0 4 4 4 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 RLN73379.1 - 2e-40 137.6 3.5 2.4e-38 130.9 0.0 4.1 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 RLN73379.1 - 1.7e-37 128.7 0.0 7e-37 126.8 0.0 2.1 1 1 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 RLN73379.1 - 1.8e-13 50.7 0.0 7.3e-13 48.7 0.0 2.2 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RLN73379.1 - 5.5e-13 49.1 0.0 0.0019 18.2 0.0 6.0 5 2 0 5 5 4 2 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 RLN73379.1 - 4.6e-10 39.6 0.0 8.4e-09 35.6 0.0 3.0 2 1 0 2 2 2 1 AAA+ lid domain AAA_18 PF13238.6 RLN73379.1 - 1.7e-09 38.3 11.6 0.00036 21.1 0.0 6.9 8 0 0 8 8 6 2 AAA domain AAA_22 PF13401.6 RLN73379.1 - 4.2e-09 36.8 3.7 0.053 13.8 0.0 5.9 5 0 0 5 5 5 2 AAA domain AAA_29 PF13555.6 RLN73379.1 - 9e-06 25.3 0.2 0.088 12.6 0.0 3.5 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA PF00004.29 RLN73379.1 - 9.5e-06 26.1 1.5 0.019 15.4 0.0 4.2 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 RLN73379.1 - 0.0004 20.7 0.1 9.4 6.4 0.0 4.1 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 RLN73379.1 - 0.00046 20.5 0.0 18 5.7 0.0 3.8 3 0 0 3 3 3 0 RNA helicase T2SSE PF00437.20 RLN73379.1 - 0.00085 18.5 2.2 0.1 11.6 0.0 3.2 3 0 0 3 3 2 1 Type II/IV secretion system protein AAA_33 PF13671.6 RLN73379.1 - 0.00098 19.3 0.1 1.4 9.1 0.0 3.9 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 RLN73379.1 - 0.0043 17.6 3.1 5.5 7.5 0.0 4.5 5 0 0 5 5 3 1 ABC transporter AAA_16 PF13191.6 RLN73379.1 - 0.0051 17.2 15.0 0.21 11.9 0.0 6.6 6 1 0 6 6 5 1 AAA ATPase domain Rad17 PF03215.15 RLN73379.1 - 0.0072 16.3 0.2 20 5.0 0.0 4.3 4 0 0 4 4 4 0 Rad17 P-loop domain AAA_30 PF13604.6 RLN73379.1 - 0.015 15.1 10.8 0.33 10.6 0.0 4.8 4 0 0 4 4 3 0 AAA domain Ploopntkinase3 PF18751.1 RLN73379.1 - 0.05 13.5 0.1 0.57 10.1 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 NACHT PF05729.12 RLN73379.1 - 0.053 13.4 0.4 3.4 7.6 0.0 3.4 3 0 0 3 3 2 0 NACHT domain DUF815 PF05673.13 RLN73379.1 - 0.053 12.7 0.1 6.9 5.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_21 PF13304.6 RLN73379.1 - 0.084 12.7 0.0 3.9 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TsaE PF02367.17 RLN73379.1 - 0.1 12.6 0.4 32 4.6 0.0 3.5 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 RLN73379.1 - 0.11 12.3 0.5 11 5.7 0.0 3.1 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase Sec34 PF04136.15 RLN73379.1 - 0.16 11.8 6.8 0.13 12.2 1.5 3.3 2 0 0 2 2 2 0 Sec34-like family DUF87 PF01935.17 RLN73379.1 - 0.22 11.6 3.4 4.1 7.4 0.0 3.6 3 0 0 3 3 2 0 Helicase HerA, central domain AMMECR1 PF01871.17 RLN73380.1 - 1.1e-41 142.2 0.0 1.3e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 UvrB PF12344.8 RLN73380.1 - 0.18 11.7 0.1 0.42 10.5 0.1 1.6 1 0 0 1 1 1 0 Ultra-violet resistance protein B Kinesin PF00225.23 RLN73381.1 - 8.1e-102 340.6 4.8 5.7e-101 337.8 0.0 3.0 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 RLN73381.1 - 7.7e-25 87.6 0.0 3.5e-24 85.4 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding Myb_DNA-binding PF00249.31 RLN73386.1 - 3.6e-08 33.5 0.0 0.0036 17.4 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN73386.1 - 9.8e-07 28.9 0.0 0.0023 18.1 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 RLN73386.1 - 0.018 15.1 0.5 14 5.8 0.1 3.1 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Arm PF00514.23 RLN73387.1 - 4.1e-53 175.9 38.3 0.011 15.7 0.0 18.3 18 1 0 18 18 18 15 Armadillo/beta-catenin-like repeat Pkinase_Tyr PF07714.17 RLN73387.1 - 1.3e-42 145.9 0.0 2.3e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN73387.1 - 6.1e-36 124.1 0.0 1.3e-35 123.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Prok-E2_C PF14459.6 RLN73387.1 - 1.4e-09 38.2 28.2 0.41 10.8 0.1 10.3 1 1 11 12 12 12 4 Prokaryotic E2 family C Arm_2 PF04826.13 RLN73387.1 - 8.1e-07 28.7 0.1 1.6 8.1 0.0 6.7 5 1 1 8 8 8 1 Armadillo-like HEAT PF02985.22 RLN73387.1 - 2.3e-06 27.4 29.5 42 4.8 0.0 14.2 15 0 0 15 15 15 0 HEAT repeat RICTOR_N PF14664.6 RLN73387.1 - 2.3e-05 23.6 0.0 0.89 8.5 0.0 4.8 4 1 2 6 6 6 1 Rapamycin-insensitive companion of mTOR, N-term ABC1 PF03109.16 RLN73387.1 - 0.0034 17.5 0.0 0.0087 16.2 0.0 1.6 1 0 0 1 1 1 1 ABC1 family DZR PF12773.7 RLN73387.1 - 0.0049 16.9 0.2 0.01 15.8 0.2 1.4 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 RLN73387.1 - 0.064 14.0 0.1 0.13 13.1 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon family aGPT-Pplase2 PF18724.1 RLN73387.1 - 0.067 13.0 4.4 4.3 7.1 0.1 5.2 4 2 5 9 9 9 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 2 Peptidase_M13_N PF05649.13 RLN73389.1 - 7.5e-71 239.8 0.0 1.3e-70 239.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Pkinase PF00069.25 RLN73389.1 - 3.4e-69 233.1 0.0 5.2e-69 232.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Peptidase_M13 PF01431.21 RLN73389.1 - 4.2e-58 196.3 0.0 8.1e-58 195.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 Pkinase_Tyr PF07714.17 RLN73389.1 - 5.6e-33 114.3 0.1 9.4e-33 113.6 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_1 PF00536.30 RLN73389.1 - 7.8e-14 51.9 0.1 2e-13 50.6 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RLN73389.1 - 1.1e-10 41.4 0.1 2.8e-10 40.2 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EF-hand_1 PF00036.32 RLN73389.1 - 0.00025 20.4 0.0 0.0019 17.6 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 RLN73389.1 - 0.00032 21.1 0.1 0.0079 16.6 0.0 3.3 3 0 0 3 3 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN73389.1 - 0.00035 20.3 0.1 0.0018 18.0 0.1 2.3 1 0 0 1 1 1 1 EF-hand domain dCMP_cyt_deam_1 PF00383.23 RLN73389.1 - 0.0014 18.5 0.3 0.0039 17.0 0.3 1.8 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF1325 PF07039.11 RLN73389.1 - 0.017 15.2 0.1 0.07 13.2 0.1 2.1 2 0 0 2 2 2 0 SGF29 tudor-like domain Agenet PF05641.12 RLN73389.1 - 0.028 14.9 0.0 0.088 13.3 0.0 2.0 1 0 0 1 1 1 0 Agenet domain EF-hand_5 PF13202.6 RLN73389.1 - 0.059 12.9 0.9 0.22 11.1 0.9 2.1 1 0 0 1 1 1 0 EF hand SAM_PNT PF02198.16 RLN73389.1 - 0.068 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Haspin_kinase PF12330.8 RLN73389.1 - 0.083 11.8 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain GREB1 PF15782.5 RLN73389.1 - 7.9 3.4 8.8 14 2.6 8.8 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RNA_pol_Rpb5_C PF01191.19 RLN73390.1 - 9.7e-32 108.7 0.1 2.1e-31 107.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 RLN73390.1 - 1.6e-23 83.0 0.0 5.7e-23 81.3 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain PAN_4 PF14295.6 RLN73398.1 - 0.12 12.3 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 PAN domain MIP PF00230.20 RLN73399.1 - 2.2e-54 184.6 7.6 3e-54 184.1 7.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein Phage_holin_8 PF16931.5 RLN73399.1 - 0.044 13.8 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 Putative phage holin DUF4064 PF13273.6 RLN73399.1 - 0.073 13.4 1.0 0.51 10.6 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Polysacc_synt_C PF14667.6 RLN73399.1 - 1.2 9.2 7.6 3.2 7.8 0.1 3.1 3 0 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain Ank_2 PF12796.7 RLN73404.1 - 3.8e-13 49.8 0.2 3.9e-06 27.4 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RLN73404.1 - 3e-11 43.2 0.3 1.5e-05 25.2 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RLN73404.1 - 4.4e-09 36.4 1.4 2.2e-05 24.6 0.4 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN73404.1 - 7.5e-09 36.0 0.6 0.00051 20.5 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN73404.1 - 1.1e-07 31.6 0.1 0.031 14.8 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat zf-C3HC4_3 PF13920.6 RLN73405.1 - 1.4e-12 47.3 7.8 2.2e-12 46.7 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN73405.1 - 7.6e-11 41.7 7.3 1.4e-10 40.9 7.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN73405.1 - 5.1e-07 29.6 7.1 9.6e-07 28.7 7.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 RLN73405.1 - 9e-07 29.1 8.1 1.6e-06 28.3 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN73405.1 - 7.6e-06 25.7 8.2 1.3e-05 24.9 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN73405.1 - 9.1e-06 25.4 7.3 1.8e-05 24.5 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN73405.1 - 0.00013 21.9 7.4 0.00023 21.1 2.0 2.7 3 0 0 3 3 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 RLN73405.1 - 0.0079 16.0 4.6 0.015 15.1 4.6 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 RLN73405.1 - 0.011 15.9 8.8 0.054 13.6 9.0 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 RLN73405.1 - 0.042 14.1 3.6 0.086 13.1 3.6 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Rtf2 PF04641.12 RLN73405.1 - 0.13 11.6 0.5 0.2 11.0 0.5 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger CcdA PF07362.12 RLN73405.1 - 0.24 11.8 1.6 0.52 10.8 1.6 1.5 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA DUF1272 PF06906.11 RLN73405.1 - 0.24 11.5 3.9 0.54 10.4 3.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4379 PF14311.6 RLN73405.1 - 0.31 11.4 4.4 0.72 10.3 4.4 1.6 1 0 0 1 1 1 0 Probable Zinc-ribbon domain DZR PF12773.7 RLN73405.1 - 2.8 8.0 7.9 8 6.6 8.1 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_11 PF17123.5 RLN73405.1 - 5.9 6.7 6.6 9.4 6.1 3.4 2.5 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_5 PF17121.5 RLN73405.1 - 6.1 6.8 7.0 32 4.5 7.0 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ank_4 PF13637.6 RLN73406.1 - 1.1e-13 51.4 0.3 5.2e-08 33.3 0.0 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 RLN73406.1 - 1.8e-13 50.1 12.9 3.4e-13 49.2 12.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.6 RLN73406.1 - 2.4e-11 43.7 0.2 1.4e-07 31.6 0.3 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.29 RLN73406.1 - 5.1e-11 43.0 0.1 1.4e-10 41.6 0.1 1.7 2 0 0 2 2 2 1 PH domain Ank_2 PF12796.7 RLN73406.1 - 2.5e-10 40.8 0.2 0.00067 20.2 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RLN73406.1 - 6e-09 36.0 0.4 0.0036 17.7 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeat Prok-RING_4 PF14447.6 RLN73406.1 - 7.6e-06 25.7 12.5 1.4e-05 24.8 12.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 RLN73406.1 - 1.1e-05 25.6 14.2 1.1e-05 25.6 14.2 2.0 2 0 0 2 2 2 1 Ring finger domain Ank_3 PF13606.6 RLN73406.1 - 1.6e-05 24.9 0.1 0.34 11.6 0.1 3.5 4 0 0 4 4 3 2 Ankyrin repeat zf-C3HC4 PF00097.25 RLN73406.1 - 3.1e-05 23.7 14.7 7e-05 22.6 14.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN73406.1 - 0.0013 18.5 14.2 0.0025 17.6 14.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN73406.1 - 0.15 12.0 16.3 0.039 13.9 12.7 1.9 2 0 0 2 2 2 0 zinc-RING finger domain COX15-CtaA PF02628.15 RLN73414.1 - 4.3e-104 348.1 3.8 5.1e-104 347.8 3.8 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF5337 PF17272.2 RLN73414.1 - 1 9.2 3.5 1.5 8.7 0.2 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5337) Hydrolase_4 PF12146.8 RLN73415.1 - 5.6e-13 48.7 0.0 9.9e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN73415.1 - 3.1e-08 33.6 0.1 1.3e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 RLN73415.1 - 4e-06 26.6 0.0 9.1e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Armet PF10208.9 RLN73415.1 - 0.0014 18.6 0.1 0.0025 17.7 0.1 1.4 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding Abhydrolase_6 PF12697.7 RLN73415.1 - 0.0025 18.5 0.0 0.0044 17.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 RLN73415.1 - 0.0028 16.4 0.0 0.02 13.6 0.0 1.9 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Asp2 PF16929.5 RLN73415.1 - 0.18 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter IMUP PF15761.5 RLN73416.1 - 1.8 9.3 8.3 3 8.6 8.3 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Tyr-DNA_phospho PF06087.12 RLN73418.1 - 7.7e-65 219.4 0.0 1.3e-32 113.3 0.1 2.0 2 0 0 2 2 2 2 Tyrosyl-DNA phosphodiesterase Lipase PF00151.19 RLN73418.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipase Med8 PF10232.9 RLN73419.1 - 4.7e-08 32.9 5.5 1.6e-07 31.2 5.5 1.7 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 MULE PF10551.9 RLN73420.1 - 0.00012 22.4 0.2 0.004 17.5 0.0 2.9 2 0 0 2 2 2 1 MULE transposase domain SWIM PF04434.17 RLN73420.1 - 0.0005 19.7 0.2 0.0015 18.2 0.2 1.7 1 0 0 1 1 1 1 SWIM zinc finger DBD_Tnp_Mut PF03108.15 RLN73420.1 - 0.029 14.3 9.6 0.082 12.9 0.1 3.0 3 0 0 3 3 3 0 MuDR family transposase AFT PF08731.11 RLN73420.1 - 0.12 12.8 1.8 6.5 7.2 0.0 2.5 2 0 0 2 2 2 0 Transcription factor AFT TFIID_20kDa PF03847.13 RLN73421.1 - 6.4e-20 71.4 0.0 1.1e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 RLN73421.1 - 0.012 15.6 0.0 0.03 14.4 0.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit TFIID-18kDa PF02269.16 RLN73421.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit SecA_DEAD PF07517.14 RLN73427.1 - 1.4e-27 96.7 0.0 3e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_PP_bind PF01043.20 RLN73427.1 - 0.0001 22.9 0.0 0.00029 21.4 0.0 1.8 1 0 0 1 1 1 1 SecA preprotein cross-linking domain DEAD PF00270.29 RLN73427.1 - 0.028 14.2 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase GED PF02212.18 RLN73428.1 - 0.041 14.0 1.0 0.041 14.0 1.0 3.2 3 1 1 4 4 4 0 Dynamin GTPase effector domain FAD-oxidase_C PF02913.19 RLN73432.1 - 3.1e-43 148.2 0.2 6.4e-43 147.2 0.0 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 RLN73432.1 - 2.5e-37 127.7 0.1 5.4e-37 126.6 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain IU_nuc_hydro PF01156.19 RLN73432.1 - 0.032 13.8 0.0 0.8 9.2 0.0 2.2 2 0 0 2 2 2 0 Inosine-uridine preferring nucleoside hydrolase NINJA_B PF16136.5 RLN73433.1 - 0.0078 16.6 6.9 0.025 14.9 6.9 1.9 1 0 0 1 1 1 1 Putative nuclear localisation signal ADH_N PF08240.12 RLN73434.1 - 8.5e-09 35.3 0.0 1.1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PDZ_6 PF17820.1 RLN73443.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 RLN73443.1 - 0.037 14.4 0.1 0.091 13.1 0.1 1.6 1 0 0 1 1 1 0 PDZ domain MMR_HSR1 PF01926.23 RLN73446.1 - 1.7e-09 37.8 0.0 3.1e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 RLN73446.1 - 1.3e-08 34.4 0.1 1.9e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 RLN73446.1 - 0.00056 19.8 0.1 0.0015 18.5 0.1 1.6 1 1 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 RLN73446.1 - 0.0012 19.4 0.0 0.0021 18.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 RLN73446.1 - 0.0032 16.9 0.0 0.0064 15.9 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.6 RLN73446.1 - 0.0037 17.0 0.3 0.0085 15.8 0.0 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN73446.1 - 0.0071 16.8 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 RLN73446.1 - 0.018 15.1 2.4 0.27 11.3 0.2 2.7 2 1 0 3 3 3 0 Dynamin family FeoB_N PF02421.18 RLN73446.1 - 0.02 14.4 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.29 RLN73446.1 - 0.061 13.8 0.1 0.11 12.9 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 RLN73446.1 - 0.062 13.0 0.8 0.37 10.5 0.8 2.1 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 RLN73446.1 - 0.16 11.3 2.0 1.4 8.3 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Pectate_lyase PF03211.13 RLN73453.1 - 3.5e-79 265.1 4.8 7.7e-79 264.0 4.8 1.6 1 0 0 1 1 1 1 Pectate lyase Astacin PF01400.24 RLN73454.1 - 2.4e-23 82.7 10.1 4.5e-20 72.1 2.9 3.4 3 1 0 3 3 3 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 RLN73454.1 - 0.0027 18.2 2.5 0.025 15.1 0.0 2.6 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 RLN73454.1 - 0.0056 15.4 0.2 0.01 14.5 0.2 1.4 1 0 0 1 1 1 1 Putative peptidase family Mucin PF01456.17 RLN73454.1 - 0.007 16.4 1.4 0.021 14.8 1.4 1.8 1 0 0 1 1 1 1 Mucin-like glycoprotein Peptidase_M10 PF00413.24 RLN73454.1 - 0.063 13.1 6.8 0.25 11.2 4.7 2.6 2 1 0 2 2 2 0 Matrixin FAM176 PF14851.6 RLN73454.1 - 0.39 10.4 4.7 0.24 11.0 1.5 2.0 2 0 0 2 2 2 0 FAM176 family PPP4R2 PF09184.11 RLN73454.1 - 0.41 10.2 5.6 0.7 9.4 5.6 1.3 1 0 0 1 1 1 0 PPP4R2 MULE PF10551.9 RLN73455.1 - 1.1e-13 51.4 0.0 2.6e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Kazal_1 PF00050.21 RLN73456.1 - 1.8e-07 31.1 0.3 3.1e-07 30.3 0.3 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 RLN73456.1 - 2e-05 24.6 0.2 3.3e-05 23.9 0.2 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain tRNA_edit PF04073.15 RLN73457.1 - 4.4e-22 78.4 0.5 1.1e-21 77.2 0.5 1.7 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain ProRS-C_1 PF09180.11 RLN73457.1 - 1.5e-21 76.4 1.3 3.5e-21 75.2 1.3 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 RLN73457.1 - 1.3e-18 67.6 0.0 2.7e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 RLN73457.1 - 8e-17 61.2 0.0 2.1e-16 59.8 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain Ribosomal_60s PF00428.19 RLN73457.1 - 0.093 13.3 6.7 0.15 12.6 4.5 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein WD40 PF00400.32 RLN73458.1 - 2.4e-11 44.0 19.7 5.5e-05 23.9 0.3 9.3 10 0 0 10 10 10 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 RLN73458.1 - 0.005 15.6 0.0 0.44 9.2 0.0 3.0 3 0 0 3 3 3 1 Nup133 N terminal like ANAPC4_WD40 PF12894.7 RLN73458.1 - 0.16 12.3 0.0 5.1 7.5 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Pectate_lyase PF03211.13 RLN73459.1 - 7e-79 264.1 4.8 7e-79 264.1 4.8 1.8 2 0 0 2 2 2 1 Pectate lyase Podoplanin PF05808.11 RLN73459.1 - 1.4 9.0 31.3 0.7 10.0 27.7 2.3 2 0 0 2 2 2 0 Podoplanin PPP4R2 PF09184.11 RLN73459.1 - 2.3 7.7 41.5 3.7 7.1 41.5 1.4 1 0 0 1 1 1 0 PPP4R2 Hamartin PF04388.12 RLN73459.1 - 3.8 6.1 16.6 4.2 5.9 16.6 1.1 1 0 0 1 1 1 0 Hamartin protein SET PF00856.28 RLN73460.1 - 0.00055 20.4 2.8 0.00056 20.3 0.0 2.2 2 1 0 2 2 2 1 SET domain bZIP_1 PF00170.21 RLN73461.1 - 0.2 11.8 12.7 1.2 9.3 12.7 2.0 1 1 0 1 1 1 0 bZIP transcription factor CALM_bind PF16025.5 RLN73461.1 - 0.21 12.1 5.4 0.61 10.6 5.4 1.9 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding bZIP_2 PF07716.15 RLN73461.1 - 0.21 11.7 16.0 0.045 13.8 9.1 2.2 1 1 1 2 2 2 0 Basic region leucine zipper Acyl-CoA_dh_1 PF00441.24 RLN73462.1 - 4.5e-50 169.8 2.8 7.6e-50 169.0 2.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RLN73462.1 - 8.2e-26 90.9 0.1 2.5e-25 89.3 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 RLN73462.1 - 8.9e-26 89.9 0.2 1.8e-25 89.0 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RLN73462.1 - 3.6e-20 72.6 0.7 5.7e-20 71.9 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 RLN73462.1 - 0.00027 20.7 0.9 0.0014 18.4 0.8 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Kazal_1 PF00050.21 RLN73463.1 - 0.00021 21.3 0.4 0.00033 20.6 0.4 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 RLN73463.1 - 0.00028 20.9 0.5 0.00028 20.9 0.5 1.6 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain DUF5039 PF16442.5 RLN73463.1 - 0.028 14.0 0.5 0.05 13.2 0.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5039) TolA_bind_tri PF16331.5 RLN73467.1 - 0.05 13.7 1.8 0.11 12.6 1.8 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation SKA2 PF16740.5 RLN73467.1 - 0.089 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 DivIC PF04977.15 RLN73467.1 - 0.3 10.9 1.7 0.95 9.3 0.9 2.1 2 0 0 2 2 2 0 Septum formation initiator HisKA_3 PF07730.13 RLN73470.1 - 0.035 14.6 0.8 2 9.0 0.1 2.6 2 0 0 2 2 2 0 Histidine kinase Annexin PF00191.20 RLN73473.1 - 1.1e-22 79.9 0.0 1.4e-10 41.1 0.0 2.7 3 0 0 3 3 3 2 Annexin Annexin PF00191.20 RLN73474.1 - 8.1e-50 166.8 0.0 2.3e-12 46.8 0.0 4.2 4 0 0 4 4 4 4 Annexin Pkinase PF00069.25 RLN73475.1 - 5.6e-56 189.8 0.0 1.3e-55 188.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN73475.1 - 2.7e-29 102.3 0.0 3.7e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN73475.1 - 2.7e-06 26.9 0.0 3.8e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN73475.1 - 0.0041 16.5 0.0 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_head_chap PF11113.8 RLN73475.1 - 0.076 13.1 0.0 0.32 11.1 0.0 2.1 2 0 0 2 2 2 0 Head assembly gene product APH PF01636.23 RLN73475.1 - 0.11 12.3 0.0 1.4 8.7 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF773 PF05600.12 RLN73476.1 - 2.2e-81 274.1 0.0 8.8e-67 226.0 0.0 2.1 2 0 0 2 2 2 2 CDK5 regulatory subunit-associated protein 3 SHE3 PF17078.5 RLN73476.1 - 0.05 13.3 0.4 0.093 12.4 0.4 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 ATG16 PF08614.11 RLN73476.1 - 6.7 6.9 8.5 0.85 9.8 1.1 2.9 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) MF_alpha_N PF05436.11 RLN73477.1 - 1 9.3 4.2 0.52 10.3 0.1 2.2 1 1 1 2 2 2 0 Mating factor alpha precursor N-terminus Phage_integrase PF00589.22 RLN73481.1 - 0.076 12.8 0.0 0.68 9.7 0.0 2.4 2 1 0 3 3 3 0 Phage integrase family B56 PF01603.20 RLN73482.1 - 3e-91 306.5 0.5 4.2e-91 306.0 0.5 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PH PF00169.29 RLN73482.1 - 2.6e-06 27.9 1.6 0.00013 22.4 0.2 2.5 1 1 1 2 2 2 2 PH domain PH_11 PF15413.6 RLN73482.1 - 0.032 14.7 0.0 0.08 13.4 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain TMEM219 PF14940.6 RLN73482.1 - 0.051 13.1 0.1 0.087 12.4 0.1 1.3 1 0 0 1 1 1 0 Transmembrane 219 zf-C2H2 PF00096.26 RLN73484.1 - 3e-19 68.3 23.4 3e-05 24.2 0.3 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN73484.1 - 4.6e-13 48.8 20.3 0.0078 17.0 0.2 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RLN73484.1 - 3e-11 43.2 29.1 1.3e-07 31.8 0.6 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_8 PF15909.5 RLN73484.1 - 5.7e-05 23.3 13.0 0.031 14.6 1.6 3.4 1 1 0 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 RLN73484.1 - 0.00087 19.5 5.1 10 6.6 0.3 4.4 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 RLN73484.1 - 0.0027 17.9 5.7 10 6.2 0.2 3.8 1 1 3 4 4 4 1 Aberrant zinc-finger zf-C2H2_6 PF13912.6 RLN73484.1 - 0.0068 16.4 12.8 7.8 6.6 0.5 4.8 4 0 0 4 4 4 2 C2H2-type zinc finger FOXP-CC PF16159.5 RLN73484.1 - 0.06 14.0 6.6 1.2 9.9 0.1 3.5 3 1 1 4 4 4 0 FOXP coiled-coil domain zf-met PF12874.7 RLN73484.1 - 0.11 13.0 3.7 4.1 7.9 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf_Hakai PF18408.1 RLN73484.1 - 0.17 11.6 0.0 0.17 11.6 0.0 3.5 4 0 0 4 4 4 0 C2H2 Hakai zinc finger domain TetR_C_20 PF17925.1 RLN73484.1 - 0.18 12.1 0.1 0.32 11.3 0.1 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Ogr_Delta PF04606.12 RLN73484.1 - 0.2 11.7 4.7 1.9 8.6 0.5 3.1 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger CHORD PF04968.12 RLN73484.1 - 0.38 11.5 9.1 14 6.5 0.2 3.5 2 1 1 3 3 3 0 CHORD zf-H2C2_5 PF13909.6 RLN73484.1 - 1.6 8.6 17.4 0.83 9.5 0.1 5.1 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 RLN73484.1 - 2.7 7.8 13.2 4.1 7.2 0.6 4.1 4 0 0 4 4 4 0 zinc-finger C2H2-type Sina PF03145.16 RLN73484.1 - 3.1 7.7 12.2 0.14 12.1 2.7 2.3 1 1 2 3 3 3 0 Seven in absentia protein family Tubulin PF00091.25 RLN73485.1 - 1.7e-57 194.8 0.0 2.8e-57 194.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RLN73485.1 - 9e-26 90.5 0.0 1.7e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 RLN73485.1 - 0.0082 16.4 0.0 0.027 14.8 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain DUF1940 PF09155.10 RLN73485.1 - 0.029 14.5 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) RNA_pol_Rpb1_5 PF04998.17 RLN73486.1 - 1.8e-102 342.4 0.2 3.3e-102 341.5 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 RLN73486.1 - 1.1e-75 253.4 0.3 2.4e-75 252.3 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 RLN73486.1 - 9.1e-65 218.1 1.9 1.7e-64 217.2 1.9 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_1 PF04997.12 RLN73486.1 - 8.7e-58 196.1 0.0 2.3e-57 194.7 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_7 PF04990.12 RLN73486.1 - 3.3e-51 172.8 2.7 6.2e-51 171.9 2.7 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 RLN73486.1 - 2.1e-46 157.7 0.1 6.1e-46 156.2 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_R PF05001.13 RLN73486.1 - 1.6e-44 148.0 366.3 0.0031 17.8 12.5 21.8 6 2 16 29 29 29 26 RNA polymerase Rpb1 C-terminal repeat RNA_pol_Rpb1_4 PF05000.17 RLN73486.1 - 6e-34 116.2 0.0 1.4e-33 115.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Zip PF02535.22 RLN73487.1 - 4e-66 223.5 15.9 1e-65 222.2 10.9 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter UreE_C PF05194.12 RLN73487.1 - 4.5 7.8 25.9 12 6.5 8.9 4.0 4 0 0 4 4 4 0 UreE urease accessory protein, C-terminal domain DnaJ_C PF01556.18 RLN73489.1 - 1.3e-32 112.9 0.0 1.8e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RLN73489.1 - 3e-25 88.1 0.2 5.4e-25 87.3 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 RLN73489.1 - 8.8e-14 51.6 19.9 1.9e-13 50.5 19.9 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 RLN73489.1 - 0.00073 19.5 12.2 0.021 14.8 1.1 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 RLN73489.1 - 0.014 15.1 5.4 0.089 12.4 0.3 2.5 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Lar_restr_allev PF14354.6 RLN73489.1 - 0.17 12.3 19.2 1.3 9.5 0.1 4.7 3 2 1 4 4 4 0 Restriction alleviation protein Lar E7 PF00527.18 RLN73489.1 - 0.17 12.1 3.3 0.19 12.0 0.0 2.7 3 0 0 3 3 3 0 E7 protein, Early protein zf-RING_10 PF16685.5 RLN73489.1 - 0.34 11.1 6.9 0.64 10.2 0.3 2.6 1 1 0 2 2 2 0 zinc RING finger of MSL2 HypA PF01155.19 RLN73489.1 - 0.36 10.9 11.0 2.2 8.3 2.1 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 RLN73489.1 - 6.5 6.8 11.8 0.17 11.9 5.2 1.8 2 0 0 2 2 2 0 zinc-ribbons malic PF00390.19 RLN73490.1 - 3.4e-39 134.5 0.0 4.6e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 RLN73491.1 - 3.9e-92 308.1 0.0 5.1e-92 307.8 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 RLN73491.1 - 1.2e-75 253.4 0.0 1.7e-75 252.8 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Glyco_hydro_43 PF04616.14 RLN73494.1 - 3.3e-14 52.9 0.5 5.3e-14 52.2 0.5 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_43 PF04616.14 RLN73495.1 - 5.5e-37 127.6 1.5 8.4e-37 127.0 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DIOX_N PF14226.6 RLN73498.1 - 7.7e-26 91.2 0.0 1.2e-25 90.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 RLN73498.1 - 8.8e-25 87.1 0.0 2.2e-24 85.8 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily LRR_8 PF13855.6 RLN73499.1 - 1.5e-38 130.4 32.8 4.5e-09 35.9 0.9 7.3 3 3 5 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 RLN73499.1 - 2.6e-28 97.6 22.4 1.6e-05 25.1 0.2 7.9 5 2 3 8 8 8 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN73499.1 - 2.7e-09 36.8 8.5 0.0025 17.4 0.3 4.5 2 2 3 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 RLN73499.1 - 1.3e-06 28.1 29.1 3.6 8.5 0.0 11.9 12 2 0 12 12 12 3 Leucine Rich Repeat LRR_6 PF13516.6 RLN73499.1 - 0.00012 21.9 19.0 2.4 8.4 0.3 8.6 9 0 0 9 9 9 2 Leucine Rich repeat PHD PF00628.29 RLN73502.1 - 0.00012 21.9 6.2 0.00026 20.8 6.2 1.6 1 0 0 1 1 1 1 PHD-finger zf-rbx1 PF12678.7 RLN73502.1 - 0.036 14.4 7.2 0.12 12.6 7.2 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 RLN73502.1 - 0.17 12.3 9.8 0.45 10.9 9.8 1.8 1 0 0 1 1 1 0 Ring finger domain C1_1 PF00130.22 RLN73502.1 - 0.29 11.0 7.3 0.09 12.7 4.2 1.8 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_11 PF17123.5 RLN73502.1 - 1.3 8.8 6.1 3.4 7.5 6.1 1.8 1 0 0 1 1 1 0 RING-like zinc finger SWIM PF04434.17 RLN73503.1 - 1.1e-06 28.1 0.1 1.9e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 SWIM zinc finger MULE PF10551.9 RLN73504.1 - 5.2e-12 46.0 0.0 1.7e-11 44.4 0.0 1.9 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 RLN73504.1 - 0.0029 16.5 0.1 0.0047 15.8 0.1 1.2 1 0 0 1 1 1 1 Transposase, Mutator family ATG16 PF08614.11 RLN73505.1 - 0.059 13.6 9.0 0.088 13.0 9.0 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Snapin_Pallidin PF14712.6 RLN73505.1 - 0.15 12.5 8.3 0.33 11.4 8.3 1.5 1 0 0 1 1 1 0 Snapin/Pallidin DivIC PF04977.15 RLN73505.1 - 1.3 8.8 6.9 0.9 9.3 4.4 2.0 2 0 0 2 2 2 0 Septum formation initiator Filament_head PF04732.14 RLN73505.1 - 1.5 9.8 9.9 0.48 11.3 3.8 2.3 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region ARL2_Bind_BART PF11527.8 RLN73506.1 - 3.2e-06 27.2 0.2 0.0013 18.8 0.0 2.1 1 1 1 2 2 2 2 The ARF-like 2 binding protein BART DUF3692 PF12469.8 RLN73506.1 - 0.054 13.7 0.0 0.074 13.3 0.0 1.4 1 1 0 1 1 1 0 CRISPR-associated protein Cmc1 PF08583.10 RLN73506.1 - 0.11 12.5 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DEAD PF00270.29 RLN73518.1 - 5.4e-50 169.6 0.0 2e-49 167.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN73518.1 - 2e-17 63.6 0.0 1.1e-16 61.1 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain FIST PF08495.10 RLN73518.1 - 2.9e-15 56.7 0.2 9.7e-15 55.0 0.2 2.0 1 0 0 1 1 1 1 FIST N domain FIST_C PF10442.9 RLN73518.1 - 6.2e-08 32.7 0.0 1.7e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 FIST C domain TPR_2 PF07719.17 RLN73522.1 - 0.013 15.6 2.4 0.016 15.3 1.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Paf67 PF10255.9 RLN73522.1 - 0.022 13.8 0.4 0.026 13.5 0.4 1.2 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 TPR_1 PF00515.28 RLN73522.1 - 0.034 14.0 1.1 0.091 12.6 1.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 RLN73522.1 - 0.037 14.3 0.8 0.22 11.8 0.7 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN73522.1 - 0.039 14.2 0.7 0.4 11.0 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Sigma70_r4 PF04545.16 RLN73522.1 - 0.072 12.6 0.2 0.21 11.1 0.1 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 Methyltransf_5 PF01795.19 RLN73531.1 - 1.1e-60 205.7 4.6 7.8e-54 183.3 0.1 2.0 2 0 0 2 2 2 2 MraW methylase family Methyltransf_25 PF13649.6 RLN73531.1 - 0.0063 17.2 0.1 0.019 15.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN73531.1 - 0.0074 16.1 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HHH_3 PF12836.7 RLN73531.1 - 0.065 13.5 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Cwf_Cwc_15 PF04889.12 RLN73531.1 - 9.7 5.8 13.7 27 4.4 13.7 1.6 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ank_2 PF12796.7 RLN73532.1 - 2.6e-26 92.0 11.5 1.2e-07 32.2 0.1 4.1 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) DHHC PF01529.20 RLN73532.1 - 2.8e-25 89.0 1.8 2.8e-25 89.0 1.8 2.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.6 RLN73532.1 - 2.1e-17 63.2 5.0 5.7e-06 26.8 0.1 5.5 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN73532.1 - 1.3e-13 49.8 3.1 0.0086 16.5 0.1 6.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 RLN73532.1 - 5.6e-13 48.8 3.9 2.2e-06 27.8 0.8 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN73532.1 - 6.8e-10 38.9 6.5 0.03 14.8 1.1 6.5 7 0 0 7 7 7 3 Ankyrin repeat Allexi_40kDa PF05549.11 RLN73533.1 - 0.5 9.8 2.6 18 4.7 0.5 2.6 2 0 0 2 2 2 0 Allexivirus 40kDa protein COesterase PF00135.28 RLN73538.1 - 4.6e-90 302.9 0.0 5.8e-90 302.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RLN73538.1 - 9.9e-05 22.3 0.8 0.0013 18.6 0.5 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN73538.1 - 0.059 12.8 0.6 0.11 11.9 0.6 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 RLN73539.1 - 1.7e-93 314.2 0.0 2.2e-93 313.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RLN73539.1 - 9.6e-05 22.3 0.5 0.00077 19.4 0.2 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN73539.1 - 0.001 18.6 0.8 0.0019 17.7 0.8 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Glyco_hydro_3_C PF01915.22 RLN73540.1 - 4.2e-42 144.4 0.1 7.6e-42 143.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 RLN73540.1 - 2.7e-25 89.4 0.0 5.3e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 RLN73540.1 - 1.8e-14 53.6 0.0 3.6e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_transf_20 PF00982.21 RLN73541.1 - 1.2e-134 449.6 0.0 2e-134 448.8 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 RLN73541.1 - 2.5e-44 151.2 0.0 3.6e-40 137.5 0.0 2.4 2 0 0 2 2 2 2 Trehalose-phosphatase Ric8 PF10165.9 RLN73542.1 - 5.7e-07 28.9 2.6 7.3e-07 28.6 2.6 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Mannosyl_trans3 PF11051.8 RLN73547.1 - 3.4e-25 88.9 0.0 4.7e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative Myb_DNA-bind_4 PF13837.6 RLN73548.1 - 9.2e-05 22.8 0.4 0.00018 21.8 0.4 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 RLN73548.1 - 0.00043 20.5 0.4 0.0041 17.4 0.2 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF573 PF04504.14 RLN73548.1 - 0.00063 20.4 1.1 0.0012 19.4 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF573 Myb_DNA-bind_5 PF13873.6 RLN73548.1 - 0.065 13.3 0.2 0.065 13.3 0.2 1.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF3584 PF12128.8 RLN73552.1 - 1.5 6.3 9.7 2.8 5.3 9.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4472 PF14739.6 RLN73552.1 - 5.6 7.7 8.4 0.27 12.0 1.6 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) Tyrosinase PF00264.20 RLN73573.1 - 4.4e-11 43.5 1.1 5.6e-10 39.9 0.2 2.8 2 1 0 2 2 2 1 Common central domain of tyrosinase Tyrosinase PF00264.20 RLN73574.1 - 1.6e-16 61.3 0.3 5.4e-16 59.5 0.3 1.8 1 1 0 1 1 1 1 Common central domain of tyrosinase DUF5363 PF17320.2 RLN73574.1 - 0.059 13.2 0.4 0.059 13.2 0.4 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5363) Amidohydro_1 PF01979.20 RLN73575.1 - 6.2e-72 242.8 0.6 7.7e-72 242.5 0.6 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 RLN73575.1 - 5.9e-20 72.2 3.1 8.6e-18 65.1 0.2 2.4 2 1 0 2 2 2 2 Amidohydrolase family Sial-lect-inser PF09264.10 RLN73576.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Vibrio cholerae sialidase, lectin insertion Tyrosinase PF00264.20 RLN73577.1 - 4.8e-13 49.9 0.1 2e-12 47.9 0.1 1.9 1 1 0 1 1 1 1 Common central domain of tyrosinase RNA_pol_Rpb2_6 PF00562.28 RLN73578.1 - 2e-123 412.3 0.0 2.5e-123 412.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 RLN73578.1 - 1.6e-33 114.9 0.5 4.1e-33 113.6 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 RLN73578.1 - 6.1e-22 77.6 0.2 3.9e-21 75.0 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 RLN73578.1 - 5.4e-20 71.4 2.0 1.1e-19 70.4 2.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.14 RLN73578.1 - 3.4e-10 39.9 0.0 6e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.17 RLN73578.1 - 1.3e-07 32.1 2.8 4.1e-07 30.5 2.8 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_1 PF04563.15 RLN73578.1 - 0.00024 20.7 0.0 0.00035 20.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit HTH_23 PF13384.6 RLN73587.1 - 0.00011 21.8 0.2 0.00025 20.8 0.2 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 RLN73587.1 - 0.00052 20.6 0.0 0.033 14.8 0.0 2.1 1 1 1 2 2 2 2 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 RLN73587.1 - 0.004 16.5 0.8 0.14 11.6 0.1 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 FH2 PF02181.23 RLN73590.1 - 0.022 13.9 0.6 0.044 12.9 0.6 1.4 1 0 0 1 1 1 0 Formin Homology 2 Domain Arnt_C PF18583.1 RLN73590.1 - 0.11 12.1 1.2 0.25 11.0 1.2 1.6 1 0 0 1 1 1 0 Aminoarabinose transferase C-terminal domain DUF5368 PF17336.2 RLN73590.1 - 0.26 11.5 6.6 3.3 7.9 0.3 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5368) ApoLp-III PF07464.11 RLN73590.1 - 0.26 11.4 9.1 0.023 14.8 2.4 2.6 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF2125 PF09898.9 RLN73593.1 - 0.01 15.5 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2125) CnrY PF17524.2 RLN73593.1 - 0.014 15.6 2.1 0.017 15.3 2.1 1.2 1 0 0 1 1 1 0 Anti-sigma factor CnrY TLD PF07534.16 RLN73594.1 - 2.6e-33 115.2 0.1 4e-33 114.6 0.1 1.3 1 0 0 1 1 1 1 TLD NOA36 PF06524.12 RLN73595.1 - 0.23 10.8 14.0 0.46 9.8 14.0 1.4 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.13 RLN73595.1 - 3.6 7.5 18.9 11 5.9 18.9 1.7 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NARP1 PF12569.8 RLN73598.1 - 5.6e-151 504.0 11.6 1.2e-150 502.8 8.5 2.2 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_8 PF13181.6 RLN73598.1 - 7.3e-21 72.6 0.4 4.6e-05 23.3 0.0 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN73598.1 - 7.2e-19 66.3 11.5 4e-05 23.4 0.0 8.2 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 RLN73598.1 - 6.3e-16 57.7 0.7 0.058 14.2 0.1 6.9 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 RLN73598.1 - 7.7e-14 52.0 1.5 0.00099 19.6 0.2 5.7 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN73598.1 - 1.6e-13 49.8 21.7 9.4e-06 25.2 0.1 7.6 9 0 0 9 9 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN73598.1 - 3.3e-12 46.5 5.4 0.00079 19.6 0.1 3.9 3 1 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 RLN73598.1 - 3.6e-12 45.4 7.2 0.0078 16.2 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 RLN73598.1 - 5.5e-12 45.8 5.5 0.026 14.8 0.5 6.5 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 RLN73598.1 - 1.7e-10 41.3 3.0 0.19 12.4 0.0 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN73598.1 - 8.4e-10 38.2 2.9 4e-05 23.2 0.2 3.4 2 0 0 2 2 2 2 TPR repeat Fis1_TPR_C PF14853.6 RLN73598.1 - 1.8e-08 34.3 8.4 0.28 11.3 0.0 5.0 5 0 0 5 5 4 3 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 RLN73598.1 - 4.3e-08 32.7 2.3 0.0089 15.3 1.1 3.2 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN73598.1 - 3e-07 30.5 0.6 1.1 9.5 0.3 5.9 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN73598.1 - 7.7e-07 29.1 2.9 0.47 11.0 0.0 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN73598.1 - 1.4e-05 25.4 6.5 9.3 7.1 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN73598.1 - 0.002 17.9 8.3 1.8 8.6 0.5 5.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_4 PF07721.14 RLN73598.1 - 0.0041 17.6 0.7 56 4.8 0.1 5.3 7 0 0 7 7 6 0 Tetratricopeptide repeat SNAP PF14938.6 RLN73598.1 - 0.03 13.8 0.8 0.87 9.0 0.5 2.9 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP Arm_3 PF16186.5 RLN73598.1 - 0.083 12.5 0.2 0.27 10.8 0.2 1.9 1 0 0 1 1 1 0 Atypical Arm repeat MIT PF04212.18 RLN73598.1 - 0.33 11.1 7.4 2.8 8.1 0.1 4.2 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain E1-E2_ATPase PF00122.20 RLN73601.1 - 5.5e-43 146.6 0.1 1.3e-42 145.3 0.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 RLN73601.1 - 9.5e-37 125.3 13.8 4.6e-09 36.6 0.0 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 RLN73601.1 - 2.3e-17 64.0 0.0 5.4e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FeS_assembly_P PF01883.19 RLN73601.1 - 0.11 12.7 0.1 0.11 12.7 0.1 4.5 5 0 0 5 5 5 0 Iron-sulfur cluster assembly protein DUF1700 PF08006.11 RLN73601.1 - 0.19 11.3 4.7 0.03 13.9 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) DUF2997 PF11211.8 RLN73601.1 - 1.2 9.0 5.8 0.25 11.1 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2997) Fer2_BFD PF04324.15 RLN73601.1 - 3 8.3 11.0 15 6.0 0.0 4.3 4 1 0 4 4 4 0 BFD-like [2Fe-2S] binding domain Nucleoporin_N PF08801.11 RLN73609.1 - 3.5e-50 171.0 0.0 2.1e-49 168.5 0.0 2.0 1 1 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 RLN73609.1 - 5e-07 28.8 1.4 9.1e-07 28.0 1.4 1.3 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal ArfGap PF01412.18 RLN73610.1 - 3.5e-25 88.3 0.0 6e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf C2 PF00168.30 RLN73610.1 - 4.2e-14 52.7 0.0 7.6e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain ATG_C PF09333.11 RLN73610.1 - 0.0059 16.9 0.0 0.015 15.6 0.0 1.6 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain EF-hand_7 PF13499.6 RLN73610.1 - 0.074 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair DUF1713 PF08213.11 RLN73611.1 - 7.2e-08 32.2 19.1 1.1e-07 31.7 19.1 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) B9-C2 PF07162.11 RLN73612.1 - 6e-45 153.5 0.1 8.5e-45 153.0 0.1 1.2 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DDE_1 PF03184.19 RLN73613.1 - 1.3e-17 64.0 0.0 4.6e-12 45.9 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN73613.1 - 2.8e-11 43.3 0.1 5.9e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 RLN73613.1 - 0.0011 18.6 0.1 0.0022 17.6 0.1 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_32 PF13565.6 RLN73613.1 - 0.0018 18.9 0.3 1.2 9.8 0.0 3.0 1 1 1 2 2 2 2 Homeodomain-like domain UPF0020 PF01170.18 RLN73614.1 - 4.2e-15 56.0 0.0 8.2e-14 51.8 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 THUMP PF02926.17 RLN73614.1 - 3.9e-07 30.3 0.1 8.4e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 THUMP domain Methyltransf_25 PF13649.6 RLN73614.1 - 0.0013 19.4 0.0 0.0029 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN73614.1 - 0.0026 17.1 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 RLN73614.1 - 0.0031 18.1 0.0 0.007 17.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DUF429 PF04250.13 RLN73614.1 - 0.081 12.7 0.1 0.19 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF429) Nup88 PF10168.9 RLN73615.1 - 0.0049 14.8 3.7 0.0074 14.2 3.7 1.1 1 0 0 1 1 1 1 Nuclear pore component PDZ_6 PF17820.1 RLN73615.1 - 0.0078 16.0 0.1 0.022 14.6 0.1 1.8 1 0 0 1 1 1 1 PDZ domain BH3 PF15285.6 RLN73615.1 - 0.058 13.2 0.0 0.18 11.6 0.0 1.9 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting Sec6 PF06046.13 RLN73616.1 - 0.32 9.3 0.1 0.47 8.8 0.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 FHA PF00498.26 RLN73617.1 - 1.1e-08 35.3 0.1 2.1e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 FHA domain AAA_16 PF13191.6 RLN73617.1 - 0.00071 20.0 0.0 0.0026 18.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 RLN73617.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Beta-Casp PF10996.8 RLN73618.1 - 1.3e-31 109.1 0.0 2.7e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 RLN73618.1 - 5.2e-22 78.2 0.0 1.1e-21 77.2 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 RLN73618.1 - 7.6e-21 75.0 0.6 1.4e-20 74.2 0.3 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 RLN73618.1 - 1.8e-17 63.0 0.0 3.8e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 RLN73618.1 - 4e-10 39.6 0.2 8.7e-10 38.5 0.2 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 RLN73618.1 - 4.1e-06 26.8 0.1 1.8e-05 24.7 0.1 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 RLN73618.1 - 5.5e-06 25.8 0.0 9.9e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Putative beta-lactamase-like family Baculo_RING PF05883.11 RLN73620.1 - 0.12 12.4 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-C3HC4_3 PF13920.6 RLN73621.1 - 6.7e-07 29.1 5.9 1.2e-06 28.3 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN73621.1 - 0.0001 22.0 5.3 0.00018 21.3 5.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 PKD_channel PF08016.12 RLN73627.1 - 5.5e-22 78.0 23.1 7.2e-19 67.8 12.0 3.8 3 1 1 4 4 4 3 Polycystin cation channel Ion_trans PF00520.31 RLN73627.1 - 7e-11 41.8 9.4 1.3e-10 40.9 9.4 1.4 1 0 0 1 1 1 1 Ion transport protein LPD24 PF18839.1 RLN73627.1 - 0.045 14.0 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 Large polyvalent protein associated domain 24 ABC_tran PF00005.27 RLN73628.1 - 7.4e-18 65.4 0.0 1.3e-17 64.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN73628.1 - 8e-07 29.2 3.4 0.0051 16.7 0.9 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RLN73628.1 - 5.8e-06 25.9 0.9 3.4e-05 23.4 0.9 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SRP54 PF00448.22 RLN73628.1 - 5.5e-05 22.9 0.1 8.9e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 RLN73628.1 - 0.0003 20.1 0.1 0.00047 19.5 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 RLN73628.1 - 0.0013 18.5 0.6 0.005 16.6 0.6 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 RLN73628.1 - 0.0019 18.1 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN73628.1 - 0.0021 17.8 0.2 0.0044 16.7 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN73628.1 - 0.0024 18.3 0.7 0.0045 17.4 0.7 1.5 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 RLN73628.1 - 0.0031 17.6 0.1 0.0065 16.5 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 RLN73628.1 - 0.004 16.9 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.23 RLN73628.1 - 0.0064 16.6 0.1 0.01 15.9 0.1 1.3 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 RLN73628.1 - 0.007 16.6 0.2 0.021 15.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 RLN73628.1 - 0.016 15.7 0.2 0.021 15.3 0.2 1.5 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 RLN73628.1 - 0.05 12.9 0.0 0.091 12.0 0.0 1.4 1 0 0 1 1 1 0 Septin T2SSE PF00437.20 RLN73628.1 - 0.065 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 RLN73628.1 - 0.081 13.1 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 RLN73628.1 - 0.11 11.8 0.1 0.22 10.8 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family PduV-EutP PF10662.9 RLN73628.1 - 0.2 11.4 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 RLN73628.1 - 0.23 11.7 1.2 1.4 9.2 1.2 2.1 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 RLN73628.1 - 0.37 10.5 2.6 3.3 7.4 0.3 2.3 1 1 0 2 2 2 0 IstB-like ATP binding protein Pkinase PF00069.25 RLN73629.1 - 7.6e-38 130.4 0.2 3.4e-28 98.8 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN73629.1 - 9.9e-19 67.6 0.1 4.7e-12 45.7 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase NAF PF03822.14 RLN73629.1 - 5e-09 36.2 0.1 1.2e-08 34.9 0.1 1.7 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.6 RLN73629.1 - 0.022 14.1 0.0 0.053 12.8 0.0 1.7 1 1 0 1 1 1 0 Kinase-like KA1 PF02149.19 RLN73629.1 - 0.03 14.1 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 Kinase associated domain 1 cobW PF02492.19 RLN73630.1 - 1.5e-50 171.2 0.0 3.1e-50 170.2 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 RLN73630.1 - 3.7e-14 52.4 0.0 8.2e-14 51.3 0.0 1.7 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain TsaE PF02367.17 RLN73630.1 - 0.0051 16.8 0.2 0.017 15.1 0.1 1.9 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 RLN73630.1 - 0.055 13.9 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 RLN73630.1 - 0.064 13.1 0.1 2.1 8.2 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Flavi_NS2B PF01002.19 RLN73630.1 - 0.075 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B RsgA_GTPase PF03193.16 RLN73630.1 - 0.075 12.9 0.0 4.2 7.2 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Pribosyltran_N PF13793.6 RLN73631.1 - 7.5e-24 83.9 0.7 7.7e-23 80.6 0.4 2.5 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 RLN73631.1 - 3.8e-18 66.2 0.6 8e-18 65.1 0.6 1.6 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 RLN73631.1 - 4e-12 45.9 0.6 3.7e-11 42.8 0.1 2.4 2 1 1 3 3 3 1 Phosphoribosyl transferase domain SPA PF08616.10 RLN73631.1 - 0.066 13.2 0.6 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 Stabilization of polarity axis DUF846 PF05832.12 RLN73632.1 - 1.2e-51 174.4 11.8 3e-51 173.1 11.8 1.6 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Wzz PF02706.15 RLN73633.1 - 1.4 9.3 3.8 24 5.3 0.7 2.5 2 0 0 2 2 2 0 Chain length determinant protein PKD_channel PF08016.12 RLN73634.1 - 2.4e-36 125.3 21.9 1.1e-30 106.8 19.3 3.0 1 1 1 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 RLN73634.1 - 2.3e-09 36.9 18.6 8.9e-09 34.9 18.6 2.0 1 1 0 1 1 1 1 Ion transport protein FeoB_associated PF12669.7 RLN73634.1 - 2.2 8.8 0.0 2.2 8.8 0.0 3.4 4 0 0 4 4 4 0 FeoB-associated Cys-rich membrane protein cNMP_binding PF00027.29 RLN73635.1 - 1.2e-46 156.7 1.0 2.2e-12 46.8 0.0 5.7 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN73635.1 - 1.3e-26 93.4 40.2 2.2e-11 43.5 9.4 4.5 4 0 0 4 4 4 4 Ion transport protein Ion_trans_2 PF07885.16 RLN73635.1 - 1.3 9.1 16.5 0.087 12.8 0.3 4.6 4 0 0 4 4 4 0 Ion channel CLASP_N PF12348.8 RLN73636.1 - 0.00019 21.1 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 CLASP N terminal WD40 PF00400.32 RLN73637.1 - 4.5e-23 81.1 15.9 2.2e-05 25.1 0.4 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN73637.1 - 4.9e-09 36.4 6.2 3e-05 24.2 1.0 3.7 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN73637.1 - 3.4e-06 26.3 0.2 0.047 12.6 0.0 3.6 3 1 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WDCP PF15390.6 RLN73637.1 - 0.036 12.5 0.1 0.051 12.0 0.1 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family TPR_2 PF07719.17 RLN73639.1 - 0.34 11.2 3.8 7.9 6.9 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4483 PF14825.6 RLN73640.1 - 9.4e-07 28.7 0.1 0.061 13.1 0.0 3.8 2 1 2 4 4 4 2 Domain of unknown function (DUF4483) Myb_DNA-binding PF00249.31 RLN73644.1 - 6.8e-12 45.4 0.1 1.1e-11 44.7 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN73644.1 - 0.0085 16.3 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Nkap_C PF06047.11 RLN73647.1 - 6.1e-21 74.4 3.8 7.7e-21 74.1 3.8 1.1 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain PHO4 PF01384.20 RLN73653.1 - 1.6e-97 326.6 27.9 2.2e-97 326.1 27.9 1.2 1 0 0 1 1 1 1 Phosphate transporter family FAD_binding_8 PF08022.12 RLN73658.1 - 2.3e-20 72.7 0.0 4.8e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 RLN73658.1 - 2.9e-19 69.4 3.9 6.7e-19 68.2 3.9 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 RLN73658.1 - 3.3e-14 53.3 0.0 2.8e-13 50.3 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 RLN73658.1 - 0.0018 18.9 0.0 0.45 11.2 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 RLN73659.1 - 2e-19 69.7 0.0 3.7e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 RLN73659.1 - 2.5e-18 66.4 5.8 9e-18 64.6 5.8 2.0 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 RLN73659.1 - 3.4e-16 59.7 0.0 7.1e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 RLN73659.1 - 0.00012 22.7 0.0 0.69 10.6 0.0 2.6 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 RLN73659.1 - 0.066 13.6 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain TssN PF17555.2 RLN73659.1 - 0.28 10.5 6.1 0.42 9.9 6.1 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN Ni_hydr_CYTB PF01292.20 RLN73659.1 - 1.6 8.3 11.3 3.1 7.4 11.3 1.5 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 FAD_binding_8 PF08022.12 RLN73660.1 - 2.5e-20 72.6 0.0 6.6e-20 71.2 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 RLN73660.1 - 2.1e-17 63.4 9.7 2.1e-17 63.4 9.7 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 RLN73660.1 - 1e-12 48.4 0.0 6.8e-12 45.8 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 RLN73660.1 - 6.1e-05 23.6 0.0 0.35 11.5 0.0 2.9 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 RLN73660.1 - 0.018 15.4 0.0 0.037 14.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF2304 PF10066.9 RLN73660.1 - 4.5 7.5 11.5 1 9.6 7.8 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) CBAH PF02275.18 RLN73661.1 - 3.4e-24 86.1 0.0 7.7e-24 84.9 0.0 1.6 1 1 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family OrfB_Zn_ribbon PF07282.11 RLN73662.1 - 2.9e-10 39.9 0.0 5.7e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HTH_OrfB_IS605 PF12323.8 RLN73662.1 - 1.9e-09 36.9 1.8 4.7e-09 35.6 1.8 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain FAD_binding_8 PF08022.12 RLN73663.1 - 8.6e-20 70.9 0.0 5.2e-19 68.3 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 RLN73663.1 - 5.3e-18 65.3 13.2 5.3e-18 65.3 13.2 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 RLN73663.1 - 1.2e-12 48.2 0.0 2.3e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 RLN73663.1 - 0.00032 21.3 0.0 0.38 11.4 0.0 3.1 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain Metallophos PF00149.28 RLN73664.1 - 7.3e-14 52.7 0.2 1.7e-13 51.6 0.1 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RLN73664.1 - 0.0033 17.6 0.0 0.033 14.4 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain SH3_7 PF12914.7 RLN73664.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 SH3 domain of SH3b2 type FAD_binding_8 PF08022.12 RLN73665.1 - 7.6e-19 67.8 0.0 1.6e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 RLN73665.1 - 1.4e-17 64.0 7.8 3.8e-17 62.6 7.8 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 RLN73665.1 - 1.5e-08 34.9 0.0 5.5e-08 33.1 0.0 2.0 2 1 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 RLN73665.1 - 0.0021 18.7 0.0 1.2 9.8 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 RLN73665.1 - 0.0039 17.5 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain TIC20 PF16166.5 RLN73665.1 - 0.017 14.9 1.6 0.04 13.7 1.6 1.6 1 0 0 1 1 1 0 Chloroplast import apparatus Tic20-like Gram_pos_anchor PF00746.21 RLN73665.1 - 0.095 12.7 4.3 0.11 12.4 0.3 2.8 3 0 0 3 3 3 0 LPXTG cell wall anchor motif Cyt_bd_oxida_II PF02322.15 RLN73665.1 - 0.12 11.7 10.7 0.15 11.4 9.7 1.5 1 1 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II GWT1 PF06423.12 RLN73665.1 - 0.18 11.9 0.6 0.31 11.2 0.6 1.3 1 0 0 1 1 1 0 GWT1 FAD_binding_8 PF08022.12 RLN73666.1 - 7e-42 141.9 0.0 3.2e-20 72.2 0.0 2.8 3 0 0 3 3 3 2 FAD-binding domain Ferric_reduct PF01794.19 RLN73666.1 - 1.7e-31 108.9 32.1 4e-17 62.5 13.3 2.6 2 0 0 2 2 2 2 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 RLN73666.1 - 2.4e-12 47.3 0.0 0.00035 20.7 0.0 3.5 3 0 0 3 3 3 3 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 RLN73666.1 - 1.5e-05 25.2 0.0 0.25 11.7 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 RLN73666.1 - 0.0037 17.9 0.0 16 6.2 0.0 3.7 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 RLN73667.1 - 9.9e-19 67.4 0.0 2e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 RLN73667.1 - 3.3e-10 40.3 0.0 1.2e-08 35.2 0.0 2.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 RLN73667.1 - 0.00012 22.1 13.6 0.00039 20.5 13.6 1.8 1 1 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 RLN73667.1 - 0.0026 18.4 0.0 1.7 9.3 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 RLN73667.1 - 0.18 12.2 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Peptidase_U4 PF03419.13 RLN73667.1 - 1.1 8.5 8.5 1.7 7.9 8.5 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA STIMATE PF12400.8 RLN73672.1 - 5.5e-35 120.6 2.7 9.4e-35 119.9 2.7 1.4 1 0 0 1 1 1 1 STIMATE family Pkinase_Tyr PF07714.17 RLN73673.1 - 3e-13 49.7 0.0 2e-12 47.0 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 RLN73673.1 - 0.052 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CrgA PF06781.12 RLN73674.1 - 0.027 14.5 0.0 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 Cell division protein CrgA RNase_PH PF01138.21 RLN73675.1 - 3e-22 79.5 0.4 4.8e-22 78.9 0.4 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RLN73675.1 - 4e-09 36.4 0.0 1.4e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Ank_2 PF12796.7 RLN73682.1 - 2.1e-28 98.7 6.7 1.4e-09 38.4 2.4 4.8 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN73682.1 - 4.1e-20 71.9 9.8 9.4e-05 22.9 0.0 6.7 2 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN73682.1 - 2.9e-19 68.9 15.3 1.4e-05 25.2 1.1 6.3 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN73682.1 - 3.6e-17 60.7 9.9 0.016 15.7 0.0 8.6 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 RLN73682.1 - 3.8e-17 61.9 16.0 0.00022 21.5 0.2 8.0 7 0 0 7 7 7 4 Ankyrin repeat zf-TAZ PF02135.16 RLN73683.1 - 1e-07 32.3 18.0 1.9e-07 31.5 18.0 1.4 1 0 0 1 1 1 1 TAZ zinc finger DUF3987 PF13148.6 RLN73683.1 - 0.0018 17.4 0.1 0.0027 16.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) DNA_ligase_A_C PF04679.15 RLN73684.1 - 3.7e-25 88.4 0.0 6.9e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_A_M PF01068.21 RLN73684.1 - 9.4e-10 38.5 0.1 1.6e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.6 RLN73684.1 - 0.015 15.3 0.4 7.6 6.6 0.2 2.3 2 0 0 2 2 2 0 DNA ligase OB-like domain MHC_II_beta PF00969.19 RLN73684.1 - 0.031 14.4 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain Dynein_light PF01221.18 RLN73685.1 - 3e-15 56.3 0.2 5.3e-15 55.5 0.2 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.18 RLN73685.1 - 0.03 15.0 0.2 0.16 12.7 0.2 2.0 1 1 0 1 1 1 0 Ground-like domain DUF4854 PF16146.5 RLN73685.1 - 0.031 14.6 0.2 0.044 14.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4854) Peptidase_S49_N PF08496.10 RLN73685.1 - 0.065 13.3 1.0 0.092 12.8 1.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SH3_14 PF18343.1 RLN73685.1 - 0.086 12.9 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Dda helicase SH3 domain THF_DHG_CYH_C PF02882.19 RLN73687.1 - 4.3e-64 214.7 0.5 9.5e-64 213.5 0.5 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 RLN73687.1 - 2.5e-32 111.6 0.0 3.7e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Haem_degrading PF03928.14 RLN73687.1 - 0.041 13.9 0.8 0.33 11.0 0.3 2.2 2 0 0 2 2 2 0 Haem-degrading AlaDh_PNT_C PF01262.21 RLN73687.1 - 0.076 12.3 1.4 0.58 9.4 0.4 2.3 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3522 PF12036.8 RLN73688.1 - 4.7e-25 89.0 1.4 5.6e-25 88.7 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) ADIP PF11559.8 RLN73689.1 - 0.0035 17.4 5.7 0.0047 17.0 5.7 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF2780 PF11075.8 RLN73689.1 - 0.011 15.9 3.1 0.012 15.8 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function VcgC/VcgE (DUF2780) SPATA24 PF15175.6 RLN73689.1 - 0.013 15.4 2.2 0.016 15.1 2.2 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 DUF3584 PF12128.8 RLN73689.1 - 0.02 12.4 7.3 0.023 12.3 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PKcGMP_CC PF16808.5 RLN73689.1 - 0.027 14.3 0.5 0.072 12.9 0.5 1.8 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Golgin_A5 PF09787.9 RLN73689.1 - 0.029 13.8 5.3 0.035 13.6 5.3 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 Spc7 PF08317.11 RLN73689.1 - 0.034 13.0 5.7 0.041 12.8 5.7 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein NYD-SP28 PF14772.6 RLN73689.1 - 0.2 11.7 7.5 0.27 11.3 7.5 1.2 1 0 0 1 1 1 0 Sperm tail DUF641 PF04859.12 RLN73689.1 - 0.22 11.9 4.5 0.57 10.5 4.5 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) ZapB PF06005.12 RLN73689.1 - 0.31 11.5 9.8 0.59 10.6 9.8 1.7 1 1 0 1 1 1 0 Cell division protein ZapB Atg14 PF10186.9 RLN73689.1 - 0.4 9.7 7.4 0.48 9.5 7.4 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 RLN73689.1 - 0.58 9.5 7.3 1.8 7.9 7.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-H PF05837.12 RLN73689.1 - 1.1 9.7 7.9 1.4 9.3 7.9 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DivIC PF04977.15 RLN73689.1 - 1.2 8.9 5.5 1.7 8.5 3.2 2.1 1 1 1 2 2 2 0 Septum formation initiator CHD5 PF04420.14 RLN73689.1 - 1.5 8.6 3.4 2 8.3 3.4 1.3 1 1 0 1 1 1 0 CHD5-like protein OmpH PF03938.14 RLN73689.1 - 2.5 8.5 9.0 2.6 8.4 0.8 1.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) HSCB_C PF07743.13 RLN73689.1 - 3.1 8.3 8.2 11 6.5 5.2 2.2 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain CS PF04969.16 RLN73690.1 - 0.035 15.1 0.1 0.078 14.0 0.1 1.6 1 1 0 1 1 1 0 CS domain SGS PF05002.15 RLN73690.1 - 0.066 13.3 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 SGS domain eIF-5a PF01287.20 RLN73691.1 - 6.1e-05 23.0 0.1 0.00013 22.0 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold MULE PF10551.9 RLN73692.1 - 3.4e-05 24.2 0.1 6.9e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain MULE PF10551.9 RLN73693.1 - 1.1e-09 38.6 0.0 1.7e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 MULE transposase domain DUF3018 PF11455.8 RLN73693.1 - 0.063 13.2 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3018) Alpha_kinase PF02816.18 RLN73694.1 - 6e-46 156.9 0.7 9.5e-46 156.2 0.7 1.3 1 0 0 1 1 1 1 Alpha-kinase family zf-CCCH PF00642.24 RLN73694.1 - 6e-12 45.2 20.0 0.00017 21.4 1.6 3.7 2 1 1 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 RLN73694.1 - 1.7e-08 35.1 9.3 0.024 15.3 0.0 3.6 2 1 1 3 3 3 3 Torus domain zf_CCCH_4 PF18345.1 RLN73694.1 - 2e-06 27.6 28.0 0.028 14.5 2.1 3.8 3 0 0 3 3 3 3 Zinc finger domain VWA_2 PF13519.6 RLN73694.1 - 6.7e-06 26.7 0.0 1.5e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-CCCH_4 PF18044.1 RLN73694.1 - 5.9e-05 22.8 22.4 0.097 12.5 2.2 3.8 3 0 0 3 3 3 3 CCCH-type zinc finger Methyltransf_16 PF10294.9 RLN73694.1 - 0.08 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Lysine methyltransferase tRNA-synt_1e PF01406.19 RLN73703.1 - 7.8e-107 357.1 0.0 1.6e-106 356.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 RLN73703.1 - 1.1e-12 47.4 0.1 1.3e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 RLN73703.1 - 8e-05 21.1 0.0 0.0071 14.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 RLN73703.1 - 0.0005 20.5 0.2 0.002 18.5 0.2 2.1 1 0 0 1 1 1 1 DALR domain tRNA-synt_1c PF00749.21 RLN73703.1 - 0.03 13.2 0.1 0.071 12.0 0.1 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain DUF4241 PF14025.6 RLN73703.1 - 0.037 14.3 0.3 0.093 13.0 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) Pyridox_ox_2 PF12900.7 RLN73703.1 - 0.12 12.4 0.2 0.74 9.8 0.2 2.5 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase GPHH PF16905.5 RLN73703.1 - 0.15 11.8 0.0 0.47 10.3 0.0 1.8 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated RNase_J_C PF17770.1 RLN73704.1 - 0.056 14.5 2.9 0.1 13.7 1.9 1.9 1 1 1 2 2 2 0 Ribonuclease J C-terminal domain Anoctamin PF04547.12 RLN73706.1 - 6.5e-49 167.0 3.2 8.3e-49 166.6 3.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel EF-hand_6 PF13405.6 RLN73706.1 - 1.2e-06 27.9 0.0 0.00085 19.1 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RLN73706.1 - 4.5e-05 22.7 0.0 0.033 13.7 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RLN73706.1 - 0.00033 21.1 0.0 0.00075 19.9 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RLN73706.1 - 0.001 18.9 0.0 0.04 13.8 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN73706.1 - 0.11 12.0 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 EF hand RSN1_7TM PF02714.15 RLN73706.1 - 0.54 9.5 9.3 0.039 13.3 1.9 2.6 1 1 1 3 3 3 0 Calcium-dependent channel, 7TM region, putative phosphate MFS_1 PF07690.16 RLN73706.1 - 5.8 5.7 11.2 0.21 10.5 4.3 1.9 2 0 0 2 2 2 0 Major Facilitator Superfamily DUF5071 PF16804.5 RLN73707.1 - 0.13 12.6 0.0 0.54 10.5 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5071) HEAT PF02985.22 RLN73707.1 - 0.29 11.5 7.4 18 5.9 0.2 4.7 4 0 0 4 4 4 0 HEAT repeat EF-hand_1 PF00036.32 RLN73708.1 - 2.8e-13 48.4 0.6 2.7e-06 26.5 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN73708.1 - 3.3e-12 45.3 0.1 0.00014 21.5 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RLN73708.1 - 7.4e-12 44.2 0.6 4e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RLN73708.1 - 5.5e-11 42.8 0.6 1.4e-10 41.4 0.6 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RLN73708.1 - 3.2e-07 30.1 0.6 0.0064 16.3 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RLN73708.1 - 0.046 14.0 0.1 0.13 12.6 0.1 1.8 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region zf-C3HC4_3 PF13920.6 RLN73709.1 - 8.5e-05 22.3 10.8 8.5e-05 22.3 10.8 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.6 RLN73709.1 - 0.022 15.6 0.2 0.022 15.6 0.2 6.4 6 1 0 6 6 6 0 C2H2-type zinc finger zf-C2H2 PF00096.26 RLN73709.1 - 0.1 13.1 0.2 0.1 13.1 0.2 5.4 5 0 0 5 5 5 0 Zinc finger, C2H2 type SpoU_methylase PF00588.19 RLN73710.1 - 2.8e-07 30.8 0.0 4.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 RLN73710.1 - 3.1e-06 27.4 0.1 9e-06 25.9 0.1 1.7 1 1 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding HupE_UreJ PF04955.12 RLN73711.1 - 0.015 14.8 4.9 0.015 14.8 4.9 2.7 2 2 0 3 3 3 0 HupE / UreJ protein APC_u9 PF16633.5 RLN73711.1 - 0.021 15.9 0.3 0.021 15.9 0.3 1.9 2 0 0 2 2 2 0 Unstructured region on APC between 1st two creatine-rich regions MerE PF05052.12 RLN73711.1 - 0.03 14.2 2.6 0.03 14.2 2.6 1.9 2 0 0 2 2 2 0 MerE protein DUF4307 PF14155.6 RLN73711.1 - 0.052 13.4 0.2 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) HupE_UreJ_2 PF13795.6 RLN73711.1 - 0.098 12.3 3.0 0.57 9.8 0.5 2.4 2 1 0 2 2 2 0 HupE / UreJ protein CrgA PF06781.12 RLN73711.1 - 8.6 6.5 5.8 11 6.2 2.1 2.8 2 0 0 2 2 2 0 Cell division protein CrgA WH2 PF02205.20 RLN73712.1 - 1.7e-10 40.4 12.7 4.7e-08 32.6 1.0 3.0 3 0 0 3 3 3 2 WH2 motif WW PF00397.26 RLN73712.1 - 0.00012 22.1 2.1 0.00021 21.3 2.1 1.4 1 0 0 1 1 1 1 WW domain SNase PF00565.17 RLN73714.1 - 2.6e-33 114.7 0.1 3.6e-13 49.9 0.0 3.4 3 0 0 3 3 3 3 Staphylococcal nuclease homologue AAA_25 PF13481.6 RLN73719.1 - 0.11 12.1 0.1 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Ras PF00071.22 RLN73719.1 - 0.13 11.9 0.1 0.98 9.0 0.0 2.1 2 0 0 2 2 2 0 Ras family CbiA PF01656.23 RLN73719.1 - 0.14 12.2 0.0 0.39 10.8 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_10 PF12846.7 RLN73719.1 - 0.22 10.4 0.0 0.37 9.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Pkinase PF00069.25 RLN73724.1 - 4.3e-72 242.6 0.0 5.5e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN73724.1 - 1.4e-33 116.3 0.0 2e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN73724.1 - 0.037 13.4 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN73724.1 - 0.09 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 RLN73724.1 - 0.11 12.4 0.0 1.6 8.6 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Acyl-CoA_ox_N PF14749.6 RLN73726.1 - 1e-10 42.2 0.3 1.1e-10 42.1 0.3 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal DUF1754 PF08555.10 RLN73727.1 - 9.4e-06 26.3 21.6 0.00011 22.9 21.6 2.1 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) FAM60A PF15396.6 RLN73727.1 - 0.62 10.0 9.3 0.69 9.9 9.3 1.0 1 0 0 1 1 1 0 Protein Family FAM60A PPL5 PF18168.1 RLN73727.1 - 1.5 8.0 6.5 1.7 7.9 6.5 1.0 1 0 0 1 1 1 0 Prim-pol family 5 ALGX PF16822.5 RLN73731.1 - 0.044 13.5 0.0 0.075 12.7 0.0 1.4 1 1 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX bZIP_Maf PF03131.17 RLN73731.1 - 0.35 11.4 4.3 0.16 12.5 1.4 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor Band_3_cyto PF07565.13 RLN73732.1 - 2.8 7.7 5.6 2.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF848 PF05852.11 RLN73733.1 - 0.0029 17.7 0.0 0.0042 17.2 0.0 1.3 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) PapD_N PF00345.20 RLN73734.1 - 0.024 14.5 0.1 0.067 13.1 0.1 1.7 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain OGG_N PF07934.12 RLN73734.1 - 0.075 13.1 1.0 0.19 11.8 1.0 1.7 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain bZIP_2 PF07716.15 RLN73734.1 - 0.37 10.9 3.9 1.2 9.2 0.1 3.0 2 0 0 2 2 2 0 Basic region leucine zipper Rab5ip PF07019.12 RLN73741.1 - 0.066 13.8 0.4 0.066 13.8 0.4 2.4 3 1 0 3 3 3 0 Rab5-interacting protein (Rab5ip) RE_EcoO109I PF14511.6 RLN73741.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease EcoO109I LRR_4 PF12799.7 RLN73743.1 - 0.065 13.7 2.4 6.4 7.4 0.3 2.8 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Pkinase PF00069.25 RLN73744.1 - 8.7e-50 169.5 0.0 1.2e-49 169.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN73744.1 - 1.4e-40 139.2 0.0 1.8e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN73744.1 - 0.0035 17.3 0.1 1.9 8.4 0.0 2.7 1 1 1 3 3 3 2 Phosphotransferase enzyme family GT87 PF09594.10 RLN73744.1 - 0.054 13.2 0.2 0.097 12.4 0.2 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 87 DUF347 PF03988.12 RLN73744.1 - 0.082 13.1 0.6 0.24 11.6 0.1 2.0 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Pkinase PF00069.25 RLN73745.1 - 1.2e-30 106.8 0.0 1.5e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN73745.1 - 9.7e-28 97.1 0.0 1.3e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase SP_C-Propep PF08999.10 RLN73745.1 - 0.026 14.3 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Pkinase_fungal PF17667.1 RLN73745.1 - 0.036 12.8 0.0 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Insulin_TMD PF17870.1 RLN73745.1 - 0.036 14.1 1.0 0.064 13.3 1.0 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment APH PF01636.23 RLN73745.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4448 PF14610.6 RLN73745.1 - 0.075 12.8 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DAG1 PF05454.11 RLN73745.1 - 0.11 11.9 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) TMEM154 PF15102.6 RLN73745.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Myosin_head PF00063.21 RLN73751.1 - 2.1e-232 773.2 0.0 2.6e-232 772.8 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 RLN73751.1 - 8.8e-20 71.2 0.0 9.8e-15 54.7 0.0 2.6 2 0 0 2 2 2 2 Unconventional myosin tail, actin- and lipid-binding FYVE PF01363.21 RLN73751.1 - 1.1e-10 41.5 0.0 2.4e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger DUF1682 PF07946.14 RLN73751.1 - 0.00091 18.5 10.1 0.00091 18.5 10.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1682) Hpr_kinase_C PF07475.12 RLN73751.1 - 0.0012 18.4 0.0 0.36 10.3 0.0 3.0 3 0 0 3 3 3 2 HPr Serine kinase C-terminal domain RsgA_GTPase PF03193.16 RLN73751.1 - 0.023 14.6 0.1 0.057 13.3 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 RLN73751.1 - 0.16 12.4 0.8 0.44 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain LRR_4 PF12799.7 RLN73752.1 - 8.7e-31 105.5 38.5 0.00017 21.9 0.5 11.4 5 2 2 11 11 11 9 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RLN73752.1 - 4.6e-30 101.1 59.0 0.036 14.1 0.2 18.7 19 1 0 19 19 19 11 Leucine Rich repeat LRR_8 PF13855.6 RLN73752.1 - 3.1e-13 49.3 33.9 0.0002 21.0 0.1 9.1 3 2 7 11 11 11 7 Leucine rich repeat LRR_5 PF13306.6 RLN73752.1 - 7.4e-07 29.2 2.1 0.15 12.0 0.0 4.9 2 1 4 6 6 6 4 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 RLN73752.1 - 0.00094 19.4 39.1 32 5.6 0.1 14.9 17 2 0 17 17 17 0 Leucine Rich Repeat DHFR_2 PF06442.11 RLN73752.1 - 0.018 14.9 0.1 17 5.4 0.0 3.5 3 0 0 3 3 3 0 R67 dihydrofolate reductase SAM_Ste50p PF09235.10 RLN73752.1 - 0.041 14.1 12.8 51 4.2 0.0 6.7 5 2 2 7 7 7 0 Ste50p, sterile alpha motif Phasin_2 PF09361.10 RLN73752.1 - 0.28 11.5 3.4 23 5.3 0.0 4.9 6 0 0 6 6 6 0 Phasin protein eIF-6 PF01912.18 RLN73753.1 - 6.6e-81 270.4 1.3 9.2e-81 269.9 0.6 1.5 2 0 0 2 2 2 1 eIF-6 family DUF2570 PF10828.8 RLN73754.1 - 0.00053 19.8 7.8 0.00053 19.8 7.8 5.8 4 1 1 5 5 5 1 Protein of unknown function (DUF2570) DUF4157 PF13699.6 RLN73755.1 - 0.039 14.2 0.6 0.055 13.7 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) CD20 PF04103.15 RLN73755.1 - 0.079 13.0 0.2 0.1 12.7 0.2 1.1 1 0 0 1 1 1 0 CD20-like family SR-25 PF10500.9 RLN73755.1 - 0.13 11.8 13.4 0.15 11.6 13.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 RLN73755.1 - 2 6.6 14.3 2.4 6.4 14.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Acyl-CoA_dh_2 PF08028.11 RLN73762.1 - 0.02 15.2 1.1 0.021 15.1 0.4 1.4 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Vmethyltransf_C PF08456.10 RLN73762.1 - 0.055 13.0 0.2 0.063 12.9 0.2 1.1 1 0 0 1 1 1 0 Viral methyltransferase C-terminal PseudoU_synth_2 PF00849.22 RLN73764.1 - 6.9e-16 58.7 0.1 1.5e-15 57.6 0.1 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 RLN73764.1 - 3.3e-09 36.3 0.1 1.2e-08 34.5 0.1 2.0 1 0 0 1 1 1 1 S4 domain TruB_N PF01509.18 RLN73764.1 - 0.038 14.4 0.0 0.068 13.5 0.0 1.3 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) Ribosomal_L9_N PF01281.19 RLN73765.1 - 1.1e-18 66.5 0.2 2.3e-18 65.5 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 RLN73765.1 - 6.7e-05 23.3 0.4 0.00037 20.9 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L9, C-terminal domain JHY PF15261.6 RLN73770.1 - 7.2e-21 75.3 3.1 7.2e-21 75.3 3.1 3.1 3 1 0 3 3 3 1 Jhy protein BBP1_C PF15272.6 RLN73770.1 - 0.23 11.3 3.7 0.14 12.0 0.9 2.0 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Arm PF00514.23 RLN73771.1 - 1.1e-58 193.5 10.4 5e-07 29.5 0.0 11.2 11 0 0 11 11 11 11 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN73771.1 - 2.8e-16 59.6 28.6 0.00047 20.6 0.1 8.4 6 4 4 10 10 10 5 HEAT-like repeat HEAT_2 PF13646.6 RLN73771.1 - 3.1e-11 43.5 27.7 0.0048 17.3 1.6 5.4 1 1 3 5 5 5 5 HEAT repeats HEAT PF02985.22 RLN73771.1 - 2.9e-07 30.1 18.7 0.58 10.6 0.0 9.0 11 1 1 12 12 11 2 HEAT repeat Arm_2 PF04826.13 RLN73771.1 - 3.1e-07 30.1 0.0 1.2 8.5 0.0 4.8 1 1 2 4 4 4 3 Armadillo-like V-ATPase_H_N PF03224.14 RLN73771.1 - 4e-07 29.6 0.0 0.042 13.1 0.0 3.3 1 1 1 2 2 2 2 V-ATPase subunit H HEAT_PBS PF03130.16 RLN73771.1 - 4.2e-07 30.0 39.7 0.15 12.8 0.4 11.1 11 0 0 11 11 11 3 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 RLN73771.1 - 5.2e-06 26.4 0.2 1 9.4 0.0 4.9 4 1 2 6 6 6 2 Spinocerebellar ataxia type 10 protein domain RPAP1_C PF08620.10 RLN73771.1 - 9.4e-06 25.6 1.1 19 5.4 0.0 6.0 6 0 0 6 6 6 0 RPAP1-like, C-terminal DUF4800 PF16057.5 RLN73771.1 - 1.1e-05 24.9 0.0 0.076 12.3 0.0 3.7 2 2 2 4 4 4 2 Domain of unknown function (DUF4800) Acyl-CoA_dh_N PF02771.16 RLN73771.1 - 0.00049 20.7 5.3 9.3 7.0 0.1 7.2 5 5 4 9 9 9 1 Acyl-CoA dehydrogenase, N-terminal domain Vitellogenin_N PF01347.22 RLN73771.1 - 0.00089 17.8 0.1 1.1 7.5 0.0 2.7 1 1 2 3 3 3 2 Lipoprotein amino terminal region UNC45-central PF11701.8 RLN73771.1 - 0.0015 18.6 0.0 5.5 6.9 0.0 3.5 2 1 2 4 4 4 2 Myosin-binding striated muscle assembly central Nuc_N PF14448.6 RLN73771.1 - 0.0036 17.1 0.9 5.6 6.9 0.0 5.2 7 0 0 7 7 7 1 Nuclease N terminal Aconitase_B_N PF11791.8 RLN73771.1 - 0.0089 16.1 5.4 4.7 7.3 0.1 5.5 2 1 3 6 6 6 1 Aconitate B N-terminal domain DUF3669 PF12417.8 RLN73771.1 - 0.02 15.1 0.0 18 5.6 0.0 3.4 3 0 0 3 3 3 0 Zinc finger protein Csc2 PF18320.1 RLN73771.1 - 0.031 13.2 0.0 0.3 10.0 0.0 2.3 2 0 0 2 2 2 0 Csc2 Crispr Pico_P2B PF01552.17 RLN73771.1 - 0.11 12.6 0.0 1.2e+02 2.9 0.0 4.6 4 1 1 6 6 6 0 Picornavirus 2B protein Succ_CoA_lig PF13607.6 RLN73771.1 - 3.4 7.5 11.0 13 5.6 0.2 5.1 3 2 1 5 5 5 0 Succinyl-CoA ligase like flavodoxin domain LRR_6 PF13516.6 RLN73778.1 - 0.0095 15.9 1.8 0.03 14.4 0.1 2.8 3 0 0 3 3 3 1 Leucine Rich repeat Pkinase PF00069.25 RLN73779.1 - 3e-49 167.8 0.0 4.3e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN73779.1 - 3.4e-46 157.6 0.0 4.5e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PTP_tm PF18861.1 RLN73779.1 - 0.018 15.1 0.4 0.039 14.0 0.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Adeno_E3_CR2 PF02439.15 RLN73779.1 - 0.018 14.7 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Haspin_kinase PF12330.8 RLN73779.1 - 0.044 12.7 0.1 0.14 11.0 0.1 1.9 1 1 0 1 1 1 0 Haspin like kinase domain Protocadherin PF08374.11 RLN73779.1 - 0.17 11.8 0.9 0.26 11.3 0.0 1.6 2 0 0 2 2 2 0 Protocadherin SKG6 PF08693.10 RLN73779.1 - 4.4 6.8 7.0 9.7 5.7 7.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Voltage_CLC PF00654.20 RLN73780.1 - 2.3e-11 43.5 4.3 8.6e-11 41.7 0.3 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel PX PF00787.24 RLN73787.1 - 7.6e-05 22.7 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 PX domain AAA PF00004.29 RLN73788.1 - 2.2e-18 67.0 1.0 7.6e-16 58.7 0.1 2.9 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN73788.1 - 2.3e-07 31.3 0.1 6.3e-07 29.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 RLN73788.1 - 1e-05 25.6 0.1 6.2e-05 23.0 0.1 2.3 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RLN73788.1 - 0.00092 19.5 0.1 0.0076 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 RLN73788.1 - 0.0011 18.2 0.0 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 RLN73788.1 - 0.0071 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RLN73788.1 - 0.0072 16.5 0.3 0.03 14.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RLN73788.1 - 0.011 15.6 1.2 0.026 14.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 RLN73788.1 - 0.02 14.6 0.1 0.054 13.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RLN73788.1 - 0.026 13.8 0.2 0.27 10.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_6 PF12774.7 RLN73788.1 - 0.039 12.9 0.4 0.34 9.8 0.0 2.1 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AAA_28 PF13521.6 RLN73788.1 - 0.046 14.0 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RLN73788.1 - 0.05 14.1 0.0 0.15 12.6 0.0 1.9 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 RLN73788.1 - 0.053 13.2 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 RLN73788.1 - 0.055 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 RLN73788.1 - 0.07 13.5 0.1 0.21 12.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_7 PF12775.7 RLN73788.1 - 0.08 12.4 0.1 0.21 11.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 RLN73788.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 RLN73788.1 - 0.13 12.6 2.7 0.35 11.2 0.2 2.5 3 1 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 RLN73788.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Herpes_UL92 PF03048.14 RLN73788.1 - 0.24 11.1 2.1 0.28 10.9 0.2 1.9 2 0 0 2 2 2 0 UL92 family AAA_18 PF13238.6 RLN73788.1 - 0.25 11.9 2.5 0.47 11.0 0.0 2.7 4 0 0 4 4 2 0 AAA domain AAA PF00004.29 RLN73789.1 - 8.4e-18 65.1 0.0 2.9e-16 60.1 0.0 2.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN73789.1 - 2.9e-06 27.8 0.0 7.8e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 RLN73789.1 - 3.9e-05 23.7 0.0 0.00015 21.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 RLN73789.1 - 0.00057 19.1 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 RLN73789.1 - 0.00096 19.4 0.1 0.0045 17.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 RLN73789.1 - 0.0023 17.7 0.1 0.0046 16.7 0.1 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RLN73789.1 - 0.0031 17.7 0.4 0.015 15.5 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 RLN73789.1 - 0.0085 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RLN73789.1 - 0.011 16.3 0.1 0.056 14.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RLN73789.1 - 0.011 15.9 0.0 0.049 13.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 RLN73789.1 - 0.014 15.1 0.1 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 RLN73789.1 - 0.019 15.3 0.0 0.06 13.7 0.0 1.9 2 0 0 2 2 1 0 RNA helicase ABC_tran PF00005.27 RLN73789.1 - 0.024 15.2 0.0 0.082 13.4 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_19 PF13245.6 RLN73789.1 - 0.04 14.3 0.4 0.092 13.1 0.4 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RLN73789.1 - 0.054 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 RLN73789.1 - 0.06 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 RLN73789.1 - 0.071 13.1 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 RLN73789.1 - 0.077 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 RLN73789.1 - 0.084 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.18 RLN73789.1 - 0.096 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 RLN73789.1 - 0.1 12.2 0.1 0.28 10.7 0.1 1.8 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 RLN73789.1 - 0.17 11.8 0.1 0.45 10.4 0.1 1.8 1 1 0 1 1 1 0 NACHT domain Ysc84 PF04366.12 RLN73792.1 - 4.7e-20 71.6 0.0 6.3e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator DUF2563 PF10817.8 RLN73792.1 - 0.081 13.5 0.0 0.11 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2563) RecO_C PF02565.15 RLN73792.1 - 0.086 12.6 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Recombination protein O C terminal Mob1_phocein PF03637.17 RLN73795.1 - 0.00028 20.9 0.0 0.011 15.8 0.1 2.1 2 0 0 2 2 2 2 Mob1/phocein family DUF3943 PF13084.6 RLN73795.1 - 0.063 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3943) OrfB_Zn_ribbon PF07282.11 RLN73796.1 - 1e-06 28.6 1.6 0.035 14.0 0.2 2.8 2 0 0 2 2 2 2 Putative transposase DNA-binding domain PIP5K PF01504.18 RLN73797.1 - 3.7e-40 137.9 0.3 1.5e-29 103.1 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 RLN73797.1 - 3.3e-24 85.4 0.1 6.4e-24 84.4 0.1 1.4 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 RLN73797.1 - 1.8e-14 53.6 14.4 1.8e-14 53.6 14.4 2.2 2 0 0 2 2 2 1 FYVE zinc finger PDZ_6 PF17820.1 RLN73797.1 - 4e-06 26.6 0.1 1.3e-05 24.9 0.1 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RLN73797.1 - 7.4e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain DLH PF01738.18 RLN73798.1 - 3.6e-20 72.5 0.1 5.4e-20 71.9 0.1 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 RLN73798.1 - 0.085 12.1 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Dpy-30 PF05186.13 RLN73799.1 - 5.2e-11 42.1 0.1 1.3e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 Dpy-30 motif YhhN PF07947.14 RLN73799.1 - 0.0062 16.2 0.2 0.01 15.5 0.2 1.3 1 0 0 1 1 1 1 YhhN family DAGK_cat PF00781.24 RLN73799.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain DUF2383 PF09537.10 RLN73799.1 - 3.7 7.9 6.5 0.67 10.3 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) LRR_8 PF13855.6 RLN73800.1 - 3.2e-51 170.9 47.5 7.9e-10 38.4 2.7 8.7 3 3 5 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 RLN73800.1 - 5.8e-36 121.9 42.6 1.2e-05 25.5 2.1 10.4 5 2 8 13 13 13 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN73800.1 - 1.4e-07 31.2 13.0 0.067 12.7 0.3 4.8 1 1 3 5 5 5 3 Leucine-rich repeat LRR_1 PF00560.33 RLN73800.1 - 2e-07 30.6 40.5 1 10.1 0.2 13.6 13 3 0 13 13 13 2 Leucine Rich Repeat LRR_6 PF13516.6 RLN73800.1 - 2.5e-06 27.1 48.3 1.1 9.5 0.1 13.7 15 0 0 15 15 15 5 Leucine Rich repeat DUF5325 PF17259.2 RLN73811.1 - 0.19 11.6 2.8 0.71 9.8 2.8 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5325) WXG100 PF06013.12 RLN73813.1 - 0.38 11.0 13.8 0.1 12.9 10.3 1.8 2 0 0 2 2 2 0 Proteins of 100 residues with WXG PARG_cat PF05028.14 RLN73814.1 - 3.3e-91 306.1 0.0 1.3e-90 304.1 0.0 1.8 1 1 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) DDE_1 PF03184.19 RLN73816.1 - 1.7e-12 47.4 0.0 2.8e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 RLN73816.1 - 0.0011 18.7 0.0 1.7 8.4 0.0 2.6 2 0 0 2 2 2 2 DDE superfamily endonuclease adh_short PF00106.25 RLN73824.1 - 1.8e-17 63.4 0.5 2.1e-17 63.2 0.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN73824.1 - 3.3e-11 43.2 0.4 4e-11 42.9 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN73824.1 - 2.9e-07 30.6 0.1 3.5e-07 30.3 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN73824.1 - 0.0041 16.6 0.0 0.005 16.3 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 RLN73824.1 - 0.031 13.5 0.1 0.032 13.5 0.1 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 RLN73824.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.0 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase FYVE PF01363.21 RLN73825.1 - 0.096 12.8 8.6 0.2 11.8 8.6 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_5 PF14634.6 RLN73825.1 - 0.29 11.1 11.6 0.52 10.3 11.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain HHH_3 PF12836.7 RLN73826.1 - 4.2e-31 107.0 0.0 2e-14 53.6 0.0 2.3 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH PF00633.23 RLN73826.1 - 5.5e-18 63.8 0.3 0.0008 19.2 0.0 4.4 3 1 1 4 4 4 4 Helix-hairpin-helix motif PsbU PF06514.11 RLN73826.1 - 2.7e-12 46.5 0.0 2.2e-06 27.6 0.0 2.4 1 1 1 2 2 2 2 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_5 PF14520.6 RLN73826.1 - 8.4e-09 35.9 0.7 0.0044 17.6 0.1 4.0 1 1 1 3 3 3 2 Helix-hairpin-helix domain Exo_endo_phos PF03372.23 RLN73826.1 - 2e-08 34.0 0.1 1.2e-07 31.5 0.1 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HHH_2 PF12826.7 RLN73826.1 - 1.6e-06 28.1 0.1 0.3 11.2 0.0 4.2 3 1 1 4 4 4 2 Helix-hairpin-helix motif HHH_8 PF14716.6 RLN73826.1 - 0.0001 22.6 0.2 1.4 9.4 0.0 4.3 2 2 2 4 4 4 1 Helix-hairpin-helix domain HHH_6 PF14579.6 RLN73826.1 - 0.097 12.9 0.0 19 5.6 0.0 3.3 1 1 1 3 3 3 0 Helix-hairpin-helix motif Transposase_20 PF02371.16 RLN73826.1 - 0.11 12.8 0.1 26 5.2 0.0 3.1 2 1 1 3 3 3 0 Transposase IS116/IS110/IS902 family ABC2_membrane PF01061.24 RLN73830.1 - 6.8e-31 107.3 28.3 6.8e-31 107.3 28.3 1.7 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN73830.1 - 2.1e-11 43.6 0.1 2.1e-11 43.6 0.1 2.3 2 0 0 2 2 2 1 CDR ABC transporter PDR_assoc PF08370.11 RLN73830.1 - 0.11 12.3 0.0 0.11 12.3 0.0 3.1 3 1 0 3 3 3 0 Plant PDR ABC transporter associated GRASP55_65 PF04495.14 RLN73831.1 - 7.7e-55 185.0 0.0 2e-41 141.5 0.0 2.3 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 RLN73831.1 - 1.6e-07 31.5 0.0 0.011 16.1 0.0 2.8 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 RLN73831.1 - 6.1e-06 26.0 0.0 0.049 13.5 0.0 2.9 3 0 0 3 3 3 2 PDZ domain Hid1 PF12722.7 RLN73831.1 - 2.9 5.9 3.9 3.8 5.5 3.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SPATA3 PF15662.5 RLN73831.1 - 4.1 8.0 8.0 6.6 7.3 8.0 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Pkinase PF00069.25 RLN73832.1 - 9.9e-52 175.9 0.0 1.3e-51 175.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN73832.1 - 3e-32 111.9 0.0 4.2e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN73832.1 - 0.00046 19.6 0.0 0.00077 18.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RLN73832.1 - 0.0027 16.7 0.5 0.0052 15.8 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 RLN73832.1 - 0.0045 16.9 0.1 0.066 13.1 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN73832.1 - 0.0067 15.2 1.0 0.022 13.5 0.0 2.1 3 0 0 3 3 3 1 Fungal protein kinase Pkinase PF00069.25 RLN73833.1 - 2.2e-45 155.1 0.0 3.1e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN73833.1 - 9.5e-25 87.3 0.0 2.2e-24 86.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN73833.1 - 1.9e-05 24.2 0.5 0.00058 19.3 0.0 2.4 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RLN73833.1 - 5.4e-05 22.1 0.0 0.00018 20.4 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 RLN73833.1 - 0.006 15.6 0.0 0.011 14.7 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RLN73833.1 - 0.0086 16.0 2.6 0.009 16.0 0.4 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF4605 PF15378.6 RLN73834.1 - 0.0047 16.8 0.3 0.0074 16.1 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4605) DUF3638 PF12340.8 RLN73835.1 - 0.0086 15.4 0.1 0.26 10.6 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3638) Pkinase PF00069.25 RLN73836.1 - 2e-30 106.0 0.0 7.8e-18 64.8 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN73836.1 - 1.7e-11 43.9 0.0 1.3e-07 31.2 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase DDHD PF02862.17 RLN73844.1 - 2.7e-29 102.9 1.2 8.4e-23 81.7 0.0 2.4 1 1 1 2 2 2 2 DDHD domain PX PF00787.24 RLN73844.1 - 5.3e-15 55.4 0.0 1.1e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 PX domain PH PF00169.29 RLN73844.1 - 2e-10 41.1 0.1 3e-06 27.7 0.4 2.6 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 RLN73844.1 - 0.046 14.1 0.3 0.15 12.5 0.3 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain PH_8 PF15409.6 RLN73844.1 - 0.059 13.7 0.0 0.51 10.7 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Glyco_hydro_3 PF00933.21 RLN73845.1 - 5.5e-52 177.1 0.0 7.2e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN73845.1 - 2.6e-37 128.8 0.0 4.6e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RLN73845.1 - 5.8e-15 55.2 0.0 1.4e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Cullin_binding PF03556.15 RLN73847.1 - 5.9e-35 120.3 1.1 9e-35 119.7 1.1 1.3 1 0 0 1 1 1 1 Cullin binding AAA_22 PF13401.6 RLN73851.1 - 0.044 14.1 0.0 0.43 10.9 0.0 2.7 3 1 0 3 3 3 0 AAA domain EmrE PF13536.6 RLN73851.1 - 0.099 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative multidrug resistance efflux transporter RNA_helicase PF00910.22 RLN73851.1 - 0.14 12.6 0.0 0.75 10.2 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Sec15 PF04091.12 RLN73854.1 - 0.01 15.2 0.1 0.012 15.1 0.1 1.0 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like DUF4486 PF14858.6 RLN73862.1 - 0.00084 18.0 0.1 0.016 13.7 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4486) SWI-SNF_Ssr4 PF08549.10 RLN73863.1 - 3.1 6.3 10.7 4 6.0 10.7 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) OTU PF02338.19 RLN73865.1 - 1.2e-26 93.7 0.0 1.2e-26 93.7 0.0 2.2 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 RLN73865.1 - 4e-07 29.8 1.8 5.7e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase C65 Otubain DUF3584 PF12128.8 RLN73865.1 - 0.3 8.6 22.0 0.41 8.1 22.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Phage_lysozyme2 PF18013.1 RLN73865.1 - 1.2 9.2 4.7 2.1 8.3 4.4 1.7 1 1 0 1 1 1 0 Phage tail lysozyme V_ATPase_I PF01496.19 RLN73865.1 - 5 4.9 12.4 6.2 4.6 12.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SIN1_PH PF16979.5 RLN73866.1 - 0.0002 21.6 0.3 0.00043 20.5 0.3 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology CRIM PF16978.5 RLN73866.1 - 0.014 15.5 0.0 0.028 14.6 0.0 1.6 1 1 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), middle CRIM domain NTP_transferase PF00483.23 RLN73867.1 - 1.8e-24 86.7 0.0 2.6e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 RLN73867.1 - 3.5e-08 32.9 9.2 2e-06 27.3 0.3 4.0 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 RLN73867.1 - 0.0036 17.7 0.0 0.0071 16.7 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 RLN73867.1 - 0.039 12.1 0.1 0.059 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 RLN73867.1 - 1.4 8.8 3.7 5 7.0 0.1 3.2 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase Sulfotransfer_1 PF00685.27 RLN73868.1 - 5.2e-09 36.0 0.0 1.7e-07 31.0 0.0 2.7 1 1 0 1 1 1 1 Sulfotransferase domain Asp_Arg_Hydrox PF05118.15 RLN73868.1 - 8.1e-07 29.0 0.2 1.6e-06 28.1 0.2 1.5 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Sulfotransfer_3 PF13469.6 RLN73868.1 - 2e-05 25.1 0.0 0.0049 17.3 0.0 2.9 2 1 0 2 2 2 1 Sulfotransferase family Ribosomal_L18 PF17135.4 RLN73869.1 - 5.6e-75 250.9 3.3 6.2e-75 250.7 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 RLN73869.1 - 0.0038 17.9 0.1 0.0094 16.6 0.1 1.8 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Pkinase PF00069.25 RLN73870.1 - 5e-63 212.9 0.0 8.5e-63 212.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 RLN73870.1 - 1.1e-59 198.5 1.1 4.8e-19 68.2 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 RLN73870.1 - 6.2e-30 104.3 0.0 1.5e-29 103.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 RLN73870.1 - 0.088 12.7 0.0 0.42 10.5 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family KIAA1430 PF13879.6 RLN73871.1 - 0.0042 17.8 2.0 0.0042 17.8 2.0 4.9 3 2 1 4 4 4 2 KIAA1430 homologue LBR_tudor PF09465.10 RLN73871.1 - 0.092 12.6 0.8 0.18 11.6 0.8 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain DUF948 PF06103.11 RLN73871.1 - 0.23 11.8 2.5 0.96 9.7 2.5 2.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1825 PF08855.10 RLN73871.1 - 4.6 7.2 8.4 0.43 10.5 3.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) RRP36 PF06102.12 RLN73872.1 - 3.7e-45 153.9 28.8 4.6e-45 153.6 28.8 1.1 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 HEAT_2 PF13646.6 RLN73873.1 - 0.18 12.2 2.8 0.76 10.2 0.2 3.5 2 0 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.6 RLN73873.1 - 0.46 11.0 0.0 0.46 11.0 0.0 5.7 5 1 0 5 5 5 0 HEAT-like repeat Arm_2 PF04826.13 RLN73873.1 - 0.97 8.8 6.4 1.5 8.2 0.1 3.7 4 0 0 4 4 4 0 Armadillo-like Arm PF00514.23 RLN73873.1 - 1.7 8.8 30.6 1.1 9.5 0.0 9.4 10 0 0 10 10 10 0 Armadillo/beta-catenin-like repeat GHMP_kinases_N PF00288.26 RLN73874.1 - 0.19 12.0 0.2 0.19 12.0 0.2 3.3 3 0 0 3 3 3 0 GHMP kinases N terminal domain Kinesin PF00225.23 RLN73888.1 - 5.3e-72 242.5 0.5 5.9e-72 242.4 0.5 1.0 1 0 0 1 1 1 1 Kinesin motor domain STAG PF08514.11 RLN73889.1 - 1e-27 96.3 0.0 1e-27 96.3 0.0 2.8 3 0 0 3 3 3 1 STAG domain Cnd1 PF12717.7 RLN73889.1 - 0.0077 16.3 2.3 0.032 14.3 0.3 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RLN73889.1 - 0.066 13.5 1.0 50 4.6 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat Rotamase PF00639.21 RLN73889.1 - 0.3 12.1 2.8 4.1 8.4 0.4 3.5 2 0 0 2 2 2 0 PPIC-type PPIASE domain Glyco_hydro_3_C PF01915.22 RLN73890.1 - 5.8e-50 170.1 0.0 9.1e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 RLN73890.1 - 1.9e-36 126.1 0.0 2.8e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 RLN73890.1 - 1.8e-12 47.1 0.0 4.1e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DEAD PF00270.29 RLN73891.1 - 2.2e-44 151.3 0.1 4.6e-44 150.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN73891.1 - 1.1e-30 106.2 0.2 4.5e-29 101.0 0.2 3.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 RLN73891.1 - 0.00084 19.6 0.0 0.003 17.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain BSP_II PF05432.11 RLN73891.1 - 0.006 16.3 27.9 0.006 16.3 27.9 2.6 2 1 0 2 2 2 1 Bone sialoprotein II (BSP-II) HECT PF00632.25 RLN73892.1 - 2.1e-97 326.3 0.1 2.4e-97 326.1 0.1 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Terminase_3C PF17288.2 RLN73892.1 - 0.15 12.4 0.0 0.24 11.8 0.0 1.2 1 0 0 1 1 1 0 Terminase RNAseH like domain Thr_dehydrat_C PF00585.18 RLN73893.1 - 2.3e-38 129.8 0.5 6.2e-25 86.8 0.0 3.2 2 1 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase PALP PF00291.25 RLN73893.1 - 2.9e-29 102.4 0.3 4.3e-29 101.9 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PALP PF00291.25 RLN73894.1 - 7.1e-33 114.3 0.0 8.5e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme D123 PF07065.14 RLN73896.1 - 6.9e-79 265.2 0.0 8.9e-79 264.8 0.0 1.1 1 0 0 1 1 1 1 D123 Patched PF02460.18 RLN73897.1 - 0.013 13.7 0.0 0.015 13.4 0.0 1.0 1 0 0 1 1 1 0 Patched family MCM PF00493.23 RLN73902.1 - 7.4e-101 335.9 0.1 1e-100 335.5 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RLN73902.1 - 6.1e-29 100.4 0.1 1.1e-28 99.6 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 RLN73902.1 - 7.1e-18 65.1 0.3 1.7e-17 63.9 0.3 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 RLN73902.1 - 7.1e-10 38.6 0.0 1.4e-08 34.4 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RLN73902.1 - 0.00033 20.7 0.0 0.00071 19.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 RLN73902.1 - 0.0027 17.4 0.0 0.0056 16.4 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 RLN73902.1 - 0.0045 16.8 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FYVE PF01363.21 RLN73903.1 - 0.0032 17.6 7.4 0.0063 16.6 7.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN73903.1 - 0.33 11.2 2.8 0.61 10.3 2.8 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger PRC PF05239.16 RLN73904.1 - 0.019 15.0 0.0 0.057 13.5 0.0 1.7 1 0 0 1 1 1 0 PRC-barrel domain Trypsin_2 PF13365.6 RLN73905.1 - 7.3e-17 62.7 0.5 7.3e-17 62.7 0.5 2.0 2 0 0 2 2 2 1 Trypsin-like peptidase domain Peptidase_S46 PF10459.9 RLN73905.1 - 0.0021 16.8 0.2 0.0021 16.8 0.2 1.7 2 0 0 2 2 2 1 Peptidase S46 Trypsin PF00089.26 RLN73905.1 - 0.0023 17.8 4.1 0.0023 17.8 4.1 2.4 2 1 0 2 2 2 1 Trypsin FYVE PF01363.21 RLN73906.1 - 0.13 12.4 10.0 0.34 11.1 10.0 1.7 1 1 0 1 1 1 0 FYVE zinc finger FYVE PF01363.21 RLN73907.1 - 0.17 12.0 11.5 0.85 9.8 11.3 2.1 1 1 1 2 2 2 0 FYVE zinc finger ADH_zinc_N PF00107.26 RLN73909.1 - 2.3e-16 60.0 0.5 4.5e-16 59.0 0.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN73909.1 - 3.1e-10 41.2 0.5 6.5e-10 40.2 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN73909.1 - 2.9e-05 23.9 0.0 8.8e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ThiF PF00899.21 RLN73909.1 - 0.086 12.2 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 ThiF family Ank_2 PF12796.7 RLN73916.1 - 6.8e-34 116.3 5.9 1.4e-16 60.8 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN73916.1 - 1.8e-21 75.9 3.6 5.1e-06 26.6 0.0 5.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN73916.1 - 6.7e-21 73.8 3.5 5.9e-05 23.3 0.0 6.1 5 1 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 RLN73916.1 - 2.9e-20 72.4 0.2 5.6e-09 36.4 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN73916.1 - 2.9e-18 64.0 0.1 0.0064 16.9 0.0 5.9 5 0 0 5 5 5 5 Ankyrin repeat PAP_assoc PF03828.19 RLN73917.1 - 1.5e-11 44.3 0.0 4.2e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase cNMP_binding PF00027.29 RLN73918.1 - 2.5e-45 152.5 0.5 6.3e-13 48.6 0.0 5.5 5 0 0 5 5 5 4 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN73918.1 - 8.4e-36 123.4 66.8 2.4e-14 53.2 10.6 4.5 4 0 0 4 4 4 4 Ion transport protein Transformer PF06495.11 RLN73918.1 - 0.051 13.7 0.1 0.051 13.7 0.1 1.9 2 0 0 2 2 2 0 Fruit fly transformer protein Ion_trans_2 PF07885.16 RLN73918.1 - 7.6 6.6 32.7 0.63 10.0 0.9 6.0 5 0 0 5 5 5 0 Ion channel Nuf2 PF03800.14 RLN73919.1 - 5.8e-43 146.4 0.1 4.1e-42 143.6 0.0 2.1 2 0 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 RLN73919.1 - 5e-17 62.0 12.1 5e-17 62.0 12.1 3.8 1 1 3 4 4 4 1 Designed helical repeat protein 10 domain BLOC1_2 PF10046.9 RLN73919.1 - 0.014 15.7 16.0 0.068 13.5 0.2 4.5 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Wax2_C PF12076.8 RLN73919.1 - 0.049 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 WAX2 C-terminal domain Baculo_PEP_C PF04513.12 RLN73919.1 - 0.33 11.0 3.8 1.6 8.8 2.0 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TSC22 PF01166.18 RLN73919.1 - 1.2 9.5 8.7 0.79 10.1 0.4 3.4 3 0 0 3 3 3 0 TSC-22/dip/bun family GAS PF13851.6 RLN73919.1 - 3.8 6.8 37.5 1.5 8.2 4.6 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding JIP_LZII PF16471.5 RLN73919.1 - 4.2 7.6 22.0 0.75 10.0 0.5 4.7 3 3 2 5 5 5 0 JNK-interacting protein leucine zipper II WD40 PF00400.32 RLN73920.1 - 8.6e-13 48.6 7.1 0.11 13.4 0.1 9.7 10 0 0 10 10 10 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN73920.1 - 2e-06 28.0 0.0 4.1 7.8 0.0 5.8 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Prothymosin PF03247.14 RLN73920.1 - 0.0072 16.8 11.7 0.0072 16.8 11.7 3.3 3 0 0 3 3 3 1 Prothymosin/parathymosin family PPP4R2 PF09184.11 RLN73920.1 - 0.14 11.8 6.5 0.45 10.0 6.5 1.9 1 0 0 1 1 1 0 PPP4R2 RRN3 PF05327.11 RLN73920.1 - 2.5 6.6 7.1 4.4 5.7 7.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HALZ PF02183.18 RLN73920.1 - 3.4 8.0 8.3 0.19 12.0 0.8 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper Drc1-Sld2 PF11719.8 RLN73920.1 - 4.1 6.8 11.1 13 5.2 11.1 1.9 1 0 0 1 1 1 0 DNA replication and checkpoint protein LCM PF04072.14 RLN73927.1 - 2.3e-40 138.5 0.0 3.3e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase LCM PF04072.14 RLN73928.1 - 2.7e-40 138.3 0.0 4.2e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase LCM PF04072.14 RLN73929.1 - 4.7e-32 111.4 0.1 8.3e-32 110.7 0.0 1.4 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Peptidase_C2 PF00648.21 RLN73930.1 - 2.4e-53 181.1 0.0 3.4e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease WW PF00397.26 RLN73930.1 - 9.4e-09 35.2 0.3 3e-08 33.6 0.3 1.9 1 0 0 1 1 1 1 WW domain C2 PF00168.30 RLN73930.1 - 1.7e-08 34.7 0.0 4.4e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 C2 domain Calpain_III PF01067.22 RLN73930.1 - 0.0013 19.0 0.0 0.0039 17.5 0.0 1.8 1 0 0 1 1 1 1 Calpain large subunit, domain III LUC7 PF03194.15 RLN73931.1 - 2.8e-73 246.7 2.1 3.9e-73 246.2 2.1 1.2 1 0 0 1 1 1 1 LUC7 N_terminus zf_C2H2_13 PF18508.1 RLN73931.1 - 0.017 14.7 0.0 0.051 13.2 0.0 1.8 1 0 0 1 1 1 0 Zinc finger domain Ribonuc_L-PSP PF01042.21 RLN73932.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Endoribonuclease L-PSP LCM PF04072.14 RLN73933.1 - 6.7e-07 29.4 0.0 9.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase LCM PF04072.14 RLN73935.1 - 3.2e-37 128.3 0.0 4.8e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase SAM_MT PF04445.13 RLN73935.1 - 0.023 14.1 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase LCM PF04072.14 RLN73936.1 - 7e-42 143.5 0.2 1.5e-41 142.4 0.1 1.6 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Asp PF00026.23 RLN73937.1 - 1.8e-38 132.7 0.1 1.8e-22 80.2 0.0 3.1 3 0 0 3 3 3 3 Eukaryotic aspartyl protease Atg14 PF10186.9 RLN73937.1 - 7.4e-25 87.7 0.1 2.8e-19 69.4 0.0 2.3 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 TAXi_N PF14543.6 RLN73937.1 - 4.3e-10 40.1 1.0 2.3e-09 37.7 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Cwf_Cwc_15 PF04889.12 RLN73937.1 - 0.0048 16.7 6.2 0.007 16.1 6.2 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Asp_protease_2 PF13650.6 RLN73937.1 - 0.019 15.6 0.0 7.8 7.2 0.0 3.2 3 0 0 3 3 3 0 Aspartyl protease APG6 PF04111.12 RLN73937.1 - 0.037 14.0 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Apg6 BARA domain RXT2_N PF08595.11 RLN73937.1 - 0.048 13.7 2.1 0.089 12.8 2.1 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 RLN73937.1 - 0.065 11.3 6.1 0.086 10.9 6.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi TAXi_C PF14541.6 RLN73937.1 - 0.078 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal RNA_pol_3_Rpc31 PF11705.8 RLN73937.1 - 0.081 13.2 6.3 0.13 12.5 6.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FAM176 PF14851.6 RLN73937.1 - 0.11 12.1 1.0 0.23 11.1 1.0 1.4 1 0 0 1 1 1 0 FAM176 family DUF2457 PF10446.9 RLN73937.1 - 0.12 11.5 12.9 0.21 10.7 12.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4611 PF15387.6 RLN73937.1 - 0.21 11.9 4.6 0.38 11.0 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.6 RLN73937.1 - 0.41 11.0 8.2 0.79 10.1 8.2 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.13 RLN73937.1 - 1.5 8.7 5.7 2.3 8.0 5.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region GCIP PF13324.6 RLN73937.1 - 3.4 7.2 4.8 5.5 6.5 4.8 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Glyco_hydro_17 PF00332.18 RLN73938.1 - 0.00011 21.9 2.4 0.00024 20.8 0.5 2.3 2 1 1 3 3 3 1 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.13 RLN73938.1 - 0.00087 18.4 0.5 0.0022 17.0 0.5 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Fer4_7 PF12838.7 RLN73939.1 - 0.00061 20.3 2.2 0.0012 19.4 2.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 RLN73939.1 - 0.024 14.4 2.6 0.13 12.1 1.5 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_9 PF13187.6 RLN73939.1 - 0.034 14.3 1.1 0.06 13.5 1.1 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 RLN73939.1 - 0.44 11.1 6.8 0.35 11.5 1.8 2.4 1 1 2 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I DUF3336 PF11815.8 RLN73940.1 - 2.6e-21 75.8 0.3 4.8e-21 74.9 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 RLN73940.1 - 1.2e-17 64.7 0.0 1.3e-16 61.4 0.0 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase HnRNP_M PF11532.8 RLN73942.1 - 0.098 12.9 0.5 0.66 10.2 0.3 2.2 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein M TAFII28 PF04719.14 RLN73943.1 - 9.8e-20 70.4 0.1 6e-13 48.7 0.0 2.3 2 0 0 2 2 2 2 hTAFII28-like protein conserved region Sporozoite_P67 PF05642.11 RLN73943.1 - 0.00015 20.1 1.5 0.00019 19.7 1.5 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen CDC45 PF02724.14 RLN73943.1 - 0.0071 14.7 4.8 0.0069 14.7 4.8 1.1 1 0 0 1 1 1 1 CDC45-like protein Myc_N PF01056.18 RLN73943.1 - 0.25 11.2 5.9 0.32 10.8 5.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Nop14 PF04147.12 RLN73943.1 - 0.26 9.4 16.4 0.32 9.2 16.4 1.0 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 RLN73943.1 - 1.4 7.6 4.6 1.6 7.4 4.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 RLN73943.1 - 6 6.1 16.6 7.4 5.8 16.6 1.1 1 0 0 1 1 1 0 BUD22 Maf PF02545.14 RLN73946.1 - 3.5e-31 108.3 0.0 4.5e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein AAA_6 PF12774.7 RLN73947.1 - 1.4e-148 494.2 0.0 1.5e-146 487.5 0.0 3.2 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN73947.1 - 1.5e-135 452.4 4.3 3.8e-135 451.0 4.3 1.8 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RLN73947.1 - 4.2e-99 331.1 0.0 1.1e-98 329.7 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 RLN73947.1 - 4.7e-68 228.3 0.2 3.6e-63 212.4 0.0 4.3 4 1 0 4 4 4 2 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 RLN73947.1 - 6.7e-31 107.1 0.3 2e-30 105.5 0.3 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RLN73947.1 - 3.3e-18 65.7 0.0 2.1e-17 63.2 0.0 2.5 1 0 0 1 1 1 1 AAA+ lid domain MT PF12777.7 RLN73947.1 - 5.5e-17 61.8 10.8 9.2e-17 61.1 10.8 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 RLN73947.1 - 5e-12 46.0 0.3 0.014 15.4 0.0 5.7 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RLN73947.1 - 2e-11 44.3 0.2 0.0094 16.2 0.0 5.7 6 0 0 6 6 6 2 AAA domain AAA PF00004.29 RLN73947.1 - 1.1e-08 35.6 0.3 0.23 11.9 0.0 5.0 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN73947.1 - 2.1e-07 31.5 1.2 0.24 11.8 0.0 5.9 5 0 0 5 5 5 1 AAA ATPase domain AAA_18 PF13238.6 RLN73947.1 - 1e-05 26.1 1.1 0.051 14.1 0.0 4.6 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 RLN73947.1 - 0.0014 18.4 3.5 2.6 7.7 0.1 4.2 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 RLN73947.1 - 0.0076 16.6 0.2 38 4.7 0.0 3.7 3 0 0 3 3 3 0 RNA helicase ResIII PF04851.15 RLN73947.1 - 0.016 15.2 0.2 8.1 6.4 0.1 2.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 RLN73947.1 - 0.018 15.2 0.8 54 3.9 0.0 4.2 4 0 0 4 4 4 0 AAA domain DUF2075 PF09848.9 RLN73947.1 - 0.032 13.5 0.1 0.087 12.0 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 RLN73947.1 - 0.033 14.2 0.0 2 8.5 0.0 3.2 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 RLN73947.1 - 0.23 10.5 0.0 0.23 10.5 0.0 4.0 5 0 0 5 5 5 0 Type II/IV secretion system protein ABC_tran PF00005.27 RLN73947.1 - 1.9 9.0 4.4 77 3.8 0.1 4.1 4 0 0 4 4 3 0 ABC transporter AAA_19 PF13245.6 RLN73947.1 - 4.4 7.6 9.2 1.9 8.8 0.1 4.6 5 0 0 5 5 5 0 AAA domain MBOAT PF03062.19 RLN73948.1 - 8.3e-37 127.3 5.9 1.2e-36 126.9 5.9 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MIP-T3_C PF17749.1 RLN73955.1 - 0.01 15.8 0.2 0.018 15.0 0.2 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region SKA2 PF16740.5 RLN73955.1 - 0.042 13.6 0.3 0.082 12.7 0.3 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 FMN_dh PF01070.18 RLN73962.1 - 4.1e-76 256.3 0.7 3.7e-63 213.7 0.2 2.0 2 0 0 2 2 2 2 FMN-dependent dehydrogenase ThiG PF05690.14 RLN73962.1 - 0.00065 19.1 0.1 0.00098 18.5 0.1 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Dus PF01207.17 RLN73962.1 - 0.074 12.1 0.0 1.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 RLN73962.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase His_biosynth PF00977.21 RLN73962.1 - 0.11 11.9 0.4 0.88 9.0 0.1 2.0 2 0 0 2 2 2 0 Histidine biosynthesis protein Laminin_G_3 PF13385.6 RLN73966.1 - 4.2e-07 30.2 0.1 2.1e-06 27.9 0.1 2.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily F5_F8_type_C PF00754.25 RLN73966.1 - 0.00092 19.3 2.7 0.1 12.7 0.0 4.0 4 0 0 4 4 4 1 F5/8 type C domain Calx-beta PF03160.14 RLN73966.1 - 0.0018 18.4 6.1 0.28 11.4 0.1 5.4 7 0 0 7 7 7 2 Calx-beta domain SBBP PF06739.11 RLN73966.1 - 4.3 7.4 5.5 3.1 7.9 0.0 3.2 3 0 0 3 3 3 0 Beta-propeller repeat Rdx PF10262.9 RLN73967.1 - 8.9e-10 38.6 0.0 1.3e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Rdx family ZF-HD_dimer PF04770.12 RLN73967.1 - 0.015 15.6 0.2 0.023 15.0 0.2 1.3 1 0 0 1 1 1 0 ZF-HD protein dimerisation region MoCF_biosynth PF00994.24 RLN73968.1 - 5.3e-57 191.5 0.9 1e-29 103.1 0.3 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain eRF1_2 PF03464.15 RLN73968.1 - 1.7e-44 151.4 0.0 3.4e-44 150.4 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 2 MoeA_N PF03453.17 RLN73968.1 - 1.1e-41 142.2 6.2 2.1e-41 141.3 6.2 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) eRF1_3 PF03465.15 RLN73968.1 - 1.1e-35 122.5 0.4 4e-35 120.7 0.0 2.2 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 RLN73968.1 - 9.6e-19 67.7 0.0 1.9e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 RLN73968.1 - 3e-10 40.5 0.0 8.6e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 RLN73968.1 - 8.7e-10 39.0 0.0 2.3e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor MoeA_C PF03454.15 RLN73968.1 - 0.12 12.6 0.0 0.38 11.0 0.0 1.9 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) ATG7_N PF16420.5 RLN73969.1 - 4.9e-56 190.6 0.0 2.2e-41 142.5 0.0 2.2 1 1 1 2 2 2 2 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 RLN73969.1 - 7.9e-48 162.9 0.0 1.2e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 RLN73969.1 - 0.0013 18.8 0.0 0.31 11.1 0.0 2.6 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase EF-hand_1 PF00036.32 RLN73970.1 - 2.3e-26 89.3 0.7 8.2e-07 28.1 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RLN73970.1 - 9.7e-25 86.8 0.3 1e-11 45.1 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair FKBP_C PF00254.28 RLN73970.1 - 1e-22 80.2 0.0 2.1e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_8 PF13833.6 RLN73970.1 - 6.8e-21 73.9 0.4 6.4e-10 38.7 0.0 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RLN73970.1 - 7e-20 69.2 1.8 0.00045 19.9 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RLN73970.1 - 8.2e-18 63.0 4.2 8.9e-05 21.8 0.1 4.6 4 0 0 4 4 4 4 EF hand WW PF00397.26 RLN73970.1 - 4.8e-07 29.8 0.2 1e-06 28.7 0.2 1.5 1 0 0 1 1 1 1 WW domain SPARC_Ca_bdg PF10591.9 RLN73970.1 - 0.00017 21.9 0.5 1 9.7 0.0 2.8 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region DUF5580 PF17743.1 RLN73970.1 - 0.038 12.5 0.2 0.1 11.1 0.2 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5580) DUF2058 PF09831.9 RLN73970.1 - 0.16 12.1 3.4 0.41 10.8 3.4 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) AMP-binding PF00501.28 RLN73971.1 - 2.8e-82 276.6 0.0 3.6e-82 276.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN73971.1 - 1.9e-17 64.0 0.1 5.8e-17 62.5 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2148 PF09918.9 RLN73971.1 - 0.085 12.9 0.1 0.24 11.5 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) MCU PF04678.13 RLN73972.1 - 1e-30 107.1 0.1 1.8e-30 106.3 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial calcium uniporter COR PF16095.5 RLN73972.1 - 1.2e-05 25.3 0.0 2.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Halogen_Hydrol PF10112.9 RLN73972.1 - 0.043 13.8 0.3 0.62 10.1 0.0 2.4 2 1 1 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF2244 PF10003.9 RLN73972.1 - 0.073 12.7 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Peptidase_C1 PF00112.23 RLN73973.1 - 1.1e-42 146.6 1.7 1.6e-42 146.1 1.7 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RLN73973.1 - 0.013 14.3 1.1 0.02 13.7 1.1 1.1 1 0 0 1 1 1 0 Peptidase C1-like family DUF4148 PF13663.6 RLN73973.1 - 1.2 9.4 3.6 1.6 9.0 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Hydrolase_4 PF12146.8 RLN73980.1 - 4.1e-05 23.0 0.1 0.00022 20.5 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN73980.1 - 6.6e-05 22.7 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN73980.1 - 8.8e-05 23.2 0.0 0.0013 19.4 0.0 2.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF3525 PF12039.8 RLN73980.1 - 0.039 12.7 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) DUF2920 PF11144.8 RLN73980.1 - 0.056 12.6 0.1 0.082 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) zf-C2H2 PF00096.26 RLN73981.1 - 9.5e-12 44.7 18.6 0.0019 18.6 5.4 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RLN73981.1 - 1.4e-08 34.8 27.0 3.7e-05 23.9 4.1 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RLN73981.1 - 3.3e-08 33.7 17.1 0.0045 17.7 0.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 RLN73981.1 - 6e-05 23.3 5.0 0.00081 19.6 1.0 2.2 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 RLN73981.1 - 0.0045 17.6 5.1 0.33 11.6 1.3 2.4 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 RLN73981.1 - 0.019 15.2 5.1 0.33 11.3 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RLN73981.1 - 0.14 12.6 4.6 1.1 9.7 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-TRAF PF02176.18 RLN73981.1 - 0.23 12.2 12.7 0.13 12.9 4.6 2.4 1 1 1 2 2 2 0 TRAF-type zinc finger AAA_25 PF13481.6 RLN73986.1 - 0.0054 16.3 0.3 0.02 14.5 0.0 2.1 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.7 RLN73986.1 - 0.041 12.8 0.0 0.068 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Y_phosphatase PF00102.27 RLN73986.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase AAA_5 PF07728.14 RLN73986.1 - 0.15 12.1 0.0 0.81 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Chordopox_A20R PF05941.13 RLN73986.1 - 0.17 10.9 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A20R protein TPR_1 PF00515.28 RLN73996.1 - 7e-17 60.5 1.8 1.8e-06 27.5 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN73996.1 - 3e-13 48.8 7.1 1.5e-06 27.8 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 RLN73996.1 - 1.4e-07 31.5 1.8 5.5e-07 29.6 1.8 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN73996.1 - 1.5e-07 31.0 1.3 0.0012 18.5 0.1 2.9 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 RLN73996.1 - 1.1e-05 25.2 0.1 0.28 11.5 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN73996.1 - 1.7e-05 24.8 0.1 0.52 10.8 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN73996.1 - 0.00015 22.3 2.6 0.00046 20.8 1.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN73996.1 - 0.023 15.0 7.7 1.2 9.5 0.0 3.6 2 1 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 RLN73996.1 - 0.027 14.5 0.3 15 5.9 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN73996.1 - 0.049 13.7 0.2 0.19 11.8 0.2 2.0 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 RLN73996.1 - 0.055 14.3 9.1 0.21 12.5 0.1 4.0 3 1 1 4 4 3 0 Tetratricopeptide repeat BCDHK_Adom3 PF10436.9 RLN73996.1 - 0.56 10.0 3.0 2.4 8.0 2.3 2.2 2 1 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase TPR_19 PF14559.6 RLN73996.1 - 1 9.9 10.1 1.3 9.6 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN73996.1 - 1.5 8.8 6.0 1.5 8.8 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ECR1_N PF14382.6 RLN73997.1 - 1.8e-12 46.8 0.0 3.9e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.9 RLN73997.1 - 2.8e-09 37.6 0.7 0.0004 21.0 0.0 2.4 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 Pkinase_Tyr PF07714.17 RLN73998.1 - 2.5e-27 95.8 0.0 3e-24 85.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN73998.1 - 1.4e-20 73.8 0.0 6e-11 42.2 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 RLN73998.1 - 0.0035 16.7 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like LRR_4 PF12799.7 RLN73998.1 - 0.05 14.1 0.0 0.33 11.5 0.0 2.2 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) bZIP_1 PF00170.21 RLN73999.1 - 7.6e-07 29.1 8.6 2.4e-06 27.5 8.6 1.9 1 0 0 1 1 1 1 bZIP transcription factor SUIM_assoc PF16619.5 RLN73999.1 - 0.058 13.5 27.9 5.2 7.2 2.7 5.6 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Complex1_LYR PF05347.15 RLN74000.1 - 8e-05 22.6 0.0 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) AC_N PF16214.5 RLN74000.1 - 0.1 11.7 0.0 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region HU-CCDC81_euk_2 PF18289.1 RLN74001.1 - 1.2e-11 44.5 0.0 3e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 WD40 PF00400.32 RLN74001.1 - 2.2e-09 37.8 0.9 0.065 14.1 0.0 5.8 5 1 0 5 5 5 3 WD domain, G-beta repeat HU-CCDC81_euk_1 PF14908.6 RLN74001.1 - 1.6e-08 34.6 0.0 5.7e-08 32.8 0.0 2.0 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 Gon7 PF08738.10 RLN74001.1 - 0.048 13.7 2.0 0.18 11.9 2.0 2.0 1 0 0 1 1 1 0 Gon7 family Snf7 PF03357.21 RLN74002.1 - 2.4e-15 56.6 9.3 3.3e-15 56.1 9.3 1.2 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 RLN74002.1 - 0.002 18.1 1.2 0.0026 17.7 1.2 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Cytochrom_B562 PF07361.11 RLN74002.1 - 1.1 9.9 11.2 0.66 10.7 3.1 3.1 2 2 1 3 3 3 0 Cytochrome b562 PNP_UDP_1 PF01048.20 RLN74003.1 - 4.7e-44 150.4 0.0 6.4e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily TCTP PF00838.17 RLN74004.1 - 3.1e-43 148.0 1.3 3.6e-43 147.8 1.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein CelTOS PF18659.1 RLN74004.1 - 0.11 13.0 0.0 0.32 11.5 0.0 1.7 1 1 1 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites Apolipoprotein PF01442.18 RLN74004.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2232 PF09991.9 RLN74004.1 - 0.17 11.0 0.2 0.25 10.5 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) EXS PF03124.14 RLN74005.1 - 1.1e-82 278.0 21.7 1.6e-82 277.5 21.7 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 RLN74005.1 - 2.8e-14 53.8 3.8 2.9e-07 30.8 0.1 2.9 1 1 2 3 3 3 3 SPX domain Angiomotin_C PF12240.8 RLN74005.1 - 0.049 13.2 0.6 0.092 12.3 0.6 1.3 1 0 0 1 1 1 0 Angiomotin C terminal His_Phos_2 PF00328.22 RLN74009.1 - 2.2e-29 103.0 0.0 3.4e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF4395 PF14340.6 RLN74010.1 - 1.9 8.8 12.1 1.2 9.5 2.9 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) Lipoxygenase PF00305.19 RLN74011.1 - 3.7e-18 65.3 1.7 4.8e-17 61.7 1.7 2.4 1 1 0 1 1 1 1 Lipoxygenase Halo_GVPC PF05465.13 RLN74011.1 - 0.52 10.6 4.6 0.65 10.3 2.6 2.2 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat LIAS_N PF16881.5 RLN74013.1 - 0.018 15.5 0.1 0.024 15.0 0.1 1.3 1 1 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family Ribosomal_S7e PF01251.18 RLN74014.1 - 2.3e-83 278.5 2.6 2.6e-83 278.3 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Pyr_redox_2 PF07992.14 RLN74015.1 - 3.2e-40 138.2 0.0 4.8e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RLN74015.1 - 0.00021 21.8 0.4 0.017 15.6 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 RLN74015.1 - 0.16 12.0 0.0 7.8 6.5 0.0 3.0 3 1 1 4 4 4 0 FAD-NAD(P)-binding PIN_8 PF18476.1 RLN74020.1 - 0.83 9.5 4.7 0.6 9.9 1.6 1.9 1 1 1 2 2 2 0 PIN like domain DARPP-32 PF05395.12 RLN74020.1 - 0.87 9.8 3.9 2 8.6 3.7 1.7 1 1 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Mating_C PF12737.7 RLN74033.1 - 0.015 14.5 3.2 0.018 14.3 3.2 1.0 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 IFT43 PF15305.6 RLN74033.1 - 0.14 12.3 1.8 0.22 11.7 1.8 1.2 1 0 0 1 1 1 0 Intraflagellar transport protein 43 Cas_Csy4 PF09618.10 RLN74033.1 - 0.26 11.4 3.4 0.37 10.9 3.4 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) SNARE_assoc PF09335.11 RLN74035.1 - 2.5e-17 63.5 6.1 2.5e-17 63.5 6.1 3.0 3 0 0 3 3 3 1 SNARE associated Golgi protein SNARE_assoc PF09335.11 RLN74036.1 - 2e-16 60.5 3.8 4.8e-16 59.3 3.8 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein MPS2 PF17060.5 RLN74036.1 - 2.5 7.3 5.7 3.6 6.7 5.7 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 V_ATPase_I PF01496.19 RLN74036.1 - 2.8 5.8 4.4 4.2 5.2 4.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_1 PF00170.21 RLN74036.1 - 4.1 7.6 11.3 13 6.0 2.4 3.3 1 1 2 3 3 3 0 bZIP transcription factor Exonuc_VII_L PF02601.15 RLN74036.1 - 6.5 6.2 14.1 11 5.5 14.1 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit TMEM223 PF14640.6 RLN74037.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein 223 RabGAP-TBC PF00566.18 RLN74038.1 - 5.4e-25 88.3 0.1 4.4e-12 46.1 0.0 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Pkinase PF00069.25 RLN74040.1 - 1.7e-54 185.0 0.0 2.6e-53 181.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN74040.1 - 3.3e-29 102.0 0.0 5e-27 94.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RLN74040.1 - 2.7e-08 33.5 0.0 4.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RLN74040.1 - 2.6e-05 23.2 0.0 3.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN74040.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN74040.1 - 0.14 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_AraC PF00165.23 RLN74040.1 - 0.15 12.2 0.0 0.42 10.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family BTK PF00779.19 RLN74041.1 - 0.12 12.3 3.6 0.14 12.0 0.9 2.3 2 0 0 2 2 2 0 BTK motif CHORD PF04968.12 RLN74041.1 - 8.2 7.2 7.7 4.6e+02 1.6 7.7 3.0 1 1 0 1 1 1 0 CHORD WLM PF08325.10 RLN74043.1 - 5e-19 69.1 0.0 8.7e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 WLM domain PUB PF09409.10 RLN74043.1 - 1e-16 60.6 0.0 1.8e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 PUB domain ubiquitin PF00240.23 RLN74043.1 - 0.036 13.8 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family LPD11 PF18824.1 RLN74043.1 - 0.14 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 11 TPH PF13868.6 RLN74044.1 - 3.7e-11 42.2 126.1 3.7e-11 42.2 126.1 1.7 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain DDRGK PF09756.9 RLN74047.1 - 1.1e-53 181.6 31.1 1.1e-53 181.6 31.1 1.4 2 0 0 2 2 2 1 DDRGK domain DUF3877 PF12993.7 RLN74047.1 - 0.038 13.9 5.6 0.073 12.9 5.6 1.5 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) Pkinase_fungal PF17667.1 RLN74047.1 - 0.22 10.3 6.0 0.33 9.7 6.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase L_lactis_ph-MCP PF06673.11 RLN74047.1 - 1.7 7.5 8.8 2.4 7.0 8.8 1.4 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein RR_TM4-6 PF06459.12 RLN74047.1 - 4.4 7.0 17.7 6.4 6.5 17.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PTPlike_phytase PF14566.6 RLN74048.1 - 1.5e-85 285.0 4.9 8.1e-50 169.0 0.7 2.3 2 0 0 2 2 2 2 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 RLN74048.1 - 0.019 14.9 0.0 4.7 7.1 0.0 2.5 2 0 0 2 2 2 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 RLN74048.1 - 0.021 14.4 0.1 1.1 8.7 0.0 2.5 3 0 0 3 3 3 0 Protein-tyrosine phosphatase TOC159_MAD PF11886.8 RLN74048.1 - 0.045 12.6 0.0 0.11 11.4 0.0 1.5 2 0 0 2 2 2 0 Translocase of chloroplast 159/132, membrane anchor domain DSPc PF00782.20 RLN74048.1 - 1.1 9.0 6.3 0.61 9.9 0.2 3.5 4 1 0 4 4 4 0 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.20 RLN74049.1 - 3.2e-11 43.4 0.0 4.5e-06 26.5 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN74049.1 - 0.0067 15.7 0.1 0.89 8.8 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 RLN74049.1 - 0.045 13.4 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 RLN74050.1 - 2e-15 57.2 0.0 5.9e-15 55.6 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN74050.1 - 8.2e-08 33.1 0.0 1.3e-07 32.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 RLN74050.1 - 0.023 14.8 0.0 0.047 13.8 0.0 1.5 1 1 0 1 1 1 0 TAP-like protein Hydrolase_4 PF12146.8 RLN74050.1 - 0.095 11.9 0.0 1.6 7.9 0.0 2.1 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN74052.1 - 1.3e-10 41.3 0.0 7.2e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN74052.1 - 8.8e-06 25.2 0.0 0.0019 17.5 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN74052.1 - 0.002 18.8 0.1 0.075 13.6 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 RLN74052.1 - 0.11 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family ABC_membrane PF00664.23 RLN74053.1 - 6.9e-54 183.3 3.1 8.9e-54 183.0 3.1 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region NDUF_B12 PF08122.12 RLN74053.1 - 5.8 7.0 6.2 4.5 7.4 0.9 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family CPSF_A PF03178.15 RLN74054.1 - 0.0055 16.1 0.0 0.017 14.4 0.0 1.8 1 1 1 2 2 2 1 CPSF A subunit region S_100 PF01023.19 RLN74055.1 - 0.017 14.8 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain DENN PF02141.21 RLN74057.1 - 7.1e-23 81.5 2.3 3.5e-15 56.4 0.3 2.6 2 1 1 3 3 3 2 DENN (AEX-3) domain SNARE_assoc PF09335.11 RLN74058.1 - 8.9e-19 68.2 8.7 8.9e-19 68.2 8.7 2.1 2 0 0 2 2 2 1 SNARE associated Golgi protein MFS_2 PF13347.6 RLN74059.1 - 2.6e-27 95.4 31.8 3.8e-22 78.4 6.9 2.4 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1 PF07690.16 RLN74059.1 - 5.4e-14 51.9 30.6 1.3e-07 30.8 14.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 RLN74059.1 - 1.3e-05 24.2 0.2 1.3e-05 24.2 0.2 2.1 2 0 0 2 2 2 1 LacY proton/sugar symporter Abhydrolase_1 PF00561.20 RLN74060.1 - 9.2e-21 74.6 0.0 3.3e-17 63.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN74060.1 - 4.5e-11 43.8 0.2 9e-11 42.8 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN74060.1 - 1.3e-10 41.0 0.0 3.7e-07 29.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 RLN74060.1 - 0.026 14.1 0.0 0.079 12.5 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family rRNA_proc-arch PF13234.6 RLN74061.1 - 1.9e-67 228.1 1.3 3.5e-67 227.2 1.3 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 RLN74061.1 - 3.8e-50 169.8 0.6 3.8e-50 169.8 0.6 2.1 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 RLN74061.1 - 2.8e-18 66.3 0.0 1.1e-17 64.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN74061.1 - 8e-07 29.4 0.2 3.6e-05 24.1 0.0 3.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain FBPase_3 PF01950.16 RLN74061.1 - 0.04 13.1 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 Fructose-1,6-bisphosphatase ATPase_2 PF01637.18 RLN74061.1 - 0.062 13.2 0.9 0.31 10.9 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Abhydrolase_1 PF00561.20 RLN74062.1 - 1.5e-44 152.6 0.2 5.5e-20 72.1 0.0 4.1 3 1 0 3 3 3 3 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN74062.1 - 4.4e-30 105.9 3.1 1.9e-17 64.6 0.1 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN74062.1 - 1.1e-23 83.8 1.2 6.7e-11 41.9 0.3 3.2 2 2 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 RLN74062.1 - 4.3e-09 36.2 0.3 0.0033 17.0 0.0 4.9 3 1 2 5 5 5 2 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 RLN74062.1 - 9.6e-09 35.3 0.0 0.00038 20.5 0.0 2.7 2 0 0 2 2 2 2 TAP-like protein Esterase PF00756.20 RLN74062.1 - 3.1e-07 30.3 0.1 0.0018 17.9 0.0 2.7 3 0 0 3 3 3 2 Putative esterase Thioesterase PF00975.20 RLN74062.1 - 4e-07 30.4 0.4 0.00049 20.3 0.0 2.8 3 0 0 3 3 3 2 Thioesterase domain Abhydrolase_3 PF07859.13 RLN74062.1 - 7.3e-06 26.0 0.1 0.092 12.6 0.0 3.0 2 2 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 RLN74062.1 - 3.1e-05 23.9 0.0 1.1 9.0 0.0 3.3 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 RLN74062.1 - 0.00018 21.3 0.0 0.17 11.6 0.0 3.6 4 0 0 4 4 4 1 Alpha/beta hydrolase family FSH1 PF03959.13 RLN74062.1 - 0.00023 20.9 0.1 2.1 8.0 0.0 3.4 3 0 0 3 3 3 2 Serine hydrolase (FSH1) LIP PF03583.14 RLN74062.1 - 0.00037 19.9 0.0 1.3 8.2 0.0 2.8 3 0 0 3 3 3 2 Secretory lipase Peptidase_S9 PF00326.21 RLN74062.1 - 0.0006 19.4 1.0 0.11 11.9 0.0 3.6 4 0 0 4 4 4 1 Prolyl oligopeptidase family Ndr PF03096.14 RLN74062.1 - 0.0041 15.9 0.0 0.85 8.3 0.0 2.4 3 0 0 3 3 3 2 Ndr family PGAP1 PF07819.13 RLN74062.1 - 0.0045 16.7 0.4 3.8 7.2 0.2 3.6 4 0 0 4 4 4 1 PGAP1-like protein BAAT_C PF08840.11 RLN74062.1 - 0.014 15.3 1.5 1.9 8.3 0.0 3.6 3 1 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 RLN74063.1 - 3.3e-16 59.7 0.0 6.2e-14 52.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN74063.1 - 1.2e-12 47.7 0.1 1.7e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN74063.1 - 2.6e-12 47.8 0.1 3.7e-12 47.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 RLN74063.1 - 0.00082 19.0 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 RLN74063.1 - 0.12 11.8 0.4 0.48 9.9 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 RLN74064.1 - 0.12 12.9 0.0 0.13 12.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family CDC45 PF02724.14 RLN74070.1 - 0.31 9.3 3.6 0.34 9.2 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RLN74070.1 - 3.5 5.7 9.8 3.8 5.6 9.8 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 RLN74070.1 - 9.3 5.5 11.4 11 5.2 11.4 1.0 1 0 0 1 1 1 0 BUD22 PHD PF00628.29 RLN74080.1 - 0.0038 17.1 5.7 0.0038 17.1 5.7 3.5 3 1 0 3 3 3 1 PHD-finger Glyco_hydro_81 PF03639.13 RLN74088.1 - 6.8e-50 170.0 2.1 8.8e-50 169.7 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Sugar_tr PF00083.24 RLN74093.1 - 1.2e-87 294.7 18.4 1.5e-87 294.4 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN74093.1 - 6.6e-27 94.4 30.1 2.4e-25 89.2 24.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GWT1 PF06423.12 RLN74093.1 - 0.0079 16.3 0.8 0.04 14.0 0.0 2.5 2 0 0 2 2 2 1 GWT1 TRI12 PF06609.13 RLN74093.1 - 0.19 10.1 14.2 0.0054 15.2 6.6 1.8 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 RLN74094.1 - 7e-37 127.4 20.3 7.7e-35 120.6 20.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN74094.1 - 4.1e-36 124.6 42.3 9.4e-32 110.3 24.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily RNase_H PF00075.24 RLN74102.1 - 1.4e-24 86.9 0.3 1.8e-24 86.5 0.3 1.1 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 RLN74102.1 - 2.2e-11 43.9 0.0 4.7e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF1706 PF08020.11 RLN74102.1 - 0.024 14.5 0.1 0.058 13.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) RVT_3 PF13456.6 RLN74102.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like Collar PF07484.12 RLN74102.1 - 0.1 12.6 0.1 0.99 9.5 0.0 2.2 2 0 0 2 2 2 0 Phage Tail Collar Domain Methyltr_RsmB-F PF01189.17 RLN74103.1 - 8.7e-39 133.2 0.0 3.7e-20 72.4 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F PUA PF01472.20 RLN74103.1 - 2.4e-07 30.6 0.2 7e-07 29.1 0.1 1.8 2 0 0 2 2 2 1 PUA domain Fibrillarin PF01269.17 RLN74103.1 - 0.0015 17.7 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin FtsJ PF01728.19 RLN74103.1 - 0.0028 17.8 0.0 0.013 15.6 0.0 1.9 1 1 0 1 1 1 1 FtsJ-like methyltransferase RNase_H PF00075.24 RLN74104.1 - 1.7e-23 83.4 0.3 1.7e-23 83.4 0.3 1.5 2 0 0 2 2 2 1 RNase H Cauli_VI PF01693.16 RLN74104.1 - 2e-10 40.8 0.0 3.6e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF1706 PF08020.11 RLN74104.1 - 0.036 14.0 0.2 0.064 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) PARP_reg PF02877.14 RLN74104.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain Collar PF07484.12 RLN74104.1 - 0.12 12.4 0.2 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Phage Tail Collar Domain RNase_H PF00075.24 RLN74105.1 - 1.3e-13 51.4 0.3 1.5e-13 51.1 0.3 1.1 1 0 0 1 1 1 1 RNase H DUF1706 PF08020.11 RLN74105.1 - 0.011 15.7 0.5 0.017 15.1 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) Pirin PF02678.16 RLN74106.1 - 1.4e-24 86.1 0.1 4.2e-24 84.6 0.1 1.8 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 RLN74106.1 - 6.4e-17 61.8 0.1 1.5e-16 60.6 0.0 1.6 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin_C_2 PF17954.1 RLN74106.1 - 0.059 13.6 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain UPF0160 PF03690.13 RLN74107.1 - 1.2e-127 426.0 0.0 1.4e-127 425.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) GTP_CH_N PF12471.8 RLN74107.1 - 0.022 14.5 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal Formin_GBD_N PF18382.1 RLN74107.1 - 0.15 12.6 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 Formin N-terminal GTPase-binding domain Aa_trans PF01490.18 RLN74114.1 - 1.1e-60 205.5 27.2 1.3e-60 205.3 27.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1240 PF06836.12 RLN74114.1 - 0.093 13.3 7.9 0.17 12.4 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) Aconitase PF00330.20 RLN74115.1 - 5.4e-70 236.7 0.2 3.5e-68 230.7 0.2 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 RLN74115.1 - 3.9e-17 62.8 0.0 7.5e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain FLYWCH_u PF16662.5 RLN74116.1 - 0.0073 16.3 0.2 0.029 14.4 0.2 2.0 1 0 0 1 1 1 1 FLYWCH-type zinc finger-containing protein 1 AAA_18 PF13238.6 RLN74117.1 - 2.6e-16 60.3 0.1 4.1e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 RLN74117.1 - 0.041 13.7 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase MIP PF00230.20 RLN74120.1 - 1.3e-49 168.9 11.5 1.3e-49 168.9 11.5 1.7 2 0 0 2 2 2 1 Major intrinsic protein NQR2_RnfD_RnfE PF03116.15 RLN74120.1 - 0.0019 17.6 2.1 0.0019 17.6 2.1 1.5 1 1 0 1 1 1 1 NQR2, RnfD, RnfE family RabGAP-TBC PF00566.18 RLN74124.1 - 6.2e-22 78.3 0.0 1.3e-21 77.2 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CH PF00307.31 RLN74124.1 - 0.051 13.8 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Calponin homology (CH) domain Kinesin PF00225.23 RLN74125.1 - 8.6e-86 287.9 0.0 2.4e-85 286.4 0.0 1.9 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN74125.1 - 5.1e-13 49.2 0.1 8e-08 32.4 0.4 2.8 1 1 1 2 2 2 2 Microtubule binding DUF4426 PF14467.6 RLN74125.1 - 4 7.4 5.8 1.7 8.6 0.3 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4426) RCC1 PF00415.18 RLN74126.1 - 5.3e-31 107.0 6.0 2.1e-07 31.5 0.2 4.3 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN74126.1 - 1.3e-22 79.0 13.0 1.9e-09 37.0 0.2 4.3 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat PapC_C PF13953.6 RLN74126.1 - 0.12 12.2 1.0 1.4 8.8 0.1 3.0 3 1 1 4 4 4 0 PapC C-terminal domain Caskin1-CID PF16600.5 RLN74141.1 - 2.2 8.9 7.0 13 6.5 7.0 2.3 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain Gp_dh_N PF00044.24 RLN74142.1 - 6.7e-19 68.1 0.0 1.9e-18 66.6 0.0 1.8 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain P34-Arc PF04045.14 RLN74142.1 - 0.17 11.5 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Arp2/3 complex, 34 kD subunit p34-Arc DMRL_synthase PF00885.19 RLN74143.1 - 1.4e-18 67.1 0.0 1.8e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase PT-VENN PF04829.13 RLN74148.1 - 0.026 14.6 0.6 0.054 13.6 0.6 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Ion_trans PF00520.31 RLN74167.1 - 1.7e-11 43.8 0.7 2.4e-08 33.5 0.2 2.2 2 0 0 2 2 2 2 Ion transport protein cNMP_binding PF00027.29 RLN74167.1 - 3.4e-11 43.1 0.0 6.9e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 RLN74167.1 - 0.0051 16.7 0.5 0.012 15.6 0.5 1.7 1 0 0 1 1 1 1 Ion channel MMR_HSR1 PF01926.23 RLN74171.1 - 3.5e-09 36.7 0.0 9.3e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 RLN74171.1 - 7.5e-06 25.4 0.1 1.3e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 RLN74171.1 - 0.00035 20.5 0.3 0.0018 18.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 RLN74171.1 - 0.00082 19.9 0.7 0.0033 18.0 0.0 2.2 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 RLN74171.1 - 0.011 16.1 0.4 0.03 14.7 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 RLN74171.1 - 0.022 14.5 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 RLN74171.1 - 0.024 15.1 0.0 0.071 13.5 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 RLN74171.1 - 0.055 13.5 6.9 15 5.6 0.1 4.0 3 2 0 3 3 3 0 Dynamin family FeoB_N PF02421.18 RLN74171.1 - 0.059 12.9 0.2 0.19 11.3 0.0 2.0 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.6 RLN74171.1 - 0.11 12.7 1.8 1.1 9.5 0.1 3.1 3 2 0 4 4 4 0 AAA domain PRKG1_interact PF15898.5 RLN74171.1 - 0.13 13.2 0.3 0.13 13.2 0.3 2.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain AAA_25 PF13481.6 RLN74171.1 - 0.16 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain PHD PF00628.29 RLN74172.1 - 3.6e-33 113.2 126.5 3.7e-06 26.7 6.3 16.5 16 1 0 16 16 16 10 PHD-finger FYRN PF05964.14 RLN74172.1 - 2.1e-18 65.9 0.1 4.7e-18 64.8 0.1 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus Bromodomain PF00439.25 RLN74172.1 - 1.8e-16 59.9 0.2 6.9e-16 58.1 0.1 2.0 2 0 0 2 2 2 1 Bromodomain SET PF00856.28 RLN74172.1 - 2.7e-14 53.9 4.1 1e-13 52.0 0.0 4.2 2 1 0 2 2 2 1 SET domain zf-HC5HC2H PF13771.6 RLN74172.1 - 8.4e-07 29.2 5.8 8.4e-07 29.2 5.8 9.6 9 1 0 9 9 9 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 RLN74172.1 - 3.4e-06 27.2 7.9 3.4e-06 27.2 7.9 7.9 8 0 0 8 8 8 2 PHD-zinc-finger like domain FYRC PF05965.14 RLN74172.1 - 0.00011 22.3 0.0 0.0014 18.8 0.0 2.9 2 1 0 2 2 2 1 F/Y rich C-terminus Pkinase_Tyr PF07714.17 RLN74173.1 - 5.1e-42 144.0 0.0 7.5e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN74173.1 - 9.9e-35 120.2 0.0 1.6e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF1616 PF07760.11 RLN74173.1 - 0.016 14.6 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Pkinase PF00069.25 RLN74181.1 - 5.6e-36 124.3 0.0 8.6e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN74181.1 - 1.2e-21 77.1 0.0 2e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN74181.1 - 0.00013 20.9 0.1 0.00014 20.8 0.1 1.3 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN74181.1 - 0.048 13.0 0.1 0.074 12.4 0.1 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 RLN74181.1 - 0.053 13.4 0.3 0.12 12.2 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 RLN74181.1 - 0.13 11.3 0.4 0.4 9.7 0.2 1.8 1 1 1 2 2 2 0 Seadornavirus VP7 Prominin PF05478.11 RLN74183.1 - 0.0017 16.4 0.2 0.0017 16.4 0.2 3.3 3 1 0 3 3 3 2 Prominin MIF PF01187.18 RLN74198.1 - 1.2e-11 44.9 0.1 1.4e-11 44.7 0.1 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 RLN74198.1 - 5e-08 32.8 0.1 9.9e-08 31.8 0.1 1.5 1 0 0 1 1 1 1 Tautomerase enzyme TrmB PF01978.19 RLN74198.1 - 0.14 12.1 0.7 0.52 10.2 0.1 2.1 2 1 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB ADH_N PF08240.12 RLN74199.1 - 4.8e-24 84.4 3.0 4.8e-24 84.4 3.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN74199.1 - 1.3e-13 51.1 0.0 2.3e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN74199.1 - 0.00029 20.2 0.0 0.00047 19.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN74199.1 - 0.0025 17.1 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 RLN74199.1 - 0.032 14.8 0.0 0.057 14.0 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 RLN74199.1 - 0.058 13.3 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_2 PF03446.15 RLN74199.1 - 0.073 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 RLN74199.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MMR_HSR1 PF01926.23 RLN74204.1 - 0.016 15.3 0.2 0.77 9.9 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC2_membrane PF01061.24 RLN74205.1 - 1.2e-64 217.6 72.4 7.6e-37 126.8 25.1 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN74205.1 - 5.5e-17 62.6 0.0 8.5e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN74205.1 - 5.2e-05 23.2 0.0 0.082 12.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system PDR_CDR PF06422.12 RLN74205.1 - 0.0033 17.3 0.0 0.0033 17.3 0.0 3.7 5 0 0 5 5 4 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 RLN74205.1 - 0.0033 16.6 42.1 0.0062 15.7 12.3 3.3 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_29 PF13555.6 RLN74205.1 - 0.0058 16.3 1.4 0.014 15.1 1.4 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN74205.1 - 0.0089 15.9 0.5 0.018 14.9 0.5 1.4 1 0 0 1 1 1 1 RsgA GTPase PDR_assoc PF08370.11 RLN74205.1 - 0.025 14.3 0.1 0.025 14.3 0.1 4.4 5 0 0 5 5 4 0 Plant PDR ABC transporter associated AAA_25 PF13481.6 RLN74205.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 RLN74205.1 - 0.099 12.1 1.5 0.58 9.6 0.2 2.7 2 2 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RLN74205.1 - 0.15 12.5 0.1 0.26 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain T2SSF PF00482.23 RLN74218.1 - 0.083 12.8 3.2 0.16 12.0 2.0 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F FYVE PF01363.21 RLN74219.1 - 0.15 12.2 8.2 0.34 11.1 8.2 1.6 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN74219.1 - 9.9 6.4 13.1 0.23 11.7 6.3 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger Dcc1 PF09724.9 RLN74220.1 - 6.8e-62 209.7 0.1 8.1e-62 209.4 0.1 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 PTS_2-RNA PF01885.16 RLN74221.1 - 4e-63 212.8 0.0 4.9e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Pkinase PF00069.25 RLN74223.1 - 1.8e-126 420.9 0.0 1.2e-64 218.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN74223.1 - 1.9e-49 168.3 0.0 3.3e-23 82.3 0.1 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase WW PF00397.26 RLN74223.1 - 2.9e-15 56.0 0.6 4.4e-07 29.9 0.1 2.5 2 0 0 2 2 2 2 WW domain Haspin_kinase PF12330.8 RLN74223.1 - 2.8e-09 36.4 0.2 7.3e-05 21.9 0.0 2.6 2 1 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 RLN74223.1 - 5.8e-08 33.0 0.3 0.01 15.8 0.0 3.0 2 1 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 RLN74223.1 - 5e-07 29.3 0.0 0.0066 15.8 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 RLN74223.1 - 3.8e-06 26.4 3.3 0.012 14.9 0.4 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RLN74223.1 - 0.02 14.5 0.1 8.5 5.9 0.0 2.5 3 0 0 3 3 3 0 Choline/ethanolamine kinase YukC PF10140.9 RLN74223.1 - 0.054 12.3 0.0 3.9 6.2 0.0 2.2 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC FTA2 PF13095.6 RLN74223.1 - 0.09 12.4 0.0 11 5.5 0.0 2.7 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 RLN74223.1 - 0.16 10.7 5.5 2.1 7.1 0.0 2.9 3 0 0 3 3 3 0 Fungal protein kinase zf-BED PF02892.15 RLN74224.1 - 0.001 19.0 0.1 0.0022 18.0 0.1 1.5 1 0 0 1 1 1 1 BED zinc finger DUF3046 PF11248.8 RLN74224.1 - 0.0036 17.6 0.0 0.0085 16.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3046) SRC-1 PF08832.10 RLN74224.1 - 0.9 10.6 5.4 1.2 10.2 0.0 3.2 2 1 0 2 2 2 0 Steroid receptor coactivator Pkinase PF00069.25 RLN74226.1 - 1.2e-35 123.1 0.0 1.2e-34 119.9 0.0 2.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN74226.1 - 3.7e-35 121.4 0.0 8.2e-35 120.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase RNase_H PF00075.24 RLN74228.1 - 7.9e-19 68.3 0.0 1.5e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 RLN74228.1 - 5.9e-10 39.3 0.6 1.3e-09 38.2 0.1 1.9 2 0 0 2 2 2 1 Caulimovirus viroplasmin SGT1 PF07093.11 RLN74229.1 - 1.4e-93 314.3 0.3 4.4e-74 250.0 0.0 2.1 1 1 1 2 2 2 2 SGT1 protein Kelch_4 PF13418.6 RLN74230.1 - 1.7e-21 76.0 0.1 2.5e-05 24.2 0.0 4.7 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 RLN74230.1 - 4.2e-18 65.2 16.8 1.4e-06 28.4 0.1 7.1 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN74230.1 - 3.1e-17 62.2 0.2 1.9e-06 27.7 0.1 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 RLN74230.1 - 2e-15 56.4 0.3 5.5e-07 29.6 0.1 4.7 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.25 RLN74230.1 - 2.2e-11 43.1 0.0 5.8e-06 25.8 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 RLN74230.1 - 1.6e-05 24.6 0.3 0.11 12.5 0.0 4.3 5 0 0 5 5 5 2 Kelch motif NUDIX PF00293.28 RLN74230.1 - 4.5e-05 23.5 0.2 0.00011 22.3 0.2 1.6 1 0 0 1 1 1 1 NUDIX domain DUF1676 PF07898.13 RLN74230.1 - 0.024 14.7 4.0 0.74 9.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Macoilin PF09726.9 RLN74230.1 - 2.6 6.5 12.0 5 5.6 12.0 1.4 1 0 0 1 1 1 0 Macoilin family adh_short PF00106.25 RLN74231.1 - 5.3e-29 101.1 0.6 4.9e-18 65.3 0.1 3.1 3 0 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 RLN74231.1 - 3e-15 56.4 0.4 3.3e-10 39.9 0.4 3.0 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN74231.1 - 3e-05 24.0 0.4 0.16 11.9 0.0 2.2 2 0 0 2 2 2 2 KR domain DUF4705 PF15788.5 RLN74231.1 - 0.037 14.3 0.0 0.096 12.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4705) Polysacc_synt_2 PF02719.15 RLN74231.1 - 0.087 11.9 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C2 PF00168.30 RLN74232.1 - 2.2e-18 66.5 0.0 4.4e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.17 RLN74232.1 - 0.0021 18.7 0.0 3.8 8.2 0.0 3.8 3 0 0 3 3 3 2 Putative heavy-metal-binding zinc_ribbon_4 PF13717.6 RLN74232.1 - 0.2 11.6 0.2 14 5.7 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain LRR_6 PF13516.6 RLN74233.1 - 1.2e-36 121.6 32.3 0.0018 18.2 0.0 15.5 17 0 0 17 17 17 11 Leucine Rich repeat LRR_1 PF00560.33 RLN74233.1 - 1.4e-06 28.0 11.7 97 4.2 0.1 12.4 14 2 0 14 14 14 0 Leucine Rich Repeat LRR_4 PF12799.7 RLN74233.1 - 0.0047 17.3 27.0 0.027 14.9 0.7 9.5 9 3 4 13 13 13 3 Leucine Rich repeats (2 copies) HHH_5 PF14520.6 RLN74233.1 - 0.056 14.1 0.1 1.9 9.1 0.0 3.2 3 0 0 3 3 3 0 Helix-hairpin-helix domain LRR_8 PF13855.6 RLN74233.1 - 0.09 12.6 26.3 0.084 12.6 0.9 8.1 7 2 2 9 9 9 0 Leucine rich repeat FumaraseC_C PF10415.9 RLN74233.1 - 0.33 11.4 2.4 7.5 7.0 0.0 3.7 4 0 0 4 4 4 0 Fumarase C C-terminus Pro_isomerase PF00160.21 RLN74234.1 - 0.00015 22.1 0.0 0.00017 21.9 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Adaptin_N PF01602.20 RLN74235.1 - 2e-151 505.1 12.6 2.7e-151 504.7 12.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 RLN74235.1 - 1e-66 224.0 8.5 1.3e-65 220.4 0.1 3.5 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 RLN74235.1 - 1.7e-24 86.1 0.3 6e-24 84.3 0.1 2.1 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 RLN74235.1 - 6e-18 65.0 4.8 6e-05 23.3 0.0 5.6 2 2 3 5 5 5 5 HEAT repeats HEAT PF02985.22 RLN74235.1 - 3.6e-11 42.3 4.8 0.0022 18.1 0.0 6.4 6 0 0 6 6 6 2 HEAT repeat Cnd3 PF12719.7 RLN74235.1 - 8e-08 31.8 1.7 4.1e-05 22.9 0.2 2.9 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 RLN74235.1 - 1.6e-06 27.9 1.0 0.018 15.0 0.0 4.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 RLN74235.1 - 9.6e-06 25.2 0.0 3.9e-05 23.2 0.0 2.1 1 0 0 1 1 1 1 Armadillo-like Alpha_adaptinC2 PF02883.20 RLN74235.1 - 3.4e-05 24.1 1.7 7.6e-05 23.0 1.7 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain UNC45-central PF11701.8 RLN74235.1 - 3.8e-05 23.7 1.2 0.1 12.5 0.0 3.9 3 1 0 3 3 3 2 Myosin-binding striated muscle assembly central DUF3157 PF11355.8 RLN74235.1 - 7.8e-05 22.4 1.8 0.00068 19.3 0.0 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF3157) CLASP_N PF12348.8 RLN74235.1 - 0.00089 18.9 3.4 1.2 8.6 0.0 3.8 2 2 1 3 3 3 2 CLASP N terminal RTP1_C1 PF10363.9 RLN74235.1 - 0.0011 19.1 4.0 2.1 8.6 0.0 4.8 2 2 2 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 RLN74235.1 - 0.0028 18.1 1.4 3.1 8.4 0.0 4.7 6 0 0 6 6 5 1 HEAT-like repeat DUF5578 PF17741.1 RLN74235.1 - 0.004 16.6 1.5 2.5 7.5 0.0 4.1 4 1 0 4 4 4 1 Family of unknown function (DUF5578) AP3B1_C PF14796.6 RLN74235.1 - 0.014 15.6 0.0 0.04 14.2 0.0 1.8 1 0 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal RasGEF_N_2 PF14663.6 RLN74235.1 - 0.2 12.0 1.6 23 5.4 0.0 4.2 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF3361 PF11841.8 RLN74235.1 - 1.5 8.7 4.9 22 5.0 0.0 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF3361) T2SSF PF00482.23 RLN74236.1 - 1.5e-05 25.0 0.0 0.078 12.9 0.0 2.4 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein F CAP_N PF01213.19 RLN74236.1 - 0.00037 20.1 6.0 0.011 15.2 1.0 2.5 2 0 0 2 2 2 2 Adenylate cyclase associated (CAP) N terminal Nsp1 PF11501.8 RLN74236.1 - 0.011 15.8 0.0 6.6 6.8 0.0 2.9 3 0 0 3 3 3 0 Non structural protein Nsp1 DUF5102 PF17104.5 RLN74236.1 - 0.015 15.3 0.0 4.7 7.2 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5102) FAR1 PF03101.15 RLN74236.1 - 0.028 15.1 0.3 0.028 15.1 0.3 2.6 2 1 0 2 2 2 0 FAR1 DNA-binding domain MetOD2 PF18548.1 RLN74236.1 - 0.031 14.4 0.0 7.4 6.8 0.0 2.8 2 0 0 2 2 2 0 Metanogen output domain 2 DUF3860 PF12976.7 RLN74236.1 - 0.095 12.7 0.0 24 5.0 0.0 2.7 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) MgtE_N PF03448.17 RLN74236.1 - 0.15 12.7 0.1 52 4.5 0.0 2.9 3 0 0 3 3 3 0 MgtE intracellular N domain REC1 PF18501.1 RLN74236.1 - 0.23 11.3 0.0 13 5.6 0.0 2.1 2 0 0 2 2 2 0 Alpha helical recognition lobe domain DivIC PF04977.15 RLN74237.1 - 0.1 12.4 3.1 2.6 7.9 0.2 2.3 1 1 1 2 2 2 0 Septum formation initiator CALM_bind PF16025.5 RLN74237.1 - 2.5 8.7 5.3 5.9 7.4 5.3 1.6 1 1 0 1 1 1 0 Calcium-dependent calmodulin binding Peptidase_M20 PF01546.28 RLN74238.1 - 6.2e-12 45.7 0.5 1.2e-10 41.5 0.5 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 RLN74238.1 - 4.7e-10 39.4 0.0 7.5e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 RLN74239.1 - 9.3e-08 32.0 0.0 9.4e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Pterin_4a PF01329.19 RLN74240.1 - 1.6e-25 89.1 0.0 2.4e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase RNA_pol_L_2 PF13656.6 RLN74241.1 - 1.6e-07 31.0 0.0 1.6e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 RLN74241.1 - 1.2e-05 24.7 0.0 9.3e-05 21.8 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain PX PF00787.24 RLN74242.1 - 3.3e-13 49.6 0.0 7.5e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 PX domain Lipase_3 PF01764.25 RLN74242.1 - 2.9e-11 43.4 0.0 8.1e-11 42.0 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) Peptidase_M20 PF01546.28 RLN74243.1 - 4.2e-21 75.6 0.0 5.9e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 RLN74243.1 - 3.2e-12 46.3 0.0 2e-11 43.8 0.0 2.3 2 1 0 2 2 2 1 Peptidase dimerisation domain Aldo_ket_red PF00248.21 RLN74244.1 - 5.8e-11 42.1 0.1 6.3e-11 42.0 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Rhodanese PF00581.20 RLN74245.1 - 1.9e-10 41.2 0.1 3.3e-10 40.4 0.1 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DUF3854 PF12965.7 RLN74245.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) Pkinase_Tyr PF07714.17 RLN74249.1 - 3.4e-25 88.8 0.0 5.8e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN74249.1 - 1e-24 87.3 0.0 2e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.23 RLN74249.1 - 1.1e-21 76.1 8.4 0.00029 20.8 0.0 9.7 10 0 0 10 10 10 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN74249.1 - 1.1e-08 35.4 17.0 0.014 15.9 0.2 6.1 6 0 0 6 6 6 3 HEAT-like repeat HEAT_2 PF13646.6 RLN74249.1 - 1.1e-05 25.7 27.1 0.0037 17.6 0.3 5.6 5 2 1 6 6 6 4 HEAT repeats Atx10homo_assoc PF09759.9 RLN74249.1 - 0.00018 21.5 0.1 9.1 6.4 0.0 4.8 5 0 0 5 5 5 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 RLN74249.1 - 0.002 18.2 7.1 14 6.2 0.0 7.6 8 0 0 8 8 8 1 HEAT repeat DUF4476 PF14771.6 RLN74249.1 - 0.096 13.0 0.1 0.26 11.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) Pkinase_fungal PF17667.1 RLN74249.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 RLN74253.1 - 7.6e-62 209.1 0.0 1.4e-61 208.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 RLN74253.1 - 7.2e-44 147.8 0.2 9.4e-22 76.9 0.0 2.9 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 RLN74253.1 - 8.3e-33 113.7 0.0 1.5e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN74253.1 - 8.5e-06 25.3 0.0 3.1e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 RLN74253.1 - 0.05 13.0 0.1 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Myosin_head PF00063.21 RLN74255.1 - 1.1e-208 694.8 2.0 1.1e-208 694.8 2.0 2.3 2 0 0 2 2 2 1 Myosin head (motor domain) AAA_16 PF13191.6 RLN74255.1 - 0.0071 16.7 0.1 0.052 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Borrelia_REV PF03978.13 RLN74255.1 - 0.013 15.5 2.3 0.61 10.0 0.7 3.4 2 1 0 2 2 2 0 Borrelia burgdorferi REV protein Myosin_N PF02736.19 RLN74255.1 - 0.058 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 RLN74255.1 - 0.63 10.3 4.7 0.66 10.2 0.0 3.5 5 0 0 5 5 5 0 AAA domain MatP_C PF17414.2 RLN74255.1 - 1.3 9.3 7.7 0.79 10.0 2.0 2.9 2 0 0 2 2 2 0 MatP C-terminal ribbon-helix-helix domain IQ PF00612.27 RLN74255.1 - 1.4 8.9 42.0 0.053 13.3 1.3 5.9 6 0 0 6 6 6 0 IQ calmodulin-binding motif XkdW PF09636.10 RLN74255.1 - 2 8.5 9.4 9.4 6.4 1.1 3.8 3 0 0 3 3 3 0 XkdW protein PX PF00787.24 RLN74256.1 - 2e-10 40.6 0.3 1.3e-09 38.0 0.0 2.2 2 1 0 2 2 2 1 PX domain Cystatin PF00031.21 RLN74257.1 - 7.1e-05 23.0 0.1 8.4e-05 22.8 0.1 1.3 1 1 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 RLN74257.1 - 0.0041 17.4 0.0 0.005 17.2 0.0 1.1 1 0 0 1 1 1 1 Aspartic acid proteinase inhibitor DAO_C PF16901.5 RLN74257.1 - 0.099 12.5 0.5 0.12 12.3 0.5 1.1 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase Ank_2 PF12796.7 RLN74258.1 - 2.5e-27 95.3 1.0 2.4e-10 40.9 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN74258.1 - 3.6e-24 84.8 2.7 2.8e-09 37.3 0.0 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN74258.1 - 1e-23 80.8 1.4 0.00021 21.5 0.2 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 RLN74258.1 - 1.8e-23 81.8 4.4 0.00023 21.5 0.1 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 RLN74258.1 - 6.5e-18 64.6 7.3 0.00048 20.4 0.2 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) U-box PF04564.15 RLN74258.1 - 2.5e-13 50.0 0.0 5.9e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 RLN74258.1 - 0.014 15.2 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Adenylsucc_synt PF00709.21 RLN74258.1 - 0.16 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Adenylosuccinate synthetase AAA_12 PF13087.6 RLN74259.1 - 1.3e-50 171.8 0.2 2.7e-50 170.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 RLN74259.1 - 9.8e-29 100.9 0.1 9.5e-15 55.1 0.1 2.7 1 1 1 2 2 2 2 AAA domain Dna2 PF08696.11 RLN74259.1 - 1.1e-24 87.5 0.0 1.5e-13 51.0 0.0 2.4 1 1 1 2 2 2 2 DNA replication factor Dna2 AAA_30 PF13604.6 RLN74259.1 - 9.4e-13 48.3 0.0 2.3e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RLN74259.1 - 7.7e-09 36.0 0.0 2.1e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 RLN74259.1 - 6.7e-06 26.0 0.2 0.04 13.7 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 RLN74259.1 - 0.00079 19.3 0.0 0.0022 17.8 0.0 1.8 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 RLN74259.1 - 0.019 14.8 0.0 0.05 13.4 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Thioredoxin_16 PF18569.1 RLN74259.1 - 0.039 14.1 0.0 2.4 8.3 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin-like domain UvrD-helicase PF00580.21 RLN74259.1 - 0.092 12.2 0.1 0.49 9.9 0.0 2.0 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain Glyco_hydro81C PF17652.1 RLN74260.1 - 1.1e-115 386.6 0.5 1.6e-115 386.1 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 RLN74260.1 - 1.1e-50 172.7 0.0 1.7e-50 172.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Histone PF00125.24 RLN74270.1 - 4.9e-36 124.0 1.1 4.9e-36 124.0 1.1 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 RLN74270.1 - 0.0033 17.5 0.0 0.0055 16.8 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 RLN74270.1 - 0.0063 16.7 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 RLN74270.1 - 0.02 15.2 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 RLN74270.1 - 0.06 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Ndc1_Nup PF09531.10 RLN74270.1 - 1.8 7.1 4.2 2.1 6.9 4.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SR-25 PF10500.9 RLN74270.1 - 4 7.0 7.4 6.8 6.2 7.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SGS PF05002.15 RLN74271.1 - 1.1e-26 92.7 3.8 1.1e-26 92.7 3.8 1.9 2 0 0 2 2 2 1 SGS domain CS PF04969.16 RLN74271.1 - 1.1e-15 58.4 0.2 2e-15 57.5 0.2 1.5 1 0 0 1 1 1 1 CS domain DUF3126 PF11324.8 RLN74271.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3126) TPR_1 PF00515.28 RLN74272.1 - 2.2e-08 33.6 13.1 0.0011 18.7 2.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN74272.1 - 8.5e-08 31.7 16.3 0.01 15.9 3.8 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN74272.1 - 2.2e-06 27.2 4.3 3e-06 26.8 2.1 2.3 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 RLN74272.1 - 2e-05 24.6 1.1 5.3e-05 23.3 1.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN74272.1 - 0.0011 19.6 13.3 0.0011 19.6 13.3 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN74272.1 - 0.0069 16.5 11.7 0.11 12.7 11.7 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN74272.1 - 0.024 15.1 13.3 0.099 13.2 9.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 RLN74272.1 - 0.94 9.9 9.2 6.2 7.3 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN74272.1 - 4.7 8.3 16.9 6.1 8.0 0.9 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat MMR_HSR1 PF01926.23 RLN74273.1 - 1.1e-18 67.4 0.1 1.8e-18 66.6 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RLN74273.1 - 5.7e-08 32.5 0.3 1.5e-06 27.9 0.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 RLN74273.1 - 1.6e-07 31.0 0.4 5.4e-07 29.3 0.4 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 RLN74273.1 - 2.1e-07 31.1 0.9 0.014 15.5 0.1 2.4 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 RLN74273.1 - 8.6e-06 25.8 1.8 0.022 14.6 0.9 2.7 2 1 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 RLN74273.1 - 1.2e-05 24.8 0.2 1.8e-05 24.2 0.2 1.3 1 0 0 1 1 1 1 AIG1 family ATP_bind_1 PF03029.17 RLN74273.1 - 0.00011 22.1 0.4 0.0004 20.2 0.2 1.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein cobW PF02492.19 RLN74273.1 - 0.00063 19.4 0.2 0.0011 18.6 0.2 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 RLN74273.1 - 0.005 16.3 0.5 0.016 14.7 0.5 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family TniB PF05621.11 RLN74273.1 - 0.014 14.8 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 RLN74273.1 - 0.017 15.3 0.0 0.041 14.1 0.0 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RLN74275.1 - 5e-38 130.3 2.2 1.4e-33 115.8 0.4 3.1 2 1 0 2 2 2 2 Ras family Roc PF08477.13 RLN74275.1 - 1.3e-19 70.5 2.6 2.7e-15 56.6 0.1 3.6 3 1 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN74275.1 - 1.5e-09 37.6 0.5 5.3e-08 32.5 0.5 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RLN74275.1 - 0.012 15.2 2.1 0.05 13.1 0.2 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PAS PF00989.25 RLN74276.1 - 1.3e-41 141.2 0.0 2.5e-14 53.2 0.0 3.2 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.7 RLN74276.1 - 8.4e-25 87.0 0.0 7.5e-10 39.0 0.0 3.2 3 0 0 3 3 3 3 PAS domain PAS_4 PF08448.10 RLN74276.1 - 4.5e-23 81.6 1.7 2.5e-09 37.3 0.1 3.3 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.7 RLN74276.1 - 3.2e-15 55.8 0.1 1.1e-06 28.5 0.0 3.3 3 0 0 3 3 3 3 PAS domain PAS_7 PF12860.7 RLN74276.1 - 3.4e-08 33.7 0.0 0.07 13.3 0.0 3.9 4 0 0 4 4 4 2 PAS fold PAS_3 PF08447.12 RLN74276.1 - 1.1e-07 32.1 0.0 0.0049 17.1 0.0 2.9 3 0 0 3 3 3 2 PAS fold PAS_10 PF13596.6 RLN74276.1 - 7.5e-06 26.5 0.0 0.22 12.1 0.0 3.2 3 0 0 3 3 3 2 PAS domain PAS_11 PF14598.6 RLN74276.1 - 0.0014 18.8 0.0 1.9 8.6 0.0 2.7 3 0 0 3 3 3 2 PAS domain MLTR_LBD PF17765.1 RLN74276.1 - 0.01 16.0 0.5 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain Ras PF00071.22 RLN74277.1 - 1.8e-40 138.2 0.0 2.1e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN74277.1 - 1.1e-24 86.9 0.0 1.5e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN74277.1 - 3.5e-10 39.6 0.0 4.8e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RLN74277.1 - 0.00028 20.9 0.0 0.0004 20.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RLN74277.1 - 0.0012 18.3 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 RLN74277.1 - 0.022 14.6 0.0 0.23 11.4 0.0 2.2 2 1 1 3 3 3 0 RsgA GTPase PAX PF00292.18 RLN74277.1 - 0.048 13.6 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain AAA_22 PF13401.6 RLN74277.1 - 0.082 13.2 0.0 0.12 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RLN74277.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2802 PF10975.8 RLN74278.1 - 0.12 12.5 1.7 0.2 11.8 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) zf-C3HC4_3 PF13920.6 RLN74279.1 - 0.00028 20.7 15.6 0.00045 20.0 15.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN74279.1 - 0.0052 17.1 15.0 0.0083 16.4 15.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN74279.1 - 0.0076 16.1 15.1 0.016 15.1 15.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN74279.1 - 0.0079 16.1 15.4 0.017 15.1 15.4 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RLN74279.1 - 0.026 14.4 14.0 0.054 13.4 14.0 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 RLN74279.1 - 0.037 13.8 12.2 0.079 12.8 12.2 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 RLN74279.1 - 0.28 11.1 15.4 0.46 10.4 15.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-WRNIP1_ubi PF18279.1 RLN74279.1 - 0.34 11.7 0.2 0.34 11.7 0.2 2.8 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain HECT PF00632.25 RLN74280.1 - 3.1e-38 132.0 0.0 4.5e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Nrap_D2 PF17403.2 RLN74280.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Ank_2 PF12796.7 RLN74282.1 - 2.4e-08 34.4 1.4 0.0027 18.2 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN74282.1 - 2.8e-07 30.3 5.3 0.0096 16.4 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 RLN74282.1 - 3.3e-07 30.5 2.6 0.00079 19.7 0.2 3.1 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN74282.1 - 1.8e-06 28.3 3.0 0.00014 22.4 0.1 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN74282.1 - 0.00029 21.2 5.9 0.051 14.0 0.1 4.2 4 1 0 4 4 4 2 Ankyrin repeat DUF4637 PF15470.6 RLN74282.1 - 0.003 17.3 0.8 0.0066 16.2 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4637) DENN PF02141.21 RLN74283.1 - 1.3e-37 129.5 0.1 3.2e-37 128.3 0.1 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain RGS PF00615.19 RLN74283.1 - 5.5e-12 46.0 0.0 7.5e-06 26.2 0.0 3.2 2 1 0 2 2 2 2 Regulator of G protein signaling domain dDENN PF03455.19 RLN74283.1 - 0.00028 20.8 0.4 0.00084 19.3 0.4 1.8 1 0 0 1 1 1 1 dDENN domain Avl9 PF09794.9 RLN74283.1 - 0.016 13.9 0.0 0.029 13.1 0.0 1.3 1 0 0 1 1 1 0 Transport protein Avl9 uDENN PF03456.18 RLN74283.1 - 0.016 16.0 0.1 0.06 14.1 0.1 1.9 1 0 0 1 1 1 0 uDENN domain PAS PF00989.25 RLN74284.1 - 2.6e-208 678.2 10.0 5.3e-23 81.2 0.0 11.1 11 0 0 11 11 11 10 PAS fold PAS_4 PF08448.10 RLN74284.1 - 2.4e-128 420.5 0.0 2.5e-13 50.3 0.0 11.3 11 0 0 11 11 11 10 PAS fold PAS_9 PF13426.7 RLN74284.1 - 2.2e-114 374.9 25.6 1.4e-11 44.6 0.0 11.2 11 0 0 11 11 11 10 PAS domain PAS_3 PF08447.12 RLN74284.1 - 3e-67 222.9 0.0 1.2e-05 25.5 0.0 10.4 10 0 0 10 10 10 10 PAS fold PAS_8 PF13188.7 RLN74284.1 - 1.6e-35 120.5 5.0 0.027 14.5 0.0 10.5 10 0 0 10 10 10 9 PAS domain HATPase_c PF02518.26 RLN74284.1 - 4.1e-25 88.5 0.0 1.4e-24 86.7 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_10 PF13596.6 RLN74284.1 - 1.6e-23 83.3 10.8 0.012 16.2 0.0 10.3 10 0 0 10 10 10 4 PAS domain Response_reg PF00072.24 RLN74284.1 - 2.9e-20 72.5 0.0 7.1e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 RLN74284.1 - 8.4e-17 61.0 0.0 2.5e-16 59.4 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Hpt PF01627.23 RLN74284.1 - 2.2e-08 34.2 1.2 8e-08 32.4 1.2 2.0 1 0 0 1 1 1 1 Hpt domain PAS_7 PF12860.7 RLN74284.1 - 1.3e-07 31.8 27.4 0.41 10.8 0.1 12.3 11 8 0 11 11 11 2 PAS fold DUF3189 PF11385.8 RLN74284.1 - 0.00013 21.9 0.2 45 3.9 0.0 5.8 6 0 0 6 6 6 0 Protein of unknown function (DUF3189) sCache_3_3 PF17202.4 RLN74284.1 - 0.0034 17.8 14.2 1.1e+02 3.2 0.0 9.3 12 0 0 12 12 9 0 Single cache domain 3 HlyD PF00529.20 RLN74284.1 - 0.02 14.7 0.7 42 4.1 0.0 5.2 6 0 0 6 6 6 0 HlyD membrane-fusion protein of T1SS Pilin_GH PF16734.5 RLN74284.1 - 0.083 13.2 0.0 33 4.8 0.0 4.2 5 0 0 5 5 4 0 Type IV pilin-like G and H, putative HATPase_c_3 PF13589.6 RLN74284.1 - 0.086 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GP79 PF17463.2 RLN74284.1 - 0.16 12.0 0.6 1.6e+02 2.4 0.0 4.7 4 0 0 4 4 4 0 Gene product 79 SAM_decarbox PF01536.16 RLN74296.1 - 2.6e-51 174.7 0.0 3e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase PRKCSH PF07915.13 RLN74297.1 - 7e-19 68.6 0.1 4.1e-14 53.4 0.1 2.3 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 RLN74297.1 - 2.7e-07 30.4 0.0 6.7e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Macoilin PF09726.9 RLN74302.1 - 0.018 13.6 13.4 0.0043 15.7 8.4 2.0 2 0 0 2 2 2 0 Macoilin family GIT_CC PF16559.5 RLN74302.1 - 0.029 14.2 1.1 0.029 14.2 1.1 4.2 3 1 2 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor TraC PF07820.12 RLN74302.1 - 0.036 14.4 2.4 0.11 12.9 0.4 2.9 2 0 0 2 2 2 0 TraC-like protein Cauli_AT PF03233.13 RLN74302.1 - 0.39 10.6 2.3 1.3 8.9 2.3 1.8 1 0 0 1 1 1 0 Aphid transmission protein DivIC PF04977.15 RLN74302.1 - 0.71 9.7 16.0 14 5.5 0.2 4.0 3 0 0 3 3 3 0 Septum formation initiator TPR_MLP1_2 PF07926.12 RLN74302.1 - 1.5 8.9 34.7 0.033 14.2 12.5 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.9 RLN74302.1 - 2.1 8.7 18.1 0.37 11.1 0.1 4.1 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AIP3 PF03915.13 RLN74302.1 - 2.2 7.3 17.2 0.04 13.0 9.4 1.9 2 0 0 2 2 2 0 Actin interacting protein 3 DUF5082 PF16888.5 RLN74302.1 - 2.2 8.6 16.2 0.82 10.0 0.6 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) Prominin PF05478.11 RLN74302.1 - 2.2 6.1 15.4 0.052 11.5 8.4 1.6 2 0 0 2 2 2 0 Prominin AAA_23 PF13476.6 RLN74302.1 - 2.4 8.6 9.9 13 6.2 5.1 2.8 2 1 0 2 2 2 0 AAA domain Golgin_A5 PF09787.9 RLN74302.1 - 2.6 7.4 31.0 1.1 8.7 3.6 3.0 2 1 1 3 3 3 0 Golgin subfamily A member 5 YabA PF06156.13 RLN74302.1 - 2.8 8.6 21.3 0.73 10.5 0.7 3.7 2 1 1 3 3 3 0 Initiation control protein YabA KASH_CCD PF14662.6 RLN74302.1 - 5.6 6.8 26.9 0.12 12.1 16.9 2.4 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 RLN74302.1 - 5.7 7.1 39.0 4.6 7.4 6.7 4.1 2 2 2 4 4 4 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 RLN74302.1 - 6 7.0 16.7 0.048 13.8 1.6 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.22 RLN74302.1 - 6.7 7.0 22.4 8.5 6.7 6.7 3.7 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FPP PF05911.11 RLN74302.1 - 7.4 4.6 26.6 0.32 9.2 17.1 2.7 2 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil TMF_DNA_bd PF12329.8 RLN74302.1 - 8.2 6.5 18.3 4.1 7.5 7.9 3.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding PAC1 PF16094.5 RLN74303.1 - 7.5e-09 35.1 0.0 9.6e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 HA2 PF04408.23 RLN74304.1 - 3e-14 53.2 0.0 3e-14 53.2 0.0 4.2 4 1 0 4 4 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 RLN74304.1 - 4e-13 49.7 0.1 9.7e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RLN74304.1 - 3.5e-08 33.4 0.0 9.2e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DND1_DSRM PF14709.7 RLN74304.1 - 0.00057 20.1 0.0 0.0022 18.2 0.0 2.1 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_19 PF13245.6 RLN74304.1 - 0.0011 19.3 0.1 0.0049 17.2 0.0 2.2 2 0 0 2 2 1 1 AAA domain OB_NTP_bind PF07717.16 RLN74304.1 - 0.0021 18.4 0.0 0.0091 16.3 0.0 2.2 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 RLN74304.1 - 0.0031 17.8 0.1 0.0031 17.8 0.1 3.2 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 RLN74304.1 - 0.013 14.5 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.15 RLN74304.1 - 0.034 14.1 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain FlxA PF14282.6 RLN74304.1 - 0.049 13.6 29.3 0.68 10.0 21.8 4.3 3 0 0 3 3 3 0 FlxA-like protein ATPase PF06745.13 RLN74304.1 - 0.055 12.8 0.0 0.16 11.3 0.0 1.8 1 0 0 1 1 1 0 KaiC dsRBD2 PF17842.1 RLN74304.1 - 0.086 13.0 2.2 0.15 12.3 0.0 2.4 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 ThrE PF06738.12 RLN74304.1 - 1.1 8.6 7.7 6 6.1 5.0 2.5 2 0 0 2 2 2 0 Putative threonine/serine exporter AAA_23 PF13476.6 RLN74304.1 - 2.4 8.6 0.0 2.4 8.6 0.0 3.5 3 1 0 3 3 2 0 AAA domain Aa_trans PF01490.18 RLN74308.1 - 6.2e-15 54.8 6.1 7.7e-15 54.5 6.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4018 PF13210.6 RLN74308.1 - 0.021 14.6 5.7 0.021 14.6 5.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4018) Flp1_like PF16982.5 RLN74308.1 - 0.037 13.4 1.0 0.083 12.3 1.0 1.5 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain TTL PF03133.15 RLN74309.1 - 6.6e-72 242.1 0.0 1e-71 241.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RLN74309.1 - 0.00011 21.6 0.0 0.00096 18.5 0.0 2.1 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RLN74309.1 - 0.0087 15.3 0.0 0.35 10.1 0.0 2.1 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp PDDEXK_3 PF13366.6 RLN74310.1 - 3.2e-30 104.9 0.0 5.1e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily HSDR_N_2 PF13588.6 RLN74310.1 - 0.041 13.9 0.0 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) SKIP_SNW PF02731.15 RLN74311.1 - 2e-71 238.8 3.0 2e-71 238.8 3.0 2.2 2 0 0 2 2 2 1 SKIP/SNW domain Cwf_Cwc_15 PF04889.12 RLN74311.1 - 0.0012 18.6 27.3 0.0012 18.6 27.3 2.4 3 0 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein DUF347 PF03988.12 RLN74312.1 - 5e-49 164.3 59.2 1.8e-14 53.7 4.8 6.5 6 1 0 6 6 6 4 Repeat of Unknown Function (DUF347) Got1 PF04178.12 RLN74312.1 - 7.7e-18 65.0 11.7 7.7e-18 65.0 11.7 4.3 4 2 1 6 6 6 2 Got1/Sft2-like family AA_permease PF00324.21 RLN74317.1 - 4e-14 52.1 31.4 5.8e-14 51.6 31.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 RLN74317.1 - 1.5e-12 47.1 36.0 1.9e-12 46.8 36.0 1.1 1 0 0 1 1 1 1 Amino acid permease Myb_DNA-binding PF00249.31 RLN74318.1 - 4.2e-28 97.3 5.2 7.5e-14 51.7 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN74318.1 - 3.9e-23 81.4 1.0 3.2e-14 52.9 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 RLN74318.1 - 0.0045 17.3 0.6 0.56 10.6 0.2 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like AXIN1_TNKS_BD PF16646.5 RLN74318.1 - 0.014 16.3 0.0 0.037 15.0 0.0 1.7 1 0 0 1 1 1 0 Axin-1 tankyrase binding domain Myb_DNA-bind_7 PF15963.5 RLN74318.1 - 0.094 12.6 0.0 0.33 10.9 0.0 1.8 1 1 1 2 2 2 0 Myb DNA-binding like SAS-6_N PF16531.5 RLN74338.1 - 1.2e-31 109.1 3.9 4.6e-31 107.3 0.0 2.5 2 0 0 2 2 2 1 Centriolar protein SAS N-terminal Jnk-SapK_ap_N PF09744.9 RLN74338.1 - 0.0089 16.3 18.2 0.0089 16.3 18.2 3.8 2 1 1 3 3 3 1 JNK_SAPK-associated protein-1 Gal-3-0_sulfotr PF06990.11 RLN74338.1 - 0.082 11.8 2.7 0.09 11.6 0.8 1.9 2 0 0 2 2 2 0 Galactose-3-O-sulfotransferase Gp-FAR-1 PF05823.12 RLN74338.1 - 0.24 11.7 18.7 0.98 9.8 4.7 3.4 1 1 2 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) BRE1 PF08647.11 RLN74338.1 - 0.66 10.1 36.3 0.071 13.2 12.8 4.7 2 1 3 5 5 5 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.10 RLN74338.1 - 1.4 9.1 26.1 1.6 8.9 3.8 3.4 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family TSC22 PF01166.18 RLN74338.1 - 5.1 7.5 9.8 0.86 10.0 3.3 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF3450 PF11932.8 RLN74338.1 - 5.9 6.1 39.5 0.017 14.4 16.7 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) YjcZ PF13990.6 RLN74338.1 - 9.4 5.5 18.3 0.28 10.5 9.4 2.1 1 1 1 2 2 2 0 YjcZ-like protein Lactamase_B_2 PF12706.7 RLN74351.1 - 1e-16 61.1 0.0 2e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 RLN74351.1 - 7e-07 28.8 0.1 2.4e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 tRNase Z endonuclease MRI PF15325.6 RLN74351.1 - 0.44 11.6 4.9 2.1 9.5 0.5 3.0 2 0 0 2 2 2 0 Modulator of retrovirus infection DivIVA PF05103.13 RLN74351.1 - 0.61 10.2 2.9 0.43 10.7 0.5 1.8 2 0 0 2 2 2 0 DivIVA protein Spt5_N PF11942.8 RLN74351.1 - 1.8 9.6 11.9 0.64 11.0 5.3 3.3 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Cwf_Cwc_15 PF04889.12 RLN74351.1 - 3.7 7.2 10.4 0.97 9.1 5.3 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RsbRD_N PF14361.6 RLN74352.1 - 0.06 14.0 0.2 0.076 13.7 0.2 1.3 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain Pkinase PF00069.25 RLN74353.1 - 7.4e-35 120.6 0.0 8.8e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN74353.1 - 1.5e-30 106.4 0.0 1.6e-30 106.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_6 PF13516.6 RLN74354.1 - 1.5e-06 27.8 21.8 0.0092 16.0 0.1 5.3 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 RLN74354.1 - 2.9e-05 24.3 15.6 0.00015 22.0 2.3 3.2 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN74354.1 - 0.032 14.7 6.0 7.9 7.5 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 RLN74354.1 - 3.1 7.6 18.0 0.13 12.0 2.0 4.4 2 2 1 4 4 4 0 Leucine rich repeat AAA_28 PF13521.6 RLN74355.1 - 0.0022 18.3 0.0 0.0037 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 RLN74356.1 - 1.9e-13 51.0 0.0 2.9e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 RLN74356.1 - 0.00013 21.0 0.0 0.00017 20.6 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 RLN74356.1 - 0.00085 18.9 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DAP3 PF10236.9 RLN74356.1 - 0.041 13.1 0.0 0.056 12.6 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_30 PF13604.6 RLN74356.1 - 0.055 13.2 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain QLQ PF08880.11 RLN74356.1 - 0.11 12.3 2.0 3.2 7.6 0.0 2.4 2 0 0 2 2 2 0 QLQ ATP_bind_1 PF03029.17 RLN74356.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 RLN74356.1 - 0.15 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 RLN74356.1 - 0.16 11.6 0.0 2.4 7.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain DDE_Tnp_1_7 PF13843.6 RLN74357.1 - 4.2e-37 128.3 0.0 2.5e-27 96.1 0.0 2.2 2 0 0 2 2 2 2 Transposase IS4 C1_2 PF03107.16 RLN74357.1 - 0.0039 17.5 1.6 0.008 16.5 1.6 1.5 1 0 0 1 1 1 1 C1 domain zf-HC5HC2H PF13771.6 RLN74357.1 - 0.011 16.0 2.3 0.024 14.9 2.3 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Zf_RING PF16744.5 RLN74357.1 - 0.055 13.6 0.5 0.16 12.1 0.5 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger C1_1 PF00130.22 RLN74357.1 - 0.44 10.5 4.2 1.1 9.2 4.2 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 RLN74357.1 - 2.1 8.3 8.0 0.075 12.9 1.8 1.8 2 0 0 2 2 2 0 PHD-finger NIF PF03031.18 RLN74358.1 - 7.6e-47 159.0 0.0 9.7e-47 158.6 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 RLN74358.1 - 0.0076 16.7 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Resolvase PF00239.21 RLN74358.1 - 0.038 14.1 0.7 0.093 12.8 0.0 1.9 3 0 0 3 3 3 0 Resolvase, N terminal domain Ras PF00071.22 RLN74360.1 - 4.3e-32 110.9 0.0 6e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN74360.1 - 2.4e-14 53.6 0.0 3.1e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 RLN74360.1 - 0.0097 16.0 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RLN74360.1 - 0.16 11.9 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Pkinase PF00069.25 RLN74361.1 - 6.3e-65 219.1 0.0 1.2e-64 218.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN74361.1 - 1.4e-41 142.6 0.0 3.7e-41 141.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Response_reg PF00072.24 RLN74361.1 - 1.9e-23 82.8 0.3 4.2e-23 81.7 0.3 1.6 1 0 0 1 1 1 1 Response regulator receiver domain DUF547 PF04784.14 RLN74361.1 - 2.3e-22 79.3 0.0 4.4e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Kinase-like PF14531.6 RLN74361.1 - 2.4e-05 23.8 0.0 4.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DEP PF00610.21 RLN74361.1 - 0.012 15.7 0.0 0.19 11.8 0.0 2.4 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pkinase_fungal PF17667.1 RLN74361.1 - 0.14 11.0 0.0 0.28 9.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase HTH_Tnp_Tc5 PF03221.16 RLN74372.1 - 5.2e-12 45.6 0.1 9e-12 44.8 0.1 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_Tnp_1 PF01527.20 RLN74372.1 - 0.002 18.4 0.3 0.53 10.6 0.1 3.2 3 0 0 3 3 3 1 Transposase HTH_32 PF13565.6 RLN74372.1 - 0.0032 18.0 1.8 0.02 15.5 0.6 2.4 2 0 0 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.13 RLN74372.1 - 0.0074 15.9 0.0 0.032 13.9 0.0 2.0 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_29 PF13551.6 RLN74372.1 - 0.0092 16.0 0.5 0.0092 16.0 0.5 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_11 PF08279.12 RLN74372.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_23 PF13384.6 RLN74372.1 - 0.018 14.8 0.3 0.1 12.4 0.3 2.3 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 RLN74372.1 - 0.019 14.4 0.1 0.091 12.2 0.0 2.2 2 1 1 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 RLN74372.1 - 0.06 13.5 0.3 0.06 13.5 0.3 2.8 3 1 0 3 3 3 0 Helix-turn-helix domain LZ_Tnp_IS66 PF13007.7 RLN74372.1 - 1.3 9.9 5.6 3.8 8.3 0.2 3.1 3 0 0 3 3 3 0 Transposase C of IS166 homeodomain UQ_con PF00179.26 RLN74373.1 - 2.5e-33 114.7 0.1 8.5e-32 109.7 0.1 2.5 2 1 0 2 2 2 1 Ubiquitin-conjugating enzyme AAA_11 PF13086.6 RLN74374.1 - 2e-62 211.3 0.8 2e-62 211.3 0.8 3.5 3 1 0 3 3 2 1 AAA domain AAA_12 PF13087.6 RLN74374.1 - 1.1e-52 178.6 0.0 2.1e-52 177.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RLN74374.1 - 2.3e-13 50.3 2.5 2.9e-12 46.7 0.1 3.4 2 2 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RLN74374.1 - 7.4e-09 36.1 2.3 5.9e-08 33.2 0.2 2.8 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 RLN74374.1 - 1.4e-08 34.8 4.4 1.2e-06 28.5 0.1 3.9 3 1 0 3 3 3 1 Helicase Viral_helicase1 PF01443.18 RLN74374.1 - 3.1e-08 33.7 0.2 0.32 10.7 0.0 3.5 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase zf-AN1 PF01428.16 RLN74374.1 - 4.4e-07 29.9 5.3 7.7e-07 29.2 5.3 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger ResIII PF04851.15 RLN74374.1 - 4.4e-06 26.8 0.0 2.6e-05 24.3 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RLN74374.1 - 4.2e-05 23.4 1.7 0.00047 20.0 0.0 2.6 1 1 0 2 2 2 1 DEAD/DEAH box helicase ATPase PF06745.13 RLN74374.1 - 0.00036 19.9 0.0 0.0011 18.3 0.0 1.8 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.6 RLN74374.1 - 0.00094 19.5 0.8 0.006 16.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 RLN74374.1 - 0.0017 18.7 0.0 0.01 16.2 0.0 2.5 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 RLN74374.1 - 0.0047 16.9 0.1 1.1 9.2 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 RLN74374.1 - 0.0065 16.9 0.0 0.028 14.8 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 RLN74374.1 - 0.012 15.0 0.0 0.044 13.2 0.0 1.9 1 0 0 1 1 1 0 PhoH-like protein Flavi_DEAD PF07652.14 RLN74374.1 - 0.013 15.5 0.9 0.15 12.0 0.0 2.6 2 1 0 2 2 2 0 Flavivirus DEAD domain NTPase_1 PF03266.15 RLN74374.1 - 0.016 15.1 3.1 1.6 8.6 0.1 2.6 2 0 0 2 2 2 0 NTPase UvrD_C PF13361.6 RLN74374.1 - 0.11 11.9 0.1 0.11 11.9 0.1 2.8 2 1 0 3 3 2 0 UvrD-like helicase C-terminal domain AAA_23 PF13476.6 RLN74374.1 - 0.19 12.2 0.0 0.19 12.2 0.0 3.3 3 1 0 3 3 3 0 AAA domain PA26 PF04636.13 RLN74374.1 - 0.4 9.5 3.2 0.88 8.4 3.2 1.5 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) UBX PF00789.20 RLN74375.1 - 1.1e-13 51.2 0.0 2.4e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 UBX domain MCD PF05292.11 RLN74375.1 - 0.021 14.4 2.0 0.034 13.7 2.0 1.4 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain Macoilin PF09726.9 RLN74375.1 - 0.023 13.3 3.1 0.025 13.2 3.1 1.1 1 0 0 1 1 1 0 Macoilin family DUF4746 PF15928.5 RLN74375.1 - 0.12 11.8 6.5 0.17 11.3 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2756 PF10956.8 RLN74375.1 - 0.76 10.3 3.9 1.3 9.6 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) Saw1 PF11561.8 RLN74375.1 - 0.96 8.9 6.1 0.54 9.8 4.0 1.6 2 0 0 2 2 2 0 Single strand annealing-weakened 1 CAF-1_p150 PF11600.8 RLN74375.1 - 1.1 8.9 20.6 1.6 8.4 20.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal ALMT PF11744.8 RLN74375.1 - 2.8 6.7 4.9 3.9 6.2 4.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Asp-B-Hydro_N PF05279.11 RLN74375.1 - 6.7 6.7 13.0 9.6 6.2 13.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Sua5_yciO_yrdC PF01300.18 RLN74376.1 - 4.3e-46 156.7 0.0 7.1e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 RLN74376.1 - 3.8e-18 66.4 0.3 5.4e-18 65.8 0.3 1.2 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Aa_trans PF01490.18 RLN74377.1 - 5.2e-27 94.6 7.6 6.2e-27 94.3 7.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 RLN74377.1 - 4.9e-06 25.8 5.9 9.3e-06 24.9 5.9 1.4 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DUF5134 PF17197.4 RLN74377.1 - 4.7 7.1 9.9 1.5 8.7 5.4 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5134) Glyco_hydro_1 PF00232.18 RLN74382.1 - 4.6e-124 414.3 0.0 6.2e-124 413.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 adh_short PF00106.25 RLN74382.1 - 2.8e-32 111.8 3.0 4.9e-32 111.0 3.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN74382.1 - 3.2e-26 92.3 1.0 7.1e-26 91.2 1.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MT-A70 PF05063.14 RLN74383.1 - 5e-34 117.7 0.1 7.5e-34 117.1 0.1 1.3 1 0 0 1 1 1 1 MT-A70 FlxA PF14282.6 RLN74390.1 - 0.018 15.0 1.9 0.052 13.5 1.9 1.7 1 0 0 1 1 1 0 FlxA-like protein TPR_9 PF13371.6 RLN74390.1 - 0.024 14.8 2.6 0.035 14.2 0.6 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2205 PF10224.9 RLN74391.1 - 0.069 13.2 0.1 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 Short coiled-coil protein DUF4322 PF14210.6 RLN74391.1 - 0.094 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4322) NMT1 PF09084.11 RLN74393.1 - 0.034 14.1 0.5 0.2 11.6 0.1 2.0 2 0 0 2 2 2 0 NMT1/THI5 like TBPIP PF07106.13 RLN74402.1 - 1.2e-18 66.8 0.3 3e-18 65.5 0.3 1.8 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain YL1 PF05764.13 RLN74402.1 - 1.6e-06 28.4 11.9 3.5e-06 27.3 11.9 1.5 1 0 0 1 1 1 1 YL1 nuclear protein LZ3wCH PF18517.1 RLN74402.1 - 0.00026 21.0 0.3 0.0011 19.1 0.0 2.3 2 0 0 2 2 2 1 Leucine zipper with capping helix domain TFIIF_alpha PF05793.12 RLN74402.1 - 0.0046 15.6 15.7 0.0078 14.9 15.7 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) APG6_N PF17675.1 RLN74402.1 - 0.0052 17.3 5.5 0.013 16.0 5.5 1.7 1 1 0 1 1 1 1 Apg6 coiled-coil region Nop14 PF04147.12 RLN74402.1 - 0.011 14.0 12.4 0.017 13.4 12.4 1.3 1 0 0 1 1 1 0 Nop14-like family DUF4600 PF15372.6 RLN74402.1 - 0.13 12.7 0.8 0.29 11.6 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) DivIC PF04977.15 RLN74402.1 - 0.13 12.0 2.9 0.15 11.9 1.1 2.0 1 1 1 2 2 2 0 Septum formation initiator ABC_tran_CTD PF16326.5 RLN74402.1 - 0.4 10.9 8.0 1.4 9.2 8.0 1.9 1 1 0 1 1 1 0 ABC transporter C-terminal domain DUF4140 PF13600.6 RLN74402.1 - 0.62 10.5 3.1 49 4.4 3.1 2.6 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DNA_pol_phi PF04931.13 RLN74402.1 - 1.1 7.3 20.4 7.3 4.5 20.8 1.9 2 0 0 2 2 2 0 DNA polymerase phi Osteopontin PF00865.18 RLN74402.1 - 3.9 6.9 23.8 6.5 6.2 23.8 1.3 1 0 0 1 1 1 0 Osteopontin SDA1 PF05285.12 RLN74402.1 - 5.8 6.2 17.5 11 5.4 17.5 1.4 1 0 0 1 1 1 0 SDA1 FAM220 PF15487.6 RLN74402.1 - 7.8 6.0 7.5 13 5.3 7.5 1.3 1 0 0 1 1 1 0 FAM220 family DUF4078 PF13300.6 RLN74409.1 - 3 8.2 18.1 0.97 9.8 6.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4078) 4HBT_2 PF13279.6 RLN74413.1 - 5.3e-23 81.8 0.0 6.5e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily SEN1_N PF12726.7 RLN74414.1 - 1.7e-06 26.6 0.9 0.0012 17.2 0.0 2.1 2 0 0 2 2 2 2 SEN1 N terminal NDC10_II PF16787.5 RLN74418.1 - 8.1e-65 218.9 0.0 1.1e-64 218.6 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 RLN74418.1 - 1.6e-17 63.6 0.0 4.6e-17 62.1 0.0 1.8 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes WD40 PF00400.32 RLN74419.1 - 2.6e-38 129.3 16.8 2.5e-08 34.4 1.6 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.11 RLN74419.1 - 0.00018 20.4 0.2 0.38 9.4 0.0 2.9 1 1 2 3 3 3 2 Nup133 N terminal like SAP PF02037.27 RLN74421.1 - 1.1e-13 50.6 0.9 1.4e-13 50.2 0.9 1.2 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 RLN74421.1 - 0.0035 17.0 0.1 0.0051 16.5 0.1 1.4 1 1 0 1 1 1 1 HeH/LEM domain HAD_2 PF13419.6 RLN74423.1 - 5.5e-10 39.6 0.0 3.1e-09 37.2 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RLN74423.1 - 6.5e-09 35.7 0.2 1.4e-08 34.7 0.2 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 RLN74423.1 - 1.5e-07 31.9 0.0 2.9e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_26 PF13500.6 RLN74424.1 - 2.9e-45 154.5 0.0 5.3e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DRTGG PF07085.12 RLN74424.1 - 7.8e-09 35.3 0.0 1.7e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 DRTGG domain CbiA PF01656.23 RLN74424.1 - 0.028 14.5 0.2 0.37 10.8 0.2 2.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PRORP PF16953.5 RLN74425.1 - 5.1e-11 42.6 8.6 1.6e-09 37.6 0.9 4.3 3 1 0 3 3 3 2 Protein-only RNase P PPR_long PF17177.4 RLN74425.1 - 0.0011 18.4 0.0 0.0038 16.6 0.0 1.8 1 1 1 2 2 2 1 Pentacotripeptide-repeat region of PRORP RNase_Zc3h12a PF11977.8 RLN74425.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain PH PF00169.29 RLN74426.1 - 0.0006 20.3 0.0 0.0013 19.2 0.0 1.7 1 1 0 1 1 1 1 PH domain DCB PF16213.5 RLN74427.1 - 4.8e-27 94.8 2.2 7.7e-26 90.8 2.2 2.2 1 1 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 RLN74427.1 - 1.4e-07 31.6 0.0 2.6e-06 27.4 0.0 2.5 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Lant_dehydr_C PF14028.6 RLN74427.1 - 0.006 16.2 1.1 0.39 10.2 0.4 2.2 2 0 0 2 2 2 2 Lantibiotic biosynthesis dehydratase C-term MULE PF10551.9 RLN74444.1 - 3.5e-05 24.1 0.3 0.00015 22.1 0.0 2.2 2 0 0 2 2 2 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 RLN74444.1 - 0.0035 17.1 1.1 0.0035 17.1 1.1 2.3 2 1 0 2 2 2 1 Transposase Put_Phosphatase PF06888.12 RLN74445.1 - 9.5e-142 470.3 0.0 7.5e-54 182.6 0.0 4.0 3 1 1 4 4 4 4 Putative Phosphatase HAD PF12710.7 RLN74445.1 - 7.7e-17 62.3 0.4 2.2e-05 25.0 0.0 3.8 3 2 0 3 3 3 3 haloacid dehalogenase-like hydrolase WCCH PF03716.14 RLN74445.1 - 0.034 13.8 0.8 0.077 12.7 0.8 1.6 1 0 0 1 1 1 0 WCCH motif Acid_PPase PF12689.7 RLN74445.1 - 0.14 12.0 2.0 25 4.7 0.0 3.3 3 1 1 4 4 4 0 Acid Phosphatase Glycos_transf_2 PF00535.26 RLN74447.1 - 1.1e-25 90.3 0.1 1.5e-25 90.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 RLN74447.1 - 4.4e-11 43.1 0.1 6.2e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 RLN74447.1 - 4.3e-07 29.7 0.0 6.4e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 SBD_N PF07005.11 RLN74447.1 - 0.00024 20.9 0.2 0.00041 20.2 0.2 1.3 1 0 0 1 1 1 1 Sugar-binding N-terminal domain IL10 PF00726.17 RLN74448.1 - 0.096 12.2 0.0 0.2 11.2 0.0 1.4 1 1 0 1 1 1 0 Interleukin 10 Ank_2 PF12796.7 RLN74449.1 - 4.9e-46 155.2 4.5 6.4e-18 65.1 0.0 6.3 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN74449.1 - 3.5e-39 128.3 1.9 1.6e-05 24.9 0.0 9.8 9 1 1 10 10 10 7 Ankyrin repeat Ank_4 PF13637.6 RLN74449.1 - 1.3e-33 114.9 1.6 9.9e-11 42.0 0.0 8.6 4 1 4 8 8 8 7 Ankyrin repeats (many copies) TIR_2 PF13676.6 RLN74449.1 - 7e-32 110.5 0.0 2e-17 63.9 0.0 2.6 2 0 0 2 2 2 2 TIR domain Ank PF00023.30 RLN74449.1 - 4.2e-31 106.0 5.6 4.8e-05 23.6 0.0 8.7 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 RLN74449.1 - 1.1e-27 95.8 6.0 8.3e-08 32.4 0.0 6.9 4 1 2 6 6 6 6 Ankyrin repeats (many copies) TIR PF01582.20 RLN74449.1 - 3.6e-09 36.7 0.0 0.0018 18.1 0.0 3.2 3 0 0 3 3 3 2 TIR domain DUF1863 PF08937.11 RLN74449.1 - 2e-06 28.2 0.0 0.026 14.9 0.0 2.9 2 1 0 2 2 2 2 MTH538 TIR-like domain (DUF1863) DUF3810 PF12725.7 RLN74449.1 - 0.0099 15.3 1.0 0.021 14.2 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3810) AMP-binding PF00501.28 RLN74450.1 - 2.2e-37 128.7 0.9 2.9e-36 125.0 0.9 2.2 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN74450.1 - 1.9e-05 25.6 0.1 5.8e-05 24.0 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DEK_C PF08766.11 RLN74451.1 - 3.9e-08 33.1 0.2 0.00046 20.1 0.1 2.5 2 0 0 2 2 2 2 DEK C terminal domain Apt1 PF10351.9 RLN74451.1 - 0.02 13.8 4.5 0.028 13.3 4.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain CC190 PF15768.5 RLN74451.1 - 0.023 14.8 9.8 0.044 13.8 9.8 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 BSP_II PF05432.11 RLN74451.1 - 0.28 10.8 21.1 0.59 9.8 21.1 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) BUD22 PF09073.10 RLN74451.1 - 0.48 9.7 24.3 0.73 9.1 24.3 1.2 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 RLN74451.1 - 2 7.1 8.5 3 6.5 8.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 RLN74451.1 - 5.7 5.1 12.9 7.4 4.7 12.9 1.2 1 0 0 1 1 1 0 CDC45-like protein CDC27 PF09507.10 RLN74451.1 - 7.8 5.8 27.8 0.24 10.8 21.8 1.5 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Glyco_transf_28 PF03033.20 RLN74452.1 - 0.00019 21.5 0.0 0.00024 21.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Maf PF02545.14 RLN74476.1 - 3.5e-42 144.1 0.0 3.7e-35 121.2 0.0 2.0 1 1 1 2 2 2 2 Maf-like protein MBOAT PF03062.19 RLN74477.1 - 9.7e-39 133.7 9.6 2.2e-38 132.5 9.5 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Sushi PF00084.20 RLN74478.1 - 2.1e-07 31.4 1.7 2.1e-07 31.4 1.7 2.7 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) HRM PF02793.22 RLN74478.1 - 0.011 16.0 0.3 0.011 16.0 0.3 2.4 2 0 0 2 2 2 0 Hormone receptor domain TPR_2 PF07719.17 RLN74479.1 - 2.7e-12 45.8 0.9 0.0017 18.4 0.1 4.0 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN74479.1 - 9.6e-11 41.2 0.0 0.0021 17.7 0.0 3.6 2 2 1 3 3 3 3 TPR repeat TPR_1 PF00515.28 RLN74479.1 - 2.8e-09 36.4 0.3 0.001 18.8 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN74479.1 - 1.5e-08 34.2 0.0 0.035 14.3 0.0 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN74479.1 - 2.2e-08 34.2 13.6 0.00044 20.8 0.2 4.3 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 RLN74479.1 - 5.6e-08 32.6 0.0 0.028 14.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN74479.1 - 7.8e-08 32.8 12.8 5.2e-05 23.8 3.0 3.1 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN74479.1 - 3.8e-07 30.3 8.0 0.0021 18.3 2.2 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN74479.1 - 1.3e-05 25.6 6.9 0.01 16.3 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN74479.1 - 4.8e-05 23.1 7.7 0.0061 16.5 0.1 3.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN74479.1 - 0.00028 20.7 2.9 0.17 11.8 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 RLN74479.1 - 0.0039 17.7 9.2 0.12 13.0 0.1 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN74479.1 - 0.0095 16.1 0.0 0.75 10.1 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Suf PF05843.14 RLN74479.1 - 0.13 12.2 0.1 0.14 12.1 0.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TPR_9 PF13371.6 RLN74479.1 - 0.27 11.4 11.3 0.99 9.6 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 RLN74479.1 - 2.5 8.5 7.4 12 6.3 0.0 3.2 2 1 0 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.7 RLN74480.1 - 8.1e-09 36.0 0.2 2.2e-08 34.6 0.2 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN74480.1 - 3.5e-06 27.2 2.6 0.1 13.0 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN74480.1 - 1.6e-05 25.3 1.0 0.00011 22.6 0.3 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN74480.1 - 0.00069 19.9 2.6 2 9.2 0.1 4.2 4 0 0 4 4 4 1 Ankyrin repeat NARP1 PF12569.8 RLN74480.1 - 1.7 7.4 8.6 3.3 6.5 8.6 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_M3_N PF08439.10 RLN74481.1 - 0.16 12.3 0.2 0.33 11.3 0.2 1.4 1 0 0 1 1 1 0 Oligopeptidase F PX PF00787.24 RLN74482.1 - 1.9e-08 34.3 0.5 7.9e-08 32.3 0.1 2.3 2 0 0 2 2 2 1 PX domain Metallophos PF00149.28 RLN74483.1 - 1.8e-14 54.8 0.0 2.3e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RLN74483.1 - 6.1e-08 33.0 0.0 9.7e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 RLN74483.1 - 0.02 14.2 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily MBOAT PF03062.19 RLN74484.1 - 9.6e-40 137.0 1.2 1.9e-39 136.0 1.2 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family AAA_6 PF12774.7 RLN74485.1 - 1.1e-148 494.6 0.0 1.3e-146 487.8 0.0 3.2 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN74485.1 - 1.3e-135 452.6 4.3 3.2e-135 451.3 4.3 1.7 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RLN74485.1 - 6.2e-99 330.5 0.0 1.6e-98 329.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 RLN74485.1 - 2.5e-68 229.1 0.2 1.9e-63 213.2 0.0 4.3 4 1 0 4 4 4 1 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 RLN74485.1 - 8.7e-30 103.5 0.1 2.6e-29 101.9 0.1 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RLN74485.1 - 2.4e-18 66.2 0.0 1.8e-17 63.4 0.0 2.6 2 0 0 2 2 1 1 AAA+ lid domain MT PF12777.7 RLN74485.1 - 4.4e-17 62.1 10.0 7e-17 61.5 10.0 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 RLN74485.1 - 7.1e-13 48.7 0.2 0.014 15.4 0.0 5.6 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RLN74485.1 - 1.9e-11 44.4 0.3 0.0046 17.2 0.0 5.7 6 0 0 6 6 6 2 AAA domain AAA PF00004.29 RLN74485.1 - 6.6e-09 36.3 0.9 0.14 12.6 0.0 5.2 5 1 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN74485.1 - 1.3e-07 32.2 1.6 0.051 14.0 0.0 5.7 5 0 0 5 5 5 1 AAA ATPase domain AAA_18 PF13238.6 RLN74485.1 - 1.2e-05 25.9 1.6 0.051 14.1 0.0 4.6 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 RLN74485.1 - 0.001 18.8 3.4 2 8.1 0.1 4.2 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 RLN74485.1 - 0.0062 16.9 0.2 30 5.1 0.0 3.6 3 0 0 3 3 3 0 RNA helicase AAA_33 PF13671.6 RLN74485.1 - 0.01 16.0 0.9 28 4.9 0.0 4.2 4 0 0 4 4 4 0 AAA domain DUF2075 PF09848.9 RLN74485.1 - 0.012 14.9 0.1 0.035 13.4 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 RLN74485.1 - 0.015 15.3 0.2 7.7 6.5 0.1 2.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 RLN74485.1 - 0.029 14.4 0.1 1.9 8.5 0.0 3.3 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 RLN74485.1 - 0.031 14.3 3.6 29 4.7 0.0 4.3 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF853 PF05872.12 RLN74485.1 - 0.042 12.4 1.3 0.4 9.2 0.0 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) T2SSE PF00437.20 RLN74485.1 - 0.12 11.5 5.5 0.14 11.2 0.0 3.4 4 0 0 4 4 4 0 Type II/IV secretion system protein NACHT PF05729.12 RLN74485.1 - 0.15 11.9 0.9 1.4 8.8 0.0 3.0 3 0 0 3 3 3 0 NACHT domain AAA_28 PF13521.6 RLN74485.1 - 0.77 10.0 2.4 94 3.2 0.0 4.2 5 0 0 5 5 4 0 AAA domain ABC_tran PF00005.27 RLN74485.1 - 0.97 9.9 4.4 78 3.8 0.1 4.1 4 0 0 4 4 3 0 ABC transporter AAA_19 PF13245.6 RLN74485.1 - 4.4 7.6 10.1 1 9.7 0.1 4.7 5 0 0 5 5 5 0 AAA domain LNS2 PF08235.13 RLN74491.1 - 2.9e-36 125.0 0.0 4.7e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) HA PF03457.14 RLN74491.1 - 5.1e-17 61.9 1.2 6.3e-07 29.6 0.2 3.6 3 0 0 3 3 3 3 Helicase associated domain Pkinase_Tyr PF07714.17 RLN74492.1 - 7.1e-55 186.1 0.0 8.6e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN74492.1 - 2.7e-51 174.5 0.0 3.7e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain AraC_N PF06719.13 RLN74492.1 - 0.082 12.6 0.1 0.17 11.5 0.0 1.6 2 0 0 2 2 2 0 AraC-type transcriptional regulator N-terminus Malate_synthase PF01274.22 RLN74493.1 - 6.3e-204 678.1 0.0 7.2e-204 677.9 0.0 1.0 1 0 0 1 1 1 1 Malate synthase SPX PF03105.19 RLN74494.1 - 5.2e-25 89.2 13.9 2.1e-12 47.7 2.8 3.3 1 1 2 3 3 3 3 SPX domain WCCH PF03716.14 RLN74495.1 - 5.4 6.8 8.3 20 5.0 1.0 3.0 2 0 0 2 2 2 0 WCCH motif Ank_2 PF12796.7 RLN74497.1 - 8e-25 87.2 4.1 5.9e-13 49.2 0.2 3.5 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN74497.1 - 2.5e-23 82.1 0.9 2.3e-10 40.8 0.0 5.4 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN74497.1 - 8.5e-23 80.1 0.6 8.2e-09 35.6 0.1 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN74497.1 - 4.7e-20 71.1 4.0 5.9e-06 26.5 0.1 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 RLN74497.1 - 3.9e-18 63.7 2.6 0.00055 20.2 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat HECT PF00632.25 RLN74498.1 - 4e-40 138.2 0.0 5.5e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) tRNA_m1G_MT PF01746.21 RLN74499.1 - 5.8e-16 58.8 0.0 7.8e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase HemX PF04375.14 RLN74499.1 - 0.012 15.0 1.2 0.019 14.3 1.2 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase MAS20 PF02064.15 RLN74499.1 - 0.33 11.1 4.7 0.32 11.1 3.5 1.6 2 0 0 2 2 2 0 MAS20 protein import receptor DUF3824 PF12868.7 RLN74499.1 - 3.6 8.2 14.7 0.069 13.8 3.1 2.2 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) Drc1-Sld2 PF11719.8 RLN74503.1 - 0.026 14.1 7.3 0.037 13.6 7.3 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF4674 PF15719.5 RLN74503.1 - 2.6 8.0 5.2 0.52 10.3 1.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4674) PsbW PF07123.12 RLN74504.1 - 0.094 12.7 0.2 0.27 11.3 0.2 1.7 1 1 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) TFIIB PF00382.19 RLN74505.1 - 0.64 10.1 4.1 1.1 9.4 0.1 2.6 2 1 0 2 2 2 0 Transcription factor TFIIB repeat Sin_N PF04801.13 RLN74506.1 - 1.1e-44 153.4 2.1 1.4e-44 153.0 2.1 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region Sedlin_N PF04628.13 RLN74507.1 - 8.5e-40 135.9 0.0 9.3e-40 135.8 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 RLN74507.1 - 2.1e-13 50.4 0.0 3.2e-12 46.6 0.0 2.0 2 0 0 2 2 2 1 Sybindin-like family Ribosomal_S19e PF01090.19 RLN74508.1 - 1.2e-57 193.5 0.3 1.3e-57 193.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_12 PF08461.10 RLN74508.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Golgin_A5 PF09787.9 RLN74509.1 - 0.0006 19.4 20.8 0.014 14.9 0.3 3.3 3 1 0 3 3 3 2 Golgin subfamily A member 5 GRIP PF01465.20 RLN74509.1 - 0.00062 19.6 0.1 0.0024 17.7 0.1 2.1 2 0 0 2 2 2 1 GRIP domain Pedibin PF08182.11 RLN74509.1 - 5.4 6.9 8.5 1.2 9.0 0.3 2.8 2 0 0 2 2 2 0 Pedibin/Hym-346 family OmpH PF03938.14 RLN74509.1 - 6 7.2 14.0 1.5 9.1 0.1 2.8 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 RLN74509.1 - 8.3 5.7 13.5 0.76 9.1 5.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) FYVE PF01363.21 RLN74510.1 - 0.00014 21.9 6.5 0.00029 20.9 6.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger Prok-RING_2 PF14445.6 RLN74510.1 - 0.029 14.5 0.9 0.078 13.2 0.9 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 zf-B_box PF00643.24 RLN74510.1 - 2.2 8.5 7.4 1.6 8.9 4.9 1.9 1 1 1 2 2 2 0 B-box zinc finger DDE_3 PF13358.6 RLN74517.1 - 5.4e-11 42.4 0.3 1.3e-09 38.0 0.0 2.9 2 1 0 2 2 2 1 DDE superfamily endonuclease XylR_N PF06505.11 RLN74517.1 - 0.17 11.6 0.9 2.5 7.9 0.1 2.5 2 0 0 2 2 2 0 Activator of aromatic catabolism SARG PF15385.6 RLN74521.1 - 9.1 5.4 9.4 11 5.1 9.4 1.0 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein Pkinase_Tyr PF07714.17 RLN74527.1 - 1.5e-14 53.9 0.0 2.7e-14 53.1 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RLN74527.1 - 4.8e-11 42.5 0.0 6.1e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 RLN74527.1 - 0.0056 17.5 0.0 0.023 15.6 0.0 1.9 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 RLN74527.1 - 0.038 14.1 0.1 0.077 13.1 0.1 1.6 1 0 0 1 1 1 0 Podoplanin SKG6 PF08693.10 RLN74527.1 - 0.11 11.9 1.4 0.34 10.4 1.4 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 RLN74527.1 - 0.11 12.2 1.4 0.22 11.3 1.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MIOX PF05153.15 RLN74528.1 - 2e-40 139.0 3.3 2.2e-40 138.8 3.3 1.0 1 0 0 1 1 1 1 Myo-inositol oxygenase Sdh5 PF03937.16 RLN74528.1 - 0.087 12.8 0.4 0.15 12.0 0.4 1.5 1 1 0 1 1 1 0 Flavinator of succinate dehydrogenase UCH PF00443.29 RLN74529.1 - 3.9e-36 124.9 0.0 4.1e-35 121.5 0.0 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN74529.1 - 6.3e-12 45.7 0.3 6.3e-12 45.7 0.3 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 RLN74529.1 - 1.9e-07 31.3 3.0 1.9e-07 31.3 3.0 2.2 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein ubiquitin PF00240.23 RLN74529.1 - 0.004 16.9 0.1 0.0097 15.6 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RLN74529.1 - 0.03 14.2 0.1 0.064 13.1 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like cNMP_binding PF00027.29 RLN74530.1 - 9.5e-36 121.8 0.7 7.8e-19 67.5 0.1 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 RLN74530.1 - 0.02 14.6 0.2 0.055 13.2 0.2 1.7 1 0 0 1 1 1 0 Cupin domain SDA1 PF05285.12 RLN74530.1 - 0.77 9.1 8.2 0.97 8.8 8.2 1.1 1 0 0 1 1 1 0 SDA1 SnoaL_2 PF12680.7 RLN74531.1 - 0.0044 17.6 0.3 0.014 16.0 0.1 2.1 2 0 0 2 2 2 1 SnoaL-like domain UPF0728 PF15092.6 RLN74531.1 - 0.12 12.3 0.0 0.91 9.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0728 EF-hand_1 PF00036.32 RLN74532.1 - 7.2e-12 44.0 0.3 6.2e-05 22.3 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN74532.1 - 3.6e-11 42.1 2.7 0.00029 20.5 0.4 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 RLN74532.1 - 4.9e-10 39.7 0.3 1.1e-07 32.2 0.2 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN74532.1 - 2.3e-09 36.3 2.3 0.00046 19.6 0.6 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RLN74532.1 - 2.6e-07 30.4 0.0 0.00016 21.5 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair TAF8_C PF10406.9 RLN74533.1 - 3.4e-11 43.5 1.0 6.5e-11 42.6 0.1 2.0 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 RLN74533.1 - 0.00053 20.0 0.1 0.0015 18.5 0.0 1.8 2 0 0 2 2 2 1 Bromodomain associated SKN1 PF03935.15 RLN74534.1 - 6.8e-63 212.8 13.0 4.7e-27 94.6 4.2 4.1 3 2 0 3 3 3 3 Beta-glucan synthesis-associated protein (SKN1) FAD_binding_2 PF00890.24 RLN74535.1 - 4.4e-121 404.9 2.9 6.5e-121 404.3 2.9 1.3 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 RLN74535.1 - 1e-42 145.2 1.6 1.5e-42 144.6 1.6 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 RLN74535.1 - 0.00012 21.4 0.7 0.019 14.2 0.2 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 RLN74535.1 - 0.0014 17.9 1.1 0.0029 16.9 1.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 RLN74535.1 - 0.011 14.8 5.2 0.037 13.1 3.8 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 RLN74535.1 - 0.02 13.6 0.7 0.058 12.1 1.0 1.7 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 RLN74535.1 - 0.021 14.4 0.9 0.031 13.9 0.2 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 RLN74535.1 - 0.039 13.2 1.8 0.041 13.1 0.4 1.7 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 RLN74535.1 - 1.1 8.5 4.3 2.3 7.5 4.3 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ank_4 PF13637.6 RLN74536.1 - 2.4e-16 59.9 5.0 3.8e-05 24.2 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN74536.1 - 1.4e-14 54.4 4.1 1e-08 35.6 0.2 2.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN74536.1 - 2e-13 50.3 6.0 0.0006 20.1 0.0 5.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN74536.1 - 3.7e-08 33.0 0.1 4.8 8.1 0.0 6.2 5 1 1 6 6 6 1 Ankyrin repeat HA PF03457.14 RLN74536.1 - 0.02 15.2 0.1 13 6.2 0.0 2.8 2 1 0 2 2 2 0 Helicase associated domain zf-C3HC4_3 PF13920.6 RLN74550.1 - 6.5e-19 67.5 18.9 3.1e-12 46.1 7.8 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN74550.1 - 1.6e-15 56.7 19.0 2.5e-10 40.0 7.0 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 RLN74550.1 - 6.9e-11 41.8 19.3 2.2e-05 24.2 6.8 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN74550.1 - 3.3e-10 39.8 19.4 1.5e-06 28.1 6.6 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RLN74550.1 - 1.4e-09 37.6 17.3 2e-05 24.3 7.6 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN74550.1 - 1.3e-08 34.8 17.7 0.0003 20.7 1.7 3.5 3 0 0 3 3 3 2 RING-type zinc-finger zf-RING_2 PF13639.6 RLN74550.1 - 1.4e-08 35.0 21.2 2.6e-06 27.7 8.1 2.4 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_4 PF15227.6 RLN74550.1 - 0.0001 22.4 18.6 0.062 13.5 2.9 3.1 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 RLN74550.1 - 0.31 11.0 10.4 0.76 9.7 2.4 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Seryl_tRNA_N PF02403.22 RLN74550.1 - 0.34 11.2 2.2 2 8.7 0.1 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-rbx1 PF12678.7 RLN74550.1 - 0.36 11.2 10.0 0.13 12.6 3.4 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain CcdA PF07362.12 RLN74550.1 - 0.5 10.8 9.2 0.76 10.2 2.4 2.7 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA DUF753 PF05444.12 RLN74550.1 - 0.91 9.5 11.6 2.1 8.3 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF753) zf-RING_4 PF14570.6 RLN74550.1 - 0.94 9.3 13.2 0.038 13.8 4.6 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TTKRSYEDQ PF10212.9 RLN74550.1 - 1.8 7.5 5.7 1.1 8.1 0.4 2.0 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein zf-RING_11 PF17123.5 RLN74550.1 - 2.3 8.0 18.7 1.7 8.4 4.2 3.5 3 0 0 3 3 3 0 RING-like zinc finger Ank_4 PF13637.6 RLN74551.1 - 5.6e-14 52.3 0.5 1.3e-08 35.2 0.0 3.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 RLN74551.1 - 1.2e-13 50.7 12.7 2.4e-13 49.7 12.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.6 RLN74551.1 - 5.2e-12 45.8 0.5 2.6e-08 34.0 0.6 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN74551.1 - 5.6e-10 39.7 0.2 0.0018 18.8 0.5 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PH PF00169.29 RLN74551.1 - 9.9e-10 38.9 0.1 3.4e-09 37.1 0.1 1.8 2 0 0 2 2 2 1 PH domain Ank PF00023.30 RLN74551.1 - 1.2e-09 38.2 0.7 0.0018 18.6 0.7 2.8 2 1 0 2 2 2 2 Ankyrin repeat Prok-RING_4 PF14447.6 RLN74551.1 - 3.3e-06 26.9 12.8 6.8e-06 25.9 12.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Ank_3 PF13606.6 RLN74551.1 - 6.3e-06 26.2 0.1 0.089 13.4 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat zf-RING_2 PF13639.6 RLN74551.1 - 1.1e-05 25.6 14.1 1.1e-05 25.6 14.1 2.0 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 RLN74551.1 - 6.4e-05 22.7 14.8 0.00014 21.7 14.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN74551.1 - 0.0012 18.6 14.2 0.0022 17.8 14.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN74551.1 - 0.29 11.1 16.8 0.042 13.8 12.6 1.9 2 0 0 2 2 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 RLN74551.1 - 4 7.5 10.2 1.7 8.7 6.3 2.2 1 1 1 2 2 2 0 RING-type zinc-finger Pkinase_Tyr PF07714.17 RLN74552.1 - 1.7e-32 112.8 0.0 2.4e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN74552.1 - 3.8e-31 108.4 0.0 6.3e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 RLN74552.1 - 1.4e-12 48.0 4.5 6.1e-08 33.1 0.6 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) zf-C3HC4_3 PF13920.6 RLN74552.1 - 5.1e-11 42.3 10.1 9.2e-11 41.4 10.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.6 RLN74552.1 - 1.4e-10 41.2 1.7 5.6e-10 39.3 0.9 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN74552.1 - 2.5e-10 40.7 0.6 0.005 17.4 0.0 3.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN74552.1 - 1.1e-08 35.1 0.9 0.00051 20.4 0.2 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 RLN74552.1 - 7.9e-05 22.8 0.3 0.18 12.5 0.0 3.4 4 0 0 4 4 2 1 Ankyrin repeat Prok-RING_4 PF14447.6 RLN74552.1 - 0.00025 20.9 11.1 0.00049 19.9 11.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 RLN74552.1 - 0.00042 20.6 11.4 0.0011 19.3 11.4 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RLN74552.1 - 0.0014 18.4 11.8 0.0028 17.5 11.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) EphA2_TM PF14575.6 RLN74552.1 - 0.0064 17.3 0.0 0.016 16.1 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 RLN74552.1 - 0.0067 15.8 3.4 0.014 14.8 3.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 RLN74552.1 - 0.0096 16.0 0.5 0.026 14.6 0.5 1.7 1 0 0 1 1 1 1 Podoplanin zf-C3HC4_2 PF13923.6 RLN74552.1 - 0.0096 15.8 13.1 0.021 14.7 13.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TMEM154 PF15102.6 RLN74552.1 - 0.012 15.5 0.1 0.026 14.4 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family CD34_antigen PF06365.12 RLN74552.1 - 0.021 14.4 0.1 0.042 13.4 0.1 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF4690 PF15756.5 RLN74552.1 - 0.027 15.1 0.8 0.027 15.1 0.8 2.0 2 0 0 2 2 1 0 Small Novel Rich in Cartilage Plasmodium_Vir PF05795.11 RLN74552.1 - 0.029 13.8 0.7 0.044 13.2 0.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein zf-RING_5 PF14634.6 RLN74552.1 - 0.043 13.8 11.2 0.099 12.6 11.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain MLANA PF14991.6 RLN74552.1 - 0.047 14.0 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A SpoIIIAH PF12685.7 RLN74552.1 - 0.048 13.5 3.8 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein zf-RING_UBOX PF13445.6 RLN74552.1 - 0.13 12.3 5.0 0.23 11.5 4.5 1.8 1 1 0 1 1 1 0 RING-type zinc-finger DUF1180 PF06679.12 RLN74552.1 - 0.42 11.0 2.1 0.69 10.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) FAM176 PF14851.6 RLN74552.1 - 0.63 9.7 0.0 0.63 9.7 0.0 2.2 1 1 1 2 2 2 0 FAM176 family zf-C3HC4_4 PF15227.6 RLN74552.1 - 1 9.6 10.1 2.2 8.5 10.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Sas6_CC PF18594.1 RLN74552.1 - 3.8 7.4 5.0 0.65 9.8 0.6 2.0 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain Ank_2 PF12796.7 RLN74553.1 - 4.4e-11 43.2 0.1 2.6e-05 24.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN74553.1 - 5.7e-09 36.1 0.9 6.8e-06 26.3 0.4 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN74553.1 - 3.1e-07 30.6 0.1 0.033 14.6 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 RLN74553.1 - 2.7e-06 27.3 0.0 0.088 13.4 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat PH PF00169.29 RLN74553.1 - 5.9e-05 23.5 0.3 0.00017 22.0 0.3 1.8 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 RLN74553.1 - 7.3e-05 23.2 0.3 0.027 15.1 0.1 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) RVT_1 PF00078.27 RLN74560.1 - 1.5e-13 50.8 0.0 3.8e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFIIS_M PF07500.14 RLN74560.1 - 0.072 13.6 1.2 0.3 11.6 0.4 2.2 1 1 2 3 3 3 0 Transcription factor S-II (TFIIS), central domain DUF2959 PF11172.8 RLN74560.1 - 0.2 11.8 3.6 0.29 11.3 2.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) TetR_C_6 PF13977.6 RLN74560.1 - 5.7 7.2 10.4 0.55 10.5 4.6 2.4 2 1 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal Stealth_CR2 PF11380.8 RLN74561.1 - 3.1e-46 156.0 0.0 1.1e-45 154.3 0.0 1.9 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR4 PF17103.5 RLN74561.1 - 1.6e-16 59.9 0.0 4.7e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Notch PF00066.17 RLN74561.1 - 5.6e-15 55.5 27.8 1.2e-07 32.0 9.1 2.5 2 0 0 2 2 2 2 LNR domain Stealth_CR3 PF17102.5 RLN74561.1 - 1.3e-14 53.8 4.1 1.3e-14 53.8 4.1 2.5 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 RLN74561.1 - 3.8e-11 42.5 2.0 2.4e-10 39.9 2.3 2.2 2 0 0 2 2 2 1 Stealth protein CR1, conserved region 1 DUF2892 PF11127.8 RLN74561.1 - 0.054 13.5 3.3 0.61 10.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) ATG16 PF08614.11 RLN74562.1 - 0.0016 18.7 11.2 0.002 18.4 11.2 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF3552 PF12072.8 RLN74562.1 - 0.0074 15.7 12.5 0.0098 15.3 12.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Spc7 PF08317.11 RLN74562.1 - 0.02 13.8 9.4 0.026 13.4 9.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ZapB PF06005.12 RLN74562.1 - 0.045 14.2 6.9 0.045 14.2 6.9 2.3 1 1 1 2 2 2 0 Cell division protein ZapB BRE1 PF08647.11 RLN74562.1 - 0.17 11.9 13.5 0.15 12.1 11.9 1.7 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase KxDL PF10241.9 RLN74562.1 - 0.33 11.3 14.0 2 8.7 4.3 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein ADIP PF11559.8 RLN74562.1 - 1.3 9.1 16.0 3.4 7.8 15.9 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF5595 PF18077.1 RLN74562.1 - 1.4 9.1 5.2 1.2 9.3 1.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) Exonuc_VII_L PF02601.15 RLN74562.1 - 1.4 8.4 10.9 1.8 8.1 10.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.11 RLN74562.1 - 1.9 8.6 17.5 21 5.2 17.5 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus OmpH PF03938.14 RLN74562.1 - 3 8.2 15.5 4.2 7.7 15.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 RLN74562.1 - 3.5 6.9 14.0 0.77 9.1 4.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) YabA PF06156.13 RLN74562.1 - 5.5 7.7 10.3 59 4.4 10.0 2.3 1 1 0 1 1 1 0 Initiation control protein YabA Cut12 PF11500.8 RLN74562.1 - 9.1 6.2 11.5 7.9 6.4 9.2 2.1 1 1 1 2 2 2 0 Spindle pole body formation-associated protein Tox-REase-9 PF15650.6 RLN74563.1 - 0.0089 16.3 0.0 4.8 7.6 0.0 2.5 2 0 0 2 2 2 2 Restriction endonuclease fold toxin 9 HECT PF00632.25 RLN74570.1 - 9.3e-77 258.5 0.0 2.5e-76 257.1 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF3464 PF11947.8 RLN74570.1 - 0.074 12.8 1.3 0.14 11.9 1.3 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 RXT2_N PF08595.11 RLN74570.1 - 6.5 6.8 7.4 10 6.1 3.7 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal PTPRCAP PF15713.5 RLN74570.1 - 10 6.4 12.6 6.1 7.1 6.7 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated RRM_1 PF00076.22 RLN74571.1 - 7e-17 61.0 0.0 2.3e-16 59.4 0.0 1.9 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 RLN74571.1 - 9.9e-05 22.2 1.1 0.00019 21.3 1.1 1.5 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.6 RLN74571.1 - 0.0003 20.4 0.0 0.00054 19.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.6 RLN74571.1 - 0.0012 18.8 0.2 0.0023 17.8 0.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 RLN74571.1 - 0.03 14.2 0.2 0.069 13.0 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 RLN74571.1 - 0.13 12.0 0.6 0.23 11.2 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle MAGE_N PF12440.8 RLN74571.1 - 8.2 7.2 10.9 0.92 10.2 0.5 2.6 3 0 0 3 3 3 0 Melanoma associated antigen family N terminal MTCP1 PF08991.10 RLN74572.1 - 0.0085 16.3 6.2 0.011 15.9 6.2 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 RLN74572.1 - 0.011 15.8 7.4 0.019 15.1 7.4 1.3 1 0 0 1 1 1 0 CHCH domain CX9C PF16860.5 RLN74572.1 - 0.051 13.6 5.6 0.069 13.2 5.6 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 RLN74572.1 - 0.11 12.3 5.7 0.14 11.9 5.7 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) EF-hand_7 PF13499.6 RLN74573.1 - 2.1e-16 60.1 2.5 8.2e-16 58.2 1.2 2.7 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN74573.1 - 0.00029 20.5 0.3 0.014 15.3 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_13 PF17958.1 RLN74573.1 - 0.0046 16.7 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.9 RLN74573.1 - 0.03 14.6 0.3 4.9 7.5 0.0 2.6 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_1 PF00036.32 RLN74573.1 - 0.06 12.9 5.8 0.51 10.0 0.0 3.7 4 0 0 4 4 4 0 EF hand DUF4187 PF13821.6 RLN74573.1 - 0.084 12.7 0.3 0.24 11.2 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) EF-hand_5 PF13202.6 RLN74573.1 - 0.092 12.3 0.2 0.33 10.5 0.0 2.2 2 0 0 2 2 2 0 EF hand SDA1 PF05285.12 RLN74573.1 - 1.7 8.0 10.9 0.011 15.2 2.2 1.6 2 0 0 2 2 2 0 SDA1 MPP6 PF10175.9 RLN74574.1 - 8.8e-15 55.4 1.4 1.1e-14 55.1 1.4 1.2 1 0 0 1 1 1 1 M-phase phosphoprotein 6 Androgen_recep PF02166.16 RLN74574.1 - 0.045 12.6 0.2 0.057 12.3 0.2 1.1 1 0 0 1 1 1 0 Androgen receptor Ribosomal_L18_c PF14204.6 RLN74574.1 - 0.89 10.5 6.7 6.2 7.8 4.3 2.2 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region LRR_6 PF13516.6 RLN74581.1 - 3.7e-13 48.4 16.3 0.0026 17.7 0.0 9.3 11 1 1 12 12 12 3 Leucine Rich repeat Mpv17_PMP22 PF04117.12 RLN74581.1 - 8.2e-13 48.4 0.7 1.7e-12 47.4 0.7 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family LRR_4 PF12799.7 RLN74581.1 - 1.1e-11 44.8 2.8 0.039 14.4 0.0 5.6 2 2 5 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN74581.1 - 4.3e-06 26.4 0.2 0.046 13.5 0.0 4.2 3 1 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 RLN74581.1 - 4e-05 23.6 9.3 6.5 7.7 0.1 7.4 9 1 0 9 9 9 2 Leucine Rich Repeat LMBR1 PF04791.16 RLN74582.1 - 1.5e-07 30.7 11.9 1.5e-07 30.7 11.9 2.7 1 1 1 2 2 2 1 LMBR1-like membrane protein COPIIcoated_ERV PF07970.12 RLN74583.1 - 2.2e-42 145.4 0.2 3.1e-42 144.9 0.2 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 RLN74583.1 - 3.1e-16 59.5 0.0 9.7e-16 57.9 0.0 2.0 1 1 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SsgA PF04686.12 RLN74583.1 - 0.097 12.7 0.1 0.9 9.6 0.0 2.5 3 0 0 3 3 3 0 Streptomyces sporulation and cell division protein, SsgA DUF2109 PF09882.9 RLN74584.1 - 0.36 10.9 2.3 5.3 7.1 0.2 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) DUF2183 PF09949.9 RLN74585.1 - 0.13 12.6 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) Methyltransf_28 PF02636.17 RLN74586.1 - 5.3e-72 242.6 0.0 1.6e-71 241.0 0.0 1.7 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 RLN74586.1 - 0.069 13.9 0.0 0.64 10.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Ribosomal_L16 PF00252.18 RLN74587.1 - 1.1e-37 129.0 0.0 1.3e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Leu_Phe_trans PF03588.14 RLN74591.1 - 3.3e-22 78.8 0.0 5.1e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase RasGEF PF00617.19 RLN74592.1 - 8.7e-40 136.8 0.2 1.3e-39 136.2 0.2 1.3 1 0 0 1 1 1 1 RasGEF domain DUF3275 PF11679.8 RLN74603.1 - 0.1 12.6 0.3 0.24 11.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Aldo_ket_red PF00248.21 RLN74607.1 - 2.1e-68 230.7 0.0 2.5e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AAA PF00004.29 RLN74608.1 - 7.3e-35 120.3 0.0 1.6e-34 119.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 RLN74608.1 - 4.8e-08 32.9 0.0 7.7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RLN74608.1 - 2.4e-05 24.5 2.1 0.00016 21.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RLN74608.1 - 3.6e-05 24.1 1.5 0.077 13.3 0.0 2.8 2 2 1 3 3 3 2 AAA domain Nucleolin_bd PF16725.5 RLN74608.1 - 9.9e-05 21.9 0.1 0.00025 20.6 0.1 1.7 1 0 0 1 1 1 1 Nucleolin binding domain AAA_5 PF07728.14 RLN74608.1 - 0.00012 22.1 0.2 0.0012 18.8 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 RLN74608.1 - 0.00029 20.2 0.0 0.0005 19.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 RLN74608.1 - 0.00038 20.1 2.7 0.19 11.3 0.1 3.1 2 1 1 3 3 3 2 AAA domain AAA_2 PF07724.14 RLN74608.1 - 0.00064 19.9 0.1 0.0034 17.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 RLN74608.1 - 0.00092 19.6 0.5 0.00092 19.6 0.5 3.3 2 2 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 RLN74608.1 - 0.0021 17.5 0.2 0.0074 15.7 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 RLN74608.1 - 0.0029 17.4 0.1 0.0069 16.1 0.1 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 RLN74608.1 - 0.0033 17.4 1.1 0.044 13.7 0.0 2.8 2 2 1 3 3 3 1 NACHT domain RNA_helicase PF00910.22 RLN74608.1 - 0.0053 17.1 0.0 0.01 16.2 0.0 1.6 1 1 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 RLN74608.1 - 0.0092 16.5 0.6 0.12 12.9 0.0 2.6 2 1 1 3 3 3 1 ABC transporter AAA_14 PF13173.6 RLN74608.1 - 0.029 14.4 0.0 0.084 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RLN74608.1 - 0.032 14.5 1.0 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RLN74608.1 - 0.037 14.6 0.0 0.19 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 RLN74608.1 - 0.04 13.1 0.0 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 RLN74608.1 - 0.053 13.2 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain CPT PF07931.12 RLN74608.1 - 0.055 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_11 PF13086.6 RLN74608.1 - 0.056 13.2 2.9 0.41 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain DDE_Tnp_IS66 PF03050.14 RLN74608.1 - 0.061 12.8 2.5 0.1 12.1 2.5 1.3 1 0 0 1 1 1 0 Transposase IS66 family Parvo_NS1 PF01057.17 RLN74608.1 - 0.076 12.1 0.1 0.46 9.5 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Hydin_ADK PF17213.3 RLN74608.1 - 0.076 13.3 3.5 0.63 10.3 0.0 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_3 PF07726.11 RLN74608.1 - 0.081 12.8 0.0 0.17 11.8 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 RLN74608.1 - 0.14 11.7 0.0 0.45 10.0 0.0 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region SKN1 PF03935.15 RLN74618.1 - 1.3e-61 208.5 15.3 1.6e-25 89.5 5.3 4.0 3 2 0 3 3 3 3 Beta-glucan synthesis-associated protein (SKN1) SnoaL_2 PF12680.7 RLN74619.1 - 0.00096 19.8 0.2 0.0026 18.4 0.0 1.9 2 0 0 2 2 2 1 SnoaL-like domain Cnn_1N PF07989.11 RLN74619.1 - 0.97 9.6 4.6 0.56 10.4 0.9 2.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 RLN74619.1 - 1.6 8.6 4.7 0.61 9.9 0.5 2.3 2 0 0 2 2 2 0 Septum formation initiator EF-hand_1 PF00036.32 RLN74620.1 - 5e-12 44.5 0.5 7.3e-05 22.0 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 RLN74620.1 - 1e-11 45.1 6.0 1e-07 32.3 0.2 2.6 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RLN74620.1 - 4.1e-11 41.9 4.2 0.00024 20.8 0.0 3.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 RLN74620.1 - 6.3e-09 34.9 2.5 0.00047 19.5 0.6 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RLN74620.1 - 4e-07 29.8 0.0 0.00025 20.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair NPIP PF06409.11 RLN74621.1 - 0.68 8.9 2.1 3.4 6.6 0.1 2.2 2 0 0 2 2 2 0 Nuclear pore complex interacting protein (NPIP) UCH PF00443.29 RLN74622.1 - 1.6e-36 126.1 0.0 3.5e-36 125.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN74622.1 - 1.4e-12 47.8 1.9 1.6e-12 47.6 0.3 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 RLN74622.1 - 4.8e-08 33.2 6.7 6.2e-08 32.9 3.7 2.6 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein ubiquitin PF00240.23 RLN74622.1 - 0.0022 17.7 0.1 0.0044 16.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RLN74622.1 - 0.014 15.2 0.1 0.029 14.2 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 RLN74622.1 - 0.13 12.3 0.2 0.32 11.1 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain cNMP_binding PF00027.29 RLN74623.1 - 9.6e-37 124.9 0.7 1.2e-19 70.2 0.1 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 RLN74623.1 - 0.016 14.9 0.7 0.035 13.8 0.1 1.9 2 0 0 2 2 2 0 Cupin domain SDA1 PF05285.12 RLN74623.1 - 1.5 8.2 7.4 1.8 7.9 7.4 1.1 1 0 0 1 1 1 0 SDA1 FAD_binding_2 PF00890.24 RLN74624.1 - 5.2e-63 213.6 0.4 8.7e-63 212.8 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 RLN74624.1 - 5e-43 146.2 1.6 6.9e-43 145.7 1.6 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term TAF8_C PF10406.9 RLN74625.1 - 5.3e-11 42.9 0.3 1.8e-10 41.2 0.0 2.1 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 RLN74625.1 - 7.9e-05 22.6 0.1 0.00097 19.1 0.1 2.3 1 1 0 1 1 1 1 Bromodomain associated MIOX PF05153.15 RLN74626.1 - 1.6e-39 136.0 3.9 1.7e-39 135.9 3.9 1.0 1 0 0 1 1 1 1 Myo-inositol oxygenase Sdh5 PF03937.16 RLN74626.1 - 0.041 13.9 0.1 0.062 13.3 0.1 1.4 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase SepSecS PF05889.13 RLN74641.1 - 6.9e-109 364.1 0.0 2.8e-108 362.1 0.0 1.8 1 1 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 RLN74641.1 - 5.1e-05 22.7 0.1 6.9e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 RLN74641.1 - 0.0059 15.4 0.0 0.0084 14.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Glyco_transf_20 PF00982.21 RLN74641.1 - 0.25 9.9 0.0 0.4 9.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 20 TPR_12 PF13424.6 RLN74642.1 - 2.8e-11 43.6 4.4 8.3e-06 26.0 0.0 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN74642.1 - 0.00014 21.6 4.1 0.0088 15.9 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN74642.1 - 0.053 13.4 2.9 15 5.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Snf7 PF03357.21 RLN74643.1 - 3.2e-18 65.9 10.9 2.4e-10 40.3 3.7 2.1 2 0 0 2 2 2 2 Snf7 Arf PF00025.21 RLN74644.1 - 1.4e-28 99.5 0.8 1.8e-16 60.1 0.0 3.0 2 1 1 3 3 3 3 ADP-ribosylation factor family UBA PF00627.31 RLN74649.1 - 3e-07 30.2 0.8 0.0004 20.2 0.2 2.8 2 0 0 2 2 2 2 UBA/TS-N domain UIM PF02809.20 RLN74649.1 - 0.0069 16.2 4.1 0.039 13.9 4.1 2.5 1 0 0 1 1 1 1 Ubiquitin interaction motif Ribosomal_L50 PF10501.9 RLN74649.1 - 0.034 14.3 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 Ribosomal subunit 39S ZapB PF06005.12 RLN74660.1 - 0.026 14.9 1.3 0.026 14.9 1.3 3.9 3 1 1 4 4 4 0 Cell division protein ZapB ImpA_N PF06812.12 RLN74660.1 - 0.057 13.5 4.5 1.4 9.0 1.6 3.5 3 1 0 3 3 3 0 ImpA, N-terminal, type VI secretion system SOGA PF11365.8 RLN74660.1 - 1.2 10.4 11.4 0.34 12.1 2.1 3.3 3 0 0 3 3 3 0 Protein SOGA CENP-F_leu_zip PF10473.9 RLN74660.1 - 1.3 9.0 17.8 1.8 8.6 12.5 2.7 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Com_YlbF PF06133.11 RLN74660.1 - 1.7 9.3 6.5 6.8 7.3 1.3 2.7 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA HALZ PF02183.18 RLN74660.1 - 2.2 8.6 6.5 58 4.0 0.2 3.8 2 1 1 3 3 3 0 Homeobox associated leucine zipper BRE1 PF08647.11 RLN74660.1 - 4.3 7.5 13.1 3.3 7.8 0.1 3.4 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase YabA PF06156.13 RLN74660.1 - 6.6 7.4 6.1 21 5.8 0.2 3.3 3 0 0 3 3 3 0 Initiation control protein YabA Sacchrp_dh_NADP PF03435.18 RLN74661.1 - 6.8e-16 58.7 0.9 1.2e-15 57.9 0.9 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 RLN74661.1 - 0.0039 16.8 2.0 0.024 14.2 2.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 RLN74661.1 - 0.052 13.4 1.9 0.43 10.4 1.9 2.2 1 1 0 1 1 1 0 NAD(P)H-binding Ribosomal_L21p PF00829.21 RLN74664.1 - 3.6e-33 113.8 3.8 4.4e-33 113.6 3.8 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Baculo_PEP_C PF04513.12 RLN74686.1 - 0.0048 16.9 0.8 0.018 15.1 0.8 1.9 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2457 PF10446.9 RLN74688.1 - 1.7 7.7 11.9 2.7 7.0 11.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_photolyase PF00875.18 RLN74689.1 - 6.5e-07 29.5 2.2 1.3e-06 28.5 0.8 2.2 2 1 0 2 2 2 1 DNA photolyase FAD_binding_7 PF03441.14 RLN74689.1 - 0.00021 20.8 1.1 0.00043 19.8 0.6 1.8 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase RINGv PF12906.7 RLN74690.1 - 1.3e-14 54.0 5.5 1.3e-14 54.0 5.5 1.9 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.6 RLN74690.1 - 0.0024 18.1 5.8 0.0056 17.0 5.8 1.7 1 0 0 1 1 1 1 Ring finger domain SWIB PF02201.18 RLN74691.1 - 9.8e-58 192.0 0.4 1.7e-27 95.1 0.0 2.5 3 0 0 3 3 2 2 SWIB/MDM2 domain DEK_C PF08766.11 RLN74691.1 - 7.3e-16 57.8 0.4 4e-15 55.5 0.6 2.1 2 0 0 2 2 2 1 DEK C terminal domain YL1 PF05764.13 RLN74691.1 - 0.006 16.7 13.4 0.006 16.7 13.4 2.4 2 1 0 2 2 2 1 YL1 nuclear protein TIMELESS_C PF05029.13 RLN74691.1 - 0.0083 15.3 10.7 0.0083 15.3 10.7 2.2 2 0 0 2 2 2 2 Timeless protein C terminal region DUF2052 PF09747.9 RLN74691.1 - 0.015 15.5 18.3 0.027 14.6 14.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DAP10 PF07213.11 RLN74691.1 - 0.096 12.7 0.0 2.8 8.0 0.0 2.2 2 0 0 2 2 2 0 DAP10 membrane protein RR_TM4-6 PF06459.12 RLN74691.1 - 0.21 11.4 17.6 0.12 12.2 12.0 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 RLN74691.1 - 0.47 8.3 3.3 2.8 5.8 1.6 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family GAGA_bind PF06217.12 RLN74691.1 - 1.5 9.0 10.0 1.3 9.3 5.1 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family DUF2868 PF11067.8 RLN74691.1 - 3.2 7.2 8.6 0.6 9.6 4.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) NPR3 PF03666.13 RLN74691.1 - 3.2 6.4 8.5 0.62 8.8 3.1 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 RLN74691.1 - 7.2 5.3 10.4 3.7 6.2 7.4 1.8 2 0 0 2 2 2 0 Presenilin PTPRCAP PF15713.5 RLN74691.1 - 7.3 6.9 22.1 7.3 6.9 15.7 2.6 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated Hid1 PF12722.7 RLN74691.1 - 8.2 4.4 8.3 0.62 8.1 3.6 1.5 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein DUF913 PF06025.12 RLN74691.1 - 8.6 5.2 7.3 8.6 5.2 4.5 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) PDZ PF00595.24 RLN74693.1 - 8.8e-20 70.9 0.1 8.7e-05 22.8 0.0 5.6 5 0 0 5 5 5 4 PDZ domain PDZ_6 PF17820.1 RLN74693.1 - 2.5e-15 56.0 0.1 0.043 13.7 0.0 5.4 5 0 0 5 5 5 5 PDZ domain PDZ_2 PF13180.6 RLN74693.1 - 4.7e-05 23.6 2.2 0.63 10.4 0.2 4.3 4 0 0 4 4 4 1 PDZ domain zf-MYND PF01753.18 RLN74693.1 - 0.0095 16.0 3.2 0.019 15.0 3.2 1.5 1 0 0 1 1 1 1 MYND finger Tox-URI2 PF15653.6 RLN74693.1 - 0.016 15.5 0.1 0.043 14.1 0.1 1.7 1 0 0 1 1 1 0 URI fold toxin 2 YL1 PF05764.13 RLN74693.1 - 1.5 8.9 21.4 0.013 15.7 11.8 2.1 2 0 0 2 2 2 0 YL1 nuclear protein CENP-F_leu_zip PF10473.9 RLN74694.1 - 0.00084 19.4 17.0 0.11 12.6 1.8 3.1 2 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Titin_Ig-rpts PF06582.12 RLN74694.1 - 0.43 10.6 3.9 47 4.0 0.1 3.5 3 0 0 3 3 3 0 Titin repeat Nsp1_C PF05064.13 RLN74694.1 - 3.8 7.4 9.9 11 5.9 2.2 3.1 2 1 1 3 3 3 0 Nsp1-like C-terminal region Syntaxin-6_N PF09177.11 RLN74694.1 - 4.1 8.0 7.8 0.67 10.5 2.9 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Mpp10 PF04006.12 RLN74695.1 - 5e-146 487.7 58.0 6.4e-146 487.3 58.0 1.0 1 0 0 1 1 1 1 Mpp10 protein MetOD1 PF18546.1 RLN74695.1 - 0.1 12.6 0.5 0.25 11.3 0.5 1.6 1 0 0 1 1 1 0 Metanogen output domain 1 DDE_1 PF03184.19 RLN74696.1 - 5e-05 23.0 0.0 5.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease adh_short PF00106.25 RLN74697.1 - 4.6e-42 143.7 3.9 9e-42 142.7 3.9 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN74697.1 - 6.1e-33 114.3 0.3 1.7e-32 112.9 0.3 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN74697.1 - 6.3e-13 49.0 2.1 3.5e-12 46.6 2.1 1.9 1 1 0 1 1 1 1 KR domain Rho_RNA_bind PF07497.12 RLN74697.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain DUF4158 PF13700.6 RLN74697.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) UQ_con PF00179.26 RLN74698.1 - 5.3e-23 81.2 0.0 8.8e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme HTH_21 PF13276.6 RLN74699.1 - 1.8e-05 24.7 0.0 3.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 HTH-like domain DnaJ PF00226.31 RLN74700.1 - 2.7e-24 85.0 0.4 5.2e-24 84.1 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 RLN74700.1 - 5.8e-19 68.3 0.7 1.2e-18 67.3 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) TPR_2 PF07719.17 RLN74700.1 - 0.011 15.7 0.0 0.033 14.3 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat JIP_LZII PF16471.5 RLN74701.1 - 0.11 12.7 0.7 0.31 11.2 0.7 1.8 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Pyridoxal_deC PF00282.19 RLN74702.1 - 5.3e-80 268.9 0.0 8.1e-80 268.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain PX PF00787.24 RLN74718.1 - 3.7e-09 36.6 0.0 5e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 PX domain Aldo_ket_red PF00248.21 RLN74719.1 - 1.8e-63 214.5 0.0 2e-63 214.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4536 PF15055.6 RLN74720.1 - 0.13 12.5 0.4 0.45 10.8 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4536) TMEM51 PF15345.6 RLN74728.1 - 0.037 13.9 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF2371 PF10177.9 RLN74728.1 - 0.11 12.6 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) LSR PF05624.14 RLN74728.1 - 4.7 7.3 6.3 7.5 6.6 6.3 1.2 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) TMEM154 PF15102.6 RLN74728.1 - 8.1 6.4 10.3 11 5.9 2.6 2.1 1 1 1 2 2 2 0 TMEM154 protein family DUF4337 PF14235.6 RLN74729.1 - 0.076 13.1 1.9 0.17 12.0 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Aldo_ket_red PF00248.21 RLN74736.1 - 5e-55 186.8 0.0 4e-30 105.0 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family HSF_DNA-bind PF00447.17 RLN74736.1 - 8.7e-21 74.4 0.3 1.7e-20 73.4 0.3 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding HSF_DNA-bind PF00447.17 RLN74737.1 - 1.5e-20 73.6 0.7 3.3e-20 72.5 0.7 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding DUF5532 PF17673.1 RLN74737.1 - 0.075 13.1 1.1 0.17 12.0 1.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5532) LPMO_10 PF03067.15 RLN74738.1 - 1.9e-05 25.4 0.0 0.00058 20.6 0.0 2.3 1 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Sporozoite_P67 PF05642.11 RLN74738.1 - 0.14 10.2 4.4 0.14 10.3 4.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.11 RLN74738.1 - 1.1 7.3 17.7 2 6.5 17.7 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MGC-24 PF05283.11 RLN74738.1 - 4 7.9 12.2 1.6 9.1 8.1 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin LRR_4 PF12799.7 RLN74739.1 - 9.1e-12 45.0 0.7 2.6e-06 27.6 0.0 3.4 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN74739.1 - 1.4e-07 31.2 0.1 0.0044 16.5 0.0 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 RLN74739.1 - 0.0088 15.8 3.5 0.062 13.1 0.2 3.4 1 1 2 3 3 3 1 Leucine rich repeat ArgJ PF01960.18 RLN74740.1 - 2e-50 171.6 0.0 2.4e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 ArgJ family Ank_2 PF12796.7 RLN74742.1 - 0.00044 20.8 0.0 0.0011 19.5 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Iwr1 PF08574.10 RLN74742.1 - 0.0035 18.3 3.7 0.011 16.7 3.7 1.9 1 0 0 1 1 1 1 Transcription factor Iwr1 WW PF00397.26 RLN74748.1 - 1.9e-08 34.2 0.4 3.4e-08 33.4 0.4 1.4 1 0 0 1 1 1 1 WW domain Urb2 PF10441.9 RLN74749.1 - 9.3e-24 84.5 13.3 8.7e-23 81.3 3.3 3.7 3 0 0 3 3 3 2 Urb2/Npa2 family TetR_C_1 PF02909.17 RLN74749.1 - 0.0031 17.3 1.4 0.027 14.3 0.2 3.0 3 0 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain DUF3361 PF11841.8 RLN74749.1 - 0.12 12.3 0.5 2.1 8.3 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) C2 PF00168.30 RLN74756.1 - 2.5e-11 43.8 0.0 8.6e-11 42.1 0.0 1.8 1 1 0 1 1 1 1 C2 domain G_path_suppress PF15991.5 RLN74756.1 - 0.29 11.3 21.2 0.36 10.9 21.2 1.1 1 0 0 1 1 1 0 G-protein pathway suppressor Ax_dynein_light PF10211.9 RLN74757.1 - 0.097 12.6 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain Hepsin-SRCR PF09272.10 RLN74759.1 - 0.12 12.9 0.4 0.34 11.4 0.1 1.9 3 0 0 3 3 3 0 Hepsin, SRCR domain KIX_2 PF16987.5 RLN74765.1 - 0.026 14.5 0.1 0.053 13.5 0.1 1.6 1 1 0 1 1 1 0 KIX domain KIX_2 PF16987.5 RLN74766.1 - 0.0065 16.4 0.3 0.013 15.5 0.3 1.5 1 1 0 1 1 1 1 KIX domain DEAD PF00270.29 RLN74767.1 - 3.9e-28 98.4 0.0 8.7e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN74767.1 - 7.9e-23 80.9 0.1 1.6e-22 80.0 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 RLN74767.1 - 0.014 15.1 0.1 0.033 13.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 RLN74767.1 - 0.024 14.6 0.0 0.094 12.7 0.0 1.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 RLN74767.1 - 0.08 13.1 0.0 0.21 11.7 0.0 1.6 2 0 0 2 2 2 0 Helicase C-terminal domain PA PF02225.22 RLN74771.1 - 3.2e-11 43.1 1.2 1.8e-10 40.7 0.0 2.2 2 0 0 2 2 2 1 PA domain Big_3_5 PF16640.5 RLN74771.1 - 0.16 12.1 3.0 0.18 12.0 0.5 2.1 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) TFR_dimer PF04253.15 RLN74772.1 - 5.3e-28 97.6 0.0 9.9e-28 96.7 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 RLN74772.1 - 6.2e-19 68.5 0.0 1.7e-18 67.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 RLN74772.1 - 1.5e-09 37.7 0.0 6.4e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 RLN74772.1 - 0.055 13.2 0.0 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M20/M25/M40 NUFIP1 PF10453.9 RLN74775.1 - 0.0046 16.8 0.0 0.0091 15.8 0.0 1.4 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) GN3L_Grn1 PF08701.11 RLN74782.1 - 2.2e-17 62.9 19.9 2.2e-17 62.9 19.9 2.6 2 1 1 3 3 3 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 RLN74782.1 - 7.2e-14 51.8 0.2 6.7e-11 42.3 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN74782.1 - 5.7e-09 35.7 0.2 0.00041 19.9 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RLN74782.1 - 7.4e-06 26.0 0.3 0.049 13.5 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 RLN74782.1 - 0.00041 20.8 6.2 0.00049 20.5 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain cobW PF02492.19 RLN74782.1 - 0.00089 18.9 0.4 0.071 12.7 0.0 2.7 2 1 1 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain Nuc_deoxyri_tr2 PF15891.5 RLN74782.1 - 0.0016 18.7 0.7 0.0052 17.1 0.7 2.0 1 1 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like MeaB PF03308.16 RLN74782.1 - 0.0016 17.4 0.0 0.0016 17.4 0.0 2.6 2 1 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 RLN74782.1 - 0.0023 17.5 4.7 0.011 15.2 0.1 3.2 3 1 1 4 4 4 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 RLN74782.1 - 0.0047 17.0 3.6 0.023 14.8 0.1 3.1 2 2 1 3 3 3 1 Dynamin family SRPRB PF09439.10 RLN74782.1 - 0.019 14.4 0.0 0.059 12.8 0.0 1.8 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 RLN74782.1 - 0.032 14.8 0.0 0.032 14.8 0.0 2.8 3 1 0 3 3 2 0 AAA domain Roc PF08477.13 RLN74782.1 - 0.05 13.8 0.0 1.7 8.9 0.0 2.8 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 RLN74782.1 - 0.07 13.7 0.2 0.92 10.0 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Arf PF00025.21 RLN74782.1 - 0.074 12.5 0.1 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AIG1 PF04548.16 RLN74782.1 - 0.11 11.8 0.4 1.2 8.5 0.0 2.6 2 1 1 3 3 3 0 AIG1 family AAA_24 PF13479.6 RLN74782.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 RLN74782.1 - 0.55 9.5 4.6 1.2 8.4 4.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 RLN74783.1 - 2e-23 82.8 12.7 2e-23 82.8 12.7 7.1 3 2 4 8 8 8 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 RLN74783.1 - 6.5e-06 26.0 13.6 6.5e-06 26.0 13.6 8.3 7 2 1 8 8 8 2 TATA element modulatory factor 1 DNA binding Ras PF00071.22 RLN74794.1 - 0.092 12.3 0.1 0.97 9.0 0.0 2.2 2 0 0 2 2 2 0 Ras family CbiA PF01656.23 RLN74794.1 - 0.1 12.7 0.0 0.27 11.3 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 RLN74794.1 - 0.1 12.1 0.1 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Chordopox_A20R PF05941.13 RLN74794.1 - 0.12 11.3 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus A20R protein AAA_10 PF12846.7 RLN74794.1 - 0.22 10.4 0.0 0.37 9.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain bZIP_1 PF00170.21 RLN74798.1 - 3.4e-05 23.8 6.7 3.4e-05 23.8 6.7 2.0 2 0 0 2 2 2 1 bZIP transcription factor SUIM_assoc PF16619.5 RLN74798.1 - 0.012 15.6 4.2 0.037 14.1 4.2 1.9 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 KAAG1 PF15354.6 RLN74798.1 - 0.15 12.6 1.8 0.38 11.3 1.8 1.7 1 0 0 1 1 1 0 Kidney-associated antigen 1 DUF775 PF05603.12 RLN74799.1 - 3.8e-16 59.2 1.0 2.3e-12 46.9 0.6 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF775) Tyrosinase PF00264.20 RLN74800.1 - 2.4e-46 158.8 11.2 6.9e-25 88.6 0.2 3.9 3 1 0 3 3 3 2 Common central domain of tyrosinase DUF1925 PF09094.11 RLN74800.1 - 0.0008 19.7 0.4 1.3 9.4 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1925) HSA PF07529.13 RLN74800.1 - 0.0016 18.7 0.0 1.9 8.9 0.0 2.9 3 0 0 3 3 3 2 HSA HMG_box_2 PF09011.10 RLN74800.1 - 0.094 13.3 0.0 9.6 6.9 0.0 2.6 2 0 0 2 2 2 0 HMG-box domain Cauli_VI PF01693.16 RLN74800.1 - 0.12 12.7 0.0 7.3 7.0 0.0 2.7 2 0 0 2 2 2 0 Caulimovirus viroplasmin EpmC PF04315.12 RLN74800.1 - 0.16 11.7 1.4 17 5.0 0.2 2.6 2 0 0 2 2 2 0 Elongation factor P hydroxylase Fucose_iso_C PF02952.17 RLN74800.1 - 0.56 9.9 4.8 1.6 8.4 4.8 1.8 1 0 0 1 1 1 0 L-fucose isomerase, C-terminal domain Tyrosinase PF00264.20 RLN74801.1 - 3.2e-21 76.6 0.1 3.2e-21 76.6 0.1 2.4 2 1 0 2 2 2 1 Common central domain of tyrosinase Tyrosinase PF00264.20 RLN74802.1 - 1.5e-09 38.4 0.9 1.5e-09 38.4 0.9 2.0 2 1 0 2 2 2 1 Common central domain of tyrosinase UPF0489 PF12640.7 RLN74803.1 - 0.065 13.5 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 UPF0489 domain CdiI_2 PF18593.1 RLN74803.1 - 0.096 13.3 0.3 1.6 9.4 0.1 2.4 1 1 1 2 2 2 0 CdiI immunity protein Med3 PF11593.8 RLN74804.1 - 0.75 8.9 4.4 1 8.5 4.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Aminotran_5 PF00266.19 RLN74805.1 - 1.7e-15 56.8 0.0 3.6e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Kelch_5 PF13854.6 RLN74806.1 - 4.4e-24 84.0 1.3 0.00089 19.2 0.0 6.5 5 1 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 RLN74806.1 - 3.5e-17 62.1 4.7 2.4e-07 30.7 0.0 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 RLN74806.1 - 3.8e-17 61.9 4.9 2.9e-07 30.5 0.1 6.1 4 1 1 5 5 5 3 Kelch motif fn3 PF00041.21 RLN74806.1 - 3.6e-16 59.3 1.0 4.1e-06 27.1 0.0 5.4 4 1 0 4 4 4 3 Fibronectin type III domain Kelch_3 PF13415.6 RLN74806.1 - 1.6e-15 57.0 16.8 0.0082 16.4 0.1 8.6 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.25 RLN74806.1 - 7.9e-14 51.0 0.0 0.0012 18.4 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Gly_rich PF12810.7 RLN74806.1 - 4.8e-12 46.3 65.6 1.1e-08 35.3 28.4 2.9 3 0 0 3 3 3 2 Glycine rich protein Kelch_2 PF07646.15 RLN74806.1 - 2.7e-10 39.8 0.1 0.013 15.5 0.0 3.9 3 0 0 3 3 3 3 Kelch motif Tissue_fac PF01108.17 RLN74806.1 - 0.00075 19.3 0.0 0.0027 17.5 0.0 1.9 1 0 0 1 1 1 1 Tissue factor Pur_ac_phosph_N PF16656.5 RLN74806.1 - 0.0045 17.5 1.9 0.15 12.7 0.0 3.7 4 0 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain P_proprotein PF01483.20 RLN74806.1 - 0.11 12.5 0.0 14 5.8 0.0 2.7 2 0 0 2 2 2 0 Proprotein convertase P-domain FYVE PF01363.21 RLN74811.1 - 4.5e-14 52.3 14.8 7.5e-14 51.6 14.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger DUSP PF06337.12 RLN74811.1 - 2.2e-12 47.4 0.0 4e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 DUSP domain FYVE_2 PF02318.16 RLN74811.1 - 2.2 8.5 10.8 4.9 7.4 10.8 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger CAP_GLY PF01302.25 RLN74812.1 - 3.8e-20 71.7 0.2 7.2e-20 70.8 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF3668 PF12416.8 RLN74812.1 - 0.052 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Cep120 protein Apidaecin PF00807.17 RLN74812.1 - 0.43 10.7 2.1 1.6 8.9 2.1 2.0 1 0 0 1 1 1 0 Apidaecin Pkinase_Tyr PF07714.17 RLN74815.1 - 2.7e-33 115.4 0.0 3.8e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN74815.1 - 4.6e-28 98.3 0.0 6.3e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 RLN74815.1 - 0.039 13.7 0.6 0.99 9.2 0.1 2.3 2 0 0 2 2 2 0 Leucine rich repeat APH PF01636.23 RLN74815.1 - 0.073 13.0 0.4 0.16 11.9 0.4 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 RLN74815.1 - 0.25 10.4 0.0 0.4 9.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF667 PF05018.13 RLN74840.1 - 1.8e-87 291.9 2.6 2.2e-86 288.3 2.6 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF667) zf-C2H2 PF00096.26 RLN74841.1 - 7.4e-25 86.0 57.4 8e-05 22.9 0.6 9.3 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN74841.1 - 1.7e-14 53.2 56.7 0.011 16.4 2.6 9.3 9 0 0 9 9 9 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RLN74841.1 - 3.5e-11 43.0 44.7 0.00012 22.4 0.0 9.8 10 1 0 10 10 10 4 Zinc-finger double domain zf-C2H2_8 PF15909.5 RLN74841.1 - 7.4e-07 29.4 30.4 0.0024 18.1 4.9 4.5 1 1 3 5 5 5 4 C2H2-type zinc ribbon zf-met PF12874.7 RLN74841.1 - 4.8e-06 26.8 23.4 0.034 14.6 0.3 6.9 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RLN74841.1 - 0.073 13.4 0.2 0.073 13.4 0.2 7.1 8 0 0 8 8 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RLN74841.1 - 0.26 11.3 34.4 0.3 11.1 0.5 6.7 6 0 0 6 6 6 0 C2H2-type zinc finger GATA PF00320.27 RLN74841.1 - 0.27 10.9 6.9 0.98 9.1 0.1 3.5 4 0 0 4 4 4 0 GATA zinc finger PhnA_Zn_Ribbon PF08274.12 RLN74841.1 - 0.46 10.5 5.3 0.51 10.4 0.2 3.3 3 0 0 3 3 3 0 PhnA Zinc-Ribbon DNA_RNApol_7kD PF03604.13 RLN74841.1 - 1 9.1 5.9 17 5.2 0.1 4.2 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit CHORD PF04968.12 RLN74841.1 - 2.2 9.1 15.2 3.4 8.5 4.3 3.9 3 0 0 3 3 3 0 CHORD zf-Di19 PF05605.12 RLN74841.1 - 6.1 7.2 30.8 0.094 13.0 1.9 5.3 4 1 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-RRPl_C4 PF17026.5 RLN74841.1 - 6.8 6.8 11.0 2.3 8.4 2.4 2.9 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type LMF1 PF06762.14 RLN74842.1 - 2e-76 257.9 7.7 7.4e-44 150.6 0.0 2.1 1 1 1 2 2 2 2 Lipase maturation factor PEPCK_ATP PF01293.20 RLN74843.1 - 7.6e-219 727.1 0.0 9e-219 726.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 RLN74843.1 - 0.11 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SF3b10 PF07189.11 RLN74847.1 - 4.6e-39 132.4 0.0 5.7e-39 132.1 0.0 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) His_biosynth PF00977.21 RLN74849.1 - 3.1e-19 69.3 0.0 1.6e-17 63.8 0.0 2.3 2 1 0 2 2 2 2 Histidine biosynthesis protein OrfB_Zn_ribbon PF07282.11 RLN74850.1 - 1.9e-08 34.1 0.4 5.5e-08 32.6 0.4 1.7 1 0 0 1 1 1 1 Putative transposase DNA-binding domain DUF3827 PF12877.7 RLN74850.1 - 0.065 11.6 3.6 2.5 6.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) GPI2 PF06432.11 RLN74850.1 - 0.43 10.0 1.4 0.71 9.3 1.4 1.2 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase CTP_transf_1 PF01148.20 RLN74853.1 - 4.1e-50 171.0 4.1 5.6e-50 170.6 4.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family RRM_1 PF00076.22 RLN74854.1 - 0.0003 20.5 0.0 0.12 12.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTP_transf_1 PF01148.20 RLN74855.1 - 4.5e-11 43.0 8.4 5.4e-11 42.8 8.4 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family NAGLU PF05089.12 RLN74856.1 - 9e-111 370.0 0.1 1.2e-110 369.6 0.1 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 RLN74856.1 - 3.3e-82 276.0 5.0 4.9e-82 275.4 5.0 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain Peptidase_S9 PF00326.21 RLN74863.1 - 5.1e-51 173.2 0.1 2.1e-50 171.2 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 RLN74863.1 - 1e-38 133.2 0.0 1.4e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Esterase PF00756.20 RLN74863.1 - 0.0041 16.8 0.0 0.0078 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase R2K_2 PF18299.1 RLN74863.1 - 0.0091 15.9 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 2 Myosin_head PF00063.21 RLN74864.1 - 8.1e-217 721.6 0.0 9.8e-217 721.4 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 RLN74864.1 - 1.3e-06 27.7 37.7 0.0047 16.6 4.3 5.2 5 0 0 5 5 5 4 IQ calmodulin-binding motif AAA_16 PF13191.6 RLN74864.1 - 0.02 15.3 0.9 0.092 13.1 0.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 RLN74864.1 - 0.036 14.3 0.0 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 RLN74864.1 - 0.13 11.5 2.0 0.16 11.2 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin Myosin_N PF02736.19 RLN74864.1 - 0.16 11.8 0.2 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Dimer_Tnp_hAT PF05699.14 RLN74868.1 - 2.9e-07 30.2 0.1 6.1e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HgmA PF04209.13 RLN74874.1 - 8.1e-155 515.7 1.3 9.1e-155 515.5 1.3 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase AAA_6 PF12774.7 RLN74875.1 - 3.3e-142 473.3 0.0 4.5e-141 469.6 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN74875.1 - 4.3e-96 322.4 10.8 4.3e-96 322.4 10.8 2.5 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RLN74875.1 - 2.4e-90 302.4 0.0 5.2e-90 301.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 RLN74875.1 - 1.3e-78 264.3 1.9 1.7e-78 263.9 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 RLN74875.1 - 3.1e-73 245.6 0.2 3.1e-73 245.6 0.2 2.8 2 0 0 2 2 1 1 ATP-binding dynein motor region MT PF12777.7 RLN74875.1 - 9.6e-69 232.0 14.6 2.8e-68 230.5 14.6 1.9 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 RLN74875.1 - 3.2e-63 212.5 0.7 2.7e-44 150.8 0.0 5.0 5 0 0 5 5 5 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RLN74875.1 - 2.6e-48 163.9 0.1 2.4e-47 160.8 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RLN74875.1 - 4.1e-37 126.9 0.1 8.2e-34 116.2 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Kelch_5 PF13854.6 RLN74875.1 - 3.1e-33 113.2 9.7 7.7e-09 35.3 0.1 6.8 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 RLN74875.1 - 7.4e-29 99.5 13.6 1.5e-09 37.7 0.8 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 RLN74875.1 - 5.5e-26 90.0 9.9 8e-11 41.8 0.3 6.1 6 0 0 6 6 5 4 Kelch motif Kelch_2 PF07646.15 RLN74875.1 - 1.7e-24 84.8 14.1 1.8e-07 30.9 0.2 6.6 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 RLN74875.1 - 2.3e-22 78.3 13.0 1.9e-07 30.5 0.1 6.4 6 0 0 6 6 6 3 Kelch motif AAA_5 PF07728.14 RLN74875.1 - 3.6e-22 78.9 1.4 2.1e-10 40.7 0.0 7.8 6 2 0 6 6 6 3 AAA domain (dynein-related subfamily) Kelch_3 PF13415.6 RLN74875.1 - 7.4e-22 77.1 19.8 1.4e-06 28.4 0.1 7.4 7 0 0 7 7 6 4 Galactose oxidase, central domain AAA_lid_1 PF17857.1 RLN74875.1 - 4.3e-21 75.0 0.2 2.1e-20 72.8 0.2 2.3 2 0 0 2 2 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 RLN74875.1 - 2.8e-16 59.8 0.3 9.6e-16 58.0 0.3 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Filamin PF00630.19 RLN74875.1 - 4.4e-14 53.1 0.0 1.1e-13 51.9 0.0 1.7 1 0 0 1 1 1 1 Filamin/ABP280 repeat AAA_22 PF13401.6 RLN74875.1 - 1.2e-06 28.9 12.6 0.055 13.7 0.0 6.9 8 0 0 8 8 6 2 AAA domain AAA_18 PF13238.6 RLN74875.1 - 9.2e-06 26.2 6.2 0.098 13.2 0.0 5.1 5 0 0 5 5 4 2 AAA domain AAA_19 PF13245.6 RLN74875.1 - 3e-05 24.4 5.6 0.2 12.0 0.0 4.7 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.6 RLN74875.1 - 0.0002 21.1 4.4 0.79 9.4 0.0 4.1 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 RLN74875.1 - 0.00025 21.4 0.5 3.7 8.0 0.0 3.8 3 0 0 3 3 3 1 RNA helicase AAA_16 PF13191.6 RLN74875.1 - 0.00031 21.2 6.8 0.72 10.2 0.0 6.0 7 0 0 7 7 4 1 AAA ATPase domain TrwB_AAD_bind PF10412.9 RLN74875.1 - 0.00036 19.5 1.2 0.27 10.1 0.1 2.9 3 0 0 3 3 3 2 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 RLN74875.1 - 0.00048 20.6 7.7 4.4 7.8 0.0 5.3 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) TIG PF01833.24 RLN74875.1 - 0.0005 20.1 0.1 0.0014 18.7 0.1 1.8 1 0 0 1 1 1 1 IPT/TIG domain Sigma54_activat PF00158.26 RLN74875.1 - 0.0017 18.1 0.0 0.97 9.1 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain TsaE PF02367.17 RLN74875.1 - 0.0049 16.9 0.3 0.68 9.9 0.0 3.7 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 RLN74875.1 - 0.0051 17.0 6.3 2.8 8.1 0.1 4.7 5 0 0 5 5 4 1 AAA domain AAA_28 PF13521.6 RLN74875.1 - 0.013 15.7 0.0 8.1 6.7 0.0 3.8 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 RLN74875.1 - 0.034 13.5 0.3 30 3.8 0.0 3.4 3 0 0 3 3 3 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 RLN74875.1 - 0.036 13.9 1.7 1.1 9.0 0.0 3.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 RLN74875.1 - 0.058 13.3 1.4 8.8 6.2 0.1 3.7 4 0 0 4 4 3 0 NACHT domain ATPase_2 PF01637.18 RLN74875.1 - 0.077 12.9 5.8 0.17 11.8 0.0 3.9 4 0 0 4 4 2 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 RLN74875.1 - 0.081 12.3 1.2 4.7 6.5 0.0 3.5 4 1 0 4 4 4 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 RLN74875.1 - 0.093 12.8 0.0 1.9 8.6 0.0 3.1 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 RLN74875.1 - 0.15 11.8 0.1 11 5.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 RLN74875.1 - 1.3 8.9 6.0 4.9 7.0 0.1 3.2 3 0 0 3 3 2 0 NTPase AAA_11 PF13086.6 RLN74875.1 - 2.9 7.6 12.2 22 4.7 0.0 4.4 4 0 0 4 4 4 0 AAA domain SNARE PF05739.19 RLN74876.1 - 2.7e-14 52.9 0.0 6.2e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 RLN74876.1 - 0.00084 19.1 1.1 0.68 9.6 0.0 2.3 2 0 0 2 2 2 2 Syntaxin Syntaxin_2 PF14523.6 RLN74876.1 - 0.015 15.7 1.8 0.087 13.2 0.8 2.3 2 0 0 2 2 2 0 Syntaxin-like protein DUF5345 PF17280.2 RLN74876.1 - 0.017 15.1 1.8 0.032 14.2 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5345) FliG_N PF14842.6 RLN74876.1 - 0.036 14.6 1.9 0.72 10.4 0.1 2.8 3 0 0 3 3 3 0 FliG N-terminal domain FUSC PF04632.12 RLN74876.1 - 5.3 5.5 8.7 2.3 6.7 4.7 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family SlyX PF04102.12 RLN74876.1 - 9.3 7.0 12.6 0.85 10.3 0.2 3.2 3 0 0 3 3 3 0 SlyX Glyco_hydro_47 PF01532.20 RLN74877.1 - 2.4e-100 336.6 2.2 7.2e-68 229.5 0.2 2.5 2 1 1 3 3 3 2 Glycosyl hydrolase family 47 Pkinase PF00069.25 RLN74877.1 - 7.2e-60 202.6 0.0 1e-59 202.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN74877.1 - 4.6e-24 85.1 0.0 7.9e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN74877.1 - 0.00015 21.2 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN74877.1 - 0.00097 19.1 0.1 0.0052 16.7 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 RLN74877.1 - 0.042 13.4 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 RLN74877.1 - 0.065 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rhodanese PF00581.20 RLN74878.1 - 0.0014 19.1 0.0 0.0028 18.2 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.20 RLN74878.1 - 0.0033 17.2 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Kinesin PF00225.23 RLN74879.1 - 6.3e-91 304.8 0.5 1.3e-90 303.8 0.5 1.5 1 0 0 1 1 1 1 Kinesin motor domain PHD_2 PF13831.6 RLN74879.1 - 1.1e-18 66.5 10.6 2.4e-09 36.6 0.3 2.9 2 0 0 2 2 2 2 PHD-finger Microtub_bd PF16796.5 RLN74879.1 - 1.8e-18 66.9 5.7 1.5e-17 63.9 0.2 3.1 3 1 0 3 3 3 1 Microtubule binding HgmA PF04209.13 RLN74879.1 - 6.3e-17 61.4 0.2 8.9e-10 37.8 0.0 2.2 2 0 0 2 2 2 2 homogentisate 1,2-dioxygenase PHD PF00628.29 RLN74879.1 - 1.9e-09 37.3 9.4 2.5e-06 27.2 1.4 4.8 5 0 0 5 5 5 2 PHD-finger zf-HC5HC2H_2 PF13832.6 RLN74879.1 - 4.7e-07 29.9 0.3 4.7e-07 29.9 0.3 4.2 3 1 1 4 4 4 1 PHD-zinc-finger like domain C1_1 PF00130.22 RLN74879.1 - 0.0049 16.7 0.3 0.0049 16.7 0.3 5.3 4 1 1 5 5 5 2 Phorbol esters/diacylglycerol binding domain (C1 domain) MMTV_SAg PF01054.17 RLN74879.1 - 0.03 13.9 0.3 0.082 12.4 0.3 1.8 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen DUF1266 PF06889.11 RLN74879.1 - 0.22 11.5 4.1 0.42 10.6 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1266) DUF724 PF05266.14 RLN74879.1 - 4.2 7.2 15.5 0.38 10.6 8.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DER1 PF04511.15 RLN74880.1 - 1.3e-39 136.1 5.9 1.5e-39 135.9 5.9 1.0 1 0 0 1 1 1 1 Der1-like family DUF3397 PF11877.8 RLN74880.1 - 0.09 13.0 7.9 0.027 14.7 2.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3397) DUF2304 PF10066.9 RLN74880.1 - 3.6 7.8 7.1 0.56 10.4 0.7 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2304) Tmemb_cc2 PF10267.9 RLN74881.1 - 3.9 6.5 10.0 0.38 9.9 5.7 1.5 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Ribosomal_60s PF00428.19 RLN74891.1 - 1.2 9.8 9.9 1.4 9.5 9.9 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein MeaB PF03308.16 RLN74903.1 - 5.2e-50 169.9 2.6 1e-49 168.9 2.6 1.5 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 RLN74903.1 - 3.8e-07 29.9 0.2 0.012 15.2 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 RLN74903.1 - 0.002 17.9 0.5 0.0032 17.2 0.5 1.3 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 RLN74903.1 - 0.0026 17.6 0.1 0.0056 16.5 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 RLN74903.1 - 0.0057 17.2 0.0 0.0099 16.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 RLN74903.1 - 0.0087 15.8 0.2 0.018 14.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 RLN74903.1 - 0.015 15.4 0.1 0.043 13.9 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Mg_chelatase PF01078.21 RLN74903.1 - 0.017 14.5 0.1 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 RLN74903.1 - 0.023 14.4 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.18 RLN74903.1 - 0.045 13.5 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.15 RLN74903.1 - 0.057 13.3 0.1 0.09 12.7 0.1 1.3 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 RLN74903.1 - 0.081 13.5 0.1 0.28 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 RLN74903.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 RLN74903.1 - 0.11 12.2 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.6 RLN74903.1 - 0.28 11.7 0.0 0.46 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain PDZ_6 PF17820.1 RLN74904.1 - 3.3e-05 23.6 0.0 8.8e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RLN74904.1 - 0.083 13.2 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 PDZ domain RabGAP-TBC PF00566.18 RLN74905.1 - 2.2e-10 40.5 0.4 7.3e-10 38.9 0.1 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Pkinase PF00069.25 RLN74906.1 - 1.9e-49 168.4 0.0 2.6e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN74906.1 - 2.1e-45 155.0 0.0 2.8e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN74906.1 - 0.0038 16.6 0.0 0.0055 16.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN74906.1 - 0.0053 16.7 0.0 0.1 12.5 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Mito_carr PF00153.27 RLN74907.1 - 5.7e-68 224.9 2.7 7.3e-23 80.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 RLN74907.1 - 0.025 13.7 2.6 0.053 12.7 0.1 2.7 4 1 1 5 5 5 0 Gammaproteobacterial serine protease Ank_2 PF12796.7 RLN74908.1 - 6.2e-25 87.6 7.7 1.7e-13 50.9 0.3 4.4 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN74908.1 - 2.5e-16 59.5 8.6 0.0002 21.5 0.5 5.9 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN74908.1 - 1.2e-13 49.9 11.4 0.0027 18.1 0.2 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 RLN74908.1 - 1.8e-12 47.5 7.7 3.1e-05 24.4 0.3 5.4 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN74908.1 - 8.7e-10 38.6 20.8 0.0012 19.2 0.1 7.6 9 0 0 9 9 9 2 Ankyrin repeat PHD PF00628.29 RLN74908.1 - 4.3e-06 26.5 5.9 4.3e-06 26.5 5.9 2.6 2 0 0 2 2 2 1 PHD-finger HECT PF00632.25 RLN74908.1 - 0.00018 21.1 0.0 0.0022 17.5 0.0 2.4 2 1 0 2 2 2 1 HECT-domain (ubiquitin-transferase) CDC27 PF09507.10 RLN74908.1 - 0.13 11.6 20.7 0.21 11.0 20.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 RLN74908.1 - 5.5 5.2 13.5 8.5 4.5 13.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_72 PF03198.14 RLN74909.1 - 0.00053 19.3 0.1 0.00078 18.8 0.1 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Nucleoporin_FG PF13634.6 RLN74916.1 - 0.00052 20.8 0.0 0.00088 20.1 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin FG repeat region DHC_N1 PF08385.12 RLN74917.1 - 0.006 15.3 0.7 0.011 14.4 0.7 1.4 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 EspB_PE PF18625.1 RLN74917.1 - 0.011 16.2 0.3 0.095 13.2 0.1 2.6 1 1 0 1 1 1 0 ESX-1 secreted protein B PE domain PMEI PF04043.15 RLN74917.1 - 0.069 13.5 1.3 0.11 12.8 1.3 1.4 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Occludin_ELL PF07303.13 RLN74917.1 - 0.23 12.2 4.6 4.5 8.1 0.8 3.0 2 1 1 3 3 3 0 Occludin homology domain DUF1451 PF07295.11 RLN74917.1 - 0.69 9.9 5.4 0.5 10.4 2.5 2.1 2 1 0 2 2 2 0 Zinc-ribbon containing domain Cytochrom_B562 PF07361.11 RLN74917.1 - 8.1 7.2 12.1 6.5 7.5 7.4 2.6 1 1 0 2 2 2 0 Cytochrome b562 Ank_2 PF12796.7 RLN74918.1 - 5e-49 164.8 13.6 9.6e-15 54.9 0.8 6.0 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN74918.1 - 8.8e-29 96.4 15.1 0.057 14.0 0.0 11.8 12 0 0 12 12 12 8 Ankyrin repeat Ank_4 PF13637.6 RLN74918.1 - 8.3e-28 96.4 17.0 4.1e-09 36.8 0.2 8.2 4 3 7 11 11 11 9 Ankyrin repeats (many copies) Ank PF00023.30 RLN74918.1 - 1e-25 89.0 24.3 0.0076 16.7 0.1 11.6 11 1 1 12 12 12 8 Ankyrin repeat Ank_5 PF13857.6 RLN74918.1 - 1.3e-19 70.0 23.6 0.00027 21.2 0.1 10.0 2 2 7 10 10 10 8 Ankyrin repeats (many copies) F-box PF00646.33 RLN74918.1 - 0.0022 17.8 0.3 0.0058 16.5 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 RLN74918.1 - 0.56 10.1 2.9 0.4 10.6 0.5 2.0 2 0 0 2 2 2 0 F-box-like TPR_1 PF00515.28 RLN74919.1 - 1.1e-18 66.2 0.3 8.6e-08 31.7 0.0 5.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN74919.1 - 7.8e-18 63.1 8.5 1.1e-08 34.5 0.1 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 RLN74919.1 - 1.2e-16 59.8 0.7 0.029 14.7 0.0 5.1 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 RLN74919.1 - 1.4e-15 57.6 23.1 1.1e-07 32.3 4.8 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 RLN74919.1 - 4.5e-15 55.7 16.1 1e-08 35.3 5.2 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 RLN74919.1 - 1.2e-14 53.8 22.5 2.5e-06 27.8 3.4 5.2 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN74919.1 - 1.8e-14 52.6 6.7 1.1e-05 25.0 0.3 4.5 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 RLN74919.1 - 2.1e-13 50.6 11.7 1.7e-09 38.0 2.5 4.0 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN74919.1 - 1.9e-12 46.6 0.7 0.00047 19.8 0.1 4.8 4 1 2 6 6 6 3 TPR repeat TPR_8 PF13181.6 RLN74919.1 - 2e-10 40.0 0.3 5.3e-05 23.1 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN74919.1 - 3e-09 36.4 12.7 0.0048 16.7 0.3 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 RLN74919.1 - 9.7e-09 35.3 16.3 4.3e-08 33.2 8.3 3.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 RLN74919.1 - 1.2e-07 31.3 6.5 0.00013 21.3 0.2 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat Wzy_C_2 PF11846.8 RLN74919.1 - 6.3e-07 29.5 6.6 0.011 15.7 0.9 3.2 1 1 2 3 3 3 3 Virulence factor membrane-bound polymerase, C-terminal TPR_4 PF07721.14 RLN74919.1 - 4.1e-06 26.9 32.3 0.038 14.6 0.2 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_20 PF14561.6 RLN74919.1 - 6.5e-05 23.2 11.2 0.21 11.9 1.3 4.6 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 RLN74919.1 - 9.2e-05 22.8 11.6 0.016 15.8 0.1 4.9 6 0 0 6 6 6 2 Tetratricopeptide repeat BTAD PF03704.17 RLN74919.1 - 0.00024 21.6 11.1 0.00024 21.6 11.1 3.0 1 1 2 3 3 3 1 Bacterial transcriptional activator domain TPR_MalT PF17874.1 RLN74919.1 - 0.016 14.6 7.1 0.026 13.9 0.5 2.7 1 1 1 3 3 3 0 MalT-like TPR region ANAPC3 PF12895.7 RLN74919.1 - 0.051 13.8 0.8 0.66 10.2 0.1 2.7 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4810 PF16068.5 RLN74919.1 - 0.067 13.7 0.2 1.2e+02 3.3 0.0 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF4810) DUF3856 PF12968.7 RLN74919.1 - 0.15 12.1 2.1 30 4.7 0.8 3.6 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_21 PF09976.9 RLN74919.1 - 0.23 11.2 2.1 0.41 10.3 1.7 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain Cnd2 PF05786.14 RLN74920.1 - 1.1e-76 259.1 42.7 1.1e-76 259.1 42.7 5.4 2 2 1 3 3 3 2 Condensin complex subunit 2 CNDH2_N PF06278.11 RLN74920.1 - 0.0002 21.5 0.0 0.0002 21.5 0.0 3.6 3 0 0 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Pkinase_Tyr PF07714.17 RLN74928.1 - 2.3e-44 151.6 0.0 4.4e-44 150.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN74928.1 - 2.6e-38 131.9 0.0 5.7e-38 130.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.23 RLN74928.1 - 9.5e-28 95.4 12.2 0.0011 19.0 0.0 9.6 9 0 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN74928.1 - 9.2e-07 29.2 11.2 0.37 11.3 0.6 5.3 4 1 1 5 5 4 3 HEAT-like repeat Arm_2 PF04826.13 RLN74928.1 - 2.5e-05 23.9 0.3 0.051 13.0 0.0 3.2 2 1 0 3 3 3 2 Armadillo-like V-ATPase_H_N PF03224.14 RLN74928.1 - 0.00012 21.5 0.1 0.16 11.2 0.0 2.7 1 1 0 2 2 2 2 V-ATPase subunit H HEAT_2 PF13646.6 RLN74928.1 - 0.00019 21.8 23.7 0.021 15.2 2.3 5.5 3 1 5 8 8 8 6 HEAT repeats Atx10homo_assoc PF09759.9 RLN74928.1 - 0.00029 20.8 0.2 2.2 8.4 0.0 4.2 2 1 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.8 RLN74928.1 - 0.0023 17.9 5.9 0.6 10.1 0.1 4.4 3 1 1 4 4 4 1 Myosin-binding striated muscle assembly central ABC1 PF03109.16 RLN74928.1 - 0.0025 18.0 0.0 0.0082 16.3 0.0 1.9 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 RLN74928.1 - 0.022 14.7 0.1 0.068 13.1 0.1 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family DZR PF12773.7 RLN74928.1 - 0.12 12.4 0.3 0.24 11.4 0.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 RLN74928.1 - 0.12 13.1 0.1 0.27 12.0 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon family zinc-ribbon_6 PF10005.9 RLN74928.1 - 0.28 11.9 2.1 0.68 10.7 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain HEAT PF02985.22 RLN74928.1 - 0.54 10.7 9.6 32 5.1 0.1 6.1 5 0 0 5 5 5 0 HEAT repeat Phi_1 PF04674.12 RLN74933.1 - 0.12 11.7 0.1 0.16 11.3 0.1 1.1 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region Ribosomal_L22 PF00237.19 RLN74934.1 - 3.1e-17 62.7 0.6 3.9e-17 62.4 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e LRR_6 PF13516.6 RLN74935.1 - 8.6e-05 22.3 0.2 4.9 7.5 0.3 4.9 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 RLN74935.1 - 0.00049 20.4 5.9 1 9.9 0.1 4.4 2 1 4 6 6 6 4 Leucine Rich repeats (2 copies) MutS_V PF00488.21 RLN74936.1 - 4.3e-75 251.9 0.0 1e-74 250.7 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 RLN74936.1 - 3.2e-34 118.8 0.2 1.7e-33 116.5 0.1 2.3 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 RLN74936.1 - 1e-28 99.8 0.1 2.2e-28 98.8 0.1 1.5 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 RLN74936.1 - 2.9e-16 59.6 0.2 9.7e-16 57.9 0.2 2.0 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 RLN74936.1 - 3.5e-09 37.1 0.5 3.3e-08 33.9 0.0 3.0 3 1 0 3 3 3 1 MutS domain II AAA_29 PF13555.6 RLN74936.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_transf_28 PF03033.20 RLN74941.1 - 3.3e-27 95.2 0.5 3.6e-20 72.4 0.4 3.4 2 1 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 RLN74941.1 - 1.1e-05 24.5 0.6 9.2e-05 21.4 0.0 2.6 3 0 0 3 3 3 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 RLN74941.1 - 0.0066 16.8 0.0 0.031 14.6 0.0 2.2 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain SIS_2 PF13580.6 RLN74941.1 - 0.11 12.5 0.0 0.38 10.8 0.0 1.9 1 0 0 1 1 1 0 SIS domain SNF2_N PF00176.23 RLN74945.1 - 3.4e-62 210.2 0.4 6.5e-62 209.3 0.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 RLN74945.1 - 1.9e-21 75.7 0.0 4.9e-10 39.2 0.0 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 RLN74945.1 - 6e-17 62.0 0.0 1.4e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN74945.1 - 2.6e-08 34.1 0.0 1.1e-07 32.0 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RLN74945.1 - 6.7e-06 26.0 0.0 2.1e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 RLN74945.1 - 8.4e-05 21.9 0.0 8.4e-05 21.9 0.0 2.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 CHDCT2 PF08074.11 RLN74945.1 - 0.08 13.1 0.0 0.08 13.1 0.0 3.5 4 0 0 4 4 4 0 CHDCT2 (NUC038) domain AAA_22 PF13401.6 RLN74945.1 - 0.082 13.2 0.8 0.36 11.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain NHL PF01436.21 RLN74946.1 - 9.5e-25 85.3 10.2 8.3e-08 31.9 0.2 8.3 7 1 0 7 7 7 5 NHL repeat LCCL PF03815.19 RLN74946.1 - 2.6e-14 53.1 0.0 2e-13 50.2 0.0 2.6 1 0 0 1 1 1 1 LCCL domain EGF_2 PF07974.13 RLN74946.1 - 3.5e-13 49.7 191.9 0.00082 19.7 9.6 14.5 12 1 1 13 13 13 11 EGF-like domain SGL PF08450.12 RLN74946.1 - 3.2e-09 36.8 0.8 0.014 15.0 0.0 3.6 3 0 0 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region Phage_holin_2_4 PF16082.5 RLN74946.1 - 0.063 13.0 0.7 0.21 11.4 0.7 1.9 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like hEGF PF12661.7 RLN74946.1 - 2.3 9.0 147.5 0.25 12.0 6.5 14.6 13 0 0 13 13 13 0 Human growth factor-like EGF Pkinase PF00069.25 RLN74951.1 - 0.0033 16.8 0.0 0.0053 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 RLN74951.1 - 0.035 13.5 0.0 0.088 12.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ubiquitin PF00240.23 RLN74965.1 - 2.2e-07 30.5 0.5 5.8e-07 29.2 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 RLN74965.1 - 7.1e-05 23.2 0.1 0.00031 21.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 RLN74965.1 - 0.0034 17.2 0.4 0.022 14.6 0.4 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 RLN74965.1 - 0.017 15.1 0.3 0.12 12.4 0.2 1.9 1 1 1 2 2 2 0 Ubiquitin-like domain RAWUL PF16207.5 RLN74965.1 - 0.054 14.2 0.0 0.07 13.8 0.0 1.2 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Pkinase_Tyr PF07714.17 RLN74966.1 - 2.5e-28 99.1 0.0 2.2e-18 66.5 0.1 3.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN74966.1 - 9.5e-20 71.0 0.0 1.4e-17 63.9 0.1 2.3 1 1 0 2 2 2 2 Protein kinase domain Cofilin_ADF PF00241.20 RLN74966.1 - 3e-05 23.8 0.0 0.075 12.8 0.0 2.5 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Ubiquitin_2 PF14560.6 RLN74966.1 - 0.013 15.9 0.0 0.027 14.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain tRNA-synt_1c PF00749.21 RLN74967.1 - 1.6e-59 201.4 0.1 1.2e-36 126.2 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain PALP PF00291.25 RLN74968.1 - 3.9e-40 138.1 0.5 6.3e-26 91.5 0.1 2.5 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme COG2 PF06148.11 RLN74968.1 - 7.3e-25 87.6 4.3 7.3e-25 87.6 4.3 2.6 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 RLN74968.1 - 6.9e-12 45.9 0.2 6.9e-12 45.9 0.2 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) MutS_III PF05192.18 RLN74968.1 - 0.041 14.1 4.9 0.017 15.3 0.7 2.5 2 1 0 2 2 2 0 MutS domain III AAA_33 PF13671.6 RLN74969.1 - 2.1e-20 73.3 0.7 3.9e-20 72.5 0.1 1.8 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 RLN74969.1 - 3.5e-12 46.4 0.0 5.4e-11 42.4 0.0 2.0 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 RLN74969.1 - 0.00025 21.6 0.0 0.00054 20.5 0.0 1.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN74969.1 - 0.0052 17.2 1.4 0.012 16.0 1.4 2.0 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 RLN74969.1 - 0.007 15.7 0.0 0.035 13.4 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 RLN74969.1 - 0.01 16.1 0.1 0.026 14.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 RLN74969.1 - 0.017 15.5 0.0 0.047 14.1 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 RLN74969.1 - 0.029 13.5 0.0 0.061 12.5 0.0 1.5 1 1 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.6 RLN74969.1 - 0.033 14.4 1.8 0.2 11.9 0.0 2.6 2 1 1 3 3 3 0 AAA domain CPT PF07931.12 RLN74969.1 - 0.036 13.9 0.0 0.087 12.7 0.0 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein APS_kinase PF01583.20 RLN74969.1 - 0.055 13.4 0.1 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase 6PF2K PF01591.18 RLN74969.1 - 0.095 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_23 PF13476.6 RLN74969.1 - 0.1 13.1 0.1 0.17 12.4 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 RLN74969.1 - 0.15 12.4 0.8 2.9 8.3 0.1 2.8 2 1 0 2 2 2 0 AAA domain DUF4953 PF16313.5 RLN74970.1 - 1.6e-62 211.6 0.0 2.3e-62 211.1 0.0 1.2 1 0 0 1 1 1 1 Met-zincin DUF5117 PF17148.4 RLN74970.1 - 1e-10 41.8 0.0 2.4e-08 34.1 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF5117) Reprolysin_5 PF13688.6 RLN74970.1 - 0.00041 20.6 0.5 0.00041 20.6 0.5 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 RLN74970.1 - 0.0014 18.3 1.0 0.0029 17.3 0.1 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 RLN74970.1 - 0.0041 17.0 0.4 0.096 12.5 0.0 2.4 2 0 0 2 2 2 1 Matrixin Peptidase_M66 PF10462.9 RLN74970.1 - 0.012 14.6 0.1 0.02 13.9 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_2 PF13574.6 RLN74970.1 - 0.014 15.3 0.2 0.041 13.8 0.1 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 RLN74970.1 - 0.015 15.2 0.1 0.031 14.2 0.1 1.5 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 RLN74970.1 - 0.021 15.3 0.1 0.021 15.3 0.1 2.3 3 0 0 3 3 3 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 RLN74970.1 - 0.054 13.1 0.4 2.7 7.6 0.2 2.4 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) DUF5325 PF17259.2 RLN74970.1 - 0.15 12.0 0.2 0.31 11.0 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5325) Cpn60_TCP1 PF00118.24 RLN74971.1 - 1.5e-22 80.0 0.1 5.5e-22 78.0 0.1 1.9 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 RLN74971.1 - 3.7e-17 62.2 10.6 3.7e-17 62.2 10.6 2.3 2 1 0 2 2 2 1 FYVE zinc finger Mannosyl_trans3 PF11051.8 RLN74981.1 - 9.1e-25 87.5 0.0 1.3e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative WD40 PF00400.32 RLN75008.1 - 1.4e-21 76.3 1.2 0.0023 18.7 0.0 7.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN75008.1 - 1.4e-05 25.3 0.0 0.067 13.5 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RLN75008.1 - 0.003 17.5 0.0 0.0054 16.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A LisH_TPL PF17814.1 RLN75008.1 - 0.0041 16.7 0.0 0.0096 15.6 0.0 1.7 1 0 0 1 1 1 1 LisH-like dimerisation domain LisH PF08513.11 RLN75008.1 - 0.011 15.6 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 0 LisH SAP30_Sin3_bdg PF13867.6 RLN75009.1 - 8.5e-14 51.6 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 PHD PF00628.29 RLN75009.1 - 9.5e-06 25.4 5.7 9.5e-06 25.4 5.7 1.7 2 0 0 2 2 2 1 PHD-finger Macoilin PF09726.9 RLN75009.1 - 0.62 8.6 10.3 0.64 8.5 10.3 1.1 1 0 0 1 1 1 0 Macoilin family Pol_alpha_B_N PF08418.10 RLN75009.1 - 5.7 6.8 10.5 0.15 12.0 4.4 1.4 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Presenilin PF01080.17 RLN75009.1 - 5.8 5.6 6.0 8.9 5.0 6.0 1.3 1 0 0 1 1 1 0 Presenilin Mito_carr PF00153.27 RLN75010.1 - 1.2e-50 169.4 1.2 1.7e-16 59.9 0.5 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein PX PF00787.24 RLN75011.1 - 1.1e-09 38.2 0.0 1.8e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 PX domain ETAA1 PF15350.6 RLN75011.1 - 0.022 13.1 0.2 0.027 12.8 0.2 1.0 1 0 0 1 1 1 0 Ewing's tumour-associated antigen 1 homologue OTCace_N PF02729.21 RLN75022.1 - 1.5e-38 132.1 0.0 4.5e-38 130.6 0.0 1.7 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 RLN75022.1 - 1.2e-37 129.4 0.1 1.6e-37 129.0 0.1 1.1 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Peptidase_M20 PF01546.28 RLN75023.1 - 1.7e-19 70.3 1.0 3.7e-17 62.7 0.3 2.8 3 0 0 3 3 3 2 Peptidase family M20/M25/M40 M20_dimer PF07687.14 RLN75023.1 - 1.8e-10 40.7 0.3 8.4e-10 38.5 0.0 2.2 2 0 0 2 2 2 1 Peptidase dimerisation domain CENP-B_N PF04218.13 RLN75023.1 - 0.00011 21.8 0.7 0.0003 20.4 0.7 1.7 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_32 PF13565.6 RLN75023.1 - 0.021 15.4 0.0 0.057 14.0 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_11 PF08279.12 RLN75023.1 - 0.078 12.9 0.2 0.16 11.9 0.2 1.5 1 0 0 1 1 1 0 HTH domain HTH_24 PF13412.6 RLN75023.1 - 0.14 11.8 0.1 0.3 10.7 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 RLN75023.1 - 0.14 12.0 0.1 0.33 10.8 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain SurA_N PF09312.11 RLN75023.1 - 0.24 11.5 2.5 0.25 11.4 0.3 2.2 2 0 0 2 2 2 0 SurA N-terminal domain dCMP_cyt_deam_1 PF00383.23 RLN75024.1 - 3.7e-05 23.5 0.4 0.00067 19.5 0.4 2.8 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 RLN75024.1 - 0.063 13.0 0.8 0.3 10.9 1.3 1.7 2 0 0 2 2 2 0 MafB19-like deaminase DUF2401 PF10287.9 RLN75025.1 - 2.6e-60 203.9 0.5 4.3e-60 203.2 0.5 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 RLN75025.1 - 2.6e-10 40.6 0.1 2.4e-09 37.5 0.0 2.8 2 1 1 3 3 3 1 Glycine-rich protein domain (DUF2403) FAM70 PF14967.6 RLN75025.1 - 2.1 7.7 6.5 3.6 7.0 6.5 1.3 1 0 0 1 1 1 0 FAM70 protein zf-C3HC4 PF00097.25 RLN75026.1 - 1.2e-08 34.7 10.3 1.2e-08 34.7 10.3 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN75026.1 - 1.4e-07 31.5 9.7 1.7e-07 31.1 8.3 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 RLN75026.1 - 3.4e-07 30.5 11.4 3.4e-07 30.5 11.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 RLN75026.1 - 2.6e-06 27.2 7.1 2.6e-06 27.2 7.1 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN75026.1 - 9.6e-06 25.4 13.7 9.6e-06 25.4 13.7 2.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN75026.1 - 2.1e-05 24.7 6.1 7.8e-05 22.9 6.1 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RLN75026.1 - 2.3e-05 24.3 8.8 2.3e-05 24.3 8.8 2.4 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 RLN75026.1 - 6.1e-05 23.1 12.7 6.1e-05 23.1 12.7 2.2 3 0 0 3 3 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RLN75026.1 - 0.0006 19.6 9.0 0.037 13.9 9.7 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 RLN75026.1 - 0.0022 18.0 2.2 0.0045 17.0 2.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PWI PF01480.17 RLN75026.1 - 0.0023 18.2 0.2 0.015 15.6 0.0 2.1 2 0 0 2 2 2 1 PWI domain zf-RING_6 PF14835.6 RLN75026.1 - 0.012 15.4 5.1 0.038 13.8 5.1 1.9 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 RLN75026.1 - 0.037 13.9 6.0 0.12 12.3 6.1 1.8 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit GAGA PF09237.11 RLN75026.1 - 0.34 10.7 0.1 0.34 10.7 0.1 2.8 3 0 0 3 3 2 0 GAGA factor Zn-C2H2_12 PF18112.1 RLN75026.1 - 0.6 10.6 0.1 0.6 10.6 0.1 2.9 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-MIZ PF02891.20 RLN75026.1 - 2.8 7.8 14.4 0.59 9.9 10.4 2.0 2 1 0 2 2 2 0 MIZ/SP-RING zinc finger DEAD PF00270.29 RLN75027.1 - 2e-43 148.2 0.0 2.4e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 RLN75027.1 - 9.3e-08 32.3 0.0 1.1e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit OMPdecase PF00215.24 RLN75027.1 - 0.023 14.3 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family UvrD-helicase PF00580.21 RLN75027.1 - 0.15 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Carn_acyltransf PF00755.20 RLN75032.1 - 1.4e-91 308.0 0.0 1.6e-91 307.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase G6PD_C PF02781.16 RLN75041.1 - 3.7e-109 364.4 0.0 4.6e-109 364.1 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 RLN75041.1 - 1e-56 192.4 0.0 1.5e-56 191.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain BRO1 PF03097.18 RLN75043.1 - 1.6e-100 336.6 0.2 5.1e-100 335.0 0.0 1.8 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 RLN75043.1 - 8.8e-62 209.0 11.0 8.8e-62 209.0 11.0 2.2 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV Ribosomal_S13 PF00416.22 RLN75043.1 - 0.1 13.0 0.3 0.1 13.0 0.3 2.3 3 0 0 3 3 3 0 Ribosomal protein S13/S18 FbpA PF05833.11 RLN75043.1 - 0.1 11.4 8.3 0.89 8.2 8.3 2.4 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DOT1 PF08123.13 RLN75044.1 - 8.1e-25 87.6 0.0 1.3e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 RLN75044.1 - 1.3e-06 28.0 0.0 2.7e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 RLN75044.1 - 7.9e-06 26.5 0.0 2.7e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN75044.1 - 0.00032 20.5 0.0 0.00078 19.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN75044.1 - 0.00088 19.9 0.0 0.033 14.8 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN75044.1 - 0.014 16.1 0.0 0.034 14.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 RLN75044.1 - 0.027 14.2 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 RLN75044.1 - 0.029 14.2 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 RLN75044.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 RLN75044.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Peroxin-3 PF04882.12 RLN75045.1 - 1.3e-11 44.2 3.0 1.7e-07 30.6 0.4 3.2 1 1 1 2 2 2 2 Peroxin-3 WD-3 PF09765.9 RLN75045.1 - 0.024 14.0 0.4 0.05 12.9 0.1 1.6 2 0 0 2 2 2 0 WD-repeat region Csm2_III-A PF03750.13 RLN75045.1 - 0.039 14.8 0.3 7 7.5 0.1 3.2 3 0 0 3 3 3 0 Csm2 Type III-A Nudc_N PF14050.6 RLN75046.1 - 1.9e-20 72.6 0.8 2.8e-20 72.0 0.2 1.6 2 0 0 2 2 2 1 N-terminal conserved domain of Nudc. CS PF04969.16 RLN75046.1 - 8.7e-08 33.1 0.0 1.3e-07 32.5 0.0 1.2 1 0 0 1 1 1 1 CS domain SecA_SW PF07516.13 RLN75046.1 - 0.043 13.9 0.1 0.067 13.2 0.1 1.2 1 0 0 1 1 1 0 SecA Wing and Scaffold domain RPAP2_Rtr1 PF04181.13 RLN75053.1 - 5.2e-13 49.1 0.5 8.4e-13 48.5 0.5 1.3 1 0 0 1 1 1 1 Rtr1/RPAP2 family zf-FCS PF06467.14 RLN75053.1 - 0.092 12.7 0.9 0.2 11.7 0.9 1.7 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif ECH_1 PF00378.20 RLN75054.1 - 1.3e-19 70.5 0.0 1.5e-19 70.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RLN75054.1 - 5.4e-13 49.1 0.0 6.2e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase COMM_domain PF07258.14 RLN75064.1 - 4.3e-11 42.8 0.1 7.1e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 COMM domain Protoglobin PF11563.8 RLN75064.1 - 0.056 13.3 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Protoglobin IQ PF00612.27 RLN75065.1 - 0.00017 21.1 32.7 0.011 15.5 0.6 5.8 5 1 1 6 6 6 3 IQ calmodulin-binding motif Pkinase PF00069.25 RLN75067.1 - 2.2e-30 105.9 0.0 3.9e-30 105.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN75067.1 - 1e-12 47.9 0.0 1.2e-11 44.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN75067.1 - 5.4e-05 22.7 0.0 0.00025 20.5 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN75067.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family COG7 PF10191.9 RLN75068.1 - 3e-56 191.1 0.0 2.2e-46 158.5 0.0 2.3 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) Gly_transf_sug PF04488.15 RLN75069.1 - 1.6e-11 44.6 0.0 2.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 RLN75069.1 - 0.00098 18.6 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein ATP-grasp_4 PF13535.6 RLN75070.1 - 3e-23 82.2 0.0 1.2e-11 44.4 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain ATP-grasp_3 PF02655.14 RLN75070.1 - 4.2e-14 52.9 0.0 2e-06 27.9 0.0 2.6 2 1 0 2 2 2 2 ATP-grasp domain LAL_C2 PF18603.1 RLN75070.1 - 7.4e-14 51.7 0.0 1.1e-07 31.9 0.0 3.1 3 0 0 3 3 3 2 L-amino acid ligase C-terminal domain 2 ATPgrasp_Ter PF15632.6 RLN75070.1 - 2.6e-09 36.9 0.1 0.0088 15.8 0.0 4.5 3 2 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 RLN75070.1 - 1.7e-08 34.5 0.0 0.00017 21.4 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 RLN75070.1 - 0.0019 17.8 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 RLN75070.1 - 0.02 14.3 0.0 0.36 10.2 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain Fibritin_C PF07921.12 RLN75070.1 - 0.15 12.2 0.0 13 6.0 0.0 2.4 2 0 0 2 2 2 0 Fibritin C-terminal region PLDc_2 PF13091.6 RLN75081.1 - 1.8e-17 63.5 0.0 3e-13 49.8 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 RLN75081.1 - 1.2e-08 34.8 4.9 5.4e-05 23.2 0.3 3.1 2 1 0 2 2 2 2 Phospholipase D Active site motif MFS_1 PF07690.16 RLN75082.1 - 3.8e-15 55.7 36.5 4.6e-10 39.0 15.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RLN75082.1 - 8e-13 47.7 22.8 1.3e-12 47.1 8.4 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_2 PF13347.6 RLN75083.1 - 1.2e-10 40.6 26.1 2.9e-10 39.3 25.9 1.8 1 1 0 1 1 1 1 MFS/sugar transport protein BT1 PF03092.16 RLN75083.1 - 0.0019 16.5 0.2 0.0019 16.5 0.2 2.3 2 0 0 2 2 2 1 BT1 family MFS_2 PF13347.6 RLN75084.1 - 9.5e-09 34.3 9.4 9.5e-09 34.3 9.4 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein TMEM240 PF15207.6 RLN75084.1 - 0.025 14.3 0.3 0.27 10.9 0.0 2.3 2 0 0 2 2 2 0 TMEM240 family MFS_2 PF13347.6 RLN75085.1 - 2.6e-11 42.8 12.5 2.6e-11 42.8 12.5 2.7 2 1 1 3 3 3 1 MFS/sugar transport protein MFS_1 PF07690.16 RLN75086.1 - 3e-10 39.6 42.2 3.4e-07 29.5 14.1 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RLN75086.1 - 1.6e-08 33.6 11.6 1.6e-08 33.6 11.6 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein BT1 PF03092.16 RLN75086.1 - 0.012 13.9 0.2 0.012 13.9 0.2 2.3 2 0 0 2 2 2 0 BT1 family HSP70 PF00012.20 RLN75087.1 - 3.5e-69 233.6 0.0 4.2e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Arm PF00514.23 RLN75096.1 - 2.2e-44 148.2 11.7 1.7e-06 27.8 0.0 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat 2-Hacid_dh_C PF02826.19 RLN75096.1 - 4.1e-43 146.8 0.0 8.5e-43 145.8 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Prenyltrans PF00432.21 RLN75096.1 - 2.5e-25 87.9 24.4 1.8e-10 40.4 0.3 6.2 7 0 0 7 7 7 4 Prenyltransferase and squalene oxidase repeat HEAT_EZ PF13513.6 RLN75096.1 - 2.6e-09 37.4 17.8 0.0009 19.7 0.0 7.0 4 2 5 9 9 9 4 HEAT-like repeat Arm_2 PF04826.13 RLN75096.1 - 1.1e-07 31.6 0.0 0.0086 15.6 0.0 3.7 1 1 3 4 4 4 2 Armadillo-like Atx10homo_assoc PF09759.9 RLN75096.1 - 4.3e-07 29.9 4.2 0.17 12.0 0.0 6.2 3 2 4 7 7 7 2 Spinocerebellar ataxia type 10 protein domain NAD_binding_2 PF03446.15 RLN75096.1 - 2.2e-05 24.7 0.0 5.5e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase HEAT_2 PF13646.6 RLN75096.1 - 0.0001 22.7 28.1 0.00046 20.5 1.7 7.5 4 2 5 9 9 9 3 HEAT repeats HEAT PF02985.22 RLN75096.1 - 0.00042 20.3 7.5 91 3.7 0.0 8.6 9 0 0 9 9 9 0 HEAT repeat Aconitase_B_N PF11791.8 RLN75096.1 - 0.066 13.3 2.5 0.8 9.8 0.1 3.5 3 1 1 4 4 4 0 Aconitate B N-terminal domain F420_oxidored PF03807.17 RLN75096.1 - 0.068 13.8 0.0 0.28 11.8 0.0 2.1 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HEAT_PBS PF03130.16 RLN75096.1 - 0.49 11.2 39.7 0.9 10.4 0.2 11.2 12 0 0 12 12 12 0 PBS lyase HEAT-like repeat HABP4_PAI-RBP1 PF04774.15 RLN75097.1 - 4.3 8.2 13.1 1.3 9.8 5.9 2.9 3 0 0 3 3 3 0 Hyaluronan / mRNA binding family ADH_zinc_N_2 PF13602.6 RLN75098.1 - 0.00087 20.3 0.0 0.00091 20.3 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase cNMP_binding PF00027.29 RLN75110.1 - 1.7e-07 31.2 0.0 3.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain RINGv PF12906.7 RLN75111.1 - 2.3e-13 50.1 6.8 9.2e-13 48.1 6.8 2.1 1 1 0 1 1 1 1 RING-variant domain FHA PF00498.26 RLN75111.1 - 2.6e-13 50.1 0.1 2.6e-11 43.7 0.0 2.5 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 RLN75111.1 - 1.1e-06 28.8 0.0 3.9e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_2 PF13639.6 RLN75111.1 - 0.011 16.0 7.5 0.38 11.1 8.7 2.6 1 1 1 2 2 2 0 Ring finger domain Chromo PF00385.24 RLN75117.1 - 0.009 15.9 0.5 0.014 15.3 0.5 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ABC_membrane PF00664.23 RLN75118.1 - 2e-64 217.9 36.4 5.1e-37 128.0 8.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN75118.1 - 1e-30 107.0 0.1 2.8e-19 70.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 RLN75118.1 - 2.3e-07 30.9 0.3 0.018 15.1 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 RLN75118.1 - 2.7e-05 24.1 1.7 0.84 9.4 0.6 3.3 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN75118.1 - 3.2e-05 23.6 0.2 0.11 12.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN75118.1 - 0.00013 21.9 0.9 0.074 13.0 0.2 2.8 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 RLN75118.1 - 0.00034 21.2 0.3 1.4 9.4 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 RLN75118.1 - 0.0007 20.0 0.1 0.046 14.1 0.0 3.3 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 RLN75118.1 - 0.00072 19.7 0.3 0.037 14.1 0.0 2.5 2 0 0 2 2 2 1 Dynamin family Zeta_toxin PF06414.12 RLN75118.1 - 0.0045 16.3 0.1 0.052 12.8 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin SMC_N PF02463.19 RLN75118.1 - 0.0057 16.1 0.8 2.5 7.5 0.2 3.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 RLN75118.1 - 0.012 15.8 2.5 0.053 13.6 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_25 PF13481.6 RLN75118.1 - 0.016 14.8 0.3 1.4 8.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 RLN75118.1 - 0.016 15.5 0.1 4.4 7.6 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RLN75118.1 - 0.017 14.7 0.1 0.9 9.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 RLN75118.1 - 0.057 13.6 0.0 0.75 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF3110 PF11360.8 RLN75118.1 - 0.094 12.9 0.1 0.51 10.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3110) AAA_18 PF13238.6 RLN75118.1 - 0.11 13.0 0.0 35 5.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 RLN75118.1 - 0.14 12.4 0.2 12 6.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 RLN75118.1 - 0.14 11.9 0.3 15 5.3 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF815 PF05673.13 RLN75118.1 - 0.22 10.7 1.9 2.4 7.2 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 RLN75118.1 - 0.44 10.2 1.4 8.2 6.1 0.1 2.7 3 0 0 3 3 3 0 AAA domain GCK PF07802.11 RLN75131.1 - 0.0027 18.1 0.8 0.0057 17.1 0.8 1.5 1 0 0 1 1 1 1 GCK domain CX9C PF16860.5 RLN75131.1 - 0.0081 16.2 0.7 0.014 15.4 0.7 1.4 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Peptidase_M14 PF00246.24 RLN75132.1 - 1e-17 64.9 0.7 2.9e-17 63.4 0.7 1.7 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 RLN75132.1 - 0.0058 15.7 0.1 0.54 9.3 0.0 2.3 2 0 0 2 2 2 2 Succinylglutamate desuccinylase / Aspartoacylase family BUD22 PF09073.10 RLN75132.1 - 0.59 9.4 24.7 1.1 8.6 24.7 1.3 1 0 0 1 1 1 0 BUD22 PapD-like PF14874.6 RLN75133.1 - 9.4e-08 32.2 0.1 1.9e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 Flagellar-associated PapD-like Adap_comp_sub PF00928.21 RLN75134.1 - 1.3e-20 73.9 0.0 2.1e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 RLN75134.1 - 0.0061 16.0 0.0 0.0095 15.4 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Serglycin PF04360.12 RLN75134.1 - 7.3 6.5 7.6 8.3 6.3 0.5 2.4 2 0 0 2 2 2 0 Serglycin CBF PF03914.17 RLN75136.1 - 1.4e-31 109.8 2.0 2e-31 109.3 0.5 2.0 2 0 0 2 2 2 1 CBF/Mak21 family DUF1455 PF07306.11 RLN75136.1 - 0.093 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) DUF4611 PF15387.6 RLN75136.1 - 0.96 9.7 4.6 1.6 9.0 3.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Rotamase PF00639.21 RLN75137.1 - 1.5e-11 45.1 0.0 3.2e-11 44.0 0.0 1.8 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 RLN75137.1 - 1.2e-10 41.9 0.0 5.8e-10 39.7 0.0 1.9 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 RLN75137.1 - 4.9e-05 24.1 0.0 8.8e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 RLN75137.1 - 0.00093 19.2 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 WW domain Glyco_hyd_101C PF17451.2 RLN75137.1 - 0.1 12.9 0.1 0.16 12.3 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain AA_permease_2 PF13520.6 RLN75138.1 - 3.7e-41 141.3 31.8 3.7e-41 141.3 31.8 1.8 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 RLN75138.1 - 1.8e-28 99.4 28.7 1.8e-28 99.4 28.7 1.9 1 1 1 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 RLN75138.1 - 1e-13 51.1 3.6 1.1e-12 47.8 3.6 3.0 1 0 0 1 1 1 1 C-terminus of AA_permease DUF4501 PF14946.6 RLN75138.1 - 2.5 8.1 4.7 6.6 6.8 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4501) ANAPC1 PF12859.7 RLN75145.1 - 3.3 8.3 8.9 9.1 6.9 8.9 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 1 MAGE_N PF12440.8 RLN75145.1 - 9.8 6.9 13.1 2.3 8.9 2.6 2.5 1 1 1 2 2 2 0 Melanoma associated antigen family N terminal DASH_Ask1 PF08655.10 RLN75146.1 - 1.1e-07 31.6 0.1 2.4e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 Citrate_bind PF16114.5 RLN75156.1 - 1.6e-89 298.1 0.0 2.8e-89 297.3 0.0 1.4 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 RLN75156.1 - 4.4e-24 85.2 0.1 3e-21 75.9 0.1 2.9 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 RLN75156.1 - 1.4e-14 54.2 0.1 3.3e-14 53.0 0.1 1.7 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 RLN75156.1 - 9.4e-07 29.4 0.0 3.3e-06 27.7 0.0 2.1 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 RLN75156.1 - 0.00085 18.9 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 RLN75156.1 - 0.034 13.9 0.9 0.071 12.9 0.0 2.1 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain CDT1 PF08839.11 RLN75157.1 - 6.4e-19 68.9 0.5 2e-18 67.3 0.0 2.0 2 0 0 2 2 2 1 DNA replication factor CDT1 like CDT1_C PF16679.5 RLN75157.1 - 1e-10 41.9 7.6 6.1e-10 39.4 1.0 3.3 2 1 1 3 3 3 2 DNA replication factor Cdt1 C-terminal domain DUF922 PF06037.11 RLN75157.1 - 0.015 15.1 0.1 0.28 10.9 0.0 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF922) SAM_1 PF00536.30 RLN75158.1 - 5.8e-06 26.6 0.0 1.3e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RLN75158.1 - 2.6e-05 24.2 0.0 5.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Phostensin_N PF13916.6 RLN75158.1 - 0.0028 18.0 1.2 0.032 14.6 0.2 2.5 2 0 0 2 2 2 1 PP1-regulatory protein, Phostensin N-terminal DUF2125 PF09898.9 RLN75159.1 - 0.0075 16.0 0.4 0.0089 15.7 0.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2125) EF-hand_1 PF00036.32 RLN75161.1 - 1.6e-21 74.2 12.9 2e-06 26.9 1.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RLN75161.1 - 1.4e-17 63.9 8.7 6.8e-09 36.1 1.4 4.1 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN75161.1 - 1.8e-15 55.5 10.4 0.0051 16.7 0.4 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RLN75161.1 - 8.4e-15 53.5 10.0 2e-05 23.8 0.6 4.1 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RLN75161.1 - 1.6e-11 43.9 11.1 3.6e-05 23.5 0.5 4.2 3 1 1 4 4 4 3 EF-hand domain pair SH3_4 PF06347.13 RLN75161.1 - 0.12 12.2 0.6 5.7 6.9 0.2 2.7 2 0 0 2 2 2 0 Bacterial SH3 domain EF-hand_4 PF12763.7 RLN75161.1 - 0.23 11.4 4.0 17 5.4 0.0 3.4 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand NUDIX PF00293.28 RLN75162.1 - 1.8e-14 53.9 0.0 2.7e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain zf-Di19 PF05605.12 RLN75162.1 - 4.9e-09 36.4 0.1 8.9e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding NUDIX_2 PF13869.6 RLN75162.1 - 0.01 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase zf-H2C2_2 PF13465.6 RLN75162.1 - 0.026 15.0 0.7 6.2 7.4 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger double domain Prok-RING_4 PF14447.6 RLN75162.1 - 0.034 14.0 0.4 9.5 6.2 0.1 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C2H2 PF00096.26 RLN75162.1 - 0.14 12.6 0.8 2.2 8.9 0.1 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN75162.1 - 0.52 11.3 2.8 16 6.7 0.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger WD40 PF00400.32 RLN75163.1 - 5e-13 49.3 24.8 0.00011 22.9 0.6 7.7 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN75163.1 - 3.1e-10 40.2 5.1 0.039 14.3 0.2 6.5 4 1 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 RLN75163.1 - 0.022 12.8 0.1 8 4.3 0.0 3.3 2 1 1 3 3 3 0 IKI3 family Vps16_N PF04841.13 RLN75163.1 - 0.055 12.2 0.0 0.31 9.7 0.0 2.1 2 0 0 2 2 2 0 Vps16, N-terminal region NAD_binding_9 PF13454.6 RLN75163.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Ras PF00071.22 RLN75164.1 - 7e-44 149.3 0.3 1.5e-43 148.2 0.3 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RLN75164.1 - 3.5e-25 88.6 0.1 1.2e-24 86.9 0.1 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN75164.1 - 1.9e-06 27.5 0.1 0.0006 19.3 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RLN75164.1 - 0.00013 21.9 0.0 0.32 10.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 RLN75164.1 - 0.0019 17.6 0.1 0.0086 15.4 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 RLN75164.1 - 0.008 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 RLN75164.1 - 0.01 15.9 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase LRR_8 PF13855.6 RLN75171.1 - 5.3e-16 58.1 17.3 8.2e-11 41.5 0.7 5.0 3 1 3 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 RLN75171.1 - 2.4e-08 34.2 18.1 2e-05 24.9 0.1 5.4 3 2 3 6 6 6 3 Leucine Rich repeats (2 copies) WW PF00397.26 RLN75171.1 - 4.7e-07 29.8 4.2 1.1e-06 28.6 4.2 1.6 1 0 0 1 1 1 1 WW domain LRR_6 PF13516.6 RLN75171.1 - 4.7e-07 29.3 15.9 0.0029 17.5 0.1 6.9 7 0 0 7 7 7 2 Leucine Rich repeat LRR_9 PF14580.6 RLN75171.1 - 0.00012 21.6 3.2 0.00029 20.4 3.2 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 RLN75171.1 - 0.00026 21.1 1.5 1.1e+02 3.9 0.0 6.0 5 0 0 5 5 5 0 Leucine Rich Repeat Acetyltransf_11 PF13720.6 RLN75171.1 - 0.12 12.8 0.1 6.9 7.2 0.0 2.8 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 WD40 PF00400.32 RLN75172.1 - 1e-14 54.7 5.2 0.00012 22.8 0.5 7.5 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN75172.1 - 5.7e-05 23.3 0.0 5.3 7.4 0.0 5.2 5 1 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain CALCOCO1 PF07888.11 RLN75172.1 - 0.00085 18.3 59.3 0.094 11.6 35.3 3.5 2 1 1 3 3 3 3 Calcium binding and coiled-coil domain (CALCOCO1) like zf-C2H2_6 PF13912.6 RLN75187.1 - 0.029 14.4 0.1 0.072 13.1 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger SDF PF00375.18 RLN75189.1 - 5.4e-77 259.4 34.9 1e-75 255.2 34.9 2.0 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family SipA PF09052.10 RLN75190.1 - 0.00088 18.9 0.3 0.00096 18.8 0.3 1.2 1 0 0 1 1 1 1 SipA N-terminal domain SNARE PF05739.19 RLN75190.1 - 0.15 12.1 0.2 0.51 10.4 0.0 1.9 2 0 0 2 2 2 0 SNARE domain CorA PF01544.18 RLN75190.1 - 0.16 11.3 1.8 0.19 11.0 1.8 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein zf-C2H2_6 PF13912.6 RLN75191.1 - 0.14 12.2 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger Herpes_pp85 PF04637.12 RLN75191.1 - 1.2 7.5 4.3 2.2 6.6 4.3 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) UreF PF01730.16 RLN75192.1 - 3.2e-25 89.3 9.1 3.2e-25 89.3 9.1 1.7 2 0 0 2 2 2 1 UreF Methyltransf_4 PF02390.17 RLN75195.1 - 1.2e-35 122.5 0.0 1.5e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 RLN75195.1 - 8.4e-06 25.7 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN75195.1 - 2.8e-05 24.8 0.0 6.2e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN75195.1 - 0.00068 20.3 0.0 0.0013 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PG_binding_3 PF09374.10 RLN75195.1 - 0.065 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Predicted Peptidoglycan domain Ubie_methyltran PF01209.18 RLN75195.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_33 PF10017.9 RLN75195.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Prenyltransf PF01255.19 RLN75196.1 - 1.7e-74 250.1 0.0 2e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Cid2 PF09774.9 RLN75196.1 - 0.021 15.3 0.0 0.03 14.7 0.0 1.2 1 0 0 1 1 1 0 Caffeine-induced death protein 2 PLDc_2 PF13091.6 RLN75196.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 PLD-like domain Myb_DNA-binding PF00249.31 RLN75197.1 - 1.6e-12 47.4 0.1 3.4e-11 43.2 0.0 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN75197.1 - 0.00013 22.2 0.0 0.00031 20.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-UBR PF02207.20 RLN75197.1 - 0.26 11.5 4.8 0.56 10.4 4.8 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) ComGG PF14173.6 RLN75197.1 - 0.37 11.2 2.4 1.2 9.5 0.2 2.5 3 0 0 3 3 3 0 ComG operon protein 7 zf-B_box PF00643.24 RLN75197.1 - 1.7 8.9 6.8 1.1 9.5 3.8 2.2 2 1 0 2 2 2 0 B-box zinc finger DZR PF12773.7 RLN75197.1 - 8.4 6.5 6.3 3.2 7.8 3.2 1.9 2 0 0 2 2 2 0 Double zinc ribbon IGPS PF00218.21 RLN75198.1 - 2.3e-49 167.9 0.1 1.4e-26 93.2 0.0 4.0 4 0 0 4 4 4 3 Indole-3-glycerol phosphate synthase PRAI PF00697.22 RLN75198.1 - 1.9e-40 138.7 0.2 4e-35 121.4 0.0 2.2 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase His_biosynth PF00977.21 RLN75198.1 - 0.039 13.4 2.2 6.3 6.2 0.1 3.5 4 1 1 5 5 5 0 Histidine biosynthesis protein DUF3605 PF12239.8 RLN75199.1 - 0.00021 21.6 1.5 0.00091 19.6 1.5 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF3605) 2OG-FeII_Oxy_3 PF13640.6 RLN75213.1 - 3.1e-14 53.6 0.0 8.9e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Lectin_leg-like PF03388.13 RLN75214.1 - 1.7e-36 125.7 0.7 2.6e-36 125.1 0.7 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 RLN75214.1 - 4e-10 40.0 1.5 9.5e-10 38.8 1.5 1.6 1 1 0 1 1 1 1 Bacterial lectin MIS13 PF08202.11 RLN75214.1 - 0.00025 20.5 2.4 0.00038 19.8 2.4 1.2 1 0 0 1 1 1 1 Mis12-Mtw1 protein family CemA PF03040.14 RLN75214.1 - 0.16 11.9 1.6 0.25 11.3 1.6 1.2 1 0 0 1 1 1 0 CemA family Stathmin PF00836.19 RLN75214.1 - 0.29 11.1 6.9 0.5 10.3 6.9 1.3 1 0 0 1 1 1 0 Stathmin family PX PF00787.24 RLN75223.1 - 2.6e-08 33.9 0.0 4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 PX domain PX PF00787.24 RLN75225.1 - 2.5e-10 40.3 0.2 4.3e-10 39.6 0.2 1.3 1 0 0 1 1 1 1 PX domain WH2 PF02205.20 RLN75225.1 - 5.1e-08 32.5 1.8 1.5e-07 31.0 1.8 1.8 1 0 0 1 1 1 1 WH2 motif Acyl_transf_3 PF01757.22 RLN75226.1 - 5.8e-13 48.6 29.1 8.4e-13 48.1 29.1 1.3 1 0 0 1 1 1 1 Acyltransferase family LNS2 PF08235.13 RLN75302.1 - 1.4e-62 211.1 0.0 2.3e-62 210.5 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 RLN75302.1 - 8.1e-15 54.6 1.6 5.4e-13 48.8 1.0 3.4 3 1 0 3 3 3 1 lipin, N-terminal conserved region IQ PF00612.27 RLN75302.1 - 3.8e-08 32.4 24.6 0.094 12.6 0.5 6.8 6 0 0 6 6 6 5 IQ calmodulin-binding motif Lipin_mid PF16876.5 RLN75302.1 - 4.6e-08 33.1 0.0 2e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 Lipin/Ned1/Smp2 multi-domain protein middle domain TPR_10 PF13374.6 RLN75302.1 - 6.7e-05 22.6 5.6 0.00058 19.6 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 RLN75302.1 - 0.0014 18.6 1.3 0.0088 16.1 0.7 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN75302.1 - 0.0043 17.3 1.1 0.022 15.1 0.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN75302.1 - 0.0064 16.6 2.6 0.048 13.9 0.8 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN75302.1 - 0.033 14.0 3.5 0.092 12.6 1.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat HTH_37 PF13744.6 RLN75302.1 - 0.11 12.4 0.0 0.39 10.7 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain FAT PF02259.23 RLN75303.1 - 0.0038 16.5 0.0 0.004 16.4 0.0 1.1 1 0 0 1 1 1 1 FAT domain LRR_6 PF13516.6 RLN75313.1 - 8.4e-16 56.6 32.8 0.074 13.1 0.0 8.6 9 0 0 9 9 9 7 Leucine Rich repeat LRR_1 PF00560.33 RLN75313.1 - 1.1e-08 34.5 15.9 1.1 10.1 0.1 8.6 8 0 0 8 8 8 4 Leucine Rich Repeat LRR_4 PF12799.7 RLN75313.1 - 2.5e-08 34.1 18.6 0.0042 17.5 0.9 5.3 3 1 1 5 5 5 3 Leucine Rich repeats (2 copies) DUF4476 PF14771.6 RLN75313.1 - 2e-05 24.8 0.9 0.0033 17.7 0.1 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4476) LRR_8 PF13855.6 RLN75313.1 - 0.1 12.3 21.0 10 5.9 2.5 5.9 1 1 4 5 5 5 0 Leucine rich repeat ADIP PF11559.8 RLN75326.1 - 0.018 15.2 2.2 0.04 14.0 2.2 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding NuDC PF16273.5 RLN75326.1 - 0.066 13.7 4.4 0.13 12.8 4.4 1.5 1 0 0 1 1 1 0 Nuclear distribution C domain bZIP_2 PF07716.15 RLN75326.1 - 1.6 8.9 5.0 4 7.6 5.0 1.7 1 0 0 1 1 1 0 Basic region leucine zipper DUF4618 PF15397.6 RLN75327.1 - 0.011 15.2 0.8 0.019 14.4 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Frankia_peptide PF14407.6 RLN75327.1 - 0.024 14.6 0.0 0.061 13.3 0.0 1.7 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. bZIP_2 PF07716.15 RLN75327.1 - 0.04 14.0 6.0 0.099 12.7 6.0 1.7 1 0 0 1 1 1 0 Basic region leucine zipper Med3 PF11593.8 RLN75327.1 - 0.3 10.2 4.8 0.42 9.7 4.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Uds1 PF15456.6 RLN75327.1 - 1.4 9.1 7.3 1.1 9.5 5.4 1.8 2 0 0 2 2 2 0 Up-regulated During Septation DUF2408 PF10303.9 RLN75331.1 - 0.0074 16.9 0.9 0.056 14.0 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2408) bZIP_1 PF00170.21 RLN75331.1 - 0.086 13.0 0.1 0.086 13.0 0.1 2.0 2 0 0 2 2 2 0 bZIP transcription factor MAD PF05557.13 RLN75332.1 - 0.036 12.5 4.4 0.059 11.7 4.4 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein TSC22 PF01166.18 RLN75332.1 - 0.044 14.1 1.8 1.8 8.9 0.2 2.7 1 1 1 2 2 2 0 TSC-22/dip/bun family GIT_CC PF16559.5 RLN75332.1 - 1.8 8.5 5.1 16 5.5 0.5 2.6 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_2 PF07716.15 RLN75332.1 - 9.9 6.3 12.7 6.8 6.9 3.8 3.1 3 0 0 3 3 3 0 Basic region leucine zipper DUF5076 PF16826.5 RLN75333.1 - 0.043 13.7 0.0 6.6 6.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5076) UPF0258 PF06789.12 RLN75333.1 - 0.079 13.1 0.0 9.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0258) ZapB PF06005.12 RLN75334.1 - 0.006 17.0 2.3 0.017 15.5 2.3 1.9 1 0 0 1 1 1 1 Cell division protein ZapB Birna_VP3 PF01767.16 RLN75334.1 - 0.016 15.3 0.3 0.025 14.7 0.3 1.3 1 0 0 1 1 1 0 Birnavirus VP3 protein CENP-Q PF13094.6 RLN75334.1 - 0.029 14.6 2.4 0.057 13.6 2.4 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Val_tRNA-synt_C PF10458.9 RLN75334.1 - 0.17 12.2 1.9 0.31 11.3 1.9 1.4 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Spc24 PF08286.11 RLN75334.1 - 0.19 12.0 4.4 0.13 12.6 1.9 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Vir_act_alpha_C PF10400.9 RLN75334.1 - 0.55 11.0 4.7 0.46 11.2 2.7 1.9 2 0 0 2 2 2 0 Virulence activator alpha C-term SPT6_acidic PF14632.6 RLN75335.1 - 0.2 12.2 5.4 0.93 10.1 3.1 2.4 2 0 0 2 2 2 0 Acidic N-terminal SPT6 DEAD PF00270.29 RLN75336.1 - 1.2e-40 139.1 0.0 1.7e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN75336.1 - 9.1e-17 61.4 0.0 6.4e-16 58.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN75336.1 - 2.1e-05 24.6 0.0 3.9e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RLN75336.1 - 0.0033 17.8 0.1 0.0067 16.8 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RLN75336.1 - 0.0046 16.7 0.0 0.0075 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RLN75336.1 - 0.0074 16.6 0.1 0.019 15.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 RLN75336.1 - 0.067 12.6 0.0 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein DUF2075 PF09848.9 RLN75336.1 - 0.078 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 RLN75336.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 1 0 1 1 1 0 Helicase DUF2508 PF10704.9 RLN75337.1 - 0.17 12.1 21.7 0.82 9.9 3.5 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) DUF3613 PF12266.8 RLN75337.1 - 0.93 9.3 4.3 4.4 7.1 4.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) BBL5 PF07289.11 RLN75338.1 - 1.7e-149 497.4 0.0 1.9e-149 497.3 0.0 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein PH_TFIIH PF08567.11 RLN75338.1 - 1.2e-05 25.5 0.0 0.043 14.1 0.0 2.4 2 0 0 2 2 2 2 TFIIH p62 subunit, N-terminal domain Voldacs PF03517.13 RLN75338.1 - 9.7e-05 22.5 0.1 0.32 11.1 0.0 2.4 2 0 0 2 2 2 2 Regulator of volume decrease after cellular swelling Vps36_ESCRT-II PF11605.8 RLN75338.1 - 0.00065 19.8 0.1 0.36 11.1 0.1 2.3 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.6 RLN75338.1 - 0.00085 19.6 0.0 0.011 16.0 0.0 2.3 2 0 0 2 2 2 1 Bacterial PH domain NAD_binding_1 PF00175.21 RLN75340.1 - 0.001 19.7 0.2 0.0023 18.6 0.2 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Ala_racemase_N PF01168.20 RLN75341.1 - 1.5e-25 90.1 3.2 1.5e-25 90.1 3.2 1.8 2 0 0 2 2 2 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 RLN75341.1 - 5.1e-21 75.1 0.2 1.9e-20 73.3 0.0 2.1 2 1 0 2 2 2 1 Putative serine dehydratase domain Ferritin_2 PF13668.6 RLN75341.1 - 0.028 14.6 0.6 0.051 13.8 0.6 1.4 1 0 0 1 1 1 0 Ferritin-like domain DUF2457 PF10446.9 RLN75342.1 - 0.13 11.4 4.5 0.045 12.9 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Med3 PF11593.8 RLN75342.1 - 0.15 11.3 1.9 0.21 10.8 1.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2508 PF10704.9 RLN75345.1 - 0.005 17.0 3.5 0.024 14.8 2.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2508) DUF2937 PF11157.8 RLN75345.1 - 0.025 14.3 0.4 0.045 13.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Presenilin PF01080.17 RLN75345.1 - 4.7 5.9 6.1 6.3 5.4 6.1 1.1 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 RLN75345.1 - 9.4 5.5 6.9 14 4.9 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NAD_binding_1 PF00175.21 RLN75346.1 - 4.1 8.1 5.6 1.4 9.6 0.6 2.6 2 1 1 3 3 3 0 Oxidoreductase NAD-binding domain Glyco_hydro_12 PF01670.16 RLN75347.1 - 0.12 12.4 0.2 0.48 10.4 0.1 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 12 14-3-3 PF00244.20 RLN75356.1 - 4.7e-97 323.8 1.6 5.4e-97 323.7 1.6 1.0 1 0 0 1 1 1 1 14-3-3 protein FYVE PF01363.21 RLN75370.1 - 1.3e-08 34.9 5.4 2.2e-08 34.1 5.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE PF01363.21 RLN75371.1 - 2.5e-12 46.7 11.6 7.9e-12 45.1 11.6 1.9 1 0 0 1 1 1 1 FYVE zinc finger FANCI_HD1 PF14679.6 RLN75371.1 - 0.18 11.7 2.2 0.44 10.5 0.0 2.7 3 0 0 3 3 3 0 FANCI helical domain 1 C1_2 PF03107.16 RLN75371.1 - 1.1 9.7 10.0 0.58 10.5 5.9 2.4 2 0 0 2 2 2 0 C1 domain zf-RING_5 PF14634.6 RLN75371.1 - 3.5 7.7 14.0 20 5.3 14.0 2.3 1 1 0 1 1 1 0 zinc-RING finger domain IBR PF01485.21 RLN75371.1 - 4 7.7 9.9 5.9 7.2 5.4 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 RLN75371.1 - 7.3 7.0 11.5 3.5 8.0 6.3 2.5 2 0 0 2 2 2 0 Ring finger domain Abhydrolase_6 PF12697.7 RLN75385.1 - 1.1e-15 58.9 17.7 4.3e-09 37.3 6.6 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN75385.1 - 6.9e-12 45.1 0.0 3.2e-05 23.3 0.0 2.7 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN75385.1 - 2e-06 27.6 0.0 0.0022 17.7 0.0 2.9 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN75386.1 - 1e-05 26.2 0.0 0.00026 21.7 0.0 2.0 1 1 0 2 2 2 1 Alpha/beta hydrolase family Sec20 PF03908.13 RLN75395.1 - 4e-07 29.9 0.4 7.1e-07 29.1 0.4 1.3 1 0 0 1 1 1 1 Sec20 V-SNARE_C PF12352.8 RLN75395.1 - 3.6e-05 24.0 1.9 7.1e-05 23.0 1.9 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus KxDL PF10241.9 RLN75395.1 - 0.0042 17.3 1.2 0.011 16.0 1.1 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein Peptidase_C25 PF01364.18 RLN75395.1 - 0.0099 15.1 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C25 SAM_1 PF00536.30 RLN75396.1 - 2.4e-08 34.3 0.1 4e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RLN75396.1 - 5.1e-08 32.9 0.0 8.1e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Cwf_Cwc_15 PF04889.12 RLN75396.1 - 0.012 15.3 9.1 0.011 15.5 9.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 RLN75396.1 - 7.4 5.8 15.1 8.5 5.6 15.1 1.1 1 0 0 1 1 1 0 NOA36 protein DEAD PF00270.29 RLN75413.1 - 1.6e-09 37.8 0.4 0.00033 20.5 0.0 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase CBS PF00571.28 RLN75413.1 - 0.049 14.1 0.0 0.13 12.7 0.0 1.7 2 0 0 2 2 2 0 CBS domain Helicase_C PF00271.31 RLN75413.1 - 0.1 13.0 0.0 0.34 11.3 0.0 1.9 1 1 0 1 1 1 0 Helicase conserved C-terminal domain MTP18 PF10558.9 RLN75488.1 - 8.1e-24 84.5 2.1 3e-22 79.4 2.1 2.0 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) His_Phos_1 PF00300.22 RLN75490.1 - 2.9e-19 69.5 0.6 1.2e-18 67.5 0.6 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.22 RLN75491.1 - 1.1e-13 51.3 0.2 2.8e-13 50.0 0.2 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Alk_phosphatase PF00245.20 RLN75492.1 - 1.4e-79 268.0 5.7 1.8e-79 267.7 5.7 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 RLN75492.1 - 0.00013 21.4 0.1 0.00034 20.0 0.0 1.6 1 1 0 1 1 1 1 Metalloenzyme superfamily His_Phos_1 PF00300.22 RLN75493.1 - 5.9e-11 42.4 0.1 1.1e-09 38.3 0.1 2.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SecY PF00344.20 RLN75495.1 - 1.3e-73 247.9 16.1 1.8e-73 247.5 16.1 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 RLN75495.1 - 1.3e-18 66.5 1.8 1.3e-18 66.5 0.1 2.0 2 0 0 2 2 2 1 Plug domain of Sec61p Pkinase PF00069.25 RLN75496.1 - 1.1e-26 93.7 0.0 9.9e-26 90.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN75496.1 - 6.6e-07 28.9 0.0 7.4e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN75497.1 - 1.1e-14 54.5 0.0 1.7e-14 53.8 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN75497.1 - 5.6e-05 22.6 0.0 7.6e-05 22.1 0.0 1.2 1 1 0 1 1 1 1 Protein tyrosine kinase P2_N PF18628.1 RLN75497.1 - 0.059 13.1 0.0 0.083 12.6 0.0 1.1 1 0 0 1 1 1 0 Viral coat protein P2 N-terminal domain DUF4570 PF15134.6 RLN75498.1 - 0.00086 19.3 4.0 0.00086 19.3 4.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4570) Exonuc_VII_L PF02601.15 RLN75498.1 - 1.2 8.6 5.8 1.5 8.3 5.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-H PF05837.12 RLN75498.1 - 3.9 7.9 13.1 0.31 11.5 5.5 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) LMBR1 PF04791.16 RLN75498.1 - 4.8 6.0 5.7 5.7 5.7 5.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein SMC_N PF02463.19 RLN75499.1 - 2.6e-57 193.8 44.1 3.4e-56 190.1 44.1 3.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 RLN75499.1 - 2.1e-20 73.2 0.2 7.8e-20 71.3 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 RLN75499.1 - 3.4e-13 50.1 3.4 9.3e-06 25.7 0.1 2.9 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RLN75499.1 - 7.9e-06 25.8 22.8 7.9e-06 25.8 22.8 4.3 2 2 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 RLN75499.1 - 0.00011 21.8 0.0 0.00028 20.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain LacI PF00356.21 RLN75499.1 - 0.00015 21.5 3.1 3.5 7.5 0.0 4.4 3 1 1 4 4 4 3 Bacterial regulatory proteins, lacI family AAA_23 PF13476.6 RLN75499.1 - 0.00054 20.5 105.0 2.7 8.5 53.8 6.6 3 2 0 3 3 3 1 AAA domain DUF4957 PF16318.5 RLN75500.1 - 1.3e-05 25.1 17.3 0.0052 16.7 1.0 7.1 5 1 2 7 7 7 5 Domain of unknown function (DUF4957) fn3 PF00041.21 RLN75501.1 - 6.8e-38 128.9 8.2 1.8e-09 37.8 0.1 6.2 6 0 0 6 6 6 6 Fibronectin type III domain Interfer-bind PF09294.10 RLN75501.1 - 0.018 15.3 0.0 49 4.3 0.0 4.4 6 0 0 6 6 6 0 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 RLN75501.1 - 0.049 14.0 0.4 12 6.4 0.0 3.8 5 0 0 5 5 5 0 Uncharacterised conserved protein (DUF2369) GYF_2 PF14237.6 RLN75502.1 - 0.0082 15.9 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 GYF domain 2 ANAPC16 PF17256.2 RLN75502.1 - 0.06 13.7 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 16 FdsD PF11390.8 RLN75502.1 - 0.16 12.3 0.6 2.5 8.5 0.0 3.2 4 0 0 4 4 4 0 NADH-dependant formate dehydrogenase delta subunit FdsD DUF1279 PF06916.13 RLN75503.1 - 0.0017 18.9 1.5 0.011 16.2 0.3 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1279) IRK_C PF17655.1 RLN75504.1 - 4.7e-13 49.1 0.0 6.6e-11 42.1 0.0 2.2 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain Paramyxo_P_V_N PF13825.6 RLN75504.1 - 0.016 14.7 0.5 0.029 13.8 0.5 1.3 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus La PF05383.17 RLN75505.1 - 2.6e-18 65.8 0.3 4.5e-18 65.0 0.3 1.4 1 0 0 1 1 1 1 La domain Peptidase_C15 PF01470.17 RLN75505.1 - 1.4e-13 51.5 0.0 4.4e-13 49.9 0.0 1.8 1 1 0 1 1 1 1 Pyroglutamyl peptidase RRM_1 PF00076.22 RLN75505.1 - 0.013 15.3 0.0 0.04 13.7 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF659 PF04937.15 RLN75506.1 - 6.3e-24 84.6 0.1 1.1e-23 83.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 RLN75506.1 - 1.5e-06 27.9 0.1 4.3e-05 23.2 0.1 2.7 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 RLN75506.1 - 1.8e-06 27.9 4.5 1.8e-06 27.9 4.5 1.8 2 0 0 2 2 2 1 BED zinc finger CnrY PF17524.2 RLN75506.1 - 0.12 12.6 0.6 10 6.4 0.3 2.8 2 0 0 2 2 2 0 Anti-sigma factor CnrY zf-RING_10 PF16685.5 RLN75506.1 - 0.13 12.4 3.9 0.13 12.4 2.4 1.7 2 0 0 2 2 2 0 zinc RING finger of MSL2 Methyltransf_3 PF01596.17 RLN75507.1 - 2.7e-49 167.2 0.0 3.6e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 RLN75507.1 - 2e-10 41.6 0.0 4.2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 RLN75507.1 - 3.2e-06 27.1 0.0 5.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 RLN75507.1 - 8.8e-06 26.3 0.1 4.4e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN75507.1 - 0.0021 17.8 0.0 0.0039 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN75507.1 - 0.0071 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 RLN75507.1 - 0.017 15.8 0.1 0.074 13.8 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 RLN75507.1 - 0.019 14.8 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 RLN75507.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 RLN75507.1 - 0.09 13.4 0.0 0.2 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 RLN75507.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family 2-Hacid_dh_C PF02826.19 RLN75519.1 - 6.3e-07 28.9 0.1 1.3e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4590 PF15257.6 RLN75519.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) HABP4_PAI-RBP1 PF04774.15 RLN75519.1 - 0.48 11.3 12.1 0.17 12.8 6.9 2.6 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family DNA_pol_phi PF04931.13 RLN75519.1 - 2.8 5.9 5.7 4.4 5.3 5.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi Prenyltrans PF00432.21 RLN75520.1 - 5.1e-32 109.3 16.3 2.2e-11 43.3 0.2 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat 2-Hacid_dh_C PF02826.19 RLN75521.1 - 9.9e-44 148.8 0.0 1.6e-43 148.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Arm PF00514.23 RLN75521.1 - 2.9e-39 131.9 17.4 2.5e-06 27.3 0.1 11.3 11 1 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN75521.1 - 1.9e-09 37.8 19.4 0.0017 18.8 0.0 7.4 5 1 2 7 7 7 4 HEAT-like repeat HEAT PF02985.22 RLN75521.1 - 3.5e-07 29.9 8.7 2.8 8.4 0.0 9.8 10 0 0 10 10 10 1 HEAT repeat Atx10homo_assoc PF09759.9 RLN75521.1 - 2e-06 27.7 5.9 2.5 8.2 0.0 6.5 3 2 4 7 7 7 2 Spinocerebellar ataxia type 10 protein domain NAD_binding_2 PF03446.15 RLN75521.1 - 2.6e-05 24.4 0.0 6.9e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Arm_2 PF04826.13 RLN75521.1 - 0.00049 19.6 0.1 2.2 7.7 0.0 3.9 1 1 1 3 3 3 1 Armadillo-like HEAT_2 PF13646.6 RLN75521.1 - 0.0014 19.0 28.4 0.11 12.9 1.1 6.3 1 1 7 8 8 8 3 HEAT repeats DUF1654 PF07867.11 RLN75521.1 - 0.0046 16.7 0.1 2.4 8.0 0.0 3.9 2 1 2 4 4 4 1 Protein of unknown function (DUF1654) F420_oxidored PF03807.17 RLN75521.1 - 0.036 14.6 0.0 0.21 12.2 0.0 2.4 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N_2 PF13602.6 RLN75521.1 - 0.053 14.6 0.0 0.2 12.7 0.0 2.1 1 0 0 1 1 1 0 Zinc-binding dehydrogenase HEAT_PBS PF03130.16 RLN75521.1 - 0.17 12.6 38.4 5.8 7.9 0.1 10.7 12 0 0 12 12 10 0 PBS lyase HEAT-like repeat Aconitase_B_N PF11791.8 RLN75521.1 - 0.29 11.2 2.9 11 6.1 0.1 4.1 3 2 2 5 5 5 0 Aconitate B N-terminal domain Abhydrolase_8 PF06259.12 RLN75521.1 - 1.4 8.5 16.4 0.82 9.3 1.2 4.2 1 1 4 5 5 5 0 Alpha/beta hydrolase Peptidase_M1 PF01433.20 RLN75528.1 - 2.2e-48 164.7 0.0 2.2e-48 164.7 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 RLN75528.1 - 9.9e-26 90.1 0.0 2.1e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 RLN75528.1 - 7.4e-18 65.4 0.0 7.4e-18 65.4 0.0 2.6 2 1 0 2 2 2 1 Peptidase M1 N-terminal domain MIF4G PF02854.19 RLN75528.1 - 1.6e-11 44.3 0.2 2.5e-11 43.6 0.2 1.3 1 0 0 1 1 1 1 MIF4G domain PAM2 PF07145.15 RLN75528.1 - 0.047 13.4 4.1 2.3 8.1 0.3 2.7 2 0 0 2 2 2 0 Ataxin-2 C-terminal region TFIIA PF03153.13 RLN75528.1 - 1.3 9.0 23.2 2.2 8.2 23.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDK5_activator PF03261.15 RLN75528.1 - 5.1 6.5 12.0 8.7 5.8 12.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein SDA1 PF05285.12 RLN75528.1 - 7.7 5.8 18.4 14 4.9 18.4 1.3 1 0 0 1 1 1 0 SDA1 FoP_duplication PF13865.6 RLN75528.1 - 8 7.1 14.3 22 5.7 14.3 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Hydrolase_4 PF12146.8 RLN75529.1 - 6.7e-52 176.1 0.0 8e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN75529.1 - 6.7e-12 46.5 0.3 9.6e-12 46.0 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN75529.1 - 1.1e-08 35.0 0.1 3.8e-07 30.0 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 RLN75529.1 - 0.00085 19.0 0.0 0.00094 18.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 RLN75529.1 - 0.0023 17.4 0.1 0.2 11.1 0.0 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 RLN75529.1 - 0.0097 15.7 0.1 6.4 6.5 0.0 3.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DLH PF01738.18 RLN75529.1 - 0.016 14.8 0.0 1 8.9 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Aldedh PF00171.22 RLN75543.1 - 1.4e-40 139.2 0.2 1.7e-40 138.9 0.2 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Baculo_VP91_N PF08475.10 RLN75543.1 - 6.9 6.3 5.7 13 5.4 5.7 1.5 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal zf-RING_UBOX PF13445.6 RLN75554.1 - 0.00084 19.3 1.8 0.00084 19.3 1.8 2.1 1 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 RLN75554.1 - 0.0016 18.8 8.1 0.0027 18.0 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 RLN75554.1 - 0.0017 18.0 2.2 0.0041 16.8 2.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 RLN75554.1 - 0.0054 16.6 3.0 0.0082 16.0 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN75554.1 - 0.01 16.1 5.4 0.023 15.0 5.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 RLN75554.1 - 0.012 15.4 8.4 0.022 14.6 8.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN75554.1 - 0.027 14.3 3.3 0.069 13.0 3.4 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2574 PF10836.8 RLN75554.1 - 0.047 13.6 0.0 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2574) Prok-RING_4 PF14447.6 RLN75554.1 - 0.25 11.3 6.6 0.47 10.4 6.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 RLN75554.1 - 0.32 10.7 3.8 0.58 9.8 3.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 RLN75554.1 - 0.44 10.5 2.1 1.1 9.2 2.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein PHD PF00628.29 RLN75554.1 - 2.1 8.3 5.3 4.6 7.2 5.3 1.6 1 0 0 1 1 1 0 PHD-finger Zn-ribbon_8 PF09723.10 RLN75554.1 - 2.1 8.5 5.5 0.61 10.2 0.6 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_5 PF14634.6 RLN75554.1 - 3 7.9 7.5 9.9 6.2 7.5 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3H2C3 PF17122.5 RLN75554.1 - 3.8 7.6 8.1 7.1 6.8 8.1 1.5 1 0 0 1 1 1 0 Zinc-finger TPR_2 PF07719.17 RLN75555.1 - 0.0027 17.7 9.0 0.45 10.8 0.6 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN75555.1 - 0.0028 18.1 5.4 1 9.9 0.3 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN75555.1 - 0.0045 17.7 15.4 0.033 15.0 0.8 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN75555.1 - 0.0046 17.1 3.8 1.8 9.0 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN75555.1 - 0.024 14.9 5.7 0.19 12.0 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN75555.1 - 0.093 12.6 0.7 0.093 12.6 0.7 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN75555.1 - 0.17 12.1 3.9 1.5 9.1 0.2 3.5 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 RLN75555.1 - 3.5 8.5 15.0 0.16 12.6 2.6 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN75555.1 - 5.2 7.8 21.2 3.2 8.5 2.6 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat ABC_tran PF00005.27 RLN75566.1 - 2.1e-08 34.8 0.4 1.2e-07 32.3 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 RLN75566.1 - 0.027 14.3 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system UBX PF00789.20 RLN75567.1 - 1.7e-15 57.0 0.0 3.3e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 RLN75567.1 - 1.3e-08 34.9 0.0 2.9e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UIM PF02809.20 RLN75567.1 - 9.7e-05 22.0 0.5 0.00029 20.5 0.5 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif ROK PF00480.20 RLN75568.1 - 6.9e-52 176.8 0.0 9.4e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.16 RLN75568.1 - 0.00017 20.7 0.8 0.066 12.2 0.7 2.9 3 0 0 3 3 3 2 Glucokinase Sec1 PF00995.23 RLN75569.1 - 3.5e-94 317.1 0.0 4.3e-94 316.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family TACC_C PF05010.14 RLN75569.1 - 0.00067 19.5 0.1 0.0012 18.7 0.1 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Sigma70_r4 PF04545.16 RLN75569.1 - 0.015 14.8 0.0 0.041 13.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 RLN75569.1 - 0.091 12.4 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Methyltransf_28 PF02636.17 RLN75570.1 - 7.7e-33 114.2 0.0 1.1e-32 113.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 RLN75570.1 - 2.9e-05 24.7 0.0 6.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN75570.1 - 0.00028 21.5 0.0 0.00065 20.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 RLN75570.1 - 0.00046 19.3 0.0 0.00083 18.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 RLN75570.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_33 PF10017.9 RLN75570.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent FHA PF00498.26 RLN75579.1 - 0.0008 19.7 0.0 0.016 15.6 0.0 2.6 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 RLN75579.1 - 0.0011 19.3 0.0 0.0028 17.9 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain eIF3_subunit PF08597.10 RLN75579.1 - 0.85 9.5 10.8 0.21 11.4 7.4 1.5 1 1 0 2 2 2 0 Translation initiation factor eIF3 subunit CENP-X PF09415.10 RLN75580.1 - 9.4e-16 57.9 1.9 6.1e-15 55.3 0.1 2.2 1 1 1 2 2 2 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.23 RLN75580.1 - 0.085 13.2 0.5 0.19 12.0 0.1 1.8 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PQ-loop PF04193.14 RLN75601.1 - 5.5e-09 35.7 0.4 6.9e-09 35.4 0.4 1.2 1 0 0 1 1 1 1 PQ loop repeat Dioxygenase_C PF00775.21 RLN75602.1 - 0.00046 19.7 0.0 0.00076 19.0 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Aa_trans PF01490.18 RLN75603.1 - 7.6e-31 107.2 26.2 2.6e-20 72.5 4.3 3.0 3 0 0 3 3 3 3 Transmembrane amino acid transporter protein MT PF12777.7 RLN75627.1 - 2.6e-53 181.3 5.0 3.4e-53 180.9 5.0 1.1 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 RLN75627.1 - 6.7e-09 35.2 0.4 6.7e-09 35.2 0.4 2.2 2 0 0 2 2 2 1 ATP-binding dynein motor region Spc7 PF08317.11 RLN75627.1 - 0.00094 18.1 6.9 0.00094 18.1 6.9 2.2 2 0 0 2 2 2 1 Spc7 kinetochore protein Viral_DNA_Zn_bi PF03728.13 RLN75627.1 - 0.029 14.9 0.2 0.099 13.2 0.1 2.0 1 1 0 1 1 1 0 Viral DNA-binding protein, zinc binding domain DUF4201 PF13870.6 RLN75627.1 - 0.054 13.2 0.2 0.054 13.2 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) ATG16 PF08614.11 RLN75627.1 - 0.22 11.7 13.8 0.49 10.6 0.2 2.9 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 RLN75627.1 - 0.73 10.3 7.0 11 6.4 0.0 2.4 2 0 0 2 2 2 0 Fez1 BRE1 PF08647.11 RLN75627.1 - 6.1 7.0 12.6 0.83 9.8 0.2 3.2 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase EF-hand_7 PF13499.6 RLN75652.1 - 5.5e-08 33.2 0.0 1.5e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN75652.1 - 1.7e-05 24.0 0.0 5.4e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RLN75652.1 - 4.9e-05 22.9 0.0 0.00015 21.4 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 RLN75652.1 - 0.00088 18.7 0.0 0.0021 17.5 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 RLN75652.1 - 0.033 14.0 0.0 0.39 10.6 0.0 2.2 1 1 1 2 2 2 0 EF-hand domain pair Peptidase_C53 PF05550.11 RLN75652.1 - 0.037 13.7 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Pestivirus Npro endopeptidase C53 F-box_4 PF15966.5 RLN75701.1 - 0.087 12.7 0.4 6.6 6.7 0.1 2.6 3 0 0 3 3 3 0 F-box LBR_tudor PF09465.10 RLN75702.1 - 0.0033 17.2 2.0 0.01 15.6 0.1 2.5 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain Kinesin PF00225.23 RLN75703.1 - 1.3e-99 333.3 0.0 2e-99 332.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN75703.1 - 2e-16 60.3 0.1 9.9e-16 58.0 0.1 2.1 1 1 0 1 1 1 1 Microtubule binding Trimer_CC PF08954.11 RLN75703.1 - 0.013 15.0 5.7 0.039 13.5 5.7 1.8 1 0 0 1 1 1 0 Trimerisation motif Bac_DnaA PF00308.18 RLN75703.1 - 0.087 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein DUF3450 PF11932.8 RLN75703.1 - 0.088 12.1 7.9 0.016 14.5 3.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ADIP PF11559.8 RLN75703.1 - 0.17 12.0 9.2 1.2 9.2 6.5 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding BBP1_C PF15272.6 RLN75703.1 - 0.92 9.3 9.8 0.15 11.9 4.5 2.0 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal CCDC-167 PF15188.6 RLN75703.1 - 7.8 6.9 7.5 2 8.8 1.3 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 zf-C2H2_10 PF16588.5 RLN75704.1 - 9.1 6.1 7.0 3.6 7.4 0.4 2.8 3 0 0 3 3 3 0 C2H2 zinc-finger ADK PF00406.22 RLN75705.1 - 4.6e-27 95.0 0.2 1.3e-12 48.0 0.0 2.2 1 1 1 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 RLN75705.1 - 1.4e-13 51.4 0.1 1.1e-11 45.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RLN75705.1 - 0.016 15.7 0.0 0.022 15.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RLN75705.1 - 0.044 14.0 0.0 0.048 13.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RLN75705.1 - 0.053 13.8 0.0 0.1 12.8 0.0 1.6 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 RLN75705.1 - 0.1 12.0 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI HSP70 PF00012.20 RLN75706.1 - 3e-63 214.0 0.0 4.9e-63 213.3 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN75706.1 - 0.0064 15.4 1.6 0.033 13.0 0.8 2.1 2 0 0 2 2 2 1 MreB/Mbl protein BUD22 PF09073.10 RLN75707.1 - 0.0065 15.9 25.2 0.0074 15.7 25.2 1.1 1 0 0 1 1 1 1 BUD22 GREB1 PF15782.5 RLN75707.1 - 8.5 3.3 8.7 11 3.0 8.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ABC_membrane PF00664.23 RLN75709.1 - 3.3e-101 338.5 32.5 2.2e-54 185.0 3.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN75709.1 - 3.1e-69 231.8 0.0 4.3e-34 118.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN75709.1 - 2.9e-11 43.3 0.2 0.0048 16.4 0.0 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RLN75709.1 - 6.5e-08 32.2 0.8 0.0068 16.1 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 RLN75709.1 - 3.9e-07 29.5 0.0 0.036 13.4 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.6 RLN75709.1 - 4e-06 27.3 7.2 0.0056 17.1 0.4 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 RLN75709.1 - 4.8e-06 26.4 2.0 0.12 12.1 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RLN75709.1 - 5.3e-06 26.8 4.2 0.057 13.7 0.1 3.7 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.6 RLN75709.1 - 6.1e-06 25.9 0.4 0.21 11.1 0.0 3.6 4 0 0 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 RLN75709.1 - 6.1e-06 26.2 0.1 0.087 12.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 RLN75709.1 - 1.3e-05 24.2 3.0 0.018 13.8 0.1 2.7 3 0 0 3 3 2 2 Predicted ATPase of the ABC class APS_kinase PF01583.20 RLN75709.1 - 1.8e-05 24.7 0.1 0.17 11.7 0.0 2.4 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_5 PF07728.14 RLN75709.1 - 4.3e-05 23.5 0.5 0.56 10.2 0.0 4.2 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 RLN75709.1 - 5.5e-05 23.1 3.7 0.77 9.5 0.0 4.1 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RLN75709.1 - 9.9e-05 22.2 0.0 0.19 11.4 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 RLN75709.1 - 0.00032 20.9 1.3 0.18 11.8 0.2 2.8 2 1 0 2 2 2 1 Helicase HerA, central domain AAA_18 PF13238.6 RLN75709.1 - 0.00041 20.9 0.0 0.72 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 RLN75709.1 - 0.00045 20.4 0.0 1.3 9.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 RLN75709.1 - 0.00082 19.7 0.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 RLN75709.1 - 0.00082 19.8 4.2 0.18 12.3 0.2 4.0 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 RLN75709.1 - 0.00092 18.8 0.1 0.83 9.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region G-alpha PF00503.20 RLN75709.1 - 0.0013 18.0 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_24 PF13479.6 RLN75709.1 - 0.0014 18.4 0.1 1.2 8.8 0.0 2.7 3 0 0 3 3 2 1 AAA domain SRP54 PF00448.22 RLN75709.1 - 0.0029 17.3 0.0 0.53 9.9 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 RLN75709.1 - 0.0048 16.6 1.6 3.4 7.4 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein SbcCD_C PF13558.6 RLN75709.1 - 0.013 15.7 6.1 3.1 8.1 0.5 3.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 RLN75709.1 - 0.018 15.1 0.2 9.2 6.4 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Mg_chelatase PF01078.21 RLN75709.1 - 0.018 14.4 0.0 0.35 10.2 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 RLN75709.1 - 0.026 15.0 0.5 3.2 8.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 RLN75709.1 - 0.038 14.4 0.7 27 5.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 RLN75709.1 - 0.045 13.5 5.0 11 5.7 0.6 3.9 2 2 0 2 2 2 0 DEAD/DEAH box helicase Rad17 PF03215.15 RLN75709.1 - 0.07 13.1 0.6 14 5.5 0.0 3.5 4 0 0 4 4 3 0 Rad17 P-loop domain ATP-synt_ab PF00006.25 RLN75709.1 - 0.088 12.5 0.0 7.8 6.1 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Ploopntkinase3 PF18751.1 RLN75709.1 - 0.092 12.6 0.1 15 5.5 0.0 2.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ATP_bind_1 PF03029.17 RLN75709.1 - 0.095 12.5 0.1 5.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 RLN75709.1 - 0.097 12.6 0.4 35 4.3 0.0 3.8 4 0 0 4 4 4 0 NTPase DUF3621 PF12285.8 RLN75709.1 - 0.11 12.8 0.1 0.23 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3621) NACHT PF05729.12 RLN75709.1 - 0.28 11.1 3.0 15 5.5 0.0 3.0 4 0 0 4 4 3 0 NACHT domain G8 PF10162.9 RLN75710.1 - 3.1e-09 37.0 0.0 7e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 G8 domain Beta_helix PF13229.6 RLN75710.1 - 2.7e-07 30.6 0.4 1.7e-05 24.7 0.1 3.1 2 1 1 3 3 3 1 Right handed beta helix region NosD PF05048.13 RLN75710.1 - 0.00062 19.1 0.1 0.0066 15.7 0.3 2.2 1 1 1 2 2 2 1 Periplasmic copper-binding protein (NosD) BclA_C PF18573.1 RLN75710.1 - 0.13 12.1 0.2 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 BclA C-terminal domain p450 PF00067.22 RLN75711.1 - 6.9e-70 236.1 0.1 8.6e-70 235.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.6 RLN75712.1 - 3.9e-35 121.5 48.6 5.3e-35 121.1 48.6 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN75712.1 - 1.3e-21 76.8 48.6 5.3e-21 74.8 48.6 1.9 1 1 0 1 1 1 1 Amino acid permease CD34_antigen PF06365.12 RLN75712.1 - 0.081 12.5 0.0 0.25 10.9 0.0 1.8 1 0 0 1 1 1 0 CD34/Podocalyxin family Phage_holin_3_6 PF07332.11 RLN75712.1 - 0.13 12.3 0.1 0.13 12.3 0.1 5.4 3 2 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III p450 PF00067.22 RLN75713.1 - 1.7e-73 247.9 0.0 2.2e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 RLN75714.1 - 3.8e-145 484.2 0.0 1.7e-77 261.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DIE2_ALG10 PF04922.12 RLN75715.1 - 1.9e-26 93.3 0.1 2.2e-26 93.1 0.1 1.0 1 0 0 1 1 1 1 DIE2/ALG10 family p450 PF00067.22 RLN75716.1 - 6.8e-64 216.3 0.0 8.8e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.12 RLN75717.1 - 9.3e-17 60.9 7.3 9.3e-17 60.9 7.3 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN75717.1 - 8.7e-16 58.1 0.0 1.5e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN75717.1 - 0.0007 19.0 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN75717.1 - 0.014 14.7 0.1 0.023 14.0 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 RLN75717.1 - 0.03 15.4 0.0 0.043 14.9 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Cu_amine_oxid PF01179.20 RLN75718.1 - 1.2e-150 502.0 0.0 1.5e-150 501.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 RLN75718.1 - 1.4e-15 57.5 0.0 7.8e-15 55.1 0.0 2.2 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 RLN75718.1 - 2e-09 37.5 0.0 5.2e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain FYVE PF01363.21 RLN75736.1 - 1.9e-11 43.9 7.0 3.9e-11 42.9 7.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN75736.1 - 0.0016 18.7 4.7 0.0068 16.6 4.7 2.1 1 0 0 1 1 1 1 FYVE-type zinc finger START PF01852.19 RLN75736.1 - 0.0026 17.2 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 START domain HypA PF01155.19 RLN75736.1 - 0.068 13.2 2.9 0.062 13.3 1.0 1.9 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RRF PF01765.19 RLN75736.1 - 0.15 12.0 0.2 0.32 10.9 0.2 1.5 1 0 0 1 1 1 0 Ribosome recycling factor C1_1 PF00130.22 RLN75736.1 - 0.2 11.6 5.7 0.042 13.7 2.0 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_L40e PF01020.17 RLN75736.1 - 0.39 10.6 4.0 0.98 9.4 4.0 1.6 1 0 0 1 1 1 0 Ribosomal L40e family zinc_ribbon_4 PF13717.6 RLN75736.1 - 1.9 8.5 8.4 9 6.3 0.5 3.4 2 1 1 3 3 3 0 zinc-ribbon domain zf-B_box PF00643.24 RLN75736.1 - 8.3 6.7 6.0 28 4.9 6.0 1.9 1 1 0 1 1 1 0 B-box zinc finger Dimer_Tnp_hAT PF05699.14 RLN75737.1 - 0.002 17.9 0.0 0.0049 16.6 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase PF00069.25 RLN75738.1 - 1.5e-45 155.6 0.0 2.3e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN75738.1 - 4e-40 137.7 0.0 5e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RLN75738.1 - 0.022 13.7 0.1 0.12 11.3 0.1 1.9 1 1 0 1 1 1 0 Haspin like kinase domain VPS13_C PF16909.5 RLN75739.1 - 7.6e-56 188.7 6.5 1.7e-53 181.0 0.6 2.4 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 RLN75739.1 - 6.4e-33 114.5 0.0 2.6e-31 109.2 0.0 3.2 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 RLN75739.1 - 3.5e-28 98.1 0.1 1e-27 96.5 0.1 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 RLN75739.1 - 4.6e-14 52.5 0.0 4.8e-11 42.5 0.0 2.7 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 Apt1 PF10351.9 RLN75739.1 - 0.00062 18.8 0.0 0.0019 17.2 0.0 1.8 2 0 0 2 2 2 1 Golgi-body localisation protein domain ATG_C PF09333.11 RLN75739.1 - 0.0024 18.2 0.9 0.008 16.5 0.9 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain CAP PF00188.26 RLN75763.1 - 4.6e-25 88.9 5.1 7.7e-25 88.2 5.1 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SNF2_N PF00176.23 RLN75764.1 - 2.9e-71 240.0 0.5 6.4e-71 238.9 0.5 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 RLN75764.1 - 8.2e-37 125.7 0.1 8.2e-37 125.7 0.1 3.5 4 0 0 4 4 3 1 SLIDE Helicase_C PF00271.31 RLN75764.1 - 8.6e-20 71.2 0.1 8.2e-19 68.0 0.0 2.8 3 0 0 3 3 2 1 Helicase conserved C-terminal domain HMG_box PF00505.19 RLN75764.1 - 5.6e-18 65.1 15.8 6.2e-12 45.8 0.1 4.4 3 1 0 3 3 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 RLN75764.1 - 8.7e-18 64.7 7.1 1.9e-10 41.2 0.3 4.7 4 0 0 4 4 2 2 HMG-box domain ResIII PF04851.15 RLN75764.1 - 9.8e-10 38.7 1.1 1.3e-08 35.0 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 RLN75764.1 - 2e-06 27.2 0.2 2e-06 27.2 0.2 2.6 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 RLN75764.1 - 4.9e-06 26.4 2.8 6.8e-06 26.0 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 RLN75764.1 - 2.7e-05 24.3 0.1 0.00062 19.9 0.0 3.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain Ras_bdg_2 PF14847.6 RLN75764.1 - 0.0044 17.3 0.8 1.5 9.2 0.0 3.0 2 0 0 2 2 2 1 Ras-binding domain of Byr2 Myb_DNA-bind_6 PF13921.6 RLN75764.1 - 0.027 14.7 0.0 0.19 12.0 0.0 2.6 2 0 0 2 2 1 0 Myb-like DNA-binding domain DAPG_hydrolase PF18089.1 RLN75764.1 - 0.17 11.4 1.1 0.38 10.3 1.1 1.6 1 0 0 1 1 1 0 DAPG hydrolase PhiG domain AAA_22 PF13401.6 RLN75764.1 - 0.75 10.1 0.0 0.75 10.1 0.0 3.8 4 0 0 4 4 4 0 AAA domain PIN_9 PF18477.1 RLN75766.1 - 0.11 12.8 0.0 0.14 12.5 0.0 1.1 1 0 0 1 1 1 0 PIN like domain FYVE_2 PF02318.16 RLN75767.1 - 0.016 15.4 5.5 0.016 15.4 5.5 1.5 1 1 0 1 1 1 0 FYVE-type zinc finger CHCH PF06747.13 RLN75767.1 - 0.043 14.0 2.1 0.11 12.7 2.0 1.8 1 1 0 1 1 1 0 CHCH domain Pox_G5 PF04599.12 RLN75767.1 - 0.19 10.7 3.7 0.21 10.5 3.7 1.0 1 0 0 1 1 1 0 Poxvirus G5 protein Bud13 PF09736.9 RLN75767.1 - 1.1 9.6 8.9 0.65 10.4 5.6 1.8 1 1 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex CMAS PF02353.20 RLN75768.1 - 1.3e-87 293.6 0.1 1.6e-87 293.3 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 RLN75768.1 - 1.6e-14 54.4 0.0 3.4e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN75768.1 - 4.1e-12 46.6 0.0 9.1e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN75768.1 - 1.2e-11 44.6 0.0 1.7e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN75768.1 - 4.2e-10 39.7 0.0 6.7e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN75768.1 - 3.2e-09 37.4 0.0 8.5e-09 36.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 RLN75768.1 - 3.3e-05 23.5 0.0 5.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 RLN75768.1 - 0.0004 19.9 0.0 0.00064 19.2 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 RLN75768.1 - 0.00086 19.3 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 RLN75768.1 - 0.0016 18.2 0.0 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 RLN75768.1 - 0.006 16.2 0.0 0.0097 15.5 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 RLN75768.1 - 0.0083 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GCD14 PF08704.10 RLN75768.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_15 PF09445.10 RLN75768.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase ADH_zinc_N PF00107.26 RLN75768.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Ald_Xan_dh_C2 PF02738.18 RLN75769.1 - 2.7e-186 620.3 1.0 3.9e-186 619.8 1.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 RLN75769.1 - 1.6e-42 145.1 0.0 5.1e-42 143.5 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 RLN75769.1 - 4.3e-29 101.1 0.0 1.4e-28 99.4 0.0 2.0 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 RLN75769.1 - 2.2e-27 94.9 0.3 6.2e-27 93.4 0.3 1.9 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 RLN75769.1 - 9e-27 93.3 0.4 2.7e-26 91.7 0.0 2.1 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 RLN75769.1 - 6e-08 32.5 1.1 6e-08 32.5 1.1 2.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.17 RLN75769.1 - 0.083 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 DUF218 domain DHODB_Fe-S_bind PF10418.9 RLN75769.1 - 1.9 8.4 6.9 0.36 10.7 2.3 2.2 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B PSI_integrin PF17205.3 RLN75770.1 - 1.2 8.9 11.5 3.5 7.4 11.5 1.9 1 1 0 1 1 1 0 Integrin plexin domain PSI PF01437.25 RLN75770.1 - 1.3 9.6 14.8 5.9 7.5 14.8 2.1 1 1 0 1 1 1 0 Plexin repeat DUF1974 PF09317.11 RLN75771.1 - 2.8e-57 194.5 0.0 5.4e-57 193.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1974) Acyl-CoA_dh_N PF02771.16 RLN75771.1 - 3.2e-18 66.4 0.0 8.1e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 RLN75771.1 - 3.1e-09 37.2 0.1 5.5e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RLN75771.1 - 6.2e-08 32.7 0.0 1.5e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HEAT PF02985.22 RLN75772.1 - 0.013 15.7 0.1 1.5 9.3 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat HEAT_2 PF13646.6 RLN75772.1 - 0.052 13.9 0.0 0.29 11.5 0.0 1.9 1 1 0 1 1 1 0 HEAT repeats PaaX_C PF08223.11 RLN75780.1 - 0.65 10.3 3.0 2.7 8.3 0.4 2.9 2 2 0 2 2 2 0 PaaX-like protein C-terminal domain MIP PF00230.20 RLN75792.1 - 8.6e-12 45.3 1.0 1.2e-11 44.8 1.0 1.2 1 1 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 RLN75793.1 - 0.00028 20.7 0.1 0.00035 20.4 0.1 1.2 1 0 0 1 1 1 1 Major intrinsic protein MMR_HSR1 PF01926.23 RLN75907.1 - 1.2e-08 35.1 0.1 6.9e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN75907.1 - 0.00024 20.6 0.1 0.0061 16.1 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 RLN75907.1 - 0.1 12.6 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Dynamin family CLP1_P PF16575.5 RLN75908.1 - 1.5e-54 184.7 0.0 5e-54 183.0 0.0 1.9 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 RLN75908.1 - 3e-30 104.3 0.0 5.2e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 RLN75908.1 - 1.7e-09 38.1 0.0 2.6e-06 27.8 0.1 2.4 1 1 1 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 RLN75908.1 - 0.086 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RuvB_N PF05496.12 RLN75908.1 - 0.098 12.4 0.0 0.6 9.9 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain GTP_EFTU PF00009.27 RLN75908.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 RLN75908.1 - 0.15 12.6 0.0 0.42 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain Snurportin1 PF11538.8 RLN75909.1 - 0.007 16.5 2.2 0.007 16.5 2.2 2.0 2 0 0 2 2 2 1 Snurportin1 PPR_2 PF13041.6 RLN75910.1 - 1.9e-36 124.0 0.5 9.5e-12 44.9 0.0 8.4 6 2 3 9 9 9 5 PPR repeat family PPR_3 PF13812.6 RLN75910.1 - 3.7e-30 103.8 0.0 7.8e-07 29.1 0.0 7.0 5 1 1 6 6 6 5 Pentatricopeptide repeat domain PPR PF01535.20 RLN75910.1 - 7.2e-26 88.6 7.3 2.8e-07 30.3 0.1 12.3 12 1 0 12 12 12 4 PPR repeat PPR_1 PF12854.7 RLN75910.1 - 7.4e-20 70.3 4.1 9.5e-08 31.6 0.0 8.0 8 1 0 8 8 8 4 PPR repeat PPR_long PF17177.4 RLN75910.1 - 5.1e-15 55.4 4.1 0.00084 18.8 0.0 4.7 4 1 1 5 5 5 4 Pentacotripeptide-repeat region of PRORP COX5A PF02284.16 RLN75910.1 - 2.8e-05 24.0 0.1 0.19 11.8 0.0 4.3 2 1 2 4 4 4 1 Cytochrome c oxidase subunit Va ATP13 PF12921.7 RLN75910.1 - 0.0042 16.9 0.1 1.2 9.0 0.0 4.0 3 1 1 4 4 4 1 Mitochondrial ATPase expression Clathrin PF00637.20 RLN75910.1 - 0.013 15.4 1.2 6.3 6.7 0.1 4.6 5 0 0 5 5 5 0 Region in Clathrin and VPS SPOB_a PF14689.6 RLN75910.1 - 0.078 12.7 2.2 4.8 7.0 0.1 3.6 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain Coatomer_E PF04733.14 RLN75910.1 - 0.08 12.3 4.3 12 5.2 0.0 4.1 5 0 0 5 5 5 0 Coatomer epsilon subunit MRP-S27 PF10037.9 RLN75910.1 - 0.082 11.8 1.3 0.61 8.9 0.1 2.7 3 0 0 3 3 3 0 Mitochondrial 28S ribosomal protein S27 TPR_19 PF14559.6 RLN75910.1 - 1.7 9.2 8.4 20 5.8 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Uricase PF01014.18 RLN75911.1 - 2.7e-34 118.2 0.2 5.6e-24 84.9 0.1 2.9 1 1 1 2 2 2 2 Uricase Efg1 PF10153.9 RLN75929.1 - 0.059 13.7 1.2 28 5.1 0.0 3.5 3 0 0 3 3 3 0 rRNA-processing protein Efg1 Pox_A32 PF04665.12 RLN75930.1 - 8.2e-07 28.7 0.1 8.6e-05 22.1 0.1 2.1 1 1 0 1 1 1 1 Poxvirus A32 protein Cep57_CLD_2 PF14197.6 RLN75930.1 - 0.027 14.6 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 ResIII PF04851.15 RLN75930.1 - 0.045 13.7 0.0 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 RLN75930.1 - 0.097 12.7 0.0 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF1542 PF07564.11 RLN75931.1 - 0.095 12.8 1.6 0.32 11.1 1.6 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) YtxH PF12732.7 RLN75931.1 - 3.1 8.4 6.7 7.3 7.2 0.0 3.7 3 1 0 3 3 3 0 YtxH-like protein ABC2_membrane PF01061.24 RLN75940.1 - 1.2e-39 136.0 20.0 1.2e-39 136.0 20.0 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RLN75940.1 - 4e-14 53.3 0.0 6.3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 RLN75940.1 - 6.6e-07 28.8 13.2 6.6e-07 28.8 13.2 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 RLN75940.1 - 0.001 19.0 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_2 PF12679.7 RLN75940.1 - 0.0015 17.9 8.3 0.03 13.6 7.5 2.2 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 RLN75940.1 - 0.049 13.4 0.4 0.11 12.3 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN75940.1 - 0.13 12.7 0.3 0.24 11.9 0.3 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 RLN75940.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 RLN75940.1 - 0.15 12.6 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RLN75940.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Kelch_4 PF13418.6 RLN75961.1 - 2.6e-13 49.8 0.0 1.6e-06 28.0 0.0 5.5 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 RLN75961.1 - 9.2e-13 48.1 4.7 1.1e-05 25.6 0.2 5.6 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN75961.1 - 3.9e-12 45.9 0.0 0.024 14.6 0.0 5.8 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.6 RLN75961.1 - 4.6e-07 29.9 3.6 0.0059 16.9 0.0 5.2 4 2 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 RLN75961.1 - 1.2e-06 27.9 0.0 0.019 14.5 0.1 4.0 3 1 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 RLN75961.1 - 0.00067 19.5 0.9 6.9 6.8 0.1 4.4 4 1 0 4 4 4 2 Kelch motif TPP_enzyme_N PF02776.18 RLN75962.1 - 3.9e-56 189.3 0.0 9e-56 188.2 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 RLN75962.1 - 3.4e-43 146.7 1.2 5.6e-43 146.0 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Asparaginase_C PF17763.1 RLN75962.1 - 0.014 15.6 0.0 5.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain POR_N PF01855.19 RLN75962.1 - 0.021 14.5 0.2 0.058 13.1 0.2 1.9 2 1 0 2 2 2 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg CO_dh PF02552.16 RLN75962.1 - 0.023 14.5 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit LRR_9 PF14580.6 RLN75964.1 - 8e-51 172.0 0.2 1.2e-50 171.4 0.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeat SAP PF02037.27 RLN75964.1 - 1.1e-12 47.3 0.7 1.9e-12 46.6 0.7 1.4 1 0 0 1 1 1 1 SAP domain LRR_4 PF12799.7 RLN75964.1 - 5.9e-08 32.9 2.5 0.0018 18.6 0.2 3.6 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN75964.1 - 1.2e-07 31.4 4.5 5e-06 26.2 1.9 2.9 2 1 1 3 3 3 2 Leucine rich repeat TRAM_LAG1_CLN8 PF03798.16 RLN75964.1 - 0.00041 20.1 7.9 0.00069 19.4 7.9 1.3 1 0 0 1 1 1 1 TLC domain His_Phos_1 PF00300.22 RLN75965.1 - 1.2e-31 109.9 0.0 9.1e-15 54.9 0.0 2.7 2 1 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) LRR_8 PF13855.6 RLN75966.1 - 0.00072 19.3 0.4 0.075 12.8 0.5 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 RLN75966.1 - 0.11 13.0 0.1 3.6 8.1 0.1 2.8 2 1 0 3 3 3 0 Leucine Rich repeats (2 copies) bZIP_1 PF00170.21 RLN75967.1 - 2.9e-07 30.5 10.8 2.9e-07 30.5 10.8 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 RLN75967.1 - 0.00014 21.9 12.1 0.00014 21.9 12.1 2.2 2 0 0 2 2 2 1 Basic region leucine zipper LTXXQ PF07813.12 RLN75967.1 - 0.48 11.2 0.1 0.48 11.2 0.1 2.9 2 0 0 2 2 2 0 LTXXQ motif family protein AP-5_subunit_s1 PF15001.6 RLN75967.1 - 0.79 9.7 2.8 0.6 10.1 0.1 2.0 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 R3H PF01424.22 RLN75968.1 - 1.1e-05 25.3 0.1 2.5e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 R3H domain PH PF00169.29 RLN75969.1 - 2.1e-09 37.8 0.0 6.3e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 RLN75969.1 - 0.002 18.4 0.0 0.0041 17.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 RLN75969.1 - 0.082 13.3 2.5 0.4 11.1 0.1 3.2 3 1 0 3 3 3 0 Pleckstrin homology domain PriA_3primeBD PF17764.1 RLN75969.1 - 0.1 12.5 0.0 30 4.6 0.0 2.9 2 0 0 2 2 2 0 3′ DNA-binding domain (3′BD) UDPGP PF01704.18 RLN75978.1 - 3.4e-31 108.3 0.0 4e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase ZZ PF00569.17 RLN76004.1 - 1.3e-09 37.7 2.3 2.3e-09 36.9 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 RLN76004.1 - 0.014 15.7 5.4 0.025 14.9 5.4 1.4 1 0 0 1 1 1 0 C1 domain Exo_endo_phos PF03372.23 RLN76005.1 - 3.3e-19 69.3 0.0 4.7e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BTB PF00651.31 RLN76006.1 - 0.00032 20.9 0.0 0.52 10.6 0.1 3.4 3 1 0 3 3 3 2 BTB/POZ domain Sharpin_PH PF16764.5 RLN76006.1 - 0.12 12.1 0.2 0.38 10.5 0.2 1.8 1 0 0 1 1 1 0 Sharpin PH domain Mitofilin PF09731.9 RLN76013.1 - 0.11 11.4 10.7 0.11 11.3 10.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Pkinase PF00069.25 RLN76023.1 - 6.4e-25 88.0 0.0 8.1e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN76023.1 - 8.8e-24 84.2 0.0 1.1e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN76023.1 - 0.00015 21.8 2.5 0.00022 21.3 0.1 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 RLN76023.1 - 0.00061 19.4 0.0 0.0012 18.5 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 RLN76023.1 - 0.0089 14.8 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 RLN76023.1 - 0.009 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 RLN76023.1 - 0.22 10.8 0.0 0.39 10.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase zf-RanBP PF00641.18 RLN76031.1 - 0.00016 20.9 1.5 0.00028 20.1 1.5 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Pkinase PF00069.25 RLN76032.1 - 4e-58 196.9 0.0 4.9e-50 170.3 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN76032.1 - 8.1e-25 87.6 0.0 2.8e-22 79.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN76032.1 - 0.00015 21.2 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like GRP PF07172.11 RLN76032.1 - 4.5 8.0 8.1 15 6.3 8.1 1.9 1 0 0 1 1 1 0 Glycine rich protein family Sugar_tr PF00083.24 RLN76052.1 - 3.8e-50 171.1 20.6 5e-50 170.7 20.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN76052.1 - 4.9e-45 154.0 52.6 6.1e-41 140.5 33.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 RLN76052.1 - 0.00027 19.5 3.5 0.00027 19.5 3.5 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 RLN76052.1 - 0.0037 16.6 2.2 0.0037 16.6 2.2 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB BT1 PF03092.16 RLN76052.1 - 0.19 9.9 7.3 0.061 11.6 0.3 2.8 3 1 0 3 3 3 0 BT1 family RRN3 PF05327.11 RLN76053.1 - 0.032 12.8 0.1 0.036 12.6 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Voldacs PF03517.13 RLN76053.1 - 0.051 13.7 3.2 0.074 13.2 3.2 1.2 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Cwf_Cwc_15 PF04889.12 RLN76053.1 - 0.16 11.7 7.5 0.27 10.9 7.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 RLN76053.1 - 0.65 8.1 2.7 0.76 7.9 2.7 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 RLN76053.1 - 2.4 7.8 5.5 0.24 11.1 1.2 1.5 2 0 0 2 2 2 0 FAM176 family DNA_pol_phi PF04931.13 RLN76053.1 - 9.7 4.2 7.3 13 3.7 7.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Peptidase_M1 PF01433.20 RLN76074.1 - 9.3e-28 97.3 0.4 1.4e-27 96.7 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 RLN76074.1 - 2.4e-11 44.2 0.0 4.8e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF3458 PF11940.8 RLN76074.1 - 1e-09 38.7 0.0 2e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold DUF3458_C PF17432.2 RLN76074.1 - 1.9e-06 27.5 0.2 0.00018 21.0 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3458_C) ARM repeats Ribophorin_I PF04597.14 RLN76074.1 - 0.064 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribophorin I Sugar_tr PF00083.24 RLN76124.1 - 1e-05 24.7 0.0 1e-05 24.6 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter GCFC PF07842.12 RLN76125.1 - 2.6e-06 27.2 0.1 8.1e-06 25.6 0.1 1.9 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein Thg1C PF14413.6 RLN76125.1 - 0.044 14.0 0.5 0.11 12.7 0.5 1.6 1 0 0 1 1 1 0 Thg1 C terminal domain Peroxin-22 PF12827.7 RLN76159.1 - 0.03 14.2 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family TRAPP PF04051.16 RLN76160.1 - 1.1e-35 122.5 0.0 1.4e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Asp_Arg_Hydrox PF05118.15 RLN76161.1 - 4.2e-39 133.9 0.0 8e-39 133.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Methyltransf_11 PF08241.12 RLN76161.1 - 7.3e-16 58.6 0.0 1.4e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN76161.1 - 8.5e-14 51.6 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN76161.1 - 4.3e-13 49.8 0.0 9.4e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN76161.1 - 3.3e-11 43.8 0.0 6.9e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN76161.1 - 4.3e-10 39.7 0.0 7.6e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 RLN76161.1 - 5.2e-06 26.5 0.0 0.00042 20.2 0.0 2.2 2 0 0 2 2 2 1 Hypothetical methyltransferase MTS PF05175.14 RLN76161.1 - 6e-06 25.9 0.0 1.4e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 RLN76161.1 - 2.3e-05 23.9 0.0 3.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 RLN76161.1 - 0.0058 16.1 0.0 0.25 10.8 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase MetW PF07021.12 RLN76161.1 - 0.054 13.1 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF2764 PF10962.8 RLN76161.1 - 0.087 12.3 0.3 0.16 11.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) MFS_2 PF13347.6 RLN76163.1 - 4.8e-12 45.2 6.6 4.8e-12 45.2 6.6 2.5 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 RLN76163.1 - 0.091 11.6 11.0 0.58 9.0 5.7 2.4 2 1 0 2 2 2 0 MFS_1 like family EF-hand_6 PF13405.6 RLN76164.1 - 0.02 14.8 0.0 0.072 13.1 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain TPR_1 PF00515.28 RLN76165.1 - 1.2e-17 62.9 0.3 1.2e-05 24.9 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN76165.1 - 4.9e-16 57.5 1.5 0.00048 20.0 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat STI1 PF17830.1 RLN76165.1 - 4.5e-14 52.1 23.3 1e-09 38.1 1.0 3.6 3 0 0 3 3 3 2 STI1 domain TPR_11 PF13414.6 RLN76165.1 - 1.4e-10 40.7 0.4 0.0033 17.1 0.2 3.5 1 1 2 3 3 3 3 TPR repeat TPR_14 PF13428.6 RLN76165.1 - 1.1e-09 38.3 6.2 0.027 15.3 0.8 4.9 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN76165.1 - 8.9e-09 34.8 1.1 0.1 12.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 RLN76165.1 - 3e-07 31.0 8.9 8.3e-05 23.1 2.4 2.8 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN76165.1 - 3.8e-07 30.5 1.3 0.015 15.8 0.0 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN76165.1 - 4.9e-07 29.4 0.6 0.062 13.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN76165.1 - 5e-07 29.9 1.2 0.00011 22.5 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat SGT1 PF07093.11 RLN76165.1 - 8.2e-05 21.3 0.0 0.00013 20.6 0.0 1.2 1 0 0 1 1 1 1 SGT1 protein XPC-binding PF09280.11 RLN76165.1 - 0.0011 18.7 11.4 0.005 16.5 3.7 3.1 2 1 1 3 3 3 2 XPC-binding domain TPR_9 PF13371.6 RLN76165.1 - 0.0072 16.4 1.4 4.4 7.5 0.3 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat GerD PF17898.1 RLN76165.1 - 0.0093 15.9 5.7 0.0093 15.9 5.7 2.2 3 0 0 3 3 3 1 Spore germination GerD central core domain TPR_10 PF13374.6 RLN76165.1 - 0.011 15.6 7.1 5.1 7.1 0.6 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat VSG_B PF13206.6 RLN76165.1 - 0.013 14.8 1.2 0.019 14.2 1.2 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain TPR_17 PF13431.6 RLN76165.1 - 0.13 12.7 0.1 16 6.2 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat MAM33 PF02330.16 RLN76166.1 - 7.3e-41 140.4 6.5 8.8e-41 140.2 6.5 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Cwf_Cwc_15 PF04889.12 RLN76166.1 - 0.01 15.6 6.9 0.015 15.1 6.9 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 RLN76166.1 - 0.054 12.8 10.4 0.071 12.4 10.4 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2796 PF10986.8 RLN76166.1 - 0.092 12.7 3.8 0.15 12.0 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) GEN1_C PF18380.1 RLN76166.1 - 0.11 13.4 2.2 0.2 12.6 2.2 1.4 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain Nop14 PF04147.12 RLN76166.1 - 0.19 9.9 12.3 0.22 9.7 12.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RLN76166.1 - 0.35 9.1 4.8 0.41 8.9 4.8 1.3 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 RLN76166.1 - 0.38 10.1 6.7 0.42 10.0 6.7 1.2 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 RLN76166.1 - 1.1 8.8 8.8 1.3 8.5 8.8 1.1 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.13 RLN76166.1 - 5.1 5.1 16.0 7.1 4.6 16.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Prothymosin PF03247.14 RLN76166.1 - 5.4 7.5 19.9 0.28 11.6 13.9 1.9 3 0 0 3 3 2 0 Prothymosin/parathymosin family YL1 PF05764.13 RLN76166.1 - 8 6.5 10.8 11 6.1 10.8 1.3 1 0 0 1 1 1 0 YL1 nuclear protein CENP-B_dimeris PF09026.10 RLN76166.1 - 9.6 6.7 20.3 29 5.1 20.3 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Methyltransf_16 PF10294.9 RLN76167.1 - 3.8e-18 65.8 0.0 5.4e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 RLN76167.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain HEAT PF02985.22 RLN76169.1 - 0.23 11.8 0.1 0.23 11.8 0.1 4.7 5 0 0 5 5 5 0 HEAT repeat Glyco_hydro81C PF17652.1 RLN76170.1 - 4.6e-119 397.8 2.2 4.6e-119 397.8 2.2 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 RLN76170.1 - 2.1e-54 184.8 1.5 3.4e-54 184.2 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Ribonuc_L-PSP PF01042.21 RLN76172.1 - 3e-29 101.5 1.8 1.2e-11 44.7 0.0 4.2 4 0 0 4 4 4 3 Endoribonuclease L-PSP Diphthami_syn_2 PF01902.17 RLN76172.1 - 9.4e-11 41.6 0.0 2.8e-10 40.1 0.0 1.8 1 1 0 1 1 1 1 Diphthamide synthase CENP-N PF05238.13 RLN76172.1 - 0.13 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Ribosomal_L21e PF01157.18 RLN76173.1 - 2.2e-45 152.6 5.6 5.3e-45 151.4 5.6 1.7 1 0 0 1 1 1 1 Ribosomal protein L21e PIH1 PF08190.12 RLN76173.1 - 9e-12 44.8 0.0 2.3e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 PIH1 N-terminal domain Sec7 PF01369.20 RLN76174.1 - 3.3e-56 189.9 0.4 5.2e-56 189.2 0.4 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 RLN76174.1 - 3.3e-14 53.1 0.2 4.6e-13 49.4 0.0 3.1 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Fip1 PF05182.13 RLN76175.1 - 1.6e-23 81.9 0.4 2.8e-23 81.1 0.4 1.4 1 0 0 1 1 1 1 Fip1 motif FYVE PF01363.21 RLN76176.1 - 0.0042 17.2 14.9 0.0096 16.0 14.9 1.6 1 0 0 1 1 1 1 FYVE zinc finger zf-C2HE PF16278.5 RLN76176.1 - 0.035 14.6 0.2 0.14 12.6 0.1 2.1 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger ROS_MUCR PF05443.11 RLN76176.1 - 0.093 12.8 0.1 0.29 11.2 0.1 1.9 1 1 0 1 1 1 0 ROS/MUCR transcriptional regulator protein C1_1 PF00130.22 RLN76176.1 - 0.47 10.4 7.3 1.1 9.3 7.3 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 RLN76176.1 - 0.68 10.2 11.5 1.3 9.3 6.4 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger Zn-ribbon_8 PF09723.10 RLN76176.1 - 2.6 8.2 7.3 6.4 7.0 7.3 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Spt5_N PF11942.8 RLN76176.1 - 8.8 7.4 13.3 0.33 12.0 5.9 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Ank_4 PF13637.6 RLN76177.1 - 7.7e-42 141.1 24.8 4.8e-05 23.8 0.1 10.7 4 3 7 12 12 12 12 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN76177.1 - 7.9e-41 138.5 16.6 8.5e-09 35.9 0.1 7.1 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN76177.1 - 1e-38 130.8 28.8 0.011 16.1 0.1 14.2 4 3 11 15 15 15 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN76177.1 - 5.8e-19 66.2 11.2 11 6.9 0.0 13.9 13 2 2 15 15 15 4 Ankyrin repeat DUF5049 PF16468.5 RLN76177.1 - 4.2e-08 33.0 0.1 46 4.0 0.0 8.5 5 3 4 9 9 9 0 Domain of unknown function (DUF5049) Ank PF00023.30 RLN76177.1 - 1.2e-05 25.5 5.0 77 4.0 0.0 9.1 6 3 3 9 9 9 0 Ankyrin repeat VHL_C PF17211.3 RLN76177.1 - 0.0045 17.0 0.8 41 4.3 0.0 6.1 9 0 0 9 9 9 0 VHL box domain Ala_racemase_N PF01168.20 RLN76178.1 - 1e-18 67.8 0.1 1.2e-18 67.6 0.1 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain TetR_C_11 PF16859.5 RLN76180.1 - 0.24 11.7 3.1 0.21 11.9 0.7 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain MIS13 PF08202.11 RLN76181.1 - 0.00016 21.1 16.7 0.00016 21.1 16.7 5.3 2 1 1 4 4 4 1 Mis12-Mtw1 protein family DUF5076 PF16826.5 RLN76181.1 - 0.039 13.9 0.1 0.039 13.9 0.1 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5076) Adeno_PIX PF03955.14 RLN76181.1 - 0.22 11.7 2.5 0.8 9.9 2.5 2.0 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) CARM1 PF11531.8 RLN76181.1 - 0.48 10.6 3.4 1.4 9.1 0.1 3.4 2 0 0 2 2 2 0 Coactivator-associated arginine methyltransferase 1 N terminal MRP-L20 PF12824.7 RLN76191.1 - 0.00073 19.7 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 UPF0240 PF06784.11 RLN76191.1 - 0.00098 19.2 0.0 0.0013 18.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) Rnk_N PF14760.6 RLN76191.1 - 0.021 15.3 2.0 0.069 13.7 0.3 2.4 2 0 0 2 2 2 0 Rnk N-terminus Neugrin PF06413.11 RLN76191.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 2 0 0 2 2 2 0 Neugrin EST1_DNA_bind PF10373.9 RLN76192.1 - 2e-45 155.4 0.0 2.4e-44 151.9 0.0 2.3 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 RLN76192.1 - 4.5e-12 46.8 0.1 1.8e-11 44.8 0.0 2.0 2 0 0 2 2 2 1 Telomerase activating protein Est1 PA-IIL PF07472.11 RLN76192.1 - 0.15 12.4 0.1 0.35 11.2 0.1 1.5 1 0 0 1 1 1 0 Fucose-binding lectin II (PA-IIL) ScsC_N PF18312.1 RLN76192.1 - 0.18 11.6 0.3 0.49 10.3 0.3 1.7 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain MULE PF10551.9 RLN76194.1 - 4e-08 33.6 0.0 1.2e-07 32.0 0.0 1.8 2 0 0 2 2 2 1 MULE transposase domain VirionAssem_T7 PF11653.8 RLN76205.1 - 0.022 15.3 4.6 0.022 15.3 4.6 3.8 4 1 1 5 5 5 0 Bacteriophage T7 virion assembly protein DSPn PF14671.6 RLN76206.1 - 1.6e-17 64.2 0.0 2.8e-16 60.2 0.0 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 RLN76206.1 - 2.2e-16 59.9 0.0 5.8e-16 58.5 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RLN76206.1 - 7.8e-06 25.6 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 RLN76206.1 - 0.013 15.6 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate PRO8NT PF08082.11 RLN76206.1 - 0.044 13.7 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain Y_phosphatase3 PF13350.6 RLN76206.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family AA_permease_2 PF13520.6 RLN76216.1 - 9.8e-18 64.2 6.8 1.1e-17 64.0 6.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN76216.1 - 9.7e-12 44.2 5.7 1.4e-11 43.7 5.7 1.3 1 0 0 1 1 1 1 Amino acid permease Mannosyl_trans3 PF11051.8 RLN76217.1 - 2.8e-05 23.6 0.0 4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleo_P87 PF07267.11 RLN76217.1 - 4.4 6.1 8.0 5.3 5.8 8.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Mannosyl_trans3 PF11051.8 RLN76218.1 - 2.7e-29 102.4 0.0 1.5e-16 60.6 0.1 2.5 2 1 1 3 3 3 2 Mannosyltransferase putative AA_permease_2 PF13520.6 RLN76219.1 - 5.9e-09 35.2 17.4 7e-09 35.0 17.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN76219.1 - 0.0061 15.2 10.2 0.013 14.2 10.1 1.6 1 1 0 1 1 1 1 Amino acid permease Popeye PF04831.13 RLN76219.1 - 0.066 13.4 1.4 0.15 12.2 1.4 1.6 1 0 0 1 1 1 0 Popeye protein conserved region SpecificRecomb PF10136.9 RLN76219.1 - 0.068 11.5 1.8 0.095 11.0 1.8 1.1 1 0 0 1 1 1 0 Site-specific recombinase EamA PF00892.20 RLN76238.1 - 0.0027 17.9 4.7 0.0031 17.7 4.7 1.1 1 0 0 1 1 1 1 EamA-like transporter family TPT PF03151.16 RLN76238.1 - 0.015 14.7 0.9 0.017 14.4 0.9 1.0 1 0 0 1 1 1 0 Triose-phosphate Transporter family LapA_dom PF06305.11 RLN76238.1 - 0.18 11.7 1.8 11 6.0 0.6 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain WD40 PF00400.32 RLN76240.1 - 6.2e-42 140.8 23.0 7.8e-09 36.0 0.1 7.9 6 1 2 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN76240.1 - 8.5e-17 61.2 6.0 0.014 15.7 0.3 5.7 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 RLN76240.1 - 3.7e-05 22.0 5.7 0.00048 18.3 5.6 2.2 1 1 0 1 1 1 1 IKI3 family DUF2387 PF09526.10 RLN76240.1 - 0.007 16.5 1.2 3.3 7.9 0.1 3.5 3 0 0 3 3 3 1 Probable metal-binding protein (DUF2387) Gmad1 PF10647.9 RLN76240.1 - 0.01 15.6 5.3 0.19 11.4 2.2 3.9 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain SH3_9 PF14604.6 RLN76240.1 - 0.21 11.4 1.3 0.52 10.2 0.2 2.1 2 0 0 2 2 2 0 Variant SH3 domain WD40_like PF17005.5 RLN76240.1 - 0.24 10.7 0.0 21 4.3 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain Homeodomain PF00046.29 RLN76241.1 - 9.6e-05 22.2 3.4 0.037 13.9 0.7 2.8 2 1 0 2 2 2 2 Homeodomain RXT2_N PF08595.11 RLN76241.1 - 8.4 6.4 12.8 6.2 6.8 5.9 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal TPR_16 PF13432.6 RLN76242.1 - 3.2e-07 30.9 1.6 4.7e-05 24.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN76242.1 - 0.0001 21.9 0.4 0.00034 20.2 0.1 2.0 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 RLN76242.1 - 0.00052 19.9 0.0 0.015 15.3 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN76242.1 - 0.00067 19.8 0.0 0.0018 18.4 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN76242.1 - 0.0011 19.2 0.0 0.0081 16.5 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN76242.1 - 0.0016 19.1 0.8 0.079 13.8 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN76242.1 - 0.038 13.8 0.0 0.23 11.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 RLN76242.1 - 0.17 12.2 0.0 0.85 10.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat IQ PF00612.27 RLN76243.1 - 1.1e-13 49.7 40.6 0.0083 15.8 0.1 7.8 7 0 0 7 7 7 7 IQ calmodulin-binding motif Pkinase_Tyr PF07714.17 RLN76267.1 - 3.6e-56 190.3 0.0 5.2e-43 147.2 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN76267.1 - 6.5e-50 169.9 0.0 2.6e-37 128.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Arm PF00514.23 RLN76267.1 - 2.1e-21 75.2 8.2 0.0067 16.4 0.0 9.8 10 0 0 10 10 10 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN76267.1 - 3e-08 34.0 13.4 0.0076 16.7 1.4 5.7 4 2 1 5 5 5 4 HEAT-like repeat HEAT_2 PF13646.6 RLN76267.1 - 5.2e-06 26.8 20.0 0.0069 16.8 0.3 5.4 3 2 0 4 4 4 2 HEAT repeats HEAT PF02985.22 RLN76267.1 - 0.00019 21.4 5.6 5.4 7.5 0.0 6.0 6 0 0 6 6 5 2 HEAT repeat Kinase-like PF14531.6 RLN76267.1 - 0.026 13.8 0.0 1.1 8.5 0.0 2.5 2 0 0 2 2 2 0 Kinase-like MoaE PF02391.17 RLN76267.1 - 0.077 13.3 0.0 77 3.6 0.0 4.4 3 1 1 4 4 4 0 MoaE protein Pkinase_fungal PF17667.1 RLN76267.1 - 0.089 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 RLN76267.1 - 0.11 11.9 0.0 2.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN76267.1 - 2.1 8.2 6.8 2.6 7.9 0.0 3.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 RLN76268.1 - 4.2e-34 118.0 0.0 5.5e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN76268.1 - 3.5e-31 108.5 0.0 5.3e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 RLN76268.1 - 0.00049 19.0 0.0 0.00087 18.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN76268.1 - 0.024 14.5 0.1 0.042 13.8 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN76268.1 - 0.21 10.9 0.4 0.43 9.9 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 RLN76291.1 - 7e-76 254.9 0.0 7.1e-41 140.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN76291.1 - 6.8e-66 222.3 0.0 6.9e-32 110.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain DZR PF12773.7 RLN76291.1 - 4e-09 36.4 7.8 1e-08 35.1 7.8 1.8 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 RLN76291.1 - 5.2e-08 33.5 3.8 0.0054 17.4 0.7 2.5 2 0 0 2 2 2 2 zinc-ribbon family APH PF01636.23 RLN76291.1 - 2e-06 27.9 5.2 0.028 14.3 0.2 3.8 2 1 0 3 3 3 2 Phosphotransferase enzyme family UPF0547 PF10571.9 RLN76291.1 - 6.1e-06 26.2 7.5 0.00075 19.5 1.8 2.9 2 0 0 2 2 2 2 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.6 RLN76291.1 - 2.6e-05 23.7 6.9 0.0062 16.2 1.2 3.0 2 0 0 2 2 2 2 zinc-ribbon domain zf-ribbon_3 PF13248.6 RLN76291.1 - 0.00011 21.5 1.0 0.00011 21.5 1.0 3.2 3 0 0 3 3 3 1 zinc-ribbon domain Kdo PF06293.14 RLN76291.1 - 0.00019 20.8 0.1 0.051 12.9 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RLN76291.1 - 0.0041 16.7 0.0 0.83 9.2 0.0 2.5 2 0 0 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 RLN76291.1 - 0.11 11.4 0.0 7.9 5.3 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 RLN76291.1 - 0.15 11.3 0.0 14 4.9 0.0 2.3 2 0 0 2 2 2 0 Kinase-like EcKinase PF02958.20 RLN76291.1 - 0.21 10.9 0.0 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 Ecdysteroid kinase PH PF00169.29 RLN76360.1 - 5.3e-08 33.3 0.0 1.6e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 PH domain WW PF00397.26 RLN76360.1 - 2.2e-07 30.8 2.0 2.2e-07 30.8 2.0 1.8 2 0 0 2 2 2 1 WW domain Spc7 PF08317.11 RLN76360.1 - 9.9e-05 21.4 9.3 9.9e-05 21.4 9.3 11.5 4 2 7 12 12 12 1 Spc7 kinetochore protein PH_8 PF15409.6 RLN76360.1 - 0.022 15.0 0.1 0.19 12.0 0.1 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 RLN76360.1 - 0.052 14.0 0.2 0.49 10.8 0.0 3.0 2 0 0 2 2 2 0 Pleckstrin homology domain Glyco_hyd_101C PF17451.2 RLN76360.1 - 0.1 12.9 0.1 0.47 10.7 0.1 2.2 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain HTH_Tnp_Tc5 PF03221.16 RLN76361.1 - 5.2e-09 36.0 0.3 1.6e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_Tnp_1 PF01527.20 RLN76361.1 - 4.8e-07 30.0 2.9 4e-06 27.0 0.9 2.5 1 1 1 2 2 2 1 Transposase HTH_23 PF13384.6 RLN76361.1 - 4e-05 23.3 1.1 0.0001 22.0 1.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 RLN76361.1 - 0.0011 19.1 2.0 0.0018 18.4 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain TnsD PF15978.5 RLN76361.1 - 0.0016 17.5 1.1 0.0029 16.7 1.1 1.3 1 0 0 1 1 1 1 Tn7-like transposition protein D HTH_29 PF13551.6 RLN76361.1 - 0.0022 18.0 0.1 0.0091 16.0 0.1 2.2 1 0 0 1 1 1 1 Winged helix-turn helix CENP-B_N PF04218.13 RLN76361.1 - 0.013 15.1 0.1 0.03 14.0 0.1 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain MerR_1 PF13411.6 RLN76361.1 - 0.052 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 MerR HTH family regulatory protein DUF1192 PF06698.11 RLN76362.1 - 0.7 10.0 10.6 0.51 10.4 1.4 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) SseC PF04888.12 RLN76362.1 - 4.7 6.7 29.9 0.028 14.0 2.7 3.0 1 1 2 3 3 3 0 Secretion system effector C (SseC) like family RNase_J_C PF17770.1 RLN76362.1 - 9.8 7.3 7.6 4.8 8.3 0.1 3.4 3 0 0 3 3 3 0 Ribonuclease J C-terminal domain fn3 PF00041.21 RLN76363.1 - 4.7e-06 26.9 0.0 0.00013 22.2 0.0 2.3 1 1 0 1 1 1 1 Fibronectin type III domain Ank_2 PF12796.7 RLN76363.1 - 0.0015 19.1 0.0 0.2 12.3 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN76363.1 - 0.0053 17.0 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN76363.1 - 0.067 13.8 0.0 0.4 11.4 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat T2SSB PF16537.5 RLN76363.1 - 0.18 11.4 0.0 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system protein B MFS_1 PF07690.16 RLN76364.1 - 2.4e-31 109.0 23.5 2.8e-31 108.8 23.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 RLN76364.1 - 7.6e-06 25.0 3.4 0.00014 20.9 3.4 2.3 1 1 0 1 1 1 1 MFS_1 like family ATG22 PF11700.8 RLN76364.1 - 0.00013 20.8 6.9 0.004 15.9 0.2 2.2 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like Sugar_tr PF00083.24 RLN76364.1 - 0.00018 20.5 6.2 0.00018 20.5 6.2 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 RLN76364.1 - 0.11 10.9 15.3 0.1 11.0 5.0 2.3 2 1 0 2 2 2 0 Transmembrane secretion effector Beta-APP PF03494.13 RLN76364.1 - 0.2 11.5 1.1 17 5.4 0.5 2.5 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) tRNA-synt_His PF13393.6 RLN76365.1 - 4.6e-42 144.4 0.0 4.6e-42 144.4 0.0 2.7 2 1 1 3 3 3 1 Histidyl-tRNA synthetase Lyase_aromatic PF00221.19 RLN76365.1 - 7.8e-21 74.3 23.1 1.3e-20 73.5 23.1 1.3 1 0 0 1 1 1 1 Aromatic amino acid lyase HGTP_anticodon PF03129.20 RLN76365.1 - 1.1e-16 60.8 0.0 2.4e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 RLN76365.1 - 3.6e-08 33.2 0.0 3.6e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 RLN76365.1 - 0.00049 19.3 0.0 0.001 18.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF498 PF04430.14 RLN76365.1 - 0.071 13.2 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) DUF1682 PF07946.14 RLN76365.1 - 0.11 11.6 15.7 0.19 10.9 15.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Presenilin PF01080.17 RLN76365.1 - 0.37 9.5 2.1 0.55 8.9 2.1 1.1 1 0 0 1 1 1 0 Presenilin THOC2_N PF16134.5 RLN76365.1 - 2.9 6.4 10.1 4.4 5.8 10.1 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Pinin_SDK_memA PF04696.13 RLN76365.1 - 3 7.9 14.0 5.4 7.1 14.0 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF4355 PF14265.6 RLN76365.1 - 8.4 6.6 26.0 27 5.0 26.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Glyco_hydro_12 PF01670.16 RLN76366.1 - 1.3e-43 149.5 3.8 1.5e-43 149.3 3.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 ABC2_membrane PF01061.24 RLN76367.1 - 8.7e-36 123.3 25.2 8.7e-36 123.3 25.2 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RLN76367.1 - 3.6e-27 95.5 0.0 5.6e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN76367.1 - 5.8e-10 39.5 0.0 0.00085 19.2 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN76367.1 - 5.3e-05 23.7 0.0 9.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 RLN76367.1 - 0.00013 21.6 0.1 0.00042 20.0 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN76367.1 - 0.00018 21.5 0.0 0.00031 20.7 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 RLN76367.1 - 0.0013 18.2 0.1 1.6 8.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RLN76367.1 - 0.0013 19.3 0.1 0.0023 18.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 RLN76367.1 - 0.0098 15.8 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 RLN76367.1 - 0.011 15.9 0.2 0.06 13.6 0.2 2.2 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 RLN76367.1 - 0.13 12.4 0.1 0.39 10.8 0.1 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 RLN76367.1 - 0.2 11.2 0.2 0.45 10.1 0.1 1.6 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 RLN76367.1 - 0.37 9.8 28.2 0.22 10.6 26.2 1.6 1 1 1 2 2 2 0 ABC-2 family transporter protein Cob_adeno_trans PF01923.18 RLN76368.1 - 1.1e-56 191.5 0.0 1.4e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 Cobalamin adenosyltransferase MFS_1 PF07690.16 RLN76369.1 - 3.7e-24 85.3 73.0 2.7e-15 56.1 30.7 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Myb_DNA-binding PF00249.31 RLN76392.1 - 2.7e-09 37.1 0.1 7.6e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 RLN76393.1 - 3.5e-11 43.1 0.1 9.1e-11 41.8 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF4200 PF13863.6 RLN76393.1 - 0.014 15.7 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4452 PF14618.6 RLN76393.1 - 4.6 7.1 9.0 12 5.7 9.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4452) Peptidase_S9 PF00326.21 RLN76394.1 - 7.8e-53 179.1 0.0 9.1e-51 172.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 RLN76394.1 - 1.2e-41 142.9 0.0 1.7e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Esterase PF00756.20 RLN76394.1 - 0.0029 17.3 0.1 0.0091 15.7 0.0 1.8 2 0 0 2 2 2 1 Putative esterase R2K_2 PF18299.1 RLN76394.1 - 0.025 14.5 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 F-box-like PF12937.7 RLN76394.1 - 0.035 14.0 0.4 0.39 10.7 0.1 2.6 2 0 0 2 2 2 0 F-box-like TPR_MLP1_2 PF07926.12 RLN76394.1 - 4.1 7.5 5.9 2 8.5 1.7 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Myosin_head PF00063.21 RLN76395.1 - 9.5e-222 737.9 0.0 1.1e-221 737.7 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 RLN76395.1 - 9.4e-07 28.1 37.2 0.0046 16.6 4.3 5.2 5 0 0 5 5 5 4 IQ calmodulin-binding motif AAA_16 PF13191.6 RLN76395.1 - 0.019 15.4 0.6 0.086 13.2 0.1 2.5 3 1 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 RLN76395.1 - 0.034 14.4 0.0 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 RLN76395.1 - 0.11 11.8 1.8 0.16 11.2 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin Myosin_N PF02736.19 RLN76395.1 - 0.17 11.7 0.2 0.41 10.5 0.0 1.7 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain AAA_28 PF13521.6 RLN76395.1 - 0.45 10.7 2.7 1.6 9.0 0.4 2.5 2 0 0 2 2 2 0 AAA domain PI-PLC-C1 PF16670.5 RLN76396.1 - 0.013 14.6 0.0 0.041 12.9 0.0 1.7 2 0 0 2 2 2 0 Phosphoinositide phospholipase C, Ca2+-dependent Myb_DNA-binding PF00249.31 RLN76397.1 - 5.8e-12 45.6 0.0 9.6e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN76397.1 - 0.021 15.1 0.0 0.055 13.7 0.0 1.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 RLN76398.1 - 5.4e-12 45.7 0.1 8.1e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain VPS9 PF02204.18 RLN76399.1 - 7e-11 42.3 0.1 1.3e-10 41.4 0.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF726 PF05277.12 RLN76399.1 - 4.3 6.2 6.4 7.1 5.5 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Zip PF02535.22 RLN76409.1 - 5.2e-26 91.7 4.7 1.4e-25 90.2 4.7 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter Cu-oxidase_3 PF07732.15 RLN76409.1 - 3.8e-12 46.3 1.9 2.7e-07 30.6 0.1 3.5 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 RLN76409.1 - 4.2e-12 46.0 3.9 1.4e-11 44.3 3.9 1.9 1 1 0 1 1 1 1 Multicopper oxidase LEP503 PF15221.6 RLN76409.1 - 0.034 14.5 0.1 0.077 13.3 0.1 1.6 1 0 0 1 1 1 0 Lens epithelial cell protein LEP503 TFR_dimer PF04253.15 RLN76419.1 - 1e-31 109.5 0.0 1.6e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 RLN76419.1 - 2.5e-19 69.8 0.0 6.4e-19 68.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 FYVE PF01363.21 RLN76420.1 - 8.1e-12 45.1 10.8 1.8e-11 44.0 10.8 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN76420.1 - 0.0052 17.0 5.5 0.01 16.1 5.5 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger CCDC144C PF14915.6 RLN76420.1 - 0.015 14.4 0.6 0.029 13.5 0.6 1.3 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region zf-HIT PF04438.16 RLN76420.1 - 10 6.1 8.2 23 5.0 8.2 1.7 1 0 0 1 1 1 0 HIT zinc finger Pkinase_Tyr PF07714.17 RLN76437.1 - 2.5e-40 138.4 0.0 3.4e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN76437.1 - 9.7e-40 136.6 0.0 1.3e-39 136.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 RLN76437.1 - 0.04 12.7 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Aa_trans PF01490.18 RLN76439.1 - 0.00081 18.2 0.2 0.001 17.8 0.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TctA PF01970.16 RLN76439.1 - 0.014 14.1 0.1 0.017 13.9 0.1 1.0 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family DUF420 PF04238.12 RLN76439.1 - 0.042 14.1 0.0 0.047 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF420) NAP PF00956.18 RLN76465.1 - 2.6e-09 36.6 5.4 2.6e-09 36.6 5.4 3.7 3 1 0 3 3 3 1 Nucleosome assembly protein (NAP) Plk4_PB2 PF18409.1 RLN76465.1 - 0.026 15.2 0.1 2.3 8.9 0.0 3.0 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Bile_Hydr_Trans PF04775.14 RLN76465.1 - 0.062 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region DASH_Duo1 PF08651.10 RLN76465.1 - 3 7.7 6.0 0.95 9.3 2.7 1.9 2 0 0 2 2 2 0 DASH complex subunit Duo1 SPC12 PF06645.13 RLN76466.1 - 1.3e-22 79.7 1.4 1.5e-22 79.5 1.4 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Nop53 PF07767.11 RLN76469.1 - 0.0084 15.5 24.7 0.019 14.4 3.0 2.4 2 0 0 2 2 2 2 Nop53 (60S ribosomal biogenesis) Peptidase_C97 PF05903.14 RLN76470.1 - 1.6e-26 93.0 0.0 2.9e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain cNMP_binding PF00027.29 RLN76470.1 - 1.6e-12 47.3 0.7 6.7e-12 45.3 0.1 2.3 3 0 0 3 3 3 1 Cyclic nucleotide-binding domain AAA_16 PF13191.6 RLN76470.1 - 0.00034 21.0 0.0 0.0016 18.9 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RLN76470.1 - 0.0025 18.1 0.0 0.01 16.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 RLN76470.1 - 0.028 13.8 0.0 0.057 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_33 PF13671.6 RLN76470.1 - 0.029 14.5 0.0 0.076 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RLN76470.1 - 0.058 13.0 0.0 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 RLN76470.1 - 0.061 13.2 0.1 0.97 9.3 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Ploopntkinase3 PF18751.1 RLN76470.1 - 0.07 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_30 PF13604.6 RLN76470.1 - 0.075 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 RLN76470.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 RLN76470.1 - 0.15 11.3 0.0 0.34 10.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Dimer_Tnp_hAT PF05699.14 RLN76471.1 - 0.0013 18.4 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Med26 PF08711.11 RLN76473.1 - 1.8e-13 50.2 0.8 4.6e-13 49.0 0.8 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DEK_C PF08766.11 RLN76473.1 - 1.7e-07 31.1 0.3 3.1e-07 30.2 0.3 1.5 1 0 0 1 1 1 1 DEK C terminal domain HTH_33 PF13592.6 RLN76473.1 - 0.3 10.8 3.6 0.61 9.8 0.2 2.5 2 0 0 2 2 2 0 Winged helix-turn helix LacI PF00356.21 RLN76473.1 - 0.47 10.3 0.1 0.47 10.3 0.1 2.8 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family DUF1688 PF07958.11 RLN76509.1 - 2.9e-136 454.6 0.0 3.2e-132 441.2 0.0 3.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1688) Ribosomal_S30 PF04758.14 RLN76538.1 - 1e-28 99.3 6.0 1.3e-28 99.0 6.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 ubiquitin PF00240.23 RLN76538.1 - 0.016 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family MTHFR PF02219.17 RLN76538.1 - 0.055 12.8 0.1 0.068 12.5 0.1 1.1 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase DivIC PF04977.15 RLN76539.1 - 0.012 15.3 4.2 0.012 15.3 4.2 6.6 4 2 3 7 7 7 0 Septum formation initiator NPV_P10 PF05531.12 RLN76539.1 - 1.2 9.6 4.0 5 7.7 0.3 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 RLN76539.1 - 1.2 7.9 69.9 0.025 13.5 22.5 3.8 1 1 3 4 4 4 0 Spc7 kinetochore protein FYVE PF01363.21 RLN76540.1 - 1.7e-13 50.5 12.9 3.2e-13 49.6 12.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 RLN76540.1 - 1.8e-05 24.2 0.1 4.4e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 START domain FYVE_2 PF02318.16 RLN76540.1 - 0.31 11.3 8.2 0.62 10.3 8.2 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger YABBY PF04690.13 RLN76540.1 - 6.5 7.3 8.3 1.5 9.3 3.2 2.4 2 0 0 2 2 2 0 YABBY protein XPG_I PF00867.18 RLN76560.1 - 1.3e-17 63.9 0.0 1.8e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 RLN76560.1 - 0.0005 19.6 0.0 0.00056 19.5 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.17 RLN76560.1 - 0.00081 19.8 0.0 0.0013 19.1 0.0 1.4 1 1 0 1 1 1 1 XPG N-terminal domain Anillin_N PF16018.5 RLN76561.1 - 0.1 13.2 0.6 0.1 13.2 0.6 2.2 2 1 1 3 3 3 0 Anillin N-terminus Nha1_C PF08619.10 RLN76561.1 - 0.75 8.9 7.9 0.69 9.1 7.9 1.2 1 1 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus ADH_zinc_N_2 PF13602.6 RLN76562.1 - 0.0098 16.9 0.1 0.019 16.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase C2 PF00168.30 RLN76578.1 - 4.1e-10 39.9 0.0 7.8e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain FimA PF16970.5 RLN76578.1 - 0.038 14.2 0.0 0.077 13.2 0.0 1.5 1 0 0 1 1 1 0 Type-1 fimbrial protein, A C2 PF00168.30 RLN76579.1 - 2.2e-12 47.1 0.0 4e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain IGPD PF00475.18 RLN76579.1 - 0.084 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Imidazoleglycerol-phosphate dehydratase Pkinase_Tyr PF07714.17 RLN76599.1 - 9e-38 130.0 0.0 1.8e-37 129.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN76599.1 - 8.6e-32 110.5 0.0 2.7e-31 108.9 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain zinc_ribbon_15 PF17032.5 RLN76599.1 - 0.0038 17.9 0.5 0.013 16.3 0.5 1.9 1 0 0 1 1 1 1 zinc-ribbon family DZR PF12773.7 RLN76599.1 - 0.0078 16.2 0.6 0.021 14.8 0.6 1.7 1 0 0 1 1 1 1 Double zinc ribbon DUF2605 PF10792.9 RLN76599.1 - 0.024 14.5 0.8 14 5.7 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2605) zf-NADH-PPase PF09297.11 RLN76599.1 - 0.16 11.7 3.2 2.8 7.7 0.6 2.7 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Rad50_zn_hook PF04423.14 RLN76599.1 - 0.44 10.4 0.1 0.44 10.4 0.1 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif SesA PF17107.5 RLN76599.1 - 0.99 9.6 5.2 1.2 9.4 0.1 3.2 4 0 0 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TniQ PF06527.11 RLN76599.1 - 1.3 9.7 3.7 1.4 9.6 0.1 2.6 3 1 0 3 3 3 0 TniQ HSF_DNA-bind PF00447.17 RLN76612.1 - 1.8e-06 28.5 0.1 5.2e-06 27.0 0.0 1.8 2 1 0 2 2 2 1 HSF-type DNA-binding Ank_2 PF12796.7 RLN76613.1 - 1.2e-26 93.1 0.2 2.1e-14 53.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN76613.1 - 1.2e-25 89.6 2.7 2.5e-09 37.5 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN76613.1 - 5e-22 75.6 4.0 0.00013 22.1 0.1 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 RLN76613.1 - 4.4e-20 71.2 9.9 0.00027 21.2 0.4 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 RLN76613.1 - 5.9e-16 58.3 5.1 1.2e-05 25.4 0.0 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) FAD-oxidase_C PF02913.19 RLN76613.1 - 0.085 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain PAP2_C PF14360.6 RLN76614.1 - 3.5e-22 78.7 6.5 3.5e-22 78.7 6.5 2.0 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2_3 PF14378.6 RLN76614.1 - 3e-05 23.8 6.3 5.7e-05 22.9 6.3 1.6 1 1 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 RLN76614.1 - 3.6e-05 23.5 2.2 5.6e-05 22.9 2.2 1.4 1 1 0 1 1 1 1 PAP2 superfamily GPI2 PF06432.11 RLN76614.1 - 1.3 8.4 8.4 0.28 10.6 1.7 2.1 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase BCDHK_Adom3 PF10436.9 RLN76615.1 - 1.8e-26 92.9 0.0 2.6e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 RLN76615.1 - 3.7e-05 24.2 0.0 6.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_22 PF13401.6 RLN76626.1 - 0.003 17.8 0.1 0.094 13.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RLN76626.1 - 0.033 14.4 0.1 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 RLN76626.1 - 0.035 14.5 0.2 0.12 12.8 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain Ribosomal_60s PF00428.19 RLN76626.1 - 0.1 13.2 0.2 0.1 13.2 0.2 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein Sld5 PF05916.11 RLN76627.1 - 4.3e-09 36.8 0.0 5.9e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein DUF4203 PF13886.6 RLN76628.1 - 1e-06 28.5 0.2 1.1e-06 28.5 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) SAT PF16073.5 RLN76648.1 - 5.5e-23 81.9 0.8 5.5e-23 81.9 0.8 1.7 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Mucin PF01456.17 RLN76648.1 - 0.69 9.9 26.6 0.29 11.1 24.0 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Fumble PF03630.14 RLN76674.1 - 6.8e-110 367.3 0.0 4.6e-94 315.3 0.0 2.1 2 0 0 2 2 2 2 Fumble cNMP_binding PF00027.29 RLN76677.1 - 2.9e-44 149.0 0.3 1.5e-12 47.4 0.0 6.7 6 0 0 6 6 6 6 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN76677.1 - 1.4e-17 63.7 45.0 4.5e-06 26.1 2.8 4.4 4 0 0 4 4 4 4 Ion transport protein Ion_trans_2 PF07885.16 RLN76677.1 - 2.9e-10 40.0 37.9 0.00012 22.0 3.7 5.5 5 0 0 5 5 5 3 Ion channel DUF485 PF04341.12 RLN76677.1 - 1.9 8.5 6.2 0.52 10.3 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function, DUF485 PXA PF02194.15 RLN76678.1 - 2.8e-25 89.3 0.0 8.1e-25 87.9 0.0 1.9 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 RLN76678.1 - 5.4e-15 55.9 0.0 2.3e-14 53.9 0.0 2.2 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 RLN76678.1 - 3.1e-07 30.3 0.0 1.2e-06 28.5 0.0 2.0 1 0 0 1 1 1 1 PX domain RUN PF02759.19 RLN76678.1 - 0.023 14.7 0.6 0.18 11.8 0.0 2.4 2 0 0 2 2 2 0 RUN domain FYVE_2 PF02318.16 RLN76678.1 - 0.053 13.7 3.1 0.18 12.0 3.1 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 RLN76678.1 - 0.18 11.9 9.9 0.019 15.1 5.1 1.9 2 0 0 2 2 2 0 FYVE zinc finger DUF3246 PF11596.8 RLN76678.1 - 4.5 6.6 8.4 1.5 8.2 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Ribosomal_L3 PF00297.22 RLN76679.1 - 3.2e-17 62.6 4.8 5.6e-15 55.2 1.2 2.4 2 1 1 3 3 3 2 Ribosomal protein L3 Sugar_tr PF00083.24 RLN76691.1 - 3.1e-91 306.5 21.9 3.8e-91 306.2 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN76691.1 - 3.2e-27 95.4 26.1 3.2e-27 95.4 26.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 RLN76691.1 - 8.3e-06 24.5 1.5 8.3e-06 24.5 1.5 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3188 PF11384.8 RLN76691.1 - 0.0031 17.2 0.6 0.0031 17.2 0.6 4.2 4 0 0 4 4 4 1 Protein of unknown function (DUF3188) MFS_3 PF05977.13 RLN76691.1 - 0.2 10.0 11.2 0.27 9.6 3.2 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Sugar_tr PF00083.24 RLN76692.1 - 1.1e-96 324.4 18.9 1.4e-96 324.2 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN76692.1 - 1e-27 97.0 30.6 1.9e-23 83.0 25.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CytB6-F_Fe-S PF08802.10 RLN76692.1 - 0.7 10.0 8.2 2.6 8.2 0.2 3.1 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit DUF2583 PF10762.9 RLN76692.1 - 1.2 9.6 8.7 1.1 9.7 4.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) Sugar_tr PF00083.24 RLN76693.1 - 5.6e-92 309.0 19.0 9.8e-92 308.2 19.0 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN76693.1 - 2e-25 89.5 27.6 2e-25 89.5 27.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 RLN76693.1 - 2e-06 26.5 2.3 2e-06 26.5 2.3 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 RLN76694.1 - 3.8e-22 78.8 0.0 4.7e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Cellulase PF00150.18 RLN76706.1 - 3.7e-29 102.1 0.1 5.6e-29 101.4 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) BCAS2 PF05700.11 RLN76707.1 - 1.7e-25 89.9 11.6 2e-25 89.7 11.6 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) SNARE PF05739.19 RLN76707.1 - 0.45 10.5 4.7 1.2 9.1 0.1 2.8 2 1 1 3 3 3 0 SNARE domain Peptidase_M13 PF01431.21 RLN76708.1 - 6.1e-65 218.7 2.3 6.9e-65 218.5 2.3 1.0 1 0 0 1 1 1 1 Peptidase family M13 Dynamin_N PF00350.23 RLN76731.1 - 8e-10 39.0 0.0 2.3e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 RLN76731.1 - 5e-07 29.8 0.0 4.5e-06 26.7 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RLN76731.1 - 5.9e-05 23.5 0.6 0.00039 20.8 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain CBM-like PF14683.6 RLN76731.1 - 0.0013 18.6 0.1 0.0026 17.7 0.1 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III RsgA_GTPase PF03193.16 RLN76731.1 - 0.0014 18.6 0.0 0.18 11.7 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 RLN76731.1 - 0.005 16.2 0.0 0.02 14.2 0.0 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region cobW PF02492.19 RLN76731.1 - 0.016 14.8 0.1 0.16 11.5 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 RLN76731.1 - 0.1 12.0 0.0 15 4.9 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Endonuc-BglII PF09195.11 RLN76731.1 - 0.11 12.4 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Restriction endonuclease BglII LSM14 PF12701.7 RLN76811.1 - 1.2e-26 92.6 0.0 2.1e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 RLN76811.1 - 4.6e-06 27.5 0.1 4.6e-06 27.5 0.1 2.6 2 1 1 3 3 3 1 FDF domain SM-ATX PF14438.6 RLN76811.1 - 0.011 15.8 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain TFIIA PF03153.13 RLN76811.1 - 6.3 6.7 13.3 7.6 6.4 13.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Carb_anhydrase PF00194.21 RLN76813.1 - 1.6e-33 116.4 0.0 3.3e-33 115.3 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DHC_N2 PF08393.13 RLN76814.1 - 7.8e-64 216.2 0.1 7.8e-64 216.2 0.1 3.1 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 MT PF12777.7 RLN76814.1 - 2.2e-14 53.3 2.0 4.6e-14 52.2 2.0 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 RLN76814.1 - 1.1e-13 51.1 0.0 1.5e-06 27.8 0.0 4.4 4 0 0 4 4 4 3 P-loop containing dynein motor region AAA_6 PF12774.7 RLN76814.1 - 5.2e-06 25.7 0.0 0.0037 16.3 0.0 2.6 2 1 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 RLN76814.1 - 0.00032 20.7 0.1 0.5 10.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 RLN76814.1 - 0.0035 17.4 0.0 0.02 15.0 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_8 PF12780.7 RLN76814.1 - 0.0036 16.7 0.0 0.01 15.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_18 PF13238.6 RLN76814.1 - 0.032 14.8 0.0 0.41 11.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 RLN76814.1 - 0.06 13.3 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 RLN76814.1 - 0.069 13.4 0.0 0.5 10.6 0.0 2.6 1 0 0 1 1 1 0 AAA domain AAA_lid_1 PF17857.1 RLN76814.1 - 0.1 12.8 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA+ lid domain RsgA_GTPase PF03193.16 RLN76814.1 - 0.42 10.5 2.2 0.65 9.9 0.0 2.5 3 0 0 3 3 2 0 RsgA GTPase ING PF12998.7 RLN76814.1 - 7.2 7.3 9.4 0.69 10.5 0.6 3.4 3 0 0 3 3 2 0 Inhibitor of growth proteins N-terminal histone-binding zf-C2H2 PF00096.26 RLN76850.1 - 5.2e-33 111.7 59.6 2.4e-05 24.5 1.7 8.7 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN76850.1 - 1e-26 91.3 51.3 0.0016 19.1 0.8 8.8 8 0 0 8 8 8 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RLN76850.1 - 3e-18 65.3 66.3 4.5e-06 26.8 2.1 10.5 11 0 0 11 11 10 5 Zinc-finger double domain zf-H2C2_5 PF13909.6 RLN76850.1 - 2e-08 33.8 38.4 0.15 11.8 1.0 8.3 8 0 0 8 8 8 6 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 RLN76850.1 - 1.6e-06 27.9 43.7 0.12 12.4 0.3 8.8 9 0 0 9 9 9 4 C2H2-type zinc finger FOXP-CC PF16159.5 RLN76850.1 - 3.9e-06 27.4 14.9 0.0043 17.7 0.2 5.6 3 3 3 6 6 6 2 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 RLN76850.1 - 6.6e-06 25.8 39.2 0.051 13.3 2.8 7.9 8 0 0 8 8 8 3 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 RLN76850.1 - 1.1e-05 25.6 19.6 9.9 6.6 0.1 8.2 8 0 0 8 8 8 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 RLN76850.1 - 6e-05 23.3 27.0 0.071 13.4 1.6 5.3 2 2 2 5 5 5 3 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 RLN76850.1 - 0.011 15.9 21.7 0.08 13.1 0.2 5.6 3 2 3 6 6 6 0 Aberrant zinc-finger zf_ZIC PF18366.1 RLN76850.1 - 0.76 9.9 15.1 69 3.7 0.1 6.7 4 4 2 6 6 6 0 Zic proteins zinc finger domain zf-C2H2 PF00096.26 RLN76851.1 - 5.7e-17 61.1 26.8 4e-05 23.8 1.1 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN76851.1 - 2.6e-14 52.7 23.8 0.0016 19.1 0.9 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RLN76851.1 - 3.3e-10 39.9 24.6 7.6e-07 29.3 0.9 5.4 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_aberr PF17017.5 RLN76851.1 - 6.9e-05 23.1 7.9 0.022 14.9 0.7 3.4 1 1 2 3 3 3 2 Aberrant zinc-finger zf-C2H2_8 PF15909.5 RLN76851.1 - 0.0002 21.6 9.8 0.4 11.0 0.1 4.1 1 1 3 4 4 4 2 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 RLN76851.1 - 0.00066 19.4 8.5 0.22 11.3 0.2 3.3 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 RLN76851.1 - 0.00086 19.2 15.3 0.025 14.6 0.3 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RLN76851.1 - 0.0009 19.5 5.8 2.7 8.4 0.2 4.5 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 RLN76851.1 - 0.0024 18.4 7.3 0.028 15.1 0.1 3.2 3 1 1 4 4 3 1 FOXP coiled-coil domain zf_Hakai PF18408.1 RLN76851.1 - 0.0028 17.3 2.5 0.16 11.7 0.0 3.3 3 0 0 3 3 3 1 C2H2 Hakai zinc finger domain zf-H2C2_5 PF13909.6 RLN76851.1 - 0.0069 16.1 14.5 0.62 9.9 1.1 4.6 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_9 PF16293.5 RLN76851.1 - 0.043 13.7 4.4 5.5 6.9 0.0 3.9 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) zf_ZIC PF18366.1 RLN76851.1 - 0.1 12.7 4.6 32 4.7 0.0 4.1 3 1 1 4 4 4 0 Zic proteins zinc finger domain zf-BED PF02892.15 RLN76851.1 - 0.15 12.1 4.4 0.17 11.9 0.6 2.6 2 0 0 2 2 2 0 BED zinc finger zf-met PF12874.7 RLN76851.1 - 0.28 11.6 6.4 32 5.1 0.1 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type CHORD PF04968.12 RLN76851.1 - 0.39 11.5 13.7 13 6.6 0.1 4.2 2 2 2 4 4 4 0 CHORD zf-CGNR PF11706.8 RLN76851.1 - 3.2 7.7 5.9 67 3.5 0.0 3.6 4 0 0 4 4 4 0 CGNR zinc finger Zn-C2H2_12 PF18112.1 RLN76851.1 - 6.3 7.3 12.2 55 4.3 2.0 4.7 5 0 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain DDE_1 PF03184.19 RLN76852.1 - 1.5e-24 86.6 0.2 6.2e-24 84.6 0.1 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.6 RLN76852.1 - 2.5e-14 52.6 0.1 0.0029 17.3 0.0 4.1 3 0 0 3 3 3 3 Homeodomain-like domain CENP-B_N PF04218.13 RLN76852.1 - 1.4e-12 47.0 2.7 0.0042 16.7 0.1 3.6 3 0 0 3 3 3 3 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 RLN76852.1 - 4.5e-12 45.9 4.1 0.0015 18.6 0.0 4.4 4 0 0 4 4 4 3 Helix-turn-helix domain HTH_Tnp_Tc5 PF03221.16 RLN76852.1 - 3.1e-07 30.3 0.0 7.6e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_Tnp_IS630 PF01710.16 RLN76852.1 - 4.5e-06 26.7 0.1 0.35 10.9 0.1 3.4 3 0 0 3 3 3 2 Transposase HTH_50 PF18024.1 RLN76852.1 - 7.6e-06 25.5 0.1 4.7 6.9 0.0 3.9 3 1 0 3 3 3 3 Helix-turn-helix domain HTH_3 PF01381.22 RLN76852.1 - 7.9e-06 25.8 0.1 0.15 12.1 0.0 3.6 3 0 0 3 3 3 1 Helix-turn-helix HTH_29 PF13551.6 RLN76852.1 - 1.9e-05 24.6 0.2 2.4 8.2 0.0 4.0 3 0 0 3 3 3 1 Winged helix-turn helix Sigma70_r4_2 PF08281.12 RLN76852.1 - 4.3e-05 23.1 1.6 2.4 7.9 0.0 4.6 4 0 0 4 4 4 1 Sigma-70, region 4 Cro PF09048.10 RLN76852.1 - 4.8e-05 23.3 4.8 0.31 11.1 0.2 3.6 3 0 0 3 3 3 2 Cro DUF134 PF02001.16 RLN76852.1 - 7.8e-05 23.2 1.9 0.089 13.4 0.1 3.4 3 0 0 3 3 3 1 Protein of unknown function DUF134 MarR_2 PF12802.7 RLN76852.1 - 0.00014 21.7 1.0 2.1 8.3 0.0 4.7 4 0 0 4 4 4 1 MarR family HTH_30 PF13556.6 RLN76852.1 - 0.00041 20.1 4.8 6.9 6.6 0.3 5.8 5 1 1 6 6 6 0 PucR C-terminal helix-turn-helix domain YdaS_antitoxin PF15943.5 RLN76852.1 - 0.00075 19.3 3.6 0.46 10.4 0.0 3.9 4 0 0 4 4 3 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_17 PF12728.7 RLN76852.1 - 0.00094 19.3 0.5 0.37 11.0 0.0 3.4 3 0 0 3 3 3 1 Helix-turn-helix domain BrkDBD PF09607.10 RLN76852.1 - 0.0011 18.6 0.0 3 7.7 0.0 3.8 3 0 0 3 3 3 1 Brinker DNA-binding domain HTH_1 PF00126.27 RLN76852.1 - 0.0013 18.6 13.4 0.023 14.6 0.3 4.2 4 0 0 4 4 3 2 Bacterial regulatory helix-turn-helix protein, lysR family HTH_11 PF08279.12 RLN76852.1 - 0.0017 18.3 0.3 5.4 7.0 0.0 4.1 3 1 0 3 3 3 1 HTH domain Sigma70_r4 PF04545.16 RLN76852.1 - 0.0022 17.4 0.4 4.8 6.8 0.0 4.3 4 0 0 4 4 4 1 Sigma-70, region 4 SabA_adhesion PF18304.1 RLN76852.1 - 0.0053 16.0 2.1 0.18 11.0 0.2 3.0 3 0 0 3 3 3 1 SabA N-terminal extracellular adhesion domain KORA PF16509.5 RLN76852.1 - 0.0055 17.0 2.1 4.4 7.6 0.1 3.3 3 0 0 3 3 2 1 TrfB plasmid transcriptional repressor UPF0122 PF04297.14 RLN76852.1 - 0.027 14.7 1.1 16 5.8 0.1 3.5 2 1 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like SpoIIID PF12116.8 RLN76852.1 - 0.03 14.4 2.1 7.5 6.7 0.5 2.9 2 0 0 2 2 2 0 Stage III sporulation protein D AbiEi_4 PF13338.6 RLN76852.1 - 0.047 13.8 0.7 13 6.1 0.0 3.8 4 0 0 4 4 4 0 Transcriptional regulator, AbiEi antitoxin HTH_Tnp_4 PF13613.6 RLN76852.1 - 0.053 13.3 0.0 16 5.3 0.0 3.5 3 0 0 3 3 3 0 Helix-turn-helix of DDE superfamily endonuclease HTH_psq PF05225.16 RLN76852.1 - 0.059 13.1 0.0 15 5.4 0.0 2.7 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_38 PF13936.6 RLN76852.1 - 0.075 12.8 0.1 24 4.8 0.0 3.6 4 0 0 4 4 3 0 Helix-turn-helix domain HTH_24 PF13412.6 RLN76852.1 - 0.13 11.9 0.0 23 4.6 0.0 3.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Linker_histone PF00538.19 RLN76852.1 - 0.35 11.3 1.5 42 4.6 0.1 3.0 3 0 0 3 3 2 0 linker histone H1 and H5 family HTH_8 PF02954.19 RLN76852.1 - 2.8 7.8 6.6 11 5.9 0.0 3.8 4 0 0 4 4 3 0 Bacterial regulatory protein, Fis family LRR_6 PF13516.6 RLN76853.1 - 5.9e-09 35.3 0.0 0.0028 17.6 0.0 2.9 2 0 0 2 2 2 2 Leucine Rich repeat UQ_con PF00179.26 RLN76854.1 - 2.2e-11 43.6 0.0 6.7e-11 42.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme DNA_topoisoIV PF00521.20 RLN76855.1 - 2.6e-110 369.3 0.0 3.3e-110 368.9 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 RLN76855.1 - 3.5e-42 143.7 0.0 9.3e-42 142.3 0.0 1.8 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 RLN76855.1 - 1.5e-16 60.4 0.0 4.7e-16 58.8 0.0 1.8 2 0 0 2 2 2 1 DNA gyrase B HATPase_c PF02518.26 RLN76855.1 - 1.4e-09 38.4 0.0 4.3e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 RLN76855.1 - 2.5e-07 30.9 0.0 9.5e-07 29.0 0.0 2.0 1 0 0 1 1 1 1 Toprim domain LTD PF00932.19 RLN76856.1 - 2e-07 31.3 0.0 3.2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Lamin Tail Domain Herpes_pp85 PF04637.12 RLN76856.1 - 0.17 10.3 0.0 0.39 9.1 0.0 1.5 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) ABC1 PF03109.16 RLN76857.1 - 4.7e-32 110.6 0.0 8.8e-32 109.8 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Rotamase PF00639.21 RLN76858.1 - 5.4e-20 72.2 0.0 6.3e-20 71.9 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 RLN76858.1 - 5.7e-18 65.6 0.0 5.9e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 RLN76858.1 - 0.00038 21.3 0.0 0.00043 21.1 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain PX PF00787.24 RLN76859.1 - 6e-07 29.4 0.2 9.5e-07 28.8 0.2 1.3 1 0 0 1 1 1 1 PX domain PX PF00787.24 RLN76860.1 - 8.4e-06 25.8 0.4 1.8e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 PX domain DUF1398 PF07166.11 RLN76860.1 - 0.042 13.9 0.1 0.052 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) INCENP_N PF12178.8 RLN76861.1 - 0.075 13.1 0.5 0.075 13.1 0.5 2.0 2 0 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal FH2 PF02181.23 RLN76862.1 - 1.4e-41 142.8 3.5 2e-39 135.8 3.5 2.0 1 1 0 1 1 1 1 Formin Homology 2 Domain CCDC53 PF10152.9 RLN76862.1 - 6.3e-05 23.4 1.1 0.00012 22.5 0.0 2.1 2 1 0 2 2 2 1 Subunit CCDC53 of WASH complex zf-C2H2 PF00096.26 RLN76863.1 - 1.1e-15 57.1 30.9 0.00022 21.5 3.1 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RLN76863.1 - 1.6e-12 47.3 26.3 4.4e-07 30.0 1.7 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 RLN76863.1 - 1.8e-12 47.0 26.6 0.0091 16.8 1.5 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RLN76863.1 - 8.6e-07 28.8 21.2 0.0028 17.6 0.4 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RLN76863.1 - 8.5e-05 22.7 4.6 0.33 11.3 0.1 4.3 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 RLN76863.1 - 0.0051 16.5 13.5 1.2 8.9 0.1 4.5 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 RLN76863.1 - 0.016 15.5 10.0 0.36 11.1 1.3 2.8 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf_Hakai PF18408.1 RLN76863.1 - 0.056 13.2 1.0 0.056 13.2 1.0 2.7 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain zf_ZIC PF18366.1 RLN76863.1 - 0.26 11.4 7.9 7.4 6.8 0.2 3.5 2 1 1 3 3 3 0 Zic proteins zinc finger domain GAGA PF09237.11 RLN76863.1 - 0.34 10.8 4.4 0.41 10.5 1.9 2.3 2 0 0 2 2 2 0 GAGA factor zf-met PF12874.7 RLN76863.1 - 1.2 9.6 11.1 2.7 8.5 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 RLN76863.1 - 2.3 8.3 7.7 4.8 7.3 0.5 3.1 1 1 2 3 3 3 0 Aberrant zinc-finger FOXP-CC PF16159.5 RLN76863.1 - 4.6 7.9 9.1 16 6.2 0.2 3.2 3 1 1 4 4 4 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 RLN76864.1 - 2e-27 94.1 60.2 0.00024 21.4 0.6 8.8 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN76864.1 - 7.3e-24 82.4 52.7 0.00045 20.8 0.5 9.3 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RLN76864.1 - 4.1e-15 55.4 57.7 8.3e-06 26.0 1.0 10.0 10 0 0 10 10 9 7 Zinc-finger double domain zf-C2H2_aberr PF17017.5 RLN76864.1 - 2.5e-06 27.8 21.8 0.087 13.0 0.7 6.2 2 2 4 6 6 6 2 Aberrant zinc-finger FOXP-CC PF16159.5 RLN76864.1 - 3.7e-05 24.3 22.3 0.017 15.7 0.1 5.6 6 2 0 6 6 6 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 RLN76864.1 - 6.6e-05 23.1 28.7 0.79 10.1 0.7 5.5 2 2 4 6 6 6 5 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 RLN76864.1 - 0.00036 20.2 33.0 0.29 10.9 0.3 8.3 8 0 0 8 8 8 3 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 RLN76864.1 - 0.002 18.4 29.7 13 6.2 0.0 8.9 9 0 0 9 9 9 1 Zinc-finger double-stranded RNA-binding zf_ZIC PF18366.1 RLN76864.1 - 0.0047 17.0 11.6 5.7 7.1 0.1 6.4 5 1 1 6 6 6 1 Zic proteins zinc finger domain zf-C2H2_11 PF16622.5 RLN76864.1 - 0.0059 16.3 37.2 0.95 9.3 0.1 7.8 8 0 0 8 8 8 3 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 RLN76864.1 - 0.0082 16.1 1.2 0.0082 16.1 1.2 8.4 9 0 0 9 9 9 2 C2H2-type zinc finger TPMT PF05724.11 RLN76864.1 - 0.095 12.3 0.1 17 5.0 0.0 2.3 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) CHORD PF04968.12 RLN76864.1 - 7.6 7.3 34.8 26 5.6 0.9 7.6 4 4 4 8 8 8 0 CHORD Pex16 PF08610.10 RLN76865.1 - 2e-29 102.8 0.5 4.4e-12 45.8 0.0 3.2 2 1 1 3 3 3 3 Peroxisomal membrane protein (Pex16) UCH PF00443.29 RLN76868.1 - 6.5e-31 107.7 0.0 1.2e-30 106.9 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN76868.1 - 2.6e-09 37.1 0.1 9.4e-08 32.0 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase FKBP_C PF00254.28 RLN76869.1 - 3.3e-21 75.4 0.0 4.1e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase V-set PF07686.17 RLN76869.1 - 0.013 15.7 0.0 0.6 10.3 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin V-set domain FKBP_N_2 PF18023.1 RLN76869.1 - 0.18 11.9 0.0 0.22 11.7 0.0 1.4 1 1 0 1 1 1 0 BDBT FKBP like N-terminal zf-C2H2 PF00096.26 RLN76870.1 - 2.8e-13 49.5 34.5 0.00042 20.6 2.0 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RLN76870.1 - 3.2e-12 46.3 31.5 1.2e-06 28.7 2.2 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 RLN76870.1 - 1.2e-11 44.4 30.3 0.0032 18.2 5.5 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RLN76870.1 - 0.00015 21.9 6.3 3.7 7.9 0.1 4.4 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 RLN76870.1 - 0.0056 16.9 9.2 0.62 10.4 1.3 3.0 1 1 2 3 3 3 3 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 RLN76870.1 - 0.019 15.0 24.6 0.12 12.4 3.5 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf_Hakai PF18408.1 RLN76870.1 - 0.13 12.0 0.3 0.13 12.0 0.3 2.8 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain zf_ZIC PF18366.1 RLN76870.1 - 0.29 11.3 9.6 1.3 9.2 0.2 3.4 2 1 1 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_aberr PF17017.5 RLN76870.1 - 0.64 10.1 10.6 5.8 7.0 0.1 3.6 1 1 3 4 4 4 0 Aberrant zinc-finger CHORD PF04968.12 RLN76870.1 - 0.96 10.2 16.8 2.9 8.7 0.4 4.0 2 2 2 4 4 4 0 CHORD zf-H2C2_5 PF13909.6 RLN76870.1 - 1.1 9.1 14.9 2 8.2 1.3 4.3 4 0 0 4 4 4 0 C2H2-type zinc-finger domain LRR_6 PF13516.6 RLN76871.1 - 1.4e-13 49.7 25.5 0.00054 19.8 0.2 7.5 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 RLN76871.1 - 2.8e-07 30.8 19.4 0.0021 18.5 0.3 5.2 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN76871.1 - 0.32 10.8 25.5 3.8 7.4 0.1 5.7 3 2 2 5 5 5 0 Leucine rich repeat Porin_5 PF16930.5 RLN76872.1 - 0.1 11.1 0.1 0.13 10.7 0.1 1.1 1 0 0 1 1 1 0 Putative porin DUF4148 PF13663.6 RLN76872.1 - 0.41 10.8 3.4 0.85 9.9 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) PQQ PF01011.21 RLN76911.1 - 2e-06 27.4 1.2 8.9e-06 25.4 0.1 2.6 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_3 PF13570.6 RLN76911.1 - 0.011 16.2 2.7 3.8 8.1 0.7 4.6 4 0 0 4 4 4 0 PQQ-like domain PQQ_2 PF13360.6 RLN76911.1 - 0.022 14.3 6.9 0.086 12.4 0.7 3.1 3 2 0 3 3 3 0 PQQ-like domain TAXi_C PF14541.6 RLN76931.1 - 0.02 14.7 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Ca_hom_mod PF14798.6 RLN76931.1 - 0.024 13.7 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Calcium homeostasis modulator Myosin_head PF00063.21 RLN76933.1 - 1.7e-193 644.6 2.1 2e-193 644.4 2.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) CbiA PF01656.23 RLN76933.1 - 0.0027 17.8 0.0 0.0073 16.4 0.0 1.8 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 RLN76933.1 - 0.0089 16.4 0.0 0.031 14.7 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 RLN76933.1 - 0.0092 16.3 0.1 0.048 14.0 0.1 2.3 2 1 0 2 2 2 1 AAA domain Hpr_kinase_C PF07475.12 RLN76933.1 - 0.0094 15.5 0.0 4.4 6.8 0.0 2.4 2 0 0 2 2 2 2 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 RLN76933.1 - 0.024 14.9 0.1 0.25 11.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 RLN76933.1 - 0.031 13.3 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 RLN76933.1 - 0.033 14.6 0.1 0.55 10.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 RLN76933.1 - 0.051 13.1 0.0 6.8 6.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_6 PF12774.7 RLN76933.1 - 0.068 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region TUDOR_5 PF18359.1 RLN76935.1 - 8.3e-13 47.8 3.5 2e-07 30.6 0.5 3.2 3 0 0 3 3 3 2 Histone methyltransferase Tudor domain 1 Tudor_3 PF18115.1 RLN76935.1 - 1.2e-05 25.1 0.1 0.0013 18.5 0.0 2.7 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 RLN76935.1 - 0.00012 22.5 0.4 0.18 12.3 0.0 2.9 3 0 0 3 3 3 2 Agenet domain Tudor_2 PF18104.1 RLN76935.1 - 0.00078 19.1 0.4 4.6 7.0 0.1 3.5 3 0 0 3 3 3 2 Jumonji domain-containing protein 2A Tudor domain DUF4537 PF15057.6 RLN76935.1 - 0.002 18.2 0.0 0.22 11.6 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 RLN76935.1 - 0.038 13.8 0.3 1 9.2 0.1 2.5 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain 53-BP1_Tudor PF09038.10 RLN76935.1 - 0.074 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor FDF PF09532.10 RLN76935.1 - 0.12 13.3 0.7 0.19 12.7 0.7 1.2 1 0 0 1 1 1 0 FDF domain GrpE PF01025.19 RLN76936.1 - 0.27 10.9 3.5 0.5 10.0 1.2 2.6 2 0 0 2 2 2 0 GrpE EMP70 PF02990.16 RLN76937.1 - 5.8e-200 665.4 1.7 6.9e-200 665.1 1.7 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 Tubulin_3 PF14881.6 RLN76938.1 - 2.5e-07 30.6 0.0 5.1e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain EF-hand_1 PF00036.32 RLN77040.1 - 1.4e-40 133.8 8.2 2.2e-07 29.9 0.0 7.4 7 0 0 7 7 7 6 EF hand EF-hand_6 PF13405.6 RLN77040.1 - 9.7e-35 115.5 8.5 5.8e-06 25.8 0.0 7.4 7 0 0 7 7 7 6 EF-hand domain EF-hand_7 PF13499.6 RLN77040.1 - 1.7e-32 111.7 7.7 5.1e-13 49.3 0.0 4.7 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 RLN77040.1 - 1.5e-27 93.8 15.5 2.9e-05 23.4 0.3 7.6 8 0 0 8 8 8 6 EF hand EF-hand_8 PF13833.6 RLN77040.1 - 1.7e-19 69.4 18.4 0.0023 17.8 0.0 7.0 5 2 2 7 7 7 5 EF-hand domain pair EF-hand_4 PF12763.7 RLN77040.1 - 5.3e-07 29.5 7.7 0.066 13.2 0.1 5.6 2 2 3 5 5 5 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RLN77040.1 - 0.00024 21.4 0.6 16 5.8 0.0 4.5 3 1 1 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 RLN77040.1 - 0.00057 20.0 0.0 16 5.8 0.0 4.4 4 0 0 4 4 4 0 Dockerin type I domain EF-hand_2 PF09068.11 RLN77040.1 - 0.016 15.4 0.0 1.3 9.2 0.0 3.3 3 1 0 3 3 3 0 EF hand FG-GAP PF01839.23 RLN77040.1 - 0.031 14.4 7.4 14 6.0 0.1 4.6 4 0 0 4 4 4 0 FG-GAP repeat EF-hand_9 PF14658.6 RLN77040.1 - 0.054 13.8 0.2 53 4.2 0.0 4.0 3 1 1 4 4 4 0 EF-hand domain EF-hand_10 PF14788.6 RLN77040.1 - 0.065 13.1 1.7 14 5.6 0.1 4.1 4 0 0 4 4 4 0 EF hand EamA PF00892.20 RLN77041.1 - 3.1e-22 79.2 36.7 2.7e-11 43.8 2.3 3.3 3 0 0 3 3 3 3 EamA-like transporter family SLC35F PF06027.12 RLN77041.1 - 1.2e-12 48.0 19.1 3.9e-12 46.3 17.6 2.3 2 1 1 3 3 3 2 Solute carrier family 35 TPT PF03151.16 RLN77041.1 - 7.5e-07 28.8 10.0 1.8e-06 27.5 10.0 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family PUNUT PF16913.5 RLN77041.1 - 3.6e-06 26.4 18.3 1.2e-05 24.7 6.2 3.0 2 1 1 3 3 3 2 Purine nucleobase transmembrane transport Sugar_transport PF06800.12 RLN77041.1 - 0.0019 17.6 0.4 0.0019 17.6 0.4 3.3 3 1 0 3 3 3 1 Sugar transport protein DUF2651 PF10852.8 RLN77041.1 - 0.024 15.2 1.0 0.024 15.2 1.0 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF2651) CcmD PF04995.14 RLN77041.1 - 0.04 14.0 0.1 0.04 14.0 0.1 2.8 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) PQ-loop PF04193.14 RLN77042.1 - 1e-09 38.0 0.8 1.3e-09 37.6 0.8 1.2 1 0 0 1 1 1 1 PQ loop repeat MtN3_slv PF03083.16 RLN77042.1 - 0.0083 16.1 0.7 0.0091 16.0 0.7 1.1 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange RIO1 PF01163.22 RLN77043.1 - 7.7e-58 195.2 0.1 1.6e-57 194.1 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 RLN77043.1 - 4.2e-07 30.1 0.0 0.00015 21.7 0.1 2.7 2 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 RLN77043.1 - 1.8e-06 27.5 2.3 6.9e-06 25.6 2.3 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family OrfB_Zn_ribbon PF07282.11 RLN77043.1 - 7.4e-06 25.8 3.2 0.061 13.3 0.2 3.1 3 0 0 3 3 3 2 Putative transposase DNA-binding domain Pkinase_fungal PF17667.1 RLN77043.1 - 1e-05 24.5 0.0 2.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 RLN77043.1 - 0.00092 18.7 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 RLN77043.1 - 0.034 13.7 0.0 0.07 12.7 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 RLN77043.1 - 0.037 13.3 0.0 0.087 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein tyrosine kinase DUF5575 PF17738.1 RLN77044.1 - 0.026 13.6 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5575) Casc1_N PF15927.5 RLN77045.1 - 8.1e-30 104.0 35.6 3.2e-28 98.8 35.6 2.9 1 1 0 1 1 1 1 Cancer susceptibility candidate 1 N-terminus PAPS_reduct PF01507.19 RLN77046.1 - 9.2e-44 149.5 0.0 1.3e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Glutaredoxin PF00462.24 RLN77046.1 - 7.4e-13 48.5 0.4 2.1e-12 47.1 0.1 1.9 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_2 PF13098.6 RLN77046.1 - 0.089 13.3 0.6 0.78 10.2 0.6 2.4 1 1 0 1 1 1 0 Thioredoxin-like domain DUF1380 PF07128.12 RLN77046.1 - 0.09 13.0 0.0 0.41 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1380) ANAPC4_WD40 PF12894.7 RLN77047.1 - 6.7e-06 26.3 0.1 0.075 13.3 0.0 3.1 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RLN77047.1 - 0.0013 19.5 1.2 8.8 7.4 0.0 4.9 4 0 0 4 4 4 1 WD domain, G-beta repeat EF-hand_7 PF13499.6 RLN77047.1 - 0.003 18.0 0.2 0.01 16.3 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN77047.1 - 0.036 13.6 0.1 0.036 13.6 0.1 2.1 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.6 RLN77047.1 - 0.07 13.1 0.0 0.26 11.3 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain PA26 PF04636.13 RLN77048.1 - 5.2e-121 404.6 0.0 6.8e-121 404.2 0.0 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) SDA1 PF05285.12 RLN77048.1 - 6.3 6.1 15.9 10 5.4 15.9 1.2 1 0 0 1 1 1 0 SDA1 KH_2 PF07650.17 RLN77057.1 - 8.1e-06 25.6 0.1 9.9e-06 25.3 0.1 1.1 1 0 0 1 1 1 1 KH domain Mus7 PF09462.10 RLN77071.1 - 0.0035 16.3 0.4 0.005 15.8 0.4 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family IBR PF01485.21 RLN77091.1 - 5.3e-24 84.2 24.8 2e-16 59.9 3.8 2.4 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 RLN77091.1 - 0.011 15.8 2.7 0.011 15.8 2.7 3.7 2 2 2 4 4 4 0 AN1-like Zinc finger Pkinase_Tyr PF07714.17 RLN77113.1 - 1.2e-53 182.1 0.0 4.8e-40 137.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN77113.1 - 3.3e-47 161.1 0.0 1.1e-34 120.0 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Ank_4 PF13637.6 RLN77113.1 - 2.2e-38 130.1 2.2 2.3e-08 34.4 0.0 5.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN77113.1 - 5.2e-36 123.1 3.3 2.8e-17 63.1 0.2 4.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 RLN77113.1 - 1.3e-24 85.5 4.3 0.0022 18.4 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 RLN77113.1 - 7.5e-24 83.5 2.0 1.6e-06 28.3 0.1 5.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN77113.1 - 1e-22 77.7 0.2 0.014 15.9 0.0 7.1 6 0 0 6 6 6 5 Ankyrin repeat Arm PF00514.23 RLN77113.1 - 5.1e-18 64.5 6.0 0.0013 18.7 0.0 7.2 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN77113.1 - 3.8e-06 27.3 6.5 0.0012 19.3 0.2 4.2 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.22 RLN77113.1 - 0.0007 19.6 2.8 2.8 8.4 0.0 5.4 7 0 0 7 7 4 1 HEAT repeat HEAT_2 PF13646.6 RLN77113.1 - 0.0034 17.7 23.3 0.093 13.1 5.3 5.6 4 2 2 7 7 6 3 HEAT repeats BRX PF08381.11 RLN77113.1 - 0.035 13.5 1.5 0.27 10.6 0.1 2.4 2 0 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 Kinase-like PF14531.6 RLN77113.1 - 0.044 13.1 0.0 1.4 8.2 0.0 2.6 2 0 0 2 2 2 0 Kinase-like HEAT_PBS PF03130.16 RLN77113.1 - 2.3 9.2 15.3 26 5.9 0.2 6.6 6 0 0 6 6 5 0 PBS lyase HEAT-like repeat zf-C2H2 PF00096.26 RLN77114.1 - 6.9e-19 67.2 22.2 5.6e-07 29.7 0.8 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN77114.1 - 4.9e-14 51.8 20.2 0.0011 19.6 0.6 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RLN77114.1 - 1.5e-09 37.9 27.4 3.6e-06 27.1 2.1 5.5 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 RLN77114.1 - 0.011 15.7 0.3 0.011 15.7 0.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RLN77114.1 - 0.017 14.9 12.8 0.11 12.3 0.2 3.3 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 RLN77114.1 - 0.021 15.0 4.5 2 8.6 1.0 3.2 1 1 2 3 3 3 0 Aberrant zinc-finger zf-C2HC_2 PF13913.6 RLN77114.1 - 0.029 14.3 1.3 1.4 8.9 0.0 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 RLN77114.1 - 0.041 13.6 0.2 0.041 13.6 0.2 4.3 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 RLN77114.1 - 0.063 13.6 6.6 0.8 10.1 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 RLN77114.1 - 0.067 13.5 8.2 2.2 8.7 0.4 3.2 1 1 2 3 3 3 0 C2H2-type zinc ribbon GAGA PF09237.11 RLN77114.1 - 0.43 10.4 5.5 0.32 10.8 0.6 2.8 2 1 1 3 3 3 0 GAGA factor FOXP-CC PF16159.5 RLN77114.1 - 0.63 10.7 6.9 1.2 9.9 0.2 3.2 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-Nse PF11789.8 RLN77114.1 - 1.7 8.5 5.9 4.6 7.1 0.0 2.6 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Glycos_transf_1 PF00534.20 RLN77129.1 - 1.1e-06 28.4 0.0 4.3e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RLN77129.1 - 0.00046 20.6 0.0 0.00072 20.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 RLN77129.1 - 0.042 14.2 0.1 0.13 12.7 0.1 1.8 1 1 0 1 1 1 0 Glycosyl transferases group 1 POTRA_3 PF17287.2 RLN77129.1 - 0.16 11.4 0.3 0.33 10.5 0.3 1.4 1 0 0 1 1 1 0 POTRA domain RhoGAP PF00620.27 RLN77130.1 - 6e-15 55.4 0.0 1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PBD PF00786.28 RLN77130.1 - 3.6e-06 27.2 0.0 7.6e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain Abhydrolase_1 PF00561.20 RLN77131.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Uma2 PF05685.12 RLN77131.1 - 0.068 12.7 0.1 0.16 11.5 0.1 1.6 1 0 0 1 1 1 0 Putative restriction endonuclease Hydrolase_4 PF12146.8 RLN77131.1 - 0.17 11.2 0.0 0.39 10.0 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 zf-CGNR PF11706.8 RLN77157.1 - 9.8 6.1 17.7 1.9 8.4 0.5 3.9 3 1 1 4 4 4 0 CGNR zinc finger NmrA PF05368.13 RLN77158.1 - 2.1e-15 57.0 0.0 2.1e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 RLN77158.1 - 2.1e-13 50.5 0.0 3e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Glu_syn_central PF04898.14 RLN77158.1 - 0.022 14.2 0.0 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 Glutamate synthase central domain AP_endonuc_2 PF01261.24 RLN77158.1 - 0.049 13.1 0.0 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel KR PF08659.10 RLN77158.1 - 0.075 12.9 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 KR domain AhpC-TSA PF00578.21 RLN77158.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Clat_adaptor_s PF01217.20 RLN77159.1 - 1.4e-08 34.8 0.1 1.7e-08 34.5 0.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Herpes_ori_bp PF02399.15 RLN77159.1 - 0.096 10.7 0.3 0.12 10.4 0.3 1.1 1 0 0 1 1 1 0 Origin of replication binding protein WD40 PF00400.32 RLN77160.1 - 7.6e-14 51.9 8.1 0.00014 22.5 0.6 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN77160.1 - 3.9e-13 49.5 0.0 0.00013 22.2 0.0 5.1 4 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN77160.1 - 0.00036 19.6 0.4 0.0025 16.9 0.0 2.5 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RLN77160.1 - 0.0044 15.7 0.1 0.07 11.8 0.0 2.5 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 RLN77160.1 - 0.041 13.6 0.1 0.096 12.4 0.1 1.7 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature DUF2807 PF10988.8 RLN77161.1 - 3.1e-23 82.5 36.8 8.3e-15 55.0 7.1 5.8 3 2 1 4 4 4 3 Putative auto-transporter adhesin, head GIN domain DUF4140 PF13600.6 RLN77161.1 - 0.16 12.4 1.0 1.4 9.4 0.0 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Pkinase_Tyr PF07714.17 RLN77164.1 - 9e-54 182.5 0.0 1.1e-41 142.8 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 RLN77164.1 - 1.4e-48 165.6 0.0 6.2e-38 130.7 0.0 3.4 3 0 0 3 3 3 2 Protein kinase domain Kinase-like PF14531.6 RLN77164.1 - 0.0052 16.1 0.0 0.8 9.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 RLN77164.1 - 0.037 12.8 0.0 0.059 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 RLN77164.1 - 0.067 12.5 0.0 1.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RLN77164.1 - 0.2 11.2 0.1 1.5 8.4 0.0 2.3 3 0 0 3 3 3 0 RIO1 family NmrA PF05368.13 RLN77165.1 - 3.7e-17 62.7 0.0 4.9e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 RLN77165.1 - 1.1e-13 51.5 0.0 1.8e-13 50.8 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 RLN77165.1 - 0.0038 17.2 0.0 0.0067 16.4 0.0 1.4 1 0 0 1 1 1 1 KR domain AhpC-TSA PF00578.21 RLN77165.1 - 0.049 13.5 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family PTH2 PF01981.16 RLN77165.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 Ish1 PF10281.9 RLN77165.1 - 0.18 12.1 0.4 0.5 10.7 0.4 1.8 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein DUF2807 PF10988.8 RLN77167.1 - 3.3e-10 40.0 13.2 1.1e-08 35.1 13.1 2.6 1 1 0 1 1 1 1 Putative auto-transporter adhesin, head GIN domain DUF563 PF04577.14 RLN77168.1 - 3.6e-25 89.4 0.0 5.9e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Pkinase_Tyr PF07714.17 RLN77267.1 - 8.2e-36 123.6 0.0 1.2e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN77267.1 - 1.2e-29 103.4 0.0 2.2e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 RLN77267.1 - 0.087 12.7 2.6 0.23 11.3 2.4 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Arm PF00514.23 RLN77268.1 - 1.5e-29 101.1 17.8 8.8e-07 28.8 0.1 8.7 8 1 1 9 9 9 6 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 RLN77268.1 - 3e-08 33.6 0.5 0.012 15.6 0.0 3.4 2 1 1 3 3 3 3 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 RLN77268.1 - 1.8e-07 30.9 0.3 0.061 12.8 0.0 3.6 1 1 2 3 3 3 3 Armadillo-like HEAT PF02985.22 RLN77268.1 - 1.2e-06 28.2 5.4 10 6.7 0.0 7.0 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 RLN77268.1 - 0.00019 21.9 21.6 0.056 14.0 2.3 5.4 3 3 3 6 6 6 3 HEAT-like repeat Acyl-CoA_dh_N PF02771.16 RLN77268.1 - 0.00024 21.7 2.5 17 6.1 0.0 5.8 5 2 1 6 6 6 1 Acyl-CoA dehydrogenase, N-terminal domain HEAT_2 PF13646.6 RLN77268.1 - 0.00052 20.4 21.7 0.0074 16.7 2.8 4.6 1 1 5 6 6 6 3 HEAT repeats IFRD PF05004.13 RLN77268.1 - 0.014 14.5 1.5 0.39 9.8 0.1 2.5 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) PLN_propep PF16485.5 RLN77268.1 - 0.044 13.5 0.0 5.6 6.8 0.0 3.8 4 0 0 4 4 4 0 Protealysin propeptide HEAT_PBS PF03130.16 RLN77268.1 - 5.9 7.9 23.3 12 6.9 0.3 7.5 7 2 0 7 7 7 0 PBS lyase HEAT-like repeat MIG-14_Wnt-bd PF06664.12 RLN77269.1 - 2.6e-05 23.6 4.9 2.6e-05 23.6 4.9 2.0 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion NPP1 PF05630.11 RLN77271.1 - 2.2e-28 99.8 0.6 3.1e-28 99.2 0.6 1.2 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Metallophos PF00149.28 RLN77272.1 - 1.1e-13 52.2 0.8 1.7e-13 51.6 0.8 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L23eN PF03939.13 RLN77273.1 - 5.1e-17 61.8 5.5 1.1e-16 60.7 5.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 RLN77273.1 - 2.6e-16 59.7 1.3 2.6e-16 59.7 1.3 2.3 2 2 0 2 2 2 1 Ribosomal protein L23 YihI PF04220.12 RLN77273.1 - 0.02 14.6 0.3 0.027 14.2 0.2 1.4 1 1 0 1 1 1 0 Der GTPase activator (YihI) Metallophos PF00149.28 RLN77274.1 - 1.3e-12 48.6 0.4 2.2e-12 47.9 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase VPS13_mid_rpt PF16910.5 RLN77275.1 - 1.5e-44 152.2 0.0 3.6e-37 128.1 0.0 4.9 4 1 0 4 4 4 3 Repeating coiled region of VPS13 VPS13 PF16908.5 RLN77275.1 - 3.6e-44 151.3 4.7 3.2e-43 148.2 2.0 3.3 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 RLN77275.1 - 3.3e-37 128.3 0.0 2.7e-30 105.7 0.0 4.1 4 0 0 4 4 4 3 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 RLN77275.1 - 1e-23 84.0 0.0 1.9e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 RLN77275.1 - 5.5e-23 81.3 0.0 2.1e-22 79.4 0.0 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 DUF2196 PF09962.9 RLN77275.1 - 0.049 13.6 0.0 0.23 11.4 0.0 2.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2196) Apt1 PF10351.9 RLN77275.1 - 0.051 12.4 3.1 0.11 11.3 0.0 2.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain Striatin PF08232.12 RLN77276.1 - 8.4e-18 65.4 2.2 1.1e-17 65.1 2.2 1.1 1 0 0 1 1 1 1 Striatin family WD40 PF00400.32 RLN77276.1 - 0.0023 18.7 0.2 0.27 12.2 0.2 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF3450 PF11932.8 RLN77276.1 - 0.0024 17.2 3.0 0.0034 16.7 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) PTH2 PF01981.16 RLN77277.1 - 5.8e-46 155.6 0.5 8.1e-46 155.1 0.5 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 TPR_14 PF13428.6 RLN77277.1 - 0.0055 17.4 0.2 0.023 15.5 0.2 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN77277.1 - 0.008 16.8 0.1 0.022 15.4 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat HTH_ParB PF17762.1 RLN77277.1 - 0.03 14.1 0.1 0.067 13.0 0.1 1.5 1 0 0 1 1 1 0 HTH domain found in ParB protein TPR_11 PF13414.6 RLN77277.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 TPR repeat Metallophos PF00149.28 RLN77278.1 - 3.7e-08 34.1 0.8 5.5e-08 33.6 0.3 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase tRNA-synt_1d PF00750.19 RLN77296.1 - 9.7e-63 212.2 0.0 1.4e-62 211.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 RLN77296.1 - 3.1e-27 95.1 0.2 2.5e-26 92.2 0.0 2.5 3 0 0 3 3 3 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 RLN77296.1 - 3.9e-06 27.4 0.0 5.4e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1 PF00133.22 RLN77296.1 - 0.025 12.8 0.0 0.44 8.7 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 RLN77296.1 - 0.087 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain PHD PF00628.29 RLN77297.1 - 0.49 10.3 36.2 0.09 12.7 5.1 4.6 4 1 0 4 4 4 0 PHD-finger Sugar_tr PF00083.24 RLN77298.1 - 2.3e-49 168.5 4.0 3.8e-49 167.8 4.0 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN77298.1 - 7.7e-10 38.2 9.1 7.7e-10 38.2 9.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Uma2 PF05685.12 RLN77313.1 - 0.0038 16.8 0.0 0.0054 16.3 0.0 1.2 1 0 0 1 1 1 1 Putative restriction endonuclease Peptidase_M13_N PF05649.13 RLN77313.1 - 0.14 11.8 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M13 GDA1_CD39 PF01150.17 RLN77314.1 - 9.7e-09 34.4 0.0 1.4e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Tagatose_6_P_K PF08013.11 RLN77314.1 - 0.13 10.9 0.1 2.5 6.7 0.1 2.1 2 0 0 2 2 2 0 Tagatose 6 phosphate kinase Acetyltransf_16 PF05301.11 RLN77326.1 - 2.3e-36 125.2 0.0 2.8e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_10 PF13673.7 RLN77326.1 - 0.0026 17.7 0.0 0.036 14.0 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RLN77326.1 - 0.0048 17.1 0.0 0.0065 16.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RLN77326.1 - 0.0098 16.3 0.0 0.023 15.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain RRM_1 PF00076.22 RLN77327.1 - 1.5e-06 28.0 0.0 2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 RLN77327.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Limkain b1 UBM PF14377.6 RLN77327.1 - 0.26 10.8 2.7 0.53 9.8 2.7 1.6 1 0 0 1 1 1 0 Ubiquitin binding region Ank_4 PF13637.6 RLN77328.1 - 1.7e-14 54.0 2.2 4e-06 27.3 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN77328.1 - 3.8e-13 48.3 1.5 0.078 13.6 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.7 RLN77328.1 - 6.2e-13 49.1 1.1 2.2e-05 25.0 0.1 3.6 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Aida_C2 PF14186.6 RLN77328.1 - 3e-12 46.4 0.0 1.7e-07 31.0 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal adhesion Ank_5 PF13857.6 RLN77328.1 - 5.8e-11 42.4 1.0 0.0027 18.0 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PH PF00169.29 RLN77328.1 - 2.6e-06 27.9 0.0 7.8e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 PH domain Ank PF00023.30 RLN77328.1 - 4e-06 27.0 1.5 0.15 12.6 0.0 3.9 3 1 0 3 3 3 2 Ankyrin repeat IQ PF00612.27 RLN77328.1 - 0.19 11.6 0.1 0.062 13.1 2.3 11.6 13 1 0 13 13 13 0 IQ calmodulin-binding motif zf-RING_11 PF17123.5 RLN77330.1 - 7.7e-11 41.5 1.9 7.7e-11 41.5 1.9 2.5 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_2 PF13639.6 RLN77330.1 - 1.6e-10 41.1 3.9 1.6e-10 41.1 3.9 4.2 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN77330.1 - 1.5e-07 31.1 3.3 1.5e-07 31.1 3.3 5.2 5 2 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN77330.1 - 5.4e-07 29.4 3.2 5.4e-07 29.4 3.2 4.8 3 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN77330.1 - 9.2e-06 25.5 3.6 9.2e-06 25.5 3.6 4.4 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RLN77330.1 - 1.3e-05 25.0 2.0 1.3e-05 25.0 2.0 4.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN77330.1 - 2.5e-05 24.5 1.8 2.5e-05 24.5 1.8 3.5 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 RLN77330.1 - 0.00044 20.3 0.6 0.00044 20.3 0.6 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 RLN77330.1 - 0.0011 19.0 0.3 0.0011 19.0 0.3 4.5 4 2 0 4 4 4 1 RING-type zinc-finger PHD PF00628.29 RLN77330.1 - 0.01 15.7 1.7 0.01 15.7 1.7 4.2 4 2 0 4 4 4 0 PHD-finger zf-C3HC4_4 PF15227.6 RLN77330.1 - 0.01 16.0 2.4 0.01 16.0 2.4 4.7 4 2 0 4 4 4 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 RLN77330.1 - 0.011 15.5 2.7 0.011 15.5 2.7 3.9 4 1 0 4 4 4 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 RLN77330.1 - 0.017 14.7 2.4 0.017 14.7 2.4 3.2 4 1 0 4 4 3 0 Zinc-ribbon, C4HC2 type Chorion_2 PF03964.15 RLN77330.1 - 0.042 14.7 0.6 0.62 10.9 0.0 2.2 2 0 0 2 2 2 0 Chorion family 2 zinc-ribbons_6 PF07191.12 RLN77330.1 - 0.082 12.9 20.8 0.083 12.9 3.9 3.7 3 1 1 4 4 4 0 zinc-ribbons DZR PF12773.7 RLN77330.1 - 3.5 7.7 30.3 2.1 8.4 0.5 3.8 2 1 0 2 2 1 0 Double zinc ribbon YacG PF03884.14 RLN77330.1 - 4 7.2 15.1 17 5.2 2.7 3.7 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG Nop14 PF04147.12 RLN77364.1 - 1.8e-05 23.2 13.7 2.2e-05 22.9 13.7 1.2 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 RLN77364.1 - 0.00056 19.4 19.4 0.00075 19.0 19.4 1.2 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 RLN77364.1 - 0.087 12.2 25.2 0.16 11.3 25.2 1.4 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 RLN77364.1 - 0.16 11.3 25.1 0.27 10.5 25.1 1.5 1 0 0 1 1 1 0 NOA36 protein DUF4746 PF15928.5 RLN77364.1 - 0.68 9.3 8.0 1 8.7 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SAPS PF04499.15 RLN77364.1 - 1.6 7.4 10.1 2 7.1 10.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Raftlin PF15250.6 RLN77364.1 - 2 7.1 5.7 2.7 6.7 5.7 1.1 1 0 0 1 1 1 0 Raftlin COPI_C PF06957.11 RLN77364.1 - 2.1 7.0 13.8 3.2 6.4 13.8 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus CDC45 PF02724.14 RLN77364.1 - 6.9 4.8 21.1 13 3.9 21.1 1.4 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_28 PF00295.17 RLN77380.1 - 7.9e-09 35.0 1.7 8e-09 35.0 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Ank_2 PF12796.7 RLN77406.1 - 2.2e-27 95.5 1.0 1.7e-07 31.7 0.0 6.0 3 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN77406.1 - 2.9e-26 91.5 0.4 4.3e-05 24.0 0.0 6.9 3 3 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN77406.1 - 2.2e-20 72.4 4.0 2.5e-06 27.7 0.0 5.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN77406.1 - 2.2e-14 52.1 2.4 0.025 15.1 0.1 7.5 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 RLN77406.1 - 7e-12 45.2 2.2 0.0018 18.6 0.1 5.4 4 0 0 4 4 4 2 Ankyrin repeat Fic PF02661.18 RLN77406.1 - 8.4e-11 42.6 0.0 2.5e-10 41.1 0.0 1.9 1 0 0 1 1 1 1 Fic/DOC family bHLH-MYC_N PF14215.6 RLN77406.1 - 4.2e-05 23.9 0.1 9.2e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal Glutaredoxin PF00462.24 RLN77407.1 - 2.3e-05 24.5 0.2 3.3e-05 24.0 0.2 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 RLN77407.1 - 7.8e-05 23.0 0.0 8.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN77407.1 - 0.0056 17.0 0.0 0.006 16.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain CH PF00307.31 RLN77408.1 - 9.1e-07 29.0 0.1 1.9e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain EB1 PF03271.17 RLN77408.1 - 0.00011 22.4 0.0 0.00024 21.3 0.0 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH_2 PF06294.11 RLN77408.1 - 0.0018 18.4 0.0 0.011 15.8 0.0 2.1 2 0 0 2 2 2 1 CH-like domain in sperm protein Ank_2 PF12796.7 RLN77423.1 - 2.4e-55 185.1 19.1 2.7e-09 37.5 0.1 6.1 2 1 8 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN77423.1 - 9e-41 137.7 7.1 1e-07 32.3 0.0 7.9 7 1 1 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN77423.1 - 1.7e-39 133.4 17.6 6.7e-05 23.1 0.0 12.9 5 1 8 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN77423.1 - 3.6e-25 85.3 4.1 0.57 10.9 0.1 12.5 9 3 3 12 12 12 5 Ankyrin repeat DUF5049 PF16468.5 RLN77423.1 - 6.8e-08 32.3 0.0 2.6 8.0 0.0 7.6 5 2 3 8 8 8 1 Domain of unknown function (DUF5049) Ank PF00023.30 RLN77423.1 - 9.1e-07 29.1 0.2 24 5.6 0.0 8.4 2 1 3 5 5 5 0 Ankyrin repeat CNOT1_HEAT PF16418.5 RLN77423.1 - 0.036 14.1 0.4 62 3.6 0.0 4.9 4 2 3 7 7 7 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Helicase_PWI PF18149.1 RLN77423.1 - 0.041 14.1 0.0 1.1 9.4 0.0 3.0 3 1 0 3 3 3 0 N-terminal helicase PWI domain Chlorophyllase PF07224.11 RLN77423.1 - 0.095 11.7 0.4 10 5.0 0.0 2.7 1 1 2 3 3 3 0 Chlorophyllase DUF4514 PF14986.6 RLN77512.1 - 0.012 15.6 0.3 0.028 14.4 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) TMEM154 PF15102.6 RLN77512.1 - 0.027 14.4 1.3 0.1 12.5 1.2 2.0 1 1 0 1 1 1 0 TMEM154 protein family EI24 PF07264.11 RLN77513.1 - 9.5e-47 159.5 31.7 8.2e-25 88.1 14.4 2.1 2 0 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) DUF996 PF06195.13 RLN77513.1 - 0.00094 19.5 13.9 0.057 13.7 3.4 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF996) DUF3481 PF11980.8 RLN77513.1 - 0.033 13.9 3.3 3.9 7.2 0.2 2.6 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein FAST_1 PF06743.15 RLN77513.1 - 0.24 11.4 2.3 8.7 6.4 0.1 2.6 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 DUF1772 PF08592.11 RLN77513.1 - 0.55 10.5 13.7 0.34 11.2 0.8 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) GASA PF02704.14 RLN77513.1 - 1.2 9.4 12.1 6.2 7.1 2.5 2.4 2 0 0 2 2 2 0 Gibberellin regulated protein DUF898 PF05987.13 RLN77513.1 - 3 6.8 25.8 4.5 6.2 9.6 3.6 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF898) CitMHS PF03600.16 RLN77513.1 - 4.6 6.4 19.0 39 3.3 19.0 2.1 1 1 0 1 1 1 0 Citrate transporter EcsC PF12787.7 RLN77513.1 - 4.7 6.8 4.9 29 4.2 0.0 3.1 3 1 1 4 4 4 0 EcsC protein family EI24 PF07264.11 RLN77514.1 - 9.4e-23 81.4 13.3 1.2e-22 81.0 13.3 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) ASFV_J13L PF05568.11 RLN77514.1 - 0.25 11.1 1.2 2.1 8.0 0.0 2.0 2 0 0 2 2 2 0 African swine fever virus J13L protein DUF996 PF06195.13 RLN77514.1 - 1.4 9.2 9.5 0.075 13.3 2.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF996) EcsC PF12787.7 RLN77514.1 - 3.9 7.1 6.6 0.4 10.3 0.3 2.2 2 1 1 3 3 3 0 EcsC protein family GAF_2 PF13185.6 RLN77527.1 - 1.2e-09 38.6 0.0 3.5e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 RLN77527.1 - 1.1e-05 26.0 0.1 1.6e-05 25.6 0.1 1.3 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 RLN77527.1 - 0.02 15.2 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 GAF domain Glyco_hydro_1 PF00232.18 RLN77528.1 - 7.4e-123 410.3 1.3 8.9e-123 410.0 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 VSP PF03302.13 RLN77528.1 - 0.0019 17.1 2.3 0.0019 17.1 2.3 1.6 2 0 0 2 2 2 1 Giardia variant-specific surface protein DAP10 PF07213.11 RLN77528.1 - 0.41 10.6 2.2 0.84 9.6 2.2 1.4 1 0 0 1 1 1 0 DAP10 membrane protein SseC PF04888.12 RLN77528.1 - 4.6 6.8 5.0 7.5 6.0 5.0 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Glyco_hydro_1 PF00232.18 RLN77529.1 - 2.7e-107 359.0 0.0 3.1e-107 358.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 GPCR_chapero_1 PF11904.8 RLN77530.1 - 2.8e-12 46.7 2.5 2.3e-11 43.7 2.5 2.0 1 1 0 1 1 1 1 GPCR-chaperone GOLD_2 PF13897.6 RLN77530.1 - 1.9e-10 41.4 3.4 7.6e-06 26.5 0.0 2.6 2 1 1 3 3 3 2 Golgi-dynamics membrane-trafficking BT1 PF03092.16 RLN77553.1 - 5.4e-07 28.2 2.6 6.6e-05 21.3 1.5 2.4 2 1 0 2 2 2 2 BT1 family Collagen PF01391.18 RLN77553.1 - 2.9 7.7 12.5 0.26 11.0 7.4 1.8 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) CopD PF05425.13 RLN77555.1 - 0.00012 22.5 2.7 0.21 12.0 0.1 2.2 2 0 0 2 2 2 2 Copper resistance protein D EphA2_TM PF14575.6 RLN77555.1 - 0.00024 21.9 0.1 0.48 11.4 0.0 2.4 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 RLN77555.1 - 0.00025 20.8 2.1 0.19 11.6 0.2 2.3 2 0 0 2 2 2 2 Lipopolysaccharide assembly protein A domain Tmemb_9 PF05434.11 RLN77555.1 - 0.00057 19.8 0.1 1.2 9.0 0.0 2.4 2 0 0 2 2 2 2 TMEM9 SNARE_assoc PF09335.11 RLN77555.1 - 0.00061 20.3 0.6 0.71 10.4 0.0 2.3 2 0 0 2 2 2 2 SNARE associated Golgi protein DUF456 PF04306.13 RLN77555.1 - 0.0013 19.0 0.5 0.16 12.3 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF456) MscL PF01741.18 RLN77555.1 - 0.002 18.4 0.0 0.21 11.9 0.0 2.1 2 0 0 2 2 2 1 Large-conductance mechanosensitive channel, MscL Amnionless PF14828.6 RLN77555.1 - 0.002 17.0 0.1 0.37 9.6 0.0 2.3 2 0 0 2 2 2 1 Amnionless FHIPEP PF00771.20 RLN77555.1 - 0.0023 16.5 0.4 0.052 12.0 0.0 2.0 2 0 0 2 2 2 1 FHIPEP family DUF4381 PF14316.6 RLN77555.1 - 0.0079 16.5 0.7 2.6 8.3 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) HemY_N PF07219.13 RLN77555.1 - 0.017 15.3 5.8 1.5 9.0 0.2 2.2 2 0 0 2 2 2 0 HemY protein N-terminus Colicin_V PF02674.16 RLN77555.1 - 0.023 14.7 1.0 2.3 8.2 0.1 2.2 2 0 0 2 2 2 0 Colicin V production protein Phage_holin_3_6 PF07332.11 RLN77555.1 - 0.046 13.8 0.9 11 6.1 0.1 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III WBP-1 PF11669.8 RLN77555.1 - 0.046 14.4 3.9 1.4 9.5 0.0 3.1 3 0 0 3 3 2 0 WW domain-binding protein 1 Phage_holin_2_4 PF16082.5 RLN77555.1 - 0.058 13.1 0.8 0.49 10.2 0.3 2.3 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like NnrU PF07298.11 RLN77555.1 - 0.079 12.5 2.3 4.2 6.8 0.2 2.2 2 0 0 2 2 2 0 NnrU protein DUF4865 PF16157.5 RLN77555.1 - 0.085 12.8 0.0 6 6.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4865) NicO PF03824.16 RLN77555.1 - 0.09 12.1 0.1 6.7 6.0 0.0 2.1 2 0 0 2 2 2 0 High-affinity nickel-transport protein DUF2615 PF11027.8 RLN77555.1 - 0.17 12.1 3.5 8.1 6.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) COX14 PF14880.6 RLN77555.1 - 0.21 11.5 1.0 15 5.5 0.1 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c assembly TraL PF07178.11 RLN77555.1 - 0.48 10.9 2.0 3.2 8.3 0.3 2.2 2 0 0 2 2 2 0 TraL protein DUF485 PF04341.12 RLN77555.1 - 0.66 10.0 2.6 16 5.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF485 DUF1651 PF07864.11 RLN77555.1 - 0.75 10.2 4.4 6.5 7.2 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1651) zf-3CxxC_2 PF17180.4 RLN77555.1 - 4.1 8.2 8.3 18 6.1 0.4 2.8 2 0 0 2 2 2 0 Zinc-binding domain DUF2840 PF11000.8 RLN77556.1 - 0.19 11.5 0.0 0.32 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2840) TMEM154 PF15102.6 RLN77557.1 - 0.0068 16.3 0.1 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 TMEM154 protein family BatD PF13584.6 RLN77557.1 - 0.036 12.9 0.0 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance PBP_N PF17093.5 RLN77557.1 - 0.044 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus EphA2_TM PF14575.6 RLN77557.1 - 0.15 13.0 0.0 0.3 12.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 RLN77557.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MAGE_N PF12440.8 RLN77558.1 - 2.9 8.6 8.3 3.3 8.4 2.6 2.4 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal DUF755 PF05501.11 RLN77558.1 - 4.4 7.6 5.7 6.4 7.1 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) FYVE_2 PF02318.16 RLN77584.1 - 0.77 10.0 6.7 1.6 9.0 4.1 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger FYVE PF01363.21 RLN77584.1 - 6.5 7.0 9.5 24 5.1 9.6 1.9 1 1 0 1 1 1 0 FYVE zinc finger FYVE PF01363.21 RLN77585.1 - 0.97 9.6 9.1 2.3 8.4 9.1 1.7 1 1 1 2 2 2 0 FYVE zinc finger FYVE_2 PF02318.16 RLN77586.1 - 4.5 7.5 7.3 1.7 8.9 4.4 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger FYVE PF01363.21 RLN77586.1 - 7.5 6.8 8.9 17 5.6 8.6 1.8 1 1 0 1 1 1 0 FYVE zinc finger DUF4780 PF16012.5 RLN77587.1 - 0.014 14.9 0.1 0.023 14.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4780) FYVE PF01363.21 RLN77587.1 - 2.5 8.3 7.4 7 6.9 7.1 1.9 1 1 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN77588.1 - 0.19 11.9 4.0 0.38 11.0 4.0 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 RLN77588.1 - 1.8 8.8 12.6 69 3.7 0.1 2.3 1 1 1 2 2 2 0 FYVE zinc finger FYVE PF01363.21 RLN77589.1 - 0.047 13.8 6.4 0.91 9.7 3.4 2.3 2 0 0 2 2 2 0 FYVE zinc finger His_Phos_1 PF00300.22 RLN77590.1 - 6.8e-33 114.0 0.0 5.3e-26 91.5 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) MCM PF00493.23 RLN77591.1 - 6.4e-99 329.6 0.1 1.1e-98 328.8 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RLN77591.1 - 2e-36 124.6 0.4 3.6e-36 123.8 0.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RLN77591.1 - 4.5e-27 94.3 0.0 2.1e-26 92.2 0.0 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 RLN77591.1 - 6.4e-13 49.2 0.0 1.8e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 RLN77591.1 - 4.4e-05 23.0 0.0 0.00025 20.5 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RLN77591.1 - 0.0046 16.8 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RLN77591.1 - 0.046 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CLASP_N PF12348.8 RLN77592.1 - 0.024 14.2 0.3 0.045 13.3 0.3 1.4 1 0 0 1 1 1 0 CLASP N terminal PK PF00224.21 RLN77593.1 - 8e-131 436.0 1.6 1.3e-130 435.4 1.6 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 RLN77593.1 - 2.6e-25 88.9 0.4 2e-23 82.9 0.1 2.7 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain MFS_1 PF07690.16 RLN77594.1 - 7.6e-30 104.0 44.3 6.1e-23 81.3 24.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 RLN77594.1 - 0.0006 18.3 6.8 0.0006 18.3 6.8 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector DUF3147 PF11345.8 RLN77594.1 - 0.029 14.7 2.2 0.029 14.7 2.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3147) MFS_1 PF07690.16 RLN77595.1 - 7.7e-36 123.7 29.6 4.2e-27 95.0 10.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN77595.1 - 2.3e-05 23.5 14.1 0.00067 18.6 0.5 3.2 3 0 0 3 3 3 3 Sugar (and other) transporter MFS_3 PF05977.13 RLN77595.1 - 0.013 13.9 11.9 0.0071 14.8 2.5 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Acyl_transf_3 PF01757.22 RLN77596.1 - 3.9e-11 42.6 41.9 5.4e-11 42.2 41.9 1.2 1 0 0 1 1 1 1 Acyltransferase family Lipase_GDSL_2 PF13472.6 RLN77597.1 - 2.6e-16 60.6 0.2 4.7e-16 59.7 0.2 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RLN77597.1 - 1.9e-15 57.4 0.0 3.4e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ank_2 PF12796.7 RLN77598.1 - 1.5e-38 131.3 4.3 8e-07 29.6 0.1 8.2 3 3 3 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN77598.1 - 1.3e-35 121.3 13.3 0.00026 21.5 0.1 12.1 9 3 5 14 14 14 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN77598.1 - 1.5e-29 101.6 19.9 0.004 17.4 0.1 14.9 8 3 9 17 17 17 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN77598.1 - 1.5e-26 89.5 6.7 1.4 9.7 0.0 14.8 14 2 2 16 16 16 5 Ankyrin repeat Ank PF00023.30 RLN77598.1 - 0.00016 22.0 4.0 1.1e+02 3.5 0.0 7.9 9 1 0 9 9 9 0 Ankyrin repeat DUF3322 PF11795.8 RLN77598.1 - 0.02 14.9 2.2 11 6.0 0.0 4.6 2 1 3 5 5 5 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Ank_2 PF12796.7 RLN77599.1 - 1.2e-37 128.3 8.1 1.5e-08 35.1 0.1 8.5 5 2 4 9 9 9 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN77599.1 - 1.6e-36 123.9 23.1 0.00024 21.3 0.1 14.6 10 3 6 16 16 16 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN77599.1 - 3.2e-36 123.2 15.9 8.7e-06 26.2 0.1 11.8 9 3 4 13 13 13 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN77599.1 - 2.1e-24 82.9 8.2 0.65 10.7 0.0 15.0 16 0 0 16 16 16 6 Ankyrin repeat Ank PF00023.30 RLN77599.1 - 0.0079 16.6 11.0 76 4.0 0.2 8.3 9 1 0 9 9 9 0 Ankyrin repeat FYVE PF01363.21 RLN77600.1 - 0.086 13.0 18.6 0.15 12.2 18.6 1.4 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN77600.1 - 0.42 10.8 12.0 0.83 9.9 12.0 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger IBR PF01485.21 RLN77600.1 - 0.56 10.5 11.7 0.21 11.9 7.1 2.2 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain FYVE PF01363.21 RLN77601.1 - 2.8 8.2 13.6 4.5 7.5 13.6 1.3 1 0 0 1 1 1 0 FYVE zinc finger FYVE PF01363.21 RLN77602.1 - 4.5 7.5 8.4 7.7 6.7 7.7 1.7 1 1 1 2 2 2 0 FYVE zinc finger FYVE PF01363.21 RLN77603.1 - 0.033 14.3 8.1 0.064 13.4 8.1 1.4 1 0 0 1 1 1 0 FYVE zinc finger FYVE PF01363.21 RLN77605.1 - 0.25 11.5 7.8 0.58 10.3 7.9 1.6 1 1 0 1 1 1 0 FYVE zinc finger Ank_2 PF12796.7 RLN77606.1 - 1.3e-40 137.8 5.8 4.9e-06 27.0 0.3 10.8 8 2 2 11 11 11 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN77606.1 - 4.5e-33 113.2 20.0 0.00061 20.3 0.0 14.5 13 5 3 16 16 16 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN77606.1 - 2.8e-30 104.0 23.2 0.0017 18.6 0.0 16.7 13 4 6 19 19 19 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN77606.1 - 5.5e-27 90.8 11.4 1.3 9.8 0.0 19.5 23 0 0 23 23 23 5 Ankyrin repeat Ank PF00023.30 RLN77606.1 - 0.00024 21.4 5.0 1.1e+02 3.5 0.0 8.4 10 0 0 10 10 10 0 Ankyrin repeat DUF5049 PF16468.5 RLN77606.1 - 0.13 12.2 0.0 16 5.5 0.0 4.4 5 1 0 5 5 5 0 Domain of unknown function (DUF5049) McrBC PF10117.9 RLN77606.1 - 0.26 10.4 0.5 26 3.8 0.0 3.1 4 0 0 4 4 4 0 McrBC 5-methylcytosine restriction system component FYVE PF01363.21 RLN77607.1 - 0.085 13.0 9.0 0.17 12.0 9.0 1.5 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN77607.1 - 0.47 10.7 6.6 0.92 9.7 6.6 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger DUF4094 PF13334.6 RLN77608.1 - 0.047 14.1 2.5 6.2 7.3 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) FYVE_2 PF02318.16 RLN77609.1 - 1.8 8.8 6.8 3.3 7.9 6.8 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger PatG_D PF18047.1 RLN77610.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 PatG Domain FYVE PF01363.21 RLN77610.1 - 1.1 9.5 13.7 2 8.6 13.7 1.4 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN77610.1 - 6 7.1 11.7 25 5.1 11.6 2.0 1 1 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 RLN77611.1 - 0.082 13.1 11.0 0.2 11.8 11.0 1.7 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN77611.1 - 0.43 10.8 8.6 0.82 9.9 8.6 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Bromodomain PF00439.25 RLN77625.1 - 2.2e-19 69.3 0.2 1.1e-18 67.1 0.3 2.0 2 0 0 2 2 2 1 Bromodomain PHD PF00628.29 RLN77625.1 - 5.3e-07 29.4 6.0 1.4e-06 28.0 6.0 1.8 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 RLN77625.1 - 0.018 15.3 1.7 0.04 14.2 1.7 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Zf_RING PF16744.5 RLN77625.1 - 0.062 13.4 2.7 0.16 12.1 2.7 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger zf-PHD-like PF15446.6 RLN77625.1 - 0.078 12.6 2.4 0.15 11.7 2.4 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-4CXXC_R1 PF10497.9 RLN77625.1 - 0.15 12.3 1.4 0.3 11.4 1.4 1.5 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 PHD_4 PF16866.5 RLN77625.1 - 0.64 10.1 3.9 1.9 8.6 3.9 1.8 1 0 0 1 1 1 0 PHD-finger PPP4R2 PF09184.11 RLN77625.1 - 2.9 7.4 10.3 6.8 6.2 10.3 1.6 1 0 0 1 1 1 0 PPP4R2 PI3_PI4_kinase PF00454.27 RLN77641.1 - 3.8e-26 92.4 0.0 3.5e-22 79.4 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase ubiquitin PF00240.23 RLN77641.1 - 1.4e-09 37.6 1.3 1.7e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family PHTB1_N PF14727.6 RLN77642.1 - 2.1e-74 251.4 0.0 2.3e-74 251.2 0.0 1.0 1 0 0 1 1 1 1 PTHB1 N-terminus RCC1 PF00415.18 RLN77643.1 - 9.7e-47 157.4 25.0 9.2e-11 42.2 0.2 7.9 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat PP2C PF00481.21 RLN77643.1 - 1.5e-36 126.4 0.0 3.8e-36 125.0 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C RCC1_2 PF13540.6 RLN77643.1 - 2.2e-26 91.0 36.6 5.3e-10 38.8 0.2 7.4 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 RLN77643.1 - 2.1e-05 25.0 0.2 0.00016 22.2 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 RLN77643.1 - 8.4e-05 22.8 0.3 0.00021 21.6 0.3 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 RLN77643.1 - 0.0001 22.4 0.1 0.00043 20.5 0.1 2.1 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 RLN77643.1 - 0.00031 21.3 0.0 0.0015 19.1 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN77643.1 - 0.0007 19.8 0.3 0.0017 18.6 0.3 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Thx PF17070.5 RLN77643.1 - 0.074 13.2 0.4 0.27 11.4 0.4 1.9 1 0 0 1 1 1 0 30S ribosomal protein Thx DUF4698 PF15769.5 RLN77644.1 - 0.00013 21.2 0.3 0.00021 20.5 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4698) Glyoxalase PF00903.25 RLN77701.1 - 0.00053 20.2 0.1 0.073 13.3 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 RLN77701.1 - 0.011 16.0 0.0 2.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 RLN77701.1 - 0.14 12.3 0.1 2.7 8.1 0.0 2.6 2 1 0 2 2 2 0 Glyoxalase-like domain Sec20 PF03908.13 RLN77703.1 - 6.3e-12 45.3 0.4 3e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 Sec20 EPOP PF15223.6 RLN77703.1 - 0.065 12.6 2.1 0.083 12.2 2.1 1.1 1 0 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein DUF2894 PF11445.8 RLN77703.1 - 0.12 12.9 3.9 0.19 12.2 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Fasciclin PF02469.22 RLN77703.1 - 0.14 12.4 0.2 0.23 11.7 0.2 1.5 1 0 0 1 1 1 0 Fasciclin domain STAT_alpha PF01017.20 RLN77703.1 - 0.53 10.2 6.2 1.5 8.7 0.2 2.2 1 1 1 2 2 2 0 STAT protein, all-alpha domain DUF3416 PF11896.8 RLN77703.1 - 0.66 10.2 5.3 0.7 10.2 3.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF3416) VPS13_C PF16909.5 RLN77704.1 - 3.3e-48 163.8 1.9 1.7e-45 155.0 0.1 2.8 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 RLN77704.1 - 9e-47 159.8 2.1 9.6e-22 77.9 0.0 4.0 4 0 0 4 4 4 3 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 RLN77704.1 - 7.7e-23 80.8 0.0 2.4e-22 79.2 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 RLN77704.1 - 5.8e-22 78.3 0.0 1.7e-19 70.3 0.0 3.1 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 RLN77704.1 - 2.8e-21 76.0 2.7 4.2e-20 72.2 0.0 3.8 5 0 0 5 5 5 1 Repeating coiled region of VPS13 PX PF00787.24 RLN77704.1 - 1.1e-12 47.9 0.0 2.6e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 PX domain ATG_C PF09333.11 RLN77704.1 - 0.0033 17.7 0.0 0.013 15.9 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Fmp27 PF10344.9 RLN77704.1 - 0.039 12.0 0.0 0.077 11.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 RabGAP-TBC PF00566.18 RLN77721.1 - 5.9e-28 98.0 4.1 1.9e-27 96.3 0.1 2.4 3 0 0 3 3 3 2 Rab-GTPase-TBC domain PH PF00169.29 RLN77721.1 - 9.9e-05 22.8 0.1 0.00036 21.0 0.0 2.0 2 0 0 2 2 2 1 PH domain zf-C3HC4_2 PF13923.6 RLN77722.1 - 4.7e-12 45.5 9.5 7.4e-12 44.9 9.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN77722.1 - 4.8e-09 36.4 8.9 8.5e-09 35.6 8.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RLN77722.1 - 9.5e-08 31.8 10.0 1.6e-07 31.1 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN77722.1 - 3.1e-07 30.1 9.7 5.3e-07 29.4 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN77722.1 - 5.6e-07 29.5 6.1 1.1e-06 28.5 6.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN77722.1 - 1.7e-06 27.9 9.4 2.8e-06 27.2 9.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RLN77722.1 - 9.8e-06 25.3 9.5 1.6e-05 24.6 9.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 RLN77722.1 - 1.8e-05 24.8 8.7 3.8e-05 23.7 8.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 RLN77722.1 - 5.3e-05 23.0 3.2 8.7e-05 22.3 3.2 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 RLN77722.1 - 0.0014 18.8 8.0 0.004 17.4 8.1 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 RLN77722.1 - 0.005 16.6 5.3 0.011 15.5 5.3 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain Nop14 PF04147.12 RLN77722.1 - 0.013 13.7 1.9 0.015 13.6 1.9 1.1 1 0 0 1 1 1 0 Nop14-like family zf-Nse PF11789.8 RLN77722.1 - 0.016 15.0 5.4 0.026 14.3 5.4 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit CDC45 PF02724.14 RLN77722.1 - 0.019 13.3 3.8 0.026 12.9 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-RING_10 PF16685.5 RLN77722.1 - 0.021 15.0 7.3 0.035 14.2 7.3 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 YL1 PF05764.13 RLN77722.1 - 0.028 14.5 2.9 0.036 14.2 2.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein MAM33 PF02330.16 RLN77722.1 - 0.054 13.4 0.1 0.079 12.9 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial glycoprotein zf-RING_11 PF17123.5 RLN77722.1 - 0.12 12.2 6.0 0.27 11.0 6.0 1.6 1 0 0 1 1 1 0 RING-like zinc finger LAT PF15234.6 RLN77722.1 - 0.12 12.1 4.6 0.23 11.2 4.6 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells Rubredoxin_2 PF18073.1 RLN77722.1 - 0.16 11.7 1.4 0.34 10.7 1.4 1.5 1 0 0 1 1 1 0 Rubredoxin metal binding domain zinc-ribbons_6 PF07191.12 RLN77722.1 - 0.31 11.0 4.1 0.6 10.1 4.1 1.5 1 0 0 1 1 1 0 zinc-ribbons FAM176 PF14851.6 RLN77722.1 - 0.32 10.7 3.4 0.62 9.7 3.4 1.4 1 0 0 1 1 1 0 FAM176 family BUD22 PF09073.10 RLN77722.1 - 0.4 10.0 3.4 0.54 9.5 3.4 1.2 1 0 0 1 1 1 0 BUD22 Utp14 PF04615.13 RLN77722.1 - 1.4 7.4 6.3 1.8 7.0 6.3 1.1 1 0 0 1 1 1 0 Utp14 protein RXT2_N PF08595.11 RLN77722.1 - 1.4 8.9 4.6 2.7 8.0 4.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 RLN77722.1 - 1.8 6.6 12.5 2.5 6.1 12.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 RLN77722.1 - 1.9 8.2 12.6 3.1 7.5 12.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-P11 PF03854.14 RLN77722.1 - 3.5 7.4 7.3 7.2 6.4 7.3 1.5 1 1 0 1 1 1 0 P-11 zinc finger Ank_2 PF12796.7 RLN77816.1 - 2e-24 86.0 0.3 4.5e-14 52.8 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN77816.1 - 5.7e-18 64.8 4.1 0.0002 21.6 0.0 4.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN77816.1 - 2.4e-17 62.5 4.1 0.00012 22.4 0.1 5.5 5 0 0 5 5 5 3 Ankyrin repeat FYVE PF01363.21 RLN77816.1 - 1.5e-16 60.3 13.9 2.3e-16 59.7 13.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger Ank_3 PF13606.6 RLN77816.1 - 2.5e-15 55.0 0.7 0.013 16.0 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 RLN77816.1 - 8e-13 48.6 4.5 6.1e-08 33.1 0.0 5.0 4 2 2 6 6 6 2 Ankyrin repeats (many copies) FYVE_2 PF02318.16 RLN77816.1 - 0.89 9.8 13.0 1.3 9.3 11.7 1.8 1 1 1 2 2 2 0 FYVE-type zinc finger Pkinase PF00069.25 RLN77817.1 - 1.2e-77 260.8 0.0 1.9e-77 260.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 RLN77817.1 - 3.4e-47 158.7 23.0 2.1e-13 50.4 0.1 10.8 10 0 0 10 10 10 8 Fibronectin type III domain Pkinase_Tyr PF07714.17 RLN77817.1 - 4.4e-43 147.4 0.0 8e-43 146.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 RLN77817.1 - 1.3e-12 46.9 0.0 0.0029 17.7 0.0 6.3 6 0 0 6 6 5 3 HEAT repeat Pur_ac_phosph_N PF16656.5 RLN77817.1 - 1.7e-12 47.7 5.0 0.00028 21.4 0.1 7.3 7 1 0 7 7 7 2 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 RLN77817.1 - 2.4e-10 40.7 1.1 0.011 16.1 0.0 6.3 7 0 0 7 7 7 2 Uncharacterised conserved protein (DUF2369) HEAT_EZ PF13513.6 RLN77817.1 - 3.9e-09 36.8 0.0 0.0003 21.2 0.0 3.4 2 0 0 2 2 2 2 HEAT-like repeat Ephrin_rec_like PF07699.13 RLN77817.1 - 5.4e-07 29.3 17.2 0.014 15.2 2.9 3.7 1 1 2 3 3 3 3 Putative ephrin-receptor like Arm PF00514.23 RLN77817.1 - 1.1e-06 28.4 4.3 0.09 12.8 0.0 5.1 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN77817.1 - 2.3e-06 27.9 0.0 0.0034 17.7 0.0 4.4 4 1 1 5 5 4 2 HEAT repeats Pkinase_fungal PF17667.1 RLN77817.1 - 2.5e-05 23.3 0.0 4.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN77817.1 - 0.003 16.9 0.0 0.013 14.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 RLN77817.1 - 0.0032 16.5 0.3 0.0054 15.7 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RLN77817.1 - 0.058 13.3 0.0 0.21 11.5 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN77817.1 - 0.23 10.8 0.1 0.42 9.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Furin-like PF00757.20 RLN77817.1 - 0.37 10.7 5.1 0.87 9.4 5.1 1.6 1 0 0 1 1 1 0 Furin-like cysteine rich region NCD3G PF07562.14 RLN77817.1 - 2.5 8.1 11.5 5.8 7.0 2.6 3.0 3 0 0 3 3 3 0 Nine Cysteines Domain of family 3 GPCR AAA_9 PF12781.7 RLN77840.1 - 1.7e-87 292.2 0.1 1.9e-86 288.8 0.4 2.2 2 0 0 2 2 2 1 ATP-binding dynein motor region Dynein_heavy PF03028.15 RLN77840.1 - 3.1e-43 146.7 0.1 2.6e-41 140.4 0.0 2.9 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 RLN77840.1 - 4.6e-29 101.3 0.2 1.1e-28 100.1 0.2 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 RLN77840.1 - 1.5e-23 83.4 0.3 2.7e-23 82.5 0.3 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor UPF0242 PF06785.11 RLN77840.1 - 0.0039 17.3 1.0 0.0095 16.1 1.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus ADAM_spacer1 PF05986.14 RLN77840.1 - 0.23 11.5 1.1 0.85 9.7 0.0 2.3 2 1 1 3 3 3 0 ADAM-TS Spacer 1 DUF2183 PF09949.9 RLN77855.1 - 0.0033 17.7 0.0 6.7 7.1 0.0 3.1 2 1 1 3 3 3 2 Uncharacterized conserved protein (DUF2183) ABC2_membrane_3 PF12698.7 RLN77865.1 - 3.9e-20 72.3 32.9 5.5e-19 68.5 32.9 2.5 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 RLN77865.1 - 0.00051 19.5 24.7 0.00054 19.5 22.1 2.2 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_5 PF13346.6 RLN77865.1 - 0.099 12.2 22.1 0.18 11.3 22.1 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein BPD_transp_1 PF00528.22 RLN77865.1 - 2.7 7.7 20.6 15 5.3 20.6 2.1 1 1 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component VIT1 PF01988.19 RLN77865.1 - 2.8 7.7 6.8 1.4 8.7 4.1 1.9 2 0 0 2 2 2 0 VIT family PDEase_I PF00233.19 RLN77882.1 - 3.6e-51 174.2 0.0 4.1e-50 170.7 0.0 2.1 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 RLN77882.1 - 1.2e-20 74.5 7.4 2.9e-06 28.0 0.0 5.5 4 1 0 4 4 4 4 GAF domain GAF_2 PF13185.6 RLN77882.1 - 2.2e-20 73.4 12.1 6.5e-07 29.7 0.0 6.1 5 1 0 5 5 5 4 GAF domain GAF_3 PF13492.6 RLN77882.1 - 2.5e-15 56.9 4.5 4.7e-05 23.7 0.0 4.7 5 0 0 5 5 5 3 GAF domain Copine PF07002.16 RLN77883.1 - 8.6e-57 192.1 0.0 1.2e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 RLN77883.1 - 7.6e-11 42.5 0.0 1.2e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus mTERF PF02536.14 RLN77883.1 - 0.19 10.6 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 mTERF AhpC-TSA PF00578.21 RLN77884.1 - 2.6e-36 124.3 0.0 1.1e-32 112.6 0.0 2.2 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin PF00085.20 RLN77884.1 - 2.7e-19 69.1 0.0 4.4e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 RLN77884.1 - 2e-15 56.8 0.0 7.5e-12 45.2 0.0 2.2 2 0 0 2 2 2 2 Redoxin 1-cysPrx_C PF10417.9 RLN77884.1 - 1.1e-13 50.8 0.0 2.5e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Thioredoxin_2 PF13098.6 RLN77884.1 - 8.2e-05 23.0 0.2 0.00057 20.3 0.1 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 RLN77884.1 - 0.00047 19.9 0.0 0.00094 19.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 RLN77884.1 - 0.028 14.7 0.0 0.38 11.1 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin-like Copine PF07002.16 RLN77885.1 - 1.8e-30 106.1 0.0 4.5e-19 68.8 0.0 2.5 2 1 0 2 2 2 2 Copine MarB PF13999.6 RLN77885.1 - 0.018 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 MarB protein G-patch PF01585.23 RLN77886.1 - 4.2e-12 45.7 6.6 1.2e-11 44.3 6.6 1.9 1 0 0 1 1 1 1 G-patch domain OCRE PF17780.1 RLN77886.1 - 7.1e-08 32.4 6.9 1.4e-07 31.5 6.9 1.3 1 0 0 1 1 1 1 OCRE domain G-patch_2 PF12656.7 RLN77886.1 - 0.00042 20.3 3.6 0.00042 20.3 3.6 2.4 2 0 0 2 2 2 1 G-patch domain Copine PF07002.16 RLN77887.1 - 1.6e-52 178.1 0.1 6.3e-37 127.1 0.0 2.0 2 0 0 2 2 2 2 Copine vWA-TerF-like PF10138.9 RLN77887.1 - 3e-09 37.3 0.0 5.9e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 vWA found in TerF C terminus VWA PF00092.28 RLN77887.1 - 0.048 13.9 0.0 0.066 13.5 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain MMPL PF03176.15 RLN77887.1 - 0.18 10.7 0.2 0.25 10.2 0.2 1.1 1 0 0 1 1 1 0 MMPL family Metallophos PF00149.28 RLN77888.1 - 6.2e-12 46.4 0.5 1.1e-11 45.7 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 RLN77888.1 - 8.7e-06 26.5 0.6 6e-05 23.8 0.1 2.6 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 RLN77888.1 - 1.1e-05 25.8 1.8 1.1e-05 25.8 1.8 2.4 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 RLN77888.1 - 0.00044 20.5 0.0 0.043 14.0 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 RLN77889.1 - 1.2e-05 25.9 0.2 0.00027 21.5 0.2 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 RLN77889.1 - 2e-05 25.1 0.8 2e-05 25.1 0.8 2.5 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 RLN77889.1 - 3e-05 24.8 2.3 5.3e-05 24.0 0.1 2.7 3 0 0 3 3 3 1 Iron/zinc purple acid phosphatase-like protein C Ank_2 PF12796.7 RLN77890.1 - 2.4e-37 127.4 0.0 1.6e-14 54.3 0.0 6.2 3 1 3 7 7 7 4 Ankyrin repeats (3 copies) TIR_2 PF13676.6 RLN77890.1 - 7.1e-32 110.5 0.1 5.9e-18 65.6 0.0 3.0 3 0 0 3 3 3 2 TIR domain Ank_4 PF13637.6 RLN77890.1 - 3.9e-30 103.8 2.0 4.6e-08 33.4 0.1 7.5 5 1 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN77890.1 - 2.5e-28 95.0 1.2 6.6e-05 23.0 0.0 8.9 8 1 1 9 9 9 5 Ankyrin repeat Ank PF00023.30 RLN77890.1 - 4.2e-24 83.9 5.6 0.0004 20.7 0.0 8.5 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 RLN77890.1 - 2.1e-22 78.9 6.4 7.5e-06 26.1 0.1 7.6 5 1 2 7 7 7 5 Ankyrin repeats (many copies) TIR PF01582.20 RLN77890.1 - 4.9e-09 36.2 0.1 3.3e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 TIR domain DUF1863 PF08937.11 RLN77890.1 - 5e-06 26.8 0.0 0.015 15.6 0.1 2.9 2 1 0 2 2 2 2 MTH538 TIR-like domain (DUF1863) Pkinase_Tyr PF07714.17 RLN77935.1 - 2.4e-15 56.6 0.0 5e-15 55.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN77935.1 - 1.4e-13 50.8 0.0 2.1e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 RLN77935.1 - 0.034 13.5 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Voltage_CLC PF00654.20 RLN77936.1 - 7.1e-16 58.4 9.3 8.5e-16 58.1 9.3 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel DUF3458_C PF17432.2 RLN77947.1 - 1.4e-14 54.2 0.0 1.6e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats VPS13_C PF16909.5 RLN77948.1 - 2.5e-16 60.0 0.0 5.6e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 RLN77950.1 - 6.8e-26 91.5 0.0 1.3e-25 90.5 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 RLN77950.1 - 2.5e-15 56.6 0.0 2.9e-13 49.8 0.0 2.7 2 1 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 RLN77950.1 - 1.1e-13 51.3 0.1 2.7e-13 50.0 0.1 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 PDZ_6 PF17820.1 RLN77950.1 - 0.0059 16.4 0.0 0.25 11.2 0.0 2.6 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 RLN77950.1 - 0.13 12.7 0.0 3 8.3 0.0 2.8 2 0 0 2 2 2 0 PDZ domain IQ PF00612.27 RLN77950.1 - 0.46 10.4 1.7 1.7 8.7 1.7 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif Metallophos PF00149.28 RLN77970.1 - 1.7e-18 67.9 0.2 2.4e-18 67.4 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 RLN77970.1 - 3.9e-11 43.6 0.0 1.1e-10 42.2 0.0 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 RLN77970.1 - 0.00032 20.9 0.0 0.014 15.6 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.10 RLN77970.1 - 0.0011 18.1 0.0 0.4 9.6 0.0 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase Pkinase_Tyr PF07714.17 RLN77971.1 - 1.7e-17 63.6 0.0 2e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN77971.1 - 9.2e-15 54.7 0.0 1.1e-14 54.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RLN77971.1 - 0.00015 21.2 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Bac_DNA_binding PF00216.21 RLN77971.1 - 0.042 14.0 0.0 0.1 12.8 0.0 1.6 2 0 0 2 2 2 0 Bacterial DNA-binding protein FlxA PF14282.6 RLN78083.1 - 1.3 9.1 5.7 2.2 8.3 3.0 2.7 1 1 1 2 2 2 0 FlxA-like protein DUF4537 PF15057.6 RLN78084.1 - 4.7e-05 23.4 0.4 0.15 12.1 0.0 4.9 6 0 0 6 6 6 1 Domain of unknown function (DUF4537) 53-BP1_Tudor PF09038.10 RLN78084.1 - 0.0011 18.9 0.0 0.0062 16.5 0.0 2.2 2 0 0 2 2 2 1 Tumour suppressor p53-binding protein-1 Tudor LPD30 PF18850.1 RLN78084.1 - 0.0028 17.4 0.0 11 5.8 0.0 4.2 4 0 0 4 4 4 2 Large polyvalent protein associated domain 30 DUF1325 PF07039.11 RLN78084.1 - 0.0031 17.6 0.6 6.9 6.8 0.0 3.6 3 0 0 3 3 3 2 SGF29 tudor-like domain Tudor_2 PF18104.1 RLN78084.1 - 0.0037 16.9 1.1 0.31 10.8 0.0 3.7 3 0 0 3 3 3 1 Jumonji domain-containing protein 2A Tudor domain TUDOR_5 PF18359.1 RLN78084.1 - 0.015 15.0 0.3 0.054 13.2 0.3 2.0 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 LBR_tudor PF09465.10 RLN78084.1 - 0.017 14.9 0.2 0.23 11.3 0.0 2.7 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain DUF2737 PF10930.8 RLN78084.1 - 0.064 12.8 0.9 5.2 6.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2737) VASt PF16016.5 RLN78084.1 - 0.16 12.4 0.1 6.9 7.1 0.0 2.6 2 0 0 2 2 2 0 VAD1 Analog of StAR-related lipid transfer domain SWIM PF04434.17 RLN78085.1 - 0.011 15.4 2.5 0.026 14.2 2.5 1.6 1 0 0 1 1 1 0 SWIM zinc finger DDE_Tnp_ISL3 PF01610.17 RLN78085.1 - 0.032 13.9 0.2 0.069 12.9 0.2 1.5 1 0 0 1 1 1 0 Transposase MULE PF10551.9 RLN78085.1 - 0.043 14.2 0.0 0.17 12.3 0.0 2.0 2 0 0 2 2 2 0 MULE transposase domain DUF5575 PF17738.1 RLN78085.1 - 0.051 12.6 1.9 0.43 9.6 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5575) Tubulin PF00091.25 RLN78086.1 - 2.7e-40 138.7 0.0 1.7e-39 136.1 0.0 2.0 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Dynamitin PF04912.14 RLN78086.1 - 0.11 11.8 0.3 0.19 11.0 0.1 1.4 2 0 0 2 2 2 0 Dynamitin UQ_con PF00179.26 RLN78087.1 - 3.7e-50 169.2 0.0 4.2e-50 169.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RLN78087.1 - 0.0033 17.1 0.0 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 RLN78087.1 - 0.029 14.2 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 RLN78087.1 - 0.058 13.7 0.0 0.089 13.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain Syntaxin_2 PF14523.6 RLN78088.1 - 6.2e-17 61.8 10.2 1.7e-16 60.5 4.4 2.2 2 0 0 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.25 RLN78088.1 - 9.9e-05 22.1 11.3 0.0067 16.1 2.4 2.6 3 0 0 3 3 3 2 Syntaxin SNARE PF05739.19 RLN78088.1 - 0.0027 17.6 7.3 0.0087 16.0 7.3 2.0 1 1 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.21 RLN78088.1 - 0.0048 16.7 2.5 0.0083 15.9 0.6 2.3 2 0 0 2 2 2 1 Synaptobrevin HsbA PF12296.8 RLN78088.1 - 0.0075 16.7 2.6 0.25 11.8 0.2 2.3 2 0 0 2 2 2 1 Hydrophobic surface binding protein A DUF1732 PF08340.11 RLN78088.1 - 0.04 13.9 0.5 0.04 13.9 0.5 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1732) COG2 PF06148.11 RLN78088.1 - 0.058 13.5 3.6 2.6 8.1 0.5 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 RLN78088.1 - 0.076 13.3 8.6 3.7 7.9 1.7 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Sec8_exocyst PF04048.14 RLN78088.1 - 0.1 12.5 5.4 1.2 9.1 0.3 3.4 2 2 0 3 3 3 0 Sec8 exocyst complex component specific domain DUF4665 PF15679.5 RLN78088.1 - 0.11 13.1 6.3 2.3 8.9 0.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4665) ING PF12998.7 RLN78088.1 - 0.14 12.7 4.5 1.6 9.4 0.4 2.6 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF2564 PF10819.8 RLN78088.1 - 0.19 12.1 2.0 7.7 7.0 0.0 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF2564) TRIQK PF15168.6 RLN78088.1 - 0.23 11.4 2.8 0.31 10.9 0.2 2.4 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family LXG PF04740.12 RLN78088.1 - 0.26 11.0 6.1 0.45 10.2 1.4 2.4 2 1 0 2 2 2 0 LXG domain of WXG superfamily CorA PF01544.18 RLN78088.1 - 0.37 10.1 2.6 0.78 9.0 0.8 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Seryl_tRNA_N PF02403.22 RLN78088.1 - 0.41 10.9 8.7 1.5 9.1 0.4 3.0 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TACC_C PF05010.14 RLN78088.1 - 0.43 10.3 8.0 0.43 10.4 0.5 2.8 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF3106 PF11304.8 RLN78088.1 - 0.71 10.4 3.1 0.67 10.5 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) YtxH PF12732.7 RLN78088.1 - 0.95 10.0 3.8 29 5.3 0.3 2.9 2 1 0 2 2 2 0 YtxH-like protein TMCO5 PF14992.6 RLN78088.1 - 1.1 8.7 5.1 6.9 6.2 0.3 2.2 1 1 0 2 2 2 0 TMCO5 family CdvA PF18822.1 RLN78088.1 - 2 8.3 7.9 2.4 8.0 0.4 3.5 2 2 1 4 4 4 0 CdvA-like coiled-coil domain DUF2570 PF10828.8 RLN78088.1 - 2.9 7.7 9.4 0.87 9.4 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2570) Fez1 PF06818.15 RLN78088.1 - 3.5 8.0 9.2 2.6 8.4 1.1 2.2 2 0 0 2 2 2 0 Fez1 TMPIT PF07851.13 RLN78088.1 - 7.5 5.7 5.9 3.1 7.0 1.0 2.1 2 0 0 2 2 2 0 TMPIT-like protein Ras PF00071.22 RLN78089.1 - 1.5e-28 99.4 0.0 3.4e-28 98.3 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RLN78089.1 - 2.4e-18 66.5 0.0 1.7e-17 63.7 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN78089.1 - 2.1e-07 30.6 0.0 4.4e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RLN78089.1 - 0.0035 16.7 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 RLN78089.1 - 0.026 14.0 0.0 0.12 11.8 0.0 2.0 2 1 1 3 3 3 0 P-loop containing dynein motor region AAA_16 PF13191.6 RLN78089.1 - 0.027 14.8 0.0 0.079 13.3 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 RLN78089.1 - 0.055 12.7 0.0 0.086 12.1 0.0 1.3 1 0 0 1 1 1 0 Septin TniB PF05621.11 RLN78089.1 - 0.082 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein MMR_HSR1 PF01926.23 RLN78089.1 - 0.16 12.1 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase zf-TAZ PF02135.16 RLN78090.1 - 0.0012 19.3 27.4 0.016 15.7 7.9 2.8 2 0 0 2 2 2 2 TAZ zinc finger DUF3813 PF12758.7 RLN78090.1 - 0.059 13.7 1.0 0.18 12.1 1.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) MukF_M PF17192.4 RLN78090.1 - 2 8.2 5.2 4.5 7.0 0.1 2.5 2 1 0 2 2 2 0 MukF middle domain UPF0052 PF01933.18 RLN78091.1 - 9.3e-85 284.4 0.0 1.4e-84 283.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 HAD_2 PF13419.6 RLN78091.1 - 1.8e-06 28.2 0.0 3.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RLN78091.1 - 0.00027 21.3 0.0 0.00054 20.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DENN PF02141.21 RLN78092.1 - 7e-32 110.9 0.9 2.4e-31 109.2 0.9 2.0 1 1 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 RLN78092.1 - 0.0004 20.3 0.7 0.0012 18.7 0.7 1.9 1 0 0 1 1 1 1 dDENN domain RGS PF00615.19 RLN78092.1 - 0.00044 20.5 2.2 0.7 10.2 0.0 3.0 2 1 0 2 2 2 2 Regulator of G protein signaling domain Vps51 PF08700.11 RLN78093.1 - 2.9e-23 81.7 0.3 5.6e-23 80.8 0.3 1.5 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 RLN78093.1 - 4e-08 32.3 0.9 5.1e-08 32.0 0.9 1.1 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.6 RLN78093.1 - 3.6e-06 26.9 0.6 5.8e-06 26.2 0.3 1.4 1 1 0 1 1 1 1 Exocyst complex component Sec5 COG2 PF06148.11 RLN78093.1 - 9.2e-06 25.8 0.8 1.2e-05 25.4 0.8 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 BORCS6 PF10157.9 RLN78093.1 - 2.1e-05 24.8 0.6 2.4e-05 24.6 0.6 1.2 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 COG5 PF10392.9 RLN78093.1 - 2.3e-05 24.6 0.7 3.4e-05 24.0 0.4 1.5 1 1 1 2 2 2 1 Golgi transport complex subunit 5 LIF_OSM PF01291.17 RLN78093.1 - 0.017 15.3 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 LIF / OSM family HIP1_clath_bdg PF16515.5 RLN78093.1 - 0.018 15.6 0.3 0.018 15.6 0.3 1.6 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Zw10 PF06248.13 RLN78093.1 - 0.026 13.1 0.3 0.032 12.8 0.3 1.0 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 KASH_CCD PF14662.6 RLN78093.1 - 0.053 13.4 1.5 0.085 12.7 0.3 1.8 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH LOH1CR12 PF10158.9 RLN78093.1 - 0.064 13.3 1.4 0.16 12.0 1.2 1.8 1 1 1 2 2 2 0 Tumour suppressor protein BRE1 PF08647.11 RLN78093.1 - 0.11 12.6 1.3 0.84 9.7 0.6 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DEAD PF00270.29 RLN78094.1 - 2.4e-43 147.9 0.0 6.9e-43 146.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN78094.1 - 1.1e-22 80.5 0.0 3.4e-22 78.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 RLN78094.1 - 3.3e-17 62.4 0.1 7.3e-17 61.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 RLN78094.1 - 5.4e-06 26.5 0.2 8.5e-05 22.6 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PDEase_I PF00233.19 RLN78095.1 - 8.1e-67 225.4 1.2 9.9e-67 225.1 1.2 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 RLN78095.1 - 0.066 13.4 0.6 0.15 12.3 0.6 1.6 1 0 0 1 1 1 0 HD domain Phage_tail_T PF06223.12 RLN78096.1 - 0.016 15.7 0.4 0.038 14.5 0.4 1.6 1 0 0 1 1 1 0 Minor tail protein T zf-HC5HC2H_2 PF13832.6 RLN78108.1 - 1.1e-38 131.7 78.4 8.8e-19 67.7 6.0 8.6 7 2 1 9 9 9 4 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RLN78108.1 - 3.5e-24 84.9 27.8 2.2e-13 50.3 2.8 9.0 8 1 1 9 9 9 3 PHD-like zinc-binding domain PHD_2 PF13831.6 RLN78108.1 - 2.1e-19 68.7 14.0 5.6e-14 51.4 1.7 6.4 6 0 0 6 6 6 3 PHD-finger PHD PF00628.29 RLN78108.1 - 2.7e-16 59.2 95.8 3e-08 33.4 4.8 9.5 8 0 0 8 8 8 4 PHD-finger FYVE_2 PF02318.16 RLN78108.1 - 0.00027 21.1 0.3 0.00027 21.1 0.3 6.8 8 0 0 8 8 8 1 FYVE-type zinc finger C1_1 PF00130.22 RLN78108.1 - 0.011 15.6 0.9 0.011 15.6 0.9 9.7 10 3 1 11 11 11 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1266 PF06889.11 RLN78108.1 - 0.33 11.0 2.3 0.29 11.2 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) Kinesin PF00225.23 RLN78109.1 - 3.4e-91 305.6 0.5 8.1e-91 304.4 0.5 1.6 1 0 0 1 1 1 1 Kinesin motor domain HgmA PF04209.13 RLN78109.1 - 1.2e-69 235.0 0.2 1.6e-46 158.9 0.3 2.2 2 0 0 2 2 2 2 homogentisate 1,2-dioxygenase Microtub_bd PF16796.5 RLN78109.1 - 4.7e-21 75.3 0.2 1.8e-15 57.1 0.1 2.6 1 1 1 2 2 2 2 Microtubule binding MMTV_SAg PF01054.17 RLN78109.1 - 0.022 14.3 0.4 0.057 13.0 0.4 1.7 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen Adenylate_cycl PF01295.18 RLN78109.1 - 0.023 13.3 2.1 0.038 12.6 2.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase, class-I DUF724 PF05266.14 RLN78109.1 - 0.15 11.9 10.8 0.31 10.8 10.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 RLN78109.1 - 1 9.4 11.4 2.5 8.2 11.4 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Rhodanese PF00581.20 RLN78110.1 - 0.0016 18.9 0.0 0.0032 18.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.20 RLN78110.1 - 0.003 17.4 0.0 0.0053 16.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain AAA_8 PF12780.7 RLN78111.1 - 3.1e-90 302.0 0.0 7e-90 300.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 RLN78111.1 - 3.4e-79 266.3 0.0 7.8e-79 265.1 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 RLN78111.1 - 4.8e-74 248.2 0.2 4.8e-74 248.2 0.2 2.6 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_6 PF12774.7 RLN78111.1 - 9.1e-71 238.5 0.1 1.5e-69 234.5 0.0 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region MT PF12777.7 RLN78111.1 - 2.2e-68 230.9 14.1 4.4e-68 229.8 14.1 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 RLN78111.1 - 2.7e-61 206.2 0.1 9.2e-45 152.4 0.0 4.2 3 1 1 4 4 4 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RLN78111.1 - 3.1e-49 166.9 0.1 2.1e-47 161.0 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RLN78111.1 - 7.8e-38 129.2 0.1 5.1e-34 116.9 0.0 3.1 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 RLN78111.1 - 3.7e-22 78.4 0.1 1.4e-21 76.5 0.1 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 RLN78111.1 - 7.5e-20 71.3 1.3 4.3e-11 43.0 0.0 6.4 5 1 0 5 5 5 2 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 RLN78111.1 - 4e-16 59.3 0.3 1.6e-15 57.3 0.3 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_19 PF13245.6 RLN78111.1 - 4.8e-06 27.0 1.7 0.059 13.7 0.0 3.8 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 RLN78111.1 - 6.6e-06 26.4 7.1 0.02 15.2 0.0 5.4 6 0 0 6 6 5 2 AAA domain AAA_33 PF13671.6 RLN78111.1 - 8.7e-05 22.7 1.0 2.4 8.3 0.0 4.0 4 0 0 4 4 3 1 AAA domain TrwB_AAD_bind PF10412.9 RLN78111.1 - 0.00019 20.5 0.0 0.32 9.9 0.1 2.6 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 RLN78111.1 - 0.00027 20.7 2.4 0.31 10.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 RLN78111.1 - 0.00065 19.4 0.1 0.58 9.8 0.0 3.7 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_18 PF13238.6 RLN78111.1 - 0.003 18.1 6.5 0.025 15.1 0.0 4.5 5 0 0 5 5 3 1 AAA domain FtsK_SpoIIIE PF01580.18 RLN78111.1 - 0.0038 16.6 0.4 17 4.6 0.0 3.4 3 0 0 3 3 3 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 RLN78111.1 - 0.004 17.5 0.2 2.7 8.4 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.6 RLN78111.1 - 0.005 17.2 9.3 0.69 10.3 0.0 5.5 7 0 0 7 7 4 1 AAA ATPase domain TsaE PF02367.17 RLN78111.1 - 0.013 15.5 0.7 0.42 10.6 0.1 3.0 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 RLN78111.1 - 0.015 14.7 0.1 3 7.2 0.0 3.3 3 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 RLN78111.1 - 0.027 14.3 0.2 0.62 9.8 0.0 2.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 RLN78111.1 - 0.029 14.3 0.1 8.7 6.2 0.0 3.4 3 0 0 3 3 3 0 NACHT domain AAA PF00004.29 RLN78111.1 - 0.037 14.4 6.8 6.5 7.2 0.0 4.5 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 RLN78111.1 - 0.038 13.9 0.9 2.8 7.8 0.0 2.6 2 0 0 2 2 2 0 NTPase IstB_IS21 PF01695.17 RLN78111.1 - 0.04 13.7 0.2 8.7 6.0 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_28 PF13521.6 RLN78111.1 - 0.042 14.1 0.0 0.66 10.2 0.0 3.1 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 RLN78111.1 - 0.047 13.9 0.1 3.6 7.8 0.1 3.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Sigma54_activ_2 PF14532.6 RLN78111.1 - 0.078 13.1 0.0 1.3 9.1 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 RLN78111.1 - 0.12 12.3 0.0 0.12 12.3 0.0 3.9 6 0 0 6 6 3 0 ATPase domain predominantly from Archaea DUF1672 PF07901.11 RLN78111.1 - 0.16 11.2 3.1 0.3 10.4 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) AAA_17 PF13207.6 RLN78111.1 - 0.43 11.0 2.2 1.4 9.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 RLN78111.1 - 0.45 10.2 9.7 10 5.8 0.1 3.7 3 0 0 3 3 3 0 AAA domain MPS2 PF17060.5 RLN78111.1 - 1.1 8.4 6.7 0.15 11.3 0.8 2.2 2 0 0 2 2 2 0 Monopolar spindle protein 2 cobW PF02492.19 RLN78111.1 - 1.7 8.2 4.7 9.2 5.8 0.0 3.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 RLN78111.1 - 1.8 7.7 6.0 1.2 8.3 0.0 2.8 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) Anoctamin PF04547.12 RLN78126.1 - 4e-70 236.9 8.3 5e-70 236.6 8.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF2207 PF09972.9 RLN78126.1 - 0.0064 15.3 0.8 0.1 11.4 0.0 2.2 2 0 0 2 2 2 2 Predicted membrane protein (DUF2207) Lyase_aromatic PF00221.19 RLN78144.1 - 1.5e-188 627.2 3.5 2.8e-188 626.3 3.5 1.4 1 1 0 1 1 1 1 Aromatic amino acid lyase DUF3458_C PF17432.2 RLN78145.1 - 9.9e-22 77.7 0.2 1.9e-21 76.8 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Bac_RepA_C PF18008.1 RLN78145.1 - 0.1 12.9 0.2 17 5.9 0.0 2.3 2 0 0 2 2 2 0 Replication initiator protein A C-terminal domain SDA1 PF05285.12 RLN78147.1 - 1.7e-05 24.4 5.1 2.1e-05 24.1 5.1 1.3 1 0 0 1 1 1 1 SDA1 DUF2052 PF09747.9 RLN78147.1 - 0.00065 19.9 9.2 0.0013 18.9 9.2 1.5 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) NOA36 PF06524.12 RLN78147.1 - 0.002 17.5 11.2 0.0033 16.8 11.2 1.3 1 0 0 1 1 1 1 NOA36 protein RR_TM4-6 PF06459.12 RLN78147.1 - 0.0036 17.2 6.1 0.0036 17.2 6.1 1.6 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 LBR_tudor PF09465.10 RLN78147.1 - 0.0057 16.4 0.2 0.81 9.5 0.1 2.7 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain eIF-3c_N PF05470.12 RLN78147.1 - 0.0092 14.3 2.4 0.011 14.1 2.4 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nop14 PF04147.12 RLN78147.1 - 0.034 12.4 16.0 0.048 11.9 16.0 1.1 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.13 RLN78147.1 - 0.07 13.4 8.2 0.12 12.6 8.2 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Mpp10 PF04006.12 RLN78147.1 - 0.077 11.4 17.2 0.11 10.9 17.2 1.2 1 0 0 1 1 1 0 Mpp10 protein Connexin PF00029.19 RLN78147.1 - 0.1 12.3 2.5 0.18 11.6 2.5 1.4 1 0 0 1 1 1 0 Connexin RNA_pol_3_Rpc31 PF11705.8 RLN78147.1 - 0.1 12.8 17.7 0.22 11.8 17.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PTPRCAP PF15713.5 RLN78147.1 - 0.15 12.4 17.4 0.34 11.2 17.4 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DNA_pol_phi PF04931.13 RLN78147.1 - 0.19 9.8 21.9 0.26 9.3 21.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Gly-rich_Ago1 PF12764.7 RLN78147.1 - 0.19 12.5 3.8 1.2 10.0 3.8 2.2 1 1 0 1 1 1 0 Glycine-rich region of argonaut RPA43_OB PF17875.1 RLN78147.1 - 0.31 11.7 4.7 0.7 10.5 4.7 1.7 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I TLP-20 PF06088.11 RLN78147.1 - 0.37 10.7 3.5 0.73 9.7 3.5 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) RXT2_N PF08595.11 RLN78147.1 - 0.39 10.7 10.4 0.31 11.1 8.6 1.8 2 0 0 2 2 1 0 RXT2-like, N-terminal FAM176 PF14851.6 RLN78147.1 - 0.57 9.8 10.5 1.5 8.5 10.5 1.8 1 0 0 1 1 1 0 FAM176 family DUF5523 PF17661.1 RLN78147.1 - 0.6 9.7 17.0 1.1 8.9 17.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) PPP4R2 PF09184.11 RLN78147.1 - 0.69 9.4 18.9 0.072 12.7 14.6 1.5 2 0 0 2 2 1 0 PPP4R2 RRN3 PF05327.11 RLN78147.1 - 1.3 7.5 8.5 1.8 7.0 8.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 RLN78147.1 - 1.4 8.2 17.1 2.3 7.5 17.2 1.4 1 1 0 1 1 1 0 BUD22 CDC45 PF02724.14 RLN78147.1 - 1.8 6.7 15.0 2.6 6.2 15.0 1.2 1 0 0 1 1 1 0 CDC45-like protein TFB6 PF17110.5 RLN78147.1 - 3.5 7.4 9.2 6.7 6.4 9.2 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF719 PF05334.13 RLN78147.1 - 3.6 7.7 11.4 0.31 11.2 4.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF719) RPN2_C PF18004.1 RLN78147.1 - 3.9 7.4 13.9 0.77 9.7 10.2 1.7 2 0 0 2 2 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain BSP_II PF05432.11 RLN78147.1 - 4.1 7.0 29.3 0.022 14.5 19.9 1.9 3 0 0 3 3 2 0 Bone sialoprotein II (BSP-II) PI3K_1B_p101 PF10486.9 RLN78147.1 - 4.1 5.1 7.0 8.4 4.0 7.0 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit MRNIP PF15749.5 RLN78147.1 - 4.5 8.0 6.9 11 6.8 6.9 1.7 1 0 0 1 1 1 0 MRN-interacting protein CobT PF06213.12 RLN78147.1 - 4.6 6.6 21.5 7.3 5.9 21.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT HNF-1_N PF04814.13 RLN78147.1 - 6 7.4 13.7 20 5.7 7.7 2.2 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus DUF1738 PF08401.11 RLN78147.1 - 7.1 6.7 6.6 18 5.4 6.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1738) Presenilin PF01080.17 RLN78147.1 - 7.7 5.2 8.5 0.36 9.5 3.3 1.4 2 0 0 2 2 2 0 Presenilin Nop53 PF07767.11 RLN78147.1 - 8.4 5.7 19.8 18 4.6 19.8 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DDE_Tnp_IS1 PF03400.13 RLN78149.1 - 1.3 9.4 5.7 9 6.6 0.7 2.1 2 0 0 2 2 2 0 IS1 transposase COG5 PF10392.9 RLN78150.1 - 4.1e-12 46.4 0.8 4.1e-12 46.4 0.8 2.0 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 RLN78150.1 - 6.6e-05 22.8 1.8 0.00017 21.5 1.8 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Zw10 PF06248.13 RLN78150.1 - 0.0026 16.4 1.7 0.0054 15.4 1.7 1.5 1 1 0 1 1 1 1 Centromere/kinetochore Zw10 Hrs_helical PF12210.8 RLN78150.1 - 0.016 15.7 3.1 0.02 15.4 1.3 2.1 2 0 0 2 2 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate YscO PF07321.12 RLN78150.1 - 0.02 14.9 0.3 0.082 12.9 0.3 2.0 1 0 0 1 1 1 0 Type III secretion protein YscO BLOC1_2 PF10046.9 RLN78150.1 - 0.072 13.4 0.1 0.96 9.8 0.0 3.0 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 RLN78150.1 - 0.12 12.6 0.1 0.34 11.1 0.1 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.11 RLN78150.1 - 0.57 10.8 3.4 1.4 9.5 0.9 2.8 3 0 0 3 3 3 0 Syntaxin 6, N-terminal COG2 PF06148.11 RLN78150.1 - 0.85 9.7 6.7 0.27 11.3 2.4 2.4 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Cob_adeno_trans PF01923.18 RLN78150.1 - 2.2 8.4 4.9 1.2 9.2 1.2 2.5 2 1 0 2 2 2 0 Cobalamin adenosyltransferase ATG16 PF08614.11 RLN78150.1 - 2.3 8.4 7.0 0.17 12.1 0.7 2.4 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 RLN78150.1 - 2.9 8.6 6.4 6 7.6 1.9 3.4 2 1 1 3 3 3 0 SlyX WW PF00397.26 RLN78151.1 - 2.1e-07 30.9 1.6 4e-07 30.0 1.6 1.4 1 0 0 1 1 1 1 WW domain IQ PF00612.27 RLN78152.1 - 0.00039 20.0 24.1 0.0019 17.8 1.0 5.2 4 0 0 4 4 4 3 IQ calmodulin-binding motif PMAIP1 PF15150.6 RLN78152.1 - 0.091 12.6 0.2 0.23 11.4 0.2 1.7 1 0 0 1 1 1 0 Phorbol-12-myristate-13-acetate-induced Myosin_head PF00063.21 RLN78153.1 - 7.9e-225 748.1 2.1 1.3e-224 747.4 2.1 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) ProQ PF04352.13 RLN78153.1 - 0.0049 16.7 0.0 0.018 14.9 0.0 2.0 1 0 0 1 1 1 1 ProQ/FINO family AAA_22 PF13401.6 RLN78153.1 - 0.031 14.5 0.0 0.23 11.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 RLN78153.1 - 0.046 14.1 0.0 0.22 11.9 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain Rootletin PF15035.6 RLN78153.1 - 0.074 13.1 16.8 0.18 11.8 16.8 1.6 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion FAM76 PF16046.5 RLN78153.1 - 0.078 12.3 11.0 0.16 11.3 11.0 1.4 1 0 0 1 1 1 0 FAM76 protein AAA_18 PF13238.6 RLN78153.1 - 0.2 12.2 1.6 0.35 11.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain Tcell_CD4_C PF12104.8 RLN78153.1 - 0.28 11.2 2.8 7.6 6.6 2.2 2.7 2 0 0 2 2 2 0 T cell CD4 receptor C terminal region ZapB PF06005.12 RLN78153.1 - 0.52 10.8 14.1 2 8.9 4.8 3.3 2 0 0 2 2 2 0 Cell division protein ZapB Rad1 PF02144.16 RLN78154.1 - 2.5e-37 128.5 0.0 7.2e-21 74.5 0.0 2.0 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Nup192 PF11894.8 RLN78173.1 - 3.5e-23 80.8 0.1 7.7e-14 49.9 0.4 2.2 2 0 0 2 2 2 2 Nuclear pore complex scaffold, nucleoporins 186/192/205 Ephrin_rec_like PF07699.13 RLN78174.1 - 5.1e-15 55.0 27.3 4.5e-07 29.5 1.4 4.9 2 1 3 5 5 5 4 Putative ephrin-receptor like LapA_dom PF06305.11 RLN78174.1 - 0.31 10.9 1.5 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Vps54_N PF10475.9 RLN78175.1 - 0.013 14.8 9.1 0.5 9.6 0.4 2.3 2 1 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Sec20 PF03908.13 RLN78175.1 - 1.2 9.1 8.6 6 6.9 3.3 2.9 2 1 1 3 3 3 0 Sec20 E1-E2_ATPase PF00122.20 RLN78176.1 - 1.2e-33 116.1 0.0 1.2e-33 116.1 0.0 2.8 3 1 1 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 RLN78176.1 - 9.2e-08 32.6 0.0 2.5e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RLN78176.1 - 0.00025 20.7 0.0 0.00068 19.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 RLN78176.1 - 0.0012 18.8 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Intein_splicing PF14890.6 RLN78176.1 - 0.17 11.8 0.0 0.36 10.8 0.0 1.5 1 1 0 1 1 1 0 Intein splicing domain Mito_carr PF00153.27 RLN78198.1 - 5.7e-59 196.1 0.1 3.4e-22 78.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ax_dynein_light PF10211.9 RLN78199.1 - 1.3e-41 142.6 2.5 1.7e-41 142.2 2.5 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain PspA_IM30 PF04012.12 RLN78199.1 - 0.066 12.8 1.6 0.35 10.4 1.6 1.9 1 1 0 1 1 1 0 PspA/IM30 family Med21 PF11221.8 RLN78199.1 - 0.11 12.8 4.6 1.1 9.4 0.5 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Spc24 PF08286.11 RLN78199.1 - 0.2 11.9 0.3 8 6.8 0.0 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TPD PF14811.6 RLN78200.1 - 1.3e-29 102.8 0.0 2.4e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif PPR_2 PF13041.6 RLN78200.1 - 5.2e-08 33.0 0.1 0.24 11.6 0.0 4.6 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.6 RLN78200.1 - 1.9e-05 24.7 0.0 0.05 13.7 0.0 3.5 2 1 1 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 RLN78200.1 - 0.027 13.9 0.0 0.067 12.5 0.0 1.7 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 RLN78200.1 - 0.11 12.8 0.9 77 3.9 0.0 4.2 4 0 0 4 4 4 0 PPR repeat DUF916 PF06030.12 RLN78200.1 - 0.97 9.5 4.3 2.1 8.4 4.3 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) Cyclin PF08613.11 RLN78201.1 - 3.6e-09 37.2 0.0 6.1e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 RLN78201.1 - 3.8e-08 33.1 0.2 7e-08 32.3 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain TAP42 PF04177.12 RLN78202.1 - 2.8e-56 191.0 24.9 2.7e-35 122.0 9.8 2.0 1 1 1 2 2 2 2 TAP42-like family COX7a PF02238.15 RLN78203.1 - 0.00036 20.9 0.0 0.00047 20.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Oxidored_FMN PF00724.20 RLN78204.1 - 4.7e-86 289.2 0.0 5.3e-86 289.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RNase_H PF00075.24 RLN78219.1 - 1.3e-27 96.7 0.3 7.8e-24 84.5 0.0 2.2 1 1 1 2 2 2 2 RNase H Cauli_VI PF01693.16 RLN78219.1 - 6.2e-07 29.6 1.1 5.9e-06 26.5 1.9 2.2 2 0 0 2 2 2 1 Caulimovirus viroplasmin CALM_bind PF16025.5 RLN78222.1 - 0.9 10.0 7.1 18 5.9 7.1 2.4 1 1 0 1 1 1 0 Calcium-dependent calmodulin binding Ank_2 PF12796.7 RLN78223.1 - 1.7e-29 102.3 9.6 1.4e-07 32.0 0.0 4.8 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN78223.1 - 4.4e-23 81.3 4.1 6.5e-06 26.6 0.0 6.6 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN78223.1 - 1.2e-19 70.1 8.2 0.015 15.6 0.0 9.3 6 4 3 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN78223.1 - 3.5e-14 51.5 1.0 17 6.4 0.0 9.0 8 1 1 9 9 9 2 Ankyrin repeat Ank PF00023.30 RLN78223.1 - 0.0015 18.9 0.5 85 3.9 0.0 6.2 4 3 0 4 4 4 0 Ankyrin repeat DUF5049 PF16468.5 RLN78223.1 - 0.0024 17.7 0.0 33 4.5 0.0 4.8 5 1 1 6 6 6 0 Domain of unknown function (DUF5049) Dimer_Tnp_hAT PF05699.14 RLN78223.1 - 0.093 12.5 0.2 2.9 7.8 0.0 3.4 4 1 0 4 4 4 0 hAT family C-terminal dimerisation region CALM_bind PF16025.5 RLN78224.1 - 0.17 12.4 0.8 0.45 11.0 0.8 1.8 1 1 0 1 1 1 0 Calcium-dependent calmodulin binding ATG16 PF08614.11 RLN78224.1 - 0.21 11.8 2.9 0.32 11.2 2.9 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Csm1_N PF18504.1 RLN78224.1 - 0.31 11.4 2.6 3.6 8.0 0.4 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain Ndc1_Nup PF09531.10 RLN78224.1 - 1.7 7.3 4.2 2.3 6.8 4.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4618 PF15397.6 RLN78225.1 - 0.34 10.3 7.0 0.51 9.7 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Pkinase PF00069.25 RLN78227.1 - 7.1e-14 51.8 0.0 1.5e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN78227.1 - 3.1e-07 29.9 0.0 3.7e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase SPATIAL PF15256.6 RLN78227.1 - 1.8 8.8 3.6 3.2 8.0 3.6 1.4 1 0 0 1 1 1 0 SPATIAL Cu-oxidase_2 PF07731.14 RLN78286.1 - 1.6e-13 50.6 1.2 1.2e-12 47.8 1.2 2.3 1 1 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN78286.1 - 4.4e-13 49.3 1.4 1.3e-07 31.6 0.1 3.6 3 0 0 3 3 3 3 Multicopper oxidase ABC_tran PF00005.27 RLN78327.1 - 4.8e-51 172.9 0.0 7.4e-26 91.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN78327.1 - 4.4e-14 53.0 5.8 0.00057 19.8 0.1 4.1 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 RLN78327.1 - 3.3e-10 39.9 8.4 8.2e-09 35.4 1.8 2.7 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 RLN78327.1 - 1.2e-07 31.4 8.6 0.19 11.2 0.3 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain NB-ARC PF00931.22 RLN78327.1 - 2.8e-07 30.0 0.0 0.021 14.0 0.0 3.0 2 1 0 2 2 2 2 NB-ARC domain AAA_29 PF13555.6 RLN78327.1 - 3.9e-06 26.5 1.1 0.037 13.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN78327.1 - 1.5e-05 25.5 0.1 0.0084 16.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 RLN78327.1 - 5.6e-05 23.7 0.6 0.044 14.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 RLN78327.1 - 0.00012 22.2 0.6 0.22 11.6 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 RLN78327.1 - 0.00013 22.2 0.3 0.2 11.9 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RLN78327.1 - 0.00031 21.3 10.2 0.012 16.1 0.1 2.9 4 0 0 4 4 2 2 AAA domain RsgA_GTPase PF03193.16 RLN78327.1 - 0.0012 18.8 0.3 1.7 8.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 RLN78327.1 - 0.0021 17.8 0.2 2.3 7.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 RLN78327.1 - 0.0024 18.1 1.0 7.5 6.9 0.0 4.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 RLN78327.1 - 0.0035 16.9 0.1 0.22 11.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_13 PF13166.6 RLN78327.1 - 0.0037 16.0 0.1 0.68 8.5 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 RLN78327.1 - 0.0041 17.2 0.1 0.9 9.6 0.0 3.1 3 1 1 4 4 3 1 AAA domain AAA_24 PF13479.6 RLN78327.1 - 0.0052 16.5 0.5 1.2 8.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain DLIC PF05783.11 RLN78327.1 - 0.0082 15.0 0.1 0.75 8.5 0.0 2.1 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) AAA_19 PF13245.6 RLN78327.1 - 0.011 16.0 0.1 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 RLN78327.1 - 0.013 15.6 0.3 1.1 9.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 RLN78327.1 - 0.016 15.7 2.3 2.3 8.6 0.1 3.1 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 RLN78327.1 - 0.037 13.9 0.0 10 6.0 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain FeoB_N PF02421.18 RLN78327.1 - 0.038 13.5 0.3 1.7 8.1 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B YonK PF09642.10 RLN78327.1 - 0.05 13.8 0.0 0.32 11.2 0.0 2.4 2 0 0 2 2 2 0 YonK protein AAA_15 PF13175.6 RLN78327.1 - 0.053 13.2 0.2 6.7 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 RLN78327.1 - 0.055 12.5 0.1 3 6.8 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase_2 PF01637.18 RLN78327.1 - 0.064 13.2 0.1 0.76 9.6 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 RLN78327.1 - 0.071 12.4 1.6 4.4 6.6 0.0 2.5 2 0 0 2 2 2 0 KaiC Roc PF08477.13 RLN78327.1 - 0.072 13.3 0.6 13 6.0 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 RLN78327.1 - 0.074 12.6 0.4 6.7 6.3 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 RLN78327.1 - 0.088 12.6 0.4 3.8 7.2 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 RLN78327.1 - 0.092 11.7 0.3 1.7 7.5 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 RLN78327.1 - 0.11 12.8 2.3 6.2 7.1 0.0 3.3 3 1 0 3 3 2 0 AAA domain Dynamin_N PF00350.23 RLN78327.1 - 0.12 12.4 0.9 11 6.1 0.1 2.8 2 1 0 2 2 2 0 Dynamin family RNA_helicase PF00910.22 RLN78327.1 - 0.15 12.5 0.3 11 6.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 RLN78327.1 - 0.36 10.7 1.6 7.5 6.4 0.1 2.5 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 RLN78327.1 - 0.5 10.3 4.0 7.6 6.4 0.1 2.7 3 0 0 3 3 2 0 NACHT domain GFO_IDH_MocA PF01408.22 RLN78328.1 - 1.3e-13 51.8 0.0 2.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 RLN78328.1 - 8.1e-06 25.8 0.0 2.1e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Gp_dh_N PF00044.24 RLN78328.1 - 0.0022 18.3 0.0 0.085 13.2 0.0 2.6 3 0 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 RLN78328.1 - 0.077 13.1 0.1 0.2 11.8 0.1 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Acetyltransf_1 PF00583.25 RLN78330.1 - 2.6e-14 53.4 0.0 3.6e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RLN78330.1 - 3.1e-06 27.5 0.0 4.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RLN78330.1 - 3.9e-06 26.8 0.0 6.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN78330.1 - 1.6e-05 24.8 0.0 3.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 RLN78330.1 - 0.049 13.8 0.0 0.081 13.1 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PanZ PF12568.8 RLN78330.1 - 0.12 12.1 0.1 0.44 10.3 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ Coprogen_oxidas PF01218.18 RLN78331.1 - 9.3e-136 451.3 0.0 1.1e-135 451.1 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase LIN52 PF10044.9 RLN78331.1 - 0.037 14.7 0.0 0.088 13.5 0.0 1.6 1 0 0 1 1 1 0 Retinal tissue protein Coprogen_oxidas PF01218.18 RLN78332.1 - 1.7e-131 437.4 0.0 1.9e-131 437.2 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Pkinase PF00069.25 RLN78334.1 - 2.2e-48 164.9 0.0 2.9e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN78334.1 - 2.5e-44 151.5 0.0 3.3e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RLN78334.1 - 0.0081 15.1 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain DUF3446 PF11928.8 RLN78334.1 - 3.6 7.9 11.9 4.9 7.5 3.5 3.2 3 0 0 3 3 3 0 Early growth response N-terminal domain Pkinase PF00069.25 RLN78335.1 - 2.1e-49 168.3 0.0 3.8e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN78335.1 - 1.5e-47 162.1 0.0 2.1e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RLN78335.1 - 8.7e-05 21.6 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RLN78335.1 - 0.013 14.9 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN78335.1 - 0.032 14.1 0.4 0.1 12.5 0.2 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF2561 PF10812.8 RLN78335.1 - 0.071 13.1 0.2 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) Carb_anhydrase PF00194.21 RLN78336.1 - 2.4e-40 138.7 0.0 3.4e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Tetraspanin PF00335.20 RLN78339.1 - 0.15 11.8 2.1 0.2 11.4 2.1 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF4131 PF13567.6 RLN78339.1 - 9.7 5.8 8.4 4.3e+02 0.4 8.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1510 PF07423.11 RLN78340.1 - 0.021 14.9 0.1 0.042 14.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) Patatin PF01734.22 RLN78341.1 - 3.8e-14 53.4 0.2 2.1e-12 47.6 0.0 2.7 2 1 0 2 2 2 1 Patatin-like phospholipase DUF3592 PF12158.8 RLN78341.1 - 0.069 13.2 0.2 0.79 9.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) LRR_4 PF12799.7 RLN78342.1 - 6.5e-27 93.2 16.0 0.00025 21.4 0.0 11.6 9 3 4 13 13 13 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN78342.1 - 1.2e-07 31.4 19.4 0.01 15.6 0.4 8.0 6 2 1 7 7 7 4 Leucine rich repeat LRR_9 PF14580.6 RLN78342.1 - 0.0062 16.1 10.8 0.47 9.9 0.8 5.0 3 2 1 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 RLN78342.1 - 0.0095 15.9 7.2 1.8 8.8 0.0 6.3 8 0 0 8 8 8 1 Leucine Rich repeat PX PF00787.24 RLN78343.1 - 3e-06 27.2 0.0 4.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 PX domain Transferase PF02458.15 RLN78344.1 - 8.8e-28 97.1 0.0 1.1e-27 96.8 0.0 1.0 1 0 0 1 1 1 1 Transferase family YjgF_endoribonc PF14588.6 RLN78345.1 - 2e-26 92.9 0.3 5.6e-23 81.7 0.1 2.0 1 1 1 2 2 2 2 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 RLN78345.1 - 4.6e-15 55.7 0.1 3e-13 49.8 0.0 2.1 2 0 0 2 2 2 2 Endoribonuclease L-PSP ABC2_membrane PF01061.24 RLN78346.1 - 1.7e-33 115.8 12.3 2.3e-33 115.4 12.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN78346.1 - 7.3e-23 81.6 0.0 1.2e-22 80.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN78346.1 - 6e-07 29.6 0.0 0.01 15.7 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN78346.1 - 3.9e-05 24.1 0.1 9.4e-05 22.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 RLN78346.1 - 0.00036 19.8 6.5 0.00036 19.8 6.5 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 RLN78346.1 - 0.0019 18.1 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN78346.1 - 0.006 16.3 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 RLN78346.1 - 0.044 13.2 0.1 3.2 7.1 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 RLN78346.1 - 0.06 12.9 0.2 0.22 11.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 RLN78346.1 - 0.15 12.4 0.0 0.43 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 RLN78346.1 - 0.16 12.0 0.3 0.35 10.9 0.1 1.6 2 0 0 2 2 2 0 Dynamin family MMR_HSR1 PF01926.23 RLN78346.1 - 0.22 11.6 0.1 0.49 10.5 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 RLN78346.1 - 0.25 11.8 0.0 0.41 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Bact_lectin PF18483.1 RLN78347.1 - 2.1e-15 57.3 0.0 4.1e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 RLN78347.1 - 1.4e-07 31.4 0.0 3.3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Legume lectin domain TFR_dimer PF04253.15 RLN78348.1 - 0.041 14.0 2.1 0.061 13.4 0.1 2.2 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain SlyX PF04102.12 RLN78348.1 - 0.13 12.9 0.5 0.13 12.9 0.5 3.8 3 1 0 3 3 3 0 SlyX FlaC_arch PF05377.11 RLN78348.1 - 0.17 12.3 7.8 0.16 12.4 1.7 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 RLN78348.1 - 3.5 7.7 14.9 12 6.0 8.7 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF724 PF05266.14 RLN78348.1 - 6.6 6.5 11.8 10 5.9 5.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF2730 PF10805.8 RLN78349.1 - 0.0028 17.7 0.6 2.1 8.5 0.0 3.9 3 1 1 4 4 4 1 Protein of unknown function (DUF2730) DUF4795 PF16043.5 RLN78349.1 - 0.032 13.9 3.0 6.5 6.3 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) CLZ PF16526.5 RLN78349.1 - 0.19 12.1 6.1 4.6 7.7 0.2 3.6 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BST2 PF16716.5 RLN78349.1 - 0.7 10.5 6.8 0.31 11.7 1.8 2.7 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 FAM184 PF15665.5 RLN78349.1 - 3.1 7.5 9.2 0.49 10.1 2.7 2.4 3 0 0 3 3 3 0 Family with sequence similarity 184, A and B DUF4200 PF13863.6 RLN78349.1 - 3.8 7.9 7.5 9.7 6.6 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) OmpH PF03938.14 RLN78349.1 - 4.4 7.7 9.9 0.46 10.8 4.4 2.0 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) COX16 PF14138.6 RLN78351.1 - 0.43 11.1 1.7 2 9.0 1.7 2.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Carb_anhydrase PF00194.21 RLN78352.1 - 6.6e-29 101.2 0.0 1.1e-28 100.5 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 RLN78353.1 - 1.9e-36 125.9 0.1 4.9e-25 88.5 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic-type carbonic anhydrase HCV_NS2 PF01538.18 RLN78353.1 - 0.07 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 Ax_dynein_light PF10211.9 RLN78389.1 - 1.9e-29 103.0 6.4 2.5e-29 102.6 6.4 1.2 1 0 0 1 1 1 1 Axonemal dynein light chain CENP-Q PF13094.6 RLN78389.1 - 0.1 12.8 6.6 0.18 12.0 6.6 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CENP-H PF05837.12 RLN78389.1 - 0.54 10.7 7.7 0.87 10.0 6.8 1.8 1 1 0 2 2 2 0 Centromere protein H (CENP-H) APG6_N PF17675.1 RLN78389.1 - 5.6 7.5 14.1 0.84 10.2 8.7 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region Cyclin PF08613.11 RLN78390.1 - 5.4e-09 36.6 0.0 8.6e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 RLN78390.1 - 3.9e-08 33.1 0.2 7.1e-08 32.2 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain CARMIL_C PF16000.5 RLN78390.1 - 0.036 13.7 0.4 0.057 13.1 0.4 1.2 1 0 0 1 1 1 0 CARMIL C-terminus TPD PF14811.6 RLN78391.1 - 3.8e-33 114.3 0.0 7e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif PPR_2 PF13041.6 RLN78391.1 - 6.7e-08 32.6 0.1 0.26 11.5 0.0 4.6 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.6 RLN78391.1 - 2.2e-05 24.4 0.0 0.056 13.5 0.0 3.6 2 1 1 3 3 3 2 Pentatricopeptide repeat domain COX7a PF02238.15 RLN78391.1 - 0.013 15.9 0.1 0.033 14.6 0.0 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII PPR_long PF17177.4 RLN78391.1 - 0.027 13.8 0.0 0.15 11.4 0.0 1.8 1 1 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 RLN78391.1 - 0.11 12.8 0.9 84 3.8 0.0 4.4 4 0 0 4 4 4 0 PPR repeat Myc_N PF01056.18 RLN78392.1 - 0.0023 17.9 0.3 0.0029 17.6 0.3 1.0 1 0 0 1 1 1 1 Myc amino-terminal region YfhO PF09586.10 RLN78392.1 - 0.33 9.1 0.0 0.41 8.8 0.0 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO GPCR_chapero_1 PF11904.8 RLN78393.1 - 9.9e-31 107.3 12.4 1.7e-20 73.7 2.2 3.3 2 2 0 2 2 2 2 GPCR-chaperone Ank PF00023.30 RLN78393.1 - 3e-05 24.3 0.1 0.019 15.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 RLN78393.1 - 0.00031 21.3 0.1 0.0021 18.6 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN78393.1 - 0.0081 16.7 0.7 15 6.3 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN78393.1 - 0.013 15.9 0.1 0.99 10.2 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat Mito_carr PF00153.27 RLN78394.1 - 8.8e-59 195.5 0.0 3.7e-22 78.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Oxidored_FMN PF00724.20 RLN78395.1 - 8.6e-86 288.3 0.0 9.8e-86 288.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF4643 PF15485.6 RLN78396.1 - 7.3 6.3 12.3 0.12 12.2 3.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4643) MRC1 PF09444.10 RLN78397.1 - 4.1e-09 37.1 15.0 4.1e-09 37.1 15.0 6.9 3 1 0 5 5 5 1 MRC1-like domain TAP42 PF04177.12 RLN78399.1 - 9.8e-56 189.2 25.0 8.3e-35 120.4 9.7 2.0 1 1 1 2 2 2 2 TAP42-like family GAF PF01590.26 RLN78400.1 - 1.2e-05 26.0 1.5 0.0012 19.5 0.2 3.5 3 2 0 3 3 3 1 GAF domain FYVE PF01363.21 RLN78400.1 - 0.012 15.8 8.4 0.031 14.4 8.4 1.8 1 0 0 1 1 1 0 FYVE zinc finger Fer4_9 PF13187.6 RLN78400.1 - 0.98 9.6 10.9 3.4 7.9 10.9 2.0 1 0 0 1 1 1 0 4Fe-4S dicluster domain Rad50_zn_hook PF04423.14 RLN78400.1 - 1.9 8.4 3.7 5.4 6.9 1.2 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif PAS PF00989.25 RLN78412.1 - 5e-86 284.2 0.7 1.3e-19 70.3 0.0 5.3 5 0 0 5 5 5 5 PAS fold PAS_4 PF08448.10 RLN78412.1 - 3e-51 172.3 0.0 1.5e-12 47.7 0.0 5.7 5 0 0 5 5 5 5 PAS fold PAS_9 PF13426.7 RLN78412.1 - 6.3e-47 158.1 5.4 1e-10 41.8 0.1 5.8 6 0 0 6 6 6 5 PAS domain PAS_3 PF08447.12 RLN78412.1 - 1.1e-27 96.2 0.0 7.3e-07 29.4 0.0 5.4 5 0 0 5 5 5 4 PAS fold HATPase_c PF02518.26 RLN78412.1 - 1.3e-27 96.5 0.0 5.3e-27 94.5 0.0 2.1 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 RLN78412.1 - 4.9e-21 75.0 0.0 1.2e-20 73.7 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 RLN78412.1 - 5.8e-17 61.5 0.4 2.8e-16 59.3 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 RLN78412.1 - 7.9e-15 54.5 0.1 0.031 14.3 0.0 4.6 4 0 0 4 4 4 4 PAS domain PAS_10 PF13596.6 RLN78412.1 - 1.3e-08 35.4 0.4 0.056 14.0 0.0 4.1 5 0 0 5 5 5 3 PAS domain Hpt PF01627.23 RLN78412.1 - 1.7e-06 28.1 0.2 5.2e-06 26.6 0.2 1.9 1 0 0 1 1 1 1 Hpt domain PAS_7 PF12860.7 RLN78412.1 - 5.9e-06 26.4 3.1 0.13 12.4 0.1 5.5 5 2 0 5 5 5 1 PAS fold DUF3215 PF11503.8 RLN78412.1 - 8.9 6.2 5.8 30 4.6 0.1 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF3215) Arm PF00514.23 RLN78413.1 - 8.8e-191 613.1 226.9 2.4e-09 36.9 0.2 65.5 72 0 0 72 72 71 41 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 RLN78413.1 - 4.1e-40 137.8 9.5 0.00097 18.7 0.1 18.0 5 2 13 19 19 19 12 Armadillo-like HEAT_2 PF13646.6 RLN78413.1 - 1.5e-32 111.9 160.1 0.051 14.0 0.4 32.2 13 10 20 38 38 38 18 HEAT repeats KAP PF05804.12 RLN78413.1 - 9.7e-13 47.2 0.0 0.018 13.2 0.0 8.9 9 3 0 9 9 9 3 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 RLN78413.1 - 1.2e-10 41.2 11.9 0.21 10.8 0.1 12.5 9 5 2 11 11 11 3 V-ATPase subunit H V-ATPase_H_C PF11698.8 RLN78413.1 - 6e-09 36.0 0.1 4.3 7.5 0.0 10.3 11 1 1 12 12 12 1 V-ATPase subunit H RICTOR_V PF14668.6 RLN78413.1 - 7.3e-06 26.1 1.0 1.9 8.8 0.0 7.4 8 0 0 8 8 7 1 Rapamycin-insensitive companion of mTOR, domain 5 Atx10homo_assoc PF09759.9 RLN78413.1 - 1.5e-05 24.9 25.4 37 4.4 0.0 15.2 15 3 3 19 19 19 0 Spinocerebellar ataxia type 10 protein domain DGF-1_C PF11040.8 RLN78413.1 - 0.0062 16.5 0.7 6.1 6.9 0.0 4.4 4 0 0 4 4 3 1 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus HEAT_EZ PF13513.6 RLN78413.1 - 0.01 16.3 0.2 0.01 16.3 0.2 32.9 30 7 11 41 41 41 0 HEAT-like repeat UNC45-central PF11701.8 RLN78413.1 - 0.011 15.7 0.1 0.011 15.7 0.1 8.3 8 1 1 9 9 9 0 Myosin-binding striated muscle assembly central RICTOR_N PF14664.6 RLN78413.1 - 0.028 13.4 30.0 0.76 8.7 0.0 9.5 10 1 1 11 11 11 0 Rapamycin-insensitive companion of mTOR, N-term HEAT PF02985.22 RLN78413.1 - 0.053 13.8 0.1 0.053 13.8 0.1 33.5 40 0 0 40 40 38 0 HEAT repeat Nipped-B_C PF12830.7 RLN78413.1 - 0.084 12.8 2.2 4.4 7.2 0.0 4.7 4 0 0 4 4 4 0 Sister chromatid cohesion C-terminus Dickkopf_N PF04706.12 RLN78413.1 - 0.36 11.3 2.6 53 4.4 0.0 4.2 4 0 0 4 4 4 0 Dickkopf N-terminal cysteine-rich region Pkinase PF00069.25 RLN78414.1 - 7.3e-41 140.3 0.0 1.6e-34 119.5 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN78414.1 - 2.6e-21 76.1 0.0 1.4e-19 70.4 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 RLN78414.1 - 0.056 12.5 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 RLN78414.1 - 0.096 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Ank_2 PF12796.7 RLN78415.1 - 8.8e-08 32.6 0.0 0.0065 17.0 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN78415.1 - 2.4e-05 24.8 0.3 0.053 14.1 0.3 2.6 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN78415.1 - 2.6e-05 24.2 0.0 0.47 11.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 RLN78415.1 - 3.3e-05 24.1 0.7 1.6 9.3 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RLN78415.1 - 0.00017 21.8 0.1 1.2 9.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Spt20 PF12090.8 RLN78415.1 - 0.82 9.2 8.7 1.8 8.1 8.7 1.5 1 0 0 1 1 1 0 Spt20 family TERB2 PF15101.6 RLN78415.1 - 7.5 6.6 9.0 3.3 7.7 5.1 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 NDC10_II PF16787.5 RLN78429.1 - 1.5e-61 208.2 0.0 1.9e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 RLN78429.1 - 2.1e-19 69.6 0.0 4.2e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Peptidase_M74 PF03411.13 RLN78430.1 - 0.07 12.7 1.1 0.13 11.8 1.1 1.4 1 0 0 1 1 1 0 Penicillin-insensitive murein endopeptidase zf-C2H2_4 PF13894.6 RLN78430.1 - 0.075 13.9 12.3 10 7.3 2.0 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger FYDLN_acid PF09538.10 RLN78430.1 - 0.078 13.7 0.3 0.078 13.7 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DZR PF12773.7 RLN78430.1 - 0.27 11.3 1.7 0.63 10.1 1.7 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-Di19 PF05605.12 RLN78430.1 - 2.6 8.4 6.6 0.6 10.4 0.8 2.6 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding 5_nucleotid_C PF02872.18 RLN78448.1 - 1.2e-23 84.0 0.0 1.9e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 RLN78448.1 - 2.5e-05 24.9 0.0 4.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ASFV_J13L PF05568.11 RLN78449.1 - 0.02 14.6 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Nse4_C PF08743.10 RLN78450.1 - 1.6e-22 79.6 0.4 3.9e-22 78.3 0.0 1.9 2 0 0 2 2 2 1 Nse4 C-terminal DUF525 PF04379.14 RLN78454.1 - 1.5e-20 73.2 0.0 4.6e-20 71.6 0.0 1.8 2 0 0 2 2 2 1 ApaG domain Tox-HNH-EHHH PF15657.6 RLN78454.1 - 0.048 14.0 0.0 7.1 7.1 0.0 2.4 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxins ABC2_membrane PF01061.24 RLN78455.1 - 2.4e-67 226.4 65.9 2.7e-36 125.0 25.6 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN78455.1 - 3.2e-30 105.4 0.0 5.6e-14 52.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 RLN78455.1 - 8.3e-08 32.8 1.7 0.0011 19.4 0.1 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 RLN78455.1 - 8.4e-07 29.1 0.0 0.31 10.8 0.0 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN78455.1 - 1.3e-06 28.0 4.0 0.0083 15.8 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN78455.1 - 5e-06 26.5 0.8 0.096 12.6 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 RLN78455.1 - 4.2e-05 23.2 0.3 0.26 10.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RLN78455.1 - 0.0001 22.6 0.0 0.39 11.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN78455.1 - 0.00018 20.8 0.5 0.043 13.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.6 RLN78455.1 - 0.0035 17.9 0.3 1.4 9.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RLN78455.1 - 0.005 17.3 0.0 2.9 8.3 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RLN78455.1 - 0.0063 17.1 0.0 3.8 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 RLN78455.1 - 0.0076 16.2 0.1 1.7 8.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 RLN78455.1 - 0.009 15.8 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 RLN78455.1 - 0.015 15.4 0.3 1.8 8.7 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 RLN78455.1 - 0.018 14.9 2.5 3.2 7.6 0.2 2.7 2 0 0 2 2 2 0 NACHT domain PDR_CDR PF06422.12 RLN78455.1 - 0.019 14.8 0.0 0.019 14.8 0.0 3.1 3 1 0 3 3 3 0 CDR ABC transporter AAA_33 PF13671.6 RLN78455.1 - 0.028 14.6 0.1 5.1 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 RLN78455.1 - 0.037 13.4 0.5 13 5.1 0.0 3.2 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 RLN78455.1 - 0.065 12.8 1.3 2.1 7.9 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 RLN78455.1 - 0.092 12.5 0.1 8.2 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RLN78455.1 - 0.13 12.5 0.1 11 6.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 RLN78455.1 - 0.15 12.2 0.7 9.5 6.2 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Gelsolin PF00626.22 RLN78456.1 - 5.3e-53 176.8 0.0 5.2e-14 51.9 0.0 4.2 4 0 0 4 4 4 4 Gelsolin repeat Malic_M PF03949.15 RLN78457.1 - 2.9e-98 328.3 0.2 3.7e-98 327.9 0.2 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 RLN78457.1 - 4e-69 232.1 0.0 2.8e-68 229.3 0.0 2.1 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Shikimate_DH PF01488.20 RLN78457.1 - 0.15 12.1 0.3 2.4 8.2 0.3 2.2 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CAP PF00188.26 RLN78458.1 - 2e-09 38.4 0.6 3.8e-09 37.5 0.6 1.5 1 1 0 1 1 1 1 Cysteine-rich secretory protein family DSPn PF14671.6 RLN78471.1 - 8.5e-27 94.3 0.0 9.8e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half Skp1 PF01466.19 RLN78472.1 - 1.1e-21 76.7 0.2 1.8e-21 75.9 0.2 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 RLN78472.1 - 2.5e-19 69.2 0.1 4.9e-19 68.3 0.1 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain tRNA_U5-meth_tr PF05958.11 RLN78489.1 - 2.2e-11 43.4 0.0 3e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TALPID3 PF15324.6 RLN78489.1 - 0.11 10.1 0.0 0.13 9.9 0.0 1.0 1 0 0 1 1 1 0 Hedgehog signalling target LRR_6 PF13516.6 RLN78490.1 - 2.5e-09 36.4 1.3 0.62 10.3 0.0 6.1 6 0 0 6 6 6 3 Leucine Rich repeat LRR_8 PF13855.6 RLN78490.1 - 0.0097 15.7 0.0 10 6.0 0.0 3.6 3 1 0 3 3 3 1 Leucine rich repeat adh_short PF00106.25 RLN78491.1 - 3.1e-20 72.5 0.3 4.4e-15 55.7 0.1 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN78491.1 - 2.8e-13 50.0 0.6 7.7e-10 38.7 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN78491.1 - 0.0013 18.7 0.1 0.0083 16.0 0.0 2.0 2 0 0 2 2 2 1 KR domain HOASN PF14515.6 RLN78491.1 - 0.16 12.4 0.5 1.6 9.1 0.6 2.4 1 1 1 2 2 2 0 Haem-oxygenase-associated N-terminal helices Kinesin PF00225.23 RLN78492.1 - 1.6e-86 290.3 0.1 4.8e-86 288.7 0.1 1.6 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN78492.1 - 1.3e-19 70.6 0.0 1.4e-18 67.3 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding DUF3500 PF12006.8 RLN78492.1 - 0.054 13.0 1.6 0.085 12.3 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3500) OEP PF02321.18 RLN78492.1 - 0.58 9.9 10.3 3.8 7.3 1.1 3.7 3 0 0 3 3 3 0 Outer membrane efflux protein MRI PF15325.6 RLN78492.1 - 1.9 9.6 6.0 0.49 11.5 0.8 2.6 2 0 0 2 2 2 0 Modulator of retrovirus infection Fringe PF02434.16 RLN78493.1 - 3.9e-14 52.7 0.1 5.2e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.12 RLN78493.1 - 0.039 13.4 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF604 Galactosyl_T PF01762.21 RLN78493.1 - 0.17 11.7 0.0 0.38 10.6 0.0 1.6 2 0 0 2 2 2 0 Galactosyltransferase DUF2275 PF10039.9 RLN78494.1 - 0.11 12.5 3.6 1.4 9.0 0.1 2.5 2 1 0 2 2 2 0 Predicted integral membrane protein (DUF2275) DUF4418 PF14387.6 RLN78494.1 - 1.2 9.4 11.3 0.52 10.5 2.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4418) Tetraspanin PF00335.20 RLN78494.1 - 6.4 6.4 19.8 0.48 10.1 11.5 2.5 2 1 0 3 3 3 0 Tetraspanin family HUN PF08729.10 RLN78495.1 - 1.6e-10 40.8 5.5 3.2e-10 39.8 5.5 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Peptidase_M13_N PF05649.13 RLN78497.1 - 1.5e-73 248.8 0.0 1.9e-73 248.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 RLN78497.1 - 3.3e-65 219.5 0.1 3.2e-44 151.0 0.0 3.0 3 0 0 3 3 3 2 Peptidase family M13 ABC2_membrane PF01061.24 RLN78498.1 - 1.5e-65 220.5 62.1 2.9e-37 128.1 25.1 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN78498.1 - 3.5e-36 124.7 0.1 1e-17 64.9 0.0 2.2 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 RLN78498.1 - 5e-10 39.1 1.8 1.3e-07 31.4 0.0 3.3 3 0 0 3 3 3 1 CDR ABC transporter AAA_16 PF13191.6 RLN78498.1 - 3.1e-08 34.2 0.3 0.0051 17.2 0.2 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 RLN78498.1 - 1.5e-07 31.6 0.0 0.085 12.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN78498.1 - 1.9e-06 27.5 4.0 0.025 14.3 1.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN78498.1 - 3.5e-06 27.0 1.5 0.0097 15.8 0.4 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_25 PF13481.6 RLN78498.1 - 4.1e-05 23.3 0.1 0.35 10.4 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RLN78498.1 - 0.00017 22.2 0.4 0.3 11.6 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RLN78498.1 - 0.00019 21.7 0.1 0.61 10.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 RLN78498.1 - 0.00021 20.8 0.7 0.5 9.8 0.1 3.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 RLN78498.1 - 0.0018 18.0 0.5 1.5 8.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain PDR_assoc PF08370.11 RLN78498.1 - 0.003 17.3 0.2 0.015 15.1 0.1 4.3 5 0 0 5 5 3 2 Plant PDR ABC transporter associated MMR_HSR1 PF01926.23 RLN78498.1 - 0.0042 17.2 0.3 1.5 8.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.7 RLN78498.1 - 0.0055 15.9 45.0 0.0089 15.2 10.1 3.2 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA PF00004.29 RLN78498.1 - 0.0066 16.9 0.1 7 7.1 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RLN78498.1 - 0.0068 17.0 0.1 5.6 7.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RLN78498.1 - 0.0071 15.7 2.8 0.27 10.5 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 RLN78498.1 - 0.0076 16.2 1.8 2.5 8.0 0.1 2.6 2 0 0 2 2 2 2 NACHT domain cobW PF02492.19 RLN78498.1 - 0.024 14.3 0.9 2 8.0 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.9 RLN78498.1 - 0.026 13.3 0.3 0.54 9.0 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Ploopntkinase3 PF18751.1 RLN78498.1 - 0.028 14.3 0.3 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Rad17 PF03215.15 RLN78498.1 - 0.052 13.5 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_33 PF13671.6 RLN78498.1 - 0.061 13.5 0.1 6.2 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RLN78498.1 - 0.066 13.6 0.5 8.3 6.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 RLN78498.1 - 0.073 13.1 0.2 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 RLN78498.1 - 0.12 11.7 0.2 2.8 7.2 0.0 2.4 2 0 0 2 2 2 0 KaiC Roc PF08477.13 RLN78498.1 - 0.23 11.7 0.8 16 5.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 RLN78498.1 - 0.24 11.1 0.8 5.2 6.8 0.3 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 RLN78498.1 - 0.35 10.9 5.7 1.8 8.6 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain TsaE PF02367.17 RLN78498.1 - 0.67 10.0 2.1 3.5 7.7 0.3 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Kinesin PF00225.23 RLN78499.1 - 5.8e-83 278.6 2.9 5.3e-52 176.8 0.0 2.9 2 1 1 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 RLN78499.1 - 4.7e-25 88.3 0.0 1.2e-24 87.0 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 RLN78499.1 - 0.0002 21.6 0.0 0.0002 21.6 0.0 3.6 2 1 0 3 3 3 1 Kinesin-associated CheD PF03975.13 RLN78499.1 - 0.1 12.7 3.1 0.31 11.2 0.2 2.7 2 0 0 2 2 2 0 CheD chemotactic sensory transduction LRR_3 PF07725.12 RLN78499.1 - 0.14 12.0 0.1 0.47 10.4 0.1 2.0 2 0 0 2 2 2 0 Leucine Rich Repeat DUF3546 PF12066.8 RLN78500.1 - 7.3e-18 64.8 6.2 1.1e-17 64.2 6.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) DUF3283 PF11686.8 RLN78500.1 - 0.033 14.0 0.5 0.093 12.6 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3283) MARVEL PF01284.23 RLN78501.1 - 3.1e-06 27.3 9.7 4.6e-06 26.7 9.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain Gag_p6 PF08705.11 RLN78501.1 - 0.016 15.4 0.1 0.027 14.7 0.1 1.3 1 0 0 1 1 1 0 Gag protein p6 Ank_2 PF12796.7 RLN78513.1 - 3e-204 662.2 49.1 6.7e-23 81.1 0.2 14.6 1 1 14 15 15 15 15 Ankyrin repeats (3 copies) Ank PF00023.30 RLN78513.1 - 1.6e-160 515.3 34.6 3.8e-07 30.3 0.0 27.3 27 0 0 27 27 27 27 Ankyrin repeat Ank_3 PF13606.6 RLN78513.1 - 1.7e-158 494.9 24.7 9.2e-06 25.6 0.0 27.7 28 0 0 28 28 28 27 Ankyrin repeat Ank_4 PF13637.6 RLN78513.1 - 1.2e-148 481.8 77.1 3.7e-10 40.1 0.1 20.8 5 5 21 26 26 26 26 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN78513.1 - 3.4e-133 432.0 58.0 3.5e-08 33.6 0.1 25.3 2 2 24 26 26 26 26 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 RLN78513.1 - 1.3e-39 136.1 0.0 2e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN78513.1 - 3e-37 128.4 0.0 5.5e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain MEDS PF14417.6 RLN78513.1 - 1.1e-08 35.1 11.2 0.89 9.4 0.1 8.0 1 1 11 12 12 12 5 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Nepo_coat_C PF03688.14 RLN78513.1 - 1.4e-06 28.3 25.6 6.8 6.5 0.1 11.1 2 1 14 16 16 16 2 Nepovirus coat protein, C-terminal domain YlzJ PF14035.6 RLN78513.1 - 4.2e-06 26.9 0.0 5e+02 1.0 0.0 10.9 16 0 0 16 16 13 0 YlzJ-like protein VWA_3_C PF18571.1 RLN78513.1 - 1.8e-05 24.5 27.5 32 4.5 0.0 16.1 21 0 0 21 21 21 0 von Willebrand factor type A C-terminal domain Imm_superinfect PF14373.6 RLN78513.1 - 0.43 10.5 31.5 36 4.4 0.0 15.3 22 0 0 22 22 22 0 Superinfection immunity protein SpoIIIAH PF12685.7 RLN78513.1 - 9.6 6.0 7.4 2.2e+02 1.5 0.0 5.8 8 0 0 8 8 8 0 SpoIIIAH-like protein DZR PF12773.7 RLN78514.1 - 5.4e-21 74.4 24.5 1.7e-11 43.9 6.5 2.6 2 0 0 2 2 2 2 Double zinc ribbon zinc_ribbon_2 PF13240.6 RLN78514.1 - 2e-14 52.7 41.6 1.4e-05 24.6 3.4 4.3 4 0 0 4 4 4 4 zinc-ribbon domain zinc_ribbon_15 PF17032.5 RLN78514.1 - 8.7e-14 52.0 18.1 0.002 18.8 0.3 4.4 4 0 0 4 4 4 4 zinc-ribbon family zf-ribbon_3 PF13248.6 RLN78514.1 - 1.6e-08 33.7 37.3 0.00086 18.6 3.5 4.4 4 0 0 4 4 4 3 zinc-ribbon domain UPF0547 PF10571.9 RLN78514.1 - 0.00021 21.3 39.0 0.0078 16.3 7.7 4.4 4 0 0 4 4 4 3 Uncharacterised protein family UPF0547 zinc-ribbon_6 PF10005.9 RLN78514.1 - 0.00027 21.5 22.0 0.85 10.3 0.3 4.4 4 0 0 4 4 4 3 zinc-ribbon domain zf-NADH-PPase PF09297.11 RLN78514.1 - 0.062 13.0 0.2 0.062 13.0 0.2 6.2 6 2 1 7 7 7 0 NADH pyrophosphatase zinc ribbon domain HypA PF01155.19 RLN78514.1 - 0.067 13.2 22.9 0.66 10.0 0.7 4.3 4 0 0 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4_3 PF13920.6 RLN78514.1 - 0.087 12.7 26.4 0.26 11.2 0.4 4.4 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) NOB1_Zn_bind PF08772.11 RLN78514.1 - 0.9 9.7 32.5 0.16 12.1 2.3 4.6 4 0 0 4 4 4 0 Nin one binding (NOB1) Zn-ribbon like zf-AD PF07776.15 RLN78514.1 - 2.1 8.7 12.9 1.3 9.3 0.4 4.0 4 0 0 4 4 4 0 Zinc-finger associated domain (zf-AD) GCK PF07802.11 RLN78515.1 - 7.2e-17 61.6 3.5 1.5e-16 60.5 3.5 1.5 1 0 0 1 1 1 1 GCK domain DUF2000 PF09391.10 RLN78515.1 - 0.033 14.1 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) CX9C PF16860.5 RLN78515.1 - 0.12 12.4 0.1 0.43 10.6 0.1 1.9 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, IQ PF00612.27 RLN78516.1 - 2.4e-23 79.7 190.0 5.9e-05 22.5 1.1 24.9 24 1 1 25 25 25 16 IQ calmodulin-binding motif WW PF00397.26 RLN78516.1 - 2.7e-16 59.4 12.7 1.8e-09 37.5 1.2 2.6 2 0 0 2 2 2 2 WW domain Campylo_MOMP PF05538.11 RLN78516.1 - 0.026 13.5 1.3 5.5 5.9 0.0 2.3 2 0 0 2 2 2 0 Campylobacter major outer membrane protein AAA_8 PF12780.7 RLN78531.1 - 1e-101 339.7 0.4 2.3e-100 335.2 0.1 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 RLN78531.1 - 3.7e-73 244.9 0.5 1.9e-72 242.5 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 RLN78531.1 - 1.8e-27 96.0 0.5 1.7e-26 92.8 0.3 2.9 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RLN78531.1 - 2.2e-19 69.5 0.1 7.8e-19 67.8 0.1 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 RLN78531.1 - 5.7e-16 58.8 0.0 3.7e-13 49.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RLN78531.1 - 1.7e-05 25.1 0.1 0.0042 17.4 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 RLN78531.1 - 0.00012 22.5 0.0 0.0064 16.9 0.0 2.9 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN78531.1 - 0.00071 20.0 0.1 0.027 14.8 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.21 RLN78531.1 - 0.0024 17.3 1.3 0.43 9.9 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 RLN78531.1 - 0.003 17.6 0.1 0.011 15.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.6 RLN78531.1 - 0.0033 17.1 0.3 0.22 11.3 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 RLN78531.1 - 0.0065 17.0 0.0 1.6 9.2 0.0 3.3 3 1 0 3 3 3 1 ABC transporter Sigma54_activat PF00158.26 RLN78531.1 - 0.024 14.4 0.6 0.18 11.5 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain T2SSE PF00437.20 RLN78531.1 - 0.06 12.4 0.1 4 6.4 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 RLN78531.1 - 0.069 13.0 0.0 0.81 9.6 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase NTPase_1 PF03266.15 RLN78531.1 - 0.089 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 NTPase Roc PF08477.13 RLN78531.1 - 0.09 13.0 0.0 0.32 11.2 0.0 2.0 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase IF4E PF01652.18 RLN78531.1 - 0.13 12.1 0.0 0.67 9.7 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic initiation factor 4E AAA_23 PF13476.6 RLN78531.1 - 3.3 8.2 5.0 2.2 8.7 0.1 2.6 2 1 0 2 2 2 0 AAA domain Pkinase_Tyr PF07714.17 RLN78549.1 - 3.7e-63 213.2 0.0 4.9e-63 212.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN78549.1 - 2.5e-54 184.4 0.0 3.4e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain VPS9 PF02204.18 RLN78549.1 - 3.9e-12 46.3 0.0 9.1e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Haspin_kinase PF12330.8 RLN78549.1 - 0.054 12.4 0.0 0.7 8.8 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Trypsin_2 PF13365.6 RLN78550.1 - 6.8e-19 69.2 0.0 1.8e-18 67.9 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain SAM_1 PF00536.30 RLN78550.1 - 3e-09 37.2 0.0 5.4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Trypsin PF00089.26 RLN78550.1 - 3.6e-08 33.5 0.1 2.3e-07 30.8 0.1 1.9 1 1 0 1 1 1 1 Trypsin SAM_2 PF07647.17 RLN78550.1 - 6.3e-06 26.2 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Peptidase_S46 PF10459.9 RLN78550.1 - 0.088 11.4 0.3 4.6 5.7 0.0 2.4 3 0 0 3 3 3 0 Peptidase S46 Terminase_6 PF03237.15 RLN78550.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Terminase-like family HTH_ParB PF17762.1 RLN78550.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 HTH domain found in ParB protein F420_oxidored PF03807.17 RLN78551.1 - 6.4e-13 49.1 0.0 1.3e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 RLN78551.1 - 0.00033 21.1 0.0 0.00047 20.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 RLN78551.1 - 0.0038 17.4 0.1 0.12 12.5 0.0 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 RLN78551.1 - 0.004 17.2 0.0 0.0083 16.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 RLN78551.1 - 0.043 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Med17 PF10156.9 RLN78552.1 - 0.088 11.5 0.0 0.088 11.5 0.0 3.6 4 1 0 5 5 5 0 Subunit 17 of Mediator complex CHORD PF04968.12 RLN78574.1 - 2.9e-43 146.4 24.7 1.2e-21 77.1 6.9 2.3 2 0 0 2 2 2 2 CHORD MafB PF06255.13 RLN78574.1 - 0.068 12.6 0.7 0.13 11.7 0.7 1.4 1 0 0 1 1 1 0 Neisseria toxin MafB BTK PF00779.19 RLN78574.1 - 0.069 13.0 7.0 0.52 10.2 0.2 3.0 3 0 0 3 3 3 0 BTK motif RE_AccI PF09545.10 RLN78574.1 - 0.13 11.2 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 AccI restriction endonuclease NusB PF01029.18 RLN78575.1 - 0.071 13.3 0.2 0.071 13.3 0.2 2.8 2 2 2 4 4 4 0 NusB family TipAS PF07739.13 RLN78575.1 - 0.2 12.2 0.1 0.2 12.2 0.1 2.8 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain P4Ha_N PF08336.11 RLN78575.1 - 0.21 11.6 4.3 1.2 9.2 0.1 2.7 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 7TMR-HDED PF07697.11 RLN78575.1 - 8.9 6.4 12.6 42 4.1 12.6 2.2 1 1 0 1 1 1 0 7TM-HD extracellular zf-HC5HC2H_2 PF13832.6 RLN78576.1 - 1e-19 70.7 16.7 2.2e-15 56.8 1.9 3.3 3 0 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RLN78576.1 - 4.2e-12 46.1 0.8 4.2e-12 46.1 0.8 4.6 4 1 0 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.6 RLN78576.1 - 3.8e-09 36.0 3.2 3.8e-09 36.0 3.2 3.4 4 0 0 4 4 4 1 PHD-finger PHD PF00628.29 RLN78576.1 - 2.3e-05 24.2 7.8 2.3e-05 24.2 7.8 3.4 4 0 0 4 4 4 2 PHD-finger Ada3 PF10198.9 RLN78576.1 - 0.0023 18.0 1.8 0.016 15.4 1.8 2.5 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 Prok-RING_1 PF14446.6 RLN78576.1 - 0.19 11.6 12.1 0.013 15.5 4.3 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FYVE_2 PF02318.16 RLN78576.1 - 1.8 8.8 7.3 0.34 11.1 2.3 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger C1_1 PF00130.22 RLN78576.1 - 4.8 7.1 13.8 0.28 11.1 1.6 3.4 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CCDC-167 PF15188.6 RLN78577.1 - 1.7e-09 37.9 21.1 0.0048 17.2 0.3 5.2 4 2 2 6 6 6 3 Coiled-coil domain-containing protein 167 Fer4_24 PF18109.1 RLN78577.1 - 0.011 16.0 4.3 0.051 13.9 0.1 2.9 3 0 0 3 3 3 0 Ferredoxin I 4Fe-4S cluster domain Baculo_PEP_C PF04513.12 RLN78577.1 - 0.014 15.5 41.9 0.06 13.4 7.7 5.4 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_TATA_bd PF12325.8 RLN78577.1 - 0.03 14.5 42.5 0.66 10.2 3.6 5.1 1 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF2968 PF11180.8 RLN78577.1 - 0.14 11.8 64.0 0.66 9.6 9.8 5.0 1 1 4 5 5 5 0 Protein of unknown function (DUF2968) DUF1664 PF07889.12 RLN78577.1 - 0.18 11.9 29.1 0.98 9.5 0.6 5.6 2 2 5 7 7 7 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 RLN78577.1 - 0.22 11.5 47.3 0.14 12.1 6.0 4.8 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Hemagglutinin PF00509.18 RLN78577.1 - 0.32 9.3 4.0 0.078 11.4 0.5 1.7 2 0 0 2 2 2 0 Haemagglutinin PKcGMP_CC PF16808.5 RLN78577.1 - 0.47 10.4 7.6 11 5.9 0.4 4.5 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase KxDL PF10241.9 RLN78577.1 - 0.77 10.1 33.0 0.8 10.0 1.2 5.4 4 2 1 5 5 5 0 Uncharacterized conserved protein Csm1_N PF18504.1 RLN78577.1 - 1.2 9.5 42.1 1.2 9.6 2.1 8.1 3 3 6 9 9 9 0 Csm1 N-terminal domain APG6_N PF17675.1 RLN78577.1 - 2.5 8.6 55.1 1.4 9.5 10.5 5.6 1 1 4 5 5 5 0 Apg6 coiled-coil region Golgin_A5 PF09787.9 RLN78577.1 - 4.3 6.7 44.8 1.3 8.4 11.3 3.9 1 1 3 4 4 4 0 Golgin subfamily A member 5 DUF5595 PF18077.1 RLN78577.1 - 8.6 6.5 8.2 17 5.6 0.2 4.3 3 2 2 5 5 5 0 Domain of unknown function (DUF5595) SHE3 PF17078.5 RLN78578.1 - 0.00019 21.2 12.8 0.00019 21.2 12.8 9.6 3 1 6 10 10 10 4 SWI5-dependent HO expression protein 3 HMMR_N PF15905.5 RLN78578.1 - 0.0013 18.2 12.1 0.0013 18.2 12.1 9.6 5 1 5 10 10 10 4 Hyaluronan mediated motility receptor N-terminal EzrA PF06160.12 RLN78578.1 - 0.0028 15.9 4.4 0.0028 15.9 4.4 8.1 3 1 5 8 8 8 2 Septation ring formation regulator, EzrA HIP1_clath_bdg PF16515.5 RLN78578.1 - 0.011 16.3 12.2 0.011 16.3 12.2 16.0 4 3 12 16 16 16 0 Clathrin-binding domain of Huntingtin-interacting protein 1 WD40 PF00400.32 RLN78580.1 - 3.5e-09 37.1 11.2 0.24 12.3 0.0 6.4 5 1 0 5 5 5 3 WD domain, G-beta repeat PALB2_WD40 PF16756.5 RLN78580.1 - 0.00019 20.5 0.6 0.0017 17.4 0.2 2.4 2 0 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain Tap-RNA_bind PF09162.10 RLN78580.1 - 0.049 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Tap, RNA-binding ANAPC4_WD40 PF12894.7 RLN78580.1 - 0.08 13.2 0.3 1.9 8.9 0.1 3.1 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Aa_trans PF01490.18 RLN78581.1 - 1.2e-41 142.7 15.8 1.8e-41 142.2 15.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 RLN78582.1 - 1.2e-41 142.8 14.0 2.7e-41 141.6 14.0 1.5 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein LRR_9 PF14580.6 RLN78585.1 - 1.7e-18 66.7 12.6 2.4e-13 50.0 0.7 2.2 1 1 2 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 RLN78585.1 - 2.1e-13 50.2 31.9 7.6e-06 26.2 1.7 5.2 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN78585.1 - 7.3e-13 48.1 31.9 5.1e-07 29.4 6.5 4.3 1 1 4 5 5 5 5 Leucine rich repeat FTH PF01827.27 RLN78585.1 - 0.057 13.2 1.6 0.12 12.2 1.4 1.7 1 1 0 1 1 1 0 FTH domain PfkB PF00294.24 RLN78585.1 - 0.068 12.5 0.8 0.35 10.1 0.1 1.9 1 1 1 2 2 2 0 pfkB family carbohydrate kinase LRR_1 PF00560.33 RLN78585.1 - 0.095 13.3 21.3 1.9 9.4 0.2 6.2 4 3 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 RLN78585.1 - 0.41 10.8 19.8 1.5 9.1 0.2 5.8 5 1 1 6 6 6 0 Leucine Rich repeat cNMP_binding PF00027.29 RLN78586.1 - 1e-58 195.4 1.7 4e-20 71.7 0.0 4.4 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Pkinase PF00069.25 RLN78586.1 - 1.6e-56 191.6 0.0 2.4e-56 191.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN78586.1 - 1.1e-27 96.9 0.0 1.8e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN78586.1 - 0.0012 18.3 0.0 0.003 16.9 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 RLN78586.1 - 0.0024 17.0 0.0 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 ABC1 PF03109.16 RLN78586.1 - 0.004 17.3 0.0 2.7 8.2 0.0 2.4 2 0 0 2 2 2 2 ABC1 family APH PF01636.23 RLN78586.1 - 0.056 13.4 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Hexapep PF00132.24 RLN78587.1 - 3.8e-07 29.6 7.1 0.00027 20.6 0.4 3.7 3 1 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 RLN78587.1 - 8.9e-05 22.2 0.1 0.28 11.0 0.1 3.2 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase ADH_N PF08240.12 RLN78588.1 - 4.3e-25 87.7 3.3 4.3e-25 87.7 3.3 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN78588.1 - 1.8e-16 60.3 0.0 2.8e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN78588.1 - 0.00052 21.1 0.0 0.00079 20.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN78588.1 - 0.0012 18.3 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN78588.1 - 0.02 14.2 0.1 0.035 13.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aa_trans PF01490.18 RLN78589.1 - 1.6e-43 149.0 14.5 2.3e-43 148.5 14.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein LRR_8 PF13855.6 RLN78590.1 - 0.21 11.4 16.9 1.5 8.6 0.2 5.8 4 3 2 6 6 6 0 Leucine rich repeat LRR_8 PF13855.6 RLN78591.1 - 0.0087 15.8 0.0 0.061 13.1 0.0 2.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_8 PF13855.6 RLN78592.1 - 0.045 13.5 0.8 0.85 9.4 0.1 3.1 2 1 1 3 3 3 0 Leucine rich repeat Sugar_tr PF00083.24 RLN78606.1 - 1.2e-52 179.3 26.4 1.7e-52 178.8 26.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN78606.1 - 8.1e-30 103.9 50.8 2.7e-25 89.0 29.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 RLN78606.1 - 2.2e-06 27.2 7.6 2.2e-06 27.2 7.6 2.1 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB PARP PF00644.20 RLN78607.1 - 0.043 13.4 0.1 0.12 12.0 0.1 1.8 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain UPF0086 PF01868.16 RLN78609.1 - 5e-06 26.4 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function UPF0086 PigN PF04987.14 RLN78610.1 - 6.2e-108 361.6 24.0 8.1e-108 361.2 24.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 RLN78610.1 - 2.1e-07 30.9 1.1 3.2e-05 23.7 0.6 2.4 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RLN78610.1 - 0.0062 16.0 0.2 0.0099 15.3 0.2 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 RLN78610.1 - 0.018 14.4 0.1 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Host_attach PF10116.9 RLN78610.1 - 0.13 12.9 0.0 0.4 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein required for attachment to host cells Tetraspanin PF00335.20 RLN78610.1 - 0.15 11.7 0.0 0.15 11.7 0.0 2.8 2 1 0 3 3 3 0 Tetraspanin family ELMO_CED12 PF04727.13 RLN78611.1 - 1.1e-24 87.5 0.0 4.7e-24 85.4 0.0 1.9 2 0 0 2 2 2 1 ELMO/CED-12 family PH PF00169.29 RLN78611.1 - 1.5e-17 64.0 0.0 4.2e-13 49.7 0.0 2.9 3 0 0 3 3 3 2 PH domain DUF5528 PF17666.1 RLN78611.1 - 0.16 12.0 0.0 0.43 10.5 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5528) TPR_12 PF13424.6 RLN78612.1 - 2.2e-19 69.5 6.0 0.0027 18.0 0.0 5.7 4 1 1 5 5 5 5 Tetratricopeptide repeat SAM_1 PF00536.30 RLN78612.1 - 3.2e-18 65.9 0.0 6.9e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RLN78612.1 - 3.9e-14 52.5 0.0 1e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TPR_10 PF13374.6 RLN78612.1 - 5.3e-12 45.2 21.6 0.028 14.3 0.0 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat CHAT PF12770.7 RLN78612.1 - 8.8e-10 38.5 2.2 2.7e-09 36.9 2.2 1.8 1 0 0 1 1 1 1 CHAT domain NACHT PF05729.12 RLN78612.1 - 2.1e-06 27.7 0.0 5.5e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain TPR_17 PF13431.6 RLN78612.1 - 4.4e-05 23.6 0.2 0.45 11.0 0.0 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat AAA_25 PF13481.6 RLN78612.1 - 6.9e-05 22.5 0.0 0.00019 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RLN78612.1 - 0.0059 17.0 0.0 0.025 15.0 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RLN78612.1 - 0.0065 16.7 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 RLN78612.1 - 0.02 15.3 0.0 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SAM_4 PF18017.1 RLN78612.1 - 0.063 13.3 0.0 0.74 9.8 0.0 2.2 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) RhlB PF12300.8 RLN78612.1 - 1.2 9.2 13.3 0.81 9.8 10.3 2.3 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB MitMem_reg PF13012.6 RLN78613.1 - 5e-21 75.2 0.0 3.2e-20 72.6 0.0 2.0 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 RLN78613.1 - 6.2e-11 42.3 0.0 1.9e-10 40.8 0.0 1.7 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Peptidase_M50B PF13398.6 RLN78615.1 - 3.9e-32 111.5 17.9 1.8e-28 99.5 16.5 2.1 2 0 0 2 2 2 2 Peptidase M50B-like DUF1286 PF06939.11 RLN78615.1 - 0.013 15.7 1.0 0.013 15.7 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1286) Herpes_LMP1 PF05297.11 RLN78615.1 - 4.4 6.4 10.9 5.2 6.1 10.9 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) YihI PF04220.12 RLN78629.1 - 1.1 8.9 9.7 2.7 7.7 9.7 1.7 1 0 0 1 1 1 0 Der GTPase activator (YihI) Pkinase PF00069.25 RLN78630.1 - 2.1e-72 243.7 0.1 3e-72 243.2 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN78630.1 - 3.9e-37 127.9 0.0 5.6e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 RLN78630.1 - 3e-16 59.6 1.0 1.4e-06 28.6 0.0 4.4 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.32 RLN78630.1 - 1.4e-15 55.6 1.2 5.5e-06 25.6 0.3 4.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RLN78630.1 - 5.7e-14 51.7 1.4 2.4e-06 27.3 0.1 4.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 RLN78630.1 - 3.4e-12 45.2 2.5 0.058 13.4 0.0 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 RLN78630.1 - 4.3e-08 32.3 0.1 0.005 16.3 0.1 3.8 3 0 0 3 3 3 2 EF hand Kdo PF06293.14 RLN78630.1 - 0.0013 18.1 0.2 0.0024 17.2 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN78630.1 - 0.0016 18.4 0.2 0.5 10.2 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family EF-hand_4 PF12763.7 RLN78630.1 - 0.017 15.1 0.1 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 RLN78630.1 - 0.16 12.3 0.5 0.57 10.6 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain Metallophos PF00149.28 RLN78632.1 - 5.8e-12 46.5 0.2 1e-11 45.7 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LBR_tudor PF09465.10 RLN78653.1 - 0.013 15.3 0.2 0.04 13.7 0.2 1.8 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain TUDOR_5 PF18359.1 RLN78653.1 - 0.15 11.8 0.3 0.45 10.2 0.0 1.9 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain 1 Peptidase_M14 PF00246.24 RLN78654.1 - 3.9e-13 49.9 0.0 8.3e-13 48.8 0.0 1.5 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 RLN78654.1 - 4.1e-05 23.9 1.1 0.0001 22.6 0.8 1.8 2 0 0 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain DUF389 PF04087.14 RLN78655.1 - 3.8e-23 82.1 9.4 5e-23 81.7 9.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF389) Gly-zipper_Omp PF13488.6 RLN78655.1 - 8.3 6.5 8.5 14 5.8 7.0 2.1 2 0 0 2 2 2 0 Glycine zipper DIM1 PF02966.16 RLN78656.1 - 3.5e-23 81.9 0.1 1.3e-11 44.4 0.1 2.0 2 0 0 2 2 2 2 Mitosis protein DIM1 Thioredoxin PF00085.20 RLN78656.1 - 0.023 14.7 0.0 0.05 13.6 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin TPR_2 PF07719.17 RLN78657.1 - 3.7e-23 79.7 32.4 3.2e-05 23.7 2.0 11.4 11 1 1 12 12 12 6 Tetratricopeptide repeat TPR_1 PF00515.28 RLN78657.1 - 1.1e-21 75.7 19.6 0.00081 19.1 1.6 10.0 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 RLN78657.1 - 2.2e-18 64.9 10.5 0.0019 18.3 0.3 9.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 RLN78657.1 - 9.9e-15 54.0 20.6 0.00057 19.5 0.0 8.1 8 1 0 8 8 8 3 TPR repeat TPR_14 PF13428.6 RLN78657.1 - 7e-12 45.1 28.2 0.32 11.9 0.1 8.6 7 3 2 9 9 8 5 Tetratricopeptide repeat TPR_9 PF13371.6 RLN78657.1 - 2.3e-09 37.3 23.1 0.01 15.9 0.3 6.4 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 RLN78657.1 - 1.8e-08 34.8 12.8 0.015 15.8 0.3 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 RLN78657.1 - 5.1e-06 25.9 12.8 0.062 12.5 0.2 5.4 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 RLN78657.1 - 2.1e-05 25.1 27.4 0.11 13.2 0.1 6.9 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN78657.1 - 4.8e-05 23.4 1.7 0.81 10.2 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN78657.1 - 6.7e-05 23.1 25.9 0.04 14.2 1.3 7.5 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN78657.1 - 8.3e-05 22.3 11.9 0.43 10.7 0.1 6.9 5 2 1 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN78657.1 - 0.049 13.9 10.0 0.4 10.9 0.5 4.6 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.6 RLN78657.1 - 0.58 10.6 4.8 2.6 8.5 0.2 3.6 4 0 0 4 4 4 0 Alkyl sulfatase dimerisation DUF3856 PF12968.7 RLN78657.1 - 1.9 8.6 7.1 27 4.8 0.8 4.3 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) Dynein_light PF01221.18 RLN78658.1 - 6e-28 97.0 1.6 6.6e-28 96.9 1.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 BBE PF08031.12 RLN78659.1 - 1.5e-17 63.4 0.1 2.5e-17 62.7 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 RLN78659.1 - 0.00011 22.0 2.7 0.00011 22.0 2.7 2.1 3 0 0 3 3 3 1 FAD binding domain FAD_binding_4 PF01565.23 RLN78660.1 - 8.5e-06 25.6 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain TrbC PF04956.13 RLN78660.1 - 0.25 11.6 1.1 0.41 10.9 1.1 1.3 1 0 0 1 1 1 0 TrbC/VIRB2 family Arf PF00025.21 RLN78682.1 - 2e-54 183.7 0.0 4e-53 179.4 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RLN78682.1 - 6.2e-09 36.1 0.0 8.6e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 RLN78682.1 - 1.4e-08 34.4 0.0 7.6e-05 22.0 0.0 2.3 1 1 0 2 2 2 2 G-protein alpha subunit Ras PF00071.22 RLN78682.1 - 2e-06 27.5 0.0 3.1e-06 26.9 0.0 1.3 1 1 0 1 1 1 1 Ras family SRPRB PF09439.10 RLN78682.1 - 3.3e-05 23.4 0.0 5.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 RLN78682.1 - 6.8e-05 22.5 0.0 8.2e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RLN78682.1 - 0.00011 22.3 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RLN78682.1 - 0.00085 18.7 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 RLN78682.1 - 0.069 13.4 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 RLN78682.1 - 0.1 12.2 0.0 2.4 7.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Antibiotic_NAT PF02522.14 RLN78682.1 - 0.21 11.3 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase PduV-EutP PF10662.9 RLN78682.1 - 0.22 11.3 0.0 0.39 10.5 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation EAP30 PF04157.16 RLN78683.1 - 7.4e-53 179.3 0.1 5.2e-42 143.8 0.0 2.0 1 1 1 2 2 2 2 EAP30/Vps36 family ASH PF15780.5 RLN78684.1 - 2.2e-05 24.6 0.0 0.4 10.9 0.0 2.7 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 RLN78684.1 - 0.00045 20.3 0.5 0.0028 17.8 0.1 2.3 2 0 0 2 2 2 1 Flagellar-associated PapD-like Myc_N PF01056.18 RLN78684.1 - 0.017 15.0 1.4 0.017 15.0 1.4 1.8 2 0 0 2 2 2 0 Myc amino-terminal region DUF1180 PF06679.12 RLN78684.1 - 0.35 11.3 3.4 2.9 8.3 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) TFIIE-A_C PF11521.8 RLN78684.1 - 6.3 7.2 7.8 1.7 9.0 0.8 2.8 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Sulfotransfer_3 PF13469.6 RLN78713.1 - 3.5e-10 40.6 0.1 1.5e-09 38.6 0.0 2.1 2 0 0 2 2 2 1 Sulfotransferase family Asp_Arg_Hydrox PF05118.15 RLN78713.1 - 3e-08 33.7 0.1 6.1e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Sulfotransfer_1 PF00685.27 RLN78713.1 - 1.5e-07 31.2 0.0 9.1e-07 28.6 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Thi4 PF01946.17 RLN78714.1 - 3.1e-104 347.3 1.3 4.4e-104 346.8 1.3 1.1 1 0 0 1 1 1 1 Thi4 family DUF1126 PF06565.12 RLN78714.1 - 9.6e-72 237.5 2.9 6.6e-26 90.2 0.1 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain FAD_binding_2 PF00890.24 RLN78714.1 - 6e-08 32.2 1.7 1.7e-05 24.1 0.7 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 RLN78714.1 - 2.4e-06 27.4 3.3 2e-05 24.3 1.1 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 RLN78714.1 - 7.8e-06 25.5 0.1 1.2e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RLN78714.1 - 9.7e-06 25.7 0.1 2.1e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 RLN78714.1 - 0.0003 20.1 0.1 0.00044 19.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 RLN78714.1 - 0.0026 16.9 2.5 0.17 11.0 0.8 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A GMC_oxred_N PF00732.19 RLN78714.1 - 0.0027 17.1 0.2 0.15 11.4 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_3 PF01494.19 RLN78714.1 - 0.0065 15.8 0.1 0.046 13.0 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 RLN78714.1 - 0.0082 14.9 1.8 0.0085 14.8 0.6 1.5 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 RLN78714.1 - 0.017 14.2 0.4 0.035 13.2 0.4 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 RLN78714.1 - 0.087 12.8 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 RLN78714.1 - 0.11 11.4 0.5 0.15 10.9 0.5 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Ribosomal_L23eN PF03939.13 RLN78740.1 - 7.7e-17 61.2 5.9 1.7e-16 60.1 5.9 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 RLN78740.1 - 2.1e-16 60.1 1.3 2.1e-16 60.1 1.3 2.3 2 2 0 2 2 2 1 Ribosomal protein L23 YihI PF04220.12 RLN78740.1 - 0.017 14.8 0.2 0.021 14.5 0.2 1.3 1 1 0 1 1 1 0 Der GTPase activator (YihI) Striatin PF08232.12 RLN78741.1 - 6.1e-17 62.6 3.5 9.1e-17 62.1 3.5 1.3 1 0 0 1 1 1 1 Striatin family WD40 PF00400.32 RLN78741.1 - 7.8e-14 51.9 0.3 6.3e-06 26.8 0.0 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 RLN78741.1 - 0.0022 16.8 0.0 1.1 7.9 0.0 2.2 2 0 0 2 2 2 2 Nup133 N terminal like DUF3450 PF11932.8 RLN78741.1 - 0.0047 16.3 3.0 0.0071 15.7 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) ANAPC4_WD40 PF12894.7 RLN78741.1 - 0.05 13.9 0.0 4.6 7.6 0.0 3.3 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain VPS13 PF16908.5 RLN78742.1 - 1e-44 153.1 6.4 6.6e-44 150.5 2.7 3.4 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 RLN78742.1 - 3e-43 147.9 0.0 6.8e-37 127.1 0.0 5.0 4 1 0 4 4 4 3 Repeating coiled region of VPS13 Chorein_N PF12624.7 RLN78742.1 - 3.4e-23 82.0 0.0 1.5e-22 79.9 0.0 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 p450 PF00067.22 RLN78743.1 - 3.7e-11 42.5 0.0 4.1e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CoatB PF10389.9 RLN78743.1 - 0.37 10.7 1.8 0.72 9.7 0.2 2.0 2 0 0 2 2 2 0 Bacteriophage coat protein B RecQ_Zn_bind PF16124.5 RLN78744.1 - 6.3e-16 58.9 2.5 6.3e-16 58.9 2.5 2.0 2 0 0 2 2 2 1 RecQ zinc-binding Helicase_C PF00271.31 RLN78744.1 - 2.4e-13 50.4 0.0 4.3e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RLN78744.1 - 0.00022 21.0 0.0 0.00047 20.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase TFIIS_C PF01096.18 RLN78745.1 - 4.4e-19 68.0 5.7 4.4e-19 68.0 5.7 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 RLN78745.1 - 6.8e-06 26.0 1.6 6.8e-06 26.0 1.6 1.8 2 0 0 2 2 2 1 Transposase zinc-ribbon domain zf-RRPl_C4 PF17026.5 RLN78745.1 - 0.018 15.1 2.4 0.024 14.7 2.4 1.2 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Terminase_GpA PF05876.12 RLN78745.1 - 0.019 13.5 2.5 0.024 13.2 2.5 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zf-Dof PF02701.15 RLN78745.1 - 0.03 14.5 7.6 0.19 11.9 4.9 2.2 2 0 0 2 2 2 0 Dof domain, zinc finger zinc_ribbon_4 PF13717.6 RLN78745.1 - 0.15 12.0 8.1 6.4 6.8 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain HypA PF01155.19 RLN78745.1 - 0.66 10.0 4.6 0.44 10.6 0.4 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Tnp_zf-ribbon_2 PF13842.6 RLN78745.1 - 1.5 9.7 10.8 14 6.6 0.1 2.8 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Pkinase PF00069.25 RLN78746.1 - 2.1e-44 151.9 0.0 2.9e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN78746.1 - 1e-28 100.4 0.0 1.5e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase ELP6 PF09807.9 RLN78746.1 - 2.4e-23 82.8 0.3 1.4e-20 73.7 0.3 2.2 1 1 0 1 1 1 1 Elongation complex protein 6 Kdo PF06293.14 RLN78746.1 - 7.7e-05 22.1 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN78746.1 - 0.00078 18.8 0.1 0.0018 17.6 0.1 1.7 1 1 0 1 1 1 1 Kinase-like Elong_Iki1 PF10483.9 RLN78746.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 ATPase PF06745.13 RLN78746.1 - 0.024 14.0 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 KaiC MEDS PF14417.6 RLN78746.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain SpoU_methylase PF00588.19 RLN78747.1 - 1.9e-25 89.7 0.4 4.4e-25 88.5 0.0 1.9 2 0 0 2 2 2 1 SpoU rRNA Methylase family ORC5_C PF14630.6 RLN78747.1 - 0.28 10.7 1.3 3.1 7.2 0.1 2.8 3 0 0 3 3 3 0 Origin recognition complex (ORC) subunit 5 C-terminus zf-RanBP PF00641.18 RLN78768.1 - 5.3e-05 22.4 0.8 9.6e-05 21.6 0.8 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DZR PF12773.7 RLN78768.1 - 0.041 13.9 0.6 0.07 13.2 0.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon UCH PF00443.29 RLN78769.1 - 6.3e-15 55.4 0.0 8.7e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN78769.1 - 1.7e-10 41.0 0.0 5.5e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PDZ PF00595.24 RLN78769.1 - 0.00012 22.4 0.0 0.00024 21.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RLN78769.1 - 0.00053 19.8 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain zf-RanBP PF00641.18 RLN78769.1 - 0.0072 15.6 1.7 0.0072 15.6 1.7 2.3 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others PDZ_2 PF13180.6 RLN78769.1 - 0.095 13.0 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 PDZ domain TRP PF06011.12 RLN78770.1 - 0.068 11.9 7.3 0.081 11.6 7.3 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel EloA-BP1 PF15870.5 RLN78771.1 - 0.0025 18.1 1.8 0.013 15.8 1.4 1.9 1 1 1 2 2 2 1 ElonginA binding-protein 1 Phage_integrase PF00589.22 RLN78794.1 - 0.00037 20.3 0.0 0.0006 19.6 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Pkinase_Tyr PF07714.17 RLN78796.1 - 0.0053 16.1 0.0 0.0085 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SK_channel PF03530.14 RLN78812.1 - 1.2e-21 76.8 1.1 3.9e-21 75.2 1.1 1.9 1 0 0 1 1 1 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 RLN78812.1 - 6.9e-13 48.4 4.5 1.7e-12 47.1 4.5 1.6 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 RLN78812.1 - 0.011 15.0 1.2 0.02 14.1 1.3 1.5 1 1 0 1 1 1 0 Ion transport protein C2 PF00168.30 RLN78813.1 - 6.2e-07 29.7 0.0 2.1e-06 28.0 0.0 2.0 2 1 0 2 2 2 1 C2 domain Peptidase_M16_M PF16187.5 RLN78814.1 - 9.3e-60 202.3 0.0 1.3e-59 201.8 0.0 1.2 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 RLN78814.1 - 1.1e-31 109.8 0.0 2.6e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 RLN78814.1 - 1.8e-23 83.5 0.0 2.8e-14 53.6 0.0 2.3 2 0 0 2 2 2 2 Peptidase M16 inactive domain L27_2 PF09045.10 RLN78814.1 - 0.15 12.1 1.0 17 5.4 0.0 2.9 2 0 0 2 2 2 0 L27_2 NGP1NT PF08153.12 RLN78815.1 - 1.5e-45 154.5 0.0 2.1e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 NGP1NT (NUC091) domain RRM_1 PF00076.22 RLN78816.1 - 1.1e-15 57.2 0.0 1.9e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RLN78816.1 - 1.7e-07 30.8 0.0 2.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.7 RLN78817.1 - 5.9e-19 68.4 7.8 2.2e-08 34.6 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN78817.1 - 8.3e-16 57.8 12.1 0.024 14.9 0.0 8.1 5 1 4 9 9 9 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN78817.1 - 9e-15 54.8 13.0 2.6e-06 27.9 0.2 6.7 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN78817.1 - 3.7e-12 45.3 6.5 1.8 9.4 0.0 8.7 9 0 0 9 9 9 3 Ankyrin repeat Ank PF00023.30 RLN78817.1 - 4.2e-05 23.8 0.6 22 5.7 0.0 5.6 2 1 2 4 4 4 0 Ankyrin repeat DUF5049 PF16468.5 RLN78817.1 - 0.003 17.4 0.7 13 5.8 0.0 4.5 2 1 3 5 5 5 1 Domain of unknown function (DUF5049) VHL_C PF17211.3 RLN78817.1 - 0.008 16.2 0.2 17 5.5 0.0 4.3 4 0 0 4 4 4 1 VHL box domain DUF249 PF03158.13 RLN78817.1 - 0.056 13.1 0.1 1.7 8.3 0.0 2.9 2 1 1 3 3 3 0 Multigene family 530 protein DUF4175 PF13779.6 RLN78817.1 - 1.3 6.9 3.5 1.7 6.4 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CopD PF05425.13 RLN78817.1 - 1.4 9.3 8.1 0.7 10.3 5.3 1.9 2 0 0 2 2 2 0 Copper resistance protein D RCC1 PF00415.18 RLN78840.1 - 9e-22 77.4 0.0 7.9e-10 39.2 0.0 2.1 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN78840.1 - 3.7e-10 39.3 1.1 1.9e-05 24.3 0.0 3.2 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat Elicitin PF00964.17 RLN78841.1 - 2.7e-15 56.2 7.4 3.7e-15 55.8 7.4 1.2 1 0 0 1 1 1 1 Elicitin PAP_assoc PF03828.19 RLN78842.1 - 2.6e-05 24.3 0.3 0.00022 21.3 0.1 2.5 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 RLN78842.1 - 0.00012 22.3 0.0 0.00032 20.9 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain NPV_P10 PF05531.12 RLN78842.1 - 3.7 8.1 5.6 3.7 8.1 2.6 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DASH_Dam1 PF08653.10 RLN78843.1 - 1.4e-09 37.6 0.0 2.1e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 DUF3136 PF11334.8 RLN78843.1 - 0.11 12.4 0.0 11 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) HOOK PF05622.12 RLN78844.1 - 0.0016 16.7 15.1 0.002 16.4 15.1 1.2 1 0 0 1 1 1 1 HOOK protein YabA PF06156.13 RLN78844.1 - 0.0049 17.5 15.0 0.023 15.3 1.1 2.6 1 1 1 2 2 2 1 Initiation control protein YabA LUC7 PF03194.15 RLN78844.1 - 0.014 15.1 10.8 0.018 14.7 10.8 1.2 1 0 0 1 1 1 0 LUC7 N_terminus ADIP PF11559.8 RLN78844.1 - 0.019 15.1 28.5 0.1 12.7 11.3 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF16 PF01519.16 RLN78844.1 - 0.02 15.3 7.8 0.02 15.3 7.8 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF3584 PF12128.8 RLN78844.1 - 0.033 11.7 17.2 0.04 11.5 17.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6_N PF17675.1 RLN78844.1 - 0.087 13.4 34.5 0.11 13.0 23.7 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4686 PF15742.5 RLN78844.1 - 0.1 11.7 25.3 0.13 11.4 25.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) FPP PF05911.11 RLN78844.1 - 0.12 10.5 17.9 0.17 10.0 17.9 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Nup88 PF10168.9 RLN78844.1 - 0.13 10.0 9.3 0.17 9.7 9.3 1.2 1 0 0 1 1 1 0 Nuclear pore component V_ATPase_I PF01496.19 RLN78844.1 - 0.18 9.7 10.2 0.24 9.3 10.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MtrB PF05440.12 RLN78844.1 - 0.19 12.2 0.1 0.56 10.7 0.0 1.8 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF812 PF05667.11 RLN78844.1 - 0.26 10.1 18.2 0.42 9.4 18.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) GAS PF13851.6 RLN78844.1 - 0.26 10.6 26.9 0.3 10.4 15.2 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 RLN78844.1 - 0.28 11.2 22.6 0.57 10.2 22.0 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Exonuc_VII_L PF02601.15 RLN78844.1 - 0.3 10.6 12.1 0.42 10.1 12.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prominin PF05478.11 RLN78844.1 - 0.37 8.7 13.5 0.5 8.2 13.5 1.1 1 0 0 1 1 1 0 Prominin Filament PF00038.21 RLN78844.1 - 0.43 10.1 25.2 0.16 11.5 12.5 2.1 1 1 1 2 2 2 0 Intermediate filament protein TMF_DNA_bd PF12329.8 RLN78844.1 - 0.44 10.6 19.9 0.064 13.3 4.7 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 RLN78844.1 - 0.63 10.1 11.4 0.33 11.0 7.6 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Fmp27_WPPW PF10359.9 RLN78844.1 - 1.3 7.7 16.7 0.05 12.5 5.5 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Syntaxin-6_N PF09177.11 RLN78844.1 - 1.5 9.4 19.5 5.2 7.7 5.5 3.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal ERM PF00769.19 RLN78844.1 - 1.8 8.3 33.1 0.77 9.5 26.7 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family bZIP_2 PF07716.15 RLN78844.1 - 1.8 8.7 28.7 0.7 10.0 6.2 3.6 3 0 0 3 3 3 0 Basic region leucine zipper KASH_CCD PF14662.6 RLN78844.1 - 2.1 8.1 29.8 1.3 8.8 12.1 2.5 2 1 1 3 3 2 0 Coiled-coil region of CCDC155 or KASH DUF4337 PF14235.6 RLN78844.1 - 2.3 8.3 19.1 2.8 8.0 5.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) UPF0242 PF06785.11 RLN78844.1 - 2.7 8.1 28.8 1.5 8.8 15.3 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ax_dynein_light PF10211.9 RLN78844.1 - 2.7 7.9 23.5 12 5.8 15.3 2.5 1 1 1 2 2 2 0 Axonemal dynein light chain FlaC_arch PF05377.11 RLN78844.1 - 3.3 8.2 8.4 23 5.5 0.3 3.3 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Atg14 PF10186.9 RLN78844.1 - 3.3 6.7 17.7 13 4.8 17.6 1.9 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Synaptobrevin PF00957.21 RLN78844.1 - 3.5 7.5 6.7 8 6.3 1.3 2.8 2 1 0 2 2 2 0 Synaptobrevin Cnn_1N PF07989.11 RLN78844.1 - 3.9 7.7 19.9 1.1 9.5 5.1 3.5 2 1 2 4 4 3 0 Centrosomin N-terminal motif 1 XhlA PF10779.9 RLN78844.1 - 4.2 7.6 15.8 2.6 8.3 1.4 2.9 3 1 0 3 3 3 0 Haemolysin XhlA bZIP_1 PF00170.21 RLN78844.1 - 4.3 7.5 19.9 0.73 10.0 0.7 4.0 3 1 2 5 5 5 0 bZIP transcription factor zf-CpG_bind_C PF12269.8 RLN78844.1 - 4.7 6.9 12.9 0.5 10.1 6.1 2.2 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain Fib_alpha PF08702.10 RLN78844.1 - 4.9 7.3 14.5 2 8.6 9.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Mt_ATP-synt_D PF05873.12 RLN78844.1 - 5.9 6.7 8.5 17 5.2 0.7 2.3 1 1 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Fzo_mitofusin PF04799.13 RLN78844.1 - 6.5 6.3 16.1 0.76 9.3 2.5 2.6 1 1 1 2 2 2 0 fzo-like conserved region LMBR1 PF04791.16 RLN78844.1 - 8.3 5.2 6.9 9.1 5.1 6.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4763 PF15960.5 RLN78844.1 - 8.4 5.6 23.5 38 3.5 23.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) AAA_13 PF13166.6 RLN78844.1 - 8.6 4.9 18.1 1.3 7.6 8.3 1.9 1 1 1 2 2 2 0 AAA domain Mito_carr PF00153.27 RLN78845.1 - 9e-51 169.8 6.4 8.6e-20 70.5 0.1 3.9 3 1 1 4 4 4 4 Mitochondrial carrier protein ASFV_L11L PF05293.11 RLN78845.1 - 0.068 13.5 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 African swine fever virus (ASFV) L11L protein GTP_EFTU PF00009.27 RLN78846.1 - 3.7e-31 108.2 0.4 1.1e-30 106.7 0.4 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 RLN78846.1 - 9.4e-15 54.6 1.2 2e-14 53.6 0.4 2.0 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 RLN78846.1 - 7.7e-08 32.4 0.0 1.8e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RLN78846.1 - 9.3e-07 28.9 0.0 0.00043 20.2 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 RLN78846.1 - 0.00011 21.8 0.0 0.00062 19.3 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 RLN78846.1 - 0.00086 18.4 0.1 0.0024 16.9 0.1 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 RLN78846.1 - 0.0012 18.7 0.0 0.0031 17.3 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 RLN78846.1 - 0.0077 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Ras family AAA_25 PF13481.6 RLN78846.1 - 0.024 14.2 0.1 0.071 12.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 RLN78846.1 - 0.093 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Septin Aa_trans PF01490.18 RLN78847.1 - 5.8e-67 226.2 26.0 7.2e-67 225.9 26.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 RLN78847.1 - 1.6e-09 37.3 16.8 1.6e-09 37.3 16.8 1.8 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family Spore_permease PF03845.13 RLN78847.1 - 0.0025 16.7 18.0 0.0025 16.7 18.0 2.2 2 1 0 2 2 2 1 Spore germination protein LMBR1 PF04791.16 RLN78848.1 - 1.2e-07 31.0 4.5 1.3e-07 30.9 4.5 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Viral_Beta_CD PF04530.12 RLN78848.1 - 0.19 12.1 2.0 0.18 12.1 2.0 1.1 1 0 0 1 1 1 0 Viral Beta C/D like family DHHC PF01529.20 RLN78848.1 - 0.22 11.7 1.8 0.28 11.3 1.8 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Tetraspanin PF00335.20 RLN78848.1 - 0.47 10.1 2.4 0.52 10.0 2.4 1.0 1 0 0 1 1 1 0 Tetraspanin family FH2 PF02181.23 RLN78850.1 - 1.3e-43 149.6 0.1 1.6e-43 149.2 0.1 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain Cucumopine_C PF18631.1 RLN78850.1 - 0.023 14.6 0.1 0.097 12.6 0.0 2.0 2 0 0 2 2 2 0 Cucumopine synthase C-terminal helical bundle domain ALIX_LYPXL_bnd PF13949.6 RLN78850.1 - 0.029 13.7 0.7 0.043 13.1 0.7 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV MscS_porin PF12795.7 RLN78850.1 - 0.063 12.8 0.5 0.1 12.1 0.5 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain SelP_N PF04592.14 RLN78850.1 - 1.8 7.9 13.2 2.8 7.3 13.2 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MIOX PF05153.15 RLN78867.1 - 2e-40 139.0 3.3 2.2e-40 138.8 3.3 1.0 1 0 0 1 1 1 1 Myo-inositol oxygenase Sdh5 PF03937.16 RLN78867.1 - 0.087 12.8 0.4 0.15 12.0 0.4 1.5 1 1 0 1 1 1 0 Flavinator of succinate dehydrogenase LSM PF01423.22 RLN78868.1 - 4.4e-14 51.9 0.0 8.2e-14 51.0 0.0 1.5 1 1 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RLN78868.1 - 0.0016 18.5 0.0 0.0025 17.9 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2642 PF10842.8 RLN78868.1 - 0.11 12.3 0.1 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) RasGEF PF00617.19 RLN78888.1 - 5.5e-25 88.6 0.0 9.1e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain PH PF00169.29 RLN78888.1 - 0.026 15.1 0.0 0.06 13.9 0.0 1.6 1 0 0 1 1 1 0 PH domain CENP-C_C PF11699.8 RLN78889.1 - 4.2e-07 30.1 0.0 0.00027 21.1 0.1 2.5 2 0 0 2 2 2 2 Mif2/CENP-C like Cupin_1 PF00190.22 RLN78889.1 - 0.071 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.11 RLN78889.1 - 0.18 11.6 0.0 0.68 9.7 0.0 1.9 2 0 0 2 2 2 0 Cupin domain LRR_8 PF13855.6 RLN78890.1 - 1.6e-09 37.4 2.5 1.7e-07 30.9 0.2 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RLN78890.1 - 8.9e-09 35.5 2.1 1.5e-05 25.2 0.5 2.3 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) Mid2 PF04478.12 RLN78890.1 - 0.00073 19.4 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 RLN78890.1 - 0.008 15.9 0.2 0.016 15.0 0.2 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Tweety PF04906.13 RLN78890.1 - 0.0092 14.7 0.1 0.014 14.1 0.1 1.2 1 0 0 1 1 1 1 Tweety Pkinase_Tyr PF07714.17 RLN78890.1 - 0.02 14.2 0.1 0.029 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase TMEM154 PF15102.6 RLN78890.1 - 0.022 14.7 0.1 0.047 13.6 0.1 1.6 1 1 0 1 1 1 0 TMEM154 protein family DUF3827 PF12877.7 RLN78890.1 - 0.045 12.1 0.0 0.062 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) stn_TNFRSF12A PF12191.8 RLN78890.1 - 0.088 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain LRR_9 PF14580.6 RLN78890.1 - 0.2 11.2 0.1 0.31 10.5 0.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeat AGA2 PF17366.2 RLN78891.1 - 0.0032 17.1 0.1 0.031 14.0 0.0 2.2 2 0 0 2 2 2 1 A-agglutinin-binding subunit Aga2 APC_basic PF05956.11 RLN78891.1 - 0.019 14.4 0.8 0.025 14.1 0.8 1.1 1 0 0 1 1 1 0 APC basic domain PAP_central PF04928.17 RLN78892.1 - 2.3e-53 180.7 0.0 2.7e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Poly(A) polymerase central domain NTP_transf_2 PF01909.23 RLN78892.1 - 2.9e-07 30.7 0.0 6.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D5 PF17406.2 RLN78892.1 - 0.043 13.6 0.2 0.077 12.7 0.2 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 DNA_pol_B_palm PF14792.6 RLN78892.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase beta palm WD40 PF00400.32 RLN78904.1 - 1.6e-62 206.0 21.2 3.8e-08 33.9 0.1 8.8 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN78904.1 - 7.1e-21 74.3 0.9 0.0035 17.6 0.0 6.7 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RLN78904.1 - 7.4e-10 38.6 2.4 0.0001 21.8 0.3 4.9 2 2 2 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 RLN78904.1 - 1.3e-08 34.2 4.4 0.036 13.0 0.0 4.8 1 1 2 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RLN78904.1 - 1.1e-06 27.7 6.3 0.38 9.3 0.0 5.5 2 2 4 6 6 6 3 Nucleoporin Nup120/160 DUF5570 PF17731.1 RLN78904.1 - 0.0005 20.1 4.7 0.11 12.6 0.0 4.2 1 1 4 5 5 5 1 Family of unknown function (DUF5570) WD40_3 PF15911.5 RLN78904.1 - 0.0024 17.9 0.5 7.4 6.7 0.0 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat CEP19 PF14933.6 RLN78904.1 - 0.12 12.6 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 CEP19-like protein PKD PF00801.20 RLN78904.1 - 0.17 11.8 0.5 79 3.2 0.1 3.4 3 0 0 3 3 3 0 PKD domain Tom7 PF08038.12 RLN78905.1 - 2.2e-08 33.6 0.4 4.3e-08 32.7 0.4 1.5 1 0 0 1 1 1 1 TOM7 family SHIPPO-rpt PF07004.12 RLN78905.1 - 0.099 13.6 0.8 13 6.9 0.2 3.0 2 0 0 2 2 2 0 Sperm-tail PG-rich repeat Trp_oprn_chp PF09534.10 RLN78906.1 - 0.00039 20.3 1.7 0.00039 20.3 1.7 1.6 2 0 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Amnionless PF14828.6 RLN78906.1 - 0.0028 16.6 0.1 0.0035 16.2 0.1 1.2 1 0 0 1 1 1 1 Amnionless Wzy_C_2 PF11846.8 RLN78906.1 - 0.092 12.7 0.2 0.13 12.1 0.2 1.3 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal DUF4366 PF14283.6 RLN78906.1 - 0.33 11.0 4.7 1.6 8.7 4.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Plasmodium_Vir PF05795.11 RLN78906.1 - 0.38 10.1 1.4 0.46 9.8 1.4 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein eIF2A PF08662.11 RLN78907.1 - 1.1e-53 182.0 1.8 3.2e-49 167.4 0.8 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 RLN78907.1 - 8.4e-07 29.2 0.2 2.7 8.4 0.0 5.6 1 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 RLN78907.1 - 0.0005 18.2 0.1 0.0013 16.9 0.0 1.6 1 1 0 2 2 2 1 IKI3 family WD40 PF00400.32 RLN78907.1 - 0.00063 20.5 1.0 34 5.5 0.0 5.1 6 0 0 6 6 6 1 WD domain, G-beta repeat Lactonase PF10282.9 RLN78907.1 - 0.11 11.8 0.0 2.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller NIF PF03031.18 RLN78908.1 - 0.0096 15.7 0.0 0.073 12.8 0.0 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase HAD PF12710.7 RLN78908.1 - 0.11 12.9 1.0 1.7 9.0 0.0 2.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase zf-C2H2 PF00096.26 RLN78928.1 - 5.5e-12 45.4 18.6 0.0015 18.9 5.4 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RLN78928.1 - 6.8e-09 35.8 27.0 2.9e-05 24.3 4.1 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RLN78928.1 - 1.8e-08 34.5 17.1 0.0036 18.0 0.8 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 RLN78928.1 - 9.5e-06 25.8 4.7 0.00022 21.5 0.9 2.1 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 RLN78928.1 - 0.011 16.0 5.1 0.27 11.6 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 RLN78928.1 - 0.031 14.9 8.2 0.31 11.7 1.4 2.5 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-TRAF PF02176.18 RLN78928.1 - 0.15 12.8 12.9 0.099 13.3 3.8 2.4 1 1 2 3 3 3 0 TRAF-type zinc finger zf-met PF12874.7 RLN78928.1 - 0.29 11.6 6.3 0.88 10.1 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Hydrolase_4 PF12146.8 RLN78929.1 - 1.1e-11 44.4 2.3 0.0001 21.6 0.2 3.3 2 2 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN78929.1 - 1.2e-09 39.1 9.0 0.0021 18.7 0.7 5.0 2 2 1 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN78929.1 - 1.2e-08 35.0 0.2 0.00084 19.1 0.1 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF3525 PF12039.8 RLN78929.1 - 1.6e-05 23.8 0.0 0.15 10.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3525) DUF2920 PF11144.8 RLN78929.1 - 0.00051 19.3 0.5 0.85 8.7 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2920) FACT-Spt16_Nlob PF14826.6 RLN78929.1 - 0.012 15.4 0.0 7.3 6.4 0.0 2.3 2 0 0 2 2 2 0 FACT complex subunit SPT16 N-terminal lobe domain MCR_alpha PF02249.17 RLN78929.1 - 0.16 12.4 4.4 9.1 6.8 0.3 2.6 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain DUF4778 PF16008.5 RLN78929.1 - 0.21 11.6 2.5 2.4 8.1 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) tRNA-synt_1b PF00579.25 RLN78931.1 - 1.3e-71 241.3 0.0 1.7e-71 240.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) NCD1 PF04904.13 RLN78931.1 - 0.18 11.8 0.1 15 5.7 0.0 2.4 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) Ion_trans PF00520.31 RLN78932.1 - 7.5e-17 61.4 12.5 1.6e-16 60.3 12.5 1.5 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RLN78932.1 - 3e-14 52.7 3.5 1e-13 51.0 3.5 1.9 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.18 RLN78932.1 - 6.5e-10 39.1 0.0 1.9e-08 34.3 0.0 2.7 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit DUF3671 PF12420.8 RLN78932.1 - 4.5 7.4 4.2 2.9 8.0 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function Mannosyl_trans3 PF11051.8 RLN78933.1 - 1.2e-29 103.5 0.0 2.5e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 RLN78933.1 - 0.013 15.5 0.1 0.022 14.8 0.1 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.8 RLN78934.1 - 1.8e-73 247.3 0.0 4.8e-26 91.7 0.0 3.7 3 1 0 3 3 3 3 Mannosyltransferase putative Nucleotid_trans PF03407.16 RLN78934.1 - 0.0056 16.7 4.8 4.7 7.1 0.5 3.7 3 0 0 3 3 3 2 Nucleotide-diphospho-sugar transferase BA14K PF07886.11 RLN78934.1 - 0.14 12.0 1.0 20 5.2 0.2 2.5 2 0 0 2 2 2 0 BA14K-like protein SBP_bac_11 PF13531.6 RLN78934.1 - 0.16 11.7 7.3 0.33 10.6 0.7 3.0 4 0 0 4 4 4 0 Bacterial extracellular solute-binding protein Glyoxalase PF00903.25 RLN78956.1 - 0.0014 18.8 0.1 0.0023 18.1 0.1 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Imm27 PF15590.6 RLN78956.1 - 0.072 12.9 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 27 WEMBL PF05701.11 RLN78956.1 - 0.23 10.1 0.0 0.28 9.8 0.0 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Pantoate_transf PF02548.15 RLN78957.1 - 3.6e-53 180.6 0.2 2.3e-38 132.0 0.0 2.0 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase Methyltr_RsmF_N PF17125.5 RLN78958.1 - 0.035 14.6 0.1 9.2 6.8 0.0 2.3 2 0 0 2 2 2 0 N-terminal domain of 16S rRNA methyltransferase RsmF P_C10 PF14974.6 RLN78959.1 - 3.6e-10 39.9 0.0 8.2e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Protein C10 I-set PF07679.16 RLN78959.1 - 2.3e-06 27.6 0.0 9.5e-06 25.6 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RLN78959.1 - 2.6e-06 27.9 0.0 7.7e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain WD40 PF00400.32 RLN78959.1 - 3.4e-06 27.7 2.2 0.00019 22.1 0.1 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat ig PF00047.25 RLN78959.1 - 0.00012 22.2 0.0 0.00054 20.1 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain Lar_restr_allev PF14354.6 RLN78959.1 - 0.017 15.5 0.4 0.044 14.2 0.4 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar ANAPC4_WD40 PF12894.7 RLN78959.1 - 0.025 14.9 0.0 4.7 7.6 0.0 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain BiPBP_C PF06832.12 RLN78959.1 - 0.053 13.6 0.0 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family Ig_2 PF13895.6 RLN78959.1 - 0.083 13.2 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin domain MCM_OB PF17207.3 RLN78959.1 - 0.25 11.2 1.6 0.41 10.5 0.2 1.9 2 0 0 2 2 2 0 MCM OB domain zf-RING_7 PF02591.15 RLN78959.1 - 8.6 6.6 6.9 3.2 8.0 1.9 2.7 3 0 0 3 3 3 0 C4-type zinc ribbon domain STI1 PF17830.1 RLN78960.1 - 6.4e-12 45.2 10.5 9.7e-07 28.6 0.8 2.9 3 0 0 3 3 3 2 STI1 domain FlgN PF05130.12 RLN78960.1 - 0.013 16.0 2.2 0.013 16.0 2.2 2.7 3 0 0 3 3 3 0 FlgN protein eIF3_N PF09440.10 RLN78960.1 - 4.6 7.7 8.6 0.27 11.7 1.7 2.5 2 2 0 2 2 2 0 eIF3 subunit 6 N terminal domain Prefoldin_2 PF01920.20 RLN78961.1 - 2.4e-13 49.9 3.7 2.4e-13 49.9 3.7 1.9 2 1 0 2 2 2 1 Prefoldin subunit Pup_ligase PF03136.15 RLN78961.1 - 0.029 13.4 0.3 0.036 13.1 0.3 1.2 1 0 0 1 1 1 0 Pup-ligase protein Spore_III_AB PF09548.10 RLN78961.1 - 0.072 13.2 0.3 0.074 13.2 0.3 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) SNF2_N PF00176.23 RLN78962.1 - 2.4e-77 260.0 0.0 3.9e-77 259.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN78962.1 - 2.4e-18 66.5 0.0 5.3e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 RLN78962.1 - 1.7e-10 40.5 6.4 1.7e-10 40.5 6.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN78962.1 - 8.6e-09 35.2 4.8 8.6e-09 35.2 4.8 2.2 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RLN78962.1 - 1.2e-08 34.6 5.9 1.2e-08 34.6 5.9 2.6 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 ResIII PF04851.15 RLN78962.1 - 4.1e-08 33.4 0.0 7.5e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 RLN78962.1 - 1e-07 32.1 8.5 1e-07 32.1 8.5 3.0 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 RLN78962.1 - 1.7e-07 31.0 8.0 1.7e-07 31.0 8.0 2.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN78962.1 - 3.2e-07 30.1 9.3 3.2e-07 30.1 9.3 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 RLN78962.1 - 2.6e-06 27.3 0.0 7.2e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.6 RLN78962.1 - 1.4e-05 25.0 7.5 1.4e-05 25.0 7.5 2.8 3 0 0 3 3 2 1 RING-type zinc-finger ERCC3_RAD25_C PF16203.5 RLN78962.1 - 0.00037 19.8 0.0 0.0007 18.9 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-RanBP PF00641.18 RLN78962.1 - 0.00045 19.5 2.1 0.0019 17.4 2.1 2.1 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others TetR_C_2 PF08361.11 RLN78962.1 - 0.17 12.0 0.0 0.54 10.4 0.0 1.8 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region zf-RING_6 PF14835.6 RLN78962.1 - 0.23 11.4 1.9 0.71 9.8 1.9 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 RLN78962.1 - 1 9.2 5.3 3.3 7.6 5.3 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 RLN78962.1 - 1 9.2 4.3 3.1 7.7 4.3 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1644 PF07800.12 RLN78962.1 - 1.7 8.7 5.4 2.1 8.4 2.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) FYDLN_acid PF09538.10 RLN78962.1 - 3.9 8.2 6.4 1.2 9.9 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Radical_SAM PF04055.21 RLN78963.1 - 3.8e-29 102.2 0.0 1.5e-28 100.2 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Cnn_1N PF07989.11 RLN78964.1 - 0.00015 21.8 2.3 0.00015 21.8 2.3 6.3 4 1 3 7 7 7 2 Centrosomin N-terminal motif 1 CTP_transf_like PF01467.26 RLN78966.1 - 1.9e-09 37.9 0.0 3.5e-09 37.0 0.0 1.5 1 1 0 1 1 1 1 Cytidylyltransferase-like Pox_A_type_inc PF04508.12 RLN78966.1 - 0.0005 19.8 0.9 0.0015 18.3 0.9 1.8 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat FtsK_alpha PF17854.1 RLN78966.1 - 0.042 14.0 0.1 3.5 7.8 0.0 2.3 2 0 0 2 2 2 0 FtsK alpha domain PGAP1 PF07819.13 RLN78980.1 - 0.02 14.6 0.1 0.047 13.4 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_6 PF12697.7 RLN78980.1 - 0.066 13.8 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 RLN78980.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.15 RLN78980.1 - 0.16 11.1 0.2 0.28 10.3 0.2 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 RLN78981.1 - 0.031 14.0 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 RLN78981.1 - 0.09 13.4 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 RLN78981.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.15 RLN78981.1 - 0.19 10.8 0.2 0.34 10.0 0.2 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PH PF00169.29 RLN78982.1 - 0.00016 22.1 0.0 0.00028 21.4 0.0 1.4 1 0 0 1 1 1 1 PH domain Cytochrom_B562 PF07361.11 RLN78982.1 - 0.73 10.5 4.4 0.58 10.8 1.3 2.4 2 0 0 2 2 2 0 Cytochrome b562 Pkinase PF00069.25 RLN78983.1 - 2.5e-40 138.5 0.0 1.2e-30 106.8 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN78983.1 - 1.3e-10 41.0 0.0 0.00022 20.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase CDC50 PF03381.15 RLN78984.1 - 5.4e-85 285.3 0.0 8.4e-85 284.7 0.0 1.3 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family RRM_1 PF00076.22 RLN78985.1 - 5.5e-07 29.3 0.0 0.00026 20.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN78985.1 - 0.072 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif NPR3 PF03666.13 RLN78985.1 - 5 5.8 7.5 5.6 5.6 7.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 RLN78985.1 - 9.6 4.9 6.0 10 4.7 6.0 1.1 1 0 0 1 1 1 0 Presenilin PI3_PI4_kinase PF00454.27 RLN78986.1 - 1.2e-33 117.0 0.8 1.2e-31 110.5 0.4 2.7 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 RLN78986.1 - 5.7e-06 25.9 0.1 1.7e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 RLN78986.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) RSN1_TM PF13967.6 RLN78986.1 - 0.19 11.5 1.8 0.66 9.7 1.8 1.9 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport DUF4632 PF15451.6 RLN78986.1 - 3.2 7.9 5.0 1.1 9.4 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4632) BatA PF07584.11 RLN78986.1 - 5.2 7.5 13.0 1.1 9.7 3.2 2.8 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal Vps39_2 PF10367.9 RLN78987.1 - 5e-22 78.4 0.0 3.2e-21 75.8 0.0 2.4 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 RLN78987.1 - 1.5e-16 60.6 0.2 6.7e-16 58.5 0.2 2.3 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 RLN78987.1 - 5e-05 23.0 0.0 0.0029 17.3 0.0 2.2 2 0 0 2 2 2 1 CNH domain Rsm1 PF08600.10 RLN78987.1 - 0.13 12.4 0.1 8.7 6.6 0.0 2.8 2 0 0 2 2 2 0 Rsm1-like RCC1 PF00415.18 RLN78988.1 - 2.5e-44 149.7 21.0 3.5e-12 46.7 0.2 7.6 7 2 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat WW PF00397.26 RLN78988.1 - 3e-26 91.2 28.3 2.9e-07 30.4 1.0 6.7 6 0 0 6 6 6 5 WW domain RCC1_2 PF13540.6 RLN78988.1 - 2.2e-18 65.5 38.1 3.8e-07 29.7 1.0 7.4 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.27 RLN78988.1 - 3.1e-08 32.7 33.3 0.026 14.3 0.5 7.8 6 0 0 6 6 6 5 IQ calmodulin-binding motif SAP PF02037.27 RLN78988.1 - 0.088 12.6 4.4 0.038 13.7 0.8 2.3 2 0 0 2 2 2 0 SAP domain Glyco_hyd_101C PF17451.2 RLN78988.1 - 0.51 10.6 8.5 16 5.8 0.3 4.9 4 1 1 5 5 5 0 Glycosyl hydrolase 101 beta sandwich domain OKR_DC_1_N PF03709.15 RLN78989.1 - 0.00051 20.3 0.0 25 5.2 0.0 4.2 3 0 0 3 3 3 2 Orn/Lys/Arg decarboxylase, N-terminal domain EGF_2 PF07974.13 RLN78989.1 - 0.0033 17.8 2.6 0.0065 16.8 2.6 1.5 1 0 0 1 1 1 1 EGF-like domain HTH_11 PF08279.12 RLN78989.1 - 0.0042 17.0 6.5 84 3.2 0.0 5.5 5 0 0 5 5 5 0 HTH domain Laminin_EGF PF00053.24 RLN78989.1 - 0.023 14.8 2.6 0.045 13.9 2.6 1.4 1 0 0 1 1 1 0 Laminin EGF domain EGF_Tenascin PF18720.1 RLN78989.1 - 0.69 10.0 5.0 1.8 8.7 5.0 1.7 1 0 0 1 1 1 0 Tenascin EGF domain Elicitin PF00964.17 RLN79012.1 - 3.6e-21 75.1 0.5 4.6e-21 74.7 0.5 1.1 1 0 0 1 1 1 1 Elicitin CBM9_1 PF06452.11 RLN79013.1 - 0.00048 20.1 0.4 0.00048 20.1 0.4 1.7 2 0 0 2 2 2 1 Carbohydrate family 9 binding domain-like CBM9_2 PF16011.5 RLN79013.1 - 0.0033 17.2 0.4 0.012 15.4 0.1 1.8 2 0 0 2 2 2 1 Carbohydrate-binding family 9 SSF PF00474.17 RLN79014.1 - 2.2e-88 296.9 14.8 2.2e-88 296.9 14.8 1.8 2 0 0 2 2 2 1 Sodium:solute symporter family MscL PF01741.18 RLN79014.1 - 0.73 10.1 4.0 20 5.5 0.1 3.4 3 0 0 3 3 3 0 Large-conductance mechanosensitive channel, MscL Pkinase_Tyr PF07714.17 RLN79027.1 - 1.5e-13 50.7 0.0 2.4e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN79027.1 - 5.1e-11 42.4 0.0 1e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Aminotran_5 PF00266.19 RLN79027.1 - 4.1e-08 32.6 0.0 7.8e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V SKG6 PF08693.10 RLN79027.1 - 0.38 10.2 4.2 0.8 9.2 4.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Utp14 PF04615.13 RLN79028.1 - 2.8e-158 528.8 70.3 2.8e-158 528.8 70.3 2.0 1 1 0 2 2 2 1 Utp14 protein Elicitin PF00964.17 RLN79029.1 - 4.1e-08 33.2 0.2 9.2e-08 32.1 0.1 1.6 1 1 0 1 1 1 1 Elicitin tRNA-synt_2d PF01409.20 RLN79030.1 - 2.4e-20 73.1 0.0 2.6e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) HTH_30 PF13556.6 RLN79030.1 - 0.015 15.1 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Mito_carr PF00153.27 RLN79031.1 - 1.3e-18 66.7 0.1 1.6e-18 66.4 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein Glyco_transf_8 PF01501.20 RLN79031.1 - 0.036 13.6 0.0 0.042 13.4 0.0 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 8 Form-deh_trans PF09163.11 RLN79031.1 - 0.075 12.8 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane TPR_1 PF00515.28 RLN79032.1 - 1.8e-52 173.1 7.7 3.3e-07 29.8 0.0 10.2 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_2 PF07719.17 RLN79032.1 - 8.4e-47 153.6 5.2 0.00016 21.5 0.0 10.2 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 RLN79032.1 - 2.9e-40 133.1 5.3 2.9e-05 23.9 0.0 10.1 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_17 PF13431.6 RLN79032.1 - 3.5e-27 92.8 11.6 0.00041 20.5 0.0 9.6 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 RLN79032.1 - 4.2e-24 83.9 11.1 4.3e-06 26.3 0.0 10.2 6 3 4 10 10 10 5 TPR repeat TPR_19 PF14559.6 RLN79032.1 - 9.3e-23 80.5 1.1 3.7e-06 27.4 0.0 6.0 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 RLN79032.1 - 2.5e-22 78.9 7.1 0.0005 20.3 0.1 7.3 4 3 2 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 RLN79032.1 - 9.7e-22 75.8 0.9 0.014 16.2 0.0 8.9 4 2 5 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 RLN79032.1 - 6.2e-19 68.4 0.2 0.016 15.9 0.1 6.8 2 2 5 8 8 8 7 Tetratricopeptide repeat TPR_6 PF13174.6 RLN79032.1 - 1.7e-17 62.8 2.4 0.58 10.9 0.0 9.2 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN79032.1 - 7e-14 50.8 6.6 0.047 13.7 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN79032.1 - 2.7e-11 43.4 3.0 0.015 15.5 0.3 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN79032.1 - 4.6e-11 42.8 7.5 0.0017 18.6 2.2 3.7 2 2 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 RLN79032.1 - 2.2e-07 30.4 2.7 0.049 12.8 0.1 3.8 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_21 PF09976.9 RLN79032.1 - 4.3e-07 29.8 1.6 0.018 14.7 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat-like domain SNAP PF14938.6 RLN79032.1 - 0.00021 20.8 6.2 1.3 8.4 0.0 4.6 2 2 2 4 4 4 1 Soluble NSF attachment protein, SNAP ChAPs PF09295.10 RLN79032.1 - 0.00048 19.2 0.3 0.0099 14.9 0.0 2.6 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 RLN79032.1 - 0.01 16.2 0.0 3.9 7.9 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF1965 PF09248.10 RLN79032.1 - 0.017 14.9 0.2 0.59 9.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1965) BTAD PF03704.17 RLN79032.1 - 0.026 15.0 0.9 2.4 8.6 0.0 3.4 3 1 0 3 3 3 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 RLN79032.1 - 0.033 14.3 0.0 27 4.9 0.0 3.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.8 RLN79032.1 - 0.075 11.9 0.9 11 4.7 0.0 3.1 2 1 2 4 4 4 0 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 RLN79032.1 - 0.15 12.0 7.3 8.3 6.4 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat MIT PF04212.18 RLN79032.1 - 0.68 10.0 5.5 7.5 6.7 0.1 4.3 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain Elicitin PF00964.17 RLN79033.1 - 3.3e-07 30.3 0.2 6.9e-07 29.3 0.2 1.5 1 0 0 1 1 1 1 Elicitin Fim-adh_lectin PF09222.10 RLN79033.1 - 0.0085 15.6 0.1 0.018 14.5 0.1 1.5 1 0 0 1 1 1 1 Fimbrial adhesin F17-AG, lectin domain Elicitin PF00964.17 RLN79034.1 - 2.3e-06 27.6 0.2 7e-06 26.0 0.1 1.9 1 1 0 1 1 1 1 Elicitin Brix PF04427.18 RLN79035.1 - 9e-44 149.9 0.1 1.7e-43 149.0 0.1 1.4 1 0 0 1 1 1 1 Brix domain PBP_sp32 PF07222.12 RLN79035.1 - 1.6 8.1 8.4 2.8 7.3 8.4 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 AP-5_subunit_s1 PF15001.6 RLN79035.1 - 1.9 8.4 5.7 4.6 7.2 5.7 1.6 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 DUF5308 PF17233.2 RLN79035.1 - 3.6 7.8 7.3 3.5 7.8 5.6 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5308) MNNL PF07657.13 RLN79036.1 - 0.27 11.3 5.4 0.7 10.0 5.4 1.7 1 0 0 1 1 1 0 N terminus of Notch ligand Elicitin PF00964.17 RLN79037.1 - 8.3e-07 29.0 1.0 8.3e-07 29.0 1.0 2.5 1 1 1 2 2 2 1 Elicitin Mito_carr PF00153.27 RLN79038.1 - 5e-20 71.2 0.5 1.2e-12 47.5 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein Cation_efflux PF01545.21 RLN79038.1 - 7.9e-19 68.2 0.5 8.4e-15 55.0 0.0 2.5 1 1 1 2 2 2 2 Cation efflux family ZT_dimer PF16916.5 RLN79038.1 - 0.00099 19.2 0.0 0.0032 17.5 0.0 1.9 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DNA_ligase_OB_2 PF14743.6 RLN79055.1 - 8.6e-27 93.0 0.0 1.9e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 DNA ligase OB-like domain BRCT PF00533.26 RLN79055.1 - 1.1e-15 57.7 0.0 0.0021 18.4 0.0 3.6 3 0 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 RLN79055.1 - 2.2e-14 53.1 0.8 5.9e-05 22.9 0.1 3.6 3 0 0 3 3 3 3 twin BRCT domain DNA_ligase_A_M PF01068.21 RLN79055.1 - 1.2e-11 44.7 0.0 5.6e-11 42.5 0.0 2.0 1 1 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 RLN79055.1 - 0.0057 17.0 0.0 0.035 14.4 0.0 2.2 1 1 0 1 1 1 1 RNA ligase TRAP_alpha PF03896.16 RLN79055.1 - 6.9 5.8 7.6 7.2 5.7 0.2 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit SET PF00856.28 RLN79056.1 - 1.7e-14 54.5 0.0 6.1e-14 52.8 0.0 1.8 1 1 0 1 1 1 1 SET domain SBF PF01758.16 RLN79057.1 - 9.6e-48 162.4 9.9 9.6e-48 162.4 9.9 2.1 1 1 1 2 2 2 1 Sodium Bile acid symporter family KASH PF10541.9 RLN79057.1 - 0.11 12.7 0.5 0.11 12.7 0.5 2.9 3 0 0 3 3 3 0 Nuclear envelope localisation domain DUF2208 PF09973.9 RLN79057.1 - 0.25 10.9 4.4 0.67 9.5 4.4 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Ras PF00071.22 RLN79058.1 - 3.5e-17 62.5 0.0 5.5e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN79058.1 - 9.4e-10 38.8 0.0 2.8e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN79058.1 - 0.0019 17.7 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RLN79058.1 - 0.02 14.2 0.0 0.05 13.0 0.0 1.6 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA PF00004.29 RLN79059.1 - 8.6e-52 175.1 0.1 1.8e-40 138.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Peptidase_M3 PF01432.20 RLN79059.1 - 4.7e-11 42.6 0.0 7.7e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 AAA_16 PF13191.6 RLN79059.1 - 2.4e-10 41.0 0.2 0.0011 19.4 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_lid_3 PF17862.1 RLN79059.1 - 6.2e-10 38.7 0.1 2.6e-09 36.8 0.1 2.1 1 1 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 RLN79059.1 - 4.3e-08 32.8 0.0 0.0018 17.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 RLN79059.1 - 9.7e-08 32.1 0.0 0.00063 19.8 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RLN79059.1 - 3.3e-07 30.6 0.1 2e-05 24.8 0.0 2.9 2 1 1 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 RLN79059.1 - 1e-06 29.0 3.8 0.012 15.8 0.5 4.4 2 2 0 3 3 3 1 AAA domain RuvB_N PF05496.12 RLN79059.1 - 1.9e-06 27.7 0.1 0.05 13.4 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 RLN79059.1 - 1.6e-05 24.6 0.0 0.057 13.1 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain RNA_helicase PF00910.22 RLN79059.1 - 4.6e-05 23.8 0.0 0.049 14.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase TsaE PF02367.17 RLN79059.1 - 6.1e-05 23.0 0.0 0.48 10.4 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 RLN79059.1 - 6.8e-05 22.9 0.0 0.1 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 RLN79059.1 - 8e-05 22.6 0.2 0.091 12.7 0.1 3.1 2 1 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 RLN79059.1 - 0.00015 21.2 0.1 0.0042 16.5 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 RLN79059.1 - 0.00016 21.1 0.1 2.4 7.6 0.0 3.4 2 1 0 3 3 3 1 Bacterial TniB protein ABC_tran PF00005.27 RLN79059.1 - 0.00018 22.0 0.3 0.0086 16.6 0.0 2.7 2 0 0 2 2 2 1 ABC transporter IstB_IS21 PF01695.17 RLN79059.1 - 0.0002 21.1 0.0 0.17 11.6 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 RLN79059.1 - 0.0003 21.0 0.0 0.029 14.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 RLN79059.1 - 0.00036 19.8 0.0 0.56 9.3 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_7 PF12775.7 RLN79059.1 - 0.00058 19.4 0.0 0.074 12.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase PF06745.13 RLN79059.1 - 0.0011 18.4 0.0 0.022 14.1 0.0 2.4 2 0 0 2 2 2 1 KaiC Zeta_toxin PF06414.12 RLN79059.1 - 0.0019 17.5 0.0 2.5 7.3 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_24 PF13479.6 RLN79059.1 - 0.0026 17.5 0.1 0.46 10.2 0.0 2.8 2 2 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 RLN79059.1 - 0.0041 17.1 0.5 2.1 8.2 0.0 3.1 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_23 PF13476.6 RLN79059.1 - 0.0062 17.1 0.0 0.29 11.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 RLN79059.1 - 0.0073 16.3 0.0 0.99 9.4 0.0 2.6 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Bac_DnaA PF00308.18 RLN79059.1 - 0.012 15.4 0.0 0.59 9.9 0.0 2.5 3 0 0 3 3 2 0 Bacterial dnaA protein AAA_25 PF13481.6 RLN79059.1 - 0.016 14.8 2.2 3 7.4 0.0 3.0 2 1 1 3 3 3 0 AAA domain DUF815 PF05673.13 RLN79059.1 - 0.02 14.1 0.1 0.69 9.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Rad17 PF03215.15 RLN79059.1 - 0.021 14.7 0.0 0.078 12.9 0.0 1.9 2 0 0 2 2 1 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 RLN79059.1 - 0.022 14.9 0.0 15 5.7 0.0 3.2 4 0 0 4 4 2 0 Sigma-54 interaction domain PhoH PF02562.16 RLN79059.1 - 0.028 13.9 0.1 7.6 5.9 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 RLN79059.1 - 0.037 13.8 0.0 0.72 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RLN79059.1 - 0.048 14.2 0.0 0.29 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.10 RLN79059.1 - 0.059 13.4 0.0 6.5 6.8 0.0 2.6 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_3 PF07726.11 RLN79059.1 - 0.089 12.7 0.0 1.6 8.6 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 RLN79059.1 - 0.12 12.8 0.5 0.76 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 RLN79059.1 - 0.16 11.1 0.2 5.3 6.1 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_19 PF13245.6 RLN79059.1 - 0.17 12.2 0.3 1.8 8.9 0.0 2.7 2 1 1 3 3 2 0 AAA domain RPEL PF02755.15 RLN79060.1 - 9.6e-15 53.7 11.2 0.00012 21.6 0.1 4.8 4 0 0 4 4 4 4 RPEL repeat Mto2_bdg PF12808.7 RLN79060.1 - 3.7 7.9 9.3 0.61 10.4 1.2 3.2 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region FAD_binding_1 PF00667.20 RLN79081.1 - 1.3e-39 136.1 0.0 6e-37 127.4 0.0 2.5 2 0 0 2 2 2 2 FAD binding domain Flavodoxin_1 PF00258.25 RLN79081.1 - 7.4e-26 91.1 0.0 1.1e-25 90.5 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 RLN79081.1 - 0.001 19.7 0.1 0.0072 17.0 0.0 2.3 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain Aldedh PF00171.22 RLN79082.1 - 1.7e-119 399.3 0.5 2.3e-119 399.0 0.5 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HTH_Tnp_Tc3_1 PF11427.8 RLN79082.1 - 2.6e-10 40.0 0.0 9.5e-10 38.2 0.0 2.0 2 0 0 2 2 2 1 Tc3 transposase DUF1487 PF07368.11 RLN79082.1 - 1.5e-06 27.8 0.0 1.1e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) HTH_38 PF13936.6 RLN79082.1 - 2.6e-06 27.1 1.2 3.5e-06 26.7 0.2 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.6 RLN79082.1 - 0.0021 18.6 1.3 0.016 15.8 0.2 2.3 1 1 1 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 RLN79082.1 - 0.0069 16.2 1.4 0.014 15.2 0.1 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 RLN79082.1 - 0.007 16.4 0.1 0.025 14.6 0.1 2.0 1 1 0 1 1 1 1 Winged helix-turn helix HTH_24 PF13412.6 RLN79082.1 - 0.12 11.9 0.1 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding zf-DNL PF05180.12 RLN79083.1 - 2.1e-29 101.2 0.1 3.1e-29 100.7 0.1 1.3 1 0 0 1 1 1 1 DNL zinc finger DUF4805 PF16063.5 RLN79083.1 - 0.067 12.5 0.6 0.083 12.2 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) EutQ PF06249.12 RLN79084.1 - 0.16 11.8 0.1 0.18 11.6 0.1 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ AA_kinase PF00696.28 RLN79085.1 - 2.5e-14 53.5 0.1 4.2e-14 52.7 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family Acetyltransf_1 PF00583.25 RLN79085.1 - 1.8e-07 31.4 0.0 3.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RLN79085.1 - 1.4e-05 25.4 0.0 2.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RLN79085.1 - 8.9e-05 22.4 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_9 PF12781.7 RLN79085.1 - 0.04 13.0 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 ATP-binding dynein motor region EGF_2 PF07974.13 RLN79086.1 - 0.0042 17.4 5.4 0.0087 16.4 5.4 1.5 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 RLN79086.1 - 0.011 16.4 3.4 0.023 15.3 3.4 1.6 1 0 0 1 1 1 0 Human growth factor-like EGF EB PF01683.18 RLN79086.1 - 0.12 12.7 2.0 0.34 11.2 1.0 2.0 2 0 0 2 2 2 0 EB module XendoU PF09412.10 RLN79087.1 - 5.2e-36 124.2 0.1 7.8e-36 123.6 0.1 1.2 1 0 0 1 1 1 1 Endoribonuclease XendoU IQ PF00612.27 RLN79087.1 - 0.045 13.6 1.2 0.11 12.3 1.2 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif XendoU PF09412.10 RLN79088.1 - 1.6e-40 139.0 0.0 2.2e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease XendoU HECT PF00632.25 RLN79089.1 - 2.1e-69 234.3 0.0 7.2e-69 232.6 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Actin PF00022.19 RLN79090.1 - 2.6e-16 59.2 0.0 3.1e-16 59.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 RLN79090.1 - 0.064 12.1 0.0 0.077 11.8 0.0 1.1 1 0 0 1 1 1 0 MreB/Mbl protein DUF995 PF06191.12 RLN79090.1 - 0.065 12.9 0.1 0.088 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF995) PQQ_3 PF13570.6 RLN79090.1 - 0.085 13.4 0.1 1.4 9.5 0.0 2.5 2 1 0 2 2 2 0 PQQ-like domain HECT PF00632.25 RLN79091.1 - 9.7e-67 225.6 0.0 1.3e-66 225.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zinc_ribbon_2 PF13240.6 RLN79091.1 - 0.044 13.5 2.8 0.083 12.6 2.8 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 RLN79091.1 - 0.056 13.5 0.5 0.11 12.5 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 RLN79091.1 - 0.89 9.1 8.2 1.2 8.8 0.1 3.9 5 0 0 5 5 5 0 TFIIB zinc-binding HECT PF00632.25 RLN79092.1 - 3.3e-67 227.2 0.0 4.3e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zinc_ribbon_15 PF17032.5 RLN79092.1 - 0.063 14.0 0.2 0.13 13.0 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon family DZR PF12773.7 RLN79092.1 - 0.15 12.1 0.4 0.3 11.1 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon HSP70 PF00012.20 RLN79093.1 - 1.2e-149 499.3 9.0 1.6e-149 498.9 9.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN79093.1 - 4.1e-15 55.4 0.2 8e-15 54.5 0.2 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Big_3 PF07523.12 RLN79093.1 - 0.0046 17.2 0.7 0.014 15.6 0.2 2.1 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 3) Yip1 PF04893.17 RLN79094.1 - 1e-06 28.5 13.8 1.4e-06 28.1 13.8 1.1 1 0 0 1 1 1 1 Yip1 domain DUF2070 PF09843.9 RLN79094.1 - 5 5.3 9.4 6.1 5.0 9.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FHA PF00498.26 RLN79095.1 - 4.6e-05 23.7 0.0 8.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-C2H2_4 PF13894.6 RLN79095.1 - 0.053 14.4 1.1 0.12 13.3 1.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger ThiP_synth PF10120.9 RLN79096.1 - 0.014 15.0 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 Thiamine-phosphate synthase Ysc84 PF04366.12 RLN79117.1 - 1.3e-30 105.8 1.8 2.3e-30 105.0 1.0 1.8 2 0 0 2 2 2 1 Las17-binding protein actin regulator YL1_C PF08265.11 RLN79117.1 - 0.077 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain LNS2 PF08235.13 RLN79133.1 - 4e-37 127.9 0.0 6.6e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) HA PF03457.14 RLN79134.1 - 3.2e-18 65.8 1.7 6.8e-07 29.5 0.4 3.3 3 0 0 3 3 3 3 Helicase associated domain Pkinase_Tyr PF07714.17 RLN79135.1 - 2.6e-53 181.0 0.0 3.6e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN79135.1 - 1.7e-50 171.9 0.0 2.5e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF1382 PF07131.11 RLN79135.1 - 0.054 13.5 0.1 2.7 8.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1382) Malate_synthase PF01274.22 RLN79136.1 - 5.4e-203 675.0 0.0 6.2e-203 674.8 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Glyco_hydro_30 PF02055.16 RLN79148.1 - 5e-102 341.4 2.1 6.3e-102 341.1 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 RLN79148.1 - 1.1e-09 38.4 0.3 2.3e-09 37.3 0.3 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 RLN79149.1 - 7e-107 357.4 1.9 9.1e-107 357.0 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 RLN79149.1 - 1.2e-12 47.8 5.0 2.8e-12 46.7 5.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain DUF1966 PF09260.11 RLN79149.1 - 0.049 13.9 1.3 0.071 13.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1966) Glyco_hydr_30_2 PF14587.6 RLN79149.1 - 0.064 12.8 0.4 0.23 11.0 0.1 1.8 2 0 0 2 2 2 0 O-Glycosyl hydrolase family 30 zf-H2C2_2 PF13465.6 RLN79150.1 - 1.9 9.0 3.3 42 4.8 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double domain Pkinase_Tyr PF07714.17 RLN79167.1 - 3.5e-32 111.7 0.0 5.5e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN79167.1 - 5.8e-29 101.3 0.0 1.1e-28 100.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF3430 PF11912.8 RLN79167.1 - 0.014 15.5 9.5 0.033 14.2 3.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3430) Pkinase PF00069.25 RLN79168.1 - 3.5e-49 167.5 0.0 4.6e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN79168.1 - 1.2e-44 152.5 0.0 1.5e-44 152.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN79168.1 - 0.028 13.8 0.1 0.04 13.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 RLN79170.1 - 2.7e-18 65.6 0.0 4e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RLN79170.1 - 0.0084 15.7 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 RLN79170.1 - 0.05 13.8 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter RRM_8 PF11835.8 RLN79170.1 - 0.12 12.6 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 RRM-like domain zf-TAZ PF02135.16 RLN79171.1 - 4.4e-24 84.7 36.5 5.6e-15 55.6 15.3 5.5 5 1 0 5 5 5 2 TAZ zinc finger HAT_KAT11 PF08214.11 RLN79171.1 - 1.9e-23 83.3 7.9 5e-22 78.7 2.7 3.2 2 1 0 2 2 2 1 Histone acetylation protein Bromodomain PF00439.25 RLN79171.1 - 2.2e-18 66.1 0.1 1.2e-17 63.7 0.1 2.3 2 0 0 2 2 2 1 Bromodomain ZZ PF00569.17 RLN79171.1 - 4.9e-10 39.1 8.3 4.9e-10 39.1 8.3 4.0 4 0 0 4 4 4 1 Zinc finger, ZZ type KIX_2 PF16987.5 RLN79171.1 - 1.4e-06 28.2 0.3 1.4e-06 28.2 0.3 2.6 2 0 0 2 2 2 1 KIX domain PHD PF00628.29 RLN79171.1 - 0.0002 21.2 0.7 0.0002 21.2 0.7 5.3 4 1 0 4 4 4 1 PHD-finger DUF902 PF06001.13 RLN79171.1 - 0.0057 17.1 6.3 0.015 15.8 6.3 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF902) KIX PF02172.16 RLN79171.1 - 0.015 15.5 0.0 0.11 12.8 0.0 2.6 1 0 0 1 1 1 0 KIX domain GCP_N_terminal PF17681.1 RLN79171.1 - 0.028 14.0 0.3 0.076 12.6 0.3 1.7 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal Bestrophin PF01062.21 RLN79172.1 - 0.00052 19.5 0.1 0.00065 19.2 0.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Filamin PF00630.19 RLN79174.1 - 5.1e-64 213.6 0.0 2.9e-14 53.7 0.0 9.2 10 0 0 10 10 10 6 Filamin/ABP280 repeat PA14 PF07691.12 RLN79174.1 - 1.5e-32 112.4 0.0 3.7e-14 52.8 0.0 3.8 3 0 0 3 3 3 3 PA14 domain Invasin_D3 PF09134.10 RLN79174.1 - 3e-11 43.5 19.2 0.0046 17.2 0.4 8.2 8 0 0 8 8 8 4 Invasin, domain 3 Calx-beta PF03160.14 RLN79174.1 - 2.6e-07 30.7 0.0 8.3e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 Calx-beta domain Cadherin_5 PF17892.1 RLN79174.1 - 3.8e-06 26.8 1.5 0.07 13.1 0.2 4.3 4 0 0 4 4 4 2 Cadherin-like domain Y_Y_Y PF07495.13 RLN79174.1 - 0.0049 16.8 0.2 6.6 6.8 0.1 4.3 5 0 0 5 5 5 1 Y_Y_Y domain YtkA PF13115.6 RLN79174.1 - 0.012 16.2 0.0 28 5.4 0.0 4.0 3 0 0 3 3 3 0 YtkA-like PPC PF04151.15 RLN79174.1 - 0.11 13.6 9.8 1.9 9.6 1.6 5.7 5 1 1 6 6 6 0 Bacterial pre-peptidase C-terminal domain DUF824 PF05688.11 RLN79174.1 - 0.15 11.9 1.3 14 5.6 0.0 3.6 3 0 0 3 3 3 0 Salmonella repeat of unknown function (DUF824) Big_1 PF02369.16 RLN79174.1 - 1.6 8.8 17.3 0.24 11.4 0.7 7.2 8 1 1 9 9 9 0 Bacterial Ig-like domain (group 1) FAM184 PF15665.5 RLN79175.1 - 0.00017 21.4 0.3 0.00034 20.5 0.3 1.4 2 0 0 2 2 2 1 Family with sequence similarity 184, A and B Metallophos PF00149.28 RLN79175.1 - 0.00028 21.4 0.0 0.0079 16.7 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Fibrillarin PF01269.17 RLN79176.1 - 3.3e-26 91.8 0.0 4.1e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin FSH1 PF03959.13 RLN79195.1 - 7.8e-38 130.3 0.0 9e-38 130.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 RLN79195.1 - 0.0095 15.8 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 RLN79195.1 - 0.029 14.3 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal SAP130_C PF16014.5 RLN79196.1 - 4 6.4 9.7 5.6 6.0 9.7 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Pro_isomerase PF00160.21 RLN79197.1 - 3.4e-39 134.6 0.0 5.4e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 RLN79197.1 - 3.1e-10 39.7 0.0 5.6e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA-synt_1 PF00133.22 RLN79198.1 - 3.4e-164 547.4 0.0 2.2e-161 538.2 0.0 2.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 RLN79198.1 - 1.4e-22 80.3 0.1 9.5e-22 77.6 0.0 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 RLN79198.1 - 1.3e-13 50.4 0.1 5.5e-07 28.7 0.0 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 RLN79198.1 - 2.4e-07 30.5 0.1 0.029 13.9 0.0 3.3 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 RLN79198.1 - 0.00096 18.6 0.0 0.57 9.5 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Val_tRNA-synt_C PF10458.9 RLN79198.1 - 0.0024 18.1 4.1 0.0024 18.1 4.1 2.2 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1b PF00579.25 RLN79198.1 - 0.1 11.9 0.1 0.37 10.1 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) tRNA-synt_1c PF00749.21 RLN79198.1 - 0.2 10.5 0.1 0.38 9.6 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain MGC-24 PF05283.11 RLN79201.1 - 0.55 10.7 9.3 1 9.8 9.3 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin NMD3 PF04981.13 RLN79202.1 - 6.1e-77 258.4 6.2 8.8e-77 257.8 6.2 1.2 1 0 0 1 1 1 1 NMD3 family DNA_RNApol_7kD PF03604.13 RLN79203.1 - 1.9e-14 53.1 6.9 2.4e-14 52.7 6.9 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit Nudix_N_2 PF14803.6 RLN79203.1 - 0.0038 17.1 0.3 0.49 10.4 0.0 2.2 2 0 0 2 2 2 2 Nudix N-terminal zf-Mss51 PF13824.6 RLN79203.1 - 0.031 14.4 1.3 0.27 11.4 0.1 2.2 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DZR PF12773.7 RLN79203.1 - 0.042 13.9 0.1 0.059 13.4 0.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_13 PF09855.9 RLN79203.1 - 0.056 13.6 0.3 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Zn_ribbon_SprT PF17283.2 RLN79203.1 - 0.063 13.2 1.8 0.092 12.7 1.8 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain FYDLN_acid PF09538.10 RLN79203.1 - 0.23 12.1 0.3 0.25 12.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Rubredoxin_2 PF18073.1 RLN79203.1 - 1 9.1 5.0 4.7 7.0 0.3 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain U3_assoc_6 PF08640.11 RLN79204.1 - 3.6e-25 87.9 2.1 1.3e-24 86.0 1.1 2.4 2 1 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 RLN79204.1 - 1.6e-05 25.3 11.4 0.36 11.8 0.0 7.4 7 1 1 8 8 8 2 Tetratricopeptide repeat NRDE-2 PF08424.10 RLN79204.1 - 2.6e-05 23.5 4.6 0.0001 21.6 0.1 3.0 3 1 0 3 3 3 1 NRDE-2, necessary for RNA interference FBD PF08387.10 RLN79204.1 - 0.054 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 FBD Suf PF05843.14 RLN79204.1 - 0.081 12.9 0.8 6.9 6.6 0.0 3.1 3 1 0 3 3 3 0 Suppressor of forked protein (Suf) Lipase_chap PF03280.14 RLN79204.1 - 0.5 10.3 4.8 0.75 9.7 0.1 3.2 2 1 1 3 3 3 0 Proteobacterial lipase chaperone protein TPR_16 PF13432.6 RLN79204.1 - 0.73 10.5 5.7 1.9 9.2 1.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2594 PF10769.9 RLN79204.1 - 0.94 9.6 3.4 2.8 8.0 0.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2594) Hus1 PF04005.12 RLN79205.1 - 2.3e-51 174.6 0.2 2.7e-51 174.4 0.2 1.1 1 0 0 1 1 1 1 Hus1-like protein RNase_T PF00929.24 RLN79206.1 - 3.6e-07 30.9 0.0 9e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Exonuclease RCS1 PF07326.11 RLN79206.1 - 0.00017 21.6 0.3 0.00035 20.6 0.3 1.5 1 0 0 1 1 1 1 Regulator of chromosome segregation 1 Aldedh PF00171.22 RLN79207.1 - 1.1e-37 129.7 0.0 2e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Sec23_trunk PF04811.15 RLN79227.1 - 2.1e-71 240.4 0.0 2.8e-71 239.9 0.0 1.1 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 RLN79227.1 - 3.9e-28 98.0 0.0 7.3e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 RLN79227.1 - 6e-22 77.4 0.4 1.8e-21 75.9 0.1 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 RLN79227.1 - 8.2e-14 51.3 0.3 1.8e-11 43.7 0.0 2.6 2 0 0 2 2 2 2 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 RLN79227.1 - 0.0008 19.4 2.7 0.0016 18.4 2.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger SAM_2 PF07647.17 RLN79246.1 - 3.9e-15 55.7 0.1 9.5e-15 54.5 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RLN79246.1 - 1.4e-14 54.3 0.1 2.7e-14 53.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IQ PF00612.27 RLN79246.1 - 6.5e-12 44.1 22.2 0.008 15.9 0.8 5.6 5 0 0 5 5 5 5 IQ calmodulin-binding motif Ank PF00023.30 RLN79246.1 - 1.1e-05 25.6 0.7 2.8e-05 24.4 0.7 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 RLN79246.1 - 7.2e-05 23.3 0.0 0.00028 21.4 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN79246.1 - 0.00021 21.5 0.1 0.00056 20.2 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 RLN79246.1 - 0.001 19.6 0.1 0.0049 17.4 0.1 2.2 2 0 0 2 2 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN79246.1 - 0.003 17.8 0.1 0.0072 16.6 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) FAM76 PF16046.5 RLN79246.1 - 0.56 9.5 5.6 0.96 8.7 5.6 1.3 1 0 0 1 1 1 0 FAM76 protein APG6_N PF17675.1 RLN79246.1 - 2.9 8.4 29.2 3.7 8.1 2.8 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Spc7 PF08317.11 RLN79246.1 - 7.3 5.4 17.4 13 4.6 17.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CPBP PF02517.16 RLN79247.1 - 5.6e-13 49.1 4.3 5.6e-13 49.1 4.3 2.6 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease adh_short PF00106.25 RLN79248.1 - 2.3e-32 112.1 0.2 4.2e-32 111.2 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN79248.1 - 3.9e-22 79.0 0.1 1.3e-21 77.3 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 RLN79248.1 - 0.00017 21.1 0.3 0.00028 20.4 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 RLN79248.1 - 0.011 14.8 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.10 RLN79248.1 - 0.011 15.6 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 RLN79248.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ORF_12_N PF18042.1 RLN79248.1 - 0.18 12.2 0.4 41 4.7 0.0 2.9 2 1 1 3 3 3 0 ORF 12 gene product N-terminal UPRTase PF14681.6 RLN79265.1 - 3.7e-23 82.1 0.1 1.3e-20 73.7 0.0 2.2 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase CENP-B_N PF04218.13 RLN79265.1 - 2.2e-06 27.2 0.2 4.2e-06 26.3 0.2 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 RLN79265.1 - 0.0043 16.8 0.2 0.012 15.4 0.2 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 RLN79265.1 - 0.0087 16.2 0.2 0.0087 16.2 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 RLN79265.1 - 0.037 14.0 0.1 0.072 13.1 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 RLN79265.1 - 0.087 12.7 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_7 PF02796.15 RLN79265.1 - 0.14 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Cpn60_TCP1 PF00118.24 RLN79266.1 - 1.5e-11 43.6 0.0 4.3e-11 42.1 0.0 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family LRR_9 PF14580.6 RLN79267.1 - 6.9e-14 51.7 0.0 2.1e-13 50.1 0.0 1.6 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 RLN79267.1 - 1.4e-08 34.3 6.2 2.3e-07 30.5 0.9 3.5 3 2 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 RLN79267.1 - 1.9e-08 34.4 0.4 0.00012 22.4 0.0 3.6 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN79267.1 - 0.008 16.6 0.7 1.6 9.6 0.0 3.6 4 0 0 4 4 4 1 Leucine Rich Repeat GDI PF00996.18 RLN79268.1 - 8.6e-42 143.1 0.0 2.1e-20 72.7 0.0 3.0 2 1 1 3 3 3 3 GDP dissociation inhibitor BT1 PF03092.16 RLN79280.1 - 1.9e-17 62.7 0.6 4.8e-14 51.5 0.8 2.0 2 0 0 2 2 2 2 BT1 family PUCC PF03209.15 RLN79280.1 - 0.0014 17.7 0.4 0.003 16.6 0.4 1.7 1 1 0 1 1 1 1 PUCC protein BT1 PF03092.16 RLN79281.1 - 2.9e-17 62.1 9.3 2.7e-11 42.4 0.5 3.3 3 0 0 3 3 3 3 BT1 family BT1 PF03092.16 RLN79282.1 - 4.5e-17 61.5 15.5 3.3e-12 45.4 1.0 3.2 3 0 0 3 3 3 3 BT1 family PUCC PF03209.15 RLN79282.1 - 0.0023 17.0 4.2 0.026 13.6 4.1 2.4 1 1 0 1 1 1 1 PUCC protein YajC PF02699.15 RLN79282.1 - 0.88 9.5 4.4 16 5.4 0.5 2.9 2 0 0 2 2 2 0 Preprotein translocase subunit DUF5083 PF16890.5 RLN79282.1 - 2.8 7.6 6.0 18 5.1 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5083) DUF3810 PF12725.7 RLN79282.1 - 3.4 6.9 8.4 7.2 5.9 1.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) BT1 PF03092.16 RLN79283.1 - 8.6e-35 119.9 41.3 3.6e-13 48.6 1.2 6.3 6 0 0 6 6 6 6 BT1 family PUCC PF03209.15 RLN79283.1 - 0.0062 15.6 22.9 0.011 14.7 0.1 5.0 4 1 0 4 4 4 2 PUCC protein Hid1 PF12722.7 RLN79306.1 - 8.1e-42 143.3 0.0 9.4e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 RLN79306.1 - 1.2e-29 103.2 0.0 1.5e-29 103.0 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Ku_PK_bind PF08785.11 RLN79306.1 - 0.048 13.8 0.3 0.4 10.8 0.0 2.1 1 1 1 2 2 2 0 Ku C terminal domain like IP_trans PF02121.18 RLN79307.1 - 4.2e-77 259.1 0.5 1.3e-76 257.5 0.5 1.6 1 1 0 1 1 1 1 Phosphatidylinositol transfer protein DUF2807 PF10988.8 RLN79343.1 - 6.6e-14 52.1 7.7 6.6e-10 39.1 1.6 2.3 1 1 1 2 2 2 2 Putative auto-transporter adhesin, head GIN domain AIM3 PF17096.5 RLN79344.1 - 0.22 12.5 2.0 0.56 11.2 2.0 1.7 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Myb_DNA-bind_6 PF13921.6 RLN79345.1 - 4.2e-25 87.8 0.8 4.5e-15 55.6 0.2 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 RLN79345.1 - 1e-24 86.4 11.5 3.3e-13 49.6 0.9 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 RLN79345.1 - 0.1 13.0 2.3 1.8 9.0 0.1 2.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 RLN79345.1 - 0.16 12.1 0.2 11 6.2 0.1 2.8 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Sugar_tr PF00083.24 RLN79359.1 - 1.5e-39 136.2 5.4 1.8e-39 135.9 5.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN79359.1 - 4e-15 55.6 12.6 5.1e-15 55.3 12.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_5 PF05631.14 RLN79359.1 - 2e-05 23.7 1.3 2.7e-05 23.3 1.3 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM TRI12 PF06609.13 RLN79359.1 - 0.0012 17.4 6.2 0.0016 17.0 6.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 RLN79359.1 - 0.0046 16.3 6.9 0.007 15.7 6.9 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TraT PF05818.12 RLN79380.1 - 0.11 12.2 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Gly-zipper_Omp PF13488.6 RLN79380.1 - 8.9 6.4 19.3 0.32 11.0 12.1 2.1 2 1 0 2 2 2 0 Glycine zipper V_ATPase_I PF01496.19 RLN79381.1 - 1.7e-60 204.9 8.8 1.9e-60 204.8 8.8 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family GFO_IDH_MocA PF01408.22 RLN79382.1 - 2.5e-14 54.1 0.0 3.9e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 RLN79382.1 - 3.2e-07 30.4 0.0 1.4e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 RLN79383.1 - 1.3e-29 103.4 0.9 9.5e-15 55.5 0.1 2.5 2 0 0 2 2 2 2 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 RLN79383.1 - 3e-10 40.1 0.0 0.00034 20.6 0.0 2.8 3 0 0 3 3 3 2 Oxidoreductase family, C-terminal alpha/beta domain PuR_N PF09182.10 RLN79383.1 - 0.029 14.3 0.3 1.4 8.9 0.0 3.3 4 0 0 4 4 4 0 Bacterial purine repressor, N-terminal CLP_protease PF00574.23 RLN79383.1 - 0.18 11.7 0.5 5.5 6.8 0.1 2.6 2 0 0 2 2 2 0 Clp protease Aconitase_C PF00694.19 RLN79384.1 - 5.4e-06 26.8 0.0 1.5e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 Aconitase C-terminal domain FAP PF07174.11 RLN79385.1 - 0.88 9.0 11.5 1.3 8.4 11.5 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) PCMT PF01135.19 RLN79386.1 - 2.6e-60 203.8 0.0 3.7e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 RLN79386.1 - 0.0004 20.4 0.0 0.00068 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN79386.1 - 0.0027 17.5 0.0 0.0056 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN79386.1 - 0.049 14.3 0.1 0.14 12.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 RLN79386.1 - 0.076 12.8 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Sulfate_transp PF00916.20 RLN79409.1 - 0.00022 20.1 7.0 0.00035 19.5 7.0 1.3 1 0 0 1 1 1 1 Sulfate permease family zf-C3HC4_5 PF17121.5 RLN79409.1 - 0.19 11.6 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PH PF00169.29 RLN79410.1 - 0.003 18.0 0.0 3.4 8.2 0.0 2.4 2 0 0 2 2 2 2 PH domain VPR PF00522.18 RLN79410.1 - 6.9 6.8 6.6 9.6 6.3 0.1 2.7 3 0 0 3 3 3 0 VPR/VPX protein Beach PF02138.18 RLN79412.1 - 2.4e-120 401.1 0.0 4.9e-120 400.1 0.0 1.5 2 0 0 2 2 2 1 Beige/BEACH domain Peptidase_M8 PF01457.16 RLN79412.1 - 7.8e-83 278.9 3.8 1.4e-82 278.1 3.8 1.3 1 0 0 1 1 1 1 Leishmanolysin EGF_2 PF07974.13 RLN79412.1 - 2.5e-08 34.2 141.5 0.0027 18.0 7.5 9.7 9 0 0 9 9 9 6 EGF-like domain Ank_2 PF12796.7 RLN79412.1 - 1.1e-06 29.2 0.0 4.2e-06 27.2 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN79412.1 - 4e-06 27.0 0.1 1.3e-05 25.3 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN79412.1 - 6.6e-05 23.4 0.0 0.094 13.3 0.0 4.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) WD40 PF00400.32 RLN79412.1 - 0.00015 22.5 0.9 0.069 14.0 0.1 3.7 2 0 0 2 2 2 1 WD domain, G-beta repeat Ank PF00023.30 RLN79412.1 - 0.00025 21.4 1.3 0.0032 17.9 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat PH_BEACH PF14844.6 RLN79412.1 - 0.00038 20.5 0.0 0.0012 18.9 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 RLN79412.1 - 0.0062 16.7 5.5 0.017 15.2 0.0 3.4 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily Ank_3 PF13606.6 RLN79412.1 - 0.0095 16.4 0.1 0.12 13.0 0.0 3.1 3 0 0 3 3 1 1 Ankyrin repeat DUF3741 PF12552.8 RLN79412.1 - 0.026 14.5 0.0 0.083 12.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) Ank_5 PF13857.6 RLN79413.1 - 5.3e-18 64.8 1.3 2.4e-10 40.5 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN79413.1 - 1.4e-14 54.2 0.2 2.4e-07 31.2 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN79413.1 - 8.2e-14 52.0 0.2 6.5e-07 29.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RLN79413.1 - 1.3e-10 41.2 1.3 0.0011 19.3 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 RLN79413.1 - 1.3e-09 37.5 0.1 0.00095 19.4 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Macoilin PF09726.9 RLN79413.1 - 0.095 11.2 21.3 0.17 10.4 21.3 1.3 1 0 0 1 1 1 0 Macoilin family Nop14 PF04147.12 RLN79413.1 - 0.12 10.6 19.0 0.16 10.2 19.0 1.1 1 0 0 1 1 1 0 Nop14-like family zf-C3HC4_4 PF15227.6 RLN79413.1 - 1 9.6 6.9 0.88 9.8 3.9 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Cytochrom_c3_2 PF14537.6 RLN79413.1 - 2.9 8.4 15.6 0.047 14.1 1.4 2.7 2 0 0 2 2 2 0 Cytochrome c3 PA26 PF04636.13 RLN79413.1 - 3.2 6.6 7.1 6.3 5.6 7.1 1.5 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Spt20 PF12090.8 RLN79413.1 - 3.2 7.3 13.3 6.8 6.2 13.3 1.5 1 0 0 1 1 1 0 Spt20 family NARP1 PF12569.8 RLN79413.1 - 3.6 6.4 14.5 5.5 5.8 14.5 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ECR1_N PF14382.6 RLN79430.1 - 2e-13 49.9 0.5 4e-13 48.9 0.5 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 RLN79430.1 - 1.3e-10 41.4 0.1 3e-10 40.3 0.1 1.7 1 0 0 1 1 1 1 KH domain PHF12_MRG_bd PF16737.5 RLN79430.1 - 0.029 14.1 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 PHD finger protein 12 MRG binding domain MARVEL PF01284.23 RLN79432.1 - 5e-09 36.3 15.1 7.2e-09 35.8 15.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.12 RLN79432.1 - 7.1e-05 22.6 12.6 0.00024 20.9 12.5 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF588) DUF4118 PF13493.6 RLN79432.1 - 2.4 8.0 11.3 0.24 11.2 1.9 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4118) Thioredoxin PF00085.20 RLN79433.1 - 5.7e-44 148.3 0.9 2.5e-23 82.0 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.6 RLN79433.1 - 4.8e-09 36.4 0.1 0.0016 18.7 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 RLN79433.1 - 2.1e-08 34.6 1.8 0.09 13.2 0.1 4.3 2 2 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 RLN79433.1 - 7.6e-08 32.4 0.5 0.0014 18.8 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 RLN79433.1 - 1.1e-07 31.5 0.3 2.7e-05 23.7 0.0 2.3 2 1 0 2 2 2 2 OST3 / OST6 family, transporter family Nucleocap_ssRNA PF11128.8 RLN79433.1 - 0.00011 22.0 0.0 0.27 10.9 0.0 2.4 2 0 0 2 2 2 2 Plant viral coat protein nucleocapsid Thioredoxin_9 PF14595.6 RLN79433.1 - 0.00014 21.7 0.1 0.028 14.2 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 RLN79433.1 - 0.00014 21.8 1.0 0.036 14.0 0.1 2.6 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 RLN79433.1 - 0.00023 20.9 0.6 0.66 9.7 0.1 2.5 2 0 0 2 2 2 2 Redoxin Phosducin PF02114.16 RLN79433.1 - 0.00035 19.6 0.1 0.039 12.9 0.0 2.5 3 0 0 3 3 3 1 Phosducin Nse4_C PF08743.10 RLN79433.1 - 0.13 12.5 0.7 0.25 11.6 0.3 1.6 2 0 0 2 2 2 0 Nse4 C-terminal PP28 PF10252.9 RLN79434.1 - 3.9e-22 78.5 20.7 3.9e-22 78.5 20.7 3.0 4 1 0 4 4 4 1 Casein kinase substrate phosphoprotein PP28 SAP PF02037.27 RLN79434.1 - 1.1e-08 34.7 1.4 2.4e-08 33.5 1.4 1.7 1 0 0 1 1 1 1 SAP domain Cwf_Cwc_15 PF04889.12 RLN79434.1 - 0.75 9.5 35.6 0.17 11.6 4.8 2.6 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Thioredoxin PF00085.20 RLN79435.1 - 3.3e-08 33.5 0.0 5.5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 RLN79435.1 - 0.00053 19.0 0.1 0.00077 18.5 0.1 1.3 1 0 0 1 1 1 1 Phosducin DUF3619 PF12279.8 RLN79435.1 - 0.07 13.4 2.5 0.26 11.6 2.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3619) DUF3037 PF11236.8 RLN79435.1 - 0.12 12.8 1.2 0.27 11.7 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) DUF2570 PF10828.8 RLN79435.1 - 0.3 10.9 5.0 0.26 11.1 3.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) OmpH PF03938.14 RLN79435.1 - 0.4 11.0 9.7 0.19 12.0 6.9 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ras PF00071.22 RLN79436.1 - 1.6e-48 164.4 0.8 2.9e-48 163.5 0.8 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN79436.1 - 6.2e-22 78.1 0.1 6.2e-22 78.1 0.1 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN79436.1 - 2.7e-10 40.0 0.1 6.5e-10 38.7 0.1 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RLN79436.1 - 0.0048 16.5 0.1 0.0048 16.5 0.1 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PX PF00787.24 RLN79437.1 - 0.0041 17.1 0.1 0.012 15.6 0.1 1.8 1 1 0 1 1 1 1 PX domain Adeno_E3A PF05248.12 RLN79437.1 - 0.011 15.8 1.3 0.015 15.3 0.8 1.5 2 0 0 2 2 2 0 Adenovirus E3A Glycos_transf_1 PF00534.20 RLN79438.1 - 0.0001 21.9 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RLN79438.1 - 0.009 16.5 0.0 0.021 15.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 TPR_2 PF07719.17 RLN79457.1 - 5.9e-26 88.4 0.0 0.12 12.6 0.0 10.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 RLN79457.1 - 4.9e-25 87.9 1.7 6.3e-09 36.3 0.0 6.7 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 RLN79457.1 - 1e-19 70.8 0.0 0.00016 22.1 0.0 5.8 2 1 3 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 RLN79457.1 - 6.3e-19 67.4 0.0 0.0011 18.6 0.0 6.7 7 0 0 7 7 7 3 TPR repeat TPR_14 PF13428.6 RLN79457.1 - 1.8e-18 65.6 4.2 0.042 14.7 0.0 10.1 4 1 6 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN79457.1 - 6.7e-18 63.3 0.0 0.028 14.6 0.0 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN79457.1 - 1.3e-16 59.6 0.0 0.06 13.2 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 RLN79457.1 - 8.3e-15 54.9 10.8 0.003 17.8 0.0 7.0 2 1 4 7 7 7 5 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN79457.1 - 1.8e-12 47.3 2.3 0.0038 17.4 0.0 5.5 4 1 2 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 RLN79457.1 - 2.1e-10 40.2 0.0 0.4 11.2 0.0 7.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN79457.1 - 5.7e-09 35.4 0.4 2.5 8.3 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN79457.1 - 6.8e-09 35.8 4.8 0.0031 17.6 0.0 5.4 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 RLN79457.1 - 8.8e-08 32.3 0.1 8.3 7.3 0.0 7.8 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN79457.1 - 0.00014 21.6 2.2 4.7 7.2 0.0 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat Rhodanese PF00581.20 RLN79457.1 - 0.0002 21.8 0.0 0.00061 20.3 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain NARP1 PF12569.8 RLN79457.1 - 0.00022 20.3 4.6 0.0013 17.8 0.0 3.6 3 1 0 4 4 4 1 NMDA receptor-regulated protein 1 DUF3808 PF10300.9 RLN79457.1 - 0.00083 18.2 0.1 0.43 9.3 0.0 3.4 1 1 1 3 3 3 1 Protein of unknown function (DUF3808) HrpB1_HrpK PF09613.10 RLN79457.1 - 0.0012 18.5 0.0 1.6 8.4 0.0 2.8 1 1 1 2 2 2 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_20 PF14561.6 RLN79457.1 - 0.0016 18.7 12.4 0.27 11.6 0.0 6.0 5 1 1 6 6 5 1 Tetratricopeptide repeat DUF4810 PF16068.5 RLN79457.1 - 0.01 16.3 2.8 0.023 15.2 0.1 3.1 2 1 0 2 2 1 0 Domain of unknown function (DUF4810) Sec16_C PF12931.7 RLN79457.1 - 0.032 13.9 0.1 0.068 12.8 0.1 1.5 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 TPR_4 PF07721.14 RLN79457.1 - 0.042 14.5 0.3 0.042 14.5 0.3 5.8 5 0 0 5 5 4 0 Tetratricopeptide repeat Tryp_alpha_amyl PF00234.22 RLN79457.1 - 0.047 14.1 3.4 0.081 13.4 0.8 2.6 3 0 0 3 3 2 0 Protease inhibitor/seed storage/LTP family DUF2514 PF10721.9 RLN79457.1 - 4.1 7.4 8.2 0.37 10.8 1.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2514) Sybindin PF04099.12 RLN79458.1 - 4.2e-29 101.3 0.0 5.2e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 RLN79458.1 - 0.0002 21.5 0.0 0.00032 20.8 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region PH PF00169.29 RLN79459.1 - 7.7e-07 29.6 0.0 1.6e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN79459.1 - 0.028 14.7 0.0 0.059 13.7 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Ank_2 PF12796.7 RLN79480.1 - 1.5e-23 83.1 6.3 3.2e-07 30.8 0.2 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN79480.1 - 9.6e-20 70.7 19.1 1e-06 29.2 0.1 5.3 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN79480.1 - 3.4e-14 51.5 0.5 0.69 10.7 0.0 7.1 6 1 1 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 RLN79480.1 - 7.7e-14 51.6 7.3 0.0092 16.3 0.0 7.0 1 1 6 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 RLN79480.1 - 2.4e-05 24.6 3.1 3.3 8.3 0.1 5.5 3 1 1 4 4 4 1 Ankyrin repeat Phage_holin_3_6 PF07332.11 RLN79481.1 - 0.44 10.6 2.6 0.89 9.6 2.6 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Dioxygenase_C PF00775.21 RLN79482.1 - 3.9e-07 29.7 0.3 8.5e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 Dioxygenase Pkinase_Tyr PF07714.17 RLN79483.1 - 4.6e-73 245.7 0.0 1.9e-36 125.7 0.0 4.7 3 2 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 RLN79483.1 - 2.8e-55 187.5 0.0 1.7e-29 103.0 0.0 5.5 4 2 0 4 4 4 3 Protein kinase domain Kinase-like PF14531.6 RLN79483.1 - 0.0018 17.7 0.0 0.038 13.3 0.0 2.7 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 RLN79483.1 - 0.0019 18.2 0.0 0.0019 18.2 0.0 5.7 6 1 0 6 6 6 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN79483.1 - 0.022 14.1 0.2 0.7 9.2 0.0 2.9 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2895 PF11444.8 RLN79483.1 - 0.12 11.7 0.2 0.45 9.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2895) Hemerythrin PF01814.23 RLN79483.1 - 2 9.0 14.6 7.8 7.1 2.0 4.8 4 0 0 4 4 4 0 Hemerythrin HHE cation binding domain GyrI-like PF06445.15 RLN79484.1 - 1.6e-14 54.5 0.0 1.8e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.6 RLN79484.1 - 1.3e-11 44.8 0.0 1.4e-11 44.7 0.0 1.0 1 0 0 1 1 1 1 Integron-associated effector binding protein PP2C PF00481.21 RLN79485.1 - 2.6e-63 214.1 0.0 3.7e-63 213.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C FHA PF00498.26 RLN79485.1 - 2.6e-16 59.7 0.0 1.7e-12 47.5 0.0 2.6 2 0 0 2 2 2 2 FHA domain PP2C_2 PF13672.6 RLN79485.1 - 9.2e-07 28.7 0.0 3.1e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C Yop-YscD_cpl PF16697.5 RLN79485.1 - 0.00011 22.5 0.0 0.00032 21.0 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain CENP-B_dimeris PF09026.10 RLN79485.1 - 0.031 14.7 0.3 0.074 13.5 0.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4663 PF15668.5 RLN79485.1 - 0.055 12.5 1.8 0.088 11.9 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) TFIIE-A_C PF11521.8 RLN79485.1 - 0.14 12.5 2.5 12 6.3 1.0 2.5 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Steroid_dh PF02544.16 RLN79487.1 - 1.7e-29 102.8 0.2 2.6e-29 102.1 0.2 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase GyrI-like PF06445.15 RLN79487.1 - 2.8e-17 63.4 0.0 4.7e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.6 RLN79487.1 - 1.4e-10 41.6 0.0 1.9e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Integron-associated effector binding protein Ubiquitin_2 PF14560.6 RLN79487.1 - 0.00013 22.3 0.0 0.00042 20.7 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-like domain DUF1295 PF06966.12 RLN79487.1 - 0.00088 18.9 0.7 0.0032 17.0 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 RLN79487.1 - 0.13 12.6 0.3 0.13 12.6 0.3 2.3 2 1 1 3 3 3 0 Phospholipid methyltransferase Ribosomal_L1 PF00687.21 RLN79488.1 - 3.7e-46 157.4 0.2 3.7e-46 157.4 0.2 2.4 2 1 0 2 2 2 1 Ribosomal protein L1p/L10e family Rsc14 PF08586.10 RLN79488.1 - 0.065 14.0 0.7 0.065 14.0 0.7 3.3 1 1 2 3 3 3 0 RSC complex, Rsc14/Ldb7 subunit DUF1970 PF09301.10 RLN79488.1 - 0.072 13.4 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) AF-4 PF05110.13 RLN79488.1 - 0.5 8.4 38.3 0.61 8.1 38.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GREB1 PF15782.5 RLN79488.1 - 2.9 4.9 17.5 3.6 4.6 17.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Borrelia_P83 PF05262.11 RLN79488.1 - 5 5.5 33.4 7.2 5.0 33.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Adaptin_N PF01602.20 RLN79489.1 - 8e-44 150.1 0.0 9e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 RLN79489.1 - 0.00011 22.3 0.1 0.00026 21.1 0.0 1.6 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Anp1 PF03452.14 RLN79525.1 - 1.7e-41 142.4 0.4 5.8e-41 140.7 0.4 1.7 1 1 0 1 1 1 1 Anp1 zf-SNAP50_C PF12251.8 RLN79545.1 - 0.047 13.4 1.7 0.086 12.5 1.7 1.4 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal FYVE PF01363.21 RLN79545.1 - 0.071 13.3 8.4 0.14 12.3 8.4 1.5 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN79545.1 - 0.2 11.9 4.8 0.4 10.9 4.8 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_5 PF14634.6 RLN79545.1 - 1.4 9.0 10.6 9.9 6.2 10.9 2.2 1 1 1 2 2 2 0 zinc-RING finger domain IRK_C PF17655.1 RLN79546.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Inward rectifier potassium channel C-terminal domain DPBB_1 PF03330.18 RLN79547.1 - 3.7e-09 36.7 0.2 6.7e-09 35.9 0.2 1.4 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 RLN79547.1 - 0.00029 20.7 2.9 0.00048 19.9 2.9 1.5 1 1 0 1 1 1 1 Barwin family zf-DNA_Pol PF08996.10 RLN79547.1 - 0.27 11.0 4.2 0.4 10.4 4.2 1.2 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger p450 PF00067.22 RLN79551.1 - 1.2e-69 235.2 0.0 1.6e-69 234.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Myotub-related PF06602.14 RLN79552.1 - 3.3e-146 486.7 0.1 5.5e-146 486.0 0.1 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.21 RLN79552.1 - 1e-17 64.0 9.6 4e-17 62.1 9.6 2.1 1 0 0 1 1 1 1 FYVE zinc finger NAD_binding_6 PF08030.12 RLN79552.1 - 6.8e-14 52.3 0.0 1.4e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 RLN79552.1 - 3.5e-13 49.6 0.0 8e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Y_phosphatase PF00102.27 RLN79552.1 - 1e-05 25.2 0.1 1.9e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 RLN79552.1 - 1.2e-05 25.1 0.1 2.5e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Ferric_reduct PF01794.19 RLN79552.1 - 0.00013 22.1 5.4 0.00029 21.0 5.4 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Y_phosphatase3 PF13350.6 RLN79552.1 - 0.00095 19.2 0.1 0.0044 17.0 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family 3-PAP PF12578.8 RLN79552.1 - 0.0067 16.2 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Myotubularin-associated protein GRAM PF02893.20 RLN79552.1 - 0.0095 15.8 0.1 0.047 13.6 0.1 2.1 1 1 0 1 1 1 1 GRAM domain Orthoreo_P10 PF07204.11 RLN79552.1 - 3.2 7.8 7.4 0.19 11.7 0.1 2.8 3 1 1 4 4 3 0 Orthoreovirus membrane fusion protein p10 p450 PF00067.22 RLN79553.1 - 4.5e-80 269.6 0.1 5.8e-80 269.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_6 PF00970.24 RLN79554.1 - 9.4e-35 118.9 0.0 1.6e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 RLN79554.1 - 2.5e-24 86.0 0.0 3.6e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_9 PF08021.11 RLN79554.1 - 0.00094 19.4 0.0 0.0015 18.7 0.0 1.3 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain NAD_binding_6 PF08030.12 RLN79554.1 - 0.0042 17.2 0.0 0.006 16.7 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF5044 PF16447.5 RLN79554.1 - 0.072 12.9 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5044) Complex1_LYR PF05347.15 RLN79555.1 - 4.2e-07 29.9 0.0 7e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF832 PF05734.11 RLN79555.1 - 0.099 12.1 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) Glyco_transf_20 PF00982.21 RLN79556.1 - 3.8e-179 596.3 0.0 4.9e-179 595.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 RLN79556.1 - 2e-36 125.3 0.0 3.4e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_hydro_3_C PF01915.22 RLN79556.1 - 0.15 12.0 0.0 2.7 7.9 0.0 2.4 2 1 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain Nop14 PF04147.12 RLN79556.1 - 1.6 6.9 9.5 2.2 6.4 9.5 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 RLN79556.1 - 1.9 8.6 9.5 3.1 7.9 9.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 RLN79556.1 - 2.3 7.5 8.5 3.5 7.0 8.5 1.2 1 0 0 1 1 1 0 SDA1 TFIIA PF03153.13 RLN79556.1 - 8.2 6.3 9.1 14 5.5 9.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 RLN79577.1 - 0.32 10.6 8.7 0.46 10.0 8.7 1.3 1 0 0 1 1 1 0 Spt20 family Ank_2 PF12796.7 RLN79578.1 - 4.7e-35 120.0 3.1 3e-08 34.2 0.0 6.9 2 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN79578.1 - 9.7e-29 99.4 12.8 0.00017 22.1 0.0 10.5 6 4 5 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN79578.1 - 1.8e-27 95.0 19.7 0.014 15.7 0.0 12.3 5 2 7 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN79578.1 - 1.1e-18 65.3 6.0 2.7 8.8 0.0 13.8 13 2 2 15 15 15 3 Ankyrin repeat Ank PF00023.30 RLN79578.1 - 0.00093 19.5 3.5 33 5.2 0.0 7.3 5 3 3 8 8 8 0 Ankyrin repeat DUF5049 PF16468.5 RLN79578.1 - 0.0064 16.4 0.0 42 4.1 0.0 5.1 5 1 1 6 6 6 0 Domain of unknown function (DUF5049) PH PF00169.29 RLN79579.1 - 2e-19 70.1 1.2 6e-09 36.4 0.1 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 RLN79579.1 - 7.4e-05 23.1 9.4 0.00034 21.0 0.1 3.7 3 1 0 3 3 3 1 Pleckstrin homology domain PH_8 PF15409.6 RLN79579.1 - 0.0092 16.2 1.5 7.9 6.8 0.0 3.1 3 1 0 3 3 3 2 Pleckstrin homology domain Chalcone PF02431.15 RLN79579.1 - 0.026 14.0 0.0 9.2 5.6 0.0 2.5 2 0 0 2 2 2 0 Chalcone-flavanone isomerase RNA_pol_3_Rpc31 PF11705.8 RLN79579.1 - 0.18 12.0 15.1 0.039 14.2 7.0 2.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2457 PF10446.9 RLN79579.1 - 0.23 10.6 31.9 0.0078 15.4 25.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DUF2722 PF10846.8 RLN79579.1 - 0.95 8.3 9.2 2 7.3 9.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CDC45 PF02724.14 RLN79579.1 - 2.2 6.4 21.4 5.7 5.1 21.4 1.6 1 0 0 1 1 1 0 CDC45-like protein SGT1 PF07093.11 RLN79579.1 - 4.2 5.7 9.7 7.7 4.8 9.7 1.3 1 0 0 1 1 1 0 SGT1 protein Apt1 PF10351.9 RLN79579.1 - 6.5 5.5 10.4 0.86 8.4 3.5 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Sigma70_ner PF04546.13 RLN79579.1 - 9.5 6.0 16.2 6.6 6.6 11.1 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region FlaC_arch PF05377.11 RLN79580.1 - 0.01 16.2 0.1 0.017 15.5 0.1 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Aldedh PF00171.22 RLN79581.1 - 1.4e-77 261.2 0.0 1.7e-77 260.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family COPI_assoc PF08507.10 RLN79582.1 - 1.4e-09 38.1 3.3 1.6e-09 37.9 3.3 1.0 1 0 0 1 1 1 1 COPI associated protein DUF202 PF02656.15 RLN79582.1 - 1.3 9.5 5.0 1.2 9.6 0.7 2.0 1 1 2 3 3 3 0 Domain of unknown function (DUF202) NTP_transf_2 PF01909.23 RLN79583.1 - 2e-10 40.8 0.0 4.2e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 RLN79583.1 - 3e-07 30.5 0.0 8.3e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 RLN79583.1 - 0.0091 16.1 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DNA_pol_B_palm PF14792.6 RLN79583.1 - 0.012 15.8 0.0 0.039 14.1 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase beta palm HA PF03457.14 RLN79584.1 - 2.5e-20 72.6 0.2 1.1e-06 28.9 0.0 3.2 3 0 0 3 3 3 3 Helicase associated domain COesterase PF00135.28 RLN79585.1 - 7.8e-58 196.6 1.4 2.2e-57 195.1 1.4 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RLN79585.1 - 0.037 13.9 0.2 0.16 11.8 0.1 2.1 2 1 0 2 2 2 0 alpha/beta hydrolase fold LCM PF04072.14 RLN79586.1 - 2.3e-18 66.8 0.0 4.1e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Acetyltransf_1 PF00583.25 RLN79586.1 - 2e-14 53.9 0.0 4.2e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RLN79586.1 - 9.3e-12 45.2 0.0 1.9e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RLN79586.1 - 7.7e-10 38.8 0.0 1.4e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN79586.1 - 0.00066 19.6 0.1 0.0033 17.4 0.1 2.1 2 1 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 RLN79586.1 - 0.066 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NIF PF03031.18 RLN79587.1 - 5e-54 182.3 0.0 7e-54 181.8 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 RLN79587.1 - 0.021 15.2 0.1 0.14 12.5 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase LRR_8 PF13855.6 RLN79589.1 - 7e-29 99.4 9.4 3.5e-12 45.9 0.1 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 RLN79589.1 - 6.7e-19 67.7 0.2 9.8e-06 25.8 0.1 3.9 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN79589.1 - 5.3e-08 32.3 4.6 2.3 9.1 0.2 6.3 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.6 RLN79589.1 - 2.2e-07 30.5 2.9 0.0093 15.5 0.2 2.3 1 1 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 RLN79589.1 - 4.6e-05 23.2 6.3 0.43 10.7 0.1 5.7 7 0 0 7 7 7 2 Leucine Rich repeat Pkinase PF00069.25 RLN79590.1 - 1.3e-51 175.6 0.0 2e-51 174.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN79590.1 - 1.7e-46 158.6 0.0 2.3e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PAP_PilO PF06864.12 RLN79590.1 - 0.012 14.4 0.2 0.023 13.6 0.2 1.3 1 0 0 1 1 1 0 Pilin accessory protein (PilO) APH PF01636.23 RLN79590.1 - 0.035 14.0 0.2 0.16 11.9 0.2 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family PAN_4 PF14295.6 RLN79591.1 - 5.2e-36 122.3 38.9 7.6e-10 38.5 1.9 4.5 5 0 0 5 5 5 4 PAN domain PAN_1 PF00024.26 RLN79591.1 - 1.1e-23 82.9 15.8 2.2e-06 27.5 0.9 4.1 3 1 1 4 4 4 4 PAN domain PAN_2 PF08276.11 RLN79591.1 - 0.42 10.8 38.8 0.081 13.1 3.4 4.2 4 0 0 4 4 4 0 PAN-like domain RAWUL PF16207.5 RLN79592.1 - 2.1e-09 37.9 0.1 2.8e-09 37.5 0.1 1.1 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like DUF3337 PF11816.8 RLN79592.1 - 3.4e-06 27.0 0.0 4.2e-06 26.7 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3337) SSF PF00474.17 RLN79614.1 - 5.6e-24 84.7 20.0 1.4e-22 80.2 9.1 2.2 2 1 0 2 2 2 2 Sodium:solute symporter family AAA_9 PF12781.7 RLN79615.1 - 2.1e-88 295.1 2.5 5.2e-88 293.8 2.5 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region MT PF12777.7 RLN79615.1 - 1e-55 189.2 7.3 1.8e-55 188.3 7.3 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.7 RLN79615.1 - 6e-16 58.5 0.0 1e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Spc7 PF08317.11 RLN79615.1 - 0.00023 20.1 6.4 0.00023 20.1 6.4 3.4 3 0 0 3 3 3 2 Spc7 kinetochore protein ATG16 PF08614.11 RLN79615.1 - 0.0016 18.7 0.2 0.0016 18.7 0.2 3.5 3 1 1 4 4 4 1 Autophagy protein 16 (ATG16) Viral_DNA_Zn_bi PF03728.13 RLN79615.1 - 0.026 15.1 0.1 0.12 12.9 0.0 2.2 2 0 0 2 2 2 0 Viral DNA-binding protein, zinc binding domain GAF PF01590.26 RLN79634.1 - 0.0014 19.3 1.7 0.0029 18.3 0.2 2.2 2 1 0 2 2 2 1 GAF domain FYVE PF01363.21 RLN79634.1 - 0.0018 18.4 6.9 0.0056 16.8 6.9 1.9 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN79634.1 - 0.68 10.2 4.7 7.8 6.7 1.5 3.0 2 0 0 2 2 2 0 FYVE-type zinc finger Glyco_hydro_31 PF01055.26 RLN79635.1 - 1.9e-20 73.5 0.0 2.2e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF2093 PF09866.9 RLN79635.1 - 0.092 12.2 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) NAT PF04768.13 RLN79635.1 - 0.096 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase FYVE PF01363.21 RLN79636.1 - 2.2e-05 24.5 13.1 4.8e-05 23.4 13.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN79636.1 - 0.055 13.7 6.4 0.13 12.4 6.4 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger WD40 PF00400.32 RLN79639.1 - 0.00089 20.0 0.0 0.089 13.7 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN79639.1 - 0.15 12.4 0.0 1.2 9.5 0.0 2.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4_3 PF13920.6 RLN79640.1 - 4.3e-11 42.5 10.3 4.3e-11 42.5 10.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN79640.1 - 1e-05 25.3 10.4 2.8e-05 23.9 10.4 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN79640.1 - 0.32 11.0 11.0 0.66 10.0 11.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 RLN79640.1 - 3.4 8.1 17.3 0.24 11.8 12.1 1.9 2 1 0 2 2 2 0 Ring finger domain SPX PF03105.19 RLN79640.1 - 4.5 7.1 21.8 0.16 11.8 15.6 1.6 2 0 0 2 2 2 0 SPX domain Menin PF05053.13 RLN79640.1 - 5.7 5.2 11.9 7.6 4.8 11.9 1.2 1 0 0 1 1 1 0 Menin Mito_carr PF00153.27 RLN79665.1 - 2.8e-37 126.5 2.2 3.2e-18 65.4 0.2 2.3 2 1 0 2 2 2 2 Mitochondrial carrier protein Serine_protease PF18405.1 RLN79665.1 - 2.3 7.3 5.2 1.3 8.1 0.3 2.1 1 1 1 2 2 2 0 Gammaproteobacterial serine protease SNAP PF14938.6 RLN79666.1 - 2.6e-15 56.6 6.9 3.8e-15 56.1 6.9 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP CBFB_NFYA PF02045.15 RLN79668.1 - 5.7e-27 94.1 8.1 5.7e-27 94.1 8.1 1.9 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DivIC PF04977.15 RLN79668.1 - 0.022 14.5 3.9 0.13 12.0 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator IreB PF06135.12 RLN79668.1 - 0.049 13.8 0.1 0.075 13.2 0.1 1.3 1 0 0 1 1 1 0 IreB regulatory phosphoprotein TPR_1 PF00515.28 RLN79669.1 - 6.6e-51 168.2 18.5 0.0095 15.7 0.2 21.9 22 0 0 22 22 22 12 Tetratricopeptide repeat TPR_2 PF07719.17 RLN79669.1 - 2e-45 149.3 48.5 0.0042 17.1 0.0 21.0 22 0 0 22 22 21 13 Tetratricopeptide repeat TPR_11 PF13414.6 RLN79669.1 - 4e-37 125.6 7.5 0.00035 20.2 0.1 15.3 11 5 5 16 16 16 8 TPR repeat TPR_17 PF13431.6 RLN79669.1 - 2.2e-28 96.6 21.7 0.0037 17.5 0.1 17.9 18 0 0 18 18 18 4 Tetratricopeptide repeat TPR_16 PF13432.6 RLN79669.1 - 3.4e-26 91.6 73.0 0.0001 22.9 2.9 15.7 10 6 6 16 16 16 9 Tetratricopeptide repeat TPR_9 PF13371.6 RLN79669.1 - 4e-26 90.9 76.7 5.8e-05 23.1 3.7 15.9 9 5 5 15 15 14 11 Tetratricopeptide repeat TPR_14 PF13428.6 RLN79669.1 - 1e-23 81.9 53.1 0.00062 20.4 0.9 16.0 12 5 5 17 17 16 6 Tetratricopeptide repeat TPR_19 PF14559.6 RLN79669.1 - 1e-22 80.4 38.1 0.00074 20.0 0.1 11.9 9 4 4 14 14 14 6 Tetratricopeptide repeat TPR_8 PF13181.6 RLN79669.1 - 1.9e-22 77.6 12.5 0.25 11.7 0.0 16.4 18 2 1 19 19 17 4 Tetratricopeptide repeat TPR_12 PF13424.6 RLN79669.1 - 2.8e-13 50.0 57.1 0.0081 16.4 0.6 13.4 11 4 4 15 15 14 6 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN79669.1 - 1.6e-05 25.0 24.0 0.14 12.4 0.2 7.7 6 2 1 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 RLN79669.1 - 4.9e-05 22.7 15.9 0.11 11.7 0.1 6.4 6 2 0 6 6 6 3 Tetratricopeptide repeat NARP1 PF12569.8 RLN79669.1 - 0.00011 21.3 1.4 6.6 5.5 0.0 5.4 6 1 0 6 6 6 2 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 RLN79669.1 - 0.00081 19.3 45.8 3.5 7.9 0.1 13.7 17 1 0 17 17 16 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN79669.1 - 0.0039 17.2 3.6 0.6 10.2 0.1 4.2 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 RLN79669.1 - 0.025 14.9 11.6 4.4 7.7 0.4 6.2 6 1 1 7 7 7 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 RLN79669.1 - 0.042 13.3 15.1 0.076 12.5 0.0 6.4 7 0 0 7 7 7 0 SHNi-TPR TPR_6 PF13174.6 RLN79669.1 - 0.094 13.4 0.1 0.094 13.4 0.1 12.2 16 0 0 16 16 13 0 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 RLN79669.1 - 0.14 11.6 0.2 1.6 8.2 0.0 2.7 3 0 0 3 3 3 0 Est1 DNA/RNA binding domain Aldedh PF00171.22 RLN79670.1 - 5.6e-103 344.9 5.9 1.7e-86 290.6 0.1 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family P22_AR_C PF10548.9 RLN79671.1 - 0.058 13.6 0.1 0.47 10.7 0.0 2.0 2 0 0 2 2 2 0 P22AR C-terminal domain Dimer_Tnp_hAT PF05699.14 RLN79672.1 - 1.6e-08 34.2 0.0 2.6e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF1564 PF07600.11 RLN79673.1 - 0.084 12.6 0.3 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) LPD28 PF18843.1 RLN79673.1 - 0.09 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 28 Pkinase_Tyr PF07714.17 RLN79693.1 - 2.1e-13 50.2 0.0 1.5e-12 47.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN79693.1 - 0.049 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNase_PH PF01138.21 RLN79694.1 - 6e-23 81.8 0.1 9.3e-23 81.2 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RLN79694.1 - 1.6e-10 40.8 0.0 4.7e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 STIMATE PF12400.8 RLN79695.1 - 1.3e-34 119.5 2.4 2.3e-34 118.6 2.4 1.4 1 0 0 1 1 1 1 STIMATE family DNA_topoisoIV PF00521.20 RLN79696.1 - 3.7e-130 434.7 0.0 5.3e-130 434.1 0.0 1.2 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 RLN79696.1 - 3.9e-46 156.5 0.5 3.2e-41 140.6 0.3 4.2 4 0 0 4 4 4 2 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 RLN79696.1 - 4e-24 85.0 0.6 9.6e-24 83.8 0.6 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 RLN79696.1 - 4.7e-12 46.4 0.0 1.9e-11 44.5 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EF-hand_6 PF13405.6 RLN79696.1 - 2.3e-11 42.7 5.8 0.011 15.6 0.1 4.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 RLN79696.1 - 4.4e-10 38.4 8.7 0.0073 15.8 0.1 5.3 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 RLN79696.1 - 1.5e-07 31.7 8.2 0.0048 17.3 0.1 4.4 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN79696.1 - 5.6e-06 25.6 6.5 0.22 11.1 0.2 4.3 4 0 0 4 4 4 3 EF hand Toprim PF01751.22 RLN79696.1 - 2.1e-05 24.7 0.0 7.6e-05 22.9 0.0 2.0 1 0 0 1 1 1 1 Toprim domain EF-hand_8 PF13833.6 RLN79696.1 - 0.007 16.2 5.8 0.33 10.8 0.1 4.4 4 0 0 4 4 4 1 EF-hand domain pair K-box PF01486.17 RLN79696.1 - 0.062 13.5 0.6 0.22 11.7 0.6 1.9 1 0 0 1 1 1 0 K-box region VWA PF00092.28 RLN79697.1 - 5.1e-10 39.9 0.0 1.1e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RLN79697.1 - 1.4e-07 32.1 0.0 5.6e-07 30.2 0.0 2.2 1 0 0 1 1 1 1 von Willebrand factor type A domain YabA PF06156.13 RLN79697.1 - 9.3 7.0 9.6 2.8 8.6 0.2 3.3 2 1 0 2 2 2 0 Initiation control protein YabA Peptidase_S10 PF00450.22 RLN79698.1 - 4.4e-91 306.4 0.0 6.2e-91 305.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase MtlR PF05068.12 RLN79698.1 - 0.22 11.5 0.0 0.39 10.7 0.0 1.3 1 0 0 1 1 1 0 Mannitol repressor YCII PF03795.14 RLN79699.1 - 4.8e-10 39.7 0.0 5.8e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain HA2 PF04408.23 RLN79700.1 - 4.6e-08 33.3 0.0 1.6e-07 31.6 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Ifi-6-16 PF06140.13 RLN79701.1 - 2.4e-19 69.0 27.3 2.4e-19 69.0 27.3 1.7 1 1 0 1 1 1 1 Interferon-induced 6-16 family Ank_2 PF12796.7 RLN79721.1 - 7.6e-29 100.1 17.4 1.2e-07 32.2 0.0 6.1 2 1 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN79721.1 - 5.8e-24 84.2 12.8 5.6e-08 33.2 0.1 7.5 3 2 4 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN79721.1 - 3.7e-19 66.8 8.2 1.2 9.9 0.0 11.6 11 1 1 12 12 12 5 Ankyrin repeat Ank_5 PF13857.6 RLN79721.1 - 3.2e-18 65.5 17.7 0.077 13.3 0.1 10.5 5 3 7 12 12 12 7 Ankyrin repeats (many copies) DUF5049 PF16468.5 RLN79721.1 - 2.6e-05 24.0 6.1 8.8 6.3 0.0 7.5 5 3 4 9 9 9 1 Domain of unknown function (DUF5049) Ank PF00023.30 RLN79721.1 - 0.00021 21.6 7.6 19 5.9 0.1 8.2 5 3 2 7 7 7 1 Ankyrin repeat DUF3322 PF11795.8 RLN79721.1 - 0.0086 16.1 0.8 0.29 11.1 0.0 3.5 2 2 3 5 5 5 1 Uncharacterized protein conserved in bacteria N-term (DUF3322) DUF4588 PF15251.6 RLN79722.1 - 0.14 11.9 3.3 0.23 11.2 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3704 PF12488.8 RLN79722.1 - 0.45 10.2 2.7 0.27 10.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3704) CD36 PF01130.21 RLN79723.1 - 3e-35 121.7 0.0 6.9e-34 117.2 0.0 2.5 1 1 0 1 1 1 1 CD36 family DUF3512 PF12024.8 RLN79723.1 - 0.071 12.6 0.3 0.13 11.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) DUF4644 PF15486.6 RLN79724.1 - 0.0018 18.0 0.2 0.0038 17.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4644) TAD2 PF18521.1 RLN79724.1 - 0.054 13.5 0.3 0.11 12.6 0.3 1.5 1 0 0 1 1 1 0 Transactivation domain 2 DUF3677 PF12432.8 RLN79754.1 - 4e-09 36.7 0.1 1.4e-08 34.9 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3677) BSP_II PF05432.11 RLN79754.1 - 0.00031 20.5 38.7 0.00031 20.5 38.7 3.2 2 1 0 2 2 2 1 Bone sialoprotein II (BSP-II) DUF3037 PF11236.8 RLN79754.1 - 0.095 13.1 0.3 0.69 10.4 0.3 2.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) Utp14 PF04615.13 RLN79754.1 - 0.49 8.9 63.6 0.99 7.9 63.6 1.5 1 0 0 1 1 1 0 Utp14 protein Methyltransf_25 PF13649.6 RLN79755.1 - 5.6e-16 59.0 0.0 1.1e-15 58.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN79755.1 - 4.1e-12 46.7 0.0 6.3e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN79755.1 - 8.8e-11 42.3 0.0 1.6e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN79755.1 - 4.5e-10 39.6 0.0 6.1e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN79755.1 - 1.2e-09 38.2 0.0 1.6e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN79755.1 - 1.5e-08 34.4 0.0 2.2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 RLN79755.1 - 0.0033 16.7 0.0 0.0085 15.4 0.0 1.6 1 1 1 2 2 2 1 O-methyltransferase domain Ubie_methyltran PF01209.18 RLN79755.1 - 0.0063 15.9 0.0 0.0092 15.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GAS PF13851.6 RLN79756.1 - 1.3e-68 230.3 23.7 1.3e-68 230.3 23.7 3.7 3 1 0 3 3 3 1 Growth-arrest specific micro-tubule binding HTH_Tnp_Tc5 PF03221.16 RLN79757.1 - 0.051 13.6 0.0 0.082 13.0 0.0 1.3 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain HECT PF00632.25 RLN79758.1 - 1.3e-78 264.6 0.0 5e-78 262.7 0.0 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) HAV_VP PF12944.7 RLN79758.1 - 0.088 12.8 0.0 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 Hepatitis A virus viral protein VP Clathrin PF00637.20 RLN79760.1 - 3.3e-179 587.9 39.2 3.6e-29 101.5 1.0 7.7 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 RLN79760.1 - 2.5e-29 101.0 0.6 7.8e-29 99.4 0.6 2.0 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.20 RLN79760.1 - 8.8e-19 66.8 0.2 7e-07 29.3 0.0 5.7 5 0 0 5 5 5 3 Clathrin propeller repeat Clathrin-link PF09268.10 RLN79760.1 - 8.6e-06 25.0 0.2 2.6e-05 23.5 0.2 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Isochorismatase PF00857.20 RLN79760.1 - 0.0025 18.0 0.4 0.14 12.3 0.4 2.8 1 1 0 1 1 1 1 Isochorismatase family TPR_1 PF00515.28 RLN79760.1 - 0.0035 17.1 2.5 2 8.4 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN79760.1 - 0.0088 16.8 0.2 1.9e+02 3.3 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 RLN79760.1 - 0.014 15.3 5.3 13 6.0 0.1 5.5 7 0 0 7 7 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN79760.1 - 0.041 14.1 0.5 1.4 9.2 0.1 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 RLN79760.1 - 0.084 13.0 8.8 2.3 8.6 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN79760.1 - 0.17 12.4 1.4 17 6.0 0.4 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN79760.1 - 0.18 12.1 0.7 18 5.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Clat_adaptor_s PF01217.20 RLN79761.1 - 2.9e-41 140.7 0.7 7.6e-36 123.2 0.2 2.2 2 0 0 2 2 2 2 Clathrin adaptor complex small chain Phage_GP20 PF06810.11 RLN79762.1 - 7.9e-05 22.5 2.1 0.0001 22.2 2.1 1.1 1 0 0 1 1 1 1 Phage minor structural protein GP20 DUF4472 PF14739.6 RLN79762.1 - 0.0096 16.7 2.1 0.012 16.3 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4472) DUF4602 PF15375.6 RLN79762.1 - 0.055 13.8 2.4 0.085 13.2 2.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4602) LPP PF04728.13 RLN79762.1 - 0.12 12.8 4.5 0.76 10.2 4.5 2.2 1 1 0 1 1 1 0 Lipoprotein leucine-zipper Cyt-b5 PF00173.28 RLN79763.1 - 4e-23 81.3 0.0 5.1e-21 74.6 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 RLN79763.1 - 1.4e-12 48.0 1.4 1.4e-12 48.0 1.4 2.4 3 0 0 3 3 3 1 Fatty acid desaturase Jiv90 PF14901.6 RLN79763.1 - 0.013 15.6 0.1 0.037 14.2 0.1 1.7 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone BTB PF00651.31 RLN79764.1 - 4.8e-20 71.8 0.1 9e-20 71.0 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 RLN79764.1 - 2.6e-13 49.9 0.1 4.2e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch DNA_pol_phi PF04931.13 RLN79764.1 - 0.16 10.0 2.5 0.23 9.5 2.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 RLN79764.1 - 1.2 9.2 5.8 0.48 10.5 2.8 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.12 RLN79764.1 - 7.4 5.8 6.7 12 5.1 6.7 1.3 1 0 0 1 1 1 0 NOA36 protein RabGAP-TBC PF00566.18 RLN79765.1 - 7.3e-09 35.6 4.5 0.001 18.7 1.7 3.4 2 1 0 2 2 2 2 Rab-GTPase-TBC domain RWD PF05773.22 RLN79766.1 - 1.1e-15 57.9 5.8 9.5e-15 54.9 4.3 2.5 2 1 0 2 2 2 1 RWD domain Na_H_Exchanger PF00999.21 RLN79767.1 - 4.9e-17 61.8 8.1 7e-17 61.3 8.1 1.2 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family IBN_N PF03810.19 RLN79768.1 - 0.019 14.9 0.2 0.13 12.2 0.3 2.5 2 0 0 2 2 2 0 Importin-beta N-terminal domain PH PF00169.29 RLN79769.1 - 2.8e-07 31.0 0.0 4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 PH domain GBP PF02263.19 RLN79792.1 - 6.9e-30 104.2 2.5 9.2e-17 61.2 0.1 2.3 1 1 0 2 2 2 2 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 RLN79792.1 - 9.1e-06 25.3 0.3 9.1e-06 25.3 0.3 1.8 2 0 0 2 2 2 1 Guanylate-binding protein, C-terminal domain Phage_int_SAM_5 PF13102.6 RLN79792.1 - 0.058 13.7 0.1 0.19 12.1 0.0 1.9 1 1 1 2 2 2 0 Phage integrase SAM-like domain FUSC_2 PF13515.6 RLN79792.1 - 0.11 12.6 0.6 0.23 11.6 0.6 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein-like DUF3322 PF11795.8 RLN79792.1 - 0.12 12.3 1.3 0.25 11.3 0.1 2.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) DNA_pol_phi PF04931.13 RLN79795.1 - 8.3 4.4 9.8 7.9 4.4 9.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi Myb_DNA-binding PF00249.31 RLN79814.1 - 3.2e-10 40.0 0.0 1.3e-09 38.1 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN79814.1 - 6.8e-05 22.7 0.3 6.8e-05 22.7 0.3 2.9 3 0 0 3 3 3 1 Myb DNA-binding like GPS2_interact PF15784.5 RLN79814.1 - 0.00035 20.9 0.4 0.00035 20.9 0.4 3.5 2 0 0 2 2 2 1 G-protein pathway suppressor 2-interacting domain Myb_DNA-bind_6 PF13921.6 RLN79814.1 - 0.00042 20.5 0.3 0.0012 19.0 0.3 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain AhpC-TSA PF00578.21 RLN79815.1 - 9.6e-15 54.6 0.0 1.4e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RLN79815.1 - 5.2e-08 32.7 0.0 6.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 RLN79815.1 - 2.5e-06 27.2 0.2 4.3e-06 26.5 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 RLN79815.1 - 0.18 11.9 0.0 0.25 11.5 0.0 1.4 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme CC2D2AN-C2 PF15625.6 RLN79816.1 - 3.9e-06 26.7 0.0 1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain Clathrin_H_link PF13838.6 RLN79816.1 - 0.015 15.2 1.0 0.052 13.5 1.0 1.9 1 0 0 1 1 1 0 Clathrin-H-link Nbl1_Borealin_N PF10444.9 RLN79817.1 - 4.3e-12 45.5 1.3 4.3e-12 45.5 1.3 2.0 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal Borealin PF10512.9 RLN79817.1 - 0.00041 20.3 0.3 0.00041 20.3 0.3 2.6 2 2 1 3 3 3 1 Cell division cycle-associated protein 8 DUF418 PF04235.12 RLN79817.1 - 0.038 13.9 0.1 0.056 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF418) Gln_amidase PF15644.6 RLN79817.1 - 0.15 13.1 0.6 0.53 11.3 0.6 1.9 1 0 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase FEZ PF07763.13 RLN79817.1 - 0.16 11.7 4.0 0.3 10.8 4.0 1.3 1 0 0 1 1 1 0 FEZ-like protein POX PF07526.11 RLN79817.1 - 2.3 8.8 5.5 0.56 10.8 0.8 2.4 3 0 0 3 3 3 0 Associated with HOX Ribosomal_L36 PF00444.18 RLN79818.1 - 2e-13 50.3 8.7 3e-13 49.7 8.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 AMP-binding PF00501.28 RLN79819.1 - 9e-146 485.8 0.0 1.8e-85 287.1 0.0 3.1 2 1 1 3 3 3 3 AMP-binding enzyme AMP-binding_C PF13193.6 RLN79819.1 - 1.3e-27 96.5 0.7 1.5e-12 48.3 0.0 3.4 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain VitD-bind_III PF09164.10 RLN79819.1 - 2.5e-05 24.2 0.0 0.08 12.9 0.0 2.6 2 0 0 2 2 2 2 Vitamin D binding protein, domain III AMP-binding PF00501.28 RLN79820.1 - 3.2e-05 22.7 0.0 3.6e-05 22.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 RLN79821.1 - 5.2e-68 229.6 0.0 6.7e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN79821.1 - 1.4e-14 54.8 0.9 2.7e-14 53.9 0.3 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 RLN79822.1 - 8.5e-94 314.5 0.0 1.1e-93 314.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN79822.1 - 1.8e-13 51.3 0.1 7.4e-13 49.3 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 RLN79823.1 - 9.9e-91 304.4 0.0 1.2e-90 304.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN79823.1 - 1.6e-14 54.6 1.0 3.3e-14 53.6 0.1 2.1 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain C2 PF00168.30 RLN79841.1 - 7.4e-05 23.0 0.0 0.00017 21.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain C2 PF00168.30 RLN79842.1 - 1.1e-10 41.7 0.0 3.1e-10 40.2 0.0 1.8 1 1 0 1 1 1 1 C2 domain C2 PF00168.30 RLN79843.1 - 5.8e-08 33.0 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain C2 PF00168.30 RLN79844.1 - 1.9e-07 31.3 0.0 7.3e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 C2 domain Podoplanin PF05808.11 RLN79844.1 - 0.58 10.3 3.5 1.6 8.8 3.5 1.7 1 0 0 1 1 1 0 Podoplanin Syntaxin-6_N PF09177.11 RLN79845.1 - 3.1e-09 37.3 7.6 4.1e-09 36.9 0.3 3.3 2 2 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 RLN79845.1 - 0.0028 17.6 0.1 0.012 15.6 0.1 2.1 1 0 0 1 1 1 1 SNARE domain Pkinase PF00069.25 RLN79846.1 - 4.2e-61 206.6 0.0 9.4e-61 205.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN79846.1 - 1.4e-44 152.3 0.0 2.7e-44 151.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RhoGAP PF00620.27 RLN79846.1 - 8e-24 84.2 0.0 1.7e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Pkinase_fungal PF17667.1 RLN79846.1 - 0.00043 19.2 0.5 0.00098 18.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase HSP70 PF00012.20 RLN79848.1 - 2.7e-213 709.5 1.3 3.1e-213 709.3 1.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN79848.1 - 4.6e-14 52.0 0.0 7.3e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.18 RLN79848.1 - 0.016 14.5 0.1 0.04 13.2 0.1 1.7 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase B56 PF01603.20 RLN79915.1 - 2.9e-126 421.8 8.9 2e-124 415.7 8.9 2.7 1 1 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) HSP90 PF00183.18 RLN79962.1 - 1.3e-15 57.3 13.6 1.7e-15 56.9 13.6 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 RLN79962.1 - 9e-15 55.2 0.0 1.3e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 RLN79962.1 - 2.5e-10 40.3 0.3 4.8e-10 39.4 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_pol3_a_NII PF11490.8 RLN79962.1 - 0.028 14.3 7.3 0.048 13.6 7.3 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Methyltransf_11 PF08241.12 RLN79978.1 - 5.5e-14 52.6 0.0 8.3e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN79978.1 - 1.1e-11 45.3 0.1 1.8e-11 44.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN79978.1 - 4.1e-10 39.7 0.0 4.6e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN79978.1 - 2e-08 34.8 0.0 3.2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN79978.1 - 9.3e-05 22.3 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RLN79978.1 - 0.0023 17.4 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 RLN79978.1 - 0.0026 17.1 0.1 0.0036 16.7 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NMO PF03060.15 RLN79978.1 - 0.0052 16.2 0.1 0.0082 15.6 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase CMAS PF02353.20 RLN79978.1 - 0.0057 16.0 0.2 0.0066 15.8 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 RLN79978.1 - 0.02 14.4 0.2 0.042 13.4 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase small domain cNMP_binding PF00027.29 RLN79979.1 - 1.6e-11 44.1 0.0 3.6e-06 26.9 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN79979.1 - 2e-07 30.5 7.2 3.1e-07 29.9 7.2 1.2 1 0 0 1 1 1 1 Ion transport protein MOSC_N PF03476.16 RLN80033.1 - 9.2e-31 106.2 0.0 2e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 RLN80033.1 - 1e-23 83.8 0.0 1.6e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 MOSC domain EFF-AFF PF14884.6 RLN80033.1 - 0.11 10.6 0.0 0.16 10.0 0.0 1.1 1 0 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen Pkinase PF00069.25 RLN80035.1 - 3.5e-39 134.8 0.0 4.8e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN80035.1 - 2.9e-25 89.0 0.0 3.8e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN80035.1 - 3.1e-05 23.4 0.4 0.00018 20.9 0.0 2.1 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN80035.1 - 0.00014 21.9 0.7 0.00027 21.0 0.3 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RLN80035.1 - 0.0076 15.6 0.0 0.015 14.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RLN80035.1 - 0.26 10.2 0.0 0.36 9.7 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain DHR-2 PF06920.13 RLN80036.1 - 1.4e-46 159.3 0.0 3e-44 151.6 0.0 2.2 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 RLN80036.1 - 1.5e-34 119.5 0.0 4.4e-34 118.0 0.0 1.8 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins RNase_PH PF01138.21 RLN80037.1 - 8.8e-31 107.1 0.2 2.7e-30 105.5 0.2 1.9 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 TCR PF03638.15 RLN80037.1 - 4.7e-08 33.2 32.1 1.2e-06 28.7 19.6 2.3 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain RNase_PH_C PF03725.15 RLN80037.1 - 0.0099 15.9 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 CNRIP1 PF15043.6 RLN80037.1 - 0.016 14.8 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 CB1 cannabinoid receptor-interacting protein 1 RGS PF00615.19 RLN80038.1 - 2.3e-70 234.3 8.2 1.4e-17 64.1 4.6 4.9 5 0 0 5 5 5 4 Regulator of G protein signaling domain Pam16 PF03656.13 RLN80038.1 - 2.5e-05 24.3 1.2 6.2e-05 23.0 0.0 2.2 3 0 0 3 3 3 1 Pam16 DnaJ PF00226.31 RLN80038.1 - 0.00019 21.5 0.0 0.00038 20.5 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Acyl-CoA_dh_1 PF00441.24 RLN80039.1 - 2.8e-40 138.0 2.4 3.7e-40 137.6 2.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RLN80039.1 - 1.2e-27 96.0 0.0 1.9e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 RLN80039.1 - 5.4e-17 62.5 0.0 2e-16 60.6 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 RLN80039.1 - 7.9e-16 58.5 0.9 1.2e-15 58.0 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 RLN80039.1 - 0.00046 20.0 0.1 0.0015 18.2 0.1 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal CW_7 PF08230.11 RLN80039.1 - 0.011 15.5 0.4 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 CW_7 repeat Pkinase PF00069.25 RLN80040.1 - 4.6e-48 163.9 0.0 5.3e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN80040.1 - 8.9e-28 97.3 0.0 1.6e-27 96.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RLN80040.1 - 6.1e-05 22.1 0.0 8.7e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 RLN80040.1 - 0.0038 16.1 0.0 0.0051 15.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN80040.1 - 0.028 13.7 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 RLN80040.1 - 0.074 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family AIRS_C PF02769.22 RLN80040.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 AIR synthase related protein, C-terminal domain Transp_Tc5_C PF04236.15 RLN80066.1 - 0.12 12.8 3.7 2.7 8.4 0.8 2.3 1 1 1 2 2 2 0 Tc5 transposase C-terminal domain TMEM70 PF06979.12 RLN80067.1 - 9.9e-25 87.5 1.5 1.9e-23 83.3 1.5 2.1 1 1 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex FOP_dimer PF09398.10 RLN80068.1 - 0.00043 20.5 0.0 0.00099 19.3 0.0 1.6 1 0 0 1 1 1 1 FOP N terminal dimerisation domain HTH_Tnp_Tc5 PF03221.16 RLN80069.1 - 7.1e-07 29.2 0.0 1.6e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 RLN80069.1 - 0.04 13.7 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease RWP-RK PF02042.15 RLN80091.1 - 1.3e-20 73.1 0.1 2.7e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 RLN80092.1 - 1.8e-20 72.6 0.0 4e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 RWP-RK domain DUF4611 PF15387.6 RLN80092.1 - 0.074 13.3 0.5 0.19 12.0 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Cytochrom_C_2 PF01322.20 RLN80092.1 - 0.46 11.4 3.7 0.93 10.4 0.7 2.3 2 0 0 2 2 2 0 Cytochrome C' PDZ PF00595.24 RLN80093.1 - 0.049 14.0 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 RLN80093.1 - 0.08 12.8 0.2 0.89 9.5 0.1 2.3 2 0 0 2 2 2 0 PDZ domain KAR9 PF08580.10 RLN80095.1 - 0.021 13.4 0.9 0.024 13.2 0.9 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 PDZ_assoc PF10600.9 RLN80113.1 - 2 9.3 5.8 2.3 9.1 0.2 2.8 3 0 0 3 3 3 0 PDZ-associated domain of NMDA receptors Pkinase PF00069.25 RLN80114.1 - 6.3e-20 71.6 0.0 1.2e-09 37.9 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN80114.1 - 1e-09 38.1 1.4 0.00081 18.7 0.1 2.9 1 1 1 2 2 2 2 Protein tyrosine kinase LRR_6 PF13516.6 RLN80115.1 - 4.2e-09 35.7 14.0 2.3e-05 24.1 0.1 4.8 5 0 0 5 5 5 3 Leucine Rich repeat LRR_8 PF13855.6 RLN80115.1 - 0.021 14.5 10.6 0.32 10.8 5.8 4.0 2 1 1 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 RLN80115.1 - 0.048 14.2 3.8 73 4.5 0.3 4.5 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 RLN80115.1 - 0.33 11.5 12.5 2.3 8.8 1.8 4.1 2 1 3 5 5 5 0 Leucine Rich repeats (2 copies) UPF0220 PF05255.11 RLN80116.1 - 8.1e-24 84.0 7.8 1.3e-15 57.3 2.1 2.0 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0220) DUF3042 PF11240.8 RLN80116.1 - 1.5 8.9 5.3 6.5 6.9 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3042) HEAT PF02985.22 RLN80117.1 - 1.6e-06 27.8 10.1 0.26 11.7 0.0 5.6 6 0 0 6 6 6 3 HEAT repeat Vac14_Fab1_bd PF12755.7 RLN80117.1 - 0.029 15.0 0.0 1.6 9.4 0.0 3.5 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 RLN80117.1 - 0.036 14.6 2.3 4.6 7.8 0.2 4.0 4 1 2 6 6 6 0 HEAT-like repeat CLASP_N PF12348.8 RLN80117.1 - 0.081 12.5 0.0 3.7 7.0 0.0 3.0 3 0 0 3 3 3 0 CLASP N terminal TAF6_C PF07571.13 RLN80117.1 - 0.13 12.6 0.0 0.66 10.3 0.0 2.3 2 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain PH PF00169.29 RLN80123.1 - 0.013 16.0 0.0 0.016 15.7 0.0 1.1 1 0 0 1 1 1 0 PH domain P34-Arc PF04045.14 RLN80125.1 - 5.8e-52 176.8 0.0 1.3e-46 159.3 0.0 2.6 1 1 1 2 2 2 2 Arp2/3 complex, 34 kD subunit p34-Arc tRNA_bind PF01588.20 RLN80125.1 - 3.4e-22 78.4 0.4 7e-22 77.3 0.4 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain DUF935 PF06074.12 RLN80125.1 - 0.21 10.3 0.0 0.29 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) PI3_PI4_kinase PF00454.27 RLN80149.1 - 1.5e-29 103.6 0.3 5.3e-26 92.0 0.3 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FYVE PF01363.21 RLN80149.1 - 5.5e-18 64.9 3.5 1.9e-17 63.2 2.8 2.3 1 1 0 1 1 1 1 FYVE zinc finger PI3Ka PF00613.20 RLN80149.1 - 2.4e-08 33.6 0.3 0.00012 21.5 0.1 2.4 2 0 0 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) F-box-like PF12937.7 RLN80149.1 - 0.03 14.2 0.2 0.079 12.9 0.2 1.8 1 0 0 1 1 1 0 F-box-like DUF4135 PF13575.6 RLN80149.1 - 0.064 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Elf1 PF05129.13 RLN80149.1 - 0.11 12.6 1.1 0.26 11.4 1.1 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like TB2_DP1_HVA22 PF03134.19 RLN80150.1 - 5e-31 106.5 6.2 8.3e-31 105.8 6.2 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF3040 PF11239.8 RLN80150.1 - 0.049 13.9 0.5 0.08 13.2 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) NARP1 PF12569.8 RLN80151.1 - 3.2e-190 633.4 27.1 4.7e-190 632.9 24.2 2.1 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_8 PF13181.6 RLN80151.1 - 5.8e-18 63.5 6.5 6.7e-05 22.8 0.0 7.3 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 RLN80151.1 - 7.7e-13 48.1 11.4 0.058 14.2 0.0 7.8 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN80151.1 - 1.2e-12 46.8 27.9 5.7e-05 22.9 0.0 8.6 10 1 1 11 11 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN80151.1 - 2.3e-12 47.0 4.9 0.0011 19.1 0.1 4.2 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 RLN80151.1 - 2.5e-12 46.1 21.5 1.4e-05 24.7 0.1 7.4 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN80151.1 - 2.3e-11 42.9 7.5 0.011 15.7 0.0 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 RLN80151.1 - 1.6e-08 34.7 14.2 0.038 14.3 0.5 6.7 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 RLN80151.1 - 2.2e-08 33.7 6.9 5.8e-05 22.7 0.2 3.7 4 0 0 4 4 4 2 TPR repeat TPR_19 PF14559.6 RLN80151.1 - 6e-08 33.1 20.0 0.0035 17.8 0.0 6.5 6 1 1 7 7 6 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN80151.1 - 1e-07 31.9 9.5 0.4 10.8 0.0 5.1 4 0 0 4 4 4 3 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 RLN80151.1 - 3.8e-06 27.0 0.4 1.5 9.0 0.3 5.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN80151.1 - 5.1e-06 27.0 17.8 0.28 11.9 0.0 7.7 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN80151.1 - 1.9e-05 24.7 2.8 2.1 8.9 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN80151.1 - 0.003 18.1 12.4 13 6.6 0.0 6.3 6 0 0 6 6 5 0 Tetratricopeptide repeat Arm_3 PF16186.5 RLN80151.1 - 0.088 12.4 0.0 0.39 10.3 0.2 2.0 2 0 0 2 2 2 0 Atypical Arm repeat TPR_10 PF13374.6 RLN80151.1 - 0.64 10.0 16.1 2.5 8.1 0.5 6.2 8 0 0 8 8 7 0 Tetratricopeptide repeat YqfQ PF14181.6 RLN80151.1 - 5.5 7.2 10.2 10 6.3 10.2 1.4 1 0 0 1 1 1 0 YqfQ-like protein DUF2229 PF09989.9 RLN80151.1 - 8 6.1 10.1 7.6 6.1 0.0 2.8 3 0 0 3 3 3 0 CoA enzyme activase uncharacterised domain (DUF2229) TPR_4 PF07721.14 RLN80151.1 - 8.5 7.3 8.1 80 4.3 0.1 5.5 7 0 0 7 7 5 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 RLN80152.1 - 5.2e-07 29.7 0.3 7.9e-07 29.2 0.3 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN80152.1 - 0.00012 22.3 0.1 0.00019 21.6 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4698 PF15769.5 RLN80152.1 - 0.24 10.4 1.6 0.33 10.0 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Ion_trans PF00520.31 RLN80153.1 - 6.3e-148 490.6 66.5 5.8e-46 156.7 9.6 4.1 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 RLN80153.1 - 2.3e-09 36.5 58.8 9.5e-05 21.2 12.7 7.2 6 2 1 7 7 7 5 Polycystin cation channel SR-25 PF10500.9 RLN80153.1 - 0.00055 19.6 8.2 0.00055 19.6 8.2 3.0 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein SelP_N PF04592.14 RLN80153.1 - 5.4 6.4 12.2 10 5.4 12.2 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DHC_N2 PF08393.13 RLN80154.1 - 1.4e-15 57.3 0.0 1.6e-14 53.9 0.0 2.4 1 1 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_22 PF13401.6 RLN80154.1 - 6.5e-09 36.2 0.3 0.006 16.9 0.0 4.6 4 0 0 4 4 3 2 AAA domain AAA_6 PF12774.7 RLN80154.1 - 2e-08 33.6 0.0 0.00018 20.6 0.1 4.0 2 1 1 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 RLN80154.1 - 4.3e-07 29.6 0.0 0.017 14.6 0.0 3.4 3 0 0 3 3 3 2 P-loop containing dynein motor region HTH_Tnp_1 PF01527.20 RLN80154.1 - 1.9e-05 24.9 4.5 2.2e-05 24.7 0.2 3.5 2 0 0 2 2 2 1 Transposase AAA PF00004.29 RLN80154.1 - 4.1e-05 24.0 0.0 0.66 10.4 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 RLN80154.1 - 0.00081 19.1 0.1 0.13 12.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 RLN80154.1 - 0.0011 19.2 4.4 0.79 9.9 0.0 5.0 5 0 0 5 5 5 1 AAA domain AAA_16 PF13191.6 RLN80154.1 - 0.0015 18.9 0.0 0.008 16.6 0.0 7.8 8 1 1 9 9 4 2 AAA ATPase domain HTH_28 PF13518.6 RLN80154.1 - 0.0016 18.6 0.3 0.0091 16.1 0.3 2.5 1 0 0 1 1 1 1 Helix-turn-helix domain AAA_18 PF13238.6 RLN80154.1 - 0.0078 16.8 0.1 1.4 9.4 0.0 3.5 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.27 RLN80154.1 - 0.0084 16.6 0.0 2.9 8.4 0.0 2.9 2 0 0 2 2 2 1 ABC transporter AAA_30 PF13604.6 RLN80154.1 - 0.01 15.6 0.0 4.2 7.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RLN80154.1 - 0.011 15.6 0.4 5.5 6.9 0.0 4.6 4 0 0 4 4 4 0 NACHT domain HTH_23 PF13384.6 RLN80154.1 - 0.016 15.0 1.3 0.1 12.5 0.1 3.2 2 0 0 2 2 1 0 Homeodomain-like domain AAA_19 PF13245.6 RLN80154.1 - 0.017 15.5 0.4 7.7 6.8 0.0 4.3 5 0 0 5 5 3 0 AAA domain AAA_24 PF13479.6 RLN80154.1 - 0.018 14.8 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_8 PF12780.7 RLN80154.1 - 0.039 13.3 0.0 7.3 5.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 AAA_23 PF13476.6 RLN80154.1 - 0.048 14.1 0.0 4.9 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain HTH_Tnp_ISL3 PF13542.6 RLN80154.1 - 0.058 12.8 0.0 0.26 10.8 0.0 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Glyco_transf_43 PF03360.16 RLN80154.1 - 0.063 13.1 0.0 2.5 7.9 0.0 2.8 2 0 0 2 2 2 0 Glycosyltransferase family 43 AAA_11 PF13086.6 RLN80154.1 - 0.081 12.7 0.0 0.43 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 RLN80154.1 - 0.11 11.9 0.0 0.28 10.6 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Mg_chelatase PF01078.21 RLN80154.1 - 0.13 11.6 0.0 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI cobW PF02492.19 RLN80154.1 - 0.13 11.8 0.0 5.7 6.5 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain S1 PF00575.23 RLN80155.1 - 1.1e-14 54.6 12.7 1.1e-11 44.9 1.3 3.6 4 1 0 4 4 4 2 S1 RNA binding domain TPR_19 PF14559.6 RLN80155.1 - 6e-08 33.1 2.1 0.0027 18.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat Suf PF05843.14 RLN80155.1 - 5.5e-07 29.9 1.3 5.5e-07 29.9 1.3 3.7 2 2 2 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 RLN80155.1 - 4.2e-05 24.0 7.7 0.49 11.3 0.0 5.4 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 RLN80155.1 - 0.0014 19.1 2.3 0.072 13.8 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN80155.1 - 0.019 15.6 4.1 0.021 15.5 0.2 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat Lin-8 PF03353.15 RLN80155.1 - 0.26 10.8 13.3 0.47 10.0 13.3 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SAPS PF04499.15 RLN80155.1 - 4.1 6.1 13.2 7.2 5.3 13.2 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 RLN80155.1 - 5.4 6.2 36.6 10 5.3 36.6 1.4 1 0 0 1 1 1 0 BUD22 GET2 PF08690.10 RLN80155.1 - 7.1 6.2 11.1 12 5.5 11.1 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 MtN3_slv PF03083.16 RLN80180.1 - 3.8e-24 84.5 13.9 2e-14 53.4 6.3 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PIG-P PF08510.12 RLN80180.1 - 0.0067 16.3 4.5 0.31 11.0 0.2 2.3 1 1 1 2 2 2 2 PIG-P HhH-GPD PF00730.25 RLN80181.1 - 2.5e-13 50.4 0.0 4.1e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 RLN80181.1 - 2.7e-06 26.9 0.0 5.7e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_Tnp_Tc5 PF03221.16 RLN80182.1 - 1.6e-05 24.9 0.0 3.8e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF2582 PF10771.9 RLN80182.1 - 0.014 15.6 0.0 0.05 13.8 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix domain (DUF2582) Adaptin_N PF01602.20 RLN80183.1 - 4.8e-101 338.9 0.8 1.5e-100 337.2 0.8 1.7 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 RLN80183.1 - 3.4e-44 150.8 5.1 3.1e-42 144.3 0.1 3.2 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 RLN80183.1 - 3.2e-19 69.1 0.0 1e-18 67.4 0.0 1.9 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 RLN80183.1 - 4.3e-10 39.8 5.3 0.099 13.0 0.0 6.5 4 3 3 7 7 7 3 HEAT repeats HEAT PF02985.22 RLN80183.1 - 4.1e-07 29.7 6.0 5.3 7.6 0.0 6.2 6 0 0 6 6 6 3 HEAT repeat Arm_2 PF04826.13 RLN80183.1 - 0.00028 20.4 0.7 0.0015 18.0 0.2 2.3 1 1 1 2 2 2 1 Armadillo-like Na_Ca_ex_C PF16494.5 RLN80183.1 - 0.011 16.1 0.3 0.061 13.8 0.1 2.2 2 0 0 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain Arm PF00514.23 RLN80183.1 - 0.1 12.7 0.2 0.61 10.2 0.0 2.5 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat ABC2_membrane_3 PF12698.7 RLN80184.1 - 9.6e-50 169.6 43.8 3.7e-31 108.5 12.3 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 RLN80184.1 - 2.3e-27 96.2 0.0 4.1e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN80184.1 - 1.1e-09 38.6 0.2 5.5e-06 26.4 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RLN80184.1 - 0.0025 18.3 0.0 0.0047 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 RLN80184.1 - 0.0029 17.3 0.3 0.0062 16.3 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN80184.1 - 0.0053 16.7 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 RLN80184.1 - 0.088 12.5 0.0 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 RLN80184.1 - 0.13 11.7 0.4 2.1 7.7 0.2 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SMC_N PF02463.19 RLN80184.1 - 0.14 11.6 0.1 2.3 7.6 0.1 2.3 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain PHO4 PF01384.20 RLN80184.1 - 3.3 6.6 9.8 0.024 13.7 0.8 1.9 2 0 0 2 2 2 0 Phosphate transporter family FYVE PF01363.21 RLN80213.1 - 3.8e-12 46.2 12.2 7.6e-12 45.2 12.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger Ank_5 PF13857.6 RLN80213.1 - 6.8e-06 26.3 1.6 0.001 19.3 0.5 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN80213.1 - 0.0011 19.5 0.1 0.007 16.9 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN80213.1 - 0.0082 16.7 0.9 0.22 12.2 0.5 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN80213.1 - 0.077 13.6 1.0 7.8 7.4 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 RLN80213.1 - 2.9 8.5 9.0 23 5.7 0.2 3.3 2 1 1 3 3 3 0 Ankyrin repeat LsmAD PF06741.13 RLN80214.1 - 1.5e-24 86.3 1.3 3.4e-24 85.2 1.3 1.6 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 RLN80214.1 - 5.7e-12 45.6 0.0 1.4e-11 44.3 0.0 1.7 2 0 0 2 2 2 1 Ataxin 2 SM domain PAM2 PF07145.15 RLN80214.1 - 1.4e-05 24.5 2.6 0.006 16.2 0.5 2.7 1 1 1 2 2 2 2 Ataxin-2 C-terminal region DnaJ PF00226.31 RLN80215.1 - 5.4e-25 87.3 4.3 1.1e-24 86.3 4.3 1.5 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 RLN80215.1 - 4.1e-09 36.4 0.1 1.3e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Sigma70_ner PF04546.13 RLN80215.1 - 0.0018 18.2 1.6 0.74 9.7 0.0 2.6 3 0 0 3 3 3 2 Sigma-70, non-essential region Sfi1 PF08457.10 RLN80215.1 - 0.046 12.3 1.7 0.089 11.3 1.7 1.4 1 0 0 1 1 1 0 Sfi1 spindle body protein zf-RING_4 PF14570.6 RLN80216.1 - 3.4e-07 29.9 1.3 6.5e-07 29.1 1.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 RLN80216.1 - 0.0011 18.8 0.0 0.0026 17.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 RLN80216.1 - 0.08 13.6 0.2 0.19 12.4 0.2 1.6 1 0 0 1 1 1 0 Torus domain FYVE PF01363.21 RLN80218.1 - 7.2e-05 22.8 0.3 0.00015 21.8 0.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger Caps_synth_GfcC PF06251.11 RLN80219.1 - 0.017 14.7 0.5 0.017 14.7 0.5 3.3 3 1 0 3 3 3 0 Capsule biosynthesis GfcC TMEM247 PF15444.6 RLN80219.1 - 0.02 15.0 1.5 0.02 15.0 1.5 2.5 2 0 0 2 2 2 0 Transmembrane protein 247 Baculo_PEP_C PF04513.12 RLN80219.1 - 1.2 9.2 15.1 0.64 10.1 1.1 4.4 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2158 PF09926.9 RLN80220.1 - 0.098 12.4 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2158) Pkinase PF00069.25 RLN80221.1 - 1.8e-49 168.5 0.0 2.6e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN80221.1 - 8.4e-45 153.1 0.0 1.1e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3430 PF11912.8 RLN80221.1 - 0.007 16.4 4.2 0.007 16.4 4.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3430) SKG6 PF08693.10 RLN80221.1 - 0.03 13.7 0.2 0.03 13.7 0.2 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Haspin_kinase PF12330.8 RLN80221.1 - 0.051 12.5 0.0 0.11 11.5 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain DUF4841 PF16129.5 RLN80221.1 - 0.1 12.8 0.4 12 6.2 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4841) PTP_tm PF18861.1 RLN80221.1 - 0.12 12.4 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J MLANA PF14991.6 RLN80221.1 - 0.13 12.6 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A DSPn PF14671.6 RLN80247.1 - 2.8e-32 112.1 0.0 3.3e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half Skp1 PF01466.19 RLN80248.1 - 8.7e-22 77.0 0.3 1.5e-21 76.3 0.3 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 RLN80248.1 - 5e-18 65.0 0.1 9.4e-18 64.1 0.1 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain NPP1 PF05630.11 RLN80249.1 - 2.2e-76 256.4 0.0 2.5e-76 256.2 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) C2 PF00168.30 RLN80250.1 - 7.8e-55 183.5 0.0 7.9e-17 61.4 0.0 5.3 5 0 0 5 5 5 5 C2 domain CEP76-C2 PF15627.6 RLN80250.1 - 0.026 14.1 0.0 0.08 12.5 0.0 1.9 1 0 0 1 1 1 0 CEP76 C2 domain SPRY PF00622.28 RLN80269.1 - 1.7e-12 47.5 0.1 3.1e-12 46.6 0.1 1.5 1 0 0 1 1 1 1 SPRY domain tRNA-synt_1g PF09334.11 RLN80270.1 - 2.1e-56 191.4 0.0 3e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.20 RLN80270.1 - 2.9e-28 97.8 0.0 5.4e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.22 RLN80270.1 - 5.1e-23 81.2 0.1 3.6e-22 78.4 0.0 1.9 1 1 1 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 RLN80270.1 - 3e-05 24.0 0.2 5.9e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 RLN80270.1 - 4.2e-05 23.0 0.0 7.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 RLN80270.1 - 0.0049 15.8 0.0 0.0084 15.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (K) NDC10_II PF16787.5 RLN80271.1 - 2e-33 115.8 0.0 6e-32 111.0 0.0 2.5 1 1 0 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 RLN80271.1 - 7e-17 61.5 0.0 1.8e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes ABC2_membrane_3 PF12698.7 RLN80272.1 - 4.2e-45 154.4 16.3 7.4e-45 153.6 16.3 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 RLN80272.1 - 9.7e-27 94.2 0.0 1.7e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN80272.1 - 3.1e-08 33.8 1.4 9.4e-07 28.9 0.0 2.6 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RLN80272.1 - 0.0064 16.2 0.0 0.059 13.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_2 PF12679.7 RLN80272.1 - 0.049 12.9 17.7 3.1 7.0 0.0 2.7 2 1 0 2 2 2 0 ABC-2 family transporter protein DUF4162 PF13732.6 RLN80272.1 - 0.08 13.7 0.0 13 6.6 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4162) CrgA PF06781.12 RLN80272.1 - 0.24 11.5 3.4 0.21 11.6 1.1 2.1 2 0 0 2 2 2 0 Cell division protein CrgA GDA1_CD39 PF01150.17 RLN80274.1 - 1.6e-11 43.6 0.0 2.2e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Orai-1 PF07856.12 RLN80314.1 - 2.9e-20 72.7 8.9 2.9e-20 72.7 8.9 1.6 2 0 0 2 2 2 1 Mediator of CRAC channel activity DHHC PF01529.20 RLN80314.1 - 0.0013 18.8 7.6 0.0024 18.0 0.0 3.1 3 1 0 3 3 3 1 DHHC palmitoyltransferase RCC1 PF00415.18 RLN80315.1 - 1.9e-38 130.9 8.1 2.5e-11 44.0 0.1 6.5 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN80315.1 - 2.7e-28 97.2 22.2 1.6e-10 40.5 1.3 6.5 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Acyl_CoA_thio PF02551.15 RLN80315.1 - 0.053 13.4 0.0 1 9.2 0.0 2.8 3 0 0 3 3 3 0 Acyl-CoA thioesterase Methyltr_RsmB-F PF01189.17 RLN80336.1 - 7.2e-29 100.9 1.0 4e-15 56.0 0.2 3.2 3 0 0 3 3 3 2 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 RLN80336.1 - 2.9e-06 27.9 0.7 0.00032 21.3 0.0 3.7 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN80336.1 - 4.8e-06 26.5 0.1 0.0013 18.6 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain FtsJ PF01728.19 RLN80336.1 - 0.0001 22.5 0.0 0.0016 18.6 0.0 2.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 RLN80336.1 - 0.0052 17.4 0.0 2.5 8.8 0.0 3.6 3 0 0 3 3 3 1 Methyltransferase domain Fibrillarin PF01269.17 RLN80336.1 - 0.0068 15.5 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Fibrillarin Ubie_methyltran PF01209.18 RLN80336.1 - 0.029 13.7 0.0 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 RLN80336.1 - 0.045 13.5 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 RLN80336.1 - 0.07 13.0 0.0 0.99 9.2 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Ribosomal_S25 PF03297.15 RLN80336.1 - 0.14 12.4 0.3 0.26 11.5 0.3 1.4 1 0 0 1 1 1 0 S25 ribosomal protein Transp_cyt_pur PF02133.15 RLN80337.1 - 7e-46 156.9 35.1 8.6e-46 156.6 35.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ETF_QO PF05187.13 RLN80354.1 - 9.5e-37 125.3 0.1 1.6e-36 124.6 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 RLN80354.1 - 6.2e-05 22.3 0.8 0.0022 17.1 1.1 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 RLN80354.1 - 8.4e-05 21.9 0.0 0.013 14.8 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 RLN80354.1 - 0.00079 19.1 2.6 0.065 12.8 2.6 2.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 RLN80354.1 - 0.0045 16.1 0.1 0.007 15.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Fer4_7 PF12838.7 RLN80354.1 - 0.0052 17.3 3.0 0.015 15.8 3.0 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain NAD_binding_8 PF13450.6 RLN80354.1 - 0.0095 16.1 0.0 0.0095 16.1 0.0 2.7 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 RLN80354.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding Tom7 PF08038.12 RLN80354.1 - 0.017 14.8 0.2 0.043 13.5 0.2 1.6 1 0 0 1 1 1 0 TOM7 family Pyr_redox_2 PF07992.14 RLN80354.1 - 0.018 14.3 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RLN80354.1 - 0.071 11.8 0.3 0.12 11.1 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 RLN80354.1 - 0.1 11.8 0.2 0.16 11.2 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RLN80354.1 - 0.21 10.7 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 RLN80354.1 - 0.25 11.9 1.2 6.5 7.4 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.6 RLN80355.1 - 3.8e-15 56.1 0.0 5.3e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN80355.1 - 9.2e-15 55.2 0.0 2.1e-14 54.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN80355.1 - 8.9e-14 52.0 0.0 1.8e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN80355.1 - 9.2e-09 35.8 0.0 1.6e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN80355.1 - 1.2e-08 34.9 0.0 2.4e-08 33.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 RLN80355.1 - 7.7e-06 25.6 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 RLN80355.1 - 0.0041 17.0 0.1 0.032 14.1 0.1 2.0 1 1 0 1 1 1 1 Hypothetical methyltransferase NNMT_PNMT_TEMT PF01234.17 RLN80355.1 - 0.0044 16.3 0.1 0.02 14.1 0.0 2.0 3 0 0 3 3 3 1 NNMT/PNMT/TEMT family Methyltransf_2 PF00891.18 RLN80355.1 - 0.024 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_PK PF05891.12 RLN80355.1 - 0.056 13.0 0.0 0.094 12.2 0.0 1.4 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Peptidase_S10 PF00450.22 RLN80356.1 - 5.7e-66 223.6 0.0 6.4e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 RLN80356.1 - 0.001 19.8 0.0 0.0084 16.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN80356.1 - 0.03 13.6 0.0 0.2 10.9 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 BAAT_C PF08840.11 RLN80356.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal MSG PF02349.15 RLN80356.1 - 0.18 12.0 1.1 0.34 11.1 1.1 1.4 1 0 0 1 1 1 0 Major surface glycoprotein Myb_DNA-binding PF00249.31 RLN80358.1 - 1e-09 38.5 0.2 0.00014 22.0 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN80358.1 - 2e-05 24.7 0.2 0.00069 19.8 0.0 2.6 1 1 1 2 2 2 1 Myb-like DNA-binding domain SLIDE PF09111.10 RLN80358.1 - 0.034 14.2 0.0 0.088 12.8 0.0 1.6 1 0 0 1 1 1 0 SLIDE SCIMP PF15050.6 RLN80358.1 - 0.074 13.5 3.4 3.4 8.1 0.0 2.9 3 0 0 3 3 3 0 SCIMP protein RNR_Alpha PF17975.1 RLN80359.1 - 6.4e-40 135.7 0.1 2e-39 134.2 0.2 1.8 2 0 0 2 2 2 1 Ribonucleotide reductase alpha domain Ribonuc_red_lgC PF02867.15 RLN80359.1 - 1.8e-09 36.7 0.0 0.0017 17.0 0.1 3.3 3 0 0 3 3 3 3 Ribonucleotide reductase, barrel domain ABC2_membrane PF01061.24 RLN80360.1 - 8.3e-27 94.0 25.8 8.3e-27 94.0 25.8 1.6 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN80360.1 - 4.2e-12 45.8 0.3 2.6e-10 40.1 0.0 3.1 3 0 0 3 3 3 1 CDR ABC transporter PDR_assoc PF08370.11 RLN80360.1 - 0.024 14.4 1.1 0.11 12.2 0.0 2.6 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Hormone_3 PF00159.18 RLN80360.1 - 0.15 12.1 0.2 2.2 8.4 0.0 2.6 2 0 0 2 2 2 0 Pancreatic hormone peptide DnaJ_C PF01556.18 RLN80361.1 - 2.6e-37 128.2 0.2 3.5e-37 127.7 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RLN80361.1 - 1.5e-27 95.5 1.2 5.3e-27 93.7 1.5 1.8 2 0 0 2 2 2 1 DnaJ domain ADAM_spacer1 PF05986.14 RLN80361.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 ADAM-TS Spacer 1 SMP_LBD PF17047.5 RLN80362.1 - 7.4e-12 45.1 0.8 1.2e-11 44.4 0.1 1.7 2 0 0 2 2 2 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 RLN80362.1 - 2.2e-07 31.1 0.5 1.5e-05 25.2 0.0 3.0 2 1 1 3 3 3 1 C2 domain DUF4381 PF14316.6 RLN80362.1 - 0.047 13.9 1.1 0.11 12.8 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Peptidase_C48 PF02902.19 RLN80385.1 - 1.6e-06 28.1 0.0 2.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PB1 PF00564.24 RLN80386.1 - 1.3e-09 37.8 0.0 4.2e-09 36.2 0.0 1.9 2 1 0 2 2 2 1 PB1 domain DEAD PF00270.29 RLN80387.1 - 4.1e-08 33.2 0.0 3e-07 30.4 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Aldo_ket_red PF00248.21 RLN80412.1 - 1e-65 221.9 0.0 1.2e-65 221.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PX PF00787.24 RLN80414.1 - 1.2e-08 34.9 0.0 1.6e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 PX domain Dimer_Tnp_hAT PF05699.14 RLN80437.1 - 4.9e-12 45.5 0.0 9.2e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RCC1_2 PF13540.6 RLN80460.1 - 0.00039 20.1 23.9 0.0031 17.3 2.4 4.1 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat cNMP_binding PF00027.29 RLN80461.1 - 0.0039 17.2 0.0 0.0098 15.9 0.0 1.7 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Peptidase_M20 PF01546.28 RLN80462.1 - 4.3e-27 95.2 0.0 5.8e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 RLN80462.1 - 8.1e-09 35.4 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 RLN80462.1 - 0.0075 16.0 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M28 APH PF01636.23 RLN80463.1 - 5e-41 141.2 0.0 9.6e-41 140.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.24 RLN80463.1 - 3.9e-36 124.5 4.0 7.3e-36 123.6 4.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RLN80463.1 - 6.4e-18 64.7 0.0 1.3e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RLN80463.1 - 3e-12 47.0 5.5 6e-12 46.0 3.5 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RLN80463.1 - 8.1e-08 32.9 0.0 1.8e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain EcKinase PF02958.20 RLN80463.1 - 0.00018 20.9 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 RLN80463.1 - 0.0051 16.4 0.0 0.44 10.1 0.0 2.4 2 0 0 2 2 2 1 RIO1 family DUF1679 PF07914.11 RLN80463.1 - 0.13 11.1 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Cwf_Cwc_15 PF04889.12 RLN80464.1 - 5.9 6.5 8.2 1.4 8.5 4.9 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ins_P5_2-kin PF06090.12 RLN80465.1 - 2.8e-92 309.7 0.4 4.5e-92 309.0 0.4 1.3 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase MPM1 PF17234.2 RLN80465.1 - 0.0008 19.7 0.7 0.0015 18.8 0.7 1.4 1 0 0 1 1 1 1 Mitochondrial peculiar membrane protein 1 DUF4632 PF15451.6 RLN80465.1 - 0.047 13.8 0.1 0.047 13.8 0.1 3.6 4 1 0 4 4 4 0 Domain of unknown function (DUF4632) Cwf_Cwc_15 PF04889.12 RLN80465.1 - 0.097 12.4 14.4 0.043 13.5 11.5 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 RLN80465.1 - 1 8.9 13.1 0.14 11.7 9.0 1.6 2 0 0 2 2 2 0 PPP4R2 BORG_CEP PF14957.6 RLN80465.1 - 2.8 9.1 8.2 9 7.5 8.2 1.9 1 0 0 1 1 1 0 Cdc42 effector Acyl-CoA_dh_1 PF00441.24 RLN80466.1 - 3e-48 163.8 3.4 4.3e-48 163.3 3.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RLN80466.1 - 1e-28 99.3 0.4 2.3e-28 98.2 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RLN80466.1 - 8.1e-24 84.4 1.9 1.1e-23 83.9 1.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 RLN80466.1 - 1.2e-05 25.1 0.0 4.1e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Pkinase PF00069.25 RLN80467.1 - 9.3e-64 215.3 0.0 1.2e-63 214.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN80467.1 - 4.4e-29 101.6 0.0 6.3e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN80467.1 - 8.9e-06 25.2 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RLN80467.1 - 0.012 14.6 0.1 0.02 13.8 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 RLN80467.1 - 0.032 13.0 0.0 0.097 11.4 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 RLN80467.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4230 PF14014.6 RLN80468.1 - 0.025 14.9 0.2 0.036 14.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) Gln-synt_C PF00120.24 RLN80469.1 - 3.5e-67 226.9 0.0 4.7e-67 226.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Ank_2 PF12796.7 RLN80470.1 - 1.1e-33 115.6 8.3 8.5e-07 29.5 0.0 7.0 3 2 4 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN80470.1 - 4.5e-31 106.8 15.3 1.6e-06 28.6 0.1 10.0 4 2 7 12 12 12 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN80470.1 - 3.7e-27 94.0 24.9 0.0063 16.8 0.1 14.0 6 3 9 15 15 15 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN80470.1 - 7.3e-16 56.7 7.0 6.1 7.7 0.0 13.6 13 1 1 14 14 14 1 Ankyrin repeat CLTH PF10607.9 RLN80470.1 - 4.6e-11 42.8 0.0 1.2e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Ank PF00023.30 RLN80470.1 - 0.00058 20.2 0.3 64 4.2 0.0 6.8 5 2 1 6 6 6 0 Ankyrin repeat Phospholip_A2_3 PF09056.11 RLN80470.1 - 0.0088 16.7 0.3 0.029 15.0 0.3 1.9 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 Thioredoxin_4 PF13462.6 RLN80471.1 - 0.37 11.0 4.6 0.37 10.9 0.1 3.0 2 1 1 3 3 3 0 Thioredoxin PX PF00787.24 RLN80472.1 - 8.1e-14 51.6 0.3 1.9e-13 50.3 0.1 1.7 1 1 1 2 2 2 1 PX domain zf-RING_2 PF13639.6 RLN80472.1 - 1.2e-11 44.8 10.4 3.3e-11 43.3 10.4 1.8 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RLN80472.1 - 4.8e-10 39.6 7.4 8.5e-10 38.8 7.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 RLN80472.1 - 6.1e-07 29.2 7.5 7.2e-07 28.9 2.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RLN80472.1 - 2.3e-06 27.6 2.6 4.4e-06 26.7 2.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 RLN80472.1 - 4.9e-06 26.2 7.4 0.00037 20.2 7.4 2.7 1 1 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 RLN80472.1 - 9.2e-06 25.4 9.2 1.2e-05 25.1 7.9 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN80472.1 - 4e-05 23.5 4.1 8.5e-05 22.5 4.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN80472.1 - 0.00028 20.8 7.4 0.00028 20.8 7.4 1.9 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RLN80472.1 - 0.0015 18.3 10.5 0.0044 16.8 9.9 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 RLN80472.1 - 0.0035 17.2 0.2 0.0035 17.2 0.2 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 RLN80472.1 - 0.021 14.4 1.9 0.021 14.4 1.9 1.9 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 RLN80472.1 - 0.045 13.9 9.4 0.35 11.1 9.4 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zinc_ribbon_16 PF17034.5 RLN80472.1 - 0.18 12.0 4.8 0.33 11.2 4.8 1.6 1 1 0 1 1 1 0 Zinc-ribbon like family Prok-RING_4 PF14447.6 RLN80472.1 - 0.3 11.0 11.7 0.53 10.2 9.8 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 RLN80472.1 - 2.3 8.1 11.5 25 4.7 10.0 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Cellulase PF00150.18 RLN80473.1 - 1.3e-27 97.0 1.1 1.7e-27 96.6 1.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Peptidase_S8 PF00082.22 RLN80474.1 - 7.1e-41 140.4 2.5 1.1e-40 139.8 1.0 2.0 1 1 1 2 2 2 1 Subtilase family FAD_binding_2 PF00890.24 RLN80475.1 - 3.5e-75 253.7 1.7 4.6e-75 253.3 1.7 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 RLN80475.1 - 6.4e-08 32.2 1.5 0.0018 17.6 1.1 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RLN80475.1 - 5.8e-05 22.8 0.5 0.00012 21.7 0.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 RLN80475.1 - 7.1e-05 22.1 3.2 0.012 14.7 0.4 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A Succ_DH_flav_C PF02910.20 RLN80475.1 - 0.0073 16.3 0.1 0.021 14.8 0.1 1.7 1 1 0 1 1 1 1 Fumarate reductase flavoprotein C-term NAD_binding_8 PF13450.6 RLN80475.1 - 0.012 15.8 0.1 0.033 14.4 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 RLN80475.1 - 0.017 14.4 0.1 4.8 6.4 0.0 3.1 3 0 0 3 3 3 0 Thi4 family FAD_binding_3 PF01494.19 RLN80475.1 - 0.017 14.4 0.1 0.029 13.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 RLN80475.1 - 0.082 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 RLN80475.1 - 0.11 12.2 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 RLN80475.1 - 0.42 9.2 2.8 3.1 6.4 0.3 2.7 3 0 0 3 3 3 0 HI0933-like protein FAD_oxidored PF12831.7 RLN80475.1 - 1.2 8.5 5.6 19 4.5 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Cellulase PF00150.18 RLN80476.1 - 2.1e-30 106.1 0.1 2.7e-30 105.8 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.25 RLN80478.1 - 2.3e-27 96.0 0.0 3.1e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN80478.1 - 7.5e-15 54.9 0.0 1e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAP30_Sin3_bdg PF13867.6 RLN80478.1 - 0.069 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 HTH_32 PF13565.6 RLN80479.1 - 3.8e-14 53.0 10.4 7e-07 29.8 0.3 3.7 3 0 0 3 3 3 2 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 RLN80479.1 - 4.1e-09 36.6 8.3 0.00038 20.6 0.6 4.2 4 0 0 4 4 4 2 Transposase HTH_23 PF13384.6 RLN80479.1 - 1.9e-08 33.9 3.5 9.3e-05 22.1 0.1 3.1 3 0 0 3 3 2 2 Homeodomain-like domain HTH_29 PF13551.6 RLN80479.1 - 1e-06 28.6 3.8 0.021 14.8 0.0 3.2 3 0 0 3 3 2 2 Winged helix-turn helix HTH_28 PF13518.6 RLN80479.1 - 1.9e-05 24.7 1.5 0.0016 18.5 0.2 3.0 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 RLN80479.1 - 2.1e-05 24.1 0.5 0.03 14.0 0.1 3.1 3 0 0 3 3 3 2 Sigma-70, region 4 HTH_38 PF13936.6 RLN80479.1 - 6e-05 22.7 2.3 0.026 14.3 0.0 3.3 3 0 0 3 3 3 2 Helix-turn-helix domain PAX PF00292.18 RLN80479.1 - 0.00019 21.3 4.9 0.07 13.1 0.3 2.5 2 0 0 2 2 2 2 'Paired box' domain HTH_Tnp_1 PF01527.20 RLN80479.1 - 0.00032 20.9 0.7 0.0024 18.2 0.2 2.9 2 0 0 2 2 2 1 Transposase RPA_C PF08784.11 RLN80479.1 - 0.0061 17.2 1.9 0.84 10.3 0.1 3.7 3 2 0 3 3 3 1 Replication protein A C terminal DUF4817 PF16087.5 RLN80479.1 - 0.011 15.6 0.9 15 5.5 0.0 3.9 3 1 0 3 3 3 0 Helix-turn-helix domain (DUF4817) HTH_12 PF08461.10 RLN80479.1 - 0.013 15.5 4.1 1.5 8.8 0.0 3.4 3 0 0 3 3 3 0 Ribonuclease R winged-helix domain Sigma70_r3 PF04539.16 RLN80479.1 - 0.016 15.3 0.0 0.27 11.4 0.0 2.9 2 0 0 2 2 2 0 Sigma-70 region 3 DUF3658 PF12395.8 RLN80479.1 - 0.022 14.6 0.0 6.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function HTH_DeoR PF08220.12 RLN80479.1 - 0.026 14.3 2.3 2 8.2 0.1 3.1 3 0 0 3 3 3 0 DeoR-like helix-turn-helix domain AT_hook PF02178.19 RLN80479.1 - 0.04 13.8 0.5 12 6.1 0.1 3.0 2 0 0 2 2 2 0 AT hook motif Ground-like PF04155.18 RLN80479.1 - 0.043 14.5 1.4 11 6.7 0.1 3.0 2 0 0 2 2 2 0 Ground-like domain HTH_Tnp_ISL3 PF13542.6 RLN80479.1 - 0.044 13.2 11.2 0.17 11.3 0.2 5.1 5 0 0 5 5 5 0 Helix-turn-helix domain of transposase family ISL3 DNA_meth_N PF18284.1 RLN80479.1 - 0.057 13.3 3.9 1.2 9.1 0.1 3.3 3 0 0 3 3 3 0 DNA methylase N-terminal domain MarR_2 PF12802.7 RLN80479.1 - 0.068 13.1 3.9 0.14 12.1 0.1 3.2 4 0 0 4 4 3 0 MarR family HTH_AsnC-type PF13404.6 RLN80479.1 - 0.077 12.8 7.9 21 5.0 0.0 5.5 5 1 0 5 5 5 0 AsnC-type helix-turn-helix domain Terminase_5 PF06056.12 RLN80479.1 - 0.14 12.1 0.0 24 4.9 0.0 2.6 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_24 PF13412.6 RLN80479.1 - 0.14 11.7 0.4 5.2 6.7 0.0 3.5 4 0 0 4 4 4 0 Winged helix-turn-helix DNA-binding CENP-B_N PF04218.13 RLN80479.1 - 0.15 11.7 2.1 10 5.8 0.0 3.5 4 0 0 4 4 4 0 CENP-B N-terminal DNA-binding domain Ank_2 PF12796.7 RLN80480.1 - 3.2e-36 123.8 12.1 5.4e-09 36.5 0.0 6.8 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN80480.1 - 5e-33 112.7 21.4 0.0037 17.5 0.0 14.5 6 2 10 16 16 16 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN80480.1 - 3.4e-31 107.2 10.5 0.00018 22.0 0.0 9.6 5 2 5 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN80480.1 - 1.2e-20 71.4 4.0 2.2 9.1 0.0 13.5 14 1 3 17 17 17 3 Ankyrin repeat DUF5049 PF16468.5 RLN80480.1 - 4.7e-06 26.4 0.0 43 4.1 0.0 7.2 5 2 3 8 8 8 0 Domain of unknown function (DUF5049) Ank PF00023.30 RLN80480.1 - 1e-05 25.7 1.3 1.1e+02 3.5 0.0 8.8 4 4 3 7 7 7 0 Ankyrin repeat Daxx PF03344.15 RLN80480.1 - 0.043 13.9 0.0 21 5.3 0.0 4.1 4 1 0 4 4 4 0 Daxx N-terminal Rassf1C-interacting domain RB_A PF01858.17 RLN80482.1 - 2.6e-59 200.4 0.0 4.4e-59 199.6 0.0 1.4 1 0 0 1 1 1 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 RLN80482.1 - 1.3e-30 106.2 0.0 2.6e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 RLN80482.1 - 2.6e-15 56.2 0.0 8.6e-15 54.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3452) Rb_C PF08934.10 RLN80482.1 - 0.00059 19.7 0.2 0.0018 18.1 0.2 1.9 1 0 0 1 1 1 1 Rb C-terminal domain AI-2E_transport PF01594.16 RLN80504.1 - 9.1e-28 97.3 15.7 9.1e-28 97.3 15.7 2.1 1 1 1 2 2 2 2 AI-2E family transporter RmlD_sub_bind PF04321.17 RLN80505.1 - 5.1e-09 35.6 0.0 6.7e-08 32.0 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 RLN80505.1 - 2.6e-07 30.7 0.0 3.8e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 RLN80505.1 - 2.4e-06 27.2 0.0 2.7e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 RLN80505.1 - 0.00023 20.3 0.0 0.079 11.9 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 RLN80505.1 - 0.0011 18.6 0.1 0.0028 17.3 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family DUF1640 PF07798.11 RLN80506.1 - 6.1e-08 32.9 4.9 1.4e-07 31.8 4.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) YppF PF14178.6 RLN80506.1 - 0.023 14.5 0.4 0.052 13.4 0.4 1.5 1 0 0 1 1 1 0 YppF-like protein DDE_Tnp_IS240 PF13610.6 RLN80506.1 - 0.033 14.4 0.1 0.048 13.9 0.1 1.3 1 1 0 1 1 1 0 DDE domain Enkurin PF13864.6 RLN80506.1 - 0.073 13.5 6.2 0.72 10.3 0.3 2.1 1 1 1 2 2 2 0 Calmodulin-binding PBECR3 PF18812.1 RLN80506.1 - 0.12 12.3 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 Wbp11 PF09429.10 RLN80506.1 - 2 8.8 7.6 19 5.7 7.6 2.0 1 1 0 1 1 1 0 WW domain binding protein 11 AAA_11 PF13086.6 RLN80507.1 - 1.8e-68 231.1 0.9 1.8e-68 231.1 0.9 3.2 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.6 RLN80507.1 - 6.1e-61 205.5 0.0 1.6e-60 204.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain Med26 PF08711.11 RLN80507.1 - 2.1e-12 46.9 1.9 2.1e-12 46.9 1.9 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain AAA_30 PF13604.6 RLN80507.1 - 3.4e-10 40.0 0.6 0.00011 21.9 0.1 2.9 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 RLN80507.1 - 6.2e-07 29.8 0.0 0.033 14.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 RLN80507.1 - 7.3e-05 22.6 0.0 0.16 11.7 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 RLN80507.1 - 0.065 13.2 0.1 0.73 9.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) PIN_4 PF13638.6 RLN80507.1 - 0.61 10.4 2.7 0.78 10.0 0.3 2.4 2 0 0 2 2 2 0 PIN domain DnaJ PF00226.31 RLN80508.1 - 5.2e-25 87.4 0.4 8.9e-25 86.6 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain zf-BED PF02892.15 RLN80510.1 - 0.0088 16.0 1.3 0.027 14.5 1.4 1.8 1 1 0 1 1 1 1 BED zinc finger GHMP_kinases_N PF00288.26 RLN80511.1 - 3.2e-14 52.9 3.9 6.8e-14 51.9 3.9 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 RLN80511.1 - 6.7e-05 23.2 0.1 6.7e-05 23.2 0.1 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal AA_permease_2 PF13520.6 RLN80512.1 - 1.2e-26 93.6 15.6 1.4e-26 93.4 15.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN80512.1 - 1.6e-16 60.0 14.4 1.8e-16 59.8 14.4 1.0 1 0 0 1 1 1 1 Amino acid permease Flavi_M PF01004.19 RLN80512.1 - 0.077 12.8 0.2 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M DUF2207 PF09972.9 RLN80512.1 - 1.1 7.9 3.6 5.6 5.6 0.7 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2244 PF10003.9 RLN80512.1 - 9 6.0 6.3 19 4.9 6.3 1.5 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Dimer_Tnp_hAT PF05699.14 RLN80537.1 - 2.7e-10 39.9 0.0 7.1e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4400 PF14348.6 RLN80538.1 - 1.3 8.4 9.6 0.39 10.2 5.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) PIN_12 PF16289.5 RLN80538.1 - 1.3 9.4 3.7 0.58 10.6 0.2 2.1 2 1 1 3 3 3 0 PIN domain Helitron_like_N PF14214.6 RLN80540.1 - 5.9e-11 42.9 0.1 5.9e-11 42.9 0.1 3.2 2 1 0 2 2 2 1 Helitron helicase-like domain at N-terminus TIP_N PF12457.8 RLN80563.1 - 0.055 13.9 0.3 0.055 13.9 0.3 2.2 2 0 0 2 2 2 0 Tuftelin interacting protein N terminal DUF1754 PF08555.10 RLN80563.1 - 2.4 9.0 8.4 0.69 10.7 5.4 1.7 2 1 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) PKD_channel PF08016.12 RLN80564.1 - 7.2e-30 104.0 7.8 9.7e-30 103.6 7.8 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 RLN80564.1 - 8.7e-09 35.0 9.2 1.7e-08 34.0 9.2 1.5 1 0 0 1 1 1 1 Ion transport protein Jiraiya PF15038.6 RLN80564.1 - 0.03 13.7 2.1 0.069 12.6 0.4 2.2 2 0 0 2 2 2 0 Jiraiya START PF01852.19 RLN80565.1 - 5.3e-20 71.7 0.0 8.2e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 START domain FYVE PF01363.21 RLN80565.1 - 6.1e-18 64.7 11.8 1.1e-17 63.9 11.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger Tir_receptor_C PF07489.11 RLN80565.1 - 0.0065 16.5 6.9 0.0065 16.5 6.9 2.1 2 0 0 2 2 2 1 Translocated intimin receptor (Tir) C-terminus FYVE_2 PF02318.16 RLN80565.1 - 0.017 15.4 5.3 0.031 14.5 5.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger IBR PF01485.21 RLN80565.1 - 0.053 13.8 4.0 0.12 12.6 4.0 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-CRD PF17979.1 RLN80565.1 - 1.4 9.0 9.3 6.2 6.9 9.3 2.0 1 1 0 1 1 1 0 Cysteine rich domain with multizinc binding regions Dicty_REP PF05086.12 RLN80565.1 - 5.2 4.9 4.7 7.2 4.5 4.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RCC1 PF00415.18 RLN80566.1 - 2.2e-73 242.7 22.9 4.2e-14 52.9 0.1 9.1 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN80566.1 - 1.3e-32 110.9 39.3 5.1e-09 35.7 0.6 7.6 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat SPRY PF00622.28 RLN80566.1 - 3.6e-15 56.1 0.0 8e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 SPRY domain Laminin_G_3 PF13385.6 RLN80566.1 - 1.8e-07 31.4 0.1 0.0014 18.8 0.0 3.7 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily PH PF00169.29 RLN80567.1 - 7.8e-07 29.6 0.0 0.049 14.1 0.0 2.6 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 RLN80567.1 - 0.0021 18.5 0.5 0.046 14.1 0.5 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain DUF4449 PF14613.6 RLN80567.1 - 0.0058 16.8 1.6 0.011 15.8 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) PH_8 PF15409.6 RLN80567.1 - 0.018 15.3 0.3 2.2 8.6 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain PH_13 PF16652.5 RLN80567.1 - 0.051 13.4 0.4 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain MFS_1 PF07690.16 RLN80568.1 - 2.1e-26 92.7 21.6 2.7e-26 92.3 21.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SPRY PF00622.28 RLN80569.1 - 7.4e-13 48.7 0.2 1.7e-12 47.5 0.2 1.6 1 0 0 1 1 1 1 SPRY domain HECT PF00632.25 RLN80569.1 - 5.7e-09 35.9 0.0 3.5e-05 23.4 0.0 3.0 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) Metallopep PF12044.8 RLN80570.1 - 2.6e-62 210.8 0.0 3.6e-62 210.4 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 RLN80570.1 - 2.4e-11 43.7 0.0 0.00019 21.3 0.0 3.4 3 0 0 3 3 3 2 Jacalin-like lectin domain Reprolysin_3 PF13582.6 RLN80570.1 - 0.017 15.6 0.3 0.033 14.7 0.3 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RLN80570.1 - 0.032 13.9 0.1 0.066 12.8 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 RLN80570.1 - 0.046 13.6 0.1 0.086 12.7 0.1 1.4 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 RLN80570.1 - 0.052 12.5 0.6 0.091 11.7 0.6 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M54 PF07998.11 RLN80570.1 - 0.066 13.2 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin_5 PF13688.6 RLN80570.1 - 0.096 12.8 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Nup84_Nup100 PF04121.13 RLN80571.1 - 3.3e-154 514.8 13.5 4.1e-154 514.5 13.5 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 HMMR_C PF15908.5 RLN80571.1 - 0.0054 17.0 1.7 0.011 16.1 0.6 2.1 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor C-terminal Patatin PF01734.22 RLN80572.1 - 1.2e-11 45.2 0.1 9.1e-10 39.0 0.1 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase PH PF00169.29 RLN80573.1 - 2e-06 28.2 0.0 3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN80573.1 - 0.077 13.4 0.0 0.21 12.0 0.0 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain PGBA_C PF15437.6 RLN80574.1 - 0.071 13.5 3.3 0.18 12.2 3.3 1.6 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal Na_Ca_ex PF01699.24 RLN80575.1 - 3.2e-37 127.8 32.7 2e-21 76.5 8.9 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein CobU PF02283.16 RLN80575.1 - 0.013 15.1 1.4 0.022 14.3 1.4 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF1115 PF06544.12 RLN80575.1 - 0.38 10.8 1.8 0.63 10.1 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) Nop53 PF07767.11 RLN80576.1 - 1.7e-26 93.6 24.9 1.9e-16 60.5 10.8 2.6 2 1 1 3 3 3 2 Nop53 (60S ribosomal biogenesis) DUF2207 PF09972.9 RLN80576.1 - 0.045 12.5 0.1 0.065 12.0 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3671 PF12420.8 RLN80576.1 - 4.2 7.5 6.1 1.8 8.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function AATF-Che1 PF13339.6 RLN80577.1 - 0.17 12.5 2.8 0.43 11.3 2.8 1.6 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF948 PF06103.11 RLN80577.1 - 0.89 9.9 4.1 10 6.5 0.2 3.6 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) GAS PF13851.6 RLN80577.1 - 2.3 7.5 9.7 0.086 12.2 1.1 2.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding tRNA-synt_1d PF00750.19 RLN80578.1 - 2.3e-117 391.9 0.2 4e-117 391.1 0.1 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (R) DALR_1 PF05746.15 RLN80578.1 - 3.5e-22 78.8 0.0 8.6e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 RLN80578.1 - 7.3e-17 61.7 0.0 1.8e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 RLN80578.1 - 0.00046 19.6 0.1 0.0009 18.7 0.1 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.22 RLN80578.1 - 0.0018 16.6 0.1 0.0027 16.0 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 RLN80578.1 - 0.033 13.0 0.0 0.052 12.3 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (M) GST_C_2 PF13410.6 RLN80578.1 - 0.035 14.1 0.0 0.23 11.5 0.0 2.4 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RLN80578.1 - 0.054 13.7 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RWP-RK PF02042.15 RLN80579.1 - 7.7e-19 67.4 0.1 1.3e-18 66.6 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_6 PF01418.17 RLN80579.1 - 0.11 12.4 0.1 0.32 11.0 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Na_Pi_cotrans PF02690.15 RLN80580.1 - 1.2e-33 116.2 36.5 4.4e-20 72.2 9.0 3.5 3 1 1 4 4 4 2 Na+/Pi-cotransporter Palm_thioest PF02089.15 RLN80581.1 - 1e-42 146.6 0.2 5.1e-41 141.1 0.0 2.4 2 0 0 2 2 2 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 RLN80581.1 - 0.00033 20.4 0.6 0.0028 17.3 0.1 2.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 RLN80581.1 - 0.083 12.4 2.0 0.098 12.2 0.2 2.0 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DUF676 PF05057.14 RLN80581.1 - 0.12 11.8 0.0 0.36 10.3 0.0 1.8 1 0 0 1 1 1 0 Putative serine esterase (DUF676) RolB_RolC PF02027.17 RLN80581.1 - 2.4 7.8 4.4 14 5.3 0.4 2.5 2 0 0 2 2 2 0 RolB/RolC glucosidase family CLU PF13236.6 RLN80582.1 - 2.7e-41 141.8 0.0 6.3e-41 140.6 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria LRR_6 PF13516.6 RLN80582.1 - 3.2e-16 57.9 16.7 0.0054 16.7 0.0 12.0 12 0 0 12 12 12 4 Leucine Rich repeat Laminin_G_3 PF13385.6 RLN80582.1 - 8.5e-13 48.7 0.0 1.2e-10 41.8 0.0 2.5 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily eIF3_p135 PF12807.7 RLN80582.1 - 4.8e-08 33.2 0.1 4.6e-07 30.0 0.0 2.8 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 LRR_4 PF12799.7 RLN80582.1 - 8.5e-05 22.8 11.7 18 5.9 0.1 7.5 6 2 2 8 8 8 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN80582.1 - 0.022 15.2 18.3 32 5.6 0.0 8.4 8 1 0 8 8 8 0 Leucine Rich Repeat ASF1_hist_chap PF04729.13 RLN80583.1 - 0.2 11.6 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 ASF1 like histone chaperone His_Phos_1 PF00300.22 RLN80584.1 - 1.5e-08 34.6 0.0 8.8e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Trypsin_2 PF13365.6 RLN80585.1 - 8.5e-19 68.9 0.2 2.4e-18 67.5 0.2 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain CUB PF00431.20 RLN80585.1 - 0.13 12.6 0.0 0.39 11.1 0.0 1.8 1 0 0 1 1 1 0 CUB domain Peptidase_S46 PF10459.9 RLN80585.1 - 0.16 10.6 3.0 1 7.9 0.4 2.1 2 0 0 2 2 2 0 Peptidase S46 Trypsin_2 PF13365.6 RLN80586.1 - 9.2e-19 68.8 0.1 5.9e-18 66.2 0.0 2.1 2 1 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 RLN80586.1 - 0.00052 19.9 1.1 0.0026 17.6 1.1 2.2 1 1 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 RLN80586.1 - 0.0033 16.2 2.1 0.057 12.1 0.7 2.1 2 0 0 2 2 2 2 Peptidase S46 MIP PF00230.20 RLN80613.1 - 2.7e-55 187.5 4.9 3.5e-55 187.2 4.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein IQ PF00612.27 RLN80635.1 - 1e-16 59.1 53.7 0.0012 18.5 0.4 9.2 9 0 0 9 9 9 7 IQ calmodulin-binding motif zf-B_box PF00643.24 RLN80635.1 - 5.6e-07 29.6 18.3 0.0013 18.9 2.8 2.4 2 0 0 2 2 2 2 B-box zinc finger WW PF00397.26 RLN80635.1 - 2.9e-05 24.0 13.3 0.00011 22.2 1.3 2.6 2 0 0 2 2 2 2 WW domain CEBP_ZZ PF16366.5 RLN80635.1 - 0.011 16.0 21.1 0.5 10.6 8.4 2.6 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain ArfGap PF01412.18 RLN80635.1 - 4.9 7.3 20.0 2 8.5 6.7 2.9 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf EphA2_TM PF14575.6 RLN80636.1 - 0.017 16.0 0.0 0.44 11.5 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain ACP_syn_III PF08545.10 RLN80636.1 - 0.14 12.0 0.3 9 6.2 0.1 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF1206 PF06724.11 RLN80670.1 - 0.05 13.7 0.5 0.73 10.0 0.5 2.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) RRM_1 PF00076.22 RLN80671.1 - 4.1e-79 260.4 3.3 9.9e-22 76.5 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RLN80671.1 - 2.3e-10 40.2 0.0 0.024 14.3 0.0 4.6 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 RLN80671.1 - 1.9e-07 31.0 0.1 0.84 9.7 0.0 4.8 5 0 0 5 5 5 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 RLN80671.1 - 2.6e-07 30.4 0.0 0.018 14.9 0.0 3.9 4 0 0 4 4 4 2 Occluded RNA-recognition motif PHM7_cyt PF14703.6 RLN80671.1 - 0.00019 21.7 1.4 1.8 8.8 0.0 5.3 3 2 2 5 5 5 1 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 RLN80671.1 - 0.0064 16.6 0.0 12 6.1 0.0 3.9 4 0 0 4 4 4 1 RNA recognition motif RRM_3 PF08777.11 RLN80671.1 - 0.022 14.8 0.0 19 5.4 0.0 4.1 4 0 0 4 4 4 0 RNA binding motif Transgly PF00912.22 RLN80671.1 - 0.075 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Transglycosylase SET_assoc PF11767.8 RLN80671.1 - 0.18 11.5 0.0 2.5 7.8 0.0 2.7 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Helicase_C PF00271.31 RLN80672.1 - 1.4e-25 89.8 0.0 2.9e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RLN80672.1 - 2e-14 53.8 0.9 1.5e-13 50.9 0.9 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase CDC45 PF02724.14 RLN80672.1 - 0.0082 14.5 5.1 0.012 13.9 5.1 1.2 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 RLN80672.1 - 0.014 13.6 10.0 0.025 12.8 10.0 1.3 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 RLN80672.1 - 0.19 11.8 13.3 0.013 15.6 8.1 1.7 2 0 0 2 2 2 0 YL1 nuclear protein NOA36 PF06524.12 RLN80672.1 - 0.19 11.0 8.9 0.32 10.3 8.9 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 RLN80672.1 - 0.21 9.6 17.4 0.35 8.9 17.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 RLN80672.1 - 0.42 9.1 8.0 0.69 8.4 8.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4743 PF15916.5 RLN80674.1 - 6.2e-14 52.0 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 RLN80674.1 - 3.4e-06 27.1 0.0 7.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DUF1206 PF06724.11 RLN80675.1 - 0.035 14.2 0.7 0.4 10.8 0.8 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) Aldedh PF00171.22 RLN80676.1 - 1.1e-13 50.5 4.5 2.3e-09 36.3 1.9 2.6 2 1 0 2 2 2 2 Aldehyde dehydrogenase family AA_kinase PF00696.28 RLN80676.1 - 4.9e-07 29.6 0.0 1.1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family Acyl-CoA_ox_N PF14749.6 RLN80677.1 - 9.6e-20 71.4 0.0 1.3e-19 71.0 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Pre-PUA PF17832.1 RLN80677.1 - 0.13 12.9 0.0 0.28 11.9 0.0 1.5 1 1 0 1 1 1 0 Pre-PUA-like domain DNA_alkylation PF08713.11 RLN80678.1 - 0.093 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 DNA alkylation repair enzyme HLH PF00010.26 RLN80679.1 - 0.0035 17.3 5.3 0.0092 15.9 5.3 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain TSC22 PF01166.18 RLN80679.1 - 0.02 15.2 3.9 0.87 9.9 0.1 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family FAM76 PF16046.5 RLN80679.1 - 0.022 14.1 3.4 0.031 13.6 3.4 1.1 1 0 0 1 1 1 0 FAM76 protein Vir_act_alpha_C PF10400.9 RLN80679.1 - 0.27 11.9 0.1 0.27 11.9 0.1 2.4 2 0 0 2 2 2 0 Virulence activator alpha C-term ATG16 PF08614.11 RLN80679.1 - 0.56 10.4 14.3 1.6 8.9 14.1 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) NYD-SP28_assoc PF14775.6 RLN80679.1 - 3.8 7.7 8.2 0.92 9.7 0.5 2.5 2 0 0 2 2 2 0 Sperm tail C-terminal domain Elicitin PF00964.17 RLN80680.1 - 3.9e-12 46.1 0.5 6.2e-12 45.5 0.5 1.4 1 0 0 1 1 1 1 Elicitin Period_C PF12114.8 RLN80680.1 - 5.4 6.6 8.9 8.8 5.9 8.9 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region FYVE_2 PF02318.16 RLN80681.1 - 0.21 11.8 7.8 0.58 10.4 7.8 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4_2 PF13923.6 RLN80681.1 - 0.22 11.4 7.9 1.5 8.7 3.8 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN80681.1 - 1.1 9.1 10.3 0.84 9.6 4.2 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN80681.1 - 1.3 9.4 9.7 2.5 8.5 4.0 2.5 1 1 1 2 2 2 0 Ring finger domain FYVE PF01363.21 RLN80681.1 - 5.9 7.1 14.2 20 5.4 14.2 1.9 1 0 0 1 1 1 0 FYVE zinc finger Elicitin PF00964.17 RLN80682.1 - 1.3e-07 31.6 0.1 2e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Elicitin CS PF04969.16 RLN80707.1 - 0.01 16.8 0.0 0.02 15.9 0.0 1.5 1 0 0 1 1 1 0 CS domain CTP_transf_3 PF02348.19 RLN80710.1 - 1.3e-48 165.8 0.0 1.6e-48 165.5 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 RLN80710.1 - 3.3e-06 27.6 0.0 6.1e-06 26.7 0.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 RLN80710.1 - 0.0054 16.5 0.0 0.0081 15.9 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase FLYWCH_N PF15423.6 RLN80710.1 - 0.031 14.4 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 FLYWCH-type zinc finger-containing protein Metallophos PF00149.28 RLN80711.1 - 3.5e-14 53.8 0.0 5.4e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Suc_Fer-like PF06999.12 RLN80711.1 - 0.043 13.7 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Sucrase/ferredoxin-like LRR_6 PF13516.6 RLN80713.1 - 0.075 13.1 0.4 4 7.7 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeat MutL_C PF08676.11 RLN80714.1 - 1.1e-08 35.0 0.0 1.4e-07 31.3 0.0 2.2 1 1 0 1 1 1 1 MutL C terminal dimerisation domain SAM_1 PF00536.30 RLN80715.1 - 1.2e-06 28.8 0.7 3.5e-05 24.1 0.0 2.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RLN80715.1 - 2.5e-06 27.5 7.4 2.4e-05 24.3 0.2 3.4 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) T6PP_N PF18572.1 RLN80715.1 - 0.44 10.4 4.6 0.34 10.8 0.6 2.5 1 1 1 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain RNase_H2_suC PF08615.11 RLN80715.1 - 0.7 10.1 10.5 2.4 8.3 4.9 2.9 2 1 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Baculo_PEP_C PF04513.12 RLN80715.1 - 7.5 6.6 13.0 2.3 8.3 5.5 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-B_dimeris PF09026.10 RLN80715.1 - 8.2 6.9 37.1 4.2 7.8 12.8 3.6 4 0 0 4 4 4 0 Centromere protein B dimerisation domain Syja_N PF02383.18 RLN80716.1 - 8.9e-75 252.0 0.0 6.9e-74 249.0 0.0 2.2 2 0 0 2 2 2 1 SacI homology domain Pkinase PF00069.25 RLN80717.1 - 1.5e-37 129.4 0.0 1.3e-36 126.4 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN80717.1 - 1.7e-30 106.2 0.0 3.3e-21 75.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DEP PF00610.21 RLN80717.1 - 1.1e-05 25.4 0.0 2.8e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) APH PF01636.23 RLN80717.1 - 0.0013 18.8 0.4 0.0033 17.4 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family RAI1 PF08652.11 RLN80718.1 - 2.6e-19 69.2 0.2 6e-19 68.0 0.2 1.7 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease EGF_2 PF07974.13 RLN80718.1 - 6.6e-07 29.6 48.6 0.0015 18.8 12.3 4.8 4 0 0 4 4 4 3 EGF-like domain EGF PF00008.27 RLN80718.1 - 0.001 19.3 3.6 0.001 19.3 3.6 4.9 4 0 0 4 4 4 1 EGF-like domain hEGF PF12661.7 RLN80718.1 - 0.0026 18.4 3.3 0.0026 18.4 3.3 6.4 5 1 0 5 5 5 2 Human growth factor-like EGF DUF2142 PF09913.9 RLN80718.1 - 0.1 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) Laminin_EGF PF00053.24 RLN80718.1 - 0.55 10.4 47.1 0.06 13.5 14.2 4.3 2 1 2 4 4 4 0 Laminin EGF domain Pkinase PF00069.25 RLN80719.1 - 1.1e-39 136.5 0.0 8.7e-39 133.5 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN80719.1 - 8.9e-37 126.8 0.0 6.7e-24 84.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DEP PF00610.21 RLN80719.1 - 9e-06 25.7 0.0 2.1e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) APH PF01636.23 RLN80719.1 - 0.011 15.7 0.2 0.038 13.9 0.2 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family PsbI PF02532.14 RLN80720.1 - 0.4 10.7 1.8 0.77 9.7 1.8 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Golgin_A5 PF09787.9 RLN80752.1 - 1.5e-20 73.9 43.0 5e-20 72.2 8.9 2.6 1 1 1 2 2 2 2 Golgin subfamily A member 5 CASP_C PF08172.12 RLN80752.1 - 2.1e-05 24.0 1.2 2.1e-05 24.0 1.2 5.0 2 1 3 5 5 5 1 CASP C terminal TMF_DNA_bd PF12329.8 RLN80752.1 - 0.0095 15.9 8.7 0.0095 15.9 8.7 6.0 3 2 1 5 5 5 3 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 RLN80752.1 - 1.2 9.2 41.0 0.019 15.1 10.3 3.2 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 RLN80752.1 - 1.5 9.0 38.0 0.04 14.1 11.0 4.1 2 1 3 5 5 5 0 Fibrinogen alpha/beta chain family ATG16 PF08614.11 RLN80752.1 - 1.8 8.7 59.4 22 5.2 8.0 4.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 RLN80752.1 - 3.4 8.1 47.2 8 6.9 23.2 3.4 1 1 1 2 2 2 0 Fez1 PKcGMP_CC PF16808.5 RLN80752.1 - 7 6.6 7.6 7.8 6.4 1.0 3.5 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SET PF00856.28 RLN80753.1 - 6.8e-13 49.3 4.6 1.7e-12 48.1 0.0 3.6 2 2 0 2 2 2 1 SET domain preSET_CXC PF18264.1 RLN80753.1 - 7.4e-09 35.9 15.2 7.4e-09 35.9 15.2 3.4 2 1 1 3 3 3 1 CXC domain TCR PF03638.15 RLN80753.1 - 1.6 9.1 32.9 1.6 9.1 11.9 2.7 2 0 0 2 2 2 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain ELMO_CED12 PF04727.13 RLN80754.1 - 1.1e-36 126.6 0.0 2e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family RUN PF02759.19 RLN80754.1 - 8.4e-17 61.4 0.0 2.7e-16 59.7 0.0 1.9 1 0 0 1 1 1 1 RUN domain RhoGAP PF00620.27 RLN80754.1 - 8.1e-15 55.0 0.0 1.7e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FRG PF08867.11 RLN80755.1 - 0.093 13.7 0.4 0.24 12.4 0.4 1.8 1 1 0 1 1 1 0 FRG domain zf-C2HC5 PF06221.13 RLN80756.1 - 0.0014 18.5 0.2 0.0034 17.4 0.2 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type STG PF15809.5 RLN80757.1 - 0.12 12.5 2.1 0.13 12.3 1.2 1.5 1 1 0 1 1 1 0 Simian taste bud-specific gene product family MinC_C PF03775.16 RLN80793.1 - 2.2e-29 101.5 0.1 4.2e-29 100.5 0.1 1.5 1 0 0 1 1 1 1 Septum formation inhibitor MinC, C-terminal domain FapA PF03961.13 RLN80793.1 - 0.023 13.3 0.3 0.037 12.6 0.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A COPIIcoated_ERV PF07970.12 RLN80794.1 - 1e-32 113.8 0.1 2e-32 112.8 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Thioredoxin PF00085.20 RLN80794.1 - 1.7e-21 76.1 0.1 4.3e-21 74.8 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin ERGIC_N PF13850.6 RLN80794.1 - 4.3e-15 55.8 0.2 9.6e-15 54.7 0.2 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin_2 PF13098.6 RLN80794.1 - 0.0024 18.3 0.1 0.0071 16.8 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RLN80794.1 - 0.034 14.5 1.7 0.29 11.5 0.0 2.7 3 0 0 3 3 3 0 Thioredoxin-like OST3_OST6 PF04756.13 RLN80794.1 - 0.093 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family TPR_1 PF00515.28 RLN80795.1 - 3.4e-12 45.6 4.2 0.00053 19.7 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN80795.1 - 2.7e-11 42.7 6.7 0.011 15.8 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN80795.1 - 7.7e-07 28.7 4.5 0.0011 18.6 0.3 2.8 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 RLN80795.1 - 0.00035 21.2 10.5 0.0015 19.1 1.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN80795.1 - 0.00045 20.4 0.3 0.014 15.7 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat CHASE7 PF17151.4 RLN80795.1 - 0.00066 19.3 0.6 0.0013 18.4 0.6 1.4 1 0 0 1 1 1 1 Periplasmic sensor domain TPR_9 PF13371.6 RLN80795.1 - 0.0047 17.0 10.1 0.0071 16.5 2.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN80795.1 - 0.0091 16.5 2.3 0.0091 16.5 2.3 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN80795.1 - 0.011 15.9 1.4 1.2 9.6 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN80795.1 - 0.038 14.2 5.1 0.25 11.6 0.2 3.1 1 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 POPLD PF08170.12 RLN80795.1 - 0.11 12.8 2.1 5 7.5 0.6 2.4 2 0 0 2 2 2 0 POPLD (NUC188) domain TPR_14 PF13428.6 RLN80795.1 - 1.5 9.8 11.1 0.8 10.7 1.3 4.1 2 1 2 4 4 4 0 Tetratricopeptide repeat SRP40_C PF05022.12 RLN80800.1 - 1.7e-22 80.1 0.6 1.7e-22 80.1 0.6 2.6 2 0 0 2 2 2 1 SRP40, C-terminal domain LisH PF08513.11 RLN80800.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 LisH Ribosomal_L27 PF01016.19 RLN80830.1 - 2.6e-35 120.3 3.0 3.1e-35 120.0 3.0 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein PK PF00224.21 RLN80831.1 - 2.1e-100 336.0 1.1 1.9e-96 323.0 1.1 2.2 2 0 0 2 2 2 2 Pyruvate kinase, barrel domain PK_C PF02887.16 RLN80831.1 - 5.7e-21 74.9 1.5 1.9e-20 73.2 1.4 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 RLN80831.1 - 0.0001 21.6 0.6 0.00023 20.4 0.2 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Methyltr_RsmF_N PF17125.5 RLN80832.1 - 1.3e-08 35.2 0.0 4.7e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltr_RsmB-F PF01189.17 RLN80832.1 - 1.5e-08 34.6 0.0 2.6e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F CDC27 PF09507.10 RLN80832.1 - 0.023 14.1 25.3 0.031 13.7 25.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SDA1 PF05285.12 RLN80832.1 - 2.3 7.6 38.2 3.2 7.1 38.2 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RLN80832.1 - 3.4 5.8 33.7 4.2 5.4 33.7 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 RLN80832.1 - 3.5 6.1 34.5 4.4 5.8 34.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) eIF-3c_N PF05470.12 RLN80832.1 - 3.8 5.7 15.5 5.4 5.2 15.5 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SMC_N PF02463.19 RLN80833.1 - 4.2e-20 72.1 0.0 5.6e-13 48.8 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RLN80833.1 - 6.8e-10 39.8 41.8 4.3e-07 30.6 30.6 4.5 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 RLN80833.1 - 3.1e-05 23.8 1.2 3.1e-05 23.8 1.2 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 RLN80833.1 - 0.00036 20.2 0.0 0.00072 19.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN80833.1 - 0.0072 15.9 0.2 0.25 10.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 RLN80833.1 - 0.031 14.1 1.6 0.17 11.7 0.2 2.6 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 RLN80833.1 - 0.062 13.0 0.3 6 6.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 RLN80833.1 - 0.063 13.7 0.4 1.3 9.4 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 RLN80833.1 - 0.34 10.7 18.1 0.44 10.3 9.8 3.2 2 1 0 2 2 2 0 AAA domain KxDL PF10241.9 RLN80833.1 - 0.73 10.2 12.7 4.6 7.6 3.2 3.9 3 1 0 3 3 3 0 Uncharacterized conserved protein AIF-MLS PF14962.6 RLN80833.1 - 1.4 8.8 6.9 4 7.4 6.9 1.7 1 0 0 1 1 1 0 Mitochondria Localisation Sequence FlaC_arch PF05377.11 RLN80833.1 - 1.5 9.3 16.0 14 6.1 0.6 5.7 6 0 0 6 6 5 0 Flagella accessory protein C (FlaC) ABC_tran PF00005.27 RLN80833.1 - 4.6 7.7 9.4 6.7 7.2 5.4 3.4 2 2 0 2 2 2 0 ABC transporter ANTH PF07651.16 RLN80834.1 - 0.068 12.1 0.0 0.22 10.5 0.0 1.7 2 0 0 2 2 2 0 ANTH domain Cnd1 PF12717.7 RLN80834.1 - 0.075 13.1 0.1 9.7 6.2 0.1 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 CYSTM PF12734.7 RLN80834.1 - 0.32 11.3 18.2 0.39 11.1 2.9 4.0 3 0 0 3 3 3 0 Cysteine-rich TM module stress tolerance SET PF00856.28 RLN80835.1 - 0.00043 20.7 0.0 0.0025 18.2 0.0 2.2 1 1 0 1 1 1 1 SET domain SATase_N PF06426.14 RLN80835.1 - 0.084 13.3 0.1 0.29 11.5 0.1 2.0 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal CDKN3 PF05706.12 RLN80835.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Lactamase_B_4 PF13691.6 RLN80836.1 - 0.0014 18.3 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 RLN80836.1 - 0.031 13.8 0.0 0.06 12.8 0.0 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain PDEase_II PF02112.15 RLN80836.1 - 0.24 10.5 1.7 0.35 9.9 0.7 1.7 1 1 1 2 2 2 0 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 RLN80836.1 - 0.25 11.3 1.7 0.46 10.5 1.7 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily LRAT PF04970.13 RLN80837.1 - 5.7e-20 71.9 0.0 1.6e-19 70.5 0.0 1.7 1 1 0 1 1 1 1 Lecithin retinol acyltransferase Romo1 PF10247.9 RLN80837.1 - 0.0034 17.7 4.3 0.0068 16.7 4.3 1.5 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Rick_17kDa_Anti PF05433.15 RLN80837.1 - 0.016 15.0 13.8 0.044 13.7 13.8 1.8 1 0 0 1 1 1 0 Glycine zipper 2TM domain NLPC_P60 PF00877.19 RLN80837.1 - 0.021 14.9 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 NlpC/P60 family Gly-zipper_YMGG PF13441.6 RLN80837.1 - 0.3 10.8 16.3 1.3 8.9 16.3 2.0 1 1 0 1 1 1 0 YMGG-like Gly-zipper ABC_tran PF00005.27 RLN80838.1 - 9.1e-21 74.8 0.0 1.3e-20 74.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter IstB_IS21 PF01695.17 RLN80838.1 - 2.9e-05 23.9 0.1 0.14 11.9 0.0 2.2 2 0 0 2 2 2 2 IstB-like ATP binding protein SMC_N PF02463.19 RLN80838.1 - 2.9e-05 23.6 0.3 0.033 13.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RLN80838.1 - 0.00019 21.4 0.3 0.27 11.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 RLN80838.1 - 0.014 15.4 0.6 0.037 14.1 0.1 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 RLN80838.1 - 0.016 15.5 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 RLN80838.1 - 0.021 14.9 0.3 0.035 14.2 0.3 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain Dynamin_N PF00350.23 RLN80838.1 - 0.022 14.8 0.1 0.035 14.2 0.1 1.3 1 0 0 1 1 1 0 Dynamin family AAA_5 PF07728.14 RLN80838.1 - 0.15 12.0 0.3 10 6.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RLN80838.1 - 0.2 12.0 2.0 0.6 10.5 1.9 1.9 1 1 0 1 1 1 0 AAA ATPase domain C12orf66_like PF09404.10 RLN80839.1 - 8.3e-18 64.4 4.2 3.1e-08 32.9 0.1 3.1 3 0 0 3 3 3 3 KICSTOR complex C12orf66 like Microtub_bind PF13931.6 RLN80839.1 - 0.33 11.3 4.4 13 6.2 0.0 2.7 3 0 0 3 3 3 0 Kinesin-associated microtubule-binding YcbB PF08664.10 RLN80840.1 - 0.0087 16.1 0.3 0.015 15.4 0.0 1.6 2 0 0 2 2 2 1 YcbB domain Fez1 PF06818.15 RLN80841.1 - 0.92 9.9 38.1 4 7.8 6.2 2.8 2 1 0 2 2 2 0 Fez1 dCache_1 PF02743.18 RLN80841.1 - 1.1 9.0 3.6 2.1 8.1 3.6 1.4 1 0 0 1 1 1 0 Cache domain CLTH PF10607.9 RLN80842.1 - 4.2e-28 98.1 0.1 1.4e-27 96.4 0.0 1.8 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain DUF1682 PF07946.14 RLN80842.1 - 7.9e-19 68.0 0.2 7.9e-19 68.0 0.2 3.7 2 1 2 4 4 4 3 Protein of unknown function (DUF1682) Med21 PF11221.8 RLN80842.1 - 0.28 11.4 4.1 0.7 10.1 4.1 1.7 1 0 0 1 1 1 0 Subunit 21 of Mediator complex HTH_Tnp_Tc5 PF03221.16 RLN80844.1 - 1e-09 38.3 1.1 3.1e-09 36.7 0.1 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Utp14 PF04615.13 RLN80844.1 - 0.0027 16.4 7.8 0.0027 16.4 7.8 2.4 2 0 0 2 2 2 1 Utp14 protein HTH_24 PF13412.6 RLN80844.1 - 0.029 13.9 0.0 0.067 12.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding AIM3 PF17096.5 RLN80844.1 - 9.1 7.3 17.1 0.45 11.5 5.6 2.9 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 Myb_DNA-bind_6 PF13921.6 RLN80863.1 - 0.034 14.4 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain IF-2B PF01008.17 RLN80864.1 - 3.2e-52 177.5 0.8 5.9e-52 176.6 0.8 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family cNMP_binding PF00027.29 RLN80865.1 - 2.3e-40 136.6 3.3 2.1e-17 62.9 0.2 3.3 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain RPN13_C PF16550.5 RLN80865.1 - 0.06 13.5 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 UCH-binding domain GvpL_GvpF PF06386.11 RLN80887.1 - 0.057 13.4 5.9 0.067 13.1 5.9 1.0 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF BNIP2 PF12496.8 RLN80887.1 - 0.12 12.8 1.2 0.5 10.8 1.4 1.7 1 1 1 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 SET PF00856.28 RLN80888.1 - 0.027 14.9 0.8 1.6 9.1 0.0 2.9 2 1 0 2 2 2 0 SET domain IBN_N PF03810.19 RLN80911.1 - 8.1e-10 38.5 0.4 4.7e-08 32.8 0.0 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain Antimicrobial21 PF14861.6 RLN80911.1 - 1.6 8.5 5.6 3.2 7.5 5.6 1.5 1 0 0 1 1 1 0 Plant antimicrobial peptide Arrestin_C PF02752.22 RLN80913.1 - 2e-10 41.2 0.0 3.3e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Aldo_ket_red PF00248.21 RLN80915.1 - 7.8e-55 186.1 0.0 1.2e-54 185.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Erf4 PF10256.9 RLN80915.1 - 0.011 15.9 0.0 0.045 13.9 0.0 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family Ephrin_rec_like PF07699.13 RLN80915.1 - 0.015 15.0 0.3 0.042 13.6 0.3 1.7 1 0 0 1 1 1 0 Putative ephrin-receptor like DIM1 PF02966.16 RLN80916.1 - 1.1e-65 219.4 0.1 1.3e-65 219.2 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 RLN80916.1 - 0.0039 17.2 0.0 0.0054 16.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin NDK PF00334.19 RLN80917.1 - 7.1e-38 129.7 0.0 2e-23 82.9 0.0 2.1 2 0 0 2 2 2 2 Nucleoside diphosphate kinase PNRC PF15365.6 RLN80918.1 - 5.5e-07 29.2 3.1 2.9e-06 26.9 3.1 2.4 1 0 0 1 1 1 1 Proline-rich nuclear receptor coactivator motif Presenilin PF01080.17 RLN80918.1 - 3.5 6.3 5.2 4.6 5.9 5.2 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 RLN80918.1 - 5.5 5.4 8.7 6.7 5.1 8.7 1.0 1 0 0 1 1 1 0 Macoilin family zf-RING_2 PF13639.6 RLN80919.1 - 1.3e-09 38.2 6.2 1.3e-09 38.2 6.2 4.5 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN80919.1 - 3.7e-08 33.1 4.7 3.7e-08 33.1 4.7 4.1 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN80919.1 - 1.4e-07 31.7 3.9 1.4e-07 31.7 3.9 3.3 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 RLN80919.1 - 5.2e-07 29.4 2.2 5.2e-07 29.4 2.2 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) TCR PF03638.15 RLN80919.1 - 0.015 15.6 15.8 0.015 15.6 15.8 3.5 2 1 0 2 2 2 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain zf-RING_11 PF17123.5 RLN80919.1 - 0.021 14.6 4.8 0.021 14.6 4.8 3.1 2 1 0 2 2 2 0 RING-like zinc finger Atg14 PF10186.9 RLN80923.1 - 0.25 10.4 8.3 0.37 9.8 8.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 RLN80925.1 - 1 8.6 9.5 1.7 8.0 9.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Ephrin PF00812.17 RLN80926.1 - 0.088 12.8 0.3 0.23 11.5 0.3 1.7 1 1 0 1 1 1 0 Ephrin AbiTii PF18864.1 RLN80926.1 - 0.13 12.4 0.2 0.28 11.3 0.2 1.6 1 1 1 2 2 2 0 AbiTii Nmad3 PF18754.1 RLN80926.1 - 0.15 11.6 0.4 0.26 10.8 0.4 1.4 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 DUF725 PF05267.12 RLN80926.1 - 1.1 9.3 4.8 0.27 11.2 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF725) DUF4407 PF14362.6 RLN80927.1 - 7.3 5.9 9.3 11 5.3 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4452 PF14618.6 RLN80927.1 - 8.4 6.2 9.5 0.91 9.4 3.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4452) ABC_tran_CTD PF16326.5 RLN80929.1 - 0.048 13.9 0.7 0.14 12.4 0.7 1.8 1 0 0 1 1 1 0 ABC transporter C-terminal domain MORN PF02493.20 RLN80930.1 - 1.8e-41 137.6 42.5 7.3e-07 28.7 0.9 8.3 8 0 0 8 8 8 8 MORN repeat Aldo_ket_red PF00248.21 RLN80931.1 - 2e-62 211.1 0.0 2.2e-62 210.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hus1 PF04005.12 RLN80931.1 - 0.039 13.1 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Hus1-like protein DUF2777 PF10949.8 RLN80931.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) PAH PF02671.21 RLN80932.1 - 3.7e-26 91.0 8.9 3.2e-13 49.6 0.4 2.7 2 0 0 2 2 2 2 Paired amphipathic helix repeat CCM2_C PF16545.5 RLN80932.1 - 0.0014 19.1 0.1 0.092 13.3 0.1 2.3 2 0 0 2 2 2 1 Cerebral cavernous malformation protein, harmonin-homology IL5 PF02025.15 RLN80932.1 - 0.017 15.4 0.0 0.46 10.8 0.0 2.4 2 0 0 2 2 2 0 Interleukin 5 Ku_PK_bind PF08785.11 RLN80932.1 - 0.038 14.1 1.2 4.4 7.5 0.0 2.7 3 0 0 3 3 3 0 Ku C terminal domain like MDD_C PF18376.1 RLN80932.1 - 0.057 13.1 0.1 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain Peptidase_C50 PF03568.17 RLN80962.1 - 3e-33 115.5 0.5 6.4e-33 114.4 0.2 1.7 2 0 0 2 2 2 1 Peptidase family C50 CHAT PF12770.7 RLN80962.1 - 4e-05 23.2 0.1 7.6e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 CHAT domain MetOD2 PF18548.1 RLN80962.1 - 0.14 12.2 0.4 0.45 10.6 0.3 1.9 2 0 0 2 2 2 0 Metanogen output domain 2 BPL_LplA_LipB PF03099.19 RLN80963.1 - 5.2e-11 42.6 0.0 8.1e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family MIX PF18529.1 RLN80963.1 - 0.022 14.5 0.1 0.099 12.3 0.1 1.9 1 1 1 2 2 2 0 Mitochondrial membrane-anchored proteins ADH_N_assoc PF13823.6 RLN80963.1 - 1.1 9.2 6.6 3.4 7.7 1.1 2.9 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated Calx-beta PF03160.14 RLN80964.1 - 1.6e-25 89.2 0.0 4.9e-07 29.8 0.0 5.0 5 1 0 5 5 5 4 Calx-beta domain TNFR_c6 PF00020.18 RLN80964.1 - 6.9e-09 36.0 45.1 0.00084 19.7 6.2 5.6 3 2 3 6 6 6 4 TNFR/NGFR cysteine-rich region DUF4843 PF16132.5 RLN80964.1 - 0.045 13.3 0.1 0.92 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4843) Methyltransf_16 PF10294.9 RLN80965.1 - 2.4e-13 50.2 0.0 3.7e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 RLN80965.1 - 0.17 11.2 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF1351 PF07083.11 RLN80966.1 - 0.042 13.6 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) DUF1104 PF06518.11 RLN80966.1 - 0.2 12.0 0.7 1.5 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Flavoprotein PF02441.19 RLN80967.1 - 1.3e-10 41.2 0.0 1.4e-10 41.2 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein SNF2_N PF00176.23 RLN80968.1 - 8e-54 182.7 0.0 1.5e-53 181.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN80968.1 - 2.1e-16 60.2 0.0 4.3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RLN80968.1 - 3.1e-07 30.3 0.0 7.4e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 RLN80968.1 - 2.7e-05 24.2 0.0 2.7e-05 24.2 0.0 2.5 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Nucleo_P87 PF07267.11 RLN80968.1 - 0.0041 16.0 7.1 0.0068 15.3 7.1 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 HDA2-3 PF11496.8 RLN80968.1 - 0.071 12.3 0.0 0.22 10.7 0.0 1.7 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Ribosomal_60s PF00428.19 RLN80969.1 - 3.6e-13 49.9 1.9 4.4e-13 49.6 1.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein RE_BstXI PF09552.10 RLN80970.1 - 0.12 11.5 0.8 9.5 5.3 0.1 2.1 2 0 0 2 2 2 0 BstXI restriction endonuclease DUF4427 PF14468.6 RLN80970.1 - 0.16 12.0 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) Peptidase_U32_C PF16325.5 RLN80971.1 - 0.15 12.4 0.1 0.56 10.5 0.1 2.0 1 0 0 1 1 1 0 Peptidase family U32 C-terminal domain GATase_6 PF13522.6 RLN80972.1 - 1.4e-16 60.9 0.0 6.7e-16 58.7 0.0 2.1 1 1 1 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 RLN80972.1 - 2.6e-16 59.7 0.0 1.6e-15 57.1 0.0 2.3 3 0 0 3 3 3 1 Glutamine amidotransferase domain GATase_4 PF13230.6 RLN80972.1 - 1.2e-09 37.5 0.0 2.5e-09 36.4 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferases class-II Pribosyltran PF00156.27 RLN80972.1 - 6.4e-09 35.5 0.0 1.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PA PF02225.22 RLN80972.1 - 0.053 13.6 0.5 0.18 11.8 0.1 2.0 2 0 0 2 2 2 0 PA domain GDPD PF03009.17 RLN80972.1 - 0.065 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Cse1 PF08506.10 RLN80973.1 - 5e-127 423.7 0.8 8.4e-127 423.0 0.8 1.4 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 RLN80973.1 - 1.2e-89 300.8 2.6 8.8e-85 284.8 1.1 2.9 2 1 1 3 3 3 2 CAS/CSE protein, C-terminus IBN_N PF03810.19 RLN80973.1 - 7.6e-16 57.8 0.1 2.2e-15 56.3 0.1 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT PF02985.22 RLN80973.1 - 0.002 18.2 0.4 10 6.7 0.1 4.2 3 0 0 3 3 3 1 HEAT repeat Xpo1 PF08389.12 RLN80973.1 - 0.0028 17.7 3.0 0.034 14.2 0.1 4.3 5 0 0 5 5 5 1 Exportin 1-like protein HEAT_2 PF13646.6 RLN80973.1 - 0.026 14.9 0.1 19 5.7 0.0 3.3 2 0 0 2 2 2 0 HEAT repeats Ank_2 PF12796.7 RLN80974.1 - 8.3e-42 141.7 8.4 8.3e-12 45.5 0.2 6.5 2 2 4 6 6 6 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN80974.1 - 9.8e-32 105.4 13.1 0.00012 22.2 0.0 10.5 11 0 0 11 11 11 7 Ankyrin repeat Ank PF00023.30 RLN80974.1 - 1.6e-31 107.3 16.2 2.6e-05 24.4 0.1 10.2 10 0 0 10 10 10 5 Ankyrin repeat Ank_4 PF13637.6 RLN80974.1 - 2.9e-30 104.2 9.3 4.3e-08 33.5 0.1 8.1 6 2 3 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN80974.1 - 2e-29 101.3 17.1 1.4e-06 28.4 0.0 8.9 4 3 6 10 10 10 8 Ankyrin repeats (many copies) FYVE PF01363.21 RLN80974.1 - 3.2e-19 68.8 10.0 6.7e-19 67.8 10.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger BTB PF00651.31 RLN80974.1 - 2.4e-11 43.8 0.1 1.1e-10 41.8 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain FYVE_2 PF02318.16 RLN80974.1 - 0.039 14.2 6.4 0.095 12.9 6.4 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger IBR PF01485.21 RLN80974.1 - 0.3 11.3 7.3 0.97 9.7 7.3 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain PDZ PF00595.24 RLN80975.1 - 0.0071 16.7 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Cyclin_C PF02984.19 RLN80976.1 - 5.3e-16 58.8 0.0 1.1e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 RLN80976.1 - 2.1e-13 50.1 0.2 9.5e-13 48.0 0.1 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain AAA_6 PF12774.7 RLN80977.1 - 2.8e-157 522.8 0.0 1.4e-156 520.5 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN80977.1 - 1.2e-126 423.1 7.1 1.2e-126 423.1 7.1 3.2 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RLN80977.1 - 1.4e-102 342.5 0.1 4.4e-101 337.6 0.0 2.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RLN80977.1 - 2.9e-93 311.1 0.4 2.9e-93 311.1 0.4 3.1 2 0 0 2 2 2 1 ATP-binding dynein motor region Dynein_C PF18199.1 RLN80977.1 - 5.1e-84 282.1 0.4 3e-82 276.3 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 RLN80977.1 - 2.8e-77 258.3 0.1 8.1e-76 253.6 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RLN80977.1 - 1.5e-57 194.0 0.0 1e-56 191.2 0.0 2.5 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RLN80977.1 - 4.6e-45 152.5 0.0 2.7e-42 143.6 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 RLN80977.1 - 6.7e-43 147.0 5.6 6.7e-43 147.0 5.6 2.4 3 0 0 3 3 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 RLN80977.1 - 8.6e-33 113.2 0.5 3.6e-32 111.2 0.5 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RLN80977.1 - 6.4e-22 77.6 0.5 3.2e-19 69.0 0.2 3.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 RLN80977.1 - 5.3e-12 45.9 0.0 0.00031 20.8 0.0 5.9 5 1 0 5 5 4 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 RLN80977.1 - 1.7e-08 34.4 0.0 2.5e-05 24.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 RLN80977.1 - 8.6e-07 29.4 2.1 0.088 13.2 0.0 4.5 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 RLN80977.1 - 7.3e-05 22.0 0.0 0.00024 20.2 0.0 1.9 1 0 0 1 1 1 1 Type II/IV secretion system protein RNA_helicase PF00910.22 RLN80977.1 - 0.00053 20.3 0.0 0.97 9.8 0.0 3.4 2 0 0 2 2 2 1 RNA helicase DUF4349 PF14257.6 RLN80977.1 - 0.0023 17.4 0.5 0.0023 17.4 0.5 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4349) AAA_18 PF13238.6 RLN80977.1 - 0.0064 17.0 0.5 3.9 8.0 0.0 4.7 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.6 RLN80977.1 - 0.028 14.7 0.1 2.7 8.3 0.0 3.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 RLN80977.1 - 0.033 14.6 4.1 11 6.3 0.0 5.2 5 0 0 5 5 5 0 AAA ATPase domain ATPase_2 PF01637.18 RLN80977.1 - 0.046 13.6 0.4 0.28 11.1 0.0 2.7 3 0 0 3 3 1 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 RLN80977.1 - 0.046 13.1 0.1 8.1 5.8 0.0 3.6 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI DUF87 PF01935.17 RLN80977.1 - 0.048 13.7 0.0 0.048 13.7 0.0 3.8 3 0 0 3 3 3 0 Helicase HerA, central domain E2F_CC-MB PF16421.5 RLN80977.1 - 0.055 13.8 0.6 0.29 11.5 0.6 2.3 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain IstB_IS21 PF01695.17 RLN80977.1 - 0.073 12.8 0.0 0.46 10.2 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.6 RLN80977.1 - 0.1 12.9 4.0 0.8 10.0 0.0 3.7 5 0 0 5 5 2 0 AAA domain Roc PF08477.13 RLN80977.1 - 0.15 12.2 0.2 0.87 9.8 0.0 2.5 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase DEAD PF00270.29 RLN80977.1 - 0.16 11.7 0.0 0.68 9.7 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase Sigma54_activat PF00158.26 RLN80977.1 - 0.16 11.6 0.1 0.56 9.9 0.0 1.9 2 0 0 2 2 1 0 Sigma-54 interaction domain CK2S PF15011.6 RLN80977.1 - 0.45 10.4 6.9 0.22 11.4 0.6 3.3 2 0 0 2 2 2 0 Casein Kinase 2 substrate Snapin_Pallidin PF14712.6 RLN80977.1 - 0.56 10.7 10.3 2.7 8.5 2.4 3.7 2 0 0 2 2 2 0 Snapin/Pallidin Plasmid_RAQPRD PF09686.10 RLN80977.1 - 0.83 9.9 7.9 1.7 8.9 0.0 5.0 4 1 1 5 5 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF3740 PF12548.8 RLN80977.1 - 1.2 9.5 3.6 0.61 10.5 0.3 2.2 2 0 0 2 2 1 0 Sulfatase protein Baculo_PEP_C PF04513.12 RLN80977.1 - 1.3 9.0 13.7 1.5 8.9 1.4 4.9 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CCDC-167 PF15188.6 RLN80977.1 - 4 7.8 5.7 25 5.3 0.2 4.2 3 0 0 3 3 2 0 Coiled-coil domain-containing protein 167 DUF4423 PF14394.6 RLN80977.1 - 7.2 6.3 9.7 0.29 10.8 0.1 3.1 3 0 0 3 3 2 0 Domain of unknown function (DUF4423) DUF948 PF06103.11 RLN80977.1 - 9.7 6.5 10.9 2 8.8 0.2 4.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Transglut_core PF01841.19 RLN80978.1 - 0.049 14.1 0.0 0.28 11.7 0.0 2.2 2 0 0 2 2 2 0 Transglutaminase-like superfamily AAA_18 PF13238.6 RLN80996.1 - 7.6e-05 23.3 1.0 0.0021 18.6 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 RLN80996.1 - 0.00025 21.3 0.1 0.00072 19.8 0.1 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 RLN80996.1 - 0.00039 19.8 0.0 0.00091 18.6 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 RLN80996.1 - 0.0012 18.7 0.1 0.089 12.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA PF00004.29 RLN80996.1 - 0.0036 17.7 0.7 0.26 11.7 0.3 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 RLN80996.1 - 0.0069 16.6 0.2 0.0069 16.6 0.2 3.0 3 1 1 4 4 3 1 AAA domain APS_kinase PF01583.20 RLN80996.1 - 0.0078 16.1 0.1 0.018 14.9 0.1 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_5 PF07728.14 RLN80996.1 - 0.013 15.5 0.2 0.053 13.5 0.1 2.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 RLN80996.1 - 0.041 13.6 0.0 0.099 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN80996.1 - 0.042 13.4 4.2 0.11 12.0 1.7 2.6 2 1 0 2 2 2 0 AAA domain CbiA PF01656.23 RLN80996.1 - 0.042 13.9 0.3 0.098 12.7 0.2 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Sigma54_activat PF00158.26 RLN80996.1 - 0.07 12.8 0.0 0.35 10.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 RLN80996.1 - 0.13 12.2 1.6 11 5.9 0.1 2.3 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 RLN80996.1 - 0.18 12.2 0.0 0.65 10.4 0.0 2.1 1 1 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 RLN80996.1 - 0.22 12.1 2.1 0.66 10.5 2.1 2.1 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 RLN80996.1 - 0.42 11.0 8.9 4 7.8 8.9 2.5 1 1 0 1 1 1 0 AAA ATPase domain Sox_N PF12444.8 RLN80996.1 - 0.95 10.6 10.6 26 6.0 0.1 3.8 3 0 0 3 3 3 0 Sox developmental protein N terminal BSP_II PF05432.11 RLN80996.1 - 1.8 8.2 13.7 0.15 11.7 8.5 1.7 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) TRAP_alpha PF03896.16 RLN80996.1 - 6.6 5.8 6.1 9.2 5.4 1.8 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit WW PF00397.26 RLN81027.1 - 8.1e-19 67.4 14.1 6.4e-10 39.0 1.6 2.6 2 0 0 2 2 2 2 WW domain FF PF01846.19 RLN81027.1 - 1.2e-13 51.0 1.7 3.1e-05 24.1 0.2 3.8 3 0 0 3 3 3 2 FF domain Glyco_hyd_101C PF17451.2 RLN81027.1 - 0.0062 16.8 2.8 1.4 9.2 0.6 3.0 1 1 1 2 2 2 2 Glycosyl hydrolase 101 beta sandwich domain PUFD PF16553.5 RLN81028.1 - 0.041 14.0 0.1 0.075 13.2 0.1 1.5 1 0 0 1 1 1 0 BCORL-PCGF1-binding domain DUF2892 PF11127.8 RLN81029.1 - 7.7 6.6 7.6 0.52 10.4 2.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) NDK PF00334.19 RLN81031.1 - 6.1e-52 175.2 0.0 6.8e-52 175.1 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Pkinase PF00069.25 RLN81032.1 - 8.4e-52 176.1 0.0 1e-51 175.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN81032.1 - 1.4e-44 152.4 0.0 1.6e-44 152.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN81032.1 - 0.00049 20.1 0.1 0.0069 16.3 0.0 2.5 1 1 2 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN81032.1 - 0.024 13.6 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DIOX_N PF14226.6 RLN81033.1 - 2.9e-23 82.8 0.0 4.7e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 RLN81033.1 - 1e-17 64.4 0.0 2.1e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BBS2_C PF14782.6 RLN81035.1 - 0.018 13.8 0.9 0.023 13.5 0.9 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Dynein_C PF18199.1 RLN81035.1 - 0.042 13.1 0.2 0.05 12.8 0.2 1.1 1 0 0 1 1 1 0 Dynein heavy chain C-terminal domain DASH_Dam1 PF08653.10 RLN81035.1 - 0.05 13.4 2.0 7.1 6.5 0.2 2.6 1 1 1 2 2 2 0 DASH complex subunit Dam1 Glyco_trans_1_2 PF13524.6 RLN81035.1 - 0.12 12.8 0.3 0.12 12.8 0.3 1.6 2 0 0 2 2 2 0 Glycosyl transferases group 1 SART-1 PF03343.13 RLN81036.1 - 2.7e-83 280.6 87.5 2.7e-67 227.8 72.2 3.9 2 1 1 3 3 3 2 SART-1 family Neurensin PF14927.6 RLN81037.1 - 0.13 12.0 2.5 0.19 11.4 0.7 2.2 1 1 0 2 2 2 0 Neurensin TNFR_16_TM PF18422.1 RLN81037.1 - 0.31 11.0 1.5 1.3 9.1 1.5 2.0 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Abhydrolase_9_N PF15420.6 RLN81037.1 - 0.52 10.3 7.9 0.4 10.7 5.7 2.0 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus COX2_TM PF02790.15 RLN81037.1 - 7.9 6.7 6.0 8.8 6.5 0.0 3.5 4 1 0 4 4 4 0 Cytochrome C oxidase subunit II, transmembrane domain DUF3391 PF11871.8 RLN81038.1 - 0.19 12.3 0.0 0.28 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Trypsin_2 PF13365.6 RLN81063.1 - 4.3e-17 63.4 0.7 4.3e-17 63.4 0.7 1.9 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 RLN81063.1 - 0.00034 20.5 7.0 0.00066 19.5 4.4 2.5 2 1 0 2 2 2 1 Trypsin Peptidase_S46 PF10459.9 RLN81063.1 - 0.0015 17.3 0.2 0.0015 17.3 0.2 1.7 2 0 0 2 2 2 1 Peptidase S46 RGP PF03214.13 RLN81063.1 - 0.038 13.2 0.2 0.071 12.3 0.2 1.3 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide FYVE PF01363.21 RLN81064.1 - 0.0024 18.0 8.1 0.014 15.5 7.9 2.1 1 1 1 2 2 2 1 FYVE zinc finger DUF2180 PF09947.9 RLN81064.1 - 0.019 14.9 2.6 2.1 8.4 2.5 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) zf-piccolo PF05715.13 RLN81064.1 - 0.42 10.8 5.1 1.6 8.9 5.1 1.9 1 1 1 2 2 2 0 Piccolo Zn-finger DZR PF12773.7 RLN81064.1 - 0.78 9.8 9.2 94 3.2 9.2 2.5 1 1 0 1 1 1 0 Double zinc ribbon DUF1195 PF06708.11 RLN81065.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) Apolipoprotein PF01442.18 RLN81066.1 - 0.25 11.2 5.4 0.23 11.3 0.7 3.1 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain Chlorosome_CsmC PF11098.8 RLN81066.1 - 1.1 9.2 7.0 0.14 12.1 1.6 2.4 2 0 0 2 2 2 0 Chlorosome envelope protein C Cyt_c_ox_IV PF12270.8 RLN81066.1 - 1.3 9.1 5.8 0.38 10.9 0.1 2.6 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV Nop14 PF04147.12 RLN81095.1 - 1.1 7.4 12.3 1.4 7.1 12.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RLN81095.1 - 3.9 6.8 12.2 5.8 6.3 12.2 1.3 1 0 0 1 1 1 0 SDA1 P2X_receptor PF00864.19 RLN81127.1 - 0.13 11.3 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 ATP P2X receptor Metallophos PF00149.28 RLN81128.1 - 2.3e-10 41.3 0.0 4.6e-10 40.3 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RLN81128.1 - 0.02 15.1 0.0 0.37 11.0 0.1 2.3 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Protocadherin PF08374.11 RLN81128.1 - 0.02 14.9 0.1 0.031 14.3 0.1 1.2 1 0 0 1 1 1 0 Protocadherin SID-1_RNA_chan PF13965.6 RLN81128.1 - 0.27 9.6 0.0 0.36 9.2 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Pro_isomerase PF00160.21 RLN81129.1 - 1.4e-51 174.9 0.1 3.1e-51 173.8 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 RLN81129.1 - 1.4e-14 54.2 0.1 0.00022 22.0 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN81129.1 - 8.4e-06 26.0 0.0 0.52 10.6 0.0 4.0 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN81129.1 - 0.0004 19.4 0.1 0.6 9.0 0.0 3.0 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein MtN3_slv PF03083.16 RLN81133.1 - 8.6e-07 28.9 1.7 1e-06 28.6 1.7 1.1 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange Stimulus_sens_1 PF13756.6 RLN81133.1 - 0.041 14.5 0.0 0.045 14.3 0.0 1.1 1 0 0 1 1 1 0 Stimulus-sensing domain PsbN PF02468.15 RLN81133.1 - 0.22 11.4 0.2 0.22 11.4 0.2 1.9 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) MtN3_slv PF03083.16 RLN81134.1 - 5e-26 90.6 14.4 1.9e-15 56.7 4.4 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Prominin PF05478.11 RLN81134.1 - 0.04 11.9 0.5 0.056 11.4 0.5 1.1 1 0 0 1 1 1 0 Prominin Pox_A14 PF05767.12 RLN81134.1 - 0.064 13.4 1.2 0.21 11.8 1.2 1.9 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF4131 PF13567.6 RLN81134.1 - 3.7 7.2 9.0 1.4 8.6 5.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Metallophos PF00149.28 RLN81136.1 - 2.2e-11 44.7 0.9 3.5e-11 44.0 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RLN81136.1 - 0.00076 19.7 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Oxidored_FMN PF00724.20 RLN81137.1 - 6.1e-81 272.3 0.0 7.5e-81 272.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF2277 PF10041.9 RLN81137.1 - 0.11 12.9 0.2 0.25 11.7 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) MtN3_slv PF03083.16 RLN81138.1 - 1.4e-26 92.3 11.0 1.2e-15 57.3 0.9 2.7 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange MtN3_slv PF03083.16 RLN81139.1 - 3.7e-25 87.8 9.4 1.9e-15 56.6 3.3 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Prominin PF05478.11 RLN81139.1 - 0.036 12.0 0.6 0.049 11.6 0.6 1.1 1 0 0 1 1 1 0 Prominin PQ-loop PF04193.14 RLN81139.1 - 0.19 11.5 0.2 0.19 11.5 0.2 3.5 4 0 0 4 4 4 0 PQ loop repeat MerC PF03203.14 RLN81139.1 - 1.5 9.3 11.1 5 7.6 10.9 2.0 1 1 0 1 1 1 0 MerC mercury resistance protein MtN3_slv PF03083.16 RLN81141.1 - 4.4e-15 55.5 2.1 4.4e-15 55.5 2.1 2.2 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange Phage_holin_5_2 PF16079.5 RLN81141.1 - 0.26 11.6 2.7 0.45 10.9 0.3 2.2 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V MASE3 PF17159.4 RLN81141.1 - 0.58 9.7 7.1 0.24 11.0 1.5 2.0 1 1 1 2 2 2 0 Membrane-associated sensor domain MtN3_slv PF03083.16 RLN81142.1 - 1.8e-26 92.0 15.2 9.5e-17 60.8 4.6 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Prominin PF05478.11 RLN81142.1 - 0.27 9.2 1.0 0.37 8.7 1.0 1.1 1 0 0 1 1 1 0 Prominin MerC PF03203.14 RLN81142.1 - 5.7 7.4 16.0 8.9 6.8 13.2 2.7 1 1 1 2 2 2 0 MerC mercury resistance protein SBP_bac_11 PF13531.6 RLN81165.1 - 6.3e-34 117.7 0.1 9.8e-34 117.1 0.1 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 RLN81165.1 - 5.7e-07 29.8 0.1 1.2e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 RLN81165.1 - 0.002 17.6 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein ODV-E18 PF10717.9 RLN81165.1 - 0.047 13.6 1.4 0.11 12.4 1.4 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Retrotran_gag_2 PF14223.6 RLN81166.1 - 2.8e-10 40.0 0.2 5.6e-10 39.0 0.2 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Histone_HNS PF00816.21 RLN81166.1 - 0.2 12.5 5.1 0.74 10.7 5.1 1.9 1 0 0 1 1 1 0 H-NS histone family INTAP PF16617.5 RLN81166.1 - 0.37 11.2 3.2 2.6 8.4 1.6 2.5 2 0 0 2 2 2 0 Intersectin and clathrin adaptor AP2 binding region Retrotran_gag_2 PF14223.6 RLN81167.1 - 6.5e-08 32.3 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DAZAP2 PF11029.8 RLN81167.1 - 0.0076 17.2 0.2 0.0076 17.2 0.2 3.4 4 0 0 4 4 4 1 DAZ associated protein 2 (DAZAP2) PH PF00169.29 RLN81168.1 - 3.4e-08 33.9 0.0 9.8e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 RLN81168.1 - 0.00017 21.8 0.0 0.0007 19.9 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 RLN81168.1 - 0.00046 20.6 1.5 0.0093 16.4 0.1 3.6 3 1 0 3 3 3 1 Pleckstrin homology domain Seryl_tRNA_N PF02403.22 RLN81168.1 - 0.0019 18.4 37.1 1.3 9.3 7.9 4.4 3 1 1 4 4 4 4 Seryl-tRNA synthetase N-terminal domain WW PF00397.26 RLN81168.1 - 0.0026 17.8 1.0 0.005 16.9 1.0 1.5 1 0 0 1 1 1 1 WW domain PH_8 PF15409.6 RLN81168.1 - 0.0052 17.0 0.0 0.015 15.6 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain ABC_tran_CTD PF16326.5 RLN81168.1 - 0.0062 16.8 3.1 0.0062 16.8 3.1 4.9 2 1 3 5 5 5 1 ABC transporter C-terminal domain FlxA PF14282.6 RLN81168.1 - 0.021 14.8 1.6 0.021 14.8 1.6 3.7 2 1 1 3 3 3 0 FlxA-like protein GAS PF13851.6 RLN81168.1 - 0.35 10.2 36.6 0.26 10.6 1.9 4.4 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 RLN81168.1 - 8.3 7.1 31.3 1.9 9.2 1.8 4.4 2 2 2 4 4 4 0 Initiation control protein YabA Taxilin PF09728.9 RLN81168.1 - 8.7 5.4 43.0 1.1 8.4 4.5 4.2 2 2 2 4 4 4 0 Myosin-like coiled-coil protein ABC_membrane PF00664.23 RLN81169.1 - 1.9e-28 99.9 8.1 2.9e-28 99.3 8.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN81169.1 - 1.4e-27 96.8 0.0 2.8e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN81169.1 - 6e-08 32.4 0.1 6.7e-06 25.7 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RLN81169.1 - 1.3e-05 25.7 0.1 7.7e-05 23.1 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RLN81169.1 - 0.0002 21.6 0.2 0.0027 18.0 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 RLN81169.1 - 0.00025 21.0 0.1 0.033 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN81169.1 - 0.00053 19.9 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 RLN81169.1 - 0.0041 17.5 0.1 0.086 13.3 0.0 2.7 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 RLN81169.1 - 0.0062 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_24 PF13479.6 RLN81169.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 RLN81169.1 - 0.025 15.1 0.0 0.057 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RLN81169.1 - 0.035 13.7 0.0 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 RLN81169.1 - 0.043 14.0 1.0 0.25 11.6 0.1 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 RLN81169.1 - 0.051 13.5 0.1 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 NACHT domain ABC_ATPase PF09818.9 RLN81169.1 - 0.052 12.3 0.1 1.4 7.6 0.1 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_33 PF13671.6 RLN81169.1 - 0.056 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 RLN81169.1 - 0.069 12.9 0.0 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 RLN81169.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 RLN81169.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain PrmA PF06325.13 RLN81170.1 - 1.3e-10 41.2 0.0 2e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 RLN81170.1 - 9.3e-10 39.1 0.0 4.3e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN81170.1 - 2.5e-06 28.1 0.0 8.2e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 RLN81170.1 - 2.8e-05 23.7 0.0 0.00011 21.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 RLN81170.1 - 4.9e-05 23.2 0.0 0.00011 22.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 RLN81170.1 - 0.00059 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN81170.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 RLN81170.1 - 0.0022 17.9 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CMAS PF02353.20 RLN81170.1 - 0.0024 17.2 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5_C PF17286.2 RLN81170.1 - 0.0044 16.9 0.1 0.0071 16.2 0.1 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_9 PF08003.11 RLN81170.1 - 0.038 12.9 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_24 PF13578.6 RLN81170.1 - 0.081 14.0 0.0 0.17 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 RLN81170.1 - 0.091 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_16 PF10294.9 RLN81170.1 - 0.093 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PALP PF00291.25 RLN81170.1 - 0.094 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Ricin_B_lectin PF00652.22 RLN81171.1 - 2.1e-41 141.1 28.5 9.4e-16 58.2 6.5 3.6 2 1 0 3 3 3 3 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 RLN81171.1 - 2.2e-13 50.0 6.4 0.00078 19.1 0.1 4.3 3 1 1 4 4 4 4 Cytolethal distending toxin A/C domain RicinB_lectin_2 PF14200.6 RLN81171.1 - 1.4e-12 48.2 32.4 0.00094 19.9 4.7 6.5 2 2 4 6 6 6 6 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_17 PF00332.18 RLN81171.1 - 5.7e-11 42.6 4.2 5.1e-10 39.4 3.2 2.5 2 1 0 2 2 2 1 Glycosyl hydrolases family 17 DUF346 PF03984.13 RLN81171.1 - 0.11 12.3 0.2 0.11 12.3 0.2 2.8 3 0 0 3 3 3 0 Repeat of unknown function (DUF346) SOCS PF12610.8 RLN81172.1 - 0.031 14.7 1.1 0.084 13.3 1.1 1.7 1 0 0 1 1 1 0 Suppressor of cytokine signalling PUL PF08324.11 RLN81173.1 - 3.9e-36 124.7 4.3 5.1e-36 124.3 4.3 1.1 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 RLN81173.1 - 6.7e-23 81.1 0.0 1.2e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 RLN81173.1 - 2e-17 63.2 7.2 0.004 18.0 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ELO PF01151.18 RLN81174.1 - 3.6e-49 167.6 21.6 4.7e-49 167.2 21.6 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family CCSMST1 PF15013.6 RLN81174.1 - 0.15 12.2 3.8 0.83 9.9 0.3 2.3 1 1 1 2 2 2 0 CCSMST1 family Peptidase_S41 PF03572.18 RLN81175.1 - 1.5e-14 53.9 0.0 2.5e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S41 Tricorn_C1 PF14684.6 RLN81175.1 - 0.16 12.0 0.2 0.37 10.9 0.2 1.5 1 0 0 1 1 1 0 Tricorn protease C1 domain Gp_dh_N PF00044.24 RLN81205.1 - 3.8e-39 133.1 0.0 4.7e-39 132.8 0.0 1.1 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 RLN81205.1 - 0.024 14.8 0.1 0.066 13.3 0.1 1.9 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Pkinase_Tyr PF07714.17 RLN81206.1 - 3.9e-20 72.2 0.0 2.5e-17 63.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN81206.1 - 1.4e-16 60.7 0.0 1.9e-15 56.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 RLN81206.1 - 2e-06 27.4 0.2 4.5e-06 26.3 0.2 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 RLN81206.1 - 2.9e-06 27.5 0.9 6.6e-06 26.4 0.2 2.1 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RLN81206.1 - 0.012 15.6 5.0 3.2 8.0 0.9 3.3 3 0 0 3 3 3 0 Leucine Rich repeat DUF4083 PF13314.6 RLN81206.1 - 0.16 11.9 0.1 0.36 10.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) zf-RING_2 PF13639.6 RLN81207.1 - 3.7e-08 33.5 2.5 9.6e-08 32.2 2.5 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN81207.1 - 2e-07 30.7 2.3 3.9e-07 29.8 2.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN81207.1 - 2.7e-06 27.6 1.9 5.8e-06 26.5 1.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RLN81207.1 - 3.5e-06 26.9 1.4 6.9e-06 25.9 1.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RLN81207.1 - 5.2e-06 26.2 1.4 9.6e-06 25.4 1.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN81207.1 - 7.6e-05 22.5 1.4 0.00015 21.6 1.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN81207.1 - 0.0031 17.3 1.3 0.0064 16.3 1.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Rtf2 PF04641.12 RLN81207.1 - 0.0042 16.5 0.7 0.005 16.3 0.7 1.4 1 1 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.6 RLN81207.1 - 0.0068 16.4 2.6 0.0068 16.4 2.6 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 RLN81207.1 - 0.0085 15.8 0.5 0.0085 15.8 0.5 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 RLN81207.1 - 0.031 14.3 0.5 0.066 13.3 0.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn-ribbon_8 PF09723.10 RLN81207.1 - 0.031 14.4 1.4 0.031 14.4 1.4 1.9 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_4 PF14570.6 RLN81207.1 - 0.056 13.2 1.9 0.057 13.2 0.5 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Arabinose_Iso_C PF11762.8 RLN81207.1 - 0.11 12.3 0.3 1.9 8.3 0.3 2.3 1 1 0 1 1 1 0 L-arabinose isomerase C-terminal domain zf-C3H2C3 PF17122.5 RLN81207.1 - 0.12 12.4 1.6 0.27 11.3 1.6 1.6 1 0 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 RLN81207.1 - 1.3 8.7 7.3 0.098 12.3 1.9 1.9 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C2H2_jaz PF12171.8 RLN81208.1 - 3.9e-08 33.4 5.1 1.1e-07 31.9 5.1 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RLN81208.1 - 6.5e-07 29.5 2.9 1.3e-06 28.6 2.9 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DnaJ PF00226.31 RLN81208.1 - 1.4e-05 25.1 0.0 5.3e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_2 PF12756.7 RLN81208.1 - 3.8e-05 24.0 0.4 0.00015 22.0 0.4 2.0 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 RLN81208.1 - 0.0011 19.7 0.9 0.0025 18.5 0.4 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 RLN81208.1 - 0.021 15.3 1.7 0.041 14.3 1.7 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-DBF PF07535.12 RLN81208.1 - 0.034 14.3 0.3 0.083 13.0 0.3 1.6 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_6 PF13912.6 RLN81208.1 - 0.22 11.6 3.2 0.23 11.5 1.8 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger Arf PF00025.21 RLN81209.1 - 1e-22 80.4 0.0 4.5e-15 55.5 0.0 2.4 1 1 1 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 RLN81209.1 - 0.0059 15.8 0.0 2.5 7.2 0.0 2.8 1 1 2 3 3 3 2 G-protein alpha subunit Roc PF08477.13 RLN81209.1 - 0.0073 16.5 0.0 0.022 15.0 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 RLN81209.1 - 0.013 15.8 0.0 0.066 13.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 RLN81209.1 - 0.023 14.9 0.0 0.053 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 RLN81209.1 - 0.024 14.1 0.0 0.059 12.8 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 RLN81209.1 - 0.027 14.8 0.9 0.12 12.8 0.9 2.3 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 RLN81209.1 - 0.031 14.2 0.1 0.073 13.0 0.1 1.6 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 RLN81209.1 - 0.041 14.4 0.5 0.14 12.6 0.1 2.0 2 0 0 2 2 2 0 ABC transporter TsaE PF02367.17 RLN81209.1 - 0.044 13.8 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 RLN81209.1 - 0.065 12.9 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 RLN81209.1 - 0.088 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF2026 PF09641.10 RLN81209.1 - 0.13 11.9 0.1 0.86 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2026) NTPase_1 PF03266.15 RLN81209.1 - 0.2 11.5 0.9 0.36 10.7 0.1 1.8 2 0 0 2 2 2 0 NTPase AAA_28 PF13521.6 RLN81209.1 - 0.21 11.8 1.8 0.43 10.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain bZIP_1 PF00170.21 RLN81210.1 - 0.015 15.4 7.1 0.45 10.6 6.4 2.5 2 1 0 2 2 2 0 bZIP transcription factor AKAP7_RIRII_bdg PF10470.9 RLN81210.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein DUF1140 PF06600.11 RLN81210.1 - 0.16 12.4 0.1 0.27 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1140) Palm_thioest PF02089.15 RLN81241.1 - 2.6e-27 96.2 0.0 2.9e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase NdhO PF11910.8 RLN81241.1 - 0.088 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Cyanobacterial and plant NDH-1 subunit O DUF4605 PF15378.6 RLN81242.1 - 0.015 15.2 0.5 0.015 15.2 0.5 3.9 5 0 0 5 5 5 0 Domain of unknown function (DUF4605) DUF4605 PF15378.6 RLN81243.1 - 0.017 15.0 0.1 0.017 15.0 0.1 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4605) GAF PF01590.26 RLN81244.1 - 0.0004 21.0 0.5 0.00053 20.6 0.5 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 RLN81244.1 - 0.11 12.9 0.1 0.27 11.6 0.1 1.7 1 1 1 2 2 2 0 GAF domain MbeD_MobD PF04899.12 RLN81245.1 - 1.9 8.6 8.5 7.8 6.7 0.2 2.9 3 0 0 3 3 3 0 MbeD/MobD like LPP PF04728.13 RLN81245.1 - 3.3 8.2 5.4 5.5 7.4 0.2 3.2 3 0 0 3 3 3 0 Lipoprotein leucine-zipper MerR-DNA-bind PF09278.11 RLN81245.1 - 5.8 7.5 13.1 3.1 8.4 0.1 4.4 4 0 0 4 4 4 0 MerR, DNA binding TT_ORF2 PF02957.15 RLN81245.1 - 8 7.4 7.3 18 6.3 0.1 3.3 3 0 0 3 3 3 0 TT viral ORF2 MULE PF10551.9 RLN81271.1 - 0.026 14.9 0.1 0.081 13.3 0.0 1.9 2 0 0 2 2 2 0 MULE transposase domain Chromo PF00385.24 RLN81271.1 - 0.031 14.2 0.2 0.18 11.7 0.2 2.3 1 1 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF641 PF04859.12 RLN81272.1 - 0.012 15.9 2.3 0.012 15.9 2.3 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) MPS2 PF17060.5 RLN81272.1 - 0.036 13.4 5.4 0.048 12.9 5.4 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 TSA PF03249.13 RLN81272.1 - 0.21 10.3 7.9 0.26 10.0 7.9 1.1 1 0 0 1 1 1 0 Type specific antigen FapA PF03961.13 RLN81272.1 - 0.85 8.2 6.2 1.1 7.8 6.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 RLN81272.1 - 0.91 9.0 11.1 1.3 8.5 11.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.11 RLN81272.1 - 6.1 6.9 17.0 9.2 6.3 17.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CwsA PF10814.8 RLN81272.1 - 6.8 6.9 6.4 2.1 8.5 3.5 1.6 1 1 1 2 2 2 0 Cell wall synthesis protein CwsA USP8_interact PF08941.10 RLN81272.1 - 8.7 6.1 9.9 5.1 6.9 0.1 2.1 2 0 0 2 2 2 0 USP8 interacting HTH_57 PF18679.1 RLN81272.1 - 9.4 6.6 8.3 12 6.2 4.2 2.1 1 1 1 2 2 2 0 ThcOx helix turn helix domain SecA_DEAD PF07517.14 RLN81295.1 - 8e-10 38.5 0.0 8.5e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 SecA DEAD-like domain DUF5062 PF16691.5 RLN81296.1 - 0.17 12.0 0.9 7.3 6.8 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5062) DivIC PF04977.15 RLN81297.1 - 1.5 8.7 4.1 3.9 7.3 1.1 2.5 2 0 0 2 2 2 0 Septum formation initiator ArfGap PF01412.18 RLN81298.1 - 2.7e-06 27.4 0.5 2.7e-06 27.4 0.5 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf CDC45 PF02724.14 RLN81298.1 - 0.0028 16.0 0.1 0.0028 16.0 0.1 1.6 2 0 0 2 2 2 1 CDC45-like protein DUF4666 PF15697.5 RLN81298.1 - 1.9 9.2 12.2 0.2 12.3 4.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) Neur_chan_memb PF02932.16 RLN81298.1 - 2.8 7.9 9.1 2 8.4 2.8 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PALP PF00291.25 RLN81299.1 - 3.4e-69 233.5 0.4 4.6e-69 233.0 0.4 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TruB_C_2 PF16198.5 RLN81300.1 - 7.4e-22 77.3 0.9 1.4e-21 76.4 0.9 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 RLN81300.1 - 4.8e-20 71.3 2.0 4.8e-20 71.3 2.0 2.6 2 1 1 3 3 3 1 PUA domain Coilin_N PF15862.5 RLN81300.1 - 9.3e-05 22.2 7.0 0.00014 21.6 7.0 1.5 1 0 0 1 1 1 1 Coilin N-terminus RR_TM4-6 PF06459.12 RLN81300.1 - 0.13 12.1 17.1 0.16 11.8 17.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FIST_C PF10442.9 RLN81300.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 FIST C domain GAGA_bind PF06217.12 RLN81300.1 - 0.41 10.9 9.4 0.51 10.6 9.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF913 PF06025.12 RLN81300.1 - 1.9 7.4 4.6 2.4 7.0 4.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 RLN81300.1 - 3.3 5.9 18.1 4 5.6 18.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 RLN81300.1 - 4.1 7.5 35.2 6 6.9 35.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 TAF4 PF05236.14 RLN81300.1 - 4.3 7.0 18.5 6.1 6.5 18.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family IQ PF00612.27 RLN81301.1 - 5.1e-05 22.7 9.9 0.045 13.5 0.4 4.5 4 0 0 4 4 4 2 IQ calmodulin-binding motif Dpy-30 PF05186.13 RLN81301.1 - 0.21 11.3 8.4 0.16 11.7 0.5 3.1 3 0 0 3 3 3 0 Dpy-30 motif WD40 PF00400.32 RLN81302.1 - 2.1e-21 75.8 10.5 6.2e-05 23.7 0.3 9.2 8 0 0 8 8 8 4 WD domain, G-beta repeat EF-hand_1 PF00036.32 RLN81302.1 - 3.8e-20 69.9 14.2 0.00045 19.6 0.6 5.7 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 RLN81302.1 - 6.5e-20 69.3 12.1 5e-05 22.9 1.0 5.7 5 0 0 5 5 5 5 EF-hand domain EF-hand_7 PF13499.6 RLN81302.1 - 2.3e-18 66.4 12.3 7.6e-07 29.5 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 RLN81302.1 - 2.7e-12 45.6 5.7 0.016 14.7 0.0 4.9 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 RLN81302.1 - 2.7e-05 23.9 15.2 0.0087 15.9 0.1 5.5 4 2 2 6 6 6 3 EF-hand domain pair ANAPC4_WD40 PF12894.7 RLN81302.1 - 0.064 13.6 0.1 12 6.3 0.0 3.4 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain MFS_1 PF07690.16 RLN81328.1 - 1.1e-09 37.7 21.1 1.3e-09 37.4 21.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PglZ PF08665.12 RLN81328.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 PglZ domain CTC1 PF15489.6 RLN81329.1 - 0.11 10.0 0.0 0.16 9.4 0.0 1.1 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 p450 PF00067.22 RLN81330.1 - 2.2e-72 244.3 0.0 2.7e-72 244.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 OB_NTP_bind PF07717.16 RLN81331.1 - 1.3e-21 76.7 0.1 4.4e-21 75.0 0.1 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 RLN81331.1 - 6.6e-21 74.6 0.0 6.6e-21 74.6 0.0 3.2 3 1 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 RLN81331.1 - 1.6e-12 47.7 0.0 4e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RLN81331.1 - 5.7e-07 29.5 0.0 1.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RLN81331.1 - 0.00023 21.5 0.0 0.00073 19.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RLN81331.1 - 0.00034 20.4 0.0 0.00092 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 RLN81331.1 - 0.00072 18.7 0.0 0.002 17.3 0.0 1.8 1 1 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 RLN81331.1 - 0.00091 18.6 0.0 0.0026 17.1 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 RLN81331.1 - 0.0012 19.2 0.0 0.0031 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 RLN81331.1 - 0.019 14.9 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain CRF PF00473.17 RLN81331.1 - 0.1 12.7 0.2 0.32 11.1 0.2 1.8 1 0 0 1 1 1 0 Corticotropin-releasing factor family DUF4407 PF14362.6 RLN81332.1 - 0.026 13.9 0.2 0.029 13.8 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3138 PF11336.8 RLN81332.1 - 0.047 12.3 0.0 0.048 12.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Sde2_N_Ubi PF13019.6 RLN81332.1 - 0.06 13.2 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Spc7 PF08317.11 RLN81332.1 - 0.11 11.4 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CtIP_N PF10482.9 RLN81386.1 - 0.015 15.4 4.8 0.015 15.4 4.8 2.4 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Prominin PF05478.11 RLN81386.1 - 0.025 12.6 2.9 0.042 11.8 2.9 1.3 1 0 0 1 1 1 0 Prominin Cor1 PF04803.12 RLN81386.1 - 0.028 14.6 10.8 0.07 13.3 10.8 1.7 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region Ax_dynein_light PF10211.9 RLN81386.1 - 0.66 9.9 23.4 0.01 15.8 15.1 2.3 2 2 0 2 2 2 0 Axonemal dynein light chain Phage_GPO PF05929.11 RLN81386.1 - 1.6 8.3 8.4 0.22 11.1 3.9 1.7 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase IQ PF00612.27 RLN81386.1 - 1.8 8.6 7.6 3 7.9 0.3 3.7 4 0 0 4 4 4 0 IQ calmodulin-binding motif DUF16 PF01519.16 RLN81386.1 - 2 8.9 10.1 0.74 10.3 5.5 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 DASH_Dad1 PF08649.10 RLN81386.1 - 6.4 7.1 8.6 1.1 9.5 1.1 2.8 3 0 0 3 3 3 0 DASH complex subunit Dad1 PIP5K PF01504.18 RLN81387.1 - 1.6e-69 234.2 0.1 3.1e-69 233.3 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase RCR PF12273.8 RLN81387.1 - 0.11 13.2 0.6 0.3 11.7 0.6 1.8 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red PMP1_2 PF08114.11 RLN81387.1 - 0.4 10.4 4.3 4.4 7.1 0.3 2.8 2 0 0 2 2 2 0 ATPase proteolipid family AAA_25 PF13481.6 RLN81420.1 - 0.033 13.8 0.1 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Y_phosphatase PF00102.27 RLN81420.1 - 0.094 12.3 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase AAA_10 PF12846.7 RLN81420.1 - 0.099 11.5 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain KIX_2 PF16987.5 RLN81421.1 - 0.0033 17.4 0.1 0.0076 16.2 0.1 1.5 1 0 0 1 1 1 1 KIX domain Ldh_1_N PF00056.23 RLN81422.1 - 2.8e-32 111.7 0.3 4.9e-32 110.9 0.3 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 RLN81422.1 - 3e-28 98.8 0.1 4.1e-28 98.4 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain PIP5K PF01504.18 RLN81423.1 - 7.1e-58 196.0 0.6 3.7e-49 167.4 0.1 2.3 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase 7TM_GPCR_Srsx PF10320.9 RLN81423.1 - 1.9e-06 27.5 2.3 5.2e-06 26.0 2.3 1.7 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_2 PF00002.24 RLN81423.1 - 0.00084 18.7 1.4 0.00084 18.7 1.4 2.0 2 1 1 3 3 3 1 7 transmembrane receptor (Secretin family) Ferric_reduct PF01794.19 RLN81423.1 - 0.089 12.9 2.1 0.24 11.5 2.1 1.7 1 0 0 1 1 1 0 Ferric reductase like transmembrane component Dicty_CAR PF05462.11 RLN81423.1 - 3.5 6.7 12.6 0.014 14.6 1.7 2.3 3 0 0 3 3 3 0 Slime mold cyclic AMP receptor Transp_cyt_pur PF02133.15 RLN81424.1 - 2.9e-40 138.4 39.2 3.5e-40 138.1 39.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Phage_Coat_Gp8 PF05371.12 RLN81424.1 - 4.3 7.2 8.5 18 5.2 0.1 3.3 2 1 1 3 3 3 0 Phage major coat protein, Gp8 zf-PARP PF00645.18 RLN81425.1 - 1.2e-05 26.1 0.3 1.6e-05 25.7 0.1 1.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region MOZ_SAS PF01853.18 RLN81426.1 - 2.3e-59 200.1 0.2 3.2e-59 199.6 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 RLN81426.1 - 4.9e-09 35.7 0.1 9.4e-09 34.8 0.1 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain FCP1_C PF09309.10 RLN81426.1 - 0.23 11.3 12.2 0.76 9.6 12.7 1.6 2 0 0 2 2 2 0 FCP1, C-terminal CNDH2_M PF16869.5 RLN81426.1 - 3.3 8.4 8.0 5.5 7.7 8.0 1.2 1 0 0 1 1 1 0 PF16858 DUF3712 PF12505.8 RLN81427.1 - 2.2e-36 124.9 1.6 7.7e-15 55.3 0.0 4.3 4 0 0 4 4 4 3 Protein of unknown function (DUF3712) LEA_2 PF03168.13 RLN81427.1 - 1.4e-06 28.8 0.0 2.8 8.5 0.0 5.1 6 0 0 6 6 6 3 Late embryogenesis abundant protein TraQ PF09679.10 RLN81427.1 - 0.12 12.4 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) Transp_cyt_pur PF02133.15 RLN81428.1 - 1.6e-39 136.0 34.7 2e-39 135.6 34.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4525 PF15027.6 RLN81428.1 - 0.19 11.4 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) Pkinase_Tyr PF07714.17 RLN81429.1 - 2.8e-21 76.0 0.0 6.7e-09 35.4 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase LRR_8 PF13855.6 RLN81429.1 - 8.7e-12 44.6 10.6 2.6e-07 30.3 2.9 3.4 1 1 3 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 RLN81429.1 - 1.8e-06 28.2 13.7 0.041 14.3 0.6 4.0 3 1 0 3 3 3 3 Leucine Rich repeats (2 copies) Pkinase PF00069.25 RLN81429.1 - 0.0031 16.9 0.0 16 4.8 0.0 3.5 3 1 0 3 3 3 2 Protein kinase domain LRR_9 PF14580.6 RLN81429.1 - 0.25 10.9 0.4 1.6 8.2 0.4 1.9 1 1 1 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.33 RLN81429.1 - 3.6 8.5 5.5 2.8e+02 2.8 0.1 4.5 3 1 0 3 3 3 0 Leucine Rich Repeat Asp PF00026.23 RLN81430.1 - 4e-22 79.1 0.0 2.3e-14 53.5 0.0 3.2 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 RLN81430.1 - 2.4e-09 37.7 0.2 0.00012 22.4 0.0 3.1 3 0 0 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 RLN81430.1 - 0.0047 16.7 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 RLN81430.1 - 0.0083 16.8 0.0 0.44 11.2 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease PLAC8 PF04749.17 RLN81431.1 - 9.8e-06 26.5 5.9 1.3e-05 26.1 5.9 1.2 1 0 0 1 1 1 1 PLAC8 family EVC2_like PF12297.8 RLN81431.1 - 0.093 11.4 0.3 0.12 11.1 0.3 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein SDF PF00375.18 RLN81432.1 - 1.3e-31 110.0 17.2 9.1e-31 107.2 17.2 1.9 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family Activator_LAG-3 PF11498.8 RLN81432.1 - 0.074 12.0 9.2 0.11 11.4 9.2 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 E_Pc_C PF06752.12 RLN81432.1 - 5 7.2 17.4 9.2 6.3 17.4 1.3 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus EzrA PF06160.12 RLN81465.1 - 0.0022 16.3 0.4 0.0022 16.3 0.4 1.5 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA CxC7 PF18866.1 RLN81465.1 - 0.025 14.7 0.4 0.05 13.7 0.4 1.4 1 0 0 1 1 1 0 CxC7 like cysteine cluster associated with KDZ transposases DUF2205 PF10224.9 RLN81465.1 - 0.51 10.4 2.7 0.99 9.4 0.6 2.3 1 1 1 2 2 2 0 Short coiled-coil protein Siah-Interact_N PF09032.11 RLN81465.1 - 0.58 10.5 3.1 0.91 9.9 1.8 2.1 1 1 1 2 2 2 0 Siah interacting protein, N terminal Myb_DNA-binding PF00249.31 RLN81489.1 - 0.0042 17.2 0.1 0.0079 16.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2559 PF10832.8 RLN81489.1 - 0.054 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2559) Glyco_transf_8 PF01501.20 RLN81491.1 - 1.2e-05 25.0 0.0 9.6e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 RLN81491.1 - 0.023 14.0 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative NUC173 PF08161.12 RLN81492.1 - 4e-56 189.9 0.1 4e-56 189.9 0.1 3.5 4 0 0 4 4 4 1 NUC173 domain Vac14_Fab1_bd PF12755.7 RLN81492.1 - 0.033 14.8 0.0 42 4.8 0.0 4.9 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region TAFH PF07531.14 RLN81492.1 - 3.3 7.9 5.2 2.6 8.2 0.5 3.1 3 0 0 3 3 3 0 NHR1 homology to TAF Aldedh PF00171.22 RLN81493.1 - 2.9e-185 616.2 0.0 3.3e-185 616.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PrgU PF09627.10 RLN81493.1 - 0.09 12.8 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 PrgU-like protein Aldedh PF00171.22 RLN81494.1 - 3.9e-14 52.0 0.1 4.2e-14 51.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MMS19_C PF12460.8 RLN81495.1 - 4.2e-83 279.8 0.7 4.2e-83 279.8 0.7 3.2 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 RLN81495.1 - 1.2e-81 274.1 5.9 4.1e-81 272.4 1.9 3.4 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II RICTOR_N PF14664.6 RLN81495.1 - 0.0091 15.0 0.2 0.13 11.2 0.2 2.4 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term Cnd1 PF12717.7 RLN81495.1 - 0.013 15.5 0.1 1.8 8.6 0.0 3.6 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RLN81495.1 - 0.014 15.6 0.1 0.014 15.6 0.1 7.5 9 0 0 9 9 9 0 HEAT repeat HEAT_EZ PF13513.6 RLN81495.1 - 0.18 12.4 26.5 2.8 8.5 0.0 8.3 8 1 1 9 9 9 0 HEAT-like repeat FKBP_N PF01346.18 RLN81496.1 - 8.8 7.4 10.4 3.6 8.6 2.2 2.9 2 1 1 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase RRF PF01765.19 RLN81497.1 - 4.4e-43 147.0 5.7 6.3e-43 146.5 5.7 1.2 1 0 0 1 1 1 1 Ribosome recycling factor SpecificRecomb PF10136.9 RLN81497.1 - 0.021 13.2 1.8 0.026 12.8 1.8 1.1 1 0 0 1 1 1 0 Site-specific recombinase DUF87 PF01935.17 RLN81497.1 - 0.086 12.9 1.3 0.13 12.3 1.3 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain DUF3829 PF12889.7 RLN81497.1 - 0.13 11.7 8.5 0.28 10.6 8.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF1682 PF07946.14 RLN81497.1 - 0.18 11.0 7.2 0.24 10.5 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF883 PF05957.13 RLN81497.1 - 0.23 12.1 9.3 0.042 14.4 4.5 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Lectin_N PF03954.14 RLN81497.1 - 0.35 10.6 3.1 0.72 9.6 2.8 1.6 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain HisKA_3 PF07730.13 RLN81497.1 - 0.69 10.5 9.0 73 4.0 0.0 3.4 2 1 0 2 2 2 0 Histidine kinase PBP1_TM PF14812.6 RLN81497.1 - 2.8 8.4 7.3 15 6.1 3.3 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YtxH PF12732.7 RLN81497.1 - 3.3 8.3 15.9 0.26 11.9 8.9 2.5 2 1 0 2 2 2 0 YtxH-like protein DUF2262 PF10020.9 RLN81497.1 - 3.8 7.9 6.2 0.64 10.4 2.7 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2262) DUF948 PF06103.11 RLN81497.1 - 3.8 7.8 7.7 5.7 7.3 4.9 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FYDLN_acid PF09538.10 RLN81497.1 - 5.8 7.6 13.9 9.3 7.0 5.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) TMPIT PF07851.13 RLN81497.1 - 8 5.6 6.3 12 5.0 6.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein WD40 PF00400.32 RLN81498.1 - 1.9e-40 136.1 24.7 2.2e-08 34.6 0.9 7.1 7 0 0 7 7 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN81498.1 - 1.8e-12 47.4 0.9 0.0074 16.6 0.0 5.7 2 1 3 5 5 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN81498.1 - 6.6e-05 22.0 3.4 1.2 8.1 0.0 4.3 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RLN81498.1 - 0.0004 19.2 1.2 0.61 8.7 0.1 4.6 3 1 3 6 6 6 1 Nucleoporin Nup120/160 Med3 PF11593.8 RLN81498.1 - 0.0063 15.8 2.5 0.0063 15.8 2.5 1.7 2 0 0 2 2 2 1 Mediator complex subunit 3 fungal MSA-2c PF12238.8 RLN81498.1 - 0.035 14.1 0.9 0.085 12.9 0.9 1.7 1 0 0 1 1 1 0 Merozoite surface antigen 2c FSA_C PF10479.9 RLN81498.1 - 0.093 10.8 3.1 0.15 10.2 3.1 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Ribosomal_L9_N PF01281.19 RLN81498.1 - 0.13 11.8 0.1 3.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L9, N-terminal domain Rab5-bind PF09311.11 RLN81498.1 - 0.15 11.4 8.0 0.22 10.9 8.0 1.1 1 0 0 1 1 1 0 Rabaptin-like protein YabA PF06156.13 RLN81498.1 - 0.16 12.6 1.1 1.7 9.3 0.2 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Fib_alpha PF08702.10 RLN81498.1 - 0.23 11.6 3.5 0.42 10.8 3.5 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Cortex-I_coil PF09304.10 RLN81498.1 - 0.56 10.4 7.8 1.1 9.5 7.8 1.5 1 0 0 1 1 1 0 Cortexillin I, coiled coil DUF4200 PF13863.6 RLN81498.1 - 1.2 9.5 12.5 0.5 10.8 9.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) GPS2_interact PF15784.5 RLN81498.1 - 2.3 8.7 4.9 3.8 8.0 3.7 2.0 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3450 PF11932.8 RLN81498.1 - 6.2 6.0 12.3 0.27 10.5 5.5 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF572 PF04502.13 RLN81498.1 - 6.6 6.3 7.3 11 5.6 7.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Cep57_CLD_2 PF14197.6 RLN81498.1 - 7.6 6.7 8.3 12 6.1 3.9 2.7 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Trypsin_2 PF13365.6 RLN81499.1 - 2.7e-10 41.4 0.1 1.7e-09 38.7 0.0 2.0 2 0 0 2 2 2 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.13 RLN81499.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Anoctamin PF04547.12 RLN81529.1 - 2.6e-71 240.8 10.3 3.2e-71 240.5 10.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel RSN1_7TM PF02714.15 RLN81529.1 - 0.0066 15.8 1.7 0.013 14.8 1.7 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate DUF2207 PF09972.9 RLN81529.1 - 0.0073 15.1 0.8 0.42 9.3 0.0 2.2 2 0 0 2 2 2 2 Predicted membrane protein (DUF2207) DUF2427 PF10348.9 RLN81529.1 - 0.05 13.4 0.6 1 9.2 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Abhydrolase_9_N PF15420.6 RLN81529.1 - 0.14 12.2 0.2 0.75 9.8 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF4091 PF13320.6 RLN81530.1 - 1.1e-17 63.9 0.3 1.6e-17 63.4 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4091) Tudor-knot PF11717.8 RLN81531.1 - 3.7e-06 26.7 0.0 7.6e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Apidaecin PF00807.17 RLN81531.1 - 0.17 12.0 1.7 0.27 11.4 0.2 2.1 2 0 0 2 2 2 0 Apidaecin Ran_BP1 PF00638.18 RLN81532.1 - 0.00029 21.1 0.0 0.00058 20.1 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain SPX PF03105.19 RLN81532.1 - 1.5 8.7 10.9 2.4 8.0 10.8 1.4 1 1 0 1 1 1 0 SPX domain ABC_tran PF00005.27 RLN81533.1 - 7.9e-18 65.3 1.6 1.1e-17 64.8 0.0 2.1 2 1 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.12 RLN81533.1 - 6.1e-05 22.4 0.7 0.0008 18.7 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin AAA_16 PF13191.6 RLN81533.1 - 0.0011 19.4 0.0 0.0011 19.4 0.0 2.6 2 2 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 RLN81533.1 - 0.003 16.8 0.0 0.0059 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 RLN81533.1 - 0.0042 16.8 0.1 0.014 15.2 0.1 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN81533.1 - 0.0046 17.2 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.20 RLN81533.1 - 0.0055 15.9 0.5 0.013 14.7 0.0 1.7 2 0 0 2 2 2 1 G-protein alpha subunit RsgA_GTPase PF03193.16 RLN81533.1 - 0.019 14.8 0.1 0.046 13.6 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase Ploopntkinase3 PF18751.1 RLN81533.1 - 0.03 14.2 0.0 0.099 12.6 0.0 1.8 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Mg_chelatase PF01078.21 RLN81533.1 - 0.031 13.6 0.1 3 7.2 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RLN81533.1 - 0.033 14.2 0.1 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) HlyD_D4 PF16572.5 RLN81533.1 - 0.058 13.3 1.3 0.19 11.6 0.6 2.2 1 1 1 2 2 2 0 Long alpha hairpin domain of cation efflux system protein, CusB MMR_HSR1 PF01926.23 RLN81533.1 - 0.07 13.2 0.2 0.25 11.4 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 RLN81533.1 - 0.16 12.4 1.6 0.99 9.8 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 RLN81533.1 - 0.17 12.3 1.8 0.7 10.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain PIN_3 PF13470.6 RLN81533.1 - 0.43 11.4 7.1 0.27 12.0 3.4 2.4 1 1 1 2 2 2 0 PIN domain SMC_N PF02463.19 RLN81533.1 - 0.51 9.7 4.9 2 7.8 0.8 3.1 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain RRM_1 PF00076.22 RLN81563.1 - 1e-08 34.9 0.1 1.3e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.11 RLN81563.1 - 2.2e-06 26.8 0.0 4.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) YkuD PF03734.14 RLN81563.1 - 0.15 12.5 0.0 0.84 10.1 0.0 2.1 2 0 0 2 2 2 0 L,D-transpeptidase catalytic domain Pkinase_Tyr PF07714.17 RLN81597.1 - 9.4e-55 185.7 0.0 2.8e-42 144.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN81597.1 - 1.2e-47 162.5 0.0 1.2e-36 126.5 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Ank_2 PF12796.7 RLN81597.1 - 2.2e-31 108.3 2.8 3.3e-13 50.0 0.3 4.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN81597.1 - 5.9e-28 96.9 0.2 2.9e-08 34.1 0.1 5.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN81597.1 - 1.7e-19 69.3 6.1 5e-05 23.6 0.0 6.0 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 RLN81597.1 - 4.8e-17 61.8 4.0 1.5e-05 25.2 0.2 5.2 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN81597.1 - 1.1e-16 59.2 0.4 0.069 13.7 0.0 7.0 6 0 0 6 6 6 4 Ankyrin repeat Arm PF00514.23 RLN81597.1 - 1e-12 47.6 11.8 0.0082 16.2 0.0 8.2 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN81597.1 - 1.5e-06 28.5 20.1 0.021 15.2 4.9 5.8 3 1 3 6 6 5 4 HEAT repeats HEAT_EZ PF13513.6 RLN81597.1 - 0.00038 20.9 16.1 1 10.0 0.1 6.0 4 1 1 5 5 5 3 HEAT-like repeat HEAT PF02985.22 RLN81597.1 - 0.01 16.0 6.7 18 5.9 0.0 6.2 5 0 0 5 5 4 0 HEAT repeat MoaE PF02391.17 RLN81597.1 - 0.088 13.1 0.0 51 4.2 0.0 3.7 3 0 0 3 3 3 0 MoaE protein Pkinase_fungal PF17667.1 RLN81597.1 - 0.13 11.0 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase TPR_16 PF13432.6 RLN81597.1 - 1.1 10.0 4.3 1.5 9.6 0.1 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat NHR2 PF08788.11 RLN81622.1 - 0.035 13.9 0.7 0.12 12.1 0.7 1.9 1 0 0 1 1 1 0 NHR2 domain like GAS PF13851.6 RLN81622.1 - 0.2 11.0 18.5 3.2 7.1 13.8 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding LigT_PEase PF02834.16 RLN81623.1 - 0.0054 16.9 0.0 0.037 14.2 0.0 2.5 1 0 0 1 1 1 1 LigT like Phosphoesterase DUF5347 PF17282.2 RLN81623.1 - 1.3 9.4 10.4 7.8 6.9 0.3 4.2 3 0 0 3 3 3 0 Family of unknown function (DUF5347) CDT1_C PF16679.5 RLN81624.1 - 0.016 15.6 0.6 0.22 12.0 0.1 2.5 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain SNF2_N PF00176.23 RLN81646.1 - 1.2e-71 241.3 0.3 3e-71 240.0 0.3 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 RLN81646.1 - 2.8e-37 127.2 0.7 1.1e-36 125.4 0.7 2.1 1 0 0 1 1 1 1 SLIDE Helicase_C PF00271.31 RLN81646.1 - 2.3e-21 76.2 0.0 1.2e-20 73.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN81646.1 - 9.7e-07 28.9 0.0 6.7e-06 26.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HAND PF09110.11 RLN81646.1 - 0.0011 19.7 7.2 0.0011 19.7 7.2 2.5 2 0 0 2 2 2 1 HAND AAA_14 PF13173.6 RLN81646.1 - 0.02 15.0 0.0 0.093 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 RLN81646.1 - 0.032 14.1 0.2 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TPR_1 PF00515.28 RLN81647.1 - 5.4e-09 35.5 2.3 0.0012 18.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN81647.1 - 1.3e-07 31.1 3.3 0.0079 16.2 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN81647.1 - 9.3e-06 25.2 0.2 0.0032 17.1 0.1 2.5 1 1 1 2 2 2 2 TPR repeat TPR_12 PF13424.6 RLN81647.1 - 0.00037 20.7 4.4 0.024 14.9 0.9 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN81647.1 - 0.0022 18.1 0.0 1.3 9.4 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN81647.1 - 0.043 14.3 0.2 0.043 14.3 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN81647.1 - 0.078 13.6 1.6 0.11 13.1 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 RLN81647.1 - 0.083 13.3 0.4 0.45 11.0 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_6 PF13516.6 RLN81649.1 - 1.5e-06 27.7 11.8 0.68 10.1 0.0 6.6 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 RLN81649.1 - 9.5e-06 25.9 8.3 1.7 9.2 0.3 5.9 3 2 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN81649.1 - 2.6e-05 23.9 10.6 0.53 10.1 0.1 5.9 4 2 3 7 7 7 4 Leucine rich repeat SR-25 PF10500.9 RLN81649.1 - 0.2 11.2 2.9 0.33 10.5 2.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LRR_1 PF00560.33 RLN81649.1 - 0.36 11.6 13.0 3.8 8.4 0.1 5.5 7 0 0 7 7 7 0 Leucine Rich Repeat SPRY PF00622.28 RLN81650.1 - 1.7e-17 63.6 0.0 4.6e-17 62.2 0.0 1.7 2 0 0 2 2 2 1 SPRY domain Neuralized PF07177.12 RLN81650.1 - 0.025 14.6 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Neuralized Atg8 PF02991.16 RLN81650.1 - 0.083 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like PXA PF02194.15 RLN81652.1 - 0.097 12.6 0.6 0.11 12.5 0.6 1.2 1 0 0 1 1 1 0 PXA domain EF-hand_1 PF00036.32 RLN81654.1 - 2.5e-12 45.4 0.1 5e-05 22.6 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN81654.1 - 3.4e-11 42.1 0.6 0.00014 21.5 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 RLN81654.1 - 2.6e-07 29.8 0.1 0.017 14.6 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RLN81654.1 - 3.3e-06 27.4 0.1 0.071 13.6 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 RLN81654.1 - 0.027 14.3 0.3 0.44 10.4 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain pair Flg_bb_rod PF00460.20 RLN81655.1 - 0.0038 17.1 0.7 0.0077 16.1 0.7 1.5 1 0 0 1 1 1 1 Flagella basal body rod protein TPR_10 PF13374.6 RLN81655.1 - 0.098 12.6 0.3 0.94 9.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat CDC45 PF02724.14 RLN81656.1 - 0.48 8.7 9.1 0.68 8.1 9.1 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 RLN81656.1 - 0.52 10.4 23.3 1.2 9.2 23.3 1.7 1 1 0 1 1 1 0 YL1 nuclear protein RRN3 PF05327.11 RLN81656.1 - 1.7 7.1 5.6 2.3 6.7 5.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Zip PF02535.22 RLN81689.1 - 2.6e-14 53.2 13.7 7.9e-14 51.6 13.7 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.22 RLN81690.1 - 0.0015 17.8 1.3 0.003 16.8 1.3 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter GTP_EFTU PF00009.27 RLN81691.1 - 5.1e-22 78.4 0.1 7.9e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 RLN81691.1 - 0.0033 17.8 0.2 0.01 16.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RLN81691.1 - 0.0051 16.9 0.0 0.018 15.1 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF4246 PF14033.6 RLN81694.1 - 3.6e-16 59.3 0.1 7.4e-16 58.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) PX PF00787.24 RLN81723.1 - 1.4e-06 28.3 0.1 2.5e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 PX domain CENP-H PF05837.12 RLN81723.1 - 0.029 14.8 8.3 0.052 13.9 8.3 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF3450 PF11932.8 RLN81723.1 - 0.073 12.4 8.4 0.11 11.7 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) YabA PF06156.13 RLN81723.1 - 0.68 10.6 3.4 2 9.1 3.2 1.9 1 1 0 1 1 1 0 Initiation control protein YabA Fib_alpha PF08702.10 RLN81723.1 - 1.2 9.3 5.2 2.6 8.2 4.9 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF737 PF05300.11 RLN81723.1 - 1.8 8.8 9.1 3.1 8.1 9.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Zwint PF15556.6 RLN81723.1 - 1.9 8.0 12.4 6.3 6.2 0.0 2.2 1 1 1 2 2 2 0 ZW10 interactor DUF2381 PF09544.10 RLN81723.1 - 7.9 5.9 9.8 6.1 6.3 4.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2381) Dynein_C PF18199.1 RLN81724.1 - 9.9e-98 327.1 0.0 1.7e-97 326.4 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 RLN81724.1 - 1.2e-90 302.5 0.2 1.5e-89 298.9 0.8 2.1 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 RLN81724.1 - 1.4e-56 190.9 0.0 2.5e-56 190.0 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RLN81724.1 - 4.3e-44 149.4 0.0 2.5e-40 137.3 0.0 2.6 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain Trans_reg_C PF00486.28 RLN81724.1 - 0.01 15.9 0.1 3.3 7.9 0.1 2.8 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal MT PF12777.7 RLN81724.1 - 0.06 12.4 0.0 0.13 11.2 0.0 1.6 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor Sun2_CC2 PF18580.1 RLN81724.1 - 0.12 12.6 0.3 0.32 11.3 0.3 1.7 1 0 0 1 1 1 0 SUN2 coiled coil domain 2 Tannase PF07519.11 RLN81760.1 - 2.1e-116 389.6 0.0 2.6e-116 389.3 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 RLN81760.1 - 0.00066 19.2 0.0 0.84 9.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 RLN81760.1 - 0.058 13.0 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF4209 PF13910.6 RLN81792.1 - 1.4e-19 70.1 0.5 3.7e-16 59.1 0.6 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4209) SEEEED PF14797.6 RLN81793.1 - 0.02 15.0 3.3 0.027 14.6 3.3 1.2 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Trypan_PARP PF05887.11 RLN81793.1 - 0.031 14.3 8.4 0.06 13.3 8.4 1.5 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Surp PF01805.20 RLN81887.1 - 1.5e-05 24.9 0.0 2.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Surp module FH2 PF02181.23 RLN81888.1 - 2.3e-85 287.0 0.9 2.3e-85 287.0 0.9 2.6 3 1 0 3 3 3 1 Formin Homology 2 Domain CCDC53 PF10152.9 RLN81888.1 - 5.6e-68 228.2 37.4 4.4e-08 33.7 0.1 10.7 11 0 0 11 11 11 8 Subunit CCDC53 of WASH complex Drf_FH3 PF06367.16 RLN81888.1 - 8.2e-20 71.2 7.3 1.1e-09 38.2 0.8 2.8 3 0 0 3 3 3 2 Diaphanous FH3 Domain Drf_GBD PF06371.13 RLN81888.1 - 1.6e-13 50.7 0.0 7.6e-12 45.2 0.0 2.7 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain HSBP1 PF06825.12 RLN81888.1 - 0.17 11.8 6.5 1 9.3 0.6 2.7 2 0 0 2 2 2 0 Heat shock factor binding protein 1 TRAPP PF04051.16 RLN81950.1 - 6.6e-33 113.5 0.0 8.2e-33 113.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Beach PF02138.18 RLN81951.1 - 7.3e-113 376.5 0.0 1.2e-112 375.8 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 RLN81951.1 - 4.1e-12 46.4 12.0 0.00026 21.7 0.0 5.5 5 1 1 6 6 6 3 WD domain, G-beta repeat PH_BEACH PF14844.6 RLN81951.1 - 5.3e-09 36.1 0.1 7.7e-07 29.1 0.0 3.2 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH ANAPC4_WD40 PF12894.7 RLN81951.1 - 1.9e-07 31.3 0.0 1.7 9.0 0.0 5.0 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain GRAM PF02893.20 RLN81951.1 - 0.002 18.0 0.0 0.0068 16.3 0.0 1.8 2 0 0 2 2 2 1 GRAM domain Ge1_WD40 PF16529.5 RLN81951.1 - 0.058 12.3 0.0 1.8 7.4 0.0 2.5 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PH_TFIIH PF08567.11 RLN81951.1 - 0.06 13.7 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain LSM PF01423.22 RLN81952.1 - 3.9e-15 55.3 0.0 5.1e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RLN81952.1 - 5.8e-05 23.2 0.0 7.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DEAD PF00270.29 RLN81953.1 - 2e-48 164.4 0.0 1.3e-47 161.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN81953.1 - 5.1e-26 91.2 0.0 1.9e-25 89.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN81953.1 - 1.4e-05 25.2 0.0 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SAPS PF04499.15 RLN81954.1 - 1.1e-19 70.6 12.1 7.3e-15 54.7 0.0 4.6 3 1 1 4 4 4 4 SIT4 phosphatase-associated protein DUF966 PF06136.13 RLN81954.1 - 8 6.1 8.1 19 4.8 7.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Keratin_2_head PF16208.5 RLN81955.1 - 0.0084 16.3 19.2 0.01 16.0 19.2 1.1 1 0 0 1 1 1 1 Keratin type II head Exo_endo_phos PF03372.23 RLN81956.1 - 3.2e-05 23.6 0.0 8.6e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NHL PF01436.21 RLN81957.1 - 4.1e-12 45.5 0.6 1.8e-05 24.5 0.0 4.8 5 0 0 5 5 5 3 NHL repeat Phytase-like PF13449.6 RLN81957.1 - 0.00031 20.8 0.0 0.00058 19.9 0.0 1.3 1 0 0 1 1 1 1 Esterase-like activity of phytase DUF5128 PF17170.4 RLN81957.1 - 0.0004 19.6 0.0 0.019 14.2 0.0 2.1 2 0 0 2 2 2 2 6-bladed beta-propeller SGL PF08450.12 RLN81957.1 - 0.022 14.4 0.0 0.39 10.2 0.0 2.1 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region TRL PF13146.6 RLN81958.1 - 0.00061 20.0 0.1 0.00099 19.3 0.1 1.3 1 0 0 1 1 1 1 TRL-like protein family AA_kinase PF00696.28 RLN81959.1 - 2.6e-36 125.4 0.1 3.8e-36 124.9 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family PTS_IIA PF02255.16 RLN81959.1 - 0.0014 18.6 0.1 0.0028 17.7 0.1 1.4 1 0 0 1 1 1 1 PTS system, Lactose/Cellobiose specific IIA subunit Autotransporter PF03797.19 RLN81959.1 - 0.046 13.4 0.6 0.075 12.7 0.6 1.3 1 0 0 1 1 1 0 Autotransporter beta-domain Nop16 PF09420.10 RLN81959.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 MFS_1 PF07690.16 RLN81960.1 - 1.4e-23 83.4 24.8 8.4e-18 64.4 8.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN81960.1 - 2.1e-07 30.2 2.0 2.1e-07 30.2 2.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 RLN81960.1 - 0.0008 18.4 0.0 0.0036 16.2 0.0 2.2 1 1 0 1 1 1 1 MFS_1 like family Arm PF00514.23 RLN81961.1 - 0.00088 19.2 0.1 0.012 15.7 0.0 2.7 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat zf-C2H2_3 PF13878.6 RLN81962.1 - 9.7e-14 50.9 0.2 1.4e-13 50.5 0.2 1.2 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Arm PF00514.23 RLN81963.1 - 4.8e-96 312.2 45.1 1.7e-06 27.9 0.1 22.5 22 0 0 22 22 22 21 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN81963.1 - 1.8e-23 82.6 51.5 0.0023 18.4 1.9 14.3 10 3 5 15 15 15 10 HEAT-like repeat HEAT PF02985.22 RLN81963.1 - 2.5e-15 55.3 28.8 6.7 7.3 0.0 17.4 19 0 0 19 19 19 2 HEAT repeat Atx10homo_assoc PF09759.9 RLN81963.1 - 6.3e-13 48.6 10.8 0.36 10.9 0.0 9.0 5 3 2 9 9 9 4 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 RLN81963.1 - 6.5e-10 39.3 71.1 0.026 14.9 4.2 10.3 3 2 6 12 12 12 9 HEAT repeats Arm_2 PF04826.13 RLN81963.1 - 1.5e-09 37.7 0.0 1.2 8.6 0.0 7.3 5 2 2 7 7 7 1 Armadillo-like DUF1654 PF07867.11 RLN81963.1 - 2.1e-07 30.5 5.4 4.6 7.1 0.0 8.4 4 2 6 10 10 10 2 Protein of unknown function (DUF1654) UNC45-central PF11701.8 RLN81963.1 - 1.6e-05 24.9 0.0 2.8 7.9 0.0 6.2 7 2 0 8 8 8 1 Myosin-binding striated muscle assembly central Arylsulfotran_N PF17425.2 RLN81963.1 - 3.9e-05 23.6 0.0 1.9e+02 2.1 0.0 9.2 13 0 0 13 13 13 0 Arylsulfotransferase Ig-like domain DUF397 PF04149.12 RLN81963.1 - 0.00046 20.2 14.7 0.65 10.1 0.0 6.4 7 0 0 7 7 6 3 Domain of unknown function (DUF397) DUF4800 PF16057.5 RLN81963.1 - 0.0014 17.9 0.0 1.5 8.1 0.0 4.3 6 1 0 6 6 6 1 Domain of unknown function (DUF4800) Pico_P2B PF01552.17 RLN81963.1 - 0.025 14.7 0.0 22 5.3 0.0 5.7 8 1 0 8 8 5 0 Picornavirus 2B protein DUF4992 PF16383.5 RLN81963.1 - 0.064 12.8 0.7 2.4 7.7 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function DUF503 PF04456.12 RLN81963.1 - 0.41 10.5 1.6 32 4.5 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF503) RNA_pol_Rpb2_4 PF04566.13 RLN81963.1 - 1.5 9.2 7.2 1.3e+02 3.0 0.1 5.7 6 0 0 6 6 5 0 RNA polymerase Rpb2, domain 4 HEAT_PBS PF03130.16 RLN81963.1 - 6.6 7.7 80.7 1.5 9.7 0.1 19.0 21 0 0 21 21 20 0 PBS lyase HEAT-like repeat MRG PF05712.13 RLN81970.1 - 4.4e-41 140.4 1.7 7.6e-33 113.5 0.0 3.4 3 0 0 3 3 3 2 MRG Tudor-knot PF11717.8 RLN81970.1 - 1.5e-08 34.4 0.2 3.5e-08 33.2 0.2 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain ABC_tran PF00005.27 RLN81971.1 - 2.6e-07 31.2 0.0 4.9e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter PDR_CDR PF06422.12 RLN81971.1 - 1.6e-06 27.9 0.0 2.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 CDR ABC transporter PDR_assoc PF08370.11 RLN81971.1 - 0.022 14.5 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Plant PDR ABC transporter associated TPR_1 PF00515.28 RLN81972.1 - 4.8e-25 86.3 8.9 0.0011 18.7 1.3 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat DnaJ PF00226.31 RLN81972.1 - 3.1e-21 75.2 0.8 6.6e-21 74.2 0.8 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 RLN81972.1 - 9.7e-20 69.0 13.1 0.0023 17.9 0.1 8.0 8 0 0 8 8 7 4 Tetratricopeptide repeat Sacchrp_dh_NADP PF03435.18 RLN81972.1 - 3.2e-14 53.3 0.1 3.2e-14 53.3 0.1 2.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TPR_19 PF14559.6 RLN81972.1 - 1.8e-12 47.6 17.3 1.1e-05 25.8 0.5 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN81972.1 - 3.4e-08 33.6 10.7 0.61 11.1 0.1 7.5 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN81972.1 - 7.6e-08 32.5 17.7 0.038 14.3 4.9 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN81972.1 - 9.6e-07 28.5 7.2 6.9 7.2 0.0 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN81972.1 - 2e-05 24.3 15.0 1.4 9.1 0.2 6.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN81972.1 - 3.1e-05 23.6 7.0 0.0095 15.6 0.2 5.0 5 1 0 5 5 5 2 TPR repeat MIT PF04212.18 RLN81972.1 - 7.1e-05 22.8 12.2 0.00051 20.1 0.9 4.1 3 1 1 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 RLN81972.1 - 0.0011 19.5 9.1 0.18 12.5 0.1 6.0 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN81972.1 - 0.0011 19.1 3.1 0.0011 19.1 3.1 4.2 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN81972.1 - 0.002 18.4 0.7 0.32 11.5 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN81972.1 - 0.0028 17.5 9.9 0.11 12.4 0.1 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN81972.1 - 0.0069 17.0 22.8 0.019 15.6 1.9 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat Cyclin_C_2 PF16899.5 RLN81972.1 - 0.017 15.5 2.1 0.14 12.5 0.2 2.9 2 1 1 3 3 3 0 Cyclin C-terminal domain DUF3856 PF12968.7 RLN81972.1 - 0.031 14.3 5.4 0.054 13.6 1.0 3.5 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 RLN81972.1 - 0.061 13.5 10.1 11 6.3 6.6 4.2 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 RLN81972.1 - 0.11 12.2 6.0 0.68 9.6 0.3 3.6 2 1 1 3 3 3 0 26S proteasome subunit RPN7 SHNi-TPR PF10516.9 RLN81972.1 - 2.4 7.7 5.4 28 4.3 0.1 3.7 3 0 0 3 3 3 0 SHNi-TPR Fis1_TPR_C PF14853.6 RLN81972.1 - 9 6.5 6.9 46 4.2 0.6 4.0 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat DSPc PF00782.20 RLN81973.1 - 1.5e-16 60.4 0.0 1.8e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RLN81973.1 - 0.0065 16.6 0.0 0.0096 16.1 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 RLN81973.1 - 0.016 14.9 0.1 0.054 13.2 0.0 1.8 1 1 1 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.12 RLN81973.1 - 0.022 15.0 0.0 0.035 14.4 0.0 1.2 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 RLN81973.1 - 0.056 13.0 0.1 0.14 11.7 0.1 1.7 1 1 0 1 1 1 0 Protein-tyrosine phosphatase Rhodanese PF00581.20 RLN81973.1 - 0.11 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Rhodanese-like domain IFT43 PF15305.6 RLN81974.1 - 1.9e-21 76.7 12.6 8.7e-18 64.8 1.4 2.5 2 1 1 3 3 3 2 Intraflagellar transport protein 43 DUF866 PF05907.13 RLN81975.1 - 3.9e-38 130.8 0.0 4.3e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) AAA_25 PF13481.6 RLN82015.1 - 0.024 14.2 0.0 0.075 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain Y_phosphatase PF00102.27 RLN82015.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase AAA_5 PF07728.14 RLN82015.1 - 0.15 12.1 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Glycos_transf_2 PF00535.26 RLN82016.1 - 1.8e-11 44.2 0.2 2.5e-11 43.7 0.2 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 RLN82016.1 - 1.3e-05 25.2 0.0 1.7e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 HECT_2 PF09814.9 RLN82051.1 - 6.9e-41 140.4 0.0 2.4e-40 138.6 0.0 1.7 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.14 RLN82051.1 - 0.011 16.0 0.1 1.2 9.4 0.0 3.1 3 0 0 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HEAT_2 PF13646.6 RLN82052.1 - 3e-32 110.9 7.9 1.5e-14 54.2 0.4 3.3 2 2 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 RLN82052.1 - 6.2e-22 76.0 1.5 8.7e-05 22.8 0.1 6.0 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 RLN82052.1 - 1.1e-08 34.6 4.0 0.04 14.2 0.0 5.9 5 1 1 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 RLN82052.1 - 0.0016 18.9 2.8 0.41 11.2 0.2 3.4 2 2 1 3 3 3 2 HEAT-like repeat DUF3385 PF11865.8 RLN82052.1 - 0.0023 17.9 0.1 3.7 7.4 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF3385) Ribosomal_L29 PF00831.23 RLN82052.1 - 0.022 14.7 1.3 10 6.2 0.0 3.7 3 1 0 3 3 3 0 Ribosomal L29 protein PX PF00787.24 RLN82053.1 - 1.4e-09 37.9 0.1 2.7e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 PX domain OTU PF02338.19 RLN82053.1 - 0.11 13.0 0.5 1.1 9.7 0.5 2.4 1 1 0 1 1 1 0 OTU-like cysteine protease ubiquitin PF00240.23 RLN82054.1 - 0.00026 20.7 0.0 0.0013 18.5 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_4 PF18036.1 RLN82054.1 - 0.044 13.8 0.0 0.078 13.0 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 RLN82054.1 - 0.05 13.4 0.0 0.076 12.8 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain LSM PF01423.22 RLN82055.1 - 7.4e-17 60.8 0.3 1.8e-16 59.6 0.3 1.7 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RLN82055.1 - 0.011 15.9 0.0 0.032 14.4 0.0 1.8 1 0 0 1 1 1 0 Ataxin 2 SM domain Tail_tube PF10618.9 RLN82055.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Phage tail tube protein Poxvirus_B22R PF04395.12 RLN82055.1 - 0.22 11.0 3.1 0.56 9.7 3.1 1.6 1 0 0 1 1 1 0 Poxvirus B22R protein Ank_2 PF12796.7 RLN82056.1 - 2.4e-37 127.4 11.4 1.5e-16 60.7 0.1 4.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN82056.1 - 2.8e-21 75.3 3.4 5.5e-06 26.6 0.0 5.5 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN82056.1 - 9.3e-21 73.3 3.6 6.3e-05 23.2 0.0 6.1 5 1 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 RLN82056.1 - 3e-20 72.3 0.2 6e-09 36.3 0.0 4.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN82056.1 - 3.9e-18 63.6 0.1 0.0068 16.8 0.0 6.0 5 0 0 5 5 5 5 Ankyrin repeat cNMP_binding PF00027.29 RLN82057.1 - 1e-47 160.1 0.8 2.7e-14 53.0 0.0 5.5 5 0 0 5 5 5 4 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN82057.1 - 8.5e-36 123.4 66.1 8.8e-14 51.3 11.1 4.4 4 0 0 4 4 4 4 Ion transport protein Ion_trans_2 PF07885.16 RLN82057.1 - 0.00088 19.2 20.7 0.76 9.8 0.0 5.5 4 0 0 4 4 4 3 Ion channel MT PF12777.7 RLN82057.1 - 0.054 12.5 1.1 0.091 11.8 1.1 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor Transformer PF06495.11 RLN82057.1 - 0.062 13.4 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Fruit fly transformer protein PAP_assoc PF03828.19 RLN82058.1 - 5.3e-11 42.6 0.0 1.9e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 Cid1 family poly A polymerase DUF3138 PF11336.8 RLN82058.1 - 0.033 12.8 1.2 0.078 11.6 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Prothymosin PF03247.14 RLN82059.1 - 0.0011 19.4 11.7 0.0011 19.4 11.7 2.6 2 0 0 2 2 2 1 Prothymosin/parathymosin family NOA36 PF06524.12 RLN82059.1 - 0.022 14.1 16.1 0.05 12.9 16.1 1.5 1 0 0 1 1 1 0 NOA36 protein HALZ PF02183.18 RLN82059.1 - 0.045 14.0 0.8 0.045 14.0 0.8 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper DNA_pol_phi PF04931.13 RLN82059.1 - 0.27 9.3 22.4 0.54 8.3 22.4 1.5 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 RLN82059.1 - 0.32 9.5 7.6 0.6 8.6 7.6 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PPP4R2 PF09184.11 RLN82059.1 - 0.42 10.2 9.5 1.1 8.8 9.5 1.7 1 0 0 1 1 1 0 PPP4R2 SNARE PF05739.19 RLN82059.1 - 0.59 10.2 1.9 3.1 7.9 0.4 2.5 2 0 0 2 2 2 0 SNARE domain C2 PF00168.30 RLN82094.1 - 1e-05 25.7 0.0 2.7e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 C2 domain C2 PF00168.30 RLN82095.1 - 7.5e-09 35.8 0.0 1.4e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pullulanase_N2 PF17967.1 RLN82095.1 - 0.62 10.9 2.6 1.7 9.5 0.4 2.3 2 0 0 2 2 2 0 Pullulanase N2 domain C2 PF00168.30 RLN82096.1 - 1.5e-10 41.3 0.1 5.3e-10 39.5 0.0 2.0 2 1 0 2 2 2 1 C2 domain Phage_int_SAM_4 PF13495.6 RLN82097.1 - 0.02 15.3 0.5 0.059 13.9 0.1 2.0 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Ank_2 PF12796.7 RLN82098.1 - 5.7e-14 52.5 0.0 0.00052 20.5 0.3 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN82098.1 - 1.1e-13 51.4 5.3 0.0018 18.8 0.1 6.2 3 3 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN82098.1 - 2.9e-10 40.2 3.6 0.19 12.1 0.1 6.5 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN82098.1 - 3.5e-09 36.1 0.1 3.5 8.5 0.0 6.8 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 RLN82098.1 - 0.17 12.4 0.0 44 4.8 0.1 3.8 2 2 0 2 2 2 0 Ankyrin repeat SAM_3 PF18016.1 RLN82098.1 - 0.93 9.3 4.3 26 4.7 0.0 4.3 5 0 0 5 5 5 0 SAM domain (Sterile alpha motif) KH_8 PF17903.1 RLN82099.1 - 2.4e-05 24.3 0.0 6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 RLN82099.1 - 0.0055 16.5 0.1 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 KH domain Foie-gras_1 PF11817.8 RLN82100.1 - 3.9e-25 88.9 0.1 6.9e-25 88.1 0.1 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun-like PF12742.7 RLN82100.1 - 0.033 14.2 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking TRAPPC10 PF12584.8 RLN82100.1 - 0.038 13.7 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Trafficking protein particle complex subunit 10, TRAPPC10 PP2C PF00481.21 RLN82133.1 - 6.5e-45 153.8 0.1 9.6e-45 153.2 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RLN82133.1 - 0.0008 19.1 0.0 0.0023 17.6 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C LPD22 PF18834.1 RLN82133.1 - 0.15 12.3 0.1 0.15 12.3 0.1 2.3 3 0 0 3 3 3 0 Large polyvalent protein associated domain 22 Flavokinase PF01687.17 RLN82134.1 - 9.5e-32 109.6 0.0 1.2e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Riboflavin kinase EamA PF00892.20 RLN82135.1 - 8.4e-25 87.5 26.2 1.8e-13 50.9 12.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 RLN82135.1 - 2.2e-06 27.2 16.8 0.00011 21.7 1.0 3.0 3 0 0 3 3 3 3 Triose-phosphate Transporter family SLC35F PF06027.12 RLN82135.1 - 1.7e-05 24.5 13.5 0.00019 21.1 2.1 2.1 1 1 1 2 2 2 2 Solute carrier family 35 UAA PF08449.11 RLN82135.1 - 0.0016 17.7 5.5 0.0016 17.7 5.5 1.9 1 1 1 2 2 2 1 UAA transporter family TMEM234 PF10639.9 RLN82135.1 - 0.49 10.5 13.9 0.65 10.0 3.6 3.0 2 1 0 2 2 2 0 Putative transmembrane family 234 R3H PF01424.22 RLN82136.1 - 2e-05 24.4 0.5 5.1e-05 23.2 0.5 1.7 1 0 0 1 1 1 1 R3H domain zf-C3HC4_3 PF13920.6 RLN82137.1 - 1.1e-08 34.8 7.1 1.1e-08 34.8 7.1 4.4 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN82137.1 - 0.0062 16.4 6.8 0.0062 16.4 6.8 3.2 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 RLN82137.1 - 0.018 14.9 8.7 0.018 14.9 8.7 3.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Desulfoferrodox PF01880.18 RLN82137.1 - 0.06 14.0 0.4 2.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Desulfoferrodoxin FYVE PF01363.21 RLN82138.1 - 4.8e-12 45.9 12.2 4.8e-12 45.9 12.2 3.7 2 1 1 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 RLN82138.1 - 2.4e-11 43.8 3.9 2.4e-11 43.8 3.9 4.5 4 1 0 4 4 4 1 Ring finger domain zf-RING_11 PF17123.5 RLN82138.1 - 5.5e-11 42.0 1.4 5.5e-11 42.0 1.4 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 RLN82138.1 - 5.3e-08 32.7 0.3 5.3e-08 32.7 0.3 4.2 3 2 2 5 5 5 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN82138.1 - 1.2e-07 31.6 2.7 1.2e-07 31.6 2.7 4.7 4 1 1 5 5 5 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RLN82138.1 - 1.4e-07 31.3 3.3 1.4e-07 31.3 3.3 5.0 6 0 0 6 6 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN82138.1 - 3.4e-06 26.8 3.8 3.4e-06 26.8 3.8 5.0 4 1 1 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN82138.1 - 0.0072 16.6 5.9 0.0072 16.6 5.9 3.8 3 1 1 4 4 4 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 RLN82138.1 - 0.0089 16.2 2.2 0.0089 16.2 2.2 5.2 5 1 0 5 5 5 1 zinc finger of C3HC4-type, RING PHD PF00628.29 RLN82138.1 - 0.0094 15.8 4.5 0.0094 15.8 4.5 4.0 4 1 0 4 4 4 1 PHD-finger Vps39_2 PF10367.9 RLN82138.1 - 0.74 10.3 0.0 0.74 10.3 0.0 3.7 3 1 2 5 5 5 0 Vacuolar sorting protein 39 domain 2 DZR PF12773.7 RLN82138.1 - 2.8 8.1 34.5 0.15 12.1 3.9 5.0 2 2 1 3 3 3 0 Double zinc ribbon TRAF6_Z2 PF18048.1 RLN82138.1 - 3.7 7.7 7.1 1.3 9.2 3.2 2.2 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 Zn-ribbon_8 PF09723.10 RLN82138.1 - 7.7 6.7 24.3 0.53 10.4 0.6 5.5 4 1 1 5 5 5 0 Zinc ribbon domain Peptidase_M14 PF00246.24 RLN82139.1 - 1.7e-25 90.5 0.0 4.7e-25 89.0 0.0 1.8 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 RLN82139.1 - 0.0042 16.2 0.2 0.01 15.0 0.2 1.6 1 1 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Cpn60_TCP1 PF00118.24 RLN82140.1 - 1.5e-23 83.2 0.0 3e-22 78.9 0.0 2.0 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family FtsJ PF01728.19 RLN82141.1 - 3.6e-65 219.4 0.3 4.2e-65 219.2 0.3 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase ABC_membrane PF00664.23 RLN82142.1 - 6.5e-51 173.6 4.9 9.4e-51 173.1 4.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN82142.1 - 5e-35 121.0 0.1 1.2e-34 119.7 0.1 1.7 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 RLN82142.1 - 3e-07 30.1 0.1 5.4e-06 26.0 0.3 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 RLN82142.1 - 0.0058 17.1 2.3 0.21 12.0 1.9 2.9 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN82142.1 - 0.0071 16.7 0.5 0.031 14.7 0.3 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 RLN82142.1 - 0.014 15.1 0.1 0.042 13.6 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN82142.1 - 0.02 14.5 0.1 0.15 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 RLN82142.1 - 0.023 14.0 0.1 0.051 12.8 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 RLN82142.1 - 0.023 14.4 0.3 0.043 13.6 0.3 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ABC_ATPase PF09818.9 RLN82142.1 - 0.031 13.1 0.2 0.078 11.8 0.0 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class SRP54 PF00448.22 RLN82142.1 - 0.034 13.8 0.2 0.14 11.8 0.1 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DEAD PF00270.29 RLN82142.1 - 0.043 13.6 0.3 0.12 12.1 0.3 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase CbiA PF01656.23 RLN82142.1 - 0.053 13.6 0.3 0.22 11.6 0.2 2.1 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Mg_chelatase PF01078.21 RLN82142.1 - 0.053 12.9 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 RLN82142.1 - 0.062 13.0 0.1 0.11 12.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 RLN82142.1 - 0.073 12.8 1.7 0.21 11.3 1.7 1.7 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 RLN82142.1 - 0.082 12.8 0.4 0.28 11.1 0.1 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase RsgA_GTPase PF03193.16 RLN82142.1 - 0.1 12.5 0.0 0.43 10.5 0.0 2.0 2 0 0 2 2 1 0 RsgA GTPase NB-ARC PF00931.22 RLN82142.1 - 0.12 11.5 0.1 0.3 10.2 0.1 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 RLN82142.1 - 0.12 12.6 0.7 3 8.1 0.3 2.5 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 RLN82142.1 - 0.14 11.3 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.17 RLN82142.1 - 1.9 8.5 4.0 1.7 8.7 1.4 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain CCG PF02754.16 RLN82143.1 - 0.1 12.8 1.2 0.62 10.3 0.0 2.4 2 0 0 2 2 2 0 Cysteine-rich domain CENP-H PF05837.12 RLN82143.1 - 1.1 9.6 16.4 2.3 8.6 9.7 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF1664 PF07889.12 RLN82143.1 - 3 7.9 9.4 1.2 9.2 3.6 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) FapA PF03961.13 RLN82143.1 - 7.8 5.0 9.7 4.8 5.7 2.8 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A Kinesin PF00225.23 RLN82144.1 - 3.4e-91 305.7 0.0 7.7e-91 304.5 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN82144.1 - 1.9e-21 76.6 0.0 7e-21 74.7 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding SOGA PF11365.8 RLN82144.1 - 0.24 12.5 17.4 0.79 10.9 1.6 3.7 3 0 0 3 3 3 0 Protein SOGA zf-C4pol PF14260.6 RLN82144.1 - 0.3 11.6 3.9 0.34 11.4 0.8 2.7 2 1 1 3 3 3 0 C4-type zinc-finger of DNA polymerase delta DUF4407 PF14362.6 RLN82144.1 - 2.7 7.3 31.5 1.3 8.3 19.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 RLN82144.1 - 7.3 4.0 30.1 10 3.4 30.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMCO5 PF14992.6 RLN82144.1 - 8.1 5.9 20.2 37 3.7 19.5 2.2 1 1 1 2 2 2 0 TMCO5 family PPR_2 PF13041.6 RLN82145.1 - 2.3e-41 139.8 1.2 4.4e-13 49.2 0.1 6.7 3 1 4 7 7 7 6 PPR repeat family PPR PF01535.20 RLN82145.1 - 4.3e-30 101.8 1.7 7.4e-06 25.9 0.1 7.7 7 0 0 7 7 7 5 PPR repeat PPR_3 PF13812.6 RLN82145.1 - 1.8e-26 92.0 0.0 1.2e-09 38.1 0.0 4.4 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 RLN82145.1 - 3.8e-23 80.9 0.1 9.8e-08 31.6 0.0 6.2 7 0 0 7 7 7 3 PPR repeat PPR_long PF17177.4 RLN82145.1 - 1.8e-18 66.7 0.0 4.2e-12 45.9 0.0 3.3 2 1 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 RLN82145.1 - 0.00034 19.6 0.0 0.00052 19.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 Clathrin PF00637.20 RLN82145.1 - 0.00048 20.0 0.0 0.0066 16.3 0.0 2.7 1 1 2 3 3 3 1 Region in Clathrin and VPS TPR_19 PF14559.6 RLN82145.1 - 0.001 19.5 1.0 0.0044 17.5 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat MNE1 PF13762.6 RLN82145.1 - 0.0077 16.2 0.0 2.7 8.0 0.0 3.0 2 1 0 2 2 2 1 Mitochondrial splicing apparatus component TPR_4 PF07721.14 RLN82145.1 - 0.056 14.1 4.9 4.8 8.1 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN82145.1 - 0.8 10.7 8.8 32 5.7 0.0 5.4 5 1 1 6 6 5 0 Tetratricopeptide repeat DDE_1 PF03184.19 RLN82146.1 - 3e-33 114.9 0.1 4.6e-33 114.3 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN82146.1 - 2.3e-09 37.2 0.1 1.2e-08 34.8 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 RLN82146.1 - 0.018 14.8 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_ABP1_N PF18107.1 RLN82146.1 - 0.026 14.2 0.1 0.21 11.3 0.0 2.3 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain Pkinase PF00069.25 RLN82147.1 - 1.5e-46 159.0 0.0 6.3e-40 137.2 0.0 4.0 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 RLN82147.1 - 3.7e-43 147.7 0.0 4.8e-37 127.6 0.0 4.1 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 RLN82147.1 - 8e-05 22.7 0.2 0.00032 20.7 0.2 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 RLN82147.1 - 0.0022 17.6 0.0 0.006 16.2 0.0 1.7 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 RLN82147.1 - 0.038 12.8 0.0 0.11 11.3 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 RLN82147.1 - 0.11 11.9 0.6 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_pol3_alpha PF07733.12 RLN82147.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha NTPase domain Pkinase_Tyr PF07714.17 RLN82148.1 - 4.6e-45 153.9 0.0 9.8e-40 136.5 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN82148.1 - 2.3e-41 141.9 0.0 9.3e-36 123.5 0.0 3.4 4 0 0 4 4 4 2 Protein kinase domain Pkinase_fungal PF17667.1 RLN82148.1 - 0.0075 15.1 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 RLN82148.1 - 0.075 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Cystatin PF00031.21 RLN82148.1 - 0.15 12.3 0.0 0.67 10.3 0.0 2.0 2 0 0 2 2 2 0 Cystatin domain MLTR_LBD PF17765.1 RLN82148.1 - 2 8.5 10.5 0.05 13.7 0.8 3.0 3 1 1 4 4 4 0 MmyB-like transcription regulator ligand binding domain RCC1 PF00415.18 RLN82186.1 - 1.3e-74 246.6 14.0 1e-14 54.8 0.1 7.8 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 RLN82186.1 - 3.7e-55 187.6 0.0 8e-55 186.5 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DEAD PF00270.29 RLN82186.1 - 1.3e-45 155.3 0.0 2.7e-45 154.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RCC1_2 PF13540.6 RLN82186.1 - 2.8e-32 109.8 39.6 2.8e-08 33.3 0.4 8.8 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Helicase_C PF00271.31 RLN82186.1 - 1.9e-27 95.8 0.0 7.2e-27 93.9 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SPRY PF00622.28 RLN82186.1 - 3.7e-20 72.2 0.1 1.2e-19 70.6 0.1 2.0 1 0 0 1 1 1 1 SPRY domain Laminin_G_3 PF13385.6 RLN82186.1 - 1.2e-08 35.2 0.0 2.7e-07 30.9 0.0 3.0 3 1 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily UBA PF00627.31 RLN82186.1 - 0.00019 21.3 0.0 0.00048 20.0 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain DUF29 PF01724.16 RLN82186.1 - 0.046 13.9 0.9 0.15 12.3 0.9 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF29 SWI2_SNF2 PF18766.1 RLN82186.1 - 0.057 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase ORC_WH_C PF18137.1 RLN82186.1 - 3.4 7.8 6.6 11 6.1 2.1 3.1 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal PPP4R2 PF09184.11 RLN82186.1 - 4 6.9 15.2 12 5.4 15.2 1.7 1 0 0 1 1 1 0 PPP4R2 Pox_Ag35 PF03286.14 RLN82186.1 - 6.3 6.5 12.6 12 5.7 8.1 2.9 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Trypsin_2 PF13365.6 RLN82187.1 - 4.3e-15 56.9 1.0 1.4e-14 55.2 0.2 2.1 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 RLN82187.1 - 0.00011 22.1 3.9 0.00011 22.1 3.9 2.3 2 1 0 2 2 2 1 Trypsin Peptidase_S46 PF10459.9 RLN82187.1 - 0.055 12.1 0.7 3.3 6.2 0.2 2.1 2 0 0 2 2 2 0 Peptidase S46 p450 PF00067.22 RLN82188.1 - 4e-09 35.7 0.0 4.7e-09 35.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 RLN82189.1 - 0.00021 20.2 0.0 0.00025 19.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FYVE PF01363.21 RLN82190.1 - 7.8e-14 51.6 13.9 1.9e-13 50.3 13.9 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN82190.1 - 0.0016 18.6 8.3 0.0031 17.7 8.3 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger INTAP PF16617.5 RLN82190.1 - 0.15 12.4 8.6 0.39 11.1 8.6 1.6 1 0 0 1 1 1 0 Intersectin and clathrin adaptor AP2 binding region Complex1_LYR PF05347.15 RLN82191.1 - 7.8e-07 29.1 0.0 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) EF-G-binding_N PF07299.11 RLN82191.1 - 0.043 14.3 0.6 0.2 12.2 0.1 1.9 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal Complex1_LYR_2 PF13233.6 RLN82191.1 - 0.063 14.0 0.1 0.099 13.4 0.1 1.4 1 1 0 1 1 1 0 Complex1_LYR-like Corazonin PF17308.2 RLN82191.1 - 0.13 12.7 0.0 0.39 11.1 0.1 1.7 1 1 1 2 2 2 0 Pro-corazonin UCH PF00443.29 RLN82219.1 - 6.8e-39 133.9 0.0 9e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN82219.1 - 3.5e-10 40.0 0.0 2.5e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase EGF_2 PF07974.13 RLN82220.1 - 3.1e-10 40.3 62.4 0.00028 21.2 4.1 5.3 5 0 0 5 5 5 5 EGF-like domain Laminin_EGF PF00053.24 RLN82220.1 - 0.021 15.0 44.8 4.5 7.5 10.2 4.4 3 1 1 4 4 4 0 Laminin EGF domain EGF PF00008.27 RLN82220.1 - 2.8 8.3 45.7 5 7.5 1.3 5.1 5 0 0 5 5 5 0 EGF-like domain Tic110 PF16940.5 RLN82220.1 - 7.9 4.8 5.4 15 4.0 4.8 1.7 2 0 0 2 2 2 0 Chloroplast envelope transporter zf-CCHC_3 PF13917.6 RLN82221.1 - 0.00071 19.5 0.0 0.0029 17.5 0.0 2.1 1 0 0 1 1 1 1 Zinc knuckle PI3_PI4_kinase PF00454.27 RLN82222.1 - 4.3e-27 95.5 0.0 2.3e-20 73.5 0.0 2.3 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase Nop16 PF09420.10 RLN82222.1 - 0.92 9.5 5.5 2.3 8.2 5.5 1.6 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 BSP_II PF05432.11 RLN82222.1 - 4.4 6.9 31.0 0.19 11.4 19.0 3.2 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) DPPIV_N PF00930.21 RLN82223.1 - 3.7e-71 239.8 0.0 2e-69 234.1 0.0 2.8 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.12 RLN82223.1 - 3.3e-06 26.9 1.0 0.081 12.9 0.0 3.8 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Peptidase_S9 PF00326.21 RLN82223.1 - 0.00077 19.0 0.1 0.0019 17.7 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Proteasome_A_N PF10584.9 RLN82223.1 - 0.1 12.3 0.4 12 5.7 0.0 2.5 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature PP2C PF00481.21 RLN82224.1 - 1.5e-64 218.2 0.0 2.1e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RLN82224.1 - 6.8e-06 25.9 0.0 1.6e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 RLN82224.1 - 0.00042 20.3 0.1 0.31 10.9 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) GDP_Man_Dehyd PF16363.5 RLN82225.1 - 9e-48 163.4 0.0 1.4e-47 162.7 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RLN82225.1 - 2.9e-43 148.1 0.0 3.9e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 RLN82225.1 - 5.7e-08 32.2 0.1 0.0004 19.6 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 RLN82225.1 - 3.9e-07 29.4 0.0 6e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 RLN82225.1 - 1.5e-05 24.3 0.0 2.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RLN82225.1 - 2.5e-05 23.6 0.1 0.18 10.9 0.0 2.4 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.25 RLN82225.1 - 0.0031 17.0 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase DUF1815 PF08844.10 RLN82225.1 - 0.058 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) UDPG_MGDP_dh_N PF03721.14 RLN82225.1 - 0.084 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain KR PF08659.10 RLN82225.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 KR domain CAP_N PF01213.19 RLN82226.1 - 0.018 14.5 9.0 0.018 14.5 9.0 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 RLN82226.1 - 0.13 12.3 7.9 0.23 11.5 7.9 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 VIR_N PF15912.5 RLN82226.1 - 0.93 9.0 9.7 0.38 10.3 7.2 1.6 1 1 1 2 2 2 0 Virilizer, N-terminal Mito_fiss_reg PF05308.11 RLN82226.1 - 7.2 6.6 15.8 9.7 6.2 14.7 1.8 1 1 0 1 1 1 0 Mitochondrial fission regulator DUF3292 PF11696.8 RLN82226.1 - 8.2 4.7 9.2 12 4.2 9.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3292) ArgJ PF01960.18 RLN82227.1 - 9.4e-06 24.6 0.0 1.1e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 ArgJ family HSF_DNA-bind PF00447.17 RLN82229.1 - 2.5e-25 88.9 0.8 2.5e-25 88.9 0.8 1.6 2 0 0 2 2 2 1 HSF-type DNA-binding RapA_C PF12137.8 RLN82229.1 - 0.00093 18.3 4.7 0.0014 17.8 4.7 1.2 1 0 0 1 1 1 1 RNA polymerase recycling family C-terminal APG6_N PF17675.1 RLN82229.1 - 0.086 13.4 4.4 0.13 12.8 4.4 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region YabA PF06156.13 RLN82229.1 - 0.52 11.0 4.2 0.48 11.1 2.8 1.6 1 1 0 1 1 1 0 Initiation control protein YabA PspB PF06667.12 RLN82229.1 - 1.5 8.9 5.7 9 6.4 4.5 2.6 2 1 0 2 2 2 0 Phage shock protein B Ank_2 PF12796.7 RLN82230.1 - 1.3e-35 121.8 0.8 8.2e-10 39.1 0.3 6.3 1 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN82230.1 - 1.3e-30 102.0 14.2 0.0015 18.8 0.0 9.6 9 1 1 10 10 10 6 Ankyrin repeat Ank PF00023.30 RLN82230.1 - 8.9e-29 98.7 19.5 1.3e-06 28.6 0.0 8.5 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 RLN82230.1 - 5.5e-27 93.8 8.2 2.9e-10 40.5 0.1 8.1 6 3 3 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN82230.1 - 1e-22 79.9 19.4 3.1e-10 40.1 0.2 7.5 8 0 0 8 8 8 5 Ankyrin repeats (many copies) TIR_2 PF13676.6 RLN82230.1 - 2.5e-16 60.3 0.0 2.2e-08 34.7 0.0 2.6 2 0 0 2 2 2 2 TIR domain TIR PF01582.20 RLN82230.1 - 0.00079 19.3 0.2 0.91 9.3 0.1 2.4 2 0 0 2 2 2 2 TIR domain Pkinase PF00069.25 RLN82232.1 - 7.4e-51 173.0 0.0 1e-50 172.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN82232.1 - 2.9e-44 151.3 0.0 3.9e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1180 PF06679.12 RLN82232.1 - 0.017 15.5 0.1 0.017 15.5 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) EphA2_TM PF14575.6 RLN82232.1 - 0.054 14.4 0.0 0.13 13.1 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Haspin_kinase PF12330.8 RLN82232.1 - 0.11 11.5 0.1 0.19 10.7 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 RLN82232.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN82232.1 - 0.18 10.6 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF1736 PF08409.11 RLN82233.1 - 4.7e-17 61.7 0.8 1.1e-16 60.6 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_1 PF00515.28 RLN82233.1 - 1.8e-07 30.7 7.6 0.0016 18.2 0.1 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN82233.1 - 3.8e-06 26.7 6.4 0.016 15.4 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN82233.1 - 7.4e-06 25.7 12.3 0.012 15.7 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN82233.1 - 7.5e-06 26.2 11.0 0.047 14.0 0.3 5.4 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN82233.1 - 9.6e-06 25.6 4.7 0.53 10.8 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN82233.1 - 1.2e-05 24.9 3.8 0.16 11.7 0.0 4.8 5 0 0 5 5 5 2 TPR repeat TPR_16 PF13432.6 RLN82233.1 - 7.8e-05 23.2 14.5 0.056 14.1 0.4 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN82233.1 - 0.0013 19.1 3.6 0.78 10.3 0.3 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN82233.1 - 0.0024 18.0 2.4 2.5 8.3 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN82233.1 - 0.0026 18.3 5.0 0.12 13.0 0.1 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN82233.1 - 0.0031 18.2 11.3 3.8 8.6 0.0 6.3 4 3 2 6 6 6 1 Tetratricopeptide repeat DUF2723 PF11028.8 RLN82233.1 - 0.0038 17.2 1.1 0.0086 16.0 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2723) NARP1 PF12569.8 RLN82233.1 - 0.031 13.2 0.0 0.27 10.1 0.1 2.0 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 PPR PF01535.20 RLN82233.1 - 0.046 14.0 0.0 0.14 12.4 0.0 1.9 1 0 0 1 1 1 0 PPR repeat TPR_7 PF13176.6 RLN82233.1 - 0.34 11.0 8.4 0.36 11.0 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN82234.1 - 5e-05 23.9 3.0 5e-05 23.9 3.0 4.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN82234.1 - 5.9e-05 23.5 18.3 0.0052 17.3 1.6 5.1 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN82234.1 - 0.0025 17.7 2.1 9.3 6.5 0.2 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN82234.1 - 0.0053 17.0 10.2 2.1 8.6 0.2 4.8 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 RLN82234.1 - 0.0083 16.3 1.4 1.6 9.1 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN82234.1 - 0.016 15.0 1.0 4.6 7.2 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat RHH_4 PF13467.6 RLN82234.1 - 0.081 12.8 0.6 24 4.9 0.0 3.9 5 0 0 5 5 5 0 Ribbon-helix-helix domain TPR_20 PF14561.6 RLN82234.1 - 0.11 12.8 14.0 0.31 11.4 0.5 4.5 4 2 1 5 5 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 RLN82234.1 - 0.13 12.7 0.0 0.44 11.0 0.0 1.9 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation TPR_15 PF13429.6 RLN82234.1 - 0.14 11.3 9.6 1.8 7.7 3.9 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 RLN82234.1 - 0.14 12.6 0.0 0.14 12.6 0.0 3.5 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN82234.1 - 0.19 11.9 0.1 0.19 11.9 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN82234.1 - 0.28 12.1 13.7 0.53 11.2 0.4 5.4 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 RLN82234.1 - 0.31 10.7 7.3 35 4.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat-like domain TPR_12 PF13424.6 RLN82234.1 - 2.5 8.4 10.2 3.9 7.8 1.8 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN82234.1 - 5.2 7.9 8.4 94 4.0 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 RLN82235.1 - 8.7e-41 140.0 0.0 1e-40 139.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN82235.1 - 1.4e-36 126.1 0.0 1.8e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN82235.1 - 0.093 12.1 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RLN82235.1 - 0.094 11.6 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 RLN82235.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Yop-YscD_cpl PF16697.5 RLN82270.1 - 3.1e-05 24.2 0.0 9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 RLN82270.1 - 5e-05 23.6 0.0 9.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 FHA domain RsfS PF02410.15 RLN82271.1 - 3.5e-15 56.2 0.2 1.9e-14 53.9 0.1 2.0 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation Asp PF00026.23 RLN82273.1 - 6.9e-62 209.7 0.0 1e-61 209.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RLN82273.1 - 5.5e-13 49.5 0.1 1e-05 25.9 0.0 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 RLN82273.1 - 0.00056 19.7 0.1 0.0014 18.5 0.1 1.7 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal zf-H2C2_2 PF13465.6 RLN82274.1 - 3e-07 30.6 17.2 0.00017 21.8 4.1 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 RLN82274.1 - 1.7e-05 25.0 21.5 0.0039 17.6 2.2 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN82274.1 - 0.015 16.0 15.4 1 10.4 1.5 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 RLN82274.1 - 0.41 11.3 4.4 0.43 11.2 0.5 2.6 1 1 1 2 2 2 0 FOXP coiled-coil domain GST_N_2 PF13409.6 RLN82275.1 - 1.1e-14 54.4 0.0 2.5e-14 53.3 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 RLN82275.1 - 0.00025 21.4 0.0 0.027 14.9 0.0 2.2 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN82276.1 - 4.7e-06 26.8 0.0 7.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 RLN82276.1 - 0.066 13.6 0.0 0.099 13.1 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain UcrQ PF02939.16 RLN82277.1 - 9.5e-10 38.3 0.0 1.1e-09 38.1 0.0 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 RLN82277.1 - 4.8e-06 26.9 0.0 6.2e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 TPR_1 PF00515.28 RLN82278.1 - 5.5e-13 48.1 12.5 7.8e-05 22.3 0.7 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 RLN82278.1 - 1.9e-11 44.1 8.7 3e-06 27.4 0.2 4.1 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN82278.1 - 1.4e-08 34.2 10.1 0.0014 18.6 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN82278.1 - 2.3e-08 33.6 3.7 0.038 13.9 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN82278.1 - 4.5e-05 23.3 9.9 0.01 16.0 0.5 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN82278.1 - 0.00034 21.2 1.8 3.8 8.6 0.0 5.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 RLN82278.1 - 0.00038 20.8 1.1 3.2 8.6 0.3 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 RLN82278.1 - 0.0014 18.0 4.2 0.011 15.1 3.0 2.9 2 1 0 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 RLN82278.1 - 0.0022 17.9 2.1 0.38 10.9 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.20 RLN82278.1 - 0.03 14.5 0.3 7.4 7.1 0.1 2.8 2 0 0 2 2 2 0 PPR repeat IQ PF00612.27 RLN82278.1 - 0.36 10.7 10.7 11 6.1 0.2 4.4 4 0 0 4 4 4 0 IQ calmodulin-binding motif ANAPC3 PF12895.7 RLN82278.1 - 0.42 10.9 3.4 12 6.2 0.6 3.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 RLN82278.1 - 0.53 10.0 4.4 13 5.6 0.1 3.4 3 0 0 3 3 3 0 TPR repeat Ank_4 PF13637.6 RLN82279.1 - 4.6e-40 135.5 12.0 4.6e-05 23.9 0.0 11.1 9 2 4 13 13 13 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN82279.1 - 5.1e-36 123.1 1.7 8.4e-09 35.9 0.1 7.5 4 1 5 9 9 9 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN82279.1 - 1.7e-31 107.8 18.0 0.0013 19.0 0.1 15.3 6 2 9 15 15 15 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN82279.1 - 5.8e-19 66.2 0.8 12 6.9 0.1 13.7 13 1 1 14 14 14 1 Ankyrin repeat DUF5049 PF16468.5 RLN82279.1 - 7.5e-09 35.3 0.0 0.31 10.9 0.0 8.2 4 2 6 10 10 10 1 Domain of unknown function (DUF5049) Ank PF00023.30 RLN82279.1 - 0.012 16.0 0.9 1.4e+02 3.1 0.1 6.5 4 3 2 6 6 6 0 Ankyrin repeat CNOT1_HEAT PF16418.5 RLN82279.1 - 0.031 14.4 0.3 46 4.0 0.0 4.6 4 1 1 5 5 5 0 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF3322 PF11795.8 RLN82279.1 - 0.035 14.1 3.2 33 4.4 0.1 5.4 3 2 4 7 7 7 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) ThiF PF00899.21 RLN82281.1 - 3e-15 56.3 0.0 4e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family VPS13 PF16908.5 RLN82323.1 - 3.8e-26 92.3 0.0 8.1e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 RLN82323.1 - 9.7e-14 51.5 0.1 2.3e-13 50.3 0.1 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 PDZ_6 PF17820.1 RLN82323.1 - 0.027 14.3 0.0 8.4 6.3 0.0 2.6 2 0 0 2 2 2 0 PDZ domain IQ PF00612.27 RLN82323.1 - 0.37 10.7 1.7 1.4 8.9 1.7 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif MORN PF02493.20 RLN82326.1 - 6.7e-11 41.4 13.1 3e-07 29.9 2.8 3.8 3 0 0 3 3 3 2 MORN repeat MaoC_dehydrat_N PF13452.6 RLN82326.1 - 0.035 14.3 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase Latarcin PF10279.9 RLN82327.1 - 0.035 14.5 0.3 0.38 11.2 0.0 2.6 2 2 0 2 2 2 0 Latarcin precursor baeRF_family12 PF18856.1 RLN82327.1 - 0.061 13.9 0.1 0.17 12.5 0.1 1.9 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 PROCN PF08083.11 RLN82328.1 - 2.3e-204 678.7 6.9 3.6e-204 678.0 6.9 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 RLN82328.1 - 1.1e-127 424.3 0.2 2.1e-127 423.5 0.2 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 RLN82328.1 - 1e-89 298.6 2.0 2.6e-89 297.2 2.0 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 U5_2-snRNA_bdg PF10597.9 RLN82328.1 - 1e-72 242.5 0.0 2e-72 241.6 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 RLN82328.1 - 9.2e-47 157.3 0.4 2.5e-46 155.9 0.4 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Flu_PB1 PF00602.17 RLN82369.1 - 0.1 10.7 1.1 0.15 10.1 1.1 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 Helicase_C_2 PF13307.6 RLN82371.1 - 4e-53 180.1 0.0 9.6e-53 178.9 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 RLN82371.1 - 1.7e-42 145.1 0.8 3.6e-42 143.9 0.1 1.9 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.15 RLN82371.1 - 4.8e-05 23.4 0.1 0.0074 16.3 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RLN82371.1 - 0.00025 20.8 0.2 0.0046 16.8 0.2 2.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 RLN82371.1 - 0.0046 16.4 0.2 2.3 7.6 0.1 2.5 2 0 0 2 2 2 2 PhoH-like protein Zot PF05707.12 RLN82371.1 - 0.021 14.5 0.2 0.43 10.2 0.1 2.8 3 0 0 3 3 3 0 Zonular occludens toxin (Zot) HBB PF06777.11 RLN82371.1 - 0.061 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Helical and beta-bridge domain T2SSE PF00437.20 RLN82371.1 - 0.14 11.2 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Amidase PF01425.21 RLN82372.1 - 3.8e-89 299.7 0.1 1.1e-88 298.2 0.1 1.6 1 1 0 1 1 1 1 Amidase ACBP PF00887.19 RLN82373.1 - 9e-17 61.1 0.0 1.8e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein SF-assemblin PF06705.11 RLN82373.1 - 0.013 14.9 2.5 0.02 14.3 2.5 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin CREPT PF16566.5 RLN82373.1 - 0.048 13.8 3.3 0.1 12.8 3.3 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF3963 PF13124.6 RLN82373.1 - 0.14 12.1 1.8 0.31 11.1 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) Hexokinase_2 PF03727.16 RLN82373.1 - 0.36 10.2 1.5 0.75 9.2 1.5 1.5 1 0 0 1 1 1 0 Hexokinase TMF_TATA_bd PF12325.8 RLN82373.1 - 1.2 9.4 9.8 2.8 8.2 2.0 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TolA_bind_tri PF16331.5 RLN82373.1 - 3.2 7.9 13.0 3.4 7.8 10.0 2.3 1 1 1 2 2 2 0 TolA binding protein trimerisation YabA PF06156.13 RLN82373.1 - 8.2 7.1 6.5 60 4.4 5.4 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Toxin_29 PF08116.11 RLN82374.1 - 0.0049 16.8 1.0 1.5 8.9 0.2 3.8 3 0 0 3 3 3 1 PhTx neurotoxin family DUF983 PF06170.12 RLN82374.1 - 0.054 13.9 1.7 20 5.7 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF983) BSMAP PF12280.8 RLN82374.1 - 0.81 9.9 4.0 11 6.2 0.1 2.3 2 0 0 2 2 2 0 Brain specific membrane anchored protein zf-dskA_traR PF01258.17 RLN82374.1 - 1.6 8.8 17.4 2.4 8.2 0.0 4.8 5 0 0 5 5 5 0 Prokaryotic dksA/traR C4-type zinc finger 5-FTHF_cyc-lig PF01812.20 RLN82375.1 - 9.3e-31 107.1 0.0 1e-30 107.0 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family FeS_assembly_P PF01883.19 RLN82375.1 - 0.11 12.7 0.3 2 8.6 0.3 2.3 2 0 0 2 2 2 0 Iron-sulfur cluster assembly protein DnaJ PF00226.31 RLN82376.1 - 1.9e-11 43.9 0.3 4.4e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 DnaJ domain 5-FTHF_cyc-lig PF01812.20 RLN82376.1 - 0.0013 18.6 0.2 0.0021 17.9 0.2 1.3 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family RTBV_P46 PF06216.11 RLN82378.1 - 0.043 12.7 0.2 0.077 11.9 0.2 1.3 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein UPF0121 PF03661.13 RLN82381.1 - 5.6e-54 183.1 10.9 8.2e-54 182.5 10.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) TPR_2 PF07719.17 RLN82381.1 - 3.6e-09 36.0 9.4 0.036 14.2 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN82381.1 - 9.7e-06 25.2 4.7 1.4 8.9 0.5 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 RLN82381.1 - 9.5e-05 22.9 11.4 0.52 11.3 0.2 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.17 RLN82381.1 - 0.0004 20.8 4.9 0.049 14.1 0.7 2.4 1 1 1 2 2 2 2 Bacterial transcriptional activator domain TPR_11 PF13414.6 RLN82381.1 - 0.0044 16.7 2.7 1.4 8.6 0.1 3.1 2 1 1 3 3 3 2 TPR repeat TPR_12 PF13424.6 RLN82381.1 - 0.02 15.2 6.3 0.04 14.2 1.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 RLN82381.1 - 0.023 14.9 4.3 0.56 10.6 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN82381.1 - 0.025 15.2 4.4 0.025 15.2 4.4 2.8 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN82381.1 - 0.054 13.4 0.4 6.1 6.8 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 RLN82381.1 - 0.083 12.4 0.8 5.1 6.6 0.2 2.4 2 0 0 2 2 2 0 SHNi-TPR DUF2594 PF10769.9 RLN82381.1 - 0.18 11.8 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2594) TPR_19 PF14559.6 RLN82381.1 - 0.55 10.8 6.3 2.2 8.8 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 RLN82420.1 - 8.5e-45 153.2 0.0 1.3e-44 152.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN82420.1 - 1.2e-38 132.9 0.0 1.8e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN82420.1 - 1.4e-06 27.9 1.2 1.9e-06 27.4 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN82420.1 - 0.00023 20.1 0.1 0.00023 20.1 0.1 2.2 3 1 0 3 3 3 1 Fungal protein kinase APH PF01636.23 RLN82420.1 - 0.0044 17.0 4.5 0.026 14.4 0.1 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RLN82420.1 - 0.016 14.5 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like CPSase_L_D2 PF02786.17 RLN82421.1 - 2.6e-21 76.1 0.1 4.2e-21 75.4 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain MGS PF02142.22 RLN82421.1 - 4.8e-16 58.7 0.0 1.1e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 MGS-like domain ATP-grasp PF02222.22 RLN82421.1 - 1.5e-08 34.4 0.0 2.3e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 RLN82421.1 - 6.4e-06 25.9 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 RLN82421.1 - 7.8e-06 25.6 0.3 1.6e-05 24.5 0.3 1.4 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus GAGA_bind PF06217.12 RLN82422.1 - 0.0083 16.4 11.7 0.012 15.9 11.7 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family PHM7_cyt PF14703.6 RLN82422.1 - 0.022 15.0 15.4 0.041 14.1 15.4 1.4 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Neur_chan_memb PF02932.16 RLN82422.1 - 0.063 13.3 3.7 0.071 13.2 3.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Vfa1 PF08432.10 RLN82422.1 - 0.063 13.6 24.9 0.097 13.0 24.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Exonuc_VII_L PF02601.15 RLN82422.1 - 0.065 12.8 7.0 0.075 12.6 7.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4661 PF15576.6 RLN82422.1 - 0.21 11.5 8.4 0.32 10.9 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) DUF2052 PF09747.9 RLN82422.1 - 0.54 10.3 14.8 0.76 9.9 14.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Borrelia_P83 PF05262.11 RLN82422.1 - 0.74 8.2 28.0 0.86 8.0 28.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF5094 PF17015.5 RLN82422.1 - 1.2 9.2 16.1 1.7 8.8 16.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) AAA_23 PF13476.6 RLN82422.1 - 1.2 9.6 15.3 1.8 9.1 15.3 1.3 1 0 0 1 1 1 0 AAA domain DUF3807 PF12720.7 RLN82422.1 - 2.1 8.6 18.0 3.3 8.0 18.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Membralin PF09746.9 RLN82422.1 - 5.1 6.0 5.9 5.9 5.8 5.9 1.1 1 0 0 1 1 1 0 Tumour-associated protein Zip PF02535.22 RLN82422.1 - 7.7 5.6 8.1 9.5 5.3 8.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 RLN82422.1 - 8.5 6.1 22.1 12 5.6 22.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ank_2 PF12796.7 RLN82423.1 - 2.3e-51 172.3 2.4 6.7e-17 61.9 0.1 4.1 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN82423.1 - 1.6e-47 159.3 9.6 3.7e-11 43.3 0.4 5.8 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 RLN82423.1 - 1.6e-44 148.4 2.0 3.6e-07 30.3 0.0 7.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 RLN82423.1 - 2.3e-37 126.6 13.0 1e-10 41.7 0.2 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN82423.1 - 2.6e-34 113.3 0.9 0.00023 21.4 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat PhyH PF05721.13 RLN82425.1 - 0.0017 18.7 0.0 0.18 12.0 0.0 2.2 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) U79_P34 PF03064.16 RLN82425.1 - 0.15 11.4 0.4 1.6 8.1 0.2 2.0 2 0 0 2 2 2 0 HSV U79 / HCMV P34 FLYWCH PF04500.16 RLN82426.1 - 1.1e-07 31.8 0.5 1.1e-07 31.8 0.5 1.8 2 0 0 2 2 2 1 FLYWCH zinc finger domain MULE PF10551.9 RLN82426.1 - 0.0011 19.4 0.1 0.0021 18.4 0.1 1.4 1 0 0 1 1 1 1 MULE transposase domain DUF4413 PF14372.6 RLN82427.1 - 0.053 13.9 0.0 0.096 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) CALM_bind PF16025.5 RLN82427.1 - 0.38 11.3 7.4 0.91 10.0 2.4 2.2 1 1 1 2 2 2 0 Calcium-dependent calmodulin binding DUF4618 PF15397.6 RLN82428.1 - 1.3 8.4 10.9 0.35 10.3 4.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Pkinase PF00069.25 RLN82429.1 - 2.4e-22 79.5 0.0 4.7e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN82429.1 - 4.3e-12 45.9 0.0 8.4e-11 41.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase SRP-alpha_N PF04086.13 RLN82429.1 - 6.8 6.5 9.2 11 5.9 9.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ribosomal_L13 PF00572.18 RLN82430.1 - 8.8e-06 26.0 0.1 2.8e-05 24.4 0.0 1.8 2 1 1 3 3 3 1 Ribosomal protein L13 Pkinase PF00069.25 RLN82461.1 - 1.1e-48 166.0 0.0 1.4e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN82461.1 - 5e-44 150.5 0.0 6.6e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Podoplanin PF05808.11 RLN82461.1 - 0.0016 18.5 0.6 0.0031 17.6 0.6 1.4 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.6 RLN82461.1 - 0.011 15.7 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Haspin_kinase PF12330.8 RLN82461.1 - 0.091 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain EphA2_TM PF14575.6 RLN82461.1 - 0.1 13.5 0.1 0.23 12.3 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain APH PF01636.23 RLN82461.1 - 0.11 12.4 0.1 0.38 10.6 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Protocadherin PF08374.11 RLN82461.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Protocadherin Amnionless PF14828.6 RLN82461.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Amnionless TraL PF07178.11 RLN82461.1 - 0.16 12.4 0.0 0.37 11.3 0.0 1.5 1 0 0 1 1 1 0 TraL protein Pkinase_fungal PF17667.1 RLN82461.1 - 0.17 10.6 0.0 0.32 9.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase SKG6 PF08693.10 RLN82461.1 - 7.3 6.1 9.4 19 4.8 9.4 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Elicitin PF00964.17 RLN82462.1 - 3.9e-05 23.7 1.8 7.5e-05 22.7 1.7 1.6 1 1 0 1 1 1 1 Elicitin Pkinase PF00069.25 RLN82463.1 - 1.3e-48 165.7 0.0 1.8e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN82463.1 - 1.1e-43 149.4 0.0 1.4e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN82463.1 - 0.014 14.2 0.1 0.022 13.5 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase PepSY_TM_like_2 PF16357.5 RLN82463.1 - 0.035 14.1 0.1 0.066 13.2 0.1 1.3 1 0 0 1 1 1 0 Putative PepSY_TM-like Haspin_kinase PF12330.8 RLN82463.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF2627 PF11118.8 RLN82463.1 - 0.13 12.8 0.1 0.52 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) VSP PF03302.13 RLN82463.1 - 0.8 8.5 1.5 1.2 7.9 1.5 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein F-box-like PF12937.7 RLN82464.1 - 0.12 12.3 0.7 0.2 11.6 0.7 1.4 1 0 0 1 1 1 0 F-box-like Ank_2 PF12796.7 RLN82465.1 - 9.8e-32 109.4 10.1 1.7e-07 31.7 0.1 5.2 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN82465.1 - 2.4e-21 75.8 13.7 0.00018 22.0 0.0 7.8 4 2 4 9 9 9 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN82465.1 - 4.3e-20 71.5 8.9 0.00024 21.3 0.1 8.9 2 1 8 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN82465.1 - 8.5e-15 53.4 3.2 2 9.3 0.0 10.4 13 0 0 13 13 13 4 Ankyrin repeat DUF5049 PF16468.5 RLN82465.1 - 2.7e-07 30.4 0.0 3.4 7.6 0.0 6.3 3 2 4 7 7 7 2 Domain of unknown function (DUF5049) Ank PF00023.30 RLN82465.1 - 3.8e-06 27.1 1.7 2.6 8.7 0.0 6.5 5 2 0 5 5 5 1 Ankyrin repeat DUF1979 PF09322.10 RLN82465.1 - 0.001 18.9 0.2 0.61 10.0 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1979) DUF3322 PF11795.8 RLN82465.1 - 0.0038 17.3 1.0 2.1 8.3 0.0 4.4 2 1 1 4 4 4 1 Uncharacterized protein conserved in bacteria N-term (DUF3322) fn3 PF00041.21 RLN82506.1 - 0.027 14.8 2.0 0.13 12.6 0.1 2.7 2 1 0 2 2 2 0 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RLN82506.1 - 0.04 14.5 0.8 1.2 9.7 0.0 2.5 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Anemone_cytotox PF06369.12 RLN82506.1 - 0.19 11.4 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Sea anemone cytotoxic protein UPF0242 PF06785.11 RLN82506.1 - 9.6 6.3 46.0 2.1 8.4 8.0 2.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus EST1_DNA_bind PF10373.9 RLN82507.1 - 2e-45 155.5 0.0 1.2e-44 152.9 0.0 2.2 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 RLN82507.1 - 2.3e-15 57.4 0.1 9.1e-15 55.5 0.0 2.1 2 0 0 2 2 2 1 Telomerase activating protein Est1 UPF0240 PF06784.11 RLN82507.1 - 0.0002 21.5 0.0 0.0004 20.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) RRN3 PF05327.11 RLN82508.1 - 1e-94 318.1 0.4 1e-94 318.1 0.4 3.3 2 1 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Drc1-Sld2 PF11719.8 RLN82508.1 - 0.018 14.6 0.1 0.032 13.8 0.1 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Glycoprot_B_PH2 PF17417.2 RLN82508.1 - 0.15 12.5 0.0 0.43 10.9 0.0 1.7 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B PH-like domain Ran_BP1 PF00638.18 RLN82512.1 - 7.6e-37 126.3 1.0 1.2e-36 125.7 1.0 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 RLN82512.1 - 0.00017 21.5 0.8 0.00055 19.9 0.8 1.8 1 1 0 1 1 1 1 WH1 domain DUF5486 PF17588.2 RLN82512.1 - 0.035 14.0 0.3 0.077 12.9 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5486) AAA_11 PF13086.6 RLN82513.1 - 8.1e-61 206.1 0.3 8.1e-61 206.1 0.3 3.4 3 2 0 3 3 3 1 AAA domain AAA_12 PF13087.6 RLN82513.1 - 4.3e-10 39.6 0.1 7.8e-10 38.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RLN82513.1 - 4.1e-08 33.2 3.8 2.5e-06 27.3 3.8 2.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RLN82513.1 - 1e-05 25.9 3.4 1.3e-05 25.6 0.5 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN82513.1 - 0.051 13.9 0.1 0.22 11.9 0.1 2.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 RLN82513.1 - 0.074 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 RLN82513.1 - 0.19 11.4 0.7 14 5.4 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Homeobox_KN PF05920.11 RLN82514.1 - 3.4e-17 62.0 0.2 3.4e-17 62.0 0.2 2.1 3 0 0 3 3 3 1 Homeobox KN domain Homeodomain PF00046.29 RLN82514.1 - 8.2e-10 38.4 0.6 1.9e-09 37.2 0.6 1.6 1 0 0 1 1 1 1 Homeodomain SLC35F PF06027.12 RLN82515.1 - 1.2e-50 172.7 11.7 1.2e-41 143.1 2.9 2.0 1 1 1 2 2 2 2 Solute carrier family 35 CRT-like PF08627.10 RLN82515.1 - 6.7e-10 38.4 0.8 6.7e-10 38.4 0.8 1.5 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 RLN82515.1 - 1.3e-09 37.8 7.6 3.1e-09 36.5 3.1 2.1 1 1 1 2 2 2 2 UAA transporter family EamA PF00892.20 RLN82515.1 - 1.2e-08 35.3 10.3 0.00021 21.5 3.5 2.9 2 1 1 3 3 3 2 EamA-like transporter family Mg_trans_NIPA PF05653.14 RLN82515.1 - 7.5e-06 25.3 5.2 0.0012 18.0 3.0 2.3 2 1 0 2 2 2 2 Magnesium transporter NIPA DAGAT PF03982.13 RLN82516.1 - 1.9e-39 135.4 0.5 9.2e-37 126.5 0.5 2.9 1 1 0 1 1 1 1 Diacylglycerol acyltransferase Cullin_Nedd8 PF10557.9 RLN82517.1 - 2.1e-19 69.3 1.6 2.8e-19 68.9 1.6 1.2 1 0 0 1 1 1 1 Cullin protein neddylation domain Wza_C PF18412.1 RLN82517.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Outer-membrane lipoprotein Wza C-terminal domain DEAD PF00270.29 RLN82518.1 - 4.7e-10 39.5 0.1 0.00017 21.4 0.0 3.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN82518.1 - 1.3e-07 31.9 0.1 3.3e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN82518.1 - 0.0018 18.3 0.0 0.13 12.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 RLN82518.1 - 0.089 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain XhlA PF10779.9 RLN82518.1 - 0.63 10.3 4.5 1.2 9.4 4.5 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Sporozoite_P67 PF05642.11 RLN82519.1 - 0.62 8.1 7.4 0.77 7.8 7.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Zn_clus PF00172.18 RLN82519.1 - 4 7.7 10.8 11 6.3 10.8 1.8 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_membrane PF00664.23 RLN82552.1 - 9.2e-20 71.4 8.7 8e-16 58.5 1.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN82552.1 - 2.3e-16 60.6 0.0 5.1e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Nexin_C PF08628.12 RLN82552.1 - 0.0021 18.6 0.0 0.0045 17.5 0.0 1.5 1 0 0 1 1 1 1 Sorting nexin C terminal RsgA_GTPase PF03193.16 RLN82552.1 - 0.0044 16.9 0.3 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 RLN82552.1 - 0.0063 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 RLN82552.1 - 0.026 14.2 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RLN82552.1 - 0.028 14.8 0.0 0.092 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 RLN82552.1 - 0.034 13.2 0.0 0.076 12.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_membrane_3 PF13748.6 RLN82552.1 - 0.056 12.7 5.5 0.34 10.1 0.2 2.3 2 0 0 2 2 2 0 ABC transporter transmembrane region NACHT PF05729.12 RLN82552.1 - 0.14 12.1 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 RLN82552.1 - 0.15 12.6 0.5 0.39 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 RLN82552.1 - 0.15 12.1 0.0 0.43 10.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase SepZ PF06066.11 RLN82553.1 - 0.04 14.1 0.2 0.066 13.4 0.2 1.3 1 0 0 1 1 1 0 SepZ TMEM70 PF06979.12 RLN82554.1 - 1.1e-19 71.2 0.5 4.7e-12 46.5 0.1 2.0 2 0 0 2 2 2 2 Assembly, mitochondrial proton-transport ATP synth complex FOP_dimer PF09398.10 RLN82555.1 - 0.0035 17.5 0.0 0.0077 16.5 0.0 1.5 1 0 0 1 1 1 1 FOP N terminal dimerisation domain DUF4208 PF13907.6 RLN82556.1 - 4.4e-06 27.0 0.0 0.019 15.4 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4208) CHDCT2 PF08074.11 RLN82556.1 - 0.0029 17.8 0.1 0.011 15.9 0.1 2.0 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain Hid1 PF12722.7 RLN82556.1 - 0.5 8.4 16.8 0.021 13.0 6.9 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 RLN82556.1 - 0.83 9.7 10.0 0.32 11.0 4.1 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 RLN82556.1 - 7 4.8 19.6 3.2 5.9 9.1 2.4 2 0 0 2 2 2 0 CDC45-like protein PGP_phosphatase PF09419.10 RLN82557.1 - 2.7e-43 147.5 0.0 3.2e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 RLN82557.1 - 0.00053 20.0 0.0 0.00093 19.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like TetR_C_31 PF17940.1 RLN82557.1 - 0.057 13.6 0.2 11 6.3 0.0 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Hemerythrin PF01814.23 RLN82558.1 - 0.0082 16.8 0.1 3.4 8.3 0.0 2.3 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain SNF2_N PF00176.23 RLN82559.1 - 4.2e-60 203.3 1.6 8.1e-60 202.4 1.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain PHD PF00628.29 RLN82559.1 - 5e-27 93.5 65.6 7.5e-10 38.6 6.2 6.8 6 0 0 6 6 6 5 PHD-finger Helicase_C PF00271.31 RLN82559.1 - 4.5e-18 65.6 0.0 1e-17 64.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 RLN82559.1 - 1.8e-16 60.0 0.0 3.7e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Bromodomain zf-HC5HC2H PF13771.6 RLN82559.1 - 4.6e-15 55.7 51.9 3.2e-12 46.5 3.0 6.9 5 1 1 6 6 6 4 PHD-like zinc-binding domain Chromo PF00385.24 RLN82559.1 - 1.2e-10 41.1 0.1 8.6e-06 25.6 0.0 3.7 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain zf-HC5HC2H_2 PF13832.6 RLN82559.1 - 1.3e-10 41.4 47.2 9.2e-09 35.5 2.3 6.6 3 2 3 6 6 6 4 PHD-zinc-finger like domain ResIII PF04851.15 RLN82559.1 - 9.2e-09 35.5 0.0 2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 RLN82559.1 - 1.3e-05 24.5 0.0 3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD_2 PF13831.6 RLN82559.1 - 0.0001 21.7 35.4 0.0013 18.3 0.5 5.4 5 0 0 5 5 4 3 PHD-finger DEAD PF00270.29 RLN82559.1 - 0.00015 21.6 0.0 0.00035 20.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase PDZ PF00595.24 RLN82559.1 - 0.01 16.2 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 RLN82559.1 - 0.015 15.2 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 PDZ domain SWI2_SNF2 PF18766.1 RLN82559.1 - 0.017 14.8 0.0 0.041 13.6 0.0 1.6 1 1 0 1 1 1 0 SWI2/SNF2 ATPase ABC_membrane PF00664.23 RLN82560.1 - 2e-43 149.1 8.7 2.6e-43 148.7 8.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN82560.1 - 1.1e-34 119.9 0.0 2.5e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN82560.1 - 2.6e-06 27.0 0.0 4.9e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 RLN82560.1 - 0.0011 17.8 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 RLN82560.1 - 0.0086 16.3 0.1 0.044 14.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 RLN82560.1 - 0.039 14.2 0.8 0.78 10.0 0.8 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 RLN82560.1 - 0.046 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 RLN82560.1 - 0.087 13.3 0.5 2.1 8.8 0.2 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 RLN82560.1 - 0.21 11.1 0.0 0.42 10.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Transp_Tc5_C PF04236.15 RLN82561.1 - 0.12 12.7 3.7 2.7 8.4 0.8 2.3 1 1 1 2 2 2 0 Tc5 transposase C-terminal domain DEAD PF00270.29 RLN82586.1 - 3.8e-06 26.8 0.4 0.014 15.2 0.1 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase CBS PF00571.28 RLN82586.1 - 0.058 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 CBS domain Helicase_C PF00271.31 RLN82586.1 - 0.14 12.5 0.0 0.44 10.9 0.0 1.9 1 1 0 1 1 1 0 Helicase conserved C-terminal domain p450 PF00067.22 RLN82587.1 - 2.1e-65 221.3 0.0 3.6e-65 220.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Clathrin_lg_ch PF01086.17 RLN82588.1 - 1.5e-10 41.6 13.5 2.2e-09 37.7 13.5 2.1 1 1 0 1 1 1 1 Clathrin light chain TPD PF14811.6 RLN82589.1 - 0.16 11.8 0.1 0.41 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function TPD sequence-motif THUMP PF02926.17 RLN82590.1 - 1.9e-14 54.0 0.8 4.5e-14 52.8 0.8 1.6 1 0 0 1 1 1 1 THUMP domain TarH PF02203.15 RLN82590.1 - 0.069 13.1 5.3 0.86 9.5 3.7 2.3 2 0 0 2 2 2 0 Tar ligand binding domain homologue Ribosomal_L29e PF01779.17 RLN82591.1 - 1.4e-19 70.1 11.0 1.4e-19 70.1 11.0 2.2 2 1 0 2 2 2 1 Ribosomal L29e protein family Med19 PF10278.9 RLN82591.1 - 6.2 6.7 16.1 7.7 6.4 16.1 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Adaptin_binding PF10199.9 RLN82592.1 - 5.2e-18 65.8 7.8 1.3e-17 64.5 7.8 1.7 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Ras PF00071.22 RLN82592.1 - 0.00072 19.2 0.2 0.0018 17.9 0.2 1.6 1 0 0 1 1 1 1 Ras family NPR1_interact PF15699.5 RLN82592.1 - 0.021 15.4 7.3 0.25 12.0 0.4 2.7 2 0 0 2 2 2 0 NPR1 interacting Transglut_core PF01841.19 RLN82592.1 - 0.038 14.4 0.4 0.11 13.0 0.0 1.9 2 0 0 2 2 2 0 Transglutaminase-like superfamily Cwf_Cwc_15 PF04889.12 RLN82592.1 - 1.5 8.5 10.0 2.4 7.9 10.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Parathyroid PF01279.17 RLN82592.1 - 3.4 8.3 6.4 2 9.0 0.7 2.9 3 1 1 4 4 4 0 Parathyroid hormone family Prefoldin PF02996.17 RLN82593.1 - 2.8e-05 24.0 0.1 4.3e-05 23.4 0.1 1.3 1 1 0 1 1 1 1 Prefoldin subunit AdoHcyase PF05221.17 RLN82594.1 - 3.9e-142 472.8 0.0 4.4e-142 472.6 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 RLN82594.1 - 7.1e-82 273.3 4.6 1.1e-81 272.7 4.6 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 RLN82594.1 - 1.9e-09 37.1 0.6 3.2e-09 36.4 0.6 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 RLN82594.1 - 1.6e-05 24.6 0.6 3e-05 23.6 0.6 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ELFV_dehydrog PF00208.21 RLN82594.1 - 0.00063 19.5 0.3 0.0013 18.5 0.3 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.20 RLN82594.1 - 0.001 19.1 0.6 0.003 17.6 0.6 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 RLN82594.1 - 0.0018 18.6 0.9 0.038 14.3 0.8 2.8 2 1 0 2 2 2 1 TrkA-N domain THF_DHG_CYH_C PF02882.19 RLN82594.1 - 0.0018 17.6 3.1 0.0077 15.6 3.2 1.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 RLN82594.1 - 0.021 15.3 0.4 0.067 13.6 0.4 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding DUP PF00674.18 RLN82594.1 - 0.025 14.7 0.0 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 DUP family WD40 PF00400.32 RLN82595.1 - 6.9e-16 58.3 6.3 6.2e-05 23.7 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN82595.1 - 7.2e-08 32.6 0.5 0.016 15.5 0.0 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 RLN82595.1 - 2.1e-07 31.2 0.6 0.031 14.8 0.0 4.4 4 0 0 4 4 4 2 PQQ-like domain PQQ PF01011.21 RLN82595.1 - 5e-06 26.2 0.4 0.21 11.5 0.1 3.3 3 0 0 3 3 3 2 PQQ enzyme repeat Nup160 PF11715.8 RLN82595.1 - 0.00025 19.9 1.1 1.4 7.4 0.1 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Hira PF07569.11 RLN82595.1 - 0.025 14.3 1.8 0.34 10.6 0.0 3.2 2 2 3 5 5 5 0 TUP1-like enhancer of split Nucleoporin_N PF08801.11 RLN82595.1 - 0.13 11.0 0.0 0.3 9.8 0.0 1.6 2 0 0 2 2 2 0 Nup133 N terminal like Sdh5 PF03937.16 RLN82596.1 - 3.2e-22 78.3 0.1 4.8e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase DUF2624 PF11116.8 RLN82596.1 - 0.061 14.2 0.2 0.79 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) Galactosyl_T PF01762.21 RLN82596.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Galactosyltransferase vATP-synt_E PF01991.18 RLN82597.1 - 2.1e-43 148.1 12.6 2.5e-43 147.8 12.6 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit PAXNEB PF05625.11 RLN82597.1 - 0.034 13.3 0.4 0.045 12.9 0.4 1.1 1 0 0 1 1 1 0 PAXNEB protein Sds3 PF08598.11 RLN82598.1 - 7.3e-07 29.4 2.1 7.3e-07 29.4 2.1 1.6 2 0 0 2 2 2 1 Sds3-like Pep_M12B_propep PF01562.19 RLN82598.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Reprolysin family propeptide ERp29 PF07749.12 RLN82598.1 - 3.4 8.6 5.3 4.2 8.3 0.3 2.7 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain X8 PF07983.13 RLN82600.1 - 1.1e-10 42.0 0.7 3.2e-10 40.6 0.3 2.1 2 0 0 2 2 2 1 X8 domain Cellulase PF00150.18 RLN82600.1 - 4.2e-09 36.2 1.5 8.7e-09 35.2 1.5 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.24 RLN82600.1 - 0.023 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel tRNA-synt_2b PF00587.25 RLN82601.1 - 2.7e-27 95.9 0.0 4.7e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 RLN82601.1 - 1.6e-11 44.4 4.7 2.7e-11 43.7 4.7 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Cellulase PF00150.18 RLN82602.1 - 6.4e-10 38.9 1.5 1.8e-09 37.4 1.5 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) X8 PF07983.13 RLN82602.1 - 7.2e-10 39.4 0.2 2e-09 38.0 0.2 1.8 1 0 0 1 1 1 1 X8 domain AP_endonuc_2 PF01261.24 RLN82602.1 - 0.007 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyco_hydro_42 PF02449.15 RLN82602.1 - 0.11 11.8 0.7 0.44 9.8 0.6 1.8 1 1 0 1 1 1 0 Beta-galactosidase Cellulase PF00150.18 RLN82603.1 - 1.3e-11 44.4 1.1 2.4e-11 43.6 1.1 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) X8 PF07983.13 RLN82603.1 - 3.8e-09 37.1 0.0 1.5e-08 35.2 0.0 2.1 1 0 0 1 1 1 1 X8 domain AP_endonuc_2 PF01261.24 RLN82603.1 - 0.00096 18.6 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Imm_superinfect PF14373.6 RLN82603.1 - 0.024 14.5 0.1 0.053 13.4 0.1 1.6 1 0 0 1 1 1 0 Superinfection immunity protein Glyco_hydro_42 PF02449.15 RLN82603.1 - 0.14 11.5 4.6 0.34 10.2 3.1 2.4 2 1 0 2 2 2 0 Beta-galactosidase ACPS PF01648.20 RLN82604.1 - 6.9e-16 58.4 0.1 2.4e-15 56.7 0.0 1.9 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily LCD1 PF09798.9 RLN82605.1 - 1.6e-11 43.5 0.8 0.0015 17.2 0.0 3.3 1 1 1 2 2 2 1 DNA damage checkpoint protein FKBP_C PF00254.28 RLN82605.1 - 0.00013 22.2 0.0 0.00048 20.4 0.0 2.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase YhcG_C PF06250.11 RLN82605.1 - 0.054 13.3 0.3 0.32 10.8 0.0 2.2 2 0 0 2 2 2 0 YhcG PDDEXK nuclease domain NPV_P10 PF05531.12 RLN82605.1 - 5.3 7.6 16.7 1.5e+02 2.9 0.4 4.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Macoilin PF09726.9 RLN82605.1 - 9.7 4.6 59.8 0.076 11.6 39.4 2.5 1 1 1 2 2 2 0 Macoilin family MIP PF00230.20 RLN82645.1 - 3.1e-55 187.4 8.9 3.7e-55 187.1 8.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 RLN82646.1 - 6.4e-54 183.0 4.7 8.9e-54 182.6 4.7 1.2 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 RLN82647.1 - 8e-44 150.0 6.1 9.8e-44 149.7 6.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein Polysacc_synt_C PF14667.6 RLN82647.1 - 0.85 9.7 12.9 3.9 7.5 1.8 3.3 1 1 2 3 3 3 0 Polysaccharide biosynthesis C-terminal domain MIP PF00230.20 RLN82648.1 - 4.5e-11 42.9 4.0 5.1e-11 42.7 4.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Metallophos_C PF14008.6 RLN82649.1 - 3.7e-16 59.7 0.1 1.1e-15 58.3 0.1 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 RLN82649.1 - 1.9e-08 35.1 0.5 3.1e-08 34.4 0.4 1.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 RLN82650.1 - 1.1e-18 67.6 11.6 2.2e-18 66.6 11.6 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 RLN82650.1 - 6.8e-06 26.7 0.1 1.2e-05 25.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FTZ PF03867.14 RLN82650.1 - 0.056 13.0 7.0 0.082 12.4 7.0 1.3 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region DUF2369 PF10179.9 RLN82650.1 - 0.19 12.1 3.1 0.15 12.4 1.4 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) PolyA_pol PF01743.20 RLN82651.1 - 3e-26 92.3 0.3 6e-26 91.3 0.3 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 RLN82651.1 - 5.5e-10 38.9 0.0 1.3e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A LPD5 PF18799.1 RLN82651.1 - 0.19 12.1 0.1 0.56 10.6 0.0 1.7 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 5 Peptidase_S8 PF00082.22 RLN82652.1 - 2.7e-44 151.6 6.9 5e-44 150.8 6.9 1.5 1 0 0 1 1 1 1 Subtilase family DUF2269 PF10027.9 RLN82652.1 - 0.062 13.4 0.3 0.14 12.2 0.3 1.5 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) Herpes_UL73 PF03554.13 RLN82652.1 - 2.5 8.2 6.4 11 6.0 0.7 3.8 3 0 0 3 3 3 0 UL73 viral envelope glycoprotein TIR_2 PF13676.6 RLN82653.1 - 1.5e-09 38.5 0.0 1.3e-08 35.4 0.0 2.3 2 0 0 2 2 2 1 TIR domain BTK PF00779.19 RLN82653.1 - 3.8e-05 23.4 0.9 0.00013 21.7 0.9 1.9 1 0 0 1 1 1 1 BTK motif Motilin_assoc PF04643.12 RLN82656.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide MULE PF10551.9 RLN82659.1 - 0.0028 18.0 0.0 0.0073 16.7 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Peptidase_C48 PF02902.19 RLN82659.1 - 0.028 14.3 0.1 0.054 13.3 0.1 1.4 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain YdfA_immunity PF12127.8 RLN82699.1 - 6.6 5.7 6.3 2.3 7.2 2.7 1.7 2 0 0 2 2 2 0 SigmaW regulon antibacterial Pkinase PF00069.25 RLN82701.1 - 8.7e-76 254.8 0.0 1.2e-75 254.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN82701.1 - 9.2e-40 136.6 0.0 1.3e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 RLN82701.1 - 5.5e-09 36.5 0.0 7.5e-08 32.8 0.0 2.2 1 1 0 1 1 1 1 PH domain Kdo PF06293.14 RLN82701.1 - 6.6e-07 28.9 0.0 2.1e-05 24.0 0.0 2.7 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN82701.1 - 5.1e-05 22.7 0.0 0.00036 19.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RLN82701.1 - 0.00024 20.0 0.0 0.0004 19.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN82701.1 - 0.002 18.1 0.0 0.01 15.8 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 RLN82701.1 - 0.088 12.3 0.0 0.39 10.2 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL 2-ph_phosp PF04029.14 RLN82701.1 - 0.1 11.8 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase ARL2_Bind_BART PF11527.8 RLN82702.1 - 4.7e-08 33.2 0.4 5.7e-08 32.9 0.4 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART zf-CCHC_2 PF13696.6 RLN82703.1 - 3.1e-27 94.0 27.9 8.3e-11 41.5 2.2 3.4 3 0 0 3 3 3 3 Zinc knuckle WD40 PF00400.32 RLN82703.1 - 7.1e-16 58.3 9.1 0.00033 21.4 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat zf-CCHC PF00098.23 RLN82703.1 - 1.4e-12 47.0 20.3 0.00028 20.8 4.0 3.5 3 0 0 3 3 3 3 Zinc knuckle ANAPC4_WD40 PF12894.7 RLN82703.1 - 3e-06 27.4 1.0 0.0042 17.4 0.2 2.6 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain zf-CCHC_3 PF13917.6 RLN82703.1 - 8.9e-05 22.4 19.4 0.031 14.3 1.1 3.3 2 1 1 3 3 3 3 Zinc knuckle zf-CCHC_5 PF14787.6 RLN82703.1 - 0.00044 19.9 15.3 0.046 13.4 0.5 3.4 3 0 0 3 3 3 2 GAG-polyprotein viral zinc-finger eIF2A PF08662.11 RLN82703.1 - 0.038 13.9 0.7 0.064 13.1 0.7 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A HypA PF01155.19 RLN82703.1 - 7.7 6.6 6.3 24 5.0 0.3 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Bromodomain PF00439.25 RLN82704.1 - 4.6e-14 52.3 0.0 1.2e-13 50.9 0.0 1.7 2 0 0 2 2 2 1 Bromodomain G_glu_transpept PF01019.21 RLN82757.1 - 2e-139 465.6 0.1 2.3e-139 465.5 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Snf7 PF03357.21 RLN82758.1 - 0.066 12.8 1.6 0.08 12.5 1.6 1.1 1 0 0 1 1 1 0 Snf7 FYVE PF01363.21 RLN82760.1 - 9.4e-06 25.7 11.6 2e-05 24.6 11.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN82760.1 - 0.00057 20.1 12.6 0.0089 16.2 12.8 2.2 1 1 1 2 2 2 1 FYVE-type zinc finger Siva PF05458.12 RLN82760.1 - 0.36 10.5 10.5 1.9 8.2 10.6 2.0 2 1 0 2 2 2 0 Cd27 binding protein (Siva) C1_2 PF03107.16 RLN82760.1 - 1.7 9.0 7.0 1 9.7 4.0 2.1 2 0 0 2 2 2 0 C1 domain IBR PF01485.21 RLN82760.1 - 6.4 7.1 12.9 21 5.4 9.8 2.9 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Na_H_antiporter PF03553.14 RLN82761.1 - 1.7e-37 129.3 2.0 1.7e-37 129.3 2.0 2.6 1 1 1 2 2 2 2 Na+/H+ antiporter family COX2_TM PF02790.15 RLN82761.1 - 0.0087 16.2 0.5 0.23 11.7 0.0 3.4 3 0 0 3 3 3 1 Cytochrome C oxidase subunit II, transmembrane domain PqqD PF05402.12 RLN82795.1 - 0.15 12.3 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) DNA_ligase_OB_2 PF14743.6 RLN82796.1 - 1.3e-27 95.6 0.2 8.3e-27 93.0 0.0 2.2 2 0 0 2 2 2 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 RLN82796.1 - 1.5e-12 47.6 0.0 8.5e-12 45.1 0.0 2.1 1 1 0 1 1 1 1 ATP dependent DNA ligase domain PTCB-BRCT PF12738.7 RLN82796.1 - 2e-06 27.7 0.1 5.4e-06 26.3 0.1 1.8 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 RLN82796.1 - 0.00012 22.4 0.0 0.00029 21.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RNA_ligase PF09414.10 RLN82796.1 - 0.0032 17.8 0.1 0.018 15.4 0.1 2.0 1 1 0 1 1 1 1 RNA ligase ABC2_membrane PF01061.24 RLN82797.1 - 7.4e-32 110.5 18.8 1.1e-31 109.9 18.8 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN82797.1 - 3.9e-24 85.7 0.0 6.4e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 RLN82797.1 - 1.5e-06 27.6 13.5 1.5e-06 27.6 13.5 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 RLN82797.1 - 3e-06 27.3 0.1 0.022 14.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN82797.1 - 0.00039 20.4 0.2 0.00085 19.3 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN82797.1 - 0.0013 18.5 0.0 0.0028 17.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN82797.1 - 0.0021 18.4 0.0 0.0035 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 RLN82797.1 - 0.0047 17.5 0.0 0.0082 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RLN82797.1 - 0.083 13.2 0.0 0.28 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.6 RLN82797.1 - 0.088 11.6 0.0 0.18 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain SMC_N PF02463.19 RLN82797.1 - 0.12 11.8 0.1 0.64 9.4 0.1 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Pkinase PF00069.25 RLN82798.1 - 1.1e-43 149.6 0.0 1.2e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN82798.1 - 1.1e-30 106.8 0.0 1.5e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN82798.1 - 0.00083 18.2 0.0 0.0011 17.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN82798.1 - 0.0011 18.3 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN82798.1 - 0.0041 17.1 0.1 1.3 8.9 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 RLN82798.1 - 0.047 13.0 0.2 0.1 11.9 0.1 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Actin PF00022.19 RLN82799.1 - 7.5e-69 232.3 0.0 2.8e-63 213.9 0.0 2.7 2 1 0 2 2 2 2 Actin Pkinase PF00069.25 RLN82800.1 - 2.9e-56 190.7 0.0 2.4e-55 187.8 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN82800.1 - 1.4e-20 73.7 0.0 5e-20 71.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN82800.1 - 0.00033 20.1 0.1 0.00073 18.9 0.1 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN82800.1 - 0.0077 15.6 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN82800.1 - 0.0078 16.2 0.3 0.017 15.1 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 RLN82800.1 - 0.073 12.7 0.1 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 MIP PF00230.20 RLN82801.1 - 0.00025 20.8 0.1 0.00031 20.5 0.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 RLN82802.1 - 1.9e-55 188.1 7.8 2.3e-55 187.8 7.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein Phage_holin_8 PF16931.5 RLN82802.1 - 0.098 12.6 0.0 0.098 12.6 0.0 2.0 3 0 0 3 3 3 0 Putative phage holin CPP1-like PF11833.8 RLN82802.1 - 0.35 10.5 0.9 0.9 9.2 0.0 1.9 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF4064 PF13273.6 RLN82802.1 - 1.5 9.1 5.8 0.48 10.7 0.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Polysacc_synt_C PF14667.6 RLN82802.1 - 1.7 8.7 12.4 2.5 8.1 0.1 3.2 2 1 1 3 3 3 0 Polysaccharide biosynthesis C-terminal domain CPSase_L_D2 PF02786.17 RLN82803.1 - 1e-75 253.9 0.1 1.6e-75 253.3 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 RLN82803.1 - 1.2e-43 148.2 0.1 2.3e-43 147.2 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 RLN82803.1 - 5.6e-36 122.9 0.0 1.4e-35 121.6 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 RLN82803.1 - 7.6e-17 60.9 1.0 2.7e-16 59.2 1.0 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme PCC_BT PF18140.1 RLN82803.1 - 6.3e-09 36.3 0.1 2.3e-07 31.2 0.0 2.4 2 0 0 2 2 2 1 Propionyl-coenzyme A carboxylase BT domain ATP-grasp PF02222.22 RLN82803.1 - 3.3e-07 30.0 0.0 9.2e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 RLN82803.1 - 4.2e-06 26.4 0.0 1.3e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_ST PF14397.6 RLN82803.1 - 0.0012 18.2 0.0 0.021 14.1 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATP-grasp_5 PF13549.6 RLN82803.1 - 0.0021 17.6 0.0 0.0043 16.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 RLN82803.1 - 0.0061 16.4 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 RLN82803.1 - 0.02 14.9 0.1 0.1 12.6 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain DUF2118 PF09891.9 RLN82803.1 - 0.028 14.4 0.1 0.074 13.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) RnfC_N PF13375.6 RLN82803.1 - 0.061 13.3 0.3 0.18 11.8 0.3 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain VIT1 PF01988.19 RLN82804.1 - 5.6e-55 186.5 1.6 7.3e-55 186.2 1.6 1.2 1 0 0 1 1 1 1 VIT family GatB_Yqey PF02637.18 RLN82804.1 - 0.064 13.1 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 GatB domain DUF4349 PF14257.6 RLN82804.1 - 0.071 12.6 0.1 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) MerE PF05052.12 RLN82804.1 - 0.15 12.0 1.1 0.33 10.9 1.1 1.6 1 0 0 1 1 1 0 MerE protein ANAPC4_WD40 PF12894.7 RLN82805.1 - 1.3e-05 25.4 0.2 3.8 7.9 0.0 5.0 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain cNMP_binding PF00027.29 RLN82806.1 - 6.7e-21 74.2 1.3 6.2e-10 39.0 0.0 3.0 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 RLN82806.1 - 0.17 11.6 0.2 7.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Cupin domain IPP-2 PF04979.14 RLN82807.1 - 1e-20 74.8 5.8 1e-20 74.8 5.8 1.9 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) SHIPPO-rpt PF07004.12 RLN82808.1 - 5.2e-19 68.2 19.2 0.0016 19.2 0.4 6.1 6 0 0 6 6 6 5 Sperm-tail PG-rich repeat Ank_2 PF12796.7 RLN82851.1 - 1.3e-81 269.3 12.6 4e-18 65.8 0.2 6.3 1 1 6 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN82851.1 - 1.7e-49 165.5 7.2 1.4e-09 38.3 0.0 7.7 3 2 6 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN82851.1 - 6.7e-49 158.2 0.2 0.0006 20.1 0.0 10.5 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.6 RLN82851.1 - 3.7e-47 157.8 10.5 2.5e-09 37.2 0.0 8.9 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 RLN82851.1 - 3e-44 147.6 7.6 0.00055 20.3 0.0 10.3 8 2 1 9 9 9 8 Ankyrin repeat Pkinase PF00069.25 RLN82851.1 - 1.3e-41 142.8 0.0 1.9e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN82851.1 - 7.4e-41 140.1 0.0 1.1e-40 139.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN82851.1 - 0.0047 16.3 0.0 0.0086 15.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN82851.1 - 0.025 13.9 0.0 0.51 9.6 0.0 2.5 2 1 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN82851.1 - 0.055 13.4 0.1 1.5 8.7 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4145 PF13643.6 RLN82852.1 - 0.026 14.7 0.2 0.63 10.2 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4145) zf-CCCH_2 PF14608.6 RLN82852.1 - 0.052 14.1 0.8 0.052 14.1 0.8 3.2 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger PPI_Ypi1 PF07491.11 RLN82854.1 - 3.1e-16 58.9 0.9 3.1e-16 58.9 0.9 2.2 2 1 0 2 2 2 1 Protein phosphatase inhibitor VEFS-Box PF09733.9 RLN82855.1 - 2.9e-21 75.7 0.6 5.4e-21 74.8 0.6 1.3 1 0 0 1 1 1 1 VEFS-Box of polycomb protein Lipase_3 PF01764.25 RLN82856.1 - 1.9e-09 37.5 0.0 4.1e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 RLN82856.1 - 0.00034 21.3 0.3 0.0022 18.6 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN82856.1 - 0.00096 18.9 0.1 0.0091 15.7 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2974 PF11187.8 RLN82856.1 - 0.0076 15.8 0.0 0.5 9.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 RLN82856.1 - 0.008 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2048 PF09752.9 RLN82856.1 - 0.012 14.8 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Mem_trans PF03547.18 RLN82856.1 - 0.013 13.9 0.0 0.013 13.9 0.0 1.5 2 0 0 2 2 1 0 Membrane transport protein UPF0227 PF05728.12 RLN82856.1 - 0.049 13.6 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 RLN82856.1 - 0.2 11.4 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family SR-25 PF10500.9 RLN82856.1 - 0.25 10.9 12.7 0.41 10.2 12.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HKR_ArcB_TM PF18415.1 RLN82856.1 - 0.52 11.1 7.9 1.8 9.5 7.9 1.9 1 0 0 1 1 1 0 Histidine kinase receptor ArcB trans-membrane domain IMUP PF15761.5 RLN82856.1 - 0.76 10.5 12.7 1.6 9.5 12.7 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF755 PF05501.11 RLN82856.1 - 2.6 8.3 16.8 5.1 7.4 16.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) TsaE PF02367.17 RLN82857.1 - 2e-25 89.2 0.0 2.4e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE FSIP1 PF15554.6 RLN82858.1 - 4.2 6.4 13.3 0.59 9.2 7.9 2.3 2 1 0 2 2 2 0 FSIP1 family Abhydro_lipase PF04083.16 RLN82899.1 - 4.4e-19 67.8 0.0 7.4e-19 67.1 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 RLN82899.1 - 3.8e-14 53.0 0.0 5.4e-14 52.5 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold RNA_pol_Rpb5_N PF03871.14 RLN82899.1 - 0.0031 18.1 0.0 0.014 15.9 0.1 2.1 3 0 0 3 3 3 1 RNA polymerase Rpb5, N-terminal domain Hydrolase_4 PF12146.8 RLN82899.1 - 0.0084 15.4 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 C166 PF17615.2 RLN82899.1 - 0.052 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function Abhydro_lipase PF04083.16 RLN82900.1 - 1.2e-17 63.2 0.0 2.3e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 RLN82900.1 - 3.5e-12 46.5 0.1 5.3e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN82900.1 - 0.00079 18.8 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Mis12 PF05859.12 RLN82901.1 - 5.1e-10 39.5 3.1 5.1e-10 39.5 3.1 2.0 2 1 0 2 2 2 1 Mis12 protein DUF4817 PF16087.5 RLN82901.1 - 0.059 13.2 0.3 2 8.3 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) E2F_CC-MB PF16421.5 RLN82901.1 - 0.13 12.6 8.0 3.1 8.2 0.2 2.9 3 0 0 3 3 3 0 E2F transcription factor CC-MB domain RNA12 PF10443.9 RLN82901.1 - 0.19 10.4 6.8 0.24 10.1 6.4 1.3 1 1 0 1 1 1 0 RNA12 protein DUF1283 PF06932.11 RLN82901.1 - 0.59 10.4 4.1 11 6.3 0.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1283) BLOC1_2 PF10046.9 RLN82901.1 - 2.1 8.7 11.6 0.19 12.1 1.6 2.8 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YabA PF06156.13 RLN82901.1 - 2.3 8.9 14.2 1.5 9.5 7.7 3.2 1 1 1 2 2 2 0 Initiation control protein YabA DASH_Dam1 PF08653.10 RLN82901.1 - 2.5 8.0 5.9 14 5.5 0.0 3.9 4 0 0 4 4 4 0 DASH complex subunit Dam1 AMP-binding PF00501.28 RLN82902.1 - 2.6e-92 309.6 0.0 3.5e-92 309.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN82902.1 - 6.3e-05 23.9 0.1 0.00018 22.4 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Tyr_Deacylase PF02580.16 RLN82903.1 - 6.1e-23 81.9 0.0 1.2e-22 81.0 0.0 1.4 1 1 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase CTP_transf_like PF01467.26 RLN82904.1 - 1.9e-12 47.6 0.0 2.8e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like Methyltransf_16 PF10294.9 RLN82905.1 - 4.4e-10 39.6 0.0 9.8e-10 38.4 0.0 1.5 1 1 0 1 1 1 1 Lysine methyltransferase DUF3182 PF11379.8 RLN82905.1 - 0.043 12.8 0.4 0.072 12.0 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3182) Glyco_hydro_63 PF03200.16 RLN82906.1 - 1.5e-08 33.8 1.5 2.1e-07 30.1 0.8 2.4 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Trehalase PF01204.18 RLN82906.1 - 0.00011 21.2 6.5 0.00016 20.7 6.5 1.2 1 0 0 1 1 1 1 Trehalase Jacalin PF01419.17 RLN82906.1 - 0.0019 18.1 0.4 0.0034 17.3 0.4 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Beta-prism_lec PF16458.5 RLN82906.1 - 0.034 14.1 1.1 0.057 13.4 0.1 1.9 2 0 0 2 2 2 0 Beta-prism lectin Abhydro_lipase PF04083.16 RLN82908.1 - 1.3e-20 72.7 0.1 2.3e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 RLN82908.1 - 1.5e-10 41.1 1.0 1.9e-10 40.8 1.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 RLN82909.1 - 2.2e-19 68.8 0.0 5.1e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 RLN82909.1 - 1.2e-14 54.5 0.0 3.2e-14 53.2 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN82909.1 - 0.0012 18.1 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 RNA_pol_Rpb5_N PF03871.14 RLN82909.1 - 0.071 13.7 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain DUF3577 PF12101.8 RLN82909.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3577) Abhydro_lipase PF04083.16 RLN82910.1 - 1.1e-19 69.7 0.0 2.4e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 RLN82910.1 - 4.9e-12 46.0 0.2 7.5e-12 45.4 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN82910.1 - 0.0048 16.2 0.0 0.0066 15.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 RNA_pol_Rpb5_N PF03871.14 RLN82910.1 - 0.071 13.7 0.0 0.51 10.9 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb5, N-terminal domain FYVE PF01363.21 RLN82911.1 - 8.5e-14 51.5 7.6 1.6e-13 50.6 7.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger TPR_2 PF07719.17 RLN82911.1 - 6.8e-11 41.4 3.1 0.02 15.0 0.0 4.2 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN82911.1 - 1.8e-09 37.0 0.1 0.002 18.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN82911.1 - 2e-09 36.8 1.7 0.0004 20.2 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN82911.1 - 3.5e-09 36.3 0.7 0.078 12.9 0.0 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN82911.1 - 9.9e-09 34.7 0.1 0.014 15.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN82911.1 - 2.1e-07 30.5 0.0 0.0098 15.6 0.0 2.5 2 0 0 2 2 2 2 TPR repeat Ank_2 PF12796.7 RLN82911.1 - 3.5e-07 30.7 0.0 7.6e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TPR_12 PF13424.6 RLN82911.1 - 4.5e-07 30.1 1.2 0.00016 21.9 0.7 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN82911.1 - 1.9e-06 28.2 0.3 0.00012 22.5 0.2 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN82911.1 - 2.1e-06 27.7 0.0 0.022 15.1 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Ank_5 PF13857.6 RLN82911.1 - 2.4e-06 27.7 0.0 0.00018 21.7 0.0 3.0 2 1 1 3 3 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN82911.1 - 4.5e-06 27.1 0.0 1.4e-05 25.5 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) TPR_16 PF13432.6 RLN82911.1 - 4.5e-06 27.2 10.5 0.00066 20.3 0.9 3.8 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN82911.1 - 0.00011 22.7 16.5 0.027 15.3 0.1 5.5 5 1 2 7 7 4 3 Tetratricopeptide repeat Ank PF00023.30 RLN82911.1 - 0.0012 19.2 0.2 0.18 12.3 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat TPR_4 PF07721.14 RLN82911.1 - 0.0018 18.7 0.0 9.5 7.2 0.1 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN82911.1 - 0.0023 18.1 0.0 0.2 11.9 0.0 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Ank_3 PF13606.6 RLN82911.1 - 0.0051 17.2 0.0 0.21 12.3 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat TPR_15 PF13429.6 RLN82911.1 - 0.12 11.6 4.0 0.17 11.1 0.1 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Tnp_zf-ribbon_2 PF13842.6 RLN82911.1 - 1.4 9.8 7.7 3.3 8.6 7.7 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon VHS PF00790.19 RLN82912.1 - 2.2e-14 53.5 0.0 1.1e-13 51.2 0.0 1.8 1 1 1 2 2 2 1 VHS domain GUN4_N PF16416.5 RLN82912.1 - 0.16 12.0 0.1 0.37 10.8 0.1 1.6 1 0 0 1 1 1 0 ARM-like repeat domain, GUN4-N terminal MORN PF02493.20 RLN82913.1 - 1.2e-12 46.9 11.1 0.00014 21.6 0.5 3.8 4 0 0 4 4 4 3 MORN repeat PRA1 PF03208.19 RLN82914.1 - 2.9e-13 49.7 3.9 6.1e-13 48.6 3.8 1.5 1 1 0 1 1 1 1 PRA1 family protein DUF3522 PF12036.8 RLN82915.1 - 0.28 11.5 2.4 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3522) TPR_1 PF00515.28 RLN82916.1 - 7.4e-18 63.5 4.6 3.4e-05 23.5 0.0 5.9 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 RLN82916.1 - 1.5e-14 52.8 2.6 0.012 15.7 0.0 5.8 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 RLN82916.1 - 8.5e-06 26.0 6.4 0.019 15.3 0.1 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN82916.1 - 1.7e-05 24.4 0.2 0.41 10.4 0.2 3.5 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.6 RLN82916.1 - 5.2e-05 23.7 0.1 6 8.0 0.0 4.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN82916.1 - 0.00095 19.6 0.8 0.46 11.0 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN82916.1 - 0.0057 17.3 0.5 1 10.1 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN82916.1 - 0.012 15.7 4.8 40 4.8 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN82916.1 - 0.098 12.9 6.0 0.44 10.8 0.1 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 UPF0242 PF06785.11 RLN82916.1 - 1.5 8.9 9.3 5 7.2 9.3 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TPR_6 PF13174.6 RLN82916.1 - 1.5 9.6 3.8 46 5.0 0.2 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat CHASE3 PF05227.13 RLN82917.1 - 0.0003 20.7 9.1 0.024 14.5 2.4 2.2 1 1 1 2 2 2 2 CHASE3 domain Exonuc_VII_L PF02601.15 RLN82917.1 - 0.012 15.2 3.1 0.014 15.0 3.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FUSC PF04632.12 RLN82917.1 - 0.016 13.8 8.7 0.019 13.5 8.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Atg14 PF10186.9 RLN82917.1 - 0.032 13.3 9.2 0.16 11.0 5.9 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 RLN82917.1 - 0.05 13.7 7.0 0.069 13.3 7.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Tropomyosin PF00261.20 RLN82917.1 - 0.071 12.5 8.7 0.17 11.2 8.7 1.6 1 0 0 1 1 1 0 Tropomyosin MCU PF04678.13 RLN82917.1 - 0.11 12.6 2.3 0.17 12.0 2.3 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter TelA PF05816.11 RLN82917.1 - 0.11 11.6 9.1 0.028 13.5 6.1 1.5 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) LMBR1 PF04791.16 RLN82917.1 - 0.11 11.3 0.3 0.13 11.2 0.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Herpes_UL6 PF01763.16 RLN82917.1 - 0.11 10.9 7.2 0.15 10.5 7.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like V_ATPase_I PF01496.19 RLN82917.1 - 0.12 10.3 1.0 0.12 10.2 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MAT1 PF06391.13 RLN82917.1 - 0.13 12.0 5.5 0.21 11.4 5.5 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Tho2 PF11262.8 RLN82917.1 - 0.17 11.1 4.4 0.29 10.3 4.4 1.4 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 F_actin_bind PF08919.10 RLN82917.1 - 0.19 11.8 6.3 0.12 12.4 4.2 1.7 2 0 0 2 2 1 0 F-actin binding HemX PF04375.14 RLN82917.1 - 0.23 10.7 10.1 0.33 10.2 10.1 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase TMPIT PF07851.13 RLN82917.1 - 0.33 10.1 3.8 0.45 9.7 3.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF334 PF03904.13 RLN82917.1 - 0.37 10.3 2.7 0.53 9.8 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) DUF4509 PF14970.6 RLN82917.1 - 0.38 10.7 7.5 0.11 12.5 3.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4509) DUF4407 PF14362.6 RLN82917.1 - 0.39 10.0 5.5 0.55 9.5 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 RLN82917.1 - 0.49 9.2 8.4 0.7 8.7 8.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein KIAA1430 PF13879.6 RLN82917.1 - 0.53 11.1 9.5 1.1 10.0 9.5 1.5 1 0 0 1 1 1 0 KIAA1430 homologue Jnk-SapK_ap_N PF09744.9 RLN82917.1 - 0.55 10.4 11.3 0.97 9.6 11.3 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 RLN82917.1 - 0.58 10.7 15.9 1.2 9.7 15.6 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region CENP-H PF05837.12 RLN82917.1 - 0.76 10.2 8.2 1.5 9.3 8.2 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DivIC PF04977.15 RLN82917.1 - 0.9 9.4 11.5 0.1 12.4 1.2 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF1664 PF07889.12 RLN82917.1 - 1.1 9.3 4.5 1.3 9.1 2.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-CpG_bind_C PF12269.8 RLN82917.1 - 1.2 8.9 6.4 0.51 10.1 1.0 2.2 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain YlqD PF11068.8 RLN82917.1 - 1.3 9.4 8.9 2.3 8.6 8.9 1.4 1 0 0 1 1 1 0 YlqD protein Macoilin PF09726.9 RLN82917.1 - 2.2 6.7 11.1 3.3 6.2 11.1 1.2 1 0 0 1 1 1 0 Macoilin family DUF4763 PF15960.5 RLN82917.1 - 2.9 7.1 17.1 8.6 5.6 16.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) YabA PF06156.13 RLN82917.1 - 4.1 8.1 9.5 2 9.1 5.2 1.9 1 1 1 2 2 2 0 Initiation control protein YabA LcrG PF07216.12 RLN82917.1 - 4.9 7.1 9.0 7.4 6.6 4.3 2.3 1 1 1 2 2 2 0 LcrG protein ZapB PF06005.12 RLN82917.1 - 7.8 7.0 19.4 7.8 7.0 5.7 2.5 1 1 1 2 2 2 0 Cell division protein ZapB DUF4140 PF13600.6 RLN82917.1 - 7.9 7.0 13.7 7.6 7.0 6.0 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) adh_short PF00106.25 RLN82918.1 - 3.8e-31 108.1 0.0 3e-30 105.1 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN82918.1 - 3.6e-19 69.3 0.0 5.5e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN82918.1 - 2.8e-09 37.1 0.1 4.2e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN82918.1 - 0.00024 20.6 0.4 0.00056 19.4 0.2 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 RLN82918.1 - 0.089 12.0 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 RLN82918.1 - 0.11 11.8 0.2 0.2 11.0 0.1 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_2 PF03446.15 RLN82918.1 - 0.12 12.5 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_transf_4 PF13439.6 RLN82918.1 - 0.13 12.3 1.7 1.2 9.2 1.1 2.3 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 RLN82918.1 - 0.42 11.0 2.8 1.5 9.3 2.8 2.1 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain WD40 PF00400.32 RLN82919.1 - 5.8e-22 77.6 4.0 2.5e-06 28.1 0.2 4.8 4 1 0 4 4 4 4 WD domain, G-beta repeat Sof1 PF04158.14 RLN82919.1 - 0.00027 21.1 4.0 0.00051 20.3 4.0 1.4 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 RLN82919.1 - 0.0004 20.6 0.0 4.3 7.7 0.0 3.6 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain AAA PF00004.29 RLN82920.1 - 1.4e-71 239.1 0.0 1.7e-34 119.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RLN82920.1 - 4.2e-26 90.5 10.6 2e-17 62.7 0.1 3.2 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 RLN82920.1 - 4.6e-11 43.4 5.2 0.0016 18.8 0.0 4.6 3 2 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 RLN82920.1 - 3.1e-07 30.5 0.3 0.05 13.6 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RLN82920.1 - 1.4e-06 28.5 0.0 0.00012 22.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 RLN82920.1 - 7.7e-06 26.2 0.8 0.0012 19.1 0.2 3.7 2 2 1 3 3 3 1 AAA domain DUF815 PF05673.13 RLN82920.1 - 4.1e-05 22.9 0.0 0.13 11.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) RuvB_N PF05496.12 RLN82920.1 - 0.00012 21.9 0.0 0.22 11.3 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 RLN82920.1 - 0.00015 21.7 0.0 0.12 12.2 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_33 PF13671.6 RLN82920.1 - 0.0002 21.5 0.0 0.099 12.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RLN82920.1 - 0.00044 19.8 0.0 0.21 11.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 RLN82920.1 - 0.0027 18.1 0.0 1.6 9.1 0.0 2.9 3 0 0 3 3 2 1 RNA helicase IstB_IS21 PF01695.17 RLN82920.1 - 0.0066 16.2 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein Vps4_C PF09336.10 RLN82920.1 - 0.0066 16.4 0.0 0.33 11.0 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain NACHT PF05729.12 RLN82920.1 - 0.0092 15.9 0.0 0.042 13.8 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 RLN82920.1 - 0.011 15.3 0.2 1.5 8.3 0.1 3.2 2 1 1 3 3 3 0 AAA domain Mg_chelatase PF01078.21 RLN82920.1 - 0.017 14.5 0.1 1 8.7 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 RLN82920.1 - 0.024 13.9 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain NTPase_1 PF03266.15 RLN82920.1 - 0.027 14.4 0.0 0.32 10.9 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.6 RLN82920.1 - 0.038 14.3 0.2 0.52 10.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RLN82920.1 - 0.041 14.4 0.0 0.52 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 RLN82920.1 - 0.044 13.8 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 RLN82920.1 - 0.045 13.5 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 RLN82920.1 - 0.064 13.0 1.1 1.1 8.9 0.0 2.6 3 0 0 3 3 2 0 AAA domain Sigma54_activat PF00158.26 RLN82920.1 - 0.084 12.6 0.0 1.1 8.9 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 RLN82920.1 - 0.084 13.4 0.0 3 8.3 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 RLN82920.1 - 0.15 11.9 0.0 13 5.6 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain cobW PF02492.19 RLN82920.1 - 0.17 11.4 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RecA PF00154.21 RLN82920.1 - 0.2 11.1 0.1 0.61 9.5 0.1 1.8 1 1 0 1 1 1 0 recA bacterial DNA recombination protein Pro_isomerase PF00160.21 RLN82921.1 - 7.8e-37 127.0 0.0 1.3e-36 126.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3328 PF11807.8 RLN82921.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Pro_isomerase PF00160.21 RLN82922.1 - 4.9e-34 117.9 1.1 5.9e-34 117.6 0.0 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SpoIIIAH PF12685.7 RLN82922.1 - 8.3e-05 22.5 1.1 0.00011 22.1 1.1 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein SAPS PF04499.15 RLN82922.1 - 0.028 13.2 0.2 0.03 13.1 0.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 RLN82922.1 - 0.066 12.0 1.1 0.092 11.5 1.1 1.3 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 RLN82922.1 - 0.067 11.4 9.2 0.074 11.3 9.2 1.1 1 0 0 1 1 1 0 Nop14-like family SID-1_RNA_chan PF13965.6 RLN82922.1 - 0.071 11.5 0.1 0.094 11.1 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Spore_coat_CotO PF14153.6 RLN82922.1 - 0.14 12.1 10.1 0.19 11.6 10.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO TERB2 PF15101.6 RLN82922.1 - 0.17 11.9 5.1 0.17 12.0 3.8 1.5 2 0 0 2 2 2 0 Telomere-associated protein TERB2 CDC45 PF02724.14 RLN82922.1 - 0.3 9.3 8.6 0.35 9.1 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 RLN82922.1 - 2.6 8.5 14.6 5.1 7.5 5.2 2.7 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CAS_C PF12026.8 RLN82922.1 - 3.3 7.7 6.2 4.7 7.2 6.2 1.2 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain Borrelia_P83 PF05262.11 RLN82922.1 - 4.7 5.6 12.4 6.4 5.1 12.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PPP4R2 PF09184.11 RLN82922.1 - 9.2 5.8 15.1 13 5.3 15.1 1.1 1 0 0 1 1 1 0 PPP4R2 SNF5 PF04855.12 RLN82923.1 - 0.00015 21.7 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 DprA_WH PF17782.1 RLN82923.1 - 0.049 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 DprA winged helix domain Frataxin_Cyay PF01491.16 RLN82924.1 - 1.8e-10 40.8 0.0 4.1e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 Frataxin-like domain MTCP1 PF08991.10 RLN82926.1 - 1.9e-12 47.2 11.7 4.6e-12 46.0 11.7 1.7 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type COPI_assoc PF08507.10 RLN82926.1 - 0.006 16.6 4.4 0.011 15.7 4.4 1.5 1 0 0 1 1 1 1 COPI associated protein adh_short PF00106.25 RLN82927.1 - 6.6e-30 104.0 0.0 6.6e-30 104.0 0.0 4.1 3 1 1 4 4 4 1 short chain dehydrogenase CAP_GLY PF01302.25 RLN82927.1 - 3.8e-21 74.9 1.1 6.9e-21 74.0 1.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain adh_short_C2 PF13561.6 RLN82927.1 - 8.7e-16 58.2 0.0 8.7e-16 58.2 0.0 3.1 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN82927.1 - 6.9e-06 26.1 0.0 6.9e-06 26.1 0.0 3.9 4 1 1 5 5 5 1 KR domain GHMP_kinases_C PF08544.13 RLN82927.1 - 0.028 14.8 0.0 0.028 14.8 0.0 5.9 5 0 0 5 5 5 0 GHMP kinases C terminal Epimerase PF01370.21 RLN82927.1 - 0.057 12.9 0.0 0.15 11.5 0.0 1.8 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 RLN82927.1 - 1.5 9.0 6.9 0.61 10.2 0.2 3.7 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase ABC_membrane PF00664.23 RLN82976.1 - 2.2e-08 34.1 0.2 2.6e-08 33.9 0.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF981 PF06168.11 RLN82976.1 - 0.014 15.3 0.1 0.019 14.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF5596 PF18082.1 RLN82977.1 - 0.029 14.2 0.0 0.048 13.5 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5596) IMP_cyclohyd PF07826.11 RLN82977.1 - 0.16 11.6 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein Ank_2 PF12796.7 RLN82978.1 - 1.8e-52 175.9 8.8 3.1e-14 53.3 0.2 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN82978.1 - 8.8e-41 137.8 5.7 1.8e-09 37.9 0.1 5.5 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN82978.1 - 3.7e-40 131.3 2.6 0.00012 22.2 0.0 7.6 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 RLN82978.1 - 5.9e-39 130.9 4.0 7.7e-05 23.0 0.0 7.2 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.6 RLN82978.1 - 1.7e-38 130.1 21.4 8.7e-09 35.5 0.4 7.0 1 1 6 7 7 7 7 Ankyrin repeats (many copies) IRK_N PF08466.10 RLN82978.1 - 0.00089 19.4 0.0 4.9 7.4 0.0 3.8 4 0 0 4 4 4 2 Inward rectifier potassium channel N-terminal MEDS PF14417.6 RLN82978.1 - 0.0037 17.1 0.5 0.012 15.5 0.3 1.9 1 1 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain FliT PF05400.13 RLN82978.1 - 0.018 15.8 1.2 0.44 11.4 0.1 3.0 2 2 1 3 3 3 0 Flagellar protein FliT Erythro-docking PF09277.11 RLN82978.1 - 0.071 13.0 1.1 32 4.5 0.0 3.7 4 0 0 4 4 4 0 Erythronolide synthase, docking VWA_3_C PF18571.1 RLN82978.1 - 0.14 12.0 6.9 2.9 7.8 0.1 5.2 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain Spore_III_AB PF09548.10 RLN82979.1 - 0.076 13.1 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) SET PF00856.28 RLN82980.1 - 1.2e-05 25.7 0.5 0.00033 21.1 0.0 2.5 3 0 0 3 3 3 1 SET domain zf-MYND PF01753.18 RLN82980.1 - 7.6e-05 22.7 10.9 7.6e-05 22.7 10.9 2.3 2 0 0 2 2 2 1 MYND finger HD_3 PF13023.6 RLN82980.1 - 0.02 14.8 1.0 0.043 13.7 1.0 1.4 1 0 0 1 1 1 0 HD domain PH PF00169.29 RLN82985.1 - 0.018 15.6 0.0 0.02 15.4 0.0 1.1 1 0 0 1 1 1 0 PH domain Neuroparsin PF07327.11 RLN82985.1 - 0.092 13.2 0.0 0.1 13.1 0.0 1.1 1 0 0 1 1 1 0 Neuroparsin Mlo PF03094.15 RLN82987.1 - 6.8e-06 24.7 4.7 0.0062 15.0 0.5 2.4 1 1 0 2 2 2 2 Mlo family EF-hand_6 PF13405.6 RLN82987.1 - 0.085 12.8 0.0 0.41 10.7 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain DUF16 PF01519.16 RLN82987.1 - 0.11 13.0 0.7 0.35 11.4 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF16 Glyco_hydro_88 PF07470.13 RLN82987.1 - 0.12 11.5 1.0 0.43 9.6 0.1 2.3 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 Sbt_1 PF05982.12 RLN82987.1 - 0.12 11.6 1.3 0.26 10.5 1.3 1.4 1 0 0 1 1 1 0 Na+-dependent bicarbonate transporter superfamily PX PF00787.24 RLN82988.1 - 0.01 15.8 0.1 0.026 14.5 0.1 1.7 1 1 0 1 1 1 0 PX domain NADH5_C PF06455.11 RLN82989.1 - 0.056 13.0 0.0 0.059 13.0 0.0 1.1 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus TMIE PF16038.5 RLN82989.1 - 0.86 9.5 3.3 1 9.3 3.3 1.1 1 0 0 1 1 1 0 TMIE protein Methyltransf_16 PF10294.9 RLN83026.1 - 4.5e-07 29.8 0.0 8.5e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 Lysine methyltransferase Myb_DNA-binding PF00249.31 RLN83027.1 - 1.6e-09 37.8 0.1 2.7e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN83027.1 - 0.0078 16.4 0.1 0.025 14.8 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain V_ATPase_I PF01496.19 RLN83028.1 - 2.4e-167 558.4 0.0 2.7e-167 558.2 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family NAD_Gly3P_dh_N PF01210.23 RLN83029.1 - 1e-18 67.8 0.0 1.1e-18 67.7 0.0 1.0 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AcetDehyd-dimer PF09290.11 RLN83029.1 - 0.12 12.6 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation UvrD_C_2 PF13538.6 RLN83030.1 - 0.0044 16.8 1.4 0.066 13.0 1.4 2.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain PIF1 PF05970.14 RLN83030.1 - 0.012 14.8 0.4 0.053 12.7 0.4 2.0 1 1 1 2 2 2 0 PIF1-like helicase PE-PPE PF08237.11 RLN83030.1 - 0.063 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Sec10 PF07393.11 RLN83031.1 - 0.075 11.4 0.1 0.094 11.1 0.1 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 H2O2_YaaD PF03883.14 RLN83036.1 - 5.3e-77 258.5 0.0 8.3e-77 257.8 0.0 1.3 1 0 0 1 1 1 1 Peroxide stress protein YaaA IRK_C PF17655.1 RLN83037.1 - 1.9e-27 96.0 0.0 8.3e-13 48.3 0.0 2.1 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 RLN83037.1 - 0.00026 20.8 0.1 0.00055 19.8 0.0 1.5 2 0 0 2 2 2 1 Inward rectifier potassium channel transmembrane domain Aminotran_4 PF01063.19 RLN83079.1 - 2.7e-30 105.9 0.0 3.3e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV PI3_PI4_kinase PF00454.27 RLN83081.1 - 4.5e-23 82.4 0.1 6.6e-23 81.8 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GP52 PF17468.2 RLN83081.1 - 0.1 12.8 0.0 3.4 7.9 0.0 2.5 3 0 0 3 3 3 0 Phage gene product 52 Pribosyltran PF00156.27 RLN83082.1 - 2.7e-07 30.2 0.0 3.4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain EF-hand_1 PF00036.32 RLN83083.1 - 6.2e-22 75.5 7.6 6.1e-09 34.8 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 RLN83083.1 - 1.1e-19 68.6 4.8 3e-09 36.1 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 RLN83083.1 - 6e-18 65.1 4.3 6e-14 52.2 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN83083.1 - 4.6e-15 54.3 8.6 8.8e-06 25.0 0.0 3.4 3 0 0 3 3 3 3 EF hand RWP-RK PF02042.15 RLN83083.1 - 2.1e-14 53.2 0.9 9.2e-13 48.0 0.9 3.1 2 1 0 2 2 2 1 RWP-RK domain EF-hand_8 PF13833.6 RLN83083.1 - 1.3e-13 50.6 7.1 6.9e-08 32.2 0.4 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 RLN83083.1 - 0.00059 20.1 0.0 0.15 12.4 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 RLN83083.1 - 0.049 13.6 1.3 2.3 8.2 0.8 2.7 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand DUF4231 PF14015.6 RLN83084.1 - 0.17 12.3 1.1 8 7.0 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DEAD PF00270.29 RLN83085.1 - 3.8e-06 26.8 0.4 0.014 15.2 0.1 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN83085.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.8 1 1 0 1 1 1 0 Helicase conserved C-terminal domain CBS PF00571.28 RLN83085.1 - 0.057 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 CBS domain Pkinase PF00069.25 RLN83086.1 - 1e-45 156.2 0.0 1.3e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN83086.1 - 3.4e-41 141.3 0.0 4.3e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase SKG6 PF08693.10 RLN83086.1 - 0.00032 20.0 1.9 0.00057 19.2 1.9 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain APH PF01636.23 RLN83086.1 - 0.0025 17.8 0.0 0.018 14.9 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Adeno_E3_CR2 PF02439.15 RLN83086.1 - 0.0095 15.7 0.5 0.018 14.8 0.5 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Haspin_kinase PF12330.8 RLN83086.1 - 0.054 12.4 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain CD34_antigen PF06365.12 RLN83086.1 - 0.12 11.9 0.0 0.98 9.0 0.0 2.1 2 0 0 2 2 2 0 CD34/Podocalyxin family Pectate_lyase PF03211.13 RLN83087.1 - 9.8e-23 80.7 0.0 1.3e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Pectate lyase zf-RanBP PF00641.18 RLN83089.1 - 0.0052 16.1 2.3 0.0098 15.2 2.3 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others LRR_4 PF12799.7 RLN83089.1 - 0.035 14.5 1.1 5.2 7.6 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN83089.1 - 0.077 12.8 0.7 0.3 10.9 0.1 2.1 2 0 0 2 2 2 0 Leucine rich repeat tRNA-synt_1g PF09334.11 RLN83131.1 - 2.5e-100 336.0 0.2 9.2e-100 334.1 0.2 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 RLN83131.1 - 2.3e-25 88.9 1.4 4.8e-14 51.5 0.6 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 RLN83131.1 - 5.9e-12 45.5 0.1 4.9e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 RLN83131.1 - 0.046 12.6 0.0 0.12 11.3 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (K) Pkinase_Tyr PF07714.17 RLN83132.1 - 4.9e-50 170.2 0.0 5.9e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN83132.1 - 2.2e-48 164.9 0.0 2.7e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 RLN83132.1 - 0.0064 15.9 0.0 0.0097 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN83132.1 - 0.016 15.1 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Syndecan PF01034.20 RLN83132.1 - 0.025 14.5 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Phage_T7_Capsid PF05396.11 RLN83132.1 - 0.18 12.2 0.0 0.78 10.1 0.0 1.9 2 0 0 2 2 2 0 Phage T7 capsid assembly protein SP_C-Propep PF08999.10 RLN83132.1 - 0.34 10.7 4.1 0.79 9.5 4.1 1.6 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Sec62 PF03839.16 RLN83132.1 - 0.65 9.5 1.7 0.98 8.9 1.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 GAF_2 PF13185.6 RLN83133.1 - 6.4e-14 52.4 0.2 5.1e-05 23.6 0.0 4.9 4 0 0 4 4 4 2 GAF domain EF-hand_7 PF13499.6 RLN83133.1 - 1.2e-09 38.5 0.1 8.1e-09 35.8 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 RLN83133.1 - 2.2e-05 24.2 0.9 0.00057 19.7 0.0 3.3 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN83133.1 - 0.0018 17.7 0.2 0.011 15.2 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RLN83133.1 - 0.0032 17.3 0.0 0.8 9.8 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 RLN83133.1 - 0.055 13.0 0.0 0.86 9.2 0.0 2.6 2 0 0 2 2 2 0 EF hand IQ PF00612.27 RLN83133.1 - 0.4 10.6 24.2 5.6 7.0 2.6 4.5 3 0 0 3 3 3 0 IQ calmodulin-binding motif DUF1336 PF07059.12 RLN83134.1 - 4.3e-30 105.5 0.0 2.3e-29 103.1 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1336) PH PF00169.29 RLN83134.1 - 6.1e-07 29.9 0.0 1.2e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN83134.1 - 0.007 16.6 0.0 0.041 14.2 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 RLN83134.1 - 0.17 12.3 0.2 0.35 11.3 0.2 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain FAM117 PF15388.6 RLN83134.1 - 2.6 7.4 8.3 4.1 6.8 8.3 1.2 1 0 0 1 1 1 0 Protein Family FAM117 SIS PF01380.22 RLN83136.1 - 2.7e-30 104.9 0.2 2.1e-16 60.0 0.0 2.5 2 1 0 2 2 2 2 SIS domain GRIP PF01465.20 RLN83137.1 - 1.9e-15 56.5 0.0 4.9e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 GRIP domain DUF5343 PF17278.2 RLN83137.1 - 5.1 7.2 8.2 0.63 10.1 0.3 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5343) PH PF00169.29 RLN83138.1 - 6.1e-37 126.3 0.1 5.9e-06 26.7 0.0 7.5 7 0 0 7 7 7 7 PH domain PDZ_6 PF17820.1 RLN83138.1 - 3.2e-06 26.9 0.0 1.2e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PH_11 PF15413.6 RLN83138.1 - 4.5e-06 27.0 1.5 1.2 9.6 0.0 5.6 6 1 0 6 6 6 2 Pleckstrin homology domain PDZ PF00595.24 RLN83138.1 - 5.9e-06 26.5 0.0 1.5e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 RLN83139.1 - 1.8e-09 38.0 0.1 3.4e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN83139.1 - 0.001 19.3 0.1 0.0017 18.6 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 RLN83139.1 - 0.02 15.3 4.8 7.5 7.0 4.8 2.7 1 1 0 1 1 1 0 Pleckstrin homology domain DUF4551 PF15087.6 RLN83139.1 - 0.053 12.4 10.8 0.057 12.3 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pol_alpha_B_N PF08418.10 RLN83139.1 - 2.1 8.3 12.1 2.9 7.8 12.1 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal PAT1 PF09770.9 RLN83139.1 - 4.1 5.5 8.6 5 5.3 8.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Apt1 PF10351.9 RLN83139.1 - 5.8 5.6 13.0 6.9 5.4 13.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain cNMP_binding PF00027.29 RLN83140.1 - 5.7e-15 55.2 0.0 1.9e-09 37.5 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN83140.1 - 4.4e-08 32.7 15.2 2.4e-07 30.2 8.6 2.3 2 0 0 2 2 2 2 Ion transport protein C2 PF00168.30 RLN83141.1 - 1.1e-18 67.4 0.3 2e-18 66.5 0.0 1.6 2 0 0 2 2 2 1 C2 domain Pex24p PF06398.11 RLN83141.1 - 5e-06 25.7 6.7 9.1e-06 24.9 6.7 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin FYVE PF01363.21 RLN83141.1 - 2.5e-05 24.3 1.0 0.019 15.1 0.2 2.5 2 0 0 2 2 2 2 FYVE zinc finger PRT_C PF08372.10 RLN83141.1 - 0.005 16.6 7.7 0.17 11.7 1.3 2.4 2 0 0 2 2 2 2 Plant phosphoribosyltransferase C-terminal DUF639 PF04842.12 RLN83141.1 - 0.075 12.4 8.6 0.9 8.9 0.3 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) Pkinase_Tyr PF07714.17 RLN83142.1 - 7.3e-15 55.0 0.0 1e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN83142.1 - 1e-12 48.0 0.0 1.3e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain BatD PF13584.6 RLN83142.1 - 0.066 12.0 0.0 0.088 11.6 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF1180 PF06679.12 RLN83142.1 - 0.075 13.4 1.4 0.12 12.8 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Trp_oprn_chp PF09534.10 RLN83142.1 - 0.16 11.8 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Macoilin PF09726.9 RLN83142.1 - 1.1 7.7 4.8 1.3 7.5 4.8 1.1 1 0 0 1 1 1 0 Macoilin family Glyco_hydro_5_C PF18564.1 RLN83184.1 - 5.9e-15 55.6 0.6 2.3e-14 53.7 0.6 2.1 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain OrfB_Zn_ribbon PF07282.11 RLN83184.1 - 0.0058 16.5 0.2 0.016 15.1 0.2 1.7 1 0 0 1 1 1 1 Putative transposase DNA-binding domain DUF3349 PF11829.8 RLN83184.1 - 0.091 13.6 0.1 0.26 12.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) Herpes_BLLF1 PF05109.13 RLN83186.1 - 0.063 11.3 26.6 0.095 10.7 26.6 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Mucin PF01456.17 RLN83186.1 - 0.25 11.3 31.9 0.036 14.0 27.4 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Shisa PF13908.6 RLN83186.1 - 1.3 9.2 7.6 0.13 12.5 3.3 1.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF4744 PF15918.5 RLN83186.1 - 8 7.4 6.7 32 5.5 6.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4744) Mucin PF01456.17 RLN83188.1 - 1 9.3 40.9 0.3 11.1 35.2 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein ELMO_CED12 PF04727.13 RLN83190.1 - 1.9e-20 73.7 0.0 3.2e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family EGF_2 PF07974.13 RLN83192.1 - 3.4e-15 56.1 64.8 2e-05 24.9 9.2 5.6 5 1 0 5 5 5 5 EGF-like domain Laminin_EGF PF00053.24 RLN83192.1 - 0.037 14.2 6.0 0.037 14.2 6.0 4.9 4 3 1 5 5 5 0 Laminin EGF domain AAA_26 PF13500.6 RLN83235.1 - 3e-23 82.7 0.0 6.2e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain COG4 PF08318.12 RLN83235.1 - 0.18 10.9 0.4 0.31 10.1 0.1 1.4 2 0 0 2 2 2 0 COG4 transport protein SET PF00856.28 RLN83236.1 - 7.4e-13 49.2 0.0 1.3e-12 48.4 0.0 1.6 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 RLN83236.1 - 0.00018 21.5 11.3 0.00018 21.5 11.3 3.5 3 1 0 3 3 3 1 MYND finger zf-Mss51 PF13824.6 RLN83236.1 - 0.49 10.5 16.0 6 7.1 4.0 3.9 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 PTEN_C2 PF10409.9 RLN83237.1 - 9.2e-09 35.2 0.0 1.3e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 RLN83237.1 - 0.00027 20.8 0.0 0.00062 19.6 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 RLN83237.1 - 0.019 14.9 0.0 0.019 14.9 0.0 1.9 3 0 0 3 3 3 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 RLN83237.1 - 0.081 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Nucleo_P87 PF07267.11 RLN83237.1 - 0.92 8.3 4.5 1.8 7.3 4.5 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Glyco_hydro_9 PF00759.19 RLN83237.1 - 8.1 5.8 13.8 0.26 10.7 7.7 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 9 Peptidase_S9_N PF02897.15 RLN83240.1 - 2.2e-110 369.3 0.0 3.2e-110 368.8 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 RLN83240.1 - 1.7e-59 200.8 0.0 3.5e-59 199.8 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DIX PF00778.17 RLN83240.1 - 0.026 14.4 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 DIX domain BAAT_C PF08840.11 RLN83240.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal cNMP_binding PF00027.29 RLN83242.1 - 7.8e-26 90.0 0.1 3.3e-13 49.5 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF5435 PF17503.2 RLN83242.1 - 0.029 14.1 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5435) Ion_trans PF00520.31 RLN83242.1 - 0.043 13.0 3.0 0.18 11.0 3.0 1.9 1 1 0 1 1 1 0 Ion transport protein Ion_trans_2 PF07885.16 RLN83242.1 - 0.12 12.3 0.4 0.33 11.0 0.4 1.7 1 0 0 1 1 1 0 Ion channel GCV_T PF01571.21 RLN83243.1 - 6.6e-81 271.5 0.0 1e-80 270.8 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 RLN83243.1 - 3.2e-21 75.0 0.4 6.8e-21 74.0 0.4 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SPOB_ab PF14682.6 RLN83243.1 - 0.043 13.9 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal tRNA-synt_1 PF00133.22 RLN83285.1 - 8.6e-59 199.3 0.1 8.9e-41 139.8 2.4 6.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 RLN83285.1 - 6e-53 179.1 0.0 8.7e-53 178.6 0.0 1.2 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 RLN83285.1 - 1.5e-25 89.8 0.0 9.2e-20 70.7 0.0 3.9 3 1 1 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 RLN83285.1 - 7.6e-13 48.7 0.0 2.1e-12 47.2 0.0 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 RLN83285.1 - 0.066 12.5 0.0 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Lar_restr_allev PF14354.6 RLN83285.1 - 0.22 11.9 1.0 2.1 8.8 0.7 2.5 2 0 0 2 2 2 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.10 RLN83285.1 - 0.33 11.1 3.0 2.3 8.4 0.4 2.6 2 0 0 2 2 2 0 Zinc ribbon domain DNA_ligase_ZBD PF03119.16 RLN83285.1 - 0.88 9.7 7.2 1.2 9.3 0.0 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Glyco_hydro_28 PF00295.17 RLN83286.1 - 1.5e-74 251.0 17.8 1.5e-74 251.0 17.8 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 Methyltransf_11 PF08241.12 RLN83287.1 - 2e-12 47.6 0.1 8.2e-12 45.6 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN83287.1 - 6.7e-09 36.4 0.1 2.1e-07 31.6 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN83287.1 - 8.7e-09 35.4 0.0 1.6e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN83287.1 - 1.1e-08 35.7 0.1 2.3e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 RLN83287.1 - 1.3e-06 28.3 0.2 0.0033 17.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 RLN83287.1 - 0.014 14.7 0.0 0.041 13.2 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_7 PF03492.15 RLN83287.1 - 0.16 11.1 0.1 0.16 11.1 0.1 1.7 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase vATP-synt_AC39 PF01992.16 RLN83288.1 - 5.7e-92 308.8 0.0 1.2e-90 304.4 0.0 2.0 1 1 0 1 1 1 1 ATP synthase (C/AC39) subunit Coilin_N PF15862.5 RLN83290.1 - 1.9 8.3 5.4 0.52 10.1 0.7 2.2 2 0 0 2 2 2 0 Coilin N-terminus kleA_kleC PF17383.2 RLN83324.1 - 0.087 13.2 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A UCH PF00443.29 RLN83326.1 - 8e-73 245.1 0.0 9.9e-73 244.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 RLN83326.1 - 6.5e-19 68.3 0.0 1.4e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 RLN83326.1 - 1.9e-13 50.7 0.0 4e-07 29.9 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-MYND PF01753.18 RLN83326.1 - 1.8e-09 37.5 11.9 1.8e-09 37.5 11.9 2.9 3 0 0 3 3 3 1 MYND finger PAP_central PF04928.17 RLN83328.1 - 9.5e-70 234.4 0.0 1.3e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 RLN83328.1 - 1.7e-06 27.7 0.0 6.4e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain Nrap_D2 PF17403.2 RLN83328.1 - 0.0016 18.2 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain NTP_transf_2 PF01909.23 RLN83328.1 - 0.22 11.9 0.0 0.69 10.2 0.0 1.8 1 1 0 1 1 1 0 Nucleotidyltransferase domain Pkinase PF00069.25 RLN83329.1 - 5.8e-65 219.3 0.0 9.7e-64 215.3 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN83329.1 - 1.6e-31 109.6 0.0 7.9e-25 87.6 0.0 3.2 3 1 0 3 3 3 2 Protein tyrosine kinase SnoaL_2 PF12680.7 RLN83329.1 - 6.9e-09 36.3 0.1 2.5e-08 34.5 0.1 2.0 1 0 0 1 1 1 1 SnoaL-like domain PH PF00169.29 RLN83329.1 - 4.7e-05 23.8 0.0 9.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF4440 PF14534.6 RLN83329.1 - 0.02 15.3 0.0 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) Haspin_kinase PF12330.8 RLN83329.1 - 0.19 10.6 0.1 0.33 9.9 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain NUDIX PF00293.28 RLN83330.1 - 2.4e-07 30.9 1.1 2.6e-06 27.5 1.2 2.2 1 1 1 2 2 2 1 NUDIX domain Macoilin PF09726.9 RLN83331.1 - 4.5 5.7 12.7 5.6 5.4 12.7 1.2 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 RLN83332.1 - 1.7e-13 51.2 2.6 6.9e-08 32.8 0.1 2.7 3 0 0 3 3 3 2 SPX domain zf-RING_UBOX PF13445.6 RLN83332.1 - 2.9e-06 27.2 9.6 5.2e-06 26.4 9.6 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 RLN83332.1 - 3.1e-06 27.4 13.5 5.9e-06 26.5 13.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RLN83332.1 - 7.4e-06 25.7 12.0 1.4e-05 24.9 12.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN83332.1 - 2.7e-05 23.9 10.9 4.5e-05 23.2 10.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RLN83332.1 - 0.00012 22.2 12.0 0.00023 21.3 12.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 RLN83332.1 - 0.00028 20.7 13.0 0.0005 19.9 13.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN83332.1 - 0.00039 20.3 11.6 0.00096 19.1 11.7 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RLN83332.1 - 0.0041 16.9 14.3 0.022 14.6 14.6 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Metallophos PF00149.28 RLN83332.1 - 0.0058 17.1 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GatD_N PF18195.1 RLN83332.1 - 0.17 11.2 0.1 0.32 10.3 0.1 1.4 1 0 0 1 1 1 0 GatD N-terminal domain zf-RING_4 PF14570.6 RLN83332.1 - 0.21 11.4 8.4 0.66 9.8 8.4 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 RLN83332.1 - 0.33 11.3 10.3 0.67 10.3 10.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 RLN83332.1 - 0.79 9.9 5.5 1.7 8.9 5.5 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_5 PF17121.5 RLN83332.1 - 3.6 7.6 6.4 8.1 6.4 6.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Peptidase_M13_N PF05649.13 RLN83333.1 - 6.8e-81 272.9 0.0 9.7e-81 272.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 RLN83333.1 - 4.9e-65 219.0 0.1 6.9e-65 218.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.18 RLN83333.1 - 0.092 12.5 0.1 0.59 9.9 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M48 DHHC PF01529.20 RLN83334.1 - 1.6e-26 93.0 13.2 1.6e-26 93.0 13.2 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 RLN83334.1 - 7.3e-25 87.4 3.1 6.8e-09 36.2 0.0 4.1 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN83334.1 - 6.4e-22 77.6 2.9 1.5e-06 28.6 0.2 4.8 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN83334.1 - 4.9e-21 72.6 0.6 0.00061 20.1 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 RLN83334.1 - 8.3e-18 64.2 5.1 3.2e-05 24.1 0.0 5.5 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN83334.1 - 6.3e-11 42.2 8.2 0.00012 22.4 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat DUF4231 PF14015.6 RLN83334.1 - 0.082 13.4 1.8 0.16 12.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) BAH PF01426.18 RLN83335.1 - 3.9e-15 55.8 0.4 3.9e-15 55.8 0.4 1.5 2 0 0 2 2 2 1 BAH domain ELM2 PF01448.24 RLN83335.1 - 0.0002 22.1 0.1 0.00058 20.6 0.1 1.8 1 0 0 1 1 1 1 ELM2 domain Peptidase_S9_N PF02897.15 RLN83336.1 - 2.8e-86 289.9 6.6 3.9e-86 289.5 6.6 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 RLN83336.1 - 2.9e-65 219.7 0.1 2.1e-64 216.9 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF4795 PF16043.5 RLN83387.1 - 1.4 8.5 4.5 1.9 8.1 3.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) SlyX PF04102.12 RLN83388.1 - 0.022 15.3 0.8 0.022 15.3 0.8 3.6 2 1 1 3 3 3 0 SlyX Utp11 PF03998.13 RLN83388.1 - 0.13 12.2 9.3 0.17 11.8 9.3 1.1 1 0 0 1 1 1 0 Utp11 protein DUF3391 PF11871.8 RLN83388.1 - 1.6 9.3 17.5 0.032 14.8 8.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) V_ATPase_I PF01496.19 RLN83388.1 - 2.2 6.1 8.3 2.8 5.7 8.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RabGAP-TBC PF00566.18 RLN83389.1 - 0.0002 21.1 0.8 0.00043 20.0 0.2 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF456 PF04306.13 RLN83392.1 - 7.8 6.8 8.7 0.19 12.0 1.3 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF456) zf-CCHC PF00098.23 RLN83394.1 - 9.9e-07 28.6 4.1 2e-06 27.6 4.1 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 RLN83394.1 - 1.2e-06 28.3 0.0 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_5 PF14787.6 RLN83394.1 - 0.0004 20.0 0.7 0.00086 19.0 0.7 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 RLN83394.1 - 0.034 14.1 0.6 0.087 12.8 0.6 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 RLN83394.1 - 0.11 12.4 1.6 0.23 11.3 1.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotran_gag_3 PF14244.6 RLN83394.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RGS-like PF09128.11 RLN83394.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain U-box PF04564.15 RLN83421.1 - 1.7e-21 76.2 0.0 2.5e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 U-box domain COMM_domain PF07258.14 RLN83422.1 - 3e-16 59.3 0.0 4.5e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 COMM domain Enkurin PF13864.6 RLN83423.1 - 6.7e-25 87.4 0.9 1e-24 86.8 0.9 1.3 1 0 0 1 1 1 1 Calmodulin-binding MscS_porin PF12795.7 RLN83423.1 - 0.14 11.7 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Pkinase PF00069.25 RLN83424.1 - 5.4e-52 176.7 0.0 7.2e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN83424.1 - 3.6e-45 154.3 0.0 4.9e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TMEM154 PF15102.6 RLN83424.1 - 0.00078 19.4 0.1 0.00078 19.4 0.1 2.4 2 0 0 2 2 2 1 TMEM154 protein family DUF347 PF03988.12 RLN83424.1 - 0.012 15.7 0.2 0.03 14.5 0.2 1.6 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) APH PF01636.23 RLN83424.1 - 0.021 14.7 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN83424.1 - 0.027 13.4 0.0 0.085 11.8 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Herpes_gE PF02480.16 RLN83424.1 - 0.043 12.6 0.1 0.066 11.9 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 RLN83424.1 - 0.055 14.4 0.0 0.13 13.2 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 RLN83424.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Amnionless Podoplanin PF05808.11 RLN83424.1 - 1.5 8.9 19.2 10 6.2 19.2 2.1 1 1 0 1 1 1 0 Podoplanin Ank_2 PF12796.7 RLN83425.1 - 2.3e-40 137.1 1.6 2.8e-08 34.2 0.1 7.0 3 1 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN83425.1 - 6e-35 119.2 13.4 3.4e-06 27.5 0.0 10.2 8 2 3 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN83425.1 - 1.2e-28 98.8 19.4 0.0023 18.2 0.0 12.8 4 2 10 14 14 14 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN83425.1 - 6.2e-25 84.6 5.1 0.63 10.8 0.1 14.6 11 3 5 16 16 16 4 Ankyrin repeat DUF5049 PF16468.5 RLN83425.1 - 1.7e-05 24.6 0.0 44 4.1 0.0 7.0 3 2 3 6 6 6 0 Domain of unknown function (DUF5049) Ank PF00023.30 RLN83425.1 - 6.7e-05 23.2 3.3 70 4.1 0.1 8.2 8 3 0 8 8 8 0 Ankyrin repeat Helicase_PWI PF18149.1 RLN83425.1 - 0.0021 18.2 0.0 4.3 7.5 0.0 3.3 3 1 0 3 3 3 2 N-terminal helicase PWI domain DUF1843 PF08898.10 RLN83425.1 - 0.0081 16.6 0.1 1.2e+02 3.3 0.0 5.6 6 0 0 6 6 6 0 Domain of unknown function (DUF1843) Ank_2 PF12796.7 RLN83426.1 - 1.5e-36 124.9 11.4 5.8e-10 39.6 0.3 6.8 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN83426.1 - 1.9e-33 114.0 26.9 0.0021 18.4 0.1 15.4 4 2 12 16 16 16 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN83426.1 - 1.8e-32 111.3 17.4 3.4e-06 27.5 0.2 10.5 8 3 1 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN83426.1 - 4.2e-20 69.7 12.1 2.5 9.0 0.0 13.5 12 1 3 15 15 15 5 Ankyrin repeat Ank PF00023.30 RLN83426.1 - 3.4e-05 24.1 4.6 53 4.5 0.0 9.6 6 3 3 9 9 9 0 Ankyrin repeat DUF5049 PF16468.5 RLN83426.1 - 4.1e-05 23.4 0.2 37 4.3 0.0 6.9 4 3 4 8 8 8 0 Domain of unknown function (DUF5049) CNOT1_HEAT PF16418.5 RLN83426.1 - 0.0099 16.0 3.2 4.1 7.5 0.0 5.6 5 3 2 7 7 7 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF249 PF03158.13 RLN83426.1 - 0.3 10.8 4.3 41 3.8 0.1 4.4 3 2 0 4 4 4 0 Multigene family 530 protein Peptidase_M14 PF00246.24 RLN83427.1 - 1.2e-43 150.0 0.0 1.9e-43 149.4 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Trp_oprn_chp PF09534.10 RLN83427.1 - 0.003 17.4 2.4 0.019 14.7 0.4 2.5 3 0 0 3 3 3 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MFS_1 PF07690.16 RLN83427.1 - 0.052 12.5 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF4381 PF14316.6 RLN83427.1 - 0.14 12.4 0.2 0.14 12.4 0.2 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Glyco_hydro_16 PF00722.21 RLN83427.1 - 0.16 11.4 0.3 0.37 10.3 0.3 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 Gram_pos_anchor PF00746.21 RLN83427.1 - 1.9 8.5 3.6 4.4 7.3 3.6 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif MFS_1 PF07690.16 RLN83429.1 - 2.6e-24 85.8 33.6 2.6e-24 85.8 33.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Orai-1 PF07856.12 RLN83429.1 - 0.27 10.9 0.1 0.27 10.9 0.1 2.7 3 0 0 3 3 3 0 Mediator of CRAC channel activity Rieske PF00355.26 RLN83430.1 - 1.6e-08 34.4 0.3 3.6e-08 33.2 0.2 1.6 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 RLN83430.1 - 1e-07 31.8 0.0 1.3e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain zf-TAZ PF02135.16 RLN83431.1 - 6.5e-09 36.1 13.5 6.5e-09 36.1 13.5 3.8 3 2 0 3 3 3 2 TAZ zinc finger SAGA-Tad1 PF12767.7 RLN83431.1 - 3.6e-06 26.9 0.9 3.6e-06 26.9 0.9 2.8 3 0 0 3 3 3 1 Transcriptional regulator of RNA polII, SAGA, subunit Pkinase PF00069.25 RLN83432.1 - 1.5e-36 126.1 0.0 2.2e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN83432.1 - 3.2e-18 66.0 0.0 4.2e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN83432.1 - 2.5e-06 27.0 0.0 3.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN83432.1 - 0.0094 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MetW PF07021.12 RLN83432.1 - 0.064 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW LRR_6 PF13516.6 RLN83433.1 - 1.8e-17 61.9 6.0 2.8e-05 23.8 0.1 5.3 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 RLN83433.1 - 0.0072 16.7 0.9 71 4.6 0.1 4.3 4 1 0 4 4 4 1 Leucine Rich Repeat Hydrolase PF00702.26 RLN83434.1 - 9.8e-41 140.3 1.7 1.7e-40 139.6 1.7 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RLN83434.1 - 9.7e-40 136.0 2.1 2.1e-39 134.9 2.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 RLN83434.1 - 6.3e-10 39.3 0.0 4e-08 33.6 0.0 3.1 2 1 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 RLN83434.1 - 4.1e-06 26.7 0.0 0.0011 18.7 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 RLN83434.1 - 0.00015 22.3 0.1 0.00042 20.8 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FAP206 PF12018.8 RLN83435.1 - 1.6e-09 37.7 0.1 0.0072 15.9 0.0 4.7 5 0 0 5 5 5 2 Domain of unknown function AAA PF00004.29 RLN83435.1 - 2.7e-06 27.9 0.0 0.044 14.2 0.0 3.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN83435.1 - 2.4e-05 24.6 0.1 2.8 8.2 0.0 3.9 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 RLN83435.1 - 6e-05 23.6 0.0 0.15 12.6 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.6 RLN83435.1 - 0.00018 22.0 23.1 0.073 13.4 0.1 5.4 4 2 0 4 4 4 3 AAA ATPase domain YHS PF04945.13 RLN83435.1 - 0.00019 21.5 0.2 0.97 9.6 0.5 4.4 5 0 0 5 5 5 1 YHS domain IstB_IS21 PF01695.17 RLN83435.1 - 0.0011 18.7 0.0 0.32 10.7 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein Hydin_ADK PF17213.3 RLN83435.1 - 0.0016 18.7 4.8 0.2 11.9 0.0 3.9 3 0 0 3 3 3 1 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 RLN83435.1 - 0.0021 18.2 8.0 0.38 10.9 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_5 PF07728.14 RLN83435.1 - 0.0057 16.6 0.1 14 5.6 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 RLN83435.1 - 0.024 15.1 0.0 5.3 7.5 0.0 3.3 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 RLN83435.1 - 0.031 14.4 0.8 13 5.9 0.0 3.6 3 1 0 3 3 3 0 Shikimate kinase Zeta_toxin PF06414.12 RLN83435.1 - 0.07 12.4 0.0 18 4.5 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin TFIIA PF03153.13 RLN83435.1 - 0.51 10.3 6.7 5.3 6.9 1.6 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit GTP1_OBG PF01018.22 RLN83436.1 - 1.8e-16 60.1 6.0 2.7e-16 59.6 6.0 1.2 1 0 0 1 1 1 1 GTP1/OBG Sigma70_ner PF04546.13 RLN83436.1 - 0.002 18.0 2.5 0.0026 17.7 2.5 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region YL1 PF05764.13 RLN83436.1 - 0.016 15.3 6.4 0.02 15.0 6.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 RLN83436.1 - 0.022 13.1 5.4 0.027 12.8 5.4 1.0 1 0 0 1 1 1 0 CDC45-like protein BNIP2 PF12496.8 RLN83436.1 - 0.028 14.9 7.8 0.037 14.5 7.8 1.1 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 SDA1 PF05285.12 RLN83436.1 - 0.25 10.7 12.0 0.3 10.5 12.0 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RLN83436.1 - 0.31 9.2 8.8 0.36 9.0 8.8 1.0 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L6e PF01159.19 RLN83437.1 - 1.4e-33 115.8 0.7 1.4e-33 115.8 0.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L6e Pkinase PF00069.25 RLN83438.1 - 5.6e-69 232.4 0.0 3e-68 230.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN83438.1 - 2.3e-27 95.9 0.0 3.6e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase MMR_HSR1 PF01926.23 RLN83438.1 - 4.4e-22 78.3 0.0 1.4e-21 76.7 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 RLN83438.1 - 2.2e-14 53.3 0.0 4.8e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 GTP1/OBG FeoB_N PF02421.18 RLN83438.1 - 1.9e-06 27.5 0.0 5.1e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 RLN83438.1 - 0.061 12.7 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 RLN83438.1 - 0.15 12.6 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Pox_ser-thr_kin PF05445.11 RLN83438.1 - 0.25 10.2 0.0 0.47 9.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cauli_VI PF01693.16 RLN83551.1 - 3e-47 158.7 15.2 1.6e-17 63.5 1.5 3.6 3 0 0 3 3 3 3 Caulimovirus viroplasmin RNase_H PF00075.24 RLN83551.1 - 2.6e-26 92.5 0.0 5.1e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 RNase H RimM PF01782.18 RLN83551.1 - 0.094 12.9 0.2 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 RimM N-terminal domain MMR_HSR1 PF01926.23 RLN83552.1 - 0.0004 20.4 0.0 0.0013 18.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RLN83552.1 - 0.0039 17.6 0.2 0.02 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 RLN83552.1 - 0.013 16.0 0.0 0.042 14.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 RLN83552.1 - 0.024 14.8 0.0 0.08 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 RLN83552.1 - 0.037 14.3 0.2 0.19 12.0 0.0 2.3 2 1 1 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 RLN83552.1 - 0.053 13.4 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 RsgA GTPase T2SSE PF00437.20 RLN83552.1 - 0.058 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 RLN83552.1 - 0.13 11.6 0.2 0.31 10.3 0.2 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF87 PF01935.17 RLN83552.1 - 0.14 12.2 0.1 0.34 11.0 0.1 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_18 PF13238.6 RLN83552.1 - 0.15 12.6 0.0 0.41 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Collagen PF01391.18 RLN83552.1 - 2.5 7.9 10.3 0.74 9.6 2.3 2.3 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Pro_isomerase PF00160.21 RLN83604.1 - 2.2e-24 86.5 0.9 9.1e-21 74.8 0.4 2.5 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SpoIIE PF07228.12 RLN83605.1 - 3.3e-08 33.7 0.1 5.7e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 RLN83605.1 - 1.2e-07 31.6 0.4 2.3e-07 30.7 0.4 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C DUF2985 PF11204.8 RLN83606.1 - 4.9e-12 45.8 1.7 1e-11 44.8 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Sdh_cyt PF01127.22 RLN83606.1 - 0.017 15.1 2.3 0.037 14.1 2.3 1.5 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2368 PF10166.9 RLN83606.1 - 0.18 11.4 0.5 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) DUF3341 PF11821.8 RLN83606.1 - 2.4 7.8 4.4 1.2 8.8 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Peptidase_S10 PF00450.22 RLN83642.1 - 5.8e-53 180.8 0.0 7.8e-53 180.4 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase EF-hand_6 PF13405.6 RLN83643.1 - 1.4e-12 46.5 7.0 0.0057 16.5 0.1 4.9 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 RLN83643.1 - 1.3e-11 43.2 6.0 0.0081 15.6 0.1 4.9 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 RLN83643.1 - 8.4e-08 31.4 7.1 0.066 12.7 0.2 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 RLN83643.1 - 1.4e-07 31.9 11.0 0.00095 19.6 0.1 4.0 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.6 RLN83643.1 - 0.0011 18.7 6.8 0.16 11.8 0.2 4.4 4 0 0 4 4 4 1 EF-hand domain pair FMN_bind PF04205.14 RLN83643.1 - 0.098 13.2 0.1 19 5.9 0.2 3.3 2 1 0 2 2 2 0 FMN-binding domain YCII PF03795.14 RLN83644.1 - 4.4e-10 39.8 0.0 5.4e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain DUF4636 PF15468.6 RLN83645.1 - 9.6 5.8 8.5 16 5.1 8.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) DUF5575 PF17738.1 RLN83688.1 - 0.00066 18.8 0.1 0.016 14.3 0.0 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5575) MULE PF10551.9 RLN83688.1 - 0.0012 19.2 0.0 0.0028 18.0 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 RLN83688.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Transposase Porin_3 PF01459.22 RLN83689.1 - 5.5e-09 35.9 0.0 8.9e-09 35.2 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic porin adh_short_C2 PF13561.6 RLN83690.1 - 2.2e-57 194.3 5.4 2.5e-57 194.1 5.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RLN83690.1 - 2.2e-49 167.6 2.7 2.6e-49 167.3 2.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RLN83690.1 - 7.3e-12 45.6 2.3 1.3e-11 44.8 2.3 1.4 1 0 0 1 1 1 1 KR domain Seadorna_Vp10 PF07322.11 RLN83690.1 - 0.18 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus Vp10 DEAD PF00270.29 RLN83691.1 - 1.4e-48 165.0 0.0 2.4e-47 161.0 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN83691.1 - 1.2e-32 112.5 0.0 3.5e-32 111.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN83691.1 - 0.0031 17.5 0.0 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Ysc84 PF04366.12 RLN83692.1 - 4e-35 120.4 0.6 7.7e-35 119.4 0.6 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator FYVE PF01363.21 RLN83692.1 - 1.2e-11 44.6 10.7 1.2e-11 44.6 10.7 2.8 3 0 0 3 3 3 1 FYVE zinc finger HypA PF01155.19 RLN83692.1 - 0.22 11.6 10.6 0.12 12.4 1.5 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SPX PF03105.19 RLN83692.1 - 5.2 6.9 9.0 6.9 6.5 2.6 2.1 2 0 0 2 2 2 0 SPX domain Zn_Tnp_IS1595 PF12760.7 RLN83692.1 - 6.2 6.9 14.5 0.038 14.0 2.0 2.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Lactonase PF10282.9 RLN83693.1 - 4.9e-87 292.4 0.0 5.6e-87 292.2 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Lipase_C PF18067.1 RLN83693.1 - 0.019 15.5 0.0 8.7 7.0 0.0 2.9 2 0 0 2 2 2 0 Lipase C-terminal domain ASH PF15780.5 RLN83695.1 - 2.4e-22 78.9 4.8 7.4e-06 26.1 0.0 8.3 8 1 0 8 8 8 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin LRR_6 PF13516.6 RLN83695.1 - 3.4e-14 51.6 2.7 0.0074 16.3 0.0 5.7 5 0 0 5 5 5 3 Leucine Rich repeat PapD-like PF14874.6 RLN83695.1 - 5.3e-08 32.9 0.1 0.0032 17.6 0.0 6.0 7 0 0 7 7 7 1 Flagellar-associated PapD-like LRR_4 PF12799.7 RLN83695.1 - 0.0037 17.6 0.6 0.12 12.9 0.1 3.0 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) TMEM131_like PF12371.8 RLN83695.1 - 0.0048 17.1 0.0 2.8 8.3 0.0 3.8 4 0 0 4 4 4 1 Transmembrane protein 131-like LRR_8 PF13855.6 RLN83695.1 - 0.48 10.2 3.2 3.3 7.6 0.3 3.1 2 1 1 3 3 3 0 Leucine rich repeat TMEM192 PF14802.6 RLN83700.1 - 0.14 11.2 2.4 0.11 11.6 0.7 1.6 2 0 0 2 2 2 0 TMEM192 family HA2 PF04408.23 RLN83701.1 - 2.8e-19 69.4 0.2 9.9e-19 67.6 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RLN83701.1 - 8.1e-18 64.6 0.0 2.5e-17 63.0 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 RLN83701.1 - 3.1e-11 43.6 0.0 8.8e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RLN83701.1 - 1.3e-05 25.0 0.0 2.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RLN83701.1 - 3.8e-05 24.0 0.0 0.00011 22.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 RLN83701.1 - 0.044 12.8 0.0 0.089 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 RLN83701.1 - 0.062 13.0 0.0 0.15 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 RLN83701.1 - 0.078 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 RLN83701.1 - 0.14 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Alginate_lyase PF05426.12 RLN83702.1 - 2.2e-14 53.7 1.3 3.6e-14 53.0 1.3 1.3 1 0 0 1 1 1 1 Alginate lyase Focadhesin PF11229.8 RLN83702.1 - 0.12 10.5 0.0 0.19 9.9 0.0 1.2 1 0 0 1 1 1 0 Focadhesin Fer4_19 PF06902.11 RLN83703.1 - 0.046 13.8 0.1 0.086 12.9 0.1 1.5 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Ribosomal_S25 PF03297.15 RLN83704.1 - 9.8e-40 134.9 5.0 1.1e-39 134.7 5.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.7 RLN83704.1 - 0.0047 16.8 0.2 0.0068 16.3 0.2 1.2 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 RLN83704.1 - 0.014 15.3 0.1 0.021 14.7 0.1 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_DeoR PF08220.12 RLN83704.1 - 0.037 13.8 0.1 0.052 13.3 0.1 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain DDRGK PF09756.9 RLN83704.1 - 0.041 13.5 2.0 0.066 12.8 2.0 1.4 1 1 0 1 1 1 0 DDRGK domain MarR PF01047.22 RLN83704.1 - 0.09 12.7 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 MarR family TPR_2 PF07719.17 RLN83705.1 - 2.4e-07 30.3 3.9 0.024 14.7 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN83705.1 - 1.9e-05 24.3 1.4 1.8 8.5 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN83705.1 - 0.0013 18.8 0.1 0.084 13.1 0.0 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN83705.1 - 0.0019 18.8 7.4 0.13 13.1 0.3 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN83705.1 - 0.0042 17.7 8.3 0.31 11.7 0.2 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN83705.1 - 0.018 15.2 0.5 0.018 15.2 0.5 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 RLN83705.1 - 0.021 14.5 0.2 16 5.3 0.0 3.2 2 1 1 3 3 3 0 TPR repeat TPR_12 PF13424.6 RLN83705.1 - 0.048 14.0 9.6 0.28 11.5 1.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 RLN83705.1 - 0.12 12.8 0.1 3.9 8.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN83705.1 - 4.1 8.0 6.0 3.3 8.3 0.3 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Aldose_epim PF01263.20 RLN83706.1 - 1e-39 136.7 0.0 1.2e-39 136.4 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DTC PF18102.1 RLN83706.1 - 0.065 13.4 0.0 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 Deltex C-terminal domain TPH PF13868.6 RLN83707.1 - 4.3e-48 163.6 128.4 4.3e-48 163.6 128.4 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Alg6_Alg8 PF03155.15 RLN83708.1 - 2.1e-157 525.0 25.3 2.4e-157 524.8 25.3 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family COPIIcoated_ERV PF07970.12 RLN83709.1 - 2.5e-21 76.6 0.4 4.1e-11 43.1 0.5 2.3 1 1 1 2 2 2 2 Endoplasmic reticulum vesicle transporter Thioredoxin PF00085.20 RLN83709.1 - 0.023 14.7 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin DUF1853 PF08907.11 RLN83710.1 - 3e-22 79.6 0.1 2.9e-21 76.5 0.1 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1853) DNA_pol_A_exo1 PF01612.20 RLN83710.1 - 1.6e-12 47.5 0.0 5.4e-12 45.8 0.0 2.0 1 1 0 1 1 1 1 3'-5' exonuclease FlgT_M PF16539.5 RLN83711.1 - 0.03 14.4 0.9 0.071 13.3 0.9 1.6 1 0 0 1 1 1 0 Flagellar assembly protein T, middle domain Occludin_ELL PF07303.13 RLN83711.1 - 2.7 8.8 6.2 3.5 8.4 0.4 2.8 1 1 1 2 2 2 0 Occludin homology domain ATP-synt_ab PF00006.25 RLN83712.1 - 1.1e-105 352.0 0.0 1.8e-105 351.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 RLN83712.1 - 1.2e-39 134.9 0.0 2.2e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 RLN83712.1 - 3e-08 34.1 0.2 2.1e-07 31.4 0.2 2.5 1 1 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_18 PF13238.6 RLN83712.1 - 0.1 13.1 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Metallophos PF00149.28 RLN83713.1 - 2.8e-28 99.8 0.1 5.5e-28 98.9 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.32 RLN83713.1 - 6.8e-09 34.7 2.2 3.5e-05 23.1 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN83713.1 - 1.6e-08 33.8 1.0 0.0001 21.9 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 RLN83713.1 - 1.7e-08 34.8 0.1 4.1e-07 30.4 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN83713.1 - 8.2e-07 28.3 1.3 2.4e-05 23.6 0.1 2.5 2 0 0 2 2 2 1 EF hand PPP5 PF08321.12 RLN83713.1 - 4.8e-05 23.6 0.0 9.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 PPP5 TPR repeat region EF-hand_8 PF13833.6 RLN83713.1 - 0.00053 19.8 1.8 0.02 14.8 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain pair SprT-like PF10263.9 RLN83714.1 - 6e-07 29.3 1.3 1.3e-06 28.3 1.3 1.5 1 0 0 1 1 1 1 SprT-like family DUF4852 PF16144.5 RLN83714.1 - 0.051 13.7 0.9 1.5 8.9 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4852) PIN_6 PF17146.4 RLN83715.1 - 3.2e-28 98.1 0.0 3.2e-28 98.1 0.0 3.7 5 0 0 5 5 5 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 RLN83715.1 - 2.6e-26 91.6 0.5 5.8e-26 90.4 0.5 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-CCCH_4 PF18044.1 RLN83715.1 - 4.8e-08 32.6 13.1 0.0003 20.5 1.4 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 RLN83715.1 - 2.8e-07 30.3 10.9 0.00025 20.9 1.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 RLN83715.1 - 2.1e-06 28.0 15.9 0.00071 19.9 4.7 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 RLN83715.1 - 0.0018 18.2 13.7 0.085 12.9 2.1 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 RLN83715.1 - 0.014 15.6 4.4 1.4 9.2 0.1 2.8 1 1 1 2 2 2 0 Zinc-finger containing family DUF5620 PF18522.1 RLN83715.1 - 0.016 15.6 0.0 0.038 14.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5620) Macoilin PF09726.9 RLN83769.1 - 1.2 7.6 3.6 1.5 7.3 3.6 1.2 1 0 0 1 1 1 0 Macoilin family BP28CT PF08146.12 RLN83771.1 - 9.9e-46 155.5 0.5 3.2e-45 153.8 0.1 2.1 2 0 0 2 2 2 1 BP28CT (NUC211) domain HEAT_2 PF13646.6 RLN83771.1 - 0.00056 20.2 0.5 1.5 9.3 0.0 4.0 4 0 0 4 4 4 2 HEAT repeats Cnd1 PF12717.7 RLN83771.1 - 0.00069 19.7 2.8 2.5 8.1 0.0 3.5 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 RLN83771.1 - 0.066 13.7 5.2 12 6.5 0.1 6.2 7 2 2 9 9 9 0 HEAT-like repeat Choline_kinase PF01633.20 RLN83772.1 - 1.7e-40 138.9 0.0 4.4e-40 137.5 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 RLN83772.1 - 2.7e-10 40.6 0.1 4.6e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family zinc_ribbon_2 PF13240.6 RLN83772.1 - 0.69 9.7 3.3 0.98 9.2 0.7 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Kinesin PF00225.23 RLN83773.1 - 2.5e-86 289.7 0.9 6e-86 288.4 0.9 1.7 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN83773.1 - 6.8e-37 126.7 0.0 1.5e-36 125.6 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding CREPT PF16566.5 RLN83773.1 - 0.08 13.1 6.6 0.025 14.8 3.0 2.0 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Macoilin PF09726.9 RLN83773.1 - 0.22 10.1 11.4 0.024 13.2 5.6 2.0 2 0 0 2 2 2 0 Macoilin family DJ-1_PfpI PF01965.24 RLN83774.1 - 2.4e-16 60.0 0.0 3e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 RLN83774.1 - 0.19 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Lipocalin PF00061.23 RLN83775.1 - 0.16 12.1 0.0 0.34 11.1 0.0 1.5 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family FYVE PF01363.21 RLN83776.1 - 1.6e-15 57.0 14.6 3.4e-15 55.9 14.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger Peptidase_A22B PF04258.13 RLN83777.1 - 2e-55 188.3 4.1 1e-54 186.0 4.1 1.9 1 1 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 RLN83777.1 - 0.0028 17.6 0.1 0.0089 16.0 0.0 1.9 2 0 0 2 2 2 1 PA domain Lustrin_cystein PF14625.6 RLN83777.1 - 0.19 12.1 2.9 0.49 10.8 2.9 1.7 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain CcmH PF03918.14 RLN83777.1 - 6.3 6.1 6.3 2.5 7.4 0.0 3.3 4 0 0 4 4 4 0 Cytochrome C biogenesis protein SpoIISA_toxin PF14171.6 RLN83831.1 - 0.025 14.3 1.0 5.4 6.6 0.1 2.2 2 0 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system Tudor_2 PF18104.1 RLN83831.1 - 0.071 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain DUF3566 PF12089.8 RLN83831.1 - 0.75 10.2 7.5 0.073 13.4 1.5 2.2 1 1 1 2 2 2 0 Transmembrane domain of unknown function (DUF3566) CoA_binding_3 PF13727.6 RLN83831.1 - 3.6 7.6 6.9 0.55 10.2 0.6 2.3 2 0 0 2 2 2 0 CoA-binding domain Nucleoside_tran PF01733.18 RLN83832.1 - 8.8e-31 107.4 11.0 8.8e-31 107.4 11.0 2.3 1 1 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 RLN83832.1 - 0.00016 20.7 40.7 0.016 14.2 20.5 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5090 PF17009.5 RLN83832.1 - 5 7.0 16.2 0.36 10.8 9.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) SMC_N PF02463.19 RLN83834.1 - 4.1e-28 98.3 0.0 6.2e-28 97.7 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RLN83834.1 - 1e-13 52.2 18.4 1e-13 52.2 18.4 4.5 2 2 0 2 2 2 1 AAA domain AAA_15 PF13175.6 RLN83834.1 - 5.2e-09 36.3 0.5 5.2e-09 36.3 0.5 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 RLN83834.1 - 5.6e-06 26.4 0.1 0.00035 20.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN83834.1 - 0.0001 21.9 0.0 0.00023 20.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FlaC_arch PF05377.11 RLN83834.1 - 4.2 7.8 26.5 0.35 11.3 0.5 7.0 7 1 1 8 8 8 0 Flagella accessory protein C (FlaC) Aha1_N PF09229.11 RLN83834.1 - 6.4 7.0 10.7 0.15 12.3 0.2 3.1 2 1 0 2 2 2 0 Activator of Hsp90 ATPase, N-terminal Dimer_Tnp_hAT PF05699.14 RLN83835.1 - 2.2e-09 37.0 0.0 1.1e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Ank_2 PF12796.7 RLN83836.1 - 1.3e-41 141.0 15.0 1.1e-08 35.6 0.1 6.3 2 2 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN83836.1 - 9.7e-37 124.6 21.2 1.1e-05 25.6 0.1 13.3 6 4 7 14 14 14 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN83836.1 - 2e-33 114.3 14.5 3.5e-07 30.6 0.1 10.1 2 2 11 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN83836.1 - 1.3e-21 74.4 3.9 0.67 10.7 0.0 12.2 12 1 1 13 13 13 4 Ankyrin repeat Ank PF00023.30 RLN83836.1 - 5.3e-07 29.8 0.4 24 5.6 0.0 8.5 5 3 2 7 7 7 1 Ankyrin repeat DUF5049 PF16468.5 RLN83836.1 - 0.0011 18.8 0.0 77 3.3 0.0 5.7 6 1 1 7 7 7 0 Domain of unknown function (DUF5049) DUF4570 PF15134.6 RLN83838.1 - 0.048 13.7 1.6 0.18 11.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) DUF4615 PF15393.6 RLN83838.1 - 0.2 12.2 2.2 0.57 10.8 2.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) Rbsn PF11464.8 RLN83839.1 - 0.17 11.6 1.9 0.47 10.2 1.9 1.7 1 0 0 1 1 1 0 Rabenosyn Rab binding domain End3 PF12761.7 RLN83840.1 - 6e-05 23.3 11.9 0.00074 19.7 1.9 2.3 2 0 0 2 2 2 2 Actin cytoskeleton-regulatory complex protein END3 SAGA-Tad1 PF12767.7 RLN83840.1 - 0.01 15.6 2.3 0.01 15.6 2.3 2.2 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit Helo_like_N PF17111.5 RLN83840.1 - 0.24 10.8 3.3 0.25 10.7 0.3 2.2 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins DUF3138 PF11336.8 RLN83840.1 - 0.32 9.6 1.2 0.52 8.9 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) HSP70 PF00012.20 RLN83842.1 - 3.1e-88 296.5 0.0 3.8e-88 296.2 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Fungal_trans_2 PF11951.8 RLN83843.1 - 0.1 11.4 0.9 1 8.1 0.9 2.0 1 1 0 1 1 1 0 Fungal specific transcription factor domain HTH_Tnp_Tc5 PF03221.16 RLN83844.1 - 0.0013 18.8 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_32 PF13565.6 RLN83844.1 - 0.12 13.0 0.0 0.25 12.0 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain ABC_membrane PF00664.23 RLN83910.1 - 4e-63 213.6 1.8 8.2e-37 127.3 0.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN83910.1 - 1.2e-53 181.3 0.0 1e-26 94.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_22 PF13401.6 RLN83910.1 - 9.8e-06 25.9 0.2 0.051 13.8 0.0 3.7 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 RLN83910.1 - 3.3e-05 23.6 0.0 0.026 14.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN83910.1 - 0.00085 19.3 0.0 0.062 13.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 RLN83910.1 - 0.0052 17.3 0.0 2.2 8.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 RLN83910.1 - 0.0053 16.4 1.5 4 7.0 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.6 RLN83910.1 - 0.02 15.0 2.4 1.7 8.8 0.0 3.8 3 1 0 3 3 3 0 AAA domain Ploopntkinase3 PF18751.1 RLN83910.1 - 0.021 14.7 0.1 36 4.2 0.0 3.6 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 IstB_IS21 PF01695.17 RLN83910.1 - 0.022 14.5 0.4 3.3 7.4 0.0 3.6 3 0 0 3 3 3 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 RLN83910.1 - 0.046 13.8 0.0 6.4 6.9 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_21 PF13304.6 RLN83910.1 - 0.05 13.4 0.0 1.3 8.8 0.0 2.5 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system APS_kinase PF01583.20 RLN83910.1 - 0.052 13.5 0.1 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_16 PF13191.6 RLN83910.1 - 0.14 12.5 15.7 0.56 10.6 0.2 4.9 6 1 0 6 6 5 0 AAA ATPase domain PRK PF00485.18 RLN83910.1 - 0.18 11.5 0.1 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_15 PF13175.6 RLN83910.1 - 0.37 10.5 0.0 0.6 9.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain PHO4 PF01384.20 RLN83911.1 - 1.7e-15 56.9 9.2 1.9e-15 56.8 9.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family Arf PF00025.21 RLN83914.1 - 3.4e-57 192.7 0.1 6.6e-57 191.8 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RLN83914.1 - 2.2e-13 50.5 0.3 4.2e-13 49.6 0.3 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RLN83914.1 - 3.3e-11 43.0 0.2 6.1e-11 42.2 0.2 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 RLN83914.1 - 9.9e-09 34.9 1.7 2.2e-08 33.8 0.1 2.2 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RLN83914.1 - 5.4e-07 29.1 1.0 0.00011 21.5 0.3 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 RLN83914.1 - 2.6e-06 27.5 0.0 5.7e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Lzipper-MIP1 PF14389.6 RLN83914.1 - 0.033 14.5 2.1 0.4 11.0 0.5 2.7 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 AAA_14 PF13173.6 RLN83914.1 - 0.13 12.3 0.1 0.42 10.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 RLN83915.1 - 2.2e-64 216.8 65.1 2.3e-37 128.5 20.3 2.8 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN83915.1 - 6.5e-33 114.2 0.0 5.2e-16 59.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 RLN83915.1 - 4.4e-07 30.0 0.1 0.00095 19.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase ABC2_membrane_3 PF12698.7 RLN83915.1 - 7e-07 28.7 14.5 7e-07 28.7 14.5 2.7 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 RLN83915.1 - 1.3e-06 28.0 0.9 0.0065 16.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN83915.1 - 2.7e-05 24.5 0.0 0.32 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 RLN83915.1 - 9.5e-05 22.1 0.4 0.42 10.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 RLN83915.1 - 0.00027 21.0 0.0 1 9.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 RLN83915.1 - 0.00029 20.7 1.3 2.8 7.7 0.0 3.5 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 RLN83915.1 - 0.00035 21.1 0.0 1.5 9.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RLN83915.1 - 0.00056 20.5 1.1 0.6 10.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 RLN83915.1 - 0.00098 19.3 0.0 0.55 10.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN83915.1 - 0.0017 18.8 0.0 1.6 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 RLN83915.1 - 0.003 17.3 3.1 1.3 8.7 0.3 2.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 RLN83915.1 - 0.0031 17.9 0.5 3.3 8.1 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PDR_assoc PF08370.11 RLN83915.1 - 0.0034 17.1 1.0 0.0034 17.1 1.0 2.7 2 0 0 2 2 2 1 Plant PDR ABC transporter associated AAA_28 PF13521.6 RLN83915.1 - 0.017 15.4 0.4 0.72 10.1 0.2 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 RLN83915.1 - 0.036 14.1 1.3 1.8 8.6 0.2 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 RLN83915.1 - 0.051 14.0 0.0 13 6.2 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 RLN83915.1 - 0.062 13.0 2.4 2.1 8.0 0.2 2.4 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 RLN83915.1 - 0.078 12.0 0.3 8.1 5.3 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 RLN83915.1 - 0.085 12.1 2.3 6.2 6.0 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 RLN83915.1 - 0.1 12.5 2.3 4.4 7.2 0.4 2.4 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 RLN83915.1 - 0.27 11.1 1.8 7 6.5 0.0 2.6 3 0 0 3 3 2 0 NTPase cobW PF02492.19 RLN83915.1 - 0.28 10.8 2.5 7.3 6.1 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 RLN83915.1 - 0.77 10.1 2.5 6.1 7.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain IF-2B PF01008.17 RLN83916.1 - 3e-71 239.9 0.0 3.8e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family HSBP1 PF06825.12 RLN83917.1 - 0.051 13.4 2.0 3.9 7.4 0.3 2.9 2 1 1 3 3 3 0 Heat shock factor binding protein 1 DUF1779 PF08680.10 RLN83917.1 - 1.3 9.1 6.4 2.6 8.2 1.3 2.2 2 0 0 2 2 2 0 TATA-box binding Jnk-SapK_ap_N PF09744.9 RLN83917.1 - 8.4 6.6 11.4 0.11 12.8 1.8 2.4 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 AAA_lid_3 PF17862.1 RLN83918.1 - 0.00064 19.5 0.4 0.0039 17.0 0.4 2.0 2 0 0 2 2 2 1 AAA+ lid domain HTH_11 PF08279.12 RLN83918.1 - 0.05 13.5 0.1 0.72 9.8 0.0 2.0 2 0 0 2 2 2 0 HTH domain HTH_10 PF04967.12 RLN83918.1 - 0.092 12.6 0.4 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 HTH DNA binding domain eIF-1a PF01176.19 RLN83920.1 - 9.7e-22 76.6 0.2 1.4e-21 76.1 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Proteasome PF00227.26 RLN83921.1 - 9.4e-47 159.0 0.0 1.1e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit TPR_12 PF13424.6 RLN83922.1 - 6.2e-15 55.2 13.8 1.7e-05 25.0 1.5 4.6 2 1 1 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 RLN83922.1 - 2e-12 46.4 8.3 0.0019 17.9 0.2 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN83922.1 - 9.6e-12 44.1 6.4 0.0066 16.5 0.4 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 RLN83922.1 - 1.1e-11 44.2 8.5 3.7e-05 23.4 2.6 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN83922.1 - 5.8e-10 38.6 7.8 0.00036 20.5 0.2 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN83922.1 - 5e-05 23.0 6.5 0.005 16.8 0.8 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN83922.1 - 0.022 15.4 0.7 0.19 12.4 0.7 2.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN83922.1 - 0.05 14.4 3.6 7.9 7.6 0.2 4.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 RLN83922.1 - 0.05 13.3 1.8 0.61 9.8 0.0 3.2 3 0 0 3 3 3 0 TPR repeat OGFr_N PF04664.13 RLN83922.1 - 0.11 12.1 0.2 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Opioid growth factor receptor (OGFr) conserved region FAT PF02259.23 RLN83922.1 - 1.2 8.2 5.2 0.26 10.5 0.3 2.1 2 1 0 2 2 2 0 FAT domain ANAPC3 PF12895.7 RLN83922.1 - 3.9 7.8 6.1 12 6.2 3.7 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Retrotran_gag_2 PF14223.6 RLN83973.1 - 6.1e-10 38.9 0.0 8.8e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_3 PF13917.6 RLN83973.1 - 0.0028 17.6 3.7 0.0063 16.5 3.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 RLN83973.1 - 0.0029 17.6 3.4 0.0068 16.4 3.4 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 RLN83973.1 - 0.19 11.6 2.2 0.37 10.7 2.2 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF3638 PF12340.8 RLN83975.1 - 1.9e-59 200.8 0.2 3.5e-59 199.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 RLN83975.1 - 8.2e-16 57.1 3.9 4.9e-15 54.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3645) SKG6 PF08693.10 RLN83976.1 - 0.0012 18.2 1.3 0.0024 17.2 1.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain PTP_tm PF18861.1 RLN83976.1 - 0.004 17.2 0.0 0.0084 16.1 0.0 1.5 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J MtrF PF09472.10 RLN83976.1 - 0.0085 15.5 2.0 0.016 14.6 2.0 1.4 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Mid2 PF04478.12 RLN83976.1 - 0.023 14.5 0.0 0.023 14.5 0.0 2.3 3 0 0 3 3 3 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.6 RLN83976.1 - 0.088 13.7 0.0 0.2 12.5 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SIT PF15330.6 RLN83976.1 - 0.13 12.7 0.0 2.4 8.7 0.0 2.6 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT TMEM154 PF15102.6 RLN83976.1 - 0.55 10.1 0.0 0.55 10.1 0.0 3.5 3 1 0 3 3 3 0 TMEM154 protein family MFS_1 PF07690.16 RLN83977.1 - 5.2e-20 71.7 32.1 1.1e-13 50.9 13.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 RLN83977.1 - 1.1e-05 25.1 6.3 1.1e-05 25.1 6.3 2.4 2 1 0 2 2 2 1 Nodulin-like Bact_lectin PF18483.1 RLN83977.1 - 0.19 11.8 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial lectin MFS_1 PF07690.16 RLN83978.1 - 3.7e-20 72.1 34.3 3.7e-20 72.1 34.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 RLN83978.1 - 1.4e-05 24.8 8.1 1.4e-05 24.8 8.1 1.8 2 0 0 2 2 2 1 Nodulin-like DUF2892 PF11127.8 RLN83978.1 - 0.019 15.0 0.5 0.019 15.0 0.5 5.4 5 0 0 5 5 5 0 Protein of unknown function (DUF2892) Podoplanin PF05808.11 RLN83979.1 - 0.0041 17.2 1.4 0.0041 17.2 1.4 2.3 2 1 0 2 2 2 1 Podoplanin CxxCxxCC PF03692.15 RLN83980.1 - 0.00078 20.1 0.0 0.0078 16.9 0.0 2.3 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain WD40 PF00400.32 RLN83981.1 - 0.15 13.0 0.1 1.1 10.2 0.0 2.6 3 0 0 3 3 3 0 WD domain, G-beta repeat Sororin PF09666.10 RLN83982.1 - 0.02 15.1 0.2 0.11 12.7 0.1 2.0 2 0 0 2 2 2 0 Sororin protein DUF3742 PF12553.8 RLN83982.1 - 0.022 14.9 0.1 0.037 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) FAM176 PF14851.6 RLN83982.1 - 0.059 13.0 0.3 0.85 9.3 0.0 2.2 2 0 0 2 2 2 0 FAM176 family TMEM51 PF15345.6 RLN83982.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 Herpes_gE PF02480.16 RLN83982.1 - 0.072 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.6 RLN83982.1 - 0.079 12.9 0.2 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family PBP_N PF17093.5 RLN83982.1 - 0.081 13.2 0.4 0.53 10.5 0.0 2.2 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus BatD PF13584.6 RLN83982.1 - 0.16 10.7 0.0 0.16 10.7 0.0 2.0 2 0 0 2 2 2 0 Oxygen tolerance EphA2_TM PF14575.6 RLN83982.1 - 0.18 12.7 0.0 0.4 11.6 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2840 PF11000.8 RLN83983.1 - 0.073 12.9 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2840) BT1 PF03092.16 RLN83984.1 - 5.4e-08 31.5 0.7 1.4e-05 23.6 0.2 2.3 2 0 0 2 2 2 2 BT1 family MAGE_N PF12440.8 RLN83985.1 - 4.9 7.9 7.6 2.6 8.8 0.9 2.3 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal ACT_7 PF13840.6 RLN83987.1 - 6e-21 74.0 0.1 2.5e-12 46.4 0.1 2.3 2 0 0 2 2 2 2 ACT domain Castor1_N PF18700.1 RLN83987.1 - 0.026 14.3 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain Nuc_sug_transp PF04142.15 RLN83988.1 - 2.1e-80 270.3 18.8 2.4e-80 270.1 18.8 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 RLN83988.1 - 1.8e-06 27.4 17.4 3.3e-06 26.5 17.4 1.5 1 1 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 RLN83988.1 - 5.6e-05 22.2 0.8 5.6e-05 22.2 0.8 2.2 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 RLN83988.1 - 0.0084 15.5 2.9 0.0084 15.5 2.9 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.20 RLN83988.1 - 0.19 11.9 25.9 0.027 14.6 4.7 3.6 2 2 0 3 3 3 0 EamA-like transporter family DUF4077 PF13295.6 RLN83988.1 - 5.7 6.8 13.0 0.15 12.0 5.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4077) Metallophos_2 PF12850.7 RLN83989.1 - 1.9e-07 31.4 0.1 0.0052 17.0 0.1 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain ABC_tran_CTD PF16326.5 RLN83990.1 - 0.0061 16.8 2.8 0.0061 16.8 2.8 3.4 2 1 1 3 3 3 2 ABC transporter C-terminal domain CENP-H PF05837.12 RLN83990.1 - 0.069 13.6 30.6 0.098 13.1 11.8 2.8 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Campylo_MOMP PF05538.11 RLN83990.1 - 0.079 11.9 1.0 0.093 11.7 1.0 1.2 1 0 0 1 1 1 0 Campylobacter major outer membrane protein FlaC_arch PF05377.11 RLN83990.1 - 0.24 11.8 7.0 0.81 10.1 0.6 3.4 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Acyl-thio_N PF12590.8 RLN83990.1 - 0.66 10.5 7.4 0.18 12.4 0.5 2.2 2 1 0 2 2 2 0 Acyl-ATP thioesterase DUF1664 PF07889.12 RLN83990.1 - 1 9.4 13.2 2.1 8.4 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Allexi_40kDa PF05549.11 RLN83990.1 - 1.2 8.5 12.7 0.7 9.4 4.8 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein YkyA PF10368.9 RLN83990.1 - 1.3 8.7 27.4 0.016 14.9 14.1 2.4 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein Alpha_Helical PF18489.1 RLN83990.1 - 3.9 7.7 10.4 0.41 10.8 2.8 2.3 1 1 1 2 2 2 0 Alpha helical domain Pex24p PF06398.11 RLN83991.1 - 1.1e-05 24.6 0.0 1.1e-05 24.6 0.0 2.1 3 0 0 3 3 3 1 Integral peroxisomal membrane peroxin HALZ PF02183.18 RLN83991.1 - 0.033 14.4 0.4 0.033 14.4 0.4 2.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper PUB PF09409.10 RLN83991.1 - 0.089 12.7 0.0 0.27 11.2 0.0 1.8 1 0 0 1 1 1 0 PUB domain DUF4355 PF14265.6 RLN83991.1 - 0.43 10.8 9.0 0.75 10.0 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DivIC PF04977.15 RLN83991.1 - 7.5 6.4 10.1 1.4 8.7 3.3 2.4 1 1 1 2 2 2 0 Septum formation initiator Abhydrolase_6 PF12697.7 RLN83993.1 - 8.8e-16 59.2 3.6 1.2e-15 58.7 3.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN83993.1 - 1.1e-06 28.5 0.0 1.8e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN83993.1 - 4.4e-06 26.1 1.2 1.4e-05 24.5 1.2 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 RLN83993.1 - 0.0037 17.0 0.0 0.0072 16.1 0.0 1.5 2 0 0 2 2 2 1 PGAP1-like protein Lipase_3 PF01764.25 RLN83993.1 - 0.0037 17.1 0.0 0.0073 16.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.7 RLN83993.1 - 0.017 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 RLN83993.1 - 0.021 13.7 0.0 0.028 13.3 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme Ser_hydrolase PF06821.13 RLN83993.1 - 0.039 13.8 0.1 0.063 13.1 0.1 1.3 1 0 0 1 1 1 0 Serine hydrolase Esterase PF00756.20 RLN83993.1 - 0.05 13.2 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 RLN83993.1 - 0.16 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain SNF2_N PF00176.23 RLN84045.1 - 1.6e-63 214.6 0.0 2.6e-63 213.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN84045.1 - 4.8e-10 39.8 0.0 1.1e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 RLN84045.1 - 6e-06 26.0 10.1 1.2e-05 25.0 10.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN84045.1 - 0.00063 19.6 8.2 0.00063 19.6 8.2 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN84045.1 - 0.00072 19.5 9.9 0.0017 18.3 9.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain F-box-like PF12937.7 RLN84045.1 - 0.006 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RLN84045.1 - 0.025 14.5 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 F-box domain DUF2726 PF10881.8 RLN84045.1 - 0.039 13.8 0.3 0.14 12.0 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) zf-C3HC4 PF00097.25 RLN84045.1 - 0.043 13.7 10.3 0.085 12.7 10.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) F-box_4 PF15966.5 RLN84045.1 - 0.044 13.7 0.1 0.095 12.6 0.1 1.5 1 0 0 1 1 1 0 F-box ERCC3_RAD25_C PF16203.5 RLN84045.1 - 0.046 12.9 0.0 0.09 12.0 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 RLN84045.1 - 0.16 11.9 0.0 7.5 6.5 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 RLN84045.1 - 0.18 11.7 11.6 0.43 10.5 11.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) LRS4 PF10422.9 RLN84045.1 - 0.27 10.8 2.6 0.94 9.0 0.1 2.3 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 NPCBM_assoc PF10633.9 RLN84045.1 - 0.34 11.2 2.1 1.1 9.6 2.1 1.8 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase zf-C3HC4_4 PF15227.6 RLN84045.1 - 0.75 10.0 9.5 1.8 8.8 9.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 RLN84045.1 - 2.4 8.3 9.6 4.9 7.3 9.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 RLN84045.1 - 4.3 7.8 14.3 1.3 9.4 10.8 2.0 2 0 0 2 2 2 0 Ring finger domain HMA PF00403.26 RLN84046.1 - 1.9e-11 44.2 0.7 2.3e-11 44.0 0.7 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Peptidase_Prp PF04327.12 RLN84046.1 - 0.096 12.9 0.2 0.11 12.8 0.2 1.1 1 0 0 1 1 1 0 Cysteine protease Prp Sld5 PF05916.11 RLN84047.1 - 2.3e-09 37.7 0.0 3.6e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Asp_Arg_Hydrox PF05118.15 RLN84048.1 - 2.8e-46 157.2 0.1 4e-46 156.7 0.1 1.2 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Cupin_2 PF07883.11 RLN84048.1 - 0.024 14.4 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Cupin domain AraC_binding PF02311.19 RLN84048.1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 AraC-like ligand binding domain AAA_6 PF12774.7 RLN84049.1 - 2.4e-154 513.2 0.0 1.5e-152 507.3 0.0 2.9 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN84049.1 - 9.1e-133 443.2 8.3 9.1e-133 443.2 8.3 2.4 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RLN84049.1 - 1.3e-97 326.2 0.0 4.8e-97 324.3 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RLN84049.1 - 1.7e-83 279.1 0.1 1.1e-82 276.4 0.0 2.6 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 RLN84049.1 - 3.8e-81 270.9 0.0 2.7e-77 258.4 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region Dynein_C PF18199.1 RLN84049.1 - 1.4e-65 221.5 0.4 7.3e-65 219.2 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 RLN84049.1 - 8.2e-53 178.6 0.1 1.8e-52 177.5 0.1 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RLN84049.1 - 4.3e-46 155.9 0.0 2.8e-42 143.6 0.0 3.1 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 RLN84049.1 - 9.4e-45 153.1 12.6 1.5e-44 152.4 12.6 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 RLN84049.1 - 6.5e-33 113.6 0.0 2.2e-32 111.9 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RLN84049.1 - 1.4e-22 79.7 0.2 1e-21 77.0 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 RLN84049.1 - 1.7e-19 70.2 0.0 1.6e-05 24.9 0.0 5.5 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RLN84049.1 - 0.0001 22.6 0.1 6.7 7.0 0.0 4.4 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 RLN84049.1 - 0.0024 17.0 0.2 0.13 11.3 0.0 3.1 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_18 PF13238.6 RLN84049.1 - 0.0027 18.2 0.0 0.13 12.8 0.0 3.5 2 0 0 2 2 2 1 AAA domain DUF853 PF05872.12 RLN84049.1 - 0.0041 15.8 9.5 0.56 8.7 0.1 3.9 4 0 0 4 4 4 2 Bacterial protein of unknown function (DUF853) AAA PF00004.29 RLN84049.1 - 0.0048 17.3 0.1 0.94 9.9 0.1 3.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 RLN84049.1 - 0.011 15.2 1.3 1 8.7 0.0 3.7 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 RLN84049.1 - 0.013 15.9 7.5 6.8 7.0 0.0 5.7 5 0 0 5 5 5 0 AAA ATPase domain DUF87 PF01935.17 RLN84049.1 - 0.028 14.5 0.5 2.1 8.4 0.1 3.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 RLN84049.1 - 0.032 14.0 5.5 6.3 6.5 0.2 3.9 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 RLN84049.1 - 0.051 14.0 0.1 4.4 7.8 0.0 3.1 3 0 0 3 3 3 0 RNA helicase SRP54 PF00448.22 RLN84049.1 - 0.1 12.2 3.7 32 4.1 0.0 3.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.18 RLN84049.1 - 0.12 11.7 0.3 5.6 6.2 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.6 RLN84049.1 - 0.16 12.3 4.0 2.4 8.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain T4SS-DNA_transf PF02534.14 RLN84049.1 - 0.22 10.3 1.4 3.5 6.3 0.5 2.2 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer TrwB_AAD_bind PF10412.9 RLN84049.1 - 0.28 10.0 4.3 1.4 7.8 0.1 3.5 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.6 RLN84049.1 - 0.98 9.6 3.1 28 4.9 0.0 3.7 4 0 0 4 4 2 0 AAA domain Laminin_II PF06009.12 RLN84049.1 - 1.2 9.2 14.4 4.5 7.3 4.1 3.2 2 1 0 2 2 2 0 Laminin Domain II Sec34 PF04136.15 RLN84049.1 - 5.5 6.9 7.8 19 5.1 2.8 3.6 3 0 0 3 3 3 0 Sec34-like family Spc7 PF08317.11 RLN84049.1 - 7.6 5.3 22.2 1.2 8.0 2.9 3.3 3 0 0 3 3 3 0 Spc7 kinetochore protein VWA_2 PF13519.6 RLN84050.1 - 4e-12 46.7 0.3 4.9e-11 43.2 0.0 2.8 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 RLN84050.1 - 0.0002 21.7 0.0 0.00057 20.2 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain INT_SG_DDX_CT_C PF15300.6 RLN84050.1 - 0.011 15.5 1.8 0.47 10.3 0.1 2.9 3 0 0 3 3 3 0 INTS6/SAGE1/DDX26B/CT45 C-terminus MPS-4 PF17523.2 RLN84051.1 - 0.076 13.2 2.6 10 6.3 0.1 3.7 2 0 0 2 2 2 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 DUF3697 PF12478.8 RLN84051.1 - 0.13 12.4 0.2 0.35 11.0 0.2 1.7 1 0 0 1 1 1 0 Ubiquitin-associated protein 2 Sdh_cyt PF01127.22 RLN84053.1 - 6.9e-05 22.9 0.3 9.8e-05 22.4 0.3 1.3 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit zf-C2H2 PF00096.26 RLN84054.1 - 1.7e-24 84.9 22.8 4.4e-06 26.9 0.4 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN84054.1 - 5.7e-17 61.0 19.5 0.0012 19.5 0.8 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RLN84054.1 - 6.4e-17 61.1 22.4 6.8e-06 26.3 0.1 5.3 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2_6 PF13912.6 RLN84054.1 - 3.4e-08 33.3 12.6 0.019 15.0 0.2 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RLN84054.1 - 2.5e-06 27.6 6.8 0.16 12.3 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 RLN84054.1 - 5.1e-05 22.9 17.1 0.097 12.4 0.1 4.8 4 1 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 RLN84054.1 - 0.00012 21.7 17.1 0.041 13.6 0.6 4.2 4 0 0 4 4 4 3 zinc-finger C2H2-type zf_ZIC PF18366.1 RLN84054.1 - 0.00022 21.2 3.6 1.4 9.1 0.2 4.2 3 1 1 4 4 4 1 Zic proteins zinc finger domain zf-TRAF PF02176.18 RLN84054.1 - 0.00025 21.7 5.2 0.083 13.6 0.2 2.4 2 0 0 2 2 2 2 TRAF-type zinc finger FOXP-CC PF16159.5 RLN84054.1 - 0.00075 20.1 3.4 0.25 12.0 0.1 3.4 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 RLN84054.1 - 0.0049 17.1 8.9 0.048 14.0 5.4 2.5 1 1 2 3 3 3 2 C2H2-type zinc ribbon zf-met PF12874.7 RLN84054.1 - 0.04 14.3 10.0 0.47 10.9 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RLN84054.1 - 0.045 14.1 8.6 21 5.5 0.1 3.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 RLN84054.1 - 0.073 13.4 8.3 0.5 10.7 1.4 3.1 1 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_aberr PF17017.5 RLN84054.1 - 0.13 12.3 4.8 16 5.6 0.3 3.2 1 1 1 3 3 3 0 Aberrant zinc-finger DUF4729 PF15866.5 RLN84054.1 - 0.61 9.4 6.7 0.49 9.7 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4729) Zn_ribbon_SprT PF17283.2 RLN84054.1 - 2 8.4 6.4 1.3 9.0 3.0 2.4 1 1 1 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2 PF00096.26 RLN84055.1 - 2e-15 56.3 24.3 0.00014 22.1 1.5 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN84055.1 - 7.9e-15 54.3 21.0 0.00044 20.9 0.9 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RLN84055.1 - 4.5e-12 45.8 24.7 0.0014 18.9 1.3 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RLN84055.1 - 1.3e-06 28.5 0.8 0.31 11.4 0.0 4.3 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 RLN84055.1 - 9.9e-05 22.0 13.4 0.074 12.8 0.7 4.5 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-met PF12874.7 RLN84055.1 - 0.00087 19.6 3.5 1.1 9.8 0.1 4.5 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 RLN84055.1 - 0.0017 18.6 7.6 0.16 12.2 1.4 3.1 1 1 2 3 3 3 3 C2H2-type zinc ribbon zf-Di19 PF05605.12 RLN84055.1 - 0.0048 17.2 10.2 0.018 15.3 0.7 3.3 2 1 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 RLN84055.1 - 0.013 15.4 13.7 0.93 9.6 0.3 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 RLN84055.1 - 0.031 14.9 5.6 3 8.5 0.1 2.9 3 0 0 3 3 3 0 FOXP coiled-coil domain zf_ZIC PF18366.1 RLN84055.1 - 0.087 12.9 3.9 14 5.9 0.1 3.4 2 1 1 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_9 PF16293.5 RLN84055.1 - 0.14 12.0 5.6 15 5.6 0.1 4.0 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_aberr PF17017.5 RLN84055.1 - 0.38 10.9 4.8 14 5.8 0.5 3.1 1 1 3 4 4 4 0 Aberrant zinc-finger zf-C2HC_2 PF13913.6 RLN84055.1 - 0.51 10.3 6.0 21 5.2 0.9 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 RLN84055.1 - 0.64 9.8 14.2 4.7 7.1 0.1 4.9 4 1 0 4 4 4 0 C2H2-type zinc-finger domain CHORD PF04968.12 RLN84055.1 - 2.5 8.9 8.7 4.7 8.0 0.5 3.4 2 2 2 4 4 4 0 CHORD Pkinase_Tyr PF07714.17 RLN84057.1 - 2.3e-42 145.1 0.0 4.9e-42 144.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RLN84057.1 - 1.2e-36 126.4 0.0 2.4e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.23 RLN84057.1 - 9e-12 44.6 0.2 0.017 15.2 0.0 4.4 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat ABC1 PF03109.16 RLN84057.1 - 0.00091 19.4 0.0 0.0026 17.9 0.0 1.7 1 0 0 1 1 1 1 ABC1 family HEAT_EZ PF13513.6 RLN84057.1 - 0.0025 18.3 1.1 0.085 13.4 0.0 3.7 3 0 0 3 3 3 1 HEAT-like repeat DZR PF12773.7 RLN84057.1 - 0.0028 17.7 0.4 0.0064 16.5 0.4 1.5 1 0 0 1 1 1 1 Double zinc ribbon Prok-E2_C PF14459.6 RLN84057.1 - 0.0067 16.6 0.2 1.1 9.4 0.0 3.4 1 1 2 3 3 3 1 Prokaryotic E2 family C zinc_ribbon_15 PF17032.5 RLN84057.1 - 0.015 16.0 0.2 0.034 14.9 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon family zinc_ribbon_2 PF13240.6 RLN84057.1 - 0.045 13.5 0.5 0.1 12.3 0.5 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Atx10homo_assoc PF09759.9 RLN84057.1 - 0.069 13.2 0.0 0.65 10.0 0.0 2.6 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain DUF123 PF01986.16 RLN84057.1 - 0.098 13.2 0.1 1.3 9.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF123 NOB1_Zn_bind PF08772.11 RLN84057.1 - 0.18 12.0 0.4 0.37 11.0 0.4 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like RyR PF02026.16 RLN84058.1 - 1.1e-43 147.3 0.0 2e-22 79.2 0.0 2.4 2 0 0 2 2 2 2 RyR domain Pkinase PF00069.25 RLN84058.1 - 3.2e-39 134.9 0.0 5.5e-38 130.8 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN84058.1 - 7.4e-19 68.0 0.0 1.7e-08 34.1 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase PH PF00169.29 RLN84058.1 - 2.7e-06 27.8 0.0 7.4e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 PH domain APH PF01636.23 RLN84058.1 - 0.0071 16.3 0.2 0.53 10.2 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family S1-P1_nuclease PF02265.16 RLN84059.1 - 1.2e-35 123.6 0.0 1.6e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 S1/P1 Nuclease DUF948 PF06103.11 RLN84060.1 - 0.0016 18.6 6.9 1.3 9.3 0.1 3.8 4 0 0 4 4 4 2 Bacterial protein of unknown function (DUF948) zf-C4H2 PF10146.9 RLN84060.1 - 0.0041 17.4 1.8 0.0041 17.4 1.8 3.0 1 1 2 3 3 3 1 Zinc finger-containing protein TMF_DNA_bd PF12329.8 RLN84060.1 - 0.5 10.4 23.2 1 9.4 2.6 5.0 4 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding FAM76 PF16046.5 RLN84060.1 - 0.62 9.4 16.6 0.049 13.0 9.4 2.2 1 1 1 2 2 2 0 FAM76 protein PTPlike_phytase PF14566.6 RLN84060.1 - 1.3 9.1 7.6 0.12 12.5 1.7 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate PI3K_P85_iSH2 PF16454.5 RLN84060.1 - 4.1 7.0 31.7 0.65 9.6 10.7 3.8 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Tweety PF04906.13 RLN84060.1 - 4.5 5.8 5.1 14 4.2 0.1 2.3 2 0 0 2 2 2 0 Tweety MCC-bdg_PDZ PF10506.9 RLN84060.1 - 7.6 6.6 12.8 0.4 10.7 1.5 3.8 2 2 2 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Seryl_tRNA_N PF02403.22 RLN84060.1 - 8.9 6.6 25.5 9.5 6.5 1.7 4.2 3 2 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Myosin_tail_1 PF01576.19 RLN84061.1 - 0.0014 16.5 24.1 0.0019 16.1 24.1 1.1 1 0 0 1 1 1 1 Myosin tail DUF4200 PF13863.6 RLN84061.1 - 0.0029 18.0 14.2 0.0029 18.0 14.2 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) FPP PF05911.11 RLN84061.1 - 0.012 13.9 20.4 0.015 13.5 20.4 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Ax_dynein_light PF10211.9 RLN84061.1 - 0.02 14.9 21.4 0.043 13.8 9.8 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain Filament PF00038.21 RLN84061.1 - 0.053 13.1 23.0 0.057 13.0 11.5 2.1 1 1 1 2 2 2 0 Intermediate filament protein TMCO5 PF14992.6 RLN84061.1 - 0.065 12.8 17.4 0.1 12.2 17.4 1.3 1 0 0 1 1 1 0 TMCO5 family Spc7 PF08317.11 RLN84061.1 - 0.075 11.9 23.5 0.045 12.6 16.8 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Cortex-I_coil PF09304.10 RLN84061.1 - 0.09 13.0 20.1 0.024 14.9 9.6 2.5 1 1 1 2 2 2 0 Cortexillin I, coiled coil Jnk-SapK_ap_N PF09744.9 RLN84061.1 - 0.14 12.4 28.8 0.9 9.7 11.7 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 ATG16 PF08614.11 RLN84061.1 - 0.16 12.2 29.1 0.083 13.1 14.1 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 RLN84061.1 - 0.23 11.5 25.7 0.18 11.8 22.1 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4172 PF13776.6 RLN84061.1 - 0.33 11.3 6.4 0.47 10.8 1.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4172) DUF1359 PF07097.11 RLN84061.1 - 0.35 11.1 2.9 0.59 10.4 2.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1359) TPR_MLP1_2 PF07926.12 RLN84061.1 - 0.64 10.1 31.0 1.1 9.3 14.8 2.8 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.7 RLN84061.1 - 0.67 10.1 25.5 2.7 8.1 7.6 2.5 1 1 0 2 2 2 0 Tropomyosin like DUF3027 PF11228.8 RLN84061.1 - 0.87 9.6 3.9 1.3 9.0 3.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3027) Flagellin_C PF00700.21 RLN84061.1 - 0.97 9.8 11.5 0.29 11.5 4.0 2.4 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region MPS2 PF17060.5 RLN84061.1 - 1.1 8.5 16.9 0.45 9.7 3.8 2.1 1 1 1 2 2 2 0 Monopolar spindle protein 2 JIP_LZII PF16471.5 RLN84061.1 - 1.4 9.1 15.6 0.13 12.5 1.3 3.7 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II HAUS-augmin3 PF14932.6 RLN84061.1 - 1.4 8.4 25.8 0.73 9.4 12.1 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 KASH_CCD PF14662.6 RLN84061.1 - 1.5 8.6 25.9 3.1 7.6 13.0 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH HALZ PF02183.18 RLN84061.1 - 1.7 8.9 10.5 5.4 7.3 0.7 3.7 3 1 1 4 4 4 0 Homeobox associated leucine zipper FliJ PF02050.16 RLN84061.1 - 1.7 8.8 26.4 0.036 14.3 11.7 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein DUF724 PF05266.14 RLN84061.1 - 2.1 8.1 20.2 1.9 8.3 8.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 RLN84061.1 - 3.2 7.8 13.2 0.36 10.9 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 RLN84061.1 - 3.6 7.6 28.0 0.094 12.7 8.5 3.4 2 1 2 4 4 3 0 TATA element modulatory factor 1 DNA binding DUF1515 PF07439.11 RLN84061.1 - 5.4 7.1 6.8 13 5.9 5.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) ADIP PF11559.8 RLN84061.1 - 5.5 7.1 31.1 3.1 7.9 14.5 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CLZ PF16526.5 RLN84061.1 - 5.8 7.3 19.9 4.4 7.7 7.3 2.8 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3552 PF12072.8 RLN84061.1 - 6 6.2 27.6 0.053 12.9 12.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Fez1 PF06818.15 RLN84061.1 - 6.7 7.1 25.8 6.9 7.1 9.2 2.1 1 1 1 2 2 2 0 Fez1 GIT_CC PF16559.5 RLN84061.1 - 7.1 6.6 20.1 5.4 7.0 3.3 3.7 1 1 3 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor zf-C4pol PF14260.6 RLN84061.1 - 8.1 7.0 14.4 3.5 8.1 2.6 3.1 2 1 1 3 3 2 0 C4-type zinc-finger of DNA polymerase delta CorA PF01544.18 RLN84061.1 - 9 5.5 9.9 4.3 6.6 6.8 1.7 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein PAS_4 PF08448.10 RLN84064.1 - 0.095 13.0 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 PAS fold DUF5305 PF17231.2 RLN84065.1 - 0.049 13.0 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) CD34_antigen PF06365.12 RLN84065.1 - 0.11 12.1 0.2 0.22 11.1 0.2 1.5 1 1 1 2 2 2 0 CD34/Podocalyxin family Thioredoxin PF00085.20 RLN84066.1 - 7.3e-06 25.9 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin ATP-synt_E PF05680.12 RLN84066.1 - 5.4 7.4 8.7 25 5.3 4.9 2.4 2 0 0 2 2 2 0 ATP synthase E chain PA_decarbox PF05870.11 RLN84067.1 - 4.1e-09 36.2 0.1 4.9e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) MoaF PF10703.9 RLN84067.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 MoaF N-terminal domain Ank_2 PF12796.7 RLN84068.1 - 4.6e-26 91.2 3.2 9.2e-08 32.6 0.1 5.6 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN84068.1 - 4.8e-22 78.0 0.9 0.051 14.2 0.0 6.7 5 1 1 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 RLN84068.1 - 3e-19 68.5 11.3 0.02 15.4 0.0 8.8 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 RLN84068.1 - 4.9e-17 61.8 6.3 0.002 18.4 0.1 6.7 3 1 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN84068.1 - 4.3e-16 57.4 4.9 0.28 11.9 0.0 9.7 10 0 0 10 10 10 3 Ankyrin repeat GlcNAc PF11397.8 RLN84070.1 - 3.7e-46 158.2 0.0 7.2e-40 137.5 0.1 2.5 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Alpha_kinase PF02816.18 RLN84072.1 - 5.6e-51 173.3 0.0 7.6e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family SHOCT PF09851.9 RLN84072.1 - 0.0045 16.7 0.0 0.0093 15.7 0.0 1.6 1 0 0 1 1 1 1 Short C-terminal domain Folliculin PF11704.8 RLN84072.1 - 0.048 13.5 0.1 4.1 7.2 0.1 2.2 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport MtN3_slv PF03083.16 RLN84127.1 - 8.5e-32 109.1 28.0 3.7e-12 46.1 5.4 3.4 4 0 0 4 4 4 3 Sugar efflux transporter for intercellular exchange DUF3165 PF11364.8 RLN84127.1 - 6.6 7.2 10.6 1.2 9.6 1.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3165) 4HBT_2 PF13279.6 RLN84128.1 - 2e-06 28.3 0.1 2.7e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Pentapeptide PF00805.22 RLN84128.1 - 0.098 12.3 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) NAD_binding_1 PF00175.21 RLN84130.1 - 7.9e-29 100.5 0.0 1.3e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 RLN84130.1 - 2.8e-26 91.8 0.0 4.2e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 RLN84130.1 - 0.00016 21.9 0.0 0.00094 19.3 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ribosomal_L21p PF00829.21 RLN84131.1 - 7.7e-34 116.0 3.2 9.4e-34 115.7 3.2 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein TPR_1 PF00515.28 RLN84132.1 - 3.4e-23 80.4 12.1 2.6e-06 27.0 0.0 8.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 RLN84132.1 - 2.4e-17 61.6 31.8 6.5e-06 25.9 0.0 10.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 RLN84132.1 - 8.4e-12 44.6 0.5 0.0072 16.0 0.0 6.1 4 2 2 6 6 6 3 TPR repeat TPR_8 PF13181.6 RLN84132.1 - 2.3e-11 43.0 10.0 0.46 10.8 0.0 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 RLN84132.1 - 1.1e-10 41.4 52.0 1.2e-05 25.3 5.3 9.9 7 2 4 11 11 11 5 Tetratricopeptide repeat TPR_12 PF13424.6 RLN84132.1 - 2.9e-08 33.9 35.8 6.2e-05 23.2 0.5 8.6 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN84132.1 - 5.9e-05 23.2 0.4 3.1 8.4 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN84132.1 - 0.00037 21.1 5.8 0.00037 21.1 5.8 9.3 10 1 0 10 10 7 4 Tetratricopeptide repeat NTP_transf_2 PF01909.23 RLN84132.1 - 0.0019 18.4 0.0 0.017 15.4 0.0 2.5 2 0 0 2 2 2 1 Nucleotidyltransferase domain TPR_19 PF14559.6 RLN84132.1 - 0.011 16.3 33.3 0.017 15.6 0.0 8.2 6 3 4 10 10 10 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN84132.1 - 0.095 13.4 26.5 0.13 12.9 0.1 8.2 9 0 0 9 9 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN84132.1 - 0.48 10.7 8.2 0.81 10.0 1.4 3.4 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 14-3-3 PF00244.20 RLN84133.1 - 4.7e-97 323.8 1.6 5.4e-97 323.7 1.6 1.0 1 0 0 1 1 1 1 14-3-3 protein FYVE_2 PF02318.16 RLN84135.1 - 0.063 13.5 4.8 0.11 12.7 4.8 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger His_Phos_1 PF00300.22 RLN84136.1 - 1.4e-15 57.5 0.2 1.3e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) PH PF00169.29 RLN84136.1 - 2.7e-07 31.1 0.0 5e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 PH domain RRM_7 PF16367.5 RLN84137.1 - 0.0071 16.4 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif RRM_1 PF00076.22 RLN84137.1 - 0.07 13.0 0.1 0.58 10.0 0.0 2.6 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 RLN84138.1 - 1e-06 29.0 3.0 1e-06 29.0 3.0 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN84138.1 - 4.3e-06 26.5 4.5 1.3e-05 25.0 4.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN84138.1 - 4.3e-05 23.4 3.8 0.0001 22.2 3.4 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 RLN84138.1 - 0.00034 20.8 3.3 0.0012 19.1 3.3 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RLN84138.1 - 0.0015 18.3 3.6 0.0035 17.2 3.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN84138.1 - 0.0022 18.0 2.1 0.0053 16.8 2.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 RLN84138.1 - 0.0037 17.0 0.5 0.01 15.5 0.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 RLN84138.1 - 0.017 14.8 1.1 0.017 14.8 1.1 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 RLN84138.1 - 0.02 14.7 2.8 0.048 13.5 2.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 RLN84138.1 - 0.14 12.2 0.1 0.35 10.9 0.1 1.7 1 1 0 1 1 1 0 PX domain PHD PF00628.29 RLN84138.1 - 0.26 11.2 2.5 0.59 10.1 2.5 1.7 1 0 0 1 1 1 0 PHD-finger zf-C3H2C3 PF17122.5 RLN84138.1 - 0.4 10.8 3.7 1.1 9.3 3.7 1.8 1 1 0 1 1 1 0 Zinc-finger Prok-RING_1 PF14446.6 RLN84138.1 - 2.2 8.3 6.1 0.78 9.7 0.8 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.10 RLN84138.1 - 3.1 8.0 5.0 0.89 9.7 1.0 2.1 2 0 0 2 2 2 0 Zinc ribbon domain CxC6 PF18721.1 RLN84140.1 - 0.23 11.7 18.9 0.52 10.6 5.8 3.2 1 1 1 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases MFS_1 PF07690.16 RLN84141.1 - 0.00024 20.2 7.5 0.00032 19.7 7.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Dicty_CAR PF05462.11 RLN84141.1 - 0.19 10.8 4.5 0.65 9.1 4.0 2.1 1 1 1 2 2 2 0 Slime mold cyclic AMP receptor MFS_1 PF07690.16 RLN84142.1 - 8.3e-19 67.7 27.1 8.3e-19 67.7 27.1 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 RLN84143.1 - 2.1e-17 63.1 21.3 2.1e-17 63.1 21.3 2.2 2 1 1 3 3 3 1 Major Facilitator Superfamily ATP19 PF11022.8 RLN84143.1 - 0.14 12.5 0.1 0.58 10.6 0.1 2.1 1 0 0 1 1 1 0 ATP synthase subunit K ELFV_dehydrog PF00208.21 RLN84144.1 - 3e-56 190.9 0.0 3.5e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 RLN84144.1 - 1.8e-29 102.2 0.0 4.1e-27 94.6 0.0 2.5 3 0 0 3 3 3 2 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 RLN84144.1 - 0.0047 17.4 0.0 0.0072 16.7 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Oxidored_nitro PF00148.19 RLN84144.1 - 0.047 12.4 0.0 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase 2-Hacid_dh_C PF02826.19 RLN84144.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase PF00069.25 RLN84145.1 - 2.2e-13 50.2 0.0 3.8e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Elicitin PF00964.17 RLN84145.1 - 0.0028 17.7 0.1 0.0028 17.7 0.1 2.4 2 0 0 2 2 2 1 Elicitin DUF1180 PF06679.12 RLN84145.1 - 0.16 12.3 6.9 0.35 11.3 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) TMEM154 PF15102.6 RLN84145.1 - 0.55 10.1 4.8 0.55 10.1 0.0 2.7 2 0 0 2 2 2 0 TMEM154 protein family HHH_3 PF12836.7 RLN84147.1 - 9.3e-44 147.5 0.1 4.1e-14 52.6 0.0 3.2 3 0 0 3 3 3 3 Helix-hairpin-helix motif PsbU PF06514.11 RLN84147.1 - 6.3e-22 77.4 0.0 4e-08 33.1 0.0 3.1 3 0 0 3 3 3 3 Photosystem II 12 kDa extrinsic protein (PsbU) HHH PF00633.23 RLN84147.1 - 1.4e-16 59.4 4.6 4.9e-05 23.0 0.0 6.0 6 0 0 6 6 6 4 Helix-hairpin-helix motif HHH_5 PF14520.6 RLN84147.1 - 4.4e-12 46.4 3.4 0.0009 19.8 0.1 5.8 6 0 0 6 6 6 3 Helix-hairpin-helix domain HHH_2 PF12826.7 RLN84147.1 - 7e-10 38.9 0.4 0.016 15.2 0.0 5.0 3 2 1 5 5 5 2 Helix-hairpin-helix motif HHH_8 PF14716.6 RLN84147.1 - 5.3e-08 33.1 0.7 0.03 14.7 0.0 5.3 4 2 2 6 6 6 1 Helix-hairpin-helix domain IMS_HHH PF11798.8 RLN84147.1 - 2.6e-06 27.4 0.4 0.68 10.4 0.0 5.3 6 0 0 6 6 6 1 IMS family HHH motif HHH_6 PF14579.6 RLN84147.1 - 2.2e-05 24.6 0.1 0.9 9.8 0.0 3.7 3 1 0 3 3 3 1 Helix-hairpin-helix motif Transposase_20 PF02371.16 RLN84147.1 - 0.007 16.7 1.5 2.4 8.5 0.0 3.8 3 3 2 5 5 5 1 Transposase IS116/IS110/IS902 family Cdd1 PF11731.8 RLN84147.1 - 0.018 15.3 0.0 0.78 10.0 0.0 2.8 2 1 0 2 2 2 0 Pathogenicity locus Sirohm_synth_M PF14824.6 RLN84147.1 - 0.2 11.1 0.6 49 3.5 0.1 3.5 3 0 0 3 3 3 0 Sirohaem biosynthesis protein central FYVE PF01363.21 RLN84148.1 - 0.092 12.9 8.6 0.19 11.9 8.6 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_5 PF14634.6 RLN84148.1 - 0.29 11.1 11.6 0.52 10.3 11.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain HHH_3 PF12836.7 RLN84149.1 - 7.5e-30 103.0 0.1 3.9e-14 52.7 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH PF00633.23 RLN84149.1 - 7.5e-18 63.4 0.5 0.00069 19.4 0.0 4.6 4 0 0 4 4 4 4 Helix-hairpin-helix motif PsbU PF06514.11 RLN84149.1 - 3e-13 49.6 0.0 1.3e-06 28.3 0.0 2.3 1 1 1 2 2 2 2 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_5 PF14520.6 RLN84149.1 - 9.6e-09 35.7 1.1 0.029 15.0 0.1 4.0 3 1 0 3 3 3 2 Helix-hairpin-helix domain Exo_endo_phos PF03372.23 RLN84149.1 - 1.2e-07 31.5 0.0 3.8e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HHH_2 PF12826.7 RLN84149.1 - 2.3e-07 30.8 0.2 0.13 12.3 0.0 4.2 3 1 1 4 4 4 2 Helix-hairpin-helix motif HHH_8 PF14716.6 RLN84149.1 - 4.9e-05 23.6 0.3 2.7 8.4 0.0 4.3 2 2 2 4 4 4 2 Helix-hairpin-helix domain Transposase_20 PF02371.16 RLN84149.1 - 0.05 13.9 0.0 25 5.2 0.0 3.3 3 0 0 3 3 3 0 Transposase IS116/IS110/IS902 family EF-hand_1 PF00036.32 RLN84151.1 - 2.5e-23 79.8 7.5 4.5e-07 29.0 0.5 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 RLN84151.1 - 1.1e-18 67.5 4.9 2e-12 47.3 0.4 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN84151.1 - 4.1e-16 57.5 7.6 1.9e-05 24.3 0.0 4.6 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 RLN84151.1 - 5.5e-13 47.8 5.5 0.00013 21.3 0.3 3.9 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RLN84151.1 - 1.3e-12 47.4 5.9 3.5e-06 26.7 0.2 3.4 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 RLN84151.1 - 7.2e-06 26.2 0.1 0.00037 20.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_11 PF08976.11 RLN84151.1 - 0.011 16.5 0.1 0.65 10.9 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain FGAR-AT_linker PF18072.1 RLN84151.1 - 0.031 14.8 0.0 0.1 13.2 0.0 1.9 1 1 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase linker domain SurA_N_3 PF13624.6 RLN84151.1 - 0.042 13.7 0.2 0.069 12.9 0.2 1.3 1 0 0 1 1 1 0 SurA N-terminal domain UPF0154 PF03672.13 RLN84151.1 - 0.18 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) GCIP PF13324.6 RLN84152.1 - 1.8e-17 63.8 3.4 4.8e-10 39.5 1.8 2.1 2 0 0 2 2 2 2 Grap2 and cyclin-D-interacting zf-C3HC4 PF00097.25 RLN84153.1 - 6.7e-08 32.3 10.3 6.7e-08 32.3 10.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RLN84153.1 - 2.3e-07 30.8 11.6 2.3e-07 30.8 11.6 2.2 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 RLN84153.1 - 3.7e-07 29.9 12.1 3.7e-07 29.9 12.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN84153.1 - 2.6e-05 24.1 13.2 2.6e-05 24.1 13.2 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RLN84153.1 - 2.8e-05 23.9 13.3 2.8e-05 23.9 13.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 RLN84153.1 - 2.9e-05 23.8 4.6 2.9e-05 23.8 4.6 2.4 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 RLN84153.1 - 0.00013 21.9 16.8 0.00038 20.4 16.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 RLN84153.1 - 0.00015 22.0 12.0 0.00015 22.0 12.0 2.6 2 0 0 2 2 2 1 Ring finger domain U-box PF04564.15 RLN84153.1 - 0.00047 20.3 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-ANAPC11 PF12861.7 RLN84153.1 - 0.0022 18.0 14.6 0.043 13.9 8.3 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RanBP PF00641.18 RLN84153.1 - 0.018 14.4 7.4 0.068 12.5 7.4 2.0 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Radical_SAM PF04055.21 RLN84154.1 - 2.8e-12 47.3 0.0 5.2e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 RLN84154.1 - 0.00045 20.3 0.0 0.00094 19.3 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 RLN84154.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF547 PF04784.14 RLN84155.1 - 1.6e-21 76.6 0.0 3.8e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 NTP_transf_2 PF01909.23 RLN84156.1 - 1.1e-08 35.2 0.0 2.1e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 RLN84156.1 - 3e-06 27.3 0.0 6.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase tRNA_NucTransf2 PF09249.11 RLN84156.1 - 0.0093 16.2 0.0 0.56 10.5 0.0 2.6 2 0 0 2 2 2 1 tRNA nucleotidyltransferase, second domain DNA_pol_B_palm PF14792.6 RLN84156.1 - 0.048 13.9 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase beta palm Polbeta PF18765.1 RLN84156.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase CPDase PF07823.11 RLN84157.1 - 0.0036 17.0 0.0 0.004 16.9 0.0 1.3 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein PCO_ADO PF07847.12 RLN84158.1 - 5.1e-13 48.9 0.8 1.4e-12 47.5 0.8 1.8 1 0 0 1 1 1 1 PCO_ADO Med3 PF11593.8 RLN84158.1 - 0.39 9.9 11.9 5.5 6.1 7.2 2.7 3 0 0 3 3 3 0 Mediator complex subunit 3 fungal Ank_4 PF13637.6 RLN84222.1 - 1e-34 118.5 19.8 1.5e-06 28.6 0.0 10.5 6 3 4 12 12 11 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN84222.1 - 1.6e-31 108.7 22.6 8.4e-08 32.7 0.1 5.8 1 1 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN84222.1 - 7e-26 90.0 22.1 0.0026 18.1 0.0 11.8 4 1 8 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN84222.1 - 5.6e-19 66.2 15.0 0.8 10.5 0.0 13.6 13 1 1 14 14 14 2 Ankyrin repeat DUF4411 PF14367.6 RLN84222.1 - 0.0098 15.8 0.6 2.3 8.1 0.0 3.7 2 1 2 4 4 4 1 Domain of unknown function (DUF4411) DUF3447 PF11929.8 RLN84222.1 - 0.034 14.1 0.1 31 4.6 0.0 4.4 4 1 1 5 5 5 0 Domain of unknown function (DUF3447) Ank PF00023.30 RLN84222.1 - 0.068 13.6 3.7 2.2e+02 2.5 0.2 6.6 3 2 2 5 5 5 0 Ankyrin repeat Helicase_PWI PF18149.1 RLN84222.1 - 0.17 12.0 0.3 7.5 6.8 0.1 3.5 1 1 4 5 5 5 0 N-terminal helicase PWI domain CNOT1_HEAT PF16418.5 RLN84222.1 - 0.23 11.5 7.6 3.5 7.7 0.1 5.1 4 2 1 6 6 6 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Pneumo_M2 PF07380.11 RLN84222.1 - 0.69 10.2 2.0 39 4.6 0.1 2.9 2 1 0 2 2 2 0 Pneumovirus M2 protein Pyrid_oxidase_2 PF13883.6 RLN84222.1 - 3.4 7.6 9.9 14 5.6 0.6 3.9 4 0 0 4 4 4 0 Pyridoxamine 5'-phosphate oxidase Ank_4 PF13637.6 RLN84223.1 - 0.043 14.4 0.1 0.46 11.1 0.0 1.8 1 1 1 2 2 2 0 Ankyrin repeats (many copies) HSDR_N_2 PF13588.6 RLN84223.1 - 0.056 13.4 0.0 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Pex24p PF06398.11 RLN84224.1 - 1.2e-13 50.8 0.7 1.4e-13 50.6 0.7 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin VASt PF16016.5 RLN84224.1 - 6.2e-11 42.9 0.0 9.5e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain Rrp44_S1 PF17215.3 RLN84225.1 - 0.016 15.1 1.9 0.021 14.8 0.3 1.8 1 1 1 2 2 2 0 S1 domain TMA7 PF09072.10 RLN84225.1 - 0.27 12.1 3.8 0.31 11.9 3.8 1.1 1 0 0 1 1 1 0 Translation machinery associated TMA7 DUF2723 PF11028.8 RLN84226.1 - 6.4e-22 78.3 15.6 1.5e-21 77.0 10.7 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF2723) PMT_2 PF13231.6 RLN84226.1 - 6.9e-06 26.4 7.3 6.9e-06 26.4 7.3 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Peptidase_A24 PF01478.18 RLN84226.1 - 8.8 6.8 10.9 2.7 8.4 3.9 3.1 2 2 0 2 2 2 0 Type IV leader peptidase family IF-2B PF01008.17 RLN84227.1 - 5.9e-57 193.0 0.0 1.2e-56 192.0 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF1729 PF08354.10 RLN84228.1 - 0.15 10.9 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) Pkinase PF00069.25 RLN84229.1 - 1.7e-06 27.6 0.0 2.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF294_C PF10335.9 RLN84229.1 - 0.048 13.4 0.8 0.083 12.7 0.8 1.3 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain Pkinase_Tyr PF07714.17 RLN84230.1 - 8e-56 189.2 0.0 7.1e-44 150.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN84230.1 - 8.3e-51 172.9 0.0 6.3e-39 133.9 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Arm PF00514.23 RLN84230.1 - 2.7e-10 39.9 4.9 2 8.6 0.0 8.0 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat Kinase-like PF14531.6 RLN84230.1 - 8.2e-05 22.1 0.0 0.016 14.6 0.0 2.4 2 0 0 2 2 2 2 Kinase-like HEAT_2 PF13646.6 RLN84230.1 - 0.00075 19.8 8.6 0.031 14.7 0.7 4.3 2 2 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 RLN84230.1 - 0.01 16.3 7.1 0.37 11.3 0.1 4.5 5 0 0 5 5 5 0 HEAT-like repeat Atx10homo_assoc PF09759.9 RLN84230.1 - 0.019 15.0 0.2 20 5.3 0.0 3.8 3 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain Pkinase_fungal PF17667.1 RLN84230.1 - 0.025 13.3 0.0 0.045 12.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase HEAT PF02985.22 RLN84230.1 - 0.29 11.5 4.5 7 7.2 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat MMR_HSR1 PF01926.23 RLN84231.1 - 1.4e-12 47.7 0.0 5.1e-12 45.9 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN84231.1 - 4.7e-05 23.0 0.0 0.00051 19.6 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RLN84231.1 - 0.0018 18.2 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 RLN84231.1 - 0.014 14.8 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 AIG1 family MeaB PF03308.16 RLN84231.1 - 0.049 12.6 0.1 0.081 11.9 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 RLN84231.1 - 0.11 12.5 0.4 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 Dynamin family Inhibitor_I53 PF11714.8 RLN84231.1 - 4.1 7.7 7.6 0.22 11.7 1.1 2.2 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Snurportin1 PF11538.8 RLN84233.1 - 0.0047 17.1 1.4 0.0047 17.1 1.4 2.0 2 0 0 2 2 2 1 Snurportin1 CLP1_P PF16575.5 RLN84234.1 - 2.8e-54 183.8 0.0 8.8e-54 182.2 0.0 1.8 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 RLN84234.1 - 9.3e-31 105.9 0.0 1.4e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 RLN84234.1 - 1.7e-07 31.6 0.0 3.2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 RLN84234.1 - 0.029 14.2 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 RLN84234.1 - 0.029 13.9 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 RLN84234.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PPR_2 PF13041.6 RLN84235.1 - 6.1e-36 122.4 4.5 6.9e-12 45.4 0.0 9.0 8 2 3 11 11 11 6 PPR repeat family PPR_3 PF13812.6 RLN84235.1 - 8.6e-33 112.2 0.0 4.9e-07 29.7 0.0 6.7 5 1 1 6 6 6 5 Pentatricopeptide repeat domain PPR PF01535.20 RLN84235.1 - 2.3e-26 90.1 10.1 1.4e-07 31.2 0.1 12.7 13 1 0 13 13 13 4 PPR repeat PPR_1 PF12854.7 RLN84235.1 - 7.2e-22 76.8 4.5 1.1e-08 34.6 0.0 7.8 8 0 0 8 8 8 4 PPR repeat PPR_long PF17177.4 RLN84235.1 - 1.6e-15 57.0 3.3 0.00055 19.4 0.0 4.6 3 2 1 4 4 4 4 Pentacotripeptide-repeat region of PRORP COX5A PF02284.16 RLN84235.1 - 2.6e-05 24.2 0.0 0.27 11.3 0.0 4.0 2 1 2 4 4 4 1 Cytochrome c oxidase subunit Va ATP13 PF12921.7 RLN84235.1 - 0.003 17.4 0.2 1.2 9.0 0.0 4.1 3 1 0 4 4 4 1 Mitochondrial ATPase expression MRP-S27 PF10037.9 RLN84235.1 - 0.017 14.0 0.8 0.54 9.1 0.1 2.9 3 1 0 3 3 3 0 Mitochondrial 28S ribosomal protein S27 RPAP3_C PF13877.6 RLN84235.1 - 0.035 14.6 0.3 0.25 11.9 0.0 2.4 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 Clathrin PF00637.20 RLN84235.1 - 0.11 12.4 4.1 3.9 7.3 0.1 4.4 4 2 1 5 5 5 0 Region in Clathrin and VPS SPOB_a PF14689.6 RLN84235.1 - 0.11 12.2 2.3 6.6 6.5 0.1 3.6 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain Coatomer_E PF04733.14 RLN84235.1 - 0.14 11.5 4.9 13 5.1 0.0 4.1 5 0 0 5 5 5 0 Coatomer epsilon subunit TPR_19 PF14559.6 RLN84235.1 - 0.26 11.8 5.2 16 6.1 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat RFC1 PF08519.12 RLN84281.1 - 1.1e-15 58.2 0.0 1.5e-09 38.2 0.0 2.3 2 0 0 2 2 2 2 Replication factor RFC1 C terminal domain GARS_A PF01071.19 RLN84281.1 - 0.099 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RPAP2_Rtr1 PF04181.13 RLN84282.1 - 0.028 14.7 0.1 0.037 14.3 0.1 1.2 1 0 0 1 1 1 0 Rtr1/RPAP2 family Mg_trans_NIPA PF05653.14 RLN84283.1 - 6.1e-32 110.9 18.5 1.5e-30 106.4 18.5 2.0 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 RLN84283.1 - 0.0092 16.2 7.2 0.0092 16.2 7.2 3.4 2 2 1 3 3 3 1 EamA-like transporter family Acyltransferase PF01553.21 RLN84284.1 - 8e-17 61.1 0.0 3.9e-16 58.9 0.0 2.1 2 0 0 2 2 2 1 Acyltransferase DUF3007 PF11460.8 RLN84284.1 - 0.064 13.5 0.0 10 6.5 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) CBM_1 PF00734.18 RLN84285.1 - 1e-07 31.8 0.7 1.5e-07 31.2 0.7 1.2 1 0 0 1 1 1 1 Fungal cellulose binding domain Alpha_GJ PF03229.13 RLN84285.1 - 0.099 13.2 2.4 0.14 12.7 2.4 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J DIM PF08194.12 RLN84285.1 - 0.59 10.4 2.2 1 9.6 2.2 1.4 1 0 0 1 1 1 0 DIM protein CBM_1 PF00734.18 RLN84286.1 - 1.9e-06 27.7 3.5 2.7e-06 27.2 3.5 1.2 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF2125 PF09898.9 RLN84286.1 - 0.049 13.3 0.1 0.058 13.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2125) TMEM154 PF15102.6 RLN84287.1 - 0.056 13.3 0.1 0.056 13.3 0.1 4.0 2 1 3 5 5 5 0 TMEM154 protein family Peptidase_M56 PF05569.11 RLN84287.1 - 0.85 8.8 1.5 0.86 8.7 0.0 1.7 2 0 0 2 2 2 0 BlaR1 peptidase M56 RIFIN PF02009.16 RLN84287.1 - 3.6 7.4 11.2 13 5.6 0.1 2.2 2 0 0 2 2 2 0 Rifin RRM_1 PF00076.22 RLN84288.1 - 7.4e-15 54.5 0.0 7.6e-08 32.1 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.11 RLN84288.1 - 0.0072 15.8 0.0 0.021 14.3 0.0 1.8 1 0 0 1 1 1 1 Lsm interaction motif DUF3887 PF13026.6 RLN84288.1 - 0.047 14.5 0.2 0.22 12.4 0.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3887) RRM_5 PF13893.6 RLN84288.1 - 0.065 12.8 0.0 2.8 7.6 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KxDL PF10241.9 RLN84289.1 - 0.16 12.3 6.6 0.35 11.2 6.6 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein Spt46 PF17734.1 RLN84289.1 - 2.9 7.6 7.0 8.1 6.2 7.0 1.8 1 0 0 1 1 1 0 Spermatogenesis-associated protein 46 RSN1_7TM PF02714.15 RLN84290.1 - 3.3e-08 33.2 5.9 9e-08 31.8 5.9 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 RLN84290.1 - 7e-06 26.4 2.2 0.0022 18.2 2.2 3.2 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RRM_1 PF00076.22 RLN84290.1 - 0.015 15.1 0.0 2.4 8.0 0.0 2.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PIN_8 PF18476.1 RLN84290.1 - 0.14 12.0 1.5 0.35 10.7 1.5 1.6 1 0 0 1 1 1 0 PIN like domain IncD PF17628.2 RLN84290.1 - 0.19 11.5 4.8 0.045 13.5 0.3 2.4 2 0 0 2 2 2 0 Inclusion membrane protein D Anoctamin PF04547.12 RLN84290.1 - 6.6 5.4 7.1 0.41 9.4 0.2 2.4 3 0 0 3 3 3 0 Calcium-activated chloride channel CBM_1 PF00734.18 RLN84291.1 - 0.00029 20.7 7.3 0.11 12.5 0.3 3.2 2 1 0 2 2 2 2 Fungal cellulose binding domain Acetyltransf_1 PF00583.25 RLN84292.1 - 9e-18 64.6 0.0 1.1e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RLN84292.1 - 1.5e-14 54.0 0.0 2e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN84292.1 - 1.7e-12 47.6 0.0 2.5e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 RLN84292.1 - 3.9e-05 23.8 0.0 4.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 RLN84292.1 - 5.6e-05 23.8 0.1 7e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN84292.1 - 0.00013 21.9 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.7 RLN84292.1 - 0.0012 19.0 0.1 0.0016 18.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF937 PF06078.11 RLN84294.1 - 0.13 12.8 1.0 0.26 11.9 0.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) Ras PF00071.22 RLN84295.1 - 2.6e-41 140.9 0.1 1.7e-20 73.2 0.0 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 RLN84295.1 - 1e-22 80.6 0.1 1.8e-18 66.9 0.0 2.3 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 RLN84295.1 - 1.1e-05 25.4 1.3 0.022 14.6 0.2 2.5 1 1 1 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 RLN84295.1 - 2.8e-05 24.2 0.0 3.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 RLN84295.1 - 6.9e-05 22.4 0.1 0.00061 19.3 0.0 2.0 1 1 1 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RLN84295.1 - 0.0037 16.7 0.0 0.011 15.1 0.1 1.6 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 RLN84295.1 - 0.0045 17.5 0.1 0.0075 16.8 0.1 1.5 1 1 0 1 1 1 1 ABC transporter SRPRB PF09439.10 RLN84295.1 - 0.0068 15.9 0.3 0.3 10.5 0.0 2.1 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 RLN84295.1 - 0.0075 16.7 0.0 0.015 15.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 RLN84295.1 - 0.014 15.1 0.0 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 RLN84295.1 - 0.019 14.1 0.1 0.037 13.2 0.1 1.4 1 1 0 1 1 1 0 G-protein alpha subunit TniB PF05621.11 RLN84295.1 - 0.043 13.2 0.0 0.17 11.3 0.0 1.9 1 1 1 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 RLN84295.1 - 0.048 13.2 0.1 0.076 12.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 RLN84295.1 - 0.053 12.7 0.1 0.26 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AP_endonuc_2 PF01261.24 RLN84295.1 - 0.067 12.6 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel AAA_5 PF07728.14 RLN84295.1 - 0.093 12.7 0.0 0.39 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 RLN84295.1 - 0.12 12.8 0.4 7.2 7.0 0.1 2.8 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 RLN84295.1 - 0.12 11.7 0.1 0.64 9.3 0.1 2.0 1 1 0 1 1 1 0 KaiC AAA_22 PF13401.6 RLN84295.1 - 0.13 12.6 0.1 0.48 10.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 RLN84295.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain SmpB PF01668.18 RLN84296.1 - 1.8e-12 47.3 0.2 5.1e-09 36.2 0.0 2.1 1 1 1 2 2 2 2 SmpB protein Tub PF01167.18 RLN84297.1 - 5.9e-28 98.2 0.0 7.3e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Tub family RSN1_7TM PF02714.15 RLN84298.1 - 4.1e-09 36.1 6.9 4.1e-09 36.1 6.9 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 RLN84298.1 - 4.9e-05 23.6 3.0 0.00038 20.8 3.0 2.2 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 RLN84298.1 - 0.0069 15.3 0.1 0.0069 15.3 0.1 2.3 4 0 0 4 4 4 1 Calcium-activated chloride channel Wtap PF17098.5 RLN84298.1 - 0.081 12.9 4.8 0.15 12.0 4.8 1.3 1 0 0 1 1 1 0 WTAP/Mum2p family Rod_cone_degen PF15201.6 RLN84298.1 - 4.7 7.4 6.7 0.88 9.7 0.2 2.9 3 0 0 3 3 3 0 Progressive rod-cone degeneration Aa_trans PF01490.18 RLN84371.1 - 6e-68 229.4 21.5 7.5e-68 229.1 21.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SAYSvFN PF10260.9 RLN84371.1 - 0.4 10.6 2.4 0.58 10.1 0.7 2.1 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) LRR_8 PF13855.6 RLN84372.1 - 2.7e-19 68.7 18.4 1.5e-10 40.6 3.5 4.4 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 RLN84372.1 - 1.8e-14 53.6 22.0 0.00069 20.0 1.6 6.0 2 2 4 7 7 7 6 Leucine Rich repeats (2 copies) TFIIA PF03153.13 RLN84372.1 - 0.00017 21.7 14.8 0.00017 21.7 14.8 2.0 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 RLN84372.1 - 0.021 14.2 26.9 0.043 13.2 26.9 1.5 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 RLN84372.1 - 0.1 10.6 37.7 0.18 9.9 37.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi WW PF00397.26 RLN84372.1 - 0.23 11.6 1.9 0.5 10.5 1.9 1.6 1 0 0 1 1 1 0 WW domain LRR_6 PF13516.6 RLN84372.1 - 0.45 10.7 10.9 6.5 7.1 0.2 4.7 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 RLN84372.1 - 1.1 10.0 17.0 49 5.1 0.1 7.4 8 0 0 8 8 7 0 Leucine Rich Repeat PPP4R2 PF09184.11 RLN84372.1 - 1.1 8.7 23.7 2.4 7.7 23.7 1.5 1 0 0 1 1 1 0 PPP4R2 DUF913 PF06025.12 RLN84372.1 - 2.9 6.8 5.0 5.3 5.9 5.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 RLN84372.1 - 3.1 6.0 23.0 0.031 12.6 14.7 1.8 2 0 0 2 2 2 0 CDC45-like protein SAPS PF04499.15 RLN84372.1 - 5.2 5.7 13.0 8.3 5.1 13.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2457 PF10446.9 RLN84372.1 - 6.4 5.8 37.3 17 4.4 37.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) AAA PF00004.29 RLN84373.1 - 1.5e-15 57.8 0.0 3.1e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN84373.1 - 7.3e-05 23.2 1.9 0.00039 20.8 1.9 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 RLN84373.1 - 0.0041 17.1 0.0 0.02 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RLN84373.1 - 0.0072 16.6 0.1 0.033 14.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 RLN84373.1 - 0.0096 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 RLN84373.1 - 0.019 15.2 0.1 0.05 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 RLN84373.1 - 0.027 14.2 0.0 0.12 12.1 0.0 2.0 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 RLN84373.1 - 0.029 14.3 0.1 0.14 12.0 0.0 2.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 RLN84373.1 - 0.032 14.2 0.0 0.084 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 RLN84373.1 - 0.036 13.4 0.1 0.085 12.2 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 RLN84373.1 - 0.056 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF815 PF05673.13 RLN84373.1 - 0.064 12.4 0.1 0.12 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DAP3 PF10236.9 RLN84373.1 - 0.085 12.0 1.2 0.51 9.4 0.0 2.6 2 2 1 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 RLN84373.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 RLN84373.1 - 0.16 12.3 0.0 0.44 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NPR1_interact PF15699.5 RLN84373.1 - 0.43 11.2 2.0 0.34 11.5 0.4 1.6 2 0 0 2 2 1 0 NPR1 interacting DMRL_synthase PF00885.19 RLN84374.1 - 7.2e-12 45.3 0.2 9.1e-12 45.0 0.2 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Dimer_Tnp_hAT PF05699.14 RLN84375.1 - 0.00016 21.4 0.1 0.00031 20.5 0.1 1.6 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region RINGv PF12906.7 RLN84376.1 - 2.3e-13 50.0 6.1 8.5e-13 48.2 6.1 2.0 1 1 0 1 1 1 1 RING-variant domain FHA PF00498.26 RLN84376.1 - 3.1e-13 49.8 0.2 2.9e-11 43.5 0.0 2.6 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 RLN84376.1 - 1.1e-06 28.8 0.0 4.4e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_2 PF13639.6 RLN84376.1 - 0.012 15.9 7.3 0.35 11.3 8.4 2.5 1 1 1 2 2 2 0 Ring finger domain cNMP_binding PF00027.29 RLN84377.1 - 1.8e-07 31.1 0.0 3.3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain ABC2_membrane PF01061.24 RLN84438.1 - 4.7e-66 222.2 71.1 1.4e-39 135.7 25.6 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN84438.1 - 8.6e-34 117.0 0.0 9.9e-17 61.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 RLN84438.1 - 3.2e-11 43.0 45.4 2e-07 30.5 11.7 3.2 2 2 0 2 2 2 2 ABC-2 family transporter protein PDR_CDR PF06422.12 RLN84438.1 - 2e-09 37.2 9.6 2.1e-08 34.0 0.0 3.7 4 0 0 4 4 3 2 CDR ABC transporter AAA_21 PF13304.6 RLN84438.1 - 1.2e-07 31.8 0.0 0.081 12.7 0.0 3.2 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN84438.1 - 1.9e-06 27.9 1.4 0.0062 16.5 0.2 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 RLN84438.1 - 5.2e-06 26.9 0.1 0.13 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 RLN84438.1 - 2e-05 24.2 6.4 0.025 14.3 1.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 RLN84438.1 - 4.9e-05 22.7 0.3 0.0099 15.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 RLN84438.1 - 8.5e-05 22.8 0.1 0.29 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain PDR_assoc PF08370.11 RLN84438.1 - 0.00042 20.0 12.2 0.0098 15.6 0.2 3.5 3 0 0 3 3 2 2 Plant PDR ABC transporter associated AAA_25 PF13481.6 RLN84438.1 - 0.00046 19.8 0.3 0.4 10.2 0.1 2.6 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 RLN84438.1 - 0.00062 19.7 0.0 1.6 8.6 0.0 3.2 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 RLN84438.1 - 0.0022 17.7 0.4 0.86 9.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RLN84438.1 - 0.0026 18.3 0.0 2.7 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 RLN84438.1 - 0.0037 16.7 2.5 8.6 5.7 0.1 3.9 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 RLN84438.1 - 0.0043 17.5 0.1 6.6 7.2 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 RLN84438.1 - 0.0045 17.1 0.6 1.5 8.9 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 RLN84438.1 - 0.01 15.8 1.0 3.9 7.3 0.2 2.5 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 RLN84438.1 - 0.016 15.7 4.3 0.32 11.5 0.4 2.3 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 RLN84438.1 - 0.063 13.2 0.2 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 cobW PF02492.19 RLN84438.1 - 0.066 12.8 1.7 1.7 8.2 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 RLN84438.1 - 0.071 13.3 0.2 12 6.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 RLN84438.1 - 0.071 13.5 0.2 11 6.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 RLN84438.1 - 0.093 12.8 2.9 3.9 7.5 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_5 PF07728.14 RLN84438.1 - 0.094 12.7 0.3 2.2 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 RLN84438.1 - 0.11 12.2 1.0 16 5.1 0.5 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 RLN84438.1 - 0.15 12.2 0.1 13 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 RLN84438.1 - 0.15 11.8 0.2 0.43 10.3 0.0 1.8 2 0 0 2 2 2 0 Virulence-associated protein E TsaE PF02367.17 RLN84438.1 - 0.39 10.7 1.2 1.7 8.6 0.2 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 RLN84438.1 - 0.51 10.1 4.0 4.4 7.0 0.3 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_ATPase PF09818.9 RLN84438.1 - 0.75 8.5 2.5 1.4 7.7 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_28 PF13521.6 RLN84438.1 - 0.79 10.0 3.6 19 5.4 0.8 2.8 3 0 0 3 3 2 0 AAA domain MFS_1 PF07690.16 RLN84439.1 - 3.2e-09 36.2 4.5 3.6e-09 36.0 4.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN84439.1 - 3.2e-05 23.0 11.3 4.2e-05 22.6 11.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF5464 PF17552.2 RLN84439.1 - 1.8 8.9 13.8 0.098 12.9 7.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5464) Crystall_3 PF08964.10 RLN84440.1 - 0.0005 20.2 1.1 0.55 10.4 0.1 3.4 3 1 0 3 3 3 2 Beta/Gamma crystallin Myb_DNA-binding PF00249.31 RLN84441.1 - 8.3e-09 35.5 0.1 0.0018 18.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN84441.1 - 2.4e-07 30.9 0.0 0.0011 19.2 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 RLN84441.1 - 0.0032 17.5 0.4 9.1 6.4 0.1 3.2 2 1 1 3 3 3 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 RLN84441.1 - 0.078 13.4 0.3 6.7 7.2 0.4 2.6 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain CDC48_N PF02359.18 RLN84444.1 - 7.7e-14 51.6 0.1 1.2e-13 51.0 0.1 1.3 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.17 RLN84444.1 - 7.2e-09 35.3 0.0 1.7e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Molydop_binding PF01568.21 RLN84444.1 - 0.025 14.6 0.1 0.038 14.0 0.1 1.3 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain PEX-2N PF09263.10 RLN84444.1 - 0.19 12.1 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal FYVE PF01363.21 RLN84445.1 - 9.1e-05 22.5 12.0 0.00021 21.4 12.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN84445.1 - 0.016 15.4 6.0 0.058 13.6 6.0 2.0 1 0 0 1 1 1 0 FYVE-type zinc finger K-cyclin_vir_C PF09080.10 RLN84445.1 - 0.089 13.2 0.0 0.24 11.9 0.0 1.7 1 0 0 1 1 1 0 K cyclin, C terminal RNase_PH PF01138.21 RLN84448.1 - 4.6e-16 59.5 0.3 3.8e-15 56.5 0.2 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RLN84448.1 - 2.4e-14 53.1 0.1 4.2e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 UFD1 PF03152.14 RLN84449.1 - 1.3e-33 115.9 0.0 2.1e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 UBX PF00789.20 RLN84449.1 - 2e-14 53.6 0.0 5.3e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 UBX domain NAGLU PF05089.12 RLN84452.1 - 6.9e-111 370.4 0.2 9.2e-111 370.0 0.2 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 RLN84452.1 - 8.2e-82 274.7 4.8 1.2e-81 274.1 4.8 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain Glyco_hydro38C2 PF17677.1 RLN84453.1 - 0.0058 16.7 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain COX15-CtaA PF02628.15 RLN84516.1 - 9.4e-90 301.0 4.3 6.1e-53 180.0 0.6 2.0 1 1 1 2 2 2 2 Cytochrome oxidase assembly protein Toxin_29 PF08116.11 RLN84517.1 - 0.0049 16.8 1.0 1.5 8.9 0.2 3.8 3 0 0 3 3 3 1 PhTx neurotoxin family DUF983 PF06170.12 RLN84517.1 - 0.05 14.0 1.6 20 5.7 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF983) YdjO PF14169.6 RLN84517.1 - 0.8 9.5 12.9 17 5.3 0.2 4.7 5 0 0 5 5 5 0 Cold-inducible protein YdjO BSMAP PF12280.8 RLN84517.1 - 1 9.5 4.3 11 6.2 0.1 2.3 2 0 0 2 2 2 0 Brain specific membrane anchored protein zf-dskA_traR PF01258.17 RLN84517.1 - 1.5 8.8 17.4 2.4 8.2 0.0 4.8 5 0 0 5 5 5 0 Prokaryotic dksA/traR C4-type zinc finger RSN1_7TM PF02714.15 RLN84518.1 - 2e-39 135.6 17.8 3.6e-39 134.7 17.8 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 RLN84518.1 - 4e-28 98.1 1.4 1.5e-27 96.3 1.4 2.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 RLN84518.1 - 1.3e-26 93.9 0.1 4.5e-17 62.8 0.0 2.3 1 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter Cytochrom_C_2 PF01322.20 RLN84521.1 - 0.06 14.2 0.0 0.082 13.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C' GDC-P PF02347.16 RLN84522.1 - 1.1e-107 360.6 0.6 1.1e-89 301.2 0.4 3.2 3 0 0 3 3 3 3 Glycine cleavage system P-protein Aminotran_5 PF00266.19 RLN84522.1 - 1.4e-08 34.1 0.2 3.2e-07 29.7 0.1 2.6 3 0 0 3 3 3 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 RLN84522.1 - 0.006 15.9 0.5 0.011 15.0 0.1 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 RLN84522.1 - 0.015 13.8 0.0 2 6.8 0.0 2.3 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme DUF4689 PF15755.5 RLN84522.1 - 0.02 14.5 0.2 0.035 13.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4689) TraI PF07057.11 RLN84522.1 - 0.083 13.0 0.8 0.3 11.2 0.0 2.3 3 0 0 3 3 3 0 DNA helicase TraI AA_permease_2 PF13520.6 RLN84523.1 - 1.3e-43 149.4 36.5 1.9e-43 148.9 36.5 1.2 1 0 0 1 1 1 1 Amino acid permease UbiA PF01040.18 RLN84524.1 - 4.1e-05 23.0 21.8 6.1e-05 22.4 19.2 1.9 1 1 1 2 2 2 2 UbiA prenyltransferase family DUF4047 PF13256.6 RLN84525.1 - 1.1 9.5 12.5 2.3 8.4 3.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Rab5-bind PF09311.11 RLN84525.1 - 3.1 7.1 34.0 40 3.5 34.1 2.4 1 1 0 1 1 1 0 Rabaptin-like protein SNF2_N PF00176.23 RLN84526.1 - 8.6e-62 208.9 0.1 1.8e-61 207.8 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN84526.1 - 3.2e-19 69.3 0.0 3.3e-18 66.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 RLN84526.1 - 1.7e-15 56.6 8.8 3.6e-08 33.2 0.2 3.1 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 RLN84526.1 - 2.9e-08 33.9 0.1 1.6e-07 31.5 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 RLN84526.1 - 0.0001 21.6 0.1 0.00032 20.0 0.1 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 UPF0121 PF03661.13 RLN84527.1 - 2.1e-54 184.5 9.5 3e-54 184.0 9.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) TPR_2 PF07719.17 RLN84527.1 - 8.2e-08 31.8 9.6 0.063 13.4 0.8 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN84527.1 - 0.00046 19.9 5.0 1.4 8.9 0.5 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.17 RLN84527.1 - 0.00082 19.8 4.6 0.078 13.4 0.7 2.5 1 1 1 2 2 2 2 Bacterial transcriptional activator domain TPR_14 PF13428.6 RLN84527.1 - 0.0035 18.0 12.4 0.28 12.1 0.1 4.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN84527.1 - 0.0058 16.9 6.5 0.011 16.0 1.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN84527.1 - 0.009 15.9 0.9 3.2 7.7 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN84527.1 - 0.033 14.8 17.0 0.086 13.5 5.3 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN84527.1 - 0.099 13.2 7.7 0.29 11.7 0.7 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 RLN84527.1 - 0.32 10.7 3.0 12 5.7 0.0 2.9 2 1 1 3 3 3 0 TPR repeat TPR_9 PF13371.6 RLN84527.1 - 3.7 7.8 7.0 2.5 8.3 2.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat GIT_CC PF16559.5 RLN84529.1 - 1.5 8.7 6.8 25 4.8 0.2 4.5 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Dict-STAT-coil PF09267.10 RLN84529.1 - 4.8 7.6 11.1 1.1 9.7 0.2 3.6 2 1 2 4 4 4 0 Dictyostelium STAT, coiled coil Helicase_C_2 PF13307.6 RLN84530.1 - 1.8e-53 181.2 0.0 7.8e-53 179.1 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 RLN84530.1 - 8e-42 142.8 0.3 8e-42 142.8 0.3 1.8 2 0 0 2 2 2 1 DEAD_2 5-FTHF_cyc-lig PF01812.20 RLN84530.1 - 4.4e-12 46.2 0.1 4.4e-12 46.2 0.1 1.8 2 0 0 2 2 2 1 5-formyltetrahydrofolate cyclo-ligase family DEAD PF00270.29 RLN84530.1 - 2.3e-05 24.2 0.8 0.031 14.1 0.0 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 RLN84530.1 - 0.0001 22.4 0.1 0.0052 16.8 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DnaJ PF00226.31 RLN84530.1 - 0.00016 21.7 1.5 0.22 11.7 0.2 2.6 2 0 0 2 2 2 2 DnaJ domain PhoH PF02562.16 RLN84530.1 - 0.0045 16.5 0.1 2.7 7.4 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Zot PF05707.12 RLN84530.1 - 0.017 14.7 0.1 0.42 10.2 0.1 2.7 3 0 0 3 3 3 0 Zonular occludens toxin (Zot) T2SSE PF00437.20 RLN84530.1 - 0.081 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein HBB PF06777.11 RLN84530.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Helical and beta-bridge domain Amidase PF01425.21 RLN84531.1 - 5.7e-89 299.1 0.1 1.5e-88 297.8 0.1 1.6 1 1 0 1 1 1 1 Amidase ACBP PF00887.19 RLN84532.1 - 4.5e-15 55.6 0.0 9.9e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein SF-assemblin PF06705.11 RLN84532.1 - 0.0033 16.8 2.5 0.0051 16.2 2.5 1.2 1 0 0 1 1 1 1 SF-assemblin/beta giardin CREPT PF16566.5 RLN84532.1 - 0.042 14.0 3.7 0.085 13.0 3.7 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF5082 PF16888.5 RLN84532.1 - 0.1 12.9 2.4 0.22 11.8 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DUF3963 PF13124.6 RLN84532.1 - 0.11 12.5 1.8 0.23 11.5 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) Hexokinase_2 PF03727.16 RLN84532.1 - 0.19 11.1 1.5 0.33 10.4 1.5 1.3 1 0 0 1 1 1 0 Hexokinase TMF_TATA_bd PF12325.8 RLN84532.1 - 0.45 10.7 10.2 4.1 7.7 1.7 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TolA_bind_tri PF16331.5 RLN84532.1 - 2 8.6 13.3 2.5 8.3 10.0 2.3 1 1 1 2 2 2 0 TolA binding protein trimerisation Cep57_MT_bd PF06657.13 RLN84532.1 - 2.8 8.5 7.7 2.6 8.5 1.4 2.5 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 YabA PF06156.13 RLN84532.1 - 4.1 8.1 6.8 16 6.2 0.7 2.3 1 1 1 2 2 2 0 Initiation control protein YabA SDF PF00375.18 RLN84533.1 - 1.1e-57 195.9 26.4 3.2e-57 194.3 26.4 1.6 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family Fascin PF06268.13 RLN84533.1 - 0.0043 17.3 0.0 0.0072 16.5 0.0 1.3 1 0 0 1 1 1 1 Fascin domain FRG1 PF06229.12 RLN84533.1 - 0.26 11.0 0.0 0.38 10.4 0.0 1.2 1 0 0 1 1 1 0 FRG1-like domain RICTOR_V PF14668.6 RLN84533.1 - 1.3 9.3 3.4 3.1 8.1 0.0 3.0 3 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 HALZ PF02183.18 RLN84534.1 - 0.00013 22.1 1.2 0.16 12.2 0.4 2.5 1 1 1 2 2 2 2 Homeobox associated leucine zipper ZapB PF06005.12 RLN84534.1 - 0.00014 22.2 2.3 0.00028 21.3 2.3 1.6 1 0 0 1 1 1 1 Cell division protein ZapB bZIP_1 PF00170.21 RLN84534.1 - 0.00041 20.4 0.7 0.00041 20.4 0.7 2.2 2 0 0 2 2 2 1 bZIP transcription factor Atg14 PF10186.9 RLN84534.1 - 0.0059 15.7 1.0 0.0059 15.7 1.0 1.6 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 Cep57_CLD_2 PF14197.6 RLN84534.1 - 0.011 15.8 4.1 0.091 12.9 1.4 2.5 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 THOC7 PF05615.13 RLN84534.1 - 0.012 15.9 3.7 0.021 15.1 3.7 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 APG6_N PF17675.1 RLN84534.1 - 0.044 14.3 4.8 0.082 13.4 4.8 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Shugoshin_N PF07558.11 RLN84534.1 - 0.047 13.6 1.1 0.12 12.2 0.1 2.2 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region YabA PF06156.13 RLN84534.1 - 0.049 14.3 1.1 0.12 13.0 1.1 1.7 1 0 0 1 1 1 0 Initiation control protein YabA Csm1_N PF18504.1 RLN84534.1 - 0.06 13.7 1.5 0.15 12.5 1.5 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain Cnn_1N PF07989.11 RLN84534.1 - 0.065 13.4 2.2 0.13 12.4 2.2 1.6 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 RLN84534.1 - 0.092 12.5 1.1 0.19 11.5 1.1 1.6 1 0 0 1 1 1 0 Septum formation initiator MctB PF11382.8 RLN84534.1 - 0.1 12.3 1.9 0.18 11.5 1.9 1.3 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB JIP_LZII PF16471.5 RLN84534.1 - 0.12 12.5 3.1 0.24 11.6 3.1 1.5 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Macoilin PF09726.9 RLN84534.1 - 0.13 10.8 2.1 0.2 10.2 2.1 1.2 1 0 0 1 1 1 0 Macoilin family Fez1 PF06818.15 RLN84534.1 - 0.3 11.5 5.5 0.53 10.7 5.5 1.6 1 1 0 1 1 1 0 Fez1 Longin PF13774.6 RLN84535.1 - 3.3e-20 71.9 0.0 8.5e-19 67.4 0.0 2.2 1 1 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 RLN84535.1 - 7.7e-16 57.7 0.3 1.3e-15 56.9 0.3 1.4 1 0 0 1 1 1 1 Synaptobrevin COQ9 PF08511.11 RLN84535.1 - 0.028 14.2 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 COQ9 Proteasome PF00227.26 RLN84536.1 - 8.4e-30 103.7 0.0 1.4e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit DLIC PF05783.11 RLN84536.1 - 5.4e-05 22.2 0.0 0.0011 17.9 0.0 2.1 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) Roc PF08477.13 RLN84536.1 - 0.00021 21.5 0.0 0.00051 20.2 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RLN84536.1 - 0.00082 19.0 0.0 0.025 14.2 0.0 2.3 2 0 0 2 2 2 1 Ras family AAA_16 PF13191.6 RLN84536.1 - 0.0054 17.1 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 RLN84536.1 - 0.0099 15.8 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 RLN84536.1 - 0.031 14.5 0.0 0.066 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RLN84536.1 - 0.032 14.0 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 RLN84536.1 - 0.088 13.3 0.0 0.28 11.7 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 RLN84536.1 - 0.12 12.6 0.3 2.9 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain zf-RING_2 PF13639.6 RLN84613.1 - 7.2e-10 39.1 11.3 1.6e-09 37.9 11.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RLN84613.1 - 3.7e-07 30.3 9.6 9e-07 29.1 9.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RLN84613.1 - 2e-06 27.6 7.0 4e-06 26.6 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 RLN84613.1 - 3.6e-06 26.9 0.0 9.7e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 PX domain zf-RING_UBOX PF13445.6 RLN84613.1 - 7.8e-06 25.8 3.5 1.7e-05 24.7 3.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 RLN84613.1 - 1.4e-05 24.7 3.2 3e-05 23.6 3.2 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RLN84613.1 - 7.2e-05 22.6 11.3 0.00018 21.3 11.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RLN84613.1 - 0.00016 21.7 4.5 0.00039 20.4 4.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RLN84613.1 - 0.002 18.0 7.9 0.0039 17.0 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN84613.1 - 0.0091 15.9 8.5 0.018 15.0 8.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 RLN84613.1 - 0.12 12.5 8.5 0.39 10.9 8.5 1.9 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 RLN84613.1 - 0.57 10.3 9.4 1.5 9.0 9.4 1.7 1 0 0 1 1 1 0 RING-variant domain ABM PF03992.16 RLN84614.1 - 0.015 15.4 0.4 0.026 14.6 0.4 1.4 1 1 0 1 1 1 0 Antibiotic biosynthesis monooxygenase ABC2_membrane PF01061.24 RLN84616.1 - 4.3e-29 101.4 28.7 4.9e-29 101.2 21.8 3.1 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 RLN84616.1 - 6.2e-17 62.4 0.0 1.1e-16 61.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN84616.1 - 1.3e-05 25.2 0.0 0.049 13.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system PDR_CDR PF06422.12 RLN84616.1 - 0.00013 21.8 0.0 0.01 15.7 0.0 2.6 2 0 0 2 2 2 1 CDR ABC transporter RsgA_GTPase PF03193.16 RLN84616.1 - 0.00033 20.6 0.3 0.002 18.1 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 RLN84616.1 - 0.004 16.9 0.7 0.0094 15.7 0.7 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN84616.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RLN84616.1 - 0.018 15.5 0.1 0.039 14.3 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF2399 PF09664.10 RLN84616.1 - 0.14 12.0 0.1 0.33 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) AAA_23 PF13476.6 RLN84616.1 - 0.15 12.5 0.4 0.74 10.3 0.3 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 RLN84616.1 - 0.17 12.1 0.1 0.37 11.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 RLN84616.1 - 0.18 11.4 0.2 0.31 10.6 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AMP-binding PF00501.28 RLN84619.1 - 3.6e-78 263.0 0.0 4.5e-78 262.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cas_Cas2CT1978 PF09707.10 RLN84619.1 - 1.4e-05 25.1 0.0 0.00033 20.6 0.0 3.1 5 0 0 5 5 5 1 CRISPR-associated protein (Cas_Cas2CT1978) Ank_4 PF13637.6 RLN84621.1 - 1.4e-12 47.9 0.3 6.7e-08 32.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN84621.1 - 8.9e-11 41.8 0.8 1.3e-10 41.3 0.4 1.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN84621.1 - 6.9e-06 26.0 0.4 0.00041 20.6 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 RLN84621.1 - 8.9e-06 26.2 0.1 1.2e-05 25.8 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 RLN84621.1 - 0.0032 17.8 0.5 0.43 11.1 0.2 2.3 2 0 0 2 2 2 1 Ankyrin repeat zf-RING_2 PF13639.6 RLN84622.1 - 1.4e-08 34.9 13.8 5.6e-08 33.0 9.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 RLN84622.1 - 2.4e-07 30.9 4.6 2.4e-07 30.9 4.6 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RLN84622.1 - 4.5e-06 26.5 9.1 4.5e-06 26.5 9.1 2.4 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 RLN84622.1 - 9.3e-05 22.1 4.1 9.3e-05 22.1 4.1 2.3 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RLN84622.1 - 9.8e-05 22.1 11.5 9.8e-05 22.1 11.5 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN84622.1 - 0.00027 20.7 11.2 0.00027 20.7 11.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RLN84622.1 - 0.00028 20.9 3.0 0.00028 20.9 3.0 1.6 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 RLN84622.1 - 0.00049 20.1 8.8 0.00049 20.1 8.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zinc_ribbon_15 PF17032.5 RLN84622.1 - 0.0067 17.1 3.4 0.15 12.8 0.0 2.4 2 0 0 2 2 2 1 zinc-ribbon family Prok-RING_4 PF14447.6 RLN84622.1 - 0.0083 16.0 6.8 0.0083 16.0 6.8 2.6 2 2 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 RLN84622.1 - 0.0095 15.5 6.9 0.0095 15.5 6.9 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 RLN84622.1 - 0.014 15.2 7.3 0.014 15.2 7.3 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.10 RLN84622.1 - 0.46 10.6 11.4 0.56 10.4 1.5 3.3 3 1 0 3 3 3 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 RLN84622.1 - 1.3 8.6 6.3 14 5.3 0.1 3.4 4 0 0 4 4 4 0 TFIIB zinc-binding PHD PF00628.29 RLN84622.1 - 1.3 8.9 19.1 0.9 9.5 9.9 2.7 2 1 0 2 2 2 0 PHD-finger Elf1 PF05129.13 RLN84622.1 - 4.3 7.5 8.8 8.3 6.5 0.0 3.8 3 1 1 4 4 4 0 Transcription elongation factor Elf1 like P_C10 PF14974.6 RLN84624.1 - 0.17 12.0 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein C10 PDEase_I PF00233.19 RLN84698.1 - 1e-18 68.0 0.0 2e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Dimer_Tnp_hAT PF05699.14 RLN84698.1 - 1.6e-10 40.6 2.2 1.9e-10 40.4 0.1 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region PIN_8 PF18476.1 RLN84699.1 - 9.2 6.0 10.3 8.8 6.1 5.7 2.2 1 1 1 2 2 2 0 PIN like domain Mod_r PF07200.13 RLN84701.1 - 2.3e-17 63.5 0.3 2.8e-11 43.7 0.0 2.2 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein Ion_trans PF00520.31 RLN84702.1 - 5.3e-43 147.0 12.4 1.1e-24 87.1 3.2 2.5 2 0 0 2 2 2 2 Ion transport protein cNMP_binding PF00027.29 RLN84702.1 - 6.1e-19 67.9 0.1 1.5e-12 47.4 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 RLN84702.1 - 2e-18 66.1 12.1 8.2e-09 35.3 2.7 3.0 2 0 0 2 2 2 2 Ion channel PhoLip_ATPase_C PF16212.5 RLN84703.1 - 1.6e-55 188.6 12.3 1.6e-55 188.6 12.3 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RLN84703.1 - 2.1e-19 69.0 0.8 4.7e-19 67.8 0.8 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RLN84703.1 - 2.7e-12 47.4 1.5 7e-07 29.7 0.4 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN84703.1 - 5.6e-08 32.8 0.0 1.6e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RLN84703.1 - 7e-07 28.9 0.0 4.3e-06 26.4 0.0 2.2 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RLN84703.1 - 0.0037 17.0 0.0 0.0083 15.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 RLN84703.1 - 0.021 15.2 0.0 8.1 6.8 0.0 2.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 RLN84703.1 - 0.035 14.2 0.0 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Med12-LCEWAV PF12145.8 RLN84704.1 - 1.4e-05 24.2 0.0 4.6e-05 22.5 0.0 1.7 1 1 1 2 2 2 1 Eukaryotic Mediator 12 subunit domain TFIID-18kDa PF02269.16 RLN84706.1 - 6.2e-05 23.0 0.0 9.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIIF_alpha PF05793.12 RLN84706.1 - 0.0081 14.8 1.5 0.0087 14.7 1.5 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) EF-hand_6 PF13405.6 RLN84707.1 - 2.8e-08 33.0 0.4 0.0009 19.0 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RLN84707.1 - 3.6e-08 32.4 2.8 1.5e-05 24.2 0.3 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RLN84707.1 - 0.00015 22.2 0.3 0.00029 21.2 0.3 1.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RLN84707.1 - 0.0021 17.9 2.9 0.0059 16.4 0.5 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN84707.1 - 0.012 15.1 2.3 1.4 8.5 0.1 2.4 2 0 0 2 2 2 0 EF hand ASF1_hist_chap PF04729.13 RLN84708.1 - 3.9e-57 192.5 0.0 6.1e-57 191.9 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone Ribosomal_L24e PF01246.20 RLN84710.1 - 8.1e-26 90.0 1.1 8.1e-26 90.0 1.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e Methyltransf_25 PF13649.6 RLN84711.1 - 5.7e-13 49.4 0.0 1.7e-12 47.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RLN84711.1 - 4.9e-11 42.6 0.0 6.7e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 RLN84711.1 - 3.5e-10 39.9 0.0 7.1e-10 38.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN84711.1 - 7.8e-10 39.3 0.0 2.6e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 RLN84711.1 - 1e-06 28.0 0.1 1.4e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 RLN84711.1 - 1.3e-06 28.4 0.0 3.9e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 RLN84711.1 - 1.5e-06 27.7 0.0 2.1e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 RLN84711.1 - 6.3e-06 26.2 0.1 1.2e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN84711.1 - 1.5e-05 25.7 0.0 2.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN84711.1 - 4.7e-05 23.0 0.1 7.3e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 RLN84711.1 - 0.0006 19.2 0.0 0.00092 18.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 RLN84711.1 - 0.0016 18.6 0.4 0.0076 16.4 0.4 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 RLN84711.1 - 0.0039 17.2 0.0 0.006 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 RLN84711.1 - 0.0073 16.1 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 RLN84711.1 - 0.023 14.4 0.1 0.035 13.9 0.1 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PRMT5 PF05185.16 RLN84711.1 - 0.039 13.8 0.1 0.082 12.7 0.1 1.5 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_24 PF13578.6 RLN84711.1 - 0.046 14.7 0.0 0.079 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 RLN84711.1 - 0.064 12.5 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Met_10 PF02475.16 RLN84711.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Cons_hypoth95 PF03602.15 RLN84711.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ion_trans PF00520.31 RLN84713.1 - 3e-16 59.4 9.7 1.1e-14 54.3 9.7 2.1 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RLN84713.1 - 8.2e-13 48.1 6.2 8.2e-13 48.1 6.2 2.4 2 0 0 2 2 2 2 Ion channel Flavi_NS4A PF01350.17 RLN84713.1 - 0.07 13.1 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A Aminotran_1_2 PF00155.21 RLN84714.1 - 8.6e-26 90.9 0.0 1e-25 90.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 RLN84714.1 - 9.7e-11 41.1 0.0 1.2e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Mito_carr PF00153.27 RLN84715.1 - 2.1e-37 127.0 2.4 3.2e-18 65.4 0.2 2.3 2 1 0 2 2 2 2 Mitochondrial carrier protein Serine_protease PF18405.1 RLN84715.1 - 1.1 8.4 4.9 0.83 8.8 0.3 2.1 1 1 1 2 2 2 0 Gammaproteobacterial serine protease CBFB_NFYA PF02045.15 RLN84716.1 - 6.2e-27 94.0 8.1 6.2e-27 94.0 8.1 1.9 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DivIC PF04977.15 RLN84716.1 - 0.014 15.1 2.1 0.14 11.9 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator SNAP PF14938.6 RLN84719.1 - 2.3e-15 56.8 6.6 3.4e-15 56.2 6.6 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_1 PF00515.28 RLN84720.1 - 1.5e-53 176.5 16.7 0.0033 17.2 0.2 21.8 22 0 0 22 22 22 13 Tetratricopeptide repeat TPR_2 PF07719.17 RLN84720.1 - 3e-45 148.7 46.6 0.0054 16.7 0.0 21.2 22 0 0 22 22 21 13 Tetratricopeptide repeat TPR_11 PF13414.6 RLN84720.1 - 2.2e-36 123.2 10.6 0.00036 20.2 0.1 16.2 11 5 5 16 16 16 8 TPR repeat TPR_17 PF13431.6 RLN84720.1 - 2.6e-27 93.2 21.5 0.0026 18.0 0.1 18.7 19 0 0 19 19 19 3 Tetratricopeptide repeat TPR_9 PF13371.6 RLN84720.1 - 1.1e-26 92.7 80.4 5.8e-05 23.2 6.1 15.2 9 5 5 15 15 15 10 Tetratricopeptide repeat TPR_16 PF13432.6 RLN84720.1 - 2.2e-25 89.0 76.4 0.00017 22.2 3.8 15.3 11 6 4 16 16 15 8 Tetratricopeptide repeat TPR_8 PF13181.6 RLN84720.1 - 1.5e-23 81.0 14.4 0.25 11.7 0.0 16.4 18 2 1 19 19 16 4 Tetratricopeptide repeat TPR_19 PF14559.6 RLN84720.1 - 3.2e-22 78.8 41.8 0.00063 20.2 0.2 12.1 9 4 4 14 14 14 7 Tetratricopeptide repeat TPR_14 PF13428.6 RLN84720.1 - 1.3e-21 75.5 60.6 0.00021 21.8 0.4 16.3 11 4 7 18 18 17 7 Tetratricopeptide repeat TPR_12 PF13424.6 RLN84720.1 - 6.1e-16 58.5 58.0 0.0082 16.4 0.6 13.7 10 3 6 16 16 15 10 Tetratricopeptide repeat TPR_7 PF13176.6 RLN84720.1 - 1.7e-06 27.6 41.8 1.3 9.2 0.1 14.3 18 1 1 19 19 17 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN84720.1 - 7.9e-06 26.0 26.1 0.15 12.3 0.2 8.4 7 2 2 9 9 9 3 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 RLN84720.1 - 3.5e-05 22.9 1.2 6.6 5.5 0.0 5.7 6 0 0 6 6 6 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 RLN84720.1 - 0.00014 21.2 18.3 0.095 11.9 0.1 6.4 6 2 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 RLN84720.1 - 0.0006 20.3 35.6 0.059 14.0 0.1 12.8 16 0 0 16 16 13 1 Tetratricopeptide repeat TPR_20 PF14561.6 RLN84720.1 - 0.023 15.0 15.1 4.1 7.8 0.8 6.4 6 1 0 6 6 6 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 RLN84720.1 - 0.15 11.5 16.1 0.45 10.0 0.0 6.6 7 0 0 7 7 7 0 SHNi-TPR Fis1_TPR_C PF14853.6 RLN84720.1 - 0.51 10.4 6.3 12 6.1 0.1 4.3 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat Aldedh PF00171.22 RLN84721.1 - 9.8e-102 340.8 1.5 1.4e-101 340.4 1.5 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_C48 PF02902.19 RLN84792.1 - 4.9e-08 33.1 0.0 1.2e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SWIM PF04434.17 RLN84792.1 - 0.026 14.2 0.1 0.026 14.2 0.1 1.8 2 0 0 2 2 2 0 SWIM zinc finger Peptidase_C5 PF00770.18 RLN84792.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 Adenovirus endoprotease EF-hand_1 PF00036.32 RLN84794.1 - 1.3e-13 49.4 0.8 1.1e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RLN84794.1 - 3.7e-13 49.1 0.5 1.7e-10 40.6 0.1 1.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 RLN84794.1 - 5.1e-13 49.3 0.5 2.1e-12 47.3 0.5 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN84794.1 - 3.6e-11 42.0 1.7 1e-05 24.8 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN84794.1 - 3.8e-11 42.0 2.0 5.8e-06 25.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_11 PF08976.11 RLN84794.1 - 1.4e-05 25.9 0.2 1.6e-05 25.7 0.2 1.1 1 0 0 1 1 1 1 EF-hand domain Caleosin PF05042.13 RLN84794.1 - 0.0034 17.3 0.2 0.049 13.6 0.0 2.0 2 0 0 2 2 2 1 Caleosin related protein EF-hand_4 PF12763.7 RLN84794.1 - 0.017 15.0 0.2 0.021 14.7 0.2 1.3 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DUF5580 PF17743.1 RLN84794.1 - 0.041 12.4 0.0 0.047 12.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) PH PF00169.29 RLN84795.1 - 0.14 12.7 0.0 19 5.8 0.0 2.4 2 0 0 2 2 2 0 PH domain PX PF00787.24 RLN84796.1 - 0.00022 21.2 0.0 0.00025 21.0 0.0 1.1 1 0 0 1 1 1 1 PX domain Myb_DNA-binding PF00249.31 RLN84797.1 - 0.0025 18.0 0.1 0.0044 17.2 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN84797.1 - 0.03 14.6 0.0 0.048 13.9 0.0 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 RLN84797.1 - 0.14 12.4 0.2 0.2 11.9 0.2 1.2 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Glyco_trans_4_2 PF13477.6 RLN84798.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like TMEM208_SND2 PF05620.11 RLN84799.1 - 6.2e-23 81.4 0.6 2.1e-20 73.2 0.6 2.0 1 1 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 MIOX PF05153.15 RLN84799.1 - 0.052 13.1 0.1 0.071 12.7 0.1 1.2 1 0 0 1 1 1 0 Myo-inositol oxygenase HAT_KAT11 PF08214.11 RLN84800.1 - 7.3e-16 58.4 0.0 1.2e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein Bromodomain PF00439.25 RLN84800.1 - 7.3e-14 51.6 0.0 1.4e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Bromodomain RGS PF00615.19 RLN84800.1 - 5.2e-10 39.6 0.0 1e-06 29.0 0.0 2.7 2 0 0 2 2 2 2 Regulator of G protein signaling domain ZZ PF00569.17 RLN84800.1 - 0.0084 15.9 3.5 0.0084 15.9 3.5 2.2 2 0 0 2 2 2 1 Zinc finger, ZZ type TruB_C PF09142.11 RLN84800.1 - 0.061 13.1 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal Ank_2 PF12796.7 RLN84801.1 - 8.7e-100 327.5 16.6 8.1e-18 64.8 0.4 7.9 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN84801.1 - 7.4e-89 291.1 0.9 6.9e-10 39.3 0.0 10.8 5 3 6 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN84801.1 - 1.8e-79 260.7 45.0 3.9e-07 30.2 0.1 13.8 2 1 14 16 16 16 15 Ankyrin repeats (many copies) Ank PF00023.30 RLN84801.1 - 2.1e-70 230.3 25.1 0.00012 22.3 0.0 15.2 15 0 0 15 15 15 13 Ankyrin repeat Ank_3 PF13606.6 RLN84801.1 - 2.4e-63 202.6 3.8 0.0025 18.2 0.0 16.6 17 0 0 17 17 17 15 Ankyrin repeat Ribosomal_L21e PF01157.18 RLN84801.1 - 0.013 15.3 0.0 20 5.1 0.0 4.7 6 0 0 6 6 6 0 Ribosomal protein L21e DUF1331 PF07048.11 RLN84801.1 - 0.23 11.1 0.8 1.8e+02 1.9 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1331) PheRS_DBD1 PF18552.1 RLN84801.1 - 0.52 10.1 8.4 1.4e+02 2.3 0.0 6.8 7 0 0 7 7 7 0 PheRS DNA binding domain 1 PK_C PF02887.16 RLN84801.1 - 0.78 10.0 9.1 1.9e+02 2.3 0.0 6.6 6 1 0 6 6 6 0 Pyruvate kinase, alpha/beta domain DUF659 PF04937.15 RLN84802.1 - 6e-10 39.2 0.0 9.6e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SR1P PF13790.6 RLN84802.1 - 0.029 14.5 0.2 0.088 12.9 0.2 1.8 1 0 0 1 1 1 0 SR1 protein Phytochelatin PF05023.14 RLN84804.1 - 1.8e-39 135.2 0.0 2.4e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Phytochelatin synthase PP2C PF00481.21 RLN84883.1 - 9.4e-55 186.0 0.0 3.6e-54 184.1 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RLN84883.1 - 3.4e-06 26.9 0.0 7.8e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C IQ PF00612.27 RLN84885.1 - 0.00042 19.8 0.4 0.00097 18.7 0.4 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif NOA36 PF06524.12 RLN84885.1 - 2.7 7.2 11.0 4.8 6.4 11.0 1.3 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 RLN84885.1 - 3.8 6.8 10.2 6.6 6.1 10.2 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RLN84885.1 - 4.5 5.4 10.5 6.7 4.8 10.5 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2052 PF09747.9 RLN84886.1 - 6.6e-33 114.5 22.3 1.7e-32 113.2 22.3 1.7 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Afi1 PF07792.12 RLN84886.1 - 3.1 8.3 6.5 9.5 6.7 6.5 2.0 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Glutaredoxin PF00462.24 RLN84887.1 - 9.7e-21 73.8 0.0 1.8e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin SH3BGR PF04908.15 RLN84887.1 - 0.023 14.9 0.0 0.067 13.3 0.0 1.7 1 1 0 1 1 1 0 SH3-binding, glutamic acid-rich protein GREB1 PF15782.5 RLN84887.1 - 0.029 11.5 0.0 0.032 11.4 0.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SAC3_GANP PF03399.16 RLN84888.1 - 1.3e-19 70.7 1.4 7.4e-18 64.9 1.2 2.2 1 1 0 1 1 1 1 SAC3/GANP family Chorismate_synt PF01264.21 RLN84889.1 - 4.8e-95 318.0 0.0 7.1e-95 317.5 0.0 1.2 1 0 0 1 1 1 1 Chorismate synthase adh_short_C2 PF13561.6 RLN84890.1 - 5.8e-36 124.2 0.4 4.2e-29 101.8 0.1 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RLN84890.1 - 3.4e-28 98.5 0.0 3.6e-27 95.1 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.10 RLN84890.1 - 0.033 13.6 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) FeS PF04060.13 RLN84890.1 - 0.2 11.4 0.2 0.45 10.2 0.2 1.7 1 0 0 1 1 1 0 Putative Fe-S cluster adh_short_C2 PF13561.6 RLN84891.1 - 1.1e-40 139.6 0.2 2.4e-40 138.5 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RLN84891.1 - 5.4e-40 136.9 0.9 9.9e-39 132.8 0.9 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RLN84891.1 - 0.0019 18.2 0.5 0.036 14.0 0.5 2.2 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 RLN84891.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PH PF00169.29 RLN84892.1 - 2e-27 95.7 0.0 1.4e-10 41.6 0.0 5.7 5 0 0 5 5 5 4 PH domain PH_11 PF15413.6 RLN84892.1 - 2e-05 24.9 0.1 6.8 7.2 0.0 5.5 5 2 0 5 5 5 2 Pleckstrin homology domain PH_9 PF15410.6 RLN84892.1 - 0.0049 17.2 0.0 2.3 8.6 0.0 3.9 3 1 0 3 3 3 1 Pleckstrin homology domain NHase_beta PF02211.15 RLN84892.1 - 0.88 9.6 4.0 2.4 8.1 4.0 1.7 1 0 0 1 1 1 0 Nitrile hydratase beta subunit YabA PF06156.13 RLN84892.1 - 5.7 7.6 7.8 0.48 11.1 0.4 2.6 2 0 0 2 2 2 0 Initiation control protein YabA GDP_Man_Dehyd PF16363.5 RLN84894.1 - 5.8e-61 206.7 0.0 3.7e-60 204.1 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RLN84894.1 - 1.1e-54 185.5 0.0 1.3e-54 185.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 RLN84894.1 - 2.1e-22 79.5 0.0 2.5e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 RLN84894.1 - 1.6e-20 73.4 0.0 1.4e-19 70.3 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 RLN84894.1 - 5.1e-14 52.0 0.0 8.6e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 RLN84894.1 - 1.6e-08 34.1 0.0 3.3e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 RLN84894.1 - 7.8e-07 29.2 0.0 2.9e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 RLN84894.1 - 9.8e-06 25.2 0.0 4.5e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 RLN84894.1 - 7.1e-05 22.8 0.1 0.00036 20.5 0.1 2.0 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 RLN84894.1 - 0.017 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family NIF PF03031.18 RLN84896.1 - 1.4e-17 63.9 0.0 2.7e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase CTC1 PF15489.6 RLN84973.1 - 0.091 10.3 0.0 0.13 9.7 0.0 1.1 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 UPF0061 PF02696.14 RLN84974.1 - 1.8e-119 399.6 0.0 6.5e-119 397.8 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Ank_2 PF12796.7 RLN84974.1 - 1.7e-21 76.6 1.8 2.1e-07 31.4 0.2 4.8 2 1 4 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN84974.1 - 1.8e-19 69.8 7.9 2.3e-06 28.0 0.5 6.9 5 1 2 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN84974.1 - 8.4e-13 48.3 5.7 0.12 12.7 0.0 6.3 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN84974.1 - 7.3e-09 35.2 0.2 1.3 9.8 0.0 7.0 7 1 1 8 8 8 2 Ankyrin repeat RRM_1 PF00076.22 RLN84975.1 - 1.2e-12 47.5 0.0 8.4e-12 44.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hnRNP_Q_AcD PF18360.1 RLN84975.1 - 9.8e-12 44.7 0.1 1.9e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain RIBIOP_C PF04950.12 RLN84976.1 - 3.8e-88 295.7 0.0 3.8e-88 295.7 0.0 2.3 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 RLN84976.1 - 3.3e-28 97.6 0.2 1.4e-27 95.6 0.0 2.3 2 0 0 2 2 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 RLN84976.1 - 2.7e-05 24.5 0.0 0.00011 22.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 RLN84976.1 - 0.00015 22.2 0.3 0.00048 20.5 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA PF00004.29 RLN84976.1 - 0.00036 21.0 0.0 0.0012 19.3 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 RLN84976.1 - 0.0014 18.2 0.0 0.12 11.8 0.0 2.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 RLN84976.1 - 0.0035 17.5 0.0 0.0035 17.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 RLN84976.1 - 0.0048 17.5 0.0 0.0048 17.5 0.0 3.8 3 1 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 RLN84976.1 - 0.011 15.8 0.1 0.067 13.3 0.1 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 RLN84976.1 - 0.013 15.2 0.1 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.9 RLN84976.1 - 0.019 14.7 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 RLN84976.1 - 0.022 15.1 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 RLN84976.1 - 0.045 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 RLN84976.1 - 0.047 14.2 2.8 0.061 13.8 0.0 2.6 3 0 0 3 3 2 0 ABC transporter NTPase_1 PF03266.15 RLN84976.1 - 0.053 13.4 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.22 RLN84976.1 - 0.062 13.7 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 RLN84976.1 - 0.068 12.7 0.2 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 RLN84976.1 - 0.083 12.8 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 RLN84976.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein cNMP_binding PF00027.29 RLN84977.1 - 2.2e-24 85.3 0.2 2.4e-10 40.3 0.1 4.7 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain RGS PF00615.19 RLN84977.1 - 7.4e-10 39.1 0.1 1.5e-09 38.1 0.1 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain Ufd2P_core PF10408.9 RLN84978.1 - 1.6e-170 568.8 0.1 3.2e-170 567.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin elongating factor core DUF1768 PF08719.11 RLN84978.1 - 9.2e-37 126.8 0.0 1.9e-36 125.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) U-box PF04564.15 RLN84978.1 - 4.5e-29 100.4 0.2 1.3e-28 98.9 0.2 1.8 1 0 0 1 1 1 1 U-box domain GUCT PF08152.12 RLN84978.1 - 0.17 12.2 0.5 5.8 7.3 0.2 2.7 2 0 0 2 2 2 0 GUCT (NUC152) domain Herpes_UL32 PF06070.11 RLN84978.1 - 0.25 9.1 2.8 0.39 8.4 2.8 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Med9 PF07544.13 RLN84978.1 - 1.2 9.3 3.9 0.69 10.1 0.1 2.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 WW PF00397.26 RLN84980.1 - 2.1e-24 85.3 6.1 3.7e-08 33.3 0.2 3.5 3 0 0 3 3 3 3 WW domain IQ PF00612.27 RLN84980.1 - 0.43 10.5 4.1 1.1 9.3 4.1 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Pkinase_Tyr PF07714.17 RLN84981.1 - 7.6e-10 38.5 0.0 6.8e-09 35.4 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN84981.1 - 3.4e-08 33.2 0.0 1.5e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain SPG48 PF14764.6 RLN84981.1 - 0.28 11.7 2.4 0.77 10.2 1.0 2.5 2 0 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking SF1-HH PF16275.5 RLN84984.1 - 1.5e-30 105.8 2.2 5e-30 104.1 2.2 1.9 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 RLN84984.1 - 8.7e-09 35.1 0.7 1.9e-08 34.0 0.7 1.6 1 0 0 1 1 1 1 KH domain PHD_4 PF16866.5 RLN84984.1 - 0.0009 19.3 2.9 0.002 18.2 2.9 1.6 1 0 0 1 1 1 1 PHD-finger DGF-1_C PF11040.8 RLN84984.1 - 0.061 13.3 0.0 0.48 10.5 0.0 2.6 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus zf-CCHC PF00098.23 RLN84984.1 - 0.098 12.8 11.8 0.059 13.5 4.9 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 RLN84984.1 - 0.87 9.5 12.4 0.072 12.9 6.9 2.1 2 0 0 2 2 2 0 Zinc knuckle DUF4407 PF14362.6 RLN84984.1 - 8.1 5.7 5.8 2.9 7.2 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Mad3_BUB1_I PF08311.12 RLN84985.1 - 5.8e-34 116.8 1.8 1.1e-32 112.6 1.8 2.3 1 1 0 1 1 1 1 Mad3/BUB1 homology region 1 DUF4614 PF15391.6 RLN84985.1 - 0.076 13.0 0.0 0.076 13.0 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4614) HEAT PF02985.22 RLN84986.1 - 0.0071 16.5 2.1 33 5.1 0.0 4.8 4 0 0 4 4 4 3 HEAT repeat DHDPS PF00701.22 RLN84987.1 - 5.3e-86 287.9 0.3 6e-86 287.7 0.3 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.6 RLN84987.1 - 0.016 14.7 0.1 0.025 14.0 0.1 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Trp_syntA PF00290.20 RLN84987.1 - 0.032 13.1 0.2 0.1 11.4 0.1 1.9 1 1 1 2 2 2 0 Tryptophan synthase alpha chain Pribosyltran_N PF13793.6 RLN84987.1 - 0.039 13.9 0.0 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of ribose phosphate pyrophosphokinase PA PF02225.22 RLN84987.1 - 0.087 12.9 0.9 0.8 9.8 0.4 2.4 2 0 0 2 2 2 0 PA domain Amidohydro_2 PF04909.14 RLN84987.1 - 0.2 11.4 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase LapA_dom PF06305.11 RLN84988.1 - 0.2 11.5 0.4 0.39 10.6 0.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4083 PF13314.6 RLN84988.1 - 0.21 11.6 0.2 0.51 10.3 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) HSF_DNA-bind PF00447.17 RLN84989.1 - 1.7e-24 86.2 0.8 3.5e-24 85.2 0.8 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding TEX13 PF15186.6 RLN84989.1 - 0.04 13.6 1.3 0.073 12.8 1.3 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Nsp1_C PF05064.13 RLN84989.1 - 0.13 12.1 2.2 0.31 10.8 2.2 1.6 1 0 0 1 1 1 0 Nsp1-like C-terminal region MULE PF10551.9 RLN84990.1 - 1.3e-06 28.7 0.0 1.6e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 MULE transposase domain GST_N_3 PF13417.6 RLN84991.1 - 2.4e-16 59.9 0.0 5.2e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN84991.1 - 6.2e-14 52.1 0.0 2.2e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RLN84991.1 - 7.1e-13 48.7 0.0 1.3e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RLN84991.1 - 1.3e-05 25.3 0.0 1.9e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RLN84991.1 - 0.00014 21.9 0.0 0.00033 20.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RLN84991.1 - 0.0013 18.9 0.0 0.0025 18.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tht1 PF04163.12 RLN84991.1 - 0.014 14.2 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein Tom37 PF10568.9 RLN84991.1 - 0.027 14.8 0.0 0.058 13.7 0.0 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Avl9 PF09794.9 RLN84993.1 - 0.00083 18.2 0.0 0.001 17.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 Afi1 PF07792.12 RLN84993.1 - 0.052 14.0 0.0 0.078 13.5 0.0 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking tRNA-synt_2 PF00152.20 RLN84994.1 - 1.2e-57 195.4 0.0 2.1e-57 194.6 0.0 1.3 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RLN84994.1 - 1.4e-08 34.6 0.0 3.4e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 RLN84994.1 - 0.00018 21.1 0.1 0.026 14.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) MtN3_slv PF03083.16 RLN84995.1 - 1.2e-07 31.7 0.6 1.2e-07 31.7 0.6 1.8 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange Cytochrom_B_C PF00032.17 RLN84995.1 - 0.006 16.8 3.2 1.1 9.6 0.4 2.1 1 1 1 2 2 2 2 Cytochrome b(C-terminal)/b6/petD Nitrate_red_gam PF02665.14 RLN84995.1 - 0.012 15.1 1.7 0.014 14.9 1.0 1.3 1 1 0 1 1 1 0 Nitrate reductase gamma subunit DUF4149 PF13664.6 RLN84995.1 - 0.096 13.0 2.2 3.3 8.1 2.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) FUSC-like PF12805.7 RLN84995.1 - 0.21 10.7 0.8 0.32 10.0 0.8 1.3 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS MFS_1 PF07690.16 RLN84996.1 - 4.9e-11 42.1 41.1 2.5e-07 30.0 13.8 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RLN84996.1 - 6.6e-11 41.4 14.9 6.6e-11 41.4 14.9 2.3 2 0 0 2 2 2 1 MFS/sugar transport protein SpoV PF08183.11 RLN84996.1 - 0.013 15.5 0.8 4.2 7.4 0.1 2.6 2 0 0 2 2 2 0 Stage V sporulation protein family HCMV_UL124 PF17609.2 RLN84996.1 - 0.062 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function MFS_2 PF13347.6 RLN84997.1 - 4.9e-12 45.1 14.4 4.9e-12 45.1 14.4 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 RLN84997.1 - 1.5e-11 43.8 58.9 1.3e-10 40.7 29.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PRIMA1 PF16101.5 RLN84998.1 - 0.16 12.0 0.7 0.33 11.0 0.7 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 HEAT_2 PF13646.6 RLN84998.1 - 0.19 12.1 1.8 3.1 8.2 0.0 3.2 3 0 0 3 3 3 0 HEAT repeats DUF3549 PF12069.8 RLN84998.1 - 1.6 7.7 5.4 1.9 7.5 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3549) Ribonuclease_3 PF00636.26 RLN85000.1 - 5.9e-07 30.1 0.0 9.2e-05 23.0 0.0 2.9 2 0 0 2 2 2 1 Ribonuclease III domain COG4 PF08318.12 RLN85000.1 - 0.061 12.4 0.1 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 COG4 transport protein DUF1764 PF08576.10 RLN85000.1 - 3.2 8.7 5.5 4.6 8.2 3.4 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Ank_2 PF12796.7 RLN85001.1 - 3e-78 258.4 6.1 3.9e-12 46.6 0.1 7.5 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN85001.1 - 8.3e-59 188.6 12.8 0.00039 20.7 0.0 13.4 13 0 0 13 13 13 11 Ankyrin repeat Ank_4 PF13637.6 RLN85001.1 - 9.7e-56 185.5 9.4 2.2e-08 34.5 0.2 8.4 5 2 5 10 10 10 10 Ankyrin repeats (many copies) Ank PF00023.30 RLN85001.1 - 1.8e-55 183.1 26.6 3.1e-05 24.2 0.1 13.4 14 0 0 14 14 14 11 Ankyrin repeat Ank_5 PF13857.6 RLN85001.1 - 3.8e-55 183.2 28.8 1.8e-07 31.3 0.1 12.6 2 2 11 13 13 13 12 Ankyrin repeats (many copies) Methyltransf_15 PF09445.10 RLN85075.1 - 1.1e-34 119.4 0.0 1.4e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 RLN85075.1 - 2.4e-07 30.7 0.1 3.5e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 RLN85075.1 - 1.3e-06 28.2 0.2 1.3e-05 25.0 0.2 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 RLN85075.1 - 7.9e-06 25.6 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 RLN85075.1 - 5.5e-05 23.8 0.0 0.00014 22.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 RLN85075.1 - 9e-05 21.7 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.6 RLN85075.1 - 0.00032 20.5 0.0 0.00054 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN85075.1 - 0.00036 21.1 0.0 0.00099 19.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RLN85075.1 - 0.00041 19.8 0.1 0.00075 19.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 RLN85075.1 - 0.001 19.0 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 RLN85075.1 - 0.0012 18.1 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase MethyltransfD12 PF02086.15 RLN85075.1 - 0.0031 17.2 0.0 0.013 15.2 0.0 1.8 1 1 0 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase MTS PF05175.14 RLN85075.1 - 0.082 12.4 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain UQ_con PF00179.26 RLN85076.1 - 2.3e-23 82.4 0.1 2.6e-23 82.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Histone PF00125.24 RLN85077.1 - 1.5e-37 128.9 0.8 1.6e-37 128.8 0.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 RLN85077.1 - 0.00013 22.1 0.0 0.00015 21.8 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 RLN85077.1 - 0.00013 22.3 0.0 0.00016 21.9 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 RLN85077.1 - 0.029 14.4 0.0 0.031 14.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 RLN85077.1 - 0.053 13.8 0.0 0.067 13.5 0.0 1.1 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TPR_1 PF00515.28 RLN85078.1 - 9.3e-13 47.4 7.7 0.00048 19.8 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN85078.1 - 2.7e-12 45.8 10.3 5e-05 23.1 0.7 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN85078.1 - 2.8e-09 36.5 5.4 0.00079 19.1 0.9 2.9 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 RLN85078.1 - 1.1e-05 25.2 6.4 0.2 11.9 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN85078.1 - 0.001 19.3 5.4 0.0014 18.9 3.4 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN85078.1 - 0.0074 17.0 7.5 1.1 10.3 1.4 3.3 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN85078.1 - 0.015 15.5 2.9 0.071 13.3 2.9 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 RLN85078.1 - 0.05 14.0 1.5 4.4 7.9 0.1 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN85078.1 - 0.27 11.9 12.0 0.63 10.7 3.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN85078.1 - 3.4 7.6 7.4 0.57 10.1 0.6 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat MULE PF10551.9 RLN85079.1 - 0.0036 17.7 0.0 0.052 14.0 0.0 2.6 3 0 0 3 3 3 1 MULE transposase domain FSAP_sig_propep PF03032.15 RLN85080.1 - 0.062 13.3 2.9 0.14 12.2 2.9 1.5 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide DUF1818 PF08848.11 RLN85080.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1818) RF3_C PF16658.5 RLN85081.1 - 0.021 14.6 0.1 0.04 13.7 0.1 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain AAA_lid_4 PF17864.1 RLN85081.1 - 0.042 13.6 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 RuvB AAA lid domain CLIP1_ZNF PF16641.5 RLN85081.1 - 0.32 10.9 3.2 0.58 10.1 3.2 1.4 1 0 0 1 1 1 0 CLIP1 zinc knuckle PIP5K PF01504.18 RLN85082.1 - 1.1e-72 244.5 0.0 1.7e-71 240.7 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Frizzled PF01534.17 RLN85082.1 - 0.47 9.4 7.6 2.8 6.9 3.8 2.2 1 1 1 2 2 2 0 Frizzled/Smoothened family membrane region 7tm_2 PF00002.24 RLN85082.1 - 6.3 6.0 10.6 0.68 9.2 4.8 2.1 1 1 1 2 2 2 0 7 transmembrane receptor (Secretin family) COPIIcoated_ERV PF07970.12 RLN85083.1 - 2.1e-36 125.8 8.0 1.2e-19 71.1 0.3 2.6 2 1 1 3 3 3 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 RLN85083.1 - 3e-14 53.1 0.0 7.3e-14 51.9 0.0 1.7 1 1 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Kinesin PF00225.23 RLN85084.1 - 2.8e-85 286.2 1.9 5.5e-85 285.2 1.9 1.5 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN85084.1 - 1.3e-35 122.6 0.0 2.4e-35 121.7 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding CREPT PF16566.5 RLN85084.1 - 0.02 15.0 0.7 0.073 13.2 0.7 1.9 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour MCM3AP_GANP PF16769.5 RLN85084.1 - 0.31 9.3 5.3 0.45 8.7 5.3 1.2 1 0 0 1 1 1 0 MCM3AP domain of GANP TYA PF01021.19 RLN85084.1 - 0.36 11.2 2.5 0.7 10.2 0.1 2.6 2 0 0 2 2 2 0 TYA transposon protein FH2 PF02181.23 RLN85085.1 - 8.2e-78 262.1 1.3 1.3e-77 261.5 1.3 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain CCDC53 PF10152.9 RLN85085.1 - 1.1e-68 230.5 27.6 4.2e-12 46.7 0.1 8.2 9 0 0 9 9 9 6 Subunit CCDC53 of WASH complex PHD PF00628.29 RLN85085.1 - 0.0002 21.2 6.0 0.00058 19.7 6.0 1.9 1 1 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.6 RLN85085.1 - 0.0018 18.4 0.8 0.0045 17.1 0.8 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain DUF1664 PF07889.12 RLN85085.1 - 0.0034 17.4 0.1 1.3 9.1 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) zf-HC5HC2H PF13771.6 RLN85085.1 - 0.0063 16.7 0.4 0.019 15.2 0.4 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain DUF2318 PF10080.9 RLN85085.1 - 0.04 14.0 0.2 0.099 12.8 0.2 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Vps53_N PF04100.12 RLN85085.1 - 0.11 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Vps53-like, N-terminal PHD_4 PF16866.5 RLN85085.1 - 0.12 12.5 2.5 0.32 11.1 2.5 1.8 1 0 0 1 1 1 0 PHD-finger zf-PHD-like PF15446.6 RLN85085.1 - 0.24 11.0 8.9 0.04 13.5 2.8 2.7 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain zf-RING_2 PF13639.6 RLN85085.1 - 0.4 11.0 1.7 0.87 10.0 1.7 1.5 1 0 0 1 1 1 0 Ring finger domain Glyco_transf_28 PF03033.20 RLN85086.1 - 1.4e-28 99.6 0.6 2.3e-20 73.0 0.1 4.0 2 2 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 RLN85086.1 - 0.00012 21.0 0.0 0.00023 20.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 RLN85086.1 - 0.0007 19.9 0.0 0.0059 16.9 0.0 2.6 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 RLN85086.1 - 0.0013 18.6 0.3 0.0024 17.7 0.3 1.3 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal SIS_2 PF13580.6 RLN85086.1 - 0.045 13.8 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 SIS domain Glyco_transf_28 PF03033.20 RLN85087.1 - 1.4e-28 99.7 0.0 1.4e-18 67.3 0.1 3.4 2 2 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 RLN85087.1 - 2.4e-06 27.8 0.0 1.5e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain UDPGT PF00201.18 RLN85087.1 - 1.6e-05 24.0 0.1 3.1e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase VPS13_C PF16909.5 RLN85087.1 - 0.012 15.5 0.3 0.023 14.5 0.3 1.4 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Cas_CXXC_CXXC PF09706.10 RLN85087.1 - 0.049 13.9 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) Voltage_CLC PF00654.20 RLN85088.1 - 1.9e-65 221.5 22.4 1.9e-65 221.5 22.4 1.9 2 1 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 RLN85088.1 - 0.039 14.4 0.6 4 8.0 0.1 2.5 2 0 0 2 2 2 0 CBS domain Choline_kinase PF01633.20 RLN85089.1 - 1.2e-42 145.9 0.0 3.2e-42 144.5 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 RLN85089.1 - 5.3e-11 42.9 0.0 7.8e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4065 PF13274.6 RLN85091.1 - 0.088 13.7 0.1 0.14 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) NOA36 PF06524.12 RLN85091.1 - 0.45 9.8 4.7 0.57 9.5 4.7 1.2 1 0 0 1 1 1 0 NOA36 protein zf-CCCH PF00642.24 RLN85093.1 - 7.7e-20 70.3 20.6 1e-05 25.3 0.5 4.4 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 RLN85093.1 - 1.1e-16 61.4 21.2 1.6e-05 25.6 0.3 5.0 4 1 1 5 5 5 4 Torus domain zf_CCCH_4 PF18345.1 RLN85093.1 - 1.1e-15 57.1 33.2 5.2e-05 23.1 0.7 4.4 4 0 0 4 4 4 4 Zinc finger domain zf-CCCH_4 PF18044.1 RLN85093.1 - 6.7e-14 51.3 27.7 0.00071 19.3 0.5 4.5 4 0 0 4 4 4 4 CCCH-type zinc finger zf-B_box PF00643.24 RLN85093.1 - 3.2e-09 36.8 15.7 3.9e-07 30.1 4.3 2.5 2 0 0 2 2 2 2 B-box zinc finger R3H PF01424.22 RLN85093.1 - 3.4e-09 36.6 0.0 9.9e-09 35.1 0.0 1.8 1 0 0 1 1 1 1 R3H domain zf-CCCH_2 PF14608.6 RLN85093.1 - 5.8e-05 23.4 27.2 0.073 13.6 0.5 4.5 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 RLN85093.1 - 0.00073 19.7 9.6 0.049 13.9 0.0 4.3 4 0 0 4 4 4 2 Zinc-finger containing family zf-C2H2_jaz PF12171.8 RLN85093.1 - 0.31 11.4 6.4 1.1 9.7 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding C1_4 PF07975.12 RLN85093.1 - 1.7 8.9 14.7 1.6 9.0 1.6 3.4 2 1 0 2 2 2 0 TFIIH C1-like domain zf-ACC PF17848.1 RLN85093.1 - 2.9 8.1 11.0 21 5.3 0.0 4.3 3 1 1 4 4 4 0 Acetyl-coA carboxylase zinc finger domain Fer4 PF00037.27 RLN85094.1 - 7.8e-09 35.0 4.5 1.3e-08 34.3 4.5 1.4 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_7 PF12838.7 RLN85094.1 - 3.3e-07 30.8 0.1 4.3e-07 30.4 0.1 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 RLN85094.1 - 1.9e-05 25.5 0.1 3.4e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 RLN85094.1 - 0.0001 22.3 0.3 0.0002 21.4 0.1 1.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 RLN85094.1 - 0.00023 21.5 0.1 0.00042 20.7 0.1 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 RLN85094.1 - 0.0004 20.5 0.5 0.00079 19.5 0.2 1.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 RLN85094.1 - 0.00075 19.6 0.2 0.0014 18.7 0.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 RLN85094.1 - 0.001 19.1 2.0 0.002 18.1 2.0 1.5 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_17 PF13534.6 RLN85094.1 - 0.0046 17.5 0.2 0.0097 16.4 0.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 RLN85094.1 - 0.0055 16.7 4.5 0.011 15.8 4.5 1.5 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_18 PF13746.6 RLN85094.1 - 0.05 13.8 0.0 0.079 13.2 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 RLN85094.1 - 2.2 9.4 8.0 0.26 12.3 4.1 1.6 2 0 0 2 2 1 0 4Fe-4S binding domain TFIIIC_sub6 PF10419.9 RLN85095.1 - 4.6e-09 36.0 0.0 6.6e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain NAD_binding_10 PF13460.6 RLN85096.1 - 2.7e-13 50.2 0.0 2.9e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 RLN85096.1 - 3.8e-11 43.0 0.0 4.8e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 RLN85096.1 - 0.0014 18.6 0.0 0.0022 18.0 0.0 1.4 1 1 0 1 1 1 1 KR domain CRT10 PF08728.10 RLN85097.1 - 7.3 4.6 8.2 8.1 4.5 8.2 1.1 1 0 0 1 1 1 0 CRT10 JIP_LZII PF16471.5 RLN85175.1 - 3.5 7.9 5.5 0.75 10.0 1.4 2.1 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II Pyridoxal_deC PF00282.19 RLN85176.1 - 6.3e-80 268.7 0.0 9.7e-80 268.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF1977 PF09320.11 RLN85177.1 - 1.2e-23 83.4 1.0 2.9e-23 82.1 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 RLN85177.1 - 1.1e-09 38.3 1.7 0.00013 22.1 0.1 2.8 2 1 1 3 3 3 2 DnaJ domain TPR_2 PF07719.17 RLN85177.1 - 0.0013 18.7 0.0 0.0013 18.7 0.0 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN85177.1 - 0.015 15.1 0.0 0.041 13.7 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 RLN85177.1 - 0.079 13.2 0.1 2.1 8.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 RLN85177.1 - 0.13 12.4 0.0 0.46 10.6 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat LVIVD PF08309.11 RLN85180.1 - 0.023 14.0 0.1 0.07 12.5 0.1 1.8 1 0 0 1 1 1 0 LVIVD repeat Serglycin PF04360.12 RLN85180.1 - 0.8 9.6 13.1 0.06 13.3 0.6 3.3 3 0 0 3 3 3 0 Serglycin PhoLip_ATPase_C PF16212.5 RLN85181.1 - 8.9e-68 228.7 18.3 8.9e-68 228.7 18.3 1.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RLN85181.1 - 5.6e-16 58.0 2.8 1.8e-15 56.4 2.8 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Lactamase_B_2 PF12706.7 RLN85181.1 - 1.3e-12 47.6 1.9 3.4e-12 46.3 0.4 2.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Cation_ATPase PF13246.6 RLN85181.1 - 1.2e-11 44.5 0.0 1.3e-10 41.2 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Lactamase_B_4 PF13691.6 RLN85181.1 - 1.6e-10 40.5 0.1 1.3e-09 37.6 0.1 2.5 1 1 0 1 1 1 1 tRNase Z endonuclease Hydrolase PF00702.26 RLN85181.1 - 1.8e-07 31.7 4.3 0.00028 21.2 1.6 3.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RLN85181.1 - 5.7e-07 29.2 0.1 7.6e-06 25.6 0.0 2.9 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RLN85181.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Lactamase_B PF00753.27 RLN85181.1 - 0.043 13.8 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily SURF2 PF05477.11 RLN85182.1 - 8.7e-40 136.9 20.8 3.9e-39 134.7 20.8 1.7 1 1 0 1 1 1 1 Surfeit locus protein 2 (SURF2) BUD22 PF09073.10 RLN85182.1 - 0.3 10.4 24.6 0.38 10.0 24.6 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 RLN85182.1 - 0.71 8.0 29.1 0.81 7.8 29.1 1.0 1 0 0 1 1 1 0 Nop14-like family BATS PF06968.13 RLN85183.1 - 4.8e-18 65.1 0.2 4e-17 62.1 0.1 2.4 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 RLN85183.1 - 4.5e-14 53.2 0.9 7.4e-14 52.5 0.9 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Peptidase_M24 PF00557.24 RLN85183.1 - 0.059 13.0 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Metallopeptidase family M24 FAR1 PF03101.15 RLN85184.1 - 0.0039 17.9 0.0 0.0086 16.8 0.0 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain START PF01852.19 RLN85185.1 - 6e-23 81.3 0.1 7.4e-23 81.1 0.1 1.1 1 0 0 1 1 1 1 START domain DUF4097 PF13349.6 RLN85186.1 - 1.5e-05 24.5 0.0 0.0059 16.0 0.0 3.0 2 2 1 4 4 4 2 Putative adhesin Asparaginase_2 PF01112.18 RLN85187.1 - 1.7e-67 227.6 0.1 2.1e-67 227.4 0.1 1.0 1 0 0 1 1 1 1 Asparaginase PP2C PF00481.21 RLN85189.1 - 1.2e-53 182.3 2.4 9.7e-52 176.1 2.4 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RLN85189.1 - 1.3e-05 24.9 0.4 3.3e-05 23.6 0.4 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 RLN85189.1 - 0.0018 18.2 0.1 0.68 9.8 0.1 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) AcylCoA_dehyd_C PF12186.8 RLN85189.1 - 0.017 15.2 0.0 0.039 14.1 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal Hexapep PF00132.24 RLN85191.1 - 3.9e-14 51.7 10.5 3.5e-10 39.2 2.9 3.6 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 RLN85191.1 - 1.8e-11 44.1 0.1 3.8e-11 43.0 0.1 1.6 2 0 0 2 2 2 1 Maltose acetyltransferase Hexapep_2 PF14602.6 RLN85191.1 - 1e-10 41.2 14.1 5e-10 38.9 2.6 4.0 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase PDZ PF00595.24 RLN85192.1 - 0.0014 18.9 0.0 0.091 13.1 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 RLN85192.1 - 0.0055 16.5 0.0 0.93 9.4 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 RLN85192.1 - 0.021 15.1 0.0 0.35 11.2 0.0 2.3 2 0 0 2 2 2 0 PDZ domain Proteasome PF00227.26 RLN85193.1 - 1.8e-54 184.1 0.0 2.6e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RLN85193.1 - 7.4e-14 51.1 0.0 1.3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TACC_C PF05010.14 RLN85193.1 - 0.043 13.6 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PDZ_6 PF17820.1 RLN85194.1 - 0.00056 19.7 0.0 0.002 18.0 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 RLN85194.1 - 0.0025 18.1 0.0 0.012 16.0 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 RLN85194.1 - 0.094 13.0 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 PDZ domain NPL4 PF05021.15 RLN85195.1 - 0.009 15.4 0.0 0.01 15.2 0.0 1.0 1 0 0 1 1 1 1 NPL4 family PRK PF00485.18 RLN85196.1 - 3.8e-42 144.3 0.2 6.1e-42 143.6 0.2 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 RLN85196.1 - 1.9e-07 31.7 0.0 3e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RLN85196.1 - 3.9e-05 23.8 0.1 0.00013 22.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 RLN85196.1 - 0.0005 19.3 0.0 0.00095 18.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.6 RLN85196.1 - 0.0016 18.8 0.7 0.47 10.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 RLN85196.1 - 0.002 18.6 0.0 0.0033 17.9 0.0 1.6 1 1 0 1 1 1 1 ABC transporter CoaE PF01121.20 RLN85196.1 - 0.0025 17.5 2.8 0.27 10.9 0.1 2.4 2 0 0 2 2 2 2 Dephospho-CoA kinase Cytidylate_kin PF02224.18 RLN85196.1 - 0.018 14.8 2.9 0.8 9.4 0.0 2.6 2 1 1 3 3 3 0 Cytidylate kinase T2SSE PF00437.20 RLN85196.1 - 0.02 14.0 1.0 0.038 13.0 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein TsaE PF02367.17 RLN85196.1 - 0.022 14.8 0.0 0.076 13.0 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 RLN85196.1 - 0.032 14.1 0.3 0.15 12.0 0.0 2.3 4 0 0 4 4 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 RLN85196.1 - 0.049 13.9 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_8 PF12780.7 RLN85196.1 - 0.051 12.9 0.1 0.25 10.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 AAA PF00004.29 RLN85196.1 - 0.059 13.8 0.0 0.2 12.0 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN85196.1 - 0.065 13.6 0.0 0.14 12.5 0.0 1.6 2 0 0 2 2 1 0 AAA ATPase domain Roc PF08477.13 RLN85196.1 - 0.073 13.3 0.0 0.79 10.0 0.0 2.3 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 RLN85196.1 - 0.074 13.4 0.0 0.16 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RLN85196.1 - 0.076 13.3 0.0 0.19 11.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 RLN85196.1 - 0.077 12.6 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 RLN85196.1 - 0.087 12.1 0.0 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 RLN85196.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 RLN85196.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_26 PF13500.6 RLN85196.1 - 0.16 11.8 0.1 0.8 9.5 0.0 2.0 1 1 1 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 RLN85196.1 - 0.16 11.6 0.5 13 5.4 0.0 2.5 2 1 0 2 2 2 0 Thymidylate kinase AAA_29 PF13555.6 RLN85196.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RasGAP PF00616.19 RLN85197.1 - 1e-18 67.8 0.0 4.6e-13 49.4 0.0 3.4 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase START PF01852.19 RLN85197.1 - 3.9e-06 26.4 0.0 9.3e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 START domain Ost5 PF05251.12 RLN85198.1 - 0.14 12.4 1.7 0.23 11.8 1.7 1.3 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 Gemin6 PF06372.12 RLN85199.1 - 3.6e-11 42.9 0.0 4.6e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Gemin6 protein SM-ATX PF14438.6 RLN85199.1 - 7.5e-05 22.8 0.0 0.00012 22.1 0.0 1.4 1 1 0 1 1 1 1 Ataxin 2 SM domain Glyco_trans_2_3 PF13632.6 RLN85200.1 - 1.7e-15 57.5 7.3 5.5e-15 55.8 0.0 3.7 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.14 RLN85200.1 - 2.1e-11 43.1 4.2 2e-07 29.9 0.0 3.7 3 1 1 4 4 4 2 Cellulose synthase Glyco_tranf_2_3 PF13641.6 RLN85200.1 - 8.3e-09 35.7 0.0 8.3e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 PH PF00169.29 RLN85200.1 - 5.9e-08 33.2 0.2 1.5e-07 31.8 0.1 1.8 2 0 0 2 2 2 1 PH domain Glycos_transf_2 PF00535.26 RLN85200.1 - 5.1e-07 29.7 0.0 0.012 15.4 0.0 3.1 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 RLN85200.1 - 6.4e-06 25.8 0.0 0.00095 18.7 0.1 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 PH_11 PF15413.6 RLN85200.1 - 0.0018 18.7 0.2 0.0061 17.0 0.2 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 RLN85200.1 - 0.037 14.3 2.0 0.11 12.7 0.2 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain zf-C6H2 PF15801.5 RLN85200.1 - 1.9 8.8 18.9 0.046 14.0 10.9 2.2 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding RabGAP-TBC PF00566.18 RLN85201.1 - 2.2e-07 30.8 0.1 3.5e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain zf-Paramyx-P PF13008.7 RLN85201.1 - 0.11 12.0 2.5 0.32 10.5 2.5 1.8 1 0 0 1 1 1 0 Zinc-binding domain of Paramyxoviridae V protein PIG-U PF06728.13 RLN85276.1 - 2.4e-76 257.3 18.1 2.2e-68 231.1 5.9 2.0 1 1 1 2 2 2 2 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 RLN85276.1 - 0.81 9.3 12.3 1.3 8.7 12.3 1.3 1 0 0 1 1 1 0 8TM Microsporidial transmembrane domain Methyltransf_23 PF13489.6 RLN85277.1 - 4.4e-19 68.9 0.0 7.2e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Robl_LC7 PF03259.17 RLN85277.1 - 6.2e-15 54.7 0.0 1.1e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Roadblock/LC7 domain Methyltransf_25 PF13649.6 RLN85277.1 - 1.4e-13 51.3 0.1 3e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN85277.1 - 8.1e-13 48.8 0.0 1.9e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN85277.1 - 7.7e-10 38.5 0.0 1.3e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 RLN85277.1 - 4.7e-07 30.5 0.1 1.2e-06 29.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN85277.1 - 2.1e-06 27.6 0.0 3.6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain LAMTOR5 PF16672.5 RLN85277.1 - 0.027 14.4 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 STAS_2 PF13466.6 RLN85277.1 - 0.079 13.3 0.4 0.28 11.5 0.4 1.9 1 0 0 1 1 1 0 STAS domain MCM_bind PF09739.9 RLN85278.1 - 1.1e-97 327.9 0.0 5.7e-95 319.0 0.0 2.2 1 1 0 1 1 1 1 Mini-chromosome maintenance replisome factor GAPES3 PF17154.4 RLN85278.1 - 0.0033 17.4 0.1 0.0075 16.2 0.1 1.5 1 0 0 1 1 1 1 Gammaproteobacterial periplasmic sensor domain Pkinase PF00069.25 RLN85279.1 - 1.5e-59 201.5 0.1 2.2e-59 201.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain PP2C PF00481.21 RLN85279.1 - 2.3e-55 188.0 0.0 4.7e-55 187.0 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase_Tyr PF07714.17 RLN85279.1 - 4.5e-38 131.0 0.0 7.1e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN85279.1 - 9e-07 28.5 0.0 1.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RLN85279.1 - 0.00045 19.1 1.1 0.00075 18.4 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 RLN85279.1 - 0.021 14.4 0.7 0.044 13.4 0.7 1.5 1 0 0 1 1 1 0 RIO1 family Attacin_N PF03768.15 RLN85279.1 - 0.086 13.0 0.0 0.35 11.0 0.0 2.1 1 0 0 1 1 1 0 Attacin, N-terminal region Tautomerase PF01361.21 RLN85281.1 - 0.3 11.1 1.1 1.8 8.6 0.1 2.6 2 0 0 2 2 2 0 Tautomerase enzyme EGF_MSP1_1 PF12946.7 RLN85282.1 - 5.6 7.1 6.6 14 5.8 0.2 3.2 3 0 0 3 3 3 0 MSP1 EGF domain 1 WW PF00397.26 RLN85283.1 - 8.4e-05 22.6 0.1 0.00032 20.7 0.0 1.9 2 0 0 2 2 2 1 WW domain PCI PF01399.27 RLN85284.1 - 1.9e-13 50.8 0.0 4.8e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 PCI domain eIF3m_C_helix PF18005.1 RLN85284.1 - 0.0024 17.5 0.0 0.0089 15.7 0.0 2.0 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix NARG2_C PF10505.9 RLN85285.1 - 2.3e-09 37.1 0.0 4.2e-08 33.0 0.0 2.3 1 1 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus RNA_pol_Rpb1_5 PF04998.17 RLN85286.1 - 1.2e-31 110.1 0.1 1.4e-31 109.9 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RabGAP-TBC PF00566.18 RLN85287.1 - 1.5e-14 54.2 0.0 3.6e-14 52.9 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DSPc PF00782.20 RLN85287.1 - 1.5e-11 44.3 0.0 3.2e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 RLN85287.1 - 0.0098 15.9 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 RLN85287.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase YfiO PF13525.6 RLN85287.1 - 0.065 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein HTH_39 PF14090.6 RLN85287.1 - 0.25 11.1 1.8 22 4.9 1.5 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Glyco_trans_4_4 PF13579.6 RLN85287.1 - 0.8 10.1 0.0 0.8 10.1 0.0 3.0 4 0 0 4 4 4 0 Glycosyl transferase 4-like domain WW PF00397.26 RLN85290.1 - 1e-08 35.1 12.0 8.6e-07 28.9 4.1 2.6 2 0 0 2 2 2 2 WW domain IQ PF00612.27 RLN85290.1 - 0.00081 19.0 0.1 0.0029 17.2 0.1 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif CDC73_N PF16050.5 RLN85291.1 - 8.4e-16 58.1 3.2 4.6e-15 55.7 3.2 2.3 1 1 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal CDC73_C PF05179.14 RLN85291.1 - 2.7e-11 43.4 0.0 6.4e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Ion_trans PF00520.31 RLN85291.1 - 2.1e-06 27.2 2.3 3.9e-06 26.3 2.3 1.4 1 0 0 1 1 1 1 Ion transport protein BCIP PF13862.6 RLN85291.1 - 0.047 13.5 0.1 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 p21-C-terminal region-binding protein eIF3_subunit PF08597.10 RLN85291.1 - 1 9.2 8.1 3.5 7.5 8.1 1.9 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Malic_M PF03949.15 RLN85292.1 - 1.8e-98 328.9 0.1 2.3e-98 328.6 0.1 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 RLN85292.1 - 6.5e-69 231.4 0.0 2.7e-68 229.4 0.0 1.9 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Shikimate_DH PF01488.20 RLN85292.1 - 0.11 12.5 0.2 1.8 8.6 0.2 2.2 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF525 PF04379.14 RLN85293.1 - 4.4e-18 65.3 0.0 6.5e-17 61.6 0.0 2.5 2 1 0 2 2 2 1 ApaG domain Tox-HNH-EHHH PF15657.6 RLN85293.1 - 0.084 13.2 0.0 6.7 7.1 0.0 2.4 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxins ABC2_membrane PF01061.24 RLN85294.1 - 4.8e-67 225.4 65.1 2.7e-36 125.0 25.6 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN85294.1 - 1e-30 107.1 0.0 5.6e-14 52.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 RLN85294.1 - 5.7e-08 33.3 1.9 0.001 19.5 0.2 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 RLN85294.1 - 1.1e-06 28.7 0.0 0.31 10.8 0.0 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN85294.1 - 1.7e-06 27.7 3.8 0.008 15.9 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN85294.1 - 8.5e-06 25.8 0.4 0.088 12.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 RLN85294.1 - 2.2e-05 24.1 0.4 0.12 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RLN85294.1 - 0.0001 22.6 0.0 0.45 10.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN85294.1 - 0.0002 20.7 0.4 0.053 12.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin PDR_CDR PF06422.12 RLN85294.1 - 0.00077 19.3 2.3 0.0056 16.5 0.0 3.1 3 0 0 3 3 3 1 CDR ABC transporter AAA_23 PF13476.6 RLN85294.1 - 0.0038 17.8 0.4 1.4 9.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RLN85294.1 - 0.0053 17.3 0.0 3.5 8.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RLN85294.1 - 0.0057 17.1 0.0 3 8.3 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 RLN85294.1 - 0.0062 16.3 0.1 1.5 8.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 RLN85294.1 - 0.011 15.7 0.1 1.4 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 RLN85294.1 - 0.017 15.2 0.3 2 8.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 RLN85294.1 - 0.017 15.0 2.3 3.2 7.6 0.1 2.7 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 RLN85294.1 - 0.02 15.0 0.1 4 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 RLN85294.1 - 0.037 13.5 0.4 15 4.9 0.0 3.2 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 RLN85294.1 - 0.054 13.1 1.0 2.4 7.7 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 RLN85294.1 - 0.072 12.8 0.1 8.1 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 RLN85294.1 - 0.075 12.9 0.1 14 5.5 0.0 3.1 3 0 0 3 3 3 0 NTPase AAA_28 PF13521.6 RLN85294.1 - 0.089 13.0 0.1 12 6.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 RLN85294.1 - 0.19 11.8 1.1 9.6 6.2 0.2 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain FIST_C PF10442.9 RLN85296.1 - 0.014 15.3 0.1 0.026 14.5 0.1 1.4 1 1 0 1 1 1 0 FIST C domain Spore_coat_CotO PF14153.6 RLN85296.1 - 4.3 7.2 11.0 4.8 7.1 11.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF5321 PF17254.2 RLN85296.1 - 8.5 5.8 12.0 15 5.0 12.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5321) Mito_carr PF00153.27 RLN85297.1 - 2.6e-53 177.9 2.4 3.8e-21 74.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RPN6_C_helix PF18503.1 RLN85297.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.8 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain Serine_protease PF18405.1 RLN85297.1 - 0.45 9.6 2.6 1.2 8.3 0.6 2.5 3 0 0 3 3 3 0 Gammaproteobacterial serine protease EFG_IV PF03764.18 RLN85298.1 - 1.1e-36 125.2 0.2 2.6e-36 124.1 0.2 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 RLN85298.1 - 3.1e-34 116.9 0.1 7.5e-34 115.7 0.0 1.7 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 RLN85298.1 - 2.5e-25 88.3 0.0 9.7e-25 86.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 RLN85298.1 - 2.4e-11 43.9 0.4 1.1e-10 41.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 RLN85298.1 - 4.9e-07 29.6 0.0 9.9e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SLBP_RNA_bind PF15247.6 RLN85299.1 - 1.1e-11 44.7 0.2 2e-11 43.8 0.2 1.5 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain GMP_PDE_delta PF05351.11 RLN85300.1 - 2.4e-60 203.2 0.0 3e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 GMP-PDE, delta subunit Ank_4 PF13637.6 RLN85301.1 - 2.6e-35 120.3 1.7 2.4e-11 43.9 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN85301.1 - 1.5e-25 88.9 3.0 1.2e-08 35.0 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Arm PF00514.23 RLN85301.1 - 5.5e-24 83.4 14.6 4.7e-06 26.4 0.1 5.2 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat Ank_2 PF12796.7 RLN85301.1 - 1.4e-23 83.3 0.1 1.8e-15 57.3 0.0 3.4 2 2 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN85301.1 - 1e-18 65.4 0.0 1.3e-05 25.2 0.0 4.6 4 0 0 4 4 3 3 Ankyrin repeat Ank PF00023.30 RLN85301.1 - 1.1e-18 66.8 0.6 0.00026 21.3 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat HEAT_2 PF13646.6 RLN85301.1 - 2.1e-06 28.0 11.5 0.0032 17.8 1.5 3.7 1 1 3 4 4 4 4 HEAT repeats Arm_2 PF04826.13 RLN85301.1 - 0.0003 20.3 3.1 0.005 16.3 0.9 2.6 1 1 0 2 2 2 1 Armadillo-like Arm_3 PF16186.5 RLN85301.1 - 0.0073 15.9 0.0 0.24 11.0 0.0 2.5 3 0 0 3 3 3 1 Atypical Arm repeat HEAT PF02985.22 RLN85301.1 - 1.1 9.8 6.6 8 7.0 0.1 4.3 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 RLN85301.1 - 1.1 9.8 9.0 1.7 9.3 0.2 3.8 3 1 0 3 3 3 0 HEAT-like repeat HOOK PF05622.12 RLN85302.1 - 1e-26 93.4 31.4 1e-22 80.2 19.7 2.1 2 0 0 2 2 2 2 HOOK protein TPR_MLP1_2 PF07926.12 RLN85302.1 - 0.00025 21.1 8.5 0.00025 21.1 8.5 4.9 3 2 1 4 4 4 2 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 RLN85302.1 - 0.0094 16.0 12.3 0.0094 16.0 12.3 3.7 3 1 0 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3138 PF11336.8 RLN85302.1 - 0.039 12.6 5.5 0.17 10.4 0.4 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3138) F_actin_bind PF08919.10 RLN85302.1 - 0.2 11.8 0.1 0.2 11.8 0.1 4.2 5 1 0 5 5 5 0 F-actin binding kleA_kleC PF17383.2 RLN85302.1 - 1.8 9.0 15.9 0.26 11.6 0.3 5.0 4 2 1 5 5 5 0 Uncharacterized KorC regulated protein A Goodbye PF17109.5 RLN85302.1 - 3.1 8.3 5.2 0.96 9.9 0.5 2.6 3 1 0 3 3 3 0 fungal STAND N-terminal Goodbye domain Cgr1 PF03879.14 RLN85303.1 - 3e-14 53.3 20.4 3.9e-14 52.9 20.4 1.1 1 0 0 1 1 1 1 Cgr1 family CENP-Q PF13094.6 RLN85303.1 - 0.39 10.9 11.4 0.61 10.3 11.4 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit AAA_11 PF13086.6 RLN85303.1 - 1.2 8.8 9.6 1.5 8.5 9.6 1.1 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.7 RLN85304.1 - 2e-22 79.5 0.0 6.4e-09 36.3 0.1 4.4 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN85304.1 - 9.3e-21 73.9 7.4 0.00041 20.9 0.1 8.1 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN85304.1 - 1e-13 51.2 11.7 0.05 13.9 0.0 8.9 3 2 6 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN85304.1 - 3.3e-12 45.4 2.5 1.3 9.8 0.1 8.4 7 2 2 9 9 9 3 Ankyrin repeat Ank PF00023.30 RLN85304.1 - 0.00013 22.2 0.0 0.59 10.7 0.0 5.2 6 0 0 6 6 6 1 Ankyrin repeat Ig_3 PF13927.6 RLN85304.1 - 0.001 19.7 0.0 0.41 11.3 0.0 2.7 2 0 0 2 2 2 1 Immunoglobulin domain DUF249 PF03158.13 RLN85304.1 - 0.027 14.2 0.0 8.7 6.0 0.0 2.5 2 0 0 2 2 2 0 Multigene family 530 protein SLBP_RNA_bind PF15247.6 RLN85305.1 - 2.4e-07 30.7 0.0 3.9e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Alpha_GJ PF03229.13 RLN85305.1 - 0.65 10.6 8.7 0.85 10.2 8.7 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J Ten1_2 PF15490.6 RLN85306.1 - 2.4e-08 33.7 0.1 8.1e-07 28.8 0.1 2.0 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit Glyco_hydro_6 PF01341.17 RLN85308.1 - 8.4e-50 170.2 0.2 1.9e-49 169.0 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 SOG2 PF10428.9 RLN85308.1 - 1.4 8.0 24.4 1.9 7.6 24.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ank_2 PF12796.7 RLN85309.1 - 1.7e-28 99.0 4.6 5.1e-08 33.4 0.2 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN85309.1 - 2.3e-27 95.0 9.3 1.4e-07 31.9 0.0 5.6 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN85309.1 - 4e-22 78.0 7.3 0.00026 21.2 0.0 6.9 1 1 6 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN85309.1 - 5.6e-18 63.2 2.4 0.87 10.4 0.0 8.1 4 1 4 8 8 8 4 Ankyrin repeat Ank PF00023.30 RLN85309.1 - 0.013 16.0 0.8 1.4e+02 3.2 0.0 5.8 3 1 1 5 5 5 0 Ankyrin repeat MULE PF10551.9 RLN85310.1 - 7.4e-15 55.2 3.5 8.2e-15 55.0 1.1 2.3 3 0 0 3 3 3 1 MULE transposase domain DUF5575 PF17738.1 RLN85310.1 - 2.2e-08 33.5 3.0 3.3e-07 29.7 3.0 2.1 1 1 0 1 1 1 1 Family of unknown function (DUF5575) DDE_Tnp_ISL3 PF01610.17 RLN85310.1 - 0.00043 20.1 0.3 0.0012 18.7 0.3 1.8 1 0 0 1 1 1 1 Transposase Cwf_Cwc_15 PF04889.12 RLN85310.1 - 0.52 10.0 15.2 0.96 9.1 15.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 RLN85310.1 - 3.2 7.0 16.5 5 6.4 16.5 1.2 1 0 0 1 1 1 0 BUD22 Myotub-related PF06602.14 RLN85311.1 - 4.4e-125 417.3 0.0 6.3e-125 416.8 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Glycos_transf_1 PF00534.20 RLN85311.1 - 1.9e-35 121.9 0.0 4e-35 120.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 RabGAP-TBC PF00566.18 RLN85311.1 - 1.4e-27 96.7 0.0 4.9e-14 52.5 0.1 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Glyco_trans_1_4 PF13692.6 RLN85311.1 - 1.9e-18 67.2 0.0 4.9e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 RLN85311.1 - 9.3e-10 38.8 0.3 9.3e-10 38.8 0.3 2.8 3 0 0 3 3 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 RLN85311.1 - 6.1e-06 26.5 0.0 1.6e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 RLN85311.1 - 0.00074 20.0 2.8 0.0016 18.9 0.3 2.9 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain PDZ PF00595.24 RLN85311.1 - 0.0011 19.3 0.1 0.0027 18.0 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RLN85311.1 - 0.03 14.2 0.2 0.078 12.8 0.2 1.7 1 0 0 1 1 1 0 PDZ domain Y_phosphatase3 PF13350.6 RLN85311.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family GRAM PF02893.20 RLN85311.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 GRAM domain Alpha_kinase PF02816.18 RLN85312.1 - 2.8e-53 180.8 0.0 3.9e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family SHOCT PF09851.9 RLN85312.1 - 0.03 14.0 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 Short C-terminal domain DUF5082 PF16888.5 RLN85313.1 - 0.014 15.7 8.7 0.014 15.7 8.7 5.0 2 1 2 6 6 6 0 Domain of unknown function (DUF5082) Csm1_N PF18504.1 RLN85313.1 - 0.026 14.9 0.4 0.026 14.9 0.4 9.1 8 2 2 10 10 10 0 Csm1 N-terminal domain IFT57 PF10498.9 RLN85313.1 - 2.7 6.9 57.8 0.0099 14.9 9.0 3.1 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 Golgin_A5 PF09787.9 RLN85313.1 - 4.5 6.7 84.3 0.065 12.7 25.7 4.0 1 1 3 4 4 4 0 Golgin subfamily A member 5 Ketoacyl-synt_C PF02801.22 RLN85314.1 - 2.9e-34 117.6 0.7 5e-34 116.8 0.7 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 RLN85314.1 - 1.7e-22 80.3 9.1 8.7e-15 55.0 1.5 3.4 3 1 1 4 4 4 2 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 RLN85314.1 - 0.00055 19.4 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RLN85314.1 - 0.042 13.5 1.9 0.12 12.0 0.3 2.5 2 1 0 2 2 2 0 Thiolase, C-terminal domain Aldo_ket_red PF00248.21 RLN85390.1 - 5.3e-66 222.8 0.0 6e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TetR_C_14 PF17754.1 RLN85391.1 - 0.12 12.3 7.2 0.6 10.1 0.7 2.5 2 0 0 2 2 2 0 MftR C-terminal domain PDZ PF00595.24 RLN85394.1 - 6.9e-06 26.3 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RLN85394.1 - 0.006 16.4 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RLN85394.1 - 0.16 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 PDZ domain DUF3431 PF11913.8 RLN85394.1 - 0.21 11.4 0.0 5.4 6.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3431) TTL PF03133.15 RLN85395.1 - 8.2e-37 126.9 0.0 2e-35 122.4 0.0 2.0 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RLN85395.1 - 0.0028 17.0 0.0 0.0049 16.1 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp PRORP PF16953.5 RLN85396.1 - 4.7e-13 49.2 3.8 1.6e-10 40.9 0.5 4.1 2 1 0 2 2 2 1 Protein-only RNase P PPR_long PF17177.4 RLN85396.1 - 0.0013 18.1 0.0 0.0034 16.8 0.0 1.7 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP RNase_Zc3h12a PF11977.8 RLN85396.1 - 0.05 13.4 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain RecQ_Zn_bind PF16124.5 RLN85396.1 - 0.18 12.6 1.0 8 7.3 0.1 3.0 2 1 1 3 3 3 0 RecQ zinc-binding ZZ PF00569.17 RLN85397.1 - 6.3e-07 29.1 0.8 1.2e-06 28.3 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type DnaJ_CXXCXGXG PF00684.19 RLN85397.1 - 0.027 14.8 4.5 0.2 12.1 3.8 2.2 1 1 1 2 2 2 0 DnaJ central domain zf-SNAP50_C PF12251.8 RLN85397.1 - 0.17 11.6 0.1 0.24 11.0 0.1 1.2 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal Asp PF00026.23 RLN85398.1 - 2.1e-36 126.0 0.0 2.7e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RLN85398.1 - 3.3e-12 47.0 0.3 8.4e-07 29.4 0.0 2.4 1 1 0 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 RLN85398.1 - 3.4e-08 33.4 0.0 6.1e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 RLN85398.1 - 0.0038 17.8 0.3 2 9.1 0.1 2.8 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 RLN85398.1 - 0.011 16.3 0.0 11 6.7 0.0 2.8 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease YihI PF04220.12 RLN85400.1 - 8.8 6.0 8.1 16 5.2 8.1 1.5 1 1 0 1 1 1 0 Der GTPase activator (YihI) META PF03724.16 RLN85401.1 - 0.099 12.6 0.6 24 5.0 0.1 2.8 3 0 0 3 3 3 0 META domain lci PF12197.8 RLN85402.1 - 0.089 12.6 0.8 0.19 11.5 0.8 1.5 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein RRM_1 PF00076.22 RLN85403.1 - 1.4e-13 50.5 0.0 2e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dimer_Tnp_hAT PF05699.14 RLN85404.1 - 3.9e-05 23.4 0.1 8.3e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 RLN85404.1 - 0.025 14.6 1.1 0.1 12.6 0.3 2.3 2 0 0 2 2 2 0 BED zinc finger Arm PF00514.23 RLN85405.1 - 2.7e-27 93.9 4.9 5.4e-05 23.1 0.0 6.6 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN85405.1 - 2e-16 58.6 3.3 0.72 10.3 0.0 6.4 6 0 0 6 6 6 5 HEAT repeat HEAT_EZ PF13513.6 RLN85405.1 - 3.2e-11 43.5 15.0 0.001 19.5 0.2 4.7 4 1 0 4 4 4 3 HEAT-like repeat HEAT_2 PF13646.6 RLN85405.1 - 5.8e-11 42.6 35.3 0.00013 22.3 2.3 4.1 1 1 5 6 6 6 6 HEAT repeats Tox-MPTase3 PF15639.6 RLN85405.1 - 5.7e-07 29.5 0.1 1.3 8.9 0.0 5.0 1 1 3 4 4 4 2 Metallopeptidase toxin 3 HEAT_PBS PF03130.16 RLN85405.1 - 2e-05 24.8 24.4 7.6 7.5 0.1 7.1 7 0 0 7 7 7 2 PBS lyase HEAT-like repeat SelB-wing_1 PF09105.10 RLN85405.1 - 0.00041 20.3 6.1 5.9 6.9 0.1 5.5 5 0 0 5 5 5 1 Elongation factor SelB, winged helix ATP-synt_F PF01990.17 RLN85405.1 - 0.0008 19.7 1.4 12 6.4 0.0 4.4 1 1 2 4 4 4 1 ATP synthase (F/14-kDa) subunit PfaD_N PF18328.1 RLN85405.1 - 0.0084 16.0 0.8 1.3e+02 2.6 0.0 4.5 4 0 0 4 4 4 0 Fatty acid synthase subunit PfaD N-terminal domain Adaptin_N PF01602.20 RLN85405.1 - 0.015 13.9 0.0 3.4 6.1 0.0 2.2 1 1 1 2 2 2 0 Adaptin N terminal region PIN_2 PF10130.9 RLN85405.1 - 0.019 15.2 15.4 5.5 7.2 0.0 5.6 2 2 4 6 6 6 0 PIN domain DUF1804 PF08822.11 RLN85405.1 - 0.064 13.2 1.0 15 5.6 0.1 3.9 1 1 3 5 5 5 0 Protein of unknown function (DUF1804) fn3_3 PF14686.6 RLN85405.1 - 0.19 11.6 0.2 49 3.8 0.0 3.6 4 0 0 4 4 4 0 Polysaccharide lyase family 4, domain II Antimicrobial17 PF08129.11 RLN85405.1 - 0.92 9.5 17.1 63 3.7 0.1 6.6 7 0 0 7 7 7 0 Alpha/beta enterocin family RNase_HII PF01351.18 RLN85406.1 - 1.7e-16 60.7 0.0 1.9e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Sugar_tr PF00083.24 RLN85407.1 - 0.076 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter FAM104 PF15434.6 RLN85409.1 - 0.14 12.7 0.0 0.14 12.7 0.0 1.3 1 1 0 1 1 1 0 Family 104 bZIP_1 PF00170.21 RLN85410.1 - 0.042 13.9 9.0 1.1 9.4 8.9 2.5 2 1 0 2 2 2 0 bZIP transcription factor AKAP7_RIRII_bdg PF10470.9 RLN85410.1 - 0.057 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein DUF1140 PF06600.11 RLN85410.1 - 0.16 12.4 0.1 0.29 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1140) bZIP_2 PF07716.15 RLN85410.1 - 1.9 8.6 7.1 3.3 7.9 5.4 2.0 2 0 0 2 2 2 0 Basic region leucine zipper Pkinase_Tyr PF07714.17 RLN85411.1 - 3.4e-20 72.4 0.0 2.1e-17 63.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN85411.1 - 4.2e-17 62.4 0.0 5.1e-16 58.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 RLN85411.1 - 3.5e-06 26.7 0.1 8e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 RLN85411.1 - 1.9e-05 24.9 0.1 7.7e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) zf-C2H2_jaz PF12171.8 RLN85412.1 - 0.00074 19.7 2.6 0.0016 18.7 2.6 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RLN85412.1 - 0.081 13.3 1.9 0.15 12.5 1.9 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type LicD PF04991.13 RLN85412.1 - 0.56 10.3 4.8 0.75 9.9 4.8 1.2 1 0 0 1 1 1 0 LicD family CDC45 PF02724.14 RLN85412.1 - 1.6 7.0 22.9 1.8 6.7 22.9 1.1 1 0 0 1 1 1 0 CDC45-like protein EOS1 PF12326.8 RLN85412.1 - 1.6 8.6 2.9 2 8.3 2.9 1.4 1 0 0 1 1 1 0 N-glycosylation protein PPP4R2 PF09184.11 RLN85412.1 - 4.3 6.8 20.3 5.6 6.5 20.3 1.3 1 0 0 1 1 1 0 PPP4R2 GAGA_bind PF06217.12 RLN85412.1 - 6.5 7.0 14.5 8 6.7 14.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family LMBR1 PF04791.16 RLN85412.1 - 8.4 5.2 7.0 8.9 5.1 7.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2828 PF11443.8 RLN85412.1 - 9.6 4.2 12.7 10 4.1 12.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Arf PF00025.21 RLN85413.1 - 2.1e-33 115.2 0.0 3.6e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 RLN85413.1 - 7.7e-09 35.2 0.0 1.6e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RLN85413.1 - 3.5e-08 33.0 0.0 1.9e-05 24.0 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 RLN85413.1 - 4.2e-07 30.2 0.0 8.3e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RLN85413.1 - 1.1e-05 25.1 0.0 2.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 RLN85413.1 - 2.2e-05 24.5 0.0 4.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TUDOR_5 PF18359.1 RLN85413.1 - 0.00075 19.2 0.1 0.0017 18.0 0.1 1.6 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 Tudor_3 PF18115.1 RLN85413.1 - 0.0026 17.5 0.0 0.0058 16.5 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF1325 PF07039.11 RLN85413.1 - 0.0061 16.6 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4537 PF15057.6 RLN85413.1 - 0.0066 16.5 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) cobW PF02492.19 RLN85413.1 - 0.013 15.1 0.4 0.87 9.1 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 RLN85413.1 - 0.022 15.0 0.0 0.063 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RLN85413.1 - 0.023 15.2 0.5 0.068 13.7 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 RLN85413.1 - 0.032 14.6 1.0 0.082 13.3 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.15 RLN85413.1 - 0.038 13.9 0.4 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 RLN85413.1 - 0.045 13.7 0.1 0.15 12.0 0.1 1.9 2 0 0 2 2 2 0 NACHT domain LBR_tudor PF09465.10 RLN85413.1 - 0.065 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain AAA_33 PF13671.6 RLN85413.1 - 0.066 13.4 0.5 0.11 12.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain Septin PF00735.18 RLN85413.1 - 0.081 12.2 0.4 0.78 9.0 0.0 2.2 2 0 0 2 2 2 0 Septin Thymidylate_kin PF02223.17 RLN85413.1 - 0.1 12.2 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 Thymidylate kinase AAA_24 PF13479.6 RLN85413.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 RLN85413.1 - 0.13 11.8 0.2 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cNMP_binding PF00027.29 RLN85506.1 - 3.6e-14 52.6 0.0 5.2e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ank_4 PF13637.6 RLN85507.1 - 8.2e-45 150.6 19.4 2.7e-06 27.8 0.0 10.6 8 2 3 11 11 11 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN85507.1 - 1.2e-40 137.9 5.0 4.3e-09 36.8 0.1 7.1 3 1 4 9 9 9 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN85507.1 - 4.3e-29 100.2 29.9 0.003 17.8 0.0 14.6 7 2 8 15 15 15 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN85507.1 - 5.5e-25 84.7 11.4 3 8.7 0.0 16.0 15 1 1 16 16 16 6 Ankyrin repeat DUF5049 PF16468.5 RLN85507.1 - 6.1e-05 22.8 0.0 67 3.5 0.0 7.0 3 2 5 8 8 8 0 Domain of unknown function (DUF5049) Ank PF00023.30 RLN85507.1 - 0.00022 21.5 2.2 26 5.5 0.3 7.9 3 1 2 5 5 5 0 Ankyrin repeat DUF1843 PF08898.10 RLN85507.1 - 0.0058 17.1 3.2 26 5.4 0.0 6.5 10 0 0 10 10 10 0 Domain of unknown function (DUF1843) CNOT1_HEAT PF16418.5 RLN85507.1 - 0.47 10.5 3.9 77 3.3 0.0 5.4 6 1 0 6 6 6 0 CCR4-NOT transcription complex subunit 1 HEAT repeat EamA PF00892.20 RLN85508.1 - 6.1e-52 175.4 52.1 4.6e-19 68.9 8.3 4.2 3 1 1 4 4 4 4 EamA-like transporter family TPT PF03151.16 RLN85508.1 - 0.00022 20.7 35.9 0.11 11.8 4.0 3.3 2 1 1 3 3 3 3 Triose-phosphate Transporter family Gram_pos_anchor PF00746.21 RLN85508.1 - 0.56 10.2 0.0 0.56 10.2 0.0 4.5 4 0 0 4 4 4 0 LPXTG cell wall anchor motif DAD PF02109.16 RLN85508.1 - 3.3 8.0 16.7 0.75 10.1 1.7 3.8 2 1 0 3 3 3 0 DAD family EamA PF00892.20 RLN85509.1 - 1.3e-21 77.2 27.3 2e-14 53.9 10.4 3.2 3 0 0 3 3 3 3 EamA-like transporter family DUF4229 PF14012.6 RLN85509.1 - 7.8 6.7 8.9 18 5.5 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) Sod_Fe_C PF02777.18 RLN85510.1 - 0.072 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, C-terminal domain NPR1_like_C PF12313.8 RLN85511.1 - 0.015 14.8 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 NPR1/NIM1 like defence protein C terminal Pkinase PF00069.25 RLN85512.1 - 3.4e-45 154.5 0.0 4.4e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN85512.1 - 8.2e-23 81.0 0.0 3.9e-22 78.8 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 RLN85512.1 - 3e-05 24.0 0.4 0.00076 19.5 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN85512.1 - 0.01 15.2 0.1 0.022 14.1 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN85512.1 - 0.059 12.1 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 RLN85512.1 - 0.15 11.3 0.4 0.54 9.5 0.4 1.8 1 1 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 RLN85512.1 - 0.18 10.7 0.1 0.29 10.0 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain UQ_con PF00179.26 RLN85513.1 - 6e-21 74.6 0.2 8.2e-14 51.4 0.1 2.4 2 1 0 2 2 2 2 Ubiquitin-conjugating enzyme FA_hydroxylase PF04116.13 RLN85514.1 - 4.9e-17 62.5 18.3 4.9e-17 62.5 18.3 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily APG9 PF04109.16 RLN85515.1 - 1.8e-146 489.0 4.8 2.1e-146 488.7 4.8 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Telomerase_RBD PF12009.8 RLN85515.1 - 0.028 14.5 0.6 0.064 13.4 0.6 1.6 1 0 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain Sugar_tr PF00083.24 RLN85517.1 - 0.015 14.2 0.1 0.018 13.9 0.1 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter Pkinase PF00069.25 RLN85518.1 - 3.2e-49 167.7 0.0 3.1e-34 118.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN85518.1 - 5.3e-49 166.8 0.0 1.1e-31 110.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase BatD PF13584.6 RLN85518.1 - 0.0016 17.3 0.0 0.0023 16.8 0.0 1.1 1 0 0 1 1 1 1 Oxygen tolerance Podoplanin PF05808.11 RLN85518.1 - 0.0075 16.4 1.2 0.022 14.9 0.8 2.0 2 0 0 2 2 2 1 Podoplanin TMEM154 PF15102.6 RLN85518.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family DUF1180 PF06679.12 RLN85518.1 - 0.015 15.7 0.2 0.031 14.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Trp_oprn_chp PF09534.10 RLN85518.1 - 0.028 14.2 1.7 0.045 13.5 0.1 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CD34_antigen PF06365.12 RLN85518.1 - 0.034 13.7 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Peptidase_M56 PF05569.11 RLN85518.1 - 0.057 12.6 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 Amnionless PF14828.6 RLN85518.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Amnionless Haspin_kinase PF12330.8 RLN85518.1 - 0.18 10.7 0.1 0.34 9.8 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF5305 PF17231.2 RLN85518.1 - 0.19 11.1 0.2 0.33 10.3 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Kdo PF06293.14 RLN85518.1 - 0.2 11.0 0.1 0.34 10.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rb_C PF08934.10 RLN85519.1 - 0.041 13.7 3.0 3.5 7.4 0.0 2.7 2 0 0 2 2 2 0 Rb C-terminal domain Ank_2 PF12796.7 RLN85590.1 - 1.2e-242 785.2 58.0 5.4e-22 78.2 0.2 15.1 1 1 14 17 17 17 17 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN85590.1 - 2.8e-159 497.3 31.7 1.8e-06 27.8 0.0 30.8 31 0 0 31 31 31 30 Ankyrin repeat Ank PF00023.30 RLN85590.1 - 7.2e-157 503.7 50.3 6.3e-07 29.6 0.0 30.6 30 1 1 31 31 31 30 Ankyrin repeat Ank_4 PF13637.6 RLN85590.1 - 4.4e-148 479.9 49.1 8.7e-11 42.1 0.1 24.2 6 5 17 25 25 25 25 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN85590.1 - 1.2e-144 468.5 79.5 2e-09 37.5 0.1 27.6 1 1 27 29 29 29 28 Ankyrin repeats (many copies) MEDS PF14417.6 RLN85590.1 - 9.3e-07 28.8 14.5 2.7 7.8 0.0 7.8 3 2 6 9 9 9 3 MEDS: MEthanogen/methylotroph, DcmR Sensory domain YfmQ PF10787.9 RLN85590.1 - 1.1e-06 28.5 0.0 6.5 6.5 0.0 8.9 7 3 4 11 11 11 1 Uncharacterised protein from bacillus cereus group Nepo_coat_C PF03688.14 RLN85590.1 - 1.5e-05 24.9 20.3 13 5.6 0.2 10.1 5 2 6 14 14 14 1 Nepovirus coat protein, C-terminal domain YlzJ PF14035.6 RLN85590.1 - 2.4e-05 24.4 0.0 2.7e+02 1.8 0.0 10.4 14 1 1 15 15 14 0 YlzJ-like protein DUF2390 PF09523.10 RLN85590.1 - 0.00014 22.1 13.8 2.6 8.4 0.0 8.9 4 3 7 11 11 11 1 Protein of unknown function (DUF2390) FliT PF05400.13 RLN85590.1 - 0.11 13.3 0.6 16 6.4 0.1 4.4 3 0 0 3 3 3 0 Flagellar protein FliT VWA_3_C PF18571.1 RLN85590.1 - 0.65 9.9 32.0 40 4.2 0.0 14.7 19 1 1 20 20 20 0 von Willebrand factor type A C-terminal domain IRK_N PF08466.10 RLN85590.1 - 4.5 7.5 4.6 30 4.9 0.0 5.1 7 0 0 7 7 6 0 Inward rectifier potassium channel N-terminal zf-Nse PF11789.8 RLN85591.1 - 0.00097 18.9 0.4 0.0018 18.0 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit TerY_C PF15616.6 RLN85591.1 - 0.02 15.0 0.2 0.039 14.1 0.2 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_UBOX PF13445.6 RLN85591.1 - 0.024 14.7 1.9 0.047 13.7 1.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Wtap PF17098.5 RLN85591.1 - 0.038 13.9 2.4 0.076 12.9 2.4 1.4 1 0 0 1 1 1 0 WTAP/Mum2p family zf-RING_10 PF16685.5 RLN85591.1 - 0.11 12.7 1.9 0.2 11.8 1.9 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 U-box PF04564.15 RLN85591.1 - 0.18 12.0 0.0 0.47 10.7 0.0 1.8 1 0 0 1 1 1 0 U-box domain zf-RING_2 PF13639.6 RLN85591.1 - 0.28 11.6 2.8 0.51 10.7 2.8 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 RLN85591.1 - 0.53 10.2 3.1 0.93 9.4 3.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 RLN85592.1 - 0.0049 16.7 0.2 0.0091 15.8 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit HOOK PF05622.12 RLN85592.1 - 0.028 12.6 4.2 0.037 12.2 4.2 1.1 1 0 0 1 1 1 0 HOOK protein zf-RING_UBOX PF13445.6 RLN85592.1 - 0.21 11.7 2.5 0.45 10.6 2.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger AP1AR PF15745.5 RLN85592.1 - 0.75 9.4 4.8 1.4 8.5 4.8 1.3 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein DivIC PF04977.15 RLN85592.1 - 0.98 9.2 3.4 1.9 8.3 3.4 1.5 1 0 0 1 1 1 0 Septum formation initiator Rho_Binding PF08912.11 RLN85592.1 - 1.4 9.8 6.0 5.1 8.0 5.8 2.0 2 0 0 2 2 2 0 Rho Binding zf-Nse PF11789.8 RLN85594.1 - 0.0047 16.7 1.6 0.0096 15.7 1.6 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 RLN85594.1 - 0.024 15.0 3.4 0.053 13.9 3.4 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 RLN85594.1 - 0.1 12.5 4.6 0.23 11.3 4.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN85594.1 - 0.7 9.9 3.1 1.9 8.5 3.0 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 RLN85594.1 - 0.99 9.5 3.7 1 9.4 2.3 1.9 1 1 0 1 1 1 0 RING-type zinc-finger Cellulase PF00150.18 RLN85595.1 - 3e-27 95.8 0.0 4e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) EGF_2 PF07974.13 RLN85595.1 - 0.038 14.4 19.8 0.038 14.4 19.8 3.6 3 0 0 3 3 3 0 EGF-like domain Fascin PF06268.13 RLN85596.1 - 0.0023 18.1 0.1 0.0034 17.6 0.1 1.3 1 0 0 1 1 1 1 Fascin domain DUF5414 PF17435.2 RLN85597.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5414) Barttin PF15462.6 RLN85597.1 - 0.16 11.8 1.4 0.31 10.8 1.4 1.5 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Fascin PF06268.13 RLN85598.1 - 0.015 15.5 0.1 0.025 14.8 0.1 1.5 1 0 0 1 1 1 0 Fascin domain Enterotoxin_b PF01376.18 RLN85598.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Heat-labile enterotoxin beta chain Inh PF02974.14 RLN85598.1 - 0.16 12.0 0.9 0.36 10.9 0.5 1.7 1 1 1 2 2 2 0 Protease inhibitor Inh Kazal_1 PF00050.21 RLN85663.1 - 2.1e-11 43.6 5.1 2.9e-11 43.2 5.1 1.2 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 RLN85663.1 - 6.1e-09 35.9 5.9 8.6e-09 35.4 5.9 1.2 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain ERGIC_N PF13850.6 RLN85664.1 - 1.4e-17 63.8 0.0 1.7e-17 63.5 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ACOX PF01756.19 RLN85668.1 - 1.2e-47 161.9 0.0 1.5e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA oxidase DUF667 PF05018.13 RLN85669.1 - 5.2e-27 94.8 0.0 1e-26 93.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF667) FAR1 PF03101.15 RLN85669.1 - 6.3e-09 36.4 13.0 0.029 15.0 1.0 4.8 4 0 0 4 4 4 3 FAR1 DNA-binding domain Cauli_VI PF01693.16 RLN85669.1 - 0.0027 18.0 0.2 0.11 12.8 0.0 2.9 2 0 0 2 2 2 1 Caulimovirus viroplasmin DUF3319 PF11782.8 RLN85669.1 - 0.12 12.4 0.0 2.7 8.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3319) PDEase_I PF00233.19 RLN85670.1 - 1.9e-79 266.7 1.7 2.8e-79 266.2 1.7 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ion_trans PF00520.31 RLN85670.1 - 9.1e-10 38.2 9.1 1.5e-09 37.4 9.1 1.3 1 0 0 1 1 1 1 Ion transport protein Pkinase_Tyr PF07714.17 RLN85759.1 - 1e-42 146.3 0.0 7.8e-23 81.1 0.0 3.1 2 1 1 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 RLN85759.1 - 3.6e-41 141.3 0.0 3.5e-21 75.8 0.0 3.2 2 1 1 3 3 3 3 Protein kinase domain Kinase-like PF14531.6 RLN85759.1 - 0.00074 18.9 0.0 0.36 10.1 0.0 2.7 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 RLN85759.1 - 0.0027 17.1 1.1 2.3 7.5 0.0 3.3 4 0 0 4 4 4 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RLN85759.1 - 0.0099 15.5 0.0 1.5 8.4 0.0 2.6 2 0 0 2 2 2 1 RIO1 family DnaT PF17948.1 RLN85759.1 - 0.023 14.4 0.1 0.078 12.7 0.1 1.9 1 0 0 1 1 1 0 DnaT DNA-binding domain APH PF01636.23 RLN85759.1 - 0.024 14.5 0.1 0.13 12.2 0.1 4.1 4 2 0 4 4 4 0 Phosphotransferase enzyme family Varsurf_PPLC PF03490.13 RLN85760.1 - 0.13 12.2 0.3 1.9 8.5 0.3 2.2 2 0 0 2 2 2 0 Variant-surface-glycoprotein phospholipase C Epimerase PF01370.21 RLN85761.1 - 8.3e-29 100.7 0.0 1.2e-28 100.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RLN85761.1 - 1.2e-20 74.3 0.5 9.5e-20 71.2 0.5 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 RLN85761.1 - 3.9e-13 49.1 0.0 5.4e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RLN85761.1 - 1.3e-11 44.2 1.3 5.2e-10 38.9 1.3 2.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 RLN85761.1 - 7.7e-11 41.5 0.0 1.1e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 RLN85761.1 - 2.8e-07 30.0 0.1 1.1e-06 28.0 0.0 2.0 2 1 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 RLN85761.1 - 0.00022 21.2 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 RLN85761.1 - 0.013 15.4 0.6 0.11 12.5 0.6 2.1 1 1 0 1 1 1 0 KR domain NmrA PF05368.13 RLN85761.1 - 0.014 14.9 0.1 0.4 10.2 0.1 2.2 2 0 0 2 2 2 0 NmrA-like family Actin PF00022.19 RLN85762.1 - 1.7e-09 36.8 0.0 1.9e-09 36.6 0.0 1.0 1 0 0 1 1 1 1 Actin LIX1 PF14954.6 RLN85762.1 - 0.11 11.8 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Limb expression 1 Aldo_ket_red PF00248.21 RLN85763.1 - 1.2e-21 77.2 0.1 3.6e-13 49.4 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Aldo_ket_red PF00248.21 RLN85764.1 - 4.1e-71 239.6 0.0 4.7e-71 239.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family cNMP_binding PF00027.29 RLN85765.1 - 1.7e-42 143.4 2.7 1.9e-11 43.9 0.1 5.0 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN85765.1 - 9.1e-34 116.8 36.8 7e-13 48.4 1.6 4.6 4 1 0 4 4 4 4 Ion transport protein baeRF_family12 PF18856.1 RLN85765.1 - 0.19 12.3 1.9 0.56 10.8 1.9 1.8 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 Ion_trans PF00520.31 RLN85766.1 - 6.9e-37 127.0 14.6 6.9e-37 127.0 14.6 1.5 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 RLN85766.1 - 3.3e-13 49.4 3.1 3.3e-13 49.4 3.1 2.6 3 0 0 3 3 3 1 Ion channel EF-hand_1 PF00036.32 RLN85766.1 - 0.0087 15.5 1.2 0.02 14.4 1.2 1.7 1 0 0 1 1 1 1 EF hand HTH_Bact PF18768.1 RLN85766.1 - 0.026 14.1 0.1 0.062 12.9 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix bacterial domain DnaJ PF00226.31 RLN85767.1 - 1.9e-16 59.9 1.1 9.4e-10 38.5 0.2 2.2 2 0 0 2 2 2 2 DnaJ domain zf-CSL PF05207.13 RLN85767.1 - 2.2e-13 49.7 0.4 2.2e-13 49.7 0.4 1.9 2 0 0 2 2 2 1 CSL zinc finger Myosin_tail_1 PF01576.19 RLN85767.1 - 0.0067 14.3 1.5 0.008 14.1 1.5 1.0 1 0 0 1 1 1 1 Myosin tail AKAP95 PF04988.12 RLN85767.1 - 0.11 12.8 0.2 0.49 10.6 0.0 1.9 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) ATP-synt_S1 PF05827.12 RLN85768.1 - 0.044 13.6 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) CHASE5 PF17149.4 RLN85768.1 - 0.087 12.8 0.0 2.5 8.1 0.0 2.2 1 1 1 2 2 2 0 Periplasmic sensor domain found in signal transduction proteins RRM_1 PF00076.22 RLN85769.1 - 3.7e-15 55.5 0.0 5.8e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SWIRM-assoc_2 PF16496.5 RLN85769.1 - 0.51 9.2 2.0 0.67 8.8 2.0 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal FoP_duplication PF13865.6 RLN85770.1 - 3.6e-05 24.2 11.7 0.00033 21.2 0.3 2.2 2 0 0 2 2 2 2 C-terminal duplication domain of Friend of PRMT1 PseudoU_synth_1 PF01416.20 RLN85771.1 - 4.2e-15 56.1 0.2 3.2e-13 50.1 0.0 2.5 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF2344 PF10105.9 RLN85771.1 - 0.03 14.2 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) UPF0176_N PF17773.1 RLN85771.1 - 0.063 13.6 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 UPF0176 acylphosphatase like domain Peptidase_M16_C PF05193.21 RLN85772.1 - 8.6e-35 120.4 0.0 1.4e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 RLN85772.1 - 4.5e-25 88.4 0.0 3.6e-21 75.7 0.0 2.8 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) Steroid_dh PF02544.16 RLN85776.1 - 1.1e-46 158.5 0.0 2.4e-46 157.4 0.0 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase GTP_EFTU PF00009.27 RLN85776.1 - 1.7e-36 125.6 1.3 3.3e-36 124.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 RLN85776.1 - 2.3e-17 63.0 0.0 6.6e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 DUF1295 PF06966.12 RLN85776.1 - 3.5e-07 30.0 0.0 7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) MMR_HSR1 PF01926.23 RLN85776.1 - 6.3e-07 29.5 0.4 2.1e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 RLN85776.1 - 1.8e-06 28.2 1.6 3.4e-06 27.3 0.4 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 ATP_bind_1 PF03029.17 RLN85776.1 - 2.8e-05 24.0 0.0 0.00013 21.8 0.0 2.2 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein PEMT PF04191.13 RLN85776.1 - 0.00012 22.5 0.1 0.00027 21.3 0.1 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase Roc PF08477.13 RLN85776.1 - 0.0025 18.0 0.0 0.0064 16.7 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 RLN85776.1 - 0.048 13.9 0.1 0.3 11.4 0.1 2.3 1 1 0 1 1 1 0 AAA domain BfiI_DBD PF18243.1 RLN85777.1 - 0.0034 17.0 0.1 0.005 16.5 0.1 1.4 1 0 0 1 1 1 1 Metal-independent restriction enzyme BfiI DNA binding domain TPR_2 PF07719.17 RLN85778.1 - 1.4e-07 31.1 5.7 0.3 11.3 0.5 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN85778.1 - 2.1e-06 27.5 2.9 0.2 12.0 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN85778.1 - 4.7e-06 26.2 3.3 0.36 10.7 0.0 4.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN85778.1 - 1.6e-05 24.5 0.1 0.00017 21.2 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 RLN85778.1 - 0.0003 20.9 0.8 0.004 17.4 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN85778.1 - 0.0006 20.3 2.2 0.07 13.7 0.2 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN85778.1 - 0.00071 20.2 0.4 16 6.6 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN85778.1 - 0.0025 18.0 0.6 0.36 11.1 0.4 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 RLN85778.1 - 0.0073 16.6 2.4 0.49 10.7 0.1 3.4 2 2 0 2 2 2 1 Tetratricopeptide repeat WD40 PF00400.32 RLN85779.1 - 5.9e-45 150.3 23.4 2.5e-10 40.8 0.6 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN85779.1 - 8.2e-24 83.7 4.6 1.7e-05 25.0 0.0 7.3 3 2 4 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RLN85779.1 - 4e-10 39.9 0.8 0.0013 18.6 0.2 4.5 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 RLN85779.1 - 0.0013 18.6 2.5 0.02 14.8 0.1 2.6 2 0 0 2 2 2 1 LisH Nup160 PF11715.8 RLN85779.1 - 0.016 13.9 1.3 1.2 7.7 0.0 3.8 4 1 0 4 4 4 0 Nucleoporin Nup120/160 WD40_like PF17005.5 RLN85779.1 - 0.037 13.4 0.0 4 6.7 0.0 2.8 3 1 1 4 4 4 0 WD40-like domain IKI3 PF04762.12 RLN85779.1 - 0.13 10.2 0.9 1.2 7.1 0.1 2.2 1 1 1 2 2 2 0 IKI3 family DZR PF12773.7 RLN85780.1 - 0.0012 18.9 35.4 0.53 10.4 2.1 4.3 4 0 0 4 4 4 4 Double zinc ribbon zf-CCHC_6 PF15288.6 RLN85780.1 - 0.0058 16.5 29.8 0.051 13.4 2.4 5.2 4 1 1 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.6 RLN85780.1 - 0.032 14.1 33.5 0.34 10.8 2.7 5.6 5 0 0 5 5 5 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 RLN85780.1 - 1.2 9.6 27.3 1.9 8.9 9.1 4.1 3 1 0 3 3 3 0 DnaJ central domain FYVE PF01363.21 RLN85780.1 - 4.6 7.5 49.4 1 9.5 9.1 4.4 1 1 2 4 4 4 0 FYVE zinc finger Pkinase PF00069.25 RLN85781.1 - 8.2e-46 156.5 0.0 1.2e-45 156.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN85781.1 - 8.8e-40 136.6 0.0 1.3e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN85781.1 - 0.032 13.0 0.0 0.049 12.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase TIR_2 PF13676.6 RLN85782.1 - 2.9e-12 47.2 0.0 5.3e-07 30.3 0.0 3.1 2 1 0 2 2 2 2 TIR domain AAA_16 PF13191.6 RLN85782.1 - 0.003 18.0 0.0 0.007 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain IQ PF00612.27 RLN85783.1 - 2.8e-21 73.2 43.1 0.0044 16.7 0.1 8.8 8 0 0 8 8 8 7 IQ calmodulin-binding motif Como_SCP PF02248.16 RLN85783.1 - 0.073 12.6 1.1 0.12 12.0 0.1 1.8 2 0 0 2 2 2 0 Small coat protein Quaking_NLS PF16551.5 RLN85783.1 - 0.087 12.5 0.2 9 6.1 0.1 2.7 2 0 0 2 2 2 0 Putative nuclear localisation signal of quaking DUF5033 PF16436.5 RLN85783.1 - 0.091 12.7 0.6 0.23 11.4 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5033) WD40 PF00400.32 RLN85787.1 - 2.1e-43 145.4 20.3 5.5e-09 36.5 0.1 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN85787.1 - 9.3e-18 64.3 5.3 0.0032 17.7 0.0 6.2 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 RLN85787.1 - 2.8e-05 22.4 6.3 0.00021 19.4 5.1 2.4 1 1 0 1 1 1 1 IKI3 family Gmad1 PF10647.9 RLN85787.1 - 0.0023 17.7 5.1 0.16 11.7 1.7 4.3 1 1 2 3 3 3 2 Lipoprotein LpqB beta-propeller domain DUF2387 PF09526.10 RLN85787.1 - 0.015 15.4 2.5 3.2 8.0 0.1 3.7 3 0 0 3 3 3 0 Probable metal-binding protein (DUF2387) Coatomer_WDAD PF04053.14 RLN85787.1 - 0.25 10.4 0.3 0.64 9.0 0.1 1.9 2 0 0 2 2 2 0 Coatomer WD associated region Homeodomain PF00046.29 RLN85788.1 - 8.8e-05 22.3 3.4 0.042 13.7 0.8 2.8 2 1 0 2 2 2 2 Homeodomain TMEM247 PF15444.6 RLN85788.1 - 1.3 9.0 5.6 0.33 11.0 0.9 2.4 2 0 0 2 2 2 0 Transmembrane protein 247 RXT2_N PF08595.11 RLN85788.1 - 7.7 6.5 15.2 9.3 6.3 8.3 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal CNDH2_C PF16858.5 RLN85788.1 - 8.5 6.2 13.3 1.4 8.8 8.8 1.9 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop14 PF04147.12 RLN85788.1 - 9 4.4 20.6 0.16 10.2 12.5 1.9 2 0 0 2 2 2 0 Nop14-like family TPR_16 PF13432.6 RLN85789.1 - 1.9e-08 34.8 0.2 1.6e-06 28.6 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 RLN85789.1 - 2.8e-06 27.0 0.2 0.043 13.9 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN85789.1 - 2.1e-05 24.1 0.1 2.1e-05 24.1 0.1 1.8 2 0 0 2 2 2 1 TPR repeat TPR_9 PF13371.6 RLN85789.1 - 0.00021 21.4 0.3 0.0007 19.7 0.3 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN85789.1 - 0.0004 20.5 0.1 0.0018 18.5 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN85789.1 - 0.00041 20.0 0.0 0.66 9.9 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN85789.1 - 0.00064 20.3 0.5 0.057 14.3 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN85789.1 - 0.1 12.8 0.0 2.2 8.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat GAF_2 PF13185.6 RLN85790.1 - 1.1e-09 38.8 0.1 3.7e-09 37.0 0.1 1.8 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 RLN85790.1 - 1.3e-05 25.8 0.0 1.8e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 RLN85790.1 - 0.03 14.6 0.0 0.063 13.6 0.0 1.5 1 0 0 1 1 1 0 GAF domain RNase_H PF00075.24 RLN85878.1 - 6.9e-19 68.4 0.0 1.2e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 RLN85878.1 - 5.1e-13 49.1 0.8 5.1e-13 49.1 0.8 2.2 3 0 0 3 3 3 1 Caulimovirus viroplasmin RNase_H PF00075.24 RLN85879.1 - 4.4e-28 98.3 0.0 6.4e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 RLN85879.1 - 5.6e-09 36.2 0.3 1.2e-08 35.1 0.3 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin Anoctamin PF04547.12 RLN85881.1 - 1.1e-121 406.9 14.1 1.4e-121 406.5 14.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF2207 PF09972.9 RLN85881.1 - 0.0096 14.7 1.6 0.049 12.4 0.0 2.4 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) OppC_N PF12911.7 RLN85881.1 - 0.11 12.5 0.1 0.4 10.7 0.1 2.0 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C FAD_binding_7 PF03441.14 RLN85882.1 - 0.047 13.2 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase MitMem_reg PF13012.6 RLN85883.1 - 5.7e-34 116.9 0.3 9.7e-34 116.2 0.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 RLN85883.1 - 3.3e-25 88.4 0.0 6.6e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TRPM_tetra PF16519.5 RLN85883.1 - 0.14 12.2 0.8 3.4 7.8 0.1 2.5 2 0 0 2 2 2 0 Tetramerisation domain of TRPM Glyco_hydro_47 PF01532.20 RLN85884.1 - 4.4e-123 411.6 0.1 5.1e-122 408.0 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 MLANA PF14991.6 RLN85885.1 - 0.18 12.1 0.1 0.56 10.5 0.1 1.8 1 0 0 1 1 1 0 Protein melan-A HTH_Tnp_Tc5 PF03221.16 RLN85886.1 - 4.8e-10 39.3 0.0 1.3e-09 37.9 0.0 1.7 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Meckelin PF09773.9 RLN85887.1 - 1.5e-132 443.5 0.1 2e-132 443.0 0.1 1.1 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) Ephrin_rec_like PF07699.13 RLN85887.1 - 0.97 9.2 3.5 0.56 10.0 0.4 2.1 2 0 0 2 2 2 0 Putative ephrin-receptor like PRKCSH_1 PF13015.6 RLN85888.1 - 8.3e-09 35.3 1.0 1.5e-08 34.5 1.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 RLN85888.1 - 1.1e-08 36.0 1.0 2.4e-08 34.9 1.0 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Yippee-Mis18 PF03226.14 RLN85888.1 - 0.0058 16.8 0.9 0.0058 16.8 0.9 2.4 2 1 1 3 3 3 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SelR PF01641.18 RLN85888.1 - 0.065 13.3 0.2 1.2 9.2 0.1 2.7 2 0 0 2 2 2 0 SelR domain zf-ACC PF17848.1 RLN85888.1 - 0.22 11.7 1.8 0.47 10.6 0.0 2.6 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain SAND PF01342.21 RLN85888.1 - 0.39 10.4 1.7 1.9 8.2 0.1 2.7 3 0 0 3 3 3 0 SAND domain AKAP28 PF14469.6 RLN85889.1 - 3e-06 27.0 0.0 6.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 28 kDa A-kinase anchor EF-hand_9 PF14658.6 RLN85889.1 - 0.036 14.4 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain H_PPase PF03030.16 RLN85890.1 - 8.1e-239 794.6 31.7 9.2e-239 794.4 31.7 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase DUF3043 PF11241.8 RLN85891.1 - 1.4 8.9 7.3 5 7.1 7.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) PX PF00787.24 RLN85892.1 - 1.4e-11 44.4 0.0 4.7e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 PX domain CENP-B_dimeris PF09026.10 RLN85892.1 - 0.11 12.9 4.2 0.26 11.7 4.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Epimerase PF01370.21 RLN85893.1 - 3e-83 279.0 3.1 1e-38 133.2 0.0 4.2 3 1 1 4 4 4 4 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RLN85893.1 - 7.3e-75 252.4 3.3 5.4e-36 124.6 0.0 4.8 3 2 1 4 4 4 4 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 RLN85893.1 - 4.4e-32 111.2 2.2 1.5e-12 47.1 0.0 4.2 3 1 1 4 4 4 4 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 RLN85893.1 - 5.4e-19 68.4 1.5 3e-07 29.9 0.0 4.6 4 1 1 5 5 5 4 Male sterility protein Polysacc_synt_2 PF02719.15 RLN85893.1 - 1.1e-17 64.1 5.2 5.4e-08 32.3 0.0 5.7 3 2 1 4 4 4 3 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 RLN85893.1 - 2.2e-17 63.1 0.7 1.4e-08 34.2 0.0 3.3 3 1 1 4 4 4 2 RmlD substrate binding domain NAD_binding_10 PF13460.6 RLN85893.1 - 7.9e-10 38.9 0.0 0.38 10.6 0.0 4.7 4 1 1 5 5 5 4 NAD(P)H-binding PAC2 PF09754.9 RLN85893.1 - 7e-05 22.9 0.0 0.28 11.2 0.0 2.3 2 0 0 2 2 2 2 PAC2 family KR PF08659.10 RLN85893.1 - 0.0005 20.0 0.1 1 9.2 0.0 2.8 2 0 0 2 2 2 2 KR domain adh_short PF00106.25 RLN85893.1 - 0.0016 17.9 1.2 5.7 6.3 0.0 4.2 5 0 0 5 5 5 1 short chain dehydrogenase NmrA PF05368.13 RLN85893.1 - 0.016 14.8 1.4 7.1 6.1 0.0 3.6 3 1 1 4 4 4 0 NmrA-like family Sacchrp_dh_NADP PF03435.18 RLN85893.1 - 0.059 13.6 0.2 13 6.0 0.0 2.8 3 0 0 3 3 2 0 Saccharopine dehydrogenase NADP binding domain SpoVAD PF07451.11 RLN85893.1 - 0.073 11.8 0.0 8.4 5.0 0.0 2.4 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) 7tm_2 PF00002.24 RLN85894.1 - 2.6e-08 33.5 6.8 3.4e-08 33.1 6.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.17 RLN85894.1 - 1.5e-06 27.5 6.8 1.5e-06 27.5 6.8 2.0 1 1 1 2 2 2 2 Frizzled/Smoothened family membrane region ERGIC_N PF13850.6 RLN85894.1 - 0.0028 18.0 0.1 0.31 11.4 0.0 2.5 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Wzy_C PF04932.15 RLN85894.1 - 0.0056 16.3 1.2 0.19 11.3 0.0 2.2 1 1 1 2 2 2 1 O-Antigen ligase DUF679 PF05078.12 RLN85894.1 - 0.046 13.7 0.2 0.075 13.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF679) LigB PF02900.18 RLN85895.1 - 6.2e-32 110.8 0.0 8.6e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase KH_1 PF00013.29 RLN85896.1 - 3.7e-09 36.3 0.1 7.7e-09 35.3 0.1 1.5 1 0 0 1 1 1 1 KH domain ZFYVE21_C PF16696.5 RLN85896.1 - 0.088 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Zinc finger FYVE domain-containing protein 21 C-terminus CIAPIN1 PF05093.13 RLN85897.1 - 1.7e-15 57.4 12.7 6.5e-10 39.4 1.4 2.8 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DMRL_synthase PF00885.19 RLN85897.1 - 0.009 15.8 0.4 0.017 15.0 0.4 1.3 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase MORN PF02493.20 RLN85898.1 - 1.8e-85 276.0 145.9 1.4e-07 31.0 2.6 21.7 22 0 0 22 22 22 20 MORN repeat WW PF00397.26 RLN85898.1 - 0.0001 22.3 0.3 0.00039 20.4 0.3 2.1 1 0 0 1 1 1 1 WW domain FOXP-CC PF16159.5 RLN85898.1 - 0.056 14.1 2.8 0.2 12.3 2.8 1.9 1 0 0 1 1 1 0 FOXP coiled-coil domain DUF3211 PF11485.8 RLN85898.1 - 0.39 10.9 0.0 0.39 10.9 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3211) PhoD PF09423.10 RLN85899.1 - 5.4e-08 32.2 0.0 1.1e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 PhoD-like phosphatase CCDC53 PF10152.9 RLN85900.1 - 6.7e-74 247.4 57.8 4.8e-12 46.6 0.1 11.9 11 2 0 11 11 11 8 Subunit CCDC53 of WASH complex FH2 PF02181.23 RLN85900.1 - 4.3e-73 246.6 0.2 4.3e-73 246.6 0.2 1.5 2 0 0 2 2 2 1 Formin Homology 2 Domain CK2S PF15011.6 RLN85900.1 - 0.81 9.6 8.1 6.7 6.6 1.6 2.6 2 0 0 2 2 2 0 Casein Kinase 2 substrate DUF4404 PF14357.6 RLN85900.1 - 2.4 8.8 7.7 0.65 10.7 2.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) PAN_1 PF00024.26 RLN85901.1 - 8.8e-05 22.4 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 RLN85901.1 - 0.00096 19.0 0.1 0.0027 17.6 0.1 1.7 1 0 0 1 1 1 1 PAN domain Aldedh PF00171.22 RLN86017.1 - 2.5e-18 65.9 0.0 3.1e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ARL2_Bind_BART PF11527.8 RLN86018.1 - 1.4e-17 63.8 6.1 5.9e-17 61.8 6.1 1.8 1 1 0 1 1 1 1 The ARF-like 2 binding protein BART Pro_isomerase PF00160.21 RLN86019.1 - 1.6e-38 132.5 0.3 5.4e-38 130.7 0.3 1.7 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD C2 PF00168.30 RLN86020.1 - 0.0002 21.6 0.0 2.1 8.7 0.0 3.8 3 0 0 3 3 3 3 C2 domain W2 PF02020.18 RLN86021.1 - 1.2e-16 60.6 0.3 2.7e-16 59.5 0.3 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon DUF5401 PF17380.2 RLN86021.1 - 0.49 8.4 10.3 0.69 7.9 10.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) RR_TM4-6 PF06459.12 RLN86021.1 - 3.7 7.3 9.3 5.8 6.7 9.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 RLN86022.1 - 7.2e-67 226.0 34.8 1.9e-66 224.6 12.0 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter SPX PF03105.19 RLN86022.1 - 0.06 13.3 1.5 0.26 11.2 0.5 1.9 2 0 0 2 2 2 0 SPX domain SDA1 PF05285.12 RLN86022.1 - 8.9 5.6 10.3 15 4.9 10.3 1.3 1 0 0 1 1 1 0 SDA1 RNA_pol_Rpb1_5 PF04998.17 RLN86023.1 - 4.3e-66 223.1 0.0 7.5e-66 222.3 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_7 PF04990.12 RLN86023.1 - 1.2e-51 174.2 2.7 2.2e-51 173.4 2.7 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_R PF05001.13 RLN86023.1 - 8e-48 158.4 375.3 0.0013 19.0 12.4 21.2 15 2 0 20 20 20 18 RNA polymerase Rpb1 C-terminal repeat RNA_pol_Rpb1_6 PF04992.14 RLN86023.1 - 6.6e-27 94.6 0.1 1.3e-26 93.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 Dimer_Tnp_hAT PF05699.14 RLN86024.1 - 0.011 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Semialdhyde_dhC PF02774.18 RLN86025.1 - 4.6e-48 163.7 0.0 6.2e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 RLN86025.1 - 2e-25 89.6 0.0 4.2e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 RLN86025.1 - 0.0041 17.7 0.1 0.0096 16.5 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 RLN86025.1 - 0.13 11.8 0.2 0.29 10.6 0.1 1.7 2 0 0 2 2 2 0 NmrA-like family LRR_4 PF12799.7 RLN86026.1 - 4.7e-12 45.9 4.3 3.7e-05 24.0 0.2 3.1 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN86026.1 - 9.9e-08 31.6 5.3 0.0049 16.6 0.3 3.2 2 1 0 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 RLN86026.1 - 2.3e-07 30.5 1.8 5.5e-07 29.2 1.3 1.8 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 RLN86026.1 - 0.061 13.9 2.2 1.8e+02 3.3 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat DEAD PF00270.29 RLN86027.1 - 1.1e-50 171.8 0.0 1.4e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 RLN86027.1 - 0.0036 17.3 0.0 0.0088 16.1 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RLN86027.1 - 0.1 12.9 1.3 0.54 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 RLN86028.1 - 4e-11 42.4 41.8 4.5e-07 29.1 14.8 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RLN86028.1 - 2.9e-09 36.0 11.4 2.9e-09 36.0 11.4 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein BT1 PF03092.16 RLN86028.1 - 0.0069 14.7 0.2 0.0069 14.7 0.2 2.2 2 0 0 2 2 2 1 BT1 family MFS_2 PF13347.6 RLN86029.1 - 1.8e-10 39.9 11.9 1.8e-10 39.9 11.9 2.6 2 1 0 2 2 2 1 MFS/sugar transport protein HSP70 PF00012.20 RLN86030.1 - 3.8e-67 226.9 0.3 4.5e-67 226.6 0.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MFS_2 PF13347.6 RLN86031.1 - 1.3e-07 30.6 11.6 1.3e-07 30.6 11.6 3.2 2 2 1 3 3 3 2 MFS/sugar transport protein TMEM240 PF15207.6 RLN86031.1 - 0.0049 16.6 0.2 0.16 11.7 0.0 2.4 2 0 0 2 2 2 1 TMEM240 family MFS_2 PF13347.6 RLN86032.1 - 8.3e-14 51.0 6.2 8.3e-14 51.0 6.2 2.4 2 1 0 2 2 2 1 MFS/sugar transport protein BT1 PF03092.16 RLN86032.1 - 0.0031 15.8 0.1 0.0031 15.8 0.1 2.3 2 0 0 2 2 2 1 BT1 family TIG PF01833.24 RLN86105.1 - 2.4e-35 120.5 41.2 0.00051 20.1 0.0 20.6 21 1 0 21 21 21 11 IPT/TIG domain C2 PF00168.30 RLN86105.1 - 1.5e-09 38.0 0.0 1.7e-08 34.7 0.0 2.4 2 0 0 2 2 2 1 C2 domain EF-hand_8 PF13833.6 RLN86106.1 - 0.005 16.7 0.0 0.017 15.0 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair LRR_4 PF12799.7 RLN86107.1 - 1.3e-11 44.5 3.6 4.7e-05 23.7 0.1 3.1 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN86107.1 - 3.5e-11 42.9 0.5 1.9e-10 40.6 0.5 1.8 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 RLN86107.1 - 0.00011 21.9 2.7 0.01 15.6 1.5 2.5 2 0 0 2 2 2 2 Leucine rich repeat Afi1 PF07792.12 RLN86108.1 - 0.0054 17.2 0.1 0.0068 16.9 0.1 1.3 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking RNA_pol_Rpb2_7 PF04560.20 RLN86108.1 - 0.1 13.0 0.1 0.16 12.4 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 7 ubiquitin PF00240.23 RLN86110.1 - 1.7e-15 56.5 0.0 2.7e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 RLN86110.1 - 2.3e-08 33.8 0.3 2.3e-08 33.8 0.3 3.1 4 0 0 4 4 4 1 UBA/TS-N domain STI1 PF17830.1 RLN86110.1 - 3.4e-05 23.7 67.8 0.00077 19.4 10.0 5.5 2 2 2 4 4 4 3 STI1 domain LPD22 PF18834.1 RLN86110.1 - 0.0052 17.0 6.3 0.33 11.2 0.4 3.7 2 1 1 3 3 3 1 Large polyvalent protein associated domain 22 XPC-binding PF09280.11 RLN86110.1 - 0.0073 16.0 11.1 0.0073 16.0 11.1 6.0 2 2 3 5 5 5 2 XPC-binding domain ScsC_N PF18312.1 RLN86110.1 - 0.0096 15.7 6.5 3.8 7.4 0.3 4.5 4 0 0 4 4 4 2 Copper resistance protein ScsC N-terminal domain Rad60-SLD PF11976.8 RLN86110.1 - 0.025 14.4 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like BSD PF03909.17 RLN86110.1 - 0.17 11.9 9.9 0.69 10.0 0.4 3.9 3 1 0 3 3 3 0 BSD domain TACC_C PF05010.14 RLN86110.1 - 1.1 8.9 7.9 6.9 6.4 2.2 2.3 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal UPF0061 PF02696.14 RLN86111.1 - 1e-119 400.4 0.0 3.9e-119 398.5 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Ank_2 PF12796.7 RLN86112.1 - 2.2e-36 124.3 8.2 2.5e-07 31.2 0.2 4.0 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN86112.1 - 1.9e-21 76.2 19.1 5.5e-07 30.0 0.6 6.0 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN86112.1 - 2.6e-14 53.1 6.6 0.026 14.8 0.0 6.9 2 1 6 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN86112.1 - 1.3e-11 43.6 1.0 0.8 10.5 0.0 7.6 7 1 1 8 8 8 3 Ankyrin repeat DUF1843 PF08898.10 RLN86112.1 - 0.12 12.9 0.7 25 5.5 0.1 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) IQ PF00612.27 RLN86113.1 - 0.01 15.5 4.2 0.076 12.8 4.2 2.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Ank_4 PF13637.6 RLN86113.1 - 0.011 16.3 0.0 0.04 14.5 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN86113.1 - 0.023 15.3 0.1 0.06 13.9 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.30 RLN86113.1 - 0.11 13.0 0.0 0.3 11.6 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat RRM_1 PF00076.22 RLN86114.1 - 1.5e-12 47.2 0.0 8.4e-12 44.7 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hnRNP_Q_AcD PF18360.1 RLN86114.1 - 4.3e-12 45.8 0.1 9.2e-12 44.8 0.1 1.5 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain DUF1922 PF09082.10 RLN86114.1 - 5.6 7.3 19.3 5.1 7.5 0.4 5.4 4 2 2 6 6 6 0 Domain of unknown function (DUF1922) Ank_3 PF13606.6 RLN86115.1 - 2.1e-05 24.5 0.1 0.059 13.9 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 RLN86115.1 - 7.5e-05 23.2 0.0 0.023 15.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN86115.1 - 0.00011 22.7 0.3 0.02 15.5 0.2 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN86115.1 - 0.00017 21.8 0.1 0.04 14.2 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 RLN86115.1 - 0.077 13.5 0.1 0.95 10.0 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat FAM177 PF14774.6 RLN86118.1 - 2.8e-10 40.6 0.0 4.5e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 FAM177 family DUF2052 PF09747.9 RLN86118.1 - 0.0019 18.3 0.1 0.0029 17.8 0.1 1.2 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) DUF1682 PF07946.14 RLN86118.1 - 1.1 8.4 11.3 1.3 8.1 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) ABC_membrane PF00664.23 RLN86119.1 - 1.5e-40 139.6 3.8 6.9e-35 121.0 0.2 2.1 1 1 1 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN86119.1 - 1.1e-05 25.9 0.5 1.8e-05 25.3 0.5 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 RLN86119.1 - 0.0045 16.9 0.0 0.0085 16.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN86119.1 - 0.013 15.2 0.2 0.04 13.7 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3007 PF11460.8 RLN86119.1 - 0.018 15.3 2.7 0.41 10.9 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) Palm_thioest PF02089.15 RLN86120.1 - 0.0002 21.3 0.0 0.00042 20.2 0.0 1.7 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 RLN86120.1 - 0.0007 19.3 0.2 0.11 12.1 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF676 PF05057.14 RLN86120.1 - 0.091 12.3 0.0 0.56 9.7 0.0 2.2 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF2613 PF11021.8 RLN86121.1 - 0.42 10.8 4.8 1.4 9.1 4.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Palm_thioest PF02089.15 RLN86122.1 - 0.009 15.9 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 RLN86122.1 - 0.011 15.4 0.1 0.029 14.0 0.1 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 RLN86122.1 - 0.019 14.7 0.8 0.043 13.5 0.8 1.6 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 RLN86122.1 - 0.047 14.3 0.5 0.17 12.5 0.5 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.12 RLN86122.1 - 0.05 13.1 0.0 0.16 11.5 0.1 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 RLN86122.1 - 0.078 12.5 0.0 0.27 10.7 0.0 1.9 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 RLN86123.1 - 0.0079 15.9 0.7 0.064 12.9 0.1 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 RLN86123.1 - 0.031 14.1 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF900 PF05990.12 RLN86123.1 - 0.053 13.0 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 RLN86123.1 - 0.06 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 RLN86123.1 - 0.076 12.7 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 RLN86123.1 - 0.16 12.6 4.0 0.33 11.5 4.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Sod_Fe_C PF02777.18 RLN86124.1 - 8.9e-36 122.2 0.7 1.8e-35 121.2 0.1 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 RLN86124.1 - 8.7e-31 106.2 2.2 1.4e-30 105.6 2.2 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ChaB PF06150.12 RLN86124.1 - 0.085 13.4 0.9 0.085 13.4 0.9 1.9 2 0 0 2 2 2 0 ChaB dCMP_cyt_deam_1 PF00383.23 RLN86124.1 - 0.12 12.3 0.1 0.28 11.1 0.1 1.6 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Palm_thioest PF02089.15 RLN86125.1 - 0.00023 21.1 0.0 0.00039 20.4 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 RLN86125.1 - 0.0042 16.8 0.2 0.079 12.6 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF900 PF05990.12 RLN86125.1 - 0.0094 15.5 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 RLN86125.1 - 0.01 16.5 0.1 0.018 15.7 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 RLN86125.1 - 0.038 13.5 0.0 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 RLN86125.1 - 0.052 13.3 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 PGAP1-like protein Lipase_2 PF01674.18 RLN86125.1 - 0.21 11.1 0.9 7.2 6.1 0.0 2.7 3 0 0 3 3 3 0 Lipase (class 2) Ank_2 PF12796.7 RLN86126.1 - 8.1e-81 266.7 10.3 7.5e-18 64.9 0.5 7.8 4 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN86126.1 - 1.5e-62 207.2 10.1 1e-11 45.1 0.2 10.4 4 2 8 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 RLN86126.1 - 2.1e-53 176.5 19.9 5.9e-07 29.7 0.1 12.8 12 2 0 12 12 12 10 Ankyrin repeat Ank_3 PF13606.6 RLN86126.1 - 3.6e-52 168.2 15.1 0.00013 22.1 0.0 15.3 15 1 0 15 15 15 9 Ankyrin repeat Ank_5 PF13857.6 RLN86126.1 - 7.1e-50 166.4 28.5 1.5e-08 34.8 0.2 13.5 4 4 11 15 15 15 12 Ankyrin repeats (many copies) DUF4355 PF14265.6 RLN86126.1 - 0.063 13.5 0.5 21 5.4 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4355) CUE PF02845.16 RLN86126.1 - 7.4 6.4 5.2 55 3.6 0.0 4.0 5 0 0 5 5 5 0 CUE domain DUF2235 PF09994.9 RLN86127.1 - 0.00059 19.3 0.0 0.00094 18.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Palm_thioest PF02089.15 RLN86127.1 - 0.00073 19.4 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 RLN86127.1 - 0.0021 17.8 0.5 0.077 12.6 0.1 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN86127.1 - 0.0064 17.1 0.5 0.012 16.2 0.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 RLN86127.1 - 0.012 15.1 0.1 0.06 12.9 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 RLN86127.1 - 0.026 14.2 0.3 0.074 12.8 0.3 1.8 1 1 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 RLN86127.1 - 0.048 13.2 0.1 0.31 10.5 0.0 2.2 3 0 0 3 3 3 0 Putative serine esterase (DUF676) DUF915 PF06028.11 RLN86127.1 - 0.051 12.9 0.0 4.4 6.5 0.1 2.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 RLN86127.1 - 0.087 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 RLN86128.1 - 0.00078 19.2 0.1 0.086 12.5 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 RLN86128.1 - 0.0022 17.8 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 RLN86128.1 - 0.0032 17.0 0.0 0.17 11.4 0.0 2.8 3 0 0 3 3 3 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 RLN86128.1 - 0.0096 16.5 0.3 0.022 15.4 0.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2235 PF09994.9 RLN86128.1 - 0.047 13.0 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF900 PF05990.12 RLN86128.1 - 0.056 13.0 0.0 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 RLN86128.1 - 0.079 12.7 1.9 0.2 11.4 0.7 2.3 2 1 0 2 2 2 0 PGAP1-like protein Endotoxin_C2 PF18449.1 RLN86128.1 - 0.79 10.1 4.6 0.2 12.0 0.3 2.0 2 0 0 2 2 2 0 Delta endotoxin ABC2_membrane PF01061.24 RLN86129.1 - 1.3e-17 64.0 22.5 1.3e-17 64.0 22.5 1.8 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN86129.1 - 2.6e-07 30.4 0.0 2.6e-07 30.4 0.0 2.5 2 1 0 2 2 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 RLN86129.1 - 0.00033 19.9 17.7 0.00043 19.5 17.7 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein PDR_assoc PF08370.11 RLN86129.1 - 0.029 14.1 0.1 0.029 14.1 0.1 3.4 2 1 1 3 3 3 0 Plant PDR ABC transporter associated MIF4G PF02854.19 RLN86130.1 - 3.1e-18 66.2 0.0 4.4e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 MIF4G domain SLED PF12140.8 RLN86130.1 - 0.058 13.9 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 SLED domain F_actin_cap_B PF01115.17 RLN86131.1 - 7.9e-96 320.3 0.0 9.1e-96 320.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit RNA_pol_I_A49 PF06870.12 RLN86132.1 - 2.2e-84 283.6 1.4 2.6e-84 283.3 1.4 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor RWP-RK PF02042.15 RLN86132.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 RWP-RK domain AAA_16 PF13191.6 RLN86133.1 - 0.0045 17.4 0.1 0.0065 16.9 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain ATPase PF06745.13 RLN86133.1 - 0.0054 16.1 0.0 0.0066 15.8 0.0 1.1 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.6 RLN86133.1 - 0.03 14.6 0.0 0.04 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain HAUS4 PF14735.6 RLN86134.1 - 1.8e-09 37.7 6.1 9.2e-08 32.1 6.0 2.1 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 4 ABC2_membrane PF01061.24 RLN86135.1 - 2.5e-05 23.8 1.1 3e-05 23.6 0.5 1.4 2 0 0 2 2 2 1 ABC-2 type transporter Peptidase_S41 PF03572.18 RLN86182.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S41 DICT PF10069.9 RLN86182.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Sensory domain in DIguanylate Cyclases and Two-component system Vps16_N PF04841.13 RLN86185.1 - 2.5e-63 214.3 0.0 4.8e-63 213.3 0.0 1.4 1 1 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 RLN86185.1 - 2.8e-14 52.9 0.2 1.3e-13 50.7 0.1 2.0 2 0 0 2 2 2 1 Vps16, C-terminal region PBP_like_2 PF12849.7 RLN86185.1 - 0.0054 16.4 0.1 0.0093 15.7 0.1 1.3 1 0 0 1 1 1 1 PBP superfamily domain MFS_1 PF07690.16 RLN86186.1 - 5.3e-35 121.0 48.2 1.7e-31 109.4 23.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN86186.1 - 1e-33 116.9 16.9 1.4e-33 116.5 16.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter EcsB PF05975.12 RLN86186.1 - 1.4 7.7 13.9 0.59 8.9 8.4 2.4 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB ABC2_membrane PF01061.24 RLN86187.1 - 3.5e-15 56.0 17.2 3.5e-15 56.0 17.2 1.4 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN86187.1 - 1.6e-08 34.3 0.0 4.2e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 CDR ABC transporter Sensor PF13796.6 RLN86188.1 - 1.2e-07 31.9 70.0 2.4e-05 24.5 16.1 4.1 2 2 2 4 4 4 4 Putative sensor TFIIA PF03153.13 RLN86189.1 - 0.0025 17.9 18.5 0.0025 17.9 18.5 3.4 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Cullin_Nedd8 PF10557.9 RLN86189.1 - 0.054 13.5 1.8 0.21 11.6 0.3 3.0 2 0 0 2 2 2 0 Cullin protein neddylation domain RNA_pol_Rpb2_45 PF10385.9 RLN86189.1 - 0.21 11.9 0.8 1.8 8.9 0.0 2.6 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain Pdase_M17_N2 PF18295.1 RLN86189.1 - 0.52 10.6 4.7 0.4 10.9 1.3 2.6 2 0 0 2 2 2 0 M17 aminopeptidase N-terminal domain 2 DUF4457 PF14652.6 RLN86190.1 - 6e-94 315.0 0.0 2.4e-93 313.0 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4457) Pkinase PF00069.25 RLN86190.1 - 2.4e-52 177.9 5.0 2e-50 171.6 0.1 3.8 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN86190.1 - 1e-30 106.9 1.2 2.7e-24 85.8 1.0 3.5 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN86190.1 - 0.00066 18.6 0.0 0.0018 17.1 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase Arm PF00514.23 RLN86190.1 - 0.0026 17.8 6.0 3.2 7.9 0.0 5.0 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Kinase-like PF14531.6 RLN86190.1 - 0.0059 16.0 0.1 0.015 14.6 0.1 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN86190.1 - 0.018 14.4 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NAD_binding_4 PF07993.12 RLN86191.1 - 2.5e-43 148.1 0.2 6.5e-42 143.5 0.2 2.0 1 1 0 1 1 1 1 Male sterility protein CAP PF00188.26 RLN86192.1 - 5.4e-20 72.5 2.9 1.2e-19 71.4 2.9 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PAN_4 PF14295.6 RLN86192.1 - 1.7e-05 24.6 7.3 1.7e-05 24.6 7.3 2.2 2 0 0 2 2 2 1 PAN domain Ntox15 PF15604.6 RLN86192.1 - 0.5 10.5 2.4 5 7.2 2.3 2.0 1 1 0 1 1 1 0 Novel toxin 15 CAP PF00188.26 RLN86193.1 - 2.3e-19 70.5 2.8 4.5e-19 69.5 2.8 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PAN_4 PF14295.6 RLN86193.1 - 4.6e-07 29.6 6.4 4.6e-07 29.6 6.4 1.8 2 0 0 2 2 2 1 PAN domain Cue1_U7BR PF18499.1 RLN86195.1 - 0.071 13.2 1.0 0.16 12.0 1.0 1.5 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 Glyco_transf_43 PF03360.16 RLN86196.1 - 0.019 14.8 1.7 0.15 11.9 0.0 2.5 3 0 0 3 3 3 0 Glycosyltransferase family 43 Ank_2 PF12796.7 RLN86197.1 - 1.5e-24 86.4 4.7 4e-09 36.9 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN86197.1 - 1.1e-23 83.3 5.5 3.7e-08 33.8 0.1 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN86197.1 - 3.8e-20 71.7 15.5 0.0028 17.9 0.1 7.3 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN86197.1 - 3.1e-12 45.5 3.2 4.4 8.2 0.0 6.8 6 1 1 7 7 7 4 Ankyrin repeat DUF5049 PF16468.5 RLN86197.1 - 0.00044 20.1 0.0 36 4.4 0.0 4.9 3 1 2 5 5 5 0 Domain of unknown function (DUF5049) Ank PF00023.30 RLN86197.1 - 0.0015 18.9 1.9 45 4.7 0.0 5.5 2 1 2 4 4 4 0 Ankyrin repeat DUF3322 PF11795.8 RLN86197.1 - 0.015 15.3 1.9 0.6 10.1 0.0 3.3 2 2 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) UPF0489 PF12640.7 RLN86197.1 - 0.022 15.0 4.1 6.4 7.0 0.1 4.4 1 1 3 4 4 4 0 UPF0489 domain TruB_C_2 PF16198.5 RLN86197.1 - 0.12 12.6 0.1 0.32 11.2 0.1 1.7 2 0 0 2 2 2 0 tRNA pseudouridylate synthase B C-terminal domain DUF3280 PF11684.8 RLN86198.1 - 0.0017 18.8 1.5 0.0032 17.9 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2380) bZIP_1 PF00170.21 RLN86198.1 - 0.012 15.7 7.4 0.012 15.7 7.4 2.1 2 0 0 2 2 2 0 bZIP transcription factor SOTI PF17079.5 RLN86198.1 - 0.083 13.3 0.3 0.15 12.5 0.1 1.5 1 1 0 1 1 1 0 Male-specific protein scotti UPF0449 PF15136.6 RLN86198.1 - 7.6 7.1 10.1 3.9 8.0 3.7 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Paz_1 PF18349.1 RLN86199.1 - 0.092 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 PAZ domain Presenilin PF01080.17 RLN86203.1 - 1.4e-100 336.8 1.3 1.4e-99 333.6 1.3 2.1 1 1 0 1 1 1 1 Presenilin Androgen_recep PF02166.16 RLN86203.1 - 0.0034 16.3 23.1 0.0066 15.3 23.1 1.4 1 0 0 1 1 1 1 Androgen receptor SPX PF03105.19 RLN86203.1 - 0.0046 16.9 6.5 0.0046 16.9 6.5 2.0 2 0 0 2 2 2 1 SPX domain CDC45 PF02724.14 RLN86203.1 - 0.022 13.1 2.9 0.03 12.6 2.9 1.3 1 0 0 1 1 1 0 CDC45-like protein PRP3 PF08572.10 RLN86203.1 - 0.038 13.7 13.1 0.64 9.7 4.6 2.2 2 0 0 2 2 2 0 pre-mRNA processing factor 3 (PRP3) CBP_BcsG PF11658.8 RLN86203.1 - 0.074 11.4 0.1 0.12 10.8 0.1 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Spt20 PF12090.8 RLN86203.1 - 0.18 11.4 23.9 0.38 10.3 23.9 1.6 1 0 0 1 1 1 0 Spt20 family Peptidase_S64 PF08192.11 RLN86203.1 - 0.23 9.9 7.3 0.33 9.4 7.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 TFIIA PF03153.13 RLN86203.1 - 0.26 11.3 22.0 0.51 10.3 22.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.7 RLN86203.1 - 0.27 9.3 5.8 0.39 8.8 5.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.9 RLN86203.1 - 0.38 9.0 14.5 0.55 8.4 14.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 G0-G1_switch_2 PF15103.6 RLN86203.1 - 0.58 10.6 4.9 0.14 12.6 1.0 2.0 2 0 0 2 2 1 0 G0/G1 switch protein 2 CPSF100_C PF13299.6 RLN86203.1 - 1 9.5 7.8 2.5 8.3 7.8 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Plasmodium_Vir PF05795.11 RLN86203.1 - 1.2 8.5 6.4 1.3 8.4 4.3 1.9 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Ndc1_Nup PF09531.10 RLN86203.1 - 1.2 7.8 11.6 1.5 7.5 9.0 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup GREB1 PF15782.5 RLN86203.1 - 1.5 5.8 12.9 2.1 5.4 12.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TERB2 PF15101.6 RLN86203.1 - 1.6 8.8 12.1 3.4 7.7 12.1 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Macoilin PF09726.9 RLN86203.1 - 3.6 6.0 10.1 7.6 5.0 10.1 1.4 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 RLN86203.1 - 3.8 6.3 12.0 0.16 10.8 6.6 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain Band_3_cyto PF07565.13 RLN86203.1 - 4.3 7.1 8.8 10 5.8 8.8 1.6 2 0 0 2 2 2 0 Band 3 cytoplasmic domain NPR3 PF03666.13 RLN86203.1 - 4.6 5.9 10.6 9.2 4.9 10.6 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2070 PF09843.9 RLN86203.1 - 6.5 4.9 8.0 13 4.0 8.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4231 PF14015.6 RLN86203.1 - 7.9 7.0 6.6 10 6.6 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Pyr_redox_dim PF02852.22 RLN86204.1 - 5.1e-27 94.3 0.1 8.1e-27 93.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.14 RLN86204.1 - 1.9e-21 76.6 0.1 4.8e-21 75.2 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RLN86204.1 - 0.066 11.9 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Anp1 PF03452.14 RLN86206.1 - 1.3e-42 146.1 0.3 2.6e-42 145.1 0.3 1.4 1 1 0 1 1 1 1 Anp1 APAF1_C PF17908.1 RLN86206.1 - 0.087 12.8 0.2 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 APAF-1 helical domain PHO4 PF01384.20 RLN86207.1 - 1.9e-19 69.9 7.0 2.1e-19 69.8 7.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family ABC2_membrane PF01061.24 RLN86208.1 - 5.6e-20 71.7 19.7 5.6e-20 71.7 19.7 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 RLN86208.1 - 2.1e-08 33.7 16.1 2.7e-08 33.3 16.1 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein Colicin_V PF02674.16 RLN86208.1 - 0.15 12.0 9.4 1.5 8.8 4.8 2.5 2 1 0 2 2 2 0 Colicin V production protein ABC2_membrane_2 PF12679.7 RLN86208.1 - 0.4 9.9 9.8 0.56 9.4 9.8 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF2070 PF09843.9 RLN86208.1 - 7.8 4.7 9.6 9 4.5 9.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Pkinase_Tyr PF07714.17 RLN86209.1 - 1.3e-43 149.1 0.0 1.4e-38 132.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN86209.1 - 6.9e-35 120.7 0.0 4.9e-26 91.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain zf-ribbon_3 PF13248.6 RLN86209.1 - 6.1e-05 22.3 1.7 0.00012 21.4 1.7 1.4 1 0 0 1 1 1 1 zinc-ribbon domain APH PF01636.23 RLN86209.1 - 0.0012 18.9 0.0 0.31 10.9 0.0 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family DZR PF12773.7 RLN86209.1 - 0.0014 18.6 0.5 0.0014 18.6 0.5 1.8 2 0 0 2 2 2 1 Double zinc ribbon Kdo PF06293.14 RLN86209.1 - 0.003 17.0 0.0 0.037 13.4 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN86209.1 - 0.013 14.8 0.0 0.27 10.5 0.0 2.1 2 0 0 2 2 2 0 Kinase-like zinc_ribbon_15 PF17032.5 RLN86209.1 - 0.019 15.7 0.7 0.046 14.5 0.7 1.7 1 0 0 1 1 1 0 zinc-ribbon family Haspin_kinase PF12330.8 RLN86209.1 - 0.075 12.0 0.0 3 6.7 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain UPF0547 PF10571.9 RLN86209.1 - 0.09 12.9 6.1 0.17 12.0 6.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 RIO1 PF01163.22 RLN86209.1 - 0.11 12.0 0.0 13 5.3 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.11 RLN86209.1 - 0.13 11.3 0.0 10 5.0 0.0 2.4 2 0 0 2 2 2 0 Seadornavirus VP7 AceK PF06315.11 RLN86209.1 - 0.25 9.8 0.0 0.4 9.1 0.0 1.2 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) WW PF00397.26 RLN86210.1 - 1.6e-08 34.5 0.2 4.9e-08 32.9 0.1 1.9 2 0 0 2 2 2 1 WW domain PDZ PF00595.24 RLN86210.1 - 3.7e-05 24.0 0.0 9.1e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RLN86210.1 - 0.00027 21.2 0.0 0.00059 20.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Macoilin PF09726.9 RLN86210.1 - 0.29 9.7 3.5 0.45 9.0 3.5 1.3 1 0 0 1 1 1 0 Macoilin family zf-C2H2_4 PF13894.6 RLN86211.1 - 0.049 14.5 12.4 10 7.3 2.0 4.2 3 0 0 3 3 3 0 C2H2-type zinc finger FYDLN_acid PF09538.10 RLN86211.1 - 0.077 13.7 0.3 0.077 13.7 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DZR PF12773.7 RLN86211.1 - 0.28 11.2 1.8 0.66 10.0 1.8 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-Di19 PF05605.12 RLN86211.1 - 0.72 10.2 5.3 0.63 10.4 0.9 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Pox_Ag35 PF03286.14 RLN86212.1 - 0.014 15.2 5.6 0.014 15.2 5.6 1.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Exonuc_VII_S PF02609.16 RLN86212.1 - 0.052 13.6 0.1 3 8.0 0.0 2.3 2 0 0 2 2 2 0 Exonuclease VII small subunit SnoaL PF07366.12 RLN86212.1 - 0.069 12.9 0.0 0.31 10.8 0.0 2.1 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase Nop14 PF04147.12 RLN86212.1 - 0.2 9.9 7.1 0.25 9.5 7.1 1.1 1 0 0 1 1 1 0 Nop14-like family TSC22 PF01166.18 RLN86212.1 - 0.24 11.7 1.1 4.4 7.7 0.2 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family Cwf_Cwc_15 PF04889.12 RLN86212.1 - 0.44 10.2 8.4 0.67 9.6 8.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 RLN86212.1 - 0.46 8.7 3.9 0.58 8.4 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein FYDLN_acid PF09538.10 RLN86212.1 - 1.2 9.9 12.2 2.2 9.0 12.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) NOA36 PF06524.12 RLN86212.1 - 1.4 8.1 13.0 2.1 7.6 13.0 1.1 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 RLN86212.1 - 1.6 8.2 8.7 2.7 7.5 8.7 1.2 1 0 0 1 1 1 0 PPP4R2 DUF3295 PF11702.8 RLN86212.1 - 1.7 7.9 7.9 2.8 7.2 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DNA_pol_phi PF04931.13 RLN86212.1 - 2.8 5.9 14.7 4 5.4 14.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 RLN86212.1 - 3.6 7.2 6.8 7 6.3 6.8 1.4 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 RLN86212.1 - 6.9 6.7 8.6 13 5.8 8.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal BRE1 PF08647.11 RLN86213.1 - 0.0022 18.0 3.1 0.0022 18.0 3.1 15.1 8 4 6 15 15 15 3 BRE1 E3 ubiquitin ligase FYVE PF01363.21 RLN86214.1 - 3.3e-15 56.0 10.4 5.6e-15 55.2 10.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger Ank_5 PF13857.6 RLN86214.1 - 0.0009 19.5 0.2 0.0033 17.7 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN86214.1 - 0.11 13.1 0.0 0.22 12.2 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) FYVE_2 PF02318.16 RLN86214.1 - 1 9.6 4.9 2.1 8.6 4.9 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger RXT2_N PF08595.11 RLN86214.1 - 2.4 8.2 7.4 5.4 7.0 7.4 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal DZR PF12773.7 RLN86214.1 - 7 6.8 8.9 46 4.1 9.0 2.1 1 1 0 1 1 1 0 Double zinc ribbon TPR_2 PF07719.17 RLN86215.1 - 0.026 14.6 8.8 12 6.3 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Mating_N PF12731.7 RLN86215.1 - 0.036 14.2 0.2 6.2 7.0 0.0 3.8 3 0 0 3 3 3 0 Mating-type protein beta 1 SNAP PF14938.6 RLN86215.1 - 0.047 13.1 3.1 0.075 12.4 0.0 2.5 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP Coilin_N PF15862.5 RLN86215.1 - 0.074 12.9 0.6 0.16 11.7 0.6 1.5 1 0 0 1 1 1 0 Coilin N-terminus TPR_7 PF13176.6 RLN86215.1 - 0.72 10.0 7.3 12 6.2 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Myb_DNA-bind_4 PF13837.6 RLN86216.1 - 0.00016 22.0 0.0 0.00035 20.9 0.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Ldl_recept_b PF00058.17 RLN86216.1 - 0.02 15.4 8.0 3.4 8.2 0.1 5.4 5 0 0 5 5 5 0 Low-density lipoprotein receptor repeat class B TIG PF01833.24 RLN86216.1 - 0.025 14.6 0.3 0.062 13.4 0.3 1.6 1 0 0 1 1 1 0 IPT/TIG domain CAP PF00188.26 RLN86218.1 - 1.9e-21 77.2 3.3 2.3e-21 77.0 3.3 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 RLN86219.1 - 1.8e-22 80.5 0.6 2.3e-22 80.1 0.6 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MtmB PF05369.12 RLN86219.1 - 0.1 11.4 0.1 0.12 11.2 0.1 1.1 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB Glyco_hydro_3_C PF01915.22 RLN86220.1 - 7e-66 222.1 0.0 1.1e-45 156.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 RLN86220.1 - 6.6e-36 124.3 0.0 2.3e-35 122.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 RLN86220.1 - 1.5e-15 57.0 0.1 6e-08 32.7 0.0 2.9 3 0 0 3 3 3 2 Fibronectin type III-like domain T6SS-SciN PF12790.7 RLN86220.1 - 0.003 17.3 0.1 2.8 7.7 0.0 2.4 2 0 0 2 2 2 2 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 DUF2584 PF10763.9 RLN86220.1 - 0.15 12.2 0.0 18 5.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2584) Anoctamin PF04547.12 RLN86222.1 - 0.024 13.5 0.0 0.027 13.3 0.0 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Kelch_3 PF13415.6 RLN86223.1 - 5.6e-18 64.8 0.1 0.00067 19.9 0.0 4.9 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_4 PF13418.6 RLN86223.1 - 5.4e-16 58.3 0.4 0.0011 18.9 0.0 4.9 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 RLN86223.1 - 1.7e-13 49.9 0.2 0.011 15.3 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 RLN86223.1 - 8.9e-12 44.7 5.4 0.0039 17.1 0.1 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 RLN86223.1 - 2.4e-10 40.0 1.2 0.0046 16.9 0.1 4.8 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 RLN86223.1 - 2.5e-08 33.9 3.2 0.29 11.5 0.0 4.9 5 0 0 5 5 4 3 Kelch motif fn3 PF00041.21 RLN86223.1 - 5e-07 30.0 0.0 2.9e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 Fibronectin type III domain zf-C3HC4_2 PF13923.6 RLN86223.1 - 2.5e-06 27.2 8.0 6.6e-06 25.9 8.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN86223.1 - 5e-05 23.1 7.6 0.00014 21.6 7.6 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 RLN86223.1 - 5.3e-05 23.5 7.7 0.00016 22.0 7.7 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RLN86223.1 - 9e-05 22.3 6.7 0.00021 21.1 6.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN86223.1 - 0.00013 21.7 7.9 0.00033 20.4 7.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Sec23_Sec24 PF04810.15 RLN86223.1 - 0.0013 18.7 2.4 0.071 13.2 0.0 2.4 1 1 1 2 2 2 1 Sec23/Sec24 zinc finger zf-RING_UBOX PF13445.6 RLN86223.1 - 0.0044 17.0 8.0 0.012 15.6 8.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 RLN86223.1 - 0.0072 16.4 3.5 0.016 15.3 3.5 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 RLN86223.1 - 0.0081 16.3 9.3 0.018 15.2 9.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 RLN86223.1 - 0.02 14.8 6.9 0.068 13.1 6.9 1.9 1 1 0 1 1 1 0 zinc-RING finger domain TSP_1 PF00090.19 RLN86223.1 - 0.096 12.9 6.1 0.24 11.6 6.1 1.7 1 0 0 1 1 1 0 Thrombospondin type 1 domain TerY_C PF15616.6 RLN86223.1 - 0.27 11.3 1.7 0.69 10.0 1.7 1.6 1 0 0 1 1 1 0 TerY-C metal binding domain zf-CCCH_4 PF18044.1 RLN86224.1 - 1.6e-14 53.3 40.1 1.8e-08 34.0 3.3 4.0 4 0 0 4 4 4 3 CCCH-type zinc finger zf_CCCH_4 PF18345.1 RLN86224.1 - 1.4e-12 47.2 32.1 2.1e-06 27.6 6.2 4.0 3 1 0 3 3 3 3 Zinc finger domain Torus PF16131.5 RLN86224.1 - 6.8e-10 39.6 12.9 1.6e-05 25.5 0.6 3.4 2 1 1 3 3 3 3 Torus domain zf-CCCH PF00642.24 RLN86224.1 - 2.5e-09 36.8 27.9 1e-05 25.3 1.5 3.8 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.6 RLN86224.1 - 2.3e-07 31.0 9.2 2.3e-07 31.0 9.2 2.6 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 RLN86224.1 - 7.2e-06 25.8 7.1 1.9e-05 24.5 7.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN86224.1 - 1.1e-05 25.2 9.3 1.7e-05 24.7 7.2 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RLN86224.1 - 3.1e-05 23.9 1.7 3.1e-05 23.9 1.7 2.2 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RLN86224.1 - 3.9e-05 23.4 6.1 0.00017 21.4 6.1 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 RLN86224.1 - 0.00066 19.4 7.1 0.0022 17.7 7.1 1.9 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 RLN86224.1 - 0.0025 17.6 12.1 0.0026 17.6 6.4 2.8 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-CCCH_2 PF14608.6 RLN86224.1 - 0.0062 17.0 1.9 0.0062 17.0 1.9 3.9 3 0 0 3 3 3 1 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 RLN86224.1 - 0.007 16.6 10.7 0.039 14.2 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger containing family zf-C3HC4_4 PF15227.6 RLN86224.1 - 0.014 15.5 5.2 0.014 15.5 5.2 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 RLN86224.1 - 0.21 11.3 9.2 0.51 10.1 9.2 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 RLN86224.1 - 0.22 11.4 9.7 0.87 9.5 9.7 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) LRR_8 PF13855.6 RLN86225.1 - 5.4e-22 77.3 13.5 1.4e-08 34.3 5.3 3.7 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 RLN86225.1 - 3.4e-14 52.7 12.4 0.00063 20.1 0.0 5.3 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN86225.1 - 0.00021 21.4 7.8 8.8 7.3 0.0 7.3 6 2 0 6 6 6 1 Leucine Rich Repeat PAP2 PF01569.21 RLN86226.1 - 7.2e-36 123.0 3.4 3.1e-23 82.0 1.1 2.6 2 0 0 2 2 2 2 PAP2 superfamily PAP2_3 PF14378.6 RLN86226.1 - 7.8e-07 29.0 7.0 3.7e-06 26.8 2.0 2.9 3 1 0 3 3 3 2 PAP2 superfamily LRR_4 PF12799.7 RLN86227.1 - 4.2e-09 36.5 4.9 0.0004 20.7 0.5 3.6 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN86227.1 - 9.6e-09 34.9 11.3 4.2e-05 23.2 3.2 3.0 1 1 2 3 3 3 3 Leucine rich repeat zf-C3H1 PF10650.9 RLN86227.1 - 9.4e-08 31.6 3.3 2.1e-07 30.6 3.3 1.6 1 0 0 1 1 1 1 Putative zinc-finger domain NRDE-2 PF08424.10 RLN86227.1 - 2.8e-06 26.7 1.6 2.8e-06 26.7 1.6 2.2 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference LRR_9 PF14580.6 RLN86227.1 - 0.13 11.8 0.1 0.31 10.5 0.1 1.7 1 0 0 1 1 1 0 Leucine-rich repeat PG_binding_1 PF01471.18 RLN86227.1 - 0.19 11.9 1.4 46 4.3 0.0 3.9 4 0 0 4 4 4 0 Putative peptidoglycan binding domain LRR_1 PF00560.33 RLN86227.1 - 0.36 11.6 3.2 1.8e+02 3.3 0.2 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat DUF1825 PF08855.10 RLN86229.1 - 3 7.8 10.2 2.1 8.3 2.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1825) Myotub-related PF06602.14 RLN86230.1 - 1.1e-72 244.9 0.0 4.9e-61 206.6 0.0 2.1 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 RLN86230.1 - 0.02 14.8 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 RLN86230.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Drf_FH1 PF06346.12 RLN86231.1 - 0.1 12.3 27.2 0.18 11.5 27.2 1.3 1 0 0 1 1 1 0 Formin Homology Region 1 Mob_synth_C PF06463.13 RLN86231.1 - 0.24 11.4 2.5 0.27 11.1 0.2 2.2 2 1 0 2 2 2 0 Molybdenum Cofactor Synthesis C zf-U1 PF06220.12 RLN86231.1 - 0.52 10.1 10.9 3.4 7.5 2.8 3.1 3 1 0 3 3 3 0 U1 zinc finger PRKCSH-like PF12999.7 RLN86231.1 - 1 9.2 3.9 2 8.2 3.9 1.4 1 0 0 1 1 1 0 Glucosidase II beta subunit-like Ribosomal_L14 PF00238.19 RLN86232.1 - 6.2e-36 123.2 0.0 7.4e-36 122.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ank_2 PF12796.7 RLN86233.1 - 1.5e-19 70.3 1.0 1.4e-10 41.7 0.3 4.0 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN86233.1 - 3.5e-15 56.2 0.1 3e-12 46.8 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN86233.1 - 4.8e-14 51.1 0.8 0.0015 18.8 0.0 4.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 RLN86233.1 - 1.1e-13 51.1 2.4 2.6e-06 27.6 0.7 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN86233.1 - 2e-12 46.9 3.4 6e-05 23.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat FYVE PF01363.21 RLN86233.1 - 7.5e-06 26.0 6.4 1.5e-05 25.0 6.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger DZR PF12773.7 RLN86233.1 - 1.3 9.1 9.5 41 4.3 0.0 2.5 2 0 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 RLN86233.1 - 8.9 6.4 11.5 5.8 7.0 6.3 2.4 2 0 0 2 2 2 0 zinc-ribbons Myb_DNA-binding PF00249.31 RLN86234.1 - 7.8e-30 102.8 1.6 4.6e-14 52.3 0.3 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN86234.1 - 8e-19 67.7 0.5 1.4e-13 50.9 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain LRR_4 PF12799.7 RLN86234.1 - 3.7e-06 27.2 4.6 1.7 9.1 0.1 4.9 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RLN86234.1 - 0.0018 18.1 0.5 21 5.5 0.0 5.1 5 0 0 5 5 5 1 Leucine Rich repeat LRR_8 PF13855.6 RLN86234.1 - 0.041 13.6 4.0 0.082 12.7 0.2 3.1 4 0 0 4 4 4 0 Leucine rich repeat Exo70 PF03081.15 RLN86234.1 - 0.24 10.4 2.2 2.4 7.1 0.0 2.4 2 1 0 2 2 2 0 Exo70 exocyst complex subunit LRR_1 PF00560.33 RLN86234.1 - 1.9 9.3 3.6 79 4.4 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich Repeat Ras PF00071.22 RLN86236.1 - 6.1e-30 104.0 0.0 7.3e-30 103.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN86236.1 - 3.3e-12 46.7 0.0 3.8e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 RLN86236.1 - 2.6e-05 24.3 0.0 3.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RLN86236.1 - 0.026 14.9 0.0 0.03 14.7 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 RLN86236.1 - 0.027 14.4 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Hexapep PF00132.24 RLN86237.1 - 1.1e-16 59.7 12.1 2.8e-06 26.8 0.3 4.3 4 0 0 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 RLN86237.1 - 0.00047 19.8 15.7 0.0014 18.4 0.5 4.0 4 1 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 RLN86237.1 - 0.067 12.1 0.2 0.12 11.3 0.2 1.4 1 1 0 1 1 1 0 L-fucokinase DEAD PF00270.29 RLN86239.1 - 1.2e-40 139.1 0.2 1e-39 136.1 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN86239.1 - 2e-25 89.3 0.1 2.7e-23 82.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN86239.1 - 0.0033 17.5 0.0 0.013 15.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RLN86239.1 - 0.042 14.2 0.2 0.16 12.3 0.0 2.1 2 2 0 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 RLN86239.1 - 0.059 12.2 0.1 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer DUF5377 PF17347.2 RLN86239.1 - 0.1 13.0 0.0 0.32 11.4 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5377) PIN_9 PF18477.1 RLN86239.1 - 0.33 11.3 1.7 2.9 8.3 0.0 2.8 2 1 1 3 3 3 0 PIN like domain FHA PF00498.26 RLN86241.1 - 2.6e-06 27.7 0.0 6.2e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RLN86241.1 - 0.025 14.9 0.0 0.044 14.1 0.0 1.4 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain DUF4781 PF16013.5 RLN86241.1 - 0.57 8.9 1.8 0.79 8.5 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Inositol_P PF00459.25 RLN86242.1 - 1.6e-63 214.8 0.4 2.3e-63 214.3 0.4 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family EXS PF03124.14 RLN86242.1 - 3.4e-47 161.4 20.7 5e-44 151.0 20.7 2.1 1 1 0 1 1 1 1 EXS family FBPase_glpX PF03320.13 RLN86242.1 - 0.031 13.1 0.2 0.24 10.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded Clathrin PF00637.20 RLN86243.1 - 9.3e-16 58.0 6.0 6.8e-15 55.2 0.5 2.7 1 1 0 2 2 2 2 Region in Clathrin and VPS WD40 PF00400.32 RLN86243.1 - 0.00018 22.2 0.2 0.0015 19.3 0.0 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat Vps39_1 PF10366.9 RLN86243.1 - 0.02 15.1 3.2 0.073 13.4 0.0 3.2 2 2 2 4 4 4 0 Vacuolar sorting protein 39 domain 1 DUF465 PF04325.13 RLN86243.1 - 0.086 12.9 1.8 7.8 6.6 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF465) S4 PF01479.25 RLN86244.1 - 1.5e-09 37.4 0.7 1.5e-09 37.4 0.7 2.2 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 RLN86244.1 - 9.2e-06 26.5 2.0 2.1e-05 25.4 0.8 2.2 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain DUF4776 PF16003.5 RLN86244.1 - 0.17 10.8 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) MRP-S23 PF10484.9 RLN86245.1 - 0.0014 18.9 0.3 0.0055 17.0 0.3 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 2OG-FeII_Oxy_3 PF13640.6 RLN86247.1 - 1.9e-05 25.5 0.0 6.9e-05 23.7 0.0 2.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2205 PF10224.9 RLN86248.1 - 0.00088 19.2 19.2 0.24 11.4 1.5 3.6 3 0 0 3 3 3 3 Short coiled-coil protein TFIID-18kDa PF02269.16 RLN86248.1 - 0.0057 16.6 0.6 2.8 8.0 0.1 2.8 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit DUF5320 PF17253.2 RLN86248.1 - 0.089 13.9 11.8 2.7 9.1 0.2 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5320) LRS4 PF10422.9 RLN86248.1 - 0.11 12.1 23.3 0.076 12.6 1.2 3.3 3 0 0 3 3 3 0 Monopolin complex subunit LRS4 Lipase_GDSL_2 PF13472.6 RLN86248.1 - 0.19 12.1 1.2 5 7.5 0.0 2.9 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase family CLZ PF16526.5 RLN86248.1 - 0.29 11.5 14.0 1.3 9.5 0.7 3.6 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels 5_3_exonuc_N PF02739.16 RLN86248.1 - 0.53 10.2 4.0 34 4.3 0.0 3.3 3 0 0 3 3 3 0 5'-3' exonuclease, N-terminal resolvase-like domain DUF3135 PF11333.8 RLN86248.1 - 0.64 10.3 18.4 0.083 13.2 0.7 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3135) DUF2508 PF10704.9 RLN86248.1 - 0.98 9.6 13.0 9.7 6.5 0.6 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) DUF2258 PF10015.9 RLN86248.1 - 1.6 8.9 5.5 17 5.6 0.2 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2258) Takusan PF04822.13 RLN86248.1 - 2.3 8.2 14.8 0.49 10.3 0.8 3.7 3 0 0 3 3 3 0 Takusan COMM_domain PF07258.14 RLN86248.1 - 2.3 8.4 9.0 4.5 7.5 0.6 3.4 3 0 0 3 3 3 0 COMM domain Cob_adeno_trans PF01923.18 RLN86248.1 - 3.2 7.9 15.6 9.6 6.3 3.2 3.4 3 0 0 3 3 3 0 Cobalamin adenosyltransferase DUF4436 PF14494.6 RLN86248.1 - 4.7 6.4 10.1 7 5.8 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4436) SLX9 PF15341.6 RLN86248.1 - 5 7.5 20.5 2.4 8.5 3.8 3.6 3 0 0 3 3 3 0 Ribosome biogenesis protein SLX9 DUF3138 PF11336.8 RLN86248.1 - 6.6 5.2 21.0 1.1 7.8 3.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3138) Peptidase_S10 PF00450.22 RLN86249.1 - 1.2e-118 397.1 0.0 1.5e-118 396.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase 2OG-FeII_Oxy_3 PF13640.6 RLN86250.1 - 0.0003 21.6 0.1 0.00098 20.0 0.1 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Peptidase_S10 PF00450.22 RLN86251.1 - 1.4e-25 90.6 0.0 1.5e-25 90.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF1968 PF09291.10 RLN86251.1 - 0.031 14.3 0.1 0.042 13.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1968) Peptidase_S10 PF00450.22 RLN86252.1 - 2.7e-119 399.3 0.9 3.5e-119 398.9 0.9 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase GRA6 PF05084.13 RLN86252.1 - 0.0056 16.7 0.7 0.97 9.3 0.1 2.3 2 0 0 2 2 2 2 Granule antigen protein (GRA6) DUF4307 PF14155.6 RLN86252.1 - 0.039 13.8 1.6 1.5 8.7 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) DUF4330 PF14221.6 RLN86252.1 - 0.75 10.0 3.6 12 6.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) Plus-3 PF03126.18 RLN86254.1 - 2.4e-14 53.8 0.0 2.4e-14 53.8 0.0 2.8 3 0 0 3 3 3 1 Plus-3 domain Mannosyl_trans3 PF11051.8 RLN86255.1 - 6.2e-34 117.6 0.0 1.8e-25 89.8 0.0 2.5 2 1 0 2 2 2 2 Mannosyltransferase putative PIF1 PF05970.14 RLN86255.1 - 0.11 11.7 0.0 15 4.6 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase LTXXQ PF07813.12 RLN86255.1 - 0.35 11.6 2.6 0.87 10.3 2.6 1.6 1 0 0 1 1 1 0 LTXXQ motif family protein XRCC1_N PF01834.16 RLN86256.1 - 0.045 13.8 0.0 0.08 12.9 0.0 1.4 1 1 0 1 1 1 0 XRCC1 N terminal domain UPF0054 PF02130.17 RLN86257.1 - 3.7e-23 81.7 0.0 4.4e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 malic PF00390.19 RLN86258.1 - 1.4e-42 145.5 0.0 2e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Mito_carr PF00153.27 RLN86259.1 - 9.4e-19 67.1 10.1 2.5e-09 36.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF659 PF04937.15 RLN86260.1 - 2.9e-21 75.9 0.0 4.8e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 RLN86260.1 - 3e-08 33.3 0.0 7.7e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF1477 PF07346.11 RLN86260.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1477) PSD4 PF07631.11 RLN86260.1 - 0.13 12.8 1.1 0.41 11.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) OrfB_Zn_ribbon PF07282.11 RLN86261.1 - 1.5e-17 63.2 2.1 1.5e-17 63.2 2.1 1.8 2 0 0 2 2 2 1 Putative transposase DNA-binding domain HTH_OrfB_IS605 PF12323.8 RLN86261.1 - 1.1e-07 31.3 0.4 7.3e-07 28.6 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain C1_2 PF03107.16 RLN86261.1 - 0.0085 16.4 4.8 0.0094 16.3 2.6 2.1 2 0 0 2 2 2 1 C1 domain DUF2608 PF11019.8 RLN86261.1 - 0.016 14.7 0.3 0.024 14.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) OrfB_IS605 PF01385.19 RLN86261.1 - 0.045 14.0 0.3 0.045 14.0 0.3 2.1 2 1 0 2 2 2 0 Probable transposase DUF1364 PF07102.12 RLN86261.1 - 0.058 13.3 1.3 0.13 12.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1364) C1_1 PF00130.22 RLN86261.1 - 0.059 13.3 0.9 0.17 11.8 0.4 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Choline_transpo PF04515.12 RLN86263.1 - 1.7e-71 241.1 38.4 1.7e-71 241.1 38.4 2.3 1 1 1 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.13 RLN86263.1 - 0.39 11.4 1.6 0.76 10.4 1.6 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF677 PF05055.12 RLN86263.1 - 4.5 6.1 4.3 44 2.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF677) C2 PF00168.30 RLN86264.1 - 0.044 14.1 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 C2 domain ABC_tran_CTD PF16326.5 RLN86266.1 - 0.0019 18.4 4.0 1.5 9.1 0.4 3.4 3 0 0 3 3 3 2 ABC transporter C-terminal domain FlxA PF14282.6 RLN86266.1 - 0.0056 16.6 6.5 0.98 9.4 2.1 2.9 2 1 0 2 2 2 2 FlxA-like protein PspA_IM30 PF04012.12 RLN86266.1 - 0.013 15.0 8.2 0.059 12.9 1.3 2.5 2 0 0 2 2 2 0 PspA/IM30 family DUF5082 PF16888.5 RLN86266.1 - 0.046 14.0 2.5 3.7 7.9 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Csm1_N PF18504.1 RLN86266.1 - 0.047 14.0 3.8 8.1 6.9 0.2 3.2 3 0 0 3 3 2 0 Csm1 N-terminal domain Ribosomal_L29 PF00831.23 RLN86266.1 - 0.066 13.2 3.1 0.43 10.6 0.4 2.8 2 0 0 2 2 2 0 Ribosomal L29 protein DivIC PF04977.15 RLN86266.1 - 0.14 12.0 6.4 4 7.3 0.1 3.1 3 0 0 3 3 3 0 Septum formation initiator DUF3573 PF12097.8 RLN86266.1 - 0.32 9.8 0.5 7.8 5.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) CENP-F_leu_zip PF10473.9 RLN86266.1 - 0.33 11.0 5.4 7.9 6.5 1.0 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.12 RLN86266.1 - 0.37 11.4 6.9 5.6 7.7 0.2 3.3 3 0 0 3 3 3 0 SlyX YlqD PF11068.8 RLN86266.1 - 0.44 10.9 6.7 6.3 7.2 0.8 2.4 2 0 0 2 2 2 0 YlqD protein ZapB PF06005.12 RLN86266.1 - 0.67 10.4 13.1 1.7 9.1 1.2 3.4 2 1 0 2 2 2 0 Cell division protein ZapB DUF4349 PF14257.6 RLN86266.1 - 1.5 8.2 10.3 1.4 8.3 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) Integrase_DNA PF02920.15 RLN86266.1 - 2.8 7.7 6.0 0.53 10.0 1.1 2.3 2 0 0 2 2 2 0 DNA binding domain of tn916 integrase bZIP_1 PF00170.21 RLN86266.1 - 4 7.6 15.6 7.1 6.8 4.4 2.8 2 0 0 2 2 2 0 bZIP transcription factor MbeD_MobD PF04899.12 RLN86266.1 - 4.5 7.5 7.8 1.8 8.8 1.0 2.8 3 0 0 3 3 2 0 MbeD/MobD like DUF4407 PF14362.6 RLN86266.1 - 5.5 6.3 8.7 9.1 5.5 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Nnf1 PF03980.14 RLN86266.1 - 5.5 7.4 9.9 0.34 11.3 1.4 3.0 3 0 0 3 3 3 0 Nnf1 DUF4140 PF13600.6 RLN86266.1 - 8.2 6.9 11.8 2.8 8.4 0.2 3.1 4 0 0 4 4 2 0 N-terminal domain of unknown function (DUF4140) Val_tRNA-synt_C PF10458.9 RLN86266.1 - 8.9 6.7 8.7 22 5.4 0.1 3.1 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm bZIP_2 PF07716.15 RLN86267.1 - 2.6e-05 24.2 8.4 2.6e-05 24.2 8.4 2.4 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 RLN86267.1 - 0.21 11.7 14.2 0.029 14.5 9.5 1.9 2 0 0 2 2 2 0 bZIP transcription factor bZIP_1 PF00170.21 RLN86268.1 - 0.11 12.6 4.2 0.21 11.7 4.2 1.4 1 0 0 1 1 1 0 bZIP transcription factor DUF1640 PF07798.11 RLN86271.1 - 0.018 15.1 0.1 0.027 14.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Mt_ATP-synt_B PF05405.14 RLN86271.1 - 0.26 10.9 2.8 0.41 10.3 2.8 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF4164 PF13747.6 RLN86271.1 - 1.2 9.4 10.0 1.9 8.8 6.1 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) FTCD_C PF04961.12 RLN86275.1 - 0.025 14.3 0.8 0.048 13.4 0.8 1.4 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase CCDC24 PF15669.5 RLN86275.1 - 2 8.3 4.7 4.3 7.1 4.7 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family NUDE_C PF04880.13 RLN86275.1 - 8.3 6.9 13.1 16 6.0 13.1 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Cpn60_TCP1 PF00118.24 RLN86278.1 - 1.1e-141 472.8 13.2 1.2e-141 472.7 13.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family His_Phos_1 PF00300.22 RLN86279.1 - 1.4e-51 175.0 0.3 1.7e-51 174.7 0.3 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TGS PF02824.21 RLN86280.1 - 4.8e-08 32.9 0.0 8.9e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 TGS domain MTHFR PF02219.17 RLN86281.1 - 3e-92 309.0 0.0 4.7e-92 308.3 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF1712 PF08217.11 RLN86281.1 - 0.00063 18.4 0.0 0.0018 16.9 0.0 1.7 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1712) APG6_N PF17675.1 RLN86281.1 - 0.19 12.3 5.6 0.1 13.1 1.5 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region CLTH PF10607.9 RLN86283.1 - 1.2e-08 35.0 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 RLN86283.1 - 3.3e-06 27.2 0.0 3.7e-05 23.8 0.0 2.6 2 0 0 2 2 2 1 SPRY domain SUV3_C PF12513.8 RLN86284.1 - 5.6e-13 48.6 0.5 1.4e-12 47.3 0.5 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 RLN86284.1 - 6.6e-12 45.1 0.7 4.1e-11 42.6 0.2 2.3 2 0 0 2 2 2 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 RLN86284.1 - 4.7e-11 43.0 0.0 1.1e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_N PF18114.1 RLN86284.1 - 0.029 14.5 0.0 0.069 13.3 0.0 1.6 1 0 0 1 1 1 0 Suv3 helical N-terminal domain UTP25 PF06862.12 RLN86285.1 - 1.6e-143 478.9 0.1 2.3e-143 478.4 0.1 1.2 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 3-PAP PF12578.8 RLN86285.1 - 0.075 12.8 0.3 5.1 6.8 0.0 3.3 3 1 0 3 3 3 0 Myotubularin-associated protein UPRTase PF14681.6 RLN86286.1 - 1.8e-10 40.7 0.0 2.6e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HTH_23 PF13384.6 RLN86286.1 - 0.12 12.2 0.4 0.23 11.3 0.4 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Exo_endo_phos PF03372.23 RLN86287.1 - 8.6e-05 22.2 0.0 0.0006 19.4 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Claudin_3 PF06653.11 RLN86287.1 - 0.013 15.5 5.3 0.26 11.2 1.5 2.3 2 0 0 2 2 2 0 Tight junction protein, Claudin-like Claudin_2 PF13903.6 RLN86287.1 - 3.1 7.5 13.0 11 5.7 12.4 2.0 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction MCU PF04678.13 RLN86288.1 - 2.7e-25 89.5 0.4 5.5e-25 88.5 0.4 1.5 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Prefoldin_2 PF01920.20 RLN86288.1 - 0.035 14.0 3.2 0.22 11.5 1.0 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF3287 PF11690.8 RLN86288.1 - 0.036 13.8 1.2 0.57 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Snapin_Pallidin PF14712.6 RLN86288.1 - 0.049 14.0 3.9 0.1 13.0 1.1 2.4 2 0 0 2 2 2 0 Snapin/Pallidin Unstab_antitox PF09720.10 RLN86288.1 - 0.35 11.0 5.1 0.9 9.6 0.3 3.0 3 0 0 3 3 3 0 Putative addiction module component V-ATPase_G PF03179.15 RLN86289.1 - 5.2e-19 68.7 11.1 1.3e-18 67.4 11.1 1.6 1 1 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 RLN86289.1 - 0.0027 17.2 10.5 0.0029 17.1 9.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3552) NAM-associated PF14303.6 RLN86289.1 - 1.5 9.5 8.9 2.4 8.8 8.9 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain LRR_8 PF13855.6 RLN86290.1 - 0.0076 16.0 3.9 0.49 10.2 1.4 3.6 1 1 3 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 RLN86290.1 - 0.066 13.7 4.2 5.1 7.7 0.0 3.4 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) GSHPx PF00255.19 RLN86291.1 - 2.7e-26 91.3 0.0 4.2e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase Na_trans_assoc PF06512.13 RLN86291.1 - 0.00012 22.4 4.1 0.00017 22.0 4.1 1.2 1 0 0 1 1 1 1 Sodium ion transport-associated DNA_pol_phi PF04931.13 RLN86291.1 - 0.019 13.1 35.5 0.023 12.8 35.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi SAPS PF04499.15 RLN86291.1 - 0.051 12.4 1.3 0.046 12.5 1.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 RLN86291.1 - 0.28 9.3 27.3 0.34 9.1 27.3 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 RLN86291.1 - 0.5 9.7 30.3 0.68 9.3 30.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RNA_pol_Rpc4 PF05132.14 RLN86291.1 - 1 9.8 6.4 1.8 9.0 6.4 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Mpp10 PF04006.12 RLN86291.1 - 1.1 7.7 24.9 1.3 7.4 24.9 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 RLN86291.1 - 6.3 6.0 23.3 7.9 5.7 23.3 1.1 1 0 0 1 1 1 0 BUD22 LRR_8 PF13855.6 RLN86292.1 - 6.3e-42 141.2 38.1 8e-09 35.1 2.3 8.2 4 3 5 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 RLN86292.1 - 1e-29 102.0 23.5 0.00014 22.1 0.1 8.8 6 2 3 9 9 9 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN86292.1 - 1.1e-08 34.7 9.4 0.0018 17.8 0.3 4.5 2 2 3 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 RLN86292.1 - 0.00014 22.0 36.5 5 8.1 0.0 12.9 13 3 0 13 13 13 2 Leucine Rich Repeat LRR_6 PF13516.6 RLN86292.1 - 1.9 8.8 30.7 3.4 8.0 0.0 9.6 11 0 0 11 11 11 0 Leucine Rich repeat Ax_dynein_light PF10211.9 RLN86293.1 - 5.6e-86 287.3 12.9 6.6e-86 287.0 12.9 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain APG6_N PF17675.1 RLN86293.1 - 0.0083 16.6 11.3 0.0083 16.6 11.3 1.6 2 0 0 2 2 2 1 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 RLN86293.1 - 0.024 14.8 12.8 0.024 14.8 12.8 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 U79_P34 PF03064.16 RLN86293.1 - 0.19 11.1 3.7 0.23 10.8 3.0 1.4 2 0 0 2 2 2 0 HSV U79 / HCMV P34 UPF0242 PF06785.11 RLN86293.1 - 0.22 11.6 7.8 0.44 10.6 7.8 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 RLN86293.1 - 0.4 11.1 3.7 6 7.4 0.4 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) PRKG1_interact PF15898.5 RLN86293.1 - 2.3 9.2 14.9 0.6 11.0 11.9 1.6 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain ZapB PF06005.12 RLN86293.1 - 5.3 7.6 16.6 32 5.1 16.6 2.2 1 1 0 1 1 1 0 Cell division protein ZapB Spc24 PF08286.11 RLN86293.1 - 5.6 7.3 10.5 20 5.5 10.5 2.0 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Hist_deacetyl PF00850.19 RLN86294.1 - 3.4e-78 263.2 0.2 4.5e-78 262.8 0.2 1.1 1 0 0 1 1 1 1 Histone deacetylase domain F-box-like PF12937.7 RLN86294.1 - 0.0022 17.8 0.9 0.0058 16.5 0.9 1.7 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 RLN86294.1 - 0.069 12.7 0.5 0.15 11.7 0.5 1.5 1 0 0 1 1 1 0 F-box ADH_N PF08240.12 RLN86295.1 - 1.3e-25 89.4 0.9 2.5e-25 88.5 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN86295.1 - 2.2e-23 82.7 0.1 3.8e-23 81.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 RLN86295.1 - 0.00021 20.6 0.3 0.00036 19.9 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 RLN86295.1 - 0.0046 16.3 0.1 0.0073 15.7 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 RLN86295.1 - 0.015 16.3 0.0 0.032 15.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 RLN86295.1 - 0.034 13.7 0.1 0.055 13.0 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ubiquitin PF00240.23 RLN86295.1 - 0.047 13.5 0.2 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin family Glyco_hydro_3_C PF01915.22 RLN86296.1 - 5.4e-50 170.2 0.0 7.9e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 RLN86296.1 - 9.1e-31 107.4 0.0 1.4e-30 106.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 RLN86296.1 - 0.00017 21.7 0.0 0.00038 20.5 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Sep15_SelM PF08806.11 RLN86297.1 - 1.4e-18 66.8 0.0 1.3e-14 54.1 0.0 2.7 2 0 0 2 2 2 2 Sep15/SelM redox domain DUF3381 PF11861.8 RLN86297.1 - 5 6.9 12.1 3.1 7.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) ARGLU PF15346.6 RLN86298.1 - 0.011 15.7 3.6 0.011 15.7 3.6 1.8 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 BLM_N PF16202.5 RLN86299.1 - 0.15 11.1 4.7 0.23 10.6 4.7 1.2 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein Borrelia_P83 PF05262.11 RLN86299.1 - 6.4 5.1 17.4 7.6 4.9 17.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein SOBP PF15279.6 RLN86299.1 - 7.3 7.1 17.0 12 6.4 17.0 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein UPRTase PF14681.6 RLN86300.1 - 1.6e-25 89.8 0.1 3.2e-25 88.8 0.1 1.4 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 RLN86300.1 - 0.0044 16.6 0.1 0.0075 15.8 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain HTH_23 PF13384.6 RLN86300.1 - 0.073 12.9 0.2 0.21 11.5 0.2 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.15 RLN86300.1 - 0.078 13.1 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase RRM_1 PF00076.22 RLN86301.1 - 5.6e-14 51.7 0.1 6.5e-09 35.5 0.0 2.1 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN86301.1 - 0.0031 17.6 0.0 0.0046 17.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif Limkain-b1 PF11608.8 RLN86301.1 - 0.0057 16.7 0.8 0.077 13.1 0.0 2.6 2 1 0 2 2 2 1 Limkain b1 MCM PF00493.23 RLN86303.1 - 1e-98 328.9 0.0 1.5e-98 328.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RLN86303.1 - 1.9e-35 121.5 0.1 3.1e-35 120.8 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RLN86303.1 - 4.1e-22 78.4 0.5 1.1e-21 77.0 0.1 1.9 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 RLN86303.1 - 5.7e-16 59.0 1.3 1e-15 58.2 0.1 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 RLN86303.1 - 1e-08 34.8 0.1 6.6e-07 28.9 0.0 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI MCM2_N PF12619.8 RLN86303.1 - 1.2e-08 35.3 31.8 1.2e-08 35.3 31.8 4.0 3 1 2 5 5 3 1 Mini-chromosome maintenance protein 2 AAA_5 PF07728.14 RLN86303.1 - 6.2e-06 26.3 0.0 1.9e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 RLN86303.1 - 6.6e-05 22.8 0.0 0.01 15.7 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RLN86303.1 - 0.002 17.9 0.0 0.0071 16.1 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 RLN86303.1 - 0.031 14.7 0.0 0.1 13.1 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-Sec23_Sec24 PF04810.15 RLN86303.1 - 0.038 14.0 0.6 0.072 13.2 0.6 1.4 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger AAA_30 PF13604.6 RLN86303.1 - 0.05 13.3 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain zf-TFIIB PF13453.6 RLN86303.1 - 0.08 12.3 1.2 0.16 11.3 1.2 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger AAA_lid_2 PF17863.1 RLN86303.1 - 9.6 6.1 12.5 0.15 11.9 0.4 3.7 5 0 0 5 5 5 0 AAA lid domain KBP_C PF12309.8 RLN86304.1 - 1.4e-78 265.0 0.0 2.3e-78 264.2 0.0 1.4 1 0 0 1 1 1 1 KIF-1 binding protein C terminal TPR_7 PF13176.6 RLN86304.1 - 3.7 7.8 15.0 8.3 6.7 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TINF2_N PF14973.6 RLN86305.1 - 0.0092 16.3 1.7 0.03 14.7 1.7 1.9 1 0 0 1 1 1 1 TERF1-interacting nuclear factor 2 N-terminus TolA_bind_tri PF16331.5 RLN86305.1 - 0.029 14.4 0.9 0.029 14.4 0.9 4.1 3 1 1 4 4 4 0 TolA binding protein trimerisation Prominin PF05478.11 RLN86305.1 - 0.77 7.6 7.0 0.14 10.1 3.7 1.3 2 0 0 2 2 2 0 Prominin Spc7 PF08317.11 RLN86305.1 - 1.4 7.7 10.4 0.24 10.3 5.9 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1690 PF07956.11 RLN86305.1 - 1.9 8.9 0.0 1.9 8.9 0.0 3.6 3 1 1 4 4 4 0 Protein of Unknown function (DUF1690) Seryl_tRNA_N PF02403.22 RLN86305.1 - 2.5 8.4 6.9 37 4.6 3.1 2.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2730 PF10805.8 RLN86305.1 - 3.5 7.8 8.3 31 4.7 0.2 4.5 3 2 1 4 4 4 0 Protein of unknown function (DUF2730) DsbD_2 PF13386.6 RLN86306.1 - 0.0014 18.6 0.6 0.002 18.1 0.6 1.1 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region COPI_assoc PF08507.10 RLN86306.1 - 0.0082 16.2 1.3 0.014 15.5 1.3 1.3 1 0 0 1 1 1 1 COPI associated protein FAM176 PF14851.6 RLN86306.1 - 0.26 10.9 0.8 0.51 10.0 0.5 1.6 2 0 0 2 2 2 0 FAM176 family DIOX_N PF14226.6 RLN86307.1 - 6.9e-26 91.3 0.0 1.2e-25 90.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 RLN86307.1 - 6.6e-25 87.5 0.0 1.4e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Vps26 PF03643.15 RLN86308.1 - 1.4e-97 326.0 0.0 1.7e-97 325.7 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 TPR_12 PF13424.6 RLN86310.1 - 1.7e-15 57.1 10.7 3.4e-06 27.3 0.5 4.6 2 1 1 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 RLN86310.1 - 1e-13 50.4 5.3 0.0018 18.1 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 RLN86310.1 - 1.4e-12 47.0 5.3 2.4e-05 24.1 1.3 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN86310.1 - 2.1e-12 46.2 4.7 0.007 16.4 0.2 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 RLN86310.1 - 1.3e-10 40.6 5.2 0.00079 19.4 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN86310.1 - 3.2e-05 23.6 3.9 0.003 17.5 0.2 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat SNAP PF14938.6 RLN86310.1 - 0.0028 17.2 0.3 0.0082 15.6 0.3 1.8 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_16 PF13432.6 RLN86310.1 - 0.012 16.3 0.4 0.074 13.7 0.4 2.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_15 PF13429.6 RLN86310.1 - 0.014 14.6 1.8 0.052 12.8 0.3 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN86310.1 - 0.015 16.1 3.1 3.4 8.7 0.1 4.3 3 1 1 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN86310.1 - 1.2 9.5 5.5 1.5 9.1 3.1 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Proteasome PF00227.26 RLN86311.1 - 5.7e-48 162.9 0.0 6.8e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit AAA PF00004.29 RLN86312.1 - 5e-31 107.9 0.0 6.3e-21 75.2 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RLN86312.1 - 1.5e-06 28.3 0.0 0.029 14.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RLN86312.1 - 4.3e-06 27.0 1.5 0.00056 20.2 0.1 3.4 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 RLN86312.1 - 5.4e-06 26.9 0.3 0.0022 18.4 0.1 3.5 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 RLN86312.1 - 0.00026 20.8 0.1 0.39 10.5 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 RLN86312.1 - 0.0015 18.9 1.6 0.26 11.6 0.2 3.9 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.6 RLN86312.1 - 0.0017 18.4 0.0 0.0048 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 RLN86312.1 - 0.0018 18.1 0.0 1.6 8.5 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein Rad17 PF03215.15 RLN86312.1 - 0.0021 18.0 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_lid_3 PF17862.1 RLN86312.1 - 0.0022 17.8 1.4 0.22 11.4 0.4 3.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_33 PF13671.6 RLN86312.1 - 0.0024 18.1 0.0 0.15 12.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RLN86312.1 - 0.0029 18.1 0.0 3 8.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RLN86312.1 - 0.0039 16.7 0.1 0.11 12.0 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 RLN86312.1 - 0.009 15.7 1.2 2 8.1 0.1 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain RNA_helicase PF00910.22 RLN86312.1 - 0.01 16.2 0.0 1.7 9.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Zot PF05707.12 RLN86312.1 - 0.013 15.1 0.1 0.05 13.2 0.0 1.9 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) AAA_24 PF13479.6 RLN86312.1 - 0.018 14.8 0.1 0.59 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 RLN86312.1 - 0.021 14.9 0.0 0.15 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 RLN86312.1 - 0.035 14.4 0.1 2.5 8.3 0.0 3.8 3 0 0 3 3 2 0 AAA domain TIP49 PF06068.13 RLN86312.1 - 0.038 13.2 0.2 8 5.5 0.1 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain NACHT PF05729.12 RLN86312.1 - 0.049 13.6 0.1 1.4 8.8 0.0 3.3 3 0 0 3 3 3 0 NACHT domain SRP54 PF00448.22 RLN86312.1 - 0.051 13.2 0.1 0.16 11.5 0.1 1.9 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CbiA PF01656.23 RLN86312.1 - 0.085 12.9 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 RLN86312.1 - 0.1 12.1 0.3 1.8 8.1 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 RLN86312.1 - 0.11 12.2 1.0 0.56 9.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 RLN86312.1 - 0.12 11.5 0.0 0.34 9.9 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 RLN86312.1 - 0.12 12.1 0.7 11 5.9 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain GntR PF00392.21 RLN86312.1 - 0.15 11.7 0.2 7.5 6.3 0.0 3.2 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family Mg_chelatase PF01078.21 RLN86312.1 - 0.42 10.0 1.9 5.3 6.4 0.3 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI eIF-1a PF01176.19 RLN86313.1 - 1e-20 73.3 0.4 1.6e-20 72.7 0.4 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 E1-E2_ATPase PF00122.20 RLN86314.1 - 0.056 13.0 6.6 0.078 12.5 0.0 4.0 4 0 0 4 4 4 0 E1-E2 ATPase TMEM51 PF15345.6 RLN86314.1 - 2.9 7.7 5.8 1.3 8.8 0.8 2.7 3 0 0 3 3 3 0 Transmembrane protein 51 Aldo_ket_red PF00248.21 RLN86315.1 - 6.6e-70 235.6 0.0 7.5e-70 235.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AAA PF00004.29 RLN86316.1 - 8.1e-41 139.5 0.0 1.6e-40 138.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RLN86316.1 - 4.7e-11 42.3 0.0 2.1e-10 40.3 0.0 2.2 2 0 0 2 2 1 1 AAA+ lid domain RuvB_N PF05496.12 RLN86316.1 - 3.2e-09 36.7 0.0 5.9e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RLN86316.1 - 2.1e-05 24.7 1.2 0.0002 21.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RLN86316.1 - 5e-05 23.6 0.1 0.13 12.5 0.0 2.8 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 RLN86316.1 - 5.1e-05 23.3 0.1 0.00048 20.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Nucleolin_bd PF16725.5 RLN86316.1 - 0.00021 20.9 0.1 0.00054 19.6 0.1 1.7 1 0 0 1 1 1 1 Nucleolin binding domain TIP49 PF06068.13 RLN86316.1 - 0.0006 19.1 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 RLN86316.1 - 0.0011 18.5 3.3 0.36 10.4 0.1 3.3 2 1 1 3 3 3 2 AAA domain AAA_2 PF07724.14 RLN86316.1 - 0.0015 18.6 0.0 0.0069 16.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 RLN86316.1 - 0.0042 17.5 0.1 0.0042 17.5 0.1 3.8 3 2 1 4 4 4 1 AAA ATPase domain Mg_chelatase PF01078.21 RLN86316.1 - 0.0052 16.2 0.0 0.014 14.8 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 RLN86316.1 - 0.0055 16.5 0.1 0.014 15.1 0.0 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 RLN86316.1 - 0.01 16.2 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 RLN86316.1 - 0.012 15.6 1.2 0.076 12.9 0.0 2.7 2 2 1 3 3 3 0 NACHT domain Vps4_C PF09336.10 RLN86316.1 - 0.013 15.5 0.6 0.047 13.7 0.1 2.2 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain ABC_tran PF00005.27 RLN86316.1 - 0.026 15.0 0.0 0.22 12.0 0.0 2.2 1 1 1 2 2 2 0 ABC transporter AAA_18 PF13238.6 RLN86316.1 - 0.062 13.8 0.0 0.26 11.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RLN86316.1 - 0.069 13.4 0.9 0.23 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 RLN86316.1 - 0.09 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 RLN86316.1 - 0.096 12.9 5.6 1.3 9.2 0.0 3.3 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain CPT PF07931.12 RLN86316.1 - 0.1 12.5 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Sigma54_activat PF00158.26 RLN86316.1 - 0.13 12.0 0.0 0.46 10.2 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain GSH_synth_ATP PF03917.17 RLN86317.1 - 9.6e-119 396.5 0.0 1.2e-118 396.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 RLN86317.1 - 1.8e-31 108.6 0.0 7.4e-31 106.6 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic glutathione synthase Hap4_Hap_bind PF10297.9 RLN86317.1 - 0.28 11.3 5.2 0.62 10.3 5.2 1.5 1 0 0 1 1 1 0 Minimal binding motif of Hap4 for binding to Hap2/3/5 Sugar_tr PF00083.24 RLN86318.1 - 2.3e-74 250.9 11.8 2.8e-74 250.6 11.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN86318.1 - 2.6e-09 36.5 21.3 2.8e-06 26.5 16.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3481 PF11980.8 RLN86318.1 - 6.4 6.6 10.0 0.066 12.9 1.2 2.3 3 0 0 3 3 3 0 C-terminal domain of neuropilin glycoprotein PYC_OADA PF02436.18 RLN86319.1 - 0.098 12.4 0.2 0.11 12.2 0.2 1.0 1 0 0 1 1 1 0 Conserved carboxylase domain LicD PF04991.13 RLN86320.1 - 2.6e-11 44.1 0.0 1.9e-07 31.5 0.0 2.1 2 0 0 2 2 2 2 LicD family RPAP1_C PF08620.10 RLN86321.1 - 3.5e-23 81.5 1.8 5.6e-23 80.8 0.3 2.2 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 RLN86321.1 - 1.2e-14 53.7 1.1 1.2e-14 53.7 1.1 2.3 2 0 0 2 2 2 1 RPAP1-like, N-terminal SWI-SNF_Ssr4 PF08549.10 RLN86321.1 - 0.033 12.9 9.2 0.058 12.0 9.2 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) PhyH PF05721.13 RLN86322.1 - 0.021 15.1 0.1 0.065 13.5 0.1 2.0 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) PX PF00787.24 RLN86322.1 - 0.092 12.7 0.2 1.2 9.1 0.0 2.6 2 1 0 2 2 2 0 PX domain G6PD_C PF02781.16 RLN86323.1 - 4.6e-25 88.4 0.0 2.7e-24 85.9 0.0 1.9 1 1 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 RLN86323.1 - 5e-08 33.8 0.0 1.7e-07 32.1 0.0 1.8 1 1 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Arm PF00514.23 RLN86324.1 - 1.8e-13 50.0 1.4 0.00065 19.7 0.0 4.1 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN86324.1 - 0.00073 19.9 3.2 0.063 13.7 0.3 2.7 1 1 2 3 3 3 3 HEAT repeats Atx10homo_assoc PF09759.9 RLN86324.1 - 0.019 15.0 0.1 2 8.5 0.1 2.7 1 1 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 RLN86324.1 - 0.44 11.3 4.1 24 6.0 0.2 4.2 4 3 0 4 4 4 0 PBS lyase HEAT-like repeat Myosin_head PF00063.21 RLN86325.1 - 5.3e-10 38.2 0.0 7.1e-10 37.8 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 RLN86325.1 - 0.0032 17.7 0.0 0.0041 17.4 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RLN86325.1 - 0.025 14.9 0.0 0.025 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 RLN86325.1 - 0.03 14.0 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain PIF1 PF05970.14 RLN86325.1 - 0.056 12.6 0.2 0.22 10.7 0.0 1.7 1 1 0 2 2 2 0 PIF1-like helicase AAA_30 PF13604.6 RLN86325.1 - 0.057 13.1 0.0 0.066 12.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RLN86325.1 - 0.11 13.1 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 RLN86325.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase TsaE PF02367.17 RLN86325.1 - 0.13 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 RLN86325.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 RLN86325.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 RLN86325.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 RLN86325.1 - 0.15 12.5 0.1 0.31 11.4 0.0 1.6 2 0 0 2 2 2 0 RNA helicase AAA_6 PF12774.7 RLN86325.1 - 0.16 10.9 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region PlyB_C PF18684.1 RLN86326.1 - 0.025 14.3 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Pleurotolysin B C-terminal domain UPF0203 PF05254.12 RLN86326.1 - 0.22 11.8 1.3 0.37 11.1 1.3 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) PWI PF01480.17 RLN86332.1 - 0.21 11.9 0.0 0.47 10.8 0.0 1.5 1 0 0 1 1 1 0 PWI domain HTH_17 PF12728.7 RLN86333.1 - 5.9e-05 23.2 0.1 0.062 13.5 0.1 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_32 PF13565.6 RLN86333.1 - 0.00015 22.3 0.3 0.028 15.0 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 RLN86333.1 - 0.0013 18.4 0.7 0.035 13.9 0.1 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_6 PF01418.17 RLN86333.1 - 0.011 15.7 0.0 7.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_11 PF08279.12 RLN86333.1 - 0.02 14.8 0.5 1.4 8.9 0.1 2.4 2 0 0 2 2 2 0 HTH domain HTH_28 PF13518.6 RLN86333.1 - 0.021 14.9 1.1 0.11 12.7 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_38 PF13936.6 RLN86333.1 - 0.11 12.3 2.0 4.1 7.3 0.2 3.1 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 RLN86333.1 - 0.12 11.8 0.4 0.57 9.6 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Nup88 PF10168.9 RLN86334.1 - 1.4e-17 62.9 6.1 7.6e-07 27.3 5.3 4.3 4 0 0 4 4 4 4 Nuclear pore component ThiF PF00899.21 RLN86335.1 - 6.7e-25 87.9 0.1 2e-24 86.3 0.1 1.6 1 1 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 RLN86335.1 - 0.12 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PHD PF00628.29 RLN86336.1 - 0.0019 18.0 5.0 0.0019 18.0 5.0 3.4 3 1 0 3 3 3 1 PHD-finger Pinin_SDK_N PF04697.13 RLN86337.1 - 0.064 13.9 0.5 0.13 12.9 0.4 1.6 1 1 0 1 1 1 0 pinin/SDK conserved region Ank_2 PF12796.7 RLN86338.1 - 1.1e-30 106.0 16.5 1.3e-07 32.0 0.0 4.6 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN86338.1 - 1.6e-20 73.2 2.2 0.00015 22.3 0.0 4.9 3 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN86338.1 - 3.9e-20 69.8 8.3 0.022 15.2 0.0 7.5 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 RLN86338.1 - 8.9e-17 60.9 12.8 0.0027 18.0 0.1 6.9 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 RLN86338.1 - 3.7e-14 52.4 15.2 0.014 15.8 0.1 6.5 7 0 0 7 7 7 5 Ankyrin repeat EF_assoc_1 PF08355.12 RLN86340.1 - 0.02 14.5 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 EF hand associated Med31 PF05669.12 RLN86340.1 - 0.088 12.8 4.2 0.89 9.6 2.2 2.3 2 0 0 2 2 2 0 SOH1 Kelch_3 PF13415.6 RLN86341.1 - 4.6e-40 135.2 13.0 2.2e-08 34.2 0.1 7.8 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.6 RLN86341.1 - 2.4e-33 113.9 7.5 2.3e-05 24.3 0.2 6.6 5 2 1 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 RLN86341.1 - 3e-33 113.1 0.3 1e-05 25.0 0.1 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 RLN86341.1 - 8.6e-28 95.2 2.3 5e-05 23.1 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 RLN86341.1 - 7.4e-27 92.7 0.9 5.1e-06 26.6 0.0 6.3 4 2 2 6 6 6 5 Kelch motif Kelch_5 PF13854.6 RLN86341.1 - 9e-25 86.2 0.2 3.8e-06 26.8 0.0 5.6 5 0 0 5 5 5 5 Kelch motif BTB PF00651.31 RLN86341.1 - 1.9e-18 66.7 3.1 5e-16 58.9 0.1 2.7 3 0 0 3 3 3 2 BTB/POZ domain TRP PF06011.12 RLN86342.1 - 4.2e-16 58.7 26.6 2.7e-15 56.0 23.9 2.2 1 1 1 2 2 2 2 Transient receptor potential (TRP) ion channel DUF2870 PF11069.8 RLN86343.1 - 3.2e-39 133.2 0.3 5e-39 132.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) TTL PF03133.15 RLN86344.1 - 1.3e-43 149.2 0.0 6.6e-40 137.1 0.0 2.2 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RLN86344.1 - 2.9e-06 26.7 0.1 9e-06 25.1 0.1 1.9 1 1 0 1 1 1 1 YheC/D like ATP-grasp Roughex PF06020.11 RLN86344.1 - 0.055 12.6 6.2 0.09 11.9 6.2 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Viral_helicase1 PF01443.18 RLN86346.1 - 5.3e-06 26.3 0.1 0.0021 17.8 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 RLN86346.1 - 0.00024 21.4 0.0 0.0005 20.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 RLN86346.1 - 0.0017 17.6 0.2 0.0029 16.8 0.2 1.3 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.6 RLN86346.1 - 0.0021 17.9 0.2 0.0051 16.6 0.2 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 RLN86346.1 - 0.0026 17.5 0.2 0.0052 16.5 0.2 1.4 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 RLN86346.1 - 0.011 13.7 0.1 0.041 11.8 0.1 1.8 2 0 0 2 2 2 0 Helicase AAA_29 PF13555.6 RLN86346.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN86346.1 - 0.026 14.9 0.2 0.094 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain MORN PF02493.20 RLN86349.1 - 7.5e-11 41.3 11.0 3e-07 29.9 2.8 3.5 3 0 0 3 3 3 2 MORN repeat Mu-transpos_C PF09299.11 RLN86349.1 - 0.056 13.4 0.0 0.26 11.3 0.0 2.1 1 0 0 1 1 1 0 Mu transposase, C-terminal UPF0029 PF01205.19 RLN86349.1 - 0.16 12.3 0.8 21 5.5 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein family UPF0029 3HCDH_RFF PF18321.1 RLN86350.1 - 0.03 14.7 2.6 0.078 13.4 0.4 2.9 3 0 0 3 3 3 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain DUF4200 PF13863.6 RLN86350.1 - 0.67 10.4 49.3 0.71 10.3 0.1 5.1 2 1 3 5 5 5 0 Domain of unknown function (DUF4200) Bacillus_HBL PF05791.11 RLN86350.1 - 7.9 6.3 16.8 0.031 14.1 4.6 2.9 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DHC_N1 PF08385.12 RLN86351.1 - 3e-185 617.1 7.5 3e-185 617.1 7.5 2.0 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 RLN86351.1 - 1.3e-135 451.6 0.0 1.4e-134 448.3 0.0 2.5 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN86351.1 - 1.2e-109 367.1 1.4 1.2e-109 367.1 1.4 2.8 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RLN86351.1 - 1.7e-81 273.4 0.0 1.6e-80 270.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 RLN86351.1 - 2.8e-76 256.7 0.0 1.7e-75 254.1 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 RLN86351.1 - 3.9e-66 222.3 0.0 4.5e-65 218.8 0.0 2.6 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 RLN86351.1 - 2e-46 157.8 0.0 2.4e-41 141.2 0.0 4.5 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RLN86351.1 - 7e-45 152.8 0.0 1.3e-44 151.9 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RLN86351.1 - 4.1e-38 130.1 0.0 6e-37 126.4 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 RLN86351.1 - 4.9e-33 114.6 8.2 1.2e-32 113.3 8.2 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 RLN86351.1 - 4.4e-18 65.6 0.1 1.3e-06 28.4 0.0 5.7 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 RLN86351.1 - 1.2e-17 64.2 0.0 5.4e-17 62.1 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RLN86351.1 - 1.3e-14 54.2 0.0 4.6e-14 52.4 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 RLN86351.1 - 8.1e-11 42.6 23.2 0.00015 22.2 0.4 7.3 6 1 0 6 6 5 4 AAA ATPase domain AAA PF00004.29 RLN86351.1 - 2.6e-10 40.8 0.8 0.23 11.9 0.0 4.8 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RLN86351.1 - 9e-07 28.7 0.7 0.00015 21.5 0.1 3.5 3 0 0 3 3 3 1 Sigma-54 interaction domain ABC_tran PF00005.27 RLN86351.1 - 4.6e-06 27.2 2.2 0.14 12.7 0.1 4.4 4 0 0 4 4 3 2 ABC transporter AAA_29 PF13555.6 RLN86351.1 - 8.7e-06 25.4 0.2 0.35 10.6 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN86351.1 - 4.1e-05 23.6 0.3 0.53 10.2 0.0 4.1 4 0 0 4 4 3 2 RsgA GTPase AAA_22 PF13401.6 RLN86351.1 - 6.1e-05 23.3 17.2 0.16 12.2 0.0 7.4 8 0 0 8 8 6 2 AAA domain Mg_chelatase PF01078.21 RLN86351.1 - 0.00013 21.5 0.9 1.5 8.2 0.0 4.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 RLN86351.1 - 0.00014 22.4 7.2 2.7 8.6 0.0 6.0 7 0 0 7 7 4 1 AAA domain DUF815 PF05673.13 RLN86351.1 - 0.00027 20.2 0.6 0.41 9.8 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 RLN86351.1 - 0.0005 20.3 1.4 25 5.0 0.1 4.9 4 0 0 4 4 4 0 AAA domain TsaE PF02367.17 RLN86351.1 - 0.0018 18.3 4.0 3.2 7.7 0.0 4.5 4 0 0 4 4 4 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 RLN86351.1 - 0.0034 17.7 0.1 20 5.6 0.0 3.8 3 0 0 3 3 3 0 RNA helicase AAA_30 PF13604.6 RLN86351.1 - 0.0084 15.9 18.0 0.12 12.1 0.0 5.1 6 0 0 6 6 5 2 AAA domain Roc PF08477.13 RLN86351.1 - 0.018 15.3 0.3 4.1 7.6 0.0 3.4 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 RLN86351.1 - 0.018 14.2 0.1 7.5 5.7 0.0 3.5 3 0 0 3 3 3 0 NB-ARC domain Sigma54_activ_2 PF14532.6 RLN86351.1 - 0.018 15.1 1.1 0.11 12.6 0.0 3.0 3 0 0 3 3 1 0 Sigma-54 interaction domain AAA_19 PF13245.6 RLN86351.1 - 0.02 15.2 0.8 52 4.2 0.0 4.2 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 RLN86351.1 - 0.029 14.5 0.2 16 5.6 0.1 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase Cytidylate_kin PF02224.18 RLN86351.1 - 0.1 12.3 0.9 5.2 6.7 0.1 3.6 4 0 0 4 4 3 0 Cytidylate kinase AAA_24 PF13479.6 RLN86351.1 - 0.21 11.3 2.8 25 4.5 0.0 4.2 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 RLN86351.1 - 0.3 11.0 10.2 0.99 9.3 0.0 4.4 5 0 0 5 5 3 0 NACHT domain Zeta_toxin PF06414.12 RLN86351.1 - 0.36 10.1 2.4 9 5.5 0.0 3.3 4 0 0 4 4 3 0 Zeta toxin AAA_23 PF13476.6 RLN86351.1 - 1.3 9.5 0.0 1.3 9.5 0.0 5.2 5 0 0 5 5 4 0 AAA domain PT PF04886.12 RLN86352.1 - 2.5e-09 36.5 50.3 1.3e+02 2.2 50.3 3.0 1 1 0 1 1 1 1 PT repeat Fer2 PF00111.27 RLN86353.1 - 2.7 8.0 15.6 8.6 6.4 1.1 3.6 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain DUF3320 PF11784.8 RLN86353.1 - 4.2 7.4 4.8 1.5e+02 2.5 0.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3320) PX PF00787.24 RLN86355.1 - 3e-07 30.4 1.1 4.5e-07 29.8 0.1 1.8 2 0 0 2 2 2 1 PX domain TFIIA PF03153.13 RLN86355.1 - 4.3 7.2 18.3 6.4 6.6 18.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Abhydrolase_1 PF00561.20 RLN86356.1 - 2.5e-18 66.7 0.1 4.3e-18 65.9 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN86356.1 - 1.3e-09 39.0 0.0 1.5e-09 38.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN86356.1 - 1.2e-05 24.7 0.0 1.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 RLN86356.1 - 0.00024 21.4 0.4 0.00061 20.1 0.4 1.7 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Ndr PF03096.14 RLN86356.1 - 0.004 15.9 0.0 0.0064 15.2 0.0 1.3 1 0 0 1 1 1 1 Ndr family NARP1 PF12569.8 RLN86357.1 - 7.8 5.3 11.2 38 3.0 10.2 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Cupin_4 PF08007.12 RLN86358.1 - 2.3e-60 204.7 0.0 3e-60 204.3 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 RLN86358.1 - 8.5e-07 28.9 0.0 8.4e-05 22.4 0.0 2.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_1 PF00190.22 RLN86358.1 - 0.037 13.7 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.11 RLN86358.1 - 0.1 12.4 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Cupin domain TIM PF00121.18 RLN86359.1 - 1.9e-80 269.7 0.1 7.7e-80 267.8 0.1 1.7 2 0 0 2 2 2 1 Triosephosphate isomerase TRP PF06011.12 RLN86360.1 - 1.3e-27 96.7 13.9 7.2e-27 94.2 13.9 1.9 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel FYVE PF01363.21 RLN86360.1 - 0.00049 20.2 9.3 0.00049 20.2 9.3 2.0 2 0 0 2 2 2 1 FYVE zinc finger Ninjurin PF04923.12 RLN86360.1 - 0.31 11.0 2.6 11 6.0 0.1 3.4 3 0 0 3 3 3 0 Ninjurin Ank_2 PF12796.7 RLN86361.1 - 3.3e-23 82.1 1.0 4e-10 40.2 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 RLN86361.1 - 2.2e-16 59.5 11.0 0.00021 21.6 0.2 6.5 5 1 1 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 RLN86361.1 - 2.5e-16 59.5 5.3 0.00023 21.4 0.0 5.7 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN86361.1 - 6.6e-16 58.5 1.5 8.9e-06 26.2 0.1 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN86361.1 - 1.6e-15 55.6 3.1 0.01 16.3 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat AAA_16 PF13191.6 RLN86361.1 - 9e-09 35.9 0.0 5.1e-07 30.2 0.0 3.2 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 RLN86361.1 - 4.1e-07 30.1 0.0 1.9e-06 27.9 0.0 2.2 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 RLN86361.1 - 8e-06 26.2 0.5 0.00053 20.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain Staufen_C PF16482.5 RLN86361.1 - 0.066 13.4 0.1 0.24 11.5 0.1 2.0 1 0 0 1 1 1 0 Staufen C-terminal domain DUF4449 PF14613.6 RLN86361.1 - 0.078 13.1 3.6 0.24 11.5 3.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) HTH_Tnp_1 PF01527.20 RLN86362.1 - 9.8e-05 22.6 0.0 0.00012 22.4 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 RLN86362.1 - 0.14 12.0 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain Pkinase_Tyr PF07714.17 RLN86363.1 - 3.8e-05 23.1 0.0 5.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ACT_4 PF13291.6 RLN86363.1 - 0.016 15.8 0.1 0.032 14.8 0.1 1.4 1 0 0 1 1 1 0 ACT domain HTH_29 PF13551.6 RLN86365.1 - 0.001 19.0 0.3 0.043 13.8 0.0 2.3 1 1 1 2 2 2 1 Winged helix-turn helix HTH_3 PF01381.22 RLN86365.1 - 0.0012 18.9 0.1 0.0027 17.7 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_24 PF13412.6 RLN86365.1 - 0.0016 18.0 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_26 PF13443.6 RLN86365.1 - 0.0029 18.0 0.1 0.016 15.6 0.1 2.1 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.6 RLN86365.1 - 0.006 16.3 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 RLN86365.1 - 0.026 14.7 0.4 0.47 10.6 0.1 2.4 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_10 PF04967.12 RLN86365.1 - 0.03 14.1 0.1 0.089 12.6 0.0 1.9 2 1 0 2 2 2 0 HTH DNA binding domain HTH_31 PF13560.6 RLN86365.1 - 0.033 14.5 1.7 0.1 13.0 1.7 2.1 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 RLN86365.1 - 0.045 13.8 0.0 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_Crp_2 PF13545.6 RLN86365.1 - 0.051 13.5 0.1 0.13 12.2 0.1 1.7 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 RLN86365.1 - 0.082 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_36 PF13730.6 RLN86365.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MerR PF00376.23 RLN86365.1 - 0.68 9.8 0.0 0.68 9.8 0.0 2.2 3 0 0 3 3 3 0 MerR family regulatory protein ZapB PF06005.12 RLN86367.1 - 0.032 14.7 2.3 0.032 14.7 2.3 4.4 1 1 4 5 5 5 0 Cell division protein ZapB NPV_P10 PF05531.12 RLN86367.1 - 0.14 12.6 7.2 3.8 8.0 0.9 3.7 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 RLN86367.1 - 0.16 12.0 11.0 1.3 9.1 0.9 3.8 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus TetR_C_24 PF17932.1 RLN86367.1 - 0.49 10.7 4.5 0.39 11.0 0.5 2.7 2 1 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Lectin_N PF03954.14 RLN86367.1 - 0.65 9.8 13.3 1.7 8.4 8.2 3.7 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF4618 PF15397.6 RLN86367.1 - 0.72 9.2 16.9 0.4 10.1 3.2 3.3 1 1 2 4 4 4 0 Domain of unknown function (DUF4618) V_ATPase_I PF01496.19 RLN86367.1 - 3.2 5.6 9.9 7.3 4.4 9.9 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Bacillus_HBL PF05791.11 RLN86367.1 - 7 6.4 11.5 2.2 8.1 1.3 3.1 2 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF5630 PF18632.1 RLN86368.1 - 0.031 13.6 0.5 0.5 9.6 0.2 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5630) ADK PF00406.22 RLN86369.1 - 4.4e-41 140.5 0.0 6.8e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 RLN86369.1 - 1.2e-18 67.9 0.0 4.1e-18 66.1 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 RLN86369.1 - 4.6e-07 30.1 0.2 0.0088 16.2 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.6 RLN86369.1 - 1.4e-06 28.9 0.0 8.1e-06 26.4 0.0 2.0 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 RLN86369.1 - 0.0019 18.2 0.0 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid Hydin_ADK PF17213.3 RLN86369.1 - 0.072 13.4 0.1 9.8 6.4 0.1 2.3 1 1 0 2 2 2 0 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 RLN86369.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase MCU PF04678.13 RLN86370.1 - 0.027 14.6 9.6 0.15 12.2 2.7 2.3 2 0 0 2 2 2 0 Mitochondrial calcium uniporter PWI PF01480.17 RLN86370.1 - 0.075 13.4 0.0 0.32 11.3 0.0 2.1 1 1 0 1 1 1 0 PWI domain Dynein_C PF18199.1 RLN86374.1 - 1.3e-111 372.8 0.0 1.4e-111 372.6 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain WD40 PF00400.32 RLN86375.1 - 5.7e-38 128.2 4.0 2.5e-08 34.4 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Tup_N PF08581.10 RLN86375.1 - 4.6e-22 78.1 6.5 7e-22 77.5 6.5 1.3 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 RLN86375.1 - 8.6e-14 51.6 0.0 7.9e-06 26.1 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN86375.1 - 4.9e-08 32.3 0.1 0.23 10.4 0.0 4.0 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 RLN86375.1 - 0.00013 21.4 0.7 0.37 10.1 0.0 3.5 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 RLN86375.1 - 0.0018 17.0 0.1 0.12 11.0 0.0 2.8 2 1 1 3 3 3 1 Nucleoporin Nup120/160 PD40 PF07676.12 RLN86375.1 - 0.0025 17.7 0.0 10 6.2 0.0 4.2 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 RLN86375.1 - 0.0046 16.9 0.0 0.094 12.6 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 RLN86375.1 - 0.01 15.2 0.0 4.9 6.4 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain Fez1 PF06818.15 RLN86375.1 - 0.011 16.2 0.6 0.02 15.3 0.6 1.4 1 0 0 1 1 1 0 Fez1 Golgin_A5 PF09787.9 RLN86375.1 - 0.019 14.5 2.4 0.031 13.7 2.4 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Cluap1 PF10234.9 RLN86375.1 - 0.052 12.9 4.1 0.078 12.4 4.1 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 TSNAXIP1_N PF15739.5 RLN86375.1 - 0.097 13.1 4.7 0.19 12.1 4.7 1.4 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus DUF3450 PF11932.8 RLN86375.1 - 0.4 9.9 6.6 0.96 8.7 6.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GAS PF13851.6 RLN86375.1 - 1.4 8.2 8.6 2.2 7.6 8.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FYVE PF01363.21 RLN86376.1 - 1.6e-16 60.2 12.4 3.3e-16 59.2 12.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 RLN86376.1 - 2.2e-10 41.3 0.9 7.5e-10 39.5 0.3 2.2 2 0 0 2 2 2 1 GAF domain FYVE_2 PF02318.16 RLN86376.1 - 0.0027 17.9 9.1 0.0043 17.3 7.6 2.0 2 0 0 2 2 2 1 FYVE-type zinc finger GAF_3 PF13492.6 RLN86376.1 - 0.011 16.0 0.0 0.049 14.0 0.0 2.2 1 1 0 1 1 1 0 GAF domain DUF1428 PF07237.11 RLN86376.1 - 0.13 12.5 0.0 0.43 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) LRR_4 PF12799.7 RLN86377.1 - 4e-37 125.6 55.4 1.5e-05 25.3 0.5 10.2 7 1 4 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN86377.1 - 1.1e-34 117.9 62.5 7.3e-09 35.3 4.0 9.6 5 3 7 12 12 12 10 Leucine rich repeat WW PF00397.26 RLN86377.1 - 3.9e-12 46.0 4.0 5e-05 23.3 0.1 3.5 3 0 0 3 3 3 3 WW domain TPR_1 PF00515.28 RLN86377.1 - 0.0018 18.0 0.2 2.5 8.1 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat LRR_6 PF13516.6 RLN86377.1 - 0.0029 17.5 49.0 1.6 9.0 0.1 12.7 13 0 0 13 13 13 2 Leucine Rich repeat LRR_1 PF00560.33 RLN86377.1 - 0.0081 16.6 46.3 6 7.8 0.1 13.8 14 1 0 14 14 14 1 Leucine Rich Repeat IQ PF00612.27 RLN86377.1 - 0.046 13.5 1.1 0.15 12.0 1.1 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif TPR_2 PF07719.17 RLN86377.1 - 0.12 12.5 11.3 0.16 12.2 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_hyd_101C PF17451.2 RLN86377.1 - 0.18 12.1 1.3 0.66 10.3 0.1 2.6 3 1 1 4 4 4 0 Glycosyl hydrolase 101 beta sandwich domain TPR_8 PF13181.6 RLN86377.1 - 0.37 11.1 2.3 4.1 7.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN86377.1 - 3.3 8.5 7.2 17 6.3 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribonuclease_T2 PF00445.18 RLN86379.1 - 9.2e-27 94.4 0.5 2.3e-26 93.1 0.5 1.6 1 1 0 1 1 1 1 Ribonuclease T2 family LOH1CR12 PF10158.9 RLN86379.1 - 0.21 11.6 0.1 0.33 11.0 0.1 1.2 1 0 0 1 1 1 0 Tumour suppressor protein HTH_Tnp_Tc5 PF03221.16 RLN86380.1 - 1.8e-09 37.5 0.0 3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_Tnp_1 PF01527.20 RLN86380.1 - 0.21 12.0 3.0 1.1 9.6 0.4 2.5 1 1 1 2 2 2 0 Transposase Methyltransf_23 PF13489.6 RLN86381.1 - 0.00011 22.1 0.0 0.00039 20.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain zf-MYND PF01753.18 RLN86381.1 - 0.0012 18.9 10.9 0.0012 18.9 10.9 2.0 2 0 0 2 2 2 1 MYND finger Methyltransf_25 PF13649.6 RLN86381.1 - 0.034 14.9 0.0 0.11 13.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain DUF3827 PF12877.7 RLN86381.1 - 0.056 11.8 2.9 0.23 9.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) CytochromB561_N PF09786.9 RLN86381.1 - 0.076 12.0 0.1 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal Methyltransf_32 PF13679.6 RLN86381.1 - 0.14 12.1 0.0 0.14 12.1 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain Ecl1 PF12855.7 RLN86381.1 - 0.14 13.3 0.3 0.14 13.3 0.3 3.1 3 0 0 3 3 3 0 ECL1/2/3 zinc binding proteins Cyclotide PF03784.13 RLN86381.1 - 0.15 12.2 3.1 0.47 10.6 3.1 1.9 1 0 0 1 1 1 0 Cyclotide family cNMP_binding PF00027.29 RLN86382.1 - 3.5e-21 75.1 0.0 1.2e-11 44.6 0.1 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain ubiquitin PF00240.23 RLN86382.1 - 3.4e-10 39.5 0.0 1e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 RLN86382.1 - 4.2e-05 23.3 0.0 8.6e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 RLN86382.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain MBT PF02820.18 RLN86383.1 - 5e-15 55.6 9.1 0.0067 16.7 0.2 6.2 6 0 0 6 6 6 5 mbt repeat Tudor-knot PF11717.8 RLN86383.1 - 7.7e-10 38.5 15.3 0.0097 15.8 0.7 5.6 5 0 0 5 5 5 3 RNA binding activity-knot of a chromodomain Tudor_4 PF18358.1 RLN86383.1 - 3.9e-09 36.0 10.4 0.0046 16.5 0.4 4.3 3 0 0 3 3 3 3 Histone methyltransferase Tudor domain SAWADEE PF16719.5 RLN86383.1 - 5.3e-05 23.3 5.0 0.24 11.4 0.6 3.6 3 0 0 3 3 3 2 SAWADEE domain DUSP PF06337.12 RLN86383.1 - 7.1e-05 23.4 0.0 0.00018 22.0 0.0 1.8 1 0 0 1 1 1 1 DUSP domain DUSP PF06337.12 RLN86384.1 - 2e-06 28.3 0.2 8.5e-06 26.3 0.2 1.9 1 1 0 1 1 1 1 DUSP domain UCH PF00443.29 RLN86385.1 - 1.2e-74 251.1 0.0 1.6e-74 250.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN86385.1 - 1.9e-11 44.1 0.0 5.2e-05 23.0 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase MBT PF02820.18 RLN86385.1 - 0.0017 18.7 0.2 0.29 11.5 0.1 2.6 2 0 0 2 2 2 1 mbt repeat Tudor_4 PF18358.1 RLN86385.1 - 0.0027 17.3 1.0 0.0064 16.1 1.0 1.7 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain CUE PF02845.16 RLN86385.1 - 0.0075 15.9 0.1 0.016 14.9 0.1 1.5 1 0 0 1 1 1 1 CUE domain Tudor-knot PF11717.8 RLN86385.1 - 0.018 14.9 4.4 0.33 10.9 2.4 2.8 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain USP7_C2 PF14533.6 RLN86385.1 - 0.038 13.7 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal Phage_integrase PF00589.22 RLN86389.1 - 0.0031 17.3 0.0 0.011 15.5 0.0 2.0 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_5 PF13102.6 RLN86389.1 - 0.051 13.9 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 Phage integrase SAM-like domain ADIP PF11559.8 RLN86389.1 - 0.066 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4904 PF16247.5 RLN86389.1 - 0.19 11.5 0.1 0.56 10.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4904) Retrotran_gag_2 PF14223.6 RLN86390.1 - 6.9e-11 42.0 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type GLE1 PF07817.13 RLN86390.1 - 0.0012 18.1 0.1 0.0017 17.6 0.1 1.2 1 0 0 1 1 1 1 GLE1-like protein ELO PF01151.18 RLN86391.1 - 0.00019 21.0 0.3 0.00024 20.7 0.3 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family SBP_bac_11 PF13531.6 RLN86392.1 - 1e-35 123.6 0.1 1.6e-35 122.9 0.1 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 RLN86392.1 - 4.2e-07 30.2 0.3 5.6e-06 26.5 0.3 2.2 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 RLN86392.1 - 0.0011 18.5 0.0 0.0024 17.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 RLN86392.1 - 0.014 15.3 0.2 0.039 13.8 0.0 1.9 2 1 0 2 2 2 0 Bacterial extracellular solute-binding protein ODV-E18 PF10717.9 RLN86392.1 - 0.031 14.1 1.0 0.072 13.0 1.0 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF5061 PF16587.5 RLN86392.1 - 0.14 12.2 0.1 0.35 10.9 0.1 1.6 1 0 0 1 1 1 0 17 kDa common-antigen outer membrane protein OapA_N PF08525.11 RLN86392.1 - 2.8 8.0 4.5 4.8 7.2 4.5 1.4 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif PrmA PF06325.13 RLN86393.1 - 1.2e-10 41.3 0.0 1.8e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 RLN86393.1 - 1.9e-09 38.1 0.0 8.4e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN86393.1 - 3.3e-06 27.6 0.0 1.1e-05 26.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 RLN86393.1 - 1.4e-05 24.7 0.0 0.0001 21.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 RLN86393.1 - 6.4e-05 22.8 0.0 0.00013 21.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 RLN86393.1 - 0.00068 19.6 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN86393.1 - 0.0011 18.8 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PRMT5_C PF17286.2 RLN86393.1 - 0.0017 18.2 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5 PF05185.16 RLN86393.1 - 0.0022 17.9 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CMAS PF02353.20 RLN86393.1 - 0.0025 17.1 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 RLN86393.1 - 0.033 13.1 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_24 PF13578.6 RLN86393.1 - 0.085 13.9 0.0 0.17 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 RLN86393.1 - 0.098 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Cons_hypoth95 PF03602.15 RLN86393.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PALP PF00291.25 RLN86393.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Peptidase_S41 PF03572.18 RLN86394.1 - 2.4e-08 33.7 0.0 0.00011 21.8 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S41 Tricorn_C1 PF14684.6 RLN86394.1 - 0.16 12.0 0.1 0.32 11.1 0.1 1.4 1 0 0 1 1 1 0 Tricorn protease C1 domain SOCS PF12610.8 RLN86395.1 - 0.076 13.4 1.7 0.21 12.0 1.7 1.7 1 0 0 1 1 1 0 Suppressor of cytokine signalling Ricin_B_lectin PF00652.22 RLN86396.1 - 2.4e-40 137.7 29.6 8.4e-16 58.4 4.6 3.6 2 1 0 3 3 3 3 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 RLN86396.1 - 1.3e-12 47.5 6.7 3.8e-05 23.3 0.2 4.3 3 1 1 4 4 4 4 Cytolethal distending toxin A/C domain DUF346 PF03984.13 RLN86396.1 - 0.11 12.3 3.9 0.11 12.3 0.3 3.0 2 0 0 2 2 2 0 Repeat of unknown function (DUF346) PUL PF08324.11 RLN86398.1 - 1.7e-36 125.9 2.2 2.8e-36 125.2 2.2 1.3 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 RLN86398.1 - 8e-30 102.5 11.2 8.2e-08 32.8 0.2 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat PFU PF09070.11 RLN86398.1 - 9.6e-23 80.6 0.0 1.6e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) ANAPC4_WD40 PF12894.7 RLN86398.1 - 0.00026 21.2 0.0 0.0011 19.2 0.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 RLN86398.1 - 0.038 14.5 0.8 2.7 8.6 0.1 3.8 3 0 0 3 3 3 0 PQQ-like domain WD40 PF00400.32 RLN86399.1 - 1.9e-05 25.4 6.4 2 9.4 0.0 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat FlaC_arch PF05377.11 RLN86399.1 - 0.018 15.4 2.4 0.041 14.3 2.4 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) PD40 PF07676.12 RLN86399.1 - 0.025 14.5 0.0 0.13 12.3 0.0 2.2 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat NleF_casp_inhib PF16809.5 RLN86399.1 - 0.036 14.0 1.2 0.07 13.0 0.2 1.8 2 0 0 2 2 2 0 NleF caspase inhibitor ANAPC4_WD40 PF12894.7 RLN86399.1 - 0.086 13.1 0.0 10 6.5 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Spc7 PF08317.11 RLN86399.1 - 0.7 8.7 8.7 1.1 8.0 8.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 RLN86399.1 - 0.74 10.3 13.1 1.6 9.3 13.1 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region UPF0242 PF06785.11 RLN86399.1 - 1 9.5 4.9 1.9 8.6 4.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TFIIA PF03153.13 RLN86399.1 - 1.1 9.1 17.7 1.7 8.5 17.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAP1 PF07218.11 RLN86399.1 - 2.7 6.2 7.3 4.1 5.6 7.3 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DivIC PF04977.15 RLN86399.1 - 3.2 7.6 8.2 0.35 10.7 3.5 1.9 2 0 0 2 2 2 0 Septum formation initiator MPS2 PF17060.5 RLN86399.1 - 5.2 6.2 8.9 6 6.0 7.8 1.6 2 0 0 2 2 2 0 Monopolar spindle protein 2 ABC_membrane PF00664.23 RLN86400.1 - 5.9e-28 98.3 8.1 5.9e-28 98.3 8.1 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN86400.1 - 2.6e-27 96.0 0.0 4.9e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN86400.1 - 1.6e-07 31.0 0.2 1.3e-05 24.8 0.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RLN86400.1 - 3e-05 24.5 0.1 0.00013 22.4 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RLN86400.1 - 0.00037 20.8 0.2 0.0051 17.1 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 RLN86400.1 - 0.00056 19.8 0.1 0.052 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN86400.1 - 0.00076 19.4 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN86400.1 - 0.0087 15.8 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 RLN86400.1 - 0.011 16.2 0.0 0.16 12.4 0.0 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 RLN86400.1 - 0.024 14.4 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 RLN86400.1 - 0.04 14.4 0.0 0.085 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 RLN86400.1 - 0.061 13.2 0.1 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.6 RLN86400.1 - 0.065 13.5 0.5 0.4 10.9 0.1 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 RLN86400.1 - 0.067 12.8 0.0 0.43 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 RLN86400.1 - 0.088 13.0 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 RLN86400.1 - 0.14 11.0 0.1 2.2 7.0 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 RLN86400.1 - 0.14 11.9 0.0 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF4129 PF13559.6 RLN86400.1 - 0.15 12.3 0.0 13 6.2 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) AAA_15 PF13175.6 RLN86400.1 - 0.2 11.4 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain PH PF00169.29 RLN86401.1 - 5.5e-08 33.3 0.0 1.3e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN86401.1 - 0.00017 22.0 0.8 0.013 15.9 0.1 3.4 2 1 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 RLN86401.1 - 0.0002 21.6 0.0 0.00082 19.6 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain WW PF00397.26 RLN86401.1 - 0.0014 18.7 0.8 0.0027 17.8 0.8 1.5 1 0 0 1 1 1 1 WW domain ABC_tran_CTD PF16326.5 RLN86401.1 - 0.0045 17.2 2.0 0.0045 17.2 2.0 4.7 3 1 0 4 4 4 1 ABC transporter C-terminal domain PH_8 PF15409.6 RLN86401.1 - 0.0077 16.5 0.0 0.019 15.3 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PspA_IM30 PF04012.12 RLN86401.1 - 0.074 12.6 29.4 0.058 13.0 9.7 2.6 2 0 0 2 2 2 0 PspA/IM30 family Taxilin PF09728.9 RLN86401.1 - 0.095 11.9 31.5 0.076 12.2 0.6 4.2 3 1 1 4 4 4 0 Myosin-like coiled-coil protein Seryl_tRNA_N PF02403.22 RLN86401.1 - 0.2 11.9 33.8 2 8.7 3.0 4.3 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain YabA PF06156.13 RLN86401.1 - 0.58 10.8 22.6 3.2 8.5 0.8 4.3 3 1 1 4 4 4 0 Initiation control protein YabA GAS PF13851.6 RLN86401.1 - 3.2 7.1 35.1 0.24 10.7 1.1 4.3 5 0 0 5 5 5 0 Growth-arrest specific micro-tubule binding SlyX PF04102.12 RLN86401.1 - 3.8 8.2 21.9 2.3 8.9 0.5 4.6 4 1 0 4 4 4 0 SlyX FlxA PF14282.6 RLN86401.1 - 8.5 6.4 25.6 0.027 14.4 1.5 3.8 2 1 1 3 3 3 0 FlxA-like protein CRT10 PF08728.10 RLN86401.1 - 9.9 4.2 9.5 1.9 6.5 4.6 1.9 2 0 0 2 2 2 0 CRT10 Retrotran_gag_2 PF14223.6 RLN86402.1 - 1.1e-07 31.5 0.0 2.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Med3 PF11593.8 RLN86402.1 - 1.4 8.0 15.5 1.7 7.7 8.6 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal LRR_8 PF13855.6 RLN86403.1 - 1.8e-28 98.0 23.5 3.2e-07 30.0 1.5 7.1 4 2 4 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 RLN86403.1 - 9e-25 86.3 17.4 9.5e-05 22.7 0.7 8.6 5 2 4 10 10 10 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN86403.1 - 1.3e-07 31.3 6.0 0.13 11.7 0.1 3.4 2 1 1 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 RLN86403.1 - 2.1e-05 24.2 15.7 2.6 8.3 0.1 7.8 7 0 0 7 7 7 2 Leucine Rich repeat ubiquitin PF00240.23 RLN86403.1 - 9.1e-05 22.1 1.1 0.00034 20.3 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin family LRR_1 PF00560.33 RLN86403.1 - 0.032 14.8 24.1 27 5.9 0.5 9.5 10 3 0 10 10 10 0 Leucine Rich Repeat Ubiquitin_2 PF14560.6 RLN86403.1 - 0.056 13.9 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain Nucleo_P87 PF07267.11 RLN86403.1 - 7 5.4 7.4 11 4.8 7.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FYVE PF01363.21 RLN86404.1 - 6.7e-11 42.2 11.3 1.9e-10 40.7 11.3 1.8 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 RLN86404.1 - 6.5e-06 26.8 0.2 2.1e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 GAF domain FYVE_2 PF02318.16 RLN86404.1 - 0.0087 16.3 5.1 0.025 14.8 5.1 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger RCC1 PF00415.18 RLN86405.1 - 2e-46 156.4 8.6 9.3e-10 39.0 0.0 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN86405.1 - 2.7e-21 74.8 25.8 9.1e-09 34.9 0.4 6.4 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat PA PF02225.22 RLN86405.1 - 3.3e-05 23.8 0.2 0.47 10.5 0.0 2.8 2 0 0 2 2 2 2 PA domain Ribosomal_S27e PF01667.17 RLN86407.1 - 2.2e-28 97.7 4.3 2.6e-28 97.5 4.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-CSL PF05207.13 RLN86407.1 - 0.032 14.0 1.9 0.057 13.2 1.9 1.5 1 1 0 1 1 1 0 CSL zinc finger GLE1 PF07817.13 RLN86408.1 - 7.4e-32 110.5 0.0 7.4e-32 110.5 0.0 2.4 4 0 0 4 4 4 1 GLE1-like protein GRP PF07172.11 RLN86408.1 - 0.016 15.9 16.3 0.016 15.9 16.3 2.9 2 1 0 2 2 2 0 Glycine rich protein family Aldedh PF00171.22 RLN86409.1 - 5.9e-108 361.3 1.9 3.9e-70 236.6 0.7 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Gly-zipper_YMGG PF13441.6 RLN86409.1 - 0.068 12.9 4.5 0.19 11.5 4.5 1.8 1 0 0 1 1 1 0 YMGG-like Gly-zipper HA PF03457.14 RLN86410.1 - 4.8e-33 113.3 9.5 0.00011 22.4 0.0 7.7 7 1 0 7 7 7 7 Helicase associated domain PG_binding_2 PF08823.11 RLN86410.1 - 0.038 14.3 0.7 3.7 7.9 0.0 3.8 4 0 0 4 4 4 0 Putative peptidoglycan binding domain Phosphoesterase PF04185.14 RLN86410.1 - 0.073 12.2 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoesterase family LSM PF01423.22 RLN86411.1 - 6.4e-16 57.8 0.3 7.2e-16 57.6 0.3 1.0 1 0 0 1 1 1 1 LSM domain N2227 PF07942.12 RLN86412.1 - 1.4e-75 254.0 0.1 4.7e-71 239.2 0.0 2.8 1 1 1 2 2 2 2 N2227-like protein NNMT_PNMT_TEMT PF01234.17 RLN86412.1 - 0.0019 17.4 0.0 0.003 16.8 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.6 RLN86412.1 - 0.0052 16.6 0.0 0.014 15.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN86412.1 - 0.0071 17.1 0.0 0.055 14.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN86412.1 - 0.0092 16.6 0.0 0.21 12.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN86412.1 - 0.19 12.4 0.0 7 7.4 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain TPR_12 PF13424.6 RLN86414.1 - 0.07 13.4 0.6 0.83 10.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN86414.1 - 0.15 12.3 0.2 70 3.9 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_L37 PF08561.10 RLN86415.1 - 3.3e-09 37.3 1.1 6.5e-08 33.1 0.0 2.0 1 1 1 2 2 2 1 Mitochondrial ribosomal protein L37 EF_assoc_1 PF08355.12 RLN86415.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 EF hand associated Ras PF00071.22 RLN86416.1 - 0.067 12.8 0.2 0.97 9.0 0.0 2.2 2 0 0 2 2 2 0 Ras family CbiA PF01656.23 RLN86416.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 RLN86416.1 - 0.13 11.8 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 RLN86416.1 - 0.21 10.5 0.0 0.37 9.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain GTP_EFTU PF00009.27 RLN86417.1 - 9.8e-39 132.9 0.1 8.5e-38 129.8 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 RLN86417.1 - 7.9e-10 38.6 0.0 1.7e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 RLN86417.1 - 5.9e-07 29.8 0.2 1.1e-06 28.9 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RLN86417.1 - 0.0027 17.8 0.0 0.0055 16.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 RLN86417.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain gag_pre-integrs PF13976.6 RLN86419.1 - 0.0014 18.5 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 RLN86419.1 - 0.15 11.8 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF2508 PF10704.9 RLN86423.1 - 0.044 14.0 2.0 2.6 8.3 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Tau95 PF09734.9 RLN86427.1 - 0.014 16.2 0.7 0.029 15.2 0.7 1.5 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain EMP24_GP25L PF01105.24 RLN86427.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD TSC22 PF01166.18 RLN86427.1 - 0.13 12.6 3.0 0.83 10.0 2.7 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family SPX PF03105.19 RLN86428.1 - 0.033 14.1 10.4 0.047 13.6 10.4 1.1 1 0 0 1 1 1 0 SPX domain UPF0242 PF06785.11 RLN86428.1 - 0.24 11.5 5.0 0.39 10.8 5.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus adh_short PF00106.25 RLN86431.1 - 2.9e-25 88.9 0.1 1.2e-24 86.9 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN86431.1 - 3.3e-15 56.3 0.0 4.5e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN86431.1 - 3.3e-06 27.1 0.0 5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN86431.1 - 0.035 13.6 0.1 0.068 12.6 0.1 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 RLN86431.1 - 0.12 11.7 0.1 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RLN86432.1 - 1.4e-16 60.8 7.5 8.5e-13 48.3 2.2 2.8 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 RLN86432.1 - 1.7e-06 27.3 0.0 5.6e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 RLN86432.1 - 3.4e-06 26.9 0.4 8.3e-06 25.6 0.4 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RLN86432.1 - 1.4e-05 25.3 2.3 4.1e-05 23.7 2.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 RLN86432.1 - 1.5e-05 24.4 0.2 2.8e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 RLN86432.1 - 2.3e-05 23.5 5.6 0.0059 15.5 1.2 2.3 2 0 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.14 RLN86432.1 - 0.0022 16.7 1.5 0.0087 14.8 1.0 1.9 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 RLN86432.1 - 0.009 15.1 1.9 0.014 14.5 1.9 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 RLN86432.1 - 0.031 14.8 1.9 0.083 13.5 0.9 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 RLN86432.1 - 0.049 12.9 0.5 0.085 12.1 0.5 1.3 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 RLN86432.1 - 0.052 13.4 0.4 0.095 12.6 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 RLN86432.1 - 0.052 12.9 0.4 0.081 12.3 0.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 RLN86432.1 - 0.068 12.2 0.3 0.068 12.2 0.3 1.9 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 RLN86432.1 - 0.072 12.2 4.8 0.13 11.4 4.8 1.4 1 0 0 1 1 1 0 FAD binding domain AAA_9 PF12781.7 RLN86433.1 - 1.6e-87 292.2 0.1 1.9e-86 288.8 0.4 2.3 2 0 0 2 2 2 1 ATP-binding dynein motor region Dynein_heavy PF03028.15 RLN86433.1 - 2.6e-43 146.9 0.0 2.6e-41 140.4 0.0 3.0 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 RLN86433.1 - 4.2e-29 101.5 0.2 1.1e-28 100.1 0.2 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 RLN86433.1 - 1.2e-23 83.7 0.4 2.3e-23 82.8 0.4 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor UPF0242 PF06785.11 RLN86433.1 - 0.0043 17.2 1.9 0.011 15.9 1.9 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus ADAM_spacer1 PF05986.14 RLN86433.1 - 0.22 11.6 1.1 0.85 9.7 0.0 2.4 2 1 1 3 3 3 0 ADAM-TS Spacer 1 PAP_central PF04928.17 RLN86435.1 - 0.036 13.1 0.0 0.036 13.1 0.0 1.0 1 0 0 1 1 1 0 Poly(A) polymerase central domain PTRF_SDPR PF15237.6 RLN86436.1 - 0.028 14.0 0.5 0.031 13.9 0.5 1.1 1 0 0 1 1 1 0 PTRF/SDPR family Pkinase_Tyr PF07714.17 RLN86437.1 - 1.1e-50 172.3 0.0 2.6e-40 138.4 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 RLN86437.1 - 3.2e-45 154.6 0.0 2.3e-35 122.2 0.0 3.3 3 0 0 3 3 3 2 Protein kinase domain TFIID_30kDa PF03540.13 RLN86437.1 - 2.2e-20 72.3 0.1 5.6e-20 71.0 0.1 1.8 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Arm PF00514.23 RLN86437.1 - 4.9e-13 48.6 5.7 0.0081 16.2 0.0 8.2 9 0 0 9 9 9 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN86437.1 - 0.00096 19.5 7.4 0.0051 17.2 1.6 5.6 4 2 2 6 6 6 4 HEAT repeats Kinase-like PF14531.6 RLN86437.1 - 0.01 15.2 0.0 1 8.6 0.0 2.6 2 0 0 2 2 2 0 Kinase-like HEAT_EZ PF13513.6 RLN86437.1 - 0.21 12.1 9.7 1.2 9.7 0.1 4.2 4 0 0 4 4 4 0 HEAT-like repeat DUF2795 PF11387.8 RLN86438.1 - 0.054 13.7 2.4 0.21 11.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2795) MatE PF01554.18 RLN86439.1 - 5.5e-45 152.9 30.7 3.8e-30 104.7 11.0 3.2 2 1 1 3 3 3 3 MatE SH3_3 PF08239.11 RLN86441.1 - 4e-10 39.8 0.8 0.0041 17.4 0.0 3.3 3 0 0 3 3 3 3 Bacterial SH3 domain RBD PF02196.15 RLN86442.1 - 0.008 16.2 0.1 0.79 9.8 0.1 2.5 2 0 0 2 2 2 2 Raf-like Ras-binding domain GST_N_3 PF13417.6 RLN86443.1 - 2.6e-16 59.8 0.0 4.3e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RLN86443.1 - 1.3e-14 54.3 0.0 2.5e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN86443.1 - 9.9e-12 45.0 0.0 2.1e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RLN86443.1 - 4.3e-05 23.6 0.0 7.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RLN86443.1 - 0.00013 21.9 0.4 0.0074 16.3 0.2 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RLN86443.1 - 0.00031 20.9 0.0 0.00051 20.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 RLN86443.1 - 0.0017 18.5 0.0 0.0054 16.9 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin GST_C_5 PF16865.5 RLN86443.1 - 0.15 12.6 0.0 0.24 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Rtf2 PF04641.12 RLN86444.1 - 6.8e-63 212.5 15.4 2.4e-61 207.4 15.4 2.0 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 RLN86444.1 - 0.00049 19.8 0.4 0.84 9.5 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit DUF1411 PF07199.11 RLN86444.1 - 0.039 13.6 0.3 0.076 12.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) zf-NOSIP PF15906.5 RLN86444.1 - 0.069 13.3 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 RLN86444.1 - 0.22 11.6 2.5 2.3 8.3 0.4 2.6 2 1 0 2 2 2 0 RING-type zinc-finger Neur_chan_memb PF02932.16 RLN86444.1 - 0.29 11.2 2.7 0.38 10.8 2.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Raftlin PF15250.6 RLN86444.1 - 0.36 9.5 9.2 0.49 9.1 9.2 1.1 1 0 0 1 1 1 0 Raftlin Hid1 PF12722.7 RLN86444.1 - 0.81 7.7 3.5 0.91 7.6 3.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 RLN86444.1 - 1.5 8.0 5.0 1.9 7.7 5.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Pol_alpha_B_N PF08418.10 RLN86444.1 - 2.1 8.3 12.0 3.6 7.5 12.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Arginosuc_synth PF00764.19 RLN86445.1 - 1e-153 512.3 0.0 1.5e-153 511.7 0.0 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase ADH_N PF08240.12 RLN86445.1 - 7.9e-26 90.1 1.1 2.4e-25 88.5 1.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN86445.1 - 1.4e-21 76.8 1.8 6.1e-21 74.8 0.2 2.7 2 1 1 3 3 3 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN86445.1 - 0.0036 16.7 0.1 0.0073 15.7 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 RLN86445.1 - 0.012 16.6 0.0 0.049 14.7 0.0 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase QueC PF06508.13 RLN86445.1 - 0.029 13.9 0.0 0.029 13.9 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC AlaDh_PNT_C PF01262.21 RLN86445.1 - 0.043 13.1 0.6 0.087 12.1 0.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 RLN86445.1 - 0.069 12.7 0.4 0.13 11.9 0.4 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FmiP_Thoc5 PF09766.9 RLN86447.1 - 0.43 9.8 1.1 0.7 9.1 1.1 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 Pro_isomerase PF00160.21 RLN86448.1 - 1.6e-33 116.2 0.0 3.5e-18 66.4 0.0 2.4 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FTP PF07504.13 RLN86448.1 - 0.033 14.0 0.2 0.068 13.0 0.2 1.4 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif ILVD_EDD PF00920.21 RLN86449.1 - 1.3e-23 83.4 0.0 1.6e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family Arm PF00514.23 RLN86455.1 - 3.4e-05 23.7 31.1 2 8.5 0.0 10.9 11 0 0 11 11 11 5 Armadillo/beta-catenin-like repeat ParcG PF10274.9 RLN86455.1 - 0.2 11.8 0.4 0.65 10.1 0.4 1.9 1 0 0 1 1 1 0 Parkin co-regulated protein HEAT_EZ PF13513.6 RLN86455.1 - 0.32 11.5 12.7 0.68 10.5 0.2 6.7 6 1 1 7 7 7 0 HEAT-like repeat Utp12 PF04003.12 RLN86455.1 - 0.67 10.3 6.9 2.2 8.6 2.8 3.1 2 0 0 2 2 2 0 Dip2/Utp12 Family TENA_THI-4 PF03070.16 RLN86456.1 - 0.014 15.2 0.1 0.023 14.5 0.1 1.3 1 1 0 1 1 1 0 TENA/THI-4/PQQC family Cauli_VI PF01693.16 RLN86459.1 - 1.1e-31 108.9 6.3 5.9e-16 58.5 0.9 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 RLN86459.1 - 9e-06 25.9 0.0 1.5e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 RNase H Pirin PF02678.16 RLN86460.1 - 1.8e-26 92.2 0.0 4.1e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 RLN86460.1 - 2.8e-26 91.9 0.0 9.5e-26 90.2 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin_C_2 PF17954.1 RLN86460.1 - 0.0026 17.9 0.0 0.016 15.4 0.0 2.2 2 0 0 2 2 2 1 Quercetinase C-terminal cupin domain Acid_PPase PF12689.7 RLN86461.1 - 6e-51 172.6 0.0 7.7e-51 172.3 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase F-box-like PF12937.7 RLN86462.1 - 0.027 14.4 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 F-box-like SMC_hinge PF06470.13 RLN86462.1 - 0.097 13.0 0.0 0.32 11.3 0.0 2.0 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain TSNAXIP1_N PF15739.5 RLN86462.1 - 0.15 12.4 0.0 0.84 10.0 0.0 2.1 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus Rubis-subs-bind PF09273.11 RLN86463.1 - 5.3e-12 46.5 0.2 1.1e-11 45.5 0.2 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding FYVE_2 PF02318.16 RLN86464.1 - 0.18 12.1 5.9 0.67 10.2 5.9 2.0 1 0 0 1 1 1 0 FYVE-type zinc finger IBR PF01485.21 RLN86464.1 - 3.4 8.0 9.1 0.88 9.8 3.5 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain HOOK PF05622.12 RLN86465.1 - 1.7e-08 33.2 21.3 1.7e-08 33.2 21.3 7.0 1 1 4 5 5 5 2 HOOK protein DDE_Tnp_2 PF04693.12 RLN86465.1 - 0.039 13.2 1.2 0.3 10.3 0.3 2.3 2 0 0 2 2 2 0 Archaeal putative transposase ISC1217 SAM_1 PF00536.30 RLN86465.1 - 0.097 13.1 1.1 0.26 11.8 0.1 2.2 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) RHH_8 PF17723.1 RLN86465.1 - 0.26 11.5 14.1 1.5 9.1 2.3 4.6 3 1 1 4 4 4 0 Ribbon-Helix-Helix transcriptional regulator family HALZ PF02183.18 RLN86465.1 - 0.26 11.5 0.0 0.26 11.5 0.0 7.5 7 0 0 7 7 7 0 Homeobox associated leucine zipper TSC22 PF01166.18 RLN86465.1 - 6.8 7.1 21.5 0.97 9.8 0.4 7.5 5 2 3 8 8 8 0 TSC-22/dip/bun family Alpha_kinase PF02816.18 RLN86467.1 - 5.5e-52 176.6 0.2 1.1e-51 175.6 0.0 1.6 2 0 0 2 2 2 1 Alpha-kinase family SR-25 PF10500.9 RLN86467.1 - 3.1 7.3 17.8 0.3 10.7 2.4 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF5427 PF10310.9 RLN86467.1 - 6.4 5.6 12.2 1.9 7.4 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5427) CLASP_N PF12348.8 RLN86468.1 - 2.8e-15 56.5 4.4 2.3e-08 33.9 0.1 4.3 4 0 0 4 4 4 2 CLASP N terminal HEAT PF02985.22 RLN86468.1 - 3.9e-08 32.9 0.6 11 6.5 0.0 9.1 9 0 0 9 9 9 1 HEAT repeat Cnd1 PF12717.7 RLN86468.1 - 7.7e-05 22.8 0.9 0.016 15.3 0.0 4.4 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 TAN PF11640.8 RLN86468.1 - 0.039 14.1 0.0 12 6.0 0.0 3.0 2 1 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Pirin PF02678.16 RLN86469.1 - 1.9e-20 72.8 0.0 3e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Pirin tRNA_anti-codon PF01336.25 RLN86471.1 - 0.00039 20.3 0.0 0.0012 18.7 0.0 1.9 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 RLN86471.1 - 0.0027 17.9 0.1 0.046 13.9 0.0 2.3 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF4246 PF14033.6 RLN86472.1 - 3.2e-49 168.3 0.0 3.9e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 RLN86472.1 - 0.00052 20.4 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 RLN86472.1 - 0.054 14.4 0.1 0.074 13.9 0.1 1.4 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Acid_PPase PF12689.7 RLN86473.1 - 1.5e-49 168.1 0.0 1.7e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Acid_PPase PF12689.7 RLN86474.1 - 6.9e-45 152.9 0.0 8.2e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase Pkinase PF00069.25 RLN86477.1 - 2.7e-49 167.9 0.0 3.8e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN86477.1 - 7.4e-49 166.4 0.0 1.1e-48 165.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Halogen_Hydrol PF10112.9 RLN86477.1 - 0.055 13.5 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Kinase-like PF14531.6 RLN86477.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF953 PF06110.11 RLN86478.1 - 2e-29 101.6 0.0 1e-20 73.5 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF953) Thioredoxin_2 PF13098.6 RLN86478.1 - 0.087 13.3 0.2 7 7.1 0.0 3.2 2 2 0 2 2 2 0 Thioredoxin-like domain Brix PF04427.18 RLN86479.1 - 1.8e-29 103.2 0.0 1.2e-27 97.3 0.0 2.1 1 1 0 1 1 1 1 Brix domain ArfGap PF01412.18 RLN86480.1 - 1.5e-33 115.4 0.0 3.7e-33 114.1 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 RLN86480.1 - 4.1e-22 79.1 0.4 1.5e-11 44.5 0.0 2.4 2 0 0 2 2 2 2 BAR domain of APPL family PH PF00169.29 RLN86480.1 - 3e-07 30.9 0.0 6.6e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 RLN86480.1 - 3.8e-07 30.5 0.1 1.1e-06 29.1 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN86480.1 - 6.1e-07 29.6 0.5 1.7e-06 28.2 0.5 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN86480.1 - 0.00024 21.6 0.1 0.00071 20.1 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Phage_TAC_11 PF11836.8 RLN86480.1 - 0.037 14.2 2.1 0.11 12.6 0.3 2.7 2 0 0 2 2 2 0 Phage tail tube protein, GTA-gp10 Ank PF00023.30 RLN86480.1 - 0.056 13.9 0.2 0.38 11.3 0.2 2.6 1 0 0 1 1 1 0 Ankyrin repeat Ion_trans PF00520.31 RLN86481.1 - 9.2e-80 267.4 45.6 1.5e-43 148.8 13.9 2.3 2 0 0 2 2 2 2 Ion transport protein EF-hand_1 PF00036.32 RLN86481.1 - 8.4e-12 43.8 3.1 5.1e-06 25.6 0.9 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 RLN86481.1 - 3.7e-09 36.9 0.1 8.4e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair PKD_channel PF08016.12 RLN86481.1 - 7.5e-09 34.8 32.9 4e-06 25.8 8.8 4.1 3 1 1 4 4 4 4 Polycystin cation channel EF-hand_6 PF13405.6 RLN86481.1 - 8.2e-08 31.6 0.1 0.0054 16.6 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RLN86481.1 - 5.4e-06 25.6 4.8 0.0077 15.7 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 RLN86481.1 - 6e-06 26.0 0.3 1.6e-05 24.6 0.1 1.9 1 1 0 1 1 1 1 EF-hand domain pair DUF711 PF05167.12 RLN86481.1 - 0.019 13.9 0.1 0.05 12.5 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) Shisa PF13908.6 RLN86481.1 - 0.041 14.1 0.4 14 5.9 0.0 2.9 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator DUF2973 PF11189.8 RLN86481.1 - 0.11 12.6 2.4 6.1 7.0 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) TssO PF17561.2 RLN86481.1 - 0.14 12.2 0.7 11 6.1 0.0 2.7 2 0 0 2 2 2 0 Type VI secretion system, TssO Pho86 PF11124.8 RLN86481.1 - 0.22 10.9 3.2 4.3 6.7 0.1 3.6 4 0 0 4 4 4 0 Inorganic phosphate transporter Pho86 FYVE PF01363.21 RLN86482.1 - 1e-15 57.6 5.8 1.9e-15 56.7 5.8 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN86482.1 - 0.057 13.6 7.2 0.035 14.3 5.1 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger START PF01852.19 RLN86483.1 - 1.7e-14 53.7 0.2 4.5e-14 52.4 0.2 1.7 1 0 0 1 1 1 1 START domain PDZ PF00595.24 RLN86483.1 - 0.0023 18.2 0.0 0.008 16.5 0.0 1.8 2 0 0 2 2 2 1 PDZ domain DUF5421 PF17458.2 RLN86483.1 - 0.017 14.5 0.1 0.032 13.6 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5421) Fe_dep_repr_C PF02742.15 RLN86483.1 - 0.096 12.8 0.0 0.38 10.9 0.0 2.0 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain DUF953 PF06110.11 RLN86484.1 - 8.1e-33 112.6 0.0 2e-22 79.0 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF953) Glutaredoxin PF00462.24 RLN86484.1 - 0.035 14.3 0.1 3.2 8.1 0.0 2.6 2 0 0 2 2 2 0 Glutaredoxin DUF953 PF06110.11 RLN86485.1 - 5.1e-21 74.5 0.0 7.6e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF953) DUF953 PF06110.11 RLN86486.1 - 6.6e-20 70.9 0.0 8.3e-09 35.1 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF953) PPR_2 PF13041.6 RLN86487.1 - 4.8e-07 29.9 0.0 0.24 11.6 0.0 5.9 5 1 1 6 6 6 1 PPR repeat family PPR PF01535.20 RLN86487.1 - 4.1e-06 26.7 0.1 3.3 8.2 0.0 6.4 7 0 0 7 7 7 1 PPR repeat PPR_long PF17177.4 RLN86487.1 - 1.2e-05 24.8 1.0 0.12 11.7 0.1 3.2 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP Smr PF01713.21 RLN86487.1 - 5.5e-05 23.4 0.0 0.00014 22.1 0.0 1.7 1 0 0 1 1 1 1 Smr domain DUF953 PF06110.11 RLN86488.1 - 1.9e-24 85.5 0.0 1.7e-12 47.0 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF953) C2 PF00168.30 RLN86489.1 - 4.6e-06 26.9 0.0 8.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain Serglycin PF04360.12 RLN86489.1 - 7.7 6.5 7.6 21 5.0 7.3 1.8 1 1 0 1 1 1 0 Serglycin PH PF00169.29 RLN86490.1 - 1e-25 90.3 0.1 1.7e-16 60.6 0.0 3.1 3 0 0 3 3 3 2 PH domain VPS9 PF02204.18 RLN86490.1 - 2e-13 50.4 0.1 3.3e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PDZ PF00595.24 RLN86490.1 - 2.5e-08 34.1 0.0 7.2e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PH_8 PF15409.6 RLN86490.1 - 1.6e-07 31.5 0.4 0.00042 20.5 0.0 2.8 2 0 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 RLN86490.1 - 1.4e-06 28.3 0.0 0.073 13.2 0.0 2.5 2 0 0 2 2 2 2 PH domain PDZ_6 PF17820.1 RLN86490.1 - 4.7e-05 23.1 0.2 0.00012 21.9 0.2 1.7 1 0 0 1 1 1 1 PDZ domain PH_11 PF15413.6 RLN86490.1 - 9.9e-05 22.7 1.0 0.094 13.1 0.6 3.6 2 1 0 2 2 2 1 Pleckstrin homology domain PDZ_2 PF13180.6 RLN86490.1 - 0.026 14.9 0.1 0.067 13.5 0.1 1.7 1 0 0 1 1 1 0 PDZ domain PH_6 PF15406.6 RLN86490.1 - 0.026 14.8 0.0 8.9 6.6 0.0 2.8 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3381 PF11861.8 RLN86490.1 - 2 8.2 7.8 3.7 7.3 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) IMPDH PF00478.25 RLN86491.1 - 9.8e-134 445.7 3.3 1.1e-133 445.5 3.3 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 RLN86491.1 - 9.2e-14 51.6 0.1 1e-06 29.0 0.0 3.4 3 0 0 3 3 3 2 CBS domain NMO PF03060.15 RLN86491.1 - 2.7e-09 36.9 1.2 8.3e-07 28.7 1.4 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 RLN86491.1 - 4.3e-08 32.6 0.7 7.9e-08 31.7 0.7 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 RLN86491.1 - 3.3e-05 23.5 1.5 0.00011 21.7 1.5 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 RLN86491.1 - 0.00053 19.4 1.0 0.0012 18.2 1.0 1.6 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DUF561 PF04481.12 RLN86491.1 - 0.011 15.0 1.1 0.14 11.3 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF561) NanE PF04131.14 RLN86491.1 - 0.11 11.7 0.9 0.64 9.2 0.9 2.4 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase G3P_antiterm PF04309.12 RLN86491.1 - 0.15 11.4 0.3 0.78 9.1 0.1 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Dus PF01207.17 RLN86491.1 - 0.21 10.6 0.5 0.49 9.4 0.0 1.8 3 0 0 3 3 3 0 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 RLN86491.1 - 0.22 10.7 2.1 0.23 10.6 0.4 1.9 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase GDP_Man_Dehyd PF16363.5 RLN86492.1 - 1.3e-145 485.0 0.0 1.5e-145 484.7 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RLN86492.1 - 7.4e-68 228.6 0.0 9.4e-68 228.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 RLN86492.1 - 8e-06 25.2 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RLN86492.1 - 0.013 14.6 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ank_2 PF12796.7 RLN86493.1 - 1.6e-42 144.0 21.5 1.5e-08 35.1 0.2 7.0 2 2 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN86493.1 - 3.2e-37 126.4 22.9 1.1e-06 29.1 0.0 10.5 7 4 3 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN86493.1 - 1.4e-33 114.5 34.1 0.00021 21.5 0.3 15.0 4 3 11 15 15 15 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN86493.1 - 3.9e-18 63.7 11.5 5.5 7.9 0.0 13.9 15 1 1 16 16 16 4 Ankyrin repeat Ank PF00023.30 RLN86493.1 - 1.4e-05 25.3 5.0 60 4.3 0.0 8.7 6 4 3 9 9 9 0 Ankyrin repeat DUF5049 PF16468.5 RLN86493.1 - 8.7e-05 22.3 0.1 68 3.5 0.0 7.1 3 2 4 7 7 7 0 Domain of unknown function (DUF5049) ABC_tran PF00005.27 RLN86496.1 - 1.4e-46 158.4 0.0 5.9e-24 85.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 RLN86496.1 - 4.5e-22 79.0 28.8 1.9e-13 50.7 10.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region Dynamin_N PF00350.23 RLN86496.1 - 3.6e-06 27.2 0.0 0.015 15.3 0.0 2.4 2 0 0 2 2 2 2 Dynamin family AAA_16 PF13191.6 RLN86496.1 - 4.2e-06 27.3 0.6 0.008 16.6 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 RLN86496.1 - 1.5e-05 25.0 0.1 0.22 11.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 RLN86496.1 - 2e-05 24.2 1.2 0.13 12.0 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 RLN86496.1 - 2.5e-05 23.8 2.6 0.5 9.8 0.0 4.0 2 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 RLN86496.1 - 4.4e-05 23.7 0.2 0.11 12.7 0.1 3.3 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RLN86496.1 - 5.6e-05 23.4 2.4 0.83 9.9 0.2 3.5 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 RLN86496.1 - 5.9e-05 23.0 3.8 0.039 13.9 0.2 3.4 3 0 0 3 3 3 1 NACHT domain RsgA_GTPase PF03193.16 RLN86496.1 - 7e-05 22.8 0.1 0.024 14.5 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase IstB_IS21 PF01695.17 RLN86496.1 - 0.00029 20.6 0.1 2.9 7.6 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_25 PF13481.6 RLN86496.1 - 0.0006 19.4 0.0 0.087 12.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 RLN86496.1 - 0.00064 19.9 2.4 0.028 14.5 0.2 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_23 PF13476.6 RLN86496.1 - 0.00078 20.0 0.1 0.32 11.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 RLN86496.1 - 0.0035 16.7 1.3 1 8.7 0.1 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family RNA_helicase PF00910.22 RLN86496.1 - 0.0041 17.5 0.0 0.65 10.4 0.0 2.7 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.22 RLN86496.1 - 0.0055 15.9 1.1 0.4 9.8 0.1 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.6 RLN86496.1 - 0.0088 15.8 1.1 0.13 12.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 RLN86496.1 - 0.01 16.0 0.0 0.41 10.9 0.0 3.4 4 0 0 4 4 3 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 RLN86496.1 - 0.014 14.6 0.0 3.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Viral_helicase1 PF01443.18 RLN86496.1 - 0.017 14.9 0.1 0.11 12.2 0.1 2.3 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 RLN86496.1 - 0.025 15.1 0.3 8.4 7.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.6 RLN86496.1 - 0.052 13.3 2.0 2.8 7.6 0.0 3.4 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 RLN86496.1 - 0.055 12.5 0.2 10 5.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2075 PF09848.9 RLN86496.1 - 0.062 12.5 1.1 0.41 9.8 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 RLN86496.1 - 0.14 11.8 0.0 7.5 6.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 RLN86496.1 - 0.21 11.1 0.9 2.8 7.5 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 RLN86496.1 - 0.21 10.7 0.2 7.1 5.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 RLN86496.1 - 0.24 10.9 0.4 18 4.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AIG1 PF04548.16 RLN86496.1 - 3 7.1 4.1 23 4.2 0.2 3.0 3 0 0 3 3 3 0 AIG1 family Hydrolase_4 PF12146.8 RLN86497.1 - 2.7e-41 141.4 0.0 7e-41 140.1 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN86497.1 - 1.1e-11 45.8 1.0 1.5e-11 45.3 1.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 RLN86497.1 - 1.4e-05 24.7 0.1 0.0031 17.0 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 RLN86497.1 - 2.5e-05 24.1 0.5 0.00076 19.2 0.5 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 RLN86497.1 - 0.0011 18.5 0.0 0.08 12.5 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 RLN86497.1 - 0.019 14.8 0.1 8.7 6.1 0.0 3.1 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 RLN86497.1 - 0.053 13.2 0.2 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_9 PF10081.9 RLN86497.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Hydrolase_4 PF12146.8 RLN86498.1 - 1.7e-39 135.5 0.0 2e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN86498.1 - 6.4e-09 36.7 0.5 9.6e-09 36.2 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN86498.1 - 0.0014 18.3 0.3 0.61 9.7 0.4 2.3 2 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN86498.1 - 0.015 14.8 0.1 3.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 RLN86498.1 - 0.21 11.3 0.3 19 4.9 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 RLN86499.1 - 1e-42 146.0 0.0 1.3e-26 93.3 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN86499.1 - 8.1e-07 29.9 1.0 1.3e-06 29.2 1.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN86499.1 - 0.004 16.8 3.1 1.3 8.6 0.1 3.3 2 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN86499.1 - 0.013 14.9 0.0 4.5 6.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 RLN86500.1 - 8.2e-43 146.4 0.1 1.7e-26 93.0 0.0 2.5 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN86500.1 - 8.4e-07 29.8 3.0 1.3e-06 29.2 3.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN86500.1 - 0.00068 19.4 0.8 1.3 8.6 0.1 3.2 3 0 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN86500.1 - 0.0082 15.6 0.1 2.2 7.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 RLN86502.1 - 4.6e-45 153.8 0.0 5.4e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN86502.1 - 2.1e-12 48.1 0.4 3e-12 47.6 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN86502.1 - 9e-05 22.2 0.2 0.014 15.1 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN86502.1 - 0.00033 20.2 0.1 0.099 12.1 0.1 2.4 3 0 0 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.18 RLN86502.1 - 0.0053 16.3 0.0 0.6 9.6 0.1 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Esterase PF00756.20 RLN86502.1 - 0.067 12.8 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 RLN86502.1 - 0.12 12.2 0.1 17 5.1 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Methyltransf_PK PF05891.12 RLN86503.1 - 5.5e-71 238.5 0.0 6.7e-71 238.3 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 RLN86503.1 - 3.8e-08 33.9 0.0 3e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN86503.1 - 6.7e-07 29.9 0.0 1.5e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 RLN86503.1 - 1.9e-06 27.3 0.0 3.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 RLN86503.1 - 4.3e-05 24.2 0.0 0.00012 22.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN86503.1 - 0.00017 21.5 0.0 0.00054 19.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Rsm22 PF09243.10 RLN86503.1 - 0.0054 16.0 0.0 0.0085 15.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_31 PF13847.6 RLN86503.1 - 0.18 11.6 0.0 0.86 9.4 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Aquarius_N PF16399.5 RLN86504.1 - 9.2e-117 391.1 10.0 2.9e-68 230.7 0.0 2.4 3 0 0 3 3 3 2 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 RLN86504.1 - 9.2e-31 107.0 0.0 1.7e-30 106.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RLN86504.1 - 7.4e-28 98.0 0.0 4.4e-27 95.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain Lactamase_B PF00753.27 RLN86504.1 - 2.7e-10 40.6 0.1 9.8e-10 38.8 0.1 2.0 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily cNMP_binding PF00027.29 RLN86504.1 - 5e-09 36.1 0.0 1.2 9.3 0.0 5.1 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain AAA_30 PF13604.6 RLN86504.1 - 8.3e-07 28.9 2.7 0.011 15.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain Lactamase_B_2 PF12706.7 RLN86504.1 - 3.6e-06 26.6 0.1 8.7e-06 25.4 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain AAA_19 PF13245.6 RLN86504.1 - 2.9e-05 24.4 0.1 0.0031 17.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain UvrD_C_2 PF13538.6 RLN86504.1 - 0.0017 18.2 0.2 0.0038 17.0 0.2 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain EF-hand_6 PF13405.6 RLN86504.1 - 0.003 17.4 0.0 0.015 15.2 0.0 2.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 RLN86504.1 - 0.0032 17.3 0.7 0.0076 16.1 0.7 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 RLN86504.1 - 0.0036 17.7 1.3 0.011 16.2 1.3 1.9 1 0 0 1 1 1 1 EF-hand domain pair UvrD-helicase PF00580.21 RLN86504.1 - 0.004 16.7 1.3 0.014 15.0 0.0 2.5 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain EF-hand_1 PF00036.32 RLN86504.1 - 0.0042 16.5 0.7 0.013 15.0 0.7 1.9 1 0 0 1 1 1 1 EF hand AAA_16 PF13191.6 RLN86504.1 - 0.015 15.7 1.4 0.06 13.7 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain ResIII PF04851.15 RLN86504.1 - 0.035 14.1 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RLN86504.1 - 0.05 13.9 0.0 0.2 11.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 RLN86504.1 - 0.067 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) EF-hand_5 PF13202.6 RLN86504.1 - 0.17 11.4 0.3 0.43 10.2 0.3 1.7 1 0 0 1 1 1 0 EF hand EF-hand_10 PF14788.6 RLN86504.1 - 0.29 11.0 0.7 0.71 9.8 0.1 1.9 2 0 0 2 2 2 0 EF hand Sds3 PF08598.11 RLN86505.1 - 2.5e-07 31.0 6.3 2.5e-07 31.0 6.3 2.2 1 1 0 2 2 2 1 Sds3-like TT_ORF2 PF02957.15 RLN86505.1 - 3.2 8.7 12.5 0.46 11.4 6.9 2.4 2 0 0 2 2 2 0 TT viral ORF2 eIF-3_zeta PF05091.12 RLN86505.1 - 5.6 5.8 12.0 8 5.3 12.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DAZAP2 PF11029.8 RLN86506.1 - 1.4 9.9 7.0 8 7.4 0.1 2.5 2 0 0 2 2 2 0 DAZ associated protein 2 (DAZAP2) RCDG1 PF15725.5 RLN86506.1 - 3.4 8.2 9.5 2.3 8.7 0.4 2.7 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein TFIIA PF03153.13 RLN86507.1 - 0.98 9.3 11.6 1.8 8.4 11.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DSPn PF14671.6 RLN86508.1 - 1.7e-17 64.2 0.0 2.9e-16 60.2 0.0 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 RLN86508.1 - 2.2e-16 59.9 0.0 5.9e-16 58.5 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RLN86508.1 - 8e-06 25.6 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 RLN86508.1 - 0.014 15.6 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate PRO8NT PF08082.11 RLN86508.1 - 0.045 13.7 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain Y_phosphatase3 PF13350.6 RLN86508.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family PX PF00787.24 RLN86509.1 - 6.7e-08 32.5 0.0 1.3e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 PX domain BSP_II PF05432.11 RLN86509.1 - 0.027 14.2 10.2 0.038 13.7 10.2 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CUE PF02845.16 RLN86509.1 - 0.036 13.8 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 CUE domain EF-hand_5 PF13202.6 RLN86509.1 - 0.13 11.8 0.0 11 5.7 0.0 2.7 2 0 0 2 2 2 0 EF hand ABC_tran PF00005.27 RLN86511.1 - 2.2e-10 41.2 0.1 9.6e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 RLN86511.1 - 0.00018 21.0 0.0 0.00021 20.8 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain 5_nucleotid_C PF02872.18 RLN86512.1 - 2.7e-20 73.2 0.0 1.7e-19 70.6 0.0 2.2 1 1 1 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 RLN86512.1 - 2.6e-10 41.2 0.2 1.7e-09 38.4 0.1 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Ank_2 PF12796.7 RLN86516.1 - 2e-21 76.4 6.7 7.8e-08 32.8 0.2 6.2 4 2 2 7 7 7 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN86516.1 - 7.1e-20 71.1 24.8 6.7e-07 29.7 0.3 10.2 7 4 3 10 10 10 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN86516.1 - 1e-13 51.2 20.5 0.015 15.6 0.2 10.3 8 2 4 12 12 12 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN86516.1 - 4.4e-10 38.9 7.9 11 6.9 0.0 10.2 11 0 0 11 11 11 2 Ankyrin repeat DUF5049 PF16468.5 RLN86516.1 - 9.3e-05 22.3 1.1 2.3 8.2 0.0 5.7 6 1 1 7 7 7 2 Domain of unknown function (DUF5049) DUF676 PF05057.14 RLN86517.1 - 0.044 13.3 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF4307 PF14155.6 RLN86517.1 - 0.11 12.4 5.2 0.19 11.6 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) DUF3357 PF11837.8 RLN86517.1 - 0.46 11.0 2.5 3 8.4 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) Corona_nucleoca PF00937.18 RLN86517.1 - 6.2 5.7 6.0 14 4.6 6.0 1.5 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Ank_2 PF12796.7 RLN86518.1 - 5.7e-37 126.2 2.3 6.9e-10 39.4 0.6 6.9 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN86518.1 - 5.7e-28 96.9 18.3 0.0068 17.0 0.0 11.4 6 3 6 12 12 12 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN86518.1 - 2.9e-27 94.4 18.3 0.34 11.3 0.0 13.8 8 4 7 15 15 15 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN86518.1 - 1.6e-22 77.2 6.4 0.84 10.4 0.0 14.1 15 0 0 15 15 15 4 Ankyrin repeat Ank PF00023.30 RLN86518.1 - 1.9e-06 28.1 8.8 18 6.0 0.0 9.8 8 2 3 11 11 11 2 Ankyrin repeat SKN1 PF03935.15 RLN86519.1 - 2.7e-61 207.5 13.3 1.6e-39 135.7 8.8 4.8 2 2 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Pyr_redox_2 PF07992.14 RLN86521.1 - 5.3e-65 219.6 2.7 7.7e-65 219.0 2.7 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 RLN86521.1 - 2.2e-31 108.4 1.7 2.2e-31 108.4 1.7 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 RLN86521.1 - 1.4e-21 76.8 4.4 3.9e-18 65.8 0.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RLN86521.1 - 6.1e-14 52.0 1.9 4.6e-13 49.1 1.9 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RLN86521.1 - 2.8e-07 30.2 0.4 1.6e-05 24.5 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 RLN86521.1 - 1.1e-06 27.6 2.3 0.00067 18.5 0.5 2.8 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_2 PF00890.24 RLN86521.1 - 5.9e-06 25.6 7.2 5.6e-05 22.4 1.3 3.3 3 1 1 4 4 4 1 FAD binding domain DAO PF01266.24 RLN86521.1 - 2e-05 24.4 7.9 0.002 17.8 1.1 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 RLN86521.1 - 7.3e-05 22.1 0.1 0.00078 18.7 0.1 2.2 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 RLN86521.1 - 0.0004 20.6 0.5 0.00099 19.3 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 RLN86521.1 - 0.0017 17.5 0.5 0.0033 16.6 0.5 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 RLN86521.1 - 0.0025 17.1 0.7 0.0061 15.8 0.7 1.7 1 0 0 1 1 1 1 Thi4 family NAD_binding_7 PF13241.6 RLN86521.1 - 0.05 14.1 1.2 2.5 8.6 0.0 2.8 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 RLN86521.1 - 0.12 11.5 2.5 0.2 10.8 1.2 1.9 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.19 RLN86521.1 - 0.24 10.8 4.4 8.5 5.7 0.0 3.1 3 1 1 4 4 4 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 RLN86521.1 - 0.34 11.5 4.3 17 6.1 0.1 3.1 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 RLN86521.1 - 0.36 10.1 6.9 0.39 10.0 0.7 3.1 3 1 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 RLN86521.1 - 0.57 10.0 4.8 2 8.2 0.1 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 RLN86522.1 - 3.3e-11 43.2 0.1 4.3e-11 42.8 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family PX PF00787.24 RLN86524.1 - 9.3e-08 32.0 0.6 0.008 16.1 0.1 2.4 2 0 0 2 2 2 2 PX domain zf-C3HC4_2 PF13923.6 RLN86524.1 - 9.6e-08 31.7 3.2 4.1e-07 29.7 3.2 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN86524.1 - 1.1e-05 25.7 1.8 1.1e-05 25.7 1.8 2.9 3 0 0 3 3 2 1 Ring finger domain zf-rbx1 PF12678.7 RLN86524.1 - 5.5e-05 23.4 0.4 5.5e-05 23.4 0.4 2.9 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RLN86524.1 - 9.9e-05 22.1 2.9 9.9e-05 22.1 2.9 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN86524.1 - 0.00034 20.5 3.4 0.00034 20.5 3.4 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 RLN86524.1 - 0.0039 16.9 0.8 0.0039 16.9 0.8 2.2 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 RLN86524.1 - 0.035 14.0 0.8 0.035 14.0 0.8 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN86524.1 - 0.048 13.7 1.3 0.18 11.9 1.3 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING-like PF08746.11 RLN86524.1 - 0.29 11.5 3.4 1 9.7 3.4 2.0 1 0 0 1 1 1 0 RING-like domain zf-ANAPC11 PF12861.7 RLN86524.1 - 0.36 10.9 4.6 0.25 11.4 1.4 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn-ribbon_8 PF09723.10 RLN86524.1 - 0.37 10.9 5.9 0.12 12.6 0.9 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-C3H2C3 PF17122.5 RLN86524.1 - 9 6.4 8.7 1.6 8.8 3.4 2.4 2 0 0 2 2 2 0 Zinc-finger UPF0242 PF06785.11 RLN86526.1 - 0.00028 21.1 16.1 0.00028 21.1 16.1 5.5 2 1 2 4 4 4 1 Uncharacterised protein family (UPF0242) N-terminus LRR_6 PF13516.6 RLN86526.1 - 0.012 15.6 0.0 3.7 7.8 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeat DUF4988 PF16378.5 RLN86526.1 - 1.1 8.9 3.9 0.52 10.0 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function DASH_Dam1 PF08653.10 RLN86526.1 - 2.5 8.0 3.8 24 4.8 0.1 3.8 3 0 0 3 3 3 0 DASH complex subunit Dam1 Kelch_3 PF13415.6 RLN86527.1 - 2.1e-21 75.7 9.2 5.3e-07 29.8 0.1 7.1 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.6 RLN86527.1 - 2.3e-18 65.9 4.5 7.2e-05 22.7 0.1 6.5 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN86527.1 - 6.5e-18 64.3 0.2 3.6e-05 23.7 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 RLN86527.1 - 2.4e-06 27.6 0.7 3.3 8.1 0.0 5.8 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.25 RLN86527.1 - 0.00064 19.3 0.1 3.1 7.5 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 RLN86527.1 - 0.00066 19.5 0.1 0.1 12.6 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Ephrin_rec_like PF07699.13 RLN86527.1 - 0.087 12.6 36.4 0.21 11.4 1.9 5.8 3 2 3 6 6 6 0 Putative ephrin-receptor like NCD3G PF07562.14 RLN86527.1 - 0.2 11.7 26.3 3 7.9 0.8 5.2 4 1 0 4 4 4 0 Nine Cysteines Domain of family 3 GPCR ABC_tran_Xtn PF12848.7 RLN86528.1 - 1.8e-24 85.6 7.0 3.1e-24 84.8 7.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_tran PF00005.27 RLN86528.1 - 2.1e-22 80.1 0.1 1.2e-21 77.6 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 RLN86528.1 - 6.6e-08 32.7 5.7 1.1e-05 25.5 0.0 2.5 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RLN86528.1 - 2.1e-06 27.4 2.2 0.0045 16.5 0.0 2.5 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MeaB PF03308.16 RLN86528.1 - 0.0003 19.9 1.0 0.0016 17.5 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 RLN86528.1 - 0.0019 18.3 0.0 0.0048 17.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 RLN86528.1 - 0.0023 17.6 0.2 0.0055 16.4 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 RLN86528.1 - 0.0025 17.6 0.0 0.014 15.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain EspB PF05802.11 RLN86528.1 - 0.0067 16.4 0.0 0.015 15.3 0.0 1.5 1 1 0 1 1 1 1 Enterobacterial EspB protein DUF87 PF01935.17 RLN86528.1 - 0.0082 16.3 3.1 0.034 14.2 0.2 2.5 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_18 PF13238.6 RLN86528.1 - 0.013 16.1 0.2 0.64 10.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 RLN86528.1 - 0.02 15.1 0.3 0.3 11.4 0.3 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 RLN86528.1 - 0.031 14.2 0.2 0.08 12.8 0.2 1.6 1 0 0 1 1 1 0 RsgA GTPase Dynamin_N PF00350.23 RLN86528.1 - 0.068 13.2 0.7 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.6 RLN86528.1 - 0.19 11.9 1.5 1 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 RLN86528.1 - 0.25 11.8 5.2 0.26 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 RLN86528.1 - 0.32 10.6 1.7 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase Cellulase PF00150.18 RLN86529.1 - 8.1e-19 68.1 2.4 1.1e-18 67.7 2.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PAN_4 PF14295.6 RLN86529.1 - 9.7e-14 51.0 15.6 1.3e-09 37.8 3.2 3.2 3 0 0 3 3 3 2 PAN domain PAN_2 PF08276.11 RLN86529.1 - 9.4 6.4 22.9 0.31 11.2 1.4 3.5 4 0 0 4 4 4 0 PAN-like domain DUF4954 PF16314.5 RLN86530.1 - 7.4e-42 143.3 0.1 2e-41 141.9 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) HTH_psq PF05225.16 RLN86530.1 - 1.5e-09 37.4 0.2 4.7e-09 35.8 0.2 1.9 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 RLN86530.1 - 0.0031 17.6 0.5 0.0089 16.1 0.5 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 RLN86530.1 - 0.013 16.1 0.8 0.03 15.0 0.8 1.6 1 0 0 1 1 1 0 Homeodomain-like domain PAN_4 PF14295.6 RLN86531.1 - 1.1e-19 70.0 10.9 6.5e-11 42.0 2.4 3.0 2 0 0 2 2 2 2 PAN domain Cellulase PF00150.18 RLN86531.1 - 9.2e-19 67.9 3.1 1.3e-18 67.4 3.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PAN_1 PF00024.26 RLN86531.1 - 1.1e-17 63.8 3.4 1.8e-08 34.2 0.5 2.6 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 RLN86531.1 - 0.056 13.6 10.6 1.9 8.7 1.4 3.4 3 0 0 3 3 3 0 PAN-like domain FYVE PF01363.21 RLN86532.1 - 0.0047 17.0 9.0 0.0077 16.4 9.0 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN86532.1 - 0.35 11.1 4.6 0.67 10.2 4.6 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger DUF2318 PF10080.9 RLN86532.1 - 0.71 10.0 4.1 0.56 10.4 2.5 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2318) FYVE PF01363.21 RLN86533.1 - 0.018 15.2 8.8 0.03 14.5 8.8 1.4 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN86533.1 - 0.26 11.5 5.6 0.53 10.5 5.6 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger CTU2 PF10288.9 RLN86533.1 - 4 7.7 7.6 0.65 10.3 2.2 2.2 1 1 1 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 FYVE PF01363.21 RLN86534.1 - 0.12 12.6 8.5 0.23 11.6 8.5 1.4 1 0 0 1 1 1 0 FYVE zinc finger Abhydrolase_3 PF07859.13 RLN86535.1 - 9.6e-29 100.7 0.0 1.7e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN86535.1 - 3.2e-09 36.1 0.0 4.6e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 RLN86535.1 - 0.096 12.1 0.0 0.84 9.1 0.0 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 RLN86536.1 - 2.5e-30 105.9 0.0 3.8e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN86536.1 - 1.7e-07 30.5 0.0 4.4e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase PNK3P PF08645.11 RLN86536.1 - 0.018 14.7 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase Rot1 PF10681.9 RLN86536.1 - 0.11 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal Abhydrolase_2 PF02230.16 RLN86536.1 - 0.13 12.1 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 RLN86537.1 - 2.7e-28 99.3 0.0 4.7e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN86537.1 - 3.1e-10 39.5 0.0 4.1e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 RLN86537.1 - 0.03 13.8 0.0 0.12 11.9 0.0 2.1 2 1 0 2 2 2 0 Prolyl oligopeptidase family BAAT_C PF08840.11 RLN86537.1 - 0.049 13.5 0.0 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Amidase02_C PF12123.8 RLN86537.1 - 0.18 11.5 0.0 0.62 9.8 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase Pribosyltran_N PF13793.6 RLN86538.1 - 2.4e-50 169.3 0.2 2.5e-49 166.0 0.2 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 RLN86538.1 - 8e-27 94.5 0.2 2.2e-26 93.0 0.2 1.8 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 RLN86538.1 - 7.9e-12 45.0 0.0 2.1e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 RLN86538.1 - 0.017 14.6 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase GATase PF00117.28 RLN86539.1 - 3e-45 154.3 0.1 4.6e-43 147.2 0.0 2.0 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 RLN86539.1 - 0.00025 20.9 1.0 0.0015 18.4 1.0 1.9 1 1 0 1 1 1 1 Peptidase C26 EST1_DNA_bind PF10373.9 RLN86541.1 - 1.4e-28 100.2 0.0 3.4e-28 98.9 0.0 1.7 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain RNase_Zc3h12a PF11977.8 RLN86541.1 - 1.1e-25 90.3 0.0 1.9e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PRORP PF16953.5 RLN86541.1 - 4.5e-06 26.4 0.0 1.2e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 Protein-only RNase P EST1 PF10374.9 RLN86541.1 - 7.4e-05 23.4 0.4 7.4e-05 23.4 0.4 2.7 2 1 0 2 2 2 1 Telomerase activating protein Est1 TPR_16 PF13432.6 RLN86541.1 - 0.092 13.4 0.2 0.62 10.8 0.2 2.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 RLN86541.1 - 0.14 11.9 0.2 0.35 10.6 0.2 1.6 1 0 0 1 1 1 0 TPR repeat TPR_1 PF00515.28 RLN86542.1 - 1.4e-10 40.5 0.7 0.014 15.2 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN86542.1 - 2.3e-09 36.7 6.5 0.0049 16.9 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN86542.1 - 3.1e-08 33.1 0.1 0.29 10.9 0.0 4.1 4 0 0 4 4 4 3 TPR repeat TPR_16 PF13432.6 RLN86542.1 - 3.3e-07 30.8 14.3 0.0015 19.1 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN86542.1 - 4e-07 30.3 13.5 0.0053 17.5 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN86542.1 - 9.8e-07 28.4 2.5 0.049 13.7 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN86542.1 - 0.00011 22.3 1.9 0.24 11.9 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN86542.1 - 0.00021 21.5 12.0 0.096 13.0 0.4 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN86542.1 - 0.00024 21.0 0.3 0.14 12.4 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN86542.1 - 0.0064 17.0 5.9 0.1 13.1 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 RLN86542.1 - 0.012 15.3 0.5 0.049 13.3 0.3 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_10 PF13374.6 RLN86542.1 - 0.018 14.9 9.9 0.21 11.5 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DotD PF16816.5 RLN86542.1 - 0.039 13.9 0.3 0.08 12.9 0.3 1.6 1 0 0 1 1 1 0 DotD protein TPR_5 PF12688.7 RLN86542.1 - 0.085 13.1 6.7 0.39 11.0 3.3 2.8 1 1 1 3 3 3 0 Tetratrico peptide repeat TPR_9 PF13371.6 RLN86542.1 - 3.4 7.9 11.5 0.29 11.3 0.9 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RCC1 PF00415.18 RLN86543.1 - 1.1e-103 339.8 29.1 3.5e-18 66.0 0.6 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN86543.1 - 3.3e-54 179.7 34.6 2.2e-10 40.1 0.2 8.3 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 RLN86543.1 - 1e-25 90.1 0.3 2.9e-25 88.6 0.1 1.8 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 RLN86543.1 - 0.0007 19.7 0.5 0.011 15.8 0.1 2.6 2 1 1 3 3 3 1 BTB And C-terminal Kelch DUF4213 PF13938.6 RLN86543.1 - 0.0082 16.4 8.4 10 6.4 0.0 5.0 4 1 1 5 5 5 2 Putative heavy-metal chelation DUF1921 PF09081.10 RLN86543.1 - 0.12 12.6 0.8 10 6.4 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1921) GCP_N_terminal PF17681.1 RLN86544.1 - 4.4e-72 243.3 0.0 6.2e-72 242.8 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF4455 PF14643.6 RLN86546.1 - 7.1e-44 150.2 18.0 6.9e-34 117.3 7.0 4.1 4 0 0 4 4 4 2 Domain of unknown function (DUF4455) DUF4456 PF14644.6 RLN86546.1 - 6.2e-39 133.9 5.4 6.8e-39 133.7 2.1 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4456) RNA_pol_Rbc25 PF08292.12 RLN86546.1 - 1.5e-13 51.1 0.0 3.8e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 RLN86546.1 - 6.4e-08 32.8 0.1 2.1e-07 31.2 0.1 2.0 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 ABC_tran_CTD PF16326.5 RLN86546.1 - 5 7.5 7.7 8.5 6.7 4.2 3.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain ZT_dimer PF16916.5 RLN86547.1 - 1.8e-08 34.4 0.6 2.7e-08 33.8 0.6 1.2 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Cation_efflux PF01545.21 RLN86547.1 - 3.9e-05 23.5 1.0 5.2e-05 23.1 1.0 1.1 1 0 0 1 1 1 1 Cation efflux family Oxidored_FMN PF00724.20 RLN86549.1 - 8.1e-83 278.5 0.0 9.2e-83 278.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dynein_light PF01221.18 RLN86550.1 - 7.2e-24 83.9 0.2 8.9e-24 83.6 0.2 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Herpes_UL21 PF03252.13 RLN86550.1 - 0.12 11.1 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL21 Syndecan PF01034.20 RLN86551.1 - 0.036 14.0 0.3 0.075 13.0 0.0 1.6 2 0 0 2 2 2 0 Syndecan domain Choline_transpo PF04515.12 RLN86552.1 - 1.2e-38 133.2 15.6 5.2e-38 131.1 12.7 2.3 2 1 0 2 2 2 2 Plasma-membrane choline transporter DUF4059 PF13268.6 RLN86552.1 - 0.4 11.1 5.0 15 6.1 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) ARL2_Bind_BART PF11527.8 RLN86553.1 - 5.1e-10 39.5 0.0 1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Tn7_Tnp_TnsA_C PF08721.11 RLN86553.1 - 0.19 12.4 1.2 1.4 9.6 0.1 2.7 2 1 1 3 3 3 0 TnsA endonuclease C terminal ABC2_membrane_3 PF12698.7 RLN86554.1 - 4.7e-42 144.3 17.5 2.3e-26 92.7 3.9 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 RLN86554.1 - 1.3e-39 135.8 0.0 2.4e-19 70.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter Ribosomal_S28e PF01200.18 RLN86554.1 - 1.9e-28 98.3 0.6 5.4e-28 96.8 0.6 1.9 1 0 0 1 1 1 1 Ribosomal protein S28e AAA_21 PF13304.6 RLN86554.1 - 8.2e-13 48.8 0.1 4.6e-06 26.6 0.0 3.3 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RLN86554.1 - 6.8e-05 22.4 0.0 1.1 8.7 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC2_membrane PF01061.24 RLN86554.1 - 0.021 14.3 31.3 0.01 15.3 12.5 3.6 3 0 0 3 3 3 0 ABC-2 type transporter NB-ARC PF00931.22 RLN86554.1 - 0.029 13.6 0.0 0.06 12.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 RLN86554.1 - 0.058 13.8 0.3 6.9 7.0 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 RLN86554.1 - 0.068 13.1 0.2 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase WD40 PF00400.32 RLN86555.1 - 5.2e-44 147.4 15.0 2.2e-07 31.4 0.2 7.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN86555.1 - 7.9e-10 38.9 0.1 0.35 11.2 0.1 4.6 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 RLN86555.1 - 3.7e-05 22.7 0.0 0.0081 14.9 0.0 3.3 2 1 2 4 4 4 1 Nup133 N terminal like Nup160 PF11715.8 RLN86555.1 - 6e-05 21.9 0.2 0.044 12.4 0.1 3.4 3 1 0 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RLN86555.1 - 0.00018 20.6 0.1 0.0034 16.4 0.0 2.5 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 RLN86555.1 - 0.02 13.2 0.0 0.1 10.9 0.0 1.9 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 RLN86555.1 - 0.079 11.9 0.0 0.52 9.2 0.0 2.1 1 1 2 3 3 3 0 Partner and localizer of BRCA2 WD40 domain EF-hand_7 PF13499.6 RLN86556.1 - 0.068 13.6 0.8 0.46 11.0 0.4 2.6 2 1 0 2 2 2 0 EF-hand domain pair AAA PF00004.29 RLN86557.1 - 2e-38 131.8 0.0 3.9e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RLN86557.1 - 8e-09 35.2 0.1 2.6e-08 33.5 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 RLN86557.1 - 8.3e-06 25.6 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RLN86557.1 - 4e-05 23.9 1.4 0.28 11.4 0.0 3.2 2 1 1 3 3 3 2 AAA domain AAA_14 PF13173.6 RLN86557.1 - 0.003 17.6 0.0 0.0066 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 RLN86557.1 - 0.0032 16.7 0.0 0.0059 15.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 RLN86557.1 - 0.0036 16.7 0.0 0.0076 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 RLN86557.1 - 0.0052 17.2 0.1 0.03 14.7 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 RLN86557.1 - 0.008 15.9 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RLN86557.1 - 0.014 15.8 3.1 0.032 14.6 0.1 2.9 2 2 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 RLN86557.1 - 0.016 15.2 0.1 0.064 13.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 RLN86557.1 - 0.019 15.0 0.0 0.056 13.4 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 RLN86557.1 - 0.019 14.7 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 RLN86557.1 - 0.019 14.5 0.1 0.14 11.7 0.1 2.3 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 RLN86557.1 - 0.023 14.6 0.0 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_2 PF07724.14 RLN86557.1 - 0.026 14.7 0.0 0.066 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) LisH PF08513.11 RLN86557.1 - 0.037 14.0 0.0 0.084 12.9 0.0 1.6 1 0 0 1 1 1 0 LisH DUF815 PF05673.13 RLN86557.1 - 0.061 12.5 0.0 0.45 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 RLN86557.1 - 0.072 13.6 0.1 0.25 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 RLN86557.1 - 0.084 13.0 0.0 0.28 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RLN86557.1 - 0.16 11.5 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region XPG_N PF00752.17 RLN86558.1 - 6.8e-13 49.0 0.0 1.4e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 RLN86558.1 - 2.5e-12 47.0 0.6 7.3e-12 45.5 0.1 2.0 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 RLN86558.1 - 7.3e-06 25.6 0.1 1.6e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 XPG domain containing DUF4817 PF16087.5 RLN86558.1 - 0.061 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) bZIP_1 PF00170.21 RLN86559.1 - 4.8e-05 23.4 5.6 4.8e-05 23.4 5.6 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 RLN86559.1 - 0.00033 20.7 6.9 0.00068 19.7 6.9 1.5 1 0 0 1 1 1 1 Basic region leucine zipper LTXXQ PF07813.12 RLN86559.1 - 0.036 14.8 3.1 0.052 14.3 0.3 2.3 2 0 0 2 2 2 0 LTXXQ motif family protein Csm1_N PF18504.1 RLN86559.1 - 4.5 7.7 6.6 1 9.7 0.3 2.6 3 0 0 3 3 3 0 Csm1 N-terminal domain Isochorismatase PF00857.20 RLN86561.1 - 8.1e-33 114.0 0.6 1e-32 113.8 0.6 1.1 1 0 0 1 1 1 1 Isochorismatase family Aminotran_1_2 PF00155.21 RLN86563.1 - 6.8e-55 186.7 0.0 7.7e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 RLN86563.1 - 0.005 15.4 0.0 0.0078 14.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 RLN86563.1 - 0.007 15.4 0.0 0.01 14.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Nucleoside_tran PF01733.18 RLN86565.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Nucleoside transporter Pkinase_Tyr PF07714.17 RLN86566.1 - 2.5e-49 167.9 0.0 1.5e-41 142.4 0.0 4.0 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 RLN86566.1 - 2.9e-44 151.4 0.0 9.6e-41 139.9 0.0 3.5 4 0 0 4 4 4 2 Protein kinase domain CH PF00307.31 RLN86567.1 - 0.00038 20.6 0.1 0.004 17.3 0.0 2.6 3 0 0 3 3 3 1 Calponin homology (CH) domain CLZ PF16526.5 RLN86567.1 - 1.6 9.2 4.9 1.7 9.1 0.1 3.0 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AA_permease_2 PF13520.6 RLN86569.1 - 7.7e-29 100.8 34.9 1.1e-28 100.2 34.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN86569.1 - 4.8e-16 58.4 29.1 6.7e-16 57.9 29.1 1.1 1 0 0 1 1 1 1 Amino acid permease TPR_19 PF14559.6 RLN86570.1 - 3.3e-06 27.5 5.9 0.015 15.8 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN86570.1 - 2.5e-05 24.8 6.5 0.00016 22.3 4.3 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN86570.1 - 8.5e-05 22.2 0.0 0.00017 21.2 0.0 1.5 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 RLN86570.1 - 0.00034 20.5 1.2 1.8 8.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN86570.1 - 0.00058 20.1 0.5 0.13 12.7 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN86570.1 - 0.016 16.0 1.9 0.016 16.0 1.9 3.4 2 2 1 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.10 RLN86570.1 - 0.13 11.2 0.6 0.26 10.3 0.3 1.3 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) FlgN PF05130.12 RLN86570.1 - 0.4 11.2 6.8 0.74 10.3 0.4 2.4 2 0 0 2 2 2 0 FlgN protein Myb_DNA-binding PF00249.31 RLN86571.1 - 6.1e-13 48.7 0.6 1e-12 48.0 0.6 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN86571.1 - 0.12 12.7 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN86571.1 - 0.16 11.9 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 Myb DNA-binding like Ank_4 PF13637.6 RLN86572.1 - 2.7e-30 104.4 5.5 2.2e-09 37.6 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN86572.1 - 2.1e-25 89.1 1.1 1.4e-15 57.7 0.7 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN86572.1 - 1.4e-20 71.2 0.0 0.00017 21.7 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 RLN86572.1 - 1.6e-20 72.9 1.2 1.8e-09 37.7 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN86572.1 - 1.3e-19 69.7 1.8 9.6e-05 22.7 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat RIO1 PF01163.22 RLN86573.1 - 8.2e-39 133.2 0.1 3.5e-38 131.1 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.11 RLN86573.1 - 1.7e-34 117.9 0.2 3.9e-34 116.7 0.2 1.7 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 RLN86573.1 - 0.00011 22.2 0.2 0.00097 19.1 0.1 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family TFIIF_alpha PF05793.12 RLN86573.1 - 0.0073 14.9 12.5 0.01 14.5 12.5 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pkinase PF00069.25 RLN86573.1 - 0.013 14.9 0.1 3.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain SDA1 PF05285.12 RLN86573.1 - 0.34 10.3 15.5 0.23 10.8 13.5 1.6 2 0 0 2 2 2 0 SDA1 BSP_II PF05432.11 RLN86573.1 - 0.36 10.5 17.8 0.54 9.9 17.8 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.14 RLN86573.1 - 0.4 8.9 11.3 0.81 7.9 11.3 1.5 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 RLN86573.1 - 0.47 8.5 20.6 0.75 7.8 20.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Vfa1 PF08432.10 RLN86573.1 - 0.72 10.2 8.2 1.3 9.3 8.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.12 RLN86573.1 - 0.92 7.6 13.3 1.2 7.2 13.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 RLN86573.1 - 6 5.9 22.4 9.3 5.3 22.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DEAD PF00270.29 RLN86574.1 - 5.7e-39 133.7 0.0 1.2e-38 132.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN86574.1 - 8.4e-24 84.1 0.0 3.9e-23 81.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 RLN86574.1 - 1.3e-20 73.4 0.0 2.6e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.6 RLN86574.1 - 0.011 16.0 0.6 0.081 13.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 RLN86574.1 - 0.03 14.3 0.0 0.03 14.3 0.0 3.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Asr PF06392.11 RLN86574.1 - 0.11 12.9 4.8 0.49 10.9 4.8 2.2 1 0 0 1 1 1 0 Acid shock protein repeat DUF572 PF04502.13 RLN86574.1 - 3.2 7.3 31.6 4.3 6.9 31.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) CHGN PF05679.16 RLN86575.1 - 0.014 14.2 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase Ion_trans PF00520.31 RLN86576.1 - 2.3e-191 632.9 47.7 1.3e-49 168.6 0.1 4.1 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 RLN86576.1 - 9.5e-15 54.2 66.1 3.2e-07 29.4 2.6 10.6 8 3 3 11 11 11 8 Polycystin cation channel Ephrin_rec_like PF07699.13 RLN86577.1 - 2e-05 24.2 18.4 4.4e-05 23.2 3.9 35.2 20 10 16 36 36 36 26 Putative ephrin-receptor like adh_short PF00106.25 RLN86578.1 - 1.7e-38 132.1 2.0 3.2e-38 131.2 2.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN86578.1 - 9.1e-28 97.4 2.3 1.8e-27 96.4 2.3 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 RLN86578.1 - 4.3e-05 23.1 0.4 7.7e-05 22.3 0.4 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 RLN86578.1 - 0.00033 20.6 1.7 0.00068 19.6 1.7 1.7 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 RLN86578.1 - 0.069 12.2 0.6 0.18 10.9 0.1 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain DUF2102 PF09875.9 RLN86578.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) PQQ PF01011.21 RLN86579.1 - 1.9e-06 27.5 1.2 8.8e-06 25.4 0.1 2.6 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_2 PF13360.6 RLN86579.1 - 0.002 17.8 1.2 0.19 11.3 0.3 2.7 2 1 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 RLN86579.1 - 0.0082 16.6 2.5 3.4 8.3 0.6 4.6 4 0 0 4 4 4 1 PQQ-like domain WD40 PF00400.32 RLN86581.1 - 9e-44 146.6 18.2 1.9e-07 31.6 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN86581.1 - 8.8e-12 45.2 0.4 0.31 11.4 0.1 5.2 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RLN86581.1 - 2.5e-06 27.5 0.0 0.00053 19.9 0.0 2.9 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 RLN86581.1 - 7.5e-05 21.8 0.2 6.2 5.7 0.0 4.1 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 RLN86581.1 - 0.00031 19.4 0.8 0.0029 16.2 0.1 2.4 1 1 1 2 2 2 1 Cytochrome D1 heme domain Str_synth PF03088.16 RLN86581.1 - 0.17 12.0 0.0 0.68 10.1 0.0 1.9 1 1 1 2 2 2 0 Strictosidine synthase PQQ_3 PF13570.6 RLN86581.1 - 0.7 10.5 3.4 16 6.1 0.2 3.8 2 1 1 3 3 3 0 PQQ-like domain Hanta_nucleocap PF00846.18 RLN86584.1 - 0.0021 16.6 0.1 0.0029 16.1 0.1 1.1 1 0 0 1 1 1 1 Hantavirus nucleocapsid protein RPA_interact_M PF14767.6 RLN86584.1 - 0.032 14.8 0.9 1.6 9.4 0.4 2.6 2 1 0 2 2 2 0 Replication protein A interacting middle Pkinase_Tyr PF07714.17 RLN86585.1 - 1.4e-55 188.4 0.0 2.1e-42 145.2 0.0 3.4 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 RLN86585.1 - 6.1e-51 173.3 0.0 1.4e-38 132.8 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Ank_2 PF12796.7 RLN86585.1 - 1.7e-33 115.1 2.4 1.2e-10 41.8 0.2 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN86585.1 - 1.6e-31 108.3 0.5 1.2e-08 35.3 0.1 5.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN86585.1 - 1.2e-21 76.4 5.4 3.2e-06 27.3 0.3 6.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 RLN86585.1 - 2.4e-21 75.2 8.2 4.9e-05 23.6 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 RLN86585.1 - 1.3e-19 68.2 3.7 0.037 14.6 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Kinase-like PF14531.6 RLN86585.1 - 0.0029 17.0 0.0 0.82 8.9 0.0 3.1 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 RLN86585.1 - 0.0047 15.8 0.0 0.0083 14.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PK PF00224.21 RLN86588.1 - 8.5e-145 482.0 1.0 2.1e-144 480.7 0.3 1.9 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain PK_C PF02887.16 RLN86588.1 - 2.3e-28 98.8 0.2 5.7e-28 97.5 0.2 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 RLN86588.1 - 0.00078 18.6 0.1 0.0018 17.5 0.1 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family CBM_20 PF00686.19 RLN86589.1 - 1.5e-05 24.8 0.0 0.00071 19.4 0.0 2.0 1 1 0 1 1 1 1 Starch binding domain PK PF00224.21 RLN86590.1 - 1.7e-72 244.2 2.2 7.7e-72 242.1 0.8 2.0 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain PK_C PF02887.16 RLN86590.1 - 8.3e-31 106.7 1.0 1.8e-30 105.5 1.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 RLN86590.1 - 0.0028 16.8 0.4 0.03 13.5 0.0 2.2 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Staph_opine_DH PF10100.9 RLN86590.1 - 0.025 13.2 0.0 0.034 12.8 0.0 1.1 1 0 0 1 1 1 0 Staphylopine dehydrogenase Ku_PK_bind PF08785.11 RLN86590.1 - 0.17 12.0 0.0 0.36 11.0 0.0 1.7 1 1 0 1 1 1 0 Ku C terminal domain like BLOC1_2 PF10046.9 RLN86591.1 - 0.0036 17.6 6.9 0.0036 17.6 6.9 1.8 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 gpW PF02831.15 RLN86591.1 - 0.0095 15.8 10.2 1.2 9.1 0.1 4.2 4 1 1 5 5 5 2 gpW POTRA_2 PF08479.11 RLN86591.1 - 0.086 12.7 1.9 0.37 10.7 0.1 2.6 2 0 0 2 2 2 0 POTRA domain, ShlB-type GAS PF13851.6 RLN86591.1 - 0.092 12.1 16.5 0.11 11.8 10.5 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding IZUMO PF15005.6 RLN86591.1 - 0.52 10.8 6.5 8.5 6.9 5.0 2.2 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Borealin PF10512.9 RLN86591.1 - 0.53 10.3 0.0 0.53 10.3 0.0 2.8 3 1 0 4 4 4 0 Cell division cycle-associated protein 8 DivIC PF04977.15 RLN86591.1 - 3.3 7.6 20.7 11 5.9 0.7 3.5 2 1 1 3 3 3 0 Septum formation initiator KLRAQ PF10205.9 RLN86591.1 - 4.4 7.6 16.8 0.11 12.7 8.6 2.4 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein DUF641 PF04859.12 RLN86591.1 - 4.8 7.5 16.7 7.4 6.9 0.3 3.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.10 RLN86591.1 - 4.9 7.3 11.5 13 5.9 0.2 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Sulfate_transp PF00916.20 RLN86592.1 - 0.1 11.3 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 Sulfate permease family DUF2791 PF10923.8 RLN86594.1 - 0.08 11.8 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) SNF2_N PF00176.23 RLN86595.1 - 1.7e-12 46.7 0.0 2.2e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 RLN86595.1 - 2.7e-05 24.2 0.0 3.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit 2-oxoacid_dh PF00198.23 RLN86596.1 - 1.2e-66 224.6 0.1 1.6e-66 224.1 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 RLN86596.1 - 6.3e-28 96.4 7.5 1.5e-13 50.4 0.2 2.6 2 0 0 2 2 2 2 Biotin-requiring enzyme HlyD_3 PF13437.6 RLN86596.1 - 1e-05 26.1 10.1 0.017 15.8 0.7 3.6 2 1 1 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 RLN86596.1 - 0.00035 20.3 3.8 0.0026 17.5 0.3 3.1 2 1 1 3 3 3 1 Biotin-lipoyl like GCV_H PF01597.19 RLN86596.1 - 0.0016 18.3 2.7 0.49 10.3 0.4 2.6 2 1 0 2 2 2 2 Glycine cleavage H-protein RnfC_N PF13375.6 RLN86596.1 - 0.045 13.7 0.7 5 7.2 0.2 3.0 2 1 0 2 2 2 0 RnfC Barrel sandwich hybrid domain DEC-1_N PF04625.13 RLN86596.1 - 0.58 9.1 15.7 0.2 10.6 7.2 2.3 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Rib_recp_KP_reg PF05104.12 RLN86596.1 - 3.5 8.7 17.0 0.54 11.3 10.3 2.3 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region DUF3597 PF12200.8 RLN86596.1 - 7.6 7.1 7.2 14 6.2 1.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) SET PF00856.28 RLN86600.1 - 1.4e-10 41.8 0.1 5.5e-09 36.6 0.1 2.2 1 1 0 1 1 1 1 SET domain AWS PF17907.1 RLN86600.1 - 0.28 11.3 6.4 1.3 9.1 6.6 2.0 2 0 0 2 2 2 0 AWS domain MULE PF10551.9 RLN86601.1 - 6.2e-18 65.0 0.3 1.2e-17 64.1 0.3 1.5 1 0 0 1 1 1 1 MULE transposase domain SNF2_N PF00176.23 RLN86603.1 - 4.7e-49 167.0 0.0 8.6e-49 166.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ERCC3_RAD25_C PF16203.5 RLN86603.1 - 1 8.5 3.9 1.9 7.7 0.0 2.8 3 0 0 3 3 3 0 ERCC3/RAD25/XPB C-terminal helicase SUZ PF12752.7 RLN86603.1 - 4.7 8.1 7.9 5.7 7.8 1.7 3.1 2 0 0 2 2 2 0 SUZ domain Hc1 PF07432.13 RLN86604.1 - 2.3 8.6 11.3 0.072 13.5 2.1 3.1 2 1 1 3 3 3 0 Histone H1-like protein Hc1 LRR_9 PF14580.6 RLN86605.1 - 0.00011 21.8 0.0 0.00025 20.6 0.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 RLN86605.1 - 0.015 15.7 1.8 0.36 11.3 0.1 3.0 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) IQ PF00612.27 RLN86605.1 - 0.017 14.8 25.9 0.29 11.0 0.3 6.0 5 0 0 5 5 5 0 IQ calmodulin-binding motif LRR_8 PF13855.6 RLN86605.1 - 0.17 11.7 1.0 1.8 8.4 0.6 2.5 1 1 2 3 3 3 0 Leucine rich repeat MukB PF04310.12 RLN86605.1 - 0.54 10.0 7.4 0.45 10.3 0.8 2.4 1 1 0 2 2 2 0 MukB N-terminal Myosin_head PF00063.21 RLN86606.1 - 7.7e-187 622.6 0.0 3e-145 485.1 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) FYVE PF01363.21 RLN86606.1 - 1e-16 60.8 6.7 2.2e-16 59.7 6.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger IQ PF00612.27 RLN86606.1 - 1.1e-09 37.2 23.1 0.085 12.7 0.4 6.4 5 0 0 5 5 5 5 IQ calmodulin-binding motif T2SSE PF00437.20 RLN86606.1 - 0.014 14.4 0.0 0.036 13.1 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 RLN86606.1 - 0.019 15.3 0.0 0.06 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RLN86606.1 - 0.14 12.6 10.3 0.21 11.9 0.0 3.3 2 1 1 3 3 3 0 AAA ATPase domain zf-CRD PF17979.1 RLN86606.1 - 1.3 9.1 4.9 3.1 7.9 4.9 1.6 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions C5HCH PF17982.1 RLN86606.1 - 1.9 8.7 6.4 4.5 7.5 6.4 1.6 1 0 0 1 1 1 0 NSD Cys-His rich domain zf-AN1 PF01428.16 RLN86606.1 - 6.3 7.1 9.3 14 5.9 9.3 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger OsmC PF02566.19 RLN86609.1 - 0.033 14.6 0.1 0.26 11.8 0.1 2.5 2 0 0 2 2 2 0 OsmC-like protein ABC2_membrane PF01061.24 RLN86610.1 - 1.2e-06 28.1 6.2 1.2e-06 28.1 6.2 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 RLN86610.1 - 0.035 13.2 3.8 0.038 13.1 3.8 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF659 PF04937.15 RLN86611.1 - 5.9e-11 42.5 0.0 9.7e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 RLN86611.1 - 1.6e-05 24.6 0.0 3.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4780 PF16012.5 RLN86611.1 - 0.068 12.6 0.1 0.19 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4780) Pribosyltran_N PF13793.6 RLN86612.1 - 1e-27 96.4 0.3 1.3e-27 96.1 0.3 1.0 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase PIF1 PF05970.14 RLN86613.1 - 8.2e-10 38.4 0.4 1.2e-09 37.9 0.4 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 RLN86613.1 - 1.6e-07 31.8 0.3 3.1e-07 30.8 0.3 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RLN86613.1 - 2.6e-07 30.5 0.7 4.3e-07 29.8 0.7 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RLN86613.1 - 0.0043 17.3 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RLN86613.1 - 0.015 15.7 0.2 0.04 14.3 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 RLN86613.1 - 0.048 14.1 0.1 0.13 12.7 0.1 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.25 RLN86615.1 - 8.3e-50 169.6 0.0 8.2e-40 136.8 0.0 3.0 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN86615.1 - 9.7e-48 162.7 0.0 2.2e-40 138.6 0.0 3.3 2 1 0 2 2 2 2 Protein tyrosine kinase Ank_2 PF12796.7 RLN86615.1 - 3.5e-31 107.6 3.3 1.6e-10 41.4 0.2 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN86615.1 - 1.5e-29 102.0 4.7 4e-08 33.6 0.1 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN86615.1 - 2.6e-21 73.4 0.4 0.019 15.4 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 RLN86615.1 - 6e-21 73.9 6.3 0.00037 20.8 0.0 6.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 RLN86615.1 - 7.1e-20 70.8 4.5 4.3e-07 30.1 0.1 5.6 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Pkinase_fungal PF17667.1 RLN86615.1 - 0.00018 20.4 0.0 0.00086 18.2 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 RLN86615.1 - 0.029 14.0 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 RLN86615.1 - 0.033 14.1 0.2 0.033 14.1 0.2 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family Zip PF02535.22 RLN86616.1 - 1.6e-28 99.9 10.0 5.1e-28 98.3 10.0 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter MtrG PF04210.13 RLN86616.1 - 3 7.7 6.0 0.31 10.9 0.5 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF2721 PF11026.8 RLN86616.1 - 7.4 6.5 19.5 2.8 7.8 2.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Zip PF02535.22 RLN86617.1 - 2e-17 63.5 22.0 1.9e-10 40.5 6.6 3.0 2 1 1 3 3 3 3 ZIP Zinc transporter DUF2721 PF11026.8 RLN86617.1 - 6.1 6.8 19.0 0.26 11.2 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) CTD_bind PF04818.13 RLN86618.1 - 1.2e-08 35.7 0.0 5.7e-08 33.5 0.0 2.3 1 0 0 1 1 1 1 RNA polymerase II-binding domain. PanZ PF12568.8 RLN86618.1 - 0.026 14.3 0.2 0.088 12.5 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ Tub PF01167.18 RLN86619.1 - 1e-89 300.5 0.0 1.5e-89 299.9 0.0 1.3 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 RLN86619.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) Tetraspanin PF00335.20 RLN86620.1 - 0.0071 16.1 2.5 0.0097 15.6 2.5 1.3 1 0 0 1 1 1 1 Tetraspanin family Tetraspanin PF00335.20 RLN86621.1 - 5.3e-17 62.3 11.1 8.6e-17 61.6 11.1 1.3 1 1 0 1 1 1 1 Tetraspanin family MFS_1 PF07690.16 RLN86621.1 - 2.2e-05 23.6 0.1 5.1e-05 22.4 0.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Pex24p PF06398.11 RLN86621.1 - 0.004 16.2 0.0 0.006 15.6 0.0 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin EphA2_TM PF14575.6 RLN86621.1 - 0.03 15.2 5.7 5.2 8.0 0.0 3.4 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain UPF0239 PF06783.11 RLN86621.1 - 0.074 13.2 1.5 3.8 7.7 0.0 2.9 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0239) LPD1 PF18796.1 RLN86621.1 - 0.11 12.7 0.1 0.94 9.6 0.0 2.4 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 1 TMEM154 PF15102.6 RLN86621.1 - 0.11 12.5 0.1 8.6 6.3 0.1 2.4 2 1 0 2 2 2 0 TMEM154 protein family Comm PF15957.5 RLN86621.1 - 0.65 10.4 3.6 3 8.2 0.1 3.0 2 1 1 3 3 3 0 Commissureless TMEM100 PF16311.5 RLN86621.1 - 0.81 9.3 0.0 0.81 9.3 0.0 2.2 2 1 1 3 3 3 0 Transmembrane protein 100 Cytomega_TRL10 PF06084.11 RLN86621.1 - 1.5 8.9 9.6 0.35 10.9 0.1 2.5 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein ABC2_membrane_2 PF12679.7 RLN86621.1 - 6.6 5.9 8.8 24 4.1 8.8 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein Tetraspanin PF00335.20 RLN86622.1 - 1.4e-18 67.5 6.1 2.1e-18 66.9 6.1 1.3 1 1 0 1 1 1 1 Tetraspanin family Cytomega_TRL10 PF06084.11 RLN86622.1 - 0.00097 19.2 0.1 0.00097 19.2 0.1 2.2 2 0 0 2 2 2 1 Cytomegalovirus TRL10 protein Tetraspanin PF00335.20 RLN86623.1 - 9.6e-14 51.6 9.3 1.2e-13 51.3 9.3 1.1 1 0 0 1 1 1 1 Tetraspanin family Herpes_UL49_5 PF05702.11 RLN86623.1 - 0.046 13.8 0.6 0.046 13.8 0.6 2.0 2 1 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein Comm PF15957.5 RLN86623.1 - 0.05 13.9 2.2 0.28 11.5 0.2 2.5 2 0 0 2 2 2 0 Commissureless Pex24p PF06398.11 RLN86623.1 - 0.12 11.4 0.2 0.22 10.5 0.0 1.5 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF4500 PF14937.6 RLN86623.1 - 0.41 10.7 1.2 1.4 9.0 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4500) Sigma_reg_N PF13800.6 RLN86623.1 - 2.3 8.5 4.8 6.5 7.1 0.1 3.1 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Tetraspanin PF00335.20 RLN86624.1 - 1.4e-09 38.0 7.8 3.3e-09 36.8 7.9 1.6 1 1 0 1 1 1 1 Tetraspanin family DUF4064 PF13273.6 RLN86624.1 - 0.012 15.9 7.6 0.012 15.9 7.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF2385 PF09539.10 RLN86624.1 - 0.041 14.4 0.5 0.099 13.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) DUF2207 PF09972.9 RLN86624.1 - 0.42 9.3 6.3 0.42 9.3 3.0 2.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF202 PF02656.15 RLN86624.1 - 2.1 8.9 11.4 0.6 10.6 2.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Bac_export_2 PF01312.19 RLN86624.1 - 4 6.5 6.4 7.5 5.7 5.2 1.9 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family DUF4191 PF13829.6 RLN86624.1 - 4.4 6.6 9.4 1.5 8.1 0.9 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) c-SKI_SMAD_bind PF08782.10 RLN86625.1 - 0.1 12.8 2.4 0.2 11.9 2.4 1.4 1 0 0 1 1 1 0 c-SKI Smad4 binding domain Phage_Gp23 PF10669.9 RLN86625.1 - 1 9.7 3.1 0.99 9.7 0.8 1.9 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) ARF7EP_C PF14949.6 RLN86625.1 - 7.9 7.1 7.6 1.9 9.2 1.9 2.2 2 0 0 2 2 2 0 ARF7 effector protein C-terminus Peptidase_C2 PF00648.21 RLN86626.1 - 2.1e-10 40.1 0.0 1.1e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 Calpain family cysteine protease Mod_r PF07200.13 RLN86626.1 - 4.2 7.5 10.1 8.1 6.5 0.1 2.9 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein PBP_N PF17093.5 RLN86627.1 - 0.74 10.1 0.0 0.74 10.1 0.0 3.2 3 0 0 3 3 3 0 Penicillin-binding protein N-terminus MCM PF00493.23 RLN86630.1 - 8.6e-99 329.2 0.0 1.2e-98 328.7 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RLN86630.1 - 1.7e-35 121.6 0.1 2.8e-35 120.9 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RLN86630.1 - 3.3e-22 78.7 0.5 9.5e-22 77.2 0.1 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 RLN86630.1 - 5.7e-16 59.0 0.1 1.9e-15 57.3 0.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 RLN86630.1 - 7.7e-09 35.2 0.1 6.2e-07 29.0 0.0 2.6 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI MCM2_N PF12619.8 RLN86630.1 - 1.6e-07 31.7 39.6 1.6e-07 31.7 39.6 3.3 3 1 1 4 4 4 1 Mini-chromosome maintenance protein 2 AAA_5 PF07728.14 RLN86630.1 - 5e-06 26.6 0.0 1.6e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 RLN86630.1 - 4.7e-05 23.2 0.0 0.0088 15.9 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RLN86630.1 - 0.0016 18.2 0.0 0.0061 16.3 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 RLN86630.1 - 0.027 14.9 0.0 0.086 13.3 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-Sec23_Sec24 PF04810.15 RLN86630.1 - 0.033 14.2 0.6 0.063 13.3 0.6 1.5 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger AAA_30 PF13604.6 RLN86630.1 - 0.043 13.5 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain zf-TFIIB PF13453.6 RLN86630.1 - 0.071 12.5 1.2 0.14 11.5 1.2 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger AAA_lid_2 PF17863.1 RLN86630.1 - 5.6 6.9 13.0 0.13 12.1 0.4 3.8 5 0 0 5 5 5 0 AAA lid domain LRR_8 PF13855.6 RLN86631.1 - 2e-05 24.3 2.4 0.084 12.6 1.0 3.4 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 RLN86631.1 - 0.00093 19.5 3.0 0.23 11.9 0.0 3.5 2 2 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RLN86631.1 - 0.095 12.7 0.0 0.18 11.8 0.0 1.4 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 RLN86631.1 - 0.17 11.4 1.7 0.42 10.1 0.8 2.0 2 1 1 3 3 3 0 Leucine-rich repeat KBP_C PF12309.8 RLN86632.1 - 2.9e-78 263.9 0.0 4.6e-78 263.2 0.0 1.3 1 0 0 1 1 1 1 KIF-1 binding protein C terminal GSHPx PF00255.19 RLN86633.1 - 5.9e-27 93.4 0.0 8.1e-27 92.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase DNA_pol_phi PF04931.13 RLN86633.1 - 0.0033 15.6 38.1 0.004 15.4 38.1 1.1 1 0 0 1 1 1 1 DNA polymerase phi SAPS PF04499.15 RLN86633.1 - 0.15 10.8 4.7 0.16 10.7 4.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 RLN86633.1 - 0.35 9.0 28.4 0.41 8.8 28.4 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 RLN86633.1 - 3.3 6.0 24.5 3.9 5.8 24.5 1.1 1 0 0 1 1 1 0 Mpp10 protein CobT PF06213.12 RLN86633.1 - 6.2 6.1 30.0 8.4 5.7 30.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2428 PF10350.9 RLN86633.1 - 7.6 5.7 5.3 12 5.1 5.3 1.3 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) CDC45 PF02724.14 RLN86633.1 - 8.8 4.5 25.4 11 4.2 25.4 1.1 1 0 0 1 1 1 0 CDC45-like protein 7tm_3 PF00003.22 RLN86634.1 - 8.1e-38 130.5 28.3 1.2e-37 129.9 28.3 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR TPH PF13868.6 RLN86636.1 - 9.2e-19 67.2 74.4 1e-18 67.0 74.4 1.0 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain WD40 PF00400.32 RLN86637.1 - 1.5e-34 117.4 9.2 1.1e-08 35.6 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Prp19 PF08606.11 RLN86637.1 - 3.6e-30 103.7 1.7 5.6e-30 103.1 0.8 1.9 2 0 0 2 2 2 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 RLN86637.1 - 2.9e-11 43.5 0.1 0.0033 17.7 0.0 5.8 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain zf-Nse PF11789.8 RLN86637.1 - 1.4e-06 28.0 0.1 2.3e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit eIF2A PF08662.11 RLN86637.1 - 0.00039 20.3 0.0 3.1 7.6 0.0 3.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 RLN86637.1 - 0.00095 18.2 0.5 0.17 10.8 0.0 3.4 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-NOSIP PF15906.5 RLN86637.1 - 0.094 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 RLN86637.1 - 0.1 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 U-box domain WD40_like PF17005.5 RLN86637.1 - 0.25 10.6 0.0 0.87 8.8 0.0 1.7 2 1 0 2 2 2 0 WD40-like domain Dickkopf_N PF04706.12 RLN86638.1 - 7.3 7.2 8.2 1.8 9.1 0.5 2.4 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region DUF4084 PF13321.6 RLN86639.1 - 0.0048 16.5 0.7 0.009 15.6 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4084) DUF4956 PF16316.5 RLN86639.1 - 0.056 13.1 4.3 1 9.0 0.7 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4956) ADH_zinc_N_2 PF13602.6 RLN86641.1 - 8.6e-12 46.3 0.0 9e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MGS PF02142.22 RLN86641.1 - 0.053 13.7 0.0 0.056 13.6 0.0 1.1 1 0 0 1 1 1 0 MGS-like domain PVL_ORF50 PF07768.11 RLN86642.1 - 0.018 15.3 0.9 0.027 14.8 0.9 1.2 1 0 0 1 1 1 0 PVL ORF-50-like family LmjF365940-deam PF14421.6 RLN86645.1 - 1.3e-64 217.4 2.3 4e-64 215.8 2.3 1.7 1 1 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases dCMP_cyt_deam_1 PF00383.23 RLN86645.1 - 0.1 12.5 0.0 5 7.1 0.0 2.3 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region Ion_trans PF00520.31 RLN86646.1 - 7.5e-23 81.0 21.8 2e-20 73.1 15.4 2.2 2 0 0 2 2 2 2 Ion transport protein MPS2 PF17060.5 RLN86646.1 - 0.018 14.3 3.5 0.034 13.4 3.5 1.4 1 0 0 1 1 1 0 Monopolar spindle protein 2 zf-RING_2 PF13639.6 RLN86647.1 - 8e-09 35.7 9.2 1.9e-08 34.5 9.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RLN86647.1 - 1.8e-07 30.9 6.0 3.5e-07 30.0 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN86647.1 - 3.5e-07 30.4 5.7 8.9e-07 29.1 5.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RLN86647.1 - 4.2e-07 29.7 8.3 1.1e-06 28.4 8.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN86647.1 - 3.7e-06 26.7 9.4 7.4e-06 25.7 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN86647.1 - 2e-05 24.5 2.7 0.00012 22.0 1.3 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 RLN86647.1 - 2.5e-05 24.3 3.6 5.9e-05 23.0 3.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 RLN86647.1 - 5.1e-05 23.0 7.2 0.00011 21.9 7.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN86647.1 - 0.0064 16.4 10.7 0.049 13.6 11.0 2.2 1 1 1 2 2 2 1 zinc-RING finger domain PX PF00787.24 RLN86647.1 - 0.064 13.2 0.2 0.15 12.0 0.2 1.5 1 0 0 1 1 1 0 PX domain zf-RING_4 PF14570.6 RLN86647.1 - 0.32 10.8 11.1 0.32 10.8 7.3 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 RLN86647.1 - 0.5 10.5 5.4 4.6 7.5 3.9 2.5 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 RLN86647.1 - 0.51 10.1 5.0 1.6 8.5 1.8 2.7 2 1 0 2 2 2 0 RING-like zinc finger Rad50_zn_hook PF04423.14 RLN86647.1 - 0.57 10.1 5.1 3.6 7.5 0.6 2.8 2 1 1 3 3 3 0 Rad50 zinc hook motif Zn_ribbon_17 PF17120.5 RLN86647.1 - 1.1 8.9 10.6 0.15 11.7 6.2 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 RLN86647.1 - 7.4 6.8 10.7 9.7 6.4 8.5 2.3 2 0 0 2 2 2 0 RING-variant domain RCC1 PF00415.18 RLN86648.1 - 3.2e-39 133.3 17.1 3.5e-09 37.1 0.1 7.6 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN86648.1 - 2.5e-24 84.5 27.7 1.5e-08 34.2 0.4 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat TIG PF01833.24 RLN86648.1 - 6.9e-09 35.7 0.1 0.01 15.9 0.0 5.0 4 2 0 4 4 4 2 IPT/TIG domain Astacin PF01400.24 RLN86649.1 - 1.8e-24 86.4 0.0 2.8e-23 82.5 0.0 2.1 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 RLN86649.1 - 0.007 16.9 0.6 0.019 15.5 0.1 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 RLN86649.1 - 0.16 11.8 0.9 0.38 10.6 0.9 1.6 1 0 0 1 1 1 0 Matrixin WD40 PF00400.32 RLN86650.1 - 4.7e-11 43.1 5.2 0.0048 17.7 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN86650.1 - 0.00056 20.2 0.1 9.5 6.6 0.0 4.3 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RLN86650.1 - 0.011 15.6 0.0 0.38 10.6 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 RLN86650.1 - 0.22 10.8 0.0 1 8.6 0.0 1.9 2 0 0 2 2 2 0 WD40-like domain DUF3689 PF12463.8 RLN86651.1 - 1.2e-109 366.4 0.4 2.3e-109 365.5 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3689) Pkinase_Tyr PF07714.17 RLN86653.1 - 1.2e-58 198.4 0.0 1.1e-42 146.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN86653.1 - 4.4e-49 167.2 0.0 2.3e-36 125.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Arm PF00514.23 RLN86653.1 - 3.4e-25 87.2 4.7 8e-05 22.5 0.0 9.6 10 0 0 10 10 10 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN86653.1 - 1.2e-07 32.0 18.4 0.011 16.1 0.8 4.9 5 1 1 6 6 5 4 HEAT repeats HEAT PF02985.22 RLN86653.1 - 1.6e-06 27.9 8.0 16 6.1 0.0 8.1 8 0 0 8 8 8 1 HEAT repeat HEAT_EZ PF13513.6 RLN86653.1 - 3.5e-06 27.4 12.4 1.3 9.6 0.2 6.4 5 1 0 5 5 5 3 HEAT-like repeat Kinase-like PF14531.6 RLN86653.1 - 0.0079 15.5 0.0 0.45 9.8 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 RLN86653.1 - 0.059 12.7 0.0 4.7 6.5 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN86653.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase MoaE PF02391.17 RLN86653.1 - 0.15 12.4 0.0 22 5.3 0.0 3.2 3 0 0 3 3 3 0 MoaE protein CRA_rpt PF07046.11 RLN86653.1 - 0.46 10.7 2.2 1.4e+02 2.8 0.0 3.7 3 0 0 3 3 3 0 Cytoplasmic repetitive antigen (CRA) like repeat DUF2508 PF10704.9 RLN86654.1 - 0.025 14.7 2.4 0.025 14.7 2.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) DUF2937 PF11157.8 RLN86654.1 - 0.052 13.3 0.5 0.095 12.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Presenilin PF01080.17 RLN86654.1 - 2.8 6.6 7.5 3.9 6.1 7.5 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 RLN86654.1 - 7.1 4.8 10.6 10 4.3 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.10 RLN86654.1 - 7.5 5.1 9.9 10 4.6 9.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ribosomal_60s PF00428.19 RLN86656.1 - 4.1 8.0 9.4 4.5 7.9 3.3 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein CAF-1_p150 PF11600.8 RLN86657.1 - 0.064 13.0 20.7 0.081 12.6 20.7 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Afi1 PF07792.12 RLN86657.1 - 0.09 13.3 1.7 0.1 13.1 1.7 1.0 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Pinin_SDK_memA PF04696.13 RLN86657.1 - 0.13 12.3 15.0 0.15 12.1 15.0 1.1 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF4207 PF13904.6 RLN86657.1 - 0.3 10.8 12.0 0.3 10.7 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) DEAD PF00270.29 RLN86660.1 - 9.1e-41 139.5 0.0 1.2e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN86660.1 - 6.6e-17 61.9 0.1 5.2e-16 59.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN86660.1 - 1.6e-05 25.0 0.0 2.7e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RLN86660.1 - 0.0025 18.2 0.1 0.0053 17.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RLN86660.1 - 0.0035 17.1 0.0 0.0055 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RLN86660.1 - 0.0054 17.0 0.1 0.014 15.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 RLN86660.1 - 0.054 12.9 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein DUF2075 PF09848.9 RLN86660.1 - 0.059 12.6 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 RLN86660.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 1 0 1 1 1 0 Helicase DUF2508 PF10704.9 RLN86661.1 - 0.078 13.2 20.3 0.7 10.1 3.4 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) MAT1-1-2 PF17043.5 RLN86661.1 - 0.1 12.5 0.1 0.26 11.1 0.1 1.7 1 0 0 1 1 1 0 Mating type protein 1-1-2 of unknown function DUF2353 PF09789.9 RLN86661.1 - 3.8 6.8 25.6 0.0082 15.5 5.7 3.3 3 0 0 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) SAS4 PF15460.6 RLN86662.1 - 0.15 12.2 6.8 0.085 13.0 3.6 2.1 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 Ax_dynein_light PF10211.9 RLN86663.1 - 0.013 15.5 1.5 0.025 14.5 1.5 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain Birna_VP3 PF01767.16 RLN86663.1 - 0.028 14.5 0.3 0.049 13.7 0.3 1.4 1 0 0 1 1 1 0 Birnavirus VP3 protein Val_tRNA-synt_C PF10458.9 RLN86663.1 - 0.033 14.5 1.7 0.057 13.7 1.7 1.4 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm HAUS-augmin3 PF14932.6 RLN86663.1 - 0.046 13.3 3.1 0.077 12.6 3.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ZapB PF06005.12 RLN86663.1 - 0.071 13.6 5.1 0.18 12.3 5.1 1.7 1 0 0 1 1 1 0 Cell division protein ZapB Clp1 PF06807.14 RLN86663.1 - 0.071 13.5 1.0 13 6.3 0.4 2.5 2 0 0 2 2 2 0 Pre-mRNA cleavage complex II protein Clp1 TAF4 PF05236.14 RLN86663.1 - 0.093 12.5 2.9 0.18 11.5 2.9 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family End3 PF12761.7 RLN86663.1 - 0.16 12.1 2.8 0.29 11.3 2.8 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Spc24 PF08286.11 RLN86663.1 - 0.24 11.7 4.9 0.2 11.9 3.0 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 IFP_35_N PF07334.13 RLN86663.1 - 0.3 11.2 1.1 0.56 10.3 1.1 1.4 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus APG6_N PF17675.1 RLN86663.1 - 0.42 11.1 9.5 0.99 9.9 9.5 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region TSC22 PF01166.18 RLN86663.1 - 0.46 10.8 3.3 1.4 9.3 3.3 1.9 1 1 0 1 1 1 0 TSC-22/dip/bun family UPF0242 PF06785.11 RLN86663.1 - 0.65 10.1 5.8 1.4 9.0 5.8 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 RLN86663.1 - 0.78 9.5 5.2 1.4 8.7 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4055 PF13264.6 RLN86663.1 - 1 9.5 6.0 1.7 8.8 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) Vir_act_alpha_C PF10400.9 RLN86663.1 - 1.5 9.5 6.1 0.7 10.6 3.4 1.9 2 0 0 2 2 2 0 Virulence activator alpha C-term NAD_binding_1 PF00175.21 RLN86664.1 - 0.0021 18.7 0.2 0.0052 17.4 0.2 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Ala_racemase_N PF01168.20 RLN86665.1 - 6.9e-25 88.0 3.9 1.1e-24 87.3 3.9 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 RLN86665.1 - 3.5e-21 75.7 0.1 1.8e-20 73.4 0.0 2.1 2 0 0 2 2 2 1 Putative serine dehydratase domain BBL5 PF07289.11 RLN86666.1 - 7.6e-150 498.5 0.0 8.6e-150 498.4 0.0 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein PH_TFIIH PF08567.11 RLN86666.1 - 1.2e-05 25.6 0.0 0.043 14.1 0.0 2.4 2 0 0 2 2 2 2 TFIIH p62 subunit, N-terminal domain Voldacs PF03517.13 RLN86666.1 - 7.7e-05 22.8 0.0 0.29 11.3 0.0 2.5 2 0 0 2 2 2 2 Regulator of volume decrease after cellular swelling bPH_3 PF14470.6 RLN86666.1 - 0.00047 20.5 0.0 0.0072 16.7 0.0 2.3 2 0 0 2 2 2 1 Bacterial PH domain Vps36_ESCRT-II PF11605.8 RLN86666.1 - 0.00058 20.0 0.1 0.33 11.2 0.1 2.3 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 ADIP PF11559.8 RLN86668.1 - 0.23 11.5 2.1 0.44 10.6 2.1 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Uds1 PF15456.6 RLN86669.1 - 0.7 10.1 5.3 0.21 11.8 1.5 2.0 3 0 0 3 3 3 0 Up-regulated During Septation Pecanex_C PF05041.15 RLN86670.1 - 0.17 11.4 0.8 0.31 10.6 0.8 1.3 1 0 0 1 1 1 0 Pecanex protein (C-terminus) QLQ PF08880.11 RLN86672.1 - 0.17 11.7 0.3 0.42 10.4 0.2 1.7 2 0 0 2 2 2 0 QLQ CALM_bind PF16025.5 RLN86673.1 - 0.39 11.2 5.6 0.29 11.6 0.7 2.3 2 0 0 2 2 2 0 Calcium-dependent calmodulin binding MAD PF05557.13 RLN86674.1 - 0.019 13.4 3.3 0.035 12.5 3.3 1.4 1 0 0 1 1 1 0 Mitotic checkpoint protein Occludin_ELL PF07303.13 RLN86674.1 - 0.072 13.8 0.3 0.23 12.2 0.3 1.9 1 0 0 1 1 1 0 Occludin homology domain TSC22 PF01166.18 RLN86674.1 - 0.49 10.7 3.8 0.69 10.3 0.2 2.7 2 1 1 3 3 3 0 TSC-22/dip/bun family bZIP_2 PF07716.15 RLN86674.1 - 3 8.0 14.7 0.85 9.8 3.3 3.2 3 0 0 3 3 3 0 Basic region leucine zipper Tropomyosin_1 PF12718.7 RLN86674.1 - 7.4 6.7 10.8 3.9 7.6 6.7 2.4 2 1 1 3 3 3 0 Tropomyosin like DUF2205 PF10224.9 RLN86675.1 - 0.036 14.1 0.5 0.089 12.8 0.5 1.6 1 0 0 1 1 1 0 Short coiled-coil protein bPH_1 PF08000.11 RLN86676.1 - 0.055 13.6 0.0 4 7.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial PH domain CUE PF02845.16 RLN86678.1 - 0.00028 20.5 0.0 0.00051 19.7 0.0 1.4 1 0 0 1 1 1 1 CUE domain SinI PF08671.10 RLN86678.1 - 0.033 14.0 0.1 0.071 12.9 0.1 1.6 1 0 0 1 1 1 0 Anti-repressor SinI EF-hand_5 PF13202.6 RLN86678.1 - 0.12 11.9 0.0 11 5.8 0.0 2.6 2 0 0 2 2 2 0 EF hand LRR_8 PF13855.6 RLN86679.1 - 3.9e-06 26.5 0.6 0.025 14.3 0.0 3.6 2 1 3 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 RLN86679.1 - 0.014 15.8 1.9 6.8 7.3 0.0 3.5 2 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Rhodanese PF00581.20 RLN86680.1 - 2.5e-05 24.7 0.0 6.8e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Rhodanese-like domain BSD PF03909.17 RLN86681.1 - 4.4e-08 33.0 0.0 1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 BSD domain CHS5_N PF16892.5 RLN86682.1 - 0.0025 17.7 0.0 0.0092 15.9 0.0 1.8 2 0 0 2 2 2 1 Chitin biosynthesis protein CHS5 N-terminus Acyl_transf_3 PF01757.22 RLN86682.1 - 0.0039 16.3 2.4 0.0053 15.9 2.3 1.4 1 1 0 1 1 1 1 Acyltransferase family AhpC-TSA PF00578.21 RLN86683.1 - 3.6e-38 130.3 0.0 4.6e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RLN86683.1 - 4.4e-17 62.2 0.0 6.4e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 RLN86683.1 - 6.4e-12 45.1 0.0 1.3e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 RLN86683.1 - 0.01 15.8 0.2 0.032 14.1 0.2 1.7 2 0 0 2 2 2 1 SCO1/SenC Aa_trans PF01490.18 RLN86685.1 - 7.8e-39 133.5 14.3 1.3e-38 132.8 14.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Flp1_like PF16982.5 RLN86685.1 - 0.51 9.8 4.7 1.4 8.4 4.7 1.7 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain DUF5383 PF17355.2 RLN86685.1 - 0.7 10.3 0.1 0.7 10.3 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5383) ATPase_gene1 PF09527.10 RLN86685.1 - 2.8 8.2 8.6 2.3 8.4 3.6 3.2 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter RRN3 PF05327.11 RLN86688.1 - 0.065 11.8 0.5 0.13 10.8 0.4 1.5 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 ER PF01133.17 RLN86688.1 - 0.16 12.0 0.0 0.44 10.6 0.0 1.7 1 0 0 1 1 1 0 Enhancer of rudimentary RR_TM4-6 PF06459.12 RLN86688.1 - 3.1 7.6 6.7 0.74 9.6 2.7 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Sporozoite_P67 PF05642.11 RLN86688.1 - 8.7 4.3 6.6 13 3.7 6.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LRR_4 PF12799.7 RLN86689.1 - 5.7e-17 61.6 13.5 8e-08 32.5 0.6 3.7 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN86689.1 - 3.7e-12 46.1 0.7 9e-07 28.6 0.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 RLN86689.1 - 5.3e-09 35.7 8.4 8.7e-05 22.2 0.7 3.5 1 1 3 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 RLN86689.1 - 0.016 15.7 8.9 26 5.9 0.1 4.8 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 RLN86689.1 - 0.054 13.6 5.9 20 5.6 0.0 4.4 3 1 1 4 4 4 0 Leucine Rich repeat CBFD_NFYB_HMF PF00808.23 RLN86690.1 - 3.3e-22 78.5 0.1 9e-22 77.1 0.1 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 RLN86690.1 - 3.3e-15 56.6 0.5 3.3e-15 56.6 0.5 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Ank_3 PF13606.6 RLN86690.1 - 1.7e-07 30.9 0.3 0.019 15.5 0.1 4.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 RLN86690.1 - 5.4e-07 30.1 0.1 2.9e-06 27.8 0.1 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN86690.1 - 1.7e-06 28.2 0.3 0.0014 18.9 0.2 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN86690.1 - 0.00016 22.0 2.4 0.0021 18.4 0.5 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 RLN86690.1 - 0.0017 18.9 0.6 0.45 11.1 0.1 3.2 1 1 2 3 3 3 1 Ankyrin repeats (many copies) TAF PF02969.17 RLN86690.1 - 0.06 13.5 0.1 0.18 12.0 0.1 1.8 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) NAD_binding_2 PF03446.15 RLN86691.1 - 1e-48 165.5 0.6 1.5e-48 165.0 0.6 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 RLN86691.1 - 2.7e-20 72.8 0.1 1.6e-19 70.3 0.1 2.1 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 RLN86691.1 - 4.4e-07 30.4 0.1 9.1e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 RLN86691.1 - 8.1e-07 28.6 0.0 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 RLN86691.1 - 1.5e-05 24.6 0.1 2.5e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 RLN86691.1 - 0.00013 21.9 0.3 0.00055 19.9 0.4 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PDH PF02153.17 RLN86691.1 - 0.0027 16.7 0.1 0.0035 16.4 0.1 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase TrkA_N PF02254.18 RLN86691.1 - 0.0054 17.0 0.2 0.013 15.7 0.2 1.7 1 1 0 1 1 1 1 TrkA-N domain Rossmann-like PF10727.9 RLN86691.1 - 0.0086 15.9 0.4 0.018 14.9 0.4 1.5 1 0 0 1 1 1 1 Rossmann-like domain UDPG_MGDP_dh_C PF03720.15 RLN86691.1 - 0.021 15.3 0.2 0.043 14.2 0.2 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Shikimate_DH PF01488.20 RLN86691.1 - 0.021 14.9 0.4 0.064 13.3 0.3 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 RLN86691.1 - 0.031 13.8 0.3 2.6 7.6 0.2 2.2 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 RLN86691.1 - 0.047 13.9 0.2 0.12 12.7 0.2 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain HSP70 PF00012.20 RLN86692.1 - 2.5e-152 508.2 1.2 2.8e-152 508.0 1.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN86692.1 - 9.6e-16 57.5 0.8 8.8e-14 51.0 0.4 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.18 RLN86692.1 - 2e-05 24.0 0.3 0.18 11.1 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase HOIP-UBA PF16678.5 RLN86692.1 - 0.081 12.9 0.2 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 HOIP UBA domain pair FtsA PF14450.6 RLN86692.1 - 0.084 13.3 0.1 8.3 6.9 0.0 2.7 2 1 0 2 2 2 0 Cell division protein FtsA NAD_binding_2 PF03446.15 RLN86693.1 - 4.2e-49 166.8 0.7 6.3e-49 166.2 0.7 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 RLN86693.1 - 1.2e-28 99.8 0.0 2.2e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 RLN86693.1 - 3.1e-07 30.9 0.2 1e-06 29.2 0.1 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 RLN86693.1 - 3.2e-07 29.9 0.1 8.1e-07 28.6 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 RLN86693.1 - 1.3e-05 24.9 0.1 2.1e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 RLN86693.1 - 8.7e-05 22.5 0.6 0.00054 19.9 0.5 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PDH PF02153.17 RLN86693.1 - 0.002 17.2 0.2 0.0026 16.8 0.2 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase TrkA_N PF02254.18 RLN86693.1 - 0.0035 17.6 0.2 0.0084 16.4 0.2 1.7 1 1 0 1 1 1 1 TrkA-N domain Rossmann-like PF10727.9 RLN86693.1 - 0.012 15.5 0.8 0.026 14.4 0.8 1.5 1 0 0 1 1 1 0 Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 RLN86693.1 - 0.022 14.3 0.3 1.9 8.0 0.2 2.2 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 RLN86693.1 - 0.023 14.7 0.5 0.069 13.2 0.4 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_C PF03720.15 RLN86693.1 - 0.026 14.9 0.2 0.057 13.8 0.2 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Sacchrp_dh_NADP PF03435.18 RLN86693.1 - 0.036 14.3 0.5 0.1 12.9 0.2 2.0 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Galactosyl_T PF01762.21 RLN86695.1 - 1.6e-22 80.3 0.0 2.5e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase UCH PF00443.29 RLN86696.1 - 1.2e-31 110.2 0.0 1.9e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Galactosyl_T PF01762.21 RLN86696.1 - 3.1e-24 85.9 0.0 5.2e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Glyco_transf_10 PF00852.19 RLN86696.1 - 1.4e-17 64.0 0.0 2.8e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term UCH_1 PF13423.6 RLN86696.1 - 1.4e-05 24.8 0.0 2.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Galactosyl_T PF01762.21 RLN86697.1 - 2e-26 93.0 0.0 3.3e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase HTH_Tnp_Tc5 PF03221.16 RLN86698.1 - 4.8e-05 23.3 0.0 7.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF4570 PF15134.6 RLN86699.1 - 0.036 14.1 0.2 0.06 13.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) Anticodon_1 PF08264.13 RLN86700.1 - 5.4e-11 42.7 0.0 1.1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.22 RLN86700.1 - 4.5e-10 38.4 0.0 6.4e-10 37.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 RLN86700.1 - 8.6e-09 34.6 0.0 1.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 RLN86700.1 - 1.4e-08 34.5 0.0 3.2e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 RLN86700.1 - 0.098 11.6 0.0 1.9 7.3 0.0 2.1 1 1 1 2 2 2 0 tRNA synthetases class I (K) DUF4486 PF14858.6 RLN86701.1 - 4.6e-07 28.7 1.4 5e-07 28.6 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4486) TPR_8 PF13181.6 RLN86701.1 - 0.015 15.5 0.1 13 6.3 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat fn3 PF00041.21 RLN86701.1 - 0.1 13.0 0.0 0.37 11.2 0.0 2.0 1 0 0 1 1 1 0 Fibronectin type III domain TPR_12 PF13424.6 RLN86701.1 - 2.8 8.3 7.4 23 5.4 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN86701.1 - 7 7.0 8.7 1.1 9.6 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat GCP_N_terminal PF17681.1 RLN86702.1 - 4.5e-22 79.1 0.0 1.1e-13 51.6 0.0 2.5 1 1 2 3 3 3 2 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 RLN86702.1 - 1e-16 61.3 0.0 2.1e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal WD40 PF00400.32 RLN86703.1 - 1.7e-17 63.4 14.8 7.1e-06 26.7 0.1 10.2 11 0 0 11 11 11 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN86703.1 - 1.8e-07 31.4 0.0 0.36 11.1 0.0 6.5 6 1 1 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain CENP-F_leu_zip PF10473.9 RLN86703.1 - 0.00054 20.0 12.1 0.00054 20.0 12.1 6.6 2 2 3 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KASH_CCD PF14662.6 RLN86703.1 - 0.0012 18.7 21.7 0.0012 18.7 21.7 4.9 2 1 2 4 4 4 2 Coiled-coil region of CCDC155 or KASH Laminin_II PF06009.12 RLN86703.1 - 0.55 10.3 16.4 0.022 14.8 6.6 3.3 2 1 0 2 2 2 0 Laminin Domain II eIF2_C PF09173.11 RLN86704.1 - 6.1e-37 125.7 0.8 1.7e-36 124.3 0.8 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 RLN86704.1 - 2.8e-23 82.5 1.4 1.5e-22 80.1 1.4 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 RLN86704.1 - 5.3e-14 52.4 0.8 5.4e-13 49.1 0.8 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RLN86704.1 - 0.0024 18.0 0.0 0.007 16.4 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RLN86704.1 - 0.014 15.3 1.0 0.25 11.2 0.2 2.4 2 0 0 2 2 2 0 RsgA GTPase DUF1098 PF06497.11 RLN86704.1 - 0.09 13.3 0.4 0.35 11.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) DUF1677 PF07911.13 RLN86705.1 - 0.0047 17.3 1.6 0.0047 17.3 1.6 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1677) AP3D1 PF06375.11 RLN86705.1 - 0.0064 16.7 11.0 0.0077 16.5 11.0 1.1 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 Mucin PF01456.17 RLN86705.1 - 0.078 13.0 3.7 0.1 12.6 3.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Hydin_ADK PF17213.3 RLN86705.1 - 0.51 10.6 6.3 0.54 10.5 6.3 1.0 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Presenilin PF01080.17 RLN86705.1 - 3 6.5 3.6 3.1 6.4 3.6 1.2 1 0 0 1 1 1 0 Presenilin RRM_1 PF00076.22 RLN86706.1 - 1.4e-32 111.3 0.2 4.6e-16 58.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 RLN86706.1 - 1.1e-29 101.7 39.6 2.2e-06 27.4 1.5 5.7 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RLN86706.1 - 2.6e-25 87.7 64.7 2.3e-06 27.4 5.8 5.5 5 0 0 5 5 5 5 Zinc finger domain zf-CCCH_4 PF18044.1 RLN86706.1 - 6.1e-22 77.0 43.5 6.5e-06 25.8 1.9 5.7 5 0 0 5 5 5 5 CCCH-type zinc finger Torus PF16131.5 RLN86706.1 - 8.1e-14 52.2 43.4 0.00012 22.7 0.4 6.7 4 2 3 7 7 6 5 Torus domain zf-CCCH_3 PF15663.5 RLN86706.1 - 1.8e-07 31.3 18.4 0.22 11.8 0.1 5.5 4 1 0 4 4 4 3 Zinc-finger containing family RRM_7 PF16367.5 RLN86706.1 - 2.1e-07 31.0 0.1 0.0012 18.9 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif RNA_polI_A34 PF08208.11 RLN86706.1 - 0.00067 19.8 28.0 0.00067 19.8 28.0 1.8 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 RRM_8 PF11835.8 RLN86706.1 - 0.042 14.1 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 RRM-like domain zf-CCCH_2 PF14608.6 RLN86706.1 - 0.045 14.2 50.2 0.044 14.3 4.1 5.6 5 0 0 5 5 5 0 RNA-binding, Nab2-type zinc finger Chi-conotoxin PF16981.5 RLN86706.1 - 0.06 13.6 0.9 2.1 8.6 0.1 2.8 2 0 0 2 2 2 0 chi-Conotoxin or t superfamily AAA_11 PF13086.6 RLN86706.1 - 2.1 8.1 10.2 3.1 7.5 10.2 1.3 1 0 0 1 1 1 0 AAA domain SAPS PF04499.15 RLN86706.1 - 5.2 5.7 9.0 7.7 5.2 9.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4820 PF16091.5 RLN86706.1 - 6.4 6.1 10.3 17 4.7 10.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) VIR_N PF15912.5 RLN86706.1 - 7.2 6.1 12.5 15 5.1 12.5 1.6 1 0 0 1 1 1 0 Virilizer, N-terminal Sld5 PF05916.11 RLN86707.1 - 3.9e-17 62.7 0.2 7.6e-17 61.7 0.2 1.5 1 1 0 1 1 1 1 GINS complex protein TIMELESS PF04821.14 RLN86707.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Timeless protein Pkinase PF00069.25 RLN86708.1 - 4e-63 213.3 0.0 4.7e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN86708.1 - 5.6e-35 120.9 0.0 6.8e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN86708.1 - 1.6e-10 40.8 0.0 2.7e-10 40.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN86708.1 - 1.7e-07 30.8 0.0 2.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RLN86708.1 - 3e-05 23.7 0.0 4.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 RLN86708.1 - 0.011 15.6 6.7 0.11 12.3 0.1 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 RLN86708.1 - 0.05 13.1 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Peptidase_C13 PF01650.18 RLN86709.1 - 3e-97 325.2 0.0 5.3e-97 324.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase C13 family TUDOR PF00567.24 RLN86709.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Tudor domain RelB PF04221.12 RLN86709.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 RelB antitoxin cNMP_binding PF00027.29 RLN86710.1 - 2.3e-09 37.2 0.0 4.3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 RLN86710.1 - 3.4e-09 36.4 0.0 6.1e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain DUF601 PF04642.12 RLN86710.1 - 0.16 11.5 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 PDZ_6 PF17820.1 RLN86711.1 - 1.2e-05 25.1 0.3 0.00013 21.8 0.1 2.5 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 RLN86711.1 - 0.0018 18.6 0.0 0.0064 16.8 0.0 2.0 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RLN86711.1 - 0.1 13.0 0.1 0.35 11.2 0.0 2.0 1 1 0 1 1 1 0 PDZ domain ADIP PF11559.8 RLN86711.1 - 0.13 12.4 4.2 0.21 11.7 4.2 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding RVT_N PF13655.6 RLN86711.1 - 0.27 11.5 2.3 0.61 10.4 2.3 1.5 1 0 0 1 1 1 0 N-terminal domain of reverse transcriptase DUF4407 PF14362.6 RLN86711.1 - 0.7 9.2 9.5 0.92 8.8 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ank_4 PF13637.6 RLN86712.1 - 5.5e-12 46.0 0.0 0.00012 22.5 0.0 3.1 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN86712.1 - 6.9e-11 42.2 0.4 0.00056 20.2 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN86712.1 - 3e-09 36.9 0.2 2e-05 24.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 RLN86712.1 - 4.6e-07 30.3 0.0 0.0032 18.0 0.1 2.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN86712.1 - 0.0027 18.0 0.0 11 7.0 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Pkinase PF00069.25 RLN86713.1 - 0.0033 16.8 0.0 0.0053 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 RLN86713.1 - 0.035 13.5 0.0 0.088 12.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2721 PF11026.8 RLN86714.1 - 0.25 11.2 1.4 0.39 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Iwr1 PF08574.10 RLN86714.1 - 1.8 9.6 9.0 0.21 12.6 0.5 2.8 2 1 0 2 2 2 0 Transcription factor Iwr1 Y_phosphatase2 PF03162.13 RLN86716.1 - 1.1e-13 51.1 0.0 3.3e-13 49.6 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family LRR_6 PF13516.6 RLN86717.1 - 1.7e-41 136.8 20.8 0.0017 18.3 0.0 15.7 15 0 0 15 15 15 10 Leucine Rich repeat LRR_4 PF12799.7 RLN86717.1 - 6.6e-15 55.0 12.2 0.21 12.1 0.0 10.4 9 4 4 13 13 13 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN86717.1 - 9.7e-10 37.6 2.6 14 6.7 0.0 10.4 14 0 0 14 14 14 1 Leucine Rich Repeat LRR_8 PF13855.6 RLN86717.1 - 1.3e-08 34.5 14.6 0.5 10.2 0.1 10.3 8 4 1 9 9 9 3 Leucine rich repeat LRR_2 PF07723.13 RLN86717.1 - 0.0059 17.2 1.3 27 5.6 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat Drc1-Sld2 PF11719.8 RLN86717.1 - 0.21 11.1 1.2 0.3 10.6 1.2 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF4632 PF15451.6 RLN86717.1 - 0.42 10.7 1.5 1.3 9.2 1.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) RRN3 PF05327.11 RLN86717.1 - 2.2 6.7 4.2 3.3 6.1 4.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 RLN86717.1 - 6 6.1 8.5 12 5.1 8.5 1.4 1 0 0 1 1 1 0 NOA36 protein SBP_bac_6 PF13343.6 RLN86718.1 - 7e-15 55.1 0.1 8.2e-12 45.0 0.1 2.2 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 RLN86718.1 - 2.7e-10 40.5 5.8 4.5e-10 39.8 5.8 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 RLN86718.1 - 6.1e-08 33.0 6.4 2e-07 31.3 6.4 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 RLN86718.1 - 0.0027 17.5 0.2 0.0083 15.9 0.2 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SNAP PF14938.6 RLN86719.1 - 1e-85 287.6 25.1 1.9e-85 286.7 25.1 1.4 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 RLN86719.1 - 0.00046 20.1 1.1 0.00046 20.1 1.1 5.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 RLN86719.1 - 0.0006 19.3 3.5 0.00088 18.7 3.5 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_1 PF00515.28 RLN86719.1 - 0.0013 18.5 2.8 0.0013 18.5 2.8 5.1 6 1 1 7 7 7 1 Tetratricopeptide repeat DUF4145 PF13643.6 RLN86719.1 - 0.0027 17.8 0.1 0.0064 16.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4145) TPR_14 PF13428.6 RLN86719.1 - 0.0029 18.3 4.7 0.69 10.9 0.3 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN86719.1 - 0.0037 17.4 12.1 0.0075 16.4 1.5 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN86719.1 - 0.0067 16.7 9.2 0.025 14.9 0.5 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN86719.1 - 0.007 16.3 6.4 0.18 11.9 1.1 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN86719.1 - 0.022 15.4 8.1 0.028 15.1 2.1 3.1 2 1 1 3 3 2 0 Tetratricopeptide repeat RPN7 PF10602.9 RLN86719.1 - 0.041 13.6 5.3 0.042 13.6 1.8 2.4 1 1 0 2 2 2 0 26S proteasome subunit RPN7 PPR_1 PF12854.7 RLN86719.1 - 0.05 13.3 0.1 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 PPR repeat NicO PF03824.16 RLN86719.1 - 0.09 12.1 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 High-affinity nickel-transport protein TPR_6 PF13174.6 RLN86719.1 - 0.15 12.7 0.5 0.15 12.7 0.5 4.4 4 1 1 5 5 4 0 Tetratricopeptide repeat MIT PF04212.18 RLN86719.1 - 0.25 11.4 17.2 1.4 9.0 7.9 4.1 2 1 3 5 5 4 0 MIT (microtubule interacting and transport) domain ANAPC5 PF12862.7 RLN86719.1 - 1 9.5 5.1 0.86 9.7 2.0 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 DUF3958 PF13125.6 RLN86719.1 - 5.2 7.3 7.7 8.2 6.7 0.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3958) SBP_bac_6 PF13343.6 RLN86720.1 - 6.7e-16 58.4 0.6 1.1e-13 51.2 0.3 2.2 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 RLN86720.1 - 4.1e-13 49.8 4.0 4.1e-13 49.8 4.0 1.5 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 RLN86720.1 - 1.2e-09 38.6 5.5 2.2e-09 37.7 5.5 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 RLN86720.1 - 0.00022 21.1 0.0 0.00053 19.8 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Tymo_coat PF00983.18 RLN86721.1 - 0.028 14.2 0.3 0.043 13.7 0.3 1.3 1 0 0 1 1 1 0 Tymovirus coat protein AROS PF15684.5 RLN86722.1 - 0.0037 17.8 5.8 0.0051 17.4 5.8 1.2 1 0 0 1 1 1 1 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 DUF1180 PF06679.12 RLN86722.1 - 0.04 14.3 1.9 0.057 13.8 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) BEX PF04538.12 RLN86722.1 - 0.1 13.2 3.9 0.16 12.6 3.9 1.4 1 0 0 1 1 1 0 Brain expressed X-linked like family SNARE PF05739.19 RLN86722.1 - 3.2 7.8 4.4 1.2 9.2 0.1 2.1 2 0 0 2 2 2 0 SNARE domain Ribosomal_S3Ae PF01015.18 RLN86723.1 - 3.9e-91 304.1 3.3 4.7e-91 303.9 3.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 RLN86723.1 - 0.19 11.3 0.0 0.43 10.2 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region FYVE PF01363.21 RLN86724.1 - 4.3e-13 49.2 4.6 8.2e-13 48.3 4.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN86724.1 - 0.011 15.9 4.6 0.013 15.7 1.5 2.4 3 0 0 3 3 3 0 FYVE-type zinc finger DUF1677 PF07911.13 RLN86724.1 - 0.071 13.5 0.2 0.33 11.4 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1677) GIDA PF01134.22 RLN86725.1 - 1.3e-148 495.2 0.0 2e-148 494.7 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 RLN86725.1 - 8.7e-60 202.5 0.2 1.2e-59 202.0 0.2 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 RLN86725.1 - 1.4e-07 31.2 2.1 1.4e-07 31.2 2.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RLN86725.1 - 1.1e-06 28.1 3.3 6.1e-06 25.7 3.4 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 RLN86725.1 - 9.3e-06 25.0 7.5 3.1e-05 23.2 5.0 2.4 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 RLN86725.1 - 0.00017 21.3 1.6 0.2 11.2 1.3 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 RLN86725.1 - 0.00065 20.2 0.9 0.0016 19.0 0.9 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 RLN86725.1 - 0.00067 19.0 0.8 0.0029 16.9 0.5 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 RLN86725.1 - 0.0012 18.2 0.2 0.067 12.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RLN86725.1 - 0.0057 15.8 2.6 0.25 10.4 1.2 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.14 RLN86725.1 - 0.0085 14.8 4.4 0.048 12.4 1.5 2.8 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 RLN86725.1 - 0.0098 15.2 0.4 0.04 13.2 0.6 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 RLN86725.1 - 0.18 12.3 0.3 0.51 10.8 0.3 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 RLN86725.1 - 0.21 11.8 1.7 0.64 10.3 1.7 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 RLN86725.1 - 0.29 9.9 2.1 0.77 8.5 1.3 1.9 2 0 0 2 2 2 0 Tryptophan halogenase Ank_4 PF13637.6 RLN86726.1 - 0.017 15.7 0.2 0.085 13.5 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) FYVE PF01363.21 RLN86727.1 - 6.2e-12 45.5 6.3 1.6e-11 44.2 6.3 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE PF01363.21 RLN86728.1 - 3.4e-11 43.1 8.5 9.7e-11 41.6 8.5 1.8 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN86728.1 - 0.0015 18.8 3.1 0.0018 18.5 1.6 1.8 2 0 0 2 2 2 1 FYVE-type zinc finger MULE PF10551.9 RLN86730.1 - 4.4e-09 36.6 0.6 4.4e-09 36.6 0.6 2.4 3 0 0 3 3 3 1 MULE transposase domain Nop10p PF04135.12 RLN86732.1 - 5.3e-22 77.6 0.5 7.4e-22 77.1 0.5 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Ras PF00071.22 RLN86733.1 - 1.1e-23 83.6 0.2 5.6e-22 78.1 0.2 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RLN86733.1 - 6e-18 65.2 0.1 4.8e-17 62.3 0.1 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN86733.1 - 4.1e-05 23.1 0.1 0.0002 20.9 0.1 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 RLN86733.1 - 0.012 14.8 0.0 0.14 11.3 0.0 1.9 1 1 0 2 2 2 0 G-protein alpha subunit Pox_A32 PF04665.12 RLN86733.1 - 0.042 13.3 0.0 0.058 12.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein Septin PF00735.18 RLN86733.1 - 0.045 13.0 0.0 0.046 13.0 0.0 1.1 1 0 0 1 1 1 0 Septin TsaE PF02367.17 RLN86733.1 - 0.06 13.4 0.0 0.085 12.9 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 RLN86733.1 - 0.06 13.4 0.0 0.15 12.2 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 RLN86733.1 - 0.087 13.2 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 RLN86733.1 - 0.11 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 RLN86733.1 - 0.12 12.5 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RLN86733.1 - 0.13 12.0 0.1 0.2 11.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 RLN86733.1 - 0.14 11.3 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.22 RLN86733.1 - 0.17 11.0 0.0 0.23 10.6 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain SNF2_N PF00176.23 RLN86734.1 - 8.6e-46 156.3 0.0 1.4e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN86734.1 - 7.3e-24 84.3 0.0 1.4e-20 73.6 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain HDA2-3 PF11496.8 RLN86734.1 - 3.2e-06 26.5 0.1 6.4e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 RLN86734.1 - 1.1e-05 24.8 0.1 1.9e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase RNA_pol_L_2 PF13656.6 RLN86735.1 - 1.6e-24 85.5 0.0 2e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 RLN86735.1 - 2.7e-06 26.7 0.0 4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CorA PF01544.18 RLN86735.1 - 0.051 12.9 0.0 0.057 12.7 0.0 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Amino_oxidase PF01593.24 RLN86736.1 - 3e-17 63.1 0.1 1.2e-09 38.0 0.0 2.9 2 1 1 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RLN86736.1 - 5.3e-15 55.4 0.0 1.3e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RLN86736.1 - 6.1e-10 39.2 0.3 1e-06 28.6 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RLN86736.1 - 9.7e-10 38.1 0.4 7.1e-06 25.5 0.2 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RLN86736.1 - 7.8e-07 28.8 0.2 1.5e-06 27.8 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 RLN86736.1 - 2.7e-06 26.7 0.5 4.8e-06 25.9 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 RLN86736.1 - 3.1e-06 26.2 0.5 0.0036 16.1 0.3 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 RLN86736.1 - 6.9e-06 26.1 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 RLN86736.1 - 0.00028 20.1 0.6 0.0022 17.1 0.3 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 RLN86736.1 - 0.0004 19.7 0.2 0.00061 19.1 0.2 1.2 1 0 0 1 1 1 1 Thi4 family MCRA PF06100.11 RLN86736.1 - 0.00053 18.9 0.0 0.00088 18.2 0.0 1.3 1 0 0 1 1 1 1 MCRA family Pyr_redox_3 PF13738.6 RLN86736.1 - 0.0011 18.3 0.3 0.12 11.6 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RLN86736.1 - 0.0067 15.5 4.3 0.95 8.4 0.1 3.1 2 1 1 3 3 3 2 Lycopene cyclase protein Pyr_redox PF00070.27 RLN86736.1 - 0.0077 16.8 1.8 0.14 12.7 0.8 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RLN86736.1 - 0.012 14.9 0.8 0.021 14.1 0.8 1.3 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 RLN86737.1 - 2.8e-18 66.5 0.0 8.7e-10 38.5 0.0 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RLN86737.1 - 1.8e-15 56.9 0.0 5.4e-15 55.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RLN86737.1 - 7.8e-10 38.8 0.5 2.2e-06 27.5 0.8 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RLN86737.1 - 1e-09 38.0 0.4 8e-06 25.3 0.4 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RLN86737.1 - 2e-07 30.8 0.3 3.8e-07 29.8 0.2 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 RLN86737.1 - 1.8e-06 26.9 0.4 0.0032 16.2 0.6 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 RLN86737.1 - 3.1e-06 26.5 0.8 6e-06 25.6 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 RLN86737.1 - 8.3e-06 25.9 0.0 0.17 11.9 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding MCRA PF06100.11 RLN86737.1 - 0.00017 20.5 0.0 0.00031 19.7 0.0 1.4 1 0 0 1 1 1 1 MCRA family GIDA PF01134.22 RLN86737.1 - 0.00031 20.0 0.7 0.0022 17.1 0.5 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 RLN86737.1 - 0.00091 18.6 0.1 0.1 11.8 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 RLN86737.1 - 0.00098 18.4 0.3 0.0015 17.8 0.3 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 RLN86737.1 - 0.016 15.8 2.0 0.26 11.9 1.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RLN86737.1 - 0.017 14.2 4.7 0.93 8.5 0.1 3.0 2 1 1 3 3 3 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 RLN86737.1 - 0.025 13.8 1.0 0.048 12.9 1.0 1.4 1 0 0 1 1 1 0 FAD binding domain ubiquitin PF00240.23 RLN86738.1 - 7.3e-12 44.9 0.1 4e-11 42.5 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 RLN86738.1 - 1.4e-07 31.6 0.0 2.3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 RLN86738.1 - 4.8e-06 26.3 0.0 1.4e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 RLN86738.1 - 0.0002 22.0 0.0 0.0005 20.7 0.0 1.7 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukD DUF2407 PF10302.9 RLN86738.1 - 0.0012 19.3 0.0 0.0024 18.4 0.0 1.5 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain ANAPC3 PF12895.7 RLN86739.1 - 0.0026 18.0 1.0 0.12 12.6 0.2 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Yos9_DD PF17880.1 RLN86740.1 - 0.16 12.1 0.1 0.52 10.4 0.1 1.7 1 1 1 2 2 2 0 Yos9 dimerzation domain SnoaL_2 PF12680.7 RLN86741.1 - 0.0011 19.5 0.0 1.6 9.4 0.0 2.9 2 0 0 2 2 2 2 SnoaL-like domain Pepdidase_M14_N PF18027.1 RLN86741.1 - 0.15 12.4 0.3 0.87 10.0 0.1 2.2 2 0 0 2 2 2 0 Cytosolic carboxypeptidase N-terminal domain DUF1192 PF06698.11 RLN86741.1 - 0.43 10.7 1.8 34 4.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) bZIP_2 PF07716.15 RLN86741.1 - 1.5 9.0 9.2 4.2 7.5 6.0 2.7 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.17 RLN86742.1 - 0.011 16.2 7.2 0.011 16.2 7.2 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor SnoaL_2 PF12680.7 RLN86742.1 - 0.15 12.7 0.1 0.85 10.3 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like domain bZIP_2 PF07716.15 RLN86742.1 - 0.71 10.0 8.5 1.8 8.7 8.5 1.7 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 RLN86742.1 - 1.1 9.4 8.7 2.6 8.2 8.7 1.6 1 0 0 1 1 1 0 bZIP transcription factor MFS_1 PF07690.16 RLN86743.1 - 2.2e-14 53.2 43.0 1.2e-09 37.6 8.1 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily RINT1_TIP1 PF04437.13 RLN86744.1 - 1.8e-33 116.2 0.0 1.3e-29 103.5 0.0 4.0 1 1 0 1 1 1 1 RINT-1 / TIP-1 family Myticin-prepro PF10690.9 RLN86744.1 - 0.028 14.6 3.2 0.069 13.4 3.2 1.6 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel Pkinase PF00069.25 RLN86745.1 - 2.8e-44 151.5 0.0 3.5e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN86745.1 - 8.2e-29 100.7 0.0 1.1e-28 100.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN86745.1 - 0.0071 16.3 0.2 0.031 14.2 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN86745.1 - 0.0081 15.0 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 RLN86745.1 - 0.055 12.4 0.0 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 RLN86745.1 - 0.06 12.7 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family cNMP_binding PF00027.29 RLN86746.1 - 4e-12 46.0 0.1 3.8e-07 30.1 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN86746.1 - 0.0035 16.6 7.4 0.0055 16.0 7.4 1.3 1 0 0 1 1 1 1 Ion transport protein DUF3580 PF12117.8 RLN86746.1 - 0.2 11.9 0.1 0.2 11.9 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3580) RGS PF00615.19 RLN86747.1 - 1.3e-72 241.6 9.3 4.4e-21 75.3 0.2 4.9 5 0 0 5 5 5 4 Regulator of G protein signaling domain DnaJ PF00226.31 RLN86747.1 - 4e-05 23.7 0.0 8.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 RLN86747.1 - 0.00019 21.4 0.0 0.00019 21.4 0.0 2.2 3 0 0 3 3 3 1 Pam16 Acyl-CoA_dh_1 PF00441.24 RLN86749.1 - 2.3e-41 141.5 2.5 4e-41 140.7 2.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RLN86749.1 - 1.6e-26 92.3 0.0 3.2e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 RLN86749.1 - 1.6e-20 73.8 0.0 7.5e-20 71.7 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 RLN86749.1 - 3.3e-16 59.8 0.8 3.3e-16 59.8 0.8 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 RLN86749.1 - 0.049 13.3 0.1 0.13 11.9 0.1 1.6 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DHR-2 PF06920.13 RLN86750.1 - 1.1e-44 153.0 0.0 1.2e-42 146.3 0.0 2.2 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 RLN86750.1 - 5.6e-24 85.0 0.0 3.2e-23 82.5 0.0 2.0 1 1 1 2 2 2 1 C2 domain in Dock180 and Zizimin proteins zf-C3HC4_3 PF13920.6 RLN86751.1 - 6e-07 29.2 12.5 9.7e-07 28.6 12.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN86751.1 - 1.7e-05 24.6 12.8 2.9e-05 23.8 12.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Prolamin_like PF05617.11 RLN86752.1 - 0.11 12.7 0.0 0.91 9.7 0.0 2.4 2 0 0 2 2 2 0 Prolamin-like Baculo_RING PF05883.11 RLN86752.1 - 0.19 11.7 0.1 0.4 10.7 0.1 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-C3HC4_3 PF13920.6 RLN86753.1 - 1.7e-06 27.8 12.9 3.5e-06 26.8 12.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN86753.1 - 8.8e-05 22.3 12.4 0.00015 21.5 12.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 PDZ_6 PF17820.1 RLN86754.1 - 0.00065 19.5 0.0 0.036 13.9 0.1 2.8 2 0 0 2 2 2 1 PDZ domain Nup88 PF10168.9 RLN86754.1 - 0.77 7.5 3.8 1.3 6.8 3.8 1.2 1 0 0 1 1 1 0 Nuclear pore component DDE_1 PF03184.19 RLN86755.1 - 1.2e-17 64.1 0.0 1.1e-11 44.7 0.0 2.4 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN86755.1 - 2.9e-11 43.2 0.1 6.3e-11 42.1 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 RLN86755.1 - 0.0011 18.5 0.1 0.0023 17.5 0.1 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_32 PF13565.6 RLN86755.1 - 0.0017 18.9 0.3 1.3 9.7 0.0 3.1 1 1 1 2 2 2 2 Homeodomain-like domain UPF0020 PF01170.18 RLN86756.1 - 4.8e-15 55.8 0.0 5.9e-14 52.2 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 THUMP PF02926.17 RLN86756.1 - 5e-06 26.7 0.3 1.2e-05 25.5 0.1 1.6 2 0 0 2 2 2 1 THUMP domain Ubie_methyltran PF01209.18 RLN86756.1 - 0.00087 18.7 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 RLN86756.1 - 0.001 19.7 0.0 0.0021 18.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN86756.1 - 0.0021 18.7 0.0 0.0042 17.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN86756.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain SF-assemblin PF06705.11 RLN86757.1 - 1.1e-36 126.4 23.2 5.6e-29 101.2 17.6 2.0 1 1 1 2 2 2 2 SF-assemblin/beta giardin DUF3584 PF12128.8 RLN86757.1 - 0.00019 19.1 20.2 0.00024 18.8 20.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF5098 PF17023.5 RLN86757.1 - 0.00024 20.2 1.6 0.00024 20.2 1.6 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF5098) Prominin PF05478.11 RLN86757.1 - 0.011 13.8 4.9 0.015 13.3 4.9 1.2 1 0 0 1 1 1 0 Prominin GST_C PF00043.25 RLN86757.1 - 0.088 13.0 1.2 1.9 8.8 0.2 2.9 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Baculo_PEP_C PF04513.12 RLN86757.1 - 0.5 10.4 4.1 1.3 9.0 2.1 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Macoilin PF09726.9 RLN86757.1 - 0.74 8.3 13.5 0.36 9.3 11.7 1.4 1 1 0 1 1 1 0 Macoilin family Fungal_TACC PF12709.7 RLN86757.1 - 0.95 9.9 9.2 1.7 9.1 0.2 3.4 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins NPV_P10 PF05531.12 RLN86757.1 - 1.9 9.0 6.6 3.7 8.1 0.2 3.9 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein betaPIX_CC PF16523.5 RLN86757.1 - 2.2 8.1 16.0 0.56 10.1 5.6 3.2 1 1 2 3 3 3 0 betaPIX coiled coil Nup54 PF13874.6 RLN86757.1 - 3.4 7.8 20.0 0.18 11.9 9.1 3.2 1 1 1 3 3 3 0 Nucleoporin complex subunit 54 Syntaxin_2 PF14523.6 RLN86757.1 - 3.6 8.0 11.6 2.1 8.8 1.8 2.9 2 1 1 3 3 3 0 Syntaxin-like protein Apolipoprotein PF01442.18 RLN86757.1 - 4.2 7.2 24.6 0.76 9.6 18.7 2.3 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain IZUMO PF15005.6 RLN86757.1 - 6.9 7.2 8.0 1.2 9.7 1.9 2.6 1 1 2 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated DUF1043 PF06295.12 RLN86757.1 - 7.1 6.7 10.2 2.4 8.2 5.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) CREPT PF16566.5 RLN86757.1 - 9.8 6.3 17.1 0.13 12.4 5.1 2.9 2 1 2 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour FWWh PF14922.6 RLN86758.1 - 3e-18 66.2 0.1 5.9e-18 65.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function RIO1 PF01163.22 RLN86759.1 - 4e-28 98.3 0.1 4e-28 98.3 0.1 2.1 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 RLN86759.1 - 0.032 13.0 0.1 0.032 13.0 0.1 2.2 1 1 0 2 2 2 0 Fungal protein kinase Nop53 PF07767.11 RLN86759.1 - 0.078 12.4 25.7 0.15 11.5 25.7 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 RLN86759.1 - 0.08 11.2 19.5 0.1 10.9 19.5 1.1 1 0 0 1 1 1 0 CDC45-like protein ABC_tran PF00005.27 RLN86760.1 - 5.3e-16 59.4 0.0 1e-15 58.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 RLN86760.1 - 1.6e-06 27.7 7.3 2.2e-06 27.3 7.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_16 PF13191.6 RLN86760.1 - 8.3e-05 23.0 0.0 0.0024 18.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 RLN86760.1 - 0.0015 17.9 0.0 0.0028 16.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF815 PF05673.13 RLN86760.1 - 0.013 14.6 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 RLN86760.1 - 0.016 14.9 0.3 0.035 13.8 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN86760.1 - 0.028 14.7 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RLN86760.1 - 0.032 14.2 0.1 0.074 13.0 0.1 1.5 1 1 0 1 1 1 0 RsgA GTPase G-alpha PF00503.20 RLN86760.1 - 0.051 12.7 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_25 PF13481.6 RLN86760.1 - 0.089 12.4 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 RLN86760.1 - 0.13 12.3 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CbiX PF01903.17 RLN86763.1 - 5.3e-08 33.2 0.1 3.2e-05 24.2 0.1 3.3 2 1 0 2 2 2 2 CbiX NDK PF00334.19 RLN86765.1 - 6.8e-49 165.3 0.0 7.3e-37 126.4 0.0 3.4 3 0 0 3 3 3 2 Nucleoside diphosphate kinase ADK PF00406.22 RLN86765.1 - 0.038 14.1 0.0 41 4.2 0.0 3.5 3 0 0 3 3 3 0 Adenylate kinase Lipase_GDSL_2 PF13472.6 RLN86765.1 - 0.066 13.6 0.5 3 8.2 0.0 3.4 2 1 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase family Dpy-30 PF05186.13 RLN86765.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Dpy-30 motif zf-C3HC4_2 PF13923.6 RLN86767.1 - 6.5e-05 22.7 0.5 6.5e-05 22.7 0.5 4.0 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS1595 PF12760.7 RLN86767.1 - 0.00021 21.2 0.8 0.00021 21.2 0.8 2.8 3 0 0 3 3 3 1 Transposase zinc-ribbon domain IBR PF01485.21 RLN86767.1 - 0.00084 19.5 1.8 0.00084 19.5 1.8 2.8 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 RLN86767.1 - 0.0046 16.9 11.3 0.0046 16.9 11.3 2.7 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 RLN86767.1 - 0.008 16.3 3.5 0.008 16.3 3.5 3.7 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RLN86767.1 - 0.023 14.5 2.6 0.023 14.5 2.6 3.6 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 RLN86767.1 - 0.026 14.4 10.9 0.026 14.4 10.9 3.0 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.9 RLN86767.1 - 0.27 11.4 0.2 0.27 11.4 0.2 4.7 4 1 0 4 4 4 0 Uncharacterised protein family UPF0547 TerY_C PF15616.6 RLN86767.1 - 5.4 7.1 18.0 0.045 13.9 3.1 2.7 2 1 0 2 2 2 0 TerY-C metal binding domain zf-RING_6 PF14835.6 RLN86767.1 - 5.8 6.9 24.1 3.3 7.7 4.0 3.5 3 1 0 3 3 3 0 zf-RING of BARD1-type protein MIP-T3 PF10243.9 RLN86768.1 - 4e-05 23.6 0.0 9.8e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain EF-hand_1 PF00036.32 RLN86769.1 - 4.6e-12 44.6 1.0 1.5e-05 24.2 0.3 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN86769.1 - 1.9e-11 42.9 0.4 0.00022 20.9 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 RLN86769.1 - 7.1e-10 39.2 0.3 2e-09 37.7 0.3 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN86769.1 - 3.5e-09 35.7 2.4 0.00078 18.8 0.8 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RLN86769.1 - 1.4e-08 34.5 0.3 1.5e-06 27.9 0.2 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 RLN86769.1 - 0.0065 16.8 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_10 PF14788.6 RLN86769.1 - 0.078 12.8 1.0 0.48 10.3 0.1 2.3 1 1 1 2 2 2 0 EF hand DUF2624 PF11116.8 RLN86769.1 - 0.1 13.5 0.0 0.22 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) GAS PF13851.6 RLN86770.1 - 0.029 13.7 15.4 0.46 9.8 11.2 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding NHR2 PF08788.11 RLN86770.1 - 0.073 12.8 1.0 0.19 11.5 0.6 1.9 1 1 0 1 1 1 0 NHR2 domain like VWA PF00092.28 RLN86771.1 - 0.00045 20.5 0.0 0.00084 19.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RLN86771.1 - 0.017 15.8 0.0 0.078 13.6 0.0 2.3 1 0 0 1 1 1 0 von Willebrand factor type A domain CDT1_C PF16679.5 RLN86771.1 - 0.054 13.9 0.6 0.31 11.5 0.1 2.3 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain HEM4 PF02602.15 RLN86772.1 - 7.2e-28 97.5 0.3 9.9e-28 97.1 0.3 1.2 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TraW_N PF12477.8 RLN86773.1 - 0.064 13.2 0.8 0.064 13.2 0.8 3.9 3 0 0 3 3 3 0 Sex factor F TraW protein N terminal EF-hand_5 PF13202.6 RLN86773.1 - 1.2 8.7 13.8 10 5.8 0.7 3.5 3 0 0 3 3 3 0 EF hand EF-hand_1 PF00036.32 RLN86773.1 - 2.4 7.9 8.0 48 3.8 0.2 3.8 3 0 0 3 3 3 0 EF hand TSP_3 PF02412.18 RLN86773.1 - 5.6 6.7 20.9 8 6.2 2.1 4.1 3 0 0 3 3 3 0 Thrombospondin type 3 repeat SNF2_N PF00176.23 RLN86774.1 - 3.4e-60 203.6 0.4 8.9e-60 202.2 0.0 1.7 2 1 1 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN86774.1 - 8.4e-20 71.2 0.0 2.6e-19 69.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-HC5HC2H_2 PF13832.6 RLN86774.1 - 7e-19 68.0 7.2 7e-19 68.0 7.2 2.6 1 1 1 2 2 2 1 PHD-zinc-finger like domain Chromo PF00385.24 RLN86774.1 - 1.5e-17 63.3 4.6 1e-08 34.9 2.0 3.1 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain zf-HC5HC2H PF13771.6 RLN86774.1 - 1.6e-16 60.3 10.8 3e-16 59.4 0.9 2.6 2 0 0 2 2 2 1 PHD-like zinc-binding domain ResIII PF04851.15 RLN86774.1 - 4.4e-12 46.3 0.0 1.9e-10 41.0 0.0 3.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 RLN86774.1 - 7.2e-07 28.7 0.0 1.7e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 QLQ PF08880.11 RLN86774.1 - 1.1e-05 25.1 1.1 2.2e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 QLQ PHD_2 PF13831.6 RLN86774.1 - 0.00056 19.4 0.9 0.00056 19.4 0.9 2.0 2 0 0 2 2 2 1 PHD-finger PDZ_2 PF13180.6 RLN86774.1 - 0.00074 19.8 0.0 0.028 14.7 0.0 2.8 2 0 0 2 2 2 1 PDZ domain DEAD PF00270.29 RLN86774.1 - 0.0017 18.2 0.0 0.0052 16.6 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RLN86774.1 - 0.041 14.2 0.1 0.67 10.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain PHD PF00628.29 RLN86774.1 - 0.079 12.9 22.6 0.037 13.9 9.8 2.6 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.16 RLN86774.1 - 0.18 12.0 2.6 0.73 10.1 2.6 2.0 1 0 0 1 1 1 0 FYVE-type zinc finger TFIIF_beta PF02270.15 RLN86775.1 - 4.5e-07 29.9 0.1 9.6e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain KASH_CCD PF14662.6 RLN86776.1 - 0.011 15.6 4.9 0.011 15.6 4.9 1.8 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Cnd1_N PF12922.7 RLN86776.1 - 0.027 14.3 0.0 0.071 13.0 0.0 1.7 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term DUF1827 PF08860.10 RLN86776.1 - 0.052 13.8 0.1 0.19 12.0 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1827) BLOC1_2 PF10046.9 RLN86776.1 - 0.13 12.6 1.6 14 6.0 0.1 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMPIT PF07851.13 RLN86776.1 - 4.3 6.5 5.3 1.9 7.6 3.1 1.5 2 0 0 2 2 2 0 TMPIT-like protein Mlh1_C PF16413.5 RLN86778.1 - 3.6e-70 236.4 3.2 2.8e-69 233.5 0.1 2.9 2 1 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 RLN86778.1 - 1.3e-22 79.7 0.4 2.7e-22 78.7 0.4 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 RLN86778.1 - 4.5e-12 46.0 0.1 1.3e-11 44.5 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 RLN86778.1 - 1e-07 32.5 0.0 2.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.25 RLN86779.1 - 6.6e-57 192.9 0.0 2e-56 191.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN86779.1 - 1.8e-27 96.3 0.0 4.5e-25 88.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase PAS PF00989.25 RLN86779.1 - 3.9e-09 36.5 0.0 7.9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 RLN86779.1 - 4.1e-05 23.8 0.0 0.0001 22.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 RLN86779.1 - 4.3e-05 23.7 0.0 0.0001 22.5 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 RLN86779.1 - 0.0011 19.0 0.0 0.0029 17.6 0.0 1.7 1 0 0 1 1 1 1 PAS domain Kdo PF06293.14 RLN86779.1 - 0.0024 17.3 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN86779.1 - 0.013 15.5 0.2 0.029 14.3 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Rz1 PF06085.11 RLN86779.1 - 0.49 10.2 5.0 2.1 8.2 0.0 3.3 3 0 0 3 3 3 0 Lipoprotein Rz1 precursor Aminotran_1_2 PF00155.21 RLN86780.1 - 1.6e-57 195.3 0.0 4.8e-55 187.2 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II PDT PF00800.18 RLN86780.1 - 1e-11 45.0 0.0 6.1e-11 42.5 0.0 2.2 2 0 0 2 2 2 1 Prephenate dehydratase Erythrovirus_X PF06795.11 RLN86780.1 - 0.047 14.0 0.4 0.61 10.4 0.0 2.7 3 0 0 3 3 3 0 Erythrovirus X protein Ank_2 PF12796.7 RLN86781.1 - 5.2e-84 276.9 11.8 1.3e-18 67.3 0.5 7.6 4 2 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN86781.1 - 6.7e-64 211.5 9.2 2.2e-13 50.4 0.1 9.7 5 2 5 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN86781.1 - 8.7e-59 188.6 15.4 5.1e-05 23.4 0.0 14.8 14 1 0 14 14 14 11 Ankyrin repeat Ank PF00023.30 RLN86781.1 - 1.5e-57 189.7 18.5 2.2e-06 27.9 0.0 12.8 13 0 0 13 13 13 10 Ankyrin repeat Ank_5 PF13857.6 RLN86781.1 - 4.3e-52 173.5 27.8 3.2e-09 36.9 0.1 13.4 3 3 12 15 15 15 11 Ankyrin repeats (many copies) CUE PF02845.16 RLN86781.1 - 0.27 11.0 2.7 6 6.7 0.0 3.8 4 0 0 4 4 4 0 CUE domain DUF4355 PF14265.6 RLN86781.1 - 0.88 9.8 2.9 19 5.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4355) Efg1 PF10153.9 RLN86782.1 - 0.031 14.6 0.1 0.038 14.3 0.1 1.2 1 0 0 1 1 1 0 rRNA-processing protein Efg1 Tmemb_40 PF10160.9 RLN86782.1 - 0.11 12.0 0.1 0.13 11.7 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein Reovirus_Mu2 PF07781.11 RLN86782.1 - 0.11 10.8 0.0 0.12 10.8 0.0 1.0 1 0 0 1 1 1 0 Reovirus minor core protein Mu-2 Ribosomal_60s PF00428.19 RLN86783.1 - 3.5e-17 62.8 12.3 4.6e-17 62.4 12.3 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein NRD1_2 PF01995.16 RLN86783.1 - 0.14 11.4 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 NrpR regulatory domains NRD1 and 2 DHHC PF01529.20 RLN86784.1 - 1.4e-10 41.4 7.0 1.9e-10 40.9 7.0 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase DASH_Dad2 PF08654.10 RLN86784.1 - 0.0062 16.9 0.3 0.015 15.7 0.3 1.6 1 0 0 1 1 1 1 DASH complex subunit Dad2 Totivirus_coat PF05518.11 RLN86784.1 - 0.12 10.4 2.8 0.17 9.9 2.8 1.1 1 0 0 1 1 1 0 Totivirus coat protein WD40 PF00400.32 RLN86785.1 - 0.014 16.2 2.2 2.3 9.2 0.1 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat zf-HIT PF04438.16 RLN86785.1 - 1.1 9.1 11.8 2 8.4 11.8 1.4 1 0 0 1 1 1 0 HIT zinc finger AvrL567-A PF11529.8 RLN86786.1 - 0.069 13.3 0.2 0.17 12.1 0.1 1.8 2 0 0 2 2 2 0 Melampsora lini avirulence protein AvrL567-A FAM76 PF16046.5 RLN86786.1 - 0.16 11.3 0.8 0.2 11.0 0.8 1.1 1 0 0 1 1 1 0 FAM76 protein LSM PF01423.22 RLN86787.1 - 6.8e-19 67.3 0.0 9.7e-19 66.8 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RLN86787.1 - 0.00083 19.4 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain TPR_2 PF07719.17 RLN86788.1 - 0.0072 16.4 0.1 0.0072 16.4 0.1 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat Peptidase_Mx PF15887.5 RLN86788.1 - 0.023 14.1 5.0 0.016 14.6 1.4 2.1 2 0 0 2 2 2 0 Putative zinc-binding metallo-peptidase DUF2481 PF10654.9 RLN86788.1 - 0.1 12.6 0.2 0.73 9.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2481) TPR_1 PF00515.28 RLN86788.1 - 0.12 12.2 11.4 0.16 11.9 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 RLN86788.1 - 0.55 10.6 3.6 1.9 8.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S17 PF00366.20 RLN86790.1 - 6.7e-30 103.0 1.3 7.5e-30 102.8 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S17 Prp18 PF02840.15 RLN86790.1 - 0.018 15.1 0.1 0.025 14.6 0.1 1.2 1 0 0 1 1 1 0 Prp18 domain Ubiquitin_2 PF14560.6 RLN86791.1 - 5e-25 87.8 0.0 8.4e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 RLN86791.1 - 1.4e-21 76.3 3.6 2.2e-21 75.6 3.6 1.3 1 0 0 1 1 1 1 CAP-Gly domain Transket_pyr PF02779.24 RLN86792.1 - 1.3e-56 191.1 0.0 2.1e-56 190.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 RLN86792.1 - 4.3e-48 162.9 0.0 7.6e-48 162.1 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 RLN86792.1 - 3.1e-23 82.2 0.1 6.2e-21 74.6 0.0 2.3 1 1 1 2 2 2 2 Dehydrogenase E1 component Erf4 PF10256.9 RLN86792.1 - 0.076 13.1 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Hemopexin PF00045.19 RLN86792.1 - 0.16 11.9 0.0 0.47 10.4 0.0 1.7 1 0 0 1 1 1 0 Hemopexin Vps16_C PF04840.12 RLN86793.1 - 4.6e-16 58.8 0.0 9.8e-14 51.1 0.0 2.2 1 1 0 2 2 2 2 Vps16, C-terminal region COQ9 PF08511.11 RLN86795.1 - 2.4e-35 120.1 0.2 5.4e-35 119.0 0.2 1.6 1 0 0 1 1 1 1 COQ9 MORN PF02493.20 RLN86796.1 - 1.8e-21 74.7 29.5 9.3e-05 22.1 0.1 7.4 8 1 0 8 8 8 6 MORN repeat PP2C PF00481.21 RLN86797.1 - 1.8e-61 208.0 0.2 2.7e-61 207.5 0.2 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RLN86797.1 - 0.004 16.8 2.4 0.0054 16.4 1.6 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C AlgF PF11182.8 RLN86797.1 - 0.07 12.9 0.1 0.2 11.4 0.1 1.8 2 0 0 2 2 2 0 Alginate O-acetyl transferase AlgF ACT PF01842.25 RLN86797.1 - 0.15 11.8 0.2 2.2 8.1 0.0 2.5 2 0 0 2 2 2 0 ACT domain PseudoU_synth_1 PF01416.20 RLN86798.1 - 9.3e-32 109.7 0.1 4.1e-28 98.0 0.0 2.7 2 1 0 2 2 2 2 tRNA pseudouridine synthase Mtc PF03820.17 RLN86800.1 - 1.1e-60 205.4 0.0 6e-31 107.6 0.0 3.0 1 1 2 3 3 3 3 Tricarboxylate carrier ssDNA_TraI_N PF18272.1 RLN86800.1 - 0.096 12.7 0.1 10 6.2 0.1 2.3 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain DNA_primase_lrg PF04104.14 RLN86801.1 - 6.8e-61 206.0 0.0 8.4e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit 2OG-FeII_Oxy PF03171.20 RLN86802.1 - 1.1e-05 25.9 0.0 2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aa_trans PF01490.18 RLN86803.1 - 4.3e-44 150.9 14.3 6.7e-44 150.2 14.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 RLN86804.1 - 1.4e-44 152.4 17.8 2.1e-44 151.9 17.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 RLN86805.1 - 1e-41 143.0 14.0 1.7e-41 142.3 14.0 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 RLN86806.1 - 1.9e-44 152.0 14.8 2.9e-44 151.4 14.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1182 PF06681.13 RLN86806.1 - 0.081 12.5 4.8 0.035 13.7 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1182) Mlo PF03094.15 RLN86807.1 - 0.0053 15.2 13.8 0.024 13.0 0.2 3.7 2 1 2 4 4 4 2 Mlo family HXXEE PF13787.6 RLN86807.1 - 5.8 7.8 11.7 12 6.8 4.8 3.3 3 0 0 3 3 3 0 Protein of unknown function with HXXEE motif ORC2 PF04084.14 RLN86808.1 - 4.4e-57 193.5 0.0 6.1e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 DUF4393 PF14337.6 RLN86808.1 - 0.098 12.5 0.0 0.42 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4393) DUF2052 PF09747.9 RLN86808.1 - 0.89 9.6 9.4 1.9 8.6 9.4 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CENP-B_dimeris PF09026.10 RLN86808.1 - 1.1 9.6 4.4 3.6 8.0 4.4 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DEAD PF00270.29 RLN86809.1 - 3.8e-06 26.8 0.4 0.014 15.2 0.1 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN86809.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.8 1 1 0 1 1 1 0 Helicase conserved C-terminal domain CBS PF00571.28 RLN86809.1 - 0.057 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 CBS domain Aa_trans PF01490.18 RLN86810.1 - 1.8e-38 132.3 20.8 2.7e-38 131.8 20.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ATPase_gene1 PF09527.10 RLN86810.1 - 3.6 7.8 10.0 2.5 8.3 4.4 3.3 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Flp1_like PF16982.5 RLN86810.1 - 10 5.6 13.1 0.043 13.2 3.3 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain Aa_trans PF01490.18 RLN86811.1 - 6.2e-40 137.2 18.9 1.1e-39 136.3 18.9 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein LapA_dom PF06305.11 RLN86811.1 - 0.51 10.2 1.9 1.4 8.8 0.1 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain WASH_WAHD PF11945.8 RLN86813.1 - 4.8e-41 141.2 0.0 4.8e-41 141.2 0.0 1.4 2 0 0 2 2 2 1 WAHD domain of WASH complex DUF3464 PF11947.8 RLN86813.1 - 0.09 12.5 0.2 0.09 12.5 0.2 1.9 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 HrpB7 PF09486.10 RLN86813.1 - 2.7 8.4 14.5 0.84 10.0 2.1 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Mpv17_PMP22 PF04117.12 RLN86814.1 - 8.9e-22 77.1 0.3 1.4e-21 76.5 0.3 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family IQ PF00612.27 RLN86815.1 - 1.4e-22 77.3 58.5 0.00069 19.2 0.0 13.9 13 0 0 13 13 13 11 IQ calmodulin-binding motif BolA PF01722.18 RLN86815.1 - 0.0036 17.6 0.0 0.017 15.4 0.0 2.2 1 0 0 1 1 1 1 BolA-like protein Mpv17_PMP22 PF04117.12 RLN86816.1 - 8.9e-21 73.9 1.0 2e-20 72.7 0.7 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family UPF0242 PF06785.11 RLN86818.1 - 0.15 12.2 5.6 0.3 11.2 5.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SRP-alpha_N PF04086.13 RLN86818.1 - 5.2 6.9 12.0 7.7 6.3 12.0 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal EccE PF11203.8 RLN86819.1 - 0.042 14.2 0.3 0.15 12.4 0.3 1.9 1 0 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE HalX PF08663.10 RLN86819.1 - 0.39 11.1 8.2 0.29 11.5 1.9 2.6 2 0 0 2 2 2 0 HalX domain CRC_subunit PF08624.10 RLN86821.1 - 0.0094 16.4 0.1 0.021 15.2 0.1 1.5 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit GTP_EFTU PF00009.27 RLN86824.1 - 0.0012 18.4 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU PF00009.27 RLN86825.1 - 4e-37 127.6 0.0 6.1e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 RLN86825.1 - 6e-10 39.0 0.0 1.3e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 RLN86825.1 - 4.3e-07 30.2 0.2 8.5e-07 29.3 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RLN86825.1 - 0.0023 18.0 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DDE_1 PF03184.19 RLN86826.1 - 4.5e-19 68.8 0.0 5.7e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF659 PF04937.15 RLN86828.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 RLN86828.1 - 0.066 13.0 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Methyltransf_PK PF05891.12 RLN86828.1 - 0.091 12.3 0.0 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase ATP-synt_D PF01813.17 RLN86829.1 - 7.2e-29 101.0 1.9 7.2e-29 101.0 1.9 1.7 1 1 1 2 2 2 1 ATP synthase subunit D DUF573 PF04504.14 RLN86829.1 - 0.36 11.5 2.8 0.43 11.3 0.1 2.3 2 1 0 3 3 3 0 Protein of unknown function, DUF573 RabGAP-TBC PF00566.18 RLN86830.1 - 0.014 15.1 0.0 2.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Rab-GTPase-TBC domain MyTH4 PF00784.17 RLN86832.1 - 9.4e-23 80.8 0.0 2.6e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 MyTH4 domain FERM_M PF00373.18 RLN86832.1 - 3.7e-13 49.9 0.1 2.2e-12 47.4 0.0 2.1 2 0 0 2 2 2 1 FERM central domain Aa_trans PF01490.18 RLN86833.1 - 2.1e-69 234.2 21.1 2.7e-69 233.8 21.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CCB1 PF12046.8 RLN86833.1 - 0.058 12.7 0.1 0.18 11.2 0.1 1.8 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B PolyA_pol PF01743.20 RLN86834.1 - 1.7e-26 93.1 0.1 4.9e-26 91.6 0.1 1.8 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 RLN86834.1 - 0.00041 20.0 0.1 0.00084 19.0 0.1 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Bmt2 PF11968.8 RLN86835.1 - 9.1e-49 166.3 0.0 1.2e-48 165.9 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 RLN86835.1 - 3.1e-05 23.9 0.0 0.0003 20.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain DUF4670 PF15709.5 RLN86835.1 - 0.022 14.1 4.0 0.029 13.7 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) Methyltransf_12 PF08242.12 RLN86835.1 - 0.11 13.2 0.0 0.44 11.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain DUF4665 PF15679.5 RLN86835.1 - 0.3 11.7 3.0 0.83 10.3 2.3 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4665) Lyase_1 PF00206.20 RLN86836.1 - 1.2e-112 376.3 0.0 2.5e-112 375.3 0.0 1.5 1 0 0 1 1 1 1 Lyase LRR_6 PF13516.6 RLN86836.1 - 3.4e-14 51.6 22.5 7e-05 22.6 0.3 8.9 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.7 RLN86836.1 - 2 8.9 16.4 1.3 9.6 0.3 5.8 5 2 3 8 8 8 0 Leucine Rich repeats (2 copies) Glyco_transf_41 PF13844.6 RLN86837.1 - 2.4e-50 171.3 0.2 1.1e-42 146.1 0.1 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 RLN86837.1 - 9.1e-17 59.8 5.6 0.022 14.8 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 RLN86837.1 - 5.2e-16 57.7 0.0 0.27 11.1 0.0 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 RLN86837.1 - 5.8e-11 42.7 9.6 4.4e-06 27.1 1.5 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 RLN86837.1 - 6.2e-11 42.2 16.3 0.1 13.4 0.2 5.9 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 RLN86837.1 - 1.8e-10 41.0 11.6 0.0026 18.0 1.2 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 RLN86837.1 - 1e-08 35.7 10.4 0.0011 19.6 1.6 5.2 2 1 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN86837.1 - 1.4e-07 31.1 0.0 0.77 10.1 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN86837.1 - 2.6e-06 27.0 6.4 0.29 11.2 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN86837.1 - 1e-05 25.5 8.9 0.0079 16.3 1.8 3.8 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 RLN86837.1 - 5.2e-05 23.6 5.7 1 10.1 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN86837.1 - 5.4e-05 22.8 4.9 0.0036 16.9 0.1 4.4 4 1 1 5 5 5 1 TPR repeat TPR_21 PF09976.9 RLN86837.1 - 6.8e-05 22.7 3.5 0.00014 21.7 3.1 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 RLN86837.1 - 0.00038 20.6 0.6 0.045 14.0 0.1 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 RLN86837.1 - 0.0017 18.6 0.0 3.3 8.3 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat SNAP PF14938.6 RLN86837.1 - 0.0026 17.2 0.3 0.0065 15.9 0.3 1.7 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_20 PF14561.6 RLN86837.1 - 0.038 14.3 4.5 13 6.2 0.0 4.0 3 1 2 5 5 4 0 Tetratricopeptide repeat NARP1 PF12569.8 RLN86837.1 - 0.055 12.4 0.2 0.16 10.8 0.1 1.5 1 1 0 1 1 1 0 NMDA receptor-regulated protein 1 HydF_tetramer PF18133.1 RLN86837.1 - 0.057 13.2 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 1 0 Hydrogen maturase F tetramerization domain TPR_10 PF13374.6 RLN86837.1 - 6.3 6.8 15.8 12 5.9 0.0 5.3 7 0 0 7 7 5 0 Tetratricopeptide repeat Pkinase PF00069.25 RLN86838.1 - 2e-26 92.9 0.0 2.7e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN86838.1 - 1.8e-08 34.0 0.0 2.7e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN86838.1 - 0.0065 15.8 0.0 0.0087 15.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like KHA PF11834.8 RLN86839.1 - 1.1e-09 38.2 0.0 1.7e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel Pkinase PF00069.25 RLN86839.1 - 0.00014 21.3 0.0 0.00018 21.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain UQ_con PF00179.26 RLN86840.1 - 7.8e-28 96.9 0.0 9e-28 96.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF268 PF03269.14 RLN86841.1 - 9e-19 68.0 0.0 1.6e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Caenorhabditis protein of unknown function, DUF268 PH PF00169.29 RLN86842.1 - 1.4e-06 28.8 0.0 2.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN86842.1 - 0.0036 17.7 0.2 0.046 14.1 0.2 2.0 1 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 RLN86842.1 - 0.15 12.4 2.3 1.7 9.0 2.3 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain Ephrin_rec_like PF07699.13 RLN86843.1 - 2.6e-05 23.9 3.7 2.6e-05 23.9 3.7 37.3 24 9 13 37 37 37 28 Putative ephrin-receptor like Invasin_D3 PF09134.10 RLN86844.1 - 9.6 6.6 10.0 7.9 6.9 0.5 2.7 2 0 0 2 2 2 0 Invasin, domain 3 WD40 PF00400.32 RLN86845.1 - 1.3e-40 136.6 18.9 2.7e-05 24.9 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN86845.1 - 1.2e-10 41.5 0.3 0.061 13.6 0.1 5.0 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RLN86845.1 - 1.9e-05 24.7 0.0 0.00047 20.1 0.0 2.8 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 RLN86845.1 - 0.00038 19.1 0.2 0.0015 17.1 0.1 1.9 1 1 0 1 1 1 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 RLN86845.1 - 0.003 16.6 0.3 5.1 6.0 0.0 3.7 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Str_synth PF03088.16 RLN86845.1 - 0.12 12.5 0.0 0.49 10.6 0.0 1.9 1 1 1 2 2 2 0 Strictosidine synthase PQQ_3 PF13570.6 RLN86845.1 - 1.7 9.3 4.6 17 6.0 0.4 3.8 2 1 1 3 3 3 0 PQQ-like domain Ank_5 PF13857.6 RLN86848.1 - 0.053 13.9 0.1 6.2 7.3 0.0 3.1 2 1 1 3 3 3 0 Ankyrin repeats (many copies) PX PF00787.24 RLN86855.1 - 0.0044 17.0 0.0 0.0066 16.4 0.0 1.2 1 0 0 1 1 1 1 PX domain PX PF00787.24 RLN86856.1 - 0.048 13.6 0.1 0.072 13.1 0.1 1.4 1 0 0 1 1 1 0 PX domain Kinesin PF00225.23 RLN86857.1 - 1.8e-12 46.8 0.0 3.1e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain zf-rbx1 PF12678.7 RLN86857.1 - 7.5e-05 22.9 7.9 7.5e-05 22.9 7.9 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain PX PF00787.24 RLN86857.1 - 0.00096 19.1 0.1 0.0018 18.2 0.1 1.4 1 0 0 1 1 1 1 PX domain zf-ANAPC11 PF12861.7 RLN86857.1 - 0.001 19.1 3.1 0.0072 16.3 2.5 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 RLN86857.1 - 0.0011 19.3 9.5 0.0011 19.3 9.5 2.2 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN86857.1 - 0.0011 18.8 9.2 0.0011 18.8 9.2 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN86857.1 - 0.011 15.6 9.3 0.011 15.6 9.3 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 RLN86857.1 - 0.34 10.8 13.1 0.094 12.6 8.4 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN86857.1 - 4 7.5 11.8 1.3 9.1 6.8 2.5 2 0 0 2 2 2 0 RING-type zinc-finger PX PF00787.24 RLN86858.1 - 0.00018 21.4 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 PX domain SprT-like PF10263.9 RLN86858.1 - 0.058 13.2 0.2 0.087 12.7 0.2 1.3 1 1 0 1 1 1 0 SprT-like family zf-C3HC4_2 PF13923.6 RLN86859.1 - 3.2e-08 33.3 2.7 1.3e-07 31.3 2.7 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN86859.1 - 3.3e-06 27.3 2.1 3.3e-06 27.3 2.1 2.1 3 0 0 3 3 2 1 Ring finger domain zf-rbx1 PF12678.7 RLN86859.1 - 1.2e-05 25.5 0.5 1.2e-05 25.5 0.5 2.2 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RLN86859.1 - 1.3e-05 24.9 2.4 1.3e-05 24.9 2.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN86859.1 - 7.7e-05 22.6 3.8 0.00029 20.7 3.8 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 RLN86859.1 - 0.0013 18.4 4.1 0.0016 18.2 0.8 2.5 2 0 0 2 2 2 1 RING-like zinc finger PX PF00787.24 RLN86859.1 - 0.0046 16.9 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 PX domain zf-C3HC4_3 PF13920.6 RLN86859.1 - 0.0054 16.6 1.7 0.015 15.1 1.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.10 RLN86859.1 - 0.023 14.8 0.8 0.074 13.2 0.8 1.8 1 0 0 1 1 1 0 Zinc ribbon domain zf-RING_UBOX PF13445.6 RLN86859.1 - 0.031 14.3 0.5 0.031 14.3 0.5 2.7 2 1 1 3 3 3 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 RLN86859.1 - 0.085 12.9 1.5 0.45 10.6 0.2 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 RLN86859.1 - 0.15 12.1 3.0 0.51 10.4 3.0 1.9 1 0 0 1 1 1 0 Zinc-finger zf-RING-like PF08746.11 RLN86859.1 - 2.2 8.6 7.2 0.5 10.7 3.3 2.0 2 0 0 2 2 2 0 RING-like domain SR-25 PF10500.9 RLN86859.1 - 8.2 6.0 7.9 1.1 8.9 3.5 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-rbx1 PF12678.7 RLN86860.1 - 4.7e-06 26.8 3.0 4.7e-06 26.8 3.0 2.7 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 RLN86860.1 - 1.8e-05 24.9 1.8 1.8e-05 24.9 1.8 3.3 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN86860.1 - 3.8e-05 23.4 4.9 3.8e-05 23.4 4.9 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN86860.1 - 0.00022 21.0 4.5 0.00022 21.0 4.5 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN86860.1 - 0.0055 16.4 1.6 0.02 14.7 1.6 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 RLN86860.1 - 0.0065 16.5 2.9 0.025 14.6 2.9 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN86860.1 - 0.013 15.4 10.8 0.013 15.4 10.8 2.8 3 1 1 4 4 4 0 zinc-RING finger domain TetR_C_7 PF14246.6 RLN86860.1 - 0.054 13.5 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain FIST PF08495.10 RLN86860.1 - 0.095 12.7 0.0 0.21 11.6 0.0 1.5 1 1 0 1 1 1 0 FIST N domain zf-Nse PF11789.8 RLN86860.1 - 0.55 10.1 6.6 0.12 12.2 1.7 2.4 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 RLN86860.1 - 0.58 10.2 4.7 1.6 8.8 1.2 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 RLN86860.1 - 1.6 8.7 8.8 0.69 9.9 5.1 2.3 2 0 0 2 2 2 0 PHD-finger Zn-ribbon_8 PF09723.10 RLN86860.1 - 2.6 8.3 6.9 1.3 9.2 3.4 2.3 2 0 0 2 2 2 0 Zinc ribbon domain PX PF00787.24 RLN86861.1 - 0.0034 17.3 0.0 0.005 16.8 0.0 1.2 1 0 0 1 1 1 1 PX domain zf-C3HC4_2 PF13923.6 RLN86862.1 - 1.7e-06 27.8 0.9 1.7e-06 27.8 0.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN86862.1 - 6.6e-06 26.4 1.5 6.6e-06 26.4 1.5 2.6 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 RLN86862.1 - 7.6e-06 26.1 7.1 4.5e-05 23.6 6.5 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RLN86862.1 - 0.00085 19.1 6.3 0.0032 17.3 6.3 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN86862.1 - 0.0031 17.4 9.3 0.0073 16.2 7.4 2.4 1 1 1 2 2 2 1 zinc-RING finger domain PX PF00787.24 RLN86862.1 - 0.0046 16.9 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 PX domain zf-RING_11 PF17123.5 RLN86862.1 - 0.0099 15.6 0.1 0.0099 15.6 0.1 3.2 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_UBOX PF13445.6 RLN86862.1 - 0.02 14.9 0.7 0.02 14.9 0.7 2.3 2 1 0 2 2 2 0 RING-type zinc-finger zf-Nse PF11789.8 RLN86862.1 - 0.056 13.3 0.4 0.35 10.7 0.7 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 RLN86862.1 - 2.9 8.1 7.1 0.15 12.3 0.9 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 RLN86862.1 - 7.8 6.6 6.6 45 4.2 6.6 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RLN86862.1 - 9.4 6.2 10.9 0.17 11.7 2.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Myb_DNA-binding PF00249.31 RLN86864.1 - 1e-39 134.4 10.6 1.6e-14 53.8 0.3 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN86864.1 - 1e-31 108.9 4.5 8.2e-14 51.6 0.0 3.3 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 RLN86864.1 - 0.00045 20.2 0.0 0.28 11.2 0.0 3.1 1 1 2 3 3 3 1 SLIDE MADF_DNA_bdg PF10545.9 RLN86864.1 - 0.0047 17.2 3.7 0.68 10.3 0.1 3.3 2 1 1 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_7 PF15963.5 RLN86864.1 - 0.073 13.0 0.0 0.67 9.9 0.0 2.3 2 1 1 3 3 3 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 RLN86864.1 - 0.2 12.1 5.4 17 5.8 0.2 3.7 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain AAA_6 PF12774.7 RLN86865.1 - 3e-120 401.1 0.0 6.5e-118 393.4 0.0 3.7 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN86865.1 - 3.3e-98 329.4 3.4 3.3e-98 329.4 3.4 4.2 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 RLN86865.1 - 4.8e-70 235.1 0.0 2.7e-69 232.6 0.0 2.5 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_8 PF12780.7 RLN86865.1 - 9.6e-51 172.6 0.0 1.1e-48 165.9 0.0 3.7 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_5 PF07728.14 RLN86865.1 - 3.8e-36 124.1 0.0 5.2e-23 81.6 0.0 5.3 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 RLN86865.1 - 1.3e-35 122.1 0.0 1.1e-31 109.3 0.1 3.1 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain AAA_7 PF12775.7 RLN86865.1 - 3.9e-30 104.7 4.8 5.1e-27 94.5 0.0 3.7 4 0 0 4 4 3 2 P-loop containing dynein motor region MT PF12777.7 RLN86865.1 - 6.5e-30 104.3 5.3 1.5e-29 103.1 5.3 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 RLN86865.1 - 2.3e-14 53.5 0.1 5.3e-14 52.4 0.1 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain DHC_N1 PF08385.12 RLN86865.1 - 5.9e-11 41.7 4.2 2.9e-10 39.4 0.2 3.3 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_16 PF13191.6 RLN86865.1 - 1.1e-07 32.4 13.7 0.052 13.9 0.0 8.0 8 0 0 8 8 6 2 AAA ATPase domain AAA_22 PF13401.6 RLN86865.1 - 1.1e-07 32.2 2.6 0.51 10.6 0.0 5.4 5 0 0 5 5 4 2 AAA domain AAA PF00004.29 RLN86865.1 - 1.1e-06 29.1 0.0 0.3 11.5 0.0 5.0 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 RLN86865.1 - 4.1e-05 23.4 0.1 0.18 11.5 0.0 3.8 3 0 0 3 3 3 2 IstB-like ATP binding protein RsgA_GTPase PF03193.16 RLN86865.1 - 6.6e-05 22.9 7.0 0.024 14.5 0.0 5.2 5 0 0 5 5 5 1 RsgA GTPase AAA_33 PF13671.6 RLN86865.1 - 0.00011 22.3 0.1 1.4 9.1 0.0 4.1 4 0 0 4 4 3 1 AAA domain AAA_24 PF13479.6 RLN86865.1 - 0.00015 21.6 0.0 0.13 12.0 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 RLN86865.1 - 0.00058 19.6 0.2 0.35 10.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 RLN86865.1 - 0.0011 18.7 0.1 0.19 11.5 0.0 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_28 PF13521.6 RLN86865.1 - 0.0012 19.1 0.0 0.11 12.8 0.0 3.4 3 0 0 3 3 2 1 AAA domain ATPase_2 PF01637.18 RLN86865.1 - 0.0017 18.3 0.1 0.077 12.9 0.0 3.1 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 RLN86865.1 - 0.0023 18.5 0.0 0.58 10.7 0.0 3.9 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 RLN86865.1 - 0.0087 16.4 0.1 2.8 8.4 0.0 3.5 3 0 0 3 3 3 1 RNA helicase Guanylate_kin PF00625.21 RLN86865.1 - 0.014 15.1 0.1 0.76 9.4 0.0 2.9 2 0 0 2 2 2 0 Guanylate kinase ATP_bind_1 PF03029.17 RLN86865.1 - 0.017 14.9 0.7 0.49 10.1 0.0 3.4 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein Sigma54_activat PF00158.26 RLN86865.1 - 0.033 13.9 0.1 8.6 6.0 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain Rad17 PF03215.15 RLN86865.1 - 0.063 13.2 0.2 0.99 9.3 0.1 3.0 3 0 0 3 3 2 0 Rad17 P-loop domain T2SSE PF00437.20 RLN86865.1 - 0.08 12.0 0.0 2.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.19 RLN86865.1 - 0.098 12.2 0.1 3.4 7.2 0.0 2.8 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.21 RLN86865.1 - 0.11 11.8 0.0 24 4.2 0.0 2.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF3226 PF11536.8 RLN86865.1 - 0.14 11.8 0.1 0.44 10.2 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) DUF87 PF01935.17 RLN86865.1 - 0.18 11.9 0.5 16 5.5 0.0 3.6 3 0 0 3 3 3 0 Helicase HerA, central domain ABC_tran PF00005.27 RLN86865.1 - 0.33 11.5 0.0 0.33 11.5 0.0 4.4 6 0 0 6 6 2 0 ABC transporter Flagellin_N PF00669.20 RLN86865.1 - 2 8.5 7.2 26 4.9 0.2 4.1 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region DUF2524 PF10732.9 RLN86865.1 - 2.4 8.5 7.7 30 5.0 1.6 3.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) Pkinase PF00069.25 RLN86869.1 - 7.9e-06 25.4 0.0 1.1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain F-box-like PF12937.7 RLN86869.1 - 0.00013 21.8 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 F-box-like PPP4R2 PF09184.11 RLN86870.1 - 0.49 9.9 6.2 0.89 9.1 6.2 1.4 1 0 0 1 1 1 0 PPP4R2 Herpes_DNAp_acc PF04929.12 RLN86870.1 - 7.4 5.4 9.6 16 4.3 9.6 1.6 1 0 0 1 1 1 0 Herpes DNA replication accessory factor UPF1_Zn_bind PF09416.10 RLN86871.1 - 1.4e-73 245.9 0.9 1.4e-73 245.9 0.9 2.0 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 RLN86871.1 - 1.4e-59 201.1 0.0 2.4e-59 200.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RLN86871.1 - 2.6e-49 168.4 2.4 2.5e-30 106.1 0.2 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 RLN86871.1 - 5.5e-27 93.9 0.0 1.3e-26 92.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 RLN86871.1 - 1.5e-13 51.0 1.3 8.1e-13 48.5 0.6 2.4 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.6 RLN86871.1 - 5.4e-10 39.8 0.3 1.3e-09 38.5 0.3 1.7 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 RLN86871.1 - 0.00011 21.6 1.2 0.0076 15.5 0.3 3.6 4 1 0 4 4 4 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 RLN86871.1 - 0.00038 20.5 0.0 0.00066 19.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 RLN86871.1 - 0.00069 19.5 0.3 0.002 18.0 0.3 1.9 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 RLN86871.1 - 0.0016 18.0 0.1 0.64 9.5 0.1 2.5 1 1 0 2 2 2 2 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 RLN86871.1 - 0.0054 15.9 0.1 2.3 7.3 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_25 PF13481.6 RLN86871.1 - 0.0082 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 RLN86871.1 - 0.049 13.1 0.1 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 RLN86871.1 - 0.062 12.6 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA PF00004.29 RLN86871.1 - 0.082 13.3 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN86871.1 - 0.11 12.8 0.1 0.27 11.6 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain HCMV_UL139 PF12507.8 RLN86871.1 - 0.13 12.6 0.3 0.28 11.5 0.3 1.4 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein Ribosomal_S13_N PF08069.12 RLN86871.1 - 0.13 12.3 0.1 0.53 10.4 0.0 2.0 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain MULE PF10551.9 RLN86872.1 - 2.8e-12 46.9 0.1 7.3e-12 45.6 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain Bromodomain PF00439.25 RLN86873.1 - 2e-15 56.6 0.0 5.3e-15 55.3 0.0 1.8 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 RLN86873.1 - 2.6e-11 43.2 4.4 4.3e-11 42.5 4.4 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 RLN86873.1 - 0.0046 16.9 1.3 0.012 15.5 1.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-HC5HC2H_2 PF13832.6 RLN86873.1 - 0.045 13.9 0.1 0.088 13.0 0.1 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain Zn_ribbon_SprT PF17283.2 RLN86873.1 - 0.056 13.4 0.3 5.5 7.0 0.0 2.7 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-rbx1 PF12678.7 RLN86873.1 - 0.11 12.8 2.9 0.23 11.8 2.9 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain C1_2 PF03107.16 RLN86873.1 - 0.25 11.7 2.1 0.53 10.6 2.1 1.5 1 0 0 1 1 1 0 C1 domain PHD_2 PF13831.6 RLN86873.1 - 2.7 7.6 6.7 0.13 11.9 0.5 2.0 2 0 0 2 2 2 0 PHD-finger TTL PF03133.15 RLN86874.1 - 1.4e-73 247.6 0.0 2.4e-57 194.3 0.0 2.2 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RLN86874.1 - 2.4e-06 27.0 0.1 0.00041 19.7 0.0 3.1 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RLN86874.1 - 0.0004 19.7 0.0 0.021 14.1 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp Striatin PF08232.12 RLN86874.1 - 2.1 9.0 4.7 11 6.5 2.4 2.4 2 0 0 2 2 2 0 Striatin family TIM PF00121.18 RLN86875.1 - 3.4e-44 151.0 0.1 3.8e-44 150.9 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Cullin PF00888.22 RLN86876.1 - 3e-75 254.1 1.8 4.1e-75 253.6 1.8 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 RLN86876.1 - 6.4e-18 64.6 1.5 6.4e-18 64.6 1.5 2.0 2 0 0 2 2 2 1 Cullin protein neddylation domain Helicase_C PF00271.31 RLN86877.1 - 5.7e-07 29.9 0.1 1.4e-06 28.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GLTP PF08718.11 RLN86877.1 - 0.041 14.2 0.5 0.15 12.3 0.1 2.0 2 0 0 2 2 2 0 Glycolipid transfer protein (GLTP) AKAP7_NLS PF10469.9 RLN86877.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 AKAP7 2'5' RNA ligase-like domain ADK PF00406.22 RLN86878.1 - 8.5e-28 97.4 0.0 2e-13 50.7 0.0 2.1 1 1 1 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 RLN86878.1 - 2.1e-13 50.8 0.1 1.6e-11 44.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RLN86878.1 - 0.022 15.3 0.0 0.032 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RLN86878.1 - 0.044 13.9 0.0 0.053 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RLN86878.1 - 0.1 12.8 0.0 0.14 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 RLN86878.1 - 0.12 11.8 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DAGAT PF03982.13 RLN86879.1 - 3.4e-42 144.4 0.0 1.4e-39 135.8 0.0 2.0 1 1 0 1 1 1 1 Diacylglycerol acyltransferase p450 PF00067.22 RLN86880.1 - 4.4e-69 233.4 0.0 1.5e-62 211.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF4449 PF14613.6 RLN86880.1 - 0.049 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) DUF695 PF05117.12 RLN86880.1 - 0.053 13.7 0.1 9.3 6.4 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF695) p450 PF00067.22 RLN86881.1 - 1.1e-79 268.4 0.0 1.3e-79 268.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 RLN86882.1 - 9.9e-67 225.7 0.0 1.2e-66 225.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 RLN86883.1 - 5.5e-72 243.0 0.1 6.9e-72 242.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 LBR_tudor PF09465.10 RLN86886.1 - 0.0038 17.0 1.5 0.0095 15.7 0.1 2.2 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain DIE2_ALG10 PF04922.12 RLN86887.1 - 1.7e-57 195.5 5.9 2.1e-30 106.3 3.1 2.0 2 0 0 2 2 2 2 DIE2/ALG10 family HSP70 PF00012.20 RLN86888.1 - 5.7e-66 222.9 0.0 1.2e-65 221.9 0.0 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN86888.1 - 0.0041 16.0 1.3 0.011 14.5 0.6 1.9 2 0 0 2 2 2 1 MreB/Mbl protein BcrAD_BadFG PF01869.20 RLN86888.1 - 0.06 12.8 1.4 7.9 5.9 0.0 2.8 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Kinesin PF00225.23 RLN86889.1 - 5.2e-104 347.8 0.1 2.3e-103 345.6 0.0 2.3 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RLN86889.1 - 8.1e-18 64.8 0.0 2.8e-17 63.0 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding ABC_membrane PF00664.23 RLN86890.1 - 5.3e-100 334.6 31.0 6.3e-54 183.5 4.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN86890.1 - 8.6e-71 236.8 0.0 1.8e-34 119.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN86890.1 - 1e-10 41.4 3.6 0.004 16.6 0.0 4.2 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RLN86890.1 - 1.4e-08 34.3 0.5 0.0062 16.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 RLN86890.1 - 1.6e-07 30.8 0.0 0.017 14.4 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.6 RLN86890.1 - 2.6e-06 27.9 5.8 0.0074 16.7 0.3 3.0 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 RLN86890.1 - 3e-06 27.5 1.6 0.067 13.5 0.1 3.5 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 RLN86890.1 - 3.2e-06 26.2 1.5 0.014 14.2 0.2 2.7 2 0 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 RLN86890.1 - 5.1e-06 26.5 0.0 0.069 13.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 RLN86890.1 - 8.8e-06 25.6 2.4 0.11 12.2 0.3 3.6 2 2 0 2 2 2 2 AAA domain APS_kinase PF01583.20 RLN86890.1 - 2e-05 24.5 0.1 0.15 12.0 0.0 2.4 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_21 PF13304.6 RLN86890.1 - 3e-05 24.0 6.6 0.63 9.8 0.0 4.1 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 RLN86890.1 - 4e-05 23.3 0.0 0.23 11.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 RLN86890.1 - 4.2e-05 23.4 0.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 RLN86890.1 - 0.00047 20.3 1.5 0.17 12.0 0.1 2.7 2 1 0 2 2 2 1 Helicase HerA, central domain AAA_5 PF07728.14 RLN86890.1 - 0.00049 20.1 0.6 0.61 10.1 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 RLN86890.1 - 0.00056 20.5 0.0 0.78 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 RLN86890.1 - 0.0007 19.9 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 RLN86890.1 - 0.00071 19.8 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain G-alpha PF00503.20 RLN86890.1 - 0.00079 18.7 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 RLN86890.1 - 0.0013 18.3 0.0 0.9 9.0 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 RLN86890.1 - 0.0016 18.2 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RLN86890.1 - 0.0026 18.2 6.1 0.14 12.6 0.1 4.1 3 2 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 RLN86890.1 - 0.0041 16.9 0.4 5.6 6.7 0.2 3.7 3 1 0 3 3 3 0 DEAD/DEAH box helicase SRP54 PF00448.22 RLN86890.1 - 0.005 16.5 0.0 0.59 9.7 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 RLN86890.1 - 0.008 15.6 0.0 0.53 9.6 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.6 RLN86890.1 - 0.013 15.7 6.3 3.2 8.1 0.5 3.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 RLN86890.1 - 0.018 15.1 0.1 9.2 6.4 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 RLN86890.1 - 0.022 15.2 0.5 3.2 8.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RLN86890.1 - 0.053 13.4 0.0 15 5.5 0.0 2.7 2 0 0 2 2 2 0 NACHT domain DUF3621 PF12285.8 RLN86890.1 - 0.063 13.6 0.6 0.12 12.7 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3621) Rad17 PF03215.15 RLN86890.1 - 0.082 12.8 0.2 14 5.6 0.0 3.1 4 0 0 4 4 3 0 Rad17 P-loop domain ATP-synt_ab PF00006.25 RLN86890.1 - 0.086 12.5 0.0 7 6.2 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.6 RLN86890.1 - 0.096 13.1 0.3 28 5.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain Ploopntkinase3 PF18751.1 RLN86890.1 - 0.1 12.5 0.1 16 5.3 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ATP_bind_1 PF03029.17 RLN86890.1 - 0.11 12.3 0.1 5.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 RLN86890.1 - 0.2 11.4 4.2 9.2 6.0 0.0 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein PAP2 PF01569.21 RLN86890.1 - 0.22 11.3 3.9 0.81 9.5 0.1 2.9 2 0 0 2 2 2 0 PAP2 superfamily AA_permease_2 PF13520.6 RLN86891.1 - 3.1e-36 125.1 45.4 4.3e-36 124.7 45.4 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN86891.1 - 5e-22 78.1 47.0 1.5e-21 76.5 47.0 1.8 1 1 0 1 1 1 1 Amino acid permease CD34_antigen PF06365.12 RLN86891.1 - 0.037 13.6 0.2 0.12 11.9 0.2 1.9 1 0 0 1 1 1 0 CD34/Podocalyxin family Phage_holin_3_6 PF07332.11 RLN86891.1 - 0.26 11.3 0.1 0.26 11.3 0.1 5.4 3 2 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III ADH_N PF08240.12 RLN86892.1 - 7.1e-23 80.6 3.4 7.1e-23 80.6 3.4 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN86892.1 - 6.2e-16 58.6 0.0 1e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN86892.1 - 0.00036 20.0 0.0 0.00055 19.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN86892.1 - 0.0013 18.0 0.1 0.0023 17.3 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 RLN86892.1 - 0.014 16.4 0.0 0.022 15.8 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Cu_amine_oxid PF01179.20 RLN86893.1 - 7.8e-151 502.6 0.0 9.5e-151 502.3 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 RLN86893.1 - 3.2e-15 56.4 0.0 2.1e-14 53.7 0.0 2.3 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 RLN86893.1 - 8.4e-10 38.8 0.0 2.1e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain p450 PF00067.22 RLN86894.1 - 4.5e-74 249.9 0.0 5.7e-74 249.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 RLN86896.1 - 5.1e-21 74.6 4.3 4.5e-06 27.3 0.1 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN86896.1 - 7.9e-13 48.5 0.1 0.012 15.9 0.0 4.9 4 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain GAS PF13851.6 RLN86896.1 - 0.002 17.5 5.3 0.002 17.5 5.3 3.6 3 1 1 4 4 4 2 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 RLN86896.1 - 0.0052 16.6 8.4 0.0052 16.6 8.4 3.3 2 1 1 3 3 3 1 Coiled-coil region of CCDC155 or KASH UPF0242 PF06785.11 RLN86896.1 - 0.0057 16.8 10.0 0.0057 16.8 10.0 3.7 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus Nup160 PF11715.8 RLN86896.1 - 0.011 14.4 0.0 0.55 8.8 0.0 2.8 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Rotamase_2 PF13145.6 RLN86896.1 - 8.3 7.3 9.9 3.9 8.3 2.6 3.5 3 0 0 3 3 3 0 PPIC-type PPIASE domain HAGH_C PF16123.5 RLN86897.1 - 3.3e-25 88.4 0.1 6.3e-25 87.5 0.1 1.5 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 RLN86897.1 - 3.5e-11 43.5 5.2 3.7e-11 43.4 3.9 1.7 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 RLN86897.1 - 0.00045 19.8 0.5 0.0011 18.6 0.3 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 RLN86897.1 - 0.0016 18.4 0.1 0.003 17.4 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MalM PF07148.12 RLN86897.1 - 0.084 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Maltose operon periplasmic protein precursor (MalM) Ank_2 PF12796.7 RLN86898.1 - 9.1e-31 106.3 2.2 1.6e-15 57.4 0.5 5.1 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN86898.1 - 6.2e-21 74.2 7.6 7.5e-06 26.1 0.5 7.4 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN86898.1 - 1.7e-17 61.7 8.0 0.0043 17.4 0.1 8.4 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 RLN86898.1 - 1.2e-16 60.3 12.1 4.7e-06 26.8 0.2 7.3 7 1 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 RLN86898.1 - 1.9e-13 50.6 4.9 2e-07 31.4 0.0 5.6 3 1 2 5 5 5 2 Ankyrin repeats (many copies) NAD_synthase PF02540.17 RLN86900.1 - 1.7e-07 30.6 0.0 0.00018 20.7 0.0 2.1 2 0 0 2 2 2 2 NAD synthase tRNA_Me_trans PF03054.16 RLN86900.1 - 1.8e-06 27.0 0.1 0.0017 17.2 0.1 2.2 2 0 0 2 2 2 2 tRNA methyl transferase QueC PF06508.13 RLN86900.1 - 0.00025 20.6 0.5 0.38 10.2 0.1 2.6 2 1 1 3 3 3 2 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 RLN86900.1 - 0.00033 20.4 0.0 0.00046 20.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 RLN86900.1 - 0.17 11.6 0.3 0.6 9.8 0.3 2.0 1 1 0 1 1 1 0 PP-loop family GST_N_3 PF13417.6 RLN86901.1 - 2.2e-10 40.8 0.0 5.1e-09 36.4 0.0 2.6 2 1 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RLN86901.1 - 1.2e-09 38.3 0.0 2.4e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN86901.1 - 7.4e-07 29.4 0.0 7.1e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RLN86901.1 - 2e-06 27.9 0.0 3.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RLN86901.1 - 0.00013 22.1 0.1 0.00036 20.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RLN86901.1 - 0.074 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Esterase_phd PF10503.9 RLN86901.1 - 0.077 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase LSDAT_euk PF18139.1 RLN86901.1 - 0.079 12.3 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 SLOG in TRPM 2Fe-2S_thioredx PF01257.19 RLN86902.1 - 0.2 11.5 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Ank_2 PF12796.7 RLN86903.1 - 3e-22 79.0 6.6 9e-09 35.8 0.2 4.5 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN86903.1 - 2.4e-21 75.8 7.9 1e-05 26.0 0.1 8.0 4 4 4 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN86903.1 - 7.6e-18 64.3 10.5 0.011 16.1 0.0 8.7 5 2 4 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN86903.1 - 5.1e-14 51.0 0.3 4.1 8.3 0.0 9.3 10 0 0 10 10 10 2 Ankyrin repeat Ank PF00023.30 RLN86903.1 - 0.011 16.2 1.9 37 5.0 0.0 5.5 5 2 2 7 7 7 0 Ankyrin repeat DUF1843 PF08898.10 RLN86903.1 - 0.017 15.6 3.5 18 5.9 0.0 5.3 6 0 0 6 6 6 0 Domain of unknown function (DUF1843) DUF1979 PF09322.10 RLN86903.1 - 0.065 13.1 0.1 1.6 8.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1979) DUF3322 PF11795.8 RLN86903.1 - 0.09 12.8 0.5 0.71 9.9 0.0 2.8 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) tRNA-synt_2 PF00152.20 RLN86904.1 - 2.3e-42 145.2 1.3 2.9e-42 144.8 1.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RLN86904.1 - 1.5e-13 50.5 0.3 3.3e-13 49.4 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 RLN86904.1 - 0.00052 19.6 0.1 0.0009 18.8 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Nucleopor_Nup85 PF07575.13 RLN86906.1 - 8.9e-66 222.6 6.6 1.4e-65 222.0 6.6 1.2 1 0 0 1 1 1 1 Nup85 Nucleoporin DUF2802 PF10975.8 RLN86906.1 - 0.49 10.5 3.4 7.2 6.8 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) Mito_fiss_Elm1 PF06258.11 RLN86907.1 - 6.4e-68 229.2 0.2 8e-68 228.8 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial fission ELM1 BLOC1_2 PF10046.9 RLN86908.1 - 0.014 15.6 2.7 0.029 14.6 2.7 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.11 RLN86908.1 - 0.035 14.3 6.7 0.059 13.6 6.7 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Snapin_Pallidin PF14712.6 RLN86908.1 - 0.29 11.6 7.6 0.68 10.4 7.6 1.6 1 0 0 1 1 1 0 Snapin/Pallidin Spc24 PF08286.11 RLN86908.1 - 0.59 10.4 3.2 1.5 9.1 3.2 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 SR-25 PF10500.9 RLN86908.1 - 2.5 7.6 10.0 6.9 6.2 1.0 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DivIC PF04977.15 RLN86908.1 - 3.3 7.5 8.0 0.69 9.7 3.8 2.1 2 0 0 2 2 2 0 Septum formation initiator ARL2_Bind_BART PF11527.8 RLN86909.1 - 7.3e-05 22.9 0.0 7.9e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Tachykinin PF02202.16 RLN86909.1 - 0.14 12.1 0.4 1.3 9.1 0.1 2.2 2 0 0 2 2 2 0 Tachykinin family eIF-5_eIF-2B PF01873.17 RLN86910.1 - 1.9e-35 121.3 0.1 5.6e-35 119.8 0.1 1.9 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 RLN86910.1 - 1.7e-17 63.3 2.8 1.7e-17 63.3 2.8 3.0 2 1 0 2 2 1 1 eIF4-gamma/eIF5/eIF2-epsilon Zip PF02535.22 RLN86910.1 - 0.013 14.7 8.9 0.017 14.4 8.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIF_alpha PF05793.12 RLN86910.1 - 0.035 12.7 30.4 0.054 12.1 30.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DDHD PF02862.17 RLN86910.1 - 0.049 13.8 3.2 0.082 13.1 3.2 1.5 1 0 0 1 1 1 0 DDHD domain Apt1 PF10351.9 RLN86910.1 - 0.11 11.4 13.3 0.14 11.0 13.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain NPR3 PF03666.13 RLN86910.1 - 0.18 10.6 18.4 0.25 10.1 18.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Gti1_Pac2 PF09729.9 RLN86910.1 - 0.39 10.8 11.8 0.68 10.0 11.8 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family AAA_11 PF13086.6 RLN86910.1 - 0.5 10.1 11.7 0.74 9.6 11.7 1.3 1 0 0 1 1 1 0 AAA domain 2-Hacid_dh PF00389.30 RLN86910.1 - 0.53 9.9 3.5 16 5.2 1.4 2.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain FancD2 PF14631.6 RLN86910.1 - 1.1 6.5 12.0 1.3 6.3 12.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Presenilin PF01080.17 RLN86910.1 - 1.3 7.7 15.6 1.8 7.2 15.6 1.2 1 0 0 1 1 1 0 Presenilin DDRGK PF09756.9 RLN86910.1 - 1.7 8.2 30.9 3.3 7.3 30.9 1.4 1 0 0 1 1 1 0 DDRGK domain DUF4775 PF16001.5 RLN86910.1 - 1.9 7.8 37.3 2.9 7.2 37.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) Tim54 PF11711.8 RLN86910.1 - 2.2 6.9 17.4 3.4 6.4 17.4 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Vfa1 PF08432.10 RLN86910.1 - 3.6 7.9 30.6 6.9 7.0 30.6 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SLC12 PF03522.15 RLN86910.1 - 4.1 6.3 15.8 5.7 5.9 15.8 1.2 1 0 0 1 1 1 0 Solute carrier family 12 ALMT PF11744.8 RLN86910.1 - 5 5.8 13.4 7.1 5.3 13.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Peptidase_S64 PF08192.11 RLN86910.1 - 5.2 5.4 11.8 6.9 5.0 11.8 1.2 1 0 0 1 1 1 0 Peptidase family S64 CDC45 PF02724.14 RLN86910.1 - 5.6 5.1 21.6 7.9 4.6 21.6 1.2 1 0 0 1 1 1 0 CDC45-like protein MMM1 PF10296.9 RLN86910.1 - 5.7 5.9 10.3 8.7 5.3 10.3 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 PTPRCAP PF15713.5 RLN86910.1 - 7.7 6.8 26.3 0.52 10.6 19.7 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Aldedh PF00171.22 RLN86911.1 - 2.9e-186 619.5 0.1 3.3e-186 619.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family IPI_T4 PF11634.8 RLN86911.1 - 0.031 14.3 0.1 5.7 7.0 0.0 2.9 3 0 0 3 3 3 0 Nuclease inhibitor from bacteriophage T4 NTP_transf_4 PF13562.6 RLN86911.1 - 0.034 14.4 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 Sugar nucleotidyl transferase Stm1_N PF09598.10 RLN86912.1 - 0.001 19.9 1.5 0.001 19.9 1.5 4.5 4 2 0 4 4 4 1 Stm1 MULE PF10551.9 RLN86913.1 - 6.1e-12 45.8 0.0 2.1e-11 44.1 0.0 1.9 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 RLN86913.1 - 1.1e-05 25.0 0.1 2.8e-05 23.7 0.1 1.7 1 0 0 1 1 1 1 SWIM zinc finger Transposase_mut PF00872.18 RLN86913.1 - 0.0038 16.1 0.1 0.0059 15.5 0.1 1.2 1 0 0 1 1 1 1 Transposase, Mutator family Ras PF00071.22 RLN86914.1 - 7.2e-21 74.5 1.0 1.3e-13 50.9 0.7 2.1 1 1 1 2 2 2 2 Ras family Roc PF08477.13 RLN86914.1 - 1.6e-13 50.9 0.0 5.2e-06 26.7 0.0 2.3 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 RLN86914.1 - 0.011 15.8 0.1 0.016 15.2 0.1 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain TniB PF05621.11 RLN86914.1 - 0.017 14.5 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 RLN86914.1 - 0.02 14.8 0.0 0.81 9.6 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Arf PF00025.21 RLN86914.1 - 0.021 14.3 0.1 1.5 8.2 0.0 2.1 1 1 1 2 2 2 0 ADP-ribosylation factor family MCM PF00493.23 RLN86914.1 - 0.023 13.8 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain AAA_16 PF13191.6 RLN86914.1 - 0.031 14.7 0.0 0.054 13.9 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 RLN86914.1 - 0.047 13.8 0.0 0.15 12.1 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.20 RLN86914.1 - 0.082 12.0 0.0 0.32 10.1 0.0 1.7 1 1 1 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.6 RLN86914.1 - 0.15 12.3 0.0 0.39 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain EF-hand_7 PF13499.6 RLN86915.1 - 6.7e-09 36.1 3.6 0.019 15.4 0.0 3.9 3 0 0 3 3 3 3 EF-hand domain pair zf-RanBP PF00641.18 RLN86915.1 - 0.00013 21.2 20.5 0.00022 20.5 6.1 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others EF-hand_6 PF13405.6 RLN86915.1 - 0.017 15.0 0.6 72 3.7 0.0 4.6 5 0 0 5 5 5 0 EF-hand domain DZR PF12773.7 RLN86915.1 - 0.49 10.5 8.3 6.1 7.0 0.8 2.5 2 0 0 2 2 2 0 Double zinc ribbon Skp1 PF01466.19 RLN86916.1 - 1.4e-27 95.5 0.5 1.4e-27 95.5 0.5 1.7 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 RLN86916.1 - 3.9e-19 68.6 1.0 4.3e-18 65.2 1.0 2.3 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 RLN86916.1 - 0.003 17.8 0.0 0.02 15.1 0.0 2.0 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 RLN86917.1 - 5.4e-13 49.2 0.1 3.3e-11 43.4 0.0 2.1 1 1 1 2 2 2 2 BTB/POZ domain Repressor_Mnt PF11423.8 RLN86917.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Regulatory protein Mnt AAA PF00004.29 RLN86918.1 - 2.6e-17 63.5 0.3 6.6e-17 62.2 0.1 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 RLN86918.1 - 0.00015 21.7 1.2 0.1 12.6 0.1 3.5 3 1 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 RLN86918.1 - 0.13 12.3 0.3 0.56 10.2 0.1 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ACC_epsilon PF13822.6 RLN86919.1 - 0.016 15.9 1.4 0.016 15.9 1.4 3.9 5 0 0 5 5 5 0 Acyl-CoA carboxylase epsilon subunit Conotoxin PF02950.17 RLN86919.1 - 0.14 13.2 0.2 0.62 11.1 0.0 2.1 2 0 0 2 2 2 0 Conotoxin EF-hand_8 PF13833.6 RLN86920.1 - 1e-08 34.9 2.5 0.00017 21.4 0.3 4.5 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 RLN86920.1 - 1.3e-07 31.0 3.9 0.00023 20.8 0.1 4.9 5 0 0 5 5 5 1 EF-hand domain EF-hand_1 PF00036.32 RLN86920.1 - 1.8e-07 30.2 5.5 8.9e-06 24.9 0.3 4.3 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.6 RLN86920.1 - 3.2e-07 30.7 0.0 0.0061 17.0 0.1 4.5 4 1 1 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN86920.1 - 0.00032 20.0 2.9 0.0029 17.0 0.1 3.1 3 0 0 3 3 3 1 EF hand SCNM1_acidic PF15805.5 RLN86923.1 - 2.7 7.8 4.8 5.7 6.8 4.8 1.5 1 0 0 1 1 1 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 DDE_1 PF03184.19 RLN86924.1 - 1.8e-07 31.0 0.0 2.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease COMM_domain PF07258.14 RLN86926.1 - 4.7e-07 29.8 0.0 6.9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 COMM domain DUF4089 PF13318.6 RLN86926.1 - 0.055 13.9 0.3 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4089) ABC_tran PF00005.27 RLN86927.1 - 3e-38 131.5 0.0 1.3e-18 67.8 0.0 2.6 3 0 0 3 3 2 2 ABC transporter Ribosomal_L24e PF01246.20 RLN86927.1 - 2.5e-31 107.7 5.6 5.7e-31 106.6 5.6 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e RLI PF04068.15 RLN86927.1 - 2.3e-13 49.7 5.4 6.4e-13 48.3 5.4 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 RLN86927.1 - 1.1e-10 41.3 4.8 0.00039 19.9 1.7 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RLN86927.1 - 2.4e-09 37.4 6.4 0.15 11.8 0.0 4.4 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 RLN86927.1 - 2.8e-07 30.1 2.9 2.8e-07 30.1 2.9 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_16 PF13191.6 RLN86927.1 - 5.9e-07 30.0 0.3 0.031 14.7 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 RLN86927.1 - 7.6e-06 26.6 1.4 0.1 13.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain Fer4_6 PF12837.7 RLN86927.1 - 1.9e-05 24.5 2.4 1.9e-05 24.5 2.4 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.6 RLN86927.1 - 2.4e-05 24.2 4.0 0.085 12.6 0.0 3.8 4 0 0 4 4 4 2 AAA ATPase domain AAA PF00004.29 RLN86927.1 - 2.5e-05 24.7 0.0 0.18 12.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN86927.1 - 6.4e-05 23.3 0.2 0.095 13.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 RLN86927.1 - 9.4e-05 22.4 0.1 0.19 11.6 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 RLN86927.1 - 0.00015 21.4 0.1 0.51 10.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 RLN86927.1 - 0.00022 21.2 1.7 0.082 12.8 0.0 3.0 3 0 0 3 3 3 1 NACHT domain SRP54 PF00448.22 RLN86927.1 - 0.00031 20.4 1.5 0.073 12.7 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_2 PF12797.7 RLN86927.1 - 0.00095 19.1 0.8 0.00095 19.1 0.8 2.8 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_33 PF13671.6 RLN86927.1 - 0.001 19.3 1.0 1.9 8.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 RLN86927.1 - 0.0011 19.0 0.3 0.18 11.8 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) Fer4_21 PF14697.6 RLN86927.1 - 0.0011 19.0 11.9 0.0032 17.6 11.9 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Rad17 PF03215.15 RLN86927.1 - 0.0019 18.2 0.2 0.53 10.2 0.0 2.7 3 0 0 3 3 2 1 Rad17 P-loop domain TsaE PF02367.17 RLN86927.1 - 0.0022 18.0 0.6 0.14 12.1 0.1 2.9 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_7 PF12838.7 RLN86927.1 - 0.0023 18.5 0.7 0.0023 18.5 0.7 3.0 3 0 0 3 3 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 RLN86927.1 - 0.0037 17.3 1.4 0.0037 17.3 1.4 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Thymidylate_kin PF02223.17 RLN86927.1 - 0.0038 16.9 0.0 3.5 7.3 0.0 2.9 2 0 0 2 2 2 1 Thymidylate kinase RNA_helicase PF00910.22 RLN86927.1 - 0.0062 16.9 0.0 4.7 7.7 0.0 3.1 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 RLN86927.1 - 0.0078 16.0 0.3 0.79 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RLN86927.1 - 0.0086 15.8 0.2 0.71 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_16 PF13484.6 RLN86927.1 - 0.0097 16.8 0.2 0.0097 16.8 0.2 3.4 4 0 0 4 4 2 1 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 RLN86927.1 - 0.012 15.8 11.4 0.012 15.8 11.4 2.4 2 1 0 2 2 2 0 4Fe-4S dicluster domain NTPase_1 PF03266.15 RLN86927.1 - 0.016 15.1 0.2 1 9.2 0.0 3.0 3 0 0 3 3 2 0 NTPase MobB PF03205.14 RLN86927.1 - 0.016 15.1 0.3 0.19 11.6 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 RLN86927.1 - 0.039 14.5 0.0 8.1 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RLN86927.1 - 0.044 14.0 0.1 13 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 RLN86927.1 - 0.065 13.0 0.0 15 5.2 0.0 2.5 2 0 0 2 2 2 0 Virulence-associated protein E NB-ARC PF00931.22 RLN86927.1 - 0.09 11.9 0.0 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.23 RLN86927.1 - 0.09 12.9 0.6 16 5.6 0.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_7 PF12775.7 RLN86927.1 - 0.14 11.6 0.0 2.8 7.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Fer4_8 PF13183.6 RLN86927.1 - 0.29 11.6 9.9 0.22 12.0 0.2 3.4 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 RLN86927.1 - 6.2 7.5 14.2 0.12 13.0 1.1 3.4 2 1 1 3 3 3 0 4Fe-4S dicluster domain Myosin_head PF00063.21 RLN86928.1 - 1.4e-80 271.4 0.0 3.7e-70 237.0 0.0 3.6 2 1 0 2 2 2 2 Myosin head (motor domain) PH PF00169.29 RLN86928.1 - 2.1e-06 28.2 0.0 7e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN86928.1 - 0.00027 21.3 0.5 0.15 12.5 0.0 3.0 2 0 0 2 2 2 1 Pleckstrin homology domain AAA_22 PF13401.6 RLN86928.1 - 0.0015 18.8 3.1 0.01 16.1 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 RLN86928.1 - 0.0034 17.8 1.2 0.046 14.1 0.0 3.1 2 0 0 2 2 2 1 AAA ATPase domain Glutaredoxin PF00462.24 RLN86928.1 - 0.0061 16.8 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin AAA_5 PF07728.14 RLN86928.1 - 0.096 12.7 0.0 0.39 10.7 0.0 2.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 RLN86928.1 - 0.11 12.2 0.1 1.4 8.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain PAPA-1 PF04795.12 RLN86928.1 - 0.45 11.3 3.0 0.7 10.7 1.0 2.5 2 0 0 2 2 2 0 PAPA-1-like conserved region Hexapep PF00132.24 RLN86929.1 - 1.8e-16 59.1 18.2 6e-06 25.8 3.8 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 RLN86929.1 - 7e-06 25.7 13.7 0.0048 16.6 4.0 4.1 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Med25_SD1 PF11235.8 RLN86929.1 - 0.13 12.6 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 MatE PF01554.18 RLN86932.1 - 2.1e-55 186.7 28.2 7.9e-30 103.6 2.0 3.0 3 1 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 RLN86932.1 - 2.5 8.1 38.8 0.17 12.0 14.6 4.2 2 1 3 5 5 5 0 Polysaccharide biosynthesis C-terminal domain Mito_carr PF00153.27 RLN86933.1 - 5.2e-61 202.6 6.6 7e-20 70.8 0.0 3.8 4 0 0 4 4 4 3 Mitochondrial carrier protein CMS1 PF14617.6 RLN86934.1 - 2.4e-27 95.9 0.0 2.8e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 RLN86934.1 - 5.9e-06 26.2 0.0 8.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Abhydrolase_1 PF00561.20 RLN86935.1 - 1.1e-09 38.4 0.0 2.6e-08 33.8 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN86935.1 - 1.5e-06 27.7 0.0 4.9e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN86935.1 - 0.0058 17.3 0.0 0.014 16.0 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 RLN86935.1 - 0.0065 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Aldedh PF00171.22 RLN86936.1 - 5.1e-108 361.6 0.1 1.1e-60 205.5 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Albumin_I PF08027.11 RLN86936.1 - 0.38 10.4 1.7 8.2 6.1 0.0 2.7 2 0 0 2 2 2 0 Albumin I chain b DUF1180 PF06679.12 RLN86938.1 - 5.9 7.3 9.3 3.6 8.0 2.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1180) Abhydrolase_1 PF00561.20 RLN86939.1 - 0.031 13.9 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ribosomal_L11 PF00298.19 RLN86940.1 - 9.1e-28 96.6 0.2 1.8e-27 95.7 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 RLN86940.1 - 2e-25 88.4 0.7 1.7e-24 85.4 0.1 2.3 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Scs3p PF10261.9 RLN86940.1 - 3.5e-05 23.4 0.3 6.3e-05 22.6 0.3 1.4 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Actin PF00022.19 RLN86941.1 - 2.6e-144 480.8 0.0 8.9e-144 479.1 0.0 1.7 1 1 0 1 1 1 1 Actin Sugar_tr PF00083.24 RLN86942.1 - 1.5e-26 93.3 29.4 5.2e-24 84.9 10.1 2.6 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 RLN86942.1 - 2.9e-22 79.1 49.5 5e-20 71.7 12.5 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Abhydrolase_1 PF00561.20 RLN86944.1 - 7.3e-09 35.6 0.0 3.8e-07 30.0 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN86944.1 - 2.3e-06 27.0 0.0 6e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN86944.1 - 8.4e-05 23.3 0.0 0.00025 21.7 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 RLN86944.1 - 0.00061 19.2 0.0 0.00098 18.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Iso_dh PF00180.20 RLN86945.1 - 2.1e-114 382.3 0.0 1e-69 235.4 0.0 2.0 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase ASFV_J13L PF05568.11 RLN86946.1 - 1.1 8.9 29.2 1.2 8.8 9.7 2.3 2 0 0 2 2 2 0 African swine fever virus J13L protein DUF2486 PF10667.9 RLN86946.1 - 5.2 7.2 42.7 1.4 9.1 16.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) DUF5585 PF17823.1 RLN86947.1 - 0.09 11.7 20.7 0.13 11.2 20.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5585) PRCC PF10253.9 RLN86947.1 - 3.5 8.3 10.1 5 7.8 10.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting ASFV_J13L PF05568.11 RLN86947.1 - 8.3 6.1 19.2 5.9 6.6 6.6 2.3 1 1 1 2 2 2 0 African swine fever virus J13L protein Pkinase_Tyr PF07714.17 RLN86948.1 - 1e-43 149.5 0.0 1.5e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN86948.1 - 4.7e-37 127.8 0.0 7.8e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ABC1 PF03109.16 RLN86948.1 - 0.0067 16.6 0.0 0.025 14.7 0.0 1.9 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 RLN86948.1 - 0.088 12.7 0.1 0.088 12.7 0.1 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family DZR PF12773.7 RLN86948.1 - 0.13 12.3 1.0 0.29 11.2 1.0 1.5 1 0 0 1 1 1 0 Double zinc ribbon DUF1272 PF06906.11 RLN86948.1 - 0.14 12.3 1.1 4.5 7.4 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Pkinase_Tyr PF07714.17 RLN86949.1 - 1e-38 133.1 0.0 8.9e-38 130.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RLN86949.1 - 7.3e-30 104.2 0.0 3.6e-29 101.9 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain DZR PF12773.7 RLN86949.1 - 0.0013 18.7 1.3 0.003 17.5 1.3 1.5 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 RLN86949.1 - 0.0029 18.3 1.9 0.0066 17.2 1.9 1.6 1 0 0 1 1 1 1 zinc-ribbon family UPF0547 PF10571.9 RLN86949.1 - 0.0074 16.4 9.5 0.014 15.4 9.5 1.5 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 Mitofilin PF09731.9 RLN86949.1 - 0.043 12.7 9.2 0.066 12.0 9.2 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein zinc_ribbon_2 PF13240.6 RLN86949.1 - 0.91 9.3 9.1 2.7 7.8 9.1 1.9 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 RLN86949.1 - 1.6 8.9 8.1 2.3 8.4 0.3 3.4 3 0 0 3 3 3 0 Zinc ribbon domain A2L_zn_ribbon PF08792.10 RLN86949.1 - 4.2 7.2 5.8 1.4 8.7 0.1 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain Pkinase_Tyr PF07714.17 RLN86950.1 - 3.8e-28 98.5 0.0 6.9e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN86950.1 - 6.2e-21 74.9 0.0 1.1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 RLN86950.1 - 0.013 14.9 0.2 0.024 14.0 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sugar_tr PF00083.24 RLN86951.1 - 2.4e-06 26.7 1.0 2.4e-06 26.7 1.0 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter DUF4750 PF15938.5 RLN86952.1 - 0.31 10.7 2.5 0.57 9.9 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4750) CTD_bind PF04818.13 RLN86952.1 - 0.33 11.8 2.0 1.3 9.9 2.0 2.2 1 1 0 1 1 1 0 RNA polymerase II-binding domain. Nbl1_Borealin_N PF10444.9 RLN86952.1 - 2.1 8.0 5.9 1.4 8.6 0.3 2.3 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal Nramp PF01566.18 RLN86953.1 - 7.6e-119 396.9 15.1 7.6e-119 396.9 15.1 2.0 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Methyltransf_25 PF13649.6 RLN86954.1 - 1.6e-07 32.0 0.0 2e-05 25.2 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 RLN86954.1 - 0.00013 21.5 0.0 0.00024 20.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 RLN86954.1 - 0.002 18.0 0.0 0.0045 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN86954.1 - 0.0034 18.0 0.0 0.023 15.3 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN86954.1 - 0.08 13.7 0.0 0.21 12.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 RLN86954.1 - 0.086 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 RLN86954.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain ATP-synt_ab PF00006.25 RLN86955.1 - 4e-21 75.7 0.0 6.3e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Nif11 PF07862.11 RLN86955.1 - 0.071 13.4 0.1 0.41 11.0 0.1 2.3 1 0 0 1 1 1 0 Nif11 domain CUE PF02845.16 RLN86957.1 - 2.2e-06 27.2 1.0 3.7e-06 26.5 0.1 1.9 2 0 0 2 2 2 1 CUE domain Peptidase_S8 PF00082.22 RLN86959.1 - 1.3e-79 267.6 2.4 1.8e-79 267.1 2.4 1.2 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 RLN86959.1 - 3.7e-60 202.7 0.0 6.2e-60 201.9 0.0 1.4 1 0 0 1 1 1 1 Tripeptidyl peptidase II PH_2 PF08458.10 RLN86959.1 - 0.018 15.4 0.0 0.038 14.3 0.0 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Pkinase_Tyr PF07714.17 RLN86960.1 - 3.3e-40 138.0 0.0 5.9e-40 137.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN86960.1 - 4.5e-35 121.3 0.0 2.2e-34 119.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain UPF0547 PF10571.9 RLN86960.1 - 8.5e-05 22.5 1.3 0.00026 21.0 1.3 1.9 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 DZR PF12773.7 RLN86960.1 - 0.00038 20.4 0.9 0.00088 19.2 0.9 1.5 1 0 0 1 1 1 1 Double zinc ribbon TetR_C_29 PF17938.1 RLN86960.1 - 0.00064 19.8 0.6 0.0019 18.3 0.6 1.8 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain zinc_ribbon_15 PF17032.5 RLN86960.1 - 0.0007 20.3 0.1 0.0018 19.0 0.1 1.7 1 0 0 1 1 1 1 zinc-ribbon family RIO1 PF01163.22 RLN86960.1 - 0.0018 17.9 0.1 0.088 12.4 0.0 2.6 2 0 0 2 2 2 1 RIO1 family zinc_ribbon_2 PF13240.6 RLN86960.1 - 0.0023 17.6 2.0 0.0023 17.6 2.0 2.0 2 0 0 2 2 2 1 zinc-ribbon domain Kinase-like PF14531.6 RLN86960.1 - 0.0038 16.6 0.0 0.014 14.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 RLN86960.1 - 0.012 15.5 1.3 0.078 12.9 0.0 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family zf-ribbon_3 PF13248.6 RLN86960.1 - 0.036 13.5 2.3 0.089 12.2 2.3 1.7 1 0 0 1 1 1 0 zinc-ribbon domain ABC1 PF03109.16 RLN86960.1 - 0.054 13.6 0.1 0.68 10.1 0.0 2.6 2 1 0 2 2 2 0 ABC1 family PhaC_N PF07167.13 RLN86960.1 - 0.055 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus DUF2116 PF09889.9 RLN86960.1 - 0.09 12.8 0.4 0.09 12.8 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Laminin_I PF06008.14 RLN86960.1 - 0.26 11.0 6.6 0.075 12.7 3.2 1.7 2 0 0 2 2 2 0 Laminin Domain I SAS4 PF15460.6 RLN86960.1 - 3.1 7.9 7.4 3.8 7.7 0.1 2.7 2 1 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 Pkinase_Tyr PF07714.17 RLN86961.1 - 3.4e-39 134.7 0.0 7.7e-39 133.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN86961.1 - 1.5e-32 113.0 0.0 4.2e-32 111.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain UPF0547 PF10571.9 RLN86961.1 - 0.00038 20.5 1.7 0.001 19.1 1.7 1.7 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 DZR PF12773.7 RLN86961.1 - 0.00049 20.1 1.1 0.0014 18.6 1.1 1.8 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 RLN86961.1 - 0.00085 19.0 1.9 0.0022 17.6 1.9 1.8 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 RLN86961.1 - 0.0011 19.6 0.2 0.0036 18.0 0.2 1.9 1 0 0 1 1 1 1 zinc-ribbon family TOPRIM_C PF16898.5 RLN86961.1 - 0.063 13.5 1.3 0.14 12.4 1.3 1.5 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM Zein PF01559.16 RLN86961.1 - 0.072 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Zein seed storage protein zf-ribbon_3 PF13248.6 RLN86961.1 - 0.096 12.1 1.7 0.24 10.8 1.7 1.8 1 0 0 1 1 1 0 zinc-ribbon domain DUF2116 PF09889.9 RLN86961.1 - 0.25 11.4 3.4 0.22 11.5 0.8 2.3 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Antimicrobial24 PF16049.5 RLN86961.1 - 0.94 9.5 3.2 1.7 8.7 3.2 1.4 1 0 0 1 1 1 0 Frog antimicrobial peptide PhoU PF01895.19 RLN86961.1 - 9.2 6.8 6.8 2 8.9 0.5 2.9 2 1 1 3 3 3 0 PhoU domain AAA_16 PF13191.6 RLN86962.1 - 4.4e-05 23.9 0.0 0.00014 22.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DNA_pol_A_exo1 PF01612.20 RLN86962.1 - 0.00012 21.9 0.2 0.18 11.5 0.0 2.3 2 0 0 2 2 2 2 3'-5' exonuclease AAA_24 PF13479.6 RLN86962.1 - 0.00023 21.0 0.0 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 RLN86962.1 - 0.00035 19.9 0.0 0.00059 19.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA PF00004.29 RLN86962.1 - 0.00039 20.9 0.0 0.0022 18.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 RLN86962.1 - 0.001 18.8 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 RLN86962.1 - 0.0019 18.0 0.1 0.0088 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RLN86962.1 - 0.0021 18.4 0.1 0.036 14.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 RLN86962.1 - 0.0029 18.1 0.0 0.0072 16.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 RLN86962.1 - 0.0031 17.7 0.0 0.0089 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 RLN86962.1 - 0.0038 17.2 0.4 0.32 10.9 0.0 2.4 2 0 0 2 2 2 1 NTPase T2SSE PF00437.20 RLN86962.1 - 0.0063 15.6 0.1 0.012 14.7 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.6 RLN86962.1 - 0.01 15.4 0.4 0.11 12.1 0.0 2.8 4 0 0 4 4 4 0 AAA domain AAA_7 PF12775.7 RLN86962.1 - 0.018 14.6 0.0 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region DLIC PF05783.11 RLN86962.1 - 0.018 13.9 0.0 0.037 12.9 0.0 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_22 PF13401.6 RLN86962.1 - 0.021 15.1 0.6 0.11 12.7 0.2 2.5 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 RLN86962.1 - 0.032 13.8 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 RLN86962.1 - 0.035 14.0 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 RLN86962.1 - 0.036 13.3 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TniB PF05621.11 RLN86962.1 - 0.048 13.1 0.5 7.2 6.0 0.0 2.7 3 0 0 3 3 3 0 Bacterial TniB protein KTI12 PF08433.10 RLN86962.1 - 0.05 13.1 0.1 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_5 PF07728.14 RLN86962.1 - 0.064 13.3 0.0 0.23 11.5 0.0 2.0 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 RLN86962.1 - 0.07 13.7 0.1 0.24 11.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 RLN86962.1 - 0.072 12.9 0.1 0.5 10.2 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 RLN86962.1 - 0.086 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 RLN86962.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 RLN86962.1 - 0.16 12.4 0.0 1.9 8.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ATPase PF06745.13 RLN86962.1 - 0.25 10.7 1.0 2.5 7.4 0.1 2.3 1 1 1 2 2 2 0 KaiC MORN PF02493.20 RLN86964.1 - 7.8e-24 82.1 20.8 0.00027 20.7 0.1 8.2 7 0 0 7 7 7 6 MORN repeat WW PF00397.26 RLN86964.1 - 1.2e-11 44.4 2.7 9.7e-09 35.2 0.5 2.9 2 0 0 2 2 2 2 WW domain IQ PF00612.27 RLN86964.1 - 1.5e-09 36.8 60.3 0.00027 20.5 2.5 9.9 9 0 0 9 9 9 6 IQ calmodulin-binding motif LRR_6 PF13516.6 RLN86964.1 - 4.2e-07 29.5 13.0 3.1 8.1 0.4 8.7 9 0 0 9 9 9 2 Leucine Rich repeat LRR_4 PF12799.7 RLN86964.1 - 6.2e-07 29.7 8.0 3.3 8.3 0.4 7.4 7 1 1 8 8 8 1 Leucine Rich repeats (2 copies) OST-HTH PF12872.7 RLN86964.1 - 0.033 14.0 0.0 0.1 12.4 0.0 1.9 1 0 0 1 1 1 0 OST-HTH/LOTUS domain zf-C2H2_jaz PF12171.8 RLN86964.1 - 0.15 12.4 0.0 22 5.5 0.0 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding LRR_1 PF00560.33 RLN86964.1 - 0.16 12.6 14.2 1.3e+02 3.8 0.1 8.0 8 1 0 8 8 8 0 Leucine Rich Repeat Exo_endo_phos PF03372.23 RLN86965.1 - 1.3e-29 103.4 0.0 2e-29 102.8 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2267 PF10025.9 RLN86965.1 - 0.035 14.4 0.0 0.059 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Exo_endo_phos_2 PF14529.6 RLN86965.1 - 0.054 13.3 0.0 0.57 10.0 0.0 2.2 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase WASH_WAHD PF11945.8 RLN86966.1 - 1.1e-41 143.3 0.1 1.1e-41 143.3 0.1 1.4 2 0 0 2 2 2 1 WAHD domain of WASH complex DUF3464 PF11947.8 RLN86966.1 - 0.084 12.6 0.3 0.084 12.6 0.3 2.0 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 HrpB7 PF09486.10 RLN86966.1 - 1.7 9.0 13.9 0.82 10.0 2.1 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) IQ PF00612.27 RLN86967.1 - 8.5e-21 71.8 57.1 0.0017 18.0 0.0 13.5 13 0 0 13 13 13 8 IQ calmodulin-binding motif BolA PF01722.18 RLN86967.1 - 0.002 18.4 0.1 0.0097 16.2 0.1 2.2 2 0 0 2 2 2 1 BolA-like protein Mpv17_PMP22 PF04117.12 RLN86968.1 - 7.8e-20 70.9 0.7 1.7e-19 69.8 0.7 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.12 RLN86969.1 - 2.7e-22 78.7 0.6 4.2e-22 78.1 0.6 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.12 RLN86970.1 - 2.8e-16 59.5 0.0 4.3e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.12 RLN86971.1 - 2.5e-16 59.6 0.0 3.9e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.12 RLN86972.1 - 3.3e-18 65.7 0.2 6.5e-18 64.7 0.2 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Flavin_Reduct PF01613.18 RLN86972.1 - 7.3e-16 58.6 0.0 1.2e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Mpv17_PMP22 PF04117.12 RLN86973.1 - 1.5e-15 57.1 0.0 2.6e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Secretin PF00263.21 RLN86974.1 - 0.19 11.4 4.6 0.48 10.0 4.6 1.6 1 0 0 1 1 1 0 Bacterial type II and III secretion system protein MARVEL PF01284.23 RLN86975.1 - 8.3e-07 29.1 5.0 1e-06 28.9 5.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain Glug PF07581.12 RLN86975.1 - 0.045 14.2 0.2 0.095 13.2 0.2 1.6 1 0 0 1 1 1 0 The GLUG motif MgtC PF02308.16 RLN86975.1 - 0.07 13.5 3.1 0.084 13.2 3.1 1.1 1 0 0 1 1 1 0 MgtC family Ost5 PF05251.12 RLN86975.1 - 0.11 12.7 6.1 3.3 8.0 0.8 2.1 1 1 1 2 2 2 0 Oligosaccharyltransferase subunit 5 Tom6 PF17112.5 RLN86975.1 - 5.7 6.5 5.4 1.2 8.7 0.5 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom6, fungal MARVEL PF01284.23 RLN86976.1 - 1.7e-20 73.5 27.3 6e-13 49.1 7.9 2.2 2 0 0 2 2 2 2 Membrane-associating domain MNSV_P7B PF06692.11 RLN86976.1 - 0.98 9.5 9.5 1.6 8.8 0.8 3.0 3 0 0 3 3 3 0 Melon necrotic spot virus P7B protein Gram_pos_anchor PF00746.21 RLN86976.1 - 2 8.4 0.0 2 8.4 0.0 2.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif ODV-E18 PF10717.9 RLN86976.1 - 6.9 6.6 5.6 14 5.6 0.1 3.7 4 0 0 4 4 4 0 Occlusion-derived virus envelope protein ODV-E18 Peptidase_C1 PF00112.23 RLN86977.1 - 8.2e-45 153.6 1.9 1.2e-44 153.0 1.9 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RLN86977.1 - 0.0095 14.8 0.4 0.014 14.2 0.4 1.2 1 0 0 1 1 1 1 Peptidase C1-like family Alba PF01918.21 RLN86978.1 - 5.7e-18 64.5 0.3 1.2e-17 63.5 0.3 1.6 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 RLN86978.1 - 8.2e-05 22.6 0.4 8.2e-05 22.6 0.4 2.2 2 1 0 2 2 2 1 Rpp20 subunit of nuclear RNase MRP and P Abhydrolase_1 PF00561.20 RLN86979.1 - 2.7e-27 96.0 0.0 6.7e-20 71.8 0.0 2.4 2 1 1 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN86979.1 - 3.6e-21 76.8 0.0 4.3e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN86979.1 - 3.8e-15 55.8 0.0 4.7e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 RLN86979.1 - 0.00012 22.0 0.0 0.19 11.5 0.0 2.7 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Lipase PF00151.19 RLN86979.1 - 0.00026 20.4 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Lipase BAAT_C PF08840.11 RLN86979.1 - 0.00052 20.0 0.0 0.0013 18.7 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 RLN86979.1 - 0.00064 19.4 0.0 0.0018 18.0 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Palm_thioest PF02089.15 RLN86979.1 - 0.0029 17.5 0.0 0.0035 17.2 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase UPF0227 PF05728.12 RLN86979.1 - 0.0036 17.3 0.2 0.086 12.8 0.2 2.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) DLH PF01738.18 RLN86979.1 - 0.0071 15.9 0.1 4.1 6.9 0.1 2.6 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 RLN86979.1 - 0.017 15.0 0.1 0.046 13.6 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN86979.1 - 0.019 14.5 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 RLN86979.1 - 0.036 13.8 0.0 1.4 8.7 0.0 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase family DUF900 PF05990.12 RLN86979.1 - 0.047 13.2 0.0 0.87 9.1 0.0 2.6 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 RLN86979.1 - 0.076 12.7 0.1 0.22 11.2 0.1 1.8 1 1 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.20 RLN86979.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.6 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.20 RLN86980.1 - 1.7e-29 103.2 0.1 2.7e-27 96.1 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN86980.1 - 1.6e-22 81.2 0.1 2.1e-22 80.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN86980.1 - 1e-16 61.0 0.1 1.4e-16 60.5 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 RLN86980.1 - 6.9e-05 21.7 0.0 0.00013 20.8 0.0 1.4 1 1 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.16 RLN86980.1 - 0.00051 19.9 0.0 0.0056 16.5 0.0 2.5 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 RLN86980.1 - 0.00092 19.2 0.0 0.0018 18.2 0.0 1.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 RLN86980.1 - 0.0011 18.6 0.1 0.028 14.0 0.0 2.6 2 1 0 2 2 2 1 Dienelactone hydrolase family Esterase PF00756.20 RLN86980.1 - 0.017 14.8 0.1 0.042 13.5 0.1 1.6 1 1 0 1 1 1 0 Putative esterase FSH1 PF03959.13 RLN86980.1 - 0.035 13.8 0.0 0.23 11.1 0.0 2.2 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Lipase PF00151.19 RLN86980.1 - 0.056 12.7 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipase IclR PF01614.18 RLN86980.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial transcriptional regulator DsrD PF08679.11 RLN86980.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) Abhydro_lipase PF04083.16 RLN86980.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Palm_thioest PF02089.15 RLN86980.1 - 0.18 11.6 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase N_BRCA1_IG PF16158.5 RLN86981.1 - 7e-29 100.6 0.0 3.1e-28 98.5 0.0 2.1 2 0 0 2 2 2 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 RLN86981.1 - 2.6e-24 84.8 0.4 5e-11 42.2 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, ZZ type PB1 PF00564.24 RLN86981.1 - 5.6e-08 32.6 1.2 3.5e-07 30.1 0.1 2.5 2 0 0 2 2 2 1 PB1 domain UBA PF00627.31 RLN86981.1 - 4.2e-06 26.6 0.3 9.5e-06 25.4 0.3 1.6 1 0 0 1 1 1 1 UBA/TS-N domain DDE_1 PF03184.19 RLN86982.1 - 3.6e-12 46.3 0.0 4.2e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease CPSase_L_D2 PF02786.17 RLN86983.1 - 2.1e-85 285.5 0.0 7.3e-79 264.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 RLN86983.1 - 8.8e-49 164.6 0.0 1.8e-48 163.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 RLN86983.1 - 8.8e-48 162.6 0.0 9.2e-47 159.3 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 RLN86983.1 - 1.4e-39 135.2 0.1 2.4e-39 134.5 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Peptidase_C26 PF07722.13 RLN86983.1 - 2.9e-05 23.9 0.1 0.0039 17.0 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 ATPgrasp_Ter PF15632.6 RLN86983.1 - 0.00021 21.1 0.0 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon DJ-1_PfpI PF01965.24 RLN86983.1 - 0.00029 20.7 0.1 0.22 11.3 0.1 2.6 2 0 0 2 2 2 2 DJ-1/PfpI family ATP-grasp PF02222.22 RLN86983.1 - 0.0017 17.9 0.0 0.14 11.7 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain B12-binding PF02310.19 RLN86983.1 - 0.033 14.2 0.0 0.23 11.5 0.0 2.3 2 0 0 2 2 2 0 B12 binding domain TrkA_N PF02254.18 RLN86983.1 - 0.11 12.8 0.0 3.8 7.8 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain fn3 PF00041.21 RLN86984.1 - 7.4e-16 58.3 3.7 0.087 13.2 0.0 8.5 10 0 0 10 10 10 5 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RLN86984.1 - 1.3e-12 48.1 3.0 1.8 9.2 0.1 7.7 8 0 0 8 8 8 5 Purple acid Phosphatase, N-terminal domain Mid1 PF12929.7 RLN86984.1 - 0.0038 16.5 0.1 2.1 7.4 0.0 3.3 4 0 0 4 4 4 2 Stretch-activated Ca2+-permeable channel component DUF2369 PF10179.9 RLN86984.1 - 0.027 14.9 3.5 1.1 9.7 0.1 4.8 7 0 0 7 7 7 0 Uncharacterised conserved protein (DUF2369) VIT PF08487.10 RLN86984.1 - 0.13 12.5 0.0 2.7 8.2 0.0 2.7 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain AGH PF17558.2 RLN86986.1 - 0.17 12.0 0.3 0.2 11.8 0.3 1.1 1 0 0 1 1 1 0 Androgenic gland hormone HHH_8 PF14716.6 RLN86989.1 - 1.3e-13 51.1 0.1 2.4e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain FAM176 PF14851.6 RLN86989.1 - 0.39 10.4 5.1 0.63 9.7 5.1 1.3 1 0 0 1 1 1 0 FAM176 family DUF913 PF06025.12 RLN86989.1 - 0.57 9.1 3.6 0.72 8.8 3.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 RLN86989.1 - 1.6 7.9 3.1 1.7 7.8 3.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter HSP90 PF00183.18 RLN86989.1 - 1.9 7.3 10.1 2.5 6.9 10.1 1.1 1 0 0 1 1 1 0 Hsp90 protein Vfa1 PF08432.10 RLN86989.1 - 2.4 8.5 13.3 3.3 8.0 13.3 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.12 RLN86989.1 - 2.9 7.6 12.8 4 7.2 12.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 RLN86989.1 - 6.2 5.5 7.1 6.8 5.4 7.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 RLN86989.1 - 6.4 5.4 5.9 6.8 5.3 5.9 1.1 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 RLN86989.1 - 7 6.0 11.1 9.2 5.6 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NTP_transf_2 PF01909.23 RLN86990.1 - 3.6e-05 24.0 0.0 5.7e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Nucleotidyltransferase domain tRNA-synt_1b PF00579.25 RLN86991.1 - 1e-10 41.5 0.0 1.4e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PDZ_6 PF17820.1 RLN86992.1 - 1.1e-16 60.5 0.0 0.00055 19.7 0.0 5.3 5 0 0 5 5 5 4 PDZ domain PDZ PF00595.24 RLN86992.1 - 8.4e-10 38.9 0.0 0.061 13.7 0.0 5.1 5 0 0 5 5 5 3 PDZ domain PDZ_2 PF13180.6 RLN86992.1 - 5.4e-05 23.4 0.0 0.39 11.1 0.0 4.1 4 0 0 4 4 4 2 PDZ domain WD40 PF00400.32 RLN86993.1 - 1e-05 26.2 0.0 1.8 9.6 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat PTCB-BRCT PF12738.7 RLN86994.1 - 1.1e-24 86.1 3.3 2.8e-12 46.4 0.1 4.0 4 0 0 4 4 4 2 twin BRCT domain BRCT PF00533.26 RLN86994.1 - 1.5e-21 76.6 0.0 4e-06 27.1 0.0 5.0 5 0 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 RLN86994.1 - 1.3e-17 63.9 0.0 3.7e-05 24.0 0.0 5.2 5 0 0 5 5 5 4 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 RLN86994.1 - 2.8e-14 53.0 0.7 0.00034 20.6 0.1 5.4 5 1 0 5 5 5 5 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 RLN86994.1 - 3.3e-07 30.5 0.0 0.088 13.1 0.0 3.9 3 0 0 3 3 3 3 DNA ligase 3 BRCT domain zf-HC5HC2H_2 PF13832.6 RLN86996.1 - 0.0043 17.2 1.0 0.0043 17.2 1.0 2.1 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD PF00628.29 RLN86996.1 - 0.0071 16.2 2.4 0.0071 16.2 2.4 2.4 2 0 0 2 2 2 1 PHD-finger Methyltransf_11 PF08241.12 RLN86997.1 - 7e-14 52.3 1.4 2e-13 50.8 0.1 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN86997.1 - 1.2e-11 45.1 0.1 2.2e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN86997.1 - 1.7e-11 44.3 0.0 8.7e-11 41.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN86997.1 - 2.3e-10 41.1 0.1 4.4e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN86997.1 - 1.8e-08 34.3 0.0 3.1e-08 33.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 RLN86997.1 - 0.00012 21.4 0.0 0.00019 20.8 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 RLN86997.1 - 0.00018 21.0 0.1 0.00026 20.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 RLN86997.1 - 0.0019 17.7 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 RLN86997.1 - 0.0061 16.5 0.1 0.01 15.8 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 RLN86997.1 - 0.042 13.5 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Vps5 PF09325.10 RLN86998.1 - 0.027 14.0 4.1 0.14 11.7 3.7 2.0 1 1 0 1 1 1 0 Vps5 C terminal like EF-hand_4 PF12763.7 RLN86998.1 - 0.091 12.7 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DUF16 PF01519.16 RLN86998.1 - 1.3 9.5 4.4 12 6.4 4.4 2.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF281 PF03436.13 RLN86999.1 - 0.029 14.8 0.2 0.085 13.3 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF281) Prenyltrans PF00432.21 RLN86999.1 - 0.05 13.3 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat LINES_N PF14694.6 RLN87000.1 - 4.3e-18 65.9 2.1 4.3e-18 65.9 0.6 1.6 2 0 0 2 2 2 1 Lines N-terminus LINES_C PF14695.6 RLN87000.1 - 1.9e-13 49.6 0.2 7.4e-13 47.7 0.2 2.1 1 0 0 1 1 1 1 Lines C-terminus LisH PF08513.11 RLN87001.1 - 8.8e-07 28.7 0.0 2e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 LisH CLTH PF10607.9 RLN87001.1 - 3.5e-05 23.7 0.2 4.6e-05 23.3 0.2 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain APG6_N PF17675.1 RLN87002.1 - 0.038 14.5 4.5 0.088 13.3 4.5 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 RLN87002.1 - 0.28 11.2 6.3 0.57 10.2 6.3 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc24 PF08286.11 RLN87002.1 - 1 9.6 3.7 0.75 10.1 1.6 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ZapB PF06005.12 RLN87002.1 - 1.1 9.7 6.3 0.84 10.1 4.2 1.9 1 1 0 1 1 1 0 Cell division protein ZapB Nup54 PF13874.6 RLN87002.1 - 5.4 7.1 10.9 20 5.3 6.8 3.0 2 1 2 4 4 4 0 Nucleoporin complex subunit 54 Na_Ca_ex PF01699.24 RLN87004.1 - 2e-42 144.7 34.9 3e-22 79.2 14.5 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein WD40 PF00400.32 RLN87006.1 - 1.2e-46 155.7 10.7 3.4e-07 30.8 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.11 RLN87006.1 - 2.1e-14 52.8 7.5 4.3e-14 51.8 7.5 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 RLN87006.1 - 2.7e-10 40.4 0.4 0.021 15.1 0.0 5.1 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN87006.1 - 1.4 7.5 6.0 12 4.4 0.2 3.8 2 1 3 5 5 5 0 Nucleoporin Nup120/160 PA PF02225.22 RLN87007.1 - 2.6e-05 24.2 0.1 0.00012 22.1 0.0 2.0 2 0 0 2 2 2 1 PA domain PDZ PF00595.24 RLN87007.1 - 8.5e-05 22.8 0.0 0.00018 21.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RLN87007.1 - 0.00046 20.0 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Coatomer_WDAD PF04053.14 RLN87008.1 - 9.9e-123 410.5 0.0 1.4e-122 410.0 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 RLN87008.1 - 3.9e-111 371.7 1.1 1.6e-110 369.6 1.1 1.7 1 1 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 RLN87008.1 - 1.1e-41 139.9 19.6 1.3e-08 35.3 0.2 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN87008.1 - 1.3e-08 35.0 2.1 0.00016 21.9 0.0 5.4 4 2 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain CBFB_NFYA PF02045.15 RLN87009.1 - 1.5e-26 92.8 8.7 1.5e-26 92.8 8.7 1.5 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Laminin_G_2 PF02210.24 RLN87009.1 - 0.17 12.5 0.0 0.19 12.3 0.0 1.2 1 0 0 1 1 1 0 Laminin G domain CP2 PF04516.15 RLN87009.1 - 0.19 11.0 1.3 0.23 10.7 1.3 1.1 1 0 0 1 1 1 0 CP2 transcription factor SAE2 PF08573.10 RLN87009.1 - 2.5 9.2 5.8 5.3 8.2 5.8 1.6 1 1 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus MCD PF05292.11 RLN87010.1 - 1.6e-62 211.5 0.1 4.1e-62 210.1 0.1 1.7 1 1 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain cNMP_binding PF00027.29 RLN87010.1 - 1.9e-05 24.7 0.0 8.1e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Helicase_C PF00271.31 RLN87011.1 - 4.5e-14 52.7 0.0 1.5e-13 51.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain R3H PF01424.22 RLN87011.1 - 3.2e-09 36.7 0.0 7.4e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 R3H domain DEAD PF00270.29 RLN87011.1 - 9.5e-08 32.0 0.0 1.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 RLN87011.1 - 0.067 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 RLN87011.1 - 0.076 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 RLN87011.1 - 0.13 12.5 0.3 0.64 10.3 0.3 2.2 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 RLN87011.1 - 0.15 12.1 0.0 5.3 7.1 0.0 2.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RLN87011.1 - 0.15 11.6 0.0 0.56 9.7 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 RLN87011.1 - 0.2 12.1 0.0 0.44 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 RLN87013.1 - 8.3e-10 39.1 1.6 0.0012 19.7 0.1 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN87013.1 - 1.8e-07 31.4 0.0 0.16 12.3 0.0 4.7 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF573 PF04504.14 RLN87016.1 - 0.039 14.6 1.0 0.063 13.9 1.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF573 Viral_env_E26 PF11050.8 RLN87016.1 - 0.051 12.9 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 Virus envelope protein E26 CTNNB1_binding PF08347.11 RLN87016.1 - 0.091 12.9 2.3 0.11 12.6 2.3 1.2 1 0 0 1 1 1 0 N-terminal CTNNB1 binding FAM194 PF14977.6 RLN87017.1 - 0.04 13.2 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 FAM194 protein DUF89 PF01937.19 RLN87018.1 - 3.5e-24 85.4 0.0 4.4e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 GTP_EFTU_D3 PF03143.17 RLN87019.1 - 3.3e-42 143.3 0.0 6.2e-42 142.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 RLN87019.1 - 4.9e-13 49.3 0.1 9.9e-13 48.3 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 RLN87019.1 - 0.084 12.8 1.2 0.15 12.0 0.2 1.9 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Pyr_redox_2 PF07992.14 RLN87020.1 - 6.6e-56 189.7 1.4 1e-55 189.1 1.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 RLN87020.1 - 1e-29 103.0 0.2 2.2e-29 101.9 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 RLN87020.1 - 3.9e-13 49.8 1.3 1.1e-12 48.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RLN87020.1 - 7.6e-10 38.5 0.0 6.3e-09 35.5 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase zf-TAZ PF02135.16 RLN87020.1 - 1.7e-06 28.4 12.3 3.4e-06 27.4 12.3 1.5 1 0 0 1 1 1 1 TAZ zinc finger K_oxygenase PF13434.6 RLN87020.1 - 0.00052 19.3 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 RLN87020.1 - 0.0017 17.6 0.1 0.0048 16.2 0.1 1.7 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 RLN87020.1 - 0.0023 17.1 1.1 0.0045 16.1 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 RLN87020.1 - 0.0093 16.2 1.9 0.036 14.3 1.9 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 RLN87020.1 - 0.027 13.2 0.2 0.29 9.8 0.3 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 RLN87020.1 - 0.054 12.8 0.1 0.18 11.1 0.2 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase DAO PF01266.24 RLN87020.1 - 1.7 8.1 6.6 0.15 11.6 1.5 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase SKN1 PF03935.15 RLN87021.1 - 1.2e-56 192.2 20.8 7.9e-21 74.0 0.4 4.9 3 2 0 3 3 3 3 Beta-glucan synthesis-associated protein (SKN1) Nodulin_late PF07127.11 RLN87021.1 - 0.26 11.7 2.4 0.6 10.5 0.7 2.4 2 0 0 2 2 2 0 Late nodulin protein Toxin_2 PF00451.19 RLN87021.1 - 0.28 11.5 3.9 0.91 9.9 3.9 2.0 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 Pro_isomerase PF00160.21 RLN87022.1 - 1e-38 133.1 0.0 1.5e-38 132.6 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TetR_C_36 PF18598.1 RLN87022.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PIP5K PF01504.18 RLN87023.1 - 1.6e-64 217.8 0.0 1e-63 215.2 0.0 2.4 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase COesterase PF00135.28 RLN87023.1 - 4.2e-30 105.1 0.0 4.2e-30 105.1 0.0 1.8 2 0 0 2 2 2 1 Carboxylesterase family HALZ PF02183.18 RLN87023.1 - 0.039 14.2 0.4 0.039 14.2 0.4 5.6 4 1 1 5 5 5 0 Homeobox associated leucine zipper BaffR-Tall_bind PF09256.10 RLN87023.1 - 0.18 11.6 1.0 0.53 10.1 1.0 1.8 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding Sulfate_transp PF00916.20 RLN87025.1 - 8.1e-76 255.2 19.0 1.9e-39 135.5 0.3 2.3 2 0 0 2 2 2 2 Sulfate permease family STAS PF01740.21 RLN87025.1 - 1.1e-07 31.5 0.2 1.8e-07 30.8 0.2 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 RLN87025.1 - 0.014 15.7 0.1 0.043 14.2 0.1 1.8 1 0 0 1 1 1 0 STAS domain MFS_MOT1 PF16983.5 RLN87025.1 - 0.017 15.5 15.9 0.03 14.7 4.6 3.2 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily VIR_N PF15912.5 RLN87026.1 - 2.4 7.7 8.9 2.8 7.5 8.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal SWIRM-assoc_2 PF16496.5 RLN87026.1 - 4.3 6.1 15.6 4.7 6.0 15.6 1.0 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal MIF4G PF02854.19 RLN87028.1 - 6.2e-12 45.6 0.0 1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain RskA PF10099.9 RLN87028.1 - 0.003 17.9 0.2 0.0094 16.3 0.2 1.8 1 0 0 1 1 1 1 Anti-sigma-K factor rskA UTP15_C PF09384.10 RLN87028.1 - 0.029 14.1 0.1 0.097 12.3 0.1 1.9 1 0 0 1 1 1 0 UTP15 C terminal RIC3 PF15361.6 RLN87028.1 - 0.85 10.0 0.0 0.85 10.0 0.0 2.7 3 1 0 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 BSP_II PF05432.11 RLN87028.1 - 3.9 7.1 42.8 0.3 10.8 35.0 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) PHF5 PF03660.14 RLN87029.1 - 3.5e-50 168.6 11.8 3.9e-50 168.4 11.8 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 RLN87029.1 - 0.046 11.6 6.1 0.05 11.5 6.1 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Asp PF00026.23 RLN87030.1 - 2.7e-94 316.2 0.0 3.1e-94 315.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RLN87030.1 - 3.1e-09 37.3 0.3 2.1e-05 24.9 0.0 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 RLN87030.1 - 0.038 14.6 0.1 0.83 10.3 0.0 2.8 2 1 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.6 RLN87030.1 - 0.06 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal PGK PF00162.19 RLN87031.1 - 2.9e-147 490.5 6.6 3.3e-147 490.4 6.6 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 RLN87031.1 - 0.00036 20.5 1.4 0.023 14.7 0.0 3.6 2 2 2 4 4 4 1 PA domain HMG_box PF00505.19 RLN87032.1 - 2.4e-36 124.0 12.4 1.2e-19 70.5 3.3 3.0 4 0 0 4 4 4 2 HMG (high mobility group) box HMG_box_2 PF09011.10 RLN87032.1 - 6.1e-26 90.8 12.0 1.2e-12 48.2 3.4 2.6 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 RLN87032.1 - 0.061 13.3 13.0 0.19 11.7 1.3 2.8 1 1 1 2 2 2 0 HMG (high mobility group) box 5 Ccdc124 PF06244.12 RLN87032.1 - 2.7 8.6 14.5 0.32 11.6 5.4 3.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 NDK PF00334.19 RLN87033.1 - 3.7e-08 33.5 0.0 6.2e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 Nucleoside diphosphate kinase ATP_bind_1 PF03029.17 RLN87034.1 - 1.1e-79 267.6 0.2 1.5e-79 267.2 0.2 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 RLN87034.1 - 0.00016 20.7 0.0 0.00042 19.4 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 RLN87034.1 - 0.00039 20.5 0.0 0.00065 19.8 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 RLN87034.1 - 0.00044 20.7 0.3 0.0054 17.1 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 RLN87034.1 - 0.00052 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 RLN87034.1 - 0.0016 18.1 0.0 0.0032 17.1 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 RLN87034.1 - 0.0049 16.2 0.0 0.028 13.7 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin KTI12 PF08433.10 RLN87034.1 - 0.005 16.3 0.0 0.015 14.8 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 MMR_HSR1 PF01926.23 RLN87034.1 - 0.0064 16.6 0.0 0.074 13.1 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 RLN87034.1 - 0.0073 16.6 0.0 0.024 14.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 RLN87034.1 - 0.0097 15.5 0.1 0.12 12.0 0.0 2.5 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 RLN87034.1 - 0.028 14.6 0.0 0.14 12.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RLN87034.1 - 0.036 14.6 0.3 0.23 12.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 RLN87034.1 - 0.047 14.1 0.1 0.12 12.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 RLN87034.1 - 0.049 13.5 0.0 0.44 10.4 0.0 2.1 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RLN87034.1 - 0.093 12.4 0.0 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 RLN87034.1 - 0.14 12.1 0.0 0.48 10.3 0.0 1.8 2 0 0 2 2 2 0 NTPase CLP1_P PF16575.5 RLN87034.1 - 0.15 11.8 0.0 0.46 10.2 0.0 1.8 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_28 PF13521.6 RLN87034.1 - 0.17 12.2 0.3 0.53 10.5 0.1 2.2 2 1 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 RLN87034.1 - 0.17 11.8 0.2 19 5.1 0.0 3.0 2 1 1 3 3 3 0 RsgA GTPase AAA PF00004.29 RLN87034.1 - 0.17 12.3 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Trehalose_PPase PF02358.16 RLN87035.1 - 1e-33 116.5 0.0 1.3e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 RLN87035.1 - 0.061 13.1 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Nuc_sug_transp PF04142.15 RLN87036.1 - 3.5e-43 148.0 9.8 8.5e-43 146.7 9.8 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 RLN87036.1 - 0.0001 22.5 8.6 0.0001 22.5 8.6 2.5 2 1 0 2 2 2 1 EamA-like transporter family Orai-1 PF07856.12 RLN87036.1 - 0.0068 16.1 0.8 0.024 14.3 0.8 1.9 1 0 0 1 1 1 1 Mediator of CRAC channel activity DUF4201 PF13870.6 RLN87037.1 - 7.9e-39 133.2 31.4 7.9e-39 133.2 31.4 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4201) ZapB PF06005.12 RLN87037.1 - 0.05 14.1 0.6 0.05 14.1 0.6 5.3 3 1 2 5 5 5 0 Cell division protein ZapB YabA PF06156.13 RLN87037.1 - 0.2 12.3 27.5 0.32 11.6 4.8 4.3 2 1 2 4 4 4 0 Initiation control protein YabA Myosin_head PF00063.21 RLN87039.1 - 1.7e-201 671.0 0.0 3.2e-201 670.1 0.0 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) PX PF00787.24 RLN87039.1 - 3.2e-11 43.2 0.0 1.1e-10 41.5 0.0 1.9 1 0 0 1 1 1 1 PX domain IQ PF00612.27 RLN87039.1 - 5.7e-05 22.6 19.1 0.16 11.9 0.8 4.8 4 0 0 4 4 4 3 IQ calmodulin-binding motif AAA_22 PF13401.6 RLN87039.1 - 0.01 16.1 0.1 0.068 13.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 RLN87039.1 - 0.064 13.6 0.0 0.064 13.6 0.0 4.1 3 1 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.6 RLN87039.1 - 1.5 9.3 18.5 48 4.4 0.4 3.7 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 RLN87039.1 - 3.8 8.1 6.0 6.8 7.3 0.0 3.5 3 1 0 3 3 3 0 AAA domain FtsJ PF01728.19 RLN87040.1 - 5e-34 117.9 0.1 1.1e-32 113.6 0.0 2.0 1 1 1 2 2 2 2 FtsJ-like methyltransferase 2OG-FeII_Oxy_3 PF13640.6 RLN87041.1 - 2.5e-15 57.1 0.1 1e-14 55.2 0.1 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF1084 PF06454.11 RLN87042.1 - 2.5e-07 30.4 11.0 3.7e-05 23.2 11.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) CH PF00307.31 RLN87043.1 - 2.1e-05 24.7 0.0 0.21 11.8 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain Utp11 PF03998.13 RLN87044.1 - 1.2e-66 225.2 23.3 1.8e-66 224.6 23.3 1.3 1 0 0 1 1 1 1 Utp11 protein Pkinase PF00069.25 RLN87044.1 - 2e-29 102.8 0.0 3.6e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN87044.1 - 3e-24 85.7 0.0 5.2e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Mfp-3 PF04202.13 RLN87044.1 - 0.16 12.4 2.0 7.8 7.0 0.5 2.7 2 0 0 2 2 2 0 Foot protein 3 TIR_2 PF13676.6 RLN87045.1 - 2.8e-11 44.1 0.1 1.4e-08 35.3 0.0 2.6 2 0 0 2 2 2 2 TIR domain BTK PF00779.19 RLN87045.1 - 3.9e-05 23.4 0.9 0.00013 21.7 0.9 1.9 1 0 0 1 1 1 1 BTK motif Nuc_deoxyri_tr2 PF15891.5 RLN87045.1 - 0.056 13.8 0.5 2.9 8.3 0.0 3.2 3 0 0 3 3 3 0 Nucleoside 2-deoxyribosyltransferase like BORCS7 PF16088.5 RLN87045.1 - 0.11 12.7 0.4 4.4 7.6 0.1 2.4 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 7tm_3 PF00003.22 RLN87046.1 - 2.5e-38 132.1 26.9 4.2e-38 131.4 26.9 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peptidase_S8 PF00082.22 RLN87047.1 - 2.3e-44 151.9 6.8 3.6e-44 151.2 6.8 1.3 1 0 0 1 1 1 1 Subtilase family PolyA_pol PF01743.20 RLN87048.1 - 2.7e-26 92.5 0.3 6e-26 91.3 0.3 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 RLN87048.1 - 5.6e-10 38.8 0.0 1.3e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A LPD5 PF18799.1 RLN87048.1 - 0.16 12.4 0.1 0.56 10.6 0.0 1.8 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 5 MFS_1_like PF12832.7 RLN87051.1 - 1.7e-65 221.4 21.3 4.8e-65 219.9 21.3 1.6 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RLN87051.1 - 1.2e-21 77.0 27.3 1.4e-20 73.6 25.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 RLN87051.1 - 6.6e-16 58.1 15.8 1e-15 57.5 15.8 1.2 1 0 0 1 1 1 1 LacY proton/sugar symporter Nuc_H_symport PF03825.16 RLN87051.1 - 1.2e-14 54.2 20.0 2e-14 53.4 20.0 1.3 1 1 0 1 1 1 1 Nucleoside H+ symporter MFS_2 PF13347.6 RLN87051.1 - 4.4e-09 35.4 21.7 6.9e-06 24.9 21.2 2.3 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_3 PF05977.13 RLN87051.1 - 0.00071 18.1 18.5 0.0013 17.2 18.5 1.5 1 1 0 1 1 1 1 Transmembrane secretion effector Pox_P21 PF05313.12 RLN87051.1 - 0.55 9.8 9.1 0.025 14.2 3.3 1.8 2 0 0 2 2 2 0 Poxvirus P21 membrane protein PBP1_TM PF14812.6 RLN87052.1 - 0.071 13.5 4.2 0.13 12.7 4.2 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC27 PF09507.10 RLN87052.1 - 0.23 10.8 5.2 0.35 10.2 5.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Myosin_head PF00063.21 RLN87053.1 - 5.6e-178 593.3 0.0 1.4e-123 413.5 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) ATG16 PF08614.11 RLN87053.1 - 0.018 15.3 10.9 0.046 13.9 10.9 1.7 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) AAA_22 PF13401.6 RLN87053.1 - 0.029 14.6 0.1 0.23 11.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 RLN87053.1 - 0.029 13.4 0.0 0.08 12.0 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF1664 PF07889.12 RLN87053.1 - 0.086 12.9 3.4 0.19 11.8 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Zeta_toxin PF06414.12 RLN87053.1 - 0.11 11.8 0.6 0.7 9.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin PKcGMP_CC PF16808.5 RLN87053.1 - 0.19 11.6 0.7 0.53 10.2 0.7 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase AAA_13 PF13166.6 RLN87053.1 - 0.26 9.9 7.4 0.51 8.9 4.9 2.1 2 0 0 2 2 2 0 AAA domain Cortex-I_coil PF09304.10 RLN87053.1 - 0.31 11.3 6.5 0.81 9.9 6.5 1.7 1 0 0 1 1 1 0 Cortexillin I, coiled coil Fib_alpha PF08702.10 RLN87053.1 - 0.42 10.8 1.9 1.1 9.4 1.9 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 RLN87053.1 - 0.58 10.2 7.6 1.2 9.2 7.6 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 RLN87053.1 - 3.1 7.9 9.8 7.1 6.7 9.8 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IQ PF00612.27 RLN87053.1 - 3.7 7.6 21.5 0.2 11.6 1.3 3.6 3 0 0 3 3 3 0 IQ calmodulin-binding motif GLTSCR1 PF15249.6 RLN87053.1 - 4.7 7.7 9.4 0.27 11.7 0.1 3.4 3 0 0 3 3 3 0 Conserved region of unknown function on GLTSCR protein Adeno_E3B PF03376.14 RLN87054.1 - 0.44 10.8 4.2 0.62 10.3 3.6 1.6 1 1 0 1 1 1 0 Adenovirus E3B protein DEAD PF00270.29 RLN87058.1 - 4e-35 121.2 0.1 7.2e-35 120.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN87058.1 - 1e-23 83.8 0.3 3.2e-23 82.2 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN87058.1 - 3.5e-05 23.9 0.0 6.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 RLN87058.1 - 7.7e-05 22.1 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit RNA_lig_T4_1 PF09511.10 RLN87058.1 - 0.036 13.9 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA ligase MFAP1 PF06991.11 RLN87059.1 - 1.9e-45 155.4 29.9 5.7e-24 85.2 3.8 3.3 3 0 0 3 3 3 3 Microfibril-associated/Pre-mRNA processing FHA PF00498.26 RLN87061.1 - 6.3e-12 45.7 0.1 1.1e-11 44.9 0.1 1.4 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 RLN87061.1 - 0.0013 18.6 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain Yop-YscD_cpl PF16697.5 RLN87061.1 - 0.0054 17.0 0.0 0.11 12.8 0.0 2.3 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF3623 PF12291.8 RLN87061.1 - 0.054 12.7 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3623) HVSL PF09749.9 RLN87062.1 - 6.1e-18 65.2 0.0 1.1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein MAGE PF01454.19 RLN87062.1 - 3.5e-08 33.4 0.0 5.3e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 MAGE family TPR_14 PF13428.6 RLN87063.1 - 3.4e-07 30.5 5.5 0.014 16.1 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat DGCR6 PF07324.11 RLN87063.1 - 1.9e-06 27.6 1.5 3.1e-06 26.9 1.5 1.2 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein Suf PF05843.14 RLN87063.1 - 1.2e-05 25.5 0.0 1.2e-05 25.5 0.0 2.0 1 1 1 2 2 2 1 Suppressor of forked protein (Suf) TPR_19 PF14559.6 RLN87063.1 - 0.00086 19.8 3.5 0.9 10.1 0.0 3.3 2 1 0 3 3 3 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 RLN87063.1 - 0.012 15.5 1.4 0.18 11.8 1.4 2.7 1 1 0 1 1 1 0 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 RLN87063.1 - 0.021 14.9 5.3 3.2 8.1 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 RLN87063.1 - 0.31 11.4 0.8 11 6.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Cpn60_TCP1 PF00118.24 RLN87064.1 - 3.5e-17 62.2 0.1 3.8e-17 62.1 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family LCAT PF02450.15 RLN87065.1 - 2e-80 270.9 0.0 4.3e-80 269.8 0.0 1.5 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.18 RLN87065.1 - 0.002 17.7 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) DUF2613 PF11021.8 RLN87065.1 - 0.11 12.6 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) TMEM117 PF15113.6 RLN87066.1 - 3.8e-09 36.0 1.2 8.7e-09 34.8 1.2 1.6 1 0 0 1 1 1 1 TMEM117 protein family Ion_trans_2 PF07885.16 RLN87066.1 - 5.6e-09 35.8 1.5 5.6e-09 35.8 1.5 2.7 2 0 0 2 2 2 1 Ion channel KleE PF17394.2 RLN87066.1 - 0.56 10.4 9.1 1.7 8.9 2.9 3.1 2 0 0 2 2 2 0 Uncharacterized KleE stable inheritance protein PTR2 PF00854.21 RLN87067.1 - 5.6e-07 28.7 0.8 6e-07 28.6 0.0 1.4 2 0 0 2 2 2 1 POT family DUF872 PF05915.12 RLN87067.1 - 0.25 11.5 4.4 0.31 11.2 3.9 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF5326 PF17260.2 RLN87067.1 - 1 9.5 7.1 1.4 9.1 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5326) PIG-P PF08510.12 RLN87067.1 - 2 8.3 9.1 0.45 10.4 0.4 2.4 1 1 1 2 2 2 0 PIG-P FYVE PF01363.21 RLN87068.1 - 0.1 12.8 8.6 0.18 11.9 8.6 1.4 1 0 0 1 1 1 0 FYVE zinc finger FYVE PF01363.21 RLN87069.1 - 3.4e-06 27.1 15.1 5.8e-06 26.4 15.1 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN87069.1 - 0.049 13.8 12.6 0.21 11.8 12.6 1.9 1 1 1 2 2 2 0 FYVE-type zinc finger FYVE PF01363.21 RLN87070.1 - 7.3e-07 29.2 28.3 1.6e-05 25.0 10.9 2.6 2 0 0 2 2 2 2 FYVE zinc finger FYVE_2 PF02318.16 RLN87071.1 - 0.11 12.8 9.8 0.5 10.6 9.9 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger FYVE PF01363.21 RLN87071.1 - 0.44 10.7 11.6 1 9.6 11.6 1.6 1 0 0 1 1 1 0 FYVE zinc finger PocR PF10114.9 RLN87071.1 - 3.7 7.3 6.8 1.8 8.3 3.8 1.9 1 1 0 2 2 2 0 Sensory domain found in PocR SGL PF08450.12 RLN87072.1 - 2.6e-40 138.6 0.0 3.3e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 RLN87072.1 - 4.5e-05 23.5 0.0 0.0022 18.1 0.0 2.5 2 0 0 2 2 2 1 Strictosidine synthase PQQ_2 PF13360.6 RLN87072.1 - 0.021 14.4 0.1 0.19 11.3 0.1 2.1 1 1 0 1 1 1 0 PQQ-like domain Lactonase PF10282.9 RLN87072.1 - 0.022 14.0 0.0 0.14 11.4 0.0 2.0 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.20 RLN87072.1 - 0.028 14.6 0.0 0.28 11.4 0.0 2.4 2 0 0 2 2 2 0 Arylesterase ANAPC4_WD40 PF12894.7 RLN87072.1 - 0.063 13.6 0.0 0.3 11.4 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-C4pol PF14260.6 RLN87073.1 - 0.18 12.3 9.2 0.53 10.8 8.1 2.4 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta FYVE_2 PF02318.16 RLN87073.1 - 0.79 10.0 10.2 2.5 8.3 10.2 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger C1_2 PF03107.16 RLN87073.1 - 1.2 9.5 7.6 0.58 10.5 4.5 2.1 2 0 0 2 2 2 0 C1 domain zf-piccolo PF05715.13 RLN87073.1 - 9.2 6.5 8.9 1.2 9.3 4.1 2.0 1 1 1 2 2 2 0 Piccolo Zn-finger COX15-CtaA PF02628.15 RLN87074.1 - 1.9e-46 158.6 10.9 7.3e-45 153.4 10.9 2.1 1 1 0 1 1 1 1 Cytochrome oxidase assembly protein DeoC PF01791.9 RLN87074.1 - 3.1e-18 66.2 5.1 4.9e-18 65.6 5.1 1.2 1 0 0 1 1 1 1 DeoC/LacD family aldolase His_biosynth PF00977.21 RLN87074.1 - 0.014 14.9 0.1 0.03 13.8 0.1 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Lum_binding PF00677.17 RLN87075.1 - 7.2e-45 150.9 0.0 1.4e-21 76.3 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain WD40 PF00400.32 RLN87076.1 - 1e-51 171.7 9.4 1.6e-10 41.4 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 RLN87076.1 - 2.2e-34 118.5 0.2 3.5e-34 117.8 0.2 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 RLN87076.1 - 6.1e-12 45.7 0.0 0.0032 17.8 0.0 4.8 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN87076.1 - 1.1e-06 27.7 2.1 0.0071 15.0 0.0 3.7 4 1 0 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 RLN87076.1 - 0.00011 20.9 0.1 0.08 11.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 RLN87076.1 - 0.00051 19.1 0.2 0.71 8.8 0.0 4.0 3 1 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein FMO-like PF00743.19 RLN87079.1 - 1.1e-47 162.7 0.0 1.8e-39 135.6 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 RLN87079.1 - 7.3e-16 58.3 0.0 4.8e-15 55.6 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 RLN87079.1 - 4.3e-06 26.2 0.0 6.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 RLN87079.1 - 0.00079 19.4 0.0 0.2 11.7 0.0 3.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 RLN87079.1 - 0.0016 18.7 0.1 0.0082 16.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 RLN87079.1 - 0.0032 16.7 0.0 0.013 14.7 0.0 1.8 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 RLN87079.1 - 0.025 14.7 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.24 RLN87079.1 - 0.032 13.5 0.1 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 RLN87079.1 - 0.057 12.6 0.0 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain IlvN PF07991.12 RLN87079.1 - 0.15 11.7 0.0 1 8.9 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FMO-like PF00743.19 RLN87081.1 - 1.3e-31 109.7 0.0 1.5e-21 76.4 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 RLN87081.1 - 7.6e-10 38.5 0.0 1.2e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RLN87081.1 - 2e-06 27.2 0.0 5e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 RLN87081.1 - 0.00027 20.3 0.1 0.00079 18.7 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 RLN87082.1 - 4.6e-34 117.7 0.0 1.4e-26 93.1 0.0 2.9 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 RLN87082.1 - 7.9e-15 54.9 0.0 6.6e-14 51.9 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 RLN87082.1 - 7.2e-06 25.4 0.0 1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RLN87082.1 - 0.0034 16.6 0.0 0.0072 15.5 0.0 1.5 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 RLN87082.1 - 0.036 14.1 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 RLN87082.1 - 0.075 13.5 0.1 0.43 11.0 0.1 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding Nuc_sug_transp PF04142.15 RLN87083.1 - 7.7e-10 38.4 2.2 7.7e-10 38.4 2.2 1.5 2 0 0 2 2 2 1 Nucleotide-sugar transporter CRT-like PF08627.10 RLN87083.1 - 0.0012 17.8 5.0 0.0012 17.8 5.0 1.8 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like FYVE PF01363.21 RLN87084.1 - 3.9e-13 49.3 4.4 9.3e-13 48.1 4.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger Sirohm_synth_M PF14824.6 RLN87084.1 - 0.028 13.9 0.4 0.07 12.6 0.4 1.7 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central FYVE_2 PF02318.16 RLN87084.1 - 3.3 7.9 7.6 0.16 12.2 1.2 2.0 3 0 0 3 3 3 0 FYVE-type zinc finger HIP1_clath_bdg PF16515.5 RLN87085.1 - 0.004 17.7 15.2 0.004 17.7 15.2 5.5 1 1 2 5 5 5 2 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2353 PF09789.9 RLN87085.1 - 0.0055 16.1 32.4 0.0055 16.1 32.4 3.2 1 1 2 3 3 3 1 Uncharacterized coiled-coil protein (DUF2353) CCDC144C PF14915.6 RLN87085.1 - 1.4 8.0 76.6 0.15 11.1 26.9 2.3 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region Spc7 PF08317.11 RLN87085.1 - 2.6 6.9 75.3 0.69 8.7 23.9 3.7 1 1 3 4 4 4 0 Spc7 kinetochore protein SHE3 PF17078.5 RLN87086.1 - 1.9e-06 27.8 4.1 2.4e-06 27.4 4.1 1.0 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 NYD-SP28 PF14772.6 RLN87086.1 - 0.0011 18.9 11.2 0.0044 17.0 4.2 2.1 1 1 1 2 2 2 1 Sperm tail GOLGA2L5 PF15070.6 RLN87086.1 - 0.0031 16.2 7.0 0.0041 15.9 7.0 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 bZIP_2 PF07716.15 RLN87086.1 - 0.0057 16.7 1.7 0.0057 16.7 1.7 2.6 1 1 0 2 2 2 1 Basic region leucine zipper Phage_GPO PF05929.11 RLN87086.1 - 0.0057 16.3 2.3 0.0069 16.0 2.3 1.0 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase ATPase PF06745.13 RLN87086.1 - 0.0064 15.9 0.2 0.0079 15.6 0.2 1.1 1 0 0 1 1 1 1 KaiC YabA PF06156.13 RLN87086.1 - 0.0073 16.9 7.2 0.11 13.1 0.4 2.1 1 1 1 2 2 2 1 Initiation control protein YabA Fungal_TACC PF12709.7 RLN87086.1 - 0.0075 16.7 5.3 1.2 9.7 0.1 2.2 2 0 0 2 2 2 2 Fungal Transforming acidic coiled-coil (TACC) proteins GAS PF13851.6 RLN87086.1 - 0.0095 15.3 9.8 0.013 14.8 9.8 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF2046 PF09755.9 RLN87086.1 - 0.013 14.7 8.2 0.4 9.9 0.6 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) PKcGMP_CC PF16808.5 RLN87086.1 - 0.013 15.3 1.6 0.021 14.7 0.1 2.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF2353 PF09789.9 RLN87086.1 - 0.018 14.4 9.1 0.023 14.0 9.1 1.0 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Exonuc_VII_L PF02601.15 RLN87086.1 - 0.02 14.5 2.6 0.023 14.3 2.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 RLN87086.1 - 0.03 12.9 0.7 0.035 12.7 0.7 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Lectin_N PF03954.14 RLN87086.1 - 0.032 14.0 7.0 0.047 13.4 7.0 1.3 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Myb_DNA-bind_4 PF13837.6 RLN87086.1 - 0.032 14.6 1.4 3.8 7.9 0.4 2.2 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain DivIC PF04977.15 RLN87086.1 - 0.061 13.1 0.5 0.061 13.1 0.5 2.9 1 1 2 3 3 3 0 Septum formation initiator AAA_11 PF13086.6 RLN87086.1 - 0.064 13.0 1.9 0.079 12.7 1.9 1.1 1 0 0 1 1 1 0 AAA domain SOGA PF11365.8 RLN87086.1 - 0.091 13.9 8.3 0.53 11.4 0.2 2.1 1 1 1 2 2 2 0 Protein SOGA DUF5094 PF17015.5 RLN87086.1 - 0.11 12.6 3.0 0.14 12.2 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) HAP1_N PF04849.13 RLN87086.1 - 0.12 11.6 12.5 0.21 10.7 12.5 1.4 1 1 0 1 1 1 0 HAP1 N-terminal conserved region MADF_DNA_bdg PF10545.9 RLN87086.1 - 0.18 12.2 4.3 1.6 9.1 1.8 2.1 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Allexi_40kDa PF05549.11 RLN87086.1 - 0.2 11.1 1.8 0.23 10.9 1.8 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein bZIP_1 PF00170.21 RLN87086.1 - 0.21 11.7 6.8 1.1 9.4 1.1 2.4 1 1 1 2 2 2 0 bZIP transcription factor HALZ PF02183.18 RLN87086.1 - 0.21 11.8 8.6 0.24 11.7 0.1 3.1 2 1 1 3 3 3 0 Homeobox associated leucine zipper Prominin PF05478.11 RLN87086.1 - 0.21 9.5 2.2 0.26 9.2 2.2 1.0 1 0 0 1 1 1 0 Prominin PRKG1_interact PF15898.5 RLN87086.1 - 0.22 12.4 9.7 0.35 11.8 9.7 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 RLN87086.1 - 0.28 11.7 13.2 0.46 11.0 13.2 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Mto2_bdg PF12808.7 RLN87086.1 - 0.3 11.4 11.1 0.058 13.7 4.3 2.5 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region FlaC_arch PF05377.11 RLN87086.1 - 0.42 11.0 4.2 19 5.8 0.1 2.8 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) KASH_CCD PF14662.6 RLN87086.1 - 0.53 10.1 12.4 1.6 8.6 12.4 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF1515 PF07439.11 RLN87086.1 - 0.54 10.3 6.7 2.2 8.3 6.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) Golgin_A5 PF09787.9 RLN87086.1 - 0.6 9.5 11.5 0.78 9.1 11.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 FAM76 PF16046.5 RLN87086.1 - 0.66 9.3 7.1 0.8 9.0 7.1 1.1 1 0 0 1 1 1 0 FAM76 protein bZIP_Maf PF03131.17 RLN87086.1 - 0.79 10.3 14.0 0.42 11.2 3.5 2.1 1 1 1 2 2 2 0 bZIP Maf transcription factor Atg14 PF10186.9 RLN87086.1 - 0.92 8.5 7.6 1.2 8.2 7.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_DNA_bd PF12329.8 RLN87086.1 - 0.93 9.5 9.3 0.9 9.6 4.8 2.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 RLN87086.1 - 0.96 8.7 10.4 0.47 9.8 3.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Herpes_BLRF2 PF05812.12 RLN87086.1 - 1 9.5 7.4 3.5 7.8 2.0 2.2 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein Viral_P18 PF04521.13 RLN87086.1 - 1 9.1 3.7 1.2 8.9 0.7 2.0 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF1664 PF07889.12 RLN87086.1 - 1.1 9.4 4.3 1.5 8.9 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF5320 PF17253.2 RLN87086.1 - 1.2 10.3 7.0 1.3e+02 3.7 7.0 2.3 1 1 0 1 1 1 0 Family of unknown function (DUF5320) LCD1 PF09798.9 RLN87086.1 - 1.3 7.5 6.3 1.7 7.0 6.3 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein OmpH PF03938.14 RLN87086.1 - 1.5 9.1 10.9 2.1 8.7 10.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spc24 PF08286.11 RLN87086.1 - 3.1 8.1 11.0 1.8 8.8 0.3 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF1640 PF07798.11 RLN87086.1 - 3.2 7.8 11.9 11 6.0 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF883 PF05957.13 RLN87086.1 - 3.7 8.2 7.0 3.1 8.5 4.7 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Cep57_CLD_2 PF14197.6 RLN87086.1 - 5 7.3 14.5 4.3 7.5 2.1 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Ax_dynein_light PF10211.9 RLN87086.1 - 5.1 7.0 12.5 1.5 8.7 0.3 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain ZapB PF06005.12 RLN87086.1 - 5.3 7.6 15.4 5.4 7.5 4.9 2.2 1 1 1 2 2 2 0 Cell division protein ZapB ABC_tran_CTD PF16326.5 RLN87086.1 - 5.5 7.3 14.0 1.6 9.1 6.1 2.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain MMR_HSR1 PF01926.23 RLN87087.1 - 2.2e-53 179.2 0.0 3.3e-26 91.6 0.0 2.7 3 0 0 3 3 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN87087.1 - 4.7e-31 107.4 0.0 9.6e-18 64.2 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B KH_dom-like PF14714.6 RLN87087.1 - 4.8e-30 103.7 0.1 1.1e-29 102.6 0.1 1.6 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal GTP_EFTU PF00009.27 RLN87087.1 - 1.7e-17 63.6 0.1 1.3e-08 34.6 0.4 4.7 2 2 0 3 3 3 3 Elongation factor Tu GTP binding domain Ras PF00071.22 RLN87087.1 - 1.3e-13 50.9 0.0 4.7e-07 29.5 0.0 2.7 2 1 0 2 2 2 2 Ras family AIG1 PF04548.16 RLN87087.1 - 2.6e-12 46.5 0.0 7e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 AIG1 family Dynamin_N PF00350.23 RLN87087.1 - 1.6e-11 44.6 0.7 0.016 15.3 0.0 4.4 3 1 1 4 4 4 3 Dynamin family RsgA_GTPase PF03193.16 RLN87087.1 - 1.9e-10 40.9 0.2 0.011 15.6 0.0 3.4 3 0 0 3 3 3 3 RsgA GTPase Arf PF00025.21 RLN87087.1 - 2.8e-10 39.9 0.1 0.057 12.9 0.1 3.3 3 0 0 3 3 3 3 ADP-ribosylation factor family Roc PF08477.13 RLN87087.1 - 1.5e-08 34.9 0.1 0.0085 16.3 0.0 3.8 3 2 0 3 3 2 2 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 RLN87087.1 - 4.5e-07 29.5 0.0 0.0016 17.9 0.0 2.2 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 RLN87087.1 - 3.3e-06 27.4 0.1 0.011 16.1 0.0 2.9 3 1 0 3 3 2 2 AAA domain TniB PF05621.11 RLN87087.1 - 4.7e-06 26.2 0.0 0.04 13.3 0.0 2.5 2 0 0 2 2 2 2 Bacterial TniB protein MeaB PF03308.16 RLN87087.1 - 9.1e-06 24.8 0.2 0.26 10.3 0.1 4.0 4 0 0 4 4 4 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 RLN87087.1 - 1.8e-05 25.2 0.0 0.31 11.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter NB-ARC PF00931.22 RLN87087.1 - 0.00036 19.8 0.0 0.14 11.3 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain NTPase_1 PF03266.15 RLN87087.1 - 0.002 18.0 0.3 0.55 10.1 0.0 2.8 2 0 0 2 2 2 1 NTPase AAA_18 PF13238.6 RLN87087.1 - 0.0032 18.0 0.0 4.5 7.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 RLN87087.1 - 0.0065 16.8 0.0 7.5 7.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_29 PF13555.6 RLN87087.1 - 0.0069 16.1 0.0 5 6.9 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 RLN87087.1 - 0.0072 16.1 0.0 1.9 8.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 RLN87087.1 - 0.008 16.1 0.0 4.6 7.1 0.1 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Septin PF00735.18 RLN87087.1 - 0.018 14.4 0.0 3.4 6.9 0.0 2.6 2 0 0 2 2 2 0 Septin AAA_28 PF13521.6 RLN87087.1 - 0.025 14.8 0.0 5.7 7.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 RLN87087.1 - 0.036 14.0 0.1 7.7 6.4 0.0 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 RLN87087.1 - 0.048 13.7 0.0 7.5 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 RLN87087.1 - 0.091 12.5 0.2 2.9 7.6 0.0 3.2 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Ploopntkinase3 PF18751.1 RLN87087.1 - 0.1 12.5 0.0 14 5.5 0.0 2.7 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 ATP_bind_1 PF03029.17 RLN87087.1 - 0.12 12.1 0.1 9 6.0 0.1 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein GBP PF02263.19 RLN87087.1 - 0.16 11.2 0.0 4.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain AAA_16 PF13191.6 RLN87087.1 - 0.27 11.6 2.3 16 5.8 0.0 3.2 3 2 0 3 3 2 0 AAA ATPase domain cobW PF02492.19 RLN87087.1 - 0.84 9.2 3.5 39 3.8 0.0 3.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain zf-met2 PF12907.7 RLN87088.1 - 1.4e-12 47.5 18.1 4e-12 46.1 4.0 4.0 4 0 0 4 4 4 2 Zinc-binding MafB19-deam PF14437.6 RLN87088.1 - 0.00034 20.4 5.1 0.15 11.8 0.7 2.1 2 0 0 2 2 2 2 MafB19-like deaminase Eapp_C PF10238.9 RLN87088.1 - 0.00037 20.6 6.8 0.11 12.5 0.2 2.1 2 0 0 2 2 2 2 E2F-associated phosphoprotein zf-BED PF02892.15 RLN87088.1 - 0.0014 18.6 6.6 0.13 12.3 0.3 2.5 2 0 0 2 2 2 2 BED zinc finger DUF2083 PF09856.9 RLN87088.1 - 0.0023 17.8 1.6 0.43 10.4 0.1 2.2 2 0 0 2 2 2 2 Predicted transcriptional regulator (DUF2083) eIF3g PF12353.8 RLN87088.1 - 0.019 15.4 9.7 0.61 10.5 0.8 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-C2H2_4 PF13894.6 RLN87088.1 - 0.044 14.6 2.0 1.8 9.6 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger PPR_3 PF13812.6 RLN87088.1 - 0.087 12.9 0.0 14 5.8 0.0 2.5 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Peroxin-13_N PF04088.13 RLN87088.1 - 0.14 12.5 1.0 15 5.9 0.1 2.1 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Sin3a_C PF16879.5 RLN87088.1 - 0.15 11.8 8.4 1.2 8.8 1.6 2.1 2 0 0 2 2 2 0 C-terminal domain of Sin3a protein zf-RING_2 PF13639.6 RLN87088.1 - 0.41 11.0 5.1 13 6.2 1.8 2.3 2 0 0 2 2 2 0 Ring finger domain Orf78 PF06024.12 RLN87088.1 - 0.61 10.4 3.0 9 6.7 0.2 2.1 2 0 0 2 2 2 0 Orf78 (ac78) CHD5 PF04420.14 RLN87088.1 - 0.98 9.3 4.4 2.6 7.9 0.2 2.1 2 0 0 2 2 2 0 CHD5-like protein RAM PF15320.6 RLN87088.1 - 1.2 9.8 5.6 2.7 8.7 0.1 2.1 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein Fer4_16 PF13484.6 RLN87088.1 - 1.9 9.5 11.6 5.5 8.0 1.4 2.2 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain PGA2 PF07543.12 RLN87088.1 - 6 6.9 13.0 5.3 7.0 1.9 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 Pep1_7 PF17232.2 RLN87090.1 - 2.1 8.9 4.8 9.7 6.7 4.8 2.2 1 0 0 1 1 1 0 Elicitor peptide 1-7 DUF3138 PF11336.8 RLN87090.1 - 2.8 6.4 20.8 2.5 6.6 6.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3138) DUF4250 PF14056.6 RLN87090.1 - 2.9 7.9 4.2 48 4.0 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) KASH_CCD PF14662.6 RLN87090.1 - 3.5 7.4 35.4 0.97 9.2 10.0 4.0 4 0 0 4 4 4 0 Coiled-coil region of CCDC155 or KASH Laminin_II PF06009.12 RLN87090.1 - 7.4 6.6 21.6 1 9.3 4.1 4.2 3 1 0 3 3 3 0 Laminin Domain II DUF1664 PF07889.12 RLN87090.1 - 9.8 6.2 27.0 0.58 10.2 3.7 4.0 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) Methyltransf_3 PF01596.17 RLN87092.1 - 0.015 14.5 0.0 0.018 14.2 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase Herpes_UL6 PF01763.16 RLN87093.1 - 0.037 12.6 3.0 0.048 12.2 3.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like zf-BED PF02892.15 RLN87093.1 - 0.044 13.8 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 BED zinc finger SET PF00856.28 RLN87094.1 - 5.9e-16 59.3 0.1 3.8e-15 56.7 0.1 1.9 1 1 0 1 1 1 1 SET domain Hist_deacetyl PF00850.19 RLN87095.1 - 1.2e-12 47.9 0.0 1.3e-12 47.8 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Elicitin PF00964.17 RLN87096.1 - 1.7e-21 76.1 0.3 2.2e-21 75.8 0.3 1.1 1 0 0 1 1 1 1 Elicitin Macoilin PF09726.9 RLN87097.1 - 0.38 9.3 4.0 0.44 9.1 4.0 1.1 1 0 0 1 1 1 0 Macoilin family Cpn60_TCP1 PF00118.24 RLN87098.1 - 4.1e-33 114.8 0.7 4.9e-33 114.5 0.7 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Beta_helix_2 PF18835.1 RLN87098.1 - 0.043 13.6 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Beta helix repeat of Inulin fructotransferase Glyco_hydro81C PF17652.1 RLN87099.1 - 9.1e-100 334.3 6.7 1e-99 334.1 6.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain ABC_membrane PF00664.23 RLN87100.1 - 6.4e-83 278.6 23.9 2e-46 158.8 5.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN87100.1 - 5.9e-54 182.3 0.2 2.3e-31 109.1 0.0 3.2 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 RLN87100.1 - 4.8e-12 45.8 2.9 0.0021 17.5 0.0 4.5 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RLN87100.1 - 1.7e-06 28.1 0.2 0.053 13.6 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 RLN87100.1 - 4.9e-06 26.2 0.2 0.077 12.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN87100.1 - 0.00019 21.4 0.4 0.64 9.9 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 RLN87100.1 - 0.0025 18.2 0.5 1.2 9.5 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 RLN87100.1 - 0.0035 17.2 0.0 21 4.8 0.0 3.9 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 RLN87100.1 - 0.0054 16.8 1.6 0.044 13.9 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 RLN87100.1 - 0.011 16.0 0.8 2.8 8.2 0.1 3.1 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 RLN87100.1 - 0.011 16.2 1.3 4.6 7.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 RLN87100.1 - 0.013 15.5 0.1 3.2 7.8 0.0 3.3 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 RLN87100.1 - 0.037 13.0 0.3 4.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 RLN87100.1 - 0.04 13.1 0.2 2.7 7.1 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain cobW PF02492.19 RLN87100.1 - 0.042 13.4 0.5 1.3 8.6 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 RLN87100.1 - 0.046 13.3 0.1 0.65 9.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Roc PF08477.13 RLN87100.1 - 0.051 13.8 0.2 5.2 7.3 0.1 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 RLN87100.1 - 0.059 13.1 0.3 7 6.3 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein Dynamin_N PF00350.23 RLN87100.1 - 0.069 13.2 8.4 0.34 10.9 0.2 3.3 4 0 0 4 4 3 0 Dynamin family AAA_30 PF13604.6 RLN87100.1 - 0.082 12.6 0.8 7.9 6.1 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 RLN87100.1 - 0.083 13.1 0.1 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RLN87100.1 - 0.12 12.3 0.8 6.7 6.6 0.0 2.8 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.6 RLN87100.1 - 0.16 12.5 0.8 9.4 6.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain DUF2070 PF09843.9 RLN87100.1 - 4 5.6 8.2 11 4.2 8.2 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TAFII55_N PF04658.13 RLN87101.1 - 0.00095 18.9 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 TAFII55 protein conserved region MFS_1 PF07690.16 RLN87102.1 - 6.9e-18 64.7 22.0 6.9e-18 64.7 22.0 2.0 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1 PF07690.16 RLN87103.1 - 3.7e-19 68.8 26.9 3.7e-19 68.8 26.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily zf-RING_2 PF13639.6 RLN87104.1 - 2.1e-12 47.2 13.4 2.1e-12 47.2 13.4 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 RLN87104.1 - 8.6e-11 41.4 6.5 2.4e-10 39.9 6.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 RLN87104.1 - 3.5e-06 26.8 9.3 3.5e-06 26.8 9.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN87104.1 - 8.4e-06 26.0 11.9 2.3e-05 24.6 11.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 RLN87104.1 - 3.4e-05 23.6 13.8 3.4e-05 23.6 13.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN87104.1 - 8.7e-05 22.5 6.5 8.7e-05 22.5 6.5 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RLN87104.1 - 0.00014 21.6 9.1 0.00014 21.6 9.1 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN87104.1 - 0.00081 19.2 7.8 0.0017 18.2 7.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN87104.1 - 0.004 17.1 11.1 0.004 17.1 11.1 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 RLN87104.1 - 0.037 14.1 7.3 0.13 12.4 7.3 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 RLN87104.1 - 5 6.8 9.6 12 5.6 9.6 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 RLN87104.1 - 5 7.4 10.2 18 5.6 10.2 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain PDZ PF00595.24 RLN87105.1 - 0.0077 16.6 0.0 2.1 8.7 0.0 2.9 3 0 0 3 3 3 2 PDZ domain ELFV_dehydrog PF00208.21 RLN87106.1 - 2.3e-56 191.2 0.0 2.7e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 RLN87106.1 - 1.5e-29 102.5 0.0 4.1e-27 94.6 0.0 2.5 3 0 0 3 3 3 2 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 RLN87106.1 - 0.0047 17.3 0.0 0.0074 16.7 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Oxidored_nitro PF00148.19 RLN87106.1 - 0.049 12.4 0.0 0.074 11.8 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase 2-Hacid_dh_C PF02826.19 RLN87106.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase PF00069.25 RLN87107.1 - 2.3e-12 46.9 0.0 4.1e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TMEM154 PF15102.6 RLN87107.1 - 4e-05 23.5 0.4 4e-05 23.5 0.4 2.7 2 0 0 2 2 2 1 TMEM154 protein family Orf78 PF06024.12 RLN87107.1 - 0.019 15.2 0.0 0.051 13.9 0.0 1.7 1 0 0 1 1 1 0 Orf78 (ac78) DUF1180 PF06679.12 RLN87107.1 - 0.052 14.0 0.3 0.052 14.0 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Elicitin PF00964.17 RLN87108.1 - 1.6e-11 44.1 0.5 5.6e-08 32.8 0.0 2.5 1 1 1 2 2 2 2 Elicitin DBD_HTH PF18430.1 RLN87108.1 - 0.049 13.4 0.6 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Putative DNA-binding domain MFS_1 PF07690.16 RLN87109.1 - 9.3e-19 67.6 25.2 9.3e-19 67.6 25.2 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily ABC2_membrane PF01061.24 RLN87111.1 - 1.4e-38 132.4 27.0 1.4e-38 132.4 27.0 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RLN87111.1 - 1.1e-18 68.0 0.0 2.9e-18 66.7 0.0 1.7 2 0 0 2 2 2 1 ABC transporter PDR_assoc PF08370.11 RLN87111.1 - 0.00021 20.9 0.6 0.00021 20.9 0.6 2.7 2 0 0 2 2 2 1 Plant PDR ABC transporter associated AAA_16 PF13191.6 RLN87111.1 - 0.0014 19.0 0.0 0.0026 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 RLN87111.1 - 0.0024 17.0 28.9 0.01 14.9 28.9 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_22 PF13401.6 RLN87111.1 - 0.0063 16.8 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 RLN87111.1 - 0.025 14.3 0.7 0.078 12.7 0.3 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 RLN87111.1 - 0.036 13.3 0.0 0.071 12.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 RLN87111.1 - 0.058 13.3 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase DUF815 PF05673.13 RLN87111.1 - 0.14 11.3 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mannosyl_trans2 PF04188.13 RLN87112.1 - 7.7e-61 206.7 20.8 2.4e-60 205.1 20.8 1.7 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) GWT1 PF06423.12 RLN87112.1 - 0.047 13.8 1.7 0.13 12.4 0.0 2.4 2 1 0 2 2 2 0 GWT1 Thioredoxin_8 PF13905.6 RLN87113.1 - 1.9e-17 63.4 0.0 4e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA PF00627.31 RLN87113.1 - 0.0027 17.6 0.3 0.0073 16.2 0.3 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Thioredoxin_2 PF13098.6 RLN87113.1 - 0.018 15.5 0.0 0.062 13.8 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like domain AhpC-TSA PF00578.21 RLN87113.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Ank_2 PF12796.7 RLN87114.1 - 3.8e-36 123.5 19.5 9.7e-08 32.5 0.1 6.5 1 1 8 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN87114.1 - 2.7e-31 107.5 23.4 2e-07 31.4 0.1 10.5 5 3 7 13 13 13 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN87114.1 - 2.3e-22 78.8 21.9 0.0058 16.9 0.0 12.4 4 3 10 14 14 14 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN87114.1 - 3.7e-13 48.4 14.6 2.7 8.9 0.0 12.4 13 1 1 14 14 14 2 Ankyrin repeat Ank PF00023.30 RLN87114.1 - 0.00017 21.9 10.5 5.4 7.6 0.0 8.9 6 1 1 7 7 7 1 Ankyrin repeat Ndc80_HEC PF03801.13 RLN87114.1 - 0.045 13.4 0.0 5.8 6.5 0.0 3.5 4 0 0 4 4 4 0 HEC/Ndc80p family DUF3322 PF11795.8 RLN87114.1 - 0.053 13.5 4.9 6.5 6.7 0.0 4.1 4 1 2 6 6 6 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Il2rg PF15874.5 RLN87114.1 - 0.069 13.4 0.0 30 5.0 0.0 4.0 4 0 0 4 4 4 0 Putative Interleukin 2 receptor, gamma chain PHD PF00628.29 RLN87115.1 - 2.8e-17 62.3 24.3 2.7e-10 40.0 7.6 2.4 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 RLN87115.1 - 1.1e-07 31.2 12.8 0.00026 20.5 2.7 2.5 2 0 0 2 2 2 2 PHD-finger zf-CSL PF05207.13 RLN87115.1 - 0.0019 17.9 3.2 0.0019 17.9 3.2 2.7 2 0 0 2 2 2 1 CSL zinc finger PHD_4 PF16866.5 RLN87115.1 - 0.022 14.9 19.5 0.95 9.6 7.7 2.7 1 1 1 2 2 2 0 PHD-finger C1_1 PF00130.22 RLN87115.1 - 0.1 12.5 14.4 0.049 13.5 2.2 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_S27e PF01667.17 RLN87115.1 - 2 8.2 4.8 2.2 8.1 0.5 2.7 3 0 0 3 3 3 0 Ribosomal protein S27 zf-RING_9 PF13901.6 RLN87115.1 - 3.1 7.7 15.3 10 6.1 4.8 2.3 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon Nse4_C PF08743.10 RLN87119.1 - 1.5e-22 79.6 0.5 3.5e-22 78.4 0.0 1.9 2 0 0 2 2 2 1 Nse4 C-terminal GvpL_GvpF PF06386.11 RLN87119.1 - 1.3 8.9 9.7 2.5 7.9 1.9 2.2 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF TGase_elicitor PF16683.5 RLN87120.1 - 1.2e-180 600.0 3.1 1.4e-180 599.8 3.1 1.1 1 0 0 1 1 1 1 Transglutaminase elicitor Aldo_ket_red PF00248.21 RLN87121.1 - 3.5e-44 151.2 0.3 5e-42 144.1 0.3 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family LON_substr_bdg PF02190.16 RLN87122.1 - 3.6e-36 125.0 1.1 4.6e-36 124.7 0.0 1.7 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 RLN87122.1 - 1.1e-21 77.6 0.2 4e-21 75.8 0.0 2.1 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 RLN87122.1 - 1.6e-06 28.3 0.0 4.6e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 RLN87122.1 - 6.8e-06 26.1 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 RLN87122.1 - 8.7e-06 24.9 0.0 1.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 RLN87122.1 - 4.4e-05 23.3 0.0 0.00032 20.5 0.0 2.5 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RLN87122.1 - 0.00029 21.1 0.2 0.011 16.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN87122.1 - 0.00089 19.7 1.1 0.0036 17.7 0.0 2.5 3 1 1 4 4 4 1 AAA ATPase domain AAA_18 PF13238.6 RLN87122.1 - 0.01 16.4 0.4 0.046 14.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 RLN87122.1 - 0.011 15.6 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_14 PF13173.6 RLN87122.1 - 0.015 15.3 0.0 0.073 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 RLN87122.1 - 0.019 14.1 0.7 0.071 12.3 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain SKI PF01202.22 RLN87122.1 - 0.021 14.9 0.6 0.11 12.6 0.0 2.4 3 0 0 3 3 3 0 Shikimate kinase AAA_7 PF12775.7 RLN87122.1 - 0.045 13.3 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 RLN87122.1 - 0.064 13.6 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 RLN87122.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein RPA_interact_M PF14767.6 RLN87122.1 - 0.32 11.6 4.1 1.9 9.1 0.1 3.5 4 1 0 4 4 3 0 Replication protein A interacting middle AAA_23 PF13476.6 RLN87122.1 - 1.7 9.1 6.6 10 6.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain Lon_C PF05362.13 RLN87123.1 - 1.6e-66 223.8 0.8 7.6e-65 218.3 0.8 2.0 1 1 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.6 RLN87123.1 - 1.3e-05 25.0 0.1 1.9e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase 4HBT_2 PF13279.6 RLN87124.1 - 8e-18 65.1 0.0 9.6e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 RLN87124.1 - 0.026 14.9 0.2 0.053 13.9 0.2 1.4 1 0 0 1 1 1 0 Thioesterase superfamily Acyl-ACP_TE PF01643.17 RLN87124.1 - 0.21 10.8 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Acyl-ACP thioesterase PCNA_N PF00705.18 RLN87125.1 - 5.8e-28 97.2 0.0 6.3e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain UFD1 PF03152.14 RLN87126.1 - 3e-23 82.2 0.0 7.2e-11 41.9 0.0 2.1 1 1 1 2 2 2 2 Ubiquitin fusion degradation protein UFD1 zf-AN1 PF01428.16 RLN87127.1 - 2.1e-09 37.4 7.6 3.8e-09 36.6 7.6 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger 4HBT_2 PF13279.6 RLN87128.1 - 4.5e-08 33.6 0.0 5.4e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT_2 PF13279.6 RLN87129.1 - 2.4e-11 44.2 0.0 2.4e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4246 PF14033.6 RLN87130.1 - 2.6e-82 277.4 0.0 3.3e-81 273.7 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 RLN87130.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 RLN87130.1 - 0.062 14.2 0.0 0.2 12.5 0.0 1.9 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily NAD_binding_10 PF13460.6 RLN87132.1 - 3.3e-12 46.7 0.0 3.4e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 RLN87132.1 - 1.3e-09 38.0 0.0 1.6e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 RLN87132.1 - 0.0015 18.5 0.0 0.0024 17.8 0.0 1.4 1 1 0 1 1 1 1 KR domain Neur_chan_memb PF02932.16 RLN87133.1 - 1.5 8.8 17.1 0.78 9.8 7.5 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Halo_GVPC PF05465.13 RLN87133.1 - 1.7 9.0 7.7 2.1 8.7 0.8 3.2 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat Hamartin PF04388.12 RLN87133.1 - 3.5 6.2 21.3 4.2 5.9 21.3 1.0 1 0 0 1 1 1 0 Hamartin protein Hydrolase_4 PF12146.8 RLN87134.1 - 5.2e-07 29.2 0.1 2.2e-05 23.9 0.0 2.5 2 2 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 RLN87134.1 - 0.00011 21.9 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 RLN87134.1 - 0.00049 20.8 1.1 0.00099 19.8 1.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 RLN87134.1 - 0.017 14.8 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF900 PF05990.12 RLN87134.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) RabGAP-TBC PF00566.18 RLN87135.1 - 1.1e-53 182.1 0.0 2e-53 181.2 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MYCBPAP PF14646.6 RLN87136.1 - 1.4e-66 225.2 0.0 1.4e-66 225.2 0.0 3.0 3 1 1 4 4 4 1 MYCBP-associated protein family PGK PF00162.19 RLN87136.1 - 4.7e-17 62.0 0.0 3e-07 29.7 0.0 3.7 3 1 0 3 3 3 3 Phosphoglycerate kinase Ectoine_synth PF06339.12 RLN87137.1 - 4.5e-18 65.7 0.0 5.8e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Ectoine synthase SLX9 PF15341.6 RLN87138.1 - 4.7e-15 56.1 13.3 4.7e-15 56.1 13.3 1.7 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 AATF-Che1 PF13339.6 RLN87138.1 - 7.7 7.2 11.0 0.75 10.5 5.0 2.3 1 1 2 3 3 3 0 Apoptosis antagonizing transcription factor GpcrRhopsn4 PF10192.9 RLN87139.1 - 0.0014 18.1 0.2 0.11 11.9 0.7 2.1 1 1 1 2 2 2 2 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 RLN87139.1 - 0.0016 17.7 2.0 0.0016 17.7 2.0 1.6 2 0 0 2 2 2 1 Lung seven transmembrane receptor AAA_8 PF12780.7 RLN87140.1 - 2.8e-91 305.4 0.4 1.5e-89 299.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 RLN87140.1 - 1.5e-83 280.6 0.1 9e-83 278.0 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 RLN87140.1 - 6.6e-77 257.6 1.5 1.1e-74 250.2 0.1 3.1 3 0 0 3 3 3 2 ATP-binding dynein motor region AAA_lid_11 PF18198.1 RLN87140.1 - 2.7e-48 163.9 0.0 5.2e-48 163.0 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 RLN87140.1 - 3.6e-39 134.8 10.3 7.6e-39 133.7 10.3 1.5 1 1 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RLN87140.1 - 6.8e-38 129.4 0.5 4e-37 126.9 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 RLN87140.1 - 0.043 13.8 0.5 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF268 PF03269.14 RLN87141.1 - 1.1e-18 67.7 0.0 1.8e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Caenorhabditis protein of unknown function, DUF268 DUF4611 PF15387.6 RLN87141.1 - 0.13 12.5 0.8 0.31 11.3 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Pkinase PF00069.25 RLN87142.1 - 5.1e-52 176.8 0.0 7.9e-49 166.4 0.0 3.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN87142.1 - 5.8e-24 84.8 0.0 2.8e-20 72.7 0.0 2.9 2 1 1 3 3 3 2 Protein tyrosine kinase KHA PF11834.8 RLN87142.1 - 2e-06 27.8 0.0 4.2e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel Kinase-like PF14531.6 RLN87142.1 - 0.0039 16.6 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Glyco_transf_41 PF13844.6 RLN87143.1 - 2.7e-51 174.5 0.2 1.2e-43 149.3 0.2 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 RLN87143.1 - 1.7e-16 58.9 2.9 0.048 13.8 0.0 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 RLN87143.1 - 1.1e-14 53.5 0.2 0.065 13.1 0.0 6.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 RLN87143.1 - 1.3e-11 44.2 10.4 0.012 16.4 0.5 5.6 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 RLN87143.1 - 8.1e-10 39.1 6.8 6.4e-07 29.8 1.2 3.6 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN87143.1 - 1.2e-09 38.7 6.7 0.00035 21.1 0.8 5.0 2 2 2 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN87143.1 - 4.9e-09 35.6 4.5 0.018 15.0 0.1 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN87143.1 - 5.4e-09 36.2 10.0 0.044 14.1 0.7 4.7 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN87143.1 - 4.2e-07 29.7 0.0 0.47 10.8 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN87143.1 - 6.5e-07 29.4 6.0 0.0024 18.0 2.3 3.8 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 RLN87143.1 - 1.1e-06 28.9 3.8 0.77 10.5 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_21 PF09976.9 RLN87143.1 - 1.7e-06 27.9 2.4 5.8e-06 26.1 2.3 1.8 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain TPR_11 PF13414.6 RLN87143.1 - 2.8e-06 26.9 1.9 0.0061 16.2 0.1 4.0 4 0 0 4 4 4 1 TPR repeat ANAPC3 PF12895.7 RLN87143.1 - 0.00082 19.5 0.1 0.34 11.2 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 RLN87143.1 - 0.0036 17.6 0.0 22 5.7 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN87143.1 - 0.01 15.7 6.7 3.4 7.7 0.2 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat HydF_tetramer PF18133.1 RLN87143.1 - 0.042 13.6 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Hydrogen maturase F tetramerization domain SNAP PF14938.6 RLN87143.1 - 0.077 12.4 0.1 0.18 11.2 0.1 1.7 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP Fis1_TPR_C PF14853.6 RLN87143.1 - 0.16 12.1 0.1 0.57 10.3 0.1 2.0 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 RLN87143.1 - 0.17 12.2 3.9 4.5 7.7 0.6 3.8 2 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 RLN87143.1 - 0.2 12.3 9.9 0.28 11.9 0.2 3.9 4 0 0 4 4 2 0 Tetratricopeptide repeat Lyase_1 PF00206.20 RLN87144.1 - 1.2e-112 376.3 0.0 2e-112 375.6 0.0 1.4 1 0 0 1 1 1 1 Lyase LRR_6 PF13516.6 RLN87144.1 - 3.1e-16 58.0 21.8 6.9e-05 22.6 0.1 8.8 9 0 0 9 9 9 5 Leucine Rich repeat LRR_1 PF00560.33 RLN87144.1 - 0.016 15.7 0.1 33 5.6 0.0 5.1 5 1 0 5 5 5 0 Leucine Rich Repeat Foie-gras_1 PF11817.8 RLN87144.1 - 0.023 14.3 0.1 0.04 13.5 0.1 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 LRR_4 PF12799.7 RLN87144.1 - 0.41 11.1 11.4 3.4 8.2 0.1 5.2 4 1 2 6 6 6 0 Leucine Rich repeats (2 copies) PGA2 PF07543.12 RLN87145.1 - 0.25 11.3 8.6 0.3 11.1 8.6 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 RRP14 PF15459.6 RLN87145.1 - 3.3 8.4 14.1 1.6 9.4 6.8 2.2 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 GvpL_GvpF PF06386.11 RLN87145.1 - 4.2 7.2 7.1 0.38 10.6 0.3 1.9 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Herpes_DNAp_acc PF04929.12 RLN87145.1 - 8 5.3 9.2 8.3 5.3 9.2 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Aa_trans PF01490.18 RLN87146.1 - 4.9e-71 239.6 22.2 5.9e-71 239.3 22.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CCB1 PF12046.8 RLN87146.1 - 0.065 12.6 0.0 0.17 11.2 0.0 1.8 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B UQ_con PF00179.26 RLN87147.1 - 5.7e-28 97.3 0.0 6.5e-28 97.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bmt2 PF11968.8 RLN87148.1 - 4e-48 164.2 0.0 5.3e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 RLN87148.1 - 0.00011 22.0 0.0 0.00029 20.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain DUF4670 PF15709.5 RLN87148.1 - 0.069 12.5 4.1 0.092 12.0 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) Methyltransf_12 PF08242.12 RLN87148.1 - 0.15 12.8 0.0 0.58 10.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain XRCC4 PF06632.12 RLN87148.1 - 0.81 8.5 3.1 1.2 8.0 3.1 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 PolyA_pol PF01743.20 RLN87149.1 - 1.4e-26 93.4 0.2 3.2e-26 92.2 0.2 1.7 1 0 0 1 1 1 1 Poly A polymerase head domain tRNA_NucTran2_2 PF13735.6 RLN87149.1 - 2e-06 27.8 0.0 4.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative PolyA_pol_RNAbd PF12627.7 RLN87149.1 - 2.3e-05 24.0 0.0 4.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A DUF2157 PF09925.9 RLN87153.1 - 0.023 14.5 3.4 0.044 13.6 3.4 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Glucos_trans_II PF14264.6 RLN87153.1 - 0.043 13.2 0.4 0.052 12.9 0.4 1.2 1 0 0 1 1 1 0 Glucosyl transferase GtrII Wzy_C PF04932.15 RLN87153.1 - 0.55 9.9 3.1 1.5 8.4 3.2 1.7 1 1 0 1 1 1 0 O-Antigen ligase DUF4131 PF13567.6 RLN87153.1 - 0.75 9.4 5.8 1.2 8.8 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) CPSF_A PF03178.15 RLN87154.1 - 5.6e-90 301.9 0.0 6.3e-90 301.7 0.0 1.0 1 0 0 1 1 1 1 CPSF A subunit region p450 PF00067.22 RLN87155.1 - 5.5e-42 144.1 0.0 6.8e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 2OG-FeII_Oxy_2 PF13532.6 RLN87156.1 - 1.9e-40 139.2 0.0 2.5e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_trans_1_4 PF13692.6 RLN87156.1 - 0.12 12.9 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Palm_thioest PF02089.15 RLN87161.1 - 2.1e-49 168.6 0.0 2.5e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 RLN87161.1 - 9.5e-05 22.1 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN87161.1 - 0.00039 21.1 0.0 0.00068 20.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 RLN87161.1 - 0.00062 19.4 0.0 0.00096 18.8 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase DUF676 PF05057.14 RLN87161.1 - 0.0025 17.4 0.1 0.0057 16.2 0.1 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 RLN87161.1 - 0.0089 15.8 0.8 0.029 14.1 0.0 2.1 3 0 0 3 3 3 1 PGAP1-like protein Lipase_2 PF01674.18 RLN87161.1 - 0.1 12.1 0.1 0.91 9.0 0.1 2.3 1 1 0 1 1 1 0 Lipase (class 2) Nop14 PF04147.12 RLN87162.1 - 1.9e-197 658.4 49.7 2.2e-197 658.2 49.7 1.0 1 0 0 1 1 1 1 Nop14-like family Noc2 PF03715.13 RLN87162.1 - 0.52 9.5 0.0 0.52 9.5 0.0 2.4 3 0 0 3 3 3 0 Noc2p family Ribosomal_S16 PF00886.19 RLN87163.1 - 3.4e-17 62.2 0.1 1.4e-16 60.3 0.1 1.8 1 1 0 1 1 1 1 Ribosomal protein S16 EnY2 PF10163.9 RLN87164.1 - 3.8e-11 43.2 0.0 1.3e-05 25.5 0.0 2.1 2 0 0 2 2 2 2 Transcription factor e(y)2 FHA PF00498.26 RLN87165.1 - 1.2e-07 32.0 0.0 2.4e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Glucan_synthase PF02364.15 RLN87166.1 - 2.9e-187 624.5 11.3 9.8e-184 612.8 11.3 2.4 1 1 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 RLN87166.1 - 2.9e-23 82.6 1.4 4.3e-22 78.8 1.4 2.6 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 CcmE PF03100.15 RLN87166.1 - 0.073 13.1 0.3 0.86 9.6 0.2 2.7 2 0 0 2 2 2 0 CcmE FYVE PF01363.21 RLN87167.1 - 3.7e-13 49.4 8.6 1e-12 48.0 8.6 1.7 1 0 0 1 1 1 1 FYVE zinc finger LegC3_N PF18654.1 RLN87167.1 - 0.019 14.3 4.9 0.051 12.8 4.9 1.7 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain ABC_tran_CTD PF16326.5 RLN87167.1 - 0.29 11.4 2.6 21 5.5 0.4 3.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF5082 PF16888.5 RLN87167.1 - 1.5 9.1 5.5 0.75 10.1 0.8 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) T3SSipB PF16535.5 RLN87167.1 - 1.5 9.3 8.1 6.5 7.2 1.7 3.0 2 0 0 2 2 2 0 Type III cell invasion protein SipB DUF3209 PF11483.8 RLN87167.1 - 2.8 8.4 5.5 1.4 9.4 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3209) FYVE_2 PF02318.16 RLN87167.1 - 3.9 7.7 8.8 0.56 10.4 4.2 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger FYVE PF01363.21 RLN87168.1 - 4.6e-12 45.9 10.7 8.2e-12 45.1 10.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN87168.1 - 0.018 15.3 3.6 0.058 13.6 3.6 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger GAT PF03127.14 RLN87168.1 - 0.14 12.5 0.2 0.33 11.3 0.2 1.7 1 0 0 1 1 1 0 GAT domain Glyco_hydro_1 PF00232.18 RLN87169.1 - 4.3e-122 407.8 0.1 5.3e-122 407.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_1 PF00232.18 RLN87171.1 - 3e-119 398.4 0.0 3.6e-119 398.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF3558 PF12079.8 RLN87171.1 - 0.022 14.8 0.1 0.038 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) Ank_4 PF13637.6 RLN87172.1 - 9.6e-53 175.9 3.7 1.2e-09 38.5 0.1 6.7 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN87172.1 - 2.3e-49 165.9 4.7 2.2e-12 47.4 0.3 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN87172.1 - 4.2e-37 125.7 8.1 6.1e-08 32.8 0.2 7.6 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 RLN87172.1 - 8.9e-35 117.6 11.7 5.2e-05 23.5 0.0 7.5 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 RLN87172.1 - 1.6e-31 104.8 1.4 0.003 17.9 0.0 8.1 8 0 0 8 8 8 8 Ankyrin repeat DUF3952 PF13130.6 RLN87172.1 - 0.028 14.6 0.0 14 5.9 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3952) MccV PF17508.2 RLN87172.1 - 0.47 11.0 10.3 3.3 8.3 0.2 3.5 3 1 0 3 3 3 0 Microcin V bacteriocin AAA_5 PF07728.14 RLN87173.1 - 4.7e-83 276.1 0.0 8.6e-24 84.1 0.0 7.0 6 0 0 6 6 6 6 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 RLN87173.1 - 4.1e-24 84.8 9.5 2.9e-12 46.7 0.3 5.5 5 0 0 5 5 5 2 Midasin AAA lid domain AAA_3 PF07726.11 RLN87173.1 - 6.6e-17 61.6 0.0 2e-06 27.7 0.0 5.4 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 RLN87173.1 - 6.9e-15 55.6 2.8 0.00062 20.2 0.0 5.9 5 1 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 RLN87173.1 - 1.7e-12 47.2 0.0 0.0014 18.1 0.0 4.5 4 0 0 4 4 4 3 P-loop containing dynein motor region Dynein_heavy PF03028.15 RLN87173.1 - 2.2e-12 47.1 0.0 0.0067 16.5 0.0 4.9 4 0 0 4 4 4 3 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 RLN87173.1 - 3.6e-10 40.5 28.9 0.002 18.5 0.1 8.1 8 1 1 9 9 7 4 AAA ATPase domain AAA_22 PF13401.6 RLN87173.1 - 2.5e-09 37.5 10.6 0.016 15.5 0.3 7.1 6 2 0 6 6 5 2 AAA domain AAA_18 PF13238.6 RLN87173.1 - 4e-09 37.1 3.9 0.073 13.6 0.0 6.3 5 0 0 5 5 4 2 AAA domain AAA_6 PF12774.7 RLN87173.1 - 2e-07 30.3 0.1 0.23 10.4 0.0 5.9 6 0 0 6 6 6 2 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 RLN87173.1 - 6.6e-07 29.4 0.1 1.2 9.1 0.0 3.9 4 0 0 4 4 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 RLN87173.1 - 1.2e-06 28.4 0.0 0.07 12.8 0.0 4.0 3 0 0 3 3 3 1 Sigma-54 interaction domain T2SSE PF00437.20 RLN87173.1 - 1.5e-06 27.5 0.0 0.061 12.4 0.0 4.6 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA_14 PF13173.6 RLN87173.1 - 2.7e-06 27.4 0.0 0.22 11.6 0.0 5.1 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.6 RLN87173.1 - 6e-06 26.0 0.6 0.88 9.1 0.0 4.6 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.6 RLN87173.1 - 6.8e-06 26.3 0.2 0.71 10.0 0.0 5.2 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 RLN87173.1 - 9.5e-06 25.1 5.4 0.25 10.7 0.1 6.4 4 2 1 5 5 5 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 RLN87173.1 - 2.2e-05 23.8 1.2 0.92 8.8 0.0 4.8 5 0 0 5 5 5 1 Zeta toxin RuvB_N PF05496.12 RLN87173.1 - 5.3e-05 23.0 0.3 18 5.0 0.0 5.5 5 0 0 5 5 5 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 RLN87173.1 - 0.00017 21.8 12.0 0.2 11.9 0.0 5.2 5 0 0 5 5 4 2 AAA domain AAA_8 PF12780.7 RLN87173.1 - 0.00018 21.0 0.0 1.4 8.2 0.0 4.3 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 NACHT PF05729.12 RLN87173.1 - 0.00051 20.0 0.3 2 8.3 0.0 4.4 4 0 0 4 4 3 1 NACHT domain RNA_helicase PF00910.22 RLN87173.1 - 0.00084 19.7 0.2 31 5.0 0.0 4.2 4 0 0 4 4 3 0 RNA helicase RsgA_GTPase PF03193.16 RLN87173.1 - 0.0022 17.9 2.7 1.4 8.8 0.0 4.2 5 0 0 5 5 3 1 RsgA GTPase Sigma54_activ_2 PF14532.6 RLN87173.1 - 0.0027 17.8 0.1 0.49 10.5 0.0 4.2 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_lid_5 PF17865.1 RLN87173.1 - 0.0046 17.0 4.2 0.0073 16.4 0.1 3.2 3 0 0 3 3 2 1 Midasin AAA lid domain PduV-EutP PF10662.9 RLN87173.1 - 0.0077 16.0 0.1 0.53 10.0 0.0 3.4 4 0 0 4 4 3 1 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 RLN87173.1 - 0.012 15.3 0.0 8.6 6.1 0.0 3.6 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_19 PF13245.6 RLN87173.1 - 0.014 15.7 0.4 9.3 6.6 0.0 4.5 4 0 0 4 4 3 0 AAA domain DUF815 PF05673.13 RLN87173.1 - 0.02 14.1 0.0 2.6 7.1 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 RLN87173.1 - 0.024 14.7 0.5 11 6.2 0.0 4.1 4 0 0 4 4 4 0 50S ribosome-binding GTPase Peptidase_M15_2 PF05951.13 RLN87173.1 - 0.043 13.5 0.5 2.4 7.8 0.0 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF882) ABC_tran PF00005.27 RLN87173.1 - 0.074 13.6 16.1 0.46 11.0 0.0 6.3 7 0 0 7 7 5 0 ABC transporter Rad17 PF03215.15 RLN87173.1 - 0.095 12.6 0.3 12 5.7 0.0 3.8 4 0 0 4 4 4 0 Rad17 P-loop domain SRP54 PF00448.22 RLN87173.1 - 0.16 11.6 1.1 61 3.2 0.0 4.3 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain Roc PF08477.13 RLN87173.1 - 0.22 11.8 1.1 79 3.5 0.0 4.1 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase Ank_2 PF12796.7 RLN87175.1 - 3.3e-07 30.8 0.8 0.17 12.5 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN87175.1 - 1.1e-05 25.6 4.0 0.0046 17.2 0.2 5.5 4 2 3 7 7 7 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN87175.1 - 0.00011 22.7 7.5 0.015 15.9 0.1 5.4 5 3 1 6 6 6 2 Ankyrin repeats (many copies) IQ PF00612.27 RLN87176.1 - 0.0067 16.1 0.6 0.0067 16.1 0.6 2.5 2 0 0 2 2 2 1 IQ calmodulin-binding motif WAPL PF07814.13 RLN87179.1 - 7.6e-10 38.1 3.3 2.7e-07 29.7 0.2 3.0 2 2 0 2 2 2 2 Wings apart-like protein regulation of heterochromatin RCC1 PF00415.18 RLN87180.1 - 3.3e-48 162.1 12.5 8.6e-12 45.5 0.6 6.6 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN87180.1 - 2.5e-22 78.1 22.4 4.3e-06 26.4 0.5 6.1 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Elicitin PF00964.17 RLN87182.1 - 1.5e-17 63.4 0.3 2e-17 63.1 0.3 1.1 1 0 0 1 1 1 1 Elicitin Ank_2 PF12796.7 RLN87184.1 - 2.5e-24 85.7 0.0 2.2e-08 34.5 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN87184.1 - 1.7e-19 69.6 2.4 7.3e-06 26.2 0.2 4.8 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN87184.1 - 3.6e-15 54.6 2.1 0.97 10.2 0.0 7.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 RLN87184.1 - 5e-15 55.7 3.8 0.00014 22.4 0.1 5.9 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN87184.1 - 3.3e-14 52.6 4.5 0.0072 16.7 0.0 6.6 7 0 0 7 7 7 5 Ankyrin repeat IQ PF00612.27 RLN87184.1 - 0.13 12.1 42.7 0.055 13.3 1.2 9.0 8 0 0 8 8 8 0 IQ calmodulin-binding motif DUF2016 PF09436.10 RLN87184.1 - 0.14 12.0 2.2 0.99 9.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF2016) RCC1 PF00415.18 RLN87185.1 - 1.5e-55 185.6 24.4 8.6e-13 48.7 0.3 7.8 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN87185.1 - 7e-33 111.7 32.9 3.6e-06 26.6 2.7 6.7 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat eIF3_p135 PF12807.7 RLN87185.1 - 0.00017 21.6 0.1 0.00033 20.7 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 Tetraspanin PF00335.20 RLN87186.1 - 2.4e-12 47.1 3.5 3.5e-12 46.5 3.5 1.2 1 0 0 1 1 1 1 Tetraspanin family LMBR1 PF04791.16 RLN87186.1 - 0.0053 15.7 0.0 0.0077 15.2 0.0 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF3040 PF11239.8 RLN87186.1 - 3.9 7.8 11.1 8.5 6.7 0.2 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3040) DAHP_synth_1 PF00793.20 RLN87187.1 - 7.1e-96 320.3 0.0 8.8e-96 320.0 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family acVLRF1 PF18859.1 RLN87187.1 - 0.1 12.9 0.2 0.24 11.7 0.2 1.6 1 0 0 1 1 1 0 Actinobacteria/chloroflexi VLRF1 release factor LRAT PF04970.13 RLN87188.1 - 1.2e-09 38.6 0.0 3.9e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 Lecithin retinol acyltransferase P21-Arc PF04062.14 RLN87189.1 - 1.4e-51 175.0 0.5 3.1e-35 121.8 0.0 2.0 1 1 1 2 2 2 2 ARP2/3 complex ARPC3 (21 kDa) subunit DUF469 PF04320.14 RLN87189.1 - 0.074 13.9 0.0 0.11 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein with unknown function (DUF469) pEK499_p136 PF18736.1 RLN87189.1 - 0.083 12.5 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 HEPN pEK499 p136 LRAT PF04970.13 RLN87190.1 - 9.1e-09 35.7 0.1 6.7e-08 32.9 0.1 2.4 1 1 0 1 1 1 1 Lecithin retinol acyltransferase Ribosomal_S25 PF03297.15 RLN87190.1 - 0.023 14.9 0.1 0.049 13.8 0.1 1.4 1 0 0 1 1 1 0 S25 ribosomal protein ADH_N PF08240.12 RLN87191.1 - 1.5e-14 53.7 3.6 2.2e-14 53.3 0.5 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN87191.1 - 6.7e-12 45.5 0.0 1.2e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 RLN87191.1 - 0.015 15.5 0.0 0.032 14.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 RLN87191.1 - 0.048 13.9 0.0 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_11 PF08241.12 RLN87191.1 - 0.15 12.8 0.0 0.29 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Coatomer_E PF04733.14 RLN87192.1 - 1.3e-77 261.1 0.1 1.4e-77 261.0 0.1 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_16 PF13432.6 RLN87192.1 - 4.1e-05 24.1 4.2 0.014 16.0 1.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN87192.1 - 0.00016 22.1 7.1 0.15 12.6 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN87192.1 - 0.00058 20.5 4.2 0.091 13.6 0.5 3.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 RLN87192.1 - 0.00067 19.6 2.9 0.019 15.0 0.5 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN87192.1 - 0.012 15.4 0.6 0.48 10.3 0.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN87192.1 - 0.025 14.8 4.5 0.55 10.6 0.2 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat DAGAT PF03982.13 RLN87193.1 - 2.6e-33 115.2 0.2 1.4e-32 112.8 0.0 2.0 2 0 0 2 2 2 1 Diacylglycerol acyltransferase CUE PF02845.16 RLN87194.1 - 3.1e-10 39.6 1.9 1.7e-08 34.0 0.0 3.1 3 0 0 3 3 3 1 CUE domain zf-RING_2 PF13639.6 RLN87194.1 - 5.8e-05 23.3 8.6 6.9e-05 23.1 2.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 RLN87194.1 - 7.2e-05 22.7 5.1 9.4e-05 22.4 1.6 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RLN87194.1 - 9.2e-05 22.2 2.5 9.2e-05 22.2 2.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN87194.1 - 0.00028 20.5 1.6 0.00028 20.5 1.6 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RLN87194.1 - 0.0074 16.1 4.3 0.0074 16.1 4.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Fibrillarin PF01269.17 RLN87194.1 - 0.06 12.4 0.3 0.092 11.8 0.3 1.2 1 0 0 1 1 1 0 Fibrillarin zf-C3HC4_3 PF13920.6 RLN87194.1 - 0.087 12.7 7.9 1.9 8.4 3.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN87194.1 - 0.26 11.3 9.0 3.4 7.7 9.0 2.4 1 1 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 RLN87194.1 - 4.6 7.6 9.2 4 7.8 4.6 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 RLN87194.1 - 8.2 6.4 8.7 3.1 7.7 0.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Membralin PF09746.9 RLN87195.1 - 3 6.8 18.1 0.32 10.0 10.4 2.2 2 0 0 2 2 2 0 Tumour-associated protein DAGAT PF03982.13 RLN87196.1 - 7.6e-33 113.7 0.0 1.2e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase MSC PF09402.10 RLN87196.1 - 6.1e-11 42.4 0.0 1.9e-10 40.7 0.0 1.8 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain DUF4407 PF14362.6 RLN87196.1 - 0.0056 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) TruB_N PF01509.18 RLN87198.1 - 2e-32 112.6 0.1 3e-20 73.1 0.2 2.1 2 0 0 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) PseudoU_synth_2 PF00849.22 RLN87198.1 - 0.069 13.2 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 RNA pseudouridylate synthase TruB_N PF01509.18 RLN87199.1 - 0.016 15.6 0.0 0.026 14.9 0.0 1.3 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 RLN87199.1 - 0.035 14.3 0.2 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 tRNA pseudouridylate synthase B C-terminal domain DUF848 PF05852.11 RLN87200.1 - 0.01 16.0 0.6 0.014 15.5 0.6 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Mating_N PF12731.7 RLN87200.1 - 0.066 13.3 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Mating-type protein beta 1 Topoisom_bac PF01131.20 RLN87201.1 - 9.7e-100 334.5 0.0 1.2e-99 334.2 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.12 RLN87201.1 - 1.4e-52 175.5 34.9 2e-14 53.4 3.3 4.5 4 0 0 4 4 4 4 GRF zinc finger Toprim PF01751.22 RLN87201.1 - 0.001 19.2 0.0 0.0032 17.7 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Ribosomal_S5_C PF03719.15 RLN87203.1 - 0.094 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain OAD_gamma PF04277.13 RLN87203.1 - 0.16 12.6 0.6 0.23 12.1 0.6 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Cupin_8 PF13621.6 RLN87204.1 - 8.6e-71 238.6 0.2 1.1e-70 238.3 0.2 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 RLN87204.1 - 0.017 15.6 0.0 0.057 13.8 0.0 2.0 1 0 0 1 1 1 0 JmjC domain, hydroxylase Cupin_4 PF08007.12 RLN87204.1 - 0.024 14.1 0.1 0.047 13.1 0.1 1.4 1 0 0 1 1 1 0 Cupin superfamily protein Herpes_PAP PF03325.13 RLN87205.1 - 0.061 12.9 0.4 7.5 6.1 0.0 2.6 3 0 0 3 3 3 0 Herpesvirus polymerase accessory protein FYVE_2 PF02318.16 RLN87205.1 - 0.31 11.2 6.4 0.8 9.9 6.4 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 RLN87205.1 - 7.5 6.8 9.5 21 5.4 9.5 1.8 1 0 0 1 1 1 0 FYVE zinc finger COPI_assoc PF08507.10 RLN87206.1 - 1.7 8.7 3.8 15 5.6 0.1 2.2 2 0 0 2 2 2 0 COPI associated protein TRP PF06011.12 RLN87207.1 - 2e-25 89.4 7.2 2.9e-25 88.9 7.2 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF973 PF06157.11 RLN87207.1 - 3.1 6.8 17.0 0.042 12.9 6.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF973) adh_short PF00106.25 RLN87208.1 - 2.8e-15 56.3 0.1 2.3e-13 50.0 0.1 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN87208.1 - 2e-08 34.1 0.1 2.7e-06 27.1 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Sugar_tr PF00083.24 RLN87209.1 - 1.2e-116 390.2 23.0 1.2e-116 390.2 23.0 1.8 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN87209.1 - 1.1e-17 64.0 35.1 1.1e-17 64.0 35.1 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily FUN14 PF04930.15 RLN87209.1 - 1.6e-17 63.7 0.0 1.6e-17 63.7 0.0 2.7 3 0 0 3 3 3 1 FUN14 family FYVE PF01363.21 RLN87210.1 - 0.00048 20.2 6.4 0.001 19.2 6.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN87210.1 - 0.11 12.7 3.9 0.23 11.7 3.9 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-CRD PF17979.1 RLN87210.1 - 0.23 11.5 3.4 0.42 10.7 3.4 1.4 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions zf-AN1 PF01428.16 RLN87210.1 - 8.9 6.6 8.0 8.2 6.7 4.8 2.4 2 1 0 2 2 2 0 AN1-like Zinc finger FYVE_2 PF02318.16 RLN87212.1 - 0.00034 20.8 4.9 0.00034 20.8 4.9 1.7 2 0 0 2 2 2 1 FYVE-type zinc finger FYVE PF01363.21 RLN87212.1 - 0.0049 17.0 9.4 0.011 15.9 9.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger C1_1 PF00130.22 RLN87212.1 - 0.019 14.9 10.4 0.019 14.9 10.4 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-piccolo PF05715.13 RLN87212.1 - 1 9.6 6.4 2.3 8.4 6.4 1.6 1 0 0 1 1 1 0 Piccolo Zn-finger DZR PF12773.7 RLN87212.1 - 7.8 6.6 10.2 4.1e+02 1.1 10.2 2.5 1 1 0 1 1 1 0 Double zinc ribbon FYVE_2 PF02318.16 RLN87213.1 - 0.02 15.1 2.5 0.037 14.2 2.5 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 RLN87213.1 - 1.8 8.8 9.5 4.9 7.4 9.3 2.0 1 1 0 1 1 1 0 FYVE zinc finger zf-C3HC4_3 PF13920.6 RLN87213.1 - 6.2 6.8 9.7 4.2 7.3 2.7 3.3 1 1 2 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 RLN87214.1 - 0.16 12.2 5.9 0.31 11.2 5.9 1.5 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN87214.1 - 0.39 10.9 6.2 0.25 11.6 4.0 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger FYVE_2 PF02318.16 RLN87215.1 - 0.02 15.1 7.4 0.1 12.8 8.1 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger TPR_1 PF00515.28 RLN87216.1 - 3.7e-13 48.7 13.2 0.00031 20.4 0.2 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 RLN87216.1 - 1.9e-12 47.3 7.3 3.6e-06 27.2 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN87216.1 - 5e-08 32.5 10.7 0.034 14.2 0.2 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat IQ PF00612.27 RLN87216.1 - 1.5e-06 27.5 24.7 0.0051 16.5 0.0 6.5 6 0 0 6 6 6 3 IQ calmodulin-binding motif TPR_10 PF13374.6 RLN87216.1 - 3e-06 26.9 11.3 0.019 14.8 0.1 6.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN87216.1 - 0.00013 21.9 10.4 0.2 11.9 0.5 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 RLN87216.1 - 0.00014 22.1 3.0 1.6 9.6 0.3 4.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN87216.1 - 0.00042 20.9 2.0 2 9.4 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN87216.1 - 0.0058 16.6 5.5 1.2 9.3 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN87216.1 - 0.029 14.1 1.1 6.3 6.6 0.1 3.6 3 0 0 3 3 3 0 TPR repeat PPR PF01535.20 RLN87216.1 - 0.11 12.7 0.3 21 5.7 0.0 3.0 2 0 0 2 2 2 0 PPR repeat ANAPC3 PF12895.7 RLN87216.1 - 1 9.6 5.3 33 4.8 2.8 3.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 CCD48 PF15799.5 RLN87217.1 - 0.084 11.2 0.4 0.13 10.6 0.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 Fib_alpha PF08702.10 RLN87217.1 - 0.43 10.7 2.1 0.68 10.1 2.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 RLN87217.1 - 2.1 9.0 7.2 0.63 10.7 3.0 2.4 2 0 0 2 2 2 0 SlyX ThiF PF00899.21 RLN87218.1 - 3.1e-15 56.2 0.0 4e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family ZZ PF00569.17 RLN87219.1 - 3.3e-07 30.0 0.7 9.4e-07 28.6 0.7 1.8 1 0 0 1 1 1 1 Zinc finger, ZZ type Ank_5 PF13857.6 RLN87219.1 - 0.0011 19.2 0.0 0.0033 17.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF2451 PF10474.9 RLN87219.1 - 0.013 15.3 0.4 1 9.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) NPV_P10 PF05531.12 RLN87219.1 - 0.027 14.9 3.2 0.076 13.5 0.8 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Nsp1_C PF05064.13 RLN87219.1 - 0.027 14.3 7.8 0.1 12.4 2.5 2.9 3 0 0 3 3 3 0 Nsp1-like C-terminal region LPP PF04728.13 RLN87219.1 - 0.1 13.0 2.4 0.27 11.6 2.4 1.7 1 0 0 1 1 1 0 Lipoprotein leucine-zipper DUF1664 PF07889.12 RLN87219.1 - 0.11 12.5 3.4 0.67 10.0 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 RLN87219.1 - 0.17 12.2 4.2 0.86 9.9 0.6 2.8 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Arfaptin PF06456.13 RLN87219.1 - 0.27 10.8 3.2 0.21 11.1 0.7 2.0 2 0 0 2 2 2 0 Arfaptin-like domain DUF148 PF02520.17 RLN87219.1 - 0.37 10.9 2.5 9.2 6.4 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF148 Seryl_tRNA_N PF02403.22 RLN87219.1 - 0.4 10.9 3.6 0.32 11.3 0.4 2.4 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain KxDL PF10241.9 RLN87219.1 - 2.6 8.4 4.4 7.7 6.9 0.3 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein Phage_GP20 PF06810.11 RLN87219.1 - 5.6 6.8 6.2 7 6.4 1.5 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 UPF0242 PF06785.11 RLN87219.1 - 9.9 6.2 9.8 0.62 10.1 3.7 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF456 PF04306.13 RLN87220.1 - 0.11 12.8 1.3 0.24 11.7 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF456) LRR_8 PF13855.6 RLN87222.1 - 2.5e-05 23.9 2.4 0.00036 20.2 2.4 2.5 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 RLN87222.1 - 4e-05 23.9 3.4 7.7e-05 23.0 0.4 2.9 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) DUF4741 PF15897.5 RLN87222.1 - 0.072 12.9 0.2 0.17 11.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4741) LRR_6 PF13516.6 RLN87222.1 - 0.093 12.8 1.6 12 6.2 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 RLN87222.1 - 0.098 13.3 5.1 1.7 9.5 0.3 3.5 3 0 0 3 3 3 0 Leucine Rich Repeat AAA_28 PF13521.6 RLN87222.1 - 0.29 11.3 1.5 2.5 8.3 0.1 2.6 2 1 0 2 2 2 0 AAA domain DSPc PF00782.20 RLN87223.1 - 6e-24 84.4 0.0 1e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Gelsolin PF00626.22 RLN87223.1 - 0.00012 21.9 0.0 0.00081 19.2 0.0 2.1 2 0 0 2 2 2 1 Gelsolin repeat Y_phosphatase PF00102.27 RLN87223.1 - 0.0017 18.0 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 RLN87223.1 - 0.15 11.8 0.1 0.36 10.5 0.1 1.6 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) BRCT PF00533.26 RLN87224.1 - 2.2e-08 34.4 0.0 0.0015 18.9 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 RLN87224.1 - 0.00071 19.9 0.0 0.013 15.9 0.0 2.5 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 RLN87224.1 - 0.00078 19.5 0.0 0.0021 18.1 0.0 1.7 2 0 0 2 2 1 1 BRCA1 C Terminus (BRCT) domain zf-C3HC4 PF00097.25 RLN87224.1 - 0.0015 18.3 12.0 0.0026 17.6 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN87224.1 - 0.0034 17.2 12.2 0.0063 16.3 12.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RTT107_BRCT_5 PF16770.5 RLN87224.1 - 0.016 15.1 0.0 0.052 13.4 0.0 1.9 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain zf-RING_6 PF14835.6 RLN87224.1 - 0.11 12.4 3.7 0.25 11.2 3.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 RLN87224.1 - 0.16 12.2 4.3 0.32 11.2 4.3 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 RLN87224.1 - 0.16 12.1 11.2 0.32 11.2 11.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 RLN87224.1 - 0.17 12.2 12.7 0.32 11.4 12.7 1.4 1 0 0 1 1 1 0 Ring finger domain zf-UDP PF14569.6 RLN87224.1 - 0.2 11.8 1.3 0.5 10.5 1.3 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_UBOX PF13445.6 RLN87224.1 - 0.33 11.0 10.8 0.73 9.9 10.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger FYVE_2 PF02318.16 RLN87224.1 - 0.43 10.8 5.1 1.1 9.5 5.1 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_4 PF14570.6 RLN87224.1 - 0.51 10.2 6.3 1.1 9.1 6.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 RLN87224.1 - 4.4 7.7 9.5 9.8 6.6 9.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RLN87224.1 - 6.4 6.8 12.2 12 5.9 12.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain PIH1_CS PF18201.1 RLN87225.1 - 3.3e-08 33.8 0.0 4.5e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 PIH1 CS-like domain PT PF04886.12 RLN87226.1 - 0.00021 20.8 29.5 0.00021 20.8 29.5 4.2 1 1 2 3 3 3 1 PT repeat Thaumatin PF00314.17 RLN87226.1 - 0.003 17.2 6.0 1.2 8.7 0.4 3.7 3 1 1 4 4 4 3 Thaumatin family Utp14 PF04615.13 RLN87226.1 - 7.9 4.9 7.9 9.9 4.6 7.9 1.1 1 0 0 1 1 1 0 Utp14 protein Methyltransf_16 PF10294.9 RLN87227.1 - 4.7e-29 101.3 0.0 8.4e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase MFS_2 PF13347.6 RLN87227.1 - 5.3e-07 28.5 10.4 5.3e-07 28.5 10.4 2.4 2 0 0 2 2 2 1 MFS/sugar transport protein Methyltransf_25 PF13649.6 RLN87227.1 - 0.00035 21.2 0.1 0.0058 17.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 RLN87227.1 - 0.0029 17.2 0.0 0.0073 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 RLN87227.1 - 0.0077 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 RLN87227.1 - 0.02 14.7 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_12 PF08242.12 RLN87227.1 - 0.02 15.6 0.0 1.3 9.8 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain GidB PF02527.15 RLN87227.1 - 0.025 13.9 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G NNMT_PNMT_TEMT PF01234.17 RLN87227.1 - 0.064 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Met_10 PF02475.16 RLN87227.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Glyco_hydro_125 PF06824.11 RLN87227.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Metal-independent alpha-mannosidase (GH125) WW PF00397.26 RLN87228.1 - 4.7e-22 77.8 15.2 7e-08 32.4 3.9 3.7 3 0 0 3 3 3 3 WW domain Ank PF00023.30 RLN87228.1 - 5e-15 55.2 1.2 0.00049 20.4 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 RLN87228.1 - 8.8e-13 48.7 0.5 2.4e-11 44.0 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN87228.1 - 1.7e-12 46.4 0.3 0.022 15.3 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 RLN87228.1 - 3.8e-11 43.3 0.6 2.2e-08 34.5 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN87228.1 - 1.3e-05 25.4 0.4 0.00088 19.5 0.1 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Glyco_hyd_101C PF17451.2 RLN87228.1 - 0.092 13.0 5.0 0.87 9.9 0.1 3.8 4 0 0 4 4 4 0 Glycosyl hydrolase 101 beta sandwich domain Thaumatin PF00314.17 RLN87230.1 - 0.0034 17.0 0.4 0.033 13.8 0.2 2.2 1 1 1 2 2 2 2 Thaumatin family Apt1 PF10351.9 RLN87230.1 - 0.39 9.5 5.0 0.48 9.2 5.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sporozoite_P67 PF05642.11 RLN87230.1 - 3 5.8 13.3 3.5 5.6 13.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LRR_4 PF12799.7 RLN87231.1 - 5.2e-19 68.0 13.7 9.8e-07 29.0 0.7 5.0 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN87231.1 - 1.1e-16 60.4 12.5 1.6e-07 30.9 0.2 4.0 4 1 0 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 RLN87231.1 - 2e-05 24.2 4.8 0.0036 16.8 1.0 3.9 2 2 1 3 3 3 1 Leucine-rich repeat LRR_6 PF13516.6 RLN87231.1 - 0.0011 18.9 17.1 0.93 9.7 0.2 7.0 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.33 RLN87231.1 - 0.0025 18.1 6.1 3.5 8.5 0.0 5.6 6 1 0 6 6 6 1 Leucine Rich Repeat PIP5K PF01504.18 RLN87232.1 - 2.8e-62 210.4 0.0 4.8e-62 209.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Na_H_Exchanger PF00999.21 RLN87232.1 - 9.5e-08 31.2 7.6 9.5e-08 31.2 7.6 2.0 2 1 0 2 2 2 1 Sodium/hydrogen exchanger family 7tm_2 PF00002.24 RLN87232.1 - 0.00011 21.6 4.8 0.00011 21.6 4.8 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) DUF2721 PF11026.8 RLN87232.1 - 0.024 14.5 0.1 0.024 14.5 0.1 3.7 3 2 1 4 4 4 0 Protein of unknown function (DUF2721) 7tm_1 PF00001.21 RLN87232.1 - 0.15 11.4 11.1 0.4 10.0 11.1 1.7 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) CwsA PF10814.8 RLN87232.1 - 1.8 8.8 7.4 1.2 9.3 0.1 3.2 3 1 0 3 3 3 0 Cell wall synthesis protein CwsA Frizzled PF01534.17 RLN87232.1 - 1.8 7.5 11.5 0.043 12.9 3.2 2.2 2 1 0 2 2 2 0 Frizzled/Smoothened family membrane region Prefoldin PF02996.17 RLN87233.1 - 8.7e-27 93.4 0.5 1.2e-26 93.0 0.5 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 RLN87233.1 - 0.0023 17.9 2.4 0.054 13.5 0.1 2.4 1 1 1 2 2 2 2 Prefoldin subunit DUF2353 PF09789.9 RLN87233.1 - 0.078 12.3 5.1 1.8 7.8 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) SPX PF03105.19 RLN87234.1 - 8.2 6.2 10.0 11 5.8 10.0 1.2 1 0 0 1 1 1 0 SPX domain Thaumatin PF00314.17 RLN87235.1 - 0.0065 16.1 1.5 0.28 10.8 1.5 2.9 1 1 0 1 1 1 1 Thaumatin family EF1_GNE PF00736.19 RLN87236.1 - 2.2e-31 107.9 1.1 3.9e-31 107.1 1.1 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain Ribosomal_60s PF00428.19 RLN87236.1 - 4.4e-05 24.0 9.0 4.4e-05 24.0 9.0 2.9 3 1 1 4 4 3 1 60s Acidic ribosomal protein CDC27 PF09507.10 RLN87236.1 - 0.0055 16.2 11.1 0.0064 15.9 11.1 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Stm1_N PF09598.10 RLN87236.1 - 0.006 17.4 4.2 0.006 17.4 4.2 2.4 2 0 0 2 2 2 1 Stm1 Pox_Ag35 PF03286.14 RLN87236.1 - 0.02 14.7 10.3 0.034 13.9 10.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PBP1_TM PF14812.6 RLN87236.1 - 0.021 15.1 6.4 0.043 14.2 6.4 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EF-1_beta_acid PF10587.9 RLN87236.1 - 0.022 15.2 13.7 0.022 15.2 13.7 3.4 2 1 1 3 3 2 0 Eukaryotic elongation factor 1 beta central acidic region VIR_N PF15912.5 RLN87236.1 - 0.067 12.8 3.5 0.09 12.4 3.5 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Nha1_C PF08619.10 RLN87236.1 - 0.15 11.2 7.5 0.18 10.9 7.5 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Ndc1_Nup PF09531.10 RLN87236.1 - 0.19 10.4 0.2 0.22 10.2 0.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TLP-20 PF06088.11 RLN87236.1 - 0.29 11.0 2.7 0.39 10.6 2.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Fes1 PF08609.10 RLN87236.1 - 0.68 10.8 0.2 0.68 10.8 0.2 2.7 2 1 0 2 2 2 0 Nucleotide exchange factor Fes1 DUF2868 PF11067.8 RLN87236.1 - 0.78 9.2 6.1 0.94 8.9 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) CENP-B_dimeris PF09026.10 RLN87236.1 - 0.82 10.1 10.1 1.7 9.1 10.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 RLN87236.1 - 1 9.0 4.3 1.7 8.3 4.3 1.3 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 RLN87236.1 - 1.9 6.7 7.4 2.6 6.2 7.4 1.2 1 0 0 1 1 1 0 CDC45-like protein PAC1 PF16094.5 RLN87236.1 - 7.3 5.7 6.4 13 4.8 6.4 1.3 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 DNA_pol_phi PF04931.13 RLN87236.1 - 7.9 4.4 11.6 9.7 4.2 11.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nup96 PF12110.8 RLN87237.1 - 1.7e-72 244.0 4.1 2e-72 243.8 2.6 1.8 2 0 0 2 2 2 1 Nuclear protein 96 Nucleoporin2 PF04096.14 RLN87237.1 - 4.2e-38 130.8 0.0 6.9e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Rad60-SLD_2 PF13881.6 RLN87237.1 - 0.0058 16.7 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like N1221 PF07923.13 RLN87237.1 - 0.055 12.6 0.0 0.2 10.8 0.0 1.7 2 0 0 2 2 2 0 N1221-like protein ubiquitin PF00240.23 RLN87237.1 - 0.15 11.8 0.1 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin family Nucleoporin2 PF04096.14 RLN87238.1 - 8.8e-31 107.0 0.0 1.3e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase PH PF00169.29 RLN87238.1 - 2.5e-05 24.7 0.0 5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN87238.1 - 0.21 12.0 0.2 1.1 9.7 0.1 2.0 1 1 1 2 2 2 0 Pleckstrin homology domain MULE PF10551.9 RLN87239.1 - 0.0027 18.1 0.1 0.01 16.2 0.0 2.1 2 0 0 2 2 2 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 RLN87239.1 - 0.032 14.0 0.4 0.12 12.1 0.3 1.9 1 1 0 1 1 1 0 Transposase Ribosomal_L1 PF00687.21 RLN87240.1 - 2.5e-25 89.4 0.0 2.8e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family P2 PF07194.11 RLN87240.1 - 0.21 11.6 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 P2 response regulator binding domain AAA PF00004.29 RLN87241.1 - 1.3e-36 126.0 0.0 3.1e-36 124.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RLN87241.1 - 7e-07 28.9 0.0 3.7e-06 26.7 0.0 2.3 2 0 0 2 2 1 1 AAA+ lid domain Vps4_C PF09336.10 RLN87241.1 - 8.5e-07 28.9 0.1 3e-06 27.1 0.1 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 RLN87241.1 - 2.8e-05 24.3 0.0 5.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 RLN87241.1 - 0.00011 22.2 0.0 0.00053 20.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RLN87241.1 - 0.00026 20.8 0.0 0.0005 19.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RLN87241.1 - 0.00038 20.6 1.4 0.0063 16.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 RLN87241.1 - 0.002 17.6 0.1 0.005 16.3 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 RLN87241.1 - 0.0027 18.1 0.4 0.025 14.9 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 RLN87241.1 - 0.004 16.9 0.0 0.0098 15.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 RLN87241.1 - 0.0095 16.2 0.3 0.17 12.1 0.1 2.7 2 1 1 3 3 3 1 AAA domain AAA_7 PF12775.7 RLN87241.1 - 0.015 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 RLN87241.1 - 0.017 14.3 0.0 0.033 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.13 RLN87241.1 - 0.038 13.2 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Parvo_NS1 PF01057.17 RLN87241.1 - 0.044 12.9 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 RLN87241.1 - 0.048 13.7 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 RLN87241.1 - 0.06 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 RLN87241.1 - 0.06 13.7 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 RLN87241.1 - 0.068 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF1677 PF07911.13 RLN87241.1 - 0.15 12.5 0.7 2.1 8.8 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1677) NTPase_1 PF03266.15 RLN87241.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 NTPase MCM PF00493.23 RLN87241.1 - 0.18 10.9 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_11 PF13086.6 RLN87241.1 - 0.3 10.9 1.9 0.44 10.3 0.2 2.2 2 1 0 2 2 2 0 AAA domain BPL_LplA_LipB PF03099.19 RLN87242.1 - 1.2e-20 73.7 0.0 2.2e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 RLN87242.1 - 0.0031 17.4 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Acetyltransf_6 PF13480.7 RLN87244.1 - 0.045 13.9 0.2 0.079 13.1 0.2 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MDMPI_C PF07398.11 RLN87244.1 - 0.076 13.9 1.6 17 6.3 1.6 2.7 1 1 0 1 1 1 0 MDMPI C-terminal domain Zip PF02535.22 RLN87245.1 - 2.2e-47 161.9 16.5 4.1e-47 161.0 16.5 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter ABC2_membrane PF01061.24 RLN87248.1 - 4.3e-28 98.2 17.1 4.3e-28 98.2 17.1 2.5 2 1 1 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN87248.1 - 4.2e-16 59.7 0.0 6.2e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter PDR_CDR PF06422.12 RLN87248.1 - 1e-05 25.4 2.0 1.1e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 CDR ABC transporter AAA_21 PF13304.6 RLN87248.1 - 4.1e-05 23.6 0.3 0.05 13.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 RLN87248.1 - 0.00042 20.0 0.0 0.00069 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 RLN87248.1 - 0.0016 17.9 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 RLN87248.1 - 0.0067 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN87248.1 - 0.0068 16.1 1.1 0.016 14.9 1.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN87248.1 - 0.035 14.6 0.0 0.057 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RLN87248.1 - 0.15 12.4 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Nuc_deoxyri_tr2 PF15891.5 RLN87249.1 - 8.7e-30 103.2 0.1 1.6e-17 63.8 0.1 2.3 2 0 0 2 2 2 2 Nucleoside 2-deoxyribosyltransferase like LSM PF01423.22 RLN87250.1 - 0.0074 16.0 0.0 0.0091 15.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RLN87250.1 - 0.04 14.0 0.0 0.057 13.6 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Tweety PF04906.13 RLN87251.1 - 1.3e-13 50.4 2.7 1.3e-13 50.4 2.7 1.4 2 0 0 2 2 2 1 Tweety p25-alpha PF05517.12 RLN87251.1 - 0.002 18.3 0.0 0.0034 17.6 0.0 1.3 1 0 0 1 1 1 1 p25-alpha Peptidase_M1 PF01433.20 RLN87253.1 - 3.4e-83 278.5 1.6 5.5e-83 277.8 1.6 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 RLN87253.1 - 1.9e-76 257.6 7.9 2e-76 257.5 5.4 2.3 3 0 0 3 3 3 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 RLN87253.1 - 1.7e-34 119.6 0.0 1.6e-33 116.4 0.0 2.2 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain Cation_ATPase_C PF00689.21 RLN87254.1 - 1.4e-16 60.7 4.1 1.7e-16 60.4 4.1 1.0 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus zf-RVT PF13966.6 RLN87255.1 - 0.00054 20.6 0.3 0.0011 19.7 0.3 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase CMS1 PF14617.6 RLN87256.1 - 0.23 10.7 2.4 0.37 10.1 2.4 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit RWP-RK PF02042.15 RLN87257.1 - 4.6e-10 39.3 0.1 9.1e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain HTH_31 PF13560.6 RLN87257.1 - 0.0054 17.1 1.1 0.014 15.7 1.1 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 RLN87257.1 - 0.091 12.6 0.9 0.2 11.5 0.9 1.6 1 0 0 1 1 1 0 Homeodomain-like domain RWP-RK PF02042.15 RLN87259.1 - 2.1e-09 37.2 0.0 3.2e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain Sigma70_r4_2 PF08281.12 RLN87259.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 PKD_channel PF08016.12 RLN87260.1 - 9.4e-27 93.7 10.4 1.6e-18 66.6 9.1 3.2 2 1 1 3 3 3 3 Polycystin cation channel Ion_trans PF00520.31 RLN87260.1 - 1.8e-11 43.8 12.1 1e-10 41.3 8.0 2.2 2 0 0 2 2 2 2 Ion transport protein SNAP PF14938.6 RLN87261.1 - 2.4e-05 23.9 0.2 6.5e-05 22.5 0.2 1.7 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 RLN87261.1 - 4.9e-05 23.5 31.0 0.0097 16.2 0.2 6.7 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 RLN87261.1 - 0.3 12.0 0.2 0.3 12.0 0.2 6.8 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN87261.1 - 2.8 7.9 17.3 9.5 6.3 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Dynein_C PF18199.1 RLN87262.1 - 6.7e-91 304.7 0.0 7.9e-91 304.5 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 RLN87262.1 - 3.2e-21 75.9 0.0 4.6e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain PKD_channel PF08016.12 RLN87263.1 - 1.2e-23 83.5 15.2 4e-17 62.0 15.2 3.2 2 1 1 3 3 3 3 Polycystin cation channel Ion_trans PF00520.31 RLN87263.1 - 8.8e-05 21.8 20.9 0.00015 21.1 19.3 2.3 2 1 0 2 2 2 1 Ion transport protein DUF373 PF04123.13 RLN87263.1 - 0.3 10.5 6.2 0.59 9.5 6.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DctQ PF04290.12 RLN87263.1 - 0.7 9.8 16.8 0.093 12.6 9.6 2.9 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component PP28 PF10252.9 RLN87264.1 - 1e-21 77.1 20.0 1e-21 77.1 20.0 3.1 3 1 0 3 3 3 1 Casein kinase substrate phosphoprotein PP28 SAP PF02037.27 RLN87264.1 - 1.7e-08 34.0 1.4 3.7e-08 32.9 1.4 1.6 1 0 0 1 1 1 1 SAP domain Thioredoxin PF00085.20 RLN87265.1 - 1.2e-08 34.8 0.1 2.1e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 RLN87265.1 - 0.00037 19.5 0.1 0.00053 19.0 0.1 1.3 1 0 0 1 1 1 1 Phosducin DUF3619 PF12279.8 RLN87265.1 - 0.058 13.7 2.3 0.19 12.0 2.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3619) DUF3037 PF11236.8 RLN87265.1 - 0.12 12.8 1.2 0.27 11.7 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) OmpH PF03938.14 RLN87265.1 - 0.29 11.4 9.3 0.19 12.0 6.9 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF2570 PF10828.8 RLN87265.1 - 3.2 7.6 8.4 0.26 11.1 3.3 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2570) Thioredoxin PF00085.20 RLN87267.1 - 6.2e-43 145.0 3.1 1.1e-23 83.2 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_2 PF13098.6 RLN87267.1 - 3.5e-11 43.5 0.1 1.8e-05 25.1 0.0 3.6 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RLN87267.1 - 2.9e-10 40.3 0.1 0.00037 20.8 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 RLN87267.1 - 3.6e-07 30.3 0.5 0.0027 17.8 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 RLN87267.1 - 3.4e-06 26.6 0.5 0.00041 19.8 0.0 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 RLN87267.1 - 0.00013 21.9 0.8 0.052 13.5 0.1 2.6 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 RLN87267.1 - 0.0002 21.1 0.8 0.47 10.2 0.0 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.6 RLN87267.1 - 0.00089 19.0 1.5 0.035 13.9 0.0 2.8 2 2 0 2 2 2 1 Thioredoxin Nucleocap_ssRNA PF11128.8 RLN87267.1 - 0.0061 16.3 0.1 1.6 8.5 0.0 2.6 2 1 0 2 2 2 1 Plant viral coat protein nucleocapsid Nse4_C PF08743.10 RLN87267.1 - 0.21 11.9 0.5 0.44 10.8 0.5 1.5 1 0 0 1 1 1 0 Nse4 C-terminal ECR1_N PF14382.6 RLN87268.1 - 2e-13 49.9 0.5 4.1e-13 48.9 0.5 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 RLN87268.1 - 1.3e-10 41.5 0.1 3.1e-10 40.2 0.1 1.7 1 0 0 1 1 1 1 KH domain MARVEL PF01284.23 RLN87269.1 - 3e-09 37.1 15.7 4.4e-09 36.5 15.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.12 RLN87269.1 - 1.8e-05 24.6 12.9 3.3e-05 23.7 12.9 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF588) DUF1764 PF08576.10 RLN87270.1 - 5.1e-05 24.1 21.2 5.8e-05 23.9 8.0 3.6 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) DUF2514 PF10721.9 RLN87270.1 - 0.0049 16.9 10.8 0.029 14.4 10.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2514) FlxA PF14282.6 RLN87270.1 - 0.025 14.6 11.3 0.025 14.6 11.3 2.2 2 0 0 2 2 2 0 FlxA-like protein APG6_N PF17675.1 RLN87270.1 - 0.035 14.7 5.6 0.056 14.0 5.6 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Med12-LCEWAV PF12145.8 RLN87270.1 - 0.48 9.2 5.1 0.64 8.8 5.1 1.2 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain Ras PF00071.22 RLN87271.1 - 4e-49 166.3 0.8 5.4e-49 165.9 0.8 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN87271.1 - 1.5e-22 80.1 1.5 1.6e-22 79.9 0.1 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN87271.1 - 9.2e-11 41.5 0.1 1.3e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RLN87271.1 - 0.00052 19.6 0.1 0.00093 18.8 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FAD-SLDH PF12318.8 RLN87271.1 - 0.92 9.6 4.6 1.8 8.6 0.3 2.4 1 1 2 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase FPN1 PF06963.12 RLN87273.1 - 3.8e-91 305.8 13.2 4.4e-91 305.6 13.2 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) DUF1304 PF06993.12 RLN87273.1 - 9.3 6.3 11.9 2.6 8.1 1.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1304) AAA PF00004.29 RLN87274.1 - 1e-40 139.2 0.0 1.7e-40 138.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RLN87274.1 - 3.3e-10 39.6 0.4 6.4e-10 38.7 0.4 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 RLN87274.1 - 1.2e-06 28.8 0.2 0.0029 17.9 0.1 2.3 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 RLN87274.1 - 4.5e-06 26.9 0.0 7.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 RLN87274.1 - 1.9e-05 24.0 0.0 2.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 RLN87274.1 - 3.3e-05 23.9 0.1 0.00025 21.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RLN87274.1 - 7e-05 23.3 0.2 0.0014 19.0 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 RLN87274.1 - 0.00099 18.9 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 RLN87274.1 - 0.0054 16.1 0.1 0.15 11.4 0.1 2.2 1 1 1 2 2 2 1 KaiC TIP49 PF06068.13 RLN87274.1 - 0.0091 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 RLN87274.1 - 0.011 16.1 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 RLN87274.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 RLN87274.1 - 0.011 15.5 0.0 0.037 13.9 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 RLN87274.1 - 0.016 15.1 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain Sigma54_activat PF00158.26 RLN87274.1 - 0.028 14.1 0.0 0.1 12.3 0.0 1.9 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 RLN87274.1 - 0.029 14.1 0.2 0.073 12.8 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RLN87274.1 - 0.04 14.1 0.0 0.07 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 RLN87274.1 - 0.052 13.5 0.2 0.16 11.9 0.1 1.8 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 RLN87274.1 - 0.063 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 RLN87274.1 - 0.063 13.3 0.0 0.096 12.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 RLN87274.1 - 0.069 12.7 0.5 0.53 9.8 0.1 2.2 1 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RLN87274.1 - 0.07 13.7 0.0 0.13 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 RLN87274.1 - 0.086 12.3 0.3 0.19 11.2 0.1 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.6 RLN87274.1 - 0.097 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RLN87274.1 - 0.11 12.0 0.1 0.24 10.9 0.1 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 RLN87274.1 - 0.12 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RLN87274.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MCM PF00493.23 RLN87274.1 - 0.14 11.2 0.0 0.34 10.0 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain DUF2075 PF09848.9 RLN87274.1 - 0.15 11.3 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 RLN87274.1 - 0.17 11.8 0.5 1.9 8.4 0.2 2.5 2 1 0 2 2 2 0 NTPase dsrm PF00035.26 RLN87275.1 - 1.5e-06 28.8 0.0 3.4e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif PH PF00169.29 RLN87275.1 - 0.0092 16.5 0.0 0.021 15.3 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF1043 PF06295.12 RLN87276.1 - 0.11 12.4 0.5 0.15 12.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) dsrm PF00035.26 RLN87279.1 - 1.8e-06 28.6 6.9 0.0021 18.8 0.0 3.3 3 0 0 3 3 3 2 Double-stranded RNA binding motif Fis1_TPR_C PF14853.6 RLN87279.1 - 0.0099 15.9 0.2 0.033 14.2 0.2 1.9 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Peptidase_U32_C PF16325.5 RLN87279.1 - 0.066 13.5 0.1 0.21 11.9 0.1 1.9 1 0 0 1 1 1 0 Peptidase family U32 C-terminal domain TPR_17 PF13431.6 RLN87279.1 - 0.086 13.3 0.8 0.24 11.9 0.8 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN87279.1 - 0.29 11.3 6.7 0.58 10.4 0.7 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ABC_tran_CTD PF16326.5 RLN87279.1 - 0.75 10.1 8.4 9.4 6.6 5.0 3.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain TPR_19 PF14559.6 RLN87279.1 - 1.3 9.5 8.4 0.15 12.6 1.7 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat YfhO PF09586.10 RLN87280.1 - 0.16 10.1 0.4 0.21 9.8 0.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DivIVA PF05103.13 RLN87281.1 - 0.012 15.7 0.0 0.037 14.1 0.0 1.8 1 0 0 1 1 1 0 DivIVA protein KH_1 PF00013.29 RLN87281.1 - 0.067 13.0 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 KH domain DUF1664 PF07889.12 RLN87281.1 - 6.9 6.7 5.8 5.2 7.1 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) MatE PF01554.18 RLN87282.1 - 2.5e-25 89.0 1.9 3e-25 88.7 1.9 1.1 1 0 0 1 1 1 1 MatE Jas PF16135.5 RLN87283.1 - 2.3e-07 30.9 5.1 1.3e-05 25.3 0.3 3.1 3 0 0 3 3 3 2 TPL-binding domain in jasmonate signalling PHD PF00628.29 RLN87283.1 - 0.0048 16.7 5.5 0.0048 16.7 5.5 3.9 5 0 0 5 5 5 1 PHD-finger Zf_RING PF16744.5 RLN87283.1 - 0.044 13.9 3.2 0.17 12.1 3.2 2.0 1 0 0 1 1 1 0 KIAA1045 RING finger c-SKI_SMAD_bind PF08782.10 RLN87283.1 - 7.3 6.9 14.0 3.6 7.9 0.1 3.6 4 0 0 4 4 4 0 c-SKI Smad4 binding domain MAJIN PF15077.6 RLN87283.1 - 9.5 5.9 11.8 14 5.4 10.6 1.9 1 1 0 1 1 1 0 Membrane-anchored junction protein CENP-B_dimeris PF09026.10 RLN87284.1 - 0.022 15.2 13.3 0.027 14.8 13.3 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 RLN87284.1 - 0.19 9.9 5.9 0.18 10.0 5.9 1.0 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 RLN87284.1 - 0.3 10.7 2.5 0.3 10.8 2.5 1.2 1 0 0 1 1 1 0 FAM176 family BUD22 PF09073.10 RLN87284.1 - 0.37 10.1 12.1 0.39 10.0 12.1 1.0 1 0 0 1 1 1 0 BUD22 TRAP_alpha PF03896.16 RLN87284.1 - 1.7 7.8 4.2 1.7 7.8 4.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 RLN87284.1 - 2.1 7.6 9.9 2.4 7.4 9.9 1.1 1 0 0 1 1 1 0 NOA36 protein Astro_capsid_p PF12226.8 RLN87284.1 - 2.5 7.2 9.8 2.9 7.0 9.8 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein EBV-NA3 PF05009.12 RLN87284.1 - 2.5 7.5 5.3 2.8 7.4 5.3 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) YL1 PF05764.13 RLN87284.1 - 3.8 7.5 12.0 4.4 7.4 12.0 1.0 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 RLN87284.1 - 4.1 5.6 7.8 4.1 5.6 7.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 RLN87284.1 - 6.5 4.7 12.2 7.2 4.6 12.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi Patatin PF01734.22 RLN87286.1 - 8.3e-07 29.4 0.1 0.00035 20.8 0.1 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase 7tm_2 PF00002.24 RLN87287.1 - 0.0075 15.6 4.2 0.049 12.9 4.2 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 RLN87287.1 - 0.025 13.7 4.5 0.13 11.4 4.5 2.1 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor Ssl1 PF04056.14 RLN87288.1 - 4.3e-67 225.7 0.0 5.6e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 RLN87288.1 - 3.9e-12 46.8 0.0 7.1e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.12 RLN87288.1 - 3.3e-11 43.2 12.7 3.3e-11 43.2 12.7 2.7 2 0 0 2 2 2 1 TFIIH C1-like domain VWA PF00092.28 RLN87288.1 - 5.1e-08 33.4 0.0 7.4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain IBR PF01485.21 RLN87288.1 - 0.017 15.3 3.3 0.017 15.3 3.3 2.6 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Tfb4 PF03850.14 RLN87288.1 - 0.019 14.5 6.0 0.044 13.3 5.9 1.7 1 1 0 1 1 1 0 Transcription factor Tfb4 Zn-C2H2_12 PF18112.1 RLN87288.1 - 0.29 11.6 3.3 0.93 10.0 3.3 1.9 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain PDZ_6 PF17820.1 RLN87289.1 - 5.4e-16 58.2 0.0 0.0039 17.0 0.0 5.3 5 0 0 5 5 5 4 PDZ domain PDZ PF00595.24 RLN87289.1 - 2.4e-11 43.8 0.0 0.089 13.2 0.0 5.3 5 0 0 5 5 5 4 PDZ domain PDZ_2 PF13180.6 RLN87289.1 - 0.0001 22.6 0.0 0.54 10.6 0.0 4.3 5 0 0 5 5 5 1 PDZ domain Tricorn_PDZ PF14685.6 RLN87289.1 - 0.0027 17.6 0.0 11 6.1 0.0 4.2 4 0 0 4 4 4 1 Tricorn protease PDZ domain WD40 PF00400.32 RLN87290.1 - 0.00042 21.1 0.0 2.1 9.4 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN87290.1 - 0.026 14.8 0.0 1 9.7 0.0 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain tRNA-synt_1b PF00579.25 RLN87291.1 - 7.4e-12 45.2 0.0 1e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-CCCH_4 PF18044.1 RLN87292.1 - 5.2e-06 26.1 1.0 8.8e-06 25.4 1.0 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger NTP_transf_2 PF01909.23 RLN87292.1 - 1.4e-05 25.3 0.0 2.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain zf_CCCH_4 PF18345.1 RLN87292.1 - 0.0015 18.5 0.6 0.003 17.6 0.6 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 RLN87292.1 - 0.0017 18.7 1.1 0.003 18.0 1.1 1.4 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 RLN87292.1 - 0.018 14.9 0.5 0.041 13.8 0.5 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 RLN87292.1 - 0.038 14.7 0.4 0.097 13.4 0.4 1.6 1 0 0 1 1 1 0 Torus domain HHH_8 PF14716.6 RLN87293.1 - 1.3e-13 51.1 0.1 2.4e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain PBP1_TM PF14812.6 RLN87293.1 - 0.0029 17.9 7.7 0.0056 17.0 7.7 1.5 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal FancD2 PF14631.6 RLN87293.1 - 3 5.1 5.6 3.7 4.8 5.6 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease rRNA_proc-arch PF13234.6 RLN87294.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 rRNA-processing arch domain PAF PF15715.5 RLN87294.1 - 0.22 12.1 3.0 0.59 10.7 3.0 1.7 1 0 0 1 1 1 0 PCNA-associated factor histone like domain AAA PF00004.29 RLN87295.1 - 7.2e-35 120.3 0.0 1.6e-34 119.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 RLN87295.1 - 4.7e-08 32.9 0.0 7.7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RLN87295.1 - 1.8e-05 25.1 0.6 0.077 13.3 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_33 PF13671.6 RLN87295.1 - 3.5e-05 24.0 3.3 0.00016 21.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 RLN87295.1 - 0.00011 22.2 0.2 0.0012 18.8 0.2 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Nucleolin_bd PF16725.5 RLN87295.1 - 0.00012 21.6 0.1 0.00031 20.4 0.1 1.6 1 0 0 1 1 1 1 Nucleolin binding domain TIP49 PF06068.13 RLN87295.1 - 0.00029 20.1 0.0 0.0005 19.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 RLN87295.1 - 0.00039 20.1 2.5 0.19 11.3 0.1 3.0 2 1 1 3 3 3 2 AAA domain AAA_2 PF07724.14 RLN87295.1 - 0.00069 19.8 0.5 0.0034 17.5 0.0 2.4 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 RLN87295.1 - 0.00092 19.6 0.5 0.00092 19.6 0.5 3.3 2 2 0 2 2 1 1 AAA ATPase domain NACHT PF05729.12 RLN87295.1 - 0.0018 18.2 1.2 0.044 13.7 0.0 2.9 2 2 1 3 3 3 1 NACHT domain Mg_chelatase PF01078.21 RLN87295.1 - 0.0022 17.4 0.2 0.0074 15.7 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 RLN87295.1 - 0.0028 17.4 0.1 0.0069 16.1 0.1 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 RLN87295.1 - 0.0053 17.1 0.0 0.01 16.2 0.0 1.6 1 1 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 RLN87295.1 - 0.011 16.2 0.4 0.12 12.9 0.0 2.4 2 1 1 3 3 3 0 ABC transporter AAA_14 PF13173.6 RLN87295.1 - 0.029 14.4 0.0 0.084 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain DDE_Tnp_IS66 PF03050.14 RLN87295.1 - 0.033 13.7 2.7 0.054 13.0 2.7 1.3 1 0 0 1 1 1 0 Transposase IS66 family AAA_18 PF13238.6 RLN87295.1 - 0.037 14.6 0.0 0.19 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 RLN87295.1 - 0.053 13.2 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain CPT PF07931.12 RLN87295.1 - 0.058 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF815 PF05673.13 RLN87295.1 - 0.06 12.5 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 RLN87295.1 - 0.066 13.5 1.7 0.12 12.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 RLN87295.1 - 0.068 12.9 3.5 0.41 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 RLN87295.1 - 0.073 13.4 4.3 0.63 10.3 0.0 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_3 PF07726.11 RLN87295.1 - 0.08 12.8 0.0 0.17 11.8 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 RLN87295.1 - 0.099 11.7 0.2 0.46 9.5 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 RLN87295.1 - 0.14 11.7 0.0 0.45 10.0 0.0 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region Rubella_E1 PF05748.11 RLN87295.1 - 0.17 10.7 0.0 0.36 9.7 0.0 1.4 2 0 0 2 2 2 0 Rubella membrane glycoprotein E1 Aldo_ket_red PF00248.21 RLN87296.1 - 3.7e-68 229.9 0.0 4.3e-68 229.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ABC_membrane PF00664.23 RLN87297.1 - 5.2e-25 88.6 19.5 6.5e-25 88.3 19.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_membrane PF00664.23 RLN87298.1 - 1.8e-43 149.2 30.1 3.4e-22 79.4 4.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN87298.1 - 4.4e-35 121.2 0.1 4.1e-18 66.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 RLN87298.1 - 1.1e-05 25.5 0.7 0.03 14.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 RLN87298.1 - 4.8e-05 23.8 0.2 0.01 16.2 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 RLN87298.1 - 0.00065 19.4 1.6 0.92 9.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN87298.1 - 0.0018 18.2 2.2 0.95 9.3 0.5 2.4 2 0 0 2 2 2 2 RsgA GTPase PIG-P PF08510.12 RLN87298.1 - 0.0024 17.8 2.9 0.011 15.6 2.9 2.2 1 0 0 1 1 1 1 PIG-P AAA_18 PF13238.6 RLN87298.1 - 0.0034 17.9 0.1 0.67 10.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RLN87298.1 - 0.0036 17.6 0.1 0.6 10.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 RLN87298.1 - 0.0046 16.8 0.2 6.8 6.4 0.0 3.2 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RLN87298.1 - 0.0054 16.2 1.2 3 7.2 0.2 3.1 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 RLN87298.1 - 0.0083 15.9 0.1 0.91 9.2 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Dynamin_N PF00350.23 RLN87298.1 - 0.012 15.7 3.8 1.6 8.8 1.1 2.4 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.6 RLN87298.1 - 0.012 16.2 0.1 2.2 8.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 RLN87298.1 - 0.024 13.7 0.0 0.55 9.2 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 RLN87298.1 - 0.036 14.2 3.5 0.41 10.7 0.1 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 RLN87298.1 - 0.048 14.1 0.2 4.4 7.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.13 RLN87298.1 - 0.052 12.7 1.0 2.3 7.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 RLN87298.1 - 0.061 12.8 0.2 3.7 7.0 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 RLN87298.1 - 0.092 12.1 1.2 8.3 5.7 0.2 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 RLN87298.1 - 0.11 11.7 0.6 1.4 8.2 0.2 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 RLN87298.1 - 0.12 11.9 0.5 3.2 7.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 RLN87298.1 - 0.13 12.4 0.1 1.8 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 RLN87298.1 - 0.19 10.8 0.9 11 5.1 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.9 RLN87298.1 - 0.31 10.8 1.7 19 5.0 0.1 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation BT1 PF03092.16 RLN87299.1 - 8.1e-74 248.7 17.7 5.1e-42 143.8 5.5 2.8 1 1 2 3 3 3 3 BT1 family PUCC PF03209.15 RLN87299.1 - 0.0005 19.2 2.3 0.0005 19.2 2.3 1.7 2 0 0 2 2 2 1 PUCC protein Annexin PF00191.20 RLN87300.1 - 9.6e-66 217.8 2.0 3.4e-17 62.3 0.0 4.2 4 0 0 4 4 4 4 Annexin DUF3848 PF12959.7 RLN87300.1 - 0.037 14.1 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) baeRF_family12 PF18856.1 RLN87300.1 - 0.048 14.2 0.2 4.3 7.9 0.0 2.8 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 12 Annexin PF00191.20 RLN87301.1 - 7.9e-55 182.8 1.5 3.7e-14 52.5 0.0 4.1 4 0 0 4 4 4 4 Annexin DNA_ligase_A_N PF04675.14 RLN87301.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.7 1 1 0 1 1 1 0 DNA ligase N terminus PTEN_C2 PF10409.9 RLN87304.1 - 7.7e-10 38.6 0.0 1.1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 RLN87304.1 - 1.6e-06 28.0 0.0 2.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RLN87304.1 - 0.00034 20.2 0.0 0.00056 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RLN87304.1 - 0.0029 17.6 0.1 0.0051 16.8 0.1 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPn PF14671.6 RLN87304.1 - 0.041 14.3 0.0 0.084 13.3 0.0 1.4 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.6 RLN87304.1 - 0.064 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate BRK PF07533.16 RLN87304.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 BRK domain N6-adenineMlase PF10237.9 RLN87305.1 - 1.6e-34 119.0 0.0 2.6e-34 118.4 0.0 1.3 1 1 0 1 1 1 1 Probable N6-adenine methyltransferase CRAL_TRIO PF00650.20 RLN87306.1 - 1.8e-33 115.5 0.0 4e-33 114.4 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain STPPase_N PF16891.5 RLN87306.1 - 2e-20 73.0 0.1 4.1e-20 72.0 0.1 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 RLN87306.1 - 5.1e-18 66.3 0.0 1.2e-17 65.1 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PH PF00169.29 RLN87306.1 - 5.4e-09 36.5 0.0 1.2e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF1179 PF06678.11 RLN87306.1 - 0.53 10.3 3.5 0.69 9.9 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) IQ PF00612.27 RLN87307.1 - 3e-10 38.9 16.1 0.0037 16.9 0.0 5.1 4 0 0 4 4 4 4 IQ calmodulin-binding motif HRI1 PF16815.5 RLN87307.1 - 1.3 8.7 6.0 4.5 6.9 6.0 1.8 1 1 0 1 1 1 0 Protein HRI1 GTP_EFTU PF00009.27 RLN87308.1 - 3.3e-47 160.5 0.2 3.7e-47 160.4 0.2 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RLN87308.1 - 5.6e-06 26.4 0.0 0.0027 17.8 0.0 2.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase Caskin1-CID PF16600.5 RLN87309.1 - 1.4 9.5 7.2 0.25 11.9 0.9 2.4 2 0 0 2 2 2 0 Caskin1 CASK-interaction domain DUF155 PF02582.14 RLN87310.1 - 2.1e-49 168.0 0.1 2.8e-49 167.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 MS_channel PF00924.18 RLN87311.1 - 2.4e-07 30.5 0.6 5.7e-07 29.3 0.2 1.8 1 1 0 1 1 1 1 Mechanosensitive ion channel Trep_Strep PF09605.10 RLN87311.1 - 0.0039 17.2 3.0 0.0039 17.2 3.0 2.2 1 1 0 1 1 1 1 Hypothetical bacterial integral membrane protein (Trep_Strep) Exo_endo_phos PF03372.23 RLN87312.1 - 1e-07 31.8 0.1 1.7e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Dicty_CAR PF05462.11 RLN87312.1 - 9.1e-07 28.3 16.5 2e-06 27.2 16.5 1.5 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 RLN87312.1 - 7.4 5.8 11.4 16 4.7 11.4 1.6 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) LEM PF03020.15 RLN87313.1 - 0.0041 16.7 0.1 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 LEM domain CLZ PF16526.5 RLN87313.1 - 0.047 14.0 0.1 0.13 12.7 0.0 1.7 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TPR_12 PF13424.6 RLN87313.1 - 0.08 13.2 0.5 4.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat V_ATPase_I PF01496.19 RLN87314.1 - 1.7e-60 204.9 8.8 1.9e-60 204.8 8.8 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TraT PF05818.12 RLN87315.1 - 0.11 12.1 0.2 0.14 11.9 0.2 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Nkap_C PF06047.11 RLN87316.1 - 6.1e-21 74.5 3.8 7.7e-21 74.1 3.8 1.1 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain Ferric_reduct PF01794.19 RLN87318.1 - 0.044 13.9 1.5 4 7.6 0.1 3.0 2 0 0 2 2 2 0 Ferric reductase like transmembrane component PgaD PF13994.6 RLN87318.1 - 1.3 9.0 7.8 2 8.5 0.2 3.4 3 0 0 3 3 3 0 PgaD-like protein Atthog PF18800.1 RLN87319.1 - 0.018 14.9 0.1 0.035 14.0 0.1 1.4 1 0 0 1 1 1 0 Attenuator of Hedgehog Nkap_C PF06047.11 RLN87320.1 - 4.7e-47 158.3 1.7 6.6e-47 157.8 1.7 1.2 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain DUF4478 PF14793.6 RLN87320.1 - 0.088 12.7 0.1 1 9.2 0.1 2.0 2 0 0 2 2 2 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases HTH_Tnp_Tc5 PF03221.16 RLN87321.1 - 4.6e-07 29.8 0.0 8.3e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_Tnp_1 PF01527.20 RLN87321.1 - 1.3e-05 25.4 0.2 2.6e-05 24.5 0.2 1.5 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 RLN87321.1 - 0.066 13.4 0.1 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Dppa2_A PF14049.6 RLN87321.1 - 0.081 13.1 0.3 0.081 13.1 0.3 1.7 2 0 0 2 2 2 0 Dppa2/4 conserved region in higher vertebrates HTH_Tnp_IS630 PF01710.16 RLN87321.1 - 0.1 12.6 0.2 0.43 10.6 0.0 1.9 2 1 1 3 3 3 0 Transposase HTH_32 PF13565.6 RLN87321.1 - 0.12 13.0 0.5 1 10.1 0.1 2.3 3 0 0 3 3 3 0 Homeodomain-like domain HTH_23 PF13384.6 RLN87321.1 - 0.12 12.2 0.3 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain PCMT PF01135.19 RLN87322.1 - 4.4e-39 134.4 0.0 6.2e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 RLN87322.1 - 7.7e-10 38.8 0.0 1.9e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN87322.1 - 3.5e-08 34.0 0.0 7.5e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RLN87322.1 - 1.1e-06 28.3 0.0 1.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Drc1-Sld2 PF11719.8 RLN87322.1 - 1.3e-06 28.3 0.1 4.7e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 DNA replication and checkpoint protein Methyltransf_11 PF08241.12 RLN87322.1 - 1.3e-06 28.9 0.0 2.9e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN87322.1 - 0.00014 21.7 0.0 0.00025 20.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN87322.1 - 0.00015 22.5 0.0 0.0003 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN87322.1 - 0.00028 20.5 0.0 0.00045 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 RLN87322.1 - 0.0022 17.3 0.0 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 RLN87322.1 - 0.0027 17.1 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 RLN87322.1 - 0.041 13.9 0.2 0.098 12.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain GCD14 PF08704.10 RLN87322.1 - 0.074 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_4 PF02390.17 RLN87322.1 - 0.092 12.2 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_3 PF01596.17 RLN87322.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase DIOX_N PF14226.6 RLN87323.1 - 9.6e-16 58.6 0.3 5.2e-15 56.2 0.0 2.4 2 1 1 3 3 3 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 RLN87323.1 - 0.00017 22.0 0.2 0.0012 19.3 0.2 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LCM PF04072.14 RLN87324.1 - 8e-36 123.7 0.1 1.4e-35 122.9 0.0 1.4 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase LCM PF04072.14 RLN87325.1 - 1.9e-37 129.1 0.1 2.4e-37 128.7 0.1 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF3549 PF12069.8 RLN87325.1 - 0.076 12.1 0.8 0.11 11.5 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) Peptidase_C1 PF00112.23 RLN87326.1 - 1.1e-42 146.7 0.6 1.4e-42 146.2 0.6 1.2 1 0 0 1 1 1 1 Papain family cysteine protease UPF0179 PF03684.13 RLN87326.1 - 0.048 13.6 0.7 0.082 12.8 0.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0179) Peptidase_C1_2 PF03051.15 RLN87326.1 - 0.076 11.8 0.5 1.4 7.6 0.1 2.1 2 0 0 2 2 2 0 Peptidase C1-like family LCM PF04072.14 RLN87327.1 - 5.9e-39 134.0 0.0 7.6e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase NOA36 PF06524.12 RLN87328.1 - 1.1 8.5 10.5 1.6 8.0 10.5 1.2 1 0 0 1 1 1 0 NOA36 protein Merozoite_SPAM PF07133.11 RLN87328.1 - 1.2 9.1 16.5 1.7 8.6 16.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) TRAP_alpha PF03896.16 RLN87328.1 - 1.4 8.0 6.7 1.9 7.6 6.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DDRGK PF09756.9 RLN87329.1 - 0.093 12.3 9.2 0.12 11.9 9.2 1.1 1 0 0 1 1 1 0 DDRGK domain NOT2_3_5 PF04153.18 RLN87329.1 - 0.13 12.3 3.6 0.25 11.4 3.6 1.4 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family Vta1 PF04652.16 RLN87330.1 - 9.5e-30 103.5 0.1 5.4e-29 101.0 0.1 1.8 1 1 0 1 1 1 1 Vta1 like Metallophos PF00149.28 RLN87331.1 - 2.8e-34 119.4 0.1 3.5e-34 119.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RLN87331.1 - 5.3e-05 23.6 1.5 0.00016 22.0 0.2 2.2 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Anoctamin PF04547.12 RLN87332.1 - 1.3e-98 330.8 13.3 8.7e-98 328.1 13.3 1.9 1 1 0 1 1 1 1 Calcium-activated chloride channel Abhydrolase_9_N PF15420.6 RLN87332.1 - 0.046 13.7 0.3 0.14 12.2 0.3 1.8 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus FAT PF02259.23 RLN87333.1 - 3.1e-35 122.0 9.0 3.1e-35 122.0 9.0 2.6 3 0 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.27 RLN87333.1 - 5.9e-23 82.0 0.0 1.7e-22 80.5 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase GlcNAc PF11397.8 RLN87333.1 - 2.4e-13 50.3 0.0 2.4e-13 50.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase (GlcNAc) FATC PF02260.20 RLN87333.1 - 0.029 14.2 0.0 0.11 12.3 0.0 2.1 1 0 0 1 1 1 0 FATC domain DUF1160 PF06648.11 RLN87333.1 - 0.1 12.6 0.1 0.32 11.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) AAA_8 PF12780.7 RLN87334.1 - 2.3e-96 322.1 0.1 4.5e-96 321.2 0.0 1.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_lid_1 PF17857.1 RLN87334.1 - 1.4e-23 83.0 0.0 4.6e-23 81.3 0.0 1.9 2 0 0 2 2 2 1 AAA+ lid domain Pal1 PF08316.11 RLN87335.1 - 0.027 15.2 2.0 0.032 15.0 2.0 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein PKD_channel PF08016.12 RLN87336.1 - 1.2e-34 119.7 3.4 1.8e-34 119.2 3.4 1.2 1 0 0 1 1 1 1 Polycystin cation channel LapA_dom PF06305.11 RLN87336.1 - 1.6 8.6 4.2 2.8 7.8 0.6 2.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain PPR_long PF17177.4 RLN87337.1 - 1.9e-67 226.7 0.7 1.9e-67 226.7 0.7 1.8 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PRORP PF16953.5 RLN87337.1 - 1.7e-45 155.4 0.0 2.6e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 Protein-only RNase P PPR_2 PF13041.6 RLN87337.1 - 5.5e-14 52.1 0.1 0.00087 19.4 0.0 4.7 3 1 1 4 4 4 4 PPR repeat family PPR PF01535.20 RLN87337.1 - 4.6e-13 48.4 5.0 0.076 13.3 0.1 6.7 7 0 0 7 7 7 3 PPR repeat Elicitin PF00964.17 RLN87337.1 - 7.4e-13 48.4 5.6 7.4e-13 48.4 5.6 2.6 2 0 0 2 2 2 1 Elicitin PPR_3 PF13812.6 RLN87337.1 - 2.5e-10 40.3 0.1 0.00019 21.4 0.0 3.8 2 1 2 4 4 4 4 Pentatricopeptide repeat domain RNase_Zc3h12a PF11977.8 RLN87337.1 - 0.0021 17.9 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Hamartin PF04388.12 RLN87337.1 - 0.24 10.0 18.5 0.36 9.5 18.5 1.3 1 0 0 1 1 1 0 Hamartin protein U79_P34 PF03064.16 RLN87338.1 - 1.6 8.0 10.1 2.2 7.6 10.1 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Presenilin PF01080.17 RLN87338.1 - 1.9 7.2 3.6 2.1 7.0 3.6 1.0 1 0 0 1 1 1 0 Presenilin ABC2_membrane_3 PF12698.7 RLN87340.1 - 1.9e-38 132.4 18.0 3.4e-38 131.6 18.0 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 RLN87340.1 - 3.5e-11 43.8 0.3 9.9e-07 29.3 0.2 2.5 1 1 1 2 2 2 2 ABC transporter ASH PF15780.5 RLN87341.1 - 1.7e-53 178.8 22.7 5.3e-07 29.8 0.0 20.0 22 1 1 23 23 23 12 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 RLN87341.1 - 4.9e-23 81.1 1.8 0.11 12.4 0.0 14.4 15 0 0 15 15 15 6 MSP (Major sperm protein) domain PapD-like PF14874.6 RLN87341.1 - 1.4e-19 70.1 0.2 0.05 13.8 0.0 10.3 10 0 0 10 10 10 5 Flagellar-associated PapD-like TMEM131_like PF12371.8 RLN87341.1 - 7.1e-13 48.6 6.7 0.047 14.0 0.0 11.8 12 0 0 12 12 12 2 Transmembrane protein 131-like DUF1573 PF07610.11 RLN87341.1 - 8.4e-13 48.2 8.6 0.12 12.4 0.0 11.6 15 1 0 15 15 15 3 Protein of unknown function (DUF1573) MYCBPAP PF14646.6 RLN87341.1 - 0.00047 19.2 8.2 16 4.3 0.0 8.5 11 0 0 11 11 11 1 MYCBP-associated protein family Hydin_ADK PF17213.3 RLN87341.1 - 0.0055 17.0 0.0 0.024 14.9 0.0 2.1 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain fn3_6 PF17766.1 RLN87341.1 - 0.019 15.1 0.4 3 8.1 0.0 4.9 4 1 1 5 5 5 0 Fibronectin type-III domain Peptidase_M24 PF00557.24 RLN87342.1 - 3.2e-45 154.4 0.0 4.2e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF1279 PF06916.13 RLN87342.1 - 4.2e-08 33.6 0.0 6.4e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Prenyltrans PF00432.21 RLN87343.1 - 2.4e-15 56.0 18.8 4.5e-07 29.5 0.7 5.1 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat RICTOR_N PF14664.6 RLN87343.1 - 0.024 13.6 0.1 0.032 13.2 0.1 1.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term ASH PF15780.5 RLN87347.1 - 2.9e-16 59.5 14.4 0.00074 19.7 0.1 8.6 8 1 0 9 9 9 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 RLN87347.1 - 4.3e-06 26.9 0.0 0.067 13.5 0.0 4.3 4 0 0 4 4 4 1 Transmembrane protein 131-like Motile_Sperm PF00635.26 RLN87347.1 - 0.00038 20.3 0.7 0.013 15.3 0.0 3.4 3 0 0 3 3 3 1 MSP (Major sperm protein) domain MYCBPAP PF14646.6 RLN87347.1 - 0.00046 19.3 0.0 0.00093 18.2 0.0 1.5 1 0 0 1 1 1 1 MYCBP-associated protein family fn3_5 PF06280.12 RLN87347.1 - 0.019 15.6 1.6 2.4 8.9 0.0 4.6 4 2 0 4 4 4 0 Fn3-like domain PapD-like PF14874.6 RLN87347.1 - 0.094 12.9 0.1 0.54 10.5 0.0 2.3 2 0 0 2 2 2 0 Flagellar-associated PapD-like Phage_integrase PF00589.22 RLN87348.1 - 0.0019 18.0 0.1 0.0038 17.0 0.0 1.5 2 0 0 2 2 2 1 Phage integrase family CENP-F_leu_zip PF10473.9 RLN87349.1 - 0.0025 17.8 11.6 0.28 11.2 0.2 2.5 2 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4472 PF14739.6 RLN87349.1 - 0.22 12.3 0.3 0.22 12.3 0.3 3.7 3 1 2 5 5 5 0 Domain of unknown function (DUF4472) PPP4R2 PF09184.11 RLN87349.1 - 2.9 7.4 7.7 4.4 6.8 7.7 1.3 1 0 0 1 1 1 0 PPP4R2 DUF3450 PF11932.8 RLN87349.1 - 4.9 6.4 24.0 0.65 9.2 5.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Pex14_N PF04695.13 RLN87350.1 - 0.019 15.6 8.5 0.025 15.2 8.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EVI2A PF05399.11 RLN87350.1 - 0.034 13.8 1.8 0.042 13.4 1.8 1.1 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Med13_C PF06333.12 RLN87350.1 - 0.096 11.9 7.0 0.11 11.7 7.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain PRCC PF10253.9 RLN87350.1 - 0.4 11.4 6.2 0.5 11.1 6.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting KAR9 PF08580.10 RLN87350.1 - 6.7 5.1 8.0 8.3 4.8 8.0 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DAO PF01266.24 RLN87351.1 - 5.9e-40 137.9 0.0 6.7e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 RLN87351.1 - 0.0019 17.7 0.0 0.0094 15.3 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 RLN87351.1 - 0.0081 15.3 0.2 0.0081 15.3 0.2 1.4 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 RLN87351.1 - 0.054 12.6 2.1 1.2 8.1 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 RLN87351.1 - 0.11 12.8 3.3 0.2 11.9 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain IBR PF01485.21 RLN87353.1 - 4.6e-11 42.8 34.4 5.2e-08 33.0 5.6 3.5 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 RLN87353.1 - 1.5e-06 27.9 2.7 1.5e-06 27.9 2.7 4.3 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN87353.1 - 2.1e-06 27.4 2.4 2.1e-06 27.4 2.4 4.3 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN87353.1 - 4.9e-06 26.8 2.6 4.9e-06 26.8 2.6 4.1 4 1 1 5 5 5 1 Ring finger domain zf-RING_UBOX PF13445.6 RLN87353.1 - 1.2e-05 25.2 4.2 1.2e-05 25.2 4.2 2.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN87353.1 - 9.4e-05 22.3 4.9 9.4e-05 22.3 4.9 4.7 4 1 1 5 5 5 1 zinc-RING finger domain GFO_IDH_MocA PF01408.22 RLN87354.1 - 1.4e-06 29.1 0.0 2.8e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 RLN87354.1 - 1.7e-05 24.8 0.0 3.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Gp_dh_N PF00044.24 RLN87354.1 - 0.061 13.7 0.0 0.21 11.9 0.0 1.9 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain RRM_1 PF00076.22 RLN87357.1 - 7.8e-30 102.5 0.0 3e-14 52.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN87357.1 - 1.5e-06 28.2 0.0 0.014 15.5 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 RLN87357.1 - 0.00036 20.5 0.0 0.75 9.8 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Hamartin PF04388.12 RLN87357.1 - 0.28 9.8 5.4 0.3 9.7 5.4 1.1 1 0 0 1 1 1 0 Hamartin protein HGTP_anticodon2 PF12745.7 RLN87357.1 - 7.7 5.9 10.1 3.5 7.1 6.4 2.0 1 1 1 2 2 2 0 Anticodon binding domain of tRNAs RTC PF01137.21 RLN87358.1 - 3.2e-63 212.9 1.5 4.8e-63 212.3 1.5 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase TatD_DNase PF01026.21 RLN87358.1 - 1e-60 205.3 0.0 2.2e-60 204.2 0.0 1.6 2 0 0 2 2 2 1 TatD related DNase RTC_insert PF05189.13 RLN87358.1 - 0.078 13.5 0.8 0.22 12.1 0.8 1.8 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain Kelch_3 PF13415.6 RLN87359.1 - 1.7e-28 98.3 14.4 4.9e-06 26.7 0.0 7.4 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN87359.1 - 1.1e-26 92.4 3.4 0.00023 21.0 0.0 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 RLN87359.1 - 1.9e-24 85.0 1.7 7e-08 32.5 0.0 5.9 4 1 2 6 6 6 5 Kelch motif Kelch_4 PF13418.6 RLN87359.1 - 1.2e-22 79.6 6.2 1.4e-06 28.2 0.1 5.6 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 RLN87359.1 - 1.2e-20 72.6 6.6 9.1e-06 25.5 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 RLN87359.1 - 1.4e-20 72.6 0.6 0.00015 21.3 0.0 6.0 6 0 0 6 6 6 3 Kelch motif GST_C_2 PF13410.6 RLN87359.1 - 9.9e-06 25.5 1.5 2.7e-05 24.1 1.5 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RLN87359.1 - 1.2e-05 25.4 0.3 3e-05 24.1 0.3 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RLN87359.1 - 0.0012 19.0 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 RLN87359.1 - 0.0048 16.7 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_2b PF00587.25 RLN87360.1 - 1.1e-39 136.3 0.0 1.8e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 RLN87360.1 - 5.6e-18 64.9 0.1 1.5e-17 63.5 0.1 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 RLN87360.1 - 9e-09 35.3 0.0 1.7e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain HsdM_N PF12161.8 RLN87360.1 - 0.096 13.3 0.0 3.8 8.1 0.0 2.6 2 0 0 2 2 2 0 HsdM N-terminal domain DUF1192 PF06698.11 RLN87360.1 - 2.2 8.4 5.4 18 5.5 4.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) CxxCxxCC PF03692.15 RLN87361.1 - 2e-08 34.8 2.4 1.3e-07 32.2 2.4 2.1 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain WD40 PF00400.32 RLN87362.1 - 0.064 14.1 0.1 0.26 12.2 0.1 2.1 1 0 0 1 1 1 0 WD domain, G-beta repeat TMF_DNA_bd PF12329.8 RLN87362.1 - 3 7.9 9.1 0.65 10.0 3.9 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SKG6 PF08693.10 RLN87363.1 - 0.0012 18.2 1.3 0.0024 17.2 1.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain PTP_tm PF18861.1 RLN87363.1 - 0.004 17.2 0.0 0.0089 16.0 0.0 1.6 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Mid2 PF04478.12 RLN87363.1 - 0.004 17.0 0.0 0.019 14.8 0.0 2.1 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor MtrF PF09472.10 RLN87363.1 - 0.02 14.2 3.2 0.04 13.3 3.2 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) EphA2_TM PF14575.6 RLN87363.1 - 0.1 13.5 0.0 0.23 12.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Trp_oprn_chp PF09534.10 RLN87363.1 - 0.11 12.3 0.9 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SIT PF15330.6 RLN87363.1 - 0.19 12.2 0.0 2.4 8.6 0.0 2.5 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT TMEM154 PF15102.6 RLN87363.1 - 1.3 8.9 0.0 1.3 8.9 0.0 3.6 3 1 1 4 4 4 0 TMEM154 protein family MFS_1 PF07690.16 RLN87364.1 - 2.1e-36 125.6 77.3 1.1e-19 70.5 33.4 3.3 1 1 2 3 3 3 3 Major Facilitator Superfamily Nodulin-like PF06813.13 RLN87364.1 - 1e-08 35.0 27.1 2.2e-05 24.1 4.5 3.2 3 1 0 3 3 3 2 Nodulin-like Podoplanin PF05808.11 RLN87365.1 - 2.2 8.4 4.4 7.2 6.7 4.4 2.0 1 1 0 1 1 1 0 Podoplanin DUF2614 PF11023.8 RLN87366.1 - 2.5 8.2 5.2 2 8.6 1.2 2.4 2 0 0 2 2 2 0 Zinc-ribbon containing domain DUF2070 PF09843.9 RLN87366.1 - 3 6.0 8.9 3.6 5.8 8.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) GCP_C_terminal PF04130.13 RLN87367.1 - 1.1e-08 34.9 0.0 3.2e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Mitochondr_Som1 PF11093.8 RLN87367.1 - 0.13 12.2 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial export protein Som1 Dimer_Tnp_hAT PF05699.14 RLN87369.1 - 5.2e-19 67.8 0.1 8.7e-19 67.1 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Rhabdo_NV PF02484.15 RLN87369.1 - 0.061 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Rhabdovirus Non-virion protein Endonuc-FokI_C PF09254.11 RLN87369.1 - 0.076 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal cNMP_binding PF00027.29 RLN87370.1 - 1.8e-12 47.2 0.0 0.00072 19.6 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain M16C_assoc PF08367.11 RLN87370.1 - 0.14 11.3 0.1 8.8 5.4 0.0 2.3 2 0 0 2 2 2 0 Peptidase M16C associated Hist_deacetyl PF00850.19 RLN87371.1 - 4e-76 256.4 0.0 5.4e-76 256.0 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ANAPC3 PF12895.7 RLN87372.1 - 5.9e-08 32.8 30.5 0.00026 21.2 8.4 6.4 5 2 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 RLN87372.1 - 7.2e-07 29.6 26.3 1.5e-06 28.6 0.2 6.4 6 2 1 7 7 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN87372.1 - 8.3e-06 25.5 28.4 0.43 10.8 0.4 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 RLN87372.1 - 0.00013 22.3 20.2 0.19 12.4 0.1 7.8 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN87372.1 - 0.00029 21.1 24.5 0.014 15.7 3.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN87372.1 - 0.00086 19.1 7.7 1.1 9.3 0.1 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat YfiO PF13525.6 RLN87372.1 - 0.0013 18.5 2.1 2.2 7.9 0.9 3.6 2 1 1 3 3 3 2 Outer membrane lipoprotein HrpB1_HrpK PF09613.10 RLN87372.1 - 0.0017 18.0 7.1 5 6.8 0.2 4.6 3 2 1 4 4 4 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_16 PF13432.6 RLN87372.1 - 0.0019 18.8 24.8 0.13 12.9 0.9 6.7 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN87372.1 - 0.0072 16.3 12.8 0.091 12.8 0.1 6.4 8 0 0 8 8 8 1 Tetratricopeptide repeat Rotavirus_VP3 PF06929.11 RLN87372.1 - 0.07 11.3 0.1 0.1 10.8 0.1 1.1 1 0 0 1 1 1 0 Rotavirus VP3 protein TPR_8 PF13181.6 RLN87372.1 - 2.6 8.5 10.3 30 5.2 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN87372.1 - 4.6 7.4 14.2 0.27 11.3 0.7 4.6 5 1 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 RLN87372.1 - 5 8.2 23.9 5 8.2 0.1 7.6 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN87372.1 - 7.2 6.6 15.1 9.2 6.3 0.2 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Cwf_Cwc_15 PF04889.12 RLN87373.1 - 2.3e-52 178.2 36.0 2e-48 165.3 28.9 2.1 1 1 1 2 2 2 2 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 RLN87373.1 - 0.17 10.1 16.9 0.2 9.9 16.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid_p PF12226.8 RLN87373.1 - 6.7 5.8 12.7 8 5.5 12.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein rRNA_processing PF08524.11 RLN87373.1 - 9.4 6.3 21.1 71 3.4 18.8 2.1 1 1 1 2 2 2 0 rRNA processing Rad60-SLD PF11976.8 RLN87374.1 - 2.9e-14 52.6 0.1 6.3e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 RLN87374.1 - 0.017 14.8 0.0 0.42 10.4 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin family PRP1_N PF06424.12 RLN87374.1 - 1.7 9.0 7.7 3.1 8.2 7.7 1.4 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal FAM219A PF15260.6 RLN87374.1 - 5.2 7.4 7.1 2.9 8.3 3.6 2.2 1 1 1 2 2 2 0 Protein family FAM219A Far-17a_AIG1 PF04750.14 RLN87375.1 - 3.7e-05 23.1 9.3 3.7e-05 23.1 9.3 1.8 2 0 0 2 2 2 1 FAR-17a/AIG1-like protein Pept_tRNA_hydro PF01195.19 RLN87376.1 - 3.3e-43 147.6 0.0 5.3e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase tRNA_edit PF04073.15 RLN87376.1 - 0.0043 17.1 0.0 0.0081 16.2 0.0 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain DAHP_synth_1 PF00793.20 RLN87377.1 - 1.2e-34 119.5 0.0 5.2e-27 94.4 0.0 2.1 2 0 0 2 2 2 2 DAHP synthetase I family SLAC1 PF03595.17 RLN87377.1 - 0.025 13.8 0.2 0.046 13.0 0.2 1.3 1 0 0 1 1 1 0 Voltage-dependent anion channel MORN PF02493.20 RLN87378.1 - 4.1e-20 70.4 20.4 4.6e-06 26.2 0.2 7.2 8 0 0 8 8 8 5 MORN repeat DUF4982 PF16355.5 RLN87378.1 - 0.16 11.9 2.0 11 6.0 0.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4982) Pro_isomerase PF00160.21 RLN87379.1 - 1.5e-46 158.5 0.1 1.5e-46 158.5 0.1 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.9 RLN87379.1 - 0.00021 21.0 19.0 0.0004 20.1 19.0 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein YL1 PF05764.13 RLN87379.1 - 0.022 14.9 23.0 0.028 14.5 23.0 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Spem1 PF15670.5 RLN87379.1 - 0.32 10.5 5.5 0.44 10.1 5.5 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 NARP1 PF12569.8 RLN87379.1 - 1 8.2 20.1 1.4 7.8 20.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Dsh_C PF12316.8 RLN87379.1 - 1.1 9.6 5.9 1.6 9.1 5.9 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal eIF3_subunit PF08597.10 RLN87379.1 - 1.1 9.1 24.5 1.6 8.6 24.5 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CDC45 PF02724.14 RLN87379.1 - 1.2 7.4 16.1 1.6 6.9 16.1 1.2 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 RLN87379.1 - 1.2 9.2 24.3 1.7 8.7 24.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 PBP_sp32 PF07222.12 RLN87379.1 - 1.6 8.1 8.8 2.3 7.6 8.8 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Zip PF02535.22 RLN87379.1 - 2 7.5 7.2 2.5 7.2 7.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4407 PF14362.6 RLN87379.1 - 2.1 7.6 6.5 2.7 7.3 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Neur_chan_memb PF02932.16 RLN87379.1 - 3 7.9 4.5 3.8 7.5 4.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1764 PF08576.10 RLN87379.1 - 3.5 8.6 15.6 7.4 7.5 15.6 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Mucin PF01456.17 RLN87380.1 - 0.095 12.7 21.4 0.15 12.0 21.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein GST_C_3 PF14497.6 RLN87382.1 - 3.8e-14 52.7 0.0 8.1e-12 45.2 0.0 2.2 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RLN87382.1 - 2.4e-12 47.0 0.0 1.3e-06 28.6 0.0 3.4 3 2 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN87382.1 - 0.00053 20.0 0.0 0.0092 16.0 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RLN87382.1 - 0.0054 16.9 0.0 0.018 15.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RLN87382.1 - 0.007 16.8 0.0 4.8 7.7 0.0 2.8 2 1 0 2 2 2 2 Glutathione S-transferase, N-terminal domain zf-Nse PF11789.8 RLN87383.1 - 1.7e-11 43.8 0.5 3.3e-11 42.8 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 RLN87383.1 - 0.00067 19.4 0.5 0.0021 17.8 0.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN87383.1 - 0.0016 18.5 0.4 0.0028 17.6 0.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger BORCS7 PF16088.5 RLN87383.1 - 0.0026 18.0 0.2 0.0054 17.0 0.2 1.4 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 7 ISG65-75 PF11727.8 RLN87383.1 - 0.0035 16.6 0.6 0.0052 16.1 0.6 1.3 1 0 0 1 1 1 1 Invariant surface glycoprotein zf-RING_2 PF13639.6 RLN87383.1 - 0.027 14.8 0.2 0.057 13.8 0.2 1.5 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 RLN87383.1 - 0.031 14.6 0.2 0.15 12.3 0.1 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-MIZ PF02891.20 RLN87383.1 - 0.038 13.8 0.4 0.038 13.8 0.4 1.7 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Ribosomal_L35Ae PF01247.18 RLN87384.1 - 2.4e-16 59.7 0.2 2.7e-16 59.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae HA2 PF04408.23 RLN87385.1 - 6.8e-22 77.8 0.0 1.5e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RLN87385.1 - 1.8e-17 63.5 0.0 3.4e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 RLN87385.1 - 5e-15 55.8 0.0 1.3e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RLN87385.1 - 1.4e-08 34.7 0.3 3.9e-08 33.3 0.3 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RLN87385.1 - 0.00013 22.2 0.1 0.00055 20.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 RLN87385.1 - 0.00037 20.5 0.1 0.00097 19.1 0.1 1.7 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.15 RLN87385.1 - 0.0027 17.7 0.0 0.047 13.7 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 RLN87385.1 - 0.0047 16.7 0.1 0.0094 15.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RLN87385.1 - 0.0053 17.1 0.1 0.012 16.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 RLN87385.1 - 0.0098 15.0 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 RLN87385.1 - 0.012 16.1 0.1 0.8 10.2 0.1 3.1 2 1 1 3 3 3 0 ABC transporter AAA_7 PF12775.7 RLN87385.1 - 0.056 13.0 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 RLN87385.1 - 0.07 12.6 0.0 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein cobW PF02492.19 RLN87385.1 - 0.083 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Erf4 PF10256.9 RLN87386.1 - 1.4e-05 25.2 0.0 2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family MULE PF10551.9 RLN87387.1 - 0.00059 20.2 0.0 0.0012 19.3 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain TPR_2 PF07719.17 RLN87388.1 - 1.2e-41 137.5 0.8 0.00032 20.6 0.0 10.0 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_1 PF00515.28 RLN87388.1 - 2.5e-36 122.0 0.2 0.00012 21.7 0.0 8.5 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 RLN87388.1 - 9.5e-33 109.7 0.4 0.0017 18.4 0.0 8.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.6 RLN87388.1 - 5.5e-29 99.6 0.2 1.5e-08 34.2 0.0 8.0 6 2 2 8 8 7 6 TPR repeat TPR_12 PF13424.6 RLN87388.1 - 1.2e-20 73.6 7.7 0.00021 21.5 0.1 7.2 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 RLN87388.1 - 3e-20 71.1 5.8 0.002 18.4 0.0 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 RLN87388.1 - 9.9e-20 70.9 0.4 0.00085 19.9 0.0 6.1 5 1 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 RLN87388.1 - 8e-19 66.7 2.0 0.0023 18.6 0.0 9.0 4 2 6 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN87388.1 - 1.4e-17 62.3 0.3 0.075 13.1 0.0 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN87388.1 - 1.4e-16 60.4 4.7 0.0076 16.5 0.2 6.5 4 2 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 RLN87388.1 - 4.6e-16 59.1 0.9 0.023 15.2 0.0 7.0 5 3 2 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 RLN87388.1 - 5e-14 52.2 0.5 0.0088 16.2 0.0 6.3 2 1 6 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 RLN87388.1 - 1.9e-11 43.8 1.7 0.25 12.1 0.0 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN87388.1 - 1.9e-08 33.9 8.0 1.4 8.9 0.0 7.6 8 0 0 8 8 7 1 Tetratricopeptide repeat NARP1 PF12569.8 RLN87388.1 - 2e-07 30.3 0.1 0.0027 16.7 0.2 3.2 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 RLN87388.1 - 6.5e-06 25.6 0.1 0.57 9.3 0.0 4.5 1 1 2 4 4 4 3 Tetratricopeptide repeat TPR_3 PF07720.12 RLN87388.1 - 0.00019 21.4 1.4 17 5.5 0.1 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 RLN87388.1 - 0.0015 18.0 0.1 0.27 10.6 0.0 3.0 2 1 1 3 3 3 1 MalT-like TPR region PknG_TPR PF16918.5 RLN87388.1 - 0.0021 16.8 0.1 0.31 9.7 0.0 2.3 2 0 0 2 2 2 1 Protein kinase G tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN87388.1 - 0.0029 17.6 0.2 31 4.7 0.0 5.0 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 RLN87388.1 - 0.012 16.1 2.0 0.035 14.5 0.1 2.8 4 0 0 4 4 3 0 Bacterial transcriptional activator domain Wzy_C_2 PF11846.8 RLN87388.1 - 0.032 14.1 0.1 1.7 8.5 0.0 3.4 4 0 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal ANAPC5 PF12862.7 RLN87388.1 - 0.098 12.7 2.3 6.2 7.0 0.1 3.9 3 2 0 3 3 3 0 Anaphase-promoting complex subunit 5 DUF3808 PF10300.9 RLN87388.1 - 0.14 10.8 2.8 0.39 9.4 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3808) Aldo_ket_red PF00248.21 RLN87389.1 - 2.1e-68 230.7 0.0 2.4e-68 230.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RPAP3_C PF13877.6 RLN87390.1 - 7e-17 61.8 0.0 1.5e-16 60.6 0.0 1.5 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 Tetrabrachion PF11401.8 RLN87390.1 - 0.012 15.6 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Tetrabrachion SnoaL_3 PF13474.6 RLN87390.1 - 0.027 14.7 0.0 0.034 14.4 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain CGI-121 PF08617.10 RLN87391.1 - 2.3e-30 105.8 0.0 2.5e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Transketolase_N PF00456.21 RLN87392.1 - 1.7e-43 148.9 0.0 1.9e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Terpene_synth PF01397.21 RLN87392.1 - 0.042 13.5 0.0 0.051 13.3 0.0 1.1 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain SWIM PF04434.17 RLN87393.1 - 0.065 12.9 0.6 0.16 11.7 0.6 1.6 1 0 0 1 1 1 0 SWIM zinc finger Muted PF14942.6 RLN87394.1 - 0.023 15.1 0.6 0.023 15.1 0.6 1.8 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein CRIC_ras_sig PF10534.9 RLN87394.1 - 0.044 14.0 0.5 4.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras VBS PF08913.10 RLN87394.1 - 0.056 13.9 0.9 0.56 10.7 0.2 2.0 2 0 0 2 2 2 0 Vinculin Binding Site URO-D PF01208.17 RLN87394.1 - 0.13 11.4 0.3 3.8 6.6 0.0 2.0 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) Dynamin_N PF00350.23 RLN87395.1 - 1.5e-07 31.6 0.3 6.4e-07 29.6 0.3 1.9 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 RLN87395.1 - 1.9e-06 28.0 0.0 3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 RLN87395.1 - 0.012 15.8 0.1 0.021 15.0 0.1 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 RLN87395.1 - 0.043 13.6 0.1 0.26 11.1 0.0 2.1 1 1 1 2 2 2 0 P-loop containing region of AAA domain IIGP PF05049.13 RLN87395.1 - 0.085 11.9 0.0 0.18 10.8 0.0 1.5 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 RLN87395.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AIG1 PF04548.16 RLN87395.1 - 0.14 11.5 0.2 11 5.3 0.3 2.1 2 0 0 2 2 2 0 AIG1 family Levi_coat PF01819.17 RLN87397.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Levivirus coat protein NOG1_N PF17835.1 RLN87398.1 - 0.0025 17.8 0.0 0.0032 17.4 0.0 1.1 1 0 0 1 1 1 1 NOG1 N-terminal helical domain JmjC PF02373.22 RLN87400.1 - 1.1e-42 145.1 0.4 2.1e-42 144.2 0.4 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase PLU-1 PF08429.11 RLN87400.1 - 7.9e-16 58.1 10.5 7.3e-09 35.2 0.2 4.3 4 2 1 5 5 5 2 PLU-1-like protein zf-C5HC2 PF02928.16 RLN87400.1 - 5.8e-14 52.2 7.4 5.8e-14 52.2 7.4 2.8 2 0 0 2 2 2 1 C5HC2 zinc finger PHD PF00628.29 RLN87400.1 - 2.3e-11 43.4 35.2 8.3e-08 32.0 9.0 3.4 3 0 0 3 3 3 2 PHD-finger Cob_adeno_trans PF01923.18 RLN87400.1 - 0.15 12.2 12.8 0.96 9.6 3.9 3.0 3 0 0 3 3 3 0 Cobalamin adenosyltransferase CK2S PF15011.6 RLN87400.1 - 1.1 9.1 6.2 3.5 7.5 0.0 4.1 3 1 1 4 4 4 0 Casein Kinase 2 substrate PHD_4 PF16866.5 RLN87400.1 - 1.3 9.2 16.8 0.67 10.1 3.2 2.9 1 1 1 2 2 2 0 PHD-finger PDDEXK_2 PF12784.7 RLN87402.1 - 0.037 13.6 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease family transposase PX PF00787.24 RLN87402.1 - 0.073 13.1 0.0 0.23 11.5 0.0 1.8 1 1 0 1 1 1 0 PX domain TPD PF14811.6 RLN87403.1 - 1.4e-46 157.8 0.0 3.9e-46 156.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function TPD sequence-motif PX PF00787.24 RLN87403.1 - 0.097 12.7 2.8 0.25 11.4 0.9 2.4 2 1 0 2 2 2 0 PX domain HSP70 PF00012.20 RLN87406.1 - 4.1e-222 738.6 4.5 4.9e-222 738.4 4.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN87406.1 - 1.3e-15 57.1 0.0 2e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 RLN87406.1 - 0.0018 18.0 0.0 0.0046 16.7 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 RLN87406.1 - 0.012 14.6 0.2 0.085 11.8 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 RLN87406.1 - 0.033 13.5 0.1 0.081 12.2 0.1 1.7 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Syntaxin-6_N PF09177.11 RLN87407.1 - 5.6e-06 26.8 6.2 5.9e-05 23.6 0.3 2.6 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 RLN87407.1 - 0.00058 19.8 2.0 0.00094 19.1 0.5 2.2 3 0 0 3 3 2 1 SNARE domain DUF5082 PF16888.5 RLN87407.1 - 0.003 17.8 2.7 0.003 17.8 2.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) P22_AR_C PF10548.9 RLN87407.1 - 0.014 15.6 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 P22AR C-terminal domain ATG16 PF08614.11 RLN87407.1 - 0.02 15.1 11.6 0.018 15.3 10.1 1.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) BLOC1S3 PF15753.5 RLN87407.1 - 0.033 14.3 5.7 0.041 14.0 5.7 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Hormone_1 PF00103.20 RLN87407.1 - 0.082 12.6 2.2 0.13 12.0 1.6 1.5 1 1 1 2 2 2 0 Somatotropin hormone family PhaP_Bmeg PF09602.10 RLN87407.1 - 0.15 12.0 5.1 0.075 13.0 2.3 1.9 2 1 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Cytochrom_C552 PF02335.15 RLN87407.1 - 0.15 10.9 2.4 0.15 10.9 1.0 1.4 1 1 0 1 1 1 0 Cytochrome c552 DUF4208 PF13907.6 RLN87407.1 - 0.39 11.2 4.7 1 9.8 0.1 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4208) SKA1 PF07160.12 RLN87407.1 - 0.57 10.0 9.2 0.15 11.9 1.5 2.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF948 PF06103.11 RLN87407.1 - 1.1 9.5 3.6 0.55 10.5 0.8 2.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) XhlA PF10779.9 RLN87407.1 - 2.1 8.6 5.1 20 5.5 0.3 2.8 3 0 0 3 3 3 0 Haemolysin XhlA NPV_P10 PF05531.12 RLN87407.1 - 2.3 8.7 6.7 3.1 8.3 1.8 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 RLN87407.1 - 3.4 8.4 14.0 9.9 6.9 0.9 3.8 2 1 2 4 4 4 0 SlyX DUF16 PF01519.16 RLN87407.1 - 4.8 7.7 10.0 14 6.2 7.3 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 FAM76 PF16046.5 RLN87407.1 - 8.7 5.6 9.5 11 5.2 9.5 1.2 1 0 0 1 1 1 0 FAM76 protein zinc_ribbon_9 PF14369.6 RLN87409.1 - 0.093 13.0 0.7 0.32 11.3 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon PX PF00787.24 RLN87409.1 - 0.26 11.3 1.8 1.4 8.9 1.8 2.1 1 1 0 1 1 1 0 PX domain DDE_Tnp_IS240 PF13610.6 RLN87410.1 - 0.026 14.7 0.1 0.072 13.3 0.0 1.7 2 1 0 2 2 2 0 DDE domain PX PF00787.24 RLN87410.1 - 0.03 14.3 0.1 0.064 13.3 0.1 1.6 1 1 0 1 1 1 0 PX domain Pkinase PF00069.25 RLN87412.1 - 1.9e-61 207.8 0.0 4.5e-61 206.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN87412.1 - 1.3e-44 152.4 0.0 2.5e-44 151.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RhoGAP PF00620.27 RLN87412.1 - 1.1e-22 80.5 0.0 2.4e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain Pkinase_fungal PF17667.1 RLN87412.1 - 0.00037 19.4 0.6 0.00098 18.0 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase eIF3_subunit PF08597.10 RLN87412.1 - 0.75 9.7 4.5 3.9 7.3 0.0 3.0 3 0 0 3 3 3 0 Translation initiation factor eIF3 subunit Sec15 PF04091.12 RLN87413.1 - 5.8e-25 88.4 0.0 1e-24 87.5 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Vps51 PF08700.11 RLN87413.1 - 0.0061 16.6 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 HSP70 PF00012.20 RLN87415.1 - 8.9e-217 721.0 1.9 1e-216 720.8 1.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN87415.1 - 1.5e-15 56.8 0.0 2.5e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.18 RLN87415.1 - 0.0061 15.9 0.1 0.016 14.5 0.1 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase WD40 PF00400.32 RLN87416.1 - 4.7e-17 62.1 17.8 0.00012 22.8 0.1 8.8 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN87416.1 - 1.6e-08 34.7 2.3 0.041 14.2 0.2 4.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN87416.1 - 0.019 13.6 0.1 0.061 12.0 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RLN87416.1 - 0.033 13.2 0.0 2.5 7.0 0.1 2.4 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_2 PF07724.14 RLN87417.1 - 1.8e-44 151.8 0.0 4e-44 150.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 RLN87417.1 - 2.7e-14 53.7 0.0 5.1e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 RLN87417.1 - 1.8e-12 47.1 0.1 3.9e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.6 RLN87417.1 - 3.7e-05 24.0 0.2 0.00032 21.0 0.2 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 RLN87417.1 - 4.9e-05 23.1 0.2 0.005 16.6 0.0 2.8 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RLN87417.1 - 0.00016 21.7 0.2 0.00085 19.3 0.2 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 RLN87417.1 - 0.0004 19.9 0.0 0.00093 18.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region MCM PF00493.23 RLN87417.1 - 0.00054 19.1 0.2 0.0013 17.9 0.1 1.6 2 0 0 2 2 2 1 MCM P-loop domain Sigma54_activat PF00158.26 RLN87417.1 - 0.0014 18.4 0.0 0.007 16.1 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 RLN87417.1 - 0.0037 17.4 0.0 0.0097 16.0 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 RLN87417.1 - 0.0044 16.4 0.0 0.019 14.4 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 RLN87417.1 - 0.0046 17.0 0.0 0.0084 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RLN87417.1 - 0.0051 17.0 0.1 0.017 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 RLN87417.1 - 0.011 16.2 0.0 0.027 15.0 0.0 1.7 1 1 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 RLN87417.1 - 0.015 15.0 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 RLN87417.1 - 0.015 15.6 0.2 0.11 12.9 0.1 2.2 1 1 2 3 3 3 0 AAA ATPase domain TsaE PF02367.17 RLN87417.1 - 0.022 14.8 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IPT PF01745.16 RLN87417.1 - 0.037 13.4 0.2 0.077 12.4 0.2 1.4 1 0 0 1 1 1 0 Isopentenyl transferase PhoH PF02562.16 RLN87417.1 - 0.044 13.2 0.1 0.12 11.8 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 RLN87417.1 - 0.088 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 RLN87417.1 - 0.094 11.6 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.6 RLN87417.1 - 0.097 13.2 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 RLN87417.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 RLN87417.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 RLN87417.1 - 0.18 12.2 0.0 0.4 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DEAD PF00270.29 RLN87417.1 - 0.18 11.5 0.4 0.69 9.7 0.2 1.9 1 1 1 2 2 2 0 DEAD/DEAH box helicase Calpain_inhib PF00748.19 RLN87417.1 - 5.6 7.5 8.2 16 6.0 8.2 1.7 1 0 0 1 1 1 0 Calpain inhibitor Ammonium_transp PF00909.21 RLN87418.1 - 4.4e-69 233.1 10.4 5.4e-69 232.8 10.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family RIB43A PF05914.12 RLN87419.1 - 9e-20 70.7 8.1 1e-19 70.6 8.1 1.0 1 0 0 1 1 1 1 RIB43A DUF2313 PF10076.9 RLN87419.1 - 0.0057 16.5 0.2 0.0068 16.3 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2313) VASt PF16016.5 RLN87421.1 - 2.9e-31 109.0 0.1 5e-31 108.2 0.1 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain Macoilin PF09726.9 RLN87421.1 - 0.31 9.5 6.9 0.32 9.5 4.4 2.0 2 0 0 2 2 2 0 Macoilin family Ndc1_Nup PF09531.10 RLN87421.1 - 3.5 6.2 11.4 5.1 5.7 0.0 2.5 3 0 0 3 3 3 0 Nucleoporin protein Ndc1-Nup SR-25 PF10500.9 RLN87422.1 - 5.6e-08 32.7 48.6 5.6e-08 32.7 48.6 2.3 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein DRY_EERY PF09750.9 RLN87423.1 - 9.1e-12 45.4 0.0 9.1e-12 45.4 0.0 2.2 3 0 0 3 3 3 1 Alternative splicing regulator Surp PF01805.20 RLN87423.1 - 0.0025 17.8 0.0 0.006 16.6 0.0 1.6 1 0 0 1 1 1 1 Surp module Abhydrolase_2 PF02230.16 RLN87424.1 - 0.071 12.9 0.1 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Helicase_C PF00271.31 RLN87426.1 - 3.7e-16 59.4 0.0 1e-15 58.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RLN87426.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase HET PF06985.11 RLN87426.1 - 0.12 12.7 0.9 0.38 11.1 0.0 2.2 2 0 0 2 2 2 0 Heterokaryon incompatibility protein (HET) Pex19 PF04614.12 RLN87427.1 - 0.018 14.9 1.8 0.05 13.4 1.3 1.8 1 1 1 2 2 2 0 Pex19 protein family BAR PF03114.18 RLN87427.1 - 0.029 14.0 1.9 0.035 13.7 0.2 2.0 2 1 0 2 2 2 0 BAR domain FCH PF00611.23 RLN87427.1 - 0.052 13.8 3.6 0.085 13.2 0.2 2.9 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain DUF2046 PF09755.9 RLN87427.1 - 0.06 12.6 2.3 0.14 11.4 0.6 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) BAG6 PF12057.8 RLN87427.1 - 0.064 12.9 0.5 0.11 12.1 0.1 1.7 2 0 0 2 2 2 0 BCL2-associated athanogene 6 PX PF00787.24 RLN87428.1 - 5.2e-10 39.3 0.3 1.2e-08 34.9 0.3 2.7 1 1 0 1 1 1 1 PX domain Clusterin PF01093.17 RLN87428.1 - 0.033 13.2 0.2 0.63 9.0 0.0 2.2 2 0 0 2 2 2 0 Clusterin FAD_binding_4 PF01565.23 RLN87429.1 - 2.9e-25 88.6 2.9 2.9e-25 88.6 2.9 1.9 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.12 RLN87429.1 - 2.2e-17 62.9 0.1 4.2e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like bZIP_2 PF07716.15 RLN87430.1 - 0.0029 17.6 5.2 0.0055 16.8 5.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 RLN87430.1 - 0.0092 16.1 6.0 0.0092 16.1 6.0 1.6 2 0 0 2 2 2 1 bZIP transcription factor DUF3450 PF11932.8 RLN87430.1 - 0.031 13.6 0.1 0.047 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4618 PF15397.6 RLN87430.1 - 0.047 13.1 0.3 0.72 9.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Protocadherin PF08374.11 RLN87430.1 - 0.11 12.5 0.1 0.52 10.2 0.1 1.8 2 0 0 2 2 2 0 Protocadherin bZIP_Maf PF03131.17 RLN87430.1 - 0.23 12.0 4.1 0.45 11.1 4.1 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_1 PF00170.21 RLN87432.1 - 0.0042 17.2 1.8 0.0072 16.4 1.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RLN87432.1 - 0.0077 16.3 2.6 0.014 15.5 2.6 1.3 1 0 0 1 1 1 1 Basic region leucine zipper PX PF00787.24 RLN87435.1 - 9.9e-06 25.5 0.3 2.3e-05 24.3 0.1 1.6 2 0 0 2 2 2 1 PX domain TRP PF06011.12 RLN87436.1 - 7.4e-23 81.0 7.8 1.4e-22 80.1 7.8 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel Serglycin PF04360.12 RLN87436.1 - 4 7.4 6.8 1.9 8.4 0.4 2.8 2 0 0 2 2 2 0 Serglycin Bromodomain PF00439.25 RLN87437.1 - 2.9e-18 65.7 0.0 1.7e-17 63.2 0.0 2.0 2 0 0 2 2 2 1 Bromodomain BET PF17035.5 RLN87437.1 - 1.3e-12 47.7 0.1 2.2e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation cNMP_binding PF00027.29 RLN87438.1 - 6.8e-15 54.9 0.1 3.4e-08 33.5 0.0 3.5 3 1 1 4 4 4 2 Cyclic nucleotide-binding domain Glyco_hydro81C PF17652.1 RLN87439.1 - 6.7e-108 361.0 0.2 1e-107 360.5 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 RLN87439.1 - 3.4e-26 92.2 2.1 5e-26 91.6 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain TetR_C_31 PF17940.1 RLN87439.1 - 0.093 12.9 0.1 0.42 10.8 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain RbpA PF13397.6 RLN87440.1 - 0.57 10.8 4.9 0.44 11.2 2.8 1.8 2 0 0 2 2 2 0 RNA polymerase-binding protein Anoctamin PF04547.12 RLN87443.1 - 9.9e-08 31.2 1.3 3.4e-05 22.9 0.3 2.1 2 0 0 2 2 2 2 Calcium-activated chloride channel PHM7_cyt PF14703.6 RLN87443.1 - 1.8e-07 31.5 0.0 2.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Gal_Lectin PF02140.18 RLN87443.1 - 0.075 13.5 0.0 0.075 13.5 0.0 2.7 3 0 0 3 3 3 0 Galactose binding lectin domain UNC-93 PF05978.16 RLN87443.1 - 0.13 12.0 2.5 8.1 6.1 0.2 2.3 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 Bac_export_1 PF01311.20 RLN87443.1 - 0.43 10.1 4.3 5.2 6.6 0.4 2.8 2 1 1 3 3 3 0 Bacterial export proteins, family 1 Methyltransf_16 PF10294.9 RLN87445.1 - 2.3e-24 86.0 0.0 4.5e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 RLN87445.1 - 0.079 12.3 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 RLN87445.1 - 0.11 12.1 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 RLN87445.1 - 0.12 13.1 0.2 0.28 11.9 0.2 1.6 1 0 0 1 1 1 0 Methyltransferase domain CDC45 PF02724.14 RLN87445.1 - 0.13 10.5 12.9 0.2 9.9 12.9 1.2 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 RLN87445.1 - 6.6 5.4 10.3 9.7 4.9 10.3 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Abhydrolase_3 PF07859.13 RLN87446.1 - 1.7e-21 77.0 0.0 2.7e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 RLN87446.1 - 2.7e-06 26.5 0.1 1.7e-05 23.9 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 RLN87446.1 - 3e-06 26.9 0.0 0.00014 21.4 0.0 2.9 2 1 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 RLN87446.1 - 0.0076 15.5 0.1 0.5 9.6 0.0 2.6 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN87446.1 - 0.18 12.4 3.9 0.64 10.6 3.9 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 RLN87447.1 - 2.4e-49 168.0 0.1 1e-23 84.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 RLN87447.1 - 1.7e-15 56.9 0.0 5.2e-07 28.9 0.0 2.9 2 1 0 2 2 2 2 Carboxylesterase family Peptidase_S9 PF00326.21 RLN87447.1 - 2.4e-13 50.1 1.8 3.3e-06 26.7 0.9 4.3 2 2 0 2 2 2 2 Prolyl oligopeptidase family DUF2974 PF11187.8 RLN87447.1 - 5.5e-05 22.8 0.0 0.035 13.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Say1_Mug180 PF10340.9 RLN87447.1 - 0.0038 16.1 0.0 1.1 8.0 0.0 2.4 2 0 0 2 2 2 2 Steryl acetyl hydrolase Complex1_LYR PF05347.15 RLN87447.1 - 0.028 14.4 1.0 5.5 7.1 0.1 2.5 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Esterase_phd PF10503.9 RLN87447.1 - 0.049 13.1 0.2 6.6 6.2 0.0 2.4 2 0 0 2 2 2 0 Esterase PHB depolymerase Hydrolase_4 PF12146.8 RLN87447.1 - 0.059 12.6 0.1 7.8 5.7 0.0 3.5 4 0 0 4 4 4 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 RLN87447.1 - 0.076 12.9 0.0 8.6 6.2 0.0 2.8 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_6 PF12697.7 RLN87447.1 - 1.3 9.6 15.6 0.92 10.1 2.8 3.2 3 2 0 3 3 3 0 Alpha/beta hydrolase family DnaJ PF00226.31 RLN87448.1 - 4.3e-40 135.7 0.9 3.1e-19 68.8 0.1 3.2 2 0 0 2 2 2 2 DnaJ domain Lipase_3 PF01764.25 RLN87448.1 - 6.2e-14 52.1 0.2 0.069 13.0 0.0 5.4 5 0 0 5 5 5 4 Lipase (class 3) DUF2974 PF11187.8 RLN87448.1 - 1.4e-05 24.8 0.0 0.28 10.7 0.0 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 RLN87448.1 - 3.1e-05 23.4 0.1 0.26 10.5 0.0 3.0 3 0 0 3 3 3 2 Serine aminopeptidase, S33 EF-hand_1 PF00036.32 RLN87448.1 - 0.00012 21.3 0.0 0.095 12.3 0.0 2.9 2 0 0 2 2 2 2 EF hand PGAP1 PF07819.13 RLN87448.1 - 0.00033 20.5 0.0 0.33 10.6 0.0 2.5 2 0 0 2 2 2 2 PGAP1-like protein EF-hand_6 PF13405.6 RLN87448.1 - 0.0012 18.6 0.0 3.4 7.9 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain SNARE_assoc PF09335.11 RLN87448.1 - 0.012 16.1 7.1 0.34 11.4 1.3 2.8 2 0 0 2 2 2 0 SNARE associated Golgi protein Phage_holin_3_6 PF07332.11 RLN87448.1 - 0.015 15.3 20.4 0.024 14.7 2.1 3.9 4 0 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III EF-hand_7 PF13499.6 RLN87448.1 - 0.021 15.3 0.6 6.6 7.3 0.0 4.1 4 0 0 4 4 4 0 EF-hand domain pair EF-hand_8 PF13833.6 RLN87448.1 - 0.028 14.3 0.0 0.15 11.9 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair YgbB PF02542.16 RLN87448.1 - 0.075 13.3 0.0 20 5.4 0.0 3.1 2 0 0 2 2 2 0 YgbB family EMP70 PF02990.16 RLN87449.1 - 7e-151 503.4 4.1 9.1e-151 503.0 4.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Arrestin_C PF02752.22 RLN87449.1 - 0.032 14.7 0.0 0.054 13.9 0.0 1.3 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain CorA PF01544.18 RLN87449.1 - 0.4 9.9 4.5 0.11 11.8 0.5 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein PsbN PF02468.15 RLN87449.1 - 7.5 6.5 6.3 1.4 8.8 0.4 3.0 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) Methyltransf_16 PF10294.9 RLN87450.1 - 3e-29 102.0 0.0 5.6e-29 101.1 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 RLN87450.1 - 1.6e-05 24.8 0.0 2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN87450.1 - 0.0023 17.5 0.0 0.0039 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 RLN87450.1 - 0.069 13.9 0.0 0.26 12.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain YwiC PF14256.6 RLN87451.1 - 0.0032 17.8 3.8 0.0032 17.8 3.8 2.3 1 1 1 2 2 2 1 YwiC-like protein C2 PF00168.30 RLN87451.1 - 0.016 15.5 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 C2 domain DUF2207 PF09972.9 RLN87451.1 - 0.097 11.4 0.2 0.11 11.2 0.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phage_holin_3_6 PF07332.11 RLN87451.1 - 1.1 9.3 11.7 2.4 8.2 11.7 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DEAD PF00270.29 RLN87452.1 - 3.8e-06 26.8 0.4 0.014 15.2 0.1 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN87452.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.8 1 1 0 1 1 1 0 Helicase conserved C-terminal domain CBS PF00571.28 RLN87452.1 - 0.057 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 CBS domain DUF5093 PF17011.5 RLN87453.1 - 0.15 12.3 3.1 0.46 10.8 3.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) Iron_permease PF04120.12 RLN87453.1 - 0.39 10.5 3.3 1.3 8.8 3.3 1.9 1 0 0 1 1 1 0 Low affinity iron permease CLZ PF16526.5 RLN87453.1 - 0.58 10.6 19.4 0.38 11.1 0.9 4.9 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_1 PF00170.21 RLN87454.1 - 0.16 12.1 3.2 0.36 11.0 3.2 1.6 1 0 0 1 1 1 0 bZIP transcription factor TSC22 PF01166.18 RLN87455.1 - 0.14 12.4 0.4 0.14 12.4 0.4 2.7 2 2 1 3 3 3 0 TSC-22/dip/bun family MnmE_helical PF12631.7 RLN87456.1 - 0.043 14.0 0.5 0.23 11.6 0.5 2.0 1 1 0 1 1 1 0 MnmE helical domain Pkip-1 PF06878.11 RLN87456.1 - 0.12 12.5 5.2 4.6 7.3 0.6 2.8 3 0 0 3 3 3 0 Pkip-1 protein DHR10 PF18595.1 RLN87456.1 - 0.29 11.2 16.9 0.07 13.2 7.9 2.6 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain ABC_tran_CTD PF16326.5 RLN87456.1 - 5.5 7.3 17.2 5 7.4 1.7 3.3 2 1 0 2 2 2 0 ABC transporter C-terminal domain FUSC PF04632.12 RLN87456.1 - 8.7 4.7 8.9 13 4.1 8.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family KRAP_IP3R_bind PF14722.6 RLN87457.1 - 0.11 12.2 0.4 0.23 11.2 0.4 1.6 1 0 0 1 1 1 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain Ank_2 PF12796.7 RLN87459.1 - 1.3e-31 109.0 20.7 1.4e-12 48.0 2.5 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN87459.1 - 2.1e-21 75.7 12.1 2.7e-08 33.9 0.2 5.4 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN87459.1 - 3.3e-19 66.9 14.0 0.00011 22.4 0.3 6.9 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 RLN87459.1 - 4.5e-18 64.8 19.2 0.0009 19.6 2.2 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 RLN87459.1 - 3.1e-17 62.7 11.8 1.3e-08 35.2 1.8 4.4 4 0 0 4 4 4 3 Ankyrin repeats (many copies) PA PF02225.22 RLN87459.1 - 6.6e-17 61.3 0.3 2.3e-07 30.8 0.0 3.0 3 0 0 3 3 3 2 PA domain TPR_2 PF07719.17 RLN87459.1 - 0.02 15.0 0.2 0.078 13.1 0.2 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat GAS PF13851.6 RLN87459.1 - 0.032 13.6 4.1 0.07 12.5 4.1 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 RLN87459.1 - 1.1 9.5 7.0 3.1 8.1 7.0 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding IQ PF00612.27 RLN87459.1 - 6.8 6.8 6.5 5.5 7.1 1.4 2.9 2 0 0 2 2 2 0 IQ calmodulin-binding motif PNP_UDP_1 PF01048.20 RLN87460.1 - 6.8e-18 64.8 0.1 7.5e-17 61.4 0.1 2.3 1 1 0 1 1 1 1 Phosphorylase superfamily DUF1883 PF08980.10 RLN87460.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1883) Peptidase_C12 PF01088.21 RLN87461.1 - 3.4e-32 111.9 2.1 1.8e-29 103.0 2.1 3.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Cation_efflux PF01545.21 RLN87462.1 - 4.3e-42 144.1 4.0 1.3e-41 142.6 4.0 1.7 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 RLN87462.1 - 1.9e-10 40.7 1.4 4.6e-10 39.5 1.4 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Pkinase_Tyr PF07714.17 RLN87463.1 - 1.3e-36 126.2 0.0 2.5e-34 118.7 0.0 3.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN87463.1 - 1.8e-30 106.2 0.0 4.6e-30 104.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Actin PF00022.19 RLN87463.1 - 4.6e-14 51.9 0.0 8e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 Actin APH PF01636.23 RLN87463.1 - 0.041 13.8 0.4 0.15 12.0 0.4 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family tRNA-synt_1c PF00749.21 RLN87464.1 - 2.1e-99 332.4 0.1 2.1e-99 332.4 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 RLN87464.1 - 3.1e-35 121.6 0.0 8.5e-35 120.2 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain WHEP-TRS PF00458.20 RLN87464.1 - 1.5e-14 53.9 0.8 1.5e-14 53.9 0.8 2.7 2 0 0 2 2 2 1 WHEP-TRS domain GST_C PF00043.25 RLN87464.1 - 5.7e-06 26.5 0.0 5.7e-06 26.5 0.0 2.7 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RLN87464.1 - 6.2e-05 23.1 0.0 0.00037 20.6 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RLN87464.1 - 0.003 17.5 0.8 0.0082 16.2 0.8 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 RLN87464.1 - 0.051 12.9 0.1 0.091 12.1 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain MSA_2 PF00985.17 RLN87464.1 - 3.6 7.9 8.5 6.8 7.0 8.5 1.4 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Chromo PF00385.24 RLN87465.1 - 1.4e-07 31.3 0.3 1.4e-07 31.3 0.3 3.2 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain ECH_2 PF16113.5 RLN87465.1 - 0.19 11.2 1.5 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase CSN8_PSD8_EIF3K PF10075.9 RLN87466.1 - 1e-17 64.4 0.0 3.4e-17 62.8 0.0 1.8 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 RLN87466.1 - 0.0004 19.9 0.0 0.00059 19.3 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family DUF3243 PF11588.8 RLN87467.1 - 0.095 13.0 0.2 0.47 10.8 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3243) RecO_N PF11967.8 RLN87467.1 - 0.14 12.2 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Recombination protein O N terminal ABC2_membrane PF01061.24 RLN87469.1 - 2.8e-68 229.5 77.0 1.7e-37 128.9 27.2 2.6 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN87469.1 - 2.6e-34 118.7 0.1 5.2e-16 59.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 RLN87469.1 - 7e-09 36.3 0.2 0.0024 18.3 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain ABC2_membrane_3 PF12698.7 RLN87469.1 - 1.7e-08 34.0 56.4 3.7e-06 26.3 17.8 3.3 2 2 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 RLN87469.1 - 1.1e-07 31.9 1.7 0.0088 16.0 0.3 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 RLN87469.1 - 1.1e-07 32.0 0.1 0.071 12.9 0.0 3.4 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN87469.1 - 6.9e-06 25.7 5.6 0.016 14.9 0.8 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN87469.1 - 1.5e-05 24.7 0.2 0.051 13.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RLN87469.1 - 3.7e-05 24.0 0.0 0.082 13.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN87469.1 - 8.6e-05 21.9 0.7 0.011 15.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin PDR_CDR PF06422.12 RLN87469.1 - 0.00015 21.6 0.0 0.00015 21.6 0.0 4.6 5 1 1 6 6 5 1 CDR ABC transporter AAA_23 PF13476.6 RLN87469.1 - 0.00082 19.9 1.3 0.28 11.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RLN87469.1 - 0.0017 18.8 0.3 5.6 7.4 0.2 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 RLN87469.1 - 0.0031 17.0 0.6 7.5 5.9 0.1 3.9 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 RLN87469.1 - 0.0032 17.2 0.2 0.95 9.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RLN87469.1 - 0.0086 16.6 0.0 5.8 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 RLN87469.1 - 0.013 15.5 0.2 0.7 9.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 RLN87469.1 - 0.015 15.4 3.8 1 9.5 0.1 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase ABC_ATPase PF09818.9 RLN87469.1 - 0.018 13.9 0.6 3.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class cobW PF02492.19 RLN87469.1 - 0.019 14.6 3.1 1.1 8.8 0.4 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 RLN87469.1 - 0.023 13.9 0.1 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit DUF815 PF05673.13 RLN87469.1 - 0.029 13.5 0.2 0.078 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 RLN87469.1 - 0.036 14.2 0.1 6.3 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RLN87469.1 - 0.045 13.5 1.8 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 RLN87469.1 - 0.05 13.8 0.6 3.8 7.8 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 RLN87469.1 - 0.062 13.0 1.5 4.1 7.2 0.3 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 RLN87469.1 - 0.077 13.3 0.4 15 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 RLN87469.1 - 0.11 12.4 1.2 3.8 7.5 0.2 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 RLN87469.1 - 0.14 12.0 5.4 4.3 7.2 0.2 2.7 2 0 0 2 2 2 0 NACHT domain Ploopntkinase3 PF18751.1 RLN87469.1 - 0.17 11.8 0.2 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 PDR_assoc PF08370.11 RLN87469.1 - 0.2 11.5 19.2 0.028 14.2 1.1 4.1 4 0 0 4 4 3 0 Plant PDR ABC transporter associated AAA_7 PF12775.7 RLN87469.1 - 0.29 10.6 1.4 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 RLN87469.1 - 3.3 7.8 4.0 5.9 6.9 0.1 2.6 3 0 0 3 3 2 0 Dynamin family PDR_CDR PF06422.12 RLN87470.1 - 1.3e-09 37.8 0.0 1.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 CDR ABC transporter PDR_assoc PF08370.11 RLN87470.1 - 0.0011 18.6 0.3 0.0011 18.6 0.3 1.8 2 1 0 2 2 2 1 Plant PDR ABC transporter associated ABC2_membrane PF01061.24 RLN87471.1 - 1.8e-32 112.5 29.6 2.6e-32 111.9 29.6 1.3 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN87471.1 - 8.5e-07 28.8 0.7 8.7e-06 25.6 0.0 2.6 2 0 0 2 2 2 1 CDR ABC transporter PDR_assoc PF08370.11 RLN87471.1 - 0.9 9.3 8.8 4.2 7.2 0.0 3.9 3 0 0 3 3 3 0 Plant PDR ABC transporter associated ABC2_membrane_3 PF12698.7 RLN87471.1 - 1.9 7.5 28.2 6.1 5.8 28.2 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane PF01061.24 RLN87472.1 - 1.3e-67 227.3 72.5 2.5e-37 128.4 27.1 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN87472.1 - 2.2e-34 118.9 0.1 9.8e-16 58.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN87472.1 - 4.3e-07 30.0 0.4 0.071 12.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN87472.1 - 3.2e-06 27.6 0.0 0.0034 17.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 RLN87472.1 - 4.6e-06 26.6 1.0 0.066 13.1 0.2 2.3 2 0 0 2 2 2 2 RsgA GTPase ABC2_membrane_3 PF12698.7 RLN87472.1 - 4.7e-06 26.0 64.0 0.0022 17.2 18.9 3.2 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.6 RLN87472.1 - 5.7e-06 26.0 4.0 0.039 13.7 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain PDR_CDR PF06422.12 RLN87472.1 - 6.1e-06 26.1 4.8 0.00077 19.3 0.0 3.4 3 0 0 3 3 2 1 CDR ABC transporter AAA_25 PF13481.6 RLN87472.1 - 6.2e-06 25.9 0.3 0.13 11.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RLN87472.1 - 3e-05 24.3 0.0 0.14 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RLN87472.1 - 0.00033 21.2 0.4 0.08 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RLN87472.1 - 0.00033 20.0 1.7 0.027 13.8 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.29 RLN87472.1 - 0.0026 18.2 0.3 6.1 7.3 0.2 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 RLN87472.1 - 0.0047 16.7 0.2 2.2 8.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 RLN87472.1 - 0.0059 16.2 2.6 0.52 9.9 0.5 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 RLN87472.1 - 0.014 14.6 0.3 0.031 13.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SMC_N PF02463.19 RLN87472.1 - 0.014 14.8 0.8 8.6 5.7 0.1 3.6 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RLN87472.1 - 0.023 14.7 1.1 6.3 6.9 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase TsaE PF02367.17 RLN87472.1 - 0.036 14.1 1.1 1.9 8.5 0.2 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 RLN87472.1 - 0.043 14.4 0.0 15 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 RLN87472.1 - 0.045 12.5 1.0 4.5 6.0 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_5 PF07728.14 RLN87472.1 - 0.05 13.6 0.1 1.5 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 RLN87472.1 - 0.057 12.6 0.3 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 RLN87472.1 - 0.074 12.6 1.4 0.79 9.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region PDR_assoc PF08370.11 RLN87472.1 - 0.1 12.3 18.1 0.044 13.5 0.9 4.6 4 0 0 4 4 4 0 Plant PDR ABC transporter associated AAA_19 PF13245.6 RLN87472.1 - 0.13 12.6 0.3 25 5.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RLN87472.1 - 0.14 11.9 0.2 10 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RLN87472.1 - 0.15 12.0 5.5 2 8.3 0.2 2.7 2 0 0 2 2 2 0 NACHT domain Ploopntkinase3 PF18751.1 RLN87472.1 - 0.17 11.7 0.2 1.9 8.4 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 RLN87472.1 - 0.19 11.9 0.1 25 5.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 RLN87472.1 - 0.2 11.4 0.1 0.55 9.9 0.0 1.7 2 0 0 2 2 2 0 Virulence-associated protein E PduV-EutP PF10662.9 RLN87472.1 - 0.28 10.9 2.0 4 7.2 0.4 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 RLN87472.1 - 1.9 8.5 5.2 5.8 6.9 2.3 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Kisspeptin PF15152.6 RLN87473.1 - 4 8.3 6.2 0.74 10.6 1.2 2.4 2 1 0 2 2 2 0 Kisspeptin GalBD_like PF17974.1 RLN87474.1 - 0.1 12.7 0.2 0.18 11.9 0.2 1.3 1 0 0 1 1 1 0 Galactose-binding domain-like DUF4307 PF14155.6 RLN87474.1 - 0.12 12.2 0.2 0.55 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) APC_u9 PF16633.5 RLN87474.1 - 0.16 13.1 2.2 0.24 12.5 0.0 2.0 2 0 0 2 2 2 0 Unstructured region on APC between 1st two creatine-rich regions RNase_J_C PF17770.1 RLN87476.1 - 0.057 14.5 3.2 0.11 13.6 2.0 2.1 1 1 1 2 2 2 0 Ribonuclease J C-terminal domain tRNA-synt_1e PF01406.19 RLN87477.1 - 5.2e-107 357.7 0.0 9e-107 356.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 RLN87477.1 - 5.3e-12 45.2 2.7 1.2e-06 27.6 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 RLN87477.1 - 7e-05 21.3 0.0 0.0066 14.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 RLN87477.1 - 0.00049 20.5 0.2 0.0019 18.6 0.2 2.1 1 0 0 1 1 1 1 DALR domain tRNA-synt_1c PF00749.21 RLN87477.1 - 0.032 13.1 0.0 0.093 11.6 0.0 1.8 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Tetraspanin PF00335.20 RLN87478.1 - 0.058 13.1 0.3 0.091 12.5 0.3 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF2975 PF11188.8 RLN87478.1 - 0.064 13.1 5.2 0.098 12.5 4.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) SPC22 PF04573.12 RLN87479.1 - 1.8e-49 167.5 0.8 1.5e-37 128.7 0.0 2.0 2 0 0 2 2 2 2 Signal peptidase subunit Surp PF01805.20 RLN87480.1 - 1.3e-14 53.9 1.9 1.6e-14 53.6 0.2 2.1 2 0 0 2 2 2 1 Surp module CTD_bind PF04818.13 RLN87480.1 - 1.3e-06 29.2 0.0 3.8e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CTK3 PF12243.8 RLN87480.1 - 0.0049 16.9 0.1 0.009 16.0 0.1 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 RRM_1 PF00076.22 RLN87480.1 - 0.1 12.4 0.0 0.31 10.9 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Caskin-Pro-rich PF16907.5 RLN87480.1 - 1.8 9.1 8.1 14 6.3 0.9 3.8 2 1 1 3 3 3 0 Proline rich region of Caskin proteins Proteasome PF00227.26 RLN87482.1 - 2.1e-34 118.7 0.0 2.6e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit GalKase_gal_bdg PF10509.9 RLN87483.1 - 2.3e-19 68.7 0.0 4.7e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 RLN87483.1 - 1.6e-12 47.5 0.1 3.4e-12 46.4 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GalKase_gal_bdg PF10509.9 RLN87484.1 - 1.9e-19 69.0 0.0 3.8e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 RLN87484.1 - 1.2e-12 47.9 0.1 2.6e-12 46.8 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain ABC_trans_N PF14510.6 RLN87485.1 - 0.074 13.7 0.0 0.17 12.5 0.0 1.7 1 1 0 1 1 1 0 ABC-transporter N-terminal Thioredoxin_15 PF18403.1 RLN87485.1 - 0.098 12.6 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain ABC2_membrane PF01061.24 RLN87486.1 - 5.9e-33 114.1 30.7 5.9e-33 114.1 30.7 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RLN87486.1 - 5e-19 69.2 1.2 6e-16 59.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 RLN87486.1 - 0.00021 21.3 0.3 0.091 12.7 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 RLN87486.1 - 0.00025 20.7 3.0 0.01 15.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN87486.1 - 0.00029 21.2 1.3 0.0016 18.8 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RLN87486.1 - 0.0082 16.4 0.5 0.3 11.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 RLN87486.1 - 0.043 13.0 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 RLN87486.1 - 0.047 13.4 0.1 0.46 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 RLN87486.1 - 0.048 13.2 0.7 6.1 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 RLN87486.1 - 0.12 11.6 0.0 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.23 RLN87486.1 - 0.15 12.2 0.1 0.37 10.9 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase PDR_CDR PF06422.12 RLN87486.1 - 0.15 12.0 2.4 1.7 8.6 0.7 2.7 2 0 0 2 2 2 0 CDR ABC transporter SMC_N PF02463.19 RLN87486.1 - 0.15 11.5 1.3 1 8.7 0.1 2.5 2 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 RLN87486.1 - 0.25 11.4 0.4 0.78 9.8 0.2 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain ABC2_membrane_3 PF12698.7 RLN87486.1 - 5.8 5.9 34.7 0.013 14.6 23.2 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein PDR_assoc PF08370.11 RLN87486.1 - 7.9 6.3 9.0 0.072 12.8 0.6 1.9 2 0 0 2 2 1 0 Plant PDR ABC transporter associated SEF14_adhesin PF06443.11 RLN87487.1 - 0.033 14.1 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 SEF14-like adhesin zf-BED PF02892.15 RLN87487.1 - 0.16 12.0 0.1 0.4 10.8 0.1 1.6 1 0 0 1 1 1 0 BED zinc finger Ntox22 PF15527.6 RLN87487.1 - 0.17 11.9 0.2 0.31 11.1 0.2 1.4 1 0 0 1 1 1 0 Bacterial toxin 22 SAM_2 PF07647.17 RLN87488.1 - 6.8e-11 42.1 0.0 1.2e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RLN87488.1 - 8.5e-10 38.9 0.0 1.5e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Glyco_transf_22 PF03901.17 RLN87489.1 - 3.9e-40 138.3 17.4 4e-38 131.7 17.4 2.0 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family Cupin_4 PF08007.12 RLN87490.1 - 1.6e-06 27.8 0.1 0.00049 19.7 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein Cupin_2 PF07883.11 RLN87490.1 - 0.044 13.5 0.0 2.2 8.0 0.0 2.6 2 0 0 2 2 2 0 Cupin domain Choline_transpo PF04515.12 RLN87491.1 - 9e-67 225.6 10.3 1e-66 225.4 10.3 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter Sdh_cyt PF01127.22 RLN87491.1 - 0.41 10.7 4.5 0.086 12.9 0.8 1.7 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit ANAPC4_WD40 PF12894.7 RLN87492.1 - 1.6e-07 31.6 0.0 0.0064 16.8 0.0 3.5 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RLN87492.1 - 3.8e-06 27.5 5.0 0.08 13.8 0.3 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.11 RLN87492.1 - 0.13 12.1 0.0 17 5.2 0.0 3.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF4611 PF15387.6 RLN87492.1 - 0.23 11.7 3.5 0.59 10.4 3.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Glyco_hydro_31 PF01055.26 RLN87493.1 - 1.2e-120 403.7 0.0 1.5e-120 403.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 RLN87493.1 - 2.3e-27 95.5 0.0 4.7e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 RLN87493.1 - 1.5e-08 34.3 14.9 1.4e-05 24.9 4.6 2.6 2 0 0 2 2 2 2 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.6 RLN87493.1 - 3.8e-07 30.3 0.0 1.2e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like DUF4006 PF13179.6 RLN87493.1 - 0.043 13.7 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Ank_5 PF13857.6 RLN87494.1 - 0.046 14.1 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) KIAA1430 PF13879.6 RLN87495.1 - 1.2e-14 54.9 5.5 2.4e-14 53.9 5.5 1.5 1 0 0 1 1 1 1 KIAA1430 homologue MatE PF01554.18 RLN87496.1 - 4.4e-22 78.4 12.3 4.4e-22 78.4 12.3 2.3 2 1 0 2 2 2 1 MatE CBS PF00571.28 RLN87497.1 - 0.06 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 CBS domain Proteasome PF00227.26 RLN87498.1 - 6.1e-31 107.4 0.0 7e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit zf-CCHC_3 PF13917.6 RLN87499.1 - 2.7e-19 68.8 3.1 6e-19 67.7 3.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 RLN87499.1 - 0.41 10.8 1.9 0.85 9.8 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Macoilin PF09726.9 RLN87499.1 - 0.65 8.5 24.6 0.68 8.4 24.6 1.1 1 0 0 1 1 1 0 Macoilin family GMC_oxred_N PF00732.19 RLN87500.1 - 5.2e-100 334.6 0.0 7.3e-100 334.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 RLN87500.1 - 2.9e-37 128.4 0.0 5.1e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 RLN87500.1 - 1.2e-06 27.9 1.2 0.029 13.5 0.0 2.8 3 0 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.12 RLN87500.1 - 2.3e-05 23.6 0.1 3.5e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 RLN87500.1 - 5e-05 23.1 1.1 0.00071 19.3 1.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RLN87500.1 - 0.00048 20.3 0.0 0.0019 18.4 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 RLN87500.1 - 0.0015 17.9 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 RLN87500.1 - 0.0015 17.8 0.3 0.0081 15.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RLN87500.1 - 0.009 15.4 0.4 0.52 9.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 RLN87500.1 - 0.025 13.8 0.2 0.061 12.5 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 RLN87500.1 - 0.032 14.8 0.1 1.1 9.8 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RLN87500.1 - 0.057 12.1 0.1 0.17 10.6 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 RLN87500.1 - 0.15 12.3 0.0 0.55 10.5 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Calreticulin PF00262.18 RLN87501.1 - 3.2e-146 486.9 4.9 4.1e-146 486.6 4.9 1.1 1 0 0 1 1 1 1 Calreticulin family DUF883 PF05957.13 RLN87501.1 - 0.2 12.3 0.1 0.2 12.3 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) FAM176 PF14851.6 RLN87501.1 - 2.8 7.6 5.9 1 9.0 0.1 2.9 2 1 1 3 3 3 0 FAM176 family HAUS-augmin3 PF14932.6 RLN87502.1 - 0.046 13.3 14.1 0.55 9.8 8.7 2.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 GMC_oxred_N PF00732.19 RLN87503.1 - 6.6e-48 163.6 0.3 5e-34 118.0 0.3 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 RLN87503.1 - 9.4e-24 84.6 0.1 1.2e-23 84.2 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 RLN87503.1 - 1e-08 34.7 0.4 0.0011 18.1 0.1 2.2 1 1 1 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 RLN87503.1 - 1.2e-05 24.6 0.0 1.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 RLN87503.1 - 2.7e-05 23.9 0.6 0.00071 19.2 0.0 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RLN87503.1 - 2.7e-05 23.5 0.0 4.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 RLN87503.1 - 5.1e-05 23.5 0.0 0.047 14.0 0.0 2.3 2 0 0 2 2 2 2 TrkA-N domain Pyr_redox PF00070.27 RLN87503.1 - 0.00083 19.9 0.1 1.4 9.6 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RLN87503.1 - 0.0011 19.2 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 RLN87503.1 - 0.0016 17.7 0.3 0.0047 16.2 0.0 1.8 2 0 0 2 2 2 1 Thi4 family ApbA PF02558.16 RLN87503.1 - 0.016 14.8 0.0 0.049 13.3 0.0 1.8 2 1 1 3 3 3 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 RLN87503.1 - 0.021 14.2 0.1 0.22 10.8 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 RLN87503.1 - 0.035 12.8 0.1 0.14 10.9 0.0 1.8 1 1 1 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 RLN87503.1 - 0.093 12.0 0.0 3.3 6.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2647 PF10839.8 RLN87503.1 - 0.16 12.1 0.1 0.88 9.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2647) Pkinase PF00069.25 RLN87504.1 - 7.2e-37 127.2 0.0 1.8e-30 106.2 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN87504.1 - 1.3e-24 86.8 0.0 7.1e-16 58.3 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 RLN87504.1 - 0.012 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 RLN87504.1 - 0.076 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN87504.1 - 0.1 11.3 0.2 0.17 10.6 0.2 1.3 1 1 0 1 1 1 0 Fungal protein kinase Porphobil_deam PF01379.20 RLN87505.1 - 6e-65 218.6 0.0 8.7e-65 218.0 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Sugar_tr PF00083.24 RLN87505.1 - 7.5e-15 54.7 15.7 7.5e-15 54.7 15.7 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN87505.1 - 2.1e-07 30.2 4.4 2.8e-07 29.8 4.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily FIST_C PF10442.9 RLN87505.1 - 0.097 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 FIST C domain Porphobil_deam PF01379.20 RLN87506.1 - 4.5e-65 219.0 0.0 5.8e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain FIST_C PF10442.9 RLN87506.1 - 0.012 15.6 0.0 0.055 13.4 0.0 2.0 2 0 0 2 2 2 0 FIST C domain Ion_trans PF00520.31 RLN87507.1 - 1.7e-25 89.7 11.1 5e-15 55.4 3.8 2.1 2 0 0 2 2 2 2 Ion transport protein cNMP_binding PF00027.29 RLN87507.1 - 5.6e-13 48.8 0.0 9.7e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 RLN87507.1 - 0.00021 21.2 0.2 0.00021 21.2 0.2 3.1 3 0 0 3 3 3 2 Ion channel cNMP_binding PF00027.29 RLN87508.1 - 1.1e-48 163.2 4.1 2.2e-12 46.9 0.0 5.8 6 0 0 6 6 6 5 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN87508.1 - 1.1e-37 129.6 41.9 1.9e-15 56.8 2.7 4.3 4 0 0 4 4 4 4 Ion transport protein Se-cys_synth_N PF12390.8 RLN87508.1 - 0.085 13.1 0.1 39 4.6 0.0 3.3 3 0 0 3 3 3 0 Selenocysteine synthase N terminal Ion_trans_2 PF07885.16 RLN87508.1 - 0.094 12.7 11.3 2.3 8.2 0.0 5.5 5 0 0 5 5 5 0 Ion channel WD40 PF00400.32 RLN87509.1 - 2.2e-36 123.2 15.2 2.2e-08 34.6 1.6 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.11 RLN87509.1 - 0.044 12.5 0.0 0.31 9.7 0.0 2.2 1 1 2 3 3 3 0 Nup133 N terminal like Myosin_head PF00063.21 RLN87510.1 - 5.7e-199 662.7 0.0 8e-199 662.2 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) SAP PF02037.27 RLN87510.1 - 1.8e-11 43.5 0.9 1.8e-11 43.5 0.9 2.4 2 0 0 2 2 2 1 SAP domain IQ PF00612.27 RLN87510.1 - 0.0014 18.3 13.7 0.035 13.9 0.2 3.5 3 0 0 3 3 3 2 IQ calmodulin-binding motif AAA_16 PF13191.6 RLN87510.1 - 0.057 13.8 0.0 0.057 13.8 0.0 3.4 2 1 0 2 2 2 0 AAA ATPase domain Tho1_MOS11_C PF18592.1 RLN87510.1 - 0.093 12.5 20.0 0.41 10.5 2.0 4.2 3 1 1 4 4 4 0 Tho1/MOS11 C-terminal domain AAA_22 PF13401.6 RLN87510.1 - 0.25 11.6 1.2 0.87 9.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 RLN87510.1 - 0.58 10.7 2.5 1.4 9.4 0.0 2.7 2 1 0 2 2 2 0 ABC transporter Mannosyl_trans3 PF11051.8 RLN87512.1 - 1.6e-35 122.8 0.0 1.4e-34 119.7 0.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative RNA_pol_Rpb2_6 PF00562.28 RLN87513.1 - 3.1e-125 418.3 0.0 4.4e-125 417.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_2 PF04561.14 RLN87513.1 - 2e-48 164.5 0.2 3.2e-48 163.9 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 RLN87513.1 - 1.5e-33 115.0 0.2 4.5e-33 113.5 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 RLN87513.1 - 2.6e-26 91.6 0.0 5.8e-26 90.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 RLN87513.1 - 4.6e-25 87.7 1.7 8.4e-25 86.8 0.7 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 RLN87513.1 - 5.2e-14 52.5 2.8 1.3e-13 51.3 2.8 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_1 PF04563.15 RLN87513.1 - 9.7e-09 35.0 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit Ion_trans PF00520.31 RLN87514.1 - 7.6e-14 51.5 15.5 7.2e-07 28.7 1.0 3.1 2 1 0 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 RLN87514.1 - 7.9e-14 51.4 15.4 1.3e-08 34.7 3.6 3.8 3 0 0 3 3 3 3 Ion channel cNMP_binding PF00027.29 RLN87514.1 - 2e-08 34.2 0.0 5.4e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DDE_Tnp_1_7 PF13843.6 RLN87515.1 - 4.9e-18 65.6 0.0 2.3e-10 40.3 0.1 2.1 1 1 1 2 2 2 2 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 RLN87515.1 - 0.009 16.8 2.0 0.029 15.2 2.0 1.8 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon XRN_M PF17846.1 RLN87516.1 - 9.4e-150 499.4 0.2 1.7e-149 498.5 0.0 1.5 2 0 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 RLN87516.1 - 5.1e-71 238.9 7.0 1.7e-61 207.8 0.0 3.2 2 1 1 3 3 3 2 XRN 5'-3' exonuclease N-terminus AMP-binding_C PF13193.6 RLN87517.1 - 0.0067 17.4 0.0 0.016 16.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF412 PF04217.13 RLN87517.1 - 0.11 12.3 0.8 0.24 11.3 0.8 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF412 MIR PF02815.19 RLN87518.1 - 8.5e-10 38.8 0.1 1e-08 35.3 0.1 2.1 1 1 1 2 2 2 2 MIR domain adh_short PF00106.25 RLN87519.1 - 3.1e-33 114.9 0.1 4.1e-33 114.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN87519.1 - 6.9e-24 84.7 0.3 9.2e-24 84.3 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 RLN87519.1 - 0.00076 19.0 0.1 0.0014 18.2 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 RLN87519.1 - 0.0012 18.8 0.2 0.0015 18.5 0.2 1.2 1 0 0 1 1 1 1 KR domain DBP10CT PF08147.12 RLN87520.1 - 4.8e-13 49.2 3.9 4.8e-13 49.2 3.9 2.0 2 0 0 2 2 2 1 DBP10CT (NUC160) domain Nefa_Nip30_N PF10187.9 RLN87521.1 - 4.5e-15 55.9 5.0 4.5e-15 55.9 5.0 2.3 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 RLN87521.1 - 0.0025 17.5 9.3 0.0032 17.1 9.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Coilin_N PF15862.5 RLN87521.1 - 0.02 14.7 1.2 0.047 13.5 1.2 1.7 1 1 0 1 1 1 0 Coilin N-terminus RR_TM4-6 PF06459.12 RLN87521.1 - 2.1 8.1 11.1 2.7 7.7 11.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TMA7 PF09072.10 RLN87522.1 - 1.5 9.7 10.2 0.2 12.5 2.9 2.5 2 0 0 2 2 2 0 Translation machinery associated TMA7 MutS_V PF00488.21 RLN87523.1 - 1e-78 263.7 0.1 1.8e-78 262.9 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 RLN87523.1 - 5.5e-25 88.7 0.2 1.2e-24 87.6 0.2 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 RLN87523.1 - 9.5e-09 35.5 0.1 2e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_28 PF13521.6 RLN87523.1 - 0.011 15.9 0.4 0.043 14.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 RLN87523.1 - 0.018 14.6 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MutS_II PF05188.17 RLN87523.1 - 0.021 15.1 0.3 0.1 12.9 0.0 2.2 3 0 0 3 3 3 0 MutS domain II NTPase_1 PF03266.15 RLN87523.1 - 0.07 13.0 0.8 9.5 6.1 0.1 3.4 3 0 0 3 3 3 0 NTPase Ank_2 PF12796.7 RLN87526.1 - 4.9e-128 418.0 18.9 1.6e-20 73.5 0.1 7.5 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN87526.1 - 2e-76 242.8 7.3 5.4e-05 23.3 0.0 13.4 13 0 0 13 13 13 12 Ankyrin repeat Ank PF00023.30 RLN87526.1 - 3.9e-73 238.9 9.3 1.2e-05 25.5 0.0 13.5 14 0 0 14 14 13 12 Ankyrin repeat Ank_5 PF13857.6 RLN87526.1 - 5.5e-72 236.9 26.6 3.1e-08 33.7 0.0 13.2 2 1 11 13 13 13 12 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN87526.1 - 4.5e-51 170.6 8.6 1.5e-07 31.8 0.0 9.4 5 3 5 10 10 10 9 Ankyrin repeats (many copies) Pkinase PF00069.25 RLN87526.1 - 6.8e-41 140.4 0.0 1.1e-40 139.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN87526.1 - 7.5e-41 140.1 0.0 1.1e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1206 PF06724.11 RLN87526.1 - 0.00062 19.8 3.8 7.7 6.7 0.1 5.1 4 1 2 6 6 6 1 Domain of Unknown Function (DUF1206) Kdo PF06293.14 RLN87526.1 - 0.0016 17.9 0.0 0.0072 15.7 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN87526.1 - 0.0017 17.8 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF4355 PF14265.6 RLN87526.1 - 0.0018 18.5 1.1 40 4.5 0.0 5.3 3 2 3 6 6 6 0 Domain of unknown function (DUF4355) DUF521 PF04412.13 RLN87526.1 - 0.03 13.1 0.0 0.049 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) 3HCDH_RFF PF18321.1 RLN87526.1 - 0.056 13.9 5.4 86 3.7 0.0 6.6 7 2 2 9 9 9 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain PilZ_2 PF16823.5 RLN87526.1 - 0.47 10.6 5.9 2.9 8.1 0.1 3.9 2 1 2 5 5 5 0 Atypical PilZ domain, cyclic di-GMP receptor 5_nucleotid PF05761.14 RLN87529.1 - 2e-28 99.6 0.5 9.5e-23 80.8 0.0 2.0 2 0 0 2 2 2 2 5' nucleotidase family DUF4162 PF13732.6 RLN87530.1 - 0.027 15.2 0.1 2.4 8.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) EF-hand_7 PF13499.6 RLN87531.1 - 1.7e-21 76.4 1.2 2.8e-11 43.7 0.0 3.5 3 1 0 3 3 3 2 EF-hand domain pair fn3 PF00041.21 RLN87531.1 - 1.5e-20 73.3 0.0 1.9e-05 24.9 0.0 5.2 5 0 0 5 5 5 4 Fibronectin type III domain EF-hand_1 PF00036.32 RLN87531.1 - 2.4e-19 67.3 4.9 6.1e-06 25.4 0.7 4.6 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 RLN87531.1 - 1.2e-16 59.4 6.2 2e-05 23.8 0.4 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RLN87531.1 - 1.2e-14 53.8 3.6 0.00069 19.4 0.0 4.9 4 1 1 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.6 RLN87531.1 - 5.2e-14 50.9 7.0 0.0018 18.0 0.1 5.2 5 0 0 5 5 5 3 EF-hand domain Pur_ac_phosph_N PF16656.5 RLN87531.1 - 3.1e-08 34.1 0.0 0.35 11.4 0.0 5.0 5 0 0 5 5 5 2 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 RLN87531.1 - 0.0021 18.4 0.0 1.4 9.3 0.0 4.0 4 0 0 4 4 4 1 Uncharacterised conserved protein (DUF2369) Methyltransf_11 PF08241.12 RLN87532.1 - 5.1e-19 68.7 0.6 7.4e-14 52.2 0.1 3.0 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 RLN87532.1 - 4.9e-18 65.6 0.6 9.2e-13 48.7 0.1 3.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 RLN87532.1 - 1.7e-14 54.4 0.2 7e-08 33.1 0.0 4.4 4 1 0 4 4 4 2 Methyltransferase domain Methyltransf_31 PF13847.6 RLN87532.1 - 2.1e-12 47.1 0.0 1e-09 38.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 RLN87532.1 - 1.6e-07 31.3 0.1 0.006 16.4 0.1 2.8 2 1 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 RLN87532.1 - 2e-06 27.5 1.3 0.0056 16.2 0.0 3.0 3 1 0 3 3 3 2 Methyltransferase small domain Ubie_methyltran PF01209.18 RLN87532.1 - 0.0001 21.7 0.0 0.0012 18.2 0.0 2.6 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family Spermine_synth PF01564.17 RLN87532.1 - 0.00027 20.4 0.0 0.0027 17.1 0.0 2.4 2 1 1 3 3 3 1 Spermine/spermidine synthase domain SR-25 PF10500.9 RLN87532.1 - 0.023 14.3 2.3 0.044 13.4 2.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MIP PF00230.20 RLN87533.1 - 9.2e-57 192.4 6.1 1.2e-56 192.0 6.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein Polysacc_synt_C PF14667.6 RLN87533.1 - 0.00013 22.1 10.0 0.41 10.7 2.2 3.3 3 1 0 3 3 3 3 Polysaccharide biosynthesis C-terminal domain Phage_holin_8 PF16931.5 RLN87533.1 - 0.068 13.2 0.1 0.41 10.6 0.0 2.1 2 0 0 2 2 2 0 Putative phage holin DUF4064 PF13273.6 RLN87533.1 - 2.2 8.6 6.2 0.74 10.1 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) MIP PF00230.20 RLN87534.1 - 2.4e-54 184.4 4.2 3.3e-54 184.0 4.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF417 PF04224.12 RLN87534.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF417 Phage_holin_8 PF16931.5 RLN87534.1 - 0.023 14.7 0.1 0.058 13.4 0.1 1.6 1 0 0 1 1 1 0 Putative phage holin DUF4064 PF13273.6 RLN87534.1 - 0.88 9.9 4.4 0.76 10.1 0.8 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) MIP PF00230.20 RLN87535.1 - 7.7e-54 182.8 5.7 1e-53 182.4 5.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 RLN87536.1 - 9.1e-51 172.7 13.3 1.1e-50 172.4 13.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 RLN87537.1 - 7e-39 133.9 10.5 8.6e-39 133.6 10.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 RLN87538.1 - 1.6e-54 185.0 6.2 2e-54 184.7 6.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein GAS PF13851.6 RLN87539.1 - 2.5e-27 95.6 5.1 3.7e-27 95.0 5.1 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Transcrip_act PF04949.13 RLN87539.1 - 0.0014 18.5 0.6 0.002 18.1 0.6 1.2 1 0 0 1 1 1 1 Transcriptional activator IFT20 PF14931.6 RLN87539.1 - 0.034 14.3 2.5 4.3 7.5 0.9 2.3 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Pilus_CpaD PF09476.10 RLN87539.1 - 0.07 12.9 0.1 0.23 11.1 0.1 1.8 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) DUF2203 PF09969.9 RLN87539.1 - 0.14 12.9 2.1 3.6 8.3 0.5 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) CENP-F_leu_zip PF10473.9 RLN87539.1 - 0.19 11.8 4.8 1.1 9.2 2.0 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WD40 PF00400.32 RLN87540.1 - 0.00015 22.4 5.5 0.0099 16.7 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 RLN87540.1 - 0.13 12.3 0.1 31 4.7 0.1 2.8 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PDEase_I PF00233.19 RLN87541.1 - 4.9e-50 170.5 0.0 3.2e-49 167.8 0.0 2.0 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 RLN87541.1 - 1.5e-21 77.4 8.4 1.2e-05 26.0 0.0 5.5 4 1 0 4 4 4 4 GAF domain GAF_2 PF13185.6 RLN87541.1 - 2.6e-17 63.4 12.6 2e-05 24.9 0.1 5.7 5 1 0 5 5 5 4 GAF domain GAF_3 PF13492.6 RLN87541.1 - 5.1e-14 52.7 4.9 0.00017 21.9 0.1 4.3 4 0 0 4 4 4 3 GAF domain Copine PF07002.16 RLN87542.1 - 6.2e-29 101.0 0.1 4.1e-20 72.2 0.0 2.5 2 1 0 2 2 2 2 Copine Metallophos PF00149.28 RLN87545.1 - 5.8e-13 49.8 0.5 1e-12 49.0 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 RLN87545.1 - 2.3e-06 28.1 1.0 1e-05 26.0 1.0 2.2 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 RLN87545.1 - 9.5e-05 23.2 2.3 0.00022 22.0 0.2 2.7 3 0 0 3 3 3 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 RLN87545.1 - 0.00032 21.0 0.0 0.047 13.9 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Copine PF07002.16 RLN87546.1 - 4e-52 176.8 0.0 1.6e-36 125.9 0.0 2.0 2 0 0 2 2 2 2 Copine vWA-TerF-like PF10138.9 RLN87546.1 - 2.2e-08 34.5 0.0 0.00028 21.1 0.0 2.2 2 0 0 2 2 2 2 vWA found in TerF C terminus VWA PF00092.28 RLN87546.1 - 0.043 14.1 0.0 0.06 13.6 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain MMPL PF03176.15 RLN87546.1 - 0.06 12.3 0.2 0.082 11.8 0.2 1.1 1 0 0 1 1 1 0 MMPL family Copine PF07002.16 RLN87547.1 - 1.3e-54 185.0 0.0 1.7e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 RLN87547.1 - 1.9e-10 41.2 0.0 2.9e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus Metallophos PF00149.28 RLN87548.1 - 1.8e-10 41.6 1.0 3.1e-10 40.9 1.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 RLN87548.1 - 5.2e-05 24.0 2.2 0.00014 22.6 0.2 2.8 3 0 0 3 3 3 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 RLN87548.1 - 5.4e-05 23.7 1.0 5.4e-05 23.7 1.0 2.5 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 RLN87548.1 - 0.0041 17.3 0.1 0.34 11.1 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain dsrm PF00035.26 RLN87550.1 - 0.00013 22.6 0.1 0.00029 21.5 0.1 1.7 1 1 0 1 1 1 1 Double-stranded RNA binding motif DUF1036 PF06282.11 RLN87550.1 - 0.0077 16.7 0.4 0.0093 16.5 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1036) DND1_DSRM PF14709.7 RLN87550.1 - 0.095 13.0 0.1 0.18 12.1 0.1 1.5 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 PDDEXK_9 PF08011.11 RLN87552.1 - 0.016 15.1 2.0 0.025 14.5 0.7 2.0 1 1 1 2 2 2 0 PD-(D/E)XK nuclease superfamily MPP6 PF10175.9 RLN87552.1 - 0.027 15.0 1.8 0.045 14.3 1.8 1.4 1 0 0 1 1 1 0 M-phase phosphoprotein 6 YccJ PF13993.6 RLN87552.1 - 0.079 13.3 0.1 0.76 10.2 0.0 2.5 3 0 0 3 3 3 0 YccJ-like protein Scramblase PF03803.15 RLN87553.1 - 2.1e-12 46.8 0.0 8e-05 22.0 0.0 3.2 3 1 0 3 3 3 3 Scramblase IMUP PF15761.5 RLN87555.1 - 6.7 7.5 17.0 0.48 11.2 10.2 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein Methyltransf_16 PF10294.9 RLN87556.1 - 0.093 12.5 0.1 1.4 8.6 0.2 2.0 1 1 1 2 2 2 0 Lysine methyltransferase SEEEED PF14797.6 RLN87557.1 - 0.006 16.7 9.2 0.011 15.9 9.2 1.3 1 0 0 1 1 1 1 Serine-rich region of AP3B1, clathrin-adaptor complex DHR10 PF18595.1 RLN87557.1 - 0.013 15.5 2.0 1.8 8.7 0.0 3.4 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain DUF755 PF05501.11 RLN87557.1 - 0.24 11.7 2.8 0.61 10.4 2.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF755) LisH PF08513.11 RLN87558.1 - 1.1e-06 28.4 0.2 6.3e-06 26.0 0.0 2.5 2 0 0 2 2 2 1 LisH Nop14 PF04147.12 RLN87558.1 - 0.4 8.8 24.5 0.17 10.0 21.5 1.7 2 0 0 2 2 2 0 Nop14-like family Peroxidase_2 PF01328.17 RLN87559.1 - 5.4e-48 164.0 0.0 6.3e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 NUP50 PF08911.11 RLN87559.1 - 0.09 13.5 0.0 0.16 12.7 0.0 1.4 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) p450 PF00067.22 RLN87560.1 - 1.7e-70 238.1 0.0 1.9e-70 237.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peroxidase_2 PF01328.17 RLN87561.1 - 2.9e-47 161.6 0.0 3.6e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Peroxidase_2 PF01328.17 RLN87562.1 - 4.1e-48 164.4 0.0 5.3e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Sec1 PF00995.23 RLN87563.1 - 1.3e-53 183.2 0.0 1.5e-53 183.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SLX9 PF15341.6 RLN87563.1 - 0.62 10.5 3.2 3.8 7.9 2.5 2.2 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 DUF2514 PF10721.9 RLN87563.1 - 4 7.5 6.2 15 5.5 0.5 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2514) EF-hand_8 PF13833.6 RLN87564.1 - 1.3e-36 124.2 7.4 3.1e-09 36.5 0.0 5.7 5 0 0 5 5 5 5 EF-hand domain pair EF-hand_1 PF00036.32 RLN87564.1 - 1.2e-16 58.9 17.6 3.7e-05 23.0 0.2 6.4 7 0 0 7 7 7 4 EF hand EF-hand_7 PF13499.6 RLN87564.1 - 1.2e-15 57.7 14.6 0.00031 21.1 0.3 6.2 5 2 1 6 6 6 5 EF-hand domain pair EF-hand_6 PF13405.6 RLN87564.1 - 4.2e-13 48.1 30.4 0.0022 17.8 0.1 8.9 11 0 0 11 11 11 4 EF-hand domain EF-hand_5 PF13202.6 RLN87564.1 - 4.1e-08 32.4 17.9 0.0014 18.0 0.3 4.8 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.7 RLN87564.1 - 0.006 16.5 0.4 22 5.1 0.1 3.6 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand FidL_like PF15941.5 RLN87564.1 - 0.1 13.0 1.7 0.71 10.4 0.5 2.5 2 0 0 2 2 2 0 FidL-like putative membrane protein BssS PF13991.6 RLN87564.1 - 0.12 12.4 0.2 5.7 7.1 0.1 2.6 2 0 0 2 2 2 0 BssS protein family Ubie_methyltran PF01209.18 RLN87565.1 - 2.2e-83 279.2 0.0 2.8e-83 278.8 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 RLN87565.1 - 2.3e-18 66.6 0.1 6.6e-18 65.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN87565.1 - 5e-18 65.6 0.1 2.2e-17 63.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN87565.1 - 1.1e-12 48.5 0.0 2.1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN87565.1 - 7.8e-12 45.2 0.0 1.3e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN87565.1 - 9.7e-09 35.3 0.0 1.2e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 RLN87565.1 - 0.0017 18.3 0.0 0.0062 16.4 0.0 1.9 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_32 PF13679.6 RLN87565.1 - 0.2 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TPR_1 PF00515.28 RLN87566.1 - 1.7e-113 366.3 29.8 5.8e-10 38.6 0.0 13.2 13 0 0 13 13 13 13 Tetratricopeptide repeat TPR_2 PF07719.17 RLN87566.1 - 1.7e-91 293.1 38.6 2.4e-08 33.5 0.1 13.4 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_11 PF13414.6 RLN87566.1 - 2.7e-78 257.4 37.9 9.5e-09 34.8 0.5 13.3 3 2 10 13 13 13 12 TPR repeat TPR_8 PF13181.6 RLN87566.1 - 4.3e-67 216.8 15.2 1.5e-05 24.9 0.0 13.3 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_17 PF13431.6 RLN87566.1 - 2.6e-65 212.2 28.3 5e-06 26.5 0.0 14.3 14 0 0 14 14 14 11 Tetratricopeptide repeat TPR_16 PF13432.6 RLN87566.1 - 2.3e-52 175.3 46.8 5.4e-10 39.8 0.6 8.5 5 2 4 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.6 RLN87566.1 - 9.6e-42 141.2 40.7 3.7e-09 36.7 0.4 9.7 3 3 7 10 10 10 10 Tetratricopeptide repeat TPR_9 PF13371.6 RLN87566.1 - 1.4e-39 134.1 30.6 2.7e-09 37.1 0.6 9.6 3 3 8 11 11 11 11 Tetratricopeptide repeat TPR_7 PF13176.6 RLN87566.1 - 3.7e-29 98.6 37.6 0.0064 16.4 0.1 13.2 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_14 PF13428.6 RLN87566.1 - 9.1e-27 91.5 36.1 0.028 15.2 0.0 13.1 2 2 11 13 13 13 7 Tetratricopeptide repeat TPR_19 PF14559.6 RLN87566.1 - 5.3e-26 90.9 31.1 0.00015 22.2 0.3 9.5 5 3 5 10 10 10 8 Tetratricopeptide repeat TPR_6 PF13174.6 RLN87566.1 - 8.3e-25 85.7 36.3 0.13 13.0 0.2 13.3 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_10 PF13374.6 RLN87566.1 - 8.3e-21 73.2 43.3 0.0015 18.3 0.9 11.7 12 0 0 12 12 12 7 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN87566.1 - 3.3e-16 59.3 23.9 0.0043 17.2 0.3 7.6 2 2 7 9 9 9 7 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 RLN87566.1 - 1.5e-14 53.2 27.3 0.12 11.8 0.0 11.8 13 0 0 13 13 12 5 SHNi-TPR Fis1_TPR_C PF14853.6 RLN87566.1 - 1.8e-08 34.3 18.3 0.014 15.4 0.2 8.6 8 1 1 9 9 9 2 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 RLN87566.1 - 1.4e-06 28.5 11.5 9.6 6.3 0.0 8.9 3 2 5 9 9 9 0 Domain of Unknown Function (DUF3856) BTAD PF03704.17 RLN87566.1 - 1.8e-06 28.5 21.3 0.076 13.5 2.2 5.7 2 1 3 5 5 5 3 Bacterial transcriptional activator domain TPR_4 PF07721.14 RLN87566.1 - 4.9e-06 26.7 6.1 25 5.9 0.0 8.6 9 0 0 9 9 9 0 Tetratricopeptide repeat NARP1 PF12569.8 RLN87566.1 - 7.6e-06 25.1 16.8 0.024 13.5 0.1 6.0 2 2 4 6 6 6 3 NMDA receptor-regulated protein 1 MIT PF04212.18 RLN87566.1 - 1.6e-05 24.9 25.5 0.24 11.5 0.0 9.2 10 1 0 10 10 10 2 MIT (microtubule interacting and transport) domain TPR_5 PF12688.7 RLN87566.1 - 0.00092 19.4 17.0 2.5 8.4 0.3 5.8 3 1 1 5 5 5 1 Tetratrico peptide repeat TPR_20 PF14561.6 RLN87566.1 - 0.028 14.8 19.6 1.4 9.3 0.7 6.3 5 1 1 6 6 6 0 Tetratricopeptide repeat CSN5_C PF18323.1 RLN87566.1 - 1 10.4 10.1 6 7.9 1.6 3.8 4 0 0 4 4 3 0 Cop9 signalosome subunit 5 C-terminal domain Strep_SA_rep PF06696.11 RLN87566.1 - 9.9 6.3 8.4 84 3.3 0.3 4.7 5 0 0 5 5 4 0 Streptococcal surface antigen repeat HA2 PF04408.23 RLN87569.1 - 1.9e-08 34.5 0.0 6.7e-08 32.8 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) RHD3 PF05879.12 RLN87570.1 - 2e-06 26.3 8.2 2.8e-06 25.8 0.1 2.9 2 1 0 3 3 3 2 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 RLN87570.1 - 0.00011 21.5 0.1 0.00022 20.6 0.1 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 RLN87570.1 - 0.0041 17.2 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Cadherin_3 PF16184.5 RLN87571.1 - 0.0024 17.9 1.5 0.95 9.5 0.2 5.2 6 0 0 6 6 6 1 Cadherin-like YchF-GTPase_C PF06071.13 RLN87571.1 - 0.0048 17.1 0.0 6.6 7.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF933) DUF4762 PF15959.5 RLN87571.1 - 0.031 14.3 0.0 16 5.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4762) sCache_3_2 PF17203.4 RLN87571.1 - 0.047 13.8 3.3 6.4 6.9 0.1 3.2 3 0 0 3 3 3 0 Single cache domain 3 TP6A_N PF04406.14 RLN87571.1 - 0.14 12.1 3.8 10 6.2 0.3 2.5 2 0 0 2 2 2 0 Type IIB DNA topoisomerase Dynein_C PF18199.1 RLN87573.1 - 1.1e-86 290.9 0.1 1.2e-86 290.7 0.1 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 RLN87573.1 - 2.9e-13 50.0 0.0 5.3e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain TPR_1 PF00515.28 RLN87574.1 - 5.5e-12 45.0 6.6 0.00063 19.5 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN87574.1 - 2.8e-11 42.6 7.2 0.0018 18.2 0.7 4.2 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN87574.1 - 4.4e-07 29.5 1.8 0.002 17.8 0.1 2.7 2 0 0 2 2 2 2 TPR repeat TPR_19 PF14559.6 RLN87574.1 - 4.1e-06 27.2 5.9 1.6e-05 25.3 0.5 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN87574.1 - 2.3e-05 24.5 1.0 0.055 13.9 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN87574.1 - 0.00015 21.7 5.4 0.88 9.9 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN87574.1 - 0.0077 16.4 6.6 0.0079 16.3 3.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN87574.1 - 0.013 16.1 13.2 0.018 15.7 0.1 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN87574.1 - 0.018 15.3 3.8 0.069 13.4 3.8 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 RLN87574.1 - 0.059 13.7 8.9 0.042 14.1 1.7 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 RLN87574.1 - 0.068 13.2 3.6 7 6.9 0.2 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN87574.1 - 0.61 11.1 5.9 31 5.7 0.0 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF501 PF04417.12 RLN87575.1 - 2.9e-37 127.6 0.1 4.6e-37 126.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF501) Birna_VP5 PF03042.14 RLN87575.1 - 0.082 12.9 0.6 0.14 12.2 0.6 1.4 1 0 0 1 1 1 0 Birnavirus VP5 protein Ras PF00071.22 RLN87576.1 - 4.7e-54 182.3 0.0 8.8e-54 181.5 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN87576.1 - 2.1e-29 102.2 0.0 4.6e-29 101.1 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Autophagy_N PF03986.13 RLN87576.1 - 2.7e-20 72.7 0.2 2.4e-19 69.6 0.0 2.5 3 0 0 3 3 3 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 RLN87576.1 - 1.1e-18 67.5 0.3 4.9e-18 65.5 0.2 2.2 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 RLN87576.1 - 2.5e-14 52.5 3.0 4.4e-14 51.7 3.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Arf PF00025.21 RLN87576.1 - 5e-11 42.4 0.0 7.5e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RLN87576.1 - 9.1e-05 22.5 0.0 0.00018 21.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RLN87576.1 - 0.0015 18.1 0.0 0.011 15.3 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF4034 PF13226.6 RLN87576.1 - 0.017 14.5 0.2 0.074 12.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4034) Gtr1_RagA PF04670.12 RLN87576.1 - 0.02 14.2 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 RLN87576.1 - 0.11 12.4 0.0 2.2 8.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase DUF2857 PF11198.8 RLN87577.1 - 0.41 10.4 2.3 1.8 8.3 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2857) Ank_4 PF13637.6 RLN87578.1 - 4e-10 40.0 0.5 8.7e-06 26.2 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN87578.1 - 8.2e-08 32.7 0.0 2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN87578.1 - 2.9e-07 30.6 0.3 6.6e-07 29.5 0.3 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 RLN87578.1 - 1e-05 25.7 1.0 0.0025 18.2 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 RLN87578.1 - 2.7e-05 24.2 0.7 0.0038 17.6 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Atg14 PF10186.9 RLN87578.1 - 0.1 11.7 17.6 0.24 10.4 17.6 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APC1_C PF18122.1 RLN87578.1 - 0.78 9.7 5.8 2.6 8.0 2.9 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex sub unit 1 C-terminal domain Mito_carr PF00153.27 RLN87580.1 - 1.9e-48 162.3 4.7 1.4e-16 60.1 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein MIF4G PF02854.19 RLN87580.1 - 1.3e-44 152.4 1.0 1.3e-18 67.4 0.2 4.3 3 1 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 RLN87580.1 - 4.3e-13 50.2 0.6 4.3e-13 50.2 0.6 2.5 2 0 0 2 2 2 1 Up-frameshift suppressor 2 Nop14 PF04147.12 RLN87580.1 - 0.021 13.1 4.6 0.06 11.6 4.6 1.7 1 0 0 1 1 1 0 Nop14-like family Elicitin PF00964.17 RLN87581.1 - 8.8e-23 80.2 3.1 1.4e-22 79.6 3.1 1.3 1 0 0 1 1 1 1 Elicitin DUF2541 PF10807.8 RLN87581.1 - 0.088 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2541) DUF726 PF05277.12 RLN87582.1 - 1.1e-15 57.5 0.0 2.9e-10 39.6 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF726) DUF676 PF05057.14 RLN87582.1 - 0.028 13.9 0.0 0.13 11.8 0.0 1.9 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 RLN87582.1 - 0.074 12.9 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) TPR_19 PF14559.6 RLN87583.1 - 2.8e-09 37.4 1.1 3.4e-07 30.7 0.1 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN87583.1 - 1.2e-07 31.9 0.6 0.3 12.0 0.5 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN87583.1 - 2.2e-07 30.5 0.0 0.1 12.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN87583.1 - 1.4e-06 27.8 0.0 0.026 14.3 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN87583.1 - 1.5e-05 25.0 0.0 0.0069 16.7 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN87583.1 - 0.00028 21.1 2.0 0.027 14.7 0.0 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 RLN87583.1 - 0.00062 19.6 0.0 0.71 10.0 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN87583.1 - 0.012 15.8 1.2 0.034 14.3 0.4 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat efb-c PF12199.8 RLN87583.1 - 0.043 13.9 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 Extracellular fibrinogen binding protein C terminal TPR_16 PF13432.6 RLN87583.1 - 0.38 11.5 4.1 15 6.4 0.1 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat ParcG PF10274.9 RLN87584.1 - 2.4e-63 213.6 0.0 5.6e-34 117.9 0.0 2.9 2 1 0 2 2 2 2 Parkin co-regulated protein LRR_6 PF13516.6 RLN87585.1 - 7.5e-15 53.7 18.1 0.0036 17.2 0.0 9.3 11 0 0 11 11 11 4 Leucine Rich repeat LRR_4 PF12799.7 RLN87585.1 - 1.1e-08 35.3 4.4 0.055 13.9 0.0 6.6 5 3 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN87585.1 - 0.074 13.6 7.6 81 4.4 0.0 7.0 9 1 0 9 9 9 0 Leucine Rich Repeat DUF2205 PF10224.9 RLN87586.1 - 0.028 14.4 9.6 0.048 13.7 0.7 3.4 3 0 0 3 3 3 0 Short coiled-coil protein Prefoldin_2 PF01920.20 RLN87586.1 - 0.029 14.3 4.8 0.26 11.3 4.8 2.4 1 1 0 1 1 1 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 RLN87586.1 - 0.064 13.3 0.6 0.064 13.3 0.6 2.9 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 RLN87586.1 - 0.15 11.1 9.0 0.24 10.4 9.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 RLN87586.1 - 0.16 12.0 0.2 0.16 12.0 0.2 2.8 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 RLN87586.1 - 1.4 9.5 15.5 1.3 9.5 1.3 2.8 2 2 0 2 2 2 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 RLN87586.1 - 1.9 8.7 19.4 0.42 10.8 4.7 3.0 3 1 0 3 3 3 0 JNK_SAPK-associated protein-1 THOC7 PF05615.13 RLN87586.1 - 2.2 8.6 12.9 0.42 10.9 1.3 2.6 2 0 0 2 2 2 0 Tho complex subunit 7 UPF0449 PF15136.6 RLN87586.1 - 2.7 8.5 7.4 0.47 11.0 0.2 3.0 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 SPRY PF00622.28 RLN87589.1 - 2.5e-06 27.6 0.0 1.2e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 SPRY domain Phage_integrase PF00589.22 RLN87591.1 - 0.00058 19.7 0.1 0.0013 18.6 0.1 1.6 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 RLN87591.1 - 0.09 13.1 0.2 4 7.8 0.1 2.8 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Phage_integrase PF00589.22 RLN87592.1 - 0.0098 15.7 0.0 0.019 14.8 0.0 1.5 1 1 0 1 1 1 1 Phage integrase family DUF1265 PF06887.14 RLN87593.1 - 0.12 12.3 1.5 1 9.4 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1265) HLH PF00010.26 RLN87594.1 - 6.1e-09 35.7 1.5 1e-08 35.0 1.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PseudoU_synth_1 PF01416.20 RLN87595.1 - 1.2e-29 102.9 0.0 8.6e-17 61.6 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase ANAPC4_WD40 PF12894.7 RLN87597.1 - 5.4e-11 42.6 0.0 0.0041 17.4 0.0 6.8 7 1 1 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RLN87597.1 - 0.013 16.3 0.7 33 5.6 0.0 5.7 5 0 0 5 5 5 0 WD domain, G-beta repeat SLATT_1 PF18181.1 RLN87597.1 - 0.026 14.4 0.4 0.061 13.3 0.4 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 PDZ PF00595.24 RLN87597.1 - 0.032 14.6 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 RLN87597.1 - 0.051 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Synaptobrevin PF00957.21 RLN87597.1 - 0.057 13.2 0.5 0.12 12.2 0.5 1.5 1 0 0 1 1 1 0 Synaptobrevin RVT_3 PF13456.6 RLN87598.1 - 2.8e-24 85.3 0.2 3.6e-24 84.9 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 RLN87598.1 - 8.2e-13 48.8 0.1 1.6e-12 47.8 0.1 1.5 1 1 0 1 1 1 1 RNase H Med30 PF11315.8 RLN87598.1 - 0.065 13.4 0.2 0.08 13.1 0.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 30 Dimer_Tnp_hAT PF05699.14 RLN87599.1 - 0.01 15.6 0.0 0.055 13.3 0.0 2.1 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region DDE_3 PF13358.6 RLN87599.1 - 0.13 12.1 0.1 0.95 9.2 0.1 2.6 2 2 0 2 2 2 0 DDE superfamily endonuclease RabGAP-TBC PF00566.18 RLN87601.1 - 4.9e-25 88.4 0.2 5.8e-21 75.1 0.3 2.2 1 1 1 2 2 2 2 Rab-GTPase-TBC domain DUF4864 PF16156.5 RLN87601.1 - 0.1 13.3 0.0 0.24 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) Dynein_C PF18199.1 RLN87602.1 - 5.7e-83 278.6 0.0 7.8e-83 278.2 0.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 RLN87602.1 - 9.1e-53 178.4 0.0 1.3e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RLN87602.1 - 7.7e-27 93.8 0.1 1.7e-26 92.7 0.1 1.6 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain LicD PF04991.13 RLN87603.1 - 0.00025 21.3 0.1 0.023 14.8 0.0 2.2 2 0 0 2 2 2 2 LicD family 7TM_GPCR_Srw PF10324.9 RLN87603.1 - 0.11 11.8 0.1 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw SPA PF08616.10 RLN87604.1 - 2.7e-29 101.4 0.0 6.9e-29 100.1 0.0 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 RLN87604.1 - 9.4e-14 52.0 0.0 2e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2347 PF09804.9 RLN87604.1 - 2.3e-13 50.4 0.0 8.5e-13 48.5 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 RLN87604.1 - 1.6e-10 40.3 0.0 0.00031 19.6 0.0 3.0 1 1 1 2 2 2 2 Transport protein Avl9 LicD PF04991.13 RLN87604.1 - 0.02 15.1 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 LicD family DEC-1_N PF04625.13 RLN87605.1 - 0.018 14.1 1.3 0.023 13.7 1.3 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF4518 PF15008.6 RLN87610.1 - 0.0011 18.2 0.2 0.0012 18.1 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) Myosin_head PF00063.21 RLN87611.1 - 5.4e-221 735.4 0.0 7.7e-221 734.9 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Aida_C2 PF14186.6 RLN87611.1 - 2.8e-31 108.1 0.0 3.8e-16 59.0 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal adhesion Ank_2 PF12796.7 RLN87611.1 - 1.3e-19 70.5 0.7 3.9e-08 33.8 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN87611.1 - 1.3e-16 60.7 0.4 2.2e-08 34.5 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) IQ PF00612.27 RLN87611.1 - 4.5e-16 57.1 104.8 0.0034 17.0 0.6 16.0 16 0 0 16 16 16 9 IQ calmodulin-binding motif Ank_3 PF13606.6 RLN87611.1 - 6.4e-16 56.8 0.3 0.0033 17.8 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 RLN87611.1 - 8.5e-16 57.8 3.0 5.2e-07 29.8 0.1 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN87611.1 - 1.1e-14 54.1 0.3 0.0048 17.3 0.0 4.1 4 0 0 4 4 3 3 Ankyrin repeat PH PF00169.29 RLN87611.1 - 8.4e-14 52.0 0.1 2.6e-13 50.4 0.1 2.0 1 0 0 1 1 1 1 PH domain Myosin_N PF02736.19 RLN87611.1 - 3.1e-05 23.7 2.4 4.5e-05 23.2 0.2 2.3 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_18 PF13238.6 RLN87611.1 - 0.18 12.4 1.0 1.9 9.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 RLN87611.1 - 0.24 11.8 1.7 0.4 11.0 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain PH_11 PF15413.6 RLN87611.1 - 0.27 11.7 1.4 1.5 9.3 0.2 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain TTL PF03133.15 RLN87612.1 - 1.5e-52 178.5 0.0 2e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RLN87612.1 - 1.4e-05 24.5 0.0 0.046 13.0 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 RLN87612.1 - 0.0016 18.5 0.0 0.22 11.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain PAP_assoc PF03828.19 RLN87613.1 - 8.4e-16 57.9 0.0 1.7e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase zf-CCHC PF00098.23 RLN87613.1 - 0.0013 18.7 2.4 0.0013 18.7 2.4 3.5 4 0 0 4 4 4 2 Zinc knuckle zf-C2H2_10 PF16588.5 RLN87613.1 - 0.07 12.9 0.5 0.2 11.4 0.5 1.7 1 0 0 1 1 1 0 C2H2 zinc-finger Brix PF04427.18 RLN87614.1 - 1.6e-15 57.7 0.0 8.3e-12 45.6 0.1 2.2 1 1 1 2 2 2 2 Brix domain Cleaved_Adhesin PF07675.11 RLN87614.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Cleaved Adhesin Domain WD40 PF00400.32 RLN87615.1 - 1.2e-05 26.0 0.1 0.0098 16.7 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat eIF2A PF08662.11 RLN87615.1 - 0.12 12.2 0.0 4.6 7.1 0.0 2.8 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A AMP-binding PF00501.28 RLN87616.1 - 1.9e-20 72.9 0.3 3.3e-20 72.1 0.3 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN87616.1 - 5.4e-05 24.1 0.0 0.00011 23.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain T2SS-T3SS_pil_N PF13629.6 RLN87616.1 - 0.055 13.2 0.8 0.21 11.3 0.0 2.3 2 0 0 2 2 2 0 Pilus formation protein N terminal region AF-4 PF05110.13 RLN87617.1 - 0.0035 15.5 21.1 0.0043 15.3 21.1 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Hamartin PF04388.12 RLN87617.1 - 8.9 4.8 8.2 10 4.6 8.2 1.0 1 0 0 1 1 1 0 Hamartin protein MMR_HSR1_Xtn PF16897.5 RLN87618.1 - 1.3e-38 131.2 0.0 2.3e-38 130.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 RLN87618.1 - 1.7e-10 41.0 0.0 1.1e-09 38.4 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 RLN87618.1 - 1e-08 35.1 0.0 2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain Dynamin_N PF00350.23 RLN87618.1 - 0.0012 19.0 0.4 0.0025 17.9 0.0 1.7 2 0 0 2 2 2 1 Dynamin family Mito_carr PF00153.27 RLN87619.1 - 3.6e-36 123.0 0.8 4.8e-25 87.3 0.2 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein TAL_FSA PF00923.19 RLN87620.1 - 2e-102 342.4 0.1 2.4e-102 342.2 0.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase aGPT-Pplase1 PF18723.1 RLN87621.1 - 1.6e-11 44.2 0.6 3.3e-11 43.1 0.2 1.6 1 1 1 2 2 2 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 PHD PF00628.29 RLN87621.1 - 6.6e-10 38.7 8.2 6.6e-10 38.7 8.2 2.4 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.6 RLN87621.1 - 5.7e-05 22.6 2.1 5.7e-05 22.6 2.1 2.4 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 RLN87621.1 - 0.0022 17.9 1.7 0.0022 17.9 1.7 3.2 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 RLN87621.1 - 0.0088 15.7 1.2 0.0088 15.7 1.2 2.3 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain DUF4953 PF16313.5 RLN87621.1 - 0.065 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Met-zincin C1_2 PF03107.16 RLN87621.1 - 0.12 12.7 10.7 0.085 13.2 2.8 4.0 4 0 0 4 4 4 0 C1 domain DUF2116 PF09889.9 RLN87621.1 - 0.57 10.2 10.3 0.84 9.7 0.3 3.6 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) zf-RING_9 PF13901.6 RLN87621.1 - 0.7 9.8 12.7 0.19 11.7 5.7 2.5 2 1 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD_4 PF16866.5 RLN87621.1 - 1 9.5 21.7 3.4 7.8 10.5 3.9 3 1 0 3 3 3 0 PHD-finger C1_1 PF00130.22 RLN87621.1 - 2.6 8.0 10.3 0.21 11.5 2.3 3.0 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Vps51 PF08700.11 RLN87622.1 - 3.6e-05 23.7 2.4 4e-05 23.6 0.4 2.2 2 0 0 2 2 2 1 Vps51/Vps67 PIP5K PF01504.18 RLN87624.1 - 2.6e-39 135.1 0.1 1.6e-34 119.4 0.0 2.1 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase TolA PF06519.11 RLN87627.1 - 0.15 12.3 0.0 0.42 10.8 0.0 1.7 1 0 0 1 1 1 0 TolA C-terminal Fascin PF06268.13 RLN87629.1 - 0.025 14.8 0.1 0.17 12.1 0.1 1.9 1 1 1 2 2 2 0 Fascin domain RXLR PF16810.5 RLN87631.1 - 0.017 15.5 0.2 0.017 15.5 0.2 2.4 2 1 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity PRTase_3 PF15610.6 RLN87631.1 - 0.16 11.1 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 PRTase ComF-like Guanylate_cyc PF00211.20 RLN87633.1 - 5.1e-15 55.6 0.0 8.3e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF1996 PF09362.10 RLN87634.1 - 4.7e-74 249.3 0.2 6.7e-74 248.8 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) ADH_zinc_N PF00107.26 RLN87634.1 - 5.4e-20 71.7 0.0 1e-19 70.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN87634.1 - 4.2e-14 53.8 0.0 1.1e-13 52.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN87634.1 - 0.00041 20.2 0.1 0.0022 17.8 0.1 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain HEV_ORF1 PF02444.16 RLN87634.1 - 1.3 9.7 7.6 19 5.9 8.3 2.7 2 1 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) PfkB PF00294.24 RLN87635.1 - 3.5e-56 190.7 0.6 3.9e-56 190.6 0.6 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 RLN87635.1 - 2.3e-09 37.0 0.0 4.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 RLN87635.1 - 0.019 14.4 0.1 0.039 13.4 0.1 1.4 1 1 0 1 1 1 0 Carbohydrate kinase PHO4 PF01384.20 RLN87637.1 - 1.8e-47 162.1 21.6 3e-47 161.3 21.6 1.3 1 0 0 1 1 1 1 Phosphate transporter family Colicin_im PF03857.13 RLN87637.1 - 0.11 12.4 3.7 0.26 11.3 3.7 1.6 1 0 0 1 1 1 0 Colicin immunity protein AC_N PF16214.5 RLN87637.1 - 0.36 9.9 4.9 0.054 12.6 0.7 1.7 1 1 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region PAE PF03283.13 RLN87638.1 - 3.1e-14 52.9 0.6 5.1e-14 52.2 0.6 1.2 1 0 0 1 1 1 1 Pectinacetylesterase PAE PF03283.13 RLN87639.1 - 2.1e-14 53.5 0.1 3.4e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 Pectinacetylesterase Abhydrolase_3 PF07859.13 RLN87639.1 - 0.11 12.3 0.1 0.58 10.0 0.0 2.3 2 1 0 2 2 2 0 alpha/beta hydrolase fold FHA PF00498.26 RLN87640.1 - 6.4e-05 23.2 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-C2H2_4 PF13894.6 RLN87640.1 - 0.057 14.3 0.6 0.2 12.6 0.6 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger HSP70 PF00012.20 RLN87641.1 - 1.3e-149 499.2 8.3 1.6e-149 498.9 8.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN87641.1 - 1.6e-15 56.8 0.1 3e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Big_3 PF07523.12 RLN87641.1 - 0.0011 19.3 0.1 0.0033 17.7 0.1 1.9 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 3) Yip1 PF04893.17 RLN87642.1 - 1.6e-06 28.0 13.3 2e-06 27.6 13.3 1.1 1 0 0 1 1 1 1 Yip1 domain DUF2070 PF09843.9 RLN87642.1 - 5.4 5.2 10.5 6.9 4.8 10.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ion_trans PF00520.31 RLN87643.1 - 0.1 11.8 7.9 0.15 11.3 7.9 1.3 1 0 0 1 1 1 0 Ion transport protein ResB PF05140.14 RLN87643.1 - 1.4 7.6 4.0 2.1 7.0 4.0 1.1 1 0 0 1 1 1 0 ResB-like family DUF3246 PF11596.8 RLN87644.1 - 0.086 12.3 4.5 0.11 11.9 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) T7SS_ESX_EspC PF10824.8 RLN87644.1 - 0.77 10.3 4.8 0.21 12.1 1.0 1.9 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm Adeno_terminal PF02459.15 RLN87644.1 - 8.3 4.7 11.9 18 3.5 11.9 1.5 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Sacchrp_dh_C PF16653.5 RLN87645.1 - 3.3e-86 289.7 0.0 5.2e-86 289.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 RLN87645.1 - 2.8e-28 98.9 0.0 6.6e-28 97.7 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 RLN87645.1 - 1.6e-17 63.9 0.4 4e-17 62.7 0.4 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Saccharop_dh_N PF04455.12 RLN87645.1 - 1.2e-10 41.7 0.1 2.7e-10 40.5 0.1 1.6 1 0 0 1 1 1 1 LOR/SDH bifunctional enzyme conserved region AlaDh_PNT_C PF01262.21 RLN87645.1 - 0.00018 20.9 0.0 0.053 12.8 0.0 2.8 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 RLN87645.1 - 0.096 12.7 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase YscJ_FliF_C PF08345.11 RLN87646.1 - 0.073 13.4 2.6 0.84 10.0 2.8 2.7 2 0 0 2 2 2 0 Flagellar M-ring protein C-terminal DYW_deaminase PF14432.6 RLN87648.1 - 5.4e-26 91.0 0.0 9e-26 90.2 0.0 1.3 1 0 0 1 1 1 1 DYW family of nucleic acid deaminases Methyltransf_16 PF10294.9 RLN87649.1 - 1.4e-24 86.7 0.0 1.8e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 RLN87649.1 - 4.5e-09 36.1 0.0 5.7e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 RLN87649.1 - 3e-07 30.1 0.0 4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 RLN87649.1 - 0.0006 20.5 0.0 0.0017 19.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 RLN87649.1 - 0.024 14.3 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 RLN87649.1 - 0.077 12.8 0.0 0.16 11.8 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 RLN87649.1 - 0.093 12.5 0.0 0.2 11.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 RLN87649.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Abhydrolase_1 PF00561.20 RLN87650.1 - 5.3e-07 29.5 0.0 0.029 14.0 0.0 3.1 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 RLN87650.1 - 5.2e-05 23.2 0.0 0.2 11.5 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN87650.1 - 5.5e-05 23.9 9.9 0.012 16.2 2.2 3.1 2 1 1 3 3 3 2 Alpha/beta hydrolase family DLH PF01738.18 RLN87650.1 - 0.0004 20.0 0.0 0.16 11.5 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Hydrolase_4 PF12146.8 RLN87650.1 - 0.0051 16.1 0.0 0.38 10.0 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 RLN87650.1 - 0.11 12.0 0.0 0.89 9.0 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Peptidase_C13 PF01650.18 RLN87651.1 - 1.1e-05 25.1 0.1 2.1e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Peptidase C13 family BSD PF03909.17 RLN87652.1 - 7.8e-13 48.2 6.7 4.4e-09 36.2 0.3 3.1 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 RLN87652.1 - 1e-10 41.8 0.0 1e-10 41.8 0.0 1.9 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain DUF2458 PF10454.9 RLN87652.1 - 0.0025 17.5 1.6 0.0029 17.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2458) MFS_1 PF07690.16 RLN87653.1 - 3e-18 65.9 19.2 3e-18 65.9 19.2 1.8 2 1 1 3 3 3 1 Major Facilitator Superfamily Phage_Mu_Gam PF07352.12 RLN87654.1 - 0.1 12.5 6.8 0.74 9.7 0.4 2.8 2 1 1 3 3 3 0 Bacteriophage Mu Gam like protein DUF1084 PF06454.11 RLN87655.1 - 1.9e-05 24.2 7.1 1.9e-05 24.2 7.1 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1084) Pkinase PF00069.25 RLN87658.1 - 1.9e-62 211.1 0.0 2.5e-62 210.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN87658.1 - 8.8e-37 126.8 0.0 1.4e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 RLN87658.1 - 0.0035 18.0 1.2 0.0064 17.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 RLN87658.1 - 0.015 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 RLN87658.1 - 0.031 13.1 0.0 0.066 12.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase DUF2855 PF11017.8 RLN87658.1 - 0.077 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) YrbL-PhoP_reg PF10707.9 RLN87658.1 - 0.2 11.2 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Glyco_hydro81C PF17652.1 RLN87659.1 - 4.1e-112 374.9 2.8 6.2e-112 374.3 2.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 RLN87659.1 - 2.2e-53 181.5 0.6 3.7e-53 180.8 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain DNA_pol_B_thumb PF14791.6 RLN87660.1 - 1.1e-19 70.3 0.0 3.3e-19 68.8 0.0 1.9 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 RLN87660.1 - 2.7e-18 65.5 0.0 7.3e-18 64.1 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda XK-related PF09815.9 RLN87660.1 - 9e-07 28.3 7.4 1.4e-06 27.7 7.4 1.2 1 0 0 1 1 1 1 XK-related protein HHH_8 PF14716.6 RLN87660.1 - 4.8e-05 23.6 0.0 0.28 11.6 0.0 3.4 3 0 0 3 3 3 2 Helix-hairpin-helix domain HHH_5 PF14520.6 RLN87660.1 - 0.0016 19.0 0.0 0.0055 17.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain Med1 PF10744.9 RLN87660.1 - 0.018 14.1 0.1 0.03 13.4 0.1 1.3 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 Cdd1 PF11731.8 RLN87660.1 - 0.019 15.2 0.0 0.049 13.9 0.0 1.7 1 0 0 1 1 1 0 Pathogenicity locus BRCT PF00533.26 RLN87660.1 - 0.037 14.4 0.0 0.097 13.1 0.0 1.8 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF2052 PF09747.9 RLN87660.1 - 0.94 9.6 13.1 1.7 8.7 13.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF2207 PF09972.9 RLN87660.1 - 6 5.5 7.0 0.55 8.9 2.2 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DNA_ligase_A_N PF04675.14 RLN87661.1 - 9.4e-39 133.5 0.5 4.8e-38 131.2 0.3 2.2 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 RLN87661.1 - 1.2e-33 116.5 0.0 2e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain BRCT_2 PF16589.5 RLN87661.1 - 2.2e-13 50.4 0.0 3.1e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 RLN87661.1 - 9.8e-13 48.6 0.0 6.1e-12 46.0 0.0 2.4 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_IV PF11411.8 RLN87661.1 - 7e-07 29.3 0.1 1.5e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 DNA ligase IV BRCT PF00533.26 RLN87661.1 - 1.5e-06 28.4 0.0 0.037 14.4 0.0 3.8 3 2 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain RNA_ligase PF09414.10 RLN87661.1 - 2.2e-06 28.1 0.0 4.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 RNA ligase LIG3_BRCT PF16759.5 RLN87661.1 - 0.0003 21.0 0.0 0.13 12.5 0.0 2.5 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 RLN87661.1 - 0.0011 18.9 0.1 0.38 10.7 0.1 2.5 2 0 0 2 2 2 2 twin BRCT domain SR1P PF13790.6 RLN87662.1 - 0.071 13.2 0.2 0.13 12.4 0.2 1.4 1 0 0 1 1 1 0 SR1 protein UNC-50 PF05216.13 RLN87663.1 - 3.2e-48 164.2 19.2 1.5e-38 132.6 10.9 2.5 2 1 0 2 2 2 2 UNC-50 family PAE PF03283.13 RLN87664.1 - 8.1e-12 44.9 0.0 1.7e-11 43.9 0.0 1.6 1 1 0 1 1 1 1 Pectinacetylesterase DUF2235 PF09994.9 RLN87664.1 - 0.021 14.2 0.0 0.052 12.9 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_3 PF07859.13 RLN87664.1 - 0.32 10.8 1.2 0.9 9.4 0.0 2.4 4 1 1 5 5 5 0 alpha/beta hydrolase fold POB3_N PF17292.2 RLN87665.1 - 3.6e-09 36.9 0.0 3.9e-09 36.8 0.0 1.0 1 0 0 1 1 1 1 POB3-like N-terminal PH domain PH_TFIIH PF08567.11 RLN87665.1 - 0.034 14.5 0.0 0.042 14.2 0.0 1.1 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain Pkinase PF00069.25 RLN87666.1 - 4.3e-58 196.7 0.0 6.8e-58 196.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN87666.1 - 3.7e-43 147.7 0.0 5.5e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN87666.1 - 0.00049 19.0 0.0 0.00085 18.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN87666.1 - 0.0011 18.3 0.0 0.007 15.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like DDE_Tnp_1_4 PF13701.6 RLN87666.1 - 0.014 13.7 0.1 0.022 13.0 0.1 1.2 1 0 0 1 1 1 0 Transposase DDE domain group 1 adh_short PF00106.25 RLN87669.1 - 3.1e-43 147.5 0.0 4.3e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN87669.1 - 4.8e-28 98.3 0.0 7.8e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN87669.1 - 3.9e-11 43.2 0.1 1.2e-10 41.6 0.1 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN87669.1 - 0.011 15.2 0.1 0.031 13.7 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RLN87669.1 - 0.016 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Eno-Rase_NADH_b PF12242.8 RLN87669.1 - 0.05 13.4 0.4 0.16 11.7 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.6 RLN87669.1 - 0.081 13.4 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF812 PF05667.11 RLN87670.1 - 0.0021 17.0 1.4 0.0024 16.9 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF896 PF05979.12 RLN87670.1 - 0.64 9.9 3.4 0.32 10.9 1.3 1.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) AhpC-TSA PF00578.21 RLN87671.1 - 7.6e-24 84.0 0.0 9.9e-24 83.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RLN87671.1 - 2.1e-11 43.8 0.0 2.9e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 RLN87671.1 - 2.3e-10 40.1 0.2 4.2e-10 39.3 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 RLN87671.1 - 0.029 14.5 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Ribosomal_L27A PF00828.19 RLN87672.1 - 7.1e-40 136.6 1.5 1.1e-39 136.0 1.5 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A ADK PF00406.22 RLN87674.1 - 1.7e-28 99.6 0.0 3.4e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 RLN87674.1 - 2.1e-16 60.6 0.0 8.1e-16 58.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 RLN87674.1 - 1e-07 32.2 0.6 6.5e-07 29.6 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 RLN87674.1 - 9.9e-06 26.1 0.1 3.6e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RLN87674.1 - 9.1e-05 22.9 0.0 0.00018 21.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 RLN87674.1 - 0.00047 19.9 0.1 0.0017 18.2 0.0 2.0 2 0 0 2 2 2 1 Cytidylate kinase Rad17 PF03215.15 RLN87674.1 - 0.004 17.1 0.0 0.3 11.0 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 RLN87674.1 - 0.0054 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Thymidylate_kin PF02223.17 RLN87674.1 - 0.0065 16.2 1.3 3.1 7.4 0.0 3.6 3 1 0 3 3 3 1 Thymidylate kinase AAA_28 PF13521.6 RLN87674.1 - 0.0087 16.3 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 RLN87674.1 - 0.011 16.2 0.0 0.051 14.1 0.0 2.1 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.12 RLN87674.1 - 0.011 15.6 0.0 0.033 14.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 RLN87674.1 - 0.012 16.0 0.1 0.029 14.8 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 RLN87674.1 - 0.015 15.7 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 RLN87674.1 - 0.024 14.9 0.0 0.073 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 RLN87674.1 - 0.036 14.1 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 RLN87674.1 - 0.039 13.7 0.0 0.094 12.4 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 RLN87674.1 - 0.056 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 NTPase DUF3987 PF13148.6 RLN87674.1 - 0.056 12.4 0.2 5.1 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Hydin_ADK PF17213.3 RLN87674.1 - 0.067 13.5 4.3 0.16 12.2 0.0 2.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain dNK PF01712.19 RLN87674.1 - 0.11 12.4 0.1 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 Deoxynucleoside kinase Agenet PF05641.12 RLN87675.1 - 2.7e-05 24.5 0.0 8.5e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Agenet domain DUF4537 PF15057.6 RLN87675.1 - 0.072 13.1 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) CDC45 PF02724.14 RLN87675.1 - 0.36 9.1 8.4 0.4 8.9 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 RLN87675.1 - 2.3 6.2 14.7 2.8 5.9 14.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi PAP2 PF01569.21 RLN87676.1 - 1.6e-06 28.0 3.6 1.6e-06 28.0 3.6 2.1 1 1 1 2 2 2 1 PAP2 superfamily DUF2754 PF10953.8 RLN87676.1 - 0.0092 16.2 0.1 0.026 14.8 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2754) DUF2070 PF09843.9 RLN87676.1 - 6.8 4.9 7.2 19 3.4 7.2 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) TRAPPC9-Trs120 PF08626.11 RLN87678.1 - 1.5e-34 118.7 0.0 3.7e-21 74.3 0.0 4.0 4 0 0 4 4 4 4 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DEAD PF00270.29 RLN87679.1 - 1.3e-41 142.3 0.0 2.1e-41 141.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 RLN87679.1 - 0.00019 21.5 0.0 0.00044 20.3 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 RLN87679.1 - 0.0031 16.8 0.2 0.0058 16.0 0.2 1.7 1 1 0 1 1 1 1 SecA DEAD-like domain DUF3654 PF12376.8 RLN87679.1 - 0.93 9.7 6.2 1 9.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3654) DUF4549 PF15082.6 RLN87679.1 - 2.7 7.8 7.3 0.091 12.5 0.4 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4549) Complex1_LYR PF05347.15 RLN87680.1 - 5.8e-14 51.9 0.3 8.1e-14 51.4 0.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) zf-ribbon_3 PF13248.6 RLN87680.1 - 2.1e-05 23.8 4.3 2.1e-05 23.8 4.3 1.9 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.7 RLN87680.1 - 0.00016 21.6 0.7 0.00016 21.6 0.7 1.6 2 0 0 2 2 2 1 Double zinc ribbon Complex1_LYR_2 PF13233.6 RLN87680.1 - 0.00026 21.7 0.3 0.00034 21.3 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 RLN87680.1 - 0.00034 21.2 0.7 0.002 18.7 0.7 1.9 1 1 0 1 1 1 1 Complex1_LYR-like zinc_ribbon_2 PF13240.6 RLN87680.1 - 0.00082 19.0 5.5 0.00082 19.0 5.5 1.6 2 0 0 2 2 2 1 zinc-ribbon domain HypA PF01155.19 RLN87680.1 - 0.0024 17.9 0.2 0.0038 17.2 0.2 1.5 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 RLN87680.1 - 0.011 16.5 0.4 0.011 16.5 0.4 1.6 2 0 0 2 2 2 0 zinc-ribbon family NOB1_Zn_bind PF08772.11 RLN87680.1 - 0.023 14.9 3.9 0.036 14.2 2.9 1.8 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Nudix_N_2 PF14803.6 RLN87680.1 - 0.21 11.5 3.0 1.7 8.6 0.4 2.6 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_4 PF13717.6 RLN87680.1 - 0.36 10.8 5.2 0.69 9.9 0.5 2.5 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 RLN87680.1 - 0.67 9.5 3.2 3 7.4 2.8 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding zf-NADH-PPase PF09297.11 RLN87680.1 - 1.1 9.0 10.0 1.1 9.0 0.6 3.0 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain UPF0547 PF10571.9 RLN87680.1 - 2.8 8.1 8.9 3.1 8.0 5.3 2.4 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 Peptidase_M54 PF07998.11 RLN87682.1 - 2.5e-07 30.9 0.0 7.7e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M54 Reprolysin_4 PF13583.6 RLN87682.1 - 0.07 12.8 0.2 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 RLN87682.1 - 0.12 12.9 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like ANAPC4 PF12896.7 RLN87682.1 - 0.17 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Peptidase_M66 PF10462.9 RLN87682.1 - 0.2 10.6 0.1 0.33 9.9 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M57 PF12388.8 RLN87682.1 - 0.4 10.2 1.6 0.83 9.2 1.2 1.7 1 1 1 2 2 2 0 Dual-action HEIGH metallo-peptidase Peptidase_S24 PF00717.23 RLN87683.1 - 2e-06 27.7 0.0 3.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 RLN87683.1 - 0.00045 20.0 0.0 0.0028 17.5 0.0 2.1 2 0 0 2 2 2 1 Signal peptidase, peptidase S26 UL41A PF17591.2 RLN87683.1 - 0.054 13.6 0.7 0.23 11.6 0.0 2.4 2 0 0 2 2 2 0 Herpesvirus UL41A PGK PF00162.19 RLN87683.1 - 0.15 11.0 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Phosphoglycerate kinase TMEM173 PF15009.6 RLN87683.1 - 0.71 9.0 2.7 1.2 8.2 0.1 2.3 2 0 0 2 2 2 0 Transmembrane protein 173 Pkinase PF00069.25 RLN87684.1 - 1.4e-61 208.1 0.0 2.2e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN87684.1 - 1.3e-44 152.4 0.0 2e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN87684.1 - 6.7e-06 25.6 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RLN87684.1 - 2.4e-05 23.3 0.0 4.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN87684.1 - 0.039 13.9 0.1 0.59 10.0 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN87684.1 - 0.061 12.7 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GerD PF17898.1 RLN87684.1 - 0.061 13.3 0.5 0.15 12.0 0.1 1.9 2 0 0 2 2 2 0 Spore germination GerD central core domain PAP2 PF01569.21 RLN87685.1 - 2.7e-09 36.9 0.4 2.7e-09 36.9 0.4 1.9 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 RLN87685.1 - 0.16 12.1 0.1 0.81 9.8 0.0 2.0 2 0 0 2 2 2 0 Divergent PAP2 family CLP_protease PF00574.23 RLN87686.1 - 5.8e-76 254.4 0.1 1.1e-46 159.0 0.0 2.2 2 0 0 2 2 2 2 Clp protease zf-HIT PF04438.16 RLN87686.1 - 8.2e-08 32.0 15.1 1.2e-07 31.4 15.1 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 RLN87686.1 - 0.23 11.6 16.8 0.4 10.8 16.8 1.3 1 0 0 1 1 1 0 MYND finger PMI_typeI PF01238.21 RLN87687.1 - 2.9e-80 270.2 0.0 1.1e-48 166.3 0.0 2.0 1 1 0 2 2 2 2 Phosphomannose isomerase type I ELMO_CED12 PF04727.13 RLN87688.1 - 1e-24 87.6 0.0 1.9e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family MAT1 PF06391.13 RLN87688.1 - 0.023 14.5 7.7 0.087 12.6 1.7 2.8 3 0 0 3 3 3 0 CDK-activating kinase assembly factor MAT1 Peptidase_S24 PF00717.23 RLN87689.1 - 2.8e-07 30.4 0.0 3.5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Arm PF00514.23 RLN87690.1 - 1.2e-22 79.1 22.2 4e-06 26.7 0.1 9.3 9 0 0 9 9 9 5 Armadillo/beta-catenin-like repeat Robl_LC7 PF03259.17 RLN87690.1 - 5.5e-20 70.9 0.0 1.6e-19 69.4 0.0 1.9 1 0 0 1 1 1 1 Roadblock/LC7 domain HEAT_EZ PF13513.6 RLN87690.1 - 4.3e-08 33.5 6.6 0.00063 20.2 0.1 4.5 3 1 1 4 4 4 3 HEAT-like repeat IQ PF00612.27 RLN87690.1 - 0.00062 19.3 0.1 0.002 17.8 0.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif NopRA1 PF16201.5 RLN87690.1 - 0.0047 16.5 0.0 13 5.3 0.0 4.0 3 1 1 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 HEAT_2 PF13646.6 RLN87690.1 - 0.006 17.0 8.7 0.47 10.9 0.1 4.1 3 1 1 4 4 4 2 HEAT repeats LAMTOR5 PF16672.5 RLN87690.1 - 0.0076 16.1 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 HEAT PF02985.22 RLN87690.1 - 0.03 14.6 2.8 1.5 9.3 0.0 4.4 5 0 0 5 5 5 0 HEAT repeat SurA_N_3 PF13624.6 RLN87690.1 - 0.036 13.9 0.9 0.094 12.5 0.9 1.6 1 0 0 1 1 1 0 SurA N-terminal domain UCH PF00443.29 RLN87691.1 - 2.8e-57 194.2 0.0 4.2e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN87691.1 - 6.5e-24 85.1 0.1 5.7e-23 82.0 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ank_4 PF13637.6 RLN87692.1 - 8.5e-06 26.2 0.2 0.0014 19.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN87692.1 - 0.0019 18.8 0.0 0.033 14.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN87692.1 - 0.079 13.6 0.1 58 4.8 0.0 3.5 4 0 0 4 4 4 0 Ankyrin repeat Bestrophin PF01062.21 RLN87693.1 - 0.00058 19.3 0.1 0.00074 19.0 0.1 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Smg8_Smg9 PF10220.9 RLN87694.1 - 0.012 14.0 1.1 0.013 13.8 1.1 1.0 1 0 0 1 1 1 0 Smg8_Smg9 TPH PF13868.6 RLN87699.1 - 3.3e-18 65.3 75.3 3.6e-18 65.2 75.3 1.0 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain REJ PF02010.15 RLN87700.1 - 1.6e-64 218.4 17.4 4.7e-62 210.3 6.2 2.8 3 0 0 3 3 3 2 REJ domain GPS PF01825.21 RLN87700.1 - 9.3e-10 38.9 3.3 9.3e-10 38.9 3.3 2.3 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif DUF4084 PF13321.6 RLN87700.1 - 0.0056 16.3 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4084) Cadherin_3 PF16184.5 RLN87700.1 - 0.15 12.0 2.5 0.5 10.4 0.4 2.8 3 0 0 3 3 3 0 Cadherin-like Streptin-Immun PF11083.8 RLN87700.1 - 0.45 11.0 3.2 3.8 8.0 2.9 2.4 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein EGF_2 PF07974.13 RLN87700.1 - 1.5 9.3 13.8 4.8 7.6 13.8 2.0 1 0 0 1 1 1 0 EGF-like domain Dickkopf_N PF04706.12 RLN87701.1 - 3.9 8.0 7.8 1.2 9.7 0.5 2.4 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region WD40 PF00400.32 RLN87702.1 - 2.8e-35 119.7 10.4 1.1e-08 35.6 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Prp19 PF08606.11 RLN87702.1 - 2.4e-30 104.3 0.8 5.6e-30 103.1 0.8 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 RLN87702.1 - 3.5e-11 43.3 0.1 0.0034 17.6 0.0 5.8 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain zf-Nse PF11789.8 RLN87702.1 - 3e-06 27.0 0.1 5e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Ge1_WD40 PF16529.5 RLN87702.1 - 0.00073 18.6 0.5 0.19 10.7 0.0 3.4 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 RLN87702.1 - 0.002 18.1 0.0 11 5.8 0.0 3.3 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A zf-NOSIP PF15906.5 RLN87702.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 RLN87702.1 - 0.17 12.1 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 U-box domain Hist_deacetyl PF00850.19 RLN87703.1 - 1.6e-20 73.9 0.0 2.4e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain GMC_oxred_N PF00732.19 RLN87704.1 - 1.9e-94 316.4 0.0 2.3e-94 316.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 RLN87704.1 - 3.1e-09 37.5 0.0 6.2e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 RLN87704.1 - 4.6e-07 29.3 0.0 0.026 13.6 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 RLN87704.1 - 1.4e-05 24.3 0.1 2.2e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 RLN87704.1 - 8.5e-05 22.3 1.9 0.00035 20.3 1.9 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RLN87704.1 - 0.00014 21.2 0.0 0.0094 15.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RLN87704.1 - 0.0009 19.4 0.1 0.0039 17.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 RLN87704.1 - 0.0037 16.5 0.0 0.0087 15.3 0.0 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 RLN87704.1 - 0.07 13.7 0.1 4.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 RLN87704.1 - 0.11 12.5 0.0 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 RLN87704.1 - 0.14 11.4 0.7 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Complex1_LYR PF05347.15 RLN87705.1 - 3.3e-09 36.6 0.6 7.1e-09 35.6 0.1 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 RLN87705.1 - 0.02 15.6 1.3 0.06 14.1 1.3 1.9 1 1 0 1 1 1 0 Complex1_LYR-like CCT PF06203.14 RLN87706.1 - 1.1e-17 63.8 8.8 1.9e-17 63.1 8.8 1.3 1 0 0 1 1 1 1 CCT motif zf-CCCH PF00642.24 RLN87707.1 - 7.9e-09 35.2 19.5 2.7e-06 27.1 1.3 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 RLN87707.1 - 1.6e-05 25.2 10.6 0.017 15.6 2.5 2.6 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 RLN87707.1 - 0.00015 21.5 18.1 0.0017 18.1 2.0 2.9 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 RLN87707.1 - 0.00043 20.3 18.9 0.0036 17.3 1.1 3.2 3 1 0 3 3 3 2 Zinc finger domain Torus PF16131.5 RLN87707.1 - 0.0015 19.2 6.1 1.2 9.9 0.3 3.2 2 1 1 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 RLN87707.1 - 0.021 15.0 4.8 0.75 10.0 0.3 2.7 3 0 0 3 3 3 0 Zinc-finger containing family adh_short PF00106.25 RLN87708.1 - 3.6e-41 140.8 2.0 4.1e-20 72.1 0.1 2.7 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN87708.1 - 8.7e-24 84.4 5.5 3.6e-11 43.1 0.1 2.2 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN87708.1 - 8.3e-06 25.8 2.5 0.00018 21.5 0.7 2.2 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 RLN87708.1 - 0.0067 15.9 0.1 0.42 10.0 0.1 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 RLN87708.1 - 0.024 14.5 1.0 0.042 13.7 1.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding ApbA PF02558.16 RLN87708.1 - 0.039 13.6 0.1 0.06 13.0 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 RLN87708.1 - 0.052 13.4 1.5 0.077 12.9 1.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 RLN87708.1 - 0.095 12.1 0.3 0.14 11.6 0.3 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain VPR PF00522.18 RLN87709.1 - 0.063 13.3 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 VPR/VPX protein FYVE PF01363.21 RLN87711.1 - 3.7e-15 55.8 15.5 3.7e-15 55.8 15.5 2.4 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 RLN87711.1 - 0.12 12.6 16.5 0.031 14.5 10.7 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger DHquinase_II PF01220.19 RLN87712.1 - 1.1e-05 25.1 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Dehydroquinase class II zf-C2H2_4 PF13894.6 RLN87712.1 - 0.034 15.0 1.7 0.081 13.8 1.7 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Sec3_C PF09763.9 RLN87714.1 - 2.3e-13 49.4 17.4 2.2e-05 23.1 0.7 4.3 3 1 1 4 4 4 3 Exocyst complex component Sec3 DUF4509 PF14970.6 RLN87714.1 - 0.0071 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4509) TraS PF10624.9 RLN87715.1 - 0.095 12.6 0.1 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS PEX11 PF05648.14 RLN87717.1 - 9.7e-29 100.4 0.6 1.1e-28 100.2 0.6 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) COesterase PF00135.28 RLN87719.1 - 1.6e-52 179.1 1.0 1.4e-51 176.0 1.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RLN87719.1 - 0.019 14.8 0.5 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Methyltransf_25 PF13649.6 RLN87720.1 - 1.1e-06 29.2 0.2 1.1e-06 29.2 0.2 2.2 3 0 0 3 3 3 1 Methyltransferase domain CMAS PF02353.20 RLN87720.1 - 2.1e-05 24.0 0.3 3.4e-05 23.3 0.1 1.4 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 RLN87720.1 - 7.2e-05 22.7 0.1 0.0012 18.7 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 RLN87720.1 - 0.0014 18.1 0.3 0.0029 17.1 0.0 1.7 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_18 PF12847.7 RLN87720.1 - 0.0034 17.3 0.0 0.0048 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN87720.1 - 0.01 16.4 0.1 0.01 16.4 0.1 2.2 3 0 0 3 3 2 0 Methyltransferase domain MetW PF07021.12 RLN87720.1 - 0.013 15.1 0.1 0.013 15.1 0.1 1.4 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW PCMT PF01135.19 RLN87720.1 - 0.019 14.7 0.3 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 RLN87720.1 - 0.021 14.4 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 RLN87720.1 - 0.034 13.9 1.5 0.036 13.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 RLN87720.1 - 0.04 13.9 0.0 0.088 12.8 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 RLN87720.1 - 0.058 12.8 0.1 0.079 12.3 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 RLN87720.1 - 0.063 12.6 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_20 PF12147.8 RLN87720.1 - 0.099 11.8 0.1 0.19 10.8 0.0 1.4 1 1 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 RLN87720.1 - 0.14 11.7 0.7 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain U3_snoRNA_assoc PF08297.11 RLN87721.1 - 0.13 13.0 0.5 0.13 13.0 0.5 2.8 2 1 1 3 3 3 0 U3 snoRNA associated eIF3_subunit PF08597.10 RLN87721.1 - 0.42 10.5 20.8 0.57 10.0 20.8 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4604 PF15377.6 RLN87721.1 - 3.6 8.0 25.0 4.3 7.7 25.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) RR_TM4-6 PF06459.12 RLN87721.1 - 3.9 7.2 13.6 4.9 6.9 13.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 UreE_N PF02814.15 RLN87722.1 - 0.00094 18.7 0.2 0.077 12.6 0.1 3.1 3 0 0 3 3 3 1 UreE urease accessory protein, N-terminal domain ASH PF15780.5 RLN87722.1 - 0.027 14.7 0.0 0.77 10.0 0.1 3.0 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 RLN87722.1 - 0.071 13.3 0.6 0.21 11.8 0.4 1.9 2 0 0 2 2 2 0 Flagellar-associated PapD-like 6PF2K PF01591.18 RLN87723.1 - 4.2e-65 219.2 0.1 5.7e-65 218.7 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 RLN87723.1 - 1.2e-21 77.3 0.0 2.6e-21 76.2 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 RLN87723.1 - 4.2e-09 36.7 0.2 7.4e-09 35.9 0.2 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 RLN87723.1 - 0.019 14.5 0.0 0.038 13.5 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Lant_dehydr_C PF14028.6 RLN87723.1 - 0.077 12.5 0.3 0.12 11.8 0.3 1.3 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term Shisa PF13908.6 RLN87724.1 - 1.9e-05 25.0 0.2 3.8e-05 24.0 0.2 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Rax2 PF12768.7 RLN87724.1 - 0.00019 21.0 1.0 0.00031 20.3 0.2 1.7 2 1 0 2 2 2 1 Cortical protein marker for cell polarity Amnionless PF14828.6 RLN87724.1 - 0.00032 19.7 0.0 0.00039 19.4 0.0 1.1 1 0 0 1 1 1 1 Amnionless Adeno_E3_CR2 PF02439.15 RLN87724.1 - 0.0004 20.1 2.4 0.00093 18.9 2.4 1.6 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Stevor PF17410.2 RLN87724.1 - 0.00064 19.4 0.1 0.00081 19.0 0.1 1.2 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame EphA2_TM PF14575.6 RLN87724.1 - 0.0015 19.3 0.1 0.0038 18.1 0.1 1.7 2 0 0 2 2 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 RLN87724.1 - 0.011 15.8 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 0 Protocadherin TMEM154 PF15102.6 RLN87724.1 - 0.011 15.6 0.0 0.029 14.3 0.0 1.7 1 1 0 1 1 1 0 TMEM154 protein family DUF4051 PF13260.6 RLN87724.1 - 0.019 14.7 0.7 0.033 13.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) MAP17 PF15807.5 RLN87724.1 - 0.02 15.1 0.0 0.032 14.5 0.0 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Herpes_gE PF02480.16 RLN87724.1 - 0.022 13.5 0.0 0.037 12.8 0.0 1.3 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E Orf78 PF06024.12 RLN87724.1 - 0.024 14.9 0.0 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Orthoreo_P10 PF07204.11 RLN87724.1 - 0.039 13.9 0.5 0.1 12.6 0.5 1.7 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Prominin PF05478.11 RLN87724.1 - 0.05 11.6 0.0 0.074 11.0 0.0 1.2 1 0 0 1 1 1 0 Prominin DAP10 PF07213.11 RLN87724.1 - 0.053 13.5 0.3 0.14 12.2 0.3 1.7 1 0 0 1 1 1 0 DAP10 membrane protein SKG6 PF08693.10 RLN87724.1 - 0.064 12.7 4.3 0.13 11.7 4.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Glycophorin_A PF01102.18 RLN87724.1 - 0.067 13.4 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A DUF4330 PF14221.6 RLN87724.1 - 0.1 12.8 0.2 0.15 12.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) Podoplanin PF05808.11 RLN87724.1 - 0.11 12.6 4.0 0.095 12.8 2.9 1.7 1 1 0 1 1 1 0 Podoplanin NICE-3 PF07406.11 RLN87724.1 - 0.13 12.2 0.7 0.22 11.5 0.7 1.3 1 0 0 1 1 1 0 NICE-3 protein RIFIN PF02009.16 RLN87724.1 - 0.18 11.6 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Rifin Syndecan PF01034.20 RLN87724.1 - 0.26 11.2 2.9 0.54 10.2 2.9 1.5 1 0 0 1 1 1 0 Syndecan domain UPF0154 PF03672.13 RLN87724.1 - 0.68 10.0 2.3 3.8 7.6 2.3 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0154) MtrF PF09472.10 RLN87724.1 - 3.7 7.0 6.6 7.4 6.1 6.6 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) NCU-G1 PF15065.6 RLN87724.1 - 3.8 6.4 6.4 4.7 6.1 4.5 1.8 1 1 1 2 2 2 0 Lysosomal transcription factor, NCU-G1 GTP_EFTU PF00009.27 RLN87725.1 - 2.1e-28 99.2 0.0 3.4e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 RLN87725.1 - 3.8e-07 30.4 0.3 1.2e-06 28.8 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RLN87725.1 - 7.3e-07 29.3 0.0 1.4e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RLN87725.1 - 6e-05 23.0 0.3 0.00075 19.4 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 RLN87725.1 - 0.00074 19.0 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ephrin_rec_like PF07699.13 RLN87726.1 - 0.0028 17.4 3.4 0.0028 17.4 3.4 16.5 10 8 10 20 20 20 4 Putative ephrin-receptor like TPR_1 PF00515.28 RLN87727.1 - 1e-31 107.4 3.0 4.7e-06 26.2 0.5 6.1 5 2 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 RLN87727.1 - 1.2e-22 78.1 3.9 0.00015 21.6 0.3 6.0 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 RLN87727.1 - 2.1e-17 62.5 0.5 2.4e-07 30.3 0.1 5.1 5 1 1 6 6 6 2 TPR repeat TPR_8 PF13181.6 RLN87727.1 - 2.2e-17 61.7 4.6 9.5e-05 22.3 0.5 5.8 5 1 0 5 5 5 3 Tetratricopeptide repeat STI1 PF17830.1 RLN87727.1 - 4.1e-16 58.7 0.8 1.7e-15 56.7 0.6 2.1 2 0 0 2 2 2 1 STI1 domain TPR_12 PF13424.6 RLN87727.1 - 1.3e-14 54.2 0.3 2.3e-05 24.6 0.1 3.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 RLN87727.1 - 4.2e-10 39.3 0.7 0.0074 16.6 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN87727.1 - 3.7e-09 36.0 0.1 0.31 11.2 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN87727.1 - 2.6e-08 34.4 0.4 0.00012 22.7 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN87727.1 - 3.1e-07 30.7 0.1 6.8 7.8 0.0 5.5 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN87727.1 - 2e-05 25.0 1.0 0.15 12.6 0.0 4.5 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN87727.1 - 2.4e-05 24.1 0.4 4.6 7.2 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN87727.1 - 0.00019 21.8 2.7 4.4 8.2 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN87727.1 - 0.024 14.7 0.6 0.77 9.9 0.4 2.9 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat RPN7 PF10602.9 RLN87727.1 - 0.032 14.0 0.4 0.032 14.0 0.4 2.3 1 1 1 2 2 2 0 26S proteasome subunit RPN7 DUF3856 PF12968.7 RLN87727.1 - 0.039 14.0 2.5 3.4 7.7 0.3 2.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) DUF357 PF04010.13 RLN87727.1 - 0.05 13.7 0.7 0.92 9.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF357) TUDOR_5 PF18359.1 RLN87728.1 - 0.013 15.1 0.2 0.024 14.3 0.2 1.4 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 DUF2431 PF10354.9 RLN87731.1 - 5e-43 147.3 0.0 9.3e-43 146.4 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) zf-C2H2_2 PF12756.7 RLN87731.1 - 0.0039 17.5 1.9 0.0074 16.6 1.9 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 RLN87731.1 - 0.012 15.9 0.3 0.025 14.9 0.3 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RLN87731.1 - 0.19 12.2 0.7 0.4 11.2 0.7 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type PLAC8 PF04749.17 RLN87733.1 - 2.4e-17 63.8 12.2 7e-17 62.3 12.2 1.7 1 1 0 1 1 1 1 PLAC8 family CclA_1 PF16942.5 RLN87733.1 - 0.078 13.2 1.1 0.13 12.5 1.1 1.4 1 0 0 1 1 1 0 Putative cyclic bacteriocin Peptidase_S66 PF02016.15 RLN87734.1 - 4.1e-34 117.3 0.0 1.3e-33 115.7 0.0 1.8 1 1 0 1 1 1 1 LD-carboxypeptidase N-terminal domain Peptidase_S66C PF17676.1 RLN87734.1 - 3.3e-24 85.8 0.0 5.3e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase C-terminal domain NBD_C PF17042.5 RLN87734.1 - 0.0014 19.2 0.1 0.0022 18.5 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-binding C-terminal domain p450 PF00067.22 RLN87736.1 - 3.6e-72 243.6 0.0 4.5e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ATP19 PF11022.8 RLN87736.1 - 0.055 13.9 0.1 0.15 12.5 0.1 1.7 1 0 0 1 1 1 0 ATP synthase subunit K zf-C3HC4_2 PF13923.6 RLN87737.1 - 6e-06 26.0 2.6 6e-06 26.0 2.6 4.2 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN87737.1 - 0.00023 21.1 3.9 0.00023 21.1 3.9 2.8 2 2 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RLN87737.1 - 0.00038 20.3 4.1 0.00038 20.3 4.1 4.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN87737.1 - 0.00069 19.9 7.8 0.00069 19.9 7.8 4.2 2 2 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 RLN87737.1 - 0.0007 19.5 6.5 0.0007 19.5 6.5 4.2 3 2 0 3 3 3 2 zinc-RING finger domain IBR PF01485.21 RLN87737.1 - 0.0025 18.0 7.8 0.0025 18.0 7.8 3.6 3 1 0 3 3 3 1 IBR domain, a half RING-finger domain Viral_Beta_CD PF04530.12 RLN87737.1 - 3.7 7.9 6.1 4.8 7.5 1.2 2.3 2 0 0 2 2 2 0 Viral Beta C/D like family CHCH PF06747.13 RLN87738.1 - 0.00015 21.8 1.2 0.00021 21.3 1.2 1.2 1 0 0 1 1 1 1 CHCH domain DUF1962 PF09227.10 RLN87738.1 - 0.047 14.1 0.1 0.088 13.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1962) FliT PF05400.13 RLN87739.1 - 0.079 13.8 0.3 0.14 13.0 0.3 1.5 1 0 0 1 1 1 0 Flagellar protein FliT Lung_7-TM_R PF06814.13 RLN87740.1 - 3e-43 148.2 11.1 3.8e-43 147.8 11.1 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 RLN87740.1 - 0.035 13.5 12.0 0.062 12.7 12.0 1.3 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain Astro_capsid_p PF12226.8 RLN87740.1 - 1 8.4 7.3 3.3 6.8 5.1 2.2 2 1 0 2 2 2 0 Turkey astrovirus capsid protein GILT PF03227.16 RLN87741.1 - 0.01 16.1 0.2 0.025 14.8 0.1 1.7 2 0 0 2 2 2 0 Gamma interferon inducible lysosomal thiol reductase (GILT) Lung_7-TM_R PF06814.13 RLN87742.1 - 4e-13 49.3 1.2 6.6e-09 35.4 0.0 2.0 2 0 0 2 2 2 2 Lung seven transmembrane receptor DUF2681 PF10883.8 RLN87745.1 - 0.12 12.8 2.2 0.18 12.2 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) CRAL_TRIO PF00650.20 RLN87746.1 - 6.8e-10 38.9 0.0 1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 RLN87746.1 - 0.00025 21.2 0.0 0.00044 20.4 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SDA1 PF05285.12 RLN87746.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 SDA1 Ribosomal_S10 PF00338.22 RLN87747.1 - 0.11 12.7 0.1 4 7.7 0.0 2.8 3 0 0 3 3 3 0 Ribosomal protein S10p/S20e Spc7 PF08317.11 RLN87747.1 - 0.69 8.7 7.9 1.1 8.1 7.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein adh_short PF00106.25 RLN87749.1 - 1.3e-21 76.9 0.0 1.4e-20 73.6 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN87749.1 - 1.6e-10 41.0 0.0 2.4e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN87749.1 - 0.00087 19.2 0.3 0.0016 18.4 0.1 1.5 2 0 0 2 2 2 1 KR domain PX PF00787.24 RLN87750.1 - 1.9e-07 31.1 0.0 2.9e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 PX domain ACOX PF01756.19 RLN87751.1 - 3e-35 121.4 0.2 5.4e-35 120.6 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 RLN87751.1 - 7.2e-20 71.0 0.2 1.9e-19 69.6 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 RLN87751.1 - 1.4e-19 70.9 0.1 1.6e-18 67.4 0.0 2.6 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 RLN87751.1 - 1.5e-09 38.3 2.0 4.8e-09 36.6 0.6 2.7 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF5584 PF17822.1 RLN87751.1 - 0.039 13.4 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5584) PX PF00787.24 RLN87753.1 - 4.8e-10 39.4 0.4 8.3e-10 38.6 0.4 1.4 1 0 0 1 1 1 1 PX domain WH2 PF02205.20 RLN87753.1 - 5.6e-08 32.4 1.8 1.5e-07 31.0 1.8 1.7 1 0 0 1 1 1 1 WH2 motif Metallophos PF00149.28 RLN87754.1 - 3.2e-30 106.2 0.0 5.4e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase XRN_N PF03159.18 RLN87754.1 - 0.15 11.5 2.8 0.37 10.2 2.8 1.6 1 1 1 2 2 2 0 XRN 5'-3' exonuclease N-terminus Med19 PF10278.9 RLN87754.1 - 0.26 11.2 10.6 0.5 10.3 10.6 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 U1snRNP70_N PF12220.8 RLN87754.1 - 1.6 9.4 9.0 5.3 7.8 9.0 1.9 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal AP3D1 PF06375.11 RLN87754.1 - 4.1 7.6 12.6 1.9 8.7 8.1 2.3 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 NARP1 PF12569.8 RLN87754.1 - 6 5.6 7.6 9.1 5.1 7.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 IQ PF00612.27 RLN87755.1 - 3.2e-06 26.4 91.0 0.94 9.4 0.0 16.9 16 0 0 16 16 16 9 IQ calmodulin-binding motif WW PF00397.26 RLN87755.1 - 6.1e-05 23.0 1.2 0.00062 19.8 0.1 2.6 2 0 0 2 2 2 1 WW domain zf-HIT PF04438.16 RLN87755.1 - 0.0041 17.0 3.0 0.0041 17.0 3.0 5.1 5 1 0 5 5 5 2 HIT zinc finger SAM_2 PF07647.17 RLN87755.1 - 0.11 12.6 0.2 8.3 6.6 0.0 3.6 5 0 0 5 5 5 0 SAM domain (Sterile alpha motif) CaATP_NAI PF12515.8 RLN87755.1 - 0.56 9.9 6.6 0.11 12.1 2.0 2.3 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain zf-B_box PF00643.24 RLN87755.1 - 1.1 9.5 56.3 0.013 15.6 5.7 5.7 5 0 0 5 5 5 0 B-box zinc finger Translin PF01997.16 RLN87756.1 - 7.4e-17 62.0 2.5 1.1e-15 58.2 0.1 2.9 2 1 0 2 2 2 1 Translin family Sep15_SelM PF08806.11 RLN87756.1 - 5.4 7.2 5.2 2.1 8.6 0.4 2.5 2 0 0 2 2 2 0 Sep15/SelM redox domain DUF1899 PF08953.11 RLN87757.1 - 5.5e-24 83.8 0.2 9.5e-24 83.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 RLN87757.1 - 2.9e-18 65.9 2.9 0.00016 22.4 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN87757.1 - 2e-09 37.6 0.1 1.5e-05 25.2 0.1 3.3 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN87757.1 - 0.0012 17.9 0.0 0.35 9.8 0.0 2.6 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 RLN87757.1 - 0.036 13.1 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Pkinase_Tyr PF07714.17 RLN87758.1 - 7.6e-07 28.7 0.0 1.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN87758.1 - 0.00011 21.7 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RYDR_ITPR PF01365.21 RLN87759.1 - 6.5e-10 38.8 0.0 1.3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 RIH domain CI-B14_5a PF07347.12 RLN87761.1 - 0.082 12.8 0.3 0.2 11.6 0.2 1.8 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Arm PF00514.23 RLN87762.1 - 0.0074 16.3 11.1 2.6 8.2 0.3 6.0 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat DUF3652 PF12372.8 RLN87762.1 - 0.033 14.1 0.1 0.16 11.9 0.1 2.2 1 0 0 1 1 1 0 Huntingtin protein region Peptidase_C2 PF00648.21 RLN87763.1 - 6.1e-42 143.7 0.0 1.5e-41 142.4 0.0 1.5 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 RLN87763.1 - 1.5e-14 54.4 0.0 0.0078 16.5 0.0 4.5 4 0 0 4 4 4 4 Calpain large subunit, domain III Cytochrom_B561 PF03188.16 RLN87763.1 - 2.3e-12 47.2 1.9 1.2e-05 25.5 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic cytochrome b561 MIT PF04212.18 RLN87763.1 - 0.21 11.7 9.0 0.17 12.0 6.2 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain bZIP_1 PF00170.21 RLN87763.1 - 0.38 10.9 10.5 0.93 9.6 2.6 2.5 2 0 0 2 2 2 0 bZIP transcription factor TPR_2 PF07719.17 RLN87763.1 - 0.77 10.0 3.2 2.3 8.5 1.6 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat Kelch_4 PF13418.6 RLN87764.1 - 1.3e-09 37.9 0.0 0.045 13.8 0.0 4.1 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN87764.1 - 8.2e-09 35.3 0.0 0.084 12.9 0.0 3.7 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 RLN87764.1 - 1e-07 31.4 2.1 1.4e-05 24.6 1.0 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 RLN87764.1 - 1.7e-06 27.8 5.5 0.00028 20.8 0.7 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 RLN87764.1 - 6.9e-05 23.0 1.0 0.069 13.5 0.1 4.0 4 1 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.6 RLN87764.1 - 0.0041 17.4 0.9 1.7 9.1 0.0 3.4 2 1 1 3 3 3 1 Kelch motif Mito_carr PF00153.27 RLN87765.1 - 7.3e-38 128.4 0.4 2.5e-18 65.8 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein SURF2 PF05477.11 RLN87769.1 - 0.15 11.7 3.7 0.18 11.5 3.7 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) FAM76 PF16046.5 RLN87769.1 - 0.17 11.2 2.6 0.2 11.0 2.6 1.1 1 0 0 1 1 1 0 FAM76 protein DTHCT PF08070.11 RLN87769.1 - 0.58 10.9 7.1 1.1 10.0 7.0 1.4 1 1 0 1 1 1 0 DTHCT (NUC029) region MRI PF15325.6 RLN87769.1 - 1.9 9.6 10.2 0.85 10.7 2.0 1.7 1 1 1 2 2 2 0 Modulator of retrovirus infection Herpes_DNAp_acc PF04929.12 RLN87769.1 - 2.5 7.0 6.9 2.6 6.9 6.9 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RSN1_7TM PF02714.15 RLN87770.1 - 1.8e-07 30.8 9.9 1.8e-07 30.8 9.9 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 RLN87770.1 - 2.5e-07 31.1 0.4 5.1e-07 30.1 0.4 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 RLN87770.1 - 0.093 11.6 9.1 0.0043 15.9 1.7 2.5 2 1 0 2 2 2 0 Calcium-activated chloride channel TraO PF10626.9 RLN87771.1 - 0.061 13.1 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Conjugative transposon protein TraO DUF1298 PF06974.13 RLN87773.1 - 4.4e-28 98.0 1.3 2.3e-27 95.7 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 RLN87773.1 - 9.3e-16 58.4 0.4 2e-15 57.3 0.3 1.5 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Sec23_trunk PF04811.15 RLN87774.1 - 7.7e-45 153.4 0.0 1e-44 152.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 RLN87774.1 - 4.5e-20 71.4 0.2 1.2e-19 70.0 0.2 1.8 1 1 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 RLN87774.1 - 1.1e-19 71.0 0.0 2.1e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 RLN87774.1 - 2e-13 50.1 3.1 4.5e-13 49.0 3.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 RLN87774.1 - 0.024 14.5 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 Gelsolin repeat FATC PF02260.20 RLN87775.1 - 5.8e-15 54.8 1.3 1.8e-14 53.3 1.0 2.0 2 0 0 2 2 2 1 FATC domain NIT PF08376.10 RLN87775.1 - 0.089 13.2 0.7 0.17 12.3 0.7 1.5 1 1 0 1 1 1 0 Nitrate and nitrite sensing DUF455 PF04305.14 RLN87776.1 - 1.9e-80 270.0 0.1 3.4e-80 269.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Glyco_trans_1_4 PF13692.6 RLN87776.1 - 1.5e-15 57.8 0.0 5e-15 56.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 RLN87776.1 - 0.031 14.3 0.0 1.5 8.8 0.0 2.7 3 0 0 3 3 3 0 Glycosyltransferase Family 4 ABC2_membrane PF01061.24 RLN87777.1 - 3.4e-36 124.6 21.6 4.7e-36 124.2 21.6 1.2 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN87777.1 - 3.2e-07 30.2 0.2 1.3e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 RLN87777.1 - 7e-07 28.7 8.8 7e-07 28.7 8.8 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein Pax2_C PF12403.8 RLN87777.1 - 0.069 13.2 0.5 0.51 10.4 0.1 2.1 2 0 0 2 2 2 0 Paired-box protein 2 C terminal DUF4705 PF15788.5 RLN87777.1 - 0.15 12.3 0.3 2.4 8.5 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4705) Clat_adaptor_s PF01217.20 RLN87778.1 - 1.4e-08 34.8 0.1 1.7e-08 34.5 0.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Herpes_ori_bp PF02399.15 RLN87778.1 - 0.11 10.5 0.3 0.13 10.2 0.3 1.1 1 0 0 1 1 1 0 Origin of replication binding protein WD40 PF00400.32 RLN87779.1 - 3.9e-07 30.7 7.9 0.00018 22.2 0.6 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN87779.1 - 2.2e-05 24.6 0.3 5.5 7.4 0.0 4.1 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN87779.1 - 0.0085 14.8 0.1 0.073 11.7 0.0 2.0 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Phage_Gp23 PF10669.9 RLN87779.1 - 0.18 12.1 2.1 0.34 11.2 2.1 1.4 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) NmrA PF05368.13 RLN87780.1 - 5.8e-17 62.0 0.0 7.7e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 RLN87780.1 - 1.6e-13 50.9 0.0 2.6e-13 50.2 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 RLN87780.1 - 0.0078 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 KR domain AhpC-TSA PF00578.21 RLN87780.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family PTH2 PF01981.16 RLN87780.1 - 0.19 12.0 0.0 0.34 11.2 0.0 1.3 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 zf-CGNR PF11706.8 RLN87782.1 - 9.9 6.1 18.4 1.9 8.4 0.5 4.0 3 1 1 4 4 4 0 CGNR zinc finger NmrA PF05368.13 RLN87783.1 - 5.2e-17 62.2 0.0 5.7e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 RLN87783.1 - 7.4e-14 52.0 0.0 1.1e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding AP_endonuc_2 PF01261.24 RLN87783.1 - 0.016 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel KR PF08659.10 RLN87783.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 KR domain Glu_syn_central PF04898.14 RLN87783.1 - 0.1 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Glutamate synthase central domain AhpC-TSA PF00578.21 RLN87783.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family DUF2807 PF10988.8 RLN87784.1 - 3.3e-10 40.0 5.8 3.3e-10 40.0 5.8 2.6 1 1 1 2 2 2 2 Putative auto-transporter adhesin, head GIN domain DUF563 PF04577.14 RLN87785.1 - 1.2e-25 90.9 0.1 5.2e-25 88.8 0.0 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF563) Orthopox_F8 PF05886.11 RLN87786.1 - 4.5 7.5 6.6 13 5.9 5.1 2.3 1 1 1 2 2 2 0 Orthopoxvirus F8 protein DUF2807 PF10988.8 RLN87787.1 - 1e-23 84.1 39.7 1.6e-15 57.4 6.2 5.3 2 2 3 5 5 5 4 Putative auto-transporter adhesin, head GIN domain FYVE PF01363.21 RLN87789.1 - 3e-14 52.9 9.9 5.8e-14 52.0 9.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger Ank_5 PF13857.6 RLN87789.1 - 1.5e-06 28.4 0.3 4.7e-05 23.6 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN87789.1 - 0.0068 17.0 0.3 0.015 15.8 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) EF-hand_6 PF13405.6 RLN87790.1 - 9.4e-05 22.1 0.4 0.00034 20.3 0.2 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 RLN87790.1 - 0.0002 20.6 0.1 0.00046 19.5 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 RLN87790.1 - 0.00055 20.3 0.2 0.0018 18.7 0.0 1.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN87790.1 - 0.009 15.5 0.3 0.016 14.6 0.3 1.5 1 0 0 1 1 1 1 EF hand zf-C2H2_jaz PF12171.8 RLN87791.1 - 4.3e-07 30.0 0.3 9.5e-07 29.0 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RLN87791.1 - 1.5e-06 28.4 0.9 1.5e-06 28.4 0.9 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 RLN87791.1 - 0.0045 16.7 1.4 0.013 15.2 1.4 1.7 1 0 0 1 1 1 1 U1 zinc finger SNRNP27 PF08648.12 RLN87791.1 - 0.006 16.6 1.4 0.006 16.6 1.4 2.2 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins DUF4666 PF15697.5 RLN87791.1 - 0.061 14.0 0.6 0.24 12.1 0.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) HycI PF01750.18 RLN87791.1 - 0.07 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase maturation protease NDUF_B12 PF08122.12 RLN87792.1 - 0.0015 18.5 0.0 0.0034 17.4 0.0 1.6 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Spc7 PF08317.11 RLN87794.1 - 1.6e-05 23.9 15.9 1.6e-05 23.9 15.9 5.3 2 1 3 5 5 5 2 Spc7 kinetochore protein MscS_porin PF12795.7 RLN87794.1 - 3.3e-05 23.6 43.3 3.3e-05 23.6 43.3 6.0 4 2 1 5 5 5 2 Mechanosensitive ion channel porin domain NT-C2 PF10358.9 RLN87794.1 - 0.0014 18.4 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Cnn_1N PF07989.11 RLN87794.1 - 0.059 13.5 0.1 0.059 13.5 0.1 8.6 7 4 1 9 9 9 0 Centrosomin N-terminal motif 1 Lipoxygenase PF00305.19 RLN87795.1 - 1.1e-13 50.6 0.1 3.9e-12 45.4 0.1 2.1 1 1 0 1 1 1 1 Lipoxygenase FYVE PF01363.21 RLN87796.1 - 0.017 15.2 9.8 0.042 14.0 9.8 1.7 1 0 0 1 1 1 0 FYVE zinc finger C1_2 PF03107.16 RLN87796.1 - 0.58 10.5 6.5 1.7 9.0 6.5 1.8 1 1 0 1 1 1 0 C1 domain FYVE_2 PF02318.16 RLN87796.1 - 0.73 10.1 6.7 0.3 11.3 3.2 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger Peptidase_C48 PF02902.19 RLN87797.1 - 8.8e-11 42.1 0.1 2.5e-10 40.6 0.0 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain MULE PF10551.9 RLN87797.1 - 0.00064 20.1 0.4 0.0085 16.5 0.1 2.5 2 0 0 2 2 2 1 MULE transposase domain DDE_3 PF13358.6 RLN87798.1 - 1.6e-11 44.1 0.0 2.4e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease XRN1_D1 PF18332.1 RLN87800.1 - 1.1e-21 77.5 0.0 2.2e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 RLN87800.1 - 4.9e-17 61.8 0.2 1e-16 60.8 0.2 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D2_D3 PF18334.1 RLN87800.1 - 1.4e-07 31.6 0.0 3.3e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain CCDC23 PF15674.5 RLN87801.1 - 0.00024 21.1 16.0 0.00024 21.1 16.0 1.8 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 23 Calc_CGRP_IAPP PF00214.19 RLN87801.1 - 4.3 7.7 7.2 14 6.0 7.2 1.9 1 1 0 1 1 1 0 Calcitonin / CGRP / IAPP family Pkinase_Tyr PF07714.17 RLN87802.1 - 5.1e-40 137.4 0.0 1.1e-39 136.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RLN87802.1 - 1.8e-36 125.9 0.0 3.7e-36 124.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 RLN87802.1 - 4.5e-11 43.2 0.1 1.9e-05 25.2 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RLN87802.1 - 8.8e-11 41.8 0.5 3.7e-05 24.0 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 RLN87802.1 - 3.4e-10 40.2 0.5 8.1e-05 23.1 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN87802.1 - 5.4e-08 33.0 1.1 8.6e-05 22.8 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN87802.1 - 8e-08 32.0 0.3 4.7e-05 23.5 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeat Kinase-like PF14531.6 RLN87802.1 - 0.012 15.0 0.0 0.027 13.8 0.0 1.6 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 RLN87802.1 - 0.016 15.2 2.4 0.087 12.7 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN87802.1 - 0.059 12.7 0.6 0.28 10.5 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family OrfB_Zn_ribbon PF07282.11 RLN87804.1 - 7.1e-15 54.7 1.8 1.4e-14 53.8 1.8 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HTH_OrfB_IS605 PF12323.8 RLN87804.1 - 1.2e-08 34.3 0.6 7.5e-08 31.7 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain GLTP PF08718.11 RLN87804.1 - 0.0014 18.9 1.0 0.058 13.7 0.3 2.4 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) OrfB_IS605 PF01385.19 RLN87804.1 - 0.0028 17.9 3.6 0.023 14.9 3.6 2.3 1 1 0 1 1 1 1 Probable transposase C1_2 PF03107.16 RLN87804.1 - 0.0045 17.3 2.4 0.011 16.0 2.4 1.7 1 0 0 1 1 1 1 C1 domain Glyco_transf_20 PF00982.21 RLN87805.1 - 4e-151 503.9 0.0 2e-98 330.2 0.0 3.0 2 1 0 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 RLN87805.1 - 8.6e-43 146.1 0.0 5.2e-42 143.6 0.0 2.0 1 1 0 1 1 1 1 Trehalose-phosphatase Lipase_GDSL PF00657.22 RLN87805.1 - 0.045 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase HAD PF12710.7 RLN87805.1 - 0.1 13.0 0.1 39 4.6 0.0 3.4 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase HMA PF00403.26 RLN87806.1 - 2.1e-07 31.3 0.1 2.8e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain Rad10 PF03834.14 RLN87807.1 - 9.9e-38 128.7 0.1 1.8e-37 127.8 0.1 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 RLN87807.1 - 4.7e-06 27.1 0.0 9.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 RLN87807.1 - 2.2e-05 24.1 0.0 4.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.7 RLN87807.1 - 7.1e-05 22.8 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif FYVE PF01363.21 RLN87808.1 - 6.3e-06 26.2 9.9 1.4e-05 25.1 9.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN87808.1 - 0.8 9.9 7.0 2 8.7 7.0 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Na_Ca_ex PF01699.24 RLN87809.1 - 0.0015 18.5 5.3 0.0016 18.4 5.3 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Glyco_hydro_18 PF00704.28 RLN87810.1 - 0.00018 21.4 0.0 0.00055 19.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 FYVE PF01363.21 RLN87811.1 - 5e-11 42.6 6.7 5e-11 42.6 6.7 1.6 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 RLN87811.1 - 0.017 15.3 6.3 0.022 15.0 4.6 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger Vps39_2 PF10367.9 RLN87811.1 - 0.11 12.9 1.7 12 6.4 1.7 2.5 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 C1_1 PF00130.22 RLN87811.1 - 1.5 8.8 8.2 0.099 12.5 2.3 2.0 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-B_box PF00643.24 RLN87811.1 - 8.7 6.6 15.1 0.24 11.6 6.1 2.9 3 1 0 3 3 3 0 B-box zinc finger F5_F8_type_C PF00754.25 RLN87812.1 - 0.00018 21.6 0.1 0.00048 20.2 0.0 1.7 2 0 0 2 2 2 1 F5/8 type C domain DUF2322 PF10084.9 RLN87812.1 - 0.1 12.7 0.1 0.5 10.4 0.0 2.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) ASH PF15780.5 RLN87813.1 - 1.7e-11 44.2 0.9 1.3e-06 28.5 0.1 3.7 3 0 0 3 3 3 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 RLN87813.1 - 3.7e-07 30.0 0.1 1.8e-06 27.7 0.0 2.2 3 0 0 3 3 3 1 MSP (Major sperm protein) domain TMEM131_like PF12371.8 RLN87813.1 - 0.0024 18.1 0.2 0.12 12.6 0.0 2.8 3 0 0 3 3 3 1 Transmembrane protein 131-like DUF4250 PF14056.6 RLN87813.1 - 0.0074 16.2 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4250) ABC_tran_CTD PF16326.5 RLN87813.1 - 0.024 14.9 1.0 0.13 12.5 1.0 2.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain Elicitin PF00964.17 RLN87814.1 - 1.1e-16 60.6 1.0 1.1e-16 60.6 1.0 2.5 2 1 0 2 2 2 1 Elicitin SWI-SNF_Ssr4 PF08549.10 RLN87814.1 - 0.42 9.2 10.4 0.52 8.9 10.4 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Plasmodium_Vir PF05795.11 RLN87814.1 - 1.4 8.2 6.2 1.6 8.1 6.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Hid1 PF12722.7 RLN87814.1 - 5 5.1 6.7 5.7 4.9 6.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF966 PF06136.13 RLN87814.1 - 8.8 5.9 11.4 9.9 5.8 11.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Mito_carr PF00153.27 RLN87815.1 - 3.7e-55 183.9 6.5 1.4e-23 82.6 1.0 4.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 RLN87815.1 - 0.05 12.8 0.1 0.11 11.7 0.1 1.7 1 0 0 1 1 1 0 Gammaproteobacterial serine protease RTBV_P46 PF06216.11 RLN87816.1 - 0.34 9.8 3.0 0.64 8.9 3.0 1.4 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein Peptidase_M19 PF01244.21 RLN87816.1 - 0.44 9.7 5.1 0.24 10.6 2.7 1.8 1 1 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) DUF4686 PF15742.5 RLN87816.1 - 1.5 7.8 64.3 0.19 10.8 34.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) GST_N_2 PF13409.6 RLN87817.1 - 4.5e-20 71.7 0.0 1.1e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN87817.1 - 1.9e-12 47.0 0.0 5.8e-12 45.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RLN87817.1 - 1.6e-08 34.6 0.0 2.9e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RLN87817.1 - 1.8e-05 25.1 0.0 0.034 14.5 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RLN87817.1 - 3.6e-05 23.9 0.1 7.2e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 RLN87817.1 - 0.00021 21.0 0.1 0.00039 20.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain She9_MDM33 PF05546.11 RLN87817.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family Raptor_N PF14538.6 RLN87818.1 - 1e-64 216.9 0.0 1.8e-64 216.1 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 RLN87818.1 - 1.4e-11 43.6 4.5 0.0054 16.9 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 RLN87818.1 - 2.5e-07 31.0 0.1 1.4e-05 25.4 0.0 3.4 3 1 1 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 RLN87818.1 - 5e-07 30.1 0.4 0.0012 19.2 0.0 3.8 3 0 0 3 3 3 2 HEAT-like repeat Cnd1 PF12717.7 RLN87818.1 - 8.1e-07 29.2 0.0 0.00051 20.1 0.0 3.0 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 WD40 PF00400.32 RLN87818.1 - 8e-06 26.5 0.0 2.4 9.2 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN87818.1 - 0.005 17.1 0.0 2.4 8.5 0.0 3.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain UNC45-central PF11701.8 RLN87818.1 - 0.045 13.7 0.0 5.4 7.0 0.1 2.6 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central PIP5K PF01504.18 RLN87819.1 - 7.2e-24 84.5 0.0 9.2e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase ICL PF00463.21 RLN87820.1 - 0.0028 16.2 0.0 0.0035 15.9 0.0 1.1 1 0 0 1 1 1 1 Isocitrate lyase family GDP_Man_Dehyd PF16363.5 RLN87821.1 - 4.2e-145 483.3 0.0 5.2e-145 483.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RLN87821.1 - 2.5e-67 226.8 0.0 3.3e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 RLN87821.1 - 3.7e-06 26.2 0.0 6.3e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RLN87821.1 - 0.033 13.3 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PH PF00169.29 RLN87823.1 - 6.8e-26 90.8 0.2 1.6e-16 60.7 0.0 3.1 3 0 0 3 3 3 2 PH domain VPS9 PF02204.18 RLN87823.1 - 2.3e-13 50.3 0.1 3.8e-13 49.6 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PH_8 PF15409.6 RLN87823.1 - 3.8e-08 33.5 0.8 0.0001 22.5 0.1 2.8 2 0 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 RLN87823.1 - 1.5e-07 31.4 0.0 0.027 14.6 0.0 2.5 2 0 0 2 2 2 2 PH domain PDZ PF00595.24 RLN87823.1 - 3.9e-07 30.3 0.0 1.1e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PH_11 PF15413.6 RLN87823.1 - 4.5e-05 23.8 1.7 0.02 15.3 1.1 3.5 2 1 0 2 2 2 1 Pleckstrin homology domain PDZ_6 PF17820.1 RLN87823.1 - 0.00018 21.3 0.1 0.00041 20.1 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Mcp5_PH PF12814.7 RLN87823.1 - 0.065 13.4 0.1 0.31 11.2 0.0 2.2 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology C2 PF00168.30 RLN87824.1 - 9.5e-06 25.9 0.0 1.8e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain GTP_EFTU PF00009.27 RLN87826.1 - 1.9e-19 70.0 0.2 2.3e-19 69.7 0.2 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DnaJ PF00226.31 RLN87827.1 - 4.2e-09 36.4 0.0 7.5e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Phage_GPD PF05954.11 RLN87827.1 - 0.049 12.9 2.1 0.061 12.6 2.1 1.1 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) RIC3 PF15361.6 RLN87827.1 - 0.11 12.9 0.4 11 6.5 0.2 2.2 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 DUF5545 PF17699.1 RLN87827.1 - 0.13 12.1 0.7 0.17 11.7 0.2 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5545) NUDIX PF00293.28 RLN87828.1 - 4.8e-14 52.5 0.2 8.4e-14 51.7 0.2 1.4 1 0 0 1 1 1 1 NUDIX domain Ank_2 PF12796.7 RLN87829.1 - 1.9e-28 98.9 2.9 2.5e-09 37.6 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN87829.1 - 7.8e-26 90.1 8.2 2.3e-07 31.2 0.1 4.4 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN87829.1 - 1e-19 68.5 0.9 0.00063 20.0 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 RLN87829.1 - 6.1e-18 64.7 4.7 9.1e-05 22.7 0.0 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 RLN87829.1 - 1.3e-15 57.1 8.9 0.00018 21.8 0.0 5.4 6 0 0 6 6 6 3 Ankyrin repeat PBP PF01161.20 RLN87832.1 - 3.3e-11 43.6 0.2 4.6e-11 43.2 0.2 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DELLA PF12041.8 RLN87833.1 - 0.0029 17.4 0.1 0.04 13.8 0.0 2.4 2 0 0 2 2 2 1 Transcriptional regulator DELLA protein N terminal Cep57_MT_bd PF06657.13 RLN87833.1 - 0.36 11.3 0.2 0.36 11.3 0.2 4.0 5 0 0 5 5 5 0 Centrosome microtubule-binding domain of Cep57 DnaJ PF00226.31 RLN87834.1 - 1.4e-18 66.7 0.1 3.6e-18 65.4 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain FixQ PF05545.11 RLN87834.1 - 4.3 7.4 5.8 0.86 9.6 0.5 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DDE_Tnp_4 PF13359.6 RLN87836.1 - 2.5e-22 79.2 0.0 1e-21 77.3 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 RLN87836.1 - 9.7e-05 22.1 0.5 0.00067 19.4 0.5 2.2 1 1 0 1 1 1 1 Transposase DDE domain DUF2423 PF10338.9 RLN87837.1 - 1.2e-10 41.4 1.8 1.2e-10 41.4 1.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) ADH_zinc_N PF00107.26 RLN87837.1 - 0.14 12.2 1.0 0.44 10.5 0.4 1.8 1 1 1 2 2 2 0 Zinc-binding dehydrogenase Laps PF10169.9 RLN87837.1 - 1.3 9.6 11.7 6.8 7.3 11.7 2.0 1 1 0 1 1 1 0 Learning-associated protein CEP19 PF14933.6 RLN87838.1 - 1.3e-20 74.4 0.1 4.3e-19 69.4 0.1 2.2 1 1 0 1 1 1 1 CEP19-like protein MoaE PF02391.17 RLN87839.1 - 1.2e-40 138.3 0.1 1.5e-40 138.0 0.1 1.1 1 0 0 1 1 1 1 MoaE protein DUF3460 PF11943.8 RLN87839.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) CHORD PF04968.12 RLN87840.1 - 0.00012 22.7 3.7 0.00025 21.7 3.7 1.5 1 0 0 1 1 1 1 CHORD KIAA1430 PF13879.6 RLN87840.1 - 0.017 15.9 4.3 0.017 15.9 4.3 3.5 1 1 2 3 3 3 0 KIAA1430 homologue BTK PF00779.19 RLN87840.1 - 0.026 14.3 1.0 0.068 13.0 1.0 1.7 1 0 0 1 1 1 0 BTK motif Rab_bind PF16704.5 RLN87840.1 - 0.067 13.2 11.3 0.12 12.5 1.8 3.4 2 0 0 2 2 2 0 Rab binding domain DUF812 PF05667.11 RLN87840.1 - 0.075 11.9 39.3 0.11 11.4 39.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DASH_Hsk3 PF08227.11 RLN87840.1 - 0.11 12.9 0.7 4.5 7.7 0.0 3.1 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like ATG16 PF08614.11 RLN87840.1 - 0.11 12.7 49.0 4.2 7.5 8.7 3.6 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) HAUS-augmin3 PF14932.6 RLN87840.1 - 3.1 7.3 44.2 0.73 9.4 16.2 3.6 1 1 3 4 4 4 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 RLN87840.1 - 6.9 7.4 30.4 0.78 10.4 4.1 4.8 3 2 2 5 5 5 0 SlyX GYF_2 PF14237.6 RLN87841.1 - 3.8e-23 81.0 0.7 1.3e-12 47.3 0.1 2.7 2 0 0 2 2 2 2 GYF domain 2 RRM_1 PF00076.22 RLN87841.1 - 3.9e-11 42.6 0.0 2.9e-06 27.0 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RLN87841.1 - 0.00043 20.1 0.0 0.00085 19.1 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 RLN87841.1 - 0.0052 16.8 0.1 0.25 11.4 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 RLN87841.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vpu PF00558.19 RLN87841.1 - 1.1 9.1 9.8 4.3 7.2 0.2 2.9 2 0 0 2 2 2 0 Vpu protein Herpes_DNAp_acc PF04929.12 RLN87841.1 - 3.6 6.5 12.8 1.5 7.7 3.5 2.5 3 0 0 3 3 3 0 Herpes DNA replication accessory factor Med19 PF10278.9 RLN87841.1 - 9.3 6.1 12.2 12 5.8 6.6 2.4 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Par3_HAL_N_term PF12053.8 RLN87842.1 - 0.027 14.7 0.1 0.19 11.9 0.1 2.3 1 1 0 1 1 1 0 N-terminal of Par3 and HAL proteins Aminotran_5 PF00266.19 RLN87845.1 - 2.7e-32 112.1 0.0 3.6e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 RLN87845.1 - 2.1e-09 37.2 0.1 3.4e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 RLN87845.1 - 4.3e-06 25.5 0.0 6.2e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 RLN87845.1 - 8.2e-06 25.2 0.0 1.1e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_C107 PF17222.3 RLN87845.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Viral cysteine endopeptidase C107 SGL PF08450.12 RLN87846.1 - 2.3e-37 128.9 0.0 2.9e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 RLN87846.1 - 0.0073 16.4 0.0 0.1 12.7 0.0 2.7 2 1 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.20 RLN87846.1 - 0.028 14.6 0.0 0.19 12.0 0.0 2.2 2 0 0 2 2 2 0 Arylesterase Reg_prop PF07494.11 RLN87846.1 - 0.69 10.3 3.5 49 4.7 0.0 4.8 6 0 0 6 6 6 0 Two component regulator propeller SGL PF08450.12 RLN87847.1 - 2.6e-31 109.1 0.1 3.2e-31 108.8 0.1 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 RLN87847.1 - 0.014 15.5 0.0 0.054 13.6 0.0 1.9 1 0 0 1 1 1 0 Strictosidine synthase Reg_prop PF07494.11 RLN87847.1 - 0.17 12.2 1.4 23 5.6 0.1 4.2 4 0 0 4 4 4 0 Two component regulator propeller Dynamin_N PF00350.23 RLN87848.1 - 1.7e-11 44.5 0.0 8.1e-10 39.0 0.0 2.3 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 RLN87848.1 - 2.8e-07 30.6 0.0 6.2e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 RLN87848.1 - 0.0015 18.8 0.1 1.6 9.0 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 RLN87848.1 - 0.014 15.3 0.5 0.55 10.1 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase FeoB_N PF02421.18 RLN87848.1 - 0.026 14.1 0.0 2.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AIG1 PF04548.16 RLN87848.1 - 0.061 12.7 0.0 2 7.7 0.0 2.3 2 0 0 2 2 2 0 AIG1 family GTP_EFTU PF00009.27 RLN87848.1 - 0.078 12.5 0.0 9 5.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Septin PF00735.18 RLN87848.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Septin G-alpha PF00503.20 RLN87848.1 - 0.18 10.9 0.1 0.76 8.9 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit Ras PF00071.22 RLN87848.1 - 0.2 11.2 0.0 2.8 7.5 0.0 2.1 2 0 0 2 2 2 0 Ras family WD40 PF00400.32 RLN87849.1 - 3.7e-29 100.4 7.9 0.00017 22.3 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN87849.1 - 1.2e-05 25.5 0.0 0.0025 18.1 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RLN87849.1 - 0.0029 17.0 0.0 0.74 9.1 0.0 2.2 2 0 0 2 2 2 2 WD40-like domain ELYS-bb PF16687.5 RLN87849.1 - 0.031 12.9 0.0 0.087 11.4 0.0 1.6 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin Ge1_WD40 PF16529.5 RLN87849.1 - 0.12 11.3 0.0 7.3 5.4 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ccdc124 PF06244.12 RLN87849.1 - 2.1 8.9 6.2 4.1 8.0 6.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 Nop14 PF04147.12 RLN87849.1 - 7 4.7 11.6 12 3.9 11.6 1.3 1 0 0 1 1 1 0 Nop14-like family Spt20 PF12090.8 RLN87850.1 - 1.7 8.2 9.8 2 8.0 9.8 1.0 1 0 0 1 1 1 0 Spt20 family Microtub_bd PF16796.5 RLN87851.1 - 3.4e-15 56.3 0.0 2.8e-14 53.3 0.0 2.4 1 1 0 1 1 1 1 Microtubule binding Kinesin PF00225.23 RLN87851.1 - 3.6e-13 49.2 0.1 2.7e-12 46.3 0.1 2.2 1 1 0 1 1 1 1 Kinesin motor domain TMF_TATA_bd PF12325.8 RLN87851.1 - 0.018 15.2 8.8 0.018 15.2 8.8 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding PKcGMP_CC PF16808.5 RLN87851.1 - 0.096 12.5 12.0 2.2 8.2 0.6 4.5 3 1 1 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Filament PF00038.21 RLN87851.1 - 0.16 11.5 26.4 2.6 7.6 26.0 2.3 1 1 0 1 1 1 0 Intermediate filament protein Glyco_hydro_106 PF17132.4 RLN87851.1 - 0.17 10.1 0.6 0.27 9.5 0.6 1.2 1 0 0 1 1 1 0 alpha-L-rhamnosidase BLOC1_2 PF10046.9 RLN87851.1 - 0.2 12.0 14.5 0.25 11.7 2.3 4.0 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Hex_IIIa PF02455.16 RLN87851.1 - 0.25 10.1 2.5 0.14 10.9 0.4 1.5 2 0 0 2 2 2 0 Hexon-associated protein (IIIa) YabA PF06156.13 RLN87851.1 - 0.28 11.8 17.7 0.7 10.6 3.6 3.8 3 1 1 4 4 4 0 Initiation control protein YabA DUF2407_C PF13373.6 RLN87851.1 - 0.3 11.2 5.9 0.49 10.6 0.8 2.4 2 0 0 2 2 2 0 DUF2407 C-terminal domain Rab5-bind PF09311.11 RLN87851.1 - 0.31 10.4 22.4 0.19 11.1 7.8 2.1 1 1 1 2 2 2 0 Rabaptin-like protein LXG PF04740.12 RLN87851.1 - 0.33 10.6 10.5 0.077 12.7 2.6 3.0 1 1 1 2 2 2 0 LXG domain of WXG superfamily Fib_alpha PF08702.10 RLN87851.1 - 0.34 11.1 12.1 0.94 9.7 6.4 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 RLN87851.1 - 0.39 10.7 4.1 0.66 10.0 0.4 2.4 2 1 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 RLN87851.1 - 0.41 11.1 5.3 0.78 10.3 1.0 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Sec8_exocyst PF04048.14 RLN87851.1 - 0.42 10.5 7.1 1.4 8.8 5.6 2.6 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF812 PF05667.11 RLN87851.1 - 0.67 8.8 29.2 1.3 7.8 6.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) GAS PF13851.6 RLN87851.1 - 0.85 8.9 26.4 0.42 9.9 16.2 2.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 RLN87851.1 - 0.95 10.0 34.1 1.1 9.8 19.2 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 RLN87851.1 - 1.1 9.5 34.9 0.035 14.3 8.7 3.4 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 RLN87851.1 - 1.4 9.0 11.8 0.67 10.0 1.8 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 RLN87851.1 - 1.6 8.8 27.4 0.54 10.3 11.7 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus XhlA PF10779.9 RLN87851.1 - 1.6 9.0 5.8 15 5.9 1.3 2.8 1 1 0 2 2 2 0 Haemolysin XhlA CHDCT2 PF08074.11 RLN87851.1 - 1.6 8.9 6.8 2.5 8.3 5.1 2.3 1 1 0 1 1 1 0 CHDCT2 (NUC038) domain HOOK PF05622.12 RLN87851.1 - 2 6.4 28.2 0.5 8.4 15.4 2.1 1 1 1 2 2 2 0 HOOK protein HXXSHH PF07586.11 RLN87851.1 - 2.4 7.6 12.7 0.077 12.6 5.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1552) MAD PF05557.13 RLN87851.1 - 2.7 6.3 29.0 1.4 7.2 16.5 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF16 PF01519.16 RLN87851.1 - 2.7 8.5 11.3 0.33 11.5 3.0 2.8 1 1 0 2 2 2 0 Protein of unknown function DUF16 Spc7 PF08317.11 RLN87851.1 - 3.2 6.6 28.4 0.26 10.1 19.7 2.1 1 1 2 3 3 3 0 Spc7 kinetochore protein AD PF09793.9 RLN87851.1 - 3.2 7.9 5.4 4.2 7.6 0.5 3.0 2 1 0 2 2 2 0 Anticodon-binding domain HMMR_N PF15905.5 RLN87851.1 - 3.3 7.1 25.3 14 5.1 0.3 2.2 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Exonuc_VII_L PF02601.15 RLN87851.1 - 3.4 7.2 22.5 2.4 7.7 12.1 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit Atg14 PF10186.9 RLN87851.1 - 3.4 6.6 22.6 0.11 11.5 13.4 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 RLN87851.1 - 3.9 7.5 34.2 11 6.1 18.5 3.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CortBP2 PF09727.9 RLN87851.1 - 4 7.3 25.4 0.16 11.9 12.3 2.3 1 1 1 2 2 2 0 Cortactin-binding protein-2 DUF4363 PF14276.6 RLN87851.1 - 5.4 7.2 10.9 1.7 8.8 0.9 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF4363) DUF4407 PF14362.6 RLN87851.1 - 5.6 6.2 21.3 92 2.2 21.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 RLN87851.1 - 7.3 7.1 11.2 2.3 8.7 1.0 4.0 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Het-C PF07217.11 RLN87851.1 - 7.9 4.9 7.1 0.47 8.9 0.9 1.8 1 1 1 2 2 2 0 Heterokaryon incompatibility protein Het-C DUF5082 PF16888.5 RLN87851.1 - 8.4 6.7 17.2 0.23 11.8 4.5 3.0 2 1 1 3 3 2 0 Domain of unknown function (DUF5082) Laminin_II PF06009.12 RLN87851.1 - 9.7 6.2 11.2 6.9 6.7 6.2 2.7 1 1 2 3 3 3 0 Laminin Domain II Lectin_N PF03954.14 RLN87851.1 - 9.9 5.9 12.3 77 3.0 8.3 2.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain GDI PF00996.18 RLN87853.1 - 1.3e-197 656.7 0.0 1.5e-197 656.4 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 RLN87853.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Actin PF00022.19 RLN87854.1 - 1.7e-102 343.1 0.0 1.9e-102 342.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 RLN87854.1 - 0.00063 18.6 0.0 0.045 12.6 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Glucan_synthase PF02364.15 RLN87857.1 - 1.7e-185 618.6 18.0 2e-163 545.6 12.7 3.1 1 1 2 3 3 3 2 1,3-beta-glucan synthase component ERO1 PF04137.15 RLN87858.1 - 6.6e-121 403.8 0.2 8.4e-121 403.5 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) HSP90 PF00183.18 RLN87858.1 - 0.085 11.7 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Hsp90 protein NRN1 PF15056.6 RLN87858.1 - 1.5 9.0 5.2 1.7 8.8 0.4 2.6 2 0 0 2 2 2 0 Neuritin protein family Sas6_CC PF18594.1 RLN87858.1 - 1.6 8.6 3.6 2 8.3 2.1 1.9 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain GATase PF00117.28 RLN87859.1 - 4.6e-16 59.2 0.0 6.8e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 RLN87859.1 - 1.6e-05 24.8 0.0 3.5e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Peptidase C26 Aldedh PF00171.22 RLN87860.1 - 1.9e-88 297.0 0.2 1.7e-60 204.9 0.0 3.0 1 1 2 3 3 3 3 Aldehyde dehydrogenase family adh_short_C2 PF13561.6 RLN87861.1 - 2.6e-64 217.0 5.5 3.1e-64 216.8 5.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RLN87861.1 - 7e-47 159.4 3.3 8.8e-47 159.1 3.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RLN87861.1 - 3.4e-11 43.4 5.1 5.8e-11 42.6 4.9 1.6 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 RLN87861.1 - 0.00074 19.5 3.7 0.0019 18.1 2.8 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 RLN87861.1 - 0.0087 16.2 1.8 0.017 15.3 1.8 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 RLN87861.1 - 0.014 14.5 0.1 0.022 13.9 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 RLN87861.1 - 0.07 12.6 0.3 0.11 12.0 0.3 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family YmgD PF16456.5 RLN87861.1 - 0.18 11.9 5.8 0.095 12.8 2.7 2.0 2 0 0 2 2 2 0 YmgD protein tRNA-synt_2b PF00587.25 RLN87862.1 - 4.9e-08 33.1 0.1 6.1e-08 32.8 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) GATase PF00117.28 RLN87863.1 - 1e-11 45.0 0.0 1.6e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 RLN87863.1 - 0.15 11.8 0.1 0.36 10.5 0.0 1.8 2 1 0 2 2 2 0 Peptidase C26 Questin_oxidase PF14027.6 RLN87864.1 - 1.6e-41 143.0 0.0 2.1e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Questin oxidase-like SAPS PF04499.15 RLN87865.1 - 2.1e-07 30.1 0.0 2.1e-07 30.1 0.0 1.5 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein Sds3 PF08598.11 RLN87866.1 - 0.096 12.7 1.0 3.6 7.5 0.4 2.2 2 0 0 2 2 2 0 Sds3-like Sugar_tr PF00083.24 RLN87870.1 - 1.4e-105 353.8 18.8 1.5e-105 353.7 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN87870.1 - 7.9e-26 90.8 27.9 1.3e-19 70.4 5.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RLN87870.1 - 0.0023 16.6 0.5 0.0023 16.6 0.5 3.2 3 0 0 3 3 3 1 MFS/sugar transport protein BT1 PF03092.16 RLN87870.1 - 0.0027 16.0 0.1 0.0027 16.0 0.1 1.8 2 0 0 2 2 2 1 BT1 family Gly-zipper_Omp PF13488.6 RLN87870.1 - 1.2 9.2 4.4 1.6 8.8 0.5 2.6 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.15 RLN87870.1 - 3.4 7.6 6.5 0.95 9.4 0.9 2.5 2 0 0 2 2 2 0 Glycine zipper 2TM domain DUF423 PF04241.15 RLN87870.1 - 8.3 6.7 8.9 6.4 7.1 0.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF423) DUF4472 PF14739.6 RLN87871.1 - 0.022 15.5 6.1 0.031 15.0 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) DUF4072 PF13284.6 RLN87873.1 - 0.068 13.6 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) LRR_4 PF12799.7 RLN87874.1 - 2e-19 69.3 2.1 3e-05 24.3 0.1 3.5 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN87874.1 - 1e-12 47.9 0.1 1.7e-08 34.2 0.0 2.5 1 1 2 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 RLN87874.1 - 2.8e-09 36.6 7.0 0.0023 17.7 0.1 3.5 3 0 0 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 RLN87874.1 - 0.00011 22.2 6.1 4.8 8.1 0.1 5.0 4 2 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 RLN87874.1 - 0.0084 16.1 0.8 0.5 10.5 0.1 3.7 3 0 0 3 3 3 1 Leucine Rich repeat LRR_2 PF07723.13 RLN87874.1 - 0.093 13.4 0.0 7.4 7.4 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich Repeat Tmemb_185A PF10269.9 RLN87876.1 - 0.00029 20.6 4.7 0.00052 19.8 4.7 1.4 1 1 0 1 1 1 1 Transmembrane Fragile-X-F protein ABC2_membrane_3 PF12698.7 RLN87877.1 - 7.1e-65 219.4 49.0 7.8e-41 140.3 21.3 3.2 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 RLN87877.1 - 1.4e-57 194.0 0.0 2.5e-28 99.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN87877.1 - 1.3e-21 77.8 3.5 1.6e-08 34.7 0.0 4.3 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RLN87877.1 - 1.4e-06 28.3 0.0 0.057 13.1 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 RLN87877.1 - 9.4e-06 26.3 0.2 0.0081 16.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 RLN87877.1 - 0.00017 21.6 0.3 0.014 15.3 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 RLN87877.1 - 0.00054 19.6 2.2 0.0075 16.0 0.2 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 RLN87877.1 - 0.0032 16.9 0.1 4.7 6.6 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RLN87877.1 - 0.0053 17.2 0.0 5.2 7.4 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain SbcCD_C PF13558.6 RLN87877.1 - 0.0098 16.1 0.0 7.6 6.8 0.0 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 RLN87877.1 - 0.011 15.5 0.3 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 RLN87877.1 - 0.016 15.3 0.3 2.6 8.1 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 RLN87877.1 - 0.018 15.3 0.1 2.2 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 RLN87877.1 - 0.065 12.9 3.8 3.5 7.2 0.4 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Arf PF00025.21 RLN87877.1 - 0.075 12.5 0.7 8.2 5.8 0.1 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 RLN87877.1 - 0.091 13.0 0.3 8.8 6.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 RLN87877.1 - 0.11 13.0 0.1 33 4.9 0.0 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 RLN87877.1 - 0.16 11.6 1.5 0.57 9.7 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DLIC PF05783.11 RLN87877.1 - 0.19 10.6 0.2 0.41 9.4 0.0 1.5 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_24 PF13479.6 RLN87877.1 - 0.27 11.0 1.0 12 5.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 RLN87877.1 - 0.51 10.1 2.9 18 5.1 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal ABC2_membrane_5 PF13346.6 RLN87877.1 - 0.64 9.5 36.0 0.073 12.6 16.8 2.9 2 0 0 2 2 2 0 ABC-2 family transporter protein ABC2_membrane PF01061.24 RLN87877.1 - 3.2 7.1 54.0 0.91 8.9 19.6 4.3 4 1 0 4 4 4 0 ABC-2 type transporter DUF3584 PF12128.8 RLN87877.1 - 3.7 4.9 3.4 17 2.7 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ABC2_membrane_3 PF12698.7 RLN87878.1 - 1.7e-20 73.4 20.0 1.8e-19 70.1 20.0 2.4 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 RLN87878.1 - 2.2e-06 27.2 21.0 8.6e-05 22.1 20.0 2.3 2 0 0 2 2 2 2 ABC-2 type transporter BPD_transp_1 PF00528.22 RLN87878.1 - 4.2 7.1 16.6 99 2.6 16.4 2.4 1 1 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component OxoGdeHyase_C PF16870.5 RLN87879.1 - 0.2 11.3 4.4 0.4 10.4 4.4 1.4 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase C-terminal DASH_Duo1 PF08651.10 RLN87880.1 - 0.0073 16.1 2.4 0.0081 15.9 2.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Duo1 Med26 PF08711.11 RLN87881.1 - 3.6e-14 52.5 1.6 9e-14 51.2 1.6 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DEK_C PF08766.11 RLN87881.1 - 1.4e-07 31.3 0.4 4e-07 29.8 0.4 1.9 1 0 0 1 1 1 1 DEK C terminal domain DUF2624 PF11116.8 RLN87881.1 - 0.22 12.5 1.2 1.1 10.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) LacI PF00356.21 RLN87881.1 - 0.39 10.6 3.6 0.51 10.2 0.1 2.8 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family Nop53 PF07767.11 RLN87883.1 - 0.0027 17.2 25.9 0.029 13.8 2.8 2.4 2 0 0 2 2 2 2 Nop53 (60S ribosomal biogenesis) HECT PF00632.25 RLN87885.1 - 3.8e-22 79.1 0.0 4.2e-21 75.7 0.0 2.0 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) cNMP_binding PF00027.29 RLN87887.1 - 1.1e-17 63.9 0.5 1.6e-12 47.3 0.1 3.0 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Peptidase_C97 PF05903.14 RLN87887.1 - 1.9e-17 63.5 0.0 3.6e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain AAA_16 PF13191.6 RLN87887.1 - 4.4e-06 27.2 0.0 2.2e-05 24.9 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 RLN87887.1 - 3.2e-05 23.9 0.3 0.0013 18.7 0.0 3.1 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 RLN87887.1 - 0.00054 20.3 0.0 0.0019 18.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 RLN87887.1 - 0.051 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein DUF2075 PF09848.9 RLN87887.1 - 0.082 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF3929 PF13066.6 RLN87888.1 - 0.076 13.1 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) HMG-CoA_red PF00368.18 RLN87889.1 - 6.6e-52 176.7 0.2 1.2e-51 175.9 0.2 1.4 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HTH_57 PF18679.1 RLN87889.1 - 0.19 12.1 0.1 0.45 10.8 0.1 1.6 1 0 0 1 1 1 0 ThcOx helix turn helix domain AAA_6 PF12774.7 RLN87890.1 - 2.3e-106 355.5 1.6 1.2e-76 257.8 0.0 3.4 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 RLN87890.1 - 7.8e-76 254.8 0.0 4.4e-75 252.4 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 RLN87890.1 - 4.7e-69 231.5 0.1 5.5e-64 215.0 0.1 3.2 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_5 PF07728.14 RLN87890.1 - 9.1e-24 84.0 0.0 1.3e-10 41.4 0.0 4.9 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 RLN87890.1 - 3.4e-22 78.9 0.1 1.7e-21 76.6 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RLN87890.1 - 2.2e-20 72.7 0.2 9.1e-20 70.7 0.2 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 RLN87890.1 - 1e-07 32.5 0.0 0.00063 20.2 0.0 3.5 3 1 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 RLN87890.1 - 1.6e-07 31.9 0.1 0.03 14.7 0.0 3.8 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 RLN87890.1 - 6e-06 25.5 0.0 0.0022 17.1 0.0 2.8 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_19 PF13245.6 RLN87890.1 - 1e-05 25.9 0.0 0.0073 16.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 RLN87890.1 - 1.3e-05 25.1 0.0 0.053 13.4 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_30 PF13604.6 RLN87890.1 - 2.8e-05 23.9 0.0 0.059 13.1 0.0 2.5 3 0 0 3 3 2 2 AAA domain Rad17 PF03215.15 RLN87890.1 - 3.7e-05 23.7 0.1 0.038 13.9 0.1 3.2 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_22 PF13401.6 RLN87890.1 - 4.1e-05 23.9 0.0 0.0022 18.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 RLN87890.1 - 4.7e-05 23.9 0.5 0.014 15.9 0.0 3.2 3 0 0 3 3 3 1 ABC transporter AAA_18 PF13238.6 RLN87890.1 - 5.2e-05 23.8 0.0 5.6 7.5 0.0 4.5 4 0 0 4 4 4 0 AAA domain Sigma54_activat PF00158.26 RLN87890.1 - 0.00049 19.8 0.0 0.51 10.0 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_33 PF13671.6 RLN87890.1 - 0.00054 20.1 0.2 0.039 14.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 RLN87890.1 - 0.00076 19.8 0.1 0.54 10.7 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 RLN87890.1 - 0.00097 18.8 0.0 0.24 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 RLN87890.1 - 0.00099 18.9 0.6 3.6 7.3 0.0 3.3 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 RLN87890.1 - 0.0015 18.7 2.4 0.0086 16.3 0.0 3.1 4 0 0 4 4 3 1 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 RLN87890.1 - 0.0017 18.0 0.6 1.9 8.1 0.1 3.1 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_14 PF13173.6 RLN87890.1 - 0.0019 18.2 0.1 0.016 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 RLN87890.1 - 0.0021 17.3 0.1 0.85 8.7 0.0 2.7 3 0 0 3 3 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 RLN87890.1 - 0.0033 17.7 0.0 0.66 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 RLN87890.1 - 0.0039 17.2 0.0 0.64 10.0 0.0 2.8 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 RLN87890.1 - 0.0064 16.4 0.0 0.33 10.9 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase Mg_chelatase PF01078.21 RLN87890.1 - 0.01 15.3 0.0 8 5.8 0.0 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Pox_A32 PF04665.12 RLN87890.1 - 0.015 14.8 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_2 PF07724.14 RLN87890.1 - 0.025 14.7 0.0 9.8 6.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) Septin PF00735.18 RLN87890.1 - 0.032 13.5 0.3 0.47 9.7 0.2 2.4 2 1 0 2 2 1 0 Septin Ras PF00071.22 RLN87890.1 - 0.032 13.8 0.0 0.083 12.5 0.0 1.7 1 0 0 1 1 1 0 Ras family AAA_29 PF13555.6 RLN87890.1 - 0.036 13.8 2.1 1.9 8.3 0.0 3.3 4 0 0 4 4 3 0 P-loop containing region of AAA domain TniB PF05621.11 RLN87890.1 - 0.043 13.2 0.0 0.33 10.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 RLN87890.1 - 0.048 13.4 0.0 0.29 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 RLN87890.1 - 0.053 13.3 0.0 11 5.7 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein KAP_NTPase PF07693.14 RLN87890.1 - 0.071 12.3 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain TrwB_AAD_bind PF10412.9 RLN87890.1 - 0.086 11.7 0.0 0.21 10.5 0.0 1.6 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.22 RLN87890.1 - 0.1 11.7 0.1 2.5 7.2 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain Sigma54_activ_2 PF14532.6 RLN87890.1 - 0.12 12.4 0.0 2.9 8.0 0.0 2.9 3 0 0 3 3 2 0 Sigma-54 interaction domain Guanylate_kin PF00625.21 RLN87890.1 - 0.14 11.8 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Guanylate kinase ATPase PF06745.13 RLN87890.1 - 0.17 11.2 0.0 1 8.6 0.0 2.2 2 0 0 2 2 2 0 KaiC G-alpha PF00503.20 RLN87890.1 - 0.17 11.1 0.0 2.9 6.9 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit MobB PF03205.14 RLN87890.1 - 0.17 11.8 0.0 0.69 9.8 0.0 2.0 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.9 RLN87890.1 - 0.18 11.0 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ank_2 PF12796.7 RLN87891.1 - 6.9e-108 353.4 32.8 4.8e-17 62.3 1.6 9.4 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN87891.1 - 4.2e-89 291.9 11.3 1.3e-09 38.4 0.1 11.1 7 2 2 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN87891.1 - 1.6e-74 244.9 36.6 2.2e-08 34.2 0.1 15.7 2 2 14 16 16 16 16 Ankyrin repeats (many copies) Ank PF00023.30 RLN87891.1 - 6.2e-70 228.8 39.1 3e-05 24.2 0.0 18.1 18 0 0 18 18 18 14 Ankyrin repeat Ank_3 PF13606.6 RLN87891.1 - 1.5e-64 206.3 16.7 0.016 15.7 0.0 18.6 18 0 0 18 18 18 16 Ankyrin repeat Pkinase_Tyr PF07714.17 RLN87891.1 - 4.1e-52 177.0 0.0 1.2e-42 146.1 0.0 3.3 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN87891.1 - 7.4e-51 173.0 0.0 2.3e-40 138.6 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 RLN87891.1 - 0.00012 21.0 0.0 0.00026 19.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase DUF1949 PF09186.11 RLN87891.1 - 0.00027 20.7 0.3 26 4.8 0.0 5.7 5 0 0 5 5 5 0 Domain of unknown function (DUF1949) PfaD_N PF18328.1 RLN87891.1 - 0.017 15.1 0.0 17 5.4 0.0 3.4 2 0 0 2 2 2 0 Fatty acid synthase subunit PfaD N-terminal domain RIO1 PF01163.22 RLN87891.1 - 0.019 14.6 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 RLN87891.1 - 0.026 14.5 0.0 0.087 12.7 0.0 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3645 PF12359.8 RLN87891.1 - 0.064 12.7 0.1 18 4.8 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3645) PK_C PF02887.16 RLN87891.1 - 6.9 6.9 12.2 61 3.9 0.1 5.8 7 1 0 7 7 5 0 Pyruvate kinase, alpha/beta domain 5TM-5TMR_LYT PF07694.12 RLN87892.1 - 0.037 13.6 2.8 0.052 13.0 0.1 2.5 3 1 0 3 3 3 0 5TMR of 5TMR-LYT FAM83 PF07894.12 RLN87892.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 FAM83 A-H DUF4293 PF14126.6 RLN87892.1 - 2.1 8.6 6.1 0.79 10.0 0.6 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) Pkinase_Tyr PF07714.17 RLN87895.1 - 0.029 13.6 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase CCDC-167 PF15188.6 RLN87896.1 - 1.7 9.1 8.7 0.12 12.7 0.8 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF5320 PF17253.2 RLN87897.1 - 0.63 11.1 12.4 0.36 11.9 1.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5320) Tropomyosin_1 PF12718.7 RLN87897.1 - 1 9.5 12.5 0.37 10.9 0.2 3.3 3 1 0 3 3 3 0 Tropomyosin like Tup_N PF08581.10 RLN87897.1 - 1.2 9.5 11.4 32 4.9 0.0 4.4 4 0 0 4 4 4 0 Tup N-terminal CCDC-167 PF15188.6 RLN87897.1 - 2.4 8.5 16.9 0.85 10.0 0.2 3.6 4 0 0 4 4 4 0 Coiled-coil domain-containing protein 167 PRCC PF10253.9 RLN87898.1 - 0.24 12.2 3.2 0.83 10.4 3.2 1.8 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting CCDC-167 PF15188.6 RLN87898.1 - 1.1 9.7 4.0 0.3 11.4 0.5 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 RsfS PF02410.15 RLN87900.1 - 3.6e-15 56.2 0.2 2.1e-14 53.8 0.1 2.0 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation Yop-YscD_cpl PF16697.5 RLN87901.1 - 6.3e-05 23.2 0.0 0.00015 22.0 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 RLN87901.1 - 0.0002 21.6 0.0 0.00037 20.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain Rhodanese PF00581.20 RLN87902.1 - 3.3e-09 37.2 0.0 3.9e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 Rhodanese-like domain MmlI PF09448.10 RLN87903.1 - 0.21 12.1 0.1 0.77 10.2 0.1 2.0 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase DUF2431 PF10354.9 RLN87904.1 - 1.4e-27 97.0 0.0 2.1e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) zf-C2H2_2 PF12756.7 RLN87904.1 - 0.0015 18.8 1.4 0.003 17.9 1.4 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 RLN87904.1 - 0.0082 16.4 0.3 0.015 15.6 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RLN87904.1 - 0.12 12.8 0.7 0.23 11.9 0.7 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DAO PF01266.24 RLN87905.1 - 6.8e-40 137.7 0.0 7.7e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 RLN87905.1 - 0.00077 18.9 0.0 0.0037 16.7 0.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 RLN87905.1 - 0.036 13.2 0.1 0.036 13.2 0.1 1.4 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 RLN87905.1 - 0.071 13.4 2.8 0.17 12.2 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 RLN87905.1 - 0.13 11.3 2.3 2.7 7.0 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A Ammonium_transp PF00909.21 RLN87906.1 - 1e-66 225.3 9.0 1.2e-66 225.0 9.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3341 PF11821.8 RLN87906.1 - 4.5 6.9 6.1 1.8 8.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Ammonium_transp PF00909.21 RLN87907.1 - 2e-115 385.7 35.4 2.5e-115 385.4 35.4 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Cytomega_TRL10 PF06084.11 RLN87907.1 - 0.077 13.0 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Ammonium_transp PF00909.21 RLN87908.1 - 8.6e-113 377.0 28.5 1.1e-112 376.7 28.5 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Proton_antipo_N PF00662.20 RLN87908.1 - 2.5 8.3 10.1 0.52 10.4 1.9 2.9 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus GCFC PF07842.12 RLN87909.1 - 7.3e-65 219.3 4.6 1.1e-64 218.8 4.6 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 RLN87909.1 - 8.1e-07 28.8 1.7 1.8e-06 27.7 1.7 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 RLN87909.1 - 2.5e-05 24.3 0.7 8.7e-05 22.5 0.7 1.9 1 0 0 1 1 1 1 G-patch domain PI3_PI4_kinase PF00454.27 RLN87911.1 - 6.5e-47 160.4 0.0 1.8e-46 159.0 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase NUC194 PF08163.12 RLN87911.1 - 8.9e-45 153.3 0.1 3e-44 151.5 0.1 2.0 1 1 0 1 1 1 1 NUC194 domain FATC PF02260.20 RLN87911.1 - 3.5e-08 33.1 0.4 1.9e-07 30.8 0.1 2.3 2 0 0 2 2 2 1 FATC domain CNOT11 PF10155.9 RLN87911.1 - 0.021 15.0 0.7 0.18 12.0 0.1 2.9 2 1 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 Imm_superinfect PF14373.6 RLN87911.1 - 0.091 12.7 0.1 0.28 11.1 0.1 1.9 1 0 0 1 1 1 0 Superinfection immunity protein CCER1 PF15482.6 RLN87911.1 - 0.094 12.6 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 Sec1 PF00995.23 RLN87912.1 - 1e-104 351.9 0.0 1.2e-104 351.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family CRAL_TRIO PF00650.20 RLN87913.1 - 1e-17 64.3 0.0 1.9e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 RLN87913.1 - 0.039 14.1 0.1 0.069 13.3 0.1 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain ARD PF03079.14 RLN87913.1 - 0.51 10.5 0.0 0.51 10.5 0.0 3.5 2 1 1 4 4 4 0 ARD/ARD' family GOLD_2 PF13897.6 RLN87913.1 - 3.2 8.3 0.0 3.2 8.3 0.0 4.4 2 2 2 4 4 4 0 Golgi-dynamics membrane-trafficking Ank_5 PF13857.6 RLN87914.1 - 1.1e-13 51.1 0.3 6.7e-09 35.9 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN87914.1 - 0.0028 18.2 0.2 0.065 13.8 0.1 3.1 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN87914.1 - 0.0043 17.6 0.1 0.012 16.2 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN87914.1 - 0.0051 17.2 0.7 3.8 8.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat zf-RING_13 PF17977.1 RLN87914.1 - 0.032 14.4 0.1 0.066 13.4 0.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PWWP PF00855.17 RLN87915.1 - 0.0014 19.0 0.2 0.0024 18.2 0.2 1.4 1 0 0 1 1 1 1 PWWP domain SGL PF08450.12 RLN87916.1 - 2.2e-14 53.7 1.0 6.6e-14 52.1 1.0 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region MMR_HSR1_C PF08438.10 RLN87917.1 - 2.9e-35 121.2 0.0 8.4e-35 119.7 0.0 1.8 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 RLN87917.1 - 4.5e-20 71.8 0.0 1.4e-19 70.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN87917.1 - 1.1e-08 34.8 0.1 1.9e-07 30.8 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B TFIIA PF03153.13 RLN87917.1 - 0.05 13.6 0.7 0.085 12.8 0.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TGS PF02824.21 RLN87917.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 TGS domain CTP_transf_like PF01467.26 RLN87920.1 - 1.7e-16 60.7 0.4 3.1e-16 59.8 0.0 1.6 2 0 0 2 2 2 1 Cytidylyltransferase-like FAD_syn PF06574.12 RLN87920.1 - 0.0018 18.2 0.1 0.012 15.5 0.1 2.2 1 1 0 1 1 1 1 FAD synthetase DivIC PF04977.15 RLN87920.1 - 0.0031 17.2 0.3 0.0057 16.4 0.3 1.3 1 0 0 1 1 1 1 Septum formation initiator DUF2919 PF11143.8 RLN87920.1 - 0.015 15.7 0.0 0.026 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2919) Ribosomal_L10 PF00466.20 RLN87921.1 - 4.1e-24 84.6 0.1 8.4e-24 83.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 RLN87921.1 - 3.1e-21 75.1 0.4 7.2e-21 74.0 0.3 1.7 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 RLN87921.1 - 7.2e-10 39.3 6.8 1.6e-09 38.2 6.8 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein TCR PF03638.15 RLN87922.1 - 5.9e-36 122.5 101.1 1.2e-12 47.9 21.0 4.3 4 0 0 4 4 4 4 Tesmin/TSO1-like CXC domain, cysteine-rich domain Hydrolase_like PF13242.6 RLN87923.1 - 2e-15 56.6 0.0 3.4e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 RLN87923.1 - 5.7e-12 45.6 0.0 1.2e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DcuC PF03606.15 RLN87923.1 - 0.098 11.1 0.2 0.14 10.6 0.2 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier GST_N_2 PF13409.6 RLN87926.1 - 2.1e-24 85.6 0.0 7.5e-16 58.2 0.0 2.7 2 1 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN87926.1 - 6.1e-06 26.2 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RLN87926.1 - 3.6e-05 24.1 0.1 0.081 13.3 0.0 3.7 4 0 0 4 4 4 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RLN87926.1 - 0.0041 17.3 0.0 0.0088 16.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF5548 PF17702.1 RLN87926.1 - 0.0062 16.3 0.0 0.96 9.1 0.0 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5548) GST_C_3 PF14497.6 RLN87926.1 - 0.017 15.3 0.0 0.035 14.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain BOP1NT PF08145.12 RLN87927.1 - 7.6e-10 39.1 0.7 7.6e-10 39.1 0.7 2.2 2 1 1 3 3 3 1 BOP1NT (NUC169) domain Cwf_Cwc_15 PF04889.12 RLN87927.1 - 0.0002 21.2 25.7 0.00028 20.7 25.7 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CDC27 PF09507.10 RLN87927.1 - 0.0039 16.6 31.1 0.0047 16.4 31.1 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 BUD22 PF09073.10 RLN87927.1 - 0.0048 16.3 27.0 0.0063 15.9 27.0 1.3 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 RLN87927.1 - 0.22 9.7 30.4 0.26 9.4 30.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 RLN87927.1 - 0.92 8.4 11.4 1.3 7.9 11.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Astro_capsid_p PF12226.8 RLN87927.1 - 2.1 7.4 15.7 2.7 7.1 15.7 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein LAP1C PF05609.12 RLN87927.1 - 4.1 6.4 21.7 5.3 6.0 21.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PH PF00169.29 RLN87928.1 - 0.0053 17.2 0.0 0.013 16.0 0.0 1.7 1 0 0 1 1 1 1 PH domain FYVE PF01363.21 RLN87928.1 - 0.098 12.8 7.1 0.2 11.8 7.1 1.5 1 0 0 1 1 1 0 FYVE zinc finger TFIIA PF03153.13 RLN87929.1 - 2.6 7.9 21.1 2.9 7.8 21.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LMWPc PF01451.21 RLN87930.1 - 3.1e-10 40.6 0.0 3.6e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Peptidase_C1 PF00112.23 RLN87931.1 - 0.00086 19.5 0.0 0.4 10.7 0.0 2.4 2 0 0 2 2 2 2 Papain family cysteine protease BOP1NT PF08145.12 RLN87932.1 - 1.5e-77 261.0 4.6 2.1e-77 260.6 4.6 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 RLN87932.1 - 7.4e-30 102.6 10.3 1.9e-07 31.7 0.0 8.5 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN87932.1 - 7.4e-10 39.0 0.3 0.0047 17.2 0.0 4.9 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 RLN87932.1 - 0.0085 14.5 0.0 0.015 13.7 0.0 1.3 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 RLN87932.1 - 0.1 13.1 0.0 0.81 10.3 0.0 2.6 2 0 0 2 2 2 0 PQQ-like domain Ank_4 PF13637.6 RLN87934.1 - 1.8e-13 50.7 10.6 3.9e-08 33.7 1.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN87934.1 - 3.8e-10 40.2 0.5 7.9e-10 39.2 0.4 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN87934.1 - 2.1e-09 37.5 3.1 3.6e-08 33.5 0.5 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN87934.1 - 1.6e-08 34.1 0.3 0.0027 18.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 RLN87934.1 - 8.4e-07 29.2 2.3 0.025 15.0 0.3 3.3 4 0 0 4 4 4 2 Ankyrin repeat ELO PF01151.18 RLN87935.1 - 1.2e-40 139.6 23.8 2.3e-40 138.7 23.8 1.3 1 1 0 1 1 1 1 GNS1/SUR4 family CnrY PF17524.2 RLN87935.1 - 0.58 10.4 2.2 3.6 7.9 0.9 2.6 2 1 1 3 3 3 0 Anti-sigma factor CnrY ABC2_membrane PF01061.24 RLN87936.1 - 1.6e-26 93.1 16.0 2.1e-26 92.7 16.0 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN87936.1 - 3.2e-19 69.8 0.0 6.6e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN87936.1 - 0.00067 19.6 0.1 0.12 12.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN87936.1 - 0.00084 19.0 0.2 0.0023 17.6 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN87936.1 - 0.0043 17.3 0.1 0.018 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN87936.1 - 0.0056 17.1 0.2 0.024 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain ABC_ATPase PF09818.9 RLN87936.1 - 0.01 14.7 0.1 0.019 13.8 0.1 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class MeaB PF03308.16 RLN87936.1 - 0.032 13.2 0.1 0.054 12.5 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 RLN87936.1 - 0.036 13.8 0.0 0.8 9.4 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.18 RLN87936.1 - 0.038 13.4 0.4 0.091 12.1 0.0 1.8 2 0 0 2 2 1 0 FtsK/SpoIIIE family SMC_N PF02463.19 RLN87936.1 - 0.038 13.4 0.0 3 7.2 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RLN87936.1 - 0.039 14.0 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 RLN87936.1 - 0.046 13.3 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RLN87936.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 RLN87936.1 - 0.16 11.7 0.1 0.4 10.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RLN87936.1 - 0.17 12.0 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 RLN87936.1 - 0.18 12.3 0.0 0.81 10.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 RLN87936.1 - 0.21 10.9 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin SAT PF16073.5 RLN87936.1 - 0.22 11.2 2.1 0.35 10.6 0.4 2.1 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis AAA_23 PF13476.6 RLN87936.1 - 0.31 11.5 0.1 0.53 10.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 RLN87936.1 - 0.85 8.9 1.8 1.2 8.4 0.3 1.8 1 1 1 2 2 2 0 KaiC ABC2_membrane_3 PF12698.7 RLN87936.1 - 7.5 5.6 17.3 0.21 10.7 9.9 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein Cupin_8 PF13621.6 RLN87937.1 - 1.7e-38 132.8 0.0 8.5e-33 114.1 0.0 2.1 1 1 1 2 2 2 2 Cupin-like domain Cupin_4 PF08007.12 RLN87937.1 - 4.6e-14 52.6 0.4 1e-13 51.5 0.1 1.6 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 RLN87937.1 - 0.00029 21.2 0.0 0.00058 20.3 0.0 1.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 RLN87937.1 - 0.0035 17.0 0.0 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 RLN87937.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Cupin PA28_beta PF02252.18 RLN87939.1 - 1.5e-29 102.5 0.1 1.7e-18 66.7 0.0 2.2 2 0 0 2 2 2 2 Proteasome activator pa28 beta subunit Mur_ligase_M PF08245.12 RLN87940.1 - 1.6e-10 41.3 0.0 2.8e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 RLN87940.1 - 2.9e-06 27.5 0.4 5.5e-05 23.4 0.0 2.8 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain NA37 PF04245.13 RLN87940.1 - 0.039 13.4 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein Pkinase_Tyr PF07714.17 RLN87941.1 - 9.7e-50 169.2 0.0 2e-39 135.4 0.0 3.3 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN87941.1 - 4e-48 164.1 0.0 2.8e-38 131.8 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 RLN87941.1 - 0.008 15.0 0.0 0.018 13.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN87941.1 - 0.031 14.2 0.1 0.1 12.5 0.1 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 RLN87941.1 - 0.065 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family DUF3580 PF12117.8 RLN87942.1 - 0.044 14.0 0.0 0.068 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3580) GTP_CH_N PF12471.8 RLN87943.1 - 3.2e-71 239.1 0.5 1.4e-41 142.4 0.0 3.1 1 1 1 2 2 2 2 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 RLN87943.1 - 3.4e-13 49.5 0.0 5.3e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Adap_comp_sub PF00928.21 RLN87943.1 - 3.3e-07 30.0 0.0 4.7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 RLN87943.1 - 0.16 11.9 0.5 0.36 10.7 0.5 1.5 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Cyclin_N PF00134.23 RLN87944.1 - 5.3e-41 139.3 0.6 2.3e-38 130.8 0.2 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 RLN87944.1 - 3.6e-26 91.6 1.2 5.6e-26 91.0 0.3 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF383 PF04063.14 RLN87945.1 - 1.3e-42 145.6 0.1 2.1e-41 141.7 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 RLN87945.1 - 1.2e-20 73.1 0.2 3.4e-20 71.6 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF384) HEAT PF02985.22 RLN87945.1 - 0.0029 17.7 1.8 23 5.6 0.1 4.0 4 0 0 4 4 4 1 HEAT repeat Neurochondrin PF05536.11 RLN87945.1 - 0.044 12.1 0.6 14 3.9 0.0 3.1 2 1 1 3 3 3 0 Neurochondrin Proteasom_PSMB PF10508.9 RLN87945.1 - 0.084 11.4 0.2 12 4.3 0.2 2.8 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.6 RLN87945.1 - 0.6 10.7 3.2 36 5.0 0.0 3.7 4 0 0 4 4 4 0 HEAT-like repeat Arm PF00514.23 RLN87945.1 - 1.3 9.1 5.5 27 5.0 0.0 3.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat zf-C3HC4_3 PF13920.6 RLN87946.1 - 4.3e-10 39.3 11.4 4.3e-10 39.3 11.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 RLN87946.1 - 8.1e-09 36.0 0.4 4.8e-06 27.1 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN87946.1 - 1.3e-07 31.8 1.3 3.4e-06 27.2 0.2 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN87946.1 - 2e-07 31.4 0.4 9.4e-05 22.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN87946.1 - 1e-05 25.7 0.2 0.35 11.4 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 RLN87946.1 - 1.3e-05 25.2 0.0 0.61 10.8 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Prok-RING_4 PF14447.6 RLN87946.1 - 0.00044 20.1 14.5 0.0015 18.3 11.2 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 RLN87946.1 - 0.0022 18.3 11.2 0.0022 18.3 11.2 1.9 2 0 0 2 2 1 1 Ring finger domain PH PF00169.29 RLN87946.1 - 0.018 15.5 0.3 0.054 14.0 0.3 1.8 1 1 0 1 1 1 0 PH domain SpoIIIAH PF12685.7 RLN87946.1 - 0.033 14.0 2.5 2.5 7.9 0.1 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein zf-RING_5 PF14634.6 RLN87946.1 - 0.088 12.8 11.1 0.22 11.5 11.1 1.7 1 0 0 1 1 1 0 zinc-RING finger domain DZR PF12773.7 RLN87946.1 - 0.35 10.9 6.7 0.76 9.9 0.4 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-C3HC4_2 PF13923.6 RLN87946.1 - 0.62 9.9 12.2 1.3 8.9 12.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 RLN87946.1 - 1.7 8.5 13.6 0.63 9.9 8.7 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain CRAL_TRIO PF00650.20 RLN87947.1 - 2.1e-22 79.6 0.0 3.6e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 RLN87947.1 - 0.074 13.2 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF4560 PF15118.6 RLN87947.1 - 0.38 10.7 2.7 0.58 10.1 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4560) CDP-OH_P_transf PF01066.21 RLN87948.1 - 5.4e-11 43.1 0.1 5.4e-11 43.1 0.1 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Cad PF03596.13 RLN87948.1 - 0.033 14.1 0.5 0.078 12.9 0.5 1.6 1 0 0 1 1 1 0 Cadmium resistance transporter DUF1729 PF08354.10 RLN87948.1 - 0.058 12.3 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) VirB3 PF05101.13 RLN87948.1 - 1.1 9.5 5.5 13 6.1 2.7 2.7 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein EGF_2 PF07974.13 RLN87949.1 - 1.1 9.7 9.3 2.2 8.7 9.3 1.5 1 0 0 1 1 1 0 EGF-like domain SET PF00856.28 RLN87950.1 - 0.0011 19.3 0.0 0.0031 17.9 0.0 1.7 1 1 0 1 1 1 1 SET domain DUF445 PF04286.12 RLN87951.1 - 0.0014 18.5 1.9 0.0018 18.2 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Colicin PF01024.19 RLN87951.1 - 0.062 13.2 0.4 0.12 12.2 0.4 1.4 1 0 0 1 1 1 0 Colicin pore forming domain TipAS PF07739.13 RLN87951.1 - 0.11 13.1 1.4 0.47 11.0 1.3 2.3 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain DUF3835 PF12927.7 RLN87951.1 - 2.1 9.2 8.4 1.2 10.0 1.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3835) NAD_binding_11 PF14833.6 RLN87952.1 - 2.5e-28 98.8 0.1 8.5e-28 97.0 0.1 2.0 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 RLN87952.1 - 3.7e-22 79.2 0.2 8.3e-22 78.0 0.2 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DBD_Tnp_Mut PF03108.15 RLN87952.1 - 0.038 14.0 0.0 0.096 12.7 0.0 1.6 1 0 0 1 1 1 0 MuDR family transposase NAD_binding_11 PF14833.6 RLN87953.1 - 4.1e-29 101.3 0.1 2e-28 99.1 0.1 2.2 2 1 1 3 3 3 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 RLN87953.1 - 5.8e-27 94.8 0.3 9.5e-27 94.1 0.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase COPI_assoc PF08507.10 RLN87953.1 - 0.00032 20.7 2.3 0.0006 19.9 0.4 2.2 2 0 0 2 2 2 1 COPI associated protein ARS2 PF04959.13 RLN87953.1 - 0.084 13.2 4.0 0.14 12.5 4.0 1.3 1 0 0 1 1 1 0 Arsenite-resistance protein 2 MULE PF10551.9 RLN87955.1 - 1e-10 41.9 0.9 2e-10 40.9 0.9 1.5 1 0 0 1 1 1 1 MULE transposase domain Sulfatase PF00884.23 RLN87957.1 - 1.2e-24 87.2 0.0 1.7e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 RLN87957.1 - 1.5e-05 23.8 0.0 3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 RLN87957.1 - 8.8e-05 22.3 0.0 0.0008 19.1 0.1 2.1 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Lipase_GDSL_2 PF13472.6 RLN87960.1 - 2.9e-24 86.5 0.1 3.5e-24 86.2 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RLN87960.1 - 5.6e-18 65.6 0.0 7.7e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase LapA_dom PF06305.11 RLN87960.1 - 0.18 11.6 0.7 0.36 10.7 0.7 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TPD52 PF04201.15 RLN87961.1 - 0.078 12.6 0.3 0.53 9.9 0.0 2.2 2 0 0 2 2 2 0 Tumour protein D52 family Csm1_N PF18504.1 RLN87961.1 - 0.09 13.1 0.2 2.4 8.5 0.1 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF641 PF04859.12 RLN87961.1 - 0.099 13.0 6.5 10 6.5 0.1 3.5 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) CCDC144C PF14915.6 RLN87961.1 - 0.4 9.8 8.2 0.1 11.7 1.2 2.1 1 1 0 2 2 2 0 CCDC144C protein coiled-coil region Fez1 PF06818.15 RLN87961.1 - 0.75 10.2 10.0 1.4 9.4 9.4 1.7 1 1 1 2 2 2 0 Fez1 APG6_N PF17675.1 RLN87961.1 - 4.1 7.9 9.1 9.3 6.8 9.1 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region MscS_porin PF12795.7 RLN87961.1 - 4.5 6.8 20.9 2.8 7.4 10.1 2.4 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Ank_2 PF12796.7 RLN87962.1 - 5e-62 206.5 1.3 9.9e-12 45.3 0.0 5.3 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN87962.1 - 1e-50 163.8 4.9 9.2e-05 22.6 0.0 10.3 10 0 0 10 10 10 10 Ankyrin repeat Ank_4 PF13637.6 RLN87962.1 - 7.9e-47 157.1 7.3 4.2e-09 36.8 0.0 6.9 3 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 RLN87962.1 - 6.4e-46 152.9 13.0 0.00024 21.4 0.0 10.4 10 0 0 10 10 10 10 Ankyrin repeat Ank_5 PF13857.6 RLN87962.1 - 1.5e-39 133.6 13.2 3.9e-07 30.2 0.1 9.7 3 2 8 11 11 11 10 Ankyrin repeats (many copies) DUF3107 PF11305.8 RLN87962.1 - 0.03 14.6 0.1 9.1 6.6 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3107) Cdc6_C PF09079.11 RLN87963.1 - 0.0035 17.3 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain EF-hand_7 PF13499.6 RLN87964.1 - 1.9e-09 37.8 0.0 0.28 11.7 0.0 6.5 6 0 0 6 6 6 3 EF-hand domain pair EF-hand_6 PF13405.6 RLN87964.1 - 8.5e-05 22.2 0.0 32 4.8 0.0 7.2 9 0 0 9 9 9 1 EF-hand domain EF-hand_1 PF00036.32 RLN87964.1 - 0.037 13.6 0.0 14 5.6 0.0 4.2 3 0 0 3 3 3 0 EF hand AMP-binding PF00501.28 RLN87965.1 - 2e-76 257.3 0.0 2.3e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN87965.1 - 0.0082 17.1 0.1 0.017 16.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF5115 PF17142.4 RLN87965.1 - 0.23 11.1 0.0 0.41 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5115) Sigma70_ner PF04546.13 RLN87966.1 - 0.032 14.1 0.1 0.032 14.1 0.1 3.3 3 0 0 3 3 3 0 Sigma-70, non-essential region EF-hand_6 PF13405.6 RLN87967.1 - 3.2e-05 23.5 0.0 0.042 13.8 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RLN87967.1 - 0.00018 20.8 0.0 0.009 15.5 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 RLN87967.1 - 0.00085 19.7 0.1 2.1 8.9 0.0 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN87967.1 - 0.0079 15.6 1.0 0.092 12.3 0.2 2.9 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 RLN87967.1 - 0.02 15.2 0.2 0.44 10.9 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.6 RLN87967.1 - 0.063 13.1 0.1 0.3 11.0 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain pair FYVE PF01363.21 RLN87968.1 - 4e-13 49.3 8.9 7.1e-13 48.5 8.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger TPR_2 PF07719.17 RLN87968.1 - 8.4e-08 31.8 0.0 0.013 15.6 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN87968.1 - 4.3e-07 29.5 0.0 9.4e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.28 RLN87968.1 - 3.6e-06 26.5 0.0 0.088 12.7 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN87968.1 - 6.1e-06 26.8 0.2 6.1e-06 26.8 0.2 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN87968.1 - 1.7e-05 25.2 0.1 1.7e-05 25.2 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN87968.1 - 1.8e-05 24.6 0.0 0.0098 16.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN87968.1 - 0.007 17.1 7.0 0.052 14.4 0.0 4.4 3 1 1 4 4 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN87968.1 - 0.0096 16.2 0.1 0.039 14.3 0.1 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN87968.1 - 0.024 15.0 0.0 0.28 11.6 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 RLN87968.1 - 0.054 13.5 0.6 4.5 7.5 0.4 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat Ank_5 PF13857.6 RLN87968.1 - 0.055 13.8 0.1 1.8 9.0 0.0 2.6 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN87968.1 - 0.063 13.9 0.0 13 6.5 0.0 2.3 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) OrfB_Zn_ribbon PF07282.11 RLN87968.1 - 0.1 12.5 1.3 0.26 11.2 1.3 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Acetyltransf_11 PF13720.6 RLN87968.1 - 0.16 12.4 0.8 0.54 10.7 0.1 2.3 2 0 0 2 2 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 PPP4R2 PF09184.11 RLN87968.1 - 0.46 10.0 10.4 0.91 9.1 10.4 1.5 1 0 0 1 1 1 0 PPP4R2 TPR_10 PF13374.6 RLN87968.1 - 0.91 9.5 3.2 32 4.6 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SDA1 PF05285.12 RLN87968.1 - 3 7.2 13.8 6.1 6.2 13.8 1.5 1 0 0 1 1 1 0 SDA1 OrfB_Zn_ribbon PF07282.11 RLN87969.1 - 9.5e-09 35.1 1.0 2.5e-08 33.7 1.0 1.7 1 1 0 1 1 1 1 Putative transposase DNA-binding domain malic PF00390.19 RLN87970.1 - 1.7e-35 122.5 0.0 3.2e-35 121.6 0.0 1.5 1 1 0 1 1 1 1 Malic enzyme, N-terminal domain Mito_carr PF00153.27 RLN87971.1 - 1.4e-18 66.6 10.3 4.1e-09 36.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein UPF0054 PF02130.17 RLN87972.1 - 6.7e-23 80.9 0.0 8e-23 80.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 Zn_ribbon_SprT PF17283.2 RLN87974.1 - 0.12 12.3 4.1 0.17 11.8 0.3 2.5 1 1 1 2 2 2 0 SprT-like zinc ribbon domain DUF3301 PF11743.8 RLN87974.1 - 0.16 11.7 0.6 12 5.6 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3301) FYVE PF01363.21 RLN87974.1 - 0.48 10.6 9.1 0.4 10.9 7.5 1.7 1 1 0 1 1 1 0 FYVE zinc finger Tnp_zf-ribbon_2 PF13842.6 RLN87974.1 - 2.5 9.0 8.7 0.31 11.9 4.2 1.9 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon TatD_DNase PF01026.21 RLN87977.1 - 7.7e-59 199.1 0.0 9.3e-59 198.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 RLN87977.1 - 0.0012 18.7 0.0 0.003 17.4 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase AAA_18 PF13238.6 RLN87978.1 - 1.2e-09 38.8 0.0 3.1e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 RLN87978.1 - 4.8e-09 36.7 0.1 8.9e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RLN87978.1 - 1.1e-05 25.7 0.3 4e-05 23.8 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RLN87978.1 - 0.0024 18.1 0.0 0.12 12.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain CoaE PF01121.20 RLN87978.1 - 0.0084 15.8 0.2 0.052 13.2 0.0 2.3 2 2 0 2 2 2 1 Dephospho-CoA kinase NB-ARC PF00931.22 RLN87978.1 - 0.014 14.6 0.0 1.1 8.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 RLN87978.1 - 0.019 14.3 0.3 1.1 8.6 0.0 2.6 3 0 0 3 3 3 0 KaiC dNK PF01712.19 RLN87978.1 - 0.026 14.4 0.3 0.16 11.8 0.3 2.3 1 1 0 1 1 1 0 Deoxynucleoside kinase IMUP PF15761.5 RLN87978.1 - 0.47 11.2 5.9 0.77 10.5 5.9 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein SnoaL PF07366.12 RLN87981.1 - 5.9e-12 45.5 1.1 1.4e-11 44.3 0.0 2.1 3 0 0 3 3 3 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 RLN87981.1 - 3.6e-08 34.0 0.0 7.7e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like domain bZIP_1 PF00170.21 RLN87981.1 - 0.0016 18.5 3.2 0.0016 18.5 3.2 2.0 2 0 0 2 2 2 1 bZIP transcription factor KLRAQ PF10205.9 RLN87981.1 - 0.34 11.2 5.9 0.57 10.5 5.9 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein FapA PF03961.13 RLN87981.1 - 0.51 8.9 3.0 0.69 8.4 3.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A bZIP_2 PF07716.15 RLN87981.1 - 0.86 9.7 7.2 0.63 10.2 3.8 2.1 1 1 1 2 2 2 0 Basic region leucine zipper FAP206 PF12018.8 RLN87982.1 - 4.5e-82 275.7 0.0 2.6e-81 273.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function VPS13_mid_rpt PF16910.5 RLN87982.1 - 0.04 13.3 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 Repeating coiled region of VPS13 CH PF00307.31 RLN87983.1 - 7.2e-45 151.6 4.1 6.9e-22 77.7 0.0 3.5 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RLN87983.1 - 6.3e-12 45.2 0.1 6e-07 29.2 0.0 2.7 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_7 PF13499.6 RLN87983.1 - 9.5e-08 32.4 7.8 1.2e-07 32.1 5.3 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN87983.1 - 4.8e-07 29.2 4.9 0.00028 20.6 0.3 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RLN87983.1 - 1.9e-06 27.0 7.9 5.3e-05 22.5 0.7 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RLN87983.1 - 3.6e-05 23.5 7.9 0.018 14.9 2.9 2.9 1 1 1 2 2 2 2 EF-hand domain pair CH_2 PF06294.11 RLN87983.1 - 0.0015 18.7 0.5 0.18 11.9 0.0 2.9 2 0 0 2 2 2 1 CH-like domain in sperm protein Spectrin PF00435.21 RLN87983.1 - 0.084 13.4 0.3 0.084 13.4 0.3 5.6 4 2 1 5 5 5 0 Spectrin repeat EF-hand_5 PF13202.6 RLN87983.1 - 1.1 8.8 5.1 0.3 10.7 0.3 2.5 2 0 0 2 2 2 0 EF hand MerR-DNA-bind PF09278.11 RLN87983.1 - 1.6 9.3 5.5 17 6.0 0.0 4.6 4 0 0 4 4 4 0 MerR, DNA binding LUC7 PF03194.15 RLN87983.1 - 2.3 7.8 17.5 0.71 9.5 11.6 2.8 2 1 0 2 2 2 0 LUC7 N_terminus Fib_alpha PF08702.10 RLN87983.1 - 3.9 7.6 15.1 4.7 7.4 1.3 4.3 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Sel1 PF08238.12 RLN87984.1 - 5.1e-32 109.6 22.7 6.3e-06 26.7 0.2 10.8 12 0 0 12 12 12 8 Sel1 repeat E1-E2_ATPase PF00122.20 RLN87985.1 - 1.1e-49 168.5 2.1 1.1e-49 168.5 2.1 2.7 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 RLN87985.1 - 3e-49 167.2 0.1 3e-49 167.2 0.1 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 RLN87985.1 - 3e-24 86.5 1.1 3.5e-23 83.0 0.2 3.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN87985.1 - 1.4e-16 60.3 0.1 7.6e-16 58.0 0.0 2.3 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 RLN87985.1 - 2.5e-15 55.9 0.0 4.4e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RLN87985.1 - 0.00018 21.3 0.6 0.00037 20.3 0.6 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4870 PF09685.10 RLN87985.1 - 3 8.0 5.7 3.9 7.6 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4870) cobW PF02492.19 RLN87986.1 - 2.1e-53 180.5 0.1 3.7e-53 179.7 0.1 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 RLN87986.1 - 1.7e-20 72.7 0.0 3.2e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 RLN87986.1 - 0.0014 18.3 0.1 0.54 9.8 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RLN87986.1 - 0.0016 18.4 0.1 0.29 11.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase KdpD PF02702.17 RLN87986.1 - 0.0017 17.8 0.1 0.0028 17.1 0.1 1.3 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain AAA_16 PF13191.6 RLN87986.1 - 0.0054 17.1 0.1 0.015 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain SRPRB PF09439.10 RLN87986.1 - 0.018 14.5 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 RLN87986.1 - 0.018 15.3 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 RLN87986.1 - 0.049 13.7 0.0 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 RLN87986.1 - 0.052 12.6 0.0 0.084 11.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 RLN87986.1 - 0.059 13.1 0.2 0.14 12.0 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 RLN87986.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RLN87986.1 - 0.12 12.9 0.6 0.27 11.8 0.1 1.8 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 RLN87986.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF3099 PF11298.8 RLN87987.1 - 0.09 12.9 0.8 0.6 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) Ald_deCOase PF11266.8 RLN87987.1 - 0.28 10.9 0.7 0.49 10.0 0.1 1.7 1 1 1 2 2 2 0 Long-chain fatty aldehyde decarbonylase CDC45 PF02724.14 RLN87988.1 - 0.11 10.8 1.2 0.16 10.3 1.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.10 RLN87988.1 - 6.3 7.1 8.2 13 6.1 8.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 COPI_C PF06957.11 RLN87990.1 - 0.062 12.0 2.4 0.12 11.1 2.4 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus EF-hand_8 PF13833.6 RLN87990.1 - 0.09 12.6 0.3 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair DUF5131 PF07505.11 RLN87993.1 - 0.057 12.9 0.1 0.065 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF5131) zf-BED PF02892.15 RLN87994.1 - 1.5e-09 37.8 5.7 3.3e-05 23.8 2.5 2.6 2 0 0 2 2 2 2 BED zinc finger zf-C2HE PF16278.5 RLN87994.1 - 0.14 12.7 1.3 0.34 11.4 1.3 1.7 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Zn_ribbon_SprT PF17283.2 RLN87994.1 - 0.65 10.0 4.4 6.2 6.8 0.8 2.5 2 0 0 2 2 2 0 SprT-like zinc ribbon domain YbjQ_1 PF01906.17 RLN87995.1 - 0.12 13.0 0.1 0.21 12.3 0.1 1.4 1 0 0 1 1 1 0 Putative heavy-metal-binding Cpn60_TCP1 PF00118.24 RLN87996.1 - 1.5e-100 337.2 0.0 1.9e-100 336.8 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ATP-gua_Ptrans PF00217.19 RLN87998.1 - 2e-75 252.9 0.0 2.6e-75 252.5 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 RLN87998.1 - 1.3e-28 99.2 0.0 2.3e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain SpoIIE PF07228.12 RLN87999.1 - 0.00071 19.6 0.0 0.44 10.4 0.0 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) MtN3_slv PF03083.16 RLN88000.1 - 4.7e-27 93.8 3.4 5.5e-17 61.6 0.3 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RLN88000.1 - 1.1 9.1 12.8 4.5 7.1 0.1 4.4 4 1 1 5 5 5 0 PQ loop repeat DUF3087 PF11286.8 RLN88000.1 - 4.3 6.8 5.0 16 4.9 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3087) Ribosomal_L20 PF00453.18 RLN88001.1 - 2e-40 137.2 2.6 2.6e-40 136.8 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 CDP-OH_P_transf PF01066.21 RLN88002.1 - 1e-14 55.1 0.0 1e-14 55.1 0.0 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase UQ_con PF00179.26 RLN88004.1 - 1.1e-10 41.3 0.1 1.9e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3450 PF11932.8 RLN88005.1 - 0.0056 16.0 1.3 0.0056 16.0 1.3 3.3 2 1 0 3 3 3 1 Protein of unknown function (DUF3450) IFP_35_N PF07334.13 RLN88005.1 - 0.42 10.7 12.9 3.5 7.8 0.4 4.1 4 0 0 4 4 4 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF2937 PF11157.8 RLN88005.1 - 1.7 8.4 5.8 13 5.5 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2937) zf-C3HC4_3 PF13920.6 RLN88006.1 - 4.3e-10 39.3 11.4 4.3e-10 39.3 11.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 RLN88006.1 - 1e-08 35.6 0.6 4.7e-06 27.1 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN88006.1 - 6.3e-08 33.0 0.8 0.00011 22.6 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN88006.1 - 2.7e-07 30.7 2.3 4.5e-06 26.8 0.6 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 RLN88006.1 - 6.7e-07 29.5 0.3 0.04 14.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 RLN88006.1 - 8.7e-06 25.7 0.0 0.46 11.2 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Prok-RING_4 PF14447.6 RLN88006.1 - 0.00044 20.1 14.5 0.0015 18.3 11.2 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 RLN88006.1 - 0.0022 18.3 11.2 0.0022 18.3 11.2 1.9 2 0 0 2 2 1 1 Ring finger domain PH PF00169.29 RLN88006.1 - 0.0087 16.6 0.3 0.022 15.2 0.3 1.7 1 0 0 1 1 1 1 PH domain zf-RING_5 PF14634.6 RLN88006.1 - 0.088 12.8 11.1 0.22 11.5 11.1 1.7 1 0 0 1 1 1 0 zinc-RING finger domain SpoIIIAH PF12685.7 RLN88006.1 - 0.17 11.7 2.1 4.7 7.0 0.1 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein DZR PF12773.7 RLN88006.1 - 0.33 11.0 6.7 0.76 9.9 0.4 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-C3HC4_2 PF13923.6 RLN88006.1 - 0.6 10.0 12.2 1.3 8.9 12.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 RLN88006.1 - 1.7 8.5 13.6 0.63 9.9 8.7 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain NAD_binding_11 PF14833.6 RLN88007.1 - 2.6e-64 214.9 0.7 2.3e-33 115.0 0.0 2.9 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 RLN88007.1 - 3.7e-52 176.7 2.3 1e-27 97.2 0.1 2.4 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase AbrB PF05145.12 RLN88007.1 - 0.024 13.6 1.7 1.5 7.7 0.2 2.3 2 0 0 2 2 2 0 Transition state regulatory protein AbrB TAXi_C PF14541.6 RLN88007.1 - 0.081 12.7 0.0 12 5.6 0.0 2.5 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal DBD_Tnp_Mut PF03108.15 RLN88007.1 - 0.086 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 MuDR family transposase YtxH PF12732.7 RLN88007.1 - 0.19 12.3 5.1 9 6.9 0.2 3.3 3 0 0 3 3 3 0 YtxH-like protein CDP-OH_P_transf PF01066.21 RLN88008.1 - 4.6e-11 43.3 0.1 4.6e-11 43.3 0.1 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Cad PF03596.13 RLN88008.1 - 0.015 15.2 0.5 0.037 13.9 0.5 1.6 1 0 0 1 1 1 0 Cadmium resistance transporter VirB3 PF05101.13 RLN88008.1 - 0.98 9.7 6.8 2.7 8.3 2.0 2.7 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein CRAL_TRIO PF00650.20 RLN88009.1 - 3.1e-22 79.0 0.0 5.3e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain DUF4560 PF15118.6 RLN88009.1 - 0.4 10.6 2.7 0.58 10.1 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4560) XAP5 PF04921.14 RLN88011.1 - 4.2e-32 111.9 16.0 6.8e-31 108.0 16.0 2.0 1 1 0 1 1 1 1 XAP5, circadian clock regulator Phostensin PF13914.6 RLN88011.1 - 0.13 12.9 0.2 0.13 12.9 0.2 2.3 2 1 0 2 2 2 0 Phostensin PP1-binding and SH3-binding region Aldedh PF00171.22 RLN88012.1 - 2.6e-30 105.3 0.0 3e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PrgU PF09627.10 RLN88012.1 - 0.083 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 PrgU-like protein NTP_transf_4 PF13562.6 RLN88012.1 - 0.16 12.1 0.0 0.3 11.3 0.0 1.5 1 1 0 1 1 1 0 Sugar nucleotidyl transferase Cyclin_N PF00134.23 RLN88013.1 - 2.2e-41 140.6 0.8 9.6e-39 132.0 0.2 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 RLN88013.1 - 3.1e-26 91.8 2.0 3.8e-26 91.5 0.4 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF383 PF04063.14 RLN88014.1 - 2.6e-41 141.4 0.1 4.8e-40 137.3 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 RLN88014.1 - 1.2e-20 73.1 0.2 3.5e-20 71.6 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF384) HEAT PF02985.22 RLN88014.1 - 0.0029 17.7 1.8 23 5.6 0.1 4.1 4 0 0 4 4 4 1 HEAT repeat Neurochondrin PF05536.11 RLN88014.1 - 0.059 11.7 0.9 14 3.9 0.0 3.1 2 1 1 3 3 3 0 Neurochondrin HEAT_EZ PF13513.6 RLN88014.1 - 0.67 10.5 3.7 36 5.0 0.0 3.7 4 0 0 4 4 4 0 HEAT-like repeat Arm PF00514.23 RLN88014.1 - 1 9.5 5.1 25 5.1 0.0 3.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Mitofilin PF09731.9 RLN88014.1 - 3 6.6 8.1 4.8 5.9 8.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Adap_comp_sub PF00928.21 RLN88015.1 - 7.4e-08 32.1 0.0 9.6e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 RLN88015.1 - 1.5e-06 28.2 0.1 2.4e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain GTP_CH_N PF12471.8 RLN88016.1 - 1.3e-42 145.7 0.0 6.3e-42 143.5 0.0 2.0 2 0 0 2 2 2 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 RLN88016.1 - 6.5e-14 51.8 0.0 9.4e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II SET PF00856.28 RLN88017.1 - 0.002 18.6 0.0 0.0054 17.1 0.0 1.7 1 1 0 1 1 1 1 SET domain Sad1_UNC PF07738.13 RLN88018.1 - 1.9e-11 44.1 0.0 3.9e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal EF-hand_5 PF13202.6 RLN88020.1 - 1.8e-08 33.5 0.1 1.4e-06 27.5 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RLN88020.1 - 2.3e-07 30.2 0.1 0.00037 20.2 0.0 3.7 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 RLN88020.1 - 2.5e-07 29.8 0.0 6.8e-05 22.1 0.0 3.3 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 RLN88020.1 - 6e-07 29.8 0.0 1.4e-05 25.5 0.0 2.8 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 RLN88020.1 - 0.00028 20.7 0.0 0.0057 16.5 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair ZZ PF00569.17 RLN88020.1 - 0.00072 19.3 8.1 0.00072 19.3 8.1 2.7 2 1 0 2 2 2 1 Zinc finger, ZZ type PAP_assoc PF03828.19 RLN88025.1 - 6.2e-13 48.8 0.0 1.2e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 RLN88025.1 - 0.0079 16.5 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 RLN88025.1 - 0.076 13.1 0.0 0.23 11.6 0.0 1.8 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase LAMTOR PF15454.6 RLN88025.1 - 2.3 8.9 4.2 9 7.0 0.0 3.0 3 0 0 3 3 3 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator XPC-binding PF09280.11 RLN88026.1 - 0.0096 15.6 28.5 0.038 13.7 12.9 2.8 1 1 1 2 2 2 2 XPC-binding domain STI1 PF17830.1 RLN88026.1 - 0.039 13.9 29.8 0.16 11.9 25.1 2.4 1 1 1 2 2 2 0 STI1 domain PDZ_6 PF17820.1 RLN88027.1 - 3.3e-09 36.5 0.1 8.3e-09 35.2 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RLN88027.1 - 7.4e-07 29.4 0.0 1.9e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RLN88027.1 - 0.0004 20.7 0.0 0.002 18.4 0.0 2.2 2 0 0 2 2 2 1 PDZ domain RET_CLD3 PF17812.1 RLN88034.1 - 0.019 15.2 0.0 0.026 14.8 0.0 1.2 1 0 0 1 1 1 0 RET Cadherin like domain 3 DUF1653 PF07866.11 RLN88034.1 - 0.14 12.5 0.1 0.34 11.3 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1653) Methyltransf_25 PF13649.6 RLN88035.1 - 3.8e-08 33.9 0.0 5.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN88035.1 - 1.4e-06 28.2 0.0 1.8e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN88035.1 - 2.7e-06 28.0 0.0 4.3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN88035.1 - 9e-06 26.3 0.0 1.4e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN88035.1 - 4.6e-05 23.3 0.0 6.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 RLN88035.1 - 0.00075 19.3 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 RLN88035.1 - 0.00098 18.8 0.3 0.0021 17.7 0.1 1.7 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 RLN88035.1 - 0.0013 18.1 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NTPase_P4 PF11602.8 RLN88035.1 - 0.033 13.4 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 CMAS PF02353.20 RLN88035.1 - 0.076 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ribosomal_L23eN PF03939.13 RLN88036.1 - 0.085 13.1 0.2 0.14 12.4 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein L23, N-terminal domain Anp1 PF03452.14 RLN88037.1 - 1.7e-39 135.8 2.3 2.1e-26 92.9 0.2 3.0 3 0 0 3 3 3 3 Anp1 zf-C2H2 PF00096.26 RLN88038.1 - 0.00044 20.6 0.2 0.00091 19.6 0.2 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN88038.1 - 0.0076 17.0 0.4 0.02 15.7 0.4 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf_C2H2_6 PF18450.1 RLN88038.1 - 0.013 15.1 0.1 0.039 13.6 0.1 1.8 1 0 0 1 1 1 0 Zinc Finger domain ARS2 PF04959.13 RLN88038.1 - 0.016 15.6 0.0 0.016 15.6 0.0 3.1 3 0 0 3 3 3 0 Arsenite-resistance protein 2 zf-BED PF02892.15 RLN88038.1 - 0.036 14.1 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 BED zinc finger DUF3793 PF12672.7 RLN88038.1 - 0.23 11.5 1.3 0.49 10.4 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) ZYG-11_interact PF05884.12 RLN88038.1 - 1.4 8.3 2.5 2.5 7.4 2.5 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF1676 PF07898.13 RLN88038.1 - 1.5 8.8 4.4 4.6 7.2 4.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Mrr_N PF14338.6 RLN88038.1 - 8.6 6.6 7.6 1.2 9.3 2.5 2.2 2 0 0 2 2 2 0 Mrr N-terminal domain Ank_2 PF12796.7 RLN88039.1 - 9e-84 276.2 20.4 4.1e-12 46.5 0.3 7.3 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN88039.1 - 1.4e-71 235.9 13.8 6.5e-09 36.2 0.0 9.3 3 2 8 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 RLN88039.1 - 3.1e-53 176.0 27.8 5.5e-05 23.4 0.0 14.0 14 0 0 14 14 14 11 Ankyrin repeat Ank_5 PF13857.6 RLN88039.1 - 2.2e-52 174.4 18.9 4.1e-07 30.2 0.1 12.7 1 1 12 13 13 13 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN88039.1 - 8.4e-46 148.7 6.9 0.065 13.8 0.0 13.8 13 0 0 13 13 13 13 Ankyrin repeat Pkinase PF00069.25 RLN88039.1 - 4.7e-09 36.0 0.0 3.4e-08 33.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN88039.1 - 2.7e-07 30.1 0.0 1.7e-05 24.2 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1949 PF09186.11 RLN88039.1 - 0.0025 17.7 0.1 8 6.4 0.0 5.1 5 0 0 5 5 5 1 Domain of unknown function (DUF1949) PK_C PF02887.16 RLN88039.1 - 0.021 15.1 5.8 26 5.1 0.0 5.3 4 2 1 5 5 5 0 Pyruvate kinase, alpha/beta domain Atu4866 PF11512.8 RLN88039.1 - 0.059 13.8 0.0 1.1e+02 3.2 0.0 4.6 6 0 0 6 6 6 0 Agrobacterium tumefaciens protein Atu4866 PH PF00169.29 RLN88040.1 - 4.1e-18 65.8 0.0 1.6e-05 25.3 0.0 3.8 3 1 0 3 3 3 3 PH domain PDZ_6 PF17820.1 RLN88040.1 - 1.8e-06 27.7 0.0 4.1e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RLN88040.1 - 2.6e-06 27.7 0.0 6.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PH_11 PF15413.6 RLN88040.1 - 0.00046 20.6 0.2 0.45 11.0 0.0 4.1 4 1 0 4 4 4 1 Pleckstrin homology domain His_biosynth PF00977.21 RLN88041.1 - 2.1e-43 148.4 0.5 1.5e-42 145.6 0.5 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 RLN88041.1 - 0.004 16.3 0.0 0.0099 15.0 0.1 1.6 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) YdaT_toxin PF06254.11 RLN88042.1 - 0.21 12.2 2.2 5.5 7.6 0.0 3.4 3 1 0 3 3 3 0 Putative bacterial toxin ydaT HisKA PF00512.25 RLN88042.1 - 0.39 10.8 11.4 3.2 7.8 0.2 4.7 4 2 1 5 5 5 0 His Kinase A (phospho-acceptor) domain DUF155 PF02582.14 RLN88042.1 - 5.6 7.0 8.4 57 3.7 7.0 3.0 1 1 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 Serine_rich PF08824.10 RLN88042.1 - 5.8 6.9 26.9 0.045 13.8 9.4 4.1 2 2 2 4 4 4 0 Serine rich protein interaction domain Pkinase_Tyr PF07714.17 RLN88043.1 - 2.4e-29 102.4 0.0 4e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN88043.1 - 2.2e-24 86.2 0.0 3.7e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN88044.1 - 1.4e-42 145.8 0.0 2.3e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN88044.1 - 9.2e-38 130.1 0.0 1.8e-37 129.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.23 RLN88044.1 - 2.2e-21 75.2 14.5 0.035 14.2 0.0 11.7 12 0 0 12 12 12 6 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 RLN88044.1 - 2.4e-10 40.3 0.0 0.45 10.6 0.0 6.3 4 2 3 7 7 7 3 Spinocerebellar ataxia type 10 protein domain GatB_Yqey PF02637.18 RLN88044.1 - 1.4e-07 31.5 2.4 0.77 9.6 0.1 6.4 2 1 5 8 8 8 3 GatB domain HEAT_2 PF13646.6 RLN88044.1 - 2.9e-06 27.6 5.4 0.00087 19.6 1.0 6.6 4 2 3 7 7 6 2 HEAT repeats HTH_7 PF02796.15 RLN88044.1 - 6.1e-06 26.2 10.0 1.8 8.7 0.0 8.2 9 0 0 9 9 9 1 Helix-turn-helix domain of resolvase HEAT_EZ PF13513.6 RLN88044.1 - 9.5e-05 22.8 11.8 0.3 11.7 0.3 6.3 5 2 1 6 6 5 2 HEAT-like repeat GerE PF00196.19 RLN88044.1 - 0.0013 18.2 4.7 18 5.0 0.0 6.6 8 0 0 8 8 8 0 Bacterial regulatory proteins, luxR family HEAT PF02985.22 RLN88044.1 - 0.029 14.6 4.9 22 5.7 0.0 6.2 7 0 0 7 7 4 0 HEAT repeat Pkinase_fungal PF17667.1 RLN88044.1 - 0.087 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF4476 PF14771.6 RLN88044.1 - 0.1 12.9 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) FtsK_SpoIIIE PF01580.18 RLN88044.1 - 1.7 8.0 6.0 25 4.1 0.1 4.5 3 1 2 6 6 6 0 FtsK/SpoIIIE family Arm-DNA-bind_3 PF13356.6 RLN88044.1 - 2.2 8.7 10.9 89 3.6 0.1 6.0 6 0 0 6 6 6 0 Arm DNA-binding domain Rrp44_S1 PF17215.3 RLN88045.1 - 0.019 14.9 1.9 0.022 14.7 0.4 1.8 1 1 1 2 2 2 0 S1 domain EGF_2 PF07974.13 RLN88046.1 - 0.00069 19.9 3.3 0.0016 18.8 3.3 1.6 1 0 0 1 1 1 1 EGF-like domain CbtB PF09489.10 RLN88046.1 - 0.016 15.3 0.2 0.026 14.6 0.2 1.3 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) EB PF01683.18 RLN88046.1 - 0.082 13.2 3.4 0.13 12.6 3.4 1.3 1 0 0 1 1 1 0 EB module RskA PF10099.9 RLN88046.1 - 0.1 12.9 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TGBp3 PF02495.17 RLN88046.1 - 2.7 7.7 5.7 0.94 9.2 0.5 2.2 2 0 0 2 2 2 0 Triple gene block 3 Ldl_recept_a PF00057.18 RLN88046.1 - 6.7 7.0 11.7 23 5.3 0.3 2.3 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A SKN1 PF03935.15 RLN88047.1 - 1.6e-54 185.2 25.8 5.8e-36 124.0 12.4 5.0 2 2 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Dimer_Tnp_hAT PF05699.14 RLN88048.1 - 2.2e-15 56.2 0.0 8.4e-15 54.3 0.0 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 RLN88048.1 - 9e-05 22.4 0.0 0.00021 21.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) PhoLip_ATPase_C PF16212.5 RLN88050.1 - 2e-27 96.6 9.9 2e-27 96.6 9.9 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 RLN88050.1 - 2.4e-13 50.0 0.0 1.3e-12 47.6 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RLN88050.1 - 3.5e-13 49.5 0.2 3.5e-13 49.5 0.2 1.9 2 0 0 2 2 2 1 E1-E2 ATPase PhoLip_ATPase_N PF16209.5 RLN88050.1 - 1.1e-08 34.6 0.1 2.8e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RLN88050.1 - 0.032 14.5 0.2 13 6.0 0.0 2.7 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Gloverin PF10793.9 RLN88050.1 - 0.052 13.4 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 Gloverin-like protein RabGAP-TBC PF00566.18 RLN88051.1 - 5.5e-35 121.0 0.0 7.4e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Metallophos PF00149.28 RLN88052.1 - 1.5e-25 90.9 0.0 2.4e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CAP_GLY PF01302.25 RLN88052.1 - 1.1e-12 47.7 0.1 1.2e-11 44.4 0.0 2.5 2 0 0 2 2 2 1 CAP-Gly domain PPP5 PF08321.12 RLN88052.1 - 4e-07 30.2 0.0 7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 PPP5 TPR repeat region Aldo_ket_red PF00248.21 RLN88053.1 - 1.9e-65 221.0 0.0 2.2e-65 220.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_4 PF02390.17 RLN88055.1 - 9.8e-45 152.1 0.0 2.7e-43 147.4 0.0 2.0 1 1 1 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.6 RLN88055.1 - 0.00085 20.0 0.0 0.0037 17.9 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 RLN88055.1 - 0.003 17.1 0.0 0.012 15.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 RLN88055.1 - 0.01 16.5 0.1 0.093 13.4 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 RLN88055.1 - 0.017 15.9 0.2 0.12 13.2 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain Phtf-FEM1B_bdg PF12129.8 RLN88056.1 - 1.2e-20 73.9 0.0 1.8e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Male germ-cell putative homeodomain transcription factor LicD PF04991.13 RLN88056.1 - 3.1e-09 37.3 0.6 4.7e-09 36.7 0.6 1.3 1 0 0 1 1 1 1 LicD family Lung_7-TM_R PF06814.13 RLN88056.1 - 1.3 8.2 4.7 4.6 6.4 0.2 2.1 1 1 1 2 2 2 0 Lung seven transmembrane receptor Beach PF02138.18 RLN88057.1 - 5.6e-91 304.7 0.0 8.9e-91 304.1 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain ELMO_CED12 PF04727.13 RLN88057.1 - 2.4e-32 112.5 0.0 5e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF4704 PF15787.5 RLN88057.1 - 4e-15 55.8 0.0 9.8e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 RLN88057.1 - 1.9e-09 37.5 0.0 3.7e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 RLN88057.1 - 8.5e-08 32.5 0.0 2.7e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 RLN88057.1 - 0.0037 18.1 4.2 4.2 8.4 0.2 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Mob1_phocein PF03637.17 RLN88058.1 - 1.2e-62 210.9 0.2 1.6e-62 210.5 0.2 1.2 1 0 0 1 1 1 1 Mob1/phocein family DUF4711 PF15829.5 RLN88058.1 - 0.043 13.8 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) Myb_DNA-binding PF00249.31 RLN88060.1 - 5e-05 23.4 0.0 8.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Tli4_N PF18443.1 RLN88060.1 - 0.053 13.9 0.0 0.11 12.9 0.0 1.6 2 0 0 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain Myb_DNA-binding PF00249.31 RLN88061.1 - 4e-10 39.7 0.0 6.6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN88061.1 - 0.0045 17.2 0.1 0.0078 16.4 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2390 PF09523.10 RLN88061.1 - 0.11 12.8 1.1 0.16 12.3 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) MULE PF10551.9 RLN88063.1 - 1.1e-11 45.0 0.0 2.2e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain SET PF00856.28 RLN88064.1 - 2.1e-06 28.2 0.1 3.8e-05 24.1 0.1 2.3 1 1 0 1 1 1 1 SET domain AWS PF17907.1 RLN88064.1 - 0.68 10.0 10.5 2.1 8.4 10.5 1.9 1 0 0 1 1 1 0 AWS domain SWIM PF04434.17 RLN88065.1 - 0.0063 16.2 2.3 0.015 14.9 2.3 1.7 1 0 0 1 1 1 1 SWIM zinc finger DDE_Tnp_ISL3 PF01610.17 RLN88065.1 - 0.018 14.8 0.2 0.036 13.8 0.2 1.5 1 0 0 1 1 1 0 Transposase MULE PF10551.9 RLN88065.1 - 0.034 14.6 0.0 0.14 12.6 0.0 2.1 2 0 0 2 2 2 0 MULE transposase domain DUF5575 PF17738.1 RLN88065.1 - 0.039 13.0 1.0 0.57 9.2 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5575) Tubulin PF00091.25 RLN88066.1 - 7.6e-41 140.5 0.0 5.5e-40 137.7 0.0 2.0 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain zf-TAZ PF02135.16 RLN88068.1 - 0.05 14.1 31.7 0.043 14.3 8.0 2.8 3 0 0 3 3 3 0 TAZ zinc finger DUF3813 PF12758.7 RLN88068.1 - 0.055 13.8 1.0 0.18 12.2 1.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) MukF_M PF17192.4 RLN88068.1 - 0.5 10.1 5.9 2 8.1 0.2 2.5 2 1 0 2 2 2 0 MukF middle domain Defensin_beta_2 PF13841.6 RLN88068.1 - 4.1 8.0 6.0 13 6.4 6.0 1.8 1 0 0 1 1 1 0 Beta defensin Ras PF00071.22 RLN88069.1 - 9.3e-24 83.8 0.2 4.1e-13 49.3 0.2 2.3 1 1 1 2 2 2 2 Ras family Roc PF08477.13 RLN88069.1 - 4.2e-14 52.8 0.3 4.4e-12 46.3 0.2 2.5 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN88069.1 - 2.2e-07 30.5 0.3 2.2e-05 24.0 0.3 2.2 1 1 1 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RLN88069.1 - 0.0018 17.7 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 RLN88069.1 - 0.0039 17.6 0.1 0.012 16.0 0.0 1.7 1 1 1 2 2 2 1 AAA ATPase domain MCM PF00493.23 RLN88069.1 - 0.018 14.2 0.0 0.033 13.3 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain TniB PF05621.11 RLN88069.1 - 0.036 13.5 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 RLN88069.1 - 0.066 12.7 0.1 0.36 10.3 0.0 2.1 2 1 1 3 3 3 0 P-loop containing dynein motor region AAA_24 PF13479.6 RLN88069.1 - 0.094 12.4 0.1 0.15 11.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain Syntaxin_2 PF14523.6 RLN88070.1 - 3.7e-17 62.6 8.5 1.9e-16 60.2 3.6 2.2 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 RLN88070.1 - 0.00018 21.4 8.0 0.00062 19.7 8.0 2.1 1 1 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 RLN88070.1 - 0.0063 16.2 11.2 0.018 14.7 3.8 2.5 3 0 0 3 3 3 1 Syntaxin Synaptobrevin PF00957.21 RLN88070.1 - 0.0071 16.1 0.7 0.0071 16.1 0.7 2.3 2 1 1 3 3 3 1 Synaptobrevin TMCO5 PF14992.6 RLN88070.1 - 0.0081 15.8 2.1 1.6 8.3 0.6 2.1 2 0 0 2 2 2 2 TMCO5 family DUF948 PF06103.11 RLN88070.1 - 0.015 15.5 4.8 2.3 8.5 0.3 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.11 RLN88070.1 - 0.023 14.8 2.7 2.2 8.4 0.2 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HsbA PF12296.8 RLN88070.1 - 0.036 14.5 2.5 1.6 9.2 0.1 2.2 2 0 0 2 2 2 0 Hydrophobic surface binding protein A ING PF12998.7 RLN88070.1 - 0.039 14.6 2.1 1.4 9.5 0.3 2.5 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF4665 PF15679.5 RLN88070.1 - 0.062 13.9 4.6 0.93 10.1 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4665) TRIQK PF15168.6 RLN88070.1 - 0.08 12.8 0.7 0.37 10.7 0.2 2.3 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family TACC_C PF05010.14 RLN88070.1 - 0.14 11.9 5.8 0.46 10.2 0.1 2.6 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal LXG PF04740.12 RLN88070.1 - 0.17 11.5 4.6 2.3 7.9 0.8 2.4 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF1732 PF08340.11 RLN88070.1 - 0.22 11.5 3.3 0.16 11.9 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) WXG100 PF06013.12 RLN88070.1 - 0.24 11.6 4.5 1.8 8.9 0.1 3.0 3 1 0 3 3 3 0 Proteins of 100 residues with WXG CdvA PF18822.1 RLN88070.1 - 0.54 10.1 5.1 3.1 7.6 0.5 3.1 3 2 0 3 3 3 0 CdvA-like coiled-coil domain Spc7 PF08317.11 RLN88070.1 - 0.55 9.1 5.0 1.4 7.8 0.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Serine_rich PF08824.10 RLN88070.1 - 0.59 10.1 3.9 1.2 9.1 0.9 2.1 2 0 0 2 2 2 0 Serine rich protein interaction domain DUF3106 PF11304.8 RLN88070.1 - 0.68 10.4 3.6 0.53 10.8 1.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) Sec8_exocyst PF04048.14 RLN88070.1 - 0.76 9.7 4.6 2 8.3 0.3 3.1 2 2 1 3 3 3 0 Sec8 exocyst complex component specific domain Occludin_ELL PF07303.13 RLN88070.1 - 1 10.2 3.4 3.9 8.2 0.3 2.7 2 1 1 3 3 3 0 Occludin homology domain DUF5344 PF17279.2 RLN88070.1 - 1.2 9.8 4.7 21 5.8 0.3 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5344) DUF2570 PF10828.8 RLN88070.1 - 1.7 8.5 8.5 0.46 10.3 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2570) Seryl_tRNA_N PF02403.22 RLN88070.1 - 5.5 7.3 10.7 2.2 8.5 0.7 3.1 2 2 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain UQ_con PF00179.26 RLN88071.1 - 3.7e-50 169.2 0.0 4.2e-50 169.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RLN88071.1 - 0.0033 17.1 0.0 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 RLN88071.1 - 0.029 14.2 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 RLN88071.1 - 0.058 13.7 0.0 0.089 13.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain DUF4537 PF15057.6 RLN88073.1 - 2.7e-06 27.4 0.5 0.028 14.4 0.0 5.4 7 1 0 7 7 7 1 Domain of unknown function (DUF4537) DUF1325 PF07039.11 RLN88073.1 - 3.5e-05 23.9 0.1 0.18 11.9 0.0 3.3 2 0 0 2 2 2 2 SGF29 tudor-like domain 53-BP1_Tudor PF09038.10 RLN88073.1 - 0.00056 19.9 0.0 0.0028 17.6 0.0 2.2 2 0 0 2 2 2 1 Tumour suppressor p53-binding protein-1 Tudor Tudor_2 PF18104.1 RLN88073.1 - 0.0013 18.4 0.2 0.27 10.9 0.0 3.8 3 0 0 3 3 3 1 Jumonji domain-containing protein 2A Tudor domain LBR_tudor PF09465.10 RLN88073.1 - 0.0047 16.7 0.1 0.21 11.4 0.0 2.8 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain TUDOR_5 PF18359.1 RLN88073.1 - 0.012 15.3 0.8 0.048 13.4 0.8 2.1 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 VASt PF16016.5 RLN88073.1 - 0.071 13.5 0.4 4.5 7.7 0.0 2.6 2 0 0 2 2 2 0 VAD1 Analog of StAR-related lipid transfer domain Pns11_12 PF17464.2 RLN88073.1 - 0.26 11.0 1.7 0.74 9.5 1.7 1.7 1 0 0 1 1 1 0 Non-structural protein 11 and 12 DUF2737 PF10930.8 RLN88073.1 - 0.86 9.2 2.3 11 5.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2737) LAMTOR5 PF16672.5 RLN88074.1 - 1.1e-05 25.3 0.3 0.00025 20.9 0.3 2.1 1 1 0 1 1 1 1 Ragulator complex protein LAMTOR5 Tho2 PF11262.8 RLN88075.1 - 7.4 5.7 8.7 9.8 5.3 8.7 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 WD40 PF00400.32 RLN88076.1 - 0.038 14.9 0.2 2.1 9.4 0.1 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Arf PF00025.21 RLN88077.1 - 2.7e-113 375.4 0.6 5.9e-60 201.7 0.2 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 RLN88077.1 - 1.6e-18 66.8 0.2 1.4e-10 40.9 0.0 2.3 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit Roc PF08477.13 RLN88077.1 - 1.7e-17 63.8 1.0 1.1e-09 38.5 0.4 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RLN88077.1 - 3.2e-14 52.9 0.1 3.5e-07 29.9 0.1 2.1 2 0 0 2 2 2 2 Ras family G-alpha PF00503.20 RLN88077.1 - 9e-13 48.1 6.7 1.4e-08 34.3 0.4 3.4 2 2 1 3 3 3 2 G-protein alpha subunit Gtr1_RagA PF04670.12 RLN88077.1 - 7.3e-11 41.9 0.1 1.5e-05 24.5 0.0 2.1 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RLN88077.1 - 1.6e-10 41.0 0.2 5.7e-05 23.2 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RLN88077.1 - 3.1e-06 26.8 3.9 0.087 12.4 0.0 3.6 2 1 1 4 4 4 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 RLN88077.1 - 0.00066 20.2 1.7 0.26 11.8 0.1 2.9 2 2 0 2 2 2 2 ABC transporter NOG1 PF06858.14 RLN88077.1 - 0.0016 18.2 1.7 0.15 11.9 0.1 3.1 3 1 0 3 3 3 1 Nucleolar GTP-binding protein 1 (NOG1) AAA_24 PF13479.6 RLN88077.1 - 0.0038 17.0 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF2325 PF10087.9 RLN88077.1 - 0.0041 17.2 0.1 0.047 13.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2325) 6PF2K PF01591.18 RLN88077.1 - 0.015 14.7 0.3 4.6 6.5 0.0 2.4 2 1 0 2 2 2 0 6-phosphofructo-2-kinase AAA_18 PF13238.6 RLN88077.1 - 0.066 13.8 0.5 14 6.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 RLN88077.1 - 0.076 12.9 0.4 13 5.7 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 RLN88077.1 - 0.13 12.3 0.8 20 5.2 0.1 2.6 2 1 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 RLN88077.1 - 0.19 10.5 0.5 2.1 7.0 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_22 PF13401.6 RLN88077.1 - 1.4 9.2 6.5 2.6 8.3 0.5 3.6 2 2 0 2 2 2 0 AAA domain Arf PF00025.21 RLN88078.1 - 8.3e-64 214.2 0.1 9.4e-64 214.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RLN88078.1 - 5e-15 55.8 0.3 6.9e-15 55.3 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RLN88078.1 - 1.4e-12 47.5 0.2 1.6e-12 47.3 0.2 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 RLN88078.1 - 2.3e-12 46.7 0.1 2.8e-12 46.4 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RLN88078.1 - 2.3e-10 40.2 1.1 2e-07 30.5 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 RLN88078.1 - 1.4e-06 27.8 0.0 1.8e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RLN88078.1 - 4e-06 26.9 0.1 7.4e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RLN88078.1 - 0.00023 20.8 0.3 0.0033 17.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain NOG1 PF06858.14 RLN88078.1 - 0.0094 15.7 0.1 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) ABC_tran PF00005.27 RLN88078.1 - 0.013 16.0 0.2 0.036 14.6 0.2 1.6 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 RLN88078.1 - 0.07 13.2 0.2 0.11 12.5 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RLN88078.1 - 0.082 13.1 0.1 2.3 8.4 0.0 2.2 1 1 0 2 2 2 0 AAA domain SBD_N PF07005.11 RLN88078.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Sugar-binding N-terminal domain PduV-EutP PF10662.9 RLN88078.1 - 0.14 11.9 0.3 0.49 10.1 0.3 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PGM_PMM_I PF02878.16 RLN88079.1 - 2.3e-34 118.1 0.0 4.7e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 RLN88079.1 - 1.5e-22 80.1 0.0 4.8e-22 78.5 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 RLN88079.1 - 5.5e-15 55.6 0.1 1.1e-14 54.7 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 RLN88079.1 - 5.5e-07 29.7 0.0 1.7e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Ribosomal_S13_N PF08069.12 RLN88080.1 - 2.6e-33 113.9 0.7 2.9e-33 113.7 0.7 1.0 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain zf-C2H2 PF00096.26 RLN88082.1 - 1.4e-16 59.9 28.6 9.1e-05 22.7 2.0 4.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RLN88082.1 - 1.9e-15 56.5 29.7 7.4e-06 26.2 1.1 5.3 5 0 0 5 5 5 4 Zinc-finger double domain BET PF17035.5 RLN88082.1 - 7.7e-11 42.0 0.0 1.6e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation zf-C2H2_4 PF13894.6 RLN88082.1 - 2.7e-09 37.1 26.0 0.003 18.3 1.4 4.7 5 0 0 5 5 4 4 C2H2-type zinc finger zf-TRAF PF02176.18 RLN88082.1 - 0.00015 22.4 9.7 0.011 16.5 2.5 2.3 1 1 1 2 2 2 2 TRAF-type zinc finger zf-C2H2_jaz PF12171.8 RLN88082.1 - 0.00018 21.7 0.5 0.00018 21.7 0.5 4.4 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 RLN88082.1 - 0.14 12.8 0.3 0.14 12.8 0.3 3.7 2 1 2 4 4 4 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 RLN88082.1 - 0.65 10.1 9.6 0.61 10.2 3.0 2.8 2 1 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_9 PF16293.5 RLN88082.1 - 1.2 9.0 3.7 2.7 7.9 0.1 2.7 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 RLN88082.1 - 1.3 9.0 6.6 0.82 9.6 1.0 2.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 RLN88082.1 - 1.5 9.2 12.5 10 6.5 0.7 3.4 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-met PF12874.7 RLN88082.1 - 3.2 8.3 18.0 0.18 12.3 0.7 4.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 RLN88082.1 - 6.2 7.2 13.5 3.3 8.1 2.0 2.8 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Mannosyl_trans3 PF11051.8 RLN88083.1 - 0.0023 17.4 0.0 0.0031 16.9 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative Peptidase_S8 PF00082.22 RLN88084.1 - 7.8e-43 146.8 5.5 1.1e-42 146.3 5.5 1.3 1 0 0 1 1 1 1 Subtilase family Exonuc_VIII PF06630.11 RLN88084.1 - 0.11 12.3 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 Enterobacterial exodeoxyribonuclease VIII Elicitin PF00964.17 RLN88085.1 - 1.7e-19 69.7 0.6 2.4e-19 69.2 0.6 1.3 1 0 0 1 1 1 1 Elicitin PT PF04886.12 RLN88085.1 - 0.014 15.0 27.9 0.014 15.0 27.9 1.9 2 0 0 2 2 2 0 PT repeat REJ PF02010.15 RLN88087.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 REJ domain DUF5600 PF18150.1 RLN88088.1 - 3e-12 47.1 0.0 3.7e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) S1 PF00575.23 RLN88089.1 - 1.3e-29 102.3 22.2 6.5e-08 32.8 0.1 9.0 8 2 0 8 8 8 6 S1 RNA binding domain PCB_OB PF17092.5 RLN88089.1 - 0.18 12.6 10.6 15 6.4 0.0 6.3 5 2 0 6 6 6 0 Penicillin-binding protein OB-like domain ATG11 PF10377.9 RLN88090.1 - 3.7e-20 72.3 0.0 4.7e-19 68.7 0.0 2.7 2 1 0 3 3 3 1 Autophagy-related protein 11 TSC22 PF01166.18 RLN88090.1 - 0.049 14.0 2.2 0.62 10.4 1.9 3.0 3 0 0 3 3 3 0 TSC-22/dip/bun family BORCS6 PF10157.9 RLN88090.1 - 0.065 13.4 1.3 0.18 12.0 0.6 2.2 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 6 NBP1 PF08537.10 RLN88090.1 - 0.084 12.3 0.2 0.084 12.3 0.2 2.2 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 PPE PF00823.19 RLN88090.1 - 0.75 9.9 4.1 5.4 7.1 0.5 2.6 2 0 0 2 2 2 0 PPE family Atg14 PF10186.9 RLN88090.1 - 1.4 7.9 12.6 3.7 6.5 0.1 3.5 3 1 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sec8_exocyst PF04048.14 RLN88090.1 - 2.2 8.2 10.6 0.22 11.4 0.4 3.7 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain Bacillus_HBL PF05791.11 RLN88090.1 - 4.4 7.1 8.7 33 4.3 0.0 4.1 5 0 0 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) PI3K_P85_iSH2 PF16454.5 RLN88090.1 - 5.9 6.5 23.6 0.082 12.5 0.7 4.1 2 2 2 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain BTB PF00651.31 RLN88091.1 - 4.3e-12 46.3 1.2 7.4e-12 45.5 0.6 1.8 2 0 0 2 2 2 1 BTB/POZ domain Cnd1 PF12717.7 RLN88091.1 - 4.6e-07 30.0 0.1 1.1e-05 25.5 0.1 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RLN88091.1 - 9.1e-05 22.4 2.6 0.87 10.0 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat Arm_2 PF04826.13 RLN88091.1 - 0.00066 19.2 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Armadillo-like HEAT_2 PF13646.6 RLN88091.1 - 0.00079 19.8 0.2 0.02 15.3 0.0 2.8 2 1 1 3 3 3 1 HEAT repeats Arm PF00514.23 RLN88091.1 - 0.0013 18.7 2.5 0.028 14.5 0.0 4.1 4 1 1 5 5 5 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 RLN88091.1 - 0.057 13.6 0.2 0.37 11.0 0.0 2.4 2 2 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Phage_DsbA PF11126.8 RLN88091.1 - 0.095 12.9 0.2 0.2 11.9 0.2 1.5 1 0 0 1 1 1 0 Transcriptional regulator DsbA NAD_binding_10 PF13460.6 RLN88092.1 - 1.1e-07 32.0 0.0 2.3e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 RLN88092.1 - 1.6e-05 24.5 0.0 3.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RLN88092.1 - 0.0011 18.5 0.0 0.0022 17.4 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 RLN88092.1 - 0.2 10.7 0.0 0.45 9.5 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Na_H_Exchanger PF00999.21 RLN88093.1 - 1.7e-54 185.1 30.7 3.9e-54 183.9 30.7 1.5 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family BRI3BP PF14965.6 RLN88093.1 - 0.3 10.6 5.5 0.11 12.1 0.4 2.4 2 0 0 2 2 2 0 Negative regulator of p53/TP53 PH PF00169.29 RLN88094.1 - 1.1e-05 25.8 0.0 2.8e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF3318 PF11780.8 RLN88095.1 - 0.19 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) ArfGap PF01412.18 RLN88096.1 - 2.4e-31 108.2 2.2 6.8e-31 106.8 2.2 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf uDENN PF03456.18 RLN88096.1 - 5.1e-12 46.4 0.4 1.7e-11 44.7 0.4 2.0 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 RLN88096.1 - 6.6e-11 42.0 4.6 6.6e-11 42.0 4.6 2.3 2 0 0 2 2 2 1 dDENN domain Ribosomal_L27e PF01777.18 RLN88097.1 - 9.2e-30 102.8 3.0 2e-29 101.8 3.0 1.6 1 1 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 RLN88097.1 - 0.00014 21.7 0.4 0.00051 19.9 0.4 2.0 1 0 0 1 1 1 1 KOW motif Longin PF13774.6 RLN88098.1 - 4e-08 33.2 0.0 6.5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain ABC_tran PF00005.27 RLN88099.1 - 1e-07 32.5 0.1 1.7e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 RLN88099.1 - 0.00046 20.6 0.0 0.00089 19.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RLN88099.1 - 0.0016 18.7 0.1 0.0037 17.6 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.6 RLN88099.1 - 0.007 16.1 1.2 0.0098 15.6 0.2 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 RLN88099.1 - 0.007 15.7 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 RLN88099.1 - 0.011 15.7 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase DUF815 PF05673.13 RLN88099.1 - 0.02 14.0 0.0 0.027 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 RLN88099.1 - 0.027 14.5 0.1 0.067 13.3 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 RLN88099.1 - 0.031 14.2 0.1 0.077 12.9 0.0 1.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_18 PF13238.6 RLN88099.1 - 0.065 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 RLN88099.1 - 0.067 13.3 0.2 0.14 12.2 0.1 1.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_5 PF07728.14 RLN88099.1 - 0.071 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 RLN88099.1 - 0.077 12.3 1.1 0.72 9.2 0.2 2.3 2 1 1 3 3 3 0 KaiC AAA_25 PF13481.6 RLN88099.1 - 0.089 12.4 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain VirE PF05272.11 RLN88099.1 - 0.091 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E RNA_helicase PF00910.22 RLN88099.1 - 0.14 12.5 0.1 0.5 10.8 0.0 1.9 2 1 0 2 2 2 0 RNA helicase Radial_spoke_3 PF06098.11 RLN88100.1 - 1.2e-41 142.9 4.1 1.6e-41 142.5 4.1 1.1 1 0 0 1 1 1 1 Radial spoke protein 3 LBR_tudor PF09465.10 RLN88101.1 - 0.00027 20.7 0.1 0.00046 19.9 0.1 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Tudor_3 PF18115.1 RLN88101.1 - 0.027 14.3 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain Lsm_C PF14894.6 RLN88101.1 - 0.032 14.0 0.3 0.062 13.1 0.3 1.4 1 0 0 1 1 1 0 Lsm C-terminal DUF4537 PF15057.6 RLN88101.1 - 0.037 14.1 0.1 0.064 13.3 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4537) Voltage_CLC PF00654.20 RLN88102.1 - 2e-57 195.0 29.9 2e-57 195.0 29.9 1.5 1 1 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 RLN88102.1 - 5e-05 23.7 0.4 0.16 12.4 0.1 2.5 2 0 0 2 2 2 2 CBS domain Complex1_LYR_2 PF13233.6 RLN88104.1 - 4.6e-16 59.3 1.9 7.5e-16 58.7 1.9 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 RLN88104.1 - 1.3e-06 28.4 0.4 2.4e-06 27.5 0.4 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Voltage_CLC PF00654.20 RLN88105.1 - 1.5e-54 185.6 31.4 1.9e-54 185.3 31.4 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel YfzA PF14118.6 RLN88105.1 - 0.086 13.3 1.0 4.7 7.7 0.2 3.0 1 1 1 2 2 2 0 YfzA-like protein PDZ_6 PF17820.1 RLN88106.1 - 0.0027 17.5 0.0 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RLN88106.1 - 0.026 14.9 0.0 0.057 13.8 0.0 1.7 1 1 0 1 1 1 0 PDZ domain TMEM51 PF15345.6 RLN88106.1 - 0.85 9.4 5.5 1.2 9.0 5.5 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF2722 PF10846.8 RLN88106.1 - 0.89 8.4 12.6 1.1 8.1 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TIMELESS PF04821.14 RLN88107.1 - 8.7e-56 189.2 4.5 8.7e-56 189.2 4.5 2.0 2 0 0 2 2 2 1 Timeless protein SLIDE PF09111.10 RLN88107.1 - 0.065 13.3 0.3 0.73 9.9 0.2 2.6 2 0 0 2 2 2 0 SLIDE DENN PF02141.21 RLN88108.1 - 6.7e-29 101.2 1.8 1.5e-28 100.0 1.8 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain RGS PF00615.19 RLN88108.1 - 1.6e-14 54.1 10.5 1.1e-06 29.0 2.4 3.0 2 1 0 2 2 2 2 Regulator of G protein signaling domain dDENN PF03455.19 RLN88108.1 - 0.0005 20.0 0.2 0.0024 17.8 0.1 2.3 2 0 0 2 2 2 1 dDENN domain GMC_oxred_N PF00732.19 RLN88109.1 - 7.2e-101 337.5 0.0 1.1e-100 336.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 RLN88109.1 - 1.4e-39 135.9 0.0 2.5e-39 135.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 RLN88109.1 - 1.3e-08 34.4 0.0 0.0033 16.6 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 RLN88109.1 - 4.4e-06 26.0 0.1 6.5e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 RLN88109.1 - 1.4e-05 24.5 0.0 0.0002 20.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RLN88109.1 - 3.7e-05 23.5 0.2 0.00047 19.9 0.2 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RLN88109.1 - 0.00033 20.8 0.1 0.0011 19.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 RLN88109.1 - 0.00075 19.0 0.4 1.1 8.5 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 RLN88109.1 - 0.00096 19.7 0.0 0.029 14.9 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 RLN88109.1 - 0.0079 15.8 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 RLN88109.1 - 0.015 14.1 0.0 0.054 12.2 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 RLN88109.1 - 0.017 14.4 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 RLN88109.1 - 0.018 15.3 0.0 0.067 13.5 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.17 RLN88109.1 - 0.025 13.8 0.2 0.079 12.2 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Abhydrolase_6 PF12697.7 RLN88109.1 - 0.05 14.2 0.2 0.096 13.3 0.2 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family FAD_binding_3 PF01494.19 RLN88109.1 - 0.1 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 RLN88109.1 - 0.2 10.7 0.0 1.4 7.9 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A PLAC8 PF04749.17 RLN88110.1 - 1.3e-19 71.1 15.5 5e-19 69.1 15.5 1.8 1 1 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 RLN88111.1 - 1.3e-18 67.8 22.8 7e-18 65.5 22.8 1.9 1 1 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 RLN88112.1 - 8.1e-46 155.1 69.7 2.6e-18 66.8 18.5 4.3 4 0 0 4 4 4 4 PLAC8 family Pkinase PF00069.25 RLN88113.1 - 4.4e-38 131.2 0.0 5.7e-37 127.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN88113.1 - 4.7e-14 52.3 0.3 2.1e-06 27.2 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RLN88113.1 - 0.0016 17.9 0.1 0.003 16.9 0.0 1.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 RLN88113.1 - 0.0061 16.5 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN88113.1 - 0.015 14.7 0.1 0.021 14.1 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 RLN88113.1 - 0.055 12.5 0.2 0.083 11.9 0.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 RLN88113.1 - 0.061 12.3 0.0 0.085 11.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_C PF00433.24 RLN88113.1 - 0.062 14.0 0.6 0.19 12.5 0.6 1.9 1 1 0 1 1 1 0 Protein kinase C terminal domain Tricorn_C1 PF14684.6 RLN88113.1 - 0.23 11.6 0.1 9 6.4 0.0 2.8 3 0 0 3 3 3 0 Tricorn protease C1 domain PLAC8 PF04749.17 RLN88114.1 - 2.9e-33 114.8 34.3 5.9e-16 59.3 15.2 3.3 2 2 0 2 2 2 2 PLAC8 family Stevor PF17410.2 RLN88114.1 - 0.0026 17.3 0.2 2.5 7.6 0.1 2.8 3 0 0 3 3 3 2 Subtelomeric Variable Open Reading frame Virul_fac_BrkB PF03631.15 RLN88114.1 - 0.021 14.4 6.0 0.03 13.9 2.3 2.1 2 0 0 2 2 2 0 Virulence factor BrkB DUF3671 PF12420.8 RLN88114.1 - 0.24 11.5 0.1 4 7.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF4006 PF13179.6 RLN88114.1 - 4.1 7.4 5.0 0.56 10.2 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF4006) MULE PF10551.9 RLN88115.1 - 0.00029 21.2 0.6 0.0032 17.9 0.0 2.5 2 0 0 2 2 2 1 MULE transposase domain Pkinase_Tyr PF07714.17 RLN88117.1 - 3.7e-65 219.8 0.0 1.2e-40 139.4 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN88117.1 - 2.5e-58 197.5 0.0 1.8e-36 125.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 RLN88117.1 - 1e-08 34.9 0.0 0.0019 17.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 RLN88117.1 - 0.00013 21.4 0.2 0.1 11.9 0.0 3.2 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Actin PF00022.19 RLN88118.1 - 9.4e-46 156.2 0.0 1e-45 156.1 0.0 1.0 1 0 0 1 1 1 1 Actin SF3A2 PF16835.5 RLN88119.1 - 2e-37 127.4 0.0 3.3e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) ubiquitin PF00240.23 RLN88119.1 - 7.6e-08 32.0 0.0 1.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family zf-met PF12874.7 RLN88119.1 - 6e-07 29.7 1.3 1.4e-06 28.4 1.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 RLN88119.1 - 6e-05 23.0 0.1 9.7e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Ubiquitin_2 PF14560.6 RLN88119.1 - 0.0026 18.2 0.0 0.013 16.0 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain Peptidase_C54 PF03416.19 RLN88120.1 - 6.7e-90 301.2 0.0 8e-90 301.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 RLN88120.1 - 0.035 13.6 0.1 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 Peptidase family C78 FA_desaturase PF00487.24 RLN88121.1 - 4.5e-24 85.7 7.5 5.7e-24 85.3 7.5 1.1 1 0 0 1 1 1 1 Fatty acid desaturase RNA_pol_Rpb2_3 PF04565.16 RLN88121.1 - 0.096 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 3 Thaumatin PF00314.17 RLN88122.1 - 5.7e-05 22.9 2.0 0.0045 16.7 1.6 2.9 1 1 1 2 2 2 2 Thaumatin family CcmD PF04995.14 RLN88122.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF4366 PF14283.6 RLN88122.1 - 0.87 9.6 9.9 0.056 13.5 1.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) TPR_1 PF00515.28 RLN88123.1 - 1.6e-21 75.1 0.0 2.6e-06 27.0 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN88123.1 - 2.3e-18 64.8 0.1 2.7e-05 23.9 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN88123.1 - 1.6e-12 46.9 0.3 0.00021 20.9 0.1 3.3 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 RLN88123.1 - 2.2e-10 39.9 0.0 0.0026 17.9 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 RLN88123.1 - 2.4e-08 34.1 0.4 0.027 15.3 0.6 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 RLN88123.1 - 1.3e-07 31.8 1.2 0.00016 21.9 0.6 3.1 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN88123.1 - 8.5e-07 29.5 0.7 0.0022 18.6 0.3 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN88123.1 - 1.1e-05 25.4 2.5 0.036 14.4 0.0 4.1 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN88123.1 - 4.7e-05 23.4 2.7 0.0052 16.9 1.1 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN88123.1 - 0.00015 22.2 0.8 0.013 16.0 0.7 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN88123.1 - 0.00054 20.4 0.6 0.11 13.2 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN88123.1 - 0.00089 19.1 5.6 5.2 7.3 0.0 4.0 5 0 0 5 5 4 2 Tetratricopeptide repeat DUF3856 PF12968.7 RLN88123.1 - 0.0037 17.3 0.1 2.1 8.4 0.0 2.4 1 1 1 2 2 2 2 Domain of Unknown Function (DUF3856) TPR_15 PF13429.6 RLN88123.1 - 0.0091 15.2 0.1 0.92 8.7 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 RLN88123.1 - 0.025 15.0 0.4 0.025 15.0 0.4 1.8 2 0 0 2 2 2 0 Bacterial transcriptional activator domain baeRF_family3 PF18845.1 RLN88123.1 - 0.03 14.6 1.9 0.072 13.4 0.0 2.3 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 3 ANAPC3 PF12895.7 RLN88123.1 - 0.18 12.1 1.3 1 9.6 1.2 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PCRF PF03462.18 RLN88123.1 - 0.71 9.7 6.0 2.5 7.9 0.3 2.1 2 0 0 2 2 2 0 PCRF domain WD40 PF00400.32 RLN88124.1 - 6e-43 144.0 9.1 1.1e-07 32.4 0.3 8.1 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN88124.1 - 1.9e-18 66.6 0.0 0.001 19.3 0.0 5.9 4 1 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN88124.1 - 1.5e-11 43.7 5.4 0.0047 15.6 0.0 4.3 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RLN88124.1 - 1.7e-07 30.6 0.3 0.54 9.2 0.0 5.0 3 1 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 RLN88124.1 - 1.3e-06 28.4 0.0 0.00053 19.9 0.0 3.8 4 1 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 RLN88124.1 - 0.0023 16.8 0.0 0.6 8.8 0.0 2.9 2 1 0 3 3 3 2 Nup133 N terminal like WD40_like PF17005.5 RLN88124.1 - 0.0041 16.5 0.0 0.012 15.0 0.0 1.7 2 0 0 2 2 2 1 WD40-like domain Cytochrom_D1 PF02239.16 RLN88124.1 - 0.0053 15.3 0.0 0.068 11.7 0.0 2.4 2 1 1 3 3 3 1 Cytochrome D1 heme domain Frtz PF11768.8 RLN88124.1 - 0.0072 14.7 0.0 0.049 11.9 0.0 2.1 3 0 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Proteasome_A_N PF10584.9 RLN88124.1 - 0.073 12.8 1.3 2 8.2 0.1 2.9 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Cystatin PF00031.21 RLN88125.1 - 0.0021 18.3 0.0 0.022 15.0 0.0 2.2 2 0 0 2 2 2 1 Cystatin domain Trp_oprn_chp PF09534.10 RLN88125.1 - 0.033 14.0 8.2 0.085 12.6 0.2 2.5 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SQAPI PF16845.5 RLN88125.1 - 0.19 12.1 2.0 0.37 11.1 0.1 2.4 3 0 0 3 3 3 0 Aspartic acid proteinase inhibitor IQ PF00612.27 RLN88126.1 - 2.5e-05 23.7 0.1 6e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Med29 PF11568.8 RLN88126.1 - 0.064 13.5 10.2 0.059 13.6 4.4 2.8 1 1 1 2 2 2 0 Mediator complex subunit 29 BLOC1_2 PF10046.9 RLN88126.1 - 0.17 12.2 22.5 0.64 10.4 9.9 3.3 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.11 RLN88126.1 - 0.24 11.8 13.0 0.54 10.7 0.6 4.3 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 RLN88126.1 - 0.33 11.0 10.0 14 5.7 6.4 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TEX12 PF15219.6 RLN88126.1 - 0.38 11.1 6.4 0.14 12.5 1.7 2.6 2 1 0 2 2 2 0 Testis-expressed 12 Viral_P18 PF04521.13 RLN88126.1 - 0.54 10.0 7.3 0.2 11.5 0.7 2.4 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein ApoO PF09769.9 RLN88126.1 - 2.7 7.9 4.7 6 6.8 1.0 2.5 2 0 0 2 2 2 0 Apolipoprotein O Trp_oprn_chp PF09534.10 RLN88128.1 - 0.0067 16.2 0.1 0.14 11.9 0.1 2.1 2 0 0 2 2 2 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Myosin_head PF00063.21 RLN88129.1 - 4.6e-52 177.2 0.0 7.1e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Ank_2 PF12796.7 RLN88129.1 - 7.8e-38 128.9 9.7 2.1e-13 50.6 0.1 5.1 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 RLN88129.1 - 9.9e-32 108.0 9.2 0.00034 20.9 0.1 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 RLN88129.1 - 2.2e-28 98.3 6.4 1.3e-07 32.0 0.1 7.3 3 3 4 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN88129.1 - 1.7e-27 95.1 10.4 1.6e-10 41.0 0.2 6.8 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN88129.1 - 5e-26 87.9 2.8 0.0079 16.6 0.0 8.5 8 0 0 8 8 8 6 Ankyrin repeat FYVE PF01363.21 RLN88129.1 - 3.5e-16 59.1 14.4 3.5e-16 59.1 14.4 1.8 2 0 0 2 2 2 1 FYVE zinc finger IQ PF00612.27 RLN88129.1 - 0.00012 21.6 12.0 0.018 14.8 0.1 3.5 4 0 0 4 4 4 2 IQ calmodulin-binding motif WD40 PF00400.32 RLN88130.1 - 2.7e-43 145.1 14.8 2.7e-08 34.4 0.1 12.3 13 0 0 13 13 13 7 WD domain, G-beta repeat Utp12 PF04003.12 RLN88130.1 - 3.6e-23 81.9 0.4 7.1e-23 81.0 0.4 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 RLN88130.1 - 1.8e-20 73.1 0.0 0.0053 17.0 0.0 8.9 3 2 6 10 10 10 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN88130.1 - 1.1e-07 31.1 0.1 0.29 10.0 0.1 4.7 3 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RLN88130.1 - 2.8e-06 26.3 0.0 0.016 13.9 0.0 3.3 1 1 3 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.11 RLN88130.1 - 3.3e-05 23.9 0.0 2.3 8.1 0.0 4.3 3 1 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 RLN88130.1 - 0.00012 20.7 0.4 0.54 8.7 0.1 3.5 3 1 0 3 3 3 2 Cytochrome D1 heme domain Proteasome_A_N PF10584.9 RLN88130.1 - 0.0011 18.7 0.6 0.66 9.7 0.0 4.3 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature PD40 PF07676.12 RLN88130.1 - 0.0024 17.7 2.0 32 4.6 0.0 6.2 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 RLN88130.1 - 0.0039 16.6 0.1 1.8 7.9 0.0 3.8 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.9 RLN88130.1 - 0.022 14.5 2.5 4.4 7.0 0.0 4.4 4 1 1 5 5 5 0 Lipoprotein LpqB beta-propeller domain Utp21 PF04192.12 RLN88130.1 - 0.023 14.2 2.2 0.13 11.8 0.1 2.6 3 0 0 3 3 3 0 Utp21 specific WD40 associated putative domain RNA_pol_Rpc34 PF05158.12 RLN88131.1 - 3.5e-55 187.7 0.1 2.2e-38 132.5 0.0 3.8 1 1 2 3 3 3 3 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 RLN88131.1 - 0.023 14.8 0.2 0.06 13.5 0.2 1.7 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC HxlR PF01638.17 RLN88131.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 HxlR-like helix-turn-helix zf-C2H2 PF00096.26 RLN88132.1 - 2.6e-13 49.6 57.9 0.00035 20.9 1.2 7.5 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN88132.1 - 1.7e-07 31.5 54.8 0.061 14.2 1.0 7.5 7 0 0 7 7 7 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RLN88132.1 - 2.3e-07 31.0 10.4 2.8e-05 24.3 2.1 7.4 9 0 0 9 9 9 3 Zinc-finger double domain SlyX PF04102.12 RLN88132.1 - 0.0043 17.7 0.6 0.015 15.9 0.0 2.1 2 0 0 2 2 2 1 SlyX Mis14 PF08641.12 RLN88132.1 - 0.15 12.4 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Kinetochore protein Mis14 like zf-C2H2_6 PF13912.6 RLN88132.1 - 0.16 12.0 36.9 0.088 12.8 2.3 5.6 6 0 0 6 6 6 0 C2H2-type zinc finger FOXP-CC PF16159.5 RLN88132.1 - 0.32 11.7 8.6 1.5 9.5 0.6 3.7 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-met PF12874.7 RLN88132.1 - 0.45 11.0 27.2 2.3 8.7 0.4 6.6 7 0 0 7 7 7 0 Zinc-finger of C2H2 type CpXC PF14353.6 RLN88132.1 - 0.75 9.9 8.6 3.8 7.6 0.1 4.0 3 1 1 4 4 4 0 CpXC protein zinc_ribbon_4 PF13717.6 RLN88132.1 - 1.4 8.9 0.0 1.4 8.9 0.0 4.4 5 0 0 5 5 5 0 zinc-ribbon domain BolA PF01722.18 RLN88132.1 - 2.6 8.4 7.2 3.6 7.9 2.0 2.6 2 0 0 2 2 2 0 BolA-like protein zf-C2H2_aberr PF17017.5 RLN88132.1 - 5.3 7.1 10.1 8.7 6.5 0.1 3.6 3 1 0 4 4 4 0 Aberrant zinc-finger CytochromB561_N PF09786.9 RLN88133.1 - 2e-15 56.8 0.1 2.8e-15 56.3 0.1 1.2 1 0 0 1 1 1 1 Cytochrome B561, N terminal Casc1 PF12366.8 RLN88133.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 Exo_endo_phos PF03372.23 RLN88134.1 - 5.5e-14 52.3 0.0 1.2e-13 51.1 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Laminin_B PF00052.18 RLN88135.1 - 1.4e-12 47.7 0.0 6.7e-12 45.5 0.0 1.9 1 1 0 1 1 1 1 Laminin B (Domain IV) Sel1 PF08238.12 RLN88136.1 - 2.3e-24 85.3 16.2 1.1e-05 25.9 0.6 8.4 8 0 0 8 8 8 7 Sel1 repeat SLAIN PF15301.6 RLN88136.1 - 0.015 14.6 0.4 0.023 14.0 0.4 1.2 1 0 0 1 1 1 0 SLAIN motif-containing family NAM-associated PF14303.6 RLN88136.1 - 0.018 15.8 4.2 0.031 15.0 4.2 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain TPR_11 PF13414.6 RLN88136.1 - 0.19 11.5 5.3 1.9 8.2 0.3 4.0 4 0 0 4 4 4 0 TPR repeat TPR_1 PF00515.28 RLN88136.1 - 0.5 10.3 13.2 37 4.4 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat EGF_2 PF07974.13 RLN88137.1 - 4.3e-11 43.0 77.5 0.00048 20.4 2.7 7.7 6 1 1 7 7 7 6 EGF-like domain EGF PF00008.27 RLN88137.1 - 0.0031 17.8 14.3 0.0031 17.8 14.3 8.0 8 0 0 8 8 8 5 EGF-like domain RabGAP-TBC PF00566.18 RLN88138.1 - 1.1e-33 116.7 0.0 1.5e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PMC2NT PF08066.12 RLN88138.1 - 0.18 12.5 0.0 0.45 11.2 0.0 1.6 1 0 0 1 1 1 0 PMC2NT (NUC016) domain E1-E2_ATPase PF00122.20 RLN88139.1 - 2.6e-14 53.2 0.1 4e-14 52.5 0.1 1.2 1 0 0 1 1 1 1 E1-E2 ATPase PhoLip_ATPase_N PF16209.5 RLN88139.1 - 1.1e-09 37.9 0.0 3.2e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal HisKA_7TM PF16927.5 RLN88139.1 - 0.01 15.9 2.9 0.017 15.2 2.9 1.3 1 0 0 1 1 1 1 N-terminal 7TM region of histidine kinase Metallophos PF00149.28 RLN88140.1 - 2.3e-25 90.3 0.0 9.3e-25 88.3 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase CAP_GLY PF01302.25 RLN88140.1 - 1.4e-12 47.4 0.0 1.2e-11 44.5 0.0 2.4 2 0 0 2 2 2 1 CAP-Gly domain PPP5 PF08321.12 RLN88140.1 - 2e-05 24.8 0.0 4.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 PPP5 TPR repeat region zf-CCHC PF00098.23 RLN88141.1 - 4e-06 26.6 1.4 4e-06 26.6 1.4 1.8 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.17 RLN88141.1 - 5.3e-05 23.4 0.1 5.3e-05 23.4 0.1 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 RLN88141.1 - 6.9e-05 22.6 2.6 0.00012 21.8 2.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 RLN88141.1 - 0.1 12.3 0.3 0.2 11.4 0.3 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger PfkB PF00294.24 RLN88145.1 - 2.1e-54 184.9 0.7 2.1e-54 184.9 0.7 2.3 3 0 0 3 3 3 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 RLN88145.1 - 9.6e-09 35.0 0.1 3.5e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Yop-YscD_cpl PF16697.5 RLN88145.1 - 0.0012 19.1 0.0 0.0037 17.5 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Carb_kinase PF01256.17 RLN88145.1 - 0.015 14.8 0.0 0.041 13.3 0.0 1.8 1 0 0 1 1 1 0 Carbohydrate kinase FHA PF00498.26 RLN88145.1 - 0.046 14.1 0.0 0.087 13.2 0.0 1.5 1 0 0 1 1 1 0 FHA domain MRP-S26 PF14943.6 RLN88145.1 - 1.6 8.6 5.7 2.7 7.9 5.7 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Guanylate_cyc PF00211.20 RLN88146.1 - 4.6e-15 55.7 0.0 7.4e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF1996 PF09362.10 RLN88147.1 - 3.7e-74 249.7 0.3 5.1e-74 249.2 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) ADH_zinc_N PF00107.26 RLN88147.1 - 3.5e-20 72.3 0.0 6.1e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN88147.1 - 5.2e-14 53.4 0.0 9.9e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Phos_pyr_kin PF08543.12 RLN88148.1 - 1.7e-82 276.5 2.7 1e-81 273.9 2.7 1.9 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 RLN88148.1 - 1.8e-06 27.5 0.2 2.7e-05 23.7 0.2 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.15 RLN88148.1 - 5.9e-05 22.6 1.9 0.0065 15.9 0.1 2.6 3 0 0 3 3 3 2 Hydroxyethylthiazole kinase family TENA_THI-4 PF03070.16 RLN88149.1 - 8.5e-27 94.3 0.0 1.1e-26 94.0 0.0 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Haem_oxygenas_2 PF14518.6 RLN88149.1 - 0.084 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Iron-containing redox enzyme RPN6_N PF18055.1 RLN88149.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain Pectate_lyase PF03211.13 RLN88151.1 - 3.5e-22 78.9 0.3 3.8e-20 72.3 0.0 2.1 1 1 1 2 2 2 2 Pectate lyase FPN1 PF06963.12 RLN88152.1 - 2.7e-88 296.4 14.1 3.1e-88 296.2 14.1 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) MFS_1 PF07690.16 RLN88152.1 - 0.017 14.1 29.3 0.0086 15.0 9.1 3.1 2 1 1 3 3 3 0 Major Facilitator Superfamily OGG_N PF07934.12 RLN88153.1 - 9.6e-19 67.6 0.0 1.8e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 RLN88153.1 - 1.1e-10 41.9 0.0 2e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Myotub-related PF06602.14 RLN88154.1 - 8e-116 386.8 0.0 1.1e-115 386.4 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain CAP PF00188.26 RLN88154.1 - 8.3e-16 59.0 0.3 1.7e-15 58.0 0.3 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Y_phosphatase3 PF13350.6 RLN88154.1 - 0.00073 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 RLN88154.1 - 0.00076 19.1 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 RLN88154.1 - 0.022 14.5 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Lipase_3 PF01764.25 RLN88155.1 - 8.1e-17 61.4 0.0 1.4e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) GP67 PF17634.2 RLN88155.1 - 0.016 15.6 1.0 0.041 14.3 1.0 1.7 1 0 0 1 1 1 0 Gene product 67 PP2C PF00481.21 RLN88156.1 - 2.2e-44 152.0 0.2 7.4e-44 150.3 0.2 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RLN88156.1 - 4.5e-06 26.4 0.0 7.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C TFIIS_C PF01096.18 RLN88157.1 - 1.4e-17 63.2 1.6 3e-17 62.2 1.6 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) PA PF02225.22 RLN88157.1 - 7.3e-10 38.7 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 PA domain Zn_Tnp_IS1595 PF12760.7 RLN88157.1 - 0.028 14.4 0.8 0.049 13.6 0.8 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain eIF-5_eIF-2B PF01873.17 RLN88157.1 - 0.038 13.9 1.0 0.062 13.2 1.0 1.3 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Zn-ribbon_8 PF09723.10 RLN88157.1 - 0.039 14.1 5.1 0.58 10.3 1.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Baculo_LEF5_C PF11792.8 RLN88157.1 - 0.066 12.9 0.6 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain zf-TFIIB PF13453.6 RLN88157.1 - 0.15 11.4 1.0 0.32 10.4 1.0 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger DUF2387 PF09526.10 RLN88157.1 - 0.17 12.0 0.9 0.31 11.2 0.9 1.4 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) RNA_POL_M_15KD PF02150.16 RLN88157.1 - 0.19 11.6 4.2 1.2 9.0 4.2 2.0 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit zinc_ribbon_4 PF13717.6 RLN88157.1 - 0.44 10.5 3.4 2.9 7.9 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf_C2H2_10 PF18414.1 RLN88157.1 - 0.57 9.8 0.1 0.57 9.8 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger DUF4379 PF14311.6 RLN88157.1 - 0.64 10.4 3.4 3.7 8.0 0.1 2.9 2 1 1 3 3 3 0 Probable Zinc-ribbon domain zf_UBZ PF18439.1 RLN88157.1 - 1.2 8.8 3.7 4.2 7.0 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-ribbon_3 PF13248.6 RLN88157.1 - 1.2 8.6 4.8 6 6.4 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain HECT PF00632.25 RLN88158.1 - 3.1e-79 266.7 0.0 3.5e-79 266.5 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pectate_lyase PF03211.13 RLN88159.1 - 2e-72 243.0 6.4 2.5e-72 242.7 6.4 1.0 1 0 0 1 1 1 1 Pectate lyase Bacteriocin_II PF01721.18 RLN88159.1 - 0.82 9.8 6.2 0.13 12.4 1.6 2.1 2 0 0 2 2 2 0 Class II bacteriocin Pectate_lyase PF03211.13 RLN88160.1 - 2e-63 213.6 12.9 2.4e-63 213.4 12.9 1.1 1 0 0 1 1 1 1 Pectate lyase Lipase_GDSL_2 PF13472.6 RLN88161.1 - 5.3e-16 59.5 0.0 1.1e-15 58.4 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RLN88161.1 - 1.2e-13 51.5 0.0 5.1e-13 49.4 0.0 2.0 3 0 0 3 3 3 1 GDSL-like Lipase/Acylhydrolase ARGLU PF15346.6 RLN88161.1 - 0.092 12.6 0.4 0.16 11.8 0.4 1.3 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 HIP1_clath_bdg PF16515.5 RLN88161.1 - 0.47 11.1 3.9 1.1 9.9 3.9 1.6 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BT1 PF03092.16 RLN88162.1 - 7.4e-86 288.4 19.1 2.2e-49 168.1 6.3 3.1 1 1 1 2 2 2 2 BT1 family RabGAP-TBC PF00566.18 RLN88163.1 - 8.4e-12 45.2 1.3 8.4e-12 45.2 1.3 2.7 2 1 0 2 2 2 1 Rab-GTPase-TBC domain WD40 PF00400.32 RLN88163.1 - 0.0059 17.4 0.0 0.45 11.5 0.0 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat Fe-S_biosyn PF01521.20 RLN88166.1 - 1.8e-12 47.4 0.0 2.5e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis NADH_dh_m_C1 PF15088.6 RLN88167.1 - 0.011 15.3 6.0 0.2 11.3 0.1 4.0 4 0 0 4 4 4 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial WD40 PF00400.32 RLN88169.1 - 7.9e-28 96.1 12.6 1.2e-05 26.0 0.2 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN88169.1 - 1.6e-07 31.6 0.1 0.06 13.7 0.0 4.8 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN88169.1 - 0.0048 15.6 1.7 1.3 7.6 0.1 3.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RLN88169.1 - 0.0083 15.1 0.4 1.3 7.9 0.0 3.3 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF218 PF02698.17 RLN88169.1 - 0.017 15.1 1.1 0.046 13.7 0.2 2.2 2 0 0 2 2 2 0 DUF218 domain ATG16 PF08614.11 RLN88169.1 - 0.026 14.8 27.9 0.32 11.2 20.2 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) PQQ_3 PF13570.6 RLN88169.1 - 0.033 14.7 2.5 3 8.5 0.0 4.5 6 1 0 6 6 6 0 PQQ-like domain DUF4038 PF13204.6 RLN88170.1 - 2.1e-18 67.1 0.8 2.7e-18 66.7 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Pkinase_Tyr PF07714.17 RLN88171.1 - 3.8e-40 137.8 0.0 6.3e-40 137.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN88171.1 - 2.1e-37 129.0 0.0 3.4e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.23 RLN88171.1 - 8.7e-21 73.2 0.1 9.8e-05 22.3 0.0 6.7 6 1 0 6 6 6 5 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN88171.1 - 0.0042 17.2 0.0 45 4.7 0.0 4.9 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 RLN88171.1 - 0.018 15.5 3.2 3.5 8.2 0.2 3.3 1 1 2 3 3 3 0 HEAT-like repeat Kinase-like PF14531.6 RLN88171.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like HEAT_PBS PF03130.16 RLN88171.1 - 2 9.3 10.8 1.9e+02 3.2 0.1 6.0 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat AA_permease_2 PF13520.6 RLN88172.1 - 0.00074 18.5 7.1 0.00076 18.4 7.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN88172.1 - 0.037 12.6 5.3 0.042 12.4 5.3 1.1 1 0 0 1 1 1 0 Amino acid permease Peptidase_M1 PF01433.20 RLN88175.1 - 8.3e-49 166.1 0.0 1.2e-48 165.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 RLN88175.1 - 2.5e-26 92.0 0.0 5.2e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 RLN88175.1 - 1.3e-18 67.8 0.0 2.2e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain MIF4G PF02854.19 RLN88176.1 - 4.9e-12 45.9 0.2 8e-12 45.2 0.2 1.3 1 0 0 1 1 1 1 MIF4G domain PAM2 PF07145.15 RLN88176.1 - 0.028 14.1 3.4 1.8 8.5 0.2 2.7 2 0 0 2 2 2 0 Ataxin-2 C-terminal region TFIIA PF03153.13 RLN88176.1 - 0.18 11.7 28.1 0.26 11.3 28.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDK5_activator PF03261.15 RLN88176.1 - 4.4 6.8 13.9 7.1 6.1 13.9 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein PAT1 PF09770.9 RLN88176.1 - 4.6 5.4 22.1 6.4 4.9 22.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SWI-SNF_Ssr4 PF08549.10 RLN88176.1 - 4.8 5.7 26.3 7.3 5.1 26.3 1.4 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SID-1_RNA_chan PF13965.6 RLN88176.1 - 6.1 5.1 8.7 9.3 4.5 8.7 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Macoilin PF09726.9 RLN88176.1 - 9.4 4.6 22.4 0.052 12.1 13.9 1.7 2 0 0 2 2 2 0 Macoilin family Hydrolase_4 PF12146.8 RLN88177.1 - 6.1e-52 176.3 0.0 7.3e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN88177.1 - 1.6e-11 45.3 0.2 2.2e-11 44.8 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN88177.1 - 3.4e-09 36.7 0.1 5.4e-08 32.8 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN88177.1 - 0.00096 18.7 0.0 0.12 11.9 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 RLN88177.1 - 0.001 18.8 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DLH PF01738.18 RLN88177.1 - 0.0089 15.6 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 RLN88177.1 - 0.02 14.7 0.1 12 5.6 0.0 3.1 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase ABC_tran PF00005.27 RLN88178.1 - 8.2e-16 58.8 0.0 1.4e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 RLN88178.1 - 5.1e-05 23.7 0.0 0.00014 22.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RLN88178.1 - 0.0014 18.9 0.0 0.0032 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 RLN88178.1 - 0.0063 15.8 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 RLN88178.1 - 0.025 14.5 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase EPSP_synthase PF00275.20 RLN88178.1 - 0.034 12.9 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) AAA_30 PF13604.6 RLN88178.1 - 0.034 13.9 0.1 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 RLN88178.1 - 0.042 13.6 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain VirE PF05272.11 RLN88178.1 - 0.084 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E NACHT PF05729.12 RLN88178.1 - 0.15 11.9 0.1 0.4 10.6 0.1 1.7 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 RLN88178.1 - 0.15 11.5 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Piezo_RRas_bdg PF12166.8 RLN88179.1 - 4.8e-90 302.9 0.3 4.8e-90 302.9 0.3 1.7 2 0 0 2 2 2 1 Piezo non-specific cation channel, R-Ras-binding domain fn3 PF00041.21 RLN88179.1 - 1.8e-11 44.2 0.0 5.4e-11 42.7 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain PH PF00169.29 RLN88179.1 - 8.2e-06 26.3 0.2 3.9e-05 24.1 0.2 2.3 1 0 0 1 1 1 1 PH domain Pur_ac_phosph_N PF16656.5 RLN88179.1 - 0.0014 19.1 0.0 0.011 16.3 0.0 2.5 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain BBP1_C PF15272.6 RLN88180.1 - 0.056 13.3 1.7 0.14 12.0 1.7 1.6 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DUF724 PF05266.14 RLN88180.1 - 1.2 8.9 8.0 6.5 6.5 8.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) HAUS6_N PF14661.6 RLN88180.1 - 3.1 7.3 7.8 1.1 8.8 4.3 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus ABC2_membrane PF01061.24 RLN88182.1 - 2.5e-63 213.3 63.2 1e-32 113.3 28.1 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN88182.1 - 1.4e-16 61.2 0.0 2.3e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter PDR_CDR PF06422.12 RLN88182.1 - 5.6e-06 26.2 0.0 5.6e-06 26.2 0.0 4.5 5 0 0 5 5 3 1 CDR ABC transporter AAA_21 PF13304.6 RLN88182.1 - 7.4e-05 22.7 0.1 0.076 12.8 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 RLN88182.1 - 0.00017 20.8 47.0 0.001 18.3 18.1 2.6 3 0 0 3 3 3 2 ABC-2 family transporter protein PDR_assoc PF08370.11 RLN88182.1 - 0.0012 18.5 11.4 0.083 12.6 0.2 3.8 3 0 0 3 3 2 2 Plant PDR ABC transporter associated RsgA_GTPase PF03193.16 RLN88182.1 - 0.0034 17.3 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN88182.1 - 0.0054 16.4 0.7 0.012 15.3 0.7 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN88182.1 - 0.025 15.0 0.1 0.054 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 RLN88182.1 - 0.032 14.7 0.0 0.059 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 RLN88182.1 - 0.087 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Ubiquitin_4 PF18036.1 RLN88183.1 - 0.065 13.3 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain Acetyltransf_1 PF00583.25 RLN88184.1 - 5.5e-13 49.2 0.0 6.6e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RLN88184.1 - 4.9e-10 39.4 0.0 7.1e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN88184.1 - 1.4e-08 35.0 0.0 2.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN88184.1 - 0.00011 22.1 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 RLN88184.1 - 0.00077 19.6 0.0 0.00093 19.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 RLN88184.1 - 0.002 18.3 0.0 0.003 17.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 RLN88184.1 - 0.038 14.1 0.0 0.062 13.4 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CBM_1 PF00734.18 RLN88185.1 - 1.9e-31 107.7 48.4 7.6e-11 41.8 8.3 6.0 5 1 0 5 5 5 5 Fungal cellulose binding domain FAD_binding_4 PF01565.23 RLN88186.1 - 5.4e-25 87.7 3.5 5.4e-25 87.7 3.5 1.9 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.12 RLN88186.1 - 2.6e-18 65.8 0.2 4.9e-18 65.0 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF2046 PF09755.9 RLN88187.1 - 0.0066 15.7 0.6 0.03 13.6 0.2 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) BAR PF03114.18 RLN88187.1 - 0.016 14.9 1.6 0.017 14.8 0.2 1.9 2 0 0 2 2 2 0 BAR domain Pex19 PF04614.12 RLN88187.1 - 0.026 14.3 1.4 0.094 12.5 1.6 1.8 1 1 0 1 1 1 0 Pex19 protein family FCH PF00611.23 RLN88187.1 - 0.047 14.0 3.6 0.059 13.7 0.3 2.7 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain BAG6 PF12057.8 RLN88187.1 - 0.083 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 BCL2-associated athanogene 6 DUF5437 PF17505.2 RLN88187.1 - 0.97 9.5 3.5 1.1 9.3 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5437) HD_3 PF13023.6 RLN88188.1 - 1.4e-36 125.9 2.8 6.4e-25 88.0 0.3 2.1 2 0 0 2 2 2 2 HD domain HD_2 PF12917.7 RLN88188.1 - 9.5e-06 25.5 0.6 0.00017 21.4 0.1 2.1 2 0 0 2 2 2 1 HD containing hydrolase-like enzyme Helicase_C PF00271.31 RLN88189.1 - 4.5e-17 62.4 0.0 9.9e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RLN88189.1 - 4.5e-13 49.3 0.0 9.7e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-GRF PF06839.12 RLN88189.1 - 1.8e-11 43.9 2.0 3.9e-11 42.9 2.0 1.6 1 0 0 1 1 1 1 GRF zinc finger ResIII PF04851.15 RLN88189.1 - 0.054 13.5 0.0 0.27 11.2 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit SLS PF14611.6 RLN88189.1 - 0.13 12.1 1.5 0.22 11.3 0.5 2.0 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator HET PF06985.11 RLN88189.1 - 0.32 11.4 2.3 0.47 10.8 0.1 2.5 2 0 0 2 2 2 0 Heterokaryon incompatibility protein (HET) PX PF00787.24 RLN88190.1 - 1.6e-09 37.7 0.3 2.3e-08 34.0 0.3 2.6 1 1 0 1 1 1 1 PX domain Clusterin PF01093.17 RLN88190.1 - 0.049 12.7 0.3 1.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Clusterin Peptidase_S74 PF13884.6 RLN88192.1 - 0.16 12.3 0.0 0.45 10.9 0.0 1.8 1 0 0 1 1 1 0 Chaperone of endosialidase ZapA PF05164.13 RLN88192.1 - 9 6.8 6.6 2.2 8.7 2.2 2.3 2 0 0 2 2 2 0 Cell division protein ZapA SKN1 PF03935.15 RLN88193.1 - 4.4e-25 88.1 12.9 3.9e-14 51.9 1.2 3.3 2 1 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Kinesin PF00225.23 RLN88197.1 - 4.8e-108 361.0 0.2 4.8e-108 361.0 0.2 3.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RLN88197.1 - 2.4e-26 92.4 0.0 2.4e-26 92.4 0.0 3.5 3 0 0 3 3 3 1 Microtubule binding Ank_5 PF13857.6 RLN88197.1 - 2.8e-05 24.3 0.2 9e-05 22.7 0.2 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN88197.1 - 0.00024 21.6 0.1 0.001 19.6 0.1 2.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) DASH_Dad1 PF08649.10 RLN88197.1 - 0.0038 17.4 2.7 1.9 8.7 0.1 4.0 3 0 0 3 3 3 2 DASH complex subunit Dad1 Lebercilin PF15619.6 RLN88197.1 - 0.005 16.5 26.4 0.005 16.5 26.4 10.3 4 2 6 10 10 10 2 Ciliary protein causing Leber congenital amaurosis disease Ank PF00023.30 RLN88197.1 - 0.0071 16.7 0.1 0.025 15.0 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeat Snapin_Pallidin PF14712.6 RLN88197.1 - 0.0095 16.3 4.1 0.0095 16.3 4.1 12.3 6 3 4 13 13 13 2 Snapin/Pallidin Ank_4 PF13637.6 RLN88197.1 - 0.011 16.3 0.1 0.13 12.8 0.0 2.4 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN88197.1 - 0.038 14.5 0.1 0.15 12.7 0.1 2.1 1 0 0 1 1 1 0 Ankyrin repeat CBFD_NFYB_HMF PF00808.23 RLN88198.1 - 3.3e-26 91.4 0.1 4.3e-26 91.0 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 RLN88198.1 - 0.00064 20.1 0.1 0.0011 19.3 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 RLN88198.1 - 0.003 17.7 0.0 0.0036 17.4 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 RLN88198.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 1 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 RLN88198.1 - 0.014 15.8 0.5 0.46 11.0 0.1 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A TFIID-18kDa PF02269.16 RLN88198.1 - 0.054 13.5 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit CtaG_Cox11 PF04442.14 RLN88199.1 - 1.5e-37 128.9 1.5 1.7e-37 128.7 1.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Glyco_transf_28 PF03033.20 RLN88200.1 - 1.2e-20 73.9 0.0 4e-20 72.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain WD40 PF00400.32 RLN88200.1 - 2e-06 28.4 4.9 0.063 14.2 0.0 5.7 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN88200.1 - 0.0032 17.7 0.0 0.4 11.0 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_2 PF13639.6 RLN88201.1 - 1e-06 28.9 3.7 1e-06 28.9 3.7 2.1 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN88201.1 - 6e-06 26.0 5.6 6e-06 26.0 5.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN88201.1 - 7.2e-06 26.2 1.2 7.2e-06 26.2 1.2 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RLN88201.1 - 1.5e-05 24.9 3.6 3.3e-05 23.7 3.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RLN88201.1 - 0.0001 22.1 4.6 0.00024 20.9 4.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN88201.1 - 0.00035 20.2 0.7 0.00082 19.1 0.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 RLN88201.1 - 0.003 17.5 3.2 0.007 16.4 3.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger PHD PF00628.29 RLN88201.1 - 0.029 14.2 2.4 0.07 13.0 2.4 1.7 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.6 RLN88201.1 - 0.031 14.1 1.8 0.031 14.1 1.8 1.7 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RLN88201.1 - 0.057 13.5 0.4 0.16 12.1 0.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 RLN88201.1 - 0.068 13.0 2.3 0.22 11.4 0.8 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit PX PF00787.24 RLN88201.1 - 0.071 13.1 0.1 0.19 11.7 0.1 1.8 1 1 0 1 1 1 0 PX domain zinc_ribbon_2 PF13240.6 RLN88201.1 - 0.17 11.7 0.7 22 4.9 0.1 2.7 2 1 0 2 2 2 0 zinc-ribbon domain zf-C3H2C3 PF17122.5 RLN88201.1 - 0.24 11.4 3.8 0.71 10.0 3.8 1.9 1 0 0 1 1 1 0 Zinc-finger Zn-ribbon_8 PF09723.10 RLN88201.1 - 0.6 10.3 3.4 1.2 9.4 0.8 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Prok-RING_1 PF14446.6 RLN88201.1 - 1.2 9.1 5.2 4.3 7.3 0.8 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.6 RLN88201.1 - 4.1 7.4 7.6 1.3 8.9 3.9 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Pkinase PF00069.25 RLN88202.1 - 2.4e-57 194.3 0.0 3.8e-47 160.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN88202.1 - 2.9e-51 174.2 0.0 5e-40 137.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase FYVE PF01363.21 RLN88202.1 - 4e-14 52.5 10.1 8.4e-14 51.5 10.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN88202.1 - 0.086 13.1 10.1 0.19 12.0 10.1 1.5 1 1 0 1 1 1 0 FYVE-type zinc finger Haspin_kinase PF12330.8 RLN88202.1 - 0.1 11.5 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Siva PF05458.12 RLN88202.1 - 0.69 9.6 6.5 1.2 8.8 6.5 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-B_box PF00643.24 RLN88202.1 - 0.96 9.7 6.6 2.5 8.3 6.6 1.7 1 0 0 1 1 1 0 B-box zinc finger EMP70 PF02990.16 RLN88203.1 - 1.7e-63 215.1 0.2 2.1e-63 214.8 0.2 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 HrpF PF06266.12 RLN88203.1 - 0.19 12.1 0.1 16 5.9 0.0 2.4 2 0 0 2 2 2 0 HrpF protein LRR_4 PF12799.7 RLN88204.1 - 0.00026 21.3 0.7 0.16 12.5 0.0 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN88204.1 - 0.00057 19.6 2.2 0.0013 18.4 0.3 2.5 3 0 0 3 3 3 1 Leucine rich repeat LRR_8 PF13855.6 RLN88206.1 - 0.00014 21.5 0.2 0.025 14.4 0.1 3.3 3 1 0 3 3 3 2 Leucine rich repeat Beta_helix PF13229.6 RLN88207.1 - 7.5e-07 29.1 0.0 1.1e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 RLN88207.1 - 0.018 14.3 0.1 0.026 13.8 0.1 1.1 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Pkinase_Tyr PF07714.17 RLN88209.1 - 3.4e-07 29.8 0.0 1.7e-05 24.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN88209.1 - 1.8e-05 24.3 0.0 5.6e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pec_lyase_C PF00544.19 RLN88210.1 - 0.0081 15.8 0.1 0.012 15.3 0.1 1.2 1 0 0 1 1 1 1 Pectate lyase FdtA PF05523.11 RLN88210.1 - 0.1 12.3 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 WxcM-like, C-terminal zf-CW PF07496.15 RLN88212.1 - 2.9e-06 27.2 0.2 6.3e-06 26.1 0.2 1.6 1 0 0 1 1 1 1 CW-type Zinc Finger zf-CCCH_4 PF18044.1 RLN88213.1 - 1.1e-16 60.2 16.4 1.9e-08 33.9 5.0 2.7 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 RLN88213.1 - 1.4e-12 47.2 20.4 2.8e-06 27.2 6.0 2.7 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 RLN88213.1 - 2.9e-10 40.8 8.1 1.2e-05 26.0 1.0 3.0 1 1 1 2 2 2 2 Torus domain zf-CCCH PF00642.24 RLN88213.1 - 4e-10 39.3 16.2 2.6e-05 24.0 5.2 3.0 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CHY PF05495.12 RLN88213.1 - 2.1e-09 37.7 12.4 2.1e-09 37.7 12.4 4.4 4 1 0 5 5 5 1 CHY zinc finger Myb_DNA-binding PF00249.31 RLN88213.1 - 0.00011 22.3 1.0 0.00088 19.4 0.0 2.7 3 0 0 3 3 3 1 Myb-like DNA-binding domain zf-CCCH_2 PF14608.6 RLN88213.1 - 0.00017 21.9 18.2 0.04 14.4 4.5 2.7 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger RWD PF05773.22 RLN88213.1 - 0.00051 20.3 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 RWD domain Myb_DNA-bind_6 PF13921.6 RLN88213.1 - 0.066 13.5 0.0 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain zf-CCCH_3 PF15663.5 RLN88213.1 - 2.6 8.3 17.8 0.16 12.2 0.6 3.5 4 0 0 4 4 4 0 Zinc-finger containing family Effector_1 PF04518.12 RLN88214.1 - 0.061 12.4 0.0 0.085 12.0 0.0 1.2 1 0 0 1 1 1 0 Effector from type III secretion system EMP70 PF02990.16 RLN88215.1 - 4e-214 712.1 13.7 5.6e-214 711.6 13.7 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Acyltransferase PF01553.21 RLN88216.1 - 7.3e-18 64.5 0.0 1.3e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Tubulin PF00091.25 RLN88218.1 - 8.8e-35 120.7 0.1 1.3e-34 120.1 0.1 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 RLN88218.1 - 2.8e-30 104.4 5.2 3.1e-20 72.3 0.0 3.5 3 1 0 3 3 3 2 FtsZ family, C-terminal domain PX PF00787.24 RLN88219.1 - 2.1e-08 34.1 0.0 4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 PX domain TMEM52 PF14979.6 RLN88220.1 - 0.00032 20.6 0.0 0.00049 20.1 0.0 1.2 1 0 0 1 1 1 1 Transmembrane 52 DUF1084 PF06454.11 RLN88220.1 - 0.12 11.7 0.0 0.14 11.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1084) NAM-associated PF14303.6 RLN88221.1 - 5.2 7.8 14.4 70 4.1 14.4 2.2 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Paf1 PF03985.13 RLN88222.1 - 1.7e-67 228.3 0.7 1.7e-67 228.3 0.7 1.6 2 0 0 2 2 2 1 Paf1 ROK PF00480.20 RLN88223.1 - 5.4e-13 49.1 0.0 1.2e-10 41.4 0.0 2.0 2 0 0 2 2 2 2 ROK family BcrAD_BadFG PF01869.20 RLN88223.1 - 3.8e-06 26.6 0.5 5.1e-06 26.2 0.5 1.1 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 RLN88223.1 - 0.00013 21.6 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain AAA PF00004.29 RLN88224.1 - 7.4e-41 139.7 0.0 1.5e-40 138.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RLN88224.1 - 4.3e-11 42.4 0.0 1.9e-10 40.3 0.0 2.2 2 0 0 2 2 1 1 AAA+ lid domain RuvB_N PF05496.12 RLN88224.1 - 3.1e-09 36.8 0.0 5.8e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RLN88224.1 - 3.1e-05 24.2 2.1 0.0002 21.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RLN88224.1 - 4.3e-05 23.8 0.1 0.13 12.5 0.0 2.8 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 RLN88224.1 - 5e-05 23.3 0.1 0.00047 20.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Nucleolin_bd PF16725.5 RLN88224.1 - 0.00021 20.9 0.1 0.00056 19.5 0.1 1.7 1 0 0 1 1 1 1 Nucleolin binding domain TIP49 PF06068.13 RLN88224.1 - 0.00058 19.2 0.0 0.00099 18.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 RLN88224.1 - 0.00095 19.3 0.0 0.0057 16.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 RLN88224.1 - 0.0014 19.1 7.7 0.0041 17.5 0.1 3.7 3 1 1 4 4 4 1 AAA ATPase domain AAA_25 PF13481.6 RLN88224.1 - 0.002 17.8 3.0 0.31 10.6 0.1 3.1 2 1 1 3 3 3 2 AAA domain Mg_chelatase PF01078.21 RLN88224.1 - 0.0046 16.4 0.2 0.013 14.8 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 RLN88224.1 - 0.0051 16.6 0.1 0.014 15.2 0.0 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 RLN88224.1 - 0.0069 16.3 0.4 0.075 12.9 0.0 2.7 2 1 1 3 3 3 1 NACHT domain RNA_helicase PF00910.22 RLN88224.1 - 0.01 16.2 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Vps4_C PF09336.10 RLN88224.1 - 0.011 15.8 0.7 0.041 13.9 0.1 2.3 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain ABC_tran PF00005.27 RLN88224.1 - 0.026 15.0 0.5 0.18 12.3 0.0 2.4 2 1 1 3 3 3 0 ABC transporter AAA_18 PF13238.6 RLN88224.1 - 0.059 13.9 0.0 0.25 11.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 RLN88224.1 - 0.071 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DDE_Tnp_IS66 PF03050.14 RLN88224.1 - 0.075 12.5 2.6 0.13 11.7 2.6 1.4 1 0 0 1 1 1 0 Transposase IS66 family AAA_28 PF13521.6 RLN88224.1 - 0.079 13.2 0.9 0.23 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 RLN88224.1 - 0.089 11.9 0.0 0.27 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) CPT PF07931.12 RLN88224.1 - 0.11 12.4 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Sigma54_activat PF00158.26 RLN88224.1 - 0.12 12.1 0.0 0.45 10.2 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Hydin_ADK PF17213.3 RLN88224.1 - 0.22 11.8 10.1 1.3 9.2 0.0 3.3 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Aldo_ket_red PF00248.21 RLN88225.1 - 2.1e-68 230.7 0.0 2.5e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 5_nucleotid_C PF02872.18 RLN88226.1 - 1.4e-18 67.6 0.0 2.5e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 RLN88226.1 - 2.8e-07 31.3 0.0 4.9e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ferlin_C PF16165.5 RLN88227.1 - 0.0058 16.6 1.9 0.0058 16.6 1.9 1.7 2 0 0 2 2 2 1 Ferlin C-terminus CBS PF00571.28 RLN88228.1 - 3.2e-114 373.4 60.6 1.9e-07 31.4 0.3 21.8 22 0 0 22 22 22 18 CBS domain PB1 PF00564.24 RLN88228.1 - 2.2e-09 37.1 0.1 6.3e-09 35.7 0.1 1.8 1 0 0 1 1 1 1 PB1 domain IQ PF00612.27 RLN88228.1 - 6.5e-05 22.4 8.8 0.052 13.4 0.0 3.7 3 0 0 3 3 3 2 IQ calmodulin-binding motif Myosin_head PF00063.21 RLN88228.1 - 0.00043 18.6 0.0 0.0006 18.2 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DUF4808 PF16066.5 RLN88228.1 - 0.031 14.8 5.1 1 9.9 0.4 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4808) LUC7 PF03194.15 RLN88228.1 - 0.58 9.8 14.5 5.9 6.5 7.2 2.9 1 1 0 2 2 2 0 LUC7 N_terminus HlyD_2 PF12700.7 RLN88228.1 - 1.9 7.1 13.5 3.2 6.4 5.0 2.3 1 1 1 2 2 2 0 HlyD family secretion protein DUF1192 PF06698.11 RLN88228.1 - 3.4 7.8 17.9 0.24 11.5 2.8 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Pox_F11 PF04943.12 RLN88228.1 - 6 5.8 7.5 18 4.3 7.5 1.8 1 0 0 1 1 1 0 Poxvirus F11 protein STIMATE PF12400.8 RLN88229.1 - 5.8e-36 123.8 3.5 9.1e-36 123.2 3.5 1.3 1 0 0 1 1 1 1 STIMATE family EGF_2 PF07974.13 RLN88230.1 - 4.8e-05 23.6 61.9 0.0047 17.3 9.9 5.9 6 0 0 6 6 6 4 EGF-like domain EGF PF00008.27 RLN88230.1 - 0.008 16.5 6.8 0.008 16.5 6.8 6.3 6 1 1 7 7 7 3 EGF-like domain Laminin_EGF PF00053.24 RLN88230.1 - 2.7 8.2 50.1 0.5 10.6 0.4 4.7 5 1 1 6 6 6 0 Laminin EGF domain cEGF PF12662.7 RLN88230.1 - 8.9 6.4 23.3 4.1 7.4 0.2 5.1 4 0 0 4 4 4 0 Complement Clr-like EGF-like Myotub-related PF06602.14 RLN88232.1 - 1.7e-129 431.8 0.1 2.5e-129 431.2 0.1 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 RLN88232.1 - 7.3e-06 25.8 0.0 1.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Y_phosphatase3 PF13350.6 RLN88232.1 - 0.066 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DivIC PF04977.15 RLN88232.1 - 0.24 11.2 1.7 0.53 10.1 1.7 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF1664 PF07889.12 RLN88232.1 - 0.27 11.3 0.9 0.71 9.9 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ZapB PF06005.12 RLN88232.1 - 1.1 9.8 6.2 2.9 8.4 6.2 1.7 1 0 0 1 1 1 0 Cell division protein ZapB C2 PF00168.30 RLN88233.1 - 3.4e-10 40.1 0.0 4.1e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 C2 domain TPR_12 PF13424.6 RLN88234.1 - 6.1e-06 26.4 20.8 0.0013 19.0 4.1 4.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN88234.1 - 0.0019 17.9 4.2 1.4 8.8 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 RLN88234.1 - 0.2 10.7 0.9 0.29 10.1 0.9 1.2 1 0 0 1 1 1 0 Coatomer WD associated region LRR_8 PF13855.6 RLN88235.1 - 2.9e-22 78.2 10.6 3.9e-08 32.9 0.7 4.4 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 RLN88235.1 - 7.1e-16 58.1 15.6 6.1e-07 29.7 1.1 5.8 2 1 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN88235.1 - 1.1e-06 28.3 8.6 1.5 9.6 0.3 6.6 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 RLN88235.1 - 1.5e-05 24.7 5.7 9.7 6.5 0.0 5.4 5 0 0 5 5 5 3 Leucine Rich repeat LRR_9 PF14580.6 RLN88235.1 - 0.0001 21.9 7.1 0.0043 16.6 0.9 2.6 1 1 0 2 2 2 2 Leucine-rich repeat Nyv1_N PF09426.10 RLN88235.1 - 0.023 14.7 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Vacuolar R-SNARE Nyv1 N terminal zf-RING_6 PF14835.6 RLN88236.1 - 3 7.8 12.3 7.9 6.4 12.3 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Methyltrn_RNA_3 PF02598.17 RLN88237.1 - 2.1e-104 349.1 0.0 2.8e-104 348.7 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methyltransferase DUF2486 PF10667.9 RLN88237.1 - 0.031 14.5 14.2 0.046 14.0 14.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) FAM60A PF15396.6 RLN88237.1 - 0.062 13.3 3.6 0.073 13.1 1.6 1.9 2 0 0 2 2 2 0 Protein Family FAM60A MCM_bind PF09739.9 RLN88237.1 - 0.096 11.1 5.8 0.13 10.7 5.8 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF601 PF04642.12 RLN88237.1 - 0.14 11.7 12.7 0.21 11.1 12.7 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Presenilin PF01080.17 RLN88237.1 - 1 8.0 6.9 1.3 7.8 6.9 1.1 1 0 0 1 1 1 0 Presenilin UCMA PF17085.5 RLN88237.1 - 5.6 7.0 12.2 8.5 6.4 10.7 1.8 2 0 0 2 2 2 0 Unique cartilage matrix associated protein Vfa1 PF08432.10 RLN88237.1 - 9 6.6 15.5 15 5.8 15.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Guanylate_cyc PF00211.20 RLN88238.1 - 1.1e-09 38.2 0.0 9.6e-09 35.1 0.0 2.1 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Endosulfine PF04667.17 RLN88239.1 - 1.4e-26 92.4 3.3 4.4e-10 39.6 0.0 4.9 4 1 0 4 4 4 4 cAMP-regulated phosphoprotein/endosulfine conserved region EF-hand_1 PF00036.32 RLN88240.1 - 7.6e-42 137.8 14.2 2.9e-10 38.9 1.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RLN88240.1 - 1e-35 122.0 3.4 5.3e-18 65.2 1.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RLN88240.1 - 1.6e-32 111.1 12.1 2.1e-16 59.5 0.9 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 RLN88240.1 - 2.2e-30 101.9 7.7 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RLN88240.1 - 8.7e-27 91.4 10.5 2.3e-06 26.8 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 RLN88240.1 - 2.2e-16 59.9 0.2 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 RLN88240.1 - 7.2e-10 38.8 0.8 0.00014 21.8 0.2 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RLN88240.1 - 2e-08 34.5 0.0 0.0022 18.3 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 RLN88240.1 - 4.2e-07 30.8 0.0 0.00016 22.5 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 RLN88240.1 - 8.7e-06 25.7 0.9 0.042 13.9 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 RLN88240.1 - 6.4e-05 23.0 1.0 0.00037 20.5 0.1 2.4 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 RLN88240.1 - 0.00027 21.0 3.9 0.045 13.9 0.3 2.8 1 1 0 2 2 2 2 Dockerin type I domain RNA_pol_Rpb4 PF03874.16 RLN88240.1 - 0.0013 19.0 0.4 0.73 10.2 0.1 2.5 3 0 0 3 3 2 1 RNA polymerase Rpb4 TerB PF05099.13 RLN88240.1 - 0.0017 18.3 0.3 0.58 10.1 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB DUF1103 PF06513.11 RLN88240.1 - 0.0019 17.9 2.1 0.0022 17.7 2.1 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF3349 PF11829.8 RLN88240.1 - 0.0019 18.9 0.4 1.2 10.0 0.0 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 RLN88240.1 - 0.0024 17.8 1.4 0.49 10.3 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein DUF5580 PF17743.1 RLN88240.1 - 0.0074 14.9 0.0 0.0074 14.9 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) DUF853 PF05872.12 RLN88240.1 - 0.022 13.4 0.1 0.6 8.6 0.0 2.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Poly_export PF02563.16 RLN88240.1 - 0.028 14.6 0.1 4.1 7.7 0.0 3.1 1 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein SurA_N_2 PF13623.6 RLN88240.1 - 0.029 14.2 0.6 1.7 8.5 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain MotA_activ PF09114.10 RLN88240.1 - 0.035 14.2 0.4 0.54 10.4 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 RLN88240.1 - 0.047 12.9 0.1 3.8 6.6 0.1 2.2 1 1 0 2 2 2 0 Cache domain Fe_hyd_lg_C PF02906.14 RLN88240.1 - 0.061 13.0 1.0 0.24 11.0 1.0 1.9 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain EF-hand_14 PF17959.1 RLN88240.1 - 0.075 13.4 0.2 9.2 6.7 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain SapB_1 PF05184.15 RLN88240.1 - 0.27 11.3 2.7 27 4.9 0.0 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 1 DUF2063 PF09836.9 RLN88241.1 - 0.028 14.6 0.1 0.39 11.0 0.0 2.2 2 0 0 2 2 2 0 Putative DNA-binding domain DAHP_synth_2 PF01474.16 RLN88242.1 - 6.3e-189 628.0 0.0 7.1e-189 627.8 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family MIG-14_Wnt-bd PF06664.12 RLN88243.1 - 4.3e-63 213.3 21.3 4.3e-63 213.3 21.3 1.4 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Tail_tube PF10618.9 RLN88243.1 - 0.082 12.8 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 Phage tail tube protein Cpn60_TCP1 PF00118.24 RLN88244.1 - 8.9e-157 522.6 5.1 1e-156 522.4 5.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TraH_2 PF06871.11 RLN88244.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 TraH_2 ISN1 PF06437.11 RLN88244.1 - 0.063 12.2 0.1 0.11 11.3 0.1 1.4 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase TMP-TENI PF02581.17 RLN88245.1 - 1.3e-25 89.8 4.6 1.5e-25 89.6 4.6 1.1 1 0 0 1 1 1 1 Thiamine monophosphate synthase ThiG PF05690.14 RLN88245.1 - 2.3e-05 23.8 0.4 2.3e-05 23.8 0.4 1.5 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG NMO PF03060.15 RLN88245.1 - 7e-05 22.4 4.9 0.00016 21.2 4.9 1.6 1 1 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 RLN88245.1 - 8.7e-05 22.1 0.8 0.3 10.5 0.3 2.4 1 1 1 2 2 2 2 Histidine biosynthesis protein DHO_dh PF01180.21 RLN88245.1 - 0.0055 15.9 1.9 0.12 11.6 0.4 2.1 1 1 1 2 2 2 2 Dihydroorotate dehydrogenase SKN1 PF03935.15 RLN88246.1 - 1.2e-58 198.8 16.7 3e-40 138.1 6.1 4.6 2 2 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Toxin_2 PF00451.19 RLN88246.1 - 0.21 11.9 1.9 0.88 9.9 1.9 2.2 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 BT1 PF03092.16 RLN88248.1 - 2e-19 69.3 17.9 1.6e-14 53.1 1.8 3.2 3 0 0 3 3 3 3 BT1 family DUF5083 PF16890.5 RLN88248.1 - 0.19 11.5 5.3 4.3 7.1 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5083) PPR_2 PF13041.6 RLN88253.1 - 1.5e-46 156.4 10.1 1.6e-15 57.0 0.0 9.5 5 3 6 11 11 11 11 PPR repeat family PPR PF01535.20 RLN88253.1 - 2.3e-42 140.3 13.8 4.5e-08 32.8 0.0 11.9 11 1 0 11 11 11 9 PPR repeat PPR_1 PF12854.7 RLN88253.1 - 1.1e-41 140.1 0.8 8.4e-11 41.4 0.1 10.3 10 0 0 10 10 10 8 PPR repeat PPR_3 PF13812.6 RLN88253.1 - 8e-37 125.1 9.6 2.1e-08 34.1 0.0 8.4 6 2 4 10 10 10 8 Pentatricopeptide repeat domain PPR_long PF17177.4 RLN88253.1 - 3.1e-19 69.2 15.1 1.4e-12 47.4 0.6 5.0 2 2 4 6 6 6 4 Pentacotripeptide-repeat region of PRORP Vps39_1 PF10366.9 RLN88253.1 - 6e-05 23.3 0.5 2.1 8.7 0.1 4.2 3 1 0 3 3 3 2 Vacuolar sorting protein 39 domain 1 MRP-S27 PF10037.9 RLN88253.1 - 0.0085 15.0 0.2 0.92 8.3 0.0 3.4 2 2 0 3 3 3 1 Mitochondrial 28S ribosomal protein S27 COX5A PF02284.16 RLN88253.1 - 0.085 12.9 0.2 4.3 7.4 0.0 3.2 2 2 0 3 3 3 0 Cytochrome c oxidase subunit Va BSP_II PF05432.11 RLN88253.1 - 1.2 8.7 8.5 0.086 12.5 1.4 2.0 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) TPR_14 PF13428.6 RLN88253.1 - 1.8 9.6 27.8 1.9 9.5 0.0 7.9 7 2 2 9 9 9 0 Tetratricopeptide repeat Proton_antipo_N PF00662.20 RLN88254.1 - 0.029 14.4 1.3 11 6.1 0.2 3.8 3 0 0 3 3 3 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus APOBEC_C PF05240.14 RLN88254.1 - 0.07 13.1 0.0 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 APOBEC-like C-terminal domain DUF2053 PF09767.9 RLN88254.1 - 1.1 9.4 11.3 0.98 9.6 0.6 3.5 4 0 0 4 4 4 0 Predicted membrane protein (DUF2053) BT1 PF03092.16 RLN88255.1 - 8.3e-12 44.1 15.1 4.5e-08 31.8 1.0 3.2 3 0 0 3 3 3 3 BT1 family ERGIC_N PF13850.6 RLN88255.1 - 0.82 10.1 2.7 11 6.4 0.0 3.5 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Cyt_bd_oxida_II PF02322.15 RLN88255.1 - 4.3 6.6 30.5 0.043 13.2 17.1 3.1 2 1 0 3 3 3 0 Cytochrome bd terminal oxidase subunit II LRR_4 PF12799.7 RLN88256.1 - 5.5e-15 55.2 10.4 0.0049 17.3 0.0 5.7 3 1 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN88256.1 - 2e-14 53.5 0.1 3.9e-10 39.5 0.0 3.1 1 1 3 4 4 4 2 Leucine-rich repeat LRR_8 PF13855.6 RLN88256.1 - 2.6e-10 39.9 10.3 0.0026 17.5 0.2 5.3 3 2 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 RLN88256.1 - 9.7e-06 25.3 7.6 4.5 7.6 0.1 7.1 7 0 0 7 7 7 1 Leucine Rich repeat LRR_1 PF00560.33 RLN88256.1 - 0.0042 17.4 3.2 39 5.4 0.1 6.3 7 0 0 7 7 7 0 Leucine Rich Repeat CAP_GLY PF01302.25 RLN88256.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 CAP-Gly domain Ubiquitin_2 PF14560.6 RLN88256.1 - 0.11 12.9 0.0 0.39 11.2 0.0 2.0 1 1 0 1 1 1 0 Ubiquitin-like domain Aldo_ket_red PF00248.21 RLN88259.1 - 6.7e-69 232.3 0.0 7.5e-69 232.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TGase_elicitor PF16683.5 RLN88260.1 - 4.4e-78 262.6 0.1 4.8e-78 262.5 0.1 1.0 1 0 0 1 1 1 1 Transglutaminase elicitor Endostatin PF06482.11 RLN88261.1 - 10 5.5 7.8 4.7 6.6 2.3 2.1 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin SpoIIE PF07228.12 RLN88262.1 - 7.2e-14 52.1 0.6 2.9e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) CBS PF00571.28 RLN88262.1 - 2.3e-11 44.0 0.2 3.5e-07 30.5 0.2 2.7 2 0 0 2 2 2 2 CBS domain PPTA PF01239.22 RLN88262.1 - 2.5e-09 36.5 0.1 0.001 18.7 0.0 2.7 2 0 0 2 2 2 2 Protein prenyltransferase alpha subunit repeat PP2C PF00481.21 RLN88262.1 - 0.003 17.2 0.1 0.092 12.4 0.0 2.5 2 0 0 2 2 2 1 Protein phosphatase 2C TPR_14 PF13428.6 RLN88262.1 - 0.051 14.4 0.3 2.6 9.1 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat HTH_OrfB_IS605 PF12323.8 RLN88263.1 - 9e-06 25.1 0.0 2.7e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain OrfB_IS605 PF01385.19 RLN88263.1 - 0.00011 22.5 1.4 0.00011 22.5 1.4 2.8 2 1 0 2 2 2 1 Probable transposase Ferric_reduct PF01794.19 RLN88264.1 - 2.5e-17 63.2 11.8 5.4e-17 62.1 11.8 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 RLN88264.1 - 4.4e-07 30.1 0.0 9.9e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 RLN88264.1 - 0.018 15.7 0.0 0.054 14.1 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Cyt_bd_oxida_II PF02322.15 RLN88264.1 - 4.6 6.5 18.4 0.25 10.7 12.1 1.7 1 1 1 2 2 2 0 Cytochrome bd terminal oxidase subunit II MerE PF05052.12 RLN88265.1 - 0.00085 19.2 2.0 0.00085 19.2 2.0 2.2 2 0 0 2 2 2 1 MerE protein FAM176 PF14851.6 RLN88265.1 - 0.024 14.3 7.1 0.019 14.6 2.0 2.4 1 1 1 2 2 2 0 FAM176 family HupE_UreJ_2 PF13795.6 RLN88265.1 - 0.027 14.1 0.4 0.027 14.1 0.4 2.5 3 0 0 3 3 3 0 HupE / UreJ protein eIF-3c_N PF05470.12 RLN88265.1 - 6.1 5.0 6.5 8.2 4.6 6.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Spore_coat_CotO PF14153.6 RLN88265.1 - 9 6.2 7.6 7.7 6.4 6.4 1.4 1 1 0 1 1 1 0 Spore coat protein CotO FoP_duplication PF13865.6 RLN88266.1 - 8.8e-19 67.8 14.3 8.8e-19 67.8 14.3 2.7 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 DUF5580 PF17743.1 RLN88266.1 - 1.6 7.2 5.7 2 6.9 5.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Guanylate_cyc PF00211.20 RLN88267.1 - 2.2e-08 33.9 0.0 3.7e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TB2_DP1_HVA22 PF03134.19 RLN88268.1 - 6.2e-12 45.3 1.5 1.2e-11 44.4 1.5 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family adh_short PF00106.25 RLN88269.1 - 0.068 12.6 0.0 0.086 12.3 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase ChapFlgA_N PF17656.1 RLN88270.1 - 0.05 13.8 0.1 0.72 10.1 0.1 2.3 1 1 1 2 2 2 0 FlgA N-terminal domain bZIP_2 PF07716.15 RLN88271.1 - 3.8e-07 30.1 0.6 3.8e-07 30.1 0.6 2.2 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 RLN88271.1 - 3.8e-06 26.9 0.8 3.8e-06 26.9 0.8 1.7 2 0 0 2 2 2 1 bZIP transcription factor Ribosomal_L38e PF01781.18 RLN88271.1 - 0.097 12.8 0.2 0.15 12.2 0.2 1.2 1 0 0 1 1 1 0 Ribosomal L38e protein family STIMATE PF12400.8 RLN88272.1 - 4.1e-24 85.5 4.9 4.1e-24 85.5 4.9 1.7 1 1 1 2 2 2 1 STIMATE family Pkinase_Tyr PF07714.17 RLN88274.1 - 5.7e-42 143.8 0.0 9.1e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN88274.1 - 1.7e-37 129.2 0.0 3e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.23 RLN88274.1 - 4.1e-18 64.8 13.8 0.0021 18.0 0.0 9.0 9 0 0 9 9 9 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN88274.1 - 2.4e-06 27.9 22.0 0.00099 19.6 0.6 6.7 6 1 1 7 7 7 3 HEAT-like repeat HEAT PF02985.22 RLN88274.1 - 2.2e-05 24.3 8.2 5.9 7.4 0.0 7.0 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 RLN88274.1 - 0.00065 20.0 23.7 0.017 15.5 2.3 5.0 2 2 3 6 6 6 3 HEAT repeats Pkinase_fungal PF17667.1 RLN88274.1 - 0.03 13.1 0.0 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Ank_2 PF12796.7 RLN88275.1 - 4.2e-123 402.2 20.2 1.1e-21 77.2 0.2 8.2 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN88275.1 - 1.3e-95 312.6 23.9 2.4e-10 40.7 0.1 10.8 4 2 9 13 13 13 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN88275.1 - 9.4e-83 262.2 6.4 0.00011 22.4 0.0 16.4 17 0 0 17 17 17 14 Ankyrin repeat Ank PF00023.30 RLN88275.1 - 1.1e-81 266.0 18.0 4.4e-06 26.9 0.0 15.9 16 0 0 16 16 16 14 Ankyrin repeat Ank_5 PF13857.6 RLN88275.1 - 3.3e-78 256.7 26.6 1.3e-07 31.8 0.1 13.6 2 2 13 15 15 15 15 Ankyrin repeats (many copies) DUF2390 PF09523.10 RLN88275.1 - 0.0019 18.5 4.6 6.2 7.2 0.2 4.6 1 1 4 5 5 5 1 Protein of unknown function (DUF2390) YlzJ PF14035.6 RLN88275.1 - 0.0028 17.8 0.0 1.4e+02 2.8 0.0 6.1 9 0 0 9 9 9 0 YlzJ-like protein YfmQ PF10787.9 RLN88275.1 - 0.0037 17.0 0.0 7.6 6.3 0.0 4.9 2 1 2 5 5 5 1 Uncharacterised protein from bacillus cereus group DUF3863 PF12979.7 RLN88275.1 - 0.0046 15.8 7.9 2 7.2 0.1 4.1 3 1 0 4 4 4 1 Domain of Unknown Function with PDB structure (DUF3863) tRNA_NucTran2_2 PF13735.6 RLN88275.1 - 0.035 14.1 3.7 6.9 6.6 0.0 3.8 1 1 4 5 5 5 0 tRNA nucleotidyltransferase domain 2 putative Nepo_coat_C PF03688.14 RLN88275.1 - 0.16 11.8 1.3 58 3.5 0.0 4.2 2 1 4 6 6 6 0 Nepovirus coat protein, C-terminal domain SBP_bac_3 PF00497.20 RLN88275.1 - 1.4 8.3 4.4 23 4.3 0.1 3.3 2 1 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 3HCDH_RFF PF18321.1 RLN88275.1 - 1.9 9.0 15.1 28 5.2 0.0 6.9 6 2 3 9 9 9 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Glyoxalase_6 PF18029.1 RLN88275.1 - 6.7 7.6 8.8 19 6.1 0.2 3.5 2 1 0 2 2 2 0 Glyoxalase-like domain ATG16 PF08614.11 RLN88281.1 - 0.00014 22.2 17.8 0.00014 22.2 17.8 10.3 4 2 6 10 10 10 3 Autophagy protein 16 (ATG16) Sec2p PF06428.11 RLN88281.1 - 0.0078 16.2 3.8 0.0078 16.2 3.8 10.6 5 1 5 11 11 11 2 GDP/GTP exchange factor Sec2p Glyco_hydro_3 PF00933.21 RLN88282.1 - 1.9e-52 178.6 0.0 2.5e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN88282.1 - 1.2e-38 133.2 0.0 2.8e-38 131.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RLN88282.1 - 1.6e-13 50.5 0.1 2.9e-13 49.7 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_1 PF00232.18 RLN88284.1 - 1.1e-165 551.5 0.1 1.2e-165 551.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF4586 PF15239.6 RLN88285.1 - 2.4e-58 198.7 1.8 2.8e-58 198.5 1.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) CC190 PF15768.5 RLN88285.1 - 0.16 12.0 0.5 0.28 11.2 0.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 ADH_zinc_N_2 PF13602.6 RLN88286.1 - 1.6e-19 71.3 0.1 1.4e-18 68.2 0.0 2.5 3 1 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 RLN88286.1 - 1.3e-12 47.8 0.0 4.1e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN88286.1 - 6.8e-09 35.6 0.0 1.4e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_16 PF10294.9 RLN88286.1 - 0.0054 16.5 0.1 0.0094 15.7 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Eno-Rase_NADH_b PF12242.8 RLN88286.1 - 0.021 14.6 0.4 0.042 13.6 0.4 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_hydro_1 PF00232.18 RLN88288.1 - 1.6e-165 550.9 0.0 1.9e-165 550.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_1 PF00232.18 RLN88289.1 - 9.1e-163 541.9 2.2 1e-162 541.7 2.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Ribosomal_L4 PF00573.22 RLN88290.1 - 5.3e-40 137.2 0.7 8.5e-40 136.5 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 RLN88290.1 - 1.9e-27 95.1 0.8 1.9e-27 95.1 0.8 2.3 1 1 1 2 2 2 1 60S ribosomal protein L4 C-terminal domain Neur PF00064.18 RLN88290.1 - 0.06 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Neuraminidase Rep_fac_C PF08542.11 RLN88292.1 - 1.8e-21 76.3 0.0 4.4e-21 75.1 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 RLN88292.1 - 2.8e-13 50.0 0.3 4.6e-11 42.8 0.2 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 RLN88292.1 - 4.4e-13 49.8 0.1 8e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 RLN88292.1 - 9.9e-07 28.9 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 RLN88292.1 - 4e-06 26.9 0.0 6.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RLN88292.1 - 1e-05 25.8 0.4 0.0049 17.1 0.4 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RLN88292.1 - 1.2e-05 25.8 0.3 0.0013 19.1 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 RLN88292.1 - 6.4e-05 22.4 0.2 0.00084 18.8 0.1 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 RLN88292.1 - 6.8e-05 22.7 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 RLN88292.1 - 9.4e-05 22.3 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RLN88292.1 - 0.00019 21.8 0.6 0.00066 20.0 0.5 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 RLN88292.1 - 0.00037 20.1 0.1 0.0014 18.2 0.1 1.9 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RLN88292.1 - 0.00069 19.4 0.8 0.0019 17.9 0.8 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 RLN88292.1 - 0.0021 17.8 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 RLN88292.1 - 0.0025 17.6 0.0 0.0093 15.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 RLN88292.1 - 0.0037 17.2 0.2 0.042 13.7 0.0 2.2 1 1 1 2 2 2 1 RsgA GTPase AAA_assoc_2 PF16193.5 RLN88292.1 - 0.0038 17.5 0.0 0.012 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain MeaB PF03308.16 RLN88292.1 - 0.0039 16.2 0.2 0.0096 14.9 0.2 1.6 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 RLN88292.1 - 0.0052 17.3 0.1 0.015 15.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 RLN88292.1 - 0.0052 17.3 0.0 0.013 16.1 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_3 PF07726.11 RLN88292.1 - 0.0095 15.8 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RLN88292.1 - 0.0098 15.9 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TniB PF05621.11 RLN88292.1 - 0.017 14.5 0.1 0.88 9.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein DEAD PF00270.29 RLN88292.1 - 0.018 14.8 0.8 1.6 8.5 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase TIP49 PF06068.13 RLN88292.1 - 0.021 14.0 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 RLN88292.1 - 0.03 13.8 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region ResIII PF04851.15 RLN88292.1 - 0.039 14.0 0.1 6 6.8 0.1 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 RLN88292.1 - 0.051 13.3 0.1 0.13 12.0 0.1 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.20 RLN88292.1 - 0.059 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.15 RLN88292.1 - 0.069 13.1 0.2 0.31 11.0 0.1 1.9 1 1 1 2 2 2 0 NTPase DUF2075 PF09848.9 RLN88292.1 - 0.13 11.5 0.7 1.6 7.9 0.7 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 RLN88292.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 RLN88292.1 - 0.17 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit PhoH PF02562.16 RLN88292.1 - 0.17 11.3 1.0 3.8 6.9 0.1 2.3 1 1 0 2 2 2 0 PhoH-like protein IFRD PF05004.13 RLN88293.1 - 4.3e-40 137.7 0.1 6.2e-40 137.2 0.1 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) CDPS PF16715.5 RLN88293.1 - 0.044 13.4 0.4 0.083 12.5 0.4 1.4 1 0 0 1 1 1 0 Cyclodipeptide synthase SARAF PF06682.12 RLN88294.1 - 0.13 11.9 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis HSP70 PF00012.20 RLN88295.1 - 1.9e-46 158.5 0.9 2.1e-46 158.3 0.9 1.0 1 0 0 1 1 1 1 Hsp70 protein SANT_DAMP1_like PF16282.5 RLN88296.1 - 9.3e-27 93.1 1.4 2.1e-26 91.9 1.4 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 RLN88296.1 - 6.9e-15 55.3 1.9 6.9e-15 55.3 1.9 2.2 2 1 0 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-binding PF00249.31 RLN88296.1 - 3.5e-05 23.9 0.0 0.0001 22.4 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN88296.1 - 9.7e-05 22.5 0.2 0.00092 19.4 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Actin PF00022.19 RLN88296.1 - 0.081 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Actin Med7 PF05983.11 RLN88296.1 - 0.085 12.9 0.0 0.085 12.9 0.0 2.2 3 0 0 3 3 3 0 MED7 protein zf-C3HC PF07967.13 RLN88298.1 - 9.2e-25 87.2 1.0 4.3e-20 72.1 0.0 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 RLN88298.1 - 2e-05 24.6 10.7 5.4e-05 23.3 0.5 3.3 3 0 0 3 3 3 2 Rsm1-like RRM_1 PF00076.22 RLN88299.1 - 1.8e-16 59.7 0.0 2.8e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RLN88299.1 - 0.0081 15.7 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KASH_CCD PF14662.6 RLN88299.1 - 0.013 15.3 2.8 0.019 14.8 2.8 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Spectrin PF00435.21 RLN88299.1 - 0.014 15.9 1.4 1.1 9.8 1.5 2.4 2 1 1 3 3 3 0 Spectrin repeat HAUS-augmin3 PF14932.6 RLN88299.1 - 0.02 14.4 1.2 0.029 13.9 1.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 GPS2_interact PF15784.5 RLN88299.1 - 0.074 13.5 3.0 0.085 13.3 2.3 1.5 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF812 PF05667.11 RLN88299.1 - 0.099 11.5 1.8 0.11 11.3 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) GRP PF07172.11 RLN88299.1 - 6.6 7.5 13.6 0.66 10.7 7.2 2.1 2 0 0 2 2 2 0 Glycine rich protein family DAO PF01266.24 RLN88301.1 - 3.6e-29 102.4 2.9 3.7e-17 62.9 0.3 2.0 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 RLN88301.1 - 0.00038 19.7 0.1 0.00049 19.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 RLN88301.1 - 0.01 16.4 0.2 0.09 13.3 0.5 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RLN88301.1 - 0.03 13.6 2.3 0.29 10.3 2.0 2.1 1 1 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 RLN88301.1 - 0.037 14.5 0.0 0.056 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 RLN88301.1 - 0.083 12.1 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.6 RLN88302.1 - 1e-08 35.3 0.1 1.5e-08 34.7 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 RLN88302.1 - 4.5e-05 23.9 0.0 0.00011 22.6 0.0 1.5 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 RLN88302.1 - 0.0024 17.1 0.0 0.09 11.9 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 RLN88302.1 - 0.011 15.4 0.1 0.014 15.0 0.1 1.3 1 1 0 1 1 1 0 NmrA-like family KR PF08659.10 RLN88302.1 - 0.015 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 KR domain HIM1 PF08732.10 RLN88302.1 - 0.019 14.5 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 HIM1 Epimerase PF01370.21 RLN88302.1 - 0.054 12.9 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MutS_III PF05192.18 RLN88303.1 - 0.074 13.3 2.2 0.098 12.9 2.2 1.1 1 0 0 1 1 1 0 MutS domain III CCD48 PF15799.5 RLN88303.1 - 0.7 8.1 16.2 0.026 12.8 8.0 1.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 48 Atg14 PF10186.9 RLN88303.1 - 9.5 5.2 10.8 0.77 8.8 2.9 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HNF-1_N PF04814.13 RLN88304.1 - 0.17 12.5 1.8 0.17 12.5 1.8 1.0 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Na_Ca_ex PF01699.24 RLN88305.1 - 1e-50 171.6 37.9 1.1e-28 100.1 16.0 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF2749 PF10907.8 RLN88305.1 - 0.79 9.9 2.9 5.1 7.3 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) DSBA PF01323.20 RLN88307.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Glyco_hydro_1 PF00232.18 RLN88309.1 - 9e-125 416.6 0.0 1.1e-124 416.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 CIDE-N PF02017.15 RLN88309.1 - 0.15 12.1 0.1 8.9 6.4 0.0 2.3 2 0 0 2 2 2 0 CIDE-N domain Whirly PF08536.11 RLN88310.1 - 7.8e-06 25.7 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Whirly transcription factor WD40 PF00400.32 RLN88311.1 - 6.9e-11 42.5 0.2 0.034 15.0 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN88311.1 - 1.8e-09 37.8 0.0 0.073 13.4 0.0 4.0 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 RLN88311.1 - 0.00057 19.3 0.0 0.021 14.1 0.0 2.1 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ PF01011.21 RLN88311.1 - 0.0068 16.3 0.9 6.5 6.9 0.1 3.9 4 0 0 4 4 4 1 PQQ enzyme repeat Nup160 PF11715.8 RLN88311.1 - 0.14 10.8 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Porin_3 PF01459.22 RLN88312.1 - 8e-37 127.2 0.5 8.8e-37 127.0 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin EGF_2 PF07974.13 RLN88313.1 - 1.2e-09 38.3 33.5 6.6e-05 23.2 6.6 3.7 3 0 0 3 3 3 3 EGF-like domain EGF PF00008.27 RLN88313.1 - 0.0062 16.8 34.1 0.064 13.6 6.2 3.8 4 0 0 4 4 4 3 EGF-like domain EB PF01683.18 RLN88313.1 - 0.065 13.5 19.0 0.31 11.3 2.4 3.4 3 0 0 3 3 3 0 EB module hEGF PF12661.7 RLN88313.1 - 8.5 7.2 32.9 3.6 8.4 4.1 4.2 3 0 0 3 3 3 0 Human growth factor-like EGF FMN_red PF03358.15 RLN88314.1 - 0.092 12.5 0.3 0.43 10.3 0.3 1.9 1 1 0 1 1 1 0 NADPH-dependent FMN reductase DUF973 PF06157.11 RLN88314.1 - 0.11 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) EGF_2 PF07974.13 RLN88316.1 - 2.9e-09 37.1 43.6 1.7e-05 25.1 6.3 4.7 4 0 0 4 4 4 4 EGF-like domain EGF PF00008.27 RLN88316.1 - 0.94 9.8 32.5 0.049 14.0 2.4 4.8 4 0 0 4 4 4 0 EGF-like domain Laminin_EGF PF00053.24 RLN88316.1 - 8.6 6.6 36.3 2.8 8.1 10.3 3.9 2 1 1 3 3 3 0 Laminin EGF domain Cyt-b5 PF00173.28 RLN88317.1 - 0.00044 20.4 0.1 0.00069 19.7 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_1 PF00667.20 RLN88318.1 - 0.14 11.7 0.1 21 4.6 0.0 2.5 2 0 0 2 2 2 0 FAD binding domain Mito_carr PF00153.27 RLN88319.1 - 2.2e-56 187.7 3.9 1.2e-19 70.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MaoC_dehydratas PF01575.19 RLN88320.1 - 7.6e-30 103.0 0.0 1.3e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 RLN88320.1 - 9.9e-07 29.0 0.0 6.9e-05 23.0 0.0 2.4 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase WD40 PF00400.32 RLN88321.1 - 2e-11 44.3 0.1 0.17 12.8 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Mucin15 PF15672.5 RLN88321.1 - 0.019 14.5 1.7 0.036 13.5 1.7 1.4 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 DUF2205 PF10224.9 RLN88322.1 - 3.6e-05 23.7 1.9 6e-05 22.9 1.9 1.3 1 0 0 1 1 1 1 Short coiled-coil protein HALZ PF02183.18 RLN88322.1 - 0.002 18.3 0.8 0.14 12.4 0.1 2.5 2 1 0 2 2 2 1 Homeobox associated leucine zipper DUF812 PF05667.11 RLN88322.1 - 0.0025 16.8 4.3 0.0027 16.7 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) YabA PF06156.13 RLN88322.1 - 0.0053 17.4 3.2 0.023 15.3 2.9 2.0 1 1 1 2 2 2 1 Initiation control protein YabA TSC22 PF01166.18 RLN88322.1 - 0.014 15.6 3.8 0.061 13.6 0.3 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family Prp19 PF08606.11 RLN88322.1 - 0.034 14.1 1.3 0.09 12.8 0.2 2.1 1 1 1 2 2 2 0 Prp19/Pso4-like DUF664 PF04978.12 RLN88322.1 - 0.043 14.2 0.7 0.052 13.9 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF664) bZIP_1 PF00170.21 RLN88322.1 - 0.059 13.5 1.5 0.059 13.5 1.5 3.1 2 1 1 3 3 3 0 bZIP transcription factor DUF2218 PF09981.9 RLN88322.1 - 0.077 13.4 0.2 0.095 13.1 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) NRBF2 PF08961.10 RLN88322.1 - 0.13 11.8 4.7 0.72 9.4 4.7 2.0 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator ZapB PF06005.12 RLN88322.1 - 0.17 12.3 7.6 2.2 8.8 7.6 2.3 1 1 0 1 1 1 0 Cell division protein ZapB DOG1 PF14144.6 RLN88322.1 - 0.22 11.8 1.2 0.29 11.4 0.3 1.6 2 0 0 2 2 2 0 Seed dormancy control WDCP PF15390.6 RLN88322.1 - 0.43 8.9 2.7 0.45 8.8 2.7 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family PALP PF00291.25 RLN88323.1 - 1.3e-12 47.8 0.0 1.4e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glutaredoxin PF00462.24 RLN88324.1 - 5.7e-13 48.9 1.5 1.2e-11 44.7 1.5 2.3 1 1 0 1 1 1 1 Glutaredoxin DSBA PF01323.20 RLN88324.1 - 0.013 15.3 0.1 0.04 13.7 0.0 1.7 1 1 1 2 2 2 0 DSBA-like thioredoxin domain GST_N_2 PF13409.6 RLN88324.1 - 0.014 15.7 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain TraF PF13728.6 RLN88324.1 - 0.055 13.3 0.0 0.064 13.1 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 RLN88324.1 - 0.16 12.5 0.2 0.19 12.2 0.2 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain DUF4170 PF13773.6 RLN88324.1 - 0.16 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4170) Pkinase_Tyr PF07714.17 RLN88325.1 - 2.9e-46 157.9 0.0 4e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN88325.1 - 3.5e-46 157.7 0.0 5.1e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 RLN88325.1 - 4.3e-08 32.8 7.2 0.00042 20.0 0.2 4.7 2 1 3 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 RLN88325.1 - 8e-07 29.3 3.2 1.4 9.5 0.1 4.7 2 1 5 7 7 7 5 Leucine Rich repeats (2 copies) FNIP PF05725.12 RLN88325.1 - 0.00075 19.6 4.7 0.08 13.1 0.1 4.0 3 2 1 4 4 4 1 FNIP Repeat Pkinase_fungal PF17667.1 RLN88325.1 - 0.0031 16.4 0.0 0.0072 15.1 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase LRR_6 PF13516.6 RLN88325.1 - 0.0084 16.1 4.6 47 4.4 0.1 5.4 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 RLN88325.1 - 0.018 15.5 1.4 23 6.1 0.0 5.0 4 1 0 4 4 4 0 Leucine Rich Repeat EssA PF10661.9 RLN88325.1 - 0.04 13.7 1.7 0.06 13.2 0.3 2.0 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA DUF1180 PF06679.12 RLN88325.1 - 0.11 12.8 1.7 0.18 12.2 0.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) PX PF00787.24 RLN88326.1 - 5e-09 36.1 0.0 6.6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 PX domain SLATT_fungal PF18142.1 RLN88326.1 - 0.15 12.1 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain TTL PF03133.15 RLN88328.1 - 2.6e-71 240.2 0.1 2.6e-71 240.2 0.1 4.1 5 0 0 5 5 5 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RLN88328.1 - 1.9e-05 24.0 2.2 8.7e-05 21.9 0.0 2.8 3 0 0 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RLN88328.1 - 0.0009 18.6 0.0 0.04 13.1 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp PhoLip_ATPase_C PF16212.5 RLN88329.1 - 1e-59 202.3 21.2 1e-59 202.3 21.2 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RLN88329.1 - 1.1e-20 73.1 0.2 3.3e-20 71.5 0.2 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RLN88329.1 - 1.9e-10 41.4 0.1 0.0017 18.7 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN88329.1 - 1.5e-08 34.6 0.0 4.6e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RLN88329.1 - 7.1e-07 28.9 0.0 2.3e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RLN88329.1 - 0.00019 21.2 0.0 0.00037 20.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase RRM_1 PF00076.22 RLN88330.1 - 3.2e-14 52.5 0.3 2.6e-07 30.4 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RLN88330.1 - 9.3e-07 28.5 0.0 0.034 13.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 RLN88330.1 - 8.8e-06 25.6 0.1 0.00078 19.4 0.1 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 RLN88330.1 - 0.07 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Anthrax-tox_M PF09156.10 RLN88330.1 - 0.18 11.1 0.7 0.27 10.5 0.7 1.1 1 0 0 1 1 1 0 Anthrax toxin lethal factor, middle domain Exonuc_VII_L PF02601.15 RLN88330.1 - 0.67 9.5 4.8 1.1 8.8 4.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit HA2 PF04408.23 RLN88332.1 - 2e-21 76.3 0.1 3.7e-21 75.4 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RLN88332.1 - 3.6e-19 68.9 0.0 6.3e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Rieske_2 PF13806.6 RLN88333.1 - 5.4e-20 71.3 0.0 1.1e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NIR_SIR PF01077.22 RLN88333.1 - 4.5e-15 55.5 0.0 7.2e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 RLN88333.1 - 3.9e-08 33.0 0.0 6.7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.26 RLN88333.1 - 3.9e-07 29.9 0.0 7.1e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain RNA_pol_Rpb2_2 PF04561.14 RLN88334.1 - 1.1e-48 165.4 0.2 1.7e-48 164.7 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_6 PF00562.28 RLN88334.1 - 2e-41 142.4 0.0 3e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 RLN88334.1 - 1.6e-26 92.2 0.0 3.6e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 RLN88334.1 - 2.6e-25 88.5 0.7 5.3e-25 87.5 0.7 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 RLN88334.1 - 3.3e-14 53.2 2.8 8.1e-14 51.9 2.8 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_1 PF04563.15 RLN88334.1 - 5.8e-09 35.7 0.0 8.3e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit Glyco_hydro_30 PF02055.16 RLN88335.1 - 2.6e-104 349.0 4.7 3e-104 348.7 3.9 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 RLN88335.1 - 3.1e-10 40.1 0.0 7.8e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Vps26 PF03643.15 RLN88337.1 - 1.2e-19 70.4 0.0 1.8e-16 59.9 0.0 2.1 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 RLN88337.1 - 0.008 16.2 0.1 0.041 14.0 0.1 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain FYVE PF01363.21 RLN88338.1 - 9.7e-18 64.1 9.1 9.7e-18 64.1 9.1 2.6 2 1 0 2 2 2 1 FYVE zinc finger DEP PF00610.21 RLN88338.1 - 0.0014 18.6 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FYVE_2 PF02318.16 RLN88338.1 - 0.0084 16.3 6.0 0.0084 16.3 6.0 2.4 2 0 0 2 2 2 1 FYVE-type zinc finger PLATZ PF04640.14 RLN88338.1 - 0.062 13.9 1.9 0.062 13.9 1.9 2.6 3 1 0 3 3 3 0 PLATZ transcription factor Peptidase_S24 PF00717.23 RLN88339.1 - 2.6e-09 36.9 0.0 8.9e-09 35.2 0.0 1.8 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 RLN88339.1 - 0.0037 17.0 0.0 3 7.6 0.0 2.9 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_U32_C PF16325.5 RLN88339.1 - 0.14 12.5 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase family U32 C-terminal domain LRR_4 PF12799.7 RLN88340.1 - 6.1e-11 42.4 12.7 7e-06 26.3 5.1 3.7 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN88340.1 - 1.9e-07 30.7 5.4 1.9e-07 30.7 5.4 3.6 3 1 0 3 3 3 1 Leucine rich repeat LRR_9 PF14580.6 RLN88340.1 - 6.9e-05 22.4 7.3 0.042 13.4 0.1 3.7 3 1 0 4 4 4 2 Leucine-rich repeat MAD PF05557.13 RLN88340.1 - 0.0031 15.9 0.5 0.0051 15.3 0.5 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein SecM PF06558.12 RLN88340.1 - 0.0078 16.3 0.0 0.023 14.8 0.0 1.9 1 0 0 1 1 1 1 Secretion monitor precursor protein (SecM) DUF465 PF04325.13 RLN88340.1 - 0.096 12.7 0.7 0.3 11.2 0.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF465) LRR_6 PF13516.6 RLN88340.1 - 0.75 10.0 3.1 29 5.1 0.2 3.3 2 0 0 2 2 2 0 Leucine Rich repeat LRR_1 PF00560.33 RLN88340.1 - 7 7.6 7.9 27 5.8 0.8 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat EF-hand_1 PF00036.32 RLN88341.1 - 4.7e-16 57.1 11.2 0.00045 19.6 0.5 4.8 3 1 1 4 4 4 4 EF hand LRR_6 PF13516.6 RLN88341.1 - 1.4e-15 55.9 17.2 0.0014 18.5 0.3 8.0 8 0 0 8 8 8 4 Leucine Rich repeat EF-hand_7 PF13499.6 RLN88341.1 - 2.3e-14 53.6 6.9 4.6e-07 30.2 1.1 3.5 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN88341.1 - 5e-14 51.0 6.7 0.00013 21.6 0.2 5.0 2 1 2 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 RLN88341.1 - 1.4e-09 37.0 7.6 0.00083 18.8 0.3 4.2 4 0 0 4 4 4 2 EF hand DUF4476 PF14771.6 RLN88341.1 - 4.1e-05 23.8 0.6 0.0016 18.7 0.1 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4476) EF-hand_8 PF13833.6 RLN88341.1 - 9.4e-05 22.2 8.5 0.36 10.7 0.0 4.3 4 0 0 4 4 4 2 EF-hand domain pair LRR_1 PF00560.33 RLN88341.1 - 0.039 14.5 6.7 1.1e+02 4.0 0.2 5.4 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 RLN88341.1 - 0.04 13.7 12.0 1.6 8.6 2.1 4.3 3 1 1 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 RLN88341.1 - 2.5 8.6 11.3 26 5.4 1.2 4.6 2 2 2 5 5 5 0 Leucine Rich repeats (2 copies) TPR_12 PF13424.6 RLN88342.1 - 5.4e-14 52.2 16.5 4.6e-05 23.6 0.4 5.3 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 RLN88342.1 - 6.6e-09 35.3 12.2 0.61 10.4 0.4 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 RLN88342.1 - 2.7e-06 27.0 12.3 0.07 13.2 0.1 6.0 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 RLN88342.1 - 2.8e-05 24.6 12.1 1.6 9.7 0.4 6.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN88342.1 - 0.0001 22.1 15.9 0.79 10.0 0.2 5.9 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN88342.1 - 0.00063 19.5 13.2 0.29 11.0 0.1 6.2 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN88342.1 - 0.0056 16.5 12.2 0.38 10.7 0.1 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 RLN88342.1 - 0.28 11.9 6.0 6.5 7.6 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat polyprenyl_synt PF00348.17 RLN88343.1 - 1.6e-86 289.5 0.0 2.1e-86 289.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CASP_C PF08172.12 RLN88344.1 - 3.4e-61 206.8 0.0 3.4e-61 206.8 0.0 4.4 3 1 1 5 5 5 1 CASP C terminal VGPC1_C PF16799.5 RLN88344.1 - 0.083 12.9 2.3 10 6.2 0.4 3.3 3 0 0 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 DUF2721 PF11026.8 RLN88344.1 - 0.39 10.6 0.0 0.39 10.6 0.0 4.6 5 1 1 6 6 6 0 Protein of unknown function (DUF2721) RRM_1 PF00076.22 RLN88345.1 - 2e-09 37.1 0.0 2.5e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YbjQ_1 PF01906.17 RLN88347.1 - 6.2e-21 75.0 2.6 1.6e-20 73.7 2.6 1.8 1 0 0 1 1 1 1 Putative heavy-metal-binding HemY_N PF07219.13 RLN88347.1 - 0.007 16.6 8.7 0.023 14.9 0.3 3.0 2 0 0 2 2 2 2 HemY protein N-terminus Choline_transpo PF04515.12 RLN88348.1 - 1.3e-88 297.4 33.3 1.3e-88 297.4 33.3 1.9 2 0 0 2 2 2 1 Plasma-membrane choline transporter DUF4207 PF13904.6 RLN88349.1 - 6.9e-05 22.7 36.7 0.00032 20.5 36.7 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4207) GREB1 PF15782.5 RLN88349.1 - 4.4 4.3 10.4 4.7 4.2 10.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PA26 PF04636.13 RLN88349.1 - 5.2 5.9 9.6 6.4 5.6 9.6 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CBFD_NFYB_HMF PF00808.23 RLN88350.1 - 5.9e-23 80.9 1.1 9.2e-23 80.3 1.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 RLN88350.1 - 3.8e-17 62.9 2.3 5.5e-17 62.4 2.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 RLN88350.1 - 0.036 14.4 0.1 0.083 13.2 0.1 1.6 1 0 0 1 1 1 0 CENP-S associating Centromere protein X TPT PF03151.16 RLN88351.1 - 1.3e-36 126.4 17.7 1.2e-35 123.3 17.7 1.9 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 RLN88351.1 - 8.9e-08 32.4 21.2 0.0001 22.5 4.8 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 RLN88351.1 - 1.4e-05 24.4 15.5 3.3e-05 23.3 15.5 1.5 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 RLN88351.1 - 0.21 10.8 17.5 1.3 8.2 17.5 1.8 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Lebercilin PF15619.6 RLN88352.1 - 4.5e-06 26.5 18.6 4.5e-06 26.5 18.6 3.4 2 2 1 3 3 3 2 Ciliary protein causing Leber congenital amaurosis disease Pkinase PF00069.25 RLN88353.1 - 4.2e-50 170.6 0.0 5.4e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN88353.1 - 1e-19 70.9 0.0 1.6e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN88353.1 - 5.1e-06 26.0 0.1 8e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN88353.1 - 0.00021 21.3 0.0 0.0055 16.7 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RLN88353.1 - 0.00098 18.5 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 RLN88353.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Glyco_hydro81C PF17652.1 RLN88354.1 - 6.8e-118 393.9 2.1 9.6e-118 393.4 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 RLN88354.1 - 1.6e-46 158.9 1.2 2.4e-46 158.4 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain LRR_6 PF13516.6 RLN88357.1 - 2.2e-29 99.0 6.0 5e-06 26.1 0.0 7.1 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.7 RLN88357.1 - 6.1e-13 48.7 6.5 0.001 19.4 0.8 5.3 4 1 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN88357.1 - 2.8e-08 33.2 0.0 1.9 9.3 0.1 6.6 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.6 RLN88357.1 - 3.2e-08 33.2 3.2 0.025 14.3 0.5 5.2 3 1 1 4 4 4 2 Leucine rich repeat LRR_2 PF07723.13 RLN88357.1 - 0.044 14.5 0.0 2.2e+02 2.7 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat Imp-YgjV PF10688.9 RLN88358.1 - 0.038 13.8 2.2 0.075 12.8 2.2 1.5 1 1 0 1 1 1 0 Bacterial inner membrane protein TMEM132D_C PF15706.5 RLN88359.1 - 0.0099 15.6 0.1 0.012 15.4 0.1 1.2 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term MtrE PF04206.12 RLN88359.1 - 0.059 12.7 0.2 0.073 12.4 0.2 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit E HA2 PF04408.23 RLN88362.1 - 2.2e-14 53.6 0.0 2.2e-14 53.6 0.0 4.7 4 1 0 4 4 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 RLN88362.1 - 4e-13 49.7 0.1 1.1e-12 48.3 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RLN88362.1 - 2.4e-08 34.0 0.2 1.4e-07 31.4 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 RLN88362.1 - 0.00071 19.9 0.0 0.0032 17.8 0.0 2.2 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 RLN88362.1 - 0.0011 19.3 0.1 0.0011 19.3 0.1 3.5 3 0 0 3 3 3 1 AAA domain DND1_DSRM PF14709.7 RLN88362.1 - 0.011 16.0 0.0 0.045 14.0 0.0 2.2 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Rad17 PF03215.15 RLN88362.1 - 0.07 13.1 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase PF06745.13 RLN88362.1 - 0.078 12.3 0.0 0.27 10.6 0.0 1.9 1 0 0 1 1 1 0 KaiC rRNA_methylase PF06962.12 RLN88362.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative rRNA methylase Zip PF02535.22 RLN88362.1 - 0.18 11.0 1.9 0.46 9.7 1.9 1.7 1 0 0 1 1 1 0 ZIP Zinc transporter dsRBD2 PF17842.1 RLN88362.1 - 0.39 10.9 0.0 0.39 10.9 0.0 2.9 2 1 0 2 2 1 0 Double-stranded RNA binding domain 2 ThrE PF06738.12 RLN88362.1 - 0.86 8.9 6.9 9.2 5.6 5.2 2.5 2 0 0 2 2 2 0 Putative threonine/serine exporter V_ATPase_I PF01496.19 RLN88362.1 - 1.3 6.8 11.4 2.1 6.1 11.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-O PF09496.10 RLN88362.1 - 2.8 7.9 8.6 12 5.8 8.6 2.1 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component Helitron_like_N PF14214.6 RLN88364.1 - 3.7e-11 43.6 0.1 3.7e-11 43.6 0.1 2.4 2 1 0 2 2 2 1 Helitron helicase-like domain at N-terminus Pkinase PF00069.25 RLN88365.1 - 1.1e-52 179.0 0.0 1.6e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN88365.1 - 6.1e-25 88.0 0.0 8.8e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN88365.1 - 4e-06 25.9 0.0 6.3e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 RLN88365.1 - 0.066 12.3 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4922 PF16269.5 RLN88365.1 - 0.085 12.6 0.0 0.3 10.8 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4922) adh_short PF00106.25 RLN88366.1 - 1.4e-34 119.2 3.0 1.7e-33 115.7 3.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN88366.1 - 2.9e-33 115.4 2.0 1.1e-32 113.4 2.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN88366.1 - 0.012 15.6 0.1 0.025 14.5 0.1 1.6 1 0 0 1 1 1 0 KR domain THF_DHG_CYH_C PF02882.19 RLN88366.1 - 0.021 14.1 0.5 0.047 13.0 0.1 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 RLN88366.1 - 0.061 13.4 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 RLN88368.1 - 3.1e-40 137.7 1.6 3.1e-39 134.5 1.6 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN88368.1 - 1.2e-39 136.3 0.9 4.7e-39 134.3 0.9 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN88368.1 - 0.00051 20.0 0.6 0.018 15.0 0.6 2.3 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 RLN88368.1 - 0.0058 16.0 0.2 0.013 14.8 0.0 1.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 RLN88368.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UFD1 PF03152.14 RLN88369.1 - 2.8e-38 131.1 0.0 3.8e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Tautomerase_2 PF14552.6 RLN88370.1 - 0.026 14.6 0.0 0.083 13.0 0.0 1.7 2 0 0 2 2 2 0 Tautomerase enzyme SIR2 PF02146.17 RLN88370.1 - 0.038 13.9 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 Sir2 family adh_short_C2 PF13561.6 RLN88371.1 - 4.3e-32 111.6 3.0 2.3e-27 96.1 1.3 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RLN88371.1 - 1e-30 106.6 2.4 5.3e-19 68.4 0.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 RLN88371.1 - 0.04 13.8 0.6 0.09 12.7 0.1 1.8 2 0 0 2 2 2 0 KR domain Ldh_1_C PF02866.18 RLN88372.1 - 3.3e-48 163.8 0.2 6.5e-48 162.8 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 RLN88372.1 - 2.2e-43 147.8 0.2 3.2e-43 147.2 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 RLN88372.1 - 0.015 14.3 0.0 0.033 13.2 0.0 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 RLN88372.1 - 0.023 14.0 0.2 0.16 11.3 0.1 2.2 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_4 PF02056.16 RLN88372.1 - 0.1 12.2 0.8 0.38 10.3 0.4 2.0 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Semialdhyde_dh PF01118.24 RLN88372.1 - 0.15 12.5 0.3 0.59 10.6 0.1 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain EF-hand_6 PF13405.6 RLN88373.1 - 0.058 13.4 0.5 0.96 9.6 0.1 2.8 3 0 0 3 3 3 0 EF-hand domain MetallophosN PF16371.5 RLN88375.1 - 0.078 13.3 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 N terminal of Calcineurin-like phosphoesterase EF-hand_1 PF00036.32 RLN88376.1 - 4.3e-33 110.4 11.9 1.2e-09 37.0 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RLN88376.1 - 3.7e-29 101.0 6.1 8.7e-15 54.9 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN88376.1 - 1.9e-27 92.8 6.5 6e-10 38.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RLN88376.1 - 2.3e-23 80.6 11.0 1.9e-06 27.1 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 RLN88376.1 - 1.5e-21 76.0 12.1 1.1e-08 34.8 0.4 4.3 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 RLN88376.1 - 6e-10 39.3 0.2 0.00011 22.5 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 RLN88376.1 - 4.6e-07 29.7 4.9 0.023 14.7 0.6 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RLN88376.1 - 5.2e-05 23.5 0.2 0.36 11.2 0.2 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 RLN88376.1 - 9.2e-05 22.7 1.2 0.015 15.6 0.4 2.4 2 1 0 2 2 2 1 EF-hand domain SurA_N_3 PF13624.6 RLN88376.1 - 0.0029 17.4 1.7 0.53 10.1 0.6 2.1 1 1 1 2 2 2 2 SurA N-terminal domain Caleosin PF05042.13 RLN88376.1 - 0.007 16.3 0.2 1.7 8.6 0.0 3.2 2 2 2 4 4 4 1 Caleosin related protein SurA_N_2 PF13623.6 RLN88376.1 - 0.0072 16.2 1.4 0.19 11.6 0.3 2.3 1 1 1 2 2 2 1 SurA N-terminal domain PMBR PF09373.10 RLN88376.1 - 0.017 15.2 0.1 17 5.8 0.0 3.8 3 1 1 4 4 4 0 Pseudomurein-binding repeat FGAR-AT_linker PF18072.1 RLN88376.1 - 0.025 15.1 0.1 2.4 8.7 0.0 2.5 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain SUB1_ProdP9 PF18213.1 RLN88376.1 - 0.042 13.7 0.6 0.12 12.2 0.1 1.8 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 IF2_N PF04760.15 RLN88376.1 - 0.054 13.3 1.6 19 5.2 0.0 3.7 3 1 1 4 4 4 0 Translation initiation factor IF-2, N-terminal region Acetyltransf_11 PF13720.6 RLN88376.1 - 0.088 13.3 0.0 1 9.9 0.0 2.3 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Dockerin_1 PF00404.18 RLN88376.1 - 0.094 12.9 3.0 0.65 10.2 0.2 2.7 2 2 0 2 2 2 0 Dockerin type I domain DUF3008 PF11450.8 RLN88376.1 - 0.28 11.4 0.3 0.28 11.4 0.3 1.9 2 0 0 2 2 1 0 Protein of unknwon function (DUF3008) RrnaAD PF00398.20 RLN88378.1 - 6e-44 150.1 0.0 8.1e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 RLN88378.1 - 4.4e-07 30.5 0.0 1e-06 29.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN88378.1 - 1.2e-05 25.9 0.0 3.5e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN88378.1 - 2.9e-05 23.9 0.0 4.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 RLN88378.1 - 0.0003 20.8 0.0 0.0051 16.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN88378.1 - 0.00037 20.4 0.0 0.0006 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN88378.1 - 0.00095 18.7 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 RLN88378.1 - 0.0016 19.0 0.0 0.0037 17.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 RLN88378.1 - 0.0024 17.6 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_4 PF02390.17 RLN88378.1 - 0.0049 16.3 0.0 0.0087 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase ESX-1_EspG PF14011.6 RLN88378.1 - 0.0076 15.9 0.4 0.0076 15.9 0.4 2.5 3 0 0 3 3 3 1 EspG family Methyltransf_28 PF02636.17 RLN88378.1 - 0.0081 15.8 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.12 RLN88378.1 - 0.032 13.3 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Cation_ATPase_C PF00689.21 RLN88379.1 - 9.6e-37 126.5 1.3 9.6e-37 126.5 1.3 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 RLN88379.1 - 1.5e-30 106.0 12.2 2.6e-21 75.9 0.1 2.9 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 RLN88379.1 - 2.1e-19 69.4 0.0 5.5e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RLN88379.1 - 1.9e-16 61.0 3.6 1.7e-15 57.9 2.4 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 RLN88379.1 - 1.4e-05 25.0 0.0 0.00062 19.6 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RLN88379.1 - 0.0058 16.3 0.0 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 RLN88379.1 - 0.043 14.2 1.1 0.11 12.8 0.2 2.2 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase FliMN_C PF01052.20 RLN88379.1 - 0.11 12.5 0.1 0.28 11.2 0.1 1.7 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term Pardaxin PF07425.11 RLN88379.1 - 1.6 8.4 4.7 0.62 9.7 1.0 2.3 2 0 0 2 2 2 0 Pardaxin WD40 PF00400.32 RLN88380.1 - 1.5e-36 123.7 17.4 3.4e-09 37.2 1.4 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN88380.1 - 1.9e-10 40.9 0.3 0.24 11.7 0.0 6.4 2 1 5 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN88380.1 - 0.0013 17.5 3.1 6 5.4 0.0 3.9 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RLN88380.1 - 0.012 14.6 0.1 9.2 5.1 0.0 3.8 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_3 PF15911.5 RLN88380.1 - 0.096 12.7 0.0 0.45 10.6 0.0 2.1 3 0 0 3 3 3 0 WD domain, G-beta repeat Frtz PF11768.8 RLN88380.1 - 0.12 10.7 0.0 0.2 10.0 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF3844 PF12955.7 RLN88381.1 - 0.049 13.8 0.3 0.11 12.6 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3844) DUF2431 PF10354.9 RLN88382.1 - 9.7e-33 113.8 0.0 1.7e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) zf-C2H2_jaz PF12171.8 RLN88382.1 - 7.2e-12 45.3 18.4 0.011 16.0 0.3 4.9 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 RLN88382.1 - 2.1e-08 34.3 23.8 0.013 16.3 0.9 5.4 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 RLN88382.1 - 2.6e-07 30.7 24.6 0.0058 17.0 0.7 5.5 6 0 0 6 6 5 4 Zinc finger, C2H2 type zf-met PF12874.7 RLN88382.1 - 3.1e-05 24.2 16.9 0.13 12.7 0.2 4.8 5 0 0 5 5 4 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RLN88382.1 - 3.3e-05 23.8 13.9 0.0096 15.9 0.2 4.5 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 RLN88382.1 - 7.5e-05 23.4 1.3 0.00014 22.5 0.5 1.9 1 1 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 RLN88382.1 - 0.00073 19.8 12.9 1.8 9.0 0.2 4.4 2 2 2 4 4 4 2 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.15 RLN88382.1 - 0.0037 17.1 3.2 0.27 11.2 0.1 3.3 3 0 0 3 3 3 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF2256 PF10013.9 RLN88382.1 - 0.0039 17.3 10.5 0.21 11.7 0.1 4.1 3 1 1 4 4 4 2 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_8 PF15909.5 RLN88382.1 - 0.014 15.7 4.1 0.5 10.7 0.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc ribbon zf-met2 PF12907.7 RLN88382.1 - 0.18 12.0 1.8 12 6.1 0.4 2.8 2 0 0 2 2 2 0 Zinc-binding zf_UBZ PF18439.1 RLN88382.1 - 0.62 9.7 11.8 25 4.6 0.4 4.4 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-3CxxC PF13695.6 RLN88382.1 - 0.98 9.9 8.1 8.1 7.0 7.7 2.4 1 1 1 2 2 2 0 Zinc-binding domain Actin_micro PF17003.5 RLN88382.1 - 2.2 7.4 9.0 9.9 5.2 0.2 3.1 2 1 1 3 3 3 0 Putative actin-like family zf_C2H2_ZHX PF18387.1 RLN88382.1 - 2.2 8.0 9.3 0.57 9.9 1.3 3.8 4 1 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain Prok-RING_1 PF14446.6 RLN88382.1 - 2.5 8.1 9.8 33 4.5 0.2 4.4 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 LIM PF00412.22 RLN88382.1 - 4.7 7.5 9.9 46 4.4 0.1 4.1 4 0 0 4 4 4 0 LIM domain Zn-ribbon_8 PF09723.10 RLN88382.1 - 6.1 7.0 15.1 8.4 6.6 0.1 4.7 4 1 0 4 4 4 0 Zinc ribbon domain CBFD_NFYB_HMF PF00808.23 RLN88384.1 - 1.1e-05 25.6 3.9 0.00051 20.3 0.2 3.2 2 1 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SmpB PF01668.18 RLN88384.1 - 0.029 14.3 0.3 0.029 14.3 0.3 2.4 4 0 0 4 4 4 0 SmpB protein PX PF00787.24 RLN88385.1 - 4.2e-18 65.4 0.7 1e-17 64.2 0.7 1.6 1 0 0 1 1 1 1 PX domain APC_N_CC PF16689.5 RLN88385.1 - 0.0011 18.9 0.9 0.0011 18.9 0.9 4.0 3 1 1 4 4 4 1 Coiled-coil N-terminus of APC, dimerisation domain Rop PF01815.16 RLN88385.1 - 0.069 13.0 2.6 0.25 11.3 0.1 2.7 2 0 0 2 2 2 0 Rop protein Nop14 PF04147.12 RLN88386.1 - 0.0055 15.0 8.8 0.0061 14.8 8.8 1.1 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 RLN88386.1 - 0.01 15.2 4.7 0.012 15.0 4.7 1.1 1 0 0 1 1 1 0 BUD22 FmiP_Thoc5 PF09766.9 RLN88386.1 - 0.012 14.9 1.3 0.017 14.5 1.3 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 SDA1 PF05285.12 RLN88386.1 - 0.044 13.2 10.1 0.059 12.8 10.1 1.2 1 0 0 1 1 1 0 SDA1 CPSF100_C PF13299.6 RLN88386.1 - 0.05 13.8 0.9 0.083 13.1 0.9 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Sigma70_ner PF04546.13 RLN88386.1 - 0.057 13.3 10.1 0.092 12.6 10.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3426 PF11906.8 RLN88386.1 - 0.079 13.1 0.7 0.16 12.1 0.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3426) Polyoma_lg_T_C PF06431.11 RLN88386.1 - 0.09 11.6 0.4 0.13 11.1 0.4 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus DUF913 PF06025.12 RLN88386.1 - 0.096 11.6 0.4 0.096 11.7 0.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RXT2_N PF08595.11 RLN88386.1 - 0.12 12.3 3.8 0.19 11.7 3.8 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 RLN88386.1 - 0.14 10.2 17.8 0.2 9.7 17.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 RLN88386.1 - 0.17 10.2 8.1 0.21 9.8 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 RLN88386.1 - 0.24 10.6 6.9 0.32 10.1 6.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 RLN88386.1 - 0.31 10.3 13.9 0.44 9.8 13.9 1.1 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 RLN88386.1 - 0.33 10.6 10.1 0.9 9.2 10.1 1.8 1 1 0 1 1 1 0 FAM176 family PPP4R2 PF09184.11 RLN88386.1 - 0.33 10.5 10.9 0.38 10.3 10.9 1.1 1 0 0 1 1 1 0 PPP4R2 GCIP PF13324.6 RLN88386.1 - 0.37 10.3 5.0 0.51 9.9 5.0 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RRN3 PF05327.11 RLN88386.1 - 0.79 8.2 5.4 0.99 7.9 5.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sporozoite_P67 PF05642.11 RLN88386.1 - 0.96 7.4 5.0 1.2 7.2 5.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TLP-20 PF06088.11 RLN88386.1 - 0.97 9.3 4.2 1.3 8.8 4.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Nop53 PF07767.11 RLN88386.1 - 2.4 7.4 13.0 1.1 8.6 10.7 1.6 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) TFB6 PF17110.5 RLN88386.1 - 3.3 7.4 6.5 5.3 6.8 6.5 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF4637 PF15470.6 RLN88386.1 - 3.8 7.2 12.8 5.6 6.7 12.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Pes-10 PF07149.11 RLN88386.1 - 3.9 6.4 11.4 4.9 6.1 11.4 1.1 1 0 0 1 1 1 0 Pes-10 PTPRCAP PF15713.5 RLN88386.1 - 4.8 7.5 16.9 0.5 10.6 12.5 1.6 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF2457 PF10446.9 RLN88386.1 - 8.4 5.4 17.6 11 5.0 17.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CNDH2_C PF16858.5 RLN88387.1 - 0.0029 17.5 9.0 0.0037 17.2 9.0 1.1 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term zf-RING_UBOX PF13445.6 RLN88388.1 - 5.2e-05 23.2 0.7 0.00013 21.9 0.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN88388.1 - 0.0014 18.5 0.2 0.0044 16.9 0.2 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RLN88388.1 - 0.007 16.2 0.2 0.021 14.7 0.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) EF-hand_1 PF00036.32 RLN88388.1 - 0.012 15.1 0.1 2.3 8.0 0.0 3.7 4 0 0 4 4 4 0 EF hand zf-RING_2 PF13639.6 RLN88388.1 - 0.051 13.9 0.6 0.051 13.9 0.6 2.7 3 1 0 3 3 3 0 Ring finger domain EF-hand_6 PF13405.6 RLN88388.1 - 0.079 12.9 0.0 6.9 6.9 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain Sigma_1s PF02454.16 RLN88389.1 - 0.57 10.2 6.6 0.4 10.7 0.4 2.3 2 0 0 2 2 2 0 Sigma 1s protein MAP65_ASE1 PF03999.12 RLN88389.1 - 8.5 4.9 9.9 13 4.3 9.9 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF5542 PF17696.1 RLN88392.1 - 7 6.9 6.4 1.4 9.1 1.4 2.1 2 1 1 3 3 3 0 Family of unknown function (DUF5542) Pro_isomerase PF00160.21 RLN88393.1 - 9.5e-73 243.7 0.1 9.4e-36 123.5 0.0 2.5 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SpoIIIAH PF12685.7 RLN88393.1 - 1.5e-06 28.2 1.1 3.6e-05 23.7 1.3 2.1 2 0 0 2 2 2 1 SpoIIIAH-like protein Ac76 PF05814.11 RLN88393.1 - 0.032 14.2 0.7 6.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Orf76 (Ac76) Pectate_lyase22 PF14583.6 RLN88393.1 - 0.13 10.9 0.6 0.61 8.7 0.1 1.9 2 0 0 2 2 2 0 Oligogalacturonate lyase TERB2 PF15101.6 RLN88393.1 - 0.29 11.2 2.9 0.78 9.8 2.9 1.7 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PPR PF01535.20 RLN88393.1 - 0.39 11.1 1.3 25 5.4 0.1 2.5 2 0 0 2 2 2 0 PPR repeat TRAP_alpha PF03896.16 RLN88393.1 - 0.85 8.8 4.4 4.8 6.3 3.5 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 RLN88393.1 - 4.7 5.3 12.2 0.45 8.7 8.0 1.4 2 0 0 2 2 2 0 Nop14-like family zf-C2H2 PF00096.26 RLN88394.1 - 5.6e-17 61.2 26.8 4e-05 23.8 1.1 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN88394.1 - 2.6e-14 52.7 23.8 0.0016 19.1 0.9 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RLN88394.1 - 2.1e-10 40.6 23.9 7.6e-07 29.3 0.9 5.4 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_aberr PF17017.5 RLN88394.1 - 6.3e-05 23.2 7.8 0.022 14.9 0.8 3.4 1 1 2 3 3 3 2 Aberrant zinc-finger zf-C2H2_8 PF15909.5 RLN88394.1 - 6.7e-05 23.1 8.1 0.44 10.9 0.1 4.1 2 1 1 4 4 4 2 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 RLN88394.1 - 0.00067 19.4 8.5 0.22 11.3 0.2 3.3 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 RLN88394.1 - 0.00086 19.2 15.3 0.025 14.6 0.3 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RLN88394.1 - 0.00098 19.3 5.8 2.7 8.4 0.2 4.5 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf_Hakai PF18408.1 RLN88394.1 - 0.0028 17.3 2.5 0.16 11.7 0.0 3.4 3 0 0 3 3 3 1 C2H2 Hakai zinc finger domain FOXP-CC PF16159.5 RLN88394.1 - 0.0038 17.8 7.9 0.03 15.0 0.1 3.2 3 1 1 4 4 3 1 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 RLN88394.1 - 0.007 16.1 14.5 0.62 9.9 1.1 4.6 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_9 PF16293.5 RLN88394.1 - 0.043 13.6 4.4 5.5 6.9 0.0 3.9 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) zf_ZIC PF18366.1 RLN88394.1 - 0.1 12.8 4.6 32 4.7 0.0 4.1 3 1 1 4 4 4 0 Zic proteins zinc finger domain zf-BED PF02892.15 RLN88394.1 - 0.15 12.1 4.4 0.17 11.9 0.6 2.6 2 0 0 2 2 2 0 BED zinc finger zf-met PF12874.7 RLN88394.1 - 0.28 11.6 6.4 32 5.1 0.1 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type CHORD PF04968.12 RLN88394.1 - 0.44 11.3 13.8 14 6.5 0.1 4.2 2 2 2 4 4 4 0 CHORD zf-CGNR PF11706.8 RLN88394.1 - 3.2 7.7 5.9 67 3.5 0.0 3.7 4 0 0 4 4 4 0 CGNR zinc finger Zn-C2H2_12 PF18112.1 RLN88394.1 - 6.4 7.3 12.2 55 4.3 2.0 4.7 5 0 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2 PF00096.26 RLN88395.1 - 1.6e-17 62.9 37.8 1.4e-05 25.3 1.7 5.8 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN88395.1 - 3e-17 61.8 29.2 0.00093 19.8 0.8 5.7 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RLN88395.1 - 3.4e-10 39.9 33.8 6.2e-06 26.4 1.6 6.5 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 RLN88395.1 - 3.4e-05 23.7 20.3 0.17 11.9 0.3 5.5 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 RLN88395.1 - 4e-05 23.8 15.6 0.017 15.4 1.3 3.7 2 1 1 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 RLN88395.1 - 7e-05 23.0 11.0 5.9 7.3 0.3 5.4 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 RLN88395.1 - 0.00022 20.9 20.0 0.093 12.5 1.0 5.2 5 0 0 5 5 5 3 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 RLN88395.1 - 0.0097 15.7 20.9 0.37 10.6 0.5 5.0 5 0 0 5 5 5 2 zinc-finger C2H2-type FOXP-CC PF16159.5 RLN88395.1 - 0.27 11.9 0.1 0.27 11.9 0.1 4.3 3 1 2 5 5 4 0 FOXP coiled-coil domain Ogr_Delta PF04606.12 RLN88395.1 - 0.29 11.2 0.1 0.29 11.2 0.1 4.0 3 1 1 4 4 4 0 Ogr/Delta-like zinc finger zf_ZIC PF18366.1 RLN88395.1 - 0.5 10.5 5.0 80 3.5 0.0 4.1 3 2 1 4 4 4 0 Zic proteins zinc finger domain zf-C2H2_aberr PF17017.5 RLN88395.1 - 4.8 7.3 11.6 18 5.5 0.1 3.9 2 1 3 5 5 5 0 Aberrant zinc-finger zf-met PF12874.7 RLN88395.1 - 6.2 7.4 8.5 55 4.3 0.0 5.2 5 0 0 5 5 5 0 Zinc-finger of C2H2 type LRR_6 PF13516.6 RLN88396.1 - 6.1e-09 35.2 0.0 0.0028 17.6 0.0 2.8 2 0 0 2 2 2 2 Leucine Rich repeat DUF4372 PF14294.6 RLN88396.1 - 0.13 12.4 0.6 0.4 10.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4372) DDE_1 PF03184.19 RLN88397.1 - 1.1e-24 87.1 0.1 3.2e-24 85.5 0.1 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.6 RLN88397.1 - 2.7e-14 52.5 0.1 0.0029 17.3 0.0 4.1 3 0 0 3 3 3 3 Homeodomain-like domain CENP-B_N PF04218.13 RLN88397.1 - 1.3e-12 47.1 2.7 0.0042 16.7 0.1 3.7 3 0 0 3 3 3 3 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 RLN88397.1 - 5.6e-12 45.6 4.2 0.0015 18.6 0.0 4.3 4 0 0 4 4 4 3 Helix-turn-helix domain HTH_Tnp_Tc5 PF03221.16 RLN88397.1 - 3.4e-07 30.2 0.0 7.9e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_50 PF18024.1 RLN88397.1 - 7.6e-06 25.4 0.1 4.7 6.9 0.0 3.9 3 1 0 3 3 3 3 Helix-turn-helix domain HTH_Tnp_IS630 PF01710.16 RLN88397.1 - 9.8e-06 25.6 0.1 1.1 9.3 0.1 3.4 3 0 0 3 3 3 2 Transposase HTH_3 PF01381.22 RLN88397.1 - 1.1e-05 25.4 0.1 0.15 12.1 0.0 3.6 3 0 0 3 3 3 1 Helix-turn-helix HTH_29 PF13551.6 RLN88397.1 - 1.6e-05 24.8 0.4 2.3 8.3 0.0 4.0 3 0 0 3 3 3 1 Winged helix-turn helix DUF134 PF02001.16 RLN88397.1 - 2.2e-05 25.0 1.3 0.17 12.5 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function DUF134 Cro PF09048.10 RLN88397.1 - 3.6e-05 23.7 4.3 0.32 11.1 0.1 3.5 3 0 0 3 3 3 2 Cro Sigma70_r4_2 PF08281.12 RLN88397.1 - 4.3e-05 23.1 1.6 2.4 7.9 0.0 4.5 4 0 0 4 4 4 1 Sigma-70, region 4 YdaS_antitoxin PF15943.5 RLN88397.1 - 0.00014 21.6 0.4 0.46 10.4 0.0 3.6 3 0 0 3 3 3 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MarR_2 PF12802.7 RLN88397.1 - 0.00016 21.5 1.0 2.1 8.3 0.0 4.6 4 0 0 4 4 4 1 MarR family HTH_17 PF12728.7 RLN88397.1 - 0.00096 19.3 0.4 0.37 11.0 0.0 3.4 3 0 0 3 3 3 1 Helix-turn-helix domain BrkDBD PF09607.10 RLN88397.1 - 0.0011 18.7 0.0 3 7.7 0.0 3.8 3 0 0 3 3 3 1 Brinker DNA-binding domain HTH_1 PF00126.27 RLN88397.1 - 0.0014 18.5 13.4 0.023 14.6 0.3 4.1 4 0 0 4 4 3 2 Bacterial regulatory helix-turn-helix protein, lysR family HTH_11 PF08279.12 RLN88397.1 - 0.002 18.0 0.4 5.4 7.0 0.0 4.0 3 1 0 3 3 3 1 HTH domain Sigma70_r4 PF04545.16 RLN88397.1 - 0.0021 17.5 0.4 4.8 6.8 0.0 4.4 4 0 0 4 4 4 1 Sigma-70, region 4 KORA PF16509.5 RLN88397.1 - 0.0066 16.7 2.4 4.5 7.6 0.1 3.3 3 0 0 3 3 2 2 TrfB plasmid transcriptional repressor SabA_adhesion PF18304.1 RLN88397.1 - 0.027 13.7 2.9 0.38 9.9 0.3 2.9 3 0 0 3 3 3 0 SabA N-terminal extracellular adhesion domain SpoIIID PF12116.8 RLN88397.1 - 0.029 14.5 1.7 8.6 6.5 0.4 2.8 2 0 0 2 2 2 0 Stage III sporulation protein D AbiEi_4 PF13338.6 RLN88397.1 - 0.052 13.7 0.7 13 6.1 0.0 3.7 4 0 0 4 4 4 0 Transcriptional regulator, AbiEi antitoxin UPF0122 PF04297.14 RLN88397.1 - 0.052 13.8 0.6 21 5.4 0.1 3.4 2 1 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_Tnp_4 PF13613.6 RLN88397.1 - 0.06 13.1 0.0 16 5.3 0.0 3.4 3 0 0 3 3 3 0 Helix-turn-helix of DDE superfamily endonuclease HTH_psq PF05225.16 RLN88397.1 - 0.061 13.1 0.0 15 5.4 0.0 2.7 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_38 PF13936.6 RLN88397.1 - 0.069 12.9 0.0 24 4.8 0.0 3.6 4 0 0 4 4 3 0 Helix-turn-helix domain HTH_24 PF13412.6 RLN88397.1 - 0.14 11.7 0.0 23 4.6 0.0 3.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_8 PF02954.19 RLN88397.1 - 3.4 7.5 6.6 11 5.9 0.0 3.7 4 0 0 4 4 3 0 Bacterial regulatory protein, Fis family Mcm10 PF09332.11 RLN88397.1 - 3.9 6.8 13.8 0.53 9.7 9.3 1.8 2 0 0 2 2 2 0 Mcm10 replication factor DNA_topoisoIV PF00521.20 RLN88398.1 - 1.7e-109 366.5 0.0 2.2e-109 366.2 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 RLN88398.1 - 1.7e-42 144.8 0.0 4.5e-42 143.3 0.0 1.8 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 RLN88398.1 - 4.3e-17 62.1 0.0 4.8e-16 58.7 0.0 2.2 2 0 0 2 2 2 1 DNA gyrase B HATPase_c PF02518.26 RLN88398.1 - 2.2e-09 37.8 0.0 5.6e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 RLN88398.1 - 9.2e-07 29.0 0.0 3.1e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 Toprim domain Glyco_hydro_63 PF03200.16 RLN88399.1 - 2.6e-08 33.1 2.1 2.5e-07 29.9 0.9 2.4 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Trehalase PF01204.18 RLN88399.1 - 0.00052 19.0 7.1 0.0013 17.6 7.1 1.5 1 1 0 1 1 1 1 Trehalase Jacalin PF01419.17 RLN88399.1 - 0.0049 16.8 0.4 0.0093 15.9 0.4 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Beta-prism_lec PF16458.5 RLN88399.1 - 0.03 14.3 0.1 0.078 12.9 0.1 1.7 1 0 0 1 1 1 0 Beta-prism lectin AAA PF00004.29 RLN88400.1 - 5.8e-70 233.8 0.0 4.6e-34 117.7 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RLN88400.1 - 5.4e-13 48.5 14.9 2.2e-07 30.6 0.5 4.6 5 0 0 5 5 5 3 AAA+ lid domain AAA_16 PF13191.6 RLN88400.1 - 2.1e-11 44.5 2.3 0.0019 18.6 0.0 4.1 3 1 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 RLN88400.1 - 3.9e-07 30.2 0.4 0.056 13.4 0.0 3.6 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RLN88400.1 - 1.3e-06 28.6 0.0 0.0001 22.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 RLN88400.1 - 8.6e-06 26.1 0.7 0.00069 19.9 0.1 3.6 2 2 1 3 3 3 1 AAA domain DUF815 PF05673.13 RLN88400.1 - 6e-05 22.3 0.0 0.13 11.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) RuvB_N PF05496.12 RLN88400.1 - 8.3e-05 22.4 0.0 0.31 10.8 0.0 3.5 4 0 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RLN88400.1 - 0.00015 22.0 0.1 0.097 12.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 RLN88400.1 - 0.00029 20.8 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain Vps4_C PF09336.10 RLN88400.1 - 0.00046 20.1 0.0 0.54 10.3 0.0 2.5 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain AAA_7 PF12775.7 RLN88400.1 - 0.0007 19.2 0.0 0.32 10.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 RLN88400.1 - 0.0029 18.0 0.0 2.1 8.8 0.0 3.0 3 0 0 3 3 2 1 RNA helicase IstB_IS21 PF01695.17 RLN88400.1 - 0.0053 16.5 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 RLN88400.1 - 0.012 15.2 0.2 8.6 5.9 0.0 3.3 2 1 1 3 3 3 0 AAA domain TIP49 PF06068.13 RLN88400.1 - 0.012 14.8 0.0 1.8 7.7 0.0 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain Mg_chelatase PF01078.21 RLN88400.1 - 0.02 14.3 0.2 1.1 8.6 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 RLN88400.1 - 0.027 14.4 0.0 0.1 12.5 0.0 2.0 2 1 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 RLN88400.1 - 0.029 14.3 0.0 0.37 10.7 0.0 2.8 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.6 RLN88400.1 - 0.032 14.6 0.1 0.49 10.7 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RLN88400.1 - 0.047 14.2 0.0 0.51 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 RLN88400.1 - 0.05 13.6 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 RLN88400.1 - 0.062 13.0 0.2 1.7 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 RLN88400.1 - 0.078 12.7 0.0 3 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 RLN88400.1 - 0.085 12.6 0.0 1.3 8.7 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 RLN88400.1 - 0.13 12.8 0.0 4.2 7.9 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 RLN88400.1 - 0.14 11.9 0.0 13 5.6 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 RLN88400.1 - 0.2 10.9 0.0 2 7.7 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin Mis12 PF05859.12 RLN88401.1 - 2.6e-09 37.2 1.8 2.6e-09 37.2 1.8 2.1 2 1 0 2 2 2 1 Mis12 protein E2F_CC-MB PF16421.5 RLN88401.1 - 0.061 13.7 6.9 3.2 8.2 1.2 2.8 3 0 0 3 3 3 0 E2F transcription factor CC-MB domain DUF4817 PF16087.5 RLN88401.1 - 0.085 12.7 0.6 1.7 8.5 0.1 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain (DUF4817) RNA12 PF10443.9 RLN88401.1 - 0.1 11.3 6.0 0.12 11.1 5.7 1.3 1 1 0 1 1 1 0 RNA12 protein YabA PF06156.13 RLN88401.1 - 0.55 10.9 12.0 1.1 9.9 7.7 3.0 1 1 1 2 2 2 0 Initiation control protein YabA Tyr_Deacylase PF02580.16 RLN88403.1 - 1.8e-16 61.0 0.0 9.9e-16 58.6 0.0 1.8 1 1 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase AMP-binding PF00501.28 RLN88404.1 - 3.5e-89 299.3 0.0 4.8e-89 298.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN88404.1 - 8.1e-05 23.5 1.0 0.00015 22.7 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Methyltransf_16 PF10294.9 RLN88405.1 - 1.1e-23 83.8 0.0 2.6e-23 82.7 0.0 1.5 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 RLN88405.1 - 2.9e-05 23.7 0.0 4.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 RLN88405.1 - 0.0042 17.8 0.0 0.01 16.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN88405.1 - 0.0079 16.9 0.1 0.014 16.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain EIIA-man PF03610.16 RLN88405.1 - 0.028 14.7 0.0 0.049 13.9 0.0 1.3 1 0 0 1 1 1 0 PTS system fructose IIA component DUF3182 PF11379.8 RLN88405.1 - 0.14 11.1 0.1 0.22 10.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) CTP_transf_like PF01467.26 RLN88406.1 - 1.8e-11 44.4 0.0 2.4e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like UQ_con PF00179.26 RLN88407.1 - 9.8e-11 41.5 0.0 5e-10 39.2 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme LTD PF00932.19 RLN88408.1 - 2.4e-07 31.1 0.0 3.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Lamin Tail Domain Herpes_pp85 PF04637.12 RLN88408.1 - 0.0059 15.1 0.0 0.014 13.9 0.0 1.5 2 0 0 2 2 2 1 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Ank_2 PF12796.7 RLN88409.1 - 1e-42 144.6 3.8 2e-14 53.9 0.1 3.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 RLN88409.1 - 6.8e-41 140.3 0.0 1.2e-40 139.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN88409.1 - 9.5e-38 130.1 0.0 1.7e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 RLN88409.1 - 8.5e-33 112.3 0.4 4.5e-10 39.9 0.0 4.6 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN88409.1 - 2.4e-28 97.3 1.1 6.8e-06 26.3 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 RLN88409.1 - 1e-23 80.8 0.1 0.0006 20.1 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 RLN88409.1 - 2e-21 75.7 3.6 2e-07 31.2 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) NPP1 PF05630.11 RLN88410.1 - 2.4e-67 226.9 0.0 2.7e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) NPP1 PF05630.11 RLN88411.1 - 3.5e-68 229.6 0.0 4.1e-68 229.4 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) NPP1 PF05630.11 RLN88412.1 - 4.5e-77 258.6 0.0 5.3e-77 258.4 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) NPP1 PF05630.11 RLN88413.1 - 1.1e-66 224.7 0.0 1.4e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) NPP1 PF05630.11 RLN88414.1 - 2.9e-67 226.6 0.0 3.3e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) NPP1 PF05630.11 RLN88415.1 - 1.7e-76 256.8 0.0 1.9e-76 256.5 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) C2 PF00168.30 RLN88416.1 - 5.2e-55 184.1 0.0 1.9e-16 60.2 0.0 5.2 5 0 0 5 5 5 4 C2 domain CEP76-C2 PF15627.6 RLN88416.1 - 0.041 13.4 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 CEP76 C2 domain NPP1 PF05630.11 RLN88417.1 - 7.9e-71 238.2 0.0 1.1e-70 237.7 0.0 1.2 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Arrestin_C PF02752.22 RLN88417.1 - 3.6e-13 50.1 0.0 9.5e-09 35.8 0.0 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 RLN88417.1 - 4.7e-09 36.5 0.0 1e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain NPP1 PF05630.11 RLN88418.1 - 5.6e-75 251.8 0.0 6.4e-75 251.6 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) HNF-1B_C PF04812.13 RLN88418.1 - 0.062 13.1 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus Ank_2 PF12796.7 RLN88419.1 - 2.7e-20 72.7 16.6 3.2e-08 34.1 1.0 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN88419.1 - 7.6e-16 58.3 12.4 4.7e-06 27.1 0.2 4.5 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN88419.1 - 5.4e-14 52.1 14.2 0.0093 16.3 0.1 6.6 2 1 5 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN88419.1 - 5.8e-10 38.6 6.3 1.6 9.6 0.1 7.1 5 2 2 7 7 7 2 Ankyrin repeat DUF5049 PF16468.5 RLN88419.1 - 0.00031 20.6 0.5 9.4 6.2 0.0 4.4 1 1 4 5 5 5 2 Domain of unknown function (DUF5049) Ank PF00023.30 RLN88419.1 - 0.0023 18.3 11.5 16 6.2 0.0 6.7 2 1 1 4 4 4 1 Ankyrin repeat HTH_6 PF01418.17 RLN88419.1 - 0.0095 15.9 0.2 0.064 13.2 0.0 2.3 2 1 1 3 3 3 1 Helix-turn-helix domain, rpiR family CHASE PF03924.13 RLN88419.1 - 0.024 14.6 0.0 0.075 13.0 0.0 1.9 2 0 0 2 2 2 0 CHASE domain PH PF00169.29 RLN88420.1 - 2.9e-09 37.4 0.0 7.4e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN88420.1 - 0.00039 20.6 0.6 0.004 17.4 0.6 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.7 RLN88420.1 - 0.0019 18.3 0.0 0.0035 17.5 0.0 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH_11 PF15413.6 RLN88420.1 - 0.0051 17.2 0.1 0.011 16.2 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain zf-C6H2 PF15801.5 RLN88420.1 - 0.01 16.1 7.7 0.01 16.1 7.7 2.9 3 0 0 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding Thioredoxin PF00085.20 RLN88421.1 - 7.9e-21 74.0 0.0 1.7e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Evr1_Alr PF04777.13 RLN88421.1 - 9.7e-20 70.9 1.4 2.3e-19 69.7 1.4 1.6 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin_4 PF13462.6 RLN88421.1 - 0.015 15.5 0.1 0.058 13.5 0.1 2.0 1 0 0 1 1 1 0 Thioredoxin RQC PF09382.10 RLN88421.1 - 0.016 15.0 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 RQC domain Thioredoxin_8 PF13905.6 RLN88421.1 - 0.023 15.0 0.0 0.056 13.8 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like OST3_OST6 PF04756.13 RLN88421.1 - 0.049 13.0 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Zn_Tnp_IS1595 PF12760.7 RLN88421.1 - 0.09 12.8 4.6 1.2 9.2 0.0 3.3 3 0 0 3 3 3 0 Transposase zinc-ribbon domain eIF-5_eIF-2B PF01873.17 RLN88421.1 - 0.15 12.0 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 Domain found in IF2B/IF5 TniQ PF06527.11 RLN88421.1 - 0.16 12.6 2.8 16 6.2 0.1 3.4 3 1 1 4 4 4 0 TniQ Thioredoxin PF00085.20 RLN88422.1 - 1.1e-18 67.1 0.1 2e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Evr1_Alr PF04777.13 RLN88422.1 - 3.4e-16 59.5 1.8 4e-16 59.3 0.1 2.0 2 0 0 2 2 2 1 Erv1 / Alr family OST3_OST6 PF04756.13 RLN88422.1 - 2.4e-06 27.1 0.2 1.1e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 RLN88422.1 - 0.017 15.3 0.3 0.059 13.5 0.1 2.0 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_8 PF13905.6 RLN88422.1 - 0.018 15.4 0.0 0.045 14.1 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.6 RLN88422.1 - 0.074 13.2 0.1 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.6 RLN88422.1 - 0.11 13.0 1.0 0.63 10.5 0.4 2.6 2 1 0 2 2 2 0 Thioredoxin-like domain Zn_Tnp_IS1595 PF12760.7 RLN88422.1 - 0.16 12.0 3.6 3.5 7.7 0.0 3.2 3 0 0 3 3 3 0 Transposase zinc-ribbon domain AhpC-TSA PF00578.21 RLN88422.1 - 0.25 11.3 0.6 2.2 8.2 0.1 2.7 3 1 0 3 3 3 0 AhpC/TSA family Glyco_hydro_1 PF00232.18 RLN88423.1 - 3.8e-61 206.9 0.5 4.3e-61 206.7 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 RLN88423.1 - 0.011 15.2 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Thioredoxin PF00085.20 RLN88424.1 - 8.6e-24 83.5 0.7 2e-23 82.3 0.7 1.7 1 0 0 1 1 1 1 Thioredoxin Evr1_Alr PF04777.13 RLN88424.1 - 2.4e-17 63.3 0.2 7.7e-17 61.6 0.2 2.0 1 0 0 1 1 1 1 Erv1 / Alr family OST3_OST6 PF04756.13 RLN88424.1 - 6.7e-05 22.4 0.2 6.7e-05 22.4 0.2 1.9 3 0 0 3 3 3 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 RLN88424.1 - 0.00068 19.9 0.3 0.0035 17.6 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.6 RLN88424.1 - 0.0019 18.4 0.1 0.0063 16.7 0.1 1.9 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 RLN88424.1 - 0.036 14.0 0.1 0.15 12.0 0.1 2.1 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_9 PF14595.6 RLN88424.1 - 0.04 13.7 0.1 0.11 12.2 0.1 1.8 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.10 RLN88424.1 - 0.044 13.5 0.2 0.094 12.4 0.2 1.5 1 0 0 1 1 1 0 Redoxin Thioredoxin_4 PF13462.6 RLN88424.1 - 0.11 12.7 4.7 0.18 12.0 2.1 2.6 1 1 1 2 2 2 0 Thioredoxin Zn_Tnp_IS1595 PF12760.7 RLN88424.1 - 0.2 11.6 3.6 7.2 6.7 0.0 3.4 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 RLN88424.1 - 0.38 10.9 3.6 28 4.9 0.1 3.4 3 0 0 3 3 3 0 Zinc ribbon domain zf-RING_2 PF13639.6 RLN88425.1 - 5e-12 46.0 9.2 5e-12 46.0 9.2 2.4 3 0 0 3 3 2 1 Ring finger domain PX PF00787.24 RLN88425.1 - 5.2e-09 36.1 0.0 9e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 PX domain zf-rbx1 PF12678.7 RLN88425.1 - 5.6e-08 32.9 13.9 7.9e-08 32.5 11.2 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RLN88425.1 - 6.6e-07 29.1 6.9 6.6e-07 29.1 6.9 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN88425.1 - 7.9e-07 29.0 6.3 7.9e-07 29.0 6.3 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 RLN88425.1 - 1.8e-06 27.6 6.0 1.8e-06 27.6 6.0 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 RLN88425.1 - 4.4e-06 26.5 6.3 4.4e-06 26.5 6.3 2.7 2 1 1 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RLN88425.1 - 1.1e-05 25.2 1.9 1.1e-05 25.2 1.9 2.9 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 RLN88425.1 - 1.2e-05 25.2 5.8 1.2e-05 25.2 5.8 2.0 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RLN88425.1 - 0.00012 21.9 5.8 0.00012 21.9 5.8 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN88425.1 - 0.00019 21.2 13.9 0.00026 20.8 10.7 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 RLN88425.1 - 0.017 14.8 5.6 0.017 14.8 5.6 2.9 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 RLN88425.1 - 0.33 11.2 8.5 1.3 9.3 8.5 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 RLN88425.1 - 0.5 10.5 8.2 2.3 8.4 8.2 2.2 1 0 0 1 1 1 0 RING-variant domain M16C_assoc PF08367.11 RLN88426.1 - 4.8e-15 55.4 0.1 6.9e-15 54.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase M16C associated PC_rep PF01851.22 RLN88426.1 - 0.053 14.0 0.0 0.43 11.1 0.0 2.6 2 0 0 2 2 2 0 Proteasome/cyclosome repeat Alpha_kinase PF02816.18 RLN88427.1 - 1.1e-53 182.1 0.0 1.6e-53 181.6 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family SHOCT PF09851.9 RLN88427.1 - 0.00043 19.9 0.0 0.00079 19.1 0.0 1.5 1 0 0 1 1 1 1 Short C-terminal domain Glycos_transf_1 PF00534.20 RLN88428.1 - 5.2e-37 127.0 0.0 9.9e-37 126.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RLN88428.1 - 6.9e-20 71.8 0.1 2.1e-19 70.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 RLN88428.1 - 4.4e-11 43.1 0.2 8.2e-11 42.2 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 RLN88428.1 - 6.8e-07 29.6 0.0 1.5e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 RLN88428.1 - 0.00011 22.7 1.6 0.00015 22.3 0.2 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyphos_transf PF04464.14 RLN88428.1 - 0.041 12.9 0.1 0.085 11.8 0.0 1.5 2 0 0 2 2 2 0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Myotub-related PF06602.14 RLN88429.1 - 3.2e-126 421.0 0.0 4.5e-126 420.5 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain RabGAP-TBC PF00566.18 RLN88429.1 - 2.9e-28 99.0 0.0 6.8e-14 52.0 0.1 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PDZ PF00595.24 RLN88429.1 - 0.00092 19.5 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RLN88429.1 - 0.018 14.9 0.1 0.045 13.6 0.1 1.6 1 0 0 1 1 1 0 PDZ domain Y_phosphatase3 PF13350.6 RLN88429.1 - 0.081 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family GRAM PF02893.20 RLN88429.1 - 0.09 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 GRAM domain Ketoacyl-synt_C PF02801.22 RLN88430.1 - 4.7e-23 81.5 0.1 8.3e-23 80.6 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 RLN88430.1 - 5.1e-12 45.9 0.1 2.6e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain KAsynt_C_assoc PF16197.5 RLN88430.1 - 0.18 12.3 0.0 0.42 11.1 0.0 1.7 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension IFT57 PF10498.9 RLN88431.1 - 0.0063 15.5 9.3 0.0063 15.5 9.3 4.2 3 1 1 4 4 4 2 Intra-flagellar transport protein 57 Tropomyosin_1 PF12718.7 RLN88431.1 - 0.012 15.8 4.1 0.012 15.8 4.1 6.8 2 2 4 7 7 7 0 Tropomyosin like Csm1_N PF18504.1 RLN88431.1 - 0.044 14.1 1.0 0.044 14.1 1.0 10.0 8 3 4 12 12 12 0 Csm1 N-terminal domain DUF1652 PF07865.11 RLN88431.1 - 0.044 13.6 0.2 0.14 12.0 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) PKcGMP_CC PF16808.5 RLN88431.1 - 6.7 6.7 18.3 1.2 9.0 0.4 5.7 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PhetRS_B1 PF18262.1 RLN88432.1 - 7.5e-36 122.2 0.0 9.8e-36 121.8 0.0 1.1 1 0 0 1 1 1 1 Phe-tRNA synthetase beta subunit B1 domain Ank_2 PF12796.7 RLN88433.1 - 2.7e-23 82.4 4.4 1.4e-11 44.8 1.1 3.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN88433.1 - 4.2e-18 63.6 0.9 0.00088 19.5 0.1 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 RLN88433.1 - 8.7e-16 57.8 4.6 9.8e-06 25.8 0.1 4.7 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN88433.1 - 9.8e-16 57.9 0.3 6.2e-09 36.2 0.2 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN88433.1 - 1.5e-14 53.7 0.8 1e-05 25.8 0.3 4.7 4 0 0 4 4 4 3 Ankyrin repeat AAA_23 PF13476.6 RLN88433.1 - 0.19 12.2 2.7 0.33 11.4 2.7 1.4 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 RLN88433.1 - 0.4 9.5 12.5 0.62 8.9 12.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Csm1_N PF18504.1 RLN88433.1 - 0.41 11.0 12.6 2.1 8.8 1.2 2.8 2 0 0 2 2 2 0 Csm1 N-terminal domain SlyX PF04102.12 RLN88433.1 - 2.9 8.6 11.9 0.79 10.4 5.8 2.8 1 1 1 2 2 2 0 SlyX Sec2p PF06428.11 RLN88433.1 - 7.6 6.6 16.2 0.17 11.9 3.6 2.8 1 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Asp PF00026.23 RLN88434.1 - 2.8e-16 59.8 0.2 3.7e-16 59.4 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RLN88434.1 - 3.6e-05 24.1 0.2 5.3e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 RLN88434.1 - 0.0039 17.0 0.0 0.0087 15.9 0.0 1.7 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 RLN88435.1 - 1e-23 84.5 3.4 1.8e-23 83.7 3.4 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 RLN88435.1 - 2.1e-23 83.3 1.4 4.3e-23 82.2 1.4 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 RLN88435.1 - 2e-10 40.7 0.0 3.6e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TMEM154 PF15102.6 RLN88435.1 - 0.024 14.6 2.8 0.071 13.0 2.8 1.7 1 1 0 1 1 1 0 TMEM154 protein family Amnionless PF14828.6 RLN88435.1 - 0.033 13.0 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Amnionless MAP17 PF15807.5 RLN88435.1 - 0.073 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 HIG_1_N PF04588.13 RLN88435.1 - 0.084 13.1 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Hypoxia induced protein conserved region FAM176 PF14851.6 RLN88435.1 - 0.36 10.5 4.5 0.71 9.5 3.7 1.8 1 1 1 2 2 2 0 FAM176 family DUF1191 PF06697.12 RLN88436.1 - 0.01 15.7 0.1 0.53 10.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) ANAPC4_WD40 PF12894.7 RLN88436.1 - 0.063 13.6 0.0 3.6 8.0 0.0 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-B_box PF00643.24 RLN88438.1 - 1.1e-14 54.2 15.8 9.9e-08 32.0 1.4 2.4 2 0 0 2 2 2 2 B-box zinc finger PARP PF00644.20 RLN88438.1 - 0.0048 16.5 0.0 0.0099 15.5 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain CEBP_ZZ PF16366.5 RLN88438.1 - 0.014 15.6 9.3 0.073 13.3 4.1 2.4 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain IBR PF01485.21 RLN88438.1 - 0.059 13.6 9.1 0.07 13.4 1.5 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Eapp_C PF10238.9 RLN88438.1 - 0.7 10.0 4.5 2.7 8.1 0.6 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF3160 PF11369.8 RLN88439.1 - 5.8e-112 375.2 0.0 6e-111 371.9 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3160) B9-C2 PF07162.11 RLN88440.1 - 2e-21 76.9 0.0 3e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein NAD_binding_10 PF13460.6 RLN88441.1 - 3.9e-18 66.0 0.0 5.9e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 RLN88441.1 - 5.7e-13 48.5 0.0 3.9e-12 45.8 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 RLN88441.1 - 1.8e-08 34.2 0.0 3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 RLN88441.1 - 2.2e-08 33.9 0.1 3.6e-08 33.2 0.1 1.3 1 1 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 RLN88441.1 - 0.00087 18.8 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 RLN88441.1 - 0.015 14.4 0.1 0.033 13.3 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain EF-hand_1 PF00036.32 RLN88442.1 - 1.7e-32 108.5 17.2 3.8e-09 35.5 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RLN88442.1 - 1e-29 102.7 10.3 2.9e-16 59.7 0.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN88442.1 - 1.5e-25 86.9 12.0 1.6e-09 37.0 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 RLN88442.1 - 2.9e-24 84.7 14.7 1.4e-12 47.2 1.0 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 RLN88442.1 - 1.1e-15 56.3 16.3 1.2e-05 24.5 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 RLN88442.1 - 1.1e-14 54.5 0.4 5.4e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 RLN88442.1 - 0.00024 21.0 11.9 1.5 8.9 1.5 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 RLN88442.1 - 0.00025 21.3 1.2 0.29 11.5 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain Caleosin PF05042.13 RLN88442.1 - 0.0014 18.6 1.4 2.5 8.0 0.0 3.7 1 1 3 4 4 4 1 Caleosin related protein SurA_N_2 PF13623.6 RLN88442.1 - 0.005 16.7 0.6 0.57 10.0 0.0 2.4 1 1 0 2 2 2 1 SurA N-terminal domain TerB PF05099.13 RLN88442.1 - 0.011 15.7 1.0 0.078 12.9 0.1 2.3 1 1 0 2 2 2 0 Tellurite resistance protein TerB SurA_N_3 PF13624.6 RLN88442.1 - 0.014 15.2 0.4 0.11 12.3 0.1 2.0 1 1 1 2 2 2 0 SurA N-terminal domain Ribosomal_S3Ae PF01015.18 RLN88442.1 - 0.017 14.7 0.1 0.027 14.0 0.1 1.3 1 0 0 1 1 1 0 Ribosomal S3Ae family EF-hand_11 PF08976.11 RLN88442.1 - 0.019 15.8 0.3 0.23 12.3 0.1 2.1 1 1 1 2 2 2 0 EF-hand domain ERAP1_C PF11838.8 RLN88442.1 - 0.039 13.5 0.0 0.053 13.1 0.0 1.1 1 0 0 1 1 1 0 ERAP1-like C-terminal domain TFIIS_M PF07500.14 RLN88442.1 - 0.058 13.9 0.8 0.14 12.7 0.1 1.9 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain SUB1_ProdP9 PF18213.1 RLN88442.1 - 0.07 13.0 1.3 0.29 11.0 0.1 2.1 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 Glyco_transf_92 PF01697.27 RLN88442.1 - 0.072 12.7 0.2 0.099 12.3 0.2 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 92 DUF5126 PF17166.4 RLN88442.1 - 0.14 12.0 0.0 16 5.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5126) MerR-DNA-bind PF09278.11 RLN88442.1 - 0.19 12.3 1.9 5.2 7.7 0.1 3.3 3 1 1 4 4 4 0 MerR, DNA binding MgtE_N PF03448.17 RLN88442.1 - 0.33 11.6 3.7 4 8.1 0.2 3.0 2 1 1 3 3 3 0 MgtE intracellular N domain Arc_PepC PF06819.11 RLN88442.1 - 0.56 10.3 4.9 0.13 12.3 1.4 1.8 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain GATase PF00117.28 RLN88443.1 - 2.8e-44 151.2 0.0 3.3e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 RLN88443.1 - 0.0081 15.9 0.4 0.096 12.4 0.4 2.3 1 1 0 1 1 1 1 Peptidase C26 DUF2371 PF10177.9 RLN88444.1 - 0.085 13.0 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) SPX PF03105.19 RLN88445.1 - 4.6e-09 36.7 28.2 0.00016 21.7 0.2 4.8 2 1 2 4 4 4 4 SPX domain NEMO PF11577.8 RLN88446.1 - 0.036 14.1 0.0 0.086 12.9 0.0 1.6 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO TPR_MLP1_2 PF07926.12 RLN88446.1 - 0.26 11.3 4.5 0.86 9.7 4.5 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ABATE PF07336.11 RLN88446.1 - 0.33 11.6 6.4 0.36 11.5 5.9 1.4 1 1 0 1 1 1 0 Putative stress-induced transcription regulator Dicer_dimer PF03368.14 RLN88447.1 - 0.11 12.7 0.4 0.56 10.4 0.4 2.3 1 0 0 1 1 1 0 Dicer dimerisation domain Cyclin_N2 PF16500.5 RLN88447.1 - 4.3 8.1 9.3 1.5 9.5 3.2 2.5 1 1 1 2 2 2 0 N-terminal region of cyclin_N DUF667 PF05018.13 RLN88448.1 - 3.8e-28 98.5 0.0 7.7e-28 97.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF667) KAR9 PF08580.10 RLN88450.1 - 7.9 4.9 8.0 10 4.5 8.0 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 UCH PF00443.29 RLN88451.1 - 3.2e-25 89.1 0.4 5.3e-25 88.4 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 RLN88451.1 - 4.5e-14 52.5 1.6 8e-14 51.7 1.6 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 RLN88451.1 - 0.0027 17.4 0.7 0.0099 15.5 0.1 2.2 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase HyaE PF07449.11 RLN88451.1 - 0.11 12.5 0.0 0.96 9.4 0.0 2.2 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE zf-UBP_var PF17807.1 RLN88451.1 - 0.12 12.2 0.3 0.25 11.1 0.3 1.4 1 0 0 1 1 1 0 Variant UBP zinc finger MIT PF04212.18 RLN88452.1 - 2.9e-13 49.7 6.4 7.5e-13 48.3 6.4 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 RLN88452.1 - 1.1e-10 41.1 0.3 2e-09 37.1 0.1 2.6 2 1 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 RLN88452.1 - 1.1e-09 38.8 0.0 2.9e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN88452.1 - 7.2e-08 33.0 4.2 2.5e-07 31.2 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 RLN88452.1 - 0.0001 22.9 0.1 0.021 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Vps4_C PF09336.10 RLN88452.1 - 0.00024 21.0 0.0 0.00058 19.8 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 RLN88452.1 - 0.00038 20.7 0.1 0.0015 18.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RLN88452.1 - 0.00051 19.8 0.1 0.0012 18.6 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.12 RLN88452.1 - 0.0011 18.8 0.0 0.0029 17.4 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RLN88452.1 - 0.0011 18.9 0.2 0.0035 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 RLN88452.1 - 0.0039 17.6 0.0 0.0082 16.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 RLN88452.1 - 0.0039 16.6 0.0 0.0079 15.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 RLN88452.1 - 0.0052 16.2 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein NACHT PF05729.12 RLN88452.1 - 0.0063 16.4 0.1 0.017 15.1 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 RLN88452.1 - 0.0077 16.4 0.4 0.026 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RLN88452.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TIP49 PF06068.13 RLN88452.1 - 0.014 14.6 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 RLN88452.1 - 0.021 14.5 0.1 0.055 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 RLN88452.1 - 0.025 14.2 1.1 0.043 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 RLN88452.1 - 0.039 13.7 3.9 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RLN88452.1 - 0.041 14.1 0.0 0.041 14.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain Use1 PF09753.9 RLN88452.1 - 0.068 12.9 3.9 0.11 12.3 3.9 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 ABC_tran PF00005.27 RLN88452.1 - 0.12 12.8 0.1 0.7 10.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_17 PF13207.6 RLN88452.1 - 0.19 12.1 0.7 1.6 9.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF5327 PF17261.2 RLN88452.1 - 0.22 12.3 3.1 0.45 11.3 3.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5327) EFP_N PF08207.12 RLN88453.1 - 3.8e-21 74.9 0.3 9.9e-21 73.5 0.3 1.8 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Elong-fact-P_C PF09285.11 RLN88453.1 - 1.5e-13 50.2 0.3 3.7e-13 49.0 0.3 1.6 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP PF01132.20 RLN88453.1 - 1.1e-12 47.8 0.6 1.7e-12 47.1 0.2 1.6 2 0 0 2 2 2 1 Elongation factor P (EF-P) OB domain E1_dh PF00676.20 RLN88454.1 - 8e-103 343.5 0.2 1e-102 343.1 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 RLN88454.1 - 0.0058 15.9 0.4 0.01 15.1 0.1 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.21 RLN88454.1 - 0.077 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Endosulfine PF04667.17 RLN88455.1 - 1e-06 28.7 2.2 0.0075 16.4 0.2 2.4 1 1 0 2 2 2 2 cAMP-regulated phosphoprotein/endosulfine conserved region DUF5546 PF17700.1 RLN88455.1 - 0.037 14.4 0.6 0.063 13.6 0.6 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5546) PP2C PF00481.21 RLN88456.1 - 3.7e-49 167.7 0.0 4.6e-46 157.5 0.0 2.3 1 1 1 2 2 2 2 Protein phosphatase 2C ACCA PF03255.14 RLN88456.1 - 0.18 11.7 2.9 0.27 11.1 2.2 1.7 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF3967 PF13152.6 RLN88456.1 - 0.49 10.2 2.7 1.2 8.9 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3967) TMF_TATA_bd PF12325.8 RLN88456.1 - 8.5 6.6 12.8 2 8.6 8.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding T2SSM PF04612.12 RLN88457.1 - 0.027 14.5 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DUF3357 PF11837.8 RLN88457.1 - 0.035 14.5 1.2 0.044 14.2 0.3 1.6 1 1 0 2 2 2 0 Domain of unknown function (DUF3357) DUF4307 PF14155.6 RLN88457.1 - 0.058 13.2 0.1 0.092 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) DUF3328 PF11807.8 RLN88457.1 - 0.07 12.9 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Sigma_reg_N PF13800.6 RLN88457.1 - 0.22 11.8 0.0 0.3 11.4 0.0 1.1 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Peptidase_S10 PF00450.22 RLN88458.1 - 7.8e-110 368.1 0.1 9.7e-110 367.8 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 RLN88459.1 - 1.9e-116 390.0 0.0 2.2e-116 389.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 RLN88459.1 - 0.0024 18.5 0.4 0.76 10.3 0.0 2.7 3 0 0 3 3 3 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 RLN88459.1 - 0.14 11.6 0.0 4.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Peptidase_S10 PF00450.22 RLN88460.1 - 1.9e-110 370.1 0.2 2.4e-110 369.8 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Pilin_N PF07790.11 RLN88460.1 - 0.088 13.7 0.1 0.23 12.4 0.1 1.6 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal Peptidase_S10 PF00450.22 RLN88461.1 - 1.6e-106 357.3 0.2 2.6e-106 356.5 0.2 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 RLN88461.1 - 3.6e-05 24.5 0.1 0.0079 16.8 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF2811 PF10929.8 RLN88461.1 - 0.022 15.0 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) Peptidase_S10 PF00450.22 RLN88462.1 - 3e-116 389.3 0.6 3.8e-116 388.9 0.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 RLN88462.1 - 0.035 14.7 0.0 0.24 12.0 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family HELP PF03451.14 RLN88463.1 - 3.3e-35 119.8 5.0 2.1e-16 59.5 0.0 4.0 4 0 0 4 4 4 3 HELP motif WD40 PF00400.32 RLN88463.1 - 1.6e-31 107.9 79.3 0.018 15.9 0.2 27.0 31 0 0 31 31 31 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN88463.1 - 2.4e-25 88.7 0.0 0.023 15.0 0.0 13.0 11 3 4 15 15 15 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN88463.1 - 1.5e-06 27.4 0.7 1 8.2 0.0 5.1 5 0 0 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 RLN88463.1 - 0.00083 19.2 2.3 6.7 6.8 0.0 5.5 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 RLN88463.1 - 0.00099 17.7 0.0 0.025 13.1 0.0 3.0 3 0 0 3 3 3 1 Cytochrome D1 heme domain Nup160 PF11715.8 RLN88463.1 - 0.071 11.8 0.0 6.3 5.3 0.0 3.3 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Mcl1_mid PF12341.8 RLN88463.1 - 0.26 10.6 0.8 0.68 9.2 0.1 2.1 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region Dioxygenase_C PF00775.21 RLN88464.1 - 2.1e-08 33.8 0.0 4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase NOZZLE PF08744.10 RLN88464.1 - 0.0027 17.2 0.6 0.0046 16.5 0.6 1.3 1 0 0 1 1 1 1 Plant transcription factor NOZZLE Yippee-Mis18 PF03226.14 RLN88465.1 - 3.3e-05 24.0 1.7 0.00017 21.8 1.7 2.1 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2H2_3rep PF18868.1 RLN88465.1 - 0.0079 16.9 0.0 0.014 16.0 0.0 1.4 1 0 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats RRM_1 PF00076.22 RLN88466.1 - 2.8e-26 91.1 0.1 3.6e-09 36.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RLN88466.1 - 0.0036 17.1 0.0 0.53 10.2 0.0 2.7 2 0 0 2 2 2 2 Occluded RNA-recognition motif Calcipressin PF04847.12 RLN88466.1 - 0.027 14.2 0.2 0.15 11.7 0.0 2.3 3 0 0 3 3 3 0 Calcipressin RRM_5 PF13893.6 RLN88466.1 - 0.08 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FYVE PF01363.21 RLN88467.1 - 7.9e-11 41.9 10.1 7.9e-11 41.9 10.1 2.1 2 0 0 2 2 2 1 FYVE zinc finger SAPS PF04499.15 RLN88467.1 - 0.014 14.2 0.0 0.014 14.2 0.0 2.8 3 0 0 3 3 3 0 SIT4 phosphatase-associated protein PH PF00169.29 RLN88467.1 - 0.028 14.9 0.9 1.2 9.7 0.0 3.1 3 0 0 3 3 3 0 PH domain IBR PF01485.21 RLN88467.1 - 0.43 10.9 8.1 1.4 9.2 8.1 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain FYVE_2 PF02318.16 RLN88467.1 - 0.54 10.5 5.4 2 8.6 5.4 2.0 1 0 0 1 1 1 0 FYVE-type zinc finger TBCC PF07986.12 RLN88468.1 - 4.2e-25 87.8 4.7 5.4e-25 87.5 4.7 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 RLN88468.1 - 1.2e-05 25.0 0.9 1.6e-05 24.6 0.9 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Spt4 PF06093.13 RLN88468.1 - 0.018 15.1 0.9 0.018 15.1 0.9 3.0 2 1 0 3 3 3 0 Spt4/RpoE2 zinc finger Coat_X PF07552.11 RLN88468.1 - 0.1 12.4 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Spore Coat Protein X and V domain Cyclin_N PF00134.23 RLN88469.1 - 8.4e-26 90.2 0.6 6.5e-24 84.1 0.1 3.0 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 RLN88469.1 - 5.5e-19 68.4 0.7 5.5e-19 68.4 0.7 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain DnaJ PF00226.31 RLN88470.1 - 1.2e-22 79.8 0.1 2.4e-22 78.8 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 RLN88470.1 - 3e-14 53.3 0.1 8.7e-11 42.1 0.1 2.3 1 1 1 2 2 2 2 DnaJ C terminal domain Pkinase PF00069.25 RLN88472.1 - 2.1e-66 224.0 0.0 3.8e-66 223.1 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN88472.1 - 2.1e-47 161.6 0.0 3.1e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN88472.1 - 2.3e-05 23.4 0.0 3.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN88472.1 - 0.00029 20.3 0.1 0.00091 18.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 RLN88472.1 - 0.004 17.1 0.5 0.12 12.2 0.0 2.9 3 1 1 4 4 4 2 Phosphotransferase enzyme family Kdo PF06293.14 RLN88472.1 - 0.028 13.8 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 RLN88472.1 - 0.08 13.1 1.6 0.13 12.5 0.0 2.2 3 0 0 3 3 3 0 ABC1 family 2-oxoacid_dh PF00198.23 RLN88473.1 - 1.8e-68 230.5 0.0 2.4e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 RLN88473.1 - 7.3e-14 51.4 0.0 1.5e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 RLN88473.1 - 0.071 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like S36_mt PF10937.8 RLN88473.1 - 0.12 14.0 0.1 0.12 14.0 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein S36, mitochondrial Ribosomal_60s PF00428.19 RLN88473.1 - 0.61 10.7 13.5 1.8 9.2 3.0 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein IFT81_CH PF18383.1 RLN88475.1 - 1.8e-29 102.5 0.0 5.2e-29 101.0 0.0 1.9 1 0 0 1 1 1 1 Intraflagellar transport 81 calponin homology domain BLOC1_2 PF10046.9 RLN88475.1 - 0.01 16.1 26.4 0.087 13.1 0.3 6.1 5 1 1 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tup_N PF08581.10 RLN88475.1 - 0.016 15.5 4.4 0.016 15.5 4.4 5.4 5 1 0 5 5 5 0 Tup N-terminal NPV_P10 PF05531.12 RLN88475.1 - 0.17 12.3 11.5 6.6 7.3 0.1 5.3 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 RLN88475.1 - 1.6 8.8 23.3 3.2 7.8 0.6 5.3 6 0 0 6 6 6 0 Protein of unknown function (DUF1664) Acyl-CoA_dh_C PF12806.7 RLN88475.1 - 4.9 7.3 8.6 1.8 8.7 0.1 4.1 4 1 0 4 4 4 0 Acetyl-CoA dehydrogenase C-terminal like Rep_fac-A_3 PF08661.11 RLN88477.1 - 2.4e-17 63.2 0.0 3.7e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Replication factor A protein 3 PilP PF04351.13 RLN88477.1 - 0.0084 16.1 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Pilus assembly protein, PilP RsgI_N PF12791.7 RLN88477.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Anti-sigma factor N-terminus Amidohydro_3 PF07969.11 RLN88478.1 - 6.8e-76 256.6 0.1 9.9e-76 256.1 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 RLN88478.1 - 4.1e-11 42.8 0.0 1.9e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family PB1 PF00564.24 RLN88478.1 - 0.022 14.7 0.0 0.061 13.3 0.0 1.7 1 0 0 1 1 1 0 PB1 domain Spidroin_N PF16763.5 RLN88480.1 - 0.036 14.1 8.7 0.045 13.8 8.7 1.2 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term TetR_C_20 PF17925.1 RLN88480.1 - 0.19 12.0 8.3 0.22 11.8 8.3 1.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain APG6_N PF17675.1 RLN88480.1 - 0.58 10.7 11.5 0.66 10.5 11.5 1.0 1 0 0 1 1 1 0 Apg6 coiled-coil region Med15 PF09606.10 RLN88480.1 - 1.4 7.5 13.6 1.5 7.4 13.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4524 PF15025.6 RLN88481.1 - 3e-12 46.5 0.0 4.8e-10 39.4 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4524) DUF4520 PF15016.6 RLN88481.1 - 1.3e-08 34.8 0.0 4.6e-08 33.0 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4520) Skp1 PF01466.19 RLN88482.1 - 0.0011 19.0 0.0 0.0011 19.0 0.0 2.2 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 RLN88482.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain DTHCT PF08070.11 RLN88482.1 - 1.9 9.3 20.7 0.5 11.1 15.9 2.4 1 1 1 2 2 2 0 DTHCT (NUC029) region NPR3 PF03666.13 RLN88482.1 - 2.7 6.7 8.9 4.2 6.1 8.9 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1754 PF08555.10 RLN88482.1 - 3 8.7 13.3 11 6.9 13.3 1.9 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) cwf21 PF08312.12 RLN88482.1 - 3.5 7.9 7.9 0.4 10.9 2.8 2.1 2 0 0 2 2 2 0 cwf21 domain Acatn PF13000.7 RLN88483.1 - 1.3e-120 403.5 11.4 1.6e-72 244.8 2.2 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DEAD PF00270.29 RLN88484.1 - 4.1e-46 156.9 0.5 8.2e-46 156.0 0.5 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN88484.1 - 1.3e-31 109.2 0.5 5.2e-31 107.3 0.1 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN88484.1 - 1.9e-05 24.7 0.0 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RLN88484.1 - 0.00032 21.1 1.2 0.0033 17.7 0.7 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RLN88484.1 - 0.00081 19.2 0.1 0.0013 18.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 RLN88484.1 - 0.0018 17.7 0.0 0.0044 16.4 0.0 1.6 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 RLN88484.1 - 0.0096 14.7 0.1 0.74 8.5 0.0 2.1 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 UvrD-helicase PF00580.21 RLN88484.1 - 0.041 13.4 0.2 0.069 12.7 0.2 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Flavi_DEAD PF07652.14 RLN88484.1 - 0.12 12.3 0.2 0.34 10.9 0.2 1.8 1 1 0 1 1 1 0 Flavivirus DEAD domain IBN_N PF03810.19 RLN88485.1 - 2.2e-06 27.5 1.7 4.1e-05 23.4 0.1 3.8 4 0 0 4 4 4 1 Importin-beta N-terminal domain UME PF08064.13 RLN88485.1 - 0.0025 17.7 0.9 0.1 12.5 0.1 3.7 4 0 0 4 4 4 1 UME (NUC010) domain Xpo1 PF08389.12 RLN88485.1 - 0.41 10.7 3.4 1.9 8.5 0.0 3.8 4 1 1 5 5 5 0 Exportin 1-like protein Glyco_transf_28 PF03033.20 RLN88486.1 - 2e-19 70.0 0.1 9.1e-19 67.9 0.1 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 RLN88486.1 - 1.8e-05 23.8 0.1 3.2e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 RLN88486.1 - 0.1 12.9 0.0 5.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain PARP_reg PF02877.14 RLN88486.1 - 0.18 11.9 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain EF-hand_6 PF13405.6 RLN88490.1 - 0.0013 18.5 7.6 0.47 10.5 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 RLN88490.1 - 0.015 15.7 2.5 0.3 11.6 0.0 3.0 4 0 0 4 4 4 0 EF-hand domain pair EF-hand_1 PF00036.32 RLN88490.1 - 0.18 11.4 2.7 0.4 10.3 0.0 2.8 3 0 0 3 3 3 0 EF hand Sigma_1s PF02454.16 RLN88492.1 - 2.8 8.0 9.0 0.27 11.2 1.1 2.3 2 0 0 2 2 2 0 Sigma 1s protein DCD PF06559.11 RLN88493.1 - 0.0014 17.5 0.0 0.0021 16.9 0.0 1.1 1 0 0 1 1 1 1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) UPF0176_N PF17773.1 RLN88494.1 - 1.1e-21 77.0 0.1 3.4e-21 75.4 0.0 2.0 2 0 0 2 2 2 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 RLN88494.1 - 1.7e-11 44.3 10.5 1.7e-11 44.3 10.5 1.9 2 0 0 2 2 2 1 Rhodanase C-terminal Rhodanese PF00581.20 RLN88494.1 - 1.8e-09 38.1 0.0 3.6e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain FYVE PF01363.21 RLN88494.1 - 8.2e-05 22.7 9.5 0.1 12.8 5.6 2.6 2 0 0 2 2 2 2 FYVE zinc finger zf-P11 PF03854.14 RLN88494.1 - 0.79 9.4 7.7 0.13 11.9 2.9 2.2 1 1 1 2 2 2 0 P-11 zinc finger IBR PF01485.21 RLN88494.1 - 2.2 8.6 9.3 16 5.8 4.3 2.9 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain Myotub-related PF06602.14 RLN88496.1 - 2.6e-113 378.6 0.1 4.6e-113 377.7 0.1 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Vps36_ESCRT-II PF11605.8 RLN88496.1 - 0.0064 16.7 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Y_phosphatase3 PF13350.6 RLN88496.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family PH_TFIIH PF08567.11 RLN88496.1 - 0.083 13.2 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain VPS13_C PF16909.5 RLN88496.1 - 0.25 11.1 3.5 0.44 10.3 3.5 1.3 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal IQ PF00612.27 RLN88497.1 - 0.003 17.2 1.9 0.0073 16.0 1.9 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Suf PF05843.14 RLN88498.1 - 1.3e-11 45.1 3.8 0.00014 22.0 0.0 5.6 4 1 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 RLN88498.1 - 1.5e-09 37.9 27.5 0.72 10.8 0.0 12.1 10 3 3 13 13 12 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN88498.1 - 2.1e-08 33.7 0.1 0.62 10.4 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 RLN88498.1 - 3.3e-07 30.3 9.7 0.038 14.0 0.0 6.9 7 3 1 8 8 8 2 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 RLN88498.1 - 1.4e-06 28.4 1.9 0.51 10.7 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat NRDE-2 PF08424.10 RLN88498.1 - 5.8e-06 25.7 8.3 1.3 8.0 0.0 5.7 1 1 1 5 5 5 2 NRDE-2, necessary for RNA interference TPR_2 PF07719.17 RLN88498.1 - 6.7e-06 25.8 5.2 2.6 8.4 0.0 7.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 RLN88498.1 - 2.5e-05 23.6 2.7 0.33 10.1 0.0 4.4 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN88498.1 - 0.0005 19.9 1.1 2.4 8.4 0.0 6.1 5 0 0 5 5 5 1 Tetratricopeptide repeat MerR_1 PF13411.6 RLN88498.1 - 0.021 14.9 0.1 6.2 7.0 0.0 2.8 2 0 0 2 2 2 0 MerR HTH family regulatory protein TPR_16 PF13432.6 RLN88498.1 - 0.027 15.1 3.5 16 6.2 0.0 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat SNAP PF14938.6 RLN88498.1 - 0.068 12.6 0.1 20 4.5 0.0 3.5 4 0 0 4 4 4 0 Soluble NSF attachment protein, SNAP Pox_Ag35 PF03286.14 RLN88498.1 - 0.65 9.8 7.7 0.25 11.1 2.0 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein TPR_1 PF00515.28 RLN88498.1 - 0.92 9.4 4.3 41 4.2 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat FAM176 PF14851.6 RLN88498.1 - 7.2 6.3 12.3 24 4.6 6.6 2.4 2 0 0 2 2 2 0 FAM176 family Cyclin_C PF02984.19 RLN88499.1 - 0.0093 16.0 0.4 0.02 15.0 0.4 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF1772 PF08592.11 RLN88499.1 - 0.034 14.5 1.4 0.061 13.6 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) BAR PF03114.18 RLN88500.1 - 0.025 14.2 0.9 0.032 13.9 0.9 1.2 1 0 0 1 1 1 0 BAR domain Vps5 PF09325.10 RLN88500.1 - 0.062 12.8 0.2 0.09 12.3 0.2 1.2 1 0 0 1 1 1 0 Vps5 C terminal like FAM92 PF06730.11 RLN88500.1 - 0.065 12.6 0.1 0.093 12.1 0.1 1.2 1 0 0 1 1 1 0 FAM92 protein Acyl-CoA_dh_1 PF00441.24 RLN88501.1 - 3.2e-14 53.4 0.2 5.9e-14 52.5 0.1 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RLN88501.1 - 1.9e-11 44.6 0.0 3.6e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 RLN88501.1 - 2.1e-09 37.5 0.0 3.6e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Adaptin_N PF01602.20 RLN88502.1 - 2.9e-17 62.4 0.0 3.4e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region hnRNP_Q_AcD PF18360.1 RLN88503.1 - 6.4e-23 80.5 0.2 5.1e-09 36.0 0.0 3.9 4 0 0 4 4 4 3 Heterogeneous nuclear ribonucleoprotein Q acidic domain UCH PF00443.29 RLN88504.1 - 1e-34 120.2 0.0 1.4e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN88504.1 - 0.0017 18.0 0.0 1.1 8.8 0.0 2.9 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase GrpE PF01025.19 RLN88505.1 - 1.3e-44 151.8 6.1 1.6e-44 151.5 6.1 1.1 1 0 0 1 1 1 1 GrpE TssR PF17643.1 RLN88505.1 - 0.032 12.2 0.4 0.041 11.8 0.4 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssR EF-hand_7 PF13499.6 RLN88505.1 - 0.047 14.2 0.2 0.15 12.5 0.0 1.9 2 1 0 2 2 2 0 EF-hand domain pair DUF5090 PF17009.5 RLN88506.1 - 0.079 12.9 0.9 0.12 12.3 0.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5090) Adaptin_N PF01602.20 RLN88507.1 - 1.1e-82 278.3 4.5 2.8e-56 191.2 2.2 2.0 1 1 1 2 2 2 2 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 RLN88507.1 - 1.6e-17 63.8 0.0 4.5e-17 62.4 0.0 1.8 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 RLN88507.1 - 5.6e-07 29.7 3.8 0.0059 16.7 0.6 3.0 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 RLN88507.1 - 0.00057 19.7 0.2 0.0047 16.7 0.0 2.6 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis HEAT PF02985.22 RLN88507.1 - 0.0054 16.9 0.3 0.27 11.6 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat Vac14_Fab1_bd PF12755.7 RLN88507.1 - 0.034 14.7 0.6 0.45 11.1 0.1 2.9 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 RLN88507.1 - 0.23 11.9 4.6 0.66 10.4 0.1 3.5 4 1 0 4 4 4 0 HEAT repeats MMS19_N PF14500.6 RLN88507.1 - 0.23 11.0 2.3 0.72 9.4 0.0 2.7 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Nipped-B_C PF12830.7 RLN88507.1 - 0.31 10.9 4.9 0.44 10.5 0.1 3.4 5 0 0 5 5 5 0 Sister chromatid cohesion C-terminus DUF3361 PF11841.8 RLN88507.1 - 0.72 9.8 3.3 0.53 10.2 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) TIP120 PF08623.10 RLN88507.1 - 5.5 6.7 5.3 6.7 6.5 0.2 3.1 3 1 1 4 4 4 0 TATA-binding protein interacting (TIP20) PPTA PF01239.22 RLN88508.1 - 9.5e-40 133.2 16.2 2.2e-09 36.7 0.2 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat NatB_MDM20 PF09797.9 RLN88508.1 - 0.031 13.2 0.1 0.048 12.6 0.1 1.2 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit AAA_lid_5 PF17865.1 RLN88508.1 - 0.12 12.4 0.0 5.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Midasin AAA lid domain Na_Pi_cotrans PF02690.15 RLN88509.1 - 9.9e-08 32.2 1.5 9.9e-08 32.2 1.5 2.1 1 1 1 2 2 2 1 Na+/Pi-cotransporter DUF4381 PF14316.6 RLN88509.1 - 0.017 15.4 0.7 0.017 15.4 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) FxsA PF04186.13 RLN88509.1 - 0.029 14.5 1.5 0.029 14.5 1.5 2.9 1 1 2 3 3 3 0 FxsA cytoplasmic membrane protein Bax1-I PF01027.20 RLN88509.1 - 0.037 13.9 15.2 0.053 13.4 15.2 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 MLANA PF14991.6 RLN88509.1 - 0.075 13.3 0.6 0.12 12.7 0.2 1.6 1 1 0 1 1 1 0 Protein melan-A Tetraspanin PF00335.20 RLN88509.1 - 0.18 11.5 2.7 0.22 11.2 2.7 1.2 1 0 0 1 1 1 0 Tetraspanin family FA_desaturase PF00487.24 RLN88509.1 - 0.38 10.5 7.2 0.49 10.2 7.2 1.2 1 0 0 1 1 1 0 Fatty acid desaturase DUF3810 PF12725.7 RLN88509.1 - 0.94 8.8 2.8 0.63 9.3 1.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) RCC1 PF00415.18 RLN88510.1 - 4.3e-16 59.3 0.2 1.2e-07 32.2 0.1 2.5 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat HHH_8 PF14716.6 RLN88510.1 - 1.1e-06 28.9 1.2 0.0014 18.9 0.3 3.1 3 0 0 3 3 3 2 Helix-hairpin-helix domain Spt5_N PF11942.8 RLN88510.1 - 0.0056 17.6 9.0 0.42 11.6 0.3 2.6 2 0 0 2 2 2 2 Spt5 transcription elongation factor, acidic N-terminal RCC1_2 PF13540.6 RLN88510.1 - 0.033 14.0 5.0 0.12 12.2 5.0 1.9 1 1 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat BSP_II PF05432.11 RLN88510.1 - 0.85 9.3 12.1 0.85 9.3 5.1 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) EGF_2 PF07974.13 RLN88511.1 - 0.0022 18.3 18.5 0.0087 16.4 8.4 2.4 2 0 0 2 2 2 2 EGF-like domain Laminin_EGF PF00053.24 RLN88511.1 - 0.79 9.9 12.9 4.3 7.6 6.3 2.3 2 0 0 2 2 2 0 Laminin EGF domain EGF PF00008.27 RLN88511.1 - 3.7 8.0 9.4 2 8.8 5.3 2.3 2 0 0 2 2 2 0 EGF-like domain Glyco_transf_41 PF13844.6 RLN88512.1 - 7.1e-74 248.9 0.2 7.3e-40 136.8 0.0 2.4 1 1 1 2 2 2 2 Glycosyl transferase family 41 Methyltransf_11 PF08241.12 RLN88512.1 - 1.5e-09 38.4 0.0 4.1e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain TPR_1 PF00515.28 RLN88512.1 - 4.3e-08 32.7 0.0 0.00014 21.5 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN88512.1 - 1.1e-07 32.3 0.1 2.9e-07 30.9 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN88512.1 - 1.4e-07 32.0 0.1 5.2e-07 30.2 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 RLN88512.1 - 1.2e-05 25.0 0.0 0.012 15.7 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN88512.1 - 1.7e-05 24.4 0.0 3.5e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 TPR repeat TPR_8 PF13181.6 RLN88512.1 - 4.3e-05 23.4 0.0 0.0004 20.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Methyltransf_25 PF13649.6 RLN88512.1 - 0.00012 22.7 0.0 0.00036 21.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain TPR_14 PF13428.6 RLN88512.1 - 0.00023 21.7 0.0 0.0012 19.5 0.0 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Methyltransf_12 PF08242.12 RLN88512.1 - 0.00064 20.4 0.0 0.0018 19.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain TPR_17 PF13431.6 RLN88512.1 - 0.0066 16.7 0.1 0.036 14.5 0.0 2.4 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN88512.1 - 0.0075 16.5 0.5 0.053 13.8 0.1 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN88512.1 - 0.008 16.8 0.0 0.45 11.3 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Methyltransf_23 PF13489.6 RLN88512.1 - 0.022 14.6 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TPR_7 PF13176.6 RLN88512.1 - 0.051 13.6 0.0 0.18 11.9 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN88512.1 - 0.085 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 RLN88512.1 - 1.7 9.5 5.1 0.72 10.7 0.1 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat VPS9 PF02204.18 RLN88513.1 - 9.4e-21 74.0 0.0 1.7e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 RLN88513.1 - 2.3e-07 31.0 0.0 6.5e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) FlhC PF05280.11 RLN88513.1 - 0.17 11.6 0.1 0.75 9.5 0.0 1.9 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhC) LCM PF04072.14 RLN88514.1 - 1.4e-36 126.3 0.0 1.7e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase LCM PF04072.14 RLN88515.1 - 1e-35 123.4 0.0 1.7e-35 122.7 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Merozoite_SPAM PF07133.11 RLN88516.1 - 0.43 10.5 16.4 0.57 10.2 16.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) TRAP_alpha PF03896.16 RLN88516.1 - 0.45 9.7 5.0 0.61 9.2 5.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RCSD PF05177.12 RLN88516.1 - 1 10.3 11.0 2.3 9.2 11.0 1.6 1 1 0 1 1 1 0 RCSD region AAA PF00004.29 RLN88518.1 - 7.6e-33 113.7 0.7 4.6e-27 95.0 0.1 3.5 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 RLN88518.1 - 1.7e-17 63.1 0.1 4e-17 61.9 0.1 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 RLN88518.1 - 3.7e-11 43.4 4.1 0.012 15.9 0.0 4.3 3 2 2 5 5 3 3 AAA domain AAA_16 PF13191.6 RLN88518.1 - 8.4e-11 42.5 0.2 0.00016 22.1 0.0 3.6 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 RLN88518.1 - 1.9e-10 40.9 1.9 0.0016 18.4 0.1 4.1 2 2 1 3 3 3 2 AAA domain (dynein-related subfamily) Torsin PF06309.11 RLN88518.1 - 2.9e-10 40.3 0.0 7.7e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 Torsin AAA_2 PF07724.14 RLN88518.1 - 1.8e-09 37.9 1.9 0.00018 21.7 0.7 3.8 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 RLN88518.1 - 1.8e-08 34.5 0.0 0.0032 17.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 RLN88518.1 - 6.8e-08 32.9 0.0 0.001 19.5 0.0 3.2 3 0 0 3 3 3 2 RNA helicase RuvB_N PF05496.12 RLN88518.1 - 1.2e-07 31.6 0.2 0.022 14.5 0.1 2.9 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 RLN88518.1 - 2.9e-06 27.4 0.1 0.0031 17.5 0.0 3.3 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_18 PF13238.6 RLN88518.1 - 5.7e-06 26.9 2.9 0.055 14.0 0.0 3.4 3 1 0 3 3 2 2 AAA domain PhoH PF02562.16 RLN88518.1 - 1.7e-05 24.4 0.1 0.39 10.1 0.0 3.3 3 0 0 3 3 3 2 PhoH-like protein AAA_33 PF13671.6 RLN88518.1 - 1.8e-05 24.9 0.0 0.0017 18.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 RLN88518.1 - 2.1e-05 24.5 0.8 0.39 10.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 RLN88518.1 - 0.0001 22.1 0.0 0.14 11.8 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 RLN88518.1 - 0.00012 21.8 0.1 0.44 10.2 0.0 3.2 2 1 1 3 3 3 2 Sigma-54 interaction domain AAA_30 PF13604.6 RLN88518.1 - 0.00018 21.3 3.7 1 9.1 0.1 4.0 2 2 0 2 2 2 2 AAA domain AAA_3 PF07726.11 RLN88518.1 - 0.00024 21.0 0.0 0.64 9.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 RLN88518.1 - 0.00026 20.8 0.0 0.3 10.8 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 RLN88518.1 - 0.00047 20.5 5.6 2.7 8.3 0.2 4.1 2 2 0 4 4 4 1 AAA domain TsaE PF02367.17 RLN88518.1 - 0.00063 19.8 0.0 0.43 10.6 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 RLN88518.1 - 0.00084 19.6 0.1 1.6 9.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 RLN88518.1 - 0.001 18.6 0.0 0.79 9.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region ABC_tran PF00005.27 RLN88518.1 - 0.0011 19.5 1.2 5.1 7.6 0.0 3.6 3 0 0 3 3 3 0 ABC transporter Zeta_toxin PF06414.12 RLN88518.1 - 0.0011 18.2 2.6 0.31 10.3 0.0 3.0 4 0 0 4 4 2 2 Zeta toxin KAP_NTPase PF07693.14 RLN88518.1 - 0.0012 18.2 0.1 0.16 11.2 0.0 2.4 1 1 0 2 2 2 1 KAP family P-loop domain T2SSE PF00437.20 RLN88518.1 - 0.0012 17.9 0.0 0.099 11.7 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein TIP49 PF06068.13 RLN88518.1 - 0.002 17.4 0.0 0.064 12.5 0.0 2.7 2 0 0 2 2 2 1 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 RLN88518.1 - 0.002 18.2 0.0 0.87 9.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 RLN88518.1 - 0.0021 17.5 0.0 0.12 11.8 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 RLN88518.1 - 0.0039 16.9 2.2 1.5 8.5 0.0 3.8 5 0 0 5 5 4 1 AAA domain NB-ARC PF00931.22 RLN88518.1 - 0.0074 15.5 0.0 3.1 6.9 0.0 2.8 2 0 0 2 2 2 1 NB-ARC domain AFG1_ATPase PF03969.16 RLN88518.1 - 0.012 14.5 0.0 4.2 6.1 0.0 2.5 2 0 0 2 2 2 0 AFG1-like ATPase CPT PF07931.12 RLN88518.1 - 0.013 15.3 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 RLN88518.1 - 0.022 14.5 0.1 9.1 5.9 0.0 2.9 3 0 0 3 3 2 0 Cytidylate kinase FlxA PF14282.6 RLN88518.1 - 0.028 14.4 0.8 0.15 12.0 0.4 2.3 2 0 0 2 2 2 0 FlxA-like protein IPT PF01745.16 RLN88518.1 - 0.031 13.6 0.2 2.1 7.7 0.0 2.6 3 0 0 3 3 2 0 Isopentenyl transferase AAA_lid_3 PF17862.1 RLN88518.1 - 0.044 13.6 1.3 0.49 10.2 0.1 2.7 2 0 0 2 2 2 0 AAA+ lid domain NACHT PF05729.12 RLN88518.1 - 0.045 13.7 0.1 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 NACHT domain DUF2075 PF09848.9 RLN88518.1 - 0.055 12.7 1.9 2.7 7.2 0.0 3.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 RLN88518.1 - 0.083 12.2 6.7 0.31 10.4 0.0 3.4 3 1 0 3 3 3 0 KaiC AAA_6 PF12774.7 RLN88518.1 - 0.083 11.8 0.2 0.92 8.4 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AAA_29 PF13555.6 RLN88518.1 - 0.18 11.5 0.1 33 4.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 RLN88518.1 - 0.21 11.5 3.5 2.9 7.8 0.1 3.4 4 0 0 4 4 3 0 NTPase AAA_25 PF13481.6 RLN88518.1 - 0.22 11.1 4.9 3.7 7.1 0.0 3.6 3 1 1 4 4 3 0 AAA domain AAA_23 PF13476.6 RLN88518.1 - 0.47 10.9 9.9 21 5.5 7.1 3.3 2 1 0 2 2 2 0 AAA domain Ion_trans PF00520.31 RLN88519.1 - 1.2e-17 64.0 7.8 1.6e-17 63.5 7.8 1.1 1 0 0 1 1 1 1 Ion transport protein MM_CoA_mutase PF01642.22 RLN88520.1 - 2.7e-193 643.2 0.0 3.1e-193 643.0 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase PhnI PF05861.12 RLN88520.1 - 0.08 11.8 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) Met_synt_B12 PF02965.17 RLN88521.1 - 2.4e-111 371.6 0.0 4.5e-111 370.7 0.0 1.5 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 RLN88521.1 - 6.4e-74 249.1 0.0 1.5e-73 247.9 0.0 1.7 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 RLN88521.1 - 1.1e-54 185.7 1.0 2.8e-54 184.4 1.0 1.7 1 0 0 1 1 1 1 Pterin binding enzyme B12-binding_2 PF02607.17 RLN88521.1 - 1.2e-23 83.4 0.1 1.2e-23 83.4 0.1 3.1 4 0 0 4 4 4 1 B12 binding domain B12-binding PF02310.19 RLN88521.1 - 1.4e-18 67.0 0.4 5e-18 65.3 0.4 2.0 1 0 0 1 1 1 1 B12 binding domain DUF2760 PF10816.8 RLN88521.1 - 0.07 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) Na_H_Exchanger PF00999.21 RLN88522.1 - 7.5e-13 48.0 36.6 2.5e-11 43.0 24.8 2.2 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family Pyr_redox_3 PF13738.6 RLN88522.1 - 0.0088 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase CRCB PF02537.15 RLN88523.1 - 6.4e-34 116.1 21.0 1.2e-17 64.0 3.6 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) DUF2628 PF10947.8 RLN88523.1 - 0.12 12.8 1.9 0.23 11.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) ECF_trnsprt PF12822.7 RLN88523.1 - 0.2 11.7 3.4 0.36 10.9 2.5 2.1 1 1 0 1 1 1 0 ECF transporter, substrate-specific component Phage_holin_5_2 PF16079.5 RLN88523.1 - 2.3 8.6 10.3 1.8 9.0 0.9 3.5 3 1 1 4 4 4 0 Phage holin family Hol44, in holin superfamily V PAE PF03283.13 RLN88524.1 - 4.5e-13 49.1 0.8 8.2e-13 48.2 0.8 1.4 1 1 0 1 1 1 1 Pectinacetylesterase DUF2235 PF09994.9 RLN88524.1 - 0.011 15.1 0.0 0.065 12.6 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_3 PF07859.13 RLN88524.1 - 0.07 13.0 0.0 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Myb_DNA-bind_4 PF13837.6 RLN88525.1 - 2.3e-13 50.3 1.2 0.0045 17.3 0.0 4.0 4 0 0 4 4 4 3 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 RLN88525.1 - 1.3e-08 35.7 2.8 0.061 14.3 0.0 3.7 4 0 0 4 4 4 3 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 RLN88525.1 - 1.2e-05 25.6 7.4 0.048 14.0 0.2 4.2 4 1 0 4 4 4 3 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 RLN88525.1 - 8.8e-05 22.5 3.2 0.11 12.6 0.2 3.8 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain DUF573 PF04504.14 RLN88525.1 - 0.0014 19.3 3.7 5.6 7.7 0.2 4.2 4 1 0 4 4 4 1 Protein of unknown function, DUF573 RPAP1_C PF08620.10 RLN88525.1 - 1.1 9.4 5.6 13 6.0 0.1 3.0 3 0 0 3 3 3 0 RPAP1-like, C-terminal TetR_C_15 PF17918.1 RLN88525.1 - 1.3 9.8 10.8 0.46 11.2 3.7 3.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain IFT20 PF14931.6 RLN88525.1 - 1.5 9.0 9.8 1.2 9.3 2.8 2.8 3 0 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 Bromodomain PF00439.25 RLN88526.1 - 1.4e-21 76.4 0.1 2.6e-21 75.5 0.1 1.5 1 0 0 1 1 1 1 Bromodomain COBRA1 PF06209.13 RLN88526.1 - 2.5e-11 43.2 2.8 0.0035 16.3 0.0 3.6 3 1 0 3 3 3 3 Cofactor of BRCA1 (COBRA1) C2 PF00168.30 RLN88527.1 - 7.4e-09 35.8 0.0 4.7e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 C2 domain zf-B_box PF00643.24 RLN88528.1 - 0.00069 19.7 4.9 0.0016 18.5 4.9 1.6 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 RLN88528.1 - 0.0046 17.2 4.4 0.015 15.6 4.4 1.8 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain UPF0242 PF06785.11 RLN88528.1 - 0.78 9.8 4.7 1.8 8.6 4.7 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus dCache_2 PF08269.11 RLN88528.1 - 4 6.5 4.6 5.6 6.0 4.6 1.2 1 0 0 1 1 1 0 Cache domain Acetyltransf_1 PF00583.25 RLN88529.1 - 4.9e-17 62.2 0.2 7.2e-17 61.7 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RLN88529.1 - 5.4e-09 36.4 0.1 9e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RLN88529.1 - 1.4e-08 34.7 0.2 2.1e-08 34.2 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN88529.1 - 1.1e-05 25.2 0.1 2.6e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 RLN88529.1 - 0.0014 18.7 0.2 0.0033 17.5 0.2 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 RLN88529.1 - 0.0041 17.8 0.1 0.0061 17.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 RLN88529.1 - 0.0069 16.3 0.1 0.014 15.4 0.1 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase CCDC84 PF14968.6 RLN88530.1 - 2e-52 179.0 5.0 2.9e-52 178.4 5.0 1.3 1 0 0 1 1 1 1 Coiled coil protein 84 ELM2 PF01448.24 RLN88530.1 - 0.022 15.5 0.1 0.058 14.2 0.1 1.7 1 0 0 1 1 1 0 ELM2 domain DEAD PF00270.29 RLN88531.1 - 1.6e-09 37.8 0.4 0.00033 20.5 0.0 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase CBS PF00571.28 RLN88531.1 - 0.049 14.1 0.0 0.13 12.7 0.0 1.7 2 0 0 2 2 2 0 CBS domain Helicase_C PF00271.31 RLN88531.1 - 0.16 12.4 0.0 0.51 10.7 0.0 1.9 1 1 0 1 1 1 0 Helicase conserved C-terminal domain Dimer_Tnp_hAT PF05699.14 RLN88532.1 - 2.5e-08 33.6 0.0 7.9e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 RLN88532.1 - 0.00073 19.5 0.4 0.0016 18.4 0.4 1.7 1 0 0 1 1 1 1 BED zinc finger RabGAP-TBC PF00566.18 RLN88533.1 - 6.7e-47 159.9 0.0 1e-46 159.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PDZ PF00595.24 RLN88533.1 - 4.5e-07 30.1 0.0 8.8e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RLN88533.1 - 3.3e-06 26.8 0.1 7.7e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Helitron_like_N PF14214.6 RLN88534.1 - 1.8e-09 38.1 0.2 4.5e-09 36.8 0.1 1.8 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus FAD_binding_7 PF03441.14 RLN88534.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase Ribosomal_L14e PF01929.17 RLN88535.1 - 7.4e-29 100.1 6.1 7.4e-29 100.1 6.1 1.4 1 1 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 RLN88535.1 - 0.0014 18.5 0.0 0.0032 17.4 0.0 1.6 1 0 0 1 1 1 1 KOW motif Ank_4 PF13637.6 RLN88536.1 - 8e-09 35.9 0.2 2.8e-05 24.6 0.1 3.1 2 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN88536.1 - 1.5e-07 31.5 1.7 0.013 15.8 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN88536.1 - 4.8e-05 23.9 0.0 0.00019 21.9 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN88536.1 - 0.0064 16.9 0.1 22 6.0 0.1 3.7 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 RLN88536.1 - 0.012 16.1 0.2 5.6 7.6 0.1 3.3 2 1 0 2 2 2 0 Ankyrin repeat DUF2040 PF09745.9 RLN88537.1 - 1.3e-33 115.6 13.6 1.3e-33 115.6 13.6 2.2 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) Ribosomal_L5e PF17144.4 RLN88538.1 - 3e-82 274.5 1.6 3e-82 274.5 1.6 2.3 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 RLN88538.1 - 3e-26 92.2 7.6 3e-26 92.2 7.6 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region NusG_add PF18298.1 RLN88538.1 - 0.004 17.4 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 NusG additional domain 2-oxoacid_dh PF00198.23 RLN88539.1 - 1.4e-77 260.2 0.1 2e-77 259.8 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 RLN88539.1 - 1.4e-36 124.2 10.0 1.3e-19 69.8 3.3 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme GCV_H PF01597.19 RLN88539.1 - 0.0015 18.4 4.3 0.22 11.4 0.7 2.5 2 0 0 2 2 2 2 Glycine cleavage H-protein HlyD_3 PF13437.6 RLN88539.1 - 0.0027 18.4 12.7 0.065 13.9 0.4 3.9 2 2 2 4 4 4 3 HlyD family secretion protein PYNP_C PF07831.13 RLN88539.1 - 0.59 9.8 2.8 18 5.0 0.1 3.0 3 0 0 3 3 3 0 Pyrimidine nucleoside phosphorylase C-terminal domain Ribosomal_60s PF00428.19 RLN88539.1 - 6.3 7.5 15.2 0.6 10.7 1.9 3.6 2 1 1 3 3 3 0 60s Acidic ribosomal protein Homeobox_KN PF05920.11 RLN88540.1 - 4.9e-16 58.4 0.0 1.1e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 RLN88540.1 - 3.7e-08 33.1 0.1 8e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 Homeodomain PQ-loop PF04193.14 RLN88541.1 - 1.6e-21 75.8 8.6 1.7e-10 40.5 1.9 2.3 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 RLN88541.1 - 6.2e-05 23.8 1.4 0.017 16.0 0.4 2.7 1 1 1 2 2 2 2 ER lumen protein retaining receptor MtN3_slv PF03083.16 RLN88541.1 - 0.00059 19.8 8.5 0.011 15.8 1.1 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange DUF4010 PF13194.6 RLN88541.1 - 0.016 14.9 1.9 0.059 13.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) DUF2070 PF09843.9 RLN88541.1 - 0.019 13.3 0.3 0.35 9.1 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) SYS1 PF09801.9 RLN88541.1 - 0.029 14.5 4.7 0.19 11.9 0.5 2.2 2 0 0 2 2 2 0 Integral membrane protein S linking to the trans Golgi network DUF4191 PF13829.6 RLN88541.1 - 0.12 11.7 1.1 8.5 5.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF4233 PF14017.6 RLN88541.1 - 0.58 10.5 5.6 1.7 9.0 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4233) DUF4131 PF13567.6 RLN88541.1 - 4.2 7.0 6.2 1.7 8.3 0.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Dynein_light PF01221.18 RLN88542.1 - 7.5e-23 80.7 0.1 8.8e-23 80.4 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 DUF4854 PF16146.5 RLN88542.1 - 0.0039 17.5 0.1 0.0047 17.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4854) Ground-like PF04155.18 RLN88542.1 - 0.023 15.3 0.0 0.033 14.8 0.0 1.2 1 0 0 1 1 1 0 Ground-like domain Peptidase_S49_N PF08496.10 RLN88542.1 - 0.032 14.3 0.3 0.036 14.1 0.3 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SH3_14 PF18343.1 RLN88542.1 - 0.036 14.2 0.1 0.042 13.9 0.1 1.1 1 0 0 1 1 1 0 Dda helicase SH3 domain COOH-NH2_lig PF14395.6 RLN88542.1 - 0.11 11.7 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Phage phiEco32-like COOH.NH2 ligase-type 2 DUF3522 PF12036.8 RLN88544.1 - 2.6e-25 89.8 1.3 3.2e-25 89.5 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) THF_DHG_CYH_C PF02882.19 RLN88545.1 - 1e-64 216.7 0.3 2.3e-64 215.5 0.3 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 RLN88545.1 - 2e-31 108.7 0.0 2.9e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AlaDh_PNT_C PF01262.21 RLN88545.1 - 0.065 12.5 1.2 0.41 9.9 0.3 2.3 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Haem_degrading PF03928.14 RLN88545.1 - 0.092 12.8 1.0 0.5 10.4 0.2 2.2 2 0 0 2 2 2 0 Haem-degrading Ank_2 PF12796.7 RLN88546.1 - 2.9e-26 91.9 6.9 6.8e-08 33.0 2.7 4.8 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN88546.1 - 3.9e-21 75.1 8.8 2.1e-05 25.0 0.1 6.9 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN88546.1 - 3.1e-20 72.0 12.8 1.6e-06 28.3 0.8 6.0 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN88546.1 - 1.8e-17 61.6 10.8 0.065 13.8 0.0 8.7 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 RLN88546.1 - 3e-13 49.6 25.7 0.002 18.5 0.2 8.9 10 0 0 10 10 10 4 Ankyrin repeat zf-TAZ PF02135.16 RLN88547.1 - 7.5e-08 32.7 17.7 1.2e-07 32.1 17.7 1.3 1 0 0 1 1 1 1 TAZ zinc finger DUF3987 PF13148.6 RLN88547.1 - 0.038 13.0 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DNA_ligase_A_M PF01068.21 RLN88548.1 - 3.6e-55 186.8 0.2 3.6e-55 186.8 0.2 2.5 2 1 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 RLN88548.1 - 4.8e-40 137.7 0.1 4.8e-40 137.7 0.1 2.4 3 0 0 3 3 3 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 RLN88548.1 - 6.8e-24 84.3 2.0 1.5e-23 83.2 0.0 2.7 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region KNOX1 PF03790.13 RLN88548.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 KNOX1 domain MHC_II_beta PF00969.19 RLN88548.1 - 0.16 12.1 0.0 0.44 10.7 0.0 1.7 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain RNase_H2-Ydr279 PF09468.10 RLN88549.1 - 1.1e-11 45.1 0.0 2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 RLN88549.1 - 4.3e-05 23.7 0.0 0.00013 22.2 0.0 1.8 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain Bromodomain PF00439.25 RLN88550.1 - 4.1e-17 62.0 0.0 7e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 RLN88550.1 - 1e-09 38.1 11.7 1e-09 38.1 11.7 2.3 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 RLN88550.1 - 0.017 14.6 4.9 0.047 13.3 4.9 1.8 1 0 0 1 1 1 0 PHD-finger zf-CCHC_2 PF13696.6 RLN88550.1 - 7.8 6.4 7.2 0.33 10.8 0.5 2.1 2 0 0 2 2 2 0 Zinc knuckle HSF_DNA-bind PF00447.17 RLN88552.1 - 2e-25 89.2 0.7 4.1e-25 88.2 0.7 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding RapA_C PF12137.8 RLN88552.1 - 0.0013 17.9 4.7 0.0019 17.3 4.7 1.2 1 0 0 1 1 1 1 RNA polymerase recycling family C-terminal APG6_N PF17675.1 RLN88552.1 - 0.17 12.4 4.9 0.25 11.9 4.9 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region YabA PF06156.13 RLN88552.1 - 0.61 10.8 3.9 0.66 10.6 2.8 1.5 1 1 0 1 1 1 0 Initiation control protein YabA PspB PF06667.12 RLN88552.1 - 1.5 8.9 5.1 3.7 7.7 2.8 2.5 2 1 0 2 2 2 0 Phage shock protein B DUF3123 PF11321.8 RLN88552.1 - 3.1 8.5 8.7 1.4 9.6 6.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Ecm33 PF12454.8 RLN88553.1 - 0.059 13.5 0.2 0.11 12.7 0.2 1.4 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Spc7 PF08317.11 RLN88554.1 - 0.0013 17.7 3.7 0.0015 17.5 3.7 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF2780 PF11075.8 RLN88554.1 - 0.0068 16.6 2.3 0.0075 16.4 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function VcgC/VcgE (DUF2780) ADIP PF11559.8 RLN88554.1 - 0.0097 16.0 4.9 0.013 15.6 4.9 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF720 PF05302.11 RLN88554.1 - 0.019 14.8 0.7 0.022 14.6 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF720) DUF3584 PF12128.8 RLN88554.1 - 0.04 11.5 5.4 0.044 11.3 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NYD-SP28 PF14772.6 RLN88554.1 - 0.074 13.1 5.5 0.1 12.6 5.5 1.2 1 0 0 1 1 1 0 Sperm tail Golgin_A5 PF09787.9 RLN88554.1 - 0.088 12.3 4.9 0.1 12.1 4.9 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 PKcGMP_CC PF16808.5 RLN88554.1 - 0.1 12.5 1.1 0.1 12.5 1.1 2.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF641 PF04859.12 RLN88554.1 - 0.18 12.2 4.5 0.68 10.3 4.5 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) GvpL_GvpF PF06386.11 RLN88554.1 - 0.24 11.3 4.0 0.31 11.0 3.4 1.4 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Tup_N PF08581.10 RLN88554.1 - 0.37 11.1 5.0 14 6.0 0.4 2.9 1 1 2 3 3 3 0 Tup N-terminal DivIC PF04977.15 RLN88554.1 - 0.5 10.2 4.2 0.86 9.4 1.8 2.2 1 1 1 2 2 2 0 Septum formation initiator HR1 PF02185.16 RLN88554.1 - 3.8 7.7 12.0 1.1 9.4 4.6 2.2 1 1 1 2 2 2 0 Hr1 repeat eIF-5a PF01287.20 RLN88555.1 - 7.9e-05 22.7 0.1 0.00015 21.8 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold ArgJ PF01960.18 RLN88556.1 - 8.6e-102 340.7 0.0 3.3e-53 180.8 0.0 2.1 1 1 1 2 2 2 2 ArgJ family CAP_N PF01213.19 RLN88557.1 - 0.009 15.5 6.7 0.009 15.5 6.7 2.0 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 RLN88557.1 - 0.01 15.9 4.5 0.018 15.1 4.5 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 VIR_N PF15912.5 RLN88557.1 - 0.013 15.1 3.6 0.016 14.9 3.6 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal DUF3292 PF11696.8 RLN88557.1 - 0.15 10.4 4.8 0.2 10.0 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Ank_2 PF12796.7 RLN88559.1 - 1.7e-35 121.5 0.6 6.2e-09 36.3 0.0 6.3 1 1 6 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN88559.1 - 9.7e-31 102.4 13.9 0.0015 18.8 0.0 9.6 9 1 1 10 10 10 6 Ankyrin repeat Ank PF00023.30 RLN88559.1 - 1.7e-29 101.0 20.0 1.3e-06 28.6 0.0 8.5 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 RLN88559.1 - 1.9e-26 92.0 7.8 2.9e-10 40.5 0.1 8.2 5 2 4 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN88559.1 - 1e-22 79.9 18.1 5.8e-10 39.2 0.1 7.5 8 0 0 8 8 8 5 Ankyrin repeats (many copies) TIR_2 PF13676.6 RLN88559.1 - 2.8e-15 57.0 0.0 3.2e-08 34.2 0.0 2.6 2 0 0 2 2 2 2 TIR domain TIR PF01582.20 RLN88559.1 - 0.0012 18.7 0.2 1.4 8.7 0.1 2.3 2 0 0 2 2 2 2 TIR domain SGS PF05002.15 RLN88560.1 - 0.0037 17.3 0.0 0.0085 16.2 0.0 1.6 1 0 0 1 1 1 1 SGS domain CS PF04969.16 RLN88560.1 - 0.022 15.8 0.2 0.055 14.5 0.2 1.7 1 1 0 1 1 1 0 CS domain T3RM_EcoP15I_C PF18273.1 RLN88561.1 - 0.49 10.7 3.0 0.27 11.5 0.5 1.8 2 0 0 2 2 2 0 Type III R-M EcoP15I C-terminal domain Fumble PF03630.14 RLN88562.1 - 1.8e-97 326.5 1.5 1.1e-84 284.5 0.5 2.1 1 1 1 2 2 2 2 Fumble DUF587 PF04532.12 RLN88562.1 - 0.039 13.2 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF587) Aldo_ket_red PF00248.21 RLN88564.1 - 8.5e-14 51.4 0.1 9.2e-14 51.3 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LPMO_10 PF03067.15 RLN88565.1 - 1.1e-05 26.1 0.0 0.00039 21.2 0.0 2.3 1 1 1 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Med3 PF11593.8 RLN88565.1 - 2.1 7.5 13.0 3.1 6.9 13.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pyr_redox_2 PF07992.14 RLN88567.1 - 1.7e-23 83.3 0.7 2.1e-23 83.0 0.7 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RLN88567.1 - 1.7e-10 41.3 2.0 2e-06 28.3 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RLN88567.1 - 1.2e-08 34.5 0.2 4.8e-06 25.9 0.1 2.3 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 RLN88567.1 - 1.5e-08 34.7 1.7 0.00067 19.3 0.3 2.5 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 RLN88567.1 - 5.5e-08 32.4 1.1 0.00047 19.5 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RLN88567.1 - 2.9e-07 30.6 0.3 0.00031 20.9 0.1 2.4 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 RLN88567.1 - 8.5e-07 28.4 0.2 0.024 13.7 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 RLN88567.1 - 2.6e-06 27.5 0.3 0.0016 18.4 0.1 3.1 2 1 1 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 RLN88567.1 - 1.4e-05 24.0 1.6 0.002 16.9 0.1 2.4 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.17 RLN88567.1 - 1.6e-05 24.3 0.2 0.0056 16.0 0.0 2.2 2 0 0 2 2 2 2 Thi4 family Trp_halogenase PF04820.14 RLN88567.1 - 6.9e-05 21.9 1.6 0.0009 18.2 0.2 2.1 2 0 0 2 2 2 1 Tryptophan halogenase TrkA_N PF02254.18 RLN88567.1 - 9.7e-05 22.6 0.3 0.15 12.3 0.0 2.5 2 0 0 2 2 2 2 TrkA-N domain AlaDh_PNT_C PF01262.21 RLN88567.1 - 0.0003 20.1 0.3 0.42 9.9 0.1 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 RLN88567.1 - 0.0016 17.6 1.4 0.53 9.3 0.3 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 RLN88567.1 - 0.0029 16.9 2.0 0.009 15.3 0.1 2.3 3 0 0 3 3 3 1 FAD binding domain Methyltransf_34 PF11312.8 RLN88567.1 - 0.0043 16.4 0.2 0.34 10.1 0.1 2.2 2 0 0 2 2 2 1 Putative SAM-dependent methyltransferase Shikimate_DH PF01488.20 RLN88567.1 - 0.0053 16.8 0.6 1.8 8.6 0.1 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 RLN88567.1 - 0.0061 17.0 0.2 2.8 8.4 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 RLN88567.1 - 0.0064 16.8 0.3 0.38 11.0 0.0 2.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Malic_M PF03949.15 RLN88567.1 - 0.013 14.8 0.6 1.5 8.0 0.1 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain FAD_binding_2 PF00890.24 RLN88567.1 - 0.015 14.4 1.8 0.031 13.4 0.2 2.0 2 0 0 2 2 2 0 FAD binding domain PRMT5 PF05185.16 RLN88567.1 - 0.068 13.0 0.3 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase StbA PF06406.11 RLN88567.1 - 0.072 12.3 0.1 4.4 6.5 0.1 2.2 2 0 0 2 2 2 0 StbA protein Ldh_1_N PF00056.23 RLN88567.1 - 0.081 13.0 0.3 0.71 10.0 0.0 2.2 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Ank_2 PF12796.7 RLN88568.1 - 0.00099 19.6 0.0 0.002 18.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Iwr1 PF08574.10 RLN88568.1 - 0.0039 18.2 3.6 0.012 16.6 3.6 1.9 1 0 0 1 1 1 1 Transcription factor Iwr1 Ank PF00023.30 RLN88568.1 - 0.13 12.7 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat HSF_DNA-bind PF00447.17 RLN88569.1 - 9.1e-12 45.4 0.6 1.5e-11 44.7 0.6 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding SR-25 PF10500.9 RLN88569.1 - 0.064 12.9 5.2 0.08 12.5 5.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HSF_DNA-bind PF00447.17 RLN88570.1 - 1.9e-21 76.5 0.3 2.8e-21 75.9 0.3 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Aldo_ket_red PF00248.21 RLN88571.1 - 3.8e-37 128.1 0.0 4.3e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.7 RLN88573.1 - 8.6e-10 38.7 0.2 9.2e-05 22.7 0.1 3.4 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN88573.1 - 6.2e-07 29.1 0.1 0.041 13.4 0.0 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 RLN88573.1 - 0.031 14.1 4.8 0.21 11.3 0.3 3.6 2 2 1 3 3 3 0 Leucine rich repeat FYVE PF01363.21 RLN88574.1 - 0.00016 21.7 2.9 0.00016 21.7 2.9 1.6 2 0 0 2 2 2 1 FYVE zinc finger SDF PF00375.18 RLN88579.1 - 1.8e-13 50.3 10.8 2.5e-07 30.1 2.2 2.4 2 1 0 2 2 2 2 Sodium:dicarboxylate symporter family YfhO PF09586.10 RLN88579.1 - 0.16 10.1 0.2 0.24 9.6 0.2 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Ribosomal_S11 PF00411.19 RLN88580.1 - 2.2e-46 156.8 1.8 3.2e-46 156.3 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.9 RLN88580.1 - 0.031 13.4 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) GPS PF01825.21 RLN88581.1 - 4.7e-10 39.8 3.9 4.7e-10 39.8 3.9 2.9 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif AAA_13 PF13166.6 RLN88581.1 - 0.084 11.5 13.9 0.13 10.9 13.9 1.1 1 0 0 1 1 1 0 AAA domain FANCL_C PF11793.8 RLN88583.1 - 0.00031 20.9 5.3 0.00078 19.6 5.3 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.6 RLN88583.1 - 0.02 15.1 4.4 0.038 14.2 4.4 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Pap_E4 PF02711.14 RLN88583.1 - 0.11 13.4 3.3 0.28 12.2 3.3 1.6 1 0 0 1 1 1 0 E4 protein Nas2_N PF18265.1 RLN88584.1 - 2.7e-14 52.8 0.0 5.3e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 RLN88584.1 - 4.8e-10 39.1 0.2 9e-10 38.3 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RLN88584.1 - 1.7e-06 28.3 0.0 2.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RLN88584.1 - 2.6e-05 24.5 0.0 6.5e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 RLN88584.1 - 0.0014 18.9 0.0 0.0023 18.3 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain ABC_membrane_2 PF06472.15 RLN88585.1 - 1e-84 284.1 5.0 1.4e-84 283.7 5.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 RLN88585.1 - 5.9e-17 62.5 0.0 1.5e-16 61.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN88585.1 - 7.1e-06 25.6 0.1 0.11 11.9 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RLN88585.1 - 0.0026 17.6 0.0 0.0054 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Adeno_IVa2 PF02456.15 RLN88585.1 - 0.0038 16.1 0.0 0.0097 14.7 0.0 1.6 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_23 PF13476.6 RLN88585.1 - 0.05 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RLN88585.1 - 0.14 12.7 0.0 0.35 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Kazal_1 PF00050.21 RLN88587.1 - 1.2e-35 121.3 30.8 1.4e-10 41.0 3.3 4.6 4 0 0 4 4 4 4 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 RLN88587.1 - 1.5e-34 117.9 45.0 6.6e-10 39.0 0.3 5.0 5 0 0 5 5 5 4 Kazal-type serine protease inhibitor domain Aldo_ket_red PF00248.21 RLN88588.1 - 2.8e-56 190.9 0.0 3.5e-55 187.3 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family DUF2777 PF10949.8 RLN88588.1 - 0.19 11.4 0.0 0.41 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) DUF4799 PF16056.5 RLN88588.1 - 0.19 10.9 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4799) Aldo_ket_red PF00248.21 RLN88589.1 - 3.6e-66 223.3 0.0 4.1e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PAN_1 PF00024.26 RLN88591.1 - 1.1e-09 38.1 0.7 1.8e-09 37.4 0.7 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 RLN88591.1 - 5.8e-08 32.5 1.1 5.8e-08 32.5 1.1 2.1 2 1 0 2 2 2 1 PAN domain PAN_2 PF08276.11 RLN88591.1 - 0.008 16.3 1.5 0.008 16.3 1.5 2.1 2 0 0 2 2 2 1 PAN-like domain PAN_1 PF00024.26 RLN88592.1 - 4.6e-11 42.5 0.3 7.8e-11 41.8 0.3 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 RLN88592.1 - 1.8e-09 37.4 2.2 1.8e-09 37.4 2.2 2.2 2 0 0 2 2 2 1 PAN domain PAN_1 PF00024.26 RLN88593.1 - 1.8e-20 72.7 14.7 1.1e-11 44.5 5.4 3.1 2 1 0 2 2 2 2 PAN domain PAN_4 PF14295.6 RLN88593.1 - 6.8e-17 61.1 10.0 7.4e-10 38.6 1.7 3.2 3 1 0 3 3 3 2 PAN domain PAN_2 PF08276.11 RLN88593.1 - 0.0088 16.1 2.8 0.0088 16.1 2.8 3.9 4 0 0 4 4 4 2 PAN-like domain PAN_1 PF00024.26 RLN88594.1 - 6.5e-21 74.1 11.2 2.8e-11 43.2 1.5 2.8 2 1 0 2 2 2 2 PAN domain PAN_4 PF14295.6 RLN88594.1 - 2.6e-18 65.7 11.9 2.3e-10 40.2 3.0 3.8 4 0 0 4 4 4 2 PAN domain PAN_2 PF08276.11 RLN88594.1 - 0.014 15.5 0.9 0.014 15.5 0.9 3.0 3 0 0 3 3 3 0 PAN-like domain Granulin PF00396.18 RLN88594.1 - 0.044 14.1 7.1 0.044 14.1 7.1 4.1 4 0 0 4 4 4 0 Granulin FA_desaturase PF00487.24 RLN88597.1 - 6.2e-27 95.0 16.3 8.9e-27 94.5 16.3 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 RLN88597.1 - 3.3e-05 24.1 0.0 6.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Fumarate_red_C PF02300.17 RLN88597.1 - 1.3 9.1 7.3 1.9 8.6 2.4 2.7 2 1 0 2 2 2 0 Fumarate reductase subunit C FA_desaturase PF00487.24 RLN88598.1 - 6.1e-28 98.3 16.2 9e-28 97.8 16.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 RLN88598.1 - 2.1e-05 24.8 0.0 4.3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Fumarate_red_C PF02300.17 RLN88598.1 - 3.6 7.7 7.4 1.6 8.8 2.1 2.4 2 1 0 2 2 2 0 Fumarate reductase subunit C G-patch PF01585.23 RLN88599.1 - 1.1e-13 50.8 2.2 2.5e-13 49.7 0.9 2.2 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 RLN88599.1 - 2.7e-08 33.8 0.4 2.7e-08 33.8 0.4 2.6 2 1 0 2 2 2 1 G-patch domain SR-25 PF10500.9 RLN88599.1 - 0.0099 15.5 21.2 0.0099 15.5 21.2 2.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 RLN88599.1 - 0.018 13.3 8.7 0.02 13.2 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Coilin_N PF15862.5 RLN88599.1 - 0.051 13.4 11.6 0.075 12.8 11.6 1.3 1 0 0 1 1 1 0 Coilin N-terminus RR_TM4-6 PF06459.12 RLN88599.1 - 0.084 12.7 9.9 0.1 12.4 9.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 RLN88599.1 - 0.084 13.0 5.2 0.11 12.7 5.2 1.2 1 0 0 1 1 1 0 DDHD domain Glypican PF01153.19 RLN88599.1 - 0.093 11.6 4.5 0.11 11.3 4.5 1.1 1 0 0 1 1 1 0 Glypican DUF3807 PF12720.7 RLN88599.1 - 0.18 12.1 14.4 0.25 11.6 14.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Dsh_C PF12316.8 RLN88599.1 - 0.23 11.8 10.9 0.4 11.0 10.9 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal RNA_pol_Rpc4 PF05132.14 RLN88599.1 - 0.36 11.3 8.3 0.52 10.7 8.3 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Peptidase_S49_N PF08496.10 RLN88599.1 - 0.36 10.9 7.9 0.54 10.3 7.9 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CobT PF06213.12 RLN88599.1 - 0.67 9.3 8.3 0.9 8.9 8.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT WLM PF08325.10 RLN88599.1 - 0.72 9.9 6.5 1.2 9.1 6.5 1.3 1 0 0 1 1 1 0 WLM domain Vfa1 PF08432.10 RLN88599.1 - 0.98 9.7 16.0 1.4 9.2 16.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CCDC106 PF15794.5 RLN88599.1 - 1.1 8.9 14.5 1.6 8.4 14.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 RNA_polI_A34 PF08208.11 RLN88599.1 - 1.6 8.8 23.6 2.4 8.2 23.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 EOS1 PF12326.8 RLN88599.1 - 2.6 8.0 4.0 3.2 7.7 4.0 1.2 1 0 0 1 1 1 0 N-glycosylation protein Presenilin PF01080.17 RLN88599.1 - 2.9 6.5 7.1 3.6 6.3 7.1 1.1 1 0 0 1 1 1 0 Presenilin DUF4614 PF15391.6 RLN88599.1 - 3.6 7.6 11.6 6.3 6.8 11.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Med19 PF10278.9 RLN88599.1 - 3.9 7.4 20.2 6 6.8 20.2 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Zip PF02535.22 RLN88599.1 - 4.3 6.5 5.6 5.4 6.1 5.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 RLN88599.1 - 5.1 5.8 10.8 6.1 5.5 10.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3464 PF11947.8 RLN88599.1 - 7 6.4 9.4 11 5.7 9.4 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Connexin PF00029.19 RLN88599.1 - 9.7 5.9 7.0 13 5.5 7.0 1.2 1 0 0 1 1 1 0 Connexin RRM_1 PF00076.22 RLN88600.1 - 1.2e-59 198.0 9.3 1.9e-12 46.8 0.1 8.2 7 1 0 7 7 7 7 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RLN88600.1 - 6.7e-06 25.9 1.1 0.0025 17.6 0.1 4.7 6 0 0 6 6 6 1 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 RLN88600.1 - 0.0011 18.7 0.0 0.5 10.2 0.0 3.4 3 0 0 3 3 3 2 Rrp7 RRM-like N-terminal domain RRM_5 PF13893.6 RLN88600.1 - 0.0032 17.1 0.2 2.4 7.8 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN88600.1 - 0.047 13.8 0.1 8.6 6.6 0.0 3.7 4 0 0 4 4 4 0 RNA recognition motif FA_desaturase PF00487.24 RLN88601.1 - 2.9e-27 96.1 16.7 4.4e-27 95.5 16.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 RLN88601.1 - 1.1e-05 25.6 0.0 2.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) PDEase_I PF00233.19 RLN88602.1 - 4.2e-39 134.7 0.0 4.1e-37 128.2 0.0 2.4 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ribosomal_L36e PF01158.18 RLN88602.1 - 3.9e-20 71.9 2.2 1.8e-14 53.7 0.6 2.8 2 0 0 2 2 2 2 Ribosomal protein L36e Aha1_N PF09229.11 RLN88603.1 - 2.4e-19 69.9 0.0 6.4e-19 68.5 0.0 1.7 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal TPR_1 PF00515.28 RLN88603.1 - 9.6e-10 37.9 4.1 0.0002 21.1 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN88603.1 - 2.9e-07 30.1 9.3 0.0018 18.3 0.3 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN88603.1 - 0.00042 20.3 3.1 0.18 12.1 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN88603.1 - 0.00058 20.5 4.1 0.46 11.4 0.0 3.6 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN88603.1 - 0.00092 18.8 0.9 0.034 13.8 0.1 2.7 2 1 1 3 3 3 1 TPR repeat TPR_16 PF13432.6 RLN88603.1 - 0.0034 18.0 16.8 0.0078 16.8 4.0 3.1 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN88603.1 - 0.025 15.1 9.4 0.034 14.7 2.5 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4850 PF16142.5 RLN88603.1 - 0.048 13.1 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4850) Fis1_TPR_C PF14853.6 RLN88603.1 - 0.063 13.4 0.7 0.14 12.2 0.7 1.5 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat UFC1 PF08694.11 RLN88603.1 - 0.067 12.8 0.0 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 ANAPC3 PF12895.7 RLN88603.1 - 0.56 10.5 5.1 2.2 8.6 4.8 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 RLN88603.1 - 0.57 10.5 6.4 3.7 7.9 1.3 2.9 1 1 0 2 2 2 0 Tetratricopeptide repeat FANCI_S1 PF14675.6 RLN88606.1 - 1.3e-20 74.0 0.2 1.4e-14 54.2 0.1 2.1 2 0 0 2 2 2 2 FANCI solenoid 1 FANCI_HD1 PF14679.6 RLN88606.1 - 0.0002 21.2 0.1 0.00079 19.3 0.1 2.0 2 0 0 2 2 2 1 FANCI helical domain 1 FANCI_HD2 PF14680.6 RLN88607.1 - 6.8e-31 107.4 0.3 1.2e-30 106.5 0.3 1.4 1 0 0 1 1 1 1 FANCI helical domain 2 FANCI_S2 PF14676.6 RLN88607.1 - 2.3e-26 93.1 0.8 5.5e-26 91.8 0.8 1.7 1 0 0 1 1 1 1 FANCI solenoid 2 FANCI_S4 PF14678.6 RLN88607.1 - 1.4e-20 73.5 0.0 3e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 FANCI solenoid 4 DUF1810 PF08837.11 RLN88607.1 - 0.14 11.9 0.1 12 5.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1810) Sam68-YY PF16568.5 RLN88611.1 - 0.12 13.2 18.8 5.9 7.7 1.5 3.4 3 0 0 3 3 3 0 Tyrosine-rich domain of Sam68 Aldo_ket_red PF00248.21 RLN88613.1 - 1.1e-07 31.4 0.1 1.2e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family BT1 PF03092.16 RLN88614.1 - 1.2e-16 60.1 14.1 2.5e-12 45.8 0.7 3.2 3 0 0 3 3 3 3 BT1 family UPF0154 PF03672.13 RLN88615.1 - 0.0019 18.2 1.4 4.7 7.3 0.1 3.3 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) DUF188 PF02639.14 RLN88615.1 - 0.047 13.4 0.3 0.13 11.9 0.1 1.9 2 1 0 2 2 2 0 Uncharacterized BCR, YaiI/YqxD family COG1671 Tom5 PF10642.9 RLN88615.1 - 1.1 9.3 10.0 7.8 6.6 1.3 4.4 4 0 0 4 4 4 0 Mitochondrial import receptor subunit or translocase RSB_motif PF16294.5 RLN88615.1 - 2.1 8.7 10.9 0.86 9.9 0.2 3.8 4 0 0 4 4 4 0 RNSP1-SAP18 binding (RSB) motif Pkinase_Tyr PF07714.17 RLN88616.1 - 2.1e-43 148.5 0.0 4.6e-43 147.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RLN88616.1 - 2.1e-41 142.0 0.0 5.7e-41 140.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Ank_2 PF12796.7 RLN88616.1 - 1.2e-07 32.2 0.0 3.4e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN88616.1 - 1.7e-05 25.0 0.2 5e-05 23.5 0.2 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN88616.1 - 0.00021 21.8 0.1 0.00086 19.8 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN88616.1 - 0.0009 19.5 0.0 0.0073 16.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 RLN88616.1 - 0.0016 18.8 0.1 0.1 13.1 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat FCD PF07729.12 RLN88616.1 - 0.083 13.3 0.1 0.38 11.2 0.0 2.2 2 0 0 2 2 2 0 FCD domain TTRAP PF14203.6 RLN88616.1 - 0.096 12.7 0.9 0.61 10.1 0.2 2.4 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein Ribonuclease_T2 PF00445.18 RLN88617.1 - 5.8e-25 88.6 0.2 7.8e-25 88.2 0.2 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Pkinase_Tyr PF07714.17 RLN88618.1 - 1.8e-42 145.5 0.0 2.7e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN88618.1 - 2.3e-38 132.1 0.0 3.5e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pectinesterase PF01095.19 RLN88618.1 - 0.16 10.6 0.2 0.42 9.3 0.2 1.6 2 0 0 2 2 2 0 Pectinesterase Glyco_hydro_28 PF00295.17 RLN88619.1 - 1.6e-15 57.0 5.1 2.1e-15 56.6 5.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Frag1 PF10277.9 RLN88619.1 - 9.6e-11 41.6 10.5 2.5e-10 40.3 10.5 1.6 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family BioY PF02632.14 RLN88619.1 - 0.018 15.1 7.6 0.018 15.1 7.6 2.8 2 2 1 3 3 3 0 BioY family BK_channel_a PF03493.18 RLN88620.1 - 4.9e-19 68.3 0.0 1.5e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 RLN88620.1 - 1.3e-11 44.2 9.4 5.1e-11 42.4 8.5 2.5 2 1 0 2 2 2 1 Ion channel Lig_chan PF00060.26 RLN88620.1 - 0.0005 19.9 0.4 0.0013 18.5 0.4 1.7 1 0 0 1 1 1 1 Ligand-gated ion channel TrkA_N PF02254.18 RLN88620.1 - 0.00064 20.0 0.5 0.62 10.3 0.1 2.5 2 0 0 2 2 2 2 TrkA-N domain DUF4501 PF14946.6 RLN88620.1 - 0.13 12.4 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) Capsule_synth PF05159.14 RLN88620.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Capsule polysaccharide biosynthesis protein DUF998 PF06197.13 RLN88620.1 - 0.43 10.2 7.3 0.17 11.5 2.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF998) Ribosomal_L13 PF00572.18 RLN88621.1 - 2.3e-53 179.7 0.0 2.8e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 DUF1168 PF06658.12 RLN88622.1 - 2.8e-14 53.1 35.0 1.8e-11 44.0 0.8 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1168) Rrn6 PF10214.9 RLN88622.1 - 0.0023 16.5 5.1 0.0024 16.5 5.1 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Borrelia_P83 PF05262.11 RLN88622.1 - 0.73 8.3 13.8 0.91 7.9 13.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Ku_C PF03730.14 RLN88622.1 - 2.6 8.8 9.9 5.6 7.7 9.9 1.5 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm DDRGK PF09756.9 RLN88622.1 - 2.6 7.6 16.9 3.7 7.1 16.9 1.3 1 0 0 1 1 1 0 DDRGK domain ATP11 PF06644.11 RLN88622.1 - 4.5 7.0 11.3 6.1 6.5 11.3 1.3 1 0 0 1 1 1 0 ATP11 protein U79_P34 PF03064.16 RLN88622.1 - 6.5 6.0 11.4 8.6 5.6 11.4 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF2431 PF10354.9 RLN88623.1 - 2.1e-38 132.2 0.0 2.8e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) CH_2 PF06294.11 RLN88624.1 - 3.5e-21 75.1 0.2 1e-20 73.6 0.2 1.9 1 0 0 1 1 1 1 CH-like domain in sperm protein ADK PF00406.22 RLN88624.1 - 2.1e-09 37.6 0.0 4.7e-08 33.3 0.0 3.0 3 0 0 3 3 3 1 Adenylate kinase AAA_17 PF13207.6 RLN88624.1 - 0.0019 18.7 2.7 0.034 14.6 0.0 4.1 4 0 0 4 4 4 1 AAA domain CH PF00307.31 RLN88624.1 - 0.026 14.7 0.1 0.07 13.3 0.1 1.8 1 0 0 1 1 1 0 Calponin homology (CH) domain Hydin_ADK PF17213.3 RLN88624.1 - 0.035 14.4 0.0 0.035 14.4 0.0 3.6 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 RLN88624.1 - 0.055 13.6 3.0 4.1 7.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 RLN88624.1 - 0.12 13.0 0.1 1.6 9.3 0.0 3.1 3 1 0 3 3 3 0 AAA domain AAA PF00004.29 RLN88624.1 - 0.14 12.6 0.3 7.6 7.0 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) YyzF PF14116.6 RLN88624.1 - 0.62 10.1 2.7 5.6 7.1 0.0 3.6 3 0 0 3 3 3 0 YyzF-like protein DUF641 PF04859.12 RLN88624.1 - 4.4 7.6 12.1 0.32 11.3 5.0 2.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) YchF-GTPase_C PF06071.13 RLN88625.1 - 3.1e-66 219.6 3.5 3.2e-37 126.6 0.5 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF933) Glyco_hydro_72 PF03198.14 RLN88625.1 - 1.5e-37 129.6 3.6 7.5e-26 91.1 0.4 2.3 2 0 0 2 2 2 2 Glucanosyltransferase MMR_HSR1 PF01926.23 RLN88625.1 - 2.1e-36 124.5 0.0 9.1e-18 64.4 0.0 3.0 2 1 1 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN88625.1 - 1.9e-13 50.3 0.0 1.3e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B MeaB PF03308.16 RLN88625.1 - 8.1e-06 25.0 0.0 0.11 11.5 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 RLN88625.1 - 0.00017 22.1 0.0 1.1 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 RLN88625.1 - 0.00058 19.7 0.0 2 8.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.27 RLN88625.1 - 0.00069 20.1 0.0 2.4 8.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter TGS PF02824.21 RLN88625.1 - 0.00082 19.4 0.1 0.18 11.9 0.0 3.0 2 0 0 2 2 2 1 TGS domain Dynamin_N PF00350.23 RLN88625.1 - 0.029 14.4 0.0 18 5.3 0.0 3.1 2 1 1 3 3 3 0 Dynamin family AAA_lid_11 PF18198.1 RLN88625.1 - 0.066 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain EGF_alliinase PF04863.13 RLN88625.1 - 0.43 11.0 12.1 1.4 9.3 12.1 2.0 1 0 0 1 1 1 0 Alliinase EGF-like domain AAA_6 PF12774.7 RLN88626.1 - 7.2e-136 452.4 0.0 6.1e-132 439.5 0.0 3.4 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 RLN88626.1 - 4.9e-91 304.7 0.0 9.9e-91 303.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 DHC_N2 PF08393.13 RLN88626.1 - 1.7e-89 300.7 0.3 1.7e-89 300.7 0.3 2.8 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 RLN88626.1 - 1.1e-76 258.0 0.0 7.7e-76 255.2 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 RLN88626.1 - 1.9e-75 252.8 1.2 6.3e-75 251.1 0.5 2.3 2 0 0 2 2 2 1 ATP-binding dynein motor region MT PF12777.7 RLN88626.1 - 5.9e-72 242.6 12.2 1e-71 241.8 12.2 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 RLN88626.1 - 5e-60 202.1 0.4 5.7e-56 188.9 0.0 3.8 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RLN88626.1 - 1e-48 165.3 0.1 1.4e-47 161.6 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RLN88626.1 - 7.2e-34 116.4 0.0 3.1e-33 114.4 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 RLN88626.1 - 2e-24 85.7 0.6 1.9e-23 82.5 0.4 2.9 2 0 0 2 2 1 1 AAA+ lid domain Kelch_5 PF13854.6 RLN88626.1 - 4e-21 74.6 0.4 2e-05 24.4 0.0 4.9 4 0 0 4 4 4 4 Kelch motif AAA_5 PF07728.14 RLN88626.1 - 6.4e-21 74.8 0.6 6e-08 32.8 0.0 6.7 7 1 0 7 7 6 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 RLN88626.1 - 8.9e-19 67.9 4.7 2.6e-18 66.4 4.7 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Kelch_6 PF13964.6 RLN88626.1 - 1e-17 63.7 3.8 2.3e-06 27.7 0.0 5.5 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 RLN88626.1 - 4.1e-15 55.6 3.1 6.5e-08 32.7 0.0 4.3 4 0 0 4 4 3 3 Galactose oxidase, central domain Filamin PF00630.19 RLN88626.1 - 1.3e-14 54.9 0.0 3.2e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Filamin/ABP280 repeat Kelch_4 PF13418.6 RLN88626.1 - 2.4e-10 40.2 12.1 0.00012 22.0 0.0 5.2 6 0 0 6 6 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 RLN88626.1 - 4.2e-10 39.0 5.6 8.9e-05 22.0 0.0 4.2 4 0 0 4 4 3 2 Kelch motif AAA_16 PF13191.6 RLN88626.1 - 4.2e-08 33.8 0.5 0.37 11.2 0.0 5.9 6 0 0 6 6 4 1 AAA ATPase domain Kelch_2 PF07646.15 RLN88626.1 - 1.2e-07 31.4 8.4 0.0029 17.5 0.0 4.9 5 0 0 5 5 4 2 Kelch motif TIG PF01833.24 RLN88626.1 - 1.3e-06 28.3 1.4 5.5e-06 26.4 0.5 2.3 2 0 0 2 2 2 1 IPT/TIG domain AAA_18 PF13238.6 RLN88626.1 - 1.7e-05 25.3 4.2 5.4 7.6 0.0 6.0 6 0 0 6 6 5 0 AAA domain AAA_22 PF13401.6 RLN88626.1 - 2.1e-05 24.8 1.0 6.8 7.0 0.0 4.9 5 0 0 5 5 3 0 AAA domain AAA_19 PF13245.6 RLN88626.1 - 3.5e-05 24.2 0.2 0.058 13.7 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 RLN88626.1 - 0.00024 21.3 0.2 0.57 10.3 0.0 4.5 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 RLN88626.1 - 0.00038 20.9 3.6 3.2 8.2 0.0 4.9 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) Invasin_D3 PF09134.10 RLN88626.1 - 0.0005 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Invasin, domain 3 AAA_30 PF13604.6 RLN88626.1 - 0.0032 17.2 0.4 16 5.1 0.1 3.8 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 RLN88626.1 - 0.013 15.8 0.1 4.2 7.6 0.0 3.4 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 RLN88626.1 - 0.013 15.9 0.3 24 5.4 0.0 3.7 3 0 0 3 3 3 0 RNA helicase T2SSE PF00437.20 RLN88626.1 - 0.032 13.3 0.9 0.65 9.0 0.0 3.0 4 0 0 4 4 3 0 Type II/IV secretion system protein YtkA PF13115.6 RLN88626.1 - 0.39 11.4 1.7 1.1 10.0 0.0 2.5 2 0 0 2 2 1 0 YtkA-like GGDEF PF00990.21 RLN88626.1 - 0.42 10.3 3.0 3.7 7.3 0.0 2.6 2 0 0 2 2 2 0 Diguanylate cyclase, GGDEF domain SRP54 PF00448.22 RLN88626.1 - 2.9 7.5 5.1 6.3 6.4 0.1 3.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain adh_short PF00106.25 RLN88627.1 - 4.5e-32 111.1 0.1 1.3e-28 99.9 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN88627.1 - 1.2e-20 74.1 0.1 2.1e-20 73.3 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN88627.1 - 1.8e-09 37.8 0.0 2.6e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN88627.1 - 4.9e-06 26.2 0.1 6e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 RLN88627.1 - 0.0046 16.3 0.0 0.0066 15.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 RLN88628.1 - 3.5e-34 118.0 0.2 4.3e-30 104.6 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN88628.1 - 3.1e-20 72.7 0.1 7.9e-20 71.4 0.0 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN88628.1 - 3.5e-10 40.1 0.0 5.1e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN88628.1 - 0.00089 18.8 0.1 0.0012 18.4 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 RLN88628.1 - 0.0022 17.3 0.0 0.0031 16.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 RLN88628.1 - 0.056 12.8 0.1 0.073 12.5 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 RLN88628.1 - 0.19 11.6 0.1 0.3 11.0 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_S10 PF00450.22 RLN88629.1 - 3.5e-111 372.6 0.0 4.1e-111 372.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Pkinase_Tyr PF07714.17 RLN88630.1 - 1.1e-83 280.5 0.0 5.2e-42 143.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN88630.1 - 4e-83 278.8 0.0 1.9e-46 158.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ank_4 PF13637.6 RLN88630.1 - 1.5e-25 89.2 0.5 6.9e-09 36.1 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN88630.1 - 6.6e-21 74.7 0.0 9.5e-11 42.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN88630.1 - 7.1e-15 54.9 0.8 2.8e-08 33.8 0.1 3.6 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN88630.1 - 1.8e-12 47.1 0.2 0.00076 19.8 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat FYVE PF01363.21 RLN88630.1 - 5.8e-12 45.6 18.3 2.4e-11 43.6 18.3 1.9 1 1 0 1 1 1 1 FYVE zinc finger Ank_3 PF13606.6 RLN88630.1 - 2.4e-11 42.8 0.0 0.03 14.8 0.0 4.2 4 0 0 4 4 3 3 Ankyrin repeat Kdo PF06293.14 RLN88630.1 - 3.7e-05 23.2 0.1 0.14 11.5 0.1 2.7 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN88630.1 - 0.00024 21.1 0.6 0.74 9.7 0.0 3.0 3 0 0 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN88630.1 - 0.0035 16.4 0.0 0.52 9.2 0.0 3.5 3 1 0 3 3 3 1 Haspin like kinase domain Pkinase_fungal PF17667.1 RLN88630.1 - 0.0048 15.7 0.1 0.18 10.6 0.0 2.8 3 0 0 3 3 3 1 Fungal protein kinase FCD PF07729.12 RLN88630.1 - 0.019 15.4 2.4 0.12 12.9 0.1 2.8 2 0 0 2 2 2 0 FCD domain ABC1 PF03109.16 RLN88630.1 - 0.12 12.6 0.0 0.9 9.7 0.0 2.4 2 0 0 2 2 2 0 ABC1 family FYVE_2 PF02318.16 RLN88630.1 - 0.47 10.7 10.2 1.3 9.3 10.2 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger START PF01852.19 RLN88631.1 - 0.0033 16.8 0.1 0.005 16.3 0.1 1.3 1 0 0 1 1 1 1 START domain ABC_membrane PF00664.23 RLN88632.1 - 1.2e-23 84.2 14.4 1.5e-23 83.8 14.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN88632.1 - 3e-07 31.0 0.2 6.1e-07 30.0 0.2 1.5 1 0 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 RLN88632.1 - 0.00015 21.9 0.6 0.00032 20.8 0.6 1.5 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 RLN88632.1 - 0.00042 20.3 0.1 0.00083 19.3 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 RLN88632.1 - 0.0023 17.4 0.1 0.004 16.6 0.1 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 RLN88632.1 - 0.0062 16.2 0.1 0.0099 15.5 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 RLN88632.1 - 0.0066 16.2 0.2 0.014 15.2 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 RLN88632.1 - 0.011 15.8 0.3 0.026 14.6 0.3 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 RLN88632.1 - 0.017 15.5 0.7 0.23 11.8 0.5 2.4 1 1 1 2 2 2 0 AAA ATPase domain AIG1 PF04548.16 RLN88632.1 - 0.023 14.0 0.2 0.041 13.2 0.2 1.4 1 0 0 1 1 1 0 AIG1 family Zeta_toxin PF06414.12 RLN88632.1 - 0.077 12.3 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.13 RLN88632.1 - 0.099 11.8 0.1 0.26 10.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 RLN88632.1 - 0.16 12.5 0.4 0.4 11.2 0.4 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RLN88632.1 - 0.16 12.2 0.1 0.32 11.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 RLN88632.1 - 0.18 10.8 0.5 0.65 9.0 0.4 1.8 1 1 1 2 2 2 0 Type II/IV secretion system protein DUF2273 PF10031.9 RLN88632.1 - 5.7 7.0 8.9 7.7 6.6 2.8 2.9 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) AAA_25 PF13481.6 RLN88633.1 - 0.00093 18.8 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 RLN88633.1 - 0.042 13.7 0.0 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_10 PF12846.7 RLN88633.1 - 0.043 12.7 0.0 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_5 PF07728.14 RLN88633.1 - 0.11 12.4 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Y_phosphatase PF00102.27 RLN88633.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase WW PF00397.26 RLN88634.1 - 2.1e-44 149.2 40.7 1.6e-08 34.5 0.7 7.1 7 0 0 7 7 7 6 WW domain IQ PF00612.27 RLN88634.1 - 2.1e-25 86.1 48.5 0.0013 18.4 1.7 10.9 11 0 0 11 11 10 9 IQ calmodulin-binding motif LRR_4 PF12799.7 RLN88634.1 - 1.6e-13 50.6 3.4 0.9 10.1 0.1 7.5 4 1 3 8 8 8 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RLN88634.1 - 5.2e-12 44.8 10.9 0.19 11.9 0.0 10.3 11 0 0 11 11 11 3 Leucine Rich repeat PQQ PF01011.21 RLN88634.1 - 3.8e-05 23.4 2.8 0.48 10.4 0.1 4.8 5 0 0 5 5 5 1 PQQ enzyme repeat Glyco_hyd_101C PF17451.2 RLN88634.1 - 0.00017 21.8 11.6 0.18 12.1 0.4 5.1 5 1 0 5 5 5 2 Glycosyl hydrolase 101 beta sandwich domain LRR_1 PF00560.33 RLN88634.1 - 0.0023 18.2 11.7 67 4.6 0.2 8.1 8 1 0 8 8 8 0 Leucine Rich Repeat DUF2913 PF11140.8 RLN88634.1 - 0.019 14.7 2.1 0.074 12.8 2.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) Spc24 PF08286.11 RLN88634.1 - 0.52 10.6 7.2 6 7.2 3.6 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 ADIP PF11559.8 RLN88634.1 - 4.3 7.4 21.5 3.1 7.9 8.0 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2423 PF10338.9 RLN88634.1 - 6.4 7.1 7.5 2.6 8.3 3.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) Aldedh PF00171.22 RLN88635.1 - 4.6e-77 259.5 0.1 5.1e-77 259.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 RLN88635.1 - 0.02 14.4 0.0 0.45 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Kinesin PF00225.23 RLN88636.1 - 5.9e-41 140.5 3.8 9.1e-33 113.6 2.5 3.2 2 1 0 2 2 2 2 Kinesin motor domain SlyX PF04102.12 RLN88636.1 - 0.033 14.8 0.2 0.033 14.8 0.2 3.2 2 1 1 3 3 3 0 SlyX CorA PF01544.18 RLN88636.1 - 0.22 10.8 4.2 3.3 6.9 0.1 2.5 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein LUC7 PF03194.15 RLN88636.1 - 0.28 10.8 7.2 6.6 6.3 7.2 2.3 1 1 0 1 1 1 0 LUC7 N_terminus TMPIT PF07851.13 RLN88636.1 - 0.36 10.0 3.4 6.1 6.0 0.1 2.8 3 0 0 3 3 3 0 TMPIT-like protein SHE3 PF17078.5 RLN88636.1 - 2.3 7.9 5.8 7.5 6.2 0.4 2.7 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Med9 PF07544.13 RLN88636.1 - 4.2 7.5 6.3 10 6.3 0.1 2.8 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Lebercilin PF15619.6 RLN88636.1 - 4.3 7.0 13.1 4.3 6.9 0.4 2.9 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease UPF0139 PF03669.13 RLN88637.1 - 5e-24 84.0 0.1 1.1e-23 82.8 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0139) CBP_BcsQ PF06564.12 RLN88637.1 - 0.042 13.3 0.3 0.074 12.5 0.3 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ Myosin_N PF02736.19 RLN88638.1 - 5e-06 26.2 0.1 1.7e-05 24.5 0.1 1.8 1 1 0 1 1 1 1 Myosin N-terminal SH3-like domain Pyr_redox_2 PF07992.14 RLN88639.1 - 3e-13 49.6 0.5 9.1e-12 44.8 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RLN88639.1 - 0.00017 21.7 0.0 0.00037 20.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 RLN88639.1 - 0.00026 20.4 0.1 0.0011 18.2 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 RLN88639.1 - 0.0074 16.7 0.1 3.3 8.2 0.0 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding Thi4 PF01946.17 RLN88639.1 - 0.0098 15.2 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.20 RLN88639.1 - 0.035 14.2 0.1 50 3.9 0.0 3.2 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 RLN88639.1 - 0.058 14.0 0.2 1.7 9.3 0.1 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2OG-FeII_Oxy_3 PF13640.6 RLN88640.1 - 7.7e-08 33.1 0.2 0.0016 19.3 0.0 2.7 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 RLN88641.1 - 2.9e-17 63.0 1.3 2.8e-12 47.1 0.8 2.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN88641.1 - 2.9e-12 45.6 2.9 0.047 14.2 0.0 5.0 4 0 0 4 4 4 4 Ankyrin repeat Gly_rich PF12810.7 RLN88641.1 - 5.5e-11 42.8 54.2 1.2e-10 41.8 54.2 1.5 1 0 0 1 1 1 1 Glycine rich protein Ank PF00023.30 RLN88641.1 - 6e-10 39.1 9.1 0.018 15.5 0.1 5.3 6 0 0 6 6 5 4 Ankyrin repeat EF-hand_1 PF00036.32 RLN88641.1 - 9.8e-10 37.3 0.0 0.0023 17.4 0.0 2.7 2 0 0 2 2 2 2 EF hand Ank_4 PF13637.6 RLN88641.1 - 1.4e-09 38.3 2.5 5.7e-06 26.8 0.2 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) EF-hand_8 PF13833.6 RLN88641.1 - 1e-08 34.9 0.1 8.3e-07 28.8 0.0 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 RLN88641.1 - 1.4e-08 35.1 0.1 5.1e-08 33.3 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair Ank_5 PF13857.6 RLN88641.1 - 4e-08 33.4 2.0 0.00044 20.5 0.0 4.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) EF-hand_5 PF13202.6 RLN88641.1 - 2.9e-07 29.7 0.2 0.03 13.8 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN88641.1 - 1.9e-06 27.3 0.0 0.048 13.6 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain WW PF00397.26 RLN88641.1 - 3.1e-06 27.2 5.9 0.031 14.4 0.3 3.6 4 0 0 4 4 3 2 WW domain FAP206 PF12018.8 RLN88641.1 - 0.0075 15.8 0.5 0.015 14.8 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function SUIM_assoc PF16619.5 RLN88641.1 - 3.3 7.8 5.4 12 6.1 5.4 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Pkinase PF00069.25 RLN88642.1 - 1.3e-12 47.7 0.0 1.8e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Dimer_Tnp_hAT PF05699.14 RLN88645.1 - 1.5e-16 60.0 0.0 3.4e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 RLN88645.1 - 1.9e-05 24.6 0.1 5.6e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) DBD_Tnp_Hermes PF10683.9 RLN88645.1 - 3.3e-05 23.5 0.2 0.00012 21.7 0.0 2.0 2 0 0 2 2 2 1 Hermes transposase DNA-binding domain DUF4371 PF14291.6 RLN88645.1 - 0.00063 19.5 0.0 0.0036 17.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) RWP-RK PF02042.15 RLN88646.1 - 3e-17 62.3 0.3 5.6e-17 61.4 0.3 1.5 1 0 0 1 1 1 1 RWP-RK domain WD40 PF00400.32 RLN88647.1 - 3.3e-13 49.9 14.3 0.0021 18.9 0.0 6.4 5 1 0 5 5 5 3 WD domain, G-beta repeat RhoGAP PF00620.27 RLN88647.1 - 6.7e-09 35.7 0.0 2.2e-05 24.4 0.1 2.3 2 0 0 2 2 2 2 RhoGAP domain ANAPC4_WD40 PF12894.7 RLN88647.1 - 2.8e-06 27.5 0.0 0.76 10.1 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cwf_Cwc_15 PF04889.12 RLN88648.1 - 0.023 14.5 11.9 0.026 14.2 11.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 RLN88648.1 - 0.12 11.5 17.9 0.12 11.5 17.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.11 RLN88648.1 - 0.13 12.3 4.0 0.13 12.3 4.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 RLN88648.1 - 0.18 11.1 15.8 0.18 11.1 15.8 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 RLN88648.1 - 0.35 9.1 5.2 0.32 9.2 5.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Utp14 PF04615.13 RLN88648.1 - 0.45 9.0 6.6 0.52 8.8 6.6 1.1 1 0 0 1 1 1 0 Utp14 protein BUD22 PF09073.10 RLN88648.1 - 1.8 7.9 7.5 1.7 7.9 7.5 1.1 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.13 RLN88648.1 - 4.6 7.1 8.6 4.8 7.0 8.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region GCIP PF13324.6 RLN88648.1 - 8.4 5.9 8.7 8.6 5.9 8.7 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RRN3 PF05327.11 RLN88648.1 - 9 4.7 8.7 8.9 4.7 8.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 RLN88648.1 - 9 4.4 9.4 8.7 4.4 9.4 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 RLN88648.1 - 9.1 5.9 6.8 13 5.5 6.8 1.3 1 0 0 1 1 1 0 FAM176 family Methyltr_RsmB-F PF01189.17 RLN88649.1 - 6.5e-17 61.8 0.6 1.7e-15 57.2 0.6 2.8 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F RXT2_N PF08595.11 RLN88649.1 - 0.058 13.4 4.5 0.28 11.2 3.7 2.4 3 0 0 3 3 3 0 RXT2-like, N-terminal Pro-NT_NN PF07421.11 RLN88649.1 - 0.093 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor Herpes_UL56 PF04534.12 RLN88649.1 - 0.12 11.9 1.7 0.24 10.9 1.7 1.4 1 0 0 1 1 1 0 Herpesvirus UL56 protein Coilin_N PF15862.5 RLN88649.1 - 3.4 7.5 9.8 0.17 11.7 0.5 2.3 2 0 0 2 2 2 0 Coilin N-terminus FYDLN_acid PF09538.10 RLN88649.1 - 8.1 7.2 13.7 0.8 10.4 5.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Vpu PF00558.19 RLN88650.1 - 0.18 11.6 0.1 0.57 10.0 0.1 1.8 1 0 0 1 1 1 0 Vpu protein ECR1_N PF14382.6 RLN88651.1 - 1.4e-12 47.2 0.1 3.5e-12 45.9 0.1 1.8 1 1 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.9 RLN88651.1 - 2.8e-09 37.5 0.7 0.00038 21.0 0.0 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 TPR_1 PF00515.28 RLN88652.1 - 3.9e-17 61.2 2.1 6.7e-07 28.9 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN88652.1 - 2.1e-13 49.3 5.8 4.4e-07 29.5 0.0 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 RLN88652.1 - 4e-08 33.3 0.9 1.2e-07 31.8 0.4 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN88652.1 - 5.7e-08 32.3 1.6 0.0016 18.0 0.1 2.8 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 RLN88652.1 - 8.3e-06 25.6 0.1 0.028 14.6 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN88652.1 - 1.2e-05 25.3 0.1 0.41 11.1 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN88652.1 - 8.8e-05 23.1 2.0 0.0002 21.9 1.2 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN88652.1 - 0.001 19.3 3.3 0.37 11.1 0.1 3.4 1 1 0 2 2 2 1 Tetratricopeptide repeat MAS20 PF02064.15 RLN88652.1 - 0.011 15.8 4.8 1.2 9.2 3.2 2.6 2 0 0 2 2 2 0 MAS20 protein import receptor TPR_7 PF13176.6 RLN88652.1 - 0.02 14.9 0.4 12 6.1 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN88652.1 - 0.032 14.3 0.2 0.1 12.7 0.2 1.9 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 RLN88652.1 - 0.034 15.0 7.0 0.14 13.1 0.1 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN88652.1 - 0.073 13.0 3.0 0.51 10.3 0.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN88652.1 - 5 7.7 10.1 1 9.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat EXS PF03124.14 RLN88653.1 - 1.2e-59 202.3 13.4 1.7e-59 201.8 13.4 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 RLN88653.1 - 3.3e-15 56.9 2.9 2.2e-07 31.1 0.1 3.0 1 1 2 3 3 3 3 SPX domain Angiomotin_C PF12240.8 RLN88653.1 - 0.014 15.0 0.5 0.027 14.1 0.5 1.4 1 0 0 1 1 1 0 Angiomotin C terminal PNP_UDP_1 PF01048.20 RLN88654.1 - 5.3e-44 150.2 0.0 7e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Snf7 PF03357.21 RLN88655.1 - 2.7e-15 56.4 9.5 3.7e-15 56.0 9.5 1.2 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 RLN88655.1 - 0.002 18.1 1.2 0.0026 17.7 1.2 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Cytochrom_B562 PF07361.11 RLN88655.1 - 0.93 10.2 11.1 0.54 11.0 3.0 3.0 2 2 1 3 3 3 0 Cytochrome b562 RNase_PH PF01138.21 RLN88656.1 - 4.1e-33 114.7 0.0 4.2e-19 69.4 0.0 2.5 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RLN88656.1 - 2.5e-14 53.0 0.1 4.6e-09 36.2 0.0 2.6 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 S1 PF00575.23 RLN88656.1 - 1.2e-09 38.3 0.1 7.2e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 S1 RNA binding domain KH_1 PF00013.29 RLN88656.1 - 1.5e-08 34.4 0.0 3.8e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 KH domain DUF2076 PF09849.9 RLN88656.1 - 0.011 15.8 0.8 0.011 15.8 0.8 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) KH_2 PF07650.17 RLN88656.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 KH domain KH_5 PF13184.6 RLN88656.1 - 0.071 13.2 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 NusA-like KH domain Ribosomal_60s PF00428.19 RLN88656.1 - 2.1 9.0 11.1 2.5 8.7 4.9 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein TRP PF06011.12 RLN88657.1 - 4.4e-25 88.3 5.0 6.4e-25 87.8 5.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel Sdh_cyt PF01127.22 RLN88657.1 - 3.6 7.7 17.8 0.11 12.6 8.8 2.3 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Glyco_hydro81C PF17652.1 RLN88658.1 - 1.6e-107 359.8 0.2 2.4e-107 359.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 RLN88658.1 - 2.3e-45 155.2 2.0 3.4e-45 154.6 2.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain TetR_C_31 PF17940.1 RLN88658.1 - 0.1 12.8 0.0 0.48 10.6 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ZapB PF06005.12 RLN88660.1 - 0.024 15.1 1.1 0.024 15.1 1.1 6.7 5 1 1 6 6 6 0 Cell division protein ZapB IF4E PF01652.18 RLN88661.1 - 4.7e-13 49.2 0.0 7.5e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF3280 PF11684.8 RLN88661.1 - 0.076 13.4 0.9 2.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2380) TPR_2 PF07719.17 RLN88662.1 - 0.0031 17.5 4.6 0.12 12.5 0.8 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat LUC7 PF03194.15 RLN88662.1 - 0.0074 16.0 10.9 0.49 10.0 0.1 3.3 3 0 0 3 3 3 2 LUC7 N_terminus DUF2379 PF09543.10 RLN88662.1 - 0.12 12.6 3.9 0.15 12.3 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2379) C2-C2_1 PF11618.8 RLN88663.1 - 2.9e-37 127.9 0.0 1.2e-35 122.7 0.0 2.6 2 0 0 2 2 2 1 First C2 domain of RPGR-interacting protein 1 EF-hand_8 PF13833.6 RLN88663.1 - 9.4e-13 47.8 14.3 0.0015 18.3 0.0 8.8 10 0 0 10 10 10 3 EF-hand domain pair EF-hand_7 PF13499.6 RLN88663.1 - 9.1e-10 38.9 6.3 1.9 9.0 0.0 8.9 9 0 0 9 9 9 3 EF-hand domain pair EF-hand_6 PF13405.6 RLN88663.1 - 1.6e-08 33.8 6.1 0.093 12.7 0.0 7.6 9 0 0 9 9 9 2 EF-hand domain EF-hand_1 PF00036.32 RLN88663.1 - 1.3e-05 24.4 1.4 18 5.2 0.0 7.0 7 0 0 7 7 7 0 EF hand C2 PF00168.30 RLN88663.1 - 3.1e-05 24.2 0.0 0.035 14.4 0.0 2.6 2 0 0 2 2 2 2 C2 domain EF-hand_11 PF08976.11 RLN88663.1 - 0.00019 22.2 0.0 0.12 13.3 0.0 4.4 4 0 0 4 4 4 1 EF-hand domain FGAR-AT_linker PF18072.1 RLN88663.1 - 0.018 15.5 0.0 61 4.3 0.0 4.6 4 0 0 4 4 4 0 Formylglycinamide ribonucleotide amidotransferase linker domain HEPN_Toprim_N PF18871.1 RLN88663.1 - 0.16 11.8 0.5 0.59 10.0 0.0 2.1 2 0 0 2 2 2 0 HEPN/Toprim N-terminal domain 1 VTC PF09359.10 RLN88663.1 - 2.2 7.6 6.6 4.2 6.7 6.6 1.4 1 0 0 1 1 1 0 VTC domain DEAD PF00270.29 RLN88664.1 - 2.6e-16 59.9 0.0 5.8e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN88664.1 - 6.1e-15 55.5 0.0 3.6e-14 53.1 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 RLN88664.1 - 1.2e-10 41.9 1.1 4.6e-10 40.1 1.1 2.1 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 RLN88664.1 - 0.00095 19.2 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RLN88664.1 - 0.065 13.5 0.0 0.33 11.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain Trypsin_2 PF13365.6 RLN88665.1 - 1.8e-17 64.6 0.7 2.8e-17 64.0 0.7 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S46 PF10459.9 RLN88665.1 - 0.038 12.6 0.1 0.038 12.6 0.1 1.4 2 0 0 2 2 2 0 Peptidase S46 WD40 PF00400.32 RLN88666.1 - 1e-19 70.5 1.1 1.2e-08 35.5 0.2 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN88666.1 - 7.2e-07 29.4 0.4 0.0015 18.8 0.0 2.7 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RLN88666.1 - 0.00012 21.5 0.0 0.1 11.9 0.0 2.1 1 1 1 2 2 2 2 WD40-like domain DAGK_cat PF00781.24 RLN88666.1 - 0.00057 19.5 0.6 0.0011 18.5 0.1 1.7 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain eIF2A PF08662.11 RLN88666.1 - 0.022 14.7 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 RLN88666.1 - 0.14 11.0 0.8 0.57 9.1 0.3 1.9 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain PHD PF00628.29 RLN88667.1 - 7.1e-12 45.0 28.1 1.2e-08 34.7 5.5 4.1 4 0 0 4 4 4 2 PHD-finger zf-HC5HC2H PF13771.6 RLN88667.1 - 1.8e-08 34.5 6.5 0.00083 19.6 1.0 2.8 2 1 0 2 2 2 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 RLN88667.1 - 0.00036 20.7 10.7 0.032 14.4 2.2 2.8 2 1 0 2 2 2 2 PHD-zinc-finger like domain FANCL_C PF11793.8 RLN88667.1 - 0.0028 17.8 6.5 0.52 10.5 2.2 3.0 2 0 0 2 2 2 2 FANCL C-terminal domain zf-PHD-like PF15446.6 RLN88667.1 - 0.01 15.5 19.2 0.15 11.7 2.6 3.7 3 1 0 3 3 3 0 PHD/FYVE-zinc-finger like domain Gpi16 PF04113.14 RLN88668.1 - 3.1e-107 359.3 0.0 3.4e-105 352.6 0.0 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component CCT PF06203.14 RLN88669.1 - 1.9e-16 59.8 14.8 3.8e-16 58.8 14.8 1.5 1 0 0 1 1 1 1 CCT motif CCT_2 PF09425.10 RLN88669.1 - 0.069 13.1 4.8 0.18 11.7 4.8 1.7 1 0 0 1 1 1 0 Divergent CCT motif MFS_1 PF07690.16 RLN88670.1 - 4.7e-26 91.6 24.3 4.7e-26 91.6 24.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 RLN88670.1 - 1.2e-10 40.3 6.3 2.3e-10 39.4 0.0 3.5 1 1 2 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 RLN88670.1 - 2.3e-10 39.9 20.5 7.5e-10 38.3 13.9 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter ADK PF00406.22 RLN88671.1 - 9e-88 292.0 0.0 1.1e-42 145.7 0.0 2.4 2 0 0 2 2 2 2 Adenylate kinase DUF4821 PF16092.5 RLN88671.1 - 5e-74 249.2 0.0 1.7e-69 234.4 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4821) AAA_17 PF13207.6 RLN88671.1 - 9.2e-47 158.9 0.0 2.2e-22 79.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 RLN88671.1 - 6.1e-13 49.4 0.0 2.9e-05 24.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 RLN88671.1 - 6.5e-10 39.3 0.0 0.0011 19.1 0.0 4.0 3 1 1 4 4 4 2 AAA domain ADK_lid PF05191.14 RLN88671.1 - 2.6e-07 30.5 0.0 0.031 14.2 0.0 2.9 2 0 0 2 2 2 2 Adenylate kinase, active site lid Hydin_ADK PF17213.3 RLN88671.1 - 1.1e-05 25.8 4.2 1.1 9.5 0.0 4.6 3 2 2 5 5 5 2 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 RLN88671.1 - 6.8e-05 22.7 0.0 0.39 10.4 0.0 2.6 2 0 0 2 2 2 2 Cytidylate kinase Pyr_redox_2 PF07992.14 RLN88671.1 - 8.7e-05 21.9 0.0 0.00062 19.1 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase OrfB_Zn_ribbon PF07282.11 RLN88672.1 - 5.7e-07 29.4 5.2 5.2e-06 26.3 5.2 2.3 1 1 0 1 1 1 1 Putative transposase DNA-binding domain Tetraspanin PF00335.20 RLN88673.1 - 3.2e-06 27.0 0.3 3.6e-06 26.9 0.3 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF4689 PF15755.5 RLN88673.1 - 0.19 11.3 0.7 0.24 11.0 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4689) DUF2892 PF11127.8 RLN88673.1 - 2.9 8.0 8.1 0.19 11.8 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2892) TraK PF06586.11 RLN88674.1 - 0.024 14.3 0.2 0.025 14.3 0.2 1.2 1 0 0 1 1 1 0 TraK protein Acyltransferase PF01553.21 RLN88675.1 - 6.9e-15 54.9 0.0 1.3e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase EF-hand_1 PF00036.32 RLN88675.1 - 8e-15 53.2 0.6 0.00045 19.6 0.0 3.8 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 RLN88675.1 - 8.6e-15 53.3 3.5 0.00016 21.4 0.2 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 RLN88675.1 - 3.1e-13 48.5 3.8 0.00029 20.2 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 RLN88675.1 - 2.7e-11 43.8 2.8 2.5e-05 24.6 1.1 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RLN88675.1 - 0.00013 21.7 3.2 0.72 9.7 0.2 4.0 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_4 PF12763.7 RLN88675.1 - 0.0052 16.7 3.0 0.77 9.7 0.1 2.9 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RLN88675.1 - 0.036 14.4 0.6 0.64 10.4 0.1 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region UDPG_MGDP_dh_N PF03721.14 RLN88676.1 - 6.9e-59 198.6 0.5 1.1e-58 198.0 0.5 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 RLN88676.1 - 1.5e-33 115.4 0.0 2.3e-31 108.3 0.0 2.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 RLN88676.1 - 5e-31 106.8 0.0 1.1e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 RLN88676.1 - 0.0037 17.5 0.0 0.032 14.4 0.0 2.6 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Thioredoxin PF00085.20 RLN88677.1 - 2.3e-08 34.0 0.0 4.2e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin ADK PF00406.22 RLN88678.1 - 7.4e-76 253.4 0.0 1.5e-43 148.5 0.0 2.5 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 RLN88678.1 - 6.3e-42 143.2 0.0 3.2e-22 79.4 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_33 PF13671.6 RLN88678.1 - 2.9e-13 50.2 0.5 0.00017 21.8 0.5 4.1 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 RLN88678.1 - 1e-12 48.8 0.0 4.2e-06 27.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain Hydin_ADK PF17213.3 RLN88678.1 - 4e-07 30.5 2.0 0.61 10.3 0.2 4.5 3 1 1 4 4 4 2 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 RLN88678.1 - 3.4e-05 23.7 0.0 0.013 15.3 0.0 3.0 3 1 0 3 3 3 1 Cytidylate kinase Zeta_toxin PF06414.12 RLN88678.1 - 0.0012 18.2 0.1 0.69 9.2 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA PF00004.29 RLN88678.1 - 0.0039 17.6 0.0 1.2 9.5 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.10 RLN88678.1 - 0.0061 16.1 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Thymidylate_kin PF02223.17 RLN88678.1 - 0.0061 16.3 0.0 16 5.2 0.0 3.7 3 0 0 3 3 3 0 Thymidylate kinase AAA_28 PF13521.6 RLN88678.1 - 0.0061 16.8 0.0 1.9 8.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 RLN88678.1 - 0.0076 16.6 0.5 3 8.2 0.0 3.1 3 0 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 RLN88678.1 - 0.012 15.9 0.0 11 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain ADK_lid PF05191.14 RLN88678.1 - 0.032 14.2 0.0 0.1 12.6 0.0 1.9 1 1 0 1 1 1 0 Adenylate kinase, active site lid RuvB_N PF05496.12 RLN88678.1 - 0.066 12.9 0.0 4.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 RLN88678.1 - 0.072 13.0 0.1 3 7.7 0.0 2.5 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.21 RLN88678.1 - 0.15 11.4 0.2 1.4 8.3 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI FACT-Spt16_Nlob PF14826.6 RLN88679.1 - 8.6e-37 126.4 0.2 6.1e-36 123.6 0.2 2.5 1 1 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 RLN88679.1 - 1.6e-32 112.9 0.0 2.4e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 SPT16 PF08644.11 RLN88679.1 - 4.9e-32 111.2 0.1 4.9e-32 111.2 0.1 2.3 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) EF-hand_6 PF13405.6 RLN88681.1 - 4.2e-10 38.7 0.0 0.00031 20.5 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RLN88681.1 - 5.7e-10 38.0 0.0 0.00022 20.6 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RLN88681.1 - 1e-09 38.7 0.1 2e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN88681.1 - 7e-06 25.3 0.0 0.043 13.3 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RLN88681.1 - 7.3e-05 22.5 0.1 0.00031 20.5 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain pair YqaJ PF09588.10 RLN88681.1 - 0.024 14.8 0.0 0.062 13.5 0.0 1.7 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain FlgN PF05130.12 RLN88681.1 - 1 9.9 6.1 35 4.9 3.5 2.7 3 0 0 3 3 3 0 FlgN protein 7tm_3 PF00003.22 RLN88682.1 - 6.1e-40 137.4 26.3 8.6e-40 136.9 26.3 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR CytochromB561_N PF09786.9 RLN88682.1 - 0.048 12.7 2.0 0.073 12.1 2.0 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal EF-hand_5 PF13202.6 RLN88683.1 - 2.4e-19 67.9 1.9 9.8e-07 28.0 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_1 PF00036.32 RLN88683.1 - 1.2e-17 62.0 1.5 1.3e-05 24.4 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 RLN88683.1 - 2.6e-17 61.2 2.4 4.5e-05 23.0 0.1 4.0 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 RLN88683.1 - 9.2e-14 51.7 2.7 2.5e-07 31.0 0.4 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 RLN88683.1 - 5.6e-09 35.7 0.1 0.017 14.9 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain pair ZZ PF00569.17 RLN88683.1 - 4.4e-05 23.2 17.0 0.0087 15.9 4.9 2.8 2 1 0 2 2 2 2 Zinc finger, ZZ type Dockerin_1 PF00404.18 RLN88683.1 - 0.0014 18.7 0.0 0.057 13.6 0.0 2.7 2 1 1 3 3 3 2 Dockerin type I domain SPARC_Ca_bdg PF10591.9 RLN88683.1 - 0.0017 18.6 0.0 0.042 14.2 0.0 2.3 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 RLN88683.1 - 0.1 12.5 0.0 5.1 7.0 0.0 2.6 2 0 0 2 2 2 0 EF hand zf-RING_4 PF14570.6 RLN88683.1 - 2.2 8.1 17.1 1.4 8.8 4.4 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain C1_1 PF00130.22 RLN88683.1 - 2.6 8.0 12.9 1.7 8.6 2.5 2.7 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) H_PPase PF03030.16 RLN88684.1 - 3.3e-254 845.4 35.2 4.2e-254 845.1 35.2 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase DIM PF08194.12 RLN88684.1 - 1.2 9.4 3.8 17 5.7 0.2 3.4 2 0 0 2 2 2 0 DIM protein Acyl-CoA_dh_1 PF00441.24 RLN88685.1 - 1.2e-42 145.7 1.9 1.5e-42 145.4 1.9 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RLN88685.1 - 7.5e-24 83.8 0.0 1.3e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RLN88685.1 - 3.5e-19 69.4 0.1 4.7e-19 69.0 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain zf-RING_UBOX PF13445.6 RLN88686.1 - 7.6e-05 22.7 7.4 0.00018 21.4 7.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RLN88686.1 - 0.00049 19.9 8.4 0.0016 18.3 8.5 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN88686.1 - 0.0011 18.8 9.9 0.0027 17.5 9.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN88686.1 - 0.0034 17.3 9.7 0.007 16.3 9.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain TEP1_N PF05386.11 RLN88686.1 - 0.018 14.6 0.0 0.065 12.8 0.0 1.9 1 0 0 1 1 1 0 TEP1 N-terminal domain zf-C3HC4_4 PF15227.6 RLN88686.1 - 0.025 14.8 10.9 0.054 13.7 10.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FlgN PF05130.12 RLN88686.1 - 0.027 15.0 1.5 0.027 15.0 1.5 6.7 3 1 3 6 6 3 0 FlgN protein zf-RING_6 PF14835.6 RLN88686.1 - 0.046 13.6 5.2 0.1 12.5 5.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Siva PF05458.12 RLN88686.1 - 0.079 12.6 3.8 0.26 11.0 3.8 1.9 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Shugoshin_N PF07558.11 RLN88686.1 - 1.3 8.9 12.3 4.2 7.3 1.5 5.0 3 1 1 4 4 4 0 Shugoshin N-terminal coiled-coil region TraF_2 PF13729.6 RLN88686.1 - 1.5 8.1 5.4 0.23 10.8 0.4 2.1 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein zf-RING_2 PF13639.6 RLN88686.1 - 1.9 8.9 10.1 4.3 7.7 10.1 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_10 PF16685.5 RLN88686.1 - 3.1 8.0 9.4 8 6.7 9.4 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 RLN88686.1 - 5 7.1 8.3 11 6.0 8.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 adh_short PF00106.25 RLN88688.1 - 1.1e-06 28.3 0.0 4.7e-06 26.2 0.0 1.9 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN88688.1 - 0.0013 18.3 0.0 0.004 16.7 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.8 RLN88688.1 - 0.0077 16.0 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.10 RLN88688.1 - 0.017 15.0 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 KR domain cNMP_binding PF00027.29 RLN88689.1 - 7.6e-19 67.6 0.1 2.2e-18 66.1 0.0 1.9 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN88689.1 - 1.4e-17 63.7 1.5 2.1e-17 63.2 1.5 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RLN88689.1 - 0.00028 20.8 0.4 0.00063 19.7 0.4 1.6 1 0 0 1 1 1 1 Ion channel adh_short PF00106.25 RLN88690.1 - 0.00015 21.3 0.0 0.00049 19.6 0.0 1.9 1 1 1 2 2 2 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.8 RLN88690.1 - 0.004 16.9 0.1 0.0065 16.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.25 RLN88691.1 - 1.6e-06 27.8 0.0 3.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN88691.1 - 0.0017 18.0 0.0 0.0089 15.6 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Ldh_1_N PF00056.23 RLN88691.1 - 0.013 15.6 0.1 0.027 14.6 0.1 1.5 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain KR PF08659.10 RLN88691.1 - 0.034 14.1 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 KR domain Eno-Rase_NADH_b PF12242.8 RLN88691.1 - 0.12 12.2 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Eno-Rase_NADH_b PF12242.8 RLN88692.1 - 0.071 12.9 0.3 0.13 12.0 0.3 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.25 RLN88692.1 - 0.16 11.4 0.9 1.6 8.2 1.4 2.1 1 1 1 2 2 2 0 short chain dehydrogenase CCDC53 PF10152.9 RLN88693.1 - 4.1e-44 150.7 4.8 9.4e-42 143.0 0.0 3.7 2 2 0 2 2 2 1 Subunit CCDC53 of WASH complex HECT PF00632.25 RLN88694.1 - 5e-09 36.1 0.0 8.8e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF659 PF04937.15 RLN88695.1 - 1.7e-05 24.7 0.1 4.7e-05 23.3 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) zf-BED PF02892.15 RLN88695.1 - 0.00044 20.2 0.1 0.28 11.3 0.0 2.5 2 0 0 2 2 2 2 BED zinc finger Nup54 PF13874.6 RLN88695.1 - 0.065 13.3 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF3929 PF13066.6 RLN88697.1 - 0.069 13.2 0.3 0.13 12.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) Acyl-CoA_dh_2 PF08028.11 RLN88698.1 - 0.72 10.1 6.6 1.3 9.3 6.6 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain M16C_assoc PF08367.11 RLN88698.1 - 5.8 6.0 9.7 3.6 6.6 7.8 1.6 2 0 0 2 2 2 0 Peptidase M16C associated VIT1 PF01988.19 RLN88699.1 - 0.24 11.2 4.6 0.54 10.1 4.6 1.7 1 1 0 1 1 1 0 VIT family DUF202 PF02656.15 RLN88699.1 - 1.2 9.7 0.0 1.2 9.7 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF202) HupE_UreJ_2 PF13795.6 RLN88700.1 - 0.0024 17.6 1.6 0.037 13.7 0.3 2.5 2 0 0 2 2 2 1 HupE / UreJ protein 4HBT PF03061.22 RLN88700.1 - 0.0026 18.1 0.8 2.8 8.4 0.2 2.5 2 0 0 2 2 2 2 Thioesterase superfamily HupE_UreJ PF04955.12 RLN88700.1 - 0.042 13.3 0.6 0.042 13.3 0.6 2.7 3 0 0 3 3 3 0 HupE / UreJ protein MerE PF05052.12 RLN88700.1 - 0.045 13.7 1.7 0.14 12.1 1.7 1.8 1 0 0 1 1 1 0 MerE protein HupE_UreJ PF04955.12 RLN88701.1 - 0.00019 21.0 6.5 0.00065 19.2 0.4 3.0 2 1 0 3 3 3 2 HupE / UreJ protein HupE_UreJ_2 PF13795.6 RLN88701.1 - 0.0011 18.7 6.1 0.034 13.8 0.4 2.7 2 1 1 3 3 3 2 HupE / UreJ protein MerE PF05052.12 RLN88701.1 - 0.025 14.5 4.1 0.1 12.5 4.1 2.1 1 0 0 1 1 1 0 MerE protein YtpI PF14007.6 RLN88701.1 - 0.037 14.1 0.4 0.037 14.1 0.4 2.6 2 1 0 2 2 2 0 YtpI-like protein Nuc_sug_transp PF04142.15 RLN88702.1 - 1.9e-22 79.8 10.3 2.9e-22 79.2 10.3 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 RLN88702.1 - 2.2e-07 30.4 5.3 2.2e-07 30.4 5.3 2.0 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 RLN88702.1 - 0.0014 18.8 14.6 0.0014 18.8 14.6 2.7 3 0 0 3 3 3 1 EamA-like transporter family BTB PF00651.31 RLN88703.1 - 0.00011 22.4 0.0 0.00022 21.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain SBE2 PF17076.5 RLN88704.1 - 0.87 7.7 4.2 1.2 7.3 4.2 1.2 1 0 0 1 1 1 0 SBE2, cell-wall formation Pkinase PF00069.25 RLN88705.1 - 1.8e-60 204.6 0.0 2e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN88705.1 - 5.9e-25 88.0 0.0 7e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN88705.1 - 8.6e-05 22.0 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN88705.1 - 0.00011 22.2 0.2 0.0022 18.0 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN88705.1 - 0.031 13.6 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 RLN88705.1 - 0.085 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Glyco_hydro_47 PF01532.20 RLN88706.1 - 3.5e-101 339.4 2.8 1e-68 232.3 0.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 Syntaxin PF00804.25 RLN88707.1 - 0.0031 17.2 2.8 0.95 9.1 0.0 2.3 2 0 0 2 2 2 2 Syntaxin Syntaxin_2 PF14523.6 RLN88707.1 - 0.032 14.6 2.4 0.066 13.6 0.8 2.1 2 0 0 2 2 2 0 Syntaxin-like protein SNARE PF05739.19 RLN88707.1 - 0.051 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 SNARE domain FliG_N PF14842.6 RLN88707.1 - 0.064 13.8 2.1 1.6 9.3 0.2 2.9 3 0 0 3 3 3 0 FliG N-terminal domain FUSC PF04632.12 RLN88707.1 - 7.8 4.9 7.6 12 4.3 7.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DHC_N2 PF08393.13 RLN88708.1 - 3.3e-96 322.8 13.9 3.3e-96 322.8 13.9 1.8 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Kelch_5 PF13854.6 RLN88708.1 - 1.2e-33 114.5 9.9 2.3e-09 37.0 0.1 6.8 6 0 0 6 6 6 6 Kelch motif AAA_6 PF12774.7 RLN88708.1 - 1.3e-31 109.8 1.3 1.6e-31 109.5 0.2 1.7 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region Kelch_4 PF13418.6 RLN88708.1 - 5.3e-30 103.2 15.7 1.4e-08 34.6 0.3 6.6 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 RLN88708.1 - 9.4e-28 95.6 8.9 2.4e-10 40.3 0.1 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 RLN88708.1 - 1e-26 91.9 14.5 1.4e-08 34.4 0.2 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 RLN88708.1 - 5.7e-24 83.4 12.2 1.3e-07 31.0 0.0 6.4 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 RLN88708.1 - 3.4e-23 81.4 17.6 2.7e-06 27.5 0.0 7.5 7 0 0 7 7 7 4 Galactose oxidase, central domain Filamin PF00630.19 RLN88708.1 - 3.6e-15 56.6 0.0 9.1e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Filamin/ABP280 repeat TIG PF01833.24 RLN88708.1 - 0.00017 21.6 0.1 0.00039 20.4 0.1 1.6 1 0 0 1 1 1 1 IPT/TIG domain ABC2_membrane PF01061.24 RLN88709.1 - 3.8e-10 39.5 19.4 3.8e-10 39.5 19.4 1.6 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN88709.1 - 1.3e-07 31.4 1.8 1.4e-07 31.3 0.0 2.1 2 1 1 3 3 3 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 RLN88709.1 - 0.00011 21.4 14.7 0.00013 21.2 14.7 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein PDR_assoc PF08370.11 RLN88709.1 - 0.012 15.3 0.1 0.012 15.3 0.1 2.9 3 1 1 4 4 4 0 Plant PDR ABC transporter associated YpmT PF17431.2 RLN88709.1 - 0.047 13.7 1.0 2.4 8.2 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized YmpT-like LETM1 PF07766.13 RLN88710.1 - 5.9e-52 176.7 0.1 7.5e-52 176.3 0.1 1.1 1 0 0 1 1 1 1 LETM1-like protein GAF_2 PF13185.6 RLN88711.1 - 1.3e-09 38.5 0.0 2.9e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 RLN88711.1 - 1.1e-07 32.6 0.7 3.1e-06 27.9 0.1 2.9 3 0 0 3 3 3 1 GAF domain FYVE PF01363.21 RLN88711.1 - 1.1e-05 25.5 18.2 2.9e-05 24.1 18.2 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN88711.1 - 0.033 14.4 9.6 0.098 12.9 9.6 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger AJAP1_PANP_C PF15298.6 RLN88713.1 - 2.3 8.4 11.0 4 7.6 11.0 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Mucin PF01456.17 RLN88713.1 - 2.8 7.9 28.5 0.34 10.9 20.4 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein TPR_17 PF13431.6 RLN88714.1 - 5.3e-15 54.6 11.1 0.002 18.4 0.3 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 RLN88714.1 - 3.1e-12 45.6 9.2 0.065 13.4 0.1 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 RLN88714.1 - 5.6e-11 42.8 7.9 0.00046 20.6 0.0 5.2 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN88714.1 - 1.4e-10 40.5 4.9 0.14 12.0 0.1 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 RLN88714.1 - 2e-10 40.0 5.5 0.066 13.5 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN88714.1 - 6.5e-08 32.1 5.5 0.0041 17.0 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN88714.1 - 3.4e-07 30.5 18.3 1 10.3 0.1 7.6 4 1 4 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 RLN88714.1 - 1.2e-05 25.5 17.6 0.17 12.2 0.1 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN88714.1 - 1.7e-05 24.4 2.7 2.1 8.1 0.1 4.6 5 0 0 5 5 4 2 TPR repeat TPR_9 PF13371.6 RLN88714.1 - 0.0044 17.1 8.6 0.033 14.3 0.7 4.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN88714.1 - 0.0053 17.4 11.5 1.2 9.8 1.2 4.8 3 1 0 4 4 4 1 Tetratricopeptide repeat SAP PF02037.27 RLN88714.1 - 0.023 14.5 4.4 4.8 7.0 0.4 3.5 2 2 0 2 2 2 0 SAP domain DUF4558 PF15104.6 RLN88714.1 - 0.025 14.6 3.5 3.5 7.8 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4558) ANAPC3 PF12895.7 RLN88714.1 - 4.1 7.7 6.3 19 5.6 0.0 3.2 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 adh_short PF00106.25 RLN88715.1 - 1.5e-18 67.0 0.0 2.2e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN88715.1 - 3.7e-12 46.3 0.1 5.3e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 RLN88715.1 - 0.16 11.3 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) MULE PF10551.9 RLN88716.1 - 1.3e-06 28.7 0.0 3e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 RLN88716.1 - 0.00016 21.3 0.1 0.00039 20.0 0.1 1.7 1 0 0 1 1 1 1 SWIM zinc finger DBD_Tnp_Mut PF03108.15 RLN88716.1 - 0.0021 18.0 0.1 0.0053 16.7 0.1 1.6 1 0 0 1 1 1 1 MuDR family transposase zf-CCHC_4 PF14392.6 RLN88716.1 - 0.18 11.6 0.4 0.42 10.4 0.4 1.7 1 0 0 1 1 1 0 Zinc knuckle AT_hook PF02178.19 RLN88716.1 - 0.42 10.6 4.6 0.13 12.2 0.5 2.3 2 0 0 2 2 2 0 AT hook motif zf-CCHC_2 PF13696.6 RLN88716.1 - 0.55 10.1 1.9 1 9.2 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Pro_dh PF01619.18 RLN88717.1 - 1.3e-78 264.5 0.0 4.6e-78 262.7 0.0 1.7 1 1 0 1 1 1 1 Proline dehydrogenase EF-hand_7 PF13499.6 RLN88717.1 - 0.009 16.5 0.0 0.022 15.2 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair Chorismate_synt PF01264.21 RLN88718.1 - 4.2e-50 170.3 0.0 4.7e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase HGTP_anticodon PF03129.20 RLN88719.1 - 3.9e-20 71.8 0.0 9.8e-20 70.5 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 RLN88719.1 - 5.8e-11 42.7 0.0 1.5e-09 38.1 0.0 2.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 RLN88719.1 - 1.3e-07 31.7 2.8 1.3e-07 31.7 2.8 2.3 2 0 0 2 2 2 1 WHEP-TRS domain Bac_rhamnosid_C PF17390.2 RLN88720.1 - 2.9e-11 43.0 0.2 1.1e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 RLN88720.1 - 4.2e-10 39.4 0.2 9.7e-10 38.2 0.2 1.7 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 RLN88720.1 - 0.022 13.6 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Trehalase MIP PF00230.20 RLN88721.1 - 0.0018 18.0 0.9 0.0023 17.7 0.9 1.2 1 0 0 1 1 1 1 Major intrinsic protein Ferric_reduct PF01794.19 RLN88722.1 - 4.1e-15 56.0 5.7 4.1e-15 56.0 5.7 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 RLN88722.1 - 9.5e-10 38.5 0.0 1.8e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.24 RLN88722.1 - 0.00037 20.8 0.1 0.0008 19.7 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain CrgA PF06781.12 RLN88722.1 - 0.065 13.3 3.4 4.7 7.3 0.1 2.8 2 0 0 2 2 2 0 Cell division protein CrgA PX PF00787.24 RLN88723.1 - 1.2e-06 28.5 0.1 2.2e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 PX domain CENP-H PF05837.12 RLN88723.1 - 0.019 15.4 8.6 0.032 14.6 8.6 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF3450 PF11932.8 RLN88723.1 - 0.12 11.6 9.1 0.19 11.0 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 RLN88723.1 - 0.49 10.6 3.9 1.2 9.4 3.9 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family COG2 PF06148.11 RLN88723.1 - 0.51 10.4 7.6 0.6 10.2 3.1 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 YabA PF06156.13 RLN88723.1 - 0.68 10.6 3.4 2.1 9.1 3.4 1.9 1 1 0 1 1 1 0 Initiation control protein YabA DUF737 PF05300.11 RLN88723.1 - 1.7 8.9 9.1 2.8 8.2 9.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Zwint PF15556.6 RLN88723.1 - 2.1 7.7 13.1 3.6 7.0 0.1 2.2 1 1 1 2 2 2 0 ZW10 interactor Myosin_head PF00063.21 RLN88724.1 - 1.9e-231 770.0 0.0 2.3e-231 769.7 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 RLN88724.1 - 0.017 14.9 0.2 0.036 13.9 0.2 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 RLN88724.1 - 0.022 15.1 0.2 0.088 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 RLN88724.1 - 0.027 14.6 1.0 0.055 13.5 0.2 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 RLN88724.1 - 0.049 13.9 0.0 0.21 11.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RLN88724.1 - 0.12 13.0 0.0 0.52 10.9 0.0 2.2 1 0 0 1 1 1 0 AAA domain Dynein_C PF18199.1 RLN88726.1 - 8.8e-99 330.6 0.0 1.5e-98 329.8 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 RLN88726.1 - 1.4e-90 302.2 0.3 1.5e-89 298.9 0.8 2.1 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 RLN88726.1 - 1.7e-56 190.5 0.0 3.1e-56 189.7 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RLN88726.1 - 4.2e-44 149.4 0.0 2.5e-40 137.2 0.0 2.6 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain Trans_reg_C PF00486.28 RLN88726.1 - 0.01 15.9 0.1 3.3 7.9 0.1 2.8 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal MT PF12777.7 RLN88726.1 - 0.056 12.5 0.0 0.13 11.2 0.0 1.6 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor Sun2_CC2 PF18580.1 RLN88726.1 - 0.12 12.6 0.3 0.32 11.3 0.3 1.7 1 0 0 1 1 1 0 SUN2 coiled coil domain 2 Pkinase PF00069.25 RLN88728.1 - 4.1e-56 190.3 0.0 5.7e-56 189.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN88728.1 - 5.4e-31 107.8 0.0 8.1e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN88728.1 - 0.00074 19.5 0.1 0.0032 17.4 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RLN88728.1 - 0.00089 18.7 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN88728.1 - 0.0022 17.4 0.0 0.0053 16.1 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RLN88728.1 - 0.022 13.7 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FYVE PF01363.21 RLN88728.1 - 0.076 13.2 15.7 0.1 12.8 13.2 2.2 2 0 0 2 2 2 0 FYVE zinc finger FYVE_2 PF02318.16 RLN88728.1 - 0.84 9.9 9.9 2.5 8.3 9.9 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger Ank_2 PF12796.7 RLN88729.1 - 2.5e-41 140.1 4.1 3.3e-13 50.0 0.0 5.1 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN88729.1 - 2.1e-31 107.8 4.9 7.2e-10 39.2 0.6 5.0 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN88729.1 - 1.5e-29 101.7 7.5 2.3e-07 30.9 0.2 7.1 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN88729.1 - 1.6e-26 89.4 3.6 0.0035 17.7 0.0 8.9 9 0 0 9 9 9 5 Ankyrin repeat Ank PF00023.30 RLN88729.1 - 2.2e-24 84.8 13.8 0.00016 21.9 0.1 8.7 8 1 0 8 8 8 4 Ankyrin repeat Pkinase_Tyr PF07714.17 RLN88729.1 - 3e-14 52.9 0.0 8e-14 51.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RLN88729.1 - 1.6e-09 37.6 0.0 2.6e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SRA1 PF07304.11 RLN88729.1 - 0.0036 17.1 0.1 0.0084 15.9 0.1 1.5 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) PrpR_N PF06506.11 RLN88729.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Propionate catabolism activator Tub PF01167.18 RLN88731.1 - 3.2e-43 148.2 0.1 2.5e-42 145.3 0.1 2.1 1 1 0 1 1 1 1 Tub family Hid1 PF12722.7 RLN88731.1 - 6.9 4.7 7.8 9 4.3 7.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4807 PF16065.5 RLN88732.1 - 4.6e-11 42.5 0.2 1.1e-10 41.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4807) Cyclin_N PF00134.23 RLN88733.1 - 1.6e-11 44.1 0.5 4.3e-11 42.6 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 RLN88733.1 - 0.014 15.5 0.1 6.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain DUF3427 PF11907.8 RLN88733.1 - 0.044 13.0 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3427) TFIIB PF00382.19 RLN88733.1 - 0.099 12.7 0.9 0.59 10.2 0.1 2.4 2 1 0 2 2 2 0 Transcription factor TFIIB repeat Glyco_hydro_3_C PF01915.22 RLN88735.1 - 4.5e-51 173.7 0.0 6.4e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RLN88735.1 - 6e-09 35.9 0.2 1.3e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 Fibronectin type III-like domain NOG1_N PF17835.1 RLN88736.1 - 1.6e-55 187.4 1.4 1.6e-55 187.4 1.4 2.7 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 RLN88736.1 - 6.4e-27 93.1 0.9 1.2e-26 92.2 0.2 2.0 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 RLN88736.1 - 6.2e-24 83.7 1.2 1.4e-23 82.6 1.2 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 RLN88736.1 - 1.8e-17 63.4 0.0 5e-17 62.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN88736.1 - 2.8e-10 39.9 0.1 4.8e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 RLN88736.1 - 0.00017 21.2 0.2 0.00039 20.1 0.2 1.6 1 0 0 1 1 1 1 Ras family Dynamin_N PF00350.23 RLN88736.1 - 0.02 14.9 2.3 5.7 7.0 0.0 3.4 2 1 1 3 3 3 0 Dynamin family AAA_16 PF13191.6 RLN88736.1 - 0.12 12.7 2.9 0.15 12.5 0.0 2.7 2 2 0 2 2 2 0 AAA ATPase domain PWWP PF00855.17 RLN88737.1 - 2.6e-08 34.2 1.2 7.7e-08 32.7 1.2 1.8 1 0 0 1 1 1 1 PWWP domain Nop14 PF04147.12 RLN88737.1 - 0.18 10.0 5.9 0.26 9.4 5.9 1.2 1 0 0 1 1 1 0 Nop14-like family RNA_polI_A34 PF08208.11 RLN88737.1 - 1.2 9.1 10.3 2.7 8.1 10.3 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 NOA36 PF06524.12 RLN88737.1 - 4.8 6.4 8.6 10 5.4 8.6 1.4 1 0 0 1 1 1 0 NOA36 protein BT1 PF03092.16 RLN88738.1 - 1.6e-20 72.9 14.1 5.5e-14 51.3 1.2 3.3 3 0 0 3 3 3 3 BT1 family DUF5083 PF16890.5 RLN88738.1 - 0.05 13.3 2.1 0.57 9.9 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5083) DUF3810 PF12725.7 RLN88738.1 - 2.5 7.4 7.8 4.7 6.5 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Flavodoxin_2 PF02525.17 RLN88739.1 - 2.2e-30 105.8 0.4 4.1e-29 101.7 0.4 2.0 1 1 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 RLN88739.1 - 2.7e-11 43.5 0.0 6e-11 42.3 0.0 1.5 1 1 0 1 1 1 1 NADPH-dependent FMN reductase PriCT_2 PF08707.11 RLN88739.1 - 0.11 12.9 0.1 0.23 11.9 0.1 1.5 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) DNA_pol_A_exo1 PF01612.20 RLN88740.1 - 5.3e-17 62.1 0.2 3.3e-14 53.0 0.2 2.3 1 1 0 1 1 1 1 3'-5' exonuclease zf-C2H2_4 PF13894.6 RLN88740.1 - 0.32 11.9 8.2 0.29 12.1 0.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 RLN88740.1 - 0.58 10.5 6.5 1.3 9.4 6.5 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding RR_TM4-6 PF06459.12 RLN88740.1 - 9.5 6.0 13.3 16 5.3 13.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mannosyl_trans PF05007.13 RLN88742.1 - 3.2e-47 161.6 25.6 4.2e-28 98.9 4.9 3.2 1 1 2 3 3 3 3 Mannosyltransferase (PIG-M) PIG-U PF06728.13 RLN88742.1 - 2.8e-05 23.4 16.2 0.019 14.0 0.1 2.6 1 1 1 2 2 2 2 GPI transamidase subunit PIG-U GT87 PF09594.10 RLN88742.1 - 0.0026 17.5 5.5 0.0026 17.5 5.5 3.5 2 2 1 3 3 3 2 Glycosyltransferase family 87 HMA PF00403.26 RLN88743.1 - 5.3e-06 26.8 0.4 7.2e-06 26.4 0.4 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain Exo_endo_phos PF03372.23 RLN88744.1 - 7.6e-10 38.7 0.1 2.9e-09 36.8 0.1 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 RLN88744.1 - 0.00011 22.0 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Glyco_hydro_3 PF00933.21 RLN88745.1 - 6.1e-52 177.0 0.0 8.3e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN88745.1 - 5.8e-06 26.4 0.0 2.7e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 RLN88746.1 - 6.1e-52 177.0 0.0 8.3e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN88746.1 - 5.8e-06 26.4 0.0 2.7e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain RVT_1 PF00078.27 RLN88747.1 - 5.1e-35 121.0 0.1 2.7e-34 118.6 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_S66 PF02016.15 RLN88747.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain Pkinase PF00069.25 RLN88748.1 - 7.7e-69 232.0 0.0 1.1e-68 231.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.18 RLN88748.1 - 6.7e-38 128.7 0.1 2.2e-19 69.4 0.1 2.5 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.17 RLN88748.1 - 2.8e-36 125.1 0.0 4.2e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN88748.1 - 6.3e-07 29.0 0.0 1.9e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 RLN88748.1 - 0.012 15.6 0.1 0.029 14.3 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.7 RLN88749.1 - 3.4e-40 136.5 28.5 2.4e-07 31.3 0.1 6.1 2 2 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN88749.1 - 7.9e-33 112.4 19.1 9.9e-07 29.2 0.2 8.5 6 2 3 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN88749.1 - 2.4e-30 104.2 27.3 0.0021 18.3 0.0 13.0 3 2 11 14 14 14 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN88749.1 - 6.8e-19 66.0 11.5 1.1 10.0 0.0 12.6 11 2 2 13 13 12 3 Ankyrin repeat HA PF03457.14 RLN88749.1 - 1.5e-06 28.4 0.0 0.9 9.9 0.0 5.8 3 2 2 5 5 5 2 Helicase associated domain Ank PF00023.30 RLN88749.1 - 1.9e-05 24.9 9.3 30 5.3 0.0 9.2 2 2 4 6 6 6 0 Ankyrin repeat DUF4411 PF14367.6 RLN88749.1 - 0.0003 20.7 2.0 17 5.3 0.0 4.3 2 2 3 5 5 5 0 Domain of unknown function (DUF4411) JAB PF01398.21 RLN88749.1 - 0.053 13.5 2.5 11 6.0 0.1 4.3 3 2 1 4 4 4 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF1987 PF09345.10 RLN88749.1 - 0.17 11.5 3.1 1.1e+02 2.5 0.0 5.0 3 2 1 5 5 5 0 Domain of unknown function (DUF1987) UPF0489 PF12640.7 RLN88749.1 - 0.3 11.3 3.5 14 5.8 0.1 4.2 2 2 2 4 4 4 0 UPF0489 domain DUF1843 PF08898.10 RLN88749.1 - 1 9.9 3.9 16 6.1 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) TPR_19 PF14559.6 RLN88750.1 - 1.2e-51 173.1 59.6 3.5e-07 30.6 0.9 16.7 13 4 3 17 17 16 13 Tetratricopeptide repeat TPR_2 PF07719.17 RLN88750.1 - 1.5e-34 115.3 63.4 0.0061 16.6 0.0 23.2 26 0 0 26 26 24 8 Tetratricopeptide repeat TPR_14 PF13428.6 RLN88750.1 - 2.3e-31 105.8 66.0 0.0024 18.6 0.0 21.1 15 6 8 23 23 21 8 Tetratricopeptide repeat TPR_16 PF13432.6 RLN88750.1 - 6.9e-30 103.4 56.1 0.0063 17.1 0.0 16.1 14 2 2 16 16 16 9 Tetratricopeptide repeat TPR_8 PF13181.6 RLN88750.1 - 1.6e-25 87.1 31.1 0.0081 16.3 0.1 17.2 19 0 0 19 19 15 5 Tetratricopeptide repeat TPR_1 PF00515.28 RLN88750.1 - 3.8e-24 83.5 50.5 0.0022 17.7 0.1 19.2 22 0 0 22 22 20 4 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN88750.1 - 2.5e-19 69.3 42.1 0.0052 17.0 0.1 11.1 8 5 3 11 11 10 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 RLN88750.1 - 4.8e-17 62.0 59.0 0.013 15.7 0.3 16.0 11 5 3 14 14 14 6 Tetratricopeptide repeat TPR_11 PF13414.6 RLN88750.1 - 1.5e-10 40.6 27.3 0.00021 20.9 0.1 11.4 14 1 1 15 15 12 3 TPR repeat TPR_7 PF13176.6 RLN88750.1 - 3.9e-10 39.0 49.2 0.018 15.1 0.0 16.9 18 1 1 19 19 19 3 Tetratricopeptide repeat TPR_9 PF13371.6 RLN88750.1 - 1.7e-08 34.5 45.8 5.1e-05 23.3 0.2 9.3 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 RLN88750.1 - 2.2e-08 34.2 60.1 0.44 11.3 0.2 19.1 23 0 0 23 23 18 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN88750.1 - 1.5e-06 28.2 29.9 3.1 8.4 0.3 13.5 17 0 0 17 17 11 1 Tetratricopeptide repeat RPN7 PF10602.9 RLN88750.1 - 0.00083 19.1 4.5 3.3 7.4 0.1 6.0 6 1 0 7 7 6 1 26S proteasome subunit RPN7 ChAPs PF09295.10 RLN88750.1 - 0.0017 17.5 8.0 0.035 13.1 0.1 4.7 3 1 0 5 5 5 1 ChAPs (Chs5p-Arf1p-binding proteins) LppC PF04348.13 RLN88750.1 - 0.0027 16.6 0.3 0.0027 16.6 0.3 3.5 4 1 1 5 5 5 2 LppC putative lipoprotein YfiO PF13525.6 RLN88750.1 - 0.003 17.3 1.8 3.2 7.4 0.0 4.9 5 0 0 5 5 4 1 Outer membrane lipoprotein Coatomer_E PF04733.14 RLN88750.1 - 0.0034 16.8 12.5 0.23 10.8 0.0 5.4 7 0 0 7 7 7 2 Coatomer epsilon subunit Alkyl_sulf_dimr PF14863.6 RLN88750.1 - 0.014 15.8 14.4 17 5.9 0.3 7.4 8 1 1 9 9 6 0 Alkyl sulfatase dimerisation TPR_21 PF09976.9 RLN88750.1 - 0.019 14.7 33.7 0.36 10.5 0.8 7.6 7 1 1 8 8 8 0 Tetratricopeptide repeat-like domain DUF627 PF04781.12 RLN88750.1 - 0.02 14.9 3.3 9.4 6.3 0.1 4.4 4 1 0 4 4 2 0 Protein of unknown function (DUF627) TPR_4 PF07721.14 RLN88750.1 - 0.028 15.0 51.2 2 9.3 2.3 13.2 14 0 0 14 14 11 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN88750.1 - 0.07 13.0 27.8 7.1 6.7 0.1 10.6 12 0 0 12 12 11 0 Tetratricopeptide repeat PknG_TPR PF16918.5 RLN88750.1 - 0.078 11.7 0.1 0.078 11.7 0.1 5.9 7 1 0 8 8 8 0 Protein kinase G tetratricopeptide repeat SHNi-TPR PF10516.9 RLN88750.1 - 0.081 12.4 2.2 6.8 6.2 0.1 4.1 3 0 0 3 3 3 0 SHNi-TPR MIT PF04212.18 RLN88750.1 - 0.086 12.9 10.2 30 4.8 0.1 6.9 8 0 0 8 8 5 0 MIT (microtubule interacting and transport) domain PPR PF01535.20 RLN88750.1 - 0.087 13.1 6.0 66 4.1 0.0 6.9 9 0 0 9 9 4 0 PPR repeat DUF5071 PF16804.5 RLN88750.1 - 0.089 13.0 0.0 28 5.0 0.0 3.0 3 0 0 3 3 2 0 Domain of unknown function (DUF5071) Fis1_TPR_C PF14853.6 RLN88750.1 - 0.16 12.0 18.6 9.9 6.3 0.1 8.3 10 1 0 10 10 8 0 Fis1 C-terminal tetratricopeptide repeat ImpA_N PF06812.12 RLN88750.1 - 1.5 9.0 4.4 5.3 7.2 0.0 4.0 4 0 0 4 4 3 0 ImpA, N-terminal, type VI secretion system zf-C2HC_2 PF13913.6 RLN88751.1 - 7.9e-14 51.1 17.8 3.6e-09 36.3 0.4 3.4 3 0 0 3 3 3 2 zinc-finger of a C2HC-type WW PF00397.26 RLN88751.1 - 1.5e-09 37.8 3.8 3e-09 36.8 3.8 1.5 1 0 0 1 1 1 1 WW domain Sgf11 PF08209.11 RLN88751.1 - 4.7 6.9 15.5 0.53 9.9 0.9 3.1 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) ABC_membrane PF00664.23 RLN88752.1 - 9.8e-33 114.0 2.2 1.3e-32 113.6 2.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN88752.1 - 1.1e-28 100.5 0.0 1.9e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN88752.1 - 3.7e-05 23.3 0.0 0.0056 16.1 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RLN88752.1 - 0.0038 17.3 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 RLN88752.1 - 0.007 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.17 RLN88752.1 - 0.0071 16.5 0.1 0.017 15.2 0.1 1.6 2 0 0 2 2 2 1 Helicase HerA, central domain DEAD PF00270.29 RLN88752.1 - 0.029 14.1 0.0 0.14 11.9 0.0 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_21 PF13304.6 RLN88752.1 - 0.13 12.1 0.2 0.86 9.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RLN88752.1 - 0.26 11.8 0.0 0.46 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF981 PF06168.11 RLN88752.1 - 0.4 10.6 4.9 0.1 12.5 1.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF981) DUF778 PF05608.12 RLN88753.1 - 4.8e-19 69.5 0.1 7.1e-19 68.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF778) Kelch_4 PF13418.6 RLN88754.1 - 3.9e-32 110.0 27.7 1.4e-09 37.8 0.1 9.3 8 1 0 8 8 8 6 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN88754.1 - 2.6e-25 87.9 27.0 6.2e-06 26.1 1.0 8.4 8 1 0 8 8 8 5 Kelch motif TPR_2 PF07719.17 RLN88754.1 - 2.3e-24 83.5 23.4 0.024 14.7 0.0 11.5 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_1 PF00515.28 RLN88754.1 - 4e-20 70.7 36.7 0.004 16.9 0.0 11.6 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_6 PF13174.6 RLN88754.1 - 7e-20 70.3 3.5 0.0067 17.0 0.1 11.1 11 0 0 11 11 11 3 Tetratricopeptide repeat Kelch_3 PF13415.6 RLN88754.1 - 6.5e-19 67.8 20.2 0.0048 17.2 1.8 9.2 8 1 0 8 8 8 5 Galactose oxidase, central domain TPR_19 PF14559.6 RLN88754.1 - 1.8e-18 66.8 14.9 0.0013 19.2 0.0 7.9 5 3 0 7 7 7 3 Tetratricopeptide repeat Kelch_1 PF01344.25 RLN88754.1 - 1.6e-17 62.8 19.2 0.00085 18.9 0.6 7.7 7 2 0 7 7 7 5 Kelch motif TPR_12 PF13424.6 RLN88754.1 - 1e-16 61.0 20.1 0.0008 19.7 0.0 9.1 7 3 1 9 9 9 4 Tetratricopeptide repeat Kelch_2 PF07646.15 RLN88754.1 - 3.4e-16 58.5 13.7 0.00078 19.3 0.4 7.4 6 2 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 RLN88754.1 - 2.6e-15 56.1 20.6 0.00085 19.5 0.3 9.3 8 1 0 8 8 8 2 Kelch motif TPR_14 PF13428.6 RLN88754.1 - 1.2e-14 53.7 2.3 0.16 12.9 0.0 8.4 7 3 3 10 10 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN88754.1 - 5.3e-14 51.1 15.8 0.05 13.7 0.0 8.9 10 0 0 10 10 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN88754.1 - 9.7e-13 48.2 21.0 0.00099 19.3 1.0 7.0 6 1 1 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 RLN88754.1 - 4.3e-10 39.1 11.3 0.24 11.1 0.0 7.8 7 1 1 8 8 8 3 TPR repeat EGF_2 PF07974.13 RLN88754.1 - 9.1e-10 38.7 45.4 0.00016 22.0 12.0 3.9 3 0 0 3 3 3 3 EGF-like domain TPR_8 PF13181.6 RLN88754.1 - 2.7e-09 36.5 25.1 0.22 11.8 0.0 10.5 12 0 0 12 12 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 RLN88754.1 - 4.9e-08 33.5 9.8 0.65 10.7 0.0 7.6 4 4 5 10 10 10 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN88754.1 - 8.1e-08 32.3 0.0 0.12 12.5 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 RLN88754.1 - 2.1e-05 24.6 5.7 0.28 11.7 0.0 5.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 RLN88754.1 - 0.00017 21.1 9.5 0.4 10.0 0.0 5.5 5 1 1 6 6 6 2 MalT-like TPR region TPR_21 PF09976.9 RLN88754.1 - 0.00019 21.2 4.1 0.0037 17.0 0.5 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat-like domain DUF3808 PF10300.9 RLN88754.1 - 0.002 17.0 1.7 0.036 12.8 0.0 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF3808) Fis1_TPR_C PF14853.6 RLN88754.1 - 0.0058 16.7 2.0 5 7.3 0.0 5.3 5 1 1 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat DUF2225 PF09986.9 RLN88754.1 - 0.0074 16.0 0.5 0.0074 16.0 0.5 4.2 3 1 0 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) DUF4810 PF16068.5 RLN88754.1 - 0.026 15.1 0.8 7 7.3 0.0 4.8 6 0 0 6 6 5 0 Domain of unknown function (DUF4810) Glyco_tran_28_C PF04101.16 RLN88754.1 - 0.15 12.0 0.1 0.44 10.5 0.1 1.7 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain TPR_20 PF14561.6 RLN88754.1 - 0.54 10.6 8.6 11 6.4 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 RLN88754.1 - 0.92 9.5 12.4 3.7 7.6 0.6 4.6 3 2 2 5 5 5 0 Putative TPR-like repeat hEGF PF12661.7 RLN88754.1 - 2.5 8.8 27.6 5 7.9 5.3 4.2 3 0 0 3 3 3 0 Human growth factor-like EGF RRM_1 PF00076.22 RLN88758.1 - 4.4e-17 61.7 0.1 8.2e-17 60.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN88758.1 - 0.0073 16.4 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif PNISR PF15996.5 RLN88758.1 - 2.9 8.1 18.0 0.55 10.5 12.3 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR API5 PF05918.11 RLN88758.1 - 5.9 5.6 10.0 12 4.5 10.0 1.6 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) NARP1 PF12569.8 RLN88758.1 - 6.8 5.5 9.5 11 4.8 9.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Beach PF02138.18 RLN88761.1 - 2.4e-113 378.1 0.0 5e-113 377.1 0.0 1.6 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 RLN88761.1 - 2.1e-15 56.7 0.0 4.4e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 RLN88761.1 - 4e-05 23.8 0.0 9.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily zf-C3HC4_3 PF13920.6 RLN88761.1 - 0.023 14.5 10.7 0.056 13.3 10.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4704 PF15787.5 RLN88761.1 - 0.059 12.6 1.6 0.16 11.2 1.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) zf-C3HC4 PF00097.25 RLN88761.1 - 0.17 11.8 9.7 0.48 10.4 9.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN88761.1 - 1.7 9.0 12.1 2.4 8.6 10.1 2.4 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 RLN88761.1 - 3.6 7.6 10.7 8.6 6.4 10.7 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Guanylate_cyc PF00211.20 RLN88762.1 - 8.6e-95 315.6 0.5 2.9e-47 160.7 0.1 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 RLN88762.1 - 0.05 13.0 0.5 0.68 9.3 0.1 2.2 2 0 0 2 2 2 0 Heme NO binding associated DUF4271 PF14093.6 RLN88762.1 - 0.053 13.4 0.1 0.053 13.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) DUF5391 PF17369.2 RLN88762.1 - 2.3 8.2 7.7 0.12 12.4 0.9 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5391) PALP PF00291.25 RLN88763.1 - 7e-74 248.9 4.2 7e-74 248.9 4.2 1.4 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 RLN88763.1 - 2.2e-32 110.7 0.1 2.9e-23 81.5 0.0 2.7 2 1 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase TPR_1 PF00515.28 RLN88764.1 - 1.7e-12 46.6 6.8 0.0029 17.3 0.0 6.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN88764.1 - 3.1e-11 42.5 12.8 0.014 15.5 0.0 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN88764.1 - 3.2e-11 42.5 5.6 0.0027 17.8 0.0 5.5 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 RLN88764.1 - 2.2e-10 40.6 7.9 0.055 13.8 0.6 5.0 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN88764.1 - 2.3e-08 33.5 11.3 0.71 10.0 0.0 6.7 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN88764.1 - 2.5e-06 27.9 17.6 0.0013 19.2 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN88764.1 - 6e-05 23.5 10.0 1.1 10.3 0.1 5.2 3 3 3 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN88764.1 - 0.00027 21.1 0.9 4.8 7.8 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN88764.1 - 0.00036 20.6 4.3 0.61 10.3 0.0 3.6 3 1 0 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 RLN88764.1 - 0.00056 20.4 2.6 0.61 10.8 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN88764.1 - 0.00067 19.3 0.2 22 4.8 0.0 4.7 3 1 1 4 4 4 0 TPR repeat TPR_15 PF13429.6 RLN88764.1 - 0.0008 18.7 7.0 0.53 9.4 0.4 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN88764.1 - 0.00085 19.9 5.0 4.7 7.9 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.17 RLN88764.1 - 0.001 19.5 2.5 0.0029 18.0 0.1 2.8 2 2 1 3 3 3 1 Bacterial transcriptional activator domain ANAPC3 PF12895.7 RLN88764.1 - 0.0013 18.9 6.3 0.082 13.1 0.1 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 RLN88764.1 - 0.0014 17.7 2.3 0.11 11.4 0.1 2.1 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) CENP-H PF05837.12 RLN88764.1 - 0.0043 17.4 2.3 7.4 7.0 0.0 3.2 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Bcr-Abl_Oligo PF09036.10 RLN88764.1 - 0.023 14.7 0.6 2.9 7.9 0.4 2.7 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain NARP1 PF12569.8 RLN88764.1 - 0.023 13.6 4.6 0.039 12.9 0.9 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 BORCS8 PF10167.9 RLN88764.1 - 0.035 14.0 0.1 5.1 7.1 0.0 2.5 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 YbfN PF13982.6 RLN88764.1 - 0.037 14.3 0.1 0.39 11.0 0.0 2.4 2 0 0 2 2 2 0 YbfN-like lipoprotein DUF5339 PF17274.2 RLN88764.1 - 0.095 13.6 2.9 12 6.9 0.2 3.3 3 0 0 3 3 2 0 Family of unknown function (DUF5339) PspA_IM30 PF04012.12 RLN88764.1 - 0.27 10.8 5.2 0.77 9.3 1.6 2.5 2 0 0 2 2 2 0 PspA/IM30 family FbpA PF05833.11 RLN88764.1 - 0.27 9.9 2.6 0.57 8.9 1.1 2.0 1 1 1 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) MIT PF04212.18 RLN88764.1 - 0.88 9.7 7.3 6.1 7.0 0.0 4.3 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 RLN88764.1 - 2.9 7.9 8.6 22 5.1 0.2 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat DnaT PF17948.1 RLN88765.1 - 0.016 14.8 0.3 0.036 13.7 0.1 1.6 2 0 0 2 2 2 0 DnaT DNA-binding domain MORN PF02493.20 RLN88767.1 - 2.1e-70 228.6 121.4 1.3e-08 34.3 3.3 17.7 18 0 0 18 18 18 16 MORN repeat DUF3211 PF11485.8 RLN88767.1 - 0.21 11.8 0.4 0.61 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3211) PMR5N PF14416.6 RLN88767.1 - 1.1 9.6 4.5 3.8 7.9 0.0 4.0 4 0 0 4 4 4 0 PMR5 N terminal Domain FH2 PF02181.23 RLN88768.1 - 5.3e-45 154.1 3.1 9.2e-45 153.4 3.1 1.4 1 0 0 1 1 1 1 Formin Homology 2 Domain PAN_1 PF00024.26 RLN88768.1 - 6.2e-05 22.9 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 PAN domain FliD_C PF07195.12 RLN88768.1 - 0.0025 17.3 0.1 0.0055 16.2 0.1 1.6 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus PAN_4 PF14295.6 RLN88768.1 - 0.0036 17.2 0.2 0.0081 16.0 0.2 1.5 1 0 0 1 1 1 1 PAN domain Mrx7 PF10906.8 RLN88768.1 - 0.14 12.4 0.0 0.49 10.7 0.0 1.9 1 0 0 1 1 1 0 MIOREX complex component 7 C2 PF00168.30 RLN88769.1 - 1.2e-11 44.8 0.1 8.1e-10 38.9 0.1 3.0 1 1 0 1 1 1 1 C2 domain DUF3775 PF12616.8 RLN88769.1 - 0.12 12.4 0.4 0.6 10.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3775) Ins134_P3_kin PF05770.11 RLN88770.1 - 2.7e-23 82.5 0.1 1.7e-20 73.4 0.1 2.3 2 0 0 2 2 2 2 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 RLN88770.1 - 0.017 15.5 0.0 0.053 13.9 0.0 1.8 2 0 0 2 2 2 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain ATP-grasp_3 PF02655.14 RLN88770.1 - 0.093 12.8 0.0 0.17 11.9 0.0 1.5 1 1 0 1 1 1 0 ATP-grasp domain Ribonuc_red_lgC PF02867.15 RLN88771.1 - 1.3e-155 519.0 0.0 1.6e-155 518.6 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 RLN88771.1 - 1e-24 86.4 0.1 1.9e-22 79.1 0.0 2.5 2 0 0 2 2 2 2 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 RLN88771.1 - 3.2e-18 66.1 0.0 7.1e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 ATP cone domain FKBP_C PF00254.28 RLN88772.1 - 8e-50 167.1 0.0 5e-32 110.1 0.0 2.4 2 1 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TP_methylase PF00590.20 RLN88773.1 - 5.5e-05 23.2 0.0 6.8e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Pkinase_Tyr PF07714.17 RLN88775.1 - 1.5e-27 96.6 0.0 3e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN88775.1 - 5.2e-19 68.6 0.0 1.2e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain ADH_N PF08240.12 RLN88776.1 - 5.7e-26 90.5 2.8 1.1e-25 89.6 2.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN88776.1 - 4.1e-17 62.4 0.7 6.8e-17 61.7 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN88776.1 - 1.9e-05 25.7 0.0 3.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN88776.1 - 0.00033 20.1 0.6 0.0015 17.9 0.2 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN88776.1 - 0.045 13.1 0.6 0.075 12.3 0.6 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain KR PF08659.10 RLN88776.1 - 0.069 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 KR domain Glyco_hydro_6 PF01341.17 RLN88777.1 - 1.8e-48 165.8 1.0 3.1e-48 165.1 1.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Glyco_hydro_6 PF01341.17 RLN88778.1 - 8.6e-49 166.9 1.4 1.1e-48 166.5 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Glyco_hydro_6 PF01341.17 RLN88779.1 - 9.9e-11 41.9 0.2 1.6e-10 41.3 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Med3 PF11593.8 RLN88779.1 - 0.36 10.0 10.4 0.52 9.4 10.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Hamartin PF04388.12 RLN88779.1 - 2 7.0 8.5 2.1 6.9 8.5 1.0 1 0 0 1 1 1 0 Hamartin protein SOG2 PF10428.9 RLN88779.1 - 2.6 7.1 14.5 2.6 7.1 14.5 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein ATF7IP_BD PF16788.5 RLN88779.1 - 6.4 6.8 9.0 8.5 6.4 9.0 1.1 1 0 0 1 1 1 0 ATF-interacting protein binding domain Pkinase PF00069.25 RLN88780.1 - 1.3e-18 67.3 0.0 1.8e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PX PF00787.24 RLN88780.1 - 3.3e-12 46.4 0.5 8.2e-12 45.1 0.5 1.6 1 0 0 1 1 1 1 PX domain Pkinase_Tyr PF07714.17 RLN88780.1 - 4.2e-10 39.4 0.1 5.8e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DLH PF01738.18 RLN88780.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family HTH_psq PF05225.16 RLN88781.1 - 7.8e-15 54.3 0.3 1.7e-14 53.3 0.3 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Aminotran_1_2 PF00155.21 RLN88781.1 - 3.3e-14 52.9 0.0 2.9e-10 39.8 0.0 2.2 1 1 1 2 2 2 2 Aminotransferase class I and II HTH_Tnp_ISL3 PF13542.6 RLN88781.1 - 0.0016 17.8 0.0 0.0045 16.4 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 RLN88781.1 - 0.0034 17.5 0.3 0.0071 16.5 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 RLN88781.1 - 0.035 13.9 0.1 0.077 12.8 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_17 PF12728.7 RLN88781.1 - 0.054 13.7 0.0 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Kinesin PF00225.23 RLN88782.1 - 1.4e-53 182.0 6.7 1.2e-51 175.6 0.4 2.7 2 1 1 3 3 2 2 Kinesin motor domain AAA PF00004.29 RLN88782.1 - 3.6e-18 66.3 0.0 2.5e-16 60.3 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Microtub_bd PF16796.5 RLN88782.1 - 4.2e-11 43.0 0.0 1.3e-10 41.4 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 RLN88782.1 - 1.9e-09 38.1 0.0 0.0012 19.3 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 RLN88782.1 - 6.3e-06 26.5 0.0 0.1 12.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN88782.1 - 0.00036 19.9 0.0 0.91 8.8 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin TsaE PF02367.17 RLN88782.1 - 0.00041 20.3 0.0 0.6 10.1 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 RLN88782.1 - 0.00043 20.5 0.1 0.14 12.4 0.0 3.3 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.12 RLN88782.1 - 0.00092 19.0 0.0 0.0027 17.5 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 RLN88782.1 - 0.0019 18.0 3.1 1.5 8.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 RLN88782.1 - 0.0023 18.3 0.0 2.6 8.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 RLN88782.1 - 0.004 16.7 0.0 2.2 7.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 RLN88782.1 - 0.006 16.5 0.1 1.2 9.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 RLN88782.1 - 0.0064 17.0 0.5 2.9 8.4 0.0 3.9 4 0 0 4 4 3 1 AAA domain AAA_5 PF07728.14 RLN88782.1 - 0.0067 16.4 0.4 0.57 10.2 0.0 3.3 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 RLN88782.1 - 0.0073 16.0 0.4 1.8 8.2 0.0 3.3 3 1 0 3 3 3 1 Sigma-54 interaction domain AAA_28 PF13521.6 RLN88782.1 - 0.0073 16.6 0.0 0.27 11.4 0.0 3.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 RLN88782.1 - 0.02 14.9 0.0 8 6.4 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 RLN88782.1 - 0.026 14.3 0.2 10 5.8 0.0 3.5 3 1 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 RLN88782.1 - 0.054 13.2 0.0 4.1 7.1 0.0 2.6 3 0 0 3 3 2 0 IstB-like ATP binding protein Bac_DnaA PF00308.18 RLN88782.1 - 0.065 13.1 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial dnaA protein TIP49 PF06068.13 RLN88782.1 - 0.08 12.1 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 TIP49 P-loop domain PhoH PF02562.16 RLN88782.1 - 0.13 11.7 0.0 21 4.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein CDC45 PF02724.14 RLN88782.1 - 0.28 9.4 4.0 0.62 8.3 4.0 1.6 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RLN88782.1 - 0.36 9.0 18.3 0.01 14.1 11.8 1.6 2 0 0 2 2 2 0 Nop14-like family AAA_17 PF13207.6 RLN88782.1 - 0.4 11.1 2.4 12 6.3 0.0 3.6 4 0 0 4 4 3 0 AAA domain AAA_11 PF13086.6 RLN88782.1 - 0.56 10.0 0.0 0.56 10.0 0.0 3.5 5 0 0 5 5 5 0 AAA domain RRN3 PF05327.11 RLN88782.1 - 1.3 7.5 4.7 2.1 6.8 4.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-RING_2 PF13639.6 RLN88785.1 - 1.7e-10 41.1 12.9 3.1e-10 40.2 12.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN88785.1 - 8.8e-10 38.3 12.7 1.6e-09 37.4 12.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN88785.1 - 1.6e-06 28.3 8.6 4.8e-06 26.8 8.6 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 RLN88785.1 - 2.1e-06 27.5 10.3 3.8e-06 26.7 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN88785.1 - 6.7e-06 25.9 13.1 1.2e-05 25.0 13.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN88785.1 - 7.1e-06 25.9 6.5 7.1e-06 25.9 6.5 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN88785.1 - 1.1e-05 25.2 12.0 2.1e-05 24.4 12.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 RLN88785.1 - 5.4e-05 22.8 13.7 0.0001 21.9 11.4 2.3 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 RLN88785.1 - 0.00031 20.5 10.8 0.00061 19.6 10.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 RLN88785.1 - 0.007 16.1 7.0 0.018 14.8 7.0 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Rtf2 PF04641.12 RLN88785.1 - 0.012 15.0 2.1 0.08 12.3 2.1 2.2 1 1 1 2 2 2 0 Rtf2 RING-finger zf-ANAPC11 PF12861.7 RLN88785.1 - 0.013 15.5 3.2 0.031 14.3 3.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 RLN88785.1 - 0.017 14.7 9.1 0.031 13.9 9.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 RLN88785.1 - 0.031 14.2 10.1 0.37 10.8 5.1 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-Nse PF11789.8 RLN88785.1 - 0.097 12.5 5.4 0.19 11.6 5.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 RLN88785.1 - 0.14 12.0 3.9 0.36 10.7 3.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-TFIIIC PF12660.7 RLN88785.1 - 0.22 11.5 2.3 0.18 11.8 0.6 1.8 2 0 0 2 2 1 0 Putative zinc-finger of transcription factor IIIC complex DEDD_Tnp_IS110 PF01548.17 RLN88785.1 - 0.28 11.0 3.3 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 Transposase DUF4140 PF13600.6 RLN88785.1 - 0.32 11.5 2.2 0.36 11.3 0.3 2.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 RLN88785.1 - 0.81 10.2 10.9 0.23 12.0 6.8 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Zf_RING PF16744.5 RLN88785.1 - 3.4 7.8 7.5 11 6.2 7.4 1.8 1 1 0 1 1 1 0 KIAA1045 RING finger DivIC PF04977.15 RLN88785.1 - 4.1 7.2 7.4 1.1 9.1 3.9 1.9 2 0 0 2 2 1 0 Septum formation initiator zf-C3HC4_4 PF15227.6 RLN88785.1 - 4.1 7.6 8.3 11 6.3 8.3 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING PRIMA1 PF16101.5 RLN88786.1 - 0.099 12.7 0.2 0.19 11.8 0.2 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 RRM_1 PF00076.22 RLN88787.1 - 7.9e-11 41.6 0.0 1e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2457 PF10446.9 RLN88787.1 - 0.0047 16.1 8.4 0.0059 15.8 8.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Limkain-b1 PF11608.8 RLN88787.1 - 0.0061 16.6 0.0 0.0094 16.0 0.0 1.3 1 0 0 1 1 1 1 Limkain b1 RRM_3 PF08777.11 RLN88787.1 - 0.066 13.3 0.0 0.093 12.8 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif FimA PF16970.5 RLN88787.1 - 0.2 11.8 0.0 0.26 11.5 0.0 1.1 1 0 0 1 1 1 0 Type-1 fimbrial protein, A Ribosomal_L38e PF01781.18 RLN88788.1 - 1.5e-32 111.5 1.8 2e-32 111.1 1.8 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family PNRC PF15365.6 RLN88789.1 - 0.12 12.3 0.0 0.12 12.3 0.0 2.8 3 0 0 3 3 3 0 Proline-rich nuclear receptor coactivator motif RNase_PH PF01138.21 RLN88790.1 - 1.8e-32 112.6 0.0 2.1e-18 67.1 0.0 2.6 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RLN88790.1 - 1.7e-13 50.4 0.1 3.3e-08 33.5 0.0 2.7 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 KH_1 PF00013.29 RLN88790.1 - 1.9e-09 37.2 0.0 8.9e-09 35.1 0.0 2.1 2 0 0 2 2 2 1 KH domain S1 PF00575.23 RLN88790.1 - 1.9e-09 37.7 0.1 1.2e-08 35.2 0.0 2.2 2 0 0 2 2 2 1 S1 RNA binding domain KH_2 PF07650.17 RLN88790.1 - 0.036 13.9 0.1 0.095 12.5 0.1 1.7 1 0 0 1 1 1 0 KH domain KH_5 PF13184.6 RLN88790.1 - 0.068 13.3 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 NusA-like KH domain ANAPC3 PF12895.7 RLN88791.1 - 0.0054 16.9 0.4 0.89 9.8 0.0 3.6 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF1759 PF03564.15 RLN88791.1 - 0.1 12.6 0.0 0.62 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) AAA PF00004.29 RLN88793.1 - 2.9e-21 76.3 0.0 5.5e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN88793.1 - 1.5e-05 25.5 0.0 3.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 RLN88793.1 - 0.00013 21.7 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RLN88793.1 - 0.00018 21.5 0.0 0.00037 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 RLN88793.1 - 0.00081 18.7 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 RLN88793.1 - 0.0033 17.7 0.0 0.7 10.2 0.0 3.3 2 1 2 4 4 4 1 AAA domain IstB_IS21 PF01695.17 RLN88793.1 - 0.031 14.0 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 RLN88793.1 - 0.037 13.6 0.0 0.077 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RLN88793.1 - 0.061 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 RLN88793.1 - 0.089 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.21 RLN88793.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 RLN88793.1 - 0.19 11.4 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.13 RLN88793.1 - 0.21 10.7 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mannosyl_trans3 PF11051.8 RLN88794.1 - 8.7e-35 120.4 0.0 1.7e-33 116.2 0.0 2.1 1 1 0 1 1 1 1 Mannosyltransferase putative LRR_4 PF12799.7 RLN88795.1 - 1.3e-18 66.8 13.1 0.00013 22.3 0.0 4.5 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN88795.1 - 2.7e-15 55.9 19.3 1.8e-06 27.6 2.9 4.6 2 2 2 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 RLN88795.1 - 1.1e-09 37.5 9.0 0.1 12.7 0.1 6.4 6 0 0 6 6 6 4 Leucine Rich repeat LRR_1 PF00560.33 RLN88795.1 - 9.4e-08 31.6 14.2 0.92 10.3 1.8 7.1 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_9 PF14580.6 RLN88795.1 - 0.0017 17.9 2.5 0.0097 15.4 0.8 2.2 1 1 0 2 2 2 1 Leucine-rich repeat V-SNARE_C PF12352.8 RLN88796.1 - 3.6e-05 24.0 0.7 3.6e-05 24.0 0.7 2.2 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 RLN88796.1 - 0.0026 18.1 5.5 0.023 15.1 0.5 2.2 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus APG6_N PF17675.1 RLN88796.1 - 0.04 14.4 1.7 0.068 13.7 1.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2408 PF10303.9 RLN88796.1 - 0.049 14.2 1.5 0.068 13.7 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Exonuc_VII_L PF02601.15 RLN88796.1 - 0.074 12.6 1.9 0.08 12.5 1.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF745 PF05335.13 RLN88796.1 - 0.12 12.1 1.9 0.19 11.5 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) FapA PF03961.13 RLN88796.1 - 0.13 10.8 3.0 0.17 10.5 3.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A CwsA PF10814.8 RLN88796.1 - 0.15 12.2 0.4 0.25 11.5 0.1 1.5 1 1 0 1 1 1 0 Cell wall synthesis protein CwsA DUF1640 PF07798.11 RLN88796.1 - 0.27 11.3 5.7 0.45 10.6 5.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF1664 PF07889.12 RLN88796.1 - 0.59 10.2 4.6 3.8 7.6 3.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) TolA_bind_tri PF16331.5 RLN88796.1 - 6.5 6.9 15.3 1.8 8.7 8.3 2.3 1 1 1 2 2 2 0 TolA binding protein trimerisation Pkinase_Tyr PF07714.17 RLN88797.1 - 2.1e-57 194.4 0.0 3.1e-57 193.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN88797.1 - 1.7e-38 132.5 0.0 2.7e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 RLN88797.1 - 0.04 12.9 0.1 0.077 11.9 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain XhlA PF10779.9 RLN88797.1 - 0.44 10.8 3.5 0.62 10.3 2.7 1.7 1 1 0 1 1 1 0 Haemolysin XhlA WD40 PF00400.32 RLN88798.1 - 3.8e-11 43.4 0.2 0.011 16.6 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 RLN88798.1 - 2.3e-07 29.7 0.2 7.4e-07 28.0 0.0 1.9 2 0 0 2 2 2 1 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 RLN88798.1 - 1.2e-06 28.7 0.0 2.5 8.5 0.0 5.3 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3605 PF12239.8 RLN88799.1 - 0.035 14.4 3.0 0.15 12.4 3.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3605) TGase_elicitor PF16683.5 RLN88800.1 - 1.1e-181 603.5 3.9 1.3e-181 603.2 3.9 1.1 1 0 0 1 1 1 1 Transglutaminase elicitor DUF3051 PF11252.8 RLN88801.1 - 0.053 13.2 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3051) CDC37_N PF03234.14 RLN88801.1 - 0.066 14.1 0.3 0.29 12.1 0.0 2.2 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Biotin_carb_C PF02785.19 RLN88804.1 - 4.3e-27 94.3 0.2 4.1e-26 91.2 0.1 2.5 2 1 0 2 2 2 1 Biotin carboxylase C-terminal domain CPSase_L_D2 PF02786.17 RLN88804.1 - 4.9e-25 88.3 0.0 8.4e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_lipoyl PF00364.22 RLN88804.1 - 1.6e-18 66.3 0.9 3.5e-18 65.2 0.9 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 RLN88804.1 - 2.5e-05 24.0 0.2 0.017 14.9 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 RLN88804.1 - 0.0035 16.9 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 RLN88804.1 - 0.0044 17.7 0.0 3.1 8.6 0.0 3.6 3 0 0 3 3 3 1 HlyD family secretion protein DUF2110 PF09883.9 RLN88804.1 - 0.13 11.9 0.4 0.36 10.4 0.1 1.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2110) OrfB_Zn_ribbon PF07282.11 RLN88805.1 - 0.066 13.1 1.9 0.29 11.1 1.9 2.1 1 1 0 1 1 1 0 Putative transposase DNA-binding domain DUF563 PF04577.14 RLN88805.1 - 0.074 13.2 0.1 0.2 11.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF563) HSF_DNA-bind PF00447.17 RLN88806.1 - 1.8e-21 76.5 3.2 2.9e-21 75.9 3.2 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding FYVE PF01363.21 RLN88807.1 - 4.5e-06 26.7 48.8 0.00073 19.6 14.9 3.5 3 0 0 3 3 3 3 FYVE zinc finger SE PF08491.10 RLN88807.1 - 0.0053 15.8 0.0 3.9 6.5 0.0 3.1 3 0 0 3 3 3 2 Squalene epoxidase FYVE_2 PF02318.16 RLN88807.1 - 2.9 8.1 35.8 0.15 12.2 6.9 4.2 3 1 0 3 3 3 0 FYVE-type zinc finger FYVE PF01363.21 RLN88808.1 - 0.015 15.4 10.6 0.031 14.4 10.6 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-C4pol PF14260.6 RLN88808.1 - 0.089 13.3 8.1 0.17 12.3 6.3 2.4 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta FYVE_2 PF02318.16 RLN88808.1 - 2.3 8.4 11.0 8.8 6.6 10.8 2.0 1 1 0 1 1 1 0 FYVE-type zinc finger C1_2 PF03107.16 RLN88808.1 - 3.7 7.9 8.7 0.5 10.7 4.5 1.8 2 0 0 2 2 2 0 C1 domain zf-piccolo PF05715.13 RLN88808.1 - 7.5 6.8 7.9 0.91 9.7 3.2 1.9 2 0 0 2 2 2 0 Piccolo Zn-finger FYVE PF01363.21 RLN88809.1 - 1.5 9.0 13.1 3.3 7.9 13.1 1.6 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN88809.1 - 3.7 7.8 12.5 14 5.9 12.6 1.9 1 1 0 1 1 1 0 FYVE-type zinc finger TFIID_NTD2 PF04494.15 RLN88810.1 - 1.2e-34 119.3 0.2 1.9e-34 118.7 0.2 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain WD40 PF00400.32 RLN88810.1 - 0.00041 21.1 0.3 1.1 10.2 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat SGL PF08450.12 RLN88811.1 - 5.2e-40 137.6 0.0 7.9e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 RLN88811.1 - 2.9e-06 27.3 0.0 0.00015 21.8 0.0 2.5 2 0 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.20 RLN88811.1 - 0.0076 16.4 0.0 0.075 13.2 0.0 2.4 2 1 0 2 2 2 1 Arylesterase Lactonase PF10282.9 RLN88811.1 - 0.013 14.7 0.0 0.035 13.4 0.0 1.7 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller ANAPC4_WD40 PF12894.7 RLN88811.1 - 0.17 12.2 0.0 0.68 10.3 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain GDC-P PF02347.16 RLN88813.1 - 2.6e-183 609.8 0.2 5.5e-166 552.7 0.1 3.1 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 RLN88813.1 - 8.2e-08 31.6 0.1 1.5e-06 27.5 0.1 2.5 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 RLN88813.1 - 0.01 15.1 0.1 0.026 13.8 0.1 1.6 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 RLN88813.1 - 0.017 13.7 0.1 2.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme DUF4689 PF15755.5 RLN88813.1 - 0.028 14.0 0.2 0.05 13.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4689) TraI PF07057.11 RLN88813.1 - 0.16 12.1 1.1 0.42 10.7 0.0 2.2 3 0 0 3 3 3 0 DNA helicase TraI CCDC53 PF10152.9 RLN88814.1 - 0.006 17.0 0.4 0.024 15.1 0.4 1.9 1 1 0 1 1 1 1 Subunit CCDC53 of WASH complex ENTH PF01417.20 RLN88815.1 - 3.5e-10 40.0 0.0 9.5e-10 38.6 0.0 1.7 1 1 0 1 1 1 1 ENTH domain ANTH PF07651.16 RLN88815.1 - 3e-08 33.0 0.4 4.6e-08 32.4 0.4 1.2 1 0 0 1 1 1 1 ANTH domain AA_permease_2 PF13520.6 RLN88818.1 - 2.3e-36 125.5 46.8 3.5e-36 125.0 46.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN88818.1 - 1.4e-26 93.2 48.2 9.3e-26 90.4 48.7 1.8 1 1 1 2 2 2 2 Amino acid permease MM_CoA_mutase PF01642.22 RLN88819.1 - 6e-235 780.6 0.4 7.3e-235 780.4 0.4 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 RLN88819.1 - 4.8e-14 52.4 0.0 1.5e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 B12 binding domain IMPDH PF00478.25 RLN88819.1 - 0.041 12.9 0.3 0.09 11.8 0.0 1.6 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain AAT PF03417.16 RLN88819.1 - 0.11 12.2 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Met_synt_B12 PF02965.17 RLN88820.1 - 1.2e-110 369.3 0.0 2.4e-110 368.3 0.0 1.5 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 RLN88820.1 - 6.4e-74 249.1 0.0 1.5e-73 247.9 0.0 1.7 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 RLN88820.1 - 1.2e-54 185.6 1.0 3.2e-54 184.2 1.0 1.8 1 0 0 1 1 1 1 Pterin binding enzyme B12-binding_2 PF02607.17 RLN88820.1 - 1.1e-23 83.4 0.1 1.1e-23 83.4 0.1 2.8 3 0 0 3 3 3 1 B12 binding domain B12-binding PF02310.19 RLN88820.1 - 4.2e-19 68.8 0.6 1.4e-18 67.0 0.6 2.0 1 0 0 1 1 1 1 B12 binding domain DUF2760 PF10816.8 RLN88820.1 - 0.066 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) Na_H_Exchanger PF00999.21 RLN88821.1 - 1.1e-12 47.4 37.0 3.8e-11 42.4 25.1 2.2 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family Pyr_redox_3 PF13738.6 RLN88821.1 - 0.0091 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase CRCB PF02537.15 RLN88822.1 - 3.5e-34 117.0 21.0 1.2e-17 64.0 3.7 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) DUF2628 PF10947.8 RLN88822.1 - 0.25 11.7 3.6 0.23 11.9 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2628) Phage_holin_5_2 PF16079.5 RLN88822.1 - 2.7 8.4 10.0 1.5 9.2 1.0 3.5 3 1 1 4 4 4 0 Phage holin family Hol44, in holin superfamily V XPA_C PF05181.12 RLN88823.1 - 1.6e-13 50.4 0.0 3e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 RLN88823.1 - 0.00032 20.7 1.8 0.00063 19.7 1.8 1.5 1 0 0 1 1 1 1 XPA protein N-terminal NdhM PF10664.9 RLN88823.1 - 0.05 13.9 0.2 0.078 13.2 0.2 1.3 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M zf-CSL PF05207.13 RLN88823.1 - 0.084 12.6 0.2 0.084 12.6 0.2 2.0 2 0 0 2 2 2 0 CSL zinc finger F-box-like PF12937.7 RLN88824.1 - 0.06 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 RLN88824.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 F-box domain EamA PF00892.20 RLN88825.1 - 2e-16 60.4 41.4 6.4e-09 36.1 15.6 3.0 2 1 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 RLN88825.1 - 1.5e-06 27.9 11.9 1.5e-06 27.9 11.9 1.9 2 1 0 2 2 2 1 Solute carrier family 35 PUNUT PF16913.5 RLN88825.1 - 0.00026 20.3 5.8 0.00073 18.9 5.8 1.9 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport TPT PF03151.16 RLN88825.1 - 0.0036 16.7 5.4 0.0063 15.9 5.2 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family DUF3955 PF13127.6 RLN88825.1 - 0.01 15.6 3.9 0.01 15.6 3.9 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF3955) Halogen_Hydrol PF10112.9 RLN88825.1 - 0.54 10.2 3.5 36 4.3 0.1 3.3 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein U-box PF04564.15 RLN88826.1 - 4.5e-12 46.0 0.1 8.2e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 U-box domain C2 PF00168.30 RLN88826.1 - 1.8e-07 31.4 0.0 9.7e-07 29.0 0.0 2.2 2 0 0 2 2 2 1 C2 domain zf-NOSIP PF15906.5 RLN88826.1 - 0.0016 18.5 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 RLN88826.1 - 0.0018 18.0 0.1 0.0033 17.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Beach PF02138.18 RLN88827.1 - 4.4e-91 305.1 0.0 6.8e-91 304.5 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain ELMO_CED12 PF04727.13 RLN88827.1 - 2.4e-32 112.5 0.0 4.7e-32 111.5 0.0 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family DUF4704 PF15787.5 RLN88827.1 - 4e-15 55.8 0.0 9.7e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 RLN88827.1 - 3.8e-09 36.5 0.0 7.6e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 RLN88827.1 - 6.2e-08 32.9 0.0 2.2e-07 31.2 0.0 2.0 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 RLN88827.1 - 0.0033 18.2 3.9 4.2 8.4 0.2 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Methyltransf_4 PF02390.17 RLN88828.1 - 1e-37 129.2 0.0 1.7e-21 76.5 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Mob1_phocein PF03637.17 RLN88829.1 - 4.7e-62 208.9 0.1 7e-62 208.4 0.1 1.3 1 0 0 1 1 1 1 Mob1/phocein family Phtf-FEM1B_bdg PF12129.8 RLN88830.1 - 8.4e-20 71.2 0.2 2.3e-19 69.7 0.0 1.8 2 0 0 2 2 2 1 Male germ-cell putative homeodomain transcription factor LicD PF04991.13 RLN88830.1 - 6.4e-09 36.3 0.5 1e-08 35.7 0.5 1.3 1 0 0 1 1 1 1 LicD family AAA PF00004.29 RLN88831.1 - 4.4e-36 124.2 0.1 4.9e-31 107.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 RLN88831.1 - 2.2e-17 62.8 0.1 4.7e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 RLN88831.1 - 2e-12 47.3 0.4 2.6e-05 24.3 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RLN88831.1 - 9.5e-12 45.4 3.2 0.0093 16.2 0.1 4.8 3 2 1 4 4 4 3 AAA domain AAA_16 PF13191.6 RLN88831.1 - 1.2e-10 42.0 0.8 0.00018 21.9 0.0 3.8 2 2 1 3 3 3 2 AAA ATPase domain Torsin PF06309.11 RLN88831.1 - 1.7e-10 41.1 0.0 4.3e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 Torsin AAA_2 PF07724.14 RLN88831.1 - 2.7e-10 40.6 1.4 0.0002 21.5 0.7 3.9 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 RLN88831.1 - 6.8e-09 35.9 0.0 0.0038 17.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 RLN88831.1 - 8.1e-08 32.2 0.2 0.014 15.1 0.1 3.1 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 RLN88831.1 - 1.7e-07 31.6 0.0 0.0012 19.2 0.0 2.9 3 0 0 3 3 2 2 RNA helicase ResIII PF04851.15 RLN88831.1 - 4.2e-06 26.9 0.2 0.0036 17.3 0.0 3.3 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_18 PF13238.6 RLN88831.1 - 7.9e-06 26.4 4.8 0.063 13.8 0.0 4.1 4 1 0 4 4 3 2 AAA domain PhoH PF02562.16 RLN88831.1 - 1.8e-05 24.3 0.1 0.36 10.2 0.0 3.3 3 0 0 3 3 3 2 PhoH-like protein Sigma54_activat PF00158.26 RLN88831.1 - 2.1e-05 24.3 0.0 0.082 12.6 0.0 3.3 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_33 PF13671.6 RLN88831.1 - 2.7e-05 24.3 0.1 0.0025 18.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RLN88831.1 - 7.7e-05 23.1 1.1 1.7 9.0 0.0 3.6 2 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 RLN88831.1 - 0.0001 22.1 0.0 0.11 12.2 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_3 PF07726.11 RLN88831.1 - 0.00015 21.7 0.0 0.33 10.8 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RLN88831.1 - 0.00023 20.9 0.1 0.00073 19.3 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_30 PF13604.6 RLN88831.1 - 0.00034 20.4 2.8 1.8 8.2 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 RLN88831.1 - 0.00036 20.1 0.0 0.34 10.4 0.0 2.8 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 RLN88831.1 - 0.00044 20.8 3.9 0.92 10.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain KAP_NTPase PF07693.14 RLN88831.1 - 0.00067 19.0 0.2 0.17 11.1 0.0 3.0 2 1 0 3 3 3 1 KAP family P-loop domain TsaE PF02367.17 RLN88831.1 - 0.00083 19.4 0.0 0.51 10.3 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 RLN88831.1 - 0.00091 19.8 0.9 5.1 7.6 0.0 3.7 3 0 0 3 3 3 0 ABC transporter Zeta_toxin PF06414.12 RLN88831.1 - 0.00094 18.5 1.9 0.36 10.1 0.0 3.0 3 0 0 3 3 2 1 Zeta toxin AAA_28 PF13521.6 RLN88831.1 - 0.0011 19.2 0.1 1.8 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 RLN88831.1 - 0.0014 17.7 0.0 0.099 11.7 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 RLN88831.1 - 0.0023 18.0 0.0 1 9.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 RLN88831.1 - 0.0026 17.2 0.1 0.12 11.8 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 RLN88831.1 - 0.003 16.8 0.0 0.059 12.6 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain Viral_helicase1 PF01443.18 RLN88831.1 - 0.0037 17.0 0.0 3.2 7.4 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 RLN88831.1 - 0.0077 16.0 1.7 1.7 8.3 0.0 3.3 4 0 0 4 4 3 1 AAA domain CPT PF07931.12 RLN88831.1 - 0.014 15.3 0.0 0.036 13.9 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AFG1_ATPase PF03969.16 RLN88831.1 - 0.014 14.4 0.0 4 6.2 0.0 2.5 3 0 0 3 3 2 0 AFG1-like ATPase NB-ARC PF00931.22 RLN88831.1 - 0.014 14.6 4.8 3.4 6.8 0.0 3.2 2 1 0 2 2 2 0 NB-ARC domain FlxA PF14282.6 RLN88831.1 - 0.021 14.8 0.6 0.17 11.9 0.3 2.5 2 0 0 2 2 2 0 FlxA-like protein AAA_11 PF13086.6 RLN88831.1 - 0.022 14.5 12.2 0.45 10.2 0.0 4.1 3 1 0 3 3 2 0 AAA domain IPT PF01745.16 RLN88831.1 - 0.036 13.5 0.1 2.3 7.5 0.0 2.7 2 0 0 2 2 2 0 Isopentenyl transferase NACHT PF05729.12 RLN88831.1 - 0.049 13.6 0.2 2.8 7.8 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 RLN88831.1 - 0.052 13.1 2.4 4.9 6.7 0.1 3.7 2 1 1 3 3 3 0 AAA domain DUF2075 PF09848.9 RLN88831.1 - 0.065 12.5 1.4 3.2 6.9 0.0 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 RLN88831.1 - 0.067 12.5 6.5 0.28 10.5 0.0 3.5 3 1 0 3 3 3 0 KaiC Cytidylate_kin PF02224.18 RLN88831.1 - 0.073 12.8 1.4 10 5.8 0.0 2.9 3 0 0 3 3 2 0 Cytidylate kinase NTPase_1 PF03266.15 RLN88831.1 - 0.092 12.7 2.1 3.3 7.6 0.1 3.4 4 0 0 4 4 4 0 NTPase AAA_6 PF12774.7 RLN88831.1 - 0.1 11.6 0.2 1 8.2 0.0 2.3 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region RsgA_GTPase PF03193.16 RLN88831.1 - 0.14 12.0 0.5 14 5.6 0.1 3.5 3 1 1 4 4 3 0 RsgA GTPase AAA_29 PF13555.6 RLN88831.1 - 0.17 11.6 0.1 28 4.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Atg14 PF10186.9 RLN88831.1 - 1.1 8.3 4.6 2.2 7.3 4.6 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ion_trans PF00520.31 RLN88833.1 - 1.1e-18 67.3 7.3 1.5e-18 66.9 7.3 1.1 1 0 0 1 1 1 1 Ion transport protein FYVE PF01363.21 RLN88834.1 - 4.3e-15 55.6 11.3 1.3e-14 54.1 11.3 1.9 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN88834.1 - 0.015 15.6 4.8 0.015 15.6 4.8 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger CAP_N PF01213.19 RLN88834.1 - 0.76 9.2 3.6 4.6 6.6 0.7 2.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal ILVD_EDD PF00920.21 RLN88835.1 - 5.5e-218 724.8 1.1 6.3e-218 724.6 1.1 1.0 1 0 0 1 1 1 1 Dehydratase family FeoA PF04023.14 RLN88835.1 - 0.0013 18.9 0.1 1.1 9.6 0.0 3.1 3 0 0 3 3 3 2 FeoA domain ILVD_EDD PF00920.21 RLN88836.1 - 5.2e-208 691.9 1.0 5.8e-208 691.7 1.0 1.0 1 0 0 1 1 1 1 Dehydratase family FeoA PF04023.14 RLN88836.1 - 0.00052 20.2 0.2 0.63 10.3 0.0 3.2 3 0 0 3 3 3 2 FeoA domain 2CSK_N PF08521.10 RLN88837.1 - 0.041 14.0 2.9 0.076 13.1 2.9 1.4 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal V_ATPase_I PF01496.19 RLN88837.1 - 0.17 9.8 5.0 0.22 9.4 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3138 PF11336.8 RLN88837.1 - 1.9 7.0 3.7 3.1 6.3 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF1515 PF07439.11 RLN88837.1 - 4.7 7.3 5.7 24 5.0 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Myb_DNA-bind_3 PF12776.7 RLN88838.1 - 0.022 15.7 1.4 0.04 14.9 0.2 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Arrestin_C PF02752.22 RLN88839.1 - 5.8e-10 39.7 0.0 1e-08 35.7 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 RLN88839.1 - 8.6e-07 29.1 0.0 1.6e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain CENP-B_dimeris PF09026.10 RLN88840.1 - 0.047 14.1 13.2 0.092 13.2 13.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop53 PF07767.11 RLN88840.1 - 0.13 11.6 9.7 0.2 11.0 9.7 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Hamartin PF04388.12 RLN88840.1 - 0.35 9.5 8.5 0.43 9.2 8.5 1.1 1 0 0 1 1 1 0 Hamartin protein EBV-NA3 PF05009.12 RLN88840.1 - 0.68 9.4 7.9 1.1 8.7 7.9 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) TRAP_alpha PF03896.16 RLN88840.1 - 1.1 8.4 4.7 1.7 7.8 4.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Astro_capsid_p PF12226.8 RLN88840.1 - 2.7 7.1 8.6 3.9 6.5 8.6 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF4267 PF14087.6 RLN88842.1 - 0.023 14.8 0.1 5.5 7.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) DUF5305 PF17231.2 RLN88842.1 - 0.24 10.8 0.0 0.31 10.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Pkinase PF00069.25 RLN88844.1 - 2.5e-50 171.3 0.0 4.5e-50 170.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN88844.1 - 2e-44 151.8 0.0 2.8e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Adeno_E3_CR2 PF02439.15 RLN88844.1 - 0.022 14.5 0.2 0.044 13.5 0.2 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Neurensin PF14927.6 RLN88844.1 - 0.13 11.9 0.4 0.39 10.4 0.4 1.7 1 1 0 1 1 1 0 Neurensin Kdo PF06293.14 RLN88844.1 - 0.16 11.3 0.1 0.25 10.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_Ag35 PF03286.14 RLN88845.1 - 0.003 17.4 5.8 0.0051 16.6 5.8 1.3 1 0 0 1 1 1 1 Pox virus Ag35 surface protein DUF4820 PF16091.5 RLN88845.1 - 0.011 15.1 1.8 0.011 15.1 1.8 2.1 3 0 0 3 3 2 0 Domain of unknown function (DUF4820) Nop14 PF04147.12 RLN88845.1 - 0.018 13.3 10.2 0.024 12.9 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 RLN88845.1 - 0.023 14.6 5.6 0.037 13.9 5.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region SKA1 PF07160.12 RLN88845.1 - 0.026 14.4 0.5 0.058 13.2 0.5 1.6 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 MPP6 PF10175.9 RLN88845.1 - 0.034 14.7 2.5 0.034 14.7 2.5 1.6 2 0 0 2 2 1 0 M-phase phosphoprotein 6 TFB6 PF17110.5 RLN88845.1 - 0.037 13.8 1.2 0.062 13.0 1.2 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RXT2_N PF08595.11 RLN88845.1 - 0.07 13.1 6.0 0.13 12.3 6.0 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal TFIIA PF03153.13 RLN88845.1 - 0.095 12.7 4.7 0.11 12.4 4.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Paf1 PF03985.13 RLN88845.1 - 0.13 11.2 8.2 0.19 10.7 8.2 1.2 1 0 0 1 1 1 0 Paf1 NOA36 PF06524.12 RLN88845.1 - 0.14 11.5 12.8 0.18 11.1 12.8 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 RLN88845.1 - 0.18 9.9 15.7 0.25 9.4 15.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 RLN88845.1 - 0.3 10.7 6.3 0.62 9.7 6.3 1.5 1 0 0 1 1 1 0 FAM176 family BUD22 PF09073.10 RLN88845.1 - 0.3 10.4 8.1 0.4 10.0 8.1 1.2 1 0 0 1 1 1 0 BUD22 TRAP_alpha PF03896.16 RLN88845.1 - 0.41 9.8 4.3 0.76 8.9 4.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cytomega_UL84 PF06284.11 RLN88845.1 - 0.47 8.8 4.2 0.64 8.4 4.2 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Nucleo_P87 PF07267.11 RLN88845.1 - 0.53 9.1 1.7 0.55 9.0 1.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Astro_capsid_p PF12226.8 RLN88845.1 - 0.66 9.1 14.9 1 8.4 14.9 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop53 PF07767.11 RLN88845.1 - 1.1 8.6 9.0 1.9 7.8 9.0 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF4611 PF15387.6 RLN88845.1 - 1.6 9.0 14.0 0.12 12.7 8.9 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4611) Sporozoite_P67 PF05642.11 RLN88845.1 - 2 6.4 4.8 2.8 5.9 4.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.12 RLN88845.1 - 3.7 7.2 13.9 5.7 6.6 13.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 RLN88845.1 - 4.1 6.9 10.5 6.1 6.4 10.5 1.2 1 0 0 1 1 1 0 PPP4R2 DUF2457 PF10446.9 RLN88845.1 - 5.5 6.0 22.5 8.4 5.4 22.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.10 RLN88845.1 - 6.1 7.3 23.9 13 6.3 23.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SDA1 PF05285.12 RLN88845.1 - 6.5 6.1 15.3 0.14 11.6 9.1 1.3 2 0 0 2 2 1 0 SDA1 FYDLN_acid PF09538.10 RLN88845.1 - 6.5 7.5 15.7 0.61 10.8 10.7 1.8 2 0 0 2 2 1 0 Protein of unknown function (FYDLN_acid) RNA_polI_A34 PF08208.11 RLN88845.1 - 8.3 6.4 9.6 14 5.7 9.6 1.4 1 1 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Carn_acyltransf PF00755.20 RLN88846.1 - 2.5e-137 459.0 0.0 1.5e-135 453.2 0.0 2.0 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase LSM PF01423.22 RLN88847.1 - 2e-18 65.8 1.1 2.5e-18 65.5 1.1 1.1 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.17 RLN88847.1 - 0.0037 17.1 0.6 0.0065 16.3 0.6 1.4 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain KH_6 PF15985.5 RLN88848.1 - 1.3e-14 54.2 0.1 2e-14 53.6 0.1 1.3 1 0 0 1 1 1 1 KH domain DUF1128 PF06569.11 RLN88848.1 - 0.0071 16.3 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1128) EF-hand_8 PF13833.6 RLN88849.1 - 2.1e-13 49.9 0.9 9.3e-12 44.6 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 RLN88849.1 - 8.3e-10 39.0 2.0 0.0015 19.0 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 RLN88849.1 - 6.1e-05 22.3 0.8 0.00071 18.9 0.2 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RLN88849.1 - 0.00036 20.2 1.1 1.1 9.4 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 RLN88849.1 - 0.079 12.5 0.1 0.34 10.5 0.1 2.0 1 0 0 1 1 1 0 EF hand Porin_3 PF01459.22 RLN88850.1 - 1e-39 136.7 14.4 1.1e-39 136.5 14.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin Adeno_E1B_19K PF01691.16 RLN88850.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen CS PF04969.16 RLN88851.1 - 3e-15 57.0 0.0 5.8e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 RLN88851.1 - 1.9e-14 53.4 0.1 4.7e-14 52.1 0.1 1.8 1 1 0 1 1 1 1 N-terminal conserved domain of Nudc. Hid1 PF12722.7 RLN88851.1 - 0.019 13.1 2.4 0.029 12.5 2.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1943 PF09172.11 RLN88851.1 - 0.03 13.6 0.4 0.051 12.8 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Nop25 PF09805.9 RLN88851.1 - 1.7 9.1 14.7 0.23 11.9 9.9 1.9 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Presenilin PF01080.17 RLN88851.1 - 5.3 5.7 4.5 8.2 5.1 4.5 1.3 1 0 0 1 1 1 0 Presenilin Fe-S_biosyn PF01521.20 RLN88853.1 - 6.1e-17 61.8 0.0 6.7e-17 61.7 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SRP14 PF02290.15 RLN88854.1 - 1.7e-10 41.1 0.0 2.8e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle 14kD protein DUF442 PF04273.13 RLN88854.1 - 0.13 12.3 0.1 0.33 11.1 0.1 1.6 1 0 0 1 1 1 0 Putative phosphatase (DUF442) SSXT PF05030.12 RLN88855.1 - 3.1e-21 74.7 2.0 8e-21 73.4 2.0 1.8 1 0 0 1 1 1 1 SSXT protein (N-terminal region) AAA PF00004.29 RLN88855.1 - 1.2e-05 25.7 0.2 0.00044 20.7 0.0 3.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN88855.1 - 0.027 14.8 0.0 0.079 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RLN88855.1 - 0.038 14.4 2.0 0.17 12.3 0.1 3.1 2 1 0 2 2 2 0 AAA ATPase domain Mitoc_mL59 PF18126.1 RLN88856.1 - 9.8e-06 25.9 4.7 0.00063 20.1 1.6 2.5 2 1 0 2 2 2 2 Mitochondrial ribosomal protein mL59 DM PF00751.18 RLN88856.1 - 0.31 11.0 4.1 0.74 9.8 1.1 2.5 2 0 0 2 2 2 0 DM DNA binding domain NADHdh_A3 PF14987.6 RLN88857.1 - 0.0051 17.1 0.2 0.017 15.4 0.2 1.8 1 0 0 1 1 1 1 NADH dehydrogenase 1 alpha subcomplex subunit 3 Macro PF01661.21 RLN88858.1 - 3.4e-13 49.7 0.0 5.5e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Macro domain Peptidase_S28 PF05577.12 RLN88859.1 - 4.7e-72 243.1 0.0 6.3e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 RLN88859.1 - 0.047 13.3 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2920 PF11144.8 RLN88859.1 - 0.067 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) GntP_permease PF02447.16 RLN88859.1 - 0.11 11.2 0.0 1.4 7.5 0.0 2.1 2 0 0 2 2 2 0 GntP family permease Ribosomal_L11_N PF03946.14 RLN88861.1 - 4.4e-21 74.5 0.6 6.7e-21 73.9 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 RLN88861.1 - 9.7e-17 61.2 0.1 1.5e-16 60.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain EF-hand_1 PF00036.32 RLN88862.1 - 2.7e-13 48.4 2.1 8.4e-06 25.0 0.8 4.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RLN88862.1 - 5e-13 47.8 4.1 0.00081 19.1 0.6 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 RLN88862.1 - 1.2e-12 47.4 3.3 3e-08 33.4 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 RLN88862.1 - 2.7e-12 47.0 0.7 5.3e-05 23.6 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN88862.1 - 1.4e-07 30.7 2.9 0.0019 17.6 0.8 3.2 3 0 0 3 3 3 2 EF hand TerB PF05099.13 RLN88862.1 - 0.0005 20.1 0.5 0.0005 20.1 0.5 2.0 3 0 0 3 3 3 1 Tellurite resistance protein TerB EF-hand_9 PF14658.6 RLN88862.1 - 0.0022 18.3 0.3 2 8.8 0.0 3.1 2 1 1 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 RLN88862.1 - 0.01 15.8 0.4 0.077 12.9 0.1 2.2 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand PurS PF02700.14 RLN88862.1 - 0.14 12.3 0.0 0.67 10.2 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosylformylglycinamidine (FGAM) synthase HTH_47 PF16221.5 RLN88862.1 - 0.17 11.4 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 winged helix-turn-helix Peptidase_C2 PF00648.21 RLN88863.1 - 2.4e-44 151.6 0.0 6.8e-44 150.1 0.0 1.7 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 RLN88863.1 - 5e-17 62.5 0.0 5.8e-06 26.6 0.0 6.2 6 1 0 6 6 6 4 Calpain large subunit, domain III DUF4228 PF14009.6 RLN88863.1 - 0.041 14.3 0.6 0.14 12.6 0.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4228) Myb_DNA-binding PF00249.31 RLN88864.1 - 3.4e-29 100.8 1.2 2.5e-14 53.2 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN88864.1 - 1e-18 67.3 0.2 2.1e-13 50.3 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN88864.1 - 1.8e-07 30.9 0.1 0.00042 20.1 0.0 2.2 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 RLN88864.1 - 0.075 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 SLIDE Peptidase_M1_N PF17900.1 RLN88865.1 - 1.8e-23 83.7 0.0 2.1e-23 83.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 RLN88865.1 - 0.077 13.0 0.0 0.097 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) ApbA PF02558.16 RLN88866.1 - 1.2e-12 47.7 0.5 4.2e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 RLN88866.1 - 0.00019 21.6 0.1 0.00038 20.7 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal F420_oxidored PF03807.17 RLN88866.1 - 3.6 8.2 4.5 5.3 7.7 0.2 2.7 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Xpo1 PF08389.12 RLN88867.1 - 2.4e-22 79.6 1.0 6.5e-21 75.0 0.0 3.3 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 RLN88867.1 - 8.4e-06 25.6 0.0 3.4e-05 23.7 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain MNR PF15718.5 RLN88867.1 - 0.024 12.8 0.1 0.041 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein moonraker Ion_trans PF00520.31 RLN88868.1 - 3.4e-44 150.9 36.4 1.5e-12 47.3 8.0 5.8 4 2 0 4 4 4 4 Ion transport protein Ion_trans_2 PF07885.16 RLN88868.1 - 1.1e-26 92.6 30.3 7.6e-10 38.6 4.0 4.7 4 0 0 4 4 4 4 Ion channel IRK PF01007.20 RLN88868.1 - 0.0014 18.5 6.2 7.7 6.3 0.2 4.3 4 0 0 4 4 4 3 Inward rectifier potassium channel transmembrane domain Tubulin PF00091.25 RLN88869.1 - 1.7e-63 214.4 0.0 2.4e-63 213.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RLN88869.1 - 1.2e-49 167.6 0.1 1.9e-49 167.0 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RLN88869.1 - 0.011 15.4 0.0 0.057 13.1 0.0 2.1 2 0 0 2 2 2 0 Tubulin domain GMC_oxred_N PF00732.19 RLN88870.1 - 7.2e-40 137.2 0.0 1.3e-39 136.3 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 RLN88870.1 - 0.00013 22.1 0.0 0.00033 20.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 RLN88870.1 - 0.0046 16.2 0.2 0.079 12.2 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RLN88870.1 - 0.0061 16.2 1.0 0.23 11.0 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 RLN88870.1 - 0.0081 15.4 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 RLN88870.1 - 0.0082 14.9 0.5 0.017 13.9 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 RLN88870.1 - 0.014 14.7 0.0 0.03 13.6 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RLN88870.1 - 0.015 14.3 0.1 0.022 13.8 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 RLN88870.1 - 0.021 14.1 0.1 0.029 13.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 RLN88870.1 - 0.048 12.5 0.0 0.076 11.9 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.24 RLN88870.1 - 0.12 11.4 0.6 1.4 7.9 0.2 2.0 2 0 0 2 2 2 0 FAD binding domain PLAC8 PF04749.17 RLN88872.1 - 9.7e-19 68.2 17.3 2.2e-18 67.1 17.3 1.6 1 0 0 1 1 1 1 PLAC8 family Fringe PF02434.16 RLN88872.1 - 5.4e-11 42.4 0.4 9.4e-11 41.6 0.4 1.3 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 RLN88872.1 - 0.00041 20.2 0.1 0.00064 19.6 0.1 1.2 1 0 0 1 1 1 1 Galactosyltransferase Env-gp36 PF09590.10 RLN88872.1 - 0.01 14.3 0.0 0.016 13.6 0.0 1.2 1 0 0 1 1 1 0 Lentivirus surface glycoprotein PLAC8 PF04749.17 RLN88873.1 - 8.8e-45 151.8 52.7 1.3e-18 67.9 18.8 3.3 3 0 0 3 3 3 3 PLAC8 family SLC35F PF06027.12 RLN88874.1 - 2.2e-09 37.2 10.0 2.5e-09 37.1 10.0 1.0 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 RLN88874.1 - 0.00025 21.2 7.7 0.00031 20.9 7.7 1.1 1 0 0 1 1 1 1 EamA-like transporter family UAA PF08449.11 RLN88874.1 - 0.00045 19.5 4.0 0.00052 19.3 4.0 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 RLN88874.1 - 0.0018 17.7 0.5 0.0029 17.0 0.1 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family DUF2542 PF10808.8 RLN88876.1 - 0.0015 19.0 2.0 18 5.9 0.0 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF2542) ApoO PF09769.9 RLN88876.1 - 0.097 12.6 1.9 28 4.7 0.1 3.6 3 1 0 3 3 3 0 Apolipoprotein O FliE PF02049.18 RLN88876.1 - 0.22 11.7 15.1 1.2 9.3 0.3 4.1 4 1 0 4 4 4 0 Flagellar hook-basal body complex protein FliE Phage_holin_6_1 PF09682.10 RLN88876.1 - 1.6 9.2 11.2 6.1 7.3 0.1 4.4 5 0 0 5 5 5 0 Bacteriophage holin of superfamily 6 (Holin_LLH) PLDc PF00614.22 RLN88876.1 - 5.2 7.4 11.8 36 4.8 2.2 4.2 4 1 0 4 4 4 0 Phospholipase D Active site motif TFIIA PF03153.13 RLN88877.1 - 0.057 13.4 16.4 0.063 13.3 16.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 RLN88877.1 - 0.59 9.4 13.5 0.66 9.2 13.5 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 RLN88877.1 - 0.93 7.6 18.2 1.1 7.4 18.2 1.1 1 0 0 1 1 1 0 Nop14-like family NPR3 PF03666.13 RLN88877.1 - 1.6 7.4 4.8 2.1 7.1 4.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SDA1 PF05285.12 RLN88877.1 - 2.1 7.7 16.2 2.4 7.5 16.2 1.1 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 RLN88877.1 - 2.4 8.0 16.7 5.1 6.9 16.7 1.5 1 1 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.11 RLN88877.1 - 3.1 7.8 10.6 4.7 7.2 10.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal PPP4R2 PF09184.11 RLN88877.1 - 6.2 6.3 15.2 6.9 6.2 15.2 1.2 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 RLN88877.1 - 6.4 6.0 16.5 8.3 5.6 16.5 1.2 1 0 0 1 1 1 0 NOA36 protein RPN2_C PF18004.1 RLN88877.1 - 6.6 6.6 7.7 9.5 6.1 7.7 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DHHC PF01529.20 RLN88878.1 - 2.1e-32 112.0 3.7 2.1e-32 112.0 3.7 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 RLN88878.1 - 8.4e-25 87.2 7.4 1.2e-10 41.8 0.2 3.9 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN88878.1 - 1.4e-22 79.4 1.7 3.3e-09 36.8 0.2 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN88878.1 - 2.9e-17 62.2 7.3 1.7e-07 31.4 0.1 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 RLN88878.1 - 4.4e-14 52.7 2.2 0.00011 22.6 0.0 6.0 3 1 3 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN88878.1 - 1.4e-11 43.5 1.2 0.0024 18.2 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat UcrQ PF02939.16 RLN88879.1 - 1.2e-07 31.6 0.0 1.3e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 RLN88879.1 - 2.1e-05 24.8 0.0 2.8e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 Ysc84 PF04366.12 RLN88880.1 - 1.1e-35 122.1 0.1 1.6e-35 121.6 0.1 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator zf-ribbon_3 PF13248.6 RLN88880.1 - 0.034 13.6 2.0 0.091 12.2 2.0 1.8 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2HC5 PF06221.13 RLN88880.1 - 0.047 13.7 2.5 0.67 10.0 0.5 2.3 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type OrfB_Zn_ribbon PF07282.11 RLN88880.1 - 0.079 12.9 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Exo_endo_phos PF03372.23 RLN88884.1 - 3.9e-11 42.9 0.1 6.4e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4337 PF14235.6 RLN88884.1 - 0.099 12.8 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) CcmH PF03918.14 RLN88884.1 - 0.17 11.2 1.2 0.35 10.2 1.2 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Peptidase_M56 PF05569.11 RLN88884.1 - 1.5 7.9 4.1 0.78 8.9 0.0 2.0 2 0 0 2 2 2 0 BlaR1 peptidase M56 Ank_2 PF12796.7 RLN88885.1 - 4.1e-09 36.9 0.0 7.8e-08 32.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN88885.1 - 3e-08 34.1 0.1 0.00019 21.9 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN88885.1 - 6.6e-08 32.2 0.0 0.014 15.9 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 RLN88885.1 - 1.4e-05 25.3 0.0 0.0015 18.9 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 RLN88885.1 - 9.1e-05 22.7 0.1 0.039 14.3 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ndc1_Nup PF09531.10 RLN88885.1 - 4.4 5.9 7.7 4.7 5.8 7.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Fez1 PF06818.15 RLN88886.1 - 0.0085 16.6 15.0 0.23 11.9 0.6 2.3 2 0 0 2 2 2 2 Fez1 DUF421 PF04239.12 RLN88886.1 - 0.013 15.3 1.7 0.013 15.3 1.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF421) UPF0242 PF06785.11 RLN88886.1 - 0.046 13.8 14.4 0.04 14.0 5.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Cob_adeno_trans PF01923.18 RLN88886.1 - 0.19 11.8 8.3 0.5 10.5 2.6 3.1 3 1 0 3 3 3 0 Cobalamin adenosyltransferase ERM PF00769.19 RLN88886.1 - 0.4 10.5 17.9 3.5 7.4 12.0 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family TolA_bind_tri PF16331.5 RLN88886.1 - 0.92 9.6 15.0 0.15 12.2 4.1 3.5 3 1 1 4 4 3 0 TolA binding protein trimerisation EMP24_GP25L PF01105.24 RLN88886.1 - 0.93 9.4 6.8 0.5 10.3 0.1 2.8 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Suppressor_APC PF11414.8 RLN88886.1 - 0.99 9.5 15.2 0.34 11.0 0.9 3.6 2 1 1 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein DUF2451 PF10474.9 RLN88886.1 - 1.4 8.7 6.4 0.2 11.4 2.0 1.7 2 1 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) Exonuc_VII_L PF02601.15 RLN88886.1 - 1.6 8.2 11.6 7.4 6.0 6.7 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit APG6_N PF17675.1 RLN88886.1 - 2.4 8.7 23.7 3.5 8.2 2.0 3.0 2 1 1 3 3 3 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 RLN88886.1 - 2.5 8.4 14.2 7.2 6.9 6.4 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF5623 PF18536.1 RLN88886.1 - 2.5 8.4 6.3 8.8 6.7 6.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5623) DUF5320 PF17253.2 RLN88886.1 - 4.3 8.5 6.0 23 6.2 1.2 3.2 2 1 0 3 3 2 0 Family of unknown function (DUF5320) FapA PF03961.13 RLN88886.1 - 5 5.6 8.5 3.9 6.0 4.3 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 RLN88886.1 - 5.1 4.9 9.9 2.5 5.9 4.3 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family NBP1 PF08537.10 RLN88886.1 - 5.1 6.4 12.7 8.2 5.7 0.4 2.4 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 Ax_dynein_light PF10211.9 RLN88886.1 - 5.9 6.8 17.4 0.86 9.5 9.3 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain GAS PF13851.6 RLN88886.1 - 8.7 5.6 22.9 8.4 5.7 12.8 2.8 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding SPRY PF00622.28 RLN88887.1 - 5.1e-09 36.3 0.0 1.2e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 SPRY domain DUF1640 PF07798.11 RLN88887.1 - 0.93 9.5 16.2 3.1 7.8 16.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Histidinol_dh PF00815.20 RLN88887.1 - 6.1 5.7 5.5 12 4.8 5.5 1.4 1 0 0 1 1 1 0 Histidinol dehydrogenase ABC_tran PF00005.27 RLN88888.1 - 4.9e-30 104.8 0.0 7.9e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 RLN88888.1 - 4.2e-15 56.1 0.0 5.3e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 RLN88888.1 - 6.4e-08 32.3 0.0 4.7e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RLN88888.1 - 3.8e-05 24.1 0.2 0.00012 22.5 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RLN88888.1 - 0.00038 20.7 0.1 0.32 11.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 RLN88888.1 - 0.0033 17.4 0.0 0.013 15.5 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain IstB_IS21 PF01695.17 RLN88888.1 - 0.0052 16.5 0.0 0.39 10.4 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 RLN88888.1 - 0.0064 16.1 0.0 0.48 10.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RLN88888.1 - 0.0069 16.8 0.4 0.22 11.9 0.4 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 RLN88888.1 - 0.011 14.5 0.0 0.023 13.5 0.0 1.4 1 1 0 1 1 1 0 Predicted ATPase of the ABC class AAA_30 PF13604.6 RLN88888.1 - 0.012 15.4 0.5 0.16 11.6 0.5 2.2 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 RLN88888.1 - 0.013 15.7 0.2 0.18 12.0 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 RLN88888.1 - 0.016 14.9 0.0 0.046 13.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 RLN88888.1 - 0.017 15.1 0.1 0.14 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 RLN88888.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 RLN88888.1 - 0.12 12.1 0.1 6.7 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system FUSC PF04632.12 RLN88889.1 - 6.6 5.1 21.2 10 4.5 21.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CBS PF00571.28 RLN88890.1 - 3.1e-05 24.3 0.0 4.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 CBS domain Cation_efflux PF01545.21 RLN88891.1 - 9.5e-44 149.5 8.3 1.2e-43 149.2 8.3 1.1 1 0 0 1 1 1 1 Cation efflux family C1_2 PF03107.16 RLN88892.1 - 0.0081 16.5 2.8 0.018 15.3 2.8 1.6 1 0 0 1 1 1 1 C1 domain FYVE PF01363.21 RLN88892.1 - 0.018 15.1 16.1 0.039 14.1 16.1 1.5 1 0 0 1 1 1 0 FYVE zinc finger RRM_1 PF00076.22 RLN88893.1 - 2e-41 139.6 0.0 1.7e-17 63.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 RLN88893.1 - 0.0003 20.7 0.0 0.0013 18.7 0.0 2.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 RLN88893.1 - 0.0004 20.4 0.1 1.4 9.1 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif PHM7_cyt PF14703.6 RLN88893.1 - 0.0014 18.9 0.0 0.22 11.7 0.0 2.9 3 0 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 RLN88893.1 - 0.018 15.1 0.0 0.21 11.7 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif OB_RNB PF08206.11 RLN88893.1 - 0.082 12.6 0.3 18 5.1 0.0 2.7 2 0 0 2 2 2 0 Ribonuclease B OB domain RRM_occluded PF16842.5 RLN88893.1 - 0.21 11.5 0.0 0.46 10.4 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif PDEase_I PF00233.19 RLN88894.1 - 4.2e-60 203.4 0.1 7.1e-60 202.7 0.1 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF1455 PF07306.11 RLN88894.1 - 0.11 12.5 0.2 0.23 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) RhodobacterPufX PF11511.8 RLN88894.1 - 6.3 6.5 9.0 6.5 6.4 0.7 3.4 2 2 1 3 3 3 0 Intrinsic membrane protein PufX DUF3357 PF11837.8 RLN88895.1 - 0.19 12.2 1.4 0.38 11.2 0.6 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) DUF805 PF05656.14 RLN88895.1 - 0.61 10.5 2.4 1.7 9.1 2.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF805) FYVE PF01363.21 RLN88896.1 - 7.4e-11 42.0 7.3 1.8e-10 40.8 7.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE PF01363.21 RLN88897.1 - 0.0034 17.5 13.1 0.0034 17.5 13.1 1.7 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 RLN88897.1 - 0.046 13.9 6.7 0.1 12.8 6.7 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger ArfGap PF01412.18 RLN88897.1 - 1.7 8.7 7.2 0.9 9.6 4.9 1.8 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf FYVE PF01363.21 RLN88899.1 - 0.0056 16.8 4.9 0.0056 16.8 4.9 2.1 2 0 0 2 2 2 1 FYVE zinc finger MRP-S28 PF10213.9 RLN88899.1 - 0.039 14.4 0.0 2.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit protein IMS PF00817.20 RLN88900.1 - 1.1e-36 126.0 0.0 2e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 RLN88900.1 - 2.1e-15 57.4 0.0 5.9e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 RLN88900.1 - 1.7e-05 24.1 0.1 0.00012 21.4 0.0 2.6 2 0 0 2 2 2 1 Ubiquitin binding region IMS_HHH PF11798.8 RLN88900.1 - 0.00033 20.8 0.0 0.00095 19.4 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif GTP_cyclohydroI PF01227.22 RLN88901.1 - 1.4e-77 259.2 1.4 1.7e-77 258.9 1.4 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 RLN88901.1 - 0.0025 17.9 0.0 0.0046 17.1 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein RNA_binding PF01877.17 RLN88901.1 - 0.037 14.3 0.1 0.076 13.3 0.1 1.5 1 0 0 1 1 1 0 RNA binding SAVED PF18145.1 RLN88901.1 - 0.18 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 SMODS-associated and fused to various effectors sensor domain Pkinase_Tyr PF07714.17 RLN88902.1 - 1.2e-08 34.6 0.0 1.9e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN88902.1 - 2.2e-05 24.0 0.0 3.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Phage_mat-A PF03863.13 RLN88902.1 - 0.11 11.4 0.1 0.34 9.8 0.0 1.7 1 1 1 2 2 2 0 Phage maturation protein Acyltransferase PF01553.21 RLN88903.1 - 2e-05 24.3 0.0 3.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase RCC1 PF00415.18 RLN88904.1 - 1.1e-56 189.3 17.3 2.9e-15 56.6 0.1 8.8 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN88904.1 - 2.7e-30 103.5 32.8 5e-07 29.4 1.5 6.9 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat EF-hand_6 PF13405.6 RLN88905.1 - 7.5e-12 44.2 12.0 0.51 10.4 0.0 8.6 8 0 0 8 8 8 4 EF-hand domain EF-hand_7 PF13499.6 RLN88905.1 - 3e-09 37.2 4.6 0.64 10.5 0.0 7.4 7 0 0 7 7 7 3 EF-hand domain pair EF-hand_1 PF00036.32 RLN88905.1 - 4.4e-05 22.7 16.4 1.7 8.4 0.1 7.4 8 0 0 8 8 8 3 EF hand RST PF12174.8 RLN88905.1 - 0.026 14.5 17.2 4 7.4 0.0 7.9 7 2 1 8 8 8 0 RCD1-SRO-TAF4 (RST) plant domain EAP30 PF04157.16 RLN88905.1 - 0.097 11.9 0.1 0.42 9.8 0.1 2.1 1 0 0 1 1 1 0 EAP30/Vps36 family Rad21_Rec8_N PF04825.13 RLN88906.1 - 3.1e-40 136.8 0.0 6.2e-40 135.8 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 RLN88906.1 - 3.6e-13 48.6 0.2 1.3e-12 46.8 0.2 2.0 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein CNDH2_N PF06278.11 RLN88906.1 - 0.049 13.9 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal AMP-binding_C PF13193.6 RLN88907.1 - 2.6e-05 25.1 0.1 8.3e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 RLN88908.1 - 2.6e-44 151.5 0.0 3.6e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 RLN88908.1 - 5.4e-17 61.4 8.1 4.5e-12 45.7 1.0 2.4 2 0 0 2 2 2 2 Acetyl-coenzyme A synthetase N-terminus Arm PF00514.23 RLN88909.1 - 1.3e-31 107.6 9.7 9.7e-09 35.0 0.0 7.0 7 0 0 7 7 7 5 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 RLN88909.1 - 1.3e-06 28.3 4.7 0.3 11.1 0.1 4.8 3 1 1 5 5 5 3 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 RLN88909.1 - 9.7e-05 22.3 1.1 1.9 8.9 0.0 5.4 6 0 0 6 6 6 2 HEAT repeat HEAT_PBS PF03130.16 RLN88909.1 - 0.00019 21.8 15.8 5.4 8.0 0.0 7.5 8 1 0 8 8 8 2 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 RLN88909.1 - 0.00027 21.4 20.8 0.00045 20.7 0.7 5.7 6 1 1 7 7 7 2 HEAT-like repeat HEAT_2 PF13646.6 RLN88909.1 - 0.013 15.9 16.8 0.33 11.4 0.2 4.6 1 1 3 5 5 5 0 HEAT repeats Keratin_2_head PF16208.5 RLN88910.1 - 5.2 7.2 13.7 6.5 6.9 13.7 1.1 1 0 0 1 1 1 0 Keratin type II head Lamprin PF06403.11 RLN88910.1 - 8.9 6.3 20.7 0.37 10.8 14.6 1.7 2 0 0 2 2 2 0 Lamprin Pkinase_Tyr PF07714.17 RLN88911.1 - 2.5e-56 190.9 0.0 1.9e-42 145.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN88911.1 - 2.2e-50 171.5 0.0 8.3e-38 130.3 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Arm PF00514.23 RLN88911.1 - 5e-25 86.7 26.1 0.00018 21.4 0.0 13.4 15 0 0 15 15 15 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN88911.1 - 2.6e-05 24.6 35.5 0.00071 20.0 0.2 8.5 8 2 2 10 10 10 2 HEAT-like repeat HEAT PF02985.22 RLN88911.1 - 0.0001 22.3 25.5 0.79 10.2 0.0 11.5 13 0 0 13 13 12 1 HEAT repeat DUF3361 PF11841.8 RLN88911.1 - 0.0013 18.7 0.6 9.7 6.1 0.0 5.8 7 1 0 7 7 7 1 Domain of unknown function (DUF3361) TM1506 PF08973.10 RLN88911.1 - 0.0038 16.9 0.4 13 5.4 0.0 4.9 3 1 3 6 6 6 1 Domain of unknown function (DUF1893) TPR_16 PF13432.6 RLN88911.1 - 0.033 14.8 2.9 0.2 12.3 0.1 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat HEAT_2 PF13646.6 RLN88911.1 - 0.043 14.2 0.2 0.043 14.2 0.2 8.2 4 2 7 11 11 11 0 HEAT repeats Kinase-like PF14531.6 RLN88911.1 - 0.071 12.4 0.0 4.3 6.6 0.0 2.6 2 0 0 2 2 2 0 Kinase-like UME PF08064.13 RLN88911.1 - 0.091 12.7 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 UME (NUC010) domain Pkinase PF00069.25 RLN88912.1 - 2.4e-09 36.9 0.0 2.8e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF3585 PF12130.8 RLN88913.1 - 0.029 14.5 3.0 0.053 13.7 3.0 1.4 1 0 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain DUF3035 PF11233.8 RLN88914.1 - 0.19 12.0 11.6 0.13 12.6 9.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3035) TFIIA PF03153.13 RLN88914.1 - 3.2 7.7 12.6 3.8 7.4 12.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S46 PF10459.9 RLN88914.1 - 3.4 6.2 13.6 4.1 5.9 13.6 1.0 1 0 0 1 1 1 0 Peptidase S46 STAS_2 PF13466.6 RLN88914.1 - 4.9 7.6 7.7 8.5 6.8 1.4 2.6 2 1 1 3 3 3 0 STAS domain SIR2_2 PF13289.6 RLN88915.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 SIR2-like domain Dimer_Tnp_hAT PF05699.14 RLN88916.1 - 0.0069 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MULE PF10551.9 RLN88917.1 - 4.5e-09 36.6 0.1 2.5e-08 34.2 0.1 2.1 2 0 0 2 2 2 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 RLN88917.1 - 0.0018 18.1 1.8 0.026 14.2 0.1 2.6 2 1 1 3 3 3 1 Transposase RRM_5 PF13893.6 RLN88917.1 - 0.017 14.7 0.1 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5575 PF17738.1 RLN88917.1 - 0.051 12.6 0.0 0.081 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5575) TTL PF03133.15 RLN88920.1 - 3.4e-56 190.6 0.1 5.2e-56 189.9 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family CRAL_TRIO PF00650.20 RLN88921.1 - 1.7e-30 105.8 0.0 2.5e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain PrsW-protease PF13367.6 RLN88921.1 - 0.092 12.2 1.1 0.16 11.4 1.1 1.3 1 0 0 1 1 1 0 PrsW family intramembrane metalloprotease Tam41_Mmp37 PF09139.11 RLN88922.1 - 2.2e-89 300.1 0.1 3.3e-89 299.5 0.1 1.3 1 1 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Sec61_beta PF03911.16 RLN88923.1 - 1.3e-18 66.7 0.1 1.3e-18 66.7 0.1 2.4 3 0 0 3 3 3 1 Sec61beta family DNA_pol_phi PF04931.13 RLN88924.1 - 1.9e-86 290.9 39.5 1.9e-86 290.9 39.5 5.6 2 2 0 3 3 3 1 DNA polymerase phi SOBP PF15279.6 RLN88925.1 - 2.8 8.5 6.0 1.4 9.4 3.9 1.4 1 1 0 1 1 1 0 Sine oculis-binding protein Ran_BP1 PF00638.18 RLN88926.1 - 1.4e-10 41.5 0.1 1.5e-10 41.4 0.1 1.0 1 0 0 1 1 1 1 RanBP1 domain UPF0058 PF01893.16 RLN88926.1 - 0.021 15.1 0.0 0.045 14.0 0.0 1.5 1 1 1 2 2 2 0 Uncharacterised protein family UPF0058 BTB_2 PF02214.22 RLN88929.1 - 5.8e-11 42.6 0.0 1.1e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain His_Phos_2 PF00328.22 RLN88931.1 - 5e-13 49.2 0.0 1.2e-10 41.3 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Herpes_UL95 PF03038.14 RLN88931.1 - 0.12 11.4 0.4 0.37 9.9 0.3 1.6 1 1 0 2 2 2 0 UL95 family His_Phos_2 PF00328.22 RLN88932.1 - 1.4e-15 57.5 0.1 1.4e-10 41.1 0.1 2.6 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) PPR_long PF17177.4 RLN88933.1 - 2.2e-06 27.2 0.6 1.8e-05 24.2 0.2 2.1 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 RLN88933.1 - 1.6e-05 25.3 7.6 0.066 13.7 0.1 3.5 1 1 1 3 3 3 2 Tetratricopeptide repeat PPR PF01535.20 RLN88933.1 - 0.00024 21.1 0.0 0.33 11.3 0.0 3.0 4 0 0 4 4 3 1 PPR repeat PPR_3 PF13812.6 RLN88933.1 - 0.00045 20.2 0.0 0.013 15.6 0.0 2.8 2 1 1 3 3 3 1 Pentatricopeptide repeat domain TPR_4 PF07721.14 RLN88933.1 - 0.00073 19.9 4.3 0.077 13.7 0.2 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN88933.1 - 0.0034 18.1 8.7 0.85 10.6 0.0 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat PPR_2 PF13041.6 RLN88933.1 - 0.0056 16.8 0.0 0.14 12.4 0.0 2.6 3 0 0 3 3 3 1 PPR repeat family TPR_7 PF13176.6 RLN88933.1 - 0.065 13.3 1.0 5.5 7.3 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN88933.1 - 0.067 13.4 0.7 6.8 7.0 0.2 3.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR_1 PF12854.7 RLN88933.1 - 0.078 12.7 0.0 0.93 9.2 0.0 2.5 3 0 0 3 3 3 0 PPR repeat TPR_10 PF13374.6 RLN88933.1 - 0.08 12.8 0.4 0.81 9.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Retinal PF15449.6 RLN88933.1 - 0.12 10.1 0.2 0.17 9.6 0.2 1.1 1 0 0 1 1 1 0 Retinal protein DUF742 PF05331.11 RLN88933.1 - 0.13 12.1 1.9 0.25 11.2 1.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF742) GST_C PF00043.25 RLN88933.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TPR_16 PF13432.6 RLN88933.1 - 0.68 10.6 5.6 12 6.6 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_63 PF03200.16 RLN88934.1 - 5.7e-167 556.4 1.0 6.4e-165 549.6 1.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 RLN88934.1 - 7.4e-31 108.0 0.0 1.5e-30 107.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 RLN88934.1 - 0.062 12.1 0.5 0.25 10.1 0.0 2.0 2 0 0 2 2 2 0 Trehalase OrfB_Zn_ribbon PF07282.11 RLN88935.1 - 0.00025 20.9 6.5 0.031 14.2 0.4 3.1 3 0 0 3 3 3 2 Putative transposase DNA-binding domain DUF3365 PF11845.8 RLN88935.1 - 0.011 16.0 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) MFS_1_like PF12832.7 RLN88937.1 - 1.5e-40 139.3 10.1 1.7e-40 139.1 10.1 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RLN88937.1 - 2.3e-17 62.9 34.5 9.3e-12 44.5 13.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 RLN88937.1 - 9.3e-07 27.9 5.1 1.2e-06 27.6 5.1 1.3 1 1 0 1 1 1 1 LacY proton/sugar symporter Nuc_H_symport PF03825.16 RLN88937.1 - 0.0014 17.7 6.4 0.0019 17.3 6.4 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter MFS_3 PF05977.13 RLN88937.1 - 0.0073 14.7 10.5 0.012 14.0 10.5 1.3 1 1 0 1 1 1 1 Transmembrane secretion effector Caveolin PF01146.17 RLN88937.1 - 3.9 7.5 5.8 2.6 8.0 0.1 2.9 3 0 0 3 3 3 0 Caveolin MFS_1_like PF12832.7 RLN88938.1 - 1e-35 123.3 4.9 5.3e-35 121.0 4.9 1.8 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RLN88938.1 - 3e-12 46.2 16.1 4.6e-12 45.5 16.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Nuc_H_symport PF03825.16 RLN88938.1 - 3.5e-08 32.9 10.6 6.2e-08 32.0 10.6 1.5 1 1 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 RLN88938.1 - 4.3e-06 25.8 7.6 4.3e-06 25.8 7.6 2.0 2 1 0 2 2 2 1 LacY proton/sugar symporter MFS_2 PF13347.6 RLN88938.1 - 8.5e-06 24.6 10.5 0.0028 16.3 5.3 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein Rx_N PF18052.1 RLN88939.1 - 1.5 9.2 8.1 0.8 10.0 0.9 2.7 3 0 0 3 3 3 0 Rx N-terminal domain DUF4140 PF13600.6 RLN88939.1 - 6.1 7.4 7.8 0.52 10.8 0.4 2.7 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DRIM PF07539.12 RLN88940.1 - 1.2e-124 416.9 4.1 1.2e-124 416.9 4.1 5.5 6 0 0 6 6 6 1 Down-regulated in metastasis HEAT PF02985.22 RLN88940.1 - 8.1e-08 31.9 28.2 0.6 10.5 0.2 11.0 11 0 0 11 11 11 4 HEAT repeat BLM10_mid PF16507.5 RLN88940.1 - 0.0012 17.6 0.1 0.0031 16.3 0.1 1.7 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region YL1 PF05764.13 RLN88940.1 - 0.0024 18.1 14.1 0.0024 18.1 14.1 2.5 2 0 0 2 2 2 1 YL1 nuclear protein CLASP_N PF12348.8 RLN88940.1 - 0.038 13.6 0.2 1.2 8.7 0.0 3.4 3 0 0 3 3 3 0 CLASP N terminal RRN3 PF05327.11 RLN88940.1 - 0.05 12.1 2.1 0.16 10.5 2.1 1.8 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.13 RLN88940.1 - 1.4 8.8 8.8 2 8.2 5.9 2.8 2 0 0 2 2 2 0 Sigma-70, non-essential region Band_7_C PF16200.5 RLN88941.1 - 5.2e-29 100.1 0.3 1.2e-28 98.9 0.3 1.7 1 0 0 1 1 1 1 C-terminal region of band_7 Dak1_2 PF13684.6 RLN88941.1 - 0.011 14.8 1.2 0.011 14.8 1.2 1.1 1 0 0 1 1 1 0 Dihydroxyacetone kinase family ABC_sub_bind PF04392.12 RLN88941.1 - 0.023 13.9 0.7 0.027 13.7 0.7 1.1 1 0 0 1 1 1 0 ABC transporter substrate binding protein Neur_chan_memb PF02932.16 RLN88942.1 - 3.9e-05 23.8 3.0 5.8e-05 23.3 1.7 1.8 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 RLN88942.1 - 0.09 12.2 0.0 0.9 8.9 0.0 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel ligand binding domain Cas_Csy4 PF09618.10 RLN88943.1 - 0.017 15.2 1.4 0.029 14.5 1.0 1.5 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) Peptidase_C1 PF00112.23 RLN88944.1 - 0.00064 19.9 0.1 0.3 11.1 0.0 2.3 2 0 0 2 2 2 2 Papain family cysteine protease ABC2_membrane PF01061.24 RLN88945.1 - 5.5e-67 225.2 71.3 2.1e-39 135.1 30.0 3.5 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 RLN88945.1 - 4e-35 121.3 0.0 1.2e-16 61.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 RLN88945.1 - 3.5e-08 33.5 0.3 0.0088 16.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 RLN88945.1 - 1.1e-06 28.7 0.0 0.21 11.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN88945.1 - 1.3e-06 28.9 0.1 0.03 14.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 RLN88945.1 - 3.6e-06 26.6 4.3 0.043 13.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN88945.1 - 3.6e-05 24.3 0.8 0.081 13.4 0.7 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RLN88945.1 - 7.1e-05 23.1 0.1 0.31 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain PDR_CDR PF06422.12 RLN88945.1 - 0.00025 20.9 0.2 0.00025 20.9 0.2 3.7 4 0 0 4 4 3 1 CDR ABC transporter AAA_25 PF13481.6 RLN88945.1 - 0.00051 19.7 0.5 0.35 10.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN88945.1 - 0.001 18.4 0.5 0.25 10.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin DUF87 PF01935.17 RLN88945.1 - 0.015 15.4 5.4 2.2 8.3 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain cobW PF02492.19 RLN88945.1 - 0.016 14.8 0.8 0.4 10.3 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 RLN88945.1 - 0.017 15.2 0.6 7.2 6.7 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase PDR_assoc PF08370.11 RLN88945.1 - 0.035 13.8 0.2 0.035 13.8 0.2 5.0 4 1 1 5 5 4 0 Plant PDR ABC transporter associated AAA PF00004.29 RLN88945.1 - 0.041 14.3 0.2 1.4 9.4 0.1 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 RLN88945.1 - 0.047 13.1 0.3 13 5.2 0.1 3.3 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 RLN88945.1 - 0.058 13.1 2.5 3.9 7.1 0.8 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RLN88945.1 - 0.096 12.4 0.1 7.9 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 RLN88945.1 - 0.18 11.8 2.2 3 7.9 0.6 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 RLN88945.1 - 0.23 11.2 2.3 2.3 8.0 0.5 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 RLN88945.1 - 0.59 10.0 4.9 7 6.5 0.4 2.5 2 0 0 2 2 2 0 NACHT domain ABC_ATPase PF09818.9 RLN88945.1 - 1.4 7.6 3.2 1.9 7.2 0.9 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class ABC2_membrane PF01061.24 RLN88946.1 - 4.5e-59 199.4 55.9 2.1e-36 125.4 25.6 3.0 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN88946.1 - 1.1e-35 123.1 0.2 3.1e-17 63.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 RLN88946.1 - 4.2e-08 33.3 0.2 0.0055 16.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 RLN88946.1 - 2.4e-07 30.9 0.0 0.2 11.4 0.0 3.4 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN88946.1 - 1.7e-05 25.3 3.3 0.12 12.7 0.0 3.8 3 1 1 4 4 4 2 AAA ATPase domain AAA_23 PF13476.6 RLN88946.1 - 1.9e-05 25.3 0.3 0.11 13.0 0.2 2.7 3 0 0 3 3 2 2 AAA domain PDR_CDR PF06422.12 RLN88946.1 - 9.6e-05 22.2 0.1 0.012 15.5 0.0 3.2 2 0 0 2 2 2 1 CDR ABC transporter AAA_29 PF13555.6 RLN88946.1 - 9.8e-05 22.0 10.3 0.017 14.8 0.1 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN88946.1 - 0.00016 22.0 0.0 0.36 11.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 RLN88946.1 - 0.00025 20.7 0.2 0.13 11.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN88946.1 - 0.0016 17.8 0.5 0.31 10.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin DUF815 PF05673.13 RLN88946.1 - 0.0041 16.3 0.2 0.011 15.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 RLN88946.1 - 0.011 15.5 0.1 2.3 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 RLN88946.1 - 0.017 15.2 0.4 8.3 6.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 RLN88946.1 - 0.017 14.6 0.3 6.3 6.2 0.1 3.7 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 RLN88946.1 - 0.019 15.4 0.1 1.6 9.2 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 RLN88946.1 - 0.045 13.7 1.8 2.6 8.1 0.3 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 RLN88946.1 - 0.07 13.2 4.8 2.5 8.2 1.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain cobW PF02492.19 RLN88946.1 - 0.12 11.9 1.2 0.75 9.4 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 RLN88946.1 - 0.16 11.7 1.9 4 7.2 0.4 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 RLN88946.1 - 0.19 12.3 0.0 37 4.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RLN88946.1 - 0.2 12.1 0.2 23 5.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 RLN88946.1 - 0.21 11.3 0.0 23 4.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RLN88946.1 - 0.87 9.5 5.0 8 6.4 0.4 2.7 2 0 0 2 2 2 0 NACHT domain ABC2_membrane PF01061.24 RLN88947.1 - 1e-28 100.2 30.3 1e-28 100.2 30.3 2.0 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN88947.1 - 9.3e-05 22.3 0.1 9.3e-05 22.3 0.1 2.8 2 1 0 2 2 2 1 CDR ABC transporter RIC1 PF07064.13 RLN88948.1 - 6.8e-18 65.0 0.3 3e-17 62.9 0.3 2.1 1 1 0 1 1 1 1 RIC1 ACBP PF00887.19 RLN88948.1 - 7.9e-10 38.8 0.0 1.9e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein PDZ PF00595.24 RLN88948.1 - 4.1e-05 23.8 0.1 9.5e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RLN88948.1 - 7e-05 22.6 0.4 0.00019 21.2 0.4 1.8 1 0 0 1 1 1 1 PDZ domain ANAPC4_WD40 PF12894.7 RLN88948.1 - 0.0013 18.9 0.0 0.077 13.3 0.0 3.4 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PDR_CDR PF06422.12 RLN88949.1 - 3.9e-08 33.1 0.0 9.6e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 CDR ABC transporter ABC2_membrane PF01061.24 RLN88949.1 - 2.7e-07 30.2 7.8 4.8e-07 29.4 7.8 1.4 1 0 0 1 1 1 1 ABC-2 type transporter PDR_assoc PF08370.11 RLN88949.1 - 0.016 14.9 0.2 0.052 13.3 0.2 1.8 1 0 0 1 1 1 0 Plant PDR ABC transporter associated DUF3533 PF12051.8 RLN88949.1 - 1 8.2 5.7 0.45 9.4 2.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) YchF-GTPase_C PF06071.13 RLN88950.1 - 2.3e-09 37.3 0.0 1.2e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF933) TB2_DP1_HVA22 PF03134.19 RLN88952.1 - 5.3e-12 45.5 0.9 1e-11 44.6 0.9 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Glyco_hydro_77 PF02446.17 RLN88952.1 - 0.11 11.3 0.1 0.62 8.9 0.0 1.9 2 0 0 2 2 2 0 4-alpha-glucanotransferase MerE PF05052.12 RLN88953.1 - 0.00085 19.2 2.0 0.00085 19.2 2.0 2.2 2 0 0 2 2 2 1 MerE protein FAM176 PF14851.6 RLN88953.1 - 0.0011 18.6 2.9 0.019 14.6 0.1 2.5 2 0 0 2 2 2 2 FAM176 family HupE_UreJ_2 PF13795.6 RLN88953.1 - 0.024 14.3 0.4 0.024 14.3 0.4 2.5 3 0 0 3 3 3 0 HupE / UreJ protein FoP_duplication PF13865.6 RLN88954.1 - 1.5e-18 67.1 13.6 1.5e-18 67.1 13.6 2.6 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 DBINO PF13892.6 RLN88954.1 - 0.47 10.8 3.3 0.61 10.4 2.7 1.4 1 1 0 1 1 1 0 DNA-binding domain DUF5580 PF17743.1 RLN88954.1 - 1.1 7.8 5.1 1.3 7.4 5.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Guanylate_cyc PF00211.20 RLN88955.1 - 5.4e-08 32.7 0.0 9.4e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HTH_OrfB_IS605 PF12323.8 RLN88956.1 - 9.1e-06 25.1 0.0 2.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain OrfB_IS605 PF01385.19 RLN88956.1 - 0.016 15.4 0.2 0.046 13.9 0.1 1.8 2 0 0 2 2 2 0 Probable transposase Tugs PF17840.1 RLN88956.1 - 0.15 12.2 0.2 0.4 10.9 0.2 1.7 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain FAD_binding_8 PF08022.12 RLN88957.1 - 1.9e-19 69.8 0.0 3.2e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 RLN88957.1 - 1.4e-17 64.0 11.6 3.4e-17 62.7 11.6 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 RLN88957.1 - 5e-12 46.2 0.0 1.1e-11 45.0 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 RLN88957.1 - 0.00015 22.4 0.1 0.93 10.2 0.0 2.4 1 1 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 RLN88957.1 - 0.0013 19.0 0.0 0.0033 17.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain SpoIIE PF07228.12 RLN88959.1 - 4.2e-14 52.9 1.0 1.9e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 RLN88959.1 - 0.00079 19.1 0.1 0.038 13.6 0.0 2.4 2 0 0 2 2 2 1 Protein phosphatase 2C CBS PF00571.28 RLN88959.1 - 0.00087 19.7 0.1 0.28 11.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain PPTA PF01239.22 RLN88960.1 - 1.5e-30 103.9 11.1 2.4e-06 27.1 0.1 6.0 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_14 PF13428.6 RLN88960.1 - 0.026 15.3 0.1 1.9 9.5 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2098 PF09871.9 RLN88960.1 - 0.43 10.9 4.3 0.77 10.1 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) STIMATE PF12400.8 RLN88961.1 - 5.9e-24 85.0 4.6 5.9e-24 85.0 4.6 1.5 1 1 0 1 1 1 1 STIMATE family bZIP_2 PF07716.15 RLN88962.1 - 2.3e-07 30.8 0.5 2.3e-07 30.8 0.5 2.2 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 RLN88962.1 - 3.2e-06 27.1 0.6 3.2e-06 27.1 0.6 1.7 2 0 0 2 2 2 1 bZIP transcription factor Mitofilin PF09731.9 RLN88963.1 - 3 6.6 9.1 3.6 6.3 9.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Dimer_Tnp_hAT PF05699.14 RLN88965.1 - 1.5e-11 43.9 0.1 7.4e-11 41.7 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region adh_short_C2 PF13561.6 RLN88967.1 - 6.9e-07 29.1 0.1 7.3e-06 25.7 0.0 2.5 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RLN88967.1 - 0.01 15.3 0.0 0.39 10.1 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase BAR_2 PF10455.9 RLN88967.1 - 0.057 12.6 0.1 0.091 11.9 0.1 1.3 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Hydrolase_4 PF12146.8 RLN88969.1 - 4e-13 49.2 0.0 9.1e-12 44.7 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN88969.1 - 2.4e-10 40.5 0.0 1.1e-07 31.7 0.2 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN88969.1 - 1.5e-05 25.7 0.0 2.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 RLN88969.1 - 0.004 16.8 0.0 0.017 14.8 0.0 1.8 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DUF915 PF06028.11 RLN88969.1 - 0.017 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Ndr PF03096.14 RLN88969.1 - 0.034 12.9 0.0 0.057 12.1 0.0 1.3 1 0 0 1 1 1 0 Ndr family Abhydro_lipase PF04083.16 RLN88969.1 - 0.069 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region PH PF00169.29 RLN88970.1 - 7.8e-50 167.8 0.0 3.3e-09 37.2 0.0 11.4 11 0 0 11 11 11 9 PH domain PH_11 PF15413.6 RLN88970.1 - 1.2e-07 32.1 0.0 5 7.6 0.0 7.7 9 0 0 9 9 9 3 Pleckstrin homology domain PH_6 PF15406.6 RLN88970.1 - 2e-05 24.8 2.9 0.099 12.9 0.0 6.2 6 0 0 6 6 6 1 Pleckstrin homology domain ADH_zinc_N PF00107.26 RLN88971.1 - 6.2e-24 84.4 0.0 1e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN88971.1 - 1e-11 46.0 0.0 2.1e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN88971.1 - 9.3e-09 35.2 0.9 4.3e-08 33.0 0.6 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 RLN88971.1 - 0.011 15.9 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Aldedh PF00171.22 RLN88972.1 - 3e-64 217.2 0.0 3.6e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.25 RLN88976.1 - 1.6e-65 221.1 0.0 2e-65 220.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN88976.1 - 2.8e-47 161.2 0.0 3.4e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN88976.1 - 0.00097 18.0 0.0 0.0016 17.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN88976.1 - 0.0013 18.7 2.1 0.015 15.2 1.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 RLN88976.1 - 0.1 11.5 0.0 0.48 9.3 0.0 1.8 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase UPF0506 PF11703.8 RLN88977.1 - 0.57 10.6 6.8 0.057 13.8 2.0 1.7 2 0 0 2 2 2 0 UPF0506 RCC1 PF00415.18 RLN88978.1 - 1.4e-15 57.6 15.0 4.1e-07 30.5 0.1 5.4 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN88978.1 - 1.3e-12 47.1 18.3 6.9e-05 22.5 1.5 5.9 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat GAD-like PF08887.11 RLN88978.1 - 0.16 11.8 0.1 33 4.3 0.0 3.1 3 0 0 3 3 3 0 GAD-like domain Metallophos PF00149.28 RLN88979.1 - 0.0022 18.6 0.1 4 7.9 0.2 2.8 2 1 1 3 3 3 2 Calcineurin-like phosphoesterase ATG16 PF08614.11 RLN88981.1 - 0.0072 16.6 31.8 0.019 15.2 4.6 4.7 4 1 0 4 4 4 3 Autophagy protein 16 (ATG16) FlxA PF14282.6 RLN88981.1 - 0.082 12.9 6.7 22 5.1 0.8 3.7 3 0 0 3 3 3 0 FlxA-like protein Rab5-bind PF09311.11 RLN88981.1 - 0.34 10.2 22.8 0.026 13.9 2.8 3.4 3 1 0 4 4 4 0 Rabaptin-like protein BLOC1_2 PF10046.9 RLN88981.1 - 6.1 7.2 12.5 12 6.3 0.1 4.1 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YabA PF06156.13 RLN88981.1 - 7.8 7.2 14.5 41 4.9 0.0 4.6 3 1 0 4 4 4 0 Initiation control protein YabA DUF1697 PF08002.11 RLN88982.1 - 0.13 12.8 0.6 0.45 11.0 0.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1697) DCD PF06559.11 RLN88983.1 - 0.009 14.8 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) DcpS_C PF11969.8 RLN88984.1 - 2.3e-27 95.7 1.7 2.6e-27 95.5 0.4 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 RLN88984.1 - 2.4e-13 50.8 0.0 5.1e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal P16-Arc PF04699.14 RLN88985.1 - 1.3e-27 97.1 0.3 1.9e-27 96.6 0.3 1.2 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) TF_Zn_Ribbon PF08271.12 RLN88985.1 - 0.02 14.4 2.1 0.044 13.3 2.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding DNA_RNApol_7kD PF03604.13 RLN88985.1 - 0.027 14.1 0.5 0.057 13.1 0.5 1.6 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_10 PF10058.9 RLN88985.1 - 0.064 13.0 0.4 5.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn-ribbon_8 PF09723.10 RLN88985.1 - 0.11 12.7 2.1 0.11 12.6 0.6 1.9 2 0 0 2 2 2 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 RLN88985.1 - 0.16 11.9 1.1 0.34 10.9 1.1 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn_ribbon_SprT PF17283.2 RLN88985.1 - 0.17 11.8 1.7 11 6.0 0.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zinc_ribbon_2 PF13240.6 RLN88985.1 - 1.2 8.9 4.3 36 4.2 4.2 2.3 1 1 0 1 1 1 0 zinc-ribbon domain Abhydrolase_3 PF07859.13 RLN88986.1 - 1.9e-10 41.0 0.7 4.6e-06 26.6 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN88986.1 - 3e-05 24.7 0.5 4.4e-05 24.2 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 RLN88986.1 - 0.00049 19.1 0.0 0.018 13.9 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family LIDHydrolase PF10230.9 RLN88986.1 - 0.013 15.1 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase WD40 PF00400.32 RLN88987.1 - 2.6e-14 53.4 0.5 0.00035 21.3 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN88987.1 - 3.7e-11 43.2 0.0 0.0047 17.2 0.0 3.5 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 RLN88987.1 - 0.00046 20.0 0.8 2 8.5 0.2 3.6 3 1 0 3 3 3 2 PQQ enzyme repeat Ge1_WD40 PF16529.5 RLN88987.1 - 0.0022 17.0 0.2 0.93 8.4 0.0 2.9 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein GSDH PF07995.11 RLN88987.1 - 0.041 13.2 0.0 3 7.0 0.0 2.1 2 0 0 2 2 2 0 Glucose / Sorbosone dehydrogenase WD40_like PF17005.5 RLN88987.1 - 0.051 12.9 0.0 0.14 11.5 0.0 1.7 1 1 0 1 1 1 0 WD40-like domain PQQ_3 PF13570.6 RLN88987.1 - 0.063 13.8 1.3 28 5.4 0.1 3.7 4 0 0 4 4 4 0 PQQ-like domain NUMOD1 PF07453.13 RLN88987.1 - 0.23 11.8 0.8 0.83 10.0 0.0 2.3 3 0 0 3 3 3 0 NUMOD1 domain Proteasome_A_N PF10584.9 RLN88987.1 - 0.46 10.2 2.9 1.4 8.7 0.0 3.1 3 1 0 3 3 3 0 Proteasome subunit A N-terminal signature Hexapep PF00132.24 RLN88988.1 - 3.1e-14 52.0 6.3 9e-11 41.1 4.1 3.2 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 RLN88988.1 - 3.3e-11 42.7 7.0 1.2e-09 37.7 2.9 3.0 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 RLN88988.1 - 7.6e-11 42.1 0.0 1.3e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase ABATE PF07336.11 RLN88988.1 - 0.07 13.8 0.7 0.1 13.3 0.7 1.2 1 0 0 1 1 1 0 Putative stress-induced transcription regulator 2_5_RNA_ligase2 PF13563.6 RLN88989.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily Pkinase PF00069.25 RLN88990.1 - 2.1e-49 168.3 0.0 3.4e-49 167.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN88990.1 - 4.3e-42 144.2 0.0 5.8e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DIOX_N PF14226.6 RLN88990.1 - 1.2e-22 80.9 0.0 1.9e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 RLN88990.1 - 3.7e-17 62.6 0.0 1.1e-16 61.1 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CoatB PF10389.9 RLN88990.1 - 0.022 14.6 1.1 0.022 14.6 1.1 2.1 2 0 0 2 2 2 0 Bacteriophage coat protein B APH PF01636.23 RLN88990.1 - 0.044 13.7 0.2 0.44 10.4 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN88990.1 - 0.082 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain LRR_4 PF12799.7 RLN88990.1 - 0.14 12.6 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) Tachystatin_B PF11478.8 RLN88990.1 - 0.36 10.8 2.1 0.82 9.7 2.1 1.5 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B DUF883 PF05957.13 RLN88993.1 - 0.72 10.5 7.8 1.8 9.2 3.2 2.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF4381 PF14316.6 RLN88993.1 - 1 9.6 3.9 0.22 11.8 0.9 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) YtxH PF12732.7 RLN88993.1 - 3.5 8.2 5.2 0.91 10.1 2.0 1.6 2 0 0 2 2 2 0 YtxH-like protein Pkinase PF00069.25 RLN88994.1 - 5.8e-72 242.2 0.0 7.5e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN88994.1 - 2.3e-45 154.9 0.0 3e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN88994.1 - 3e-05 23.5 0.0 0.00029 20.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 RLN88994.1 - 0.058 13.0 0.2 0.14 11.7 0.2 1.6 1 1 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 RLN88994.1 - 0.091 12.3 0.3 0.28 10.7 0.3 1.8 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Nucleoside_tran PF01733.18 RLN88995.1 - 1.8e-21 76.8 9.2 4.9e-17 62.3 0.2 2.7 2 1 1 3 3 3 2 Nucleoside transporter EF-hand_8 PF13833.6 RLN88996.1 - 6.9e-10 38.6 0.0 9.6e-06 25.4 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 RLN88996.1 - 1.1e-08 35.4 2.3 0.00051 20.4 0.1 3.6 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN88996.1 - 1.9e-08 33.3 0.6 6.2e-05 22.3 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RLN88996.1 - 5.4e-07 29.0 1.3 0.0035 17.1 0.1 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 RLN88996.1 - 6.1e-06 25.5 0.7 0.00042 19.7 0.0 3.2 3 0 0 3 3 3 1 EF hand Cul7 PF11515.8 RLN88998.1 - 0.051 13.9 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Mouse development and cellular proliferation protein Cullin-7 Ribonuc_L-PSP PF01042.21 RLN88999.1 - 0.011 15.8 0.0 0.042 13.9 0.0 2.0 1 0 0 1 1 1 0 Endoribonuclease L-PSP FA_FANCE PF11510.8 RLN89000.1 - 1.4e-09 37.7 1.5 5.6e-09 35.7 1.5 1.8 1 1 0 1 1 1 1 Fanconi Anaemia group E protein FANCE Xpo1 PF08389.12 RLN89000.1 - 0.037 14.1 0.3 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Exportin 1-like protein Cyt-b5 PF00173.28 RLN89001.1 - 1.8e-09 37.6 0.0 4.3e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TP6A_N PF04406.14 RLN89001.1 - 0.092 12.7 0.2 0.38 10.8 0.2 2.0 1 0 0 1 1 1 0 Type IIB DNA topoisomerase Syntaxin-6_N PF09177.11 RLN89002.1 - 0.018 15.6 0.2 0.023 15.2 0.2 1.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal FmiP_Thoc5 PF09766.9 RLN89002.1 - 0.02 14.2 1.5 0.025 13.9 1.5 1.0 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 Phage_Mu_Gam PF07352.12 RLN89002.1 - 0.039 13.9 1.7 0.052 13.5 1.7 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein TPD52 PF04201.15 RLN89002.1 - 0.053 13.1 0.2 0.064 12.9 0.2 1.2 1 0 0 1 1 1 0 Tumour protein D52 family KMP11 PF03037.16 RLN89002.1 - 0.1 13.4 0.0 0.14 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 Torus PF16131.5 RLN89003.1 - 1.2e-07 32.4 6.7 9e-06 26.3 0.6 2.4 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 RLN89003.1 - 1.2e-05 25.5 3.1 5.4e-05 23.4 3.2 1.9 1 1 1 2 2 2 2 Zinc-finger containing family zf_CCCH_4 PF18345.1 RLN89003.1 - 0.00092 19.2 9.7 0.0048 16.9 1.4 3.1 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH PF00642.24 RLN89003.1 - 0.0027 17.6 5.6 0.54 10.2 0.7 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) VP4_helical PF17478.2 RLN89003.1 - 0.22 10.9 2.1 0.28 10.6 2.1 1.1 1 0 0 1 1 1 0 Rotavirus VP4 helical domain DUF4789 PF16033.5 RLN89003.1 - 0.22 12.1 2.9 0.38 11.3 2.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4789) zf-CCCH_2 PF14608.6 RLN89003.1 - 1.5 9.4 5.5 0.94 10.1 0.8 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Evr1_Alr PF04777.13 RLN89004.1 - 1.6e-19 70.2 0.5 3.5e-19 69.1 0.5 1.5 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.20 RLN89004.1 - 5.7e-18 64.8 0.1 1e-17 64.0 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 RLN89004.1 - 0.011 15.1 0.0 0.061 12.7 0.0 2.0 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 RLN89004.1 - 0.087 13.2 0.1 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like eIF-5_eIF-2B PF01873.17 RLN89004.1 - 0.17 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain found in IF2B/IF5 DUF4234 PF14018.6 RLN89004.1 - 0.35 11.0 2.3 29 4.9 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) BK_channel_a PF03493.18 RLN89005.1 - 1.5e-19 70.0 0.0 5.4e-18 65.0 0.0 2.7 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit TrkA_N PF02254.18 RLN89005.1 - 1.5e-08 34.9 0.0 0.00039 20.7 0.0 2.5 2 0 0 2 2 2 2 TrkA-N domain Ion_trans_2 PF07885.16 RLN89005.1 - 0.014 15.3 1.4 0.06 13.3 1.4 2.1 1 0 0 1 1 1 0 Ion channel Dynactin PF12455.8 RLN89005.1 - 0.26 10.5 0.2 0.41 9.9 0.2 1.2 1 0 0 1 1 1 0 Dynein associated protein Cupin_8 PF13621.6 RLN89006.1 - 1.8e-14 54.1 2.5 7.4e-11 42.2 0.6 2.3 1 1 1 2 2 2 2 Cupin-like domain JmjC PF02373.22 RLN89006.1 - 1.1e-08 35.5 0.3 3.5e-08 33.9 0.1 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 RLN89006.1 - 0.0072 15.8 0.3 0.12 11.8 0.0 2.3 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.11 RLN89006.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Cupin domain PspB PF06667.12 RLN89006.1 - 1.5 9.0 4.0 0.95 9.6 1.1 2.2 2 1 0 2 2 2 0 Phage shock protein B Spc7 PF08317.11 RLN89007.1 - 0.0062 15.4 24.0 0.0062 15.4 24.0 5.5 2 2 4 6 6 6 3 Spc7 kinetochore protein DASH_Dam1 PF08653.10 RLN89007.1 - 0.15 11.8 8.7 3.6 7.4 0.1 5.9 6 1 1 7 7 7 0 DASH complex subunit Dam1 OAR PF03826.17 RLN89007.1 - 0.94 9.4 4.4 0.53 10.2 0.4 2.6 2 0 0 2 2 2 0 OAR domain Baculo_PEP_C PF04513.12 RLN89007.1 - 0.98 9.5 23.1 1.3 9.0 5.6 5.2 2 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glyco_hydro_1 PF00232.18 RLN89008.1 - 1.1e-108 363.5 0.3 1.8e-108 362.9 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Metallophos PF00149.28 RLN89008.1 - 7.8e-15 55.9 0.1 6.5e-14 52.9 0.0 2.5 4 0 0 4 4 4 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 RLN89008.1 - 9.8e-07 29.3 0.1 3.4e-06 27.5 0.1 2.0 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Cellulase PF00150.18 RLN89008.1 - 0.034 13.6 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Xylo_C PF12529.8 RLN89009.1 - 0.041 13.5 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 Xylosyltransferase C terminal DUF4174 PF13778.6 RLN89009.1 - 0.12 12.9 0.0 0.67 10.4 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4174) FYVE PF01363.21 RLN89010.1 - 7e-15 54.9 11.9 1.1e-14 54.3 11.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN89010.1 - 0.0033 17.6 8.0 0.0056 16.9 8.0 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger zf-RING_UBOX PF13445.6 RLN89010.1 - 0.14 12.2 3.9 0.31 11.1 4.0 1.6 1 1 0 1 1 1 0 RING-type zinc-finger C1_2 PF03107.16 RLN89010.1 - 0.86 10.0 9.4 0.42 11.0 6.1 2.0 2 0 0 2 2 2 0 C1 domain zf-RING_2 PF13639.6 RLN89010.1 - 0.88 10.0 10.5 1.9 8.9 10.5 1.6 1 1 0 1 1 1 0 Ring finger domain DZR PF12773.7 RLN89010.1 - 5.8 7.0 10.6 2.2e+02 1.9 2.4 2.4 1 1 1 2 2 2 0 Double zinc ribbon TFR_dimer PF04253.15 RLN89011.1 - 5.2e-21 75.0 0.0 3.4e-20 72.4 0.0 2.1 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 RLN89011.1 - 7.5e-09 35.6 0.0 1.4e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 RLN89011.1 - 0.02 14.9 0.0 0.061 13.3 0.0 1.9 1 0 0 1 1 1 0 PA domain Phage_tail_X PF05489.12 RLN89011.1 - 0.03 14.0 0.1 0.062 13.0 0.1 1.5 1 0 0 1 1 1 0 Phage Tail Protein X Nicastrin PF05450.15 RLN89011.1 - 0.14 11.6 0.0 0.38 10.2 0.0 1.6 2 0 0 2 2 2 0 Nicastrin RyR PF02026.16 RLN89012.1 - 5.7e-61 202.7 0.2 1.4e-30 105.4 0.0 2.9 3 0 0 3 3 3 2 RyR domain PKD_channel PF08016.12 RLN89012.1 - 5.4e-37 127.5 12.3 1.7e-29 102.8 13.2 2.2 2 0 0 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 RLN89012.1 - 1.5e-11 44.0 14.5 2.2e-11 43.5 14.5 1.2 1 0 0 1 1 1 1 Ion transport protein PI3_PI4_kinase PF00454.27 RLN89013.1 - 3.1e-31 109.1 0.0 4.6e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Helicase_C_3 PF13625.6 RLN89013.1 - 0.06 13.5 0.5 1.9 8.7 0.0 2.7 3 0 0 3 3 3 0 Helicase conserved C-terminal domain SRP40_C PF05022.12 RLN89014.1 - 1.7e-22 80.1 0.6 1.7e-22 80.1 0.6 2.6 2 0 0 2 2 2 1 SRP40, C-terminal domain LisH PF08513.11 RLN89014.1 - 0.012 15.5 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 LisH CAP PF00188.26 RLN89016.1 - 8.4e-05 23.4 0.0 0.00013 22.8 0.0 1.4 1 1 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 RLN89017.1 - 5.6e-12 46.6 2.0 5.6e-12 46.6 2.0 2.4 2 1 0 2 2 2 1 Cysteine-rich secretory protein family PMP1_2 PF08114.11 RLN89017.1 - 0.024 14.4 0.1 0.043 13.6 0.1 1.4 1 0 0 1 1 1 0 ATPase proteolipid family LAP1C PF05609.12 RLN89017.1 - 3.7 6.5 19.3 5.2 6.1 19.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 RLN89017.1 - 7.9 4.9 24.8 14 4.1 24.8 1.4 1 0 0 1 1 1 0 Macoilin family TPR_1 PF00515.28 RLN89018.1 - 5.5e-13 48.1 6.2 8e-05 22.3 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN89018.1 - 1.1e-11 43.9 8.2 0.0036 17.3 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN89018.1 - 4.5e-07 29.4 6.4 0.00021 20.9 0.9 2.7 2 1 0 2 2 2 2 TPR repeat TPR_17 PF13431.6 RLN89018.1 - 0.00011 22.3 0.8 0.0026 18.0 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN89018.1 - 0.00064 20.3 12.3 0.00075 20.1 1.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN89018.1 - 0.0013 19.2 2.1 0.0013 19.2 2.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN89018.1 - 0.0018 18.3 2.3 0.18 12.1 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat CHASE7 PF17151.4 RLN89018.1 - 0.0042 16.7 0.2 0.0082 15.8 0.2 1.4 1 0 0 1 1 1 1 Periplasmic sensor domain ANAPC3 PF12895.7 RLN89018.1 - 0.0097 16.1 4.2 0.056 13.7 0.2 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 RLN89018.1 - 0.011 15.9 1.0 0.011 15.9 1.0 4.2 3 2 2 5 5 5 0 Tetratricopeptide repeat phage_tail_N PF08400.10 RLN89018.1 - 0.074 13.0 0.2 0.19 11.7 0.2 1.7 1 0 0 1 1 1 0 Prophage tail fibre N-terminal TPR_14 PF13428.6 RLN89018.1 - 0.11 13.4 8.9 0.31 12.0 0.7 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat CCDC53 PF10152.9 RLN89018.1 - 0.15 12.5 1.3 0.26 11.7 1.3 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex POPLD PF08170.12 RLN89018.1 - 1.4 9.3 3.6 20 5.6 1.8 2.5 2 1 0 2 2 2 0 POPLD (NUC188) domain Adaptin_N PF01602.20 RLN89019.1 - 2.2e-57 194.8 1.0 2.8e-57 194.5 1.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region AP3B1_C PF14796.6 RLN89019.1 - 2.4e-16 60.3 0.0 4.7e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal HEAT_2 PF13646.6 RLN89019.1 - 1.6e-06 28.4 0.5 0.00043 20.6 0.0 3.0 1 1 2 3 3 3 1 HEAT repeats SPO22 PF08631.10 RLN89019.1 - 0.035 13.6 0.3 0.035 13.6 0.3 1.7 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like Sec7_N PF12783.7 RLN89019.1 - 0.2 11.6 0.5 0.55 10.1 0.5 1.8 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Macoilin PF09726.9 RLN89019.1 - 0.23 10.0 12.5 0.31 9.5 12.5 1.1 1 0 0 1 1 1 0 Macoilin family SDA1 PF05285.12 RLN89019.1 - 0.56 9.6 22.5 0.85 9.0 22.5 1.1 1 0 0 1 1 1 0 SDA1 SR-25 PF10500.9 RLN89019.1 - 8.1 6.0 37.6 15 5.1 37.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SOBP PF15279.6 RLN89019.1 - 9.1 6.8 7.1 15 6.1 7.1 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein FAA_hydrolase PF01557.18 RLN89021.1 - 1.5e-49 168.6 0.0 2.2e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 RLN89021.1 - 1.6e-09 37.9 0.3 2.9e-09 37.0 0.3 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal FAA_hydrolase_N PF09298.11 RLN89022.1 - 1.4e-09 38.1 0.0 2.5e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal zf-BED PF02892.15 RLN89023.1 - 0.0021 18.1 7.8 0.15 12.1 0.3 3.9 3 1 0 3 3 3 2 BED zinc finger F-box_4 PF15966.5 RLN89023.1 - 0.11 12.4 0.2 4.4 7.2 0.0 3.1 3 0 0 3 3 3 0 F-box zf_C2HC_14 PF18574.1 RLN89023.1 - 1.4 8.8 6.4 0.67 9.8 0.4 3.3 3 0 0 3 3 3 0 C2HC Zing finger domain zf-U11-48K PF05253.12 RLN89023.1 - 2.5 8.1 7.5 2 8.4 0.1 3.1 3 0 0 3 3 3 0 U11-48K-like CHHC zinc finger zf-HC2 PF13490.6 RLN89023.1 - 4.3 7.7 8.9 32 4.9 0.0 4.8 5 0 0 5 5 5 0 Putative zinc-finger Ank_2 PF12796.7 RLN89026.1 - 2.6e-33 114.4 16.9 1.8e-12 47.6 1.5 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN89026.1 - 5e-23 80.9 10.9 3.2e-08 33.7 0.2 6.0 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN89026.1 - 1.6e-19 67.9 12.0 0.0001 22.4 0.3 6.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 RLN89026.1 - 1.6e-18 66.8 10.2 3.7e-08 33.7 1.4 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN89026.1 - 1.7e-17 63.0 17.7 0.00042 20.6 0.2 6.1 6 0 0 6 6 6 4 Ankyrin repeat PA PF02225.22 RLN89026.1 - 1.9e-17 63.1 0.4 4.1e-08 33.1 0.1 2.8 2 0 0 2 2 2 2 PA domain TPR_2 PF07719.17 RLN89026.1 - 0.019 15.1 0.2 0.074 13.2 0.2 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3992 PF13157.6 RLN89026.1 - 0.031 15.0 0.0 1.4 9.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3992) TMF_TATA_bd PF12325.8 RLN89026.1 - 0.64 10.3 6.5 1.7 8.9 6.5 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Peptidase_C12 PF01088.21 RLN89027.1 - 2.4e-26 92.8 0.0 8.6e-26 91.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 PNP_UDP_1 PF01048.20 RLN89027.1 - 1.7e-16 60.2 0.3 9.1e-16 57.8 0.1 2.2 2 1 0 2 2 2 1 Phosphorylase superfamily PH PF00169.29 RLN89028.1 - 1.2e-35 122.2 1.6 2.4e-15 56.9 0.1 3.9 3 0 0 3 3 3 3 PH domain PH_8 PF15409.6 RLN89028.1 - 2e-08 34.4 5.1 0.00022 21.5 0.3 3.1 3 0 0 3 3 3 2 Pleckstrin homology domain PH_11 PF15413.6 RLN89028.1 - 1.7e-07 31.6 15.2 0.00063 20.1 2.8 4.4 3 3 1 4 4 4 2 Pleckstrin homology domain PH_3 PF14593.6 RLN89028.1 - 9.4e-07 28.9 0.1 0.012 15.7 0.0 3.2 1 1 2 3 3 3 2 PH domain zf-ribbon_3 PF13248.6 RLN89028.1 - 0.00026 20.3 1.9 0.00051 19.4 1.9 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 RLN89028.1 - 0.016 15.2 0.6 0.035 14.1 0.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon Arb2 PF09757.9 RLN89028.1 - 0.15 11.2 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Arb2 domain zinc_ribbon_2 PF13240.6 RLN89028.1 - 0.16 11.7 4.2 0.33 10.7 4.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 RLN89028.1 - 0.17 12.6 0.3 0.38 11.5 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon family CDC45 PF02724.14 RLN89028.1 - 2.5 6.3 7.1 5.7 5.1 7.1 1.5 1 0 0 1 1 1 0 CDC45-like protein PH_9 PF15410.6 RLN89028.1 - 8.5 6.8 7.2 71 3.8 0.1 4.3 4 2 1 5 5 5 0 Pleckstrin homology domain Beta_helix PF13229.6 RLN89029.1 - 3.2e-05 23.9 4.3 9.9e-05 22.2 4.3 1.7 1 1 0 1 1 1 1 Right handed beta helix region CDC37_N PF03234.14 RLN89030.1 - 0.22 12.5 1.8 0.35 11.8 1.0 1.7 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Str_synth PF03088.16 RLN89031.1 - 4e-16 58.9 0.0 1.1e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 Strictosidine synthase SGL PF08450.12 RLN89031.1 - 5e-11 42.7 0.0 3.6e-10 39.9 0.0 2.2 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 RLN89031.1 - 0.0007 19.5 1.4 1.6 8.9 0.0 4.2 4 0 0 4 4 4 2 NHL repeat Arylesterase PF01731.20 RLN89031.1 - 0.001 19.3 0.0 0.0074 16.5 0.0 2.3 1 1 1 2 2 2 1 Arylesterase Glu_cyclase_2 PF05096.12 RLN89031.1 - 0.2 11.1 0.0 0.52 9.7 0.0 1.8 2 0 0 2 2 2 0 Glutamine cyclotransferase PQQ_3 PF13570.6 RLN89031.1 - 1.5 9.4 3.9 14 6.3 0.9 3.4 3 1 0 3 3 3 0 PQQ-like domain PH PF00169.29 RLN89033.1 - 7.2e-05 23.3 0.1 0.00045 20.7 0.0 2.1 2 0 0 2 2 2 1 PH domain IQ PF00612.27 RLN89033.1 - 0.045 13.6 0.3 0.11 12.4 0.3 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif PhoD PF09423.10 RLN89035.1 - 1.5e-11 43.9 1.0 2.9e-11 43.0 1.0 1.4 1 1 0 1 1 1 1 PhoD-like phosphatase Phage_int_SAM_1 PF02899.17 RLN89035.1 - 0.15 12.4 2.9 0.3 11.4 0.1 2.3 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain zf-RanBP PF00641.18 RLN89036.1 - 0.058 12.7 6.9 0.1 11.9 6.9 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others PPR_2 PF13041.6 RLN89037.1 - 0.00033 20.8 0.0 0.54 10.5 0.0 3.5 3 0 0 3 3 3 2 PPR repeat family HTH_DeoR PF08220.12 RLN89037.1 - 0.11 12.2 0.1 0.33 10.7 0.1 1.8 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain zinc-ribbon_6 PF10005.9 RLN89038.1 - 0.00081 20.0 0.7 0.0014 19.3 0.7 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 RLN89038.1 - 0.0072 16.3 0.3 0.014 15.4 0.3 1.7 1 1 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 RLN89038.1 - 0.0085 16.8 0.1 0.017 15.9 0.1 1.5 1 0 0 1 1 1 1 zinc-ribbon family Auto_anti-p27 PF06677.12 RLN89038.1 - 0.022 14.9 1.4 0.045 13.9 1.4 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-NADH-PPase PF09297.11 RLN89038.1 - 0.036 13.7 1.1 0.13 11.9 0.0 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 RLN89038.1 - 0.044 13.5 1.9 0.85 9.4 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Arm PF00514.23 RLN89039.1 - 1.1e-54 180.9 14.1 2.3e-06 27.4 0.1 11.0 11 1 0 11 11 11 9 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 RLN89039.1 - 6.2e-09 35.8 3.9 0.77 9.8 0.0 7.0 2 2 4 8 8 8 3 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 RLN89039.1 - 1.8e-08 34.7 23.5 0.00034 20.9 0.4 6.0 1 1 6 7 7 7 5 HEAT repeats HEAT_EZ PF13513.6 RLN89039.1 - 1e-07 32.3 23.7 0.00025 21.5 0.3 7.9 7 3 2 9 9 9 3 HEAT-like repeat HEAT_PBS PF03130.16 RLN89039.1 - 8.8e-07 29.0 34.0 1.2 10.1 0.3 11.5 12 0 0 12 12 12 3 PBS lyase HEAT-like repeat UNC45-central PF11701.8 RLN89039.1 - 4.2e-05 23.6 0.1 3.8 7.5 0.0 4.1 4 1 1 5 5 5 3 Myosin-binding striated muscle assembly central HEAT PF02985.22 RLN89039.1 - 0.00079 19.5 9.7 15 6.1 0.0 8.4 10 0 0 10 10 10 1 HEAT repeat Op_neuropeptide PF08035.11 RLN89039.1 - 0.025 14.4 1.3 81 3.2 0.0 4.5 5 0 0 5 5 5 0 Opioids neuropeptide Glyco_hydro38C2 PF17677.1 RLN89042.1 - 0.061 13.4 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain GAF PF01590.26 RLN89043.1 - 3.4e-07 31.0 0.1 1.8e-06 28.6 0.1 2.4 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 RLN89043.1 - 6.5e-05 23.3 0.3 0.0021 18.4 0.0 3.2 3 0 0 3 3 3 1 GAF domain DsbG_N PF18257.1 RLN89044.1 - 0.069 13.3 0.1 0.34 11.1 0.1 2.1 2 0 0 2 2 2 0 Disulfide isomerase DsbG N-terminal Pkinase_Tyr PF07714.17 RLN89045.1 - 6.1e-09 35.5 0.0 0.0028 17.0 0.0 3.3 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 RLN89045.1 - 2.5e-06 27.1 0.0 0.042 13.2 0.0 2.6 1 1 1 2 2 2 2 Protein kinase domain Xpo1 PF08389.12 RLN89046.1 - 2.6e-09 37.3 0.4 4e-05 23.7 0.0 3.3 4 0 0 4 4 4 2 Exportin 1-like protein Guanylate_cyc PF00211.20 RLN89047.1 - 1.4e-11 44.4 0.0 3e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Glyco_hydro_17 PF00332.18 RLN89048.1 - 2.9e-06 27.1 1.5 0.00024 20.8 0.3 2.9 2 1 1 3 3 3 2 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.13 RLN89048.1 - 0.0031 16.6 0.1 0.009 15.0 0.2 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 53 Glyco_hydro_17 PF00332.18 RLN89049.1 - 4e-06 26.6 1.4 0.00028 20.6 0.2 2.8 2 1 1 3 3 3 2 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.13 RLN89049.1 - 0.0033 16.5 0.2 0.0079 15.2 0.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 53 RuvX PF03652.15 RLN89050.1 - 0.019 15.3 0.0 0.031 14.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction resolvase OrfB_Zn_ribbon PF07282.11 RLN89050.1 - 0.36 10.8 7.3 1.8 8.5 1.9 2.9 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Guanylate_cyc PF00211.20 RLN89051.1 - 3.4e-12 46.4 0.0 6.6e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain NAD_Gly3P_dh_N PF01210.23 RLN89052.1 - 1e-18 67.8 0.0 1.1e-18 67.7 0.0 1.0 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AcetDehyd-dimer PF09290.11 RLN89052.1 - 0.12 12.6 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation PIF1 PF05970.14 RLN89053.1 - 0.0042 16.3 0.2 0.012 14.8 0.2 1.9 1 1 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.6 RLN89053.1 - 0.0045 16.8 1.4 0.066 13.0 1.4 2.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain PE-PPE PF08237.11 RLN89053.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain CENP-B_dimeris PF09026.10 RLN89055.1 - 0.022 15.2 13.3 0.027 14.8 13.3 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 RLN89055.1 - 0.19 9.9 5.9 0.18 10.0 5.9 1.0 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 RLN89055.1 - 0.3 10.7 2.5 0.3 10.8 2.5 1.2 1 0 0 1 1 1 0 FAM176 family BUD22 PF09073.10 RLN89055.1 - 0.37 10.1 12.1 0.39 10.0 12.1 1.0 1 0 0 1 1 1 0 BUD22 TRAP_alpha PF03896.16 RLN89055.1 - 1.7 7.8 4.2 1.7 7.8 4.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 RLN89055.1 - 2.1 7.6 9.9 2.4 7.4 9.9 1.1 1 0 0 1 1 1 0 NOA36 protein Astro_capsid_p PF12226.8 RLN89055.1 - 2.5 7.2 9.8 2.9 7.0 9.8 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein EBV-NA3 PF05009.12 RLN89055.1 - 2.5 7.5 5.3 2.8 7.4 5.3 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) YL1 PF05764.13 RLN89055.1 - 3.8 7.5 12.0 4.4 7.4 12.0 1.0 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 RLN89055.1 - 4.1 5.6 7.8 4.1 5.6 7.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 RLN89055.1 - 6.5 4.7 12.2 7.2 4.6 12.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi zf-C3H1 PF10650.9 RLN89056.1 - 0.57 10.0 1.7 1.2 9.0 1.7 1.4 1 0 0 1 1 1 0 Putative zinc-finger domain Sulfate_transp PF00916.20 RLN89057.1 - 5.1e-39 134.1 12.2 7.1e-39 133.6 12.2 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 RLN89057.1 - 9.1e-14 51.3 0.0 1.6e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 RLN89057.1 - 2.6e-06 27.1 0.0 8e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 STAS domain Nop14 PF04147.12 RLN89058.1 - 0.034 12.4 0.1 0.039 12.2 0.1 1.0 1 0 0 1 1 1 0 Nop14-like family IBN_N PF03810.19 RLN89059.1 - 2.4e-09 37.0 1.4 1.7e-08 34.3 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 RLN89059.1 - 5.1e-08 32.1 1.5 1.8e-07 30.3 0.1 2.1 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.12 RLN89059.1 - 3.9e-06 27.0 5.7 0.00072 19.6 0.0 3.9 4 0 0 4 4 4 2 Exportin 1-like protein Importin_rep_4 PF18808.1 RLN89059.1 - 0.00011 22.4 1.7 0.0032 17.7 0.0 3.4 3 0 0 3 3 3 1 Importin repeat HEAT_EZ PF13513.6 RLN89059.1 - 0.016 15.7 19.2 0.098 13.2 0.7 6.6 6 0 0 6 6 6 0 HEAT-like repeat HEAT PF02985.22 RLN89059.1 - 0.66 10.4 5.5 8.5 6.9 0.0 5.5 7 0 0 7 7 7 0 HEAT repeat 5_nucleotid_C PF02872.18 RLN89063.1 - 1e-21 77.8 0.0 1.7e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 RLN89063.1 - 8.2e-10 39.5 0.0 1.2e-09 39.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ATP-gua_Ptrans PF00217.19 RLN89064.1 - 4.2e-71 238.8 0.0 4.8e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain Snf7 PF03357.21 RLN89065.1 - 3.7e-07 29.9 8.5 4.9e-07 29.5 8.5 1.2 1 0 0 1 1 1 1 Snf7 GLE1 PF07817.13 RLN89065.1 - 0.0028 16.9 2.3 0.0033 16.7 2.3 1.0 1 0 0 1 1 1 1 GLE1-like protein YlqD PF11068.8 RLN89065.1 - 0.0038 17.6 5.9 0.0045 17.4 5.9 1.2 1 0 0 1 1 1 1 YlqD protein HTH_36 PF13730.6 RLN89065.1 - 0.022 14.7 0.1 4.1 7.4 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain z-alpha PF02295.17 RLN89065.1 - 0.15 12.1 3.0 0.15 12.1 1.6 1.7 1 1 1 2 2 2 0 Adenosine deaminase z-alpha domain NAM-associated PF14303.6 RLN89065.1 - 0.23 12.2 7.9 0.27 11.9 7.9 1.0 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain PKD_channel PF08016.12 RLN89068.1 - 3.7e-32 111.5 19.4 3.2e-22 78.8 14.7 3.2 2 1 1 3 3 3 3 Polycystin cation channel Ion_trans PF00520.31 RLN89068.1 - 2.6e-09 36.7 17.2 2.6e-09 36.7 17.2 2.6 2 1 0 2 2 2 1 Ion transport protein RRM_1 PF00076.22 RLN89069.1 - 9.4e-34 115.1 0.0 9.6e-11 41.4 0.0 4.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 RLN89069.1 - 1.1e-24 86.2 6.1 0.00036 21.3 0.0 7.9 7 1 1 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN89069.1 - 5e-10 39.5 0.0 0.083 13.2 0.0 5.8 3 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 RLN89069.1 - 0.11 11.8 0.0 1.3 8.2 0.0 2.6 4 0 0 4 4 4 0 CPSF A subunit region HPS3_N PF14761.6 RLN89069.1 - 0.13 11.8 0.2 30 4.0 0.0 3.5 4 0 0 4 4 4 0 Hermansky-Pudlak syndrome 3 RRM_5 PF13893.6 RLN89069.1 - 0.17 11.5 0.1 36 4.0 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIID-31kDa PF02291.15 RLN89070.1 - 1.7e-09 37.8 0.0 2e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Arginase PF00491.21 RLN89071.1 - 4.2e-63 213.5 0.0 5.2e-63 213.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family Cyt-b5 PF00173.28 RLN89072.1 - 7.9e-12 45.2 0.0 1.8e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BTB PF00651.31 RLN89072.1 - 0.035 14.3 0.0 0.075 13.3 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain TRM13 PF05206.14 RLN89073.1 - 2.4e-53 181.3 0.0 4.9e-53 180.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 RLN89073.1 - 1.2e-10 41.0 1.5 1.2e-10 41.0 1.5 2.2 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 RLN89073.1 - 9.6e-08 31.8 0.0 2e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.6 RLN89073.1 - 0.036 14.0 0.1 0.24 11.4 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 RLN89073.1 - 0.064 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase TT_ORF2 PF02957.15 RLN89073.1 - 0.095 13.6 4.7 2 9.4 0.0 2.9 3 0 0 3 3 3 0 TT viral ORF2 Methyltransf_31 PF13847.6 RLN89073.1 - 0.12 12.2 0.0 0.45 10.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 RLN89073.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain UPF0029 PF01205.19 RLN89074.1 - 7.6e-32 109.8 0.0 1.1e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Dynein_attach_N PF15867.5 RLN89075.1 - 2.3e-11 43.4 1.6 4.4e-11 42.6 1.6 1.4 1 0 0 1 1 1 1 Dynein attachment factor N-terminus RPAP3_C PF13877.6 RLN89075.1 - 2.2e-08 34.5 0.7 5.2e-08 33.3 0.7 1.7 1 1 0 1 1 1 1 Potential Monad-binding region of RPAP3 LysE PF01810.18 RLN89076.1 - 6.6e-10 38.8 10.4 8.8e-10 38.4 7.5 2.4 2 1 1 3 3 3 1 LysE type translocator Mito_carr PF00153.27 RLN89077.1 - 1.2e-57 191.8 3.6 1.7e-23 82.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein KIAA1430 PF13879.6 RLN89078.1 - 3e-28 98.6 15.2 6.4e-28 97.5 15.2 1.6 1 0 0 1 1 1 1 KIAA1430 homologue TMCO5 PF14992.6 RLN89078.1 - 0.039 13.5 0.3 0.039 13.5 0.3 2.2 1 1 1 2 2 2 0 TMCO5 family Ank_2 PF12796.7 RLN89079.1 - 9.7e-42 141.5 19.0 2.1e-18 66.7 3.3 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN89079.1 - 4.1e-27 94.2 5.5 4.2e-13 49.5 0.9 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) FH2 PF02181.23 RLN89079.1 - 4.2e-23 82.1 0.0 1.5e-16 60.5 0.0 2.2 2 0 0 2 2 2 2 Formin Homology 2 Domain Ank_3 PF13606.6 RLN89079.1 - 9.9e-20 68.6 6.6 0.0004 20.6 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 RLN89079.1 - 2.6e-19 68.7 12.2 0.00039 20.7 0.1 6.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 RLN89079.1 - 8.8e-13 48.2 8.2 2.3e-05 24.6 0.6 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) C2 PF00168.30 RLN89079.1 - 1.3e-05 25.4 0.0 2.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain PH_12 PF16457.5 RLN89079.1 - 0.00021 21.8 0.1 0.001 19.6 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 RLN89079.1 - 0.00055 20.4 0.0 0.0019 18.7 0.0 1.9 1 0 0 1 1 1 1 PH domain Mcp5_PH PF12814.7 RLN89079.1 - 0.0041 17.2 0.0 0.0096 16.0 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH_2 PF08458.10 RLN89079.1 - 0.036 14.4 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 Plant pleckstrin homology-like region DUF5423 PF17461.2 RLN89079.1 - 0.71 8.7 3.4 0.24 10.2 0.2 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5423) Kinesin PF00225.23 RLN89080.1 - 5.3e-62 209.7 0.1 4.1e-34 118.0 0.0 2.0 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 RLN89080.1 - 1.2e-14 54.5 0.0 2.1e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Mito_carr PF00153.27 RLN89081.1 - 1e-67 224.1 2.1 6.7e-23 80.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 RLN89081.1 - 0.018 14.2 2.3 0.048 12.8 0.1 2.7 4 1 0 4 4 4 0 Gammaproteobacterial serine protease MeaB PF03308.16 RLN89083.1 - 2.5e-51 174.2 1.9 3.5e-51 173.8 1.9 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 RLN89083.1 - 4e-07 29.8 0.2 0.011 15.3 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 RLN89083.1 - 0.0018 18.0 0.3 0.003 17.3 0.3 1.3 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 RLN89083.1 - 0.0024 17.7 0.1 0.0057 16.5 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 RLN89083.1 - 0.0059 17.1 0.0 0.01 16.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 RLN89083.1 - 0.0081 15.9 0.1 0.018 14.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 RLN89083.1 - 0.015 15.3 0.0 0.092 12.8 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase Mg_chelatase PF01078.21 RLN89083.1 - 0.02 14.3 0.1 0.35 10.2 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 RLN89083.1 - 0.021 14.5 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 RLN89083.1 - 0.038 13.7 0.2 0.22 11.2 0.1 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.15 RLN89083.1 - 0.053 13.4 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 NTPase PRK PF00485.18 RLN89083.1 - 0.06 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 RLN89083.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 RLN89083.1 - 0.092 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RLN89083.1 - 0.098 13.0 0.0 0.23 11.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 RLN89083.1 - 0.12 13.0 0.3 0.27 11.8 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 RLN89083.1 - 0.19 11.9 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 RLN89083.1 - 0.27 11.7 0.1 0.47 10.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain PDZ_6 PF17820.1 RLN89084.1 - 3.3e-05 23.6 0.0 8.8e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RLN89084.1 - 0.08 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 PDZ domain NAD_binding_1 PF00175.21 RLN89085.1 - 2.3e-09 37.9 0.0 1.3e-08 35.5 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 RLN89085.1 - 7.9e-09 35.8 0.0 1.3e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.22 RLN89085.1 - 4.3e-08 33.7 0.0 6.9e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Globin NAD_binding_6 PF08030.12 RLN89085.1 - 0.0025 17.9 0.0 0.012 15.8 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain GSHPx PF00255.19 RLN89085.1 - 0.12 11.9 0.0 0.38 10.3 0.0 1.8 2 0 0 2 2 2 0 Glutathione peroxidase Pkinase PF00069.25 RLN89086.1 - 1.5e-41 142.5 7.6 6.5e-21 74.9 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89086.1 - 1.7e-11 43.9 0.4 5e-06 26.0 0.3 2.7 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 RLN89086.1 - 0.065 13.1 9.4 2.2 8.2 0.0 4.1 3 1 0 3 3 3 0 Phosphotransferase enzyme family DUF3584 PF12128.8 RLN89087.1 - 0.39 8.2 10.4 0.047 11.2 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 RLN89087.1 - 8.5 5.6 10.7 1.7 7.9 4.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SecE PF00584.20 RLN89090.1 - 0.65 10.0 2.5 1.3 9.0 2.5 1.4 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex DUF5446 PF17522.2 RLN89091.1 - 0.11 12.6 3.7 0.17 12.1 0.7 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5446) Spc29 PF17082.5 RLN89091.1 - 0.77 9.5 6.4 0.4 10.5 3.6 1.8 1 1 0 1 1 1 0 Spindle Pole Component 29 DUF724 PF05266.14 RLN89091.1 - 1.3 8.9 18.7 1 9.1 6.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Glyco_hydro_31 PF01055.26 RLN89092.1 - 2e-151 505.1 1.1 2.8e-151 504.7 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 RLN89092.1 - 1.3e-28 99.5 0.6 3.1e-28 98.3 0.6 1.7 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 RLN89092.1 - 4.7e-08 33.2 0.1 2.1e-07 31.1 0.1 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like zf-HIT PF04438.16 RLN89092.1 - 1.1 9.2 5.7 1.8 8.5 5.7 1.4 1 0 0 1 1 1 0 HIT zinc finger CAP_GLY PF01302.25 RLN89093.1 - 2.6e-21 75.4 0.2 5.4e-21 74.4 0.2 1.5 1 0 0 1 1 1 1 CAP-Gly domain MPS2 PF17060.5 RLN89093.1 - 0.0097 15.2 1.4 0.016 14.5 1.4 1.3 1 0 0 1 1 1 1 Monopolar spindle protein 2 Macoilin PF09726.9 RLN89093.1 - 0.011 14.4 5.4 0.022 13.3 5.4 1.4 1 0 0 1 1 1 0 Macoilin family GAS PF13851.6 RLN89093.1 - 0.012 15.0 10.0 0.015 14.6 9.4 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.7 RLN89093.1 - 0.014 15.6 10.3 0.026 14.7 10.3 1.4 1 0 0 1 1 1 0 Tropomyosin like FAM76 PF16046.5 RLN89093.1 - 0.12 11.7 7.6 1.4 8.2 7.6 2.1 1 1 0 1 1 1 0 FAM76 protein PI3K_P85_iSH2 PF16454.5 RLN89093.1 - 0.22 11.1 6.3 0.58 9.7 6.3 1.7 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FUSC PF04632.12 RLN89093.1 - 0.31 9.5 11.3 0.44 9.0 11.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family WHEP-TRS PF00458.20 RLN89093.1 - 0.46 10.7 2.7 1.2 9.4 2.7 1.7 1 0 0 1 1 1 0 WHEP-TRS domain TMF_DNA_bd PF12329.8 RLN89093.1 - 0.49 10.4 9.1 3 7.9 0.3 2.6 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.8 RLN89093.1 - 0.68 10.2 9.7 0.26 11.5 2.6 2.6 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Csm1_N PF18504.1 RLN89093.1 - 0.8 10.1 7.7 2.7 8.4 1.9 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain FlaC_arch PF05377.11 RLN89093.1 - 1 9.8 2.9 7 7.1 0.3 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Lebercilin PF15619.6 RLN89093.1 - 1.5 8.4 14.6 2.5 7.7 14.6 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 RLN89093.1 - 1.8 7.3 10.2 4.4 6.1 10.2 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein FAM184 PF15665.5 RLN89093.1 - 2 8.1 14.3 4.2 7.1 14.3 1.4 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B PX PF00787.24 RLN89095.1 - 0.067 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 PX domain Ferlin_C PF16165.5 RLN89096.1 - 0.77 9.7 2.3 1.3 9.0 0.5 2.2 1 1 1 2 2 2 0 Ferlin C-terminus RR_TM4-6 PF06459.12 RLN89096.1 - 1.3 8.8 9.7 1.6 8.5 9.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4813 PF16072.5 RLN89096.1 - 8.4 6.0 13.9 11 5.6 13.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Ank_2 PF12796.7 RLN89097.1 - 6.8e-34 116.3 2.9 4.9e-07 30.2 1.1 7.5 2 1 8 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN89097.1 - 2.8e-31 107.5 9.1 2.5e-05 24.8 0.5 10.4 9 1 1 10 10 10 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN89097.1 - 8.7e-19 67.4 28.4 0.0079 16.5 0.2 13.4 8 4 7 15 15 15 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN89097.1 - 1.1e-17 62.3 10.8 15 6.5 0.2 14.7 14 2 2 16 16 16 3 Ankyrin repeat AbiEi_3_N PF17194.4 RLN89097.1 - 0.011 15.7 3.8 5.6 7.1 0.1 5.6 6 2 2 8 8 8 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain Ank PF00023.30 RLN89097.1 - 3 8.4 9.6 47 4.7 0.3 6.7 8 1 0 8 8 8 0 Ankyrin repeat ArfGap PF01412.18 RLN89100.1 - 4.1e-31 107.5 1.2 1.1e-30 106.1 1.2 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DENN PF02141.21 RLN89100.1 - 3.3e-25 89.1 2.1 2.1e-23 83.3 0.3 2.4 1 1 1 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.18 RLN89100.1 - 6.5e-12 46.0 0.3 2.1e-11 44.4 0.3 2.0 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 RLN89100.1 - 2.4e-11 43.4 4.6 7.6e-11 41.8 4.6 2.0 1 0 0 1 1 1 1 dDENN domain CiPC PF15800.5 RLN89100.1 - 0.35 10.6 7.3 0.87 9.2 0.9 2.5 2 0 0 2 2 2 0 Clock interacting protein circadian SPRY PF00622.28 RLN89101.1 - 0.081 13.0 0.1 0.35 11.0 0.1 2.0 1 1 0 2 2 2 0 SPRY domain SPRY PF00622.28 RLN89102.1 - 3.1e-11 43.4 0.7 3.1e-10 40.2 0.1 2.6 3 1 0 3 3 3 1 SPRY domain Ribosomal_60s PF00428.19 RLN89102.1 - 0.012 16.2 4.1 1.3 9.7 0.7 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein LRR_6 PF13516.6 RLN89103.1 - 1.9e-39 130.4 24.6 0.0017 18.3 0.0 15.7 15 0 0 15 15 15 9 Leucine Rich repeat LRR_4 PF12799.7 RLN89103.1 - 4e-15 55.7 11.1 0.07 13.6 0.0 10.5 9 3 1 11 11 11 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN89103.1 - 7.3e-10 38.0 0.8 13 6.8 0.0 10.1 12 1 0 12 12 12 1 Leucine Rich Repeat LRR_8 PF13855.6 RLN89103.1 - 3.3e-08 33.2 17.1 0.18 11.6 0.1 10.0 7 5 1 8 8 8 3 Leucine rich repeat LRR_2 PF07723.13 RLN89103.1 - 0.0024 18.5 3.5 27 5.6 0.0 4.8 4 0 0 4 4 4 0 Leucine Rich Repeat PseudoU_synth_1 PF01416.20 RLN89103.1 - 0.13 12.8 0.0 0.91 10.0 0.0 2.5 3 0 0 3 3 3 0 tRNA pseudouridine synthase MgtE_N PF03448.17 RLN89103.1 - 0.76 10.4 8.5 2.8 8.6 0.1 3.9 4 0 0 4 4 4 0 MgtE intracellular N domain Y_phosphatase2 PF03162.13 RLN89104.1 - 1.5e-14 53.9 0.2 2.7e-12 46.6 0.1 2.9 1 1 1 2 2 2 2 Tyrosine phosphatase family PFU PF09070.11 RLN89105.1 - 1.1e-06 28.8 0.2 0.00025 21.3 0.0 3.6 4 0 0 4 4 4 1 PFU (PLAA family ubiquitin binding) GA-like PF17573.2 RLN89105.1 - 0.048 13.6 0.0 1.7 8.6 0.0 2.6 2 0 0 2 2 2 0 GA-like domain TonB_C PF03544.14 RLN89105.1 - 0.082 13.4 1.1 0.52 10.8 0.0 2.7 2 0 0 2 2 2 0 Gram-negative bacterial TonB protein C-terminal Arylesterase PF01731.20 RLN89105.1 - 0.2 11.9 0.0 2.2 8.5 0.0 2.6 3 0 0 3 3 3 0 Arylesterase CEP19 PF14933.6 RLN89105.1 - 0.23 11.8 0.7 2 8.7 0.1 2.4 2 0 0 2 2 2 0 CEP19-like protein TMCO5 PF14992.6 RLN89106.1 - 1.3 8.5 7.4 0.18 11.3 1.4 2.6 2 1 0 2 2 2 0 TMCO5 family SBP_bac_6 PF13343.6 RLN89107.1 - 1.6e-15 57.2 0.6 5.3e-13 48.9 0.2 2.3 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 RLN89107.1 - 5e-12 46.2 3.8 8.6e-12 45.4 3.8 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 RLN89107.1 - 4.2e-08 33.5 4.9 1e-07 32.2 4.9 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 RLN89107.1 - 0.00017 21.4 0.0 0.00042 20.1 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 RLN89108.1 - 5.6e-15 55.4 0.5 5.7e-11 42.3 0.1 2.2 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 RLN89108.1 - 6.9e-10 39.2 4.0 3.7e-09 36.8 4.0 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 RLN89108.1 - 2.2e-07 31.1 1.6 2.5e-05 24.4 1.6 2.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 RLN89108.1 - 0.0029 17.4 0.3 0.0054 16.5 0.3 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SNAP PF14938.6 RLN89109.1 - 5.3e-86 288.5 27.3 9.7e-86 287.7 27.3 1.4 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP DUF4145 PF13643.6 RLN89109.1 - 0.00027 21.0 0.5 0.0009 19.3 0.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4145) TPR_16 PF13432.6 RLN89109.1 - 0.00034 21.2 7.2 0.017 15.8 1.2 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 RLN89109.1 - 0.00046 19.7 5.3 0.00086 18.8 4.7 1.6 1 1 1 2 2 2 2 MalT-like TPR region TPR_14 PF13428.6 RLN89109.1 - 0.0019 18.8 9.4 0.4 11.6 0.6 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN89109.1 - 0.0024 17.8 7.9 0.22 11.6 1.5 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN89109.1 - 0.0042 16.8 14.4 0.0068 16.2 3.6 4.5 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 RLN89109.1 - 0.0043 17.1 3.1 0.0043 17.1 3.1 5.6 4 1 1 6 6 6 1 Tetratricopeptide repeat MIT PF04212.18 RLN89109.1 - 0.0045 17.0 15.7 0.054 13.6 5.0 3.9 1 1 3 4 4 4 2 MIT (microtubule interacting and transport) domain Phage_term_smal PF05944.12 RLN89109.1 - 0.015 15.3 0.4 0.037 14.0 0.2 1.7 1 1 0 1 1 1 0 Phage small terminase subunit UDPG_MGDP_dh_C PF03720.15 RLN89109.1 - 0.019 15.4 0.6 0.065 13.7 0.1 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain TPR_8 PF13181.6 RLN89109.1 - 0.02 15.1 2.0 0.02 15.1 2.0 3.9 4 1 1 5 5 4 0 Tetratricopeptide repeat PPR_1 PF12854.7 RLN89109.1 - 0.032 14.0 0.1 0.18 11.5 0.0 2.3 2 0 0 2 2 2 0 PPR repeat TPR_6 PF13174.6 RLN89109.1 - 0.048 14.3 10.1 0.19 12.4 0.8 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.9 RLN89109.1 - 0.055 13.2 5.9 0.033 13.9 2.8 2.1 1 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_12 PF13424.6 RLN89109.1 - 0.25 11.6 14.1 0.065 13.5 1.7 3.8 1 1 2 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN89109.1 - 0.45 11.1 13.0 7.4 7.2 2.7 3.5 2 1 1 3 3 2 0 Tetratricopeptide repeat DUF2225 PF09986.9 RLN89109.1 - 1.1 9.0 10.1 0.31 10.7 5.8 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF3958 PF13125.6 RLN89109.1 - 3.6 7.8 10.7 20 5.5 1.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3958) SBP_bac_6 PF13343.6 RLN89110.1 - 2.9e-14 53.1 0.2 2.2e-11 43.6 0.1 2.2 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 RLN89110.1 - 8.4e-11 42.2 4.7 1.5e-10 41.4 4.7 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 RLN89110.1 - 5.5e-08 33.1 5.4 3.6e-07 30.4 5.4 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 RLN89110.1 - 0.0033 17.2 0.1 0.011 15.5 0.1 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Trypsin_2 PF13365.6 RLN89112.1 - 2.9e-13 51.0 0.1 5.3e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 RLN89112.1 - 0.00027 20.8 5.6 0.003 17.4 5.9 2.4 2 1 0 2 2 2 1 Trypsin Methyltransf_25 PF13649.6 RLN89114.1 - 1.6e-14 54.4 0.0 5.1e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN89114.1 - 3.5e-14 53.2 0.0 9.4e-14 51.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN89114.1 - 4.6e-12 45.8 0.0 2.3e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 RLN89114.1 - 1.3e-09 38.7 0.0 2.4e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN89114.1 - 6.2e-08 32.6 0.0 1.3e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN89114.1 - 4e-07 30.0 0.0 1.1e-06 28.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN89114.1 - 0.013 15.0 0.0 0.046 13.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain PSD3 PF07626.11 RLN89114.1 - 0.025 15.0 0.1 15 6.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1587) Trypsin_2 PF13365.6 RLN89115.1 - 9.8e-16 59.0 0.7 1.9e-15 58.1 0.7 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 RLN89115.1 - 1.3e-06 28.4 3.9 4.4e-06 26.7 3.9 1.8 1 1 0 1 1 1 1 Trypsin Peptidase_C3 PF00548.20 RLN89115.1 - 0.0014 18.6 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 3C cysteine protease (picornain 3C) UCH PF00443.29 RLN89116.1 - 8.2e-42 143.5 0.0 1.2e-41 143.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN89116.1 - 1.5e-17 64.2 0.0 7e-15 55.4 0.0 2.4 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.32 RLN89116.1 - 7.3e-08 33.0 10.1 0.067 14.1 0.1 6.7 6 0 0 6 6 6 2 WD domain, G-beta repeat Peptidase_C98 PF15499.6 RLN89116.1 - 0.038 13.5 0.4 6.5 6.1 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase CTNNBL PF08216.11 RLN89117.1 - 2e-25 89.0 0.0 6.1e-25 87.4 0.0 1.9 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear DUF3446 PF11928.8 RLN89117.1 - 3.6 8.0 7.5 3.1 8.2 0.5 3.3 3 0 0 3 3 3 0 Early growth response N-terminal domain Tubulin_C PF03953.17 RLN89118.1 - 4.7e-15 55.9 0.0 6.7e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Ion_trans_2 PF07885.16 RLN89119.1 - 2.2e-10 40.3 6.2 3.9e-10 39.5 6.2 1.3 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 RLN89119.1 - 0.00088 18.6 0.6 0.0013 18.0 0.6 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 RLN89120.1 - 1.5e-08 34.2 1.1 2.6e-08 33.4 1.1 1.3 1 0 0 1 1 1 1 Ion transport protein Myb_DNA-binding PF00249.31 RLN89121.1 - 1.6e-09 37.8 0.2 0.00014 22.0 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN89121.1 - 1.2e-05 25.5 0.2 0.00069 19.8 0.0 2.6 1 1 1 2 2 2 1 Myb-like DNA-binding domain SLIDE PF09111.10 RLN89121.1 - 0.036 14.1 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 SLIDE SDA1 PF05285.12 RLN89121.1 - 1.3 8.4 36.8 0.17 11.2 13.1 3.4 3 0 0 3 3 3 0 SDA1 PI3K_1B_p101 PF10486.9 RLN89121.1 - 4.5 4.9 10.1 6.4 4.4 0.6 2.4 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RNR_Alpha PF17975.1 RLN89122.1 - 5.4e-40 136.0 0.1 1.8e-39 134.3 0.1 1.9 2 0 0 2 2 2 1 Ribonucleotide reductase alpha domain Ribonuc_red_lgC PF02867.15 RLN89122.1 - 9.9e-09 34.3 0.0 0.002 16.8 0.1 3.3 3 0 0 3 3 3 3 Ribonucleotide reductase, barrel domain DEPP PF15343.6 RLN89123.1 - 0.019 15.0 1.5 0.034 14.2 0.5 1.8 1 1 1 2 2 2 0 Decidual protein induced by progesterone family RRM_1 PF00076.22 RLN89124.1 - 3.5e-06 26.7 0.0 5.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC2_membrane PF01061.24 RLN89125.1 - 2.6e-28 98.9 25.4 2.6e-28 98.9 25.4 1.6 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN89125.1 - 1.1e-12 47.7 0.2 6.7e-11 41.9 0.0 3.1 3 0 0 3 3 3 1 CDR ABC transporter PDR_assoc PF08370.11 RLN89125.1 - 0.035 13.8 0.0 0.035 13.8 0.0 2.5 2 1 0 2 2 2 0 Plant PDR ABC transporter associated Methyltransf_23 PF13489.6 RLN89126.1 - 6.1e-16 58.7 0.0 2.3e-15 56.8 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN89126.1 - 1.6e-13 51.2 0.0 3.8e-13 50.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN89126.1 - 1.6e-13 51.2 0.0 3.2e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN89126.1 - 2.6e-09 37.1 0.0 5.1e-09 36.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN89126.1 - 2.3e-08 34.6 0.0 4.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN89126.1 - 7.6e-06 25.6 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 RLN89126.1 - 0.00095 18.4 0.0 0.0042 16.3 0.0 2.0 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_8 PF05148.15 RLN89126.1 - 0.003 17.5 0.1 0.024 14.5 0.1 2.0 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_PK PF05891.12 RLN89126.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.18 RLN89126.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Peptidase_S10 PF00450.22 RLN89127.1 - 7.1e-92 309.0 0.0 4.7e-91 306.3 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 RLN89127.1 - 0.00091 19.9 0.0 0.006 17.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN89127.1 - 0.023 13.9 0.0 0.33 10.2 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 ETF_QO PF05187.13 RLN89129.1 - 9.6e-37 125.3 0.1 1.6e-36 124.5 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 RLN89129.1 - 4.9e-05 22.6 0.9 0.0023 17.1 1.1 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 RLN89129.1 - 0.00057 19.6 0.3 1.4 8.4 0.0 3.0 2 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 RLN89129.1 - 0.00085 18.6 0.0 0.013 14.7 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 RLN89129.1 - 0.0036 17.3 0.0 0.0065 16.5 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 RLN89129.1 - 0.0047 16.0 0.1 0.0072 15.4 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Fer4_7 PF12838.7 RLN89129.1 - 0.0049 17.4 3.0 0.016 15.8 3.0 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain NAD_binding_8 PF13450.6 RLN89129.1 - 0.0098 16.1 0.0 0.0098 16.1 0.0 2.7 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 RLN89129.1 - 0.016 14.4 0.0 0.039 13.2 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Tom7 PF08038.12 RLN89129.1 - 0.018 14.7 0.2 0.044 13.5 0.2 1.6 1 0 0 1 1 1 0 TOM7 family HI0933_like PF03486.14 RLN89129.1 - 0.08 11.6 0.3 0.12 11.0 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 RLN89129.1 - 0.09 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 RLN89129.1 - 0.11 11.7 0.2 0.16 11.2 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RLN89129.1 - 0.2 12.3 1.1 4.9 7.8 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RLN89129.1 - 0.21 10.7 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DnaJ_C PF01556.18 RLN89130.1 - 1.5e-36 125.7 0.1 1.9e-36 125.4 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RLN89130.1 - 5.5e-17 61.7 0.3 1.1e-16 60.6 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain TGS PF02824.21 RLN89131.1 - 6.8e-08 32.4 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 TGS domain MTHFR PF02219.17 RLN89132.1 - 1.5e-91 306.7 0.0 2.4e-91 306.0 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF1712 PF08217.11 RLN89132.1 - 0.0012 17.5 0.0 0.0035 15.9 0.0 1.7 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1712) APG6_N PF17675.1 RLN89132.1 - 0.047 14.2 5.5 0.052 14.1 1.7 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Peptidase_C1 PF00112.23 RLN89134.1 - 0.004 17.3 0.0 0.0089 16.1 0.0 1.5 2 0 0 2 2 2 1 Papain family cysteine protease HECT PF00632.25 RLN89135.1 - 1.8e-92 310.1 0.0 3.2e-92 309.3 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Peptidase_C1 PF00112.23 RLN89136.1 - 0.0072 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Papain family cysteine protease Phage_holin_3_6 PF07332.11 RLN89138.1 - 0.026 14.6 0.5 0.026 14.6 0.5 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III NVEALA PF14055.6 RLN89138.1 - 2.1 8.4 5.7 0.46 10.5 0.4 2.5 3 0 0 3 3 3 0 NVEALA protein DUF4148 PF13663.6 RLN89138.1 - 3.2 8.0 11.8 6.6 7.0 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4148) MULE PF10551.9 RLN89140.1 - 7.8e-10 39.1 0.0 1.9e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain zf-CCHC PF00098.23 RLN89140.1 - 0.065 13.3 2.3 0.21 11.7 2.3 2.0 1 0 0 1 1 1 0 Zinc knuckle SWIM PF04434.17 RLN89140.1 - 0.073 12.8 0.1 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 SWIM zinc finger zf-CCHC_4 PF14392.6 RLN89140.1 - 0.23 11.2 3.0 0.24 11.1 1.2 1.9 2 0 0 2 2 2 0 Zinc knuckle Ank_4 PF13637.6 RLN89142.1 - 1.4e-09 38.2 1.5 3.9e-06 27.3 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN89142.1 - 3e-09 37.0 4.4 3.9e-08 33.4 0.7 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN89142.1 - 8.5e-09 35.9 1.6 2e-08 34.7 1.6 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN89142.1 - 1.8e-05 24.7 2.1 0.38 11.4 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 RLN89142.1 - 0.00043 20.6 4.8 0.014 15.8 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat Anoctamin PF04547.12 RLN89142.1 - 0.26 10.1 0.1 0.41 9.4 0.1 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel Choline_kinase PF01633.20 RLN89143.1 - 2.9e-54 183.9 0.0 3.8e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 RLN89143.1 - 7.6e-12 45.7 0.0 4e-11 43.3 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 RLN89143.1 - 0.004 16.5 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.25 RLN89144.1 - 9.8e-44 149.7 0.0 8.9e-41 140.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89144.1 - 1.6e-43 148.9 0.0 6.5e-42 143.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN89144.1 - 0.0011 17.8 0.0 0.0029 16.4 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 RLN89144.1 - 0.016 14.8 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 RLN89144.1 - 0.02 14.8 2.9 0.11 12.5 2.9 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family OTU PF02338.19 RLN89145.1 - 4.2e-14 53.1 0.0 9.8e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 RLN89145.1 - 0.00018 21.1 0.0 0.27 10.7 0.0 2.7 2 0 0 2 2 2 2 Peptidase C65 Otubain HIP1_clath_bdg PF16515.5 RLN89145.1 - 6.7 7.4 31.6 4.7 7.9 2.2 4.5 3 1 1 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 UPF0242 PF06785.11 RLN89145.1 - 9.3 6.3 20.5 4 7.5 1.6 3.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF4203 PF13886.6 RLN89147.1 - 3e-32 111.9 25.9 3.8e-32 111.6 25.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Caps_synth_CapC PF14102.6 RLN89147.1 - 0.57 10.6 12.6 0.15 12.5 8.9 2.0 2 0 0 2 2 2 0 Capsule biosynthesis CapC Ank_2 PF12796.7 RLN89148.1 - 6.2e-40 135.7 5.2 2.4e-07 31.2 0.1 6.8 3 1 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN89148.1 - 1.3e-38 130.8 12.0 5.8e-07 29.9 0.0 10.7 6 5 6 12 12 12 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN89148.1 - 1.3e-34 117.8 18.0 0.0006 20.1 0.0 13.7 5 1 9 14 14 14 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN89148.1 - 2.8e-19 67.2 0.1 1.1 10.1 0.0 13.4 16 0 0 16 16 16 2 Ankyrin repeat Ank PF00023.30 RLN89148.1 - 0.00021 21.6 0.1 87 3.8 0.1 7.6 6 2 1 7 7 7 0 Ankyrin repeat DUF5049 PF16468.5 RLN89148.1 - 0.00034 20.5 0.0 9.3 6.2 0.0 5.8 4 1 2 6 6 6 1 Domain of unknown function (DUF5049) DUF1979 PF09322.10 RLN89148.1 - 0.0011 18.9 0.7 2.1 8.3 0.0 4.3 6 0 0 6 6 6 2 Domain of unknown function (DUF1979) DUF3322 PF11795.8 RLN89148.1 - 0.89 9.5 7.5 54 3.7 0.0 5.7 3 3 5 8 8 8 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Ank_4 PF13637.6 RLN89149.1 - 2.5e-41 139.5 27.3 5.9e-06 26.7 0.1 12.9 8 3 5 13 13 13 11 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN89149.1 - 3.5e-38 130.1 13.3 1.2e-08 35.4 0.3 7.5 3 2 2 8 8 8 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN89149.1 - 8.6e-37 124.7 26.1 0.019 15.2 0.1 16.4 3 2 14 17 17 17 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN89149.1 - 9.6e-27 90.1 4.8 11 7.0 0.0 16.9 16 2 2 18 18 18 2 Ankyrin repeat DUF5049 PF16468.5 RLN89149.1 - 0.00027 20.7 0.0 12 5.9 0.0 6.6 5 2 2 7 7 7 1 Domain of unknown function (DUF5049) Ank PF00023.30 RLN89149.1 - 0.0018 18.6 5.6 1.2e+02 3.4 0.1 9.1 4 4 1 5 5 5 0 Ankyrin repeat DUF4388 PF14332.6 RLN89149.1 - 0.022 15.0 0.1 33 4.8 0.0 4.4 5 1 1 6 6 6 0 Domain of unknown function (DUF4388) DUF1843 PF08898.10 RLN89149.1 - 1.1 9.8 18.6 64 4.2 1.1 8.3 9 1 1 10 10 10 0 Domain of unknown function (DUF1843) Pkinase PF00069.25 RLN89151.1 - 2.2e-44 151.8 0.0 2.7e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89151.1 - 4.7e-29 101.4 0.0 6.1e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN89151.1 - 0.0014 18.6 1.7 0.0024 17.8 0.1 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN89151.1 - 0.015 14.3 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 RLN89151.1 - 0.023 13.5 0.0 0.032 13.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 RLN89151.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RLN89151.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family MFS_1 PF07690.16 RLN89152.1 - 1.3e-06 27.6 27.5 1.7e-06 27.3 26.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily NDUF_B12 PF08122.12 RLN89152.1 - 0.22 11.6 1.3 14 5.8 0.8 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family cNMP_binding PF00027.29 RLN89153.1 - 2.2e-13 50.1 0.1 2e-08 34.2 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN89153.1 - 0.0004 19.7 6.3 0.00062 19.1 6.3 1.3 1 0 0 1 1 1 1 Ion transport protein CactinC_cactus PF09732.9 RLN89156.1 - 8.8e-32 109.7 0.8 9.6e-32 109.6 0.8 1.0 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Glyco_hydro_92 PF07971.12 RLN89157.1 - 0.021 13.8 0.0 0.023 13.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 Cation_ATPase_C PF00689.21 RLN89157.1 - 0.56 9.9 11.6 0.098 12.4 3.2 2.0 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Myosin_head PF00063.21 RLN89158.1 - 7.3e-213 708.6 0.0 9.9e-213 708.1 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 RLN89158.1 - 1.9e-06 27.2 30.5 0.025 14.3 0.1 5.8 5 0 0 5 5 5 5 IQ calmodulin-binding motif AAA_16 PF13191.6 RLN89158.1 - 0.039 14.3 0.0 0.039 14.3 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 RLN89158.1 - 0.12 12.9 0.1 0.61 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 RLN89158.1 - 0.12 12.6 3.0 0.22 11.8 0.0 3.0 2 1 1 3 3 3 0 AAA domain ZapB PF06005.12 RLN89158.1 - 0.52 10.8 29.8 1.4 9.4 2.7 4.9 3 1 1 4 4 4 0 Cell division protein ZapB UPF0184 PF03670.13 RLN89158.1 - 1.5 9.3 6.6 1.2 9.5 0.4 2.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Lzipper-MIP1 PF14389.6 RLN89158.1 - 3.3 8.1 20.3 0.21 11.9 5.2 3.6 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 HALZ PF02183.18 RLN89158.1 - 7.4 6.9 16.4 13 6.1 0.2 4.8 4 0 0 4 4 4 0 Homeobox associated leucine zipper DOG1 PF14144.6 RLN89158.1 - 8.1 6.8 6.3 34 4.8 0.4 2.9 2 0 0 2 2 2 0 Seed dormancy control CLPTM1 PF05602.12 RLN89160.1 - 0.16 10.9 0.1 0.28 10.2 0.1 1.3 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) MULE PF10551.9 RLN89164.1 - 4.8e-12 46.1 0.1 1.3e-11 44.7 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 RLN89164.1 - 0.021 15.5 0.1 0.054 14.2 0.1 1.7 1 0 0 1 1 1 0 FAR1 DNA-binding domain Paf1 PF03985.13 RLN89164.1 - 2.3 7.2 3.9 3.6 6.5 3.9 1.2 1 0 0 1 1 1 0 Paf1 OrfB_Zn_ribbon PF07282.11 RLN89166.1 - 7.1e-07 29.1 2.0 0.023 14.6 0.2 2.5 2 0 0 2 2 2 2 Putative transposase DNA-binding domain DUF3387 PF11867.8 RLN89166.1 - 0.21 10.9 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) DUF1126 PF06565.12 RLN89167.1 - 2.6e-87 287.6 0.1 4.3e-30 103.6 0.1 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain RPN7 PF10602.9 RLN89168.1 - 6.9e-45 152.9 2.7 4.7e-44 150.2 2.7 2.1 1 1 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 RLN89168.1 - 1.7e-14 54.2 0.0 5.1e-14 52.7 0.0 1.9 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.6 RLN89168.1 - 0.0067 16.4 0.0 0.93 9.7 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN89168.1 - 0.018 15.3 1.5 0.6 10.4 0.5 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN89168.1 - 0.031 14.4 3.5 4.7 7.6 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat WD-3 PF09765.9 RLN89169.1 - 4.3e-78 262.5 0.0 5.5e-78 262.2 0.0 1.0 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 RLN89169.1 - 1.1e-26 92.8 1.9 4.5e-26 90.8 1.9 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 RLN89169.1 - 0.0033 17.7 3.0 0.0033 17.7 3.0 2.7 3 0 0 3 3 3 1 Ring finger domain zf-ANAPC11 PF12861.7 RLN89169.1 - 0.13 12.3 0.2 0.13 12.3 0.2 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 RLN89169.1 - 0.38 11.1 2.2 1 9.7 2.2 1.7 1 1 0 1 1 1 0 RING-like domain zf-rbx1 PF12678.7 RLN89169.1 - 0.49 10.7 5.5 1.6 9.1 5.5 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-HC5HC2H PF13771.6 RLN89169.1 - 0.95 9.8 2.9 2.1 8.7 1.5 2.2 2 1 0 2 2 2 0 PHD-like zinc-binding domain NCBP3 PF10309.9 RLN89170.1 - 2.1e-15 56.3 0.0 4.2e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Methyltransf_FA PF12248.8 RLN89170.1 - 2.4e-07 31.0 0.0 7.4e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Farnesoic acid 0-methyl transferase RNA_bind PF08675.11 RLN89170.1 - 6.3e-05 22.9 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 RNA binding domain Tho1_MOS11_C PF18592.1 RLN89170.1 - 0.29 11.0 5.3 6.3 6.7 0.2 3.3 2 1 1 3 3 3 0 Tho1/MOS11 C-terminal domain DUF842 PF05811.13 RLN89171.1 - 2.1e-45 153.6 13.6 2.3e-45 153.5 13.6 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) GF_recep_IV PF14843.6 RLN89171.1 - 0.00099 18.9 9.6 0.0013 18.5 9.6 1.2 1 0 0 1 1 1 1 Growth factor receptor domain IV 7TMR-HDED PF07697.11 RLN89171.1 - 0.028 14.5 0.4 0.028 14.5 0.4 1.2 1 0 0 1 1 1 0 7TM-HD extracellular HTH_AsnC-type PF13404.6 RLN89171.1 - 0.051 13.4 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain zf-Tim10_DDP PF02953.15 RLN89171.1 - 0.18 11.5 19.1 0.13 11.9 3.9 3.5 2 1 1 3 3 3 0 Tim10/DDP family zinc finger Col_cuticle_N PF01484.17 RLN89171.1 - 0.26 11.4 2.3 0.31 11.1 0.9 1.9 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain GIT_CC PF16559.5 RLN89171.1 - 0.72 9.8 6.4 0.92 9.4 4.4 2.3 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Vicilin_N PF04702.12 RLN89171.1 - 1.9 8.3 18.9 2.7 7.8 18.9 1.4 1 1 0 1 1 1 0 Vicilin N terminal region DHHC PF01529.20 RLN89172.1 - 1.2e-19 70.8 7.4 1.2e-19 70.8 7.4 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase SARAF PF06682.12 RLN89172.1 - 0.037 13.7 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF1772 PF08592.11 RLN89172.1 - 0.075 13.4 0.3 0.45 10.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF3043 PF11241.8 RLN89172.1 - 3.5 7.6 0.0 3.5 7.6 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3043) FXMRP1_C_core PF12235.8 RLN89173.1 - 0.069 13.8 1.3 0.081 13.6 0.2 1.6 1 1 0 1 1 1 0 Fragile X-related 1 protein core C terminal Herpes_capsid PF06112.11 RLN89173.1 - 5.2 7.1 12.2 8.4 6.4 12.2 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PH PF00169.29 RLN89174.1 - 3.6e-05 24.2 0.0 6.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 PH domain FYVE PF01363.21 RLN89174.1 - 0.0037 17.4 15.5 0.008 16.3 15.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger Pectate_lyase PF03211.13 RLN89175.1 - 1.9e-81 272.5 7.4 4.1e-81 271.4 7.4 1.5 1 0 0 1 1 1 1 Pectate lyase CDC45 PF02724.14 RLN89175.1 - 0.46 8.7 6.7 0.64 8.2 6.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 RLN89175.1 - 0.65 8.0 9.4 0.75 7.9 9.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Hamartin PF04388.12 RLN89175.1 - 2.3 6.8 11.7 2.9 6.5 11.7 1.1 1 0 0 1 1 1 0 Hamartin protein SAPS PF04499.15 RLN89175.1 - 5.8 5.6 10.2 7.6 5.2 10.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mitofilin PF09731.9 RLN89175.1 - 6.2 5.5 19.7 8.3 5.1 19.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Plasmodium_Vir PF05795.11 RLN89175.1 - 6.6 6.0 9.9 9.2 5.6 9.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PPP4R2 PF09184.11 RLN89175.1 - 7.6 6.0 17.2 11 5.5 17.2 1.2 1 0 0 1 1 1 0 PPP4R2 Aa_trans PF01490.18 RLN89176.1 - 2.7e-62 210.8 30.8 9.9e-62 208.9 30.8 1.7 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Peptidase_S10 PF00450.22 RLN89177.1 - 4e-78 263.7 0.0 3e-71 241.0 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase Herpes_gE PF02480.16 RLN89177.1 - 0.00063 18.6 0.1 0.00097 18.0 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E FAM176 PF14851.6 RLN89177.1 - 0.052 13.2 2.6 0.3 10.8 0.2 2.2 2 0 0 2 2 2 0 FAM176 family Myc_N PF01056.18 RLN89177.1 - 0.084 12.8 1.6 0.14 12.0 1.6 1.4 1 0 0 1 1 1 0 Myc amino-terminal region UBA PF00627.31 RLN89178.1 - 1.1e-31 108.2 6.1 1.7e-16 59.7 0.0 3.5 3 0 0 3 3 3 2 UBA/TS-N domain XPC-binding PF09280.11 RLN89178.1 - 4.3e-24 84.0 8.7 4.3e-24 84.0 8.7 2.3 2 1 0 2 2 2 1 XPC-binding domain ubiquitin PF00240.23 RLN89178.1 - 4.2e-15 55.2 0.6 9.6e-15 54.1 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 RLN89178.1 - 0.0033 17.2 0.1 0.011 15.6 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 RLN89178.1 - 0.0037 17.0 0.0 0.4 10.5 0.0 2.4 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain DUF3135 PF11333.8 RLN89178.1 - 0.0048 17.1 2.3 0.11 12.7 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3135) DUF1421 PF07223.11 RLN89178.1 - 0.011 15.5 0.1 0.64 9.9 0.0 3.0 3 0 0 3 3 3 0 UBA-like domain (DUF1421) Ubiquitin_5 PF18037.1 RLN89178.1 - 0.022 15.1 0.1 0.037 14.4 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 RLN89178.1 - 0.025 15.1 0.0 0.055 14.0 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain WIYLD PF10440.9 RLN89178.1 - 0.027 14.2 0.0 6.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Ubiquitin_2 PF14560.6 RLN89178.1 - 0.048 14.1 0.2 0.16 12.5 0.1 1.9 2 1 0 2 2 2 0 Ubiquitin-like domain CUE PF02845.16 RLN89178.1 - 0.066 12.9 0.0 0.58 9.9 0.0 2.6 2 0 0 2 2 2 0 CUE domain Rad60-SLD_2 PF13881.6 RLN89178.1 - 0.18 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like SARG PF15385.6 RLN89178.1 - 1.2 8.3 9.8 1.9 7.6 9.8 1.4 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein DUF3306 PF11748.8 RLN89178.1 - 2.4 9.0 9.4 2 9.3 6.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3306) Pkinase PF00069.25 RLN89179.1 - 3e-70 236.6 0.0 3.6e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89179.1 - 2.7e-33 115.4 0.0 2e-32 112.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RLN89179.1 - 1.1e-06 27.8 0.8 2.1e-06 27.0 0.8 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RLN89179.1 - 0.00059 19.2 0.0 0.0017 17.7 0.0 1.7 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 RLN89179.1 - 0.02 14.5 0.6 5 6.7 0.0 2.4 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RLN89179.1 - 0.029 14.3 0.1 1.4 8.8 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN89179.1 - 0.051 12.3 0.0 0.14 10.9 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 RLN89179.1 - 0.1 11.9 1.0 0.24 10.7 1.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FeoB_N PF02421.18 RLN89179.1 - 0.13 11.8 0.2 0.21 11.1 0.2 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Biopterin_H PF00351.21 RLN89180.1 - 1.8e-42 145.6 0.3 3.7e-34 118.3 0.0 2.0 1 1 1 2 2 2 2 Biopterin-dependent aromatic amino acid hydroxylase DUF807 PF05660.11 RLN89180.1 - 0.1 12.5 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF807) ACT PF01842.25 RLN89181.1 - 1e-05 25.2 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 ACT domain APG6 PF04111.12 RLN89182.1 - 2e-47 161.4 0.2 3e-47 160.9 0.2 1.2 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 RLN89182.1 - 1.7e-05 25.3 7.4 1.7e-05 25.3 7.4 1.6 2 0 0 2 2 2 1 Apg6 coiled-coil region DUF3995 PF13160.6 RLN89183.1 - 0.12 12.7 8.9 0.3 11.4 8.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) zf-MYND PF01753.18 RLN89187.1 - 3.6e-11 43.0 15.9 3.6e-11 43.0 15.9 1.5 2 0 0 2 2 2 1 MYND finger WD40 PF00400.32 RLN89188.1 - 1.6e-12 47.7 6.0 0.0008 20.2 0.0 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat Lactonase PF10282.9 RLN89188.1 - 0.00057 19.2 0.0 0.00095 18.5 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller ANAPC4_WD40 PF12894.7 RLN89188.1 - 0.0039 17.4 0.0 9.2 6.6 0.0 3.8 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 RLN89188.1 - 0.038 13.6 0.0 1.5 8.4 0.0 2.4 2 1 0 2 2 2 0 PQQ-like domain Methyltransf_23 PF13489.6 RLN89189.1 - 2.6e-22 79.4 0.0 1.8e-20 73.5 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN89189.1 - 3e-22 79.1 0.1 9.9e-18 64.7 0.0 4.0 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 RLN89189.1 - 5.4e-22 78.2 0.8 2.6e-17 63.2 0.0 3.9 4 0 0 4 4 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 RLN89189.1 - 3.2e-19 69.2 0.0 3e-14 53.1 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain RRM_1 PF00076.22 RLN89189.1 - 1.1e-16 60.4 0.0 3.2e-16 58.9 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_12 PF08242.12 RLN89189.1 - 1.4e-15 57.8 0.7 2.2e-11 44.4 0.0 3.7 4 0 0 4 4 4 2 Methyltransferase domain CMAS PF02353.20 RLN89189.1 - 8.8e-14 51.4 0.1 1.9e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 RLN89189.1 - 1.2e-08 34.5 0.0 2.1e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CheR PF01739.18 RLN89189.1 - 1.5e-08 34.4 0.0 0.0038 16.7 0.0 2.9 2 1 1 3 3 3 2 CheR methyltransferase, SAM binding domain PCMT PF01135.19 RLN89189.1 - 5.8e-07 29.5 0.0 1.6e-06 28.0 0.0 1.7 2 0 0 2 2 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPMT PF05724.11 RLN89189.1 - 3.1e-06 27.0 0.0 6.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.11 RLN89189.1 - 1.7e-05 23.9 0.0 1.7e-05 23.9 0.0 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 RLN89189.1 - 0.00028 20.5 0.0 0.0014 18.3 0.0 2.1 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 RLN89189.1 - 0.0027 17.0 0.0 1.9 7.8 0.0 3.1 3 0 0 3 3 3 1 O-methyltransferase domain MTS PF05175.14 RLN89189.1 - 0.009 15.6 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain RRM_7 PF16367.5 RLN89189.1 - 0.019 15.1 0.0 0.18 11.9 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif TPR_12 PF13424.6 RLN89189.1 - 0.025 14.9 2.7 0.4 11.0 2.5 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat DOT1 PF08123.13 RLN89189.1 - 0.039 13.5 0.5 0.23 11.0 0.1 2.4 4 0 0 4 4 3 0 Histone methylation protein DOT1 Methyltransf_32 PF13679.6 RLN89189.1 - 0.06 13.3 0.0 0.06 13.3 0.0 3.0 3 1 0 3 3 3 0 Methyltransferase domain TPR_10 PF13374.6 RLN89189.1 - 0.32 10.9 2.3 2 8.4 0.1 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat RRN3 PF05327.11 RLN89189.1 - 1.5 7.3 4.3 2.8 6.4 4.3 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF5427 PF10310.9 RLN89189.1 - 2.9 6.8 15.6 0.21 10.5 10.6 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5427) eIF3_subunit PF08597.10 RLN89189.1 - 3.5 7.5 19.2 9.9 6.0 19.2 1.7 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Dimer_Tnp_hAT PF05699.14 RLN89190.1 - 2.4e-08 33.6 0.0 7.9e-08 32.0 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 RLN89190.1 - 0.00072 19.5 0.4 0.0016 18.4 0.4 1.7 1 0 0 1 1 1 1 BED zinc finger RabGAP-TBC PF00566.18 RLN89191.1 - 2.2e-46 158.2 0.0 5e-46 157.1 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PDZ PF00595.24 RLN89191.1 - 2.4e-06 27.8 0.0 5.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RLN89191.1 - 2.8e-06 27.1 0.1 7e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 PDZ domain C2 PF00168.30 RLN89192.1 - 2.4e-09 37.4 0.0 1.9e-08 34.5 0.0 2.3 2 0 0 2 2 2 1 C2 domain zf-B_box PF00643.24 RLN89193.1 - 0.00095 19.3 4.9 0.00095 19.3 4.9 1.6 2 0 0 2 2 2 1 B-box zinc finger CEBP_ZZ PF16366.5 RLN89193.1 - 0.0035 17.5 4.4 0.0084 16.3 4.4 1.6 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain IQ PF00612.27 RLN89193.1 - 0.082 12.7 4.4 0.23 11.4 4.4 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Fzo_mitofusin PF04799.13 RLN89193.1 - 0.22 11.1 6.0 0.41 10.2 6.0 1.4 1 0 0 1 1 1 0 fzo-like conserved region Tweety PF04906.13 RLN89193.1 - 0.46 9.1 2.1 0.69 8.5 2.1 1.2 1 0 0 1 1 1 0 Tweety dCache_2 PF08269.11 RLN89193.1 - 2.1 7.4 4.0 2.8 7.0 4.0 1.2 1 0 0 1 1 1 0 Cache domain DUF2570 PF10828.8 RLN89193.1 - 5.1 7.0 9.6 22 4.9 9.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Acetyltransf_1 PF00583.25 RLN89194.1 - 3.3e-17 62.8 0.2 4.9e-17 62.2 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RLN89194.1 - 2.5e-09 37.1 0.4 3.5e-09 36.7 0.4 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN89194.1 - 3.3e-09 37.0 0.1 5.1e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN89194.1 - 5.1e-06 26.4 0.1 8.7e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 RLN89194.1 - 0.0012 19.0 0.6 0.0021 18.2 0.2 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 RLN89194.1 - 0.0036 18.0 0.1 0.0064 17.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 RLN89194.1 - 0.0047 16.9 0.1 0.0089 16.0 0.1 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase CCDC84 PF14968.6 RLN89195.1 - 1.4e-51 176.2 4.7 1.4e-51 176.2 4.7 1.6 2 0 0 2 2 2 1 Coiled coil protein 84 ELM2 PF01448.24 RLN89195.1 - 0.013 16.3 0.0 0.039 14.7 0.0 1.8 1 0 0 1 1 1 0 ELM2 domain MULE PF10551.9 RLN89199.1 - 7.1e-13 48.8 0.1 1.6e-12 47.6 0.1 1.7 2 0 0 2 2 2 1 MULE transposase domain FLYWCH PF04500.16 RLN89199.1 - 9.2e-05 22.5 1.4 0.0002 21.4 1.4 1.6 1 0 0 1 1 1 1 FLYWCH zinc finger domain SWIB PF02201.18 RLN89202.1 - 1.5e-18 66.4 0.4 3e-12 46.3 0.1 2.1 2 0 0 2 2 2 2 SWIB/MDM2 domain Trypsin_2 PF13365.6 RLN89203.1 - 3.1e-25 89.8 2.6 6.1e-21 75.9 0.1 2.4 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_1 PF12812.7 RLN89203.1 - 4.1e-16 58.7 0.0 8.1e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 PDZ-like domain PDZ_2 PF13180.6 RLN89203.1 - 1.4e-05 25.3 0.1 0.0085 16.4 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 RLN89203.1 - 7.6e-05 22.5 0.1 0.0028 17.5 0.0 2.8 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 RLN89203.1 - 0.00024 21.4 0.0 0.0021 18.4 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 RLN89203.1 - 0.0013 17.5 0.3 0.0013 17.5 0.3 1.5 2 0 0 2 2 2 1 Peptidase S46 Trypsin PF00089.26 RLN89203.1 - 0.0031 17.3 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 Trypsin Peptidase_S7 PF00949.21 RLN89203.1 - 0.077 12.8 0.4 0.16 11.8 0.4 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.16 RLN89203.1 - 0.093 12.3 0.4 0.14 11.7 0.4 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) MARVEL PF01284.23 RLN89204.1 - 1.8e-11 44.3 14.3 2.4e-11 43.9 14.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain RseC_MucC PF04246.12 RLN89205.1 - 0.38 10.7 4.6 0.44 10.5 3.2 1.7 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC zf-CCHC PF00098.23 RLN89207.1 - 1.3e-15 56.6 37.0 0.00012 22.0 0.4 5.3 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_2 PF13696.6 RLN89207.1 - 0.0027 17.5 8.0 0.038 13.8 0.2 5.3 5 1 0 5 5 5 3 Zinc knuckle zf-CCHC_4 PF14392.6 RLN89207.1 - 0.0052 16.5 31.4 0.19 11.5 1.9 5.2 5 0 0 5 5 5 4 Zinc knuckle zf-C2H2_10 PF16588.5 RLN89207.1 - 2.5 7.9 10.7 0.84 9.4 0.7 2.6 2 0 0 2 2 2 0 C2H2 zinc-finger SUA5 PF03481.13 RLN89208.1 - 0.049 14.2 0.1 0.069 13.7 0.1 1.3 1 0 0 1 1 1 0 Putative GTP-binding controlling metal-binding SCIMP PF15050.6 RLN89208.1 - 0.13 12.7 1.2 0.23 11.9 0.3 1.9 1 1 1 2 2 2 0 SCIMP protein CIAPIN1 PF05093.13 RLN89208.1 - 0.3 11.6 3.6 1.6 9.3 0.3 2.2 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Bindin PF02084.15 RLN89208.1 - 0.48 10.7 5.2 0.56 10.4 4.4 1.5 1 1 0 1 1 1 0 Bindin MCM PF00493.23 RLN89209.1 - 2.4e-74 249.2 0.0 3.9e-74 248.5 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RLN89209.1 - 3.7e-15 55.9 0.2 8.1e-15 54.8 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RLN89209.1 - 9.3e-14 51.6 1.8 2.1e-13 50.5 1.8 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 RLN89209.1 - 4.2e-08 32.8 0.1 0.00013 21.4 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RLN89209.1 - 2.7e-07 30.6 0.0 6e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RLN89209.1 - 0.028 14.8 0.2 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 RLN89209.1 - 0.03 13.7 0.1 0.079 12.3 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.29 RLN89209.1 - 0.05 14.0 0.0 0.13 12.7 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 RLN89209.1 - 0.21 11.3 0.3 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Wbp11 PF09429.10 RLN89210.1 - 2.9e-17 62.8 15.7 2.9e-17 62.8 15.7 2.2 2 0 0 2 2 2 1 WW domain binding protein 11 NpwBP PF12622.7 RLN89210.1 - 8.6e-10 39.2 5.7 8.6e-10 39.2 5.7 5.4 4 3 0 4 4 4 1 mRNA biogenesis factor SDF PF00375.18 RLN89211.1 - 1.4e-66 225.1 29.7 5.6e-66 223.2 29.7 1.7 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family Pkinase PF00069.25 RLN89212.1 - 1.4e-65 221.3 0.0 1.9e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89212.1 - 1.7e-31 109.5 0.0 3.5e-31 108.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 RLN89212.1 - 0.0016 18.4 3.8 0.098 12.6 0.0 3.2 2 1 0 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 RLN89212.1 - 0.0035 16.7 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RLN89212.1 - 0.064 12.0 0.0 0.23 10.2 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 RLN89212.1 - 0.068 12.7 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 RLN89212.1 - 0.09 12.1 0.0 0.23 10.8 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CxC6 PF18721.1 RLN89213.1 - 0.038 14.3 10.6 0.67 10.3 1.3 2.4 1 1 1 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases Ssu72 PF04722.13 RLN89214.1 - 1.2e-39 135.8 0.0 7.9e-26 90.8 0.0 2.1 1 1 1 2 2 2 2 Ssu72-like protein DOPA_dioxygen PF08883.11 RLN89215.1 - 1.3e-29 102.5 0.2 2e-29 101.9 0.2 1.3 1 1 0 1 1 1 1 Dopa 4,5-dioxygenase family SRP54 PF00448.22 RLN89216.1 - 4.3e-51 173.3 0.0 7.9e-51 172.5 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 RLN89216.1 - 4e-43 148.4 6.1 5.4e-43 148.0 6.1 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal MeaB PF03308.16 RLN89216.1 - 3.5e-08 32.8 0.0 8.6e-08 31.5 0.0 1.5 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 RLN89216.1 - 5.9e-05 23.5 0.0 0.00026 21.4 0.0 2.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 RLN89216.1 - 0.00056 19.7 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 RLN89216.1 - 0.00082 19.3 0.8 0.011 15.7 0.1 2.5 3 0 0 3 3 3 1 NTPase ETF PF01012.21 RLN89216.1 - 0.0016 18.4 0.3 0.082 12.8 0.0 2.7 2 1 1 3 3 3 1 Electron transfer flavoprotein domain MMR_HSR1 PF01926.23 RLN89216.1 - 0.0018 18.3 0.4 0.01 15.9 0.1 2.3 2 1 0 2 2 1 1 50S ribosome-binding GTPase CbiA PF01656.23 RLN89216.1 - 0.0027 17.8 0.0 0.014 15.5 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 RLN89216.1 - 0.026 14.2 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 RLN89216.1 - 0.044 12.9 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Fer4_NifH PF00142.18 RLN89216.1 - 0.048 13.1 0.1 0.094 12.1 0.1 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54_N PF02881.19 RLN89216.1 - 0.078 13.2 0.1 0.27 11.5 0.1 1.9 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain RsgA_GTPase PF03193.16 RLN89216.1 - 0.086 12.7 0.0 0.85 9.5 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 RLN89216.1 - 0.12 12.8 0.0 0.39 11.1 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN89216.1 - 0.15 12.3 0.3 0.53 10.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain A_deaminase PF00962.22 RLN89217.1 - 3.2e-24 85.9 0.0 3.3e-17 62.8 0.1 2.2 2 0 0 2 2 2 2 Adenosine/AMP deaminase Elicitin PF00964.17 RLN89218.1 - 0.00078 19.5 6.3 0.00078 19.5 6.3 1.9 2 0 0 2 2 2 1 Elicitin Pkinase PF00069.25 RLN89219.1 - 2.4e-22 79.6 0.0 3e-18 66.1 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89219.1 - 4e-10 39.4 0.0 7.5e-10 38.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN89219.1 - 5.6e-05 22.6 0.0 7.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN89219.1 - 0.00021 21.3 0.0 0.00096 19.1 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN89219.1 - 0.08 11.7 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TrmO PF01980.16 RLN89223.1 - 7.9e-22 77.7 0.5 2.4e-21 76.2 0.1 2.1 2 1 0 2 2 2 1 tRNA-methyltransferase O SPX PF03105.19 RLN89224.1 - 0.14 12.1 10.7 0.15 12.0 10.7 1.1 1 0 0 1 1 1 0 SPX domain BUD22 PF09073.10 RLN89224.1 - 4.6 6.5 11.5 5.2 6.3 11.5 1.2 1 0 0 1 1 1 0 BUD22 TMEM65 PF10507.9 RLN89225.1 - 0.12 12.3 0.1 0.31 11.0 0.1 1.7 1 0 0 1 1 1 0 Transmembrane protein 65 RabGAP-TBC PF00566.18 RLN89226.1 - 5.3e-26 91.6 3.5 8.6e-26 90.9 3.5 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain C2 PF00168.30 RLN89226.1 - 2.3e-06 27.8 0.0 7.8e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 C2 domain Aldedh PF00171.22 RLN89227.1 - 9.9e-175 581.5 0.1 1.1e-174 581.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2884 PF11101.8 RLN89227.1 - 0.13 11.7 0.1 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) XPG_N PF00752.17 RLN89228.1 - 1.8e-28 98.9 0.0 3.3e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 RLN89228.1 - 4.7e-27 94.2 0.0 9.5e-27 93.2 0.0 1.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 RLN89228.1 - 0.00057 20.4 0.0 0.0015 19.1 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold His_Phos_2 PF00328.22 RLN89229.1 - 3.4e-09 36.5 0.0 6e-07 29.2 0.0 2.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) FH2 PF02181.23 RLN89230.1 - 1.2e-63 215.6 4.2 3.4e-59 200.8 1.0 2.3 2 0 0 2 2 2 2 Formin Homology 2 Domain FYVE PF01363.21 RLN89230.1 - 8.4e-10 38.7 8.7 1.9e-09 37.5 8.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger GOLD_2 PF13897.6 RLN89230.1 - 1.5e-08 35.2 1.7 0.046 14.2 0.9 4.0 3 1 0 3 3 3 2 Golgi-dynamics membrane-trafficking CCDC53 PF10152.9 RLN89230.1 - 1.8e-08 35.0 0.1 1.8e-08 35.0 0.1 2.7 4 0 0 4 4 4 1 Subunit CCDC53 of WASH complex RUN PF02759.19 RLN89230.1 - 7.2e-05 22.8 0.2 0.00021 21.3 0.2 1.8 1 0 0 1 1 1 1 RUN domain FYVE_2 PF02318.16 RLN89230.1 - 0.001 19.3 6.2 0.0045 17.2 6.2 2.1 1 0 0 1 1 1 1 FYVE-type zinc finger Eapp_C PF10238.9 RLN89230.1 - 1.5 8.8 5.4 3.2 7.8 4.2 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein Es2 PF09751.9 RLN89231.1 - 1.3e-28 101.0 7.1 6.1e-20 72.4 1.4 3.2 3 1 1 4 4 4 2 Nuclear protein Es2 Pyr_redox_2 PF07992.14 RLN89231.1 - 3.8e-06 26.3 2.4 7.7e-05 22.1 2.0 2.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RLN89231.1 - 0.0077 15.4 0.9 0.018 14.2 0.1 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 RLN89231.1 - 0.049 12.9 4.6 2.3 7.4 0.7 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF1084 PF06454.11 RLN89233.1 - 5.6e-13 48.9 9.1 2.5e-12 46.8 9.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) Aminotran_1_2 PF00155.21 RLN89234.1 - 4.4e-45 154.4 0.1 3.7e-43 148.1 0.1 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II TK PF00265.18 RLN89234.1 - 0.051 13.4 0.6 2.9 7.7 0.0 2.8 3 0 0 3 3 3 0 Thymidine kinase NTP_transf_3 PF12804.7 RLN89234.1 - 0.073 13.4 0.0 0.15 12.4 0.0 1.5 1 1 0 1 1 1 0 MobA-like NTP transferase domain Cys_Met_Meta_PP PF01053.20 RLN89234.1 - 0.098 11.2 0.0 0.17 10.4 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme G-alpha PF00503.20 RLN89235.1 - 4.9e-57 193.7 0.3 6.5e-57 193.3 0.3 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 RLN89235.1 - 7.1e-08 32.1 2.3 0.00026 20.5 0.0 2.8 2 1 0 3 3 3 2 ADP-ribosylation factor family AAA_29 PF13555.6 RLN89235.1 - 0.029 14.1 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 RLN89235.1 - 0.037 14.2 0.2 5.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 RLN89235.1 - 0.04 13.3 0.1 0.075 12.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 RLN89235.1 - 0.056 13.2 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 RLN89235.1 - 0.1 12.0 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Pkinase PF00069.25 RLN89236.1 - 3.3e-69 233.2 0.0 4.1e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89236.1 - 5.4e-27 94.7 0.0 7.5e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN89236.1 - 0.00029 20.2 0.1 0.32 10.3 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 RLN89236.1 - 0.00032 20.1 0.1 0.00059 19.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN89236.1 - 0.00056 19.9 6.3 0.044 13.7 0.0 2.8 2 2 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 RLN89236.1 - 0.0066 16.1 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 RLN89236.1 - 0.016 14.0 0.4 0.095 11.5 0.0 2.1 2 1 0 3 3 3 0 Fungal protein kinase Noc2 PF03715.13 RLN89237.1 - 2.3e-82 276.6 0.0 2.3e-82 276.6 0.0 2.0 3 0 0 3 3 3 1 Noc2p family Nop14 PF04147.12 RLN89237.1 - 0.031 12.5 0.0 0.031 12.5 0.0 4.4 2 2 2 4 4 4 0 Nop14-like family ERG4_ERG24 PF01222.17 RLN89238.1 - 5.4e-72 242.9 3.6 6.4e-72 242.7 3.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 RLN89238.1 - 0.014 15.0 0.1 0.024 14.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) ABC2_membrane PF01061.24 RLN89239.1 - 7.1e-75 251.0 66.2 1.6e-41 142.0 30.3 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN89239.1 - 1.3e-33 116.4 0.0 8.2e-16 58.8 0.1 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN89239.1 - 2e-07 31.1 0.0 0.86 9.3 0.0 4.1 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN89239.1 - 3.8e-07 30.6 0.1 0.035 14.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 RLN89239.1 - 1.1e-06 28.3 3.2 0.0086 15.8 0.5 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 RLN89239.1 - 2.1e-06 27.3 0.0 0.0029 17.1 0.0 3.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 RLN89239.1 - 3.3e-06 27.1 0.5 0.02 14.8 0.1 2.6 3 0 0 3 3 2 2 RsgA GTPase AAA_22 PF13401.6 RLN89239.1 - 9.3e-05 22.7 0.1 0.41 10.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain PDR_CDR PF06422.12 RLN89239.1 - 0.00014 21.7 0.0 0.00014 21.7 0.0 3.1 4 0 0 4 4 2 1 CDR ABC transporter AAA_25 PF13481.6 RLN89239.1 - 0.0018 17.9 2.7 0.44 10.1 0.5 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RLN89239.1 - 0.0021 18.6 0.8 0.23 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RLN89239.1 - 0.0051 16.5 1.7 0.98 9.1 0.1 2.6 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 RLN89239.1 - 0.0052 16.1 0.8 0.84 8.9 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.29 RLN89239.1 - 0.0066 16.9 0.6 3.3 8.1 0.1 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 RLN89239.1 - 0.011 15.8 1.6 1.6 8.9 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 RLN89239.1 - 0.019 15.5 0.1 8.4 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RLN89239.1 - 0.076 12.9 4.3 2.3 8.1 0.1 2.4 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 RLN89239.1 - 0.11 12.1 2.5 2.1 7.9 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 RLN89239.1 - 0.15 12.2 0.2 8.6 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 RLN89239.1 - 0.22 11.8 0.9 23 5.3 0.1 2.6 2 1 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 RLN89239.1 - 0.24 11.3 0.6 3.3 7.6 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 RLN89239.1 - 0.28 10.9 1.2 9.6 5.9 0.4 2.4 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 RLN89239.1 - 0.35 10.2 1.2 3.9 6.8 0.1 2.2 2 0 0 2 2 2 0 KaiC PduV-EutP PF10662.9 RLN89239.1 - 0.42 10.4 1.2 5.9 6.6 0.5 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC2_membrane_3 PF12698.7 RLN89239.1 - 0.9 8.6 64.2 0.15 11.1 19.7 3.5 3 1 0 3 3 3 0 ABC-2 family transporter protein DUF87 PF01935.17 RLN89239.1 - 4.1 7.4 5.1 40 4.2 1.7 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Aa_trans PF01490.18 RLN89240.1 - 1e-08 34.3 33.4 5.1e-08 32.0 33.4 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein SRTM1 PF15872.5 RLN89240.1 - 0.17 12.0 5.6 0.13 12.4 0.5 2.7 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 ABC2_membrane PF01061.24 RLN89241.1 - 2.5e-75 252.5 63.6 5e-42 143.7 27.6 2.2 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN89241.1 - 1.4e-34 119.6 0.0 4.9e-16 59.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN89241.1 - 3e-08 33.9 0.2 0.18 11.6 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN89241.1 - 4.7e-07 30.3 0.4 0.057 13.8 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 RLN89241.1 - 9.2e-07 28.5 3.1 0.016 14.9 1.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN89241.1 - 1e-06 28.8 0.8 0.021 14.7 0.3 2.4 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 RLN89241.1 - 4.3e-05 23.0 0.1 0.28 10.6 0.1 3.4 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RLN89241.1 - 8.6e-05 22.8 0.0 0.32 11.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.6 RLN89241.1 - 0.00089 19.8 1.6 0.13 12.7 0.2 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 RLN89241.1 - 0.0015 18.1 0.1 0.28 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RLN89241.1 - 0.0029 16.9 0.6 0.43 9.8 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 RLN89241.1 - 0.0031 17.2 0.4 1.6 8.4 0.1 2.6 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 RLN89241.1 - 0.0049 17.3 0.2 5.5 7.4 0.1 3.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RLN89241.1 - 0.006 17.1 0.0 3 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 RLN89241.1 - 0.0089 16.1 0.4 2.4 8.3 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase PDR_CDR PF06422.12 RLN89241.1 - 0.017 15.0 0.0 0.088 12.7 0.0 2.3 2 0 0 2 2 1 0 CDR ABC transporter AAA_24 PF13479.6 RLN89241.1 - 0.024 14.4 0.7 10 5.8 0.4 3.0 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 RLN89241.1 - 0.055 13.6 0.0 3.8 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 RLN89241.1 - 0.066 12.0 1.1 3.7 6.2 0.4 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_5 PF07728.14 RLN89241.1 - 0.085 12.9 0.1 6.9 6.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 RLN89241.1 - 0.11 12.4 4.1 3.9 7.4 0.1 2.4 2 0 0 2 2 2 0 NACHT domain Ploopntkinase3 PF18751.1 RLN89241.1 - 0.15 11.9 0.5 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 RLN89241.1 - 0.18 12.1 0.1 26 5.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 RLN89241.1 - 0.24 11.0 3.3 3 7.4 0.6 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 RLN89241.1 - 0.3 10.8 0.9 6 6.6 0.4 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 RLN89241.1 - 0.47 10.5 2.1 30 4.6 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Mg_chelatase PF01078.21 RLN89241.1 - 0.61 9.4 3.5 14 5.0 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI ABC2_membrane_3 PF12698.7 RLN89241.1 - 0.75 8.8 57.3 0.088 11.9 18.8 3.1 3 0 0 3 3 3 0 ABC-2 family transporter protein ABC2_membrane PF01061.24 RLN89242.1 - 1.1e-74 250.4 74.9 1.9e-44 151.6 27.6 3.1 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN89242.1 - 5e-34 117.8 0.0 9e-16 58.6 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 RLN89242.1 - 6.1e-08 32.5 0.0 6.1e-08 32.5 0.0 3.3 4 0 0 4 4 2 1 CDR ABC transporter AAA_16 PF13191.6 RLN89242.1 - 3.7e-07 30.7 0.0 0.0065 16.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 RLN89242.1 - 7.1e-07 28.9 0.5 0.068 12.6 0.0 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RLN89242.1 - 7.2e-07 28.9 2.6 0.016 14.9 1.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 RLN89242.1 - 1.3e-06 28.5 0.0 0.18 11.5 0.0 3.7 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN89242.1 - 2.5e-06 27.5 3.0 0.021 14.7 0.4 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 RLN89242.1 - 1.7e-05 25.1 0.0 0.038 14.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 RLN89242.1 - 8.7e-05 21.8 19.1 8.7e-05 21.8 19.1 4.2 2 2 3 5 5 5 2 ABC-2 family transporter protein AAA PF00004.29 RLN89242.1 - 0.00015 22.2 0.1 0.44 11.0 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 RLN89242.1 - 0.00026 20.8 2.1 0.52 10.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 RLN89242.1 - 0.0003 20.4 0.2 0.24 10.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RLN89242.1 - 0.00073 20.1 0.9 0.13 12.8 0.3 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RLN89242.1 - 0.0012 18.2 1.3 0.11 11.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 RLN89242.1 - 0.0015 19.1 0.0 0.54 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 RLN89242.1 - 0.0044 16.8 0.1 0.37 10.5 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 RLN89242.1 - 0.0046 17.3 0.1 0.72 10.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Ploopntkinase3 PF18751.1 RLN89242.1 - 0.0053 16.7 0.4 0.089 12.7 0.0 2.3 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 DUF87 PF01935.17 RLN89242.1 - 0.0074 16.4 3.9 0.22 11.6 0.0 2.6 2 1 0 2 2 2 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 RLN89242.1 - 0.01 15.9 1.6 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 RLN89242.1 - 0.011 15.7 2.5 0.98 9.3 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 RLN89242.1 - 0.018 14.8 0.4 10 5.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 RLN89242.1 - 0.048 13.9 1.0 2.7 8.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 RLN89242.1 - 0.051 13.7 0.1 11 6.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 RLN89242.1 - 0.052 13.5 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea cobW PF02492.19 RLN89242.1 - 0.053 13.1 2.0 3.2 7.3 0.8 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 RLN89242.1 - 0.073 13.1 0.2 2.3 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 RLN89242.1 - 0.1 12.9 0.0 14 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RLN89242.1 - 0.14 12.4 0.7 25 5.1 0.6 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 RLN89242.1 - 0.17 11.9 1.3 7.4 6.6 0.3 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 RLN89242.1 - 0.18 11.5 1.1 6 6.6 0.4 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2178 PF09946.9 RLN89242.1 - 0.27 11.4 2.5 0.98 9.6 0.2 3.0 3 0 0 3 3 2 0 Predicted membrane protein (DUF2178) ATPase PF06745.13 RLN89242.1 - 0.37 10.1 0.9 3.6 6.9 0.0 2.3 2 0 0 2 2 2 0 KaiC ABC_ATPase PF09818.9 RLN89242.1 - 0.4 9.4 2.1 3.7 6.2 0.4 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class PDR_assoc PF08370.11 RLN89242.1 - 4.7 7.0 9.3 7.7 6.3 2.7 3.6 3 0 0 3 3 2 0 Plant PDR ABC transporter associated Uteroglobin PF01099.17 RLN89244.1 - 0.24 11.8 2.6 3.6 8.0 0.1 2.8 2 1 1 3 3 3 0 Uteroglobin family ParcG PF10274.9 RLN89246.1 - 3.6e-26 92.4 0.1 8.8e-26 91.1 0.1 1.5 1 1 0 1 1 1 1 Parkin co-regulated protein Colicin_V PF02674.16 RLN89247.1 - 0.27 11.2 15.5 0.026 14.5 2.0 3.6 3 1 0 3 3 3 0 Colicin V production protein Aa_trans PF01490.18 RLN89248.1 - 1.8e-37 129.0 19.6 2.6e-37 128.5 19.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ATPase_gene1 PF09527.10 RLN89248.1 - 5.3 7.3 10.1 2.5 8.3 4.4 3.3 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Aa_trans PF01490.18 RLN89249.1 - 2e-40 138.8 17.5 3.6e-40 137.9 17.5 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein 60KD_IMP PF02096.20 RLN89250.1 - 9 6.2 10.7 0.23 11.3 0.5 2.5 2 1 0 2 2 2 0 60Kd inner membrane protein ORC2 PF04084.14 RLN89251.1 - 1.3e-27 96.7 0.3 1.3e-25 90.0 0.2 2.1 1 1 1 2 2 2 2 Origin recognition complex subunit 2 DUF2052 PF09747.9 RLN89251.1 - 0.007 16.5 7.4 0.014 15.5 7.4 1.5 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) CNDH2_C PF16858.5 RLN89251.1 - 0.19 11.6 7.9 0.4 10.5 7.9 1.5 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CENP-B_dimeris PF09026.10 RLN89251.1 - 0.25 11.8 6.4 0.74 10.2 6.4 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC27 PF09507.10 RLN89251.1 - 0.83 9.0 15.6 1.3 8.3 15.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FAM176 PF14851.6 RLN89251.1 - 2.3 7.9 15.3 0.67 9.6 12.1 1.7 2 0 0 2 2 2 0 FAM176 family CDC45 PF02724.14 RLN89251.1 - 7 4.8 8.9 11 4.2 8.9 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 RLN89251.1 - 8.2 6.2 11.0 1.8 8.4 7.7 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Aa_trans PF01490.18 RLN89252.1 - 4e-44 150.9 14.1 6e-44 150.4 14.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 RLN89253.1 - 2.6e-42 145.0 13.8 4.6e-42 144.2 13.8 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 RLN89254.1 - 3.3e-43 148.0 14.1 5.3e-43 147.3 14.1 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 RLN89255.1 - 3.5e-44 151.1 18.2 5.1e-44 150.6 18.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein WTF PF03303.13 RLN89255.1 - 0.6 9.8 5.4 0.21 11.3 0.1 2.5 2 1 0 2 2 2 0 WTF protein WD40 PF00400.32 RLN89257.1 - 1e-27 95.8 12.9 1.2e-05 26.0 0.2 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN89257.1 - 1.6e-07 31.5 0.1 0.06 13.7 0.0 4.8 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN89257.1 - 0.005 15.5 1.6 1.5 7.3 0.1 3.3 2 1 2 4 4 4 2 Nucleoporin Nup120/160 ATG16 PF08614.11 RLN89257.1 - 0.006 16.8 27.7 0.13 12.5 19.9 2.3 1 1 2 3 3 3 3 Autophagy protein 16 (ATG16) Ge1_WD40 PF16529.5 RLN89257.1 - 0.0085 15.1 0.4 1.3 7.9 0.0 3.3 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF218 PF02698.17 RLN89257.1 - 0.015 15.4 1.3 0.033 14.2 0.3 2.2 2 0 0 2 2 2 0 DUF218 domain PQQ_3 PF13570.6 RLN89257.1 - 0.033 14.7 2.5 3 8.5 0.0 4.5 6 1 0 6 6 6 0 PQQ-like domain Ribosomal_S21 PF01165.20 RLN89258.1 - 9.3e-09 34.9 0.3 9.3e-09 34.9 0.3 1.4 2 0 0 2 2 2 1 Ribosomal protein S21 Flavi_capsid PF01003.19 RLN89258.1 - 0.0023 17.7 0.3 0.0025 17.6 0.3 1.2 1 0 0 1 1 1 1 Flavivirus capsid protein C Picorna_P3A PF06363.11 RLN89258.1 - 0.049 13.5 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Picornaviridae P3A protein ArsA_ATPase PF02374.15 RLN89259.1 - 1.9e-98 329.4 3.5 1e-77 261.4 0.8 2.0 1 1 1 2 2 2 2 Anion-transporting ATPase CbiA PF01656.23 RLN89259.1 - 4.6e-12 46.1 0.4 1.9e-11 44.1 0.4 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 RLN89259.1 - 6.9e-11 42.4 0.7 5e-09 36.3 0.1 2.6 2 1 1 3 3 3 1 AAA domain Fer4_NifH PF00142.18 RLN89259.1 - 7.1e-06 25.7 0.4 1.9e-05 24.3 0.1 1.8 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 RLN89259.1 - 1.1e-05 25.0 2.9 0.0018 17.8 0.5 2.5 2 1 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 RLN89259.1 - 3.4e-05 23.4 0.4 0.002 17.7 0.0 2.3 2 1 0 2 2 2 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 RLN89259.1 - 0.00017 21.3 0.1 0.00042 20.0 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 RLN89259.1 - 0.0026 17.5 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 RLN89259.1 - 0.0087 15.7 0.0 0.022 14.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 RLN89259.1 - 0.018 14.5 0.2 0.044 13.2 0.0 1.7 2 1 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.22 RLN89259.1 - 0.034 13.3 0.0 0.077 12.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 RLN89259.1 - 0.084 12.1 0.0 0.18 11.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin MeaB PF03308.16 RLN89259.1 - 0.16 10.9 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF572 PF04502.13 RLN89260.1 - 5.6e-06 26.2 16.6 0.00016 21.4 10.7 2.0 1 1 1 2 2 2 2 Family of unknown function (DUF572) DUF2098 PF09871.9 RLN89260.1 - 1 9.7 5.7 0.25 11.7 2.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) Methyltr_RsmB-F PF01189.17 RLN89261.1 - 1.5e-26 93.3 0.9 4.6e-14 52.5 0.2 2.7 3 0 0 3 3 3 2 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 RLN89261.1 - 5.3e-06 26.3 0.1 0.00093 19.0 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN89261.1 - 7.7e-06 26.5 0.4 0.00022 21.9 0.0 3.2 4 0 0 4 4 4 1 Methyltransferase domain FtsJ PF01728.19 RLN89261.1 - 0.00064 19.9 0.0 0.0034 17.5 0.0 2.2 1 1 0 1 1 1 1 FtsJ-like methyltransferase Fibrillarin PF01269.17 RLN89261.1 - 0.0079 15.3 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Fibrillarin Methyltransf_11 PF08241.12 RLN89261.1 - 0.016 15.8 0.1 1.1 9.9 0.0 3.4 3 0 0 3 3 3 0 Methyltransferase domain PCMT PF01135.19 RLN89261.1 - 0.026 14.3 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 RLN89261.1 - 0.06 12.7 0.0 0.19 11.0 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 RLN89261.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 RLN89261.1 - 0.27 12.0 0.8 5 7.9 0.0 3.2 4 0 0 4 4 4 0 Methyltransferase domain Lyase_1 PF00206.20 RLN89262.1 - 8e-86 288.3 0.0 1.1e-85 287.8 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 RLN89262.1 - 1.9e-23 83.0 0.2 4.4e-23 81.8 0.2 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Fe-S_biosyn PF01521.20 RLN89263.1 - 1e-11 45.0 0.0 1.4e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis GAGBD PF16828.5 RLN89264.1 - 0.11 12.5 4.2 0.05 13.7 1.4 1.8 2 0 0 2 2 2 0 GAG-binding domain on surface antigen TPR_12 PF13424.6 RLN89265.1 - 3.1e-37 126.7 16.0 1.8e-15 56.9 3.5 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 RLN89265.1 - 1.7e-34 116.7 21.2 8.7e-10 38.2 0.3 6.7 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 RLN89265.1 - 2.2e-16 58.9 20.0 0.00027 20.6 0.1 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 RLN89265.1 - 1.9e-12 46.4 18.9 0.0031 17.6 0.1 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 RLN89265.1 - 2.1e-12 46.2 22.2 0.072 13.2 0.1 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 RLN89265.1 - 3.4e-10 39.2 15.8 0.0029 17.5 0.2 6.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 RLN89265.1 - 1.3e-08 35.0 10.3 1.8 9.4 0.1 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 RLN89265.1 - 3.7e-07 30.5 7.7 0.00016 22.1 0.8 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF2225 PF09986.9 RLN89265.1 - 1.4e-06 28.2 4.6 0.0011 18.7 0.3 2.2 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_MalT PF17874.1 RLN89265.1 - 1.5e-06 27.8 6.6 0.011 15.1 1.6 3.2 1 1 2 3 3 3 3 MalT-like TPR region TPR_11 PF13414.6 RLN89265.1 - 1.3e-05 24.7 13.6 0.043 13.5 0.1 6.2 6 1 1 7 7 7 2 TPR repeat TPR_14 PF13428.6 RLN89265.1 - 2.4e-05 24.8 18.1 1.9 9.5 0.2 6.0 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN89265.1 - 4.2e-05 23.6 2.1 3.1 8.4 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat SNAP PF14938.6 RLN89265.1 - 0.00049 19.6 12.4 0.00079 18.9 7.0 2.9 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP MIT PF04212.18 RLN89265.1 - 0.036 14.1 12.6 0.28 11.3 2.2 4.3 3 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 RLN89265.1 - 0.056 14.1 20.5 0.12 13.0 0.1 5.9 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 RLN89265.1 - 0.061 14.0 6.1 0.75 10.6 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat RPN6_N PF18055.1 RLN89265.1 - 0.095 13.1 4.1 0.82 10.0 0.8 2.9 1 1 2 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain BRO1 PF03097.18 RLN89265.1 - 0.097 11.5 6.1 0.23 10.2 0.1 2.4 1 1 0 2 2 2 0 BRO1-like domain Abhydrolase_6 PF12697.7 RLN89266.1 - 2.2e-10 41.5 0.0 3.9e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN89266.1 - 0.0014 18.4 0.0 0.0047 16.6 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1057 PF06342.12 RLN89266.1 - 0.061 12.4 0.0 0.16 11.0 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) NdhS PF11623.8 RLN89266.1 - 0.17 11.6 0.2 0.43 10.3 0.2 1.7 1 1 0 1 1 1 0 NAD(P)H dehydrogenase subunit S YojJ PF10372.9 RLN89266.1 - 0.2 11.8 0.5 0.88 9.7 0.0 2.3 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus LT-IIB PF06453.11 RLN89267.1 - 0.069 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) E1-E2_ATPase PF00122.20 RLN89268.1 - 3.9e-25 88.4 0.1 1.1e-24 86.9 0.1 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 RLN89268.1 - 2.9e-16 60.4 0.2 1e-07 32.5 0.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN89268.1 - 0.00054 20.0 0.0 0.0014 18.6 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 RLN89268.1 - 0.001 18.8 0.1 0.58 9.9 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase MULE PF10551.9 RLN89269.1 - 3.9e-05 24.0 0.1 7.5e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain FLYWCH PF04500.16 RLN89269.1 - 0.00022 21.3 2.2 0.0003 20.8 1.0 1.9 2 0 0 2 2 2 1 FLYWCH zinc finger domain Filament PF00038.21 RLN89270.1 - 0.0086 15.7 0.2 0.0086 15.7 0.2 2.8 2 1 1 3 3 3 2 Intermediate filament protein Syntaxin-6_N PF09177.11 RLN89270.1 - 0.063 13.8 8.2 0.76 10.4 3.1 3.0 2 2 0 2 2 2 0 Syntaxin 6, N-terminal Tropomyosin_1 PF12718.7 RLN89270.1 - 0.39 10.9 21.4 0.33 11.1 9.3 3.5 2 1 1 3 3 3 0 Tropomyosin like Leu_zip PF15294.6 RLN89270.1 - 1.7 8.1 13.5 13 5.1 10.9 2.4 2 1 0 2 2 2 0 Leucine zipper Baculo_PEP_C PF04513.12 RLN89270.1 - 4.9 7.2 7.4 3.1 7.8 1.9 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fez1 PF06818.15 RLN89270.1 - 6.1 7.2 19.6 27 5.1 0.1 2.6 1 1 1 2 2 2 0 Fez1 Peptidase_C48 PF02902.19 RLN89274.1 - 1.4e-05 25.1 0.0 1.5e-05 25.0 0.0 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain EF-hand_7 PF13499.6 RLN89275.1 - 1.6e-12 47.7 5.0 2.6e-09 37.4 0.6 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN89275.1 - 9.9e-12 43.8 8.4 8.5e-05 22.2 1.3 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 RLN89275.1 - 1.5e-11 43.0 8.0 5e-06 25.7 1.3 3.8 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 RLN89275.1 - 2.2e-09 37.0 2.9 9.6e-05 22.2 0.4 3.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN89275.1 - 7.2e-06 25.3 10.7 0.0001 21.6 0.9 3.9 4 0 0 4 4 4 1 EF hand RCC1_2 PF13540.6 RLN89275.1 - 1e-05 25.2 1.8 0.00026 20.7 0.6 3.0 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat EF-hand_10 PF14788.6 RLN89275.1 - 0.00032 20.5 0.0 0.0011 18.8 0.0 2.0 1 0 0 1 1 1 1 EF hand SPARC_Ca_bdg PF10591.9 RLN89275.1 - 0.062 13.6 0.1 0.28 11.5 0.0 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region RCC1 PF00415.18 RLN89275.1 - 0.2 12.3 2.5 43 4.8 0.0 3.5 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat Asp-B-Hydro_N PF05279.11 RLN89275.1 - 0.22 11.6 0.0 0.22 11.6 0.0 2.6 3 0 0 3 3 3 0 Aspartyl beta-hydroxylase N-terminal region Ank_5 PF13857.6 RLN89276.1 - 6.4e-41 137.9 20.6 4.7e-06 26.8 0.3 11.5 3 2 9 12 12 12 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN89276.1 - 1.1e-39 134.9 1.5 2.7e-09 37.5 0.0 5.3 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN89276.1 - 3.2e-34 116.9 12.6 1.4e-07 31.9 0.1 8.5 4 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN89276.1 - 1.7e-15 55.5 3.8 3.2 8.6 0.0 11.0 9 2 2 11 11 11 4 Ankyrin repeat Ank PF00023.30 RLN89276.1 - 2.6e-07 30.8 0.0 13 6.4 0.1 7.9 3 1 3 6 6 6 1 Ankyrin repeat TGBp3 PF02495.17 RLN89276.1 - 1.4 8.6 8.2 59 3.4 0.0 5.8 7 0 0 7 7 7 0 Triple gene block 3 Ank_4 PF13637.6 RLN89277.1 - 1.1e-39 134.3 13.7 7.1e-06 26.5 0.0 10.3 7 4 1 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN89277.1 - 2.8e-39 132.6 24.0 2.8e-05 24.3 0.2 14.2 4 2 10 14 14 14 12 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN89277.1 - 4.3e-34 117.0 2.8 4e-08 33.7 0.1 6.4 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN89277.1 - 9.7e-20 68.6 5.8 4.6 8.1 0.0 13.8 14 2 2 16 16 16 3 Ankyrin repeat Ank PF00023.30 RLN89277.1 - 7.8e-05 22.9 0.7 28 5.4 0.0 7.6 3 1 0 3 3 3 0 Ankyrin repeat DUF1843 PF08898.10 RLN89277.1 - 0.00088 19.7 0.0 2.1e+02 2.5 0.0 6.6 8 1 0 8 8 8 0 Domain of unknown function (DUF1843) tRNA_bind PF01588.20 RLN89277.1 - 0.0023 18.0 0.0 0.25 11.5 0.0 3.6 2 1 2 5 5 5 1 Putative tRNA binding domain 2-Hacid_dh_C PF02826.19 RLN89278.1 - 1.4e-50 171.1 0.0 2.2e-50 170.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 RLN89278.1 - 9.8e-25 86.8 0.0 1.5e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 RLN89278.1 - 7.3e-06 25.6 0.0 2e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 ACT domain NAD_binding_2 PF03446.15 RLN89278.1 - 0.00085 19.5 0.8 0.0023 18.1 0.4 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 RLN89278.1 - 0.0021 18.1 0.2 0.0039 17.3 0.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 RLN89278.1 - 0.091 12.6 0.3 0.32 10.9 0.3 2.0 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosomal_L37ae PF01780.19 RLN89279.1 - 6.2e-40 135.2 6.7 7.2e-40 135.0 6.7 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 RLN89279.1 - 0.02 14.9 2.1 0.037 14.0 2.1 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Vps39_2 PF10367.9 RLN89279.1 - 0.039 14.4 0.1 0.048 14.1 0.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Cytochrome_C7 PF14522.6 RLN89279.1 - 0.061 13.3 1.4 0.091 12.8 1.4 1.4 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c zf-BED PF02892.15 RLN89279.1 - 0.09 12.8 8.9 0.13 12.3 0.3 2.7 2 1 1 3 3 3 0 BED zinc finger C1_2 PF03107.16 RLN89279.1 - 1.6 9.1 5.8 0.72 10.2 2.6 2.0 2 1 0 2 2 2 0 C1 domain zf-H2C2_2 PF13465.6 RLN89279.1 - 2.9 8.5 6.7 13 6.4 0.8 2.6 2 1 1 3 3 3 0 Zinc-finger double domain MIB_HERC2 PF06701.13 RLN89280.1 - 5.6e-20 71.4 9.8 1.8e-19 69.8 9.8 1.9 1 0 0 1 1 1 1 Mib_herc2 ZZ PF00569.17 RLN89280.1 - 5.8e-12 45.2 21.1 1.1e-09 38.0 9.5 2.7 2 0 0 2 2 2 2 Zinc finger, ZZ type Ints3 PF10189.9 RLN89281.1 - 8.4e-08 31.8 0.2 1.3e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 Integrator complex subunit 3 Arf PF00025.21 RLN89283.1 - 2.6e-26 92.1 0.2 4.8e-15 55.4 0.0 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 RLN89283.1 - 0.038 13.1 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit SRPRB PF09439.10 RLN89283.1 - 0.14 11.5 0.3 0.83 9.1 0.1 1.9 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit Ank_4 PF13637.6 RLN89285.1 - 2e-36 123.9 2.0 2.1e-09 37.7 0.0 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN89285.1 - 5.1e-36 123.1 4.6 5.7e-13 49.3 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 RLN89285.1 - 7.2e-26 89.5 7.8 1.6e-05 25.1 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 RLN89285.1 - 8.7e-26 89.7 9.2 1.1e-07 31.9 0.2 6.1 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN89285.1 - 1.4e-24 83.4 3.6 0.012 16.1 0.0 6.8 7 0 0 7 7 7 5 Ankyrin repeat Chorion_1 PF01723.16 RLN89285.1 - 0.026 14.5 0.9 1.4 8.8 0.2 2.1 1 1 1 2 2 2 0 Chorion protein TPR_16 PF13432.6 RLN89285.1 - 0.089 13.5 2.1 0.15 12.7 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1949 PF09186.11 RLN89285.1 - 0.15 12.0 1.2 30 4.6 0.0 3.7 5 0 0 5 5 5 0 Domain of unknown function (DUF1949) Atx10homo_assoc PF09759.9 RLN89286.1 - 0.11 12.6 0.0 0.97 9.5 0.0 2.2 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain EF-hand_7 PF13499.6 RLN89287.1 - 3.4e-11 43.4 1.2 2.5e-06 27.8 0.4 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN89287.1 - 1.8e-08 33.4 3.6 0.0063 16.0 0.1 4.0 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 RLN89287.1 - 7.1e-06 25.5 4.0 0.013 15.4 0.1 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.6 RLN89287.1 - 5.3e-05 23.5 0.1 0.00046 20.5 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 RLN89287.1 - 0.032 14.1 2.5 0.48 10.3 0.1 3.3 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.6 RLN89287.1 - 0.046 13.2 2.2 4.4 7.0 0.1 2.8 2 0 0 2 2 2 0 EF hand Biotin_lipoyl PF00364.22 RLN89288.1 - 7.3e-14 51.4 0.3 1.2e-13 50.7 0.3 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 RLN89288.1 - 0.1 13.3 0.0 2.6 8.8 0.0 2.3 1 1 1 2 2 2 0 HlyD family secretion protein Clat_adaptor_s PF01217.20 RLN89289.1 - 8.7e-05 22.5 0.2 0.00029 20.8 0.2 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain FHA PF00498.26 RLN89289.1 - 0.0005 20.4 0.2 0.014 15.7 0.0 2.4 1 1 1 2 2 2 1 FHA domain PIP5K PF01504.18 RLN89290.1 - 4.9e-64 216.2 0.0 2e-63 214.2 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7TM_GPCR_Srsx PF10320.9 RLN89290.1 - 1.5e-05 24.5 3.5 2.5e-05 23.8 3.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_2 PF00002.24 RLN89290.1 - 0.009 15.3 2.2 0.009 15.3 2.2 2.0 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) DoxX_2 PF13564.6 RLN89290.1 - 0.014 15.5 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 DoxX-like family DUF3278 PF11683.8 RLN89290.1 - 0.027 14.6 0.3 0.072 13.2 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) DUF1516 PF07457.11 RLN89290.1 - 5.3 7.3 9.0 0.072 13.3 1.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1516) Glyco_hydro_28 PF00295.17 RLN89294.1 - 0.012 14.8 1.3 0.013 14.6 1.3 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 28 Glyco_hydro_12 PF01670.16 RLN89295.1 - 2.4e-46 158.4 8.9 2.8e-46 158.2 8.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 WD40 PF00400.32 RLN89297.1 - 2.5e-21 75.6 11.4 4.8e-06 27.2 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF4205 PF13898.6 RLN89297.1 - 5.6e-18 65.0 0.1 9.3e-18 64.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) ANAPC4_WD40 PF12894.7 RLN89297.1 - 1.3e-10 41.5 5.2 0.023 15.0 0.0 5.3 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Myb_DNA-binding PF00249.31 RLN89297.1 - 2.8e-06 27.4 1.4 1.1e-05 25.5 1.4 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN89297.1 - 1.5e-05 25.1 0.9 5.3e-05 23.4 0.9 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ge1_WD40 PF16529.5 RLN89297.1 - 0.0011 18.0 0.0 0.39 9.6 0.0 2.8 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein MADF_DNA_bdg PF10545.9 RLN89297.1 - 4.5 7.6 7.3 0.92 9.9 3.2 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like ALMT PF11744.8 RLN89297.1 - 8.9 5.0 8.3 13 4.4 8.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter WD40 PF00400.32 RLN89298.1 - 7.9e-22 77.2 32.3 0.00053 20.7 0.2 10.1 10 1 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN89298.1 - 5.5e-16 58.7 7.6 0.004 17.4 0.1 5.1 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 PF13646.6 RLN89299.1 - 1.2e-15 57.6 5.9 0.00018 21.9 0.2 7.4 7 1 0 8 8 7 3 HEAT repeats HEAT PF02985.22 RLN89299.1 - 1.7e-15 55.8 19.8 0.17 12.2 0.0 11.3 11 0 0 11 11 11 4 HEAT repeat DUF4042 PF13251.6 RLN89299.1 - 3.9e-11 43.0 13.4 8e-11 42.0 0.5 6.3 6 2 1 7 7 7 1 Domain of unknown function (DUF4042) RTP1_C1 PF10363.9 RLN89299.1 - 1.8e-05 24.9 0.0 0.14 12.4 0.0 3.8 4 0 0 4 4 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 RLN89299.1 - 0.00025 20.7 0.0 0.0026 17.4 0.0 2.6 3 0 0 3 3 3 1 Tti2 family Vac14_Fab1_bd PF12755.7 RLN89299.1 - 0.0003 21.3 0.1 19 5.9 0.0 6.3 8 0 0 8 8 7 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 RLN89299.1 - 0.00035 21.0 23.0 0.16 12.5 0.7 9.2 10 2 1 11 11 11 1 HEAT-like repeat HEAT_PBS PF03130.16 RLN89299.1 - 0.00046 20.6 0.5 0.32 11.8 0.0 4.7 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat TAF6_C PF07571.13 RLN89299.1 - 0.054 13.8 0.6 9.3 6.7 0.0 4.3 5 0 0 5 5 4 0 TAF6 C-terminal HEAT repeat domain Sec7_N PF12783.7 RLN89299.1 - 0.12 12.3 0.5 1.8 8.4 0.0 3.3 4 1 1 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal YjgF_endoribonc PF14588.6 RLN89299.1 - 0.12 12.5 0.1 0.31 11.2 0.1 1.6 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease V-ATPase_H_N PF03224.14 RLN89299.1 - 0.25 10.6 2.0 0.39 10.0 0.0 2.2 3 0 0 3 3 3 0 V-ATPase subunit H Arm PF00514.23 RLN89299.1 - 1 9.5 7.1 6.8 6.9 0.4 4.4 5 0 0 5 5 4 0 Armadillo/beta-catenin-like repeat RSB_motif PF16294.5 RLN89300.1 - 2.4e-11 43.8 0.7 2.4e-11 43.8 0.7 3.8 2 1 0 2 2 2 1 RNSP1-SAP18 binding (RSB) motif SAP PF02037.27 RLN89300.1 - 5.8e-05 22.7 0.6 0.00014 21.5 0.6 1.7 1 0 0 1 1 1 1 SAP domain PEPCK_ATP PF01293.20 RLN89301.1 - 1.3e-12 47.2 0.0 1.5e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase NOG1_N PF17835.1 RLN89302.1 - 5.1e-05 23.3 0.1 6.7e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 NOG1 N-terminal helical domain Prefoldin PF02996.17 RLN89303.1 - 0.0024 17.8 2.6 0.0024 17.8 2.6 18.0 13 6 7 22 22 22 1 Prefoldin subunit Uso1_p115_C PF04871.13 RLN89303.1 - 0.0027 18.1 13.3 0.0027 18.1 13.3 14.6 2 2 9 12 12 12 3 Uso1 / p115 like vesicle tethering protein, C terminal region HrpB7 PF09486.10 RLN89303.1 - 0.0047 17.3 24.2 0.0047 17.3 24.2 13.9 7 5 7 14 14 14 2 Bacterial type III secretion protein (HrpB7) DASH_Dad1 PF08649.10 RLN89303.1 - 1.2 9.4 4.1 3.6 7.9 0.8 3.8 3 0 0 3 3 3 0 DASH complex subunit Dad1 Pkinase PF00069.25 RLN89304.1 - 0.0022 17.4 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 RLN89304.1 - 0.024 14.0 0.0 0.059 12.7 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family UPF0242 PF06785.11 RLN89307.1 - 0.0069 16.5 2.2 0.0069 16.5 2.2 3.3 3 1 0 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus BBS2_C PF14782.6 RLN89307.1 - 0.11 11.2 3.2 0.25 10.0 3.2 1.5 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal TMF_DNA_bd PF12329.8 RLN89307.1 - 1.3 9.1 19.5 0.093 12.7 6.5 3.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding COPI_assoc PF08507.10 RLN89308.1 - 2.3e-11 43.9 6.0 3.2e-11 43.4 6.0 1.2 1 0 0 1 1 1 1 COPI associated protein Pkinase PF00069.25 RLN89309.1 - 3.2e-58 197.2 0.0 4.3e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89309.1 - 4.6e-34 117.9 0.0 5.9e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN89309.1 - 1.9e-08 34.0 0.0 4.3e-08 32.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like DEP PF00610.21 RLN89309.1 - 2.4e-05 24.3 0.0 4.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FTA2 PF13095.6 RLN89309.1 - 0.00028 20.6 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RLN89309.1 - 0.0013 18.7 0.1 0.0025 17.8 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN89309.1 - 0.06 12.3 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 RLN89309.1 - 0.074 12.4 0.2 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family baeRF_family5 PF18846.1 RLN89309.1 - 0.094 12.9 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 5 Enolase_C PF00113.22 RLN89310.1 - 4.4e-125 416.8 2.5 5.1e-125 416.6 2.5 1.0 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain MR_MLE_C PF13378.6 RLN89310.1 - 3e-09 36.8 0.0 6.4e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 RLN89310.1 - 4.9e-06 25.9 0.2 8.1e-06 25.2 0.2 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus PCI PF01399.27 RLN89312.1 - 2.5e-13 50.5 0.1 7.1e-13 49.0 0.1 1.9 1 0 0 1 1 1 1 PCI domain SYCP2_ARLD PF18581.1 RLN89312.1 - 0.078 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Synaptonemal complex 2 armadillo-repeat-like domain SET PF00856.28 RLN89316.1 - 5e-12 46.5 0.2 7.5e-10 39.5 0.2 3.3 2 2 0 2 2 2 1 SET domain MULE PF10551.9 RLN89317.1 - 8.9e-10 38.9 0.4 1.6e-09 38.1 0.4 1.4 1 0 0 1 1 1 1 MULE transposase domain IQ PF00612.27 RLN89320.1 - 0.01 15.5 12.6 0.055 13.3 0.1 4.6 4 0 0 4 4 4 0 IQ calmodulin-binding motif Chorion_2 PF03964.15 RLN89321.1 - 0.64 10.9 4.3 0.59 11.0 1.9 2.1 2 0 0 2 2 2 0 Chorion family 2 bZIP_1 PF00170.21 RLN89321.1 - 3 8.0 15.5 4.4 7.5 2.6 2.5 2 0 0 2 2 2 0 bZIP transcription factor Phage_lysis PF03245.13 RLN89322.1 - 0.013 15.6 1.3 0.024 14.7 1.3 1.4 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Herpes_LAMP2 PF06126.11 RLN89322.1 - 0.19 10.3 0.0 0.26 9.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 YabA PF06156.13 RLN89324.1 - 0.95 10.1 8.3 0.11 13.2 0.6 2.4 2 0 0 2 2 2 0 Initiation control protein YabA Baculo_PEP_C PF04513.12 RLN89325.1 - 0.0099 15.9 0.1 0.023 14.8 0.1 1.6 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus CTP_synth_N PF06418.14 RLN89326.1 - 4.2e-124 413.1 0.1 5.4e-124 412.7 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 RLN89326.1 - 4.3e-26 91.9 0.0 7.9e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CbiA PF01656.23 RLN89326.1 - 0.13 12.3 0.0 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 RLN89327.1 - 6.2e-37 127.0 2.0 9e-37 126.4 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN89327.1 - 4.4e-31 108.3 1.6 1.1e-30 106.9 1.6 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN89327.1 - 1.3e-11 44.7 0.5 2e-11 44.2 0.5 1.2 1 0 0 1 1 1 1 KR domain Rho_RNA_bind PF07497.12 RLN89327.1 - 0.074 12.9 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain DUF4158 PF13700.6 RLN89327.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) DUF1776 PF08643.10 RLN89327.1 - 0.17 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) UQ_con PF00179.26 RLN89328.1 - 1.7e-17 63.3 0.0 3.9e-16 59.0 0.0 2.5 1 1 1 2 2 2 1 Ubiquitin-conjugating enzyme Myosin_head PF00063.21 RLN89329.1 - 3e-222 739.6 0.0 3.8e-222 739.2 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 RLN89329.1 - 3.2e-11 42.0 34.2 0.012 15.3 2.6 6.8 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_22 PF13401.6 RLN89329.1 - 0.11 12.8 0.0 0.11 12.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain Use1 PF09753.9 RLN89330.1 - 3.8e-15 56.3 3.7 5e-15 55.9 3.7 1.3 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF4407 PF14362.6 RLN89330.1 - 0.062 12.7 3.4 0.087 12.2 3.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5542 PF17696.1 RLN89330.1 - 0.64 10.2 2.4 14 5.9 0.7 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5542) PGK PF00162.19 RLN89331.1 - 1.7e-156 520.9 0.0 2e-156 520.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PrpR_N PF06506.11 RLN89331.1 - 0.079 12.5 1.4 4.6 6.8 0.1 2.8 2 1 0 2 2 2 0 Propionate catabolism activator HTH_Tnp_Tc5 PF03221.16 RLN89332.1 - 0.065 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain FGGY_N PF00370.21 RLN89333.1 - 0.0067 16.0 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.20 RLN89334.1 - 4.1e-50 170.6 10.1 5.4e-50 170.2 10.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein PIP5K PF01504.18 RLN89336.1 - 5.2e-87 291.5 0.0 8.2e-87 290.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Mito_carr PF00153.27 RLN89336.1 - 1e-61 204.9 3.2 2.1e-22 78.9 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein Sporozoite_P67 PF05642.11 RLN89336.1 - 4.8 5.1 6.9 9.3 4.2 6.9 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AA_permease PF00324.21 RLN89337.1 - 1.5e-16 60.1 35.2 2.3e-16 59.5 35.2 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 RLN89337.1 - 2.5e-16 59.6 39.5 3.3e-16 59.2 39.5 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN89338.1 - 1.6e-19 69.9 37.5 2.1e-19 69.5 37.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 RLN89338.1 - 4.3e-18 65.4 43.5 5.5e-18 65.0 43.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2244 PF10003.9 RLN89338.1 - 0.056 13.1 0.3 0.056 13.1 0.3 3.8 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) TRAM1 PF08390.11 RLN89338.1 - 0.058 13.1 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 TRAM1-like protein AA_permease_2 PF13520.6 RLN89339.1 - 1.3e-10 40.7 37.9 1.6e-10 40.4 37.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN89339.1 - 3.2e-10 39.2 32.2 4.9e-10 38.6 32.2 1.2 1 0 0 1 1 1 1 Amino acid permease SEP PF08059.13 RLN89340.1 - 1.1e-25 90.0 0.0 1.7e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 RLN89340.1 - 7.9e-05 22.8 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 UBX domain RRM_1 PF00076.22 RLN89341.1 - 4.6e-20 71.2 0.0 6e-11 42.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RLN89341.1 - 2.7e-08 33.5 0.0 2.1e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RLN89341.1 - 1.4e-07 31.3 0.0 0.0014 18.4 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif TMEM82 PF15816.5 RLN89342.1 - 0.18 10.7 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 82 DUF98 PF01947.16 RLN89343.1 - 9.4e-39 132.7 0.0 1.2e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 p-hydroxybenzoic acid synthase Ribosomal_L34 PF00468.17 RLN89344.1 - 8.8e-16 57.6 11.0 1.3e-15 57.0 11.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 tRNA-synt_1c PF00749.21 RLN89346.1 - 1.9e-96 322.7 0.0 3.4e-96 321.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 RLN89346.1 - 6.2e-34 117.4 0.0 1.5e-33 116.1 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Gal11_ABD1 PF18535.1 RLN89346.1 - 0.071 13.2 0.0 5.3 7.2 0.0 3.0 3 0 0 3 3 3 0 Gal11 activator-binding domain (ABD1) DUF3868 PF12984.7 RLN89346.1 - 0.2 11.5 0.3 0.35 10.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3868) Strep_SA_rep PF06696.11 RLN89347.1 - 0.0052 16.7 0.6 3.8 7.6 0.1 2.6 2 0 0 2 2 2 2 Streptococcal surface antigen repeat Nucleoporin_FG2 PF15967.5 RLN89347.1 - 0.01 14.4 79.6 0.048 12.2 18.8 3.8 1 1 1 2 2 2 0 Nucleoporin FG repeated region COG5 PF10392.9 RLN89347.1 - 0.37 11.0 3.0 0.18 12.0 0.7 1.6 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Nucleoporin_FG PF13634.6 RLN89347.1 - 1.8 9.4 67.2 0.25 12.2 23.7 3.8 2 2 1 3 3 3 0 Nucleoporin FG repeat region Cellulase PF00150.18 RLN89348.1 - 1.2e-10 41.3 0.0 1.8e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) UPF0183 PF03676.14 RLN89350.1 - 2.1e-60 205.1 0.0 1.9e-40 139.4 0.0 3.0 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0183) Gar1 PF04410.14 RLN89351.1 - 2.5e-33 115.0 0.0 6.2e-33 113.8 0.0 1.6 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region DNA_pol_phi PF04931.13 RLN89351.1 - 2 6.4 12.0 3.2 5.8 12.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Sod_Fe_C PF02777.18 RLN89353.1 - 4.8e-41 139.1 0.2 1.8e-40 137.2 0.0 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 RLN89353.1 - 2.7e-27 95.0 2.2 4.9e-27 94.2 2.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DDE_1 PF03184.19 RLN89354.1 - 8.7e-29 100.4 0.0 1.2e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_ABP1_N PF18107.1 RLN89354.1 - 1e-05 25.2 1.8 4.7e-05 23.0 0.0 2.7 3 0 0 3 3 3 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 RLN89354.1 - 1e-05 25.5 0.8 2.6e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Myb_DNA-binding PF00249.31 RLN89355.1 - 4.4e-07 30.0 0.1 9.3e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SR-25 PF10500.9 RLN89355.1 - 0.19 11.3 7.5 0.29 10.7 7.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAM199X PF15814.5 RLN89355.1 - 2.2 7.2 9.7 3.2 6.7 9.7 1.2 1 0 0 1 1 1 0 Protein family FAM199X DUF2009 PF09418.10 RLN89356.1 - 1.1e-200 667.5 0.0 1.3e-200 667.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 RLN89356.1 - 0.0006 19.9 5.6 0.0011 19.1 5.6 1.4 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 RLN89356.1 - 0.11 12.7 4.9 0.25 11.6 4.9 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Laminin_EGF PF00053.24 RLN89356.1 - 0.24 11.6 4.3 0.47 10.6 4.3 1.4 1 0 0 1 1 1 0 Laminin EGF domain Laminin_G_3 PF13385.6 RLN89357.1 - 1.1e-13 51.6 0.0 2.7e-13 50.3 0.0 1.6 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily F-box_4 PF15966.5 RLN89357.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 RLN89357.1 - 0.13 12.2 0.5 0.46 10.4 0.5 2.0 1 0 0 1 1 1 0 F-box-like PseudoU_synth_2 PF00849.22 RLN89359.1 - 1.1e-07 32.0 4.0 3.1e-07 30.6 2.5 2.4 2 1 0 2 2 2 1 RNA pseudouridylate synthase HMG_box_2 PF09011.10 RLN89359.1 - 0.00057 20.4 0.2 0.002 18.7 0.2 1.9 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 RLN89359.1 - 0.0041 17.5 0.2 0.013 15.9 0.2 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box TPR_12 PF13424.6 RLN89360.1 - 1.4e-14 54.1 3.5 1.5e-09 38.0 0.2 4.3 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN89360.1 - 0.00018 21.4 0.7 0.0022 18.1 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN89360.1 - 0.00039 20.2 3.3 0.11 12.4 0.2 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN89360.1 - 0.00046 19.9 0.7 0.024 14.4 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 RLN89360.1 - 0.0012 18.8 1.1 0.027 14.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat FKS1_dom1 PF14288.6 RLN89360.1 - 0.062 13.6 0.1 0.23 11.8 0.0 1.8 2 0 0 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 TPR_14 PF13428.6 RLN89360.1 - 0.58 11.1 5.6 12 7.1 0.0 4.2 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN89360.1 - 1.5 9.6 4.9 4.3 8.2 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 RLN89361.1 - 4e-27 94.1 5.7 6.3e-15 55.1 0.9 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN89361.1 - 1.7e-22 79.4 0.2 2.8e-11 43.5 0.0 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 RLN89361.1 - 0.0027 18.0 0.9 1.7 9.0 0.1 2.1 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like APOC4 PF15119.6 RLN89361.1 - 0.012 15.8 0.6 4.2 7.7 0.0 2.3 1 1 1 2 2 2 0 Apolipoprotein C4 Myb_DNA-bind_4 PF13837.6 RLN89361.1 - 0.015 15.6 2.8 3.8 7.9 0.3 2.4 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 RLN89362.1 - 2.2e-38 132.1 1.7 2.3e-22 79.6 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89362.1 - 1.5e-18 67.1 0.0 1.1e-12 47.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase RWD PF05773.22 RLN89362.1 - 1.9e-16 60.4 0.7 1.4e-14 54.4 0.0 3.1 2 1 0 2 2 2 1 RWD domain Kinase-like PF14531.6 RLN89362.1 - 0.0013 18.2 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 RLN89362.1 - 0.0049 16.5 3.5 0.045 13.4 0.0 2.8 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RLN89362.1 - 0.0086 16.0 2.4 0.013 15.4 0.0 2.4 3 0 0 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 RLN89362.1 - 0.16 11.0 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 TFIIA PF03153.13 RLN89362.1 - 0.5 10.3 19.4 0.033 14.2 7.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit GFO_IDH_MocA PF01408.22 RLN89363.1 - 3e-07 31.3 0.0 3.4e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold PDEase_I PF00233.19 RLN89364.1 - 8.8e-67 225.3 0.0 1.5e-66 224.5 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase SLATT_1 PF18181.1 RLN89364.1 - 0.11 12.5 3.6 6.4 6.7 0.7 3.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 ResB PF05140.14 RLN89364.1 - 0.27 9.9 3.3 0.085 11.6 0.5 1.6 2 0 0 2 2 2 0 ResB-like family FYVE PF01363.21 RLN89365.1 - 5.5e-07 29.6 3.8 1.6e-06 28.2 3.8 1.8 1 0 0 1 1 1 1 FYVE zinc finger Prok-RING_2 PF14445.6 RLN89365.1 - 2.6 8.3 8.9 30 4.9 4.7 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Ank_5 PF13857.6 RLN89366.1 - 0.00083 19.6 0.1 0.0016 18.7 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN89366.1 - 0.012 16.2 0.0 0.037 14.6 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) TetR_C_8 PF14278.6 RLN89366.1 - 0.061 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region DHHC PF01529.20 RLN89366.1 - 0.81 9.8 8.4 1.5 8.9 8.4 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase Topoisom_I PF01028.20 RLN89367.1 - 3.3e-90 301.4 0.3 3.3e-90 301.4 0.3 1.7 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 RLN89367.1 - 8.1e-84 280.4 0.1 2e-83 279.1 0.1 1.7 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 RLN89367.1 - 6.8e-18 64.4 0.2 3.6e-17 62.1 0.2 2.3 1 0 0 1 1 1 1 C-terminal topoisomerase domain GHMP_kinases_N PF00288.26 RLN89368.1 - 2.3e-11 43.7 0.1 2.3e-11 43.7 0.1 2.9 2 1 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 RLN89368.1 - 9.9e-08 32.3 0.1 3.4e-07 30.5 0.1 2.0 1 0 0 1 1 1 1 GHMP kinases C terminal FIST PF08495.10 RLN89369.1 - 2.3e-23 83.1 0.4 9.2e-23 81.1 0.1 2.3 2 0 0 2 2 2 1 FIST N domain FYVE PF01363.21 RLN89369.1 - 1.4e-11 44.3 9.2 3.3e-11 43.1 9.2 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN89369.1 - 0.0035 17.5 5.5 0.011 15.9 5.5 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger FIST_C PF10442.9 RLN89369.1 - 0.0088 16.0 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 FIST C domain Med3 PF11593.8 RLN89371.1 - 1.5 7.9 18.7 2 7.5 18.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal VPS9 PF02204.18 RLN89372.1 - 1.3e-14 54.3 0.0 5.7e-14 52.2 0.0 2.1 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Cwf_Cwc_15 PF04889.12 RLN89372.1 - 0.011 15.5 6.6 0.018 14.8 6.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ABC_tran PF00005.27 RLN89373.1 - 3e-15 56.9 0.1 7.4e-15 55.7 0.0 1.7 2 0 0 2 2 2 1 ABC transporter ABC2_membrane PF01061.24 RLN89373.1 - 0.0022 17.4 1.3 0.0031 16.9 1.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_16 PF13191.6 RLN89373.1 - 0.0084 16.5 0.0 0.03 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RLN89373.1 - 0.022 15.0 0.0 0.11 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 RLN89373.1 - 0.061 12.8 0.1 11 5.4 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 RLN89373.1 - 0.079 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RLN89373.1 - 0.088 12.1 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Glyco_hydro_72 PF03198.14 RLN89374.1 - 3.1e-09 36.5 0.0 3.6e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Glucanosyltransferase PX PF00787.24 RLN89378.1 - 5.8e-20 71.4 0.0 1.8e-09 37.6 0.0 2.2 2 0 0 2 2 2 2 PX domain DUF630 PF04783.12 RLN89378.1 - 0.19 11.9 0.5 23 5.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF630) PX PF00787.24 RLN89379.1 - 1.4e-08 34.7 0.0 2.2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 PX domain DUF916 PF06030.12 RLN89379.1 - 0.012 15.6 0.3 0.027 14.5 0.2 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF916) PX PF00787.24 RLN89380.1 - 1.3e-11 44.5 0.0 1.7e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 PX domain RhoGEF PF00621.20 RLN89382.1 - 1.7e-23 83.8 0.0 2.4e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain HlyE PF06109.13 RLN89382.1 - 0.22 10.8 0.0 0.34 10.2 0.0 1.1 1 0 0 1 1 1 0 Haemolysin E (HlyE) PX PF00787.24 RLN89384.1 - 9.8e-08 32.0 0.0 1.7e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 PX domain ArfGap PF01412.18 RLN89386.1 - 1.1e-16 61.0 2.9 1.8e-16 60.3 2.9 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf OrfB_Zn_ribbon PF07282.11 RLN89386.1 - 0.2 11.6 4.2 0.47 10.4 4.2 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain HTH_23 PF13384.6 RLN89387.1 - 0.00038 20.2 0.8 0.00095 18.9 0.8 1.8 1 1 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_1 PF01527.20 RLN89387.1 - 0.0066 16.7 0.2 0.013 15.8 0.2 1.4 1 0 0 1 1 1 1 Transposase CENP-B_N PF04218.13 RLN89387.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 RLN89387.1 - 0.02 14.7 0.1 0.043 13.6 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 RLN89387.1 - 0.038 14.1 2.3 0.14 12.3 2.3 2.0 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 RLN89387.1 - 0.05 13.7 0.1 0.31 11.2 0.0 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain of resolvase HECW_N PF16562.5 RLN89387.1 - 0.19 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 HTH_29 PF13551.6 RLN89387.1 - 0.44 10.6 4.1 3 7.9 1.8 2.9 2 1 0 2 2 2 0 Winged helix-turn helix FHA PF00498.26 RLN89388.1 - 6.9e-11 42.3 0.0 1.2e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RLN89388.1 - 2.1e-05 24.8 0.0 7e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain CM_2 PF01817.21 RLN89388.1 - 0.092 13.1 0.2 0.2 12.1 0.2 1.6 1 0 0 1 1 1 0 Chorismate mutase type II CcmD PF04995.14 RLN89388.1 - 0.61 10.2 3.4 1.4 9.0 3.4 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Nucleo_P87 PF07267.11 RLN89388.1 - 7.5 5.3 13.2 17 4.1 13.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MMR_HSR1 PF01926.23 RLN89389.1 - 7.1e-17 61.5 0.0 5.1e-14 52.3 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN89389.1 - 2.3e-07 30.5 0.0 2.4e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RLN89389.1 - 1.9e-06 27.9 0.1 0.067 13.1 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase AIG1 PF04548.16 RLN89389.1 - 0.00023 20.5 0.0 0.0004 19.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 RLN89389.1 - 0.00054 19.6 0.1 0.066 12.7 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 RLN89389.1 - 0.045 13.8 0.9 0.49 10.4 0.4 2.6 2 1 1 3 3 3 0 Dynamin family AAA_16 PF13191.6 RLN89389.1 - 0.98 9.8 0.0 0.98 9.8 0.0 3.7 3 2 0 3 3 3 0 AAA ATPase domain PX PF00787.24 RLN89390.1 - 8.7e-09 35.4 0.1 2e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 PX domain PX PF00787.24 RLN89391.1 - 1.2e-10 41.4 0.0 2.4e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 PX domain LT-IIB PF06453.11 RLN89391.1 - 0.1 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) SAP130_C PF16014.5 RLN89392.1 - 1.9 7.5 8.2 2.5 7.1 8.2 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus FSH1 PF03959.13 RLN89393.1 - 1e-37 129.9 0.0 1.1e-37 129.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 RLN89393.1 - 0.0061 16.4 0.0 0.0082 16.0 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 RLN89393.1 - 0.027 14.4 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Invasin_D3 PF09134.10 RLN89394.1 - 0.03 14.6 3.1 0.058 13.7 2.4 1.9 2 0 0 2 2 2 0 Invasin, domain 3 AI-2E_transport PF01594.16 RLN89396.1 - 0.2 10.8 0.7 7.9 5.5 0.3 2.2 2 0 0 2 2 2 0 AI-2E family transporter VanW PF04294.13 RLN89397.1 - 0.07 12.8 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 VanW like protein ENTH PF01417.20 RLN89398.1 - 4e-09 36.6 0.0 7.3e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 ENTH domain TPR_2 PF07719.17 RLN89399.1 - 2.3e-11 42.9 2.7 0.0078 16.2 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 RLN89399.1 - 3.4e-11 42.5 0.2 0.0033 17.2 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN89399.1 - 9.5e-06 25.8 8.8 0.00094 19.4 1.1 4.3 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN89399.1 - 0.0018 18.3 0.3 15 6.1 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN89399.1 - 0.0018 18.1 4.7 0.057 13.5 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN89399.1 - 0.003 18.1 2.1 26 5.7 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN89399.1 - 0.0034 17.8 12.0 0.022 15.3 0.0 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN89399.1 - 0.0091 16.1 0.6 1.9 8.7 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN89399.1 - 0.03 14.4 1.1 2.9 8.0 0.0 3.4 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 RLN89399.1 - 0.038 14.2 2.0 0.19 12.0 1.4 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TB2_DP1_HVA22 PF03134.19 RLN89400.1 - 3.3e-30 103.8 8.2 4.9e-30 103.3 8.2 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Nrap_D5 PF17406.2 RLN89401.1 - 4.7e-43 146.7 2.1 8.3e-42 142.7 0.4 2.5 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D3 PF17404.2 RLN89401.1 - 2e-42 145.0 0.2 3.7e-42 144.1 0.2 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D4 PF17405.2 RLN89401.1 - 1.4e-41 142.2 0.0 2.5e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 RLN89401.1 - 3e-37 128.0 0.0 6.7e-37 126.9 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 RLN89401.1 - 8.5e-35 119.8 1.0 2.2e-34 118.4 0.6 1.9 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D6 PF17407.2 RLN89401.1 - 6.8e-23 81.4 0.0 1.3e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 6 Pro_isomerase PF00160.21 RLN89402.1 - 1.3e-39 136.0 0.0 1.8e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 RLN89402.1 - 1.1e-08 34.7 0.0 2e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA-synt_1 PF00133.22 RLN89403.1 - 2.4e-118 396.0 0.0 2.2e-73 247.5 0.0 4.7 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 RLN89403.1 - 4.7e-25 88.3 0.1 1.7e-24 86.5 0.1 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 RLN89403.1 - 4.8e-09 35.4 0.1 8.4e-06 24.8 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 RLN89403.1 - 1.7e-06 27.6 0.2 0.024 14.2 0.1 3.0 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 RLN89403.1 - 0.092 12.1 0.0 0.55 9.5 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1c PF00749.21 RLN89403.1 - 0.16 10.9 0.1 0.34 9.8 0.1 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain UQ_con PF00179.26 RLN89404.1 - 3.4e-21 75.3 0.2 5.2e-21 74.8 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UQ_con PF00179.26 RLN89405.1 - 1.5e-20 73.3 0.0 2.1e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CBM_35 PF16990.5 RLN89405.1 - 0.097 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding module (family 35) RWD PF05773.22 RLN89405.1 - 0.17 12.2 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 RWD domain DUF1674 PF07896.12 RLN89406.1 - 3.1e-10 40.4 3.6 6.8e-10 39.3 3.6 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) NTPase_P4 PF11602.8 RLN89406.1 - 0.032 13.5 0.2 0.04 13.1 0.2 1.1 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 FragX_IP PF05994.11 RLN89407.1 - 2.3e-109 366.7 3.3 6.3e-88 295.8 2.2 2.3 1 1 0 2 2 2 2 Cytoplasmic Fragile-X interacting family WASH-7_N PF14745.6 RLN89407.1 - 0.0014 17.3 0.5 0.0034 16.0 0.5 1.6 1 0 0 1 1 1 1 WASH complex subunit 7, N-terminal DUF1394 PF07159.12 RLN89407.1 - 0.023 14.0 0.9 0.044 13.1 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1394) DNA_pol_B PF00136.21 RLN89408.1 - 9.7e-112 374.0 0.0 1.4e-111 373.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 RLN89408.1 - 3.9e-42 144.1 1.1 8.3e-42 143.0 1.1 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 RLN89408.1 - 1.5e-27 96.7 0.0 2.7e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 RLN89408.1 - 6.4e-16 58.2 4.4 6.4e-16 58.2 4.4 2.5 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 RLN89408.1 - 0.037 12.9 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral TGase_elicitor PF16683.5 RLN89410.1 - 1.8e-05 23.7 0.0 2.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Transglutaminase elicitor DUF2785 PF10978.8 RLN89411.1 - 0.067 13.0 3.3 2.3 8.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2785) WD40 PF00400.32 RLN89411.1 - 0.12 13.3 0.1 2.2 9.3 0.0 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 RLN89412.1 - 1.3e-79 267.1 0.0 5.3e-45 153.7 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN89412.1 - 2.3e-76 256.7 0.0 1.4e-49 168.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 RLN89412.1 - 0.0012 18.8 1.0 0.061 13.2 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family FAM176 PF14851.6 RLN89412.1 - 0.043 13.5 0.1 0.1 12.2 0.1 1.7 1 0 0 1 1 1 0 FAM176 family Pkinase_fungal PF17667.1 RLN89412.1 - 0.06 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Cadherin_C_2 PF16492.5 RLN89412.1 - 0.11 13.3 0.0 1 10.1 0.0 2.4 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal SR-25 PF10500.9 RLN89413.1 - 2.1 7.9 21.6 0.038 13.6 13.5 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RWP-RK PF02042.15 RLN89416.1 - 6.2e-12 45.3 0.0 1.2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain HTH_6 PF01418.17 RLN89416.1 - 0.011 15.7 0.3 0.034 14.1 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family NUMOD1 PF07453.13 RLN89416.1 - 0.2 12.0 0.0 0.47 10.8 0.0 1.6 1 0 0 1 1 1 0 NUMOD1 domain HTH_8 PF02954.19 RLN89416.1 - 0.43 10.4 2.0 0.46 10.3 0.0 2.0 2 1 1 3 3 3 0 Bacterial regulatory protein, Fis family bZIP_1 PF00170.21 RLN89417.1 - 0.12 12.5 11.6 0.045 13.9 5.5 2.2 2 0 0 2 2 2 0 bZIP transcription factor TMEM192 PF14802.6 RLN89417.1 - 0.19 10.8 0.5 0.28 10.2 0.5 1.2 1 0 0 1 1 1 0 TMEM192 family bZIP_2 PF07716.15 RLN89417.1 - 0.24 11.5 15.6 0.036 14.1 5.8 2.2 2 0 0 2 2 2 0 Basic region leucine zipper fn3 PF00041.21 RLN89418.1 - 6.8e-72 237.8 11.5 1.3e-08 35.1 0.0 16.3 14 1 2 16 16 16 12 Fibronectin type III domain Calx-beta PF03160.14 RLN89418.1 - 2.1e-25 88.8 2.7 1.2e-12 47.9 0.2 4.3 4 0 0 4 4 4 3 Calx-beta domain DUF4959 PF16323.5 RLN89418.1 - 0.00014 22.1 1.5 2.2 8.7 0.0 5.3 4 0 0 4 4 4 1 Domain of unknown function (DUF4959) Pur_ac_phosph_N PF16656.5 RLN89418.1 - 0.021 15.4 24.4 4.1 8.0 0.1 10.7 11 1 0 11 11 11 0 Purple acid Phosphatase, N-terminal domain Cytochrom_B_C PF00032.17 RLN89418.1 - 0.086 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD DUF4957 PF16318.5 RLN89419.1 - 0.022 14.7 21.1 0.07 13.1 1.6 6.8 6 1 2 8 8 8 0 Domain of unknown function (DUF4957) SMC_N PF02463.19 RLN89420.1 - 4.8e-58 196.2 41.7 6.3e-57 192.5 41.7 3.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 RLN89420.1 - 1.3e-20 73.8 0.1 7.8e-20 71.3 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 RLN89420.1 - 3e-13 50.3 3.6 9.3e-06 25.7 0.1 2.9 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RLN89420.1 - 3.7e-12 47.2 13.9 3.7e-12 47.2 13.9 6.7 3 2 1 4 4 4 1 AAA domain AAA_15 PF13175.6 RLN89420.1 - 0.0001 22.1 26.3 0.0001 22.1 26.3 4.4 2 2 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 RLN89420.1 - 0.00012 21.8 0.0 0.00028 20.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain LacI PF00356.21 RLN89420.1 - 0.00014 21.6 3.1 3.5 7.5 0.0 4.5 3 1 1 4 4 4 3 Bacterial regulatory proteins, lacI family EzrA PF06160.12 RLN89420.1 - 3 5.9 94.3 0.12 10.6 23.9 5.8 3 2 2 5 5 5 0 Septation ring formation regulator, EzrA DUF4570 PF15134.6 RLN89421.1 - 0.0089 16.0 7.0 0.0089 16.0 7.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4570) DUF3666 PF12408.8 RLN89421.1 - 0.088 12.0 0.1 0.73 9.1 0.0 2.5 2 1 0 2 2 2 0 Ribose-5-phosphate isomerase Atg14 PF10186.9 RLN89421.1 - 0.9 8.6 10.2 1.1 8.2 10.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 COG2 PF06148.11 RLN89421.1 - 1.6 8.8 9.1 1.9 8.6 1.9 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Exonuc_VII_L PF02601.15 RLN89421.1 - 2.9 7.4 11.5 4.2 6.9 11.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1104 PF06518.11 RLN89421.1 - 4 7.9 8.8 15 6.1 1.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1104) MRP-S26 PF14943.6 RLN89421.1 - 6 6.8 14.3 2.8 7.8 11.8 1.7 1 1 0 1 1 1 0 Mitochondrial ribosome subunit S26 CENP-H PF05837.12 RLN89421.1 - 6.2 7.3 15.0 0.81 10.1 8.5 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) SecY PF00344.20 RLN89423.1 - 1.6e-73 247.7 16.1 2.1e-73 247.3 16.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 RLN89423.1 - 1.3e-18 66.5 1.8 1.3e-18 66.5 0.1 2.0 2 0 0 2 2 2 1 Plug domain of Sec61p Not3 PF04065.15 RLN89424.1 - 0.092 12.2 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Alk_phosphatase PF00245.20 RLN89425.1 - 6.3e-80 269.2 5.5 8.1e-80 268.8 5.5 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 RLN89425.1 - 0.00019 20.9 0.0 0.00037 19.9 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF659 PF04937.15 RLN89426.1 - 5.2e-24 84.8 0.1 8.6e-24 84.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 RLN89426.1 - 1.4e-06 28.0 0.1 4.3e-05 23.2 0.1 2.8 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 RLN89426.1 - 1.8e-06 27.9 4.5 1.8e-06 27.9 4.5 1.8 2 0 0 2 2 2 1 BED zinc finger zf-RING_10 PF16685.5 RLN89426.1 - 0.11 12.6 3.9 0.13 12.4 2.4 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 Methyltransf_3 PF01596.17 RLN89427.1 - 2.6e-49 167.3 0.0 3.3e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 RLN89427.1 - 3.4e-10 40.9 0.0 6.1e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 RLN89427.1 - 9.2e-06 25.5 0.0 1.5e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 RLN89427.1 - 5.6e-05 23.8 0.1 0.00017 22.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN89427.1 - 0.0096 15.7 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN89427.1 - 0.015 16.1 0.0 0.047 14.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 RLN89427.1 - 0.027 14.3 0.0 0.06 13.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 RLN89427.1 - 0.078 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ubie_methyltran PF01209.18 RLN89427.1 - 0.18 11.1 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family IRK_C PF17655.1 RLN89428.1 - 1.3e-11 44.4 0.0 1.5e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain Paramyxo_P_V_N PF13825.6 RLN89428.1 - 0.0057 16.1 0.3 0.0066 15.9 0.3 1.1 1 0 0 1 1 1 1 Paramyxovirus structural protein V/P N-terminus La PF05383.17 RLN89429.1 - 2.9e-14 52.8 0.0 4.2e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 La domain Peptidase_C15 PF01470.17 RLN89429.1 - 3.5e-14 53.5 0.0 1e-13 51.9 0.0 1.7 1 1 0 1 1 1 1 Pyroglutamyl peptidase RRM_1 PF00076.22 RLN89429.1 - 0.0069 16.2 0.0 0.019 14.7 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF883 PF05957.13 RLN89429.1 - 1.8 9.2 7.0 3.4 8.4 4.6 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) GYF_2 PF14237.6 RLN89430.1 - 0.052 13.4 0.0 0.16 11.8 0.0 1.9 1 0 0 1 1 1 0 GYF domain 2 FdsD PF11390.8 RLN89430.1 - 0.18 12.1 0.4 1.8 8.9 0.0 2.8 4 0 0 4 4 4 0 NADH-dependant formate dehydrogenase delta subunit FdsD IRK_C PF17655.1 RLN89431.1 - 7.5e-08 32.2 0.0 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain Ion_trans_2 PF07885.16 RLN89431.1 - 4.6e-07 29.7 3.2 1.1e-06 28.5 3.2 1.7 1 0 0 1 1 1 1 Ion channel DUF1279 PF06916.13 RLN89431.1 - 0.0046 17.5 0.1 0.037 14.6 0.0 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF1279) Pkinase PF00069.25 RLN89432.1 - 3.1e-29 102.2 0.0 3.7e-24 85.5 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Peptidase_C48 PF02902.19 RLN89432.1 - 7.8e-13 48.8 0.0 1.4e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Pkinase_Tyr PF07714.17 RLN89432.1 - 4.2e-12 45.9 0.0 9.6e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HRDC PF00570.23 RLN89432.1 - 3e-09 36.7 0.0 8.3e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 HRDC domain CN_hydrolase PF00795.22 RLN89432.1 - 7.3e-08 32.1 0.0 3e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase KIX_2 PF16987.5 RLN89432.1 - 6e-06 26.2 0.2 2.3e-05 24.3 0.1 2.0 2 0 0 2 2 2 1 KIX domain Filament PF00038.21 RLN89432.1 - 0.038 13.6 1.2 0.076 12.6 1.2 1.4 1 0 0 1 1 1 0 Intermediate filament protein Proteasom_Rpn13 PF04683.13 RLN89433.1 - 1.6e-21 76.6 0.0 2.6e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor UIM PF02809.20 RLN89433.1 - 0.47 10.5 3.9 1.2 9.2 3.9 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif FAM199X PF15814.5 RLN89433.1 - 1 8.3 4.6 1.8 7.5 4.6 1.3 1 0 0 1 1 1 0 Protein family FAM199X Tugs PF17840.1 RLN89434.1 - 0.053 13.7 0.1 0.19 12.0 0.1 1.9 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain Cation_efflux PF01545.21 RLN89435.1 - 1.3e-46 158.9 3.8 1.3e-46 158.9 3.8 2.4 3 0 0 3 3 3 1 Cation efflux family AAA PF00004.29 RLN89436.1 - 4.5e-34 117.7 0.0 6.8e-23 81.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN89436.1 - 2.9e-09 37.3 0.2 0.0013 19.0 0.1 3.3 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 RLN89436.1 - 3.1e-08 34.2 9.7 0.00048 20.5 0.2 4.3 3 2 1 4 4 3 2 AAA ATPase domain NACHT PF05729.12 RLN89436.1 - 2.5e-06 27.5 0.3 0.06 13.3 0.1 2.9 2 1 0 2 2 2 2 NACHT domain AAA_14 PF13173.6 RLN89436.1 - 5.6e-06 26.4 0.0 0.14 12.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 RLN89436.1 - 2.1e-05 24.2 1.9 0.0033 17.2 0.5 2.5 2 0 0 2 2 2 1 AAA+ lid domain AAA_7 PF12775.7 RLN89436.1 - 0.0001 21.9 0.0 0.015 14.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 RLN89436.1 - 0.00018 22.1 0.0 1.1 9.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 RLN89436.1 - 0.00032 20.8 0.0 0.02 15.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 RLN89436.1 - 0.00084 19.7 0.0 0.094 13.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_29 PF13555.6 RLN89436.1 - 0.001 18.7 0.3 2 8.2 0.0 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 RLN89436.1 - 0.0011 19.1 0.1 0.2 11.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RLN89436.1 - 0.0013 18.5 0.0 0.074 12.8 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.14 RLN89436.1 - 0.0018 18.3 0.2 0.019 15.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 RLN89436.1 - 0.0019 18.7 0.1 0.25 11.8 0.1 2.6 2 0 0 2 2 2 1 ABC transporter Mg_chelatase PF01078.21 RLN89436.1 - 0.0022 17.4 0.4 0.33 10.3 0.1 2.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 RLN89436.1 - 0.0024 17.2 0.4 8.5 5.6 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin Rad17 PF03215.15 RLN89436.1 - 0.0027 17.7 0.0 0.023 14.6 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 RLN89436.1 - 0.003 17.1 0.8 1.1 8.8 0.0 3.3 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 RLN89436.1 - 0.0045 16.7 0.0 1.1 8.9 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain TsaE PF02367.17 RLN89436.1 - 0.0056 16.7 0.0 0.039 14.0 0.0 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 RLN89436.1 - 0.012 14.9 0.3 0.11 11.8 0.0 2.2 2 0 0 2 2 2 0 KaiC DUF815 PF05673.13 RLN89436.1 - 0.019 14.1 0.3 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) T2SSE PF00437.20 RLN89436.1 - 0.022 13.9 0.1 0.8 8.7 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_10 PF12846.7 RLN89436.1 - 0.025 13.5 1.5 0.69 8.8 0.0 2.5 2 1 1 3 3 3 0 AAA-like domain Viral_helicase1 PF01443.18 RLN89436.1 - 0.031 14.0 0.0 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 RLN89436.1 - 0.031 14.2 0.0 0.81 9.6 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 RLN89436.1 - 0.033 14.4 0.1 0.23 11.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 RLN89436.1 - 0.039 13.1 0.5 3.2 6.8 0.0 2.2 2 0 0 2 2 2 0 TIP49 P-loop domain RuvB_N PF05496.12 RLN89436.1 - 0.049 13.4 0.0 0.63 9.8 0.0 2.7 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain DUF2791 PF10923.8 RLN89436.1 - 0.075 11.9 0.0 0.8 8.5 0.0 2.0 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) Atu4866 PF11512.8 RLN89436.1 - 0.081 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Agrobacterium tumefaciens protein Atu4866 Hpr_kinase_C PF07475.12 RLN89436.1 - 0.13 11.8 0.6 5.4 6.5 0.1 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Myb_DNA-binding PF00249.31 RLN89437.1 - 5.5e-10 39.3 0.1 2.4e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF515 PF04415.12 RLN89437.1 - 0.066 11.6 4.4 0.081 11.3 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Myb_DNA-binding PF00249.31 RLN89438.1 - 6e-11 42.4 0.0 6e-11 42.4 0.0 2.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain Paf1 PF03985.13 RLN89438.1 - 0.0076 15.3 1.1 0.0083 15.2 1.1 1.0 1 0 0 1 1 1 1 Paf1 DUF4200 PF13863.6 RLN89438.1 - 0.013 15.9 2.2 0.021 15.2 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DinB PF05163.12 RLN89438.1 - 0.069 13.1 0.4 0.099 12.6 0.4 1.2 1 0 0 1 1 1 0 DinB family GCP_C_terminal PF04130.13 RLN89438.1 - 0.14 11.6 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Gamma tubulin complex component C-terminal CENP-B_dimeris PF09026.10 RLN89438.1 - 1.5 9.3 6.0 1.8 9.0 5.3 1.6 1 1 0 1 1 1 0 Centromere protein B dimerisation domain Annexin PF00191.20 RLN89439.1 - 4.9e-42 141.9 3.9 9.2e-15 54.5 0.0 5.2 5 0 0 5 5 5 4 Annexin EAP30 PF04157.16 RLN89441.1 - 7.5e-41 139.9 0.3 9.5e-41 139.6 0.3 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 RLN89441.1 - 4.2e-16 58.9 0.0 7.7e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 RLN89441.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 GRAM domain WD40 PF00400.32 RLN89442.1 - 3.4e-45 151.1 17.0 4.7e-07 30.4 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN89442.1 - 1.9e-12 47.3 0.1 3.2e-05 24.1 0.0 5.4 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN89442.1 - 4.9e-07 28.8 4.7 0.11 11.2 0.2 5.0 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RLN89442.1 - 2e-06 27.0 4.4 0.36 9.8 0.0 4.3 1 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein CEP19 PF14933.6 RLN89442.1 - 2.3e-05 24.8 0.0 3.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 CEP19-like protein eIF2A PF08662.11 RLN89442.1 - 0.0069 16.3 0.1 0.73 9.7 0.1 2.8 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 RLN89442.1 - 0.12 11.9 0.1 0.32 10.6 0.1 1.9 1 1 0 1 1 1 0 PQQ-like domain Hira PF07569.11 RLN89442.1 - 2.8 7.6 9.5 0.23 11.2 0.6 3.5 4 1 0 5 5 5 0 TUP1-like enhancer of split Ras PF00071.22 RLN89443.1 - 1.4e-62 210.1 0.5 1.6e-62 209.9 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN89443.1 - 1.4e-32 112.4 0.2 2e-32 111.9 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN89443.1 - 4.4e-16 58.8 0.1 5.2e-16 58.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RLN89443.1 - 2e-07 30.8 0.2 2.8e-07 30.3 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 RLN89443.1 - 9.6e-05 21.8 0.1 0.00012 21.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 RLN89443.1 - 0.0069 15.8 0.1 0.0079 15.6 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ser_hydrolase PF06821.13 RLN89443.1 - 0.042 13.7 0.0 0.08 12.8 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase ATP_bind_1 PF03029.17 RLN89443.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Pkinase PF00069.25 RLN89444.1 - 1.9e-64 217.6 0.0 2.7e-64 217.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89444.1 - 5.7e-34 117.6 0.0 8.1e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN89444.1 - 1.4e-08 34.4 0.0 6e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 RLN89444.1 - 0.00034 20.0 0.4 0.00056 19.3 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN89444.1 - 0.00035 20.6 0.4 0.0015 18.5 0.2 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Gram_pos_anchor PF00746.21 RLN89445.1 - 0.14 12.1 0.6 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 LPXTG cell wall anchor motif REPA_OB_2 PF16900.5 RLN89446.1 - 0.011 15.6 0.0 3 7.8 0.0 2.8 2 0 0 2 2 2 0 Replication protein A OB domain Vps5 PF09325.10 RLN89446.1 - 0.027 14.0 0.1 0.046 13.3 0.1 1.3 1 0 0 1 1 1 0 Vps5 C terminal like Glyco_transf_90 PF05686.12 RLN89447.1 - 5.6e-21 74.9 7.0 6.5e-20 71.4 1.2 3.6 2 2 0 2 2 2 2 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 RLN89447.1 - 0.018 15.5 0.0 0.054 13.9 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 PAN_4 PF14295.6 RLN89448.1 - 1e-12 47.7 3.7 1e-12 47.7 3.7 1.9 2 0 0 2 2 2 1 PAN domain PAN_1 PF00024.26 RLN89448.1 - 6e-10 38.9 1.6 8e-10 38.6 1.6 1.2 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 RLN89448.1 - 0.16 12.1 7.5 0.3 11.2 7.5 1.7 1 1 0 1 1 1 0 PAN-like domain DUF2408 PF10303.9 RLN89449.1 - 0.017 15.7 0.6 0.08 13.5 0.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) HAUS2 PF15003.6 RLN89449.1 - 0.02 14.6 0.2 0.03 14.1 0.2 1.3 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 2 DUF4298 PF14131.6 RLN89449.1 - 0.06 13.3 0.3 0.13 12.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) Carn_acyltransf PF00755.20 RLN89452.1 - 2.4e-181 604.4 0.0 2.7e-181 604.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ICMT PF04140.14 RLN89453.1 - 5.4e-28 97.3 1.5 5.7e-28 97.2 0.3 1.6 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 RLN89453.1 - 7.6e-10 39.1 0.4 7.6e-10 39.1 0.4 2.2 3 0 0 3 3 3 1 Phospholipid methyltransferase PBP_N PF17093.5 RLN89453.1 - 0.13 12.6 0.4 0.23 11.7 0.4 1.3 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus CK2S PF15011.6 RLN89454.1 - 4.9e-05 23.3 0.8 0.00023 21.1 0.8 2.0 1 1 0 1 1 1 1 Casein Kinase 2 substrate PAN_4 PF14295.6 RLN89455.1 - 4.9e-37 125.6 43.3 3e-09 36.6 3.9 5.0 5 0 0 5 5 5 4 PAN domain PAN_1 PF00024.26 RLN89455.1 - 4e-27 94.0 17.7 7.9e-07 29.0 1.8 4.3 1 1 3 4 4 4 4 PAN domain PAN_2 PF08276.11 RLN89455.1 - 4.2e-05 23.6 37.4 0.03 14.4 3.6 4.3 4 0 0 4 4 4 4 PAN-like domain DUF4145 PF13643.6 RLN89456.1 - 0.074 13.2 0.7 1.1 9.5 0.0 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF4145) AAA_6 PF12774.7 RLN89458.1 - 1.2e-144 481.3 0.0 1.1e-143 478.1 0.0 2.4 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 RLN89458.1 - 1e-61 207.6 0.3 5.5e-55 185.7 0.0 3.4 3 0 0 3 3 3 3 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 RLN89458.1 - 5.3e-20 71.8 0.0 1.6e-19 70.3 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RLN89458.1 - 2.4e-11 43.8 0.1 2.2e-05 24.4 0.0 4.5 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA PF00004.29 RLN89458.1 - 4.5e-08 33.6 0.3 0.079 13.4 0.0 3.5 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN89458.1 - 1.1e-05 25.9 0.1 1.6 9.1 0.0 3.9 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 RLN89458.1 - 5.1e-05 23.6 0.8 2.8 8.2 0.1 3.9 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.6 RLN89458.1 - 0.00044 20.6 1.3 5 7.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 RLN89458.1 - 0.0005 20.6 0.0 1.4 9.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 RLN89458.1 - 0.003 17.9 0.1 1 9.8 0.0 3.1 3 0 0 3 3 3 1 RNA helicase T2SSE PF00437.20 RLN89458.1 - 0.0089 15.1 0.3 1.1 8.2 0.0 2.8 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_lid_1 PF17857.1 RLN89458.1 - 0.0098 16.1 0.2 0.029 14.6 0.1 2.0 2 0 0 2 2 1 1 AAA+ lid domain RuvB_N PF05496.12 RLN89458.1 - 0.011 15.5 0.0 20 4.9 0.1 3.4 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RLN89458.1 - 0.013 15.6 3.0 3.9 7.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 RLN89458.1 - 0.014 15.2 0.5 6.9 6.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 RLN89458.1 - 0.015 15.2 0.1 13 5.7 0.1 3.3 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_29 PF13555.6 RLN89458.1 - 0.034 13.9 0.1 0.14 11.9 0.1 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 RLN89458.1 - 0.035 14.1 1.4 4.2 7.4 0.2 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 RLN89458.1 - 0.043 14.3 0.0 0.091 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 RLN89458.1 - 0.044 13.2 0.4 0.24 10.8 0.1 2.4 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_30 PF13604.6 RLN89458.1 - 0.2 11.4 5.4 18 5.0 0.9 3.3 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 RLN89458.1 - 0.35 10.2 2.5 1.6 8.1 0.1 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Aminotran_1_2 PF00155.21 RLN89459.1 - 2.7e-79 267.0 1.0 7.5e-79 265.5 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 RLN89459.1 - 1.2e-05 24.0 0.0 2.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 RLN89459.1 - 7.1e-05 21.9 0.0 0.00014 20.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Preseq_ALAS PF09029.10 RLN89459.1 - 0.01 16.3 3.8 0.025 15.1 3.8 1.6 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence DEK_C PF08766.11 RLN89460.1 - 0.068 13.1 1.9 0.2 11.6 0.1 2.2 2 0 0 2 2 2 0 DEK C terminal domain DHBP_synthase PF00926.19 RLN89462.1 - 9.1e-81 270.0 0.0 1.4e-80 269.3 0.0 1.3 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 RLN89462.1 - 6.8e-06 25.8 0.1 0.12 12.0 0.0 3.4 2 1 1 3 3 3 2 GTP cyclohydrolase II MORN PF02493.20 RLN89462.1 - 0.072 13.0 0.5 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 MORN repeat Evr1_Alr PF04777.13 RLN89463.1 - 4.7e-18 65.5 0.3 1.2e-17 64.2 0.3 1.7 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.20 RLN89463.1 - 3.5e-17 62.3 0.2 7.1e-17 61.3 0.2 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 RLN89463.1 - 0.00011 22.6 0.6 0.00033 21.1 0.2 2.1 1 1 1 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 RLN89463.1 - 0.059 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 AhpC/TSA family DpnI PF06044.12 RLN89463.1 - 0.15 11.7 0.6 0.41 10.3 0.1 1.9 2 0 0 2 2 2 0 Dam-replacing family DUF1948 PF09185.10 RLN89463.1 - 0.16 11.8 0.1 0.44 10.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) DUF1849 PF08904.11 RLN89463.1 - 1.7 8.1 6.0 0.091 12.3 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1849) Zn_Tnp_IS1595 PF12760.7 RLN89463.1 - 2.4 8.2 8.7 3 7.9 0.6 2.9 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Sds3 PF08598.11 RLN89464.1 - 2e-06 28.0 5.9 3.2e-06 27.3 5.9 1.2 1 0 0 1 1 1 1 Sds3-like FKBP_N PF01346.18 RLN89465.1 - 0.067 14.1 5.4 0.65 11.0 2.5 2.1 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase SHR3_chaperone PF08229.11 RLN89465.1 - 0.47 9.4 1.5 0.87 8.5 1.5 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 FlxA PF14282.6 RLN89467.1 - 0.026 14.5 0.2 0.026 14.5 0.2 5.0 3 2 1 5 5 5 0 FlxA-like protein eIF-5_eIF-2B PF01873.17 RLN89467.1 - 0.79 9.6 9.6 1 9.3 3.0 2.8 2 1 0 2 2 2 0 Domain found in IF2B/IF5 TGase_elicitor PF16683.5 RLN89468.1 - 8.5e-181 600.5 0.7 1e-180 600.2 0.7 1.1 1 0 0 1 1 1 1 Transglutaminase elicitor Spa1_C PF18218.1 RLN89468.1 - 0.024 15.0 0.1 0.15 12.5 0.1 2.1 2 0 0 2 2 2 0 Lantibiotic immunity protein Spa1 C-terminal domain DUF3444 PF11926.8 RLN89468.1 - 0.09 12.4 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3444) SQAPI PF16845.5 RLN89469.1 - 0.0013 19.0 0.1 0.024 15.0 0.1 2.4 1 1 1 2 2 2 1 Aspartic acid proteinase inhibitor adh_short PF00106.25 RLN89470.1 - 9.6e-19 67.6 0.4 4.8e-13 49.0 0.1 2.5 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN89470.1 - 8.8e-12 45.1 0.1 6.6e-08 32.4 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase OrfB_Zn_ribbon PF07282.11 RLN89470.1 - 5.7e-06 26.2 3.7 0.026 14.4 0.5 2.5 2 0 0 2 2 2 2 Putative transposase DNA-binding domain NAD_binding_10 PF13460.6 RLN89470.1 - 0.00068 19.6 0.2 0.0037 17.2 0.0 2.2 2 1 1 3 3 3 1 NAD(P)H-binding Epimerase PF01370.21 RLN89470.1 - 0.0032 17.0 0.0 0.0053 16.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 RLN89470.1 - 0.0034 17.3 0.0 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 RLN89470.1 - 0.0034 17.0 0.0 0.0063 16.1 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family ADH_zinc_N PF00107.26 RLN89470.1 - 0.15 12.0 0.0 0.58 10.1 0.0 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Pkinase_Tyr PF07714.17 RLN89472.1 - 8.2e-40 136.7 0.0 1.1e-39 136.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN89472.1 - 1.4e-37 129.5 0.0 2.1e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.23 RLN89472.1 - 2.9e-28 97.0 7.7 5.4e-05 23.1 0.1 7.3 7 0 0 7 7 7 6 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN89472.1 - 1.4e-06 28.0 3.4 40 4.9 0.0 6.1 6 0 0 6 6 5 0 HEAT repeat HEAT_EZ PF13513.6 RLN89472.1 - 3.2e-05 24.3 8.8 0.0014 19.1 0.1 4.5 3 1 3 6 6 5 1 HEAT-like repeat Atx10homo_assoc PF09759.9 RLN89472.1 - 0.0035 17.3 0.0 2 8.5 0.0 3.3 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain DUF4439 PF14530.6 RLN89472.1 - 0.0099 16.6 7.7 1.2 9.8 0.2 4.3 3 1 1 5 5 5 2 Domain of unknown function (DUF4439) Kinase-like PF14531.6 RLN89472.1 - 0.029 13.7 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like HEAT_2 PF13646.6 RLN89472.1 - 0.12 12.8 21.3 0.91 10.0 2.2 4.9 3 1 4 7 7 7 0 HEAT repeats Arylsulfotran_N PF17425.2 RLN89472.1 - 0.16 12.0 0.0 2e+02 2.1 0.0 4.1 5 0 0 5 5 5 0 Arylsulfotransferase Ig-like domain HEAT_PBS PF03130.16 RLN89472.1 - 0.98 10.3 24.4 53 4.9 0.1 7.7 8 0 0 8 8 6 0 PBS lyase HEAT-like repeat Kinesin PF00225.23 RLN89473.1 - 2e-101 339.3 0.0 2.7e-101 338.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN89473.1 - 1.3e-24 86.9 0.0 2.5e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding FliJ PF02050.16 RLN89473.1 - 0.098 12.9 2.9 3.7 7.8 2.0 2.9 2 1 0 2 2 2 0 Flagellar FliJ protein ZapB PF06005.12 RLN89473.1 - 0.53 10.8 6.1 0.93 10.0 0.2 3.7 3 1 1 4 4 4 0 Cell division protein ZapB DivIVA PF05103.13 RLN89473.1 - 3.4 7.8 7.0 0.27 11.3 0.4 2.5 3 0 0 3 3 3 0 DivIVA protein DUF659 PF04937.15 RLN89474.1 - 1.4e-26 93.2 0.0 2.2e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 RLN89474.1 - 1.2e-08 34.6 0.0 3e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HSP70 PF00012.20 RLN89475.1 - 1.7e-154 515.3 1.2 1.9e-154 515.1 1.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN89475.1 - 2e-17 63.0 0.6 2.2e-15 56.3 0.2 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.18 RLN89475.1 - 0.0081 15.5 0.5 0.55 9.4 0.4 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase FliL PF03748.14 RLN89475.1 - 0.022 15.3 1.6 0.06 13.9 1.6 1.7 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL HOIP-UBA PF16678.5 RLN89475.1 - 0.063 13.3 0.1 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 HOIP UBA domain pair FtsA PF14450.6 RLN89475.1 - 0.076 13.4 0.1 9.1 6.8 0.0 2.7 2 1 0 2 2 2 0 Cell division protein FtsA Raco_middle PF17651.1 RLN89475.1 - 0.087 12.5 0.8 0.51 10.0 0.0 2.5 3 0 0 3 3 3 0 RACo middle region TOBE_3 PF12857.7 RLN89475.1 - 0.2 11.6 2.3 1.4 8.9 0.2 2.9 3 0 0 3 3 3 0 TOBE-like domain adh_short PF00106.25 RLN89477.1 - 1.1e-36 126.1 0.2 3.2e-36 124.6 0.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN89477.1 - 4.5e-22 78.7 0.1 1.9e-21 76.7 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN89477.1 - 1.5e-13 51.1 0.3 2.1e-13 50.6 0.3 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 RLN89477.1 - 0.0045 16.2 0.0 0.0066 15.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF4705 PF15788.5 RLN89477.1 - 0.055 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4705) NUDIX PF00293.28 RLN89478.1 - 9.9e-07 28.9 0.0 1.5e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain C2 PF00168.30 RLN89479.1 - 1.7e-18 66.8 0.0 3.7e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.17 RLN89479.1 - 0.13 12.9 0.0 3.3 8.4 0.0 2.9 2 0 0 2 2 2 0 Putative heavy-metal-binding Kelch_4 PF13418.6 RLN89480.1 - 1.2e-18 66.8 0.1 5.4e-05 23.1 0.0 4.9 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 RLN89480.1 - 4.3e-17 61.9 3.2 2.9e-05 24.2 0.1 5.8 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 RLN89480.1 - 2.5e-15 56.1 0.1 2e-06 27.9 0.1 4.4 3 1 1 4 4 4 3 Kelch motif Kelch_5 PF13854.6 RLN89480.1 - 2.2e-13 49.8 0.2 3.4e-06 26.9 0.1 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 RLN89480.1 - 1.8e-11 43.4 0.0 4e-05 23.1 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 RLN89480.1 - 0.00041 20.2 0.0 0.056 13.4 0.0 3.6 4 0 0 4 4 4 1 Kelch motif Tropomyosin_1 PF12718.7 RLN89480.1 - 0.25 11.5 11.0 0.92 9.7 1.1 2.4 2 0 0 2 2 2 0 Tropomyosin like DUF2335 PF10097.9 RLN89480.1 - 0.53 10.3 0.0 0.53 10.3 0.0 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2335) KELK PF15796.5 RLN89480.1 - 0.85 10.1 8.2 0.041 14.3 2.2 1.9 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase APG6_N PF17675.1 RLN89480.1 - 1.7 9.2 13.3 2.2 8.8 0.9 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Matrilin_ccoil PF10393.9 RLN89480.1 - 2.1 8.3 4.4 5.1 7.0 0.7 2.5 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Spc7 PF08317.11 RLN89480.1 - 2.5 6.9 9.0 7.8 5.3 3.1 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 RLN89480.1 - 2.8 8.2 11.9 5 7.5 1.9 3.0 2 1 0 2 2 2 0 ABC transporter C-terminal domain GAS PF13851.6 RLN89480.1 - 5 6.4 12.9 2.8 7.2 3.6 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 RLN89480.1 - 5.3 7.1 15.4 6.4 6.9 5.6 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Cortex-I_coil PF09304.10 RLN89480.1 - 6.6 7.0 10.5 1.5 9.1 1.6 2.7 3 0 0 3 3 3 0 Cortexillin I, coiled coil SGT1 PF07093.11 RLN89481.1 - 2.9e-92 310.0 0.9 9e-73 245.6 0.0 2.1 1 1 1 2 2 2 2 SGT1 protein Trypsin PF00089.26 RLN89482.1 - 2.6e-47 161.5 1.3 3.1e-47 161.2 1.3 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 RLN89482.1 - 4.1e-07 31.0 0.7 8.2e-07 30.0 0.7 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1729 PF08354.10 RLN89483.1 - 5.5e-133 443.2 0.0 1.2e-132 442.1 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) SAT PF16073.5 RLN89483.1 - 1e-30 107.2 0.5 2.4e-30 106.1 0.5 1.6 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_meander PF17951.1 RLN89483.1 - 1e-18 67.6 0.0 5.2e-18 65.3 0.0 2.1 2 0 0 2 2 2 1 Fatty acid synthase meander beta sheet domain Retrotran_gag_2 PF14223.6 RLN89484.1 - 9.3e-07 28.6 0.0 1.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type PAN_1 PF00024.26 RLN89485.1 - 1.5e-24 85.7 19.9 4.2e-07 29.8 1.6 4.7 4 0 0 4 4 4 4 PAN domain PAN_4 PF14295.6 RLN89485.1 - 2.3e-20 72.3 40.7 5e-10 39.1 3.1 5.4 5 0 0 5 5 5 4 PAN domain PAN_2 PF08276.11 RLN89485.1 - 0.012 15.7 0.3 0.012 15.7 0.3 4.9 5 0 0 5 5 5 0 PAN-like domain DUF4023 PF13215.6 RLN89486.1 - 0.16 12.0 0.3 0.31 11.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) zf-4CXXC_R1 PF10497.9 RLN89486.1 - 0.5 10.6 11.2 0.66 10.2 7.6 2.4 1 1 1 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 FYVE PF01363.21 RLN89488.1 - 2 8.6 9.4 4.3 7.6 9.4 1.6 1 0 0 1 1 1 0 FYVE zinc finger DUF2797 PF10977.8 RLN89489.1 - 4 7.3 6.5 1.2 9.0 3.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2797) DZR PF12773.7 RLN89489.1 - 7.7 6.6 8.0 1.1e+02 2.9 7.9 2.5 1 1 0 1 1 1 0 Double zinc ribbon Abhydrolase_3 PF07859.13 RLN89491.1 - 1.6e-30 106.6 0.0 2.6e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN89491.1 - 1.2e-11 44.2 0.0 1.6e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 RLN89491.1 - 0.021 14.3 0.0 0.098 12.1 0.0 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family LSM PF01423.22 RLN89492.1 - 1.7e-14 53.3 0.6 2.2e-14 52.9 0.6 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RLN89492.1 - 8.7e-05 22.6 0.0 0.00012 22.2 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain tRNA_anti_2 PF13742.6 RLN89492.1 - 0.065 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF4666 PF15697.5 RLN89492.1 - 0.12 13.0 0.3 0.2 12.4 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) Thioredoxin PF00085.20 RLN89493.1 - 0.0052 16.8 0.0 0.0066 16.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Bin3 PF06859.12 RLN89494.1 - 9.5e-38 129.2 0.0 1.4e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_12 PF08242.12 RLN89494.1 - 8.6e-12 45.7 0.0 5.2e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 RLN89494.1 - 6.4e-11 42.4 0.0 1.2e-10 41.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN89494.1 - 1.7e-10 40.9 0.0 2e-06 27.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 RLN89494.1 - 1.4e-09 38.6 0.0 1.2e-05 25.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 RLN89494.1 - 8.9e-07 29.5 0.0 0.0056 17.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain PrmA PF06325.13 RLN89494.1 - 0.0006 19.3 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 RLN89494.1 - 0.00066 19.2 0.1 0.0018 17.8 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.7 RLN89494.1 - 0.00068 19.6 0.0 0.0018 18.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.11 RLN89494.1 - 0.0089 15.7 0.0 0.15 11.6 0.0 2.1 2 0 0 2 2 2 1 Nodulation protein S (NodS) FtsJ PF01728.19 RLN89494.1 - 0.018 15.1 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 RLN89494.1 - 0.032 13.6 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 RLN89494.1 - 0.13 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Myb_DNA-binding PF00249.31 RLN89496.1 - 1e-09 38.4 0.1 1.8e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain PH PF00169.29 RLN89497.1 - 0.00051 20.5 0.0 0.00068 20.1 0.0 1.2 1 0 0 1 1 1 1 PH domain NUFIP1 PF10453.9 RLN89498.1 - 0.0049 16.7 0.0 0.0096 15.7 0.0 1.4 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) CBM_X2 PF03442.14 RLN89498.1 - 0.12 12.5 0.2 0.22 11.6 0.2 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain X2 Ribosomal_L34e PF01199.18 RLN89499.1 - 1.3 9.3 7.4 5.2 7.4 7.4 1.9 1 1 0 1 1 1 0 Ribosomal protein L34e CDC27 PF09507.10 RLN89499.1 - 2.9 7.2 24.4 0.31 10.4 19.9 1.7 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 DHC_N1 PF08385.12 RLN89500.1 - 1e-181 605.5 0.3 1e-181 605.5 0.3 3.0 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 RLN89500.1 - 1.7e-136 454.5 1.2 5.6e-74 249.0 0.0 3.1 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN89500.1 - 1e-102 344.3 0.0 1e-102 344.3 0.0 5.0 5 2 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RLN89500.1 - 1.1e-90 303.5 0.0 9.9e-89 297.1 0.0 3.2 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RLN89500.1 - 1.8e-80 269.2 0.1 2.1e-77 259.1 0.1 2.6 2 0 0 2 2 2 2 ATP-binding dynein motor region Dynein_C PF18199.1 RLN89500.1 - 3.5e-76 256.4 0.2 1.2e-73 248.1 0.0 3.8 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain MT PF12777.7 RLN89500.1 - 4.9e-75 252.7 14.1 8.5e-75 251.9 14.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 RLN89500.1 - 1.8e-65 219.8 0.0 1.5e-58 197.3 0.0 4.0 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 RLN89500.1 - 1.5e-38 131.6 0.1 4.3e-35 120.4 0.0 3.4 3 0 0 3 3 2 2 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 RLN89500.1 - 1.1e-36 126.2 0.0 2.9e-36 124.8 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RLN89500.1 - 1.9e-24 86.2 0.0 6.1e-09 36.0 0.0 5.3 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 RLN89500.1 - 4.5e-24 84.5 0.4 2e-23 82.5 0.1 2.4 2 0 0 2 2 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 RLN89500.1 - 1.2e-18 67.4 0.0 4.2e-18 65.7 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 RLN89500.1 - 1.2e-09 38.8 0.6 0.0046 17.3 0.0 5.8 6 0 0 6 6 4 2 AAA ATPase domain AAA PF00004.29 RLN89500.1 - 2.4e-07 31.2 1.0 0.53 10.7 0.0 5.8 6 0 0 6 6 5 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN89500.1 - 2.2e-06 28.0 0.0 1.1 9.5 0.0 4.9 3 1 1 4 4 3 2 AAA domain RNA_helicase PF00910.22 RLN89500.1 - 3.2e-05 24.3 0.0 25 5.3 0.0 4.8 4 0 0 4 4 4 0 RNA helicase RsgA_GTPase PF03193.16 RLN89500.1 - 4.7e-05 23.4 0.0 0.051 13.5 0.0 3.1 3 0 0 3 3 2 1 RsgA GTPase AAA_18 PF13238.6 RLN89500.1 - 0.00012 22.7 0.1 2.6 8.6 0.0 4.7 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.6 RLN89500.1 - 0.00015 21.5 0.1 4.9 7.0 0.0 4.1 3 0 0 3 3 3 1 P-loop containing region of AAA domain ABC_tran PF00005.27 RLN89500.1 - 0.00055 20.5 0.0 3.2 8.3 0.0 3.4 2 0 0 2 2 2 2 ABC transporter DUF815 PF05673.13 RLN89500.1 - 0.0006 19.1 0.0 0.2 10.8 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 RLN89500.1 - 0.0014 18.8 2.4 0.31 11.2 0.0 4.4 5 0 0 5 5 3 1 AAA domain TsaE PF02367.17 RLN89500.1 - 0.0018 18.3 0.3 20 5.2 0.0 4.5 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 RLN89500.1 - 0.0068 15.8 0.1 0.99 8.8 0.0 3.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 RLN89500.1 - 0.016 15.3 0.0 1 9.4 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 RLN89500.1 - 0.019 14.6 0.9 11 5.6 0.0 3.7 4 0 0 4 4 3 0 AAA domain Rad17 PF03215.15 RLN89500.1 - 0.036 14.0 0.0 1.2 9.0 0.0 3.1 3 0 0 3 3 3 0 Rad17 P-loop domain Roc PF08477.13 RLN89500.1 - 0.068 13.4 0.0 1.9 8.8 0.0 3.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 RLN89500.1 - 0.076 12.4 0.0 2.8 7.3 0.0 2.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_28 PF13521.6 RLN89500.1 - 0.084 13.1 0.0 78 3.5 0.0 3.7 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 RLN89500.1 - 0.1 11.9 0.1 2.5 7.4 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin DUF1664 PF07889.12 RLN89501.1 - 0.51 10.4 3.2 0.99 9.5 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 RLN89501.1 - 3 7.9 10.0 5 7.2 10.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF572 PF04502.13 RLN89501.1 - 7.2 6.1 14.0 9.6 5.7 14.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Trypsin_2 PF13365.6 RLN89503.1 - 2.5e-05 25.2 0.0 4.6e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain ESCRT-II PF05871.12 RLN89504.1 - 1.9e-32 112.4 0.0 2.9e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit DMRL_synthase PF00885.19 RLN89504.1 - 2.9e-24 85.5 0.2 4.7e-24 84.8 0.2 1.3 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Diedel PF13164.6 RLN89507.1 - 4.3 7.9 10.3 6.2 7.3 0.4 3.1 2 1 1 3 3 3 0 Diedel Sod_Cu PF00080.20 RLN89508.1 - 1.3e-34 119.4 3.6 1.6e-34 119.1 3.6 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Tub PF01167.18 RLN89509.1 - 1.5e-49 169.0 0.0 7.4e-49 166.7 0.0 1.9 1 1 0 1 1 1 1 Tub family PDZ_6 PF17820.1 RLN89509.1 - 7e-08 32.2 0.0 1.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RLN89509.1 - 0.0063 16.8 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain K-box PF01486.17 RLN89509.1 - 0.12 12.5 0.5 0.25 11.5 0.5 1.5 1 0 0 1 1 1 0 K-box region Cellsynth_D PF03500.13 RLN89511.1 - 0.57 10.0 2.5 4.5 7.2 0.1 3.0 2 1 1 3 3 3 0 Cellulose synthase subunit D ATP-grasp_4 PF13535.6 RLN89512.1 - 4e-22 78.5 0.0 1.2e-11 44.4 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain ATP-grasp_3 PF02655.14 RLN89512.1 - 3.1e-14 53.3 0.0 2e-06 27.9 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp domain LAL_C2 PF18603.1 RLN89512.1 - 1.7e-13 50.5 0.0 2.2e-07 30.9 0.0 3.2 3 0 0 3 3 3 2 L-amino acid ligase C-terminal domain 2 ATPgrasp_Ter PF15632.6 RLN89512.1 - 2.8e-09 36.8 0.1 0.011 15.5 0.0 4.6 3 2 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 RLN89512.1 - 1.3e-08 34.9 0.0 0.00012 21.9 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 RLN89512.1 - 0.00098 18.8 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 RLN89512.1 - 0.023 14.1 0.0 0.39 10.1 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain IQ PF00612.27 RLN89514.1 - 7e-05 22.3 30.4 0.011 15.5 0.6 5.7 5 1 1 6 6 6 3 IQ calmodulin-binding motif ABC2_membrane PF01061.24 RLN89515.1 - 5.3e-60 202.4 73.9 1.2e-32 113.0 27.6 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN89515.1 - 9.6e-34 116.8 0.1 1.6e-15 57.9 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 RLN89515.1 - 2.8e-08 34.3 0.2 0.0045 17.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 RLN89515.1 - 4.3e-08 32.8 0.6 0.007 16.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 RLN89515.1 - 3.1e-07 30.5 0.2 0.045 13.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system PDR_CDR PF06422.12 RLN89515.1 - 7e-07 29.1 4.5 3.4e-05 23.7 0.0 3.4 3 0 0 3 3 3 1 CDR ABC transporter RsgA_GTPase PF03193.16 RLN89515.1 - 9e-07 28.9 0.4 0.013 15.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 RLN89515.1 - 9.5e-06 25.2 0.6 0.02 14.3 0.1 2.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RLN89515.1 - 5.3e-05 23.5 0.0 0.45 10.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 RLN89515.1 - 0.00014 21.7 0.2 0.29 10.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 RLN89515.1 - 0.00016 22.2 0.0 0.9 10.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 RLN89515.1 - 0.00037 20.1 0.4 0.48 10.0 0.0 2.9 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 RLN89515.1 - 0.00044 19.6 0.7 0.067 12.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.29 RLN89515.1 - 0.00053 20.4 0.1 1.3 9.4 0.1 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 RLN89515.1 - 0.0014 19.2 0.1 0.32 11.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 RLN89515.1 - 0.0015 17.7 14.7 0.0015 17.7 14.7 3.1 2 2 0 2 2 2 1 ABC-2 family transporter protein MMR_HSR1 PF01926.23 RLN89515.1 - 0.004 17.2 2.1 0.67 10.1 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 RLN89515.1 - 0.0042 17.3 0.0 2.8 8.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 RLN89515.1 - 0.0081 16.1 0.8 0.71 9.8 0.0 2.4 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 NACHT PF05729.12 RLN89515.1 - 0.0086 16.0 1.7 3.4 7.6 0.3 2.7 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.17 RLN89515.1 - 0.016 15.3 3.2 0.87 9.6 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_19 PF13245.6 RLN89515.1 - 0.016 15.5 0.2 4.3 7.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain PDR_assoc PF08370.11 RLN89515.1 - 0.017 14.9 0.2 0.017 14.9 0.2 3.5 3 0 0 3 3 2 0 Plant PDR ABC transporter associated AAA_28 PF13521.6 RLN89515.1 - 0.017 15.4 0.2 1.1 9.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RLN89515.1 - 0.026 14.9 0.1 7.8 6.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 RLN89515.1 - 0.031 14.0 0.1 9.5 5.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 RLN89515.1 - 0.043 13.8 0.5 2.4 8.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Roc PF08477.13 RLN89515.1 - 0.083 13.1 0.1 14 5.9 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 RLN89515.1 - 0.083 12.5 1.1 2.9 7.4 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 RLN89515.1 - 0.11 11.6 0.6 0.31 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 RLN89515.1 - 0.11 12.5 0.5 3 7.8 0.1 2.6 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 RLN89515.1 - 0.14 11.9 0.6 5.1 6.8 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.9 RLN89515.1 - 0.23 10.6 0.1 1.6 7.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 RLN89515.1 - 0.4 10.2 1.3 3.8 7.0 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region COMM_domain PF07258.14 RLN89516.1 - 3.8e-10 39.7 0.0 5.9e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 COMM domain QH-AmDH_gamma PF08992.11 RLN89516.1 - 0.2 11.7 1.1 14 5.8 0.7 2.9 3 0 0 3 3 3 0 Quinohemoprotein amine dehydrogenase, gamma subunit WD40 PF00400.32 RLN89517.1 - 0.00015 22.4 8.8 0.55 11.2 0.0 5.3 5 1 0 5 5 5 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 RLN89517.1 - 0.1 11.5 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 RLN89517.1 - 0.11 12.2 0.1 0.45 10.3 0.0 2.1 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature WW PF00397.26 RLN89518.1 - 8.2e-15 54.6 13.5 7.4e-07 29.1 0.3 2.7 2 0 0 2 2 2 2 WW domain EF-hand_1 PF00036.32 RLN89518.1 - 3.4e-12 45.0 0.8 4.3e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN89518.1 - 1e-10 40.6 1.0 0.00015 21.4 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RLN89518.1 - 2.1e-10 40.9 0.6 7.2e-10 39.2 0.5 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RLN89518.1 - 1.4e-07 31.2 3.6 9.2e-07 28.6 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN89518.1 - 8e-07 28.3 3.8 0.0019 17.6 0.0 2.4 2 0 0 2 2 2 2 EF hand LRR_8 PF13855.6 RLN89518.1 - 0.025 14.3 0.0 0.095 12.5 0.0 2.0 1 1 0 1 1 1 0 Leucine rich repeat EF-hand_10 PF14788.6 RLN89518.1 - 0.026 14.4 0.4 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 EF hand DUF2782 PF11191.8 RLN89518.1 - 0.069 13.4 0.0 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2782) IQ PF00612.27 RLN89518.1 - 0.14 12.0 2.5 0.35 10.8 2.5 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Glyco_hyd_101C PF17451.2 RLN89518.1 - 5.4 7.3 6.1 2.8 8.3 0.5 2.7 3 0 0 3 3 2 0 Glycosyl hydrolase 101 beta sandwich domain SAPS PF04499.15 RLN89519.1 - 8.2e-07 28.2 0.0 1.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein DUF4611 PF15387.6 RLN89519.1 - 0.084 13.1 0.1 0.084 13.1 0.1 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4611) Kinesin PF00225.23 RLN89520.1 - 1.5e-68 231.2 0.6 1.5e-68 231.2 0.6 2.1 2 1 0 2 2 2 1 Kinesin motor domain Pkinase PF00069.25 RLN89521.1 - 4.1e-05 23.1 0.0 6.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 RLN89522.1 - 2.1e-44 151.9 0.0 3.3e-35 121.7 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89522.1 - 4.9e-32 111.2 0.0 2.1e-26 92.8 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN89522.1 - 3.4e-05 22.8 0.0 4.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN89522.1 - 0.002 17.5 0.0 0.0029 17.0 0.1 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RLN89522.1 - 0.13 11.2 0.0 11 4.8 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Hat1_N PF10394.9 RLN89524.1 - 5.3e-13 49.5 0.0 6e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Dynamin_N PF00350.23 RLN89525.1 - 7.7e-30 104.2 0.0 8.9e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 RLN89525.1 - 0.036 14.2 0.1 0.049 13.7 0.1 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 RLN89525.1 - 0.038 14.4 0.0 0.045 14.1 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 RLN89525.1 - 0.078 13.2 0.1 0.18 12.0 0.1 1.5 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 RLN89525.1 - 0.16 12.2 0.1 0.18 12.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain ACOX PF01756.19 RLN89526.1 - 2.4e-41 141.3 0.1 4.3e-41 140.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 RLN89526.1 - 2.2e-30 105.8 0.0 4.4e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 RLN89526.1 - 4.4e-13 49.2 0.0 2e-12 47.1 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 RLN89526.1 - 0.011 16.4 0.0 0.025 15.2 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 RLN89526.1 - 0.012 15.8 0.0 0.031 14.5 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain DUF2520 PF10728.9 RLN89527.1 - 0.049 13.4 0.2 0.098 12.4 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2520) ATP_bind_3 PF01171.20 RLN89528.1 - 1.3e-35 122.8 0.0 2.1e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF924 PF06041.11 RLN89528.1 - 4.6e-21 75.8 0.1 8e-21 75.0 0.1 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) QueC PF06508.13 RLN89528.1 - 7.7e-06 25.5 0.0 0.0011 18.6 0.0 2.4 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 RLN89528.1 - 1.1e-05 25.3 0.5 2.9e-05 23.9 0.1 1.8 1 1 1 2 2 2 1 Asparagine synthase tRNA_Me_trans PF03054.16 RLN89528.1 - 0.0005 19.0 0.0 0.0008 18.3 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 RLN89528.1 - 0.0021 17.7 0.0 0.018 14.6 0.0 2.1 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.17 RLN89528.1 - 0.023 13.8 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD synthase PAPS_reduct PF01507.19 RLN89528.1 - 0.084 12.9 0.0 0.28 11.2 0.0 1.9 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Prefoldin PF02996.17 RLN89529.1 - 3.1e-15 56.1 1.5 3.7e-14 52.7 0.0 2.5 2 0 0 2 2 2 1 Prefoldin subunit p25-alpha PF05517.12 RLN89529.1 - 0.0015 18.7 0.0 1.7 8.8 0.0 3.0 2 2 0 2 2 2 2 p25-alpha R2K_3 PF14243.6 RLN89529.1 - 0.0059 16.6 1.8 0.017 15.2 1.8 1.7 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 3 R2K_2 PF18299.1 RLN89529.1 - 0.046 13.6 0.3 3.2 7.6 0.3 2.4 2 0 0 2 2 2 0 ATP-grasp domain, R2K clade family 2 CH PF00307.31 RLN89529.1 - 0.055 13.7 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Calponin homology (CH) domain DUF724 PF05266.14 RLN89529.1 - 0.059 13.2 2.4 0.14 11.9 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FAM76 PF16046.5 RLN89529.1 - 0.31 10.4 0.8 0.64 9.3 0.8 1.5 1 0 0 1 1 1 0 FAM76 protein FTA4 PF13093.6 RLN89529.1 - 0.98 9.3 6.6 0.87 9.4 0.2 2.8 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 CSD PF00313.22 RLN89530.1 - 3.5e-26 90.9 18.2 7.6e-08 32.1 0.8 9.4 9 0 0 9 9 9 4 'Cold-shock' DNA-binding domain R3H PF01424.22 RLN89530.1 - 1.3e-06 28.3 0.0 3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 R3H domain S1-like PF14444.6 RLN89530.1 - 0.0011 18.9 4.1 15 5.6 0.0 6.0 5 1 0 5 5 5 1 S1-like S1_2 PF13509.6 RLN89530.1 - 1.2 9.3 4.3 1.2 9.2 0.3 2.8 3 0 0 3 3 3 0 S1 domain Pur_ac_phosph_N PF16656.5 RLN89531.1 - 5.3e-16 59.0 0.3 1e-15 58.0 0.3 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain 2TM PF13239.6 RLN89532.1 - 0.04 14.2 0.2 0.068 13.5 0.2 1.2 1 0 0 1 1 1 0 2TM domain PKD_channel PF08016.12 RLN89532.1 - 0.063 11.9 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 Polycystin cation channel Carn_acyltransf PF00755.20 RLN89533.1 - 1.3e-137 460.0 0.0 3.5e-136 455.2 0.0 2.0 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Nop14 PF04147.12 RLN89534.1 - 0.0073 14.6 8.7 0.0094 14.2 8.7 1.1 1 0 0 1 1 1 1 Nop14-like family DUF4637 PF15470.6 RLN89534.1 - 0.04 13.6 3.3 0.06 13.1 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RXT2_N PF08595.11 RLN89534.1 - 0.043 13.9 4.3 0.065 13.3 4.3 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal PAS_6 PF08348.11 RLN89534.1 - 0.045 13.6 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 YheO-like PAS domain CDC45 PF02724.14 RLN89534.1 - 0.066 11.5 5.2 0.091 11.0 5.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 RLN89534.1 - 0.11 12.3 4.6 0.16 11.8 4.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4611 PF15387.6 RLN89534.1 - 0.15 12.3 9.0 0.34 11.2 9.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Sigma70_ner PF04546.13 RLN89534.1 - 0.15 11.9 6.9 0.23 11.3 6.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region AIM3 PF17096.5 RLN89534.1 - 0.16 12.9 1.0 0.29 12.1 1.0 1.4 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 MPP6 PF10175.9 RLN89534.1 - 0.19 12.2 4.3 0.35 11.4 4.3 1.4 1 0 0 1 1 1 0 M-phase phosphoprotein 6 BUD22 PF09073.10 RLN89534.1 - 0.22 10.8 6.7 0.28 10.5 6.7 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 RLN89534.1 - 0.23 9.5 14.7 0.28 9.2 14.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 RLN89534.1 - 0.33 10.6 5.6 0.51 10.0 5.6 1.3 1 0 0 1 1 1 0 FAM176 family SDA1 PF05285.12 RLN89534.1 - 0.35 10.3 10.3 0.57 9.5 10.3 1.3 1 0 0 1 1 1 0 SDA1 Paf1 PF03985.13 RLN89534.1 - 0.41 9.6 7.9 0.56 9.2 7.9 1.1 1 0 0 1 1 1 0 Paf1 TRAP_alpha PF03896.16 RLN89534.1 - 0.62 9.2 3.9 0.83 8.8 3.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4820 PF16091.5 RLN89534.1 - 0.76 9.1 4.4 1.1 8.6 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF2457 PF10446.9 RLN89534.1 - 1.1 8.4 18.5 1.5 7.9 18.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Radial_spoke PF04712.12 RLN89534.1 - 2.2 7.1 7.6 2.8 6.8 7.6 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein NOA36 PF06524.12 RLN89534.1 - 2.2 7.5 16.1 3.1 7.0 16.1 1.1 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.12 RLN89534.1 - 3.1 7.1 11.0 4.2 6.7 11.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PBP1_TM PF14812.6 RLN89534.1 - 3.8 7.9 12.0 9 6.7 12.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.11 RLN89534.1 - 4.1 5.4 7.5 5.7 4.9 7.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cytomega_UL84 PF06284.11 RLN89534.1 - 5.1 5.4 4.9 6.3 5.1 4.9 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Cwf_Cwc_15 PF04889.12 RLN89534.1 - 9.7 5.8 13.7 15 5.2 13.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pkinase PF00069.25 RLN89535.1 - 6.1e-51 173.3 0.0 1.6e-50 171.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89535.1 - 5.5e-45 153.7 0.0 7.7e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Adeno_E3_CR2 PF02439.15 RLN89535.1 - 0.0098 15.6 0.6 0.021 14.6 0.6 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Kdo PF06293.14 RLN89535.1 - 0.077 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN89535.1 - 0.19 11.6 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family VPDSG-CTERM PF18205.1 RLN89535.1 - 1 9.3 2.7 2.9 7.8 2.7 1.8 1 0 0 1 1 1 0 VPDSG-CTERM motif DUF4267 PF14087.6 RLN89537.1 - 0.027 14.5 0.0 3.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) LRR_6 PF13516.6 RLN89538.1 - 4.5e-20 69.9 13.3 0.0037 17.2 0.0 8.6 8 0 0 8 8 8 6 Leucine Rich repeat EF-hand_1 PF00036.32 RLN89538.1 - 2.4e-11 42.3 0.6 0.00019 20.8 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN89538.1 - 3.8e-09 35.8 0.7 0.00041 20.0 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RLN89538.1 - 1.5e-08 34.9 0.8 3.8e-08 33.7 0.8 1.7 1 0 0 1 1 1 1 EF-hand domain pair LRR_1 PF00560.33 RLN89538.1 - 0.00022 21.3 2.5 45 5.1 0.0 6.5 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_4 PF12799.7 RLN89538.1 - 0.0011 19.4 7.6 4.7 7.8 1.0 4.5 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) DUF4476 PF14771.6 RLN89538.1 - 0.0014 18.9 0.0 2.4 8.5 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4476) EF-hand_8 PF13833.6 RLN89538.1 - 0.0075 16.1 1.6 0.036 13.9 0.4 2.6 2 1 1 3 3 3 1 EF-hand domain pair LRR_8 PF13855.6 RLN89538.1 - 0.067 13.0 13.3 2 8.2 2.0 5.6 3 2 1 4 4 4 0 Leucine rich repeat EF-hand_5 PF13202.6 RLN89538.1 - 0.1 12.2 0.3 17 5.1 0.0 2.7 2 0 0 2 2 2 0 EF hand RWP-RK PF02042.15 RLN89539.1 - 4.6e-18 64.9 0.1 9.3e-18 63.9 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain WD40 PF00400.32 RLN89541.1 - 1e-19 70.5 8.6 4.4e-06 27.3 0.1 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN89541.1 - 7e-13 48.7 0.1 0.013 15.8 0.0 5.0 4 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain GAS PF13851.6 RLN89541.1 - 0.0031 16.9 6.1 0.0031 16.9 6.1 3.7 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 RLN89541.1 - 0.0075 16.4 7.4 0.0075 16.4 7.4 3.8 3 1 0 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus Nup160 PF11715.8 RLN89541.1 - 0.0085 14.8 0.1 0.53 8.9 0.0 2.9 4 0 0 4 4 4 1 Nucleoporin Nup120/160 HAGH_C PF16123.5 RLN89542.1 - 1.6e-25 89.4 0.0 2.8e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 RLN89542.1 - 1.6e-12 47.9 2.2 3.3e-12 46.8 2.2 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 RLN89542.1 - 0.00049 20.0 0.1 0.00093 19.1 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 RLN89542.1 - 0.00052 19.6 0.1 0.0011 18.5 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Barttin PF15462.6 RLN89544.1 - 0.027 14.2 2.0 0.032 14.0 2.0 1.1 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) NAD_synthase PF02540.17 RLN89545.1 - 2.6e-07 30.0 0.0 0.00017 20.8 0.0 2.2 2 0 0 2 2 2 2 NAD synthase tRNA_Me_trans PF03054.16 RLN89545.1 - 2.1e-06 26.8 0.0 0.0019 17.1 0.1 2.2 2 0 0 2 2 2 2 tRNA methyl transferase Asn_synthase PF00733.21 RLN89545.1 - 0.0002 21.1 0.1 0.0005 19.8 0.0 1.6 2 0 0 2 2 2 1 Asparagine synthase QueC PF06508.13 RLN89545.1 - 0.0022 17.6 0.6 0.85 9.1 0.1 2.7 2 1 1 3 3 3 2 Queuosine biosynthesis protein QueC PAP_central PF04928.17 RLN89545.1 - 0.08 11.9 1.1 1 8.3 0.1 2.1 2 0 0 2 2 2 0 Poly(A) polymerase central domain GST_N_3 PF13417.6 RLN89546.1 - 2.8e-10 40.4 0.0 4.5e-09 36.6 0.0 2.4 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RLN89546.1 - 1.4e-09 38.1 0.0 2.7e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN89546.1 - 5.7e-07 29.7 0.0 4.5e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RLN89546.1 - 5.3e-06 26.6 0.0 8.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RLN89546.1 - 0.00017 21.7 0.1 0.00047 20.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 RLN89546.1 - 0.075 13.3 0.0 0.35 11.2 0.0 1.8 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein Esterase_phd PF10503.9 RLN89546.1 - 0.091 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase LSDAT_euk PF18139.1 RLN89546.1 - 0.15 11.5 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 SLOG in TRPM MCM6_C PF18263.1 RLN89548.1 - 1.1e-23 83.5 13.3 1.2e-22 80.2 13.3 2.1 1 1 0 1 1 1 1 MCM6 C-terminal winged-helix domain MLIP PF15274.6 RLN89548.1 - 0.0038 17.2 0.2 0.0054 16.7 0.2 1.3 1 0 0 1 1 1 1 Muscular LMNA-interacting protein PGA2 PF07543.12 RLN89548.1 - 3.3 7.7 17.9 2.3 8.2 5.2 2.2 1 1 1 2 2 2 0 Protein trafficking PGA2 Pkinase_Tyr PF07714.17 RLN89549.1 - 0.0051 16.1 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 RLN89551.1 - 2.9e-09 37.4 0.0 6.8e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 PH domain ACBP PF00887.19 RLN89551.1 - 1.2e-05 25.4 0.0 3.3e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Acyl CoA binding protein FYVE PF01363.21 RLN89551.1 - 0.00022 21.3 6.2 0.00041 20.4 6.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger IQ_SEC7_PH PF16453.5 RLN89551.1 - 0.097 12.6 0.0 0.23 11.4 0.0 1.6 2 0 0 2 2 2 0 PH domain Arm PF00514.23 RLN89552.1 - 2.5e-22 78.2 9.8 1.4e-05 24.9 0.0 6.7 7 0 0 7 7 7 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN89552.1 - 6.6e-11 42.5 15.1 0.0053 17.2 0.5 5.9 5 2 1 6 6 6 4 HEAT-like repeat HEAT PF02985.22 RLN89552.1 - 1.4e-08 34.2 7.6 2.7 8.5 0.0 6.8 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.6 RLN89552.1 - 0.0069 16.7 18.6 0.078 13.4 1.2 4.1 3 1 1 4 4 4 3 HEAT repeats VWA_2 PF13519.6 RLN89552.1 - 0.023 15.3 0.2 15 6.3 0.1 3.0 1 1 2 3 3 3 0 von Willebrand factor type A domain Stealth_CR4 PF17103.5 RLN89552.1 - 0.097 12.6 0.9 0.66 9.9 0.1 2.6 3 0 0 3 3 3 0 Stealth protein CR4, conserved region 4 Succ_CoA_lig PF13607.6 RLN89552.1 - 0.51 10.1 2.7 5.4 6.8 0.0 3.4 3 1 1 4 4 4 0 Succinyl-CoA ligase like flavodoxin domain Actin PF00022.19 RLN89553.1 - 5.5e-48 163.6 0.0 1e-46 159.4 0.0 2.2 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 RLN89553.1 - 0.037 12.9 0.0 0.1 11.4 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein Glyco_hydro_43 PF04616.14 RLN89554.1 - 2.4e-37 128.8 1.5 3.4e-37 128.3 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_43 PF04616.14 RLN89555.1 - 5.9e-33 114.4 1.5 9.7e-33 113.7 1.5 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Mg_trans_NIPA PF05653.14 RLN89556.1 - 4.1e-22 78.6 15.7 6.6e-17 61.5 3.7 2.1 1 1 1 2 2 2 2 Magnesium transporter NIPA DUF2807 PF10988.8 RLN89556.1 - 4.8e-07 29.8 2.1 1.2e-06 28.4 2.1 1.7 1 1 0 1 1 1 1 Putative auto-transporter adhesin, head GIN domain PUFD PF16553.5 RLN89556.1 - 0.18 12.0 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 BCORL-PCGF1-binding domain Ank_2 PF12796.7 RLN89557.1 - 0.022 15.4 0.0 0.044 14.4 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN89557.1 - 0.1 13.2 0.1 0.26 11.9 0.1 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Chromo PF00385.24 RLN89558.1 - 5.8e-13 48.5 4.1 9.2e-10 38.3 0.5 3.2 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Glyco_hydro_43 PF04616.14 RLN89559.1 - 8.6e-33 113.9 1.6 1.4e-32 113.2 1.6 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Pkinase_Tyr PF07714.17 RLN89560.1 - 1.2e-51 175.5 0.0 1.6e-44 152.2 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN89560.1 - 3.1e-45 154.6 0.0 6.3e-37 127.4 0.0 3.0 3 1 0 3 3 3 2 Protein kinase domain Pkinase_fungal PF17667.1 RLN89560.1 - 0.0015 17.4 0.0 0.0046 15.8 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 RLN89560.1 - 0.071 13.0 0.2 0.071 13.0 0.2 3.5 3 2 1 4 4 4 0 Phosphotransferase enzyme family RIO1 PF01163.22 RLN89560.1 - 0.16 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family BT1 PF03092.16 RLN89562.1 - 3.8e-11 41.9 5.6 8.1e-11 40.8 0.3 2.6 1 1 1 2 2 2 2 BT1 family PUCC PF03209.15 RLN89562.1 - 0.013 14.5 11.2 0.043 12.8 7.6 2.6 2 1 0 2 2 2 0 PUCC protein Mg_trans_NIPA PF05653.14 RLN89563.1 - 1.2e-32 113.2 17.5 1.6e-32 112.8 17.5 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 RLN89563.1 - 0.00059 20.0 7.5 0.00059 20.0 7.5 3.3 2 1 0 3 3 3 1 EamA-like transporter family Fz PF01392.22 RLN89563.1 - 0.0063 17.1 4.3 0.01 16.4 4.3 1.3 1 0 0 1 1 1 1 Fz domain EmrE PF13536.6 RLN89563.1 - 0.0082 15.8 1.8 0.0082 15.8 1.8 2.2 2 0 0 2 2 2 1 Putative multidrug resistance efflux transporter TMEM234 PF10639.9 RLN89563.1 - 0.13 12.3 8.8 0.11 12.6 1.4 2.4 2 0 0 2 2 2 0 Putative transmembrane family 234 PIP5K PF01504.18 RLN89564.1 - 6.5e-43 146.9 0.0 1.3e-42 145.9 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase OmpA_like PF16961.5 RLN89564.1 - 0.045 13.4 0.1 0.082 12.6 0.0 1.5 2 0 0 2 2 2 0 Putative OmpA-OmpF-like porin family EF-hand_7 PF13499.6 RLN89565.1 - 2.3e-15 56.8 0.0 0.0014 19.0 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_8 PF13833.6 RLN89565.1 - 5.4e-06 26.2 0.1 0.056 13.3 0.0 4.9 5 1 1 6 6 6 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN89565.1 - 2.3e-05 23.6 0.0 6 6.7 0.0 6.1 6 0 0 6 6 6 1 EF hand RIIa PF02197.17 RLN89565.1 - 0.081 12.6 0.9 1.3 8.8 0.9 2.5 1 1 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Glycos_trans_3N PF02885.17 RLN89565.1 - 0.15 11.9 0.9 3.4 7.6 0.1 3.1 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain Peptidase_M13_N PF05649.13 RLN89566.1 - 6.7e-71 240.0 0.0 1.5e-70 238.8 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.21 RLN89566.1 - 3.6e-59 199.8 0.0 9.4e-59 198.5 0.0 1.8 1 0 0 1 1 1 1 Peptidase family M13 SAM_1 PF00536.30 RLN89566.1 - 7.5e-15 55.1 0.1 1.6e-14 54.1 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RLN89566.1 - 1.2e-12 47.7 0.1 2.9e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EF-hand_1 PF00036.32 RLN89566.1 - 6.3e-05 22.2 0.1 0.0013 18.2 0.1 3.3 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 RLN89566.1 - 0.00012 22.4 0.2 0.0086 16.5 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN89566.1 - 0.00022 20.9 0.6 0.0012 18.6 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain dCMP_cyt_deam_1 PF00383.23 RLN89566.1 - 0.00041 20.2 0.2 0.0011 18.8 0.2 1.7 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SAM_PNT PF02198.16 RLN89566.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain EF-hand_5 PF13202.6 RLN89566.1 - 0.15 11.6 4.8 0.15 11.6 0.9 2.8 2 0 0 2 2 2 0 EF hand Pkinase PF00069.25 RLN89567.1 - 1.5e-70 237.6 0.0 2.4e-70 236.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89567.1 - 5.1e-34 117.7 0.1 8.9e-34 116.9 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 RLN89567.1 - 0.0045 17.5 0.0 0.013 16.0 0.0 1.8 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 RLN89567.1 - 0.0077 16.5 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Kdo PF06293.14 RLN89567.1 - 0.012 15.0 0.4 0.024 14.0 0.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RLN89567.1 - 0.016 14.2 0.1 0.023 13.6 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 RLN89567.1 - 0.067 13.1 0.7 0.34 10.8 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 RLN89567.1 - 0.11 11.5 0.1 0.17 10.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HTH_Tnp_1 PF01527.20 RLN89568.1 - 0.0014 18.9 0.2 0.002 18.4 0.2 1.3 1 0 0 1 1 1 1 Transposase PX PF00787.24 RLN89569.1 - 1.7e-05 24.7 0.3 3.5e-05 23.8 0.3 1.6 1 0 0 1 1 1 1 PX domain IRK_C PF17655.1 RLN89570.1 - 8.4e-23 80.9 0.0 3e-11 43.3 0.0 2.2 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 RLN89570.1 - 2e-14 53.6 3.6 4.6e-12 46.0 3.6 2.3 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 RLN89570.1 - 0.00065 19.6 8.4 0.0013 18.6 8.4 1.5 1 0 0 1 1 1 1 Ion channel Saf_2TM PF18303.1 RLN89570.1 - 0.39 10.3 2.6 0.33 10.5 1.0 1.6 1 1 0 1 1 1 0 SAVED-fused 2TM effector domain TIM PF00121.18 RLN89571.1 - 4.1e-06 26.4 0.0 5e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase AMPK1_CBM PF16561.5 RLN89571.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase Yippee-Mis18 PF03226.14 RLN89572.1 - 1.2e-23 83.4 0.0 1.9e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Seryl_tRNA_N PF02403.22 RLN89572.1 - 0.02 15.1 0.2 0.02 15.1 0.2 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BROMI PF14961.6 RLN89572.1 - 0.084 10.3 3.2 0.81 7.0 0.1 2.0 2 0 0 2 2 2 0 Broad-minded protein Apo-CII PF05355.11 RLN89572.1 - 0.12 12.6 0.1 0.32 11.2 0.0 1.7 2 0 0 2 2 2 0 Apolipoprotein C-II RXT2_N PF08595.11 RLN89572.1 - 0.49 10.4 10.0 2.3 8.2 0.3 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal RNA_pol_3_Rpc31 PF11705.8 RLN89572.1 - 0.85 9.8 14.5 2.4 8.3 6.6 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 PBP1_TM PF14812.6 RLN89572.1 - 3.8 8.0 13.2 10 6.6 0.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 RLN89572.1 - 4.9 7.6 17.2 4 7.9 0.4 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TFB6 PF17110.5 RLN89572.1 - 9.8 5.9 10.0 19 5.0 4.5 2.2 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Ribosomal_L17 PF01196.19 RLN89573.1 - 5.8e-33 113.7 0.6 9.2e-33 113.0 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 Pkinase PF00069.25 RLN89574.1 - 7.3e-33 114.0 0.0 5.1e-22 78.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89574.1 - 9.3e-15 54.6 0.0 5e-14 52.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN89574.1 - 1.6e-05 24.4 0.0 0.00014 21.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like PRKCSH-like PF12999.7 RLN89575.1 - 6e-29 101.1 6.3 6e-29 101.1 6.3 3.1 3 1 0 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 RLN89575.1 - 3.7e-23 81.9 0.0 1.2e-22 80.3 0.0 1.8 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 RLN89575.1 - 0.0029 18.6 0.6 0.033 15.2 0.0 2.9 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein Phage_TAC_11 PF11836.8 RLN89575.1 - 0.031 14.4 0.4 0.031 14.4 0.4 2.3 2 0 0 2 2 2 0 Phage tail tube protein, GTA-gp10 RhoGEF67_u2 PF16614.5 RLN89575.1 - 2.7 8.1 8.3 19 5.4 3.2 2.5 2 0 0 2 2 2 0 Unstructured region two on RhoGEF 6 and 7 TAF4 PF05236.14 RLN89576.1 - 0.0017 18.2 6.2 0.002 17.9 6.2 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Coiled-coil_56 PF09813.9 RLN89576.1 - 0.016 15.2 6.0 0.032 14.3 6.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 GTA_holin_3TM PF11351.8 RLN89576.1 - 0.42 11.2 3.8 0.64 10.6 3.8 1.3 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release DUF4407 PF14362.6 RLN89576.1 - 0.83 8.9 5.2 1.1 8.6 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 RLN89576.1 - 0.92 9.4 12.8 1.1 9.2 12.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TERB2 PF15101.6 RLN89576.1 - 1.3 9.1 7.6 5.6 7.0 6.6 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 MAJIN PF15077.6 RLN89576.1 - 2.8 7.7 7.7 3.6 7.3 7.7 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein TPR_12 PF13424.6 RLN89578.1 - 0.00023 21.4 8.5 0.00023 21.4 8.5 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat ATP-synt PF00231.19 RLN89579.1 - 2.7e-34 119.2 0.1 3.2e-34 118.9 0.1 1.1 1 0 0 1 1 1 1 ATP synthase Pkinase PF00069.25 RLN89580.1 - 3.2e-77 259.5 0.0 3.9e-77 259.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89580.1 - 1.8e-31 109.4 0.0 2.5e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RLN89580.1 - 5e-06 25.7 0.0 7.5e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RLN89580.1 - 7.8e-05 22.1 0.0 0.00035 20.0 0.0 1.8 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 RLN89580.1 - 0.014 15.3 0.1 0.061 13.2 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 RLN89580.1 - 0.019 14.1 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 RLN89580.1 - 0.093 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_4 PF13637.6 RLN89584.1 - 4.9e-11 42.9 0.6 0.0038 17.8 0.1 4.5 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN89584.1 - 2.1e-09 37.9 1.2 0.048 14.2 0.1 3.5 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN89584.1 - 0.001 19.4 1.3 7.9 6.9 0.0 4.7 3 2 2 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN89584.1 - 0.023 15.2 0.3 90 4.2 0.0 4.2 4 0 0 4 4 4 0 Ankyrin repeat Ank PF00023.30 RLN89584.1 - 0.033 14.6 1.0 71 4.1 0.0 4.5 3 1 1 4 4 4 0 Ankyrin repeat Pkinase PF00069.25 RLN89586.1 - 2.7e-59 200.7 0.0 3.3e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89586.1 - 1.4e-30 106.4 0.0 2.2e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN89586.1 - 1.6e-05 24.4 0.1 0.00011 21.7 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN89586.1 - 3.5e-05 23.9 2.4 0.0014 18.6 0.2 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN89586.1 - 0.0017 17.2 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN89586.1 - 0.02 14.3 0.1 0.11 11.7 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Peptidase_C48 PF02902.19 RLN89587.1 - 2.8e-21 76.4 3.8 6.8e-12 45.7 0.3 2.4 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain COX17 PF05051.13 RLN89588.1 - 4.3e-18 65.4 5.2 4.3e-18 65.4 5.2 2.0 2 0 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) Fascin PF06268.13 RLN89588.1 - 0.08 13.2 0.2 0.62 10.3 0.0 2.3 2 0 0 2 2 2 0 Fascin domain Hep_core_N PF08290.11 RLN89588.1 - 0.49 10.4 3.9 1.8 8.6 3.9 2.0 1 0 0 1 1 1 0 Hepatitis core protein, putative zinc finger DUF179 PF02622.15 RLN89589.1 - 2.2e-22 79.7 0.0 3.3e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 EFG_C PF00679.24 RLN89591.1 - 3.9e-10 39.6 0.0 8.1e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 RLN89591.1 - 0.00071 19.4 0.0 0.0026 17.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV Pcc1 PF09341.10 RLN89591.1 - 0.047 13.8 0.0 0.19 11.9 0.0 2.0 1 0 0 1 1 1 0 Transcription factor Pcc1 GTP_EFTU_D2 PF03144.25 RLN89591.1 - 0.16 12.4 0.4 0.43 11.0 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu domain 2 DOT1 PF08123.13 RLN89594.1 - 5.7e-06 26.0 0.0 2.1e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Histone methylation protein DOT1 CMAS PF02353.20 RLN89594.1 - 0.0002 20.8 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 RLN89594.1 - 0.00079 20.1 1.2 0.027 15.2 1.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN89594.1 - 0.0011 18.8 0.0 0.0016 18.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 RLN89594.1 - 0.0011 18.8 0.3 0.0023 17.7 0.3 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.18 RLN89594.1 - 0.0036 17.0 0.1 0.0068 16.1 0.1 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 RLN89594.1 - 0.004 16.9 0.0 0.006 16.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN89594.1 - 0.0067 17.1 1.0 0.096 13.3 1.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 RLN89594.1 - 0.034 13.2 0.1 1.3 8.0 0.0 2.3 2 1 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.17 RLN89594.1 - 0.047 13.2 0.1 0.079 12.4 0.1 1.7 1 1 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.12 RLN89594.1 - 0.049 14.4 0.0 0.065 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 RLN89594.1 - 0.056 12.7 0.1 0.79 9.0 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase domain TehB PF03848.14 RLN89594.1 - 0.061 12.7 0.0 0.42 10.0 0.0 1.9 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_11 PF08241.12 RLN89595.1 - 1.4e-10 41.7 0.0 6e-10 39.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN89595.1 - 2.2e-08 34.7 0.4 3.7e-07 30.8 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN89595.1 - 1.6e-07 31.2 0.0 3.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN89595.1 - 6.8e-05 22.8 0.0 0.0003 20.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN89595.1 - 0.0027 18.4 0.0 0.027 15.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain MutS_V PF00488.21 RLN89596.1 - 9e-25 87.8 0.0 1.9e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 RLN89596.1 - 0.0017 18.6 0.0 0.003 17.8 0.0 1.4 1 1 0 1 1 1 1 MutS domain III Ig_mannosidase PF17753.1 RLN89598.1 - 5.6e-10 38.8 0.2 1.4e-09 37.5 0.2 1.7 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 RLN89598.1 - 2.8e-06 28.0 0.0 5.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 RLN89598.1 - 2.8e-05 24.1 0.1 0.00016 21.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain 4PPT_N PF17837.1 RLN89598.1 - 0.11 12.6 0.4 22 5.3 0.0 2.5 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain PX PF00787.24 RLN89599.1 - 3.7e-10 39.8 0.0 6.6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 PX domain BCDHK_Adom3 PF10436.9 RLN89600.1 - 1.4e-26 93.2 2.3 1e-09 38.5 0.0 4.3 2 2 2 4 4 4 4 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 RLN89600.1 - 6.7e-21 74.9 0.0 4.9e-10 39.9 0.0 2.9 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 RLN89600.1 - 0.0057 16.6 0.0 9.3 6.2 0.0 3.2 4 0 0 4 4 4 2 Histidine kinase-like ATPase domain Asp_Glu_race_2 PF14669.6 RLN89600.1 - 0.018 14.7 0.0 3.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Putative aspartate racemase HATPase_c_3 PF13589.6 RLN89600.1 - 0.023 14.5 0.0 0.24 11.2 0.0 2.4 2 1 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF5441 PF17513.2 RLN89600.1 - 0.032 14.0 0.3 8.5 6.1 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5441) DAGAT PF03982.13 RLN89600.1 - 0.043 12.7 0.0 5.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Diacylglycerol acyltransferase AAA_25 PF13481.6 RLN89600.1 - 0.095 12.3 0.1 41 3.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain RTP1_C1 PF10363.9 RLN89601.1 - 6.3e-27 94.0 1.3 2.6e-25 88.8 0.0 3.3 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 SNARE PF05739.19 RLN89601.1 - 4.1e-15 55.5 0.1 1e-14 54.3 0.1 1.7 1 0 0 1 1 1 1 SNARE domain RTP1_C2 PF10304.9 RLN89601.1 - 1.4e-06 27.9 0.8 1.4e-06 27.9 0.8 2.1 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 2 Syntaxin PF00804.25 RLN89601.1 - 0.012 15.4 0.2 0.012 15.4 0.2 3.6 4 0 0 4 4 4 0 Syntaxin DUF2951 PF11166.8 RLN89601.1 - 0.19 12.0 4.0 0.24 11.7 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) PHM7_cyt PF14703.6 RLN89601.1 - 0.34 11.1 3.7 1.9 8.7 0.2 3.4 1 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter HEAT_PBS PF03130.16 RLN89601.1 - 0.64 10.9 5.3 1.1 10.1 1.6 3.6 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat MCPsignal PF00015.21 RLN89601.1 - 1.2 8.9 7.8 0.086 12.6 1.1 2.5 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain HEAT_2 PF13646.6 RLN89601.1 - 4.3 7.8 11.0 0.15 12.4 0.5 3.9 4 0 0 4 4 4 0 HEAT repeats Aldo_ket_red PF00248.21 RLN89602.1 - 9.3e-47 159.6 0.0 1.3e-44 152.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Peptidase_M13 PF01431.21 RLN89602.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M13 Mannosyl_trans3 PF11051.8 RLN89605.1 - 2.8e-33 115.4 0.0 2.2e-31 109.2 0.0 2.2 1 1 0 1 1 1 1 Mannosyltransferase putative 2OG-FeII_Oxy PF03171.20 RLN89606.1 - 1.2e-24 86.7 0.0 2.2e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 RLN89606.1 - 4.1e-23 82.4 0.0 6.7e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal ABC2_membrane_3 PF12698.7 RLN89607.1 - 1.2e-17 64.1 17.4 1.8e-17 63.5 17.4 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein DUF2401 PF10287.9 RLN89608.1 - 1e-58 198.6 3.4 1e-58 198.6 3.4 2.1 2 1 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 RLN89608.1 - 2.9e-14 53.2 0.1 2.6e-13 50.2 0.0 2.6 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) Pec_lyase_C PF00544.19 RLN89609.1 - 5.6e-08 32.6 6.6 5.4e-07 29.4 0.3 2.4 1 1 0 2 2 2 2 Pectate lyase ABC_tran PF00005.27 RLN89610.1 - 9.8e-40 136.2 0.0 6.2e-24 85.1 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.7 RLN89610.1 - 1.2e-26 93.7 22.6 1.7e-26 93.2 22.6 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 RLN89610.1 - 2.2e-17 63.9 4.2 5.9e-07 29.6 0.2 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RLN89610.1 - 2e-09 37.2 0.1 3.3e-05 23.4 0.0 2.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RLN89610.1 - 0.0072 16.0 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain NB-ARC PF00931.22 RLN89610.1 - 0.013 14.7 0.6 1 8.5 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain ABC2_membrane PF01061.24 RLN89610.1 - 0.076 12.4 20.8 0.065 12.6 16.3 2.3 2 1 0 2 2 2 0 ABC-2 type transporter AAA_15 PF13175.6 RLN89610.1 - 0.12 12.1 0.0 11 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 RLN89610.1 - 0.18 12.3 0.0 0.43 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF5600 PF18150.1 RLN89611.1 - 1.8e-39 134.6 0.1 3.6e-39 133.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EHD_N PF16880.5 RLN89611.1 - 2.1e-16 59.5 1.6 3.6e-16 58.7 1.6 1.4 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 RLN89611.1 - 2.2e-16 60.4 0.0 3.3e-07 30.5 0.0 2.2 2 0 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 RLN89611.1 - 1.5e-09 37.9 0.0 3e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_4 PF12763.7 RLN89611.1 - 8.5e-09 35.3 0.0 2.3e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Roc PF08477.13 RLN89611.1 - 0.0017 18.6 0.0 1 9.6 0.0 2.7 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 RLN89611.1 - 0.04 13.4 0.0 0.14 11.6 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 RLN89611.1 - 0.074 12.6 0.0 4.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B DAO PF01266.24 RLN89612.1 - 7.7e-49 167.2 0.7 1e-48 166.8 0.7 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RLN89612.1 - 5.7e-05 23.3 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 RLN89612.1 - 0.00013 21.5 0.2 0.00021 20.8 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RLN89612.1 - 0.00086 18.6 0.2 0.0044 16.3 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 RLN89612.1 - 0.0012 18.2 0.1 0.0017 17.7 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 RLN89612.1 - 0.0054 15.9 2.4 0.0054 15.9 2.4 1.6 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.19 RLN89612.1 - 0.01 15.2 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 RLN89612.1 - 0.011 15.0 0.3 0.024 13.9 0.3 1.5 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 RLN89612.1 - 0.013 14.2 0.7 0.021 13.6 0.7 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 RLN89612.1 - 0.029 14.2 0.6 0.059 13.2 0.6 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 RLN89612.1 - 0.035 14.7 0.4 0.07 13.7 0.4 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RLN89612.1 - 0.036 13.3 0.3 0.062 12.5 0.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RLN89612.1 - 0.051 12.8 2.4 0.65 9.2 0.6 2.2 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 RLN89612.1 - 0.14 11.2 1.8 0.22 10.6 1.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A PDDEXK_2 PF12784.7 RLN89613.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease family transposase PX PF00787.24 RLN89613.1 - 0.076 13.0 0.0 0.26 11.3 0.0 2.0 1 1 0 1 1 1 0 PX domain TPD PF14811.6 RLN89620.1 - 7e-48 162.0 0.0 1.9e-47 160.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function TPD sequence-motif Glyco_trans_1_2 PF13524.6 RLN89620.1 - 0.16 12.4 0.4 0.88 10.0 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferases group 1 PX PF00787.24 RLN89621.1 - 0.02 14.9 1.2 0.055 13.4 1.1 1.9 1 1 0 1 1 1 0 PX domain Astacin PF01400.24 RLN89622.1 - 2.7e-22 79.3 9.8 2e-19 69.9 2.9 2.9 3 1 0 3 3 3 2 Astacin (Peptidase family M12A) Metallopep PF12044.8 RLN89622.1 - 0.0051 15.5 0.1 0.0085 14.7 0.1 1.3 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_3 PF13582.6 RLN89622.1 - 0.0074 16.8 0.5 0.02 15.4 0.0 2.2 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Retinal PF15449.6 RLN89622.1 - 0.024 12.4 0.8 0.033 12.0 0.8 1.1 1 0 0 1 1 1 0 Retinal protein Peptidase_M10 PF00413.24 RLN89622.1 - 0.071 12.9 6.8 0.24 11.3 4.7 2.5 2 1 0 2 2 2 0 Matrixin Cytomega_UL84 PF06284.11 RLN89622.1 - 0.42 9.0 1.9 0.6 8.5 1.9 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein FAM176 PF14851.6 RLN89622.1 - 0.75 9.5 6.1 0.12 12.0 2.2 1.7 2 0 0 2 2 2 0 FAM176 family Pkinase_Tyr PF07714.17 RLN89623.1 - 8.2e-60 202.3 0.0 7.1e-45 153.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN89623.1 - 1.7e-52 178.4 0.0 5.1e-39 134.2 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Arm PF00514.23 RLN89623.1 - 1.6e-18 66.0 26.0 0.00044 20.2 0.1 9.7 9 1 0 9 9 9 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN89623.1 - 3.3e-06 27.4 26.4 0.027 14.9 0.2 5.7 3 2 3 6 6 6 5 HEAT repeats HEAT_EZ PF13513.6 RLN89623.1 - 1.3e-05 25.6 33.1 0.002 18.6 2.1 7.1 5 3 1 7 7 7 2 HEAT-like repeat HEAT PF02985.22 RLN89623.1 - 0.0053 16.9 13.1 6.1 7.4 0.0 7.2 6 0 0 6 6 6 1 HEAT repeat UNC45-central PF11701.8 RLN89623.1 - 0.013 15.4 0.0 6.4 6.7 0.0 3.5 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central Kinase-like PF14531.6 RLN89623.1 - 0.026 13.8 0.0 1.5 8.1 0.0 2.8 3 0 0 3 3 3 0 Kinase-like MoaE PF02391.17 RLN89623.1 - 0.036 14.4 0.3 54 4.1 0.0 4.6 5 1 1 6 6 6 0 MoaE protein Kdo PF06293.14 RLN89623.1 - 0.047 13.0 0.0 3.4 7.0 0.0 2.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ACP_syn_III PF08545.10 RLN89623.1 - 0.22 11.4 2.1 17 5.4 0.2 3.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III cNMP_binding PF00027.29 RLN89624.1 - 2.5e-43 146.1 0.5 2.9e-12 46.5 0.0 4.5 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN89624.1 - 1.3e-22 80.3 39.9 3.9e-09 36.1 4.5 4.4 4 0 0 4 4 4 4 Ion transport protein Ion_trans_2 PF07885.16 RLN89624.1 - 1.6e-18 66.5 26.8 3.7e-08 33.2 4.8 5.9 5 0 0 5 5 5 4 Ion channel Ku PF02735.16 RLN89624.1 - 0.025 14.3 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Ku70/Ku80 beta-barrel domain TMEM192 PF14802.6 RLN89624.1 - 0.23 10.5 6.1 0.51 9.4 2.1 2.6 2 0 0 2 2 2 0 TMEM192 family Laminin_G_3 PF13385.6 RLN89625.1 - 1.5e-11 44.7 0.2 3.1e-11 43.7 0.2 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily ABC2_membrane PF01061.24 RLN89626.1 - 1.4e-26 93.2 26.9 1.8e-26 92.8 26.9 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN89626.1 - 5e-15 56.2 0.0 8.9e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 RLN89626.1 - 0.023 15.0 0.0 0.059 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_trans_N PF14510.6 RLN89626.1 - 0.04 14.5 0.3 0.14 12.7 0.0 2.0 2 0 0 2 2 2 0 ABC-transporter N-terminal MMR_HSR1 PF01926.23 RLN89626.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 RLN89626.1 - 0.11 12.2 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN89626.1 - 0.14 11.7 0.2 0.26 10.8 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 RLN89626.1 - 0.18 12.3 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PTR2 PF00854.21 RLN89627.1 - 2e-61 208.0 7.2 4e-61 207.0 7.2 1.5 1 1 0 1 1 1 1 POT family DUF5373 PF17343.2 RLN89627.1 - 2.7 7.8 8.6 0.092 12.6 1.1 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5373) DUF443 PF04276.12 RLN89627.1 - 8.1 6.2 12.0 17 5.2 4.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF443) SET PF00856.28 RLN89628.1 - 0.00023 21.6 3.0 0.00029 21.3 0.0 2.4 3 0 0 3 3 3 1 SET domain preSET_CXC PF18264.1 RLN89628.1 - 0.00026 21.4 24.5 0.00026 21.4 24.5 2.6 2 0 0 2 2 2 1 CXC domain RR_TM4-6 PF06459.12 RLN89628.1 - 1.3 8.7 11.2 1.7 8.4 1.9 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DJ-1_PfpI PF01965.24 RLN89629.1 - 2e-32 112.3 0.7 2.5e-32 111.9 0.7 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family CRM1_repeat PF18777.1 RLN89632.1 - 0.095 12.2 0.0 0.26 10.8 0.0 1.8 1 1 0 1 1 1 0 Chromosome region maintenance or exportin repeat Pkinase PF00069.25 RLN89633.1 - 3.6e-58 197.0 0.0 1.4e-57 195.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89633.1 - 6.2e-41 140.4 0.0 4.6e-25 88.4 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RLN89633.1 - 4.3e-06 26.2 0.0 0.0054 16.1 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 RLN89633.1 - 0.0081 15.0 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN89633.1 - 0.064 13.2 0.4 0.26 11.2 0.0 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family MOR2-PAG1_N PF14222.6 RLN89633.1 - 0.21 10.5 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Cell morphogenesis N-terminal VPS9 PF02204.18 RLN89634.1 - 1.5e-11 44.4 0.1 3.4e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain MIF PF01187.18 RLN89635.1 - 2.9e-14 53.4 0.1 3.3e-14 53.1 0.1 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 RLN89635.1 - 4.6e-08 32.9 0.0 1.1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Tautomerase enzyme TrmB PF01978.19 RLN89635.1 - 0.073 13.0 0.8 0.52 10.2 0.1 2.3 2 1 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Tautomerase_2 PF14552.6 RLN89635.1 - 0.14 12.3 0.0 0.71 10.0 0.0 1.8 2 0 0 2 2 2 0 Tautomerase enzyme 2OG-FeII_Oxy_3 PF13640.6 RLN89637.1 - 1.4e-15 57.9 0.1 4.8e-15 56.2 0.1 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily RskA PF10099.9 RLN89637.1 - 0.068 13.5 5.9 0.1 12.9 5.9 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF3523 PF12037.8 RLN89638.1 - 7e-42 143.6 28.9 1.2e-41 142.9 28.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 RLN89638.1 - 5.4e-22 78.6 0.0 1.4e-21 77.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN89638.1 - 1.4e-05 25.3 1.5 0.0015 18.9 0.0 3.4 3 2 0 3 3 3 1 AAA domain AAA_5 PF07728.14 RLN89638.1 - 2.9e-05 24.1 0.2 0.00031 20.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RLN89638.1 - 3e-05 23.8 0.0 0.0001 22.1 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 RLN89638.1 - 5.1e-05 22.7 0.2 0.00017 21.1 0.1 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zot PF05707.12 RLN89638.1 - 0.00021 21.0 0.3 0.3 10.7 0.0 3.2 3 0 0 3 3 3 1 Zonular occludens toxin (Zot) AAA_16 PF13191.6 RLN89638.1 - 0.00051 20.5 0.0 0.00051 20.5 0.0 4.4 2 2 1 3 3 2 1 AAA ATPase domain AAA_33 PF13671.6 RLN89638.1 - 0.00072 19.7 0.0 0.00072 19.7 0.0 3.3 2 1 0 2 2 1 1 AAA domain AAA_3 PF07726.11 RLN89638.1 - 0.0025 17.7 0.2 0.013 15.3 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RLN89638.1 - 0.0076 16.8 0.0 0.0076 16.8 0.0 3.0 2 2 0 2 2 1 1 AAA domain AAA_24 PF13479.6 RLN89638.1 - 0.0079 15.9 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 RLN89638.1 - 0.0095 15.9 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain TsaE PF02367.17 RLN89638.1 - 0.015 15.3 0.1 0.1 12.6 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 RLN89638.1 - 0.023 15.1 0.1 0.023 15.1 0.1 3.2 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RLN89638.1 - 0.042 13.4 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region MRF_C1 PF13887.6 RLN89638.1 - 0.045 12.9 0.3 0.25 10.5 0.0 2.3 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 RNA_helicase PF00910.22 RLN89638.1 - 0.049 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 RLN89638.1 - 0.085 12.9 0.0 0.26 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RLN89638.1 - 0.14 11.7 5.7 0.36 10.4 0.0 3.3 2 2 0 3 3 3 0 AAA domain AAA_11 PF13086.6 RLN89638.1 - 0.14 11.9 0.0 0.14 11.9 0.0 2.8 2 1 0 2 2 1 0 AAA domain PHZA_PHZB PF03284.13 RLN89638.1 - 0.23 11.1 0.8 0.72 9.5 0.0 2.0 2 0 0 2 2 2 0 Phenazine biosynthesis protein A/B ADH_N PF08240.12 RLN89639.1 - 4.4e-24 84.5 2.8 4.4e-24 84.5 2.8 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN89639.1 - 1.3e-14 54.3 0.0 2.3e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN89639.1 - 0.00016 21.1 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN89639.1 - 0.00043 19.7 0.0 0.00073 18.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 RLN89639.1 - 0.024 15.2 0.0 0.045 14.3 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 RLN89639.1 - 0.072 13.0 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_2 PF03446.15 RLN89639.1 - 0.078 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 RLN89639.1 - 0.085 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Oxidored_FMN PF00724.20 RLN89640.1 - 3.7e-74 250.0 0.0 4.8e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PGM1_C PF18105.1 RLN89640.1 - 0.26 10.8 1.8 1.1 8.8 0.1 2.5 2 0 0 2 2 2 0 PGM1 C-terminal domain zf-RING_2 PF13639.6 RLN89641.1 - 1e-06 28.9 3.7 1e-06 28.9 3.7 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN89641.1 - 6e-06 26.0 5.6 6e-06 26.0 5.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN89641.1 - 8.8e-06 25.9 1.2 8.8e-06 25.9 1.2 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RLN89641.1 - 2e-05 24.5 3.7 4.5e-05 23.3 3.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RLN89641.1 - 0.0001 22.1 4.6 0.00024 20.9 4.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN89641.1 - 0.00035 20.3 0.7 0.00082 19.1 0.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 RLN89641.1 - 0.0034 17.4 3.2 0.007 16.4 3.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RLN89641.1 - 0.019 14.8 2.0 0.05 13.5 2.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 RLN89641.1 - 0.044 13.7 2.9 0.11 12.4 2.9 1.7 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.8 RLN89641.1 - 0.049 13.4 2.5 0.19 11.6 1.1 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 RLN89641.1 - 0.05 13.6 0.4 0.16 12.0 0.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PX PF00787.24 RLN89641.1 - 0.095 12.7 0.0 0.21 11.6 0.0 1.7 1 1 0 1 1 1 0 PX domain Zn_ribbon_17 PF17120.5 RLN89641.1 - 0.14 11.8 1.4 0.53 10.0 1.4 1.9 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 RLN89641.1 - 0.25 11.4 3.8 0.71 10.0 3.8 1.9 1 0 0 1 1 1 0 Zinc-finger Prok-RING_4 PF14447.6 RLN89641.1 - 4.3 7.3 7.5 1.3 8.9 3.8 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 ECH_1 PF00378.20 RLN89642.1 - 1.8e-36 125.7 0.1 2.5e-36 125.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RLN89642.1 - 1.7e-22 80.4 0.2 4.5e-22 79.0 0.2 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ACBP PF00887.19 RLN89642.1 - 6.3e-22 77.6 0.0 1.1e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Metallophos PF00149.28 RLN89643.1 - 1.5e-15 58.2 1.7 7.9e-15 55.9 2.3 1.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RLN89643.1 - 2.5e-06 27.8 0.0 5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain P120R PF08062.11 RLN89644.1 - 0.45 10.9 14.5 0.36 11.2 9.3 2.8 2 1 0 2 2 2 0 P120R (NUC006) repeat DUF2489 PF10675.9 RLN89644.1 - 3 7.8 13.5 80 3.2 12.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2489) DDE_3 PF13358.6 RLN89645.1 - 0.054 13.2 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF659 PF04937.15 RLN89646.1 - 0.021 14.7 0.1 0.033 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 RLN89646.1 - 0.068 13.0 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF1180 PF06679.12 RLN89647.1 - 0.018 15.4 0.2 0.026 14.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4038 PF13204.6 RLN89648.1 - 1e-25 91.1 0.0 1.1e-25 90.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) BT1 PF03092.16 RLN89649.1 - 1.8e-09 36.4 16.7 2.2e-09 36.1 3.2 2.9 2 1 1 3 3 3 2 BT1 family DUF3975 PF13126.6 RLN89649.1 - 0.09 13.2 1.6 21 5.6 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3975) Holin_2-3 PF13272.6 RLN89649.1 - 0.4 11.0 4.8 0.11 12.8 0.7 2.3 2 0 0 2 2 2 0 Putative 2/3 transmembrane domain holin BT1 PF03092.16 RLN89650.1 - 3.5e-11 42.1 7.3 3.5e-11 42.1 7.3 2.5 2 1 1 3 3 3 1 BT1 family ETM PF17577.2 RLN89650.1 - 0.07 13.7 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 ECORI-T site ABC_tran PF00005.27 RLN89651.1 - 3.9e-28 98.7 0.0 7e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 RLN89651.1 - 2.6e-16 59.7 27.0 1.3e-15 57.4 27.0 2.1 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 RLN89651.1 - 1.8e-07 31.3 0.0 0.0053 16.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 RLN89651.1 - 0.0014 18.1 26.2 0.051 13.0 21.3 2.5 2 0 0 2 2 2 2 ABC-2 type transporter RsgA_GTPase PF03193.16 RLN89651.1 - 0.0015 18.4 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 RLN89651.1 - 0.0023 18.4 0.1 0.0044 17.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 RLN89651.1 - 0.015 15.0 0.1 0.037 13.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 RLN89651.1 - 0.031 14.0 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 RLN89651.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_30 PF13604.6 RLN89651.1 - 0.14 11.9 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 RLN89651.1 - 0.16 10.7 0.0 0.32 9.8 0.0 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) ABC2_membrane_5 PF13346.6 RLN89651.1 - 0.7 9.4 20.3 1.4 8.5 20.3 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Aa_trans PF01490.18 RLN89652.1 - 7.5e-44 150.1 11.6 1.4e-43 149.2 11.6 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Flp1_like PF16982.5 RLN89652.1 - 0.0096 15.3 3.5 0.041 13.3 3.5 2.0 1 0 0 1 1 1 1 Putative Flagellin, Flp1-like, domain DUF3675 PF12428.8 RLN89652.1 - 0.47 11.0 6.8 0.42 11.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3675) Orf78 PF06024.12 RLN89652.1 - 1.3 9.4 3.4 12 6.3 0.1 3.0 3 0 0 3 3 3 0 Orf78 (ac78) Helitron_like_N PF14214.6 RLN89653.1 - 5e-21 75.8 0.0 1.4e-20 74.3 0.0 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 RLN89653.1 - 3.1e-20 72.7 1.9 1.3e-18 67.3 0.8 2.7 2 1 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.6 RLN89653.1 - 1.8e-14 53.9 0.1 2.1e-13 50.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 RLN89653.1 - 4.4e-06 27.1 2.9 8.4e-06 26.2 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 RLN89653.1 - 0.066 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SelR PF01641.18 RLN89654.1 - 3e-40 137.1 0.1 4.6e-40 136.5 0.1 1.3 1 1 0 1 1 1 1 SelR domain Trehalose_PPase PF02358.16 RLN89655.1 - 5e-06 25.8 0.0 6.4e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Ribosomal_L32p PF01783.23 RLN89656.1 - 8.2e-11 42.0 3.1 1.1e-10 41.6 3.1 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family Rad21_Rec8_N PF04825.13 RLN89656.1 - 0.081 13.1 0.2 0.11 12.6 0.2 1.4 1 1 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein Ribonucleas_3_3 PF14622.6 RLN89657.1 - 9e-44 148.7 0.1 7.9e-21 74.5 0.0 3.3 3 0 0 3 3 3 3 Ribonuclease-III-like Ribonuclease_3 PF00636.26 RLN89657.1 - 2.6e-36 124.4 0.4 4e-18 66.0 0.1 2.7 2 0 0 2 2 2 2 Ribonuclease III domain dsrm PF00035.26 RLN89657.1 - 0.14 12.9 0.1 0.32 11.7 0.1 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif Torus PF16131.5 RLN89658.1 - 5.9e-09 36.6 0.0 1.2e-08 35.6 0.0 1.6 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 RLN89658.1 - 5.3e-06 26.3 1.5 5.3e-06 26.3 1.5 2.1 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 RLN89658.1 - 1e-05 25.3 2.3 1e-05 25.3 2.3 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 RLN89658.1 - 0.0051 16.6 2.2 0.01 15.6 2.2 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger FYVE PF01363.21 RLN89658.1 - 0.0085 16.2 1.2 0.0085 16.2 1.2 2.2 3 0 0 3 3 3 1 FYVE zinc finger zf-CCCH_2 PF14608.6 RLN89658.1 - 0.031 14.8 0.8 0.072 13.6 0.8 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Zn_ribbon_recom PF13408.6 RLN89658.1 - 5.2 7.7 10.4 0.26 11.8 3.5 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain SRP54 PF00448.22 RLN89659.1 - 1.8e-75 252.9 0.1 3.5e-75 251.9 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 RLN89659.1 - 3.8e-28 98.0 1.0 3.8e-28 98.0 1.0 3.4 3 0 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 RLN89659.1 - 1.3e-17 63.8 2.4 2.6e-17 62.8 2.4 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain SRPRB PF09439.10 RLN89659.1 - 5.4e-05 22.7 1.0 0.6 9.5 0.0 3.7 2 2 1 3 3 3 2 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 RLN89659.1 - 6.3e-05 23.4 0.0 0.0002 21.8 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 RLN89659.1 - 9.2e-05 22.6 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 RLN89659.1 - 0.00045 19.9 0.2 0.0071 16.0 0.2 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 RLN89659.1 - 0.00074 19.3 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 RLN89659.1 - 0.0014 17.6 0.0 0.014 14.4 0.0 2.4 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2209 PF09974.9 RLN89659.1 - 0.0016 18.7 0.1 0.0039 17.5 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) AAA_22 PF13401.6 RLN89659.1 - 0.015 15.6 0.0 0.044 14.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 RLN89659.1 - 0.024 14.5 0.0 0.088 12.7 0.0 2.0 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MMR_HSR1 PF01926.23 RLN89659.1 - 0.032 14.3 0.2 0.6 10.2 0.2 2.9 2 2 1 3 3 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 RLN89659.1 - 0.033 14.4 0.0 0.072 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 RLN89659.1 - 0.034 14.0 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase MobB PF03205.14 RLN89659.1 - 0.042 13.8 0.0 0.098 12.6 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.23 RLN89659.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 RLN89659.1 - 0.065 13.2 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RLN89659.1 - 0.072 13.4 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 RLN89659.1 - 0.073 13.5 0.2 0.43 11.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 RLN89659.1 - 0.17 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Ion_trans PF00520.31 RLN89660.1 - 7.3e-47 159.7 35.6 9.6e-24 83.9 12.1 2.2 2 0 0 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 RLN89660.1 - 4.3e-20 71.5 19.0 4.5e-12 45.8 6.0 2.9 2 0 0 2 2 2 2 Ion channel cNMP_binding PF00027.29 RLN89660.1 - 6.3e-15 55.0 0.1 1.4e-06 28.2 0.0 3.4 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Ank_4 PF13637.6 RLN89661.1 - 3.3e-12 46.7 0.6 1.4e-06 28.7 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN89661.1 - 3.9e-10 40.2 0.1 0.0013 19.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN89661.1 - 1.2e-06 28.7 0.6 0.0098 16.2 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN89661.1 - 1.7e-06 27.9 0.4 0.015 15.7 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 RLN89661.1 - 3.3e-06 27.3 0.5 0.17 12.4 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat PDZ_6 PF17820.1 RLN89661.1 - 0.11 12.4 2.0 0.39 10.6 0.1 2.8 3 0 0 3 3 3 0 PDZ domain DHHC PF01529.20 RLN89662.1 - 2.3e-18 66.6 8.1 2.3e-18 66.6 8.1 2.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF4199 PF13858.6 RLN89662.1 - 6 7.2 8.6 7.3 7.0 0.2 2.7 2 2 1 3 3 3 0 Protein of unknown function (DUF4199) Cellulase PF00150.18 RLN89663.1 - 1.7e-18 67.1 0.1 2.2e-18 66.7 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.25 RLN89664.1 - 2.6e-60 204.0 0.0 2.4e-40 138.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89664.1 - 1.4e-28 99.9 0.0 1.1e-23 83.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase cNMP_binding PF00027.29 RLN89664.1 - 3.1e-21 75.2 0.0 1.1e-12 47.8 0.0 3.8 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 RLN89664.1 - 4.8e-08 32.7 0.0 0.0001 21.8 0.0 2.6 2 1 0 2 2 2 2 Kinase-like APH PF01636.23 RLN89664.1 - 1.7e-05 24.9 0.1 4.5e-05 23.5 0.1 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN89664.1 - 5.5e-05 22.6 0.0 0.00013 21.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN89664.1 - 0.00017 20.5 0.0 0.00031 19.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 RLN89664.1 - 0.0022 17.6 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 RLN89664.1 - 0.006 16.2 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Aldo_ket_red PF00248.21 RLN89665.1 - 8.2e-07 28.5 0.0 1.4e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family ANAPC4 PF12896.7 RLN89667.1 - 8.8e-09 35.2 0.3 1.3e-08 34.6 0.3 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Astro_capsid_p PF12226.8 RLN89667.1 - 0.034 13.3 1.5 0.048 12.8 1.5 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Myc_N PF01056.18 RLN89667.1 - 0.087 12.7 0.3 0.15 11.9 0.1 1.5 2 0 0 2 2 2 0 Myc amino-terminal region DUF4632 PF15451.6 RLN89667.1 - 1 9.5 5.5 4.8 7.3 3.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) ANAPC4_WD40 PF12894.7 RLN89668.1 - 1.1e-11 44.8 0.0 1.2e-10 41.5 0.0 2.7 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain ANAPC4 PF12896.7 RLN89668.1 - 1.7e-06 27.7 0.0 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 HrpE PF06188.12 RLN89668.1 - 0.003 17.5 0.2 0.0057 16.6 0.2 1.4 1 0 0 1 1 1 1 HrpE/YscL/FliH and V-type ATPase subunit E Amino_oxidase PF01593.24 RLN89669.1 - 8.2e-129 430.8 0.0 1.5e-71 242.1 0.0 2.0 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RLN89669.1 - 1.1e-22 80.1 2.0 2.1e-10 40.7 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 RLN89669.1 - 2e-16 60.4 2.6 0.0004 20.4 0.0 4.8 5 0 0 5 5 5 4 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 RLN89669.1 - 2.5e-10 40.1 0.6 0.021 14.1 0.0 4.1 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RLN89669.1 - 6.4e-10 39.1 6.6 0.00019 21.2 2.1 3.5 2 2 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 RLN89669.1 - 1.6e-06 28.5 0.6 0.015 15.9 0.1 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RLN89669.1 - 2.4e-06 27.2 1.7 0.013 14.9 0.0 3.2 4 0 0 4 4 4 2 FAD dependent oxidoreductase MCRA PF06100.11 RLN89669.1 - 3.8e-06 26.0 0.7 0.0084 15.0 0.1 2.1 2 0 0 2 2 2 2 MCRA family Lycopene_cycl PF05834.12 RLN89669.1 - 3.3e-05 23.1 6.9 0.96 8.4 0.4 4.2 4 0 0 4 4 4 2 Lycopene cyclase protein HI0933_like PF03486.14 RLN89669.1 - 4.5e-05 22.3 4.7 0.13 10.9 0.3 4.0 4 0 0 4 4 4 2 HI0933-like protein Pyr_redox_3 PF13738.6 RLN89669.1 - 0.00037 19.8 3.5 6.1 6.0 0.2 4.0 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 RLN89669.1 - 0.0014 18.0 1.4 0.18 11.0 0.2 2.4 2 0 0 2 2 2 1 Thi4 family DUF3040 PF11239.8 RLN89669.1 - 0.0021 18.3 2.8 0.091 13.0 0.0 3.4 3 0 0 3 3 2 1 Protein of unknown function (DUF3040) FAD_binding_3 PF01494.19 RLN89669.1 - 0.0031 16.8 4.1 0.33 10.1 0.3 2.5 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 RLN89669.1 - 0.0034 16.5 8.0 0.069 12.2 1.0 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 RLN89669.1 - 0.0037 16.4 10.0 0.04 13.0 1.7 2.5 2 0 0 2 2 2 2 FAD binding domain KH_7 PF17214.3 RLN89669.1 - 0.011 15.7 0.0 5.5 7.0 0.0 2.5 2 0 0 2 2 2 0 KH domain AlaDh_PNT_C PF01262.21 RLN89669.1 - 0.012 14.9 4.2 0.38 10.0 1.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Myosin_N PF02736.19 RLN89669.1 - 0.038 13.8 0.4 3.8 7.4 0.1 2.8 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Shikimate_DH PF01488.20 RLN89669.1 - 0.048 13.7 0.1 7.1 6.7 0.1 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF5609 PF18429.1 RLN89669.1 - 0.053 13.3 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5609) Trp_halogenase PF04820.14 RLN89669.1 - 0.36 9.6 2.4 1.5 7.6 0.2 2.3 2 0 0 2 2 2 0 Tryptophan halogenase F420_oxidored PF03807.17 RLN89669.1 - 0.42 11.2 1.5 14 6.4 0.1 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Fringe PF02434.16 RLN89670.1 - 9.5e-10 38.3 0.1 1.6e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 RLN89670.1 - 1.9e-05 24.6 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase UQ_con PF00179.26 RLN89671.1 - 0.032 13.9 0.3 0.11 12.1 0.3 1.9 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme GCV_T PF01571.21 RLN89672.1 - 2.2e-13 50.2 0.1 3.6e-13 49.5 0.1 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Pkinase PF00069.25 RLN89673.1 - 3.6e-28 98.7 0.0 4.1e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89673.1 - 1.2e-26 93.5 0.0 1.5e-26 93.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN89673.1 - 0.00034 19.5 0.0 0.00041 19.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 RLN89673.1 - 0.011 15.3 0.1 0.016 14.8 0.1 1.1 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 RLN89673.1 - 0.023 14.6 0.3 0.033 14.1 0.3 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN89673.1 - 0.13 11.6 0.3 0.19 11.1 0.3 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IQ PF00612.27 RLN89674.1 - 0.031 14.1 8.2 0.46 10.4 1.5 3.4 3 0 0 3 3 3 0 IQ calmodulin-binding motif Chorismate_bind PF00425.18 RLN89675.1 - 1.2e-95 320.0 0.0 1.8e-95 319.4 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 RLN89675.1 - 6.4e-28 97.7 0.0 7.2e-27 94.3 0.0 2.6 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region GRDA PF04723.14 RLN89676.1 - 0.052 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A CbiD PF01888.17 RLN89676.1 - 0.06 12.6 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 CbiD Anillin PF08174.11 RLN89677.1 - 0.086 13.3 0.0 0.26 11.7 0.0 1.8 1 0 0 1 1 1 0 Cell division protein anillin NADHdh_A3 PF14987.6 RLN89678.1 - 0.00067 19.9 0.0 0.00093 19.4 0.0 1.3 1 0 0 1 1 1 1 NADH dehydrogenase 1 alpha subcomplex subunit 3 Pkinase PF00069.25 RLN89681.1 - 7.2e-47 160.0 0.0 9.4e-44 149.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89681.1 - 4.5e-25 88.4 0.0 6.1e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN89681.1 - 2e-06 26.8 0.0 3.1e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN89681.1 - 3.7e-05 23.8 0.2 0.00051 20.0 0.2 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RLN89681.1 - 0.00011 21.6 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 RLN89681.1 - 0.001 18.7 0.0 0.024 14.3 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 RLN89681.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bacteriocin_IIi PF11758.8 RLN89681.1 - 0.21 11.5 0.1 0.42 10.5 0.1 1.4 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin AIRS_C PF02769.22 RLN89682.1 - 1.2e-22 80.7 0.0 1.8e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 RLN89682.1 - 1.2e-09 38.6 0.1 2.9e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain PPS_PS PF02006.16 RLN89682.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Phosphopantothenate/pantothenate synthetase Syntaxin_2 PF14523.6 RLN89683.1 - 8.9e-16 58.1 7.6 1e-15 58.0 1.2 2.2 2 0 0 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.25 RLN89683.1 - 0.00016 21.5 6.3 0.028 14.1 1.5 2.3 2 0 0 2 2 2 2 Syntaxin Synaptobrevin PF00957.21 RLN89683.1 - 0.00095 18.9 1.1 0.00095 18.9 1.1 2.4 3 0 0 3 3 2 1 Synaptobrevin SNARE PF05739.19 RLN89683.1 - 0.0013 18.7 5.3 0.0013 18.7 5.3 2.1 2 1 0 2 2 1 1 SNARE domain AAA_13 PF13166.6 RLN89683.1 - 0.0018 17.1 2.8 0.0054 15.4 0.2 2.0 2 0 0 2 2 2 1 AAA domain CorA PF01544.18 RLN89683.1 - 0.0023 17.3 1.4 0.0024 17.2 0.1 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Spectrin PF00435.21 RLN89683.1 - 0.021 15.3 4.6 1.4 9.4 0.3 3.2 3 0 0 3 3 3 0 Spectrin repeat DUF3802 PF12290.8 RLN89683.1 - 0.06 13.9 0.9 0.87 10.1 0.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3802) DUF3683 PF12447.8 RLN89683.1 - 0.24 11.5 1.3 1.5 9.0 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3683) HisKA_3 PF07730.13 RLN89683.1 - 0.28 11.7 5.0 13 6.3 0.1 3.3 3 1 0 3 3 3 0 Histidine kinase Yuri_gagarin PF15934.5 RLN89683.1 - 0.3 10.9 5.3 0.18 11.6 1.3 2.4 2 1 0 2 2 2 0 Yuri gagarin COG2 PF06148.11 RLN89683.1 - 0.31 11.1 2.5 3.1 7.9 0.3 2.5 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4890 PF16231.5 RLN89683.1 - 0.65 10.5 3.1 0.34 11.4 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4890) SKA2 PF16740.5 RLN89683.1 - 1.8 8.4 6.2 4.8 7.0 0.2 3.0 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF2203 PF09969.9 RLN89683.1 - 2.2 9.0 5.3 35 5.1 0.2 2.7 1 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Sec34 PF04136.15 RLN89683.1 - 3.1 7.7 7.3 3.5 7.5 0.1 3.1 3 1 0 3 3 3 0 Sec34-like family DUF16 PF01519.16 RLN89683.1 - 5 7.7 7.2 6.9 7.2 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function DUF16 LRRFIP PF09738.9 RLN89683.1 - 5.3 6.4 9.6 0.57 9.6 1.2 2.3 1 1 0 2 2 2 0 LRRFIP family Seryl_tRNA_N PF02403.22 RLN89683.1 - 5.4 7.3 8.4 3.1 8.0 0.9 3.1 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.12 RLN89683.1 - 8 6.5 9.9 7.7 6.5 0.6 3.4 2 1 1 3 3 3 0 Laminin Domain II Glyco_hydro_35 PF01301.19 RLN89684.1 - 2.5e-73 247.5 0.5 3.3e-73 247.1 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 GHD PF17834.1 RLN89684.1 - 4.6e-06 26.6 0.0 1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Beta-sandwich domain in beta galactosidase BetaGal_dom4_5 PF13364.6 RLN89684.1 - 0.001 19.6 0.0 1.5 9.4 0.0 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain Ank_5 PF13857.6 RLN89686.1 - 9.1e-19 67.3 3.8 8.7e-06 25.9 0.1 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN89686.1 - 7.9e-18 64.8 0.7 7.5e-05 23.2 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN89686.1 - 2.7e-15 56.5 0.1 0.0026 18.3 0.0 5.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN89686.1 - 7.7e-12 44.3 0.6 0.099 13.3 0.0 6.5 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 RLN89686.1 - 7.2e-07 29.4 0.1 0.38 11.3 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat TPR_12 PF13424.6 RLN89686.1 - 9.2e-06 25.9 0.3 0.0023 18.2 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-B_box PF00643.24 RLN89686.1 - 0.00042 20.4 11.5 0.00084 19.4 11.5 1.4 1 0 0 1 1 1 1 B-box zinc finger TPR_10 PF13374.6 RLN89686.1 - 0.0058 16.5 2.8 2.8 7.9 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat Siva PF05458.12 RLN89686.1 - 0.046 13.4 2.8 0.1 12.3 2.8 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) RGS PF00615.19 RLN89686.1 - 0.07 13.4 0.1 0.64 10.3 0.1 2.7 1 1 0 1 1 1 0 Regulator of G protein signaling domain Alpha-mann_mid PF09261.11 RLN89686.1 - 0.45 10.7 4.5 0.28 11.4 0.3 2.7 2 0 0 2 2 2 0 Alpha mannosidase middle domain Homeobox_KN PF05920.11 RLN89687.1 - 2.2e-16 59.5 0.5 4.6e-16 58.4 0.5 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 RLN89687.1 - 6.2e-11 42.0 2.5 1e-10 41.3 1.2 1.9 2 0 0 2 2 2 1 Homeodomain Homez PF11569.8 RLN89687.1 - 0.0001 21.7 0.2 0.0054 16.2 0.1 2.5 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez DUF5341 PF17276.2 RLN89687.1 - 0.0023 18.1 0.9 0.089 13.0 0.5 2.2 1 1 1 2 2 2 1 Family of unknown function (DUF5341) FaeA PF04703.12 RLN89687.1 - 0.078 13.4 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 FaeA-like protein HTH_Tnp_ISL3 PF13542.6 RLN89687.1 - 0.33 10.4 3.2 8.8 5.8 0.0 3.6 4 0 0 4 4 4 0 Helix-turn-helix domain of transposase family ISL3 Laminin_G_3 PF13385.6 RLN89689.1 - 2.7e-12 47.1 2.3 5.8e-10 39.5 0.3 3.4 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily Laminin_B PF00052.18 RLN89689.1 - 3.7e-05 23.6 0.0 0.00016 21.6 0.0 2.1 2 0 0 2 2 2 1 Laminin B (Domain IV) Calx-beta PF03160.14 RLN89689.1 - 4.3e-05 23.6 2.7 4.9e-05 23.4 0.1 2.6 2 0 0 2 2 2 1 Calx-beta domain Pentaxin PF00354.17 RLN89689.1 - 6.9e-05 22.6 0.0 0.033 13.9 0.0 4.0 4 0 0 4 4 4 1 Pentaxin family ACPS PF01648.20 RLN89691.1 - 8.9e-14 51.6 0.0 1e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ribosomal_L7Ae PF01248.26 RLN89692.1 - 2.2e-22 78.6 0.0 2.4e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family IF-2B PF01008.17 RLN89693.1 - 3.2e-38 131.6 3.0 5.4e-24 84.9 1.3 3.4 2 2 0 2 2 2 2 Initiation factor 2 subunit family DUF2723 PF11028.8 RLN89694.1 - 3.8e-12 46.5 0.5 1.2e-11 44.8 0.3 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2723) Peptidase_A24 PF01478.18 RLN89694.1 - 0.52 10.7 4.5 0.66 10.4 1.6 2.4 2 1 0 2 2 2 0 Type IV leader peptidase family RRP7 PF12923.7 RLN89696.1 - 5.1e-24 84.7 12.4 1.5e-18 67.0 3.1 2.2 2 0 0 2 2 2 2 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 RLN89696.1 - 0.0015 18.3 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 RLN89696.1 - 0.0049 16.7 0.0 0.021 14.6 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 RLN89697.1 - 3.1e-06 26.7 0.0 3.6e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Acetyltransf_1 PF00583.25 RLN89699.1 - 6.1e-13 49.0 0.0 7.5e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RLN89699.1 - 5.4e-10 39.3 0.0 7.6e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN89699.1 - 5.6e-09 36.3 0.0 7.9e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN89699.1 - 0.00052 19.9 0.0 0.00083 19.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 RLN89699.1 - 0.00062 19.9 0.0 0.00072 19.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 RLN89699.1 - 0.067 13.3 0.0 0.085 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CBM_1 PF00734.18 RLN89701.1 - 1.8e-31 107.8 48.2 1.4e-10 40.9 8.5 6.0 5 1 0 5 5 5 5 Fungal cellulose binding domain Toxin_7 PF05980.12 RLN89701.1 - 7.6 6.9 16.0 23 5.3 1.0 4.2 4 0 0 4 4 4 0 Toxin 7 Ras PF00071.22 RLN89702.1 - 5.3e-42 143.2 0.1 5.4e-38 130.1 0.1 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RLN89702.1 - 1.9e-23 83.0 0.1 6.4e-19 68.3 0.0 2.3 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN89702.1 - 6.1e-07 29.1 0.1 6.1e-06 25.8 0.0 2.0 1 1 1 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RLN89702.1 - 1.3e-05 25.2 0.4 0.019 14.9 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 RLN89702.1 - 7.4e-05 22.3 0.2 0.0033 16.9 0.0 2.1 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 RLN89702.1 - 0.00018 21.5 0.0 0.00025 21.1 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RLN89702.1 - 0.00037 20.9 0.0 0.00053 20.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 RLN89702.1 - 0.0024 17.2 0.0 0.019 14.3 0.0 1.9 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 RLN89702.1 - 0.0089 16.5 0.1 0.015 15.8 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 RLN89702.1 - 0.015 15.0 0.0 0.37 10.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 RLN89702.1 - 0.021 14.0 0.0 0.036 13.2 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit AAA_7 PF12775.7 RLN89702.1 - 0.051 13.1 0.1 0.08 12.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 RLN89702.1 - 0.062 12.7 0.0 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 RLN89702.1 - 0.095 11.8 0.1 0.28 10.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 RLN89702.1 - 0.096 13.0 0.1 0.35 11.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 RLN89702.1 - 0.098 12.7 0.0 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DAP3 PF10236.9 RLN89702.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 MCM PF00493.23 RLN89702.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain Hpr_kinase_C PF07475.12 RLN89702.1 - 0.17 11.4 0.0 0.44 10.1 0.0 1.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain SmpB PF01668.18 RLN89703.1 - 1.2e-13 51.2 0.0 8e-09 35.5 0.0 2.1 2 0 0 2 2 2 2 SmpB protein Tub PF01167.18 RLN89704.1 - 6e-28 98.2 0.0 7.4e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Tub family RSN1_7TM PF02714.15 RLN89705.1 - 3.3e-07 29.9 4.5 3.3e-07 29.9 4.5 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 RLN89705.1 - 0.0006 20.1 11.0 0.0033 17.7 2.2 4.2 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter RRM_1 PF00076.22 RLN89705.1 - 0.047 13.5 0.0 4.1 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_1 PF00583.25 RLN89706.1 - 2.3e-18 66.6 0.0 2.7e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RLN89706.1 - 4.9e-14 52.4 0.0 6.7e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN89706.1 - 3.1e-12 46.8 0.0 4.5e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 RLN89706.1 - 1.2e-05 25.6 0.0 1.4e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN89706.1 - 1.6e-05 24.8 0.0 2.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 RLN89706.1 - 2.4e-05 25.0 0.1 3e-05 24.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 RLN89706.1 - 0.00011 22.4 0.1 0.00015 22.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GEN1_C PF18380.1 RLN89707.1 - 0.62 11.0 4.0 2.2 9.2 0.8 2.2 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain FAM176 PF14851.6 RLN89707.1 - 5 6.8 10.2 1.2 8.8 3.0 2.2 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.6 RLN89707.1 - 5.3 7.5 7.0 2.7 8.4 0.4 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal OB_RNB PF08206.11 RLN89708.1 - 4.5e-05 23.0 0.0 20 5.0 0.0 4.9 1 1 4 5 5 5 2 Ribonuclease B OB domain PDR_CDR PF06422.12 RLN89708.1 - 0.0079 16.1 0.1 85 3.2 0.0 4.1 1 1 3 4 4 4 0 CDR ABC transporter Auxin_resp PF06507.13 RLN89708.1 - 0.099 12.9 0.4 25 5.2 0.0 2.9 1 1 3 4 4 4 0 Auxin response factor DUF2807 PF10988.8 RLN89708.1 - 0.21 11.3 7.1 2.5 7.9 0.7 2.2 1 1 1 2 2 2 0 Putative auto-transporter adhesin, head GIN domain DUF4245 PF14030.6 RLN89708.1 - 0.37 10.8 2.2 3.7 7.5 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4245) Kinesin PF00225.23 RLN89709.1 - 4.3e-118 394.0 0.0 1e-117 392.8 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN89709.1 - 5.4e-27 94.6 0.1 4.4e-26 91.6 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding DUF812 PF05667.11 RLN89709.1 - 0.018 14.0 30.6 0.025 13.5 30.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Kinesin_assoc PF16183.5 RLN89709.1 - 0.093 12.9 12.5 0.027 14.6 5.5 3.1 2 1 1 3 3 3 0 Kinesin-associated AAA_22 PF13401.6 RLN89709.1 - 0.83 9.9 0.0 0.83 9.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain Carbpep_Y_N PF05388.11 RLN89709.1 - 5.7 7.5 8.2 3.3 8.3 4.3 2.3 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide Ank_2 PF12796.7 RLN89710.1 - 6.1e-63 209.4 1.2 5.3e-12 46.2 0.0 5.1 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN89710.1 - 8.2e-49 157.9 6.5 0.0019 18.5 0.0 10.3 10 0 0 10 10 10 10 Ankyrin repeat Ank_4 PF13637.6 RLN89710.1 - 6.1e-48 160.6 5.7 6.5e-09 36.2 0.0 7.2 4 1 3 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 RLN89710.1 - 1.1e-45 152.1 14.1 0.00048 20.4 0.0 10.3 10 0 0 10 10 10 10 Ankyrin repeat Ank_5 PF13857.6 RLN89710.1 - 1e-42 143.6 18.1 1.3e-06 28.6 0.1 10.4 4 3 7 11 11 11 10 Ankyrin repeats (many copies) DUF3107 PF11305.8 RLN89710.1 - 0.00094 19.4 0.1 1.1 9.6 0.0 3.2 4 0 0 4 4 4 2 Protein of unknown function (DUF3107) RsdA_SigD_bd PF16751.5 RLN89710.1 - 7.5 6.9 8.3 51 4.2 4.0 3.5 3 1 0 3 3 3 0 Anti-sigma-D factor RsdA to sigma factor binding region AAA PF00004.29 RLN89711.1 - 8.5e-08 32.7 0.5 2.4e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN89711.1 - 2.1e-07 31.5 0.3 2.7e-06 27.9 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RLN89711.1 - 0.00017 21.9 2.9 0.33 11.2 0.2 3.4 2 1 1 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 RLN89711.1 - 0.00026 20.8 0.2 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 RLN89711.1 - 0.00068 19.7 0.0 0.0037 17.3 0.1 2.3 2 0 0 2 2 1 1 AAA domain Bac_DnaA PF00308.18 RLN89711.1 - 0.0019 18.1 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein Rad17 PF03215.15 RLN89711.1 - 0.0053 16.7 0.0 0.032 14.2 0.0 2.0 1 1 1 2 2 2 1 Rad17 P-loop domain Cdc6_C PF09079.11 RLN89711.1 - 0.016 15.2 0.0 0.059 13.4 0.0 1.9 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain TniB PF05621.11 RLN89711.1 - 0.023 14.1 0.2 0.99 8.8 0.1 2.6 2 1 1 3 3 3 0 Bacterial TniB protein ATPase_2 PF01637.18 RLN89711.1 - 0.025 14.5 5.6 0.17 11.8 0.0 3.0 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 RLN89711.1 - 0.045 13.8 0.0 0.13 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Pox_D5 PF03288.16 RLN89711.1 - 0.074 13.5 0.0 32 5.1 0.0 3.4 3 0 0 3 3 3 0 Poxvirus D5 protein-like Leo1 PF04004.13 RLN89713.1 - 1.2e-36 126.1 1.2 1.2e-36 126.1 1.2 2.2 2 0 0 2 2 2 1 Leo1-like protein Thioredoxin_4 PF13462.6 RLN89713.1 - 0.2 11.8 7.3 0.41 10.8 1.2 2.4 2 0 0 2 2 2 0 Thioredoxin Ank_2 PF12796.7 RLN89714.1 - 6e-17 62.0 0.1 1.1e-08 35.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RLN89714.1 - 4.3e-15 55.4 0.6 3.7e-06 27.1 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 RLN89714.1 - 8.6e-13 47.2 0.1 6.6e-05 23.0 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RLN89714.1 - 1.1e-11 44.7 0.2 4.7e-06 26.8 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN89714.1 - 1.6e-11 44.5 0.0 5.7e-09 36.3 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) DUF2384 PF09722.10 RLN89714.1 - 0.014 15.4 1.1 0.65 10.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2384) Ank_2 PF12796.7 RLN89715.1 - 2e-48 162.9 0.9 2.4e-15 56.9 0.0 4.1 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN89715.1 - 1.4e-45 153.1 15.3 8.5e-10 39.0 0.1 7.0 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN89715.1 - 2.8e-33 110.2 3.7 8.9e-05 22.6 0.0 9.3 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 RLN89715.1 - 4e-31 106.7 9.5 3.1e-07 30.5 0.1 7.0 3 3 5 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 RLN89715.1 - 1.6e-30 104.1 15.6 4.2e-06 26.9 0.0 8.8 9 0 0 9 9 9 6 Ankyrin repeat DUF2384 PF09722.10 RLN89715.1 - 2.3 8.3 9.8 2.3 8.3 0.1 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2384) MPM1 PF17234.2 RLN89719.1 - 0.019 15.2 1.8 0.022 15.0 1.8 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 FANCD2OS PF15124.6 RLN89719.1 - 0.1 12.8 0.5 0.15 12.3 0.5 1.2 1 0 0 1 1 1 0 FANCD2 opposite strand protein Cytomega_UL84 PF06284.11 RLN89719.1 - 0.82 8.0 6.4 1.1 7.7 6.4 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein SelP_N PF04592.14 RLN89719.1 - 0.88 8.9 9.4 1.1 8.6 9.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FAM176 PF14851.6 RLN89719.1 - 2.4 7.8 5.6 3.3 7.3 5.6 1.3 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 RLN89719.1 - 3 6.0 11.6 3.3 5.9 11.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 RLN89719.1 - 3.6 6.7 5.7 4.1 6.5 5.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2046 PF09755.9 RLN89720.1 - 1.2e-30 106.8 39.0 7.7e-30 104.2 38.6 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Val_tRNA-synt_C PF10458.9 RLN89720.1 - 0.048 14.0 1.9 0.048 14.0 1.9 5.6 3 1 2 6 6 6 0 Valyl tRNA synthetase tRNA binding arm Baculo_PEP_C PF04513.12 RLN89720.1 - 0.17 11.9 11.7 2.3 8.3 7.6 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SYCE1 PF15233.6 RLN89720.1 - 0.34 11.0 39.0 0.13 12.3 19.4 2.9 1 1 1 3 3 3 0 Synaptonemal complex central element protein 1 AHSP PF09236.10 RLN89720.1 - 0.55 10.7 6.5 6.2 7.3 1.5 2.9 1 1 1 2 2 2 0 Alpha-haemoglobin stabilising protein Cytomega_UL84 PF06284.11 RLN89721.1 - 0.0023 16.5 5.8 0.0035 15.9 5.8 1.1 1 0 0 1 1 1 1 Cytomegalovirus UL84 protein DnaJ_C PF01556.18 RLN89722.1 - 6.7e-43 146.3 0.0 1.1e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RLN89722.1 - 9.6e-27 92.9 1.3 1.8e-26 92.1 1.3 1.5 1 0 0 1 1 1 1 DnaJ domain p450 PF00067.22 RLN89723.1 - 1.3e-41 142.9 0.0 1.6e-41 142.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 2OG-FeII_Oxy_2 PF13532.6 RLN89724.1 - 6.8e-39 134.1 0.0 8.6e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_trans_1_4 PF13692.6 RLN89724.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 PIG-H PF10181.9 RLN89725.1 - 1.3e-09 37.8 0.1 2e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component CPSF_A PF03178.15 RLN89726.1 - 3.1e-79 266.6 0.0 3.8e-79 266.3 0.0 1.0 1 0 0 1 1 1 1 CPSF A subunit region Myosin_head PF00063.21 RLN89727.1 - 2.6e-196 653.9 0.0 5.4e-196 652.8 0.0 1.4 2 0 0 2 2 2 1 Myosin head (motor domain) AAA_22 PF13401.6 RLN89727.1 - 0.0054 17.0 0.0 0.028 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN89727.1 - 0.0081 16.6 0.0 0.025 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 RLN89727.1 - 0.046 13.0 0.0 0.09 12.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 RLN89727.1 - 0.08 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_membrane PF00664.23 RLN89728.1 - 2.8e-46 158.4 30.7 7.8e-26 91.3 14.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN89728.1 - 5.5e-22 78.7 0.0 3.3e-21 76.2 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 RLN89728.1 - 0.0015 19.0 0.0 0.0041 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 RLN89728.1 - 0.04 13.2 0.1 0.075 12.3 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 RLN89728.1 - 0.042 13.8 0.1 0.077 12.9 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 RLN89728.1 - 0.054 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.19 RLN89728.1 - 0.079 12.4 0.1 13 5.1 0.1 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain bZIP_1 PF00170.21 RLN89729.1 - 0.0019 18.3 6.4 0.0019 18.3 6.4 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 RLN89729.1 - 0.11 12.6 9.4 0.068 13.3 6.5 2.1 2 0 0 2 2 2 0 Basic region leucine zipper CCDC23 PF15674.5 RLN89729.1 - 0.38 10.8 4.1 0.84 9.7 4.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 23 Actin PF00022.19 RLN89730.1 - 5.4e-143 476.5 0.0 1.8e-142 474.8 0.0 1.7 1 1 0 1 1 1 1 Actin MatE PF01554.18 RLN89731.1 - 1.9e-60 203.2 25.8 1.1e-31 109.7 5.9 3.0 2 1 1 3 3 3 2 MatE Polysacc_synt_C PF14667.6 RLN89731.1 - 0.00022 21.3 10.9 0.00022 21.3 10.9 3.7 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 RLN89732.1 - 5.4e-55 185.4 32.1 1.2e-31 109.6 13.1 2.9 3 0 0 3 3 3 2 MatE bZIP_1 PF00170.21 RLN89733.1 - 0.015 15.4 11.4 0.018 15.1 6.8 2.5 2 0 0 2 2 2 0 bZIP transcription factor CCDC23 PF15674.5 RLN89733.1 - 0.11 12.5 5.8 0.28 11.2 5.8 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 23 bZIP_2 PF07716.15 RLN89733.1 - 0.31 11.1 19.3 0.089 12.9 9.1 2.7 3 0 0 3 3 3 0 Basic region leucine zipper Peptidase_C50 PF03568.17 RLN89734.1 - 1.1e-05 24.8 0.0 3.1e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.6 RLN89734.1 - 0.00045 20.4 2.6 0.16 12.2 0.5 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN89734.1 - 0.016 15.3 0.2 0.76 10.0 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3741 PF12552.8 RLN89734.1 - 0.18 11.8 0.9 3.5 7.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3741) Cpn60_TCP1 PF00118.24 RLN89735.1 - 3.1e-17 62.4 0.1 3.5e-17 62.2 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA_lid_6 PF17866.1 RLN89737.1 - 0.15 12.3 0.9 2.8 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA lid domain Flavodoxin_2 PF02525.17 RLN89738.1 - 1.1e-30 106.8 0.5 3e-27 95.6 0.0 2.0 2 0 0 2 2 2 2 Flavodoxin-like fold FMN_red PF03358.15 RLN89738.1 - 2.9e-11 43.3 0.0 6.9e-11 42.1 0.0 1.5 1 1 0 1 1 1 1 NADPH-dependent FMN reductase PriCT_2 PF08707.11 RLN89738.1 - 0.1 13.0 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) 4HBT PF03061.22 RLN89738.1 - 0.17 12.3 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase superfamily DNA_pol_A_exo1 PF01612.20 RLN89739.1 - 2.2e-21 76.3 0.0 3.4e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease zf-C2H2_4 PF13894.6 RLN89739.1 - 1.5 9.8 8.8 1.1 10.2 1.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger W2 PF02020.18 RLN89740.1 - 7.6e-14 51.6 8.3 7.6e-14 51.6 8.3 2.6 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 RLN89740.1 - 1.2e-05 24.8 13.6 0.23 11.3 0.7 4.2 1 1 4 5 5 5 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 RLN89740.1 - 0.0079 14.4 1.1 0.025 12.7 1.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 RLN89740.1 - 0.0092 15.7 9.7 1.1 9.0 0.4 3.6 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Promethin PF16015.5 RLN89741.1 - 0.06 13.3 0.7 0.11 12.4 0.2 1.6 2 0 0 2 2 2 0 Promethin Coq4 PF05019.13 RLN89743.1 - 3.8e-84 281.5 0.0 1.5e-83 279.5 0.0 1.8 1 1 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Phage_integrase PF00589.22 RLN89745.1 - 0.017 14.9 0.0 0.12 12.1 0.0 2.3 1 1 0 1 1 1 0 Phage integrase family gag_pre-integrs PF13976.6 RLN89747.1 - 0.0023 17.8 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain Zn_ribbon_SprT PF17283.2 RLN89748.1 - 0.032 14.2 3.0 0.21 11.5 1.1 2.5 1 1 1 2 2 2 0 SprT-like zinc ribbon domain FYVE PF01363.21 RLN89748.1 - 0.49 10.6 11.1 1.4 9.1 11.1 1.8 1 1 0 1 1 1 0 FYVE zinc finger Tnp_zf-ribbon_2 PF13842.6 RLN89748.1 - 8.9 7.2 11.2 0.15 12.8 3.7 2.0 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Carb_anhydrase PF00194.21 RLN89749.1 - 1.5e-30 106.6 0.0 2.7e-22 79.5 0.0 2.4 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase LRR_6 PF13516.6 RLN89753.1 - 1.8e-08 33.8 0.3 0.23 11.6 0.0 5.7 6 0 0 6 6 6 4 Leucine Rich repeat DHC_N2 PF08393.13 RLN89754.1 - 1.1e-53 182.7 0.0 1.1e-53 182.7 0.0 3.9 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 RLN89754.1 - 9.4e-17 61.1 0.0 3.8e-08 33.0 0.0 4.5 4 0 0 4 4 4 3 P-loop containing dynein motor region MT PF12777.7 RLN89754.1 - 1.4e-14 53.9 0.4 2.9e-14 52.9 0.4 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_6 PF12774.7 RLN89754.1 - 1.5e-06 27.4 0.0 0.0022 17.0 0.0 2.5 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 RLN89754.1 - 1.7e-05 24.8 0.1 0.17 11.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 RLN89754.1 - 0.0047 17.5 0.1 0.22 12.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 RLN89754.1 - 0.032 14.2 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 RLN89754.1 - 0.032 14.5 0.1 0.5 10.6 0.0 3.2 2 0 0 2 2 2 0 AAA domain AAA_8 PF12780.7 RLN89754.1 - 0.042 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 DUF5631 PF18645.1 RLN89754.1 - 0.057 13.8 2.2 1.2 9.5 0.3 3.7 3 0 0 3 3 2 0 Family of unknown function (DUF5631) TsaE PF02367.17 RLN89754.1 - 0.074 13.1 0.7 0.86 9.6 0.0 2.8 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 RLN89754.1 - 0.079 12.9 0.0 0.38 10.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 RLN89754.1 - 0.098 12.4 0.2 14 5.5 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 RLN89754.1 - 0.098 13.2 0.2 1.4 9.4 0.0 3.2 2 0 0 2 2 2 0 ABC transporter AAA_lid_1 PF17857.1 RLN89754.1 - 0.099 12.9 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA+ lid domain AAA PF00004.29 RLN89754.1 - 0.1 13.0 0.0 0.5 10.8 0.0 2.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 RLN89754.1 - 0.19 11.9 0.0 0.19 11.9 0.0 3.3 4 0 0 4 4 2 0 AAA domain ING PF12998.7 RLN89754.1 - 1 10.0 8.2 0.073 13.7 0.6 3.1 3 0 0 3 3 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF4203 PF13886.6 RLN89755.1 - 1e-06 28.5 0.2 1.1e-06 28.5 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) LSM14 PF12701.7 RLN89756.1 - 1.2e-26 92.6 0.0 2.1e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 RLN89756.1 - 4.6e-06 27.4 0.1 4.6e-06 27.4 0.1 2.6 2 1 1 3 3 3 1 FDF domain SM-ATX PF14438.6 RLN89756.1 - 0.011 15.8 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain TFIIA PF03153.13 RLN89756.1 - 1.1 9.1 14.7 1.4 8.9 14.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF601 PF04642.12 RLN89756.1 - 3.6 7.0 5.1 6.8 6.1 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF601 zf-RING_2 PF13639.6 RLN89757.1 - 5.1e-08 33.1 14.2 8.7e-08 32.4 14.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RLN89757.1 - 1.6e-06 27.8 14.5 2.9e-06 27.1 14.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN89757.1 - 2.5e-06 27.3 12.2 4e-06 26.6 12.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN89757.1 - 4.1e-06 26.5 15.4 4.1e-06 26.5 15.4 2.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN89757.1 - 6.7e-05 22.8 10.4 6.7e-05 22.8 10.4 1.8 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 RLN89757.1 - 0.00025 21.1 11.3 0.00061 19.9 11.1 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 RLN89757.1 - 0.0004 20.3 13.2 0.00066 19.6 13.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 RLN89757.1 - 0.0036 17.4 8.5 0.0062 16.6 8.5 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 RLN89757.1 - 0.0078 16.5 14.8 0.03 14.6 14.8 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 RLN89757.1 - 0.013 15.3 13.6 0.024 14.5 13.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 U-box PF04564.15 RLN89757.1 - 0.061 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 U-box domain Rx_N PF18052.1 RLN89757.1 - 0.18 12.1 2.5 0.19 12.0 0.2 2.2 2 1 0 2 2 2 0 Rx N-terminal domain Baculo_IE-1 PF05290.11 RLN89757.1 - 4.6 7.2 7.1 9.2 6.2 7.1 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 RLN89757.1 - 7.1 6.5 11.4 17 5.3 11.4 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain fn3 PF00041.21 RLN89762.1 - 0.003 17.8 1.9 0.012 16.0 0.1 2.4 2 0 0 2 2 2 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RLN89762.1 - 0.028 15.0 0.8 0.82 10.3 0.0 2.5 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Filament PF00038.21 RLN89762.1 - 3 7.3 45.7 0.3 10.6 36.6 2.1 1 1 1 2 2 2 0 Intermediate filament protein RRN3 PF05327.11 RLN89763.1 - 3.1e-96 323.2 0.3 3.1e-96 323.2 0.3 3.2 2 1 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 MutS_V PF00488.21 RLN89764.1 - 5.9e-68 228.6 0.1 9.9e-68 227.9 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 RLN89764.1 - 1.7e-18 67.5 3.8 4.7e-18 66.1 2.7 2.1 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 RLN89764.1 - 7e-15 55.5 0.0 1.7e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 RLN89764.1 - 2.6e-10 40.5 1.2 5.3e-10 39.5 0.1 2.2 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.20 RLN89764.1 - 0.12 12.6 0.1 0.39 11.0 0.0 2.0 2 0 0 2 2 2 0 MutS domain I Fascin PF06268.13 RLN89765.1 - 0.004 17.4 0.2 0.0072 16.5 0.2 1.5 1 1 0 1 1 1 1 Fascin domain TPR_1 PF00515.28 RLN89770.1 - 1.9e-19 68.6 6.6 5.7e-06 25.9 0.1 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 RLN89770.1 - 1.9e-16 58.8 5.0 9.1e-05 22.4 0.1 5.4 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 RLN89770.1 - 7.6e-16 56.9 17.9 2.2e-05 24.2 0.6 5.8 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 RLN89770.1 - 1.6e-14 53.3 22.3 0.00051 20.6 1.2 6.0 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 RLN89770.1 - 6.1e-14 52.4 20.3 1.8e-05 25.3 3.9 4.3 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN89770.1 - 6.5e-14 51.3 5.6 0.0022 17.6 0.0 5.0 3 1 2 5 5 5 4 TPR repeat TPR_12 PF13424.6 RLN89770.1 - 1.4e-12 47.8 24.2 5e-08 33.1 3.5 4.1 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 RLN89770.1 - 2e-09 37.2 0.8 2.1 8.9 0.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 RLN89770.1 - 5.6e-09 36.1 9.0 0.039 14.6 0.0 5.1 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 RLN89770.1 - 1.8e-08 34.8 11.6 6.6e-05 23.3 0.8 3.9 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN89770.1 - 2.7e-08 33.3 10.0 0.026 14.5 0.2 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN89770.1 - 0.0004 20.5 14.5 0.092 12.9 1.3 4.1 4 1 1 5 5 5 2 Tetratricopeptide repeat DUF3856 PF12968.7 RLN89770.1 - 0.0013 18.8 5.7 0.29 11.2 2.0 3.4 1 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 RLN89770.1 - 0.0014 18.4 15.0 0.95 9.4 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN89770.1 - 0.0021 18.3 6.1 0.028 14.6 0.2 3.1 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 RLN89770.1 - 0.0071 15.6 11.8 0.13 11.5 0.8 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 RLN89770.1 - 0.016 15.8 20.6 0.091 13.4 1.2 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat PPR PF01535.20 RLN89770.1 - 0.1 12.9 0.0 23 5.5 0.0 3.1 2 0 0 2 2 2 0 PPR repeat Methyltransf_32 PF13679.6 RLN89771.1 - 0.052 13.5 0.4 0.15 12.1 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain FA_desaturase PF00487.24 RLN89771.1 - 0.073 12.9 0.4 0.13 12.1 0.4 1.3 1 0 0 1 1 1 0 Fatty acid desaturase DUF4191 PF13829.6 RLN89771.1 - 0.2 11.0 0.2 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Tetraspanin PF00335.20 RLN89772.1 - 7.7e-10 38.9 8.7 1.9e-09 37.6 8.9 1.6 1 1 1 2 2 2 1 Tetraspanin family DUF4064 PF13273.6 RLN89772.1 - 0.012 15.9 7.6 0.012 15.9 7.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF2385 PF09539.10 RLN89772.1 - 0.026 15.1 0.5 0.058 13.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) DUF2207 PF09972.9 RLN89772.1 - 0.026 13.3 3.4 0.15 10.8 2.5 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF5373 PF17343.2 RLN89772.1 - 0.097 12.5 0.2 0.22 11.4 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5373) DUF202 PF02656.15 RLN89772.1 - 0.47 10.9 10.6 0.31 11.5 2.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Tetraspanin PF00335.20 RLN89773.1 - 3.3e-18 66.2 8.1 4.6e-18 65.8 8.1 1.2 1 0 0 1 1 1 1 Tetraspanin family Cytomega_TRL10 PF06084.11 RLN89773.1 - 0.00096 19.2 0.1 0.00096 19.2 0.1 2.3 2 0 0 2 2 2 1 Cytomegalovirus TRL10 protein Pex24p PF06398.11 RLN89773.1 - 0.0065 15.5 0.0 0.012 14.6 0.0 1.5 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin EphA2_TM PF14575.6 RLN89773.1 - 0.22 12.4 4.4 6.1 7.8 0.0 3.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain SLATT_3 PF18184.1 RLN89773.1 - 0.27 11.4 0.4 0.54 10.4 0.4 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 Reprolysin_2 PF13574.6 RLN89773.1 - 0.4 10.5 1.6 6.1 6.7 0.1 2.2 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Comm PF15957.5 RLN89773.1 - 0.46 10.8 4.0 6.9 7.0 0.1 3.1 2 1 1 3 3 3 0 Commissureless FA_desaturase PF00487.24 RLN89773.1 - 2.6 7.8 6.4 1.3 8.8 4.2 1.6 2 0 0 2 2 2 0 Fatty acid desaturase RCR PF12273.8 RLN89773.1 - 7.3 7.3 7.0 2.5 8.8 0.1 2.4 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Tetraspanin PF00335.20 RLN89774.1 - 3e-14 53.3 10.8 3.8e-14 53.0 10.8 1.1 1 0 0 1 1 1 1 Tetraspanin family Herpes_UL49_5 PF05702.11 RLN89774.1 - 0.035 14.2 0.7 0.035 14.2 0.7 2.0 2 0 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein Comm PF15957.5 RLN89774.1 - 0.19 12.0 0.2 0.19 12.0 0.2 2.7 3 0 0 3 3 3 0 Commissureless DUF4500 PF14937.6 RLN89774.1 - 0.33 11.0 1.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) Sigma_reg_N PF13800.6 RLN89774.1 - 1.3 9.3 3.3 12 6.3 0.0 3.2 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Tub PF01167.18 RLN89775.1 - 8.4e-91 304.0 0.0 1.1e-90 303.6 0.0 1.2 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 RLN89775.1 - 0.062 12.9 0.0 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) DUF3224 PF11528.8 RLN89776.1 - 0.13 12.1 2.3 19 5.1 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3224) Tetraspanin PF00335.20 RLN89777.1 - 2.2e-06 27.5 2.3 4.8e-06 26.4 2.3 1.5 1 1 0 1 1 1 1 Tetraspanin family IgG_binding_B PF01378.17 RLN89777.1 - 0.099 12.7 0.5 0.25 11.4 0.5 1.7 1 0 0 1 1 1 0 B domain Wzy_C PF04932.15 RLN89777.1 - 1 9.0 3.4 1.1 8.9 0.1 2.4 3 0 0 3 3 3 0 O-Antigen ligase DUF4131 PF13567.6 RLN89777.1 - 7.6 6.2 10.3 0.19 11.3 1.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Tetraspanin PF00335.20 RLN89778.1 - 1.6e-17 64.0 8.8 2.5e-17 63.4 8.8 1.3 1 1 0 1 1 1 1 Tetraspanin family Pex24p PF06398.11 RLN89778.1 - 0.0011 18.0 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin UPF0239 PF06783.11 RLN89778.1 - 0.045 13.9 0.9 3.4 7.9 0.0 2.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0239) TMEM154 PF15102.6 RLN89778.1 - 0.056 13.3 0.0 6.3 6.7 0.0 2.4 2 0 0 2 2 2 0 TMEM154 protein family LPD1 PF18796.1 RLN89778.1 - 0.091 12.9 0.1 0.94 9.6 0.0 2.4 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 1 Comm PF15957.5 RLN89778.1 - 0.49 10.7 3.0 3.5 8.0 0.1 2.9 2 1 1 3 3 3 0 Commissureless TMEM100 PF16311.5 RLN89778.1 - 0.63 9.6 0.0 0.63 9.6 0.0 2.1 2 1 0 2 2 2 0 Transmembrane protein 100 EphA2_TM PF14575.6 RLN89778.1 - 1.2 10.1 11.0 4.5 8.2 0.0 3.5 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Cytomega_TRL10 PF06084.11 RLN89778.1 - 7.1 6.6 9.7 0.38 10.8 0.1 2.5 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein PBP_N PF17093.5 RLN89779.1 - 0.73 10.1 0.0 0.73 10.1 0.0 2.8 3 0 0 3 3 3 0 Penicillin-binding protein N-terminus Peptidase_C2 PF00648.21 RLN89780.1 - 2.5e-11 43.1 0.1 1.2e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 Calpain family cysteine protease DZR PF12773.7 RLN89781.1 - 0.0043 17.0 2.1 0.0043 17.0 2.1 2.6 1 1 1 2 2 2 2 Double zinc ribbon Mu-like_Com PF10122.9 RLN89781.1 - 0.071 12.6 6.9 5.4 6.5 0.5 3.7 3 0 0 3 3 3 0 Mu-like prophage protein Com Zn-ribbon_8 PF09723.10 RLN89781.1 - 8.1 6.7 10.7 1.2 9.3 0.5 3.5 4 0 0 4 4 4 0 Zinc ribbon domain CTD_bind PF04818.13 RLN89782.1 - 1.8e-07 31.8 0.0 8.7e-07 29.7 0.0 2.3 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CWC25 PF12542.8 RLN89785.1 - 4.1e-18 66.2 0.2 4.1e-18 66.2 0.2 3.2 2 1 1 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 RLN89785.1 - 1.3e-14 54.1 11.4 1.3e-14 54.1 11.4 3.8 3 2 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF755 PF05501.11 RLN89785.1 - 2.6 8.3 25.0 0.24 11.7 18.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF4080 PF13311.6 RLN89785.1 - 2.9 8.0 8.7 0.14 12.3 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4080) DUF2407_C PF13373.6 RLN89785.1 - 5.4 7.2 7.8 0.79 9.9 0.8 2.2 2 0 0 2 2 2 0 DUF2407 C-terminal domain Rubis-subs-bind PF09273.11 RLN89786.1 - 4.7e-15 56.4 10.9 2.2e-11 44.5 0.4 4.8 3 0 0 3 3 3 2 Rubisco LSMT substrate-binding SET PF00856.28 RLN89786.1 - 0.057 13.8 0.0 0.057 13.8 0.0 7.3 6 2 1 7 7 7 0 SET domain SET PF00856.28 RLN89787.1 - 1.6e-11 44.9 0.1 1.4e-09 38.6 0.0 2.2 1 1 1 2 2 2 2 SET domain SAF PF08666.12 RLN89787.1 - 0.059 14.0 0.0 0.65 10.7 0.0 2.2 1 1 0 1 1 1 0 SAF domain Dor1 PF04124.12 RLN89788.1 - 1.6e-31 109.2 2.7 4e-28 98.1 1.8 2.5 1 1 0 2 2 2 2 Dor1-like family Vps51 PF08700.11 RLN89788.1 - 2.3e-05 24.4 2.9 5.7e-05 23.1 0.3 2.7 2 1 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.6 RLN89788.1 - 0.043 13.6 0.1 0.086 12.6 0.1 1.5 1 1 0 1 1 1 0 Exocyst complex component Sec5 Lactamase_B_2 PF12706.7 RLN89789.1 - 5.3e-14 52.2 0.0 1.3e-13 50.9 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain SmaI PF17411.2 RLN89789.1 - 0.19 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Type II site-specific deoxyribonuclease Lactamase_B_2 PF12706.7 RLN89790.1 - 8.1e-25 87.5 0.0 2.3e-24 86.0 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 RLN89790.1 - 3e-06 27.4 0.6 6e-06 26.4 0.6 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily SmaI PF17411.2 RLN89790.1 - 0.058 12.6 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Type II site-specific deoxyribonuclease HSP70 PF00012.20 RLN89791.1 - 1e-14 53.7 0.1 1.1e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein DbpA PF03880.15 RLN89791.1 - 0.074 13.1 0.0 0.093 12.7 0.0 1.1 1 0 0 1 1 1 0 DbpA RNA binding domain FtsA PF14450.6 RLN89791.1 - 0.11 12.9 0.1 0.15 12.4 0.1 1.2 1 0 0 1 1 1 0 Cell division protein FtsA Acyl_transf_1 PF00698.21 RLN89792.1 - 1.8e-52 178.8 0.0 2.5e-51 175.1 0.0 2.3 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.19 RLN89792.1 - 3.4e-18 65.4 0.0 8.1e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain AAA_18 PF13238.6 RLN89796.1 - 0.00013 22.5 0.2 0.00036 21.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 RLN89796.1 - 0.14 12.3 0.1 0.7 10.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain RRM_1 PF00076.22 RLN89797.1 - 1.2e-16 60.3 0.1 5.2e-16 58.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN89797.1 - 0.00057 20.0 0.1 0.0024 17.9 0.0 2.0 2 1 0 2 2 2 1 RNA recognition motif RRM_3 PF08777.11 RLN89797.1 - 0.018 15.1 0.1 0.063 13.3 0.1 1.9 1 0 0 1 1 1 0 RNA binding motif Cut8 PF08559.10 RLN89797.1 - 0.04 13.5 0.6 0.063 12.9 0.4 1.4 1 1 1 2 2 2 0 Cut8, nuclear proteasome tether protein LRR_4 PF12799.7 RLN89798.1 - 1e-17 63.9 29.3 1.8e-06 28.2 1.7 5.6 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN89798.1 - 2e-11 43.7 12.7 1.4e-10 41.0 0.4 3.8 2 1 2 4 4 4 3 Leucine-rich repeat LRR_8 PF13855.6 RLN89798.1 - 2.6e-10 39.9 35.0 0.00065 19.4 6.6 5.5 4 1 1 5 5 5 4 Leucine rich repeat RRM_1 PF00076.22 RLN89801.1 - 1.2e-14 53.9 0.0 1.5e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN89801.1 - 0.00068 19.7 0.0 0.0013 18.9 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif PHM7_cyt PF14703.6 RLN89801.1 - 0.22 11.7 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Endonuclease_NS PF01223.23 RLN89802.1 - 2.5e-54 184.5 0.0 3.1e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease TRP PF06011.12 RLN89803.1 - 1.6e-35 122.6 16.4 2e-35 122.3 16.4 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel Chloroplast_duf PF14476.6 RLN89803.1 - 0.36 9.7 3.2 0.51 9.3 1.7 1.9 2 0 0 2 2 2 0 Petal formation-expressed DUF2431 PF10354.9 RLN89805.1 - 7.5e-37 127.2 0.0 1.1e-36 126.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) FDX-ACB PF03147.14 RLN89805.1 - 3.1e-08 33.9 0.0 6.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain DUF3464 PF11947.8 RLN89806.1 - 0.0015 18.3 0.6 0.0024 17.6 0.6 1.3 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 Kei1 PF08552.11 RLN89806.1 - 0.12 12.2 2.7 0.13 12.2 2.3 1.3 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF5308 PF17233.2 RLN89806.1 - 0.19 11.9 6.2 0.11 12.8 4.1 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5308) DUF5601 PF18151.1 RLN89807.1 - 2.2e-07 31.1 0.0 5.6e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) Glyco_transf_41 PF13844.6 RLN89808.1 - 2.9e-75 253.5 0.5 3.8e-41 141.0 0.0 2.4 1 1 1 2 2 2 2 Glycosyl transferase family 41 Methyltransf_11 PF08241.12 RLN89808.1 - 1e-09 38.9 0.0 3.1e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain TPR_1 PF00515.28 RLN89808.1 - 3.4e-08 33.0 0.0 0.00013 21.6 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN89808.1 - 1.6e-07 31.7 0.0 3.8e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN89808.1 - 1.8e-06 28.5 0.3 6.3e-06 26.7 0.0 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN89808.1 - 6.2e-06 25.8 0.0 1.2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 RLN89808.1 - 6.2e-05 22.8 0.0 0.02 14.9 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN89808.1 - 6.4e-05 22.9 0.0 0.00066 19.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Methyltransf_25 PF13649.6 RLN89808.1 - 0.00015 22.4 0.1 0.0006 20.5 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain TPR_14 PF13428.6 RLN89808.1 - 0.00026 21.6 0.0 0.00098 19.7 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat Methyltransf_12 PF08242.12 RLN89808.1 - 0.0015 19.2 0.0 0.0044 17.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain TPR_17 PF13431.6 RLN89808.1 - 0.012 15.9 0.1 0.085 13.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN89808.1 - 0.016 15.5 0.4 0.14 12.5 0.1 2.5 2 1 0 2 2 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN89808.1 - 0.019 15.6 0.0 0.91 10.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN89808.1 - 0.023 14.9 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Methyltransf_23 PF13489.6 RLN89808.1 - 0.029 14.2 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TPR_7 PF13176.6 RLN89808.1 - 0.08 13.0 0.0 0.33 11.1 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Carn_acyltransf PF00755.20 RLN89809.1 - 1.5e-178 595.1 0.0 1.7e-178 594.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase HTH_15 PF12324.8 RLN89811.1 - 0.0072 16.2 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of alkylmercury lyase Kinesin PF00225.23 RLN89812.1 - 2.7e-59 200.8 0.1 1e-28 100.2 0.1 2.8 2 1 1 3 3 3 2 Kinesin motor domain Mago-bind PF09282.10 RLN89812.1 - 0.00033 20.5 0.5 0.00079 19.2 0.5 1.6 1 0 0 1 1 1 1 Mago binding Microtub_bd PF16796.5 RLN89812.1 - 0.0011 18.9 0.0 0.05 13.5 0.0 2.2 1 1 1 2 2 2 1 Microtubule binding Formyl_trans_C PF02911.18 RLN89814.1 - 3.3e-12 46.5 0.0 4.9e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Transgly_assoc PF04226.13 RLN89815.1 - 0.034 14.4 0.8 0.082 13.2 0.8 1.6 1 0 0 1 1 1 0 Transglycosylase associated protein PsbX PF06596.11 RLN89815.1 - 0.04 13.9 1.9 0.093 12.8 1.9 1.7 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) DUF1180 PF06679.12 RLN89815.1 - 0.46 10.9 4.3 0.82 10.1 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PT PF04886.12 RLN89816.1 - 1.7e-06 27.4 58.2 1.8e-05 24.2 26.0 4.5 1 1 2 3 3 3 2 PT repeat Thaumatin PF00314.17 RLN89816.1 - 0.0013 18.4 3.4 1.4 8.5 0.8 3.6 2 1 1 3 3 3 3 Thaumatin family DUF2370 PF10176.9 RLN89816.1 - 0.068 12.8 0.5 0.11 12.1 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) MHYT PF03707.16 RLN89817.1 - 1 9.6 5.0 0.42 10.8 0.7 2.4 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat PIP5K PF01504.18 RLN89818.1 - 4.9e-63 212.9 0.0 7.9e-63 212.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Na_H_Exchanger PF00999.21 RLN89818.1 - 1.3e-07 30.8 8.1 1.3e-07 30.8 8.1 2.0 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family 7tm_2 PF00002.24 RLN89818.1 - 7.9e-05 22.1 4.7 7.9e-05 22.1 4.7 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) DUF2721 PF11026.8 RLN89818.1 - 0.0075 16.2 0.1 0.0075 16.2 0.1 3.7 3 2 1 4 4 4 1 Protein of unknown function (DUF2721) 7tm_1 PF00001.21 RLN89818.1 - 0.031 13.6 10.2 0.072 12.4 10.2 1.6 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Frizzled PF01534.17 RLN89818.1 - 1.1 8.2 10.1 0.029 13.4 2.5 2.1 2 1 0 2 2 2 0 Frizzled/Smoothened family membrane region AMP_N PF05195.16 RLN89820.1 - 2.1e-25 88.8 0.0 2.4e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Ribosomal_S8e PF01201.22 RLN89821.1 - 7.5e-50 168.7 6.2 1.2e-47 161.5 6.2 2.1 1 1 0 1 1 1 1 Ribosomal protein S8e CDPS PF16715.5 RLN89821.1 - 1.6 8.3 5.2 2.5 7.7 4.7 1.5 2 0 0 2 2 2 0 Cyclodipeptide synthase Peptidase_M24 PF00557.24 RLN89822.1 - 8.9e-47 159.5 0.0 1.1e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 RLN89822.1 - 9.3e-09 35.1 0.0 1.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Thiolase_N PF00108.23 RLN89823.1 - 8.2e-70 235.1 0.1 2.2e-69 233.7 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RLN89823.1 - 1e-34 118.8 0.0 2.9e-34 117.3 0.0 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain SpoVAD PF07451.11 RLN89823.1 - 1.4e-06 27.3 0.1 6e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.26 RLN89823.1 - 0.00048 19.8 2.1 0.00048 19.8 2.1 2.5 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain C-C_Bond_Lyase PF15617.6 RLN89823.1 - 0.03 13.5 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold ACP_syn_III PF08545.10 RLN89823.1 - 0.046 13.6 0.5 2 8.3 0.2 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FYVE PF01363.21 RLN89824.1 - 0.0077 16.3 8.5 0.014 15.5 8.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger Bd3614-deam PF14439.6 RLN89824.1 - 0.11 12.5 0.2 0.21 11.6 0.2 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase FYVE_2 PF02318.16 RLN89824.1 - 0.2 11.9 3.8 0.5 10.6 3.8 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger Pkinase_Tyr PF07714.17 RLN89827.1 - 2.1e-25 89.5 0.0 1.7e-24 86.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN89827.1 - 7.7e-22 77.9 0.0 1.1e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CD34_antigen PF06365.12 RLN89827.1 - 2e-05 24.3 0.1 3.4e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family Herpes_gE PF02480.16 RLN89827.1 - 0.0016 17.3 0.1 0.0024 16.7 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM51 PF15345.6 RLN89827.1 - 0.0096 15.8 0.5 0.016 15.1 0.5 1.4 1 1 0 1 1 1 1 Transmembrane protein 51 TMEM154 PF15102.6 RLN89827.1 - 0.01 15.8 0.0 0.073 13.0 0.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family LST1 PF05083.13 RLN89827.1 - 0.087 13.1 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 LST-1 protein DUF2207 PF09972.9 RLN89827.1 - 0.094 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Shisa PF13908.6 RLN89827.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator UPF0560 PF10577.9 RLN89827.1 - 0.12 10.8 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 EphA2_TM PF14575.6 RLN89827.1 - 0.14 13.1 0.0 0.25 12.3 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rhabdo_glycop PF00974.18 RLN89827.1 - 0.16 10.4 0.0 0.24 9.8 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Ni_hydr_CYTB PF01292.20 RLN89828.1 - 0.14 11.8 15.1 0.29 10.7 1.9 2.3 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 tRNA-synt_1 PF00133.22 RLN89829.1 - 3.2e-58 197.4 0.1 4.8e-40 137.4 2.6 6.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 RLN89829.1 - 6.3e-53 179.0 0.0 9.1e-53 178.5 0.0 1.2 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 RLN89829.1 - 3.1e-25 88.8 0.0 2.9e-19 69.1 0.0 4.1 3 1 1 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 RLN89829.1 - 7.7e-13 48.7 0.0 1.3e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 RLN89829.1 - 0.13 11.6 0.0 4 6.7 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Lar_restr_allev PF14354.6 RLN89829.1 - 0.25 11.7 1.0 2.2 8.7 0.7 2.4 2 0 0 2 2 2 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.10 RLN89829.1 - 0.34 11.1 3.0 2.4 8.3 0.4 2.7 2 0 0 2 2 2 0 Zinc ribbon domain DNA_ligase_ZBD PF03119.16 RLN89829.1 - 0.89 9.6 7.2 1.2 9.2 0.0 2.7 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Glyco_hydro_28 PF00295.17 RLN89830.1 - 2.1e-74 250.5 18.0 2.1e-74 250.5 18.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 DDE_Tnp_4 PF13359.6 RLN89834.1 - 2.7e-27 95.4 0.0 3.7e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 RLN89834.1 - 5.7e-06 26.1 0.0 9.2e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 RLN89834.1 - 0.00055 20.3 0.3 0.0011 19.3 0.3 1.4 1 0 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 RLN89834.1 - 0.00056 19.6 0.0 0.00078 19.1 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DUF3135 PF11333.8 RLN89834.1 - 0.14 12.4 0.1 0.36 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) AA_kinase PF00696.28 RLN89835.1 - 4.4e-36 124.7 0.0 1.4e-35 123.0 0.0 1.8 1 1 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 RLN89835.1 - 0.18 11.6 0.1 1.3 8.9 0.1 2.3 2 0 0 2 2 2 0 ACT domain Sel1 PF08238.12 RLN89836.1 - 1.7e-42 142.9 28.7 2.7e-07 31.0 1.5 7.2 7 0 0 7 7 7 7 Sel1 repeat TPR_7 PF13176.6 RLN89836.1 - 0.26 11.4 9.4 2.9 8.1 0.3 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat RWP-RK PF02042.15 RLN89837.1 - 1.2e-19 70.0 0.3 3.7e-19 68.4 0.2 1.9 2 0 0 2 2 2 1 RWP-RK domain Abhydrolase_4 PF08386.10 RLN89838.1 - 3.5e-06 27.0 0.1 1.3e-05 25.2 0.1 2.0 1 0 0 1 1 1 1 TAP-like protein TMEM154 PF15102.6 RLN89838.1 - 0.00033 20.6 0.0 0.0022 17.9 0.0 2.5 1 0 0 1 1 1 1 TMEM154 protein family Nitrate_red_gam PF02665.14 RLN89838.1 - 0.031 13.8 0.2 0.073 12.6 0.2 1.5 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Hydrolase_4 PF12146.8 RLN89838.1 - 0.052 12.8 0.0 4.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Insulin_TMD PF17870.1 RLN89838.1 - 0.074 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment WD40 PF00400.32 RLN89839.1 - 5.6e-17 61.8 8.7 0.00016 22.4 0.5 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN89839.1 - 1.6e-05 25.1 0.0 0.18 12.1 0.0 2.9 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain AMPK1_CBM PF16561.5 RLN89839.1 - 0.094 12.9 1.1 0.22 11.7 0.2 2.0 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase Marek_SORF3 PF07153.11 RLN89839.1 - 0.12 11.7 0.0 0.33 10.3 0.0 1.6 1 1 1 2 2 2 0 Marek's disease-like virus SORF3 protein Uma2 PF05685.12 RLN89840.1 - 0.0016 18.0 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative restriction endonuclease HTH_Tnp_Tc5 PF03221.16 RLN89841.1 - 4.1e-10 39.5 0.2 1.2e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 RLN89841.1 - 8.5e-06 25.4 0.3 2.8e-05 23.7 0.1 1.9 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain HTH_32 PF13565.6 RLN89841.1 - 0.00059 20.4 0.3 0.0022 18.6 0.1 2.1 2 0 0 2 2 2 1 Homeodomain-like domain NYAP_N PF15439.6 RLN89841.1 - 0.057 12.6 0.6 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter HTH_Tnp_Tc5 PF03221.16 RLN89842.1 - 1.7e-05 24.8 0.0 3.9e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 RLN89842.1 - 0.022 14.5 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain HTH_33 PF13592.6 RLN89842.1 - 0.071 12.8 0.2 0.2 11.3 0.2 1.8 1 0 0 1 1 1 0 Winged helix-turn helix HTH_32 PF13565.6 RLN89842.1 - 1.6 9.4 0.0 1.6 9.4 0.0 2.8 4 0 0 4 4 4 0 Homeodomain-like domain Pyr_redox_2 PF07992.14 RLN89843.1 - 2e-55 188.1 0.9 3.3e-55 187.4 0.9 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 RLN89843.1 - 2e-29 102.1 0.1 4.8e-29 100.8 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 RLN89843.1 - 4e-12 46.0 0.0 1.4e-11 44.2 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RLN89843.1 - 1.7e-11 44.5 1.8 3.1e-09 37.3 0.2 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase zf-TAZ PF02135.16 RLN89843.1 - 1.7e-06 28.4 12.3 3.6e-06 27.4 12.3 1.5 1 0 0 1 1 1 1 TAZ zinc finger K_oxygenase PF13434.6 RLN89843.1 - 0.00027 20.2 0.0 0.00075 18.7 0.0 1.7 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 RLN89843.1 - 0.0012 18.1 1.0 0.0019 17.5 0.1 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 RLN89843.1 - 0.0029 16.8 2.1 0.0064 15.6 2.1 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 RLN89843.1 - 0.021 15.0 1.1 0.021 15.0 1.1 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 RLN89843.1 - 0.045 12.4 1.9 0.12 11.0 0.4 2.3 3 0 0 3 3 3 0 HI0933-like protein FAD_oxidored PF12831.7 RLN89843.1 - 0.053 12.9 0.2 0.09 12.1 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 RLN89843.1 - 0.15 11.6 5.0 0.095 12.3 2.3 2.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.22 RLN89843.1 - 4.7 6.2 5.0 0.47 9.5 0.6 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A PX PF00787.24 RLN89844.1 - 1.1e-05 25.3 0.1 3.2e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 PX domain Peptidase_S74 PF13884.6 RLN89845.1 - 8.1e-14 51.7 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Chaperone of endosialidase EGF_2 PF07974.13 RLN89845.1 - 9e-07 29.2 8.4 1.9e-06 28.1 8.4 1.5 1 0 0 1 1 1 1 EGF-like domain Bacillus_HBL PF05791.11 RLN89845.1 - 0.0014 18.5 0.2 0.0022 17.9 0.2 1.2 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) Laminin_EGF PF00053.24 RLN89845.1 - 0.043 14.0 9.5 0.11 12.7 9.5 1.6 1 0 0 1 1 1 0 Laminin EGF domain DHR10 PF18595.1 RLN89845.1 - 0.28 11.3 7.1 0.46 10.5 7.1 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Sec2p PF06428.11 RLN89845.1 - 1.4 8.9 5.0 2.8 8.0 5.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Sel1 PF08238.12 RLN89846.1 - 3.5e-37 126.0 26.0 8e-07 29.5 0.5 11.7 11 1 0 11 11 11 8 Sel1 repeat TPR_6 PF13174.6 RLN89846.1 - 0.042 14.5 10.4 23 5.9 0.7 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Kazal_2 PF07648.15 RLN89847.1 - 2.7e-16 59.4 27.2 5.1e-11 42.5 5.7 3.5 3 0 0 3 3 3 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 RLN89847.1 - 5.4e-12 45.5 16.1 1.9e-08 34.2 3.9 3.1 3 1 0 3 3 3 2 Kazal-type serine protease inhibitor domain ABC_tran PF00005.27 RLN89849.1 - 2.4e-50 170.6 0.0 3e-28 99.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 RLN89849.1 - 6e-47 160.6 23.2 2.1e-27 96.5 7.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 RLN89849.1 - 9.6e-11 41.5 6.2 0.0001 21.8 0.3 4.1 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RLN89849.1 - 7.4e-06 26.0 0.1 0.038 14.1 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 RLN89849.1 - 8.2e-05 23.1 0.0 0.056 13.8 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 RLN89849.1 - 0.00016 21.6 0.7 0.51 10.2 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase IstB_IS21 PF01695.17 RLN89849.1 - 0.0014 18.4 0.5 1.1 9.0 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_18 PF13238.6 RLN89849.1 - 0.0017 18.9 0.0 5.5 7.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 RLN89849.1 - 0.0018 18.6 0.8 1.4 9.2 0.1 2.8 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 RLN89849.1 - 0.0047 17.0 1.0 0.13 12.4 0.1 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_29 PF13555.6 RLN89849.1 - 0.0047 16.6 0.3 1.4 8.8 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 RLN89849.1 - 0.011 15.6 0.7 8.3 6.1 0.1 3.6 2 2 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RLN89849.1 - 0.018 15.6 0.1 1.7 9.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 RLN89849.1 - 0.032 13.4 0.3 4.2 6.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DEAD PF00270.29 RLN89849.1 - 0.048 13.4 0.6 0.18 11.5 0.1 2.1 2 1 0 2 2 2 0 DEAD/DEAH box helicase Zeta_toxin PF06414.12 RLN89849.1 - 0.087 12.1 0.2 1.7 7.9 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 RLN89849.1 - 0.088 13.0 0.4 5.6 7.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 RLN89849.1 - 0.13 11.2 0.3 7.1 5.5 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 RLN89849.1 - 0.18 11.3 0.2 21 4.6 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 RLN89849.1 - 0.31 10.7 3.0 12 5.6 0.1 3.2 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 RLN89849.1 - 0.45 10.6 5.1 4.7 7.2 0.4 2.6 3 0 0 3 3 2 0 Dynamin family NB-ARC PF00931.22 RLN89849.1 - 0.61 9.2 3.0 22 4.1 0.1 3.0 2 1 0 2 2 2 0 NB-ARC domain Sugar_tr PF00083.24 RLN89850.1 - 9.7e-99 331.2 18.1 1.1e-98 331.1 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN89850.1 - 1e-28 100.3 52.5 3.6e-24 85.4 32.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 RLN89850.1 - 0.1 11.0 13.2 0.62 8.4 5.6 2.4 2 1 0 2 2 2 0 Transmembrane secretion effector Ank_2 PF12796.7 RLN89851.1 - 5.4e-09 36.5 0.1 2.2e-07 31.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN89851.1 - 3.7e-08 33.7 1.0 0.0036 17.8 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN89851.1 - 0.00039 20.6 0.8 1 10.2 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeat Peptidase_C48 PF02902.19 RLN89852.1 - 2.7e-10 40.5 0.6 4.8e-10 39.6 0.6 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 RLN89852.1 - 0.07 11.8 0.1 0.45 9.2 0.0 1.9 1 1 1 2 2 2 0 Vaccinia virus I7 processing peptidase HAD_2 PF13419.6 RLN89855.1 - 1.3e-12 48.2 0.0 1.8e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RLN89855.1 - 8.1e-10 39.3 0.0 1e-09 39.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RLN89855.1 - 0.013 15.6 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like UCH PF00443.29 RLN89857.1 - 1.3e-41 142.8 0.1 3.5e-41 141.4 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN89857.1 - 2.6e-18 66.7 2.9 7.7e-18 65.1 0.6 3.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Utp13 PF08625.11 RLN89857.1 - 0.067 13.1 0.1 2.4 8.1 0.0 3.0 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain DUF5593 PF18007.1 RLN89857.1 - 1.6 9.4 3.7 15 6.4 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5593) Cys_rich_VLP PF14194.6 RLN89859.1 - 0.13 12.4 1.0 0.35 11.0 1.0 1.7 1 0 0 1 1 1 0 Cysteine-rich VLP Copine PF07002.16 RLN89860.1 - 3.5e-52 177.0 0.5 3.3e-51 173.8 0.0 2.3 2 0 0 2 2 2 1 Copine Ion_trans_2 PF07885.16 RLN89860.1 - 4.5e-31 106.6 24.3 9.8e-17 60.7 13.3 2.4 2 0 0 2 2 2 2 Ion channel C2 PF00168.30 RLN89860.1 - 1.6e-22 79.7 0.0 8.4e-13 48.5 0.0 2.5 2 0 0 2 2 2 2 C2 domain Ion_trans PF00520.31 RLN89860.1 - 1.4e-10 40.8 0.9 9.8e-05 21.7 0.1 2.3 2 0 0 2 2 2 2 Ion transport protein EF-hand_7 PF13499.6 RLN89860.1 - 3.2e-06 27.5 1.1 0.024 15.1 1.2 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN89860.1 - 1.3e-05 24.3 0.9 0.17 11.5 0.3 3.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN89860.1 - 1.9e-05 24.2 1.1 0.059 13.3 0.2 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 RLN89860.1 - 4.7e-05 22.7 7.9 0.04 13.4 0.8 3.4 3 1 0 3 3 3 2 EF hand UPF0669 PF17065.5 RLN89860.1 - 0.0047 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Putative cytokine, C6ORF120 EF-hand_8 PF13833.6 RLN89860.1 - 0.018 14.9 1.3 0.24 11.3 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair vWA-TerF-like PF10138.9 RLN89860.1 - 0.044 13.9 0.2 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 vWA found in TerF C terminus zf-C3HC4_2 PF13923.6 RLN89861.1 - 4.7e-12 45.5 9.5 7.4e-12 44.9 9.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN89861.1 - 5e-09 36.3 8.9 8.5e-09 35.6 8.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RLN89861.1 - 9e-08 31.9 10.0 1.6e-07 31.1 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN89861.1 - 3.2e-07 30.1 9.7 5.3e-07 29.4 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN89861.1 - 5.8e-07 29.4 6.1 1.1e-06 28.5 6.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN89861.1 - 1.7e-06 27.9 9.4 2.8e-06 27.2 9.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RLN89861.1 - 9.7e-06 25.4 9.5 1.6e-05 24.6 9.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 RLN89861.1 - 1.8e-05 24.8 8.7 3.8e-05 23.8 8.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 RLN89861.1 - 4.2e-05 23.3 3.2 8.7e-05 22.3 3.2 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 RLN89861.1 - 0.0015 18.8 8.1 0.0038 17.5 8.1 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 RLN89861.1 - 0.0047 16.7 5.3 0.011 15.5 5.3 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 RLN89861.1 - 0.015 15.1 5.4 0.026 14.3 5.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 RLN89861.1 - 0.02 15.0 7.3 0.035 14.2 7.3 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 YL1 PF05764.13 RLN89861.1 - 0.052 13.6 2.2 0.067 13.3 2.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Myc_N PF01056.18 RLN89861.1 - 0.056 13.3 0.4 0.12 12.2 0.4 1.6 1 0 0 1 1 1 0 Myc amino-terminal region Nop14 PF04147.12 RLN89861.1 - 0.062 11.5 1.9 0.073 11.3 1.9 1.1 1 0 0 1 1 1 0 Nop14-like family zf-RING_11 PF17123.5 RLN89861.1 - 0.12 12.1 6.0 0.26 11.0 6.0 1.6 1 0 0 1 1 1 0 RING-like zinc finger Utp14 PF04615.13 RLN89861.1 - 0.14 10.7 1.9 0.16 10.5 1.9 1.1 1 0 0 1 1 1 0 Utp14 protein CDC45 PF02724.14 RLN89861.1 - 0.16 10.2 3.8 0.21 9.8 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Rubredoxin_2 PF18073.1 RLN89861.1 - 0.17 11.6 1.4 0.34 10.7 1.4 1.5 1 0 0 1 1 1 0 Rubredoxin metal binding domain FAM176 PF14851.6 RLN89861.1 - 0.46 10.1 3.4 0.94 9.1 3.4 1.4 1 0 0 1 1 1 0 FAM176 family zinc-ribbons_6 PF07191.12 RLN89861.1 - 0.68 9.9 5.2 1.3 9.0 5.2 1.5 1 1 0 1 1 1 0 zinc-ribbons CENP-B_dimeris PF09026.10 RLN89861.1 - 1.5 9.2 12.6 3.4 8.1 12.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 RLN89861.1 - 2.9 7.6 12.6 4.6 6.9 12.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-P11 PF03854.14 RLN89861.1 - 3.4 7.4 7.3 7.2 6.4 7.3 1.6 1 1 0 1 1 1 0 P-11 zinc finger LRS4 PF10422.9 RLN89861.1 - 6.3 6.3 8.2 14 5.2 8.1 1.7 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 RabGAP-TBC PF00566.18 RLN89862.1 - 1.1e-17 64.4 5.8 6.4e-17 61.9 0.0 3.0 3 0 0 3 3 3 2 Rab-GTPase-TBC domain Dehalogenase PF13486.6 RLN89862.1 - 0.087 12.2 1.7 0.14 11.5 1.7 1.2 1 0 0 1 1 1 0 Reductive dehalogenase subunit NACHT PF05729.12 RLN89863.1 - 1.5e-07 31.5 0.1 3.2e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 RLN89863.1 - 0.0026 18.2 2.8 0.011 16.2 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain Dynamitin PF04912.14 RLN89863.1 - 0.0028 17.1 2.7 0.0068 15.8 2.6 1.7 1 1 0 1 1 1 1 Dynamitin AAA_22 PF13401.6 RLN89863.1 - 0.028 14.7 0.1 0.18 12.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain KORA PF16509.5 RLN89863.1 - 0.097 13.0 0.2 0.54 10.6 0.4 2.2 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor Tmemb_cc2 PF10267.9 RLN89863.1 - 10 5.2 12.2 1.3 8.1 2.1 2.3 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein CNOT1_CAF1_bind PF16415.5 RLN89865.1 - 1.6e-89 299.1 4.8 2.3e-88 295.4 1.4 2.4 2 0 0 2 2 2 2 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 RLN89865.1 - 6.8e-56 188.3 0.7 6.8e-56 188.3 0.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 RLN89865.1 - 2.4e-55 186.7 0.1 6.1e-55 185.3 0.1 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 RLN89865.1 - 3.1e-23 82.5 0.1 8.3e-23 81.1 0.1 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat TrbI PF03743.14 RLN89865.1 - 1.5 8.6 4.1 52 3.6 0.0 2.7 3 0 0 3 3 3 0 Bacterial conjugation TrbI-like protein GCP_C_terminal PF04130.13 RLN89866.1 - 3.9e-11 43.0 0.3 5.7e-11 42.4 0.3 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Pyr_redox_2 PF07992.14 RLN89867.1 - 1.3e-50 172.3 0.0 2.2e-50 171.5 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 RLN89867.1 - 7.6e-23 80.9 0.0 2e-22 79.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 RLN89867.1 - 7.6e-16 58.4 2.2 1.1e-12 48.4 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RLN89867.1 - 1.4e-14 54.1 0.1 6.4e-11 42.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 RLN89867.1 - 3.4e-06 26.4 0.5 6.7e-05 22.1 1.2 2.5 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 RLN89867.1 - 0.00019 20.8 0.1 0.27 10.5 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 RLN89867.1 - 0.0006 18.6 0.1 0.0029 16.4 0.1 2.1 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 RLN89867.1 - 0.005 16.1 2.1 0.0053 16.0 0.3 1.9 3 0 0 3 3 3 1 Thi4 family DAO PF01266.24 RLN89867.1 - 0.017 14.8 0.9 0.11 12.1 0.4 2.5 2 2 1 3 3 3 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 RLN89867.1 - 0.037 13.4 0.9 0.065 12.6 0.5 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 RLN89867.1 - 0.066 12.3 0.4 0.13 11.4 0.4 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 RLN89867.1 - 0.38 11.0 2.9 0.49 10.7 0.2 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Complex1_LYR PF05347.15 RLN89868.1 - 7.3e-07 29.1 0.1 1.2e-06 28.4 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) ING PF12998.7 RLN89868.1 - 0.0003 21.3 0.1 0.00048 20.7 0.0 1.4 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Complex1_LYR_2 PF13233.6 RLN89868.1 - 0.001 19.8 1.0 0.0016 19.1 1.0 1.6 1 1 0 1 1 1 1 Complex1_LYR-like DUF4467 PF14729.6 RLN89868.1 - 0.14 12.5 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function with cystatin-like fold (DUF4467) PH PF00169.29 RLN89869.1 - 6.2e-07 29.9 0.0 1.2e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF5089 PF17002.5 RLN89869.1 - 0.0061 16.4 2.0 0.52 10.2 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF5089) IFT57 PF10498.9 RLN89869.1 - 0.088 11.8 1.2 0.16 10.9 1.2 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF16 PF01519.16 RLN89869.1 - 0.17 12.4 0.5 9.6 6.8 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 Tropomyosin PF00261.20 RLN89869.1 - 0.28 10.5 10.7 0.06 12.7 3.8 2.2 2 0 0 2 2 2 0 Tropomyosin SlyX PF04102.12 RLN89869.1 - 0.71 10.5 6.3 1.8 9.3 4.8 2.4 2 0 0 2 2 2 0 SlyX DUF812 PF05667.11 RLN89869.1 - 0.88 8.4 8.2 1.8 7.3 8.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) TMF_TATA_bd PF12325.8 RLN89869.1 - 1.3 9.3 7.8 1.1 9.5 2.4 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding COG2 PF06148.11 RLN89869.1 - 3.5 7.7 5.1 13 5.9 1.6 2.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 IQ PF00612.27 RLN89870.1 - 3.3e-06 26.4 3.2 0.0019 17.8 1.7 3.0 2 0 0 2 2 2 2 IQ calmodulin-binding motif Ribonuclease_T2 PF00445.18 RLN89872.1 - 1.2e-21 77.8 0.0 1.6e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family ABATE PF07336.11 RLN89872.1 - 0.005 17.5 0.6 0.0083 16.8 0.6 1.3 1 0 0 1 1 1 1 Putative stress-induced transcription regulator Peptidase_M3 PF01432.20 RLN89873.1 - 1.7e-89 301.2 0.7 2.3e-89 300.8 0.1 1.5 2 0 0 2 2 2 1 Peptidase family M3 Glucosamine_iso PF01182.20 RLN89873.1 - 3.5e-48 164.4 0.0 1.1e-25 90.9 0.0 2.6 1 1 1 2 2 2 2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Peptidase_M50B PF13398.6 RLN89873.1 - 0.33 10.6 2.2 0.61 9.7 0.2 2.2 2 0 0 2 2 2 0 Peptidase M50B-like CCDC24 PF15669.5 RLN89874.1 - 0.0056 16.6 1.0 0.0059 16.5 1.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family SIKE PF05769.11 RLN89874.1 - 0.0095 15.9 4.2 0.054 13.4 4.2 1.8 1 1 0 1 1 1 1 SIKE family Med10 PF09748.9 RLN89874.1 - 0.018 15.0 0.2 0.024 14.6 0.2 1.1 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex Prominin PF05478.11 RLN89874.1 - 0.019 13.0 1.1 0.022 12.8 1.1 1.0 1 0 0 1 1 1 0 Prominin YabA PF06156.13 RLN89874.1 - 0.026 15.2 2.5 0.036 14.7 2.5 1.1 1 0 0 1 1 1 0 Initiation control protein YabA Phage_GPO PF05929.11 RLN89874.1 - 0.098 12.3 1.3 0.11 12.1 1.3 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase FUSC PF04632.12 RLN89874.1 - 0.11 11.0 4.2 0.13 10.8 4.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tox-ODYAM1 PF15642.6 RLN89874.1 - 0.12 11.3 0.2 0.14 11.1 0.2 1.0 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus OmpH PF03938.14 RLN89874.1 - 0.13 12.6 4.2 0.16 12.3 4.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FeoB_Cyto PF17910.1 RLN89874.1 - 0.14 12.7 1.5 0.18 12.3 1.5 1.2 1 0 0 1 1 1 0 FeoB cytosolic helical domain Rpn3_C PF08375.11 RLN89874.1 - 0.26 11.8 5.0 0.39 11.2 5.0 1.3 1 0 0 1 1 1 0 Proteasome regulatory subunit C-terminal DUF2937 PF11157.8 RLN89874.1 - 0.3 10.8 2.4 0.39 10.4 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) betaPIX_CC PF16523.5 RLN89874.1 - 5.8 6.8 8.8 2 8.3 4.4 1.9 1 1 1 2 2 2 0 betaPIX coiled coil DUF1003 PF06210.11 RLN89874.1 - 6 7.0 5.6 7.8 6.7 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) WD40 PF00400.32 RLN89875.1 - 2.5e-15 56.6 5.9 0.0026 18.5 0.1 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 RLN89875.1 - 6.1e-08 31.8 3.0 3.9e-05 22.5 1.1 2.5 1 1 0 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 RLN89875.1 - 1.4e-07 31.7 0.3 0.0023 18.2 0.5 4.2 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RLN89875.1 - 0.034 14.0 0.2 0.19 11.6 0.1 2.2 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A CALM_bind PF16025.5 RLN89875.1 - 5.3 7.6 13.5 0.75 10.3 3.9 3.1 3 0 0 3 3 3 0 Calcium-dependent calmodulin binding AAA_5 PF07728.14 RLN89876.1 - 1e-31 109.8 0.0 1.6e-17 63.8 0.0 3.8 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 RLN89876.1 - 2.5e-15 56.6 0.1 3.7e-14 52.8 0.0 2.7 3 0 0 3 3 3 1 Midasin AAA lid domain AAA_7 PF12775.7 RLN89876.1 - 6.8e-12 45.3 0.0 9.4e-06 25.3 0.1 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_16 PF13191.6 RLN89876.1 - 7.5e-09 36.2 2.4 0.0038 17.6 0.0 4.0 4 1 0 4 4 4 2 AAA ATPase domain AAA_6 PF12774.7 RLN89876.1 - 2.5e-08 33.3 0.6 0.00014 21.0 0.0 2.9 3 0 0 3 3 2 2 Hydrolytic ATP binding site of dynein motor region AAA PF00004.29 RLN89876.1 - 1.1e-06 29.1 0.0 0.012 16.0 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RLN89876.1 - 1.8e-06 27.7 0.0 0.068 12.9 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Viral_helicase1 PF01443.18 RLN89876.1 - 2.8e-06 27.3 0.1 0.0087 15.8 0.0 2.8 3 0 0 3 3 2 2 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 RLN89876.1 - 1.2e-05 24.7 0.2 0.025 13.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.6 RLN89876.1 - 1.5e-05 25.3 0.7 0.051 13.9 0.1 2.8 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 RLN89876.1 - 1.6e-05 25.2 0.0 0.073 13.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 RLN89876.1 - 1.9e-05 24.7 0.2 0.25 11.2 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain TsaE PF02367.17 RLN89876.1 - 4.8e-05 23.4 0.2 0.018 15.1 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 RLN89876.1 - 6e-05 23.1 0.0 0.72 9.9 0.0 4.1 3 1 1 4 4 3 1 AAA domain Dynein_heavy PF03028.15 RLN89876.1 - 6.6e-05 23.0 0.0 0.26 11.4 0.0 2.9 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain Sigma54_activ_2 PF14532.6 RLN89876.1 - 0.00012 22.3 0.1 1.5 8.9 0.0 3.5 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_3 PF07726.11 RLN89876.1 - 0.00012 21.9 0.0 0.014 15.3 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RLN89876.1 - 0.00018 22.1 0.0 0.3 11.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 RLN89876.1 - 0.00021 21.3 0.1 0.33 10.9 0.1 3.1 3 0 0 3 3 2 1 NACHT domain RsgA_GTPase PF03193.16 RLN89876.1 - 0.00042 20.3 0.0 0.2 11.6 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 RLN89876.1 - 0.00047 20.7 0.1 0.069 13.7 0.0 2.8 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.22 RLN89876.1 - 0.00056 20.3 0.0 0.087 13.2 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 RLN89876.1 - 0.0011 18.6 3.1 0.2 11.2 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 RLN89876.1 - 0.0012 19.1 1.4 2 8.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain tRNA_lig_kinase PF08303.11 RLN89876.1 - 0.0019 18.3 0.1 0.082 13.0 0.0 2.5 2 0 0 2 2 2 1 tRNA ligase kinase domain PduV-EutP PF10662.9 RLN89876.1 - 0.0019 18.0 0.0 0.066 13.0 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 RLN89876.1 - 0.0041 16.8 0.1 2.3 7.8 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 RLN89876.1 - 0.0075 16.2 0.0 2.6 7.9 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_23 PF13476.6 RLN89876.1 - 0.0079 16.7 0.1 0.027 15.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain DUF853 PF05872.12 RLN89876.1 - 0.014 14.1 0.1 1.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) DUF815 PF05673.13 RLN89876.1 - 0.028 13.6 0.5 2.7 7.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 RLN89876.1 - 0.035 13.5 0.2 5.8 6.2 0.1 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.25 RLN89876.1 - 0.037 13.7 0.1 1.6 8.3 0.0 2.6 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.6 RLN89876.1 - 0.043 14.0 0.2 8.3 6.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain UvrD-helicase PF00580.21 RLN89876.1 - 0.045 13.3 0.1 2.9 7.3 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain PRK PF00485.18 RLN89876.1 - 0.046 13.4 0.7 7.9 6.2 0.0 3.0 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 RLN89876.1 - 0.05 13.3 0.0 4.8 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 RLN89876.1 - 0.055 13.2 0.1 0.6 9.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 RLN89876.1 - 0.057 13.2 0.1 0.23 11.2 0.0 2.0 2 0 0 2 2 1 0 IstB-like ATP binding protein TniB PF05621.11 RLN89876.1 - 0.061 12.7 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 RLN89876.1 - 0.069 12.5 1.7 7.8 5.8 0.1 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family G-alpha PF00503.20 RLN89876.1 - 0.095 11.8 0.1 5.6 6.0 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit CbiA PF01656.23 RLN89876.1 - 0.12 12.4 2.2 5.4 7.1 0.0 2.7 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ank_2 PF12796.7 RLN89877.1 - 2.3e-40 137.1 8.4 4.7e-08 33.5 0.4 8.4 3 2 7 10 10 10 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN89877.1 - 2.5e-38 130.0 10.1 5.2e-05 23.7 0.1 10.3 10 1 0 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN89877.1 - 8.9e-32 108.7 25.3 0.00048 20.4 0.1 15.4 8 3 8 16 16 16 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN89877.1 - 5.3e-24 81.7 9.8 2.2 9.1 0.0 16.2 18 0 0 18 18 18 5 Ankyrin repeat Ank PF00023.30 RLN89877.1 - 1.1e-05 25.6 6.7 64 4.2 0.1 9.6 8 3 1 9 9 9 0 Ankyrin repeat DUF5049 PF16468.5 RLN89877.1 - 0.0026 17.6 0.0 54 3.8 0.0 5.3 5 1 1 6 6 6 0 Domain of unknown function (DUF5049) DUF3322 PF11795.8 RLN89877.1 - 0.076 13.0 1.4 14 5.7 0.0 4.5 2 1 3 5 5 5 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) DUF1843 PF08898.10 RLN89877.1 - 0.091 13.3 5.7 48 4.6 0.0 5.5 6 0 0 6 6 6 0 Domain of unknown function (DUF1843) Antimicrobial19 PF08225.11 RLN89877.1 - 0.22 11.2 2.2 1.2 8.8 1.1 2.7 2 0 0 2 2 2 0 Pseudin antimicrobial peptide Sec63 PF02889.16 RLN89879.1 - 1.9e-84 282.8 0.0 2e-64 217.2 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 RLN89879.1 - 1.7e-13 50.7 0.0 3.8e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1071 PF06378.11 RLN89879.1 - 0.021 14.4 0.1 2.6 7.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1071) RsdA_SigD_bd PF16751.5 RLN89880.1 - 0.027 14.7 0.4 0.13 12.6 0.4 2.2 1 0 0 1 1 1 0 Anti-sigma-D factor RsdA to sigma factor binding region Pkinase PF00069.25 RLN89881.1 - 8.2e-70 235.2 0.0 1e-69 234.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89881.1 - 2.9e-37 128.4 0.0 4.7e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN89881.1 - 4.8e-05 22.8 0.0 7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN89881.1 - 0.0011 19.0 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN89881.1 - 0.0074 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RLN89881.1 - 0.021 13.8 0.0 0.03 13.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_C PF00433.24 RLN89881.1 - 0.037 14.7 0.1 0.11 13.2 0.1 1.9 1 0 0 1 1 1 0 Protein kinase C terminal domain FTA2 PF13095.6 RLN89881.1 - 0.082 12.5 0.0 0.14 11.8 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 FAD_binding_2 PF00890.24 RLN89881.1 - 0.11 11.5 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain MIF PF01187.18 RLN89882.1 - 3.2e-19 69.3 0.1 3.6e-19 69.2 0.1 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 RLN89882.1 - 1.1e-07 31.6 0.4 1.2e-05 25.1 0.0 2.2 2 0 0 2 2 2 2 Tautomerase enzyme TrmB PF01978.19 RLN89882.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Tau95_N PF17682.1 RLN89883.1 - 7.1e-22 78.0 1.2 2.2e-21 76.4 0.0 2.4 2 0 0 2 2 2 1 Tau95 Triple barrel domain Tau95 PF09734.9 RLN89883.1 - 1.4e-21 77.8 0.5 3.4e-21 76.5 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Nop14 PF04147.12 RLN89883.1 - 2.7 6.1 29.7 4.6 5.3 29.7 1.4 1 0 0 1 1 1 0 Nop14-like family TAF6_C PF07571.13 RLN89885.1 - 2.9e-23 82.0 0.1 5.7e-22 77.9 0.0 2.6 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 RLN89885.1 - 2e-16 59.9 0.0 4.5e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 RLN89885.1 - 0.048 13.7 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit HEAT PF02985.22 RLN89885.1 - 0.1 12.9 0.1 2.7 8.5 0.1 2.9 2 0 0 2 2 2 0 HEAT repeat Glyco_hydro_17 PF00332.18 RLN89886.1 - 0.11 12.0 0.3 0.26 10.9 0.1 1.6 1 1 1 2 2 2 0 Glycosyl hydrolases family 17 Metallophos PF00149.28 RLN89887.1 - 4.6e-17 63.2 0.0 8.3e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase BBS1 PF14779.6 RLN89888.1 - 8.9e-12 45.0 0.2 2.2e-11 43.7 0.1 1.7 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.6 RLN89888.1 - 0.00016 21.6 0.0 0.11 12.5 0.0 2.2 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region NUP214 PF16755.5 RLN89888.1 - 0.023 13.9 0.1 0.13 11.5 0.1 1.8 1 1 1 2 2 2 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 PPPI_inhib PF14895.6 RLN89888.1 - 0.067 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 1 inhibitor FYVE PF01363.21 RLN89889.1 - 0.017 15.3 17.2 0.039 14.1 17.2 1.7 1 0 0 1 1 1 0 FYVE zinc finger C1_1 PF00130.22 RLN89889.1 - 0.42 10.5 8.2 1.1 9.2 8.2 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 RLN89889.1 - 2.9 8.2 12.3 6.9 6.9 12.2 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger LRR_8 PF13855.6 RLN89890.1 - 3e-30 103.8 29.7 5e-09 35.8 5.5 5.9 1 1 6 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 RLN89890.1 - 2.4e-27 94.5 36.6 2.9e-08 33.9 2.4 7.3 4 2 4 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN89890.1 - 4.5e-12 44.7 25.8 1.8 9.4 0.4 11.2 12 0 0 12 12 12 4 Leucine Rich Repeat LRR_9 PF14580.6 RLN89890.1 - 2.1e-08 33.8 14.1 1.5e-05 24.6 1.7 4.5 1 1 3 5 5 5 4 Leucine-rich repeat LRR_6 PF13516.6 RLN89890.1 - 0.0057 16.6 24.0 2.2 8.5 0.0 9.1 10 0 0 10 10 10 1 Leucine Rich repeat DUF2322 PF10084.9 RLN89890.1 - 0.036 14.1 0.2 0.11 12.5 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2322) A_thal_3526 PF09713.10 RLN89891.1 - 6.9e-22 77.5 0.2 1.1e-21 76.9 0.2 1.3 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) LRR_9 PF14580.6 RLN89892.1 - 1.9e-14 53.6 1.5 1.9e-09 37.3 0.0 2.5 1 1 1 2 2 2 2 Leucine-rich repeat C2 PF00168.30 RLN89892.1 - 8.7e-14 51.7 0.0 1.2e-12 48.0 0.0 2.5 2 0 0 2 2 2 1 C2 domain LRR_8 PF13855.6 RLN89892.1 - 2.5e-10 40.0 12.5 2.1e-09 37.0 6.5 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 RLN89892.1 - 1.9e-07 31.3 13.6 0.00028 21.2 1.2 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) BBS2_C PF14782.6 RLN89892.1 - 0.052 12.3 1.4 0.48 9.1 0.9 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal LRR_6 PF13516.6 RLN89892.1 - 0.33 11.1 3.0 86 3.6 0.3 4.2 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 RLN89892.1 - 0.53 11.0 6.2 26 5.9 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat DUF349 PF03993.12 RLN89892.1 - 9.5 6.6 10.1 2.6 8.4 5.9 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) HSP70 PF00012.20 RLN89893.1 - 2.2e-42 145.0 1.6 1.8e-33 115.6 0.0 2.7 3 0 0 3 3 3 2 Hsp70 protein KIAA1430 PF13879.6 RLN89893.1 - 2.7e-09 37.7 3.7 2.7e-09 37.7 3.7 2.3 1 1 1 2 2 2 1 KIAA1430 homologue ATP-synt_Z PF16594.5 RLN89893.1 - 0.016 14.7 0.1 0.032 13.7 0.1 1.4 1 0 0 1 1 1 0 Putative AtpZ or ATP-synthase-associated Methyltransf_23 PF13489.6 RLN89894.1 - 0.057 13.3 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain BUD22 PF09073.10 RLN89894.1 - 2.4 7.4 31.8 3.5 6.9 15.5 2.1 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 RLN89894.1 - 5.2 5.2 30.1 2.2 6.4 2.9 2.0 2 0 0 2 2 2 0 Nop14-like family TetR_C_33 PF13305.6 RLN89895.1 - 0.03 15.0 0.0 0.047 14.4 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Na_H_antiporter PF03553.14 RLN89896.1 - 5.5e-36 124.3 6.3 5.5e-36 124.3 6.3 2.5 2 0 0 2 2 2 1 Na+/H+ antiporter family COX2_TM PF02790.15 RLN89896.1 - 0.012 15.7 0.1 0.24 11.6 0.0 3.2 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain Acetyltransf_10 PF13673.7 RLN89897.1 - 2e-12 47.1 0.0 2.3e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN89897.1 - 4.2e-08 33.5 0.0 5.4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RLN89897.1 - 7.5e-07 29.4 0.1 1e-06 29.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 RLN89897.1 - 0.0012 19.5 1.3 0.028 15.1 0.1 2.6 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 RLN89897.1 - 0.0054 16.8 0.1 0.011 15.8 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Ad_Cy_reg PF16701.5 RLN89897.1 - 0.14 11.9 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase regulatory domain Acetyltransf_10 PF13673.7 RLN89898.1 - 1.4e-12 47.6 0.0 1.7e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN89898.1 - 2.4e-09 37.5 0.0 3e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RLN89898.1 - 1.4e-08 35.0 0.0 1.9e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 RLN89898.1 - 0.00023 21.0 0.0 0.00037 20.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 RLN89898.1 - 0.0084 16.2 0.0 0.032 14.3 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 RLN89898.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF1488 PF07369.11 RLN89900.1 - 1.1 9.3 9.1 9.2 6.3 2.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) FAR1 PF03101.15 RLN89901.1 - 0.058 14.1 0.3 0.13 12.9 0.3 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain Osteoregulin PF07175.11 RLN89901.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Osteoregulin Citrate_ly_lig PF08218.11 RLN89901.1 - 0.16 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain DUF5575 PF17738.1 RLN89901.1 - 0.17 10.9 4.8 2.1 7.3 4.8 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5575) EPSP_synthase PF00275.20 RLN89902.1 - 2.9e-125 418.2 0.1 4.6e-125 417.6 0.1 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 RLN89902.1 - 5.8e-95 317.4 1.1 6.7e-95 317.2 0.1 1.7 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 RLN89902.1 - 8.3e-45 153.8 0.0 1.5e-44 152.9 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 RLN89902.1 - 8.9e-27 94.1 0.0 2.6e-25 89.4 0.0 2.8 2 0 0 2 2 2 1 Shikimate kinase Fe-ADH_2 PF13685.6 RLN89902.1 - 4.2e-12 46.3 0.0 1.1e-11 44.9 0.0 1.8 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_33 PF13671.6 RLN89902.1 - 0.00016 21.9 0.0 0.0079 16.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain Fe-ADH PF00465.19 RLN89902.1 - 0.00025 20.0 0.3 0.00095 18.1 0.1 2.0 3 0 0 3 3 3 1 Iron-containing alcohol dehydrogenase AAA_16 PF13191.6 RLN89902.1 - 0.0013 19.1 0.0 0.0084 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 RLN89902.1 - 0.081 13.5 0.0 1.2 9.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 RLN89902.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 RLN89902.1 - 0.19 10.9 0.2 0.5 9.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Shikimate_dh_N PF08501.11 RLN89903.1 - 6.1e-20 71.3 0.0 1.2e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 RLN89903.1 - 1.7e-10 41.1 0.0 2.6e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SIS_2 PF13580.6 RLN89903.1 - 0.00055 20.0 0.1 0.00098 19.2 0.1 1.3 1 0 0 1 1 1 1 SIS domain SDH_C PF18317.1 RLN89903.1 - 0.00075 19.2 2.1 0.00084 19.1 0.1 2.2 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain F420_oxidored PF03807.17 RLN89903.1 - 0.0078 16.8 0.2 0.014 16.0 0.2 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 RLN89903.1 - 0.085 12.1 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase E1-E2_ATPase PF00122.20 RLN89904.1 - 3.7e-47 160.2 1.7 1.2e-46 158.5 1.7 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 RLN89904.1 - 2e-17 64.2 0.0 7.4e-17 62.3 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RLN89904.1 - 6.3e-15 54.6 0.1 1.3e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RLN89904.1 - 0.00018 21.4 0.6 0.00045 20.0 0.2 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN89904.1 - 0.0069 16.4 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Phage_holin_Dp1 PF16938.5 RLN89904.1 - 0.14 12.4 2.6 4.6 7.5 1.2 2.7 2 0 0 2 2 2 0 Putative phage holin Dp-1 Aph-1 PF06105.12 RLN89905.1 - 4.1e-44 150.7 13.9 6.3e-44 150.1 13.9 1.1 1 0 0 1 1 1 1 Aph-1 protein DUF4181 PF13789.6 RLN89905.1 - 0.042 14.1 0.7 0.098 12.9 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) YadA_anchor PF03895.15 RLN89905.1 - 6.3 7.0 6.9 0.71 10.0 0.2 2.4 2 0 0 2 2 2 0 YadA-like membrane anchor domain zf-CCHC PF00098.23 RLN89906.1 - 0.0028 17.7 4.8 0.0041 17.1 4.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 RLN89906.1 - 0.13 12.1 3.1 0.25 11.2 3.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 RLN89906.1 - 0.41 10.4 2.0 0.75 9.6 2.0 1.4 1 0 0 1 1 1 0 Zinc knuckle DDE_1 PF03184.19 RLN89907.1 - 0.073 12.7 0.0 0.073 12.7 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN89908.1 - 8.6e-08 32.1 0.0 5e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain BK_channel_a PF03493.18 RLN89910.1 - 3.5e-20 72.0 0.0 2.4e-19 69.3 0.0 2.2 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit TrkA_N PF02254.18 RLN89910.1 - 6e-07 29.7 3.4 0.014 15.6 0.0 3.1 4 0 0 4 4 4 2 TrkA-N domain Castor_Poll_mid PF06241.12 RLN89910.1 - 0.023 14.7 0.0 0.28 11.2 0.0 2.4 2 0 0 2 2 2 0 Castor and Pollux, part of voltage-gated ion channel TrkA_C PF02080.21 RLN89910.1 - 0.094 12.6 0.0 21 5.0 0.0 2.8 2 0 0 2 2 2 0 TrkA-C domain HECT PF00632.25 RLN89911.1 - 5e-72 243.0 0.0 7.7e-72 242.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 RLN89911.1 - 0.0001 21.5 3.2 0.00019 20.7 3.2 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 RLN89911.1 - 0.016 14.5 0.2 0.035 13.5 0.2 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain CSN8_PSD8_EIF3K PF10075.9 RLN89912.1 - 2.6e-16 59.9 0.0 5.7e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 RLN89912.1 - 0.0068 15.8 0.1 0.0096 15.3 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP family DUF3243 PF11588.8 RLN89913.1 - 0.13 12.6 0.1 0.73 10.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3243) RecO_N PF11967.8 RLN89913.1 - 0.14 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Recombination protein O N terminal Aa_trans PF01490.18 RLN89914.1 - 1.6e-55 188.5 19.6 2.1e-55 188.1 19.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1129 PF06570.11 RLN89914.1 - 0.31 10.5 8.7 0.045 13.2 1.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Chromo PF00385.24 RLN89915.1 - 1.4e-07 31.3 0.1 1.4e-07 31.3 0.1 3.4 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain SnoaL_2 PF12680.7 RLN89916.1 - 0.0059 17.2 0.0 0.011 16.4 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain Pkinase_Tyr PF07714.17 RLN89918.1 - 3.9e-29 101.7 0.0 5.9e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN89918.1 - 4.5e-26 91.8 0.0 7.7e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RLN89918.1 - 0.0007 19.0 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like CAP_GLY PF01302.25 RLN89919.1 - 0.054 13.5 0.1 0.083 12.9 0.1 1.3 1 0 0 1 1 1 0 CAP-Gly domain MFS_1_like PF12832.7 RLN89920.1 - 6.5e-64 216.2 15.4 1.1e-63 215.4 15.4 1.3 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RLN89920.1 - 6.5e-20 71.3 28.5 1.6e-19 70.1 25.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 RLN89920.1 - 6.6e-15 54.8 11.3 2.3e-14 53.0 11.3 1.7 1 1 0 1 1 1 1 LacY proton/sugar symporter Nuc_H_symport PF03825.16 RLN89920.1 - 2.2e-12 46.7 11.7 8.5e-12 44.8 11.7 1.7 1 1 0 1 1 1 1 Nucleoside H+ symporter MFS_2 PF13347.6 RLN89920.1 - 1.3e-06 27.3 19.2 2e-06 26.7 16.9 2.2 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_3 PF05977.13 RLN89920.1 - 0.014 13.8 10.4 0.029 12.8 10.4 1.4 1 1 0 1 1 1 0 Transmembrane secretion effector MFS_1 PF07690.16 RLN89921.1 - 0.0027 16.7 0.2 0.0028 16.6 0.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 RLN89921.1 - 0.0029 16.5 0.3 0.0032 16.4 0.3 1.0 1 0 0 1 1 1 1 MFS_1 like family GSHPx PF00255.19 RLN89924.1 - 1.5e-38 130.7 0.6 1.5e-38 130.7 0.6 1.7 2 0 0 2 2 2 1 Glutathione peroxidase AhpC-TSA PF00578.21 RLN89924.1 - 1.6e-08 34.5 0.1 3.7e-08 33.3 0.1 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RLN89924.1 - 2.7e-05 23.9 0.0 5.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Redoxin GSHPx PF00255.19 RLN89925.1 - 3.6e-38 129.5 2.2 5.1e-38 129.0 0.6 1.9 2 0 0 2 2 2 1 Glutathione peroxidase AhpC-TSA PF00578.21 RLN89925.1 - 1.4e-08 34.6 0.1 2.7e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RLN89925.1 - 3e-05 23.8 0.0 5.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Redoxin GSHPx PF00255.19 RLN89926.1 - 6.9e-36 122.1 0.3 1.3e-35 121.2 0.3 1.5 1 0 0 1 1 1 1 Glutathione peroxidase PH PF00169.29 RLN89926.1 - 4.4e-06 27.1 0.0 0.017 15.6 0.0 2.6 2 0 0 2 2 2 2 PH domain AhpC-TSA PF00578.21 RLN89926.1 - 2.6e-05 24.1 0.3 0.00012 21.9 0.0 2.1 2 0 0 2 2 2 1 AhpC/TSA family DUF3019 PF11456.8 RLN89926.1 - 0.002 18.6 0.3 2 8.9 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF3019) Redoxin PF08534.10 RLN89926.1 - 0.014 15.1 0.1 0.056 13.2 0.0 2.0 2 0 0 2 2 2 0 Redoxin FYVE PF01363.21 RLN89927.1 - 6.4e-06 26.2 8.6 1.2e-05 25.3 8.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN89927.1 - 4.4 7.5 8.9 0.23 11.7 2.9 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger DUF2757 PF10955.8 RLN89927.1 - 6.5 7.1 6.6 1.5 9.1 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) GSHPx PF00255.19 RLN89928.1 - 6.5e-21 73.9 0.0 1e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.19 RLN89929.1 - 1.8e-37 127.2 0.8 3.9e-37 126.1 0.8 1.6 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 RLN89929.1 - 5.5e-06 26.3 0.1 1.5e-05 24.9 0.1 1.8 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RLN89929.1 - 0.00057 19.6 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Redoxin DUF4461 PF14688.6 RLN89929.1 - 0.091 12.5 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) Presenilin PF01080.17 RLN89929.1 - 0.73 8.5 7.9 0.023 13.5 0.8 1.8 2 0 0 2 2 2 0 Presenilin Spore_coat_CotO PF14153.6 RLN89929.1 - 3.6 7.5 34.6 0.13 12.2 17.4 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Pkinase PF00069.25 RLN89930.1 - 1.8e-43 148.8 0.0 5.4e-29 101.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89930.1 - 3.6e-43 147.7 0.0 5.2e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN89930.1 - 0.035 12.9 1.0 0.1 11.4 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Mito_carr PF00153.27 RLN89931.1 - 5e-48 161.0 6.9 3.3e-15 55.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DSPn PF14671.6 RLN89933.1 - 7.8e-32 110.6 0.0 1.4e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 RLN89933.1 - 2.5e-13 50.0 0.0 4e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RLN89933.1 - 5.5e-06 26.6 0.0 7.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 RLN89933.1 - 2e-05 24.3 0.0 3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RLN89933.1 - 0.014 15.4 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Voltage_CLC PF00654.20 RLN89934.1 - 1.5e-07 31.0 4.7 4.3e-07 29.5 4.7 1.8 1 0 0 1 1 1 1 Voltage gated chloride channel Dehydratase_SU PF02287.15 RLN89934.1 - 0.19 11.8 0.7 22 5.2 0.1 2.7 2 0 0 2 2 2 0 Dehydratase small subunit Myc-LZ PF02344.15 RLN89934.1 - 4.9 7.3 7.2 31 4.8 0.8 3.0 2 0 0 2 2 2 0 Myc leucine zipper domain Ras PF00071.22 RLN89935.1 - 3e-32 111.4 0.0 4e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN89935.1 - 1.5e-16 60.7 0.0 2.2e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN89935.1 - 1.4e-05 24.6 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RLN89935.1 - 0.0055 16.8 0.0 0.0086 16.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RLN89935.1 - 0.012 15.9 0.1 0.019 15.3 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 RLN89935.1 - 0.035 14.4 0.0 0.14 12.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 RLN89935.1 - 0.097 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MCM PF00493.23 RLN89935.1 - 0.19 10.8 0.0 0.38 9.8 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain Carboxyl_trans PF01039.22 RLN89936.1 - 2.9e-22 79.0 0.1 3.6e-22 78.7 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain SMN PF06003.12 RLN89938.1 - 0.00018 20.9 12.3 0.00018 20.9 12.3 2.4 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) CDK2AP PF09806.9 RLN89938.1 - 0.087 12.9 10.6 0.12 12.4 10.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein WASH-7_mid PF14744.6 RLN89939.1 - 3.3e-147 490.1 6.7 3.3e-147 490.1 6.7 1.7 2 0 0 2 2 2 1 WASH complex subunit 7 WASH-7_N PF14745.6 RLN89939.1 - 1.4e-121 406.8 0.0 1.4e-120 403.6 0.0 2.0 1 1 0 1 1 1 1 WASH complex subunit 7, N-terminal WASH-7_C PF14746.6 RLN89939.1 - 3.9e-62 209.0 2.6 8.5e-62 207.9 2.6 1.6 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal DUF2379 PF09543.10 RLN89940.1 - 0.042 14.0 1.0 0.079 13.1 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) zf-C2H2_6 PF13912.6 RLN89940.1 - 0.073 13.1 0.4 0.16 12.0 0.1 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RLN89941.1 - 0.14 12.2 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger Herpes_pp85 PF04637.12 RLN89941.1 - 5.2 5.4 5.5 6.9 5.0 5.5 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) SNARE PF05739.19 RLN89942.1 - 2.5e-06 27.4 0.3 9.1e-06 25.6 0.1 1.9 2 0 0 2 2 2 1 SNARE domain SipA PF09052.10 RLN89942.1 - 0.0019 17.9 0.4 0.0023 17.6 0.4 1.2 1 0 0 1 1 1 1 SipA N-terminal domain TRIQK PF15168.6 RLN89942.1 - 0.0038 17.1 0.1 0.0058 16.5 0.1 1.3 1 0 0 1 1 1 1 Triple QxxK/R motif-containing protein family Synaptobrevin PF00957.21 RLN89942.1 - 0.037 13.8 3.3 0.048 13.4 0.6 2.0 1 1 1 2 2 2 0 Synaptobrevin Phage_Coat_Gp8 PF05371.12 RLN89942.1 - 0.19 11.5 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Phage major coat protein, Gp8 Orf78 PF06024.12 RLN89942.1 - 1.2 9.5 3.7 2.8 8.3 3.7 1.8 1 1 0 1 1 1 0 Orf78 (ac78) Peptidase_S9_N PF02897.15 RLN89943.1 - 3e-86 289.8 6.4 4.2e-86 289.3 6.4 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 RLN89943.1 - 4.1e-65 219.2 0.1 2.4e-64 216.7 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family DDE_3 PF13358.6 RLN89944.1 - 1.5e-08 34.6 0.0 2.4e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.20 RLN89944.1 - 0.05 13.9 0.2 0.42 11.0 0.0 2.3 2 0 0 2 2 2 0 Transposase BAH PF01426.18 RLN89945.1 - 2.1e-15 56.7 0.4 3.9e-15 55.8 0.4 1.4 1 0 0 1 1 1 1 BAH domain ELM2 PF01448.24 RLN89945.1 - 6.8e-05 23.5 0.1 0.00023 21.9 0.1 1.9 1 0 0 1 1 1 1 ELM2 domain zf-C3HC4_2 PF13923.6 RLN89946.1 - 7.6e-06 25.7 2.5 7.6e-06 25.7 2.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN89946.1 - 5.8e-05 23.0 1.0 5.8e-05 23.0 1.0 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 RLN89946.1 - 9.9e-05 22.6 2.0 9.9e-05 22.6 2.0 2.3 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 RLN89946.1 - 0.00016 21.8 1.5 0.00016 21.8 1.5 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RLN89946.1 - 0.0004 20.2 4.1 0.0011 18.7 4.1 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN89946.1 - 0.0033 17.1 0.4 0.012 15.4 0.2 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 RLN89946.1 - 0.012 15.6 0.6 0.038 14.0 0.6 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RLN89946.1 - 0.016 15.0 1.9 0.063 13.1 0.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.10 RLN89946.1 - 0.13 12.4 1.6 0.38 10.9 1.6 1.8 1 0 0 1 1 1 0 Zinc ribbon domain zf-C3HC4_2 PF13923.6 RLN89947.1 - 3.2e-07 30.1 2.0 3.2e-07 30.1 2.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN89947.1 - 1.9e-05 24.8 5.5 0.00017 21.8 5.5 2.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 RLN89947.1 - 2.5e-05 24.5 1.7 2.5e-05 24.5 1.7 2.5 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 RLN89947.1 - 0.0001 22.2 1.2 0.0001 22.2 1.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RLN89947.1 - 0.0003 20.6 4.6 0.00091 19.1 4.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN89947.1 - 0.0014 18.6 0.8 0.017 15.1 0.6 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 RLN89947.1 - 0.0027 17.4 0.4 0.0087 15.8 0.4 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 RLN89947.1 - 0.0048 16.7 1.5 0.021 14.7 0.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN89947.1 - 0.022 14.6 2.4 0.083 12.8 1.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 RLN89947.1 - 0.16 12.0 2.0 0.37 10.9 0.5 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.14 RLN89947.1 - 0.17 11.8 0.1 26 4.7 0.0 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4_4 PF15227.6 RLN89947.1 - 0.19 11.9 4.6 0.095 12.9 1.6 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Zn-ribbon_8 PF09723.10 RLN89947.1 - 2.6 8.2 6.3 1.1 9.5 1.6 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Kinesin PF00225.23 RLN89948.1 - 5.6e-90 301.6 0.0 9.6e-90 300.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN89948.1 - 1.3e-22 80.4 0.0 2.3e-21 76.3 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding RNase_PH_C PF03725.15 RLN89948.1 - 2.8e-06 27.2 0.0 1.6e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 RNase_PH PF01138.21 RLN89948.1 - 7.7e-06 26.4 0.6 3.9e-05 24.2 0.1 2.6 3 0 0 3 3 3 1 3' exoribonuclease family, domain 1 HTH_23 PF13384.6 RLN89949.1 - 3e-05 23.7 0.4 5.3e-05 22.9 0.4 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 RLN89949.1 - 0.0029 17.7 0.3 0.0058 16.7 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 RLN89949.1 - 0.0048 17.0 0.0 0.0091 16.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase CENP-B_N PF04218.13 RLN89949.1 - 0.0051 16.4 0.6 0.0077 15.9 0.6 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain YdaS_antitoxin PF15943.5 RLN89949.1 - 0.023 14.6 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_Tnp_4 PF13613.6 RLN89949.1 - 0.023 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Ank_2 PF12796.7 RLN89950.1 - 5e-06 27.0 0.0 1.1e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN89950.1 - 1.3e-05 25.7 0.0 3e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN89950.1 - 0.00098 19.4 0.1 0.002 18.4 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 RLN89950.1 - 0.031 14.7 0.1 0.12 12.9 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 RLN89950.1 - 0.055 14.0 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat FMN_dh PF01070.18 RLN89951.1 - 2e-98 329.7 3.3 9.4e-96 320.9 3.3 2.0 1 1 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 RLN89951.1 - 0.0014 18.0 0.3 0.003 16.9 0.2 1.7 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 RLN89951.1 - 0.0069 15.4 0.1 0.012 14.6 0.1 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.17 RLN89951.1 - 0.064 12.6 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase Med31 PF05669.12 RLN89954.1 - 1e-33 115.2 4.4 1.9e-25 88.7 3.6 2.0 2 0 0 2 2 2 2 SOH1 FTHFS PF01268.19 RLN89955.1 - 1.6e-215 716.5 0.1 1.2e-213 710.4 0.0 3.0 2 1 0 2 2 2 2 Formate--tetrahydrofolate ligase CbiA PF01656.23 RLN89955.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PepSY PF03413.19 RLN89955.1 - 0.16 12.6 0.0 0.41 11.3 0.0 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain CENP-T_C PF15511.6 RLN89958.1 - 1.7e-08 34.5 0.1 2.1e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 RLN89958.1 - 0.00019 21.7 0.1 0.00025 21.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 RLN89958.1 - 0.0003 20.9 0.1 0.00042 20.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 RLN89958.1 - 0.004 17.4 0.0 0.0067 16.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 RLN89958.1 - 0.0046 17.3 0.2 0.0052 17.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 RLN89958.1 - 0.027 14.5 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 RLN89958.1 - 0.053 13.5 0.1 0.079 13.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 RLN89958.1 - 0.18 11.6 0.1 0.22 11.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) AAA_16 PF13191.6 RLN89959.1 - 1.2e-13 51.8 0.1 6.9e-13 49.3 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.29 RLN89959.1 - 2.1e-09 37.9 0.0 1e-08 35.6 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN89959.1 - 7.4e-08 32.8 0.0 2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 RLN89959.1 - 1.3e-05 25.2 0.0 3.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 RLN89959.1 - 0.0017 18.7 0.2 0.013 15.8 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RLN89959.1 - 0.0018 18.0 0.1 0.012 15.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_32 PF13654.6 RLN89959.1 - 0.0068 15.2 0.0 0.2 10.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 RLN89959.1 - 0.014 15.2 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 RLN89959.1 - 0.025 14.5 0.0 0.083 12.8 0.0 1.9 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 RLN89959.1 - 0.039 13.1 0.0 0.063 12.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Cdc6_C PF09079.11 RLN89959.1 - 0.042 13.8 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain NACHT PF05729.12 RLN89959.1 - 0.056 13.4 0.1 0.17 11.8 0.1 1.9 1 1 0 1 1 1 0 NACHT domain PIF1 PF05970.14 RLN89959.1 - 0.057 12.6 0.0 0.097 11.8 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase TsaE PF02367.17 RLN89959.1 - 0.083 12.9 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 RLN89959.1 - 0.13 12.8 0.0 0.39 11.2 0.0 1.8 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 RLN89959.1 - 0.15 11.6 0.0 0.5 9.9 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 RLN89959.1 - 0.16 12.5 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Glyco_hydro81C PF17652.1 RLN89960.1 - 5.7e-113 377.7 2.4 5.7e-113 377.7 2.4 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 RLN89960.1 - 1.8e-53 181.8 2.6 3.8e-53 180.7 2.6 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain PAE PF03283.13 RLN89960.1 - 1e-09 38.0 0.7 2.6e-09 36.7 0.7 1.6 1 1 0 1 1 1 1 Pectinacetylesterase HEAT_EZ PF13513.6 RLN89961.1 - 2.1e-16 60.0 21.8 4.7e-05 23.8 0.2 11.1 10 2 2 12 12 12 3 HEAT-like repeat HEAT_2 PF13646.6 RLN89961.1 - 9.2e-16 58.0 17.0 0.00083 19.7 0.0 8.5 6 2 5 11 11 11 5 HEAT repeats HEAT PF02985.22 RLN89961.1 - 4.2e-13 48.3 25.9 5.7e-05 23.0 0.1 13.2 15 0 0 15 15 15 2 HEAT repeat IBN_N PF03810.19 RLN89961.1 - 7e-11 41.9 2.2 1.2e-06 28.3 0.6 3.1 2 0 0 2 2 2 2 Importin-beta N-terminal domain Cnd1 PF12717.7 RLN89961.1 - 4.6e-07 30.0 4.7 0.00042 20.4 0.0 5.3 6 0 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 RLN89961.1 - 5.7e-07 30.0 0.0 0.0094 16.5 0.0 4.4 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 RLN89961.1 - 0.00028 20.7 0.8 7.3 6.3 0.0 5.2 5 1 1 6 6 6 1 rRNA processing/ribosome biogenesis DUF3385 PF11865.8 RLN89961.1 - 0.0011 18.9 0.3 2.5 8.0 0.0 5.2 6 1 1 7 7 6 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 RLN89961.1 - 0.01 15.4 0.2 6.1 6.3 0.0 4.6 5 1 0 5 5 5 0 CLASP N terminal MMS19_C PF12460.8 RLN89961.1 - 0.012 14.7 0.2 0.4 9.7 0.3 2.7 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal Tti2 PF10521.9 RLN89961.1 - 0.013 15.1 0.1 0.11 12.0 0.0 2.5 2 1 1 3 3 3 0 Tti2 family Adaptin_N PF01602.20 RLN89961.1 - 0.022 13.3 0.7 9.4 4.6 0.0 4.0 4 0 0 4 4 4 0 Adaptin N terminal region CTD_bind PF04818.13 RLN89961.1 - 0.027 15.3 0.8 11 6.9 0.0 4.6 5 1 1 6 6 3 0 RNA polymerase II-binding domain. ParcG PF10274.9 RLN89961.1 - 0.049 13.7 0.9 3.7 7.6 0.0 3.9 4 1 0 5 5 5 0 Parkin co-regulated protein Importin_rep_4 PF18808.1 RLN89961.1 - 0.12 12.7 0.1 0.12 12.7 0.1 4.3 3 2 1 4 4 4 0 Importin repeat Arm PF00514.23 RLN89961.1 - 0.21 11.7 2.9 3.3 7.9 0.0 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF4611 PF15387.6 RLN89961.1 - 1.4 9.2 10.2 13 6.1 1.4 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Cupin_4 PF08007.12 RLN89962.1 - 2.1e-43 149.0 0.0 2.9e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 RLN89962.1 - 9.7e-07 28.7 0.0 0.011 15.5 0.1 2.4 2 0 0 2 2 2 2 Cupin-like domain Cupin_2 PF07883.11 RLN89962.1 - 0.027 14.2 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 Cupin domain ARD PF03079.14 RLN89962.1 - 0.083 13.1 0.1 0.41 10.8 0.0 2.2 2 0 0 2 2 2 0 ARD/ARD' family Cupin_1 PF00190.22 RLN89962.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Cupin DNA_pol_phi PF04931.13 RLN89962.1 - 1.2 7.1 11.6 2 6.4 11.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi Adaptin_N PF01602.20 RLN89963.1 - 7.9e-87 292.0 12.7 1.1e-75 255.2 10.5 2.1 1 1 1 2 2 2 2 Adaptin N terminal region COP-gamma_platf PF08752.10 RLN89963.1 - 3e-47 160.6 2.3 3e-47 160.6 0.7 1.8 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 RLN89963.1 - 5.1e-25 87.8 0.0 3.6e-24 85.1 0.0 2.2 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 RLN89963.1 - 4.2e-13 49.5 4.3 8.7e-09 35.7 0.2 4.2 3 1 1 4 4 4 3 HEAT repeats Cnd1 PF12717.7 RLN89963.1 - 1.3e-10 41.5 11.2 0.00097 19.2 1.0 4.5 2 1 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 DNA_alkylation PF08713.11 RLN89963.1 - 0.0099 15.6 0.5 0.53 10.0 0.1 3.3 3 1 1 4 4 4 1 DNA alkylation repair enzyme HEAT PF02985.22 RLN89963.1 - 0.012 15.8 10.7 24 5.5 0.2 5.9 6 0 0 6 6 6 0 HEAT repeat CmlA_N PF18456.1 RLN89963.1 - 0.046 13.0 0.1 0.084 12.2 0.1 1.3 1 0 0 1 1 1 0 Diiron non-heme beta-hydroxylase N-terminal domain Vac14_Fab1_bd PF12755.7 RLN89963.1 - 2.4 8.8 4.9 6 7.5 0.0 3.8 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.16 RLN89963.1 - 9.4 7.2 7.9 7.7 7.5 0.2 3.6 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Histone PF00125.24 RLN89964.1 - 2.4e-17 63.5 0.1 2.9e-17 63.3 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 RLN89964.1 - 0.00023 21.6 0.0 0.00041 20.8 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 RLN89964.1 - 0.0093 16.2 0.1 0.028 14.7 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 RLN89964.1 - 0.078 13.0 0.1 0.086 12.9 0.1 1.2 1 0 0 1 1 1 0 YscO-like protein Histone PF00125.24 RLN89965.1 - 2.7e-40 137.8 1.1 3.1e-40 137.6 1.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 RLN89965.1 - 0.00042 20.6 0.0 0.00059 20.2 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 RLN89965.1 - 0.00046 20.3 0.1 0.00066 19.8 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 RLN89965.1 - 0.011 15.9 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 RLN89965.1 - 0.021 14.9 0.0 0.025 14.6 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit EI24 PF07264.11 RLN89967.1 - 0.005 17.1 0.3 0.0051 17.1 0.3 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) zf-CXXC PF02008.20 RLN89968.1 - 8.8e-14 51.3 23.0 7.1e-11 42.0 14.1 2.3 2 0 0 2 2 2 2 CXXC zinc finger domain DUF3752 PF12572.8 RLN89970.1 - 6.4e-12 46.3 5.6 7.4e-12 46.0 5.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) AvrE_T3Es PF11725.8 RLN89970.1 - 0.021 12.1 1.2 0.02 12.2 1.2 1.0 1 0 0 1 1 1 0 AvrE-family Type-III effector proteins (T3Es) TPR_1 PF00515.28 RLN89971.1 - 0.00092 18.9 0.2 0.22 11.4 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN89971.1 - 0.0096 16.2 0.3 0.017 15.5 0.3 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN89971.1 - 0.015 15.8 0.6 0.026 15.1 0.6 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 RLN89971.1 - 0.026 14.7 0.1 0.039 14.1 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN89971.1 - 0.031 14.4 0.5 2 8.7 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3450 PF11932.8 RLN89971.1 - 0.041 13.2 4.3 0.053 12.8 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4064 PF13273.6 RLN89971.1 - 0.046 14.0 0.0 0.071 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) 2TM PF13239.6 RLN89971.1 - 0.052 13.8 1.1 0.067 13.5 0.0 1.7 2 0 0 2 2 2 0 2TM domain DUF3526 PF12040.8 RLN89972.1 - 0.0085 16.6 0.6 0.012 16.1 0.5 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3526) LPD7 PF18821.1 RLN89972.1 - 0.042 14.0 0.3 0.057 13.5 0.3 1.2 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 7 PilX_N PF14341.6 RLN89972.1 - 0.14 12.1 0.7 0.28 11.2 0.7 1.5 1 0 0 1 1 1 0 PilX N-terminal EI24 PF07264.11 RLN89973.1 - 1.8e-22 80.5 7.2 1.9e-22 80.3 7.2 1.0 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) RSN1_7TM PF02714.15 RLN89976.1 - 3e-10 39.9 6.5 3e-10 39.9 6.5 1.5 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate DUF4149 PF13664.6 RLN89976.1 - 0.15 12.4 8.4 0.27 11.6 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) TSLP PF15216.6 RLN89977.1 - 0.02 15.1 1.9 0.29 11.4 2.0 2.3 2 0 0 2 2 2 0 Thymic stromal lymphopoietin DUF1744 PF08490.12 RLN89977.1 - 0.087 11.4 0.0 0.17 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) DUF2969 PF11184.8 RLN89977.1 - 0.11 12.9 0.1 0.28 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2969) GIT_CC PF16559.5 RLN89977.1 - 0.21 11.5 5.9 0.33 10.8 0.3 3.2 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor ADH_zinc_N_2 PF13602.6 RLN89979.1 - 1.4e-17 64.9 0.1 2.4e-17 64.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 RLN89979.1 - 3.4e-14 52.9 0.3 3.5e-13 49.7 0.1 2.3 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN89979.1 - 1.9e-07 31.0 0.1 1.6e-06 27.9 0.0 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 RLN89979.1 - 0.0025 17.2 1.1 0.0071 15.7 1.0 1.9 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_16 PF10294.9 RLN89979.1 - 0.0069 16.1 0.1 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Glyco_hydro_6 PF01341.17 RLN89980.1 - 2e-08 34.3 0.0 2.3e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 WW PF00397.26 RLN89981.1 - 1e-06 28.7 1.7 2.8e-06 27.3 1.7 1.8 1 0 0 1 1 1 1 WW domain DUF3974 PF13120.6 RLN89981.1 - 0.2 11.8 1.3 0.64 10.1 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) WD40 PF00400.32 RLN89982.1 - 1.3e-06 29.0 1.1 0.51 11.3 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN89982.1 - 0.00054 20.2 0.0 0.1 12.9 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3155 PF11352.8 RLN89983.1 - 1 9.8 4.7 19 5.7 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3155) LRR_6 PF13516.6 RLN89986.1 - 7.9e-08 31.8 8.2 0.066 13.3 0.1 5.6 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 RLN89986.1 - 1.6e-07 30.9 0.3 0.13 12.9 0.1 5.9 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.6 RLN89986.1 - 2.5e-07 30.4 0.9 0.037 13.8 0.0 4.2 2 2 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 RLN89986.1 - 3.2e-05 24.2 5.4 1 9.9 0.2 5.1 4 2 0 4 4 4 2 Leucine Rich repeats (2 copies) GNAT_like PF18407.1 RLN89986.1 - 0.066 13.6 0.3 0.34 11.3 0.0 2.5 2 0 0 2 2 2 0 GCN5-related N-acetyltransferase like domain YHYH PF14240.6 RLN89987.1 - 1.2e-25 90.6 1.1 3.2e-13 50.1 0.0 4.7 2 2 2 4 4 4 4 YHYH protein Rad4 PF03835.15 RLN89988.1 - 0.041 13.6 1.1 5.5 6.7 0.2 2.6 2 0 0 2 2 2 0 Rad4 transglutaminase-like domain Sirohm_synth_M PF14824.6 RLN89988.1 - 0.64 9.5 6.7 5 6.7 1.0 2.7 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central Pkinase PF00069.25 RLN89989.1 - 5.6e-46 157.0 0.0 9.1e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89989.1 - 1.1e-44 152.6 0.0 1.7e-44 152.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RLN89989.1 - 0.1 11.5 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 RLN89990.1 - 3.7e-48 164.2 0.0 5.9e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89990.1 - 8.5e-45 153.1 0.0 1.1e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Podoplanin PF05808.11 RLN89990.1 - 1.7e-06 28.3 12.4 4.8e-06 26.8 12.4 1.9 1 0 0 1 1 1 1 Podoplanin PTP_tm PF18861.1 RLN89990.1 - 0.0013 18.8 0.1 0.0021 18.1 0.1 1.3 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J VSP PF03302.13 RLN89990.1 - 0.0023 16.9 21.4 0.0023 16.9 21.4 2.0 1 1 1 2 2 2 1 Giardia variant-specific surface protein CD34_antigen PF06365.12 RLN89990.1 - 0.09 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family SPX PF03105.19 RLN89990.1 - 0.12 12.2 2.7 0.17 11.8 2.7 1.2 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 RLN89990.1 - 0.2 10.8 7.8 0.27 10.4 7.8 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 RLN89990.1 - 0.78 8.5 5.1 1 8.1 5.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Plasmodium_Vir PF05795.11 RLN89990.1 - 0.91 8.9 2.5 1.3 8.4 2.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PsbX PF06596.11 RLN89990.1 - 4.7 7.3 6.7 9.6 6.3 6.7 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) FixS PF03597.15 RLN89990.1 - 4.9 6.9 4.6 9.2 6.1 4.6 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type DUF1180 PF06679.12 RLN89990.1 - 5.4 7.4 8.5 15 6.0 8.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Macoilin PF09726.9 RLN89990.1 - 6.7 5.1 6.4 9.9 4.6 6.4 1.3 1 0 0 1 1 1 0 Macoilin family Trehalase PF01204.18 RLN89992.1 - 1.4e-134 449.8 0.0 1.6e-134 449.6 0.0 1.0 1 0 0 1 1 1 1 Trehalase Glyco_hydro_63 PF03200.16 RLN89992.1 - 0.007 15.2 0.2 0.85 8.3 0.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain DUF4148 PF13663.6 RLN89992.1 - 0.55 10.5 2.2 0.67 10.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Pkinase PF00069.25 RLN89994.1 - 1.7e-47 162.0 0.0 2.5e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN89994.1 - 8e-44 149.9 0.0 1.2e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Cupin_6 PF12852.7 RLN89994.1 - 0.042 13.6 0.3 0.085 12.6 0.3 1.5 1 0 0 1 1 1 0 Cupin Serglycin PF04360.12 RLN89994.1 - 1.2 9.0 4.3 1.7 8.6 2.9 1.8 2 0 0 2 2 2 0 Serglycin Y_phosphatase2 PF03162.13 RLN89995.1 - 4.9e-22 78.3 0.2 1.2e-11 44.4 0.0 2.0 1 1 1 2 2 2 2 Tyrosine phosphatase family NADH_4Fe-4S PF10589.9 RLN89996.1 - 3.8e-10 39.7 0.0 4.9e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region HECT_2 PF09814.9 RLN89997.1 - 0.033 13.1 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Fez1 PF06818.15 RLN89998.1 - 0.04 14.4 5.0 0.033 14.6 3.3 1.7 2 0 0 2 2 2 0 Fez1 SNARE PF05739.19 RLN89998.1 - 0.16 12.0 0.1 17 5.5 0.0 2.6 2 0 0 2 2 2 0 SNARE domain DUF3584 PF12128.8 RLN89999.1 - 4.6 4.6 25.3 7 4.0 25.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Pkinase PF00069.25 RLN90000.1 - 1.5e-15 57.3 0.0 1.7e-15 57.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90000.1 - 1.5e-11 44.1 0.0 1.6e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase ZapB PF06005.12 RLN90002.1 - 0.011 16.2 2.7 3.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Cell division protein ZapB CC2-LZ PF16516.5 RLN90002.1 - 0.012 15.9 0.5 0.14 12.5 0.0 2.2 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Bap31_Bap29_C PF18035.1 RLN90002.1 - 0.021 14.8 0.3 0.021 14.8 0.3 1.9 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Spectrin_like PF18373.1 RLN90002.1 - 0.044 13.8 1.3 0.16 12.1 0.7 2.1 2 0 0 2 2 2 0 Spectrin like domain Mito_fiss_reg PF05308.11 RLN90002.1 - 0.05 13.7 0.7 0.066 13.3 0.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF5372 PF17342.2 RLN90002.1 - 0.088 13.2 0.1 0.99 9.9 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5372) DASH_Spc34 PF08657.10 RLN90002.1 - 0.094 12.5 0.5 0.13 12.0 0.5 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 DUF2333 PF10095.9 RLN90002.1 - 0.11 11.4 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) Csm1_N PF18504.1 RLN90002.1 - 0.38 11.1 3.0 13 6.2 1.4 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain Spc7 PF08317.11 RLN90002.1 - 0.49 9.2 4.4 0.11 11.4 1.2 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein Zip PF02535.22 RLN90003.1 - 0.00011 21.5 1.4 0.00014 21.2 1.4 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4834 PF16118.5 RLN90003.1 - 0.033 15.1 4.8 0.033 15.1 4.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) Neur_chan_memb PF02932.16 RLN90003.1 - 0.039 14.0 0.2 0.053 13.6 0.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF789 PF05623.12 RLN90003.1 - 1.3 8.7 8.1 2.7 7.6 8.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF789) V_ATPase_I PF01496.19 RLN90003.1 - 1.9 6.3 5.4 2.7 5.8 5.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hid1 PF12722.7 RLN90003.1 - 5.1 5.1 8.3 6.1 4.8 8.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-C3HC4_3 PF13920.6 RLN90004.1 - 2.3e-09 37.0 12.8 4.2e-09 36.1 12.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN90004.1 - 9.9e-09 35.4 13.3 1.8e-08 34.5 13.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN90004.1 - 5.5e-08 32.5 14.6 9.7e-08 31.7 14.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN90004.1 - 1.1e-07 31.6 13.0 2.3e-07 30.5 13.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 RLN90004.1 - 1.3e-06 28.2 13.8 2.3e-06 27.3 13.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN90004.1 - 7.8e-06 25.8 11.7 1.5e-05 24.8 11.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RLN90004.1 - 8.4e-05 22.5 6.8 8.4e-05 22.5 6.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 RLN90004.1 - 0.00025 21.3 12.7 0.00057 20.1 12.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 RLN90004.1 - 0.0012 18.9 9.3 0.0043 17.2 9.4 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 RLN90004.1 - 0.003 17.3 10.3 0.0062 16.3 10.3 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 RLN90004.1 - 0.021 14.9 7.8 0.041 13.9 7.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 RLN90004.1 - 0.11 12.2 11.1 0.19 11.4 11.1 1.3 1 0 0 1 1 1 0 P-11 zinc finger HypA PF01155.19 RLN90004.1 - 0.18 11.8 5.4 0.39 10.7 5.4 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA IBR PF01485.21 RLN90004.1 - 0.92 9.8 14.2 0.2 11.9 9.6 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_11 PF17123.5 RLN90004.1 - 2.4 8.0 11.8 0.61 9.9 6.2 2.5 2 0 0 2 2 2 0 RING-like zinc finger Carboxyl_trans PF01039.22 RLN90005.1 - 8.6e-153 509.5 0.0 1.1e-152 509.2 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Nop14 PF04147.12 RLN90006.1 - 7.3 4.7 12.2 11 4.1 12.2 1.2 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 RLN90007.1 - 4.1e-30 105.0 0.0 5.8e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90007.1 - 1.8e-14 53.6 0.0 2.9e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN90007.1 - 0.079 12.3 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like UDPGT PF00201.18 RLN90008.1 - 1.1e-22 80.5 0.0 1.3e-17 63.8 0.0 2.0 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 RLN90008.1 - 9.8e-05 22.4 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain SPT2 PF08243.11 RLN90009.1 - 1.2e-13 51.6 10.8 2.8e-13 50.3 10.8 1.7 1 0 0 1 1 1 1 SPT2 chromatin protein Med26 PF08711.11 RLN90009.1 - 1.5e-09 37.8 0.9 3e-09 36.8 0.9 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain SAM_1 PF00536.30 RLN90009.1 - 1.2e-07 32.1 0.0 2.3e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RLN90009.1 - 5.6e-05 23.2 0.1 0.00015 21.8 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) EF-hand_1 PF00036.32 RLN90010.1 - 3.4e-20 70.0 3.1 0.00018 20.8 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 RLN90010.1 - 1.5e-18 65.1 7.4 0.00013 21.6 0.1 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 RLN90010.1 - 3.2e-18 65.9 1.9 1.3e-08 35.2 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RLN90010.1 - 5.4e-16 58.2 0.5 0.001 18.9 0.1 4.4 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 RLN90010.1 - 9.1e-14 50.2 0.6 0.00047 19.5 0.0 4.8 4 0 0 4 4 4 2 EF hand EF-hand_10 PF14788.6 RLN90010.1 - 0.25 11.2 0.9 5.8 6.9 0.1 2.9 2 1 1 3 3 3 0 EF hand Peptidase_M22 PF00814.25 RLN90011.1 - 4.3e-39 134.8 0.1 4.5e-19 69.2 0.0 2.0 1 1 1 2 2 2 2 Glycoprotease family Peptidase_C69 PF03577.15 RLN90012.1 - 5.4e-44 150.7 0.1 8.4e-44 150.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase family C69 DUF4440 PF14534.6 RLN90012.1 - 0.011 16.1 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Ank_5 PF13857.6 RLN90013.1 - 5.7e-16 58.4 1.9 0.00029 21.1 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN90013.1 - 6.2e-16 58.0 2.7 0.00014 22.1 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 RLN90013.1 - 2.4e-14 53.7 0.1 4.1e-10 40.1 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN90013.1 - 7e-13 48.8 0.5 1.9e-05 25.1 0.1 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN90013.1 - 2e-12 46.1 1.3 4.7e-05 23.5 0.0 5.2 4 1 0 4 4 4 3 Ankyrin repeat FYVE PF01363.21 RLN90013.1 - 0.01 16.0 7.8 0.038 14.1 7.7 2.0 1 1 0 1 1 1 0 FYVE zinc finger IBR PF01485.21 RLN90013.1 - 0.027 14.7 3.2 0.027 14.7 3.2 1.8 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Pkinase PF00069.25 RLN90014.1 - 6e-22 78.3 1.0 2.9e-21 76.0 0.1 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90014.1 - 4.1e-13 49.2 0.1 6.7e-13 48.5 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN90014.1 - 0.032 13.6 0.1 3.8 6.7 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Peptidase_C97 PF05903.14 RLN90015.1 - 1.6e-26 93.0 0.0 2.9e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 RLN90015.1 - 5.3e-11 42.3 1.1 9.7e-11 41.4 1.1 1.3 1 0 0 1 1 1 1 PUL domain EF-hand_7 PF13499.6 RLN90015.1 - 2.4e-07 31.1 0.0 0.025 15.0 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair Myb_DNA-bind_4 PF13837.6 RLN90015.1 - 9.5e-07 29.1 0.2 2e-06 28.1 0.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain HU-CCDC81_euk_1 PF14908.6 RLN90015.1 - 9.7e-07 28.9 0.0 2.7e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_euk_2 PF18289.1 RLN90015.1 - 0.00025 21.1 0.0 0.01 16.0 0.0 2.5 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 2 EF-hand_8 PF13833.6 RLN90015.1 - 0.00027 20.7 0.0 0.0088 15.9 0.0 3.2 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN90015.1 - 0.0033 17.3 0.1 2.8 8.1 0.0 3.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 RLN90015.1 - 0.019 14.5 0.0 0.56 9.9 0.0 3.3 4 0 0 4 4 4 0 EF hand MADF_DNA_bdg PF10545.9 RLN90015.1 - 0.032 14.5 0.5 0.17 12.2 0.1 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like IQ PF00612.27 RLN90015.1 - 0.1 12.5 1.4 0.31 11.0 1.4 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif Bac_DNA_binding PF00216.21 RLN90015.1 - 0.11 12.7 0.1 0.28 11.4 0.1 1.6 1 0 0 1 1 1 0 Bacterial DNA-binding protein Esterase PF00756.20 RLN90016.1 - 1.2e-33 116.8 0.0 1.7e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 RLN90016.1 - 0.046 13.0 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LCAT PF02450.15 RLN90017.1 - 1.6e-57 195.5 0.1 6e-56 190.3 0.0 2.3 2 1 0 2 2 2 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 RLN90017.1 - 0.04 13.4 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF900 PF05990.12 RLN90017.1 - 0.078 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) SpoU_methylase PF00588.19 RLN90018.1 - 4.4e-10 39.9 0.0 1.2e-07 32.0 0.0 2.2 1 1 1 2 2 2 2 SpoU rRNA Methylase family Peptidase_S8 PF00082.22 RLN90019.1 - 2.2e-33 115.8 0.0 6e-33 114.4 0.0 1.6 1 1 0 1 1 1 1 Subtilase family UPF0176_N PF17773.1 RLN90020.1 - 7.4e-17 61.5 0.0 1.5e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Peptidase_M48 PF01435.18 RLN90020.1 - 2.7e-09 37.1 0.0 5.1e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 Rhodanese PF00581.20 RLN90020.1 - 3.5e-05 24.3 0.0 8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese_C PF12368.8 RLN90020.1 - 0.00028 21.2 0.1 0.00058 20.2 0.1 1.5 1 0 0 1 1 1 1 Rhodanase C-terminal DUF2430 PF10353.9 RLN90020.1 - 0.0025 18.2 0.0 0.0051 17.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2430) Ala_racemase_N PF01168.20 RLN90021.1 - 5.9e-20 71.8 0.4 6.9e-20 71.6 0.4 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ank_4 PF13637.6 RLN90022.1 - 2.7e-39 133.1 1.6 2e-08 34.6 0.0 5.2 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN90022.1 - 4.7e-37 126.4 1.4 3.1e-12 46.9 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN90022.1 - 4.2e-25 87.5 5.9 7.1e-07 29.4 0.0 6.1 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 RLN90022.1 - 7.7e-25 86.2 3.6 8.4e-05 22.9 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 RLN90022.1 - 3e-23 79.4 2.3 0.025 15.1 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat Pkinase_Tyr PF07714.17 RLN90022.1 - 1.1e-09 38.0 0.0 2.2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN90022.1 - 1.2e-06 28.1 0.0 2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF4214 PF13946.6 RLN90022.1 - 0.03 14.4 0.4 0.074 13.1 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) FliJ PF02050.16 RLN90022.1 - 0.38 11.0 7.0 1.5 9.0 4.9 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein Sugar_tr PF00083.24 RLN90023.1 - 6.6e-77 259.3 12.8 7.4e-77 259.1 12.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN90023.1 - 1.1e-14 54.2 25.5 6.9e-14 51.5 16.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2583 PF10762.9 RLN90023.1 - 0.38 11.2 6.2 0.8 10.2 5.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) DUF4084 PF13321.6 RLN90023.1 - 0.45 10.0 9.1 0.67 9.5 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4084) CytB6-F_Fe-S PF08802.10 RLN90023.1 - 0.74 9.9 9.2 2.6 8.2 0.4 3.2 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit Gal4_dimer PF03902.13 RLN90024.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Gal4-like dimerisation domain ER PF01133.17 RLN90025.1 - 2.9e-37 126.6 0.6 5.2e-37 125.8 0.6 1.4 1 1 0 1 1 1 1 Enhancer of rudimentary Skp1_POZ PF03931.15 RLN90026.1 - 0.00073 19.7 0.0 0.0022 18.1 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.31 RLN90026.1 - 0.0031 17.7 0.0 0.0038 17.4 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain PepSY_like PF11396.8 RLN90026.1 - 0.078 13.5 0.0 0.092 13.3 0.0 1.1 1 0 0 1 1 1 0 Putative beta-lactamase-inhibitor-like, PepSY-like TssN PF17555.2 RLN90027.1 - 7.4 5.9 10.7 0.39 10.1 1.1 2.5 1 1 1 2 2 2 0 Type VI secretion system, TssN DUF1084 PF06454.11 RLN90028.1 - 6.8e-08 32.2 35.7 0.0014 18.1 2.5 5.4 5 0 0 5 5 5 4 Protein of unknown function (DUF1084) Seipin PF06775.14 RLN90028.1 - 0.0029 17.7 4.3 0.74 9.9 0.0 4.1 4 0 0 4 4 4 2 Putative adipose-regulatory protein (Seipin) Spermine_synt_N PF17284.2 RLN90028.1 - 0.0094 15.8 0.1 31 4.6 0.0 4.4 5 0 0 5 5 5 1 Spermidine synthase tetramerisation domain CholecysA-Rec_N PF09193.10 RLN90028.1 - 0.019 15.0 7.0 27 4.9 0.2 4.8 4 0 0 4 4 4 0 Cholecystokinin A receptor, N-terminal DUF416 PF04222.12 RLN90028.1 - 0.028 13.8 0.4 3 7.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF416) Ras PF00071.22 RLN90029.1 - 4.3e-17 62.2 0.1 3.9e-16 59.1 0.1 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RLN90029.1 - 7.9e-08 32.5 0.0 1.1e-07 32.1 0.0 1.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 RLN90029.1 - 0.0014 18.7 0.1 0.0016 18.5 0.1 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 RLN90029.1 - 0.022 14.5 0.0 0.031 14.0 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 RLN90029.1 - 0.058 12.9 0.2 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B Gtr1_RagA PF04670.12 RLN90029.1 - 0.12 11.7 0.1 0.21 10.9 0.0 1.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region UL41A PF17591.2 RLN90030.1 - 0.22 11.6 2.0 1.6 8.9 0.1 2.7 2 1 0 2 2 2 0 Herpesvirus UL41A DUF2964 PF11177.8 RLN90030.1 - 0.41 10.9 3.3 0.62 10.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2964) Strabismus PF06638.11 RLN90030.1 - 3.7 6.1 6.5 1.4 7.5 1.3 2.1 2 0 0 2 2 2 0 Strabismus protein ABC_transp_aux PF09822.9 RLN90031.1 - 1.9e-05 24.3 0.0 2.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DDOST_48kD PF03345.14 RLN90031.1 - 0.00078 18.4 0.0 0.0038 16.1 0.0 1.9 2 0 0 2 2 2 1 Oligosaccharyltransferase 48 kDa subunit beta DUF4686 PF15742.5 RLN90031.1 - 0.14 11.3 0.1 0.21 10.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) VP4_helical PF17478.2 RLN90032.1 - 0.0064 16.0 0.0 0.0076 15.7 0.0 1.0 1 0 0 1 1 1 1 Rotavirus VP4 helical domain Cob_adeno_trans PF01923.18 RLN90032.1 - 0.017 15.3 0.1 0.021 14.9 0.1 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase HIRAN PF08797.11 RLN90032.1 - 0.018 15.0 0.0 0.044 13.7 0.0 1.7 1 1 0 1 1 1 0 HIRAN domain NTF2 PF02136.20 RLN90033.1 - 2.3e-16 60.4 0.1 2.8e-16 60.2 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain FSH1 PF03959.13 RLN90034.1 - 7.2e-22 78.1 0.0 4.5e-20 72.2 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 RLN90034.1 - 0.012 15.4 0.1 0.024 14.5 0.1 1.4 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase TBP PF00352.21 RLN90035.1 - 7.6e-49 163.6 0.0 6.9e-28 96.4 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DEAD PF00270.29 RLN90036.1 - 2.5e-36 125.1 0.9 4e-36 124.4 0.9 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN90036.1 - 1.8e-28 99.1 0.2 4.1e-27 94.7 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN90036.1 - 1.2e-07 31.8 0.2 2.6e-07 30.8 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HEM4 PF02602.15 RLN90036.1 - 0.022 14.1 0.4 0.071 12.4 0.0 2.0 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD UTP25 PF06862.12 RLN90036.1 - 0.022 13.6 0.3 0.33 9.7 0.0 2.3 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 T4SS-DNA_transf PF02534.14 RLN90036.1 - 0.13 11.1 0.0 0.24 10.1 0.0 1.4 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer EF-hand_7 PF13499.6 RLN90037.1 - 0.0016 18.9 0.0 0.0025 18.2 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN90037.1 - 0.0044 16.8 0.0 0.015 15.2 0.0 1.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 RLN90037.1 - 0.011 15.2 0.1 0.096 12.3 0.0 2.1 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 RLN90037.1 - 0.013 14.9 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 EF hand KIX_2 PF16987.5 RLN90038.1 - 1.9e-06 27.8 0.0 1.9e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 KIX domain KIX PF02172.16 RLN90038.1 - 0.0017 18.6 0.0 0.0031 17.7 0.0 1.4 1 0 0 1 1 1 1 KIX domain Pkinase_Tyr PF07714.17 RLN90039.1 - 3.4e-36 124.8 0.0 3.9e-36 124.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN90039.1 - 1.5e-32 113.0 0.0 1.9e-32 112.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 RLN90039.1 - 0.019 14.9 0.2 0.037 13.9 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN90039.1 - 0.17 10.8 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain MafB19-deam PF14437.6 RLN90040.1 - 1.5e-06 28.0 0.0 3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 RLN90040.1 - 3.8e-06 26.7 0.1 8.7e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 RLN90040.1 - 0.063 13.4 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase Fibrillarin PF01269.17 RLN90041.1 - 3e-28 98.5 0.0 3.3e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin Glyco_transf_7C PF02709.14 RLN90042.1 - 2.5e-23 81.5 0.1 5.5e-23 80.4 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 RLN90042.1 - 9.1e-13 48.0 0.0 2.1e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.9 RLN90042.1 - 0.00015 21.3 0.0 0.0016 18.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 CHGN PF05679.16 RLN90042.1 - 0.031 13.1 0.0 0.076 11.8 0.0 1.6 2 0 0 2 2 2 0 Chondroitin N-acetylgalactosaminyltransferase RIX1 PF08167.12 RLN90043.1 - 0.0023 17.7 2.8 0.004 16.9 1.8 2.0 1 1 0 1 1 1 1 rRNA processing/ribosome biogenesis Cnd1 PF12717.7 RLN90043.1 - 0.0076 16.3 0.1 0.72 9.9 0.0 3.0 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RLN90043.1 - 0.018 15.4 6.0 0.16 12.4 0.4 4.2 3 2 0 4 4 4 0 HEAT repeats HEAT_EZ PF13513.6 RLN90043.1 - 0.16 12.5 5.7 0.45 11.1 0.0 4.0 4 1 0 4 4 4 0 HEAT-like repeat Arm PF00514.23 RLN90043.1 - 0.62 10.2 0.0 0.62 10.2 0.0 3.9 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN90043.1 - 0.98 9.8 7.6 1 9.8 0.2 4.2 4 0 0 4 4 4 0 HEAT repeat RCC1 PF00415.18 RLN90046.1 - 4.8e-74 244.8 13.3 1.5e-16 60.7 0.0 6.1 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN90046.1 - 2.3e-33 113.3 26.4 4.6e-08 32.7 0.0 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 RLN90046.1 - 1.2e-05 25.5 0.1 2.6e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain 2-oxoacid_dh PF00198.23 RLN90047.1 - 3.9e-67 226.1 0.0 5.9e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 RLN90047.1 - 2.3e-20 72.2 0.6 3.9e-20 71.4 0.6 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 RLN90047.1 - 6.4e-15 55.2 2.2 9.6e-15 54.6 0.0 2.5 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 RLN90047.1 - 0.0073 16.1 2.6 0.16 11.8 0.4 2.6 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_D23 PF16576.5 RLN90047.1 - 0.06 12.5 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion FGGY_C PF02782.16 RLN90048.1 - 6.7e-22 78.2 0.3 3.1e-21 76.0 0.1 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 RLN90048.1 - 1.5e-21 77.1 0.0 3.3e-12 46.5 0.0 2.3 1 1 1 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain DUF1218 PF06749.12 RLN90049.1 - 0.86 10.2 6.4 0.25 11.9 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) CCG PF02754.16 RLN90050.1 - 0.033 14.4 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 Cysteine-rich domain Transposase_mut PF00872.18 RLN90050.1 - 0.077 11.8 0.0 0.091 11.6 0.0 1.0 1 0 0 1 1 1 0 Transposase, Mutator family PIP5K PF01504.18 RLN90051.1 - 6.4e-64 215.8 0.0 2.9e-63 213.7 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7TM_GPCR_Srsx PF10320.9 RLN90051.1 - 1.8e-05 24.3 3.5 3.1e-05 23.5 3.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Clat_adaptor_s PF01217.20 RLN90051.1 - 0.0011 18.9 0.1 0.0025 17.8 0.1 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DoxX_2 PF13564.6 RLN90051.1 - 0.016 15.3 0.0 0.043 13.9 0.0 1.7 1 0 0 1 1 1 0 DoxX-like family DUF3278 PF11683.8 RLN90051.1 - 0.076 13.1 1.3 0.2 11.7 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) 7tm_2 PF00002.24 RLN90051.1 - 0.13 11.5 7.9 0.015 14.6 2.6 1.9 1 1 1 2 2 2 0 7 transmembrane receptor (Secretin family) DUF1516 PF07457.11 RLN90051.1 - 6.7 7.0 9.1 0.085 13.1 1.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1516) EF-hand_7 PF13499.6 RLN90053.1 - 4.5e-11 43.0 0.7 3.7e-06 27.3 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN90053.1 - 2.4e-08 32.9 3.6 0.0068 15.9 0.1 3.9 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 RLN90053.1 - 1.3e-05 24.8 4.4 0.014 15.3 0.1 3.7 4 0 0 4 4 4 1 EF-hand domain EF-hand_9 PF14658.6 RLN90053.1 - 6.9e-05 23.1 0.1 0.00053 20.3 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 RLN90053.1 - 0.043 13.7 2.4 0.51 10.2 0.1 3.2 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.6 RLN90053.1 - 0.058 12.9 2.2 4.8 6.9 0.1 2.8 2 0 0 2 2 2 0 EF hand DEC-1_N PF04625.13 RLN90053.1 - 8.9 5.2 9.0 9 5.2 7.8 1.6 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Biotin_lipoyl PF00364.22 RLN90054.1 - 7.4e-14 51.3 0.3 1.2e-13 50.7 0.3 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 RLN90054.1 - 0.1 13.3 0.0 2.6 8.8 0.0 2.3 1 1 1 2 2 2 0 HlyD family secretion protein DUF3584 PF12128.8 RLN90055.1 - 0.83 7.1 45.8 1.5 6.3 45.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RYDR_ITPR PF01365.21 RLN90056.1 - 3.4e-11 43.0 0.0 1.5e-10 40.9 0.0 2.0 1 1 0 1 1 1 1 RIH domain Ins145_P3_rec PF08709.11 RLN90057.1 - 2.4e-06 26.9 0.1 0.00022 20.5 0.0 3.0 2 1 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor LTV PF04180.14 RLN90058.1 - 1.4e-14 54.6 48.3 8.4e-13 48.8 20.9 3.9 1 1 2 3 3 3 2 Low temperature viability protein PorA PF11271.8 RLN90058.1 - 0.082 12.2 5.0 0.19 11.0 5.0 1.6 1 0 0 1 1 1 0 Porin PorA HSF_DNA-bind PF00447.17 RLN90059.1 - 4.1e-24 85.0 0.1 6.4e-24 84.4 0.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Phage_int_SAM_4 PF13495.6 RLN90060.1 - 0.15 12.5 0.0 0.6 10.6 0.0 1.9 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Trypsin PF00089.26 RLN90061.1 - 1.6e-53 181.8 2.0 2.4e-53 181.2 2.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 RLN90061.1 - 1e-06 29.7 0.4 3.7e-06 27.9 0.4 1.9 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_M3 PF01432.20 RLN90062.1 - 1.1e-130 437.0 0.0 3.3e-90 303.6 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M3 Peptidase_M50B PF13398.6 RLN90062.1 - 0.039 13.6 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Trypsin PF00089.26 RLN90063.1 - 1.1e-53 182.3 2.5 2.8e-53 181.0 2.5 1.6 1 0 0 1 1 1 1 Trypsin TFIIA PF03153.13 RLN90063.1 - 0.52 10.3 53.1 0.94 9.4 53.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_UL51 PF04540.13 RLN90064.1 - 0.11 12.3 0.1 9.8 5.9 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus UL51 protein SPRY PF00622.28 RLN90065.1 - 1.4e-07 31.6 0.2 2.2e-07 31.0 0.2 1.3 1 0 0 1 1 1 1 SPRY domain F-box PF00646.33 RLN90065.1 - 0.00047 20.0 0.1 0.0011 18.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 RLN90065.1 - 0.0024 17.7 0.9 0.0057 16.5 0.1 2.0 1 1 1 2 2 2 1 F-box-like Solute_trans_a PF03619.16 RLN90066.1 - 6.4e-82 275.0 9.9 8.3e-82 274.7 9.9 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Nucleoporin_FG PF13634.6 RLN90068.1 - 0.00063 20.5 0.0 0.0013 19.6 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin FG repeat region VIR_N PF15912.5 RLN90069.1 - 1.9 8.0 3.6 7 6.2 0.9 2.3 2 0 0 2 2 2 0 Virilizer, N-terminal PDT PF00800.18 RLN90070.1 - 3.4e-16 59.6 1.0 6.2e-16 58.7 1.0 1.4 1 0 0 1 1 1 1 Prephenate dehydratase UPRTase PF14681.6 RLN90071.1 - 1.2e-46 158.8 0.9 2.5e-45 154.5 0.9 2.0 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 RLN90071.1 - 0.084 12.4 0.1 0.095 12.2 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain RT_RNaseH_2 PF17919.1 RLN90071.1 - 0.091 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase PH PF00169.29 RLN90072.1 - 8.8e-62 206.2 17.8 2.3e-11 44.1 0.0 9.5 7 4 0 7 7 7 7 PH domain PH_11 PF15413.6 RLN90072.1 - 1.2e-34 118.9 28.3 3.4e-07 30.6 1.2 9.8 8 3 1 10 10 10 7 Pleckstrin homology domain PH_8 PF15409.6 RLN90072.1 - 3.5e-34 117.0 8.3 1.7e-06 28.2 0.2 7.5 7 1 0 7 7 7 6 Pleckstrin homology domain PH_9 PF15410.6 RLN90072.1 - 4.1e-06 27.1 3.0 11 6.4 0.0 7.9 7 2 2 9 9 9 1 Pleckstrin homology domain PH_4 PF15404.6 RLN90072.1 - 0.035 13.9 1.0 0.88 9.3 0.0 3.6 6 0 0 6 6 6 0 Pleckstrin homology domain BCL_N PF04714.13 RLN90072.1 - 6.3 6.9 6.4 4.9 7.3 0.1 3.9 5 0 0 5 5 5 0 BCL7, N-terminal conserver region Tctex-1 PF03645.13 RLN90073.1 - 3.2e-05 24.1 0.0 5.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Tctex-1 family T3SSipB PF16535.5 RLN90073.1 - 0.027 15.0 0.3 0.049 14.1 0.0 1.5 2 0 0 2 2 2 0 Type III cell invasion protein SipB Dpy-30 PF05186.13 RLN90073.1 - 0.088 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Dpy-30 motif PH PF00169.29 RLN90074.1 - 2.1e-39 134.3 0.1 2.3e-09 37.7 0.0 5.0 5 0 0 5 5 5 4 PH domain PH_11 PF15413.6 RLN90074.1 - 5.3e-17 62.2 15.5 0.00067 20.0 0.6 6.2 5 2 0 5 5 5 4 Pleckstrin homology domain PH_8 PF15409.6 RLN90074.1 - 6.4e-15 55.2 0.3 0.00059 20.1 0.0 4.5 4 0 0 4 4 4 4 Pleckstrin homology domain Tctex-1 PF03645.13 RLN90074.1 - 1.3e-06 28.5 0.2 3.6e-06 27.1 0.2 1.7 1 0 0 1 1 1 1 Tctex-1 family PH_9 PF15410.6 RLN90074.1 - 0.0016 18.8 0.2 23 5.4 0.0 4.7 4 1 0 4 4 4 1 Pleckstrin homology domain Peptidase_M18 PF02127.15 RLN90075.1 - 1.4e-167 557.9 0.0 1.6e-167 557.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 RLN90075.1 - 1.7e-07 30.5 0.3 9.3e-07 28.1 0.3 2.0 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase NADH_dh_m_C1 PF15088.6 RLN90075.1 - 0.015 14.9 0.0 0.063 12.9 0.0 1.9 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial p25-alpha PF05517.12 RLN90076.1 - 1.9e-06 28.2 0.0 3.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 p25-alpha Mcp5_PH PF12814.7 RLN90076.1 - 0.033 14.3 0.1 0.21 11.7 0.0 2.2 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology ECH_2 PF16113.5 RLN90077.1 - 6.7e-115 384.1 0.1 1.7e-114 382.8 0.1 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 RLN90077.1 - 3.8e-32 111.6 0.6 2.7e-30 105.5 0.0 3.0 3 1 1 4 4 4 2 Enoyl-CoA hydratase/isomerase Med21 PF11221.8 RLN90078.1 - 0.027 14.7 1.2 0.027 14.7 1.2 2.9 2 1 0 2 2 2 0 Subunit 21 of Mediator complex CbbQ_C PF08406.10 RLN90078.1 - 0.19 12.0 0.2 0.19 12.0 0.2 2.5 3 0 0 3 3 3 0 CbbQ/NirQ/NorQ C-terminal GreA_GreB_N PF03449.15 RLN90078.1 - 7 6.9 13.3 0.63 10.2 0.6 3.4 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal Pkinase PF00069.25 RLN90079.1 - 2.1e-57 194.5 0.0 3.4e-57 193.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 RLN90079.1 - 4.9e-40 135.5 0.4 2.2e-18 66.1 0.0 3.8 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 RLN90079.1 - 2e-28 99.4 0.0 5.1e-28 98.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RLN90079.1 - 0.036 13.0 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 RLN90079.1 - 0.1 11.9 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Dioxygenase_C PF00775.21 RLN90080.1 - 0.0002 20.9 0.1 0.00038 19.9 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_C PF00775.21 RLN90081.1 - 5.9e-05 22.6 0.1 0.00017 21.1 0.1 1.7 1 1 0 1 1 1 1 Dioxygenase TMEM51 PF15345.6 RLN90082.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Dioxygenase_C PF00775.21 RLN90083.1 - 5.8e-05 22.6 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase DHHA2 PF02833.14 RLN90084.1 - 6.7e-22 78.2 0.2 1.6e-21 77.0 0.0 1.7 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 RLN90084.1 - 6.8e-10 39.1 0.1 1.4e-09 38.1 0.1 1.4 1 0 0 1 1 1 1 DHH family DUF1084 PF06454.11 RLN90085.1 - 6.5e-07 29.0 8.6 5.5e-06 26.0 5.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1084) AA_permease_2 PF13520.6 RLN90087.1 - 1.2e-22 80.4 32.4 1.6e-22 80.0 32.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN90087.1 - 2.1e-12 46.4 22.6 3.3e-12 45.8 22.6 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3439 PF11921.8 RLN90087.1 - 0.44 10.5 6.6 33 4.5 7.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Glyco_hydro_38N PF01074.22 RLN90090.1 - 6.1e-58 196.5 1.2 6.1e-58 196.5 1.2 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 38 N-terminal domain Aminotran_1_2 PF00155.21 RLN90092.1 - 7.9e-06 25.3 0.0 1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II BUD22 PF09073.10 RLN90093.1 - 0.0071 15.7 14.6 0.0099 15.3 14.6 1.3 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.12 RLN90093.1 - 0.031 13.7 6.9 0.035 13.5 6.9 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RLN90093.1 - 0.25 9.5 11.4 0.32 9.1 11.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RLN90093.1 - 3.9 5.7 8.7 5.1 5.3 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein GAF_2 PF13185.6 RLN90094.1 - 1.2e-09 38.6 0.0 2.6e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 RLN90094.1 - 4.4e-08 33.8 0.9 2.8e-06 28.0 0.1 3.1 3 0 0 3 3 3 1 GAF domain FYVE PF01363.21 RLN90094.1 - 6.7e-06 26.2 18.3 1.8e-05 24.8 18.3 1.8 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN90094.1 - 0.23 11.7 12.7 0.087 13.0 9.6 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger PAN_1 PF00024.26 RLN90095.1 - 1.3e-18 66.8 19.1 6e-12 45.4 3.1 3.0 3 1 0 3 3 3 2 PAN domain PAN_4 PF14295.6 RLN90095.1 - 6.6e-17 61.1 10.4 6.7e-10 38.7 2.0 3.2 3 1 0 3 3 3 2 PAN domain PAN_2 PF08276.11 RLN90095.1 - 0.014 15.4 2.9 0.014 15.4 2.9 3.9 4 0 0 4 4 4 0 PAN-like domain PAN_1 PF00024.26 RLN90096.1 - 2.3e-13 49.9 1.9 4.2e-13 49.0 1.9 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 RLN90096.1 - 5.2e-10 39.1 2.4 5.2e-10 39.1 2.4 2.4 2 1 0 2 2 2 1 PAN domain PAN_2 PF08276.11 RLN90096.1 - 0.0073 16.4 3.2 0.0073 16.4 3.2 2.0 2 0 0 2 2 2 1 PAN-like domain UCR_Fe-S_N PF10399.9 RLN90096.1 - 1.3 8.4 4.2 12 5.3 0.0 2.2 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Na_Ca_ex PF01699.24 RLN90099.1 - 4.2e-49 166.4 39.8 1.4e-28 99.8 16.1 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF5493 PF17597.2 RLN90099.1 - 0.11 12.8 4.3 0.088 13.1 1.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5493) CCD48 PF15799.5 RLN90100.1 - 0.17 10.1 9.4 0.088 11.1 7.6 1.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 48 PIN_6 PF17146.4 RLN90100.1 - 0.21 12.1 0.9 0.56 10.7 0.1 1.9 2 0 0 2 2 2 0 PIN domain of ribonuclease SlyX PF04102.12 RLN90100.1 - 1.1 9.9 5.5 0.31 11.7 1.5 2.1 2 0 0 2 2 2 0 SlyX Ras PF00071.22 RLN90101.1 - 1.9e-50 170.6 0.1 2.4e-50 170.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN90101.1 - 6.5e-23 81.2 0.0 1.1e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN90101.1 - 3.3e-07 29.9 0.0 4.2e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RLN90101.1 - 0.0027 17.6 0.0 0.2 11.5 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase p450 PF00067.22 RLN90102.1 - 3.9e-13 49.0 0.0 4.7e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 RLN90103.1 - 1.7e-73 248.0 0.0 2e-73 247.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.7 RLN90104.1 - 1.1e-111 365.7 6.4 1.9e-16 60.4 0.0 8.5 2 1 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN90104.1 - 1e-106 348.0 27.9 6.3e-11 42.6 0.1 12.1 2 2 11 13 13 13 13 Ankyrin repeats (many copies) Ank PF00023.30 RLN90104.1 - 3.5e-93 302.3 14.2 7.9e-06 26.1 0.0 14.5 14 0 0 14 14 14 14 Ankyrin repeat Ank_3 PF13606.6 RLN90104.1 - 9.7e-91 286.7 5.8 4.8e-06 26.5 0.0 14.9 15 0 0 15 15 15 14 Ankyrin repeat Ank_5 PF13857.6 RLN90104.1 - 1.9e-75 247.9 39.0 6.6e-08 32.7 0.3 13.4 1 1 13 14 14 14 14 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 RLN90104.1 - 1.3e-17 63.9 0.0 5.5e-17 61.9 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RLN90104.1 - 4e-16 59.2 0.0 7e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain VWA_3_C PF18571.1 RLN90104.1 - 0.00063 19.6 6.8 1.1e+02 2.8 0.0 7.8 9 0 0 9 9 9 0 von Willebrand factor type A C-terminal domain YfmQ PF10787.9 RLN90104.1 - 0.0016 18.2 0.0 26 4.6 0.0 5.9 3 1 2 6 6 6 0 Uncharacterised protein from bacillus cereus group tRNA_NucTran2_2 PF13735.6 RLN90104.1 - 0.009 16.0 8.4 31 4.5 0.0 5.2 1 1 4 5 5 5 0 tRNA nucleotidyltransferase domain 2 putative SBP_bac_3 PF00497.20 RLN90104.1 - 0.015 14.7 0.3 0.77 9.1 0.0 3.3 2 1 1 3 3 3 0 Bacterial extracellular solute-binding proteins, family 3 WGG PF10273.9 RLN90104.1 - 0.027 15.1 3.3 2.7e+02 2.3 0.0 5.6 5 0 0 5 5 5 0 Pre-rRNA-processing protein TSR2 Myb_DNA-binding PF00249.31 RLN90105.1 - 1.8e-11 44.0 0.0 2.9e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN90105.1 - 0.16 12.3 0.0 0.42 10.9 0.0 1.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain F-box-like PF12937.7 RLN90106.1 - 0.0043 16.9 0.2 0.088 12.7 0.0 2.7 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 RLN90106.1 - 0.0076 16.1 0.1 1.8 8.5 0.0 2.6 2 0 0 2 2 2 2 F-box domain TPP_enzyme_N PF02776.18 RLN90106.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ABC_membrane PF00664.23 RLN90107.1 - 9.9e-55 186.1 2.7 1.3e-54 185.7 2.7 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region UPF0542 PF15086.6 RLN90107.1 - 0.12 12.3 0.1 0.32 11.0 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 CLASP_N PF12348.8 RLN90108.1 - 0.048 13.2 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 CLASP N terminal Pico_P2B PF01552.17 RLN90108.1 - 0.055 13.6 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Picornavirus 2B protein p450 PF00067.22 RLN90110.1 - 7.2e-80 269.0 0.1 9.1e-80 268.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 RLN90112.1 - 4.3e-68 230.1 0.0 5.7e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPR_1 PF00515.28 RLN90114.1 - 3.1e-20 71.1 13.1 0.0047 16.7 0.1 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 RLN90114.1 - 7.4e-15 53.8 16.0 0.041 14.0 0.3 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 RLN90114.1 - 9e-11 41.3 12.9 2.2e-06 27.2 0.6 5.1 4 1 1 5 5 5 2 TPR repeat TPR_8 PF13181.6 RLN90114.1 - 8.2e-09 35.0 10.7 0.02 15.1 0.1 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 RLN90114.1 - 1.6e-07 31.5 12.2 0.00045 20.5 0.3 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN90114.1 - 1.2e-06 28.5 5.8 0.012 15.7 0.0 4.0 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN90114.1 - 1.5e-06 28.7 15.4 0.49 11.1 0.2 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 RLN90114.1 - 2.4e-05 24.8 11.4 0.011 16.3 0.3 4.2 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN90114.1 - 0.0027 18.0 11.3 2.2 8.8 0.0 4.9 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN90114.1 - 0.03 14.3 6.5 5.1 7.4 0.1 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 RLN90114.1 - 0.057 13.5 6.7 7.1 6.8 0.0 4.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 RLN90114.1 - 0.06 13.4 1.7 7.1 6.8 0.1 3.7 3 2 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Desmo_N PF06771.11 RLN90114.1 - 0.073 13.4 0.0 0.37 11.2 0.0 2.2 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus YqaH PF17448.2 RLN90114.1 - 0.14 12.5 0.0 0.42 11.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized YqaH-like TPR_6 PF13174.6 RLN90114.1 - 0.35 11.6 13.1 4.4 8.2 0.4 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN90114.1 - 0.68 9.9 0.1 0.68 9.9 0.1 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat HHH_8 PF14716.6 RLN90114.1 - 1 9.8 3.9 0.63 10.4 0.2 2.6 3 0 0 3 3 2 0 Helix-hairpin-helix domain TPR_14 PF13428.6 RLN90114.1 - 3.4 8.7 12.8 18 6.5 0.3 4.8 3 1 2 5 5 5 0 Tetratricopeptide repeat Reprolysin_5 PF13688.6 RLN90115.1 - 0.00016 21.9 0.1 0.0028 17.8 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12 Peptidase_M6 PF05547.11 RLN90115.1 - 0.0014 17.1 2.9 0.0026 16.2 2.9 1.4 1 1 0 1 1 1 1 Immune inhibitor A peptidase M6 Reprolysin_4 PF13583.6 RLN90115.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 RLN90115.1 - 0.035 14.0 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 RLN90115.1 - 0.14 12.7 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DHBP_synthase PF00926.19 RLN90116.1 - 1.3e-80 269.5 0.0 1.9e-80 268.9 0.0 1.3 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 RLN90116.1 - 6.4e-07 29.1 0.2 0.001 18.7 0.1 3.4 2 1 0 2 2 2 1 GTP cyclohydrolase II MORN PF02493.20 RLN90116.1 - 0.071 13.0 0.4 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 MORN repeat Evr1_Alr PF04777.13 RLN90118.1 - 3.3e-18 66.0 0.4 8.5e-18 64.7 0.4 1.7 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.20 RLN90118.1 - 3.5e-17 62.3 0.2 7e-17 61.3 0.2 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 RLN90118.1 - 8.7e-05 22.9 0.7 0.00033 21.1 0.2 2.3 1 1 1 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 RLN90118.1 - 0.056 13.4 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_7 PF13899.6 RLN90118.1 - 0.12 12.6 0.0 0.51 10.6 0.0 2.1 1 0 0 1 1 1 0 Thioredoxin-like DpnI PF06044.12 RLN90118.1 - 0.95 9.1 3.5 0.41 10.3 0.1 2.0 3 0 0 3 3 3 0 Dam-replacing family Zn_Tnp_IS1595 PF12760.7 RLN90118.1 - 4.4 7.4 8.2 7.8 6.6 0.4 2.9 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 RLN90118.1 - 5.7 6.5 6.8 11 5.6 0.2 2.8 3 0 0 3 3 3 0 zinc-ribbon domain BORCS7 PF16088.5 RLN90119.1 - 0.094 13.0 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 SQAPI PF16845.5 RLN90120.1 - 0.012 15.9 0.1 0.21 11.9 0.1 2.4 1 1 1 2 2 2 0 Aspartic acid proteinase inhibitor Sds3 PF08598.11 RLN90121.1 - 1.7e-06 28.2 5.6 2.9e-06 27.4 5.6 1.3 1 0 0 1 1 1 1 Sds3-like KIX_2 PF16987.5 RLN90122.1 - 0.00051 20.0 0.1 0.00051 20.0 0.1 3.3 4 0 0 4 4 4 1 KIX domain eIF-5_eIF-2B PF01873.17 RLN90122.1 - 0.19 11.6 3.8 1.9 8.4 0.2 2.9 3 0 0 3 3 3 0 Domain found in IF2B/IF5 SLY PF12485.8 RLN90122.1 - 1.1 9.9 11.9 0.35 11.6 1.2 2.9 3 0 0 3 3 3 0 Lymphocyte signaling adaptor protein SAP130_C PF16014.5 RLN90122.1 - 2.6 7.0 22.6 2.5 7.1 4.5 2.2 2 0 0 2 2 2 0 Histone deacetylase complex subunit SAP130 C-terminus TGase_elicitor PF16683.5 RLN90123.1 - 4.3e-157 522.5 0.8 3e-156 519.8 0.4 1.8 1 1 1 2 2 2 2 Transglutaminase elicitor P2X_receptor PF00864.19 RLN90123.1 - 0.045 12.8 0.3 0.064 12.3 0.3 1.2 1 0 0 1 1 1 0 ATP P2X receptor DX PF01666.17 RLN90123.1 - 0.071 13.6 0.1 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 DX module adh_short PF00106.25 RLN90124.1 - 1e-14 54.5 0.3 1.6e-06 27.7 0.0 2.2 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN90124.1 - 1.3e-05 24.9 0.2 0.0017 18.0 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase OrfB_Zn_ribbon PF07282.11 RLN90125.1 - 4.2e-12 45.8 4.7 4.2e-12 45.8 4.7 1.9 2 0 0 2 2 2 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 RLN90125.1 - 0.0028 17.9 6.7 0.042 14.1 6.7 2.3 1 1 0 1 1 1 1 Probable transposase EST1 PF10374.9 RLN90125.1 - 0.034 14.8 0.1 0.059 14.0 0.1 1.4 1 0 0 1 1 1 0 Telomerase activating protein Est1 TAF1D PF15333.6 RLN90125.1 - 0.06 13.1 4.9 0.13 12.0 1.2 2.1 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D DUF1364 PF07102.12 RLN90125.1 - 4.3 7.3 7.7 0.28 11.0 0.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1364) AbbA_antirepres PF14156.6 RLN90127.1 - 0.061 13.2 0.5 1.9 8.5 0.0 2.2 2 0 0 2 2 2 0 Antirepressor AbbA zf-RING_2 PF13639.6 RLN90129.1 - 7.3e-08 32.6 14.4 1.3e-07 31.8 14.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RLN90129.1 - 1.2e-06 28.3 12.3 2e-06 27.6 12.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN90129.1 - 6.7e-06 25.9 14.5 1.2e-05 25.0 14.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN90129.1 - 1.3e-05 24.9 15.4 1.3e-05 24.9 15.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN90129.1 - 0.00015 21.7 10.9 0.00043 20.3 10.8 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 RLN90129.1 - 0.00027 21.0 10.6 0.00067 19.8 10.5 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 RLN90129.1 - 0.00041 20.3 13.2 0.0007 19.5 13.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 RLN90129.1 - 0.0027 18.0 12.5 0.0066 16.7 12.5 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 RLN90129.1 - 0.0089 16.1 10.1 0.016 15.3 10.1 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 RLN90129.1 - 0.0099 15.7 14.1 0.019 14.8 14.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 AAA_assoc_C PF09821.9 RLN90129.1 - 0.081 13.5 0.2 13 6.3 0.0 2.8 2 1 0 2 2 2 0 C-terminal AAA-associated domain U-box PF04564.15 RLN90129.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 U-box domain Cnd1 PF12717.7 RLN90130.1 - 2.8e-45 154.3 1.2 1.8e-43 148.4 0.1 3.8 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 RLN90130.1 - 0.0012 17.5 3.6 0.0016 17.1 0.1 2.9 3 1 0 3 3 3 1 Adaptin N terminal region TFIIF_alpha PF05793.12 RLN90130.1 - 0.0055 15.3 0.6 0.0086 14.7 0.6 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HEAT_2 PF13646.6 RLN90130.1 - 0.0085 16.5 0.2 0.18 12.3 0.0 3.3 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.22 RLN90130.1 - 0.064 13.5 2.2 6.6 7.3 0.2 4.5 4 0 0 4 4 4 0 HEAT repeat Cnd3 PF12719.7 RLN90130.1 - 0.48 9.6 6.3 0.13 11.4 0.5 3.0 4 1 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain Glyco_transf_20 PF00982.21 RLN90131.1 - 7.2e-117 391.0 0.0 1.8e-116 389.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 RLN90131.1 - 2.1e-41 141.6 0.0 3.5e-29 101.6 0.0 2.2 2 0 0 2 2 2 2 Trehalose-phosphatase Glycos_transf_1 PF00534.20 RLN90131.1 - 0.007 15.9 0.0 0.19 11.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 RPN1_RPN2_N PF17781.1 RLN90132.1 - 1.6e-112 375.9 0.8 2.5e-112 375.3 0.3 1.5 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 RLN90132.1 - 4.9e-23 80.3 9.7 8e-05 22.9 0.1 7.2 7 0 0 7 7 7 4 Proteasome/cyclosome repeat DUF483 PF04467.12 RLN90132.1 - 0.1 12.6 0.6 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF483) MatE PF01554.18 RLN90133.1 - 2.4e-38 131.3 35.3 2.2e-21 76.2 11.2 2.9 3 0 0 3 3 3 2 MatE MatE PF01554.18 RLN90134.1 - 2.3e-38 131.4 41.0 7.2e-20 71.3 16.7 2.3 2 0 0 2 2 2 2 MatE Peptidase_M17 PF00883.21 RLN90135.1 - 5e-86 288.8 1.2 1.1e-82 277.8 0.4 3.6 2 1 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 RLN90135.1 - 2.3e-10 40.4 0.3 1.3e-09 38.0 0.0 2.2 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain C2 PF00168.30 RLN90136.1 - 1.2e-62 208.6 1.5 3.8e-17 62.5 0.0 8.4 8 0 0 8 8 8 5 C2 domain PH PF00169.29 RLN90136.1 - 4.9e-16 59.1 0.2 4.6e-14 52.8 0.1 3.1 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 RLN90136.1 - 0.00043 20.7 2.1 0.002 18.5 0.6 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain DUF3597 PF12200.8 RLN90136.1 - 0.42 11.1 2.1 2.7 8.5 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3597) VPS28 PF03997.12 RLN90136.1 - 0.72 9.5 9.5 11 5.6 0.6 3.7 3 0 0 3 3 3 0 VPS28 protein DUF4110 PF13422.6 RLN90136.1 - 3.6 7.7 7.8 7.6 6.7 0.7 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4110) DUF4497 PF14924.6 RLN90137.1 - 5.4e-14 52.6 0.0 9.8e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4497) RrnaAD PF00398.20 RLN90139.1 - 3.3e-05 23.1 0.0 4.9e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 RLN90139.1 - 0.055 13.2 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Epimerase PF01370.21 RLN90140.1 - 2.2e-08 33.9 0.0 3e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 RLN90140.1 - 0.00018 20.8 0.0 0.00049 19.3 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain SapB_2 PF03489.17 RLN90141.1 - 4.6e-34 116.2 51.4 0.0003 20.8 0.1 13.8 13 1 1 14 14 14 10 Saposin-like type B, region 2 SapB_1 PF05184.15 RLN90141.1 - 0.00015 21.7 42.0 0.3 11.2 0.0 9.9 10 1 0 10 10 10 5 Saposin-like type B, region 1 HTH_23 PF13384.6 RLN90141.1 - 0.016 15.0 0.4 1.2e+02 2.6 0.0 5.7 7 0 0 7 7 7 0 Homeodomain-like domain DUF5572 PF17733.1 RLN90141.1 - 0.018 14.9 0.1 48 3.9 0.0 4.6 5 0 0 5 5 5 0 Family of unknown function (DUF5572) MMS19_C PF12460.8 RLN90141.1 - 0.69 9.0 1.9 2.9 6.9 0.2 2.5 2 1 1 3 3 3 0 RNAPII transcription regulator C-terminal Glutaredoxin PF00462.24 RLN90142.1 - 4.9e-15 55.5 0.0 1.2e-14 54.3 0.0 1.6 1 1 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 RLN90142.1 - 0.01 16.2 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 RLN90142.1 - 0.062 13.1 2.4 3.3 7.4 0.0 2.3 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 RLN90142.1 - 0.063 13.7 0.1 0.083 13.3 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_3 PF13192.6 RLN90142.1 - 0.079 13.0 0.0 1.9 8.6 0.0 2.2 1 1 0 1 1 1 0 Thioredoxin domain DUF3871 PF12987.7 RLN90142.1 - 0.2 10.4 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3871) SH3_2 PF07653.17 RLN90143.1 - 1.8e-09 37.2 0.0 4.9e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 RLN90143.1 - 7.8e-07 28.9 0.0 1.8e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RLN90143.1 - 0.00024 20.7 0.1 0.00061 19.3 0.0 1.7 2 0 0 2 2 2 1 SH3 domain RCC1 PF00415.18 RLN90144.1 - 7.5e-76 250.6 13.3 7.8e-15 55.2 0.0 8.3 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN90144.1 - 6.2e-47 156.5 25.6 3.5e-09 36.2 0.1 7.6 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat SIS_2 PF13580.6 RLN90144.1 - 0.053 13.5 0.5 16 5.5 0.0 3.1 4 0 0 4 4 4 0 SIS domain Hira PF07569.11 RLN90144.1 - 0.059 13.1 0.0 80 2.8 0.0 3.8 4 0 0 4 4 4 0 TUP1-like enhancer of split CLP1_P PF16575.5 RLN90145.1 - 2.9e-41 141.3 0.0 4.9e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 RLN90145.1 - 0.0018 18.8 0.0 0.0034 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RLN90145.1 - 0.0055 17.0 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 RLN90145.1 - 0.009 16.4 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 RLN90145.1 - 0.044 13.5 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 RLN90145.1 - 0.075 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family 2OG-Fe_Oxy_2 PF10014.9 RLN90145.1 - 0.093 12.5 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 2OG-Fe dioxygenase AAA_33 PF13671.6 RLN90145.1 - 0.11 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RLN90145.1 - 0.13 12.6 0.0 0.28 11.6 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 RLN90145.1 - 0.15 12.1 0.0 0.38 10.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain Retrotran_gag_3 PF14244.6 RLN90146.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF5314 PF17241.2 RLN90146.1 - 0.16 11.6 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5314) Ank_2 PF12796.7 RLN90147.1 - 2.3e-38 130.6 11.6 1.3e-16 60.9 0.5 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN90147.1 - 1.1e-29 102.4 0.7 3.2e-09 37.2 0.1 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN90147.1 - 2.8e-20 70.2 3.3 0.02 15.4 0.0 6.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 RLN90147.1 - 1.4e-19 69.9 4.6 8e-07 29.2 0.1 5.7 1 1 5 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN90147.1 - 3.3e-18 65.3 9.5 0.00026 21.3 0.1 6.4 6 0 0 6 6 6 5 Ankyrin repeat DUF1949 PF09186.11 RLN90147.1 - 0.0053 16.6 0.0 5.2 7.0 0.0 3.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1949) Ribosomal_L3 PF00297.22 RLN90148.1 - 1.1e-179 597.2 9.0 1.2e-179 597.0 9.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 MRP-L51 PF10244.9 RLN90148.1 - 0.091 13.0 1.7 2.7 8.3 0.0 2.8 2 1 1 3 3 3 0 Mitochondrial ribosomal subunit Aconitase PF00330.20 RLN90149.1 - 7.2e-142 473.6 0.0 8.4e-142 473.4 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Caudo_bapla_RBP PF08931.10 RLN90149.1 - 0.1 12.0 0.0 0.66 9.4 0.1 1.9 2 0 0 2 2 2 0 Receptor-binding protein of phage tail base-plate Siphoviridae, head Ribophorin_I PF04597.14 RLN90150.1 - 2.5e-132 442.2 0.1 2.8e-132 442.1 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I PCIF1_WW PF12237.8 RLN90151.1 - 9e-50 168.6 0.3 1.5e-49 167.9 0.3 1.3 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain SMC_N PF02463.19 RLN90152.1 - 5.1e-59 199.4 18.7 2.4e-58 197.2 18.7 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 RLN90152.1 - 3.2e-28 98.4 0.2 1.1e-26 93.4 0.0 2.8 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 RLN90152.1 - 7.7e-12 45.6 4.1 1.6e-05 24.9 0.0 3.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RLN90152.1 - 1.6e-11 44.5 0.9 1.6e-11 44.5 0.9 4.1 2 2 1 3 3 3 1 AAA ATPase domain AAA_23 PF13476.6 RLN90152.1 - 0.00018 22.1 47.0 0.00018 22.1 47.0 6.4 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 RLN90152.1 - 0.0025 17.5 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain CHASE2 PF05226.11 RLN90152.1 - 0.12 12.1 0.0 0.28 10.8 0.0 1.8 1 0 0 1 1 1 0 CHASE2 domain LPP PF04728.13 RLN90152.1 - 2.2 8.7 33.5 0.28 11.6 0.9 8.2 7 4 1 8 8 8 0 Lipoprotein leucine-zipper Peptidase_M76 PF09768.9 RLN90153.1 - 4.6e-28 98.1 2.0 7.7e-28 97.4 2.0 1.4 1 0 0 1 1 1 1 Peptidase M76 family zf-CCCH PF00642.24 RLN90153.1 - 3e-06 27.0 3.2 2.1e-05 24.3 3.8 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Peptidase_M91 PF14891.6 RLN90153.1 - 0.069 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Effector protein Ribosomal_L12 PF00542.19 RLN90154.1 - 5.5e-27 93.9 10.3 1.2e-26 92.8 10.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 RLN90154.1 - 2e-10 40.2 1.1 2e-10 40.2 1.1 3.5 4 0 0 4 4 4 2 Ribosomal protein L7/L12 dimerisation domain DUF3072 PF11272.8 RLN90154.1 - 0.27 11.2 4.4 1.5 8.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) Mad3_BUB1_I PF08311.12 RLN90155.1 - 0.052 13.5 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 MIP PF00230.20 RLN90156.1 - 6.9e-43 147.0 13.8 8.9e-43 146.6 13.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein Pkinase PF00069.25 RLN90157.1 - 4.2e-49 167.3 0.0 5.3e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90157.1 - 2.6e-23 82.6 0.0 3.9e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase MIP PF00230.20 RLN90158.1 - 1.8e-41 142.4 11.5 2.3e-41 142.0 11.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein AMP-binding PF00501.28 RLN90159.1 - 3.2e-58 197.3 0.2 3.7e-55 187.2 0.2 2.2 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN90159.1 - 0.00028 21.8 0.0 0.00057 20.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Gln-synt_C PF00120.24 RLN90160.1 - 0.00029 19.9 0.0 0.00032 19.8 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain PX PF00787.24 RLN90162.1 - 0.00017 21.6 0.0 0.00024 21.0 0.0 1.2 1 0 0 1 1 1 1 PX domain PX PF00787.24 RLN90163.1 - 0.0012 18.8 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 PX domain AAA_9 PF12781.7 RLN90165.1 - 2e-80 269.0 1.9 2e-80 269.0 1.9 2.6 3 0 0 3 3 3 1 ATP-binding dynein motor region MT PF12777.7 RLN90165.1 - 1.2e-34 119.9 0.7 1.8e-34 119.3 0.7 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RLN90165.1 - 2.5e-20 72.8 3.4 1.2e-19 70.5 0.0 3.6 5 0 0 5 5 5 1 Dynein heavy chain region D6 P-loop domain CBAH PF02275.18 RLN90165.1 - 0.031 13.9 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family COG2 PF06148.11 RLN90165.1 - 0.046 13.8 3.4 0.13 12.4 3.4 1.7 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 FPN1 PF06963.12 RLN90165.1 - 0.083 11.4 0.7 0.14 10.7 0.7 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Lectin_N PF03954.14 RLN90165.1 - 0.12 12.1 4.2 0.28 10.9 0.4 2.7 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain FemAB PF02388.16 RLN90165.1 - 0.25 10.2 2.7 0.45 9.3 2.7 1.3 1 0 0 1 1 1 0 FemAB family Band_7 PF01145.25 RLN90165.1 - 0.69 9.9 2.9 0.83 9.6 0.2 2.3 2 0 0 2 2 2 0 SPFH domain / Band 7 family Phage_Nu1 PF07471.12 RLN90165.1 - 2.4 7.9 6.2 0.23 11.2 0.6 2.1 2 0 0 2 2 2 0 Phage DNA packaging protein Nu1 PH PF00169.29 RLN90168.1 - 2.5e-08 34.4 0.2 1.3e-07 32.1 0.2 2.1 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN90168.1 - 8.7e-05 22.7 0.2 0.00032 20.9 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 RLN90168.1 - 0.00082 19.8 0.1 0.0034 17.8 0.1 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain FA_desaturase PF00487.24 RLN90169.1 - 3e-31 109.2 18.4 4.8e-31 108.5 18.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 RLN90169.1 - 0.19 11.9 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Pkinase PF00069.25 RLN90170.1 - 2.4e-11 43.5 0.0 9.7e-06 25.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90170.1 - 0.0084 15.4 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase SET PF00856.28 RLN90174.1 - 1e-13 52.0 0.6 2.7e-12 47.4 0.0 3.2 3 1 0 3 3 3 1 SET domain preSET_CXC PF18264.1 RLN90174.1 - 7e-12 45.6 15.6 7e-12 45.6 15.6 3.3 2 1 0 2 2 2 1 CXC domain Peptidase_M41 PF01434.18 RLN90175.1 - 4.3e-62 209.4 0.2 8.2e-62 208.4 0.2 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 RLN90175.1 - 5.4e-44 149.8 0.0 1.1e-43 148.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RLN90175.1 - 3.5e-12 45.9 1.6 1.6e-11 43.8 0.2 2.5 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 RLN90175.1 - 1.5e-05 24.8 0.0 3.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RLN90175.1 - 1.7e-05 24.9 0.0 5.7e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RLN90175.1 - 2.5e-05 24.7 0.2 0.0017 18.8 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 RLN90175.1 - 9e-05 21.8 0.0 0.00017 20.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 RLN90175.1 - 0.00016 21.9 0.2 0.069 13.4 0.1 2.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RLN90175.1 - 0.0033 17.2 0.1 0.0091 15.7 0.0 1.9 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 RLN90175.1 - 0.0066 17.0 0.0 0.02 15.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 RLN90175.1 - 0.0087 16.3 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 RLN90175.1 - 0.018 14.4 0.5 0.043 13.2 0.5 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 RLN90175.1 - 0.025 14.8 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 RLN90175.1 - 0.025 14.6 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 RLN90175.1 - 0.026 14.6 0.0 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 RLN90175.1 - 0.029 14.8 0.2 0.1 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 RLN90175.1 - 0.075 13.1 0.0 0.33 11.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) ATPase PF06745.13 RLN90175.1 - 0.082 12.2 0.2 0.45 9.8 0.0 2.1 2 0 0 2 2 2 0 KaiC Sigma54_activat PF00158.26 RLN90175.1 - 0.089 12.5 0.0 0.25 11.0 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 RLN90175.1 - 0.093 12.2 0.1 0.58 9.7 0.1 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 RLN90175.1 - 0.15 12.0 0.4 0.45 10.4 0.1 1.9 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 RLN90175.1 - 0.17 11.3 0.6 0.5 9.8 0.3 1.9 2 0 0 2 2 2 0 PhoH-like protein HTH_WhiA PF02650.14 RLN90175.1 - 0.18 12.1 0.2 0.99 9.8 0.1 2.3 2 0 0 2 2 1 0 WhiA C-terminal HTH domain Parvo_NS1 PF01057.17 RLN90175.1 - 0.25 10.4 0.0 0.43 9.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_8 PF12780.7 RLN90176.1 - 1.2e-101 339.5 0.0 1.9e-101 338.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 RLN90176.1 - 6.8e-101 337.5 0.6 1.9e-100 336.1 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 RLN90176.1 - 4.1e-84 281.1 4.6 6e-83 277.3 0.0 3.1 3 0 0 3 3 3 2 ATP-binding dynein motor region AAA_lid_11 PF18198.1 RLN90176.1 - 1.3e-51 174.6 0.0 2.6e-51 173.7 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RLN90176.1 - 2.8e-47 159.7 0.0 2e-43 147.2 0.0 2.9 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 RLN90176.1 - 1.8e-41 142.3 15.1 2.8e-41 141.7 15.1 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 RLN90176.1 - 9.1e-16 57.9 0.7 4.2e-15 55.8 0.1 2.5 3 0 0 3 3 3 1 AAA+ lid domain Ribosomal_L27e PF01777.18 RLN90176.1 - 6.9 7.1 6.6 0.61 10.5 0.3 2.6 2 0 0 2 2 2 0 Ribosomal L27e protein family SKN1 PF03935.15 RLN90177.1 - 4.7e-53 180.3 14.1 7.3e-35 120.3 4.3 5.1 3 2 0 3 3 3 2 Beta-glucan synthesis-associated protein (SKN1) OAD_gamma PF04277.13 RLN90177.1 - 0.00015 22.3 0.2 0.00028 21.4 0.2 1.4 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain EphA2_TM PF14575.6 RLN90177.1 - 0.02 15.8 0.0 0.19 12.6 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Herpes_capsid PF06112.11 RLN90177.1 - 2.3 8.2 10.9 39 4.2 0.0 2.5 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein ubiquitin PF00240.23 RLN90178.1 - 1.6e-10 40.6 0.0 3.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RLN90178.1 - 0.00018 21.2 0.0 0.00069 19.4 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 RLN90178.1 - 0.00031 21.4 0.0 0.00061 20.4 0.0 1.5 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD PRP38_assoc PF12871.7 RLN90179.1 - 0.0083 16.7 44.9 0.011 16.4 44.9 1.1 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term ABC_tran PF00005.27 RLN90181.1 - 2.3e-07 31.4 0.1 4.3e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 RLN90181.1 - 0.00051 20.5 0.0 0.001 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RLN90181.1 - 0.0015 18.8 0.1 0.0037 17.5 0.0 1.7 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RLN90181.1 - 0.0057 16.0 0.1 0.012 14.9 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 RLN90181.1 - 0.0063 16.2 0.9 0.012 15.4 0.4 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.13 RLN90181.1 - 0.009 15.2 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 RLN90181.1 - 0.0095 15.9 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 RLN90181.1 - 0.027 14.5 0.0 0.065 13.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATPase PF06745.13 RLN90181.1 - 0.034 13.5 1.7 0.72 9.2 0.3 2.5 2 1 1 3 3 3 0 KaiC Ploopntkinase3 PF18751.1 RLN90181.1 - 0.038 13.9 0.1 0.076 12.9 0.0 1.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF87 PF01935.17 RLN90181.1 - 0.059 13.5 0.3 0.14 12.2 0.1 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_18 PF13238.6 RLN90181.1 - 0.065 13.8 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 RLN90181.1 - 0.066 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 RLN90181.1 - 0.1 13.0 0.1 0.46 10.9 0.0 1.9 2 1 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 RLN90181.1 - 0.1 12.1 0.2 0.2 11.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain VirE PF05272.11 RLN90181.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E Cu-oxidase_3 PF07732.15 RLN90182.1 - 2.6e-29 101.6 1.8 8.9e-28 96.7 0.3 2.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 RLN90182.1 - 4.2e-27 95.2 0.0 2e-26 93.0 0.0 2.3 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 RLN90182.1 - 3.4e-19 68.9 7.6 3.5e-15 56.0 0.3 4.2 3 2 0 3 3 3 2 Multicopper oxidase DUF3881 PF12997.7 RLN90182.1 - 0.086 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) DSPc PF00782.20 RLN90184.1 - 2.8e-21 75.7 0.1 3.8e-21 75.3 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Peptidase_S28 PF05577.12 RLN90185.1 - 5.5e-108 361.5 0.0 6.5e-108 361.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 RLN90185.1 - 0.0015 18.0 0.1 0.0026 17.3 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PsaA_PsaB PF00223.19 RLN90185.1 - 0.084 11.1 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein Tad PF13400.6 RLN90185.1 - 0.33 11.3 2.0 1.1 9.6 2.0 1.9 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like FYVE PF01363.21 RLN90186.1 - 4.4e-11 42.8 13.9 1.8e-10 40.8 13.9 2.1 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN90186.1 - 0.00053 20.2 6.2 0.0013 19.0 6.2 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger Cytochrom_C550 PF14495.6 RLN90186.1 - 0.037 13.7 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c-550 domain DUF2439 PF10382.9 RLN90187.1 - 1.1e-11 44.9 0.1 1.4e-11 44.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) tRNA_bind PF01588.20 RLN90188.1 - 9.9e-20 70.5 0.4 1.3e-19 70.0 0.4 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain 4HBT PF03061.22 RLN90189.1 - 2.8e-07 30.8 0.8 0.00031 21.0 0.0 3.2 2 1 0 2 2 2 2 Thioesterase superfamily eIF-3_zeta PF05091.12 RLN90192.1 - 1.3e-178 595.3 0.0 1.4e-178 595.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RE_LlaMI PF09562.10 RLN90193.1 - 0.056 13.0 0.0 0.062 12.9 0.0 1.0 1 0 0 1 1 1 0 LlaMI restriction endonuclease Glyco_hydro_7 PF00840.20 RLN90194.1 - 9.9e-125 416.7 11.0 1.5e-124 416.0 11.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 PPP4R2 PF09184.11 RLN90194.1 - 0.051 13.2 8.6 0.073 12.6 8.6 1.2 1 0 0 1 1 1 0 PPP4R2 SAPS PF04499.15 RLN90194.1 - 3.5 6.3 4.9 4.6 5.9 4.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mito_carr PF00153.27 RLN90195.1 - 9.6e-28 96.0 3.7 3.5e-12 46.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Exo_endo_phos PF03372.23 RLN90196.1 - 3.5e-09 36.5 0.0 8.5e-09 35.3 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MORN PF02493.20 RLN90196.1 - 1e-07 31.4 8.6 0.014 15.2 0.7 3.6 3 0 0 3 3 3 3 MORN repeat TolA_bind_tri PF16331.5 RLN90196.1 - 0.0018 18.3 0.4 0.0043 17.1 0.4 1.5 1 0 0 1 1 1 1 TolA binding protein trimerisation KLRAQ PF10205.9 RLN90196.1 - 6.6 7.0 6.3 1.4 9.2 1.7 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein CNOT11 PF10155.9 RLN90197.1 - 3.3e-40 137.1 2.8 6.3e-40 136.2 2.8 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 WW PF00397.26 RLN90197.1 - 0.14 12.3 1.9 0.16 12.1 0.2 2.0 2 0 0 2 2 2 0 WW domain Frataxin_Cyay PF01491.16 RLN90198.1 - 0.00037 20.5 0.0 0.0004 20.4 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Q_salvage PF10343.9 RLN90199.1 - 1.5e-21 77.2 0.0 1.8e-20 73.7 0.0 2.0 1 1 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF5478 PF17572.2 RLN90199.1 - 0.039 14.1 0.0 0.1 12.7 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5478) PX PF00787.24 RLN90200.1 - 0.00035 20.5 0.0 0.00074 19.5 0.0 1.6 2 0 0 2 2 2 1 PX domain GMC_oxred_N PF00732.19 RLN90201.1 - 1.5e-21 77.1 0.0 3.7e-21 75.8 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 RLN90201.1 - 1e-10 42.3 0.9 1.9e-10 41.4 0.5 1.7 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 RLN90201.1 - 4.7e-07 29.9 0.4 6.2e-06 26.4 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 RLN90201.1 - 4.1e-06 26.2 0.8 0.0028 16.8 0.5 2.5 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 RLN90201.1 - 4.1e-05 23.0 0.1 8.6e-05 21.9 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 RLN90201.1 - 0.00029 20.1 0.3 0.00054 19.3 0.3 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 RLN90201.1 - 0.00083 18.7 0.3 0.0013 18.0 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 RLN90201.1 - 0.006 15.3 0.6 0.012 14.4 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 RLN90201.1 - 0.0063 15.4 0.0 0.009 14.9 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.24 RLN90201.1 - 0.0074 15.9 0.9 0.032 13.8 0.5 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 RLN90201.1 - 0.01 15.2 1.0 0.12 11.7 0.9 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 RLN90201.1 - 0.021 13.9 1.0 0.044 12.8 0.4 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein HMG_CoA_synt_C PF08540.10 RLN90202.1 - 4.7e-53 180.6 0.1 7.1e-53 180.0 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ketoacyl-synt PF00109.26 RLN90202.1 - 9.2e-16 58.2 5.6 3.5e-15 56.3 5.6 2.0 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain HMG_CoA_synt_N PF01154.17 RLN90202.1 - 8.1e-14 51.9 0.2 3.4e-11 43.3 0.0 2.4 2 0 0 2 2 2 2 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.10 RLN90202.1 - 7.7e-08 32.1 2.1 4e-07 29.8 0.8 2.4 1 1 1 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 RLN90202.1 - 0.026 14.7 0.0 0.087 13.0 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Spem1 PF15670.5 RLN90203.1 - 0.57 9.7 3.8 0.78 9.3 3.8 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 Dicty_REP PF05086.12 RLN90203.1 - 0.98 7.3 5.6 1.2 7.1 5.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Orai-1 PF07856.12 RLN90204.1 - 1.8e-09 37.5 0.0 3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Mediator of CRAC channel activity Synaphin PF05835.12 RLN90204.1 - 0.049 13.9 1.1 0.06 13.6 1.1 1.1 1 0 0 1 1 1 0 Synaphin protein TMEM237 PF15383.6 RLN90204.1 - 0.055 12.6 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 Beta-lactamase PF00144.24 RLN90205.1 - 1.3e-32 113.3 0.1 2.2e-32 112.6 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF2239 PF09998.9 RLN90205.1 - 0.087 12.6 0.4 0.15 11.8 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2239) Orai-1 PF07856.12 RLN90206.1 - 3.1e-31 108.4 4.8 4.4e-31 107.9 4.8 1.2 1 0 0 1 1 1 1 Mediator of CRAC channel activity Jiraiya PF15038.6 RLN90206.1 - 0.005 16.3 9.8 0.013 14.9 9.8 1.8 1 1 0 1 1 1 1 Jiraiya AA_kinase PF00696.28 RLN90207.1 - 8.2e-39 133.6 0.3 1.4e-38 132.9 0.3 1.4 1 0 0 1 1 1 1 Amino acid kinase family Homoserine_dh PF00742.19 RLN90207.1 - 6e-25 88.1 0.0 1.2e-24 87.1 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase Orai-1 PF07856.12 RLN90207.1 - 2.2e-13 50.3 3.8 4.6e-13 49.2 3.8 1.5 1 0 0 1 1 1 1 Mediator of CRAC channel activity ACT_7 PF13840.6 RLN90207.1 - 6.5e-12 45.1 0.9 1.7e-07 30.9 0.0 2.9 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 RLN90207.1 - 3.7e-10 39.4 3.2 6.6e-05 22.6 0.0 3.2 3 0 0 3 3 3 2 ACT domain NAD_binding_3 PF03447.16 RLN90207.1 - 3.3e-06 27.8 0.4 2.8e-05 24.7 0.1 2.5 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain BioW PF03744.13 RLN90207.1 - 0.048 13.2 0.2 0.087 12.4 0.2 1.4 1 0 0 1 1 1 0 6-carboxyhexanoate--CoA ligase Jiraiya PF15038.6 RLN90207.1 - 0.076 12.4 1.5 0.19 11.1 1.5 1.7 1 0 0 1 1 1 0 Jiraiya PARP PF00644.20 RLN90208.1 - 2.3e-23 82.8 0.0 4.1e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 RLN90208.1 - 2.1e-14 53.8 0.0 3.3e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 RLN90208.1 - 3e-09 36.8 0.0 6e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 WGR domain Securin PF04856.13 RLN90208.1 - 0.16 11.9 1.5 0.28 11.1 1.5 1.4 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor p450 PF00067.22 RLN90210.1 - 9.9e-76 255.3 0.0 1.2e-75 255.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 RLN90211.1 - 2.2e-70 237.7 0.0 2.7e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NA37 PF04245.13 RLN90211.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein ATP19 PF11022.8 RLN90211.1 - 0.14 12.5 0.1 0.36 11.2 0.1 1.6 1 0 0 1 1 1 0 ATP synthase subunit K p450 PF00067.22 RLN90212.1 - 8.1e-77 258.9 0.0 1e-76 258.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 RLN90213.1 - 4.6e-59 200.4 0.0 5.2e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tub PF01167.18 RLN90214.1 - 1.3e-16 61.1 0.0 4.8e-16 59.3 0.0 1.7 1 1 0 1 1 1 1 Tub family p450 PF00067.22 RLN90215.1 - 3.8e-76 256.7 0.0 4.9e-76 256.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-CCCH PF00642.24 RLN90217.1 - 7.8e-22 76.7 25.3 1.1e-05 25.1 0.5 4.4 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 RLN90217.1 - 1.5e-18 67.5 21.7 1.6e-05 25.6 0.2 4.9 4 1 1 5 5 5 4 Torus domain zf_CCCH_4 PF18345.1 RLN90217.1 - 1.5e-17 63.0 38.3 5.7e-05 23.0 0.7 4.3 4 0 0 4 4 4 4 Zinc finger domain zf-CCCH_4 PF18044.1 RLN90217.1 - 4e-16 58.4 29.5 6.4e-06 25.8 2.9 4.3 4 0 0 4 4 4 4 CCCH-type zinc finger zf-B_box PF00643.24 RLN90217.1 - 1.3e-09 38.0 16.6 1.8e-07 31.2 5.1 2.5 2 0 0 2 2 2 2 B-box zinc finger R3H PF01424.22 RLN90217.1 - 7.4e-09 35.5 0.0 2e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 R3H domain zf-CCCH_2 PF14608.6 RLN90217.1 - 1.5e-07 31.6 29.3 0.014 15.9 2.2 4.5 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger zf-HIT PF04438.16 RLN90217.1 - 0.01 15.7 3.3 0.01 15.7 3.3 3.2 3 0 0 3 3 3 0 HIT zinc finger zf-C2H2_jaz PF12171.8 RLN90217.1 - 0.013 15.7 1.0 1.2 9.5 0.0 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-CCCH_3 PF15663.5 RLN90217.1 - 0.035 14.3 23.0 0.051 13.8 0.0 4.7 4 1 0 4 4 3 0 Zinc-finger containing family C1_4 PF07975.12 RLN90217.1 - 0.044 14.0 13.5 0.059 13.6 0.9 3.4 2 1 0 2 2 2 0 TFIIH C1-like domain IBR PF01485.21 RLN90217.1 - 4.4 7.6 20.1 5.4 7.3 6.1 2.9 1 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf_C2H2_ZHX PF18387.1 RLN90217.1 - 7.2 6.3 7.1 0.71 9.6 0.2 2.8 2 1 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain eIF-5_eIF-2B PF01873.17 RLN90218.1 - 2.1e-38 130.8 1.0 2.9e-38 130.3 0.1 1.6 2 0 0 2 2 2 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.6 RLN90218.1 - 0.0034 17.7 0.0 0.01 16.2 0.0 2.0 1 0 0 1 1 1 1 Restriction alleviation protein Lar zinc_ribbon_6 PF14599.6 RLN90218.1 - 0.033 14.2 0.7 11 6.2 0.1 2.5 2 0 0 2 2 2 0 Zinc-ribbon CMS1 PF14617.6 RLN90218.1 - 0.28 10.5 2.9 0.4 10.0 2.9 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Fer4 PF00037.27 RLN90219.1 - 9.1e-09 34.8 4.5 1.5e-08 34.1 4.5 1.4 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_7 PF12838.7 RLN90219.1 - 6.1e-07 29.9 0.1 1e-06 29.2 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 RLN90219.1 - 2.1e-05 25.4 0.1 4.1e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 RLN90219.1 - 0.00013 22.0 0.3 0.00024 21.2 0.1 1.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 RLN90219.1 - 0.00027 21.3 0.1 0.00052 20.4 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 RLN90219.1 - 0.00066 19.8 1.1 0.00094 19.3 0.4 1.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 RLN90219.1 - 0.00082 19.5 0.1 0.0015 18.6 0.1 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 RLN90219.1 - 0.0012 18.8 2.0 0.0023 17.9 2.0 1.5 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_17 PF13534.6 RLN90219.1 - 0.0025 18.3 0.4 0.0053 17.3 0.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 RLN90219.1 - 0.0065 16.5 4.5 0.013 15.6 4.5 1.5 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_18 PF13746.6 RLN90219.1 - 0.067 13.4 0.2 0.12 12.6 0.2 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 RLN90219.1 - 2.6 9.2 8.0 0.3 12.1 4.1 1.5 2 0 0 2 2 1 0 4Fe-4S binding domain TFIIIC_sub6 PF10419.9 RLN90220.1 - 4.9e-07 29.5 0.1 1.8e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 TFIIIC subunit triple barrel domain TBCC PF07986.12 RLN90221.1 - 4.2e-30 104.0 0.0 6.7e-30 103.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 RLN90221.1 - 1.7e-19 70.4 0.3 1.7e-19 70.4 0.3 2.1 2 1 0 2 2 2 1 Tubulin-specific chaperone C N-terminal domain CAP_GLY PF01302.25 RLN90221.1 - 6.5e-16 58.1 0.0 1.3e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain RPA43_OB PF17875.1 RLN90222.1 - 1.3e-07 32.3 8.4 1.2e-05 25.9 0.0 3.3 2 1 1 3 3 3 2 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 RLN90222.1 - 2.2e-06 27.9 0.0 4.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF4604 PF15377.6 RLN90222.1 - 0.22 11.9 17.9 0.29 11.5 17.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) MULE PF10551.9 RLN90223.1 - 2.7e-08 34.1 0.0 6e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Xpo1 PF08389.12 RLN90224.1 - 2.2e-17 63.5 0.0 3.7e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Exportin 1-like protein ABC_tran PF00005.27 RLN90225.1 - 2.4e-16 60.5 0.0 3e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 RLN90226.1 - 2.2e-57 194.8 32.7 9.7e-34 117.3 6.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN90226.1 - 4.4e-50 169.8 0.0 3.2e-27 95.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 RLN90226.1 - 1.6e-08 34.6 0.6 0.0067 16.5 0.2 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 RLN90226.1 - 8.4e-08 31.9 0.8 0.076 12.4 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RLN90226.1 - 2.7e-07 30.7 2.5 0.27 11.0 0.0 3.8 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN90226.1 - 1.4e-05 24.8 0.2 0.061 13.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN90226.1 - 1.4e-05 25.5 0.7 0.01 16.2 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 RLN90226.1 - 0.00016 22.2 0.0 0.93 10.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 RLN90226.1 - 0.00024 21.1 4.5 0.03 14.2 0.2 3.2 3 0 0 3 3 3 2 RsgA GTPase Dynamin_N PF00350.23 RLN90226.1 - 0.00025 21.1 0.0 0.033 14.3 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_24 PF13479.6 RLN90226.1 - 0.00059 19.6 0.1 0.028 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RLN90226.1 - 0.0023 17.2 0.9 0.022 14.1 0.1 2.5 3 0 0 3 3 3 1 Zeta toxin AAA_7 PF12775.7 RLN90226.1 - 0.0027 17.2 0.1 0.21 11.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 RLN90226.1 - 0.0044 16.2 1.1 0.48 9.5 0.2 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 RLN90226.1 - 0.0047 17.2 0.7 3.2 8.0 0.1 3.2 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.6 RLN90226.1 - 0.006 16.2 0.0 0.38 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 RLN90226.1 - 0.0077 16.4 3.3 0.036 14.2 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain Roc PF08477.13 RLN90226.1 - 0.025 14.8 0.1 7.1 6.9 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 RLN90226.1 - 0.037 14.6 0.0 18 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 RLN90226.1 - 0.061 13.1 0.9 8.9 6.0 0.0 3.2 4 0 0 4 4 4 0 IstB-like ATP binding protein DUF4523 PF15023.6 RLN90226.1 - 0.081 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) DEAD PF00270.29 RLN90226.1 - 0.086 12.6 0.2 0.7 9.6 0.0 2.4 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_28 PF13521.6 RLN90226.1 - 0.11 12.7 0.0 0.74 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 RLN90226.1 - 0.12 11.9 0.3 3.6 7.1 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 RLN90226.1 - 0.13 12.4 0.0 2.7 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain CHB_HEX PF03173.13 RLN90228.1 - 0.11 12.2 0.5 0.2 11.3 0.5 1.5 1 1 0 1 1 1 0 Putative carbohydrate binding domain Ribonuc_red_lgC PF02867.15 RLN90229.1 - 0.4 9.2 1.8 0.5 8.8 1.8 1.1 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain K-box PF01486.17 RLN90230.1 - 6e-08 32.8 3.5 1.2e-07 31.8 3.5 1.4 1 0 0 1 1 1 1 K-box region Dynamitin PF04912.14 RLN90230.1 - 0.36 10.1 6.7 3 7.1 6.7 1.9 1 1 0 1 1 1 0 Dynamitin HIP1_clath_bdg PF16515.5 RLN90230.1 - 0.47 11.1 5.8 0.93 10.1 1.9 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 RLN90230.1 - 2.4 8.7 7.6 5 7.7 2.8 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region BST2 PF16716.5 RLN90230.1 - 5.1 7.7 6.5 2.1 9.0 2.8 2.1 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 MutL_C PF08676.11 RLN90232.1 - 1.6e-20 73.4 0.2 4.6e-20 71.9 0.2 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 RLN90232.1 - 9.9e-08 31.7 0.3 7.3e-07 28.9 0.0 2.6 2 1 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 RLN90232.1 - 3.5e-07 30.1 0.0 9.4e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 RLN90232.1 - 6.6e-06 26.6 0.0 1.8e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ABC2_membrane PF01061.24 RLN90233.1 - 2.6e-29 102.2 26.7 4.5e-29 101.4 26.7 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN90233.1 - 5.2e-21 75.6 0.0 8.4e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN90233.1 - 2.7e-10 40.6 0.0 9.4e-05 22.4 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN90233.1 - 1.1e-05 25.9 0.0 2.4e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 RLN90233.1 - 0.00091 18.9 0.1 0.0025 17.5 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN90233.1 - 0.00092 19.8 0.0 0.0016 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 RLN90233.1 - 0.0019 17.8 0.0 0.0065 16.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RLN90233.1 - 0.0022 18.2 0.0 0.0064 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 RLN90233.1 - 0.0075 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 RLN90233.1 - 0.01 15.3 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 RLN90233.1 - 0.023 14.4 0.1 0.042 13.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RLN90233.1 - 0.025 14.8 0.5 0.16 12.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 RLN90233.1 - 0.047 13.6 0.0 0.64 9.9 0.0 2.1 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.12 RLN90233.1 - 0.072 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 RLN90233.1 - 0.077 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 RLN90233.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 RLN90233.1 - 0.18 10.8 0.1 0.3 10.0 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 RLN90233.1 - 0.2 12.2 0.0 0.37 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 RLN90233.1 - 2.6 7.0 27.0 4.1 6.4 27.0 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane PF01061.24 RLN90234.1 - 4.5e-28 98.1 21.2 8.1e-28 97.3 21.2 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN90234.1 - 3.2e-21 76.3 0.0 5.1e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN90234.1 - 1.7e-10 41.3 0.0 0.00046 20.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 RLN90234.1 - 0.00015 21.4 0.0 0.00091 18.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN90234.1 - 0.00018 21.9 0.1 0.00081 19.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 RLN90234.1 - 0.00089 19.0 0.1 0.0022 17.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN90234.1 - 0.0021 18.6 0.2 0.0037 17.8 0.2 1.2 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 RLN90234.1 - 0.0082 16.1 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 1 NTPase AAA_22 PF13401.6 RLN90234.1 - 0.0095 16.2 0.0 0.021 15.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RLN90234.1 - 0.013 15.2 0.1 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RLN90234.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 RLN90234.1 - 0.037 14.3 0.1 0.07 13.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RLN90234.1 - 0.09 13.3 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 RLN90234.1 - 0.11 12.0 0.0 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 RLN90234.1 - 0.16 11.8 0.1 0.38 10.6 0.1 1.6 1 0 0 1 1 1 0 NACHT domain ABC2_membrane_3 PF12698.7 RLN90234.1 - 0.25 10.4 21.1 0.47 9.5 20.4 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein CRAL_TRIO PF00650.20 RLN90235.1 - 0.03 14.0 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 CRAL/TRIO domain SR-25 PF10500.9 RLN90237.1 - 0.0081 15.8 16.3 0.066 12.8 4.9 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF3295 PF11702.8 RLN90237.1 - 0.022 14.1 17.9 0.028 13.8 17.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) FAM76 PF16046.5 RLN90237.1 - 0.029 13.7 15.6 0.47 9.8 3.8 2.1 2 0 0 2 2 2 0 FAM76 protein FHIPEP PF00771.20 RLN90237.1 - 0.042 12.3 3.4 0.078 11.4 3.4 1.4 1 0 0 1 1 1 0 FHIPEP family DUF775 PF05603.12 RLN90237.1 - 0.071 12.6 14.0 0.022 14.3 10.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF775) UPF0524 PF15823.5 RLN90237.1 - 0.18 11.2 4.5 0.36 10.2 4.5 1.5 1 0 0 1 1 1 0 UPF0524 of C3orf70 Nucleo_P87 PF07267.11 RLN90237.1 - 0.33 9.8 9.5 0.46 9.3 9.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Macoilin PF09726.9 RLN90237.1 - 0.55 8.7 20.0 0.7 8.4 20.0 1.1 1 0 0 1 1 1 0 Macoilin family Itfg2 PF15907.5 RLN90237.1 - 1.1 8.2 6.3 2 7.4 6.3 1.3 1 0 0 1 1 1 0 Integrin-alpha FG-GAP repeat-containing protein 2 Peptidase_S64 PF08192.11 RLN90237.1 - 2.3 6.6 15.7 3 6.2 15.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 AAA_23 PF13476.6 RLN90237.1 - 2.8 8.4 18.0 0.47 10.9 6.6 2.2 2 0 0 2 2 2 0 AAA domain Ndc1_Nup PF09531.10 RLN90237.1 - 3.2 6.3 15.2 4.6 5.8 15.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Methyltransf_32 PF13679.6 RLN90237.1 - 3.3 7.7 11.8 4.9 7.1 3.4 2.6 2 1 1 3 3 3 0 Methyltransferase domain Pal1 PF08316.11 RLN90237.1 - 7.9 7.2 12.0 4.3 8.1 3.6 2.6 2 1 0 2 2 2 0 Pal1 cell morphology protein MIP PF00230.20 RLN90238.1 - 6.6e-51 173.2 8.1 6.6e-51 173.2 8.1 1.8 1 1 1 2 2 2 1 Major intrinsic protein NQR2_RnfD_RnfE PF03116.15 RLN90238.1 - 0.0025 17.3 2.2 0.0025 17.3 2.2 1.5 1 1 0 1 1 1 1 NQR2, RnfD, RnfE family Mon2_C PF16206.5 RLN90239.1 - 3.7e-32 111.4 4.0 1.4e-30 106.2 2.0 3.0 2 1 0 2 2 2 2 C-terminal region of Mon2 protein DCB PF16213.5 RLN90239.1 - 4.7e-27 94.8 1.7 2e-20 73.2 0.1 3.2 2 0 0 2 2 2 2 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 RLN90239.1 - 8e-16 58.3 0.2 3.8e-13 49.7 0.0 4.2 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 RLN90239.1 - 8.6e-06 25.5 0.7 0.0082 16.0 0.0 4.6 4 1 1 5 5 5 1 Domain of unknown function (DUF1981) MIP PF00230.20 RLN90242.1 - 1.6e-50 171.9 6.7 2.2e-50 171.5 6.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF2157 PF09925.9 RLN90242.1 - 0.022 14.5 0.6 2.9 7.7 0.0 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF1418 PF07214.12 RLN90242.1 - 0.23 11.3 0.9 2.1 8.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) DctQ PF04290.12 RLN90242.1 - 1.6 8.7 7.8 0.16 11.8 1.8 2.3 2 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component FYVE PF01363.21 RLN90243.1 - 1e-09 38.3 16.1 2.5e-09 37.1 16.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger GAF_2 PF13185.6 RLN90243.1 - 3.6e-06 27.3 0.0 1.9e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 RLN90243.1 - 0.00013 22.6 0.1 0.00044 20.9 0.1 1.9 1 0 0 1 1 1 1 GAF domain FYVE_2 PF02318.16 RLN90243.1 - 0.00027 21.1 5.4 0.00095 19.4 5.4 1.9 1 0 0 1 1 1 1 FYVE-type zinc finger GAF_3 PF13492.6 RLN90243.1 - 0.035 14.4 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 GAF domain Prok-RING_2 PF14445.6 RLN90243.1 - 0.72 10.1 6.9 2.4 8.4 6.9 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Prok-RING_4 PF14447.6 RLN90243.1 - 1.7 8.6 14.5 0.28 11.1 9.9 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FYVE_2 PF02318.16 RLN90244.1 - 5.8e-05 23.3 4.4 0.00015 22.0 4.4 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger GAF PF01590.26 RLN90244.1 - 0.00019 22.1 0.1 0.001 19.7 0.0 2.3 2 1 0 2 2 2 1 GAF domain FYVE PF01363.21 RLN90244.1 - 0.00021 21.4 12.7 0.0005 20.2 12.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF_2 PF13185.6 RLN90244.1 - 0.00069 19.9 0.0 0.0022 18.3 0.0 1.9 1 0 0 1 1 1 1 GAF domain zf-CRD PF17979.1 RLN90244.1 - 2.9 8.0 9.9 7 6.7 9.9 1.7 1 1 0 1 1 1 0 Cysteine rich domain with multizinc binding regions MIP PF00230.20 RLN90245.1 - 1.6e-50 171.9 6.4 2.1e-50 171.5 6.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein DctQ PF04290.12 RLN90245.1 - 0.9 9.5 5.5 0.099 12.6 0.5 2.0 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component MIP PF00230.20 RLN90246.1 - 1.9e-51 175.0 5.2 2.5e-51 174.6 5.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 RLN90247.1 - 1.5e-50 172.0 6.5 2e-50 171.6 6.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF2157 PF09925.9 RLN90247.1 - 0.084 12.7 2.4 3.2 7.5 0.1 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF1418 PF07214.12 RLN90247.1 - 0.24 11.3 0.9 2.1 8.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) DctQ PF04290.12 RLN90247.1 - 1.6 8.7 7.8 0.16 11.8 1.8 2.3 2 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Polysacc_synt_C PF14667.6 RLN90247.1 - 9 6.3 10.4 0.97 9.5 0.6 2.8 2 1 1 3 3 3 0 Polysaccharide biosynthesis C-terminal domain MIP PF00230.20 RLN90248.1 - 1.1e-50 172.4 6.1 1.6e-50 172.0 6.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein DctQ PF04290.12 RLN90248.1 - 0.83 9.6 5.5 0.094 12.6 0.5 2.0 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component MIP PF00230.20 RLN90249.1 - 3.6e-52 177.3 7.4 4.6e-52 177.0 7.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein DctQ PF04290.12 RLN90249.1 - 0.13 12.2 7.3 0.063 13.2 4.3 2.1 2 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component MIP PF00230.20 RLN90250.1 - 4.6e-50 170.4 10.2 6.1e-50 170.0 10.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein Peptidase_C48 PF02902.19 RLN90251.1 - 1.9e-06 27.9 0.1 5.3e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SWIM PF04434.17 RLN90251.1 - 0.008 15.8 0.5 0.021 14.5 0.5 1.6 1 0 0 1 1 1 1 SWIM zinc finger DIL PF01843.19 RLN90251.1 - 0.045 14.0 0.2 0.43 10.9 0.1 2.6 2 0 0 2 2 2 0 DIL domain Delta_lysin PF05372.11 RLN90251.1 - 0.059 12.7 0.1 15 5.0 0.0 3.1 3 0 0 3 3 3 0 Delta lysin family Dpy-30 PF05186.13 RLN90253.1 - 9.3e-19 66.9 0.3 1.5e-18 66.2 0.3 1.4 1 0 0 1 1 1 1 Dpy-30 motif SMYLE_N PF18615.1 RLN90253.1 - 0.03 13.9 0.5 0.034 13.7 0.5 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain RR_TM4-6 PF06459.12 RLN90253.1 - 0.25 11.1 4.7 0.27 11.0 4.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CT47 PF15623.6 RLN90253.1 - 0.4 10.5 22.5 0.51 10.1 22.5 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 DNA_pol_phi PF04931.13 RLN90253.1 - 2.5 6.1 6.7 2.9 5.9 6.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_Rpc4 PF05132.14 RLN90253.1 - 4.7 7.6 7.2 6.6 7.2 7.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Rad60-SLD PF11976.8 RLN90255.1 - 4.9e-18 64.7 0.0 5.9e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 RLN90255.1 - 2.8e-11 43.0 0.0 3.3e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family OCRL_clath_bd PF16726.5 RLN90255.1 - 0.051 13.7 0.1 1.4 9.1 0.0 2.0 2 0 0 2 2 2 0 Inositol polyphosphate 5-phosphatase clathrin binding domain PH PF00169.29 RLN90256.1 - 5.1e-12 46.2 0.0 2.2e-07 31.3 0.0 2.3 2 0 0 2 2 2 2 PH domain FYVE PF01363.21 RLN90256.1 - 0.0019 18.3 4.5 0.004 17.3 4.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger RhoGEF PF00621.20 RLN90258.1 - 2.5e-24 86.5 0.0 3e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 RhoGEF domain Egg_lysin PF01303.17 RLN90258.1 - 0.19 12.0 0.0 0.9 9.8 0.0 1.9 2 0 0 2 2 2 0 Egg lysin (Sperm-lysin) RNase_H PF00075.24 RLN90259.1 - 1.4e-37 129.1 1.2 1.1e-24 87.2 0.2 2.3 2 0 0 2 2 2 2 RNase H DUF1706 PF08020.11 RLN90259.1 - 0.00011 22.1 0.9 0.0063 16.5 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1706) Collar PF07484.12 RLN90259.1 - 0.0087 16.1 0.1 0.8 9.8 0.0 3.0 3 0 0 3 3 3 1 Phage Tail Collar Domain Ank_2 PF12796.7 RLN90260.1 - 7.2e-14 52.1 4.7 9.2e-09 35.8 0.7 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN90260.1 - 1.4e-12 47.9 2.7 1.2e-05 25.7 0.2 3.7 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN90260.1 - 4.1e-11 42.9 5.0 0.00058 20.1 0.2 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN90260.1 - 6.5e-07 29.2 0.7 3.7 8.4 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 RLN90260.1 - 0.00032 21.0 0.3 20 5.9 0.2 4.4 2 1 1 3 3 3 1 Ankyrin repeat DUF5049 PF16468.5 RLN90260.1 - 0.045 13.7 0.0 5.5 7.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5049) Carn_acyltransf PF00755.20 RLN90261.1 - 1.1e-193 645.1 0.0 1.3e-193 644.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF2542 PF10808.8 RLN90261.1 - 0.0058 17.1 4.2 0.012 16.0 4.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2542) RPN2_C PF18004.1 RLN90263.1 - 3.4 7.6 11.4 1.1 9.1 8.6 1.6 1 1 1 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain PH PF00169.29 RLN90264.1 - 7.2e-07 29.7 0.0 1.5e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN90264.1 - 0.0095 16.3 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain DUF1765 PF08578.10 RLN90265.1 - 9.6e-18 64.8 2.7 9.6e-18 64.8 2.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) PH PF00169.29 RLN90265.1 - 6.7e-08 33.0 0.8 1.7e-07 31.7 0.2 2.1 2 0 0 2 2 2 1 PH domain SNAP PF14938.6 RLN90266.1 - 0.0022 17.5 2.0 0.012 15.1 0.3 2.6 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 RLN90266.1 - 0.0045 17.0 7.5 13 6.2 0.0 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN90266.1 - 0.097 12.7 7.1 13 6.1 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN90266.1 - 1.2 9.1 9.6 10 6.1 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Myb_DNA-bind_4 PF13837.6 RLN90267.1 - 0.00012 22.4 0.1 0.00027 21.2 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Ldl_recept_b PF00058.17 RLN90267.1 - 0.008 16.6 7.4 2.9 8.5 0.1 5.4 5 0 0 5 5 5 1 Low-density lipoprotein receptor repeat class B TIG PF01833.24 RLN90267.1 - 0.018 15.1 0.0 0.058 13.5 0.0 1.8 1 0 0 1 1 1 0 IPT/TIG domain VPS9 PF02204.18 RLN90268.1 - 1.5e-11 44.5 0.0 3.1e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CAP PF00188.26 RLN90269.1 - 2.2e-23 83.5 3.2 3e-23 83.0 3.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 RLN90270.1 - 1.9e-23 83.6 0.6 2.5e-23 83.3 0.6 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family FYVE PF01363.21 RLN90271.1 - 3.4e-15 55.9 10.4 5.7e-15 55.2 10.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger Ank_5 PF13857.6 RLN90271.1 - 0.0011 19.2 0.0 0.0034 17.7 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN90271.1 - 0.12 13.0 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) RXT2_N PF08595.11 RLN90271.1 - 0.54 10.3 4.1 1.2 9.2 4.1 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal FYVE_2 PF02318.16 RLN90271.1 - 1 9.6 4.9 2.1 8.6 4.9 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger DZR PF12773.7 RLN90271.1 - 7.1 6.7 8.9 47 4.1 9.0 2.1 1 1 0 1 1 1 0 Double zinc ribbon Exonuc_VII_S PF02609.16 RLN90273.1 - 0.025 14.6 0.1 1.8 8.7 0.0 2.3 2 0 0 2 2 2 0 Exonuclease VII small subunit CCDC85 PF10226.9 RLN90273.1 - 0.056 13.1 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 CCDC85 family SnoaL PF07366.12 RLN90273.1 - 0.075 12.8 0.0 0.28 11.0 0.0 2.0 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase TSC22 PF01166.18 RLN90273.1 - 0.098 13.0 0.7 2.7 8.4 0.2 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family zf-RING_2 PF13639.6 RLN90274.1 - 2.9e-08 33.9 12.1 2.9e-08 33.9 12.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 RLN90274.1 - 1.1e-05 25.7 9.2 2.9e-05 24.2 9.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 RLN90274.1 - 0.00016 21.4 10.3 0.00016 21.4 10.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN90274.1 - 0.00017 21.4 11.6 0.00035 20.4 11.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN90274.1 - 0.00026 20.9 8.6 0.00069 19.6 8.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN90274.1 - 0.0012 18.7 11.5 0.0026 17.7 11.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RLN90274.1 - 0.0017 18.1 11.2 0.0038 17.0 11.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RLN90274.1 - 0.015 15.4 0.4 0.015 15.4 0.4 2.2 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RLN90274.1 - 0.021 14.7 8.9 0.053 13.4 8.9 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 RLN90274.1 - 0.038 13.7 7.4 0.08 12.7 7.4 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 RLN90274.1 - 0.081 13.0 5.3 0.22 11.6 5.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 RLN90274.1 - 1.2 8.8 8.4 6 6.6 8.8 2.0 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-UDP PF14569.6 RLN90274.1 - 1.3 9.2 8.0 0.35 11.0 4.2 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger Surp PF01805.20 RLN90276.1 - 3.1e-16 59.1 0.0 5.1e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Surp module Arm PF00514.23 RLN90277.1 - 1.1e-25 88.8 18.4 8.8e-11 41.5 0.2 5.7 4 1 1 5 5 5 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN90277.1 - 4.5e-14 52.6 1.9 1.6e-08 34.9 0.1 3.7 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.22 RLN90277.1 - 6.8e-09 35.2 1.0 0.086 13.2 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 RLN90277.1 - 9.5e-07 29.1 1.4 0.18 12.2 0.2 3.3 1 1 2 3 3 3 2 HEAT repeats Arm_2 PF04826.13 RLN90277.1 - 0.0033 16.9 0.0 0.0062 16.0 0.0 1.4 1 0 0 1 1 1 1 Armadillo-like RCC1 PF00415.18 RLN90278.1 - 2.1e-81 268.4 24.0 1.3e-15 57.7 0.3 8.2 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN90278.1 - 7.5e-17 60.7 52.0 1.2e-07 31.3 3.1 8.1 7 2 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Hid1 PF12722.7 RLN90278.1 - 0.46 8.6 0.8 0.61 8.1 0.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WD40 PF00400.32 RLN90283.1 - 1.1e-06 29.2 0.4 0.027 15.4 0.0 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat 2OG-FeII_Oxy_3 PF13640.6 RLN90284.1 - 0.003 18.4 0.0 0.008 17.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SH3BGR PF04908.15 RLN90285.1 - 7.9e-05 22.7 0.1 0.00012 22.1 0.1 1.4 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 RLN90285.1 - 0.011 16.0 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin TauE PF01925.19 RLN90286.1 - 1.9e-22 80.1 34.1 2.8e-14 53.3 0.9 2.7 2 1 0 2 2 2 2 Sulfite exporter TauE/SafE GST_N PF02798.20 RLN90287.1 - 1.7e-21 76.3 0.0 5.1e-10 39.6 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RLN90287.1 - 3e-19 69.0 0.1 5e-12 45.9 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RLN90287.1 - 1.2e-10 41.7 0.0 0.00016 22.0 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN90287.1 - 7.3e-07 29.4 0.0 0.0083 16.4 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN90287.1 - 4.2e-05 23.5 0.1 0.0026 17.7 0.0 2.9 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RLN90287.1 - 0.017 15.4 0.2 0.16 12.2 0.0 2.6 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 RLN90287.1 - 0.053 14.3 0.0 23 5.8 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain Peptidase_M50 PF02163.22 RLN90287.1 - 0.066 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M50 RPAP1_N PF08621.10 RLN90287.1 - 0.12 12.1 0.6 1.5 8.6 0.1 2.4 2 0 0 2 2 2 0 RPAP1-like, N-terminal bZIP_1 PF00170.21 RLN90288.1 - 1.3e-08 34.8 10.0 1.3e-08 34.8 10.0 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 RLN90288.1 - 1.1e-05 25.4 14.2 2.9e-05 24.0 14.2 1.7 1 0 0 1 1 1 1 Basic region leucine zipper SnoaL_2 PF12680.7 RLN90288.1 - 0.0087 16.7 0.0 0.016 15.8 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain TFIIA PF03153.13 RLN90288.1 - 0.021 14.8 10.8 0.028 14.4 10.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit bZIP_Maf PF03131.17 RLN90288.1 - 0.025 15.1 9.7 0.025 15.1 9.7 2.5 2 1 0 2 2 2 0 bZIP Maf transcription factor IZUMO PF15005.6 RLN90288.1 - 0.041 14.4 0.8 0.041 14.4 0.8 2.1 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated GST_N PF02798.20 RLN90289.1 - 7.5e-14 51.8 0.0 1.2e-07 31.9 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RLN90289.1 - 7.5e-11 42.1 0.0 1.4e-05 25.2 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RLN90289.1 - 6.1e-10 39.4 0.0 0.0011 19.3 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN90289.1 - 2.6e-05 24.4 0.0 0.11 12.8 0.0 2.7 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN90289.1 - 3.2e-05 23.9 0.0 0.00016 21.6 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain RSN1_7TM PF02714.15 RLN90291.1 - 1.8e-07 30.8 8.9 1.8e-07 30.8 8.9 2.2 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 RLN90291.1 - 1.3e-06 28.8 0.7 2.7e-06 27.7 0.7 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 RLN90291.1 - 0.0061 15.5 2.8 0.0066 15.3 0.1 2.4 3 0 0 3 3 3 1 Calcium-activated chloride channel Comm PF15957.5 RLN90291.1 - 0.061 13.7 0.4 0.28 11.5 0.4 2.2 1 0 0 1 1 1 0 Commissureless CCER1 PF15482.6 RLN90291.1 - 2.5 7.9 6.8 0.61 9.9 2.6 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing glutamate-rich protein family 1 BT1 PF03092.16 RLN90292.1 - 4.2e-17 61.6 15.3 2.5e-12 45.8 0.7 3.2 3 0 0 3 3 3 3 BT1 family PUCC PF03209.15 RLN90292.1 - 0.0026 16.8 0.2 0.0026 16.8 0.2 3.1 3 0 0 3 3 3 1 PUCC protein Pkinase PF00069.25 RLN90293.1 - 3.1e-51 174.3 0.0 4.1e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90293.1 - 7.4e-50 169.6 0.0 9.7e-50 169.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CD34_antigen PF06365.12 RLN90293.1 - 0.0017 18.0 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family Pkinase_fungal PF17667.1 RLN90293.1 - 0.0035 16.2 0.0 0.0051 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN90293.1 - 0.0035 17.3 0.1 0.064 13.2 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family EphA2_TM PF14575.6 RLN90293.1 - 0.0071 17.2 0.1 0.051 14.4 0.0 2.1 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Haspin_kinase PF12330.8 RLN90293.1 - 0.0082 15.1 0.0 0.023 13.7 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain G6B PF15096.6 RLN90293.1 - 0.026 14.3 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 G6B family TMEM154 PF15102.6 RLN90293.1 - 0.2 11.6 0.1 0.49 10.3 0.0 1.6 2 0 0 2 2 2 0 TMEM154 protein family LSR PF05624.14 RLN90293.1 - 1.7 8.7 4.6 4.2 7.5 4.6 1.6 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) AA_permease_C PF13906.6 RLN90294.1 - 2e-15 56.6 0.3 2e-15 56.6 0.3 3.1 4 1 0 4 4 4 1 C-terminus of AA_permease DUF2339 PF10101.9 RLN90294.1 - 0.0056 15.3 11.0 0.0069 15.0 11.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) DUF1275 PF06912.11 RLN90294.1 - 0.12 12.3 7.6 0.14 12.1 7.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1275) DUF1614 PF07758.11 RLN90294.1 - 0.17 11.9 6.0 0.28 11.2 5.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1614) CRPA PF05745.11 RLN90294.1 - 0.34 10.9 4.2 0.42 10.6 3.5 1.5 1 1 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF2070 PF09843.9 RLN90294.1 - 1.7 6.8 11.6 2 6.6 11.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Claudin_2 PF13903.6 RLN90294.1 - 4.7 6.9 11.2 0.055 13.2 2.5 2.0 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Sec20 PF03908.13 RLN90295.1 - 0.19 11.6 0.1 0.54 10.2 0.0 1.7 2 0 0 2 2 2 0 Sec20 DUF1084 PF06454.11 RLN90295.1 - 0.24 10.8 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1084) Glyoxalase PF00903.25 RLN90296.1 - 0.00063 19.9 0.0 0.0015 18.7 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 RLN90296.1 - 0.17 12.7 0.0 0.28 12.0 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain PDZ_6 PF17820.1 RLN90297.1 - 4e-07 29.8 1.2 0.0041 16.9 0.1 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 RLN90297.1 - 0.0016 18.8 0.0 0.036 14.4 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Fascin PF06268.13 RLN90297.1 - 0.029 14.6 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 Fascin domain zf-C3HC4_3 PF13920.6 RLN90298.1 - 1e-14 54.1 10.0 2.3e-14 53.0 10.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 RLN90298.1 - 1.2e-13 51.5 0.0 1.5e-07 31.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN90298.1 - 1.4e-13 50.7 0.9 2.5e-11 43.6 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN90298.1 - 6.8e-12 45.7 0.1 5.3e-11 42.8 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN90298.1 - 7e-12 44.5 0.2 0.00024 21.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 RLN90298.1 - 4.2e-10 39.6 1.3 0.00061 20.1 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat zf-RING_2 PF13639.6 RLN90298.1 - 7.7e-07 29.3 10.0 7.7e-07 29.3 10.0 1.8 2 0 0 2 2 1 1 Ring finger domain UIM PF02809.20 RLN90298.1 - 1e-05 25.1 1.0 2.6e-05 23.8 1.0 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif Prok-RING_4 PF14447.6 RLN90298.1 - 0.00012 21.9 11.2 0.00028 20.7 11.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 RLN90298.1 - 0.00084 19.1 11.5 0.0019 18.0 11.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN90298.1 - 0.013 15.5 10.5 0.03 14.3 10.5 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 RLN90298.1 - 0.18 11.6 8.6 0.56 10.0 8.6 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 RLN90298.1 - 1.2 9.3 9.4 4 7.7 9.5 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Glyco_transf_28 PF03033.20 RLN90299.1 - 1.7e-16 60.5 0.1 8.7e-15 55.0 0.1 3.1 3 1 0 3 3 3 1 Glycosyltransferase family 28 N-terminal domain Jiv90 PF14901.6 RLN90299.1 - 0.037 14.2 0.4 0.078 13.1 0.4 1.5 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone Ank_4 PF13637.6 RLN90301.1 - 1.2e-37 127.8 12.5 2e-08 34.6 0.2 8.8 5 2 4 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN90301.1 - 7e-35 118.6 21.1 1.8e-08 34.5 2.0 7.6 5 2 2 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN90301.1 - 3.1e-32 111.0 12.2 4e-12 46.6 0.3 5.5 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN90301.1 - 1.2e-28 95.9 13.2 0.00032 20.9 0.1 10.4 10 1 0 10 10 10 5 Ankyrin repeat Ank PF00023.30 RLN90301.1 - 3.1e-26 90.6 19.3 8.5e-05 22.8 0.4 9.0 9 0 0 9 9 9 6 Ankyrin repeat Tmemb_185A PF10269.9 RLN90301.1 - 1e-11 45.0 4.0 1e-11 45.0 4.0 2.2 1 1 1 2 2 2 1 Transmembrane Fragile-X-F protein ZYG-11_interact PF05884.12 RLN90301.1 - 0.068 12.6 1.2 0.17 11.3 1.2 1.6 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF805 PF05656.14 RLN90301.1 - 8 6.9 9.5 2.7 8.4 5.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF805) CwfJ_C_1 PF04677.15 RLN90302.1 - 1.2e-30 105.9 0.0 2.3e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 RLN90302.1 - 2.2e-08 34.9 0.0 4.5e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DZR PF12773.7 RLN90303.1 - 0.0014 18.6 1.8 0.32 11.1 0.2 3.0 3 0 0 3 3 3 2 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 RLN90303.1 - 0.032 14.1 2.2 0.23 11.4 0.1 2.9 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Vps36-NZF-N PF16988.5 RLN90303.1 - 0.13 11.7 1.4 0.24 10.8 0.5 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain HalOD2 PF18547.1 RLN90303.1 - 0.21 11.5 5.3 28 4.7 0.3 3.6 3 0 0 3 3 3 0 Halobacterial output domain 2 zf-RanBP PF00641.18 RLN90303.1 - 1.5 8.2 6.1 0.13 11.6 0.8 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others AATase PF07247.12 RLN90305.1 - 1.6e-09 36.9 0.0 2.3e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase AATase PF07247.12 RLN90307.1 - 1.5e-05 23.7 0.0 2.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Alcohol acetyltransferase AATase PF07247.12 RLN90308.1 - 0.00013 20.6 0.0 0.00061 18.5 0.0 1.8 1 1 0 1 1 1 1 Alcohol acetyltransferase DUF5542 PF17696.1 RLN90309.1 - 1.8 8.7 4.7 8.8 6.5 0.8 3.6 2 0 0 2 2 2 0 Family of unknown function (DUF5542) Mito_carr PF00153.27 RLN90310.1 - 2.5e-63 210.0 0.3 1.2e-20 73.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 RLN90310.1 - 9.5e-13 48.4 2.5 5.8e-08 33.1 0.1 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN90310.1 - 6.3e-07 28.8 8.5 0.00014 21.5 0.1 4.2 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 RLN90310.1 - 1e-06 27.8 6.6 0.0018 17.7 0.1 4.7 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 RLN90310.1 - 4.2e-06 26.5 0.5 0.084 12.7 0.0 3.9 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN90310.1 - 0.0061 16.0 0.6 0.0061 16.0 0.6 3.2 4 0 0 4 4 4 1 EF hand Dockerin_1 PF00404.18 RLN90310.1 - 0.18 12.0 0.6 0.53 10.5 0.6 1.8 1 0 0 1 1 1 0 Dockerin type I domain ATP-synt PF00231.19 RLN90311.1 - 7.9e-26 91.4 3.3 8.5e-26 91.3 3.3 1.0 1 0 0 1 1 1 1 ATP synthase Glyco_transf_22 PF03901.17 RLN90312.1 - 2.2e-52 178.7 14.5 2.8e-52 178.3 14.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family FYVE_2 PF02318.16 RLN90314.1 - 0.00024 21.3 3.6 0.0006 20.0 3.6 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger zf-C3HC4 PF00097.25 RLN90314.1 - 4.9 7.1 8.9 10 6.1 6.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 RLN90316.1 - 0.011 16.0 4.7 0.023 14.9 4.7 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger DZR PF12773.7 RLN90316.1 - 0.024 14.7 7.8 1.8 8.7 3.5 2.4 1 1 1 2 2 2 0 Double zinc ribbon Zn_Tnp_IS91 PF14319.6 RLN90316.1 - 0.25 11.4 3.8 0.12 12.4 0.5 2.0 2 0 0 2 2 2 0 Transposase zinc-binding domain CENP-B_dimeris PF09026.10 RLN90318.1 - 0.022 15.2 13.3 0.027 14.8 13.3 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 RLN90318.1 - 0.19 9.9 5.9 0.18 10.0 5.9 1.0 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 RLN90318.1 - 0.3 10.7 2.5 0.3 10.8 2.5 1.2 1 0 0 1 1 1 0 FAM176 family BUD22 PF09073.10 RLN90318.1 - 0.37 10.1 12.1 0.39 10.0 12.1 1.0 1 0 0 1 1 1 0 BUD22 TRAP_alpha PF03896.16 RLN90318.1 - 1.7 7.8 4.2 1.7 7.8 4.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 RLN90318.1 - 2.1 7.6 9.9 2.4 7.4 9.9 1.1 1 0 0 1 1 1 0 NOA36 protein Astro_capsid_p PF12226.8 RLN90318.1 - 2.5 7.2 9.8 2.9 7.0 9.8 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein EBV-NA3 PF05009.12 RLN90318.1 - 2.5 7.5 5.3 2.8 7.4 5.3 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) YL1 PF05764.13 RLN90318.1 - 3.8 7.5 12.0 4.4 7.4 12.0 1.0 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 RLN90318.1 - 4.1 5.6 7.8 4.1 5.6 7.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 RLN90318.1 - 6.5 4.7 12.2 7.2 4.6 12.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi Pkinase PF00069.25 RLN90319.1 - 6.3e-46 156.9 0.0 7.9e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90319.1 - 5.8e-32 111.0 0.0 7.3e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN90319.1 - 0.00024 20.0 0.0 0.00048 19.0 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 RLN90319.1 - 0.0064 15.8 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN90319.1 - 0.023 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 RLN90320.1 - 4.1e-58 196.8 0.0 9.7e-58 195.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90320.1 - 9.9e-19 67.6 0.6 1.3e-17 63.9 0.6 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN90320.1 - 4.1e-05 23.6 0.4 7.3e-05 22.8 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN90320.1 - 0.0029 16.4 0.5 0.015 14.1 0.1 1.9 1 1 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 RLN90320.1 - 0.015 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 RLN90320.1 - 0.083 11.8 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1849 PF08904.11 RLN90320.1 - 0.18 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1849) Pkinase PF00069.25 RLN90322.1 - 1.4e-50 172.2 0.0 4e-40 137.9 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90322.1 - 2.1e-16 60.0 0.0 3e-12 46.4 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase PDZ PF00595.24 RLN90322.1 - 2e-11 44.1 0.0 0.21 12.0 0.0 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 RLN90322.1 - 5.9e-11 42.1 0.2 0.035 14.0 0.0 4.4 4 0 0 4 4 4 4 PDZ domain Kinase-like PF14531.6 RLN90322.1 - 0.00055 19.3 0.0 0.045 13.1 0.0 2.2 1 1 1 2 2 2 2 Kinase-like PDZ_2 PF13180.6 RLN90322.1 - 0.0009 19.5 0.3 9.6 6.6 0.1 4.0 4 0 0 4 4 4 1 PDZ domain HTH_Tnp_Tc5 PF03221.16 RLN90323.1 - 1.6e-07 31.2 0.1 2.6e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain FAM183 PF14886.6 RLN90324.1 - 4.5e-06 27.3 1.1 1e-05 26.2 1.1 1.5 1 1 0 1 1 1 1 FAM183A and FAM183B related Peptidase_S28 PF05577.12 RLN90326.1 - 6.6e-77 259.1 0.0 7.8e-77 258.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 RLN90326.1 - 3.7e-06 25.9 0.0 5.6e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 RLN90326.1 - 6.9e-05 22.2 0.1 0.00011 21.6 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN90326.1 - 0.00047 19.9 0.5 0.0011 18.7 0.5 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2920 PF11144.8 RLN90326.1 - 0.0016 17.7 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Peptidase_S9 PF00326.21 RLN90326.1 - 0.06 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 RLN90326.1 - 0.52 10.9 10.5 0.57 10.8 6.0 2.6 2 1 0 2 2 2 0 Alpha/beta hydrolase family NMD3 PF04981.13 RLN90327.1 - 8.3e-39 133.5 0.1 1.1e-38 133.1 0.1 1.2 1 0 0 1 1 1 1 NMD3 family NMD3 PF04981.13 RLN90328.1 - 1.6e-71 240.7 7.6 2.4e-71 240.0 7.6 1.3 1 0 0 1 1 1 1 NMD3 family CxC5 PF18718.1 RLN90328.1 - 0.0066 16.5 0.5 0.0066 16.5 0.5 1.7 2 0 0 2 2 2 1 CxC5 like cysteine cluster associated with KDZ transposases Myc_N PF01056.18 RLN90328.1 - 0.013 15.4 2.4 0.027 14.4 2.4 1.5 1 0 0 1 1 1 0 Myc amino-terminal region RNA_pol_3_Rpc31 PF11705.8 RLN90328.1 - 0.93 9.7 9.8 1.5 9.0 9.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FYDLN_acid PF09538.10 RLN90328.1 - 9.4 7.0 10.2 75 4.1 7.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PRCC PF10253.9 RLN90329.1 - 1.9e-06 28.8 22.5 1.9e-06 28.8 22.5 2.8 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting DUF2786 PF10979.8 RLN90330.1 - 1.2 9.1 3.7 5.8 6.9 3.7 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) D-ser_dehydrat PF14031.6 RLN90331.1 - 8.7e-20 71.2 0.0 1.5e-19 70.5 0.0 1.4 1 1 0 1 1 1 1 Putative serine dehydratase domain DUF5530 PF17670.1 RLN90331.1 - 0.035 13.9 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5530) NTPase_1 PF03266.15 RLN90331.1 - 0.19 11.6 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 NTPase 2OG-FeII_Oxy_3 PF13640.6 RLN90332.1 - 2.5e-18 66.7 0.0 5.4e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 RLN90332.1 - 1.3e-09 38.5 0.0 4.6e-09 36.8 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Oxygenase-NA PF09859.9 RLN90332.1 - 0.0079 15.7 0.7 1.4 8.4 0.0 2.3 2 0 0 2 2 2 2 Oxygenase, catalysing oxidative methylation of damaged DNA PhyH PF05721.13 RLN90332.1 - 0.053 13.8 0.1 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) ETF PF01012.21 RLN90333.1 - 6.1e-14 52.3 6.0 7e-14 52.1 6.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DAD PF02109.16 RLN90334.1 - 1e-34 119.1 3.1 6.9e-34 116.4 3.1 1.9 1 1 0 1 1 1 1 DAD family Prefoldin_2 PF01920.20 RLN90335.1 - 5.1e-14 52.1 9.3 5.1e-14 52.1 9.3 1.9 2 0 0 2 2 2 1 Prefoldin subunit TPR_2 PF07719.17 RLN90335.1 - 6.1e-06 26.0 3.3 0.053 13.6 1.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN90335.1 - 1e-05 25.1 2.5 0.044 13.6 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN90335.1 - 1.4e-05 25.0 3.8 0.0098 16.0 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN90335.1 - 0.00015 22.2 1.7 0.00015 22.2 1.7 2.2 2 1 0 2 2 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN90335.1 - 0.0034 17.3 0.4 0.02 14.9 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN90335.1 - 0.0081 16.5 0.6 0.024 15.0 0.1 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat End3 PF12761.7 RLN90335.1 - 0.0097 16.1 11.0 0.06 13.5 10.6 1.9 1 1 1 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 Osmo_CC PF08946.10 RLN90335.1 - 0.012 15.8 3.2 0.72 10.1 0.6 2.9 2 0 0 2 2 2 0 Osmosensory transporter coiled coil TPR_14 PF13428.6 RLN90335.1 - 0.014 16.2 3.9 0.75 10.8 0.3 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat CHDCT2 PF08074.11 RLN90335.1 - 0.016 15.4 1.8 0.04 14.1 0.2 2.0 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain BCL9 PF11502.8 RLN90335.1 - 0.026 14.3 0.3 0.27 11.1 0.2 2.4 2 0 0 2 2 2 0 B-cell lymphoma 9 protein Jnk-SapK_ap_N PF09744.9 RLN90335.1 - 0.064 13.5 13.8 0.65 10.2 0.8 2.9 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 CCDC-167 PF15188.6 RLN90335.1 - 0.078 13.3 6.2 0.27 11.6 5.3 2.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 TPR_6 PF13174.6 RLN90335.1 - 0.13 13.0 1.6 7.3 7.5 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN90335.1 - 0.31 11.0 9.7 1.5 8.8 0.3 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat Fib_alpha PF08702.10 RLN90335.1 - 0.35 11.0 6.4 0.18 12.0 4.1 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FUSC PF04632.12 RLN90335.1 - 0.36 9.3 4.2 0.41 9.1 4.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA_13 PF13166.6 RLN90335.1 - 0.36 9.4 10.8 0.12 11.0 1.5 2.2 1 1 1 2 2 2 0 AAA domain NPV_P10 PF05531.12 RLN90335.1 - 0.41 11.2 2.0 20 5.7 0.0 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.13 RLN90335.1 - 0.44 11.3 5.5 5.5 7.8 0.3 3.2 1 1 1 2 2 2 0 Occludin homology domain DUF5082 PF16888.5 RLN90335.1 - 0.54 10.6 8.7 2 8.7 2.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) FTA4 PF13093.6 RLN90335.1 - 0.54 10.1 11.4 0.39 10.6 6.7 2.1 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Sec34 PF04136.15 RLN90335.1 - 0.91 9.4 6.9 5.6 6.8 2.8 2.8 2 1 1 3 3 3 0 Sec34-like family KASH_CCD PF14662.6 RLN90335.1 - 1.4 8.7 12.0 0.17 11.7 3.9 2.3 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH V_ATPase_I PF01496.19 RLN90335.1 - 1.4 6.7 6.6 0.71 7.7 4.7 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 RLN90335.1 - 1.4 7.7 15.8 6.8 5.5 0.3 2.6 1 1 2 3 3 3 0 Spc7 kinetochore protein TPR_4 PF07721.14 RLN90335.1 - 1.6 9.6 6.1 2.3 9.1 0.5 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN90335.1 - 1.6 9.1 7.4 8.1 6.8 4.7 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TMF_TATA_bd PF12325.8 RLN90335.1 - 1.7 8.9 12.9 2.3 8.5 2.1 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.9 RLN90335.1 - 2.4 8.5 12.3 1.2 9.5 0.5 3.1 2 2 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Med9 PF07544.13 RLN90335.1 - 2.6 8.2 7.8 0.46 10.6 0.2 2.9 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF3450 PF11932.8 RLN90335.1 - 3.4 6.9 14.4 1.5 8.1 3.5 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) YabA PF06156.13 RLN90335.1 - 5 7.8 6.9 2.2e+02 2.6 6.1 3.0 2 1 0 2 2 2 0 Initiation control protein YabA TMPIT PF07851.13 RLN90335.1 - 7.3 5.7 6.9 2.9 7.1 3.5 1.8 2 0 0 2 2 2 0 TMPIT-like protein EMC1_C PF07774.13 RLN90336.1 - 4.6e-67 225.8 0.0 7.3e-67 225.2 0.0 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 RLN90336.1 - 1.3e-14 54.4 12.6 2.3e-11 43.7 3.1 3.7 4 0 0 4 4 4 3 PQQ-like domain AAA_12 PF13087.6 RLN90337.1 - 1.9e-36 125.6 0.0 6.2e-36 123.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 RLN90337.1 - 4.2e-20 72.6 0.7 6.9e-20 71.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RLN90337.1 - 1.1e-08 35.0 0.5 0.00019 21.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 RLN90337.1 - 1.5e-06 28.6 0.1 1.6e-05 25.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 RLN90337.1 - 0.0074 15.6 0.0 2.1 7.5 0.0 2.7 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) HALZ PF02183.18 RLN90338.1 - 0.0038 17.4 2.2 0.0065 16.7 2.2 1.3 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_1 PF00170.21 RLN90338.1 - 0.009 16.1 2.7 0.017 15.2 2.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor DivIC PF04977.15 RLN90338.1 - 0.016 15.0 2.3 0.024 14.4 2.3 1.3 1 0 0 1 1 1 0 Septum formation initiator FlaC_arch PF05377.11 RLN90338.1 - 0.028 14.8 0.6 0.1 13.0 0.1 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 RLN90338.1 - 0.044 14.2 8.0 0.067 13.6 8.0 1.2 1 0 0 1 1 1 0 Cell division protein ZapB DUF2570 PF10828.8 RLN90338.1 - 0.08 12.8 1.0 0.14 12.0 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Oxysterol_BP PF01237.18 RLN90339.1 - 2e-44 152.0 0.2 8.3e-34 117.0 0.0 2.6 2 1 1 3 3 3 2 Oxysterol-binding protein START PF01852.19 RLN90339.1 - 6.6e-15 55.1 0.1 4.8e-09 35.9 0.1 2.4 2 0 0 2 2 2 2 START domain PH PF00169.29 RLN90339.1 - 3.4e-12 46.8 0.0 6.6e-11 42.7 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 RLN90339.1 - 0.00027 21.3 0.1 0.00065 20.1 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 RLN90339.1 - 0.091 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Podoplanin PF05808.11 RLN90342.1 - 0.0014 18.8 0.2 0.0026 17.9 0.2 1.5 1 0 0 1 1 1 1 Podoplanin EphA2_TM PF14575.6 RLN90342.1 - 0.01 16.7 0.0 0.04 14.8 0.0 1.9 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 RLN90342.1 - 0.026 13.9 1.2 0.075 12.5 1.2 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 RLN90342.1 - 0.058 13.2 2.4 0.15 11.9 2.4 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pkinase_Tyr PF07714.17 RLN90342.1 - 0.082 12.2 0.1 0.15 11.3 0.0 1.4 2 0 0 2 2 2 0 Protein tyrosine kinase Rax2 PF12768.7 RLN90342.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Protocadherin PF08374.11 RLN90342.1 - 0.18 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Protocadherin DAP10 PF07213.11 RLN90342.1 - 0.26 11.3 2.4 0.23 11.4 0.4 1.9 2 0 0 2 2 2 0 DAP10 membrane protein Pkinase PF00069.25 RLN90343.1 - 7.6e-51 173.0 0.0 1.1e-50 172.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90343.1 - 1.6e-44 152.2 0.0 2.2e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RLN90343.1 - 0.15 11.0 0.1 0.46 9.4 0.1 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 RLN90343.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Myosin_head PF00063.21 RLN90346.1 - 1.7e-20 72.8 6.9 5.9e-12 44.6 0.7 3.0 2 1 1 3 3 3 3 Myosin head (motor domain) Pkinase_Tyr PF07714.17 RLN90349.1 - 1.9e-51 174.8 0.0 2.4e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN90349.1 - 2.3e-50 171.4 0.0 3.1e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 RLN90349.1 - 0.0097 14.7 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 RLN90349.1 - 0.025 13.5 0.0 0.37 9.7 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 RLN90349.1 - 0.062 12.7 0.1 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN90349.1 - 0.088 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ion_trans PF00520.31 RLN90350.1 - 1.7e-13 50.4 4.7 2.7e-13 49.7 4.7 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RLN90350.1 - 6.6e-11 42.0 4.7 6.6e-11 42.0 4.7 2.1 2 0 0 2 2 2 1 Ion channel DUF3228 PF11539.8 RLN90351.1 - 5.9e-85 283.7 0.0 7e-85 283.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) DnaJ PF00226.31 RLN90352.1 - 9.5e-05 22.4 0.0 0.00021 21.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain GYF_2 PF14237.6 RLN90352.1 - 0.024 14.5 0.0 0.063 13.1 0.0 1.7 1 0 0 1 1 1 0 GYF domain 2 VIR_N PF15912.5 RLN90352.1 - 0.37 10.4 4.2 0.53 9.8 4.2 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Pkinase_Tyr PF07714.17 RLN90353.1 - 7.4e-52 176.2 0.0 9.2e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN90353.1 - 6.1e-50 170.0 0.0 8.3e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 RLN90353.1 - 0.0055 15.7 0.0 0.21 10.5 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 RLN90353.1 - 0.0071 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase TrbC PF04956.13 RLN90353.1 - 0.0091 16.2 0.1 0.019 15.2 0.1 1.5 1 0 0 1 1 1 1 TrbC/VIRB2 family EphA2_TM PF14575.6 RLN90353.1 - 0.012 16.4 0.0 0.024 15.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 RLN90353.1 - 0.03 13.7 0.6 0.064 12.7 0.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4381 PF14316.6 RLN90353.1 - 0.035 14.3 0.2 0.35 11.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) DUF2681 PF10883.8 RLN90353.1 - 0.053 13.9 1.5 0.066 13.6 0.1 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF2681) TMEM154 PF15102.6 RLN90353.1 - 0.054 13.4 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family APH PF01636.23 RLN90353.1 - 0.055 13.4 0.1 0.35 10.7 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF5385 PF17359.2 RLN90353.1 - 0.056 13.0 0.8 0.085 12.4 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5385) DUF4448 PF14610.6 RLN90353.1 - 0.057 13.2 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Cu-binding_MopE PF11617.8 RLN90353.1 - 0.061 13.5 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Putative metal-binding motif MAP17 PF15807.5 RLN90353.1 - 0.062 13.5 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF2207 PF09972.9 RLN90353.1 - 0.064 12.0 0.0 0.091 11.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Insulin_TMD PF17870.1 RLN90353.1 - 0.069 13.2 1.3 0.15 12.1 1.3 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Kdo PF06293.14 RLN90353.1 - 0.074 12.4 0.1 0.34 10.2 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family LPG_synthase_TM PF03706.13 RLN90353.1 - 0.075 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region DcuC PF03606.15 RLN90353.1 - 0.089 11.2 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Peptidase_M56 PF05569.11 RLN90353.1 - 0.09 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 ASFV_J13L PF05568.11 RLN90353.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein ADH_N PF08240.12 RLN90355.1 - 1.7e-27 95.4 0.5 1.7e-27 95.4 0.5 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN90355.1 - 3.5e-24 85.2 0.6 5.3e-24 84.6 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN90355.1 - 9.5e-05 23.5 0.2 0.00016 22.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 RLN90355.1 - 0.021 14.3 0.1 0.037 13.5 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Viral_Beta_CD PF04530.12 RLN90355.1 - 0.047 14.0 0.1 0.047 14.0 0.1 2.0 3 0 0 3 3 3 0 Viral Beta C/D like family Epimerase PF01370.21 RLN90355.1 - 0.11 12.0 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RRM_1 PF00076.22 RLN90356.1 - 2e-16 59.5 0.0 3.6e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RLN90356.1 - 2.4e-08 33.6 0.0 2.7e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 RLN90356.1 - 0.075 13.3 0.0 0.32 11.2 0.0 1.9 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF3791 PF12668.7 RLN90356.1 - 0.12 12.4 0.1 3.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) Ank_2 PF12796.7 RLN90357.1 - 9.9e-22 77.3 5.5 7.8e-08 32.8 0.2 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN90357.1 - 1.1e-19 70.2 7.2 0.023 15.0 0.0 8.5 5 1 3 8 8 8 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN90357.1 - 1.5e-16 60.5 9.4 2.5e-06 27.9 0.2 6.5 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN90357.1 - 7.5e-14 50.5 4.6 1.7 9.4 0.0 8.6 9 0 0 9 9 9 3 Ankyrin repeat Ank PF00023.30 RLN90357.1 - 1.6e-05 25.1 1.0 20 5.8 0.0 6.2 2 1 1 3 3 3 1 Ankyrin repeat DUF5049 PF16468.5 RLN90357.1 - 0.0013 18.6 0.2 13 5.8 0.0 4.7 2 1 3 5 5 5 1 Domain of unknown function (DUF5049) VHL_C PF17211.3 RLN90357.1 - 0.033 14.2 0.2 17 5.5 0.0 4.1 5 1 0 5 5 5 0 VHL box domain DUF249 PF03158.13 RLN90357.1 - 0.06 13.1 0.1 4.9 6.8 0.0 3.0 2 1 1 3 3 3 0 Multigene family 530 protein BT1 PF03092.16 RLN90358.1 - 4.1e-17 61.6 18.3 9.2e-09 34.1 0.1 3.7 3 1 1 4 4 4 3 BT1 family Mobilization_B PF17511.2 RLN90358.1 - 7.6 6.9 7.5 24 5.3 0.2 2.6 2 0 0 2 2 2 0 Mobilization protein B ADH_zinc_N_2 PF13602.6 RLN90359.1 - 4.7e-18 66.5 0.0 4.6e-17 63.3 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 RLN90359.1 - 4.4e-12 46.1 0.0 1e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN90359.1 - 5.2e-09 36.0 0.0 2.9e-08 33.6 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_16 PF10294.9 RLN90359.1 - 0.01 15.6 0.3 0.02 14.7 0.0 1.6 2 0 0 2 2 2 0 Lysine methyltransferase Eno-Rase_NADH_b PF12242.8 RLN90359.1 - 0.011 15.5 0.3 0.023 14.5 0.3 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HTH_Tnp_Tc5 PF03221.16 RLN90360.1 - 0.00047 20.1 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 RLN90360.1 - 0.032 14.0 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease ROK PF00480.20 RLN90362.1 - 2.3e-52 178.3 0.0 2.9e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.16 RLN90362.1 - 0.00017 20.7 1.0 0.098 11.6 1.1 2.9 3 0 0 3 3 3 2 Glucokinase CPDase PF07823.11 RLN90362.1 - 0.21 11.3 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein Methyltransf_16 PF10294.9 RLN90363.1 - 6.5e-20 71.6 0.0 1.1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 RLN90363.1 - 0.0031 18.2 0.1 0.012 16.3 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN90363.1 - 0.0033 17.0 0.1 0.0052 16.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 RLN90363.1 - 0.021 14.7 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 RLN90363.1 - 0.2 11.3 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Shisa PF13908.6 RLN90365.1 - 0.012 15.9 0.4 0.038 14.2 0.0 1.9 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator SurA_N_3 PF13624.6 RLN90365.1 - 0.028 14.2 0.1 0.028 14.2 0.1 2.3 2 1 1 3 3 3 0 SurA N-terminal domain DUF4448 PF14610.6 RLN90365.1 - 0.046 13.5 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Tombus_movement PF05318.12 RLN90365.1 - 0.15 12.9 5.1 0.14 13.0 3.5 1.8 2 0 0 2 2 2 0 Tombusvirus movement protein Ndc1_Nup PF09531.10 RLN90365.1 - 0.32 9.7 2.5 0.38 9.4 2.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DcuA_DcuB PF03605.14 RLN90365.1 - 0.38 9.6 2.0 0.4 9.5 0.3 1.7 2 0 0 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter AP3D1 PF06375.11 RLN90365.1 - 0.91 9.7 15.0 0.67 10.2 13.7 1.4 1 1 0 1 1 1 0 AP-3 complex subunit delta-1 DUF3464 PF11947.8 RLN90365.1 - 2 8.1 4.6 0.5 10.1 1.2 1.7 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 PKK PF12474.8 RLN90365.1 - 2.4 8.3 16.5 0.49 10.5 12.9 1.5 1 1 0 1 1 1 0 Polo kinase kinase TRIQK PF15168.6 RLN90365.1 - 3.1 7.8 6.1 0.19 11.7 0.8 1.7 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family NACHT_N PF17100.5 RLN90365.1 - 4.5 7.1 8.6 0.89 9.4 4.5 1.8 1 1 1 2 2 2 0 N-terminal domain of NWD NACHT-NTPase V-SNARE PF05008.15 RLN90366.1 - 1.5e-07 31.7 3.8 1e-06 29.0 1.1 2.2 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 RLN90366.1 - 4.2e-06 26.6 0.7 0.0022 17.9 0.0 2.5 2 1 2 4 4 4 3 Sec20 DUF4337 PF14235.6 RLN90366.1 - 0.13 12.4 1.3 0.27 11.3 1.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) UPF0524 PF15823.5 RLN90367.1 - 0.022 14.2 0.1 0.033 13.6 0.1 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 Peptidase_M22 PF00814.25 RLN90368.1 - 1e-44 153.3 0.0 3.3e-28 99.2 0.0 2.9 2 1 0 2 2 2 2 Glycoprotease family KIAA1430 PF13879.6 RLN90370.1 - 0.00022 21.9 0.1 0.00022 21.9 0.1 3.0 2 2 0 2 2 2 1 KIAA1430 homologue Chalcone_2 PF16035.5 RLN90370.1 - 0.028 14.2 0.6 0.052 13.3 0.6 1.4 1 0 0 1 1 1 0 Chalcone isomerase like Vps4_C PF09336.10 RLN90370.1 - 0.052 13.5 0.3 0.14 12.2 0.3 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain TetR_C_18 PF17923.1 RLN90370.1 - 0.11 13.0 0.1 0.29 11.7 0.1 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Mg_trans_NIPA PF05653.14 RLN90371.1 - 3.2e-10 39.6 8.6 7.8e-08 31.8 0.3 2.6 2 1 1 3 3 3 2 Magnesium transporter NIPA EamA PF00892.20 RLN90371.1 - 0.035 14.3 18.0 0.064 13.4 5.3 3.2 2 1 0 2 2 2 0 EamA-like transporter family Macoilin PF09726.9 RLN90372.1 - 0.2 10.2 4.9 0.24 9.9 4.9 1.1 1 0 0 1 1 1 0 Macoilin family LigB PF02900.18 RLN90373.1 - 1.4e-23 83.4 0.0 1.5e-23 83.2 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Retrotrans_gag PF03732.17 RLN90374.1 - 0.0014 18.8 0.1 0.0047 17.2 0.0 1.8 1 1 1 2 2 2 1 Retrotransposon gag protein Ras PF00071.22 RLN90375.1 - 8.6e-35 119.7 0.0 1.2e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Smg4_UPF3 PF03467.15 RLN90375.1 - 2.6e-26 92.7 1.5 3.4e-26 92.3 0.0 1.9 2 0 0 2 2 2 1 Smg-4/UPF3 family Roc PF08477.13 RLN90375.1 - 5.1e-25 88.0 0.0 8.5e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN90375.1 - 1.9e-08 33.9 0.0 3.1e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RLN90375.1 - 0.004 16.5 0.1 0.0058 16.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RLN90375.1 - 0.024 14.7 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gly_transf_sug PF04488.15 RLN90376.1 - 7.4e-12 45.8 0.0 1.3e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 RLN90376.1 - 5.1e-05 22.8 0.0 7.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gb3_synth PF04572.12 RLN90376.1 - 0.043 14.0 0.1 0.11 12.7 0.0 1.7 2 0 0 2 2 2 0 Alpha 1,4-glycosyltransferase conserved region Flexi_CP_N PF08358.10 RLN90377.1 - 0.055 13.5 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Carlavirus coat HWE_HK PF07536.14 RLN90377.1 - 0.15 12.7 2.3 0.54 11.0 0.2 2.5 1 1 2 3 3 3 0 HWE histidine kinase FAM76 PF16046.5 RLN90377.1 - 0.51 9.7 15.6 0.23 10.8 1.7 2.2 2 0 0 2 2 2 0 FAM76 protein DUF1515 PF07439.11 RLN90377.1 - 1.3 9.1 7.5 0.23 11.5 1.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1515) DUF4061 PF13270.6 RLN90377.1 - 1.3 9.3 12.9 1.5 9.2 4.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4061) HalX PF08663.10 RLN90377.1 - 2.7 8.4 13.1 2.9 8.3 2.2 3.5 2 2 1 3 3 3 0 HalX domain HIP1_clath_bdg PF16515.5 RLN90377.1 - 3 8.5 22.2 0.78 10.4 4.8 2.7 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 UPF0242 PF06785.11 RLN90377.1 - 3.4 7.7 22.0 2.2 8.4 6.5 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF883 PF05957.13 RLN90377.1 - 4 8.1 8.7 1.3 9.7 0.2 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) TMPIT PF07851.13 RLN90377.1 - 4.1 6.6 13.8 3.4 6.8 6.1 2.0 1 1 1 2 2 2 0 TMPIT-like protein STAT_alpha PF01017.20 RLN90377.1 - 5.8 6.8 16.6 0.39 10.6 3.2 2.1 1 1 1 2 2 2 0 STAT protein, all-alpha domain Sec2p PF06428.11 RLN90377.1 - 8.2 6.5 23.8 1.1 9.3 1.7 3.6 2 2 1 3 3 3 0 GDP/GTP exchange factor Sec2p AATF-Che1 PF13339.6 RLN90377.1 - 9.5 6.9 16.3 0.57 10.9 9.2 2.3 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Kinesin PF00225.23 RLN90378.1 - 1.4e-95 320.1 0.0 5.4e-95 318.1 0.0 2.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN90378.1 - 6.8e-45 152.6 0.0 3.2e-44 150.5 0.0 2.3 1 0 0 1 1 1 1 Microtubule binding YqaJ PF09588.10 RLN90380.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain WD40 PF00400.32 RLN90381.1 - 0.00017 22.3 1.5 0.00058 20.6 0.7 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN90381.1 - 0.012 15.9 0.1 0.017 15.4 0.1 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Tox-HDC PF15656.6 RLN90381.1 - 0.04 14.1 0.0 0.042 14.0 0.0 1.0 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature SesA PF17107.5 RLN90382.1 - 0.0056 16.9 0.0 0.0071 16.5 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Tox-ODYAM1 PF15642.6 RLN90382.1 - 0.04 12.9 0.0 0.047 12.7 0.0 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Spec3 PF15795.5 RLN90382.1 - 0.064 13.8 0.2 0.087 13.4 0.1 1.3 1 1 0 1 1 1 0 Ectodermal ciliogenesis protein Pkinase PF00069.25 RLN90383.1 - 2.1e-102 342.0 0.0 2.4e-39 135.3 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90383.1 - 4.3e-98 327.7 0.0 4.3e-40 137.6 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 RLN90383.1 - 1.3e-10 41.1 0.0 0.00014 21.2 0.0 3.3 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.14 RLN90383.1 - 3e-07 30.0 0.2 0.06 12.7 0.1 3.4 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN90383.1 - 1.2e-06 28.7 6.2 0.0056 16.6 0.1 4.3 3 1 0 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 RLN90383.1 - 1.9e-05 24.4 0.0 0.045 13.3 0.0 2.9 3 0 0 3 3 3 2 RIO1 family Seadorna_VP7 PF07387.11 RLN90383.1 - 0.053 12.6 0.5 6.3 5.8 0.1 2.3 2 0 0 2 2 2 0 Seadornavirus VP7 Pkinase_Tyr PF07714.17 RLN90384.1 - 5.8e-38 130.6 0.0 9.1e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN90384.1 - 1.3e-28 100.1 0.0 1.9e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90385.1 - 2.9e-41 141.5 0.0 5.4e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN90385.1 - 7.2e-35 120.6 0.0 1.9e-34 119.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain zinc_ribbon_15 PF17032.5 RLN90385.1 - 0.00036 21.2 0.6 0.00084 20.0 0.6 1.6 1 0 0 1 1 1 1 zinc-ribbon family DZR PF12773.7 RLN90385.1 - 0.00073 19.5 0.2 0.0017 18.4 0.2 1.5 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 RLN90385.1 - 0.0024 17.5 1.1 0.0049 16.5 1.1 1.5 1 0 0 1 1 1 1 zinc-ribbon domain APH PF01636.23 RLN90385.1 - 0.025 14.5 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-ribbon_3 PF13248.6 RLN90385.1 - 0.043 13.2 1.1 0.078 12.4 1.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain RIO1 PF01163.22 RLN90385.1 - 0.044 13.4 0.0 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 RIO1 family zf-NADH-PPase PF09297.11 RLN90385.1 - 0.32 10.7 1.7 0.72 9.6 0.1 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF5472 PF17566.2 RLN90385.1 - 0.44 10.5 2.4 5.1 7.1 0.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5472) Pkinase_Tyr PF07714.17 RLN90386.1 - 5e-42 144.0 0.0 8.1e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN90386.1 - 2.7e-32 112.2 0.0 4.8e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DZR PF12773.7 RLN90386.1 - 7.2e-09 35.5 6.7 1.7e-08 34.3 6.7 1.7 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 RLN90386.1 - 2.9e-08 34.3 2.7 0.0024 18.6 0.6 2.5 2 0 0 2 2 2 2 zinc-ribbon family zinc_ribbon_2 PF13240.6 RLN90386.1 - 7.5e-05 22.3 5.9 0.016 14.9 1.2 2.8 2 0 0 2 2 2 2 zinc-ribbon domain zf-ribbon_3 PF13248.6 RLN90386.1 - 0.0013 18.0 1.2 0.0013 18.0 1.2 2.8 3 0 0 3 3 3 1 zinc-ribbon domain UPF0547 PF10571.9 RLN90386.1 - 0.0055 16.8 12.0 0.0076 16.3 1.8 2.9 3 0 0 3 3 3 2 Uncharacterised protein family UPF0547 APH PF01636.23 RLN90386.1 - 0.072 13.0 2.8 0.24 11.3 0.0 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family zf-NADH-PPase PF09297.11 RLN90386.1 - 0.27 10.9 0.1 0.27 10.9 0.1 3.1 5 0 0 5 5 5 0 NADH pyrophosphatase zinc ribbon domain zf_UBZ PF18439.1 RLN90386.1 - 1.4 8.6 6.5 20 4.9 0.0 3.6 2 1 1 3 3 3 0 Ubiquitin-Binding Zinc Finger TF_Zn_Ribbon PF08271.12 RLN90386.1 - 2.2 7.9 6.6 6.4 6.4 1.5 2.9 2 0 0 2 2 2 0 TFIIB zinc-binding Pkinase_Tyr PF07714.17 RLN90387.1 - 1.4e-64 217.9 0.0 4.6e-37 127.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN90387.1 - 1.3e-60 205.0 0.0 7.6e-36 123.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 RLN90387.1 - 1.1e-06 28.8 1.3 0.028 14.4 0.0 2.6 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 RLN90387.1 - 1.8e-06 27.4 0.1 0.035 13.5 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN90387.1 - 3.6e-06 26.0 0.0 0.0011 17.8 0.0 2.4 3 0 0 3 3 3 2 Fungal protein kinase Kinase-like PF14531.6 RLN90387.1 - 2.4e-05 23.8 0.0 0.09 12.1 0.0 2.8 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.22 RLN90387.1 - 0.11 12.1 0.0 17 4.9 0.0 2.3 2 0 0 2 2 2 0 RIO1 family His_biosynth PF00977.21 RLN90389.1 - 4.7e-11 42.6 0.0 2.3e-09 37.1 0.0 2.1 2 0 0 2 2 2 2 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 RLN90389.1 - 0.18 11.1 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family SF3b10 PF07189.11 RLN90390.1 - 1e-34 118.4 0.0 1.7e-22 79.3 0.0 2.1 2 0 0 2 2 2 2 Splicing factor 3B subunit 10 (SF3b10) Ion_trans PF00520.31 RLN90391.1 - 0.079 12.2 1.2 0.11 11.6 1.2 1.1 1 0 0 1 1 1 0 Ion transport protein GPI2 PF06432.11 RLN90391.1 - 0.1 12.0 2.9 0.14 11.6 2.9 1.2 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase zf-C3HC4_3 PF13920.6 RLN90392.1 - 6e-11 42.0 10.0 6e-11 42.0 10.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN90392.1 - 8.4e-06 25.6 10.3 2.4e-05 24.1 10.3 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN90392.1 - 0.48 10.4 10.6 1 9.4 10.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Suf PF05843.14 RLN90392.1 - 1 9.3 7.4 0.1 12.6 2.3 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SPX PF03105.19 RLN90392.1 - 2.3 8.1 23.1 0.16 11.9 16.8 1.9 2 0 0 2 2 2 0 SPX domain zf-RING_2 PF13639.6 RLN90392.1 - 4.8 7.6 17.7 0.25 11.7 12.0 1.9 2 1 0 2 2 2 0 Ring finger domain WD40 PF00400.32 RLN90393.1 - 0.00079 20.2 0.0 0.084 13.8 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN90393.1 - 0.1 12.9 0.0 1.2 9.5 0.0 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Folate_carrier PF01770.18 RLN90394.1 - 0.32 9.7 0.5 0.44 9.2 0.5 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF572 PF04502.13 RLN90394.1 - 1.5 8.4 9.2 1.6 8.2 9.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_S46 PF10459.9 RLN90396.1 - 0.082 11.5 5.3 0.1 11.2 5.3 1.1 1 0 0 1 1 1 0 Peptidase S46 Mt_ATP-synt_B PF05405.14 RLN90396.1 - 0.095 12.3 2.0 0.16 11.6 2.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) CP12 PF02672.15 RLN90396.1 - 0.81 10.5 3.0 2.4 9.0 3.0 1.8 1 0 0 1 1 1 0 CP12 domain HSP70 PF00012.20 RLN90398.1 - 4.4e-46 157.3 0.2 6e-46 156.8 0.2 1.2 1 0 0 1 1 1 1 Hsp70 protein Gon7 PF08738.10 RLN90398.1 - 0.26 11.4 0.1 0.26 11.4 0.1 2.9 4 0 0 4 4 4 0 Gon7 family RPN6_N PF18055.1 RLN90399.1 - 2.4e-24 85.9 0.5 2.4e-24 85.9 0.5 3.2 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 RLN90399.1 - 1.5e-08 35.1 3.2 5.1e-08 33.4 0.4 2.8 3 0 0 3 3 3 1 PCI domain Rx_N PF18052.1 RLN90399.1 - 0.011 15.9 0.9 0.03 14.6 0.1 2.2 2 0 0 2 2 2 0 Rx N-terminal domain DUF410 PF04190.13 RLN90399.1 - 0.085 12.6 5.5 4.1 7.1 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF410) PDZ_6 PF17820.1 RLN90400.1 - 1.1e-08 34.8 0.1 2.9e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 RLN90400.1 - 5.2e-05 23.5 0.0 0.1 13.0 0.0 3.1 3 0 0 3 3 3 2 PDZ domain DUF1192 PF06698.11 RLN90401.1 - 0.027 14.5 0.5 0.3 11.1 0.0 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) AAA_6 PF12774.7 RLN90402.1 - 7.4e-154 511.6 0.0 2.5e-153 509.8 0.0 1.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN90402.1 - 1.9e-134 448.8 10.0 1.9e-134 448.8 10.0 2.4 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Dynein_AAA_lid PF17852.1 RLN90402.1 - 1.2e-28 99.7 0.0 4e-28 98.1 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RLN90402.1 - 1.3e-12 47.8 0.0 5e-05 23.3 0.0 3.6 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) DUF853 PF05872.12 RLN90402.1 - 0.00094 17.9 1.3 0.15 10.6 0.1 2.2 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF853) AAA_22 PF13401.6 RLN90402.1 - 0.0022 18.2 1.1 2.1 8.6 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 RLN90402.1 - 0.0057 17.1 0.9 2.2 8.6 0.0 3.9 3 0 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.22 RLN90402.1 - 0.0059 17.0 0.0 2.1 8.8 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 RLN90402.1 - 0.006 17.1 0.0 0.24 11.9 0.0 3.5 3 0 0 3 3 2 1 AAA domain AAA_7 PF12775.7 RLN90402.1 - 0.015 14.8 0.9 6.1 6.3 0.0 3.2 3 0 0 3 3 3 0 P-loop containing dynein motor region NFRKB_winged PF14465.6 RLN90402.1 - 0.06 13.5 6.0 0.11 12.7 0.2 3.7 3 0 0 3 3 2 0 NFRKB Winged Helix-like AAA_30 PF13604.6 RLN90402.1 - 0.07 12.9 0.8 3.2 7.4 0.3 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RLN90402.1 - 0.12 12.7 0.0 32 4.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain SIKE PF05769.11 RLN90402.1 - 0.15 12.0 6.9 0.18 11.7 1.0 3.0 1 1 1 2 2 2 0 SIKE family AAA PF00004.29 RLN90402.1 - 0.26 11.7 2.7 0.48 10.8 0.1 2.9 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) Vps54_N PF10475.9 RLN90402.1 - 0.34 10.1 6.8 0.12 11.7 2.5 2.4 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex DUF87 PF01935.17 RLN90402.1 - 6.7 6.7 11.1 0.74 9.9 0.1 3.4 4 0 0 4 4 4 0 Helicase HerA, central domain polyprenyl_synt PF00348.17 RLN90403.1 - 2.6e-70 236.4 0.2 4e-66 222.7 0.3 2.5 1 1 1 2 2 2 2 Polyprenyl synthetase PIG-P PF08510.12 RLN90404.1 - 0.16 11.9 5.4 0.55 10.2 5.4 1.9 1 0 0 1 1 1 0 PIG-P Pkinase PF00069.25 RLN90405.1 - 2e-10 40.5 0.0 2.3e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 RLN90406.1 - 5.2e-40 137.5 0.1 6.7e-40 137.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90406.1 - 1.8e-19 70.0 0.1 2.5e-19 69.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN90406.1 - 1.8e-06 27.4 0.1 2.6e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN90406.1 - 6.2e-05 23.0 0.0 0.0027 17.7 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RLN90406.1 - 0.00076 18.9 0.1 0.0014 18.0 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 RLN90406.1 - 0.053 13.1 0.2 0.082 12.5 0.2 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase TPR_12 PF13424.6 RLN90407.1 - 1e-12 48.2 14.0 0.00065 19.9 0.5 4.9 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 RLN90407.1 - 7.1e-09 35.2 11.3 0.57 10.5 0.4 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN90407.1 - 5.4e-06 26.1 12.8 0.065 13.3 0.1 5.6 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN90407.1 - 0.00076 19.4 16.6 0.74 10.1 0.2 5.6 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN90407.1 - 0.002 17.9 13.5 0.27 11.1 0.1 6.3 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN90407.1 - 0.0028 18.3 13.7 0.38 11.7 0.9 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 RLN90407.1 - 0.013 16.1 5.6 2.3 9.0 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN90407.1 - 0.42 10.5 12.3 0.94 9.4 0.9 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat RRM_1 PF00076.22 RLN90408.1 - 7.4e-09 35.3 0.0 9.7e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CASP_C PF08172.12 RLN90409.1 - 9e-62 208.7 0.0 9e-62 208.7 0.0 4.3 3 1 1 5 5 5 1 CASP C terminal DUF4677 PF15726.5 RLN90409.1 - 0.0039 17.4 0.3 0.011 15.9 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4677) VGPC1_C PF16799.5 RLN90409.1 - 0.16 11.9 3.2 13 5.8 0.7 3.3 3 0 0 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 DUF2721 PF11026.8 RLN90409.1 - 0.39 10.6 0.0 0.39 10.6 0.0 4.6 5 1 0 5 5 5 0 Protein of unknown function (DUF2721) DUF1664 PF07889.12 RLN90409.1 - 8.8 6.4 26.7 0.22 11.6 2.7 5.4 2 1 4 6 6 6 0 Protein of unknown function (DUF1664) Peptidase_S24 PF00717.23 RLN90410.1 - 1.4e-09 37.8 0.0 4.7e-09 36.1 0.0 1.8 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 RLN90410.1 - 0.0046 16.7 0.0 4.3 7.1 0.0 2.9 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_U32_C PF16325.5 RLN90410.1 - 0.14 12.4 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family U32 C-terminal domain FYVE PF01363.21 RLN90411.1 - 4.6e-17 61.9 10.0 4.6e-17 61.9 10.0 2.6 2 1 0 2 2 2 1 FYVE zinc finger DEP PF00610.21 RLN90411.1 - 0.003 17.6 0.0 0.0059 16.6 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FYVE_2 PF02318.16 RLN90411.1 - 0.0067 16.6 5.6 0.0067 16.6 5.6 2.5 2 0 0 2 2 2 1 FYVE-type zinc finger PLATZ PF04640.14 RLN90411.1 - 0.041 14.5 2.1 0.041 14.5 2.1 2.6 3 1 0 3 3 3 0 PLATZ transcription factor EF-hand_1 PF00036.32 RLN90412.1 - 8.4e-16 56.3 12.0 0.00045 19.6 0.5 4.7 3 1 1 4 4 4 4 EF hand EF-hand_7 PF13499.6 RLN90412.1 - 2.8e-15 56.5 3.3 3.7e-07 30.5 1.1 2.9 1 1 1 2 2 2 2 EF-hand domain pair LRR_6 PF13516.6 RLN90412.1 - 3e-15 54.9 18.3 0.0028 17.6 0.6 8.2 8 0 0 8 8 8 4 Leucine Rich repeat EF-hand_6 PF13405.6 RLN90412.1 - 7.6e-14 50.4 6.6 0.00013 21.6 0.2 4.9 2 1 2 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 RLN90412.1 - 6.8e-09 34.8 7.5 0.00083 18.8 0.3 4.2 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 RLN90412.1 - 6.8e-06 25.8 6.6 0.12 12.2 0.0 4.0 3 0 0 3 3 3 2 EF-hand domain pair DUF4476 PF14771.6 RLN90412.1 - 4.3e-05 23.7 0.3 0.0025 18.1 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4476) LRR_1 PF00560.33 RLN90412.1 - 0.086 13.4 7.6 1.3e+02 3.8 0.1 5.6 5 0 0 5 5 4 0 Leucine Rich Repeat EF-hand_10 PF14788.6 RLN90412.1 - 0.28 11.1 2.9 80 3.2 0.0 4.3 3 1 1 4 4 4 0 EF hand LRR_8 PF13855.6 RLN90412.1 - 0.4 10.5 13.0 1.1 9.1 1.9 4.3 4 1 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 RLN90412.1 - 1.5 9.3 10.4 29 5.3 1.3 4.5 2 2 4 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN90413.1 - 2.2e-08 33.7 0.9 3e-08 33.3 0.9 1.2 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 RLN90413.1 - 1.3e-06 28.7 8.0 0.00076 19.8 0.9 1.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN90413.1 - 0.039 14.5 1.7 3.2 8.7 1.4 2.5 2 1 0 2 2 2 0 Leucine Rich Repeat LRR_9 PF14580.6 RLN90413.1 - 0.088 12.3 0.0 0.098 12.1 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeat MAD PF05557.13 RLN90414.1 - 0.0032 15.9 1.7 0.0046 15.4 1.7 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein LRR_9 PF14580.6 RLN90414.1 - 0.0046 16.5 0.9 0.65 9.5 0.0 2.9 2 1 1 3 3 3 2 Leucine-rich repeat LRR_4 PF12799.7 RLN90414.1 - 0.031 14.7 10.3 0.73 10.3 0.4 4.3 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) DUF465 PF04325.13 RLN90414.1 - 0.087 12.9 0.8 0.35 10.9 0.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF465) FerA PF08165.11 RLN90414.1 - 1 9.3 3.7 1.8 8.6 0.1 2.9 3 0 0 3 3 3 0 FerA (NUC095) domain Glyco_hydro81C PF17652.1 RLN90415.1 - 1.6e-118 396.0 1.9 2.3e-118 395.4 1.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 RLN90415.1 - 2.5e-46 158.3 1.5 3.7e-46 157.8 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Zw10 PF06248.13 RLN90417.1 - 3.5e-47 161.2 0.9 9.1e-47 159.8 0.9 1.7 1 1 0 1 1 1 1 Centromere/kinetochore Zw10 Exo84_C PF16528.5 RLN90417.1 - 0.025 14.4 2.0 0.037 13.8 0.2 2.2 2 1 0 2 2 2 0 Exocyst component 84 C-terminal CorA PF01544.18 RLN90418.1 - 7.2e-56 189.6 1.1 1.8e-45 155.5 0.8 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Myb_DNA-binding PF00249.31 RLN90419.1 - 9.7e-11 41.7 0.0 9.7e-11 41.7 0.0 2.0 3 0 0 3 3 3 1 Myb-like DNA-binding domain DUF4200 PF13863.6 RLN90419.1 - 0.011 16.2 0.6 0.028 14.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Herpes_capsid PF06112.11 RLN90419.1 - 9.6 6.2 15.1 13 5.8 0.3 2.2 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein EB PF01683.18 RLN90420.1 - 8.2 6.8 6.7 1.8 8.9 1.3 2.4 2 0 0 2 2 2 0 EB module Pkinase PF00069.25 RLN90422.1 - 2.4e-45 155.0 0.0 3.4e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90422.1 - 6.2e-40 137.1 0.0 8.7e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN90422.1 - 0.037 14.0 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Scramblase PF03803.15 RLN90422.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Scramblase SWI-SNF_Ssr4 PF08549.10 RLN90422.1 - 0.81 8.2 13.0 1.1 7.8 13.0 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Pkinase_fungal PF17667.1 RLN90422.1 - 1.6 7.4 3.5 0.56 8.9 0.1 1.7 2 0 0 2 2 2 0 Fungal protein kinase ATP_bind_1 PF03029.17 RLN90423.1 - 5.5e-71 239.1 1.3 7.5e-71 238.7 0.3 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 RLN90423.1 - 1.2e-08 34.7 0.0 9.2e-08 31.8 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 RLN90423.1 - 2.6e-06 27.0 0.0 3.9e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 RLN90423.1 - 0.0012 18.9 0.0 0.0094 16.0 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 RLN90423.1 - 0.0028 17.3 0.1 1.7 8.2 0.1 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 RLN90423.1 - 0.0039 16.4 0.1 2 7.5 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_16 PF13191.6 RLN90423.1 - 0.011 16.1 0.5 0.03 14.7 0.1 2.1 1 1 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 RLN90423.1 - 0.012 14.8 0.1 0.034 13.3 0.1 1.7 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 RLN90423.1 - 0.013 15.4 0.1 2.7 7.9 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase PduV-EutP PF10662.9 RLN90423.1 - 0.02 14.6 0.4 0.57 9.9 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 RLN90423.1 - 0.024 14.1 0.0 3.8 6.9 0.0 2.5 2 1 0 2 2 2 0 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RLN90423.1 - 0.04 13.3 0.2 0.78 9.0 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region NACHT PF05729.12 RLN90423.1 - 0.049 13.6 0.4 0.11 12.4 0.4 1.6 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 RLN90423.1 - 0.052 13.3 0.3 0.1 12.3 0.3 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RLN90423.1 - 0.1 12.9 0.7 1.2 9.4 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_29 PF13555.6 RLN90423.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 RLN90423.1 - 0.11 12.2 0.2 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 RLN90423.1 - 0.12 12.5 0.3 0.42 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain PP2C_C PF07830.13 RLN90423.1 - 0.14 12.6 0.2 0.28 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain AAA_18 PF13238.6 RLN90423.1 - 0.19 12.3 0.3 1.6 9.3 0.0 2.4 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.25 RLN90424.1 - 1.9e-47 161.8 0.0 2.5e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90424.1 - 1.4e-44 152.3 0.0 1.8e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase SKG6 PF08693.10 RLN90424.1 - 0.0077 15.6 2.1 0.017 14.5 2.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Pkinase_fungal PF17667.1 RLN90424.1 - 0.016 14.0 0.1 0.025 13.4 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 RLN90424.1 - 0.021 14.7 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family CcmD PF04995.14 RLN90424.1 - 0.027 14.5 3.5 0.067 13.3 3.5 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) PepSY_TM PF03929.16 RLN90424.1 - 0.043 13.5 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 PepSY-associated TM region DUF4381 PF14316.6 RLN90424.1 - 0.047 13.9 0.2 0.084 13.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4448 PF14610.6 RLN90424.1 - 0.098 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TAS2R PF05296.13 RLN90424.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) Haspin_kinase PF12330.8 RLN90424.1 - 0.11 11.4 0.0 0.78 8.6 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain VSP PF03302.13 RLN90424.1 - 0.69 8.7 1.1 1 8.2 1.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Pkinase PF00069.25 RLN90425.1 - 4.4e-32 111.5 0.0 5.3e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90425.1 - 4.6e-25 88.4 0.0 5.4e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN90425.1 - 0.021 14.8 0.1 0.04 13.8 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN90425.1 - 0.11 11.3 0.1 0.15 10.9 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase Scramblase PF03803.15 RLN90425.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Scramblase Pkinase_Tyr PF07714.17 RLN90426.1 - 1.5e-35 122.7 0.0 2.3e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN90426.1 - 3.3e-29 102.1 0.0 5.2e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain stn_TNFRSF12A PF12191.8 RLN90426.1 - 0.017 15.3 0.0 0.051 13.8 0.0 1.8 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Herpes_gE PF02480.16 RLN90426.1 - 0.018 13.8 0.0 0.032 13.0 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.6 RLN90426.1 - 0.056 13.4 0.0 0.31 10.9 0.0 2.0 1 1 1 2 2 2 0 TMEM154 protein family CEND1 PF15677.5 RLN90426.1 - 0.075 13.6 0.2 0.18 12.3 0.2 1.6 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 FixS PF03597.15 RLN90426.1 - 0.098 12.4 0.2 7.7 6.3 0.1 2.3 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Rax2 PF12768.7 RLN90426.1 - 0.14 11.6 0.1 0.5 9.8 0.0 1.9 1 1 1 2 2 2 0 Cortical protein marker for cell polarity P53_TAD PF08563.11 RLN90426.1 - 0.69 9.5 4.2 0.3 10.6 0.6 2.2 2 0 0 2 2 2 0 P53 transactivation motif Pkinase_Tyr PF07714.17 RLN90427.1 - 1.1e-50 172.3 0.0 1.5e-50 171.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN90427.1 - 1.7e-48 165.3 0.0 2.4e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 RLN90427.1 - 0.0036 17.3 0.0 0.024 14.5 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN90427.1 - 0.049 12.4 0.0 0.074 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FXMRP1_C_core PF12235.8 RLN90427.1 - 0.51 11.0 1.3 1.1 9.9 1.3 1.5 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Pkinase_Tyr PF07714.17 RLN90429.1 - 1e-37 129.9 0.0 1.3e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN90429.1 - 1.2e-34 119.9 0.0 1.8e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 RLN90429.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN90429.1 - 0.21 10.9 0.0 0.48 9.7 0.0 1.5 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 RLN90430.1 - 4.2e-50 170.5 0.0 5.7e-50 170.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN90430.1 - 8.6e-48 163.0 0.0 1.2e-47 162.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 RLN90430.1 - 0.0067 15.4 0.0 0.04 12.9 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 RLN90430.1 - 0.041 12.7 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Orthoreo_P10 PF07204.11 RLN90430.1 - 0.042 13.8 0.0 0.097 12.6 0.0 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 APH PF01636.23 RLN90430.1 - 0.09 12.7 0.1 0.81 9.6 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 RLN90431.1 - 1e-49 169.3 0.0 1.4e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90431.1 - 8.7e-49 166.1 0.0 1.1e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CD34_antigen PF06365.12 RLN90431.1 - 0.00011 21.9 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family APH PF01636.23 RLN90431.1 - 0.0025 17.8 0.0 0.058 13.3 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN90431.1 - 0.0056 15.7 0.0 0.015 14.2 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain EphA2_TM PF14575.6 RLN90431.1 - 0.012 16.5 0.1 0.086 13.7 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 RLN90431.1 - 0.013 15.4 0.0 0.037 13.9 0.0 1.7 2 0 0 2 2 2 0 TMEM154 protein family Pkinase_fungal PF17667.1 RLN90431.1 - 0.015 14.1 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase G6B PF15096.6 RLN90431.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 G6B family LSR PF05624.14 RLN90431.1 - 1.1 9.3 3.7 2.9 8.0 3.7 1.7 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) DDE_Tnp_1_7 PF13843.6 RLN90432.1 - 0.00014 21.3 0.1 0.00018 21.0 0.1 1.1 1 0 0 1 1 1 1 Transposase IS4 Glyco_hydro_85 PF03644.13 RLN90434.1 - 5e-49 167.4 0.0 2.1e-48 165.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 85 ABC_cobalt PF09819.9 RLN90434.1 - 0.15 12.2 0.1 0.32 11.2 0.1 1.5 1 0 0 1 1 1 0 ABC-type cobalt transport system, permease component ABC2_membrane PF01061.24 RLN90435.1 - 4.8e-38 130.7 30.2 4.8e-38 130.7 30.2 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RLN90435.1 - 3.7e-28 98.7 0.9 5.5e-18 65.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 RLN90435.1 - 1.8e-06 28.0 2.6 0.013 15.4 0.3 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 RLN90435.1 - 3.2e-06 26.8 6.9 0.0074 16.0 0.9 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN90435.1 - 3.5e-05 24.3 0.9 0.041 14.2 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain AAA_25 PF13481.6 RLN90435.1 - 5.6e-05 22.8 1.1 0.072 12.7 0.1 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN90435.1 - 8.6e-05 21.9 1.3 0.013 14.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin ABC2_membrane_3 PF12698.7 RLN90435.1 - 0.00014 21.1 12.7 0.00014 21.1 12.7 2.5 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_22 PF13401.6 RLN90435.1 - 0.00028 21.2 2.0 0.37 11.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 RLN90435.1 - 0.0016 18.5 1.1 0.6 10.2 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 RLN90435.1 - 0.0017 18.2 0.3 1.9 8.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RLN90435.1 - 0.0021 18.6 2.7 0.34 11.4 0.4 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RLN90435.1 - 0.0026 18.3 0.3 0.98 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 RLN90435.1 - 0.0037 17.3 0.5 0.2 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 RLN90435.1 - 0.0066 16.2 3.5 2.4 7.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 RLN90435.1 - 0.012 15.8 0.8 4.9 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain PDR_assoc PF08370.11 RLN90435.1 - 0.013 15.3 0.2 0.013 15.3 0.2 2.9 3 0 0 3 3 2 0 Plant PDR ABC transporter associated AAA PF00004.29 RLN90435.1 - 0.013 15.9 0.5 2.8 8.4 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 RLN90435.1 - 0.014 15.0 1.5 0.84 9.2 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 RLN90435.1 - 0.014 15.6 0.7 2.2 8.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ploopntkinase3 PF18751.1 RLN90435.1 - 0.017 15.1 1.3 0.25 11.3 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 RLN90435.1 - 0.019 15.3 0.7 3.8 8.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 RLN90435.1 - 0.028 14.2 0.9 5.2 6.7 0.3 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 RLN90435.1 - 0.028 13.6 0.9 0.063 12.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.12 RLN90435.1 - 0.033 14.1 3.9 4.2 7.3 0.6 2.7 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 RLN90435.1 - 0.04 13.6 1.5 3 7.6 0.3 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 RLN90435.1 - 0.042 13.0 0.3 0.15 11.2 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit ATP-synt_ab PF00006.25 RLN90435.1 - 0.054 13.1 0.9 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 RLN90435.1 - 0.065 13.2 0.8 3.3 7.7 0.2 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 RLN90435.1 - 0.071 12.9 0.3 9.3 6.0 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain VirE PF05272.11 RLN90435.1 - 0.1 12.3 0.3 0.75 9.5 0.0 2.1 2 0 0 2 2 2 0 Virulence-associated protein E Gtr1_RagA PF04670.12 RLN90435.1 - 0.13 11.6 1.6 7.5 5.8 0.1 2.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DUF87 PF01935.17 RLN90435.1 - 0.13 12.3 4.5 2.8 8.0 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain DUF1563 PF07599.11 RLN90435.1 - 0.13 12.3 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) SMC_N PF02463.19 RLN90435.1 - 0.16 11.4 4.9 6.6 6.1 0.1 3.3 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain FeoB_N PF02421.18 RLN90435.1 - 0.2 11.1 0.4 13 5.2 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 RLN90435.1 - 0.25 10.9 1.6 3.8 7.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 RLN90435.1 - 0.33 11.2 1.6 14 5.9 0.6 2.5 2 0 0 2 2 2 0 AAA domain DUF4227 PF14004.6 RLN90435.1 - 1.6 8.8 4.0 0.84 9.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) AAA_13 PF13166.6 RLN90437.1 - 0.23 10.1 14.0 0.34 9.5 14.0 1.2 1 0 0 1 1 1 0 AAA domain Borrelia_P83 PF05262.11 RLN90437.1 - 2.5 6.5 14.8 4 5.8 14.8 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein zf_UBZ PF18439.1 RLN90437.1 - 6.5 6.5 17.3 44 3.8 0.1 6.1 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger Ribosomal_S8e PF01201.22 RLN90438.1 - 4.4e-52 175.9 1.9 4.4e-52 175.9 1.9 2.0 2 0 0 2 2 2 1 Ribosomal protein S8e DNA_primase_S PF01896.19 RLN90439.1 - 1.5e-51 174.9 0.0 2.1e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 DNA primase small subunit DUF3398 PF11878.8 RLN90439.1 - 0.17 12.3 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) POPLD PF08170.12 RLN90440.1 - 1.6e-21 76.5 1.5 4e-21 75.2 0.0 2.3 2 1 0 2 2 2 1 POPLD (NUC188) domain POP1 PF06978.11 RLN90440.1 - 8.6e-13 48.7 19.0 1.8e-12 47.7 0.1 2.6 2 1 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 IFT57 PF10498.9 RLN90441.1 - 2.1 7.2 14.6 7.2 5.5 14.6 1.9 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 TSC22 PF01166.18 RLN90442.1 - 0.0014 18.9 9.8 0.37 11.1 3.2 3.5 3 0 0 3 3 3 2 TSC-22/dip/bun family LPP PF04728.13 RLN90442.1 - 0.061 13.7 1.0 1.5 9.2 0.3 3.1 2 0 0 2 2 2 0 Lipoprotein leucine-zipper ZapB PF06005.12 RLN90442.1 - 0.087 13.3 23.1 0.22 12.0 4.5 5.1 4 2 0 4 4 4 0 Cell division protein ZapB NPV_P10 PF05531.12 RLN90442.1 - 0.27 11.7 7.4 0.68 10.4 0.8 4.2 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 RLN90442.1 - 0.4 11.3 0.0 0.4 11.3 0.0 5.0 3 1 0 4 4 4 0 SlyX DUF5595 PF18077.1 RLN90442.1 - 0.41 10.8 0.1 0.41 10.8 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) DivIC PF04977.15 RLN90442.1 - 0.83 9.5 16.5 5.2 6.9 0.1 4.9 3 1 2 5 5 5 0 Septum formation initiator DASH_Dad4 PF08650.10 RLN90442.1 - 1.8 8.6 9.4 0.34 10.9 0.1 3.8 3 2 2 5 5 5 0 DASH complex subunit Dad4 DUF4140 PF13600.6 RLN90442.1 - 3.4 8.1 12.5 41 4.7 6.6 3.8 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF745 PF05335.13 RLN90442.1 - 3.7 7.2 8.5 0.89 9.2 2.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF745) FlaC_arch PF05377.11 RLN90442.1 - 6.8 7.2 16.1 9.5 6.7 2.7 4.7 4 1 1 5 5 4 0 Flagella accessory protein C (FlaC) Pox_A_type_inc PF04508.12 RLN90442.1 - 7.9 6.5 7.4 3.3 7.7 2.1 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Hemagglutinin PF00509.18 RLN90442.1 - 8.7 4.6 9.5 0.59 8.5 3.3 2.0 2 1 1 3 3 3 0 Haemagglutinin SIR2 PF02146.17 RLN90443.1 - 7.3e-51 172.6 0.0 9.4e-51 172.2 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 RLN90443.1 - 0.0064 16.2 0.0 0.45 10.2 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 RLN90443.1 - 0.068 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF592) UvrC_HhH_N PF08459.11 RLN90443.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal MA3 PF02847.17 RLN90444.1 - 1e-32 112.4 1.0 2.3e-15 56.5 0.0 3.1 3 0 0 3 3 3 2 MA3 domain MIF4G PF02854.19 RLN90444.1 - 3.9e-12 46.3 1.7 6.4e-11 42.3 1.7 2.7 1 1 0 1 1 1 1 MIF4G domain DUF1707 PF08044.11 RLN90444.1 - 1.4 9.0 4.5 7.3 6.7 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) DUF4148 PF13663.6 RLN90444.1 - 1.6 9.0 3.6 1 9.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) TRM PF02005.16 RLN90445.1 - 1.9e-124 415.7 0.0 2.2e-124 415.4 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 RLN90445.1 - 0.0088 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 RLN90445.1 - 0.038 13.6 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TPR_1 PF00515.28 RLN90446.1 - 3.6e-16 58.2 10.5 6.5e-06 25.7 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat Prefoldin PF02996.17 RLN90446.1 - 4.6e-15 55.6 3.7 7.8e-15 54.8 0.0 2.8 3 0 0 3 3 3 1 Prefoldin subunit TPR_2 PF07719.17 RLN90446.1 - 6.9e-14 50.8 13.7 1.2e-06 28.2 0.3 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 RLN90446.1 - 3.6e-06 27.0 8.7 0.00076 19.6 3.5 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN90446.1 - 1.2e-05 25.2 4.8 0.25 11.6 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN90446.1 - 1.4e-05 24.6 0.7 0.0026 17.4 0.2 2.8 2 1 1 3 3 3 1 TPR repeat TPR_17 PF13431.6 RLN90446.1 - 0.00025 21.2 2.8 0.0078 16.5 0.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN90446.1 - 0.00096 19.4 14.1 0.01 16.1 7.0 3.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN90446.1 - 0.003 18.1 15.0 0.18 12.5 8.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat NYD-SP12_N PF15015.6 RLN90446.1 - 0.0058 15.1 0.2 0.0097 14.3 0.2 1.3 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal TPR_14 PF13428.6 RLN90446.1 - 0.37 11.7 19.1 0.44 11.5 0.6 4.6 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN90446.1 - 1 9.3 15.7 0.78 9.7 2.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN90446.1 - 8.1 7.0 15.3 1.2 9.7 3.6 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat fn3 PF00041.21 RLN90447.1 - 2.2e-08 34.3 0.0 2.9e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Fibronectin type III domain Kinesin PF00225.23 RLN90448.1 - 5.3e-13 48.6 3.6 6.4e-13 48.3 0.0 2.9 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 RLN90448.1 - 8.8e-08 32.2 0.0 4e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding zf-MYND PF01753.18 RLN90449.1 - 1.3e-10 41.1 13.0 2.9e-10 40.1 13.0 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 RLN90449.1 - 0.024 14.9 9.4 0.07 13.5 9.4 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Rhodanese_C PF12368.8 RLN90449.1 - 0.068 13.6 4.9 0.19 12.1 4.9 1.7 1 0 0 1 1 1 0 Rhodanase C-terminal DUF1247 PF06851.11 RLN90449.1 - 0.19 11.6 2.4 11 5.9 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1247) zf-HIT PF04438.16 RLN90449.1 - 2.6 8.0 8.4 6.5 6.7 8.4 1.7 1 0 0 1 1 1 0 HIT zinc finger EF-hand_1 PF00036.32 RLN90451.1 - 3.2e-11 41.9 5.0 5.2e-06 25.6 0.2 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 RLN90451.1 - 8.2e-11 42.2 1.8 0.0012 19.2 0.1 3.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN90451.1 - 2.1e-10 39.6 1.9 8e-05 22.0 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN90451.1 - 1.7e-09 36.8 3.8 8.7e-06 25.3 0.4 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 RLN90451.1 - 1e-07 31.7 0.6 0.0033 17.2 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 RLN90451.1 - 0.14 12.1 0.2 3.5 7.6 0.1 2.3 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RLN90451.1 - 0.16 12.3 0.0 18 5.7 0.0 2.4 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Apt1 PF10351.9 RLN90452.1 - 0.00067 18.6 2.1 0.002 17.1 0.0 2.6 3 0 0 3 3 3 1 Golgi-body localisation protein domain Glyco_hydro_47 PF01532.20 RLN90453.1 - 5.2e-76 256.4 2.8 3.2e-41 141.7 0.0 3.0 1 1 2 3 3 3 3 Glycosyl hydrolase family 47 Peptidase_M41 PF01434.18 RLN90455.1 - 1.7e-63 213.9 0.1 2.4e-63 213.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 RLN90455.1 - 2.2e-13 49.8 0.2 4.9e-13 48.6 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 RLN90455.1 - 8.7e-10 39.1 0.0 1.8e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MOR2-PAG1_C PF14225.6 RLN90456.1 - 4.8e-05 23.3 0.4 4.8e-05 23.3 0.4 3.9 4 1 1 5 5 5 2 Cell morphogenesis C-terminal FAD_binding_1 PF00667.20 RLN90457.1 - 1.4e-60 204.7 0.0 2.1e-60 204.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 RLN90457.1 - 2.2e-33 115.5 0.4 4.9e-33 114.3 0.4 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 RLN90457.1 - 6.1e-20 71.9 0.1 1.9e-19 70.3 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 RLN90457.1 - 0.04 14.0 0.0 0.22 11.6 0.0 1.9 1 1 1 2 2 2 0 Ferric reductase NAD binding domain Lipocalin_5 PF13924.6 RLN90458.1 - 0.0071 16.1 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Lipocalin-like domain DUF5004 PF16395.5 RLN90458.1 - 0.059 13.4 0.0 0.069 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5004) Chitin_synth_1 PF01644.17 RLN90459.1 - 2.5e-50 170.6 0.1 4.1e-50 169.9 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 RLN90459.1 - 6.2e-24 84.5 0.2 2.6e-20 72.6 0.0 3.1 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 RLN90459.1 - 5.1e-09 36.3 3.1 5.1e-09 36.3 3.1 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Chitin_synth_1N PF08407.11 RLN90459.1 - 1e-05 25.3 0.0 4.4e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_tranf_2_3 PF13641.6 RLN90459.1 - 1.5e-05 25.0 0.0 3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 PRP38_assoc PF12871.7 RLN90460.1 - 0.056 14.0 46.9 0.093 13.3 46.9 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term CDC45 PF02724.14 RLN90460.1 - 1.5 7.0 16.1 1.5 7.0 16.1 1.1 1 0 0 1 1 1 0 CDC45-like protein VPS9 PF02204.18 RLN90462.1 - 8.1e-11 42.1 0.0 8.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF2529 PF10740.9 RLN90462.1 - 0.06 13.0 0.0 0.066 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) ZZ PF00569.17 RLN90463.1 - 6.1e-14 51.6 12.9 1.3e-06 28.1 4.7 2.8 2 0 0 2 2 2 2 Zinc finger, ZZ type Ank_5 PF13857.6 RLN90463.1 - 1.5e-09 37.9 0.1 0.0052 17.1 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Tektin PF03148.14 RLN90463.1 - 0.011 14.5 2.9 0.03 13.1 2.9 1.6 1 0 0 1 1 1 0 Tektin family Ank_3 PF13606.6 RLN90463.1 - 0.029 14.9 0.0 26 5.8 0.0 3.1 2 0 0 2 2 2 0 Ankyrin repeat DUF1664 PF07889.12 RLN90463.1 - 0.072 13.1 1.0 1.2 9.2 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 RLN90463.1 - 0.082 13.4 4.0 0.11 13.0 0.8 2.8 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein Nsp1_C PF05064.13 RLN90463.1 - 0.085 12.7 7.6 0.12 12.2 2.1 3.5 3 0 0 3 3 3 0 Nsp1-like C-terminal region DUF4428 PF14471.6 RLN90463.1 - 0.1 12.5 2.2 5.2 7.1 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) DUF2451 PF10474.9 RLN90463.1 - 0.11 12.2 0.2 0.87 9.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) MapZ_EC1 PF18041.1 RLN90463.1 - 0.19 12.0 1.3 0.92 9.8 0.1 2.5 2 0 0 2 2 2 0 MapZ extracellular domain 1 Seryl_tRNA_N PF02403.22 RLN90463.1 - 0.21 11.8 2.2 0.66 10.2 0.5 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Sec2p PF06428.11 RLN90463.1 - 0.36 10.8 10.0 2.9 7.9 0.1 3.0 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p LPP PF04728.13 RLN90463.1 - 0.52 10.7 4.9 0.25 11.8 2.0 2.0 2 0 0 2 2 2 0 Lipoprotein leucine-zipper BLOC1_2 PF10046.9 RLN90463.1 - 0.89 9.9 4.5 1.4 9.3 0.6 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 RLN90463.1 - 5 7.8 7.5 1.8 9.2 2.3 3.0 3 0 0 3 3 2 0 SlyX RVT_1 PF00078.27 RLN90464.1 - 1.5e-13 50.8 0.0 3.8e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFIIS_M PF07500.14 RLN90464.1 - 0.096 13.2 1.2 0.43 11.1 0.4 2.2 1 1 2 3 3 3 0 Transcription factor S-II (TFIIS), central domain DUF2959 PF11172.8 RLN90464.1 - 0.14 12.3 3.5 0.21 11.7 2.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) TetR_C_6 PF13977.6 RLN90464.1 - 5.4 7.3 9.9 0.51 10.6 4.0 2.4 2 1 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal FYVE PF01363.21 RLN90465.1 - 1.8e-12 47.2 5.5 1.8e-12 47.2 5.5 1.7 2 0 0 2 2 2 1 FYVE zinc finger START PF01852.19 RLN90465.1 - 5e-06 26.1 0.1 8.1e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 START domain FYVE_2 PF02318.16 RLN90465.1 - 2.2e-05 24.6 1.6 4.9e-05 23.5 1.6 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger HypA PF01155.19 RLN90465.1 - 0.28 11.2 4.6 0.21 11.6 1.4 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-piccolo PF05715.13 RLN90465.1 - 1.1 9.4 7.7 6.3 7.0 7.8 2.2 1 1 0 1 1 1 0 Piccolo Zn-finger Ribosomal_S27e PF01667.17 RLN90465.1 - 1.8 8.3 7.7 0.84 9.4 4.3 2.1 2 0 0 2 2 2 0 Ribosomal protein S27 DZR PF12773.7 RLN90465.1 - 6.3 6.9 8.8 11 6.2 2.8 2.6 2 1 1 3 3 3 0 Double zinc ribbon Dicty_REP PF05086.12 RLN90466.1 - 0.11 10.5 1.5 0.13 10.2 1.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3332 PF11810.8 RLN90466.1 - 0.23 11.1 1.1 0.34 10.5 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) Macoilin PF09726.9 RLN90466.1 - 0.35 9.4 7.2 0.46 9.0 7.2 1.1 1 0 0 1 1 1 0 Macoilin family VIR_N PF15912.5 RLN90467.1 - 2.4 7.7 8.9 2.8 7.5 8.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal SWIRM-assoc_2 PF16496.5 RLN90467.1 - 4.3 6.1 15.6 4.7 6.0 15.6 1.0 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Pkinase PF00069.25 RLN90468.1 - 8.1e-42 143.4 0.0 1e-41 143.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90468.1 - 1.8e-28 99.5 0.0 2.4e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN90468.1 - 1.2e-05 24.8 0.0 1.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RLN90468.1 - 8.4e-05 21.5 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase AID PF18767.1 RLN90468.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Activation induced deaminase RIO1 PF01163.22 RLN90468.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family tRNA_U5-meth_tr PF05958.11 RLN90469.1 - 1.2e-12 47.5 0.0 2.5e-12 46.5 0.0 1.5 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase MTS PF05175.14 RLN90469.1 - 0.00059 19.4 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 RLN90469.1 - 0.0016 18.3 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltrans_SAM PF10672.9 RLN90469.1 - 0.0022 17.2 0.6 0.014 14.6 0.3 2.4 2 1 0 2 2 2 1 S-adenosylmethionine-dependent methyltransferase Methyltransf_31 PF13847.6 RLN90469.1 - 0.0054 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN90469.1 - 0.067 13.9 0.0 0.2 12.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 RLN90469.1 - 0.14 11.9 0.0 0.4 10.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_15 PF09445.10 RLN90469.1 - 0.15 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 RLN90469.1 - 0.19 11.1 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PIH1 PF08190.12 RLN90470.1 - 3.1e-23 82.1 0.0 5.5e-22 78.0 0.0 2.5 3 0 0 3 3 3 1 PIH1 N-terminal domain RsgI_N PF12791.7 RLN90470.1 - 0.031 14.2 0.1 0.077 12.9 0.1 1.6 1 0 0 1 1 1 0 Anti-sigma factor N-terminus IQ PF00612.27 RLN90471.1 - 0.0002 20.9 4.6 0.027 14.2 0.2 3.4 2 0 0 2 2 2 2 IQ calmodulin-binding motif CNOT11 PF10155.9 RLN90472.1 - 0.095 12.9 0.1 1.9 8.6 0.0 2.8 3 0 0 3 3 3 0 CCR4-NOT transcription complex subunit 11 SNAD2 PF18745.1 RLN90472.1 - 0.15 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 2 HAUS5 PF14817.6 RLN90474.1 - 0.036 12.8 0.8 0.043 12.6 0.8 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Ead_Ea22 PF13935.6 RLN90474.1 - 0.038 14.7 0.1 0.046 14.4 0.1 1.1 1 0 0 1 1 1 0 Ead/Ea22-like protein Flg_hook PF02120.16 RLN90474.1 - 0.11 12.4 0.3 0.11 12.4 0.3 1.6 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK DUF4988 PF16378.5 RLN90475.1 - 0.034 13.8 0.1 0.049 13.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function p450 PF00067.22 RLN90476.1 - 6.6e-31 107.6 0.0 7.6e-31 107.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NPC1_N PF16414.5 RLN90478.1 - 1.1e-16 61.1 12.2 2.4e-16 60.1 12.2 1.5 1 1 0 1 1 1 1 Niemann-Pick C1 N terminus Folate_rec PF03024.14 RLN90478.1 - 9.6e-06 25.6 5.6 9.6e-06 25.6 5.6 1.6 2 0 0 2 2 2 1 Folate receptor family Uso1_p115_head PF04869.14 RLN90479.1 - 5.4e-21 75.0 0.1 2.6e-18 66.2 0.1 2.5 1 1 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region HEAT PF02985.22 RLN90479.1 - 0.52 10.7 6.0 3.1 8.3 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat DUF4988 PF16378.5 RLN90480.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function EF-hand_6 PF13405.6 RLN90481.1 - 6.1e-06 25.8 0.1 0.0099 15.7 0.0 3.7 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 RLN90481.1 - 1.8e-05 25.1 0.0 0.00043 20.7 0.0 2.8 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN90481.1 - 3.2e-05 23.2 0.0 0.0087 15.5 0.0 3.3 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 RLN90481.1 - 0.00031 20.1 0.1 0.025 14.1 0.1 2.4 2 0 0 2 2 2 1 EF hand ZZ PF00569.17 RLN90481.1 - 0.0012 18.6 7.9 0.0012 18.6 7.9 2.7 2 1 0 2 2 2 1 Zinc finger, ZZ type EF-hand_8 PF13833.6 RLN90481.1 - 0.015 15.2 0.0 0.3 11.0 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain pair tRNA-synt_1c PF00749.21 RLN90482.1 - 4.9e-100 334.5 0.1 4.9e-100 334.5 0.1 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 RLN90482.1 - 1.4e-35 122.7 0.0 2.8e-35 121.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain WHEP-TRS PF00458.20 RLN90482.1 - 1.1e-14 54.2 1.0 1.1e-14 54.2 1.0 2.5 2 0 0 2 2 2 1 WHEP-TRS domain GST_C PF00043.25 RLN90482.1 - 2.1e-06 27.8 0.6 6.5e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RLN90482.1 - 1.8e-05 24.8 0.0 0.00037 20.6 0.0 2.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RLN90482.1 - 0.0029 17.6 0.8 0.0082 16.2 0.8 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 RLN90482.1 - 0.052 12.9 0.1 0.092 12.1 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Cation_efflux PF01545.21 RLN90483.1 - 4.6e-42 144.0 4.5 1.3e-41 142.5 4.5 1.7 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 RLN90483.1 - 3.7e-10 39.8 1.3 9.3e-10 38.5 1.3 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Clat_adaptor_s PF01217.20 RLN90484.1 - 3.4e-08 33.5 1.0 4.4e-08 33.2 1.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.6 RLN90484.1 - 3.2e-06 27.1 0.2 5.6e-06 26.3 0.2 1.6 1 1 0 1 1 1 1 Regulated-SNARE-like domain Mon1 PF03164.14 RLN90484.1 - 0.027 13.6 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 Trafficking protein Mon1 MAPKK1_Int PF08923.10 RLN90484.1 - 0.11 12.3 0.1 0.72 9.7 0.0 1.9 2 0 0 2 2 2 0 Mitogen-activated protein kinase kinase 1 interacting Pkinase_Tyr PF07714.17 RLN90485.1 - 1.6e-36 125.9 0.0 1.1e-23 83.8 0.0 3.4 2 2 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN90485.1 - 8.2e-31 107.3 0.0 2e-30 106.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 RLN90485.1 - 0.016 15.1 1.0 0.077 12.9 0.8 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family PH PF00169.29 RLN90485.1 - 0.025 15.1 0.1 0.048 14.2 0.1 1.5 1 0 0 1 1 1 0 PH domain Actin PF00022.19 RLN90486.1 - 3e-08 32.7 0.0 3.4e-08 32.5 0.0 1.0 1 0 0 1 1 1 1 Actin FCD PF07729.12 RLN90486.1 - 0.0041 17.5 0.1 0.0051 17.2 0.1 1.1 1 0 0 1 1 1 1 FCD domain Pkinase_Tyr PF07714.17 RLN90487.1 - 7.6e-10 38.5 0.0 1.1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN90487.1 - 1.2e-06 28.1 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Antirestrict PF03230.13 RLN90487.1 - 0.13 12.3 0.6 0.49 10.5 0.1 2.0 2 0 0 2 2 2 0 Antirestriction protein TSP_1 PF00090.19 RLN90488.1 - 6.8e-55 183.1 436.8 7.9e-05 22.8 2.5 44.9 46 0 0 46 46 46 37 Thrombospondin type 1 domain PTN_MK_C PF01091.18 RLN90488.1 - 2.2e-12 47.2 261.0 0.14 12.6 0.5 39.3 34 7 7 41 41 41 21 PTN/MK heparin-binding protein family, C-terminal domain DUF2568 PF10823.8 RLN90488.1 - 0.013 15.8 3.6 9.7 6.5 0.0 7.2 7 1 1 8 8 8 0 Protein of unknown function (DUF2568) DUF3452 PF11934.8 RLN90489.1 - 0.037 13.6 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Dynein_light PF01221.18 RLN90490.1 - 3.9e-24 84.8 0.4 4.5e-24 84.6 0.4 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 PTR2 PF00854.21 RLN90491.1 - 4.2e-58 197.1 8.5 6.6e-58 196.4 8.5 1.2 1 0 0 1 1 1 1 POT family Chordopox_A13L PF05961.11 RLN90491.1 - 0.35 11.1 0.0 0.35 11.1 0.0 2.3 2 0 0 2 2 2 0 Chordopoxvirus A13L protein DUF2157 PF09925.9 RLN90491.1 - 4.2 7.2 9.2 1.4 8.7 0.8 3.5 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) PRP38 PF03371.15 RLN90492.1 - 8.8e-55 185.2 0.0 1.1e-53 181.7 0.0 1.9 1 1 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 RLN90492.1 - 1.8 9.2 9.8 2.9 8.5 9.8 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term LpxC PF03331.13 RLN90493.1 - 1.7e-90 303.2 0.0 1.9e-90 303.1 0.0 1.0 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase DUF4403 PF14356.6 RLN90493.1 - 0.038 12.7 0.0 0.055 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4403) FYVE PF01363.21 RLN90494.1 - 1.8e-09 37.6 9.6 4.7e-09 36.3 9.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN90494.1 - 0.0013 18.9 4.8 0.0038 17.4 4.8 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger zf-RING_5 PF14634.6 RLN90494.1 - 1.7 8.7 10.2 3.9 7.5 10.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain ABC2_membrane PF01061.24 RLN90495.1 - 3e-63 213.0 78.9 8.6e-36 123.3 30.0 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN90495.1 - 1e-34 120.0 0.1 6.4e-17 62.3 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 RLN90495.1 - 8.5e-09 35.2 4.3 1e-06 28.5 0.0 3.9 3 0 0 3 3 3 1 CDR ABC transporter AAA_21 PF13304.6 RLN90495.1 - 1.1e-07 32.0 0.2 0.053 13.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN90495.1 - 2.5e-07 31.3 0.0 0.0011 19.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 RLN90495.1 - 4.7e-07 29.9 0.3 0.012 15.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 RLN90495.1 - 1.2e-06 28.2 4.6 0.013 15.2 0.9 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN90495.1 - 1.5e-05 25.3 0.0 0.044 14.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 RLN90495.1 - 8.3e-05 21.9 59.6 0.00012 21.4 19.3 3.1 2 2 0 2 2 2 2 ABC-2 family transporter protein Zeta_toxin PF06414.12 RLN90495.1 - 9.6e-05 21.7 1.2 0.0048 16.2 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 RLN90495.1 - 0.00011 21.9 1.6 0.031 13.9 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RLN90495.1 - 0.00068 20.2 1.2 0.23 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 RLN90495.1 - 0.001 18.6 1.4 2.6 7.4 0.1 3.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 RLN90495.1 - 0.0016 19.0 0.0 2.3 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RLN90495.1 - 0.002 17.9 0.2 0.76 9.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 RLN90495.1 - 0.002 18.2 0.8 0.82 9.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 RLN90495.1 - 0.0025 18.3 0.3 5.4 7.5 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RLN90495.1 - 0.0058 16.6 0.1 0.47 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) PDR_assoc PF08370.11 RLN90495.1 - 0.0067 16.1 13.3 0.01 15.5 0.0 4.0 3 0 0 3 3 3 1 Plant PDR ABC transporter associated AAA_24 PF13479.6 RLN90495.1 - 0.01 15.5 0.9 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 RLN90495.1 - 0.014 15.0 1.4 1.2 8.7 0.2 2.6 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 RLN90495.1 - 0.016 14.4 0.3 0.047 12.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Ploopntkinase3 PF18751.1 RLN90495.1 - 0.023 14.6 0.4 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 RLN90495.1 - 0.023 14.9 0.1 7.2 6.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 RLN90495.1 - 0.033 13.3 0.1 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 RLN90495.1 - 0.038 13.7 0.8 4.2 7.1 0.3 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 RLN90495.1 - 0.064 13.5 0.7 4.1 7.6 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 RLN90495.1 - 0.076 13.0 0.6 4.6 7.3 0.2 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 RLN90495.1 - 0.081 13.2 1.5 8.3 6.6 1.1 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RLN90495.1 - 0.082 13.3 0.5 9.5 6.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 RLN90495.1 - 0.17 11.8 5.4 5.9 6.8 0.2 2.6 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 RLN90495.1 - 0.48 10.8 1.3 10 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 RLN90495.1 - 2.5 7.4 4.7 11 5.4 0.1 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DDE_3 PF13358.6 RLN90496.1 - 3.1e-12 46.5 0.4 9.5e-12 44.9 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_5 PF01022.20 RLN90496.1 - 1.9e-07 30.8 0.0 0.00044 20.1 0.0 2.7 2 0 0 2 2 2 2 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 RLN90496.1 - 3.1e-05 23.4 0.2 0.00024 20.6 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 RLN90496.1 - 0.0001 22.0 0.3 0.00058 19.6 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 RLN90496.1 - 0.0014 18.9 1.5 2.3 8.5 0.0 3.1 2 0 0 2 2 2 2 Transposase HTH_Crp_2 PF13545.6 RLN90496.1 - 0.0033 17.4 0.3 0.01 15.8 0.3 1.9 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain LacI PF00356.21 RLN90496.1 - 0.0044 16.8 2.1 0.0087 15.8 0.3 2.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family MarR_2 PF12802.7 RLN90496.1 - 0.013 15.3 0.2 0.039 13.9 0.2 1.7 1 0 0 1 1 1 0 MarR family HTH_36 PF13730.6 RLN90496.1 - 0.014 15.3 0.0 0.58 10.1 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_40 PF14493.6 RLN90496.1 - 0.072 13.6 0.2 6.2 7.4 0.1 3.4 3 1 1 4 4 4 0 Helix-turn-helix domain HTH_10 PF04967.12 RLN90496.1 - 0.16 11.8 1.8 0.37 10.6 0.1 2.5 3 0 0 3 3 3 0 HTH DNA binding domain Tudor-knot PF11717.8 RLN90497.1 - 3.1e-08 33.4 0.3 2.9e-05 23.9 0.0 2.9 3 0 0 3 3 3 2 RNA binding activity-knot of a chromodomain DUF4473 PF14747.6 RLN90497.1 - 0.0015 19.1 0.9 4.4 7.9 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4473) HlyD_D4 PF16572.5 RLN90497.1 - 0.0018 18.1 6.4 0.12 12.2 0.2 3.2 3 0 0 3 3 3 2 Long alpha hairpin domain of cation efflux system protein, CusB MerR-DNA-bind PF09278.11 RLN90497.1 - 0.0077 16.7 3.6 5.1 7.7 0.0 4.2 4 1 1 5 5 5 1 MerR, DNA binding DUF4258 PF14076.6 RLN90497.1 - 0.032 14.6 0.1 9.6 6.7 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) Cu-oxidase_4 PF02578.15 RLN90497.1 - 0.14 11.8 1.7 12 5.4 0.1 2.4 2 0 0 2 2 2 0 Multi-copper polyphenol oxidoreductase laccase PTPlike_phytase PF14566.6 RLN90497.1 - 2.8 8.1 6.4 0.41 10.8 0.6 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate Ran_BP1 PF00638.18 RLN90498.1 - 0.00011 22.5 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain ABC2_membrane PF01061.24 RLN90499.1 - 1.3e-66 224.0 70.1 4.5e-37 127.5 26.7 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN90499.1 - 4.8e-34 117.8 0.1 6.1e-16 59.2 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN90499.1 - 1.3e-07 31.8 0.0 0.071 12.9 0.0 3.2 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN90499.1 - 6.7e-07 29.8 0.1 0.0042 17.5 0.0 2.6 3 0 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 RLN90499.1 - 7.8e-07 29.1 0.6 0.014 15.3 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 RLN90499.1 - 5.4e-06 26.1 4.9 0.018 14.8 0.6 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain PDR_CDR PF06422.12 RLN90499.1 - 1.2e-05 25.1 13.6 3.1e-05 23.8 0.0 4.4 4 1 1 5 5 4 1 CDR ABC transporter AAA_25 PF13481.6 RLN90499.1 - 2.3e-05 24.1 0.4 0.091 12.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RLN90499.1 - 4.1e-05 23.9 0.0 0.19 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN90499.1 - 0.00015 21.1 1.6 0.0087 15.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.6 RLN90499.1 - 0.0014 19.2 1.2 0.27 11.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RLN90499.1 - 0.0028 18.1 0.2 5.5 7.4 0.1 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 RLN90499.1 - 0.0029 17.2 1.0 0.77 9.3 0.4 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 RLN90499.1 - 0.0033 17.2 0.3 1.3 8.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RLN90499.1 - 0.0057 17.2 0.0 6.5 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RLN90499.1 - 0.0096 15.8 2.0 1.8 8.4 0.0 2.6 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.19 RLN90499.1 - 0.012 15.0 0.9 9.3 5.6 0.1 3.5 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 RLN90499.1 - 0.016 15.0 0.5 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain PDR_assoc PF08370.11 RLN90499.1 - 0.016 14.9 1.0 0.016 14.9 1.0 5.8 6 0 0 6 6 5 0 Plant PDR ABC transporter associated ABC_ATPase PF09818.9 RLN90499.1 - 0.024 13.5 1.6 3.7 6.2 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_5 PF07728.14 RLN90499.1 - 0.034 14.2 0.6 0.96 9.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 RLN90499.1 - 0.048 13.8 0.1 11 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 RLN90499.1 - 0.065 13.3 2.4 5.7 7.1 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase G-alpha PF00503.20 RLN90499.1 - 0.077 12.1 0.0 0.31 10.2 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit Roc PF08477.13 RLN90499.1 - 0.078 13.2 0.4 6.2 7.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 RLN90499.1 - 0.098 12.7 1.4 2.5 8.1 0.2 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 RLN90499.1 - 0.1 11.8 0.3 0.23 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Ploopntkinase3 PF18751.1 RLN90499.1 - 0.12 12.2 0.3 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ABC2_membrane_3 PF12698.7 RLN90499.1 - 0.17 10.9 63.5 0.27 10.3 24.1 3.4 2 2 1 3 3 2 0 ABC-2 family transporter protein AAA_19 PF13245.6 RLN90499.1 - 0.18 12.1 0.5 28 5.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 RLN90499.1 - 0.27 11.0 2.1 4.9 6.9 0.3 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC2_membrane PF01061.24 RLN90500.1 - 2.2e-66 223.3 76.9 1.9e-36 125.5 25.8 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN90500.1 - 4.1e-35 121.3 0.2 4.2e-16 59.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 RLN90500.1 - 1.6e-08 34.0 49.5 0.00015 21.0 22.2 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 RLN90500.1 - 5.2e-07 29.7 0.8 0.017 15.0 0.3 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 RLN90500.1 - 5.5e-07 29.7 0.0 0.068 13.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN90500.1 - 2.2e-06 28.1 0.3 0.044 14.2 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 RLN90500.1 - 5.7e-06 26.0 4.7 0.017 14.8 0.6 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN90500.1 - 1.1e-05 25.8 0.2 0.036 14.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 RLN90500.1 - 3e-05 23.7 0.4 0.06 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN90500.1 - 0.00011 21.5 2.0 0.0088 15.3 0.0 2.8 3 0 0 3 3 2 1 Zeta toxin PDR_CDR PF06422.12 RLN90500.1 - 0.00014 21.7 9.4 0.00049 19.9 0.0 3.8 3 1 1 4 4 4 1 CDR ABC transporter AAA PF00004.29 RLN90500.1 - 0.00058 20.3 0.3 1.7 9.1 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 RLN90500.1 - 0.0015 19.1 0.7 0.46 11.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RLN90500.1 - 0.0018 18.0 0.2 0.97 9.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 RLN90500.1 - 0.0065 16.1 1.3 0.49 10.0 0.4 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 RLN90500.1 - 0.0078 15.7 0.9 5.5 6.4 0.1 3.7 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 RLN90500.1 - 0.016 15.7 0.0 10 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RLN90500.1 - 0.019 14.7 1.2 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 RLN90500.1 - 0.019 15.0 0.3 3.4 7.7 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 RLN90500.1 - 0.027 14.6 0.1 7.4 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 RLN90500.1 - 0.027 13.6 0.4 0.061 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 RLN90500.1 - 0.029 14.5 1.9 3.6 7.7 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 RLN90500.1 - 0.03 14.3 0.6 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_5 PF07728.14 RLN90500.1 - 0.031 14.3 0.5 0.91 9.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PDR_assoc PF08370.11 RLN90500.1 - 0.043 13.6 10.2 0.35 10.6 2.2 3.5 3 0 0 3 3 2 0 Plant PDR ABC transporter associated G-alpha PF00503.20 RLN90500.1 - 0.045 12.9 0.1 0.19 10.8 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit NACHT PF05729.12 RLN90500.1 - 0.062 13.2 4.3 3.4 7.5 0.1 2.5 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 RLN90500.1 - 0.069 13.6 0.4 8.9 6.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ABC_ATPase PF09818.9 RLN90500.1 - 0.07 11.9 0.5 2.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_17 PF13207.6 RLN90500.1 - 0.079 13.4 1.1 0.78 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 RLN90500.1 - 0.11 12.8 0.8 7.1 6.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 RLN90500.1 - 0.14 11.9 1.8 5.4 6.8 0.3 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 RLN90500.1 - 0.16 11.4 1.5 0.89 9.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_19 PF13245.6 RLN90500.1 - 0.2 12.0 0.2 15 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 RLN90500.1 - 0.33 10.3 1.9 5.5 6.3 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 RLN90500.1 - 0.46 9.8 1.7 6.8 6.0 0.1 2.4 2 0 0 2 2 2 0 KaiC DUF87 PF01935.17 RLN90500.1 - 3.7 7.6 5.4 26 4.8 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain DUF4091 PF13320.6 RLN90501.1 - 4.4e-18 65.2 0.3 6.3e-18 64.7 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4091) Phage_TAC_7 PF10109.9 RLN90501.1 - 0.034 14.2 0.3 0.16 12.1 0.2 1.9 1 1 1 2 2 2 0 Phage tail assembly chaperone proteins, E, or 41 or 14 RWP-RK PF02042.15 RLN90503.1 - 5.6e-17 61.5 0.2 1.3e-16 60.2 0.2 1.7 1 0 0 1 1 1 1 RWP-RK domain KNOX2 PF03791.13 RLN90504.1 - 0.0055 16.2 0.9 0.29 10.7 0.3 2.9 2 0 0 2 2 2 1 KNOX2 domain DUF4135 PF13575.6 RLN90504.1 - 0.1 11.9 10.8 0.22 10.8 9.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4135) HMMR_N PF15905.5 RLN90504.1 - 0.91 8.9 44.6 3 7.2 2.3 3.4 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal MULE PF10551.9 RLN90505.1 - 5.1e-17 62.1 4.6 5.2e-17 62.0 0.1 3.1 3 0 0 3 3 3 1 MULE transposase domain DUF5575 PF17738.1 RLN90505.1 - 7.6e-11 41.6 1.0 2.1e-07 30.3 0.1 2.3 2 0 0 2 2 2 2 Family of unknown function (DUF5575) DDE_Tnp_ISL3 PF01610.17 RLN90505.1 - 0.0012 18.6 0.1 0.003 17.3 0.1 1.7 1 0 0 1 1 1 1 Transposase Peptidase_C48 PF02902.19 RLN90505.1 - 0.0022 17.9 0.4 0.0067 16.3 0.1 2.0 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain SP_C-Propep PF08999.10 RLN90506.1 - 0.0091 15.8 0.0 0.0097 15.7 0.0 1.1 1 0 0 1 1 1 1 Surfactant protein C, N terminal propeptide DUF5362 PF17319.2 RLN90506.1 - 0.012 15.4 0.3 0.016 15.1 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5362) SpoIIIAH PF12685.7 RLN90506.1 - 0.051 13.4 0.3 0.075 12.9 0.3 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Med13_C PF06333.12 RLN90507.1 - 9.7e-12 44.8 8.9 2.1e-06 27.3 0.1 3.2 2 2 0 3 3 3 2 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 RLN90507.1 - 2.4e-07 30.4 0.0 5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 RLN90507.1 - 3.6e-07 30.2 1.1 0.00013 21.8 0.0 3.3 2 1 0 3 3 3 2 MID domain of medPIWI Helitron_like_N PF14214.6 RLN90508.1 - 8.3e-06 26.1 3.1 2.7e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus DUF572 PF04502.13 RLN90508.1 - 1.4 8.4 17.2 2.7 7.5 17.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) V_ATPase_I PF01496.19 RLN90508.1 - 2.2 6.1 4.0 2.5 5.9 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF874 PF05917.11 RLN90508.1 - 5.5 5.9 7.5 9.3 5.2 7.5 1.3 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Aa_trans PF01490.18 RLN90509.1 - 9.8e-12 44.3 1.6 1.1e-11 44.1 1.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 RLN90509.1 - 2.6e-05 23.4 1.5 3.3e-05 23.1 1.5 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family START PF01852.19 RLN90510.1 - 8.7e-13 48.2 0.0 1.5e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 START domain Aa_trans PF01490.18 RLN90511.1 - 5.1e-48 163.8 23.9 6.3e-48 163.5 23.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Myb_DNA-binding PF00249.31 RLN90512.1 - 3.3e-13 49.6 0.3 5.3e-13 48.9 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN90512.1 - 0.00022 21.4 0.2 0.00035 20.8 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN90512.1 - 0.013 15.3 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 Myb DNA-binding like HMG_box PF00505.19 RLN90513.1 - 7.7e-66 218.5 21.7 3e-16 59.6 0.4 5.5 5 0 0 5 5 5 5 HMG (high mobility group) box HMG_box_2 PF09011.10 RLN90513.1 - 1.8e-45 153.4 25.5 1.3e-10 41.8 0.3 5.9 5 0 0 5 5 5 5 HMG-box domain HMG_box_5 PF14887.6 RLN90513.1 - 4.7e-07 29.7 18.7 0.018 15.0 0.6 6.1 6 0 0 6 6 6 3 HMG (high mobility group) box 5 COX4 PF02936.14 RLN90513.1 - 0.038 14.0 14.9 5.3 7.1 0.3 5.1 5 0 0 5 5 5 0 Cytochrome c oxidase subunit IV LPD11 PF18824.1 RLN90513.1 - 0.078 13.1 0.5 0.078 13.1 0.5 4.0 6 0 0 6 6 6 0 Large polyvalent protein-associated domain 11 Peptidase_M61 PF05299.12 RLN90513.1 - 1.6 9.1 11.9 23 5.4 0.1 4.7 5 0 0 5 5 5 0 M61 glycyl aminopeptidase EamA PF00892.20 RLN90514.1 - 0.0042 17.3 30.6 0.082 13.1 12.1 3.1 2 1 0 2 2 2 2 EamA-like transporter family bZIP_1 PF00170.21 RLN90515.1 - 0.0011 19.0 14.1 0.0011 19.0 14.1 2.3 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 RLN90515.1 - 0.0023 18.0 11.6 0.0023 18.0 11.6 3.4 3 0 0 3 3 3 1 Basic region leucine zipper Sigma70_r3 PF04539.16 RLN90515.1 - 0.075 13.1 0.1 0.075 13.1 0.1 3.2 4 0 0 4 4 4 0 Sigma-70 region 3 NPV_P10 PF05531.12 RLN90515.1 - 0.32 11.5 2.6 1.1 9.8 2.6 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein UPF0242 PF06785.11 RLN90515.1 - 0.42 10.7 13.5 0.58 10.2 8.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus LSM PF01423.22 RLN90516.1 - 1.5e-14 53.4 0.4 1.9e-14 53.1 0.4 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 RLN90516.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Hfq protein EGF_2 PF07974.13 RLN90518.1 - 0.0078 16.6 7.1 0.0078 16.6 7.1 5.5 4 0 0 4 4 4 3 EGF-like domain Apt1 PF10351.9 RLN90518.1 - 4.8 5.9 13.6 6.5 5.5 13.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4953 PF16313.5 RLN90519.1 - 8.3e-63 212.5 0.0 8.3e-63 212.5 0.0 1.6 2 0 0 2 2 2 1 Met-zincin DUF5117 PF17148.4 RLN90519.1 - 2.5e-09 37.3 0.0 1.8e-07 31.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF5117) AAA_33 PF13671.6 RLN90519.1 - 3.1e-08 33.9 0.2 2.4e-07 31.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain Reprolysin_5 PF13688.6 RLN90519.1 - 0.00039 20.6 1.6 0.0006 20.0 0.4 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12 KTI12 PF08433.10 RLN90519.1 - 0.00079 19.0 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Reprolysin_4 PF13583.6 RLN90519.1 - 0.0031 17.2 1.9 0.0057 16.3 0.1 2.1 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like AAA_22 PF13401.6 RLN90519.1 - 0.0033 17.7 0.0 0.014 15.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain Reprolysin_3 PF13582.6 RLN90519.1 - 0.0068 16.9 0.5 0.021 15.4 0.1 2.0 2 0 0 2 2 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 RLN90519.1 - 0.012 15.5 0.3 0.098 12.5 0.0 2.3 2 0 0 2 2 2 0 Matrixin Peptidase_M66 PF10462.9 RLN90519.1 - 0.015 14.3 0.2 0.025 13.5 0.2 1.3 1 0 0 1 1 1 0 Peptidase M66 AAA_18 PF13238.6 RLN90519.1 - 0.017 15.7 0.0 0.04 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Peptidase_M43 PF05572.13 RLN90519.1 - 0.019 14.9 0.1 0.041 13.8 0.1 1.6 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.6 RLN90519.1 - 0.019 14.9 0.1 0.042 13.7 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like AAA_16 PF13191.6 RLN90519.1 - 0.023 15.1 0.2 0.08 13.3 0.2 1.9 1 0 0 1 1 1 0 AAA ATPase domain Astacin PF01400.24 RLN90519.1 - 0.063 12.9 0.4 3.2 7.3 0.2 2.4 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Zeta_toxin PF06414.12 RLN90519.1 - 0.076 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin tRNA-synt_1c PF00749.21 RLN90520.1 - 2e-59 201.0 0.0 1.3e-36 126.1 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain PALP PF00291.25 RLN90522.1 - 4.1e-34 118.3 3.3 3.3e-19 69.4 0.8 4.2 3 1 0 3 3 3 3 Pyridoxal-phosphate dependent enzyme DUF3510 PF12022.8 RLN90522.1 - 3.6e-24 85.6 0.1 1.2e-23 83.8 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) COG2 PF06148.11 RLN90522.1 - 4.6e-19 68.8 5.2 4.6e-19 68.8 5.2 1.9 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Zw10 PF06248.13 RLN90522.1 - 0.0024 16.5 2.2 0.027 13.0 2.2 2.3 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Myb_DNA-bind_2 PF08914.11 RLN90522.1 - 0.084 13.1 0.1 0.45 10.7 0.0 2.3 3 0 0 3 3 3 0 Rap1 Myb domain WD40 PF00400.32 RLN90523.1 - 4.1e-13 49.6 8.4 0.00021 22.0 0.6 7.4 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN90523.1 - 0.00033 20.9 0.1 5.6 7.3 0.0 4.8 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain CALCOCO1 PF07888.11 RLN90523.1 - 0.012 14.5 62.7 0.038 12.9 7.3 3.7 2 1 2 4 4 4 0 Calcium binding and coiled-coil domain (CALCOCO1) like SlyX PF04102.12 RLN90523.1 - 0.13 12.9 0.1 0.13 12.9 0.1 7.4 5 1 3 8 8 8 0 SlyX NBD94 PF16830.5 RLN90523.1 - 4.3 7.8 6.7 48 4.4 4.3 2.8 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH LRR_8 PF13855.6 RLN90524.1 - 4.3e-12 45.6 4.7 4.4e-11 42.4 0.7 5.0 4 1 2 6 6 6 2 Leucine rich repeat LRR_4 PF12799.7 RLN90524.1 - 5.1e-08 33.1 17.5 2.7e-05 24.4 0.0 5.4 4 1 2 6 6 6 2 Leucine Rich repeats (2 copies) WW PF00397.26 RLN90524.1 - 1.2e-06 28.5 3.9 3.1e-06 27.2 3.9 1.7 1 0 0 1 1 1 1 WW domain LRR_6 PF13516.6 RLN90524.1 - 2.2e-06 27.3 15.4 0.0032 17.4 0.1 6.8 7 0 0 7 7 7 2 Leucine Rich repeat ubiquitin PF00240.23 RLN90524.1 - 5.3e-05 22.9 0.1 0.00017 21.3 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin family LRR_9 PF14580.6 RLN90524.1 - 0.00029 20.4 3.2 0.00067 19.2 3.2 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 RLN90524.1 - 0.0015 18.8 0.8 2.1e+02 3.1 0.0 5.8 5 0 0 5 5 5 0 Leucine Rich Repeat Ubiquitin_2 PF14560.6 RLN90524.1 - 0.036 14.5 0.1 0.1 13.1 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain Acetyltransf_11 PF13720.6 RLN90524.1 - 0.11 13.0 0.3 7.6 7.1 0.0 3.1 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Pkinase_Tyr PF07714.17 RLN90525.1 - 5.7e-28 97.9 0.0 1.3e-18 67.2 0.1 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN90525.1 - 1.6e-19 70.3 0.0 1.5e-17 63.8 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Cofilin_ADF PF00241.20 RLN90525.1 - 0.0097 15.7 0.0 0.27 11.0 0.0 2.5 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein Ubiquitin_2 PF14560.6 RLN90525.1 - 0.013 16.0 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain XET_C PF06955.12 RLN90526.1 - 0.12 12.2 1.2 0.17 11.7 1.2 1.3 1 0 0 1 1 1 0 Xyloglucan endo-transglycosylase (XET) C-terminus HemY_N PF07219.13 RLN90526.1 - 0.14 12.4 1.8 0.18 12.0 1.8 1.1 1 0 0 1 1 1 0 HemY protein N-terminus LapA_dom PF06305.11 RLN90526.1 - 0.39 10.6 5.7 0.67 9.8 5.7 1.5 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Neurochondrin PF05536.11 RLN90527.1 - 3.7e-26 91.7 2.6 7e-26 90.8 2.1 1.6 2 0 0 2 2 2 1 Neurochondrin zf-RING_2 PF13639.6 RLN90528.1 - 5.1e-10 39.5 12.2 8.4e-10 38.8 12.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN90528.1 - 4.7e-08 32.7 13.3 7.8e-08 32.0 13.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN90528.1 - 8.8e-07 29.1 13.6 4.2e-06 27.0 13.6 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RLN90528.1 - 2.1e-05 24.3 12.8 3.9e-05 23.4 12.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 RLN90528.1 - 0.00013 22.0 5.2 0.00022 21.3 5.2 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_3 PF13920.6 RLN90528.1 - 0.00031 20.6 9.7 0.00047 20.0 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN90528.1 - 0.00073 19.5 8.6 0.0016 18.4 8.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 RLN90528.1 - 0.0023 17.5 8.5 0.0046 16.5 8.5 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 RLN90528.1 - 0.0023 17.9 4.1 0.0045 17.0 4.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 RLN90528.1 - 0.0041 16.8 7.3 0.0041 16.8 7.3 2.0 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_5 PF14634.6 RLN90528.1 - 0.01 15.8 10.8 0.017 15.1 10.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RLN90528.1 - 0.094 12.6 9.9 0.18 11.7 9.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 UPF0547 PF10571.9 RLN90528.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 FANCL_C PF11793.8 RLN90528.1 - 0.13 12.4 7.5 0.66 10.2 7.5 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 RLN90528.1 - 1.1 9.6 9.5 2.1 8.7 9.5 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 RLN90528.1 - 3.5 7.8 10.1 7.9 6.7 10.1 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 RLN90528.1 - 8.5 6.3 9.0 34 4.3 9.2 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Mito_carr PF00153.27 RLN90529.1 - 4.1e-32 110.0 1.4 5.4e-25 87.1 0.2 2.0 1 1 1 2 2 2 2 Mitochondrial carrier protein MMR_HSR1_Xtn PF16897.5 RLN90530.1 - 3.6e-37 126.6 0.1 5.1e-37 126.1 0.1 1.2 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 RLN90530.1 - 3e-10 40.2 0.0 5.7e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 RLN90530.1 - 0.0014 18.7 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 Dynamin family Glycos_transf_2 PF00535.26 RLN90530.1 - 0.014 15.2 0.2 0.024 14.4 0.2 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 TGS PF02824.21 RLN90531.1 - 6.7e-08 32.5 0.0 9.2e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 TGS domain AMP-binding PF00501.28 RLN90532.1 - 7.4e-19 67.6 0.3 1.2e-18 66.9 0.3 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN90532.1 - 0.00015 22.7 0.0 0.00032 21.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain T2SS-T3SS_pil_N PF13629.6 RLN90532.1 - 0.098 12.4 0.3 0.43 10.4 0.0 2.2 2 0 0 2 2 2 0 Pilus formation protein N terminal region TTL PF03133.15 RLN90533.1 - 3.1e-53 180.8 0.0 4.1e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RLN90533.1 - 1.3e-06 27.9 0.0 0.0042 16.4 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 RLN90533.1 - 0.0018 18.4 0.0 0.23 11.5 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp domain Vps51 PF08700.11 RLN90534.1 - 0.0017 18.4 0.7 0.005 16.9 0.1 2.1 2 0 0 2 2 2 1 Vps51/Vps67 aGPT-Pplase1 PF18723.1 RLN90535.1 - 4.1e-11 42.8 0.5 8.8e-11 41.8 0.2 1.6 1 1 1 2 2 2 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 PHD PF00628.29 RLN90535.1 - 8.8e-10 38.3 8.1 8.8e-10 38.3 8.1 2.4 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.6 RLN90535.1 - 7.5e-05 22.2 2.3 7.5e-05 22.2 2.3 2.4 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 RLN90535.1 - 0.0024 17.8 1.6 0.0024 17.8 1.6 3.4 5 0 0 5 5 5 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 RLN90535.1 - 0.0085 15.7 1.3 0.0085 15.7 1.3 2.2 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain C1_2 PF03107.16 RLN90535.1 - 0.32 11.4 11.5 0.14 12.5 3.4 4.0 4 0 0 4 4 4 0 C1 domain DUF2116 PF09889.9 RLN90535.1 - 0.8 9.7 10.5 0.82 9.7 0.2 3.6 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) PHD_4 PF16866.5 RLN90535.1 - 1.8 8.7 22.3 4.8 7.3 10.5 4.0 3 1 0 3 3 3 0 PHD-finger zf-RING_9 PF13901.6 RLN90535.1 - 2.5 8.1 13.4 0.2 11.6 5.5 2.6 2 1 0 2 2 2 0 Putative zinc-RING and/or ribbon C1_1 PF00130.22 RLN90535.1 - 2.6 8.0 10.1 0.23 11.3 2.2 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TAL_FSA PF00923.19 RLN90536.1 - 2.2e-102 342.3 0.1 2.6e-102 342.1 0.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase WD40 PF00400.32 RLN90537.1 - 1.2e-05 26.0 0.1 0.0098 16.7 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat eIF2A PF08662.11 RLN90537.1 - 0.12 12.2 0.0 4.6 7.1 0.0 2.8 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A PIP5K PF01504.18 RLN90538.1 - 2e-44 151.9 0.0 5.4e-36 124.2 0.1 2.4 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 RLN90538.1 - 1.1e-22 80.3 0.1 4.1e-22 78.5 0.1 1.8 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-FPG_IleRS PF06827.14 RLN90539.1 - 0.96 9.4 6.6 0.3 11.0 2.7 2.0 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Herpes_pp85 PF04637.12 RLN90539.1 - 1.4 7.3 3.3 1.7 7.0 3.3 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Tnp_zf-ribbon_2 PF13842.6 RLN90539.1 - 2.6 8.9 9.1 4.6 8.1 9.1 1.4 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon ABC2_membrane PF01061.24 RLN90541.1 - 4e-34 117.9 31.9 5.6e-34 117.4 31.9 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 RLN90541.1 - 6e-08 32.2 18.9 6e-08 32.2 18.9 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein PDR_CDR PF06422.12 RLN90541.1 - 1.8e-05 24.6 0.0 1.8e-05 24.6 0.0 3.2 4 0 0 4 4 4 1 CDR ABC transporter Pectate_lyase PF03211.13 RLN90542.1 - 3.5e-17 62.6 0.0 5e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Pectate lyase MFS_1 PF07690.16 RLN90543.1 - 2.7e-23 82.5 26.2 2.3e-17 63.0 9.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN90543.1 - 5.9e-07 28.7 3.0 5.9e-07 28.7 3.0 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 RLN90543.1 - 0.00022 20.2 0.0 0.0011 17.9 0.0 2.3 1 1 0 1 1 1 1 MFS_1 like family NHL PF01436.21 RLN90546.1 - 2.9e-13 49.1 6.5 2.4e-05 24.1 0.0 5.8 7 0 0 7 7 7 3 NHL repeat DUF5128 PF17170.4 RLN90546.1 - 4.5e-05 22.8 0.0 0.091 11.9 0.0 3.2 2 1 1 3 3 3 3 6-bladed beta-propeller Phytase-like PF13449.6 RLN90546.1 - 0.0013 18.8 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Esterase-like activity of phytase SGL PF08450.12 RLN90546.1 - 0.0077 15.8 0.0 8.6 5.9 0.0 3.1 3 0 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region CDC45 PF02724.14 RLN90547.1 - 9.7e-177 589.1 0.1 1.1e-176 588.9 0.1 1.0 1 0 0 1 1 1 1 CDC45-like protein PCMT PF01135.19 RLN90548.1 - 5.4e-35 121.0 0.0 6.7e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 RLN90548.1 - 2.4e-05 25.0 0.0 4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 RLN90548.1 - 0.00058 19.9 0.0 0.00083 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN90548.1 - 0.00059 19.7 0.0 0.00072 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN90548.1 - 0.0025 18.4 0.0 0.0037 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 RLN90548.1 - 0.0086 15.2 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 RLN90548.1 - 0.03 13.9 0.0 0.042 13.4 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 RLN90548.1 - 0.038 13.8 0.0 0.062 13.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 RLN90548.1 - 0.085 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DREV PF05219.12 RLN90548.1 - 0.16 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_9 PF08003.11 RLN90548.1 - 0.24 10.3 0.1 1.1 8.1 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) DUF4833 PF16117.5 RLN90550.1 - 3.8e-41 140.3 0.0 4.7e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4833) PCMT PF01135.19 RLN90551.1 - 1.5e-46 158.8 0.0 1.7e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 RLN90551.1 - 1.3e-05 25.8 0.0 1.9e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 RLN90551.1 - 2.6e-05 24.3 0.0 3.6e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN90551.1 - 4.1e-05 23.4 0.0 5.6e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN90551.1 - 0.00033 21.2 0.1 0.00053 20.6 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN90551.1 - 0.0019 18.0 0.0 0.0026 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN90551.1 - 0.0088 15.6 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 RLN90551.1 - 0.045 13.7 0.0 0.06 13.3 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 RLN90551.1 - 0.052 13.7 0.0 0.074 13.2 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 RLN90551.1 - 0.059 12.8 0.0 0.079 12.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AviRa PF11599.8 RLN90551.1 - 0.085 12.3 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_9 PF08003.11 RLN90551.1 - 0.13 11.1 0.0 0.3 10.0 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 RLN90551.1 - 0.21 10.9 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 RLN90551.1 - 0.24 10.4 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Osmo_CC PF08946.10 RLN90553.1 - 0.017 15.3 0.2 0.017 15.3 0.2 3.1 3 1 1 4 4 4 0 Osmosensory transporter coiled coil TMP_2 PF06791.13 RLN90553.1 - 0.051 13.2 7.3 0.86 9.2 1.1 2.2 2 0 0 2 2 2 0 Prophage tail length tape measure protein Spectrin PF00435.21 RLN90553.1 - 0.88 10.1 9.0 0.56 10.7 0.8 3.0 3 0 0 3 3 3 0 Spectrin repeat Pkinase_Tyr PF07714.17 RLN90555.1 - 1.8e-54 184.8 0.0 2.6e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN90555.1 - 5.8e-46 157.0 0.0 9e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LisH_TPL PF17814.1 RLN90556.1 - 0.24 11.1 0.8 1.6 8.4 0.7 2.2 2 0 0 2 2 2 0 LisH-like dimerisation domain NPR2 PF06218.11 RLN90557.1 - 1.1e-14 54.1 0.0 1.2e-14 53.9 0.0 1.0 1 0 0 1 1 1 1 Nitrogen permease regulator 2 GCD14 PF08704.10 RLN90558.1 - 3.3 7.3 6.4 11 5.6 6.4 1.8 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit INTS5_C PF14838.6 RLN90559.1 - 3.5e-13 49.1 1.4 1.1e-09 37.5 0.1 3.4 3 0 0 3 3 3 3 Integrator complex subunit 5 C-terminus WD40 PF00400.32 RLN90560.1 - 6.5e-13 49.0 13.2 0.07 14.0 0.0 9.9 11 0 0 11 11 11 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN90560.1 - 9.9e-07 29.0 0.0 2.2 8.6 0.0 5.7 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nuf2 PF03800.14 RLN90561.1 - 1e-42 145.6 0.6 3.4e-42 143.9 0.0 2.1 3 0 0 3 3 3 1 Nuf2 family DHR10 PF18595.1 RLN90561.1 - 2.9e-17 62.8 15.1 2.9e-17 62.8 15.1 4.1 1 1 3 4 4 4 1 Designed helical repeat protein 10 domain BLOC1_2 PF10046.9 RLN90561.1 - 0.078 13.3 18.2 0.081 13.2 0.5 4.5 2 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 RLN90561.1 - 0.15 12.1 4.6 2.6 8.1 1.8 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TSC22 PF01166.18 RLN90561.1 - 0.49 10.7 8.4 0.55 10.6 0.1 3.7 3 0 0 3 3 3 0 TSC-22/dip/bun family EzrA PF06160.12 RLN90561.1 - 2.9 6.0 28.2 1.3 7.1 6.6 2.8 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA GAS PF13851.6 RLN90561.1 - 8.2 5.7 40.7 1.1 8.6 10.2 3.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding ABC2_membrane PF01061.24 RLN90562.1 - 3.5e-66 222.6 80.3 2.2e-36 125.3 28.2 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN90562.1 - 7.4e-17 62.1 0.0 1.1e-16 61.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 RLN90562.1 - 1.9e-06 27.3 53.5 1.7e-05 24.1 20.4 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 RLN90562.1 - 1.8e-05 24.7 0.0 0.058 13.2 0.0 2.7 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system PDR_CDR PF06422.12 RLN90562.1 - 2.3e-05 24.2 0.0 2.3e-05 24.2 0.0 3.8 5 0 0 5 5 4 2 CDR ABC transporter PDR_assoc PF08370.11 RLN90562.1 - 0.00017 21.3 2.1 0.00017 21.3 2.1 3.5 4 0 0 4 4 3 1 Plant PDR ABC transporter associated RsgA_GTPase PF03193.16 RLN90562.1 - 0.0027 17.7 0.2 0.0052 16.7 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN90562.1 - 0.0083 15.9 1.3 0.019 14.7 1.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Comm PF15957.5 RLN90562.1 - 0.015 15.7 0.0 0.05 13.9 0.0 1.9 1 0 0 1 1 1 0 Commissureless AAA_23 PF13476.6 RLN90562.1 - 0.028 14.9 0.3 0.078 13.5 0.4 1.6 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 RLN90562.1 - 0.14 11.6 0.1 2.4 7.5 0.1 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RLN90562.1 - 0.15 12.4 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 RLN90562.1 - 0.24 10.9 0.5 0.54 9.8 0.5 1.5 1 0 0 1 1 1 0 AAA domain BLACT_WH PF17778.1 RLN90563.1 - 0.078 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain Biotin_lipoyl_2 PF13533.6 RLN90563.1 - 1 9.2 2.9 4.2 7.3 0.1 2.5 3 0 0 3 3 3 0 Biotin-lipoyl like Cadherin_4 PF17803.1 RLN90564.1 - 0.0051 17.4 24.4 0.11 13.1 0.2 7.2 8 0 0 8 8 8 2 Bacterial cadherin-like domain Big_9 PF17963.1 RLN90564.1 - 0.21 12.3 21.3 4.5 8.1 0.1 8.8 7 1 1 8 8 8 0 Bacterial Ig domain Pkinase_Tyr PF07714.17 RLN90566.1 - 5.3e-30 104.6 0.0 8e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN90566.1 - 3.4e-20 72.5 0.0 4.7e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF1180 PF06679.12 RLN90566.1 - 0.0001 22.7 0.3 0.00024 21.6 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) TMEM154 PF15102.6 RLN90566.1 - 0.0052 16.7 0.0 0.0092 15.9 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family Orf78 PF06024.12 RLN90566.1 - 0.031 14.6 0.0 0.058 13.7 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) DUF4083 PF13314.6 RLN90566.1 - 0.038 14.0 2.3 0.079 12.9 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Peptidase_M56 PF05569.11 RLN90566.1 - 0.13 11.4 0.2 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 BlaR1 peptidase M56 SARAF PF06682.12 RLN90566.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Amnionless PF14828.6 RLN90566.1 - 0.18 10.6 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Amnionless ASFV_J13L PF05568.11 RLN90566.1 - 0.26 11.0 3.5 0.32 10.7 2.4 1.7 1 1 0 1 1 1 0 African swine fever virus J13L protein YebO PF13974.6 RLN90566.1 - 3.5 7.8 4.7 7.6 6.7 4.7 1.5 1 0 0 1 1 1 0 YebO-like protein DUF3149 PF11346.8 RLN90566.1 - 3.8 7.2 10.3 7.2 6.3 10.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Ank_2 PF12796.7 RLN90567.1 - 7.3e-80 263.6 35.8 1.4e-14 54.4 0.3 8.5 3 3 6 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.30 RLN90567.1 - 1.6e-55 183.2 34.5 2.6e-06 27.6 0.5 13.5 12 1 1 13 13 13 11 Ankyrin repeat Ank_3 PF13606.6 RLN90567.1 - 3.3e-49 159.1 16.8 0.00027 21.1 0.0 15.2 16 0 0 16 16 16 10 Ankyrin repeat Ank_5 PF13857.6 RLN90567.1 - 7.9e-48 159.9 34.1 7e-06 26.2 0.3 13.7 5 5 10 15 15 15 13 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN90567.1 - 2e-45 152.6 20.8 7.1e-07 29.7 0.1 11.1 6 5 6 12 12 12 12 Ankyrin repeats (many copies) Ribosomal_S11 PF00411.19 RLN90567.1 - 0.047 14.1 6.7 0.39 11.1 1.7 3.3 2 0 0 2 2 2 0 Ribosomal protein S11 WW PF00397.26 RLN90568.1 - 0.0092 16.1 0.4 0.53 10.4 0.0 2.6 2 0 0 2 2 2 2 WW domain Seipin PF06775.14 RLN90569.1 - 4.9e-51 173.6 1.8 7.5e-51 173.0 1.8 1.3 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) MtN3_slv PF03083.16 RLN90569.1 - 2 8.5 5.5 0.37 10.9 1.0 1.9 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF4407 PF14362.6 RLN90571.1 - 0.6 9.4 5.2 0.99 8.7 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4050 PF13259.6 RLN90571.1 - 7.6 6.8 7.8 17 5.7 7.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) Tir_receptor_C PF07489.11 RLN90572.1 - 0.17 11.8 0.1 0.25 11.3 0.1 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Zip PF02535.22 RLN90573.1 - 3.7e-16 59.3 7.2 4.4e-16 59.0 7.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter LEP503 PF15221.6 RLN90573.1 - 0.0049 17.2 0.0 0.0087 16.4 0.0 1.4 1 0 0 1 1 1 1 Lens epithelial cell protein LEP503 Dynamin_N PF00350.23 RLN90576.1 - 0.0017 18.4 1.4 0.0028 17.8 1.3 1.4 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 RLN90576.1 - 0.02 15.0 0.1 0.034 14.2 0.1 1.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 RLN90576.1 - 0.021 14.6 0.1 0.028 14.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain PPR_2 PF13041.6 RLN90577.1 - 4.7e-31 106.7 17.1 0.0065 16.6 0.0 14.9 5 4 11 16 16 16 10 PPR repeat family PPR_3 PF13812.6 RLN90577.1 - 5.7e-28 96.8 10.4 0.004 17.2 0.0 13.1 8 4 9 17 17 16 8 Pentatricopeptide repeat domain PPR PF01535.20 RLN90577.1 - 2.7e-24 83.7 22.1 0.31 11.4 0.0 16.4 18 0 0 18 18 18 7 PPR repeat PPR_long PF17177.4 RLN90577.1 - 1.6e-23 83.2 15.3 1.7e-07 30.9 0.1 6.0 1 1 4 6 6 6 6 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 RLN90577.1 - 7.1e-05 22.4 0.4 0.91 9.3 0.0 5.5 6 0 0 6 6 6 1 PPR repeat COX5A PF02284.16 RLN90577.1 - 7.9e-05 22.6 1.7 1.1 9.3 0.0 4.9 5 0 0 5 5 5 1 Cytochrome c oxidase subunit Va Self-incomp_S1 PF05938.11 RLN90577.1 - 0.0088 16.6 3.0 18 5.9 0.1 4.1 4 0 0 4 4 4 0 Plant self-incompatibility protein S1 RPM2 PF08579.11 RLN90577.1 - 0.017 15.5 3.4 5.6 7.4 0.1 5.3 3 3 2 6 6 6 0 Mitochondrial ribonuclease P subunit (RPM2) RPAP3_C PF13877.6 RLN90577.1 - 0.024 15.2 4.3 28 5.3 0.0 6.0 7 0 0 7 7 7 0 Potential Monad-binding region of RPAP3 DUF5599 PF18141.1 RLN90577.1 - 0.033 14.4 0.2 15 5.9 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5599) Mic1 PF07035.12 RLN90577.1 - 0.079 12.7 13.1 15 5.3 0.1 6.2 6 1 0 7 7 7 0 Colon cancer-associated protein Mic1-like P16-Arc PF04699.14 RLN90577.1 - 0.24 11.9 3.7 24 5.4 0.1 4.8 3 3 2 5 5 5 0 ARP2/3 complex 16 kDa subunit (p16-Arc) ABC2_membrane PF01061.24 RLN90578.1 - 1.3e-66 224.0 68.5 7.5e-38 130.1 23.8 2.6 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN90578.1 - 1.2e-33 116.6 0.2 7.5e-16 58.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 RLN90578.1 - 1.7e-09 37.3 40.5 5.3e-07 29.1 9.3 3.0 2 2 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 RLN90578.1 - 1.9e-08 34.4 0.6 0.0072 16.2 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 RLN90578.1 - 1.9e-07 31.2 0.1 0.06 13.1 0.0 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN90578.1 - 9.1e-07 29.4 0.4 0.011 16.1 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 RLN90578.1 - 1.3e-05 24.9 6.7 0.02 14.6 1.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain PDR_CDR PF06422.12 RLN90578.1 - 2.1e-05 24.3 9.2 0.00088 19.1 0.0 4.3 4 0 0 4 4 4 1 CDR ABC transporter AAA_22 PF13401.6 RLN90578.1 - 3.1e-05 24.3 0.0 0.066 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 RLN90578.1 - 3.4e-05 23.5 1.3 0.097 12.2 0.2 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN90578.1 - 3.6e-05 23.1 0.7 0.0047 16.2 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.6 RLN90578.1 - 0.0004 21.0 1.0 0.22 12.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RLN90578.1 - 0.0015 18.3 0.3 0.68 9.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 RLN90578.1 - 0.0016 17.9 1.2 0.97 8.8 0.2 3.4 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 RLN90578.1 - 0.002 18.5 0.1 5.5 7.4 0.1 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 RLN90578.1 - 0.0034 17.1 0.2 1.1 9.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RLN90578.1 - 0.0056 17.2 0.0 4.8 7.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 RLN90578.1 - 0.0067 16.0 1.3 1.2 8.7 0.5 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 RLN90578.1 - 0.008 16.3 1.8 1.1 9.4 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_ATPase PF09818.9 RLN90578.1 - 0.0089 14.9 0.5 1.2 7.8 0.0 2.3 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_33 PF13671.6 RLN90578.1 - 0.012 15.8 0.1 4.7 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 RLN90578.1 - 0.015 14.4 0.6 0.046 12.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Roc PF08477.13 RLN90578.1 - 0.041 14.1 0.8 2.8 8.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 RLN90578.1 - 0.041 13.0 0.2 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit PDR_assoc PF08370.11 RLN90578.1 - 0.052 13.3 9.0 0.12 12.1 1.4 3.6 3 0 0 3 3 3 0 Plant PDR ABC transporter associated TsaE PF02367.17 RLN90578.1 - 0.06 13.3 0.9 3.2 7.8 0.2 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 RLN90578.1 - 0.069 13.1 4.1 3.9 7.4 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 RLN90578.1 - 0.078 13.3 0.4 13 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 RLN90578.1 - 0.083 12.6 1.8 3.7 7.3 0.3 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ploopntkinase3 PF18751.1 RLN90578.1 - 0.14 12.1 0.1 2 8.3 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_5 PF07728.14 RLN90578.1 - 0.15 12.0 2.4 0.8 9.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 RLN90578.1 - 0.36 11.1 2.1 37 4.5 1.3 2.7 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.23 RLN90579.1 - 8.1e-53 179.8 3.2 1.2e-52 179.2 3.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN90579.1 - 8.5e-05 23.1 0.1 0.00015 22.3 0.1 1.4 1 0 0 1 1 1 1 ABC transporter DUF2207 PF09972.9 RLN90579.1 - 0.068 11.9 1.5 0.19 10.4 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) AAA_29 PF13555.6 RLN90579.1 - 0.14 12.0 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain UPF0542 PF15086.6 RLN90579.1 - 0.19 11.7 0.1 0.42 10.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 RNA_pol_Rpc34 PF05158.12 RLN90580.1 - 0.14 11.5 0.2 0.22 10.9 0.2 1.3 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit S_100 PF01023.19 RLN90581.1 - 0.033 13.9 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain EF-hand_6 PF13405.6 RLN90581.1 - 0.1 12.6 0.0 4.7 7.4 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain Vps39_1 PF10366.9 RLN90582.1 - 2.4 8.5 4.4 1 9.7 0.5 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 DENN PF02141.21 RLN90583.1 - 1.3e-16 61.1 0.6 1.5e-16 60.9 0.6 1.1 1 0 0 1 1 1 1 DENN (AEX-3) domain SNARE_assoc PF09335.11 RLN90584.1 - 1.1e-18 67.9 11.5 1.1e-18 67.9 8.4 2.1 2 0 0 2 2 2 1 SNARE associated Golgi protein MFS_2 PF13347.6 RLN90585.1 - 2e-26 92.5 31.0 1.8e-21 76.2 6.5 2.6 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1 PF07690.16 RLN90585.1 - 2.1e-13 49.9 30.7 2e-12 46.7 30.1 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily LacY_symp PF01306.19 RLN90585.1 - 3.4e-05 22.8 0.2 3.4e-05 22.8 0.2 2.1 2 0 0 2 2 2 1 LacY proton/sugar symporter zf-SNAP50_C PF12251.8 RLN90586.1 - 1.1e-46 159.0 0.1 1.6e-46 158.5 0.1 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal GMC_oxred_C PF05199.13 RLN90586.1 - 5.2e-20 72.4 0.8 5.2e-20 72.4 0.8 2.3 2 1 0 2 2 2 1 GMC oxidoreductase Nop53 PF07767.11 RLN90586.1 - 0.23 10.8 10.6 0.48 9.8 10.6 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Toprim_3 PF13362.6 RLN90586.1 - 0.38 11.2 2.5 19 5.7 0.1 2.6 2 0 0 2 2 2 0 Toprim domain CDC45 PF02724.14 RLN90586.1 - 3.8 5.7 6.3 5.7 5.1 6.3 1.2 1 0 0 1 1 1 0 CDC45-like protein GMC_oxred_N PF00732.19 RLN90587.1 - 5.7e-41 140.8 0.0 3e-32 112.2 0.0 2.0 2 0 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 RLN90587.1 - 0.00022 21.4 0.0 0.00047 20.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 RLN90587.1 - 0.0051 15.6 0.3 0.011 14.5 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 RLN90587.1 - 0.0063 16.1 0.1 0.092 12.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RLN90587.1 - 0.0068 15.7 0.0 0.049 12.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RLN90587.1 - 0.014 14.5 0.1 0.02 14.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 RLN90587.1 - 0.019 13.9 0.0 0.025 13.5 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 RLN90587.1 - 0.019 14.2 0.0 0.037 13.3 0.0 1.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RLN90587.1 - 0.021 14.1 0.2 0.029 13.6 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 RLN90587.1 - 0.038 13.2 0.1 0.07 12.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 RLN90587.1 - 0.062 12.4 0.1 0.8 8.7 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Tubulin PF00091.25 RLN90588.1 - 1.2e-63 214.9 0.0 1.5e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RLN90588.1 - 8.4e-43 145.5 0.1 1.3e-42 145.0 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RLN90588.1 - 0.017 14.8 0.0 0.042 13.5 0.0 1.6 2 0 0 2 2 2 0 Tubulin domain cNMP_binding PF00027.29 RLN90590.1 - 5.8e-13 48.7 0.0 1.1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN90590.1 - 2.2e-05 23.8 3.3 3.8e-05 23.0 3.3 1.3 1 0 0 1 1 1 1 Ion transport protein SNF2_N PF00176.23 RLN90591.1 - 2.1e-57 194.4 0.1 3.6e-57 193.7 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN90591.1 - 1.2e-19 70.7 0.0 6.7e-19 68.3 0.0 2.3 2 1 1 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 RLN90591.1 - 1.4e-09 37.5 0.0 3.3e-05 23.2 0.0 2.7 2 1 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 GREB1 PF15782.5 RLN90591.1 - 0.52 7.4 9.3 0.78 6.8 9.3 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PX PF00787.24 RLN90592.1 - 6e-07 29.4 0.1 1.1e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 PX domain YL1 PF05764.13 RLN90592.1 - 0.28 11.3 6.5 0.38 10.9 6.5 1.1 1 0 0 1 1 1 0 YL1 nuclear protein RNase_HII PF01351.18 RLN90593.1 - 1.9e-29 102.9 0.1 4.7e-29 101.6 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease HII PX PF00787.24 RLN90593.1 - 3.4e-19 68.9 0.0 8.5e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 PX domain Peptidase_C92 PF05708.12 RLN90593.1 - 4e-06 27.0 0.0 2e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family PH PF00169.29 RLN90593.1 - 0.036 14.6 0.0 0.12 12.9 0.0 1.9 1 0 0 1 1 1 0 PH domain Ribosomal_L18A PF01775.17 RLN90595.1 - 0.054 13.6 0.2 0.083 13.0 0.2 1.3 1 0 0 1 1 1 0 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A FCH PF00611.23 RLN90596.1 - 8.4e-05 22.8 0.3 8.4e-05 22.8 0.3 2.5 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Abhydrolase_6 PF12697.7 RLN90597.1 - 0.0049 17.5 0.0 0.007 17.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 RLN90597.1 - 0.041 13.6 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein PGAP1 PF07819.13 RLN90598.1 - 0.012 15.3 0.5 0.037 13.7 0.5 1.8 1 1 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 RLN90598.1 - 0.035 13.6 0.5 0.097 12.2 0.5 1.7 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 RLN90598.1 - 0.054 14.1 0.3 0.12 12.9 0.3 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN90598.1 - 0.25 10.6 0.5 0.6 9.3 0.5 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 PHO4 PF01384.20 RLN90599.1 - 1.7e-15 56.9 9.2 1.9e-15 56.8 9.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family FSIP1 PF15554.6 RLN90600.1 - 2.4 7.2 15.4 0.77 8.8 7.6 2.9 2 1 0 2 2 2 0 FSIP1 family TsaE PF02367.17 RLN90601.1 - 1.3e-20 73.6 0.0 1.5e-20 73.4 0.0 1.0 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoLip_ATPase_C PF16212.5 RLN90603.1 - 3.4e-65 220.3 24.9 3.4e-65 220.3 24.9 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RLN90603.1 - 1.9e-21 75.5 0.0 8.3e-21 73.5 0.0 2.1 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 RLN90603.1 - 5.4e-10 39.2 0.0 7.8e-09 35.5 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RLN90603.1 - 4.6e-09 36.9 0.2 0.0028 18.0 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RLN90603.1 - 4.8e-05 23.0 0.0 0.00027 20.5 0.0 2.2 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RLN90603.1 - 0.0027 17.5 0.2 0.0097 15.7 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF5313 PF17240.2 RLN90603.1 - 0.021 15.3 0.2 0.074 13.5 0.2 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5313) Methyltransf_32 PF13679.6 RLN90605.1 - 0.046 13.7 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain FA_desaturase PF00487.24 RLN90605.1 - 0.11 12.3 0.3 0.21 11.4 0.3 1.3 1 0 0 1 1 1 0 Fatty acid desaturase TPR_1 PF00515.28 RLN90606.1 - 5.4e-20 70.3 10.5 1.6e-05 24.5 0.5 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 RLN90606.1 - 1.7e-18 65.2 15.5 4.6e-05 23.2 1.5 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 RLN90606.1 - 5.8e-18 64.3 6.8 3e-05 23.6 0.0 5.5 3 1 2 5 5 5 5 TPR repeat TPR_14 PF13428.6 RLN90606.1 - 1.9e-17 62.5 21.9 1.2e-05 25.7 0.5 6.1 2 2 4 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 RLN90606.1 - 2.2e-17 61.8 6.3 0.00011 22.1 0.4 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 RLN90606.1 - 5.7e-17 62.1 23.5 1.3e-05 25.7 1.2 4.7 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 RLN90606.1 - 5.4e-11 42.6 27.9 4.6e-07 30.0 5.5 4.5 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 RLN90606.1 - 4.5e-10 39.2 2.7 0.011 16.0 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN90606.1 - 1.6e-08 34.9 13.4 0.00021 21.7 1.0 4.0 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 RLN90606.1 - 2.6e-08 34.0 10.1 0.026 15.1 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN90606.1 - 1.1e-06 28.3 14.4 0.03 14.4 0.0 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN90606.1 - 3.2e-05 24.0 14.2 0.023 14.8 2.4 4.5 3 2 1 4 4 4 2 Tetratricopeptide repeat DUF3856 PF12968.7 RLN90606.1 - 0.0009 19.3 6.5 0.049 13.7 0.3 3.3 1 1 1 3 3 3 1 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 RLN90606.1 - 0.017 15.3 7.8 0.03 14.6 0.2 3.3 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 RLN90606.1 - 0.1 13.3 1.2 0.1 13.3 1.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN90606.1 - 0.81 9.6 22.5 2.3 8.2 1.5 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 RLN90606.1 - 1.5 9.2 9.7 1.9 8.9 0.4 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat PCMT PF01135.19 RLN90607.1 - 1.5e-60 204.6 0.0 2e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 RLN90607.1 - 0.00041 20.4 0.0 0.0007 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN90607.1 - 0.0021 17.8 0.0 0.0057 16.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN90607.1 - 0.068 13.9 0.1 0.17 12.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Chromo_shadow PF01393.19 RLN90607.1 - 0.074 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Chromo shadow domain Methyltransf_23 PF13489.6 RLN90607.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Mito_carr PF00153.27 RLN90608.1 - 6.1e-69 228.0 1.4 1.7e-23 82.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 RLN90608.1 - 0.061 12.5 0.8 0.28 10.3 0.2 2.4 1 1 2 3 3 3 0 Gammaproteobacterial serine protease DUF5366 PF17328.2 RLN90608.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5366) Aminotran_5 PF00266.19 RLN90609.1 - 3.1e-28 98.8 0.0 4.4e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 RLN90609.1 - 0.0042 15.7 0.0 0.0067 15.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pkinase PF00069.25 RLN90610.1 - 3.3e-72 243.0 0.0 5.2e-72 242.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90610.1 - 9e-37 126.8 0.0 1.5e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 RLN90610.1 - 5.3e-15 55.6 0.5 2.2e-06 28.0 0.0 4.4 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_8 PF13833.6 RLN90610.1 - 7e-13 48.2 0.8 3.7e-06 26.7 0.1 3.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 RLN90610.1 - 6.7e-12 44.1 0.6 8.2e-06 25.0 0.3 4.6 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 RLN90610.1 - 5.7e-10 38.3 1.5 0.5 10.4 0.1 5.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 RLN90610.1 - 7.6e-05 22.0 0.0 0.0074 15.7 0.1 3.4 3 0 0 3 3 3 1 EF hand Kdo PF06293.14 RLN90610.1 - 0.0019 17.6 0.1 0.0038 16.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN90610.1 - 0.0041 17.1 0.2 0.73 9.7 0.2 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family TBPIP PF07106.13 RLN90611.1 - 7.7e-21 73.8 0.2 1.6e-20 72.8 0.2 1.6 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 RLN90611.1 - 0.0001 22.4 0.4 0.00036 20.6 0.0 2.3 2 0 0 2 2 2 1 Leucine zipper with capping helix domain YL1 PF05764.13 RLN90611.1 - 0.00015 22.0 11.9 0.00015 22.0 11.9 1.8 1 1 0 2 2 2 1 YL1 nuclear protein Penicillinase_R PF03965.16 RLN90611.1 - 0.031 14.6 0.3 0.07 13.5 0.1 1.8 2 1 0 2 2 1 0 Penicillinase repressor DUF3822 PF12864.7 RLN90611.1 - 0.034 13.3 0.2 0.053 12.7 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3822) APG6_N PF17675.1 RLN90611.1 - 0.042 14.4 9.3 0.12 12.9 9.3 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region YlqD PF11068.8 RLN90611.1 - 0.086 13.2 1.0 0.66 10.3 2.3 1.7 2 0 0 2 2 2 0 YlqD protein DUF4600 PF15372.6 RLN90611.1 - 0.15 12.5 1.1 0.35 11.3 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) Osteopontin PF00865.18 RLN90611.1 - 0.19 11.2 14.5 0.33 10.4 14.5 1.3 1 0 0 1 1 1 0 Osteopontin ABC_tran_CTD PF16326.5 RLN90611.1 - 0.2 11.9 11.0 0.71 10.2 11.0 1.9 1 1 0 1 1 1 0 ABC transporter C-terminal domain DivIC PF04977.15 RLN90611.1 - 0.29 10.9 6.5 0.34 10.7 2.7 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 RLN90611.1 - 0.67 10.4 5.9 1.9 9.0 0.3 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) CCDC-167 PF15188.6 RLN90611.1 - 1.3 9.4 4.3 1 9.7 1.1 2.3 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 SlyX PF04102.12 RLN90611.1 - 1.6 9.4 4.0 20 5.9 0.8 2.5 1 1 1 2 2 2 0 SlyX DUF2894 PF11445.8 RLN90611.1 - 9 6.7 14.4 4.3 7.8 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) HECT PF00632.25 RLN90612.1 - 1.1e-92 310.9 0.0 2e-92 310.0 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Peptidase_C1 PF00112.23 RLN90613.1 - 0.00029 21.0 0.0 0.017 15.3 0.0 2.5 3 0 0 3 3 3 2 Papain family cysteine protease Peptidase_C1 PF00112.23 RLN90615.1 - 8.2e-05 22.8 0.0 0.035 14.2 0.0 2.4 2 0 0 2 2 2 2 Papain family cysteine protease WD40 PF00400.32 RLN90616.1 - 4.2e-11 43.2 3.6 0.0016 19.2 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat Ank_4 PF13637.6 RLN90617.1 - 8.7e-14 51.7 0.7 3.1e-08 34.0 0.0 2.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN90617.1 - 5.1e-12 46.2 0.1 1.6e-11 44.6 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN90617.1 - 3.9e-06 27.0 0.0 0.024 15.0 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN90617.1 - 7.3e-06 25.9 0.0 0.012 16.0 0.0 3.4 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 RLN90617.1 - 0.00019 21.7 0.5 0.049 14.1 0.0 3.2 2 1 0 2 2 2 1 Ankyrin repeat DUF745 PF05335.13 RLN90617.1 - 0.1 12.3 4.3 0.26 11.0 4.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF745) MukF_M PF17192.4 RLN90617.1 - 0.52 10.0 11.2 0.29 10.8 7.3 2.4 2 1 0 2 2 2 0 MukF middle domain Exonuc_VII_L PF02601.15 RLN90617.1 - 3.9 6.9 8.0 8.8 5.8 8.0 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pep_deformylase PF01327.21 RLN90618.1 - 1.2e-39 135.4 0.0 1.6e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase Phage_integrase PF00589.22 RLN90620.1 - 2.4e-05 24.2 0.0 8.3e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Phage integrase family Tub PF01167.18 RLN90621.1 - 7.7e-71 238.6 0.0 1e-70 238.3 0.0 1.1 1 0 0 1 1 1 1 Tub family zf-RING_2 PF13639.6 RLN90621.1 - 4e-09 36.6 4.3 4e-09 36.6 4.3 1.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 RLN90621.1 - 3e-05 24.2 4.4 8.6e-05 22.8 4.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain RINGv PF12906.7 RLN90621.1 - 0.00025 21.1 3.8 0.0005 20.1 3.8 1.5 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4_2 PF13923.6 RLN90621.1 - 0.00025 20.8 4.3 0.00076 19.3 4.3 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF3527 PF12043.8 RLN90621.1 - 0.00042 20.0 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3527) zf-ANAPC11 PF12861.7 RLN90621.1 - 0.013 15.5 1.8 0.05 13.6 1.8 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RLN90621.1 - 0.018 14.9 5.1 0.042 13.7 5.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN90621.1 - 0.039 13.9 3.0 0.093 12.7 3.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 RLN90621.1 - 0.94 9.3 5.8 0.34 10.7 1.3 2.5 2 1 0 2 2 2 0 RING-like zinc finger BET PF17035.5 RLN90622.1 - 0.21 11.8 8.2 3.6 7.8 1.3 3.9 3 0 0 3 3 3 0 Bromodomain extra-terminal - transcription regulation ACC_central PF08326.12 RLN90624.1 - 1.9e-70 238.0 5.2 2.3e-70 237.7 5.2 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.17 RLN90624.1 - 1.3e-46 158.8 0.0 4.3e-46 157.1 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 RLN90624.1 - 1.4e-23 83.0 0.0 4e-23 81.6 0.0 1.8 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 RLN90624.1 - 4.9e-09 35.9 0.0 1.7e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 RLN90624.1 - 0.00038 20.5 0.0 0.0011 19.1 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 RLN90624.1 - 0.00052 19.6 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 RLN90624.1 - 0.0017 17.9 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus DUF148 PF02520.17 RLN90624.1 - 0.008 16.3 0.2 0.055 13.6 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF148 Beach PF02138.18 RLN90624.1 - 0.011 15.1 0.1 0.019 14.4 0.1 1.3 1 0 0 1 1 1 0 Beige/BEACH domain TAF4 PF05236.14 RLN90625.1 - 0.0016 18.2 7.5 0.002 17.9 7.5 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Coiled-coil_56 PF09813.9 RLN90625.1 - 0.061 13.4 6.2 0.12 12.4 6.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 TERB2 PF15101.6 RLN90625.1 - 1.1 9.3 8.0 4.8 7.2 6.9 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 TFIIA PF03153.13 RLN90625.1 - 1.4 8.8 15.1 1.7 8.6 15.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spem1 PF15670.5 RLN90626.1 - 0.015 14.9 0.1 0.016 14.8 0.1 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 Pkinase PF00069.25 RLN90627.1 - 1.9e-32 112.7 0.0 5.6e-22 78.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90627.1 - 2.9e-15 56.2 0.0 7.3e-15 54.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN90627.1 - 8e-06 25.4 0.0 8.2e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like PRKCSH-like PF12999.7 RLN90628.1 - 3.5e-29 101.8 8.0 3.5e-29 101.8 8.0 2.9 3 1 0 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 RLN90628.1 - 4.1e-25 88.3 0.0 1.1e-24 86.9 0.0 1.7 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 RLN90628.1 - 0.0013 19.7 0.2 0.0081 17.1 0.0 2.5 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Phage_TAC_11 PF11836.8 RLN90628.1 - 0.015 15.4 0.4 0.015 15.4 0.4 2.3 2 0 0 2 2 2 0 Phage tail tube protein, GTA-gp10 CRA PF06589.11 RLN90628.1 - 1.6 8.9 4.0 4 7.5 4.0 1.6 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Ldl_recept_a PF00057.18 RLN90628.1 - 8.5 6.7 17.5 14 6.0 5.2 2.7 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A Yippee-Mis18 PF03226.14 RLN90629.1 - 2.9e-23 82.1 0.0 4.8e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Seryl_tRNA_N PF02403.22 RLN90629.1 - 0.061 13.6 0.2 0.061 13.6 0.2 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Apo-CII PF05355.11 RLN90629.1 - 0.12 12.6 0.1 0.32 11.2 0.0 1.7 2 0 0 2 2 2 0 Apolipoprotein C-II BROMI PF14961.6 RLN90629.1 - 0.5 7.7 4.7 0.65 7.3 0.2 2.0 2 0 0 2 2 2 0 Broad-minded protein Eapp_C PF10238.9 RLN90629.1 - 1.7 8.7 8.3 14 5.7 2.8 3.0 2 1 0 2 2 2 0 E2F-associated phosphoprotein DUF4611 PF15387.6 RLN90629.1 - 3 8.1 13.5 2.9 8.2 5.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Ribosomal_L17 PF01196.19 RLN90630.1 - 2.3e-32 111.7 0.6 2.9e-32 111.4 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 Pkinase PF00069.25 RLN90631.1 - 8.7e-78 261.3 0.0 1e-77 261.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90631.1 - 1e-31 110.2 0.0 1.3e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RLN90631.1 - 9.1e-06 24.9 0.0 1.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RLN90631.1 - 3.7e-05 23.2 0.1 0.00018 20.9 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 RLN90631.1 - 0.012 15.6 0.1 0.042 13.8 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 RLN90631.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 RLN90631.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WW PF00397.26 RLN90635.1 - 4.3e-34 116.3 29.1 1.6e-09 37.7 2.8 4.5 4 0 0 4 4 4 4 WW domain Glyco_hyd_101C PF17451.2 RLN90635.1 - 6.7e-06 26.4 9.6 0.42 10.9 0.1 4.5 4 0 0 4 4 4 4 Glycosyl hydrolase 101 beta sandwich domain CMAS PF02353.20 RLN90636.1 - 8.4e-27 94.2 0.0 1.5e-26 93.3 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 RLN90636.1 - 0.0012 19.4 0.0 0.0027 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN90636.1 - 0.0013 19.4 0.0 0.003 18.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN90636.1 - 0.0023 18.7 0.0 0.0045 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CENP-B_dimeris PF09026.10 RLN90637.1 - 0.3 11.5 5.1 0.86 10.0 5.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain AAA_13 PF13166.6 RLN90637.1 - 5.5 5.5 13.1 2.3 6.7 10.3 1.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 RLN90638.1 - 0.0039 17.7 0.1 0.0061 17.1 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 RLN90638.1 - 0.044 13.5 0.1 0.085 12.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN90638.1 - 0.056 13.0 0.1 0.085 12.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 RLN90638.1 - 0.23 12.0 0.2 0.53 10.8 0.1 1.6 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 RLN90639.1 - 2e-29 102.5 27.8 2e-29 102.5 27.8 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RLN90639.1 - 1.1e-23 84.3 0.5 1.7e-14 54.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 RLN90639.1 - 6.8e-07 28.9 0.9 0.0061 16.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN90639.1 - 1e-06 28.7 0.0 0.0037 17.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 RLN90639.1 - 1.1e-05 25.7 0.2 0.12 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RLN90639.1 - 3.7e-05 24.3 1.2 0.062 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 RLN90639.1 - 4.7e-05 23.0 0.5 0.29 10.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 RLN90639.1 - 8.7e-05 22.6 0.2 0.47 10.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 RLN90639.1 - 0.00046 20.7 1.2 0.79 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 RLN90639.1 - 0.00092 19.6 0.2 1.4 9.3 0.1 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 RLN90639.1 - 0.001 18.8 3.5 0.68 9.6 0.2 2.3 2 0 0 2 2 2 2 AAA domain PDR_assoc PF08370.11 RLN90639.1 - 0.0035 17.1 0.6 0.0035 17.1 0.6 2.3 2 0 0 2 2 2 1 Plant PDR ABC transporter associated TsaE PF02367.17 RLN90639.1 - 0.0039 17.2 1.3 0.27 11.2 0.2 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 RLN90639.1 - 0.0041 17.3 0.2 4.5 7.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 RLN90639.1 - 0.0098 16.1 0.6 0.61 10.3 0.2 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RLN90639.1 - 0.011 15.0 2.0 1.9 7.8 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin Ploopntkinase3 PF18751.1 RLN90639.1 - 0.014 15.3 0.8 2.7 7.9 0.1 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 RLN90639.1 - 0.024 14.4 0.5 7 6.3 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 RLN90639.1 - 0.026 14.9 2.1 1.3 9.4 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 RLN90639.1 - 0.027 14.1 2.2 2.6 7.6 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 RLN90639.1 - 0.034 13.1 1.0 4.4 6.2 0.2 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 RLN90639.1 - 0.049 14.0 0.5 9.9 6.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 RLN90639.1 - 0.059 13.3 3.2 2.8 7.9 0.7 2.4 2 0 0 2 2 2 0 NACHT domain ABC_trans_N PF14510.6 RLN90639.1 - 0.086 13.5 0.0 0.26 11.9 0.0 1.8 1 0 0 1 1 1 0 ABC-transporter N-terminal AAA_21 PF13304.6 RLN90639.1 - 0.095 12.5 0.9 4.8 6.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 RLN90639.1 - 0.12 12.5 6.3 2 8.5 0.8 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain NTPase_1 PF03266.15 RLN90639.1 - 0.12 12.3 1.1 4.5 7.1 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_17 PF13207.6 RLN90639.1 - 0.15 12.5 0.6 3.3 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 RLN90639.1 - 0.18 11.9 0.2 27 4.8 0.0 2.4 2 0 0 2 2 2 0 Dynamin family DnaB_C PF03796.15 RLN90639.1 - 0.25 10.6 0.7 9.8 5.4 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain T2SSE PF00437.20 RLN90639.1 - 0.25 10.3 0.3 2.4 7.1 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 RLN90639.1 - 0.26 11.6 3.5 3.7 7.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 RLN90639.1 - 0.39 10.5 1.6 0.74 9.6 0.4 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC2_membrane_3 PF12698.7 RLN90639.1 - 6.3 5.8 24.1 16 4.5 24.1 1.7 1 0 0 1 1 1 0 ABC-2 family transporter protein SCP-1 PF05483.12 RLN90640.1 - 0.17 9.9 0.2 0.22 9.5 0.2 1.1 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) zf-CCHC PF00098.23 RLN90641.1 - 7.8e-08 32.1 2.9 7.8e-08 32.1 2.9 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 RLN90641.1 - 0.02 14.7 1.2 0.02 14.7 1.2 2.1 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 RLN90641.1 - 0.13 12.1 0.5 0.13 12.1 0.5 2.6 2 1 0 2 2 2 0 Zinc knuckle eIF3g PF12353.8 RLN90641.1 - 0.8 10.1 7.9 0.69 10.3 0.3 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Arm PF00514.23 RLN90642.1 - 1.6e-18 66.1 6.1 0.0029 17.6 0.0 5.9 5 1 0 5 5 5 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN90642.1 - 7.1e-09 36.0 12.8 0.0042 17.6 0.1 5.2 3 2 2 5 5 5 4 HEAT-like repeat HEAT PF02985.22 RLN90642.1 - 1.2e-08 34.5 5.3 7 7.2 0.1 6.2 6 0 0 6 6 6 4 HEAT repeat T3SS_ExsE PF18286.1 RLN90642.1 - 0.0017 18.3 4.8 24 4.9 0.0 5.2 6 0 0 6 6 6 1 Type III secretion system ExsE Atx10homo_assoc PF09759.9 RLN90642.1 - 0.005 16.8 0.1 8.2 6.5 0.1 3.7 1 1 3 4 4 4 1 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 RLN90642.1 - 0.031 14.9 21.6 4.8 8.1 1.0 5.9 5 1 1 6 6 6 0 PBS lyase HEAT-like repeat Antimicrobial17 PF08129.11 RLN90642.1 - 5.7 7.0 8.6 55 3.8 0.1 4.8 6 0 0 6 6 6 0 Alpha/beta enterocin family UVR PF02151.19 RLN90644.1 - 1.4e-08 34.2 18.4 6.8e-05 22.5 1.7 2.9 3 0 0 3 3 3 2 UvrB/uvrC motif zf-Di19 PF05605.12 RLN90644.1 - 0.0014 18.8 13.3 0.98 9.8 7.0 3.3 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding FlxA PF14282.6 RLN90644.1 - 0.079 13.0 2.2 0.21 11.6 2.2 1.7 1 0 0 1 1 1 0 FlxA-like protein zf_UBZ PF18439.1 RLN90644.1 - 0.13 11.8 8.2 0.55 9.9 0.1 3.6 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger PRP21_like_P PF12230.8 RLN90644.1 - 0.2 11.5 2.3 6.9 6.5 0.4 3.0 1 1 1 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein zf-C2H2_4 PF13894.6 RLN90644.1 - 0.41 11.6 7.2 69 4.7 0.1 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger TF_Zn_Ribbon PF08271.12 RLN90644.1 - 6 6.5 14.2 0.21 11.1 0.3 3.6 4 0 0 4 4 4 0 TFIIB zinc-binding Terminase_GpA PF05876.12 RLN90644.1 - 6 5.3 7.3 11 4.5 7.3 1.3 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DUF4140 PF13600.6 RLN90644.1 - 7.4 7.1 9.5 0.31 11.5 2.1 2.4 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) bZIP_2 PF07716.15 RLN90645.1 - 0.017 15.2 8.6 0.038 14.1 8.6 1.5 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 RLN90645.1 - 3.4 7.8 14.4 0.34 11.1 8.5 2.1 1 1 1 2 2 2 0 bZIP transcription factor Sugar_tr PF00083.24 RLN90646.1 - 3.7e-42 144.7 26.9 6.5e-40 137.3 26.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN90646.1 - 1.4e-33 116.3 44.7 2.2e-28 99.2 21.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FYVE_2 PF02318.16 RLN90647.1 - 0.35 11.1 4.0 0.71 10.1 4.0 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger PHD_4 PF16866.5 RLN90648.1 - 0.11 12.6 1.3 0.28 11.3 1.3 1.8 1 1 0 1 1 1 0 PHD-finger FYVE PF01363.21 RLN90648.1 - 7.5 6.8 8.7 0.42 10.8 3.1 1.9 2 0 0 2 2 2 0 FYVE zinc finger Palm_thioest PF02089.15 RLN90649.1 - 4.4e-51 174.1 0.0 5.3e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 RLN90649.1 - 1.1e-05 25.2 0.1 2.4e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 RLN90649.1 - 0.00014 21.5 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 RLN90649.1 - 0.00021 22.0 0.0 0.00031 21.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 RLN90649.1 - 0.00085 18.9 0.1 0.0021 17.6 0.1 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 RLN90649.1 - 0.00099 18.9 0.8 0.0039 16.9 0.0 2.1 3 0 0 3 3 3 1 PGAP1-like protein DUF3089 PF11288.8 RLN90649.1 - 0.021 14.4 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Lipase_2 PF01674.18 RLN90649.1 - 0.081 12.4 0.2 0.83 9.1 0.3 2.3 1 1 0 1 1 1 0 Lipase (class 2) FSH1 PF03959.13 RLN90649.1 - 0.083 12.5 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) RCDG1 PF15725.5 RLN90649.1 - 0.13 12.6 1.3 13 6.3 1.2 2.3 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein DUF2974 PF11187.8 RLN90649.1 - 0.14 11.6 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF915 PF06028.11 RLN90649.1 - 0.17 11.2 0.1 1 8.6 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) FYVE_2 PF02318.16 RLN90650.1 - 0.052 13.8 6.3 0.15 12.2 6.3 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 RLN90651.1 - 0.41 10.8 11.4 1 9.6 11.4 1.7 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN90651.1 - 3.4 7.9 8.2 8.3 6.7 8.2 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger MFS_1 PF07690.16 RLN90652.1 - 8e-38 130.3 37.4 3.9e-33 114.9 22.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN90652.1 - 1e-05 24.6 5.6 0.0014 17.6 2.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 RLN90652.1 - 0.12 11.2 10.2 0.94 8.3 0.1 2.5 2 0 0 2 2 2 0 MFS_1 like family DUF1456 PF07308.13 RLN90654.1 - 0.0054 17.0 0.1 0.038 14.3 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1456) FYVE_2 PF02318.16 RLN90654.1 - 0.016 15.4 6.7 0.016 15.4 6.7 2.4 3 0 0 3 3 3 0 FYVE-type zinc finger FYVE PF01363.21 RLN90654.1 - 0.028 14.6 7.5 0.068 13.3 7.5 1.7 1 0 0 1 1 1 0 FYVE zinc finger DEAD PF00270.29 RLN90655.1 - 1.5e-15 57.4 0.0 2.8e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 RLN90655.1 - 9.4e-07 29.5 0.5 3e-06 27.9 0.5 1.8 1 0 0 1 1 1 1 RecQ zinc-binding Helicase_C PF00271.31 RLN90655.1 - 0.00038 20.8 0.0 0.00096 19.5 0.0 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Flavodoxin_5 PF12724.7 RLN90655.1 - 0.05 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain SNF2_N PF00176.23 RLN90655.1 - 0.15 10.7 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF4350 PF14258.6 RLN90655.1 - 0.17 12.3 0.5 2.3 8.7 0.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4350) FYVE PF01363.21 RLN90656.1 - 0.28 11.4 8.3 0.56 10.4 8.3 1.5 1 0 0 1 1 1 0 FYVE zinc finger OrfB_Zn_ribbon PF07282.11 RLN90656.1 - 0.62 10.0 6.0 2.4 8.1 6.0 2.0 1 1 0 1 1 1 0 Putative transposase DNA-binding domain PHD_4 PF16866.5 RLN90656.1 - 1.9 8.6 8.2 4.6 7.4 8.2 1.7 1 1 0 1 1 1 0 PHD-finger FYVE_2 PF02318.16 RLN90657.1 - 0.031 14.5 10.8 0.077 13.2 10.8 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 RLN90657.1 - 8.2 6.7 11.6 23 5.2 11.6 1.8 1 0 0 1 1 1 0 FYVE zinc finger FYVE PF01363.21 RLN90658.1 - 0.49 10.6 6.3 1.2 9.3 6.3 1.6 1 0 0 1 1 1 0 FYVE zinc finger FYVE PF01363.21 RLN90659.1 - 0.0037 17.4 5.8 0.0082 16.3 5.8 1.5 1 0 0 1 1 1 1 FYVE zinc finger PHD PF00628.29 RLN90659.1 - 0.019 14.8 6.2 0.036 14.0 6.2 1.5 1 0 0 1 1 1 0 PHD-finger Prim_Zn_Ribbon PF08273.12 RLN90659.1 - 0.16 12.3 4.1 0.34 11.2 4.1 1.5 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase zf-B_box PF00643.24 RLN90659.1 - 4.3 7.6 8.8 1 9.6 4.9 2.0 2 0 0 2 2 2 0 B-box zinc finger Ribosomal_L32p PF01783.23 RLN90659.1 - 5.7 7.3 6.8 23 5.3 6.8 2.1 1 1 0 1 1 1 0 Ribosomal L32p protein family AA_permease_2 PF13520.6 RLN90660.1 - 2.1e-27 96.0 21.2 2.8e-27 95.6 21.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN90660.1 - 3.9e-22 78.5 13.9 3.9e-22 78.5 13.9 1.3 2 0 0 2 2 2 1 Amino acid permease DUF2568 PF10823.8 RLN90660.1 - 0.036 14.3 1.2 0.036 14.3 1.2 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF2568) AA_permease_2 PF13520.6 RLN90661.1 - 3.7e-23 82.0 24.8 4.9e-23 81.6 24.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN90661.1 - 8.3e-14 51.0 20.7 1.5e-13 50.2 20.7 1.3 1 0 0 1 1 1 1 Amino acid permease Exonuc_VII_L PF02601.15 RLN90661.1 - 0.12 11.9 2.7 0.17 11.4 2.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit GLE1 PF07817.13 RLN90661.1 - 0.2 10.9 0.1 5 6.3 0.0 2.3 2 0 0 2 2 2 0 GLE1-like protein bZIP_2 PF07716.15 RLN90661.1 - 7.1 6.8 18.1 0.1 12.7 9.9 2.0 1 1 1 2 2 2 0 Basic region leucine zipper Peroxin-3 PF04882.12 RLN90662.1 - 5.6e-12 45.4 1.9 1.7e-06 27.3 0.1 3.3 1 1 1 2 2 2 2 Peroxin-3 WD-3 PF09765.9 RLN90662.1 - 0.035 13.4 0.6 0.065 12.5 0.1 1.6 2 0 0 2 2 2 0 WD-repeat region Nudc_N PF14050.6 RLN90663.1 - 4.8e-19 68.1 0.3 9.8e-19 67.1 0.0 1.6 2 0 0 2 2 2 1 N-terminal conserved domain of Nudc. CS PF04969.16 RLN90663.1 - 1.9e-07 32.0 0.0 2.9e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 CS domain SecA_SW PF07516.13 RLN90663.1 - 0.043 13.9 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 SecA Wing and Scaffold domain EMG1 PF03587.14 RLN90664.1 - 0.00042 20.0 0.0 0.0014 18.3 0.0 1.7 2 0 0 2 2 2 1 EMG1/NEP1 methyltransferase Capsid_NCLDV PF04451.12 RLN90664.1 - 0.012 15.4 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein Perm-CXXC PF15629.6 RLN90665.1 - 4.2 7.7 8.8 3.7 7.9 2.3 2.6 2 0 0 2 2 2 0 Permuted single zf-CXXC unit BRO1 PF03097.18 RLN90666.1 - 2.8e-97 326.0 0.0 2.8e-97 326.0 0.0 2.1 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 RLN90666.1 - 2.4e-62 210.9 12.4 2.4e-62 210.9 12.4 2.1 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV FbpA PF05833.11 RLN90666.1 - 0.067 11.9 9.4 0.73 8.5 9.4 2.5 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) MnmE_helical PF12631.7 RLN90666.1 - 9 6.4 12.1 48 4.0 11.8 2.5 1 1 0 1 1 1 0 MnmE helical domain DOT1 PF08123.13 RLN90667.1 - 5.2e-25 88.2 0.0 8.6e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 RLN90667.1 - 6.7e-07 28.9 0.0 1.6e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 RLN90667.1 - 1.4e-05 25.7 0.0 4.5e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN90667.1 - 0.00098 18.9 0.0 0.0022 17.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN90667.1 - 0.0011 19.5 0.0 0.037 14.7 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN90667.1 - 0.005 17.5 0.0 0.014 16.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 RLN90667.1 - 0.022 14.5 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 RLN90667.1 - 0.029 14.2 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 RLN90667.1 - 0.083 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 RLN90667.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain G6PD_C PF02781.16 RLN90668.1 - 4e-109 364.3 0.0 5.1e-109 364.0 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 RLN90668.1 - 3.1e-56 190.8 0.0 4.6e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Phosphodiest PF01663.22 RLN90669.1 - 5.3e-15 55.9 0.5 9.3e-11 41.9 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RLN90669.1 - 0.0012 18.3 0.0 0.01 15.2 0.0 2.1 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 RLN90669.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Metalloenzyme superfamily eIF-5a PF01287.20 RLN90670.1 - 1.2e-24 86.2 0.0 1.6e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 RLN90670.1 - 3.5e-05 23.7 0.1 5.1e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain KH_1 PF00013.29 RLN90671.1 - 1.4e-09 37.7 0.1 3e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 KH domain ZFYVE21_C PF16696.5 RLN90671.1 - 0.037 13.9 0.1 0.069 13.0 0.1 1.5 1 0 0 1 1 1 0 Zinc finger FYVE domain-containing protein 21 C-terminus PhoD PF09423.10 RLN90672.1 - 4.8e-08 32.4 0.0 1.2e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 PhoD-like phosphatase WW PF00397.26 RLN90673.1 - 6.3e-05 23.0 0.3 0.00013 22.0 0.3 1.5 1 0 0 1 1 1 1 WW domain FOXP-CC PF16159.5 RLN90673.1 - 0.013 16.1 2.8 0.065 13.9 2.8 2.2 1 0 0 1 1 1 0 FOXP coiled-coil domain OrsD PF12013.8 RLN90673.1 - 0.016 15.6 7.1 0.8 10.2 3.5 3.2 2 1 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D IQ PF00612.27 RLN90673.1 - 0.064 13.1 5.4 1.4 8.9 0.4 2.9 2 0 0 2 2 2 0 IQ calmodulin-binding motif Rep_trans PF02486.19 RLN90673.1 - 0.31 10.7 4.1 0.1 12.3 0.8 1.9 2 1 0 2 2 2 0 Replication initiation factor LigB PF02900.18 RLN90674.1 - 8.6e-32 110.3 0.0 1e-31 110.1 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase USP8_dimer PF08969.11 RLN90675.1 - 1.9e-06 28.0 0.0 2.3e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 USP8 dimerisation domain CIAPIN1 PF05093.13 RLN90676.1 - 7.7e-17 61.7 20.1 9.8e-13 48.5 3.8 2.8 2 1 1 3 3 3 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DMRL_synthase PF00885.19 RLN90676.1 - 0.046 13.6 0.2 0.082 12.7 0.2 1.4 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase Cucumo_coat PF00760.18 RLN90676.1 - 0.053 13.2 0.1 0.084 12.5 0.1 1.2 1 0 0 1 1 1 0 Cucumovirus coat protein ATPgrasp_N PF18130.1 RLN90676.1 - 0.066 13.8 0.5 0.44 11.2 0.2 2.5 2 1 0 2 2 2 0 ATP-grasp N-terminal domain DDR_swiveling PF18427.1 RLN90677.1 - 0.069 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 DD-reactivating factor swiveling domain SKIP_SNW PF02731.15 RLN90678.1 - 9.1e-72 240.0 3.0 9.1e-72 240.0 3.0 2.3 2 0 0 2 2 2 1 SKIP/SNW domain SPATIAL PF15256.6 RLN90678.1 - 0.47 10.8 6.6 1.3 9.3 6.6 1.7 1 0 0 1 1 1 0 SPATIAL Cwf_Cwc_15 PF04889.12 RLN90678.1 - 2.1 8.0 34.2 0.16 11.7 28.3 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein HTH_Tnp_Tc5 PF03221.16 RLN90681.1 - 1.3e-06 28.3 0.0 7.4e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 RLN90681.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain PAP1 PF08601.10 RLN90682.1 - 0.039 13.7 11.2 0.049 13.3 11.2 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 SOG2 PF10428.9 RLN90682.1 - 0.075 12.2 7.4 0.091 11.9 7.4 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Med8 PF10232.9 RLN90682.1 - 0.16 11.6 3.4 0.29 10.7 3.3 1.6 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 TFIIF_alpha PF05793.12 RLN90682.1 - 0.25 9.9 14.7 0.39 9.3 14.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Macoilin PF09726.9 RLN90682.1 - 0.88 8.1 5.8 0.98 7.9 5.8 1.0 1 0 0 1 1 1 0 Macoilin family Nop14 PF04147.12 RLN90682.1 - 0.99 7.5 8.2 1.2 7.3 8.2 1.1 1 0 0 1 1 1 0 Nop14-like family PI3K_1B_p101 PF10486.9 RLN90682.1 - 2.3 5.9 4.9 2.8 5.6 4.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Menin PF05053.13 RLN90682.1 - 4.4 5.5 6.7 4.9 5.4 6.7 1.1 1 0 0 1 1 1 0 Menin Rrn6 PF10214.9 RLN90682.1 - 9 4.6 8.8 11 4.4 8.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PC4 PF02229.16 RLN90683.1 - 1.7e-39 133.2 0.3 8.4e-20 70.2 0.0 2.3 2 0 0 2 2 2 2 Transcriptional Coactivator p15 (PC4) HTH_33 PF13592.6 RLN90683.1 - 0.4 10.3 4.4 0.99 9.1 4.4 1.7 1 0 0 1 1 1 0 Winged helix-turn helix SRF-TF PF00319.18 RLN90684.1 - 1.2e-24 85.5 1.3 1.5e-24 85.2 0.2 1.7 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Abhydrolase_6 PF12697.7 RLN90685.1 - 5e-14 53.4 3.6 6e-14 53.2 3.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN90685.1 - 1.3e-07 31.1 0.0 7.2e-05 22.2 0.0 2.4 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN90685.1 - 0.034 13.8 0.0 0.54 9.9 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold GatB_N PF02934.15 RLN90686.1 - 4.2e-101 337.9 0.0 1.1e-100 336.6 0.0 1.6 1 1 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 RLN90686.1 - 3.3e-38 130.9 0.0 6.9e-38 129.9 0.0 1.6 1 0 0 1 1 1 1 GatB domain Abhydrolase_6 PF12697.7 RLN90687.1 - 1.7e-17 64.8 0.0 6.9e-11 43.2 0.0 2.9 2 1 0 3 3 3 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN90687.1 - 0.0011 18.2 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN90688.1 - 1.9e-11 45.0 2.8 2.6e-11 44.5 2.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN90688.1 - 6.3e-06 25.6 0.1 1.3e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN90688.1 - 0.025 14.2 0.0 0.089 12.4 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN90689.1 - 2.6e-14 54.3 1.8 3.2e-14 54.1 1.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN90689.1 - 0.0002 20.7 0.0 0.00039 19.8 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN90689.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN90690.1 - 2.4e-12 48.0 0.7 2.9e-12 47.7 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN90690.1 - 8.5e-06 25.2 0.0 0.00019 20.7 0.0 2.4 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN90690.1 - 0.031 13.9 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN90691.1 - 2e-11 44.9 0.6 3.5e-11 44.1 0.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN90691.1 - 2.1e-05 23.9 0.0 4.8e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN90691.1 - 0.013 15.1 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN90692.1 - 8.3e-13 49.5 0.8 1e-12 49.1 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN90692.1 - 7.4e-05 22.1 0.0 0.00015 21.1 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN90692.1 - 0.011 15.4 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pkinase PF00069.25 RLN90693.1 - 2.2e-09 37.1 0.0 1.2e-08 34.7 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90693.1 - 4.6e-08 32.7 0.0 2e-06 27.3 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pec_lyase_C PF00544.19 RLN90694.1 - 0.029 13.9 0.1 0.042 13.4 0.1 1.2 1 0 0 1 1 1 0 Pectate lyase Arm PF00514.23 RLN90695.1 - 4.8e-22 77.2 15.9 3.2e-05 23.8 0.0 8.5 10 0 0 10 10 10 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN90695.1 - 9.2e-07 28.6 2.6 1.8 9.0 0.0 6.2 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 RLN90695.1 - 2.9e-06 27.7 14.4 0.0029 18.1 0.3 5.6 5 1 3 8 8 8 4 HEAT-like repeat HEAT_2 PF13646.6 RLN90695.1 - 0.0012 19.1 14.0 0.043 14.2 1.9 3.6 2 1 0 3 3 3 2 HEAT repeats HEAT_PBS PF03130.16 RLN90695.1 - 0.15 12.8 11.2 40 5.3 0.2 5.6 5 1 1 6 6 6 0 PBS lyase HEAT-like repeat Nup54_C PF18437.1 RLN90695.1 - 0.34 10.8 3.2 1.9 8.4 0.5 3.7 4 0 0 4 4 4 0 Nup54 C-terminal interacting domain Pox_MCEL PF03291.16 RLN90698.1 - 8.8e-48 163.1 0.0 2.2e-47 161.8 0.0 1.7 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 RLN90698.1 - 4.3e-10 40.2 0.2 7.9e-08 32.9 0.2 2.6 1 1 0 1 1 1 1 Methyltransferase domain WW PF00397.26 RLN90698.1 - 6e-10 39.0 1.1 0.001 19.1 0.1 2.6 2 0 0 2 2 2 2 WW domain Methyltransf_12 PF08242.12 RLN90698.1 - 1.1e-07 32.5 0.0 3.2e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN90698.1 - 2e-07 31.0 0.0 4e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN90698.1 - 5.3e-07 29.6 0.0 4.2e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN90698.1 - 9.5e-07 29.4 0.1 4.2e-05 24.1 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 RLN90698.1 - 0.0095 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.20 RLN90698.1 - 0.014 14.7 0.2 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 RLN90698.1 - 0.15 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MetW PF07021.12 RLN90698.1 - 0.15 11.6 0.1 0.26 10.9 0.1 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF3730 PF12530.8 RLN90699.1 - 1e-15 57.9 2.0 1e-15 57.9 2.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3730) Cas9_Topo PF17894.1 RLN90699.1 - 0.02 14.9 0.0 2.4 8.3 0.0 2.8 2 0 0 2 2 2 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 Sulfotransfer_4 PF17784.1 RLN90699.1 - 0.025 14.4 0.7 0.052 13.4 0.1 1.9 2 0 0 2 2 2 0 Sulfotransferase domain HEAT_EZ PF13513.6 RLN90699.1 - 0.052 14.1 0.5 0.052 14.1 0.5 4.7 4 1 0 4 4 4 0 HEAT-like repeat HEAT PF02985.22 RLN90699.1 - 0.46 10.9 12.1 0.31 11.4 0.3 4.6 5 0 0 5 5 5 0 HEAT repeat Mg_trans_NIPA PF05653.14 RLN90700.1 - 1.3e-20 73.7 1.1 1.7e-20 73.4 1.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA UbiA PF01040.18 RLN90700.1 - 9.5e-05 21.8 1.3 0.00013 21.4 1.3 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3098 PF11297.8 RLN90700.1 - 0.048 13.3 0.1 0.12 12.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) DREPP PF05558.12 RLN90700.1 - 0.24 11.3 5.9 0.38 10.6 5.9 1.2 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide EamA PF00892.20 RLN90700.1 - 0.7 10.1 11.4 0.29 11.3 8.1 2.1 2 1 0 2 2 2 0 EamA-like transporter family peroxidase PF00141.23 RLN90701.1 - 1.9e-47 161.9 0.0 3.6e-47 161.0 0.0 1.5 1 0 0 1 1 1 1 Peroxidase Ncstrn_small PF18266.1 RLN90701.1 - 8.4e-20 71.4 0.0 1.9e-19 70.3 0.0 1.6 2 0 0 2 2 2 1 Nicastrin small lobe Nicastrin PF05450.15 RLN90701.1 - 4.4e-05 23.1 0.2 4.4e-05 23.1 0.2 1.6 2 0 0 2 2 2 1 Nicastrin Peptidase_M28 PF04389.17 RLN90701.1 - 0.019 14.7 0.8 0.032 13.9 0.8 1.4 1 0 0 1 1 1 0 Peptidase family M28 Tubulin PF00091.25 RLN90702.1 - 2e-58 197.8 0.0 3.8e-58 196.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RLN90702.1 - 8.7e-49 164.9 0.0 2.4e-48 163.4 0.0 1.7 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 RLN90702.1 - 0.0031 16.8 0.0 0.007 15.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin like TRAPP PF04051.16 RLN90703.1 - 1.2e-30 106.1 0.0 1.4e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Kelch_1 PF01344.25 RLN90704.1 - 2.2e-12 46.3 2.4 0.039 13.5 0.0 7.0 7 0 0 7 7 7 3 Kelch motif Kelch_5 PF13854.6 RLN90704.1 - 5.9e-09 35.7 0.5 0.4 10.7 0.0 5.8 7 0 0 7 7 7 3 Kelch motif Kelch_4 PF13418.6 RLN90704.1 - 1.7e-05 24.7 2.9 0.55 10.3 0.0 5.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 RLN90704.1 - 2.7e-05 24.3 9.4 0.2 12.0 0.0 6.4 8 0 0 8 8 8 2 Kelch motif Kelch_2 PF07646.15 RLN90704.1 - 7.8e-05 22.5 8.5 1.4 9.0 0.0 6.6 7 0 0 7 7 7 2 Kelch motif EB PF01683.18 RLN90704.1 - 0.036 14.4 2.7 0.073 13.4 2.7 1.4 1 0 0 1 1 1 0 EB module Macoilin PF09726.9 RLN90704.1 - 2 6.9 17.9 2.6 6.5 17.9 1.1 1 0 0 1 1 1 0 Macoilin family ING PF12998.7 RLN90705.1 - 1.4e-16 60.9 2.7 2.6e-16 60.0 2.7 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 RLN90705.1 - 4.7e-05 23.2 8.0 8.2e-05 22.4 8.0 1.4 1 0 0 1 1 1 1 PHD-finger NdhM PF10664.9 RLN90705.1 - 0.018 15.3 0.1 0.031 14.5 0.1 1.3 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M PHD_2 PF13831.6 RLN90705.1 - 0.08 12.5 2.8 0.22 11.1 2.8 1.8 1 0 0 1 1 1 0 PHD-finger GCN5L1 PF06320.13 RLN90705.1 - 0.16 12.2 2.9 0.17 12.0 1.8 1.7 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) Sds3 PF08598.11 RLN90706.1 - 1.8e-05 24.8 2.8 2.8e-05 24.2 2.8 1.3 1 0 0 1 1 1 1 Sds3-like PIG-L PF02585.17 RLN90707.1 - 1.5e-22 80.6 0.4 2.4e-22 79.9 0.4 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase MinC_N PF05209.13 RLN90708.1 - 0.056 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain Ferrochelatase PF00762.19 RLN90709.1 - 1.1e-94 317.1 0.0 1.2e-94 316.9 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 RLN90709.1 - 0.0047 17.2 0.0 5.1 7.5 0.0 3.2 3 0 0 3 3 3 1 CbiX Ank_2 PF12796.7 RLN90710.1 - 4.1e-49 165.1 16.6 4.2e-09 36.9 0.3 6.8 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN90710.1 - 2e-38 126.0 23.8 0.0096 16.4 0.0 12.9 12 1 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.6 RLN90710.1 - 4e-38 129.3 28.1 9.6e-08 32.4 0.4 8.8 5 3 3 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 RLN90710.1 - 3.7e-36 122.0 43.2 0.00019 21.7 2.6 11.7 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.6 RLN90710.1 - 4.2e-28 97.0 29.8 3.9e-07 30.2 0.2 11.4 4 2 7 12 12 12 10 Ankyrin repeats (many copies) Glucan_synthase PF02364.15 RLN90711.1 - 5.1e-149 498.0 1.6 1.4e-127 427.0 0.2 2.1 1 1 1 2 2 2 2 1,3-beta-glucan synthase component IQ PF00612.27 RLN90712.1 - 3.7e-12 44.9 76.9 0.024 14.4 6.4 11.5 11 0 0 11 11 11 9 IQ calmodulin-binding motif LRR_4 PF12799.7 RLN90712.1 - 0.00015 22.1 2.7 0.3 11.6 0.1 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RLN90712.1 - 0.9 9.8 3.7 4.7 7.5 0.2 3.1 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 RLN90712.1 - 0.94 10.3 4.3 9.7 7.2 0.3 3.3 3 1 0 3 3 3 0 Leucine Rich Repeat PTR2 PF00854.21 RLN90713.1 - 1.5e-56 191.9 8.9 2.1e-56 191.5 7.0 2.0 1 1 0 1 1 1 1 POT family WW PF00397.26 RLN90714.1 - 6e-26 90.2 28.2 5e-07 29.7 3.2 5.4 5 0 0 5 5 5 5 WW domain OCRE PF17780.1 RLN90714.1 - 0.0036 17.3 20.4 0.0074 16.3 0.1 4.5 4 2 1 5 5 5 3 OCRE domain MMADHC PF10229.9 RLN90714.1 - 0.13 12.0 1.8 1.6 8.4 0.0 2.8 2 1 1 3 3 3 0 Methylmalonic aciduria and homocystinuria type D protein YL1_C PF08265.11 RLN90714.1 - 0.67 9.8 11.8 5.7 6.8 0.7 3.7 3 0 0 3 3 3 0 YL1 nuclear protein C-terminal domain BT1 PF03092.16 RLN90715.1 - 5.8e-13 47.9 14.7 7.6e-12 44.2 0.7 3.2 2 1 1 3 3 3 3 BT1 family WBS_methylT PF12589.8 RLN90716.1 - 8.5e-10 39.3 13.2 4.2e-07 30.6 5.9 2.7 2 1 1 3 3 3 2 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 RLN90716.1 - 0.00095 19.8 0.0 0.0025 18.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN90716.1 - 0.013 16.2 0.1 0.051 14.3 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain Bactofilin PF04519.13 RLN90717.1 - 4.2e-19 68.7 2.6 5.5e-19 68.3 2.6 1.1 1 0 0 1 1 1 1 Polymer-forming cytoskeletal Pkinase PF00069.25 RLN90718.1 - 2e-72 243.8 0.0 2.2e-72 243.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90718.1 - 1.2e-29 103.4 0.0 1.6e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN90718.1 - 1.6e-06 27.7 0.0 0.00061 19.2 0.0 2.1 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 RLN90718.1 - 0.046 13.6 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN90718.1 - 0.063 12.2 0.0 0.12 11.3 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain TPR_1 PF00515.28 RLN90720.1 - 3.1e-08 33.1 3.2 0.0029 17.4 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat C2 PF00168.30 RLN90720.1 - 6.4e-05 23.2 0.0 0.00014 22.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain TPR_2 PF07719.17 RLN90720.1 - 7.7e-05 22.5 5.0 0.0046 17.0 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN90720.1 - 0.008 16.4 0.3 7 7.0 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 RLN90720.1 - 0.011 16.0 0.3 0.36 11.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Nup_retrotrp_bd PF10599.9 RLN90720.1 - 0.094 13.4 0.2 0.094 13.4 0.2 2.5 3 0 0 3 3 3 0 Retro-transposon transporting motif MIT PF04212.18 RLN90720.1 - 0.13 12.3 1.4 2.5 8.2 0.1 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 RLN90720.1 - 0.18 12.1 0.4 2.2 8.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DEAD PF00270.29 RLN90721.1 - 3.8e-06 26.8 0.4 0.014 15.2 0.1 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN90721.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.8 1 1 0 1 1 1 0 Helicase conserved C-terminal domain CBS PF00571.28 RLN90721.1 - 0.057 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 CBS domain Fer4_9 PF13187.6 RLN90722.1 - 0.046 13.9 9.8 0.11 12.6 9.8 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Rad50_zn_hook PF04423.14 RLN90722.1 - 0.067 13.0 1.4 2.8 7.9 0.6 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif HMW1C_N PF18071.1 RLN90722.1 - 0.16 11.8 0.1 0.31 10.8 0.1 1.4 1 0 0 1 1 1 0 HMW1C N-terminal FYVE PF01363.21 RLN90722.1 - 0.2 11.8 8.7 0.52 10.5 8.7 1.8 1 0 0 1 1 1 0 FYVE zinc finger DUF4628 PF15429.6 RLN90722.1 - 0.38 10.4 2.5 0.66 9.6 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) Form_Nir_trans PF01226.17 RLN90722.1 - 0.47 9.7 0.9 0.75 9.1 0.9 1.2 1 0 0 1 1 1 0 Formate/nitrite transporter GAF PF01590.26 RLN90723.1 - 1.6e-06 28.8 3.1 3.8e-06 27.6 0.7 2.7 3 0 0 3 3 3 1 GAF domain GAF_2 PF13185.6 RLN90723.1 - 0.0063 16.8 0.0 0.02 15.2 0.0 1.9 1 0 0 1 1 1 1 GAF domain Fer4_7 PF12838.7 RLN90723.1 - 0.029 15.0 0.9 0.029 15.0 0.9 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain Rad50_zn_hook PF04423.14 RLN90723.1 - 0.27 11.1 2.4 2.9 7.8 0.4 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif FYVE PF01363.21 RLN90723.1 - 0.33 11.1 12.4 0.99 9.6 12.4 1.8 1 0 0 1 1 1 0 FYVE zinc finger Secretin_N_2 PF07655.13 RLN90723.1 - 4 8.0 10.2 3.1 8.4 3.4 2.7 2 0 0 2 2 2 0 Secretin N-terminal domain Fer4_9 PF13187.6 RLN90724.1 - 0.057 13.6 9.8 0.14 12.3 9.8 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Rad50_zn_hook PF04423.14 RLN90724.1 - 0.12 12.3 1.4 3.4 7.6 0.6 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif FYVE PF01363.21 RLN90724.1 - 0.25 11.5 8.7 0.68 10.1 8.7 1.8 1 0 0 1 1 1 0 FYVE zinc finger DUF4628 PF15429.6 RLN90724.1 - 0.41 10.3 2.5 0.85 9.2 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) FYVE PF01363.21 RLN90725.1 - 0.21 11.8 8.5 0.54 10.4 8.5 1.7 1 0 0 1 1 1 0 FYVE zinc finger Form_Nir_trans PF01226.17 RLN90725.1 - 0.26 10.6 0.9 0.43 9.9 0.9 1.2 1 0 0 1 1 1 0 Formate/nitrite transporter Rad50_zn_hook PF04423.14 RLN90725.1 - 0.27 11.1 1.9 4.7 7.1 0.6 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif Fer4_9 PF13187.6 RLN90725.1 - 1.2 9.3 10.8 3.6 7.8 10.8 1.9 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4 PF00037.27 RLN90725.1 - 5.2 7.1 9.4 1.2 9.1 4.7 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain DUF4407 PF14362.6 RLN90726.1 - 0.11 11.9 3.8 0.2 11.0 3.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) P53 PF00870.18 RLN90726.1 - 0.17 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 P53 DNA-binding domain ALIX_LYPXL_bnd PF13949.6 RLN90726.1 - 0.22 10.8 5.2 0.51 9.6 5.3 1.5 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV HemX PF04375.14 RLN90726.1 - 0.28 10.4 0.1 0.28 10.4 0.1 2.6 3 0 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF848 PF05852.11 RLN90726.1 - 0.46 10.6 3.4 17 5.5 0.0 2.6 3 0 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) MerR-DNA-bind PF09278.11 RLN90726.1 - 2.3 8.8 11.2 4 8.0 0.0 4.4 4 1 0 4 4 4 0 MerR, DNA binding TT_ORF2 PF02957.15 RLN90726.1 - 3.4 8.6 7.9 4.6 8.2 0.1 3.3 3 0 0 3 3 3 0 TT viral ORF2 LPP PF04728.13 RLN90726.1 - 4.3 7.8 4.9 9.3 6.7 0.3 3.1 3 0 0 3 3 3 0 Lipoprotein leucine-zipper SKA2 PF16740.5 RLN90726.1 - 7.4 6.4 10.4 0.47 10.2 0.3 3.5 5 0 0 5 5 5 0 Spindle and kinetochore-associated protein 2 EF-hand_1 PF00036.32 RLN90732.1 - 0.00024 20.4 3.3 0.18 11.4 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN90732.1 - 0.0012 18.6 1.0 1 9.5 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RLN90732.1 - 0.0019 18.6 0.6 4.7 7.7 0.0 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN90732.1 - 0.02 14.3 9.9 0.61 9.7 0.1 2.9 3 0 0 3 3 3 0 EF hand VCBS PF13517.6 RLN90732.1 - 0.025 15.2 3.2 1.5 9.5 0.2 2.9 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Asp-B-Hydro_N PF05279.11 RLN90732.1 - 0.057 13.5 0.2 0.54 10.3 0.1 2.2 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region PEPCK_ATP PF01293.20 RLN90733.1 - 6.8e-92 308.6 0.1 7.9e-92 308.3 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase PDZ_1 PF12812.7 RLN90733.1 - 0.17 11.9 0.0 0.93 9.6 0.0 2.1 2 0 0 2 2 2 0 PDZ-like domain HSP90 PF00183.18 RLN90734.1 - 2e-15 56.7 13.6 2.6e-15 56.3 13.6 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 RLN90734.1 - 1.7e-14 54.3 0.0 2.4e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 RLN90734.1 - 4.3e-10 39.5 0.3 8.5e-10 38.6 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_pol3_a_NII PF11490.8 RLN90734.1 - 0.046 13.6 7.3 0.077 12.9 7.3 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II ABC2_membrane PF01061.24 RLN90736.1 - 5e-29 101.2 27.3 5e-29 101.2 27.3 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RLN90736.1 - 3.1e-17 63.4 0.0 7.2e-17 62.2 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 RLN90736.1 - 1.7e-05 24.8 0.0 0.034 14.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN90736.1 - 0.0021 18.0 0.4 0.0045 16.9 0.4 1.5 1 0 0 1 1 1 1 RsgA GTPase PDR_assoc PF08370.11 RLN90736.1 - 0.0028 17.4 0.8 0.0081 15.9 0.8 1.8 1 0 0 1 1 1 1 Plant PDR ABC transporter associated AAA_29 PF13555.6 RLN90736.1 - 0.0043 16.8 1.3 0.011 15.5 1.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN90736.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 RLN90736.1 - 0.085 12.4 0.2 0.19 11.3 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 RLN90736.1 - 0.1 13.0 0.7 0.2 12.1 0.7 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 RLN90736.1 - 0.11 12.0 0.5 14 5.0 0.2 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF1422 PF07226.11 RLN90736.1 - 0.68 10.0 4.5 17 5.4 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) Cellulase PF00150.18 RLN90737.1 - 4.7e-07 29.5 6.7 7.6e-05 22.3 2.4 2.1 1 1 1 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Peptidase_S78_2 PF14550.6 RLN90737.1 - 0.012 15.7 0.1 0.019 15.0 0.1 1.3 1 0 0 1 1 1 0 Putative phage serine protease XkdF Glutaredoxin2_C PF04399.13 RLN90738.1 - 9.4e-48 161.3 0.0 1.2e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_N_3 PF13417.6 RLN90738.1 - 1.7e-09 38.0 0.0 3.5e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN90738.1 - 2.6e-06 27.6 0.0 5.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 RLN90738.1 - 0.0089 16.2 0.2 0.05 13.8 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin GST_N_4 PF17172.4 RLN90738.1 - 0.11 13.3 0.0 0.26 12.0 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Glutaredoxin2_C PF04399.13 RLN90739.1 - 7.4e-46 155.2 0.1 9.6e-46 154.8 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_N_3 PF13417.6 RLN90739.1 - 8.9e-13 48.5 0.0 1.8e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN90739.1 - 5.1e-08 33.1 0.0 9.4e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RLN90739.1 - 0.00031 21.0 0.2 0.0022 18.3 0.0 2.4 2 2 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 RLN90739.1 - 0.0041 17.3 0.0 0.0093 16.2 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_4 PF17172.4 RLN90739.1 - 0.031 15.0 0.0 0.071 13.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Fic PF02661.18 RLN90740.1 - 2.1e-13 50.9 0.0 5.5e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Fic/DOC family MIP PF00230.20 RLN90741.1 - 7.6e-12 45.4 0.9 1.1e-11 44.9 0.9 1.2 1 1 0 1 1 1 1 Major intrinsic protein Ank_4 PF13637.6 RLN90742.1 - 3e-23 81.9 10.5 1.7e-05 25.3 0.0 5.2 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN90742.1 - 6e-19 68.4 0.9 3.7e-07 30.7 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN90742.1 - 8.6e-19 67.4 8.0 0.022 15.1 0.1 7.7 2 1 6 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN90742.1 - 2e-12 46.1 1.4 5.8 7.8 0.0 7.7 7 1 1 8 8 8 3 Ankyrin repeat MIF PF01187.18 RLN90742.1 - 5.9e-09 36.2 0.0 1.1e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 RLN90742.1 - 3.4e-05 23.7 0.0 0.00063 19.6 0.0 2.4 2 0 0 2 2 2 1 Tautomerase enzyme DUF5049 PF16468.5 RLN90742.1 - 0.0024 17.7 0.7 46 4.0 0.0 5.4 3 3 3 6 6 6 0 Domain of unknown function (DUF5049) Ank PF00023.30 RLN90742.1 - 0.0048 17.3 0.1 55 4.5 0.1 5.4 2 1 1 3 3 3 0 Ankyrin repeat DUF1843 PF08898.10 RLN90742.1 - 0.13 12.8 4.7 10 6.7 0.0 4.4 5 1 1 6 6 6 0 Domain of unknown function (DUF1843) VbhA PF18495.1 RLN90742.1 - 1.8 8.5 5.9 48 3.9 0.0 4.3 5 0 0 5 5 5 0 Antitoxin VbhA Pkinase_Tyr PF07714.17 RLN90743.1 - 1.9e-21 76.6 0.0 1.5e-20 73.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_1 PF00515.28 RLN90743.1 - 1e-20 72.6 17.5 0.00012 21.7 0.5 8.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 RLN90743.1 - 2.5e-19 67.8 25.6 0.001 19.0 0.5 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat Pkinase PF00069.25 RLN90743.1 - 1.2e-17 64.1 0.0 1e-16 61.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain TPR_11 PF13414.6 RLN90743.1 - 1.4e-13 50.3 17.6 1.4e-06 27.9 0.4 6.7 5 2 2 7 7 7 3 TPR repeat TPR_8 PF13181.6 RLN90743.1 - 2e-12 46.3 16.6 0.21 11.9 0.4 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 RLN90743.1 - 9.4e-11 42.1 11.5 0.021 15.3 0.3 6.6 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 RLN90743.1 - 1.3e-09 38.1 21.1 0.22 12.4 1.2 8.3 6 2 2 9 9 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 RLN90743.1 - 4.9e-06 26.6 7.2 0.14 12.6 0.1 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN90743.1 - 0.00014 21.9 14.1 0.12 12.5 2.4 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.6 RLN90743.1 - 0.0022 18.3 10.7 0.091 13.1 0.2 4.8 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN90743.1 - 0.0023 17.8 13.3 1.2 9.3 0.1 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN90743.1 - 0.0063 16.8 23.7 0.75 10.1 0.1 6.9 4 2 2 6 6 6 1 Tetratricopeptide repeat APH PF01636.23 RLN90743.1 - 0.014 15.3 0.2 0.014 15.3 0.2 3.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family MIT PF04212.18 RLN90743.1 - 0.055 13.5 4.5 11 6.2 0.3 4.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 RLN90743.1 - 0.11 13.2 28.4 0.33 11.6 0.3 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 RLN90743.1 - 0.31 11.8 6.4 1.1 10.1 2.0 4.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN90743.1 - 2.7 8.8 16.3 5.3 7.9 1.3 5.4 5 0 0 5 5 4 0 Tetratricopeptide repeat Ribosomal_L18A PF01775.17 RLN90744.1 - 5.1e-44 149.3 0.7 3.4e-25 88.5 0.2 2.6 2 0 0 2 2 2 2 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A MIF PF01187.18 RLN90744.1 - 1.2e-19 70.7 0.1 1.9e-19 70.0 0.1 1.4 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Ank_2 PF12796.7 RLN90744.1 - 1.7e-09 38.1 1.1 9.5e-05 22.9 0.1 2.8 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Tautomerase PF01361.21 RLN90744.1 - 3.7e-05 23.5 0.1 0.00041 20.2 0.0 2.5 2 0 0 2 2 2 1 Tautomerase enzyme Ank_4 PF13637.6 RLN90744.1 - 0.012 16.2 0.3 0.88 10.2 0.2 3.4 3 1 1 4 4 3 0 Ankyrin repeats (many copies) Ndc80_HEC PF03801.13 RLN90744.1 - 0.029 14.0 0.0 0.18 11.5 0.0 2.1 1 1 1 2 2 2 0 HEC/Ndc80p family Tautomerase_2 PF14552.6 RLN90744.1 - 0.034 14.2 0.1 11 6.2 0.0 3.2 2 1 1 3 3 3 0 Tautomerase enzyme DHC PF09626.10 RLN90744.1 - 0.044 14.7 0.0 0.14 13.1 0.0 1.9 1 0 0 1 1 1 0 Dihaem cytochrome c DUF4228 PF14009.6 RLN90744.1 - 0.048 14.0 0.1 0.097 13.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Ank_5 PF13857.6 RLN90744.1 - 0.053 13.9 0.4 12 6.4 0.0 3.6 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN90745.1 - 4.6e-46 155.3 14.0 3.4e-10 40.4 0.0 7.0 2 2 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN90745.1 - 1.8e-39 133.6 22.9 2.1e-06 28.2 0.1 11.3 6 3 8 14 14 14 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN90745.1 - 3.4e-34 116.4 22.0 0.00087 19.6 0.1 14.2 6 2 10 16 16 16 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN90745.1 - 3.5e-25 85.3 4.8 0.3 11.8 0.0 15.3 12 3 4 16 16 16 4 Ankyrin repeat DUF5049 PF16468.5 RLN90745.1 - 3.8e-06 26.7 0.0 3.4 7.6 0.0 7.8 7 3 3 10 10 10 1 Domain of unknown function (DUF5049) Ank PF00023.30 RLN90745.1 - 5.1e-05 23.5 4.9 77 4.0 0.1 8.5 4 2 3 7 7 7 0 Ankyrin repeat Kunitz_BPTI PF00014.23 RLN90745.1 - 0.027 14.7 0.4 3.6 7.9 0.0 4.3 2 1 3 6 6 6 0 Kunitz/Bovine pancreatic trypsin inhibitor domain DUF1843 PF08898.10 RLN90745.1 - 0.1 13.1 2.7 10 6.7 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) LZ_Tnp_IS481 PF13011.6 RLN90745.1 - 1.9 9.0 4.4 8.8 6.9 0.1 4.0 2 2 4 6 6 6 0 leucine-zipper of insertion element IS481 SET PF00856.28 RLN90746.1 - 5.3e-12 46.4 0.0 5.3e-06 26.9 0.0 2.5 2 0 0 2 2 2 2 SET domain Rubis-subs-bind PF09273.11 RLN90746.1 - 9.9e-10 39.2 3.0 1.4e-09 38.7 1.0 2.3 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding DUF4661 PF15576.6 RLN90748.1 - 0.46 10.4 3.1 0.58 10.0 3.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) DUF5391 PF17369.2 RLN90749.1 - 0.042 13.9 1.0 0.042 13.9 1.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5391) LRR_6 PF13516.6 RLN90750.1 - 5.8e-27 91.4 14.8 9.7e-05 22.1 0.1 9.3 10 0 0 10 10 10 6 Leucine Rich repeat LRR_4 PF12799.7 RLN90750.1 - 1.1e-10 41.6 13.5 0.24 11.9 0.0 7.0 3 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN90750.1 - 5e-07 29.4 0.0 7.4 7.5 0.1 7.8 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.6 RLN90750.1 - 8.5e-05 22.2 11.4 0.12 12.1 0.6 6.3 4 2 1 5 5 5 2 Leucine rich repeat TPD52 PF04201.15 RLN90751.1 - 0.16 11.5 0.1 0.77 9.3 0.0 2.0 2 0 0 2 2 2 0 Tumour protein D52 family CT_C_D PF02682.16 RLN90752.1 - 3.9 7.2 4.7 15 5.2 1.0 2.8 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D Aa_trans PF01490.18 RLN90753.1 - 0.17 10.5 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein HD_5 PF13487.6 RLN90754.1 - 0.05 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 HD domain Occludin_ELL PF07303.13 RLN90754.1 - 0.75 10.6 3.6 2.9 8.7 0.4 2.4 2 0 0 2 2 2 0 Occludin homology domain His_Phos_1 PF00300.22 RLN90755.1 - 2e-16 60.3 0.0 6.5e-16 58.6 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Kin17_mid PF10357.9 RLN90756.1 - 1.4e-47 160.7 1.2 1.4e-47 160.7 1.2 2.2 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 RLN90756.1 - 2.5e-25 88.4 2.1 5.8e-25 87.2 2.1 1.7 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain zf-met PF12874.7 RLN90756.1 - 0.004 17.5 5.0 0.0071 16.7 5.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RLN90756.1 - 0.025 14.9 4.8 0.044 14.1 4.8 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 RLN90756.1 - 0.32 11.4 3.0 0.23 11.8 0.6 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF572 PF04502.13 RLN90756.1 - 2.4 7.7 10.5 4.1 6.9 10.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DHHC PF01529.20 RLN90757.1 - 2e-28 99.1 11.5 2e-28 99.1 11.5 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase Voltage_CLC PF00654.20 RLN90757.1 - 0.015 14.6 0.6 0.021 14.1 0.6 1.2 1 0 0 1 1 1 0 Voltage gated chloride channel Spt4 PF06093.13 RLN90757.1 - 0.26 11.4 6.3 0.47 10.6 6.3 1.4 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Phage_holin_3_6 PF07332.11 RLN90757.1 - 1.1 9.3 7.5 1.4 8.9 0.4 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III THOC7 PF05615.13 RLN90758.1 - 1.3e-08 35.2 0.2 1.7e-08 34.8 0.2 1.0 1 0 0 1 1 1 1 Tho complex subunit 7 DUF4817 PF16087.5 RLN90758.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) RXT2_N PF08595.11 RLN90759.1 - 0.01 15.9 3.2 0.012 15.7 3.2 1.0 1 0 0 1 1 1 0 RXT2-like, N-terminal HCMV_UL139 PF12507.8 RLN90759.1 - 0.031 14.6 0.9 0.039 14.3 0.9 1.1 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein HAUS6_N PF14661.6 RLN90759.1 - 0.22 11.1 5.4 0.25 10.9 5.4 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus PCYCGC PF13798.6 RLN90759.1 - 2.9 7.7 6.2 8.7 6.2 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function with PCYCGC motif IQ PF00612.27 RLN90760.1 - 9.1 6.4 7.7 0.68 9.9 2.3 2.0 2 0 0 2 2 2 0 IQ calmodulin-binding motif His_Phos_1 PF00300.22 RLN90761.1 - 2.6e-12 46.9 0.1 8.6e-12 45.1 0.1 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Arm PF00514.23 RLN90762.1 - 8.6e-06 25.6 0.1 0.0062 16.5 0.0 3.0 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Cutinase PF01083.22 RLN90762.1 - 0.00029 20.8 0.0 0.0008 19.4 0.0 1.7 2 0 0 2 2 2 1 Cutinase Abhydrolase_6 PF12697.7 RLN90762.1 - 0.0003 21.4 0.0 0.00056 20.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family HEAT_2 PF13646.6 RLN90762.1 - 0.00081 19.7 0.9 1.7 9.1 0.0 2.5 2 0 0 2 2 2 2 HEAT repeats V-ATPase_H_N PF03224.14 RLN90762.1 - 0.0075 15.6 0.1 0.013 14.8 0.1 1.4 1 0 0 1 1 1 1 V-ATPase subunit H HEAT PF02985.22 RLN90762.1 - 0.014 15.6 0.2 0.18 12.2 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat PGAP1 PF07819.13 RLN90762.1 - 0.017 14.8 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Cnd1 PF12717.7 RLN90762.1 - 0.034 14.2 0.0 0.1 12.7 0.0 1.8 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 DUF676 PF05057.14 RLN90762.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) zf-UBR PF02207.20 RLN90764.1 - 3.5e-13 49.5 10.4 3.5e-13 49.5 10.4 3.8 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.29 RLN90764.1 - 0.053 13.4 0.6 0.053 13.4 0.6 3.8 4 1 0 4 4 4 0 PHD-finger zf-LYAR PF08790.11 RLN90765.1 - 3.9e-14 52.2 2.7 3.9e-14 52.2 2.7 2.6 3 0 0 3 3 3 1 LYAR-type C2HC zinc finger VPS11_C PF12451.8 RLN90765.1 - 0.18 12.0 2.9 0.2 11.9 1.6 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal C1_4 PF07975.12 RLN90765.1 - 0.22 11.8 4.4 0.73 10.1 4.4 1.9 1 0 0 1 1 1 0 TFIIH C1-like domain zinc_ribbon_12 PF11331.8 RLN90765.1 - 0.56 10.1 2.6 1.5 8.7 2.6 1.7 1 0 0 1 1 1 0 Probable zinc-ribbon domain PX PF00787.24 RLN90766.1 - 1.9e-13 50.4 0.1 2.9e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 PX domain GOLD_2 PF13897.6 RLN90766.1 - 0.0015 19.1 0.0 0.003 18.1 0.0 1.5 1 0 0 1 1 1 1 Golgi-dynamics membrane-trafficking Thioredoxin PF00085.20 RLN90767.1 - 1.2e-21 76.6 0.2 3e-21 75.3 0.2 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 RLN90767.1 - 0.00018 21.9 1.8 0.0096 16.4 0.1 3.0 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RLN90767.1 - 0.0039 17.5 0.0 0.0071 16.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 RLN90767.1 - 0.0063 16.4 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 RLN90767.1 - 0.038 13.3 0.1 0.067 12.5 0.1 1.4 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 RLN90767.1 - 0.19 11.5 0.1 0.19 11.5 0.1 2.6 3 0 0 3 3 3 0 Thioredoxin Use1 PF09753.9 RLN90767.1 - 1.2 8.8 11.2 1.5 8.4 11.2 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 Oxidored_FMN PF00724.20 RLN90768.1 - 7.8e-88 295.0 0.0 1e-87 294.6 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 RLN90768.1 - 7.5e-26 91.0 1.6 1.4e-25 90.1 1.6 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RLN90768.1 - 8.7e-10 38.7 0.5 4.3e-09 36.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 RLN90768.1 - 1.7e-09 38.1 6.1 7.2e-05 23.3 0.8 3.9 3 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RLN90768.1 - 1.5e-07 31.0 1.2 0.0016 17.8 0.0 2.8 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RLN90768.1 - 6.9e-07 28.3 1.4 1.7e-06 27.0 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 RLN90768.1 - 8.4e-06 25.1 1.3 2.3e-05 23.6 0.7 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 RLN90768.1 - 2.8e-05 23.7 0.0 4.3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 RLN90768.1 - 3.8e-05 23.6 2.4 0.002 18.0 0.1 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 RLN90768.1 - 0.00027 20.7 0.7 0.00027 20.7 0.7 4.0 3 2 1 5 5 5 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 RLN90768.1 - 0.00075 18.8 1.2 0.026 13.8 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain FMO-like PF00743.19 RLN90768.1 - 0.0012 17.4 0.0 0.029 12.8 0.0 2.6 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like UDPG_MGDP_dh_N PF03721.14 RLN90768.1 - 0.0036 16.9 0.1 0.08 12.5 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 RLN90768.1 - 0.0038 17.2 0.3 0.57 10.2 0.0 2.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.22 RLN90768.1 - 0.004 16.3 0.4 0.004 16.3 0.4 1.8 3 0 0 3 3 2 1 Glucose inhibited division protein A Thi4 PF01946.17 RLN90768.1 - 0.0049 16.1 0.3 0.014 14.6 0.0 1.9 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.19 RLN90768.1 - 0.0051 16.2 1.0 0.9 8.9 0.0 3.1 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN90768.1 - 0.033 13.5 0.3 0.033 13.5 0.3 2.5 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 RLN90768.1 - 0.045 13.7 6.6 0.12 12.4 0.1 3.4 4 0 0 4 4 4 0 FAD-NAD(P)-binding ThiF PF00899.21 RLN90768.1 - 0.058 12.8 0.1 0.85 8.9 0.1 2.2 2 0 0 2 2 2 0 ThiF family ApbA PF02558.16 RLN90768.1 - 0.14 11.8 2.7 28 4.3 0.0 3.5 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 RLN90768.1 - 0.23 12.1 0.9 35 5.1 0.0 2.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Lycopene_cycl PF05834.12 RLN90768.1 - 0.29 10.2 2.2 0.17 10.9 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein ATP_bind_3 PF01171.20 RLN90769.1 - 5e-36 124.2 0.0 8e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF924 PF06041.11 RLN90769.1 - 6.2e-22 78.6 0.3 1.1e-21 77.8 0.3 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) QueC PF06508.13 RLN90769.1 - 4.7e-06 26.3 0.0 0.0017 17.9 0.0 2.5 2 0 0 2 2 2 2 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 RLN90769.1 - 2.3e-05 24.3 0.5 6.8e-05 22.7 0.0 1.9 1 1 1 2 2 2 1 Asparagine synthase tRNA_Me_trans PF03054.16 RLN90769.1 - 0.00044 19.2 0.0 0.0007 18.5 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 RLN90769.1 - 0.00049 19.7 0.0 0.0046 16.6 0.0 2.2 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.17 RLN90769.1 - 0.016 14.4 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD synthase PAPS_reduct PF01507.19 RLN90769.1 - 0.025 14.6 0.0 0.1 12.6 0.0 2.0 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family RNA_pol_Rpb5_C PF01191.19 RLN90770.1 - 8.7e-32 108.8 0.1 1.6e-31 108.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 RLN90770.1 - 2e-27 95.6 0.0 3.2e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain DUF1325 PF07039.11 RLN90771.1 - 0.0015 18.6 0.1 0.0025 17.9 0.1 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain Agenet PF05641.12 RLN90771.1 - 0.0034 17.8 0.0 0.013 15.9 0.0 2.0 2 0 0 2 2 2 1 Agenet domain TUDOR_5 PF18359.1 RLN90771.1 - 0.011 15.4 0.1 0.023 14.4 0.1 1.5 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 DTHCT PF08070.11 RLN90771.1 - 0.02 15.6 4.7 0.11 13.2 0.3 2.2 2 0 0 2 2 2 0 DTHCT (NUC029) region Tcp10_C PF07202.13 RLN90771.1 - 0.024 14.6 0.6 0.063 13.2 0.3 2.0 2 1 0 2 2 2 0 T-complex protein 10 C-terminus LBR_tudor PF09465.10 RLN90771.1 - 0.14 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain DUF3408 PF11888.8 RLN90771.1 - 0.21 11.7 2.1 2.1 8.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) ATP-synt_Eps PF04627.13 RLN90772.1 - 6.5e-17 61.2 0.2 9.6e-17 60.7 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain IBR PF01485.21 RLN90773.1 - 2.1e-14 53.5 48.8 5.2e-09 36.2 12.0 4.3 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain DUF3138 PF11336.8 RLN90773.1 - 0.023 13.3 2.3 0.034 12.8 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) zf-RING_2 PF13639.6 RLN90773.1 - 0.03 14.7 7.8 0.03 14.7 7.8 4.2 3 1 0 3 3 3 0 Ring finger domain Wyosine_form PF08608.12 RLN90775.1 - 1.6e-26 92.4 0.0 4e-26 91.1 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 RLN90775.1 - 7.2e-23 81.8 0.0 1.3e-22 81.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 RLN90775.1 - 5.7e-18 65.5 1.9 8.7e-18 64.9 0.1 2.1 2 0 0 2 2 2 1 Flavodoxin NDK PF00334.19 RLN90776.1 - 9.7e-29 100.1 0.0 1.3e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Peptidase_M13 PF01431.21 RLN90778.1 - 3.9e-20 72.3 0.0 4.3e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 ABC2_membrane PF01061.24 RLN90779.1 - 4.1e-62 209.3 62.2 1e-36 126.4 25.5 2.5 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN90779.1 - 7.2e-36 123.7 0.1 2.6e-17 63.6 0.0 2.2 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 RLN90779.1 - 1e-08 34.9 5.3 1.2e-07 31.5 0.0 3.3 3 0 0 3 3 3 1 CDR ABC transporter AAA_16 PF13191.6 RLN90779.1 - 5.1e-08 33.5 1.8 0.0062 16.9 0.1 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 RLN90779.1 - 9.5e-08 32.2 0.0 0.085 12.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN90779.1 - 4.9e-06 26.6 1.4 0.016 15.1 0.4 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 RLN90779.1 - 9.7e-06 25.3 0.1 0.16 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 RLN90779.1 - 1.4e-05 24.8 6.3 0.021 14.5 1.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN90779.1 - 0.00015 22.4 0.1 0.35 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RLN90779.1 - 0.00016 21.9 0.1 0.62 10.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain SMC_N PF02463.19 RLN90779.1 - 0.0003 20.3 0.7 0.38 10.2 0.0 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 RLN90779.1 - 0.00089 19.0 0.1 1.3 8.7 0.1 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN90779.1 - 0.0034 16.7 1.9 0.26 10.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.29 RLN90779.1 - 0.0072 16.8 0.1 7.6 7.0 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 RLN90779.1 - 0.0074 16.4 0.2 2.7 8.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 RLN90779.1 - 0.0092 15.9 1.7 2.5 8.0 0.1 2.6 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 RLN90779.1 - 0.011 16.3 0.1 5.3 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 RLN90779.1 - 0.014 14.2 0.3 0.43 9.3 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class cobW PF02492.19 RLN90779.1 - 0.023 14.3 0.8 1.8 8.1 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PDR_assoc PF08370.11 RLN90779.1 - 0.032 14.0 0.3 0.032 14.0 0.3 4.2 5 0 0 5 5 3 0 Plant PDR ABC transporter associated AAA_33 PF13671.6 RLN90779.1 - 0.035 14.3 0.1 4.1 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 RLN90779.1 - 0.036 14.0 0.3 0.46 10.4 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 RLN90779.1 - 0.07 13.5 0.2 9.9 6.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ABC2_membrane_3 PF12698.7 RLN90779.1 - 0.084 12.0 47.7 0.065 12.3 11.6 3.2 2 2 1 3 3 3 0 ABC-2 family transporter protein DUF87 PF01935.17 RLN90779.1 - 0.088 12.9 4.1 1.3 9.1 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_5 PF07728.14 RLN90779.1 - 0.097 12.7 0.4 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Roc PF08477.13 RLN90779.1 - 0.17 12.1 0.6 13 6.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 RLN90779.1 - 0.18 11.7 0.0 6.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain PduV-EutP PF10662.9 RLN90779.1 - 0.3 10.8 0.8 5.2 6.8 0.3 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase PF06745.13 RLN90779.1 - 0.39 10.0 1.0 6.5 6.0 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 RLN90779.1 - 0.72 9.5 1.7 16 5.2 0.5 2.3 2 0 0 2 2 2 0 AAA domain Kinesin PF00225.23 RLN90780.1 - 2.8e-86 289.5 3.2 3.9e-51 174.0 0.0 2.9 2 1 1 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 RLN90780.1 - 6.8e-25 87.8 0.0 1.8e-24 86.4 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 RLN90780.1 - 0.00032 20.9 0.4 0.00032 20.9 0.4 3.8 2 2 1 3 3 3 1 Kinesin-associated LRR_3 PF07725.12 RLN90780.1 - 0.17 11.8 0.1 0.47 10.4 0.1 1.8 2 0 0 2 2 2 0 Leucine Rich Repeat CheD PF03975.13 RLN90780.1 - 0.18 11.9 3.7 0.13 12.3 0.3 2.4 2 0 0 2 2 2 0 CheD chemotactic sensory transduction Kinesin PF00225.23 RLN90781.1 - 6.5e-87 291.6 0.4 1.8e-86 290.1 0.3 1.7 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN90781.1 - 9.6e-20 71.0 0.0 1.3e-18 67.4 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding DUF3500 PF12006.8 RLN90781.1 - 0.093 12.2 2.0 0.12 11.9 1.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3500) Fringe PF02434.16 RLN90782.1 - 1.3e-14 54.2 0.1 1.9e-14 53.7 0.1 1.2 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.12 RLN90782.1 - 0.0099 15.3 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Galactosyl_T PF01762.21 RLN90782.1 - 0.15 11.9 0.0 0.4 10.5 0.0 1.7 2 0 0 2 2 2 0 Galactosyltransferase DUF4097 PF13349.6 RLN90783.1 - 0.013 14.8 2.2 0.02 14.3 1.8 1.4 1 1 0 1 1 1 0 Putative adhesin Tetraspanin PF00335.20 RLN90783.1 - 1.5 8.5 18.9 2.5 7.7 14.3 2.7 1 1 1 2 2 2 0 Tetraspanin family DUF4418 PF14387.6 RLN90783.1 - 4.4 7.5 12.4 0.53 10.5 2.9 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4418) HUN PF08729.10 RLN90784.1 - 1e-09 38.3 6.1 1.9e-09 37.4 6.1 1.4 1 0 0 1 1 1 1 HPC2 and ubinuclein domain PWI PF01480.17 RLN90786.1 - 1.3e-26 92.7 0.3 2.8e-26 91.6 0.3 1.6 1 0 0 1 1 1 1 PWI domain MMADHC PF10229.9 RLN90786.1 - 6e-26 91.8 0.0 1.6e-25 90.4 0.0 1.6 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein tRNA_U5-meth_tr PF05958.11 RLN90787.1 - 1e-18 67.5 0.1 2.9e-18 66.0 0.0 1.8 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 RLN90787.1 - 8e-05 23.3 0.1 0.00031 21.4 0.1 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN90787.1 - 0.00012 21.9 0.0 0.00012 21.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 RLN90787.1 - 0.00031 20.3 0.4 0.00031 20.3 0.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 RLN90787.1 - 0.0041 16.7 0.1 0.011 15.2 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 RLN90787.1 - 0.0074 15.8 0.1 0.0074 15.8 0.1 1.9 2 0 0 2 2 1 1 Putative methyltransferase Cons_hypoth95 PF03602.15 RLN90787.1 - 0.0084 15.8 0.6 0.017 14.8 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_32 PF13679.6 RLN90787.1 - 0.027 14.4 0.0 0.027 14.4 0.0 3.0 3 0 0 3 3 3 0 Methyltransferase domain AviRa PF11599.8 RLN90787.1 - 0.096 12.1 0.1 0.096 12.1 0.1 2.1 2 0 0 2 2 1 0 RRNA methyltransferase AviRa Ubie_methyltran PF01209.18 RLN90787.1 - 0.14 11.5 0.3 0.25 10.6 0.3 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Tho2 PF11262.8 RLN90787.1 - 0.63 9.2 5.5 1.2 8.3 5.5 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 V_ATPase_I PF01496.19 RLN90787.1 - 1.9 6.3 5.9 3.1 5.6 5.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3449 PF11931.8 RLN90787.1 - 2.5 7.8 9.8 0.24 11.2 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) PBP1_TM PF14812.6 RLN90787.1 - 3.7 8.0 16.0 8.7 6.8 6.3 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CCDC71L PF15374.6 RLN90787.1 - 4.1 6.6 12.2 7.9 5.6 12.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L N6_Mtase PF02384.16 RLN90787.1 - 8 5.6 8.5 0.85 8.8 0.1 2.5 2 0 0 2 2 2 0 N-6 DNA Methylase Presenilin PF01080.17 RLN90787.1 - 8.8 5.0 7.6 15 4.2 7.6 1.3 1 0 0 1 1 1 0 Presenilin ABC1 PF03109.16 RLN90788.1 - 3.1e-22 79.0 0.0 5.5e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 RLN90788.1 - 1.7e-07 30.9 0.0 0.0074 15.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 RLN90788.1 - 0.00059 19.8 0.1 0.00059 19.8 0.1 3.0 2 2 0 2 2 2 1 Phosphotransferase enzyme family Ank_2 PF12796.7 RLN90789.1 - 9e-13 48.6 0.2 0.0014 19.1 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN90789.1 - 1.9e-09 37.9 0.1 0.0074 16.8 0.0 2.9 2 2 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN90789.1 - 7.5e-09 35.7 0.0 0.00071 19.9 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RLN90789.1 - 3.1e-08 33.7 0.6 0.21 12.0 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN90789.1 - 5.2e-06 26.4 0.3 0.0058 17.0 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Sel1 PF08238.12 RLN90790.1 - 8.3e-42 140.7 18.2 1e-08 35.6 0.9 6.2 6 0 0 6 6 6 6 Sel1 repeat B12-binding_2 PF02607.17 RLN90790.1 - 0.044 14.2 1.0 1.3 9.5 0.8 3.1 2 1 0 2 2 2 0 B12 binding domain DUF3703 PF12487.8 RLN90790.1 - 0.067 13.0 1.9 0.23 11.3 1.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3703) TPR_1 PF00515.28 RLN90790.1 - 0.12 12.2 7.1 7.9 6.5 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 RLN90790.1 - 0.3 10.8 6.5 21 4.9 0.0 4.5 4 1 0 4 4 4 0 TPR repeat TPR_6 PF13174.6 RLN90790.1 - 0.61 10.8 13.9 68 4.4 0.3 6.2 5 1 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN90790.1 - 1.9 8.8 0.0 1.9 8.8 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Cys_Met_Meta_PP PF01053.20 RLN90791.1 - 8.4e-155 515.0 0.0 9.5e-155 514.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 RLN90791.1 - 4e-08 32.8 0.0 5.9e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 RLN90791.1 - 7.4e-05 22.2 1.3 0.00033 20.1 1.1 2.0 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 RLN90791.1 - 0.0023 17.3 0.2 0.0075 15.6 0.2 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 RLN90791.1 - 0.0044 15.6 0.0 0.0056 15.2 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase MHB PF16525.5 RLN90791.1 - 0.07 13.4 0.3 0.48 10.7 0.2 2.2 2 0 0 2 2 2 0 Haemophore, haem-binding Acetyltransf_7 PF13508.7 RLN90793.1 - 5.2e-06 26.8 0.0 6.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RLN90793.1 - 2.3e-05 24.4 0.1 0.0002 21.3 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RLN90793.1 - 0.00056 20.1 0.0 0.0008 19.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 RLN90793.1 - 0.0075 16.2 0.0 0.022 14.7 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 RLN90793.1 - 0.012 15.7 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_16 PF05301.11 RLN90793.1 - 0.054 13.3 0.0 0.067 13.0 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 FUSC-like PF12805.7 RLN90793.1 - 0.081 12.0 0.0 0.085 11.9 0.0 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS C2 PF00168.30 RLN90794.1 - 3e-12 46.7 0.0 4.7e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 C2 domain YwiC PF14256.6 RLN90794.1 - 0.0056 17.0 3.8 0.0056 17.0 3.8 2.2 1 1 1 2 2 2 1 YwiC-like protein DUF2207 PF09972.9 RLN90794.1 - 0.23 10.2 0.5 0.3 9.8 0.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phage_holin_3_6 PF07332.11 RLN90794.1 - 0.4 10.7 9.3 0.81 9.8 9.3 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Sulfotransfer_2 PF03567.14 RLN90795.1 - 1.1 9.1 6.3 0.56 10.1 2.8 2.1 2 0 0 2 2 2 0 Sulfotransferase family Iron_permease PF04120.12 RLN90795.1 - 5.1 6.9 7.5 1.1 9.1 3.3 2.1 2 0 0 2 2 2 0 Low affinity iron permease Pkinase_Tyr PF07714.17 RLN90796.1 - 1.7e-67 227.5 0.0 2.1e-67 227.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN90796.1 - 3.9e-56 190.4 0.0 5.4e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RLN90796.1 - 0.00025 20.5 0.0 0.00045 19.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RLN90796.1 - 0.033 13.1 0.1 0.46 9.4 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain COesterase PF00135.28 RLN90799.1 - 1.8e-90 304.3 0.0 2.2e-90 304.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RLN90799.1 - 7.7e-05 22.6 0.4 0.0011 18.8 0.4 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN90799.1 - 0.0081 15.7 0.2 0.016 14.7 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF3102 PF11300.8 RLN90799.1 - 0.22 11.8 0.0 0.39 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3102) Aa_trans PF01490.18 RLN90801.1 - 6.2e-39 133.9 14.7 1e-38 133.1 14.7 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF5383 PF17355.2 RLN90801.1 - 0.38 11.1 0.1 0.38 11.1 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5383) ATPase_gene1 PF09527.10 RLN90801.1 - 3.3 8.0 8.8 2.3 8.4 3.6 3.2 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Dicty_REP PF05086.12 RLN90802.1 - 2 6.3 3.1 2.3 6.1 3.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Presenilin PF01080.17 RLN90802.1 - 9.6 4.9 5.2 11 4.7 5.2 1.1 1 0 0 1 1 1 0 Presenilin Atx10homo_assoc PF09759.9 RLN90804.1 - 8.3e-05 22.5 0.2 0.11 12.5 0.1 2.1 1 1 1 2 2 2 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 RLN90804.1 - 0.0066 16.5 0.0 0.039 14.0 0.0 2.2 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat Peptidase_M1_N PF17900.1 RLN90805.1 - 9.2e-23 81.4 0.0 1.2e-22 81.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 RLN90805.1 - 0.15 12.0 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) ZapB PF06005.12 RLN90808.1 - 0.0089 16.5 0.4 0.0089 16.5 0.4 3.3 3 0 0 3 3 3 1 Cell division protein ZapB YabA PF06156.13 RLN90808.1 - 1.6 9.4 5.0 13 6.5 0.2 3.2 3 0 0 3 3 3 0 Initiation control protein YabA Pkinase_Tyr PF07714.17 RLN90810.1 - 1.3e-22 80.4 0.0 3.8e-07 29.7 0.0 6.4 4 2 0 4 4 4 3 Protein tyrosine kinase Pkinase PF00069.25 RLN90810.1 - 8.1e-15 54.9 0.0 0.00051 19.5 0.0 5.5 3 2 1 4 4 4 3 Protein kinase domain Urocanase_C PF17392.2 RLN90811.1 - 3.5e-87 290.9 1.6 5.5e-87 290.3 1.6 1.3 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase PF01175.18 RLN90811.1 - 2.5e-70 236.4 0.0 4.4e-70 235.6 0.0 1.4 1 0 0 1 1 1 1 Urocanase Rossmann-like domain MULE PF10551.9 RLN90812.1 - 2.5e-12 47.0 0.1 7e-12 45.6 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 RLN90812.1 - 0.021 15.5 0.1 0.051 14.3 0.1 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain CTP_transf_like PF01467.26 RLN90813.1 - 4e-08 33.6 0.3 1.4e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 Cytidylyltransferase-like DivIC PF04977.15 RLN90813.1 - 0.006 16.3 0.2 0.0099 15.6 0.2 1.3 1 0 0 1 1 1 1 Septum formation initiator DUF2919 PF11143.8 RLN90813.1 - 0.0084 16.5 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2919) DUF3247 PF11607.8 RLN90813.1 - 0.094 13.0 0.3 0.16 12.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) TCR PF03638.15 RLN90814.1 - 6e-37 125.7 80.6 8e-13 48.5 20.8 3.2 3 0 0 3 3 3 3 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 RLN90814.1 - 4.6 7.5 68.2 2.3 8.4 17.5 3.5 3 0 0 3 3 3 0 CXC domain of E3 ubiquitin-protein ligase MSL2 Ribosomal_L10 PF00466.20 RLN90815.1 - 1.3e-23 83.0 0.0 3e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 RLN90815.1 - 3.7e-21 74.9 0.4 7.2e-21 74.0 0.3 1.6 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 RLN90815.1 - 2.3e-10 40.9 7.3 5.2e-10 39.8 7.3 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein MMR_HSR1_C PF08438.10 RLN90816.1 - 2e-35 121.7 0.0 3.2e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 RLN90816.1 - 1.9e-20 73.0 0.0 6e-20 71.4 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN90816.1 - 4.3e-09 36.1 0.1 1.1e-07 31.5 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.21 RLN90816.1 - 0.088 12.9 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 TGS domain Dynamin_N PF00350.23 RLN90816.1 - 0.19 11.8 0.1 0.52 10.3 0.0 1.8 2 0 0 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 RLN90816.1 - 0.22 11.3 0.1 21 4.8 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Cpn60_TCP1 PF00118.24 RLN90817.1 - 4.5e-135 451.0 6.8 5.6e-135 450.7 6.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1132 PF06575.12 RLN90817.1 - 0.14 12.6 0.1 0.38 11.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1132) Hydrolase_6 PF13344.6 RLN90819.1 - 3.2e-18 65.7 0.0 6.9e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RLN90819.1 - 1.1e-13 51.0 0.0 3.1e-13 49.6 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 RLN90819.1 - 0.11 12.8 0.0 14 5.9 0.0 2.7 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 RLN90819.1 - 0.23 11.5 0.4 1.1 9.3 0.0 2.3 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Robl_LC7 PF03259.17 RLN90820.1 - 1.6e-20 72.7 0.0 5.7e-20 70.9 0.0 1.9 2 0 0 2 2 2 1 Roadblock/LC7 domain IQ PF00612.27 RLN90820.1 - 0.00092 18.8 0.0 0.0022 17.7 0.0 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif LAMTOR5 PF16672.5 RLN90820.1 - 0.0052 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 SurA_N_3 PF13624.6 RLN90820.1 - 0.025 14.4 1.5 0.055 13.3 1.5 1.6 1 0 0 1 1 1 0 SurA N-terminal domain Sof1 PF04158.14 RLN90820.1 - 0.22 11.8 3.7 5.1 7.4 0.2 2.6 2 0 0 2 2 2 0 Sof1-like domain Arm PF00514.23 RLN90821.1 - 5.9e-25 86.5 23.7 1.6e-06 27.9 0.1 9.1 9 1 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN90821.1 - 6e-10 39.4 5.9 0.00025 21.5 0.2 5.1 4 1 1 5 5 5 3 HEAT-like repeat HEAT_2 PF13646.6 RLN90821.1 - 1.4e-05 25.4 3.0 0.16 12.3 0.1 4.0 2 2 1 3 3 3 2 HEAT repeats NopRA1 PF16201.5 RLN90821.1 - 0.00013 21.7 0.0 5.5 6.5 0.0 4.3 3 2 1 4 4 4 2 Nucleolar pre-ribosomal-associated protein 1 HEAT PF02985.22 RLN90821.1 - 0.00088 19.3 2.8 0.61 10.5 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat DUF659 PF04937.15 RLN90823.1 - 0.065 13.1 0.0 0.23 11.3 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF 659) SIM_C PF06621.12 RLN90823.1 - 0.26 11.3 3.0 0.42 10.6 3.0 1.3 1 0 0 1 1 1 0 Single-minded protein C-terminus UCH PF00443.29 RLN90824.1 - 1.7e-57 194.9 0.0 2.5e-57 194.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN90824.1 - 1.2e-23 84.3 0.0 3.1e-23 82.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Polysacc_deac_1 PF01522.21 RLN90825.1 - 1.4e-09 37.9 0.0 2.1e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF983 PF06170.12 RLN90825.1 - 2 8.9 6.1 2.8 8.4 2.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF983) Cofilin_ADF PF00241.20 RLN90826.1 - 4.4e-32 110.4 0.1 7.9e-32 109.6 0.1 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Arm PF00514.23 RLN90826.1 - 1.1e-08 34.8 53.0 0.0014 18.6 0.2 12.1 13 0 0 13 13 13 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN90826.1 - 2.2e-07 30.5 43.1 0.0056 16.8 0.1 11.1 10 0 0 10 10 9 3 HEAT repeat Cnd1 PF12717.7 RLN90826.1 - 4.7e-07 30.0 1.8 0.45 10.5 0.0 5.2 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 KAP PF05804.12 RLN90826.1 - 2.4e-05 22.7 0.0 0.19 9.8 0.0 4.4 4 1 1 5 5 5 1 Kinesin-associated protein (KAP) HEAT_2 PF13646.6 RLN90826.1 - 3.5e-05 24.1 36.6 3.9e-05 23.9 1.8 8.1 5 2 1 7 7 7 3 HEAT repeats Proteasom_PSMB PF10508.9 RLN90826.1 - 0.0067 15.0 0.1 4.3 5.7 0.0 4.1 4 0 0 4 4 4 1 Proteasome non-ATPase 26S subunit UNC45-central PF11701.8 RLN90826.1 - 0.04 13.9 17.1 4 7.4 0.3 6.6 8 0 0 8 8 8 0 Myosin-binding striated muscle assembly central V-ATPase_H_N PF03224.14 RLN90826.1 - 0.057 12.7 5.8 1.9 7.7 0.1 4.1 4 1 0 4 4 4 0 V-ATPase subunit H RICTOR_N PF14664.6 RLN90826.1 - 0.1 11.6 6.3 0.042 12.8 1.2 3.0 3 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term Arm_2 PF04826.13 RLN90826.1 - 0.11 11.9 0.1 4 6.8 0.0 3.0 2 0 0 2 2 2 0 Armadillo-like Vac14_Fab1_bd PF12755.7 RLN90826.1 - 0.14 12.8 0.0 21 5.8 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HTH_31 PF13560.6 RLN90826.1 - 0.73 10.2 8.1 1.9 8.9 0.1 4.1 3 0 0 3 3 3 0 Helix-turn-helix domain zf-GRF PF06839.12 RLN90827.1 - 2.4e-12 46.8 2.1 4e-12 46.0 2.1 1.4 1 0 0 1 1 1 1 GRF zinc finger DEAD PF00270.29 RLN90827.1 - 0.0006 19.6 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Cadherin_C PF01049.17 RLN90827.1 - 0.0085 16.4 0.8 0.023 15.1 0.8 1.8 1 0 0 1 1 1 1 Cadherin cytoplasmic region ADK PF00406.22 RLN90828.1 - 2.6e-17 63.3 0.1 4.3e-17 62.6 0.1 1.4 1 0 0 1 1 1 1 Adenylate kinase HD_3 PF13023.6 RLN90828.1 - 2.1e-13 50.5 0.2 3.3e-13 49.9 0.2 1.3 1 0 0 1 1 1 1 HD domain AAA_17 PF13207.6 RLN90828.1 - 3.8e-09 37.1 0.5 1e-08 35.7 0.1 1.9 2 0 0 2 2 2 1 AAA domain DUF2252 PF10009.9 RLN90828.1 - 0.025 13.7 0.1 0.031 13.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) cNMP_binding PF00027.29 RLN90829.1 - 3.2e-11 43.2 0.0 6.3e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain FlbT PF07378.11 RLN90829.1 - 0.031 14.4 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Flagellar protein FlbT TMF_TATA_bd PF12325.8 RLN90830.1 - 0.04 14.1 0.7 0.04 14.1 0.7 4.6 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding T2SSM_b PF10741.9 RLN90830.1 - 0.053 13.3 0.4 0.053 13.3 0.4 3.1 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b DUF2458 PF10454.9 RLN90830.1 - 1.2 8.8 19.2 0.14 11.8 7.1 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2458) MRPL52 PF18699.1 RLN90830.1 - 1.6 9.0 14.8 8.6 6.6 0.5 4.4 4 0 0 4 4 4 0 Mitoribosomal protein mL52 ALMT PF11744.8 RLN90830.1 - 7.8 5.2 11.8 16 4.2 11.8 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter Thioredoxin PF00085.20 RLN90831.1 - 5.6e-28 96.9 0.0 1.1e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 RLN90831.1 - 7.1e-06 26.4 0.1 0.00014 22.3 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 RLN90831.1 - 0.00026 20.4 0.0 0.00057 19.3 0.0 1.8 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 RLN90831.1 - 0.00051 19.9 0.0 0.0008 19.3 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 RLN90831.1 - 0.0057 16.7 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.6 RLN90831.1 - 0.011 15.5 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.6 RLN90831.1 - 0.011 16.0 0.0 0.51 10.7 0.0 2.7 1 1 2 3 3 3 0 Thioredoxin-like Thioredoxin_6 PF13848.6 RLN90831.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 RLN90831.1 - 0.032 14.4 0.0 0.087 13.0 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like Glutaredoxin PF00462.24 RLN90831.1 - 0.1 12.8 1.1 0.18 12.1 0.1 2.1 2 1 0 2 2 2 0 Glutaredoxin DUF836 PF05768.14 RLN90831.1 - 0.11 12.9 0.1 0.24 11.8 0.0 1.6 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) YTH PF04146.15 RLN90832.1 - 6.3e-18 65.3 0.6 3e-17 63.0 0.6 1.9 1 1 0 1 1 1 1 YT521-B-like domain Cellulase PF00150.18 RLN90836.1 - 1.4e-23 83.7 5.9 2e-23 83.3 5.9 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2207 PF09972.9 RLN90837.1 - 1.7e-06 27.1 5.8 0.007 15.2 0.8 3.2 3 0 0 3 3 3 3 Predicted membrane protein (DUF2207) Prominin PF05478.11 RLN90837.1 - 1.5e-05 23.2 13.9 0.00021 19.4 0.2 3.9 3 1 1 4 4 4 2 Prominin Tweety PF04906.13 RLN90837.1 - 6e-05 21.9 14.0 0.0052 15.5 0.9 3.5 3 1 0 3 3 3 2 Tweety DUF1664 PF07889.12 RLN90837.1 - 0.0041 17.2 1.1 3.9 7.5 0.2 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF1664) SUR7 PF06687.12 RLN90837.1 - 0.0079 15.9 14.4 0.18 11.4 3.7 3.2 4 0 0 4 4 4 2 SUR7/PalI family Baculo_PEP_C PF04513.12 RLN90837.1 - 0.013 15.6 5.4 0.87 9.6 0.5 3.4 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 RLN90837.1 - 0.051 13.7 5.8 0.24 11.5 1.6 3.1 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 RLN90837.1 - 0.072 13.0 0.6 5.3 6.9 0.0 2.8 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain AATF-Che1 PF13339.6 RLN90837.1 - 0.11 13.2 0.1 0.36 11.5 0.0 1.9 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF148 PF02520.17 RLN90837.1 - 0.17 12.0 2.4 4.7 7.3 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function DUF148 TMEM43 PF07787.12 RLN90837.1 - 0.85 9.0 6.2 0.39 10.1 1.0 2.6 3 0 0 3 3 3 0 Transmembrane protein 43 ETRAMP PF09716.10 RLN90837.1 - 3.6 7.7 9.7 6 7.0 1.0 4.5 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Cellulase PF00150.18 RLN90838.1 - 2.2e-22 79.8 2.4 2.8e-22 79.4 2.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 RLN90839.1 - 1.4e-25 90.3 7.8 1.8e-25 90.0 7.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) E1_dh PF00676.20 RLN90840.1 - 1.6e-54 184.9 0.0 2.2e-54 184.4 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 RLN90840.1 - 1.3e-19 69.4 1.0 2.9e-19 68.3 1.0 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Transket_pyr PF02779.24 RLN90840.1 - 1.3e-10 41.3 0.0 2.4e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain R2K_2 PF18299.1 RLN90840.1 - 0.00048 20.0 0.1 0.0015 18.4 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain, R2K clade family 2 Presenilin PF01080.17 RLN90841.1 - 8.4e-117 390.3 5.9 2.2e-80 270.4 0.2 2.4 3 0 0 3 3 3 2 Presenilin SPX PF03105.19 RLN90841.1 - 0.0025 17.8 4.0 0.0025 17.8 4.0 2.1 2 0 0 2 2 2 1 SPX domain CDC45 PF02724.14 RLN90841.1 - 0.15 10.3 2.0 0.22 9.8 2.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Orthopox_F8 PF05886.11 RLN90841.1 - 0.21 11.7 0.1 0.21 11.7 0.1 3.6 3 1 0 3 3 1 0 Orthopoxvirus F8 protein Peptidase_S64 PF08192.11 RLN90841.1 - 0.23 9.9 2.9 0.4 9.1 2.9 1.3 1 0 0 1 1 1 0 Peptidase family S64 Apt1 PF10351.9 RLN90841.1 - 0.69 8.7 7.9 0.2 10.4 4.9 1.6 2 0 0 2 2 2 0 Golgi-body localisation protein domain Hid1 PF12722.7 RLN90841.1 - 0.71 7.9 2.8 1.1 7.4 2.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Plasmodium_Vir PF05795.11 RLN90841.1 - 0.8 9.1 5.4 1.8 7.9 2.3 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein PRP3 PF08572.10 RLN90841.1 - 1.2 8.9 15.2 0.2 11.4 1.1 2.2 2 0 0 2 2 2 0 pre-mRNA processing factor 3 (PRP3) GREB1 PF15782.5 RLN90841.1 - 1.3 6.0 7.6 1.8 5.6 7.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Androgen_recep PF02166.16 RLN90841.1 - 2.7 6.8 19.3 5.2 5.8 19.3 1.4 1 0 0 1 1 1 0 Androgen receptor DUF4231 PF14015.6 RLN90841.1 - 7 7.2 6.4 9.8 6.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) TERB2 PF15101.6 RLN90841.1 - 8.3 6.4 10.1 18 5.3 10.1 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Roughex PF06020.11 RLN90841.1 - 8.4 5.4 9.2 18 4.3 9.2 1.5 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 RLN90841.1 - 8.5 5.9 21.1 19 4.8 21.1 1.5 1 0 0 1 1 1 0 Spt20 family EF-hand_6 PF13405.6 RLN90843.1 - 4e-05 23.2 0.1 0.00015 21.4 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 RLN90843.1 - 0.0022 17.4 0.1 0.0051 16.3 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 RLN90843.1 - 0.0045 17.4 0.1 0.014 15.9 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN90843.1 - 0.01 15.3 0.1 0.03 13.8 0.1 1.8 1 0 0 1 1 1 0 EF hand WW PF00397.26 RLN90844.1 - 0.0035 17.4 0.6 0.0073 16.4 0.6 1.6 1 0 0 1 1 1 1 WW domain Mid1 PF12929.7 RLN90846.1 - 6.9e-17 61.8 10.3 1.1e-16 61.1 10.3 1.2 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 RLN90846.1 - 0.0094 16.6 10.9 0.18 12.4 1.4 2.7 1 1 1 2 2 2 2 Fz domain IFT46_B_C PF12317.8 RLN90847.1 - 1.2e-53 182.0 0.0 1.8e-53 181.4 0.0 1.2 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal fn3 PF00041.21 RLN90850.1 - 5.7e-08 33.0 4.5 0.25 11.7 0.0 5.3 5 0 0 5 5 5 3 Fibronectin type III domain POTRA_1 PF08478.10 RLN90850.1 - 0.058 13.7 0.1 36 4.8 0.0 4.4 4 0 0 4 4 4 0 POTRA domain, FtsQ-type DUF1661 PF07877.11 RLN90851.1 - 0.055 13.2 0.2 0.42 10.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1661) MRP-S23 PF10484.9 RLN90851.1 - 0.063 13.5 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S23 Nup54 PF13874.6 RLN90853.1 - 6.6e-29 100.8 0.2 1.2e-28 100.0 0.2 1.3 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Nucleoporin_FG2 PF15967.5 RLN90853.1 - 0.0036 15.9 24.0 0.0036 15.9 24.0 3.1 1 1 2 3 3 3 2 Nucleoporin FG repeated region Fib_alpha PF08702.10 RLN90853.1 - 0.14 12.4 0.4 0.19 11.9 0.4 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Nucleoporin_FG PF13634.6 RLN90853.1 - 0.29 12.0 86.0 1.4 9.8 37.8 3.5 1 1 2 3 3 3 0 Nucleoporin FG repeat region WD40 PF00400.32 RLN90855.1 - 2.2e-07 31.4 2.5 2.9 8.9 0.0 5.0 4 1 0 4 4 4 3 WD domain, G-beta repeat SGL PF08450.12 RLN90855.1 - 0.13 11.9 0.1 17 4.9 0.1 2.6 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region MCD PF05292.11 RLN90856.1 - 2.1e-82 276.6 0.1 5.4e-82 275.2 0.1 1.7 1 1 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain MCD_N PF17408.2 RLN90856.1 - 1.2e-09 38.2 0.2 6.5e-09 35.8 0.2 2.3 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase N-terminal domain EF-hand_1 PF00036.32 RLN90856.1 - 6.8e-08 31.5 3.7 1.4e-06 27.4 0.7 3.0 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 RLN90856.1 - 5e-06 26.3 1.5 0.013 15.3 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 RLN90856.1 - 1.5e-05 25.4 0.2 0.00028 21.3 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN90856.1 - 0.00011 21.8 1.2 0.0034 17.2 0.1 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 RLN90856.1 - 0.00036 19.9 0.8 0.0018 17.7 0.7 2.2 2 0 0 2 2 2 1 EF hand SIX1_SD PF16878.5 RLN90856.1 - 0.13 12.8 0.0 0.39 11.2 0.0 1.9 1 0 0 1 1 1 0 Transcriptional regulator, SIX1, N-terminal SD domain DUF1279 PF06916.13 RLN90857.1 - 8.8e-24 83.9 0.4 1.2e-23 83.5 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) PMD PF10536.9 RLN90857.1 - 0.14 11.3 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Plant mobile domain Gtr1_RagA PF04670.12 RLN90858.1 - 2.8e-160 530.8 0.2 4.6e-80 268.3 0.1 3.4 2 2 0 2 2 2 2 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 RLN90858.1 - 3.8e-05 23.7 0.9 0.77 9.6 0.0 4.2 4 0 0 4 4 4 1 RsgA GTPase Roc PF08477.13 RLN90858.1 - 0.0011 19.2 9.9 9.6 6.4 0.1 6.7 6 2 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase UBA_4 PF14555.6 RLN90858.1 - 0.0051 16.6 0.2 5.3 7.0 0.0 2.7 2 0 0 2 2 2 2 UBA-like domain ABC_tran PF00005.27 RLN90858.1 - 0.0062 17.1 1.9 0.62 10.6 0.1 3.0 2 0 0 2 2 2 1 ABC transporter PduV-EutP PF10662.9 RLN90858.1 - 0.015 15.0 0.5 0.27 11.0 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF4922 PF16269.5 RLN90858.1 - 0.028 14.2 0.5 9.9 5.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4922) NACHT PF05729.12 RLN90858.1 - 0.034 14.1 0.0 3.1 7.7 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Calsequestrin PF01216.17 RLN90858.1 - 0.036 13.1 2.5 3.8 6.4 0.2 2.2 2 0 0 2 2 2 0 Calsequestrin Mga PF05043.13 RLN90858.1 - 0.037 14.6 0.3 19 5.9 0.0 2.7 2 0 0 2 2 2 0 Mga helix-turn-helix domain AAA_7 PF12775.7 RLN90858.1 - 0.048 13.2 0.7 0.14 11.7 0.1 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 RLN90858.1 - 0.052 13.3 0.9 0.42 10.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 RLN90858.1 - 0.055 13.2 0.0 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain MMR_HSR1_Xtn PF16897.5 RLN90858.1 - 0.069 13.2 0.9 20 5.2 0.0 2.9 3 0 0 3 3 2 0 C-terminal region of MMR_HSR1 domain CRISPR_Cas9_WED PF18061.1 RLN90858.1 - 0.082 13.0 0.2 19 5.3 0.0 2.4 2 0 0 2 2 2 0 CRISPR-Cas9 WED domain TsaE PF02367.17 RLN90858.1 - 0.088 12.8 0.2 2 8.4 0.0 3.0 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Med29 PF11568.8 RLN90858.1 - 0.18 12.0 1.7 21 5.3 0.1 2.7 2 0 0 2 2 2 0 Mediator complex subunit 29 DUF4350 PF14258.6 RLN90858.1 - 0.2 12.1 0.0 41 4.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) Arf PF00025.21 RLN90858.1 - 0.46 9.9 6.9 24 4.3 0.4 4.5 3 2 0 3 3 3 0 ADP-ribosylation factor family AAA_29 PF13555.6 RLN90858.1 - 1.1 9.0 6.0 0.83 9.4 0.2 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Arm PF00514.23 RLN90859.1 - 5e-06 26.4 11.3 0.61 10.2 0.0 6.9 7 1 0 7 7 7 2 Armadillo/beta-catenin-like repeat IQ PF00612.27 RLN90859.1 - 0.0037 16.9 0.4 0.0097 15.6 0.4 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif FAA_hydrolase PF01557.18 RLN90860.1 - 2.1e-51 174.7 0.1 3.7e-30 105.2 0.0 2.1 2 0 0 2 2 2 2 Fumarylacetoacetate (FAA) hydrolase family Pkinase PF00069.25 RLN90860.1 - 5.9e-44 150.4 0.0 6.1e-27 94.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90860.1 - 3.5e-31 108.4 0.0 1.4e-17 63.9 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase GMP_synt_C PF00958.22 RLN90861.1 - 2e-44 149.6 0.0 4.3e-44 148.5 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 RLN90861.1 - 9.3e-31 107.1 0.0 1.3e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 RLN90861.1 - 1.1e-09 37.8 0.0 1.7e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 RLN90861.1 - 2.4e-06 27.5 0.0 5.7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 RLN90861.1 - 0.00012 21.1 0.0 0.00027 19.9 0.0 1.6 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 RLN90861.1 - 0.00013 21.6 0.0 0.00046 19.8 0.0 1.8 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 RLN90861.1 - 0.0003 20.9 0.0 0.00077 19.5 0.0 1.7 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family QueC PF06508.13 RLN90861.1 - 0.00094 18.7 0.0 0.027 14.0 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 RLN90861.1 - 0.022 14.1 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.20 RLN90861.1 - 0.1 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 PP-loop family Asn_synthase PF00733.21 RLN90861.1 - 0.19 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase ABC2_membrane PF01061.24 RLN90862.1 - 6.3e-37 127.0 25.1 6.3e-37 127.0 25.1 1.4 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN90862.1 - 9.4e-28 97.4 0.0 5.3e-16 59.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 RLN90862.1 - 2.5e-07 30.3 3.4 0.0082 15.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN90862.1 - 9.7e-07 28.8 1.3 0.024 14.5 0.3 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 RLN90862.1 - 2.5e-05 24.6 0.0 0.18 12.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 RLN90862.1 - 7.6e-05 23.2 3.3 0.04 14.3 0.2 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 RLN90862.1 - 9.6e-05 23.0 0.7 0.089 13.3 0.4 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 RLN90862.1 - 0.00014 21.5 0.1 0.058 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 RLN90862.1 - 0.001 19.2 4.5 0.44 10.6 0.1 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_21 PF13304.6 RLN90862.1 - 0.0011 18.8 0.1 1.3 8.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 RLN90862.1 - 0.0024 17.2 0.9 0.5 9.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin SMC_N PF02463.19 RLN90862.1 - 0.009 15.5 0.4 5.7 6.3 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 RLN90862.1 - 0.0094 15.6 0.3 0.23 11.0 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 RLN90862.1 - 0.019 15.1 0.6 5.7 7.0 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 RLN90862.1 - 0.021 14.7 3.1 3.3 7.6 0.2 2.7 2 0 0 2 2 2 0 NACHT domain G-alpha PF00503.20 RLN90862.1 - 0.021 14.0 0.1 0.057 12.6 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit Roc PF08477.13 RLN90862.1 - 0.047 13.9 0.3 14 5.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 RLN90862.1 - 0.051 13.3 1.4 2.2 7.9 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RLN90862.1 - 0.058 13.9 0.0 19 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RLN90862.1 - 0.07 13.5 0.6 8.4 6.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase PduV-EutP PF10662.9 RLN90862.1 - 0.071 12.9 2.2 1.9 8.2 0.4 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 RLN90862.1 - 0.1 12.6 0.6 1.9 8.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 RLN90862.1 - 0.11 11.7 0.8 0.2 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 RLN90862.1 - 0.15 12.1 1.2 1.5 8.8 0.3 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 RLN90862.1 - 0.19 11.5 0.1 17 5.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RLN90862.1 - 0.19 11.2 1.4 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_10 PF12846.7 RLN90862.1 - 0.26 10.1 0.8 2.3 7.1 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain DUF4227 PF14004.6 RLN90862.1 - 0.45 10.5 4.6 0.65 10.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4227) ATPase PF06745.13 RLN90862.1 - 0.64 9.3 1.8 9.1 5.6 0.1 2.3 2 0 0 2 2 2 0 KaiC ABC2_membrane_3 PF12698.7 RLN90862.1 - 1.9 7.5 24.0 8.1 5.4 24.0 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane PF01061.24 RLN90863.1 - 6.7e-33 113.9 34.5 6.7e-33 113.9 34.5 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 RLN90863.1 - 0.00011 21.4 14.4 0.00011 21.4 14.4 1.9 1 1 1 2 2 2 1 ABC-2 family transporter protein PDR_CDR PF06422.12 RLN90863.1 - 0.0063 16.4 0.0 0.0063 16.4 0.0 3.0 3 1 1 4 4 4 1 CDR ABC transporter Ninjurin PF04923.12 RLN90863.1 - 0.0095 15.9 1.1 0.089 12.7 0.0 2.7 2 1 0 2 2 2 1 Ninjurin SEN1_N PF12726.7 RLN90864.1 - 0.17 10.1 0.0 0.18 10.0 0.0 1.0 1 0 0 1 1 1 0 SEN1 N terminal zf-C2H2 PF00096.26 RLN90865.1 - 9.9e-16 57.2 24.1 5.1e-06 26.7 1.1 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RLN90865.1 - 7.5e-15 54.6 20.4 8.4e-07 29.1 0.1 4.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 RLN90865.1 - 1.2e-09 38.1 22.9 0.0039 17.9 1.1 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 RLN90865.1 - 1.5e-05 25.2 6.7 0.04 14.2 0.8 2.7 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 RLN90865.1 - 0.00024 20.8 10.5 0.29 10.9 0.1 3.9 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 RLN90865.1 - 0.0011 18.7 11.7 0.18 11.6 0.7 3.5 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 RLN90865.1 - 0.0061 16.8 0.1 6 7.3 0.0 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 RLN90865.1 - 0.11 13.0 3.0 6.4 7.3 0.2 2.9 3 0 0 3 3 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 RLN90865.1 - 0.18 11.8 7.8 1.4 9.0 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 RLN90865.1 - 0.26 11.4 6.4 3.7 7.6 0.8 2.8 2 1 1 3 3 3 0 Aberrant zinc-finger Vanabin-2 PF11437.8 RLN90865.1 - 3 8.1 5.4 3 8.1 0.2 2.6 1 1 2 3 3 3 0 Vanadium-binding protein 2 HSF_DNA-bind PF00447.17 RLN90866.1 - 7.7e-21 74.5 1.8 1.1e-20 74.0 1.8 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding TP2 PF01254.18 RLN90866.1 - 0.26 11.9 2.5 0.17 12.5 0.8 1.6 2 0 0 2 2 2 0 Nuclear transition protein 2 Glyco_hydro_3 PF00933.21 RLN90867.1 - 1.4e-52 179.0 0.0 1.8e-52 178.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN90867.1 - 1.4e-17 64.4 0.0 2.8e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain SBP_bac_3 PF00497.20 RLN90867.1 - 0.055 12.9 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Pyr_redox_2 PF07992.14 RLN90868.1 - 2.6e-35 122.1 0.4 3.2e-35 121.8 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RLN90868.1 - 2e-13 50.7 1.1 4.3e-09 36.8 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RLN90868.1 - 7.7e-09 35.6 1.5 0.0073 15.9 0.2 3.6 2 2 2 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 RLN90868.1 - 3.1e-08 33.2 0.1 3.7e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 RLN90868.1 - 1.6e-07 30.9 0.1 0.00034 20.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RLN90868.1 - 2.4e-07 30.9 0.7 0.089 13.0 0.1 3.3 2 1 0 3 3 3 2 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 RLN90868.1 - 3.3e-07 29.7 0.1 0.00057 19.1 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 RLN90868.1 - 0.00015 20.7 1.7 0.14 10.8 0.1 2.9 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.17 RLN90868.1 - 0.00017 20.9 0.6 0.28 10.4 0.1 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.6 RLN90868.1 - 0.00028 20.9 2.7 0.39 10.7 0.0 3.7 3 1 1 4 4 4 2 FAD-NAD(P)-binding TrkA_N PF02254.18 RLN90868.1 - 0.00046 20.4 0.5 0.4 10.9 0.0 2.7 2 1 0 2 2 2 2 TrkA-N domain Trp_halogenase PF04820.14 RLN90868.1 - 0.0017 17.3 3.6 0.034 13.0 0.1 3.0 3 1 0 3 3 3 1 Tryptophan halogenase GMC_oxred_N PF00732.19 RLN90868.1 - 0.0063 15.9 0.0 2 7.7 0.0 2.6 3 0 0 3 3 3 1 GMC oxidoreductase AlaDh_PNT_C PF01262.21 RLN90868.1 - 0.015 14.6 0.2 2.4 7.4 0.2 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Tubulin PF00091.25 RLN90868.1 - 0.036 14.3 0.3 0.17 12.1 0.3 1.9 1 1 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Malic_M PF03949.15 RLN90868.1 - 0.038 13.3 0.8 5 6.3 0.0 2.5 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain NAD_binding_7 PF13241.6 RLN90868.1 - 0.05 14.0 0.1 5.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 RLN90868.1 - 0.076 12.3 0.7 8.3 5.5 0.1 2.9 3 0 0 3 3 3 0 FAD binding domain ApbA PF02558.16 RLN90868.1 - 0.092 12.4 0.1 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 RLN90868.1 - 0.26 10.6 0.1 0.26 10.6 0.1 2.0 2 0 0 2 2 2 0 ThiF family GIDA PF01134.22 RLN90868.1 - 0.88 8.6 9.5 0.89 8.6 0.3 3.0 2 1 1 3 3 3 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 RLN90868.1 - 1.2 8.1 6.6 1.6 7.7 1.4 2.5 2 1 1 3 3 3 0 FAD binding domain Pyr_redox_2 PF07992.14 RLN90869.1 - 3.2e-39 134.9 0.6 3.8e-39 134.7 0.6 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RLN90869.1 - 3.7e-13 49.8 0.7 9.2e-09 35.7 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RLN90869.1 - 6.6e-10 38.7 0.1 0.0004 19.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RLN90869.1 - 4.3e-09 36.4 0.6 0.0017 18.0 0.1 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 RLN90869.1 - 2.4e-08 33.5 0.1 0.00077 18.6 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 RLN90869.1 - 1.6e-07 31.4 0.3 0.0019 18.4 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 RLN90869.1 - 6e-07 28.9 0.5 1.6e-05 24.3 0.1 2.4 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 RLN90869.1 - 2.4e-06 26.7 1.8 0.00016 20.6 0.0 3.0 3 0 0 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.14 RLN90869.1 - 4.2e-06 25.7 1.4 0.002 16.9 0.0 2.7 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_9 PF13454.6 RLN90869.1 - 9.4e-06 25.7 1.5 0.0047 16.9 0.0 3.6 3 1 1 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.17 RLN90869.1 - 0.00022 20.5 0.4 0.11 11.7 0.0 2.2 2 0 0 2 2 2 2 Thi4 family AlaDh_PNT_C PF01262.21 RLN90869.1 - 0.00073 18.9 0.2 0.76 9.0 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 RLN90869.1 - 0.0012 19.1 0.2 0.88 9.8 0.0 3.2 3 0 0 3 3 3 1 TrkA-N domain GIDA PF01134.22 RLN90869.1 - 0.0026 16.9 3.6 0.37 9.8 1.1 2.7 2 1 1 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 RLN90869.1 - 0.031 13.5 3.6 0.084 12.1 0.0 3.0 4 0 0 4 4 4 0 FAD binding domain GMC_oxred_N PF00732.19 RLN90869.1 - 0.037 13.4 0.0 3.9 6.7 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Malic_M PF03949.15 RLN90869.1 - 0.085 12.1 0.8 1.8 7.7 0.2 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain FAD_binding_2 PF00890.24 RLN90869.1 - 0.13 11.3 3.5 0.33 10.0 0.2 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 RLN90869.1 - 0.21 12.0 1.0 6.3 7.3 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_oxidored PF12831.7 RLN90869.1 - 0.28 10.5 1.7 0.8 9.0 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase ThiF PF00899.21 RLN90869.1 - 0.34 10.2 1.9 0.44 9.9 0.2 2.0 2 0 0 2 2 2 0 ThiF family Pyr_redox_2 PF07992.14 RLN90870.1 - 1.2e-40 139.6 0.1 1.5e-40 139.3 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RLN90870.1 - 7.2e-13 48.9 1.6 1.8e-09 38.0 0.6 2.6 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RLN90870.1 - 9.4e-10 38.2 0.1 1.1e-05 24.8 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RLN90870.1 - 2.7e-07 30.5 2.1 0.0064 16.1 0.0 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 RLN90870.1 - 1.1e-06 27.8 1.5 0.0051 15.7 0.0 3.1 3 0 0 3 3 3 2 Tryptophan halogenase K_oxygenase PF13434.6 RLN90870.1 - 1.9e-06 27.3 0.1 3.2e-05 23.2 0.1 2.0 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 RLN90870.1 - 2.1e-06 27.1 0.0 0.0072 15.4 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 RLN90870.1 - 6.3e-06 26.3 0.6 0.0023 17.9 0.0 3.3 2 2 1 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 RLN90870.1 - 9.5e-06 25.8 0.3 0.058 13.6 0.0 3.0 2 1 1 3 3 3 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 RLN90870.1 - 0.00018 20.8 0.4 0.38 10.0 0.0 2.3 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 RLN90870.1 - 0.00038 19.3 0.5 0.18 10.5 0.0 2.5 2 0 0 2 2 2 2 HI0933-like protein TrkA_N PF02254.18 RLN90870.1 - 0.0017 18.6 0.4 0.5 10.6 0.3 2.5 2 0 0 2 2 2 1 TrkA-N domain FAD_binding_3 PF01494.19 RLN90870.1 - 0.0066 15.7 2.3 0.025 13.8 0.0 2.4 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.6 RLN90870.1 - 0.05 14.1 0.1 13 6.3 0.1 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_oxidored PF12831.7 RLN90870.1 - 0.11 11.9 0.2 10 5.3 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 RLN90870.1 - 0.14 11.2 1.0 2.1 7.3 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 RLN90870.1 - 0.15 12.3 0.9 8.5 6.7 0.4 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Apo-CIII PF05778.12 RLN90871.1 - 0.00047 19.7 0.8 5.7 6.6 0.1 3.6 3 0 0 3 3 3 2 Apolipoprotein CIII (Apo-CIII) Fumarate_red_C PF02300.17 RLN90871.1 - 0.018 15.1 1.7 43 4.2 0.0 4.0 4 0 0 4 4 4 0 Fumarate reductase subunit C SH3_7 PF12914.7 RLN90871.1 - 0.057 13.6 7.3 24 5.2 0.1 4.2 3 0 0 3 3 3 0 SH3 domain of SH3b2 type TACI-CRD2 PF09305.10 RLN90871.1 - 0.26 11.3 1.9 94 3.1 0.1 3.4 3 0 0 3 3 3 0 TACI, cysteine-rich domain THF_DHG_CYH_C PF02882.19 RLN90872.1 - 5.3e-62 207.9 0.2 7.3e-62 207.4 0.2 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 RLN90872.1 - 1.5e-33 115.5 0.0 2.6e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF43 PF01861.16 RLN90872.1 - 0.14 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain PX PF00787.24 RLN90873.1 - 3.6e-10 39.8 0.4 7.6e-10 38.8 0.4 1.6 1 0 0 1 1 1 1 PX domain Kelch_3 PF13415.6 RLN90874.1 - 1.4e-14 53.9 3.1 8.4e-06 25.9 0.1 5.7 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.6 RLN90874.1 - 1.1e-12 47.7 0.0 8.9e-06 25.6 0.0 5.4 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN90874.1 - 3.3e-11 42.9 0.0 0.0094 15.9 0.0 5.9 6 1 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 RLN90874.1 - 1.5e-07 31.4 0.4 0.035 14.4 0.0 5.3 5 1 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 RLN90874.1 - 0.00026 20.5 6.9 0.033 13.8 0.0 4.6 5 1 0 5 5 5 2 Kelch motif LRR_9 PF14580.6 RLN90876.1 - 7.8e-38 129.7 1.8 6.2e-37 126.8 1.8 2.0 1 1 0 1 1 1 1 Leucine-rich repeat SAP PF02037.27 RLN90876.1 - 2.1e-12 46.5 2.3 4.1e-12 45.6 2.3 1.4 1 0 0 1 1 1 1 SAP domain LRR_8 PF13855.6 RLN90876.1 - 7.7e-08 32.0 0.6 3.2e-07 30.0 0.5 2.0 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 RLN90876.1 - 1.6e-05 25.1 0.5 0.026 15.0 0.1 2.9 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) TRAM_LAG1_CLN8 PF03798.16 RLN90876.1 - 0.00023 21.0 6.7 0.00039 20.2 6.7 1.3 1 0 0 1 1 1 1 TLC domain LRR_8 PF13855.6 RLN90877.1 - 1.6e-06 27.8 0.1 0.026 14.3 0.1 2.7 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RLN90877.1 - 0.12 12.8 1.0 7 7.2 0.1 3.2 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) His_Phos_1 PF00300.22 RLN90878.1 - 1.9e-24 86.4 0.0 1.8e-23 83.3 0.0 2.3 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF4855 PF16147.5 RLN90882.1 - 0.11 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4855) SMYLE_N PF18615.1 RLN90882.1 - 8.6 5.8 8.4 10 5.5 8.4 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Cauli_AT PF03233.13 RLN90883.1 - 0.059 13.3 1.0 0.69 9.8 0.0 2.6 1 1 1 2 2 2 0 Aphid transmission protein DUF659 PF04937.15 RLN90883.1 - 0.082 12.8 0.0 0.27 11.1 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF 659) AAA_22 PF13401.6 RLN90887.1 - 2.1e-11 44.3 0.0 6.4e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RLN90887.1 - 1e-09 39.0 1.4 9.6e-09 35.8 0.4 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 RLN90887.1 - 2.7e-05 24.6 0.0 0.0001 22.7 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 RLN90887.1 - 0.0018 17.7 0.0 0.0064 15.9 0.0 1.9 1 1 0 1 1 1 1 Bacterial TniB protein AAA_19 PF13245.6 RLN90887.1 - 0.0064 16.8 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RLN90887.1 - 0.019 15.1 0.0 0.054 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_lid_10 PF17872.1 RLN90887.1 - 0.023 14.8 0.0 0.062 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA lid domain AAA_5 PF07728.14 RLN90887.1 - 0.03 14.3 0.0 0.27 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 RLN90887.1 - 0.031 14.2 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain T2SSC PF11356.8 RLN90887.1 - 0.04 13.8 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 Type II secretion system protein C AAA_30 PF13604.6 RLN90887.1 - 0.047 13.4 0.0 0.52 10.0 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 RLN90887.1 - 0.06 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 RLN90887.1 - 0.067 13.0 0.5 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 RLN90887.1 - 0.099 12.4 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain WW_FCH_linker PF16623.5 RLN90887.1 - 0.12 13.1 0.9 0.69 10.7 0.0 2.8 3 0 0 3 3 2 0 Unstructured linker region between on GAS7 protein AAA_28 PF13521.6 RLN90887.1 - 0.14 12.4 0.3 0.93 9.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 RLN90887.1 - 0.15 12.6 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 RLN90887.1 - 0.16 12.3 0.0 0.49 10.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Peptidase_M48 PF01435.18 RLN90888.1 - 2.1e-10 40.7 0.0 3.2e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Phage_holin_5_2 PF16079.5 RLN90888.1 - 0.07 13.5 0.3 0.34 11.3 0.1 2.1 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V Leu_Phe_trans PF03588.14 RLN90889.1 - 6.7e-23 81.0 0.0 9.8e-23 80.5 0.0 1.2 1 0 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase DIRP PF06584.13 RLN90890.1 - 0.66 10.2 3.6 1.6 8.9 3.6 1.7 1 0 0 1 1 1 0 DIRP WD40 PF00400.32 RLN90891.1 - 7.3e-16 58.3 8.2 3.3e-06 27.7 0.1 6.1 5 1 0 5 5 5 5 WD domain, G-beta repeat UPF0176_N PF17773.1 RLN90893.1 - 7.8e-16 58.2 0.0 1.4e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 RLN90893.1 - 9.2e-10 39.0 0.0 1.6e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese_C PF12368.8 RLN90893.1 - 1.1e-05 25.7 1.5 2.1e-05 24.8 1.5 1.5 1 0 0 1 1 1 1 Rhodanase C-terminal DUF2430 PF10353.9 RLN90893.1 - 8e-05 23.0 0.0 0.00014 22.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2430) zinc_ribbon_9 PF14369.6 RLN90893.1 - 0.061 13.6 1.6 4.7 7.5 3.7 2.3 1 1 1 2 2 2 0 zinc-ribbon D-ser_dehydrat PF14031.6 RLN90894.1 - 4.5e-20 72.1 0.1 1.7e-19 70.2 0.0 2.0 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 RLN90894.1 - 7.7e-20 71.5 0.4 1.1e-19 71.0 0.4 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain EF-hand_14 PF17959.1 RLN90894.1 - 0.059 13.7 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain 2OG-FeII_Oxy_3 PF13640.6 RLN90895.1 - 2.7e-18 66.6 0.0 5.4e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 RLN90895.1 - 1.3e-09 38.6 0.0 4.6e-09 36.8 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 RLN90895.1 - 0.0036 17.6 0.0 0.0098 16.2 0.0 1.8 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Oxygenase-NA PF09859.9 RLN90895.1 - 0.02 14.4 0.5 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Oxygenase, catalysing oxidative methylation of damaged DNA RasGEF PF00617.19 RLN90896.1 - 3.9e-40 137.9 0.1 6.6e-40 137.2 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 RLN90896.1 - 2.9e-14 53.2 0.0 6.3e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif Methyltransf_15 PF09445.10 RLN90897.1 - 1.1e-34 119.4 0.0 1.5e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 RLN90897.1 - 5.3e-07 29.6 0.1 5.3e-07 29.6 0.1 1.5 2 0 0 2 2 2 1 Met-10+ like-protein UPF0020 PF01170.18 RLN90897.1 - 1.5e-06 28.1 0.2 1.3e-05 25.0 0.2 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 RLN90897.1 - 6.3e-06 26.0 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 RLN90897.1 - 3.8e-05 24.3 0.0 0.00015 22.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.17 RLN90897.1 - 0.00011 21.5 0.0 0.00021 20.5 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.6 RLN90897.1 - 0.00013 21.8 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN90897.1 - 0.00032 21.3 0.0 0.0015 19.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 RLN90897.1 - 0.00038 20.0 0.1 0.00082 18.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 RLN90897.1 - 0.0012 18.8 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 RLN90897.1 - 0.0052 16.1 0.0 0.0085 15.4 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase MethyltransfD12 PF02086.15 RLN90897.1 - 0.0066 16.2 0.0 0.031 13.9 0.0 1.9 1 1 1 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase MCR_C PF04609.12 RLN90897.1 - 0.069 12.2 0.3 1.1 8.3 0.1 2.1 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein C Sel1 PF08238.12 RLN90898.1 - 3.8e-39 132.2 25.9 4.4e-06 27.2 4.1 8.5 8 0 0 8 8 8 7 Sel1 repeat TPR_1 PF00515.28 RLN90898.1 - 0.081 12.8 10.1 15 5.6 0.0 5.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN90898.1 - 0.12 12.6 14.0 20 5.6 0.1 6.4 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN90898.1 - 2.3 9.3 7.2 11 7.1 0.1 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat FAD_binding_1 PF00667.20 RLN90899.1 - 3.3e-51 174.0 0.0 6e-51 173.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 RLN90899.1 - 3e-27 95.6 0.0 5.9e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 RLN90899.1 - 1.7e-13 51.2 0.0 3.4e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Atx10homo_assoc PF09759.9 RLN90900.1 - 1.2e-32 111.8 0.2 2e-31 108.0 0.0 2.7 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 RLN90900.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Armadillo-like Histone PF00125.24 RLN90901.1 - 6.1e-37 126.9 0.2 7.3e-37 126.7 0.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 RLN90901.1 - 0.00018 21.6 0.0 0.0002 21.5 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 RLN90901.1 - 0.00022 21.6 0.0 0.00027 21.2 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 RLN90901.1 - 0.046 13.8 0.0 0.053 13.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Death PF00531.22 RLN90901.1 - 0.049 13.8 0.0 0.063 13.5 0.0 1.2 1 0 0 1 1 1 0 Death domain CBFD_NFYB_HMF PF00808.23 RLN90901.1 - 0.088 13.1 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone UQ_con PF00179.26 RLN90902.1 - 3.8e-29 101.1 0.6 1.1e-22 80.1 0.7 2.0 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme LRR_8 PF13855.6 RLN90903.1 - 4.4e-49 164.1 37.4 9.5e-09 34.9 2.6 10.2 5 3 5 11 11 11 11 Leucine rich repeat LRR_4 PF12799.7 RLN90903.1 - 3.8e-40 135.2 23.1 8.5e-05 22.8 0.2 11.8 6 4 6 13 13 13 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN90903.1 - 2.6e-08 33.3 29.8 8.1 7.4 0.1 13.7 16 0 0 16 16 16 1 Leucine Rich Repeat LRR_9 PF14580.6 RLN90903.1 - 1.1e-07 31.5 14.5 0.064 12.8 0.6 5.8 3 3 2 5 5 5 4 Leucine-rich repeat LRR_6 PF13516.6 RLN90903.1 - 1.3e-07 31.1 25.3 0.2 11.8 0.1 12.2 14 0 0 14 14 14 2 Leucine Rich repeat RsmF_methylt_CI PF17126.5 RLN90903.1 - 0.0086 16.1 0.2 7.3 6.7 0.0 4.3 4 0 0 4 4 4 1 RsmF rRNA methyltransferase first C-terminal domain BRE1 PF08647.11 RLN90903.1 - 1.4 9.0 10.7 0.1 12.7 4.1 2.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase HAUS-augmin3 PF14932.6 RLN90903.1 - 8.2 5.9 12.1 24 4.4 12.1 1.8 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Pkinase PF00069.25 RLN90904.1 - 2.8e-55 187.5 0.0 4.2e-55 187.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90904.1 - 7.1e-37 127.1 0.0 1.1e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN90904.1 - 5.1e-08 32.6 0.0 1.4e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RLN90904.1 - 1.4e-06 27.4 0.0 2.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 RLN90904.1 - 0.02 14.2 0.4 0.051 12.9 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 RLN90904.1 - 0.14 11.2 0.1 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Cyclin PF08613.11 RLN90905.1 - 7.7e-15 55.6 0.0 7.7e-15 55.6 0.0 3.3 2 1 0 2 2 2 1 Cyclin WW PF00397.26 RLN90905.1 - 1.2e-08 34.9 2.0 1.2e-08 34.9 2.0 1.9 2 0 0 2 2 2 1 WW domain Cyclin_N PF00134.23 RLN90905.1 - 1.1e-06 28.4 0.1 2.2e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Glyco_hydro_12 PF01670.16 RLN90906.1 - 9.4e-42 143.4 8.7 9.4e-42 143.4 8.7 2.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 12 FtsJ PF01728.19 RLN90907.1 - 3.7e-08 33.7 0.0 6.8e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Rdx PF10262.9 RLN90908.1 - 0.012 15.8 0.0 0.047 13.9 0.0 2.1 1 0 0 1 1 1 0 Rdx family RRM_1 PF00076.22 RLN90909.1 - 1.8e-16 59.7 0.1 6e-06 26.0 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RLN90909.1 - 4.6e-05 23.2 0.0 0.019 14.8 0.0 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF4523 PF15023.6 RLN90909.1 - 0.00062 19.6 0.0 0.23 11.3 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF4523) HalX PF08663.10 RLN90909.1 - 0.002 18.4 2.0 8.1 6.8 0.3 3.6 3 0 0 3 3 3 1 HalX domain DUF1866 PF08952.11 RLN90909.1 - 0.0069 16.2 6.7 0.066 13.1 0.0 3.6 4 1 0 4 4 4 1 Domain of unknown function (DUF1866) HSF_DNA-bind PF00447.17 RLN90910.1 - 1.4e-28 99.4 0.0 2.3e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding ZapB PF06005.12 RLN90910.1 - 0.071 13.6 1.4 0.19 12.2 1.4 1.7 1 0 0 1 1 1 0 Cell division protein ZapB WD40_alt PF14077.6 RLN90910.1 - 0.13 12.1 0.8 0.27 11.1 0.3 1.7 2 0 0 2 2 2 0 Alternative WD40 repeat motif bZIP_1 PF00170.21 RLN90910.1 - 0.16 12.1 1.6 0.42 10.7 1.6 1.7 1 0 0 1 1 1 0 bZIP transcription factor DASH_Dam1 PF08653.10 RLN90910.1 - 0.22 11.4 0.1 0.44 10.4 0.1 1.5 1 0 0 1 1 1 0 DASH complex subunit Dam1 FYVE PF01363.21 RLN90913.1 - 4.7e-15 55.5 15.7 1e-14 54.4 15.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN90913.1 - 0.091 13.0 16.2 0.033 14.4 10.9 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger adh_short PF00106.25 RLN90914.1 - 5.8e-32 110.7 6.9 2.5e-20 72.8 0.1 2.5 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN90914.1 - 4.8e-17 62.3 7.9 3.6e-11 43.1 0.1 2.5 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN90914.1 - 4.7e-06 26.6 3.3 0.00018 21.4 2.3 2.2 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 RLN90914.1 - 3.7e-05 23.3 1.2 0.0029 17.1 1.2 2.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 RLN90914.1 - 0.022 14.6 1.5 0.032 14.1 1.5 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 RLN90914.1 - 0.058 13.0 0.2 0.091 12.4 0.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.13 RLN90914.1 - 0.11 12.0 2.2 3.7 7.0 2.0 2.2 2 1 0 2 2 2 0 NmrA-like family CCT PF06203.14 RLN90915.1 - 1e-17 63.9 8.8 1.8e-17 63.1 8.8 1.4 1 0 0 1 1 1 1 CCT motif RNase_T PF00929.24 RLN90917.1 - 1.8e-11 44.9 0.0 2.6e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Exonuclease zf-CCCH PF00642.24 RLN90917.1 - 4.5e-08 32.8 19.7 2.1e-06 27.5 1.4 3.3 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 RLN90917.1 - 4.8e-06 26.2 19.3 0.0005 19.8 2.1 3.1 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 RLN90917.1 - 0.00011 22.5 11.0 0.038 14.5 2.6 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger DNA_pol_A_exo1 PF01612.20 RLN90917.1 - 0.00027 20.7 0.1 0.0007 19.3 0.1 1.6 1 1 0 1 1 1 1 3'-5' exonuclease zf_CCCH_4 PF18345.1 RLN90917.1 - 0.0011 18.9 19.3 0.0063 16.5 1.4 3.2 3 1 0 3 3 3 2 Zinc finger domain Torus PF16131.5 RLN90917.1 - 0.013 16.2 9.9 0.16 12.7 0.4 3.6 4 1 1 5 5 5 0 Torus domain zf-CCCH_3 PF15663.5 RLN90917.1 - 0.053 13.7 2.7 1.4 9.2 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger containing family Complex1_LYR PF05347.15 RLN90918.1 - 4e-09 36.4 0.7 7.6e-09 35.5 0.1 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) SUIM_assoc PF16619.5 RLN90918.1 - 0.0035 17.4 4.5 0.017 15.2 5.3 1.7 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Complex1_LYR_2 PF13233.6 RLN90918.1 - 0.12 13.1 5.1 0.51 11.1 5.1 2.0 1 1 0 1 1 1 0 Complex1_LYR-like Transketolase_N PF00456.21 RLN90921.1 - 8.5e-83 278.1 0.5 5e-82 275.5 0.3 2.0 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 RLN90921.1 - 5.9e-40 136.8 0.1 9.8e-40 136.1 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 RLN90921.1 - 4.5e-09 36.3 0.0 1.2e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Adenyl_transf PF04439.12 RLN90921.1 - 0.035 13.2 0.1 0.12 11.5 0.1 1.7 2 0 0 2 2 2 0 Streptomycin adenylyltransferase DXP_synthase_N PF13292.6 RLN90921.1 - 0.05 12.8 0.0 0.086 12.0 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Mur_ligase_C PF02875.21 RLN90921.1 - 0.12 12.7 0.1 6.4 7.1 0.0 2.6 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain CYYR1 PF10873.8 RLN90921.1 - 2.3 8.7 3.7 3.4 8.1 0.5 2.1 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Phos_pyr_kin PF08543.12 RLN90922.1 - 1.1e-81 273.9 1.2 1.7e-52 178.3 0.8 2.2 2 0 0 2 2 2 2 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 RLN90922.1 - 4.2e-26 92.1 0.0 6.9e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 RLN90922.1 - 2.9e-06 26.8 0.1 8.6e-05 22.0 0.1 2.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.15 RLN90922.1 - 0.00054 19.4 1.5 0.03 13.7 0.1 2.4 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family RPN6_N PF18055.1 RLN90922.1 - 0.032 14.6 0.3 0.1 12.9 0.1 1.9 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain Myotub-related PF06602.14 RLN90923.1 - 5e-119 397.4 0.0 8.2e-119 396.6 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain C2 PF00168.30 RLN90923.1 - 4.5e-16 59.0 0.0 1.1e-15 57.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain Y_phosphatase3 PF13350.6 RLN90923.1 - 0.0034 17.4 0.0 0.0068 16.4 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 RLN90923.1 - 0.0068 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DCP1 PF06058.13 RLN90924.1 - 7.9e-17 61.3 0.0 1.2e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 RLN90924.1 - 1.2e-06 27.7 0.1 2.1e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus SPX PF03105.19 RLN90924.1 - 0.014 15.3 14.2 0.019 14.9 14.2 1.1 1 0 0 1 1 1 0 SPX domain PAT1 PF09770.9 RLN90924.1 - 0.028 12.7 16.5 0.031 12.6 16.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ORC6 PF05460.13 RLN90924.1 - 1.6 7.9 12.4 2.2 7.5 12.4 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) API5 PF05918.11 RLN90924.1 - 1.8 7.2 8.3 3.1 6.5 8.3 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Nucleo_P87 PF07267.11 RLN90924.1 - 5.2 5.8 9.2 6.9 5.4 9.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HIT PF01230.23 RLN90926.1 - 7.7e-25 87.5 0.0 9.6e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 RLN90926.1 - 3.4e-07 30.7 0.0 4.5e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding PhoLip_ATPase_C PF16212.5 RLN90927.1 - 9.6e-65 218.8 5.3 9.6e-65 218.8 5.3 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RLN90927.1 - 1.2e-20 72.9 0.4 2.7e-20 71.8 0.4 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RLN90927.1 - 6.4e-10 39.7 2.1 0.0025 18.1 1.9 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN90927.1 - 1.4e-08 34.7 0.0 5.4e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RLN90927.1 - 0.0051 16.4 0.0 0.015 14.8 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RLN90927.1 - 0.013 15.3 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 RLN90927.1 - 0.058 13.8 0.0 4.1 7.7 0.0 2.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase VHP PF02209.19 RLN90928.1 - 1.4e-15 57.1 0.1 2.7e-15 56.1 0.1 1.5 1 0 0 1 1 1 1 Villin headpiece domain Gelsolin PF00626.22 RLN90928.1 - 3.4e-12 46.1 0.0 5.8e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat SAP130_C PF16014.5 RLN90928.1 - 0.21 10.6 8.5 0.27 10.3 8.5 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus DEC-1_N PF04625.13 RLN90928.1 - 1.3 8.0 10.3 1.9 7.4 10.3 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region FAP PF07174.11 RLN90928.1 - 4.5 6.7 19.9 30 3.9 19.2 2.0 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) LRR_4 PF12799.7 RLN90930.1 - 1.6e-19 69.7 15.2 5.4e-07 29.8 0.4 4.8 4 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN90930.1 - 1.9e-19 69.2 15.2 6.4e-06 25.8 0.9 4.5 3 1 0 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 RLN90930.1 - 4.6e-07 29.5 23.9 0.011 15.2 0.7 4.9 3 2 2 5 5 5 4 Leucine-rich repeat LRR_6 PF13516.6 RLN90930.1 - 7.2e-06 25.6 13.9 0.16 12.1 0.1 6.6 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 RLN90930.1 - 0.00037 20.7 5.8 25 5.9 0.1 5.8 6 0 0 6 6 6 2 Leucine Rich Repeat Utp14 PF04615.13 RLN90930.1 - 0.064 11.8 61.4 0.11 11.1 61.4 1.2 1 0 0 1 1 1 0 Utp14 protein LRR_8 PF13855.6 RLN90932.1 - 7.5e-24 83.3 31.8 1.6e-09 37.4 1.5 4.9 2 1 4 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 RLN90932.1 - 5.5e-20 71.1 15.2 2.2e-05 24.7 0.0 5.7 2 1 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN90932.1 - 1.5e-13 49.2 28.5 0.72 10.6 0.4 9.5 9 1 0 9 9 9 6 Leucine Rich Repeat LRR_6 PF13516.6 RLN90932.1 - 1.1e-07 31.3 11.3 0.26 11.4 0.0 7.0 8 0 0 8 8 8 4 Leucine Rich repeat Kelch_3 PF13415.6 RLN90933.1 - 2.6e-29 100.9 2.5 4.4e-10 39.6 0.0 6.3 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN90933.1 - 5.5e-23 80.5 0.8 0.0003 20.7 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 RLN90933.1 - 5.5e-19 67.9 5.1 0.0015 18.5 0.0 5.8 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.6 RLN90933.1 - 1.1e-18 66.8 0.9 0.00025 21.2 0.0 5.6 4 1 1 5 5 5 4 Kelch motif Kelch_2 PF07646.15 RLN90933.1 - 3.8e-12 45.7 4.9 0.00029 20.7 0.1 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 RLN90933.1 - 2.5e-11 43.0 7.7 0.0023 17.5 0.0 6.0 7 0 0 7 7 7 4 Kelch motif TPR_1 PF00515.28 RLN90933.1 - 8.7e-08 31.7 1.0 0.0013 18.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN90933.1 - 8.9e-08 31.7 0.3 2.1e-06 27.3 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 RLN90933.1 - 0.00016 21.5 0.6 0.014 15.5 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN90933.1 - 0.00035 21.2 0.4 0.2 12.6 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat RAG2 PF03089.14 RLN90933.1 - 0.0024 16.9 0.0 0.84 8.6 0.0 3.5 3 2 0 3 3 3 1 Recombination activating protein 2 TPR_8 PF13181.6 RLN90933.1 - 0.0051 16.9 0.0 0.25 11.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN90933.1 - 0.018 15.4 0.4 0.066 13.6 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN90933.1 - 0.17 12.6 2.2 0.17 12.6 0.4 2.0 2 0 0 2 2 1 0 Tetratricopeptide repeat HhH-GPD PF00730.25 RLN90935.1 - 7.9e-21 74.5 0.0 1.1e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 RLN90935.1 - 2.2e-07 30.4 0.0 5.8e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_8 PF14716.6 RLN90935.1 - 0.00062 20.1 0.0 0.0015 18.9 0.0 1.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.9 RLN90935.1 - 0.001 19.3 7.7 0.0017 18.6 7.7 1.4 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH_5 PF14520.6 RLN90935.1 - 0.0029 18.2 0.1 0.046 14.3 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain MSC PF09402.10 RLN90935.1 - 0.016 14.7 0.1 0.022 14.2 0.1 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain HRDC PF00570.23 RLN90935.1 - 0.088 12.8 0.1 6.6 6.8 0.0 2.6 2 0 0 2 2 2 0 HRDC domain FKBP_C PF00254.28 RLN90936.1 - 3.2e-31 107.5 0.0 4.2e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_16 PF13432.6 RLN90937.1 - 6.4e-10 39.5 22.6 0.0066 17.1 0.2 6.1 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 RLN90937.1 - 2.3e-09 36.7 2.9 0.026 14.7 0.1 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN90937.1 - 6.4e-08 32.1 4.8 0.14 12.0 0.1 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN90937.1 - 3.1e-07 30.7 19.8 0.012 16.4 0.1 6.4 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 RLN90937.1 - 4.2e-07 30.4 12.2 0.071 13.6 0.2 5.5 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN90937.1 - 3e-05 23.8 18.0 0.36 11.1 0.2 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN90937.1 - 0.0012 19.0 5.6 0.13 12.5 1.5 4.3 4 2 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 RLN90937.1 - 0.0043 16.7 5.5 4.1 7.2 0.0 5.9 7 0 0 7 7 7 1 TPR repeat TPR_7 PF13176.6 RLN90937.1 - 0.034 14.2 10.8 0.24 11.5 0.1 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN90937.1 - 0.069 13.8 6.8 53 4.8 0.0 5.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 RLN90937.1 - 0.14 12.3 8.5 1.6 9.0 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 RLN90937.1 - 1.2 8.8 10.0 1 9.1 0.3 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat-like domain Pkinase PF00069.25 RLN90938.1 - 8.2e-19 68.0 0.1 1.1e-18 67.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain PX PF00787.24 RLN90938.1 - 3.8e-13 49.4 0.7 2e-12 47.1 0.4 2.0 2 0 0 2 2 2 1 PX domain Pkinase_Tyr PF07714.17 RLN90938.1 - 4.5e-11 42.5 0.1 6.4e-11 42.0 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DLH PF01738.18 RLN90938.1 - 0.0049 16.5 0.0 0.0078 15.8 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family DMRT-like PF15791.5 RLN90938.1 - 0.044 14.2 5.2 0.12 12.7 5.2 1.8 1 0 0 1 1 1 0 Doublesex-and mab-3-related transcription factor C1 and C2 PRIMA1 PF16101.5 RLN90940.1 - 0.15 12.1 0.2 0.31 11.1 0.2 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Kinesin PF00225.23 RLN90941.1 - 3.7e-66 223.3 11.3 2e-61 207.8 0.6 3.4 3 1 1 4 4 3 2 Kinesin motor domain AAA PF00004.29 RLN90941.1 - 3.4e-19 69.6 0.0 4.1e-17 62.8 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Microtub_bd PF16796.5 RLN90941.1 - 1.9e-15 57.1 0.1 4.5e-15 55.9 0.1 1.7 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 RLN90941.1 - 2.9e-10 40.8 0.9 0.00044 20.7 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 RLN90941.1 - 5e-06 26.8 0.0 0.095 13.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 RLN90941.1 - 0.00019 21.5 0.0 0.39 10.7 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 RLN90941.1 - 0.00027 20.3 0.0 0.65 9.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.6 RLN90941.1 - 0.00037 20.7 0.2 0.066 13.4 0.0 3.4 3 1 0 3 3 3 1 AAA domain RuvB_N PF05496.12 RLN90941.1 - 0.00086 19.1 0.0 0.0026 17.5 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RLN90941.1 - 0.00092 19.2 0.3 0.065 13.2 0.0 3.2 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 RLN90941.1 - 0.0011 19.4 0.0 1.5 9.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 RLN90941.1 - 0.0018 17.8 0.0 1.5 8.3 0.0 2.9 3 0 0 3 3 3 1 P-loop containing dynein motor region NACHT PF05729.12 RLN90941.1 - 0.002 18.1 0.1 0.45 10.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Sigma54_activ_2 PF14532.6 RLN90941.1 - 0.003 17.7 0.0 0.047 13.8 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 RLN90941.1 - 0.0031 18.1 1.6 3.1 8.4 0.0 4.4 4 0 0 4 4 4 1 AAA domain AAA_28 PF13521.6 RLN90941.1 - 0.0039 17.5 0.0 0.12 12.6 0.0 3.2 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 RLN90941.1 - 0.0059 16.3 0.4 1.9 8.2 0.0 3.3 3 1 0 3 3 3 1 Sigma-54 interaction domain AAA_24 PF13479.6 RLN90941.1 - 0.0081 15.9 0.2 13 5.5 0.0 3.9 3 1 1 4 4 4 0 AAA domain ResIII PF04851.15 RLN90941.1 - 0.014 15.4 0.0 7.3 6.6 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 RLN90941.1 - 0.022 14.5 0.0 3.1 7.5 0.0 2.6 3 0 0 3 3 2 0 IstB-like ATP binding protein Zot PF05707.12 RLN90941.1 - 0.023 14.4 0.3 5.3 6.6 0.0 3.3 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) AAA_30 PF13604.6 RLN90941.1 - 0.029 14.1 10.4 1.1 8.9 0.0 4.0 3 2 0 3 3 3 0 AAA domain CDC45 PF02724.14 RLN90941.1 - 0.038 12.3 7.7 0.0068 14.8 4.0 1.6 2 0 0 2 2 2 0 CDC45-like protein Bac_DnaA PF00308.18 RLN90941.1 - 0.038 13.8 0.1 0.089 12.6 0.1 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein TFIIA PF03153.13 RLN90941.1 - 0.039 14.0 11.4 0.099 12.6 11.4 1.7 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TIP49 PF06068.13 RLN90941.1 - 0.049 12.8 0.0 0.88 8.7 0.0 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain Mg_chelatase PF01078.21 RLN90941.1 - 0.11 11.8 0.2 1.7 7.9 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 RLN90941.1 - 0.13 11.7 0.1 22 4.4 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein DUF87 PF01935.17 RLN90941.1 - 0.44 10.6 1.7 2.8 8.0 0.0 3.1 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_11 PF13086.6 RLN90941.1 - 0.59 9.9 0.0 0.59 9.9 0.0 3.8 5 1 0 5 5 4 0 AAA domain Nop14 PF04147.12 RLN90941.1 - 2 6.6 16.9 3.9 5.6 16.9 1.4 1 0 0 1 1 1 0 Nop14-like family RRM_1 PF00076.22 RLN90943.1 - 2e-10 40.3 0.0 3.1e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 RLN90943.1 - 0.01 15.9 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 DUF2457 PF10446.9 RLN90943.1 - 0.024 13.8 10.1 0.037 13.2 10.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FimA PF16970.5 RLN90943.1 - 0.039 14.1 0.1 0.055 13.7 0.1 1.2 1 0 0 1 1 1 0 Type-1 fimbrial protein, A CcmF_C PF16327.5 RLN90943.1 - 0.087 12.1 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal DUF4131 PF13567.6 RLN90943.1 - 0.15 11.7 0.2 0.27 10.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) RRM_3 PF08777.11 RLN90943.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif DUF1177 PF06675.11 RLN90943.1 - 0.31 9.8 2.2 0.44 9.3 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) zf-RING_2 PF13639.6 RLN90944.1 - 1.5e-10 41.3 12.9 2.8e-10 40.4 12.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN90944.1 - 8e-10 38.4 12.7 1.5e-09 37.6 12.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN90944.1 - 1.9e-06 27.7 10.3 3.4e-06 26.8 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN90944.1 - 6e-06 26.0 13.1 1.1e-05 25.2 13.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN90944.1 - 6.2e-06 26.1 6.5 6.2e-06 26.1 6.5 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN90944.1 - 1e-05 25.4 12.0 1.9e-05 24.5 12.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 RLN90944.1 - 1.4e-05 25.2 11.7 4.6e-05 23.6 11.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 RLN90944.1 - 4.4e-05 23.1 13.7 9.5e-05 22.1 11.4 2.3 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 RLN90944.1 - 0.00027 20.7 10.8 0.00055 19.8 10.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 RLN90944.1 - 0.006 16.4 7.0 0.017 14.9 7.0 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 RLN90944.1 - 0.015 14.9 9.1 0.027 14.1 9.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 RLN90944.1 - 0.019 15.0 3.7 0.041 13.9 3.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 RLN90944.1 - 0.024 14.5 10.1 0.33 10.9 5.1 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 DUF1757 PF08560.10 RLN90944.1 - 0.029 14.4 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) zf-Nse PF11789.8 RLN90944.1 - 0.13 12.1 5.9 0.27 11.1 5.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 RLN90944.1 - 0.13 12.1 3.9 0.32 10.9 3.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Leu_zip PF15294.6 RLN90944.1 - 0.16 11.5 8.5 0.069 12.7 1.5 2.1 1 1 1 2 2 2 0 Leucine zipper DEDD_Tnp_IS110 PF01548.17 RLN90944.1 - 0.25 11.2 4.4 0.59 10.0 0.1 2.4 2 0 0 2 2 2 0 Transposase zf-TFIIIC PF12660.7 RLN90944.1 - 0.3 11.1 2.5 0.25 11.3 0.7 1.8 2 0 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex APG6_N PF17675.1 RLN90944.1 - 0.58 10.7 11.3 0.13 12.8 6.1 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Rtf2 PF04641.12 RLN90944.1 - 0.97 8.7 9.0 0.039 13.3 1.3 2.4 2 0 0 2 2 2 0 Rtf2 RING-finger DivIC PF04977.15 RLN90944.1 - 3.2 7.6 7.6 0.46 10.3 2.9 2.1 2 0 0 2 2 2 0 Septum formation initiator zf-C3HC4_4 PF15227.6 RLN90944.1 - 3.8 7.7 8.5 11 6.2 8.5 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zf_RING PF16744.5 RLN90944.1 - 4.9 7.3 8.2 2.8 8.1 5.5 1.9 1 1 0 1 1 1 0 KIAA1045 RING finger Ribosomal_L38e PF01781.18 RLN90945.1 - 6.1e-32 109.5 3.8 7.9e-32 109.2 3.8 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Aminotran_1_2 PF00155.21 RLN90946.1 - 0.025 13.8 0.0 0.032 13.4 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Aminotran_1_2 PF00155.21 RLN90947.1 - 8.5e-17 61.4 0.0 1.2e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II HTH_psq PF05225.16 RLN90947.1 - 5.4e-14 51.7 0.1 1.5e-13 50.2 0.1 1.8 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_ISL3 PF13542.6 RLN90947.1 - 0.00076 18.8 0.4 0.002 17.5 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 RLN90947.1 - 0.0042 17.2 0.3 0.0042 17.2 0.3 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 RLN90947.1 - 0.047 13.5 1.2 0.087 12.6 0.1 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_1 PF01527.20 RLN90947.1 - 0.068 13.5 0.1 0.19 12.0 0.1 1.8 1 0 0 1 1 1 0 Transposase Sigma70_r4_2 PF08281.12 RLN90947.1 - 0.14 11.9 1.6 0.7 9.6 0.1 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 DUF4203 PF13886.6 RLN90948.1 - 6.1e-32 110.9 25.9 7.5e-32 110.6 25.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Caps_synth_CapC PF14102.6 RLN90948.1 - 0.53 10.7 12.4 0.13 12.7 8.7 1.9 2 0 0 2 2 2 0 Capsule biosynthesis CapC YlaH PF14036.6 RLN90948.1 - 3.2 8.2 7.5 0.38 11.1 0.9 2.4 3 0 0 3 3 3 0 YlaH-like protein LPP PF04728.13 RLN90949.1 - 5.7 7.4 7.5 24 5.4 0.5 2.9 3 0 0 3 3 3 0 Lipoprotein leucine-zipper RSRP PF17069.5 RLN90950.1 - 0.91 9.0 16.8 1.5 8.4 16.8 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 JAB PF01398.21 RLN90951.1 - 4e-21 75.2 0.2 6.1e-21 74.6 0.2 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 RLN90951.1 - 6.5e-18 65.2 0.0 2e-17 63.6 0.0 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Herpes_US9 PF06072.11 RLN90952.1 - 0.069 13.0 0.0 4.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 PUMA PF15826.5 RLN90952.1 - 0.078 13.2 0.4 0.13 12.4 0.4 1.3 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis DUF433 PF04255.14 RLN90952.1 - 0.25 11.2 0.7 2.9 7.8 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF433) PHO4 PF01384.20 RLN90954.1 - 1.4e-34 119.6 24.5 6.1e-18 65.0 8.5 3.9 2 1 2 4 4 4 4 Phosphate transporter family Sugar_tr PF00083.24 RLN90955.1 - 4.7e-88 296.0 19.6 5.9e-88 295.7 19.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN90955.1 - 2e-26 92.8 33.3 1.1e-24 87.1 31.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GWT1 PF06423.12 RLN90955.1 - 0.033 14.3 0.6 0.12 12.5 0.6 2.0 1 1 0 1 1 1 0 GWT1 DUF2711 PF10924.8 RLN90955.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) DUF3638 PF12340.8 RLN90956.1 - 6.7e-59 199.0 0.0 1.4e-58 197.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 RLN90956.1 - 1.6e-15 56.2 0.0 4.4e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) DUF3450 PF11932.8 RLN90957.1 - 0.51 9.6 13.2 0.088 12.1 6.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) YabA PF06156.13 RLN90957.1 - 0.56 10.9 3.2 2.5 8.8 0.1 2.4 2 0 0 2 2 2 0 Initiation control protein YabA Com_YlbF PF06133.11 RLN90957.1 - 1.5 9.5 8.0 6.1 7.5 0.7 2.6 3 0 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA CENP-F_leu_zip PF10473.9 RLN90957.1 - 2.4 8.2 13.6 24 5.0 11.9 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pkinase PF00069.25 RLN90958.1 - 1.7e-29 103.0 0.1 4.7e-29 101.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90958.1 - 3.8e-14 52.6 0.0 6.8e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PsbI PF02532.14 RLN90958.1 - 0.12 12.4 0.6 0.3 11.0 0.6 1.7 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Pkinase PF00069.25 RLN90959.1 - 2e-48 165.1 0.0 2.6e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90959.1 - 7.7e-43 146.6 0.0 9.7e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN90959.1 - 0.027 14.4 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Scramblase PF03803.15 RLN90959.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Scramblase ATP_bind_1 PF03029.17 RLN90960.1 - 2.4e-75 253.4 0.5 4.6e-75 252.5 0.1 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 RLN90960.1 - 6.3e-09 35.7 0.0 4.9e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 RLN90960.1 - 2.1e-06 27.3 0.0 0.00013 21.5 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 RLN90960.1 - 6.3e-05 22.1 0.1 0.014 14.4 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 RLN90960.1 - 0.00011 22.2 0.0 0.0004 20.5 0.0 1.9 2 1 0 2 2 1 1 50S ribosome-binding GTPase cobW PF02492.19 RLN90960.1 - 0.00058 19.5 0.0 0.22 11.1 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 RLN90960.1 - 0.00087 19.2 0.1 0.0019 18.1 0.1 1.5 1 0 0 1 1 1 1 NACHT domain G-alpha PF00503.20 RLN90960.1 - 0.0016 17.7 0.0 0.94 8.6 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit NB-ARC PF00931.22 RLN90960.1 - 0.002 17.4 0.0 0.0051 16.0 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 RLN90960.1 - 0.0031 17.9 0.1 0.0094 16.3 0.0 2.0 1 1 0 2 2 2 1 AAA ATPase domain SRP54 PF00448.22 RLN90960.1 - 0.0042 16.7 0.1 0.0095 15.6 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 RLN90960.1 - 0.0046 16.9 0.0 3.7 7.4 0.0 2.8 3 0 0 3 3 2 1 RsgA GTPase AAA_18 PF13238.6 RLN90960.1 - 0.0051 17.4 0.2 0.048 14.2 0.0 2.4 3 0 0 3 3 2 1 AAA domain Arf PF00025.21 RLN90960.1 - 0.006 16.0 0.0 0.75 9.2 0.0 2.5 2 1 0 2 2 2 1 ADP-ribosylation factor family PhoH PF02562.16 RLN90960.1 - 0.0086 15.5 0.0 0.68 9.4 0.0 2.6 3 0 0 3 3 3 1 PhoH-like protein PduV-EutP PF10662.9 RLN90960.1 - 0.015 15.0 0.5 0.16 11.7 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 RLN90960.1 - 0.016 15.5 0.1 0.14 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 RLN90960.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RLN90960.1 - 0.02 15.1 0.3 0.056 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 RLN90960.1 - 0.027 14.3 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 RLN90960.1 - 0.03 14.0 0.2 0.059 13.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain Gtr1_RagA PF04670.12 RLN90960.1 - 0.043 13.2 0.0 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region MobB PF03205.14 RLN90960.1 - 0.048 13.6 0.4 0.14 12.1 0.0 1.9 3 0 0 3 3 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 RLN90960.1 - 0.061 13.1 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase CbiA PF01656.23 RLN90960.1 - 0.072 13.1 0.0 0.1 12.6 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 RLN90960.1 - 0.076 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 RLN90960.1 - 0.09 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 RLN90960.1 - 0.093 13.2 0.2 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 RLN90960.1 - 0.098 12.2 0.4 1.2 8.6 0.0 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain NTPase_1 PF03266.15 RLN90960.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NTPase ATPase PF06745.13 RLN90960.1 - 0.12 11.7 0.2 0.43 9.9 0.1 2.0 2 1 1 3 3 3 0 KaiC DUF87 PF01935.17 RLN90960.1 - 0.12 12.4 0.2 0.81 9.7 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain Roc PF08477.13 RLN90960.1 - 0.13 12.4 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PP2C_C PF07830.13 RLN90960.1 - 0.2 12.1 0.4 0.41 11.1 0.4 1.5 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain Aminotran_5 PF00266.19 RLN90962.1 - 2.7e-32 112.2 0.0 3.3e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 RLN90962.1 - 1.9e-09 37.3 0.1 2.8e-09 36.7 0.1 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 RLN90962.1 - 3.5e-06 25.8 0.0 4.9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 RLN90962.1 - 6.5e-06 25.5 0.0 8.7e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2722 PF10846.8 RLN90962.1 - 0.03 13.3 0.4 0.032 13.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Peptidase_C107 PF17222.3 RLN90962.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Viral cysteine endopeptidase C107 SGL PF08450.12 RLN90963.1 - 1.8e-40 139.1 0.1 2.3e-40 138.8 0.1 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 RLN90963.1 - 0.0034 17.5 0.0 0.033 14.3 0.0 2.5 2 0 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.20 RLN90963.1 - 0.0038 17.4 0.0 0.1 12.8 0.0 2.4 2 0 0 2 2 2 1 Arylesterase Lactonase PF10282.9 RLN90963.1 - 0.12 11.5 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Glyoxalase_4 PF13669.6 RLN90966.1 - 2.2e-19 69.7 0.0 3.7e-19 69.0 0.0 1.4 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 RLN90966.1 - 0.1 12.8 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DD_K PF12121.8 RLN90967.1 - 0.61 10.3 2.0 2 8.6 1.1 2.2 2 0 0 2 2 2 0 Dermaseptin zf-NOSIP PF15906.5 RLN90970.1 - 9.7e-11 41.7 0.1 1.7e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_2 PF13639.6 RLN90970.1 - 0.0013 19.0 2.3 0.086 13.2 0.2 2.4 2 0 0 2 2 2 2 Ring finger domain zinc_ribbon_13 PF09855.9 RLN90970.1 - 0.085 13.0 0.1 12 6.1 0.1 2.6 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-RING_UBOX PF13445.6 RLN90970.1 - 0.1 12.6 3.6 0.13 12.3 0.3 2.3 2 0 0 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.6 RLN90970.1 - 0.18 11.7 3.1 4.1 7.3 1.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF2093 PF09866.9 RLN90970.1 - 0.23 10.9 1.6 3.2 7.3 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2093) CLN3 PF02487.17 RLN90971.1 - 1.1e-78 265.1 11.0 1.3e-78 264.8 11.0 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 RLN90971.1 - 0.52 9.2 45.9 1.1 8.1 45.7 1.6 1 1 0 1 1 1 0 Major Facilitator Superfamily zf-primase PF09329.11 RLN90972.1 - 0.0009 19.0 0.1 0.0009 19.0 0.1 1.6 2 0 0 2 2 2 1 Primase zinc finger FAM76 PF16046.5 RLN90972.1 - 0.12 11.7 0.2 0.16 11.3 0.2 1.1 1 0 0 1 1 1 0 FAM76 protein K_channel_TID PF07941.11 RLN90972.1 - 4.9 7.7 10.6 1.1 9.7 3.8 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain PDZ PF00595.24 RLN90973.1 - 2.4e-10 40.6 0.2 0.00047 20.5 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 RLN90973.1 - 1.8e-09 37.3 0.0 5.1e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PH PF00169.29 RLN90973.1 - 0.00012 22.5 0.2 0.00024 21.6 0.2 1.5 1 0 0 1 1 1 1 PH domain zf-RanBP PF00641.18 RLN90973.1 - 0.00082 18.6 1.6 0.0016 17.7 1.6 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others PDZ_2 PF13180.6 RLN90973.1 - 0.0017 18.7 0.5 1.5 9.2 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PH_11 PF15413.6 RLN90973.1 - 0.04 14.3 1.9 0.094 13.2 0.5 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain SirA PF10747.9 RLN90973.1 - 0.19 12.0 0.1 0.3 11.4 0.1 1.2 1 0 0 1 1 1 0 Sporulation inhibitor of replication protein SirA zf-C2HC5 PF06221.13 RLN90974.1 - 0.0015 18.5 0.2 0.0034 17.3 0.2 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type ELMO_CED12 PF04727.13 RLN90975.1 - 1.7e-36 126.0 0.0 3e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family RUN PF02759.19 RLN90975.1 - 6.8e-17 61.7 0.0 2.2e-16 60.0 0.0 1.9 1 0 0 1 1 1 1 RUN domain RhoGAP PF00620.27 RLN90975.1 - 2.2e-15 56.8 0.0 4.9e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain STG PF15809.5 RLN90976.1 - 0.048 13.7 1.1 0.067 13.3 0.8 1.4 1 1 0 1 1 1 0 Simian taste bud-specific gene product family DUF2334 PF10096.9 RLN90976.1 - 0.13 11.8 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Golgin_A5 PF09787.9 RLN90977.1 - 1e-20 74.4 41.3 1.9e-20 73.6 9.1 2.7 1 1 1 2 2 2 2 Golgin subfamily A member 5 CASP_C PF08172.12 RLN90977.1 - 1.8e-05 24.3 1.2 1.8e-05 24.3 1.2 4.9 2 1 1 3 3 3 1 CASP C terminal TMF_DNA_bd PF12329.8 RLN90977.1 - 0.0046 16.9 7.0 0.0046 16.9 7.0 6.2 3 2 4 7 7 7 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 RLN90977.1 - 0.24 11.6 57.7 1.1 9.4 17.3 4.3 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 RLN90977.1 - 1.6 8.8 40.5 0.034 14.3 11.6 3.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 RLN90977.1 - 1.6 8.9 36.1 0.029 14.5 10.9 4.1 2 1 3 5 5 5 0 Fibrinogen alpha/beta chain family PKcGMP_CC PF16808.5 RLN90977.1 - 4.5 7.2 7.9 6.6 6.7 1.0 3.6 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Fez1 PF06818.15 RLN90977.1 - 7.1 7.0 47.3 4.4 7.7 23.6 3.3 1 1 1 2 2 2 0 Fez1 SlyX PF04102.12 RLN90977.1 - 7.6 7.2 34.8 1.2 9.8 3.0 7.0 3 2 3 6 6 6 0 SlyX Atg14 PF10186.9 RLN90977.1 - 7.8 5.5 39.5 1 8.4 11.9 2.7 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SET PF00856.28 RLN90980.1 - 1.6e-12 48.1 0.0 1.6e-12 48.1 0.0 3.9 3 2 0 3 3 3 1 SET domain preSET_CXC PF18264.1 RLN90980.1 - 4.7e-10 39.8 14.9 4.7e-10 39.8 14.9 3.1 2 1 0 2 2 2 1 CXC domain Mito_carr PF00153.27 RLN90981.1 - 3.6e-51 171.1 3.6 4.5e-19 68.2 0.1 3.9 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 RLN90981.1 - 0.014 14.5 0.6 8.1 5.5 0.0 3.5 4 0 0 4 4 4 0 Gammaproteobacterial serine protease HMD PF03201.16 RLN90981.1 - 0.051 13.8 0.0 16 5.8 0.0 2.4 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Pkinase_Tyr PF07714.17 RLN90984.1 - 7.1e-40 136.9 0.0 1.3e-39 136.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN90984.1 - 2e-33 115.9 0.0 3.6e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.23 RLN90984.1 - 1.4e-12 47.2 2.0 0.0086 16.1 0.0 5.6 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat DZR PF12773.7 RLN90984.1 - 0.00047 20.1 0.2 0.0011 19.0 0.2 1.5 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 RLN90984.1 - 0.0022 17.6 0.4 0.0043 16.7 0.4 1.5 1 0 0 1 1 1 1 zinc-ribbon domain ABC1 PF03109.16 RLN90984.1 - 0.0025 18.0 0.0 0.0068 16.6 0.0 1.7 1 0 0 1 1 1 1 ABC1 family zinc_ribbon_15 PF17032.5 RLN90984.1 - 0.0073 17.0 1.1 0.017 15.9 1.1 1.6 1 0 0 1 1 1 1 zinc-ribbon family DUF123 PF01986.16 RLN90984.1 - 0.031 14.8 0.0 0.6 10.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF123 zf-ribbon_3 PF13248.6 RLN90984.1 - 0.085 12.3 0.7 0.18 11.3 0.7 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Nudix_N_2 PF14803.6 RLN90984.1 - 0.12 12.3 2.2 0.59 10.1 0.1 2.9 3 0 0 3 3 3 0 Nudix N-terminal APH PF01636.23 RLN90984.1 - 0.15 11.9 2.1 0.43 10.5 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family HEAT_EZ PF13513.6 RLN90984.1 - 0.17 12.4 5.5 1.3 9.6 0.1 3.6 1 1 3 4 4 4 0 HEAT-like repeat DUF4795 PF16043.5 RLN90985.1 - 0.0011 18.6 16.0 0.0013 18.3 16.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) OstA_2 PF13100.6 RLN90985.1 - 0.071 12.7 0.3 0.082 12.5 0.3 1.3 1 0 0 1 1 1 0 OstA-like protein DUF648 PF04890.13 RLN90985.1 - 0.16 11.7 9.5 0.18 11.5 9.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF648) SseC PF04888.12 RLN90985.1 - 0.43 10.1 9.5 0.66 9.5 9.5 1.4 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family DUF3584 PF12128.8 RLN90985.1 - 0.83 7.1 27.0 0.96 6.9 27.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SLATT_6 PF18169.1 RLN90985.1 - 1.1 8.8 4.0 0.95 9.0 0.5 2.0 1 1 2 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 6 COG2 PF06148.11 RLN90985.1 - 1.6 8.8 13.5 2 8.5 4.5 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Phage_HK97_TLTM PF06120.11 RLN90985.1 - 1.9 7.6 11.9 2.2 7.4 2.4 2.1 2 0 0 2 2 2 0 Tail length tape measure protein Sec66 PF09802.9 RLN90985.1 - 2.4 7.7 11.3 0.96 9.0 1.2 2.2 1 1 1 2 2 2 0 Preprotein translocase subunit Sec66 GIT_CC PF16559.5 RLN90985.1 - 8.1 6.4 15.2 0.078 12.9 4.8 2.6 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor RyR PF02026.16 RLN90987.1 - 2.3e-42 143.1 0.0 3.8e-21 75.1 0.0 2.5 2 0 0 2 2 2 2 RyR domain Pkinase PF00069.25 RLN90987.1 - 2.6e-39 135.2 0.0 3.5e-38 131.5 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN90987.1 - 2.3e-18 66.4 0.0 3.6e-08 33.0 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase PH PF00169.29 RLN90987.1 - 1.4e-05 25.5 0.0 3.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 PH domain APH PF01636.23 RLN90987.1 - 0.016 15.2 0.2 1.2 9.1 0.0 2.4 1 1 0 2 2 2 0 Phosphotransferase enzyme family Sdh_cyt PF01127.22 RLN90988.1 - 2.9e-05 24.1 0.3 3.7e-05 23.7 0.3 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF948 PF06103.11 RLN90989.1 - 0.047 13.9 5.8 1.2 9.5 0.1 3.5 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) MCC-bdg_PDZ PF10506.9 RLN90989.1 - 0.63 10.1 13.3 0.23 11.5 4.2 3.9 2 2 1 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome FlaC_arch PF05377.11 RLN90989.1 - 7.4 7.1 6.4 28 5.2 0.3 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) S1-P1_nuclease PF02265.16 RLN90990.1 - 2.4e-36 125.8 0.0 3.1e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease zf-C2H2 PF00096.26 RLN90992.1 - 4.3e-14 52.1 26.5 0.00014 22.1 1.5 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN90992.1 - 1.1e-13 50.7 23.1 0.00042 20.9 0.9 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RLN90992.1 - 7.8e-10 38.7 28.0 0.0014 19.0 1.3 5.0 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RLN90992.1 - 6.4e-06 26.3 2.2 0.3 11.4 0.0 4.3 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 RLN90992.1 - 0.0014 18.3 15.2 0.071 12.9 0.7 4.5 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-met PF12874.7 RLN90992.1 - 0.006 16.9 6.0 1 9.8 0.1 4.5 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 RLN90992.1 - 0.012 15.9 9.3 0.7 10.2 2.0 3.0 1 1 0 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_9 PF16293.5 RLN90992.1 - 0.24 11.3 7.7 14 5.6 0.1 4.0 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) FOXP-CC PF16159.5 RLN90992.1 - 0.24 12.0 7.1 2.9 8.6 0.1 2.9 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 RLN90992.1 - 1.1 9.4 7.4 20 5.3 0.2 3.1 1 1 3 4 4 4 0 Aberrant zinc-finger Ogr_Delta PF04606.12 RLN90992.1 - 5.5 7.0 8.0 10 6.2 1.0 2.9 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger CHORD PF04968.12 RLN90992.1 - 9 7.1 10.1 3.9 8.3 0.2 3.2 2 2 2 4 4 4 0 CHORD zf-C2H2 PF00096.26 RLN90993.1 - 1.5e-24 85.0 22.8 4.4e-06 26.9 0.4 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RLN90993.1 - 1.3e-17 63.3 21.0 6.8e-06 26.3 0.1 5.3 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 RLN90993.1 - 5.4e-17 61.0 19.5 0.0012 19.5 0.8 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RLN90993.1 - 3.3e-08 33.3 12.6 0.019 15.0 0.2 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RLN90993.1 - 2.5e-06 27.6 6.8 0.16 12.3 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 RLN90993.1 - 5.3e-05 22.9 17.1 0.097 12.4 0.1 4.8 4 1 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 RLN90993.1 - 0.00012 21.8 17.1 0.041 13.6 0.6 4.3 4 0 0 4 4 4 3 zinc-finger C2H2-type zf-TRAF PF02176.18 RLN90993.1 - 0.00018 22.1 4.8 0.085 13.6 0.2 2.4 2 0 0 2 2 2 2 TRAF-type zinc finger zf_ZIC PF18366.1 RLN90993.1 - 0.00022 21.3 3.6 1.4 9.1 0.2 4.2 3 1 1 4 4 4 1 Zic proteins zinc finger domain FOXP-CC PF16159.5 RLN90993.1 - 0.0014 19.2 4.0 0.33 11.6 0.1 3.4 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 RLN90993.1 - 0.0038 17.5 8.4 0.031 14.6 5.3 2.5 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 RLN90993.1 - 0.014 15.5 2.3 8.3 6.5 0.0 3.2 2 1 1 3 3 3 0 Aberrant zinc-finger zf-Di19 PF05605.12 RLN90993.1 - 0.03 14.6 8.8 0.52 10.6 1.5 3.2 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 RLN90993.1 - 0.04 14.3 10.0 0.47 10.9 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RLN90993.1 - 0.12 12.8 9.5 13 6.2 0.5 3.5 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) DUF4729 PF15866.5 RLN90993.1 - 0.53 9.6 7.3 0.29 10.4 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4729) Zn_ribbon_SprT PF17283.2 RLN90993.1 - 1.9 8.5 6.4 1.3 9.0 3.0 2.5 1 1 1 2 2 2 0 SprT-like zinc ribbon domain Iso_dh PF00180.20 RLN90994.1 - 1.9e-68 231.2 0.0 2.4e-68 230.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HECT PF00632.25 RLN90995.1 - 2e-62 211.4 0.0 8.8e-62 209.3 0.0 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 RLN90995.1 - 0.074 13.1 4.1 18 5.6 0.0 4.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Solute_trans_a PF03619.16 RLN90996.1 - 1.2e-77 261.0 16.6 1.6e-77 260.6 16.6 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha LCAT PF02450.15 RLN90996.1 - 0.21 10.7 0.1 0.37 9.9 0.1 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 RLN90996.1 - 1.1 9.8 5.9 0.64 10.6 2.5 2.4 1 1 0 2 2 2 0 Alpha/beta hydrolase family Aa_trans PF01490.18 RLN90997.1 - 1.5e-41 142.5 15.7 2.2e-41 141.9 15.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ribosomal_L29 PF00831.23 RLN90999.1 - 0.06 13.3 0.5 0.06 13.3 0.5 2.1 2 0 0 2 2 2 0 Ribosomal L29 protein Pkip-1 PF06878.11 RLN90999.1 - 0.14 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Pkip-1 protein AMP-binding PF00501.28 RLN91000.1 - 3.4e-72 243.4 0.0 3.9e-67 226.7 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 RLN91000.1 - 3.4e-12 47.2 0.2 8.2e-12 45.9 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain VitD-bind_III PF09164.10 RLN91000.1 - 0.013 15.4 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 Vitamin D binding protein, domain III AMP-binding PF00501.28 RLN91001.1 - 2e-68 230.9 0.0 2.6e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN91001.1 - 1.1e-14 55.2 1.2 1.7e-14 54.6 0.4 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 RLN91002.1 - 5.5e-93 311.8 0.0 7.4e-92 308.1 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN91002.1 - 1.1e-13 52.0 0.1 4.5e-13 50.0 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GFA PF04828.14 RLN91003.1 - 6.2e-10 39.3 1.0 6.2e-10 39.3 1.0 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L37e PF01907.19 RLN91003.1 - 0.0091 16.1 0.3 0.021 15.0 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e AMP-binding PF00501.28 RLN91005.1 - 3e-89 299.6 0.0 3.5e-89 299.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN91005.1 - 8.1e-15 55.6 1.0 1.8e-14 54.5 0.2 2.1 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 RLN91006.1 - 1e-83 281.3 0.0 6.3e-83 278.7 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN91006.1 - 4.3e-13 50.0 0.1 2.7e-12 47.5 0.0 2.4 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain DUF2605 PF10792.9 RLN91007.1 - 0.00081 19.3 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2605) F-box-like PF12937.7 RLN91007.1 - 0.028 14.3 0.2 0.083 12.8 0.2 1.9 1 0 0 1 1 1 0 F-box-like ABC_membrane PF00664.23 RLN91009.1 - 9.6e-25 87.8 8.9 1.2e-24 87.5 8.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN91009.1 - 1.4e-05 25.7 0.2 2.7e-05 24.7 0.2 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 RLN91009.1 - 0.034 14.5 0.0 0.082 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 RLN91009.1 - 0.089 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 RLN91009.1 - 0.11 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 RLN91009.1 - 0.14 12.0 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase ABC_membrane PF00664.23 RLN91010.1 - 3.9e-26 92.3 7.3 5.5e-26 91.8 7.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN91010.1 - 1.2e-05 25.8 0.2 2.7e-05 24.7 0.2 1.6 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 RLN91010.1 - 0.1 12.9 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 RLN91010.1 - 0.14 11.3 0.1 0.21 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 RLN91010.1 - 0.15 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 RLN91010.1 - 0.17 12.3 0.1 0.38 11.1 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain Phage_tail_X PF05489.12 RLN91011.1 - 0.04 13.6 0.0 0.093 12.4 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X MMS19_N PF14500.6 RLN91011.1 - 2.2 7.8 8.5 1.5 8.4 0.1 3.4 2 1 1 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Sugar_tr PF00083.24 RLN91012.1 - 5.1e-07 28.9 0.0 5.1e-07 28.9 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1035 PF06281.12 RLN91012.1 - 0.088 12.8 0.2 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) Sugar_tr PF00083.24 RLN91013.1 - 2.9e-07 29.7 0.0 3.6e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN91013.1 - 0.044 12.7 0.2 0.05 12.5 0.2 1.2 1 1 0 1 1 1 0 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN91014.1 - 2.9e-07 29.7 0.0 3.6e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN91014.1 - 0.044 12.7 0.2 0.05 12.5 0.2 1.2 1 1 0 1 1 1 0 Major Facilitator Superfamily Pkinase PF00069.25 RLN91016.1 - 6.5e-31 107.6 0.0 6.2e-16 58.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN91016.1 - 2.2e-12 46.8 0.1 2.1e-09 37.1 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 RLN91016.1 - 0.048 13.6 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1295 PF06966.12 RLN91017.1 - 2.5e-47 161.4 11.2 3.3e-47 161.0 11.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Torus PF16131.5 RLN91017.1 - 9.6e-32 109.9 0.3 9.6e-32 109.9 0.3 1.8 2 0 0 2 2 1 1 Torus domain WW PF00397.26 RLN91017.1 - 1.3e-09 38.0 0.6 2.7e-09 36.9 0.6 1.6 1 0 0 1 1 1 1 WW domain RRM_1 PF00076.22 RLN91017.1 - 9.8e-07 28.5 0.0 1.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 RLN91017.1 - 5.1e-05 22.5 4.2 0.0001 21.5 4.2 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf_CCCH_4 PF18345.1 RLN91017.1 - 0.014 15.4 3.5 0.038 14.0 3.5 1.8 1 0 0 1 1 1 0 Zinc finger domain ICMT PF04140.14 RLN91017.1 - 0.021 15.2 0.0 0.079 13.4 0.0 1.9 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Glyco_hyd_101C PF17451.2 RLN91017.1 - 0.074 13.3 0.1 0.44 10.8 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain zf-CCCH PF00642.24 RLN91017.1 - 0.26 11.2 4.2 0.59 10.1 4.2 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Steroid_dh PF02544.16 RLN91017.1 - 0.66 10.0 10.5 0.073 13.1 5.1 2.0 2 1 1 3 3 3 0 3-oxo-5-alpha-steroid 4-dehydrogenase zf-CCCH_4 PF18044.1 RLN91017.1 - 1.5 8.7 6.8 3.3 7.6 6.8 1.6 1 0 0 1 1 1 0 CCCH-type zinc finger SRR1 PF07985.12 RLN91019.1 - 2.7e-13 49.7 0.0 6.8e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 SRR1 Kinesin PF00225.23 RLN91020.1 - 1.1e-102 343.4 1.5 1.6e-102 342.9 0.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RLN91020.1 - 6.6e-23 81.3 0.1 3e-18 66.2 0.0 3.1 3 0 0 3 3 3 2 Microtubule binding Myb_DNA-bind_3 PF12776.7 RLN91021.1 - 1.8e-05 25.6 0.0 5.3e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 RLN91021.1 - 0.04 14.3 0.0 0.1 13.0 0.0 1.8 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF573 PF04504.14 RLN91021.1 - 0.072 13.8 0.1 1.1 10.0 0.0 2.7 3 1 1 4 4 4 0 Protein of unknown function, DUF573 GREB1 PF15782.5 RLN91021.1 - 0.1 9.7 0.3 0.12 9.5 0.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Myb_DNA-bind_5 PF13873.6 RLN91021.1 - 0.16 12.1 0.0 0.44 10.6 0.0 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF2514 PF10721.9 RLN91021.1 - 0.27 11.2 5.9 0.11 12.5 2.5 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2514) MADF_DNA_bdg PF10545.9 RLN91021.1 - 0.3 11.4 2.2 1.8 8.9 0.0 2.8 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like ATP-synt_F6 PF05511.11 RLN91022.1 - 0.073 13.5 0.5 0.081 13.3 0.5 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 UCH PF00443.29 RLN91023.1 - 1.3e-54 185.4 0.0 2.1e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 RLN91023.1 - 1.3e-19 70.6 0.0 2.4e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 RLN91023.1 - 3.3e-10 40.1 0.0 0.0005 19.8 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase EF-hand_1 PF00036.32 RLN91023.1 - 0.00033 20.0 0.1 0.00082 18.8 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 RLN91023.1 - 0.00035 20.3 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN91023.1 - 0.0027 17.5 0.1 0.0098 15.8 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 RLN91023.1 - 0.0043 17.5 0.2 0.014 15.8 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN91023.1 - 0.0049 16.3 0.2 0.0049 16.3 0.2 2.4 2 0 0 2 2 2 1 EF hand Pkinase PF00069.25 RLN91024.1 - 3.8e-71 239.5 0.0 5.1e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN91024.1 - 3.4e-36 124.8 0.0 4.8e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN91024.1 - 0.0046 16.9 1.3 0.0059 16.6 0.2 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN91024.1 - 0.0052 15.6 0.0 0.012 14.4 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN91024.1 - 0.01 15.2 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 RLN91024.1 - 0.025 14.2 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Na_H_Exchanger PF00999.21 RLN91025.1 - 2.2e-35 122.2 39.3 3.1e-35 121.7 39.3 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CBFD_NFYB_HMF PF00808.23 RLN91026.1 - 4.2e-23 81.4 0.1 5.5e-23 81.0 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 RLN91026.1 - 1.2e-16 61.2 0.4 1.8e-16 60.7 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 RLN91026.1 - 0.0072 16.5 0.4 0.016 15.4 0.1 1.6 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) TFIID-18kDa PF02269.16 RLN91026.1 - 0.06 13.4 0.2 0.15 12.1 0.0 1.7 1 1 1 2 2 2 0 Transcription initiation factor IID, 18kD subunit CENP-X PF09415.10 RLN91026.1 - 0.072 13.4 0.6 0.18 12.1 0.1 1.9 1 1 2 3 3 3 0 CENP-S associating Centromere protein X ABC2_membrane_3 PF12698.7 RLN91027.1 - 2.8e-21 76.0 28.6 3.7e-20 72.3 28.6 2.5 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 RLN91027.1 - 0.0006 19.3 23.9 0.00067 19.1 21.0 2.2 2 0 0 2 2 2 1 ABC-2 type transporter VIT1 PF01988.19 RLN91027.1 - 5.6 6.8 8.1 1.7 8.4 4.6 1.8 2 1 0 2 2 2 0 VIT family ABC2_membrane_3 PF12698.7 RLN91028.1 - 2.9e-38 131.9 20.1 4.6e-38 131.2 20.1 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 RLN91028.1 - 1e-26 94.1 0.0 1.9e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN91028.1 - 3.3e-10 40.3 0.9 1.9e-08 34.5 0.0 2.6 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 RLN91028.1 - 0.015 16.0 0.0 6.6 7.5 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4162) AAA_15 PF13175.6 RLN91028.1 - 0.04 13.6 0.0 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF2441 PF10386.9 RLN91029.1 - 0.01 15.8 0.5 0.4 10.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2441) Glyco_hydro_7 PF00840.20 RLN91031.1 - 1.5e-199 663.2 13.7 1.8e-199 663.0 13.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CXCR4_N PF12109.8 RLN91031.1 - 2.9 8.2 6.3 8.8 6.6 6.3 1.8 1 0 0 1 1 1 0 CXCR4 Chemokine receptor N terminal PLDc_2 PF13091.6 RLN91032.1 - 1e-15 57.8 0.0 9.9e-09 35.2 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 RLN91032.1 - 0.0063 16.6 3.7 0.14 12.4 0.1 3.2 3 0 0 3 3 3 1 Phospholipase D Active site motif CTP_transf_1 PF01148.20 RLN91033.1 - 0.021 14.6 3.1 0.058 13.2 3.0 1.9 1 1 0 1 1 1 0 Cytidylyltransferase family Myosin_head PF00063.21 RLN91034.1 - 1e-218 727.9 0.0 1.3e-218 727.6 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) CH PF00307.31 RLN91034.1 - 1e-13 51.4 0.0 2.7e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 RLN91034.1 - 0.00011 22.4 0.0 0.00027 21.1 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin IQ PF00612.27 RLN91034.1 - 0.00019 21.0 12.4 0.65 9.9 2.6 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif AAA_16 PF13191.6 RLN91034.1 - 0.016 15.6 0.0 0.065 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 RLN91034.1 - 0.1 12.9 0.1 0.35 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain GpcrRhopsn4 PF10192.9 RLN91035.1 - 2.8e-34 118.7 4.9 5e-34 117.9 4.9 1.3 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 RLN91035.1 - 0.00023 20.5 7.2 0.00037 19.8 7.2 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor PhrC_PhrF PF11131.8 RLN91035.1 - 0.031 13.9 0.9 0.088 12.4 0.9 1.8 1 0 0 1 1 1 0 Rap-phr extracellular signalling Pam17 PF08566.10 RLN91035.1 - 0.09 12.6 0.5 0.35 10.7 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 DUF3742 PF12553.8 RLN91035.1 - 8.3 6.6 8.0 0.32 11.1 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) fn3 PF00041.21 RLN91036.1 - 5.1e-49 164.6 12.6 2.5e-09 37.4 0.3 9.0 8 1 0 8 8 8 7 Fibronectin type III domain Calx-beta PF03160.14 RLN91036.1 - 1.5e-10 41.1 0.8 1.7e-05 24.9 0.0 3.3 2 1 1 3 3 3 2 Calx-beta domain Pur_ac_phosph_N PF16656.5 RLN91036.1 - 3.1e-06 27.7 15.9 0.022 15.3 0.6 7.1 8 0 0 8 8 8 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 RLN91036.1 - 0.052 13.9 0.5 1.3 9.4 0.0 3.3 4 0 0 4 4 4 0 Interferon-alpha/beta receptor, fibronectin type III PKD PF00801.20 RLN91036.1 - 0.71 9.8 14.7 3.2 7.6 0.5 5.5 7 0 0 7 7 7 0 PKD domain DUF5123 PF17161.4 RLN91037.1 - 0.01 16.9 2.8 9.3 7.4 0.4 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF5123) fn3 PF00041.21 RLN91038.1 - 3.7e-15 56.0 0.0 9.4e-07 29.1 0.0 3.5 3 0 0 3 3 3 3 Fibronectin type III domain Calx-beta PF03160.14 RLN91038.1 - 1.4e-08 34.8 2.6 7.2e-07 29.3 0.8 2.3 2 0 0 2 2 2 2 Calx-beta domain fn3 PF00041.21 RLN91039.1 - 2.9e-51 171.7 1.5 4.9e-09 36.4 0.0 9.3 9 0 0 9 9 9 7 Fibronectin type III domain Calx-beta PF03160.14 RLN91039.1 - 6.4e-24 84.0 0.4 4.3e-13 49.3 0.0 2.4 2 0 0 2 2 2 2 Calx-beta domain Pur_ac_phosph_N PF16656.5 RLN91039.1 - 3.4e-08 33.9 2.4 0.38 11.3 0.0 5.6 7 0 0 7 7 7 3 Purple acid Phosphatase, N-terminal domain DUF4959 PF16323.5 RLN91039.1 - 0.01 16.2 0.4 12 6.3 0.0 4.5 4 2 0 4 4 4 0 Domain of unknown function (DUF4959) fn3_2 PF16893.5 RLN91039.1 - 0.012 15.7 0.0 0.19 11.9 0.0 3.0 3 0 0 3 3 3 0 Fibronectin type III domain SusE PF14292.6 RLN91039.1 - 0.033 14.4 1.1 2.9 8.1 0.2 4.0 3 1 1 4 4 4 0 SusE outer membrane protein DUSP PF06337.12 RLN91040.1 - 1.1e-08 35.5 0.0 8.9e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 DUSP domain F-box PF00646.33 RLN91040.1 - 0.25 11.3 2.3 5.4 7.0 0.1 2.7 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 RLN91040.1 - 0.3 11.0 2.5 1.9 8.5 0.1 3.1 3 0 0 3 3 3 0 F-box-like PAH PF02671.21 RLN91042.1 - 6.6e-35 119.0 8.7 3.8e-18 65.4 3.0 3.1 2 1 1 3 3 3 2 Paired amphipathic helix repeat LEA_4 PF02987.16 RLN91042.1 - 0.025 14.7 2.5 0.025 14.7 2.5 1.8 2 0 0 2 2 2 0 Late embryogenesis abundant protein Med28 PF11594.8 RLN91042.1 - 0.053 13.6 0.8 33 4.6 0.0 3.2 3 0 0 3 3 3 0 Mediator complex subunit 28 CHASE3 PF05227.13 RLN91042.1 - 0.97 9.3 9.2 0.025 14.5 2.2 1.9 2 0 0 2 2 2 0 CHASE3 domain FKBP_C PF00254.28 RLN91043.1 - 8.2e-29 99.8 0.0 1.8e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 RLN91043.1 - 7.9e-13 48.9 0.0 7.9e-13 48.9 0.0 2.7 2 1 0 2 2 1 1 Nucleoplasmin-like domain TFIIF_alpha PF05793.12 RLN91043.1 - 0.0095 14.6 34.8 0.012 14.2 34.8 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PI3K_1B_p101 PF10486.9 RLN91043.1 - 0.21 9.3 6.5 0.25 9.1 6.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FANCD2OS PF15124.6 RLN91043.1 - 0.72 10.1 4.9 11 6.2 4.3 2.4 2 0 0 2 2 2 0 FANCD2 opposite strand protein Nop53 PF07767.11 RLN91043.1 - 1.1 8.5 31.3 1.8 7.9 31.3 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) ECM1 PF05782.11 RLN91043.1 - 1.3 7.9 11.6 2 7.2 11.6 1.3 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) YL1 PF05764.13 RLN91043.1 - 1.9 8.5 42.8 4.4 7.3 42.9 1.5 1 1 0 1 1 1 0 YL1 nuclear protein Cyto_heme_lyase PF01265.17 RLN91043.1 - 2.6 7.6 9.8 3.9 7.0 9.8 1.2 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Hamartin PF04388.12 RLN91043.1 - 3.2 6.3 10.6 4 6.0 10.6 1.1 1 0 0 1 1 1 0 Hamartin protein DUF2981 PF11200.8 RLN91043.1 - 8.2 6.1 9.8 12 5.5 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Pkinase_Tyr PF07714.17 RLN91045.1 - 1.3e-47 162.3 0.0 1.5e-41 142.5 0.0 4.0 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 RLN91045.1 - 7.3e-45 153.4 0.0 3.3e-41 141.4 0.0 3.6 3 1 0 3 3 3 2 Protein kinase domain Pkinase_fungal PF17667.1 RLN91045.1 - 0.00039 19.3 0.0 0.00077 18.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase CH PF00307.31 RLN91046.1 - 0.0011 19.1 0.1 0.018 15.2 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain p25-alpha PF05517.12 RLN91046.1 - 0.0027 17.9 0.0 2.9 8.1 0.0 2.5 2 0 0 2 2 2 2 p25-alpha THF_DHG_CYH_C PF02882.19 RLN91047.1 - 1.3e-63 213.1 0.0 1.9e-63 212.6 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 RLN91047.1 - 1e-12 48.3 2.8 1.5e-10 41.4 0.9 2.4 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Aminotran_1_2 PF00155.21 RLN91048.1 - 9.7e-54 182.9 0.0 1.1e-53 182.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.21 RLN91049.1 - 8e-60 202.9 0.0 1.1e-59 202.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 RLN91049.1 - 2.7e-05 23.6 0.1 3.8e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 RLN91049.1 - 3.5e-05 22.9 0.0 5.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 RLN91049.1 - 9.8e-05 21.0 0.0 0.00015 20.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Flg_hook PF02120.16 RLN91049.1 - 0.002 18.0 0.0 0.033 14.1 0.0 2.9 3 0 0 3 3 3 1 Flagellar hook-length control protein FliK DegT_DnrJ_EryC1 PF01041.17 RLN91049.1 - 0.0068 15.8 0.6 0.014 14.7 0.6 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 RLN91049.1 - 0.082 11.4 0.0 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 Methionine gamma-lyase HATPase_c_5 PF14501.6 RLN91049.1 - 0.18 11.8 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 GHKL domain Hexapep PF00132.24 RLN91050.1 - 4.4e-07 29.4 1.0 0.002 17.8 0.7 3.3 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) PA PF02225.22 RLN91050.1 - 9.4e-05 22.4 0.0 0.00044 20.2 0.0 2.1 1 0 0 1 1 1 1 PA domain PDZ PF00595.24 RLN91050.1 - 0.0001 22.6 0.0 0.0027 18.0 0.0 2.6 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 RLN91050.1 - 0.00015 21.6 0.1 0.24 11.3 0.1 2.8 2 0 0 2 2 2 2 PDZ domain Hexapep_2 PF14602.6 RLN91050.1 - 0.00021 21.0 3.9 0.63 9.8 0.0 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase PDZ_2 PF13180.6 RLN91050.1 - 0.017 15.4 0.1 1.2 9.6 0.0 2.5 2 0 0 2 2 2 0 PDZ domain BRF1 PF07741.13 RLN91050.1 - 0.22 11.9 5.5 0.46 10.9 5.5 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain CAF-1_p150 PF11600.8 RLN91050.1 - 0.71 9.6 15.1 1.1 8.9 15.1 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ion_trans PF00520.31 RLN91051.1 - 4.1e-111 370.1 46.3 5.6e-49 166.6 8.9 4.2 4 0 0 4 4 4 4 Ion transport protein Ion_trans_2 PF07885.16 RLN91051.1 - 2.8e-10 40.0 1.3 2.8e-10 40.0 1.3 4.8 5 0 0 5 5 5 1 Ion channel PKD_channel PF08016.12 RLN91051.1 - 6.7e-07 28.3 36.7 4.1e-06 25.7 2.3 5.9 5 1 1 6 6 6 4 Polycystin cation channel Lig_chan PF00060.26 RLN91051.1 - 0.0055 16.6 0.2 0.0055 16.6 0.2 3.0 3 0 0 3 3 3 1 Ligand-gated ion channel EF-hand_7 PF13499.6 RLN91052.1 - 2.4e-05 24.7 0.1 5.6e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN91052.1 - 0.12 12.4 0.0 12 6.2 0.1 2.9 3 0 0 3 3 3 0 EF-hand domain Arm PF00514.23 RLN91054.1 - 0.00092 19.2 3.7 0.88 9.7 0.0 4.3 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Ribosomal_L6e PF01159.19 RLN91054.1 - 0.2 12.2 2.1 2 9.0 0.1 2.7 3 0 0 3 3 3 0 Ribosomal protein L6e HEAT_EZ PF13513.6 RLN91054.1 - 0.93 10.1 18.2 2.8 8.5 0.2 6.2 6 0 0 6 6 6 0 HEAT-like repeat Lip_A_acyltrans PF03279.13 RLN91055.1 - 2.3e-11 43.4 0.0 5.5e-11 42.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial lipid A biosynthesis acyltransferase Thioredoxin PF00085.20 RLN91056.1 - 4.3e-61 203.3 0.0 3e-30 104.3 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 RLN91056.1 - 4.5e-10 40.0 1.3 0.00073 20.0 0.3 4.0 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_6 PF13848.6 RLN91056.1 - 5.5e-08 32.9 0.0 0.003 17.5 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_3 PF13192.6 RLN91056.1 - 2e-06 27.7 0.0 0.036 14.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_7 PF13899.6 RLN91056.1 - 1.2e-05 25.4 0.0 0.062 13.5 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 RLN91056.1 - 1.4e-05 25.3 0.0 0.42 11.0 0.0 3.8 3 2 1 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 RLN91056.1 - 3.6e-05 23.3 0.0 0.16 11.3 0.0 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 RLN91056.1 - 9.5e-05 22.3 0.1 0.3 11.0 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.6 RLN91056.1 - 0.01 15.6 0.0 0.44 10.3 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin TraF PF13728.6 RLN91056.1 - 0.014 15.3 0.0 0.87 9.4 0.0 2.7 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 RLN91056.1 - 0.037 14.2 0.8 15 5.7 0.0 3.6 2 2 2 4 4 4 0 Thioredoxin DSBA PF01323.20 RLN91056.1 - 0.079 12.7 4.0 6.7 6.4 0.0 3.4 2 2 2 4 4 4 0 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 RLN91056.1 - 0.11 12.2 0.1 16 5.1 0.0 3.2 2 2 2 4 4 4 0 Thioredoxin Glutaredoxin PF00462.24 RLN91056.1 - 0.4 10.9 3.2 7.9 6.8 0.3 3.0 2 2 0 2 2 2 0 Glutaredoxin Ion_trans PF00520.31 RLN91057.1 - 1.5e-15 57.1 1.4 2e-15 56.7 1.4 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 RLN91058.1 - 1.1e-49 168.9 12.0 1e-32 113.3 5.3 2.6 2 1 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 RLN91058.1 - 0.022 13.4 18.8 0.96 8.1 1.4 4.0 3 1 1 4 4 4 0 Polycystin cation channel DUF2955 PF11168.8 RLN91058.1 - 1.2 9.0 10.2 0.58 10.0 3.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2955) Mannosyl_trans3 PF11051.8 RLN91059.1 - 1.5e-26 93.4 0.0 3.3e-25 89.0 0.0 2.1 1 1 0 1 1 1 1 Mannosyltransferase putative ABC_membrane PF00664.23 RLN91060.1 - 2.5e-28 99.5 19.2 3.1e-28 99.2 19.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region WD40 PF00400.32 RLN91061.1 - 9.8e-11 42.0 0.1 0.043 14.7 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN91061.1 - 1.8e-09 37.8 0.0 0.11 12.8 0.0 4.1 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2205 PF10224.9 RLN91061.1 - 7.3e-06 25.9 2.9 0.0017 18.3 3.3 2.3 2 0 0 2 2 2 1 Short coiled-coil protein RAB3GAP2_N PF14655.6 RLN91061.1 - 0.0062 15.9 0.0 0.077 12.2 0.0 2.1 1 1 1 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus bZIP_1 PF00170.21 RLN91061.1 - 0.014 15.5 1.7 0.098 12.8 1.5 2.3 1 1 1 2 2 2 0 bZIP transcription factor PQQ PF01011.21 RLN91061.1 - 0.015 15.2 0.4 13 6.0 0.1 3.9 4 0 0 4 4 4 0 PQQ enzyme repeat YabA PF06156.13 RLN91061.1 - 0.021 15.5 1.2 0.048 14.3 1.2 1.6 1 1 0 1 1 1 0 Initiation control protein YabA DUF812 PF05667.11 RLN91061.1 - 0.046 12.6 1.3 0.059 12.2 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) HALZ PF02183.18 RLN91061.1 - 0.047 13.9 1.6 0.36 11.1 0.4 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Prp19 PF08606.11 RLN91061.1 - 0.056 13.4 0.3 0.23 11.5 0.1 2.1 2 0 0 2 2 2 0 Prp19/Pso4-like TSC22 PF01166.18 RLN91061.1 - 0.08 13.3 0.6 0.31 11.4 0.1 2.3 2 1 1 3 3 3 0 TSC-22/dip/bun family FAD_binding_9 PF08021.11 RLN91061.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain WD40 PF00400.32 RLN91063.1 - 9.2e-12 45.3 0.1 0.04 14.8 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF4778 PF16008.5 RLN91063.1 - 0.24 11.4 9.2 0.36 10.8 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) SOBP PF15279.6 RLN91063.1 - 1.4 9.4 8.8 2.5 8.6 8.8 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Cyt-b5 PF00173.28 RLN91064.1 - 0.0099 16.0 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ank_2 PF12796.7 RLN91065.1 - 2.5e-10 40.8 0.7 2.8e-06 27.8 0.2 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN91065.1 - 2.6e-07 30.4 1.8 0.25 12.0 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 RLN91065.1 - 3.8e-05 24.2 2.0 0.45 11.2 0.4 3.4 2 2 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN91065.1 - 0.00026 21.3 4.6 0.78 10.3 0.1 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 RLN91065.1 - 0.0035 17.6 1.0 0.29 11.5 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) TauE PF01925.19 RLN91066.1 - 9.2e-24 84.4 19.6 6e-12 45.7 0.1 2.6 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE DUF3169 PF11368.8 RLN91066.1 - 0.17 11.4 1.5 5.6 6.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) TMEMspv1-c74-12 PF11044.8 RLN91066.1 - 0.55 10.3 3.4 10 6.2 0.0 2.6 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein YbhQ PF11076.8 RLN91067.1 - 0.11 12.5 0.4 0.48 10.4 0.1 2.1 2 0 0 2 2 2 0 Putative inner membrane protein YbhQ Mannosyl_trans3 PF11051.8 RLN91068.1 - 5.1e-33 114.6 0.0 1.6e-31 109.7 0.0 2.2 1 1 0 1 1 1 1 Mannosyltransferase putative Glycos_transf_2 PF00535.26 RLN91068.1 - 0.04 13.7 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Mannosyl_trans3 PF11051.8 RLN91069.1 - 1.6e-29 103.1 0.0 6e-28 98.0 0.0 2.2 1 1 0 1 1 1 1 Mannosyltransferase putative ATP-synt_F6 PF05511.11 RLN91069.1 - 0.0013 19.1 0.1 0.064 13.7 0.0 2.4 2 0 0 2 2 2 1 Mitochondrial ATP synthase coupling factor 6 Mannosyl_trans3 PF11051.8 RLN91070.1 - 8.2e-26 91.0 0.0 1.2e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Acetyltransf_3 PF13302.7 RLN91071.1 - 1.1e-08 35.9 0.0 1.7e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RLN91071.1 - 0.0035 17.6 0.0 0.0055 16.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF3265 PF11665.8 RLN91071.1 - 0.017 15.3 0.1 0.053 13.8 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3265) PAP2_C PF14360.6 RLN91072.1 - 6.4e-14 52.2 13.8 6.4e-14 52.2 13.8 3.4 4 1 0 4 4 4 1 PAP2 superfamily C-terminal WD40 PF00400.32 RLN91073.1 - 6.5e-23 80.6 7.6 2.8e-08 34.3 0.3 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN91073.1 - 1.2e-11 44.8 0.0 6.6e-05 23.1 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 RLN91073.1 - 0.57 10.2 5.2 5.5 7.0 0.1 3.6 3 1 1 4 4 4 0 WD40-like Beta Propeller Repeat DUF4345 PF14248.6 RLN91074.1 - 0.0057 16.6 4.3 0.0059 16.5 3.0 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4345) DUF1282 PF06930.12 RLN91074.1 - 0.038 13.8 1.8 0.052 13.3 1.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) EamA PF00892.20 RLN91074.1 - 0.3 11.3 5.5 0.31 11.2 2.9 1.9 1 1 1 2 2 2 0 EamA-like transporter family EMP24_GP25L PF01105.24 RLN91075.1 - 6.7e-14 52.2 0.1 7.7e-14 52.0 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD tRNA-synt_1b PF00579.25 RLN91076.1 - 2.9e-63 213.9 0.1 4.7e-52 177.1 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (W and Y) S4 PF01479.25 RLN91076.1 - 0.00016 21.3 0.0 0.0014 18.3 0.0 2.3 2 0 0 2 2 2 1 S4 domain HTH_49 PF18010.1 RLN91076.1 - 0.16 11.8 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 Cry35Ab1 HTH C-terminal domain YycH PF07435.11 RLN91076.1 - 0.19 10.6 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 YycH protein ABC_membrane PF00664.23 RLN91078.1 - 3e-17 63.2 2.7 2.9e-08 33.7 0.0 3.7 3 1 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 RLN91078.1 - 3.4e-17 63.3 0.0 2.2e-14 54.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 RLN91078.1 - 0.038 14.4 0.1 0.038 14.4 0.1 2.7 2 1 1 3 3 3 0 AAA ATPase domain MMR_HSR1 PF01926.23 RLN91078.1 - 0.073 13.2 0.0 0.66 10.1 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase DDE_Tnp_ISL3 PF01610.17 RLN91079.1 - 1.8 8.2 7.3 3.6 7.2 7.3 1.4 1 0 0 1 1 1 0 Transposase BLOC1_2 PF10046.9 RLN91079.1 - 8 6.8 12.3 0.37 11.1 1.7 3.2 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Anoctamin PF04547.12 RLN91080.1 - 3.6e-50 171.1 0.0 4.8e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel C2 PF00168.30 RLN91080.1 - 2.2e-06 27.9 0.0 4.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain HisKA_7TM PF16927.5 RLN91080.1 - 0.0084 16.2 0.3 0.0084 16.2 0.3 2.5 3 0 0 3 3 3 1 N-terminal 7TM region of histidine kinase AMP-binding PF00501.28 RLN91082.1 - 2.8e-78 263.4 0.0 4.3e-78 262.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 RLN91082.1 - 2e-65 220.5 0.0 2.9e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Thioesterase PF00975.20 RLN91082.1 - 6.4e-20 72.3 0.1 1.2e-19 71.4 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain Epimerase PF01370.21 RLN91082.1 - 8.7e-14 51.6 0.0 2e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 RLN91082.1 - 2.1e-10 41.4 0.0 6.7e-10 39.8 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 RLN91082.1 - 4.1e-09 36.7 0.2 1.6e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 RLN91082.1 - 7.8e-08 31.7 0.0 4e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Abhydrolase_6 PF12697.7 RLN91082.1 - 4.4e-06 27.5 8.3 1.6e-05 25.6 8.3 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family GDP_Man_Dehyd PF16363.5 RLN91082.1 - 1e-05 25.1 0.0 3.8e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 RLN91082.1 - 0.031 13.4 0.0 11 5.1 0.0 2.8 3 0 0 3 3 3 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RLN91082.1 - 0.037 13.2 0.0 0.063 12.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.13 RLN91082.1 - 0.045 13.3 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Abhydrolase_1 PF00561.20 RLN91082.1 - 0.1 12.2 0.3 19 4.8 0.1 2.5 1 1 0 2 2 2 0 alpha/beta hydrolase fold DUF4242 PF14026.6 RLN91082.1 - 0.11 12.7 0.0 0.37 11.0 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) Lipase_3 PF01764.25 RLN91082.1 - 0.12 12.2 0.7 0.41 10.5 0.2 2.1 2 0 0 2 2 2 0 Lipase (class 3) Sugar_tr PF00083.24 RLN91083.1 - 2e-23 83.0 13.3 2.2e-23 82.9 13.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter tRNA_NucTransf2 PF09249.11 RLN91086.1 - 0.081 13.2 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain Pkinase PF00069.25 RLN91087.1 - 1.7e-49 168.6 0.0 2.3e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN91087.1 - 3.6e-41 141.2 0.0 4.5e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN91087.1 - 0.0032 17.4 0.1 2.2 8.1 0.0 2.9 1 1 2 3 3 3 2 Phosphotransferase enzyme family DUF4328 PF14219.6 RLN91087.1 - 0.023 14.2 0.9 0.034 13.7 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) GT87 PF09594.10 RLN91087.1 - 0.063 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 87 DUF4381 PF14316.6 RLN91087.1 - 0.087 13.1 0.8 0.37 11.0 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF347 PF03988.12 RLN91087.1 - 0.1 12.8 0.1 0.1 12.8 0.1 2.0 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) LRR_4 PF12799.7 RLN91088.1 - 0.83 10.2 3.0 7.1 7.2 0.3 2.6 2 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Pkinase PF00069.25 RLN91089.1 - 4e-47 160.8 0.0 5.4e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN91089.1 - 4e-41 141.0 0.0 5.4e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 RLN91089.1 - 2.3e-08 34.2 9.7 2.8e-06 27.5 1.4 3.1 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN91089.1 - 4.1e-07 29.7 3.1 3.5e-06 26.7 1.3 2.5 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 RLN91089.1 - 0.0085 16.5 0.3 4.4 8.2 0.0 3.2 2 0 0 2 2 2 1 Leucine Rich Repeat TMEM154 PF15102.6 RLN91089.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF3377 PF11857.8 RLN91089.1 - 0.044 13.7 0.2 0.093 12.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF4448 PF14610.6 RLN91089.1 - 0.045 13.5 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DAG1 PF05454.11 RLN91089.1 - 0.078 12.3 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Pkinase_fungal PF17667.1 RLN91089.1 - 0.08 11.7 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 RLN91089.1 - 0.087 12.7 0.1 0.3 11.0 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN91089.1 - 0.14 11.1 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Doppel PF11466.8 RLN91090.1 - 0.013 15.2 6.2 0.21 11.2 2.7 2.7 2 0 0 2 2 2 0 Prion-like protein Doppel BatA PF07584.11 RLN91090.1 - 0.14 12.5 9.0 3.1 8.2 2.2 2.2 1 1 1 2 2 2 0 Aerotolerance regulator N-terminal COesterase PF00135.28 RLN91093.1 - 5e-90 302.8 0.0 6.7e-90 302.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RLN91093.1 - 2.5e-05 24.2 0.5 0.014 15.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN91093.1 - 0.63 9.5 2.6 1.5 8.3 2.6 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 RLN91094.1 - 9.1e-92 308.5 0.0 1.2e-91 308.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RLN91094.1 - 0.00015 21.7 0.5 0.00084 19.3 0.2 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN91094.1 - 0.0007 19.1 1.0 0.0013 18.3 1.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family 5_3_exonuc PF01367.20 RLN91095.1 - 0.044 14.4 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold CP12 PF02672.15 RLN91095.1 - 7.2 7.4 7.4 13 6.6 0.0 3.8 4 1 1 5 5 5 0 CP12 domain DUF5522 PF17653.1 RLN91096.1 - 2e-19 69.3 6.8 4.4e-19 68.2 6.8 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5522) Diphthami_syn_2 PF01902.17 RLN91096.1 - 1.6e-06 27.8 0.0 5.5e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Diphthamide synthase Peripla_BP_2 PF01497.18 RLN91096.1 - 2.5e-06 27.3 0.1 5.3e-05 22.9 0.1 2.2 1 1 0 1 1 1 1 Periplasmic binding protein ADIP PF11559.8 RLN91097.1 - 5.3e-05 23.4 0.4 6.6e-05 23.0 0.4 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF2353 PF09789.9 RLN91097.1 - 0.017 14.5 0.2 0.018 14.4 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) KI67R PF08065.12 RLN91097.1 - 0.019 15.5 1.4 0.024 15.2 0.4 1.7 1 1 1 2 2 2 0 KI67R (NUC007) repeat End3 PF12761.7 RLN91097.1 - 0.026 14.7 2.2 0.031 14.5 2.2 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Rtt102p PF09510.10 RLN91097.1 - 0.046 13.9 0.2 0.063 13.5 0.2 1.2 1 0 0 1 1 1 0 Rtt102p-like transcription regulator protein MA3 PF02847.17 RLN91098.1 - 1.9e-25 89.1 1.3 5.1e-25 87.6 1.3 1.8 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 RLN91098.1 - 1.1e-16 61.1 0.2 4.5e-16 59.1 0.0 2.1 3 0 0 3 3 3 1 MIF4G domain Sec23_helical PF04815.15 RLN91100.1 - 1.8e-24 85.6 0.0 3e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 RLN91100.1 - 1e-18 67.8 0.0 1.7e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_trunk PF04811.15 RLN91100.1 - 1.4e-16 60.9 0.1 2.2e-16 60.2 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Gelsolin PF00626.22 RLN91100.1 - 6.8e-09 35.5 0.0 1.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Sec23_trunk PF04811.15 RLN91101.1 - 2.2e-42 145.3 0.1 2.8e-42 145.0 0.1 1.1 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 RLN91101.1 - 2.7e-16 59.3 3.2 4.4e-16 58.7 3.2 1.3 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger MRNIP PF15749.5 RLN91101.1 - 0.016 15.9 0.2 0.025 15.3 0.2 1.3 1 0 0 1 1 1 0 MRN-interacting protein VWA_2 PF13519.6 RLN91101.1 - 0.1 13.3 0.0 1.3 9.7 0.0 2.2 1 1 0 1 1 1 0 von Willebrand factor type A domain Zn_ribbon_recom PF13408.6 RLN91101.1 - 0.32 11.6 2.6 0.56 10.8 2.6 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Anoctamin PF04547.12 RLN91102.1 - 1e-33 116.9 6.2 1.2e-33 116.6 6.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 RLN91102.1 - 1e-18 67.9 0.0 1.6e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF3938 PF13074.6 RLN91102.1 - 0.1 12.8 0.6 0.25 11.6 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) Peptidase_S28 PF05577.12 RLN91103.1 - 8.5e-77 258.8 0.0 1e-76 258.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 RLN91103.1 - 1.1e-05 24.3 0.0 1.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 RLN91103.1 - 3.5e-05 23.2 0.1 0.00038 19.8 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN91103.1 - 0.0004 20.1 0.2 0.0016 18.1 0.0 2.1 3 0 0 3 3 3 1 alpha/beta hydrolase fold DUF2920 PF11144.8 RLN91103.1 - 0.037 13.2 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Peptidase_S9 PF00326.21 RLN91103.1 - 0.068 12.6 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF4981 PF16353.5 RLN91104.1 - 0.00066 20.1 0.1 0.0049 17.3 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) PH_9 PF15410.6 RLN91104.1 - 0.014 15.8 0.3 6.6 7.1 0.1 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain PH PF00169.29 RLN91104.1 - 0.093 13.3 4.9 0.1 13.1 0.6 3.1 3 1 0 3 3 3 0 PH domain Peptidase_S28 PF05577.12 RLN91105.1 - 4.2e-80 269.7 0.3 5e-80 269.4 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 RLN91105.1 - 9.4e-06 24.5 0.0 2.7e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 RLN91105.1 - 0.00023 20.5 0.2 0.0005 19.4 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 RLN91105.1 - 0.011 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 RLN91105.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2920 PF11144.8 RLN91105.1 - 0.036 13.2 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Abhydrolase_6 PF12697.7 RLN91105.1 - 0.08 13.5 0.0 0.22 12.1 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S28 PF05577.12 RLN91106.1 - 1.8e-79 267.6 0.1 2.1e-79 267.3 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 RLN91106.1 - 9e-07 27.9 0.0 1.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 RLN91106.1 - 0.00023 20.5 0.0 0.00033 20.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN91106.1 - 0.004 16.8 0.0 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN91106.1 - 0.014 16.0 0.5 0.038 14.6 0.0 2.0 3 0 0 3 3 3 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 RLN91106.1 - 0.04 13.4 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2920 PF11144.8 RLN91106.1 - 0.042 13.0 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) UbiA PF01040.18 RLN91107.1 - 5.2e-56 189.8 19.1 7.6e-56 189.2 19.1 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family TrbC PF04956.13 RLN91107.1 - 0.018 15.2 0.7 0.018 15.2 0.7 2.7 2 1 0 2 2 2 0 TrbC/VIRB2 family NADH5_C PF06455.11 RLN91107.1 - 0.045 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus Fe_hyd_lg_C PF02906.14 RLN91108.1 - 3e-66 223.5 0.0 1.3e-64 218.2 0.0 2.2 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 RLN91108.1 - 8.6e-10 38.5 0.0 1.7e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Iron hydrogenase small subunit KIF1B PF12423.8 RLN91110.1 - 7.6e-06 26.3 0.1 7.6e-06 26.3 0.1 2.5 2 0 0 2 2 2 1 Kinesin protein 1B FHA PF00498.26 RLN91110.1 - 2.8e-05 24.4 0.0 6.4e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 RLN91110.1 - 0.17 12.2 1.0 3.3 8.0 0.3 3.2 2 1 0 2 2 2 0 FHA domain DUF1874 PF08960.10 RLN91110.1 - 7.4 6.8 6.7 8.5 6.6 1.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1874) TAF8_C PF10406.9 RLN91110.1 - 9.6 6.9 5.9 60 4.3 0.3 3.7 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term WD40 PF00400.32 RLN91111.1 - 4.8e-23 81.0 19.1 0.0052 17.6 0.1 9.8 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN91111.1 - 1.2e-10 41.6 0.9 0.01 16.1 0.1 5.6 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RLN91111.1 - 0.008 15.5 0.0 0.81 9.0 0.0 2.6 2 1 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 RLN91111.1 - 0.17 10.5 3.9 5.6 5.5 0.3 3.1 1 1 1 3 3 3 0 Nucleoporin Nup120/160 SAC3_GANP PF03399.16 RLN91112.1 - 6e-87 291.7 0.1 6e-87 291.7 0.1 2.5 4 0 0 4 4 4 1 SAC3/GANP family Ribosomal_L13e PF01294.18 RLN91113.1 - 5e-71 238.3 1.9 6.3e-71 237.9 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e BT1 PF03092.16 RLN91114.1 - 3.6e-26 91.5 13.9 2.7e-14 52.3 0.5 2.0 2 0 0 2 2 2 2 BT1 family LacY_symp PF01306.19 RLN91114.1 - 0.0024 16.7 2.5 0.0024 16.7 2.5 2.0 2 0 0 2 2 2 1 LacY proton/sugar symporter Phage_holin_1 PF04531.13 RLN91114.1 - 0.19 12.3 0.9 3.5 8.2 0.1 2.7 2 0 0 2 2 2 0 Bacteriophage holin TRAUB PF08164.12 RLN91115.1 - 1.2e-22 80.2 0.1 1.2e-22 80.2 0.1 2.6 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 RLN91115.1 - 7.4e-14 52.6 0.4 7.4e-14 52.6 0.4 3.1 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor CCDC53 PF10152.9 RLN91116.1 - 1.1e-31 110.3 24.6 4.5e-11 43.4 0.3 4.8 3 1 0 4 4 4 3 Subunit CCDC53 of WASH complex zf-MYND PF01753.18 RLN91116.1 - 9.5e-06 25.6 12.9 1.6e-05 24.9 12.9 1.4 1 0 0 1 1 1 1 MYND finger HlyD_2 PF12700.7 RLN91116.1 - 0.027 13.2 3.0 0.05 12.3 3.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein HSBP1 PF06825.12 RLN91116.1 - 0.039 13.8 0.9 0.77 9.7 0.4 3.1 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DUF2408 PF10303.9 RLN91116.1 - 1.2 9.7 5.9 0.71 10.4 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) Ank_2 PF12796.7 RLN91117.1 - 2.1e-31 108.4 4.6 2.2e-12 47.4 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN91117.1 - 4.5e-27 94.1 3.5 1.3e-11 44.7 0.1 5.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN91117.1 - 3e-24 84.4 7.6 1.9e-05 24.9 0.1 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 RLN91117.1 - 9e-24 81.0 4.6 4.5e-05 23.5 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 RLN91117.1 - 3.6e-18 65.4 4.5 1.9e-08 34.4 0.3 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) AnkUBD PF18418.1 RLN91117.1 - 0.069 13.3 0.0 0.23 11.6 0.0 1.9 1 0 0 1 1 1 0 Ankyrin ubiquitin-binding domain Axin_b-cat_bind PF08833.10 RLN91117.1 - 4.4 7.5 4.8 11 6.2 1.7 2.3 2 0 0 2 2 2 0 Axin beta-catenin binding domain ECH_1 PF00378.20 RLN91118.1 - 5.3e-34 117.7 0.0 7.9e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ACBP PF00887.19 RLN91118.1 - 4.4e-22 78.1 0.0 8.8e-22 77.1 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein ECH_2 PF16113.5 RLN91118.1 - 1.2e-21 77.6 0.1 2.8e-21 76.4 0.0 1.5 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase FYVE PF01363.21 RLN91120.1 - 2.2 8.5 9.7 4.5 7.5 9.7 1.5 1 0 0 1 1 1 0 FYVE zinc finger Abhydrolase_3 PF07859.13 RLN91121.1 - 8.2e-31 107.5 0.0 1.3e-30 106.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN91121.1 - 1.9e-11 43.5 0.0 2.6e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 RLN91121.1 - 0.012 15.0 0.0 0.075 12.5 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family BAAT_C PF08840.11 RLN91121.1 - 0.11 12.4 0.0 0.64 9.9 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Metallophos PF00149.28 RLN91122.1 - 8.4e-15 55.8 2.9 3.9e-14 53.6 2.9 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RLN91122.1 - 1e-06 29.0 0.0 1.9e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF659 PF04937.15 RLN91127.1 - 0.043 13.7 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) DBD_Tnp_Hermes PF10683.9 RLN91127.1 - 0.078 12.7 0.0 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain ATP-grasp_5 PF13549.6 RLN91127.1 - 0.19 11.1 0.1 9.5 5.6 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain zf-C3HC4_3 PF13920.6 RLN91128.1 - 0.0013 18.6 1.2 0.0013 18.6 1.2 1.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN91128.1 - 0.68 9.9 4.6 0.34 10.8 2.3 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Glyco_hydro_38N PF01074.22 RLN91129.1 - 4.7e-74 249.3 3.3 4.7e-74 249.3 3.3 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 RLN91129.1 - 1.2e-21 76.6 0.1 3.8e-21 75.0 0.1 1.9 1 0 0 1 1 1 1 Alpha mannosidase middle domain Elf4 PF07011.11 RLN91129.1 - 0.023 14.6 1.4 0.12 12.3 0.1 2.3 2 0 0 2 2 2 0 Early Flowering 4 domain Sorb PF02208.16 RLN91129.1 - 0.051 13.4 0.4 0.094 12.6 0.4 1.4 1 0 0 1 1 1 0 Sorbin homologous domain Pkinase PF00069.25 RLN91130.1 - 4.8e-64 216.3 0.0 6.3e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN91130.1 - 3e-25 89.0 0.0 4.5e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN91130.1 - 2.5e-05 23.8 0.5 9e-05 21.9 0.4 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN91130.1 - 0.0003 20.2 0.0 0.00064 19.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RLN91130.1 - 0.021 13.8 0.1 0.033 13.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 RLN91130.1 - 0.1 12.2 0.1 0.41 10.2 0.1 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 NOA36 PF06524.12 RLN91130.1 - 0.3 10.4 8.5 0.52 9.6 8.5 1.3 1 0 0 1 1 1 0 NOA36 protein Oxidored_FMN PF00724.20 RLN91131.1 - 3.7e-85 286.2 0.0 4.3e-85 286.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pkinase PF00069.25 RLN91132.1 - 7.1e-66 222.3 0.2 1.1e-65 221.7 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain PP2C PF00481.21 RLN91132.1 - 1.2e-46 159.5 0.4 2.9e-43 148.4 0.2 2.7 2 0 0 2 2 2 2 Protein phosphatase 2C Pkinase_Tyr PF07714.17 RLN91132.1 - 3.9e-39 134.5 0.2 6.9e-39 133.7 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 RLN91132.1 - 2.7e-37 126.7 0.1 1.7e-17 63.3 0.0 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 RLN91132.1 - 1.3e-06 27.9 0.0 2.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN91132.1 - 0.00033 20.6 0.0 0.72 9.7 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN91132.1 - 0.016 14.0 4.0 0.021 13.6 0.9 2.6 2 1 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 RLN91132.1 - 0.063 12.6 0.6 0.12 11.7 0.6 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sigma70_ner PF04546.13 RLN91132.1 - 1.5 8.7 6.4 35 4.2 0.0 2.7 2 0 0 2 2 2 0 Sigma-70, non-essential region RPN2_C PF18004.1 RLN91132.1 - 1.9 8.4 6.2 4.3 7.2 6.2 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain MSP1_C PF07462.11 RLN91132.1 - 8.3 5.0 7.7 0.48 9.0 1.5 2.0 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus PX PF00787.24 RLN91133.1 - 6.3e-08 32.6 0.0 1.2e-07 31.7 0.0 1.4 1 1 0 1 1 1 1 PX domain Cupin_8 PF13621.6 RLN91134.1 - 3.1e-17 63.1 0.0 4.8e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 RLN91134.1 - 0.024 14.1 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein JmjC PF02373.22 RLN91134.1 - 0.14 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase Glyco_hydro_17 PF00332.18 RLN91135.1 - 8.1e-09 35.5 0.9 3.3e-08 33.5 0.2 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 FYVE PF01363.21 RLN91136.1 - 6.3e-12 45.5 12.5 1.1e-11 44.7 12.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE PF01363.21 RLN91137.1 - 2.4e-13 50.0 13.7 7.3e-13 48.5 13.7 1.9 1 0 0 1 1 1 1 FYVE zinc finger zf-RING_2 PF13639.6 RLN91137.1 - 0.043 14.2 9.1 0.059 13.7 6.3 2.5 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 RLN91137.1 - 0.21 11.4 11.1 1 9.2 6.2 2.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN91137.1 - 0.38 10.8 6.2 0.4 10.8 3.1 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 RLN91137.1 - 2.5 8.1 8.5 31 4.5 0.1 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Utp11 PF03998.13 RLN91138.1 - 9.5e-67 225.5 22.3 1.4e-66 225.0 22.3 1.2 1 0 0 1 1 1 1 Utp11 protein Pkinase PF00069.25 RLN91138.1 - 7.9e-27 94.3 0.0 1.4e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN91138.1 - 9.3e-24 84.1 0.0 1.9e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CH PF00307.31 RLN91139.1 - 0.0024 18.0 0.0 0.0054 16.9 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain DAHP_snth_FXD PF18152.1 RLN91139.1 - 0.18 11.7 0.0 0.74 9.7 0.0 2.0 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain FYVE PF01363.21 RLN91140.1 - 6.2e-12 45.5 13.4 1.7e-11 44.1 13.4 1.8 1 0 0 1 1 1 1 FYVE zinc finger FANCI_HD1 PF14679.6 RLN91140.1 - 0.34 10.9 0.0 0.34 10.9 0.0 2.5 3 0 0 3 3 3 0 FANCI helical domain 1 C1_2 PF03107.16 RLN91140.1 - 2 8.8 9.7 1.3 9.4 5.8 2.3 2 0 0 2 2 2 0 C1 domain zf-RING_5 PF14634.6 RLN91140.1 - 2.1 8.4 13.1 7.8 6.5 13.1 2.0 1 1 0 1 1 1 0 zinc-RING finger domain IBR PF01485.21 RLN91140.1 - 5.5 7.3 9.6 8.2 6.7 5.1 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Zf_RING PF16744.5 RLN91140.1 - 8.2 6.6 13.5 66 3.7 12.7 2.4 1 1 1 2 2 2 0 KIAA1045 RING finger Spt5_N PF11942.8 RLN91141.1 - 2.1 9.4 13.2 0.38 11.8 9.1 1.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal FYVE PF01363.21 RLN91142.1 - 3.3e-10 40.0 15.8 3.3e-10 40.0 15.8 3.2 4 0 0 4 4 4 1 FYVE zinc finger zf-CRD PF17979.1 RLN91142.1 - 1.6 8.8 12.7 2.8 8.0 8.0 2.8 3 0 0 3 3 3 0 Cysteine rich domain with multizinc binding regions Zf_RING PF16744.5 RLN91142.1 - 4.9 7.3 10.1 24 5.1 10.1 2.3 1 1 0 1 1 1 0 KIAA1045 RING finger RNHCP PF12647.7 RLN91142.1 - 6.5 6.8 15.9 0.38 10.8 0.6 3.4 2 1 0 2 2 2 0 RNHCP domain FYVE PF01363.21 RLN91143.1 - 1e-11 44.8 11.7 1.9e-11 43.9 11.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger DUF1116 PF06545.11 RLN91143.1 - 0.0066 15.9 0.1 0.024 14.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1116) DUF326 PF03860.16 RLN91143.1 - 0.29 11.2 4.2 0.53 10.3 4.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF326) zf-RING_5 PF14634.6 RLN91143.1 - 0.57 10.2 5.0 1.3 9.1 2.6 2.3 2 0 0 2 2 2 0 zinc-RING finger domain C1_2 PF03107.16 RLN91143.1 - 7.5 7.0 6.9 8 6.9 3.6 2.4 2 0 0 2 2 2 0 C1 domain zf-CRD PF17979.1 RLN91143.1 - 8.8 6.4 10.8 1.2e+02 2.7 0.0 2.5 2 1 0 2 2 2 0 Cysteine rich domain with multizinc binding regions Pkinase_Tyr PF07714.17 RLN91144.1 - 1.9e-38 132.2 0.0 1.4e-29 103.2 0.0 3.5 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 RLN91144.1 - 8.7e-36 123.6 0.0 3e-26 92.4 0.0 3.4 3 1 0 3 3 3 2 Protein kinase domain Pkinase_fungal PF17667.1 RLN91144.1 - 0.00013 20.9 0.0 0.00086 18.2 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 RLN91144.1 - 0.006 16.5 0.4 0.024 14.6 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 RLN91144.1 - 0.035 13.7 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family HSF_DNA-bind PF00447.17 RLN91145.1 - 7e-22 77.9 3.0 1.4e-21 76.9 3.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding UFD1 PF03152.14 RLN91145.1 - 8.5e-13 48.1 0.0 3.3e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 DUF908 PF06012.12 RLN91145.1 - 0.15 11.5 1.1 0.22 10.9 1.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) FH2 PF02181.23 RLN91146.1 - 1.7e-45 155.7 0.7 2.1e-45 155.5 0.7 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain DUF1664 PF07889.12 RLN91146.1 - 8.1e-05 22.7 0.1 0.26 11.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Vps53_N PF04100.12 RLN91146.1 - 0.024 13.6 0.2 0.034 13.1 0.2 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal DUF4665 PF15679.5 RLN91146.1 - 0.036 14.7 0.3 0.057 14.0 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4665) HAUS-augmin3 PF14932.6 RLN91146.1 - 0.038 13.6 0.3 0.05 13.2 0.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF1043 PF06295.12 RLN91146.1 - 0.073 13.1 2.0 0.13 12.2 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Rx_N PF18052.1 RLN91146.1 - 0.092 13.0 0.6 0.18 12.1 0.6 1.5 1 1 0 1 1 1 0 Rx N-terminal domain NPV_P10 PF05531.12 RLN91146.1 - 0.096 13.2 1.8 1.8 9.1 1.8 2.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CCDC53 PF10152.9 RLN91148.1 - 5e-69 231.6 27.1 2.8e-12 47.3 0.1 7.6 7 1 0 7 7 7 6 Subunit CCDC53 of WASH complex FH2 PF02181.23 RLN91148.1 - 2.7e-22 79.4 0.0 4.4e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Formin Homology 2 Domain PHD PF00628.29 RLN91148.1 - 0.00041 20.2 6.5 0.0012 18.7 6.5 1.9 1 1 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.6 RLN91148.1 - 0.0044 17.2 0.8 0.0044 17.2 0.8 1.7 2 0 0 2 2 2 1 PHD-zinc-finger like domain Sigma70_r4 PF04545.16 RLN91148.1 - 0.0065 16.0 0.0 1.2e+02 2.3 0.0 4.8 5 0 0 5 5 5 0 Sigma-70, region 4 zf-HC5HC2H PF13771.6 RLN91148.1 - 0.019 15.2 0.4 0.019 15.2 0.4 1.7 2 0 0 2 2 2 0 PHD-like zinc-binding domain DUF2318 PF10080.9 RLN91148.1 - 0.052 13.7 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-PHD-like PF15446.6 RLN91148.1 - 0.12 12.0 6.9 0.045 13.4 2.9 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_4 PF16866.5 RLN91148.1 - 0.46 10.6 2.5 1.3 9.2 2.5 1.8 1 0 0 1 1 1 0 PHD-finger PDDEXK_3 PF13366.6 RLN91150.1 - 1.1e-30 106.4 0.0 1.7e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily HSDR_N_2 PF13588.6 RLN91150.1 - 0.039 14.0 0.0 0.12 12.3 0.0 1.8 2 1 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Tox-REase-9 PF15650.6 RLN91150.1 - 0.17 12.2 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 9 TTL PF03133.15 RLN91151.1 - 1.3e-72 244.5 0.0 2e-72 243.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RLN91151.1 - 0.00011 21.6 0.0 0.00096 18.5 0.0 2.1 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RLN91151.1 - 0.005 16.1 0.0 0.35 10.1 0.0 2.1 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp PAC1 PF16094.5 RLN91152.1 - 0.00029 20.1 0.1 0.00029 20.1 0.1 2.4 2 0 0 2 2 1 1 Proteasome assembly chaperone 4 DivIC PF04977.15 RLN91152.1 - 0.016 14.9 16.0 0.52 10.1 2.4 4.5 4 0 0 4 4 4 0 Septum formation initiator Seryl_tRNA_N PF02403.22 RLN91152.1 - 0.56 10.5 20.1 1.7 8.9 6.3 3.9 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Prominin PF05478.11 RLN91152.1 - 0.93 7.4 14.8 0.021 12.8 7.9 1.5 2 0 0 2 2 2 0 Prominin KASH_CCD PF14662.6 RLN91152.1 - 1.1 9.1 23.3 0.03 14.2 14.9 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Macoilin PF09726.9 RLN91152.1 - 1.3 7.5 19.1 0.24 9.9 14.0 2.0 2 0 0 2 2 2 0 Macoilin family GIT_CC PF16559.5 RLN91152.1 - 1.7 8.6 12.1 1.4 8.9 1.3 4.2 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Spc7 PF08317.11 RLN91152.1 - 2.3 7.0 26.6 0.47 9.3 14.4 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 RLN91152.1 - 3 8.0 14.9 0.095 12.9 1.2 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Leu_zip PF15294.6 RLN91152.1 - 5 6.6 19.6 0.27 10.7 9.6 2.7 2 1 1 3 3 3 0 Leucine zipper BLOC1_2 PF10046.9 RLN91152.1 - 7.1 7.0 15.6 0.45 10.8 0.2 3.8 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5082 PF16888.5 RLN91152.1 - 7.9 6.8 16.3 1.2 9.5 0.6 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) Golgin_A5 PF09787.9 RLN91152.1 - 9.6 5.6 30.2 0.79 9.1 3.3 3.1 2 1 1 3 3 3 0 Golgin subfamily A member 5 Elicitin PF00964.17 RLN91154.1 - 9e-16 57.8 1.7 1.4e-15 57.1 1.7 1.3 1 0 0 1 1 1 1 Elicitin SOG2 PF10428.9 RLN91154.1 - 0.024 13.9 0.5 0.024 13.9 0.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PUB PF09409.10 RLN91155.1 - 1.5e-18 66.5 0.0 4e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 PUB domain DUF4366 PF14283.6 RLN91155.1 - 0.022 14.8 1.5 0.18 11.9 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) Sugarporin_N PF11471.8 RLN91155.1 - 0.15 12.0 3.3 0.53 10.3 3.3 2.0 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension ABC2_membrane PF01061.24 RLN91156.1 - 7.8e-68 228.0 47.1 1.1e-35 123.0 18.9 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN91156.1 - 5.9e-30 104.6 0.0 1.5e-13 51.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN91156.1 - 1.2e-08 35.1 3.9 0.0021 17.9 0.0 3.8 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN91156.1 - 1.1e-06 28.7 1.9 0.0094 15.9 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 RLN91156.1 - 6e-06 25.9 5.8 0.029 14.1 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN91156.1 - 2.5e-05 24.0 1.2 0.011 15.3 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 RLN91156.1 - 3e-05 24.5 1.6 0.086 13.2 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 RLN91156.1 - 0.00011 21.8 1.0 0.5 9.8 0.0 3.9 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RLN91156.1 - 0.00054 20.5 0.9 0.067 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RLN91156.1 - 0.0012 19.2 0.5 1.5 9.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 RLN91156.1 - 0.0022 17.2 7.9 0.0022 17.2 7.9 3.2 4 0 0 4 4 4 2 ABC-2 family transporter protein AAA_18 PF13238.6 RLN91156.1 - 0.076 13.6 1.0 14 6.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 RLN91156.1 - 0.11 12.2 1.4 3 7.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RLN91156.1 - 0.15 12.0 2.4 8.3 6.3 0.0 2.7 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 RLN91156.1 - 0.16 12.1 3.4 3.7 7.7 0.2 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF815 PF05673.13 RLN91156.1 - 0.24 10.5 0.6 0.63 9.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 RLN91156.1 - 0.45 10.3 1.7 5.9 6.6 0.4 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 RLN91156.1 - 0.47 10.5 4.7 1.6 8.8 0.4 2.8 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 RLN91156.1 - 0.99 8.7 2.9 5 6.4 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 RLN91156.1 - 1.9 8.1 4.8 1.1 8.8 0.8 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Trep_Strep PF09605.10 RLN91157.1 - 0.015 15.3 1.1 0.015 15.3 1.1 1.5 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Cytadhesin_P30 PF07271.11 RLN91157.1 - 0.18 11.3 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Cytadhesin P30/P32 Holin_2-3 PF13272.6 RLN91157.1 - 0.3 11.4 4.1 0.39 11.0 0.1 2.4 2 1 0 2 2 2 0 Putative 2/3 transmembrane domain holin Myco_arth_vir_N PF09610.10 RLN91157.1 - 2.7 8.2 5.7 7.1 6.8 5.7 1.7 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) HTH_OrfB_IS605 PF12323.8 RLN91158.1 - 9.5e-11 41.0 2.5 9.5e-11 41.0 2.5 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain SNARE_assoc PF09335.11 RLN91159.1 - 1.3e-17 64.4 20.6 3.8e-17 62.9 10.0 3.1 2 1 1 3 3 3 2 SNARE associated Golgi protein FixS PF03597.15 RLN91159.1 - 2 8.2 7.7 0.79 9.5 1.1 3.1 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type DUF4229 PF14012.6 RLN91159.1 - 2 8.5 15.3 0.73 10.0 0.8 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) zf-C3HC4_2 PF13923.6 RLN91160.1 - 3.4e-11 42.8 8.9 7.6e-11 41.7 8.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN91160.1 - 2.5e-09 36.8 9.4 6.1e-09 35.6 9.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN91160.1 - 1.7e-07 31.4 8.8 4e-07 30.3 8.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RLN91160.1 - 2.1e-06 27.5 8.8 3.8e-06 26.7 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN91160.1 - 8.5e-06 25.6 8.5 1.8e-05 24.6 8.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RLN91160.1 - 6.4e-05 22.9 8.2 0.00015 21.7 8.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 RLN91160.1 - 0.001 19.2 8.4 0.0024 18.0 8.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 RLN91160.1 - 0.0017 18.6 6.9 0.0047 17.2 6.9 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 RLN91160.1 - 0.0049 16.7 3.1 0.011 15.5 3.1 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 RLN91160.1 - 0.0061 16.4 4.1 0.014 15.2 4.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 RLN91160.1 - 0.0089 15.8 6.5 0.024 14.4 6.5 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 RLN91160.1 - 0.13 12.3 3.3 0.27 11.3 3.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 RLN91160.1 - 2.2 8.1 6.4 1.5 8.6 4.4 1.9 1 1 0 1 1 1 0 RING-like zinc finger Pho88 PF10032.9 RLN91161.1 - 8.4e-17 61.0 0.0 8.7e-17 61.0 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Pkinase_Tyr PF07714.17 RLN91162.1 - 3.5e-69 233.0 0.0 2.6e-32 112.1 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 RLN91162.1 - 3.7e-64 216.6 0.0 3e-30 105.5 0.0 3.6 3 1 0 4 4 4 3 Protein kinase domain Ank_2 PF12796.7 RLN91162.1 - 5.7e-36 123.0 9.9 6.3e-13 49.1 0.8 5.1 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN91162.1 - 7.2e-29 99.8 3.2 5.2e-07 30.1 0.0 6.8 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN91162.1 - 3.4e-27 91.5 1.2 0.00068 19.9 0.0 8.8 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 RLN91162.1 - 4.1e-27 93.9 10.5 1.1e-07 32.0 0.1 5.8 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN91162.1 - 6.1e-25 86.5 5.2 0.00012 22.3 0.3 7.4 7 0 0 7 7 7 4 Ankyrin repeat APH PF01636.23 RLN91162.1 - 0.00013 22.0 3.6 0.0089 16.0 0.0 3.4 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 RLN91162.1 - 0.0013 18.1 0.0 1.6 8.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Pkinase_Tyr PF07714.17 RLN91164.1 - 1.6e-77 260.3 0.0 2.4e-36 125.4 0.0 3.9 3 1 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 RLN91164.1 - 2.8e-75 253.1 0.0 4.2e-35 121.4 0.0 4.7 5 0 0 5 5 5 3 Protein kinase domain Pkinase_fungal PF17667.1 RLN91164.1 - 1.8e-06 27.0 0.0 0.00031 19.6 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 RLN91164.1 - 6.7e-05 22.9 0.1 1.1 9.1 0.0 3.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 RLN91164.1 - 0.0014 18.0 0.1 0.62 9.4 0.1 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RLN91164.1 - 0.0037 16.9 0.1 0.95 9.0 0.0 3.0 3 0 0 3 3 3 1 RIO1 family EcKinase PF02958.20 RLN91164.1 - 0.0088 15.4 0.4 3.4 6.9 0.0 2.7 3 0 0 3 3 3 2 Ecdysteroid kinase UDPGP PF01704.18 RLN91165.1 - 2.1e-21 76.1 0.0 3e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Anoctamin PF04547.12 RLN91166.1 - 5.6e-88 295.7 12.2 7.2e-88 295.4 12.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Methyltransf_31 PF13847.6 RLN91167.1 - 1e-13 51.3 0.0 1.3e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN91167.1 - 3.3e-10 40.5 0.0 9.5e-10 39.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 RLN91167.1 - 1.6e-09 37.6 0.0 5.7e-09 35.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 RLN91167.1 - 6.1e-08 32.4 0.0 8.8e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 RLN91167.1 - 2e-06 27.7 0.0 4.5e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN91167.1 - 4.7e-06 27.2 0.0 1.2e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN91167.1 - 5.2e-06 27.1 0.0 1.1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.12 RLN91167.1 - 1.7e-05 24.4 0.0 2.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase UPF0020 PF01170.18 RLN91167.1 - 0.00027 20.7 0.0 0.0006 19.5 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmC_N PF17827.1 RLN91167.1 - 0.0066 17.0 1.0 0.033 14.8 0.0 2.7 3 1 0 3 3 3 1 PrmC N-terminal domain Methyltransf_18 PF12847.7 RLN91167.1 - 0.0086 16.0 0.0 0.022 14.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 RLN91167.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CMAS PF02353.20 RLN91167.1 - 0.047 13.0 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 RLN91167.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain DUF3995 PF13160.6 RLN91167.1 - 0.12 12.8 0.0 0.28 11.5 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) CitT PF12431.8 RLN91167.1 - 0.14 12.5 0.1 0.46 10.9 0.1 2.0 1 0 0 1 1 1 0 Transcriptional regulator Methyltransf_4 PF02390.17 RLN91167.1 - 0.15 11.5 0.0 0.42 10.1 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Eco57I PF07669.11 RLN91167.1 - 0.16 12.5 0.0 0.31 11.6 0.0 1.4 1 0 0 1 1 1 0 Eco57I restriction-modification methylase DOT1 PF08123.13 RLN91167.1 - 0.22 11.0 0.0 0.34 10.4 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 MetJ PF01340.20 RLN91168.1 - 0.07 13.1 1.0 1.2 9.1 0.1 2.8 2 1 1 3 3 3 0 Met Apo-repressor, MetJ IQ PF00612.27 RLN91168.1 - 0.89 9.5 10.7 1.3 9.0 2.5 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif PriA_CRR PF18319.1 RLN91168.1 - 2.5 8.2 9.7 4.7 7.3 0.2 2.8 3 0 0 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain Ank_4 PF13637.6 RLN91169.1 - 4.1e-14 52.8 3.2 5.5e-07 30.0 0.0 4.1 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN91169.1 - 3e-13 49.6 5.9 1.6e-05 25.2 0.0 3.9 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 RLN91169.1 - 4e-13 49.8 2.9 9.6e-11 42.1 3.8 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN91169.1 - 5.4e-09 35.6 5.2 0.014 15.8 0.0 5.3 5 1 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 RLN91169.1 - 0.00054 20.2 6.9 4.3 7.8 0.0 3.8 3 2 0 4 4 4 3 Ankyrin repeats (many copies) CAML PF14963.6 RLN91169.1 - 7.1 6.7 7.0 13 5.8 7.0 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand HALZ PF02183.18 RLN91170.1 - 0.024 14.9 13.6 0.22 11.7 2.2 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.6 RLN91170.1 - 2.5 8.3 9.7 10 6.3 0.9 3.1 2 1 0 2 2 2 0 Sperm tail C-terminal domain NAD_binding_6 PF08030.12 RLN91171.1 - 2.3e-33 115.5 0.0 1.5e-31 109.7 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 RLN91171.1 - 8.1e-20 70.9 0.0 1.7e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 RLN91171.1 - 1.1e-14 54.7 8.7 1.1e-14 54.7 8.7 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 RLN91171.1 - 0.00073 20.2 0.0 0.008 16.8 0.0 2.3 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain EF-hand_7 PF13499.6 RLN91171.1 - 0.018 15.5 1.3 0.038 14.4 1.3 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 RLN91171.1 - 0.077 13.0 0.1 0.23 11.5 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain DUF3565 PF12088.8 RLN91171.1 - 3.4 7.7 4.7 0.88 9.6 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3565) Spermine_synth PF01564.17 RLN91172.1 - 3e-66 222.4 0.1 5.7e-66 221.5 0.0 1.4 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 RLN91172.1 - 1.6e-21 75.9 0.2 4.2e-21 74.6 0.2 1.7 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 RLN91172.1 - 5.3e-05 23.8 0.1 0.00016 22.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_30 PF05430.11 RLN91172.1 - 0.004 17.0 0.0 0.0066 16.3 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.6 RLN91172.1 - 0.093 12.6 0.0 0.17 11.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Keratin_2_head PF16208.5 RLN91173.1 - 0.58 10.3 20.5 0.89 9.7 20.5 1.2 1 0 0 1 1 1 0 Keratin type II head TraT PF05818.12 RLN91173.1 - 0.77 9.4 2.1 1.2 8.8 2.1 1.4 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein zf-U1 PF06220.12 RLN91174.1 - 2.1e-19 69.0 6.3 2.7e-19 68.7 6.3 1.1 1 0 0 1 1 1 1 U1 zinc finger CLIP1_ZNF PF16641.5 RLN91174.1 - 0.048 13.5 1.5 0.067 13.1 1.5 1.2 1 0 0 1 1 1 0 CLIP1 zinc knuckle eIF-5_eIF-2B PF01873.17 RLN91176.1 - 1.9e-35 121.3 0.1 5.6e-35 119.8 0.1 1.8 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 RLN91176.1 - 1.7e-17 63.3 2.8 1.7e-17 63.3 2.8 3.0 2 1 1 3 3 1 1 eIF4-gamma/eIF5/eIF2-epsilon Zip PF02535.22 RLN91176.1 - 0.011 15.0 8.8 0.015 14.6 8.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Apt1 PF10351.9 RLN91176.1 - 0.051 12.4 12.9 0.067 12.0 12.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DDHD PF02862.17 RLN91176.1 - 0.071 13.3 3.3 0.13 12.4 3.3 1.5 1 0 0 1 1 1 0 DDHD domain NPR3 PF03666.13 RLN91176.1 - 0.34 9.7 19.0 0.46 9.2 19.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Gti1_Pac2 PF09729.9 RLN91176.1 - 0.47 10.5 12.0 0.86 9.7 12.0 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4775 PF16001.5 RLN91176.1 - 0.77 9.1 37.6 1.1 8.5 37.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) Presenilin PF01080.17 RLN91176.1 - 1.2 7.8 15.6 1.7 7.3 15.6 1.2 1 0 0 1 1 1 0 Presenilin Vfa1 PF08432.10 RLN91176.1 - 1.7 8.9 29.3 3.8 7.8 29.3 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDRGK PF09756.9 RLN91176.1 - 2.8 7.5 32.0 5.5 6.5 32.0 1.4 1 0 0 1 1 1 0 DDRGK domain ALMT PF11744.8 RLN91176.1 - 3.4 6.4 13.5 4.7 5.9 13.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Tim54 PF11711.8 RLN91176.1 - 3.5 6.3 16.4 6.2 5.5 16.4 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_S64 PF08192.11 RLN91176.1 - 4.6 5.6 12.2 6.2 5.2 12.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF2151 PF10221.9 RLN91176.1 - 5.8 5.4 16.8 8.4 4.9 16.8 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator PTPRCAP PF15713.5 RLN91176.1 - 5.8 7.2 24.9 0.44 10.8 18.4 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated MMM1 PF10296.9 RLN91176.1 - 7.3 5.5 11.0 11 4.9 11.0 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 SLC12 PF03522.15 RLN91176.1 - 8.8 5.2 17.0 12 4.7 17.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Aldedh PF00171.22 RLN91177.1 - 2.9e-188 626.1 0.2 3.4e-188 625.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NTP_transf_4 PF13562.6 RLN91177.1 - 0.033 14.4 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 Sugar nucleotidyl transferase IPI_T4 PF11634.8 RLN91177.1 - 0.035 14.1 0.1 6 6.9 0.0 2.7 2 0 0 2 2 2 0 Nuclease inhibitor from bacteriophage T4 Nucleopor_Nup85 PF07575.13 RLN91178.1 - 4.5e-68 230.2 6.8 6.9e-68 229.6 6.8 1.2 1 0 0 1 1 1 1 Nup85 Nucleoporin Mito_fiss_Elm1 PF06258.11 RLN91179.1 - 1e-70 238.3 0.1 1.3e-70 238.0 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial fission ELM1 XdhC_C PF13478.6 RLN91179.1 - 0.12 12.9 0.2 4.5 7.8 0.0 2.9 2 1 1 3 3 3 0 XdhC Rossmann domain zf-RanBP PF00641.18 RLN91180.1 - 7.7e-07 28.3 20.1 5.5e-06 25.6 5.8 2.6 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others EF-hand_7 PF13499.6 RLN91180.1 - 3.8e-06 27.2 0.5 0.76 10.3 0.1 3.8 3 0 0 3 3 3 2 EF-hand domain pair Stomoxyn PF11585.8 RLN91180.1 - 0.16 12.0 0.4 33 4.6 0.0 2.8 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn DZR PF12773.7 RLN91180.1 - 1.4 9.0 8.2 9.9 6.3 1.4 2.5 2 0 0 2 2 2 0 Double zinc ribbon Ras PF00071.22 RLN91181.1 - 3.9e-15 55.8 0.5 5.3e-15 55.4 0.5 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN91181.1 - 1.1e-05 25.6 0.1 2.1e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 RLN91181.1 - 0.02 14.9 0.1 0.032 14.3 0.1 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Skp1 PF01466.19 RLN91182.1 - 1.5e-27 95.4 0.5 1.5e-27 95.4 0.5 1.7 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 RLN91182.1 - 6.5e-19 67.9 0.3 4.8e-10 39.5 0.1 2.4 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain BTB PF00651.31 RLN91182.1 - 0.078 13.2 0.0 0.63 10.3 0.0 2.1 1 1 1 2 2 2 0 BTB/POZ domain PHD PF00628.29 RLN91183.1 - 4.5e-08 32.9 7.2 4.5e-08 32.9 7.2 2.1 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.22 RLN91183.1 - 0.005 16.7 1.0 0.005 16.7 1.0 1.8 2 0 0 2 2 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) TFIIA PF03153.13 RLN91183.1 - 0.023 14.7 17.9 0.011 15.7 15.6 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 RLN91183.1 - 0.029 13.4 8.4 0.047 12.7 8.4 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 GATA PF00320.27 RLN91183.1 - 0.054 13.1 6.4 0.19 11.4 6.4 2.0 1 0 0 1 1 1 0 GATA zinc finger DUF4604 PF15377.6 RLN91183.1 - 0.22 11.9 28.1 0.61 10.5 14.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) DUF5320 PF17253.2 RLN91183.1 - 0.73 10.9 3.8 3.7 8.7 3.8 2.3 1 0 0 1 1 1 0 Family of unknown function (DUF5320) PHD_Oberon PF07227.11 RLN91183.1 - 1.3 8.9 8.4 0.45 10.4 5.0 2.0 2 0 0 2 2 2 0 PHD - plant homeodomain finger protein zf-RING_2 PF13639.6 RLN91183.1 - 4.2 7.8 7.3 13 6.2 7.3 1.9 1 0 0 1 1 1 0 Ring finger domain Auto_anti-p27 PF06677.12 RLN91183.1 - 7.7 6.8 9.6 9.7 6.4 0.1 3.3 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) PHD_2 PF13831.6 RLN91183.1 - 9.2 5.9 8.8 0.2 11.3 1.0 2.3 3 0 0 3 3 3 0 PHD-finger Anoctamin PF04547.12 RLN91184.1 - 5.4e-123 411.2 0.5 6.6e-123 410.9 0.5 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Pkinase PF00069.25 RLN91185.1 - 2.4e-58 197.6 0.0 1.3e-57 195.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN91185.1 - 3.1e-31 108.6 0.0 2.8e-30 105.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN91185.1 - 1.6e-06 27.6 0.1 3.3e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN91185.1 - 1.7e-05 24.9 0.1 1.7e-05 24.9 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RLN91185.1 - 0.00014 21.3 0.6 0.00097 18.5 0.6 2.0 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RLN91185.1 - 0.0047 15.8 0.1 0.012 14.4 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 RLN91185.1 - 0.01 14.8 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 RLN91185.1 - 0.033 13.8 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family BT1 PF03092.16 RLN91186.1 - 4e-36 124.3 11.6 5.4e-22 77.7 1.5 2.4 2 1 0 2 2 2 2 BT1 family DegT_DnrJ_EryC1 PF01041.17 RLN91187.1 - 9.6e-28 97.5 0.0 3.4e-26 92.4 0.0 2.0 1 1 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 RLN91187.1 - 2e-06 27.0 0.0 2.7e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 RLN91187.1 - 0.00061 19.1 0.0 0.0008 18.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_72 PF03198.14 RLN91188.1 - 6.5e-113 377.1 13.3 2.3e-57 194.7 3.2 2.2 2 0 0 2 2 2 2 Glucanosyltransferase PMP22_Claudin PF00822.20 RLN91188.1 - 0.046 13.6 1.9 0.12 12.2 1.9 1.7 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family MA3 PF02847.17 RLN91189.1 - 1.8e-46 156.8 0.2 7.2e-22 77.5 0.1 2.2 2 0 0 2 2 2 2 MA3 domain Tic110 PF16940.5 RLN91190.1 - 0.01 14.4 0.0 0.016 13.7 0.0 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter Ctr PF04145.15 RLN91191.1 - 4.7e-20 72.7 0.5 7e-20 72.2 0.5 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Ctr PF04145.15 RLN91192.1 - 7.8e-14 52.5 2.2 4.2e-13 50.2 2.2 1.9 1 1 0 1 1 1 1 Ctr copper transporter family Glyco_hydro_72 PF03198.14 RLN91193.1 - 5.1e-18 65.4 0.0 5.9e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase GH115_C PF17829.1 RLN91193.1 - 0.073 12.9 0.0 0.09 12.6 0.0 1.2 1 0 0 1 1 1 0 Gylcosyl hydrolase family 115 C-terminal domain GAGA_bind PF06217.12 RLN91194.1 - 0.077 13.3 9.0 0.11 12.8 9.0 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Presenilin PF01080.17 RLN91194.1 - 1 8.1 12.7 1.2 7.8 12.7 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 RLN91194.1 - 9.5 6.0 17.4 13 5.5 17.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MPM1 PF17234.2 RLN91194.1 - 9.9 6.4 15.7 18 5.6 15.5 1.6 1 1 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Dus PF01207.17 RLN91195.1 - 3.8e-67 226.6 0.0 4.2e-66 223.2 0.0 2.1 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 RLN91195.1 - 0.00026 20.5 0.0 0.00054 19.5 0.0 1.5 1 1 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.21 RLN91195.1 - 0.00046 19.5 0.0 0.015 14.5 0.0 2.1 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase ThiG PF05690.14 RLN91195.1 - 0.00089 18.6 0.1 0.0018 17.6 0.1 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 RLN91195.1 - 0.0023 17.2 0.0 0.0048 16.1 0.0 1.4 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.17 RLN91195.1 - 0.0054 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase NMO PF03060.15 RLN91195.1 - 0.011 15.1 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase G3P_antiterm PF04309.12 RLN91195.1 - 0.022 14.1 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator FMN_dh PF01070.18 RLN91195.1 - 0.08 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase SET PF00856.28 RLN91196.1 - 2.4e-17 63.8 0.0 1.3e-16 61.4 0.0 2.4 1 1 0 1 1 1 1 SET domain Pkinase PF00069.25 RLN91196.1 - 1.7e-16 60.4 0.0 3e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain AWS PF17907.1 RLN91196.1 - 3.2e-08 33.5 2.8 7.3e-08 32.3 2.8 1.6 1 0 0 1 1 1 1 AWS domain Cyclin_N PF00134.23 RLN91196.1 - 0.0073 16.1 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Kinase-like PF14531.6 RLN91196.1 - 0.027 13.8 0.1 0.11 11.8 0.0 1.9 2 1 0 2 2 2 0 Kinase-like Glyco_hydro_72 PF03198.14 RLN91197.1 - 9e-12 44.9 0.0 1.3e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase ATG13 PF10033.9 RLN91198.1 - 1.6e-21 77.1 0.0 2.6e-15 56.8 0.0 2.4 1 1 1 2 2 2 2 Autophagy-related protein 13 Dopey_N PF04118.14 RLN91198.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Dopey, N-terminal Glyco_hydro_72 PF03198.14 RLN91199.1 - 1.2e-31 110.1 0.0 5.9e-17 61.9 0.0 2.0 1 1 1 2 2 2 2 Glucanosyltransferase GH115_C PF17829.1 RLN91199.1 - 0.0011 18.9 0.0 0.63 9.9 0.0 2.2 2 0 0 2 2 2 2 Gylcosyl hydrolase family 115 C-terminal domain UPF0149 PF03695.13 RLN91199.1 - 0.0059 16.9 0.0 4.7 7.5 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0149) Glyco_hydro_35 PF01301.19 RLN91199.1 - 0.023 14.3 0.0 7.9 6.0 0.0 2.5 2 1 0 2 2 2 0 Glycosyl hydrolases family 35 GTP_cyclohydro2 PF00925.20 RLN91199.1 - 0.12 12.0 0.0 15 5.1 0.0 2.1 2 0 0 2 2 2 0 GTP cyclohydrolase II rhaM PF05336.13 RLN91199.1 - 0.13 12.3 0.2 22 5.2 0.0 2.2 2 0 0 2 2 2 0 L-rhamnose mutarotase DUF3669 PF12417.8 RLN91199.1 - 0.14 12.4 0.1 27 5.1 0.0 2.3 2 0 0 2 2 2 0 Zinc finger protein Lactonase PF10282.9 RLN91199.1 - 0.17 11.1 0.0 14 4.8 0.0 2.1 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Pkinase_Tyr PF07714.17 RLN91200.1 - 4.9e-49 166.9 0.0 6.7e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN91200.1 - 1.3e-48 165.7 0.0 1.8e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Orthoreo_P10 PF07204.11 RLN91200.1 - 6.1e-06 26.1 0.4 2e-05 24.5 0.4 1.8 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 Mid2 PF04478.12 RLN91200.1 - 0.0031 17.4 0.3 0.0079 16.0 0.3 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Shisa PF13908.6 RLN91200.1 - 0.005 17.1 1.8 0.0061 16.8 0.1 2.0 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator DAG1 PF05454.11 RLN91200.1 - 0.031 13.7 0.1 0.055 12.8 0.1 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) TMEM51 PF15345.6 RLN91200.1 - 0.042 13.7 0.3 0.082 12.7 0.3 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 EphA2_TM PF14575.6 RLN91200.1 - 0.063 14.2 0.0 0.15 13.0 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 RLN91200.1 - 0.065 13.1 1.9 0.088 12.7 0.0 2.1 2 0 0 2 2 2 0 TMEM154 protein family Kdo PF06293.14 RLN91200.1 - 0.14 11.5 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAD_binding_6 PF00970.24 RLN91201.1 - 1.8e-22 79.6 0.0 2.9e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 RLN91201.1 - 7.6e-21 74.1 0.0 1.5e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.21 RLN91201.1 - 1.3e-14 54.8 0.0 2.3e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 RLN91201.1 - 2.1e-07 31.2 0.0 4.8e-05 23.5 0.0 2.5 2 1 1 3 3 3 2 Ferric reductase NAD binding domain GHMP_kinases_C PF08544.13 RLN91202.1 - 2e-13 50.5 0.0 2.9e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 GHMP kinases C terminal DUF4460 PF14687.6 RLN91203.1 - 0.00016 21.7 0.1 0.00068 19.7 0.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4460) OrfB_IS605 PF01385.19 RLN91203.1 - 6.4 7.0 8.5 1.6 8.9 2.8 2.2 2 0 0 2 2 2 0 Probable transposase Glyco_hydro_72 PF03198.14 RLN91204.1 - 9.4e-18 64.5 0.0 1.1e-17 64.3 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase DUF4179 PF13786.6 RLN91204.1 - 0.065 13.7 0.0 0.091 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) GH115_C PF17829.1 RLN91204.1 - 0.15 11.9 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Gylcosyl hydrolase family 115 C-terminal domain INTS5_C PF14838.6 RLN91205.1 - 1.4e-13 50.4 0.8 5e-10 38.7 0.3 2.9 3 0 0 3 3 3 2 Integrator complex subunit 5 C-terminus DUF2436 PF10365.9 RLN91205.1 - 0.026 14.3 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) Pox_A32 PF04665.12 RLN91208.1 - 2.1e-06 27.4 0.1 0.00014 21.4 0.1 2.1 1 1 0 1 1 1 1 Poxvirus A32 protein ResIII PF04851.15 RLN91208.1 - 0.0019 18.2 0.0 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF87 PF01935.17 RLN91208.1 - 0.029 14.5 0.3 0.082 13.0 0.1 1.6 1 1 0 1 1 1 0 Helicase HerA, central domain Cep57_CLD_2 PF14197.6 RLN91208.1 - 0.032 14.3 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 T2SSE PF00437.20 RLN91208.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 RLN91208.1 - 0.11 12.5 0.1 0.35 10.9 0.0 1.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DEAD PF00270.29 RLN91208.1 - 0.14 11.9 0.1 0.32 10.8 0.1 1.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase Imm3 PF14425.6 RLN91209.1 - 0.67 10.0 10.8 4.9 7.2 8.0 3.1 2 0 0 2 2 2 0 Immunity protein Imm3 DUF1488 PF07369.11 RLN91210.1 - 0.32 11.0 2.3 21 5.2 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) DinB PF05163.12 RLN91210.1 - 1.8 8.5 7.9 5.6 6.9 2.0 3.1 3 0 0 3 3 3 0 DinB family Aldo_ket_red PF00248.21 RLN91211.1 - 5.8e-33 114.3 0.0 6.4e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3715 PF12509.8 RLN91211.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3715) Trimer_CC PF08954.11 RLN91212.1 - 0.01 15.4 3.1 0.056 13.0 0.8 2.8 2 0 0 2 2 2 0 Trimerisation motif DUF3573 PF12097.8 RLN91212.1 - 0.027 13.3 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) TLE_N PF03920.15 RLN91212.1 - 0.087 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain DUF3138 PF11336.8 RLN91212.1 - 0.18 10.4 2.0 0.33 9.5 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CENP-U PF13097.6 RLN91212.1 - 2.2 8.2 8.8 0.63 10.0 4.0 2.4 1 1 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit TolA_bind_tri PF16331.5 RLN91212.1 - 2.8 8.1 7.3 0.28 11.3 1.6 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation Cnn_1N PF07989.11 RLN91212.1 - 5 7.4 8.1 7 6.9 0.3 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 betaPIX_CC PF16523.5 RLN91212.1 - 7.1 6.5 8.5 7.7 6.4 1.7 2.5 2 0 0 2 2 2 0 betaPIX coiled coil DUF5320 PF17253.2 RLN91213.1 - 1.7 9.7 10.9 0.32 12.1 0.4 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5320) Sec20 PF03908.13 RLN91213.1 - 4.8 7.2 6.2 0.83 9.6 1.4 2.1 2 0 0 2 2 2 0 Sec20 Csm1_N PF18504.1 RLN91214.1 - 6.6 7.2 9.6 10 6.5 1.6 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain WW PF00397.26 RLN91215.1 - 5e-06 26.5 1.4 9.3e-06 25.6 1.4 1.4 1 0 0 1 1 1 1 WW domain DUF3800 PF12686.7 RLN91215.1 - 0.73 10.5 5.0 1.3e+02 3.2 0.0 4.9 3 2 0 3 3 3 0 Protein of unknown function (DUF3800) TPR_12 PF13424.6 RLN91216.1 - 4.8e-11 42.8 1.5 1.3e-07 31.8 0.6 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat PH PF00169.29 RLN91216.1 - 1.1e-08 35.5 0.0 2.3e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN91216.1 - 0.0018 18.5 0.0 0.055 13.7 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain TPR_14 PF13428.6 RLN91216.1 - 0.0025 18.5 2.9 1.4 9.9 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN91216.1 - 0.003 17.4 6.5 0.1 12.5 0.3 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN91216.1 - 0.0055 16.5 0.1 2 8.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat PH_11 PF15413.6 RLN91216.1 - 0.025 15.0 0.0 0.073 13.5 0.0 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain TPR_2 PF07719.17 RLN91216.1 - 0.28 11.4 1.7 1.8 8.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 RLN91217.1 - 0.015 15.3 0.1 0.039 14.0 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Dimer_Tnp_hAT PF05699.14 RLN91217.1 - 0.031 14.1 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF4211 PF13926.6 RLN91217.1 - 0.071 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) DUF2570 PF10828.8 RLN91218.1 - 9.9e-05 22.1 5.3 9.9e-05 22.1 5.3 5.3 5 2 0 5 5 5 1 Protein of unknown function (DUF2570) eIF-6 PF01912.18 RLN91219.1 - 6.6e-81 270.4 1.3 9.2e-81 269.9 0.6 1.5 2 0 0 2 2 2 1 eIF-6 family LRR_6 PF13516.6 RLN91220.1 - 3.9e-33 110.7 54.3 0.036 14.1 0.2 18.8 19 1 0 19 19 19 10 Leucine Rich repeat LRR_4 PF12799.7 RLN91220.1 - 1.5e-30 104.7 31.2 0.00022 21.5 1.2 11.4 4 2 12 16 16 16 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN91220.1 - 2e-14 53.1 29.8 0.0009 19.0 2.5 9.1 2 2 8 12 12 12 9 Leucine rich repeat LRR_5 PF13306.6 RLN91220.1 - 8.6e-07 29.0 1.4 0.17 11.9 0.0 5.0 2 1 3 6 6 6 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 RLN91220.1 - 0.0009 19.5 33.0 30 5.7 0.1 14.3 17 1 0 17 17 17 0 Leucine Rich Repeat Phasin_2 PF09361.10 RLN91220.1 - 0.0096 16.2 5.0 12 6.3 0.0 5.1 6 0 0 6 6 6 2 Phasin protein DHFR_2 PF06442.11 RLN91220.1 - 0.013 15.3 0.1 14 5.6 0.0 3.6 4 0 0 4 4 4 0 R67 dihydrofolate reductase SAM_Ste50p PF09235.10 RLN91220.1 - 0.016 15.4 12.1 19 5.6 0.0 6.8 5 2 2 7 7 7 0 Ste50p, sterile alpha motif TfoX_C PF04994.13 RLN91220.1 - 2.6 8.2 5.5 33 4.6 0.0 4.4 5 0 0 5 5 5 0 TfoX C-terminal domain Myosin_head PF00063.21 RLN91221.1 - 4.5e-234 778.7 0.0 5.6e-234 778.3 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 RLN91221.1 - 1.1e-18 67.5 0.0 8.9e-14 51.6 0.0 2.6 2 0 0 2 2 2 2 Unconventional myosin tail, actin- and lipid-binding FYVE PF01363.21 RLN91221.1 - 1.4e-10 41.1 0.1 3.1e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger DUF1682 PF07946.14 RLN91221.1 - 0.00015 21.1 9.3 0.00031 20.1 9.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Hpr_kinase_C PF07475.12 RLN91221.1 - 0.0012 18.4 0.0 0.36 10.3 0.0 3.0 3 0 0 3 3 3 1 HPr Serine kinase C-terminal domain RsgA_GTPase PF03193.16 RLN91221.1 - 0.034 14.1 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 RLN91221.1 - 0.21 12.0 1.7 0.43 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_11 PF13086.6 RLN91221.1 - 1.5 8.6 6.4 7.3 6.3 5.3 2.1 2 0 0 2 2 2 0 AAA domain Nop53 PF07767.11 RLN91221.1 - 7.8 5.8 20.6 14 4.9 20.6 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF4064 PF13273.6 RLN91222.1 - 3.4 8.0 7.4 0.35 11.2 0.2 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) Glucan_synthase PF02364.15 RLN91223.1 - 2.4e-99 333.7 0.0 7.5e-80 269.2 0.0 2.6 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 RLN91223.1 - 7.4e-29 100.7 0.5 6.9e-28 97.6 0.5 2.3 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 SHMT PF00464.19 RLN91224.1 - 4e-199 661.2 0.0 4.7e-199 661.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 RLN91224.1 - 0.015 14.5 0.0 0.057 12.6 0.0 2.0 1 1 0 1 1 1 0 Aminotransferase class I and II FH2 PF02181.23 RLN91225.1 - 3.2e-68 230.5 0.1 3.2e-68 230.5 0.1 2.2 2 0 0 2 2 2 1 Formin Homology 2 Domain CENP-K PF11802.8 RLN91225.1 - 0.0023 17.5 0.0 0.011 15.4 0.0 2.1 2 1 0 2 2 2 1 Centromere-associated protein K ArnB_C PF18677.1 RLN91225.1 - 0.054 13.6 8.1 3.4 7.8 6.1 2.6 2 0 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain T4_Rnl2_C PF18043.1 RLN91225.1 - 0.083 13.0 0.2 2.2 8.5 0.0 2.9 2 0 0 2 2 2 0 T4 RNA ligase 2 C-terminal DUF4803 PF16061.5 RLN91225.1 - 0.19 11.1 1.7 0.34 10.3 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4803) DUF2058 PF09831.9 RLN91225.1 - 3.1 7.9 15.1 0.3 11.2 10.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Methyltransf_16 PF10294.9 RLN91226.1 - 2.7e-28 98.8 0.0 4.2e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 RLN91226.1 - 0.00043 19.8 0.2 0.00064 19.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 RLN91226.1 - 0.056 13.0 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PH PF00169.29 RLN91227.1 - 1e-12 48.5 0.1 1.2e-12 48.2 0.1 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN91227.1 - 5.1e-06 26.8 0.2 0.00035 21.0 0.2 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 RLN91227.1 - 0.00011 22.3 0.3 0.00029 21.0 0.3 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 RLN91227.1 - 0.02 14.7 0.1 0.046 13.5 0.0 1.6 1 1 1 2 2 2 0 Pleckstrin homology domain PH_9 PF15410.6 RLN91227.1 - 0.029 14.7 0.0 1.7 9.0 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain PH_3 PF14593.6 RLN91227.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.7 1 1 0 1 1 1 0 PH domain MPS2 PF17060.5 RLN91228.1 - 0.14 11.4 4.2 0.18 11.0 4.2 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF2690 PF10901.8 RLN91230.1 - 0.0012 19.1 0.7 5.6 7.3 0.0 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF2690) Bac_GH3_C PF18034.1 RLN91230.1 - 0.0051 16.6 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial Glycosyl hydrolase family 3 C-terminal domain Pox_F11 PF04943.12 RLN91230.1 - 5.1 6.1 4.9 12 4.8 0.4 2.3 2 0 0 2 2 2 0 Poxvirus F11 protein Ank_2 PF12796.7 RLN91232.1 - 3.8e-66 219.7 19.9 1.3e-13 51.3 0.6 6.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN91232.1 - 2.6e-52 174.5 14.0 1e-09 38.7 0.1 8.4 3 2 6 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN91232.1 - 1.6e-46 155.8 19.0 3.9e-07 30.2 0.3 10.7 3 2 8 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 RLN91232.1 - 1.1e-40 136.3 30.0 0.00011 22.4 0.0 12.2 12 0 0 12 12 12 9 Ankyrin repeat Ank_3 PF13606.6 RLN91232.1 - 1.2e-39 129.8 8.9 0.026 15.0 0.1 12.6 12 0 0 12 12 12 10 Ankyrin repeat Pkinase_Tyr PF07714.17 RLN91232.1 - 2.8e-19 69.4 0.0 2.1e-09 37.0 0.0 4.3 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 RLN91232.1 - 2.8e-17 63.0 0.0 8.9e-07 28.5 0.0 4.0 3 1 0 3 3 3 2 Protein kinase domain Helicase_PWI PF18149.1 RLN91232.1 - 0.12 12.6 0.4 1.6e+02 2.5 0.0 4.7 6 0 0 6 6 6 0 N-terminal helicase PWI domain Cyclin_N PF00134.23 RLN91232.1 - 0.16 11.7 5.5 12 5.7 0.1 4.1 4 1 0 4 4 4 0 Cyclin, N-terminal domain BSP_II PF05432.11 RLN91233.1 - 0.27 10.9 7.0 0.39 10.4 7.0 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Abhydro_lipase PF04083.16 RLN91236.1 - 6.2e-21 73.7 0.0 1.2e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 RLN91236.1 - 5.6e-11 42.6 0.1 1.5e-10 41.2 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN91236.1 - 0.0029 16.9 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Acyltransferase PF01553.21 RLN91238.1 - 1.8e-20 73.0 0.0 4e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase NAD_binding_4 PF07993.12 RLN91238.1 - 4.5e-15 55.5 0.0 7.1e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 RLN91238.1 - 8.4e-13 48.4 0.0 1.5e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein FLYWCH PF04500.16 RLN91239.1 - 9.4e-09 35.3 0.5 1.6e-08 34.5 0.5 1.3 1 0 0 1 1 1 1 FLYWCH zinc finger domain ABC2_membrane PF01061.24 RLN91240.1 - 2.8e-30 105.3 22.8 5e-30 104.5 22.8 1.4 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN91240.1 - 9.9e-07 28.6 0.0 3.5e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 CDR ABC transporter p450 PF00067.22 RLN91241.1 - 9.5e-44 149.9 0.1 1.2e-43 149.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC2_membrane PF01061.24 RLN91242.1 - 4.7e-69 232.0 72.4 5.2e-40 137.1 26.5 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN91242.1 - 1.3e-36 126.2 0.1 1.7e-17 64.2 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 RLN91242.1 - 1.7e-10 40.6 0.1 1.1e-07 31.7 0.0 3.0 2 0 0 2 2 2 1 CDR ABC transporter AAA_21 PF13304.6 RLN91242.1 - 1.4e-07 31.6 0.4 0.016 15.0 0.0 3.3 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN91242.1 - 4.6e-07 30.4 0.1 0.012 16.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 RLN91242.1 - 6.6e-07 29.4 1.7 0.01 15.8 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase PDR_assoc PF08370.11 RLN91242.1 - 1.3e-05 24.8 11.0 0.00063 19.4 0.3 3.5 3 0 0 3 3 2 2 Plant PDR ABC transporter associated AAA_29 PF13555.6 RLN91242.1 - 1.8e-05 24.3 6.7 0.02 14.6 1.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN91242.1 - 1.9e-05 25.0 0.1 0.082 13.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 RLN91242.1 - 3.5e-05 23.2 0.6 0.005 16.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin SMC_N PF02463.19 RLN91242.1 - 6.3e-05 22.5 0.8 0.11 11.9 0.1 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 RLN91242.1 - 0.00067 19.3 1.7 0.48 10.0 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 RLN91242.1 - 0.0027 18.2 0.0 2.2 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RLN91242.1 - 0.0036 17.7 0.1 6.3 7.2 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 RLN91242.1 - 0.0039 16.9 0.2 1.8 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 RLN91242.1 - 0.013 16.0 4.2 0.4 11.2 0.7 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 RLN91242.1 - 0.014 15.4 2.9 1.1 9.3 0.0 2.8 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_5 PF07728.14 RLN91242.1 - 0.018 15.0 0.2 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 RLN91242.1 - 0.039 13.9 2.2 7.3 6.5 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Ploopntkinase3 PF18751.1 RLN91242.1 - 0.054 13.4 0.2 0.8 9.6 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 RLN91242.1 - 0.058 13.5 0.1 12 6.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 RLN91242.1 - 0.069 13.4 0.5 7.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 RLN91242.1 - 0.08 12.8 0.0 4.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 RLN91242.1 - 0.081 13.3 0.3 11 6.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 RLN91242.1 - 0.1 12.7 3.8 2.1 8.4 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain cobW PF02492.19 RLN91242.1 - 0.14 11.8 2.7 1.9 8.1 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 RLN91242.1 - 0.19 10.8 0.5 0.54 9.4 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF815) TsaE PF02367.17 RLN91242.1 - 0.2 11.6 1.0 3.7 7.6 0.4 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 RLN91242.1 - 0.21 11.3 2.6 15 5.3 0.0 2.6 3 0 0 3 3 2 0 AAA domain ABC2_membrane_3 PF12698.7 RLN91242.1 - 0.28 10.2 57.3 0.4 9.7 28.1 3.3 2 2 0 2 2 2 0 ABC-2 family transporter protein PduV-EutP PF10662.9 RLN91242.1 - 0.45 10.2 1.7 5.4 6.7 0.4 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_ATPase PF09818.9 RLN91242.1 - 0.52 9.0 2.4 1.7 7.4 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_28 PF13521.6 RLN91242.1 - 4.3 7.6 5.6 27 5.0 0.8 3.0 3 0 0 3 3 2 0 AAA domain ATPase PF06745.13 RLN91242.1 - 7.1 5.9 5.9 10 5.4 0.2 2.9 2 1 1 3 3 3 0 KaiC ABC2_membrane PF01061.24 RLN91243.1 - 5.7e-66 221.9 64.6 6.7e-38 130.2 25.9 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN91243.1 - 3.4e-34 118.3 0.0 1.2e-15 58.2 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 RLN91243.1 - 8.5e-09 35.0 36.7 2.8e-06 26.7 23.9 4.0 3 1 0 4 4 4 2 ABC-2 family transporter protein AAA_16 PF13191.6 RLN91243.1 - 1e-07 32.5 0.2 0.0057 17.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 RLN91243.1 - 4.4e-07 29.5 1.9 0.02 14.6 0.7 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN91243.1 - 1.3e-06 28.4 0.2 0.0076 16.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 RLN91243.1 - 1.5e-06 28.3 0.0 0.1 12.4 0.0 3.5 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system PDR_CDR PF06422.12 RLN91243.1 - 3.2e-06 27.0 0.3 0.00065 19.5 0.0 3.2 3 0 0 3 3 2 1 CDR ABC transporter AAA_22 PF13401.6 RLN91243.1 - 9.6e-05 22.7 0.1 0.28 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain PDR_assoc PF08370.11 RLN91243.1 - 0.0003 20.5 13.5 0.0035 17.1 0.3 3.3 3 0 0 3 3 2 2 Plant PDR ABC transporter associated AAA_25 PF13481.6 RLN91243.1 - 0.0019 17.8 1.4 0.72 9.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 RLN91243.1 - 0.0026 17.5 0.2 1.5 8.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RLN91243.1 - 0.0031 18.1 0.7 0.4 11.1 0.3 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 RLN91243.1 - 0.0042 16.6 0.8 13 5.1 0.1 3.8 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 RLN91243.1 - 0.0049 16.2 2.7 0.15 11.3 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.29 RLN91243.1 - 0.018 15.5 0.3 13 6.2 0.0 3.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 RLN91243.1 - 0.018 14.6 1.3 1.5 8.4 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 RLN91243.1 - 0.033 14.8 0.3 10 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 RLN91243.1 - 0.054 13.6 0.4 16 5.6 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_19 PF13245.6 RLN91243.1 - 0.081 13.3 0.1 12 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF4705 PF15788.5 RLN91243.1 - 0.092 13.0 0.6 0.24 11.7 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4705) NACHT PF05729.12 RLN91243.1 - 0.13 12.2 5.1 3.8 7.4 0.2 2.6 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 RLN91243.1 - 0.18 12.0 2.4 14 5.8 0.1 2.6 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 RLN91243.1 - 0.34 11.0 3.5 8.6 6.4 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain tRNA-synt_1b PF00579.25 RLN91246.1 - 5.7e-07 29.1 0.0 7.5e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HTH_49 PF18010.1 RLN91246.1 - 0.089 12.7 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 Cry35Ab1 HTH C-terminal domain AMP-binding PF00501.28 RLN91248.1 - 1.6e-80 270.8 0.0 2.9e-80 270.0 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Aminotran_1_2 PF00155.21 RLN91248.1 - 1.2e-50 172.8 0.0 2.2e-50 171.8 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II PP-binding PF00550.25 RLN91248.1 - 5.6e-07 29.8 0.0 1.5e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Aminotran_5 PF00266.19 RLN91248.1 - 9.7e-07 28.1 0.0 1.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 RLN91248.1 - 0.0052 15.4 0.0 0.012 14.2 0.0 1.5 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 RLN91248.1 - 0.0098 14.7 0.2 0.047 12.4 0.0 2.1 2 1 0 2 2 2 1 Orn/Lys/Arg decarboxylase, major domain Dicty_REP PF05086.12 RLN91248.1 - 1.7 6.5 11.1 0.47 8.4 8.5 1.3 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein FYVE PF01363.21 RLN91249.1 - 0.00089 19.4 6.3 0.002 18.2 6.3 1.6 1 1 0 1 1 1 1 FYVE zinc finger C1_1 PF00130.22 RLN91249.1 - 0.055 13.4 2.3 0.11 12.4 2.3 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 RLN91249.1 - 0.19 11.9 3.9 0.39 10.9 3.9 1.5 1 1 0 1 1 1 0 FYVE-type zinc finger SOG2 PF10428.9 RLN91249.1 - 1.3 8.1 10.7 1.6 7.9 10.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4391 PF14335.6 RLN91250.1 - 0.024 14.3 7.8 0.28 10.8 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4391) APC_N_CC PF16689.5 RLN91250.1 - 0.051 13.7 0.8 0.18 11.9 0.8 1.9 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain Polyketide_cyc2 PF10604.9 RLN91250.1 - 0.058 13.7 2.5 0.16 12.2 0.3 2.5 2 1 1 3 3 3 0 Polyketide cyclase / dehydrase and lipid transport bZIP_1 PF00170.21 RLN91250.1 - 1.2 9.3 12.5 10 6.3 6.3 2.5 2 0 0 2 2 2 0 bZIP transcription factor RcnB PF11776.8 RLN91251.1 - 0.023 14.7 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 Nickel/cobalt transporter regulator Chorion_2 PF03964.15 RLN91252.1 - 0.06 14.2 2.8 0.074 13.9 0.9 2.1 2 0 0 2 2 2 0 Chorion family 2 bZIP_1 PF00170.21 RLN91252.1 - 1.3 9.2 10.5 12 6.1 0.3 2.5 2 0 0 2 2 2 0 bZIP transcription factor DUF4080 PF13311.6 RLN91252.1 - 1.4 9.1 5.6 1.6 8.9 4.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4080) Phage_lysis PF03245.13 RLN91254.1 - 0.018 15.2 3.8 0.028 14.6 3.8 1.4 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein DUF3168 PF11367.8 RLN91254.1 - 0.084 13.1 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3168) MethyTransf_Reg PF10119.9 RLN91255.1 - 0.25 12.1 1.9 25 5.7 0.0 2.4 2 0 0 2 2 2 0 Predicted methyltransferase regulatory domain SNF2_N PF00176.23 RLN91256.1 - 4.8e-49 166.9 0.0 1e-48 165.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN91256.1 - 7e-18 65.0 0.1 2.4e-17 63.3 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN91256.1 - 0.0017 18.3 0.0 0.0056 16.7 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 RLN91256.1 - 0.046 12.9 0.1 0.046 12.9 0.1 2.3 2 1 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase zf-C2H2_10 PF16588.5 RLN91256.1 - 3 7.7 5.9 0.34 10.7 1.5 1.7 2 0 0 2 2 2 0 C2H2 zinc-finger YabA PF06156.13 RLN91257.1 - 3.1 8.5 7.6 0.21 12.3 0.9 2.2 2 0 0 2 2 2 0 Initiation control protein YabA Glyco_hydro_61 PF03443.14 RLN91260.1 - 1.7e-07 31.4 0.0 2.4e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 RLN91260.1 - 1.5e-05 25.8 1.7 0.00012 22.8 0.2 2.5 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Tudor-knot PF11717.8 RLN91261.1 - 2.9e-05 23.9 0.2 9.3e-05 22.2 0.2 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MatE PF01554.18 RLN91262.1 - 3.2e-53 179.7 36.2 3.9e-31 107.9 13.4 2.3 2 0 0 2 2 2 2 MatE Peptidase_C48 PF02902.19 RLN91265.1 - 1.7e-11 44.4 1.8 2.1e-11 44.1 0.3 1.9 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain MULE PF10551.9 RLN91265.1 - 0.00027 21.3 1.1 0.0014 19.0 0.3 2.5 2 0 0 2 2 2 1 MULE transposase domain SWIM PF04434.17 RLN91265.1 - 0.015 15.0 0.5 0.031 13.9 0.5 1.6 1 0 0 1 1 1 0 SWIM zinc finger DDE_Tnp_ISL3 PF01610.17 RLN91265.1 - 0.052 13.3 1.4 0.15 11.8 1.4 1.7 1 0 0 1 1 1 0 Transposase GTP-bdg_N PF13167.6 RLN91265.1 - 0.14 12.9 0.0 11 6.8 0.0 2.8 2 0 0 2 2 2 0 GTP-binding GTPase N-terminal 4HBT PF03061.22 RLN91266.1 - 7.6e-07 29.4 0.0 1.4e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 RLN91266.1 - 0.05 13.2 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain 4HBT PF03061.22 RLN91267.1 - 2.1e-09 37.6 0.1 1.3e-05 25.5 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily YiiD_C PF09500.10 RLN91267.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) MaoC_dehydratas PF01575.19 RLN91267.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain DUF659 PF04937.15 RLN91268.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF 659) Ank_4 PF13637.6 RLN91270.1 - 2.8e-39 133.0 29.2 5.4e-05 23.7 0.2 11.8 5 4 8 13 13 13 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN91270.1 - 7.3e-36 121.8 29.6 0.0029 17.9 0.1 15.7 5 1 10 16 16 16 11 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN91270.1 - 1.5e-35 121.6 19.6 3e-08 34.1 0.0 7.4 3 1 6 9 9 9 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN91270.1 - 4.9e-16 57.2 14.8 7.2 7.5 0.0 14.8 16 1 1 17 17 16 2 Ankyrin repeat DUF5049 PF16468.5 RLN91270.1 - 1.2e-07 31.6 1.7 2.1 8.3 0.0 9.1 8 3 5 13 13 13 1 Domain of unknown function (DUF5049) Ank PF00023.30 RLN91270.1 - 3.9e-06 27.0 6.1 31 5.2 0.1 10.5 6 3 2 8 8 8 0 Ankyrin repeat DUF1979 PF09322.10 RLN91270.1 - 0.00011 22.0 2.3 0.7 9.8 0.0 5.9 6 1 1 7 7 7 1 Domain of unknown function (DUF1979) DUF3322 PF11795.8 RLN91270.1 - 0.0016 18.5 3.7 6.9 6.6 0.0 5.8 7 1 0 7 7 7 1 Uncharacterized protein conserved in bacteria N-term (DUF3322) DUF190 PF02641.15 RLN91270.1 - 0.12 12.7 0.2 12 6.3 0.0 3.7 3 1 0 3 3 3 0 Uncharacterized ACR, COG1993 Baculo_LEF5_C PF11792.8 RLN91270.1 - 0.13 12.0 4.3 67 3.3 0.0 4.4 3 1 1 4 4 4 0 Baculoviridae late expression factor 5 C-terminal domain TGBp3 PF02495.17 RLN91270.1 - 0.48 10.1 9.4 2e+02 1.8 0.0 6.9 9 0 0 9 9 9 0 Triple gene block 3 Fascin PF06268.13 RLN91271.1 - 0.029 14.6 0.2 0.43 10.8 0.0 2.3 2 0 0 2 2 2 0 Fascin domain DUF179 PF02622.15 RLN91272.1 - 3.7e-22 79.0 0.0 5.1e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 MutS_V PF00488.21 RLN91273.1 - 7.7e-32 110.8 0.2 1.8e-31 109.6 0.0 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 RLN91273.1 - 0.013 15.7 0.1 0.024 14.8 0.1 1.5 1 0 0 1 1 1 0 MutS domain III Type_ISP_C PF18135.1 RLN91273.1 - 0.015 14.3 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Type ISP C-terminal specificity domain DUF1989 PF09347.10 RLN91273.1 - 0.097 12.3 0.5 0.21 11.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1989) DOT1 PF08123.13 RLN91275.1 - 1.4e-05 24.8 0.0 3.4e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Histone methylation protein DOT1 CMAS PF02353.20 RLN91275.1 - 0.00018 20.9 0.0 0.00022 20.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.18 RLN91275.1 - 0.0012 18.6 0.1 0.0023 17.7 0.1 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PCMT PF01135.19 RLN91275.1 - 0.0019 18.0 0.3 0.006 16.4 0.3 1.9 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 RLN91275.1 - 0.0049 16.7 0.0 0.0067 16.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN91275.1 - 0.0057 17.3 1.2 0.05 14.3 0.8 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN91275.1 - 0.011 15.6 0.0 0.017 14.9 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain IQ PF00612.27 RLN91275.1 - 0.021 14.6 0.1 0.051 13.4 0.1 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Methyltransf_11 PF08241.12 RLN91276.1 - 6.4e-11 42.8 0.0 3e-10 40.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN91276.1 - 3.6e-09 37.2 0.0 6.5e-08 33.2 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN91276.1 - 7.2e-08 32.4 0.0 1.4e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN91276.1 - 3e-06 27.1 0.0 1.2e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN91276.1 - 0.00022 21.9 0.0 0.0057 17.4 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Helitron_like_N PF14214.6 RLN91278.1 - 5e-11 43.2 0.1 5e-11 43.2 0.1 2.4 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus TPR_MLP1_2 PF07926.12 RLN91279.1 - 0.00087 19.4 5.8 0.0016 18.5 5.6 1.4 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein CCDC144C PF14915.6 RLN91279.1 - 0.0014 17.8 0.8 0.0017 17.5 0.8 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region HrpB7 PF09486.10 RLN91279.1 - 0.0028 18.0 1.8 0.0035 17.7 1.8 1.1 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) Spc7 PF08317.11 RLN91279.1 - 0.0034 16.3 3.6 0.004 16.1 3.6 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4201 PF13870.6 RLN91279.1 - 0.0054 16.5 2.1 0.011 15.5 2.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) ATG16 PF08614.11 RLN91279.1 - 0.0058 16.9 3.2 0.0069 16.6 3.2 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) SlyX PF04102.12 RLN91279.1 - 0.0065 17.1 4.2 0.021 15.4 0.9 2.2 1 1 1 2 2 2 1 SlyX Atg14 PF10186.9 RLN91279.1 - 0.009 15.1 3.3 0.011 14.9 3.3 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Troponin PF00992.20 RLN91279.1 - 0.01 16.1 1.3 0.015 15.6 1.3 1.3 1 1 0 1 1 1 0 Troponin YscO PF07321.12 RLN91279.1 - 0.011 15.7 1.6 0.015 15.2 1.6 1.1 1 0 0 1 1 1 0 Type III secretion protein YscO BRE1 PF08647.11 RLN91279.1 - 0.017 15.2 0.4 0.022 14.8 0.4 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Cnn_1N PF07989.11 RLN91279.1 - 0.021 15.0 5.0 0.21 11.7 1.1 2.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF3450 PF11932.8 RLN91279.1 - 0.026 13.8 0.5 0.03 13.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MPS2 PF17060.5 RLN91279.1 - 0.027 13.8 1.2 0.03 13.6 1.2 1.0 1 0 0 1 1 1 0 Monopolar spindle protein 2 Laminin_II PF06009.12 RLN91279.1 - 0.027 14.5 1.0 0.036 14.1 1.0 1.2 1 0 0 1 1 1 0 Laminin Domain II Phage_GP20 PF06810.11 RLN91279.1 - 0.028 14.2 0.7 0.037 13.8 0.7 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 KI67R PF08065.12 RLN91279.1 - 0.032 14.8 2.5 0.052 14.1 2.5 1.5 1 1 0 1 1 1 0 KI67R (NUC007) repeat BST2 PF16716.5 RLN91279.1 - 0.037 14.6 1.8 0.05 14.2 1.8 1.3 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 EzrA PF06160.12 RLN91279.1 - 0.039 12.1 1.1 0.047 11.9 1.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TolA_bind_tri PF16331.5 RLN91279.1 - 0.041 14.0 3.7 0.41 10.7 2.8 2.1 1 1 1 2 2 2 0 TolA binding protein trimerisation Ran-binding PF05508.11 RLN91279.1 - 0.042 12.8 0.3 0.049 12.6 0.3 1.0 1 0 0 1 1 1 0 RanGTP-binding protein YabA PF06156.13 RLN91279.1 - 0.08 13.6 3.7 0.32 11.6 0.7 2.0 1 1 1 2 2 2 0 Initiation control protein YabA DUF4472 PF14739.6 RLN91279.1 - 0.093 13.5 3.4 0.12 13.1 3.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) Gp58 PF07902.11 RLN91279.1 - 0.096 11.0 0.7 0.11 10.8 0.7 1.0 1 0 0 1 1 1 0 gp58-like protein DASH_Dam1 PF08653.10 RLN91279.1 - 0.1 12.4 1.7 0.24 11.2 0.4 1.9 2 0 0 2 2 2 0 DASH complex subunit Dam1 Csm1_N PF18504.1 RLN91279.1 - 0.1 12.9 5.5 2.9 8.3 1.6 2.2 1 1 1 2 2 2 0 Csm1 N-terminal domain LPP PF04728.13 RLN91279.1 - 0.12 12.8 1.8 4.6 7.7 0.1 2.2 1 1 1 2 2 2 0 Lipoprotein leucine-zipper ADIP PF11559.8 RLN91279.1 - 0.13 12.3 4.7 0.36 10.9 4.6 1.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 RLN91279.1 - 0.15 11.9 4.8 0.68 9.7 0.8 2.1 1 1 1 2 2 2 0 Septum formation initiator GAS PF13851.6 RLN91279.1 - 0.21 10.9 4.4 0.33 10.3 4.3 1.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 RLN91279.1 - 0.22 12.1 5.3 0.3 11.6 5.3 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 RLN91279.1 - 0.25 11.8 6.9 0.39 11.2 3.0 2.1 1 1 1 2 2 2 0 Cell division protein ZapB Spc24 PF08286.11 RLN91279.1 - 0.85 9.9 5.1 3 8.1 1.2 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 MULE PF10551.9 RLN91280.1 - 3.9e-14 52.8 0.7 1.2e-13 51.3 0.7 1.8 1 0 0 1 1 1 1 MULE transposase domain DUF5575 PF17738.1 RLN91280.1 - 9.2e-06 24.9 0.1 1.5e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5575) Peptidase_C48 PF02902.19 RLN91280.1 - 0.00049 20.0 0.1 0.0027 17.6 0.1 2.3 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C5 PF00770.18 RLN91280.1 - 0.0055 16.4 0.1 0.013 15.1 0.1 1.6 1 0 0 1 1 1 1 Adenovirus endoprotease DDE_Tnp_ISL3 PF01610.17 RLN91280.1 - 0.009 15.7 0.8 0.009 15.7 0.8 2.6 4 0 0 4 4 4 1 Transposase ubiquitin PF00240.23 RLN91281.1 - 1.4e-11 44.0 0.1 5.5e-11 42.1 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 RLN91281.1 - 1.3e-07 31.7 0.0 2.5e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 RLN91281.1 - 2.2e-05 24.2 0.0 4.1e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 RLN91281.1 - 2.2e-05 25.0 0.0 0.00017 22.2 0.0 2.2 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukD DUF2407 PF10302.9 RLN91281.1 - 0.0015 19.0 0.0 0.0037 17.8 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ANAPC3 PF12895.7 RLN91282.1 - 0.00094 19.4 1.7 0.13 12.5 0.2 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Amino_oxidase PF01593.24 RLN91283.1 - 2.7e-18 66.5 0.0 8.7e-10 38.5 0.0 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RLN91283.1 - 2e-15 56.8 0.0 5.4e-15 55.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RLN91283.1 - 1.1e-09 38.4 0.5 2.5e-06 27.3 0.8 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RLN91283.1 - 2.5e-09 36.8 0.5 1.5e-05 24.4 0.3 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RLN91283.1 - 3.3e-07 30.0 0.3 6.6e-07 29.0 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 RLN91283.1 - 3.3e-06 26.1 0.6 0.0057 15.4 0.5 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 RLN91283.1 - 6.9e-06 25.4 0.7 1.3e-05 24.4 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 RLN91283.1 - 8.6e-06 25.8 0.0 0.17 11.9 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding MCRA PF06100.11 RLN91283.1 - 0.00021 20.2 0.1 0.00037 19.4 0.1 1.4 1 0 0 1 1 1 1 MCRA family GIDA PF01134.22 RLN91283.1 - 0.00055 19.1 0.9 0.0039 16.3 0.4 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 RLN91283.1 - 0.001 18.4 0.1 0.14 11.3 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 RLN91283.1 - 0.0014 17.9 0.3 0.0021 17.3 0.3 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 RLN91283.1 - 0.016 15.7 1.8 0.28 11.8 0.8 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RLN91283.1 - 0.025 13.6 4.9 0.87 8.6 0.1 3.0 2 1 1 3 3 3 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 RLN91283.1 - 0.12 11.6 0.8 0.21 10.8 0.8 1.4 1 0 0 1 1 1 0 FAD binding domain EF-hand_7 PF13499.6 RLN91285.1 - 1.4e-17 63.9 2.2 9.6e-09 35.6 0.2 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN91285.1 - 2.3e-15 54.9 3.6 0.0021 17.5 0.0 5.1 5 0 0 5 5 5 3 EF hand SHR-BD PF06650.12 RLN91285.1 - 5.4e-15 55.5 0.0 2.2e-13 50.2 0.0 3.5 3 1 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 EF-hand_6 PF13405.6 RLN91285.1 - 1e-14 53.1 0.7 0.013 15.4 0.0 5.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 RLN91285.1 - 6.5e-07 28.6 12.7 0.089 12.3 0.0 4.8 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 RLN91285.1 - 2.2e-05 24.2 4.6 0.12 12.2 0.0 4.3 4 0 0 4 4 4 2 EF-hand domain pair Apt1 PF10351.9 RLN91285.1 - 0.00016 20.7 0.0 0.00016 20.7 0.0 2.7 3 0 0 3 3 3 1 Golgi-body localisation protein domain EF-hand_4 PF12763.7 RLN91285.1 - 0.008 16.1 0.2 1.6 8.7 0.1 2.9 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RLN91285.1 - 0.42 10.9 2.1 2.1 8.7 0.1 3.0 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region LRR_4 PF12799.7 RLN91286.1 - 2.9e-12 46.6 18.0 9.8e-06 25.8 1.9 3.6 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN91286.1 - 1.9e-11 43.8 2.9 2.3e-08 33.7 0.5 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 RLN91286.1 - 3.6e-11 42.6 38.1 5e-06 26.2 8.5 3.2 1 1 3 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 RLN91286.1 - 0.12 12.5 12.3 11 6.4 0.1 5.7 6 0 0 6 6 6 0 Leucine Rich repeat TPR_1 PF00515.28 RLN91287.1 - 1.1e-17 62.9 6.9 6.3e-09 35.3 0.3 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN91287.1 - 9.2e-17 59.7 6.7 6.4e-09 35.3 0.4 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN91287.1 - 9.1e-15 54.1 6.0 5.7e-06 25.9 0.1 3.1 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 RLN91287.1 - 1.3e-14 53.1 4.3 6.5e-07 29.1 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN91287.1 - 2.1e-10 39.9 3.0 5.7e-05 22.9 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 RLN91287.1 - 5.7e-10 39.7 2.3 7.4e-07 29.7 0.4 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN91287.1 - 6.8e-10 38.9 2.2 0.0011 19.6 0.2 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 RLN91287.1 - 6.7e-08 32.7 3.8 0.00024 21.4 0.3 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN91287.1 - 8.1e-08 32.7 0.4 6.9e-05 23.3 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN91287.1 - 3.3e-06 27.1 0.8 1.7e-05 24.9 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN91287.1 - 1.7e-05 24.9 4.8 0.0014 18.9 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN91287.1 - 4.6e-05 23.1 2.7 0.0016 18.3 0.4 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 RLN91287.1 - 0.00025 21.0 1.0 0.16 12.1 0.0 3.2 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 RLN91287.1 - 0.00046 20.6 0.4 3 8.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN91287.1 - 0.098 12.7 0.5 0.44 10.6 0.1 2.2 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat DDE_3 PF13358.6 RLN91288.1 - 5.4e-13 48.9 0.0 3.8e-12 46.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease DNA_pol_E_B PF04042.16 RLN91289.1 - 0.08 12.3 0.4 0.11 11.8 0.4 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B zf-TRM13_CCCH PF11722.8 RLN91289.1 - 0.11 12.2 0.5 1.7 8.5 0.3 2.2 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein DNA_pol_E_B PF04042.16 RLN91290.1 - 6.8e-07 28.8 0.5 0.0066 15.8 0.1 2.5 1 1 1 2 2 2 2 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 RLN91290.1 - 0.0017 18.4 0.1 0.0023 18.0 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Hist_deacetyl PF00850.19 RLN91293.1 - 3.6e-12 46.4 0.0 4.4e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain TPR_1 PF00515.28 RLN91294.1 - 3e-25 87.0 9.7 0.0013 18.4 1.3 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat DnaJ PF00226.31 RLN91294.1 - 3.7e-21 75.0 0.8 8.1e-21 73.9 0.8 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 RLN91294.1 - 5.4e-19 66.7 14.6 0.013 15.6 0.1 7.9 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 RLN91294.1 - 6.5e-13 49.0 17.7 8.8e-06 26.1 0.6 6.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 RLN91294.1 - 3.7e-10 39.7 10.5 0.14 13.1 0.1 7.1 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN91294.1 - 1.3e-08 35.0 18.0 0.022 15.0 4.4 5.9 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 RLN91294.1 - 8.7e-08 31.8 7.0 3.5 8.1 0.0 6.3 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN91294.1 - 9.9e-07 28.4 15.9 1.3 9.2 0.0 6.9 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN91294.1 - 1.6e-05 24.5 8.6 0.0013 18.4 0.2 5.1 6 0 0 6 6 6 2 TPR repeat MIT PF04212.18 RLN91294.1 - 2.7e-05 24.1 13.2 0.00018 21.5 1.3 4.3 3 1 1 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 RLN91294.1 - 0.00016 22.3 26.9 0.00085 19.9 2.7 6.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN91294.1 - 0.00017 21.6 11.7 0.00025 21.1 2.7 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN91294.1 - 0.00035 21.0 11.2 0.0071 16.9 0.1 5.7 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN91294.1 - 0.00063 19.9 1.0 0.39 11.2 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN91294.1 - 0.0015 18.3 11.3 0.13 12.1 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Cyclin_C_2 PF16899.5 RLN91294.1 - 0.0037 17.6 2.8 0.043 14.2 0.4 2.8 2 1 1 3 3 3 1 Cyclin C-terminal domain ANAPC3 PF12895.7 RLN91294.1 - 0.0084 16.3 10.2 0.62 10.3 4.9 4.5 4 1 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 RLN91294.1 - 0.052 13.6 5.5 0.063 13.3 0.8 3.4 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) RPN7 PF10602.9 RLN91294.1 - 0.36 10.5 5.9 0.45 10.2 0.3 3.2 2 1 1 3 3 3 0 26S proteasome subunit RPN7 SHNi-TPR PF10516.9 RLN91294.1 - 0.91 9.0 4.9 33 4.0 0.1 3.8 3 0 0 3 3 3 0 SHNi-TPR Sacchrp_dh_NADP PF03435.18 RLN91295.1 - 2.3e-15 57.0 0.1 7.9e-15 55.3 0.1 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DSPc PF00782.20 RLN91296.1 - 2.9e-17 62.7 0.0 3.6e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RLN91296.1 - 0.002 18.2 0.0 0.003 17.7 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 RLN91296.1 - 0.012 15.2 0.1 0.038 13.7 0.0 1.8 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.12 RLN91296.1 - 0.021 15.1 0.0 0.03 14.6 0.0 1.2 1 0 0 1 1 1 0 Rit1 DUSP-like domain Rhodanese PF00581.20 RLN91296.1 - 0.056 14.0 0.0 0.091 13.3 0.0 1.4 1 0 0 1 1 1 0 Rhodanese-like domain Y_phosphatase PF00102.27 RLN91296.1 - 0.093 12.3 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase MRG PF05712.13 RLN91297.1 - 7.5e-40 136.3 3.0 1.8e-32 112.2 0.1 3.3 3 1 0 3 3 3 2 MRG Tudor-knot PF11717.8 RLN91297.1 - 2e-08 34.0 0.5 4.5e-08 32.9 0.5 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain N36 PF11438.8 RLN91297.1 - 0.095 12.5 4.0 0.46 10.3 4.0 2.3 1 0 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) ECH_2 PF16113.5 RLN91297.1 - 0.31 10.5 5.4 0.73 9.3 5.4 1.5 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase FUSC PF04632.12 RLN91297.1 - 6.6 5.1 8.3 10 4.5 8.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family ABC_membrane PF00664.23 RLN91298.1 - 5e-60 203.5 34.8 8.9e-37 127.2 6.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN91298.1 - 2.4e-19 70.2 2.5 4.8e-18 66.0 0.0 2.9 3 0 0 3 3 3 1 ABC transporter Dynamin_N PF00350.23 RLN91298.1 - 0.0029 17.7 0.2 0.0056 16.8 0.2 1.4 1 0 0 1 1 1 1 Dynamin family AAA_21 PF13304.6 RLN91298.1 - 0.0058 16.5 0.1 1.7 8.4 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN91298.1 - 0.0079 16.1 0.3 0.11 12.4 0.2 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 RLN91298.1 - 0.033 14.3 0.2 0.084 13.0 0.2 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 RLN91298.1 - 0.034 13.7 2.5 0.077 12.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 RLN91298.1 - 0.044 14.2 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 RLN91298.1 - 0.065 12.7 0.2 4 6.8 0.1 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RLN91298.1 - 0.065 13.0 0.2 0.14 11.9 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 RLN91299.1 - 0.13 11.7 0.7 0.15 11.5 0.7 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain zf-BED PF02892.15 RLN91300.1 - 9.7e-06 25.5 0.6 2.1e-05 24.5 0.1 1.8 2 0 0 2 2 2 1 BED zinc finger Transpos_assoc PF13963.6 RLN91300.1 - 0.037 14.3 0.1 0.081 13.3 0.1 1.5 1 0 0 1 1 1 0 Transposase-associated domain zf-C2H2_4 PF13894.6 RLN91300.1 - 0.16 12.9 0.9 0.67 11.0 0.2 2.4 1 1 1 2 2 2 0 C2H2-type zinc finger JmjC PF02373.22 RLN91301.1 - 2.3e-40 137.6 0.1 4.3e-40 136.7 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.16 RLN91301.1 - 3.8e-12 46.4 7.5 3.8e-12 46.4 7.5 1.9 2 0 0 2 2 2 1 C5HC2 zinc finger DUF2181 PF10223.9 RLN91302.1 - 1.8e-43 148.8 0.1 2.7e-43 148.2 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) Pyridoxal_deC PF00282.19 RLN91303.1 - 2.4e-76 256.9 0.0 3.5e-76 256.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Myb_DNA-binding PF00249.31 RLN91304.1 - 2.1e-28 98.2 8.9 6.1e-15 55.1 1.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN91304.1 - 3e-21 75.4 2.4 1.8e-13 50.5 0.2 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN91304.1 - 6.1e-07 29.2 0.9 0.0005 19.9 0.1 2.6 1 1 1 2 2 2 2 Myb DNA-binding like SWIM PF04434.17 RLN91304.1 - 6.5e-07 28.9 0.7 1.5e-06 27.8 0.7 1.5 1 0 0 1 1 1 1 SWIM zinc finger MULE PF10551.9 RLN91304.1 - 7.2e-05 23.1 0.0 0.00017 21.9 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain SLIDE PF09111.10 RLN91304.1 - 0.048 13.7 0.4 0.2 11.7 0.1 2.0 2 0 0 2 2 2 0 SLIDE SANT_DAMP1_like PF16282.5 RLN91304.1 - 0.19 12.0 1.1 6.3 7.1 0.2 2.5 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 RRP14 PF15459.6 RLN91304.1 - 0.72 10.5 8.5 3.5 8.3 0.6 3.1 2 1 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 JmjN PF02375.17 RLN91305.1 - 6.1e-16 58.1 0.3 1.1e-15 57.3 0.3 1.4 1 0 0 1 1 1 1 jmjN domain DUF3325 PF11804.8 RLN91306.1 - 0.1 12.8 4.6 0.054 13.7 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) Aa_trans PF01490.18 RLN91306.1 - 0.6 8.8 2.5 0.86 8.2 2.5 1.1 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein Abhydrolase_2 PF02230.16 RLN91307.1 - 3.1e-13 50.0 0.0 1.4e-08 34.8 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.13 RLN91307.1 - 0.0001 22.0 0.0 0.00021 21.0 0.0 1.4 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 RLN91307.1 - 0.00029 20.2 0.2 0.0044 16.3 0.2 2.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 JIP_LZII PF16471.5 RLN91308.1 - 0.03 14.5 0.4 0.03 14.5 0.4 2.4 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II VPS28 PF03997.12 RLN91309.1 - 1e-67 227.5 0.1 1.2e-67 227.3 0.1 1.1 1 0 0 1 1 1 1 VPS28 protein MCC-bdg_PDZ PF10506.9 RLN91309.1 - 0.0049 16.9 0.1 1.8 8.6 0.0 2.5 2 0 0 2 2 2 2 PDZ domain of MCC-2 bdg protein for Usher syndrome SHOCT PF09851.9 RLN91309.1 - 0.085 12.6 3.3 0.72 9.7 0.1 2.7 3 0 0 3 3 3 0 Short C-terminal domain MOSC PF03473.17 RLN91310.1 - 1.4e-27 96.3 0.0 8.2e-26 90.6 0.0 2.6 2 0 0 2 2 2 1 MOSC domain Aminotran_5 PF00266.19 RLN91310.1 - 2.5e-22 79.4 0.0 9.7e-15 54.4 0.0 3.2 3 0 0 3 3 3 3 Aminotransferase class-V MOSC_N PF03476.16 RLN91310.1 - 2.7e-15 56.3 0.0 2.4e-14 53.2 0.0 2.2 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MCM PF00493.23 RLN91311.1 - 1.9e-93 311.7 0.0 1.8e-82 275.8 0.0 2.2 2 0 0 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 RLN91311.1 - 1.8e-37 128.0 0.1 3.9e-37 126.9 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RLN91311.1 - 5.2e-27 94.1 1.8 1.8e-26 92.4 1.8 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 RLN91311.1 - 5.7e-11 42.9 0.1 2.2e-10 41.0 0.1 2.1 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 RLN91311.1 - 7.5e-08 32.5 0.0 1.9e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 RLN91311.1 - 1.4e-06 27.9 0.1 0.00014 21.3 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 RLN91311.1 - 0.00061 19.5 0.0 0.0089 15.7 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 RLN91311.1 - 0.0014 18.5 0.0 0.0042 16.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DDE_Tnp_2 PF04693.12 RLN91311.1 - 0.0075 15.5 0.1 0.021 14.0 0.0 1.7 2 0 0 2 2 2 1 Archaeal putative transposase ISC1217 Mg_chelatase_C PF13335.6 RLN91311.1 - 0.021 15.4 6.6 0.032 14.8 1.9 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal zf-HC5HC2H PF13771.6 RLN91311.1 - 0.034 14.4 0.3 0.075 13.3 0.3 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 RLN91311.1 - 0.11 12.6 0.2 0.23 11.6 0.2 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain AAA_22 PF13401.6 RLN91311.1 - 0.18 12.1 3.6 3.4 7.9 0.4 3.1 3 1 1 4 4 4 0 AAA domain zf-CHY PF05495.12 RLN91311.1 - 0.65 10.5 2.5 1.4 9.5 2.5 1.5 1 0 0 1 1 1 0 CHY zinc finger NIF PF03031.18 RLN91312.1 - 8.9e-23 80.8 0.5 2.3e-14 53.4 0.2 2.4 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase Lge1 PF11488.8 RLN91313.1 - 0.13 12.5 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 adh_short PF00106.25 RLN91314.1 - 1.8e-30 105.8 0.0 2.2e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN91314.1 - 2e-19 70.1 0.0 2.4e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 RLN91314.1 - 0.00013 21.5 0.1 0.012 15.0 0.0 2.3 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 RLN91314.1 - 0.0022 17.9 0.1 0.0046 16.9 0.1 1.6 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 RLN91314.1 - 0.043 12.9 0.0 0.19 10.8 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 RLN91314.1 - 0.18 11.7 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 RLN91315.1 - 3.1e-36 124.7 0.4 4.4e-36 124.2 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN91315.1 - 2.6e-24 86.1 0.4 3.2e-24 85.8 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN91315.1 - 0.00011 22.2 2.5 0.00025 21.0 1.6 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN91315.1 - 0.0044 16.5 0.1 0.0059 16.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 RLN91315.1 - 0.0067 15.6 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain VPS9 PF02204.18 RLN91318.1 - 9e-23 80.5 0.0 1.5e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Spectrin PF00435.21 RLN91318.1 - 0.62 10.6 3.8 0.24 11.9 0.3 2.1 2 0 0 2 2 2 0 Spectrin repeat adh_short PF00106.25 RLN91320.1 - 5.4e-60 202.2 10.0 1.2e-33 116.2 1.8 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN91320.1 - 4.4e-43 147.5 8.2 1.3e-21 77.2 1.3 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN91320.1 - 2.3e-06 27.7 2.1 0.0021 18.0 0.1 2.5 2 1 0 2 2 2 2 KR domain Epimerase PF01370.21 RLN91320.1 - 0.00018 21.1 0.6 0.00075 19.0 0.1 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 RLN91320.1 - 0.0057 16.6 0.1 0.0057 16.6 0.1 2.3 2 1 0 2 2 2 1 NAD(P)H-binding Pox_P4A PF03395.14 RLN91320.1 - 0.036 11.7 0.1 0.048 11.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus P4A protein NmrA PF05368.13 RLN91320.1 - 0.056 13.0 0.5 0.12 11.9 0.1 1.7 2 0 0 2 2 2 0 NmrA-like family NOP19 PF10863.8 RLN91320.1 - 0.082 12.7 0.0 0.64 9.8 0.0 2.0 2 0 0 2 2 2 0 Nucleolar protein 19 TPR_1 PF00515.28 RLN91322.1 - 1e-18 66.3 20.6 3.3e-06 26.7 0.1 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 RLN91322.1 - 1.1e-16 59.5 21.6 0.00049 20.0 0.1 8.5 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 RLN91322.1 - 3.2e-14 53.2 15.7 1.1e-06 29.1 0.7 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN91322.1 - 3.8e-12 45.4 14.2 0.025 14.8 0.2 8.3 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 RLN91322.1 - 8.3e-11 42.4 16.7 8.1e-06 26.4 0.2 6.6 4 2 3 7 7 7 4 Tetratricopeptide repeat Sel1 PF08238.12 RLN91322.1 - 1.3e-10 41.6 7.1 0.0086 16.7 0.0 5.6 6 0 0 6 6 5 3 Sel1 repeat TPR_11 PF13414.6 RLN91322.1 - 1.3e-10 40.8 0.8 1.1e-05 25.0 0.1 4.5 4 0 0 4 4 4 2 TPR repeat TPR_12 PF13424.6 RLN91322.1 - 1.9e-08 34.5 10.6 0.00013 22.2 0.3 6.7 5 1 0 6 6 6 2 Tetratricopeptide repeat zf-MYND PF01753.18 RLN91322.1 - 6.8e-08 32.5 11.0 6.8e-08 32.5 11.0 2.2 2 0 0 2 2 1 1 MYND finger TPR_14 PF13428.6 RLN91322.1 - 6.1e-07 29.7 28.0 0.26 12.2 0.1 8.9 7 3 2 9 9 7 3 Tetratricopeptide repeat HEPN_Swt1 PF18731.1 RLN91322.1 - 5.6e-05 23.5 1.6 7.7e-05 23.0 0.0 2.1 2 0 0 2 2 1 1 Swt1-like HEPN TPR_7 PF13176.6 RLN91322.1 - 0.0001 22.1 7.2 0.83 9.8 0.0 6.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN91322.1 - 0.00014 22.0 4.0 3.3 8.3 0.1 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN91322.1 - 0.00062 19.8 4.8 0.31 11.2 0.1 4.2 5 0 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 RLN91322.1 - 0.0012 19.0 5.3 1.2 9.4 0.6 4.7 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 RLN91322.1 - 0.0055 16.8 1.1 0.33 11.0 0.1 3.8 3 1 0 4 4 4 1 Domain of Unknown Function (DUF3856) Paf67 PF10255.9 RLN91322.1 - 0.016 14.3 0.3 0.049 12.6 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase I-associated factor PAF67 TPR_9 PF13371.6 RLN91322.1 - 0.025 14.7 4.5 0.19 11.9 0.1 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat MIT PF04212.18 RLN91322.1 - 0.1 12.6 7.7 0.24 11.5 0.1 3.3 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain zf-Di19 PF05605.12 RLN91322.1 - 1.6 9.1 5.1 4.5 7.6 5.1 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding RNA_pol_Rpc4 PF05132.14 RLN91322.1 - 3.2 8.1 9.6 47 4.4 0.1 3.5 3 0 0 3 3 3 0 RNA polymerase III RPC4 Ank_2 PF12796.7 RLN91323.1 - 1.8e-40 137.4 2.3 4.4e-07 30.4 0.2 7.5 2 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN91323.1 - 3.8e-37 126.2 15.9 1.5e-06 28.6 0.2 11.1 9 3 5 14 14 14 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN91323.1 - 3.7e-31 106.8 21.2 0.00026 21.2 0.2 13.4 4 2 8 13 13 13 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN91323.1 - 2.3e-25 85.9 8.4 0.47 11.2 0.1 15.1 13 2 2 15 15 15 4 Ankyrin repeat DUF5049 PF16468.5 RLN91323.1 - 3.8e-06 26.7 0.0 51 3.9 0.0 7.8 4 2 4 8 8 8 0 Domain of unknown function (DUF5049) Ank PF00023.30 RLN91323.1 - 0.00043 20.6 0.9 8.6 7.0 0.1 6.9 6 2 0 6 6 6 1 Ankyrin repeat DUF4411 PF14367.6 RLN91323.1 - 0.023 14.6 0.3 4.5 7.1 0.0 3.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4411) DUF3447 PF11929.8 RLN91323.1 - 0.064 13.2 0.0 4.5 7.3 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3447) Kelch_4 PF13418.6 RLN91325.1 - 4e-38 129.2 8.1 1.1e-09 38.2 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN91325.1 - 6.4e-32 109.0 0.0 4.4e-07 29.8 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RLN91325.1 - 1.8e-29 101.0 0.8 4.9e-05 23.5 0.0 6.1 5 1 1 6 6 6 5 Kelch motif Kelch_3 PF13415.6 RLN91325.1 - 1.1e-28 98.9 16.5 5.3e-07 29.8 0.0 7.7 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 RLN91325.1 - 3.8e-26 90.0 8.8 9.1e-09 35.0 0.2 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 RLN91325.1 - 1.4e-23 82.2 3.5 1.4e-08 34.2 0.2 6.6 6 0 0 6 6 6 5 Kelch motif Myb_DNA-binding PF00249.31 RLN91326.1 - 9.8e-40 134.5 9.2 3.8e-14 52.6 0.2 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN91326.1 - 8.2e-30 102.8 2.2 7.2e-13 48.6 0.0 3.6 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN91326.1 - 1.7e-05 24.6 0.5 0.00012 21.9 0.1 2.2 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 RLN91326.1 - 0.0054 16.7 0.0 0.47 10.5 0.0 2.8 1 1 2 3 3 3 1 SLIDE Nfu_N PF08712.11 RLN91327.1 - 5.5e-30 103.3 0.0 9.9e-30 102.4 0.0 1.4 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 RLN91327.1 - 6.1e-25 87.2 0.0 1e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain SMP_LBD PF17047.5 RLN91328.1 - 3.4e-05 23.4 0.0 5.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain PH PF00169.29 RLN91328.1 - 0.003 18.1 0.3 0.005 17.3 0.3 1.4 1 0 0 1 1 1 1 PH domain HOOK PF05622.12 RLN91329.1 - 1.6e-18 66.3 0.0 1.9e-18 66.0 0.0 1.0 1 0 0 1 1 1 1 HOOK protein Ank_2 PF12796.7 RLN91330.1 - 8.1e-135 439.7 19.1 2.7e-14 53.5 0.3 12.0 5 4 9 14 14 14 14 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN91330.1 - 6.2e-109 354.6 31.9 1.4e-11 44.4 0.7 13.9 8 4 8 16 16 16 14 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN91330.1 - 1.2e-102 335.1 29.5 4e-09 36.8 0.0 17.2 6 4 13 19 19 19 19 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN91330.1 - 1.4e-94 298.5 7.2 2.9e-06 27.2 0.0 21.4 22 0 0 22 22 22 15 Ankyrin repeat Ank PF00023.30 RLN91330.1 - 7.6e-92 298.1 14.9 1.1e-06 28.9 0.0 19.7 19 2 2 21 21 21 16 Ankyrin repeat Phage_T4_Ndd PF06591.11 RLN91330.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) AIM24 PF01987.17 RLN91331.1 - 9.6e-48 162.6 0.1 1.3e-47 162.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 WW PF00397.26 RLN91332.1 - 1.1e-09 38.2 6.8 0.00014 21.8 0.2 2.3 2 0 0 2 2 2 2 WW domain T3SSipB PF16535.5 RLN91332.1 - 0.075 13.5 0.3 0.13 12.8 0.3 1.4 1 1 0 1 1 1 0 Type III cell invasion protein SipB IQ PF00612.27 RLN91332.1 - 0.083 12.7 7.7 2.6 8.1 0.4 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF1180 PF06679.12 RLN91332.1 - 4.3 7.7 5.6 33 4.8 4.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) PDZ_6 PF17820.1 RLN91333.1 - 1e-16 60.5 2.3 0.082 12.8 0.1 6.5 6 0 0 6 6 6 5 PDZ domain PDZ PF00595.24 RLN91333.1 - 1.2e-12 47.9 2.3 0.00011 22.5 0.0 6.8 7 0 0 7 7 7 2 PDZ domain RTT107_BRCT_5 PF16770.5 RLN91333.1 - 9e-08 31.9 0.0 2.4e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 RLN91333.1 - 3.1e-06 27.5 0.0 1.5e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 RLN91333.1 - 9.2e-05 22.8 0.0 0.19 12.1 0.0 2.6 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 RLN91333.1 - 0.048 14.0 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain DDE_1 PF03184.19 RLN91335.1 - 0.004 16.8 0.0 0.0078 15.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN91335.1 - 0.0078 16.2 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 RLN91335.1 - 0.022 14.5 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease RTT107_BRCT_5 PF16770.5 RLN91337.1 - 1.9e-05 24.5 0.0 4.8e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 RLN91337.1 - 0.028 14.8 0.0 0.94 9.9 0.0 2.5 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain DUF4140 PF13600.6 RLN91337.1 - 0.084 13.3 0.8 0.31 11.5 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CAF20 PF17052.5 RLN91337.1 - 1.9 8.6 9.2 3.3 7.8 8.2 1.8 2 0 0 2 2 2 0 Cap associated factor SRP-alpha_N PF04086.13 RLN91337.1 - 4.7 7.0 13.7 7.8 6.3 13.7 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal START PF01852.19 RLN91338.1 - 0.013 14.9 0.1 0.02 14.3 0.1 1.3 1 0 0 1 1 1 0 START domain Pkinase_Tyr PF07714.17 RLN91339.1 - 2.1e-85 286.1 0.0 3.3e-42 144.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN91339.1 - 2e-84 283.1 0.0 1e-46 159.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Ank_4 PF13637.6 RLN91339.1 - 1.2e-22 79.9 0.4 1.7e-07 31.7 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN91339.1 - 1.9e-21 76.4 0.0 3.9e-11 43.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN91339.1 - 3.8e-19 68.5 4.3 1.5e-07 31.6 0.1 3.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) FYVE PF01363.21 RLN91339.1 - 1e-11 44.8 18.9 4.2e-11 42.8 18.9 1.9 1 1 0 1 1 1 1 FYVE zinc finger Ank_3 PF13606.6 RLN91339.1 - 6.3e-11 41.5 0.0 0.012 16.0 0.0 4.7 5 0 0 5 5 4 2 Ankyrin repeat Ank PF00023.30 RLN91339.1 - 7.5e-11 42.0 0.6 0.014 15.9 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Kdo PF06293.14 RLN91339.1 - 8.5e-05 22.0 0.1 0.38 10.1 0.1 2.7 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN91339.1 - 0.00042 20.3 0.1 1.2 9.0 0.0 2.8 2 0 0 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN91339.1 - 0.008 15.2 0.0 0.93 8.4 0.0 3.4 2 2 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 RLN91339.1 - 0.0094 14.8 0.0 0.26 10.0 0.0 2.5 2 0 0 2 2 2 1 Fungal protein kinase ABC1 PF03109.16 RLN91339.1 - 0.089 13.0 0.0 0.78 9.9 0.0 2.3 2 0 0 2 2 2 0 ABC1 family FYVE_2 PF02318.16 RLN91339.1 - 0.71 10.1 10.9 2.1 8.6 10.9 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger ABC_membrane PF00664.23 RLN91340.1 - 2.4e-53 181.6 37.3 7.3e-30 104.5 14.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN91340.1 - 1.7e-16 61.0 0.0 3.3e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN91340.1 - 1.5e-06 27.8 0.4 0.00059 19.3 0.4 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 RLN91340.1 - 0.00043 19.9 0.1 0.0008 19.0 0.1 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 RLN91340.1 - 0.0017 18.5 0.3 0.0041 17.2 0.3 1.6 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 RLN91340.1 - 0.0028 17.6 0.0 0.0058 16.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase KAP_NTPase PF07693.14 RLN91340.1 - 0.016 14.5 0.0 0.089 12.0 0.0 1.9 1 1 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.6 RLN91340.1 - 0.017 15.5 0.4 0.11 12.8 0.1 2.2 1 1 1 2 2 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 RLN91340.1 - 0.061 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.23 RLN91340.1 - 0.097 12.8 0.1 0.27 11.3 0.1 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 RLN91340.1 - 0.1 12.3 0.2 0.22 11.3 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN91340.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RLN91340.1 - 0.15 11.3 0.1 0.28 10.4 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 RLN91340.1 - 0.16 11.0 0.7 0.58 9.2 0.6 1.8 1 1 1 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 RLN91340.1 - 0.31 11.5 0.5 0.58 10.6 0.5 1.4 1 0 0 1 1 1 0 AAA domain Arm PF00514.23 RLN91341.1 - 3.8e-57 188.7 15.1 9.1e-08 31.9 0.0 9.7 9 1 1 10 10 10 9 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 RLN91341.1 - 1e-11 44.7 2.6 0.35 10.9 0.0 6.1 5 1 1 6 6 6 3 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 RLN91341.1 - 4.6e-11 42.9 24.5 6.2e-05 23.3 1.6 4.4 1 1 3 4 4 4 4 HEAT repeats HEAT PF02985.22 RLN91341.1 - 4.2e-10 39.0 7.3 1.3 9.4 0.0 8.3 9 0 0 9 9 8 3 HEAT repeat HEAT_EZ PF13513.6 RLN91341.1 - 7.4e-09 35.9 23.7 0.03 14.8 0.1 6.7 3 2 4 7 7 7 7 HEAT-like repeat Hydantoinase_B PF02538.14 RLN91341.1 - 4.3e-05 22.1 0.0 0.61 8.4 0.0 4.3 4 1 1 5 5 5 1 Hydantoinase B/oxoprolinase HEAT_PBS PF03130.16 RLN91341.1 - 0.0013 19.2 35.0 1.7 9.5 0.3 9.5 10 3 0 10 10 10 2 PBS lyase HEAT-like repeat DUF4800 PF16057.5 RLN91341.1 - 0.0017 17.7 0.0 0.3 10.3 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4800) Op_neuropeptide PF08035.11 RLN91341.1 - 0.0049 16.7 0.1 9.5 6.2 0.0 4.7 6 0 0 6 6 6 1 Opioids neuropeptide Phage_lysozyme2 PF18013.1 RLN91341.1 - 0.013 15.5 1.3 3.5 7.6 0.1 3.4 3 0 0 3 3 3 0 Phage tail lysozyme Arm_2 PF04826.13 RLN91341.1 - 0.036 13.5 0.0 26 4.1 0.0 3.6 1 1 2 4 4 4 0 Armadillo-like AA_kinase PF00696.28 RLN91342.1 - 1.4e-35 123.0 0.0 3.5e-35 121.7 0.0 1.7 1 1 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 RLN91342.1 - 0.18 11.6 0.1 1.3 8.9 0.1 2.3 2 0 0 2 2 2 0 ACT domain Sel1 PF08238.12 RLN91344.1 - 2e-42 142.7 29.4 2.5e-07 31.2 1.5 7.1 7 0 0 7 7 7 6 Sel1 repeat TPR_7 PF13176.6 RLN91344.1 - 0.2 11.8 9.9 2.7 8.2 0.3 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.32 RLN91345.1 - 3.8e-16 59.2 15.1 0.00019 22.2 0.5 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN91345.1 - 6.9e-06 26.3 0.0 0.24 11.7 0.0 2.8 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain AMPK1_CBM PF16561.5 RLN91345.1 - 0.25 11.6 2.6 0.26 11.6 0.2 2.2 3 0 0 3 3 3 0 Glycogen recognition site of AMP-activated protein kinase PX PF00787.24 RLN91346.1 - 2.1e-05 24.5 0.1 6.2e-05 22.9 0.1 1.7 1 1 0 1 1 1 1 PX domain Bclx_interact PF08945.10 RLN91347.1 - 1.7 8.5 6.2 9 6.2 1.8 2.6 2 0 0 2 2 2 0 Bcl-x interacting, BH3 domain Kazal_1 PF00050.21 RLN91348.1 - 2.5e-12 46.6 1.4 3.2e-12 46.2 1.4 1.2 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 RLN91348.1 - 6.8e-10 38.9 4.4 6.8e-10 38.9 4.4 1.4 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain DUF2799 PF10973.8 RLN91348.1 - 0.032 14.7 1.3 0.04 14.3 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2799) Kazal_2 PF07648.15 RLN91349.1 - 1.5e-14 53.8 20.6 2.4e-09 37.2 6.1 3.0 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Peptidase_S74 PF13884.6 RLN91349.1 - 9.8e-14 51.4 0.0 1.7e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Chaperone of endosialidase Kazal_1 PF00050.21 RLN91349.1 - 1.3e-11 44.3 15.7 1e-07 31.8 3.4 2.8 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain EGF_2 PF07974.13 RLN91349.1 - 5.3e-07 29.9 25.8 1.3e-06 28.6 6.8 3.0 2 0 0 2 2 2 2 EGF-like domain Bacillus_HBL PF05791.11 RLN91349.1 - 0.0054 16.6 0.0 0.0088 15.9 0.0 1.2 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) ADIP PF11559.8 RLN91349.1 - 0.029 14.5 0.4 0.047 13.8 0.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Sec2p PF06428.11 RLN91349.1 - 0.28 11.2 3.9 0.54 10.3 3.9 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p CENP-Q PF13094.6 RLN91349.1 - 0.39 10.9 5.9 0.74 10.0 5.9 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Sel1 PF08238.12 RLN91350.1 - 2e-39 133.1 25.7 8e-07 29.5 0.5 11.6 11 0 0 11 11 11 8 Sel1 repeat TPR_6 PF13174.6 RLN91350.1 - 0.045 14.4 10.3 23 5.9 0.7 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat HTH_Tnp_Tc5 PF03221.16 RLN91353.1 - 8.3e-06 25.7 0.0 1.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 RLN91353.1 - 0.034 13.9 0.0 0.099 12.4 0.0 1.7 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain HTH_32 PF13565.6 RLN91353.1 - 1 10.0 0.0 1 10.0 0.0 3.2 4 0 0 4 4 4 0 Homeodomain-like domain Hamartin PF04388.12 RLN91353.1 - 2.4 6.7 6.1 3.2 6.3 6.1 1.1 1 0 0 1 1 1 0 Hamartin protein HTH_Tnp_Tc5 PF03221.16 RLN91354.1 - 4.3e-10 39.5 0.1 2e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 RLN91354.1 - 1e-05 25.2 0.3 3.1e-05 23.6 0.1 1.9 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain HTH_32 PF13565.6 RLN91354.1 - 0.00018 22.1 0.1 0.00064 20.3 0.1 2.0 1 0 0 1 1 1 1 Homeodomain-like domain Adaptin_N PF01602.20 RLN91355.1 - 9.1e-93 311.6 9.6 2e-81 274.1 7.5 2.0 2 0 0 2 2 2 2 Adaptin N terminal region COP-gamma_platf PF08752.10 RLN91355.1 - 1.6e-41 142.0 0.1 4.3e-41 140.5 0.1 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 RLN91355.1 - 5.4e-25 87.8 0.0 3.7e-24 85.1 0.0 2.2 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 RLN91355.1 - 3.2e-14 53.1 6.9 9.1e-09 35.6 0.2 4.6 3 1 1 4 4 4 3 HEAT repeats Cnd1 PF12717.7 RLN91355.1 - 6.5e-12 45.8 9.9 0.00014 21.9 0.6 4.5 2 1 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RLN91355.1 - 0.015 15.5 10.9 25 5.5 0.2 5.9 6 0 0 6 6 6 0 HEAT repeat CmlA_N PF18456.1 RLN91355.1 - 0.018 14.4 0.2 0.032 13.5 0.2 1.3 1 0 0 1 1 1 0 Diiron non-heme beta-hydroxylase N-terminal domain Vac14_Fab1_bd PF12755.7 RLN91355.1 - 0.82 10.3 5.7 11 6.6 0.0 4.1 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.16 RLN91355.1 - 2.1 9.2 5.7 8 7.5 0.2 3.6 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Cupin_4 PF08007.12 RLN91356.1 - 1.9e-11 44.0 0.0 2.5e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein DNA_pol_phi PF04931.13 RLN91356.1 - 0.044 11.9 12.5 0.058 11.5 12.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 RLN91356.1 - 0.35 10.2 7.8 1.4 8.2 8.3 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 RLN91356.1 - 0.38 10.1 6.0 0.42 10.0 6.0 1.2 1 0 0 1 1 1 0 SDA1 Paf1 PF03985.13 RLN91356.1 - 0.72 8.8 3.2 1 8.3 3.2 1.2 1 0 0 1 1 1 0 Paf1 TFIIA PF03153.13 RLN91356.1 - 0.8 9.6 7.4 1 9.3 7.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 RLN91356.1 - 0.99 8.9 5.6 1.4 8.5 5.6 1.2 1 0 0 1 1 1 0 PPP4R2 Pox_Ag35 PF03286.14 RLN91356.1 - 1.1 9.0 4.0 1.7 8.4 4.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 RLN91356.1 - 1.5 7.0 8.5 1.7 6.7 8.5 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 RLN91356.1 - 2.4 8.0 6.3 1.9 8.3 4.6 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC45 PF02724.14 RLN91356.1 - 2.5 6.3 4.6 3.3 5.9 4.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Histone PF00125.24 RLN91357.1 - 2.8e-28 98.9 0.2 3e-28 98.8 0.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 RLN91357.1 - 0.00048 20.4 0.0 0.00054 20.3 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 RLN91357.1 - 0.0015 18.6 0.0 0.0017 18.5 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 RLN91357.1 - 0.015 15.4 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 RLN91357.1 - 0.043 14.1 0.0 0.049 13.9 0.0 1.1 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 RLN91358.1 - 2.4e-17 63.5 0.1 2.9e-17 63.3 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 RLN91358.1 - 0.00023 21.6 0.0 0.00041 20.8 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 RLN91358.1 - 0.0093 16.2 0.1 0.028 14.7 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 RLN91358.1 - 0.078 13.0 0.1 0.086 12.9 0.1 1.2 1 0 0 1 1 1 0 YscO-like protein PUB PF09409.10 RLN91360.1 - 1e-14 54.2 0.0 2.5e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 PUB domain DUF5572 PF17733.1 RLN91360.1 - 2.1e-12 46.7 0.6 1.2e-09 37.9 0.0 2.9 2 0 0 2 2 2 2 Family of unknown function (DUF5572) Kinesin_assoc PF16183.5 RLN91360.1 - 0.01 16.0 1.8 0.01 16.0 1.8 2.8 3 0 0 3 3 3 0 Kinesin-associated Tir_receptor_C PF07489.11 RLN91360.1 - 0.16 11.9 13.6 0.015 15.3 8.5 1.9 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus PEP-utilisers_N PF05524.13 RLN91360.1 - 0.38 10.9 4.6 10 6.3 0.1 2.9 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal CCDC-167 PF15188.6 RLN91360.1 - 0.67 10.3 5.6 2.8 8.3 0.1 2.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Bacillus_HBL PF05791.11 RLN91360.1 - 2.7 7.8 10.7 0.23 11.3 4.5 2.2 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Mx_ML PF17536.2 RLN91361.1 - 0.084 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Matrix and Matrix long proteins N-terminal MtN3_slv PF03083.16 RLN91362.1 - 3.9e-24 84.5 13.8 2e-14 53.4 6.3 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PIG-P PF08510.12 RLN91362.1 - 0.009 15.9 4.5 0.4 10.6 0.2 2.3 1 1 1 2 2 2 2 PIG-P MtN3_slv PF03083.16 RLN91363.1 - 4.3e-15 55.5 14.5 1.9e-14 53.5 6.4 2.4 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PAH PF02671.21 RLN91364.1 - 0.00091 19.3 0.2 0.002 18.2 0.2 1.5 1 0 0 1 1 1 1 Paired amphipathic helix repeat SUIM_assoc PF16619.5 RLN91364.1 - 2.1 8.5 15.4 0.078 13.1 1.0 3.7 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DLH PF01738.18 RLN91365.1 - 3.5e-21 75.8 0.3 6.6e-20 71.6 0.1 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family UPF0020 PF01170.18 RLN91365.1 - 4.5e-12 46.1 0.0 1e-10 41.6 0.1 2.8 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 RLN91365.1 - 0.0004 20.2 0.0 0.0033 17.1 0.0 2.1 2 0 0 2 2 2 1 DNA methylase MethyltransfD12 PF02086.15 RLN91365.1 - 0.11 12.2 0.0 0.82 9.3 0.0 2.2 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase Ion_trans PF00520.31 RLN91366.1 - 4.3e-06 26.1 15.0 4.3e-06 26.1 15.0 2.6 1 1 1 2 2 2 1 Ion transport protein ABC2_membrane PF01061.24 RLN91367.1 - 2.1e-33 115.5 24.5 2.1e-33 115.5 24.5 1.7 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN91367.1 - 1.5e-24 87.1 0.1 2.3e-24 86.4 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN91367.1 - 1.3e-06 28.5 0.0 0.033 14.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 RLN91367.1 - 0.0028 17.4 0.1 0.72 9.6 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 RLN91367.1 - 0.004 17.6 0.4 0.011 16.1 0.4 1.9 1 1 1 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 RLN91367.1 - 0.0049 16.3 0.0 3 7.2 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RLN91367.1 - 0.0072 16.1 0.1 0.02 14.7 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN91367.1 - 0.008 16.1 0.2 0.018 15.0 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 RLN91367.1 - 0.078 13.5 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 RLN91367.1 - 0.16 10.9 0.1 0.28 10.1 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC2_membrane_3 PF12698.7 RLN91367.1 - 0.17 11.0 24.5 0.3 10.2 24.5 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_25 PF13481.6 RLN91367.1 - 0.21 11.2 0.2 0.51 9.9 0.1 1.6 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.23 RLN91368.1 - 9.5e-101 337.0 22.0 2.8e-52 178.1 1.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN91368.1 - 1.1e-34 119.9 0.0 2.3e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN91368.1 - 3.9e-07 29.7 0.0 0.00016 21.2 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RLN91368.1 - 0.00072 19.2 0.1 0.002 17.8 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 RLN91368.1 - 0.0012 18.1 0.0 0.0025 17.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 RLN91368.1 - 0.0038 17.6 0.0 0.01 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 RLN91368.1 - 0.0094 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 RLN91368.1 - 0.017 14.9 0.1 0.16 11.7 0.0 2.1 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 RLN91368.1 - 0.021 15.1 0.0 0.12 12.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RLN91368.1 - 0.022 14.6 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 RLN91368.1 - 0.057 13.8 0.1 0.52 10.7 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 RLN91368.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_7 PF12775.7 RLN91368.1 - 0.15 11.6 0.0 0.38 10.2 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region SRP54_N PF02881.19 RLN91370.1 - 0.013 15.7 0.0 0.026 14.7 0.0 1.6 1 1 1 2 2 2 0 SRP54-type protein, helical bundle domain ER_lumen_recept PF00810.18 RLN91371.1 - 5.4e-19 69.5 5.5 8.7e-19 68.8 5.5 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor Ank_2 PF12796.7 RLN91372.1 - 5.3e-22 78.2 0.6 1.3e-11 44.9 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN91372.1 - 3.2e-20 71.9 4.8 1.6e-07 31.4 0.4 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN91372.1 - 2.6e-19 69.3 0.2 1.4e-07 31.9 0.1 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN91372.1 - 8.9e-19 67.0 5.2 3.3e-06 27.3 0.1 5.3 5 0 0 5 5 5 4 Ankyrin repeat FYVE PF01363.21 RLN91372.1 - 8.6e-15 54.6 11.8 1.6e-14 53.7 11.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger Ank_3 PF13606.6 RLN91372.1 - 1.8e-14 52.4 0.9 0.016 15.7 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat FYVE_2 PF02318.16 RLN91372.1 - 0.0031 17.7 7.5 0.0031 17.7 7.5 1.6 2 0 0 2 2 2 1 FYVE-type zinc finger NT-C2 PF10358.9 RLN91373.1 - 0.083 12.6 0.0 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins HPS3_N PF14761.6 RLN91374.1 - 3.4e-10 39.8 0.2 1.2e-08 34.8 0.1 3.0 2 1 0 2 2 2 1 Hermansky-Pudlak syndrome 3 HPS3_Mid PF14762.6 RLN91374.1 - 0.0046 15.8 0.1 0.075 11.8 0.0 2.3 2 0 0 2 2 2 1 Hermansky-Pudlak syndrome 3, middle region DUF2039 PF10217.9 RLN91376.1 - 1.2e-16 60.8 3.0 1.7e-16 60.3 3.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) 2-Hacid_dh_C PF02826.19 RLN91378.1 - 2.3e-57 193.2 0.0 3.8e-57 192.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 RLN91378.1 - 4.9e-30 103.9 0.0 5.6e-30 103.7 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 RLN91378.1 - 1.7e-06 28.3 0.1 5.7e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 RLN91378.1 - 0.0027 17.8 0.5 0.0059 16.7 0.1 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 RLN91378.1 - 0.0075 16.2 0.3 0.023 14.6 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 RLN91378.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 RLN91378.1 - 0.054 12.8 0.1 2.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DNA_pol_A_exo1 PF01612.20 RLN91378.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 3'-5' exonuclease 2-Hacid_dh_C PF02826.19 RLN91379.1 - 6.1e-57 191.9 0.0 1.1e-56 191.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 RLN91379.1 - 1.5e-29 102.4 0.1 1.8e-29 102.1 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 RLN91379.1 - 1.4e-06 28.6 0.1 1.2e-05 25.6 0.0 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 RLN91379.1 - 1.2e-05 25.4 0.1 2.5e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 RLN91379.1 - 9.6e-05 22.0 0.0 0.00021 20.9 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 RLN91379.1 - 0.0078 16.1 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_N PF05222.15 RLN91379.1 - 0.026 14.8 0.0 0.74 10.1 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, N-terminal domain F420_oxidored PF03807.17 RLN91379.1 - 0.028 15.0 0.4 0.7 10.5 0.1 2.7 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent CoA_binding_2 PF13380.6 RLN91379.1 - 0.042 14.3 0.1 0.14 12.7 0.0 1.9 1 1 0 1 1 1 0 CoA binding domain Putative_PNPOx PF01243.20 RLN91379.1 - 0.043 14.0 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase NMT1 PF09084.11 RLN91379.1 - 0.11 12.4 0.0 14 5.5 0.0 2.5 2 1 0 2 2 2 0 NMT1/THI5 like NAD_binding_7 PF13241.6 RLN91379.1 - 0.14 12.6 0.1 1.7 9.1 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 RLN91379.1 - 0.16 11.2 0.6 1.1 8.5 0.6 2.2 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 RLN91379.1 - 0.28 11.3 4.7 4.1 7.5 0.1 2.9 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Pkinase_Tyr PF07714.17 RLN91380.1 - 5.3e-39 134.0 0.0 7.9e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN91380.1 - 4.2e-27 95.2 0.0 7.5e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ABC_membrane PF00664.23 RLN91381.1 - 1.3e-49 169.4 29.9 7.2e-27 94.7 6.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN91381.1 - 2.9e-46 157.4 0.0 4.9e-25 88.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN91381.1 - 6e-09 35.6 3.6 0.00062 19.3 0.2 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RLN91381.1 - 5.4e-06 26.9 0.7 0.0088 16.4 0.0 2.9 2 2 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 RLN91381.1 - 4.1e-05 23.5 0.0 0.28 11.1 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 RLN91381.1 - 0.00019 21.7 1.4 0.042 14.1 0.0 3.2 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 RLN91381.1 - 0.00033 20.7 0.0 0.044 13.9 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 RLN91381.1 - 0.00043 20.1 0.6 3.6 7.3 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_23 PF13476.6 RLN91381.1 - 0.00078 20.0 0.4 1.3 9.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 RLN91381.1 - 0.0013 19.2 1.2 0.041 14.3 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 RLN91381.1 - 0.0025 18.2 0.0 0.7 10.3 0.0 3.1 3 0 0 3 3 3 1 RNA helicase AAA_21 PF13304.6 RLN91381.1 - 0.0042 17.0 0.1 5.9 6.6 0.1 3.8 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 RLN91381.1 - 0.012 15.2 0.2 0.55 9.8 0.0 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.25 RLN91381.1 - 0.013 15.2 0.0 3.1 7.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 RLN91381.1 - 0.015 15.8 0.0 6.4 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 RLN91381.1 - 0.024 14.4 0.3 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 RLN91381.1 - 0.034 13.9 0.3 6.3 6.6 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 RLN91381.1 - 0.05 13.5 0.1 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 RLN91381.1 - 0.056 13.0 0.1 5.3 6.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 RLN91381.1 - 0.1 12.6 1.0 2.6 8.1 0.0 2.7 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 RLN91381.1 - 0.13 11.5 0.3 3.3 7.0 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.6 RLN91381.1 - 0.37 11.1 1.4 2.5 8.4 0.2 2.9 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit DEAD PF00270.29 RLN91381.1 - 0.57 9.9 1.7 8.3 6.1 1.8 2.6 2 1 0 2 2 2 0 DEAD/DEAH box helicase MFS_1 PF07690.16 RLN91383.1 - 1.3e-44 152.6 46.1 9.5e-34 116.9 30.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN91383.1 - 1e-29 103.7 19.4 3.7e-28 98.6 19.4 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 RLN91383.1 - 0.0019 17.5 4.4 0.0019 17.5 4.4 2.4 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF543 PF04418.12 RLN91383.1 - 1.2 9.2 3.7 1.8 8.6 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF543) OrfB_Zn_ribbon PF07282.11 RLN91384.1 - 0.11 12.4 1.4 0.52 10.3 1.4 2.2 1 1 0 1 1 1 0 Putative transposase DNA-binding domain YabA PF06156.13 RLN91385.1 - 0.0024 18.4 1.4 0.0035 17.9 1.4 1.3 1 0 0 1 1 1 1 Initiation control protein YabA TSC22 PF01166.18 RLN91385.1 - 0.0041 17.4 2.9 0.0082 16.4 2.9 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF3450 PF11932.8 RLN91385.1 - 0.0082 15.5 2.5 0.0093 15.3 2.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Phlebovirus_NSM PF07246.11 RLN91385.1 - 0.0095 15.3 1.1 0.011 15.1 1.1 1.1 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M bZIP_2 PF07716.15 RLN91385.1 - 0.019 15.1 4.1 0.019 15.1 4.1 2.2 2 0 0 2 2 2 0 Basic region leucine zipper DUF3523 PF12037.8 RLN91385.1 - 0.021 14.2 7.0 0.027 13.9 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) M PF02370.16 RLN91385.1 - 0.066 13.8 3.1 0.066 13.8 3.1 2.3 2 0 0 2 2 2 0 M protein repeat DivIC PF04977.15 RLN91385.1 - 0.13 12.0 8.9 6.1 6.7 8.9 2.2 1 1 0 1 1 1 0 Septum formation initiator Ax_dynein_light PF10211.9 RLN91385.1 - 0.14 12.1 4.8 0.2 11.6 4.8 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain Atg14 PF10186.9 RLN91385.1 - 0.2 10.7 3.1 0.23 10.5 3.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 RLN91385.1 - 0.43 11.1 8.4 0.73 10.3 8.4 1.4 1 0 0 1 1 1 0 Cell division protein ZapB DUF3043 PF11241.8 RLN91385.1 - 1.6 8.8 6.4 2.3 8.2 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) PKcGMP_CC PF16808.5 RLN91385.1 - 2.3 8.1 6.6 0.22 11.4 1.9 1.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PRO8NT PF08082.11 RLN91386.1 - 3.2e-05 23.9 2.0 4.2e-05 23.5 0.5 1.8 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain VirC2 PF07181.11 RLN91386.1 - 0.085 12.3 0.0 0.1 12.1 0.0 1.0 1 0 0 1 1 1 0 VirC2 protein Thioredoxin PF00085.20 RLN91387.1 - 7.3e-66 218.6 0.0 8.8e-32 109.2 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 RLN91387.1 - 1.6e-19 70.4 0.0 1.3e-08 34.6 0.0 2.1 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family ERp29 PF07749.12 RLN91387.1 - 2.8e-19 69.8 0.7 6.9e-19 68.6 0.7 1.7 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 RLN91387.1 - 1.3e-15 57.7 0.4 4.7e-07 30.2 0.0 3.1 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 RLN91387.1 - 2.8e-09 37.0 0.0 0.0015 18.7 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 RLN91387.1 - 1.3e-07 31.6 0.3 0.006 16.5 0.0 2.7 2 1 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 RLN91387.1 - 1.6e-07 31.5 0.2 0.0075 16.6 0.0 3.7 2 2 2 4 4 4 2 Thioredoxin-like TraF PF13728.6 RLN91387.1 - 1.5e-05 25.0 0.0 0.066 13.0 0.0 2.4 2 0 0 2 2 2 2 F plasmid transfer operon protein Redoxin PF08534.10 RLN91387.1 - 0.00016 21.4 0.3 0.31 10.7 0.1 2.3 2 0 0 2 2 2 2 Redoxin HyaE PF07449.11 RLN91387.1 - 0.00027 20.9 0.0 0.58 10.1 0.0 2.5 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 RLN91387.1 - 0.0018 18.3 0.0 2.7 8.1 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_9 PF14595.6 RLN91387.1 - 0.019 14.7 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin Pkinase_Tyr PF07714.17 RLN91388.1 - 2.9e-49 167.7 0.0 4.8e-49 167.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN91388.1 - 5.6e-46 157.0 0.0 9.8e-46 156.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Elicitin PF00964.17 RLN91389.1 - 7.3e-77 253.6 25.8 2.2e-21 75.8 1.9 4.4 4 0 0 4 4 4 4 Elicitin Defensin_5 PF18251.1 RLN91389.1 - 0.062 13.4 4.2 37 4.5 0.1 4.0 3 0 0 3 3 3 0 Fungal defensin Copsin Dynamin_N PF00350.23 RLN91390.1 - 0.039 14.0 1.5 0.068 13.2 1.5 1.4 1 0 0 1 1 1 0 Dynamin family Elicitin PF00964.17 RLN91391.1 - 1.9e-21 76.0 1.7 1.9e-21 76.0 1.7 2.2 2 0 0 2 2 2 1 Elicitin Herpes_pp85 PF04637.12 RLN91391.1 - 0.6 8.5 7.7 0.91 7.9 7.7 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF4179 PF13786.6 RLN91391.1 - 0.9 10.1 4.8 3.4 8.2 4.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) PP_M1 PF03012.14 RLN91391.1 - 1.9 8.0 4.4 2.6 7.5 4.4 1.1 1 0 0 1 1 1 0 Phosphoprotein Elicitin PF00964.17 RLN91392.1 - 5.5e-21 74.5 1.6 5.5e-21 74.5 1.6 1.9 2 0 0 2 2 2 1 Elicitin Elicitin PF00964.17 RLN91394.1 - 5e-40 135.5 10.5 6.1e-20 71.1 3.0 2.4 2 0 0 2 2 2 2 Elicitin POTRA_2 PF08479.11 RLN91394.1 - 0.011 15.5 0.0 3.9 7.4 0.0 2.3 2 0 0 2 2 2 0 POTRA domain, ShlB-type Flavi_DEAD PF07652.14 RLN91394.1 - 0.04 13.9 0.2 7.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Flavivirus DEAD domain LRR_9 PF14580.6 RLN91395.1 - 0.041 13.4 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat WD40 PF00400.32 RLN91396.1 - 6.5e-11 42.6 0.0 0.088 13.7 0.0 5.9 6 1 0 6 6 6 2 WD domain, G-beta repeat PCP_red PF08369.10 RLN91396.1 - 1.1e-05 25.5 3.9 2.1e-05 24.6 3.9 1.5 1 0 0 1 1 1 1 Proto-chlorophyllide reductase 57 kD subunit Acyl-CoA_dh_2 PF08028.11 RLN91396.1 - 2.5 8.4 5.9 0.93 9.8 2.5 2.0 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain F-actin_cap_A PF01267.17 RLN91397.1 - 1e-59 202.2 0.0 8.8e-58 195.8 0.0 2.7 1 1 0 1 1 1 1 F-actin capping protein alpha subunit Ras PF00071.22 RLN91398.1 - 5.1e-10 39.2 0.0 1.4e-05 24.8 0.0 2.5 2 1 0 2 2 2 2 Ras family Roc PF08477.13 RLN91398.1 - 1.4e-09 38.2 0.1 3.6e-08 33.7 0.1 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN91398.1 - 3.6e-06 26.5 0.0 0.012 15.0 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RLN91398.1 - 3.8e-05 23.7 0.0 7.5e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RLN91398.1 - 0.00011 22.7 0.0 0.00016 22.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.20 RLN91398.1 - 0.0028 16.9 0.0 1.1 8.3 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit NACHT PF05729.12 RLN91398.1 - 0.0031 17.5 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 RLN91398.1 - 0.0034 17.6 0.0 0.0041 17.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 RLN91398.1 - 0.0039 17.1 0.1 0.0062 16.4 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 RLN91398.1 - 0.0046 17.5 0.0 0.0081 16.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 RLN91398.1 - 0.0048 16.6 0.0 0.0097 15.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN91398.1 - 0.0065 16.7 0.0 0.015 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 RLN91398.1 - 0.0068 16.0 0.1 0.03 13.9 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.18 RLN91398.1 - 0.0092 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Septin MCM PF00493.23 RLN91398.1 - 0.015 14.4 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_23 PF13476.6 RLN91398.1 - 0.022 15.2 0.0 0.035 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 RLN91398.1 - 0.024 14.4 0.0 0.058 13.1 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 RLN91398.1 - 0.034 13.9 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RLN91398.1 - 0.058 13.9 0.1 0.091 13.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 RLN91398.1 - 0.066 13.0 0.0 0.099 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SRPRB PF09439.10 RLN91398.1 - 0.068 12.6 0.1 1.2 8.5 0.1 2.1 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 RLN91398.1 - 0.08 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 RLN91398.1 - 0.082 12.5 0.0 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PLAC9 PF15205.6 RLN91398.1 - 0.089 13.2 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Placenta-specific protein 9 AAA PF00004.29 RLN91398.1 - 0.097 13.1 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3987 PF13148.6 RLN91398.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) TsaE PF02367.17 RLN91398.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 RLN91398.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 RLN91398.1 - 0.17 12.3 0.0 0.27 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 RLN91398.1 - 0.21 11.3 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DAP3 PF10236.9 RLN91398.1 - 0.21 10.7 0.0 0.31 10.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 E1-E2_ATPase PF00122.20 RLN91403.1 - 9.3e-27 93.7 0.1 2.7e-26 92.2 0.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 RLN91403.1 - 1.7e-09 38.3 0.3 0.00023 21.5 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 RLN91403.1 - 5.7e-07 29.7 0.3 1.8e-06 28.1 0.3 1.9 1 0 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.26 RLN91403.1 - 0.0035 17.0 0.0 0.0079 15.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 RLN91403.1 - 0.021 14.9 0.0 0.059 13.4 0.0 1.8 1 0 0 1 1 1 0 Cation transport ATPase (P-type) ANAPC5 PF12862.7 RLN91404.1 - 2.7e-24 85.1 0.0 1.6e-23 82.6 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 ANAPC3 PF12895.7 RLN91404.1 - 3.7e-05 23.9 3.8 0.0028 17.8 0.1 3.4 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 RLN91404.1 - 0.02 15.4 5.5 4.6 7.8 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Ferritin PF00210.24 RLN91404.1 - 0.049 13.6 0.0 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 Ferritin-like domain Methyltransf_16 PF10294.9 RLN91404.1 - 0.065 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase HemY_N PF07219.13 RLN91404.1 - 0.13 12.4 5.8 8.7 6.6 0.4 3.7 3 1 0 3 3 3 0 HemY protein N-terminus TPR_14 PF13428.6 RLN91404.1 - 0.21 12.5 5.5 10 7.2 0.1 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN91404.1 - 0.44 10.8 5.0 41 4.6 0.0 5.0 5 1 1 6 6 6 0 Tetratricopeptide repeat Mannosyl_trans3 PF11051.8 RLN91405.1 - 4.6e-30 104.9 0.0 9e-19 67.9 0.0 2.2 2 0 0 2 2 2 2 Mannosyltransferase putative SMG1 PF15785.5 RLN91406.1 - 3.1e-19 68.8 1.1 1.7e-14 53.2 0.1 2.7 3 0 0 3 3 3 2 Serine/threonine-protein kinase smg-1 FAT PF02259.23 RLN91406.1 - 0.00063 19.1 0.1 0.003 16.8 0.1 2.0 1 1 0 1 1 1 1 FAT domain La PF05383.17 RLN91409.1 - 8e-14 51.4 0.0 1.5e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 RLN91409.1 - 0.00017 21.3 0.0 0.0027 17.5 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.23 RLN91410.1 - 1.2e-11 44.3 6.6 2.4e-11 43.3 6.6 1.6 1 0 0 1 1 1 1 G-patch domain OCRE PF17780.1 RLN91410.1 - 1.2e-07 31.6 9.9 2.3e-07 30.7 9.9 1.4 1 0 0 1 1 1 1 OCRE domain G-patch_2 PF12656.7 RLN91410.1 - 0.00037 20.5 3.8 0.00037 20.5 3.8 2.3 2 0 0 2 2 2 1 G-patch domain NEMP PF10225.9 RLN91410.1 - 0.27 10.9 0.3 0.47 10.1 0.3 1.3 1 0 0 1 1 1 0 NEMP family zf-met PF12874.7 RLN91411.1 - 3.9e-05 23.9 0.4 3.9e-05 23.9 0.4 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RLN91411.1 - 6.1e-05 23.2 0.2 6.1e-05 23.2 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding SNRNP27 PF08648.12 RLN91411.1 - 0.0051 16.9 1.4 0.0051 16.9 1.4 2.3 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins Spc29 PF17082.5 RLN91411.1 - 0.0069 16.3 1.0 0.0091 15.9 0.4 1.7 1 1 0 1 1 1 1 Spindle Pole Component 29 HycI PF01750.18 RLN91411.1 - 0.011 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase maturation protease GET2 PF08690.10 RLN91411.1 - 0.17 11.5 2.4 0.27 10.9 2.4 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Macoilin PF09726.9 RLN91411.1 - 1.1 7.8 10.3 0.055 12.0 5.1 1.4 2 0 0 2 2 2 0 Macoilin family Peptidase_S49_N PF08496.10 RLN91411.1 - 4.8 7.2 10.5 5.7 7.0 5.9 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal zf-U1 PF06220.12 RLN91411.1 - 5.9 6.7 7.1 0.54 10.1 0.5 2.2 2 0 0 2 2 2 0 U1 zinc finger Vfa1 PF08432.10 RLN91411.1 - 9.8 6.5 16.1 0.41 11.0 9.0 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 AhpC-TSA PF00578.21 RLN91412.1 - 4e-28 97.8 0.0 2.2e-24 85.7 0.0 2.2 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin PF00085.20 RLN91412.1 - 2.6e-19 69.1 0.0 4.2e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin 1-cysPrx_C PF10417.9 RLN91412.1 - 6.4e-14 51.5 0.0 1.6e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 RLN91412.1 - 1.3e-11 44.4 0.0 2.7e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 Redoxin Thioredoxin_2 PF13098.6 RLN91412.1 - 4.1e-05 24.0 0.1 0.00029 21.2 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 RLN91412.1 - 0.0003 20.6 0.0 0.00057 19.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 RLN91412.1 - 0.015 15.6 0.0 0.21 11.9 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin-like Pkinase PF00069.25 RLN91413.1 - 6.5e-49 166.7 0.0 3.2e-46 157.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN91413.1 - 2.6e-15 56.4 0.0 1e-13 51.2 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN91413.1 - 0.012 15.0 0.0 0.93 8.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 RLN91413.1 - 0.054 12.8 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RLN91413.1 - 0.067 12.8 0.1 0.23 11.0 0.1 1.8 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kinesin PF00225.23 RLN91414.1 - 1.4e-106 356.2 0.1 1.2e-105 353.2 0.1 2.1 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN91414.1 - 5.4e-25 88.1 0.0 1.1e-24 87.0 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Thioredoxin_8 PF13905.6 RLN91415.1 - 3.1e-23 81.9 0.0 4.1e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 RLN91415.1 - 1.3e-08 34.8 0.0 1.8e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 RLN91415.1 - 1.1e-07 31.8 0.0 3.5e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_9 PF14595.6 RLN91415.1 - 4.3e-06 26.5 0.0 0.00015 21.5 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin Redoxin PF08534.10 RLN91415.1 - 0.00016 21.4 0.0 0.0002 21.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 RLN91415.1 - 0.0062 17.0 0.0 0.012 16.1 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain STAS_2 PF13466.6 RLN91415.1 - 0.0082 16.5 0.7 0.074 13.4 0.1 2.5 3 1 0 3 3 3 1 STAS domain Thioredoxin_7 PF13899.6 RLN91415.1 - 0.019 15.1 0.0 0.072 13.3 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like SCO1-SenC PF02630.14 RLN91415.1 - 0.036 14.0 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 SCO1/SenC Thioredoxin_8 PF13905.6 RLN91416.1 - 1.1e-23 83.3 0.0 1.5e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 RLN91416.1 - 2.8e-09 37.0 0.0 3.5e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 RLN91416.1 - 6.8e-06 26.0 0.0 9.7e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Redoxin PF08534.10 RLN91416.1 - 0.00023 20.9 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 RLN91416.1 - 0.00024 20.9 0.0 0.0014 18.4 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 RLN91416.1 - 0.0061 17.0 0.0 0.0098 16.3 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 RLN91416.1 - 0.01 16.0 0.0 0.04 14.1 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like DUF953 PF06110.11 RLN91416.1 - 0.08 12.6 0.0 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) EF-hand_6 PF13405.6 RLN91417.1 - 0.00012 21.7 0.4 0.00041 20.1 0.2 1.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 RLN91417.1 - 0.00025 20.3 0.1 0.00054 19.3 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 RLN91417.1 - 0.00044 20.7 0.1 0.00086 19.7 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN91417.1 - 0.011 15.2 0.3 0.019 14.4 0.3 1.4 1 0 0 1 1 1 0 EF hand DDE_Tnp_IS66 PF03050.14 RLN91418.1 - 0.088 12.3 0.3 0.14 11.6 0.3 1.2 1 0 0 1 1 1 0 Transposase IS66 family NDUF_B12 PF08122.12 RLN91419.1 - 0.0019 18.2 0.1 0.0044 17.0 0.1 1.6 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family FYVE PF01363.21 RLN91420.1 - 6.1e-14 51.9 9.8 1.1e-13 51.0 9.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger Ank_5 PF13857.6 RLN91420.1 - 6.4e-05 23.2 0.3 0.0022 18.3 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) DUF5564 PF17719.1 RLN91420.1 - 0.0026 17.9 0.0 0.0095 16.1 0.0 2.0 1 0 0 1 1 1 1 Family of unknown function (DUF5564) Ank_4 PF13637.6 RLN91420.1 - 0.0068 17.0 0.3 0.016 15.8 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DEAD PF00270.29 RLN91422.1 - 1.2e-43 148.9 0.3 1.7e-43 148.4 0.3 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN91422.1 - 1.8e-29 102.3 1.3 5.4e-28 97.6 0.4 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN91422.1 - 6e-05 23.1 0.0 9.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 RLN91422.1 - 0.00083 18.6 0.1 0.0013 18.0 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 RLN91422.1 - 0.013 14.9 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.6 RLN91422.1 - 0.023 14.4 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Aldo_ket_red PF00248.21 RLN91424.1 - 4.3e-70 236.2 0.0 4.8e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 RLN91425.1 - 7.1e-16 58.3 0.0 7.6e-16 58.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EF-hand_7 PF13499.6 RLN91426.1 - 0.00027 21.3 0.0 0.00073 19.9 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN91426.1 - 0.02 14.8 0.2 0.18 11.8 0.2 2.3 2 0 0 2 2 2 0 EF-hand domain Cytomega_UL20A PF05984.12 RLN91426.1 - 0.073 13.4 0.3 0.25 11.7 0.3 1.9 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein EF-hand_1 PF00036.32 RLN91426.1 - 0.27 10.9 0.9 1.7 8.4 0.5 2.3 2 0 0 2 2 2 0 EF hand DUF4539 PF15072.6 RLN91427.1 - 2.3e-18 66.0 0.0 4.2e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) NuA4 PF09340.10 RLN91427.1 - 0.00018 21.3 0.0 0.0007 19.4 0.0 2.1 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Acyltransferase PF01553.21 RLN91428.1 - 1e-05 25.1 0.0 0.0016 18.0 0.0 2.4 1 1 1 2 2 2 2 Acyltransferase Arm PF00514.23 RLN91429.1 - 4.4e-42 140.9 10.5 1.1e-06 28.5 0.0 9.6 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN91429.1 - 1.2e-06 28.9 23.1 0.0027 18.1 0.7 4.7 1 1 4 5 5 5 3 HEAT repeats HEAT_EZ PF13513.6 RLN91429.1 - 1.9e-06 28.3 21.3 0.00014 22.2 0.3 7.1 6 3 2 8 8 8 2 HEAT-like repeat HEAT_PBS PF03130.16 RLN91429.1 - 8.3e-06 26.0 29.8 2.7 8.9 0.3 9.3 10 2 0 10 10 10 3 PBS lyase HEAT-like repeat HEAT PF02985.22 RLN91429.1 - 0.00062 19.8 7.6 1.3e+02 3.3 0.0 7.8 8 0 0 8 8 8 0 HEAT repeat UNC45-central PF11701.8 RLN91429.1 - 0.012 15.6 0.2 1.2 9.0 0.3 2.8 2 1 1 3 3 3 0 Myosin-binding striated muscle assembly central Hydantoinase_B PF02538.14 RLN91429.1 - 0.035 12.5 0.0 8.3 4.7 0.0 3.8 2 1 2 4 4 4 0 Hydantoinase B/oxoprolinase Pico_P2B PF01552.17 RLN91429.1 - 0.18 12.0 0.1 27 5.0 0.0 3.2 2 1 0 3 3 3 0 Picornavirus 2B protein Pribosyltran_N PF13793.6 RLN91430.1 - 3e-43 146.5 0.1 4.8e-42 142.6 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 RLN91430.1 - 6.6e-20 71.9 0.0 2.1e-19 70.3 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 RLN91430.1 - 1.4e-06 28.0 0.1 1.2e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain HSP90 PF00183.18 RLN91431.1 - 1.1e-92 311.6 6.6 7.8e-86 289.0 2.5 3.1 1 1 2 3 3 3 3 Hsp90 protein HATPase_c_3 PF13589.6 RLN91431.1 - 1e-09 38.3 0.1 2.2e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 RLN91431.1 - 9.8e-07 29.3 0.3 2.8e-06 27.8 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TB2_DP1_HVA22 PF03134.19 RLN91432.1 - 5.7e-29 99.9 4.4 7.9e-29 99.4 3.5 1.7 2 0 0 2 2 2 1 TB2/DP1, HVA22 family PerC PF06069.11 RLN91432.1 - 0.078 13.2 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 PerC transcriptional activator FAD-oxidase_C PF02913.19 RLN91433.1 - 8.6e-57 192.6 0.1 1.2e-56 192.1 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 RLN91433.1 - 8.8e-34 116.2 1.3 1.1e-29 102.9 0.3 2.5 2 0 0 2 2 2 2 FAD binding domain DnaJ PF00226.31 RLN91434.1 - 7.2e-13 48.5 0.2 7.2e-13 48.5 0.2 3.5 3 1 0 3 3 3 1 DnaJ domain Peptidase_U57 PF05582.12 RLN91434.1 - 0.44 9.8 10.0 13 4.9 8.5 2.3 2 0 0 2 2 2 0 YabG peptidase U57 FUSC PF04632.12 RLN91434.1 - 4.8 5.6 7.1 8.6 4.8 7.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ank_5 PF13857.6 RLN91435.1 - 8.3e-36 121.6 29.6 0.00023 21.4 0.1 14.9 4 2 12 16 16 16 11 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN91435.1 - 3.4e-35 120.5 11.4 1.9e-08 34.8 0.4 6.5 2 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN91435.1 - 1.6e-30 105.1 18.8 8.3e-06 26.3 0.1 10.8 5 4 6 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN91435.1 - 2.5e-21 73.5 13.1 3.2 8.6 0.0 14.6 12 2 4 16 16 16 4 Ankyrin repeat DUF5049 PF16468.5 RLN91435.1 - 9.2e-05 22.3 0.1 30 4.6 0.0 6.2 6 2 2 8 8 8 1 Domain of unknown function (DUF5049) Ank PF00023.30 RLN91435.1 - 0.0017 18.7 2.9 52 4.5 0.0 7.8 7 3 0 7 7 7 0 Ankyrin repeat ATG2_CAD PF13329.6 RLN91436.1 - 1.2e-07 31.6 0.0 8e-07 28.9 0.0 2.2 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif Arm PF00514.23 RLN91437.1 - 5.8e-06 26.2 0.0 0.025 14.6 0.0 3.2 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 RLN91437.1 - 0.022 14.8 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 RLN91437.1 - 0.31 11.8 1.9 7.9 7.5 0.2 2.5 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat DUF3460 PF11943.8 RLN91438.1 - 3.5 8.0 4.8 1.1 9.6 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3460) SlyX PF04102.12 RLN91439.1 - 0.0053 17.3 0.0 4.3 8.0 0.0 2.7 2 1 1 3 3 3 2 SlyX HrpB7 PF09486.10 RLN91439.1 - 0.023 15.1 4.9 2.1 8.7 0.1 2.9 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) DUF1664 PF07889.12 RLN91439.1 - 0.027 14.5 0.2 3.2 7.8 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF3552 PF12072.8 RLN91439.1 - 0.029 13.8 0.0 7.2 6.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF5446 PF17522.2 RLN91439.1 - 0.048 13.8 0.0 3.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5446) Ank_4 PF13637.6 RLN91440.1 - 7.3e-24 83.8 21.8 1.7e-07 31.6 0.1 10.3 8 3 3 11 11 11 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN91440.1 - 2.4e-21 76.1 6.0 1.1e-07 32.3 0.2 6.4 3 2 1 7 7 7 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN91440.1 - 3e-14 52.9 18.1 0.0077 16.5 0.1 10.7 7 2 4 12 12 12 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN91440.1 - 6.8e-10 38.3 6.7 4.4 8.2 0.0 10.4 11 0 0 11 11 11 1 Ankyrin repeat DUF5049 PF16468.5 RLN91440.1 - 8.1e-05 22.4 0.5 1.4 8.9 0.0 5.5 6 1 1 7 7 7 2 Domain of unknown function (DUF5049) FAD-oxidase_C PF02913.19 RLN91441.1 - 3e-43 148.3 0.1 1.2e-42 146.3 0.0 1.8 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 RLN91441.1 - 1.3e-37 128.6 0.1 2.8e-37 127.6 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain IU_nuc_hydro PF01156.19 RLN91441.1 - 0.022 14.3 0.0 0.59 9.7 0.0 2.2 2 0 0 2 2 2 0 Inosine-uridine preferring nucleoside hydrolase NINJA_B PF16136.5 RLN91442.1 - 0.0025 18.2 6.5 0.0057 17.0 6.5 1.7 1 0 0 1 1 1 1 Putative nuclear localisation signal Peptidase_S64 PF08192.11 RLN91442.1 - 3.7 5.9 8.8 6 5.2 8.8 1.3 1 0 0 1 1 1 0 Peptidase family S64 DUF4407 PF14362.6 RLN91442.1 - 7.1 5.9 8.7 0.37 10.1 3.6 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Asp PF00026.23 RLN91444.1 - 4.9e-63 213.5 0.0 7.2e-63 212.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RLN91444.1 - 7.2e-14 52.4 0.1 4.4e-06 27.1 0.1 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 RLN91444.1 - 0.00044 20.0 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal 2-oxoacid_dh PF00198.23 RLN91447.1 - 1.7e-17 63.6 0.0 2.2e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 RLN91447.1 - 5e-14 51.9 0.8 1.1e-13 50.8 0.8 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 RLN91447.1 - 1.5e-13 50.8 0.3 6.4e-13 48.8 0.3 2.2 1 0 0 1 1 1 1 e3 binding domain HlyD_3 PF13437.6 RLN91447.1 - 0.031 15.0 4.5 0.094 13.4 0.1 3.2 2 2 1 3 3 3 0 HlyD family secretion protein DUF515 PF04415.12 RLN91447.1 - 0.083 11.3 0.1 0.12 10.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) LPMO_10 PF03067.15 RLN91449.1 - 1.9e-07 31.9 0.1 4.6e-07 30.7 0.1 1.6 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 RLN91450.1 - 0.0063 16.5 0.5 1.6 8.6 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 61 RNA_pol_Rpc4 PF05132.14 RLN91450.1 - 0.07 13.6 0.5 0.1 13.0 0.5 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC27 PF09507.10 RLN91450.1 - 0.32 10.3 7.1 0.45 9.8 7.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NeA_P2 PF12312.8 RLN91452.1 - 0.59 9.5 4.1 0.11 11.9 0.3 1.6 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein DUF2408 PF10303.9 RLN91452.1 - 6.5 7.3 8.9 5.3 7.6 4.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) TFIIA PF03153.13 RLN91453.1 - 0.68 9.9 10.3 1.2 9.1 10.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LPMO_10 PF03067.15 RLN91454.1 - 9.3e-09 36.2 0.1 3e-08 34.6 0.1 1.7 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading SOG2 PF10428.9 RLN91456.1 - 9.7 5.3 25.3 13 4.8 25.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Med13_C PF06333.12 RLN91457.1 - 7.5 5.7 24.6 15 4.7 24.6 1.5 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain TGase_elicitor PF16683.5 RLN91462.1 - 0.026 13.3 0.0 0.039 12.7 0.0 1.1 1 0 0 1 1 1 0 Transglutaminase elicitor DUF3040 PF11239.8 RLN91462.1 - 0.055 13.8 14.4 0.14 12.5 11.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Pro_CA PF00484.19 RLN91465.1 - 2.8e-06 27.7 0.0 4.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase Ras PF00071.22 RLN91466.1 - 9e-25 87.1 0.4 1.1e-24 86.9 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN91466.1 - 0.00089 19.5 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase CENP-M PF11111.8 RLN91466.1 - 0.021 14.0 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) Pro_CA PF00484.19 RLN91467.1 - 1.2e-43 149.1 0.4 2.1e-42 145.0 0.4 2.1 1 1 0 1 1 1 1 Carbonic anhydrase Vps51 PF08700.11 RLN91468.1 - 1.5e-10 41.0 0.7 7.3e-10 38.8 0.7 2.2 1 0 0 1 1 1 1 Vps51/Vps67 PH PF00169.29 RLN91468.1 - 7.8e-10 39.2 1.0 1.4e-08 35.2 0.1 2.5 2 0 0 2 2 2 1 PH domain Exo84_C PF16528.5 RLN91468.1 - 4.5e-09 36.4 1.5 4.5e-09 36.4 1.5 2.4 2 0 0 2 2 2 1 Exocyst component 84 C-terminal EF-hand_4 PF12763.7 RLN91468.1 - 7.4e-06 25.9 0.0 9.4e-05 22.3 0.0 2.6 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 RLN91468.1 - 9.6e-06 26.0 0.0 0.00023 21.5 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN91468.1 - 1e-05 24.7 0.0 0.26 10.9 0.0 3.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN91468.1 - 0.0017 18.1 0.0 1.5 9.0 0.1 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 RLN91468.1 - 0.028 13.9 0.4 0.38 10.3 0.4 2.8 2 0 0 2 2 2 0 EF hand PH_6 PF15406.6 RLN91468.1 - 0.029 14.7 0.1 0.078 13.3 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain SVA PF05326.11 RLN91468.1 - 0.1 12.6 0.0 0.85 9.6 0.0 2.2 2 0 0 2 2 2 0 Seminal vesicle autoantigen (SVA) COG5 PF10392.9 RLN91468.1 - 0.19 11.9 3.8 0.13 12.4 0.4 2.5 2 0 0 2 2 2 0 Golgi transport complex subunit 5 RCC1 PF00415.18 RLN91469.1 - 1.9e-48 162.8 10.3 6.3e-12 45.9 0.1 5.6 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN91469.1 - 8.1e-22 76.5 19.4 3.3e-09 36.3 0.2 4.8 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.29 RLN91469.1 - 2.4e-06 27.3 9.3 5.6e-06 26.1 9.3 1.6 1 1 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 RLN91469.1 - 0.062 13.2 9.2 0.11 12.5 9.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 G8 PF10162.9 RLN91470.1 - 8e-11 42.1 0.0 2.4e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 G8 domain Beta_helix PF13229.6 RLN91470.1 - 5.9e-08 32.7 0.3 1.2e-05 25.2 0.0 3.5 3 1 0 3 3 3 1 Right handed beta helix region PapC_C PF13953.6 RLN91470.1 - 0.08 12.8 0.2 16 5.4 0.0 2.9 2 0 0 2 2 2 0 PapC C-terminal domain NosD PF05048.13 RLN91470.1 - 0.2 10.9 2.6 0.35 10.1 0.1 2.4 3 1 0 3 3 3 0 Periplasmic copper-binding protein (NosD) Dimer_Tnp_hAT PF05699.14 RLN91471.1 - 4.5e-10 39.2 0.1 1.1e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 RLN91471.1 - 1e-06 28.6 0.3 1e-06 28.6 0.3 2.0 2 0 0 2 2 2 1 BED zinc finger TetR_C_33 PF13305.6 RLN91471.1 - 0.018 15.8 0.2 0.32 11.7 0.2 3.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain RWP-RK PF02042.15 RLN91472.1 - 1.1e-13 50.9 0.0 2.4e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain Sigma70_r4_2 PF08281.12 RLN91472.1 - 0.0012 18.5 0.1 0.0055 16.3 0.1 1.9 1 1 1 2 2 2 2 Sigma-70, region 4 HTH_50 PF18024.1 RLN91472.1 - 0.017 14.7 0.1 0.038 13.6 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_6 PF01418.17 RLN91472.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family TnsD PF15978.5 RLN91472.1 - 0.073 12.1 0.2 0.094 11.7 0.2 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_38 PF13936.6 RLN91472.1 - 0.075 12.8 1.0 0.12 12.1 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 RLN91472.1 - 0.12 12.6 0.2 11 6.3 0.1 2.9 1 1 2 3 3 3 0 Helix-turn-helix domain Cas9_a PF18470.1 RLN91473.1 - 0.031 13.8 0.2 0.066 12.7 0.2 1.5 1 0 0 1 1 1 0 Cas9 alpha-helical lobe domain RIB43A PF05914.12 RLN91474.1 - 6.2e-16 58.1 16.9 6.8e-16 58.0 16.9 1.0 1 0 0 1 1 1 1 RIB43A MFAP1 PF06991.11 RLN91474.1 - 0.014 15.2 10.1 0.019 14.8 10.1 1.2 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing Sec62 PF03839.16 RLN91474.1 - 2.1 7.8 3.8 2.4 7.6 3.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 RNase_H PF00075.24 RLN91475.1 - 1e-22 80.9 0.3 1.4e-22 80.4 0.3 1.2 1 0 0 1 1 1 1 RNase H Phage_C PF12025.8 RLN91475.1 - 0.04 13.8 0.2 1.1 9.1 0.2 2.4 1 1 0 1 1 1 0 Phage protein C PTA_PTB PF01515.19 RLN91477.1 - 1e-113 379.9 0.4 1.5e-113 379.4 0.4 1.2 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase AAA_26 PF13500.6 RLN91477.1 - 1.1e-17 64.5 0.0 1.9e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DRTGG PF07085.12 RLN91477.1 - 2.3e-15 56.3 0.1 9.7e-15 54.3 0.1 2.2 2 0 0 2 2 2 1 DRTGG domain BAR PF03114.18 RLN91478.1 - 0.014 15.1 0.9 0.017 14.7 0.9 1.1 1 0 0 1 1 1 0 BAR domain FAM92 PF06730.11 RLN91478.1 - 0.037 13.5 0.2 0.057 12.8 0.2 1.3 1 0 0 1 1 1 0 FAM92 protein PUF PF00806.19 RLN91479.1 - 3e-11 42.4 0.0 0.012 15.2 0.0 5.6 6 0 0 6 6 6 3 Pumilio-family RNA binding repeat DUF4192 PF13830.6 RLN91479.1 - 0.97 9.4 8.2 0.11 12.5 2.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4192) DUF2052 PF09747.9 RLN91479.1 - 1.1 9.3 16.7 7.1 6.7 0.2 2.7 2 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) TRAP_alpha PF03896.16 RLN91479.1 - 2 7.5 7.9 9.3 5.4 0.3 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit CDT1_C PF16679.5 RLN91479.1 - 3.4 8.2 7.2 1.7 9.2 2.3 3.0 2 1 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain Carb_anhydrase PF00194.21 RLN91480.1 - 1.5e-38 132.8 0.0 2.3e-38 132.2 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase TRAP_alpha PF03896.16 RLN91481.1 - 5.2 6.2 8.7 5.5 6.1 8.7 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BT1 PF03092.16 RLN91483.1 - 3.7e-13 48.5 15.1 2.2e-11 42.7 1.0 3.2 2 1 1 3 3 3 3 BT1 family Glyco_hydro_92 PF07971.12 RLN91483.1 - 0.21 10.5 0.3 0.31 9.9 0.3 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 DEAD PF00270.29 RLN91484.1 - 3.8e-06 26.8 0.4 0.014 15.2 0.1 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN91484.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.8 1 1 0 1 1 1 0 Helicase conserved C-terminal domain CBS PF00571.28 RLN91484.1 - 0.057 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 CBS domain DUF5600 PF18150.1 RLN91488.1 - 5.9e-24 84.7 0.0 1.3e-23 83.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 RLN91488.1 - 0.0074 16.2 0.0 0.025 14.5 0.0 1.9 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand RNA_helicase PF00910.22 RLN91488.1 - 0.18 12.2 0.0 0.68 10.3 0.0 1.9 2 0 0 2 2 2 0 RNA helicase EmrE PF13536.6 RLN91488.1 - 0.24 11.0 0.0 0.38 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative multidrug resistance efflux transporter DUF2188 PF09954.9 RLN91488.1 - 0.27 11.4 2.8 32 4.8 0.1 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2188) FYVE_2 PF02318.16 RLN91490.1 - 0.14 12.4 4.5 0.24 11.6 4.5 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Myb_DNA-bind_4 PF13837.6 RLN91492.1 - 0.0029 18.0 0.9 0.031 14.6 0.0 2.7 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain adh_short PF00106.25 RLN91493.1 - 5.8e-48 162.9 0.3 8.4e-48 162.4 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN91493.1 - 6.7e-32 110.9 1.2 7.9e-32 110.7 0.2 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN91493.1 - 7.2e-17 61.9 0.1 1e-16 61.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN91493.1 - 0.052 13.0 0.1 0.1 12.1 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF111 PF01969.17 RLN91494.1 - 1.6e-86 290.8 0.9 1.9e-80 270.8 0.1 2.0 2 0 0 2 2 2 2 Protein of unknown function DUF111 DDE_1 PF03184.19 RLN91496.1 - 8.5e-33 113.4 0.0 2e-32 112.2 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN91496.1 - 9.9e-11 41.5 0.1 1.9e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Rhomboid PF01694.22 RLN91497.1 - 3.9e-12 46.4 0.4 1.6e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 Rhomboid family Arm PF00514.23 RLN91498.1 - 7.6e-79 257.6 19.1 3.5e-13 49.1 0.0 8.9 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN91498.1 - 1.5e-17 63.7 9.7 1.2e-05 25.7 0.0 6.7 5 2 3 8 8 7 4 HEAT-like repeat Arm_3 PF16186.5 RLN91498.1 - 1.2e-16 60.0 6.3 2.9e-16 58.8 3.3 2.3 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 RLN91498.1 - 1.1e-15 57.8 0.9 2.6e-05 24.5 0.0 5.5 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.22 RLN91498.1 - 1.2e-11 43.8 7.3 0.2 12.0 0.0 7.8 9 0 0 9 9 9 3 HEAT repeat IBB PF01749.20 RLN91498.1 - 1.3e-09 38.4 8.4 7.7e-09 35.9 8.4 2.2 1 1 0 1 1 1 1 Importin beta binding domain V-ATPase_H_C PF11698.8 RLN91498.1 - 0.0014 18.7 0.8 8 6.6 0.0 4.5 3 3 2 5 5 5 2 V-ATPase subunit H Cnd1 PF12717.7 RLN91498.1 - 0.025 14.6 3.5 0.22 11.5 0.3 3.6 3 1 2 5 5 5 0 non-SMC mitotic condensation complex subunit 1 CTNNBL PF08216.11 RLN91498.1 - 0.03 14.5 0.2 52 4.1 0.0 4.1 3 1 1 4 4 4 0 Catenin-beta-like, Arm-motif containing nuclear CLASP_N PF12348.8 RLN91498.1 - 0.038 13.5 1.5 0.06 12.9 0.2 1.8 2 0 0 2 2 2 0 CLASP N terminal Mo25 PF08569.11 RLN91498.1 - 0.044 13.2 0.1 0.2 11.0 0.0 2.1 2 0 0 2 2 2 0 Mo25-like DUF3361 PF11841.8 RLN91498.1 - 0.053 13.5 4.8 3.5 7.6 0.0 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF3361) Myosin_head PF00063.21 RLN91499.1 - 1.2e-215 717.8 0.0 1.8e-215 717.2 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Aida_C2 PF14186.6 RLN91499.1 - 2.9e-31 108.1 0.0 3.4e-16 59.2 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal adhesion Ank_2 PF12796.7 RLN91499.1 - 1.6e-19 70.3 0.7 4.6e-08 33.5 0.3 3.1 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) IQ PF00612.27 RLN91499.1 - 2.4e-16 57.9 105.6 0.0018 17.9 0.9 16.2 17 0 0 17 17 17 9 IQ calmodulin-binding motif Ank_4 PF13637.6 RLN91499.1 - 3.8e-16 59.2 0.2 9.1e-08 32.5 0.0 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN91499.1 - 4.2e-16 58.8 1.7 7.6e-07 29.3 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN91499.1 - 3.9e-15 54.4 0.1 0.0043 17.4 0.1 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 RLN91499.1 - 5e-14 52.0 0.2 0.0056 17.1 0.2 4.2 4 0 0 4 4 3 3 Ankyrin repeat PH PF00169.29 RLN91499.1 - 8.5e-14 51.9 0.1 2.5e-13 50.5 0.1 1.9 1 0 0 1 1 1 1 PH domain AAA_16 PF13191.6 RLN91499.1 - 0.17 12.2 1.4 0.38 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain PH_11 PF15413.6 RLN91499.1 - 0.23 11.9 1.4 1.5 9.3 0.2 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain Brix PF04427.18 RLN91500.1 - 1.4e-26 93.8 0.0 2e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain Cleaved_Adhesin PF07675.11 RLN91500.1 - 0.21 11.5 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 Cleaved Adhesin Domain tRNA_m1G_MT PF01746.21 RLN91501.1 - 2.1e-13 50.4 0.1 2.1e-13 50.4 0.1 1.5 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase Vta1 PF04652.16 RLN91502.1 - 1.4e-22 80.2 0.0 2.1e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Vta1 like Trypsin_2 PF13365.6 RLN91502.1 - 1.8e-19 71.1 0.0 3.2e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 RLN91502.1 - 7.6e-15 55.0 0.1 1.7e-14 53.9 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RLN91502.1 - 5.4e-12 45.4 0.0 1.2e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 RLN91502.1 - 2.8e-11 43.7 0.0 4.1e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Trypsin PDZ PF00595.24 RLN91502.1 - 2.1e-07 31.2 0.0 7.1e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 PDZ domain Peptidase_S7 PF00949.21 RLN91502.1 - 0.0056 16.5 0.7 0.011 15.6 0.7 1.4 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.9 RLN91502.1 - 0.031 12.9 0.3 0.047 12.3 0.3 1.2 1 0 0 1 1 1 0 Peptidase S46 Tricorn_PDZ PF14685.6 RLN91502.1 - 0.036 14.0 0.1 0.075 13.0 0.1 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain DUF31 PF01732.16 RLN91502.1 - 0.12 11.9 0.5 0.2 11.2 0.5 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) Metallophos PF00149.28 RLN91503.1 - 3.4e-24 86.5 0.0 6.1e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RLN91503.1 - 0.00096 19.5 1.9 0.0013 19.1 0.3 2.1 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Trs65 PF12735.7 RLN91503.1 - 0.093 12.1 0.0 0.4 10.0 0.0 1.8 1 1 0 1 1 1 0 TRAPP trafficking subunit Trs65 ATG27 PF09451.10 RLN91503.1 - 0.19 11.6 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 Autophagy-related protein 27 FAT PF02259.23 RLN91504.1 - 2.9e-35 122.1 9.0 2.9e-35 122.1 9.0 1.9 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 RLN91504.1 - 4.6e-23 82.3 0.0 1.5e-22 80.6 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 RLN91504.1 - 0.035 13.9 0.0 0.1 12.4 0.0 1.9 1 0 0 1 1 1 0 FATC domain Cnd3 PF12719.7 RLN91504.1 - 0.044 13.0 2.2 17 4.5 0.0 4.7 5 0 0 5 5 5 0 Nuclear condensing complex subunits, C-term domain DUF1160 PF06648.11 RLN91504.1 - 0.099 12.6 0.1 0.29 11.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) GlcNAc PF11397.8 RLN91505.1 - 2.4e-16 60.1 0.0 3.1e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) CBM_25 PF03423.13 RLN91506.1 - 1e-24 86.8 29.5 6.7e-14 52.0 7.3 3.1 2 1 1 3 3 3 2 Carbohydrate binding domain (family 25) CBM53 PF16760.5 RLN91506.1 - 2.3e-22 79.3 11.8 2e-11 44.3 1.8 2.7 2 0 0 2 2 2 2 Starch/carbohydrate-binding module (family 53) Alpha-amylase PF00128.24 RLN91506.1 - 8.1e-09 35.5 0.0 1.6e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CBM26 PF16738.5 RLN91506.1 - 0.0001 22.5 11.5 0.054 13.8 2.8 3.1 2 0 0 2 2 2 2 Starch-binding module 26 CBM_21 PF03370.13 RLN91506.1 - 0.69 10.1 8.2 3.4 7.9 0.6 2.5 2 0 0 2 2 2 0 Carbohydrate/starch-binding module (family 21) Proteasom_PSMB PF10508.9 RLN91507.1 - 2e-16 59.6 0.0 2.8e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit FHA PF00498.26 RLN91507.1 - 3.7e-06 27.2 0.1 8.2e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RLN91507.1 - 0.0097 16.2 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain ABC2_membrane PF01061.24 RLN91509.1 - 3.4e-33 114.8 30.4 6.2e-33 114.0 30.4 1.4 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN91509.1 - 3.5e-05 23.6 1.0 0.00014 21.7 0.0 2.5 3 0 0 3 3 3 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 RLN91509.1 - 0.00042 19.5 19.8 0.00042 19.5 19.8 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 RLN91509.1 - 0.014 15.2 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system PDR_assoc PF08370.11 RLN91509.1 - 7.6 6.4 7.1 2.3 8.0 0.1 3.2 3 0 0 3 3 3 0 Plant PDR ABC transporter associated ABC2_membrane PF01061.24 RLN91510.1 - 8.2e-69 231.2 77.2 7.6e-38 130.0 26.4 2.6 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN91510.1 - 8.4e-35 120.3 0.1 2.1e-16 60.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 RLN91510.1 - 3.7e-08 32.9 58.1 2.3e-05 23.7 22.7 3.2 2 1 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 RLN91510.1 - 5.8e-08 32.8 0.9 0.0077 16.1 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 RLN91510.1 - 6.4e-08 33.2 0.2 0.006 17.0 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 RLN91510.1 - 2.1e-07 31.1 1.6 0.071 12.9 0.0 3.6 4 0 0 4 4 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN91510.1 - 1.1e-05 25.0 6.2 0.02 14.6 1.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN91510.1 - 1.5e-05 24.6 0.2 0.053 13.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RLN91510.1 - 3.7e-05 24.0 0.0 0.081 13.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN91510.1 - 0.00015 21.1 0.9 0.016 14.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.6 RLN91510.1 - 0.00066 20.2 0.7 0.32 11.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RLN91510.1 - 0.0021 18.5 0.2 5.5 7.4 0.2 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 RLN91510.1 - 0.0031 17.0 0.8 4.9 6.5 0.1 3.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 RLN91510.1 - 0.0033 17.2 0.2 0.95 9.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain PDR_CDR PF06422.12 RLN91510.1 - 0.0039 17.1 0.0 0.0039 17.1 0.0 4.3 5 1 1 6 6 4 1 CDR ABC transporter cobW PF02492.19 RLN91510.1 - 0.0052 16.4 1.7 1.1 8.8 0.4 2.6 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain PDR_assoc PF08370.11 RLN91510.1 - 0.0063 16.2 12.2 0.036 13.8 1.5 4.0 3 0 0 3 3 3 1 Plant PDR ABC transporter associated AAA_18 PF13238.6 RLN91510.1 - 0.0067 17.0 0.0 4.9 7.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 RLN91510.1 - 0.0083 16.2 2.9 1 9.4 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase ABC_ATPase PF09818.9 RLN91510.1 - 0.0095 14.8 0.8 1.4 7.6 0.0 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_24 PF13479.6 RLN91510.1 - 0.016 14.9 1.4 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 RLN91510.1 - 0.019 15.0 0.5 0.81 9.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 RLN91510.1 - 0.023 14.9 0.1 6.4 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 RLN91510.1 - 0.028 13.6 0.1 0.14 11.3 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit DUF815 PF05673.13 RLN91510.1 - 0.029 13.5 0.2 0.077 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Roc PF08477.13 RLN91510.1 - 0.034 14.3 0.5 2.8 8.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 RLN91510.1 - 0.064 13.2 4.2 3.8 7.4 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 RLN91510.1 - 0.074 13.4 0.2 17 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 RLN91510.1 - 0.085 12.6 1.8 4.1 7.2 0.3 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 RLN91510.1 - 0.093 12.7 1.1 3.3 7.7 0.2 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ploopntkinase3 PF18751.1 RLN91510.1 - 0.16 11.8 0.2 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 RLN91510.1 - 1.3 9.2 3.8 48 4.1 1.6 2.7 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 RLN91510.1 - 8.8 6.4 5.2 6.8 6.7 0.1 2.6 3 0 0 3 3 2 0 Dynamin family PDR_CDR PF06422.12 RLN91511.1 - 1.2e-09 37.9 0.0 1.8e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 CDR ABC transporter PDR_assoc PF08370.11 RLN91511.1 - 0.0011 18.6 0.3 0.0011 18.6 0.3 1.8 2 1 0 2 2 2 1 Plant PDR ABC transporter associated TRAM_LAG1_CLN8 PF03798.16 RLN91512.1 - 2e-26 93.0 26.3 2.9e-26 92.4 26.3 1.3 1 0 0 1 1 1 1 TLC domain FUN14 PF04930.15 RLN91513.1 - 1.3e-25 89.6 0.6 2e-25 89.0 0.6 1.3 1 0 0 1 1 1 1 FUN14 family EF-hand_1 PF00036.32 RLN91513.1 - 2.1e-05 23.7 0.8 3.9e-05 22.9 0.1 1.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RLN91513.1 - 0.0027 17.5 0.1 0.008 16.0 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 RLN91513.1 - 0.018 14.5 0.7 0.036 13.6 0.7 1.4 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 RLN91513.1 - 0.099 13.1 0.0 0.48 10.9 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain pair SDF PF00375.18 RLN91514.1 - 5e-72 243.1 30.8 2.1e-71 241.0 30.8 1.7 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family AbiEi_4 PF13338.6 RLN91515.1 - 0.0043 17.2 0.6 0.13 12.4 0.6 2.6 1 1 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin Mago-bind PF09282.10 RLN91516.1 - 3.5e-13 49.1 3.0 6.8e-13 48.2 3.0 1.5 1 0 0 1 1 1 1 Mago binding Cwf_Cwc_15 PF04889.12 RLN91516.1 - 0.026 14.2 1.9 0.03 14.0 1.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3138 PF11336.8 RLN91516.1 - 0.96 8.0 4.6 1.3 7.6 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) zf_CCCH_4 PF18345.1 RLN91517.1 - 0.013 15.5 1.3 0.029 14.4 1.3 1.6 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH PF00642.24 RLN91517.1 - 0.014 15.3 2.3 0.027 14.4 2.3 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PQQ PF01011.21 RLN91517.1 - 0.037 14.0 0.0 0.089 12.8 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat RPN2_C PF18004.1 RLN91517.1 - 0.04 13.8 11.3 0.062 13.2 11.3 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain SL4P PF17618.2 RLN91517.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein FmiP_Thoc5 PF09766.9 RLN91517.1 - 0.087 12.1 3.4 0.12 11.6 3.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 FancD2 PF14631.6 RLN91517.1 - 0.25 8.7 2.1 0.29 8.5 2.1 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease NPR3 PF03666.13 RLN91517.1 - 0.73 8.5 6.3 0.96 8.2 6.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pyr_redox_2 PF07992.14 RLN91519.1 - 1.5e-12 47.3 0.3 3.9e-11 42.7 0.3 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 RLN91519.1 - 8.8e-06 25.8 0.5 0.0015 18.6 0.1 2.5 1 1 1 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 RLN91519.1 - 2.3e-05 24.5 0.1 0.00029 21.0 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RLN91519.1 - 0.0002 21.1 0.5 0.00048 19.8 0.2 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 RLN91519.1 - 0.00025 20.4 1.0 0.00043 19.6 0.3 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 RLN91519.1 - 0.00048 19.1 0.1 0.00074 18.5 0.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase HI0933_like PF03486.14 RLN91519.1 - 0.00058 18.7 0.3 0.0018 17.1 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 RLN91519.1 - 0.0019 17.5 0.3 0.0069 15.7 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 RLN91519.1 - 0.0029 16.9 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 RLN91519.1 - 0.0089 16.6 1.6 0.16 12.5 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RLN91519.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 RLN91519.1 - 0.018 14.1 0.2 0.029 13.5 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Methyltransf_34 PF11312.8 RLN91519.1 - 0.11 11.7 1.1 0.27 10.5 0.1 1.9 2 1 0 2 2 2 0 Putative SAM-dependent methyltransferase Minor_tail_Z PF06763.11 RLN91521.1 - 0.041 13.7 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Prophage minor tail protein Z (GPZ) DNA_pol_A_exo1 PF01612.20 RLN91522.1 - 3.4e-05 23.6 0.1 0.14 11.8 0.0 2.3 2 0 0 2 2 2 2 3'-5' exonuclease AAA_16 PF13191.6 RLN91522.1 - 3.4e-05 24.3 0.0 0.0001 22.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 RLN91522.1 - 0.00023 21.0 0.0 0.00045 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 RLN91522.1 - 0.00055 20.4 0.0 0.002 18.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 RLN91522.1 - 0.00087 19.1 0.1 0.0026 17.5 0.0 1.9 2 0 0 2 2 1 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 RLN91522.1 - 0.0014 19.0 0.2 0.011 16.1 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RLN91522.1 - 0.0016 18.2 0.0 0.0055 16.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 RLN91522.1 - 0.0021 17.3 0.0 0.0035 16.6 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain NTPase_1 PF03266.15 RLN91522.1 - 0.0031 17.4 0.3 0.26 11.2 0.0 2.4 2 0 0 2 2 2 1 NTPase AAA_33 PF13671.6 RLN91522.1 - 0.0038 17.4 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 RLN91522.1 - 0.0043 16.1 0.1 0.0088 15.1 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 RLN91522.1 - 0.008 16.7 0.0 0.041 14.4 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 RLN91522.1 - 0.021 15.1 0.4 0.17 12.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 RLN91522.1 - 0.021 14.7 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 RLN91522.1 - 0.024 14.2 0.4 0.42 10.2 0.0 3.0 4 0 0 4 4 4 0 AAA domain Phage_lysis PF03245.13 RLN91522.1 - 0.024 14.7 0.3 0.17 12.0 0.2 2.3 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein MeaB PF03308.16 RLN91522.1 - 0.033 13.2 0.0 0.078 11.9 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 RLN91522.1 - 0.034 13.4 0.0 0.064 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 RLN91522.1 - 0.037 13.5 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 RLN91522.1 - 0.039 13.5 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 RLN91522.1 - 0.04 13.3 0.1 6.1 6.2 0.0 2.6 2 0 0 2 2 2 0 Bacterial TniB protein DLIC PF05783.11 RLN91522.1 - 0.043 12.7 0.0 0.11 11.4 0.0 1.6 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_5 PF07728.14 RLN91522.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) STI1 PF17830.1 RLN91522.1 - 0.053 13.4 0.0 19 5.3 0.0 3.2 3 0 0 3 3 3 0 STI1 domain KTI12 PF08433.10 RLN91522.1 - 0.054 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 RLN91522.1 - 0.055 14.0 0.0 0.24 11.9 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 RLN91522.1 - 0.085 12.7 0.0 0.41 10.5 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 RLN91522.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 RLN91522.1 - 0.12 12.2 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.9 RLN91522.1 - 0.12 11.3 0.1 0.31 9.9 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.22 RLN91522.1 - 0.12 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 RLN91522.1 - 0.14 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 RLN91522.1 - 0.17 12.3 0.0 1.4 9.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase MORN PF02493.20 RLN91523.1 - 3.9e-25 86.2 21.1 4.2e-05 23.2 0.3 8.1 7 0 0 7 7 7 6 MORN repeat WW PF00397.26 RLN91523.1 - 3.6e-11 42.9 3.1 1.6e-08 34.5 0.6 3.0 2 0 0 2 2 2 2 WW domain IQ PF00612.27 RLN91523.1 - 2e-10 39.5 59.8 0.0012 18.5 2.2 9.8 9 0 0 9 9 9 6 IQ calmodulin-binding motif LRR_4 PF12799.7 RLN91523.1 - 1.8e-07 31.4 15.4 0.19 12.2 0.7 7.7 8 1 1 9 9 9 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RLN91523.1 - 2.5e-06 27.1 18.4 3.1 8.1 0.4 9.6 10 0 0 10 10 10 2 Leucine Rich repeat OST-HTH PF12872.7 RLN91523.1 - 0.0048 16.7 0.0 0.017 14.9 0.0 2.0 1 0 0 1 1 1 1 OST-HTH/LOTUS domain LRR_1 PF00560.33 RLN91523.1 - 0.13 12.9 18.7 31 5.7 0.5 8.7 9 1 0 9 9 9 0 Leucine Rich Repeat TUDOR PF00567.24 RLN91523.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Tudor domain zf-C2H2_jaz PF12171.8 RLN91523.1 - 0.15 12.4 0.0 4.2 7.8 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding EamA PF00892.20 RLN91525.1 - 8.9e-13 48.6 21.9 1.3e-08 35.1 3.0 2.5 2 0 0 2 2 2 2 EamA-like transporter family NTP_transf_3 PF12804.7 RLN91525.1 - 6.5e-09 36.3 0.2 1.4e-08 35.3 0.2 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 RLN91525.1 - 0.017 14.7 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase ADH_zinc_N_2 PF13602.6 RLN91526.1 - 1.9e-18 67.8 0.0 3.1e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN91526.1 - 1.1e-05 25.3 0.5 0.0002 21.2 0.3 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain MS_channel PF00924.18 RLN91527.1 - 1.8e-29 102.8 0.1 3.2e-29 101.9 0.1 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel Arv1 PF04161.13 RLN91527.1 - 6 7.0 10.3 3.4 7.8 7.7 1.8 1 1 1 2 2 2 0 Arv1-like family RabGAP-TBC PF00566.18 RLN91528.1 - 2.5e-12 46.9 0.0 4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH PF00169.29 RLN91529.1 - 3.4e-08 33.9 3.4 0.0044 17.5 0.0 3.2 1 1 1 3 3 3 2 PH domain PH_8 PF15409.6 RLN91529.1 - 0.0016 18.7 0.8 0.032 14.5 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain MLVIN_C PF18697.1 RLN91529.1 - 0.11 12.7 2.4 3.3 7.9 0.1 2.8 3 0 0 3 3 3 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain PH_11 PF15413.6 RLN91529.1 - 0.21 12.0 3.6 4.5 7.8 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain Cep57_MT_bd PF06657.13 RLN91532.1 - 1.2 9.6 8.5 0.088 13.3 0.8 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 MCU PF04678.13 RLN91532.1 - 5 7.2 12.2 9.9 6.2 9.7 2.7 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Meiosis_expr PF15163.6 RLN91533.1 - 9.8e-29 99.8 4.7 1.3e-28 99.4 4.7 1.2 1 0 0 1 1 1 1 Meiosis-expressed SAC3_GANP PF03399.16 RLN91534.1 - 3e-56 191.0 0.0 3.7e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP family Heme_oxygenase PF01126.20 RLN91534.1 - 2e-14 53.9 0.1 1.5e-13 51.0 0.0 2.2 2 0 0 2 2 2 1 Heme oxygenase Myb_DNA-binding PF00249.31 RLN91535.1 - 5.8e-33 112.8 3.4 1.5e-09 37.9 0.0 4.7 4 0 0 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN91535.1 - 1.1e-26 92.8 0.0 1.7e-09 37.7 0.0 4.6 2 2 2 4 4 4 4 Myb-like DNA-binding domain SLIDE PF09111.10 RLN91535.1 - 0.1 12.6 0.0 1.5 8.9 0.0 2.7 1 1 1 2 2 2 0 SLIDE TPR_2 PF07719.17 RLN91537.1 - 8e-08 31.8 11.1 0.026 14.6 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN91537.1 - 7.9e-07 29.0 1.6 0.014 15.7 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN91537.1 - 8.9e-06 25.3 4.0 1.1 9.2 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 RLN91537.1 - 0.00017 22.0 1.8 0.065 13.9 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN91537.1 - 0.00018 22.1 14.4 0.0033 18.0 4.3 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN91537.1 - 0.00071 19.2 9.3 0.24 11.1 0.9 4.2 3 1 1 4 4 4 2 TPR repeat TPR_9 PF13371.6 RLN91537.1 - 0.00077 19.6 7.6 0.0036 17.4 3.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN91537.1 - 0.0018 18.4 2.7 18 5.8 0.9 4.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN91537.1 - 0.0021 18.7 13.0 0.039 14.8 1.5 3.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN91537.1 - 0.0039 17.7 16.2 0.0046 17.4 6.8 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Rax2 PF12768.7 RLN91537.1 - 0.028 13.9 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity TPR_7 PF13176.6 RLN91537.1 - 0.034 14.2 5.0 11 6.3 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF4337 PF14235.6 RLN91537.1 - 0.06 13.5 0.3 0.12 12.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4366 PF14283.6 RLN91537.1 - 0.22 11.5 0.4 1.7 8.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) TPR_4 PF07721.14 RLN91537.1 - 2.7 8.9 14.9 3 8.7 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat LRR_8 PF13855.6 RLN91539.1 - 1.7e-21 75.7 5.3 2.6e-12 46.3 1.9 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RLN91539.1 - 1.1e-12 48.0 0.6 2.4e-06 27.8 0.5 2.6 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN91539.1 - 3.3e-05 23.8 0.2 1.2 9.9 0.1 4.3 3 1 1 4 4 4 1 Leucine Rich Repeat LRR_9 PF14580.6 RLN91539.1 - 0.00067 19.2 1.0 0.00094 18.7 1.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat Cas6 PF09559.10 RLN91539.1 - 0.13 12.2 1.1 0.18 11.8 1.1 1.3 1 0 0 1 1 1 0 Cas6 Crispr Arm PF00514.23 RLN91540.1 - 0.00017 21.5 19.8 12 6.2 0.1 10.1 10 0 0 10 10 10 3 Armadillo/beta-catenin-like repeat PUL PF08324.11 RLN91540.1 - 0.0033 16.7 1.8 0.021 14.0 0.2 2.7 2 0 0 2 2 2 1 PUL domain KAP PF05804.12 RLN91540.1 - 0.0049 15.1 0.1 0.048 11.8 0.1 2.0 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) Arm_2 PF04826.13 RLN91540.1 - 0.14 11.6 0.0 60 3.0 0.0 3.1 3 0 0 3 3 3 0 Armadillo-like MPS2 PF17060.5 RLN91542.1 - 0.03 13.6 2.6 0.047 13.0 2.6 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 SAGA-Tad1 PF12767.7 RLN91542.1 - 0.16 11.7 5.3 0.26 11.0 5.3 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit CIAPIN1 PF05093.13 RLN91542.1 - 0.46 11.0 3.5 1.2 9.7 3.5 1.7 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Syntaxin_2 PF14523.6 RLN91542.1 - 0.5 10.8 6.7 1.4 9.3 4.3 2.5 2 0 0 2 2 2 0 Syntaxin-like protein MRPL52 PF18699.1 RLN91542.1 - 4.1 7.7 10.2 4.5 7.5 3.2 2.6 1 1 1 2 2 2 0 Mitoribosomal protein mL52 Cor1 PF04803.12 RLN91542.1 - 4.2 7.6 12.3 0.52 10.5 7.2 2.0 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region DUF2690 PF10901.8 RLN91543.1 - 0.018 15.3 1.4 0.98 9.8 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2690) Diphthamide_syn PF01866.17 RLN91544.1 - 1.7e-26 93.4 6.7 4.7e-25 88.6 6.6 2.1 1 1 0 1 1 1 1 Putative diphthamide synthesis protein Lipoprotein_7 PF01540.16 RLN91544.1 - 0.055 12.8 0.0 0.073 12.4 0.0 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein Diphthamide_syn PF01866.17 RLN91545.1 - 7.5e-53 179.9 0.0 8.5e-53 179.8 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Pkinase PF00069.25 RLN91546.1 - 2.5e-39 135.2 0.0 3e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN91546.1 - 4e-14 52.5 0.0 5.5e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RLN91546.1 - 0.15 11.0 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain bZIP_1 PF00170.21 RLN91547.1 - 0.0069 16.5 4.5 0.0069 16.5 4.5 2.0 2 0 0 2 2 2 1 bZIP transcription factor HR1 PF02185.16 RLN91547.1 - 0.11 12.6 6.2 0.56 10.4 2.5 2.5 2 0 0 2 2 2 0 Hr1 repeat SWIRM-assoc_2 PF16496.5 RLN91547.1 - 0.17 10.8 9.8 0.21 10.4 9.8 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Macoilin PF09726.9 RLN91547.1 - 0.24 9.9 6.9 0.28 9.7 6.9 1.0 1 0 0 1 1 1 0 Macoilin family Prominin PF05478.11 RLN91547.1 - 0.62 7.9 2.3 0.76 7.7 2.3 1.0 1 0 0 1 1 1 0 Prominin Adaptin_N PF01602.20 RLN91548.1 - 7.8e-40 136.9 0.0 8.7e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 RLN91548.1 - 0.00078 19.5 0.1 0.0024 17.9 0.0 1.7 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 RLN91548.1 - 0.099 12.4 0.3 0.28 10.9 0.0 1.9 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis Ribosomal_L1 PF00687.21 RLN91549.1 - 1.4e-46 158.8 0.2 1.4e-46 158.8 0.2 2.0 2 1 0 2 2 2 1 Ribosomal protein L1p/L10e family Steroid_dh PF02544.16 RLN91550.1 - 4.6e-30 104.6 0.2 7.8e-30 103.8 0.2 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 RLN91550.1 - 0.0002 21.0 0.0 0.00033 20.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family DUF1295 PF06966.12 RLN91550.1 - 0.0013 18.3 0.1 0.0016 18.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Ubiquitin_2 PF14560.6 RLN91550.1 - 0.002 18.5 0.0 0.0087 16.5 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 RLN91550.1 - 0.0026 17.8 0.0 0.032 14.3 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin-like domain PEMT PF04191.13 RLN91550.1 - 0.024 15.0 1.5 0.06 13.7 0.4 2.3 1 1 1 2 2 2 0 Phospholipid methyltransferase GyrI-like PF06445.15 RLN91551.1 - 1.7e-16 60.9 0.0 1.9e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.6 RLN91551.1 - 1.7e-11 44.5 0.0 2.1e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Integron-associated effector binding protein GyrI-like PF06445.15 RLN91552.1 - 1.2e-15 58.1 0.0 1.5e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.6 RLN91552.1 - 2.1e-12 47.5 0.0 2.5e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 Integron-associated effector binding protein Pkinase_Tyr PF07714.17 RLN91553.1 - 1.3e-71 240.9 0.0 2.6e-36 125.3 0.0 4.8 4 1 0 4 4 4 4 Protein tyrosine kinase Pkinase PF00069.25 RLN91553.1 - 1.9e-58 197.9 0.0 2.6e-30 105.7 0.0 5.4 4 2 0 4 4 4 3 Protein kinase domain APH PF01636.23 RLN91553.1 - 0.00048 20.1 13.4 0.0019 18.2 0.0 5.4 5 0 0 5 5 5 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RLN91553.1 - 0.0016 17.8 0.0 0.029 13.7 0.0 2.8 4 0 0 4 4 4 1 Kinase-like Kdo PF06293.14 RLN91553.1 - 0.0062 15.9 0.1 0.58 9.5 0.0 3.2 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3072 PF11272.8 RLN91553.1 - 0.05 13.5 0.5 0.17 11.8 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) DUF3678 PF12435.8 RLN91554.1 - 0.14 11.6 1.1 0.75 9.2 1.1 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Jiraiya PF15038.6 RLN91554.1 - 0.79 9.1 4.1 1.5 8.2 4.1 1.4 1 0 0 1 1 1 0 Jiraiya DUF3995 PF13160.6 RLN91555.1 - 0.03 14.7 0.2 0.051 14.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) 7TM_GPCR_Str PF10326.9 RLN91555.1 - 0.059 12.7 0.1 0.081 12.3 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str Phage_holin_3_6 PF07332.11 RLN91555.1 - 0.44 10.6 2.5 0.87 9.7 2.5 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III PP2C PF00481.21 RLN91556.1 - 9.7e-64 215.5 0.0 1.3e-63 215.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C FHA PF00498.26 RLN91556.1 - 1.9e-16 60.2 0.0 2e-12 47.3 0.0 3.3 3 0 0 3 3 3 2 FHA domain PP2C_2 PF13672.6 RLN91556.1 - 4.9e-07 29.6 0.0 1.7e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C Yop-YscD_cpl PF16697.5 RLN91556.1 - 0.00014 22.2 0.0 0.00054 20.2 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain DUF4663 PF15668.5 RLN91556.1 - 0.13 11.3 2.5 0.2 10.7 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) SpoIIE PF07228.12 RLN91556.1 - 0.13 12.1 1.3 1.6 8.6 0.4 2.5 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) ABC_membrane PF00664.23 RLN91558.1 - 2.3e-54 184.9 7.2 3.2e-54 184.4 7.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN91558.1 - 8.7e-09 36.0 0.0 2.1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 RLN91558.1 - 0.00032 20.4 0.7 0.00079 19.1 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN91558.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 RLN91558.1 - 0.022 15.2 0.0 0.044 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 RLN91558.1 - 0.039 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 RLN91558.1 - 0.057 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 RLN91558.1 - 0.096 12.2 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 RLN91558.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RLN91558.1 - 0.14 12.4 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RLN91558.1 - 0.18 12.4 0.0 0.36 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 RLN91558.1 - 0.23 12.0 0.1 0.47 10.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain Red1 PF07964.11 RLN91559.1 - 0.032 12.5 7.5 0.046 12.0 7.5 1.2 1 0 0 1 1 1 0 Rec10 / Red1 DUF572 PF04502.13 RLN91559.1 - 0.15 11.6 11.2 0.22 11.1 11.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SOG2 PF10428.9 RLN91559.1 - 0.58 9.3 8.2 0.61 9.2 8.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Zip PF02535.22 RLN91559.1 - 2.4 7.3 3.2 3.2 6.9 3.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Abhydrolase_1 PF00561.20 RLN91560.1 - 5.2e-06 26.3 0.1 1.1e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN91560.1 - 0.00025 20.4 0.1 0.0025 17.1 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN91560.1 - 0.0016 19.1 5.5 0.011 16.3 0.3 3.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Glyco_hydro_1 PF00232.18 RLN91561.1 - 1.7e-239 794.8 0.0 2.9e-120 401.8 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 1 Lipase_GDSL_2 PF13472.6 RLN91561.1 - 0.085 13.2 0.0 34 4.8 0.0 3.0 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase family PPAK PF02818.15 RLN91561.1 - 7.2 6.8 8.8 11 6.3 1.2 2.4 2 0 0 2 2 2 0 PPAK motif PPR_2 PF13041.6 RLN91562.1 - 5.4e-13 48.9 0.2 5.9e-06 26.4 0.0 5.0 4 1 1 5 5 5 3 PPR repeat family PPR PF01535.20 RLN91562.1 - 2e-06 27.6 0.2 4.7 7.7 0.0 5.8 6 0 0 6 6 6 2 PPR repeat PPR_long PF17177.4 RLN91562.1 - 3.4e-06 26.6 1.0 0.001 18.5 0.0 3.4 3 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 RLN91562.1 - 6.5e-06 26.1 0.3 0.0039 17.2 0.0 4.1 3 1 1 4 4 4 2 Pentatricopeptide repeat domain Med20 PF08612.11 RLN91562.1 - 0.064 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex WD40_4 PF16300.5 RLN91563.1 - 6.9e-30 102.7 0.1 1.2e-16 60.3 0.0 2.7 2 0 0 2 2 2 2 Type of WD40 repeat WD40 PF00400.32 RLN91563.1 - 1.3e-18 67.0 1.9 0.0026 18.6 0.0 7.2 8 0 0 8 8 8 4 WD domain, G-beta repeat DUF1899 PF08953.11 RLN91563.1 - 1.2e-14 53.9 0.7 3.4e-08 33.2 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF1899) ANAPC4_WD40 PF12894.7 RLN91563.1 - 1.5e-07 31.6 0.0 0.31 11.4 0.0 4.0 3 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN91563.1 - 0.041 12.9 0.0 5.1 6.0 0.0 2.8 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Seryl_tRNA_N PF02403.22 RLN91564.1 - 0.07 13.4 2.8 0.28 11.4 2.8 2.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Cortex-I_coil PF09304.10 RLN91564.1 - 1.3 9.3 9.8 0.88 9.8 6.7 2.4 2 0 0 2 2 2 0 Cortexillin I, coiled coil DEAD PF00270.29 RLN91565.1 - 2.4e-50 170.7 0.0 6e-50 169.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN91565.1 - 3.6e-32 111.0 0.0 3.4e-29 101.4 0.0 2.9 2 1 1 3 3 3 2 Helicase conserved C-terminal domain UTP25 PF06862.12 RLN91565.1 - 0.014 14.2 0.0 0.21 10.3 0.0 2.6 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_11 PF13086.6 RLN91565.1 - 0.099 12.4 6.8 9.2 6.0 6.1 2.7 2 1 0 2 2 2 0 AAA domain AF-4 PF05110.13 RLN91565.1 - 0.12 10.5 15.9 0.16 10.1 15.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CMS1 PF14617.6 RLN91565.1 - 0.17 11.2 0.0 0.17 11.2 0.0 3.7 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Nha1_C PF08619.10 RLN91565.1 - 0.21 10.8 15.3 0.37 9.9 15.3 1.3 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus SOBP PF15279.6 RLN91565.1 - 1.7 9.2 6.1 2.6 8.6 6.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Dsh_C PF12316.8 RLN91565.1 - 7.8 6.8 10.6 14 6.0 10.6 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF218 PF02698.17 RLN91566.1 - 5.3e-12 45.9 0.1 8.4e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 DUF218 domain TPR_2 PF07719.17 RLN91567.1 - 6.7e-30 100.8 12.5 0.014 15.4 0.1 10.0 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.28 RLN91567.1 - 1.7e-26 90.9 13.4 1.7e-06 27.6 0.1 9.1 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 RLN91567.1 - 4e-22 78.3 10.2 0.00055 20.2 0.0 8.0 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 RLN91567.1 - 1.1e-18 65.8 3.7 0.039 14.2 0.0 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 RLN91567.1 - 1.1e-17 64.4 4.3 0.0019 18.8 0.0 6.9 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 RLN91567.1 - 4.5e-15 55.1 12.9 0.085 13.7 0.1 9.1 5 3 5 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 RLN91567.1 - 1.7e-13 50.9 13.9 0.0033 17.9 0.1 5.5 4 1 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 RLN91567.1 - 2.1e-10 40.1 4.7 0.049 13.3 0.0 6.6 5 3 3 8 8 8 2 TPR repeat TPR_6 PF13174.6 RLN91567.1 - 3.6e-09 36.7 8.5 0.17 12.6 0.0 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN91567.1 - 4.7e-09 35.6 12.7 2.1 8.6 0.0 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN91567.1 - 1e-08 35.0 12.7 0.00015 21.9 0.0 7.9 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN91567.1 - 1.6e-07 31.3 6.1 0.048 13.8 0.4 6.1 4 2 3 7 7 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN91567.1 - 0.00016 21.8 13.6 0.5 10.6 0.4 5.0 2 1 4 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 RLN91567.1 - 0.00065 19.0 5.7 0.0029 16.9 2.2 3.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN91567.1 - 0.004 17.0 10.0 0.19 11.7 0.3 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN91567.1 - 0.037 14.1 3.1 29 4.8 0.0 4.5 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.10 RLN91567.1 - 0.071 12.1 0.3 0.39 9.7 0.0 2.1 1 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF4810 PF16068.5 RLN91567.1 - 0.14 12.7 0.0 70 4.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4810) BTAD PF03704.17 RLN91567.1 - 0.72 10.3 4.8 40 4.6 0.0 4.1 5 0 0 5 5 5 0 Bacterial transcriptional activator domain Abhydrolase_1 PF00561.20 RLN91568.1 - 2.1e-15 57.1 0.2 3.4e-15 56.4 0.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 RLN91568.1 - 4e-12 45.5 0.0 1.7e-10 40.3 0.0 2.5 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 RLN91568.1 - 3.8e-05 23.1 0.0 6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 MFS_1 PF07690.16 RLN91569.1 - 4.5e-30 104.8 28.6 4.5e-30 104.8 28.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 RLN91569.1 - 2.2e-28 98.9 20.2 3.6e-21 75.1 0.7 3.2 1 1 2 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 RLN91569.1 - 1.3e-18 67.1 26.3 1.3e-18 67.1 26.3 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3267 PF11667.8 RLN91569.1 - 0.011 16.0 1.4 0.011 16.0 1.4 4.6 4 1 1 5 5 5 0 Putative zincin peptidase WD40 PF00400.32 RLN91570.1 - 1.4e-24 85.8 12.2 5.4e-05 23.9 0.0 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN91570.1 - 3.7e-14 52.8 0.6 8.3e-05 22.8 0.0 4.6 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RLN91570.1 - 6.6e-05 22.9 0.0 0.014 15.3 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 RLN91570.1 - 0.0022 17.0 0.0 0.059 12.3 0.0 2.7 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DEAD PF00270.29 RLN91571.1 - 2.6e-49 167.4 0.0 4.2e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN91571.1 - 4.6e-31 107.4 0.0 1.8e-30 105.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 RLN91571.1 - 8.4e-06 25.2 0.0 1.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 RLN91571.1 - 0.0002 21.4 0.0 0.00035 20.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RLN91571.1 - 0.087 13.1 0.5 0.35 11.2 0.5 2.1 1 1 0 1 1 1 0 AAA domain CDP-OH_P_transf PF01066.21 RLN91572.1 - 5.8e-16 59.0 0.3 5.8e-16 59.0 0.3 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DHHC PF01529.20 RLN91572.1 - 1.5 8.9 7.2 14 5.7 4.5 2.7 2 1 0 2 2 2 0 DHHC palmitoyltransferase DUF4491 PF14898.6 RLN91572.1 - 2.5 8.6 7.7 18 5.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4491) Peptidase_C48 PF02902.19 RLN91573.1 - 0.0015 18.4 0.0 0.003 17.4 0.0 1.4 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain UbiA PF01040.18 RLN91575.1 - 5.1e-52 176.7 17.8 7.6e-52 176.1 17.8 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family DEAD PF00270.29 RLN91576.1 - 1.5e-22 80.2 0.0 4.8e-22 78.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN91576.1 - 1.8e-12 47.6 0.0 8.4e-12 45.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN91576.1 - 0.00058 19.9 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 RLN91579.1 - 1.2e-07 32.3 0.0 3.4e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain SH2 PF00017.24 RLN91579.1 - 2e-05 24.6 0.0 3.9e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 SH2 domain NACHT PF05729.12 RLN91579.1 - 0.00031 20.7 0.2 0.0016 18.4 0.1 2.2 2 1 0 2 2 2 1 NACHT domain dNK PF01712.19 RLN91579.1 - 0.055 13.3 0.0 0.12 12.3 0.0 1.5 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_22 PF13401.6 RLN91579.1 - 0.078 13.3 0.0 0.25 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 RLN91579.1 - 0.15 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Methyltr_RsmB-F PF01189.17 RLN91580.1 - 5.9e-37 127.3 0.0 1.1e-34 119.9 0.0 2.2 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 RLN91580.1 - 0.019 15.1 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase MFMR PF07777.11 RLN91580.1 - 0.065 13.7 0.1 0.13 12.8 0.1 1.4 1 0 0 1 1 1 0 G-box binding protein MFMR Methyltransf_24 PF13578.6 RLN91580.1 - 0.12 13.4 0.0 0.91 10.6 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Voltage_CLC PF00654.20 RLN91582.1 - 6.7e-75 252.5 33.2 1.2e-74 251.8 33.2 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 RLN91582.1 - 0.00045 20.6 0.1 0.73 10.3 0.0 2.5 2 0 0 2 2 2 2 CBS domain DUF4149 PF13664.6 RLN91583.1 - 0.00062 20.0 4.0 0.00062 20.0 4.0 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4149) Pkinase PF00069.25 RLN91584.1 - 4.2e-38 131.2 0.0 5.1e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN91584.1 - 2.2e-34 118.9 0.0 2.8e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN91584.1 - 0.0081 15.0 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 RLN91584.1 - 0.097 12.0 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IQ PF00612.27 RLN91588.1 - 4.3e-26 88.2 196.1 7.2e-05 22.2 2.2 24.6 24 1 1 25 25 25 17 IQ calmodulin-binding motif WW PF00397.26 RLN91588.1 - 7.1e-16 58.0 13.3 4.2e-09 36.3 1.6 2.6 2 0 0 2 2 2 2 WW domain GCK PF07802.11 RLN91589.1 - 7.4e-17 61.5 3.5 1.5e-16 60.5 3.5 1.5 1 0 0 1 1 1 1 GCK domain CX9C PF16860.5 RLN91589.1 - 0.11 12.5 0.1 0.43 10.6 0.1 1.9 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, MinC_C PF03775.16 RLN91590.1 - 2.4e-29 101.3 0.9 3.8e-29 100.7 0.1 1.7 2 0 0 2 2 2 1 Septum formation inhibitor MinC, C-terminal domain FapA PF03961.13 RLN91590.1 - 0.034 12.7 0.2 0.034 12.7 0.2 1.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A Dicty_REP PF05086.12 RLN91590.1 - 0.44 8.5 1.7 0.47 8.4 1.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein COPIIcoated_ERV PF07970.12 RLN91591.1 - 1.1e-32 113.6 0.1 2.3e-32 112.7 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 RLN91591.1 - 2.3e-21 75.9 0.2 4.9e-21 74.9 0.2 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.20 RLN91591.1 - 2.4e-21 75.7 0.1 4.7e-21 74.7 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 RLN91591.1 - 0.003 18.0 0.1 0.0077 16.7 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RLN91591.1 - 0.04 14.2 1.7 0.31 11.4 0.0 2.7 3 0 0 3 3 3 0 Thioredoxin-like DZR PF12773.7 RLN91592.1 - 3.8e-13 49.2 9.8 5.9e-07 29.4 4.6 2.3 2 0 0 2 2 2 2 Double zinc ribbon zinc_ribbon_2 PF13240.6 RLN91592.1 - 8.7e-07 28.5 21.6 0.0028 17.3 1.2 3.3 3 0 0 3 3 3 3 zinc-ribbon domain zinc_ribbon_15 PF17032.5 RLN91592.1 - 4.9e-05 24.0 13.1 0.014 16.1 0.3 3.1 2 1 1 3 3 3 2 zinc-ribbon family UPF0547 PF10571.9 RLN91592.1 - 7.9e-05 22.6 23.0 0.0007 19.6 7.8 3.5 3 0 0 3 3 3 2 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.6 RLN91592.1 - 0.015 14.7 1.3 0.015 14.7 1.3 3.6 3 1 0 3 3 3 0 zinc-ribbon domain zf-AD PF07776.15 RLN91592.1 - 0.072 13.3 0.4 0.072 13.3 0.4 2.5 2 1 0 2 2 2 0 Zinc-finger associated domain (zf-AD) zinc-ribbon_6 PF10005.9 RLN91592.1 - 0.29 11.8 13.0 6.6 7.5 4.9 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.6 RLN91592.1 - 0.33 10.9 0.2 0.33 10.9 0.2 4.5 5 0 0 5 5 5 0 Nudix N-terminal Cytochrom_c3_2 PF14537.6 RLN91592.1 - 3.5 8.1 13.3 0.93 10.0 0.4 2.9 3 1 0 3 3 3 0 Cytochrome c3 NOB1_Zn_bind PF08772.11 RLN91592.1 - 7.4 6.8 18.8 5.8 7.1 2.7 3.4 2 1 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zf-B_box PF00643.24 RLN91592.1 - 9.6 6.5 15.0 2 8.7 0.9 3.2 3 0 0 3 3 3 0 B-box zinc finger zf-RING_2 PF13639.6 RLN91594.1 - 2.6e-08 34.0 12.1 2.6e-08 34.0 12.1 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 RLN91594.1 - 9.4e-06 25.8 9.4 2.5e-05 24.5 9.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 RLN91594.1 - 7.9e-05 22.4 10.4 0.00022 21.0 10.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN91594.1 - 0.00011 21.9 11.9 0.00023 21.0 11.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN91594.1 - 0.00015 21.7 8.5 0.00039 20.4 8.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN91594.1 - 0.00078 19.3 11.7 0.0016 18.3 11.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RLN91594.1 - 0.002 17.9 11.2 0.0045 16.8 11.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RLN91594.1 - 0.013 15.7 0.4 0.013 15.7 0.4 2.1 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RLN91594.1 - 0.025 14.4 8.9 0.057 13.3 8.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 RLN91594.1 - 0.038 13.7 7.4 0.081 12.7 7.4 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 RLN91594.1 - 0.073 13.1 5.3 0.19 11.8 5.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 RLN91594.1 - 0.88 9.2 8.1 3.8 7.2 8.3 2.0 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-UDP PF14569.6 RLN91594.1 - 1.6 8.9 8.1 0.39 10.9 4.3 2.0 2 0 0 2 2 2 0 Zinc-binding RING-finger RCC1 PF00415.18 RLN91595.1 - 7.9e-82 269.7 21.5 4.1e-15 56.1 0.1 8.2 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN91595.1 - 1.8e-18 65.8 48.0 8.6e-08 31.8 2.4 7.9 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Surp PF01805.20 RLN91596.1 - 7.7e-16 57.8 0.0 1.1e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Surp module PX PF00787.24 RLN91598.1 - 2.6e-19 69.3 0.0 2.9e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 PX domain DUF5078 PF16877.5 RLN91598.1 - 0.058 13.9 0.5 3.3 8.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5078) SpoVR PF04293.13 RLN91598.1 - 0.12 11.0 0.4 7.8 5.1 0.0 2.1 2 0 0 2 2 2 0 SpoVR like protein PX PF00787.24 RLN91599.1 - 1.7e-10 40.9 0.0 2.5e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 PX domain PX PF00787.24 RLN91600.1 - 1.4e-10 41.2 0.0 2.4e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 PX domain HTH_9 PF08221.11 RLN91601.1 - 0.00017 21.6 0.4 0.0014 18.7 0.4 2.2 1 1 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain DNA_pol3_alpha PF07733.12 RLN91601.1 - 0.0012 18.5 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain PBP1_TM PF14812.6 RLN91602.1 - 0.072 13.5 0.2 0.072 13.5 0.2 2.6 3 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RR_TM4-6 PF06459.12 RLN91602.1 - 0.46 10.3 4.2 0.22 11.3 1.2 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4577 PF15145.6 RLN91603.1 - 0.006 16.6 0.0 0.0064 16.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4577) Gemini_mov PF01708.16 RLN91603.1 - 0.026 14.3 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Geminivirus putative movement protein Peptidase_M14 PF00246.24 RLN91604.1 - 0.00015 21.7 0.0 0.00035 20.5 0.0 1.7 1 1 0 1 1 1 1 Zinc carboxypeptidase Oest_recep PF02159.15 RLN91604.1 - 0.077 13.5 0.5 0.19 12.2 0.5 1.7 1 0 0 1 1 1 0 Oestrogen receptor Macoilin PF09726.9 RLN91604.1 - 9.8 4.6 8.2 13 4.2 8.2 1.1 1 0 0 1 1 1 0 Macoilin family Pepdidase_M14_N PF18027.1 RLN91605.1 - 4.8e-11 43.0 0.0 8.9e-11 42.1 0.0 1.4 1 1 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AAA PF00004.29 RLN91606.1 - 1e-14 55.1 0.0 5.5e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN91606.1 - 0.00022 21.6 3.9 0.0019 18.6 0.0 3.3 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 RLN91606.1 - 0.025 14.8 0.0 0.13 12.5 0.0 2.3 1 0 0 1 1 1 0 AAA domain CobW_C PF07683.14 RLN91606.1 - 0.031 14.2 0.3 0.12 12.4 0.1 2.1 2 0 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain ATPase_2 PF01637.18 RLN91606.1 - 0.034 14.1 0.0 0.94 9.3 0.0 2.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 RLN91606.1 - 0.047 13.7 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 RLN91606.1 - 0.088 13.2 0.0 1.4 9.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 RLN91606.1 - 0.094 12.1 0.1 0.23 10.8 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 RLN91606.1 - 0.1 12.3 0.0 0.35 10.6 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RLN91606.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 RLN91606.1 - 0.12 12.5 2.1 0.15 12.2 0.0 2.3 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 RLN91606.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 RLN91606.1 - 0.4 10.2 2.8 0.67 9.5 0.1 2.6 2 1 1 3 3 3 0 AAA domain Catalase PF00199.19 RLN91607.1 - 1.4e-116 389.8 0.2 8.9e-114 380.5 0.2 2.0 1 1 0 1 1 1 1 Catalase DUF2244 PF10003.9 RLN91609.1 - 7 6.3 8.8 4.8 6.9 3.8 2.7 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Ion_trans PF00520.31 RLN91610.1 - 4.5e-16 58.8 17.2 9.7e-12 44.6 5.6 2.8 3 0 0 3 3 3 2 Ion transport protein Ion_trans_2 PF07885.16 RLN91610.1 - 4.1e-08 33.1 20.0 1.1e-05 25.3 5.0 3.4 3 0 0 3 3 3 2 Ion channel cNMP_binding PF00027.29 RLN91610.1 - 2.4e-07 30.7 0.0 7.1e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF3082 PF11282.8 RLN91610.1 - 0.019 15.2 4.5 0.85 9.9 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3082) COX6C PF02937.15 RLN91610.1 - 0.16 12.1 2.2 0.6 10.3 0.5 2.8 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIc LRR_8 PF13855.6 RLN91611.1 - 1.4e-17 63.1 17.6 1.9e-10 40.3 2.9 4.5 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 RLN91611.1 - 1.2e-15 57.3 18.4 0.0005 20.4 0.4 5.7 2 2 2 5 5 5 5 Leucine Rich repeats (2 copies) Catalase-rel PF06628.12 RLN91611.1 - 3.7e-13 49.5 0.1 1.3e-12 47.8 0.1 2.0 1 0 0 1 1 1 1 Catalase-related immune-responsive TFIIA PF03153.13 RLN91611.1 - 0.0027 17.8 12.5 0.0027 17.8 12.5 2.0 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DASH_Dam1 PF08653.10 RLN91611.1 - 0.054 13.3 0.7 74 3.3 0.0 4.2 3 0 0 3 3 3 0 DASH complex subunit Dam1 WW PF00397.26 RLN91611.1 - 0.25 11.4 1.9 0.56 10.3 1.9 1.6 1 0 0 1 1 1 0 WW domain LRR_1 PF00560.33 RLN91611.1 - 0.4 11.4 14.7 29 5.7 0.1 7.0 8 0 0 8 8 7 0 Leucine Rich Repeat DNA_pol_phi PF04931.13 RLN91611.1 - 1 7.4 24.6 1.9 6.5 24.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 RLN91611.1 - 1.6 8.0 25.0 3.3 7.0 25.0 1.5 1 0 0 1 1 1 0 BUD22 LRR_6 PF13516.6 RLN91611.1 - 6 7.2 12.0 7.3 6.9 0.2 4.2 4 0 0 4 4 4 0 Leucine Rich repeat DUF4746 PF15928.5 RLN91611.1 - 6 6.2 12.1 17 4.7 12.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MMR_HSR1 PF01926.23 RLN91612.1 - 9.3e-19 67.6 0.0 1.5e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RLN91612.1 - 1.7e-05 24.8 0.2 0.0013 18.7 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 RLN91612.1 - 2e-05 24.1 0.1 4.1e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 RLN91612.1 - 2.1e-05 24.6 0.6 0.00049 20.2 0.2 2.3 1 1 0 2 2 2 1 Dynamin family Septin PF00735.18 RLN91612.1 - 0.00012 21.5 0.0 0.01 15.2 0.0 2.2 1 1 0 1 1 1 1 Septin GTP_EFTU PF00009.27 RLN91612.1 - 0.0034 16.9 0.1 0.73 9.3 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 RLN91612.1 - 0.032 13.6 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 RLN91612.1 - 0.037 14.5 0.0 0.069 13.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Dimerisation PF08100.11 RLN91612.1 - 0.082 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain AAA_29 PF13555.6 RLN91612.1 - 0.099 12.4 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.16 RLN91612.1 - 0.12 11.7 0.1 0.38 10.0 0.0 1.7 2 0 0 2 2 2 0 AIG1 family IIGP PF05049.13 RLN91612.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) TMEM89 PF15098.6 RLN91614.1 - 0.0036 17.5 1.0 0.0076 16.4 0.0 2.0 2 0 0 2 2 2 1 TMEM89 protein family LRR_8 PF13855.6 RLN91615.1 - 2.3e-45 152.2 34.3 2.9e-08 33.3 3.6 8.8 6 1 4 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 RLN91615.1 - 2.5e-37 126.3 28.0 3.6e-05 24.0 0.3 11.6 5 4 7 13 13 13 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN91615.1 - 3.3e-07 29.9 29.6 7.9 7.5 0.1 13.2 15 0 0 15 15 15 1 Leucine Rich Repeat LRR_6 PF13516.6 RLN91615.1 - 3.4e-07 29.8 26.6 0.2 11.8 0.1 12.3 15 0 0 15 15 15 2 Leucine Rich repeat LRR_9 PF14580.6 RLN91615.1 - 2.9e-05 23.7 13.1 4.4 6.8 0.3 5.7 3 2 2 5 5 5 4 Leucine-rich repeat HAUS-augmin3 PF14932.6 RLN91615.1 - 2 7.9 11.6 6.2 6.3 11.6 1.8 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4763 PF15960.5 RLN91615.1 - 2.6 7.3 9.2 3.7 6.8 3.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Pkinase PF00069.25 RLN91616.1 - 1.7e-55 188.2 0.0 2.5e-55 187.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN91616.1 - 5.4e-37 127.5 0.0 8e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN91616.1 - 1.2e-07 31.3 0.0 2.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RLN91616.1 - 2.1e-06 26.8 0.0 3.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 RLN91616.1 - 0.051 12.9 0.8 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 RLN91616.1 - 0.16 11.0 0.1 0.24 10.4 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Cyclin PF08613.11 RLN91617.1 - 2.4e-15 57.3 0.0 2.4e-15 57.3 0.0 3.0 2 1 0 2 2 2 1 Cyclin WW PF00397.26 RLN91617.1 - 1.2e-08 34.9 2.0 1.2e-08 34.9 2.0 1.9 2 0 0 2 2 2 1 WW domain Cyclin_N PF00134.23 RLN91617.1 - 7.5e-07 28.9 0.1 1.4e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Glyco_hydro_12 PF01670.16 RLN91618.1 - 1.9e-43 149.0 8.7 1.9e-43 149.0 8.7 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 12 FAD_binding_1 PF00667.20 RLN91619.1 - 5.1e-50 170.1 0.0 9e-50 169.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 RLN91619.1 - 9.7e-29 100.4 0.0 2.4e-28 99.1 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 RLN91619.1 - 2.5e-13 50.6 0.0 4.9e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain AMP-binding PF00501.28 RLN91619.1 - 0.033 12.8 0.0 0.051 12.2 0.0 1.2 1 0 0 1 1 1 0 AMP-binding enzyme Atx10homo_assoc PF09759.9 RLN91620.1 - 6.5e-33 112.7 0.2 8.1e-31 106.0 0.0 2.9 2 1 0 2 2 2 2 Spinocerebellar ataxia type 10 protein domain Haem_bd PF14376.6 RLN91620.1 - 0.036 14.0 0.2 0.081 12.9 0.2 1.5 1 0 0 1 1 1 0 Haem-binding domain SKN1 PF03935.15 RLN91621.1 - 8.6e-62 209.2 14.2 2.3e-40 138.5 9.0 4.8 2 2 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) NCA2 PF08637.10 RLN91622.1 - 1.3e-08 34.4 0.0 5.8e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 CLZ PF16526.5 RLN91622.1 - 0.096 13.1 0.3 0.33 11.3 0.1 2.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Rhamno_transf PF11316.8 RLN91624.1 - 0.00042 19.8 0.2 0.49 9.7 0.1 2.5 2 0 0 2 2 2 2 Putative rhamnosyl transferase STIL_N PF15253.6 RLN91624.1 - 0.0073 15.3 0.0 0.96 8.3 0.0 2.2 2 0 0 2 2 2 2 SCL-interrupting locus protein N-terminus Cep57_MT_bd PF06657.13 RLN91624.1 - 0.016 15.6 1.5 6.3 7.3 0.1 3.5 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Chitin_synth_1 PF01644.17 RLN91624.1 - 0.027 14.4 0.1 5.7 6.9 0.0 2.5 2 0 0 2 2 2 0 Chitin synthase CK2S PF15011.6 RLN91624.1 - 0.073 13.0 5.4 1.5 8.7 0.3 3.2 2 2 0 2 2 2 0 Casein Kinase 2 substrate Muted PF14942.6 RLN91624.1 - 3.8 7.9 8.5 12 6.3 1.1 2.7 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Enkurin PF13864.6 RLN91624.1 - 8 7.0 15.4 3.2 8.3 1.7 3.5 3 1 1 4 4 4 0 Calmodulin-binding Ank_2 PF12796.7 RLN91625.1 - 8.4e-25 87.2 7.3 1.1e-13 51.6 0.3 4.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN91625.1 - 1.2e-15 57.3 8.3 0.0016 18.7 0.4 6.2 3 3 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN91625.1 - 2e-11 44.2 10.4 2.4e-05 24.8 0.2 5.5 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN91625.1 - 2.2e-11 42.9 14.0 0.0022 18.3 0.2 7.1 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 RLN91625.1 - 1.6e-08 34.6 18.4 0.00094 19.5 0.1 6.8 7 0 0 7 7 7 2 Ankyrin repeat HECT PF00632.25 RLN91625.1 - 8.5e-07 28.8 0.0 2.3e-05 24.0 0.0 2.5 2 1 0 2 2 2 1 HECT-domain (ubiquitin-transferase) PHD PF00628.29 RLN91625.1 - 5.4e-06 26.2 5.0 5.4e-06 26.2 5.0 2.7 2 0 0 2 2 2 1 PHD-finger CDC27 PF09507.10 RLN91625.1 - 0.35 10.2 14.5 0.53 9.6 14.5 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Glyco_hydro_72 PF03198.14 RLN91626.1 - 0.00055 19.3 0.1 0.00078 18.8 0.1 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Pkinase PF00069.25 RLN91627.1 - 1.3e-48 165.7 0.0 1.7e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN91627.1 - 9.7e-45 152.9 0.0 1.3e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN91627.1 - 0.0055 16.1 0.0 0.008 15.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN91627.1 - 0.0057 16.6 0.0 0.1 12.5 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RabGAP-TBC PF00566.18 RLN91628.1 - 2.6e-10 40.4 0.4 8.2e-10 38.7 0.1 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Myotub-related PF06602.14 RLN91629.1 - 1.2e-66 225.1 0.0 1.3e-66 225.0 0.0 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 RLN91629.1 - 0.00041 20.4 0.0 0.00056 19.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 RLN91629.1 - 0.0058 16.5 0.0 0.0091 15.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RLN91629.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Myotub-related PF06602.14 RLN91630.1 - 7e-36 123.9 0.0 1.1e-35 123.2 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain BBL5 PF07289.11 RLN91630.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein Peptidase_C1 PF00112.23 RLN91631.1 - 2.3e-54 184.8 13.0 2.3e-54 184.8 13.0 2.3 2 1 0 2 2 2 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RLN91631.1 - 0.0013 17.6 1.5 0.025 13.4 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family SOG2 PF10428.9 RLN91631.1 - 3.2 6.8 24.9 5 6.2 24.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein FAA_hydrolase PF01557.18 RLN91632.1 - 3.3e-62 210.0 0.0 4.6e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 RLN91632.1 - 0.0036 18.2 0.1 0.0071 17.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2437) DUF572 PF04502.13 RLN91633.1 - 0.013 15.2 1.0 0.023 14.3 1.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3287 PF11690.8 RLN91635.1 - 0.078 12.7 0.9 0.75 9.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Auxin_repressed PF05564.12 RLN91636.1 - 0.049 14.3 0.3 0.053 14.2 0.3 1.1 1 0 0 1 1 1 0 Dormancy/auxin associated protein Spt4 PF06093.13 RLN91637.1 - 4.2e-28 97.2 1.5 5.1e-28 97.0 1.5 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger HIPIP PF01355.17 RLN91637.1 - 0.13 12.6 4.7 0.2 12.0 1.7 2.1 1 1 1 2 2 2 0 High potential iron-sulfur protein SH3_3 PF08239.11 RLN91638.1 - 1.2e-05 25.4 0.0 0.023 15.0 0.0 2.6 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_4 PF06347.13 RLN91638.1 - 0.0004 20.2 0.0 0.031 14.1 0.0 3.2 3 0 0 3 3 3 1 Bacterial SH3 domain Myosin_TH1 PF06017.13 RLN91639.1 - 8.7e-05 22.3 0.2 0.034 13.8 0.0 2.9 1 1 2 3 3 3 3 Unconventional myosin tail, actin- and lipid-binding Self-incomp_S1 PF05938.11 RLN91639.1 - 0.16 12.5 0.0 0.55 10.8 0.0 1.9 1 1 0 1 1 1 0 Plant self-incompatibility protein S1 Stm1_N PF09598.10 RLN91640.1 - 0.079 13.8 1.6 0.19 12.6 1.5 1.6 1 1 0 1 1 1 0 Stm1 Peptidase_S10 PF00450.22 RLN91641.1 - 1.1e-79 268.8 0.0 1.6e-79 268.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase MAP70 PF07058.11 RLN91641.1 - 0.03 13.1 0.0 0.044 12.5 0.0 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 Dynein_light PF01221.18 RLN91642.1 - 8.4e-23 80.5 0.9 9.9e-23 80.3 0.9 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 WD40 PF00400.32 RLN91643.1 - 1.7e-66 218.6 15.8 1.4e-09 38.4 0.0 8.6 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN91643.1 - 1.3e-24 86.3 1.7 0.00043 20.5 0.0 6.3 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 RLN91643.1 - 1.3e-09 38.4 0.0 2.7e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.11 RLN91643.1 - 2.6e-09 37.2 0.2 0.00076 19.4 0.0 3.7 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 RLN91643.1 - 4.1e-09 35.8 0.1 0.1 11.5 0.0 5.0 3 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RLN91643.1 - 7.3e-06 24.9 1.4 1.3 7.6 0.0 4.3 2 2 1 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.12 RLN91643.1 - 1e-05 25.3 5.0 2.1 8.4 0.0 4.8 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat IKI3 PF04762.12 RLN91643.1 - 0.00021 19.5 0.7 0.043 11.8 0.1 2.5 2 1 0 3 3 3 2 IKI3 family Nbas_N PF15492.6 RLN91643.1 - 0.00026 20.4 0.4 1.4 8.2 0.0 4.0 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 RLN91643.1 - 0.00087 18.1 0.1 0.51 9.0 0.0 2.3 2 0 0 2 2 2 2 Nup133 N terminal like WD40_like PF17005.5 RLN91643.1 - 0.018 14.4 0.0 13 5.0 0.0 3.6 4 0 0 4 4 4 0 WD40-like domain Cytochrom_D1 PF02239.16 RLN91643.1 - 0.022 13.3 0.1 0.33 9.4 0.0 2.5 2 1 1 3 3 3 0 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 RLN91643.1 - 0.073 12.1 0.1 0.24 10.4 0.0 1.9 2 0 0 2 2 2 0 Coatomer WD associated region HPS3_N PF14761.6 RLN91643.1 - 0.11 12.0 0.0 0.31 10.5 0.0 1.8 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 CHAP PF05257.16 RLN91643.1 - 0.19 12.3 2.8 13 6.5 0.1 2.8 2 1 0 2 2 2 0 CHAP domain Proteasome_A_N PF10584.9 RLN91643.1 - 0.38 10.5 5.5 34 4.3 0.2 3.8 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature FYVE PF01363.21 RLN91645.1 - 9.9e-10 38.4 7.7 2.4e-09 37.2 7.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 RLN91645.1 - 1.1e-06 29.3 0.1 4.8e-06 27.2 0.1 2.1 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 RLN91645.1 - 0.023 15.0 0.1 0.052 13.9 0.1 1.6 1 0 0 1 1 1 0 GAF domain zf-RING_5 PF14634.6 RLN91645.1 - 0.16 11.9 8.0 0.38 10.8 8.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 RLN91645.1 - 0.7 10.3 7.7 2.1 8.7 7.7 1.9 1 0 0 1 1 1 0 Ring finger domain BT1 PF03092.16 RLN91646.1 - 2.5e-13 49.1 3.0 4.4e-11 41.7 0.5 2.4 2 0 0 2 2 2 2 BT1 family PUCC PF03209.15 RLN91646.1 - 0.006 15.6 0.2 0.006 15.6 0.2 2.5 2 1 0 2 2 2 1 PUCC protein A_deamin PF02137.18 RLN91647.1 - 8.6e-62 209.5 0.5 6.4e-59 200.0 0.5 2.1 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain CH_2 PF06294.11 RLN91649.1 - 9.4e-22 77.0 0.0 2.1e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 RLN91649.1 - 8.3e-05 22.3 0.0 0.00031 20.5 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain DUF3349 PF11829.8 RLN91650.1 - 0.19 12.5 0.8 23 5.8 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) DUF1488 PF07369.11 RLN91650.1 - 0.38 10.8 2.0 1 9.4 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1488) NTP_transf_2 PF01909.23 RLN91651.1 - 0.03 14.6 0.0 0.053 13.8 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain Pectate_lyase PF03211.13 RLN91652.1 - 4.7e-36 124.2 8.7 4.7e-36 124.2 8.7 2.0 2 0 0 2 2 2 1 Pectate lyase Zip PF02535.22 RLN91652.1 - 0.78 8.9 7.9 2.2 7.4 7.9 1.8 1 0 0 1 1 1 0 ZIP Zinc transporter AMP-binding PF00501.28 RLN91653.1 - 1.9e-78 263.9 0.0 2.9e-78 263.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 RLN91653.1 - 2.2e-65 220.4 0.0 3.1e-65 219.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Thioesterase PF00975.20 RLN91653.1 - 1.4e-20 74.4 0.1 2.9e-20 73.4 0.1 1.5 1 0 0 1 1 1 1 Thioesterase domain Epimerase PF01370.21 RLN91653.1 - 9.1e-14 51.5 0.0 2.1e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 RLN91653.1 - 1.8e-11 44.2 0.5 6.3e-11 42.5 0.1 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 RLN91653.1 - 1.9e-10 41.6 0.0 6.7e-10 39.8 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 RLN91653.1 - 9.5e-08 31.4 0.0 4.9e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Abhydrolase_6 PF12697.7 RLN91653.1 - 1.1e-06 29.4 7.8 3.8e-06 27.7 7.8 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family GDP_Man_Dehyd PF16363.5 RLN91653.1 - 1e-05 25.2 0.0 8.1e-05 22.2 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 RLN91653.1 - 0.0028 16.8 0.1 7 5.6 0.0 3.2 3 0 0 3 3 3 2 RmlD substrate binding domain NmrA PF05368.13 RLN91653.1 - 0.026 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Lipase_3 PF01764.25 RLN91653.1 - 0.056 13.3 0.5 0.41 10.5 0.2 2.3 2 0 0 2 2 2 0 Lipase (class 3) DUF4242 PF14026.6 RLN91653.1 - 0.067 13.4 0.0 0.38 11.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4242) Polysacc_synt_2 PF02719.15 RLN91653.1 - 0.081 12.0 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Abhydrolase_1 PF00561.20 RLN91653.1 - 0.13 11.9 0.3 10 5.7 0.2 2.4 1 1 1 2 2 2 0 alpha/beta hydrolase fold Sugar_tr PF00083.24 RLN91654.1 - 4.9e-23 81.7 10.3 5.3e-23 81.6 10.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Dicty_REP PF05086.12 RLN91655.1 - 0.39 8.6 2.6 0.64 7.9 2.6 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf_CCCH_4 PF18345.1 RLN91657.1 - 3.2e-19 68.3 58.1 1.4e-05 25.0 4.0 6.6 6 0 0 6 6 6 5 Zinc finger domain zf-CCCH PF00642.24 RLN91657.1 - 3.3e-19 68.3 48.4 1.3e-05 24.9 1.9 6.4 6 0 0 6 6 6 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 RLN91657.1 - 1.4e-18 66.2 48.1 1.3e-07 31.2 2.1 6.6 6 0 0 6 6 6 5 CCCH-type zinc finger Torus PF16131.5 RLN91657.1 - 7.7e-17 62.0 25.0 0.00069 20.3 0.2 5.4 3 1 2 5 5 5 4 Torus domain zf-RING_2 PF13639.6 RLN91657.1 - 3.5e-09 36.8 8.9 1.1e-07 32.1 4.5 4.0 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 RLN91657.1 - 2.2e-06 27.4 3.4 2.2e-06 27.4 3.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.6 RLN91657.1 - 4.4e-06 26.9 51.2 0.018 15.5 2.9 6.4 6 0 0 6 6 6 4 RNA-binding, Nab2-type zinc finger zf-RING_5 PF14634.6 RLN91657.1 - 1.5e-05 24.8 4.0 1.5e-05 24.8 4.0 3.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RLN91657.1 - 6.4e-05 22.9 3.5 0.00078 19.4 3.2 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RLN91657.1 - 9.3e-05 22.2 3.0 9.3e-05 22.2 3.0 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_3 PF15663.5 RLN91657.1 - 0.00012 22.3 26.5 0.04 14.1 1.1 4.8 4 1 1 5 5 5 4 Zinc-finger containing family zf-RING_11 PF17123.5 RLN91657.1 - 0.0025 17.5 3.7 0.11 12.2 2.4 3.1 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 RLN91657.1 - 0.0066 16.3 3.0 0.0066 16.3 3.0 2.9 3 1 0 3 3 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 RLN91657.1 - 0.023 15.0 8.1 0.42 10.9 7.9 3.1 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 RLN91657.1 - 0.28 11.1 8.6 0.96 9.3 6.7 3.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 RLN91657.1 - 0.48 10.6 7.1 0.13 12.4 3.2 2.2 2 0 0 2 2 1 0 FANCL C-terminal domain FOLN PF09289.10 RLN91657.1 - 0.65 10.2 5.3 6 7.1 0.4 2.9 2 0 0 2 2 2 0 Follistatin/Osteonectin-like EGF domain zf-C3HC4_4 PF15227.6 RLN91657.1 - 3.3 7.9 10.2 0.13 12.4 2.4 2.8 3 0 0 3 3 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 RLN91657.1 - 6.1 7.0 11.1 0.22 11.6 2.8 2.9 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger bZIP_2 PF07716.15 RLN91658.1 - 0.24 11.5 17.3 0.055 13.6 6.6 2.5 2 0 0 2 2 2 0 Basic region leucine zipper TMEM192 PF14802.6 RLN91658.1 - 0.3 10.2 0.6 0.48 9.5 0.6 1.3 1 0 0 1 1 1 0 TMEM192 family bZIP_1 PF00170.21 RLN91658.1 - 3.6 7.8 17.3 0.44 10.7 10.3 2.2 1 1 1 2 2 2 0 bZIP transcription factor TMEM65 PF10507.9 RLN91659.1 - 1.1e-44 150.9 3.8 1.1e-44 150.9 3.8 1.7 2 0 0 2 2 2 1 Transmembrane protein 65 Rib_5-P_isom_A PF06026.14 RLN91660.1 - 2.4e-62 209.6 0.0 3.2e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind PF04198.13 RLN91660.1 - 0.0088 15.2 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative sugar-binding domain DeoRC PF00455.22 RLN91660.1 - 0.033 14.1 0.1 0.098 12.6 0.0 1.7 2 0 0 2 2 2 0 DeoR C terminal sensor domain Ank_4 PF13637.6 RLN91662.1 - 0.042 14.4 0.0 0.33 11.6 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) SRP54 PF00448.22 RLN91663.1 - 1.9e-51 174.5 0.0 3.8e-51 173.5 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 RLN91663.1 - 3.9e-43 148.4 12.8 5.4e-43 148.0 12.8 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal MeaB PF03308.16 RLN91663.1 - 4.3e-08 32.5 0.0 1.1e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 RLN91663.1 - 6.2e-05 23.4 0.0 0.0003 21.2 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 RLN91663.1 - 0.00071 19.3 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 RLN91663.1 - 0.00073 19.5 0.7 0.01 15.8 0.1 2.5 3 0 0 3 3 3 1 NTPase CbiA PF01656.23 RLN91663.1 - 0.0012 18.9 0.0 0.0056 16.7 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 RLN91663.1 - 0.0017 18.5 0.5 0.01 15.9 0.1 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase ETF PF01012.21 RLN91663.1 - 0.0028 17.5 0.3 0.08 12.8 0.0 2.6 2 1 1 3 3 3 1 Electron transfer flavoprotein domain AAA_24 PF13479.6 RLN91663.1 - 0.011 15.4 0.1 0.14 11.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain DAP3 PF10236.9 RLN91663.1 - 0.04 13.1 0.0 0.065 12.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Fer4_NifH PF00142.18 RLN91663.1 - 0.046 13.2 0.1 0.091 12.2 0.1 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RsgA_GTPase PF03193.16 RLN91663.1 - 0.078 12.9 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 RLN91663.1 - 0.12 12.8 0.0 0.37 11.2 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN91663.1 - 0.15 12.3 0.2 0.56 10.5 0.1 2.1 2 1 0 2 2 2 0 AAA domain A_deaminase PF00962.22 RLN91664.1 - 5e-23 81.9 0.3 1.1e-16 61.1 0.1 2.3 2 1 0 2 2 2 2 Adenosine/AMP deaminase DUF805 PF05656.14 RLN91666.1 - 0.13 12.7 0.2 0.16 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Elicitin PF00964.17 RLN91667.1 - 6.9e-05 22.9 5.5 0.0002 21.4 5.5 1.8 1 0 0 1 1 1 1 Elicitin Pkinase PF00069.25 RLN91668.1 - 7.8e-22 77.9 0.0 1.9e-17 63.5 0.0 2.5 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN91668.1 - 1.8e-09 37.2 0.0 9.4e-09 34.9 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 RLN91668.1 - 0.00018 20.9 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN91668.1 - 0.00026 21.0 0.1 0.0039 17.1 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN91668.1 - 0.18 10.5 0.0 0.36 9.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Aminotran_1_2 PF00155.21 RLN91669.1 - 5.1e-53 180.5 0.0 6.8e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 RLN91669.1 - 0.006 15.2 0.0 0.0097 14.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.13 RLN91669.1 - 0.083 11.8 0.0 0.21 10.4 0.0 1.4 1 1 0 1 1 1 0 Allinase DUF1084 PF06454.11 RLN91670.1 - 2.9e-08 33.4 1.6 3.7e-08 33.1 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) TrmO PF01980.16 RLN91671.1 - 2.6e-23 82.5 0.1 7.2e-23 81.1 0.1 1.8 1 1 0 1 1 1 1 tRNA-methyltransferase O TrmO_C PF18389.1 RLN91671.1 - 0.096 12.8 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 TrmO C-terminal domain BUD22 PF09073.10 RLN91672.1 - 2 7.6 8.8 2.5 7.4 8.8 1.2 1 0 0 1 1 1 0 BUD22 SPX PF03105.19 RLN91672.1 - 2.2 8.1 9.6 2.7 7.8 9.6 1.2 1 0 0 1 1 1 0 SPX domain DOPA_dioxygen PF08883.11 RLN91673.1 - 1.1e-29 102.8 0.2 1.6e-29 102.2 0.2 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family G-alpha PF00503.20 RLN91674.1 - 4.9e-57 193.7 0.3 6.5e-57 193.3 0.3 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 RLN91674.1 - 7.1e-08 32.1 2.3 0.00026 20.5 0.0 2.8 2 1 0 3 3 3 2 ADP-ribosylation factor family AAA_29 PF13555.6 RLN91674.1 - 0.029 14.1 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 RLN91674.1 - 0.037 14.2 0.2 5.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 RLN91674.1 - 0.04 13.3 0.1 0.075 12.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 RLN91674.1 - 0.056 13.2 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 RLN91674.1 - 0.1 12.0 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family RabGAP-TBC PF00566.18 RLN91676.1 - 2.9e-41 141.5 3.0 1.4e-26 93.5 2.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain C2 PF00168.30 RLN91676.1 - 4.9e-07 30.0 0.0 1.5e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 C2 domain DTHCT PF08070.11 RLN91676.1 - 0.16 12.7 1.6 0.35 11.6 1.6 1.6 1 0 0 1 1 1 0 DTHCT (NUC029) region Es2 PF09751.9 RLN91677.1 - 2.5e-30 106.6 6.6 4.8e-20 72.7 1.6 2.6 1 1 1 2 2 2 2 Nuclear protein Es2 IBR PF01485.21 RLN91677.1 - 1.9e-12 47.2 48.3 2.5e-08 34.0 12.0 4.4 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain Pyr_redox_2 PF07992.14 RLN91677.1 - 3.8e-05 23.1 1.7 0.00096 18.5 0.9 3.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RLN91677.1 - 0.061 12.5 0.1 0.061 12.5 0.1 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 RLN91677.1 - 0.22 10.7 3.7 4.1 6.6 0.5 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ATP-synt_Eps PF04627.13 RLN91678.1 - 8e-17 61.0 0.2 1.1e-16 60.5 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Wyosine_form PF08608.12 RLN91679.1 - 2e-26 92.1 0.0 5.1e-26 90.8 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 RLN91679.1 - 1e-22 81.3 0.0 1.8e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 RLN91679.1 - 4.1e-18 66.0 1.0 4.1e-18 66.0 1.0 3.1 2 1 0 2 2 2 1 Flavodoxin Senescence_reg PF04520.13 RLN91679.1 - 5.7 7.7 11.3 7.5 7.4 0.5 2.8 3 0 0 3 3 3 0 Senescence regulator NDK PF00334.19 RLN91680.1 - 8.1e-30 103.6 0.0 3e-27 95.3 0.0 2.2 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 RLN91680.1 - 0.0016 18.2 0.0 0.0078 16.0 0.0 2.0 1 1 0 1 1 1 1 DUF1126 PH-like domain XPG_N PF00752.17 RLN91681.1 - 1.9e-28 98.9 0.0 3.3e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 RLN91681.1 - 1.8e-27 95.5 0.0 3.5e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 RLN91681.1 - 0.00057 20.4 0.0 0.0015 19.1 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Aldedh PF00171.22 RLN91682.1 - 2e-175 583.7 0.0 2.3e-175 583.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RNA_pol_Rpb2_45 PF10385.9 RLN91682.1 - 0.12 12.7 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase beta subunit external 1 domain DUF2884 PF11101.8 RLN91682.1 - 0.14 11.7 0.1 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) FH2 PF02181.23 RLN91683.1 - 1.9e-36 126.0 0.1 1.9e-23 83.2 0.1 2.2 1 1 1 2 2 2 2 Formin Homology 2 Domain FYVE PF01363.21 RLN91683.1 - 1.8e-09 37.6 8.7 3.6e-09 36.6 8.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger GOLD_2 PF13897.6 RLN91683.1 - 7.7e-09 36.2 3.5 0.03 14.8 1.1 4.3 3 1 0 3 3 3 2 Golgi-dynamics membrane-trafficking CCDC53 PF10152.9 RLN91683.1 - 2.1e-08 34.7 0.3 7e-08 33.0 0.1 2.0 2 0 0 2 2 2 1 Subunit CCDC53 of WASH complex FYVE_2 PF02318.16 RLN91683.1 - 0.0013 19.0 6.5 0.0025 18.0 5.7 1.9 2 0 0 2 2 2 1 FYVE-type zinc finger RUN PF02759.19 RLN91683.1 - 0.0046 16.9 0.0 0.014 15.4 0.0 1.8 1 0 0 1 1 1 1 RUN domain Eapp_C PF10238.9 RLN91683.1 - 4.2 7.4 7.0 0.87 9.6 2.7 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein His_Phos_2 PF00328.22 RLN91684.1 - 5.5e-09 35.9 0.0 4.2e-06 26.4 0.0 3.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ank_2 PF12796.7 RLN91686.1 - 1.2e-19 70.6 0.1 2.5e-05 24.8 0.2 3.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN91686.1 - 8.2e-18 64.5 0.2 0.00028 21.4 0.0 5.7 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN91686.1 - 1.8e-17 63.2 1.0 1.9e-05 24.8 0.0 5.5 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 RLN91686.1 - 3.6e-14 52.5 2.5 0.27 11.8 0.0 6.5 7 1 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 RLN91686.1 - 3.6e-13 48.4 0.3 0.65 10.7 0.0 6.9 7 0 0 7 7 7 3 Ankyrin repeat DDE_1 PF03184.19 RLN91689.1 - 3.1e-09 36.7 0.0 3.6e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Tub_N PF16322.5 RLN91690.1 - 0.056 13.8 6.7 0.096 13.1 6.7 1.4 1 0 0 1 1 1 0 Tubby N-terminal HypA PF01155.19 RLN91690.1 - 0.057 13.4 0.2 0.12 12.4 0.2 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TFIIE_alpha PF02002.17 RLN91690.1 - 0.059 13.2 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 TFIIE alpha subunit Arm PF00514.23 RLN91692.1 - 5.2e-12 45.4 28.6 0.01 15.8 0.2 11.1 12 0 0 12 12 12 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN91692.1 - 5.5e-10 39.5 13.2 8.3e-05 22.9 0.6 4.9 3 2 3 6 6 6 3 HEAT repeats HEAT_EZ PF13513.6 RLN91692.1 - 4.8e-08 33.3 18.2 0.0045 17.5 0.2 6.6 4 2 2 6 6 6 4 HEAT-like repeat RICTOR_V PF14668.6 RLN91692.1 - 6.1e-07 29.6 1.7 0.012 15.9 0.2 3.9 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, domain 5 KAP PF05804.12 RLN91692.1 - 0.00039 18.7 0.3 0.29 9.2 0.0 3.4 3 1 1 4 4 4 2 Kinesin-associated protein (KAP) Adaptin_N PF01602.20 RLN91692.1 - 0.0012 17.6 1.7 0.018 13.6 0.0 2.9 3 1 0 3 3 3 1 Adaptin N terminal region Cnd1 PF12717.7 RLN91692.1 - 0.0032 17.5 4.5 2.1 8.4 0.2 3.7 2 2 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.14 RLN91692.1 - 0.0046 16.3 0.5 0.089 12.1 0.2 3.0 2 1 0 3 3 3 1 V-ATPase subunit H HEAT PF02985.22 RLN91692.1 - 0.033 14.4 20.7 0.95 9.9 0.2 7.0 8 0 0 8 8 8 0 HEAT repeat Proteasom_PSMB PF10508.9 RLN91692.1 - 0.32 9.4 2.8 0.2 10.1 0.3 1.8 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit Pkinase PF00069.25 RLN91693.1 - 2.3e-07 30.4 0.0 8.7e-07 28.6 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase PF00069.25 RLN91694.1 - 2.9e-10 40.0 0.0 4.7e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain P33MONOX PF15302.6 RLN91694.1 - 0.017 14.9 0.2 0.017 14.9 0.2 1.7 2 0 0 2 2 2 0 P33 mono-oxygenase Pkinase_Tyr PF07714.17 RLN91694.1 - 0.02 14.2 0.0 0.038 13.3 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase MADF_DNA_bdg PF10545.9 RLN91696.1 - 0.075 13.4 1.1 0.18 12.1 0.1 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like LRR_6 PF13516.6 RLN91696.1 - 0.13 12.3 2.9 23 5.4 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat ABM PF03992.16 RLN91697.1 - 9.6e-05 22.4 0.1 0.00013 22.0 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase GRIP PF01465.20 RLN91698.1 - 1.8e-15 56.5 0.4 5.8e-15 54.9 0.4 2.0 1 0 0 1 1 1 1 GRIP domain NapD PF03927.13 RLN91698.1 - 0.015 15.3 0.4 0.77 9.8 0.4 4.4 1 0 0 1 1 1 0 NapD protein ABM PF03992.16 RLN91700.1 - 7.2e-06 26.0 0.2 1e-05 25.5 0.2 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DNA_pol_B_exo1 PF03104.19 RLN91700.1 - 0.022 13.9 0.3 0.024 13.8 0.3 1.0 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain Tyrosinase PF00264.20 RLN91701.1 - 3.4e-12 47.1 0.0 1e-11 45.5 0.0 1.7 1 1 0 1 1 1 1 Common central domain of tyrosinase RNA_pol_Rpb4 PF03874.16 RLN91702.1 - 4.2e-17 62.6 0.3 4.2e-17 62.6 0.3 1.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 SBE2 PF17076.5 RLN91702.1 - 0.0045 15.3 0.0 0.0048 15.2 0.0 1.0 1 0 0 1 1 1 1 SBE2, cell-wall formation DUF2757 PF10955.8 RLN91702.1 - 0.037 14.3 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) RRM_1 PF00076.22 RLN91704.1 - 2.9e-23 81.5 0.0 2.1e-17 62.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 RLN91704.1 - 8.1e-14 52.5 0.0 2.2e-13 51.1 0.0 1.8 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_7 PF16367.5 RLN91704.1 - 0.15 12.2 0.0 0.86 9.8 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif ATP-sulfurylase PF01747.17 RLN91705.1 - 4e-57 193.1 0.0 6.7e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase Pyrophosphatase PF00719.19 RLN91705.1 - 1.1e-39 135.8 0.1 1.8e-39 135.1 0.1 1.4 1 0 0 1 1 1 1 Inorganic pyrophosphatase PUA_2 PF14306.6 RLN91705.1 - 1.2e-32 112.8 0.0 6.2e-32 110.5 0.0 2.2 2 0 0 2 2 2 1 PUA-like domain APS_kinase PF01583.20 RLN91705.1 - 1e-28 100.2 0.0 1.8e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase Peptidase_M17 PF00883.21 RLN91706.1 - 4.4e-55 187.1 0.1 5e-55 187.0 0.1 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain DUF3672 PF12421.8 RLN91706.1 - 0.079 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Fibronectin type III protein TMEM89 PF15098.6 RLN91707.1 - 0.0046 17.1 1.7 0.0059 16.8 0.1 2.0 2 0 0 2 2 2 1 TMEM89 protein family UPF0182 PF03699.13 RLN91708.1 - 4 5.5 12.9 0.086 11.0 6.3 1.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) zf-RING_2 PF13639.6 RLN91710.1 - 4.1e-06 27.0 1.5 4.1e-06 27.0 1.5 2.7 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 RLN91710.1 - 5.1e-06 26.1 1.2 0.0017 18.0 0.2 2.7 2 0 0 2 2 2 2 RING-like zinc finger PX PF00787.24 RLN91710.1 - 1.7e-05 24.7 0.1 3.5e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 PX domain zf-C3HC4_2 PF13923.6 RLN91710.1 - 3.2e-05 23.7 3.0 3.2e-05 23.7 3.0 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN91710.1 - 5.7e-05 23.3 6.4 0.00058 20.1 6.4 2.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RLN91710.1 - 0.00012 22.0 4.5 0.002 18.0 4.5 2.4 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RLN91710.1 - 0.0013 18.8 3.2 0.0019 18.2 0.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RLN91710.1 - 0.0049 16.7 6.6 0.025 14.5 6.7 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 RLN91710.1 - 0.11 12.3 1.9 1.3 8.9 0.7 2.6 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 RLN91710.1 - 0.17 12.0 0.3 0.17 12.0 0.3 2.7 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RLN91710.1 - 0.38 10.6 3.9 11 6.0 2.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1604 PF07713.13 RLN91711.1 - 2.4e-33 113.8 0.4 2.4e-33 113.8 0.4 3.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 RLN91711.1 - 1.3e-07 31.3 0.1 3.9e-07 29.9 0.1 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 RLN91711.1 - 0.0089 16.1 0.2 0.0089 16.1 0.2 3.0 2 1 0 2 2 2 1 G-patch domain RRM_1 PF00076.22 RLN91712.1 - 5.2e-36 122.3 0.0 4.8e-18 64.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN91712.1 - 3.8e-07 30.1 0.0 0.035 14.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif DTHCT PF08070.11 RLN91712.1 - 6.9e-05 23.5 84.0 0.41 11.4 13.3 4.2 1 1 3 4 4 4 4 DTHCT (NUC029) region HC2 PF07382.11 RLN91712.1 - 0.0039 17.3 53.7 0.011 15.8 53.7 1.8 1 1 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Treacle PF03546.14 RLN91712.1 - 0.017 14.0 82.4 0.14 10.9 64.7 2.5 1 1 1 2 2 2 0 Treacher Collins syndrome protein Treacle Nup35_RRM_2 PF14605.6 RLN91712.1 - 0.063 13.3 0.0 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif GOLD_2 PF13897.6 RLN91715.1 - 3.3e-05 24.4 1.2 0.0039 17.7 0.0 2.8 2 1 1 3 3 3 1 Golgi-dynamics membrane-trafficking HOOK PF05622.12 RLN91715.1 - 7.5e-05 21.1 7.1 0.0001 20.7 7.1 1.1 1 0 0 1 1 1 1 HOOK protein TMCO5 PF14992.6 RLN91715.1 - 0.04 13.5 5.1 0.054 13.1 5.1 1.2 1 0 0 1 1 1 0 TMCO5 family DUF4407 PF14362.6 RLN91715.1 - 0.04 13.3 2.1 0.05 13.0 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAS PF13851.6 RLN91715.1 - 0.05 13.0 6.4 0.073 12.4 6.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FlxA PF14282.6 RLN91715.1 - 0.056 13.4 10.0 0.097 12.7 10.0 1.5 1 0 0 1 1 1 0 FlxA-like protein CCM2_C PF16545.5 RLN91715.1 - 0.094 13.2 0.1 0.19 12.3 0.1 1.5 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology Phage_GP20 PF06810.11 RLN91715.1 - 0.13 12.0 4.7 0.2 11.4 4.7 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 Med21 PF11221.8 RLN91715.1 - 0.16 12.2 8.9 0.23 11.7 8.8 1.3 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Exonuc_VII_L PF02601.15 RLN91715.1 - 0.22 11.0 2.5 0.24 10.9 2.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4349 PF14257.6 RLN91715.1 - 0.28 10.6 5.3 0.46 9.9 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF3573 PF12097.8 RLN91715.1 - 0.35 9.6 1.8 0.48 9.2 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF1993 PF09351.10 RLN91715.1 - 0.72 10.0 3.6 1.4 9.0 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) THOC7 PF05615.13 RLN91715.1 - 2.5 8.4 11.1 1.4 9.3 2.6 2.5 1 1 1 2 2 2 0 Tho complex subunit 7 Suf PF05843.14 RLN91716.1 - 1.7e-47 162.9 0.2 7.6e-44 150.9 0.0 3.6 3 1 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_19 PF14559.6 RLN91716.1 - 3.4e-05 24.3 8.6 0.023 15.2 0.7 4.5 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 RLN91716.1 - 7.1e-05 23.3 1.2 7.1e-05 23.3 1.2 6.9 6 2 2 8 8 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 RLN91716.1 - 0.0001 22.1 6.8 0.1 12.8 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN91716.1 - 0.00074 19.5 0.1 0.2 11.9 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN91716.1 - 0.00093 19.7 3.7 3.2 8.6 0.0 5.2 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN91716.1 - 0.0022 18.6 1.1 0.0022 18.6 1.1 4.2 5 1 1 6 6 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN91716.1 - 0.022 15.1 0.3 5.9 7.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat 23S_rRNA_IVP PF05635.11 RLN91716.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein TPR_12 PF13424.6 RLN91716.1 - 1.5 9.2 6.4 2.1 8.7 1.9 3.3 2 1 2 4 4 3 0 Tetratricopeptide repeat MSP1_C PF07462.11 RLN91716.1 - 2.9 6.5 6.2 4.4 5.9 6.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SDA1 PF05285.12 RLN91717.1 - 1 8.7 8.0 1.1 8.6 8.0 1.2 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 RLN91717.1 - 4.8 6.4 11.2 5.1 6.3 10.2 1.6 2 0 0 2 2 2 0 NOA36 protein Astro_capsid_p PF12226.8 RLN91717.1 - 8.1 5.5 10.0 9.4 5.3 10.0 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein UN_NPL4 PF11543.8 RLN91718.1 - 3.3e-11 43.5 0.0 6.3e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 ubiquitin PF00240.23 RLN91718.1 - 0.0024 17.6 0.0 0.0052 16.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family YukD PF08817.10 RLN91718.1 - 0.078 13.7 0.0 0.13 13.0 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD DUF3523 PF12037.8 RLN91719.1 - 4.5e-97 324.6 27.6 6.1e-97 324.1 27.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 RLN91719.1 - 1.3e-22 80.6 0.0 3.8e-22 79.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN91719.1 - 1.2e-05 25.8 4.7 0.00036 21.0 0.2 3.7 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 RLN91719.1 - 2.9e-05 23.9 0.3 0.00034 20.4 0.0 2.7 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RLN91719.1 - 0.00083 19.4 0.9 0.013 15.5 0.1 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 RLN91719.1 - 0.0022 18.2 0.0 0.0022 18.2 0.0 2.5 2 2 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RLN91719.1 - 0.0041 17.4 9.1 0.017 15.4 0.0 3.6 3 2 1 5 5 5 1 AAA domain AAA_lid_3 PF17862.1 RLN91719.1 - 0.0041 16.9 1.1 0.013 15.3 0.1 2.3 2 0 0 2 2 2 1 AAA+ lid domain Mg_chelatase PF01078.21 RLN91719.1 - 0.0049 16.3 0.1 0.015 14.7 0.1 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RLN91719.1 - 0.0074 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 RLN91719.1 - 0.019 15.0 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 RLN91719.1 - 0.02 14.6 0.0 0.083 12.6 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 RLN91719.1 - 0.026 15.1 0.0 0.026 15.1 0.0 3.0 2 2 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RLN91719.1 - 0.035 14.5 0.0 0.14 12.5 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 RLN91719.1 - 0.2 11.4 0.0 0.2 11.4 0.0 3.0 2 1 0 2 2 1 0 AAA domain V-ATPase_G PF03179.15 RLN91720.1 - 0.0059 17.1 4.5 0.0059 17.1 4.5 2.2 1 1 1 2 2 2 1 Vacuolar (H+)-ATPase G subunit SCAB_CC PF16712.5 RLN91720.1 - 0.15 11.9 7.5 2.1 8.1 4.5 2.3 2 0 0 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein Apolipoprotein PF01442.18 RLN91720.1 - 1.9 8.3 16.3 26 4.6 15.5 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain AF-4 PF05110.13 RLN91721.1 - 1.4 6.9 7.8 0.03 12.4 1.4 1.3 2 0 0 2 2 2 0 AF-4 proto-oncoprotein CAF1A PF12253.8 RLN91721.1 - 2 8.6 11.8 0.32 11.2 3.9 2.8 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A Pep1_7 PF17232.2 RLN91721.1 - 2.9 8.4 5.9 3.5 8.2 1.9 2.8 3 0 0 3 3 3 0 Elicitor peptide 1-7 DNA_pol_phi PF04931.13 RLN91721.1 - 3.2 5.7 15.6 4.9 5.1 15.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 RLN91721.1 - 5.1 7.5 19.5 5.9 7.3 13.6 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CENP-F_leu_zip PF10473.9 RLN91722.1 - 0.27 11.2 50.9 0.88 9.6 1.8 3.7 4 0 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Exonuc_VII_L PF02601.15 RLN91722.1 - 1.5 8.3 36.1 0.83 9.2 0.9 3.2 3 0 0 3 3 3 0 Exonuclease VII, large subunit C2 PF00168.30 RLN91723.1 - 2.8e-40 136.8 0.0 3.2e-14 53.1 0.0 3.6 3 0 0 3 3 3 3 C2 domain EF-hand_7 PF13499.6 RLN91723.1 - 2e-24 85.8 12.6 9.2e-13 48.5 1.4 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN91723.1 - 5.4e-22 75.7 14.0 5.9e-07 28.6 0.1 5.4 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 RLN91723.1 - 1.2e-18 65.3 11.0 5.2e-06 26.0 0.4 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 RLN91723.1 - 2e-15 56.4 15.4 1.9e-08 34.0 0.3 4.6 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 RLN91723.1 - 7.1e-14 50.6 9.2 0.0002 20.7 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 RLN91723.1 - 1.2e-06 28.8 1.0 0.00093 19.5 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 RLN91723.1 - 7.8e-06 26.2 0.2 0.036 14.4 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RLN91723.1 - 0.0015 18.5 2.2 2.9 7.9 0.1 3.3 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand PX PF00787.24 RLN91724.1 - 0.002 18.1 0.0 0.0085 16.1 0.0 2.0 2 0 0 2 2 2 1 PX domain RepB PF07506.11 RLN91726.1 - 0.0039 17.3 1.6 0.034 14.2 1.0 2.7 2 0 0 2 2 2 1 RepB plasmid partitioning protein TFIIE-A_C PF11521.8 RLN91726.1 - 0.4 11.0 4.4 0.96 9.8 4.4 1.6 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha MIP PF00230.20 RLN91727.1 - 6.8e-06 25.9 4.5 7.8e-06 25.8 4.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein ketoacyl-synt PF00109.26 RLN91727.1 - 0.0084 15.7 0.1 0.0091 15.6 0.1 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain CHASE3 PF05227.13 RLN91728.1 - 0.41 10.6 8.3 0.58 10.1 8.3 1.2 1 0 0 1 1 1 0 CHASE3 domain SCO1-SenC PF02630.14 RLN91729.1 - 4.1e-44 149.8 0.0 5.2e-44 149.4 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 RLN91729.1 - 0.0021 18.0 0.0 0.0032 17.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 RLN91729.1 - 0.0091 16.3 0.0 0.034 14.5 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like NatB_MDM20 PF09797.9 RLN91730.1 - 3.7e-60 203.9 8.4 3.7e-60 203.9 8.4 2.0 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit SCO1-SenC PF02630.14 RLN91730.1 - 2.6e-06 27.4 0.0 1.8e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 SCO1/SenC Ran_BP1 PF00638.18 RLN91730.1 - 0.0012 19.1 0.1 0.0045 17.3 0.1 2.1 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 RLN91730.1 - 0.0048 17.5 5.7 0.0048 17.5 5.7 4.1 3 2 0 3 3 3 1 NUP50 (Nucleoporin 50 kDa) TPR_19 PF14559.6 RLN91730.1 - 0.13 12.8 0.0 0.13 12.8 0.0 4.1 5 1 1 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.32 RLN91731.1 - 8.3e-05 23.3 0.6 0.0091 16.8 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Med7 PF05983.11 RLN91732.1 - 2.4e-29 102.8 8.5 7.7e-27 94.6 8.5 2.7 1 1 0 1 1 1 1 MED7 protein Med4 PF10018.9 RLN91732.1 - 0.044 13.5 0.6 0.064 12.9 0.6 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF3384 PF11864.8 RLN91732.1 - 0.071 12.0 0.1 0.097 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) Mpv17_PMP22 PF04117.12 RLN91733.1 - 9.2e-24 83.5 1.8 1.4e-23 82.9 1.5 1.5 1 1 0 1 1 1 1 Mpv17 / PMP22 family ETC_C1_NDUFA4 PF04800.12 RLN91734.1 - 0.1 12.9 1.1 0.37 11.1 1.1 2.0 1 0 0 1 1 1 0 ETC complex I subunit conserved region ADIP PF11559.8 RLN91734.1 - 0.69 10.0 43.6 0.22 11.6 15.0 3.3 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Cyclin PF08613.11 RLN91734.1 - 2 8.8 9.7 8.5 6.7 0.0 3.5 4 1 0 4 4 4 0 Cyclin TMEM171 PF15471.6 RLN91734.1 - 2.5 7.0 4.2 2.4 7.0 0.2 2.2 2 0 0 2 2 2 0 Transmembrane protein family 171 ATG16 PF08614.11 RLN91734.1 - 7.9 6.6 53.0 0.073 13.3 31.7 3.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF773 PF05600.12 RLN91735.1 - 0.027 13.2 5.4 2.5 6.7 5.1 2.1 2 0 0 2 2 2 0 CDK5 regulatory subunit-associated protein 3 FYVE PF01363.21 RLN91736.1 - 3.9e-18 65.3 7.2 6.2e-18 64.7 7.2 1.3 1 0 0 1 1 1 1 FYVE zinc finger PhnA_Zn_Ribbon PF08274.12 RLN91736.1 - 0.092 12.7 1.3 0.23 11.4 1.3 1.7 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zf-RING_5 PF14634.6 RLN91736.1 - 0.18 11.8 8.5 0.83 9.7 8.9 1.9 1 1 1 2 2 2 0 zinc-RING finger domain Ysc84 PF04366.12 RLN91737.1 - 5.5e-43 145.8 0.1 6.7e-43 145.5 0.1 1.1 1 0 0 1 1 1 1 Las17-binding protein actin regulator Oxidored_FMN PF00724.20 RLN91739.1 - 1.2e-70 238.5 0.0 1.4e-70 238.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 RLN91739.1 - 0.021 14.2 0.0 0.13 11.7 0.0 2.1 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel VPS9 PF02204.18 RLN91740.1 - 2.4e-15 56.6 0.0 3.9e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PH PF00169.29 RLN91740.1 - 5.8e-11 42.8 0.0 1.1e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN91740.1 - 0.00021 21.7 0.2 0.0005 20.5 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 RLN91740.1 - 0.001 19.3 0.1 0.0026 18.0 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Pex24p PF06398.11 RLN91740.1 - 0.012 14.6 0.4 0.055 12.5 0.4 1.9 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin zf-C2H2 PF00096.26 RLN91742.1 - 1.8e-19 69.0 22.5 1.7e-06 28.1 0.6 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN91742.1 - 3.2e-14 52.4 20.3 0.0014 19.3 0.5 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RLN91742.1 - 6.3e-09 35.9 27.5 4.3e-06 26.9 2.1 5.5 5 1 0 5 5 5 2 Zinc-finger double domain zf-C2H2_3rep PF18868.1 RLN91742.1 - 0.014 16.1 0.5 0.014 16.1 0.5 2.2 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 RLN91742.1 - 0.016 15.2 0.5 0.016 15.2 0.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 RLN91742.1 - 0.018 15.2 5.4 1.9 8.6 0.8 3.2 1 1 2 3 3 3 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 RLN91742.1 - 0.044 13.6 15.2 0.33 10.8 0.3 3.8 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 RLN91742.1 - 0.048 13.4 0.2 0.048 13.4 0.2 4.2 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 RLN91742.1 - 0.17 12.2 9.4 3.2 8.1 0.4 3.4 1 1 3 4 4 4 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 RLN91742.1 - 0.25 12.0 6.0 0.77 10.4 0.1 3.1 1 1 3 4 4 4 0 FOXP coiled-coil domain DUF4729 PF15866.5 RLN91742.1 - 0.3 10.4 6.1 2.7 7.3 0.1 3.1 2 2 2 4 4 4 0 Domain of unknown function (DUF4729) zf-C2H2_jaz PF12171.8 RLN91742.1 - 0.61 10.4 7.8 1.3 9.4 0.1 3.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 RLN91742.1 - 0.65 9.8 5.4 0.42 10.5 0.7 2.7 2 1 1 3 3 3 0 GAGA factor DUF1827 PF08860.10 RLN91744.1 - 0.048 13.9 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1827) KASH_CCD PF14662.6 RLN91744.1 - 0.13 12.1 8.0 0.041 13.7 4.8 1.7 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH BLOC1_2 PF10046.9 RLN91744.1 - 0.16 12.3 3.3 20 5.6 2.0 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMPIT PF07851.13 RLN91744.1 - 1.4 8.1 4.1 2.5 7.2 4.1 1.4 1 0 0 1 1 1 0 TMPIT-like protein CbiX PF01903.17 RLN91745.1 - 6.3e-07 29.7 0.1 9.1e-05 22.7 0.1 3.6 3 2 0 3 3 3 1 CbiX F420_oxidored PF03807.17 RLN91745.1 - 0.088 13.4 0.0 0.26 11.9 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MFS_1_like PF12832.7 RLN91746.1 - 5.2e-66 223.1 20.5 1.5e-65 221.6 20.5 1.6 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RLN91746.1 - 2.8e-23 82.4 25.7 3e-21 75.7 24.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 RLN91746.1 - 6e-16 58.2 15.6 9.1e-16 57.6 15.6 1.2 1 0 0 1 1 1 1 LacY proton/sugar symporter Nuc_H_symport PF03825.16 RLN91746.1 - 1.2e-14 54.1 19.9 2.2e-14 53.2 19.9 1.3 1 1 0 1 1 1 1 Nucleoside H+ symporter MFS_2 PF13347.6 RLN91746.1 - 6.6e-10 38.1 21.3 1e-06 27.6 11.3 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.13 RLN91746.1 - 0.00044 18.8 18.2 0.00087 17.8 18.2 1.5 1 1 0 1 1 1 1 Transmembrane secretion effector Pox_P21 PF05313.12 RLN91746.1 - 0.85 9.2 8.0 0.06 12.9 2.9 1.8 2 0 0 2 2 2 0 Poxvirus P21 membrane protein START PF01852.19 RLN91747.1 - 6.6e-07 28.9 1.0 1.2e-06 28.1 0.1 1.6 2 0 0 2 2 2 1 START domain FYVE PF01363.21 RLN91747.1 - 0.0025 17.9 1.1 0.0055 16.8 1.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger C1_2 PF03107.16 RLN91747.1 - 0.051 13.9 0.8 0.11 12.8 0.8 1.5 1 0 0 1 1 1 0 C1 domain zf-HIT PF04438.16 RLN91747.1 - 0.087 12.7 3.1 0.2 11.5 3.1 1.6 1 0 0 1 1 1 0 HIT zinc finger DNA_pol3_a_NI PF14480.6 RLN91747.1 - 0.15 12.1 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I TUDOR_5 PF18359.1 RLN91748.1 - 0.00012 21.7 0.3 0.00021 20.9 0.3 1.3 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 CLASP_N PF12348.8 RLN91748.1 - 0.0097 15.5 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 CLASP N terminal LBR_tudor PF09465.10 RLN91748.1 - 0.099 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Tudor_3 PF18115.1 RLN91748.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain MORN PF02493.20 RLN91749.1 - 0.0002 21.1 3.7 2.3 8.3 0.1 4.6 4 0 0 4 4 4 2 MORN repeat DUF4559 PF15112.6 RLN91749.1 - 0.5 10.0 9.0 0.7 9.5 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Bac_GDH PF05088.12 RLN91750.1 - 1.3e-14 52.8 0.0 1.8e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 RLN91750.1 - 0.03 14.2 0.0 0.07 13.0 0.0 1.6 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain HEAT_2 PF13646.6 RLN91751.1 - 0.0042 17.5 0.0 0.14 12.6 0.0 3.2 3 0 0 3 3 3 1 HEAT repeats Cnd3 PF12719.7 RLN91751.1 - 0.014 14.6 0.0 1.8 7.7 0.0 2.6 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Complex1_LYR PF05347.15 RLN91752.1 - 2.4e-08 33.9 4.4 1e-06 28.6 2.5 2.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 RLN91752.1 - 0.0067 17.1 0.2 0.0087 16.8 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like PsiA PF06952.11 RLN91752.1 - 0.045 13.0 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 PsiA protein Laminin_G_3 PF13385.6 RLN91753.1 - 1.9e-12 47.6 2.6 4.9e-12 46.2 2.6 1.7 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily F-box-like PF12937.7 RLN91753.1 - 0.0025 17.7 0.7 0.0061 16.4 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RLN91753.1 - 0.0052 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain Toxin_R_bind_N PF07953.12 RLN91753.1 - 0.073 12.8 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Clostridium neurotoxin, N-terminal receptor binding ChitinaseA_N PF08329.10 RLN91753.1 - 0.095 12.4 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Chitinase A, N-terminal domain Macro PF01661.21 RLN91754.1 - 1.7e-31 108.7 0.0 2.8e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Macro domain Laminin_G_3 PF13385.6 RLN91755.1 - 9.4e-12 45.3 0.4 2.4e-11 44.0 0.4 1.7 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily F-box-like PF12937.7 RLN91755.1 - 0.011 15.6 0.4 0.011 15.6 0.4 2.0 2 0 0 2 2 2 0 F-box-like BT1 PF03092.16 RLN91756.1 - 1.8e-20 72.7 11.3 5.9e-13 47.9 0.6 3.3 2 1 1 3 3 3 3 BT1 family ADH_zinc_N PF00107.26 RLN91757.1 - 4.8e-24 84.8 0.2 7.6e-24 84.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN91757.1 - 9.1e-16 59.1 0.0 1.9e-15 58.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN91757.1 - 8.7e-10 38.5 0.2 2.1e-09 37.2 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 RLN91757.1 - 0.0042 17.0 0.0 0.008 16.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 RLN91758.1 - 3e-25 88.7 0.1 5.4e-25 87.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN91758.1 - 1.2e-16 62.0 0.1 3.8e-16 60.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN91758.1 - 1.4e-08 34.6 0.7 4.8e-08 32.9 0.3 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain E1-N PF14463.6 RLN91758.1 - 0.033 14.0 2.0 0.064 13.1 0.3 2.0 1 1 1 2 2 2 0 E1 N-terminal domain Glyco_hydro_72 PF03198.14 RLN91759.1 - 1.9e-19 70.1 0.0 2.1e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase DIOX_N PF14226.6 RLN91760.1 - 1.3e-12 48.5 0.0 1.5e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Rav1p_C PF12234.8 RLN91761.1 - 6.2e-27 94.3 0.2 9.6e-27 93.7 0.2 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal Acetyltransf_1 PF00583.25 RLN91762.1 - 1.2e-09 38.4 0.6 9.4e-08 32.3 0.6 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RLN91762.1 - 2.9e-09 37.2 0.1 4.4e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RLN91762.1 - 1.6e-08 34.6 1.0 1.2e-06 28.5 1.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN91762.1 - 2.2e-05 24.4 0.5 0.18 11.8 0.3 2.2 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_CG PF14542.6 RLN91762.1 - 0.0003 20.9 0.2 0.00051 20.1 0.2 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 RLN91762.1 - 0.00061 19.3 0.0 0.00069 19.1 0.0 1.1 1 0 0 1 1 1 1 Putative acetyl-transferase PanZ PF12568.8 RLN91762.1 - 0.031 14.0 0.2 0.052 13.3 0.2 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ 2OG-FeII_Oxy PF03171.20 RLN91763.1 - 2.3e-06 28.0 0.0 3.4e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TcdA_TcdB_pore PF12920.7 RLN91765.1 - 1.3 7.2 2.9 3.3 5.9 3.0 1.5 2 0 0 2 2 2 0 TcdA/TcdB pore forming domain AAA_6 PF12774.7 RLN91766.1 - 1.6e-162 540.0 0.1 1.1e-160 534.0 0.0 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN91766.1 - 7.1e-124 413.9 0.5 7.1e-124 413.9 0.5 3.5 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RLN91766.1 - 1.8e-107 358.5 0.1 9e-107 356.2 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 RLN91766.1 - 9.1e-100 333.8 0.0 3e-98 328.9 0.0 3.2 4 0 0 4 4 4 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 RLN91766.1 - 1.1e-91 305.9 0.6 1.1e-91 305.9 0.6 2.5 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 RLN91766.1 - 1e-69 233.7 0.1 1.9e-65 219.8 0.0 3.7 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RLN91766.1 - 1.8e-47 161.2 0.0 5.2e-47 159.7 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 RLN91766.1 - 2e-47 161.9 12.7 4.3e-47 160.8 12.7 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RLN91766.1 - 5.7e-46 155.5 0.0 2.7e-42 143.6 0.0 3.2 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 RLN91766.1 - 4e-22 78.7 0.0 1.6e-21 76.8 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RLN91766.1 - 1.7e-18 66.6 0.0 1.5e-17 63.6 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 RLN91766.1 - 3.3e-17 62.8 0.0 0.00012 22.1 0.0 6.1 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RLN91766.1 - 7.8e-08 32.9 4.4 0.85 10.0 0.0 6.3 6 1 0 7 7 5 2 AAA ATPase domain AAA_22 PF13401.6 RLN91766.1 - 1.6e-07 31.7 0.0 0.71 10.1 0.0 4.9 5 0 0 5 5 4 2 AAA domain AAA PF00004.29 RLN91766.1 - 1.9e-07 31.6 0.2 0.24 11.8 0.0 5.1 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 RLN91766.1 - 1.2e-06 28.8 0.0 2.5 8.5 0.0 4.7 3 0 0 3 3 3 2 RNA helicase AAA_18 PF13238.6 RLN91766.1 - 9.9e-06 26.1 0.6 0.26 11.8 0.0 4.5 4 0 0 4 4 3 2 AAA domain NACHT PF05729.12 RLN91766.1 - 0.00011 22.1 0.0 0.49 10.3 0.0 3.6 3 0 0 3 3 3 1 NACHT domain AAA_29 PF13555.6 RLN91766.1 - 0.00017 21.2 0.1 0.066 13.0 0.0 3.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain T2SSE PF00437.20 RLN91766.1 - 0.00024 20.2 0.1 0.079 12.0 0.0 3.7 4 0 0 4 4 4 1 Type II/IV secretion system protein ABC_tran PF00005.27 RLN91766.1 - 0.0032 18.0 0.0 1.2 9.6 0.0 4.1 4 0 0 4 4 2 1 ABC transporter TsaE PF02367.17 RLN91766.1 - 0.0045 17.0 0.6 9.2 6.3 0.0 3.6 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 RLN91766.1 - 0.0065 16.2 0.1 0.25 11.0 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain DUF87 PF01935.17 RLN91766.1 - 0.0071 16.5 2.0 6.4 6.8 0.0 4.0 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_30 PF13604.6 RLN91766.1 - 0.0099 15.6 0.3 6.2 6.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 RLN91766.1 - 0.012 15.0 0.1 6.3 6.1 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 RLN91766.1 - 0.014 15.3 0.1 3.3 7.6 0.0 3.3 3 0 0 3 3 3 0 RsgA GTPase AAA_33 PF13671.6 RLN91766.1 - 0.02 15.1 0.0 3.4 7.8 0.0 3.4 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 RLN91766.1 - 0.031 14.0 0.0 11 5.7 0.0 3.2 3 0 0 3 3 3 0 Cytidylate kinase DUF815 PF05673.13 RLN91766.1 - 0.035 13.3 0.1 7.7 5.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 RLN91766.1 - 0.088 12.4 1.5 4.2 6.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 RLN91766.1 - 0.1 12.8 0.1 2.6 8.3 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Pkinase PF00069.25 RLN91768.1 - 5.7e-17 61.9 0.0 1.9e-16 60.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN91768.1 - 5.8e-07 29.1 0.2 3.2e-06 26.6 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 RLN91768.1 - 0.044 13.1 0.0 0.098 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bromodomain PF00439.25 RLN91769.1 - 3.7e-14 52.6 0.0 6.1e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain DNA_pol_A_exo1 PF01612.20 RLN91770.1 - 2.1e-05 24.3 0.0 0.13 11.9 0.0 2.3 2 0 0 2 2 2 2 3'-5' exonuclease AAA PF00004.29 RLN91771.1 - 0.00017 22.0 0.0 0.00032 21.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BACK PF07707.15 RLN91772.1 - 0.073 13.2 3.2 1.9 8.7 0.4 2.2 2 0 0 2 2 2 0 BTB And C-terminal Kelch BTB PF00651.31 RLN91772.1 - 0.14 12.4 0.7 8.4 6.7 0.2 2.1 1 1 1 2 2 2 0 BTB/POZ domain Cellulase PF00150.18 RLN91773.1 - 1.5e-21 77.1 2.2 1.9e-21 76.7 2.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Trp_oprn_chp PF09534.10 RLN91773.1 - 0.021 14.6 0.1 0.042 13.6 0.1 1.5 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Pilin_N PF07790.11 RLN91773.1 - 0.079 13.9 0.1 0.16 12.9 0.1 1.5 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal Pex14_N PF04695.13 RLN91773.1 - 0.11 13.1 2.1 0.22 12.2 2.1 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cellulase PF00150.18 RLN91774.1 - 6.8e-21 74.9 1.6 8.6e-21 74.6 1.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FtsL PF04999.13 RLN91774.1 - 0.092 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Cell division protein FtsL Cellulase PF00150.18 RLN91775.1 - 9.9e-26 90.8 0.8 1.2e-25 90.5 0.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) EMP70 PF02990.16 RLN91776.1 - 5.9e-76 256.2 0.0 7e-76 256.0 0.0 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 TraL PF07178.11 RLN91776.1 - 1 9.9 3.5 26 5.3 0.1 2.6 2 0 0 2 2 2 0 TraL protein Choline_transpo PF04515.12 RLN91777.1 - 5.6e-99 331.4 23.0 5.6e-99 331.4 23.0 2.8 2 1 2 4 4 4 1 Plasma-membrane choline transporter Stevor PF17410.2 RLN91777.1 - 0.24 10.9 3.0 0.65 9.5 3.0 1.8 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Sec63 PF02889.16 RLN91778.1 - 4.5e-75 252.1 0.0 1.4e-53 181.7 0.0 3.2 2 1 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 RLN91778.1 - 9.7e-55 185.0 9.7 4.1e-30 104.9 3.5 3.8 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 RLN91778.1 - 7.5e-23 81.4 0.1 3.2e-14 53.3 0.5 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RLN91778.1 - 2e-13 50.6 0.1 2e-06 28.1 0.0 3.8 3 1 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 RLN91778.1 - 3.6e-10 40.2 2.7 0.00011 22.4 0.4 4.0 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 RLN91778.1 - 3.5e-05 23.0 0.0 0.12 11.4 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_19 PF13245.6 RLN91778.1 - 0.00013 22.3 3.6 0.024 15.0 1.0 3.5 4 0 0 4 4 3 1 AAA domain AAA PF00004.29 RLN91778.1 - 0.00058 20.3 2.9 2 8.8 0.9 4.3 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 RLN91778.1 - 0.0017 17.9 0.2 0.94 9.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 RLN91778.1 - 0.0047 16.7 0.3 1.4 8.6 0.0 3.5 3 0 0 3 3 3 1 IstB-like ATP binding protein PhoH PF02562.16 RLN91778.1 - 0.011 15.2 0.0 2 7.8 0.1 2.5 2 0 0 2 2 2 0 PhoH-like protein Amidinotransf PF02274.17 RLN91778.1 - 0.011 14.8 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 Amidinotransferase Helicase_PWI PF18149.1 RLN91778.1 - 0.022 14.9 0.1 0.14 12.4 0.0 2.5 2 0 0 2 2 1 0 N-terminal helicase PWI domain UvrD-helicase PF00580.21 RLN91778.1 - 0.031 13.8 4.1 0.6 9.6 0.2 3.3 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain UTP25 PF06862.12 RLN91778.1 - 0.057 12.2 0.9 1.7 7.3 0.1 2.4 1 1 1 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Sigma54_activ_2 PF14532.6 RLN91778.1 - 0.15 12.1 3.4 22 5.2 0.0 3.3 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 RLN91778.1 - 3.2 7.5 21.6 0.22 11.3 0.4 5.6 4 2 1 6 6 6 0 AAA domain FYVE_2 PF02318.16 RLN91779.1 - 0.16 12.2 5.4 0.3 11.3 5.4 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 RLN91779.1 - 6 7.1 10.2 5.1 7.3 8.5 1.8 2 0 0 2 2 2 0 FYVE zinc finger adh_short PF00106.25 RLN91780.1 - 1.7e-15 57.0 0.7 2.5e-13 49.9 0.7 2.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN91780.1 - 6.8e-09 35.6 0.2 8.3e-06 25.5 0.2 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase TRP PF06011.12 RLN91781.1 - 8.5e-25 87.3 8.1 1.3e-24 86.8 8.1 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF973 PF06157.11 RLN91781.1 - 2.7 7.0 17.3 0.036 13.1 6.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF973) FYVE PF01363.21 RLN91785.1 - 0.18 12.0 5.1 0.39 10.9 5.1 1.6 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 RLN91785.1 - 1.1 9.5 6.3 0.5 10.6 3.6 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger FYVE_2 PF02318.16 RLN91786.1 - 0.16 12.2 5.4 0.34 11.1 5.4 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 RLN91786.1 - 6.5 7.0 10.2 5.8 7.1 8.5 1.9 2 0 0 2 2 2 0 FYVE zinc finger Cupin_8 PF13621.6 RLN91787.1 - 1.2e-52 179.1 0.1 1.7e-52 178.6 0.1 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 RLN91787.1 - 0.016 15.6 0.0 0.053 14.0 0.0 1.9 2 0 0 2 2 2 0 JmjC domain, hydroxylase Cupin_4 PF08007.12 RLN91787.1 - 0.023 14.2 0.1 0.042 13.3 0.1 1.3 1 0 0 1 1 1 0 Cupin superfamily protein PaaB PF06243.11 RLN91787.1 - 0.047 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Phenylacetic acid degradation B Glucosamine_iso PF01182.20 RLN91787.1 - 0.048 13.5 0.1 0.082 12.8 0.1 1.3 1 0 0 1 1 1 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sugar_tr PF00083.24 RLN91790.1 - 1.1e-115 387.1 23.0 1.1e-115 387.1 23.0 1.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN91790.1 - 1.4e-17 63.6 34.6 1.4e-17 63.6 34.6 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily FUN14 PF04930.15 RLN91790.1 - 1.7e-17 63.6 0.0 1.7e-17 63.6 0.0 2.7 3 0 0 3 3 3 1 FUN14 family FYVE PF01363.21 RLN91791.1 - 0.00031 20.8 6.2 0.00066 19.8 6.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN91791.1 - 0.069 13.4 2.9 0.15 12.3 2.9 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger zf-CRD PF17979.1 RLN91791.1 - 0.21 11.7 3.2 0.4 10.8 3.2 1.4 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions zf-AN1 PF01428.16 RLN91791.1 - 8.2 6.7 7.4 5.7 7.2 4.2 2.3 2 1 0 2 2 2 0 AN1-like Zinc finger FYVE_2 PF02318.16 RLN91792.1 - 0.00037 20.7 3.9 0.00037 20.7 3.9 1.7 2 0 0 2 2 2 1 FYVE-type zinc finger FYVE PF01363.21 RLN91792.1 - 0.0097 16.0 9.3 0.021 15.0 9.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger C1_1 PF00130.22 RLN91792.1 - 0.22 11.5 13.5 0.028 14.3 9.2 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-piccolo PF05715.13 RLN91792.1 - 2.2 8.5 6.0 5.3 7.3 6.0 1.6 1 0 0 1 1 1 0 Piccolo Zn-finger DZR PF12773.7 RLN91792.1 - 6 7.0 9.9 2.9e+02 1.6 9.9 2.5 1 1 0 1 1 1 0 Double zinc ribbon GlcNAc PF11397.8 RLN91793.1 - 1.4e-48 166.1 0.0 6.5e-39 134.4 0.0 2.4 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) zf-RING_2 PF13639.6 RLN91794.1 - 4.1e-12 46.2 8.6 4.1e-12 46.2 8.6 2.5 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN91794.1 - 2e-09 37.2 9.4 2e-09 37.2 9.4 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 RLN91794.1 - 5e-09 36.3 5.1 5e-09 36.3 5.1 3.6 4 0 0 4 4 4 1 zinc-ribbon zf-rbx1 PF12678.7 RLN91794.1 - 7.4e-07 29.4 12.2 5.1e-06 26.7 12.2 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RLN91794.1 - 9.3e-07 28.6 6.6 9.3e-07 28.6 6.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN91794.1 - 1.9e-05 24.3 6.4 3.9e-05 23.3 6.4 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 RLN91794.1 - 7e-05 22.8 2.5 0.0002 21.3 2.5 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 RLN91794.1 - 0.00014 21.8 8.0 0.00042 20.3 8.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN91794.1 - 0.00045 20.1 4.1 0.00045 20.1 4.1 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RLN91794.1 - 0.0011 18.8 2.6 0.0011 18.8 2.6 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 RLN91794.1 - 0.12 12.2 3.3 0.29 11.0 3.3 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Elf1 PF05129.13 RLN91794.1 - 0.21 11.7 4.0 8 6.6 1.0 2.7 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like HypA PF01155.19 RLN91794.1 - 0.26 11.3 8.7 2.5 8.1 3.0 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rad50_zn_hook PF04423.14 RLN91794.1 - 0.82 9.6 5.9 0.8 9.6 0.1 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif TF_Zn_Ribbon PF08271.12 RLN91794.1 - 6 6.5 10.1 2.6 7.6 2.4 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding HEAT PF02985.22 RLN91795.1 - 4.9e-33 110.3 30.0 0.0035 17.5 0.0 12.7 12 0 0 12 12 12 10 HEAT repeat HEAT_2 PF13646.6 RLN91795.1 - 3.7e-28 97.7 18.2 1.9e-09 37.8 0.0 7.7 3 2 4 7 7 7 6 HEAT repeats Vac14_Fab1_bd PF12755.7 RLN91795.1 - 1.8e-09 38.1 0.9 0.027 15.1 0.0 6.9 3 2 4 8 8 8 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 RLN91795.1 - 1.5e-07 31.6 9.3 9.7e-05 22.5 0.2 4.8 2 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 RLN91795.1 - 6.4e-07 29.8 27.0 0.024 15.2 0.6 8.6 4 3 6 10 10 10 4 HEAT-like repeat Adaptin_N PF01602.20 RLN91795.1 - 0.00064 18.4 10.2 0.011 14.3 2.4 4.0 2 1 1 3 3 3 2 Adaptin N terminal region IFRD PF05004.13 RLN91795.1 - 0.00078 18.6 1.5 0.0059 15.7 0.4 2.5 1 1 1 2 2 2 2 Interferon-related developmental regulator (IFRD) DRIM PF07539.12 RLN91795.1 - 0.0067 14.8 0.4 0.027 12.8 0.5 1.8 2 0 0 2 2 2 1 Down-regulated in metastasis PH PF00169.29 RLN91796.1 - 3.7e-44 149.5 1.4 2.7e-15 56.8 0.0 3.3 3 0 0 3 3 3 3 PH domain PH_8 PF15409.6 RLN91796.1 - 4.1e-14 52.6 3.5 1.1e-06 28.9 0.1 4.0 3 1 0 3 3 3 3 Pleckstrin homology domain PH_11 PF15413.6 RLN91796.1 - 4.4e-09 36.7 17.1 0.00058 20.2 0.6 5.6 3 3 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.6 RLN91796.1 - 2.9e-06 27.3 1.2 0.052 13.7 0.0 3.3 4 0 0 4 4 4 2 PH domain PH_9 PF15410.6 RLN91796.1 - 0.00011 22.5 0.9 1.3 9.4 0.0 4.5 4 2 0 4 4 4 1 Pleckstrin homology domain PDZ_6 PF17820.1 RLN91796.1 - 0.032 14.1 0.0 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 PDZ domain PH_13 PF16652.5 RLN91796.1 - 0.12 12.2 0.0 18 5.1 0.0 2.8 3 0 0 3 3 3 0 Pleckstrin homology domain PH_4 PF15404.6 RLN91796.1 - 0.15 11.9 1.4 4.6 7.0 0.1 2.5 1 1 1 2 2 2 0 Pleckstrin homology domain KAR9 PF08580.10 RLN91796.1 - 7.5 5.0 7.5 11 4.3 7.5 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 PLDc_2 PF13091.6 RLN91797.1 - 1.9e-17 63.4 0.1 1.4e-10 41.2 0.0 3.2 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.22 RLN91797.1 - 1.4e-15 56.8 1.3 8.7e-08 32.0 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif IMPDH PF00478.25 RLN91798.1 - 1.1e-10 41.1 0.1 1.2e-10 41.0 0.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain DUF3449 PF11931.8 RLN91800.1 - 2.4e-74 249.1 1.4 2.4e-74 249.1 1.4 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 RLN91800.1 - 1.7e-16 60.5 0.4 5.1e-16 59.0 0.4 1.8 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 RLN91800.1 - 1.1e-10 41.2 0.7 3.4e-10 39.6 0.1 2.3 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 RLN91800.1 - 9.3e-10 38.6 1.1 9.3e-10 38.6 1.1 2.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RLN91800.1 - 3.2e-09 36.9 1.4 3.2e-09 36.9 1.4 3.0 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 RLN91800.1 - 0.00038 20.7 3.2 0.0096 16.2 0.0 3.6 3 0 0 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 RLN91800.1 - 0.0083 16.2 2.8 0.032 14.3 0.1 3.1 2 0 0 2 2 2 1 DBF zinc finger zf-C2H2_4 PF13894.6 RLN91800.1 - 0.018 15.8 4.2 1.8 9.6 0.3 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger DUF917 PF06032.12 RLN91800.1 - 0.047 12.5 0.5 0.076 11.8 0.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF917) BEN PF10523.9 RLN91800.1 - 0.12 12.6 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 BEN domain DJ-1_PfpI PF01965.24 RLN91802.1 - 5.1e-32 110.9 0.6 6.4e-32 110.6 0.6 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Copine PF07002.16 RLN91804.1 - 1.3e-55 188.2 0.1 2.1e-55 187.5 0.1 1.3 1 0 0 1 1 1 1 Copine zf-C3HC4_3 PF13920.6 RLN91804.1 - 8.7e-09 35.1 8.9 1.4e-08 34.4 8.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN91804.1 - 7.9e-06 25.6 11.8 1.7e-05 24.6 11.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) YwiC PF14256.6 RLN91804.1 - 0.0076 16.6 3.0 0.0076 16.6 3.0 2.1 1 1 1 2 2 2 1 YwiC-like protein Bax1-I PF01027.20 RLN91804.1 - 0.023 14.5 4.1 0.039 13.8 4.1 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Prok-RING_4 PF14447.6 RLN91804.1 - 0.024 14.5 10.5 0.12 12.2 10.7 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 TerY_C PF15616.6 RLN91804.1 - 0.026 14.7 2.2 0.026 14.7 2.2 1.8 2 0 0 2 2 2 0 TerY-C metal binding domain vWA-TerF-like PF10138.9 RLN91804.1 - 0.039 14.1 0.2 0.12 12.5 0.2 1.8 1 1 0 1 1 1 0 vWA found in TerF C terminus zf-RING_2 PF13639.6 RLN91804.1 - 0.047 14.0 11.0 0.1 12.9 11.0 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 RLN91804.1 - 0.16 11.8 11.3 0.37 10.7 11.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RLN91804.1 - 0.16 12.1 5.6 0.58 10.4 5.8 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 RLN91804.1 - 0.83 9.7 12.1 5.1 7.1 12.6 2.0 1 1 1 2 2 2 0 zinc-RING finger domain Cys_rich_KTR PF14205.6 RLN91804.1 - 1.2 9.0 9.6 0.1 12.4 4.7 1.9 2 0 0 2 2 1 0 Cysteine-rich KTR zinc-ribbons_6 PF07191.12 RLN91804.1 - 2.3 8.3 9.2 4.6 7.3 9.2 1.5 1 0 0 1 1 1 0 zinc-ribbons zf-RING_UBOX PF13445.6 RLN91804.1 - 3.3 7.8 11.6 0.29 11.2 5.7 2.2 2 0 0 2 2 2 0 RING-type zinc-finger CxC6 PF18721.1 RLN91805.1 - 0.58 10.5 33.0 0.55 10.5 10.0 4.9 1 1 3 4 4 4 0 CxC6 like cysteine cluster associated with KDZ transposases VPS9 PF02204.18 RLN91806.1 - 1.7e-11 44.2 0.1 3.9e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain adh_short PF00106.25 RLN91807.1 - 1e-42 145.8 0.1 1.4e-42 145.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN91807.1 - 7.4e-25 87.9 0.0 1e-24 87.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN91807.1 - 5.4e-09 36.2 0.1 7.6e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 RLN91807.1 - 0.0063 16.4 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 RLN91807.1 - 0.028 13.8 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RLN91807.1 - 0.063 12.7 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 RLN91807.1 - 0.07 13.0 0.1 0.097 12.6 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.25 RLN91809.1 - 4.5e-61 206.5 0.0 5.4e-61 206.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN91809.1 - 8.9e-44 149.7 0.0 1.1e-43 149.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN91809.1 - 6.4e-07 29.0 0.0 4.1e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RLN91809.1 - 0.0002 20.2 0.0 0.00029 19.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN91809.1 - 0.059 13.3 0.2 0.26 11.2 0.0 1.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Tubulin_C PF03953.17 RLN91812.1 - 1.2e-21 77.2 0.0 1.6e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Glyco_hydro_30 PF02055.16 RLN91813.1 - 3.1e-81 273.1 0.3 4e-81 272.7 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Ricin_B_lectin PF00652.22 RLN91813.1 - 1.7e-10 41.2 3.4 1.3e-07 31.9 0.7 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Glyco_hydro_30C PF17189.4 RLN91813.1 - 1e-06 28.8 0.1 2.7e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 RLN91813.1 - 1.7e-06 27.5 0.0 3.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 RLN91813.1 - 1.3e-05 25.0 0.0 3e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 RicinB_lectin_2 PF14200.6 RLN91813.1 - 0.018 15.7 0.3 0.049 14.4 0.3 1.7 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like Kinesin PF00225.23 RLN91814.1 - 4.4e-103 344.7 0.1 4.4e-103 344.7 0.1 2.1 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 RLN91814.1 - 8.6e-24 84.2 0.1 8.6e-19 67.9 0.0 3.2 3 0 0 3 3 3 2 Microtubule binding Elf1 PF05129.13 RLN91816.1 - 1.6e-18 66.5 13.3 3.5e-09 36.6 0.9 2.8 2 1 0 2 2 2 2 Transcription elongation factor Elf1 like Stc1 PF12898.7 RLN91816.1 - 0.0044 17.5 4.7 0.2 12.3 1.6 2.1 2 0 0 2 2 2 2 Stc1 domain C1_4 PF07975.12 RLN91816.1 - 0.22 11.8 5.4 0.22 11.8 1.9 2.2 2 0 0 2 2 2 0 TFIIH C1-like domain UCH PF00443.29 RLN91817.1 - 1.6e-58 198.2 0.0 2.5e-58 197.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 RLN91817.1 - 3.2e-19 69.3 0.0 6.1e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 RLN91817.1 - 3.4e-10 40.0 0.0 0.00043 20.0 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase EF-hand_8 PF13833.6 RLN91817.1 - 0.00031 20.5 0.0 0.0011 18.8 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN91817.1 - 0.00032 20.1 0.1 0.00081 18.8 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 RLN91817.1 - 0.0027 17.5 0.1 0.0096 15.8 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 RLN91817.1 - 0.004 17.6 0.2 0.014 15.9 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN91817.1 - 0.0047 16.4 4.2 0.0049 16.3 0.2 2.5 2 0 0 2 2 2 1 EF hand ATP-synt_F6 PF05511.11 RLN91818.1 - 0.073 13.5 0.5 0.081 13.3 0.5 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Torus PF16131.5 RLN91819.1 - 3.3e-32 111.4 1.5 5.1e-32 110.8 0.3 2.0 2 0 0 2 2 2 1 Torus domain WW PF00397.26 RLN91819.1 - 7.5e-10 38.7 0.6 1.5e-09 37.8 0.6 1.5 1 0 0 1 1 1 1 WW domain RRM_1 PF00076.22 RLN91819.1 - 5.6e-07 29.3 0.0 9.9e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 RLN91819.1 - 6.1e-05 22.3 4.5 0.00012 21.3 4.5 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf_CCCH_4 PF18345.1 RLN91819.1 - 0.0078 16.2 3.0 0.02 15.0 3.0 1.8 1 0 0 1 1 1 1 Zinc finger domain Glyco_hyd_101C PF17451.2 RLN91819.1 - 0.084 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain TackOD1 PF18551.1 RLN91819.1 - 0.13 11.9 1.6 0.32 10.6 1.2 1.6 1 1 0 1 1 1 0 Thaumarchaeal output domain 1 zf-CCCH PF00642.24 RLN91819.1 - 0.16 11.9 4.1 0.3 11.0 4.1 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 RLN91819.1 - 0.54 10.1 6.5 1.2 9.0 6.5 1.6 1 0 0 1 1 1 0 CCCH-type zinc finger DUF1295 PF06966.12 RLN91820.1 - 6.3e-48 163.3 10.7 9.5e-48 162.8 10.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) OrfB_Zn_ribbon PF07282.11 RLN91820.1 - 1e-08 34.9 2.3 1.8e-08 34.2 2.3 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HTH_OrfB_IS605 PF12323.8 RLN91820.1 - 3.6e-08 32.8 3.5 1e-07 31.3 3.5 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain OrfB_IS605 PF01385.19 RLN91820.1 - 0.0027 17.9 0.1 0.0027 17.9 0.1 2.0 2 0 0 2 2 2 1 Probable transposase ICMT PF04140.14 RLN91820.1 - 0.022 15.2 0.0 0.095 13.1 0.0 2.1 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Vps52 PF04129.12 RLN91820.1 - 0.025 13.3 0.3 0.04 12.7 0.3 1.3 1 0 0 1 1 1 0 Vps52 / Sac2 family Steroid_dh PF02544.16 RLN91820.1 - 0.042 13.8 5.5 0.17 11.8 5.1 2.2 1 1 1 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase SOTI PF17079.5 RLN91820.1 - 0.13 12.7 3.5 0.089 13.2 0.7 2.1 2 1 0 3 3 3 0 Male-specific protein scotti Na_H_Exchanger PF00999.21 RLN91821.1 - 2.2e-35 122.2 40.0 3.1e-35 121.7 40.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pkinase PF00069.25 RLN91822.1 - 2.1e-71 240.4 0.0 2.8e-71 240.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN91822.1 - 3.2e-36 124.9 0.0 4.5e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN91822.1 - 0.0037 17.2 1.0 0.006 16.5 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN91822.1 - 0.007 15.2 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN91822.1 - 0.0081 15.5 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 RLN91822.1 - 0.039 13.5 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 RLN91823.1 - 8.7e-31 107.2 0.0 8.5e-16 58.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN91823.1 - 2.9e-12 46.4 0.1 2.8e-09 36.7 0.0 2.4 1 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 RLN91823.1 - 0.05 13.5 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SRR1 PF07985.12 RLN91824.1 - 1e-13 51.1 0.0 3.2e-13 49.5 0.0 1.9 1 0 0 1 1 1 1 SRR1 Ank_2 PF12796.7 RLN91825.1 - 1.1e-08 35.5 3.7 0.00096 19.7 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN91825.1 - 2.1e-05 24.5 0.3 1.8 9.4 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 RLN91825.1 - 3.6e-05 24.2 1.1 0.015 15.9 0.0 3.9 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN91825.1 - 0.019 15.2 0.3 1 9.8 0.0 3.4 3 1 1 4 4 4 0 Ankyrin repeats (many copies) ABC_tran_2 PF16949.5 RLN91825.1 - 0.06 12.2 0.0 0.06 12.2 0.0 1.0 1 0 0 1 1 1 0 Putative ATP-binding cassette SNF2_N PF00176.23 RLN91827.1 - 6.1e-65 219.2 0.1 1.3e-64 218.1 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN91827.1 - 1.7e-18 67.0 0.0 3.4e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN91827.1 - 1e-09 38.6 0.0 2.2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 RLN91827.1 - 1.6e-09 37.9 8.5 1.6e-09 37.9 8.5 3.8 2 1 1 3 3 2 1 HSA Beta_helix PF13229.6 RLN91827.1 - 4.6e-06 26.6 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Right handed beta helix region WW PF00397.26 RLN91827.1 - 6.4e-05 22.9 0.0 0.00016 21.7 0.0 1.7 1 0 0 1 1 1 1 WW domain F-box-like PF12937.7 RLN91827.1 - 0.00027 20.7 0.1 0.001 18.9 0.1 2.0 1 0 0 1 1 1 1 F-box-like ERCC3_RAD25_C PF16203.5 RLN91827.1 - 0.0021 17.3 0.0 0.0044 16.3 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 RLN91827.1 - 0.0021 17.9 0.0 0.0051 16.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase LRR_8 PF13855.6 RLN91827.1 - 0.031 14.0 0.3 0.21 11.4 0.0 2.4 1 1 1 2 2 2 0 Leucine rich repeat NosD PF05048.13 RLN91827.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) DUF1765 PF08578.10 RLN91828.1 - 0.073 13.5 1.2 0.2 12.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1765) cNMP_binding PF00027.29 RLN91829.1 - 9.8e-13 48.0 0.0 1.9e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN91829.1 - 7.1e-11 41.8 6.5 1.8e-10 40.5 6.5 1.7 1 1 0 1 1 1 1 Ion transport protein Pyr_redox_2 PF07992.14 RLN91830.1 - 6.4e-51 173.3 0.4 7.7e-51 173.1 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RLN91830.1 - 1.1e-21 77.1 0.7 1.4e-16 60.8 0.5 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 RLN91830.1 - 5e-10 39.2 0.0 2.3e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox_3 PF13738.6 RLN91830.1 - 1.9e-08 34.0 0.0 4.6e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 RLN91830.1 - 0.0008 18.6 1.5 1 8.3 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 RLN91830.1 - 0.011 16.0 0.0 0.13 12.5 0.1 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 RLN91830.1 - 0.015 15.7 0.0 3 8.3 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_oxidored PF12831.7 RLN91830.1 - 0.018 14.4 1.3 20 4.4 0.0 3.1 2 1 1 3 3 3 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 RLN91830.1 - 0.02 14.2 0.2 0.02 14.2 0.2 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 RLN91830.1 - 0.05 13.9 0.2 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.20 RLN91830.1 - 0.074 13.1 0.1 5.1 7.1 0.1 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 RLN91830.1 - 0.089 11.9 0.3 0.22 10.6 0.2 1.7 1 1 1 2 2 2 0 Glucose inhibited division protein A 2Fe-2S_thioredx PF01257.19 RLN91831.1 - 2e-61 206.1 0.1 2.4e-61 205.9 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF1636 PF07845.11 RLN91831.1 - 0.11 12.9 0.1 0.27 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1636) DnaJ PF00226.31 RLN91832.1 - 2e-13 50.2 0.6 2.8e-13 49.8 0.6 1.2 1 0 0 1 1 1 1 DnaJ domain SNARE PF05739.19 RLN91833.1 - 0.0025 17.8 0.7 0.018 15.0 0.1 2.4 2 0 0 2 2 2 1 SNARE domain DUF1664 PF07889.12 RLN91833.1 - 0.0032 17.5 8.0 0.32 11.0 4.2 3.1 1 1 0 2 2 2 2 Protein of unknown function (DUF1664) SKA1 PF07160.12 RLN91833.1 - 0.0039 17.1 1.7 0.0039 17.1 1.7 1.7 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 1 MCPsignal PF00015.21 RLN91833.1 - 0.0055 16.5 6.4 0.0055 16.5 6.4 2.1 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin_2 PF14523.6 RLN91833.1 - 0.022 15.1 5.6 1.6 9.1 0.7 2.6 2 1 0 2 2 2 0 Syntaxin-like protein FlaC_arch PF05377.11 RLN91833.1 - 0.024 15.0 1.6 0.11 12.9 0.2 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Trimer_CC PF08954.11 RLN91833.1 - 0.028 14.0 0.2 0.028 14.0 0.2 2.0 2 0 0 2 2 2 0 Trimerisation motif Phage_connect_1 PF05135.13 RLN91833.1 - 0.069 13.7 0.4 0.22 12.0 0.1 2.0 2 1 0 2 2 2 0 Phage gp6-like head-tail connector protein RasGAP_C PF03836.15 RLN91833.1 - 0.11 12.6 2.2 0.21 11.7 2.2 1.5 1 0 0 1 1 1 0 RasGAP C-terminus DUF948 PF06103.11 RLN91833.1 - 0.18 12.1 2.7 2.4 8.5 1.9 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 RLN91833.1 - 0.26 10.1 9.7 0.42 9.4 9.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin PF00804.25 RLN91833.1 - 0.44 10.2 11.0 0.099 12.3 5.9 2.4 2 1 1 3 3 3 0 Syntaxin Fib_alpha PF08702.10 RLN91833.1 - 0.47 10.6 4.1 1.4 9.1 4.0 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 RLN91833.1 - 0.62 10.1 4.0 0.53 10.3 0.5 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 RLN91833.1 - 5.4 7.4 7.7 1.1 9.6 1.7 2.4 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HA2 PF04408.23 RLN91834.1 - 6.9e-23 81.0 0.1 1.8e-22 79.6 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RLN91834.1 - 2.9e-15 56.4 0.0 3.3e-14 53.0 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 RLN91834.1 - 2.6e-12 47.1 0.1 5.7e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 RLN91834.1 - 2.8e-05 24.4 0.0 8.8e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 RLN91834.1 - 3.4e-05 23.7 0.0 9.1e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 RLN91834.1 - 0.0022 18.3 0.0 0.0061 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RLN91834.1 - 0.0058 16.4 0.1 0.018 14.8 0.1 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 RLN91834.1 - 0.028 13.5 0.0 0.061 12.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 RLN91834.1 - 0.047 13.2 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 RLN91834.1 - 0.1 12.0 0.0 0.25 10.8 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.6 RLN91834.1 - 0.12 12.9 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RLN91834.1 - 0.16 12.3 4.2 0.34 11.3 0.1 3.2 3 0 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.27 RLN91834.1 - 0.16 12.5 0.1 1.8 9.1 0.1 2.5 1 1 0 1 1 1 0 ABC transporter LRR_8 PF13855.6 RLN91835.1 - 9.8e-11 41.3 6.8 1e-06 28.4 0.1 3.8 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 RLN91835.1 - 8.2e-09 35.6 5.4 0.012 16.0 0.1 4.0 1 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN91835.1 - 5.5e-08 32.5 0.6 0.00077 19.0 0.1 2.6 1 1 1 2 2 2 2 Leucine-rich repeat Fib_alpha PF08702.10 RLN91835.1 - 0.34 11.1 5.0 0.96 9.6 4.1 2.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family LRR_1 PF00560.33 RLN91835.1 - 2 9.3 6.9 15 6.6 1.1 4.2 3 1 0 3 3 3 0 Leucine Rich Repeat TMPIT PF07851.13 RLN91835.1 - 5.4 6.2 8.9 2.2 7.5 5.1 2.0 1 1 1 2 2 2 0 TMPIT-like protein PUNUT PF16913.5 RLN91836.1 - 5.1e-06 25.9 10.9 8.2e-06 25.3 10.9 1.3 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 RLN91836.1 - 9.7e-05 22.6 24.3 0.022 14.9 4.9 3.4 3 0 0 3 3 3 3 EamA-like transporter family Nuc_sug_transp PF04142.15 RLN91836.1 - 0.0062 15.7 1.6 0.009 15.2 0.1 1.9 2 0 0 2 2 2 1 Nucleotide-sugar transporter TMEM234 PF10639.9 RLN91836.1 - 0.025 14.6 0.3 0.025 14.6 0.3 2.2 2 0 0 2 2 2 0 Putative transmembrane family 234 TPT PF03151.16 RLN91836.1 - 0.065 12.6 11.6 0.037 13.4 2.8 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family Cupin_2 PF07883.11 RLN91837.1 - 5e-10 38.9 0.9 0.00027 20.6 0.1 2.7 3 0 0 3 3 3 2 Cupin domain Cupin_1 PF00190.22 RLN91837.1 - 0.00033 20.3 0.4 0.03 14.0 0.0 2.3 2 0 0 2 2 2 2 Cupin CENP-C_C PF11699.8 RLN91837.1 - 0.008 16.4 0.4 0.028 14.6 0.1 2.0 2 1 0 2 2 2 1 Mif2/CENP-C like Cupin_3 PF05899.12 RLN91837.1 - 0.023 14.4 0.1 0.94 9.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF861) ARD PF03079.14 RLN91837.1 - 0.065 13.4 0.0 10 6.3 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family EutQ PF06249.12 RLN91837.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Arm PF00514.23 RLN91838.1 - 1.6e-14 53.3 53.9 0.015 15.3 0.1 17.6 18 1 0 19 19 19 5 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.14 RLN91838.1 - 0.025 13.8 0.2 0.025 13.8 0.2 4.4 5 0 0 5 5 5 0 V-ATPase subunit H Arm_2 PF04826.13 RLN91838.1 - 0.026 14.0 6.3 1.4 8.3 0.2 3.9 4 0 0 4 4 4 0 Armadillo-like KAP PF05804.12 RLN91838.1 - 0.68 8.0 6.9 0.23 9.6 0.3 3.2 4 0 0 4 4 4 0 Kinesin-associated protein (KAP) Vac14_Fab1_bd PF12755.7 RLN91838.1 - 2.5 8.8 4.4 47 4.7 0.0 4.4 4 1 1 5 5 5 0 Vacuolar 14 Fab1-binding region tRNA_anti_2 PF13742.6 RLN91839.1 - 0.00011 22.4 0.0 0.00015 21.9 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-codon PF01336.25 RLN91839.1 - 0.00043 20.2 0.0 0.00063 19.7 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RNase_HII PF01351.18 RLN91840.1 - 6.5e-38 130.6 0.0 8e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII HAUS2 PF15003.6 RLN91840.1 - 0.085 12.6 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 Myosin_head PF00063.21 RLN91841.1 - 1.4e-203 677.9 0.0 1.9e-203 677.4 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) FYVE PF01363.21 RLN91841.1 - 3.9e-12 46.1 11.2 1.1e-11 44.6 11.2 1.8 1 0 0 1 1 1 1 FYVE zinc finger IQ PF00612.27 RLN91841.1 - 0.057 13.2 0.3 0.057 13.2 0.3 6.2 5 0 0 5 5 5 0 IQ calmodulin-binding motif Myosin_N PF02736.19 RLN91841.1 - 0.083 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain TsaE PF02367.17 RLN91841.1 - 0.1 12.6 0.3 0.92 9.5 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 RLN91841.1 - 0.16 12.4 0.0 0.72 10.4 0.0 2.2 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 RLN91841.1 - 0.41 11.0 0.0 0.41 11.0 0.0 4.1 3 1 0 3 3 3 0 AAA ATPase domain zf-AN1 PF01428.16 RLN91841.1 - 1.7 8.8 11.8 5.1 7.4 11.8 1.8 1 0 0 1 1 1 0 AN1-like Zinc finger zf-UBP PF02148.19 RLN91841.1 - 8.2 6.8 8.9 30 5.1 8.9 2.0 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein HLH PF00010.26 RLN91843.1 - 3e-09 36.7 1.6 5.5e-09 35.9 1.6 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 RLN91843.1 - 0.0016 18.4 0.0 0.0041 17.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 RLN91843.1 - 0.0049 17.1 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 RLN91843.1 - 0.0056 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_5 PF07310.13 RLN91843.1 - 0.022 14.5 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 PAS domain PAS_3 PF08447.12 RLN91843.1 - 0.052 13.9 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 PAS fold Ribosomal_L20 PF00453.18 RLN91843.1 - 0.053 13.6 1.1 0.14 12.3 1.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L20 MRPL52 PF18699.1 RLN91843.1 - 0.072 13.3 0.2 0.072 13.3 0.2 2.7 1 1 1 2 2 2 0 Mitoribosomal protein mL52 Not3 PF04065.15 RLN91845.1 - 0.0069 15.8 0.5 0.01 15.3 0.5 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component T2SSM PF04612.12 RLN91845.1 - 0.84 9.7 3.4 1.3 9.0 3.4 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DUF2207 PF09972.9 RLN91846.1 - 0.036 12.9 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Romo1 PF10247.9 RLN91846.1 - 0.46 10.9 5.7 1.6 9.1 2.8 2.6 2 1 1 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Gpi1 PF05024.15 RLN91847.1 - 3.5e-45 154.4 3.5 5.3e-45 153.8 3.5 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Allexi_40kDa PF05549.11 RLN91848.1 - 0.017 14.6 2.5 0.034 13.7 2.5 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein Swi5 PF07061.11 RLN91848.1 - 0.19 11.8 9.4 3 8.0 0.0 3.9 3 0 0 3 3 3 0 Swi5 DUF1664 PF07889.12 RLN91848.1 - 2.3 8.3 10.5 3.6 7.7 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Nop14 PF04147.12 RLN91848.1 - 7.3 4.7 40.9 0.031 12.5 25.6 2.3 2 0 0 2 2 2 0 Nop14-like family TFIIA PF03153.13 RLN91848.1 - 9.8 6.0 41.2 1.3 9.0 5.8 3.2 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit HLH PF00010.26 RLN91849.1 - 2.7e-08 33.6 1.5 4.9e-08 32.8 1.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF812 PF05667.11 RLN91849.1 - 0.0082 15.1 1.7 0.013 14.5 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) COesterase PF00135.28 RLN91850.1 - 1e-23 84.1 1.1 5.2e-23 81.7 1.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family BLF1 PF17752.1 RLN91851.1 - 0.11 11.8 0.1 0.23 10.7 0.1 1.4 1 0 0 1 1 1 0 Burkholderia lethal factor 1 COesterase PF00135.28 RLN91852.1 - 1.7e-24 86.6 0.0 1.9e-24 86.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family fn3 PF00041.21 RLN91853.1 - 5.2e-45 151.7 26.6 8.4e-05 22.8 0.0 17.4 17 0 0 17 17 17 13 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RLN91853.1 - 2.4e-06 28.0 11.9 0.24 12.0 0.1 7.7 10 0 0 10 10 10 2 Purple acid Phosphatase, N-terminal domain LEA_2 PF03168.13 RLN91853.1 - 0.14 12.7 0.1 4.3 7.9 0.0 3.4 3 0 0 3 3 3 0 Late embryogenesis abundant protein Ank_2 PF12796.7 RLN91855.1 - 5.1e-28 97.5 0.1 2.7e-13 50.3 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN91855.1 - 1.1e-23 83.2 0.1 7.8e-10 39.1 0.0 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN91855.1 - 9.4e-23 77.8 0.5 1.2e-05 25.3 0.0 5.3 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 RLN91855.1 - 3.8e-21 74.5 0.9 7.1e-07 29.4 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 RLN91855.1 - 5.7e-18 64.8 0.2 9.3e-09 35.4 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Pkinase PF00069.25 RLN91855.1 - 4.7e-11 42.5 0.0 1.6e-10 40.8 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN91855.1 - 7.2e-09 35.3 1.4 1.3e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase WW PF00397.26 RLN91855.1 - 8.1e-06 25.8 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 WW domain Glyco_hyd_101C PF17451.2 RLN91855.1 - 0.054 13.8 0.0 0.19 12.0 0.0 1.9 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain PQQ PF01011.21 RLN91855.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat BCNT PF07572.12 RLN91856.1 - 3.1e-21 75.2 0.5 7e-21 74.1 0.5 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development TMEM234 PF10639.9 RLN91856.1 - 3.1e-05 24.0 0.0 5.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Putative transmembrane family 234 ABC2_membrane PF01061.24 RLN91857.1 - 1.1e-34 119.7 30.2 1.6e-34 119.2 30.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 RLN91857.1 - 2.6e-06 26.8 16.5 2.6e-06 26.8 16.5 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein PDR_CDR PF06422.12 RLN91857.1 - 8.9e-05 22.3 0.0 8.9e-05 22.3 0.0 3.2 3 2 2 5 5 5 1 CDR ABC transporter CLASP_N PF12348.8 RLN91858.1 - 3.7e-07 29.9 9.4 0.0024 17.5 0.1 4.3 5 0 0 5 5 5 2 CLASP N terminal HEAT PF02985.22 RLN91858.1 - 6.4e-05 22.9 12.8 15 6.2 0.2 8.7 9 0 0 9 9 9 2 HEAT repeat Ipi1_N PF12333.8 RLN91858.1 - 0.0081 16.7 0.1 0.33 11.6 0.0 3.2 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.6 RLN91858.1 - 0.0089 16.5 3.1 13 6.4 0.0 5.6 5 0 0 5 5 5 1 HEAT-like repeat Kisspeptin PF15152.6 RLN91858.1 - 0.019 15.7 0.4 0.088 13.6 0.1 2.3 2 0 0 2 2 2 0 Kisspeptin DUF4468 PF14730.6 RLN91858.1 - 0.023 15.0 0.2 0.052 13.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4468) with TBP-like fold CM_1 PF07736.11 RLN91858.1 - 0.049 14.0 0.1 1.4 9.4 0.1 2.7 2 0 0 2 2 2 0 Chorismate mutase type I DUF4508 PF14969.6 RLN91858.1 - 0.083 13.1 0.1 1.8 8.9 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) RTP1_C1 PF10363.9 RLN91858.1 - 0.49 10.6 3.3 22 5.2 0.0 3.6 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Hist_deacetyl PF00850.19 RLN91859.1 - 1.4e-75 254.7 0.6 2.1e-75 254.1 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylase domain GDNF PF02351.16 RLN91860.1 - 1.4 9.9 7.1 2.1 9.4 3.9 2.2 2 0 0 2 2 2 0 GDNF/GAS1 domain ADH_N PF08240.12 RLN91861.1 - 1.3e-32 112.0 0.3 2.7e-32 110.9 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN91861.1 - 4.1e-19 68.9 1.7 4.1e-19 68.9 1.7 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 RLN91861.1 - 0.00016 21.2 0.6 0.0003 20.3 0.2 1.6 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 RLN91861.1 - 0.0038 16.5 0.9 0.0053 16.1 0.9 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 RLN91861.1 - 0.059 14.1 0.1 0.12 13.1 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 RLN91861.1 - 0.12 13.1 0.0 0.27 11.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 RLN91861.1 - 0.15 11.7 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ank_2 PF12796.7 RLN91862.1 - 1.1e-09 38.7 0.4 3.7e-05 24.2 0.0 2.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN91862.1 - 2.8e-08 34.2 0.2 0.00012 22.5 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN91862.1 - 3.9e-08 33.4 0.7 5.5e-05 23.4 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN91862.1 - 5.8e-05 23.4 1.1 0.76 10.3 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 RLN91862.1 - 0.00025 21.3 0.4 2.8 8.8 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat DUF5631 PF18645.1 RLN91862.1 - 0.0052 17.1 0.0 0.014 15.8 0.0 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5631) DUF2013 PF09431.10 RLN91863.1 - 2e-12 47.4 0.1 3.4e-12 46.7 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2013) Pex26 PF07163.12 RLN91863.1 - 0.0011 18.4 0.7 0.0045 16.3 0.1 1.9 2 0 0 2 2 2 1 Pex26 protein DUF1993 PF09351.10 RLN91863.1 - 0.015 15.4 0.1 0.027 14.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) RPAP3_C PF13877.6 RLN91863.1 - 0.073 13.6 0.0 0.24 12.0 0.0 2.0 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 Rep_fac_C PF08542.11 RLN91863.1 - 0.12 12.8 0.0 0.34 11.4 0.0 1.7 1 0 0 1 1 1 0 Replication factor C C-terminal domain Adaptin_N PF01602.20 RLN91864.1 - 0.15 10.6 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 Adaptin N terminal region Peptidase_M6 PF05547.11 RLN91865.1 - 0.0011 17.4 1.8 0.0016 16.9 1.8 1.2 1 0 0 1 1 1 1 Immune inhibitor A peptidase M6 Reprolysin_4 PF13583.6 RLN91865.1 - 0.0076 15.9 1.4 0.0078 15.9 0.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 RLN91865.1 - 0.018 15.2 4.1 0.022 14.9 0.0 2.6 2 1 0 2 2 2 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 RLN91865.1 - 0.053 14.0 0.2 0.24 11.9 0.0 2.0 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like FSA_C PF10479.9 RLN91865.1 - 7.5 4.6 11.1 10 4.1 11.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Peptidase_M54 PF07998.11 RLN91866.1 - 3.2e-07 30.5 0.1 1e-06 28.9 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M54 Reprolysin_4 PF13583.6 RLN91866.1 - 0.097 12.3 0.4 0.17 11.5 0.4 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 RLN91866.1 - 0.14 12.7 0.2 0.29 11.7 0.2 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 RLN91866.1 - 0.2 10.6 0.1 0.33 9.9 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 ANAPC4 PF12896.7 RLN91866.1 - 0.21 11.1 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Peptidase_M57 PF12388.8 RLN91866.1 - 0.21 11.1 0.2 0.35 10.5 0.2 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_5 PF13688.6 RLN91866.1 - 1 9.5 3.0 2 8.5 1.4 1.9 1 1 1 2 2 2 0 Metallo-peptidase family M12 Peptidase_S24 PF00717.23 RLN91867.1 - 1.9e-07 30.9 0.0 2.6e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like ELMO_CED12 PF04727.13 RLN91868.1 - 4.3e-27 95.4 0.0 8.3e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family TRAPPC9-Trs120 PF08626.11 RLN91869.1 - 3.3e-34 117.6 0.0 9.4e-21 73.0 0.0 4.1 4 0 0 4 4 4 4 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF812 PF05667.11 RLN91870.1 - 0.01 14.7 5.3 0.011 14.6 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4988 PF16378.5 RLN91870.1 - 0.04 13.6 0.2 0.066 12.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function ATG16 PF08614.11 RLN91870.1 - 0.047 13.9 10.2 0.052 13.8 10.2 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CSRNP_N PF16019.5 RLN91870.1 - 0.054 13.4 6.5 0.067 13.1 6.5 1.0 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus 2_5_RNA_ligase2 PF13563.6 RLN91871.1 - 0.0078 16.1 15.8 0.024 14.6 3.1 3.3 3 2 1 4 4 4 2 2'-5' RNA ligase superfamily Arf PF00025.21 RLN91872.1 - 9.6e-18 64.2 0.0 6e-13 48.6 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_22 PF13401.6 RLN91872.1 - 0.0058 16.9 0.1 0.011 16.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 RLN91872.1 - 0.088 12.2 0.2 0.23 10.9 0.2 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 RLN91872.1 - 0.1 13.0 0.3 0.2 12.0 0.3 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 RLN91872.1 - 0.13 12.0 1.2 0.22 11.2 1.2 1.3 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 RLN91872.1 - 0.13 11.4 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 PIF1-like helicase Thymidylate_kin PF02223.17 RLN91872.1 - 0.16 11.6 0.0 0.35 10.5 0.0 1.5 2 0 0 2 2 2 0 Thymidylate kinase G-alpha PF00503.20 RLN91872.1 - 0.24 10.5 0.0 2.4 7.2 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit Aa_trans PF01490.18 RLN91873.1 - 1.4e-33 116.2 16.7 1.9e-33 115.8 16.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2374 PF09574.10 RLN91873.1 - 0.41 10.5 4.9 0.37 10.7 1.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) Dioxygenase_C PF00775.21 RLN91875.1 - 1.8e-08 34.0 0.1 3.2e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase CCDC92 PF14916.6 RLN91876.1 - 0.028 14.2 0.5 5.1 6.9 0.1 2.5 2 0 0 2 2 2 0 Coiled-coil domain of unknown function SnoaL_2 PF12680.7 RLN91876.1 - 0.041 14.5 0.0 0.088 13.5 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain DUF1843 PF08898.10 RLN91876.1 - 0.058 13.9 0.3 7.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) ABC_tran_CTD PF16326.5 RLN91876.1 - 0.069 13.4 0.4 0.41 10.9 0.1 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain bZIP_1 PF00170.21 RLN91876.1 - 0.92 9.7 12.8 0.12 12.5 7.7 2.2 3 1 0 3 3 3 0 bZIP transcription factor Atg14 PF10186.9 RLN91876.1 - 1.2 8.2 6.8 1.7 7.7 6.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fmp27_WPPW PF10359.9 RLN91876.1 - 4.2 6.1 7.0 5.6 5.7 7.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Ribosomal_S4e PF00900.20 RLN91877.1 - 9.5e-29 99.1 0.5 2.1e-28 98.0 0.5 1.6 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 RLN91877.1 - 3e-22 78.0 0.0 5.2e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus KOW PF00467.29 RLN91877.1 - 0.00033 20.5 4.1 0.00059 19.7 0.3 2.9 3 0 0 3 3 3 1 KOW motif RNA_pol_Rpb5_C PF01191.19 RLN91877.1 - 0.045 13.6 0.9 1.4 8.8 0.8 2.4 1 1 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain Sipho_tail PF05709.11 RLN91877.1 - 0.056 12.8 0.0 0.069 12.6 0.0 1.2 1 0 0 1 1 1 0 Phage tail protein Pro_isomerase PF00160.21 RLN91878.1 - 3.8e-34 118.3 0.0 4.3e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Piwi PF02171.17 RLN91881.1 - 0.00043 19.6 0.0 0.00061 19.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain MtN3_slv PF03083.16 RLN91882.1 - 1.1e-28 99.1 6.9 1.2e-20 73.4 0.5 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange 2HCT PF03390.15 RLN91882.1 - 0.0018 17.0 1.6 0.0031 16.2 1.6 1.3 1 0 0 1 1 1 1 2-hydroxycarboxylate transporter family DUF4763 PF15960.5 RLN91882.1 - 0.13 11.6 1.2 0.18 11.1 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DUF1129 PF06570.11 RLN91882.1 - 0.18 11.3 4.0 0.24 10.9 2.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) B12D PF06522.11 RLN91882.1 - 2.2 8.2 4.4 49 3.8 0.1 3.2 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit MARVEL PF01284.23 RLN91882.1 - 2.6 8.1 8.7 12 5.9 8.7 2.1 1 1 0 1 1 1 0 Membrane-associating domain Imp-YgjV PF10688.9 RLN91882.1 - 3 7.7 7.4 4.5 7.1 0.7 2.6 2 1 0 2 2 2 0 Bacterial inner membrane protein TGase_elicitor PF16683.5 RLN91883.1 - 4.6e-166 552.0 0.6 5.3e-166 551.8 0.6 1.0 1 0 0 1 1 1 1 Transglutaminase elicitor DDE_Tnp_ISL3 PF01610.17 RLN91884.1 - 0.011 15.5 0.3 0.024 14.4 0.2 1.5 1 1 0 1 1 1 0 Transposase MULE PF10551.9 RLN91884.1 - 0.018 15.5 0.0 0.049 14.0 0.0 1.8 1 0 0 1 1 1 0 MULE transposase domain Hist_deacetyl PF00850.19 RLN91885.1 - 0.0015 18.1 0.0 0.0039 16.7 0.0 1.6 1 0 0 1 1 1 1 Histone deacetylase domain CMS1 PF14617.6 RLN91885.1 - 0.83 8.9 6.1 0.58 9.4 2.4 2.4 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit PX PF00787.24 RLN91886.1 - 0.0026 17.7 0.4 0.0089 16.0 0.4 1.8 1 1 0 1 1 1 1 PX domain CCDC53 PF10152.9 RLN91886.1 - 2.4 8.5 6.8 5.1 7.5 6.8 1.6 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Ketoacyl-synt_C PF02801.22 RLN91887.1 - 2.5e-14 53.3 0.0 6.6e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 RLN91887.1 - 7.3e-14 51.9 0.0 1.5e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily ketoacyl-synt PF00109.26 RLN91887.1 - 8.1e-10 38.7 1.0 8.1e-10 38.7 1.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain cNMP_binding PF00027.29 RLN91888.1 - 4.1e-13 49.2 0.1 7.1e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain E2F_TDP PF02319.20 RLN91889.1 - 0.009 16.0 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain LRR_6 PF13516.6 RLN91890.1 - 7.3e-18 63.0 10.3 2.5e-05 24.0 0.2 5.5 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.7 RLN91890.1 - 0.0048 17.3 1.9 1.3 9.5 0.1 3.6 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) Neogenin_C PF06583.12 RLN91890.1 - 0.013 15.4 0.6 0.023 14.5 0.6 1.3 1 0 0 1 1 1 0 Neogenin C-terminus LRR_8 PF13855.6 RLN91890.1 - 0.57 10.0 2.3 4.8 7.0 0.1 2.9 2 1 1 3 3 3 0 Leucine rich repeat PhoLip_ATPase_C PF16212.5 RLN91892.1 - 6.3e-66 222.7 20.2 6.3e-66 222.7 20.2 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RLN91892.1 - 4.9e-25 87.0 1.3 1.5e-24 85.5 1.3 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 RLN91892.1 - 9.6e-11 41.6 0.0 5.7e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RLN91892.1 - 3.9e-10 40.4 0.5 0.00075 19.8 0.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RLN91892.1 - 6.8e-05 22.5 0.0 0.00021 20.9 0.0 1.8 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RLN91892.1 - 0.0016 18.2 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF659 PF04937.15 RLN91893.1 - 3.1e-06 27.1 0.0 5.7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 RLN91893.1 - 3.2e-05 23.7 0.1 7.3e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase_Tyr PF07714.17 RLN91895.1 - 8.4e-10 38.4 0.1 9e-10 38.3 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN91895.1 - 6.7e-08 32.2 0.0 8e-08 32.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain DUF4096 PF13340.6 RLN91895.1 - 0.14 12.4 0.1 0.21 11.8 0.1 1.3 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) Zip PF02535.22 RLN91896.1 - 1.4e-29 103.4 5.8 4e-29 101.9 5.7 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter Cu-oxidase_2 PF07731.14 RLN91896.1 - 2.9e-12 46.5 3.1 2.5e-11 43.4 3.1 2.4 1 1 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN91896.1 - 3.2e-10 40.0 2.7 1.5e-07 31.4 0.1 3.1 3 0 0 3 3 3 2 Multicopper oxidase GAF PF01590.26 RLN91897.1 - 1e-13 52.1 0.3 3.1e-07 31.1 0.0 3.8 4 0 0 4 4 4 2 GAF domain GAF_2 PF13185.6 RLN91897.1 - 8.5e-07 29.4 0.3 0.13 12.6 0.0 4.9 4 2 1 5 5 5 2 GAF domain GAF_3 PF13492.6 RLN91897.1 - 5e-06 26.9 0.2 0.18 12.2 0.0 4.0 4 0 0 4 4 4 3 GAF domain Peptidase_S15 PF02129.18 RLN91898.1 - 2.2e-33 116.0 1.4 6.2e-33 114.5 1.4 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 RLN91898.1 - 1.6e-17 64.2 0.1 3.1e-17 63.3 0.1 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 RLN91898.1 - 0.00013 21.3 0.2 0.00021 20.6 0.2 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EF-hand_6 PF13405.6 RLN91899.1 - 4.5e-15 54.2 0.2 0.0079 16.0 0.0 4.9 3 1 1 4 4 4 4 EF-hand domain LRR_6 PF13516.6 RLN91899.1 - 5.2e-15 54.2 15.1 0.0017 18.3 0.0 8.4 8 0 0 8 8 8 4 Leucine Rich repeat EF-hand_7 PF13499.6 RLN91899.1 - 6.9e-15 55.3 1.4 2.4e-06 27.9 0.1 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN91899.1 - 2.1e-14 51.9 0.0 0.012 15.1 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 RLN91899.1 - 3.4e-09 35.8 0.3 0.0035 16.8 0.0 4.3 4 0 0 4 4 4 2 EF hand DUF4476 PF14771.6 RLN91899.1 - 7e-08 32.7 0.1 8.1e-05 22.9 0.1 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4476) EF-hand_8 PF13833.6 RLN91899.1 - 3.3e-07 30.1 0.3 0.14 12.0 0.0 4.5 3 1 1 4 4 4 2 EF-hand domain pair LRR_4 PF12799.7 RLN91899.1 - 8.4e-05 22.9 0.3 1.3 9.5 0.0 3.9 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) Isochorismatase PF00857.20 RLN91899.1 - 0.00021 21.5 0.0 0.004 17.4 0.0 2.7 1 1 0 1 1 1 1 Isochorismatase family LRR_1 PF00560.33 RLN91899.1 - 0.014 15.8 0.1 1.7e+02 3.4 0.0 5.8 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 RLN91899.1 - 2.9 7.7 11.2 2 8.2 0.4 4.8 4 2 0 4 4 4 0 Leucine rich repeat ABC_membrane PF00664.23 RLN91900.1 - 9.3e-107 356.7 24.9 6.7e-54 183.4 4.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN91900.1 - 1e-42 145.9 0.3 3.1e-36 124.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 RLN91900.1 - 6.5e-07 29.4 0.0 0.0076 16.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 RLN91900.1 - 7.8e-06 25.6 0.4 0.086 12.6 0.1 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.19 RLN91900.1 - 1.1e-05 24.9 0.9 5.6e-05 22.7 0.1 2.1 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RLN91900.1 - 0.00013 22.3 1.7 0.031 14.5 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RLN91900.1 - 0.0013 18.3 0.0 1.6 8.2 0.0 2.8 3 0 0 3 3 3 2 P-loop containing dynein motor region ABC_ATPase PF09818.9 RLN91900.1 - 0.0014 17.5 0.4 0.011 14.6 0.2 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 RLN91900.1 - 0.0014 18.2 3.0 0.81 9.2 2.6 3.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN91900.1 - 0.0018 18.7 3.1 0.027 14.8 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 RLN91900.1 - 0.013 15.9 2.3 0.16 12.4 0.3 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 RLN91900.1 - 0.019 14.7 0.1 2.4 7.9 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_28 PF13521.6 RLN91900.1 - 0.024 14.9 2.3 0.46 10.7 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 RLN91900.1 - 0.027 14.6 0.4 16 5.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 RLN91900.1 - 0.057 13.2 1.2 0.5 10.1 0.2 2.4 2 1 0 2 2 2 0 DEAD/DEAH box helicase APS_kinase PF01583.20 RLN91900.1 - 0.088 12.7 0.5 2.1 8.2 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase MoaE PF02391.17 RLN91900.1 - 0.24 11.7 1.3 0.57 10.5 0.2 2.2 2 0 0 2 2 1 0 MoaE protein ABC_membrane PF00664.23 RLN91901.1 - 8.2e-103 343.8 23.7 2.1e-54 185.0 4.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN91901.1 - 3.5e-70 234.9 0.0 1.4e-33 116.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN91901.1 - 1.9e-13 50.4 1.9 1.3e-05 24.8 0.0 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 RLN91901.1 - 7.7e-08 32.4 0.0 0.0066 16.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 RLN91901.1 - 4e-06 25.9 3.3 0.036 12.9 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 RLN91901.1 - 4.3e-06 26.4 0.2 0.13 12.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN91901.1 - 8.4e-06 26.1 0.7 0.2 12.0 0.0 3.4 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 RLN91901.1 - 0.00042 20.5 3.4 0.64 10.3 0.6 4.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.20 RLN91901.1 - 0.0025 17.7 0.5 1.6 8.6 0.1 3.1 4 0 0 4 4 3 1 Adenylylsulphate kinase AAA_25 PF13481.6 RLN91901.1 - 0.0031 17.1 0.4 24 4.4 0.0 3.7 4 0 0 4 4 4 0 AAA domain IstB_IS21 PF01695.17 RLN91901.1 - 0.0063 16.3 0.4 2.2 8.0 0.0 3.5 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_28 PF13521.6 RLN91901.1 - 0.0092 16.2 0.1 5.3 7.3 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RLN91901.1 - 0.0097 15.4 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region G-alpha PF00503.20 RLN91901.1 - 0.018 14.2 0.0 5.2 6.1 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_23 PF13476.6 RLN91901.1 - 0.031 14.8 2.3 0.65 10.5 0.1 2.8 3 0 0 3 3 2 0 AAA domain AAA_15 PF13175.6 RLN91901.1 - 0.046 13.4 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 RLN91901.1 - 0.067 12.5 0.0 0.71 9.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 RLN91901.1 - 0.078 13.5 0.0 8.9 6.9 0.0 3.0 2 0 0 2 2 2 0 AAA domain MoaE PF02391.17 RLN91901.1 - 0.42 10.9 3.8 17 5.7 0.1 3.0 3 0 0 3 3 3 0 MoaE protein ABC_tran PF00005.27 RLN91902.1 - 4.7e-28 98.4 0.0 7.6e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN91902.1 - 2.4e-06 27.1 0.1 3.6e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 RLN91902.1 - 0.0013 17.6 0.0 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class SbcCD_C PF13558.6 RLN91902.1 - 0.0015 18.8 1.0 0.058 13.6 1.0 2.5 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit PBCV_basic_adap PF08789.10 RLN91904.1 - 2.1 8.5 7.9 0.071 13.2 1.4 2.0 2 0 0 2 2 2 0 PBCV-specific basic adaptor domain UPF1_Zn_bind PF09416.10 RLN91905.1 - 1.4e-73 245.9 0.9 1.4e-73 245.9 0.9 2.0 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 RLN91905.1 - 1.4e-59 201.1 0.0 2.4e-59 200.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RLN91905.1 - 2.7e-49 168.3 2.4 2.5e-30 106.1 0.2 2.2 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 RLN91905.1 - 5.4e-27 93.9 0.0 1.3e-26 92.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 RLN91905.1 - 9.8e-14 51.5 0.6 8.1e-13 48.5 0.6 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RLN91905.1 - 5.4e-10 39.8 0.3 1.3e-09 38.5 0.3 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 RLN91905.1 - 0.00038 20.5 0.0 0.00066 19.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 RLN91905.1 - 0.00044 19.6 2.9 0.0076 15.5 0.3 3.4 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 RLN91905.1 - 0.0007 19.5 0.3 0.002 18.0 0.3 1.9 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 RLN91905.1 - 0.0016 18.0 0.1 0.64 9.5 0.1 2.5 1 1 0 2 2 2 2 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 RLN91905.1 - 0.0054 15.9 0.1 2.3 7.3 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_25 PF13481.6 RLN91905.1 - 0.0083 15.7 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 RLN91905.1 - 0.049 13.1 0.1 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 RLN91905.1 - 0.075 12.4 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA PF00004.29 RLN91905.1 - 0.082 13.3 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN91905.1 - 0.11 12.9 0.1 0.27 11.6 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain HCMV_UL139 PF12507.8 RLN91905.1 - 0.14 12.6 0.3 0.28 11.5 0.3 1.4 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein Ribosomal_S13_N PF08069.12 RLN91905.1 - 0.16 12.0 0.0 0.53 10.4 0.0 1.9 2 0 0 2 2 1 0 Ribosomal S13/S15 N-terminal domain PDZ_6 PF17820.1 RLN91906.1 - 5.8e-09 35.7 0.0 0.00048 19.9 0.0 3.0 3 0 0 3 3 3 2 PDZ domain PknG_rubred PF16919.5 RLN91906.1 - 0.0006 20.0 0.3 0.0057 16.8 0.0 2.7 2 0 0 2 2 2 1 Protein kinase G rubredoxin domain PDZ PF00595.24 RLN91906.1 - 0.0019 18.5 0.0 1.4 9.4 0.0 2.6 2 0 0 2 2 2 2 PDZ domain OrfB_Zn_ribbon PF07282.11 RLN91906.1 - 0.2 11.6 0.1 0.51 10.3 0.1 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-RRN7 PF11781.8 RLN91906.1 - 5 6.9 5.6 16 5.3 5.6 1.8 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Axin_b-cat_bind PF08833.10 RLN91906.1 - 9.4 6.4 6.2 45 4.3 0.1 3.5 3 0 0 3 3 3 0 Axin beta-catenin binding domain ubiquitin PF00240.23 RLN91907.1 - 1.3e-15 56.9 1.2 3.8e-15 55.4 1.2 1.6 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RLN91907.1 - 9e-07 28.6 0.1 6.6e-06 25.9 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 RLN91907.1 - 0.00051 20.5 0.1 0.00062 20.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 RLN91907.1 - 0.011 16.0 0.1 0.018 15.4 0.1 1.4 1 1 0 1 1 1 0 Ubiquitin-like domain ChitinaseA_N PF08329.10 RLN91907.1 - 0.074 12.7 0.0 0.076 12.7 0.0 1.0 1 0 0 1 1 1 0 Chitinase A, N-terminal domain Ribosomal_S5_C PF03719.15 RLN91908.1 - 1.3e-23 82.2 0.0 1.6e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Tim17 PF02466.19 RLN91909.1 - 4.2e-13 49.6 8.8 7e-13 48.9 8.8 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Band_7 PF01145.25 RLN91909.1 - 8.3e-11 42.2 2.5 1.6e-10 41.3 2.5 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Glyco_transf_20 PF00982.21 RLN91911.1 - 5.8e-115 384.7 0.0 9.1e-115 384.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 RLN91911.1 - 4.9e-33 114.2 0.0 2.2e-32 112.0 0.0 2.2 2 1 0 2 2 2 1 Trehalose-phosphatase FWWh PF14922.6 RLN91913.1 - 7.7e-36 123.2 0.3 1.3e-35 122.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function WW PF00397.26 RLN91914.1 - 0.0041 17.2 0.1 0.0089 16.1 0.1 1.6 1 0 0 1 1 1 1 WW domain DUF594 PF04578.13 RLN91914.1 - 0.01 15.4 0.4 0.071 12.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF594 FAM176 PF14851.6 RLN91914.1 - 0.011 15.4 0.5 0.022 14.4 0.5 1.5 1 0 0 1 1 1 0 FAM176 family SDA1 PF05285.12 RLN91914.1 - 0.063 12.7 7.7 0.09 12.2 7.7 1.1 1 0 0 1 1 1 0 SDA1 Nop53 PF07767.11 RLN91914.1 - 0.071 12.5 9.5 0.11 11.9 9.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 RLN91914.1 - 0.095 11.0 12.6 0.14 10.5 12.6 1.1 1 0 0 1 1 1 0 CDC45-like protein B2-adapt-app_C PF09066.10 RLN91914.1 - 0.18 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain Sigma70_ner PF04546.13 RLN91914.1 - 0.35 10.7 4.6 0.56 10.1 4.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2231 PF09990.9 RLN91914.1 - 0.98 9.9 7.3 0.12 12.9 0.9 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) DNA_pol_phi PF04931.13 RLN91914.1 - 1.1 7.2 13.0 1.6 6.7 13.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi SPW PF03779.14 RLN91914.1 - 2.6 7.7 8.2 0.9 9.2 4.1 2.3 2 0 0 2 2 2 0 SPW repeat rRNA_processing PF08524.11 RLN91914.1 - 5.2 7.1 7.8 7.9 6.5 7.8 1.2 1 0 0 1 1 1 0 rRNA processing Mpp10 PF04006.12 RLN91914.1 - 8.5 4.7 12.8 12 4.2 12.8 1.1 1 0 0 1 1 1 0 Mpp10 protein UQ_con PF00179.26 RLN91915.1 - 7.6e-34 116.4 0.0 1.2e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UCH PF00443.29 RLN91917.1 - 4.6e-74 249.2 0.0 7.5e-74 248.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PX PF00787.24 RLN91917.1 - 1.7e-18 66.6 0.4 4.7e-18 65.2 0.4 1.7 1 0 0 1 1 1 1 PX domain UCH_1 PF13423.6 RLN91917.1 - 1.2e-15 57.9 0.2 6.9e-08 32.4 0.1 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 RLN91917.1 - 4.6e-14 52.8 0.0 1e-13 51.7 0.0 1.6 1 0 0 1 1 1 1 DUSP domain Raftlin PF15250.6 RLN91917.1 - 3.1 6.4 10.0 9.5 4.8 9.4 2.0 2 0 0 2 2 2 0 Raftlin DUF659 PF04937.15 RLN91918.1 - 1.3e-29 103.0 0.0 2.2e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 RLN91918.1 - 1.8e-12 46.9 0.5 1.1e-11 44.4 0.1 2.2 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region NAM-associated PF14303.6 RLN91919.1 - 1.6e-06 28.9 0.2 1.6e-06 28.9 0.2 2.2 2 1 1 3 3 3 1 No apical meristem-associated C-terminal domain GTP_EFTU PF00009.27 RLN91920.1 - 3.3e-37 127.9 0.0 5.6e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 RLN91920.1 - 4.5e-20 72.0 0.0 1.1e-19 70.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 RLN91920.1 - 2.3e-06 27.7 0.0 0.0015 18.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase HBS1_N PF08938.10 RLN91920.1 - 8.5e-05 22.8 0.0 0.00017 21.8 0.0 1.6 1 0 0 1 1 1 1 HBS1 N-terminus Glutaredoxin PF00462.24 RLN91921.1 - 1.9e-28 98.5 0.0 1.2e-17 63.8 0.0 2.3 2 0 0 2 2 2 2 Glutaredoxin SH3BGR PF04908.15 RLN91921.1 - 0.0026 17.9 0.0 0.29 11.3 0.0 2.6 2 1 0 2 2 2 1 SH3-binding, glutamic acid-rich protein ZinT PF09223.11 RLN91921.1 - 0.0064 16.4 0.0 1.9 8.4 0.0 2.5 2 1 1 3 3 3 2 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment ERM PF00769.19 RLN91921.1 - 0.07 12.9 0.3 10 5.8 0.0 2.7 3 0 0 3 3 3 0 Ezrin/radixin/moesin family GST_N_3 PF13417.6 RLN91921.1 - 0.12 12.9 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF2535 PF10751.9 RLN91921.1 - 0.14 12.7 0.4 33 5.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2535) PDZ_6 PF17820.1 RLN91922.1 - 0.0084 15.9 0.0 0.025 14.4 0.0 1.9 1 0 0 1 1 1 1 PDZ domain Trans_reg_C PF00486.28 RLN91923.1 - 0.16 12.1 0.9 34 4.6 0.0 3.4 3 1 1 4 4 4 0 Transcriptional regulatory protein, C terminal CENP-B_N PF04218.13 RLN91924.1 - 3e-12 46.0 0.9 4.7e-12 45.4 0.9 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc5 PF03221.16 RLN91924.1 - 7.1e-08 32.4 0.1 1.2e-07 31.7 0.1 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.6 RLN91924.1 - 8.8e-06 25.4 0.2 0.00031 20.4 0.1 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 RLN91924.1 - 0.00018 21.5 0.1 0.00037 20.5 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 RLN91924.1 - 0.00084 19.4 0.0 0.016 15.3 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 RLN91924.1 - 0.01 15.8 0.0 0.033 14.2 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn helix BrkDBD PF09607.10 RLN91924.1 - 0.05 13.4 0.2 0.32 10.8 0.1 2.2 2 0 0 2 2 2 0 Brinker DNA-binding domain HTH_3 PF01381.22 RLN91924.1 - 0.25 11.4 1.5 4.6 7.4 0.0 2.9 3 1 1 4 4 4 0 Helix-turn-helix Ank_2 PF12796.7 RLN91925.1 - 6.4e-38 129.2 8.4 3.8e-09 37.0 0.0 6.8 3 3 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN91925.1 - 3.5e-36 122.8 22.6 0.00012 22.3 0.1 14.6 4 3 11 16 16 16 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN91925.1 - 7.7e-32 109.3 14.2 5.4e-05 23.7 0.0 9.5 6 3 3 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN91925.1 - 6.6e-23 78.3 5.0 3 8.7 0.0 13.6 13 2 2 15 15 15 6 Ankyrin repeat DUF5049 PF16468.5 RLN91925.1 - 1.9e-07 30.9 0.5 24 4.9 0.1 8.0 6 2 4 10 10 10 0 Domain of unknown function (DUF5049) Ank PF00023.30 RLN91925.1 - 4.1e-07 30.2 2.9 17 6.1 0.0 9.4 6 2 2 8 8 8 1 Ankyrin repeat Helicase_PWI PF18149.1 RLN91925.1 - 0.031 14.4 0.1 1.3 9.3 0.1 3.5 2 1 2 4 4 4 0 N-terminal helicase PWI domain DUF1987 PF09345.10 RLN91925.1 - 7.2 6.3 7.1 21 4.8 0.1 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF1987) AAA_25 PF13481.6 RLN91926.1 - 0.0021 17.6 0.0 0.0043 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.7 RLN91926.1 - 0.035 13.0 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Y_phosphatase PF00102.27 RLN91926.1 - 0.078 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Fer2 PF00111.27 RLN91927.1 - 7.3e-13 48.3 1.5 9.4e-13 47.9 1.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain MCR PF18509.1 RLN91927.1 - 0.052 13.1 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 Magnetochrome domain VPS9 PF02204.18 RLN91928.1 - 7e-10 39.1 0.1 2.2e-09 37.5 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain LIM_bind PF01803.16 RLN91928.1 - 0.016 14.8 0.6 0.032 13.7 0.6 1.5 1 0 0 1 1 1 0 LIM-domain binding protein Oxysterol_BP PF01237.18 RLN91928.1 - 0.022 13.6 0.0 0.046 12.5 0.0 1.4 1 0 0 1 1 1 0 Oxysterol-binding protein Ras PF00071.22 RLN91929.1 - 1.2e-28 99.8 0.1 1.1e-15 57.6 0.0 2.3 1 1 1 2 2 2 2 Ras family KHA PF11834.8 RLN91929.1 - 1.2e-13 51.0 0.0 2.6e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel SAP PF02037.27 RLN91929.1 - 3.2e-11 42.7 1.9 7.4e-11 41.5 1.9 1.7 1 0 0 1 1 1 1 SAP domain Roc PF08477.13 RLN91929.1 - 6.5e-07 29.6 0.0 2.1e-06 27.9 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Telomere_Sde2_2 PF13297.6 RLN91929.1 - 0.11 12.1 0.9 18 5.1 0.0 2.7 2 0 0 2 2 2 0 Telomere stability C-terminal Pkinase PF00069.25 RLN91930.1 - 3.7e-48 164.2 0.0 4.7e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN91930.1 - 2.9e-43 148.0 0.0 3.7e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN91930.1 - 0.005 15.7 0.0 0.0072 15.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase PX PF00787.24 RLN91931.1 - 0.00092 19.2 0.1 0.0017 18.3 0.1 1.5 1 0 0 1 1 1 1 PX domain LZ_Tnp_IS66 PF13007.7 RLN91931.1 - 0.096 13.5 2.6 0.42 11.4 2.5 2.2 1 1 0 1 1 1 0 Transposase C of IS166 homeodomain GAF PF01590.26 RLN91932.1 - 0.026 15.2 0.0 0.037 14.6 0.0 1.3 1 0 0 1 1 1 0 GAF domain Hexapep PF00132.24 RLN91933.1 - 1.1e-12 47.2 11.6 4.9e-08 32.4 4.1 3.3 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 RLN91933.1 - 2.6e-12 46.8 0.1 4.3e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 RLN91933.1 - 8.2e-10 38.3 15.3 3.7e-07 29.8 4.8 4.1 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase Glyco_hydro_31 PF01055.26 RLN91935.1 - 1.1e-136 456.6 2.1 1.4e-136 456.2 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 RLN91935.1 - 4.9e-19 68.4 0.3 2e-18 66.5 0.0 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like Ras PF00071.22 RLN91936.1 - 2.3e-52 176.8 0.0 2.9e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN91936.1 - 5.3e-32 110.6 0.0 7.7e-32 110.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN91936.1 - 1.3e-10 41.1 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RLN91936.1 - 0.00014 21.3 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 RLN91936.1 - 0.0013 18.2 0.0 0.0041 16.6 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 RLN91936.1 - 0.026 14.0 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RLN91936.1 - 0.063 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 RLN91936.1 - 0.11 12.9 1.0 0.37 11.1 1.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 RLN91936.1 - 0.19 11.8 0.1 0.57 10.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain Vezatin PF12632.7 RLN91937.1 - 1.5e-06 27.8 0.4 3.2e-06 26.8 0.1 1.7 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes Pkinase PF00069.25 RLN91938.1 - 9.3e-52 176.0 0.0 1.1e-51 175.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN91938.1 - 5.6e-46 156.9 0.0 6.7e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RLN91938.1 - 0.03 13.3 0.1 0.18 10.7 0.1 1.9 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 RLN91938.1 - 0.12 11.1 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 RLN91939.1 - 2.9e-50 171.1 0.0 4.3e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN91939.1 - 1.3e-43 149.1 0.0 1.8e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase VSP PF03302.13 RLN91939.1 - 0.00016 20.7 1.9 0.00027 19.9 1.9 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein Kdo PF06293.14 RLN91939.1 - 0.16 11.3 0.1 0.28 10.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YabA PF06156.13 RLN91940.1 - 0.029 15.0 2.3 0.34 11.6 0.0 3.1 3 1 0 3 3 3 0 Initiation control protein YabA Golgin_A5 PF09787.9 RLN91940.1 - 0.2 11.1 14.4 0.071 12.6 4.0 2.8 2 1 0 2 2 2 0 Golgin subfamily A member 5 DivIC PF04977.15 RLN91940.1 - 2 8.3 12.2 3.3 7.6 0.2 4.2 4 0 0 4 4 4 0 Septum formation initiator Spc7 PF08317.11 RLN91940.1 - 7.1 5.4 14.6 5.3 5.8 1.7 2.8 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF1077 PF06417.12 RLN91942.1 - 5.2e-34 116.8 5.3 8.5e-34 116.1 5.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DDE_3 PF13358.6 RLN91943.1 - 0.017 14.9 0.0 0.29 10.9 0.0 2.1 1 1 0 1 1 1 0 DDE superfamily endonuclease DUF4471 PF14740.6 RLN91943.1 - 0.017 14.3 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) IF4E PF01652.18 RLN91944.1 - 6.4e-24 84.6 0.0 8.3e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Trehalase PF01204.18 RLN91945.1 - 1e-137 460.1 0.1 1.2e-137 459.9 0.1 1.0 1 0 0 1 1 1 1 Trehalase Glyco_hydro_63 PF03200.16 RLN91945.1 - 0.00014 20.8 2.0 0.035 12.9 0.1 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain TFIIS_M PF07500.14 RLN91946.1 - 1.8e-19 70.2 0.5 4.4e-19 69.0 0.5 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 RLN91946.1 - 4.1e-17 61.8 4.3 6.8e-17 61.0 4.3 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 RLN91946.1 - 1.1e-12 47.7 1.1 1.1e-12 47.7 1.1 2.9 3 0 0 3 3 3 1 TFIIS helical bundle-like domain zf-DNL PF05180.12 RLN91946.1 - 0.011 15.7 1.8 0.026 14.5 1.8 1.6 1 0 0 1 1 1 0 DNL zinc finger PHD_2 PF13831.6 RLN91947.1 - 1.4e-08 34.1 6.1 1.4e-08 34.1 6.1 2.4 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 RLN91947.1 - 3.3e-05 23.7 10.2 9.4e-05 22.2 10.2 1.8 1 0 0 1 1 1 1 PHD-finger WHIM1 PF15612.6 RLN91947.1 - 0.0034 16.9 0.1 0.0097 15.4 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 C1_1 PF00130.22 RLN91947.1 - 0.021 14.7 8.9 0.053 13.4 5.3 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 RLN91947.1 - 0.093 12.4 9.6 0.1 12.2 3.9 2.7 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_2 PF03107.16 RLN91947.1 - 0.8 10.1 8.9 2.6 8.4 5.5 2.5 2 0 0 2 2 2 0 C1 domain SLC12 PF03522.15 RLN91947.1 - 8.3 5.3 6.6 14 4.5 6.6 1.3 1 0 0 1 1 1 0 Solute carrier family 12 UCH PF00443.29 RLN91948.1 - 2.6e-17 63.2 0.1 4.1e-17 62.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 RLN91948.1 - 1.1e-11 44.3 0.1 3.3e-11 42.9 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain UCH_1 PF13423.6 RLN91948.1 - 7.7e-06 25.7 2.1 5.5e-05 22.9 2.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PH PF00169.29 RLN91948.1 - 0.01 16.4 0.0 0.025 15.1 0.0 1.7 1 0 0 1 1 1 0 PH domain UBA_4 PF14555.6 RLN91948.1 - 0.022 14.6 0.1 0.05 13.4 0.1 1.6 1 0 0 1 1 1 0 UBA-like domain PDZ_6 PF17820.1 RLN91948.1 - 0.042 13.7 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 PDZ domain EGF_2 PF07974.13 RLN91949.1 - 0.00034 20.9 13.3 0.00034 20.9 13.3 4.9 6 1 0 6 6 6 3 EGF-like domain EGF PF00008.27 RLN91949.1 - 0.0031 17.8 2.2 0.0031 17.8 2.2 4.3 4 0 0 4 4 4 3 EGF-like domain Complex1_51K PF01512.17 RLN91950.1 - 2e-47 160.8 0.0 1.9e-46 157.7 0.0 1.9 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit SLBB PF10531.9 RLN91950.1 - 0.022 14.6 0.0 0.066 13.1 0.0 1.9 1 0 0 1 1 1 0 SLBB domain DEAD PF00270.29 RLN91951.1 - 7.9e-49 165.8 0.0 1.7e-48 164.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN91951.1 - 8.8e-25 87.2 0.0 1.1e-23 83.7 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain GUCT PF08152.12 RLN91951.1 - 7.9e-23 80.6 0.0 2.1e-22 79.2 0.0 1.8 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.15 RLN91951.1 - 6.5e-07 29.5 2.1 1.3e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 RLN91951.1 - 0.26 10.6 12.8 2.2 7.5 0.0 2.5 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit TFIIF_alpha PF05793.12 RLN91951.1 - 0.39 9.3 24.7 0.62 8.6 24.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DDHD PF02862.17 RLN91951.1 - 0.91 9.6 3.1 1.9 8.6 3.1 1.5 1 0 0 1 1 1 0 DDHD domain DUF755 PF05501.11 RLN91951.1 - 1.4 9.2 16.0 3.3 8.0 16.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Ank_2 PF12796.7 RLN91952.1 - 8.6e-34 116.0 7.7 8.8e-08 32.6 0.0 6.7 3 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN91952.1 - 4.7e-31 106.8 14.9 0.00012 22.5 0.0 10.5 8 2 0 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN91952.1 - 1.2e-30 105.2 22.7 0.0047 17.2 0.3 13.6 4 2 10 14 14 14 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN91952.1 - 2.8e-20 70.2 6.6 0.65 10.7 0.1 14.0 12 2 3 15 15 15 3 Ankyrin repeat Ank PF00023.30 RLN91952.1 - 2.3e-05 24.7 1.0 12 6.6 0.0 7.8 4 3 0 4 4 4 1 Ankyrin repeat DUF5049 PF16468.5 RLN91952.1 - 7.2e-05 22.6 0.0 10 6.1 0.0 5.3 5 1 1 6 6 6 1 Domain of unknown function (DUF5049) Helicase_PWI PF18149.1 RLN91952.1 - 0.027 14.7 0.1 3.1 8.0 0.0 3.4 2 2 1 3 3 3 0 N-terminal helicase PWI domain Daxx PF03344.15 RLN91952.1 - 0.13 12.3 0.0 1.2e+02 2.9 0.0 4.5 5 2 2 7 7 7 0 Daxx N-terminal Rassf1C-interacting domain MIF PF01187.18 RLN91953.1 - 2e-08 34.5 0.2 0.00012 22.3 0.2 2.0 1 1 1 2 2 2 2 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 RLN91953.1 - 5.4e-06 26.2 0.0 0.00042 20.2 0.0 2.2 2 0 0 2 2 2 1 Tautomerase enzyme Tautomerase_2 PF14552.6 RLN91953.1 - 0.00068 19.7 0.0 0.00084 19.4 0.0 1.2 1 0 0 1 1 1 1 Tautomerase enzyme PIF6 PF05341.11 RLN91953.1 - 0.07 13.3 0.1 0.11 12.6 0.1 1.3 1 1 0 1 1 1 0 Per os infectivity factor 6 KorB PF08535.10 RLN91953.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 KorB domain MIF PF01187.18 RLN91954.1 - 9.4e-25 87.1 0.0 1.1e-24 87.0 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 RLN91954.1 - 2.4e-07 30.6 0.0 7.8e-07 28.9 0.0 1.8 2 1 0 2 2 2 1 Tautomerase enzyme Helicase_PWI PF18149.1 RLN91955.1 - 3.5e-39 133.4 2.8 1.1e-38 131.8 0.8 2.5 2 0 0 2 2 2 1 N-terminal helicase PWI domain PI3K_1B_p101 PF10486.9 RLN91955.1 - 0.52 8.0 5.3 0.92 7.2 5.3 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF659 PF04937.15 RLN91956.1 - 2.2e-20 73.0 1.0 6.2e-20 71.6 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 RLN91956.1 - 5.6e-10 38.9 0.1 1.4e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CLPTM1 PF05602.12 RLN91960.1 - 8.9e-33 113.9 0.0 1e-32 113.7 0.0 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PDZ_6 PF17820.1 RLN91961.1 - 1.7e-15 56.6 0.0 0.00042 20.1 0.0 3.8 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 RLN91961.1 - 3.3e-11 43.4 0.0 4.1e-05 23.8 0.0 3.6 3 0 0 3 3 3 3 PDZ domain PknG_rubred PF16919.5 RLN91961.1 - 0.00075 19.7 0.3 0.0079 16.4 0.0 2.9 2 0 0 2 2 2 1 Protein kinase G rubredoxin domain RasGAP_C PF03836.15 RLN91961.1 - 0.14 12.3 2.4 2.8 8.1 0.0 2.6 2 0 0 2 2 2 0 RasGAP C-terminus zf-RRN7 PF11781.8 RLN91961.1 - 5.5 6.8 5.4 16 5.3 5.4 1.8 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 2OG-FeII_Oxy_3 PF13640.6 RLN91962.1 - 1.4e-13 51.5 0.0 3.8e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Lectin_leg-like PF03388.13 RLN91963.1 - 1.2e-35 122.9 0.6 1.9e-35 122.3 0.6 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 RLN91963.1 - 1e-09 38.7 1.5 2.2e-09 37.6 1.5 1.5 1 1 0 1 1 1 1 Bacterial lectin MIS13 PF08202.11 RLN91963.1 - 0.00026 20.4 2.4 0.0004 19.8 2.4 1.2 1 0 0 1 1 1 1 Mis12-Mtw1 protein family CemA PF03040.14 RLN91963.1 - 0.16 11.8 1.6 0.25 11.3 1.6 1.2 1 0 0 1 1 1 0 CemA family Stathmin PF00836.19 RLN91963.1 - 0.29 11.1 6.9 0.5 10.3 6.9 1.3 1 0 0 1 1 1 0 Stathmin family Lectin_leg-like PF03388.13 RLN91964.1 - 1.1e-35 123.1 0.2 1.6e-35 122.6 0.2 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 RLN91964.1 - 4e-09 36.8 0.2 7.5e-09 35.9 0.2 1.4 1 1 0 1 1 1 1 Bacterial lectin ApoLp-III PF07464.11 RLN91964.1 - 0.0016 18.6 2.5 0.0028 17.8 2.5 1.3 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) DCB PF16213.5 RLN91964.1 - 0.036 13.7 0.8 0.063 12.9 0.8 1.3 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Nbl1_Borealin_N PF10444.9 RLN91964.1 - 0.11 12.2 0.4 0.11 12.2 0.4 1.9 1 1 1 2 2 2 0 Nbl1 / Borealin N terminal TRAF_BIRC3_bd PF16673.5 RLN91964.1 - 0.14 12.0 3.9 0.69 9.7 2.4 2.3 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain CcmH PF03918.14 RLN91964.1 - 1.2 8.4 2.9 8.3 5.7 0.7 2.6 3 0 0 3 3 3 0 Cytochrome C biogenesis protein Aha1_N PF09229.11 RLN91965.1 - 3.8e-20 72.5 0.0 7.9e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal TPR_1 PF00515.28 RLN91965.1 - 2.4e-09 36.6 6.1 0.00013 21.7 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN91965.1 - 4.6e-07 29.5 11.2 0.002 18.1 0.3 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN91965.1 - 0.00017 22.1 2.0 0.39 11.6 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN91965.1 - 0.00024 21.1 3.9 0.2 12.0 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN91965.1 - 0.00056 20.5 13.2 0.0055 17.3 0.4 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN91965.1 - 0.0007 19.2 1.2 0.018 14.7 0.1 2.7 2 1 1 3 3 3 1 TPR repeat TPR_19 PF14559.6 RLN91965.1 - 0.0065 17.0 9.5 0.013 16.0 2.5 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4850 PF16142.5 RLN91965.1 - 0.06 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4850) Fis1_TPR_C PF14853.6 RLN91965.1 - 0.075 13.1 0.7 0.16 12.1 0.7 1.5 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat UFC1 PF08694.11 RLN91965.1 - 0.08 12.6 0.0 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 TPR_9 PF13371.6 RLN91965.1 - 0.18 11.9 1.7 1.6 8.9 0.4 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN91965.1 - 0.65 10.3 7.3 5.7 7.3 3.0 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN91965.1 - 1.4 9.2 5.8 5.6 7.3 5.6 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 RLN91965.1 - 3.7 7.5 5.2 7.9 6.5 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat G-patch PF01585.23 RLN91966.1 - 1.1e-13 50.8 2.2 2.5e-13 49.7 0.9 2.2 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 RLN91966.1 - 2.7e-08 33.8 0.4 2.7e-08 33.8 0.4 2.5 2 0 0 2 2 2 1 G-patch domain SR-25 PF10500.9 RLN91966.1 - 0.0061 16.2 19.3 0.0061 16.2 19.3 2.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 RLN91966.1 - 0.029 12.7 7.9 0.032 12.5 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Coilin_N PF15862.5 RLN91966.1 - 0.031 14.1 9.6 0.044 13.6 9.6 1.3 1 0 0 1 1 1 0 Coilin N-terminus RR_TM4-6 PF06459.12 RLN91966.1 - 0.082 12.7 8.8 0.1 12.4 8.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 RLN91966.1 - 0.085 13.0 4.6 0.11 12.7 4.6 1.2 1 0 0 1 1 1 0 DDHD domain DUF3807 PF12720.7 RLN91966.1 - 0.11 12.8 12.7 0.15 12.3 12.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Glypican PF01153.19 RLN91966.1 - 0.14 11.0 4.1 0.17 10.7 4.1 1.1 1 0 0 1 1 1 0 Glypican Peptidase_S49_N PF08496.10 RLN91966.1 - 0.35 10.9 7.3 0.51 10.4 7.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Dsh_C PF12316.8 RLN91966.1 - 0.36 11.2 10.4 0.65 10.4 10.4 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal RNA_pol_Rpc4 PF05132.14 RLN91966.1 - 0.67 10.4 8.2 0.95 9.9 8.2 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 CCDC106 PF15794.5 RLN91966.1 - 1.1 9.0 14.0 1.5 8.5 14.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Presenilin PF01080.17 RLN91966.1 - 1.3 7.7 4.9 1.5 7.5 4.9 1.1 1 0 0 1 1 1 0 Presenilin Vfa1 PF08432.10 RLN91966.1 - 1.6 9.1 15.4 2.2 8.6 15.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4614 PF15391.6 RLN91966.1 - 1.7 8.6 9.2 2.9 7.9 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) RNA_polI_A34 PF08208.11 RLN91966.1 - 2.2 8.3 22.4 3.2 7.8 22.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Med19 PF10278.9 RLN91966.1 - 2.8 7.9 18.9 4.3 7.2 18.9 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 YqfQ PF14181.6 RLN91966.1 - 10 6.3 16.6 0.7 10.1 10.4 2.0 2 0 0 2 2 2 0 YqfQ-like protein FA_desaturase PF00487.24 RLN91967.1 - 1.1e-27 97.6 16.8 1.6e-27 97.0 16.8 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 RLN91967.1 - 7.7e-05 22.9 0.0 0.00017 21.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Ribosomal_L36e PF01158.18 RLN91968.1 - 5.3e-16 58.6 1.1 2.3e-09 37.4 0.1 2.4 2 1 1 3 3 3 2 Ribosomal protein L36e RRM_1 PF00076.22 RLN91969.1 - 4.8e-57 189.7 11.6 1.5e-12 47.2 0.1 8.6 7 1 0 7 7 7 7 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RLN91969.1 - 8.9e-05 22.3 1.3 0.009 15.9 0.1 4.4 6 0 0 6 6 6 1 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 RLN91969.1 - 0.0014 18.4 0.0 0.42 10.4 0.0 3.1 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain FA_desaturase PF00487.24 RLN91970.1 - 6.1e-27 95.1 13.6 9.2e-27 94.5 13.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 RLN91970.1 - 8.6e-07 29.2 0.0 1.9e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DUF2670 PF10875.8 RLN91970.1 - 0.045 13.9 0.5 4 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2670) RcsC PF09456.10 RLN91971.1 - 0.13 12.3 0.0 2.6 8.1 0.1 2.5 2 0 0 2 2 2 0 RcsC Alpha-Beta-Loop (ABL) CDC45 PF02724.14 RLN91971.1 - 0.19 10.0 8.1 0.3 9.3 8.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RLN91971.1 - 4.2 5.5 11.2 6.8 4.8 11.2 1.2 1 0 0 1 1 1 0 Nop14-like family Aa_trans PF01490.18 RLN91972.1 - 2.2e-47 161.7 5.7 4e-47 160.8 5.7 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein MscS_TM PF12794.7 RLN91972.1 - 4.2 6.1 13.2 0.31 9.8 0.1 3.2 3 0 0 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 Aa_trans PF01490.18 RLN91974.1 - 1e-30 106.8 12.6 1.5e-30 106.3 12.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3784 PF12650.7 RLN91974.1 - 2 8.6 14.6 1.1 9.5 0.1 4.1 3 2 1 4 4 4 0 Domain of unknown function (DUF3784) Aa_trans PF01490.18 RLN91975.1 - 2.6e-44 151.6 16.7 3.6e-44 151.1 16.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MtN3_slv PF03083.16 RLN91976.1 - 5.1e-23 80.9 5.3 1.4e-16 60.3 1.6 2.5 2 1 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Phage_holin_3_1 PF05106.12 RLN91976.1 - 0.0095 16.4 1.6 0.023 15.1 1.6 1.6 1 0 0 1 1 1 1 Phage holin family (Lysis protein S) DUF1772 PF08592.11 RLN91976.1 - 0.096 13.0 6.7 0.056 13.8 1.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) MtN3_slv PF03083.16 RLN91977.1 - 1.3e-22 79.6 12.7 1.5e-13 50.6 2.6 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RLN91977.1 - 9.6 6.1 20.5 0.67 9.8 1.8 4.6 4 1 1 5 5 5 0 PQ loop repeat zf-rbx1 PF12678.7 RLN91978.1 - 2.7e-09 37.2 4.1 5.1e-09 36.3 4.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 RLN91978.1 - 3.4e-09 36.4 5.7 5.5e-09 35.7 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN91978.1 - 6.7e-09 35.9 5.7 1.1e-08 35.2 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RLN91978.1 - 4.2e-08 32.9 3.0 6.8e-08 32.3 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN91978.1 - 3.5e-06 26.8 4.9 6.3e-06 26.0 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RLN91978.1 - 2.2e-05 24.4 1.9 4.6e-05 23.4 1.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 RLN91978.1 - 0.00063 19.6 4.9 0.0011 18.8 4.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN91978.1 - 0.00096 19.1 3.4 0.0016 18.3 3.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 RLN91978.1 - 0.018 14.8 4.0 0.021 14.6 2.3 2.0 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 RLN91978.1 - 0.13 12.3 4.4 0.13 12.3 1.3 2.3 1 1 1 2 2 2 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 RLN91978.1 - 0.24 11.1 5.6 0.45 10.2 5.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 RLN91978.1 - 0.34 10.8 1.5 0.8 9.6 1.5 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein RINGv PF12906.7 RLN91978.1 - 1.3 9.2 5.8 2.4 8.4 5.8 1.4 1 0 0 1 1 1 0 RING-variant domain zf-rbx1 PF12678.7 RLN91979.1 - 4.8e-11 42.8 2.4 9.8e-11 41.8 2.4 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 RLN91979.1 - 2.3e-10 40.6 2.7 4.6e-10 39.7 2.7 1.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN91979.1 - 3.9e-07 29.8 0.8 3.9e-07 29.8 0.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN91979.1 - 1.2e-06 28.3 0.2 2.6e-06 27.2 0.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN91979.1 - 1.9e-06 27.5 4.9 6.2e-06 25.8 0.4 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 RLN91979.1 - 2.9e-06 27.3 1.5 4e-06 26.8 1.5 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 RLN91979.1 - 3.7e-06 26.8 1.5 7.7e-06 25.8 1.5 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RLN91979.1 - 8.5e-06 25.5 3.1 2.3e-05 24.1 3.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN91979.1 - 3.7e-05 23.6 3.5 0.00016 21.5 3.1 2.0 1 1 1 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 RLN91979.1 - 0.0012 18.4 1.0 0.0012 18.4 1.0 1.8 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 RLN91979.1 - 0.018 15.2 1.1 0.047 13.9 0.2 1.9 1 1 1 2 2 2 0 Zinc-ribbon like family FANCL_C PF11793.8 RLN91979.1 - 0.019 15.1 1.1 0.031 14.4 1.1 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 RLN91979.1 - 0.1 12.8 0.2 0.1 12.8 0.2 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 RLN91979.1 - 0.13 12.1 0.3 0.21 11.4 0.3 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 RLN91979.1 - 0.23 11.6 2.0 0.97 9.6 2.0 2.0 1 1 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 RLN91979.1 - 0.34 10.8 4.2 1.1 9.2 4.3 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 YL1 PF05764.13 RLN91980.1 - 0.0059 16.8 18.6 0.0064 16.7 18.6 1.2 1 0 0 1 1 1 1 YL1 nuclear protein BUD22 PF09073.10 RLN91980.1 - 0.04 13.3 17.8 0.048 13.0 17.8 1.0 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.12 RLN91980.1 - 0.042 12.5 18.8 0.048 12.3 18.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 RLN91980.1 - 3.7 5.6 18.5 3.8 5.6 18.5 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RLN91980.1 - 4.2 5.5 15.5 4.4 5.5 15.5 1.0 1 0 0 1 1 1 0 CDC45-like protein CCDC106 PF15794.5 RLN91980.1 - 5.8 6.6 10.6 4.4 7.0 9.7 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 Ank_2 PF12796.7 RLN91982.1 - 1.4e-48 163.4 6.0 9.6e-14 51.7 0.0 4.4 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 RLN91982.1 - 1.2e-35 120.4 5.1 3.1e-05 24.2 0.0 8.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 RLN91982.1 - 2.1e-35 120.3 7.3 1.4e-09 38.0 0.1 5.8 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN91982.1 - 2.7e-33 113.9 0.9 2.5e-09 37.5 0.0 5.2 1 1 1 4 4 4 4 Ankyrin repeats (many copies) Pkinase PF00069.25 RLN91982.1 - 5.4e-30 104.6 0.0 1e-29 103.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.6 RLN91982.1 - 9.9e-30 99.3 0.6 0.0034 17.8 0.0 7.8 8 0 0 8 8 8 6 Ankyrin repeat Pkinase_Tyr PF07714.17 RLN91982.1 - 1.4e-28 99.9 0.0 2.4e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN91982.1 - 0.0048 16.2 0.0 0.0089 15.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YfmQ PF10787.9 RLN91982.1 - 0.052 13.3 0.0 3.1 7.6 0.0 2.4 1 1 1 2 2 2 0 Uncharacterised protein from bacillus cereus group COX1 PF00115.20 RLN91983.1 - 6.1e-149 496.5 55.4 7.6e-149 496.2 55.4 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Asp PF00026.23 RLN91984.1 - 2.7e-19 69.8 1.6 4.2e-19 69.1 1.6 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RLN91984.1 - 1.2e-14 55.0 3.9 2.4e-14 54.0 3.9 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 RLN91984.1 - 6.2e-11 42.3 0.0 1.1e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal HIG_1_N PF04588.13 RLN91984.1 - 0.032 14.4 0.1 0.057 13.7 0.1 1.4 1 0 0 1 1 1 0 Hypoxia induced protein conserved region Amnionless PF14828.6 RLN91984.1 - 0.035 12.9 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 Amnionless MAP17 PF15807.5 RLN91984.1 - 0.042 14.1 0.1 0.084 13.1 0.1 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 EphA2_TM PF14575.6 RLN91984.1 - 0.1 13.5 0.1 0.25 12.3 0.1 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAM176 PF14851.6 RLN91984.1 - 0.16 11.6 4.0 0.62 9.7 4.0 2.0 1 1 0 1 1 1 0 FAM176 family zf-B_box PF00643.24 RLN91985.1 - 1.9e-14 53.5 15.7 1.8e-07 31.2 1.3 2.4 2 0 0 2 2 2 2 B-box zinc finger PARP PF00644.20 RLN91985.1 - 0.0079 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain CEBP_ZZ PF16366.5 RLN91985.1 - 0.015 15.5 9.2 0.073 13.3 4.1 2.4 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain IBR PF01485.21 RLN91985.1 - 0.05 13.8 8.8 0.07 13.4 1.5 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Eapp_C PF10238.9 RLN91985.1 - 0.64 10.1 4.4 2.9 8.0 0.6 2.5 2 0 0 2 2 2 0 E2F-associated phosphoprotein FAR1 PF03101.15 RLN91986.1 - 0.067 13.9 0.8 0.17 12.6 0.8 1.9 1 1 0 1 1 1 0 FAR1 DNA-binding domain DUF5575 PF17738.1 RLN91986.1 - 0.13 11.3 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5575) Alkyl_sulf_C PF14864.6 RLN91986.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal Motile_Sperm PF00635.26 RLN91987.1 - 3.1e-16 59.2 0.0 5.9e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain SPX PF03105.19 RLN91988.1 - 1.4e-08 35.1 30.9 0.0016 18.4 4.1 5.2 3 1 2 5 5 5 5 SPX domain TssC PF17541.2 RLN91988.1 - 0.05 12.4 0.3 0.085 11.7 0.3 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB Ank_4 PF13637.6 RLN91989.1 - 1.3e-06 28.9 0.0 2.2e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN91989.1 - 1.6e-05 25.4 0.0 1.7e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN91989.1 - 6.6e-05 23.1 0.1 0.049 14.0 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN91989.1 - 0.00017 21.7 0.0 0.00041 20.6 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 RLN91989.1 - 0.0021 18.4 0.4 0.0073 16.7 0.0 2.0 3 0 0 3 3 3 1 Ankyrin repeat Asp PF00026.23 RLN91990.1 - 1.5e-22 80.4 3.0 1.8e-16 60.5 0.2 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 RLN91990.1 - 4.1e-20 72.8 0.9 8.4e-20 71.7 0.9 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 RLN91990.1 - 3.6e-05 23.6 0.0 0.00019 21.3 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal GATase PF00117.28 RLN91991.1 - 8.7e-45 152.8 0.0 1e-44 152.6 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 RLN91991.1 - 0.0085 15.9 0.4 0.13 12.0 0.4 2.4 1 1 0 1 1 1 1 Peptidase C26 B9-C2 PF07162.11 RLN91992.1 - 1.2e-21 77.6 0.0 1.9e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein EF-hand_1 PF00036.32 RLN91993.1 - 1.8e-32 108.4 17.2 3.8e-09 35.5 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RLN91993.1 - 1.2e-29 102.5 10.7 4.5e-16 59.1 0.7 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN91993.1 - 1.5e-25 86.9 12.0 1.6e-09 37.0 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 RLN91993.1 - 1.2e-24 85.9 14.7 1.6e-12 47.1 1.1 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 RLN91993.1 - 1.1e-15 56.3 16.3 1.2e-05 24.5 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 RLN91993.1 - 5.7e-15 55.4 0.5 3.6e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 RLN91993.1 - 0.00018 21.4 11.7 3.5 7.6 0.3 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 RLN91993.1 - 0.00023 21.4 1.5 0.21 11.9 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain Caleosin PF05042.13 RLN91993.1 - 0.0011 18.9 1.2 1.7 8.5 0.0 3.7 1 1 3 4 4 4 1 Caleosin related protein SurA_N_2 PF13623.6 RLN91993.1 - 0.0024 17.7 1.0 0.57 10.0 0.1 2.4 1 1 0 2 2 2 1 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 RLN91993.1 - 0.0035 17.6 1.4 1.8 8.9 0.4 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 RLN91993.1 - 0.0081 16.1 1.1 0.043 13.8 0.2 2.2 1 1 0 2 2 2 1 Tellurite resistance protein TerB DUF3349 PF11829.8 RLN91993.1 - 0.014 16.2 0.9 6.3 7.7 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3349) SurA_N_3 PF13624.6 RLN91993.1 - 0.014 15.2 0.8 0.11 12.3 0.2 2.0 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_11 PF08976.11 RLN91993.1 - 0.015 16.1 0.3 0.2 12.5 0.1 2.1 1 1 1 2 2 2 0 EF-hand domain Toprim_2 PF13155.6 RLN91993.1 - 0.017 15.6 0.4 5.8 7.4 0.1 2.7 1 1 2 3 3 3 0 Toprim-like Ribosomal_S3Ae PF01015.18 RLN91993.1 - 0.021 14.4 0.1 0.036 13.7 0.1 1.3 1 0 0 1 1 1 0 Ribosomal S3Ae family ERAP1_C PF11838.8 RLN91993.1 - 0.055 13.0 0.0 0.073 12.6 0.0 1.1 1 0 0 1 1 1 0 ERAP1-like C-terminal domain Glyco_transf_92 PF01697.27 RLN91993.1 - 0.068 12.8 0.2 0.094 12.3 0.2 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 92 SUB1_ProdP9 PF18213.1 RLN91993.1 - 0.075 12.9 1.4 0.28 11.0 0.1 2.1 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 MerR-DNA-bind PF09278.11 RLN91993.1 - 0.099 13.2 1.7 3.9 8.1 0.1 3.2 3 1 1 4 4 4 0 MerR, DNA binding Arc_PepC PF06819.11 RLN91993.1 - 0.34 11.1 4.0 0.19 11.9 1.6 1.8 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain Ank_2 PF12796.7 RLN91994.1 - 5.6e-26 91.0 2.6 5e-13 49.5 0.5 2.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN91994.1 - 3.9e-18 63.7 0.5 0.00066 19.9 0.1 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 RLN91994.1 - 1.1e-17 63.8 1.9 2.9e-06 27.5 0.1 4.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN91994.1 - 8.4e-15 54.9 0.7 7.7e-08 32.7 0.4 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN91994.1 - 6.9e-14 51.6 2.8 4.4e-06 26.9 0.2 5.0 5 0 0 5 5 5 2 Ankyrin repeat DUF3039 PF11238.8 RLN91994.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) AAA_23 PF13476.6 RLN91994.1 - 0.12 12.9 2.6 0.19 12.2 2.6 1.4 1 0 0 1 1 1 0 AAA domain Csm1_N PF18504.1 RLN91994.1 - 0.33 11.3 12.3 1.9 8.9 1.1 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain Spc7 PF08317.11 RLN91994.1 - 1.3 7.8 13.9 2.1 7.1 13.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Sec2p PF06428.11 RLN91994.1 - 4.7 7.2 16.3 0.13 12.3 3.7 2.8 1 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Exo5 PF09810.9 RLN91995.1 - 0.0084 15.6 0.4 0.0095 15.5 0.4 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease ANAPC4_WD40 PF12894.7 RLN91996.1 - 0.00026 21.2 0.0 0.71 10.2 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RLN91996.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 RLN91996.1 - 0.48 11.4 7.1 0.49 11.4 0.1 4.0 4 1 0 4 4 4 0 WD domain, G-beta repeat DUF3160 PF11369.8 RLN91997.1 - 5.5e-113 378.6 0.0 6.4e-64 216.5 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3160) Tnp_DNA_bind PF14706.6 RLN91997.1 - 0.029 14.2 0.3 1.1 9.2 0.0 2.7 2 0 0 2 2 2 0 Transposase DNA-binding NAD_binding_10 PF13460.6 RLN91998.1 - 7.5e-19 68.3 0.0 1.2e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 RLN91998.1 - 1.4e-12 47.2 0.0 4.7e-12 45.5 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 RLN91998.1 - 1.3e-08 34.6 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 RLN91998.1 - 2.2e-08 33.9 0.1 3.6e-08 33.3 0.1 1.3 1 1 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 RLN91998.1 - 0.00098 18.6 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 RLN91998.1 - 0.01 15.0 0.1 0.022 13.9 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain GPDPase_memb PF10110.9 RLN92000.1 - 0.0016 17.3 2.9 0.0021 16.9 2.9 1.0 1 0 0 1 1 1 1 Membrane domain of glycerophosphoryl diester phosphodiesterase DUF4205 PF13898.6 RLN92001.1 - 3.2e-64 217.0 0.0 9.6e-59 199.0 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4205) LRR_8 PF13855.6 RLN92002.1 - 1.3e-08 34.4 3.3 0.16 11.7 0.0 6.3 3 1 4 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 RLN92002.1 - 0.0071 16.7 10.6 1.2 9.7 0.2 5.9 4 2 2 6 6 6 2 Leucine Rich repeats (2 copies) ORC4_C PF14629.6 RLN92003.1 - 9.5e-16 57.8 0.1 1.4e-15 57.2 0.1 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 RLN92003.1 - 4.7e-06 27.1 0.4 4.7e-06 27.1 0.4 2.5 3 2 0 3 3 3 1 AAA ATPase domain ATPase_2 PF01637.18 RLN92003.1 - 0.0062 16.5 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 RLN92003.1 - 0.019 15.4 0.0 0.042 14.3 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RT_RNaseH_2 PF17919.1 RLN92003.1 - 0.14 12.2 0.2 32 4.6 0.0 3.0 3 0 0 3 3 3 0 RNase H-like domain found in reverse transcriptase B56 PF01603.20 RLN92005.1 - 1.1e-12 47.7 0.0 1.8e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) AAA PF00004.29 RLN92006.1 - 1.1e-41 142.4 0.0 2.2e-39 134.9 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Synaptobrevin PF00957.21 RLN92006.1 - 5.4e-29 99.8 0.1 1.1e-28 98.8 0.1 1.6 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 RLN92006.1 - 6.2e-23 80.6 0.1 1.3e-22 79.7 0.1 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain Bromodomain PF00439.25 RLN92006.1 - 2e-18 66.2 0.5 5.7e-18 64.8 0.3 1.9 2 0 0 2 2 1 1 Bromodomain AAA_lid_3 PF17862.1 RLN92006.1 - 7.4e-10 38.5 0.1 3.1e-09 36.5 0.1 2.1 2 0 0 2 2 2 1 AAA+ lid domain PHD PF00628.29 RLN92006.1 - 1.8e-05 24.5 8.4 5e-05 23.1 8.4 1.8 1 1 0 1 1 1 1 PHD-finger AAA_2 PF07724.14 RLN92006.1 - 1.9e-05 24.9 0.0 6.9e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 RLN92006.1 - 0.00038 20.8 1.6 0.029 14.6 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN92006.1 - 0.0024 18.3 0.2 0.0024 18.3 0.2 5.1 3 2 1 4 4 4 1 AAA ATPase domain Parvo_NS1 PF01057.17 RLN92006.1 - 0.005 16.0 0.0 0.013 14.6 0.0 1.6 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.17 RLN92006.1 - 0.005 16.6 0.3 0.13 12.0 0.0 2.7 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_18 PF13238.6 RLN92006.1 - 0.011 16.3 0.0 0.05 14.2 0.0 2.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 RLN92006.1 - 0.012 15.6 0.1 0.24 11.4 0.0 2.9 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RLN92006.1 - 0.035 13.9 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 RLN92006.1 - 0.047 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 RLN92006.1 - 0.072 13.3 0.0 0.072 13.3 0.0 3.2 4 0 0 4 4 3 0 AAA domain AAA_24 PF13479.6 RLN92006.1 - 0.11 12.2 0.0 0.33 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RLN92006.1 - 0.11 12.7 0.0 0.11 12.7 0.0 3.5 5 0 0 5 5 3 0 AAA domain Sigma54_activat PF00158.26 RLN92006.1 - 0.12 12.1 0.0 3.5 7.3 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 RLN92006.1 - 0.15 12.5 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Zf_RING PF16744.5 RLN92006.1 - 1 9.5 4.7 2.4 8.4 4.7 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger zf-PHD-like PF15446.6 RLN92006.1 - 2.1 7.9 5.7 5.5 6.6 5.7 1.7 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Potass_KdpF PF09604.10 RLN92006.1 - 6.8 6.8 8.2 13 5.9 8.2 1.5 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) FYVE_2 PF02318.16 RLN92007.1 - 6.2 7.1 6.8 15 5.9 6.8 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 RLN92007.1 - 6.7 6.9 9.2 17 5.7 9.2 1.6 1 0 0 1 1 1 0 FYVE zinc finger Motile_Sperm PF00635.26 RLN92008.1 - 2.5e-06 27.3 0.0 4.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain COesterase PF00135.28 RLN92009.1 - 2e-91 307.4 0.0 2.5e-91 307.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RLN92009.1 - 5.4e-06 26.4 0.6 0.0065 16.3 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN92009.1 - 0.047 13.2 0.9 0.082 12.4 0.9 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family 4HBT PF03061.22 RLN92010.1 - 1.9e-12 47.3 0.2 4e-12 46.3 0.2 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Myb_DNA-binding PF00249.31 RLN92011.1 - 3.3e-33 113.6 4.6 4.1e-13 49.3 0.0 3.3 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN92011.1 - 8.4e-25 86.8 0.2 5.2e-12 45.8 0.2 3.0 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 RLN92011.1 - 0.0018 18.4 0.0 0.076 13.2 0.0 2.7 2 0 0 2 2 2 1 Rap1 Myb domain SLIDE PF09111.10 RLN92011.1 - 0.0094 16.0 0.0 5.3 7.1 0.0 2.6 2 1 1 3 3 3 2 SLIDE Rap1_C PF11626.8 RLN92011.1 - 0.27 11.3 4.7 20 5.4 4.7 2.8 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Pkinase PF00069.25 RLN92014.1 - 3.6e-40 138.0 0.0 4.7e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92014.1 - 1.4e-15 57.3 0.0 1.7e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN92014.1 - 0.0053 16.1 0.0 0.0085 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN92014.1 - 0.12 11.1 0.0 0.26 10.0 0.0 1.6 1 1 0 1 1 1 0 Fungal protein kinase DUF1679 PF07914.11 RLN92014.1 - 0.23 10.3 0.0 0.36 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) HHH_8 PF14716.6 RLN92018.1 - 1.9e-16 60.2 0.2 5.6e-08 33.0 0.0 3.2 3 0 0 3 3 3 2 Helix-hairpin-helix domain HEAT_PBS PF03130.16 RLN92018.1 - 0.14 12.9 1.0 1.6 9.6 0.1 2.9 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat RNA_pol_3_Rpc31 PF11705.8 RLN92018.1 - 0.24 11.6 15.2 0.095 12.9 8.7 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF913 PF06025.12 RLN92018.1 - 0.27 10.2 1.6 0.45 9.4 1.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 RLN92018.1 - 0.62 8.8 3.7 0.71 8.6 3.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4820 PF16091.5 RLN92018.1 - 0.73 9.2 3.6 0.55 9.6 1.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Myc_N PF01056.18 RLN92018.1 - 1.2 9.0 6.8 0.32 10.9 1.1 2.0 2 0 0 2 2 2 0 Myc amino-terminal region NPR3 PF03666.13 RLN92018.1 - 2.6 6.7 4.7 3.7 6.2 4.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NOA36 PF06524.12 RLN92018.1 - 4.3 6.6 12.9 0.59 9.4 6.7 2.0 2 0 0 2 2 2 0 NOA36 protein DUF4834 PF16118.5 RLN92018.1 - 4.8 8.2 6.0 1.3 10.0 2.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TPR_MLP1_2 PF07926.12 RLN92019.1 - 0.0042 17.1 9.0 0.0042 17.1 9.0 3.7 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein Rootletin PF15035.6 RLN92019.1 - 0.0062 16.6 7.8 0.0062 16.6 7.8 3.9 1 1 1 3 3 3 1 Ciliary rootlet component, centrosome cohesion Tyr_Deacylase PF02580.16 RLN92019.1 - 0.044 14.3 0.7 0.084 13.4 0.7 1.5 1 0 0 1 1 1 0 D-Tyr-tRNA(Tyr) deacylase DUF4878 PF12870.7 RLN92019.1 - 0.1 12.9 1.1 0.44 10.9 0.1 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4878) ADIP PF11559.8 RLN92019.1 - 0.18 11.9 40.8 0.23 11.5 8.8 3.8 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding FapA PF03961.13 RLN92019.1 - 0.48 9.0 15.6 0.47 9.0 6.0 2.4 1 1 1 2 2 2 0 Flagellar Assembly Protein A FliD_N PF02465.18 RLN92019.1 - 2.1 9.1 19.7 0.31 11.8 0.6 3.8 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF812 PF05667.11 RLN92019.1 - 2.5 6.9 33.5 21 3.9 33.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Cep57_CLD PF14073.6 RLN92019.1 - 6.2 6.8 38.7 0.046 13.7 21.4 4.0 1 1 2 4 4 4 0 Centrosome localisation domain of Cep57 SLC35F PF06027.12 RLN92020.1 - 2.1e-08 34.1 2.7 4.1e-08 33.1 2.7 1.4 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 RLN92020.1 - 2.4e-08 34.2 3.7 2.4e-08 34.2 3.7 3.3 2 1 1 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 RLN92020.1 - 7.7e-06 25.4 2.1 7.7e-06 25.4 2.1 1.4 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport Nuc_sug_transp PF04142.15 RLN92020.1 - 2.2e-05 23.8 3.5 3.5e-05 23.1 3.5 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 RLN92020.1 - 0.00061 19.1 3.5 0.001 18.4 3.5 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 RLN92020.1 - 0.0052 16.2 6.1 0.0092 15.4 6.1 1.4 1 0 0 1 1 1 1 Triose-phosphate Transporter family CRT-like PF08627.10 RLN92020.1 - 0.46 9.4 17.0 0.011 14.7 4.3 2.1 1 1 1 2 2 2 0 CRT-like, chloroquine-resistance transporter-like Eapp_C PF10238.9 RLN92021.1 - 3.6e-25 88.8 1.3 1.8e-21 76.8 0.0 2.4 1 1 1 2 2 2 2 E2F-associated phosphoprotein DUF1251 PF06856.11 RLN92021.1 - 0.024 14.4 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1251) Pkinase PF00069.25 RLN92022.1 - 8.9e-35 120.3 0.0 3.4e-23 82.4 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92022.1 - 5.2e-20 71.8 0.0 3.9e-08 32.9 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase FTA2 PF13095.6 RLN92022.1 - 0.006 16.2 0.0 0.24 11.0 0.0 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 RLN92022.1 - 0.028 13.7 0.0 0.73 9.1 0.0 2.7 3 0 0 3 3 3 0 Kinase-like Kdo PF06293.14 RLN92022.1 - 0.033 13.5 0.3 0.087 12.2 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Chloroplast_duf PF14476.6 RLN92022.1 - 0.06 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Petal formation-expressed APH PF01636.23 RLN92022.1 - 0.11 12.4 3.4 0.12 12.3 0.0 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family DUF5315 PF17242.2 RLN92022.1 - 6.1 6.7 9.3 1.7 8.5 0.8 3.3 3 1 0 3 3 3 0 Disordered region of unknown function (DUF5315) Methyltransf_8 PF05148.15 RLN92026.1 - 5.6e-80 268.3 0.2 7.1e-43 147.0 0.0 2.1 2 0 0 2 2 2 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 RLN92026.1 - 2.2e-07 31.4 0.0 7.2e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN92026.1 - 0.00013 22.6 0.0 0.0036 18.0 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN92026.1 - 0.002 18.9 0.0 0.0077 17.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN92026.1 - 0.0079 16.0 0.0 0.083 12.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN92026.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MPS2 PF17060.5 RLN92026.1 - 0.1 11.9 0.1 0.21 10.8 0.0 1.4 1 1 0 1 1 1 0 Monopolar spindle protein 2 EF-hand_7 PF13499.6 RLN92027.1 - 0.11 13.0 0.0 0.6 10.6 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair Pkinase_Tyr PF07714.17 RLN92028.1 - 6.3e-40 137.1 0.0 9e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN92028.1 - 6.6e-40 137.1 0.0 1.2e-39 136.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain ABC2_membrane_2 PF12679.7 RLN92028.1 - 0.11 11.8 9.0 0.1 11.9 7.6 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein PH PF00169.29 RLN92029.1 - 7.7e-18 64.9 0.2 1.9e-07 31.6 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 RLN92029.1 - 5.8e-09 36.3 4.3 0.0032 17.9 0.5 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_12 PF16457.5 RLN92029.1 - 0.00016 22.2 1.6 0.24 11.9 0.1 2.9 2 1 0 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.6 RLN92029.1 - 0.0006 20.1 0.6 3.2 8.1 0.0 3.2 3 0 0 3 3 3 2 Pleckstrin homology domain PH_13 PF16652.5 RLN92029.1 - 0.0008 19.2 1.2 0.13 12.0 0.2 2.2 2 0 0 2 2 2 2 Pleckstrin homology domain PH_17 PF18012.1 RLN92029.1 - 0.0095 15.6 0.3 0.037 13.7 0.1 2.0 2 0 0 2 2 2 1 PH domain PH_4 PF15404.6 RLN92029.1 - 0.025 14.4 0.4 0.86 9.4 0.1 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain PH_9 PF15410.6 RLN92029.1 - 0.038 14.3 0.5 3 8.3 0.0 2.6 2 1 1 3 3 3 0 Pleckstrin homology domain PH_5 PF15405.6 RLN92029.1 - 0.14 12.2 0.1 11 6.1 0.0 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain DUF2849 PF11011.8 RLN92029.1 - 0.25 12.0 1.8 2.4 8.9 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2849) PIG-P PF08510.12 RLN92030.1 - 0.0065 16.4 0.6 0.0065 16.4 0.6 3.3 3 1 0 3 3 3 1 PIG-P PALP PF00291.25 RLN92031.1 - 9.1e-24 84.4 0.6 1.1e-23 84.1 0.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FMN_red PF03358.15 RLN92032.1 - 9.2e-22 77.4 0.0 1.4e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 RLN92032.1 - 3.2e-06 27.0 0.0 4.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold DUF4940 PF16298.5 RLN92032.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4940) Methyltransf_24 PF13578.6 RLN92033.1 - 3.4e-06 28.0 0.0 5.9e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Baseplate_J PF04865.14 RLN92033.1 - 0.057 12.6 0.0 0.078 12.1 0.0 1.1 1 0 0 1 1 1 0 Baseplate J-like protein Pro_CA PF00484.19 RLN92034.1 - 2e-48 164.6 0.1 3.6e-48 163.8 0.1 1.4 1 0 0 1 1 1 1 Carbonic anhydrase UBA PF00627.31 RLN92035.1 - 0.00014 21.7 0.3 0.00032 20.5 0.1 1.8 2 0 0 2 2 2 1 UBA/TS-N domain FAM212 PF15342.6 RLN92035.1 - 0.11 12.3 0.7 0.29 11.0 0.7 1.6 1 0 0 1 1 1 0 FAM212 family Peptidase_S49_N PF08496.10 RLN92036.1 - 0.69 10.0 6.3 0.28 11.3 1.2 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF3287 PF11690.8 RLN92036.1 - 0.71 9.6 5.4 1 9.1 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) CCDC53 PF10152.9 RLN92036.1 - 0.75 10.2 6.2 8.2 6.8 6.2 2.1 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex CENP-H PF05837.12 RLN92036.1 - 1.9 8.9 13.2 0.12 12.7 5.1 2.5 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Uso1_p115_C PF04871.13 RLN92036.1 - 2.3 8.6 9.8 1 9.7 3.8 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF724 PF05266.14 RLN92036.1 - 4.7 7.0 7.8 2.1 8.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Pro_CA PF00484.19 RLN92037.1 - 1e-42 146.0 0.8 1.4e-42 145.6 0.2 1.4 2 0 0 2 2 2 1 Carbonic anhydrase Pro_CA PF00484.19 RLN92038.1 - 1e-47 162.3 0.2 1.6e-47 161.7 0.2 1.3 1 0 0 1 1 1 1 Carbonic anhydrase Med14 PF08638.11 RLN92039.1 - 1.3e-44 151.9 0.1 2.8e-44 150.8 0.1 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 MnhB PF04039.13 RLN92039.1 - 0.068 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain related to MnhB subunit of Na+/H+ antiporter RRM_1 PF00076.22 RLN92042.1 - 1.2e-18 66.7 0.0 1.3e-08 34.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN92042.1 - 0.0029 17.7 0.1 0.0081 16.3 0.0 1.8 1 1 1 2 2 2 1 RNA recognition motif Limkain-b1 PF11608.8 RLN92042.1 - 0.025 14.6 0.1 0.17 12.0 0.0 2.3 2 1 0 2 2 2 0 Limkain b1 RRM_9 PF18444.1 RLN92042.1 - 0.18 11.7 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif RRM_3 PF08777.11 RLN92042.1 - 0.2 11.7 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Vps26 PF03643.15 RLN92043.1 - 4.2e-98 327.7 0.0 5.1e-98 327.4 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 RLN92043.1 - 0.049 13.7 0.0 4.3 7.4 0.0 2.9 2 1 1 3 3 3 0 Arrestin (or S-antigen), N-terminal domain UPRTase PF14681.6 RLN92044.1 - 1.6e-26 93.1 0.2 3.1e-26 92.1 0.2 1.4 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 RLN92044.1 - 0.0016 18.0 0.1 0.0029 17.1 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain HTH_7 PF02796.15 RLN92044.1 - 0.081 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 RLN92044.1 - 0.086 12.7 0.2 0.21 11.5 0.2 1.7 1 0 0 1 1 1 0 Homeodomain-like domain CytochromB561_N PF09786.9 RLN92044.1 - 0.45 9.5 3.0 0.64 8.9 3.0 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Borrelia_P83 PF05262.11 RLN92045.1 - 0.32 9.4 17.0 0.38 9.2 17.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein FYVE PF01363.21 RLN92046.1 - 4e-11 42.9 8.1 1.2e-10 41.4 8.1 1.8 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN92046.1 - 0.0016 18.6 3.3 0.0021 18.3 2.0 1.9 2 0 0 2 2 2 1 FYVE-type zinc finger NPCBM PF08305.11 RLN92047.1 - 2.1e-21 76.5 0.0 9.2e-21 74.5 0.0 2.0 2 0 0 2 2 2 1 NPCBM/NEW2 domain Laminin_G_3 PF13385.6 RLN92047.1 - 4.5e-13 49.6 0.0 1.5e-12 47.9 0.0 1.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily SPRY PF00622.28 RLN92047.1 - 4.4e-11 42.9 0.1 3.5e-09 36.8 0.0 2.4 2 0 0 2 2 2 1 SPRY domain UBA PF00627.31 RLN92047.1 - 4e-06 26.6 0.8 0.0015 18.4 0.2 2.9 2 0 0 2 2 2 2 UBA/TS-N domain F5_F8_type_C PF00754.25 RLN92047.1 - 0.0096 16.0 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 F5/8 type C domain UIM PF02809.20 RLN92047.1 - 0.016 15.1 4.1 0.15 12.0 4.1 2.9 1 0 0 1 1 1 0 Ubiquitin interaction motif zf-RanBP PF00641.18 RLN92047.1 - 0.051 12.9 3.8 0.11 11.9 3.8 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Neuralized PF07177.12 RLN92047.1 - 0.058 13.4 0.1 0.77 9.8 0.0 2.8 4 0 0 4 4 4 0 Neuralized Ribosomal_L50 PF10501.9 RLN92047.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Ribosomal subunit 39S ECH_1 PF00378.20 RLN92048.1 - 1.8e-35 122.5 0.0 2.2e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RLN92048.1 - 5.6e-21 75.4 0.0 1.9e-20 73.7 0.0 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SurA_N_3 PF13624.6 RLN92049.1 - 0.036 13.9 6.6 0.084 12.7 6.6 1.6 1 0 0 1 1 1 0 SurA N-terminal domain DUF5082 PF16888.5 RLN92049.1 - 2.7 8.3 17.4 1.5 9.1 0.6 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) Fib_alpha PF08702.10 RLN92049.1 - 2.9 8.1 12.1 0.46 10.7 5.7 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 RLN92049.1 - 4.4 5.1 14.8 6.3 4.6 14.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lectin_N PF03954.14 RLN92049.1 - 4.9 6.9 8.5 2.3 8.0 3.4 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Peptidase_S46 PF10459.9 RLN92049.1 - 5.5 5.5 15.3 7.4 5.1 15.3 1.1 1 0 0 1 1 1 0 Peptidase S46 TMCO5 PF14992.6 RLN92049.1 - 5.5 6.5 24.1 20 4.7 24.1 1.7 1 1 0 1 1 1 0 TMCO5 family YlqD PF11068.8 RLN92049.1 - 9.7 6.6 22.0 7.8 6.9 9.8 2.4 2 0 0 2 2 2 0 YlqD protein CPSase_L_D2 PF02786.17 RLN92050.1 - 2e-73 246.4 0.0 3.2e-73 245.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 RLN92050.1 - 9.2e-40 135.6 0.2 9.6e-39 132.3 0.0 2.6 3 0 0 3 3 3 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 RLN92050.1 - 2.4e-30 104.8 0.0 4.8e-30 103.8 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 RLN92050.1 - 7e-10 38.8 0.0 1.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HMGL-like PF00682.19 RLN92050.1 - 3.6e-07 30.0 0.0 7.7e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 HMGL-like ATP-grasp PF02222.22 RLN92050.1 - 2.4e-06 27.2 0.1 1.6e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 RLN92050.1 - 3.1e-05 24.1 0.0 6.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 RLN92050.1 - 0.0031 17.1 0.0 0.0066 16.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Ntox43 PF15537.6 RLN92050.1 - 0.044 13.8 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial toxin 43 ATPgrasp_Ter PF15632.6 RLN92050.1 - 0.055 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATPgrasp_ST PF14397.6 RLN92050.1 - 0.066 12.5 0.0 0.26 10.5 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp AMP-binding PF00501.28 RLN92051.1 - 3.1e-18 65.6 0.0 3.1e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme eIF2A PF08662.11 RLN92052.1 - 9.1e-70 234.5 0.0 5e-68 228.8 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 RLN92052.1 - 0.0046 17.8 0.9 49 5.0 0.0 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat PD40 PF07676.12 RLN92052.1 - 1.1 9.3 5.4 6.1 6.9 0.1 4.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat zf-BED PF02892.15 RLN92053.1 - 8.4e-05 22.5 0.2 0.00021 21.3 0.2 1.7 1 0 0 1 1 1 1 BED zinc finger Ctf8 PF09696.10 RLN92054.1 - 8.6e-07 29.4 0.0 4.7e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 Ctf8 Pkinase PF00069.25 RLN92055.1 - 2e-47 161.8 0.0 3.5e-47 161.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92055.1 - 2.1e-14 53.5 0.0 6.1e-14 51.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN92055.1 - 0.00012 22.1 0.0 0.0014 18.6 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN92055.1 - 0.0082 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RLN92055.1 - 0.0085 15.7 0.2 0.049 13.2 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 RLN92055.1 - 0.013 15.1 0.2 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.11 RLN92055.1 - 0.11 11.4 1.6 0.6 9.0 0.1 2.1 1 1 0 2 2 2 0 Poxvirus serine/threonine protein kinase Peptidase_S28 PF05577.12 RLN92056.1 - 4.7e-71 239.9 0.1 6.2e-71 239.5 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 RLN92056.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Macro PF01661.21 RLN92057.1 - 1.6e-13 50.7 0.0 2.6e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Macro domain L51_S25_CI-B8 PF05047.16 RLN92060.1 - 6.9e-11 41.9 0.3 1.1e-10 41.3 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Robl_LC7 PF03259.17 RLN92061.1 - 1.5e-07 31.1 0.0 2.1e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain DUF4070 PF13282.6 RLN92061.1 - 0.077 13.1 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) EF-hand_1 PF00036.32 RLN92062.1 - 1.9e-08 33.2 3.4 7e-07 28.3 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 RLN92062.1 - 2.9e-07 30.2 1.4 7.5e-06 25.7 0.3 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN92062.1 - 2.5e-05 23.5 0.2 0.0014 18.0 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RLN92062.1 - 2.8e-05 23.7 0.2 0.0094 15.8 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 RLN92062.1 - 0.00022 21.6 0.8 0.0032 17.9 0.7 2.6 1 1 0 1 1 1 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RLN92062.1 - 0.3 11.4 2.3 0.75 10.1 0.1 2.6 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region IMS PF00817.20 RLN92063.1 - 7.2e-25 87.7 0.1 9.9e-24 84.0 0.0 2.8 3 0 0 3 3 3 1 impB/mucB/samB family PDZ_6 PF17820.1 RLN92063.1 - 7.1e-12 45.0 0.0 0.00088 19.1 0.0 4.5 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.24 RLN92063.1 - 1.6e-08 34.8 0.0 0.3 11.5 0.0 4.4 4 0 0 4 4 4 3 PDZ domain zf_UBZ PF18439.1 RLN92063.1 - 7.6e-08 31.8 0.6 2.6e-07 30.1 0.6 2.0 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 RLN92063.1 - 0.041 14.6 0.2 0.25 12.0 0.1 2.5 2 0 0 2 2 2 0 impB/mucB/samB family C-terminal domain AKAP7_RIRII_bdg PF10470.9 RLN92063.1 - 0.071 13.2 0.3 0.32 11.1 0.3 2.1 1 0 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein Patched PF02460.18 RLN92064.1 - 4.7e-68 230.1 17.9 4e-45 154.2 0.2 3.3 2 1 1 3 3 3 2 Patched family Sterol-sensing PF12349.8 RLN92064.1 - 9.9e-35 119.6 7.3 9.9e-35 119.6 7.3 3.1 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation NPC1_N PF16414.5 RLN92064.1 - 1.7e-20 73.6 15.0 4.6e-20 72.2 14.6 1.9 2 0 0 2 2 2 1 Niemann-Pick C1 N terminus MMPL PF03176.15 RLN92064.1 - 0.44 9.4 10.5 0.7 8.8 6.4 2.6 2 0 0 2 2 2 0 MMPL family ACR_tran PF00873.19 RLN92064.1 - 6.7 4.2 13.4 0.21 9.2 7.3 1.5 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family Methyltransf_16 PF10294.9 RLN92065.1 - 2.4e-23 82.7 0.0 3.4e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 RLN92065.1 - 5.2e-05 22.8 0.0 7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 RLN92065.1 - 7.5e-05 23.4 0.0 0.00013 22.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RLN92065.1 - 8.1e-05 22.1 0.1 0.0001 21.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 RLN92065.1 - 0.0006 19.7 0.0 0.00071 19.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN92065.1 - 0.001 19.7 0.0 0.0018 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 RLN92065.1 - 0.092 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Antibiotic_NAT PF02522.14 RLN92067.1 - 0.068 13.0 0.4 0.19 11.5 0.1 2.0 2 0 0 2 2 2 0 Aminoglycoside 3-N-acetyltransferase NDUFB10 PF10249.9 RLN92067.1 - 0.077 13.5 3.5 1 9.8 0.1 2.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit 10 ANAPC4 PF12896.7 RLN92067.1 - 0.15 11.5 2.7 0.26 10.7 0.9 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 Tnp_22_trimer PF17489.2 RLN92067.1 - 0.2 11.7 7.7 3.7 7.6 0.4 4.6 5 0 0 5 5 5 0 L1 transposable element trimerization domain Sulfatase_C PF14707.6 RLN92067.1 - 5.5 7.8 10.1 11 6.8 0.1 4.0 2 2 2 4 4 4 0 C-terminal region of aryl-sulfatase DUF1664 PF07889.12 RLN92067.1 - 5.9 6.9 10.6 9.2 6.3 1.5 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) NPA PF16469.5 RLN92067.1 - 6.6 7.3 8.7 4 8.1 3.0 3.4 3 1 0 3 3 3 0 Nematode polyprotein allergen ABA-1 NPV_P10 PF05531.12 RLN92067.1 - 8.2 7.0 8.6 14 6.2 0.2 4.3 4 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein PAF-AH_p_II PF03403.13 RLN92068.1 - 6.9e-05 21.5 0.0 7.2e-05 21.5 0.0 1.0 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II 2-oxoacid_dh PF00198.23 RLN92069.1 - 1.8e-69 233.8 0.0 2.3e-69 233.4 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 RLN92069.1 - 1.4e-11 44.0 0.0 3.4e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 RLN92069.1 - 0.075 12.9 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like S36_mt PF10937.8 RLN92069.1 - 0.097 14.3 0.1 0.2 13.2 0.1 1.7 1 1 0 1 1 1 0 Ribosomal protein S36, mitochondrial Pkinase PF00069.25 RLN92070.1 - 4.1e-67 226.3 0.0 7e-67 225.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92070.1 - 1.1e-47 162.5 0.0 1.5e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN92070.1 - 2.1e-05 23.5 0.0 3.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN92070.1 - 0.00032 20.1 0.1 0.00091 18.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 RLN92070.1 - 0.0016 18.4 2.6 0.17 11.8 0.2 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Rota_NS26 PF01525.16 RLN92070.1 - 0.015 15.3 0.6 0.026 14.6 0.6 1.2 1 0 0 1 1 1 0 Rotavirus NS26 Kdo PF06293.14 RLN92070.1 - 0.028 13.8 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 RLN92070.1 - 0.068 13.3 2.0 0.091 12.9 0.0 2.2 3 0 0 3 3 3 0 ABC1 family Haspin_kinase PF12330.8 RLN92070.1 - 0.13 11.2 0.0 0.37 9.7 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain BLOC1_2 PF10046.9 RLN92071.1 - 0.0088 16.3 26.5 0.067 13.5 0.3 6.1 5 1 0 6 6 6 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tup_N PF08581.10 RLN92071.1 - 0.024 14.9 4.0 0.024 14.9 4.0 5.6 5 1 1 6 6 6 0 Tup N-terminal NPV_P10 PF05531.12 RLN92071.1 - 0.15 12.6 11.0 5.1 7.6 0.2 5.3 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 RLN92071.1 - 0.79 9.8 22.7 4.2 7.4 0.4 5.5 5 1 1 6 6 6 0 Protein of unknown function (DUF1664) EzrA PF06160.12 RLN92071.1 - 4.6 5.3 32.9 0.018 13.3 5.8 3.7 3 1 0 3 3 3 0 Septation ring formation regulator, EzrA IFT81_CH PF18383.1 RLN92072.1 - 1.2e-30 106.3 0.0 1.3e-30 106.2 0.0 1.0 1 0 0 1 1 1 1 Intraflagellar transport 81 calponin homology domain Glyco_hydro_30 PF02055.16 RLN92073.1 - 3.1e-84 282.9 0.3 4.2e-84 282.5 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Ricin_B_lectin PF00652.22 RLN92073.1 - 9.4e-15 55.0 7.0 1.4e-09 38.2 1.3 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Glyco_hydro_30C PF17189.4 RLN92073.1 - 5.9e-08 32.8 0.1 1.5e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 RLN92073.1 - 2.4e-07 30.3 0.0 4.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 RLN92073.1 - 5e-05 23.1 0.0 0.00018 21.2 0.0 1.7 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 RicinB_lectin_2 PF14200.6 RLN92073.1 - 0.0067 17.1 0.3 0.017 15.8 0.3 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_30 PF02055.16 RLN92074.1 - 1.6e-81 274.0 0.4 2e-81 273.7 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Ricin_B_lectin PF00652.22 RLN92074.1 - 1.6e-10 41.3 4.1 1.1e-07 32.2 0.9 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Glyco_hydro_30C PF17189.4 RLN92074.1 - 2.5e-08 34.0 0.1 7e-08 32.6 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 RLN92074.1 - 7e-07 28.8 0.0 1.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 RLN92074.1 - 2.8e-05 23.9 0.0 6.5e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 RicinB_lectin_2 PF14200.6 RLN92074.1 - 0.0056 17.4 0.4 0.014 16.1 0.4 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like TAT_signal PF10518.9 RLN92074.1 - 9.2 6.3 7.0 0.49 10.3 0.8 2.3 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Tubulin_C PF03953.17 RLN92075.1 - 1.2e-21 77.2 0.0 1.6e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain DUF1765 PF08578.10 RLN92077.1 - 0.00017 22.0 5.0 0.0004 20.8 5.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Glyco_hydro_7 PF00840.20 RLN92079.1 - 7.5e-79 265.5 0.9 7.5e-79 265.5 0.9 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 7 DHHC PF01529.20 RLN92081.1 - 4.3e-24 85.1 2.5 4.3e-24 85.1 2.5 2.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 RLN92081.1 - 1e-21 77.3 5.4 3.7e-08 33.8 0.0 4.2 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN92081.1 - 2e-18 66.5 4.9 2.5e-06 27.9 0.3 6.1 3 1 3 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN92081.1 - 2.7e-14 51.8 3.5 0.0091 16.4 0.1 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 RLN92081.1 - 6e-13 48.7 6.7 1.1e-06 28.8 1.9 4.3 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN92081.1 - 3.8e-10 39.8 8.0 0.031 14.7 1.1 6.7 7 0 0 7 7 7 3 Ankyrin repeat HA PF03457.14 RLN92082.1 - 1.2e-35 121.7 7.0 1.2e-05 25.5 0.1 8.8 8 0 0 8 8 8 7 Helicase associated domain CCT PF06203.14 RLN92082.1 - 2.5e-16 59.4 11.2 5.3e-16 58.4 11.2 1.6 1 0 0 1 1 1 1 CCT motif Methyltransf_5 PF01795.19 RLN92083.1 - 3.3e-74 250.2 1.5 1.5e-66 225.0 0.0 2.0 2 0 0 2 2 2 2 MraW methylase family Methyltransf_25 PF13649.6 RLN92083.1 - 7.7e-06 26.5 0.1 1.9e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN92083.1 - 0.0027 17.5 0.0 0.0046 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN92083.1 - 0.017 15.8 0.0 0.048 14.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Sulfotransfer_3 PF13469.6 RLN92083.1 - 0.028 14.8 0.3 0.12 12.7 0.0 2.1 2 1 0 2 2 2 0 Sulfotransferase family MTS PF05175.14 RLN92083.1 - 0.05 13.1 0.0 0.13 11.8 0.0 1.6 1 1 1 2 2 2 0 Methyltransferase small domain Methyltransf_11 PF08241.12 RLN92083.1 - 0.054 14.2 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 RLN92083.1 - 0.062 13.0 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 HHH_3 PF12836.7 RLN92083.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif PIN_8 PF18476.1 RLN92084.1 - 0.57 10.0 5.0 0.99 9.2 2.6 1.9 1 1 1 2 2 2 0 PIN like domain DUF3106 PF11304.8 RLN92084.1 - 0.73 10.3 5.3 0.78 10.2 2.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) DARPP-32 PF05395.12 RLN92084.1 - 0.86 9.8 4.5 1.7 8.8 4.2 1.7 1 1 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Ank_2 PF12796.7 RLN92085.1 - 9.6e-23 80.6 3.6 1.5e-10 41.5 0.3 4.9 3 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN92085.1 - 5e-22 78.0 0.2 2.8e-06 27.7 0.0 6.7 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN92085.1 - 1.2e-20 73.0 1.3 8.8e-05 22.8 0.1 6.8 6 1 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 RLN92085.1 - 1.4e-19 69.9 8.0 1.8e-05 24.9 0.1 6.4 4 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN92085.1 - 8.6e-12 44.2 4.5 2 9.2 0.0 8.6 9 0 0 9 9 9 3 Ankyrin repeat Mago_nashi PF02792.14 RLN92085.1 - 0.029 14.5 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 Mago nashi protein GCFC PF07842.12 RLN92085.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein PSD1 PF07587.11 RLN92088.1 - 0.0063 16.0 0.0 0.0093 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1553) Pkinase PF00069.25 RLN92089.1 - 3.2e-07 30.0 0.0 4.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain GRIP PF01465.20 RLN92089.1 - 0.099 12.6 0.0 3.5 7.6 0.0 2.4 2 0 0 2 2 2 0 GRIP domain bZIP_1 PF00170.21 RLN92090.1 - 9.7e-05 22.4 1.9 0.019 15.1 0.4 3.3 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 RLN92090.1 - 0.00031 20.8 11.2 0.0094 16.0 1.0 3.7 3 0 0 3 3 3 2 Basic region leucine zipper HALZ PF02183.18 RLN92090.1 - 0.00072 19.7 0.8 0.15 12.3 0.2 3.3 3 0 0 3 3 3 1 Homeobox associated leucine zipper CLZ PF16526.5 RLN92090.1 - 0.00075 19.8 1.1 0.24 11.8 0.5 2.7 2 1 0 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BST2 PF16716.5 RLN92090.1 - 0.02 15.5 1.6 0.02 15.5 1.6 3.0 4 0 0 4 4 4 0 Bone marrow stromal antigen 2 NRBF2 PF08961.10 RLN92090.1 - 0.023 14.3 2.9 0.046 13.3 2.4 1.9 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator DUF1116 PF06545.11 RLN92090.1 - 0.058 12.9 0.8 1.1 8.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1116) DivIC PF04977.15 RLN92090.1 - 0.076 12.8 0.4 0.076 12.8 0.4 3.5 4 0 0 4 4 4 0 Septum formation initiator ABC_tran_CTD PF16326.5 RLN92090.1 - 0.088 13.1 0.3 0.088 13.1 0.3 3.9 4 1 0 4 4 4 0 ABC transporter C-terminal domain MbeD_MobD PF04899.12 RLN92090.1 - 0.089 12.9 0.1 0.089 12.9 0.1 3.8 4 1 0 4 4 3 0 MbeD/MobD like DUF2046 PF09755.9 RLN92090.1 - 0.099 11.9 7.4 0.17 11.1 3.4 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DUF1664 PF07889.12 RLN92090.1 - 0.18 11.9 0.4 1 9.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TSC22 PF01166.18 RLN92090.1 - 0.2 12.0 3.4 1.5 9.2 0.0 3.6 4 0 0 4 4 4 0 TSC-22/dip/bun family FlaC_arch PF05377.11 RLN92090.1 - 0.2 12.1 0.1 60 4.1 0.0 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF3138 PF11336.8 RLN92090.1 - 0.22 10.1 3.2 0.21 10.1 1.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Nup54 PF13874.6 RLN92090.1 - 0.24 11.5 8.9 0.17 12.0 2.3 2.7 3 1 0 3 3 3 0 Nucleoporin complex subunit 54 DUF4407 PF14362.6 RLN92090.1 - 0.29 10.4 10.3 0.47 9.8 10.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1192 PF06698.11 RLN92090.1 - 0.32 11.1 6.9 3.6 7.7 0.9 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) GAS PF13851.6 RLN92090.1 - 0.99 8.7 5.9 0.31 10.4 0.9 2.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Myb_DNA-binding PF00249.31 RLN92091.1 - 0.00039 20.6 0.0 0.00097 19.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN92091.1 - 0.0074 16.2 0.0 0.025 14.5 0.0 1.9 1 0 0 1 1 1 1 Myb DNA-binding like AA_permease_C PF13906.6 RLN92092.1 - 5.5e-12 45.6 3.7 5.5e-12 45.6 3.7 2.6 2 0 0 2 2 2 1 C-terminus of AA_permease DUF5413 PF17434.2 RLN92092.1 - 0.028 14.7 2.8 0.052 13.9 2.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5413) DUF2417 PF10329.9 RLN92092.1 - 0.069 12.6 6.3 0.039 13.4 4.5 1.4 1 1 0 1 1 1 0 Region of unknown function (DUF2417) LRR19-TM PF15176.6 RLN92092.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF4713 PF15831.5 RLN92092.1 - 0.22 12.0 0.5 0.22 12.0 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) TctB PF07331.11 RLN92092.1 - 1.2 9.4 12.9 3.3 8.0 12.9 1.8 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF4728 PF15860.5 RLN92092.1 - 1.4 9.6 7.4 0.38 11.5 3.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4728) DUF3792 PF12670.7 RLN92092.1 - 4.9 7.3 12.4 1.2 9.3 5.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) Kinesin PF00225.23 RLN92093.1 - 8e-62 209.1 0.0 4e-34 118.0 0.0 2.0 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 RLN92093.1 - 1.9e-14 53.9 0.0 4.1e-14 52.8 0.0 1.5 2 0 0 2 2 2 1 Microtubule binding PLU-1 PF08429.11 RLN92095.1 - 3.1e-19 69.3 18.2 3.3e-16 59.4 9.0 4.8 1 1 1 2 2 2 2 PLU-1-like protein ELM2 PF01448.24 RLN92095.1 - 5.9e-06 26.9 1.8 3.4e-05 24.5 0.0 3.2 4 0 0 4 4 4 1 ELM2 domain IL32 PF15225.6 RLN92095.1 - 0.79 10.1 3.4 1.3 9.4 0.8 2.6 2 0 0 2 2 2 0 Interleukin 32 EF-hand_7 PF13499.6 RLN92096.1 - 2.6e-14 53.4 3.2 7e-14 52.0 3.2 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN92096.1 - 1.3e-13 49.4 3.3 1.3e-06 27.5 0.2 3.1 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 RLN92096.1 - 5.3e-12 44.7 6.2 3.5e-05 23.1 0.1 3.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RLN92096.1 - 1.1e-11 43.6 3.6 2.5e-05 23.9 0.0 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 RLN92096.1 - 2.3e-08 33.8 2.2 7.8e-08 32.1 0.8 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 RLN92096.1 - 2.6e-06 27.3 0.1 7.6e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 RLN92096.1 - 0.0013 19.0 0.2 0.003 17.8 0.2 1.5 1 0 0 1 1 1 1 EF-hand domain VbhA PF18495.1 RLN92096.1 - 0.035 14.0 0.7 0.73 9.7 0.1 3.0 3 0 0 3 3 3 0 Antitoxin VbhA DUF866 PF05907.13 RLN92096.1 - 0.15 11.9 2.0 0.31 10.9 2.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) AATase PF07247.12 RLN92098.1 - 8.1e-06 24.7 0.0 1.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Alcohol acetyltransferase ABC2_membrane_3 PF12698.7 RLN92099.1 - 4.7e-22 78.6 32.1 3.9e-21 75.5 32.1 2.0 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 RLN92099.1 - 0.00032 20.3 17.0 0.00032 20.3 17.0 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 RLN92099.1 - 0.0009 18.7 23.7 0.0024 17.3 19.2 2.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_2 PF12679.7 RLN92099.1 - 7.3 5.8 25.1 1.2 8.3 20.4 1.9 2 1 0 2 2 2 0 ABC-2 family transporter protein GTP_EFTU PF00009.27 RLN92100.1 - 9.3e-30 103.6 0.2 2.4e-29 102.3 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 RLN92100.1 - 1.8e-21 76.3 1.1 5.7e-21 74.6 0.3 2.2 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 RLN92100.1 - 0.00058 19.9 0.0 0.0015 18.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 RLN92100.1 - 0.026 14.3 0.0 0.1 12.4 0.0 1.9 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 RLN92100.1 - 0.027 14.4 0.1 0.078 12.9 0.0 1.8 1 1 1 2 2 2 0 RsgA GTPase GTP_EFTU_D2 PF03144.25 RLN92100.1 - 0.03 14.7 5.2 0.059 13.8 0.0 3.5 4 0 0 4 4 4 0 Elongation factor Tu domain 2 GCH_III PF05165.12 RLN92100.1 - 0.058 12.7 1.8 0.074 12.3 0.4 1.8 2 0 0 2 2 2 0 GTP cyclohydrolase III cNMP_binding PF00027.29 RLN92101.1 - 5e-13 48.9 0.1 1e-12 47.9 0.1 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CDC13_N PF16853.5 RLN92102.1 - 0.015 14.8 0.2 0.021 14.3 0.2 1.1 1 0 0 1 1 1 0 Cell division control protein 13 N-terminus Comm PF15957.5 RLN92102.1 - 0.015 15.6 0.5 0.032 14.6 0.5 1.5 1 1 0 1 1 1 0 Commissureless Cnn_1N PF07989.11 RLN92103.1 - 0.00092 19.3 1.7 0.0018 18.4 1.7 1.4 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 Shugoshin_N PF07558.11 RLN92103.1 - 0.0027 17.5 0.6 0.02 14.8 0.0 2.5 3 0 0 3 3 3 1 Shugoshin N-terminal coiled-coil region ATG16 PF08614.11 RLN92103.1 - 0.0071 16.6 0.5 0.01 16.1 0.5 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ADIP PF11559.8 RLN92103.1 - 0.023 14.8 0.9 0.023 14.8 0.9 1.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF5431 PF17496.2 RLN92103.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5431) GrpE PF01025.19 RLN92103.1 - 1 9.0 4.5 0.37 10.5 1.6 1.6 2 0 0 2 2 2 0 GrpE Kinesin PF00225.23 RLN92104.1 - 1.6e-77 260.7 0.6 1.6e-77 260.7 0.6 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RLN92104.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Microtubule binding bZIP_1 PF00170.21 RLN92104.1 - 0.014 15.5 2.2 0.058 13.5 1.2 2.5 2 0 0 2 2 2 0 bZIP transcription factor YabA PF06156.13 RLN92104.1 - 0.11 13.2 5.7 0.058 14.0 0.7 2.8 3 0 0 3 3 3 0 Initiation control protein YabA THOC7 PF05615.13 RLN92104.1 - 0.11 12.8 10.3 0.75 10.1 2.2 2.8 2 0 0 2 2 2 0 Tho complex subunit 7 DivIC PF04977.15 RLN92104.1 - 0.2 11.4 12.5 0.14 11.9 1.7 2.9 2 0 0 2 2 2 0 Septum formation initiator DUF5082 PF16888.5 RLN92104.1 - 0.79 10.0 8.4 0.068 13.5 2.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF3450 PF11932.8 RLN92104.1 - 0.8 9.0 12.1 0.54 9.5 3.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4140 PF13600.6 RLN92104.1 - 8.8 6.8 10.6 9.6 6.7 1.9 3.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Exo_endo_phos PF03372.23 RLN92105.1 - 3e-13 49.8 0.1 4.5e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ANAPC4_WD40 PF12894.7 RLN92106.1 - 2e-09 37.6 0.0 0.0045 17.2 0.0 3.3 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RLN92106.1 - 1.4e-05 25.8 0.7 0.025 15.4 0.0 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Nbas_N PF15492.6 RLN92106.1 - 0.0013 18.2 0.1 0.54 9.5 0.0 2.2 1 1 1 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Arf PF00025.21 RLN92107.1 - 1.3e-63 213.6 0.0 1.6e-63 213.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RLN92107.1 - 1.2e-13 51.4 0.0 1.7e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 RLN92107.1 - 1.3e-11 44.3 0.5 1.4e-07 31.0 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 RLN92107.1 - 4.3e-10 39.4 0.0 5e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 RLN92107.1 - 2.4e-09 36.9 0.0 2.8e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 RLN92107.1 - 5.9e-07 29.1 0.0 8.6e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RLN92107.1 - 0.00014 21.9 0.0 0.00022 21.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 RLN92107.1 - 0.00021 21.2 0.2 0.16 11.9 0.0 2.1 2 0 0 2 2 2 2 NACHT domain SRP54 PF00448.22 RLN92107.1 - 0.015 14.9 0.2 0.039 13.6 0.1 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 RLN92107.1 - 0.018 15.3 0.9 0.74 10.1 0.9 2.3 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RLN92107.1 - 0.021 14.5 0.1 0.039 13.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 RLN92107.1 - 0.024 14.2 1.0 5.6 6.5 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Optomotor-blind PF11078.8 RLN92109.1 - 0.23 12.1 3.1 0.63 10.6 0.0 3.1 4 0 0 4 4 4 0 Optomotor-blind protein N-terminal region FA_desaturase PF00487.24 RLN92111.1 - 9.5e-12 45.3 21.5 9.5e-12 45.3 21.5 1.6 1 1 1 2 2 2 2 Fatty acid desaturase HicA_toxin PF07927.12 RLN92112.1 - 0.044 13.8 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 HicA toxin of bacterial toxin-antitoxin, Csm1_N PF18504.1 RLN92113.1 - 0.3 11.4 3.4 2.3 8.6 0.5 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain Csm1_N PF18504.1 RLN92114.1 - 0.83 10.0 8.4 3.4 8.1 1.1 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain MPDZ_u10 PF16667.5 RLN92115.1 - 0.0084 17.0 0.6 4.7 8.2 0.2 2.6 2 0 0 2 2 2 2 Unstructured region 10 on multiple PDZ protein Lzipper-MIP1 PF14389.6 RLN92115.1 - 0.021 15.1 20.1 0.7 10.2 2.2 4.0 4 0 0 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 Fcf2 PF08698.11 RLN92115.1 - 0.43 11.0 7.5 11 6.5 0.3 3.3 3 0 0 3 3 3 0 Fcf2 pre-rRNA processing FMN_red PF03358.15 RLN92116.1 - 2.8e-19 69.4 0.0 8.7e-10 38.6 0.0 2.2 2 0 0 2 2 2 2 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 RLN92116.1 - 1.1e-09 38.4 0.0 9.4e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Flavodoxin-like fold Flavodoxin_1 PF00258.25 RLN92116.1 - 5.8e-05 23.3 0.0 0.22 11.7 0.0 2.6 2 1 0 2 2 2 2 Flavodoxin Bombesin PF02044.17 RLN92116.1 - 2.3 8.5 10.4 1.2 9.3 0.5 2.9 3 0 0 3 3 3 0 Bombesin-like peptide TauD PF02668.16 RLN92117.1 - 9.7e-39 133.8 0.0 1.6e-38 133.1 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 RLN92117.1 - 2.3e-16 60.2 0.1 4.4e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 RLN92117.1 - 0.0085 15.2 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 CsiD MFS_1 PF07690.16 RLN92118.1 - 3.6e-17 62.3 12.2 4.9e-17 61.9 12.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Nuc_H_symport PF03825.16 RLN92118.1 - 3.2e-06 26.4 5.6 0.0029 16.7 1.4 2.1 2 0 0 2 2 2 2 Nucleoside H+ symporter Sugar_tr PF00083.24 RLN92118.1 - 1.8e-05 23.8 9.7 6.1e-05 22.1 1.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_5 PF05631.14 RLN92118.1 - 0.001 18.1 0.6 0.002 17.1 0.6 1.5 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM DUF3481 PF11980.8 RLN92118.1 - 2.1 8.1 4.1 28 4.5 0.1 3.2 3 0 0 3 3 3 0 C-terminal domain of neuropilin glycoprotein DUF5336 PF17270.2 RLN92118.1 - 7.8 6.1 9.7 0.33 10.6 2.2 2.4 2 1 1 3 3 3 0 Family of unknown function (DUF5336) LRR_4 PF12799.7 RLN92119.1 - 0.00022 21.5 1.0 0.03 14.8 0.0 3.4 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN92119.1 - 0.00034 20.3 0.9 0.21 11.4 0.1 4.4 4 1 0 4 4 4 1 Leucine rich repeat DUF5455 PF17537.2 RLN92119.1 - 0.015 15.7 0.5 12 6.4 0.0 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5455) DUF3905 PF13045.6 RLN92119.1 - 0.19 11.8 1.2 26 4.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3905) ABC_membrane PF00664.23 RLN92120.1 - 2.7e-100 335.5 24.0 2.8e-57 194.5 1.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN92120.1 - 1.5e-61 206.9 0.0 1e-35 123.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN92120.1 - 9.2e-12 44.9 0.1 0.00016 21.2 0.0 3.3 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 RLN92120.1 - 2.2e-06 26.7 0.7 0.047 12.5 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 RLN92120.1 - 3.3e-06 27.6 1.1 0.0017 18.8 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 RLN92120.1 - 4.5e-06 27.1 0.0 0.0068 16.8 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 RLN92120.1 - 8.1e-06 25.5 0.2 0.0075 16.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN92120.1 - 1.1e-05 25.8 0.2 0.12 12.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN92120.1 - 1.6e-05 24.3 0.0 0.019 14.2 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 RLN92120.1 - 6.4e-05 22.9 0.0 0.018 15.0 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 RLN92120.1 - 8.3e-05 22.4 0.9 0.24 11.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain APS_kinase PF01583.20 RLN92120.1 - 9.7e-05 22.3 0.1 0.08 12.8 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_25 PF13481.6 RLN92120.1 - 0.0011 18.6 0.5 0.21 11.1 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 RLN92120.1 - 0.002 17.9 0.0 0.042 13.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain G-alpha PF00503.20 RLN92120.1 - 0.0084 15.3 0.0 0.56 9.3 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_5 PF07728.14 RLN92120.1 - 0.01 15.8 0.1 0.33 11.0 0.0 3.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 RLN92120.1 - 0.015 15.6 3.1 5.8 7.2 0.4 3.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 RLN92120.1 - 0.053 13.7 0.0 1.6 8.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 RLN92120.1 - 0.074 12.6 0.0 0.8 9.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_21 PF13304.6 RLN92120.1 - 0.082 12.7 0.1 1.3 8.7 0.0 2.8 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 RLN92120.1 - 0.089 13.3 0.0 0.61 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 RLN92120.1 - 0.19 11.7 0.1 17 5.3 0.0 3.1 3 0 0 3 3 3 0 NTPase Swi5 PF07061.11 RLN92122.1 - 0.048 13.8 1.4 0.11 12.5 0.1 2.1 2 0 0 2 2 2 0 Swi5 CCDC23 PF15674.5 RLN92122.1 - 0.28 11.2 2.1 6.2 6.9 0.1 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 23 bZIP_1 PF00170.21 RLN92122.1 - 9.9 6.4 11.3 0.24 11.5 0.5 2.6 2 1 0 2 2 2 0 bZIP transcription factor DUF4337 PF14235.6 RLN92123.1 - 0.066 13.3 0.4 0.12 12.5 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Spem1 PF15670.5 RLN92123.1 - 0.079 12.5 1.6 0.12 11.9 1.6 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 MRP-L28 PF09812.9 RLN92124.1 - 0.31 11.2 15.8 1.1 9.4 6.6 2.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 Dishevelled PF02377.15 RLN92124.1 - 1.9 8.9 6.6 9.1 6.7 0.1 2.8 3 0 0 3 3 3 0 Dishevelled specific domain MFS_1 PF07690.16 RLN92125.1 - 6.9e-20 71.3 24.3 1.1e-19 70.6 24.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN92125.1 - 7.3e-05 21.8 17.3 0.00012 21.1 8.9 2.6 1 1 1 2 2 2 2 Sugar (and other) transporter Nuc_H_symport PF03825.16 RLN92125.1 - 0.00016 20.8 8.5 0.0037 16.3 0.8 2.4 2 1 0 2 2 2 2 Nucleoside H+ symporter MFS_1_like PF12832.7 RLN92125.1 - 0.00046 19.1 10.0 0.0018 17.2 0.2 2.8 1 1 2 3 3 3 2 MFS_1 like family MFS_5 PF05631.14 RLN92125.1 - 0.0064 15.5 4.9 0.018 14.0 4.9 1.9 1 1 0 1 1 1 1 Sugar-tranasporters, 12 TM DUF3792 PF12670.7 RLN92125.1 - 4.6 7.4 18.5 0.67 10.1 2.3 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3792) E1-E2_ATPase PF00122.20 RLN92126.1 - 2e-31 108.9 0.0 8.2e-31 106.9 0.0 2.2 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 RLN92126.1 - 1e-08 35.8 0.0 7.9e-07 29.6 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RLN92126.1 - 1.5e-06 27.8 0.0 6.7e-06 25.7 0.0 2.2 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus EF-hand_6 PF13405.6 RLN92126.1 - 4.4e-05 23.1 1.2 3.2 7.9 0.0 6.3 6 0 0 6 6 6 1 EF-hand domain EF-hand_7 PF13499.6 RLN92126.1 - 0.00012 22.4 0.3 7.4 7.1 0.1 5.3 5 0 0 5 5 5 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN92126.1 - 0.00013 21.2 0.2 0.57 9.9 0.0 4.6 4 0 0 4 4 4 1 EF hand Cation_ATPase PF13246.6 RLN92126.1 - 0.023 14.8 0.0 0.086 12.9 0.0 2.0 2 0 0 2 2 2 0 Cation transport ATPase (P-type) Cys_rich_VLP PF14194.6 RLN92126.1 - 0.061 13.4 0.3 8.6 6.6 0.0 3.2 2 0 0 2 2 2 0 Cysteine-rich VLP HTH_Tnp_Tc5 PF03221.16 RLN92128.1 - 8.8e-10 38.5 0.8 3.1e-09 36.7 0.1 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_24 PF13412.6 RLN92128.1 - 0.028 14.0 0.0 0.068 12.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding RNase_H2_suC PF08615.11 RLN92128.1 - 0.034 14.3 0.8 0.5 10.5 0.3 2.5 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Utp14 PF04615.13 RLN92128.1 - 0.14 10.7 34.5 0.0081 14.8 8.5 2.2 2 0 0 2 2 2 0 Utp14 protein TFIIA PF03153.13 RLN92128.1 - 0.5 10.3 27.2 0.19 11.7 8.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF5320 PF17253.2 RLN92128.1 - 6.1 8.0 5.4 6.1 8.0 1.5 3.1 2 1 0 2 2 2 0 Family of unknown function (DUF5320) C12orf66_like PF09404.10 RLN92129.1 - 8.9e-18 64.3 5.0 1.1e-08 34.3 0.2 3.2 3 0 0 3 3 3 3 KICSTOR complex C12orf66 like ORC6 PF05460.13 RLN92129.1 - 0.11 11.8 1.4 0.19 10.9 1.4 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) dCache_1 PF02743.18 RLN92131.1 - 0.39 10.5 3.2 0.72 9.6 3.2 1.4 1 0 0 1 1 1 0 Cache domain Fez1 PF06818.15 RLN92131.1 - 0.82 10.1 38.2 2.9 8.3 7.6 2.8 2 1 0 2 2 2 0 Fez1 DNApol_Exo PF18136.1 RLN92131.1 - 2.5 7.1 8.4 0.12 11.5 2.3 1.7 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain CLTH PF10607.9 RLN92132.1 - 7.2e-29 100.6 0.5 4.4e-28 98.0 0.0 2.3 3 0 0 3 3 3 1 CTLH/CRA C-terminal to LisH motif domain DUF1682 PF07946.14 RLN92132.1 - 0.00031 20.0 0.5 0.00031 20.0 0.5 3.1 3 1 1 4 4 4 2 Protein of unknown function (DUF1682) DUF3929 PF13066.6 RLN92132.1 - 0.15 12.1 0.0 12 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3929) LRAT PF04970.13 RLN92134.1 - 7.8e-20 71.5 0.0 6e-19 68.6 0.0 2.3 1 1 0 1 1 1 1 Lecithin retinol acyltransferase zf-C3HC4_3 PF13920.6 RLN92134.1 - 1.1e-08 34.8 3.0 2.3e-08 33.8 3.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN92134.1 - 1.9e-06 28.1 4.5 4.4e-06 26.9 4.5 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 RLN92134.1 - 4.6e-05 23.2 3.5 0.00013 21.8 3.5 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 RLN92134.1 - 0.00015 21.5 4.9 0.0003 20.5 4.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN92134.1 - 0.00024 21.0 5.5 0.00024 21.0 5.5 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RLN92134.1 - 0.0039 17.0 4.1 0.0082 16.0 4.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Romo1 PF10247.9 RLN92134.1 - 0.0073 16.7 5.2 0.015 15.6 5.2 1.6 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 NLPC_P60 PF00877.19 RLN92134.1 - 0.021 14.9 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 NlpC/P60 family WES_acyltransf PF03007.16 RLN92134.1 - 0.033 13.9 0.3 0.071 12.9 0.2 1.6 1 1 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain zf-RING_UBOX PF13445.6 RLN92134.1 - 0.066 13.2 2.7 0.13 12.3 2.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Rick_17kDa_Anti PF05433.15 RLN92134.1 - 0.076 12.9 14.5 0.17 11.8 14.5 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain FANCL_C PF11793.8 RLN92134.1 - 0.36 11.0 6.7 18 5.6 6.7 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 RLN92134.1 - 0.47 10.3 6.3 1.5 8.6 6.3 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 RLN92134.1 - 0.48 10.6 6.9 1.2 9.3 6.9 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Evr1_Alr PF04777.13 RLN92134.1 - 1.9 9.0 5.8 1.3 9.6 0.5 2.5 1 1 1 2 2 2 0 Erv1 / Alr family zf-C2H2_11 PF16622.5 RLN92134.1 - 4.5 7.1 6.7 18 5.2 0.2 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type Ribosomal_60s PF00428.19 RLN92134.1 - 8.6 7.0 9.3 5.3 7.7 0.3 2.7 3 0 0 3 3 2 0 60s Acidic ribosomal protein ABC_tran PF00005.27 RLN92135.1 - 1.4e-20 74.3 0.0 1.9e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN92135.1 - 2.9e-05 23.6 0.3 0.033 13.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 RLN92135.1 - 3.4e-05 23.6 0.1 0.16 11.7 0.0 2.2 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_21 PF13304.6 RLN92135.1 - 0.00019 21.4 0.3 0.27 11.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 RLN92135.1 - 0.014 15.4 0.6 0.037 14.1 0.1 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 RLN92135.1 - 0.015 15.5 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 RLN92135.1 - 0.02 15.0 0.3 0.035 14.2 0.3 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain Dynamin_N PF00350.23 RLN92135.1 - 0.022 14.8 0.1 0.035 14.2 0.1 1.3 1 0 0 1 1 1 0 Dynamin family AAA_5 PF07728.14 RLN92135.1 - 0.14 12.1 0.3 10 6.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RLN92135.1 - 0.17 12.3 2.0 0.47 10.8 1.9 1.9 1 1 0 1 1 1 0 AAA ATPase domain Csd3_N PF18059.1 RLN92136.1 - 0.015 15.8 0.4 0.022 15.3 0.4 1.5 1 1 0 1 1 1 0 Csd3 N-terminal GTP_EFTU PF00009.27 RLN92137.1 - 5.4e-10 39.1 0.1 6.1e-10 38.9 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SKN1 PF03935.15 RLN92138.1 - 1.2e-73 248.2 1.4 1.9e-73 247.6 1.4 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) FKS1_dom1 PF14288.6 RLN92138.1 - 1.1e-20 74.3 2.8 1.7e-19 70.4 2.8 2.4 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF4203 PF13886.6 RLN92138.1 - 9.6e-08 31.9 20.5 9.6e-08 31.9 20.5 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4203) Serglycin PF04360.12 RLN92139.1 - 0.0058 16.6 2.6 0.0058 16.6 2.6 3.4 3 0 0 3 3 3 1 Serglycin LVIVD PF08309.11 RLN92139.1 - 0.034 13.5 0.1 0.11 11.9 0.1 1.8 1 0 0 1 1 1 0 LVIVD repeat BATS PF06968.13 RLN92140.1 - 1.1e-18 67.1 0.3 1.3e-17 63.7 0.1 2.4 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 RLN92140.1 - 9e-14 52.2 0.7 1.4e-13 51.5 0.7 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Peptidase_M24 PF00557.24 RLN92140.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Metallopeptidase family M24 PEP_hydrolase PF09370.10 RLN92140.1 - 0.071 12.3 0.2 2.2 7.4 0.1 2.2 2 0 0 2 2 2 0 Phosphoenolpyruvate hydrolase-like PhoLip_ATPase_C PF16212.5 RLN92141.1 - 9.9e-68 228.6 18.9 9.9e-68 228.6 18.9 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RLN92141.1 - 4.2e-17 61.6 2.3 4.2e-17 61.6 2.3 2.2 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 RLN92141.1 - 1.5e-11 44.3 0.0 5e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RLN92141.1 - 2e-08 34.8 5.1 3.6e-05 24.2 1.5 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RLN92141.1 - 8e-07 28.7 0.0 5.5e-06 26.0 0.0 2.5 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RLN92141.1 - 0.0062 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SURF2 PF05477.11 RLN92142.1 - 4.2e-38 131.4 26.1 3.7e-37 128.3 26.1 1.9 1 1 0 1 1 1 1 Surfeit locus protein 2 (SURF2) Nop14 PF04147.12 RLN92142.1 - 3.1 5.9 28.3 3.6 5.7 28.3 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RLN92142.1 - 3.2 5.9 17.7 4.1 5.6 17.7 1.2 1 0 0 1 1 1 0 CDC45-like protein COesterase PF00135.28 RLN92143.1 - 3.5e-60 204.3 1.6 7e-60 203.4 1.6 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RLN92143.1 - 0.018 14.9 0.4 0.14 12.0 0.4 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold ABC2_membrane PF01061.24 RLN92144.1 - 1.3e-51 175.0 52.7 5.5e-28 97.8 20.0 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 RLN92144.1 - 7.9e-15 55.6 0.0 2.8e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN92144.1 - 4.4e-09 36.6 0.3 0.0023 17.8 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 RLN92144.1 - 3.7e-07 29.6 38.4 0.0032 16.7 9.4 3.6 3 1 0 3 3 3 2 ABC-2 family transporter protein ABC2_membrane PF01061.24 RLN92145.1 - 3.6e-36 124.6 20.2 5.7e-36 123.9 20.2 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN92145.1 - 2.5e-26 92.8 0.0 4.2e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN92145.1 - 4e-09 36.7 0.0 0.0005 20.0 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN92145.1 - 0.00061 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN92145.1 - 0.0012 18.5 0.1 0.0027 17.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN92145.1 - 0.0022 18.4 0.0 0.004 17.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 RLN92145.1 - 0.0051 17.3 0.0 0.0096 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 RLN92145.1 - 0.0056 16.1 1.0 0.8 9.1 0.2 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RLN92145.1 - 0.011 16.0 0.0 0.45 10.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 RLN92145.1 - 0.11 11.6 17.7 0.17 10.9 17.7 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1462 PF07315.11 RLN92145.1 - 0.17 12.2 0.0 2.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1462) ABC2_membrane PF01061.24 RLN92146.1 - 1.6e-41 142.0 18.1 2.6e-41 141.4 18.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN92146.1 - 1e-27 97.3 0.1 1.9e-27 96.5 0.0 1.5 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 RLN92146.1 - 9.9e-09 35.4 0.1 0.00049 20.0 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN92146.1 - 0.00051 20.0 0.0 0.00094 19.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN92146.1 - 0.0013 18.4 0.2 0.0029 17.3 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3902 PF13042.6 RLN92146.1 - 0.0016 18.1 0.6 0.004 16.7 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3902) AAA_16 PF13191.6 RLN92146.1 - 0.0021 18.4 0.0 0.0036 17.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 RLN92146.1 - 0.0049 16.3 1.1 0.82 9.1 0.2 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RLN92146.1 - 0.0055 17.2 0.0 0.0095 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RLN92146.1 - 0.011 16.0 0.0 0.25 11.6 0.1 2.4 1 1 1 2 2 2 0 AAA domain Rad17 PF03215.15 RLN92146.1 - 0.037 13.9 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain ABC2_membrane_3 PF12698.7 RLN92146.1 - 0.056 12.5 18.8 0.025 13.7 16.2 1.7 1 1 1 2 2 2 0 ABC-2 family transporter protein Glyco_hydro_3 PF00933.21 RLN92147.1 - 6.6e-07 29.0 0.0 8.5e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Elicitin PF00964.17 RLN92149.1 - 2.6e-14 53.1 0.2 2.6e-14 53.1 0.2 2.6 2 1 0 2 2 2 1 Elicitin MID_MedPIWI PF18296.1 RLN92149.1 - 0.39 10.5 8.6 0.45 10.3 8.6 1.2 1 0 0 1 1 1 0 MID domain of medPIWI SAPS PF04499.15 RLN92149.1 - 0.72 8.6 4.3 0.72 8.6 4.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HNF-1_N PF04814.13 RLN92149.1 - 0.84 10.2 10.5 1.1 9.8 10.5 1.3 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus RIFIN PF02009.16 RLN92149.1 - 0.99 9.2 5.6 0.96 9.3 5.6 1.1 1 0 0 1 1 1 0 Rifin FSA_C PF10479.9 RLN92149.1 - 1.2 7.2 25.1 1.3 7.0 25.1 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Plasmodium_Vir PF05795.11 RLN92149.1 - 1.4 8.2 4.8 1.3 8.3 4.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SWI-SNF_Ssr4 PF08549.10 RLN92149.1 - 2.1 6.9 9.1 2.3 6.7 9.1 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SpoIIIAH PF12685.7 RLN92149.1 - 6.5 6.5 16.1 8.8 6.1 16.1 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein PXB PF12828.7 RLN92150.1 - 0.0023 17.9 0.1 0.0043 17.1 0.1 1.4 1 0 0 1 1 1 1 PX-associated PIGA PF08288.12 RLN92151.1 - 1.4e-36 124.9 0.2 3.1e-36 123.8 0.2 1.6 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 RLN92151.1 - 7.1e-27 94.5 0.7 1.2e-26 93.8 0.7 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 RLN92151.1 - 9.9e-27 93.6 0.0 1.9e-26 92.6 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RLN92151.1 - 8.6e-24 84.5 0.2 1.5e-23 83.7 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 RLN92151.1 - 9.6e-13 48.9 1.1 9.6e-13 48.9 1.1 2.3 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 RLN92151.1 - 1e-05 25.8 0.0 1.8e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 ORC2 PF04084.14 RLN92151.1 - 0.23 10.4 0.0 0.43 9.4 0.0 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 2 Elicitin PF00964.17 RLN92152.1 - 3.3e-21 75.2 3.1 3.3e-21 75.2 3.1 2.0 2 0 0 2 2 2 1 Elicitin DUF3439 PF11921.8 RLN92152.1 - 0.77 9.7 17.4 0.039 13.9 10.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 RLN92152.1 - 5.2 4.9 5.0 7 4.5 5.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Elicitin PF00964.17 RLN92153.1 - 7.4e-22 77.3 1.2 1.4e-21 76.3 1.2 1.5 1 0 0 1 1 1 1 Elicitin PT PF04886.12 RLN92153.1 - 3.1e-05 23.4 62.8 0.0009 18.7 26.3 2.7 1 1 1 2 2 2 2 PT repeat Elicitin PF00964.17 RLN92155.1 - 2.7e-14 53.0 0.2 2.7e-14 53.0 0.2 2.6 2 1 0 2 2 2 1 Elicitin MID_MedPIWI PF18296.1 RLN92155.1 - 0.4 10.4 8.4 0.49 10.1 8.4 1.3 1 0 0 1 1 1 0 MID domain of medPIWI RIFIN PF02009.16 RLN92155.1 - 0.92 9.3 6.3 0.99 9.2 6.3 1.1 1 0 0 1 1 1 0 Rifin Plasmodium_Vir PF05795.11 RLN92155.1 - 1.5 8.1 5.2 1.4 8.2 5.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SWI-SNF_Ssr4 PF08549.10 RLN92155.1 - 4 6.0 10.0 4.4 5.8 10.0 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Elicitin PF00964.17 RLN92156.1 - 2.1e-15 56.6 0.3 2.3e-15 56.5 0.3 1.0 1 0 0 1 1 1 1 Elicitin Ribosomal_60s PF00428.19 RLN92157.1 - 2 9.1 11.6 1.8 9.2 7.1 2.3 1 1 1 2 2 2 0 60s Acidic ribosomal protein DNA_pol_A_exo1 PF01612.20 RLN92158.1 - 2.3e-19 69.8 0.0 5e-19 68.7 0.0 1.5 2 0 0 2 2 2 1 3'-5' exonuclease HpaB_N PF11794.8 RLN92158.1 - 0.011 15.5 0.1 0.017 14.8 0.1 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Pkinase PF00069.25 RLN92160.1 - 1.7e-21 76.8 0.0 2.3e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92160.1 - 2e-11 43.7 0.0 2.8e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN92160.1 - 4e-05 23.6 0.1 0.25 11.2 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 RLN92160.1 - 0.0013 18.1 0.0 0.0076 15.6 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN92160.1 - 0.013 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 RLN92160.1 - 0.083 11.7 0.0 0.21 10.3 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase DUF416 PF04222.12 RLN92160.1 - 0.085 12.3 0.2 1.7 8.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF416) Vac14_Fab1_bd PF12755.7 RLN92161.1 - 0.00046 20.7 0.0 0.0008 20.0 0.0 1.3 1 1 0 1 1 1 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 RLN92161.1 - 0.0061 16.7 1.2 0.16 12.3 0.2 3.1 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 RLN92161.1 - 0.028 15.0 0.4 0.12 13.0 0.2 2.3 1 1 0 1 1 1 0 HEAT-like repeat MMS19_N PF14500.6 RLN92161.1 - 0.032 13.8 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Dopey_N PF04118.14 RLN92161.1 - 0.054 12.6 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 Dopey, N-terminal MMS19_C PF12460.8 RLN92161.1 - 0.07 12.2 0.1 0.091 11.9 0.1 1.2 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal ELMO_CED12 PF04727.13 RLN92162.1 - 4.6e-23 82.2 0.0 5.5e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 ELMO/CED-12 family zf-C2H2_jaz PF12171.8 RLN92163.1 - 7.1e-09 35.7 0.2 1.4e-08 34.8 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 RLN92163.1 - 0.099 13.3 0.1 0.17 12.6 0.0 1.4 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 RLN92163.1 - 0.17 12.3 0.4 0.33 11.4 0.1 1.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Cript PF10235.9 RLN92164.1 - 1.3e-16 61.0 2.2 2.9e-16 59.8 2.2 1.7 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT C1_2 PF03107.16 RLN92164.1 - 0.0065 16.8 2.9 0.0065 16.8 2.9 1.8 2 0 0 2 2 2 1 C1 domain PHF5 PF03660.14 RLN92164.1 - 0.01 16.0 0.9 0.01 16.0 0.9 1.8 2 0 0 2 2 2 0 PHF5-like protein DZR PF12773.7 RLN92164.1 - 0.034 14.2 4.6 0.096 12.7 4.6 1.7 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 RLN92164.1 - 0.15 12.8 6.7 0.58 11.0 6.7 2.0 1 1 0 1 1 1 0 zinc-ribbon family C1_1 PF00130.22 RLN92164.1 - 0.26 11.2 3.7 0.59 10.1 1.3 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.25 RLN92165.1 - 2.8e-26 92.5 0.0 4.3e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92165.1 - 1.9e-15 56.9 0.0 2.4e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN92165.1 - 9.5e-09 34.5 0.0 1.4e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 RLN92165.1 - 0.0053 15.8 0.1 0.0082 15.2 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 RLN92165.1 - 0.023 14.6 0.0 0.11 12.4 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN92165.1 - 0.052 12.9 0.1 0.08 12.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 RLN92166.1 - 1.9e-24 86.5 0.0 4.4e-24 85.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92166.1 - 3.1e-13 49.6 0.0 3.5e-12 46.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN92166.1 - 2.1e-08 33.4 0.0 2.9e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 RLN92166.1 - 0.0051 15.9 0.1 0.0074 15.3 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 RLN92166.1 - 0.011 15.7 0.3 0.03 14.2 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Methyltransf_31 PF13847.6 RLN92167.1 - 5.5e-10 39.2 0.0 1.3e-07 31.5 0.0 2.1 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 RLN92167.1 - 2.2e-09 37.8 0.0 6.1e-08 33.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN92167.1 - 1.1e-08 35.6 0.1 6.2e-06 26.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN92167.1 - 1.2e-06 29.2 0.0 5.1e-05 23.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN92167.1 - 1.7e-06 28.0 0.0 2e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN92167.1 - 0.047 13.0 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DREV PF05219.12 RLN92167.1 - 0.064 12.3 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase CheR PF01739.18 RLN92167.1 - 0.067 12.7 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain DUF3850 PF12961.7 RLN92167.1 - 0.15 12.1 0.0 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3850) Cyclin PF08613.11 RLN92168.1 - 3.3e-16 60.1 0.4 4.8e-16 59.5 0.4 1.3 1 0 0 1 1 1 1 Cyclin p31comet PF06581.12 RLN92168.1 - 0.021 14.0 0.1 0.028 13.6 0.1 1.1 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding Cyclin_N PF00134.23 RLN92168.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Cyclin, N-terminal domain Ras PF00071.22 RLN92169.1 - 1.4e-54 184.0 2.1 6.2e-52 175.5 2.1 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RLN92169.1 - 2.3e-29 102.1 1.1 3.7e-18 65.9 0.1 2.8 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN92169.1 - 2.9e-12 46.4 0.4 2.4e-11 43.4 0.4 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RLN92169.1 - 3.4e-06 27.1 0.7 0.058 13.3 0.2 2.3 1 1 1 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 RLN92169.1 - 0.0072 15.9 0.0 0.22 11.0 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region GTP_EFTU PF00009.27 RLN92169.1 - 0.0073 15.9 0.2 0.017 14.6 0.1 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 RLN92169.1 - 0.011 16.2 0.2 2.1 8.8 0.0 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 RLN92169.1 - 0.012 15.7 0.1 1.3 9.2 0.1 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 RLN92169.1 - 0.019 14.4 0.1 0.36 10.2 0.0 2.1 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 RLN92169.1 - 0.025 14.8 0.0 0.039 14.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RLN92169.1 - 0.043 13.6 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN92169.1 - 0.045 14.1 0.0 0.064 13.6 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 RLN92169.1 - 0.051 13.6 0.1 0.12 12.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) FeoB_N PF02421.18 RLN92169.1 - 0.086 12.4 0.0 0.77 9.3 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B Gtr1_RagA PF04670.12 RLN92169.1 - 0.12 11.7 1.0 5.5 6.3 0.9 2.2 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region TniB PF05621.11 RLN92169.1 - 0.15 11.4 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein ABC_tran PF00005.27 RLN92169.1 - 0.17 12.4 0.0 0.26 11.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA PF00004.29 RLN92170.1 - 6.5e-17 62.2 0.0 1.4e-16 61.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 RLN92170.1 - 2.8e-13 50.0 0.0 5.1e-11 42.6 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 RLN92170.1 - 5.6e-11 42.7 0.0 1.5e-10 41.3 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA_24 PF13479.6 RLN92170.1 - 4.6e-06 26.5 0.0 1.8e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN92170.1 - 9.5e-06 26.1 1.0 0.00041 20.8 0.1 2.7 2 2 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 RLN92170.1 - 1.7e-05 24.6 0.0 0.00014 21.6 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 RLN92170.1 - 2.7e-05 24.4 0.0 0.00016 22.0 0.0 2.1 2 0 0 2 2 2 1 AAA C-terminal domain AAA_22 PF13401.6 RLN92170.1 - 7.6e-05 23.0 1.0 0.017 15.4 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 RLN92170.1 - 0.00026 20.8 0.0 0.00054 19.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 RLN92170.1 - 0.00073 19.0 0.0 0.058 12.8 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RLN92170.1 - 0.0018 18.1 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 RLN92170.1 - 0.0024 17.7 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit ResIII PF04851.15 RLN92170.1 - 0.0049 16.9 0.0 0.014 15.4 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RLN92170.1 - 0.0059 17.0 0.0 0.057 13.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 RLN92170.1 - 0.012 15.6 0.1 0.087 12.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 RLN92170.1 - 0.018 15.6 0.0 0.033 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 RLN92170.1 - 0.019 14.7 0.0 0.066 12.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 RLN92170.1 - 0.022 14.5 0.1 0.15 11.8 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase Sigma54_activat PF00158.26 RLN92170.1 - 0.023 14.4 0.0 0.16 11.6 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 RLN92170.1 - 0.049 13.1 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region TniB PF05621.11 RLN92170.1 - 0.066 12.6 0.0 11 5.4 0.0 3.0 3 0 0 3 3 3 0 Bacterial TniB protein NTPase_1 PF03266.15 RLN92170.1 - 0.091 12.7 0.2 17 5.3 0.1 2.9 2 1 1 3 3 3 0 NTPase PhoH PF02562.16 RLN92170.1 - 0.11 11.9 0.1 4.4 6.7 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DUF5338 PF17273.2 RLN92170.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5338) Lectin_leg-like PF03388.13 RLN92171.1 - 7.5e-32 110.5 0.1 1.1e-31 109.9 0.1 1.3 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 RLN92171.1 - 1.4e-12 48.0 1.5 2.7e-12 47.1 1.5 1.4 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 RLN92171.1 - 5.2e-09 36.0 0.1 1.6e-08 34.4 0.1 1.8 1 1 0 1 1 1 1 Legume lectin domain Ead_Ea22 PF13935.6 RLN92171.1 - 0.0017 19.1 8.5 0.35 11.5 4.7 2.4 1 1 1 2 2 2 2 Ead/Ea22-like protein DUF445 PF04286.12 RLN92171.1 - 0.007 16.2 3.6 0.0089 15.9 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Phage_tail_NK PF16532.5 RLN92171.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales Grg1 PF11034.8 RLN92171.1 - 0.18 12.0 3.2 0.39 11.0 3.2 1.5 1 0 0 1 1 1 0 Glucose-repressible protein Grg1 MscS_porin PF12795.7 RLN92171.1 - 2.2 7.8 11.2 1.4 8.4 7.9 2.0 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Sigma70_ner PF04546.13 RLN92171.1 - 3 7.7 10.5 6.8 6.5 10.5 1.5 1 1 0 1 1 1 0 Sigma-70, non-essential region WD40 PF00400.32 RLN92173.1 - 1.3e-15 57.5 10.6 1.3e-05 25.9 0.3 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN92173.1 - 2.3e-07 31.0 1.3 0.04 14.2 0.0 4.5 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain His_Phos_2 PF00328.22 RLN92174.1 - 8.7e-18 64.8 0.0 2.8e-11 43.4 0.0 2.3 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Surfac_D-trimer PF09006.11 RLN92175.1 - 0.22 11.5 1.0 1.3 8.9 0.0 2.8 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Cyclin_N PF00134.23 RLN92176.1 - 5.7e-08 32.6 2.3 7.3e-06 25.7 0.1 2.4 1 1 1 2 2 2 2 Cyclin, N-terminal domain DUF2373 PF10180.9 RLN92177.1 - 4.2e-15 55.3 1.0 1.6e-12 47.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2373) EF-hand_7 PF13499.6 RLN92178.1 - 0.0002 21.7 2.5 0.015 15.8 0.6 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN92178.1 - 0.001 18.9 0.6 3 8.0 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 RLN92178.1 - 0.0022 17.4 0.1 3.8 7.3 0.0 3.2 3 0 0 3 3 3 2 EF hand SPC25 PF06703.11 RLN92178.1 - 1.2 8.9 6.8 15 5.3 0.1 2.5 2 1 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) PRCC PF10253.9 RLN92179.1 - 1.6 9.5 11.5 2 9.1 11.5 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SOG2 PF10428.9 RLN92179.1 - 8.3 5.5 16.6 8.7 5.4 16.6 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Guanylate_cyc PF00211.20 RLN92180.1 - 5.2e-12 45.8 0.0 1.1e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 RLN92181.1 - 7.8e-10 38.7 0.0 1.4e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Myb_DNA-bind_4 PF13837.6 RLN92182.1 - 6.2e-05 23.3 0.1 0.14 12.6 0.1 2.5 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 RLN92182.1 - 0.0022 18.0 0.1 2.8 8.1 0.1 2.8 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 RLN92182.1 - 0.06 13.7 0.4 0.48 10.8 0.1 2.5 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Guanylate_cyc PF00211.20 RLN92183.1 - 2.6e-12 46.7 0.0 4.9e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Presenilin PF01080.17 RLN92184.1 - 0.18 10.5 1.8 0.26 10.0 1.8 1.3 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 RLN92184.1 - 6.1 5.3 8.5 7.5 5.0 8.5 1.2 1 0 0 1 1 1 0 Macoilin family Guanylate_cyc PF00211.20 RLN92185.1 - 1.3e-10 41.2 0.1 2.9e-10 40.0 0.0 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain mTERF PF02536.14 RLN92187.1 - 1.7e-15 56.8 0.0 4.6e-15 55.4 0.0 1.7 1 1 0 1 1 1 1 mTERF Guanylate_cyc PF00211.20 RLN92188.1 - 2.5e-12 46.8 0.0 5.1e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF1467 PF07330.12 RLN92188.1 - 0.031 14.2 3.8 0.12 12.3 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1467) Exo70 PF03081.15 RLN92189.1 - 7.1e-07 28.6 0.1 0.005 15.9 0.0 3.0 2 1 1 3 3 3 2 Exo70 exocyst complex subunit Sec34 PF04136.15 RLN92189.1 - 0.00054 19.9 0.1 0.00091 19.1 0.1 1.4 1 0 0 1 1 1 1 Sec34-like family PAH PF02671.21 RLN92189.1 - 0.014 15.5 1.0 4.5 7.5 0.1 2.6 2 0 0 2 2 2 0 Paired amphipathic helix repeat SGL PF08450.12 RLN92190.1 - 3.7e-08 33.3 0.0 5e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 RLN92190.1 - 5.2e-05 23.1 1.5 0.4 10.8 0.0 4.3 5 0 0 5 5 5 2 NHL repeat Str_synth PF03088.16 RLN92190.1 - 0.011 15.8 0.0 0.39 10.9 0.0 2.3 2 0 0 2 2 2 0 Strictosidine synthase Arylesterase PF01731.20 RLN92190.1 - 0.044 14.0 0.0 0.43 10.8 0.0 2.3 3 0 0 3 3 3 0 Arylesterase Ldl_recept_b PF00058.17 RLN92190.1 - 0.15 12.6 0.0 1.4 9.5 0.0 2.4 3 0 0 3 3 3 0 Low-density lipoprotein receptor repeat class B ABC1 PF03109.16 RLN92191.1 - 5.1e-27 94.4 0.1 9.4e-27 93.6 0.1 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 RLN92191.1 - 0.039 13.3 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain RIO1 PF01163.22 RLN92191.1 - 0.088 12.4 0.0 0.22 11.1 0.0 1.7 1 1 0 1 1 1 0 RIO1 family APH PF01636.23 RLN92191.1 - 0.99 9.3 9.2 42 3.9 8.3 3.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1394 PF07159.12 RLN92192.1 - 1e-31 110.3 1.6 3.7e-24 85.5 0.3 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1394) DUF711 PF05167.12 RLN92192.1 - 0.003 16.5 0.2 0.0035 16.3 0.2 1.3 1 1 0 1 1 1 1 Uncharacterised ACR (DUF711) Methyltransf_23 PF13489.6 RLN92194.1 - 9.2e-14 51.6 0.0 1.5e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN92194.1 - 2.3e-09 37.9 0.0 2.2e-08 34.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN92194.1 - 4.2e-08 33.8 0.0 0.013 16.2 0.0 2.6 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 RLN92194.1 - 1.4e-05 24.9 0.0 0.011 15.6 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 RLN92194.1 - 2e-05 25.1 0.0 0.0007 20.2 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN92194.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain IU_nuc_hydro PF01156.19 RLN92195.1 - 5.9e-63 213.2 0.1 6.8e-63 213.0 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase PRA-PH PF01503.17 RLN92195.1 - 0.12 12.9 0.0 25 5.4 0.0 2.3 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Nuc_sug_transp PF04142.15 RLN92196.1 - 3.1e-26 92.3 5.9 7.9e-26 91.0 5.9 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 RLN92196.1 - 0.0001 22.5 11.9 0.00031 20.9 7.8 2.3 2 0 0 2 2 2 1 EamA-like transporter family UAA PF08449.11 RLN92196.1 - 0.00025 20.3 2.9 0.00045 19.5 2.9 1.5 1 1 0 1 1 1 1 UAA transporter family Musclin PF11037.8 RLN92196.1 - 0.0047 16.8 0.4 0.0075 16.2 0.4 1.3 1 0 0 1 1 1 1 Insulin-resistance promoting peptide in skeletal muscle DUF2809 PF10990.8 RLN92196.1 - 0.25 12.0 8.5 0.27 11.9 0.3 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2809) EF-hand_7 PF13499.6 RLN92199.1 - 1.5e-16 60.6 1.0 2.3e-07 31.2 0.1 2.9 1 1 1 2 2 2 2 EF-hand domain pair LRR_6 PF13516.6 RLN92199.1 - 3.3e-16 57.9 13.2 0.0036 17.2 0.0 8.4 8 0 0 8 8 8 5 Leucine Rich repeat EF-hand_6 PF13405.6 RLN92199.1 - 2.7e-15 54.9 0.3 0.012 15.4 0.0 4.8 3 1 1 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 RLN92199.1 - 1e-14 52.9 0.0 0.0068 15.9 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 RLN92199.1 - 6.1e-09 35.0 0.3 0.0046 16.4 0.0 4.4 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 RLN92199.1 - 1.7e-07 31.0 0.6 0.01 15.7 0.0 4.5 3 1 1 4 4 4 2 EF-hand domain pair LRR_4 PF12799.7 RLN92199.1 - 0.00012 22.4 0.1 7.7 7.1 0.0 3.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN92199.1 - 0.0069 16.8 0.1 3.5e+02 2.4 0.0 6.1 6 0 0 6 6 6 0 Leucine Rich Repeat Strep_pep PF14404.6 RLN92199.1 - 0.1 12.9 0.1 0.32 11.3 0.1 1.8 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Streptomyces species LRR_8 PF13855.6 RLN92199.1 - 7.3 6.4 12.4 4.4 7.1 0.3 5.1 4 3 0 4 4 4 0 Leucine rich repeat Phage_CI_C PF16452.5 RLN92200.1 - 4.9e-09 36.4 9.3 21 5.5 0.1 9.8 1 1 7 8 8 8 5 Bacteriophage CI repressor C-terminal domain PHA_gran_rgn PF09650.10 RLN92200.1 - 0.24 11.7 0.7 26 5.2 0.0 3.8 4 0 0 4 4 4 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) EF-hand_like PF09279.11 RLN92200.1 - 0.63 10.6 7.0 14 6.3 0.1 4.1 2 2 4 6 6 6 0 Phosphoinositide-specific phospholipase C, efhand-like CBM_1 PF00734.18 RLN92201.1 - 1.1e-07 31.7 18.9 1.7e-07 31.1 6.8 3.8 3 1 0 3 3 3 2 Fungal cellulose binding domain NAD_Gly3P_dh_C PF07479.14 RLN92202.1 - 6.1e-22 78.4 0.0 1.1e-21 77.6 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 2OG-FeII_Oxy_3 PF13640.6 RLN92202.1 - 6.5e-18 65.4 0.0 1.1e-17 64.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 RLN92202.1 - 2.8e-07 31.1 0.0 6.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Mannosyl_trans3 PF11051.8 RLN92203.1 - 3e-06 26.8 0.0 4.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative preSET_CXC PF18264.1 RLN92203.1 - 0.039 14.4 1.8 0.47 11.0 0.1 2.5 2 0 0 2 2 2 0 CXC domain C1_1 PF00130.22 RLN92205.1 - 0.079 12.9 3.8 0.16 11.9 3.8 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF92 PF01940.16 RLN92206.1 - 1.6e-73 247.0 6.7 1.9e-73 246.7 6.7 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 Bacteriocin_IIc PF10439.9 RLN92206.1 - 7.8 6.7 9.0 35 4.6 9.0 2.1 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Phage_holin_3_3 PF16083.5 RLN92206.1 - 8.4 6.6 11.5 0.13 12.4 2.3 2.7 3 1 0 4 4 4 0 LydA holin phage, holin superfamily III DUF92 PF01940.16 RLN92207.1 - 6.6e-75 251.6 8.9 7.7e-75 251.3 8.9 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 CCSMST1 PF15013.6 RLN92207.1 - 0.2 11.8 0.0 0.43 10.8 0.0 1.5 1 0 0 1 1 1 0 CCSMST1 family AA_permease_2 PF13520.6 RLN92208.1 - 6.9e-29 100.9 28.9 9.1e-29 100.5 28.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN92208.1 - 3.4e-17 62.2 26.5 4.5e-17 61.8 26.5 1.1 1 0 0 1 1 1 1 Amino acid permease FYVE_2 PF02318.16 RLN92209.1 - 0.21 11.8 8.4 0.5 10.6 8.4 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4_3 PF13920.6 RLN92209.1 - 1.2 9.0 18.5 0.65 9.9 9.9 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 RLN92210.1 - 0.002 18.3 0.2 0.0045 17.2 0.2 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 RLN92210.1 - 0.027 14.6 4.3 0.057 13.6 4.3 1.6 1 0 0 1 1 1 0 FYVE zinc finger Snurportin1 PF11538.8 RLN92210.1 - 0.11 12.7 4.3 0.054 13.7 1.5 2.0 2 0 0 2 2 2 0 Snurportin1 C1_1 PF00130.22 RLN92211.1 - 0.006 16.4 0.6 0.012 15.4 0.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF656 PF04920.12 RLN92211.1 - 0.025 14.5 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF656) DHC PF09626.10 RLN92211.1 - 0.027 15.3 1.4 0.037 14.9 0.2 1.7 2 0 0 2 2 2 0 Dihaem cytochrome c DUF4780 PF16012.5 RLN92211.1 - 0.087 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4780) PDZ PF00595.24 RLN92212.1 - 9.7e-08 32.3 0.0 2.6e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RLN92212.1 - 4.5e-07 29.6 0.0 1.2e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RLN92212.1 - 1.4e-06 28.5 0.1 8.5e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 PDZ domain VPS13_C PF16909.5 RLN92212.1 - 6.9e-05 22.7 0.0 0.00019 21.2 0.0 1.8 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal Tricorn_PDZ PF14685.6 RLN92212.1 - 0.0058 16.6 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 Tricorn protease PDZ domain SHR-BD PF06650.12 RLN92212.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 SHR-binding domain of vacuolar-sorting associated protein 13 IQ PF00612.27 RLN92213.1 - 0.0033 17.1 12.7 0.044 13.6 3.7 4.0 2 0 0 2 2 2 2 IQ calmodulin-binding motif UCH PF00443.29 RLN92214.1 - 2.1e-36 125.7 0.0 5.9e-36 124.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-RanBP PF00641.18 RLN92214.1 - 2.3e-20 71.6 40.4 1.1e-06 27.9 2.8 5.7 5 0 0 5 5 5 4 Zn-finger in Ran binding protein and others UCH_1 PF13423.6 RLN92214.1 - 5.4e-18 65.6 7.2 3.7e-10 39.9 0.1 3.5 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase Laminin_G_3 PF13385.6 RLN92214.1 - 1.8e-10 41.2 0.5 1.6e-09 38.1 0.0 2.8 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF2464 PF10240.9 RLN92214.1 - 9.5e-08 31.9 0.0 0.0025 17.5 0.0 3.6 3 0 0 3 3 3 2 Multivesicular body subunit 12 zf-UBR PF02207.20 RLN92214.1 - 0.002 18.3 12.2 0.002 18.3 12.2 6.1 6 1 1 7 7 7 1 Putative zinc finger in N-recognin (UBR box) PE PF00934.20 RLN92214.1 - 0.42 10.9 4.6 1.7 9.0 0.9 2.7 2 0 0 2 2 2 0 PE family LRR_4 PF12799.7 RLN92215.1 - 7.2e-11 42.2 0.3 0.0007 19.9 0.0 5.9 2 1 5 7 7 7 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RLN92215.1 - 5.2e-08 32.3 7.5 1.2 9.3 0.0 7.7 9 0 0 9 9 9 2 Leucine Rich repeat LRR_8 PF13855.6 RLN92215.1 - 0.0026 17.5 5.6 18 5.2 0.8 5.1 2 1 1 4 4 4 3 Leucine rich repeat F-box PF00646.33 RLN92215.1 - 0.0028 17.5 0.3 0.3 11.0 0.2 2.9 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 RLN92215.1 - 1.5 9.6 12.4 26 5.9 0.0 7.0 9 0 0 9 9 9 0 Leucine Rich Repeat Methyltransf_16 PF10294.9 RLN92216.1 - 1.2e-07 31.7 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 RLN92216.1 - 0.00013 22.6 0.0 0.00092 19.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 RLN92216.1 - 0.001 18.7 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 RLN92216.1 - 0.0054 17.4 0.0 0.02 15.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN92216.1 - 0.016 15.0 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 RLN92216.1 - 0.027 14.0 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 RLN92216.1 - 0.13 12.0 0.0 0.63 9.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 RLN92216.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) LisH PF08513.11 RLN92217.1 - 1.3e-06 28.1 0.2 6.8e-06 25.8 0.0 2.4 2 0 0 2 2 2 1 LisH Nop14 PF04147.12 RLN92217.1 - 1 7.5 22.9 0.47 8.6 20.1 1.7 2 0 0 2 2 2 0 Nop14-like family Ubie_methyltran PF01209.18 RLN92218.1 - 1.8e-83 279.4 0.0 2.3e-83 279.1 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 RLN92218.1 - 1.8e-18 67.0 0.1 5.3e-18 65.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN92218.1 - 4.3e-18 65.8 0.1 2.1e-17 63.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN92218.1 - 9.8e-13 48.7 0.0 1.9e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN92218.1 - 7.2e-12 45.3 0.0 1.2e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN92218.1 - 8.9e-09 35.4 0.0 1.2e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 RLN92218.1 - 0.0014 18.5 0.0 0.0057 16.5 0.0 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_32 PF13679.6 RLN92218.1 - 0.18 11.8 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain EF-hand_8 PF13833.6 RLN92219.1 - 1.6e-34 117.5 7.9 2.8e-09 36.7 0.0 5.7 5 0 0 5 5 5 5 EF-hand domain pair EF-hand_1 PF00036.32 RLN92219.1 - 6.6e-16 56.6 19.7 4.1e-05 22.8 0.2 6.2 7 0 0 7 7 7 4 EF hand EF-hand_7 PF13499.6 RLN92219.1 - 5.3e-14 52.4 16.3 0.0004 20.8 0.3 6.3 5 2 1 6 6 6 4 EF-hand domain pair EF-hand_6 PF13405.6 RLN92219.1 - 3.1e-11 42.3 34.1 0.0031 17.3 0.1 8.6 11 0 0 11 11 11 4 EF-hand domain EF-hand_5 PF13202.6 RLN92219.1 - 1.1e-07 31.0 19.8 0.001 18.4 1.0 4.8 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.7 RLN92219.1 - 0.0011 18.8 1.5 3.1 7.8 0.2 3.6 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand SpoIISB_antitox PF14185.6 RLN92219.1 - 0.43 10.5 3.7 6.9 6.6 0.1 3.6 4 0 0 4 4 4 0 Antitoxin SpoIISB, type II toxin-antitoxin system L27_N PF09060.10 RLN92219.1 - 0.66 10.1 3.7 89 3.3 0.1 3.5 3 0 0 3 3 3 0 L27_N PH_12 PF16457.5 RLN92220.1 - 0.061 13.9 0.3 0.2 12.2 0.2 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain rRNA_proc-arch PF13234.6 RLN92221.1 - 0.031 14.2 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 rRNA-processing arch domain AF-4 PF05110.13 RLN92221.1 - 1 7.4 10.1 1.3 7.0 10.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TPR_1 PF00515.28 RLN92222.1 - 5.7e-114 367.8 29.2 5.8e-10 38.6 0.0 13.3 13 0 0 13 13 13 13 Tetratricopeptide repeat TPR_2 PF07719.17 RLN92222.1 - 7.9e-92 294.2 38.5 2.4e-08 33.5 0.1 13.4 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_11 PF13414.6 RLN92222.1 - 3.6e-78 257.0 36.1 9.5e-09 34.8 0.5 13.6 3 2 11 14 14 14 12 TPR repeat TPR_8 PF13181.6 RLN92222.1 - 1.1e-65 212.4 14.8 2.9e-05 23.9 0.0 13.4 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_17 PF13431.6 RLN92222.1 - 3.1e-65 212.0 27.9 5e-06 26.5 0.0 14.1 14 0 0 14 14 14 11 Tetratricopeptide repeat TPR_16 PF13432.6 RLN92222.1 - 3e-52 175.0 46.2 5.4e-10 39.8 0.6 8.6 5 2 5 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.6 RLN92222.1 - 7.3e-43 144.7 39.9 3.7e-09 36.8 0.4 9.7 3 3 7 10 10 10 10 Tetratricopeptide repeat TPR_9 PF13371.6 RLN92222.1 - 1.7e-39 133.8 34.8 2.7e-09 37.0 0.6 9.8 3 3 9 12 12 12 11 Tetratricopeptide repeat TPR_7 PF13176.6 RLN92222.1 - 7.6e-30 100.7 38.8 0.0064 16.4 0.1 13.8 14 0 0 14 14 14 8 Tetratricopeptide repeat TPR_14 PF13428.6 RLN92222.1 - 4.5e-27 92.4 36.8 0.03 15.1 0.2 13.1 2 2 11 13 13 13 8 Tetratricopeptide repeat TPR_19 PF14559.6 RLN92222.1 - 1.5e-25 89.5 32.5 0.00015 22.2 0.2 9.6 5 3 5 10 10 10 8 Tetratricopeptide repeat TPR_6 PF13174.6 RLN92222.1 - 6e-25 86.2 37.6 0.13 13.0 0.2 13.3 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_10 PF13374.6 RLN92222.1 - 4.9e-20 70.7 44.5 0.0028 17.4 0.5 11.7 12 0 0 12 12 12 7 Tetratricopeptide repeat SHNi-TPR PF10516.9 RLN92222.1 - 2e-17 62.3 19.5 0.12 11.8 0.0 11.6 12 0 0 12 12 12 5 SHNi-TPR ANAPC3 PF12895.7 RLN92222.1 - 3.8e-17 62.3 22.4 0.0047 17.1 0.6 7.5 2 2 6 8 8 8 7 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 RLN92222.1 - 1.3e-07 31.6 19.7 0.24 11.5 0.0 9.2 9 0 0 9 9 9 2 MIT (microtubule interacting and transport) domain NARP1 PF12569.8 RLN92222.1 - 1.3e-07 31.0 9.3 0.028 13.3 0.1 5.4 2 1 4 6 6 6 3 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.6 RLN92222.1 - 1.4e-07 31.4 23.6 0.014 15.4 0.2 9.2 9 1 1 10 10 10 2 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 RLN92222.1 - 2e-06 28.0 11.6 8.5 6.4 0.0 8.9 3 3 5 9 9 9 0 Domain of Unknown Function (DUF3856) BTAD PF03704.17 RLN92222.1 - 2.3e-06 28.1 21.9 0.092 13.2 2.1 5.6 2 1 3 5 5 5 3 Bacterial transcriptional activator domain TPR_4 PF07721.14 RLN92222.1 - 7e-06 26.2 7.5 25 5.9 0.0 8.7 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_5 PF12688.7 RLN92222.1 - 0.0024 18.1 18.6 1.6 9.0 0.2 6.0 4 1 2 6 6 5 1 Tetratrico peptide repeat TPR_20 PF14561.6 RLN92222.1 - 0.061 13.7 22.6 1.6 9.1 0.6 6.3 5 1 1 6 6 6 0 Tetratricopeptide repeat DUF627 PF04781.12 RLN92222.1 - 0.072 13.1 1.2 16 5.5 0.1 3.9 2 1 0 3 3 3 0 Protein of unknown function (DUF627) Scramblase PF03803.15 RLN92223.1 - 8e-13 48.2 0.1 8e-05 22.0 0.0 3.2 3 1 0 3 3 3 3 Scramblase Coprogen_oxidas PF01218.18 RLN92224.1 - 0.09 11.5 0.2 0.16 10.7 0.2 1.3 1 0 0 1 1 1 0 Coproporphyrinogen III oxidase Peroxidase_2 PF01328.17 RLN92226.1 - 9.6e-46 156.7 0.0 1.2e-45 156.3 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Peroxidase_2 PF01328.17 RLN92227.1 - 3e-47 161.6 0.0 3.9e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Sec1 PF00995.23 RLN92228.1 - 2.2e-58 198.9 0.0 2.8e-58 198.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Sugar_tr PF00083.24 RLN92229.1 - 3.3e-100 336.1 23.4 3.7e-100 335.9 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN92229.1 - 5.5e-29 101.2 33.1 6.1e-21 74.7 8.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 RLN92229.1 - 0.0045 15.3 0.2 0.0045 15.3 0.2 1.7 2 0 0 2 2 2 1 BT1 family DUF3054 PF11255.8 RLN92229.1 - 0.021 15.3 0.2 0.021 15.3 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3054) Peroxidase_2 PF01328.17 RLN92230.1 - 2.7e-49 168.3 0.0 3.2e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 NUP50 PF08911.11 RLN92230.1 - 0.013 16.2 0.1 0.02 15.5 0.1 1.4 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) p450 PF00067.22 RLN92231.1 - 1.6e-69 234.9 0.0 1.8e-69 234.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SLC12 PF03522.15 RLN92232.1 - 0.15 11.1 2.3 0.2 10.6 2.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF5437 PF17505.2 RLN92232.1 - 0.23 11.5 2.2 0.46 10.5 0.2 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5437) Hid1 PF12722.7 RLN92232.1 - 2.9 5.9 6.9 3.9 5.5 6.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MIT PF04212.18 RLN92234.1 - 0.0066 16.5 0.2 0.0066 16.5 0.2 2.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain DUF3446 PF11928.8 RLN92234.1 - 0.036 14.4 2.7 6.4 7.1 0.5 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Turandot PF07240.11 RLN92234.1 - 0.15 12.1 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot CLPTM1 PF05602.12 RLN92236.1 - 4.2e-65 220.4 5.6 5.3e-65 220.1 5.6 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 RLN92236.1 - 0.02 14.7 5.6 0.033 13.9 1.3 2.6 2 1 0 2 2 2 0 PQ loop repeat TMEM208_SND2 PF05620.11 RLN92236.1 - 0.023 14.5 4.7 0.034 13.9 4.0 1.7 1 1 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 LRR_6 PF13516.6 RLN92237.1 - 2.8e-14 51.9 12.3 0.048 13.7 0.0 5.7 5 0 0 5 5 5 5 Leucine Rich repeat LRR_4 PF12799.7 RLN92237.1 - 0.00035 20.9 13.2 0.41 11.1 0.9 3.7 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN92237.1 - 0.00096 19.4 9.0 1.8 9.4 0.0 4.9 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.6 RLN92237.1 - 0.002 17.9 12.4 0.025 14.3 6.9 4.0 2 2 2 4 4 4 3 Leucine rich repeat Epimerase_2 PF02350.19 RLN92237.1 - 0.012 14.5 0.1 0.019 13.8 0.1 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase IQ PF00612.27 RLN92238.1 - 0.00019 20.9 0.3 0.00055 19.5 0.3 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif ISG65-75 PF11727.8 RLN92238.1 - 2 7.6 16.9 0.018 14.3 7.5 2.1 2 1 1 3 3 3 0 Invariant surface glycoprotein Vps26 PF03643.15 RLN92240.1 - 3.4e-18 65.6 0.0 2.9e-15 56.0 0.0 2.2 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 26 ADH_N PF08240.12 RLN92242.1 - 2.9e-25 88.3 2.9 5.6e-25 87.3 2.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN92242.1 - 4.2e-17 62.3 0.3 7.2e-17 61.6 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN92242.1 - 2.7e-07 31.7 0.0 4.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN92242.1 - 0.00043 19.7 0.1 0.00087 18.7 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN92242.1 - 0.005 16.2 0.5 0.0085 15.4 0.5 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N PF08240.12 RLN92243.1 - 8e-27 93.3 2.6 1.6e-26 92.3 2.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN92243.1 - 9.6e-18 64.4 0.8 1.7e-17 63.7 0.8 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN92243.1 - 1.4e-06 29.4 0.1 2.2e-06 28.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN92243.1 - 0.00016 21.1 0.4 0.00072 19.0 0.2 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN92243.1 - 0.033 13.5 0.7 0.054 12.8 0.7 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain KR PF08659.10 RLN92243.1 - 0.06 13.3 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 KR domain GFO_IDH_MocA PF01408.22 RLN92243.1 - 0.061 14.2 0.1 0.17 12.7 0.1 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Oxidored_nitro PF00148.19 RLN92243.1 - 0.063 12.0 0.0 0.096 11.4 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Ank_2 PF12796.7 RLN92244.1 - 2.2e-47 159.6 6.5 2.3e-15 56.9 0.1 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN92244.1 - 5.7e-37 125.6 1.0 4.5e-08 33.5 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 RLN92244.1 - 3.2e-22 77.9 2.3 0.0019 18.6 0.0 5.9 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 RLN92244.1 - 4.9e-22 75.6 0.4 0.043 14.4 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 RLN92244.1 - 9.9e-22 76.7 3.7 3.4e-07 30.4 0.1 5.5 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 RLN92244.1 - 5.2e-09 35.8 0.0 9.5e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN92244.1 - 5.4e-07 29.2 0.0 8.6e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain BMC PF00936.19 RLN92244.1 - 0.18 11.8 7.0 6.8 6.8 0.2 3.4 1 1 2 3 3 3 0 BMC domain UQ_con PF00179.26 RLN92245.1 - 2.6e-26 91.9 0.1 8.6e-26 90.3 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme EAF PF09816.9 RLN92245.1 - 2.2e-12 47.2 0.0 5.5e-12 46.0 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor Pex26 PF07163.12 RLN92247.1 - 0.16 11.3 1.8 0.19 11.0 1.8 1.1 1 0 0 1 1 1 0 Pex26 protein DUF4570 PF15134.6 RLN92247.1 - 0.27 11.3 7.1 0.35 10.9 6.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4570) FAM60A PF15396.6 RLN92247.1 - 3.6 7.5 7.3 4.2 7.3 7.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Kinesin PF00225.23 RLN92248.1 - 4.4e-100 334.9 0.8 1.1e-99 333.5 0.8 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN92248.1 - 7.9e-17 61.6 0.0 3e-16 59.7 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding VPS38 PF17649.1 RLN92248.1 - 0.053 12.4 15.3 0.046 12.6 1.2 2.5 2 1 0 2 2 2 0 Vacuolar protein sorting 38 Jnk-SapK_ap_N PF09744.9 RLN92248.1 - 0.12 12.6 43.9 0.88 9.8 15.2 3.8 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 GAS PF13851.6 RLN92248.1 - 0.13 11.6 40.5 0.13 11.6 15.8 3.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding MSA-2c PF12238.8 RLN92248.1 - 0.73 9.8 5.6 0.35 10.8 2.4 2.1 1 1 1 2 2 2 0 Merozoite surface antigen 2c DUF3037 PF11236.8 RLN92248.1 - 2.8 8.4 7.3 1.5 9.3 0.4 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3037) MbeD_MobD PF04899.12 RLN92248.1 - 4.4 7.5 12.3 0.17 12.0 0.5 3.3 2 1 0 2 2 2 0 MbeD/MobD like DUF948 PF06103.11 RLN92248.1 - 5.3 7.4 11.0 13 6.2 0.1 4.4 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) HMMR_N PF15905.5 RLN92248.1 - 8.8 5.7 43.0 2.4 7.6 16.5 4.3 4 0 0 4 4 4 0 Hyaluronan mediated motility receptor N-terminal Methyltransf_16 PF10294.9 RLN92249.1 - 4.4e-14 52.6 0.0 6.2e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_11 PF08241.12 RLN92249.1 - 0.026 15.2 0.0 0.06 14.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Secretin_N_2 PF07655.13 RLN92249.1 - 0.03 14.9 0.0 1.2 9.7 0.0 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain VWA_2 PF13519.6 RLN92250.1 - 6.8e-15 55.6 0.1 2.2e-14 54.0 0.0 1.9 2 1 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 RLN92250.1 - 7.7e-05 22.6 0.2 9.7e-05 22.3 0.2 1.1 1 0 0 1 1 1 1 Ssl1-like zf-CSL PF05207.13 RLN92251.1 - 1.5e-23 82.3 1.2 2.5e-23 81.5 1.2 1.4 1 0 0 1 1 1 1 CSL zinc finger Roc PF08477.13 RLN92252.1 - 1.3e-05 25.4 0.0 0.0021 18.2 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RLN92252.1 - 4.1e-05 23.2 0.0 0.0011 18.6 0.0 2.4 2 1 0 2 2 2 1 Ras family NADH-u_ox-rdase PF10785.9 RLN92253.1 - 1.5e-24 86.5 0.1 1.8e-24 86.2 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF4131 PF13567.6 RLN92253.1 - 0.13 11.9 0.2 0.33 10.6 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) GlcNAc PF11397.8 RLN92255.1 - 6.5e-44 150.8 0.0 1.7e-37 129.7 0.0 2.7 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) AAA PF00004.29 RLN92258.1 - 7.4e-14 52.3 0.0 1.1e-12 48.5 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN92258.1 - 5.5e-07 30.1 7.6 4e-06 27.3 0.1 3.3 2 1 2 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 RLN92258.1 - 1.4e-06 28.6 1.1 2.5e-05 24.6 0.8 2.6 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 RLN92258.1 - 4.2e-06 26.8 0.1 2e-05 24.6 0.1 2.2 1 1 0 1 1 1 1 NACHT domain ABC_tran PF00005.27 RLN92258.1 - 0.00036 21.0 0.0 0.0022 18.5 0.0 2.1 2 0 0 2 2 2 1 ABC transporter FtsK_SpoIIIE PF01580.18 RLN92258.1 - 0.001 18.5 0.3 0.0056 16.1 0.1 2.2 1 1 1 2 2 2 1 FtsK/SpoIIIE family ATPase_2 PF01637.18 RLN92258.1 - 0.0013 18.7 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 RLN92258.1 - 0.0027 17.3 1.0 0.66 9.5 0.3 2.6 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 RLN92258.1 - 0.0033 17.2 0.1 0.028 14.2 0.0 2.4 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 RLN92258.1 - 0.004 16.9 0.0 0.043 13.6 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 RLN92258.1 - 0.0068 16.6 0.1 0.017 15.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 RLN92258.1 - 0.0076 16.0 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.6 RLN92258.1 - 0.013 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 RLN92258.1 - 0.016 14.4 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 RLN92258.1 - 0.027 15.0 0.0 0.061 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RLN92258.1 - 0.032 14.0 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 RLN92258.1 - 0.035 14.2 0.2 0.2 11.8 0.1 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 RLN92258.1 - 0.038 14.4 0.0 0.076 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.14 RLN92258.1 - 0.045 13.0 0.1 6.4 5.9 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain T2SSE PF00437.20 RLN92258.1 - 0.061 12.4 0.0 0.14 11.2 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 RLN92258.1 - 0.066 13.2 0.0 0.23 11.5 0.0 1.9 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) Adeno_IVa2 PF02456.15 RLN92258.1 - 0.071 11.9 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein cobW PF02492.19 RLN92258.1 - 0.075 12.6 0.4 1.6 8.3 0.1 2.4 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ribosomal_S5 PF00333.20 RLN92258.1 - 0.57 10.2 2.7 0.45 10.5 0.5 2.0 2 0 0 2 2 2 0 Ribosomal protein S5, N-terminal domain Voltage_CLC PF00654.20 RLN92259.1 - 5.5e-62 210.1 24.6 3.2e-60 204.2 17.3 2.3 2 1 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 RLN92259.1 - 0.023 15.1 0.1 0.25 11.8 0.0 2.6 2 0 0 2 2 2 0 CBS domain Spidroin_N PF16763.5 RLN92261.1 - 0.028 14.4 0.7 0.028 14.4 0.7 2.5 2 1 1 3 3 3 0 Major ampullate spidroin 1, spider silk protein 1, N-term MazG-like PF12643.7 RLN92261.1 - 0.073 13.3 2.5 0.12 12.7 0.5 2.2 2 0 0 2 2 2 0 MazG-like family DUF2576 PF10845.8 RLN92261.1 - 0.089 12.4 2.1 4.3 7.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2576) Roughex PF06020.11 RLN92262.1 - 0.29 10.2 6.9 0.11 11.6 4.5 1.4 2 0 0 2 2 2 0 Drosophila roughex protein RAP1 PF07218.11 RLN92262.1 - 0.62 8.3 7.6 1 7.6 7.6 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 RLN92262.1 - 4.9 5.6 11.9 5.6 5.4 11.9 1.1 1 0 0 1 1 1 0 Macoilin family RabGAP-TBC PF00566.18 RLN92264.1 - 1.3e-12 47.9 0.0 6.9e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain WW PF00397.26 RLN92264.1 - 2.4e-06 27.5 1.0 5e-06 26.5 1.0 1.5 1 0 0 1 1 1 1 WW domain Rhodanese PF00581.20 RLN92264.1 - 0.0033 17.9 0.0 0.027 15.0 0.0 2.4 1 1 0 1 1 1 1 Rhodanese-like domain CDC24_OB2 PF17245.2 RLN92265.1 - 9.3e-19 68.3 0.0 1.9e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 2 CDC24_OB1 PF17246.2 RLN92265.1 - 6.7e-16 58.5 0.0 1.6e-15 57.2 0.0 1.6 2 0 0 2 2 2 1 Cell division control protein 24, OB domain 1 CDC24_OB3 PF17244.2 RLN92265.1 - 8.4e-11 42.0 0.1 7.2e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 Cell division control protein 24, OB domain 3 TraO PF10626.9 RLN92265.1 - 0.19 11.5 0.0 0.42 10.4 0.0 1.5 1 0 0 1 1 1 0 Conjugative transposon protein TraO Peroxidase_2 PF01328.17 RLN92266.1 - 7.8e-48 163.5 0.0 9.5e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Peroxidase_2 PF01328.17 RLN92267.1 - 3e-49 168.1 0.0 4.1e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Peroxidase_2 PF01328.17 RLN92268.1 - 1.2e-47 162.9 0.0 1.5e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Peroxidase_2 PF01328.17 RLN92269.1 - 9.2e-48 163.3 0.0 1.2e-47 162.9 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 BTB PF00651.31 RLN92270.1 - 0.12 12.6 0.0 6.3 7.1 0.0 2.6 3 0 0 3 3 3 0 BTB/POZ domain Thioredoxin_8 PF13905.6 RLN92274.1 - 1.3e-19 70.3 0.0 2.3e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 RLN92274.1 - 9e-06 25.6 0.0 0.024 14.6 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 RLN92274.1 - 7.8e-05 23.1 0.0 0.00015 22.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 RLN92274.1 - 0.00028 20.7 0.0 0.085 12.6 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.6 RLN92274.1 - 0.057 13.6 0.1 0.17 12.1 0.1 1.9 1 1 0 1 1 1 0 Thioredoxin-like CoA_transf_3 PF02515.17 RLN92275.1 - 1.1e-111 373.5 0.0 1.3e-111 373.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III PLDc PF00614.22 RLN92276.1 - 7.8e-08 32.2 0.1 2.1e-07 30.8 0.1 1.8 1 0 0 1 1 1 1 Phospholipase D Active site motif PLDc_2 PF13091.6 RLN92276.1 - 0.0043 17.0 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 PLD-like domain PX PF00787.24 RLN92276.1 - 0.021 14.8 0.2 0.043 13.8 0.2 1.5 1 0 0 1 1 1 0 PX domain Pkinase_Tyr PF07714.17 RLN92277.1 - 4.1e-47 160.6 0.0 1.8e-39 135.6 0.0 4.0 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN92277.1 - 7.2e-43 146.9 0.0 6.4e-39 133.9 0.0 3.6 3 1 0 3 3 3 2 Protein kinase domain Pkinase_fungal PF17667.1 RLN92277.1 - 0.0021 16.9 0.0 0.0035 16.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN92277.1 - 0.019 14.9 0.9 0.068 13.1 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Beta-prism_lec PF16458.5 RLN92277.1 - 0.14 12.2 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Beta-prism lectin SNF2_N PF00176.23 RLN92278.1 - 2.4e-65 220.6 0.1 5e-65 219.5 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN92278.1 - 8.8e-19 67.9 0.0 1.9e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN92278.1 - 4.6e-10 39.8 0.0 1.2e-09 38.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 RLN92278.1 - 5e-10 39.6 8.0 5e-10 39.6 8.0 4.6 3 1 2 5 5 5 1 HSA WW PF00397.26 RLN92278.1 - 3.8e-05 23.7 0.0 9.4e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 WW domain F-box-like PF12937.7 RLN92278.1 - 0.00021 21.1 0.1 0.00061 19.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like DEAD PF00270.29 RLN92278.1 - 0.00093 19.0 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 RLN92278.1 - 0.001 18.3 0.0 0.0025 17.1 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase E1-E2_ATPase PF00122.20 RLN92280.1 - 5.2e-43 146.7 3.6 6.6e-29 100.7 0.4 3.1 1 1 1 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 RLN92280.1 - 2.8e-39 134.7 0.2 2.8e-39 134.7 0.2 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 RLN92280.1 - 3.6e-19 68.7 0.0 1.3e-18 66.8 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RLN92280.1 - 4.8e-18 66.2 0.5 1.7e-16 61.2 0.5 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase C2 PF00168.30 RLN92280.1 - 6e-17 61.8 0.0 1.7e-16 60.3 0.0 1.8 1 0 0 1 1 1 1 C2 domain Cation_ATPase_N PF00690.26 RLN92280.1 - 7.1e-16 57.7 0.0 1.6e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RLN92280.1 - 0.0032 17.2 0.7 0.0054 16.5 0.7 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase_Tyr PF07714.17 RLN92282.1 - 1.2e-51 175.5 0.0 5.8e-41 140.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN92282.1 - 2.2e-44 151.8 0.0 1.4e-34 119.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Arm PF00514.23 RLN92282.1 - 1.2e-25 88.7 41.0 0.11 12.6 0.0 20.6 21 1 0 22 22 22 8 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN92282.1 - 5.8e-10 38.6 26.9 68 4.1 0.1 16.3 17 0 0 17 17 17 0 HEAT repeat Uso1_p115_head PF04869.14 RLN92282.1 - 2.3e-06 27.0 1.0 20 4.2 0.0 6.0 6 0 0 6 6 6 0 Uso1 / p115 like vesicle tethering protein, head region HEAT_2 PF13646.6 RLN92282.1 - 4.3e-05 23.8 52.5 0.0014 19.0 1.0 9.6 5 2 6 12 12 12 4 HEAT repeats HEAT_EZ PF13513.6 RLN92282.1 - 0.0035 17.8 54.3 0.41 11.2 0.1 12.1 12 1 2 14 14 14 4 HEAT-like repeat MRF_C1 PF13887.6 RLN92282.1 - 0.015 14.5 0.1 7.1 5.9 0.0 2.7 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 Kinase-like PF14531.6 RLN92282.1 - 0.015 14.6 0.0 3.8 6.7 0.0 3.1 3 0 0 3 3 3 0 Kinase-like CBM_11 PF03425.13 RLN92282.1 - 0.089 12.7 0.0 6.8 6.5 0.0 2.6 2 0 0 2 2 2 0 Carbohydrate binding domain (family 11) HTH_7 PF02796.15 RLN92282.1 - 0.33 11.1 4.1 59 3.9 0.1 5.0 4 0 0 4 4 4 0 Helix-turn-helix domain of resolvase Glyco_hydro_3_C PF01915.22 RLN92284.1 - 1.3e-48 165.7 0.0 2e-48 165.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 RLN92284.1 - 3.4e-35 122.0 0.0 1.4e-34 119.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 RLN92284.1 - 6.1e-06 26.3 0.2 1.6e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain DAO PF01266.24 RLN92285.1 - 4.3e-52 177.8 0.0 6.1e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 RLN92285.1 - 4.3e-35 120.3 0.0 7.6e-35 119.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 RLN92285.1 - 8.6e-10 38.3 3.5 2.7e-05 23.4 1.2 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 RLN92285.1 - 0.00029 20.1 0.1 0.0034 16.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 RLN92285.1 - 0.00089 18.4 1.7 0.11 11.5 0.9 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 RLN92285.1 - 0.003 17.0 2.7 0.003 17.0 2.7 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 RLN92285.1 - 0.012 14.3 0.6 0.025 13.3 0.6 1.5 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 RLN92285.1 - 0.022 14.0 2.1 0.34 10.1 0.3 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RLN92285.1 - 0.024 13.9 0.1 1.3 8.2 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 RLN92285.1 - 0.077 13.2 0.4 0.077 13.2 0.4 2.6 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 RLN92285.1 - 0.1 12.9 0.0 1.8 8.8 0.0 2.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 RLN92285.1 - 0.12 12.9 1.6 0.68 10.5 0.3 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 RLN92285.1 - 2.6 7.2 4.9 1.2 8.4 0.1 2.7 3 0 0 3 3 3 0 Thi4 family Acyltransferase PF01553.21 RLN92286.1 - 0.00029 20.5 0.0 0.11 12.2 0.0 2.3 1 1 1 2 2 2 2 Acyltransferase Arm PF00514.23 RLN92287.1 - 7.8e-07 28.9 31.0 0.06 13.4 0.1 10.4 11 0 0 11 11 11 4 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 RLN92287.1 - 8e-05 22.6 20.3 0.0092 16.0 0.0 8.6 9 0 0 9 9 9 2 Spinocerebellar ataxia type 10 protein domain WW PF00397.26 RLN92287.1 - 0.065 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 WW domain NTP_transferase PF00483.23 RLN92287.1 - 0.15 11.6 4.6 0.072 12.7 0.2 2.8 3 0 0 3 3 3 0 Nucleotidyl transferase HEAT_PBS PF03130.16 RLN92287.1 - 1.2 10.1 17.1 11 7.0 0.1 6.7 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat zf-RING_2 PF13639.6 RLN92289.1 - 0.2 12.0 0.2 0.2 12.0 0.2 2.7 3 0 0 3 3 3 0 Ring finger domain Arm PF00514.23 RLN92291.1 - 1e-05 25.4 8.1 0.014 15.5 0.0 5.2 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Cutinase PF01083.22 RLN92291.1 - 0.00018 21.5 0.0 0.00055 19.9 0.0 1.7 2 0 0 2 2 2 1 Cutinase Abhydrolase_6 PF12697.7 RLN92291.1 - 0.00025 21.7 2.2 0.0011 19.7 0.1 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family HEAT_2 PF13646.6 RLN92291.1 - 0.017 15.5 15.3 2 8.9 0.0 5.6 5 2 0 5 5 5 0 HEAT repeats HEAT PF02985.22 RLN92291.1 - 0.023 14.9 2.7 0.22 11.9 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat DUF3585 PF12130.8 RLN92291.1 - 0.031 14.4 0.2 0.088 12.9 0.2 1.8 1 0 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain LCAT PF02450.15 RLN92291.1 - 0.033 13.4 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Cnd1 PF12717.7 RLN92291.1 - 0.036 14.1 0.4 0.24 11.5 0.0 2.5 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF676 PF05057.14 RLN92291.1 - 0.04 13.4 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 RLN92291.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Mo25 PF08569.11 RLN92291.1 - 0.08 12.3 0.1 0.82 9.0 0.1 2.1 2 0 0 2 2 2 0 Mo25-like Ank_2 PF12796.7 RLN92292.1 - 2.4e-40 137.0 2.4 1.3e-12 48.1 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 RLN92292.1 - 6.6e-38 130.5 0.0 2e-37 128.9 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RLN92292.1 - 2.6e-36 125.3 0.0 4.1e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 RLN92292.1 - 2e-22 79.3 7.0 9.7e-09 35.6 0.1 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN92292.1 - 4.4e-21 74.7 4.0 9.8e-08 32.1 0.1 4.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Arm PF00514.23 RLN92292.1 - 2e-18 65.7 8.1 0.00088 19.2 0.1 7.7 7 0 0 7 7 7 5 Armadillo/beta-catenin-like repeat Ank PF00023.30 RLN92292.1 - 3.7e-17 61.9 8.4 0.00086 19.7 0.1 6.4 7 0 0 7 7 6 4 Ankyrin repeat Ank_3 PF13606.6 RLN92292.1 - 3.1e-16 57.8 0.3 0.0064 16.9 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat Atx10homo_assoc PF09759.9 RLN92292.1 - 7.9e-09 35.4 2.1 0.035 14.1 0.1 3.8 2 1 1 3 3 3 3 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 RLN92292.1 - 0.0058 17.1 5.8 1.9 9.0 0.1 4.0 3 0 0 3 3 3 2 HEAT-like repeat VHS PF00790.19 RLN92292.1 - 0.014 15.3 0.0 4.9 7.0 0.0 2.4 2 0 0 2 2 2 0 VHS domain SRA1 PF07304.11 RLN92292.1 - 0.035 13.9 0.1 0.08 12.7 0.1 1.5 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) Kinase-like PF14531.6 RLN92292.1 - 0.089 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 RLN92293.1 - 7.7e-31 107.4 0.0 1.3e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92293.1 - 1.7e-20 73.4 0.0 6.3e-20 71.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 RLN92293.1 - 1e-05 25.3 10.2 0.15 12.4 0.0 5.6 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 RLN92293.1 - 0.00083 19.8 0.6 2.5 8.7 0.3 4.2 2 1 1 3 3 3 2 HEAT-like repeat Seadorna_VP7 PF07387.11 RLN92293.1 - 0.0079 15.3 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Vac14_Fab1_bd PF12755.7 RLN92293.1 - 0.14 12.8 0.0 2.8 8.6 0.0 3.0 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region TAF6_C PF07571.13 RLN92293.1 - 0.14 12.5 0.0 0.6 10.5 0.0 2.1 1 1 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain CLASP_N PF12348.8 RLN92293.1 - 0.17 11.4 0.0 7.5 6.0 0.0 2.9 3 0 0 3 3 3 0 CLASP N terminal ACOX PF01756.19 RLN92294.1 - 5.3e-52 176.0 0.0 8e-52 175.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 RLN92294.1 - 9e-33 113.5 0.0 1.5e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 RLN92294.1 - 9.2e-12 45.0 0.0 2.5e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 RLN92294.1 - 0.0067 17.1 0.0 0.023 15.4 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 RLN92294.1 - 0.059 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Arm PF00514.23 RLN92297.1 - 5.5e-24 83.4 5.1 4e-05 23.5 0.0 5.6 5 1 0 5 5 5 5 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN92297.1 - 5.2e-09 35.6 1.4 2.9 8.4 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat DUF397 PF04149.12 RLN92297.1 - 7.5e-06 25.9 1.7 2.5 8.3 0.0 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF397) HEAT_EZ PF13513.6 RLN92297.1 - 2.3e-05 24.8 4.9 0.24 11.9 0.4 3.4 3 1 0 3 3 3 2 HEAT-like repeat Atx10homo_assoc PF09759.9 RLN92297.1 - 0.0001 22.3 1.8 0.04 13.9 0.1 3.0 1 1 3 4 4 4 3 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 RLN92297.1 - 0.00014 22.2 11.0 0.0021 18.4 3.2 3.0 1 1 2 3 3 3 3 HEAT repeats UNC45-central PF11701.8 RLN92297.1 - 0.00041 20.3 0.0 0.15 12.0 0.0 2.7 1 1 2 3 3 3 1 Myosin-binding striated muscle assembly central FERM_F1 PF18379.1 RLN92297.1 - 0.00051 20.0 0.0 15 5.7 0.0 4.0 1 1 3 4 4 4 0 FERM F1 ubiquitin-like domain Tex_N PF09371.10 RLN92297.1 - 0.00075 19.2 2.3 18 4.9 0.1 4.6 1 1 4 5 5 5 0 Tex-like protein N-terminal domain HEAT_PBS PF03130.16 RLN92297.1 - 0.00078 19.9 6.3 24 6.0 0.0 5.2 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat TM1506 PF08973.10 RLN92297.1 - 0.0013 18.4 0.0 28 4.4 0.0 4.2 2 2 3 5 5 5 0 Domain of unknown function (DUF1893) Arm_2 PF04826.13 RLN92297.1 - 0.0016 18.0 0.0 0.54 9.7 0.0 2.2 1 1 1 2 2 2 2 Armadillo-like DUF4402 PF14352.6 RLN92297.1 - 0.0048 17.5 0.0 3 8.5 0.0 3.2 1 1 2 3 3 3 1 Domain of unknown function (DUF4402) DDE_1 PF03184.19 RLN92298.1 - 5.5e-11 42.4 0.0 1.5e-10 41.0 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Arm PF00514.23 RLN92299.1 - 6.7e-23 79.9 16.8 0.0011 18.9 0.1 7.2 7 0 0 7 7 7 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN92299.1 - 1.1e-06 29.0 12.9 0.25 11.9 0.7 5.5 4 2 2 6 6 6 4 HEAT-like repeat DUF1654 PF07867.11 RLN92299.1 - 3.3e-05 23.5 3.0 1 9.2 0.1 5.4 2 1 5 7 7 7 2 Protein of unknown function (DUF1654) HEAT PF02985.22 RLN92299.1 - 0.0015 18.6 9.7 53 4.5 0.0 7.7 7 1 1 8 8 8 0 HEAT repeat FERM_F1 PF18379.1 RLN92299.1 - 0.0079 16.2 0.0 1.4 9.0 0.0 3.9 2 1 2 4 4 4 1 FERM F1 ubiquitin-like domain UNC45-central PF11701.8 RLN92299.1 - 0.017 15.1 0.0 4.6 7.2 0.0 3.1 1 1 1 3 3 3 0 Myosin-binding striated muscle assembly central DUF397 PF04149.12 RLN92299.1 - 0.081 13.0 8.4 7.1 6.8 0.1 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF397) HEAT_PBS PF03130.16 RLN92299.1 - 2.7 8.9 20.7 62 4.7 0.0 7.0 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat Dimer_Tnp_hAT PF05699.14 RLN92300.1 - 2.8e-05 23.8 0.1 4.2e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RL11D PF11088.8 RLN92301.1 - 0.069 13.5 0.1 0.076 13.3 0.1 1.3 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 ASH PF15780.5 RLN92303.1 - 1.3e-28 99.1 14.4 5.7e-05 23.3 0.0 12.6 11 2 1 12 12 12 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 RLN92303.1 - 3.3e-17 62.5 4.1 0.00014 22.0 0.0 7.2 8 0 0 8 8 8 3 Flagellar-associated PapD-like TMEM131_like PF12371.8 RLN92303.1 - 2.6e-09 37.2 0.3 6.6 7.1 0.0 9.2 10 1 0 10 10 10 2 Transmembrane protein 131-like Motile_Sperm PF00635.26 RLN92303.1 - 0.0029 17.4 0.0 1.3e+02 2.4 0.0 6.2 8 0 0 8 8 8 0 MSP (Major sperm protein) domain MYCBPAP PF14646.6 RLN92303.1 - 0.0071 15.3 0.1 2.1 7.2 0.0 3.5 4 0 0 4 4 4 1 MYCBP-associated protein family DUF4712 PF15830.5 RLN92305.1 - 0.0016 18.1 0.1 0.0033 17.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4712) FAM76 PF16046.5 RLN92306.1 - 0.15 11.4 0.2 0.23 10.8 0.2 1.2 1 0 0 1 1 1 0 FAM76 protein CCDC-167 PF15188.6 RLN92306.1 - 3.6 8.0 5.9 0.68 10.3 0.6 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 AIP3 PF03915.13 RLN92307.1 - 0.067 12.3 0.2 0.08 12.0 0.2 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 DEAD PF00270.29 RLN92308.1 - 3.8e-06 26.8 0.4 0.014 15.2 0.1 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN92308.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.8 1 1 0 1 1 1 0 Helicase conserved C-terminal domain CBS PF00571.28 RLN92308.1 - 0.057 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 CBS domain Ribosomal_L26 PF16906.5 RLN92309.1 - 2.7e-33 114.3 3.4 5.8e-33 113.2 3.4 1.6 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal Pkinase PF00069.25 RLN92309.1 - 5.4e-26 91.5 0.0 8.6e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92309.1 - 1.1e-17 64.2 0.0 1.6e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KOW PF00467.29 RLN92309.1 - 3.6e-06 26.7 2.2 1.2e-05 25.0 2.2 1.8 1 0 0 1 1 1 1 KOW motif Kdo PF06293.14 RLN92309.1 - 0.00043 19.7 0.0 0.00087 18.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN92309.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like NUDE_C PF04880.13 RLN92309.1 - 0.061 13.8 2.4 0.18 12.3 2.4 1.7 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Dehydrin PF00257.19 RLN92309.1 - 0.099 13.2 1.1 0.19 12.3 1.1 1.4 1 0 0 1 1 1 0 Dehydrin Kinesin PF00225.23 RLN92311.1 - 0.00074 18.5 0.0 0.0023 16.9 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain FtsL PF04999.13 RLN92311.1 - 0.12 12.4 1.9 0.19 11.8 0.3 2.1 2 0 0 2 2 2 0 Cell division protein FtsL Trimer_CC PF08954.11 RLN92311.1 - 0.24 11.0 6.7 1.1 8.9 2.8 3.7 3 0 0 3 3 3 0 Trimerisation motif CpXC PF14353.6 RLN92311.1 - 0.69 10.0 3.6 0.45 10.6 0.9 2.1 2 0 0 2 2 2 0 CpXC protein TLD PF07534.16 RLN92313.1 - 9.2e-19 68.0 0.0 1.9e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 TLD RhoGAP PF00620.27 RLN92313.1 - 5e-14 52.4 0.1 2.4e-13 50.2 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain ELMO_CED12 PF04727.13 RLN92313.1 - 4.4e-11 43.2 0.1 1.4e-10 41.5 0.0 1.9 2 0 0 2 2 2 1 ELMO/CED-12 family RUN PF02759.19 RLN92313.1 - 0.00067 19.6 0.1 0.2 11.6 0.1 2.6 1 1 0 1 1 1 1 RUN domain Adeno_PX PF05829.12 RLN92313.1 - 0.18 11.7 0.9 0.42 10.5 0.9 1.6 1 0 0 1 1 1 0 Adenovirus late L2 mu core protein (Protein X) GLYCAM-1 PF05242.11 RLN92313.1 - 0.18 11.9 0.5 0.5 10.5 0.1 1.9 2 0 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) LUC7 PF03194.15 RLN92313.1 - 0.32 10.6 1.7 0.33 10.6 0.3 1.6 2 0 0 2 2 2 0 LUC7 N_terminus SET PF00856.28 RLN92314.1 - 0.00017 22.1 1.7 0.00036 21.0 0.1 2.1 2 1 0 2 2 2 1 SET domain SR-25 PF10500.9 RLN92314.1 - 0.2 11.3 8.4 0.2 11.3 2.8 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 RLN92314.1 - 1.8 9.3 13.2 2.8 8.7 7.0 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein TUDOR_5 PF18359.1 RLN92315.1 - 1.9e-08 33.9 0.1 5.8e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 Histone methyltransferase Tudor domain 1 Agenet PF05641.12 RLN92315.1 - 2.6e-05 24.6 1.3 0.011 16.2 0.4 2.4 2 0 0 2 2 2 2 Agenet domain Tudor-knot PF11717.8 RLN92315.1 - 0.0076 16.1 0.1 0.038 13.9 0.1 1.9 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain PhoLip_ATPase_C PF16212.5 RLN92316.1 - 4.6e-76 255.9 16.7 7.7e-76 255.1 16.7 1.4 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RLN92316.1 - 3.7e-17 61.8 0.0 9e-17 60.5 0.0 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 RLN92316.1 - 7.2e-11 42.0 0.0 1.7e-09 37.7 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RLN92316.1 - 6.9e-08 33.0 0.1 0.03 14.6 0.0 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RLN92316.1 - 0.0016 18.0 0.0 0.019 14.5 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RLN92316.1 - 0.0049 16.6 0.0 0.0092 15.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CytochromB561_N PF09786.9 RLN92316.1 - 2.1 7.3 5.5 4.1 6.3 5.5 1.4 1 0 0 1 1 1 0 Cytochrome B561, N terminal NUC153 PF08159.12 RLN92318.1 - 5.3e-11 42.1 1.2 1.2e-10 41.0 1.2 1.6 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 RLN92318.1 - 1.5e-05 25.2 0.0 0.25 11.7 0.0 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 RLN92318.1 - 0.032 12.8 0.0 0.063 11.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain SAPS PF04499.15 RLN92318.1 - 0.82 8.4 4.6 1.2 7.9 4.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 RLN92318.1 - 3.8 5.7 14.0 6 5.0 14.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Dzip-like_N PF13815.6 RLN92319.1 - 1.5e-10 41.1 0.0 1.5e-10 41.1 0.0 4.3 3 1 1 4 4 4 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2H2 PF00096.26 RLN92319.1 - 0.0057 17.0 0.2 0.011 16.1 0.2 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type ARS2 PF04959.13 RLN92319.1 - 0.015 15.7 0.2 0.015 15.7 0.2 2.9 2 1 2 4 4 4 0 Arsenite-resistance protein 2 zf-C2H2_4 PF13894.6 RLN92319.1 - 0.026 15.3 0.5 0.062 14.2 0.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf_C2H2_6 PF18450.1 RLN92319.1 - 0.11 12.2 0.1 0.29 10.9 0.1 1.7 1 0 0 1 1 1 0 Zinc Finger domain Ribosomal_S5 PF00333.20 RLN92319.1 - 0.13 12.2 0.4 0.36 10.8 0.4 1.7 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain RecG_N PF17190.4 RLN92319.1 - 1.8 9.4 11.8 0.55 11.0 0.9 2.9 1 1 1 2 2 2 0 RecG N-terminal helical domain Sel1 PF08238.12 RLN92320.1 - 2.5e-06 28.0 0.0 0.2 12.4 0.0 3.8 4 0 0 4 4 4 2 Sel1 repeat PLDc_2 PF13091.6 RLN92321.1 - 1.3e-15 57.5 0.0 2.2e-12 47.0 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 RLN92321.1 - 8.3e-08 32.1 8.3 0.00014 21.9 0.3 3.4 3 1 0 3 3 3 2 Phospholipase D Active site motif Pkinase PF00069.25 RLN92324.1 - 8.9e-62 208.8 0.0 1.2e-61 208.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92324.1 - 2.2e-31 109.1 0.0 3.4e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN92324.1 - 1.8e-07 30.8 0.0 3.7e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like PH PF00169.29 RLN92324.1 - 8.1e-07 29.5 0.1 2e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN92324.1 - 9.2e-06 26.0 1.5 5.8e-05 23.5 1.5 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain APH PF01636.23 RLN92324.1 - 0.001 19.0 0.2 0.0037 17.2 0.2 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN92324.1 - 0.022 13.7 0.0 0.041 12.8 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain PH_8 PF15409.6 RLN92324.1 - 0.023 15.0 0.7 0.13 12.6 0.5 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Pkinase_fungal PF17667.1 RLN92324.1 - 0.038 12.8 0.0 0.079 11.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 RLN92324.1 - 0.073 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PH_13 PF16652.5 RLN92324.1 - 0.095 12.5 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain FTA2 PF13095.6 RLN92324.1 - 0.16 11.5 0.1 21 4.7 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Phage_holin_T PF11031.8 RLN92325.1 - 0.12 11.8 0.1 0.2 11.1 0.1 1.3 1 1 0 1 1 1 0 Bacteriophage T holin FYVE PF01363.21 RLN92326.1 - 1.5e-05 25.0 10.3 2.5e-05 24.3 10.3 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN92326.1 - 0.4 10.9 11.8 1.5 9.1 11.8 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger AAA_9 PF12781.7 RLN92327.1 - 2e-18 66.3 0.0 2.2e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 ATP-binding dynein motor region FTHFS PF01268.19 RLN92328.1 - 1.5e-29 102.6 1.2 8.9e-29 100.1 1.2 1.8 1 1 0 1 1 1 1 Formate--tetrahydrofolate ligase CDC45 PF02724.14 RLN92328.1 - 0.075 11.3 0.5 0.094 11.0 0.5 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM220 PF15487.6 RLN92328.1 - 1.4 8.5 4.0 2.4 7.7 4.0 1.4 1 0 0 1 1 1 0 FAM220 family GBP PF02263.19 RLN92330.1 - 7.3e-30 104.1 2.6 9.5e-17 61.1 0.1 2.3 1 1 0 2 2 2 2 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 RLN92330.1 - 9.1e-06 25.3 0.3 9.1e-06 25.3 0.3 1.9 2 0 0 2 2 2 1 Guanylate-binding protein, C-terminal domain Phage_int_SAM_5 PF13102.6 RLN92330.1 - 0.058 13.7 0.1 0.19 12.1 0.0 1.9 1 1 1 2 2 2 0 Phage integrase SAM-like domain FUSC_2 PF13515.6 RLN92330.1 - 0.1 12.7 0.8 0.22 11.7 0.8 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein-like DUF3322 PF11795.8 RLN92330.1 - 0.15 12.1 1.5 0.27 11.2 0.1 2.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) CAP PF00188.26 RLN92331.1 - 1.1e-08 36.0 0.3 1.3e-08 35.7 0.3 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family BRCT PF00533.26 RLN92332.1 - 1.6e-07 31.6 0.0 0.0029 18.0 0.0 3.2 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 RLN92332.1 - 0.0013 18.5 0.0 0.054 13.4 0.0 2.7 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 RLN92332.1 - 0.0023 18.3 0.4 5.4 7.5 0.1 4.0 4 1 1 5 5 5 2 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 RLN92332.1 - 0.013 15.4 0.1 0.23 11.5 0.0 2.6 2 0 0 2 2 2 0 twin BRCT domain zf-RanBP PF00641.18 RLN92332.1 - 0.47 9.8 5.9 0.81 9.1 5.9 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zinc_ribbon_2 PF13240.6 RLN92332.1 - 7.3 6.5 6.5 13 5.6 6.5 1.4 1 0 0 1 1 1 0 zinc-ribbon domain IPP-2 PF04979.14 RLN92333.1 - 5.2e-20 72.5 7.6 9.3e-20 71.7 7.6 1.4 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) SHIPPO-rpt PF07004.12 RLN92334.1 - 3.3e-19 68.8 19.4 0.0016 19.2 0.4 6.1 6 0 0 6 6 6 5 Sperm-tail PG-rich repeat Pkinase PF00069.25 RLN92335.1 - 1.2e-06 28.1 0.0 6.3e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92335.1 - 4.4e-06 26.2 0.0 1.2e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase ATP-grasp_2 PF08442.10 RLN92336.1 - 1.2e-61 207.8 1.2 1.5e-53 181.3 0.2 3.0 3 0 0 3 3 3 2 ATP-grasp domain Ligase_CoA PF00549.19 RLN92336.1 - 1e-22 80.6 1.3 1e-22 80.6 1.3 1.7 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 RLN92336.1 - 1.3e-06 28.1 0.4 0.03 13.8 0.1 2.5 3 0 0 3 3 3 2 ATP-grasp domain GARS_A PF01071.19 RLN92336.1 - 1.2 8.9 4.4 8.7 6.1 0.3 2.9 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Arf PF00025.21 RLN92337.1 - 2.3e-71 238.9 0.3 2.5e-71 238.7 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 RLN92337.1 - 6.2e-15 55.2 0.7 2.2e-10 40.3 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 RLN92337.1 - 2.1e-13 50.2 0.0 2.4e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 RLN92337.1 - 2.6e-13 49.8 0.0 3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 RLN92337.1 - 6.8e-13 48.9 0.0 9.7e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 RLN92337.1 - 3.8e-10 39.5 0.0 4.4e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RLN92337.1 - 1.6e-06 28.1 0.0 2.5e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RLN92337.1 - 0.00017 21.2 0.0 0.0018 17.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 RLN92337.1 - 0.0099 16.3 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RLN92337.1 - 0.018 15.6 0.0 0.029 14.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 RLN92337.1 - 0.028 14.2 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PAE PF03283.13 RLN92337.1 - 0.1 11.7 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase DUF1974 PF09317.11 RLN92338.1 - 0.076 12.6 3.2 0.11 12.1 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) DUF2408 PF10303.9 RLN92338.1 - 1.9 9.0 8.1 4.3 7.9 7.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) 3HCDH_N PF02737.18 RLN92338.1 - 4.7 7.1 8.4 5.9 6.7 3.6 2.2 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Choline_transpo PF04515.12 RLN92339.1 - 3e-98 329.0 23.3 3e-98 329.0 23.3 2.8 2 1 1 3 3 3 1 Plasma-membrane choline transporter Sec63 PF02889.16 RLN92340.1 - 6.6e-74 248.3 0.0 9.4e-54 182.3 0.0 3.2 2 1 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 RLN92340.1 - 5e-55 186.0 9.5 4.1e-30 104.9 3.5 3.6 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 RLN92340.1 - 6e-23 81.7 0.1 3.2e-14 53.3 0.5 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RLN92340.1 - 4e-13 49.7 0.1 2e-06 28.1 0.0 3.7 3 1 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 RLN92340.1 - 5.2e-10 39.7 3.0 0.00011 22.4 0.4 4.0 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 RLN92340.1 - 3.5e-05 23.0 0.0 0.12 11.4 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_19 PF13245.6 RLN92340.1 - 7.4e-05 23.1 2.9 0.024 15.0 1.0 3.5 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RLN92340.1 - 0.0017 17.9 0.2 0.94 9.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA PF00004.29 RLN92340.1 - 0.0018 18.7 3.2 2 8.8 0.9 4.3 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 RLN92340.1 - 0.0047 16.7 0.3 1.4 8.6 0.0 3.5 3 0 0 3 3 3 1 IstB-like ATP binding protein PhoH PF02562.16 RLN92340.1 - 0.011 15.2 0.0 2 7.8 0.1 2.5 2 0 0 2 2 2 0 PhoH-like protein Amidinotransf PF02274.17 RLN92340.1 - 0.014 14.5 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Amidinotransferase UvrD-helicase PF00580.21 RLN92340.1 - 0.032 13.8 4.1 0.6 9.6 0.2 3.3 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain UTP25 PF06862.12 RLN92340.1 - 0.047 12.5 0.9 1.7 7.3 0.1 2.5 1 1 1 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Helicase_PWI PF18149.1 RLN92340.1 - 0.1 12.8 0.1 0.53 10.5 0.0 2.3 2 0 0 2 2 1 0 N-terminal helicase PWI domain Sigma54_activ_2 PF14532.6 RLN92340.1 - 0.16 12.1 3.3 23 5.1 0.0 3.3 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 RLN92340.1 - 0.22 11.3 18.0 0.22 11.3 0.4 5.4 3 2 2 5 5 5 0 AAA domain Josephin PF02099.17 RLN92341.1 - 4e-09 36.8 0.1 1.1e-08 35.3 0.0 1.7 2 0 0 2 2 2 1 Josephin AhpC-TSA PF00578.21 RLN92342.1 - 1.9e-08 34.3 0.0 9e-08 32.1 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 RLN92342.1 - 1.6e-07 31.5 0.0 5.2e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 RLN92342.1 - 0.0028 17.4 0.0 0.0066 16.2 0.0 1.6 1 1 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 RLN92342.1 - 0.043 13.8 0.0 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_2 PF13098.6 RLN92342.1 - 0.18 12.3 0.0 0.73 10.3 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain CPSase_L_D2 PF02786.17 RLN92343.1 - 1e-75 253.9 0.1 1.6e-75 253.3 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 RLN92343.1 - 1.2e-43 148.2 0.1 2.3e-43 147.2 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 RLN92343.1 - 5.6e-36 122.9 0.0 1.4e-35 121.6 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 RLN92343.1 - 3.9e-17 61.9 1.2 1.4e-16 60.1 1.2 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme PCC_BT PF18140.1 RLN92343.1 - 3.8e-09 37.0 0.1 2.4e-07 31.1 0.0 2.4 2 0 0 2 2 2 1 Propionyl-coenzyme A carboxylase BT domain ATP-grasp PF02222.22 RLN92343.1 - 3.3e-07 30.1 0.0 9.2e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 RLN92343.1 - 4.3e-06 26.4 0.0 1.3e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_ST PF14397.6 RLN92343.1 - 0.0012 18.2 0.0 0.021 14.1 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATP-grasp_5 PF13549.6 RLN92343.1 - 0.0021 17.6 0.0 0.0043 16.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 RLN92343.1 - 0.0058 16.4 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 RLN92343.1 - 0.024 14.7 0.1 0.1 12.6 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain DUF2118 PF09891.9 RLN92343.1 - 0.027 14.4 0.1 0.074 13.0 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) RnfC_N PF13375.6 RLN92343.1 - 0.042 13.8 0.3 0.11 12.4 0.3 1.9 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain cNMP_binding PF00027.29 RLN92344.1 - 9.4e-21 73.7 1.5 7.4e-10 38.8 0.0 3.0 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 RLN92344.1 - 0.17 11.6 0.2 7.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Cupin domain ANAPC4_WD40 PF12894.7 RLN92345.1 - 3.2e-05 24.1 0.1 3.6 8.0 0.0 4.7 3 2 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RLN92345.1 - 0.15 11.4 2.4 2.3 7.5 2.4 2.5 1 1 0 1 1 1 0 WD40-like domain VIT1 PF01988.19 RLN92346.1 - 2.7e-55 187.6 1.2 3.5e-55 187.2 1.2 1.2 1 0 0 1 1 1 1 VIT family DUF4349 PF14257.6 RLN92346.1 - 0.073 12.5 0.1 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) GatB_Yqey PF02637.18 RLN92346.1 - 0.074 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 GatB domain ADH_N PF08240.12 RLN92347.1 - 4.1e-26 91.0 2.8 8e-26 90.1 2.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN92347.1 - 3e-17 62.8 0.7 5e-17 62.1 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN92347.1 - 1.5e-05 26.0 0.0 2.7e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN92347.1 - 0.00026 20.4 0.8 0.0012 18.2 0.2 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN92347.1 - 0.033 13.5 0.5 0.055 12.8 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain KR PF08659.10 RLN92347.1 - 0.055 13.4 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 KR domain ADH_N PF08240.12 RLN92348.1 - 6.1e-25 87.2 3.1 1.2e-24 86.3 3.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN92348.1 - 4.3e-17 62.3 0.3 7.3e-17 61.6 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN92348.1 - 2.9e-08 34.8 0.0 4.3e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN92348.1 - 0.00071 19.0 0.1 0.0012 18.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN92348.1 - 0.0027 17.0 0.4 0.0045 16.3 0.4 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TAFII28 PF04719.14 RLN92349.1 - 5.6e-16 58.4 0.1 9.2e-16 57.7 0.1 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region DUF2722 PF10846.8 RLN92349.1 - 0.06 12.3 5.8 0.071 12.0 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Myc_N PF01056.18 RLN92349.1 - 0.068 13.1 5.4 0.083 12.8 5.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Nop14 PF04147.12 RLN92349.1 - 0.091 11.0 16.6 0.1 10.8 16.6 1.0 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 RLN92349.1 - 0.18 11.8 5.7 0.27 11.3 5.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Sporozoite_P67 PF05642.11 RLN92349.1 - 0.22 9.6 3.7 0.21 9.7 3.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RPN2_C PF18004.1 RLN92349.1 - 0.32 10.9 4.7 0.4 10.6 4.7 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RNA_polI_A34 PF08208.11 RLN92349.1 - 0.46 10.5 8.2 0.61 10.1 8.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SAPS PF04499.15 RLN92349.1 - 0.53 9.0 4.3 0.61 8.8 4.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 RLN92349.1 - 0.74 9.2 15.5 0.89 8.9 15.5 1.1 1 0 0 1 1 1 0 SDA1 TFIIA PF03153.13 RLN92349.1 - 0.87 9.5 11.0 1.1 9.1 11.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 RLN92349.1 - 1 7.6 12.7 1.2 7.4 12.7 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 RLN92349.1 - 1 8.6 15.6 1.1 8.5 15.6 1.1 1 0 0 1 1 1 0 BUD22 DUF913 PF06025.12 RLN92349.1 - 1.7 7.5 4.1 2.2 7.2 4.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NOA36 PF06524.12 RLN92349.1 - 1.9 7.7 14.1 2.8 7.2 14.1 1.2 1 0 0 1 1 1 0 NOA36 protein LAP1C PF05609.12 RLN92349.1 - 2.3 7.2 10.0 2.8 6.9 10.0 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) UPF0524 PF15823.5 RLN92349.1 - 2.7 7.3 6.2 3.7 6.9 6.2 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 XAP5 PF04921.14 RLN92349.1 - 4.2 7.1 9.5 5.7 6.7 9.5 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF3336 PF11815.8 RLN92350.1 - 1.9e-21 76.2 0.3 3.2e-21 75.5 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 RLN92350.1 - 1.4e-17 64.6 0.1 2.2e-16 60.7 0.1 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase SdpI PF13630.6 RLN92350.1 - 0.56 10.4 2.7 10 6.4 0.0 2.9 2 0 0 2 2 2 0 SdpI/YhfL protein family Rootletin PF15035.6 RLN92353.1 - 0.0011 19.0 10.5 0.0022 18.1 10.5 1.5 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Atg14 PF10186.9 RLN92353.1 - 0.0038 16.3 11.3 0.0063 15.6 11.3 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 zf-Nse PF11789.8 RLN92353.1 - 0.0068 16.2 0.2 0.015 15.1 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit AAA_16 PF13191.6 RLN92353.1 - 0.029 14.8 5.4 0.64 10.4 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain C1_1 PF00130.22 RLN92353.1 - 0.57 10.1 5.6 1.2 9.1 5.6 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DASH_Spc34 PF08657.10 RLN92353.1 - 0.78 9.5 7.7 1.3 8.7 7.7 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 Exonuc_VII_L PF02601.15 RLN92353.1 - 0.86 9.1 7.9 1.6 8.2 7.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit CHD5 PF04420.14 RLN92353.1 - 3.8 7.4 7.9 7.5 6.4 7.9 1.4 1 0 0 1 1 1 0 CHD5-like protein DUF4407 PF14362.6 RLN92353.1 - 6 6.1 8.9 11 5.3 8.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 RLN92353.1 - 8.7 6.4 16.9 15 5.6 16.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus QRPTase_C PF01729.19 RLN92354.1 - 3.1e-56 189.8 0.0 3.8e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 RLN92354.1 - 8.4e-17 61.0 0.0 2.3e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain RRM_2 PF04059.12 RLN92355.1 - 8.9e-45 150.8 0.8 1.4e-44 150.2 0.8 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 zf-B_box PF00643.24 RLN92355.1 - 0.00053 20.1 9.5 0.0012 19.0 9.5 1.5 1 0 0 1 1 1 1 B-box zinc finger Smg4_UPF3 PF03467.15 RLN92355.1 - 0.0039 17.2 0.1 0.0079 16.2 0.1 1.5 1 0 0 1 1 1 1 Smg-4/UPF3 family RRM_1 PF00076.22 RLN92355.1 - 0.019 14.8 0.0 0.1 12.4 0.1 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 RLN92355.1 - 0.12 12.4 0.0 6.2 6.9 0.0 2.4 2 0 0 2 2 2 0 RL domain BRAP2 PF07576.12 RLN92355.1 - 0.12 12.6 0.2 0.3 11.3 0.2 1.6 1 0 0 1 1 1 0 BRCA1-associated protein 2 ZZ PF00569.17 RLN92355.1 - 0.46 10.3 6.6 1 9.2 6.6 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type PriCT_2 PF08707.11 RLN92355.1 - 1.5 9.2 4.8 2.1 8.8 1.4 2.4 2 0 0 2 2 2 0 Primase C terminal 2 (PriCT-2) TetR_C_11 PF16859.5 RLN92356.1 - 0.077 13.3 0.5 0.077 13.3 0.5 4.1 4 1 1 5 5 5 0 Tetracyclin repressor-like, C-terminal domain SNF2_N PF00176.23 RLN92357.1 - 4.3e-51 173.7 0.1 6.6e-50 169.8 0.1 2.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN92357.1 - 5.4e-16 58.9 0.0 1.5e-15 57.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PHD PF00628.29 RLN92357.1 - 1.7e-09 37.5 2.9 1.7e-09 37.5 2.9 3.5 4 0 0 4 4 4 1 PHD-finger zf-C3HC4_3 PF13920.6 RLN92357.1 - 1e-06 28.5 5.0 1e-06 28.5 5.0 3.5 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN92357.1 - 3.4e-06 26.8 5.3 3.4e-06 26.8 5.3 3.3 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN92357.1 - 1e-05 25.3 2.9 1e-05 25.3 2.9 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 RLN92357.1 - 1.4e-05 25.2 0.5 0.00014 21.9 0.0 2.6 2 1 0 2 2 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 RLN92357.1 - 2.7e-05 24.4 18.6 0.00032 21.0 5.9 2.9 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 RLN92357.1 - 5.9e-05 22.9 5.4 5.9e-05 22.9 5.4 3.6 5 0 0 5 5 4 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RLN92357.1 - 6.8e-05 22.8 3.5 6.8e-05 22.8 3.5 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 RLN92357.1 - 0.0021 18.3 9.9 0.071 13.4 2.0 2.8 2 0 0 2 2 2 2 RING-H2 zinc finger domain zf-BED PF02892.15 RLN92357.1 - 0.28 11.3 4.1 0.21 11.6 0.1 2.9 3 0 0 3 3 2 0 BED zinc finger Zn_Tnp_IS91 PF14319.6 RLN92357.1 - 0.32 11.0 4.1 0.79 9.8 1.0 3.1 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-C2HC_2 PF13913.6 RLN92357.1 - 0.4 10.6 6.8 0.36 10.8 0.1 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-HC5HC2H PF13771.6 RLN92357.1 - 2.4 8.5 10.7 0.66 10.3 1.1 3.1 3 0 0 3 3 2 0 PHD-like zinc-binding domain Zn_ribbon_17 PF17120.5 RLN92357.1 - 4.6 6.9 9.4 0.9 9.2 0.6 2.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 RLN92357.1 - 5.5 7.3 7.3 12 6.1 0.8 3.0 2 0 0 2 2 2 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 RLN92357.1 - 9.3 6.4 7.2 13 5.9 0.8 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF572 PF04502.13 RLN92358.1 - 1.2e-57 196.0 0.0 1.4e-57 195.8 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf_PR_Knuckle PF18445.1 RLN92358.1 - 7.3 6.5 5.8 0.74 9.7 0.3 2.1 3 0 0 3 3 3 0 PR zinc knuckle motif PBP_sp32 PF07222.12 RLN92359.1 - 1.6 8.2 7.1 7.7 5.9 0.5 2.1 2 0 0 2 2 2 0 Proacrosin binding protein sp32 Presenilin PF01080.17 RLN92359.1 - 8.5 5.0 6.2 12 4.6 6.2 1.2 1 0 0 1 1 1 0 Presenilin PPC PF04151.15 RLN92360.1 - 2.6 9.2 6.7 3.3 8.9 0.3 3.0 3 1 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain DHC_N2 PF08393.13 RLN92361.1 - 6e-57 193.5 0.6 6e-57 193.5 0.6 3.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 RLN92361.1 - 1.8e-24 86.2 0.0 7.8e-24 84.2 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_6 PF12774.7 RLN92361.1 - 2e-24 86.2 1.6 2.3e-20 72.8 0.0 2.8 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region MT PF12777.7 RLN92361.1 - 3.2e-24 85.6 0.2 6.4e-24 84.6 0.2 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.7 RLN92361.1 - 6.8e-07 28.9 0.0 1.4e-05 24.6 0.0 2.5 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_16 PF13191.6 RLN92361.1 - 0.00029 21.3 0.1 0.042 14.2 0.1 4.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RLN92361.1 - 0.0049 17.1 0.0 0.032 14.5 0.0 2.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 RLN92361.1 - 0.056 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Dynein_AAA_lid PF17852.1 RLN92361.1 - 0.28 11.3 3.8 0.53 10.4 0.0 3.5 3 0 0 3 3 3 0 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RLN92361.1 - 0.57 10.2 2.4 1.3 9.0 0.1 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DP PF08781.10 RLN92361.1 - 0.61 10.0 6.4 2.1 8.3 6.4 1.9 1 0 0 1 1 1 0 Transcription factor DP DUF4148 PF13663.6 RLN92361.1 - 1.8 8.8 4.4 25 5.1 3.3 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) PAP_central PF04928.17 RLN92362.1 - 5.1e-19 68.2 0.1 1.9e-16 59.8 0.0 2.0 1 1 1 2 2 2 2 Poly(A) polymerase central domain Glyco_hydro_17 PF00332.18 RLN92363.1 - 2.3e-05 24.1 1.9 5.5e-05 22.9 1.9 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 WD40 PF00400.32 RLN92364.1 - 1.1e-05 26.0 0.3 0.31 12.0 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Pkinase PF00069.25 RLN92365.1 - 3.7e-77 259.3 0.0 4.8e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92365.1 - 1.8e-36 125.7 0.0 2.3e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN92365.1 - 4.1e-05 23.0 0.3 7.3e-05 22.2 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN92365.1 - 0.0033 17.4 0.5 0.12 12.3 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 RLN92365.1 - 0.0076 15.9 0.2 0.013 15.2 0.2 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 RLN92365.1 - 0.02 14.2 0.0 0.037 13.3 0.0 1.7 1 1 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.9 RLN92365.1 - 0.021 14.3 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 RLN92365.1 - 0.023 13.5 0.0 0.045 12.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase OrfB_Zn_ribbon PF07282.11 RLN92370.1 - 0.0079 16.1 2.7 0.024 14.5 2.7 1.8 1 0 0 1 1 1 1 Putative transposase DNA-binding domain DZR PF12773.7 RLN92370.1 - 0.084 12.9 0.8 0.21 11.7 0.8 1.6 1 0 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS91 PF14319.6 RLN92370.1 - 0.36 10.9 4.6 0.29 11.2 2.2 2.2 1 1 0 1 1 1 0 Transposase zinc-binding domain zf-ribbon_3 PF13248.6 RLN92370.1 - 0.37 10.3 6.6 2.5 7.6 0.8 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 RLN92370.1 - 2.2 8.3 4.8 12 6.0 4.8 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-Mss51 PF13824.6 RLN92370.1 - 2.4 8.3 8.0 9.4 6.4 3.8 2.8 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_2 PF13240.6 RLN92370.1 - 3.5 7.5 5.6 11 5.9 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain YhfH PF14149.6 RLN92370.1 - 7.3 6.7 9.4 1.5 8.8 0.2 2.9 2 1 1 3 3 3 0 YhfH-like protein Zn-ribbon_8 PF09723.10 RLN92371.1 - 3.5e-05 23.8 1.9 4.7e-05 23.4 1.9 1.2 1 0 0 1 1 1 1 Zinc ribbon domain HypA PF01155.19 RLN92371.1 - 0.00079 19.4 0.2 0.00089 19.3 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 RLN92371.1 - 0.0017 18.4 0.3 0.0023 17.9 0.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 RLN92371.1 - 0.0059 16.5 0.6 0.17 11.9 0.0 2.1 2 0 0 2 2 2 1 Transposase zinc-ribbon domain NOB1_Zn_bind PF08772.11 RLN92371.1 - 0.0075 16.4 0.1 0.0091 16.1 0.1 1.1 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-RING_4 PF14570.6 RLN92371.1 - 0.016 15.0 1.1 3.1 7.6 0.1 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-FPG_IleRS PF06827.14 RLN92371.1 - 0.02 14.8 2.2 0.59 10.1 0.1 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zinc_ribbon_2 PF13240.6 RLN92371.1 - 0.025 14.3 1.8 0.18 11.6 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 RLN92371.1 - 0.033 13.6 0.9 0.092 12.2 0.0 2.0 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 RLN92371.1 - 0.041 13.8 3.2 2.7 8.0 0.6 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 RLN92371.1 - 0.054 13.4 1.2 5.4 7.0 0.1 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2_4 PF13894.6 RLN92371.1 - 0.07 14.0 3.7 1.5 9.9 0.4 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 RLN92371.1 - 0.077 13.5 3.6 1.1 9.9 0.8 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-trcl PF13451.6 RLN92371.1 - 0.092 12.6 4.4 1.5 8.8 0.3 2.1 1 1 1 2 2 2 0 Probable zinc-ribbon domain LIM PF00412.22 RLN92371.1 - 0.094 13.0 2.4 0.15 12.3 2.4 1.3 1 1 0 1 1 1 0 LIM domain zinc_ribbon_9 PF14369.6 RLN92371.1 - 1.5 9.2 7.5 5.3 7.4 5.2 2.3 2 1 1 3 3 3 0 zinc-ribbon zinc_ribbon_10 PF10058.9 RLN92371.1 - 2.4 7.9 5.1 31 4.4 5.1 2.1 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Rubredoxin_2 PF18073.1 RLN92371.1 - 4.9 7.0 7.0 13 5.6 0.2 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain Pkinase PF00069.25 RLN92373.1 - 0.00054 19.4 0.1 0.004 16.6 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92373.1 - 0.00072 18.9 0.1 0.0024 17.2 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase OrfB_IS605 PF01385.19 RLN92374.1 - 0.097 12.9 0.6 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 Probable transposase WH2 PF02205.20 RLN92375.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 WH2 motif PAE PF03283.13 RLN92376.1 - 1.1e-12 47.7 0.6 2.1e-12 46.8 0.6 1.4 1 1 0 1 1 1 1 Pectinacetylesterase DUF2235 PF09994.9 RLN92376.1 - 0.0029 17.0 0.0 0.021 14.2 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_3 PF07859.13 RLN92376.1 - 0.12 12.2 0.0 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold LCM PF04072.14 RLN92377.1 - 1.8e-37 129.2 0.0 2.2e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase THF_DHG_CYH PF00763.23 RLN92377.1 - 0.054 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain G-patch PF01585.23 RLN92378.1 - 5.4e-11 42.2 1.9 5.4e-11 42.2 1.9 1.7 2 0 0 2 2 2 1 G-patch domain adh_short PF00106.25 RLN92378.1 - 7.4e-07 28.8 0.0 1.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase G-patch_2 PF12656.7 RLN92378.1 - 2.6e-06 27.4 0.7 4.6e-06 26.6 0.7 1.4 1 0 0 1 1 1 1 G-patch domain Eno-Rase_NADH_b PF12242.8 RLN92378.1 - 0.0027 17.5 0.1 0.0056 16.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.10 RLN92378.1 - 0.012 15.6 0.4 0.022 14.7 0.1 1.6 2 0 0 2 2 2 0 KR domain Pkinase_Tyr PF07714.17 RLN92379.1 - 1.8e-59 201.2 0.0 6.9e-44 150.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN92379.1 - 1e-50 172.6 0.0 1.6e-37 129.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 RLN92379.1 - 0.0011 18.3 0.0 0.28 10.4 0.0 2.7 2 1 0 2 2 2 2 Kinase-like HEAT_2 PF13646.6 RLN92379.1 - 0.0046 17.3 0.6 0.022 15.1 0.1 2.4 2 0 0 2 2 2 1 HEAT repeats Arm PF00514.23 RLN92379.1 - 0.019 15.0 0.1 0.38 10.9 0.0 2.8 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat MoaE PF02391.17 RLN92379.1 - 0.025 14.9 0.0 3.3 8.0 0.0 3.2 3 0 0 3 3 3 0 MoaE protein Kdo PF06293.14 RLN92379.1 - 0.068 12.5 0.0 2.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN92379.1 - 1.1 9.1 7.9 1.2 9.0 0.0 3.6 4 0 0 4 4 4 0 Phosphotransferase enzyme family EMP70 PF02990.16 RLN92381.1 - 1.3e-41 142.9 1.8 1.6e-41 142.6 1.8 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 LRR_4 PF12799.7 RLN92383.1 - 0.00015 22.1 3.6 0.034 14.6 0.1 3.6 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN92383.1 - 0.0012 18.5 3.4 0.0029 17.3 0.4 2.8 3 1 0 3 3 3 1 Leucine rich repeat BSD PF03909.17 RLN92384.1 - 1.3e-08 34.7 0.0 3.1e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 BSD domain Rhodanese PF00581.20 RLN92385.1 - 0.0001 22.8 0.0 0.00041 20.8 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain DUF1378 PF07125.11 RLN92385.1 - 0.21 11.8 0.7 0.72 10.1 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1378) AhpC-TSA PF00578.21 RLN92386.1 - 4.1e-38 130.1 0.1 5.4e-38 129.7 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RLN92386.1 - 2.1e-16 59.9 0.0 3.1e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 RLN92386.1 - 7.1e-12 45.0 0.0 1.5e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 RLN92386.1 - 0.025 14.5 0.2 0.075 12.9 0.2 1.7 2 0 0 2 2 2 0 SCO1/SenC DNA_pol_B_exo1 PF03104.19 RLN92387.1 - 5.2e-72 242.8 0.0 7.8e-72 242.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 RLN92387.1 - 1.5e-16 60.2 0.3 8.5e-14 51.1 0.3 3.3 3 0 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 RLN92387.1 - 1.2e-08 34.9 0.1 3e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 RLN92387.1 - 1.6e-07 31.4 0.3 9e-07 29.0 0.0 2.4 2 1 0 2 2 2 1 RNase_H superfamily Transcrip_reg PF01709.20 RLN92388.1 - 2.1e-38 132.1 0.0 2.6e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator RuvX PF03652.15 RLN92389.1 - 0.0025 18.2 0.5 0.0052 17.2 0.5 1.4 1 0 0 1 1 1 1 Holliday junction resolvase Nop25 PF09805.9 RLN92389.1 - 0.037 14.5 2.3 0.15 12.5 2.3 2.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF2218 PF09981.9 RLN92389.1 - 0.058 13.8 1.6 1.9 8.9 0.4 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2218) adh_short_C2 PF13561.6 RLN92392.1 - 5.4e-51 173.4 2.4 6.6e-51 173.1 2.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RLN92392.1 - 1.1e-45 155.5 1.8 1.5e-45 155.1 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RLN92392.1 - 5.5e-11 42.7 0.5 7.7e-11 42.2 0.5 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 RLN92392.1 - 2.4e-05 23.6 0.0 3.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 RLN92392.1 - 0.0013 18.3 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Pyr_redox PF00070.27 RLN92392.1 - 0.0013 19.2 0.2 0.0042 17.6 0.2 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 RLN92392.1 - 0.0039 16.7 0.3 0.0092 15.5 0.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 RLN92392.1 - 0.014 15.9 0.2 0.029 14.8 0.2 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 RLN92392.1 - 0.044 13.0 0.2 0.13 11.5 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SIS PF01380.22 RLN92392.1 - 0.067 13.0 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 SIS domain RmlD_sub_bind PF04321.17 RLN92392.1 - 0.093 11.8 0.2 0.18 10.9 0.2 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain 3HCDH_N PF02737.18 RLN92392.1 - 0.32 10.9 2.9 0.3 11.0 1.0 2.0 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thioesterase PF00975.20 RLN92393.1 - 4e-18 66.4 0.0 5.8e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 RLN92393.1 - 3.1e-07 30.6 0.1 1.6e-06 28.4 0.1 2.3 1 1 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 RLN92393.1 - 0.0036 17.9 1.2 0.0036 17.9 1.2 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family ASH PF15780.5 RLN92394.1 - 7.8e-18 64.5 0.2 1.4e-16 60.5 0.1 2.9 2 1 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CH PF00307.31 RLN92394.1 - 3.4e-16 59.4 0.1 4.1e-06 26.9 0.0 4.2 4 0 0 4 4 4 3 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RLN92394.1 - 6.2e-06 26.0 0.7 0.00036 20.3 0.1 4.0 4 0 0 4 4 4 1 CAMSAP CH domain Ribosomal_60s PF00428.19 RLN92395.1 - 1.2e-15 57.8 4.9 1.7e-15 57.4 4.9 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Prog_receptor PF02161.15 RLN92395.1 - 0.012 14.4 1.9 0.014 14.2 1.9 1.1 1 0 0 1 1 1 0 Progesterone receptor MAP17 PF15807.5 RLN92396.1 - 0.46 10.7 3.4 0.63 10.3 0.4 2.7 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 INTS2 PF14750.6 RLN92398.1 - 8.9e-14 50.1 5.0 2.1e-05 22.3 1.0 3.8 4 1 0 4 4 4 3 Integrator complex subunit 2 EF-hand_5 PF13202.6 RLN92400.1 - 5e-05 22.6 0.0 0.00014 21.2 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 RLN92400.1 - 0.00087 18.7 0.0 0.0041 16.6 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RLN92400.1 - 0.0085 16.0 0.0 0.029 14.3 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain UL73_N PF12522.8 RLN92400.1 - 0.017 14.8 11.2 0.017 14.8 11.2 2.5 2 0 0 2 2 2 0 Cytomegalovirus glycoprotein N terminal EF-hand_7 PF13499.6 RLN92400.1 - 0.14 12.6 0.0 0.36 11.3 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair DUF3446 PF11928.8 RLN92400.1 - 0.49 10.7 4.6 1.1 9.6 0.1 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain Gtr1_RagA PF04670.12 RLN92402.1 - 1.6e-57 194.5 0.9 2.4e-57 193.9 0.2 1.6 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 RLN92402.1 - 0.085 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DnaJ PF00226.31 RLN92403.1 - 1.9e-27 95.2 1.6 3.2e-27 94.4 1.6 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 RLN92403.1 - 1.2e-23 83.8 0.0 1.8e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain LprI PF07007.12 RLN92403.1 - 0.13 12.9 0.2 0.87 10.3 0.0 2.1 2 0 0 2 2 2 0 Lysozyme inhibitor LprI SVIP PF15811.5 RLN92404.1 - 2.7e-05 24.5 6.5 2.7e-05 24.5 6.5 2.1 2 0 0 2 2 2 2 Small VCP/p97-interacting protein CBS PF00571.28 RLN92405.1 - 1.2e-17 64.1 0.1 3.9e-07 30.4 0.0 4.3 3 1 1 4 4 4 4 CBS domain Syntaxin PF00804.25 RLN92406.1 - 2.1e-30 105.9 2.4 3.4e-30 105.2 2.4 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 RLN92406.1 - 1.3e-16 60.3 0.3 3.6e-16 58.9 0.3 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 RLN92406.1 - 0.0024 18.2 1.9 0.0024 18.2 1.9 2.2 2 1 0 2 2 2 1 Syntaxin-like protein OmpA_membrane PF01389.17 RLN92406.1 - 0.031 14.0 0.1 5.2 6.8 0.1 2.2 2 0 0 2 2 2 0 OmpA-like transmembrane domain Pepsin-I3 PF06394.13 RLN92406.1 - 0.062 13.5 0.4 0.17 12.1 0.1 1.8 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain LCE6A PF15858.5 RLN92406.1 - 0.066 14.0 0.0 0.19 12.5 0.0 1.7 1 0 0 1 1 1 0 Late cornified envelope protein 6A family PAH PF02671.21 RLN92406.1 - 0.07 13.3 1.3 0.07 13.3 1.3 2.0 2 0 0 2 2 2 0 Paired amphipathic helix repeat KIP1 PF07765.12 RLN92406.1 - 0.18 12.0 1.7 2.9 8.1 0.2 2.7 2 1 0 2 2 2 0 KIP1-like protein YscO-like PF16789.5 RLN92406.1 - 0.25 11.4 11.1 0.15 12.1 5.2 2.2 2 0 0 2 2 2 0 YscO-like protein Spore_III_AB PF09548.10 RLN92406.1 - 0.78 9.8 5.1 0.17 12.0 0.7 2.1 2 2 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) CHCH PF06747.13 RLN92407.1 - 2.1e-08 34.1 4.2 3e-08 33.6 4.2 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 RLN92407.1 - 0.0021 18.0 2.3 0.0032 17.5 2.3 1.2 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX6B PF02297.17 RLN92407.1 - 0.035 14.3 1.7 0.051 13.8 1.7 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb MTCP1 PF08991.10 RLN92407.1 - 0.051 13.8 2.8 0.091 13.0 2.8 1.4 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type Amino_oxidase PF01593.24 RLN92408.1 - 2.2e-53 182.2 0.5 1e-51 176.7 0.5 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RLN92408.1 - 3.4e-10 40.0 0.2 1.5e-09 37.9 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 RLN92408.1 - 1.8e-06 26.9 1.5 0.00026 19.8 0.7 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 RLN92408.1 - 2e-06 27.2 0.2 0.00024 20.5 0.2 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 RLN92408.1 - 3.7e-05 23.0 1.1 6.5e-05 22.2 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 RLN92408.1 - 0.00019 21.9 1.2 0.0029 18.1 0.8 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RLN92408.1 - 0.0012 18.5 2.9 0.0012 18.5 2.9 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 RLN92408.1 - 0.0036 16.5 0.2 0.0036 16.5 0.2 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 RLN92408.1 - 0.0059 15.9 0.2 0.011 15.0 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 RLN92408.1 - 0.0081 15.3 3.7 0.0085 15.2 1.7 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 RLN92408.1 - 0.021 14.8 0.4 0.25 11.3 0.1 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 RLN92408.1 - 0.086 12.2 0.7 0.41 9.9 0.7 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 RLN92408.1 - 0.13 11.6 0.5 0.22 10.8 0.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 RLN92408.1 - 0.17 11.1 1.1 0.28 10.4 0.4 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RLN92408.1 - 1.1 8.5 3.7 0.45 9.7 0.9 1.7 2 0 0 2 2 2 0 FAD binding domain Mg_trans_NIPA PF05653.14 RLN92409.1 - 5.1e-14 52.1 13.2 6.1e-14 51.8 13.2 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 RLN92409.1 - 0.0021 18.2 4.9 0.0021 18.2 4.9 2.9 2 1 0 2 2 2 1 EamA-like transporter family DUF3619 PF12279.8 RLN92409.1 - 0.27 11.6 0.8 0.57 10.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) DUF2993 PF11209.8 RLN92410.1 - 0.023 15.0 0.2 0.032 14.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2993) H_lectin PF09458.10 RLN92410.1 - 0.09 13.0 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 H-type lectin domain PUF PF00806.19 RLN92411.1 - 2.8e-63 206.2 11.3 2e-08 33.5 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 RLN92411.1 - 7.8e-06 26.3 0.5 2.7 8.3 0.0 4.7 3 1 2 5 5 5 3 CPL (NUC119) domain sCache_2 PF17200.4 RLN92411.1 - 0.012 15.4 0.2 9.3 6.1 0.0 4.0 4 1 1 5 5 5 0 Single Cache domain 2 ACBP PF00887.19 RLN92412.1 - 1.8e-28 98.5 5.3 2.2e-28 98.3 5.3 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein GAF PF01590.26 RLN92413.1 - 4.5e-07 30.6 0.0 9.5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 GAF domain Macoilin PF09726.9 RLN92413.1 - 1.2 7.6 7.4 1.6 7.2 7.4 1.1 1 0 0 1 1 1 0 Macoilin family PAN_1 PF00024.26 RLN92414.1 - 2.4e-10 40.2 0.5 4.1e-10 39.5 0.5 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 RLN92414.1 - 1.5e-08 34.4 2.1 1.5e-08 34.4 2.1 2.1 2 1 0 2 2 2 1 PAN domain KRTAP7 PF15034.6 RLN92414.1 - 0.1 13.6 6.6 0.79 10.7 0.2 2.2 2 0 0 2 2 2 0 KRTAP type 7 family PAN_1 PF00024.26 RLN92415.1 - 1.5e-11 44.0 0.3 2.9e-11 43.2 0.3 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 RLN92415.1 - 1.8e-09 37.4 2.2 1.8e-09 37.4 2.2 2.2 2 0 0 2 2 2 1 PAN domain PAN_1 PF00024.26 RLN92416.1 - 3.6e-21 74.9 11.7 2e-11 43.7 1.6 2.8 2 1 0 2 2 2 2 PAN domain PAN_4 PF14295.6 RLN92416.1 - 6.4e-19 67.6 10.8 2.5e-10 40.1 1.1 3.8 4 0 0 4 4 4 2 PAN domain PAN_2 PF08276.11 RLN92416.1 - 0.029 14.5 0.8 0.029 14.5 0.8 3.0 3 0 0 3 3 3 0 PAN-like domain Granulin PF00396.18 RLN92416.1 - 0.05 13.9 7.1 0.05 13.9 7.1 4.0 4 0 0 4 4 4 0 Granulin Carn_acyltransf PF00755.20 RLN92417.1 - 3.3e-125 419.0 0.0 3.8e-125 418.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase PDEase_I PF00233.19 RLN92418.1 - 3.3e-29 102.3 0.7 5.7e-29 101.5 0.7 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 RLN92418.1 - 1.2e-08 35.7 0.2 1.1e-07 32.6 0.0 2.4 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 RLN92418.1 - 5.3e-05 23.5 0.0 0.00027 21.3 0.0 2.3 2 0 0 2 2 2 1 GAF domain TetR_C_30 PF17939.1 RLN92418.1 - 0.046 13.9 0.5 6.3 7.1 0.0 3.7 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain PX PF00787.24 RLN92420.1 - 0.00021 21.2 0.0 0.00054 19.9 0.0 1.6 1 1 0 1 1 1 1 PX domain TMF_TATA_bd PF12325.8 RLN92421.1 - 0.011 16.0 8.2 0.011 16.0 8.2 5.0 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding RasGEF_N_2 PF14663.6 RLN92421.1 - 0.061 13.7 0.8 0.061 13.7 0.8 3.0 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF1664 PF07889.12 RLN92421.1 - 0.14 12.2 23.1 0.29 11.2 0.2 4.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Lipoprotein_7 PF01540.16 RLN92421.1 - 0.21 10.9 1.9 0.25 10.6 0.9 1.6 1 1 0 1 1 1 0 Adhesin lipoprotein FlaC_arch PF05377.11 RLN92421.1 - 2.1 8.8 13.1 7.6 7.0 0.5 5.1 4 1 2 6 6 6 0 Flagella accessory protein C (FlaC) DUF4574 PF15141.6 RLN92421.1 - 5.3 7.0 9.6 0.27 11.2 1.3 3.0 2 2 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 4HB_MCP_1 PF12729.7 RLN92421.1 - 5.5 6.5 9.0 0.88 9.1 2.5 2.5 2 1 0 2 2 2 0 Four helix bundle sensory module for signal transduction TetR_C_12 PF16914.5 RLN92421.1 - 6.6 6.9 7.6 11 6.2 2.5 3.0 2 1 1 3 3 3 0 Bacterial transcriptional repressor C-terminal DUF4605 PF15378.6 RLN92422.1 - 0.0017 18.1 1.6 0.0017 18.1 1.6 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4605) cNMP_binding PF00027.29 RLN92423.1 - 0.0064 16.5 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Acetate_kinase PF00871.17 RLN92425.1 - 3.4e-138 460.6 0.1 4e-138 460.4 0.1 1.0 1 0 0 1 1 1 1 Acetokinase family DUSP PF06337.12 RLN92426.1 - 8.8e-08 32.7 0.0 2.7e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 DUSP domain MBT PF02820.18 RLN92426.1 - 0.0012 19.2 0.0 0.0022 18.3 0.0 1.4 1 0 0 1 1 1 1 mbt repeat Tudor-knot PF11717.8 RLN92426.1 - 0.0088 15.9 0.3 0.027 14.4 0.3 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Tudor_4 PF18358.1 RLN92426.1 - 0.034 13.8 0.3 0.19 11.3 0.3 2.3 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain DUF1818 PF08848.11 RLN92426.1 - 0.24 11.5 5.1 0.36 10.9 2.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1818) DUF4835 PF16119.5 RLN92426.1 - 3.9 6.5 8.5 1.6 7.8 5.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4835) PCRF PF03462.18 RLN92427.1 - 5.4e-54 183.0 0.1 1.1e-53 181.9 0.1 1.5 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 RLN92427.1 - 1.7e-37 127.9 0.8 1.7e-37 127.9 0.8 2.1 2 0 0 2 2 2 1 RF-1 domain DUF572 PF04502.13 RLN92427.1 - 2.9 7.4 9.9 4.3 6.9 9.9 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF572) CBF PF03914.17 RLN92428.1 - 7.6e-56 188.8 1.0 3e-54 183.6 0.1 3.0 2 0 0 2 2 2 1 CBF/Mak21 family DUF913 PF06025.12 RLN92428.1 - 0.0095 15.0 0.2 0.0095 15.0 0.2 2.9 3 1 0 3 3 3 1 Domain of Unknown Function (DUF913) Cnd1 PF12717.7 RLN92428.1 - 0.033 14.2 0.0 0.087 12.9 0.0 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 AAA_22 PF13401.6 RLN92428.1 - 0.79 10.0 2.7 0.89 9.8 0.1 2.4 3 0 0 3 3 3 0 AAA domain Cadherin_C PF01049.17 RLN92429.1 - 0.031 14.6 0.1 0.066 13.6 0.1 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic region TssO PF17561.2 RLN92429.1 - 2.7 8.1 5.8 1.4 9.0 0.3 2.5 2 1 1 3 3 3 0 Type VI secretion system, TssO Chromo PF00385.24 RLN92431.1 - 1.6e-05 24.7 0.5 3.2e-05 23.7 0.5 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain YhhN PF07947.14 RLN92431.1 - 0.0091 15.6 5.4 0.015 14.9 5.4 1.3 1 0 0 1 1 1 1 YhhN family Nucleoporin_C PF03177.14 RLN92432.1 - 6.2e-08 31.8 2.2 1.8e-05 23.7 1.7 3.0 2 1 1 3 3 3 3 Non-repetitive/WGA-negative nucleoporin C-terminal Cullin PF00888.22 RLN92433.1 - 8.3e-172 573.0 2.9 1e-171 572.7 2.9 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 RLN92433.1 - 2.2e-18 66.1 2.8 2.2e-18 66.1 2.8 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain eIF-6 PF01912.18 RLN92433.1 - 0.13 11.6 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 eIF-6 family AMP-binding PF00501.28 RLN92435.1 - 1.6e-73 247.7 0.0 2.2e-73 247.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 RLN92435.1 - 3.7e-11 43.2 0.1 4.9e-10 39.6 0.2 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site TILa PF12714.7 RLN92437.1 - 7.8 6.5 29.1 0.4 10.7 10.7 3.3 1 1 2 3 3 3 0 TILa domain GH131_N PF18271.1 RLN92438.1 - 2.7e-48 164.9 0.1 3.6e-48 164.5 0.1 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain GH131_N PF18271.1 RLN92439.1 - 4.5e-48 164.2 0.1 5.5e-48 163.9 0.1 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain DUF3640 PF12342.8 RLN92440.1 - 0.02 14.6 0.1 0.046 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3640) GH131_N PF18271.1 RLN92440.1 - 0.038 13.7 0.0 0.042 13.5 0.0 1.1 1 0 0 1 1 1 0 Glycoside hydrolase 131 catalytic N-terminal domain TrbC PF04956.13 RLN92440.1 - 0.044 14.0 0.1 0.053 13.8 0.1 1.2 1 0 0 1 1 1 0 TrbC/VIRB2 family DnaJ PF00226.31 RLN92442.1 - 5.2e-21 74.5 1.8 1.3e-20 73.3 0.1 2.3 2 0 0 2 2 2 1 DnaJ domain AAA_23 PF13476.6 RLN92442.1 - 0.056 13.9 3.3 0.063 13.8 3.3 1.2 1 0 0 1 1 1 0 AAA domain ZT_dimer PF16916.5 RLN92443.1 - 3.6e-12 46.2 0.4 7.2e-12 45.3 0.4 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Cation_efflux PF01545.21 RLN92443.1 - 1.3e-05 25.1 0.3 1.6e-05 24.7 0.3 1.1 1 0 0 1 1 1 1 Cation efflux family UPRTase PF14681.6 RLN92444.1 - 4.1e-23 81.9 0.2 7.1e-23 81.1 0.2 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HTH_7 PF02796.15 RLN92444.1 - 0.072 13.2 0.1 0.25 11.5 0.2 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase adh_short PF00106.25 RLN92445.1 - 4.8e-29 101.2 1.7 9.6e-14 51.3 0.0 2.5 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN92445.1 - 2e-18 66.9 2.7 3.2e-10 39.9 0.2 2.6 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 RLN92445.1 - 8.8e-16 58.2 0.1 1.9e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family KR PF08659.10 RLN92445.1 - 7.7e-06 25.9 0.7 0.012 15.6 0.2 2.3 2 0 0 2 2 2 2 KR domain Alkyl_sulf_C PF14864.6 RLN92445.1 - 0.065 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal AdoHcyase_NAD PF00670.21 RLN92445.1 - 0.11 12.5 0.5 0.24 11.4 0.5 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain CbiA PF01656.23 RLN92445.1 - 0.19 11.8 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain eIF3_N PF09440.10 RLN92446.1 - 2.1e-19 70.2 1.0 2.7e-19 69.9 1.0 1.1 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain LRR_6 PF13516.6 RLN92447.1 - 3.3e-11 42.3 14.8 0.018 15.0 0.0 7.5 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 RLN92447.1 - 1.2e-08 35.1 4.8 0.26 11.8 0.0 6.8 2 1 5 9 9 9 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN92447.1 - 8.7e-07 28.6 10.7 0.35 10.6 0.0 7.0 5 2 3 8 8 8 3 Leucine rich repeat LRR_1 PF00560.33 RLN92447.1 - 0.018 15.5 10.7 20 6.3 0.1 6.7 6 2 0 6 6 6 0 Leucine Rich Repeat IMUP PF15761.5 RLN92447.1 - 0.15 12.8 4.0 0.28 11.9 4.0 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein LRR_9 PF14580.6 RLN92447.1 - 0.15 11.5 1.3 0.73 9.3 0.1 2.4 2 1 0 2 2 2 0 Leucine-rich repeat SR-25 PF10500.9 RLN92447.1 - 0.22 11.1 2.1 0.33 10.5 2.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tup_N PF08581.10 RLN92448.1 - 0.011 16.1 1.1 0.011 16.1 1.1 5.9 3 2 2 5 5 5 0 Tup N-terminal SlyX PF04102.12 RLN92448.1 - 0.017 15.8 0.8 0.017 15.8 0.8 6.8 5 2 1 7 7 7 0 SlyX RskA PF10099.9 RLN92448.1 - 0.081 13.2 0.2 3.2 8.0 0.0 2.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DNA_primase_lrg PF04104.14 RLN92449.1 - 7.8e-76 255.0 0.9 1.1e-75 254.5 0.1 1.5 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit PMSR PF01625.21 RLN92452.1 - 5e-60 202.1 1.2 5e-60 202.1 1.2 1.8 2 0 0 2 2 2 1 Peptide methionine sulfoxide reductase SPRY PF00622.28 RLN92452.1 - 8.5e-17 61.4 0.1 3.4e-16 59.4 0.0 2.1 3 0 0 3 3 3 1 SPRY domain Neuralized PF07177.12 RLN92452.1 - 0.0092 16.0 0.0 0.022 14.8 0.0 1.7 2 0 0 2 2 2 1 Neuralized PK_C PF02887.16 RLN92452.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain CCT PF06203.14 RLN92453.1 - 2.8e-11 43.3 5.5 4.4e-11 42.6 5.5 1.3 1 0 0 1 1 1 1 CCT motif DUF285 PF03382.14 RLN92453.1 - 0.00016 21.4 3.2 0.0051 16.6 0.5 2.7 1 1 2 3 3 3 2 Mycoplasma protein of unknown function, DUF285 FATC PF02260.20 RLN92453.1 - 0.062 13.1 0.0 16 5.4 0.0 2.9 3 0 0 3 3 3 0 FATC domain Sec1 PF00995.23 RLN92454.1 - 2.2e-95 321.1 0.1 5.3e-95 319.8 0.0 1.6 2 0 0 2 2 2 1 Sec1 family DrsE PF02635.15 RLN92454.1 - 0.012 16.0 0.0 0.039 14.3 0.0 1.9 1 0 0 1 1 1 0 DsrE/DsrF-like family LPP PF04728.13 RLN92454.1 - 0.11 12.8 1.1 0.88 10.0 1.1 2.6 1 0 0 1 1 1 0 Lipoprotein leucine-zipper MCU PF04678.13 RLN92454.1 - 0.61 10.2 8.3 0.27 11.3 0.3 3.0 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF2536 PF10750.9 RLN92454.1 - 0.73 9.8 6.0 0.65 9.9 1.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) Snapin_Pallidin PF14712.6 RLN92454.1 - 0.83 10.1 10.0 3.9 8.0 4.5 3.8 1 1 1 2 2 2 0 Snapin/Pallidin DUF4131 PF13567.6 RLN92454.1 - 1.2 8.8 3.3 5.4 6.6 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Fez1 PF06818.15 RLN92454.1 - 3.2 8.2 8.3 14 6.1 8.2 2.2 1 1 0 1 1 1 0 Fez1 TMF_TATA_bd PF12325.8 RLN92454.1 - 3.8 7.8 10.7 2.5 8.4 6.0 3.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.21 RLN92454.1 - 4.9 7.3 8.9 2.6 8.2 1.1 3.8 3 0 0 3 3 3 0 bZIP transcription factor DUF16 PF01519.16 RLN92454.1 - 7.5 7.1 6.6 25 5.4 1.5 3.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUSP PF06337.12 RLN92455.1 - 2.4e-08 34.5 0.0 3.9e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 DUSP domain PDZ PF00595.24 RLN92455.1 - 0.072 13.4 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Pkinase PF00069.25 RLN92456.1 - 7.4e-80 268.1 0.0 9.1e-80 267.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92456.1 - 5.3e-34 117.7 0.0 7.8e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN92456.1 - 8.1e-05 22.1 0.0 0.0094 15.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 RLN92456.1 - 0.00062 19.2 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN92456.1 - 0.012 15.6 2.4 2.6 7.9 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pre-PUA PF17832.1 RLN92457.1 - 3.1e-10 40.6 0.2 5.7e-10 39.8 0.2 1.5 1 0 0 1 1 1 1 Pre-PUA-like domain Pre-PUA PF17832.1 RLN92458.1 - 2.8e-09 37.5 0.1 3.7e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 RLN92458.1 - 7e-07 29.1 0.0 1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 PUA domain MatC_N PF07158.11 RLN92458.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Dicarboxylate carrier protein MatC N-terminus DUF1947 PF09183.10 RLN92458.1 - 0.21 11.9 0.0 0.29 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) AMIN PF11741.8 RLN92460.1 - 0.00035 20.6 0.6 25 5.1 0.0 4.5 4 0 0 4 4 4 3 AMIN domain NADH_dh_m_C1 PF15088.6 RLN92460.1 - 0.013 15.1 25.0 3.8 7.2 0.1 7.2 8 0 0 8 8 8 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial PRKG1_interact PF15898.5 RLN92462.1 - 0.15 13.0 0.1 0.15 13.0 0.1 2.6 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain UTP15_C PF09384.10 RLN92463.1 - 0.0069 16.1 0.1 0.017 14.8 0.1 1.6 1 0 0 1 1 1 1 UTP15 C terminal DUF4130 PF13566.6 RLN92463.1 - 0.066 13.3 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4130 BATS PF06968.13 RLN92463.1 - 0.15 12.2 0.1 30 4.8 0.1 2.6 2 0 0 2 2 2 0 Biotin and Thiamin Synthesis associated domain ANAPC4_WD40 PF12894.7 RLN92464.1 - 0.023 15.0 0.0 26 5.2 0.0 3.7 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_16 PF10294.9 RLN92466.1 - 1.6e-23 83.3 0.0 2.4e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PDZ PF00595.24 RLN92467.1 - 2.8e-06 27.6 0.2 0.0097 16.2 0.1 2.6 3 0 0 3 3 3 2 PDZ domain DUSP PF06337.12 RLN92467.1 - 0.00038 21.0 0.0 0.00077 20.0 0.0 1.5 1 0 0 1 1 1 1 DUSP domain DUF1491 PF07372.12 RLN92467.1 - 0.026 14.9 0.1 0.27 11.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1491) PDZ_6 PF17820.1 RLN92467.1 - 0.056 13.3 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Ank_4 PF13637.6 RLN92468.1 - 1.6e-20 73.2 11.4 1.3e-07 32.0 0.1 6.2 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN92468.1 - 2.3e-14 53.2 8.1 0.00016 21.9 0.1 6.1 2 1 4 7 7 7 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN92468.1 - 5.9e-14 52.4 1.6 5.5e-05 23.7 0.1 3.5 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN92468.1 - 5.1e-06 26.4 2.8 15 6.6 0.0 6.5 8 0 0 8 8 8 1 Ankyrin repeat Ank PF00023.30 RLN92468.1 - 0.095 13.2 2.8 33 5.1 0.2 5.0 4 2 0 4 4 4 0 Ankyrin repeat UPF0489 PF12640.7 RLN92468.1 - 0.22 11.8 1.3 1.7 8.8 0.1 2.9 2 1 0 2 2 2 0 UPF0489 domain zf-CW PF07496.15 RLN92469.1 - 7.9e-42 141.0 45.4 3.6e-16 58.9 9.2 4.5 4 0 0 4 4 4 3 CW-type Zinc Finger PHD PF00628.29 RLN92469.1 - 1.3e-10 41.0 36.0 2.9e-07 30.3 0.3 6.7 6 0 0 6 6 6 4 PHD-finger zf-RING_2 PF13639.6 RLN92469.1 - 0.016 15.5 22.7 0.16 12.4 0.5 3.8 3 0 0 3 3 3 0 Ring finger domain adh_short PF00106.25 RLN92470.1 - 5.4e-100 332.7 0.2 1.5e-53 181.2 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN92470.1 - 1.4e-69 234.2 0.1 8.2e-37 127.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN92470.1 - 3.1e-27 95.7 4.3 1e-12 48.4 0.6 2.5 3 0 0 3 3 3 2 KR domain Epimerase PF01370.21 RLN92470.1 - 1e-05 25.2 1.1 0.095 12.1 0.2 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family YccV-like PF08755.11 RLN92470.1 - 0.021 15.3 0.0 0.79 10.3 0.0 2.3 2 0 0 2 2 2 0 Hemimethylated DNA-binding protein YccV like zf-RING_2 PF13639.6 RLN92471.1 - 2.1e-10 40.8 12.2 3.4e-10 40.1 12.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RLN92471.1 - 1.5e-08 34.7 9.2 3.6e-08 33.6 9.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 RLN92471.1 - 1.7e-05 24.4 7.2 3.1e-05 23.6 7.2 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 RLN92471.1 - 4.6e-05 23.2 9.5 7.8e-05 22.5 9.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN92471.1 - 7.5e-05 22.7 7.5 0.00014 21.8 7.5 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RLN92471.1 - 0.00019 21.3 12.1 0.00029 20.6 12.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN92471.1 - 0.00022 21.0 12.5 0.00034 20.4 12.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN92471.1 - 0.00068 19.5 9.7 0.0012 18.8 9.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-HC5HC2H PF13771.6 RLN92471.1 - 0.001 19.3 3.5 0.0021 18.3 3.5 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain Zn_ribbon_17 PF17120.5 RLN92471.1 - 0.0049 16.5 7.6 0.0084 15.7 7.6 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-HC5HC2H_2 PF13832.6 RLN92471.1 - 0.02 15.1 3.0 0.043 14.0 3.0 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-ANAPC11 PF12861.7 RLN92471.1 - 0.022 14.8 7.2 0.056 13.5 7.2 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 RLN92471.1 - 0.052 13.4 8.9 0.098 12.5 8.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 RLN92471.1 - 0.074 13.2 6.1 0.18 12.0 6.1 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 RLN92471.1 - 0.086 13.2 9.8 0.14 12.5 9.8 1.3 1 0 0 1 1 1 0 RING-like domain DASH_Hsk3 PF08227.11 RLN92471.1 - 0.16 12.4 2.2 0.29 11.5 2.2 1.4 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like Pet100 PF09803.9 RLN92471.1 - 0.19 12.2 0.1 0.58 10.7 0.1 1.8 1 0 0 1 1 1 0 Pet100 C1_2 PF03107.16 RLN92471.1 - 1.2 9.5 4.6 0.23 11.8 1.1 1.6 2 0 0 2 2 1 0 C1 domain RINGv PF12906.7 RLN92471.1 - 1.8 8.7 11.2 3.6 7.8 11.2 1.4 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 RLN92471.1 - 2.1 8.4 4.7 4.4 7.4 4.7 1.5 1 0 0 1 1 1 0 Zinc-finger zf-RING_4 PF14570.6 RLN92471.1 - 7 6.5 8.0 15 5.5 7.9 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 RLN92471.1 - 9.9 6.2 9.2 16 5.5 9.2 1.4 1 0 0 1 1 1 0 PHD-finger T3SSipB PF16535.5 RLN92477.1 - 0.0053 17.3 0.6 0.0053 17.3 0.6 2.6 2 0 0 2 2 2 1 Type III cell invasion protein SipB Phage_Mu_Gam PF07352.12 RLN92477.1 - 0.06 13.3 8.7 0.61 10.0 1.6 2.6 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein Aminotran_1_2 PF00155.21 RLN92477.1 - 0.28 10.3 3.7 0.11 11.6 0.3 1.8 2 0 0 2 2 2 0 Aminotransferase class I and II BMFP PF04380.13 RLN92477.1 - 1.2 9.7 9.5 0.88 10.1 0.8 2.8 2 0 0 2 2 2 0 Membrane fusogenic activity DUF1084 PF06454.11 RLN92478.1 - 1.9 7.8 19.1 0.022 14.1 2.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1084) DNA_pol_B_thumb PF14791.6 RLN92479.1 - 1.3e-19 70.1 0.5 3.4e-19 68.8 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 RLN92479.1 - 1.6e-19 69.5 0.0 4.1e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda XK-related PF09815.9 RLN92479.1 - 2.2e-07 30.3 6.9 3.2e-07 29.7 6.9 1.2 1 0 0 1 1 1 1 XK-related protein HHH_5 PF14520.6 RLN92479.1 - 0.00066 20.2 0.0 0.0029 18.2 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain Med8 PF10232.9 RLN92479.1 - 0.0036 16.9 4.1 0.0058 16.2 4.1 1.3 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Cdd1 PF11731.8 RLN92479.1 - 0.017 15.4 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus DUF2052 PF09747.9 RLN92479.1 - 0.19 11.9 13.3 0.35 11.0 13.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Nup54_57_C PF18570.1 RLN92480.1 - 0.012 15.2 2.0 0.18 11.4 0.0 2.8 2 1 1 3 3 3 0 NUP57/Nup54 C-terminal domain p450 PF00067.22 RLN92481.1 - 0.0029 16.4 0.1 0.0063 15.3 0.1 1.5 1 0 0 1 1 1 1 Cytochrome P450 FGGY_N PF00370.21 RLN92485.1 - 5.1e-72 242.4 0.0 8.4e-72 241.7 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 RLN92485.1 - 5.8e-64 215.5 0.8 8.9e-64 214.9 0.8 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Mito_carr PF00153.27 RLN92486.1 - 8.9e-66 217.9 0.6 4.7e-21 74.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 RLN92486.1 - 0.02 14.1 1.4 0.21 10.7 0.7 2.7 2 1 0 2 2 2 0 Gammaproteobacterial serine protease Jnk-SapK_ap_N PF09744.9 RLN92487.1 - 1.3 9.2 13.8 2.9 8.1 13.8 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Mito_carr PF00153.27 RLN92489.1 - 1.4e-65 217.2 3.0 8.3e-21 73.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 RLN92489.1 - 0.057 13.5 1.9 3.5 7.8 0.0 3.2 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif HSF_DNA-bind PF00447.17 RLN92491.1 - 7.8e-21 74.5 1.8 1.1e-20 74.0 1.8 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding HSF_DNA-bind PF00447.17 RLN92492.1 - 3.3e-20 72.5 0.6 4.7e-20 72.0 0.6 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding MtmB PF05369.12 RLN92492.1 - 0.15 10.8 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB DUF900 PF05990.12 RLN92493.1 - 4.3e-06 26.4 0.0 6.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) MORN PF02493.20 RLN92493.1 - 0.23 11.4 1.1 26 5.0 0.3 3.6 3 0 0 3 3 3 0 MORN repeat TctB PF07331.11 RLN92493.1 - 0.44 10.8 10.1 0.88 9.8 10.1 1.4 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family FGF-BP1 PF06473.12 RLN92494.1 - 0.61 9.9 5.6 1.2 9.0 5.6 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Abhydrolase_1 PF00561.20 RLN92495.1 - 0.015 15.0 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Actin PF00022.19 RLN92496.1 - 1.5e-144 481.6 0.0 4.9e-144 479.9 0.0 1.7 1 1 0 1 1 1 1 Actin Ribosomal_L11_N PF03946.14 RLN92497.1 - 5.2e-25 87.1 1.3 2.7e-24 84.8 0.2 2.2 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 RLN92497.1 - 9.6e-23 80.5 0.1 1.8e-22 79.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Scs3p PF10261.9 RLN92497.1 - 0.0012 18.4 5.8 0.0027 17.2 5.9 1.5 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Peptidase_C1 PF00112.23 RLN92498.1 - 1.2e-73 247.8 1.6 1.7e-73 247.4 1.6 1.2 1 0 0 1 1 1 1 Papain family cysteine protease E1_DerP2_DerF2 PF02221.15 RLN92498.1 - 6.6e-14 52.5 0.0 1.1e-13 51.8 0.0 1.4 1 0 0 1 1 1 1 ML domain Inhibitor_I29 PF08246.12 RLN92498.1 - 8.1e-09 35.8 0.8 1.4e-08 35.0 0.8 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 RLN92498.1 - 0.0013 17.6 3.6 0.042 12.6 0.1 2.4 3 0 0 3 3 3 2 Peptidase C1-like family zf-C3HC4_4 PF15227.6 RLN92499.1 - 0.0031 17.6 2.8 0.042 14.0 1.3 3.0 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 RLN92499.1 - 0.023 14.7 6.9 0.27 11.3 1.7 3.0 3 0 0 3 3 3 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RLN92499.1 - 0.05 13.5 2.4 1.3 9.0 0.1 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN92499.1 - 0.06 13.2 6.8 0.42 10.5 0.2 3.9 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN92499.1 - 0.9 9.5 4.0 2.7 7.9 0.2 3.2 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) AAA_6 PF12774.7 RLN92500.1 - 1.1e-154 514.3 0.0 9e-153 508.0 0.0 2.9 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 RLN92500.1 - 3.1e-104 348.5 0.0 9.2e-104 346.9 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 RLN92500.1 - 1e-97 326.6 0.0 2.5e-97 325.3 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RLN92500.1 - 1.6e-83 279.2 0.0 7.3e-83 277.0 0.0 2.2 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 RLN92500.1 - 1.1e-81 272.6 0.0 1.7e-77 259.0 0.0 3.5 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RLN92500.1 - 9e-54 181.7 0.1 1.8e-53 180.7 0.1 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RLN92500.1 - 2e-46 157.0 0.0 1.8e-42 144.2 0.0 3.1 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 RLN92500.1 - 8.7e-45 153.2 12.7 1.4e-44 152.6 12.7 1.2 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 RLN92500.1 - 5.4e-33 113.8 0.0 1.6e-32 112.3 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RLN92500.1 - 8.4e-23 80.5 0.2 7.8e-22 77.4 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 RLN92500.1 - 2.9e-20 72.7 0.0 1.1e-05 25.5 0.0 5.5 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RLN92500.1 - 4.5e-05 23.7 0.0 4.5 7.5 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 RLN92500.1 - 0.0008 19.2 0.8 4.1 7.1 0.1 3.4 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 RLN92500.1 - 0.001 18.2 0.4 0.09 11.8 0.0 3.2 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_18 PF13238.6 RLN92500.1 - 0.0016 19.0 0.0 0.085 13.4 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 RLN92500.1 - 0.0023 18.4 0.3 0.64 10.5 0.1 3.5 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 RLN92500.1 - 0.0053 16.2 1.8 0.71 9.2 0.0 3.8 5 0 0 5 5 4 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 RLN92500.1 - 0.0074 16.7 9.0 4.6 7.6 0.0 5.8 6 0 0 6 6 5 1 AAA ATPase domain DUF87 PF01935.17 RLN92500.1 - 0.014 15.5 0.4 1.4 8.9 0.1 3.2 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 RLN92500.1 - 0.019 15.4 0.0 2.9 8.3 0.0 3.3 3 0 0 3 3 3 0 RNA helicase SRP54 PF00448.22 RLN92500.1 - 0.021 14.4 3.2 21 4.6 0.0 3.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.18 RLN92500.1 - 0.068 12.5 0.3 3.8 6.8 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.6 RLN92500.1 - 0.073 13.4 4.1 1.6 9.0 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 RLN92500.1 - 0.11 12.7 0.3 19 5.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain DUF853 PF05872.12 RLN92500.1 - 0.14 10.7 16.6 0.38 9.3 0.1 4.0 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF853) AAA_24 PF13479.6 RLN92500.1 - 0.2 11.4 0.1 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 RLN92500.1 - 0.27 10.0 1.4 6 5.6 0.5 2.3 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Spc7 PF08317.11 RLN92500.1 - 0.33 9.8 14.6 0.8 8.5 2.9 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein Filament PF00038.21 RLN92500.1 - 0.59 9.7 9.9 0.49 9.9 1.6 2.4 2 0 0 2 2 2 0 Intermediate filament protein DUF745 PF05335.13 RLN92500.1 - 0.64 9.7 22.8 1.1 9.0 5.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Laminin_II PF06009.12 RLN92500.1 - 1.2 9.2 14.4 3.8 7.5 3.7 2.8 2 1 0 2 2 2 0 Laminin Domain II MscS_porin PF12795.7 RLN92500.1 - 1.4 8.4 16.8 0.0094 15.5 4.6 2.5 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain TrwB_AAD_bind PF10412.9 RLN92500.1 - 2.1 7.2 8.2 0.95 8.3 0.1 3.4 4 0 0 4 4 3 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 RLN92500.1 - 5.3 6.3 6.9 39 3.4 0.1 4.2 5 0 0 5 5 5 0 Zeta toxin ATG16 PF08614.11 RLN92500.1 - 5.4 7.2 12.2 2 8.6 2.8 2.6 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) B56 PF01603.20 RLN92501.1 - 4.3e-13 49.0 0.0 6.1e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Pkinase PF00069.25 RLN92502.1 - 5.1e-41 140.8 0.0 6.9e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92502.1 - 5.8e-33 114.3 0.0 8.6e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase hEGF PF12661.7 RLN92502.1 - 0.0005 20.6 129.9 0.015 15.9 7.9 12.8 12 0 0 12 12 12 7 Human growth factor-like EGF Haspin_kinase PF12330.8 RLN92502.1 - 0.001 18.1 0.0 0.0015 17.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain EGF PF00008.27 RLN92502.1 - 0.0047 17.2 31.1 0.0095 16.2 13.0 12.3 12 0 0 12 12 12 5 EGF-like domain APH PF01636.23 RLN92502.1 - 0.061 13.2 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN92502.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN92502.1 - 0.17 10.6 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase BBS1 PF14779.6 RLN92504.1 - 1.3e-41 142.8 0.0 3.4e-41 141.4 0.0 1.6 1 1 0 1 1 1 1 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.6 RLN92504.1 - 0.015 15.3 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region baeRF_family8 PF18851.1 RLN92504.1 - 0.067 13.3 0.0 8.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 8 HypA PF01155.19 RLN92505.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 RLN92506.1 - 2.4e-06 27.3 5.7 0.0031 17.4 0.6 2.2 1 1 1 2 2 2 2 Putative transposase DNA-binding domain Efg1 PF10153.9 RLN92510.1 - 0.00056 20.2 1.9 0.001 19.4 1.9 1.4 1 0 0 1 1 1 1 rRNA-processing protein Efg1 HNH_4 PF13395.6 RLN92510.1 - 0.042 13.8 0.7 1.3 9.0 0.0 2.8 2 1 1 3 3 3 0 HNH endonuclease DUF465 PF04325.13 RLN92510.1 - 0.48 10.5 4.4 5.2 7.2 1.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Phage_int_SAM_4 PF13495.6 RLN92511.1 - 0.0048 17.3 0.0 0.0078 16.7 0.0 1.4 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain SPRY PF00622.28 RLN92512.1 - 4.8e-07 29.9 0.3 3.4e-06 27.2 0.1 2.3 2 1 0 2 2 2 1 SPRY domain PP2C PF00481.21 RLN92513.1 - 3.8e-38 131.6 0.0 2.5e-37 128.9 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C COMM_domain PF07258.14 RLN92514.1 - 9.1e-15 54.5 0.3 1.3e-14 54.1 0.3 1.2 1 0 0 1 1 1 1 COMM domain TIP41 PF04176.13 RLN92515.1 - 3.1e-57 192.8 0.5 4.3e-57 192.4 0.5 1.2 1 0 0 1 1 1 1 TIP41-like family ASCH PF04266.14 RLN92516.1 - 0.00012 22.6 0.0 0.00027 21.5 0.0 1.5 1 1 0 1 1 1 1 ASCH domain Pkinase PF00069.25 RLN92517.1 - 1.1e-34 120.0 0.0 1.7e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92517.1 - 3.6e-15 56.0 0.0 2.9e-13 49.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN92517.1 - 0.0022 17.3 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RLN92517.1 - 0.022 13.5 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 RLN92517.1 - 0.025 14.5 1.3 0.055 13.4 1.3 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN92517.1 - 0.031 13.6 0.0 0.084 12.2 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5521 PF17659.1 RLN92518.1 - 2.5e-06 25.7 0.0 6.3e-06 24.4 0.0 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF5521) DIX PF00778.17 RLN92518.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 DIX domain Rep-A_N PF04057.12 RLN92518.1 - 0.15 12.1 0.0 0.69 10.0 0.0 2.0 2 0 0 2 2 2 0 Replication factor-A protein 1, N-terminal domain CK_II_beta PF01214.18 RLN92519.1 - 4.6e-77 258.0 0.1 6.3e-77 257.5 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit SDA1 PF05285.12 RLN92519.1 - 0.004 16.7 5.0 0.004 16.7 5.0 1.5 2 0 0 2 2 2 1 SDA1 DUF2457 PF10446.9 RLN92519.1 - 0.11 11.6 18.6 0.17 11.0 18.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FYDLN_acid PF09538.10 RLN92519.1 - 0.12 13.1 14.6 0.29 11.8 12.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) RRN3 PF05327.11 RLN92519.1 - 0.26 9.8 4.8 0.32 9.5 4.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Rhabdo_ncap PF00945.18 RLN92519.1 - 0.34 9.7 6.0 0.48 9.2 6.0 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein CobT PF06213.12 RLN92519.1 - 0.39 10.1 11.0 0.57 9.5 11.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CENP-B_dimeris PF09026.10 RLN92519.1 - 0.43 11.0 16.5 1 9.8 16.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pox_Ag35 PF03286.14 RLN92519.1 - 0.48 10.2 8.0 0.84 9.4 8.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.6 RLN92519.1 - 0.76 9.4 7.9 1.4 8.6 7.9 1.4 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 RLN92519.1 - 0.83 7.7 17.9 1.1 7.3 17.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 RLN92519.1 - 0.88 8.8 10.1 1.3 8.3 10.1 1.2 1 0 0 1 1 1 0 BUD22 Nop53 PF07767.11 RLN92519.1 - 2.1 7.6 11.9 3.1 7.1 11.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Sigma70_ner PF04546.13 RLN92519.1 - 2.4 8.0 12.5 4.2 7.2 12.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.6 RLN92519.1 - 2.8 8.4 10.5 0.6 10.5 6.9 1.7 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.12 RLN92519.1 - 4.9 5.2 14.9 7.5 4.6 14.9 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RLN92519.1 - 5 5.3 12.9 7.2 4.8 12.9 1.1 1 0 0 1 1 1 0 CDC45-like protein EF-hand_8 PF13833.6 RLN92521.1 - 5.1e-14 51.9 3.0 2.7e-10 39.9 0.7 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 RLN92521.1 - 7.5e-14 51.9 0.3 1.7e-12 47.6 0.6 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN92521.1 - 3.7e-13 48.0 7.5 3.8e-07 29.2 1.1 3.2 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 RLN92521.1 - 3.4e-11 42.1 3.0 0.00012 21.7 0.1 3.5 3 1 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 RLN92521.1 - 7.7e-05 22.0 6.4 0.042 13.3 0.6 3.5 3 1 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 RLN92521.1 - 0.00063 20.0 0.1 0.0011 19.3 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 RLN92521.1 - 0.064 13.2 0.7 0.16 11.9 0.6 1.8 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Thiolase_N PF00108.23 RLN92523.1 - 4.2e-81 272.1 1.7 4.2e-81 272.1 1.7 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RLN92523.1 - 4.5e-20 71.5 0.3 1.8e-19 69.6 0.1 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 RLN92523.1 - 0.00014 21.6 5.6 0.0012 18.5 0.9 3.4 3 1 1 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 RLN92523.1 - 0.093 12.6 1.7 3.5 7.5 0.1 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III TUDOR_5 PF18359.1 RLN92525.1 - 8.2e-50 166.3 40.6 3.2e-06 26.7 0.3 10.4 10 0 0 10 10 10 9 Histone methyltransferase Tudor domain 1 DUF1325 PF07039.11 RLN92525.1 - 1.9e-29 102.4 8.8 0.011 15.8 0.0 9.1 4 3 4 9 9 9 7 SGF29 tudor-like domain Agenet PF05641.12 RLN92525.1 - 3.7e-28 97.8 25.1 0.0078 16.7 0.0 10.9 11 0 0 11 11 11 10 Agenet domain DUF4537 PF15057.6 RLN92525.1 - 2.5e-19 69.5 4.9 0.04 13.9 0.0 8.5 3 3 5 8 8 8 7 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 RLN92525.1 - 2.7e-13 49.5 29.5 0.28 11.0 0.3 9.7 10 0 0 10 10 10 7 Lamin-B receptor of TUDOR domain 53-BP1_Tudor PF09038.10 RLN92525.1 - 3.4e-11 43.2 24.1 0.3 11.0 0.0 9.7 6 3 5 11 11 11 5 Tumour suppressor p53-binding protein-1 Tudor Bac_A_amyl_C PF18612.1 RLN92525.1 - 0.037 13.8 8.1 60 3.5 0.1 5.9 6 0 0 6 6 6 0 Bacterial Alpha amylase C-terminal domain DUF2729 PF10870.8 RLN92525.1 - 0.069 13.0 3.1 1.8e+02 2.1 0.0 5.3 5 0 0 5 5 5 0 Protein of unknown function (DUF2729) DUF1541 PF07563.11 RLN92525.1 - 1.7 8.6 5.4 15 5.6 0.1 5.0 8 0 0 8 8 8 0 Protein of unknown function (DUF1541) DUF3221 PF11518.8 RLN92525.1 - 2.4 8.6 12.9 39 4.7 0.1 5.7 7 0 0 7 7 7 0 Protein of unknown function (DUF3221) DUF4681 PF15732.5 RLN92525.1 - 3.4 8.0 14.3 22 5.4 0.8 5.2 6 0 0 6 6 6 0 Domain of unknown function (DUF4681) SH3_13 PF18335.1 RLN92525.1 - 5.9 6.8 6.2 94 2.9 0.0 4.7 6 0 0 6 6 6 0 ATP-dependent RecD-like DNA helicase SH3 domain Orn_Arg_deC_N PF02784.16 RLN92526.1 - 0.0059 16.0 0.1 0.009 15.4 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain B56 PF01603.20 RLN92526.1 - 0.18 10.7 0.0 0.34 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DFRP_C PF16543.5 RLN92527.1 - 4.3 7.9 0.0 4.3 7.9 0.0 5.9 6 1 2 8 8 8 0 DRG Family Regulatory Proteins, Tma46 Exo_endo_phos PF03372.23 RLN92528.1 - 1.6e-10 40.9 1.1 2.1e-10 40.5 1.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CN_hydrolase PF00795.22 RLN92528.1 - 0.054 12.8 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase Methyltr_RsmB-F PF01189.17 RLN92530.1 - 1.1e-17 64.3 0.0 4.5e-17 62.3 0.0 2.1 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Trypsin_2 PF13365.6 RLN92532.1 - 1.1e-05 26.3 0.0 1.9e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF3824 PF12868.7 RLN92532.1 - 0.21 12.3 1.5 0.35 11.5 1.5 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) TPR_16 PF13432.6 RLN92533.1 - 2.2e-08 34.6 52.3 0.00022 21.8 0.7 11.3 14 0 0 14 14 12 4 Tetratricopeptide repeat TPR_8 PF13181.6 RLN92533.1 - 4.3e-07 29.6 37.4 0.12 12.6 0.2 13.4 15 0 0 15 15 14 3 Tetratricopeptide repeat TPR_17 PF13431.6 RLN92533.1 - 2.1e-05 24.6 21.7 0.0059 16.9 0.1 10.7 12 0 0 12 12 11 1 Tetratricopeptide repeat BTAD PF03704.17 RLN92533.1 - 0.00054 20.4 13.8 0.0072 16.8 1.5 4.9 5 1 0 5 5 4 1 Bacterial transcriptional activator domain TPR_12 PF13424.6 RLN92533.1 - 0.00095 19.4 47.2 0.27 11.6 1.1 12.2 14 2 1 15 15 14 4 Tetratricopeptide repeat TPR_11 PF13414.6 RLN92533.1 - 0.0025 17.5 25.0 0.19 11.5 0.0 9.4 11 0 0 11 11 10 2 TPR repeat Sel1 PF08238.12 RLN92533.1 - 0.0052 17.4 3.2 0.45 11.3 0.0 4.7 4 0 0 4 4 4 1 Sel1 repeat Vps39_1 PF10366.9 RLN92533.1 - 0.0063 16.8 1.2 4.6 7.6 0.1 4.0 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 TPR_7 PF13176.6 RLN92533.1 - 0.0069 16.3 15.7 0.5 10.5 0.6 7.6 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN92533.1 - 0.024 15.4 51.0 2.7 9.0 0.1 14.5 13 3 3 16 16 13 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN92533.1 - 0.024 14.7 61.1 0.25 11.5 0.6 14.8 18 0 0 18 18 15 0 Tetratricopeptide repeat FIST_C PF10442.9 RLN92533.1 - 0.031 14.3 0.1 0.27 11.2 0.0 2.6 2 0 0 2 2 2 0 FIST C domain ANAPC3 PF12895.7 RLN92533.1 - 0.2 11.9 31.2 0.51 10.6 0.1 8.9 9 1 1 10 10 10 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 RLN92533.1 - 0.25 12.1 30.9 0.09 13.4 0.8 7.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN92533.1 - 0.55 10.1 52.7 0.16 11.9 0.1 13.7 17 0 0 17 17 17 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN92533.1 - 1 9.9 48.9 0.25 11.9 0.2 10.4 11 2 0 11 11 10 0 Tetratricopeptide repeat TPR_9 PF13371.6 RLN92533.1 - 6.4 7.0 10.9 17 5.7 1.7 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat ThiF PF00899.21 RLN92534.1 - 1e-38 133.1 0.5 6.6e-38 130.5 0.1 1.9 1 1 0 2 2 2 1 ThiF family TrkA_N PF02254.18 RLN92534.1 - 0.01 16.1 0.4 0.089 13.1 0.0 2.7 3 0 0 3 3 3 0 TrkA-N domain Ldh_1_N PF00056.23 RLN92534.1 - 0.035 14.2 0.0 0.072 13.2 0.0 1.7 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 RLN92534.1 - 0.047 12.9 0.3 0.083 12.1 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 RLN92534.1 - 0.056 13.7 1.5 0.29 11.4 1.5 2.2 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 RLN92534.1 - 0.092 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TipAS PF07739.13 RLN92534.1 - 0.13 12.8 0.1 0.65 10.6 0.0 2.2 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Hydrolase_like PF13242.6 RLN92535.1 - 3.4e-17 62.2 0.1 1.1e-15 57.4 0.0 2.7 2 1 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 RLN92535.1 - 4.7e-08 33.1 4.6 0.0018 18.4 0.0 3.1 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 RLN92535.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase WD40 PF00400.32 RLN92537.1 - 4.9e-12 46.2 15.4 0.002 18.9 0.1 6.1 3 2 3 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN92537.1 - 2.4e-08 34.2 0.4 0.04 14.2 0.0 4.3 3 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RLN92537.1 - 0.00011 22.1 0.4 8.2 6.3 0.0 4.1 3 2 2 5 5 5 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 RLN92537.1 - 0.0021 17.9 0.0 0.51 10.3 0.0 3.2 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat SET PF00856.28 RLN92538.1 - 2.1e-08 34.7 0.0 5.7e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 SET domain SseC PF04888.12 RLN92538.1 - 0.058 13.0 0.1 0.68 9.5 0.0 2.0 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family DDE_1 PF03184.19 RLN92540.1 - 7e-13 48.6 0.0 1.1e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease CENP-B_N PF04218.13 RLN92540.1 - 2.4e-05 23.9 0.4 4.5e-05 23.0 0.4 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc5 PF03221.16 RLN92540.1 - 0.00036 20.5 0.0 0.00084 19.3 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.6 RLN92540.1 - 0.0079 16.3 0.0 0.023 14.8 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 RLN92540.1 - 0.069 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain GntR PF00392.21 RLN92540.1 - 0.1 12.3 0.0 0.36 10.5 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_38 PF13936.6 RLN92540.1 - 0.16 11.7 0.2 0.4 10.5 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Ribonuc_P_40 PF08584.11 RLN92541.1 - 1.7e-71 240.8 0.0 2e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit PP2C PF00481.21 RLN92545.1 - 1e-18 67.9 0.0 1.2e-18 67.7 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 RLN92545.1 - 0.046 13.6 0.0 0.055 13.4 0.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) GGACT PF06094.12 RLN92546.1 - 2e-20 73.6 0.7 2.7e-20 73.2 0.7 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 RLN92546.1 - 1.9e-06 28.2 0.1 2.9e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 RLN92547.1 - 2.8e-20 73.1 0.2 4.2e-20 72.6 0.2 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 RLN92547.1 - 6.5e-05 23.2 0.0 9.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 RLN92548.1 - 1.2e-20 74.4 0.2 1.6e-20 73.9 0.2 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 RLN92548.1 - 4.3e-05 23.8 0.0 6.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family zf-CW PF07496.15 RLN92549.1 - 1.7e-17 63.1 5.6 1.7e-08 34.3 0.1 2.4 2 0 0 2 2 2 2 CW-type Zinc Finger PHD PF00628.29 RLN92549.1 - 0.069 13.0 2.7 1 9.3 0.2 2.5 2 0 0 2 2 2 0 PHD-finger AAA_2 PF07724.14 RLN92550.1 - 5e-33 114.6 1.3 3.3e-25 89.2 0.0 3.4 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 RLN92550.1 - 1.1e-12 48.5 0.1 1.1e-05 25.9 0.1 3.7 2 1 2 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RLN92550.1 - 1.7e-06 28.1 0.2 0.00085 19.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 RLN92550.1 - 8.7e-06 25.5 0.0 0.0017 18.1 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain MCM PF00493.23 RLN92550.1 - 1e-05 24.7 0.1 0.00023 20.3 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain AAA_16 PF13191.6 RLN92550.1 - 2.7e-05 24.6 2.4 0.00024 21.5 2.4 2.4 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 RLN92550.1 - 3.7e-05 23.2 1.1 0.0062 15.9 0.0 3.4 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI ClpB_D2-small PF10431.9 RLN92550.1 - 0.00031 20.7 0.1 0.0011 18.9 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_28 PF13521.6 RLN92550.1 - 0.00045 20.5 0.0 0.0011 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 RLN92550.1 - 0.0014 18.4 0.1 0.51 10.1 0.0 2.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 RLN92550.1 - 0.0018 17.5 0.0 0.004 16.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_11 PF13086.6 RLN92550.1 - 0.0032 17.3 1.8 0.0062 16.4 1.8 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RLN92550.1 - 0.004 17.7 0.0 0.018 15.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 RLN92550.1 - 0.0042 16.4 0.0 0.01 15.2 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin T2SSE PF00437.20 RLN92550.1 - 0.0057 15.8 0.1 0.013 14.6 0.1 1.6 1 1 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 RLN92550.1 - 0.0073 16.6 1.8 0.016 15.4 0.0 2.5 3 1 0 3 3 2 1 AAA domain CPT PF07931.12 RLN92550.1 - 0.011 15.6 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 RLN92550.1 - 0.011 15.9 0.0 0.04 14.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 RLN92550.1 - 0.018 14.8 0.2 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase TsaE PF02367.17 RLN92550.1 - 0.018 15.0 0.0 0.053 13.5 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.20 RLN92550.1 - 0.031 13.4 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_7 PF12775.7 RLN92550.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region FliT PF05400.13 RLN92550.1 - 4.1 8.3 8.0 0.71 10.7 1.5 2.9 3 0 0 3 3 3 0 Flagellar protein FliT Cir_N PF10197.9 RLN92551.1 - 3.6e-11 43.0 7.4 1.1e-10 41.5 7.4 1.9 1 0 0 1 1 1 1 N-terminal domain of CBF1 interacting co-repressor CIR zf-CCHC_6 PF15288.6 RLN92551.1 - 0.065 13.1 0.9 0.13 12.1 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle WD40 PF00400.32 RLN92552.1 - 4.1e-12 46.4 2.7 0.0002 22.1 0.0 5.4 5 1 0 5 5 5 2 WD domain, G-beta repeat Nbas_N PF15492.6 RLN92552.1 - 0.031 13.6 0.0 0.28 10.5 0.0 2.2 1 1 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal DUF2198 PF09964.9 RLN92553.1 - 0.08 13.0 0.4 0.08 13.0 0.4 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2198) SMC_Nse1 PF07574.13 RLN92555.1 - 2.4e-11 43.9 0.2 0.012 15.5 0.0 3.1 2 1 1 3 3 3 3 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 RLN92555.1 - 3.6e-08 33.6 6.9 5.6e-08 33.0 6.9 1.3 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 RLN92555.1 - 5.5e-06 26.6 8.0 9.2e-06 25.9 8.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H_2 PF13832.6 RLN92555.1 - 0.0023 18.1 2.5 0.0045 17.1 2.6 1.5 1 1 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RLN92555.1 - 0.0074 16.5 3.1 0.0074 16.5 3.1 1.8 1 1 1 2 2 2 1 PHD-like zinc-binding domain zf-rbx1 PF12678.7 RLN92555.1 - 0.013 15.8 3.5 0.024 14.9 3.5 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 RLN92555.1 - 0.02 14.5 5.4 0.032 13.9 5.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 RLN92555.1 - 0.047 13.6 6.0 0.53 10.2 1.3 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 RLN92555.1 - 0.077 12.9 9.6 0.11 12.3 8.3 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) C1_2 PF03107.16 RLN92555.1 - 0.086 13.2 5.7 0.21 11.9 1.0 2.3 2 0 0 2 2 2 0 C1 domain PHD PF00628.29 RLN92555.1 - 0.093 12.6 8.2 0.15 12.0 8.2 1.4 1 0 0 1 1 1 0 PHD-finger AftA_C PF12249.8 RLN92555.1 - 0.15 11.7 0.0 0.75 9.4 0.0 1.9 1 1 0 1 1 1 0 Arabinofuranosyltransferase A C terminal C1_1 PF00130.22 RLN92555.1 - 0.29 11.0 7.8 0.065 13.1 2.9 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 RLN92555.1 - 0.46 10.5 10.3 0.23 11.4 4.0 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-ribbon_3 PF13248.6 RLN92555.1 - 0.55 9.7 3.1 2.8 7.5 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_3 PF13920.6 RLN92555.1 - 1.4 8.8 10.7 22 5.0 0.5 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 RLN92555.1 - 2.1 8.6 10.2 25 5.1 10.2 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4 PF00097.25 RLN92555.1 - 2.7 8.0 9.0 4.7 7.2 9.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RLN92555.1 - 6 7.1 8.7 7.2 6.9 7.3 2.0 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 RLN92555.1 - 7.8 6.5 9.8 23 5.1 9.9 1.8 1 1 1 2 2 2 0 zinc-RING finger domain DJ-1_PfpI PF01965.24 RLN92558.1 - 8.6e-25 87.4 0.1 1e-24 87.2 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 RLN92558.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 RLN92559.1 - 2.2e-27 95.9 0.0 2.8e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family CTP_transf_1 PF01148.20 RLN92560.1 - 1.1e-36 126.9 26.6 4.9e-35 121.6 17.2 2.5 2 1 0 2 2 2 2 Cytidylyltransferase family CoatB PF10389.9 RLN92560.1 - 8.6 6.3 9.8 31 4.5 0.3 3.6 3 0 0 3 3 3 0 Bacteriophage coat protein B Pkinase PF00069.25 RLN92561.1 - 2e-59 201.1 0.0 1.5e-57 195.0 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92561.1 - 3.6e-33 114.9 0.0 2.3e-31 109.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 RLN92561.1 - 6.6e-06 25.8 0.1 1.1e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kinase-like PF14531.6 RLN92561.1 - 2.9e-05 23.5 0.0 0.00026 20.4 0.0 2.2 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RLN92561.1 - 3.2e-05 23.0 0.0 4.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 RLN92561.1 - 9.8e-05 22.0 0.3 0.00018 21.2 0.3 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 RLN92561.1 - 0.002 18.1 0.6 0.031 14.2 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN92561.1 - 0.0033 16.8 0.4 0.0057 16.0 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HHA PF05321.11 RLN92561.1 - 0.0076 16.5 0.0 5.8 7.3 0.0 2.7 2 0 0 2 2 2 2 Haemolysin expression modulating protein Pkinase_fungal PF17667.1 RLN92561.1 - 0.037 12.8 0.0 0.059 12.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 RLN92561.1 - 0.082 12.5 0.0 0.3 10.7 0.0 1.8 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 HATPase_c_5 PF14501.6 RLN92562.1 - 4.2 7.3 6.5 1.7 8.6 2.7 2.1 1 1 1 2 2 2 0 GHKL domain FtsJ PF01728.19 RLN92563.1 - 5.2e-66 222.1 0.1 6.9e-66 221.7 0.1 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 RLN92563.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DUF1287 PF06940.11 RLN92563.1 - 0.15 11.7 0.1 0.3 10.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) dCMP_cyt_deam_1 PF00383.23 RLN92564.1 - 5.2e-22 77.6 2.6 6e-22 77.4 2.6 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 RLN92564.1 - 3.5e-21 75.4 0.5 3.9e-21 75.3 0.5 1.0 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 RLN92564.1 - 5.9e-05 23.2 0.0 7.9e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 RLN92564.1 - 0.00056 20.0 0.0 0.00068 19.8 0.0 1.1 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC3 PF18771.1 RLN92564.1 - 0.00063 19.9 0.1 0.00082 19.5 0.1 1.3 1 0 0 1 1 1 1 APOBEC3 APOBEC2 PF18772.1 RLN92564.1 - 0.0011 19.1 0.0 0.0013 18.8 0.0 1.1 1 0 0 1 1 1 1 APOBEC2 Bd3614-deam PF14439.6 RLN92564.1 - 0.0032 17.5 5.4 0.049 13.7 5.4 2.0 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC_N PF08210.11 RLN92564.1 - 0.0037 17.2 0.0 0.0043 17.0 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC4_like PF18774.1 RLN92564.1 - 0.0073 16.2 0.1 0.0094 15.9 0.1 1.2 1 0 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase NAD2 PF18782.1 RLN92564.1 - 0.044 13.9 0.0 0.05 13.7 0.0 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 DUF498 PF04430.14 RLN92565.1 - 9.2e-19 67.5 0.0 1e-18 67.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) PX PF00787.24 RLN92566.1 - 8.6e-09 35.4 0.1 1.4e-08 34.7 0.1 1.3 1 0 0 1 1 1 1 PX domain PX PF00787.24 RLN92568.1 - 4.1e-08 33.2 0.0 7.3e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 PX domain TbpB_A PF17484.2 RLN92568.1 - 0.0097 16.7 0.0 0.038 14.7 0.0 2.0 1 0 0 1 1 1 1 N-Lobe handle Tf-binding protein B DUF2854 PF11016.8 RLN92568.1 - 0.071 13.0 0.2 0.33 10.8 0.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) RhoGEF PF00621.20 RLN92570.1 - 4.4e-23 82.4 0.0 6.4e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain MMR_HSR1 PF01926.23 RLN92571.1 - 7.1e-17 61.5 0.0 5.1e-14 52.3 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN92571.1 - 2.3e-07 30.5 0.0 2.4e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RLN92571.1 - 2.1e-06 27.7 0.1 0.067 13.1 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase AIG1 PF04548.16 RLN92571.1 - 0.00018 20.9 0.0 0.00032 20.1 0.0 1.3 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 RLN92571.1 - 0.00088 18.9 0.1 0.1 12.1 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 RLN92571.1 - 0.045 13.8 0.9 0.46 10.5 0.5 2.6 2 1 1 3 3 3 0 Dynamin family AAA_16 PF13191.6 RLN92571.1 - 1 9.7 0.0 1 9.7 0.0 3.8 3 2 0 3 3 3 0 AAA ATPase domain Nucleo_P87 PF07267.11 RLN92572.1 - 0.059 12.2 12.0 0.07 12.0 12.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CcmD PF04995.14 RLN92572.1 - 0.18 11.9 2.6 0.34 11.0 2.6 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Dzip-like_N PF13815.6 RLN92573.1 - 2.7e-36 124.1 3.9 2.7e-36 124.1 3.9 4.4 3 1 1 4 4 4 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2H2 PF00096.26 RLN92573.1 - 0.053 14.0 0.6 0.12 12.8 0.6 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type IQ PF00612.27 RLN92573.1 - 0.091 12.6 2.9 0.67 9.9 0.0 3.4 3 0 0 3 3 3 0 IQ calmodulin-binding motif zf-C2H2_4 PF13894.6 RLN92573.1 - 0.19 12.6 0.5 0.68 10.9 0.5 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger HALZ PF02183.18 RLN92573.1 - 8.7 6.7 16.2 0.79 10.0 0.1 3.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper DAHP_synth_1 PF00793.20 RLN92574.1 - 7.3e-47 159.5 0.1 3e-31 108.3 0.3 2.0 1 1 1 2 2 2 2 DAHP synthetase I family zf-RRPl_C4 PF17026.5 RLN92575.1 - 0.063 13.4 0.3 0.12 12.4 0.3 1.4 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type DAHP_synth_1 PF00793.20 RLN92576.1 - 4.8e-32 110.9 0.0 6.2e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family Jacalin PF01419.17 RLN92578.1 - 0.0011 18.9 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 Jacalin-like lectin domain adh_short_C2 PF13561.6 RLN92579.1 - 2.5e-45 154.9 0.0 4.8e-45 153.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RLN92579.1 - 1e-19 70.8 0.0 2.5e-19 69.5 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Enoyl_reductase PF12241.8 RLN92579.1 - 0.0012 18.3 0.0 0.22 10.9 0.0 2.2 1 1 0 2 2 2 2 Trans-2-enoyl-CoA reductase catalytic region AdoHcyase_NAD PF00670.21 RLN92579.1 - 0.073 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Gly_transf_sug PF04488.15 RLN92580.1 - 1.7e-11 44.6 0.0 2.9e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 RLN92580.1 - 0.0019 17.7 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein COG7 PF10191.9 RLN92581.1 - 6.6e-59 199.9 0.0 2.3e-49 168.4 0.0 2.2 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) ATG16 PF08614.11 RLN92581.1 - 2.1 8.5 11.6 2.2 8.4 3.7 2.9 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Pkinase PF00069.25 RLN92582.1 - 1.9e-32 112.7 0.0 3.4e-32 111.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92582.1 - 1.9e-13 50.3 0.0 2.4e-12 46.7 0.0 2.3 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN92582.1 - 4.1e-05 23.0 0.0 0.00019 20.9 0.0 1.9 1 1 0 1 1 1 1 Kinase-like LRR_6 PF13516.6 RLN92584.1 - 0.008 16.2 1.3 0.029 14.4 0.1 2.6 3 0 0 3 3 3 1 Leucine Rich repeat Pkinase PF00069.25 RLN92585.1 - 8.4e-49 166.3 0.0 1.2e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92585.1 - 1.3e-45 155.7 0.0 1.8e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PTP_tm PF18861.1 RLN92585.1 - 0.033 14.2 0.9 0.063 13.3 0.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Haspin_kinase PF12330.8 RLN92585.1 - 0.091 11.7 0.1 0.27 10.1 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain MiAMP1 PF09117.10 RLN92585.1 - 0.24 11.7 4.3 6.9 7.0 0.8 3.2 2 1 0 2 2 2 0 MiAMP1 Adeno_E3_CR2 PF02439.15 RLN92585.1 - 0.29 10.9 1.1 0.56 10.0 1.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pkinase_Tyr PF07714.17 RLN92588.1 - 2.9e-57 193.9 0.0 9.2e-43 146.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Ank_4 PF13637.6 RLN92588.1 - 3.7e-54 180.4 5.6 1.3e-09 38.4 0.0 6.1 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN92588.1 - 6.3e-49 164.5 4.0 2.8e-17 63.1 0.2 4.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Pkinase PF00069.25 RLN92588.1 - 7.5e-49 166.5 0.0 1.2e-37 129.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ank_5 PF13857.6 RLN92588.1 - 6e-30 102.9 10.7 4.3e-07 30.1 0.1 7.5 2 1 6 8 8 7 7 Ankyrin repeats (many copies) Ank PF00023.30 RLN92588.1 - 1.3e-29 101.3 8.0 0.00024 21.4 0.0 7.7 7 0 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.6 RLN92588.1 - 1.5e-25 86.4 3.9 0.08 13.5 0.0 9.0 9 0 0 9 9 8 7 Ankyrin repeat NAGidase PF07555.13 RLN92588.1 - 0.0066 15.8 0.1 0.019 14.3 0.0 1.7 2 0 0 2 2 2 1 beta-N-acetylglucosaminidase Kinase-like PF14531.6 RLN92588.1 - 0.026 13.9 0.0 3.8 6.7 0.0 2.5 2 0 0 2 2 2 0 Kinase-like DUF3645 PF12359.8 RLN92588.1 - 0.043 13.2 0.2 15 5.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3645) UL40 PF10682.9 RLN92588.1 - 0.049 13.3 0.0 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein of human cytomegalovirus HHV-5 EF_TS PF00889.19 RLN92590.1 - 4.3e-54 183.3 0.8 6.5e-54 182.7 0.8 1.3 1 0 0 1 1 1 1 Elongation factor TS Spermine_synth PF01564.17 RLN92591.1 - 7.1e-41 139.7 0.0 1.2e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 RLN92591.1 - 7.4e-10 38.6 0.1 1.4e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 RLN92591.1 - 0.0013 19.4 0.0 0.0044 17.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_30 PF05430.11 RLN92591.1 - 0.032 14.1 0.0 0.069 13.0 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.12 RLN92591.1 - 0.071 13.8 0.0 0.63 10.7 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain TPR_12 PF13424.6 RLN92595.1 - 2.6e-07 30.8 6.1 0.1 12.9 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN92595.1 - 0.00021 21.2 2.2 0.55 10.6 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN92595.1 - 0.0021 18.1 9.6 0.048 13.8 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN92595.1 - 0.0035 17.3 5.7 0.75 10.0 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF688 PF05097.12 RLN92595.1 - 0.05 12.8 0.1 0.058 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) TPR_10 PF13374.6 RLN92595.1 - 0.059 13.3 13.1 0.84 9.6 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3301 PF11743.8 RLN92595.1 - 0.07 12.8 2.1 0.16 11.6 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) NOA36 PF06524.12 RLN92595.1 - 7.9 5.7 7.7 15 4.8 7.7 1.4 1 0 0 1 1 1 0 NOA36 protein TPR_16 PF13432.6 RLN92595.1 - 9.2 7.0 9.0 8 7.2 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN92596.1 - 3.7e-05 23.9 6.5 0.06 13.6 3.0 4.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN92596.1 - 0.016 15.2 3.5 0.24 11.5 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 RLN92596.1 - 0.03 14.5 6.5 0.068 13.4 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 RLN92596.1 - 0.049 14.3 1.9 33 5.5 0.5 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN92596.1 - 0.062 13.1 7.0 0.071 13.0 0.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN92596.1 - 0.12 12.5 6.2 0.16 12.1 0.6 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN92596.1 - 0.52 11.3 3.3 26 6.0 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat CBS PF00571.28 RLN92598.1 - 1.7e-06 28.4 0.0 2.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 CBS domain UEV PF05743.13 RLN92599.1 - 2.5e-29 101.6 0.2 4.9e-29 100.6 0.2 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 RLN92599.1 - 4.8e-19 68.1 0.4 1.7e-18 66.3 0.4 2.0 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 RLN92599.1 - 4.9e-05 23.0 0.3 0.00015 21.4 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Stork_head PF10264.9 RLN92599.1 - 0.051 13.7 0.2 0.33 11.2 0.0 2.5 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain FlaC_arch PF05377.11 RLN92599.1 - 7.8 7.0 5.8 8.1 6.9 1.3 3.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) LRR_8 PF13855.6 RLN92600.1 - 2.8e-33 113.4 66.1 3.1e-11 42.8 1.0 6.2 1 1 7 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 RLN92600.1 - 7e-31 105.8 29.3 1.5e-05 25.3 0.2 7.9 3 1 6 9 9 9 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN92600.1 - 2.5e-08 33.3 22.6 31 5.7 0.1 10.9 11 0 0 11 11 11 0 Leucine Rich Repeat LRR_6 PF13516.6 RLN92600.1 - 1.1e-07 31.3 15.6 0.1 12.7 0.0 7.8 8 0 0 8 8 8 3 Leucine Rich repeat LRR_9 PF14580.6 RLN92600.1 - 8.5e-07 28.6 14.6 0.0042 16.6 4.4 3.0 1 1 2 3 3 3 2 Leucine-rich repeat RsmF_methylt_CI PF17126.5 RLN92600.1 - 0.00011 22.2 2.7 2.4 8.3 0.1 5.0 4 1 0 5 5 5 2 RsmF rRNA methyltransferase first C-terminal domain LRR_3 PF07725.12 RLN92600.1 - 0.4 10.6 9.4 3 7.8 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat CSTF_C PF14304.6 RLN92600.1 - 0.93 9.1 10.2 6.6 6.4 0.9 4.2 5 0 0 5 5 5 0 Transcription termination and cleavage factor C-terminal CheY-binding PF09078.11 RLN92600.1 - 2.7 8.2 4.2 22 5.3 0.1 3.1 2 1 2 4 4 4 0 CheY binding TPR_2 PF07719.17 RLN92602.1 - 2.8e-15 55.1 0.0 0.00079 19.4 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN92602.1 - 1.6e-14 53.0 0.0 0.00019 21.1 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN92602.1 - 2.3e-13 49.2 0.0 0.00046 20.2 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN92602.1 - 3.7e-13 48.9 0.0 1.1e-06 28.2 0.0 2.6 2 0 0 2 2 2 2 TPR repeat FYVE PF01363.21 RLN92602.1 - 4.5e-13 49.1 9.3 7.5e-13 48.4 9.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger TPR_16 PF13432.6 RLN92602.1 - 1.3e-11 45.0 5.1 2.5e-06 28.0 0.6 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN92602.1 - 6.2e-09 36.2 0.5 9.2e-07 29.3 0.1 3.3 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN92602.1 - 1e-08 35.2 4.4 0.059 14.2 0.0 5.5 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 RLN92602.1 - 1e-08 35.3 0.2 1.3e-05 25.3 0.8 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN92602.1 - 3.7e-08 32.8 0.6 0.0068 16.4 0.0 4.2 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 RLN92602.1 - 1.9e-05 25.0 0.0 0.74 10.6 0.0 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 RLN92602.1 - 0.00054 19.7 1.0 0.0014 18.4 0.3 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 RLN92602.1 - 0.001 18.9 0.9 5.6 7.0 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN92602.1 - 0.0013 18.9 0.4 0.019 15.1 0.3 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN92602.1 - 0.0014 18.9 0.0 0.32 11.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN92602.1 - 0.012 15.8 0.1 0.18 12.1 0.0 2.4 2 1 1 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Ank_2 PF12796.7 RLN92602.1 - 0.054 14.1 0.0 7 7.3 0.0 2.4 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN92602.1 - 0.069 13.5 0.1 2.1 8.8 0.0 2.6 1 1 1 2 2 2 0 Ankyrin repeats (many copies) OrfB_Zn_ribbon PF07282.11 RLN92602.1 - 0.11 12.5 1.3 0.3 11.0 1.3 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain SDA1 PF05285.12 RLN92602.1 - 2.5 7.4 11.4 4.8 6.5 11.4 1.4 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 RLN92602.1 - 4.3 6.9 10.5 8.2 5.9 10.5 1.4 1 0 0 1 1 1 0 PPP4R2 Macro PF01661.21 RLN92605.1 - 3.8e-25 88.2 0.1 6.1e-25 87.6 0.1 1.3 1 0 0 1 1 1 1 Macro domain CRAL_TRIO_2 PF13716.6 RLN92605.1 - 3.5e-06 27.2 0.0 5.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Caldesmon PF02029.15 RLN92605.1 - 0.63 8.7 4.9 0.86 8.3 4.9 1.1 1 0 0 1 1 1 0 Caldesmon Flavi_NS2B PF01002.19 RLN92606.1 - 0.0014 18.5 0.1 0.0023 17.8 0.1 1.3 1 0 0 1 1 1 1 Flavivirus non-structural protein NS2B bZIP_2 PF07716.15 RLN92607.1 - 0.13 12.3 17.4 0.059 13.5 9.7 2.3 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 RLN92607.1 - 0.22 11.7 12.9 0.96 9.6 12.9 2.0 1 1 0 1 1 1 0 bZIP transcription factor Acyl-CoA_dh_1 PF00441.24 RLN92608.1 - 4.5e-50 169.8 2.8 7.6e-50 169.0 2.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RLN92608.1 - 8.3e-26 90.9 0.1 2.5e-25 89.3 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 RLN92608.1 - 8.9e-26 89.9 0.2 1.8e-25 89.0 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RLN92608.1 - 3.6e-20 72.6 0.7 5.7e-20 71.9 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 RLN92608.1 - 0.00022 21.0 0.5 0.0011 18.7 0.5 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal tRNA_edit PF04073.15 RLN92609.1 - 5.2e-22 78.2 0.5 1.3e-21 77.0 0.5 1.7 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain ProRS-C_1 PF09180.11 RLN92609.1 - 5.1e-21 74.7 1.4 1.2e-20 73.5 1.4 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 RLN92609.1 - 1.3e-18 67.6 0.0 2.7e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 RLN92609.1 - 3.7e-16 59.0 0.1 9.8e-16 57.7 0.1 1.8 1 0 0 1 1 1 1 Anticodon binding domain WD40 PF00400.32 RLN92610.1 - 2.7e-11 43.8 20.3 7.1e-05 23.5 0.3 9.6 11 0 0 11 11 11 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 RLN92610.1 - 0.0063 15.3 0.0 0.33 9.6 0.0 2.9 3 0 0 3 3 3 1 Nup133 N terminal like ANAPC4_WD40 PF12894.7 RLN92610.1 - 0.096 13.0 0.0 3.4 8.0 0.1 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DNA_pol_phi PF04931.13 RLN92610.1 - 4.3 5.3 5.3 7.9 4.4 5.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi Kazal_2 PF07648.15 RLN92611.1 - 9.2e-05 22.5 0.5 0.00017 21.6 0.5 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 RLN92611.1 - 0.00015 21.7 0.5 0.00023 21.1 0.5 1.3 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain DUF5039 PF16442.5 RLN92611.1 - 0.023 14.2 0.5 0.041 13.4 0.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5039) Kazal_1 PF00050.21 RLN92612.1 - 1.8e-07 31.0 0.3 3.3e-07 30.2 0.3 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 RLN92612.1 - 1.8e-05 24.8 0.2 3.1e-05 24.0 0.2 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain PDZ_6 PF17820.1 RLN92613.1 - 0.018 14.9 0.0 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 RLN92613.1 - 0.098 13.0 0.0 0.3 11.5 0.0 1.8 1 0 0 1 1 1 0 PDZ domain DUF2201_N PF13203.6 RLN92614.1 - 0.0076 15.9 5.3 0.53 9.8 0.4 2.4 2 0 0 2 2 2 2 Putative metallopeptidase domain PDZ_6 PF17820.1 RLN92614.1 - 0.016 15.0 0.0 0.048 13.5 0.0 1.9 1 0 0 1 1 1 0 PDZ domain DUF5082 PF16888.5 RLN92614.1 - 0.099 12.9 4.1 0.43 10.9 0.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF3289 PF11692.8 RLN92614.1 - 0.19 11.3 0.1 0.36 10.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3289) DIT1_PvcA PF05141.12 RLN92614.1 - 1.3 8.4 4.0 0.46 9.9 1.2 1.5 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein 5_nucleotid PF05761.14 RLN92615.1 - 7.8e-19 67.9 0.2 8e-19 67.9 0.2 1.0 1 0 0 1 1 1 1 5' nucleotidase family UTP25 PF06862.12 RLN92617.1 - 3.5e-144 481.1 0.5 5.1e-144 480.6 0.5 1.2 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CLTH PF10607.9 RLN92619.1 - 0.00011 22.1 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Pox_Ag35 PF03286.14 RLN92619.1 - 0.32 10.8 5.1 1.1 9.0 1.6 2.4 2 1 0 2 2 2 0 Pox virus Ag35 surface protein Herpes_LP PF03363.13 RLN92622.1 - 0.017 14.9 0.3 0.02 14.7 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus leader protein SET PF00856.28 RLN92623.1 - 2e-11 44.6 0.1 2e-10 41.3 0.1 2.0 1 1 0 1 1 1 1 SET domain MULE PF10551.9 RLN92624.1 - 1.2e-09 38.4 0.1 2.5e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain C2 PF00168.30 RLN92625.1 - 3.3e-11 43.4 0.1 9.4e-10 38.7 0.1 2.8 1 1 0 1 1 1 1 C2 domain Ins134_P3_kin PF05770.11 RLN92626.1 - 1.3e-11 44.4 0.0 1.4e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain TTL PF03133.15 RLN92626.1 - 0.015 14.4 0.0 0.017 14.3 0.0 1.0 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family ATP-grasp_3 PF02655.14 RLN92626.1 - 0.077 13.0 0.0 0.088 12.8 0.0 1.1 1 0 0 1 1 1 0 ATP-grasp domain Arm PF00514.23 RLN92627.1 - 8.3e-40 133.6 18.2 0.0011 18.9 0.0 12.1 12 0 0 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN92627.1 - 1.1e-07 32.1 24.4 0.3 11.6 1.3 8.4 5 3 4 9 9 9 5 HEAT-like repeat Atx10homo_assoc PF09759.9 RLN92627.1 - 0.0014 18.6 0.0 7.1 6.7 0.0 4.3 4 2 1 5 5 5 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 RLN92627.1 - 0.0071 16.5 18.1 62 4.2 0.0 9.5 11 0 0 11 11 11 0 HEAT repeat DUF294_C PF10335.9 RLN92627.1 - 0.06 13.1 2.3 0.79 9.5 0.1 4.0 4 1 2 6 6 6 0 Putative nucleotidyltransferase substrate binding domain Tex_N PF09371.10 RLN92627.1 - 0.41 10.3 5.1 55 3.4 0.4 5.0 2 1 1 4 4 4 0 Tex-like protein N-terminal domain HEAT_2 PF13646.6 RLN92627.1 - 5.7 7.4 38.9 0.16 12.4 0.5 6.8 5 2 5 10 10 10 0 HEAT repeats DHquinase_II PF01220.19 RLN92628.1 - 2.3e-07 30.6 0.0 6.6e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 Dehydroquinase class II zf-C2H2_4 PF13894.6 RLN92628.1 - 0.041 14.7 1.7 0.1 13.5 1.7 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger CCT PF06203.14 RLN92629.1 - 4.5e-15 55.4 8.0 8.5e-15 54.5 8.0 1.5 1 0 0 1 1 1 1 CCT motif UL21a PF17636.2 RLN92629.1 - 0.025 14.6 0.7 0.058 13.4 0.7 1.7 1 0 0 1 1 1 0 Viral Unique Long protein 21a Gcd10p PF04189.13 RLN92634.1 - 9.8e-57 192.3 0.0 1.5e-56 191.7 0.0 1.3 1 0 0 1 1 1 1 Gcd10p family BsuPI PF12690.7 RLN92634.1 - 0.0033 17.4 0.0 0.015 15.3 0.0 1.9 2 0 0 2 2 2 1 Intracellular proteinase inhibitor CbiA PF01656.23 RLN92635.1 - 8.8e-19 67.8 0.0 1.2e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 RLN92635.1 - 9.6e-19 68.0 0.0 1.9e-18 67.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain ParA PF10609.9 RLN92635.1 - 2e-14 53.7 0.1 6.6e-14 51.9 0.1 1.8 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 RLN92635.1 - 1.1e-10 41.2 0.0 1.7e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 RLN92635.1 - 5.1e-10 39.2 0.2 6e-09 35.7 0.2 2.4 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 RLN92635.1 - 8.8e-07 28.4 0.0 1.3e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_24 PF13479.6 RLN92635.1 - 0.0024 17.6 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 RLN92635.1 - 0.0026 17.6 1.0 13 5.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain Fer4_NifH PF00142.18 RLN92635.1 - 0.065 12.7 1.0 1.6 8.1 0.7 2.3 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 RLN92635.1 - 0.08 12.6 0.7 0.58 9.8 0.3 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 RLN92635.1 - 0.17 11.4 1.7 0.17 11.4 0.6 1.5 2 0 0 2 2 2 0 AAA domain Metallophos PF00149.28 RLN92637.1 - 6.3e-17 62.7 0.2 1.2e-16 61.8 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 RLN92637.1 - 3.9e-16 59.7 0.0 8.1e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 RLN92637.1 - 1.9e-15 57.2 0.0 3.9e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Arteri_env PF01606.16 RLN92637.1 - 0.16 11.8 0.0 0.44 10.4 0.0 1.6 2 0 0 2 2 2 0 Arterivirus envelope protein Peptidase_M13_N PF05649.13 RLN92638.1 - 1.7e-23 84.0 0.1 2e-23 83.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M13 PYRIN PF02758.16 RLN92641.1 - 0.041 14.0 0.3 17 5.6 0.0 4.1 4 0 0 4 4 4 0 PAAD/DAPIN/Pyrin domain FBP_C PF16571.5 RLN92641.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger Helicase_C PF00271.31 RLN92641.1 - 0.19 12.1 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Med30 PF11315.8 RLN92642.1 - 0.00098 19.3 9.4 0.00098 19.3 9.4 2.9 1 1 2 3 3 3 1 Mediator complex subunit 30 E7 PF00527.18 RLN92642.1 - 0.08 13.1 2.5 0.42 10.8 2.5 2.3 1 0 0 1 1 1 0 E7 protein, Early protein CODH_A_N PF18537.1 RLN92642.1 - 0.24 11.5 1.6 2 8.5 0.0 2.9 3 0 0 3 3 3 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain DUF948 PF06103.11 RLN92642.1 - 0.62 10.4 4.3 1 9.7 1.3 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) RPW8 PF05659.11 RLN92642.1 - 2.3 7.9 13.3 2.3 7.9 1.5 3.2 2 1 2 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Med9 PF07544.13 RLN92642.1 - 2.4 8.3 13.1 0.55 10.3 5.7 3.2 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DASH_Dad2 PF08654.10 RLN92642.1 - 3 8.3 18.7 2.9 8.4 8.1 3.5 2 1 0 3 3 3 0 DASH complex subunit Dad2 UPF0449 PF15136.6 RLN92642.1 - 6.2 7.3 19.7 0.37 11.3 5.2 3.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 Pkinase_Tyr PF07714.17 RLN92644.1 - 2.6e-34 118.7 0.0 1.3e-33 116.4 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RLN92644.1 - 5e-32 111.3 0.0 2e-30 106.0 0.0 2.8 2 2 1 3 3 3 1 Protein kinase domain APH PF01636.23 RLN92644.1 - 0.0073 16.3 0.9 0.088 12.7 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 RLN92644.1 - 0.02 14.5 0.2 0.067 12.8 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Spec3 PF15795.5 RLN92644.1 - 0.22 12.1 0.1 0.46 11.1 0.1 1.5 1 0 0 1 1 1 0 Ectodermal ciliogenesis protein Pkinase_Tyr PF07714.17 RLN92645.1 - 4.2e-45 154.0 0.0 1.3e-44 152.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN92645.1 - 2.8e-41 141.6 0.0 4.2e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain GWT1 PF06423.12 RLN92645.1 - 0.026 14.7 2.7 0.054 13.6 2.7 1.6 1 0 0 1 1 1 0 GWT1 LRR_6 PF13516.6 RLN92646.1 - 2.9e-06 26.9 2.1 0.074 13.1 1.5 3.4 3 0 0 3 3 3 3 Leucine Rich repeat MORN PF02493.20 RLN92650.1 - 6.7e-76 245.9 112.1 8.5e-07 28.5 1.0 24.0 23 1 0 23 23 23 19 MORN repeat RabGAP-TBC PF00566.18 RLN92650.1 - 2.1e-36 125.6 0.2 3.1e-36 125.1 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain fn3 PF00041.21 RLN92650.1 - 2.7e-17 62.9 1.8 1.5e-10 41.3 0.1 3.0 3 0 0 3 3 3 2 Fibronectin type III domain Avl9 PF09794.9 RLN92650.1 - 7.6e-10 38.0 0.0 4.7e-06 25.5 0.0 2.3 1 1 1 2 2 2 2 Transport protein Avl9 PDZ PF00595.24 RLN92650.1 - 5.5e-05 23.4 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Pur_ac_phosph_N PF16656.5 RLN92650.1 - 0.00052 20.5 9.2 0.089 13.4 0.1 3.2 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Rhodanese PF00581.20 RLN92650.1 - 0.0088 16.5 0.0 4.4 7.9 0.0 2.7 2 0 0 2 2 2 1 Rhodanese-like domain PDZ_6 PF17820.1 RLN92650.1 - 0.0088 15.9 0.2 0.024 14.5 0.2 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RLN92650.1 - 0.021 15.1 0.1 0.055 13.8 0.1 1.7 1 0 0 1 1 1 0 PDZ domain PhoD_N PF16655.5 RLN92650.1 - 0.08 13.5 0.0 18 5.9 0.0 3.1 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain PH PF00169.29 RLN92657.1 - 4e-05 24.1 0.0 8.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 PH domain RGS12_usC PF16612.5 RLN92657.1 - 0.019 15.4 0.1 0.07 13.6 0.0 1.9 2 0 0 2 2 2 0 C-terminal unstructured region of RGS12 PH_6 PF15406.6 RLN92657.1 - 0.087 13.1 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Beach PF02138.18 RLN92658.1 - 7e-116 386.4 0.0 9.7e-116 386.0 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 RLN92658.1 - 6.2e-14 52.2 12.5 0.0023 18.7 0.1 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat PH_BEACH PF14844.6 RLN92658.1 - 1.1e-11 44.7 0.0 1.4e-10 41.1 0.0 2.5 1 1 0 1 1 1 1 PH domain associated with Beige/BEACH ANAPC4_WD40 PF12894.7 RLN92658.1 - 7.9e-06 26.1 0.2 0.049 13.9 0.0 4.2 2 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN92658.1 - 0.0018 17.3 1.8 6.6 5.6 0.1 3.4 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein GRAM PF02893.20 RLN92658.1 - 0.028 14.3 0.0 0.072 13.0 0.0 1.7 1 0 0 1 1 1 0 GRAM domain PQQ PF01011.21 RLN92658.1 - 0.077 13.0 1.7 0.65 10.0 0.0 3.1 3 0 0 3 3 3 0 PQQ enzyme repeat PQQ_3 PF13570.6 RLN92658.1 - 0.13 12.8 5.3 1.4 9.5 0.0 4.7 4 1 1 5 5 5 0 PQQ-like domain HCV_NS5a_C PF12941.7 RLN92659.1 - 1.2 9.0 6.3 0.12 12.2 1.2 1.9 2 0 0 2 2 2 0 HCV NS5a protein C-terminal region GTP_EFTU PF00009.27 RLN92660.1 - 7.2e-45 152.9 0.0 9.9e-45 152.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 RLN92660.1 - 2.1e-35 121.9 3.4 4.1e-35 121.0 3.4 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 RLN92660.1 - 4.6e-22 78.1 0.0 8.7e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 RLN92660.1 - 1.1e-06 29.0 0.0 2.2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 RLN92660.1 - 5e-06 26.5 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Septin PF00735.18 RLN92660.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Septin His_biosynth PF00977.21 RLN92661.1 - 1.1e-41 142.9 0.4 7.9e-41 140.0 0.4 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 RLN92661.1 - 0.0044 16.1 0.0 0.011 14.9 0.1 1.6 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Serine_rich PF08824.10 RLN92662.1 - 0.01 15.8 7.4 0.01 15.8 7.4 3.8 2 1 2 4 4 4 0 Serine rich protein interaction domain betaPIX_CC PF16523.5 RLN92662.1 - 0.36 10.7 6.7 0.43 10.4 0.8 3.6 3 1 0 3 3 3 0 betaPIX coiled coil Spc7 PF08317.11 RLN92662.1 - 7.6 5.3 32.6 1.8 7.4 12.3 3.4 2 2 1 3 3 3 0 Spc7 kinetochore protein MatE PF01554.18 RLN92663.1 - 2.9e-59 199.3 22.0 5.2e-30 104.2 1.8 3.1 3 0 0 3 3 3 2 MatE MurJ PF03023.14 RLN92663.1 - 2.5e-07 29.7 14.0 3.8e-07 29.1 14.0 1.2 1 0 0 1 1 1 1 Lipid II flippase MurJ LmjF365940-deam PF14421.6 RLN92664.1 - 0.018 14.7 0.0 0.043 13.4 0.0 1.6 2 0 0 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases EF-hand_7 PF13499.6 RLN92666.1 - 2.5e-10 40.7 0.1 2.7e-05 24.5 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN92666.1 - 6.1e-10 37.9 0.0 0.0063 16.0 0.2 3.5 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 RLN92666.1 - 7.8e-08 31.5 0.3 0.084 12.4 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 RLN92666.1 - 2.7e-07 30.0 0.1 0.48 10.5 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain WD40 PF00400.32 RLN92666.1 - 1.8e-05 25.4 11.0 5.8 8.0 0.0 7.1 8 0 0 8 8 8 2 WD domain, G-beta repeat EF-hand_8 PF13833.6 RLN92666.1 - 0.0016 18.2 1.6 2.3 8.2 0.5 3.7 2 1 1 3 3 3 1 EF-hand domain pair SLATT_2 PF18183.1 RLN92666.1 - 0.035 13.9 0.0 0.098 12.4 0.0 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 2 DUF1156 PF06634.12 RLN92666.1 - 0.11 12.6 2.0 0.13 12.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1156) FumaraseC_C PF10415.9 RLN92667.1 - 1.8e-07 31.4 0.0 3.3e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Fumarase C C-terminus Integrase_Zn PF02022.19 RLN92669.1 - 0.35 10.9 8.2 11 6.0 0.4 4.0 3 1 1 4 4 4 0 Integrase Zinc binding domain Xpo1 PF08389.12 RLN92670.1 - 1.9e-05 24.8 0.1 9.4e-05 22.5 0.1 2.3 1 0 0 1 1 1 1 Exportin 1-like protein NAD_binding_6 PF08030.12 RLN92671.1 - 8.8e-27 94.1 0.1 1.1e-26 93.9 0.1 1.1 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Cytochrome_B PF00033.19 RLN92672.1 - 7e-73 244.5 17.6 7e-73 244.5 17.6 1.8 2 1 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 RLN92672.1 - 8.7e-42 143.0 12.6 8.7e-42 143.0 12.6 1.9 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 RLN92672.1 - 2.8e-36 123.9 4.2 2.8e-36 123.9 4.2 3.4 3 1 0 3 3 3 1 Cytochrome b(C-terminal)/b6/petD COX2 PF00116.20 RLN92673.1 - 6.1e-60 200.4 0.9 6.7e-60 200.3 0.1 1.4 2 0 0 2 2 2 1 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.15 RLN92673.1 - 4.1e-31 107.0 4.0 7.3e-31 106.2 4.0 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain Complex1_30kDa PF00329.19 RLN92674.1 - 3.6e-41 140.6 0.0 5e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit LON_substr_bdg PF02190.16 RLN92675.1 - 1.6e-07 31.5 1.0 8e-05 22.6 0.0 2.7 2 1 0 2 2 2 2 ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 PF03226.14 RLN92675.1 - 0.0003 20.9 0.0 0.00049 20.3 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF5039 PF16442.5 RLN92675.1 - 0.082 12.4 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) NDK PF00334.19 RLN92676.1 - 6.9e-52 175.0 0.0 9.5e-52 174.6 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PsbQ PF05757.11 RLN92676.1 - 1.3 8.8 5.9 1.8 8.2 5.9 1.3 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) DUF3452 PF11934.8 RLN92677.1 - 0.069 12.7 0.1 0.092 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Nop53 PF07767.11 RLN92677.1 - 5.5 6.3 29.3 6.9 5.9 29.3 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 RLN92677.1 - 6.7 4.9 16.9 7.6 4.7 16.9 1.0 1 0 0 1 1 1 0 CDC45-like protein cNMP_binding PF00027.29 RLN92678.1 - 1.2e-21 76.6 0.0 2.3e-14 53.2 0.0 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RGS PF00615.19 RLN92678.1 - 4.6e-20 72.1 0.3 8.8e-20 71.1 0.3 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain PP2C PF00481.21 RLN92680.1 - 3e-66 223.7 0.0 3.7e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Mrr_cat PF04471.12 RLN92680.1 - 6.4e-11 42.3 0.0 1.7e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Restriction endonuclease DUF2034 PF10356.9 RLN92680.1 - 1.1e-08 34.8 0.0 0.00041 19.8 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) PP2C_2 PF13672.6 RLN92680.1 - 5.9e-07 29.3 0.7 0.00014 21.6 0.1 2.5 2 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 RLN92680.1 - 0.0042 17.0 0.1 1.4 8.8 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Peptidase_C92 PF05708.12 RLN92681.1 - 0.0012 19.0 0.0 0.0015 18.7 0.0 1.2 1 0 0 1 1 1 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family DUF4224 PF13986.6 RLN92681.1 - 0.12 12.3 0.0 0.61 10.0 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4224) cwf21 PF08312.12 RLN92682.1 - 2.8e-07 30.6 10.4 2.8e-07 30.6 10.4 2.9 2 0 0 2 2 2 1 cwf21 domain Peptidase_C48 PF02902.19 RLN92683.1 - 2.7e-14 53.5 0.0 4.4e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4746 PF15928.5 RLN92683.1 - 0.037 13.5 2.1 0.062 12.7 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nudix_hydro PF18290.1 RLN92683.1 - 0.046 13.7 0.2 1.6 8.8 0.1 2.6 2 0 0 2 2 2 0 Nudix hydrolase domain Peptidase_C57 PF03290.13 RLN92683.1 - 0.065 12.0 0.3 0.17 10.5 0.0 1.7 2 0 0 2 2 2 0 Vaccinia virus I7 processing peptidase XPG_I PF00867.18 RLN92684.1 - 7.9e-17 61.4 0.0 1.6e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 RLN92684.1 - 3.6e-07 30.6 0.0 8.3e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 RLN92684.1 - 0.00096 18.7 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing ADH_zinc_N_2 PF13602.6 RLN92684.1 - 0.038 15.0 0.1 0.14 13.2 0.0 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DUF3413 PF11893.8 RLN92684.1 - 0.073 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) TMP-TENI PF02581.17 RLN92686.1 - 5e-26 91.1 4.8 6e-26 90.9 4.8 1.1 1 0 0 1 1 1 1 Thiamine monophosphate synthase ThiG PF05690.14 RLN92686.1 - 7.6e-06 25.4 0.3 7.6e-06 25.4 0.3 1.6 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 RLN92686.1 - 0.00014 21.4 0.5 0.26 10.7 0.3 2.3 1 1 1 2 2 2 2 Histidine biosynthesis protein NMO PF03060.15 RLN92686.1 - 0.00019 21.0 4.4 0.0012 18.3 4.4 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 RLN92686.1 - 0.0025 17.1 0.6 0.08 12.1 0.2 2.1 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase OMPdecase PF00215.24 RLN92686.1 - 0.068 12.7 0.8 0.086 12.4 0.8 1.5 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Anillin_N PF16018.5 RLN92687.1 - 0.1 13.2 0.3 0.1 13.2 0.3 2.1 2 1 1 3 3 3 0 Anillin N-terminus Nha1_C PF08619.10 RLN92687.1 - 0.64 9.2 8.0 0.67 9.1 8.0 1.3 1 1 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Cpn60_TCP1 PF00118.24 RLN92688.1 - 2.9e-97 326.4 0.1 3.2e-97 326.2 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TraH_2 PF06871.11 RLN92688.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 TraH_2 Anoctamin PF04547.12 RLN92690.1 - 1.8e-50 172.1 0.1 7.9e-50 170.0 0.0 2.1 2 0 0 2 2 2 1 Calcium-activated chloride channel AA_permease_2 PF13520.6 RLN92690.1 - 0.015 14.1 0.0 0.015 14.1 0.0 2.5 3 0 0 3 3 3 0 Amino acid permease Ninjurin PF04923.12 RLN92690.1 - 0.26 11.2 1.8 1.3 9.0 1.8 2.2 1 0 0 1 1 1 0 Ninjurin DUF2976 PF11190.8 RLN92690.1 - 0.48 10.3 5.0 1.9 8.3 5.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) DUF2304 PF10066.9 RLN92690.1 - 2.4 8.4 9.2 3.8 7.8 4.0 3.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) HlyIII PF03006.20 RLN92692.1 - 3.8e-58 196.8 28.8 2.9e-52 177.6 22.9 2.1 2 0 0 2 2 2 2 Haemolysin-III related DUF962 PF06127.11 RLN92692.1 - 0.43 10.7 0.0 0.43 10.7 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF962) DUF1035 PF06281.12 RLN92693.1 - 0.2 11.7 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) ThiS PF02597.20 RLN92694.1 - 9.8e-13 48.5 0.0 1.2e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 ThiS family HSP70 PF00012.20 RLN92697.1 - 1.8e-221 736.5 4.6 2.2e-221 736.2 4.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN92697.1 - 1.6e-15 56.7 0.0 2.8e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 RLN92697.1 - 0.0022 17.8 0.0 0.0054 16.5 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDE_1 PF03184.19 RLN92697.1 - 0.0026 17.4 0.0 0.0054 16.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDR PF08841.10 RLN92697.1 - 0.015 14.3 0.3 0.099 11.6 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 RLN92697.1 - 0.041 13.2 0.1 0.095 12.0 0.1 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase ABC2_membrane PF01061.24 RLN92698.1 - 9.6e-29 100.3 18.9 9.6e-29 100.3 18.9 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 RLN92698.1 - 8.8e-08 31.6 12.7 1.2e-07 31.2 12.7 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 RLN92698.1 - 0.013 14.8 6.7 0.018 14.3 6.7 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein CAP_GLY PF01302.25 RLN92699.1 - 5.1e-20 71.3 0.2 8.5e-20 70.5 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain DnaJ PF00226.31 RLN92699.1 - 2.2e-17 62.9 0.2 3.6e-17 62.2 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain ABC2_membrane PF01061.24 RLN92700.1 - 2.5e-27 95.7 18.0 2.5e-27 95.7 18.0 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 RLN92700.1 - 1.4e-07 30.9 12.3 1.8e-07 30.6 12.3 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 RLN92700.1 - 0.0071 15.7 8.3 0.0091 15.3 8.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF1336 PF07059.12 RLN92702.1 - 9.4e-49 166.5 0.0 1.6e-48 165.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) DUF4504 PF14953.6 RLN92702.1 - 1.5e-11 44.2 0.0 1.6e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4504) PH PF00169.29 RLN92702.1 - 9.6e-08 32.5 0.1 0.0035 17.8 0.0 2.5 2 0 0 2 2 2 2 PH domain PH_8 PF15409.6 RLN92702.1 - 0.0025 18.0 0.1 0.042 14.1 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 RLN92702.1 - 0.016 15.6 0.2 0.04 14.4 0.2 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Metallophos_2 PF12850.7 RLN92703.1 - 2.4e-05 24.6 0.2 0.0026 18.0 0.1 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Nuc_sug_transp PF04142.15 RLN92704.1 - 3.6e-80 269.5 19.4 4.2e-80 269.3 19.4 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 RLN92704.1 - 4.9e-07 29.2 16.1 7.3e-07 28.7 16.1 1.4 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 RLN92704.1 - 5e-05 22.4 0.6 5e-05 22.4 0.6 2.2 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like PUNUT PF16913.5 RLN92704.1 - 0.0016 17.7 15.6 0.003 16.9 8.8 2.3 1 1 0 2 2 2 2 Purine nucleobase transmembrane transport EamA PF00892.20 RLN92704.1 - 0.026 14.7 4.5 0.026 14.7 4.5 3.6 2 2 1 3 3 3 0 EamA-like transporter family Abhydrolase_6 PF12697.7 RLN92705.1 - 4.7e-17 63.3 4.0 6.3e-17 62.9 4.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN92705.1 - 1.7e-07 30.8 0.2 5e-07 29.2 0.2 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN92705.1 - 3.9e-06 26.7 0.0 1.9e-05 24.4 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 RLN92705.1 - 0.0048 16.8 0.2 0.009 15.9 0.2 1.4 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase2 PF12740.7 RLN92705.1 - 0.015 14.2 0.0 0.021 13.8 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 RLN92705.1 - 0.018 14.8 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 RLN92705.1 - 0.041 13.7 0.1 0.088 12.7 0.1 1.5 1 0 0 1 1 1 0 Serine hydrolase PGAP1 PF07819.13 RLN92705.1 - 0.044 13.5 0.0 0.096 12.4 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein Esterase PF00756.20 RLN92705.1 - 0.09 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 RLN92705.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain THOC2_N PF16134.5 RLN92706.1 - 3.2e-58 197.9 1.0 3e-54 184.7 1.0 3.1 1 1 0 1 1 1 1 THO complex subunit 2 N-terminus Thoc2 PF11732.8 RLN92706.1 - 4e-29 100.5 0.1 9.8e-29 99.2 0.1 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Tho2 PF11262.8 RLN92706.1 - 2.1e-06 27.2 0.5 2e-05 24.0 0.2 2.2 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 AOX PF01786.17 RLN92708.1 - 1.3e-91 306.0 0.0 1.7e-91 305.6 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 RLN92708.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 1 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 ABC2_membrane PF01061.24 RLN92709.1 - 2.9e-30 105.2 25.5 4e-30 104.8 25.5 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN92709.1 - 5e-25 88.6 0.0 7.2e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN92709.1 - 1.5e-11 44.7 0.3 6e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RLN92709.1 - 9.6e-06 25.2 0.0 0.014 14.8 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RLN92709.1 - 0.00056 20.3 0.0 0.00089 19.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 RLN92709.1 - 0.00077 19.2 0.1 0.0022 17.7 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 RLN92709.1 - 0.0017 18.9 0.0 0.0033 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 RLN92709.1 - 0.0075 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 RLN92709.1 - 0.015 14.8 0.1 0.033 13.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 RLN92709.1 - 0.016 14.9 0.0 3.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase AAA_23 PF13476.6 RLN92709.1 - 0.024 15.1 0.1 0.04 14.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RLN92709.1 - 0.025 14.5 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 RLN92709.1 - 0.025 14.5 0.0 3 7.7 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 RLN92709.1 - 0.027 14.2 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RLN92709.1 - 0.032 14.5 0.0 0.068 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RLN92709.1 - 0.13 12.0 0.0 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RLN92709.1 - 0.15 12.3 0.1 0.26 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RLN92709.1 - 0.17 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 RLN92709.1 - 0.17 12.1 0.0 0.67 10.2 0.0 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 RLN92709.1 - 0.2 12.1 0.0 2.1 8.8 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AOX PF01786.17 RLN92710.1 - 8.3e-97 323.0 2.7 2.6e-91 305.0 0.1 2.1 2 0 0 2 2 2 2 Alternative oxidase MAPEG PF01124.18 RLN92711.1 - 3.6e-15 56.0 0.9 5e-15 55.5 0.9 1.2 1 0 0 1 1 1 1 MAPEG family Herpes_LMP2 PF07415.11 RLN92712.1 - 0.047 12.5 0.4 0.078 11.7 0.4 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DICT PF10069.9 RLN92712.1 - 0.061 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Sensory domain in DIguanylate Cyclases and Two-component system DUF1297 PF06973.12 RLN92712.1 - 0.22 11.0 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) MAPEG PF01124.18 RLN92713.1 - 5.5e-16 58.6 0.6 6.8e-16 58.4 0.6 1.1 1 0 0 1 1 1 1 MAPEG family XdhC_C PF13478.6 RLN92713.1 - 0.071 13.6 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain MAPEG PF01124.18 RLN92714.1 - 1e-16 61.0 0.5 1.3e-16 60.7 0.5 1.1 1 0 0 1 1 1 1 MAPEG family HofP PF10748.9 RLN92714.1 - 0.08 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 DNA utilization proteins HofP YrbL-PhoP_reg PF10707.9 RLN92715.1 - 0.021 14.3 0.4 0.081 12.4 0.4 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Trnau1ap PF17654.1 RLN92715.1 - 0.17 12.7 1.5 1.4 9.8 0.1 3.1 3 0 0 3 3 3 0 Selenocysteine tRNA 1 associated proteins Myb_DNA-binding PF00249.31 RLN92715.1 - 1.1 9.5 4.9 46 4.3 0.0 4.3 4 0 0 4 4 4 0 Myb-like DNA-binding domain PhaC_N PF07167.13 RLN92715.1 - 1.5 8.4 6.5 0.16 11.6 0.2 2.6 4 0 0 4 4 4 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Adap_comp_sub PF00928.21 RLN92716.1 - 6.6e-21 74.9 0.0 9.3e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 RLN92716.1 - 0.0024 17.8 0.1 0.0044 17.0 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TniB PF05621.11 RLN92716.1 - 0.0093 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein Mon1 PF03164.14 RLN92716.1 - 0.069 12.2 0.0 0.094 11.8 0.0 1.1 1 0 0 1 1 1 0 Trafficking protein Mon1 Hist_deacetyl PF00850.19 RLN92718.1 - 9e-07 28.6 0.0 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain MIP PF00230.20 RLN92719.1 - 8.7e-90 300.4 10.2 2.7e-44 151.6 5.5 2.0 2 0 0 2 2 2 2 Major intrinsic protein Glyco_transf_28 PF03033.20 RLN92719.1 - 0.13 12.3 0.5 7.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain XK-related PF09815.9 RLN92719.1 - 0.26 10.3 6.6 1.4 7.9 0.6 2.3 2 0 0 2 2 2 0 XK-related protein DHC_N1 PF08385.12 RLN92720.1 - 1.4e-182 608.3 17.5 1.4e-182 608.3 17.5 2.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 RLN92720.1 - 1.2e-74 251.8 16.0 1.2e-74 251.8 16.0 3.6 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 DUF3583 PF12126.8 RLN92720.1 - 0.00024 20.7 1.1 0.0013 18.3 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3583) 5_3_exonuc PF01367.20 RLN92720.1 - 0.016 15.8 0.1 0.49 11.0 0.0 3.7 2 1 1 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold CagY_I PF14585.6 RLN92720.1 - 1.2 9.3 4.5 0.66 10.1 0.2 2.9 3 0 0 3 3 3 0 CagY type 1 repeat UTP15_C PF09384.10 RLN92720.1 - 2.7 7.7 7.2 2.3 7.9 0.1 3.9 4 0 0 4 4 4 0 UTP15 C terminal TipAS PF07739.13 RLN92720.1 - 8 7.0 9.7 6.5 7.3 0.1 5.0 5 0 0 5 5 5 0 TipAS antibiotic-recognition domain EMP24_GP25L PF01105.24 RLN92721.1 - 4.6e-07 29.9 0.7 4.6e-06 26.7 0.1 2.0 1 1 1 2 2 2 2 emp24/gp25L/p24 family/GOLD BPL_N PF09825.9 RLN92721.1 - 0.009 15.1 0.2 0.011 14.9 0.2 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal Cyclin_N PF00134.23 RLN92722.1 - 1.2e-07 31.6 4.0 3.5e-07 30.0 0.3 2.6 3 0 0 3 3 3 1 Cyclin, N-terminal domain Trypsin PF00089.26 RLN92722.1 - 2.4e-05 24.3 0.1 4.4e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Trypsin Q_salvage PF10343.9 RLN92723.1 - 5.8e-06 26.1 0.1 7.9e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Q_salvage PF10343.9 RLN92724.1 - 1.1e-52 179.4 0.0 1.2e-52 179.2 0.0 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family NIF PF03031.18 RLN92725.1 - 3.1e-33 114.7 1.1 1.1e-29 103.2 0.0 2.3 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase Defensin_2 PF01097.18 RLN92725.1 - 0.093 12.7 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Arthropod defensin Helitron_like_N PF14214.6 RLN92727.1 - 1.8e-21 77.2 0.0 1.8e-21 77.2 0.0 2.7 4 0 0 4 4 4 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 RLN92727.1 - 6e-20 71.7 0.9 5.8e-19 68.5 0.1 2.4 2 1 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.6 RLN92727.1 - 1.1e-14 54.7 0.6 9e-14 51.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 RLN92727.1 - 1.9e-07 31.5 0.0 2e-06 28.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain Fibrillarin PF01269.17 RLN92727.1 - 0.033 13.3 0.0 11 5.0 0.0 3.2 3 0 0 3 3 3 0 Fibrillarin AAA_29 PF13555.6 RLN92727.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain CobA_CobO_BtuR PF02572.15 RLN92727.1 - 0.15 12.3 0.0 2.2 8.5 0.0 2.7 3 0 0 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Serpulina_VSP PF05540.11 RLN92728.1 - 0.24 10.4 0.0 0.26 10.3 0.0 1.1 1 0 0 1 1 1 0 Serpulina hyodysenteriae variable surface protein GST_N_2 PF13409.6 RLN92729.1 - 1.7e-08 34.7 0.0 4.1e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain UcrQ PF02939.16 RLN92729.1 - 2e-08 34.0 0.0 3.4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 UcrQ family GST_C_2 PF13410.6 RLN92729.1 - 2.8e-05 24.1 0.0 7.4e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RLN92729.1 - 0.00031 20.9 0.1 0.00057 20.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cyt_b-c1_8 PF10890.8 RLN92729.1 - 0.00067 20.0 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 GST_C_3 PF14497.6 RLN92729.1 - 0.0018 18.4 0.0 0.0036 17.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_2_N PF02837.18 RLN92729.1 - 0.12 12.3 0.0 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, sugar binding domain LIM PF00412.22 RLN92731.1 - 2.8e-05 24.3 12.5 8.1e-05 22.8 6.5 3.7 2 1 1 3 3 3 2 LIM domain Med25_SD1 PF11235.8 RLN92731.1 - 0.009 16.4 0.1 0.012 16.0 0.1 1.3 1 0 0 1 1 1 1 Mediator complex subunit 25 synapsin 1 PhnA_Zn_Ribbon PF08274.12 RLN92731.1 - 0.21 11.6 7.9 0.92 9.5 0.1 3.6 4 0 0 4 4 4 0 PhnA Zinc-Ribbon LLC1 PF14945.6 RLN92731.1 - 0.25 11.9 0.8 0.36 11.4 0.0 1.6 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein DA1-like PF12315.8 RLN92732.1 - 2.4e-22 79.4 1.3 1.1e-14 54.4 0.2 2.9 1 1 1 2 2 2 2 Protein DA1 HSP70 PF00012.20 RLN92733.1 - 1.2e-178 595.1 7.5 1.4e-178 594.9 7.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN92733.1 - 0.00022 20.2 1.7 0.00056 18.8 0.1 2.4 2 1 0 2 2 2 1 MreB/Mbl protein DUF4795 PF16043.5 RLN92733.1 - 0.0026 17.4 1.7 0.0026 17.4 1.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4795) FGGY_C PF02782.16 RLN92733.1 - 0.0055 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain RNA_pol_Rpb2_6 PF00562.28 RLN92733.1 - 0.02 14.0 1.1 0.029 13.4 1.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 DUF4192 PF13830.6 RLN92733.1 - 0.96 9.5 6.0 1.9 8.5 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) AAA_6 PF12774.7 RLN92734.1 - 7.8e-154 511.5 0.1 2.5e-153 509.8 0.0 1.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN92734.1 - 3.2e-134 448.0 10.6 3.2e-134 448.0 10.6 2.5 2 1 1 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_AAA_lid PF17852.1 RLN92734.1 - 7.7e-29 100.4 0.0 2.8e-28 98.6 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RLN92734.1 - 2.3e-11 43.8 0.0 0.00089 19.3 0.0 3.7 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RLN92734.1 - 0.0058 16.9 1.0 5.3 7.3 0.0 3.7 3 0 0 3 3 3 1 AAA domain DUF853 PF05872.12 RLN92734.1 - 0.007 15.0 1.5 0.99 7.9 0.1 2.2 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF853) AAA_18 PF13238.6 RLN92734.1 - 0.016 15.8 0.1 0.24 11.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 RLN92734.1 - 0.023 15.1 0.1 2.1 8.8 0.0 3.0 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 RLN92734.1 - 0.031 13.8 1.1 6.1 6.3 0.0 3.2 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_16 PF13191.6 RLN92734.1 - 0.044 14.2 0.9 2.2 8.6 0.0 3.6 3 0 0 3 3 3 0 AAA ATPase domain NFRKB_winged PF14465.6 RLN92734.1 - 0.048 13.9 5.6 0.12 12.6 0.2 3.7 3 0 0 3 3 2 0 NFRKB Winged Helix-like AAA PF00004.29 RLN92734.1 - 0.12 12.8 1.1 0.48 10.8 0.1 2.6 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) SIKE PF05769.11 RLN92734.1 - 0.25 11.2 7.2 0.57 10.1 1.1 3.0 1 1 1 2 2 2 0 SIKE family AAA_30 PF13604.6 RLN92734.1 - 0.28 10.9 1.0 3.2 7.4 0.3 2.6 2 0 0 2 2 2 0 AAA domain Allexi_40kDa PF05549.11 RLN92734.1 - 1.2 8.6 3.7 1.3 8.5 0.2 2.7 3 0 0 3 3 3 0 Allexivirus 40kDa protein Trimer_CC PF08954.11 RLN92735.1 - 1 9.0 5.5 0.46 10.1 0.7 3.2 2 0 0 2 2 2 0 Trimerisation motif SAPS PF04499.15 RLN92738.1 - 2.2e-06 26.8 0.0 4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein SSP160 PF06933.11 RLN92738.1 - 0.17 10.0 4.2 0.28 9.4 4.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 WW PF00397.26 RLN92739.1 - 4.4e-15 55.5 15.2 1.5e-08 34.6 1.3 2.7 2 0 0 2 2 2 2 WW domain EF-hand_1 PF00036.32 RLN92739.1 - 5.7e-12 44.3 1.0 6.2e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN92739.1 - 9.7e-11 40.7 1.3 0.00012 21.8 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RLN92739.1 - 2.2e-10 40.8 0.4 8.2e-10 39.0 0.4 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RLN92739.1 - 2.3e-07 30.6 2.9 8.5e-07 28.7 0.1 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN92739.1 - 1.1e-06 27.8 4.5 0.0016 17.8 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_10 PF14788.6 RLN92739.1 - 0.06 13.2 0.5 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 EF hand DUF2782 PF11191.8 RLN92739.1 - 0.071 13.3 0.0 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2782) LRR_8 PF13855.6 RLN92739.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Leucine rich repeat Glyco_hyd_101C PF17451.2 RLN92739.1 - 0.12 12.7 2.0 2.2 8.6 0.3 2.8 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain IQ PF00612.27 RLN92739.1 - 0.18 11.7 3.3 0.47 10.4 3.3 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif WD40 PF00400.32 RLN92740.1 - 1.9e-12 47.5 8.0 0.0035 18.2 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 RLN92740.1 - 0.048 12.6 0.0 0.2 10.6 0.0 1.9 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Hexapep PF00132.24 RLN92741.1 - 7.9e-21 72.9 24.2 3.1e-07 29.9 0.5 5.8 5 1 1 6 6 6 5 Bacterial transferase hexapeptide (six repeats) Acetyltransf_11 PF13720.6 RLN92741.1 - 2.8e-14 53.3 0.0 4.2e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Hexapep_2 PF14602.6 RLN92741.1 - 0.00011 21.9 18.6 1.4 8.7 0.8 6.7 4 3 2 6 6 6 4 Hexapeptide repeat of succinyl-transferase Bactofilin PF04519.13 RLN92741.1 - 0.00045 20.5 3.5 0.008 16.5 2.0 2.4 2 0 0 2 2 2 1 Polymer-forming cytoskeletal Peptidase_C1 PF00112.23 RLN92742.1 - 3e-52 177.9 14.1 4.8e-52 177.2 14.1 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RLN92742.1 - 0.00024 20.0 0.8 0.13 11.0 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family ABC2_membrane PF01061.24 RLN92743.1 - 5.9e-71 238.2 63.7 8.7e-39 133.1 24.9 2.6 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN92743.1 - 2.9e-35 121.8 0.1 5.8e-17 62.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 RLN92743.1 - 7.5e-08 32.2 3.9 3.2e-06 26.9 0.1 3.5 3 0 0 3 3 2 1 CDR ABC transporter AAA_21 PF13304.6 RLN92743.1 - 1.6e-07 31.4 0.0 0.14 12.0 0.0 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 RLN92743.1 - 1.9e-07 30.6 0.7 4e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 RLN92743.1 - 2.7e-06 27.8 0.1 0.0073 16.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 RLN92743.1 - 8.6e-06 25.8 1.2 0.033 14.1 0.4 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 RLN92743.1 - 2.2e-05 24.9 0.1 0.11 12.9 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 RLN92743.1 - 3.1e-05 23.6 4.4 0.027 14.2 0.6 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN92743.1 - 3.2e-05 24.2 0.1 0.07 13.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 RLN92743.1 - 3.5e-05 23.5 0.1 0.1 12.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RLN92743.1 - 0.00042 20.9 1.1 0.26 11.8 0.1 2.3 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 RLN92743.1 - 0.00079 19.1 0.5 0.94 9.0 0.0 2.7 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 RLN92743.1 - 0.001 19.3 0.1 0.79 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RLN92743.1 - 0.0014 19.2 0.0 2.1 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RLN92743.1 - 0.0014 18.4 2.0 0.87 9.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 RLN92743.1 - 0.0033 16.9 1.7 1.5 8.2 0.2 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 RLN92743.1 - 0.0037 17.3 0.1 0.12 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) PDR_assoc PF08370.11 RLN92743.1 - 0.0038 16.9 0.2 0.0038 16.9 0.2 3.3 3 0 0 3 3 2 1 Plant PDR ABC transporter associated Roc PF08477.13 RLN92743.1 - 0.0047 17.1 0.3 0.56 10.4 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 RLN92743.1 - 0.0079 16.2 0.5 6.5 6.8 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 RLN92743.1 - 0.0088 16.0 3.2 0.79 9.6 0.1 2.8 2 0 0 2 2 2 1 NACHT domain PduV-EutP PF10662.9 RLN92743.1 - 0.022 14.5 1.4 6.4 6.5 0.3 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 RLN92743.1 - 0.024 14.4 0.5 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 RLN92743.1 - 0.035 14.2 1.8 3.8 7.6 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_19 PF13245.6 RLN92743.1 - 0.042 14.2 0.0 2.3 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 RLN92743.1 - 0.067 12.9 0.4 4.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 RLN92743.1 - 0.099 13.0 0.5 11 6.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase FeoB_N PF02421.18 RLN92743.1 - 0.11 12.0 0.5 9.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Ploopntkinase3 PF18751.1 RLN92743.1 - 0.16 11.9 0.6 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 RLN92743.1 - 0.21 11.8 1.6 28 4.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 RLN92743.1 - 0.32 10.3 0.8 17 4.7 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Mg_chelatase PF01078.21 RLN92743.1 - 0.34 10.3 0.7 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF87 PF01935.17 RLN92743.1 - 3.3 7.8 5.0 29 4.7 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain ABC2_membrane PF01061.24 RLN92744.1 - 5.3e-66 222.0 73.9 4.7e-39 134.0 27.2 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN92744.1 - 8e-35 120.3 0.1 3e-17 63.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN92744.1 - 1.3e-07 31.8 0.8 0.19 11.5 0.0 3.4 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN92744.1 - 5.9e-07 30.0 0.0 0.022 15.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 RLN92744.1 - 4.1e-06 26.8 1.0 0.024 14.5 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 RLN92744.1 - 2.4e-05 24.0 4.0 0.025 14.3 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN92744.1 - 3.2e-05 24.5 0.1 0.2 12.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RLN92744.1 - 3.3e-05 24.2 0.0 0.11 12.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 RLN92744.1 - 3.8e-05 23.2 0.5 0.64 9.4 0.2 3.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain PDR_CDR PF06422.12 RLN92744.1 - 6.7e-05 22.7 11.4 0.00057 19.7 0.4 3.8 3 0 0 3 3 2 2 CDR ABC transporter AAA_25 PF13481.6 RLN92744.1 - 7.1e-05 22.5 0.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 RLN92744.1 - 0.00076 19.9 0.3 1 9.8 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 RLN92744.1 - 0.0012 18.6 0.5 1.7 8.4 0.1 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN92744.1 - 0.0015 17.8 0.8 0.16 11.2 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin PDR_assoc PF08370.11 RLN92744.1 - 0.0017 18.1 0.3 0.0017 18.1 0.3 3.5 3 0 0 3 3 2 1 Plant PDR ABC transporter associated cobW PF02492.19 RLN92744.1 - 0.0043 16.7 2.3 2 8.0 0.0 2.9 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 RLN92744.1 - 0.0055 17.3 0.0 3.5 8.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 RLN92744.1 - 0.0099 15.8 3.1 1.8 8.5 0.1 2.8 2 0 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 RLN92744.1 - 0.011 15.6 0.0 3.8 7.3 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 RLN92744.1 - 0.016 15.3 0.9 3.2 7.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Roc PF08477.13 RLN92744.1 - 0.017 15.4 0.3 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 RLN92744.1 - 0.036 14.1 0.6 5.3 7.1 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 RLN92744.1 - 0.054 13.3 2.2 5.9 6.6 0.3 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 RLN92744.1 - 0.058 13.6 1.6 7.9 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 RLN92744.1 - 0.06 13.3 0.3 1.9 8.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RLN92744.1 - 0.066 12.9 0.3 5 6.9 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 RLN92744.1 - 0.07 12.8 1.6 5.4 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 RLN92744.1 - 0.11 11.8 0.8 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_33 PF13671.6 RLN92744.1 - 0.11 12.6 0.4 11 6.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RLN92744.1 - 0.14 12.6 0.5 26 5.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase PRK PF00485.18 RLN92744.1 - 0.19 11.4 0.1 17 5.1 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Ploopntkinase3 PF18751.1 RLN92744.1 - 0.3 11.0 0.8 3.1 7.7 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF87 PF01935.17 RLN92744.1 - 0.83 9.7 3.2 22 5.0 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain ABC2_membrane PF01061.24 RLN92745.1 - 3.2e-61 206.4 75.0 1.2e-36 126.1 27.0 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN92745.1 - 9.6e-34 116.8 0.1 3.2e-17 63.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 RLN92745.1 - 2.3e-07 30.6 8.4 0.00012 21.9 0.3 3.8 2 1 1 3 3 3 2 CDR ABC transporter AAA_21 PF13304.6 RLN92745.1 - 9e-07 29.0 0.6 0.22 11.3 0.0 3.5 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN92745.1 - 8.4e-06 25.8 1.0 0.022 14.7 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 RLN92745.1 - 1.8e-05 25.2 0.1 0.19 12.1 0.0 2.6 3 0 0 3 3 2 2 AAA ATPase domain AAA_25 PF13481.6 RLN92745.1 - 2.4e-05 24.0 0.1 0.11 12.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RLN92745.1 - 0.00012 22.4 0.1 0.42 10.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain PDR_assoc PF08370.11 RLN92745.1 - 0.00014 21.5 0.3 0.00014 21.5 0.3 3.4 3 0 0 3 3 2 1 Plant PDR ABC transporter associated AAA_29 PF13555.6 RLN92745.1 - 0.00017 21.3 4.2 0.025 14.3 0.4 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 RLN92745.1 - 0.0002 20.9 1.5 0.49 9.8 0.3 3.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RLN92745.1 - 0.0009 19.8 0.5 0.15 12.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RLN92745.1 - 0.0016 18.9 0.5 2.3 8.6 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 RLN92745.1 - 0.0018 18.0 0.5 1.6 8.4 0.1 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN92745.1 - 0.0061 15.9 1.2 0.53 9.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 RLN92745.1 - 0.012 16.2 0.0 9.1 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RLN92745.1 - 0.018 15.0 2.8 3.1 7.7 0.1 2.6 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 RLN92745.1 - 0.027 14.4 0.0 4.5 7.1 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 RLN92745.1 - 0.032 14.2 1.0 5.4 7.0 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 RLN92745.1 - 0.037 14.1 0.8 9.5 6.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Roc PF08477.13 RLN92745.1 - 0.038 14.2 0.3 4.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 RLN92745.1 - 0.038 13.7 0.8 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 RLN92745.1 - 0.062 13.0 0.1 12 5.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family cobW PF02492.19 RLN92745.1 - 0.08 12.5 2.5 4.5 6.8 0.7 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 RLN92745.1 - 0.09 12.9 0.6 10 6.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RLN92745.1 - 0.11 12.9 0.7 18 5.7 0.1 2.6 2 0 0 2 2 2 0 RNA helicase RuvB_N PF05496.12 RLN92745.1 - 0.14 11.9 0.2 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 RLN92745.1 - 0.34 10.4 2.0 1.7 8.1 0.1 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase PF06745.13 RLN92745.1 - 0.35 10.2 1.6 2.3 7.5 0.1 2.2 2 0 0 2 2 2 0 KaiC PduV-EutP PF10662.9 RLN92745.1 - 0.37 10.5 2.7 5.9 6.6 0.3 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 RLN92745.1 - 0.96 9.5 3.7 19 5.3 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Sulfotransfer_1 PF00685.27 RLN92746.1 - 3.8e-09 36.4 0.3 1.9e-08 34.2 0.3 2.0 1 1 0 1 1 1 1 Sulfotransferase domain ABC2_membrane PF01061.24 RLN92746.1 - 1.3e-08 34.5 8.3 2e-08 33.9 8.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter Sulfotransfer_3 PF13469.6 RLN92746.1 - 2e-08 34.9 0.2 5.3e-06 27.0 0.2 2.4 2 0 0 2 2 2 2 Sulfotransferase family Phage_holin_3_6 PF07332.11 RLN92746.1 - 0.26 11.3 9.4 0.44 10.6 9.4 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III C2 PF00168.30 RLN92748.1 - 7.5e-08 32.6 0.0 2e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 C2 domain SnoaL_2 PF12680.7 RLN92748.1 - 0.012 16.3 1.1 0.04 14.6 0.0 2.3 2 1 0 2 2 2 0 SnoaL-like domain NUDIX PF00293.28 RLN92749.1 - 2.4e-16 60.0 0.1 4.2e-16 59.2 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain Bcr-Abl_Oligo PF09036.10 RLN92749.1 - 0.022 14.8 0.1 0.083 12.9 0.1 1.9 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain 3-PAP PF12578.8 RLN92749.1 - 0.054 13.2 0.4 0.13 12.0 0.2 1.7 2 0 0 2 2 2 0 Myotubularin-associated protein Peptidase_A21 PF03566.13 RLN92749.1 - 0.12 10.6 0.0 0.16 10.2 0.0 1.1 1 0 0 1 1 1 0 Peptidase family A21 ER_lumen_recept PF00810.18 RLN92750.1 - 8.3e-49 166.2 7.3 8.3e-49 166.2 7.3 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 RLN92750.1 - 0.045 13.5 0.1 0.045 13.5 0.1 2.8 2 1 1 3 3 3 0 PQ loop repeat AAA_26 PF13500.6 RLN92751.1 - 4.5e-41 140.9 0.0 4.9e-40 137.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 RLN92751.1 - 1.5e-06 28.3 0.0 7.2e-06 26.1 0.0 2.1 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain DRTGG PF07085.12 RLN92751.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 DRTGG domain DRMBL PF07522.14 RLN92752.1 - 1e-24 86.8 0.0 2.5e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase zinc-ribbons_6 PF07191.12 RLN92752.1 - 0.06 13.3 1.5 0.46 10.5 0.4 2.6 2 0 0 2 2 2 0 zinc-ribbons zf-Mss51 PF13824.6 RLN92752.1 - 0.13 12.4 2.5 15 5.7 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Ubiquitin_2 PF14560.6 RLN92752.1 - 0.15 12.5 0.0 0.42 11.1 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain Lar_restr_allev PF14354.6 RLN92752.1 - 0.18 12.2 4.2 10 6.6 1.8 3.4 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-C2H2_6 PF13912.6 RLN92752.1 - 0.24 11.4 0.9 40 4.4 0.1 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger RNHCP PF12647.7 RLN92752.1 - 0.34 10.9 6.1 20 5.2 0.5 3.7 3 1 1 4 4 4 0 RNHCP domain zf-Di19 PF05605.12 RLN92752.1 - 0.4 11.0 2.2 35 4.8 0.0 3.4 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 RLN92752.1 - 0.61 11.1 2.6 39 5.4 0.2 4.0 3 1 1 4 4 3 0 C2H2-type zinc finger BIR PF00653.21 RLN92752.1 - 0.76 10.5 4.7 8.7 7.1 0.1 3.8 3 1 1 4 4 3 0 Inhibitor of Apoptosis domain zf-RING_2 PF13639.6 RLN92752.1 - 2.1 8.8 7.0 36 4.8 1.5 4.2 4 1 0 4 4 4 0 Ring finger domain ParcG PF10274.9 RLN92753.1 - 8.6e-40 136.8 0.0 1e-39 136.5 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein DNA_pol_A_exo1 PF01612.20 RLN92754.1 - 1.7e-22 80.0 0.2 8.5e-11 41.9 0.1 2.5 2 0 0 2 2 2 2 3'-5' exonuclease FHA PF00498.26 RLN92755.1 - 5.1e-16 58.8 0.0 8e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RLN92755.1 - 6.8e-06 26.3 0.1 0.00067 19.9 0.1 2.1 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain GrpB PF04229.14 RLN92755.1 - 0.032 14.4 0.2 0.32 11.2 0.1 1.9 2 0 0 2 2 2 0 GrpB protein DUF4156 PF13698.6 RLN92757.1 - 0.16 12.3 0.2 0.35 11.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4156) Ribosomal_L7Ae PF01248.26 RLN92758.1 - 3.4e-26 90.8 0.0 4.7e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 RLN92758.1 - 4.6e-05 23.2 0.0 6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 RLN92758.1 - 0.004 17.2 0.0 0.0043 17.1 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 Octopine_DH PF02317.17 RLN92759.1 - 5.2e-38 130.5 0.0 1.3e-37 129.2 0.0 1.7 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain TPR_1 PF00515.28 RLN92759.1 - 3.7e-28 96.2 26.2 3.6e-05 23.4 0.2 12.2 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_2 PF07719.17 RLN92759.1 - 2e-27 93.1 23.3 0.0015 18.5 0.0 11.9 11 1 0 11 11 11 6 Tetratricopeptide repeat TPR_11 PF13414.6 RLN92759.1 - 1.2e-25 88.9 3.8 0.00022 20.8 0.0 9.5 7 3 3 10 10 10 6 TPR repeat TPR_17 PF13431.6 RLN92759.1 - 3.3e-20 71.0 0.9 0.0018 18.5 0.0 7.3 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 RLN92759.1 - 1.2e-16 59.4 8.6 0.0018 18.2 0.0 8.5 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN92759.1 - 3.4e-16 58.6 13.0 0.0048 17.6 0.0 10.4 7 4 4 12 12 10 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN92759.1 - 2.4e-15 55.4 26.5 0.098 12.9 0.3 11.1 12 1 0 12 12 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 RLN92759.1 - 1.6e-13 50.9 13.5 0.0078 16.7 0.0 6.5 6 1 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 RLN92759.1 - 4.1e-13 49.7 5.8 0.037 14.7 0.0 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 RLN92759.1 - 9.5e-13 48.2 13.2 0.35 11.2 0.0 6.9 4 2 1 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 RLN92759.1 - 8.2e-09 35.5 2.3 0.00037 20.6 0.0 5.7 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN92759.1 - 2.7e-05 23.9 17.7 0.39 10.7 0.0 8.4 9 0 0 9 9 9 1 Tetratricopeptide repeat Ada3 PF10198.9 RLN92759.1 - 0.0015 18.7 0.1 0.0088 16.2 0.0 2.3 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 TAtT PF16811.5 RLN92759.1 - 0.0038 16.6 0.7 0.011 15.1 0.3 1.9 2 0 0 2 2 2 1 TRAP transporter T-component F420_oxidored PF03807.17 RLN92759.1 - 0.011 16.4 0.1 0.032 14.8 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 RLN92759.1 - 0.013 15.1 0.2 0.039 13.5 0.2 1.7 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 RLN92759.1 - 0.024 14.3 0.1 0.058 13.0 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Siah-Interact_N PF09032.11 RLN92759.1 - 0.067 13.5 0.1 0.21 11.9 0.1 1.8 1 0 0 1 1 1 0 Siah interacting protein, N terminal TPR_3 PF07720.12 RLN92759.1 - 0.072 13.1 1.5 52 4.0 0.2 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 RLN92759.1 - 0.084 11.8 6.4 1.1 8.0 0.3 3.9 3 2 1 4 4 4 0 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 RLN92759.1 - 0.11 13.2 1.0 62 4.7 0.0 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat YjeF_N PF03853.15 RLN92759.1 - 0.11 12.3 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 YjeF-related protein N-terminus TPR_MalT PF17874.1 RLN92759.1 - 0.47 9.8 4.0 2.1 7.6 0.1 2.8 2 1 0 2 2 2 0 MalT-like TPR region ANAPC3 PF12895.7 RLN92759.1 - 2 8.7 17.3 0.5 10.6 0.9 4.8 5 1 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 RLN92759.1 - 5.6 7.1 13.7 1.1 9.4 0.7 5.1 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain TPR_21 PF09976.9 RLN92759.1 - 6 6.5 10.1 3.3 7.4 0.2 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat-like domain Glyco_transf_28 PF03033.20 RLN92760.1 - 0.0018 18.3 0.0 0.0041 17.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain BSP_II PF05432.11 RLN92760.1 - 1.8 8.2 28.6 0.019 14.7 21.1 1.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) THF_DHG_CYH PF00763.23 RLN92762.1 - 5.2e-20 71.8 0.0 1.3e-19 70.6 0.0 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 RLN92762.1 - 8.1e-14 51.2 2.4 5.9e-11 41.9 1.1 3.8 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Retrotrans_gag PF03732.17 RLN92763.1 - 9.1e-05 22.7 0.1 0.00019 21.6 0.1 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein RhoGAP PF00620.27 RLN92764.1 - 1.4e-15 57.4 0.0 2.4e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PBD PF00786.28 RLN92764.1 - 3.9e-06 27.1 0.0 7.9e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain Hydrolase_4 PF12146.8 RLN92765.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 POTRA_3 PF17287.2 RLN92766.1 - 0.041 13.3 0.2 0.073 12.5 0.2 1.4 1 0 0 1 1 1 0 POTRA domain Glyco_trans_1_2 PF13524.6 RLN92766.1 - 0.082 13.3 0.1 0.093 13.1 0.1 1.1 1 0 0 1 1 1 0 Glycosyl transferases group 1 Hydrolase_4 PF12146.8 RLN92769.1 - 7.2e-47 159.7 1.1 1.3e-44 152.3 1.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN92769.1 - 2e-10 41.7 0.9 3.5e-10 40.9 0.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN92769.1 - 8.8e-07 28.8 1.2 2e-05 24.4 1.4 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN92769.1 - 0.00016 21.2 0.7 0.25 10.8 0.0 3.1 3 0 0 3 3 3 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 RLN92769.1 - 0.013 15.1 0.0 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) PAF-AH_p_II PF03403.13 RLN92769.1 - 0.088 11.3 0.0 0.18 10.2 0.0 1.5 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II PhoPQ_related PF10142.9 RLN92769.1 - 0.17 10.5 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Abhydrolase_2 PF02230.16 RLN92769.1 - 0.36 10.6 3.7 5.7 6.7 3.2 2.7 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase AMP-binding PF00501.28 RLN92770.1 - 8.2e-94 314.6 0.0 1.1e-93 314.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN92770.1 - 2e-05 25.5 0.3 4.6e-05 24.3 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Oxidored_FMN PF00724.20 RLN92771.1 - 2e-155 517.3 0.0 4.3e-79 266.3 0.0 2.3 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family AMP-binding PF00501.28 RLN92771.1 - 9e-102 340.8 0.1 1.2e-101 340.3 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN92771.1 - 0.012 16.6 1.3 0.023 15.7 0.1 2.1 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain cNMP_binding PF00027.29 RLN92772.1 - 2e-21 75.9 0.0 7.8e-06 25.9 0.0 4.1 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain Elicitin PF00964.17 RLN92773.1 - 2.5e-19 69.2 2.8 3.9e-19 68.5 2.8 1.3 1 0 0 1 1 1 1 Elicitin IMUP PF15761.5 RLN92773.1 - 3.2 8.5 8.6 5.2 7.8 8.6 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF3150 PF11348.8 RLN92775.1 - 0.034 13.4 0.2 0.054 12.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) EF-hand_4 PF12763.7 RLN92775.1 - 0.085 12.8 0.0 0.21 11.5 0.0 1.7 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DUF3450 PF11932.8 RLN92775.1 - 3.2 7.0 9.5 1.8 7.8 3.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 RLN92775.1 - 6.8 5.5 6.7 10 4.9 6.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Band_7 PF01145.25 RLN92778.1 - 2.2e-18 66.9 5.8 3.4e-18 66.3 0.2 3.0 2 1 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 RLN92778.1 - 0.0035 17.1 1.9 0.0077 16.0 0.0 2.1 2 0 0 2 2 2 1 SPFH domain-Band 7 family RNA_pol_Rpb1_5 PF04998.17 RLN92778.1 - 0.013 14.9 3.2 0.022 14.2 3.2 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 YlqD PF11068.8 RLN92778.1 - 0.091 13.1 13.0 0.5 10.7 0.4 3.3 1 1 3 4 4 4 0 YlqD protein Ank_4 PF13637.6 RLN92779.1 - 2.8e-14 53.3 8.4 1.1e-07 32.3 0.8 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN92779.1 - 1.9e-10 41.2 0.4 4.9e-10 39.9 0.4 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN92779.1 - 3e-09 37.0 1.8 1.5e-07 31.5 0.3 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN92779.1 - 1.6e-08 34.1 0.2 0.0048 17.3 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 RLN92779.1 - 7.9e-07 29.3 2.6 0.03 14.8 0.3 3.4 4 0 0 4 4 4 2 Ankyrin repeat Myb_DNA-bind_4 PF13837.6 RLN92780.1 - 4.1e-06 27.1 0.6 0.0079 16.6 0.1 2.6 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain KIF1B PF12423.8 RLN92780.1 - 1.8 9.0 10.1 6.3 7.3 0.4 3.9 3 1 1 4 4 4 0 Kinesin protein 1B ECH_1 PF00378.20 RLN92781.1 - 1.3e-31 109.8 0.6 1.8e-31 109.4 0.6 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RLN92781.1 - 1.2e-17 64.4 0.4 1.5e-17 64.2 0.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 RLN92782.1 - 6.3e-32 110.9 0.0 8.1e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RLN92782.1 - 4.2e-17 62.6 0.1 7.3e-17 61.9 0.1 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Band_7 PF01145.25 RLN92783.1 - 2.4e-21 76.5 0.0 2.4e-21 76.5 0.0 2.8 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF3015 PF11220.8 RLN92783.1 - 0.14 12.0 3.5 0.39 10.6 3.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) Glyco_hydro_67N PF03648.14 RLN92783.1 - 0.15 12.3 3.3 0.41 11.0 3.1 1.8 1 1 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus DUF5403 PF17395.2 RLN92783.1 - 2.7 8.4 11.1 2.1 8.7 1.7 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5403) Band_7 PF01145.25 RLN92784.1 - 1.7e-17 64.0 4.9 1.6e-07 31.5 0.1 3.1 3 0 0 3 3 3 2 SPFH domain / Band 7 family Band_7_1 PF13421.6 RLN92784.1 - 0.0019 18.0 2.5 0.0065 16.2 0.0 2.2 2 0 0 2 2 2 1 SPFH domain-Band 7 family Orthopox_A36R PF05950.11 RLN92784.1 - 0.025 14.7 0.7 0.047 13.8 0.7 1.4 1 0 0 1 1 1 0 Orthopoxvirus A36R protein FapA PF03961.13 RLN92784.1 - 0.27 9.8 9.5 0.44 9.1 9.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Band_7 PF01145.25 RLN92785.1 - 6.9e-24 84.8 0.0 6.9e-24 84.8 0.0 2.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 RLN92785.1 - 0.0044 16.7 0.1 0.019 14.6 0.0 2.0 2 1 0 2 2 2 1 SPFH domain-Band 7 family HTS PF04204.16 RLN92785.1 - 0.008 15.1 0.4 0.014 14.4 0.4 1.4 1 0 0 1 1 1 1 Homoserine O-succinyltransferase Imm31 PF15591.6 RLN92785.1 - 0.13 12.1 0.0 0.39 10.6 0.0 1.8 1 0 0 1 1 1 0 Immunity protein 31 Arm PF00514.23 RLN92786.1 - 8e-55 181.3 9.8 4.9e-08 32.7 0.0 9.8 10 0 0 10 10 9 9 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN92786.1 - 2.9e-11 42.6 7.6 7.8 7.1 0.0 9.0 9 0 0 9 9 9 1 HEAT repeat HEAT_EZ PF13513.6 RLN92786.1 - 7.2e-09 36.0 19.8 0.0018 18.8 0.3 6.6 2 2 6 8 8 8 4 HEAT-like repeat HEAT_PBS PF03130.16 RLN92786.1 - 1.3e-08 34.7 25.8 2 9.3 0.0 10.0 10 1 0 10 10 10 2 PBS lyase HEAT-like repeat HEAT_2 PF13646.6 RLN92786.1 - 4.6e-08 33.4 27.0 0.0043 17.4 2.7 5.9 2 2 5 7 7 7 5 HEAT repeats Atx10homo_assoc PF09759.9 RLN92786.1 - 9e-07 28.8 2.3 0.11 12.5 0.1 4.8 3 2 2 5 5 5 2 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 RLN92786.1 - 1e-06 28.5 0.2 1.4 8.4 0.0 4.2 1 1 2 4 4 4 4 Armadillo-like UNC45-central PF11701.8 RLN92786.1 - 0.00068 19.6 0.1 3.9 7.4 0.0 4.1 2 1 2 4 4 4 1 Myosin-binding striated muscle assembly central DUF294_C PF10335.9 RLN92786.1 - 0.0011 18.7 1.5 11 5.8 0.0 5.3 3 3 2 6 6 6 0 Putative nucleotidyltransferase substrate binding domain DUF4402 PF14352.6 RLN92786.1 - 0.0026 18.4 1.0 96 3.6 0.0 4.6 3 2 2 5 5 5 0 Domain of unknown function (DUF4402) V-ATPase_H_N PF03224.14 RLN92786.1 - 0.0041 16.4 0.0 0.039 13.2 0.0 2.3 1 1 0 1 1 1 1 V-ATPase subunit H Csc2 PF18320.1 RLN92786.1 - 0.052 12.5 0.0 0.089 11.7 0.0 1.4 1 0 0 1 1 1 0 Csc2 Crispr DUF397 PF04149.12 RLN92786.1 - 0.091 12.8 2.8 5.8 7.1 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF397) AvrL567-A PF11529.8 RLN92786.1 - 0.11 12.7 0.4 96 3.2 0.0 4.1 3 2 2 5 5 5 0 Melampsora lini avirulence protein AvrL567-A Aconitase_B_N PF11791.8 RLN92786.1 - 0.29 11.2 4.9 4.7 7.3 0.7 4.4 3 1 1 4 4 4 0 Aconitate B N-terminal domain NRD1_2 PF01995.16 RLN92786.1 - 0.35 10.1 2.2 15 4.8 0.0 4.0 4 1 1 5 5 5 0 NrpR regulatory domains NRD1 and 2 Nuc_N PF14448.6 RLN92786.1 - 0.42 10.5 3.8 18 5.2 0.0 4.7 7 0 0 7 7 7 0 Nuclease N terminal ubiquitin PF00240.23 RLN92787.1 - 0.033 13.9 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin family Dscam_C PF12355.8 RLN92790.1 - 0.77 10.7 4.5 0.35 11.8 1.4 2.0 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal HTH_Tnp_Tc5 PF03221.16 RLN92791.1 - 0.00083 19.3 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 RLN92791.1 - 0.0035 16.9 0.1 0.01 15.4 0.0 1.9 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 RLN92791.1 - 0.0044 17.1 0.2 0.29 11.3 0.0 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_IclR PF09339.10 RLN92791.1 - 0.013 15.3 0.1 0.033 14.0 0.1 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain MarR_2 PF12802.7 RLN92791.1 - 0.034 14.0 0.0 0.091 12.7 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.6 RLN92791.1 - 0.04 13.7 0.0 0.16 11.8 0.0 2.0 1 0 0 1 1 1 0 Homeodomain-like domain HTH_24 PF13412.6 RLN92791.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Tnp_4 PF13613.6 RLN92791.1 - 0.067 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR PF01047.22 RLN92791.1 - 0.071 13.0 0.0 0.25 11.3 0.0 1.9 1 0 0 1 1 1 0 MarR family HTH_psq PF05225.16 RLN92791.1 - 0.09 12.5 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_Tnp_ISL3 PF13542.6 RLN92791.1 - 0.13 11.7 0.0 0.53 9.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Ldt_C PF17969.1 RLN92793.1 - 2.5 8.9 5.4 4.4 8.1 0.1 3.3 3 0 0 3 3 3 0 L,D-transpeptidase C-terminal domain Cu-oxidase_3 PF07732.15 RLN92795.1 - 8.1e-23 80.7 0.8 4.4e-21 75.1 0.6 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 RLN92795.1 - 1.1e-15 57.6 7.7 3.5e-13 49.4 1.8 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 RLN92795.1 - 0.0034 17.5 0.0 0.27 11.3 0.0 2.5 2 0 0 2 2 2 1 Multicopper oxidase Orbi_NS3 PF01616.16 RLN92795.1 - 0.17 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Orbivirus NS3 TFIIA PF03153.13 RLN92795.1 - 0.6 10.0 8.0 0.83 9.6 8.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.12 RLN92795.1 - 5.8 6.2 14.8 10 5.3 14.8 1.4 1 0 0 1 1 1 0 NOA36 protein UCH PF00443.29 RLN92796.1 - 8.5e-45 153.2 0.0 1.5e-44 152.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Metallophos_C PF14008.6 RLN92796.1 - 9.7e-18 64.8 0.1 3.7e-17 62.9 0.1 2.0 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 RLN92796.1 - 4.4e-13 50.2 0.1 1.5e-12 48.5 0.0 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase UCH_1 PF13423.6 RLN92796.1 - 7.6e-07 29.0 0.5 4.8e-05 23.1 0.5 2.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 RLN92796.1 - 0.0032 17.2 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.6 RLN92796.1 - 0.013 15.0 0.6 0.065 12.7 0.1 2.2 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase ZZ PF00569.17 RLN92797.1 - 0.0028 17.4 3.0 0.0044 16.8 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type MMR_HSR1 PF01926.23 RLN92798.1 - 1.1e-15 57.7 0.0 2.5e-13 50.1 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN92798.1 - 4.5e-09 36.0 0.1 9.1e-06 25.3 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RLN92798.1 - 8.8e-06 25.7 0.1 0.00081 19.3 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 RLN92798.1 - 0.00022 21.3 0.1 0.00022 21.3 0.1 3.0 3 1 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 RLN92798.1 - 4.7 6.7 10.2 2.5 7.6 1.0 3.1 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain ANAPC4_WD40 PF12894.7 RLN92799.1 - 8.6e-15 54.8 0.0 0.00066 19.9 0.0 6.7 4 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 RLN92799.1 - 1.3e-08 34.9 24.5 0.027 14.3 0.1 9.2 6 3 2 9 9 9 3 Region in Clathrin and VPS WD40 PF00400.32 RLN92799.1 - 6.9e-07 29.9 0.4 3.2 8.8 0.0 6.0 6 0 0 6 6 6 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 RLN92799.1 - 1.3e-06 27.8 13.8 0.00017 20.8 0.5 5.4 5 2 2 7 7 7 2 Coatomer WD associated region PPR PF01535.20 RLN92799.1 - 0.00041 20.4 3.9 19 5.8 0.1 7.3 7 0 0 7 7 7 0 PPR repeat TPR_1 PF00515.28 RLN92799.1 - 0.088 12.7 30.9 1 9.3 0.1 10.1 10 1 1 11 11 11 0 Tetratricopeptide repeat TPR_8 PF13181.6 RLN92799.1 - 0.21 11.9 20.7 3.1 8.2 0.4 9.1 9 1 0 9 9 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 RLN92799.1 - 0.49 10.5 26.9 5.2 7.3 1.0 9.9 10 2 0 10 10 9 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN92799.1 - 0.57 10.4 49.0 0.053 13.6 0.4 11.7 13 0 0 13 13 12 0 Tetratricopeptide repeat PPR_2 PF13041.6 RLN92799.1 - 1.5 9.1 5.7 51 4.2 0.0 5.6 5 1 1 6 6 6 0 PPR repeat family DUF410 PF04190.13 RLN92799.1 - 1.6 8.5 14.9 0.09 12.6 1.7 4.4 3 1 0 4 4 4 0 Protein of unknown function (DUF410) TPR_11 PF13414.6 RLN92799.1 - 2.1 8.1 6.2 4.2 7.1 0.0 4.9 5 0 0 5 5 5 0 TPR repeat Sec16_C PF12931.7 RLN92799.1 - 2.8 7.5 13.4 3 7.4 0.1 4.9 4 2 2 6 6 6 0 Sec23-binding domain of Sec16 DZR PF12773.7 RLN92799.1 - 3.3 7.8 8.5 9.5 6.3 8.4 1.9 1 1 0 1 1 1 0 Double zinc ribbon Methyltransf_16 PF10294.9 RLN92800.1 - 1.2e-09 38.2 0.0 1.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 RLN92800.1 - 0.0014 18.1 0.1 0.002 17.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GPI2 PF06432.11 RLN92801.1 - 1.5e-23 83.7 7.1 1.9e-23 83.3 7.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase PRA1 PF03208.19 RLN92801.1 - 0.17 11.5 7.1 0.24 11.0 7.1 1.2 1 0 0 1 1 1 0 PRA1 family protein CPP1-like PF11833.8 RLN92801.1 - 1.9 8.1 5.2 4.4 6.9 0.4 2.0 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Myb_DNA-binding PF00249.31 RLN92802.1 - 3.7e-10 39.8 0.1 7.7e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN92802.1 - 0.014 15.6 0.8 0.028 14.7 0.8 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain PBP1_TM PF14812.6 RLN92802.1 - 0.26 11.7 4.7 5.5 7.4 0.1 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 RLN92802.1 - 0.94 9.1 5.0 10 5.8 1.8 2.3 2 0 0 2 2 2 0 FAM176 family Baculo_PEP_C PF04513.12 RLN92803.1 - 0.032 14.3 0.1 4.2 7.4 0.0 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus tRNA_int_end_N2 PF12928.7 RLN92804.1 - 1.9e-07 31.1 0.1 6.3e-07 29.5 0.1 1.9 1 1 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 RLN92804.1 - 0.0058 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Sugar_tr PF00083.24 RLN92805.1 - 1.9e-38 132.5 6.0 2.4e-38 132.2 6.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN92805.1 - 6.2e-16 58.3 20.1 1.4e-15 57.1 20.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 RLN92805.1 - 1.3e-07 30.5 4.0 1.8e-07 30.0 4.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 RLN92805.1 - 7.4e-06 25.5 9.3 1.2e-05 24.8 9.3 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_5 PF05631.14 RLN92805.1 - 0.00058 18.9 2.2 0.00084 18.4 2.2 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM SPW PF03779.14 RLN92805.1 - 0.0091 15.6 3.5 0.49 10.0 0.3 3.1 2 0 0 2 2 2 2 SPW repeat MscL PF01741.18 RLN92805.1 - 0.16 12.3 0.2 0.29 11.4 0.2 1.3 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL cNMP_binding PF00027.29 RLN92807.1 - 1.3e-17 63.6 0.0 7.6e-11 41.9 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PP2C PF00481.21 RLN92807.1 - 4.8e-16 59.2 0.1 1.4e-11 44.6 0.0 2.4 2 1 0 2 2 2 2 Protein phosphatase 2C Pkinase PF00069.25 RLN92807.1 - 2.6e-08 33.5 0.0 2.2e-06 27.3 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92807.1 - 0.0028 17.0 0.1 0.025 13.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase PP2C_2 PF13672.6 RLN92807.1 - 0.017 14.7 0.0 0.41 10.2 0.0 2.4 2 0 0 2 2 2 0 Protein phosphatase 2C GATase_7 PF13537.6 RLN92809.1 - 5.8e-42 142.5 0.0 1.8e-41 140.9 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain Asn_synthase PF00733.21 RLN92809.1 - 4e-39 135.3 0.0 5.4e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_6 PF13522.6 RLN92809.1 - 2.4e-30 105.5 0.0 3.6e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 RLN92809.1 - 1.5e-12 47.5 0.1 3.1e-12 46.4 0.1 1.6 1 1 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 RLN92809.1 - 0.037 13.2 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD synthase tRNA_Me_trans PF03054.16 RLN92809.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Cys_Met_Meta_PP PF01053.20 RLN92811.1 - 4.6e-131 436.9 0.0 5.5e-131 436.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 RLN92811.1 - 5.4e-10 38.8 0.0 1.1e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 RLN92811.1 - 3.6e-06 26.5 0.0 8.4e-06 25.3 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.16 RLN92811.1 - 4.1e-05 22.6 0.0 6.6e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Aminotran_1_2 PF00155.21 RLN92811.1 - 7.4e-05 22.1 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Lipid_DES PF08557.10 RLN92812.1 - 4.2e-18 64.5 1.3 6e-18 64.0 1.3 1.2 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Aldo_ket_red PF00248.21 RLN92816.1 - 5.3e-68 229.4 0.0 5.9e-68 229.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Dimer_Tnp_hAT PF05699.14 RLN92817.1 - 0.018 14.9 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Acyltransferase PF01553.21 RLN92818.1 - 1.6e-14 53.7 0.0 2.4e-13 49.8 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase Metallophos PF00149.28 RLN92819.1 - 1.9e-09 38.4 0.1 2.6e-09 37.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Thioredoxin PF00085.20 RLN92821.1 - 9.9e-09 35.1 0.0 1.4e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 RLN92821.1 - 0.022 13.7 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Phosducin HyaE PF07449.11 RLN92821.1 - 0.026 14.5 0.1 0.045 13.7 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF5570 PF17731.1 RLN92822.1 - 0.012 15.8 0.5 0.012 15.8 0.5 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5570) Lin-8 PF03353.15 RLN92822.1 - 0.8 9.2 5.8 1 8.9 5.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist AAA_5 PF07728.14 RLN92823.1 - 1.7e-83 277.5 0.0 8.6e-24 84.1 0.0 7.1 6 0 0 6 6 6 6 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 RLN92823.1 - 1.5e-24 86.2 9.4 2.9e-12 46.7 0.3 5.0 5 0 0 5 5 3 2 Midasin AAA lid domain AAA_3 PF07726.11 RLN92823.1 - 4.1e-17 62.3 0.0 2.1e-06 27.6 0.0 5.4 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 RLN92823.1 - 7.2e-15 55.6 3.3 0.00064 20.1 0.0 6.1 5 1 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 RLN92823.1 - 1.1e-12 47.8 0.0 0.0014 18.1 0.0 4.5 4 0 0 4 4 4 3 P-loop containing dynein motor region Dynein_heavy PF03028.15 RLN92823.1 - 2.6e-12 46.9 0.0 0.0078 16.3 0.0 4.9 4 0 0 4 4 4 3 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 RLN92823.1 - 2.8e-10 40.9 25.9 0.0022 18.4 0.1 7.7 8 1 1 9 9 6 4 AAA ATPase domain AAA_22 PF13401.6 RLN92823.1 - 5.7e-10 39.6 7.1 0.016 15.5 0.0 6.7 7 0 0 7 7 5 2 AAA domain AAA_6 PF12774.7 RLN92823.1 - 2.1e-07 30.2 0.1 0.24 10.3 0.0 5.9 6 0 0 6 6 6 2 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 RLN92823.1 - 5.6e-07 29.6 0.1 1.2 9.1 0.0 4.0 4 0 0 4 4 4 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 RLN92823.1 - 1.5e-06 28.0 0.0 0.07 12.8 0.0 4.2 4 0 0 4 4 3 1 Sigma-54 interaction domain AAA_28 PF13521.6 RLN92823.1 - 1.6e-06 28.4 4.8 0.21 11.8 0.0 4.8 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 RLN92823.1 - 3e-06 27.8 12.6 0.11 13.1 0.0 6.4 6 0 0 6 6 4 2 AAA domain AAA_14 PF13173.6 RLN92823.1 - 3.2e-06 27.2 0.0 0.22 11.6 0.0 5.1 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.6 RLN92823.1 - 4.1e-06 27.0 0.4 0.7 10.0 0.0 5.1 4 0 0 4 4 4 1 AAA domain T2SSE PF00437.20 RLN92823.1 - 1.1e-05 24.6 0.0 0.052 12.6 0.0 4.4 5 0 0 5 5 5 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 RLN92823.1 - 1.2e-05 24.8 5.5 0.2 11.0 0.1 6.2 4 2 1 5 5 5 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 RLN92823.1 - 1.8e-05 24.4 1.1 0.88 9.1 0.0 4.6 4 0 0 4 4 4 1 AAA domain RuvB_N PF05496.12 RLN92823.1 - 4.9e-05 23.1 0.3 18 5.0 0.0 5.5 5 0 0 5 5 5 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 RLN92823.1 - 6.8e-05 22.2 2.3 1.4 8.2 0.0 4.9 5 0 0 5 5 5 1 Zeta toxin AAA_8 PF12780.7 RLN92823.1 - 0.00019 20.8 0.0 1.5 8.1 0.0 4.3 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 NACHT PF05729.12 RLN92823.1 - 0.00039 20.4 0.3 2 8.3 0.0 4.5 4 0 0 4 4 4 1 NACHT domain RNA_helicase PF00910.22 RLN92823.1 - 0.00084 19.7 0.2 31 5.0 0.0 4.2 4 0 0 4 4 3 0 RNA helicase RsgA_GTPase PF03193.16 RLN92823.1 - 0.0015 18.5 2.2 1.4 8.8 0.0 4.2 5 0 0 5 5 3 1 RsgA GTPase Sigma54_activ_2 PF14532.6 RLN92823.1 - 0.0015 18.6 0.1 0.49 10.5 0.0 4.4 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_lid_5 PF17865.1 RLN92823.1 - 0.0044 17.1 4.2 0.0073 16.4 0.1 3.4 3 0 0 3 3 3 1 Midasin AAA lid domain ABC_tran PF00005.27 RLN92823.1 - 0.0055 17.2 11.3 0.44 11.1 0.0 5.9 6 0 0 6 6 4 1 ABC transporter PduV-EutP PF10662.9 RLN92823.1 - 0.0075 16.0 0.1 0.53 10.0 0.0 3.5 4 0 0 4 4 3 1 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 RLN92823.1 - 0.0091 15.7 0.0 8.6 6.1 0.0 3.8 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF815 PF05673.13 RLN92823.1 - 0.019 14.1 0.0 2.6 7.1 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 RLN92823.1 - 0.025 14.6 0.5 11 6.2 0.0 4.1 4 0 0 4 4 4 0 50S ribosome-binding GTPase Rad17 PF03215.15 RLN92823.1 - 0.11 12.4 0.4 12 5.7 0.0 3.8 4 0 0 4 4 4 0 Rad17 P-loop domain Roc PF08477.13 RLN92823.1 - 0.23 11.7 1.2 79 3.5 0.0 4.1 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 RLN92823.1 - 0.26 10.9 2.0 61 3.2 0.0 4.4 5 0 0 5 5 5 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 RLN92823.1 - 0.27 11.2 0.9 49 3.8 0.0 3.7 3 0 0 3 3 3 0 NTPase Peptidase_M15_2 PF05951.13 RLN92823.1 - 0.29 10.8 1.7 6.2 6.5 0.0 3.6 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF882) AAA_19 PF13245.6 RLN92823.1 - 0.4 11.0 5.5 9.3 6.6 0.0 4.7 6 0 0 6 6 3 0 AAA domain Snapin_Pallidin PF14712.6 RLN92824.1 - 1.3e-17 64.0 6.0 2.4e-17 63.1 6.0 1.5 1 0 0 1 1 1 1 Snapin/Pallidin Pribosyl_synth PF14572.6 RLN92824.1 - 0.018 15.1 2.4 0.039 14.0 0.8 2.2 2 1 0 2 2 2 0 Phosphoribosyl synthetase-associated domain YabA PF06156.13 RLN92824.1 - 3.8 8.2 6.0 2.4 8.9 2.0 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Med21 PF11221.8 RLN92824.1 - 4.4 7.5 16.8 3.8 7.8 7.7 3.9 2 2 0 2 2 2 0 Subunit 21 of Mediator complex Cyt-b5 PF00173.28 RLN92825.1 - 4.2e-15 55.6 0.0 6.1e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Crystall_3 PF08964.10 RLN92827.1 - 0.091 12.9 0.6 2.7 8.2 0.0 2.2 1 1 1 2 2 2 0 Beta/Gamma crystallin Aa_trans PF01490.18 RLN92828.1 - 1.7e-10 40.2 27.9 5.9e-10 38.4 27.9 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein 3HCDH_N PF02737.18 RLN92829.1 - 4.9e-59 199.2 0.0 6.6e-59 198.8 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 RLN92829.1 - 1.7e-30 105.5 0.1 1.6e-29 102.4 0.0 2.3 2 1 1 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 RLN92829.1 - 7.5e-05 23.0 2.3 0.00017 21.8 2.3 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 RLN92829.1 - 0.0014 18.0 0.2 0.0022 17.4 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 RLN92829.1 - 0.0017 17.9 0.1 0.0026 17.4 0.1 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 RLN92829.1 - 0.11 13.1 1.4 0.23 12.0 1.4 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent LIDHydrolase PF10230.9 RLN92831.1 - 6.4e-49 166.9 0.8 8.1e-49 166.6 0.8 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 RLN92831.1 - 6.9e-07 29.2 0.0 2.3e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN92831.1 - 3e-06 26.7 0.8 8e-06 25.3 0.2 1.6 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN92831.1 - 3e-05 24.7 0.3 3e-05 24.7 0.3 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 RLN92831.1 - 0.03 14.2 0.0 0.071 13.0 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase Lipase_3 PF01764.25 RLN92831.1 - 0.07 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) BAAT_C PF08840.11 RLN92831.1 - 0.16 11.9 0.0 0.41 10.5 0.0 1.8 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Phytoreo_P8 PF07124.11 RLN92831.1 - 0.17 10.8 0.1 0.25 10.3 0.1 1.2 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 TCTP PF00838.17 RLN92836.1 - 3.1e-43 148.0 1.6 3.5e-43 147.8 1.6 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein CelTOS PF18659.1 RLN92836.1 - 0.1 13.0 0.0 0.32 11.5 0.0 1.7 1 1 1 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites Apolipoprotein PF01442.18 RLN92836.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2232 PF09991.9 RLN92836.1 - 0.17 11.0 0.2 0.25 10.5 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) bZIP_1 PF00170.21 RLN92837.1 - 5.6e-07 29.6 8.6 2.6e-06 27.4 8.6 2.2 1 0 0 1 1 1 1 bZIP transcription factor NAPRTase PF04095.16 RLN92837.1 - 0.054 13.1 2.8 0.097 12.3 2.8 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family SUIM_assoc PF16619.5 RLN92837.1 - 0.48 10.5 17.0 1.5 9.0 6.3 4.5 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Pkinase_Tyr PF07714.17 RLN92838.1 - 1.3e-26 93.4 0.0 2.3e-15 56.6 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN92838.1 - 2.6e-20 72.9 0.0 9.9e-11 41.5 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain HAP1_N PF04849.13 RLN92838.1 - 0.028 13.6 0.3 0.028 13.6 0.3 2.3 2 0 0 2 2 2 0 HAP1 N-terminal conserved region LRR_4 PF12799.7 RLN92838.1 - 0.04 14.3 0.2 0.37 11.3 0.2 2.4 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) UCMA PF17085.5 RLN92838.1 - 0.16 12.0 3.1 0.13 12.3 0.5 2.2 2 0 0 2 2 2 0 Unique cartilage matrix associated protein HU-CCDC81_euk_2 PF18289.1 RLN92839.1 - 7e-12 45.3 0.0 1.3e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 RLN92839.1 - 4.1e-09 36.5 0.0 1.7e-08 34.5 0.0 2.1 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 Gon7 PF08738.10 RLN92839.1 - 1.3 9.2 6.9 0.094 12.8 1.6 1.9 2 0 0 2 2 2 0 Gon7 family WD40 PF00400.32 RLN92840.1 - 2.3e-11 44.1 1.3 0.045 14.6 0.0 6.0 6 1 0 6 6 6 3 WD domain, G-beta repeat Complex1_LYR PF05347.15 RLN92841.1 - 9.8e-06 25.5 0.2 2e-05 24.5 0.2 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF410 PF04190.13 RLN92842.1 - 2.6e-44 151.9 2.5 4.9e-36 124.8 1.3 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF410) TPR_14 PF13428.6 RLN92842.1 - 0.0066 17.2 13.2 0.028 15.2 0.5 4.7 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 RLN92842.1 - 0.029 14.7 3.4 2.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN92842.1 - 0.07 13.6 0.0 0.07 13.6 0.0 3.5 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN92842.1 - 0.45 10.7 0.0 0.45 10.7 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat BBIP10 PF14777.6 RLN92843.1 - 3.2e-20 71.5 0.2 4.2e-20 71.1 0.2 1.1 1 0 0 1 1 1 1 Cilia BBSome complex subunit 10 EXS PF03124.14 RLN92844.1 - 9.9e-06 25.1 0.8 9.9e-06 25.1 0.8 1.4 2 0 0 2 2 2 1 EXS family NUC153 PF08159.12 RLN92845.1 - 0.0015 18.3 0.2 0.0031 17.3 0.2 1.6 1 0 0 1 1 1 1 NUC153 domain DEPP PF15343.6 RLN92845.1 - 0.014 15.4 6.2 0.017 15.2 6.2 1.0 1 0 0 1 1 1 0 Decidual protein induced by progesterone family SR-25 PF10500.9 RLN92845.1 - 0.22 11.1 17.7 0.24 11.0 17.7 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Patched PF02460.18 RLN92846.1 - 9.5e-73 245.6 9.8 5.8e-70 236.4 7.9 2.9 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 RLN92846.1 - 1.1e-39 135.7 7.8 1.1e-39 135.7 7.8 3.5 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Ribosomal_S17 PF00366.20 RLN92847.1 - 4.1e-27 94.1 0.9 4.1e-27 94.1 0.9 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 eIF-1a PF01176.19 RLN92847.1 - 0.054 13.3 0.6 1.1 9.1 0.0 2.4 1 1 0 2 2 2 0 Translation initiation factor 1A / IF-1 RRM_1 PF00076.22 RLN92848.1 - 3e-30 103.8 0.1 2.2e-15 56.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN92848.1 - 4.5e-07 29.9 0.0 7.2e-05 22.8 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif MT-A70 PF05063.14 RLN92849.1 - 2.9e-34 118.5 0.3 4.4e-34 117.9 0.3 1.3 1 0 0 1 1 1 1 MT-A70 DUF1664 PF07889.12 RLN92850.1 - 0.0021 18.1 0.3 0.0021 18.1 0.3 5.0 2 2 4 6 6 6 3 Protein of unknown function (DUF1664) Sugar_tr PF00083.24 RLN92852.1 - 9.6e-106 354.3 20.5 1.1e-105 354.2 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN92852.1 - 3.2e-26 92.1 32.0 2e-19 69.7 3.1 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily Caps_synth_CapC PF14102.6 RLN92852.1 - 0.15 12.5 4.4 0.16 12.4 0.3 2.7 2 0 0 2 2 2 0 Capsule biosynthesis CapC MFS_2 PF13347.6 RLN92852.1 - 0.21 10.1 18.9 0.013 14.1 1.3 3.5 3 1 1 4 4 4 0 MFS/sugar transport protein Pkinase PF00069.25 RLN92853.1 - 2.5e-16 59.8 0.1 8.5e-12 45.0 0.0 3.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92853.1 - 3.9e-05 23.1 0.0 0.017 14.4 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase RRXRR PF14239.6 RLN92853.1 - 0.04 13.8 0.1 0.086 12.7 0.1 1.4 1 1 0 1 1 1 0 RRXRR protein Haspin_kinase PF12330.8 RLN92853.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pro_isomerase PF00160.21 RLN92854.1 - 2.7e-34 118.7 0.1 2.7e-20 73.2 0.0 2.6 1 1 1 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 RLN92854.1 - 1.3e-08 34.5 0.1 1.3e-08 34.5 0.1 2.2 2 0 0 2 2 2 1 Rtf2 RING-finger Arm PF00514.23 RLN92855.1 - 4e-14 52.1 17.8 0.0049 16.9 0.2 6.8 6 1 1 7 7 7 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN92855.1 - 4.2e-05 23.5 1.3 1.8 9.0 0.0 4.3 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 RLN92855.1 - 0.0002 21.7 16.7 0.011 16.1 0.8 4.5 2 1 4 6 6 6 4 HEAT repeats Arm_2 PF04826.13 RLN92855.1 - 0.00034 20.2 0.0 0.27 10.7 0.0 2.4 2 0 0 2 2 2 2 Armadillo-like HEAT_EZ PF13513.6 RLN92855.1 - 0.0018 18.8 22.4 0.0035 17.8 0.9 5.0 5 1 0 5 5 5 2 HEAT-like repeat Atx10homo_assoc PF09759.9 RLN92855.1 - 0.013 15.5 0.0 0.49 10.4 0.1 2.4 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Aa_trans PF01490.18 RLN92858.1 - 1.9e-33 115.8 13.3 8.9e-21 74.1 0.8 2.2 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Keratin_assoc PF09775.9 RLN92858.1 - 0.23 11.1 4.1 0.82 9.3 4.1 1.9 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 DUF1804 PF08822.11 RLN92859.1 - 0.0039 17.2 3.3 5.7 6.9 0.0 3.3 2 1 1 3 3 3 3 Protein of unknown function (DUF1804) Med29 PF11568.8 RLN92859.1 - 0.012 15.9 0.1 4.7 7.4 0.0 3.1 3 0 0 3 3 3 0 Mediator complex subunit 29 GlcNAc PF11397.8 RLN92860.1 - 1.4e-47 162.9 1.6 1.7e-38 133.0 0.1 3.1 2 1 1 3 3 3 2 Glycosyltransferase (GlcNAc) BLM10_mid PF16507.5 RLN92861.1 - 1.9e-56 191.8 0.0 4e-56 190.8 0.0 1.5 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region Cnd1 PF12717.7 RLN92861.1 - 0.0076 16.3 0.3 0.062 13.3 0.0 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 RLN92861.1 - 0.14 12.2 3.5 1 9.5 0.1 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat ATG7_N PF16420.5 RLN92862.1 - 8.1e-57 193.1 0.0 3.5e-47 161.5 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 RLN92862.1 - 2.1e-20 73.1 0.0 3.3e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 RLN92862.1 - 0.088 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Tox-REase-7 PF15649.6 RLN92862.1 - 0.19 12.0 0.1 0.54 10.6 0.0 1.7 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 7 Voltage_CLC PF00654.20 RLN92863.1 - 6.2e-82 275.7 29.8 6.2e-82 275.7 29.8 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel ISN1 PF06437.11 RLN92863.1 - 0.17 10.8 0.0 0.25 10.2 0.0 1.1 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase TAT_signal PF10518.9 RLN92863.1 - 4.2 7.4 9.2 0.36 10.7 2.9 2.7 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence GFO_IDH_MocA PF01408.22 RLN92864.1 - 8.4e-27 94.4 1.4 3.9e-12 47.0 0.1 2.5 2 0 0 2 2 2 2 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 RLN92864.1 - 9.7e-09 35.3 0.1 0.002 18.2 0.0 2.7 3 0 0 3 3 3 2 Oxidoreductase family, C-terminal alpha/beta domain PuR_N PF09182.10 RLN92864.1 - 0.049 13.6 0.5 2.4 8.1 0.0 3.3 4 0 0 4 4 4 0 Bacterial purine repressor, N-terminal FYVE PF01363.21 RLN92865.1 - 3.1e-05 24.0 10.6 7.3e-05 22.8 10.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN92865.1 - 0.0019 18.4 13.9 0.0076 16.5 13.9 2.1 1 1 0 1 1 1 1 FYVE-type zinc finger C1_1 PF00130.22 RLN92865.1 - 0.74 9.8 13.7 0.43 10.5 7.7 2.8 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Peptidase_S21 PF00716.17 RLN92866.1 - 0.78 9.4 10.8 0.96 9.1 10.8 1.1 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) RR_TM4-6 PF06459.12 RLN92866.1 - 5.3 6.8 8.9 6.7 6.5 8.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF572 PF04502.13 RLN92866.1 - 8 6.0 7.7 8.9 5.8 7.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) FYVE PF01363.21 RLN92867.1 - 4.7e-08 33.0 9.7 4.7e-08 33.0 9.7 2.0 2 0 0 2 2 2 1 FYVE zinc finger GAF_2 PF13185.6 RLN92867.1 - 9.2e-05 22.8 0.1 0.00031 21.0 0.1 1.9 1 0 0 1 1 1 1 GAF domain Siva PF05458.12 RLN92867.1 - 0.12 12.0 4.2 0.33 10.6 4.2 1.7 1 0 0 1 1 1 0 Cd27 binding protein (Siva) FYVE_2 PF02318.16 RLN92867.1 - 2.1 8.6 10.6 6 7.1 10.6 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger zf-piccolo PF05715.13 RLN92867.1 - 4.3 7.5 8.6 16 5.7 8.6 1.9 1 1 0 1 1 1 0 Piccolo Zn-finger zf-B_box PF00643.24 RLN92867.1 - 6.3 7.0 9.1 1 9.5 4.9 1.8 2 0 0 2 2 2 0 B-box zinc finger Retrotrans_gag PF03732.17 RLN92868.1 - 0.023 15.0 0.2 0.047 14.0 0.2 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein Alpha_kinase PF02816.18 RLN92869.1 - 4e-51 173.8 0.0 5.4e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family SHOCT PF09851.9 RLN92869.1 - 0.0035 17.0 0.0 0.0077 15.9 0.0 1.6 1 0 0 1 1 1 1 Short C-terminal domain Ribosomal_60s PF00428.19 RLN92869.1 - 0.16 12.6 5.7 0.3 11.7 5.7 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4746 PF15928.5 RLN92869.1 - 0.84 9.0 4.4 1.4 8.3 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) E_raikovi_mat PF06360.11 RLN92870.1 - 0.061 13.8 0.9 0.12 12.8 0.2 1.9 2 0 0 2 2 2 0 Euplotes raikovi mating pheromone DHC_N1 PF08385.12 RLN92871.1 - 1.3e-180 601.8 0.0 1.3e-180 601.8 0.0 3.1 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 RLN92871.1 - 2.3e-137 457.4 1.3 7.1e-75 252.0 0.0 3.1 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN92871.1 - 2.6e-102 342.9 0.0 2.6e-102 342.9 0.0 5.6 6 2 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RLN92871.1 - 1.5e-91 306.3 0.0 1.2e-89 300.0 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RLN92871.1 - 1.1e-78 263.4 0.7 2.5e-77 258.9 0.1 2.7 2 1 0 2 2 2 1 ATP-binding dynein motor region Dynein_C PF18199.1 RLN92871.1 - 8e-76 255.2 0.0 4e-73 246.3 0.0 4.0 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain MT PF12777.7 RLN92871.1 - 1.7e-74 251.0 13.8 3e-74 250.1 13.8 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 RLN92871.1 - 7.1e-66 221.2 0.0 9.6e-59 197.9 0.0 3.9 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RLN92871.1 - 1e-36 126.2 0.0 2.9e-36 124.8 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RLN92871.1 - 2.5e-36 124.4 0.0 1.4e-32 112.2 0.0 3.8 2 1 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 RLN92871.1 - 8.1e-25 87.4 0.0 2.2e-09 37.4 0.0 5.2 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 RLN92871.1 - 1e-23 83.4 0.1 4.9e-23 81.2 0.1 2.3 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 RLN92871.1 - 2.5e-18 66.4 0.0 8.4e-18 64.7 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 RLN92871.1 - 1.5e-10 41.7 0.0 0.0045 17.4 0.0 5.8 5 0 0 5 5 4 2 AAA ATPase domain AAA PF00004.29 RLN92871.1 - 1.3e-07 32.1 0.5 0.53 10.7 0.0 5.6 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN92871.1 - 6.2e-07 29.8 0.0 1.1 9.6 0.0 5.2 3 1 1 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 RLN92871.1 - 2.2e-05 24.4 0.0 0.051 13.5 0.0 3.2 3 0 0 3 3 3 1 RsgA GTPase RNA_helicase PF00910.22 RLN92871.1 - 6.4e-05 23.3 0.0 9.4 6.7 0.0 4.7 4 0 0 4 4 4 0 RNA helicase AAA_18 PF13238.6 RLN92871.1 - 8e-05 23.2 0.1 2.5 8.6 0.0 4.6 4 0 0 4 4 4 1 AAA domain TsaE PF02367.17 RLN92871.1 - 0.00025 21.0 0.3 20 5.2 0.0 4.7 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 RLN92871.1 - 0.00031 20.4 0.1 4.9 7.0 0.0 3.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain DUF815 PF05673.13 RLN92871.1 - 0.00044 19.5 0.1 0.2 10.8 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 RLN92871.1 - 0.0006 20.3 0.0 3.4 8.2 0.0 3.4 2 0 0 2 2 2 2 ABC transporter AAA_33 PF13671.6 RLN92871.1 - 0.00075 19.7 2.3 0.31 11.2 0.0 4.4 5 0 0 5 5 3 1 AAA domain AAA_25 PF13481.6 RLN92871.1 - 0.0078 15.8 1.0 7.3 6.1 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 RLN92871.1 - 0.013 15.6 0.0 1 9.4 0.0 3.8 4 0 0 4 4 4 0 AAA domain Mg_chelatase PF01078.21 RLN92871.1 - 0.018 14.4 0.2 1.9 7.8 0.0 3.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 RLN92871.1 - 0.037 13.4 0.0 2 7.8 0.0 3.1 3 0 0 3 3 3 0 Bacterial TniB protein Roc PF08477.13 RLN92871.1 - 0.056 13.7 0.0 1.9 8.8 0.0 3.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 RLN92871.1 - 0.065 13.5 0.1 59 3.9 0.0 3.7 3 0 0 3 3 3 0 AAA domain Guanylate_kin PF00625.21 RLN92871.1 - 0.076 12.7 0.0 3.8 7.2 0.0 2.8 2 0 0 2 2 2 0 Guanylate kinase Zeta_toxin PF06414.12 RLN92871.1 - 0.087 12.1 0.1 2.5 7.4 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin NACHT PF05729.12 RLN92871.1 - 0.13 12.1 0.2 21 5.0 0.0 3.2 3 0 0 3 3 2 0 NACHT domain Sod_Cu PF00080.20 RLN92872.1 - 4.5e-34 117.7 3.3 5.5e-34 117.4 3.3 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) MIP PF00230.20 RLN92874.1 - 1.9e-55 188.1 7.8 2.3e-55 187.8 7.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein Phage_holin_8 PF16931.5 RLN92874.1 - 0.098 12.6 0.0 0.098 12.6 0.0 2.0 3 0 0 3 3 3 0 Putative phage holin CPP1-like PF11833.8 RLN92874.1 - 0.35 10.5 0.9 0.9 9.2 0.0 1.9 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF4064 PF13273.6 RLN92874.1 - 1.5 9.1 5.8 0.48 10.7 0.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Polysacc_synt_C PF14667.6 RLN92874.1 - 1.7 8.7 12.4 2.5 8.1 0.1 3.2 2 1 1 3 3 3 0 Polysaccharide biosynthesis C-terminal domain ABC_membrane PF00664.23 RLN92875.1 - 2.1e-100 335.9 31.9 3.4e-50 171.2 6.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN92875.1 - 1.8e-35 122.4 0.1 3.2e-35 121.6 0.1 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN92875.1 - 1.6e-06 27.7 0.2 1.6e-05 24.5 0.0 1.9 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RLN92875.1 - 0.00097 19.4 0.3 0.0056 17.0 0.3 2.1 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 RLN92875.1 - 0.001 17.9 0.9 0.0019 17.1 0.2 1.7 2 0 0 2 2 2 1 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 RLN92875.1 - 0.0035 17.3 0.0 0.0079 16.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_5 PF07728.14 RLN92875.1 - 0.0061 16.6 0.2 1.7 8.6 0.1 2.8 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 RLN92875.1 - 0.011 15.4 0.0 0.044 13.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain MtrB PF05440.12 RLN92875.1 - 0.031 14.7 1.1 22 5.5 0.0 4.0 4 0 0 4 4 3 0 Tetrahydromethanopterin S-methyltransferase subunit B AAA_16 PF13191.6 RLN92875.1 - 0.032 14.6 0.5 0.11 12.9 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain MoaE PF02391.17 RLN92875.1 - 0.037 14.3 0.3 0.21 11.9 0.3 2.3 1 0 0 1 1 1 0 MoaE protein DEAD PF00270.29 RLN92875.1 - 0.061 13.1 0.4 0.22 11.3 0.4 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_25 PF13481.6 RLN92875.1 - 0.074 12.6 0.1 8.4 5.9 0.1 2.6 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 RLN92875.1 - 0.17 11.5 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 RLN92876.1 - 0.24 11.5 2.4 12 6.1 0.3 2.5 1 1 1 2 2 2 0 AAA domain zf-4CXXC_R1 PF10497.9 RLN92876.1 - 1 9.6 10.7 0.72 10.1 7.4 2.2 1 1 1 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-rbx1 PF12678.7 RLN92877.1 - 6.2e-09 36.0 6.9 9.6e-09 35.4 6.9 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain Zip PF02535.22 RLN92878.1 - 5.6e-40 137.6 13.3 6.5e-40 137.4 13.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Phage_holin_3_3 PF16083.5 RLN92878.1 - 1.4 9.1 9.3 17 5.6 0.2 4.0 3 1 1 4 4 4 0 LydA holin phage, holin superfamily III DUF5578 PF17741.1 RLN92879.1 - 2.9e-08 33.5 0.0 0.00039 19.9 0.0 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5578) DUF913 PF06025.12 RLN92879.1 - 0.00026 20.1 0.1 0.00047 19.2 0.1 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) NleF_casp_inhib PF16809.5 RLN92879.1 - 0.094 12.6 0.8 0.68 9.8 0.3 2.2 2 0 0 2 2 2 0 NleF caspase inhibitor Connexin PF00029.19 RLN92879.1 - 1.1 9.0 5.9 5 6.8 0.0 2.2 2 0 0 2 2 2 0 Connexin GYF PF02213.16 RLN92880.1 - 6.1e-16 57.8 0.2 1.2e-15 56.9 0.2 1.5 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 RLN92880.1 - 0.00032 20.5 0.1 0.0012 18.6 0.1 2.1 1 0 0 1 1 1 1 GYF domain 2 Syntaxin_2 PF14523.6 RLN92881.1 - 0.011 16.1 2.1 0.011 16.1 2.1 1.7 2 0 0 2 2 1 0 Syntaxin-like protein Bap31_Bap29_C PF18035.1 RLN92881.1 - 0.069 13.2 0.5 0.18 11.8 0.2 1.9 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain UPF0449 PF15136.6 RLN92881.1 - 0.076 13.5 1.2 0.076 13.5 1.2 2.6 1 1 2 3 3 3 0 Uncharacterised protein family UPF0449 Nup88 PF10168.9 RLN92881.1 - 0.092 10.6 3.7 0.12 10.2 3.7 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF4515 PF14988.6 RLN92881.1 - 0.1 12.4 6.5 0.19 11.6 6.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) TPR_MLP1_2 PF07926.12 RLN92881.1 - 0.1 12.6 9.7 0.22 11.6 9.7 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 RLN92881.1 - 0.1 11.4 7.7 0.15 10.9 7.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.8 RLN92881.1 - 0.11 9.9 5.9 0.13 9.7 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GAS PF13851.6 RLN92881.1 - 0.11 11.8 7.9 0.19 11.1 7.9 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SHE3 PF17078.5 RLN92881.1 - 0.12 12.1 5.7 0.18 11.5 5.7 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 V_ATPase_I PF01496.19 RLN92881.1 - 0.12 10.2 1.6 0.11 10.4 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family JIP_LZII PF16471.5 RLN92881.1 - 0.13 12.4 6.7 0.4 10.9 6.7 1.8 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II HAUS-augmin3 PF14932.6 RLN92881.1 - 0.14 11.8 6.0 0.19 11.3 6.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ING PF12998.7 RLN92881.1 - 0.21 12.2 3.4 0.57 10.8 0.4 2.2 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding SKA2 PF16740.5 RLN92881.1 - 0.27 11.0 6.7 0.93 9.3 3.8 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 OmpH PF03938.14 RLN92881.1 - 0.27 11.5 5.1 1.5 9.2 5.1 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TSC22 PF01166.18 RLN92881.1 - 0.32 11.3 6.9 1.5 9.2 1.1 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family bZIP_1 PF00170.21 RLN92881.1 - 0.36 11.0 7.1 5.9 7.1 2.2 2.5 1 1 1 2 2 2 0 bZIP transcription factor ADIP PF11559.8 RLN92881.1 - 0.51 10.4 8.6 0.9 9.6 8.6 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FapA PF03961.13 RLN92881.1 - 0.55 8.8 3.2 0.69 8.5 3.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A CCDC-167 PF15188.6 RLN92881.1 - 0.56 10.6 6.0 0.91 9.9 6.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 CorA PF01544.18 RLN92881.1 - 0.58 9.4 5.3 0.94 8.7 5.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HAP1_N PF04849.13 RLN92881.1 - 0.63 9.2 10.7 0.92 8.7 10.7 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region HIP1_clath_bdg PF16515.5 RLN92881.1 - 0.77 10.4 10.9 1.6 9.4 10.9 1.6 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CENP-F_leu_zip PF10473.9 RLN92881.1 - 0.82 9.7 12.2 8.2 6.5 12.2 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD_2 PF14197.6 RLN92881.1 - 1.1 9.4 11.6 1.4 9.1 3.9 2.6 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 FlaC_arch PF05377.11 RLN92881.1 - 1.3 9.4 4.7 3.8 8.0 0.5 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) HALZ PF02183.18 RLN92881.1 - 1.4 9.2 5.2 12 6.2 0.5 2.7 2 1 0 2 2 2 0 Homeobox associated leucine zipper Spc24 PF08286.11 RLN92881.1 - 1.6 9.0 12.1 4.4 7.6 3.8 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 CENP-H PF05837.12 RLN92881.1 - 2 8.8 10.2 4.2 7.8 10.2 1.7 1 1 0 1 1 1 0 Centromere protein H (CENP-H) COG2 PF06148.11 RLN92881.1 - 2.1 8.4 6.8 0.69 10.0 1.1 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cnn_1N PF07989.11 RLN92881.1 - 2.3 8.5 7.1 6.7 7.0 1.0 2.4 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 RLN92881.1 - 2.6 8.5 12.7 2 8.9 4.0 2.3 1 1 1 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 RLN92881.1 - 2.8 7.8 6.9 2.4 8.0 2.7 2.3 1 1 1 2 2 2 0 Septum formation initiator bZIP_2 PF07716.15 RLN92881.1 - 2.8 8.1 8.9 11 6.2 3.4 2.6 2 0 0 2 2 2 0 Basic region leucine zipper HalX PF08663.10 RLN92881.1 - 3.5 8.0 8.5 1.3 9.4 3.7 2.2 1 1 1 2 2 2 0 HalX domain DUF3450 PF11932.8 RLN92881.1 - 3.8 6.7 10.8 2.7 7.2 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 RLN92881.1 - 4 8.0 12.5 9.6 6.7 3.9 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region YabA PF06156.13 RLN92881.1 - 6.9 7.4 8.3 1.3e+02 3.3 8.3 2.3 1 1 0 1 1 1 0 Initiation control protein YabA GIT1_C PF12205.8 RLN92881.1 - 8.7 6.5 7.9 28 4.9 6.7 2.3 2 1 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term Med11 PF10280.9 RLN92882.1 - 2.6e-11 44.1 0.3 3.6e-11 43.7 0.3 1.2 1 0 0 1 1 1 1 Mediator complex protein GARP PF16731.5 RLN92882.1 - 0.0075 16.0 1.5 0.0099 15.6 1.5 1.1 1 0 0 1 1 1 1 Glutamic acid/alanine-rich protein of Trypanosoma APG17 PF04108.12 RLN92882.1 - 0.011 14.9 0.7 0.014 14.6 0.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 Hemerythrin PF01814.23 RLN92882.1 - 0.016 15.8 1.4 0.084 13.5 0.6 2.0 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Mating_N PF12731.7 RLN92882.1 - 0.023 14.8 1.4 1.4 9.0 0.8 2.5 2 1 0 2 2 2 0 Mating-type protein beta 1 TisB_toxin PF13939.6 RLN92882.1 - 0.18 11.6 0.2 0.3 10.9 0.2 1.4 1 0 0 1 1 1 0 Toxin TisB, type I toxin-antitoxin system WW PF00397.26 RLN92883.1 - 3.9e-10 39.6 0.0 6.8e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 WW domain CFAP91 PF14738.6 RLN92884.1 - 8.9e-52 175.2 6.4 8.9e-52 175.2 6.4 2.2 3 1 0 3 3 3 1 Cilia- and flagella-associated protein 91 Amino_oxidase PF01593.24 RLN92884.1 - 6.9e-26 91.5 0.2 1.7e-25 90.2 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DUF4520 PF15016.6 RLN92884.1 - 0.00028 20.9 0.5 0.039 14.0 0.2 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4520) Ax_dynein_light PF10211.9 RLN92885.1 - 3.1e-70 235.9 0.4 3.6e-70 235.7 0.4 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain Nup54 PF13874.6 RLN92885.1 - 0.063 13.4 1.6 0.11 12.6 1.6 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DivIC PF04977.15 RLN92885.1 - 0.55 10.0 3.2 1 9.2 2.8 1.7 1 1 0 1 1 1 0 Septum formation initiator Pedibin PF08182.11 RLN92885.1 - 1.3 8.8 7.5 0.18 11.6 0.5 2.6 2 0 0 2 2 2 0 Pedibin/Hym-346 family Ras PF00071.22 RLN92887.1 - 3.6e-07 29.9 0.0 0.00032 20.3 0.0 2.3 1 1 1 2 2 2 2 Ras family Roc PF08477.13 RLN92887.1 - 0.0012 19.1 0.0 0.068 13.4 0.0 2.5 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 RLN92887.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RTT107_BRCT_5 PF16770.5 RLN92888.1 - 7.5e-06 25.8 0.0 2.1e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 RLN92888.1 - 0.0084 16.5 0.0 0.24 11.8 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF4140 PF13600.6 RLN92888.1 - 0.012 16.0 2.2 0.041 14.3 0.6 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) MTS PF05175.14 RLN92888.1 - 0.14 11.7 0.1 0.33 10.5 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase small domain SRP-alpha_N PF04086.13 RLN92888.1 - 9.5 6.0 16.5 17 5.2 16.5 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal adh_short PF00106.25 RLN92890.1 - 1.2e-31 109.7 0.1 1.5e-27 96.3 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN92890.1 - 5.4e-19 68.7 0.1 1.3e-18 67.4 0.1 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN92890.1 - 3.4e-08 33.6 0.1 5.5e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Pyr_redox_3 PF13738.6 RLN92890.1 - 0.00036 19.9 0.0 0.00049 19.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 RLN92890.1 - 0.0083 15.6 0.1 0.012 15.1 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 RLN92890.1 - 0.023 15.0 0.1 0.043 14.1 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 RLN92890.1 - 0.089 12.7 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LRR_8 PF13855.6 RLN92891.1 - 2.2e-40 136.2 57.5 1.6e-12 47.0 3.2 10.2 4 3 8 12 12 12 12 Leucine rich repeat LRR_4 PF12799.7 RLN92891.1 - 3e-28 97.4 54.4 4.6e-05 23.7 1.3 11.8 4 3 8 14 14 14 13 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN92891.1 - 1.5e-08 34.3 23.0 0.0019 17.7 0.6 5.7 3 2 2 6 6 6 5 Leucine-rich repeat LRR_1 PF00560.33 RLN92891.1 - 9.7e-07 28.5 41.0 0.74 10.6 0.4 13.2 14 4 0 14 14 14 3 Leucine Rich Repeat LRR_6 PF13516.6 RLN92891.1 - 0.0032 17.4 39.3 0.91 9.7 1.1 11.6 12 0 0 12 12 12 3 Leucine Rich repeat LRR_5 PF13306.6 RLN92891.1 - 0.016 15.2 0.1 0.22 11.5 0.0 2.4 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) RsmF_methylt_CI PF17126.5 RLN92891.1 - 0.084 12.9 1.2 22 5.2 0.0 4.6 4 1 2 6 6 6 0 RsmF rRNA methyltransferase first C-terminal domain LRR_3 PF07725.12 RLN92891.1 - 0.092 12.6 1.8 25 4.9 0.1 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat Cep57_MT_bd PF06657.13 RLN92891.1 - 0.14 12.6 2.3 0.2 12.1 0.2 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 rRNA_proc-arch PF13234.6 RLN92891.1 - 0.18 11.7 1.8 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 rRNA-processing arch domain LRR_8 PF13855.6 RLN92892.1 - 9.4e-30 102.2 39.9 4.1e-09 36.1 0.2 8.8 7 4 2 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 RLN92892.1 - 5.3e-27 93.4 34.0 5.9e-05 23.4 0.2 9.5 7 3 2 10 10 10 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN92892.1 - 2.4e-09 36.9 11.6 0.0013 18.3 0.1 5.1 2 2 3 6 6 6 2 Leucine-rich repeat LRR_1 PF00560.33 RLN92892.1 - 8.9e-07 28.6 28.8 2.8 8.8 0.1 12.4 13 2 0 13 13 13 2 Leucine Rich Repeat LRR_6 PF13516.6 RLN92892.1 - 1.9e-05 24.3 26.3 2.2 8.5 0.2 10.0 10 0 0 10 10 10 3 Leucine Rich repeat Methyltransf_PK PF05891.12 RLN92892.1 - 0.019 14.5 0.2 7 6.1 0.1 2.3 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase Glycophorin_A PF01102.18 RLN92893.1 - 0.023 14.9 0.2 0.023 14.9 0.2 2.0 2 0 0 2 2 2 0 Glycophorin A DUF5305 PF17231.2 RLN92893.1 - 0.079 12.4 0.3 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5305) RTA1 PF04479.13 RLN92893.1 - 0.099 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 RTA1 like protein DUF1180 PF06679.12 RLN92893.1 - 0.29 11.6 3.5 0.45 10.9 2.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) Podoplanin PF05808.11 RLN92893.1 - 0.76 9.9 9.8 0.095 12.8 5.1 1.7 1 1 1 2 2 2 0 Podoplanin OrfB_IS605 PF01385.19 RLN92895.1 - 2.6e-05 24.4 0.0 5.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Probable transposase Mlh1_C PF16413.5 RLN92898.1 - 1.5e-68 231.2 3.9 8.7e-68 228.6 0.3 2.9 2 1 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus Peptidase_M24 PF00557.24 RLN92898.1 - 6.7e-45 153.4 0.0 1.2e-44 152.5 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 RLN92898.1 - 8.4e-39 132.1 0.0 1.8e-38 131.1 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain HATPase_c_3 PF13589.6 RLN92898.1 - 3.2e-12 46.4 0.0 7.4e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 RLN92898.1 - 1.6e-07 31.8 0.0 3.7e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MycE_N PF17843.1 RLN92898.1 - 0.16 12.5 0.8 0.39 11.2 0.8 1.7 1 0 0 1 1 1 0 MycE methyltransferase N-terminal FAM183 PF14886.6 RLN92898.1 - 0.22 12.3 1.1 0.76 10.5 1.1 1.9 1 1 0 1 1 1 0 FAM183A and FAM183B related GET2 PF08690.10 RLN92898.1 - 3.6 7.2 13.2 6.1 6.4 13.2 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Ribosomal_S8e PF01201.22 RLN92899.1 - 2.6e-49 166.9 6.5 3.5e-47 160.0 6.5 2.1 1 1 0 1 1 1 1 Ribosomal protein S8e Gti1_Pac2 PF09729.9 RLN92899.1 - 0.16 12.1 4.3 0.29 11.2 4.3 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family BT1 PF03092.16 RLN92900.1 - 4.6e-16 58.1 16.5 5.4e-10 38.1 0.6 3.5 3 1 1 4 4 4 3 BT1 family PUCC PF03209.15 RLN92900.1 - 0.00024 20.2 0.2 0.00024 20.2 0.2 2.6 3 0 0 3 3 3 1 PUCC protein DUF4131 PF13567.6 RLN92900.1 - 1.5 8.4 0.0 1.5 8.4 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) Thiolase_N PF00108.23 RLN92901.1 - 2.5e-69 233.6 0.3 6.7e-69 232.1 0.3 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RLN92901.1 - 6.8e-35 119.4 0.0 2.2e-34 117.8 0.0 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain SpoVAD PF07451.11 RLN92901.1 - 8.9e-07 27.9 0.1 5.1e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.26 RLN92901.1 - 0.00057 19.5 2.3 0.00057 19.5 2.3 2.8 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 RLN92901.1 - 0.053 13.4 0.5 2 8.3 0.2 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FYVE PF01363.21 RLN92902.1 - 0.0045 17.1 8.1 0.0082 16.3 8.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger Bd3614-deam PF14439.6 RLN92902.1 - 0.17 12.0 0.6 0.4 10.7 0.6 1.7 1 1 0 1 1 1 0 Bd3614-like deaminase FYVE_2 PF02318.16 RLN92902.1 - 0.41 10.9 3.5 1 9.6 3.5 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger Aminotran_1_2 PF00155.21 RLN92903.1 - 8.7e-63 212.7 0.0 1e-62 212.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 RLN92903.1 - 0.0019 17.6 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 RLN92903.1 - 0.067 11.9 0.0 0.32 9.7 0.0 1.8 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain LOH1CR12 PF10158.9 RLN92903.1 - 0.24 11.4 0.7 1.4 9.0 0.4 2.1 2 0 0 2 2 2 0 Tumour suppressor protein Pkinase PF00069.25 RLN92904.1 - 2.8e-57 194.1 0.0 8.1e-57 192.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92904.1 - 1.9e-27 96.2 0.0 4.5e-25 88.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase PAS PF00989.25 RLN92904.1 - 8.2e-10 38.7 0.0 1.7e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 RLN92904.1 - 1.4e-05 25.3 0.0 3.6e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 RLN92904.1 - 3.8e-05 23.9 0.0 8.6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 RLN92904.1 - 0.00028 20.8 0.0 0.00077 19.4 0.0 1.7 1 0 0 1 1 1 1 PAS domain Kdo PF06293.14 RLN92904.1 - 0.0023 17.3 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN92904.1 - 0.016 15.1 0.1 0.036 14.0 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Rz1 PF06085.11 RLN92904.1 - 0.027 14.2 0.1 1.6 8.5 0.0 2.8 2 0 0 2 2 2 0 Lipoprotein Rz1 precursor Aminotran_1_2 PF00155.21 RLN92905.1 - 3e-55 187.9 0.0 4.2e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II PDT PF00800.18 RLN92905.1 - 1.3e-11 44.6 0.0 8.3e-11 42.0 0.0 2.2 2 0 0 2 2 2 1 Prephenate dehydratase ACT PF01842.25 RLN92905.1 - 0.011 15.4 0.0 0.14 12.0 0.0 2.9 2 1 0 2 2 2 0 ACT domain Erythrovirus_X PF06795.11 RLN92905.1 - 0.027 14.7 0.2 0.56 10.5 0.0 2.8 3 0 0 3 3 3 0 Erythrovirus X protein BLACT_WH PF17778.1 RLN92906.1 - 0.062 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain Vps23_core PF09454.10 RLN92906.1 - 0.088 12.8 0.3 0.2 11.6 0.1 1.6 2 0 0 2 2 2 0 Vps23 core domain Biotin_lipoyl_2 PF13533.6 RLN92906.1 - 0.21 11.5 0.2 0.21 11.5 0.2 1.8 2 0 0 2 2 2 0 Biotin-lipoyl like Cadherin_3 PF16184.5 RLN92907.1 - 5.4e-09 36.0 3.8 0.0086 16.1 0.0 6.6 7 0 0 7 7 7 3 Cadherin-like Cadherin_4 PF17803.1 RLN92907.1 - 1.1e-05 25.9 24.9 0.2 12.3 0.5 10.1 10 0 0 10 10 10 3 Bacterial cadherin-like domain Cadherin_5 PF17892.1 RLN92907.1 - 0.014 15.3 0.1 29 4.7 0.0 4.6 3 0 0 3 3 3 0 Cadherin-like domain Big_9 PF17963.1 RLN92907.1 - 0.15 12.8 32.1 4.6 8.0 0.2 13.1 15 2 1 16 16 16 0 Bacterial Ig domain FYVE PF01363.21 RLN92908.1 - 1.6e-13 50.5 12.9 3.2e-13 49.6 12.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 RLN92908.1 - 1.8e-05 24.3 0.1 4.4e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 START domain FYVE_2 PF02318.16 RLN92908.1 - 0.25 11.5 8.2 0.62 10.3 8.2 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger DivIC PF04977.15 RLN92909.1 - 0.0033 17.2 3.3 0.0033 17.2 3.3 7.1 4 2 2 7 7 7 1 Septum formation initiator GNAT_acetyltr_2 PF13718.6 RLN92910.1 - 3.1e-98 327.7 0.2 1.8e-97 325.2 0.0 2.4 2 0 0 2 2 2 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 RLN92910.1 - 2.6e-68 230.3 2.0 2.6e-68 230.3 2.0 2.0 2 0 0 2 2 2 1 Possible tRNA binding domain Helicase_RecD PF05127.14 RLN92910.1 - 3.5e-62 209.4 0.1 1.1e-61 207.8 0.1 1.9 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.11 RLN92910.1 - 2.3e-33 114.0 0.1 5.5e-33 112.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 RLN92910.1 - 0.0015 18.8 0.0 0.29 11.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain CBS PF00571.28 RLN92910.1 - 0.76 10.3 5.2 96 3.5 5.2 2.9 1 1 0 1 1 1 0 CBS domain DUF21 PF01595.20 RLN92911.1 - 1.5e-12 47.6 1.7 1.8e-12 47.3 1.0 1.4 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain DUF3273 PF11677.8 RLN92911.1 - 0.066 12.5 0.2 0.094 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3273) Gp45_2 PF17470.2 RLN92912.1 - 0.061 13.3 0.0 0.082 12.9 0.0 1.2 1 0 0 1 1 1 0 Phage gene product 45.2 Peroxin-22 PF12827.7 RLN92914.1 - 0.013 15.4 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family Ank_2 PF12796.7 RLN92917.1 - 2e-53 178.9 16.2 1.4e-07 32.0 0.0 7.1 1 1 10 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN92917.1 - 3.4e-40 135.9 25.1 0.00016 22.2 0.3 10.6 5 5 5 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN92917.1 - 2.9e-38 129.4 24.2 0.022 15.1 0.0 14.4 2 1 12 15 15 15 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN92917.1 - 1.8e-17 61.6 10.0 20 6.2 0.0 14.0 15 1 1 16 16 16 2 Ankyrin repeat DUF5049 PF16468.5 RLN92917.1 - 4.3e-07 29.7 0.0 58 3.7 0.0 8.5 7 2 3 10 10 10 0 Domain of unknown function (DUF5049) Ank PF00023.30 RLN92917.1 - 2.4e-05 24.6 3.4 1.1e+02 3.6 0.0 8.8 8 4 3 11 11 11 0 Ankyrin repeat VHL_C PF17211.3 RLN92917.1 - 0.0033 17.4 0.4 49 4.1 0.0 6.1 8 0 0 8 8 8 0 VHL box domain Cpn60_TCP1 PF00118.24 RLN92919.1 - 5.6e-14 51.6 0.0 1.1e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family TRAPP PF04051.16 RLN92920.1 - 2.1e-37 128.0 0.0 2.7e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Asp_Arg_Hydrox PF05118.15 RLN92921.1 - 1.1e-38 132.6 0.0 2.2e-38 131.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Methyltransf_11 PF08241.12 RLN92921.1 - 4.8e-16 59.2 0.0 9.1e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN92921.1 - 3.3e-14 53.0 0.0 5.8e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN92921.1 - 3.3e-13 50.1 0.0 7.2e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN92921.1 - 2.2e-11 44.4 0.0 4.4e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN92921.1 - 2.5e-10 40.4 0.0 4.3e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 RLN92921.1 - 5.1e-06 26.5 0.0 0.00042 20.2 0.0 2.2 2 0 0 2 2 2 1 Hypothetical methyltransferase MTS PF05175.14 RLN92921.1 - 6.8e-06 25.7 0.0 1.4e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 RLN92921.1 - 2.2e-05 23.9 0.0 3.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 RLN92921.1 - 0.0058 16.1 0.0 0.25 10.8 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase DUF2764 PF10962.8 RLN92921.1 - 0.049 13.1 0.3 0.091 12.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) MetW PF07021.12 RLN92921.1 - 0.051 13.2 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Pox_MCEL PF03291.16 RLN92921.1 - 0.2 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme Cupin_2 PF07883.11 RLN92921.1 - 1.6 8.5 4.1 1.9 8.3 0.1 2.8 3 0 0 3 3 3 0 Cupin domain Ank_4 PF13637.6 RLN92923.1 - 6.2e-50 167.0 32.0 2.9e-06 27.7 0.2 12.1 6 4 7 13 13 13 13 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN92923.1 - 4.6e-45 152.1 23.3 7.5e-09 36.1 0.2 7.9 2 1 8 10 10 10 9 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN92923.1 - 1.1e-40 137.1 34.3 0.00088 19.5 0.3 17.2 2 1 16 18 18 18 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN92923.1 - 2.2e-23 79.8 15.2 2.3 9.1 0.0 16.6 16 2 2 18 18 18 5 Ankyrin repeat DUF5049 PF16468.5 RLN92923.1 - 1.3e-07 31.4 0.0 16 5.5 0.0 9.0 6 3 4 10 10 10 1 Domain of unknown function (DUF5049) Ank PF00023.30 RLN92923.1 - 3.7e-07 30.3 12.8 48 4.6 0.3 11.3 7 3 3 10 10 10 0 Ankyrin repeat CNOT1_HEAT PF16418.5 RLN92923.1 - 0.12 12.5 0.8 32 4.6 0.0 4.7 5 2 0 5 5 5 0 CCR4-NOT transcription complex subunit 1 HEAT repeat PASTA PF03793.19 RLN92924.1 - 0.054 13.4 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 PASTA domain P5-ATPase PF12409.8 RLN92924.1 - 0.094 12.8 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 P5-type ATPase cation transporter PI3K_1B_p101 PF10486.9 RLN92924.1 - 0.19 9.5 0.0 0.27 9.0 0.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Myb_DNA-binding PF00249.31 RLN92925.1 - 3.8e-05 23.8 0.0 5.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain TMEM247 PF15444.6 RLN92925.1 - 0.068 13.2 0.4 0.089 12.8 0.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 FAD-oxidase_C PF02913.19 RLN92926.1 - 3.8e-100 334.6 9.1 1e-60 205.5 0.3 3.2 2 1 1 3 3 3 3 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 RLN92926.1 - 1.8e-73 244.8 8.4 1.1e-37 128.9 0.9 2.4 2 0 0 2 2 2 2 FAD binding domain AP_endonuc_2 PF01261.24 RLN92926.1 - 0.037 13.5 0.0 10 5.5 0.0 2.8 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel DUF5099 PF17025.5 RLN92926.1 - 0.092 13.2 0.0 4.7 7.7 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5099) DUF3110 PF11360.8 RLN92926.1 - 0.25 11.6 1.0 3.7 7.8 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3110) FAD-oxidase_C PF02913.19 RLN92927.1 - 3.2e-56 190.7 0.2 5.9e-56 189.9 0.2 1.4 1 1 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 RLN92927.1 - 1.2e-29 102.8 0.7 3.3e-29 101.4 0.7 1.7 1 0 0 1 1 1 1 FAD binding domain TB2_DP1_HVA22 PF03134.19 RLN92928.1 - 1.7e-28 98.3 3.3 2.6e-28 97.8 2.5 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family HSP90 PF00183.18 RLN92929.1 - 2.4e-89 300.6 7.2 8.5e-87 292.2 3.5 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 RLN92929.1 - 5.8e-10 39.1 0.1 1.2e-09 38.1 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 RLN92929.1 - 4.8e-07 30.3 0.4 1.1e-06 29.1 0.2 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4119 PF13494.6 RLN92929.1 - 0.22 11.7 1.9 16 5.7 0.3 2.9 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) Pribosyltran_N PF13793.6 RLN92930.1 - 3.1e-43 146.4 0.1 4.8e-42 142.6 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 RLN92930.1 - 5.7e-20 72.1 0.1 1.9e-19 70.4 0.1 1.8 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 RLN92930.1 - 5.7e-07 29.2 0.1 4.8e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain eIF-5a PF01287.20 RLN92931.1 - 1.3e-24 86.0 0.0 1.8e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 RLN92931.1 - 3.5e-05 23.7 0.1 5.1e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Phosphodiest PF01663.22 RLN92932.1 - 4e-14 53.0 0.4 4.3e-10 39.7 0.1 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Serinc PF03348.15 RLN92932.1 - 0.00025 20.1 2.5 0.0018 17.3 0.0 2.7 3 0 0 3 3 3 1 Serine incorporator (Serinc) Sulfatase PF00884.23 RLN92932.1 - 0.017 14.6 0.0 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 Sulfatase KIP1 PF07765.12 RLN92932.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 KIP1-like protein Metalloenzyme PF01676.18 RLN92932.1 - 0.18 11.1 0.0 0.41 10.0 0.0 1.5 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF4131 PF13567.6 RLN92932.1 - 4.4 6.9 10.2 15 5.2 0.1 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) FYVE PF01363.21 RLN92933.1 - 1.5e-06 28.2 8.4 2.6e-06 27.4 8.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger Transp_Tc5_C PF04236.15 RLN92933.1 - 0.049 14.0 1.6 0.049 14.0 1.6 2.0 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain ACPS PF01648.20 RLN92934.1 - 2e-16 60.1 0.0 1.8e-15 57.0 0.0 2.2 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily SLT_L PF14718.6 RLN92934.1 - 0.12 12.6 1.0 0.36 11.0 0.1 2.3 2 0 0 2 2 2 0 Soluble lytic murein transglycosylase L domain SmpA_OmlA PF04355.13 RLN92934.1 - 0.16 11.8 0.1 8.4 6.3 0.1 2.7 3 0 0 3 3 3 0 SmpA / OmlA family vATP-synt_E PF01991.18 RLN92935.1 - 4e-42 143.9 13.0 4.7e-42 143.7 13.0 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit PAXNEB PF05625.11 RLN92935.1 - 0.029 13.5 0.5 0.038 13.1 0.5 1.1 1 0 0 1 1 1 0 PAXNEB protein p450 PF00067.22 RLN92936.1 - 2.9e-66 224.1 0.0 5e-66 223.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Arf PF00025.21 RLN92936.1 - 1.3e-44 151.7 0.1 2.2e-44 151.0 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RLN92936.1 - 7.8e-13 48.7 0.0 1.4e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RLN92936.1 - 2.5e-12 46.7 0.0 5.3e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 RLN92936.1 - 2.6e-12 46.5 0.1 4.6e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RLN92936.1 - 8.9e-10 38.3 3.6 7.3e-06 25.4 0.3 3.0 3 1 1 4 4 4 2 G-protein alpha subunit Gtr1_RagA PF04670.12 RLN92936.1 - 1.3e-08 34.5 0.0 2.2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RLN92936.1 - 3.7e-07 30.2 0.0 9.2e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RLN92936.1 - 0.00045 19.8 0.0 0.054 13.0 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 RLN92936.1 - 0.012 15.4 0.2 0.44 10.3 0.1 2.4 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 RLN92936.1 - 0.032 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.6 RLN92936.1 - 0.046 14.3 0.1 0.12 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain LCD1 PF09798.9 RLN92937.1 - 1.1e-07 30.8 8.2 0.013 14.1 0.0 3.6 1 1 0 2 2 2 1 DNA damage checkpoint protein FKBP_C PF00254.28 RLN92937.1 - 5.1e-05 23.5 0.0 0.00013 22.2 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase YhcG_C PF06250.11 RLN92937.1 - 0.11 12.4 0.1 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 YhcG PDDEXK nuclease domain zf-C2H2 PF00096.26 RLN92938.1 - 1.1e-24 85.4 59.3 8.8e-05 22.7 0.6 9.3 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN92938.1 - 2e-15 56.2 57.9 0.013 16.3 2.6 9.3 9 0 0 9 9 9 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RLN92938.1 - 7.7e-08 32.4 48.7 0.002 18.5 0.0 9.8 10 1 0 10 10 10 4 Zinc-finger double domain zf-C2H2_8 PF15909.5 RLN92938.1 - 3.3e-06 27.3 30.0 0.0055 17.0 4.6 4.6 2 1 4 6 6 6 4 C2H2-type zinc ribbon zf-met PF12874.7 RLN92938.1 - 0.00014 22.1 23.4 0.037 14.4 0.3 6.2 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RLN92938.1 - 0.00017 21.5 38.0 0.00072 19.5 0.6 7.2 6 1 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RLN92938.1 - 0.08 13.3 0.2 0.08 13.3 0.2 7.1 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding PhnA_Zn_Ribbon PF08274.12 RLN92938.1 - 1 9.3 9.5 0.34 10.9 0.1 4.2 4 0 0 4 4 4 0 PhnA Zinc-Ribbon Actin_micro PF17003.5 RLN92938.1 - 1.7 7.7 7.8 41 3.2 7.8 2.9 1 1 0 1 1 1 0 Putative actin-like family zinc_ribbon_4 PF13717.6 RLN92938.1 - 7.6 6.5 9.7 1.2e+02 2.7 0.1 4.8 4 0 0 4 4 4 0 zinc-ribbon domain zf-DNL PF05180.12 RLN92938.1 - 7.7 6.5 8.6 1.1 9.3 0.3 3.2 3 0 0 3 3 3 0 DNL zinc finger zf-RRPl_C4 PF17026.5 RLN92938.1 - 8.9 6.5 12.6 2.9 8.0 2.3 3.1 1 1 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF667 PF05018.13 RLN92939.1 - 1.4e-83 279.1 0.7 1.7e-83 278.9 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) WD40 PF00400.32 RLN92940.1 - 8.5e-16 58.1 7.1 6.2e-05 23.7 0.0 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN92940.1 - 2.2e-08 34.3 0.2 0.0065 16.7 0.0 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 RLN92940.1 - 3.5e-07 30.5 0.5 0.046 14.2 0.0 4.2 4 0 0 4 4 4 2 PQQ-like domain PQQ PF01011.21 RLN92940.1 - 5e-06 26.2 0.4 0.21 11.5 0.1 3.4 3 0 0 3 3 3 2 PQQ enzyme repeat Nup160 PF11715.8 RLN92940.1 - 6.1e-05 21.9 1.4 1.4 7.4 0.1 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 PQQ_2 PF13360.6 RLN92940.1 - 0.01 15.4 1.2 0.32 10.6 0.1 2.7 1 1 1 2 2 2 0 PQQ-like domain Hira PF07569.11 RLN92940.1 - 0.019 14.7 1.4 0.35 10.6 0.0 3.2 2 2 3 5 5 5 0 TUP1-like enhancer of split Nucleoporin_N PF08801.11 RLN92940.1 - 0.019 13.7 0.0 0.05 12.3 0.0 1.6 2 1 0 2 2 2 0 Nup133 N terminal like MIS13 PF08202.11 RLN92941.1 - 0.0021 17.4 0.1 0.0023 17.3 0.1 1.0 1 0 0 1 1 1 1 Mis12-Mtw1 protein family DUF948 PF06103.11 RLN92941.1 - 0.017 15.4 3.4 0.03 14.6 3.4 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF5089 PF17002.5 RLN92941.1 - 0.018 14.9 0.4 0.021 14.7 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) IFT57 PF10498.9 RLN92941.1 - 0.048 12.6 1.0 0.059 12.3 1.0 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 PTRF_SDPR PF15237.6 RLN92941.1 - 0.049 13.2 3.9 0.061 12.9 3.9 1.0 1 0 0 1 1 1 0 PTRF/SDPR family TBCA PF02970.16 RLN92941.1 - 0.14 12.5 2.3 4.3 7.7 0.2 2.1 1 1 1 2 2 2 0 Tubulin binding cofactor A DUF3235 PF11574.8 RLN92941.1 - 0.49 11.3 4.3 34 5.4 4.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3235) tRNA-synt_2b PF00587.25 RLN92942.1 - 2.7e-27 95.9 0.0 4.7e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 RLN92942.1 - 5e-11 42.8 4.1 8.6e-11 42.0 4.1 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Sds3 PF08598.11 RLN92943.1 - 5e-07 29.9 2.6 5e-07 29.9 2.6 1.8 2 0 0 2 2 2 1 Sds3-like Rhabdo_ncap_2 PF03216.13 RLN92943.1 - 0.048 13.1 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleoprotein DUF5082 PF16888.5 RLN92943.1 - 0.23 11.7 1.3 24 5.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF1977 PF09320.11 RLN92943.1 - 0.23 11.7 1.9 0.74 10.1 1.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1977) ERp29 PF07749.12 RLN92943.1 - 3.5 8.6 7.1 1.6 9.7 0.5 2.8 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain Sdh5 PF03937.16 RLN92945.1 - 2.9e-22 78.4 0.1 4.5e-22 77.8 0.1 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Galactosyl_T PF01762.21 RLN92945.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Galactosyltransferase AdoHcyase PF05221.17 RLN92946.1 - 1.6e-142 474.1 0.0 1.8e-142 473.9 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 RLN92946.1 - 1.4e-81 272.3 4.2 2.1e-81 271.7 4.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 RLN92946.1 - 6.2e-10 38.7 0.3 1e-09 38.0 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 RLN92946.1 - 1.3e-05 24.8 0.3 2.7e-05 23.8 0.3 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 RLN92946.1 - 0.0015 18.7 0.9 0.031 14.5 0.8 2.8 2 1 0 2 2 2 1 TrkA-N domain Shikimate_DH PF01488.20 RLN92946.1 - 0.0021 18.1 0.5 0.0061 16.6 0.5 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 RLN92946.1 - 0.0029 16.9 3.2 0.012 14.9 3.2 1.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ELFV_dehydrog PF00208.21 RLN92946.1 - 0.006 16.3 0.2 0.012 15.3 0.2 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUP PF00674.18 RLN92946.1 - 0.024 14.8 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 DUP family NAD_binding_7 PF13241.6 RLN92946.1 - 0.028 14.9 0.5 0.093 13.2 0.5 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 RLN92946.1 - 0.12 12.2 0.5 0.22 11.4 0.5 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain X8 PF07983.13 RLN92947.1 - 7.2e-10 39.4 0.4 1.9e-09 38.1 0.4 1.8 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 RLN92947.1 - 1.1e-09 38.1 1.2 3.4e-09 36.5 1.2 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.24 RLN92947.1 - 0.0079 15.7 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel LapA_dom PF06305.11 RLN92947.1 - 0.54 10.1 1.2 0.93 9.3 1.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Cellulase PF00150.18 RLN92948.1 - 3.6e-11 43.0 1.2 6.4e-11 42.2 1.2 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) X8 PF07983.13 RLN92948.1 - 1.3e-09 38.6 0.1 4.9e-09 36.8 0.1 2.1 1 0 0 1 1 1 1 X8 domain AP_endonuc_2 PF01261.24 RLN92948.1 - 0.0027 17.2 0.0 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyco_hydro_42 PF02449.15 RLN92948.1 - 3.6 6.8 9.0 0.4 10.0 3.6 2.1 3 1 0 3 3 3 0 Beta-galactosidase X8 PF07983.13 RLN92949.1 - 1e-10 42.1 0.3 3.2e-10 40.6 0.3 1.9 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 RLN92949.1 - 5.5e-10 39.1 1.9 1.1e-09 38.1 1.9 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.24 RLN92949.1 - 0.014 14.8 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Prefoldin PF02996.17 RLN92950.1 - 2.5e-05 24.2 0.2 4.4e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 Prefoldin subunit Mst1_SARAH PF11629.8 RLN92950.1 - 0.095 12.8 0.2 1 9.5 0.1 2.1 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 THUMP PF02926.17 RLN92951.1 - 2.3e-15 57.0 0.9 5.8e-15 55.6 0.9 1.7 1 0 0 1 1 1 1 THUMP domain TarH PF02203.15 RLN92951.1 - 0.1 12.5 1.8 2 8.3 1.7 2.2 2 0 0 2 2 2 0 Tar ligand binding domain homologue zf-DNL PF05180.12 RLN92951.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 DNL zinc finger Clathrin_lg_ch PF01086.17 RLN92952.1 - 5.2e-12 46.3 11.1 9.1e-09 35.7 8.1 2.1 2 0 0 2 2 2 2 Clathrin light chain Utp13 PF08625.11 RLN92953.1 - 0.12 12.3 1.1 0.34 10.8 1.1 1.7 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain Adaptin_binding PF10199.9 RLN92954.1 - 2.4e-18 66.9 5.4 5.2e-18 65.8 5.4 1.6 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Ras PF00071.22 RLN92954.1 - 0.0006 19.5 0.3 0.0012 18.5 0.3 1.4 1 0 0 1 1 1 1 Ras family Transglut_core PF01841.19 RLN92954.1 - 0.062 13.8 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily NPR1_interact PF15699.5 RLN92954.1 - 0.23 12.1 0.4 0.23 12.1 0.4 2.9 3 0 0 3 3 3 0 NPR1 interacting Cwf_Cwc_15 PF04889.12 RLN92954.1 - 0.81 9.4 7.3 1.2 8.8 7.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pkinase PF00069.25 RLN92955.1 - 7.7e-64 215.6 0.0 1.2e-63 215.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN92955.1 - 2.6e-25 89.2 0.0 4.3e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN92955.1 - 7.7e-06 25.4 0.0 0.015 14.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like DUF2635 PF10948.8 RLN92955.1 - 0.0085 15.8 0.0 0.63 9.8 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2635) Kdo PF06293.14 RLN92955.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN92955.1 - 0.017 15.0 0.2 0.059 13.3 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pol_alpha_B_N PF08418.10 RLN92956.1 - 3.6e-07 30.4 0.0 5e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Exo_endo_phos PF03372.23 RLN92957.1 - 3.6e-08 33.2 0.0 7.2e-08 32.2 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C6H2 PF15801.5 RLN92957.1 - 0.17 12.2 0.2 1.8 8.9 0.1 2.3 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Myb_DNA-binding PF00249.31 RLN92958.1 - 9.5e-15 54.5 0.4 4.1e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN92958.1 - 0.00026 21.2 0.1 0.046 14.0 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN92958.1 - 0.12 12.2 0.3 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Myb DNA-binding like baeRF_family12 PF18856.1 RLN92958.1 - 0.34 11.5 0.1 0.34 11.5 0.1 3.0 3 1 1 4 4 4 0 Bacterial archaeo-eukaryotic release factor family 12 DUF572 PF04502.13 RLN92960.1 - 0.51 9.9 17.9 0.7 9.5 17.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) fn3 PF00041.21 RLN92961.1 - 3.4e-08 33.7 0.2 0.0052 17.1 0.0 4.1 2 2 0 2 2 2 2 Fibronectin type III domain PA PF02225.22 RLN92961.1 - 7.3e-06 25.9 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 PA domain Pur_ac_phosph_N PF16656.5 RLN92961.1 - 0.021 15.4 0.0 0.75 10.4 0.0 2.4 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain CAMSAP_CKK PF08683.11 RLN92962.1 - 1.3e-21 76.9 0.1 2.8e-21 75.9 0.1 1.5 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated Lig_chan PF00060.26 RLN92963.1 - 0.023 14.5 0.0 0.025 14.4 0.0 1.1 1 0 0 1 1 1 0 Ligand-gated ion channel DUF4381 PF14316.6 RLN92963.1 - 0.1 12.8 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Herpes_gE PF02480.16 RLN92963.1 - 0.14 10.9 0.0 0.14 10.8 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF5453 PF17534.2 RLN92963.1 - 0.14 12.1 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5453) KOG2701 PF09762.9 RLN92965.1 - 3.6e-37 128.3 0.0 3.6e-37 128.3 0.0 3.7 3 1 0 3 3 3 1 Coiled-coil domain-containing protein (DUF2037) RNase_PH PF01138.21 RLN92967.1 - 4.6e-16 59.5 0.3 3.8e-15 56.5 0.2 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RLN92967.1 - 2.4e-14 53.1 0.1 4.2e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 MIF4G PF02854.19 RLN92969.1 - 1.8e-45 155.2 1.7 6.6e-19 68.4 0.4 4.3 3 1 0 3 3 3 3 MIF4G domain Mito_carr PF00153.27 RLN92969.1 - 4.1e-27 93.9 3.3 1.2e-16 60.4 0.1 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein Upf2 PF04050.14 RLN92969.1 - 8.9e-19 68.6 8.4 8.9e-19 68.6 8.4 3.2 2 2 1 3 3 1 1 Up-frameshift suppressor 2 YL1 PF05764.13 RLN92969.1 - 0.00032 20.9 21.4 0.00032 20.9 21.4 2.5 2 0 0 2 2 2 1 YL1 nuclear protein SDA1 PF05285.12 RLN92969.1 - 0.00047 19.7 27.3 0.00047 19.7 27.3 2.3 2 0 0 2 2 2 1 SDA1 Nop14 PF04147.12 RLN92969.1 - 0.00069 18.0 47.7 0.021 13.1 35.3 2.8 3 0 0 3 3 3 2 Nop14-like family CDC45 PF02724.14 RLN92969.1 - 0.046 12.0 28.5 0.0052 15.1 16.9 2.2 2 0 0 2 2 2 0 CDC45-like protein DUF2498 PF10692.9 RLN92969.1 - 0.12 12.3 0.4 0.41 10.6 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2498) RR_TM4-6 PF06459.12 RLN92969.1 - 5.9 6.6 28.7 1.6 8.5 2.6 2.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 BUD22 PF09073.10 RLN92969.1 - 7.8 5.7 49.4 7.4 5.8 33.2 2.4 2 0 0 2 2 2 0 BUD22 Mpp10 PF04006.12 RLN92969.1 - 9.8 4.5 53.6 0.99 7.8 36.6 2.5 3 0 0 3 3 3 0 Mpp10 protein Elicitin PF00964.17 RLN92970.1 - 9.5e-43 144.2 13.7 6.9e-22 77.4 3.2 2.3 2 0 0 2 2 2 2 Elicitin PDEase_I PF00233.19 RLN92971.1 - 8.6e-17 61.6 0.0 9.8e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase LRR_12 PF18837.1 RLN92971.1 - 0.068 12.8 0.1 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeat CD36 PF01130.21 RLN92972.1 - 3.8e-23 81.8 0.0 4.6e-16 58.4 0.0 3.2 3 0 0 3 3 3 3 CD36 family RNase_PH PF01138.21 RLN92973.1 - 1.2e-15 58.2 0.1 1.5e-15 57.9 0.1 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Ras PF00071.22 RLN92974.1 - 3.7e-39 133.9 0.0 5.4e-38 130.1 0.0 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RLN92974.1 - 1.3e-28 99.6 0.0 2.9e-28 98.5 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN92974.1 - 5.9e-09 35.6 0.0 1.1e-07 31.4 0.0 2.5 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RLN92974.1 - 0.00014 21.4 0.0 0.0085 15.7 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 RLN92974.1 - 0.00067 19.1 0.0 0.0022 17.4 0.0 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RLN92974.1 - 0.0025 17.9 0.0 0.0045 17.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RLN92974.1 - 0.0031 17.4 0.0 0.55 10.1 0.0 2.8 2 1 1 3 3 3 1 RsgA GTPase SRPRB PF09439.10 RLN92974.1 - 0.016 14.6 0.0 0.047 13.1 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 RLN92974.1 - 0.085 12.6 0.1 5.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 RLN92974.1 - 0.13 11.6 0.0 0.43 10.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein OSCP PF00213.18 RLN92975.1 - 4.3e-45 153.9 2.8 7.4e-45 153.1 2.8 1.4 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit TFIIA_gamma_N PF02268.16 RLN92975.1 - 0.00071 19.5 0.1 0.0016 18.4 0.1 1.6 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain DUF4834 PF16118.5 RLN92977.1 - 5.7 8.0 8.0 39 5.3 8.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2870 PF11069.8 RLN92978.1 - 3.4e-37 126.7 0.4 5.3e-37 126.1 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) TTL PF03133.15 RLN92979.1 - 4.2e-60 203.4 0.0 6.7e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RLN92979.1 - 2.4e-07 30.3 0.0 1e-05 24.9 0.0 2.7 2 1 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RLN92979.1 - 0.11 11.7 0.0 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp PNISR PF15996.5 RLN92979.1 - 0.87 9.8 8.3 1.6 9.0 8.3 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Kelch_3 PF13415.6 RLN92980.1 - 9.6e-41 137.4 9.6 2.5e-07 30.8 0.1 7.9 7 0 0 7 7 7 7 Galactose oxidase, central domain Kelch_1 PF01344.25 RLN92980.1 - 2e-35 120.1 0.0 5.9e-06 25.8 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 RLN92980.1 - 6e-34 115.8 5.9 6.9e-06 26.0 0.0 6.7 5 2 1 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 RLN92980.1 - 5.4e-29 99.5 0.1 9.6e-06 25.7 0.0 6.3 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.15 RLN92980.1 - 7.2e-29 98.7 1.3 2.1e-05 24.3 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 RLN92980.1 - 1.6e-25 88.6 0.1 1.9e-06 27.7 0.0 5.7 5 0 0 5 5 5 5 Kelch motif BTB PF00651.31 RLN92980.1 - 1.2e-15 57.7 0.5 1.4e-12 47.8 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain TRP PF06011.12 RLN92981.1 - 1.1e-12 47.4 20.0 1.1e-12 47.4 20.0 2.4 2 1 1 3 3 3 2 Transient receptor potential (TRP) ion channel HTH_32 PF13565.6 RLN92982.1 - 8.5e-05 23.1 0.1 0.02 15.5 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_17 PF12728.7 RLN92982.1 - 0.0001 22.4 0.2 0.083 13.1 0.1 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.6 RLN92982.1 - 0.0022 17.7 0.7 0.048 13.5 0.1 2.5 2 1 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 RLN92982.1 - 0.032 14.3 1.1 0.15 12.2 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_6 PF01418.17 RLN92982.1 - 0.033 14.2 0.0 9.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_11 PF08279.12 RLN92982.1 - 0.033 14.1 0.5 1.8 8.5 0.1 2.4 2 0 0 2 2 2 0 HTH domain HTH_38 PF13936.6 RLN92982.1 - 0.13 12.0 1.9 5.6 6.8 0.2 3.1 2 1 0 2 2 2 0 Helix-turn-helix domain Ank_2 PF12796.7 RLN92985.1 - 1.3e-30 105.8 10.4 2.8e-10 40.7 0.1 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN92985.1 - 1.8e-21 76.2 2.0 7.4e-06 26.4 0.0 5.0 4 1 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN92985.1 - 3.3e-19 66.9 7.3 0.022 15.2 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 RLN92985.1 - 3.4e-18 65.5 12.0 0.0023 18.2 0.2 6.3 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN92985.1 - 1e-13 51.0 15.0 0.0076 16.7 0.2 6.8 7 0 0 7 7 7 4 Ankyrin repeat DUF1295 PF06966.12 RLN92987.1 - 1.4e-61 208.0 0.2 1.8e-61 207.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 RLN92987.1 - 2.8e-06 27.4 0.1 8.6e-06 25.8 0.1 1.9 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 RLN92987.1 - 0.00017 22.0 0.1 0.00017 22.0 0.1 2.6 2 2 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 RLN92987.1 - 0.00044 20.6 0.0 0.00044 20.6 0.0 2.3 4 0 0 4 4 4 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 RLN92987.1 - 0.016 14.0 0.1 0.035 12.9 0.1 1.6 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family Pmp3 PF01679.17 RLN92988.1 - 5.3e-17 61.7 12.3 4.1e-16 58.9 12.3 1.9 1 1 0 1 1 1 1 Proteolipid membrane potential modulator TPR_1 PF00515.28 RLN92989.1 - 1.3e-05 24.8 2.6 0.00018 21.2 0.6 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 RLN92989.1 - 1.9e-05 24.4 6.6 7.5e-05 22.5 0.6 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN92989.1 - 0.00063 19.4 1.0 0.00063 19.4 1.0 2.4 3 0 0 3 3 3 1 TPR repeat TPR_8 PF13181.6 RLN92989.1 - 0.0019 18.3 2.8 0.02 15.1 0.3 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN92989.1 - 0.0038 17.5 0.4 0.0038 17.5 0.4 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN92989.1 - 0.074 13.6 8.8 0.44 11.1 3.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Pex26 PF07163.12 RLN92989.1 - 0.11 11.8 0.6 0.16 11.3 0.6 1.2 1 0 0 1 1 1 0 Pex26 protein TPR_9 PF13371.6 RLN92989.1 - 0.53 10.5 5.1 2.3 8.4 0.3 3.0 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN92989.1 - 0.61 11.0 6.0 13 6.9 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN92989.1 - 4.9 7.9 16.1 33 5.2 8.9 3.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Big_7 PF17957.1 RLN92990.1 - 0.00025 21.8 0.0 0.021 15.6 0.0 2.9 2 0 0 2 2 2 1 Bacterial Ig domain BiPBP_C PF06832.12 RLN92990.1 - 0.008 16.2 0.0 0.045 13.8 0.0 2.2 2 0 0 2 2 2 1 Penicillin-Binding Protein C-terminus Family MGC-24 PF05283.11 RLN92990.1 - 1.5 9.3 8.8 1.5 9.3 7.3 1.7 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Shisa PF13908.6 RLN92991.1 - 9.2e-05 22.8 0.0 0.00011 22.5 0.0 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator WBP-1 PF11669.8 RLN92991.1 - 0.0002 22.0 0.0 0.00025 21.6 0.0 1.2 1 0 0 1 1 1 1 WW domain-binding protein 1 TMEM51 PF15345.6 RLN92991.1 - 0.0021 17.9 0.5 0.0021 17.9 0.5 1.5 1 1 1 2 2 2 1 Transmembrane protein 51 Rhabdo_glycop PF00974.18 RLN92991.1 - 0.0031 16.0 0.5 0.0036 15.8 0.5 1.1 1 0 0 1 1 1 1 Rhabdovirus spike glycoprotein DUF4381 PF14316.6 RLN92991.1 - 0.029 14.6 3.3 0.039 14.2 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Herpes_glycop PF01528.16 RLN92991.1 - 0.051 12.4 0.2 0.063 12.1 0.2 1.0 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Zeta_toxin PF06414.12 RLN92991.1 - 0.059 12.6 0.3 0.074 12.3 0.3 1.1 1 0 0 1 1 1 0 Zeta toxin CMV_US PF08001.11 RLN92991.1 - 0.062 12.6 0.0 0.073 12.3 0.0 1.0 1 0 0 1 1 1 0 CMV US MSP1a PF11670.8 RLN92991.1 - 0.068 12.5 0.1 0.083 12.2 0.1 1.1 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) EphA2_TM PF14575.6 RLN92991.1 - 0.07 14.0 1.7 0.11 13.4 1.7 1.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Tweety PF04906.13 RLN92991.1 - 0.074 11.7 0.3 0.081 11.6 0.3 1.2 1 0 0 1 1 1 0 Tweety Comm PF15957.5 RLN92991.1 - 0.1 13.0 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Commissureless RCR PF12273.8 RLN92991.1 - 0.1 13.3 5.6 0.36 11.5 5.6 1.7 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red MFS_4 PF06779.14 RLN92991.1 - 0.11 11.8 0.2 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB PAG PF15347.6 RLN92991.1 - 0.14 11.2 1.7 0.13 11.2 1.2 1.2 1 1 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Mucin PF01456.17 RLN92991.1 - 0.19 11.7 3.1 0.24 11.4 3.1 1.4 1 1 0 1 1 1 0 Mucin-like glycoprotein TMEM154 PF15102.6 RLN92991.1 - 0.23 11.4 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family CCD48 PF15799.5 RLN92992.1 - 0.0005 18.5 1.9 0.00059 18.3 1.9 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 SANT_DAMP1_like PF16282.5 RLN92993.1 - 0.028 14.6 0.3 0.067 13.4 0.3 1.7 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 DUF1772 PF08592.11 RLN92994.1 - 4.1e-09 36.9 0.1 8e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) eRF1_1 PF03463.15 RLN92995.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 eRF1 domain 1 Bcl-2 PF00452.19 RLN92995.1 - 0.08 13.6 0.4 0.69 10.6 0.1 2.5 2 0 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family AAA_16 PF13191.6 RLN92996.1 - 0.024 15.0 0.0 0.054 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 RLN92997.1 - 1.5e-11 44.7 0.0 7.3e-10 39.2 0.0 2.3 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 RLN92997.1 - 2.6e-07 30.7 0.0 5.6e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 RLN92997.1 - 0.0013 18.9 0.1 1.5 9.1 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 RLN92997.1 - 0.012 15.6 0.5 0.52 10.2 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase FeoB_N PF02421.18 RLN92997.1 - 0.017 14.7 0.2 2.4 7.6 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B AIG1 PF04548.16 RLN92997.1 - 0.056 12.8 0.0 1.8 7.8 0.0 2.3 2 0 0 2 2 2 0 AIG1 family GTP_EFTU PF00009.27 RLN92997.1 - 0.06 12.9 0.0 7.5 6.0 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Septin PF00735.18 RLN92997.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Septin G-alpha PF00503.20 RLN92997.1 - 0.18 11.0 0.1 0.75 8.9 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit Ras PF00071.22 RLN92997.1 - 0.18 11.4 0.0 2.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Ras family WD40 PF00400.32 RLN92998.1 - 4.5e-30 103.2 7.1 3.7e-05 24.4 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN92998.1 - 5e-06 26.7 0.0 0.0014 18.9 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RLN92998.1 - 0.0015 17.9 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 2 WD40-like domain ELYS-bb PF16687.5 RLN92998.1 - 0.029 13.0 0.0 0.081 11.5 0.0 1.6 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin Ge1_WD40 PF16529.5 RLN92998.1 - 0.031 13.2 0.0 2.6 6.9 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ccdc124 PF06244.12 RLN92998.1 - 2.7 8.6 6.6 5.2 7.6 6.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 Spt20 PF12090.8 RLN92999.1 - 1.8 8.2 9.8 2 8.0 9.8 1.0 1 0 0 1 1 1 0 Spt20 family Actin PF00022.19 RLN93000.1 - 3.3e-101 338.9 0.0 3.8e-101 338.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 RLN93000.1 - 0.0017 17.3 0.0 0.042 12.7 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Kinesin PF00225.23 RLN93001.1 - 5e-48 163.7 0.4 4e-33 114.7 0.1 2.4 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 RLN93001.1 - 2.4e-16 60.0 0.0 5.5e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding HrpB7 PF09486.10 RLN93001.1 - 0.0019 18.6 19.2 0.0036 17.7 5.0 2.9 1 1 1 2 2 2 1 Bacterial type III secretion protein (HrpB7) Seryl_tRNA_N PF02403.22 RLN93001.1 - 0.0028 17.9 6.8 0.0028 17.9 6.8 3.1 2 1 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain YabA PF06156.13 RLN93001.1 - 0.015 15.9 15.3 0.065 13.9 2.5 4.3 3 1 1 5 5 5 0 Initiation control protein YabA BLOC1_2 PF10046.9 RLN93001.1 - 0.018 15.4 15.6 0.085 13.2 1.2 4.7 2 1 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.6 RLN93001.1 - 0.032 12.9 17.3 0.047 12.3 16.7 1.5 2 0 0 2 2 2 0 AAA domain Synaptobrevin PF00957.21 RLN93001.1 - 0.22 11.4 0.6 0.64 9.8 0.6 1.8 1 0 0 1 1 1 0 Synaptobrevin Mvb12 PF09452.10 RLN93001.1 - 0.26 11.7 2.0 10 6.6 0.2 2.9 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 DUF5082 PF16888.5 RLN93001.1 - 0.29 11.4 10.8 0.24 11.7 4.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF3498 PF12004.8 RLN93001.1 - 0.31 10.2 13.4 0.44 9.7 13.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Rab5-bind PF09311.11 RLN93001.1 - 0.32 10.3 23.2 0.16 11.3 7.3 2.4 2 1 1 3 3 2 0 Rabaptin-like protein CortBP2 PF09727.9 RLN93001.1 - 0.35 10.8 23.3 0.061 13.2 11.2 2.4 1 1 1 2 2 2 0 Cortactin-binding protein-2 GAS PF13851.6 RLN93001.1 - 0.38 10.1 23.6 0.084 12.2 8.8 2.6 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding XhlA PF10779.9 RLN93001.1 - 0.56 10.4 5.4 3.8 7.8 4.3 2.7 1 1 1 2 2 2 0 Haemolysin XhlA Filament PF00038.21 RLN93001.1 - 0.57 9.7 24.3 2.2 7.8 24.3 1.9 1 1 0 1 1 1 0 Intermediate filament protein UPF0242 PF06785.11 RLN93001.1 - 0.63 10.1 25.1 0.63 10.1 10.3 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4094 PF13334.6 RLN93001.1 - 0.78 10.2 4.5 10 6.7 2.5 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) COG5 PF10392.9 RLN93001.1 - 0.8 9.9 10.5 0.36 11.0 2.0 3.6 3 1 1 4 4 4 0 Golgi transport complex subunit 5 HMMR_N PF15905.5 RLN93001.1 - 0.87 9.0 22.6 8.8 5.7 17.3 2.3 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF724 PF05266.14 RLN93001.1 - 0.91 9.3 18.5 0.11 12.3 6.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) FlaC_arch PF05377.11 RLN93001.1 - 0.91 10.0 6.5 38 4.8 4.3 3.7 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 RLN93001.1 - 1.1 9.8 7.9 0.59 10.6 1.2 3.3 3 1 0 3 3 2 0 Nucleopolyhedrovirus P10 protein TMF_TATA_bd PF12325.8 RLN93001.1 - 1.1 9.5 24.0 0.059 13.6 8.2 3.3 1 1 2 3 3 2 0 TATA element modulatory factor 1 TATA binding Leu_zip PF15294.6 RLN93001.1 - 1.2 8.6 18.6 3.2 7.2 9.1 2.5 1 1 1 2 2 2 0 Leucine zipper MAD PF05557.13 RLN93001.1 - 1.3 7.3 25.8 2.5 6.3 21.6 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF2407_C PF13373.6 RLN93001.1 - 1.3 9.2 3.9 4.2 7.6 0.3 2.3 2 0 0 2 2 2 0 DUF2407 C-terminal domain HOOK PF05622.12 RLN93001.1 - 1.4 7.0 24.6 0.18 9.9 16.1 2.1 1 1 1 2 2 2 0 HOOK protein TPR_MLP1_2 PF07926.12 RLN93001.1 - 1.5 8.9 28.4 0.17 12.0 3.8 3.5 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF489 PF04356.12 RLN93001.1 - 1.5 8.8 9.3 0.97 9.4 0.8 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF489) LXG PF04740.12 RLN93001.1 - 2 8.1 12.7 0.34 10.6 2.6 3.6 2 1 0 3 3 3 0 LXG domain of WXG superfamily DUF2959 PF11172.8 RLN93001.1 - 2.2 8.4 14.5 0.3 11.2 4.2 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2959) DUF1664 PF07889.12 RLN93001.1 - 2.4 8.2 11.3 0.57 10.2 1.3 3.4 2 1 1 4 4 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 RLN93001.1 - 2.6 8.2 13.1 0.19 11.9 4.9 2.6 2 1 0 3 3 2 0 Fibrinogen alpha/beta chain family DUF4363 PF14276.6 RLN93001.1 - 3.4 7.8 9.7 3.2 7.9 0.8 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF4363) PKcGMP_CC PF16808.5 RLN93001.1 - 3.6 7.5 14.8 6.1 6.8 1.2 4.3 3 1 1 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4164 PF13747.6 RLN93001.1 - 4.1 7.8 29.1 3.6 7.9 7.8 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) CHDCT2 PF08074.11 RLN93001.1 - 4.1 7.5 6.6 6.8 6.8 4.4 2.6 2 1 0 2 2 2 0 CHDCT2 (NUC038) domain DUF4407 PF14362.6 RLN93001.1 - 4.5 6.5 19.4 41 3.4 19.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 RLN93001.1 - 4.9 6.6 20.2 2 7.9 9.7 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit Syntaxin-6_N PF09177.11 RLN93001.1 - 6 7.5 14.9 20 5.8 3.9 4.1 2 2 2 4 4 4 0 Syntaxin 6, N-terminal HXXSHH PF07586.11 RLN93001.1 - 6.4 6.2 11.7 0.13 11.8 3.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1552) Sec8_exocyst PF04048.14 RLN93001.1 - 7.3 6.5 9.6 4 7.3 5.1 2.8 3 1 0 3 3 1 0 Sec8 exocyst complex component specific domain Cytochrom_B562 PF07361.11 RLN93001.1 - 8.1 7.2 9.1 0.75 10.5 1.7 2.6 1 1 2 3 3 2 0 Cytochrome b562 DUF16 PF01519.16 RLN93001.1 - 9.3 6.8 13.5 0.36 11.3 3.6 2.7 2 1 0 3 3 2 0 Protein of unknown function DUF16 Tho2 PF11262.8 RLN93001.1 - 9.5 5.3 13.4 0.078 12.2 2.8 2.3 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 CENP-K PF11802.8 RLN93001.1 - 9.7 5.7 16.7 15 5.1 15.6 1.9 2 1 0 2 2 2 0 Centromere-associated protein K GDI PF00996.18 RLN93003.1 - 1.7e-197 656.2 0.0 2e-197 656.0 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 RLN93003.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ABC2_membrane PF01061.24 RLN93004.1 - 1.1e-30 106.7 28.7 1.1e-30 106.7 28.7 1.7 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN93004.1 - 3.8e-11 42.7 2.0 4.6e-11 42.5 0.0 2.2 2 0 0 2 2 2 1 CDR ABC transporter PDR_assoc PF08370.11 RLN93004.1 - 0.25 11.1 0.1 0.25 11.1 0.1 2.9 3 0 0 3 3 3 0 Plant PDR ABC transporter associated GRASP55_65 PF04495.14 RLN93005.1 - 2.3e-38 131.6 0.0 1.1e-24 87.4 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 RLN93005.1 - 1.1e-08 35.3 0.0 0.0062 16.8 0.0 2.9 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 RLN93005.1 - 2.7e-07 30.3 0.0 0.023 14.5 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 RLN93005.1 - 0.013 15.9 0.0 0.99 9.8 0.0 2.3 2 0 0 2 2 2 0 PDZ domain HMG_CoA_synt_N PF01154.17 RLN93006.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal cNMP_binding PF00027.29 RLN93007.1 - 3.7e-48 161.5 3.1 1.6e-12 47.3 0.1 5.9 6 0 0 6 6 6 5 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN93007.1 - 4.9e-39 134.0 39.6 4.2e-15 55.6 3.7 4.4 4 0 0 4 4 4 4 Ion transport protein Se-cys_synth_N PF12390.8 RLN93007.1 - 0.3 11.3 3.7 26 5.1 0.1 3.8 4 0 0 4 4 4 0 Selenocysteine synthase N terminal Ion_trans_2 PF07885.16 RLN93007.1 - 1.5 8.8 13.5 9.5 6.3 0.0 5.4 5 0 0 5 5 5 0 Ion channel Ion_trans PF00520.31 RLN93008.1 - 4.8e-25 88.2 7.2 9.6e-15 54.5 3.2 2.2 2 0 0 2 2 2 2 Ion transport protein cNMP_binding PF00027.29 RLN93008.1 - 8e-13 48.3 0.0 1.4e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 RLN93008.1 - 0.00013 21.8 0.2 0.00013 21.8 0.2 3.2 3 0 0 3 3 3 2 Ion channel DUF2072 PF09845.9 RLN93009.1 - 0.04 14.2 1.1 0.06 13.6 0.7 1.4 1 1 0 1 1 1 0 Zn-ribbon containing protein Ureidogly_lyase PF04115.12 RLN93009.1 - 0.071 12.9 1.7 0.11 12.2 1.7 1.4 1 0 0 1 1 1 0 Ureidoglycolate lyase MMR_HSR1_C PF08438.10 RLN93009.1 - 0.91 10.1 3.8 3.1 8.4 0.7 2.2 1 1 1 2 2 2 0 GTPase of unknown function C-terminal Sas10_Utp3 PF04000.15 RLN93010.1 - 0.028 15.0 0.4 0.067 13.8 0.4 1.7 1 0 0 1 1 1 0 Sas10/Utp3/C1D family DUF4570 PF15134.6 RLN93010.1 - 7.9 6.5 7.0 0.85 9.7 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) Pkinase PF00069.25 RLN93013.1 - 4.5e-79 265.5 0.0 5.3e-79 265.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN93013.1 - 6.6e-35 120.6 0.0 8.7e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN93013.1 - 7.4e-06 25.0 0.0 1.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN93013.1 - 0.00044 19.7 0.0 0.00086 18.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN93013.1 - 0.00062 19.2 0.1 0.00094 18.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 RLN93013.1 - 0.027 13.5 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase GBP PF02263.19 RLN93015.1 - 1.3e-63 214.8 0.0 1.3e-63 214.8 0.0 2.3 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 RLN93015.1 - 8.8e-07 28.6 30.5 8.8e-07 28.6 30.5 3.4 1 1 1 2 2 2 1 Guanylate-binding protein, C-terminal domain MMR_HSR1 PF01926.23 RLN93015.1 - 0.002 18.2 0.0 0.0076 16.3 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF5082 PF16888.5 RLN93015.1 - 0.16 12.3 30.3 1.7 8.9 4.7 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) Polysacc_deac_1 PF01522.21 RLN93015.1 - 1.9 8.4 6.0 18 5.3 0.8 3.0 4 0 0 4 4 4 0 Polysaccharide deacetylase Rhomboid PF01694.22 RLN93016.1 - 1.6e-06 28.2 17.4 5.1e-05 23.3 2.4 3.4 3 1 1 4 4 4 3 Rhomboid family Proteasome PF00227.26 RLN93017.1 - 8.4e-52 175.4 0.0 1.1e-51 175.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RLN93017.1 - 2.7e-10 39.7 0.4 5.9e-10 38.7 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature ABC_membrane PF00664.23 RLN93018.1 - 2.1e-42 145.7 1.9 2.4e-42 145.5 1.9 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region UPF0542 PF15086.6 RLN93018.1 - 0.034 14.1 0.1 0.07 13.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 DUF2207 PF09972.9 RLN93018.1 - 1.3 7.8 2.7 1.5 7.5 2.7 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) LRR_6 PF13516.6 RLN93019.1 - 6.4e-32 106.9 22.8 0.00013 21.7 0.1 11.3 12 0 0 12 12 12 8 Leucine Rich repeat LRR_4 PF12799.7 RLN93019.1 - 5.7e-12 45.6 18.3 0.029 14.8 0.4 7.9 4 2 6 10 10 10 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN93019.1 - 1.3e-07 31.3 19.3 0.13 12.0 3.7 7.2 4 2 2 6 6 6 3 Leucine rich repeat LRR_1 PF00560.33 RLN93019.1 - 2.8e-06 27.1 9.6 95 4.2 0.0 8.7 9 1 0 9 9 9 0 Leucine Rich Repeat LRR_2 PF07723.13 RLN93019.1 - 0.00031 21.3 0.1 1.1 10.0 0.0 4.3 4 0 0 4 4 4 1 Leucine Rich Repeat Pentapeptide_4 PF13599.6 RLN93019.1 - 0.24 11.6 3.3 0.93 9.7 1.9 2.6 2 2 1 3 3 3 0 Pentapeptide repeats (9 copies) DUF5372 PF17342.2 RLN93021.1 - 0.084 13.3 0.2 0.17 12.3 0.2 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5372) Flot PF15975.5 RLN93021.1 - 3.4 7.9 5.7 1.9 8.7 3.5 1.6 1 1 1 2 2 2 0 Flotillin LpxB PF02684.15 RLN93022.1 - 0.013 14.4 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase ASCH PF04266.14 RLN93022.1 - 0.13 12.9 0.1 0.32 11.6 0.1 1.7 1 1 0 1 1 1 0 ASCH domain Pkinase PF00069.25 RLN93023.1 - 2.8e-68 230.2 0.0 3.6e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN93023.1 - 3.6e-39 134.6 0.0 4.8e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN93023.1 - 3.9e-05 23.1 0.0 0.00034 20.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RLN93023.1 - 0.0079 15.0 0.0 0.025 13.4 0.0 1.6 1 1 0 1 1 1 1 Fungal protein kinase ACOX PF01756.19 RLN93025.1 - 1.4e-47 161.6 0.0 2.1e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase DUF3450 PF11932.8 RLN93026.1 - 0.51 9.6 13.2 0.088 12.1 6.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) YabA PF06156.13 RLN93026.1 - 0.56 10.9 3.2 2.5 8.8 0.1 2.4 2 0 0 2 2 2 0 Initiation control protein YabA Com_YlbF PF06133.11 RLN93026.1 - 1.5 9.5 8.0 6.1 7.5 0.7 2.6 3 0 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA CENP-F_leu_zip PF10473.9 RLN93026.1 - 2.4 8.2 13.6 24 5.0 11.9 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GlcNAc PF11397.8 RLN93028.1 - 3.6e-44 151.6 0.0 1.1e-37 130.4 0.0 2.7 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) GlcNAc PF11397.8 RLN93029.1 - 6e-49 167.4 0.0 1.7e-39 136.3 0.0 2.3 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) GlcNAc PF11397.8 RLN93030.1 - 5.2e-20 72.2 0.7 9.8e-20 71.3 0.5 1.7 1 1 0 1 1 1 1 Glycosyltransferase (GlcNAc) CS PF04969.16 RLN93031.1 - 2.8e-07 31.5 1.2 2.8e-07 31.5 0.2 1.5 2 0 0 2 2 2 1 CS domain RAP-1 PF03085.15 RLN93031.1 - 0.026 14.2 0.1 0.036 13.8 0.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FERM_f0 PF16511.5 RLN93031.1 - 0.055 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM F5_F8_type_C PF00754.25 RLN93032.1 - 0.0035 17.5 0.0 0.0045 17.1 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain PH PF00169.29 RLN93033.1 - 1.2e-10 41.9 0.0 2.5e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN93033.1 - 0.029 14.8 0.0 0.029 14.8 0.0 3.1 4 2 0 4 4 4 0 Pleckstrin homology domain PHD PF00628.29 RLN93034.1 - 4.6e-07 29.6 7.4 8.4e-07 28.8 7.4 1.4 1 0 0 1 1 1 1 PHD-finger Forkhead PF00250.18 RLN93034.1 - 0.0074 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain zf-HC5HC2H PF13771.6 RLN93034.1 - 0.011 16.0 2.4 0.021 15.1 2.4 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Elicitin PF00964.17 RLN93035.1 - 1.5e-21 76.2 1.0 2.7e-21 75.4 1.0 1.4 1 0 0 1 1 1 1 Elicitin zf-RanBP PF00641.18 RLN93036.1 - 0.0025 17.1 3.2 0.0039 16.5 3.2 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zinc_ribbon_2 PF13240.6 RLN93036.1 - 0.028 14.2 1.9 0.051 13.3 1.9 1.4 1 0 0 1 1 1 0 zinc-ribbon domain TFIIF_alpha PF05793.12 RLN93036.1 - 0.064 11.8 8.9 0.064 11.8 8.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AP3D1 PF06375.11 RLN93036.1 - 0.066 13.4 11.8 0.084 13.1 11.8 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 TMEM51 PF15345.6 RLN93036.1 - 0.62 9.9 4.6 0.79 9.5 4.6 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DUF3597 PF12200.8 RLN93036.1 - 0.7 10.4 6.8 1.4 9.5 6.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3597) GET2 PF08690.10 RLN93036.1 - 0.71 9.5 5.8 0.8 9.3 5.8 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 FAM176 PF14851.6 RLN93036.1 - 3.1 7.5 5.4 4 7.1 5.4 1.2 1 0 0 1 1 1 0 FAM176 family NPR3 PF03666.13 RLN93036.1 - 3.3 6.4 7.7 3.5 6.3 7.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Rtf2 PF04641.12 RLN93036.1 - 5.1 6.4 12.7 7.1 5.9 12.7 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3464 PF11947.8 RLN93036.1 - 9.2 6.0 9.1 14 5.4 9.1 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 ABC_tran PF00005.27 RLN93037.1 - 2.2e-41 141.6 0.0 4.8e-21 75.7 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN93037.1 - 4.8e-18 66.0 1.4 1.8e-05 24.7 0.1 4.4 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RLN93037.1 - 1.6e-10 40.8 3.5 0.004 16.6 0.0 4.6 5 0 0 5 5 4 2 RecF/RecN/SMC N terminal domain NACHT PF05729.12 RLN93037.1 - 1.2e-05 25.2 0.0 0.11 12.4 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 RLN93037.1 - 1.7e-05 25.3 0.4 0.063 13.7 0.0 3.7 3 0 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.23 RLN93037.1 - 2.2e-05 24.5 0.1 0.064 13.3 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RLN93037.1 - 2.7e-05 24.1 0.0 0.052 13.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 RLN93037.1 - 4.2e-05 23.2 0.1 0.26 11.1 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN93037.1 - 6.3e-05 23.3 0.3 0.48 10.7 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RLN93037.1 - 0.00011 22.8 0.0 0.67 10.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 RLN93037.1 - 0.00011 22.5 0.0 0.57 10.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 RLN93037.1 - 0.00019 20.5 1.1 0.1 11.6 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 RLN93037.1 - 0.00024 21.3 0.0 1.2 9.4 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 RLN93037.1 - 0.00027 20.7 0.1 0.81 9.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 RLN93037.1 - 0.0003 21.2 0.1 0.94 9.9 0.0 3.3 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 RLN93037.1 - 0.0005 20.2 0.0 0.27 11.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RLN93037.1 - 0.00066 20.2 0.0 2.2 8.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain CLASP_N PF12348.8 RLN93037.1 - 0.0013 18.3 1.2 0.0061 16.2 1.0 2.1 1 1 1 2 2 2 1 CLASP N terminal NB-ARC PF00931.22 RLN93037.1 - 0.0028 16.9 0.2 1.8 7.7 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain DUF815 PF05673.13 RLN93037.1 - 0.0034 16.6 0.1 0.22 10.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 RLN93037.1 - 0.0057 16.4 0.1 5.4 6.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 RLN93037.1 - 0.0058 16.4 0.0 5.3 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 RLN93037.1 - 0.0059 16.6 0.0 7.7 6.6 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 RLN93037.1 - 0.008 15.8 0.1 1.5 8.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 RLN93037.1 - 0.0098 16.0 4.8 0.037 14.1 0.0 3.2 4 0 0 4 4 2 1 Helicase HerA, central domain RNA_helicase PF00910.22 RLN93037.1 - 0.0099 16.3 0.0 6.3 7.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ATP-synt_ab PF00006.25 RLN93037.1 - 0.011 15.4 0.0 0.62 9.7 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain UME PF08064.13 RLN93037.1 - 0.011 15.6 3.5 3.3 7.7 0.1 2.9 1 1 1 2 2 2 0 UME (NUC010) domain Thymidylate_kin PF02223.17 RLN93037.1 - 0.015 15.0 1.4 12 5.5 0.0 3.4 3 0 0 3 3 3 0 Thymidylate kinase HEAT PF02985.22 RLN93037.1 - 0.023 14.9 0.3 34 5.1 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat PduV-EutP PF10662.9 RLN93037.1 - 0.027 14.2 0.1 5.4 6.7 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 RLN93037.1 - 0.031 13.8 0.0 6.6 6.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 RLN93037.1 - 0.035 14.1 0.3 11 6.1 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_pol PF00940.19 RLN93037.1 - 0.059 12.2 0.1 0.096 11.5 0.1 1.3 1 0 0 1 1 1 0 DNA-dependent RNA polymerase DUF3584 PF12128.8 RLN93037.1 - 0.085 10.4 2.2 4.2 4.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) HEAT_EZ PF13513.6 RLN93037.1 - 0.09 13.3 4.5 2.6 8.6 0.3 4.4 4 0 0 4 4 3 0 HEAT-like repeat Arf PF00025.21 RLN93037.1 - 0.1 12.1 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.19 RLN93037.1 - 0.11 12.1 0.5 7.7 6.1 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 RLN93037.1 - 0.11 12.2 0.3 12 5.6 0.0 3.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 RLN93037.1 - 0.13 12.3 0.0 0.43 10.6 0.0 1.9 1 0 0 1 1 1 0 Dynamin family 4HB PF17947.1 RLN93037.1 - 0.17 12.0 0.4 0.97 9.5 0.0 2.5 3 0 0 3 3 1 0 Four helical bundle domain MobB PF03205.14 RLN93037.1 - 0.3 11.0 1.4 16 5.4 0.0 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.6 RLN93037.1 - 0.36 11.3 6.7 9.9 6.6 0.1 4.2 4 0 0 4 4 4 0 AAA domain NTPase_1 PF03266.15 RLN93037.1 - 1 9.3 3.6 14 5.5 0.1 2.9 3 0 0 3 3 2 0 NTPase DUF104 PF01954.16 RLN93038.1 - 0.054 13.9 0.0 0.079 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF104 Trypsin PF00089.26 RLN93039.1 - 2e-46 158.6 2.4 2.5e-46 158.3 2.4 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 RLN93039.1 - 1.4e-07 32.5 0.7 2.3e-07 31.8 0.4 1.5 1 1 1 2 2 2 1 Trypsin-like peptidase domain DUF316 PF03761.15 RLN93039.1 - 0.007 16.0 0.0 0.24 10.9 0.0 2.4 1 1 2 3 3 3 1 Chymotrypsin family Peptidase-S1 DUF4148 PF13663.6 RLN93039.1 - 0.56 10.4 3.6 0.5 10.6 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) adh_short PF00106.25 RLN93041.1 - 8.6e-73 244.0 6.1 5.3e-38 130.4 1.2 4.5 2 2 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN93041.1 - 2.6e-68 230.1 7.4 1.1e-33 116.8 0.2 4.2 3 1 0 3 3 3 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN93041.1 - 3.4e-09 36.9 1.0 3.6e-05 23.8 0.3 2.8 2 0 0 2 2 2 2 KR domain Ank_4 PF13637.6 RLN93041.1 - 0.015 15.9 0.2 0.08 13.5 0.0 2.4 2 1 0 2 2 2 0 Ankyrin repeats (many copies) IQ PF00612.27 RLN93041.1 - 0.023 14.4 4.2 0.13 12.1 4.2 2.5 1 0 0 1 1 1 0 IQ calmodulin-binding motif Ank_2 PF12796.7 RLN93041.1 - 0.054 14.1 0.1 0.19 12.4 0.1 1.9 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.30 RLN93041.1 - 0.1 13.1 0.0 0.37 11.3 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeat Shikimate_DH PF01488.20 RLN93041.1 - 0.11 12.6 0.5 1.7 8.7 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Peptidase_M15_4 PF13539.6 RLN93041.1 - 0.11 13.0 0.4 17 6.0 0.0 3.4 4 0 0 4 4 4 0 D-alanyl-D-alanine carboxypeptidase GCP_N_terminal PF17681.1 RLN93041.1 - 0.42 10.2 5.2 2.9 7.4 0.5 3.1 3 0 0 3 3 3 0 Gamma tubulin complex component N-terminal adh_short_C2 PF13561.6 RLN93042.1 - 1.8e-38 132.4 0.2 2.6e-38 131.9 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RLN93042.1 - 5.3e-37 127.2 0.1 7.9e-37 126.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RLN93042.1 - 0.0019 18.2 0.3 0.0045 16.9 0.3 1.7 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 RLN93042.1 - 0.028 13.8 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 RLN93042.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FeS PF04060.13 RLN93042.1 - 0.51 10.0 2.2 0.57 9.9 0.1 2.1 2 0 0 2 2 2 0 Putative Fe-S cluster adh_short PF00106.25 RLN93043.1 - 4e-43 147.2 0.5 5.5e-43 146.7 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN93043.1 - 8.9e-43 146.5 1.5 1.2e-42 146.1 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN93043.1 - 8e-06 25.9 0.1 1.5e-05 24.9 0.1 1.5 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 RLN93043.1 - 0.074 13.3 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 RLN93043.1 - 0.084 12.9 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.10 RLN93043.1 - 0.18 11.1 0.0 0.37 10.1 0.0 1.5 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Peroxidase_2 PF01328.17 RLN93044.1 - 2.4e-56 191.2 0.0 3.2e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Peroxidase_2 PF01328.17 RLN93045.1 - 1.9e-52 178.5 0.0 2.3e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 DUF2428 PF10350.9 RLN93046.1 - 3.6e-52 177.3 0.3 1.8e-51 175.0 0.0 2.5 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) Haem_oxygenas_2 PF14518.6 RLN93046.1 - 0.024 14.4 0.0 0.075 12.8 0.0 1.9 1 0 0 1 1 1 0 Iron-containing redox enzyme DUF1843 PF08898.10 RLN93046.1 - 0.089 13.3 1.5 1.9e+02 2.7 0.0 5.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) HEAT PF02985.22 RLN93046.1 - 0.38 11.1 6.2 4.4 7.8 0.1 5.0 4 0 0 4 4 4 0 HEAT repeat betaPIX_CC PF16523.5 RLN93047.1 - 0.011 15.6 0.2 0.032 14.1 0.2 1.8 1 0 0 1 1 1 0 betaPIX coiled coil DUF4202 PF13875.6 RLN93047.1 - 0.024 14.5 0.1 0.06 13.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) NEMO PF11577.8 RLN93047.1 - 0.032 14.2 2.8 0.097 12.7 2.8 1.8 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO CENP-Q PF13094.6 RLN93047.1 - 0.15 12.2 13.0 1.9 8.7 3.4 2.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FliJ PF02050.16 RLN93047.1 - 0.18 12.0 19.4 0.18 12.0 8.2 2.6 2 1 0 2 2 2 0 Flagellar FliJ protein TMF_DNA_bd PF12329.8 RLN93047.1 - 0.24 11.4 5.2 23 5.1 0.0 3.5 2 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF465 PF04325.13 RLN93047.1 - 0.31 11.1 2.0 2.6 8.1 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF465) DUF1192 PF06698.11 RLN93047.1 - 0.33 11.1 2.7 8.7 6.5 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF3450 PF11932.8 RLN93047.1 - 0.59 9.4 19.8 0.48 9.7 4.6 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF3450) PDE4_UCR PF18100.1 RLN93047.1 - 0.95 10.1 5.9 0.19 12.4 0.5 2.3 2 0 0 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) EzrA PF06160.12 RLN93047.1 - 2.5 6.2 8.4 0.18 10.0 0.6 2.3 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA PTPA PF03095.15 RLN93047.1 - 4.2 6.7 5.0 11 5.4 1.4 2.1 1 1 1 2 2 2 0 Phosphotyrosyl phosphate activator (PTPA) protein DUF2205 PF10224.9 RLN93047.1 - 6.1 6.9 7.4 0.76 9.8 0.9 2.6 3 1 0 3 3 3 0 Short coiled-coil protein TraG_N PF07916.11 RLN93048.1 - 0.085 11.7 4.3 0.13 11.1 4.3 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Prominin PF05478.11 RLN93048.1 - 0.78 7.6 11.3 1.7 6.5 11.3 1.5 1 0 0 1 1 1 0 Prominin Phasin PF05597.11 RLN93048.1 - 9 6.3 25.2 6.6 6.7 3.9 3.6 3 1 1 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4203 PF13886.6 RLN93049.1 - 5.9e-39 133.8 33.5 5.9e-39 133.8 33.5 3.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4203) EamA PF00892.20 RLN93049.1 - 2.1e-09 37.7 8.5 2.1e-09 37.7 8.5 4.7 4 2 1 5 5 5 2 EamA-like transporter family G_path_suppress PF15991.5 RLN93049.1 - 2.5 8.2 14.0 3.7 7.6 14.0 1.1 1 0 0 1 1 1 0 G-protein pathway suppressor DUF4203 PF13886.6 RLN93050.1 - 7.6e-47 159.6 23.3 1.1e-46 159.1 23.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Glyco_trans_4_2 PF13477.6 RLN93050.1 - 0.015 15.4 0.1 0.029 14.4 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like DUF308 PF03729.13 RLN93050.1 - 0.53 10.6 30.1 0.26 11.7 6.1 4.4 1 1 4 5 5 5 0 Short repeat of unknown function (DUF308) Peptidase_S41 PF03572.18 RLN93051.1 - 0.048 13.2 0.3 0.12 11.9 0.3 1.6 1 0 0 1 1 1 0 Peptidase family S41 GoLoco PF02188.17 RLN93051.1 - 0.13 11.8 3.2 0.2 11.2 1.5 2.3 2 0 0 2 2 2 0 GoLoco motif Dzip-like_N PF13815.6 RLN93052.1 - 0.00092 19.2 1.4 0.00097 19.1 0.1 1.7 2 0 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal EF-hand_6 PF13405.6 RLN93053.1 - 6e-28 94.4 6.5 9.4e-05 22.0 0.1 9.0 8 0 0 8 8 8 7 EF-hand domain EF-hand_1 PF00036.32 RLN93053.1 - 6.9e-28 94.1 2.6 7.4e-06 25.2 0.2 9.1 8 0 0 8 8 8 6 EF hand EF-hand_7 PF13499.6 RLN93053.1 - 2.2e-27 95.3 0.9 8.7e-06 26.1 0.0 6.8 5 1 1 6 6 6 6 EF-hand domain pair EF-hand_8 PF13833.6 RLN93053.1 - 2e-17 62.8 10.1 0.00073 19.3 0.0 8.0 8 1 1 9 9 9 4 EF-hand domain pair EF-hand_5 PF13202.6 RLN93053.1 - 1e-09 37.4 16.0 0.0003 20.1 0.1 7.8 9 0 0 9 9 9 3 EF hand EF-hand_4 PF12763.7 RLN93053.1 - 0.0055 16.6 0.3 0.045 13.7 0.0 2.6 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand IQ PF00612.27 RLN93053.1 - 0.0058 16.3 4.1 0.32 10.9 0.1 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif SPARC_Ca_bdg PF10591.9 RLN93053.1 - 0.016 15.5 9.4 0.84 10.0 0.0 5.6 6 2 0 6 6 6 0 Secreted protein acidic and rich in cysteine Ca binding region VCBS PF13517.6 RLN93053.1 - 0.073 13.7 0.0 3 8.5 0.0 3.1 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella CHZ PF09649.10 RLN93054.1 - 4.6 6.8 6.2 7 6.2 4.5 2.2 1 1 1 2 2 2 0 Histone chaperone domain CHZ MFS_1 PF07690.16 RLN93055.1 - 1.4e-07 30.8 38.0 6.3e-05 22.1 14.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_C78 PF07910.13 RLN93056.1 - 8.3e-42 143.1 0.2 1.4e-41 142.4 0.2 1.3 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 RLN93056.1 - 0.00055 19.4 0.1 0.0014 18.2 0.0 1.7 2 0 0 2 2 2 1 Peptidase family C54 CHAD PF05235.14 RLN93056.1 - 0.013 15.5 0.3 0.024 14.6 0.3 1.4 1 1 0 1 1 1 0 CHAD domain PH PF00169.29 RLN93057.1 - 2e-07 31.5 0.2 1.1e-06 29.1 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 RLN93057.1 - 0.22 12.0 2.5 2 8.9 0.9 2.6 1 1 1 2 2 2 0 Pleckstrin homology domain GETHR PF05671.11 RLN93059.1 - 1.3e-07 30.8 49.9 0.14 11.6 1.3 7.9 2 1 8 10 10 10 10 GETHR pentapeptide repeat (5 copies) PX PF00787.24 RLN93059.1 - 0.15 12.1 0.3 0.56 10.2 0.3 1.9 1 1 0 1 1 1 0 PX domain MHYT PF03707.16 RLN93059.1 - 3.9 7.7 5.0 5 7.4 0.7 2.6 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Macoilin PF09726.9 RLN93059.1 - 5.9 5.3 11.8 8.5 4.8 11.8 1.1 1 0 0 1 1 1 0 Macoilin family Sulfatase PF00884.23 RLN93060.1 - 1.8e-29 103.2 0.4 1.6e-28 100.0 0.4 2.2 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 RLN93060.1 - 7e-05 22.6 0.1 0.00091 18.9 0.0 2.2 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 RLN93060.1 - 0.0021 16.7 0.3 0.0038 15.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF229) CitF PF04223.12 RLN93060.1 - 0.092 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) Hydrolase_4 PF12146.8 RLN93061.1 - 1e-13 51.2 0.3 1.7e-10 40.6 0.2 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN93061.1 - 4.6e-09 36.3 0.2 1.7e-07 31.2 0.2 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN93061.1 - 1.1e-05 26.1 3.3 2.4e-05 25.1 3.3 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 RLN93061.1 - 1.3e-05 24.9 0.0 3.8e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) zf-RanBP PF00641.18 RLN93061.1 - 0.047 13.0 0.2 0.1 12.0 0.2 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Elicitin PF00964.17 RLN93061.1 - 0.054 13.6 0.8 0.11 12.7 0.8 1.5 1 0 0 1 1 1 0 Elicitin PhoPQ_related PF10142.9 RLN93061.1 - 0.064 11.9 0.0 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Arm_vescicular PF18770.1 RLN93063.1 - 0.19 11.7 0.3 0.19 11.7 0.3 1.8 2 0 0 2 2 2 0 Armadillo tether-repeat of vescicular transport factor Ribosomal_L35p PF01632.19 RLN93064.1 - 6.8e-18 64.9 10.1 9.3e-18 64.5 10.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L35 zf-AN1 PF01428.16 RLN93065.1 - 4.9e-20 71.4 39.4 1e-12 48.0 9.7 4.8 4 1 1 5 5 5 2 AN1-like Zinc finger zf-C2H2_4 PF13894.6 RLN93065.1 - 0.00011 22.8 0.9 0.018 15.8 0.1 5.5 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.26 RLN93065.1 - 0.00048 20.4 0.3 0.02 15.3 0.0 4.8 6 0 0 6 6 6 2 Zinc finger, C2H2 type zf-C2H2_9 PF16293.5 RLN93065.1 - 0.025 14.4 4.5 1.2 9.1 0.1 3.4 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) Rad50_zn_hook PF04423.14 RLN93065.1 - 0.063 13.1 3.7 2.3 8.1 0.0 3.6 3 0 0 3 3 3 0 Rad50 zinc hook motif SKA1 PF07160.12 RLN93065.1 - 0.17 11.7 2.3 0.78 9.5 0.5 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 zf-C2H2_6 PF13912.6 RLN93065.1 - 0.24 11.4 12.0 0.3 11.1 0.0 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 RLN93065.1 - 0.55 10.7 0.2 0.55 10.7 0.2 3.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-RRN7 PF11781.8 RLN93065.1 - 5 6.9 16.3 12 5.7 0.1 4.6 5 0 0 5 5 5 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Hist_deacetyl PF00850.19 RLN93067.1 - 1.5e-51 175.7 0.0 2.1e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Glycos_transf_1 PF00534.20 RLN93068.1 - 0.0022 17.5 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RLN93068.1 - 0.0023 18.3 0.0 0.0045 17.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pkinase_Tyr PF07714.17 RLN93069.1 - 1.5e-75 253.8 0.0 7.2e-40 136.9 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 RLN93069.1 - 6.6e-74 248.6 0.0 8.7e-39 133.5 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Kinase-like PF14531.6 RLN93069.1 - 1.6e-06 27.7 0.0 0.023 14.0 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 RLN93069.1 - 8.6e-05 22.0 0.0 0.0015 17.9 0.0 2.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Arm PF00514.23 RLN93070.1 - 7.8e-24 82.9 23.0 1.2e-06 28.3 0.1 8.3 9 1 0 9 9 9 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN93070.1 - 1.6e-13 50.8 19.5 3.7e-06 27.3 0.4 5.3 1 1 5 6 6 6 5 HEAT-like repeat HEAT PF02985.22 RLN93070.1 - 1.2e-11 43.8 4.1 0.93 9.9 0.0 7.1 7 0 0 7 7 7 4 HEAT repeat Atx10homo_assoc PF09759.9 RLN93070.1 - 0.0017 18.3 0.1 3.8 7.6 0.0 3.7 3 2 2 5 5 5 2 Spinocerebellar ataxia type 10 protein domain Tox-MPTase3 PF15639.6 RLN93070.1 - 0.0056 16.6 0.2 15 5.4 0.0 3.9 1 1 3 4 4 4 1 Metallopeptidase toxin 3 PfaD_N PF18328.1 RLN93070.1 - 0.0069 16.3 1.6 99 3.0 0.0 4.9 5 0 0 5 5 5 0 Fatty acid synthase subunit PfaD N-terminal domain CAF1C_H4-bd PF12265.8 RLN93070.1 - 0.0094 16.2 0.0 56 4.1 0.0 4.7 6 0 0 6 6 6 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex HEAT_2 PF13646.6 RLN93070.1 - 0.016 15.6 23.8 0.024 15.0 5.3 3.3 1 1 3 4 4 4 0 HEAT repeats eIF-3_zeta PF05091.12 RLN93071.1 - 1.9e-37 129.5 0.2 2.5e-37 129.1 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TEP1_N PF05386.11 RLN93071.1 - 0.43 10.2 0.2 0.43 10.2 0.2 2.1 2 0 0 2 2 2 0 TEP1 N-terminal domain DUF4064 PF13273.6 RLN93072.1 - 0.061 13.6 0.2 0.072 13.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) AAA PF00004.29 RLN93074.1 - 1.3e-40 138.9 0.1 6e-40 136.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RLN93074.1 - 4.8e-10 39.1 0.1 1.1e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 RLN93074.1 - 5e-06 26.7 0.0 2.1e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 RLN93074.1 - 0.00016 22.1 4.4 0.002 18.5 0.2 3.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RLN93074.1 - 0.0019 18.5 0.2 0.02 15.2 0.2 2.4 1 1 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 RLN93074.1 - 0.0031 16.6 0.0 0.0051 15.9 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_5 PF07728.14 RLN93074.1 - 0.0032 17.5 0.2 0.095 12.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RLN93074.1 - 0.0095 15.7 0.1 0.035 13.9 0.0 1.9 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RLN93074.1 - 0.014 15.6 1.1 0.025 14.7 0.0 2.1 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 RLN93074.1 - 0.022 14.5 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 RLN93074.1 - 0.025 14.0 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 RLN93074.1 - 0.044 14.3 0.0 0.044 14.3 0.0 2.6 2 1 0 2 2 1 0 AAA domain AAA_25 PF13481.6 RLN93074.1 - 0.053 13.1 0.1 0.14 11.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RLN93074.1 - 0.058 13.6 2.2 0.064 13.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RLN93074.1 - 0.064 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 RLN93074.1 - 0.08 12.7 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Red1 PF07964.11 RLN93074.1 - 1.3 7.2 8.5 2.1 6.5 8.5 1.3 1 0 0 1 1 1 0 Rec10 / Red1 AA_kinase PF00696.28 RLN93075.1 - 1.7e-26 93.3 0.1 2.8e-26 92.6 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dh PF01118.24 RLN93075.1 - 9.1e-23 81.0 0.0 1.1e-21 77.5 0.0 2.7 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 RLN93075.1 - 0.00051 20.1 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Ras PF00071.22 RLN93076.1 - 3.6e-07 29.9 0.0 6.7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN93076.1 - 2.8e-06 27.5 0.0 5.7e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase CPSase_L_D2 PF02786.17 RLN93077.1 - 6.3e-84 280.7 0.1 9.7e-84 280.1 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 RLN93077.1 - 4.9e-50 168.7 0.0 1e-49 167.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 RLN93077.1 - 2.9e-44 151.1 0.0 3e-42 144.6 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 RLN93077.1 - 5.3e-13 49.4 0.0 3.9e-12 46.6 0.0 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 RLN93077.1 - 1.3e-08 34.6 0.0 2.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 RLN93077.1 - 6e-07 29.2 0.1 1.3e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Peptidase_C26 PF07722.13 RLN93077.1 - 0.00048 20.0 0.2 0.072 12.8 0.1 2.5 1 1 0 2 2 2 1 Peptidase C26 ATPgrasp_Ter PF15632.6 RLN93077.1 - 0.00053 19.7 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 RLN93077.1 - 0.13 12.3 0.0 0.41 10.7 0.0 1.9 1 0 0 1 1 1 0 ATP-grasp domain Actin PF00022.19 RLN93079.1 - 5.3e-137 456.7 0.0 1.7e-136 455.1 0.0 1.6 1 1 0 1 1 1 1 Actin Fibrillarin PF01269.17 RLN93082.1 - 1.5e-15 56.9 0.0 1.6e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin Chorismate_bind PF00425.18 RLN93083.1 - 4.3e-86 288.7 0.0 8.1e-86 287.8 0.0 1.5 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 RLN93083.1 - 1e-37 129.8 0.0 1.8e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 RLN93083.1 - 1.1e-14 54.8 0.0 1e-13 51.7 0.0 2.2 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 RLN93083.1 - 7.7e-14 52.0 0.0 1.3e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 WW PF00397.26 RLN93084.1 - 0.25 11.5 1.6 28 4.9 0.1 2.8 2 0 0 2 2 2 0 WW domain FKBP_C PF00254.28 RLN93085.1 - 1.3e-20 73.5 0.0 2.6e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF853 PF05872.12 RLN93085.1 - 2.2 6.8 13.0 3.3 6.2 13.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Presenilin PF01080.17 RLN93085.1 - 2.6 6.7 19.3 0.12 11.1 12.5 1.9 2 0 0 2 2 2 0 Presenilin NPL PF17800.1 RLN93086.1 - 0.0018 18.8 0.0 0.0023 18.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoplasmin-like domain GFA PF04828.14 RLN93087.1 - 5e-10 39.6 0.6 5e-10 39.6 0.6 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L37e PF01907.19 RLN93087.1 - 0.016 15.4 0.3 0.038 14.1 0.3 1.6 1 0 0 1 1 1 0 Ribosomal protein L37e Bac_luciferase PF00296.20 RLN93088.1 - 0.035 13.5 0.7 0.05 13.0 0.7 1.3 1 1 0 1 1 1 0 Luciferase-like monooxygenase Dynein_C PF18199.1 RLN93089.1 - 1.3e-34 119.8 0.1 1.7e-34 119.5 0.1 1.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 RLN93089.1 - 2.8e-15 56.5 0.0 4.1e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Pkinase PF00069.25 RLN93090.1 - 9.2e-43 146.5 1.3 6.2e-41 140.5 1.3 2.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN93090.1 - 1.4e-17 63.9 1.4 2.7e-16 59.6 1.4 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase DNase_II PF03265.15 RLN93090.1 - 1.4e-13 50.8 0.0 1.1e-10 41.4 0.0 3.3 2 1 0 2 2 2 2 Deoxyribonuclease II Kinesin PF00225.23 RLN93092.1 - 6.2e-77 258.7 1.1 9.5e-77 258.1 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RLN93092.1 - 9.3e-25 87.3 0.0 2.7e-24 85.8 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding DUF3246 PF11596.8 RLN93092.1 - 0.35 10.3 2.5 0.83 9.0 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) YlqD PF11068.8 RLN93092.1 - 4.4 7.7 17.4 1.6 9.1 5.1 2.5 2 0 0 2 2 2 0 YlqD protein EF-hand_1 PF00036.32 RLN93093.1 - 2.2e-05 23.7 0.9 4.5e-05 22.7 0.9 1.5 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 RLN93093.1 - 0.00015 21.6 1.0 0.00027 20.7 0.4 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 RLN93093.1 - 0.0051 17.2 0.8 0.016 15.6 0.2 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN93093.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain DUF3972 PF13118.6 RLN93093.1 - 0.081 13.4 0.8 0.081 13.4 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) EF-hand_5 PF13202.6 RLN93093.1 - 0.11 12.0 0.9 0.22 11.1 0.2 1.8 2 0 0 2 2 2 0 EF hand MatP_C PF17414.2 RLN93093.1 - 3.1 8.1 6.2 8.3 6.7 1.3 3.0 2 1 0 2 2 2 0 MatP C-terminal ribbon-helix-helix domain Ras PF00071.22 RLN93094.1 - 0.094 12.3 0.1 0.98 9.0 0.0 2.2 2 0 0 2 2 2 0 Ras family CbiA PF01656.23 RLN93094.1 - 0.1 12.7 0.0 0.27 11.3 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 RLN93094.1 - 0.11 12.0 0.1 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 RLN93094.1 - 0.22 10.4 0.0 0.37 9.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain MFS_1 PF07690.16 RLN93095.1 - 2e-13 50.0 13.5 1.1e-09 37.7 1.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RLN93095.1 - 0.0017 17.0 0.6 0.0017 17.0 0.6 2.3 2 1 0 2 2 2 1 MFS/sugar transport protein NQR2_RnfD_RnfE PF03116.15 RLN93095.1 - 0.02 14.4 2.2 0.029 13.8 2.2 1.3 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family DUF347 PF03988.12 RLN93095.1 - 0.42 10.8 0.1 0.42 10.8 0.1 2.9 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) Kinesin PF00225.23 RLN93096.1 - 1.3e-78 264.3 1.0 1.3e-78 264.3 1.0 3.2 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 RLN93096.1 - 7.5e-47 159.0 0.0 2.5e-46 157.3 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding Ank_2 PF12796.7 RLN93097.1 - 2.2e-16 60.2 0.0 3.4e-05 24.3 0.0 4.6 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN93097.1 - 3.3e-13 49.8 3.9 0.019 15.5 0.1 7.2 7 2 2 9 9 9 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN93097.1 - 3.3e-12 46.4 5.2 0.06 13.7 0.0 8.5 5 2 4 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN93097.1 - 3.9e-09 36.0 0.4 1.9 9.3 0.0 8.2 10 0 0 10 10 10 1 Ankyrin repeat DUF249 PF03158.13 RLN93097.1 - 0.001 18.9 0.1 0.37 10.5 0.0 2.6 2 1 1 3 3 3 2 Multigene family 530 protein UDPGT PF00201.18 RLN93099.1 - 0.059 12.2 0.1 0.082 11.7 0.1 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Pkinase PF00069.25 RLN93100.1 - 3.4e-36 125.0 0.0 4.9e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN93100.1 - 4.9e-22 78.5 0.0 7.2e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN93100.1 - 0.00014 20.8 0.1 0.00017 20.5 0.1 1.4 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN93100.1 - 0.029 14.3 0.1 0.073 13.0 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 RLN93100.1 - 0.035 13.4 0.1 0.053 12.8 0.1 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 RLN93100.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RLN93100.1 - 0.17 11.5 0.0 0.45 10.1 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.11 RLN93100.1 - 0.17 10.9 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Prominin PF05478.11 RLN93101.1 - 0.00068 17.7 0.0 0.00068 17.7 0.0 3.2 3 1 0 3 3 3 2 Prominin Claudin_3 PF06653.11 RLN93101.1 - 5 7.1 11.8 0.37 10.7 3.1 2.9 3 0 0 3 3 3 0 Tight junction protein, Claudin-like TP_methylase PF00590.20 RLN93102.1 - 7.8e-22 78.3 0.0 1e-21 77.9 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Fra10Ac1 PF09725.9 RLN93103.1 - 3.9e-44 149.7 1.6 7.1e-44 148.9 1.6 1.4 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 P63C PF10546.9 RLN93103.1 - 0.052 14.1 2.0 0.13 12.9 0.3 2.3 2 0 0 2 2 2 0 P63C domain LRIF1 PF15741.5 RLN93103.1 - 0.067 11.7 2.8 0.1 11.1 2.8 1.2 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 DUF755 PF05501.11 RLN93103.1 - 0.094 13.0 10.2 0.23 11.7 10.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) ABC_tran PF00005.27 RLN93104.1 - 2e-31 109.3 0.0 3.2e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 RLN93104.1 - 3.5e-18 65.8 24.1 3.5e-18 65.8 24.1 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 RLN93104.1 - 1e-07 32.1 0.1 5e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RLN93104.1 - 0.0014 18.1 0.1 0.18 11.2 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 RLN93104.1 - 0.049 13.9 0.0 0.34 11.2 0.0 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 RLN93104.1 - 0.16 12.5 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 RLN93104.1 - 1.6 8.0 20.6 0.34 10.1 15.6 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein BTB_2 PF02214.22 RLN93105.1 - 1.4e-17 63.8 0.0 3.3e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Asp_Arg_Hydrox PF05118.15 RLN93106.1 - 9.3e-36 123.0 0.0 1.6e-35 122.2 0.0 1.4 1 1 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Prothymosin PF03247.14 RLN93107.1 - 0.87 10.1 19.4 0.29 11.6 16.4 1.7 2 0 0 2 2 2 0 Prothymosin/parathymosin family PspA_IM30 PF04012.12 RLN93107.1 - 1.4 8.4 16.1 0.094 12.3 10.6 1.8 2 0 0 2 2 2 0 PspA/IM30 family TUSC2 PF15000.6 RLN93108.1 - 3.4 8.0 5.5 28 5.0 0.5 2.5 2 0 0 2 2 2 0 Tumour suppressor candidate 2 PseudoU_synth_2 PF00849.22 RLN93109.1 - 1.2e-27 96.9 0.0 2.9e-27 95.7 0.0 1.7 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ank_2 PF12796.7 RLN93110.1 - 4.8e-49 164.9 16.1 2.2e-12 47.4 0.5 4.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN93110.1 - 2.4e-30 104.5 0.2 6.8e-09 36.1 0.0 5.6 3 2 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN93110.1 - 7.7e-30 99.6 0.4 0.0053 17.2 0.0 7.5 7 0 0 7 7 7 7 Ankyrin repeat Ank PF00023.30 RLN93110.1 - 1.1e-27 95.2 2.2 0.00059 20.2 0.0 7.4 6 1 1 7 7 7 7 Ankyrin repeat Ank_5 PF13857.6 RLN93110.1 - 4.3e-24 84.3 3.4 1.6e-05 25.1 0.0 6.2 2 2 4 6 6 6 5 Ankyrin repeats (many copies) TPR_2 PF07719.17 RLN93110.1 - 1.7e-07 30.8 7.7 0.003 17.6 0.3 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN93110.1 - 6.6e-06 25.7 8.4 0.015 15.1 0.4 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN93110.1 - 0.0018 17.9 1.6 0.0054 16.4 1.6 1.9 1 0 0 1 1 1 1 TPR repeat TPR_19 PF14559.6 RLN93110.1 - 0.013 16.0 2.9 0.013 16.0 2.9 3.1 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN93110.1 - 0.017 15.4 4.9 0.92 9.8 0.1 3.2 1 1 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN93110.1 - 0.039 14.2 2.3 0.1 12.8 0.9 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 RLN93110.1 - 0.36 11.0 7.4 0.31 11.2 2.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN93110.1 - 0.51 11.0 12.1 0.26 11.9 2.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Glyoxalase_6 PF18029.1 RLN93110.1 - 2.7 8.8 5.7 0.56 11.0 0.7 2.6 3 2 0 3 3 1 0 Glyoxalase-like domain TPR_14 PF13428.6 RLN93110.1 - 3 8.9 7.7 7.4 7.7 0.3 3.9 3 0 0 3 3 2 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 RLN93111.1 - 1.1e-70 238.1 0.0 1.3e-70 237.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FHA PF00498.26 RLN93112.1 - 3.2e-16 59.4 0.0 5.8e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RLN93112.1 - 2.4e-07 31.0 0.0 1.1e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain DUF1192 PF06698.11 RLN93112.1 - 0.0092 16.0 1.6 0.0092 16.0 1.6 4.3 5 0 0 5 5 5 1 Protein of unknown function (DUF1192) MAD PF05557.13 RLN93113.1 - 0.0014 17.1 1.7 0.0017 16.8 1.7 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein E2R135 PF11570.8 RLN93113.1 - 0.0092 16.3 0.0 0.018 15.3 0.0 1.5 2 0 0 2 2 2 1 Coiled-coil receptor-binding R-domain of colicin E2 DUF2353 PF09789.9 RLN93113.1 - 0.034 13.5 1.0 0.039 13.3 1.0 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) HAUS-augmin3 PF14932.6 RLN93113.1 - 0.035 13.7 0.7 0.046 13.3 0.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ADIP PF11559.8 RLN93113.1 - 0.035 14.2 1.3 0.059 13.5 1.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding PhaP_Bmeg PF09602.10 RLN93113.1 - 0.039 13.9 0.3 0.057 13.4 0.3 1.2 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Cortex-I_coil PF09304.10 RLN93113.1 - 0.056 13.7 0.7 0.056 13.7 0.7 1.6 2 0 0 2 2 2 0 Cortexillin I, coiled coil DUF4140 PF13600.6 RLN93113.1 - 0.067 13.6 1.9 0.089 13.2 1.9 1.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.11 RLN93113.1 - 0.073 11.9 0.3 0.076 11.9 0.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein JIP_LZII PF16471.5 RLN93113.1 - 0.084 13.1 1.9 0.1 12.8 0.5 1.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II GTP-bdg_M PF16360.5 RLN93113.1 - 0.28 11.8 5.4 0.6 10.7 2.1 2.1 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region PNGaseA PF12222.8 RLN93114.1 - 1.3e-88 297.8 1.4 4e-88 296.2 1.4 1.7 1 1 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A CBM_1 PF00734.18 RLN93114.1 - 0.00016 21.5 4.5 0.00016 21.5 4.5 4.6 4 0 0 4 4 4 2 Fungal cellulose binding domain Toxin_7 PF05980.12 RLN93114.1 - 2.4 8.5 5.8 1.6 9.0 0.4 2.7 2 0 0 2 2 2 0 Toxin 7 Myb_DNA-binding PF00249.31 RLN93115.1 - 2.8e-05 24.2 0.1 5.6e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2559 PF10832.8 RLN93115.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2559) Nup_retrotrp_bd PF10599.9 RLN93115.1 - 1.6 9.5 8.3 0.63 10.7 4.8 2.3 2 1 0 2 2 2 0 Retro-transposon transporting motif Myb_DNA-binding PF00249.31 RLN93116.1 - 2.7e-05 24.3 0.1 5.2e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2559 PF10832.8 RLN93116.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2559) Nup_retrotrp_bd PF10599.9 RLN93116.1 - 0.2 12.3 5.1 0.72 10.5 5.1 2.0 1 1 0 1 1 1 0 Retro-transposon transporting motif zf-UBR PF02207.20 RLN93117.1 - 1.9e-17 63.2 15.9 1.9e-17 63.2 15.9 2.9 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Exo_endo_phos PF03372.23 RLN93118.1 - 0.00061 19.4 0.0 0.0022 17.5 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos PF03372.23 RLN93119.1 - 0.00061 19.4 0.0 0.0022 17.5 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ELO PF01151.18 RLN93122.1 - 2.9e-41 141.7 14.2 3.4e-41 141.4 14.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CCSMST1 PF15013.6 RLN93122.1 - 0.11 12.7 1.7 3.2 8.0 0.1 2.4 1 1 1 2 2 2 0 CCSMST1 family DASH_Hsk3 PF08227.11 RLN93123.1 - 0.059 13.7 0.7 0.12 12.8 0.3 1.6 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like ANAPC10 PF03256.16 RLN93124.1 - 5.1e-61 205.6 0.3 6e-60 202.1 0.3 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) PITH PF06201.13 RLN93124.1 - 0.16 12.2 0.0 0.57 10.4 0.0 1.8 1 1 1 2 2 2 0 PITH domain Pkinase_Tyr PF07714.17 RLN93125.1 - 2e-13 50.2 0.0 3e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN93125.1 - 6.6e-05 22.4 0.0 9.6e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain FAT PF02259.23 RLN93126.1 - 1.1e-32 113.7 7.2 5.6e-31 108.0 4.8 3.1 2 1 0 2 2 2 1 FAT domain DUF3385 PF11865.8 RLN93126.1 - 4.5e-26 91.7 0.7 3.4e-20 72.6 0.1 4.3 3 1 1 4 4 4 3 Domain of unknown function (DUF3385) TPR_19 PF14559.6 RLN93126.1 - 1.9e-06 28.3 0.0 0.15 12.5 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat HEAT_EZ PF13513.6 RLN93126.1 - 0.004 17.6 2.4 0.7 10.5 0.1 4.1 3 1 1 4 4 4 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 RLN93126.1 - 0.012 16.2 0.7 0.57 10.8 0.1 2.9 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region SET PF00856.28 RLN93127.1 - 1.7e-12 48.0 7.6 3.8e-12 46.9 1.3 2.4 1 1 1 2 2 2 2 SET domain EAP30 PF04157.16 RLN93127.1 - 0.0024 17.2 0.0 1.6 8.0 0.0 2.4 2 0 0 2 2 2 2 EAP30/Vps36 family MIF4G_like_2 PF09090.11 RLN93127.1 - 0.03 13.8 0.3 0.03 13.8 0.3 1.6 2 0 0 2 2 2 0 MIF4G like DUF1840 PF08895.11 RLN93127.1 - 0.25 11.7 1.1 0.43 10.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) zf-MYND PF01753.18 RLN93127.1 - 1.3 9.2 10.5 0.049 13.7 4.0 2.1 2 0 0 2 2 2 0 MYND finger Peptidase_C69 PF03577.15 RLN93128.1 - 1.8e-54 185.2 0.0 5.7e-54 183.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase family C69 LPMO_10 PF03067.15 RLN93129.1 - 1.5e-09 38.8 0.0 2.8e-09 37.9 0.0 1.5 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 RLN93129.1 - 0.0035 17.3 0.1 0.12 12.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 MSP1a PF11670.8 RLN93129.1 - 1.8 7.8 8.0 4 6.7 8.0 1.5 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) DEAD PF00270.29 RLN93130.1 - 3.6e-27 95.3 0.0 9e-27 94.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN93130.1 - 1.3e-22 80.2 0.0 2.4e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN93130.1 - 0.0074 16.3 0.0 0.031 14.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RLN93130.1 - 0.017 15.4 0.0 0.05 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 RLN93130.1 - 0.031 14.0 0.1 0.078 12.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain Helicase_C_2 PF13307.6 RLN93130.1 - 0.088 13.0 0.0 0.23 11.6 0.0 1.6 2 0 0 2 2 2 0 Helicase C-terminal domain FliT PF05400.13 RLN93130.1 - 8.6 7.3 8.3 19 6.2 0.6 3.8 3 0 0 3 3 3 0 Flagellar protein FliT KIX_2 PF16987.5 RLN93131.1 - 0.067 13.2 0.1 0.13 12.3 0.1 1.5 1 1 0 1 1 1 0 KIX domain KIX_2 PF16987.5 RLN93132.1 - 0.0061 16.5 0.3 0.013 15.5 0.2 1.5 1 1 0 1 1 1 1 KIX domain HTH_30 PF13556.6 RLN93132.1 - 0.078 12.8 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain KIX_2 PF16987.5 RLN93133.1 - 0.00025 21.0 0.1 0.00048 20.1 0.1 1.6 1 1 0 1 1 1 1 KIX domain Totivirus_coat PF05518.11 RLN93134.1 - 0.096 10.7 1.4 0.12 10.4 1.4 1.1 1 0 0 1 1 1 0 Totivirus coat protein KIX_2 PF16987.5 RLN93134.1 - 0.11 12.5 0.3 0.26 11.3 0.1 1.8 1 1 1 2 2 2 0 KIX domain DUF3720 PF12517.8 RLN93134.1 - 1 10.3 5.1 1.6 9.7 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) WD40 PF00400.32 RLN93135.1 - 2e-64 212.0 14.1 3.5e-08 34.0 0.1 8.5 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN93135.1 - 1e-20 73.8 0.9 0.0042 17.4 0.0 6.7 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RLN93135.1 - 6.4e-10 38.8 2.5 9e-05 21.9 0.3 4.9 2 2 2 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 RLN93135.1 - 1.1e-08 34.4 4.1 0.035 13.1 0.0 4.8 1 1 2 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RLN93135.1 - 2.3e-06 26.5 6.9 0.37 9.4 0.0 5.4 2 2 4 6 6 6 3 Nucleoporin Nup120/160 DUF5570 PF17731.1 RLN93135.1 - 0.00054 20.0 4.8 0.16 12.0 0.0 4.1 1 1 4 5 5 5 1 Family of unknown function (DUF5570) WD40_3 PF15911.5 RLN93135.1 - 0.0021 18.0 0.4 6.9 6.8 0.0 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat CEP19 PF14933.6 RLN93135.1 - 0.12 12.7 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 CEP19-like protein PKD PF00801.20 RLN93135.1 - 0.14 12.0 0.6 72 3.3 0.2 3.4 3 0 0 3 3 3 0 PKD domain Tom7 PF08038.12 RLN93136.1 - 1.8e-07 30.7 0.4 3.2e-07 29.9 0.4 1.5 1 0 0 1 1 1 1 TOM7 family Cpn60_TCP1 PF00118.24 RLN93137.1 - 2.6e-141 471.6 12.9 2.9e-141 471.5 12.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Trp_oprn_chp PF09534.10 RLN93138.1 - 0.00095 19.0 3.2 0.00095 19.0 3.2 2.1 2 0 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Amnionless PF14828.6 RLN93138.1 - 0.025 13.4 0.1 0.031 13.1 0.1 1.2 1 0 0 1 1 1 0 Amnionless DUF4131 PF13567.6 RLN93138.1 - 0.073 12.7 0.0 4.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4366 PF14283.6 RLN93138.1 - 0.52 10.3 4.5 1.8 8.6 4.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) PalH PF08733.10 RLN93138.1 - 1.6 7.7 6.1 1.6 7.7 1.2 2.0 1 1 1 2 2 2 0 PalH/RIM21 His_Phos_1 PF00300.22 RLN93140.1 - 3.7e-50 170.3 0.2 4.5e-50 170.0 0.2 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF4064 PF13273.6 RLN93141.1 - 0.087 13.1 0.1 0.2 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) SBP_bac_5 PF00496.22 RLN93141.1 - 0.14 11.1 0.1 0.18 10.8 0.1 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Hemerythrin PF01814.23 RLN93142.1 - 0.092 13.4 0.1 0.54 10.9 0.0 2.0 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain HSF_DNA-bind PF00447.17 RLN93144.1 - 1.8e-06 28.5 0.1 5.2e-06 27.0 0.0 1.8 2 1 0 2 2 2 1 HSF-type DNA-binding PAP2_C PF14360.6 RLN93145.1 - 3.5e-22 78.7 6.5 3.5e-22 78.7 6.5 2.0 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2_3 PF14378.6 RLN93145.1 - 3e-05 23.8 6.3 5.7e-05 22.9 6.3 1.6 1 1 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 RLN93145.1 - 3.6e-05 23.5 2.2 5.6e-05 22.9 2.2 1.4 1 1 0 1 1 1 1 PAP2 superfamily GPI2 PF06432.11 RLN93145.1 - 1.3 8.4 8.4 0.28 10.6 1.7 2.1 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase BCDHK_Adom3 PF10436.9 RLN93146.1 - 1.8e-26 92.9 0.0 2.6e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 RLN93146.1 - 3.7e-05 24.2 0.0 6.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ank_2 PF12796.7 RLN93147.1 - 1.2e-26 93.1 0.2 2.1e-14 53.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN93147.1 - 1.2e-25 89.6 2.7 2.5e-09 37.5 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN93147.1 - 5e-22 75.6 4.0 0.00013 22.1 0.1 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 RLN93147.1 - 4.4e-20 71.2 9.9 0.00027 21.2 0.4 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 RLN93147.1 - 5.9e-16 58.3 5.1 1.2e-05 25.4 0.0 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) FAD-oxidase_C PF02913.19 RLN93147.1 - 0.085 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain DUF5319 PF17252.2 RLN93148.1 - 0.13 12.5 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5319) DUF3160 PF11369.8 RLN93150.1 - 6.2e-113 378.4 0.0 1.9e-112 376.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3160) Spidroin_MaSp PF11260.8 RLN93150.1 - 0.14 12.5 5.0 0.21 11.9 1.3 2.5 2 0 0 2 2 2 0 Major ampullate spidroin 1 and 2 Peptidase_C26 PF07722.13 RLN93154.1 - 1.5e-19 70.6 0.0 8.6e-18 64.9 0.0 2.2 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 RLN93154.1 - 8.5e-09 35.4 0.0 1.3e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 RLN93154.1 - 0.042 13.7 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 SNO glutamine amidotransferase family GAS PF13851.6 RLN93156.1 - 0.0014 18.1 13.8 0.0014 18.1 13.8 4.2 3 1 1 4 4 4 1 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 RLN93156.1 - 0.086 13.0 0.3 0.086 13.0 0.3 5.3 4 3 2 6 6 6 0 bZIP transcription factor Shugoshin_N PF07558.11 RLN93156.1 - 0.2 11.5 6.0 1.8 8.5 0.3 3.0 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region EspB_PE PF18625.1 RLN93156.1 - 2 9.0 9.9 0.16 12.4 0.8 3.7 3 0 0 3 3 3 0 ESX-1 secreted protein B PE domain DUF948 PF06103.11 RLN93156.1 - 2.7 8.3 7.3 3.2 8.1 0.1 3.8 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) HIP1_clath_bdg PF16515.5 RLN93156.1 - 4 8.1 60.5 1.4 9.6 2.9 6.3 4 2 2 6 6 6 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PITH PF06201.13 RLN93157.1 - 1.7e-24 86.7 0.0 1.7e-13 51.1 0.0 2.1 1 1 1 2 2 2 2 PITH domain DUF1779 PF08680.10 RLN93158.1 - 0.024 14.8 0.6 0.028 14.6 0.6 1.1 1 0 0 1 1 1 0 TATA-box binding YqzE PF14038.6 RLN93158.1 - 0.11 12.5 0.4 0.23 11.5 0.4 1.5 1 0 0 1 1 1 0 YqzE-like protein DUF4337 PF14235.6 RLN93158.1 - 0.24 11.5 4.2 0.28 11.3 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Peptidase_S49_N PF08496.10 RLN93158.1 - 0.48 10.5 5.1 0.65 10.0 5.1 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SAYSvFN PF10260.9 RLN93160.1 - 0.039 13.9 0.3 0.41 10.6 1.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) Mpv17_PMP22 PF04117.12 RLN93164.1 - 6.3e-16 58.3 0.0 1.1e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.12 RLN93165.1 - 1.4e-18 66.8 0.1 2.4e-18 66.1 0.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Flavin_Reduct PF01613.18 RLN93166.1 - 1.5e-16 60.8 0.0 2.1e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain ASH PF15780.5 RLN93167.1 - 2.3e-22 79.0 0.8 0.0022 18.1 0.3 9.0 9 1 0 9 9 9 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 RLN93167.1 - 0.0019 18.0 0.0 16 5.4 0.0 5.9 8 0 0 8 8 8 1 MSP (Major sperm protein) domain PapD-like PF14874.6 RLN93167.1 - 0.043 14.0 0.7 0.93 9.7 0.2 3.4 4 0 0 4 4 4 0 Flagellar-associated PapD-like DapB_C PF05173.14 RLN93168.1 - 5.3e-29 100.7 0.0 1.1e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus Aminotran_1_2 PF00155.21 RLN93168.1 - 1.3e-09 37.8 0.0 3e-09 36.5 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II DapB_N PF01113.20 RLN93168.1 - 3.3e-07 30.5 0.1 1.5e-05 25.1 0.1 2.6 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus CTP_transf_1 PF01148.20 RLN93169.1 - 4.5e-11 43.0 7.4 1.1e-10 41.7 7.4 1.6 1 0 0 1 1 1 1 Cytidylyltransferase family DUF872 PF05915.12 RLN93169.1 - 0.017 15.3 1.5 1.4 9.1 0.1 3.2 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) zf-MYND PF01753.18 RLN93170.1 - 6.1e-10 39.0 19.8 1.1e-09 38.2 19.8 1.5 1 0 0 1 1 1 1 MYND finger DUF3446 PF11928.8 RLN93170.1 - 0.069 13.5 3.6 0.2 12.0 3.6 1.7 1 0 0 1 1 1 0 Early growth response N-terminal domain DUF4611 PF15387.6 RLN93170.1 - 0.54 10.5 3.6 1.3 9.3 3.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) zf-C6H2 PF15801.5 RLN93170.1 - 7.5 6.9 13.9 18 5.8 13.9 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DAGAT PF03982.13 RLN93171.1 - 5.6e-05 22.2 0.0 0.00016 20.7 0.0 1.7 1 1 0 1 1 1 1 Diacylglycerol acyltransferase CTD PF12815.7 RLN93171.1 - 0.14 12.8 0.3 0.27 11.8 0.3 1.4 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 DAGAT PF03982.13 RLN93172.1 - 4.6e-30 104.6 0.0 1.2e-22 80.2 0.1 2.0 2 0 0 2 2 2 2 Diacylglycerol acyltransferase RPA_interact_N PF14766.6 RLN93173.1 - 1.7e-10 40.4 4.5 3.7e-10 39.3 4.5 1.6 1 0 0 1 1 1 1 Replication protein A interacting N-terminal Bcl-2_BAD PF10514.9 RLN93173.1 - 0.15 12.5 3.3 0.11 13.0 1.7 1.6 2 0 0 2 2 2 0 Pro-apoptotic Bcl-2 protein, BAD IML1 PF12257.8 RLN93174.1 - 3.1e-86 289.0 0.0 5.5e-86 288.2 0.0 1.4 1 1 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 Telethonin PF09470.10 RLN93174.1 - 0.039 13.9 0.1 0.083 12.8 0.1 1.5 1 0 0 1 1 1 0 Telethonin protein PBP1_TM PF14812.6 RLN93174.1 - 0.17 12.3 0.1 0.56 10.6 0.1 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UBA_4 PF14555.6 RLN93176.1 - 0.032 14.1 0.0 0.065 13.1 0.0 1.5 2 0 0 2 2 2 0 UBA-like domain NAD_Gly3P_dh_C PF07479.14 RLN93177.1 - 7.4e-40 136.5 0.0 1.3e-39 135.7 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 RLN93177.1 - 1.4e-34 119.4 0.0 1.9e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 RLN93177.1 - 1.5e-08 35.1 0.1 3.5e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 RLN93177.1 - 2.1e-05 24.7 0.0 3.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 RLN93177.1 - 2.2e-05 24.1 0.0 3.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 RLN93177.1 - 0.00033 20.6 0.5 0.00087 19.2 0.5 1.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 RLN93177.1 - 0.0047 16.5 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 RLN93177.1 - 0.01 15.2 0.1 0.16 11.3 0.1 2.3 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 RLN93177.1 - 0.015 15.2 0.1 0.031 14.2 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H-binding AlaDh_PNT_C PF01262.21 RLN93177.1 - 0.03 13.6 0.5 0.062 12.6 0.3 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_transf_4 PF13439.6 RLN93177.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Rossmann-like PF10727.9 RLN93177.1 - 0.15 11.9 2.8 0.53 10.1 2.8 1.9 1 1 0 1 1 1 0 Rossmann-like domain DUF5102 PF17104.5 RLN93178.1 - 0.16 11.9 2.0 0.24 11.4 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) Macro PF01661.21 RLN93179.1 - 3.7e-16 59.2 0.2 5.7e-16 58.6 0.2 1.4 1 1 0 1 1 1 1 Macro domain Mito_carr PF00153.27 RLN93180.1 - 1.6e-48 162.6 7.2 9.1e-16 57.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GSHPx PF00255.19 RLN93181.1 - 5.1e-21 74.3 0.0 8.2e-21 73.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase Ank_2 PF12796.7 RLN93182.1 - 1e-25 90.1 2.5 6.4e-16 58.7 0.6 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN93182.1 - 7.5e-17 61.5 3.8 4.5e-11 43.1 0.6 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN93182.1 - 3.8e-15 55.7 4.5 2.6e-08 34.0 0.6 3.1 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN93182.1 - 5.8e-14 51.8 9.6 1.6e-06 28.2 0.2 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 RLN93182.1 - 1.7e-08 34.1 2.9 0.0053 17.2 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Rax2 PF12768.7 RLN93182.1 - 0.12 11.8 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity VWA_3_C PF18571.1 RLN93182.1 - 0.15 11.9 3.3 1.3 8.9 0.0 3.6 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain Aminotran_1_2 PF00155.21 RLN93183.1 - 1.9e-41 142.5 0.0 2.2e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 RLN93183.1 - 9.8e-05 21.0 0.0 0.00018 20.1 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 RLN93183.1 - 0.0054 15.5 0.1 0.0086 14.9 0.1 1.4 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 RLN93183.1 - 0.026 13.5 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V HSF_DNA-bind PF00447.17 RLN93184.1 - 2.9e-18 66.3 0.3 5.3e-18 65.4 0.3 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Pkinase PF00069.25 RLN93185.1 - 3.5e-43 147.9 0.0 9.2e-29 100.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN93185.1 - 4.1e-43 147.5 0.0 5.8e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN93185.1 - 0.05 12.4 1.1 0.1 11.3 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase PX PF00787.24 RLN93186.1 - 2.8e-07 30.5 0.6 4.7e-06 26.6 0.0 2.8 2 1 0 2 2 2 1 PX domain Vert_HS_TF PF06546.11 RLN93186.1 - 0.38 10.4 6.2 0.34 10.5 0.2 2.2 1 1 0 2 2 2 0 Vertebrate heat shock transcription factor SOBP PF15279.6 RLN93186.1 - 0.92 10.1 8.5 1.7 9.2 8.5 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein NUDIX PF00293.28 RLN93187.1 - 2.2e-06 27.7 0.1 4.3e-06 26.8 0.0 1.5 1 1 1 2 2 2 1 NUDIX domain MRP-L46 PF11788.8 RLN93188.1 - 0.00035 21.3 1.4 0.0024 18.6 0.0 2.1 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 Glyco_hydro_6 PF01341.17 RLN93190.1 - 8.8e-51 173.4 0.6 1.9e-50 172.4 0.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 DUF659 PF04937.15 RLN93190.1 - 9.7e-09 35.3 0.0 3.1e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) zf-BED PF02892.15 RLN93190.1 - 0.0024 17.8 2.0 0.005 16.8 2.0 1.5 1 0 0 1 1 1 1 BED zinc finger DUF3357 PF11837.8 RLN93190.1 - 0.04 14.4 2.7 19 5.8 0.0 4.4 3 1 1 4 4 4 0 Domain of unknown function (DUF3357) Germane PF10646.9 RLN93190.1 - 9.2 7.1 8.2 0.56 11.0 0.1 3.0 2 1 0 2 2 2 0 Sporulation and spore germination Glyco_hydro_6 PF01341.17 RLN93191.1 - 1.7e-50 172.5 1.5 1.7e-50 172.5 1.5 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 6 PAP1 PF08601.10 RLN93191.1 - 0.0046 16.7 14.3 0.008 15.9 14.3 1.4 1 0 0 1 1 1 1 Transcription factor PAP1 TMEM154 PF15102.6 RLN93191.1 - 0.023 14.6 1.4 0.023 14.6 1.4 2.6 1 1 0 2 2 2 0 TMEM154 protein family Presenilin PF01080.17 RLN93191.1 - 0.038 12.8 1.9 0.057 12.2 1.9 1.2 1 0 0 1 1 1 0 Presenilin ABC2_membrane_3 PF12698.7 RLN93191.1 - 0.25 10.4 3.0 0.43 9.6 3.0 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein SOG2 PF10428.9 RLN93191.1 - 0.67 9.1 18.0 0.97 8.6 18.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4366 PF14283.6 RLN93191.1 - 0.8 9.7 7.6 6.3 6.8 7.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Hamartin PF04388.12 RLN93191.1 - 2.4 6.7 14.2 3.3 6.3 14.2 1.1 1 0 0 1 1 1 0 Hamartin protein Macoilin PF09726.9 RLN93191.1 - 6.8 5.1 5.5 9.2 4.7 5.5 1.1 1 0 0 1 1 1 0 Macoilin family Glyco_hydro_6 PF01341.17 RLN93192.1 - 1.9e-14 54.1 0.6 1.2e-12 48.3 0.6 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 6 Gram_pos_anchor PF00746.21 RLN93192.1 - 6 6.9 5.7 1.4 9.0 2.2 1.8 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Dioxygenase_C PF00775.21 RLN93193.1 - 3.5e-07 29.8 0.2 1e-06 28.3 0.1 1.7 2 0 0 2 2 2 1 Dioxygenase PH PF00169.29 RLN93194.1 - 0.0091 16.5 0.0 0.016 15.7 0.0 1.4 1 0 0 1 1 1 1 PH domain GSHPx PF00255.19 RLN93195.1 - 4.1e-36 122.8 0.3 7.3e-36 122.0 0.3 1.4 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 RLN93195.1 - 5.6e-06 26.3 0.2 8.5e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 RLN93195.1 - 0.0066 16.2 0.1 0.027 14.2 0.0 2.0 2 0 0 2 2 2 1 Redoxin GSHPx PF00255.19 RLN93196.1 - 1.4e-37 127.5 1.5 3.2e-37 126.4 1.5 1.6 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 RLN93196.1 - 1.1e-05 25.3 0.1 2.7e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RLN93196.1 - 0.00078 19.2 0.0 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 Redoxin SDA1 PF05285.12 RLN93196.1 - 0.0046 16.4 18.6 0.0046 16.4 18.6 2.1 2 0 0 2 2 2 1 SDA1 Presenilin PF01080.17 RLN93196.1 - 2 7.1 10.7 0.022 13.5 2.6 1.8 2 0 0 2 2 2 0 Presenilin Spore_coat_CotO PF14153.6 RLN93196.1 - 2.1 8.2 37.6 0.031 14.2 20.0 2.3 2 0 0 2 2 2 0 Spore coat protein CotO RR_TM4-6 PF06459.12 RLN93196.1 - 7.6 6.3 30.4 0.48 10.2 17.8 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Pkinase_Tyr PF07714.17 RLN93197.1 - 3.4e-58 197.0 0.0 2.6e-42 144.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN93197.1 - 4.7e-48 163.9 0.0 1e-35 123.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Arm PF00514.23 RLN93197.1 - 2.8e-05 24.0 1.0 0.37 10.9 0.1 4.3 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN93197.1 - 0.0036 17.6 2.0 0.0087 16.4 0.3 2.7 2 0 0 2 2 2 1 HEAT repeats Kinase-like PF14531.6 RLN93197.1 - 0.011 15.1 0.0 0.8 9.0 0.0 2.5 2 0 0 2 2 2 0 Kinase-like HEAT_EZ PF13513.6 RLN93197.1 - 0.036 14.6 1.1 0.22 12.1 0.9 2.5 2 0 0 2 2 2 0 HEAT-like repeat Ebp2 PF05890.12 RLN93198.1 - 6.7e-11 42.3 20.4 7.5e-11 42.1 20.4 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 WW PF00397.26 RLN93199.1 - 1.4e-06 28.3 0.3 4.5e-06 26.6 0.3 2.0 1 0 0 1 1 1 1 WW domain zf-CpG_bind_C PF12269.8 RLN93199.1 - 2.8 7.7 7.2 0.22 11.3 1.8 1.9 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain zf-B_box PF00643.24 RLN93199.1 - 3.7 7.8 24.0 2.6 8.2 7.1 4.5 4 0 0 4 4 4 0 B-box zinc finger Oxidored_FMN PF00724.20 RLN93200.1 - 4.1e-75 253.2 0.0 5.3e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family E1-E2_ATPase PF00122.20 RLN93200.1 - 3.8e-18 65.6 0.0 6.6e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 RLN93200.1 - 8.1e-14 51.1 0.0 1.6e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus ABC_membrane PF00664.23 RLN93201.1 - 1.6e-56 192.0 4.0 2e-56 191.7 4.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN93201.1 - 1.1e-12 48.7 0.0 2e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 RLN93201.1 - 0.00074 19.5 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN93201.1 - 0.0092 15.7 0.1 0.021 14.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN93201.1 - 0.11 12.9 0.1 0.31 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain C2 PF00168.30 RLN93202.1 - 1.8e-62 208.0 0.0 1.2e-11 44.8 0.0 7.6 8 0 0 8 8 8 6 C2 domain FerI PF08151.12 RLN93202.1 - 0.0063 16.6 0.0 0.025 14.7 0.0 2.0 1 0 0 1 1 1 1 FerI (NUC094) domain Ferlin_C PF16165.5 RLN93202.1 - 0.0074 16.2 0.2 0.02 14.9 0.0 1.8 2 0 0 2 2 2 1 Ferlin C-terminus FYVE PF01363.21 RLN93204.1 - 6.6e-12 45.4 12.9 6.6e-12 45.4 12.9 1.7 2 0 0 2 2 2 1 FYVE zinc finger GAF PF01590.26 RLN93204.1 - 8.3e-07 29.7 0.1 2.9e-06 27.9 0.1 1.9 2 0 0 2 2 2 1 GAF domain FYVE_2 PF02318.16 RLN93204.1 - 0.0015 18.7 4.3 0.0015 18.7 4.3 2.1 2 0 0 2 2 2 1 FYVE-type zinc finger PEGSRP PF07623.11 RLN93204.1 - 0.045 13.5 0.1 0.18 11.6 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) Bromodomain PF00439.25 RLN93205.1 - 0.043 13.9 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 Bromodomain DNA_pol_phi PF04931.13 RLN93205.1 - 1.4 6.9 6.5 1.9 6.5 6.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 RLN93205.1 - 5.3 7.5 10.6 6.5 7.2 9.2 2.0 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.32 RLN93206.1 - 5.9e-27 93.4 13.8 3.5e-07 30.8 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Bromodomain PF00439.25 RLN93206.1 - 1.1e-22 79.9 1.4 2.6e-16 59.4 0.4 2.6 2 0 0 2 2 2 2 Bromodomain zf-HC5HC2H PF13771.6 RLN93206.1 - 3.8e-08 33.5 7.0 3.8e-08 33.5 7.0 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 RLN93206.1 - 6.6e-06 26.3 4.5 2.1e-05 24.7 4.5 1.8 1 0 0 1 1 1 1 PHD-zinc-finger like domain TFIIA PF03153.13 RLN93206.1 - 0.0004 20.5 0.3 0.0004 20.5 0.3 4.3 5 0 0 5 5 5 1 Transcription factor IIA, alpha/beta subunit Nup160 PF11715.8 RLN93206.1 - 0.007 15.1 0.2 1.6 7.3 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 RRM_1 PF00076.22 RLN93207.1 - 5.3e-16 58.2 0.0 5.8e-16 58.1 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN93207.1 - 2.7e-05 24.2 0.0 2.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 RLN93207.1 - 0.03 14.3 0.0 0.036 14.1 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif CBM_20 PF00686.19 RLN93208.1 - 1.5e-05 24.8 0.0 0.00071 19.4 0.0 2.0 1 1 0 1 1 1 1 Starch binding domain PK PF00224.21 RLN93209.1 - 2e-143 477.5 1.2 3e-143 476.9 0.3 1.6 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain PK_C PF02887.16 RLN93209.1 - 2.2e-28 98.8 0.2 5.4e-28 97.6 0.2 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 RLN93209.1 - 0.00077 18.7 0.1 0.0018 17.5 0.1 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 RLN93210.1 - 1.6e-72 244.3 1.9 7.7e-72 242.1 0.8 2.0 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain PK_C PF02887.16 RLN93210.1 - 8.3e-31 106.7 1.0 1.8e-30 105.5 1.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 RLN93210.1 - 0.0028 16.8 0.4 0.03 13.5 0.0 2.2 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Staph_opine_DH PF10100.9 RLN93210.1 - 0.045 12.4 0.0 0.062 11.9 0.0 1.1 1 0 0 1 1 1 0 Staphylopine dehydrogenase Ku_PK_bind PF08785.11 RLN93210.1 - 0.18 12.0 0.0 0.4 10.8 0.0 1.7 1 1 0 1 1 1 0 Ku C terminal domain like Cytochrom_B561 PF03188.16 RLN93212.1 - 1.6e-09 38.0 1.0 6.6e-09 36.0 1.1 2.0 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Isochorismatase PF00857.20 RLN93212.1 - 1.2e-05 25.6 0.0 0.00056 20.1 0.0 2.8 1 1 0 1 1 1 1 Isochorismatase family DEDD_Tnp_IS110 PF01548.17 RLN93212.1 - 0.16 11.9 0.1 7.9 6.3 0.0 2.4 1 1 1 2 2 2 0 Transposase Cytochrom_B561 PF03188.16 RLN93213.1 - 8.3e-11 42.2 1.3 1.4e-10 41.4 1.3 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Porin_3 PF01459.22 RLN93213.1 - 0.025 14.0 0.3 0.072 12.5 0.2 1.7 2 0 0 2 2 2 0 Eukaryotic porin ubiquitin PF00240.23 RLN93215.1 - 1e-14 54.0 0.0 3.6e-14 52.3 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Tudor-knot PF11717.8 RLN93215.1 - 0.0036 17.2 0.7 0.0076 16.1 0.7 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MBT PF02820.18 RLN93215.1 - 0.011 16.1 0.2 0.023 15.1 0.2 1.4 1 0 0 1 1 1 0 mbt repeat Ubiquitin_2 PF14560.6 RLN93215.1 - 0.045 14.2 0.0 0.098 13.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD PF11976.8 RLN93215.1 - 0.2 11.5 0.0 0.62 9.9 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like zf-C4H2 PF10146.9 RLN93216.1 - 3e-05 24.4 0.1 0.012 16.0 0.0 2.7 2 0 0 2 2 2 2 Zinc finger-containing protein Cep57_CLD PF14073.6 RLN93216.1 - 0.019 15.0 14.8 0.067 13.2 5.0 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 Fmp27_WPPW PF10359.9 RLN93216.1 - 0.062 12.2 3.1 3.2 6.5 0.1 2.2 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain AAA_23 PF13476.6 RLN93216.1 - 0.67 10.4 6.7 2.2 8.7 5.7 2.1 1 1 0 1 1 1 0 AAA domain Cytochrom_B562 PF07361.11 RLN93216.1 - 3.7 8.3 9.7 1.1 9.9 0.7 3.1 3 0 0 3 3 3 0 Cytochrome b562 DUF1664 PF07889.12 RLN93216.1 - 5.5 7.1 12.7 4.9 7.2 2.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) FapA PF03961.13 RLN93216.1 - 7.3 5.1 8.0 3.1 6.3 0.7 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A SAGA-Tad1 PF12767.7 RLN93217.1 - 1.2e-11 44.8 0.1 1.8e-11 44.2 0.1 1.3 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit LSM PF01423.22 RLN93218.1 - 3e-09 36.5 0.0 8.3e-09 35.0 0.0 1.8 1 1 0 1 1 1 1 LSM domain 7tm_3 PF00003.22 RLN93219.1 - 0.00039 20.2 0.0 0.00043 20.1 0.0 1.0 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF2721 PF11026.8 RLN93219.1 - 0.027 14.3 1.8 0.031 14.2 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) EF-hand_1 PF00036.32 RLN93221.1 - 1.3e-08 33.8 0.1 0.0022 17.4 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RLN93221.1 - 1.3e-08 34.1 0.0 0.00056 19.6 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 RLN93221.1 - 2.4e-06 27.9 0.1 0.0072 16.8 0.0 3.5 2 1 0 2 2 2 2 EF-hand domain pair WW PF00397.26 RLN93221.1 - 2e-05 24.6 4.4 0.013 15.5 0.3 2.9 3 0 0 3 3 3 2 WW domain EF-hand_5 PF13202.6 RLN93221.1 - 0.0053 16.2 0.2 0.55 9.8 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 RLN93221.1 - 0.03 14.2 0.1 4.1 7.3 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain pair IQ PF00612.27 RLN93221.1 - 0.98 9.4 6.5 1.7 8.6 0.5 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif Methyltransf_23 PF13489.6 RLN93222.1 - 1.3e-13 51.1 0.0 2.2e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN93222.1 - 1.7e-13 51.1 0.1 5.3e-13 49.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 RLN93222.1 - 4.6e-13 49.1 0.0 6.1e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 RLN93222.1 - 8.5e-12 45.6 0.0 1.8e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN93222.1 - 3.2e-08 34.2 0.0 6.9e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN93222.1 - 4.4e-06 26.6 0.0 1.1e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN93222.1 - 0.00063 19.1 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 RLN93222.1 - 0.005 15.9 0.0 0.0071 15.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 RLN93222.1 - 0.0066 15.8 0.0 0.0096 15.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_24 PF13578.6 RLN93222.1 - 0.017 16.1 0.5 0.13 13.2 0.0 2.5 2 2 0 2 2 2 0 Methyltransferase domain Methyltransf_15 PF09445.10 RLN93222.1 - 0.042 13.4 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_PK PF05891.12 RLN93222.1 - 0.06 12.9 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_3 PF01596.17 RLN93222.1 - 0.084 12.0 0.0 0.21 10.7 0.0 1.6 1 1 0 1 1 1 0 O-methyltransferase Peptidase_S10 PF00450.22 RLN93223.1 - 1.7e-47 162.8 0.0 2.1e-47 162.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Ysc84 PF04366.12 RLN93224.1 - 5e-43 145.9 0.1 6e-43 145.6 0.1 1.1 1 0 0 1 1 1 1 Las17-binding protein actin regulator Rrp44_CSD1 PF17216.3 RLN93224.1 - 0.22 11.2 0.0 12 5.6 0.0 2.2 2 0 0 2 2 2 0 Rrp44-like cold shock domain Mpv17_PMP22 PF04117.12 RLN93225.1 - 1.2e-23 83.1 1.6 1.8e-23 82.5 1.3 1.5 1 1 0 1 1 1 1 Mpv17 / PMP22 family TMEM171 PF15471.6 RLN93226.1 - 6.2 5.7 7.1 1.8 7.5 0.2 2.4 3 0 0 3 3 3 0 Transmembrane protein family 171 ATG16 PF08614.11 RLN93226.1 - 6.9 6.8 47.2 0.68 10.1 32.0 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 RLN93226.1 - 9 5.5 33.3 5.6 6.2 2.9 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Fer4_5 PF12801.7 RLN93227.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain Piwi PF02171.17 RLN93228.1 - 5.8e-92 308.2 0.0 9.2e-92 307.5 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 RLN93228.1 - 6.5e-18 65.7 0.0 1.2e-17 64.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 RLN93228.1 - 2.8e-16 58.9 0.0 6e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 RLN93228.1 - 3.9e-16 59.1 0.0 7.4e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 RLN93228.1 - 8.8e-10 38.7 0.2 2.4e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 Mid domain of argonaute ArgoL2 PF16488.5 RLN93228.1 - 3.7e-08 33.6 0.0 8e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain Med7 PF05983.11 RLN93229.1 - 5e-27 95.2 12.9 1.8e-23 83.6 12.9 3.1 1 1 0 1 1 1 1 MED7 protein Med4 PF10018.9 RLN93229.1 - 0.057 13.1 0.3 0.092 12.4 0.3 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF3384 PF11864.8 RLN93229.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) Herpes_UL6 PF01763.16 RLN93229.1 - 0.19 10.2 0.1 0.23 10.0 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like HAV_VP PF12944.7 RLN93230.1 - 0.082 12.9 0.0 0.086 12.8 0.0 1.2 1 0 0 1 1 1 0 Hepatitis A virus viral protein VP FliH PF02108.16 RLN93230.1 - 0.099 12.7 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH Arm PF00514.23 RLN93231.1 - 1.3e-30 104.4 2.1 5e-08 32.7 0.0 5.2 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 RLN93231.1 - 7.5e-07 29.1 0.0 0.4 10.7 0.0 3.3 3 0 0 3 3 3 3 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 RLN93231.1 - 4.2e-06 26.6 0.1 9.4 6.8 0.0 4.7 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 RLN93231.1 - 7.2e-06 26.4 6.2 0.064 13.8 0.1 4.2 2 2 2 4 4 4 4 HEAT-like repeat HEAT_2 PF13646.6 RLN93231.1 - 1.9e-05 25.0 6.5 0.0008 19.8 1.1 2.6 1 1 1 2 2 2 2 HEAT repeats HEAT_PBS PF03130.16 RLN93231.1 - 0.4 11.5 16.3 5.6 7.9 0.0 5.7 5 2 0 5 5 5 0 PBS lyase HEAT-like repeat Rotamase_2 PF13145.6 RLN93231.1 - 0.51 11.2 4.1 18 6.2 1.0 2.2 2 0 0 2 2 2 0 PPIC-type PPIASE domain ORC3_N PF07034.11 RLN93232.1 - 0.0083 15.3 0.7 0.013 14.6 0.7 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Oleosin PF01277.17 RLN93232.1 - 0.015 15.0 3.6 0.031 14.0 3.6 1.4 1 0 0 1 1 1 0 Oleosin DUF4396 PF14342.6 RLN93232.1 - 0.05 14.0 0.6 0.086 13.2 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) DUF3827 PF12877.7 RLN93232.1 - 3.6 5.8 4.0 5.1 5.3 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF997 PF06196.12 RLN93232.1 - 5.6 7.1 7.2 4.2 7.4 5.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF997) Ly49 PF08391.10 RLN93233.1 - 0.73 10.2 5.2 0.63 10.4 4.1 1.5 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region FUSC-like PF12805.7 RLN93233.1 - 0.84 8.7 2.9 1.2 8.1 1.9 1.6 1 1 1 2 2 2 0 FUSC-like inner membrane protein yccS Acetyltransf_1 PF00583.25 RLN93234.1 - 1e-14 54.8 0.0 1.3e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RLN93234.1 - 2.7e-13 50.2 0.0 3.8e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RLN93234.1 - 4.6e-12 46.0 0.0 6.8e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 RLN93234.1 - 2.6e-06 27.5 0.1 2.5e-05 24.4 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN93234.1 - 1.4e-05 25.0 0.0 2.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 RLN93234.1 - 0.0039 17.3 0.0 0.0072 16.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 RLN93234.1 - 0.046 13.8 0.0 0.1 12.7 0.0 1.6 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase GNAT_acetyltr_2 PF13718.6 RLN93234.1 - 0.065 12.6 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Acetyltransf_6 PF13480.7 RLN93234.1 - 0.066 13.4 0.0 0.096 12.8 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4684 PF15736.5 RLN93234.1 - 0.17 10.5 0.4 0.25 10.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) MOZ_SAS PF01853.18 RLN93234.1 - 0.18 11.5 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family Ribul_P_3_epim PF00834.19 RLN93235.1 - 2.8e-68 229.2 0.0 3.2e-68 229.0 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PG_binding_3 PF09374.10 RLN93235.1 - 0.076 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Predicted Peptidoglycan domain QRPTase_C PF01729.19 RLN93235.1 - 0.13 12.1 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain JmjN PF02375.17 RLN93235.1 - 0.18 11.8 0.0 0.47 10.5 0.0 1.7 1 0 0 1 1 1 0 jmjN domain TMP-TENI PF02581.17 RLN93235.1 - 0.19 11.0 1.0 2.7 7.3 0.2 2.9 2 1 1 3 3 3 0 Thiamine monophosphate synthase MRP-S33 PF08293.11 RLN93236.1 - 1.2e-08 35.1 0.7 4.5e-08 33.2 0.7 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit S27 JAB PF01398.21 RLN93237.1 - 1.6e-12 47.4 0.0 3.7e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HrpB7 PF09486.10 RLN93238.1 - 0.0028 18.1 2.0 0.0028 18.1 2.0 3.6 3 0 0 3 3 3 1 Bacterial type III secretion protein (HrpB7) Paramyx_P_V_C PF03210.13 RLN93238.1 - 0.092 12.5 0.5 0.59 9.9 0.2 2.2 2 0 0 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal Spc7 PF08317.11 RLN93238.1 - 1.5 7.7 9.1 0.42 9.4 2.1 2.9 2 1 0 2 2 2 0 Spc7 kinetochore protein OmpH PF03938.14 RLN93238.1 - 4 7.8 10.6 3.7 7.9 0.6 2.9 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) COG5 PF10392.9 RLN93238.1 - 4.9 7.3 7.0 6.4 7.0 0.1 3.4 4 0 0 4 4 4 0 Golgi transport complex subunit 5 RL10P_insert PF17777.1 RLN93239.1 - 1.3e-21 76.3 0.0 2.2e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 RLN93239.1 - 1.3e-18 67.0 0.2 1.8e-18 66.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 F-actin_cap_A PF01267.17 RLN93239.1 - 0.037 13.5 0.3 0.053 12.9 0.3 1.2 1 0 0 1 1 1 0 F-actin capping protein alpha subunit HECT PF00632.25 RLN93241.1 - 5.4e-59 200.2 0.0 1e-58 199.3 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MIB_HERC2 PF06701.13 RLN93241.1 - 4e-20 71.8 9.4 3e-16 59.4 4.1 2.7 2 0 0 2 2 2 2 Mib_herc2 Laminin_G_3 PF13385.6 RLN93241.1 - 1.1e-15 58.1 0.0 3.7e-07 30.4 0.0 4.0 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily SPRY PF00622.28 RLN93241.1 - 7.3e-10 39.0 0.0 1.3e-06 28.5 0.0 3.1 2 0 0 2 2 2 2 SPRY domain CUB PF00431.20 RLN93241.1 - 5.2e-06 26.8 1.0 0.35 11.2 0.3 4.1 3 0 0 3 3 3 2 CUB domain Arm PF00514.23 RLN93241.1 - 0.0056 16.7 0.6 0.72 10.0 0.1 2.9 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN93241.1 - 0.0064 16.7 0.1 0.037 14.3 0.1 2.5 1 0 0 1 1 1 1 HEAT repeat Laminin_G_2 PF02210.24 RLN93241.1 - 0.15 12.7 0.0 1.9 9.1 0.0 2.7 3 0 0 3 3 3 0 Laminin G domain YqjK PF13997.6 RLN93242.1 - 0.021 15.0 1.2 0.059 13.6 0.4 2.1 2 0 0 2 2 2 0 YqjK-like protein UPF0242 PF06785.11 RLN93242.1 - 0.16 12.0 1.1 0.25 11.4 1.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Kinesin PF00225.23 RLN93243.1 - 6.4e-109 363.9 0.0 6.4e-109 363.9 0.0 2.3 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RLN93243.1 - 9.1e-24 84.1 0.0 3.5e-23 82.2 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding MIP-T3 PF10243.9 RLN93243.1 - 4.8e-11 42.6 0.3 4e-10 39.7 0.0 2.7 2 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 CH-like domain DUF733 PF05306.11 RLN93244.1 - 0.071 13.4 4.3 0.13 12.6 3.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF733) Pro_isomerase PF00160.21 RLN93245.1 - 1.8e-50 171.3 0.1 2.9e-50 170.6 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FKBP_C PF00254.28 RLN93245.1 - 9.9e-12 45.0 0.2 1.4e-06 28.5 0.0 3.0 2 1 1 3 3 3 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 RLN93245.1 - 3.7e-10 39.1 0.3 0.0011 18.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 RLN93245.1 - 2.1e-05 24.8 0.2 0.035 14.7 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN93245.1 - 4.5e-05 23.1 0.6 0.62 10.0 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN93245.1 - 6e-05 22.9 0.2 0.83 10.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN93245.1 - 0.00011 22.7 1.3 0.0018 18.7 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN93245.1 - 0.0036 17.6 0.5 0.039 14.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN93245.1 - 0.011 15.7 0.1 0.19 11.8 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN93245.1 - 0.014 15.5 0.1 5.4 7.2 0.0 2.5 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 RLN93245.1 - 0.02 14.6 2.4 10 5.9 0.0 4.2 4 0 0 4 4 4 0 TPR repeat TPR_16 PF13432.6 RLN93245.1 - 0.023 15.3 1.1 1.4 9.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3808 PF10300.9 RLN93245.1 - 0.036 12.8 0.1 0.048 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) DUF1811 PF08838.10 RLN93245.1 - 0.079 13.2 1.4 2.4 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) TPR_14 PF13428.6 RLN93245.1 - 0.15 13.0 1.1 2.5 9.1 0.2 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 RLN93245.1 - 0.18 12.0 0.1 0.33 11.1 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat RNA_pol_Rpb1_1 PF04997.12 RLN93246.1 - 4.5e-21 75.5 0.0 5.1e-21 75.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 Ectatomin PF06457.11 RLN93246.1 - 0.13 12.1 0.1 4.7 7.2 0.1 2.2 2 0 0 2 2 2 0 Ectatomin Cytochrome_CBB3 PF13442.6 RLN93246.1 - 0.29 11.5 2.1 14 6.1 0.1 2.4 2 1 1 3 3 3 0 Cytochrome C oxidase, cbb3-type, subunit III Hydrolase_6 PF13344.6 RLN93247.1 - 6.1e-11 42.3 0.0 1.1e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RLN93247.1 - 7.3e-11 42.0 0.0 1.5e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 RLN93247.1 - 9.8e-05 22.5 0.1 0.00038 20.6 0.0 2.0 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RLN93247.1 - 0.00083 19.7 0.0 0.0035 17.7 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Kazal_1 PF00050.21 RLN93248.1 - 7.1e-58 192.4 42.6 9.6e-13 47.9 2.0 5.2 5 0 0 5 5 5 5 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 RLN93248.1 - 1e-47 160.0 53.7 2.6e-10 40.3 5.2 5.2 5 0 0 5 5 5 5 Kazal-type serine protease inhibitor domain TruB-C_2 PF09157.11 RLN93248.1 - 0.25 11.4 0.0 36 4.5 0.0 2.4 2 0 0 2 2 2 0 Pseudouridine synthase II TruB, C-terminal A2L_zn_ribbon PF08792.10 RLN93248.1 - 0.7 9.7 11.6 6.2 6.7 0.5 5.8 6 0 0 6 6 6 0 A2L zinc ribbon domain Lon_C PF05362.13 RLN93249.1 - 2e-53 181.0 1.8 5.2e-51 173.1 1.8 3.3 1 1 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 RLN93249.1 - 1.4e-29 103.4 0.0 3.6e-29 102.1 0.0 1.7 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 RLN93249.1 - 8.2e-21 74.8 0.0 2.8e-20 73.1 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RLN93249.1 - 5.4e-11 42.6 0.0 1.5e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 RLN93249.1 - 1e-05 25.3 0.0 2.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 RLN93249.1 - 7.9e-05 21.7 0.0 0.00013 21.0 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 RLN93249.1 - 0.00053 20.3 1.2 0.079 13.2 0.1 3.4 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 RLN93249.1 - 0.00099 18.9 0.0 0.0035 17.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 RLN93249.1 - 0.0036 17.7 4.7 0.0038 17.6 0.0 3.2 2 2 1 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 RLN93249.1 - 0.0042 17.0 0.0 0.0092 15.9 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_2 PF07724.14 RLN93249.1 - 0.0062 16.7 0.0 0.019 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 RLN93249.1 - 0.01 15.6 0.1 0.058 13.1 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 RLN93249.1 - 0.015 15.8 0.0 0.043 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 RLN93249.1 - 0.024 14.5 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 RLN93249.1 - 0.29 11.3 2.4 0.81 9.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain ADP_ribosyl_GH PF03747.14 RLN93250.1 - 1.6e-48 165.9 6.3 2e-48 165.6 6.3 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase zf-C3HC4_3 PF13920.6 RLN93251.1 - 7.1e-13 48.2 5.6 1.2e-12 47.5 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) K-box PF01486.17 RLN93251.1 - 0.00011 22.3 2.5 0.00011 22.3 2.5 1.9 2 0 0 2 2 2 1 K-box region Prok-RING_4 PF14447.6 RLN93251.1 - 0.0012 18.7 5.9 0.0023 17.8 5.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN93251.1 - 0.023 14.6 4.9 0.044 13.8 4.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF3140 PF11338.8 RLN93251.1 - 0.13 12.7 1.8 6.2 7.3 0.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3140) zf-RING_2 PF13639.6 RLN93251.1 - 0.14 12.5 6.2 0.27 11.6 6.2 1.5 1 0 0 1 1 1 0 Ring finger domain VPS11_C PF12451.8 RLN93251.1 - 5.7 7.2 7.0 5.9 7.2 0.6 3.3 2 1 1 3 3 3 0 Vacuolar protein sorting protein 11 C terminal LRIF1 PF15741.5 RLN93252.1 - 0.043 12.4 11.3 0.045 12.3 11.3 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 MCM_bind PF09739.9 RLN93252.1 - 0.16 10.4 6.8 0.19 10.2 6.8 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF4692 PF15763.5 RLN93252.1 - 0.17 12.4 6.5 0.2 12.1 6.5 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) FAM104 PF15434.6 RLN93252.1 - 0.23 12.1 10.6 0.35 11.5 10.6 1.4 1 0 0 1 1 1 0 Family 104 TFIIF_alpha PF05793.12 RLN93252.1 - 0.29 9.7 21.4 0.36 9.4 21.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sporozoite_P67 PF05642.11 RLN93252.1 - 0.45 8.6 5.9 0.49 8.4 5.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Apc15p PF05841.11 RLN93252.1 - 0.49 11.2 8.9 0.69 10.7 8.9 1.1 1 0 0 1 1 1 0 Apc15p protein RR_TM4-6 PF06459.12 RLN93252.1 - 0.61 9.9 9.1 0.69 9.7 9.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 RLN93252.1 - 1.5 8.8 13.9 1.8 8.5 13.9 1.0 1 0 0 1 1 1 0 Protein Family FAM60A CDC45 PF02724.14 RLN93252.1 - 1.7 6.8 13.7 2 6.6 13.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 RLN93252.1 - 1.7 7.3 10.0 2.1 7.0 10.0 1.0 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 RLN93252.1 - 2.1 7.1 7.9 2.4 6.9 7.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter FmiP_Thoc5 PF09766.9 RLN93252.1 - 2.3 7.4 13.0 0.74 9.0 10.1 1.4 1 1 0 1 1 1 0 Fms-interacting protein/Thoc5 Zip PF02535.22 RLN93252.1 - 5.3 6.2 7.9 6.1 6.0 7.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Paramyxo_ncap PF00973.19 RLN93252.1 - 6.3 5.6 8.3 7 5.4 8.3 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein AP3D1 PF06375.11 RLN93252.1 - 7.9 6.7 26.2 4.5 7.5 24.5 1.6 1 1 0 1 1 1 0 AP-3 complex subunit delta-1 BRF1 PF07741.13 RLN93252.1 - 8.1 6.9 18.2 20 5.6 18.2 1.6 1 1 0 1 1 1 0 Brf1-like TBP-binding domain V-ATPase_C PF03223.15 RLN93253.1 - 2.3e-77 260.9 0.0 2.9e-77 260.6 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DndB PF14072.6 RLN93253.1 - 0.08 12.1 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 DNA-sulfur modification-associated Mst1_SARAH PF11629.8 RLN93253.1 - 0.22 11.6 0.8 0.65 10.1 0.8 1.7 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 Tyrosinase PF00264.20 RLN93255.1 - 2e-23 83.9 2.9 2.1e-23 83.8 0.3 2.2 2 1 0 2 2 2 1 Common central domain of tyrosinase DUF5363 PF17320.2 RLN93255.1 - 0.12 12.3 0.5 0.28 11.1 0.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5363) LRR_adjacent PF08191.11 RLN93255.1 - 0.13 12.5 0.0 0.59 10.4 0.0 2.2 2 0 0 2 2 2 0 LRR adjacent MFS18 PF17352.2 RLN93255.1 - 0.16 12.4 0.5 0.56 10.6 0.5 1.9 1 0 0 1 1 1 0 Male Flower Specific protein 18 DUF775 PF05603.12 RLN93256.1 - 3.1e-11 43.2 0.3 3.1e-11 43.2 0.3 3.3 2 2 1 3 3 3 1 Protein of unknown function (DUF775) bZIP_1 PF00170.21 RLN93256.1 - 1.2e-05 25.3 6.7 2.3e-05 24.4 6.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RLN93256.1 - 0.048 13.8 5.3 0.14 12.3 5.3 1.7 1 0 0 1 1 1 0 Basic region leucine zipper Tyrosinase PF00264.20 RLN93257.1 - 1.5e-24 87.5 0.1 1.5e-24 87.5 0.1 2.4 2 0 0 2 2 2 1 Common central domain of tyrosinase CDC27 PF09507.10 RLN93257.1 - 0.87 8.9 4.2 1.5 8.2 4.2 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 EB PF01683.18 RLN93257.1 - 5.4 7.4 8.6 16 5.9 1.5 3.0 3 0 0 3 3 3 0 EB module Tyrosinase PF00264.20 RLN93258.1 - 1.2e-22 81.3 0.4 1.8e-21 77.5 0.4 2.2 1 1 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.20 RLN93259.1 - 2.8e-23 83.4 0.3 2.8e-23 83.4 0.3 2.3 2 1 0 2 2 2 1 Common central domain of tyrosinase Kelch_5 PF13854.6 RLN93262.1 - 4.2e-24 84.1 0.7 0.00074 19.4 0.0 6.5 5 1 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 RLN93262.1 - 1.3e-18 66.7 0.2 6.2e-07 29.3 0.0 5.2 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 RLN93262.1 - 2.1e-18 65.9 5.4 3.6e-07 30.2 0.1 6.2 4 1 1 5 5 5 3 Kelch motif fn3 PF00041.21 RLN93262.1 - 2.4e-15 56.6 0.7 4.7e-06 26.9 0.0 5.3 4 1 0 4 4 4 2 Fibronectin type III domain Gly_rich PF12810.7 RLN93262.1 - 8.4e-15 55.3 57.2 9.3e-09 35.6 29.1 2.5 2 0 0 2 2 2 2 Glycine rich protein Kelch_1 PF01344.25 RLN93262.1 - 1.3e-13 50.3 0.0 0.0052 16.4 0.1 5.5 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 RLN93262.1 - 2.2e-10 40.5 24.6 0.0057 16.9 0.0 8.1 7 1 0 7 7 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 RLN93262.1 - 1.4e-09 37.5 0.1 0.014 15.4 0.0 4.0 3 0 0 3 3 3 3 Kelch motif Pur_ac_phosph_N PF16656.5 RLN93262.1 - 0.00027 21.4 0.4 0.012 16.1 0.0 3.5 4 0 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 RLN93262.1 - 0.0078 16.1 0.0 0.027 14.3 0.0 2.0 1 0 0 1 1 1 1 Tissue factor P_proprotein PF01483.20 RLN93262.1 - 0.056 13.5 0.0 8.5 6.5 0.0 2.9 2 0 0 2 2 2 0 Proprotein convertase P-domain Aminotran_5 PF00266.19 RLN93263.1 - 6.7e-16 58.2 0.0 1.3e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DDE_1 PF03184.19 RLN93264.1 - 7.6e-15 55.0 0.0 3.6e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN93264.1 - 0.0005 20.0 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Arrestin_C PF02752.22 RLN93266.1 - 2.9e-07 31.0 0.0 6.7e-06 26.6 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 RLN93266.1 - 8e-05 22.7 0.1 1.2 9.2 0.0 3.3 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain MULE PF10551.9 RLN93267.1 - 4.1e-05 23.9 0.9 8.1e-05 23.0 0.4 1.7 2 0 0 2 2 2 1 MULE transposase domain Sugar_tr PF00083.24 RLN93268.1 - 7.2e-38 130.6 32.7 2.5e-36 125.6 32.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN93268.1 - 1.4e-27 96.6 37.9 5.9e-24 84.7 26.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 RLN93268.1 - 0.027 13.4 14.7 0.041 12.7 6.4 3.0 2 1 1 3 3 3 0 MFS_1 like family DUF5353 PF17304.2 RLN93268.1 - 0.63 9.8 0.1 0.63 9.8 0.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5353) Glyco_hydro_3 PF00933.21 RLN93269.1 - 6.9e-52 176.8 0.0 9.1e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN93269.1 - 2e-18 67.1 0.0 3.4e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain IQ PF00612.27 RLN93270.1 - 0.0014 18.2 10.5 0.0024 17.5 4.8 6.4 6 0 0 6 6 6 4 IQ calmodulin-binding motif Dimer_Tnp_hAT PF05699.14 RLN93271.1 - 1.3e-06 28.1 0.0 3.4e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Myb_DNA-binding PF00249.31 RLN93272.1 - 5.2e-12 45.8 0.1 8.1e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain PI-PLC-C1 PF16670.5 RLN93274.1 - 0.012 14.7 0.1 0.031 13.4 0.0 1.6 2 0 0 2 2 2 0 Phosphoinositide phospholipase C, Ca2+-dependent DDT PF02791.17 RLN93274.1 - 0.16 12.3 1.3 4.8 7.6 0.1 2.8 2 0 0 2 2 2 0 DDT domain VPS9 PF02204.18 RLN93275.1 - 1.2e-10 41.5 0.1 2.3e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Phage_holin_3_6 PF07332.11 RLN93275.1 - 0.63 10.1 7.4 1.2 9.2 7.4 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF726 PF05277.12 RLN93275.1 - 4.3 6.2 6.4 6.6 5.6 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) zf-C3HC4_3 PF13920.6 RLN93276.1 - 1.5e-12 47.2 16.2 2.3e-12 46.6 16.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN93276.1 - 5.1e-07 29.4 15.1 5.1e-07 29.4 15.1 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 K-box PF01486.17 RLN93276.1 - 0.0054 16.9 3.2 0.0054 16.9 3.2 3.1 2 1 0 3 3 3 1 K-box region zf-RING_5 PF14634.6 RLN93276.1 - 0.41 10.7 15.1 0.79 9.7 15.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain MscS_porin PF12795.7 RLN93276.1 - 3.8 7.0 9.2 0.26 10.8 2.0 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain MCM PF00493.23 RLN93278.1 - 7.1e-102 339.3 0.0 1.3e-101 338.4 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RLN93278.1 - 1.1e-31 109.3 0.5 3.6e-31 107.6 0.2 1.9 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 RLN93278.1 - 1.9e-19 69.8 0.2 6.8e-19 68.1 0.2 2.0 1 1 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 RLN93278.1 - 3e-14 53.5 0.0 7e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 RLN93278.1 - 2.7e-07 30.2 0.3 0.00016 21.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RLN93278.1 - 1.5e-05 24.8 0.0 4.2e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RLN93278.1 - 2.3e-05 24.4 0.1 0.00014 21.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 RLN93278.1 - 0.014 15.3 0.1 0.049 13.5 0.1 1.9 2 0 0 2 2 2 0 AAA lid domain AAA_16 PF13191.6 RLN93278.1 - 0.022 15.1 0.9 0.084 13.3 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain Mg_chelatase_C PF13335.6 RLN93278.1 - 0.06 14.0 0.3 0.29 11.8 0.3 2.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal AAA PF00004.29 RLN93278.1 - 0.073 13.5 0.3 0.48 10.8 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Acetyltransf_1 PF00583.25 RLN93279.1 - 1.7e-18 66.9 0.0 2.3e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 RLN93279.1 - 1.3e-10 41.0 0.0 2.3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 RLN93279.1 - 3.8e-10 39.8 0.0 3.6e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN93279.1 - 1.1e-09 38.6 0.1 1.6e-09 38.0 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 RLN93279.1 - 4.9e-06 26.3 0.0 6.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 RLN93279.1 - 0.00025 21.8 0.0 0.00029 21.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 RLN93279.1 - 0.014 15.6 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 RLN93279.1 - 0.018 15.1 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 RLN93279.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TPR_11 PF13414.6 RLN93280.1 - 4.1e-06 26.4 0.3 5.1e-06 26.1 0.3 1.1 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 RLN93280.1 - 1.8e-05 24.5 1.0 5.9e-05 22.9 0.3 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN93280.1 - 0.0013 18.5 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN93280.1 - 0.0038 17.8 0.5 0.0067 17.1 0.5 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN93280.1 - 0.025 14.9 0.3 0.14 12.6 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN93280.1 - 0.036 14.6 0.1 0.057 13.9 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN93280.1 - 0.037 14.9 0.1 0.091 13.6 0.1 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 RLN93280.1 - 0.046 14.0 0.1 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PTR2 PF00854.21 RLN93281.1 - 2.7e-59 201.0 7.2 7.1e-59 199.6 7.2 1.7 1 1 0 1 1 1 1 POT family DUF5373 PF17343.2 RLN93281.1 - 0.015 15.2 4.1 0.042 13.7 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5373) Peptidase_S8 PF00082.22 RLN93282.1 - 7.6e-30 104.2 8.2 1.2e-29 103.6 8.2 1.3 1 0 0 1 1 1 1 Subtilase family Peptidase_S8 PF00082.22 RLN93283.1 - 3.7e-28 98.7 9.3 3.7e-28 98.7 9.3 1.5 2 0 0 2 2 2 1 Subtilase family Glyoxalase PF00903.25 RLN93284.1 - 0.001 19.2 0.1 0.0017 18.6 0.1 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Imm27 PF15590.6 RLN93284.1 - 0.067 13.0 0.0 0.095 12.5 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 27 CENP-B_dimeris PF09026.10 RLN93284.1 - 0.077 13.4 0.0 0.098 13.1 0.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pantoate_transf PF02548.15 RLN93285.1 - 5.5e-63 212.8 3.1 4.4e-38 131.2 0.0 3.1 2 1 1 3 3 3 3 Ketopantoate hydroxymethyltransferase DUF4632 PF15451.6 RLN93286.1 - 0.024 14.7 1.5 0.08 13.0 1.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Ribosomal_60s PF00428.19 RLN93286.1 - 7.7 7.2 9.5 1.1 9.9 3.7 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Cnn_1N PF07989.11 RLN93287.1 - 8.4e-05 22.7 1.1 8.4e-05 22.7 1.1 6.2 5 2 1 6 6 6 2 Centrosomin N-terminal motif 1 HALZ PF02183.18 RLN93287.1 - 0.11 12.8 0.2 0.11 12.8 0.2 5.4 7 0 0 7 7 7 0 Homeobox associated leucine zipper UPF0004 PF00919.20 RLN93288.1 - 7.1e-30 102.9 0.1 1.4e-29 102.0 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 RLN93288.1 - 5.5e-29 101.7 0.0 1.2e-28 100.6 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily SNF2_N PF00176.23 RLN93289.1 - 3.3e-71 239.8 0.0 5.6e-71 239.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN93289.1 - 1.5e-18 67.1 0.0 3.8e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 RLN93289.1 - 2.2e-10 40.2 5.0 2.2e-10 40.2 5.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN93289.1 - 5.9e-09 35.7 4.9 1.7e-08 34.2 4.9 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 RLN93289.1 - 4.4e-08 33.3 9.6 8.6e-08 32.4 7.0 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 RLN93289.1 - 4.4e-08 33.0 3.9 1.3e-07 31.5 3.9 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RLN93289.1 - 5.1e-08 32.7 5.8 5.1e-08 32.7 5.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN93289.1 - 3.9e-07 29.8 7.9 3.9e-07 29.8 7.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN93289.1 - 0.00021 21.3 8.1 0.00021 21.3 8.1 2.1 2 0 0 2 2 1 1 RING-type zinc-finger ERCC3_RAD25_C PF16203.5 RLN93289.1 - 0.00085 18.6 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-C3HC4_4 PF15227.6 RLN93289.1 - 0.024 14.8 9.0 0.084 13.0 9.0 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 RLN93289.1 - 0.032 14.1 2.1 0.11 12.4 2.1 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 RLN93289.1 - 0.17 11.5 2.3 0.64 9.7 2.3 2.0 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1644 PF07800.12 RLN93289.1 - 2.2 8.3 5.0 1.7 8.7 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-RING_11 PF17123.5 RLN93289.1 - 5.9 6.7 8.8 8.2 6.3 3.9 2.9 2 0 0 2 2 2 0 RING-like zinc finger STI1 PF17830.1 RLN93290.1 - 3.4e-19 68.5 14.1 2.6e-11 43.3 2.1 3.4 3 0 0 3 3 3 3 STI1 domain FlgN PF05130.12 RLN93290.1 - 0.022 15.2 3.7 0.022 15.2 3.7 3.2 3 1 1 4 4 4 0 FlgN protein Nif11 PF07862.11 RLN93290.1 - 0.91 9.9 12.9 6.2 7.2 1.6 4.3 3 1 0 3 3 3 0 Nif11 domain eIF3_N PF09440.10 RLN93290.1 - 4.1 7.8 15.2 0.2 12.1 0.5 3.4 4 0 0 4 4 4 0 eIF3 subunit 6 N terminal domain Prefoldin_2 PF01920.20 RLN93291.1 - 2.7e-11 43.4 4.9 6.9e-11 42.0 2.4 2.5 1 1 0 2 2 2 1 Prefoldin subunit Methyltr_RsmF_N PF17125.5 RLN93292.1 - 0.031 14.8 0.2 7.2 7.2 0.0 2.3 2 0 0 2 2 2 0 N-terminal domain of 16S rRNA methyltransferase RsmF P_C10 PF14974.6 RLN93293.1 - 2.4e-09 37.2 0.0 5.4e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Protein C10 WD40 PF00400.32 RLN93293.1 - 1.9e-06 28.5 2.4 0.0002 22.1 0.1 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat Ig_3 PF13927.6 RLN93293.1 - 9.1e-06 26.2 0.0 2.7e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 RLN93293.1 - 1e-05 25.5 0.0 3.5e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 RLN93293.1 - 0.00015 21.8 0.0 0.0011 19.1 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain ANAPC4_WD40 PF12894.7 RLN93293.1 - 0.0029 17.9 0.0 4.9 7.5 0.0 3.8 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_7 PF02591.15 RLN93293.1 - 0.19 12.0 3.8 0.4 10.9 1.1 2.6 2 0 0 2 2 2 0 C4-type zinc ribbon domain ESM4 PF15952.5 RLN93293.1 - 0.22 11.9 1.4 6.7 7.1 0.2 2.4 2 0 0 2 2 2 0 Enhancer of split M4 family LSM PF01423.22 RLN93295.1 - 2.4e-15 56.0 0.3 3.1e-15 55.6 0.3 1.2 1 0 0 1 1 1 1 LSM domain N2227 PF07942.12 RLN93296.1 - 4.1e-58 196.7 0.0 2.9e-53 180.8 0.0 2.2 1 1 1 2 2 2 2 N2227-like protein NNMT_PNMT_TEMT PF01234.17 RLN93296.1 - 0.0011 18.2 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.6 RLN93296.1 - 0.018 14.9 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 RLN93296.1 - 0.023 15.5 0.0 0.046 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 RLN93296.1 - 0.036 12.6 0.1 0.055 12.0 0.1 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.12 RLN93296.1 - 0.078 13.6 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TPR_12 PF13424.6 RLN93297.1 - 0.036 14.4 2.1 0.49 10.7 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 RLN93297.1 - 0.31 11.2 2.5 1.5 9.0 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L37 PF08561.10 RLN93298.1 - 2.1e-07 31.5 4.3 2.4e-07 31.3 0.0 2.2 2 1 1 3 3 3 1 Mitochondrial ribosomal protein L37 EF_assoc_1 PF08355.12 RLN93298.1 - 0.067 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 EF hand associated GFO_IDH_MocA_C PF02894.17 RLN93299.1 - 8.7e-08 32.2 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Phage_T4_Gp30_7 PF06919.11 RLN93299.1 - 0.068 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Phage Gp30.7 protein JAB PF01398.21 RLN93301.1 - 3.7e-31 107.6 0.0 1.2e-30 105.9 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 RLN93301.1 - 2.5e-10 40.7 0.2 4.7e-10 39.9 0.2 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 RLN93301.1 - 0.00061 19.5 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain G10 PF01125.17 RLN93301.1 - 0.022 14.6 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 G10 protein Env-gp36 PF09590.10 RLN93302.1 - 0.0038 15.7 0.0 0.0049 15.4 0.0 1.1 1 0 0 1 1 1 1 Lentivirus surface glycoprotein Fringe PF02434.16 RLN93302.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Fringe-like Xpo1 PF08389.12 RLN93304.1 - 2e-22 79.8 0.2 1e-20 74.3 0.0 3.1 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 RLN93304.1 - 6.1e-06 26.1 0.0 2.4e-05 24.1 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain MNR PF15718.5 RLN93304.1 - 0.032 12.4 0.1 0.051 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein moonraker ERAP1_C PF11838.8 RLN93305.1 - 4.4e-71 240.0 0.4 7.1e-71 239.3 0.4 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 RLN93305.1 - 2.5e-41 141.7 2.2 4.1e-41 140.9 2.2 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain PHP PF02811.19 RLN93306.1 - 0.12 12.6 0.0 0.14 12.5 0.0 1.1 1 0 0 1 1 1 0 PHP domain cNMP_binding PF00027.29 RLN93307.1 - 1e-18 67.1 0.0 4.1e-12 46.0 0.0 3.9 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN93307.1 - 1.1e-11 44.5 20.0 3.7e-07 29.6 1.9 3.4 3 0 0 3 3 3 3 Ion transport protein Ion_trans_2 PF07885.16 RLN93307.1 - 4.8e-09 36.1 11.5 7e-05 22.7 2.1 3.4 3 0 0 3 3 3 2 Ion channel RabGAP-TBC PF00566.18 RLN93308.1 - 7.6e-08 32.3 1.0 7.6e-08 32.3 1.0 2.4 3 1 0 3 3 3 1 Rab-GTPase-TBC domain Tub PF01167.18 RLN93308.1 - 2 8.1 8.3 3.6 7.3 8.3 1.4 1 0 0 1 1 1 0 Tub family Kinesin PF00225.23 RLN93309.1 - 2.2e-58 197.8 0.0 3.1e-58 197.3 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN93309.1 - 4.1e-06 26.8 0.0 8.8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 RLN93309.1 - 0.00015 22.1 0.6 0.0088 16.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 RLN93309.1 - 0.0031 17.1 0.1 0.0075 15.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 RLN93309.1 - 0.0047 17.3 0.1 0.023 15.1 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 RLN93309.1 - 0.0084 16.5 0.0 0.026 14.9 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 RLN93309.1 - 0.032 14.3 0.0 0.058 13.5 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MADF_DNA_bdg PF10545.9 RLN93309.1 - 0.038 14.3 1.8 1.5 9.2 0.8 2.8 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like AAA_30 PF13604.6 RLN93309.1 - 0.044 13.5 1.0 0.086 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RLN93309.1 - 0.088 12.5 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 RLN93309.1 - 0.092 12.7 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SRP54 PF00448.22 RLN93309.1 - 0.13 11.8 0.1 0.6 9.7 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DDE_1 PF03184.19 RLN93310.1 - 4.2e-33 114.5 0.1 6.4e-33 113.9 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN93310.1 - 3.2e-09 36.7 0.1 1.5e-08 34.5 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 RLN93310.1 - 5.8e-05 22.7 0.8 0.00027 20.6 0.1 2.3 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain DDE_3 PF13358.6 RLN93310.1 - 0.021 14.6 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease FAM199X PF15814.5 RLN93310.1 - 1.1 8.3 2.7 1.7 7.6 2.7 1.3 1 0 0 1 1 1 0 Protein family FAM199X Cpn60_TCP1 PF00118.24 RLN93311.1 - 5.8e-23 81.3 0.0 1e-22 80.4 0.0 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-RING_11 PF17123.5 RLN93313.1 - 9.4e-12 44.5 1.4 3.7e-11 42.6 1.4 2.1 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 RLN93313.1 - 1.5e-11 44.4 3.9 1.5e-11 44.4 3.9 3.6 4 0 0 4 4 3 1 Ring finger domain zf-RING_UBOX PF13445.6 RLN93313.1 - 3.5e-08 33.3 0.3 3.5e-08 33.3 0.3 3.6 3 1 1 4 4 4 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN93313.1 - 7.6e-08 32.2 2.7 7.6e-08 32.2 2.7 4.0 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RLN93313.1 - 8.7e-08 31.9 3.3 8.7e-08 31.9 3.3 4.0 5 0 0 5 5 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN93313.1 - 2.2e-06 27.4 3.8 2.2e-06 27.4 3.8 4.1 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 RLN93313.1 - 3.2e-05 23.6 8.4 0.0002 21.1 3.5 3.4 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 RLN93313.1 - 0.0001 22.0 1.9 0.0001 22.0 1.9 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RLN93313.1 - 0.0003 20.9 10.1 0.0068 16.5 2.4 4.2 4 1 0 4 4 4 1 zinc finger of C3HC4-type, RING PHD PF00628.29 RLN93313.1 - 0.006 16.4 4.5 0.006 16.4 4.5 3.3 4 0 0 4 4 4 1 PHD-finger zf-rbx1 PF12678.7 RLN93313.1 - 0.0062 16.8 6.3 0.0062 16.8 6.3 3.0 2 1 1 3 3 3 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 RLN93313.1 - 0.011 15.8 2.0 0.011 15.8 2.0 2.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 RLN93313.1 - 0.016 15.1 0.7 0.016 15.1 0.7 3.8 4 1 0 4 4 4 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 RLN93313.1 - 0.02 14.5 3.8 0.02 14.5 3.8 2.7 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type Ribosomal_L32p PF01783.23 RLN93313.1 - 0.073 13.3 6.0 12 6.3 3.1 3.6 2 1 0 2 2 2 0 Ribosomal L32p protein family zf-TFIIB PF13453.6 RLN93313.1 - 0.078 12.3 7.5 1 8.7 0.9 3.7 3 0 0 3 3 3 0 Transcription factor zinc-finger zf-C4_Topoisom PF01396.19 RLN93313.1 - 0.12 12.2 0.9 12 5.8 0.2 2.8 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Zn-ribbon_8 PF09723.10 RLN93313.1 - 0.22 11.7 10.8 0.35 11.0 0.6 3.9 4 0 0 4 4 4 0 Zinc ribbon domain DZR PF12773.7 RLN93313.1 - 0.38 10.8 19.5 0.14 12.2 4.3 3.9 2 1 1 3 3 3 0 Double zinc ribbon Zf_RING PF16744.5 RLN93313.1 - 1 9.5 9.6 0.84 9.8 4.7 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger TRAF6_Z2 PF18048.1 RLN93313.1 - 2.6 8.2 7.1 0.9 9.7 3.2 2.1 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zinc_ribbon_4 PF13717.6 RLN93313.1 - 4.7 7.2 8.3 3.3 7.7 0.2 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 RLN93313.1 - 5.9 7.7 13.7 1.9e+02 2.9 9.9 4.1 3 1 1 4 4 4 0 zinc-ribbon family FtsJ PF01728.19 RLN93314.1 - 7.8e-66 221.5 0.3 9e-66 221.3 0.3 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase ABC_membrane PF00664.23 RLN93315.1 - 5.5e-50 170.5 5.3 8e-50 170.0 5.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN93315.1 - 4.8e-35 121.1 0.1 1.1e-34 119.9 0.1 1.6 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 RLN93315.1 - 2.4e-07 30.4 0.1 4.7e-06 26.2 0.3 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RLN93315.1 - 0.008 16.6 0.7 0.038 14.4 0.4 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 RLN93315.1 - 0.012 15.3 0.1 0.038 13.7 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN93315.1 - 0.017 14.7 0.1 0.13 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 RLN93315.1 - 0.019 14.2 0.1 0.045 13.0 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 RLN93315.1 - 0.02 14.6 0.3 0.039 13.7 0.3 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA PF00004.29 RLN93315.1 - 0.021 15.3 4.6 0.16 12.4 1.8 3.0 3 1 0 3 3 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 RLN93315.1 - 0.025 13.4 0.2 0.067 12.0 0.0 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class SRP54 PF00448.22 RLN93315.1 - 0.026 14.1 0.3 0.13 11.9 0.2 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 RLN93315.1 - 0.039 13.3 0.0 0.088 12.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CbiA PF01656.23 RLN93315.1 - 0.049 13.7 0.3 0.18 11.9 0.3 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 RLN93315.1 - 0.057 13.1 0.2 0.11 12.3 0.2 1.5 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 RLN93315.1 - 0.061 13.1 0.5 0.22 11.3 0.5 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase APS_kinase PF01583.20 RLN93315.1 - 0.063 13.2 0.4 0.26 11.2 0.1 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF2075 PF09848.9 RLN93315.1 - 0.088 12.0 0.7 0.24 10.6 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 RLN93315.1 - 0.091 12.5 1.9 0.28 10.9 1.9 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RLN93315.1 - 0.093 13.0 0.6 2.6 8.3 0.2 2.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 RLN93315.1 - 0.094 12.6 0.0 0.38 10.6 0.0 2.0 2 0 0 2 2 1 0 RsgA GTPase NB-ARC PF00931.22 RLN93315.1 - 0.11 11.6 0.2 0.27 10.4 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.17 RLN93315.1 - 1.6 8.7 3.9 1.6 8.8 1.4 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain Peptidase_M14 PF00246.24 RLN93316.1 - 2.7e-24 86.5 0.0 6.9e-24 85.1 0.0 1.8 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 RLN93316.1 - 0.0064 15.6 0.2 0.014 14.5 0.2 1.5 1 1 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Kinesin PF00225.23 RLN93317.1 - 2.8e-96 322.4 0.1 5.5e-96 321.4 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN93317.1 - 3.5e-21 75.7 0.0 1.7e-20 73.5 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding DUF4407 PF14362.6 RLN93317.1 - 0.06 12.7 23.7 0.65 9.3 17.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) CheZ PF04344.13 RLN93317.1 - 0.082 12.8 14.2 0.2 11.6 14.2 1.6 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ zf-C4pol PF14260.6 RLN93317.1 - 0.13 12.7 3.2 0.71 10.4 0.6 3.1 2 1 1 3 3 3 0 C4-type zinc-finger of DNA polymerase delta TMCO5 PF14992.6 RLN93317.1 - 0.39 10.3 20.4 2 7.9 19.5 2.2 1 1 1 2 2 2 0 TMCO5 family Fib_alpha PF08702.10 RLN93317.1 - 0.8 9.9 18.1 0.42 10.8 11.8 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Allexi_40kDa PF05549.11 RLN93317.1 - 1.8 8.0 14.9 1.9 7.9 3.6 3.0 2 1 1 3 3 3 0 Allexivirus 40kDa protein V_ATPase_I PF01496.19 RLN93317.1 - 2.1 6.2 12.4 3.4 5.5 12.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 RLN93317.1 - 5.8 7.0 13.4 8.7 6.4 8.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 RLN93317.1 - 6.5 6.2 18.1 0.33 10.5 11.3 2.0 2 1 0 2 2 2 0 Exonuclease VII, large subunit PPR_2 PF13041.6 RLN93318.1 - 3.5e-41 139.2 1.3 4.4e-13 49.2 0.1 6.7 3 1 4 7 7 7 6 PPR repeat family PPR PF01535.20 RLN93318.1 - 6.5e-30 101.3 1.8 7.4e-06 25.9 0.1 7.7 7 0 0 7 7 7 5 PPR repeat PPR_3 PF13812.6 RLN93318.1 - 4.1e-28 97.3 0.0 5.3e-11 42.4 0.0 4.4 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 RLN93318.1 - 2.4e-23 81.5 0.1 1.3e-07 31.2 0.0 6.0 7 0 0 7 7 7 3 PPR repeat PPR_long PF17177.4 RLN93318.1 - 1.7e-19 70.0 0.6 4.7e-13 49.0 0.3 3.3 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 RLN93318.1 - 0.00019 20.4 0.0 0.0003 19.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 Clathrin PF00637.20 RLN93318.1 - 0.00035 20.5 0.1 0.0031 17.4 0.1 2.5 1 1 1 2 2 2 1 Region in Clathrin and VPS MNE1 PF13762.6 RLN93318.1 - 0.0017 18.4 0.1 2.7 7.9 0.0 2.9 2 1 0 2 2 2 2 Mitochondrial splicing apparatus component TPR_4 PF07721.14 RLN93318.1 - 0.012 16.2 3.4 4.1 8.3 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN93318.1 - 0.022 15.3 2.8 0.093 13.2 0.6 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat NatB_MDM20 PF09797.9 RLN93318.1 - 0.078 11.9 0.2 0.2 10.5 0.0 1.7 2 0 0 2 2 2 0 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.6 RLN93318.1 - 1.3 10.0 7.9 73 4.6 0.0 5.3 5 1 1 6 6 5 0 Tetratricopeptide repeat PX PF00787.24 RLN93319.1 - 5e-19 68.4 0.4 1.3e-18 67.0 0.4 1.6 1 0 0 1 1 1 1 PX domain DUF4357 PF14267.6 RLN93319.1 - 8.1 6.5 7.9 0.85 9.6 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) Flavokinase PF01687.17 RLN93320.1 - 7.8e-31 106.7 0.0 1.1e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Riboflavin kinase EamA PF00892.20 RLN93321.1 - 3.3e-25 88.8 26.0 7e-14 52.2 12.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 RLN93321.1 - 3e-06 26.8 17.0 0.00011 21.7 1.0 3.0 3 0 0 3 3 3 3 Triose-phosphate Transporter family SLC35F PF06027.12 RLN93321.1 - 1.4e-05 24.8 13.2 0.00021 20.9 1.9 2.1 1 1 1 2 2 2 2 Solute carrier family 35 UAA PF08449.11 RLN93321.1 - 0.0016 17.7 5.4 0.0016 17.7 5.4 1.9 1 1 1 2 2 2 1 UAA transporter family TMEM234 PF10639.9 RLN93321.1 - 0.49 10.4 13.9 0.65 10.0 3.6 3.0 2 1 0 2 2 2 0 Putative transmembrane family 234 Lipase_GDSL_2 PF13472.6 RLN93323.1 - 1.8e-23 83.9 0.1 3.7e-23 82.9 0.1 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RLN93323.1 - 9.2e-14 51.9 0.0 2.5e-13 50.4 0.0 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase WD40_3 PF15911.5 RLN93324.1 - 0.039 14.0 0.1 0.097 12.7 0.0 1.7 2 0 0 2 2 2 0 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 RLN93324.1 - 0.19 10.9 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus BT1 PF03092.16 RLN93325.1 - 1.8e-86 290.5 19.8 5.4e-50 170.1 6.9 3.1 1 1 1 2 2 2 2 BT1 family Sporozoite_P67 PF05642.11 RLN93325.1 - 0.47 8.5 4.2 1.3 7.0 0.3 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen PP2C PF00481.21 RLN93326.1 - 1.8e-45 155.6 0.1 2.5e-45 155.1 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RLN93326.1 - 0.0011 18.6 0.0 0.0029 17.3 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C zf-C3HC4_3 PF13920.6 RLN93327.1 - 3.2e-08 33.3 7.3 3.2e-08 33.3 7.3 4.0 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) R3H PF01424.22 RLN93327.1 - 1.2e-05 25.2 0.3 2.7e-05 24.1 0.3 1.7 1 0 0 1 1 1 1 R3H domain Prok-RING_4 PF14447.6 RLN93327.1 - 0.015 15.1 6.8 0.015 15.1 6.8 2.8 4 0 0 4 4 4 0 Prokaryotic RING finger family 4 zf-C2HE PF16278.5 RLN93327.1 - 0.64 10.5 4.5 6.1 7.4 0.3 2.8 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C3HC4 PF00097.25 RLN93327.1 - 2.3 8.1 24.3 0.042 13.7 8.7 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) ABC2_membrane PF01061.24 RLN93330.1 - 3.2e-35 121.5 24.8 3.6e-35 121.3 24.8 1.0 1 0 0 1 1 1 1 ABC-2 type transporter Sugar_tr PF00083.24 RLN93331.1 - 2.5e-32 112.3 23.1 3.2e-30 105.4 23.1 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN93331.1 - 1.1e-31 110.0 33.0 4.3e-28 98.2 26.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 RLN93331.1 - 0.00066 18.0 8.7 0.0098 14.2 1.5 2.5 2 0 0 2 2 2 2 BT1 family Transgly_assoc PF04226.13 RLN93331.1 - 0.024 14.9 2.4 0.024 14.9 2.4 3.9 5 0 0 5 5 5 0 Transglycosylase associated protein DUF1435 PF07256.12 RLN93331.1 - 0.18 11.9 7.6 0.11 12.6 3.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) Troponin-I_N PF11636.8 RLN93332.1 - 0.025 14.5 1.0 0.06 13.3 1.0 1.6 1 0 0 1 1 1 0 Troponin I residues 1-32 V-SNARE_C PF12352.8 RLN93333.1 - 2.4e-15 56.6 4.6 2.4e-15 56.6 4.6 1.5 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 RLN93333.1 - 0.00016 21.5 0.4 0.00029 20.7 0.4 1.3 1 0 0 1 1 1 1 Sec20 HTH_IclR PF09339.10 RLN93333.1 - 0.1 12.4 0.9 0.19 11.5 0.9 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain Orf78 PF06024.12 RLN93333.1 - 0.13 12.5 0.3 0.28 11.5 0.3 1.5 1 0 0 1 1 1 0 Orf78 (ac78) ABC_tran PF00005.27 RLN93334.1 - 3.7e-15 56.7 0.0 6.6e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 RLN93334.1 - 0.00017 22.0 0.2 0.0016 18.9 0.1 2.4 2 1 1 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 RLN93334.1 - 0.0056 16.6 0.1 0.0086 16.0 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 RLN93334.1 - 0.0089 15.3 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 RLN93334.1 - 0.0099 15.6 0.2 0.019 14.7 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN93334.1 - 0.025 14.9 0.1 0.069 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 RLN93334.1 - 0.037 14.0 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 RLN93334.1 - 0.056 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_25 PF13481.6 RLN93334.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 RLN93334.1 - 0.072 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 RLN93334.1 - 0.078 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Roc PF08477.13 RLN93334.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase VirE PF05272.11 RLN93334.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E RAI16-like PF10257.9 RLN93335.1 - 2.2e-40 138.6 0.1 3.5e-40 138.0 0.1 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein MCD_N PF17408.2 RLN93335.1 - 0.0094 16.1 0.1 0.026 14.6 0.1 1.8 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase N-terminal domain Sporozoite_P67 PF05642.11 RLN93335.1 - 2.4 6.1 4.9 4.1 5.4 4.9 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen C2 PF00168.30 RLN93336.1 - 0.00011 22.4 0.0 0.00024 21.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain IQ PF00612.27 RLN93336.1 - 0.00017 21.1 6.0 0.03 14.1 1.0 4.4 3 0 0 3 3 3 2 IQ calmodulin-binding motif Fibrillarin PF01269.17 RLN93338.1 - 7e-26 90.7 0.0 8.6e-26 90.4 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin zf-TAZ PF02135.16 RLN93340.1 - 4.5e-24 84.7 36.5 5.6e-15 55.6 15.3 5.6 5 1 0 5 5 5 2 TAZ zinc finger HAT_KAT11 PF08214.11 RLN93340.1 - 5.7e-23 81.8 12.1 3.8e-22 79.1 3.9 3.5 2 1 0 2 2 2 1 Histone acetylation protein Bromodomain PF00439.25 RLN93340.1 - 1.4e-18 66.7 2.2 2.6e-18 65.9 0.0 2.6 3 0 0 3 3 3 1 Bromodomain ZZ PF00569.17 RLN93340.1 - 4.9e-10 39.1 8.3 4.9e-10 39.1 8.3 4.0 4 0 0 4 4 4 1 Zinc finger, ZZ type KIX_2 PF16987.5 RLN93340.1 - 1.4e-06 28.2 0.3 1.4e-06 28.2 0.3 2.9 2 0 0 2 2 2 1 KIX domain PHD PF00628.29 RLN93340.1 - 0.0002 21.2 0.7 0.0002 21.2 0.7 5.3 4 1 0 4 4 4 1 PHD-finger DUF902 PF06001.13 RLN93340.1 - 0.0057 17.1 6.3 0.015 15.8 6.3 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF902) KIX PF02172.16 RLN93340.1 - 0.014 15.6 0.0 0.11 12.8 0.0 2.6 1 0 0 1 1 1 0 KIX domain Spectrin PF00435.21 RLN93341.1 - 0.069 13.6 0.6 0.21 12.1 0.6 1.9 1 0 0 1 1 1 0 Spectrin repeat Filamin PF00630.19 RLN93342.1 - 1.8e-66 221.4 0.0 3.7e-14 53.4 0.0 9.8 9 2 0 9 9 9 7 Filamin/ABP280 repeat PA14 PF07691.12 RLN93342.1 - 2.5e-31 108.5 0.0 1.4e-13 50.9 0.0 3.8 3 0 0 3 3 3 3 PA14 domain Invasin_D3 PF09134.10 RLN93342.1 - 3.3e-11 43.3 26.4 0.015 15.6 1.0 8.5 9 0 0 9 9 9 5 Invasin, domain 3 Cadherin_5 PF17892.1 RLN93342.1 - 4.8e-07 29.7 1.8 0.071 13.1 0.4 4.2 4 0 0 4 4 4 2 Cadherin-like domain Calx-beta PF03160.14 RLN93342.1 - 8.5e-07 29.1 0.0 2.7e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 Calx-beta domain Y_Y_Y PF07495.13 RLN93342.1 - 0.0008 19.3 0.2 5.7 7.0 0.1 4.9 5 0 0 5 5 5 1 Y_Y_Y domain DUF4249 PF14054.6 RLN93342.1 - 0.065 12.9 1.0 0.24 11.0 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4249) GLEYA PF10528.9 RLN93342.1 - 0.068 13.6 0.0 31 5.1 0.0 3.4 2 0 0 2 2 2 0 GLEYA domain YtkA PF13115.6 RLN93342.1 - 0.14 12.7 0.0 26 5.5 0.0 3.6 3 0 0 3 3 3 0 YtkA-like RRM_1 PF00076.22 RLN93343.1 - 3.3e-19 68.5 0.0 4.8e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RLN93343.1 - 0.00056 19.5 0.0 0.00072 19.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 RLN93343.1 - 0.014 15.6 0.0 0.022 15.0 0.0 1.2 1 0 0 1 1 1 0 RRM-like domain PHM7_cyt PF14703.6 RLN93343.1 - 0.04 14.2 0.0 0.054 13.7 0.0 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF1045 PF06299.12 RLN93345.1 - 0.0074 16.3 0.1 0.019 14.9 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1045) DEAD PF00270.29 RLN93346.1 - 3.8e-06 26.8 0.4 0.014 15.2 0.1 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN93346.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.8 1 1 0 1 1 1 0 Helicase conserved C-terminal domain CBS PF00571.28 RLN93346.1 - 0.057 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 CBS domain Ank_2 PF12796.7 RLN93347.1 - 5.7e-43 145.4 17.3 1.2e-07 32.1 0.2 12.3 7 4 2 10 10 10 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN93347.1 - 5.5e-40 135.2 15.2 0.0001 22.8 0.1 15.2 11 5 5 16 16 16 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN93347.1 - 5.7e-34 115.7 19.1 7.3e-07 29.3 0.1 11.9 13 1 0 13 13 13 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN93347.1 - 1.8e-22 77.0 19.8 0.037 14.6 0.0 16.1 19 0 0 19 19 19 5 Ankyrin repeat Ank PF00023.30 RLN93347.1 - 2.7e-19 68.7 29.0 0.0028 18.0 0.2 15.9 19 0 0 19 19 19 5 Ankyrin repeat MULE PF10551.9 RLN93350.1 - 0.00013 22.3 0.3 0.006 17.0 0.3 2.7 1 1 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 RLN93350.1 - 0.019 13.9 2.0 0.039 12.8 0.1 2.0 2 0 0 2 2 2 0 Transposase, Mutator family B56 PF01603.20 RLN93351.1 - 1.2e-158 528.5 2.0 1.5e-80 271.2 1.7 2.0 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) ATP-synt_ab PF00006.25 RLN93352.1 - 2e-59 200.8 0.0 2.3e-59 200.6 0.0 1.0 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain RsgA_GTPase PF03193.16 RLN93352.1 - 0.02 14.8 0.1 0.03 14.2 0.1 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 RLN93352.1 - 0.023 15.0 0.3 0.045 14.1 0.3 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RLN93352.1 - 0.14 12.7 0.3 0.23 12.0 0.3 1.3 1 0 0 1 1 1 0 ABC transporter TrwB_AAD_bind PF10412.9 RLN93352.1 - 0.14 11.0 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 RLN93352.1 - 0.17 11.4 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 RLN93352.1 - 0.29 10.3 0.2 0.45 9.7 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) VPS9 PF02204.18 RLN93354.1 - 2.3e-14 53.5 0.0 1e-13 51.4 0.0 2.1 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Cwf_Cwc_15 PF04889.12 RLN93354.1 - 0.0028 17.4 7.4 0.0047 16.7 7.4 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF2293 PF10056.9 RLN93354.1 - 0.096 12.9 0.1 0.29 11.4 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) DSPc PF00782.20 RLN93356.1 - 6.9e-34 116.5 0.0 1.1e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RLN93356.1 - 0.011 15.3 0.0 0.03 13.9 0.0 1.6 1 1 1 2 2 2 0 Protein-tyrosine phosphatase DUF5524 PF17662.1 RLN93356.1 - 0.035 13.5 0.5 0.064 12.6 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5524) Gelsolin PF00626.22 RLN93356.1 - 0.049 13.5 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Gelsolin repeat DUF1962 PF09227.10 RLN93356.1 - 0.13 12.7 0.1 0.37 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1962) Myosin_head PF00063.21 RLN93358.1 - 2.6e-200 667.1 0.0 3.7e-200 666.6 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) ThiF PF00899.21 RLN93358.1 - 8e-88 293.9 0.0 2.6e-61 207.1 0.0 3.0 3 1 0 3 3 3 2 ThiF family UBA_e1_thiolCys PF10585.9 RLN93358.1 - 8.9e-72 242.0 1.7 2.2e-71 240.7 1.7 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Ank_2 PF12796.7 RLN93358.1 - 1.9e-24 86.0 3.6 1.5e-10 41.5 0.2 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 RLN93358.1 - 3.1e-18 65.3 1.0 0.0016 18.8 0.1 6.4 5 0 0 5 5 5 5 Ankyrin repeat E1_4HB PF16191.5 RLN93358.1 - 2.4e-16 59.7 0.0 9.1e-16 57.8 0.0 2.1 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Ank_4 PF13637.6 RLN93358.1 - 3.6e-16 59.3 1.3 2.6e-05 24.7 0.0 5.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN93358.1 - 7.6e-15 53.6 1.9 0.003 17.9 0.0 6.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 RLN93358.1 - 8.3e-13 48.3 2.6 0.00016 21.9 0.0 4.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) E1_FCCH PF16190.5 RLN93358.1 - 1.1e-07 31.9 1.3 2e-06 27.9 0.4 3.4 2 1 0 2 2 2 1 Ubiquitin-activating enzyme E1 FCCH domain FYVE PF01363.21 RLN93358.1 - 2.9e-06 27.3 1.9 7.1e-06 26.1 1.9 1.6 1 0 0 1 1 1 1 FYVE zinc finger E1_UFD PF09358.10 RLN93358.1 - 0.0093 16.7 0.0 0.22 12.2 0.0 2.6 1 1 0 1 1 1 1 Ubiquitin fold domain Tap-RNA_bind PF09162.10 RLN93358.1 - 0.019 14.8 0.2 0.069 13.0 0.0 2.0 2 0 0 2 2 2 0 Tap, RNA-binding IQ PF00612.27 RLN93358.1 - 0.029 14.2 4.5 0.82 9.6 0.4 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_19 PF13245.6 RLN93358.1 - 0.033 14.5 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RLN93358.1 - 0.079 13.2 0.0 0.35 11.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 RLN93358.1 - 0.11 12.3 0.5 0.78 9.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 RLN93358.1 - 0.46 10.9 2.8 1.1 9.6 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain PhoLip_ATPase_C PF16212.5 RLN93359.1 - 4e-73 246.2 23.5 4e-73 246.2 23.5 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RLN93359.1 - 1e-18 66.7 0.7 1e-18 66.7 0.7 1.8 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RLN93359.1 - 2.6e-11 44.2 0.0 1.2e-05 25.8 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN93359.1 - 4.1e-09 36.4 0.0 2.6e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RLN93359.1 - 1.8e-05 24.4 0.0 5e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RLN93359.1 - 0.0029 17.4 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase GFO_IDH_MocA PF01408.22 RLN93362.1 - 1.7e-07 32.1 0.0 3.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 RLN93362.1 - 2.2e-05 24.4 0.0 4.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Gp_dh_N PF00044.24 RLN93362.1 - 0.0086 16.4 0.0 0.03 14.6 0.0 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 RLN93362.1 - 0.028 14.6 0.0 0.093 12.9 0.0 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Pkinase_Tyr PF07714.17 RLN93363.1 - 4.3e-42 144.2 0.0 6.5e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN93363.1 - 7.7e-34 117.3 0.0 1.2e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain zinc_ribbon_15 PF17032.5 RLN93363.1 - 3.1e-05 24.6 1.0 8.3e-05 23.3 1.0 1.7 1 0 0 1 1 1 1 zinc-ribbon family DZR PF12773.7 RLN93363.1 - 8.1e-05 22.6 1.2 8.1e-05 22.6 1.2 2.0 2 0 0 2 2 2 1 Double zinc ribbon UPF0547 PF10571.9 RLN93363.1 - 0.00016 21.6 0.6 0.00042 20.3 0.6 1.7 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.6 RLN93363.1 - 0.00045 19.8 2.2 0.0012 18.5 2.2 1.8 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 RLN93363.1 - 0.0054 16.1 1.5 0.0054 16.1 1.5 2.4 3 0 0 3 3 3 1 zinc-ribbon domain APH PF01636.23 RLN93363.1 - 0.012 15.5 1.2 0.051 13.5 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 RLN93363.1 - 0.045 13.4 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family TF_Zn_Ribbon PF08271.12 RLN93363.1 - 0.11 12.1 0.8 0.39 10.3 0.8 2.0 1 0 0 1 1 1 0 TFIIB zinc-binding EcKinase PF02958.20 RLN93363.1 - 0.18 11.1 0.0 0.45 9.8 0.0 1.6 1 0 0 1 1 1 0 Ecdysteroid kinase zf-NADH-PPase PF09297.11 RLN93363.1 - 1.7 8.4 5.0 0.49 10.1 0.5 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Pyridoxal_deC PF00282.19 RLN93364.1 - 2.2e-61 207.7 0.0 2.7e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Phage_integrase PF00589.22 RLN93365.1 - 0.0059 16.4 0.0 0.045 13.5 0.0 2.4 2 1 0 2 2 2 1 Phage integrase family TRAM_LAG1_CLN8 PF03798.16 RLN93367.1 - 1.7e-25 90.0 15.6 2.4e-25 89.4 15.6 1.2 1 0 0 1 1 1 1 TLC domain TRAM_LAG1_CLN8 PF03798.16 RLN93368.1 - 4.9e-06 26.4 0.5 4.9e-06 26.4 0.5 1.6 2 0 0 2 2 2 1 TLC domain DUF2208 PF09973.9 RLN93368.1 - 6.9 6.2 9.5 0.32 10.6 0.5 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2208) Glyco_hydro_12 PF01670.16 RLN93371.1 - 4.3e-47 160.9 8.3 4.9e-47 160.7 8.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 OPA3 PF07047.12 RLN93372.1 - 2.3e-32 111.4 0.1 4.3e-32 110.5 0.1 1.4 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) HLH PF00010.26 RLN93374.1 - 0.064 13.2 3.3 0.13 12.3 3.3 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain LCD1 PF09798.9 RLN93374.1 - 0.067 11.7 0.0 0.067 11.7 0.0 1.4 2 0 0 2 2 2 0 DNA damage checkpoint protein MerR-DNA-bind PF09278.11 RLN93374.1 - 0.18 12.4 0.2 0.18 12.4 0.2 2.6 2 0 0 2 2 2 0 MerR, DNA binding DUF702 PF05142.12 RLN93374.1 - 0.3 11.5 2.0 71 3.9 2.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF702) SLX9 PF15341.6 RLN93374.1 - 1.4 9.3 8.9 0.092 13.1 3.0 1.9 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 APG6_N PF17675.1 RLN93374.1 - 1.9 9.0 8.6 4 8.0 0.5 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region CENP-H PF05837.12 RLN93374.1 - 6.6 7.2 7.2 2.9 8.4 0.3 2.5 3 0 0 3 3 3 0 Centromere protein H (CENP-H) FAM184 PF15665.5 RLN93374.1 - 8.5 6.1 9.0 0.61 9.8 3.3 1.8 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B RhoGAP PF00620.27 RLN93375.1 - 0.061 13.2 0.0 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 RhoGAP domain Exonuc_VII_L PF02601.15 RLN93377.1 - 0.17 11.4 14.0 0.29 10.6 14.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit OrfB_IS605 PF01385.19 RLN93377.1 - 3.6 7.8 8.7 1.4 9.1 0.2 2.7 3 0 0 3 3 3 0 Probable transposase GIT_CC PF16559.5 RLN93377.1 - 4.7 7.2 10.1 0.55 10.1 0.5 2.8 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor PRKG1_interact PF15898.5 RLN93377.1 - 5.9 7.9 18.0 0.17 12.8 2.1 2.5 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Methyltransf_16 PF10294.9 RLN93378.1 - 1.3e-23 83.6 0.0 1.9e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase DUF3320 PF11784.8 RLN93378.1 - 0.0079 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3320) UTP15_C PF09384.10 RLN93379.1 - 0.0083 15.8 1.1 0.012 15.4 0.1 1.7 2 0 0 2 2 2 1 UTP15 C terminal DUF4130 PF13566.6 RLN93379.1 - 0.26 11.3 1.2 0.44 10.6 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4130 Pkinase PF00069.25 RLN93380.1 - 3.4e-54 184.0 0.0 4.1e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN93380.1 - 5.1e-26 91.5 0.0 7.1e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN93380.1 - 0.00016 21.1 0.1 0.00025 20.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN93380.1 - 0.001 19.0 0.3 1.1 9.1 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN93380.1 - 0.027 13.3 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 RLN93380.1 - 0.047 13.0 0.0 6.4 6.0 0.0 2.3 1 1 0 2 2 2 0 Kinase-like Act-Frag_cataly PF09192.10 RLN93380.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic Choline_kinase PF01633.20 RLN93380.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pre-PUA PF17832.1 RLN93381.1 - 1.5e-10 41.6 0.2 2.5e-10 40.9 0.2 1.4 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 RLN93382.1 - 6.5e-13 48.5 0.1 2e-12 46.9 0.0 1.8 1 1 0 1 1 1 1 PUA domain Pre-PUA PF17832.1 RLN93382.1 - 6.1e-09 36.5 0.1 1e-08 35.7 0.1 1.4 1 0 0 1 1 1 1 Pre-PUA-like domain MatC_N PF07158.11 RLN93382.1 - 0.036 14.1 0.5 0.087 12.9 0.0 1.7 1 1 1 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus PDZ_6 PF17820.1 RLN93384.1 - 7.1e-10 38.6 0.1 3.3e-05 23.6 0.0 3.0 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 RLN93384.1 - 4.9e-09 36.4 0.0 0.00011 22.4 0.0 2.5 2 0 0 2 2 2 2 PDZ domain zinc_ribbon_4 PF13717.6 RLN93384.1 - 0.21 11.6 0.1 0.37 10.7 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Na_trans_assoc PF06512.13 RLN93384.1 - 7.7 6.7 16.5 17 5.6 16.5 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated WD40_4 PF16300.5 RLN93385.1 - 0.022 14.7 0.4 0.047 13.6 0.4 1.5 1 0 0 1 1 1 0 Type of WD40 repeat Tex_YqgF PF16921.5 RLN93385.1 - 0.16 12.4 0.0 0.25 11.8 0.0 1.2 1 0 0 1 1 1 0 Tex protein YqgF-like domain YL1 PF05764.13 RLN93385.1 - 2 8.5 3.9 2.3 8.3 3.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Ank_5 PF13857.6 RLN93388.1 - 1.4e-08 34.8 0.0 1.1e-07 32.0 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 RLN93388.1 - 6.2e-08 32.7 0.0 2.9e-05 24.3 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 RLN93388.1 - 9.8e-08 32.4 0.0 0.0043 17.6 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN93388.1 - 0.00014 22.0 0.0 0.072 13.7 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 RLN93388.1 - 0.0018 18.8 0.0 0.0082 16.7 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_2 PF12796.7 RLN93389.1 - 4.4e-77 254.7 24.8 4.9e-13 49.5 0.1 7.5 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN93389.1 - 5.7e-69 227.7 9.3 3e-09 37.2 0.0 10.1 4 3 6 11 11 11 10 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 RLN93389.1 - 3e-52 177.5 0.0 3.7e-41 141.1 0.0 3.4 2 1 0 2 2 2 2 Protein tyrosine kinase Ank PF00023.30 RLN93389.1 - 2e-51 170.3 29.7 0.00016 22.0 0.0 14.3 14 0 0 14 14 14 10 Ankyrin repeat Pkinase PF00069.25 RLN93389.1 - 2.7e-51 174.5 0.0 1.8e-39 135.7 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Ank_5 PF13857.6 RLN93389.1 - 1.5e-50 168.6 25.4 6.9e-07 29.4 0.2 13.1 1 1 12 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN93389.1 - 1.5e-44 144.9 9.2 0.037 14.6 0.0 14.3 14 0 0 14 14 14 11 Ankyrin repeat Pkinase_fungal PF17667.1 RLN93389.1 - 0.00053 18.9 0.0 0.0013 17.5 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase PK_C PF02887.16 RLN93389.1 - 0.004 17.4 7.4 7.2 6.9 0.3 4.8 3 2 1 4 4 4 1 Pyruvate kinase, alpha/beta domain APH PF01636.23 RLN93389.1 - 0.054 13.4 1.7 0.28 11.1 0.1 2.8 3 0 0 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 RLN93389.1 - 0.085 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family ABC_membrane PF00664.23 RLN93391.1 - 8.7e-47 160.0 20.3 1.2e-46 159.6 20.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN93391.1 - 1.8e-37 128.9 0.1 1.5e-34 119.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN93391.1 - 1.8e-07 30.8 3.0 0.039 13.4 0.0 3.4 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 RLN93391.1 - 0.0013 18.0 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin SbcCD_C PF13558.6 RLN93391.1 - 0.0029 17.8 2.5 2.2 8.6 0.3 4.0 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 RLN93391.1 - 0.0031 17.8 0.9 0.039 14.2 0.2 2.8 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 RLN93391.1 - 0.0048 16.6 0.1 0.011 15.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN93391.1 - 0.0058 17.0 1.2 0.018 15.4 1.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain DEAD PF00270.29 RLN93391.1 - 0.0091 15.8 0.0 0.089 12.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ABC_ATPase PF09818.9 RLN93391.1 - 0.011 14.6 0.2 0.03 13.1 0.0 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_21 PF13304.6 RLN93391.1 - 0.011 15.5 0.5 0.74 9.6 0.1 2.4 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RLN93391.1 - 0.019 14.7 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 RLN93391.1 - 0.046 13.8 0.1 0.14 12.2 0.0 1.8 2 0 0 2 2 1 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 RLN93391.1 - 0.047 13.6 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase G-alpha PF00503.20 RLN93391.1 - 0.057 12.6 0.0 0.28 10.3 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit AAA_25 PF13481.6 RLN93391.1 - 0.075 12.6 0.2 0.74 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 RLN93391.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Methyltransf_11 PF08241.12 RLN93392.1 - 3.1e-37 127.1 0.1 2.2e-20 73.1 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 RLN93392.1 - 9.3e-37 125.6 0.2 8.6e-21 74.5 0.0 3.1 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 RLN93392.1 - 3e-30 105.0 0.0 1.8e-21 76.6 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 RLN93392.1 - 3.5e-29 101.8 0.0 4.2e-20 72.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 RLN93392.1 - 4.5e-22 78.7 0.0 2.9e-13 50.4 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain CMAS PF02353.20 RLN93392.1 - 2e-21 76.5 0.1 3e-18 66.1 0.1 2.3 2 1 0 2 2 2 2 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 RLN93392.1 - 1.7e-18 66.8 0.0 1.1e-12 47.8 0.1 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 RLN93392.1 - 2.2e-12 46.9 0.0 3.5e-09 36.5 0.0 2.5 2 0 0 2 2 2 2 AdoMet dependent proline di-methyltransferase MTS PF05175.14 RLN93392.1 - 1.2e-10 41.2 0.0 0.00024 20.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain PCMT PF01135.19 RLN93392.1 - 3e-10 40.2 0.0 2.7e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.18 RLN93392.1 - 3.3e-09 36.5 0.0 0.0039 16.7 0.0 3.3 2 1 1 3 3 3 2 CheR methyltransferase, SAM binding domain TPMT PF05724.11 RLN93392.1 - 3.5e-08 33.4 0.0 0.00011 21.9 0.0 2.4 2 0 0 2 2 2 2 Thiopurine S-methyltransferase (TPMT) NodS PF05401.11 RLN93392.1 - 2.8e-07 30.4 0.0 0.00046 19.9 0.0 2.2 2 0 0 2 2 2 2 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 RLN93392.1 - 8.1e-07 28.3 0.0 5.7e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) MetW PF07021.12 RLN93392.1 - 3.5e-06 26.8 0.0 6.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.14 RLN93392.1 - 4.7e-06 26.1 0.0 0.0092 15.4 0.0 2.2 2 0 0 2 2 2 2 Tellurite resistance protein TehB RrnaAD PF00398.20 RLN93392.1 - 1.9e-05 23.8 0.0 0.021 13.9 0.0 2.3 2 0 0 2 2 2 2 Ribosomal RNA adenine dimethylase FtsJ PF01728.19 RLN93392.1 - 0.00015 21.9 0.1 0.36 10.9 0.1 2.6 2 1 0 2 2 2 2 FtsJ-like methyltransferase Bin3 PF06859.12 RLN93392.1 - 0.00045 20.8 0.1 0.19 12.4 0.0 2.9 2 2 0 2 2 2 1 Bicoid-interacting protein 3 (Bin3) PrmA PF06325.13 RLN93392.1 - 0.0011 18.4 0.0 0.022 14.1 0.0 2.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 RLN93392.1 - 0.002 18.2 0.0 0.007 16.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_29 PF03141.16 RLN93392.1 - 0.0021 16.7 0.0 0.011 14.4 0.0 2.0 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DOT1 PF08123.13 RLN93392.1 - 0.0028 17.2 0.3 0.0074 15.8 0.1 1.8 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 RLN93392.1 - 0.003 17.1 0.0 0.12 11.8 0.0 2.8 3 0 0 3 3 2 1 Putative methyltransferase Met_10 PF02475.16 RLN93392.1 - 0.013 15.2 0.0 0.65 9.7 0.0 2.4 2 0 0 2 2 2 0 Met-10+ like-protein tRNA_U5-meth_tr PF05958.11 RLN93392.1 - 0.13 11.3 0.0 0.43 9.5 0.0 1.7 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase Lzipper-MIP1 PF14389.6 RLN93393.1 - 0.07 13.4 1.0 0.5 10.7 0.7 2.3 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Lzipper-MIP1 PF14389.6 RLN93394.1 - 0.46 10.8 2.3 0.52 10.6 0.7 2.0 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Ribosomal_60s PF00428.19 RLN93394.1 - 2.7 8.7 8.8 5.9 7.6 8.8 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein ABC_tran PF00005.27 RLN93396.1 - 1.2e-51 174.9 0.0 1.7e-26 93.4 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN93396.1 - 2.9e-14 53.6 6.5 0.00084 19.2 0.1 4.0 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Acetyltransf_1 PF00583.25 RLN93396.1 - 6.7e-13 48.9 0.0 1.8e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family ABC_tran_Xtn PF12848.7 RLN93396.1 - 1.5e-12 47.4 7.1 1.2e-08 34.8 1.8 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN93396.1 - 2.7e-07 30.2 8.4 0.15 11.5 0.3 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain NB-ARC PF00931.22 RLN93396.1 - 6e-07 28.9 0.0 0.023 13.9 0.0 2.8 2 1 0 2 2 2 2 NB-ARC domain AAA_23 PF13476.6 RLN93396.1 - 2.2e-06 28.3 4.2 0.019 15.5 0.1 3.1 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 RLN93396.1 - 7.2e-06 25.7 1.1 0.049 13.4 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Acetyltransf_7 PF13508.7 RLN93396.1 - 2.6e-05 24.5 0.0 5.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RLN93396.1 - 3.5e-05 23.8 0.0 7.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_16 PF13191.6 RLN93396.1 - 4.8e-05 23.8 0.1 0.012 16.0 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 RLN93396.1 - 9.3e-05 23.0 0.7 0.043 14.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 RLN93396.1 - 0.00011 22.2 1.2 0.44 10.6 0.3 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase FR47 PF08445.10 RLN93396.1 - 0.00018 21.4 0.0 0.00055 19.9 0.0 1.9 1 0 0 1 1 1 1 FR47-like protein RsgA_GTPase PF03193.16 RLN93396.1 - 0.0011 18.9 0.4 1.9 8.3 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 RLN93396.1 - 0.0028 17.9 4.6 0.35 11.1 0.2 3.1 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 RLN93396.1 - 0.0044 16.6 0.1 0.21 11.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 RLN93396.1 - 0.0057 16.4 0.4 4.8 6.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 RLN93396.1 - 0.0069 16.6 1.1 11 6.4 0.0 4.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 RLN93396.1 - 0.008 16.2 0.2 0.96 9.5 0.0 3.0 3 1 0 3 3 2 1 AAA domain DLIC PF05783.11 RLN93396.1 - 0.0088 14.9 0.1 0.91 8.3 0.0 2.2 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) AAA_24 PF13479.6 RLN93396.1 - 0.01 15.6 0.8 1.4 8.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 RLN93396.1 - 0.018 13.8 3.0 1.4 7.5 0.1 3.1 4 0 0 4 4 4 0 AAA domain AAA_15 PF13175.6 RLN93396.1 - 0.019 14.7 0.0 5.9 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 RLN93396.1 - 0.021 15.2 0.0 2.6 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 RLN93396.1 - 0.027 14.9 1.5 4.2 7.8 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 RLN93396.1 - 0.046 13.6 1.0 4.5 7.2 0.1 2.8 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 RLN93396.1 - 0.055 13.6 0.4 2.7 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 RLN93396.1 - 0.055 13.0 0.3 2.7 7.5 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B ATPase_2 PF01637.18 RLN93396.1 - 0.065 13.1 0.1 0.63 9.9 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 RLN93396.1 - 0.066 13.1 0.0 15 5.4 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain YonK PF09642.10 RLN93396.1 - 0.094 12.9 0.0 0.45 10.7 0.0 2.1 2 0 0 2 2 1 0 YonK protein T2SSE PF00437.20 RLN93396.1 - 0.097 11.7 0.1 4.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.19 RLN93396.1 - 0.11 12.0 0.4 7.4 6.1 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 RLN93396.1 - 0.12 12.4 0.7 6.1 6.9 0.1 2.7 2 1 0 2 2 2 0 Dynamin family AAA_22 PF13401.6 RLN93396.1 - 0.15 12.3 1.7 12 6.2 0.0 3.5 3 1 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 RLN93396.1 - 0.16 12.4 0.1 8.8 6.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 RLN93396.1 - 0.18 12.1 0.9 16 5.8 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATPase PF06745.13 RLN93396.1 - 0.18 11.1 2.3 6.7 6.0 0.1 2.6 2 0 0 2 2 2 0 KaiC KAP_NTPase PF07693.14 RLN93396.1 - 0.19 11.0 0.0 7.1 5.8 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain ATP_bind_1 PF03029.17 RLN93396.1 - 0.66 9.7 2.6 6.8 6.4 0.0 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein GFO_IDH_MocA PF01408.22 RLN93397.1 - 9.1e-14 52.3 0.0 1.6e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 RLN93397.1 - 1.7e-06 28.1 0.0 4.1e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Gp_dh_N PF00044.24 RLN93397.1 - 0.0012 19.1 0.0 0.053 13.9 0.0 2.6 3 0 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 RLN93397.1 - 0.085 13.0 0.1 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Coprogen_oxidas PF01218.18 RLN93398.1 - 2e-136 453.6 0.0 2.3e-136 453.3 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase LIN52 PF10044.9 RLN93398.1 - 0.063 14.0 0.0 0.15 12.8 0.0 1.6 1 0 0 1 1 1 0 Retinal tissue protein Coprogen_oxidas PF01218.18 RLN93399.1 - 6.7e-127 422.3 0.0 8e-127 422.0 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase TFR_dimer PF04253.15 RLN93401.1 - 0.68 10.0 3.7 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain GPCR_chapero_1 PF11904.8 RLN93401.1 - 1 8.7 7.9 2.9 7.3 8.2 1.7 1 1 0 1 1 1 0 GPCR-chaperone DUF2730 PF10805.8 RLN93402.1 - 0.016 15.3 0.4 1.1 9.4 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) BST2 PF16716.5 RLN93402.1 - 0.12 13.0 2.2 0.3 11.7 0.6 2.1 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 OmpH PF03938.14 RLN93402.1 - 0.53 10.6 4.5 1.1 9.6 4.5 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DHHC PF01529.20 RLN93404.1 - 0.0072 16.4 0.7 0.011 15.9 0.1 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase PUF PF00806.19 RLN93405.1 - 1.4e-46 153.6 7.3 6.8e-06 25.5 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat zf-CCCH_4 PF18044.1 RLN93405.1 - 8.7e-07 28.6 4.7 2.6e-06 27.1 4.7 1.9 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 RLN93405.1 - 0.00034 20.5 6.5 0.00068 19.6 6.5 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 RLN93405.1 - 0.0013 18.6 4.5 0.0026 17.6 4.5 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 RLN93405.1 - 0.0038 17.9 1.4 0.01 16.5 1.4 1.7 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 RLN93405.1 - 0.16 12.5 4.9 0.32 11.5 4.9 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger TFIIF_alpha PF05793.12 RLN93405.1 - 1.9 6.9 6.3 3.8 6.0 6.3 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF747 PF05346.11 RLN93406.1 - 7.2e-96 321.4 21.0 8.8e-96 321.1 21.0 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family MORN PF02493.20 RLN93407.1 - 2e-40 134.3 59.9 1.9e-06 27.4 1.1 10.5 10 0 0 10 10 10 10 MORN repeat DUF3395 PF11875.8 RLN93408.1 - 1.5e-35 122.4 0.0 2.5e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 RLN93408.1 - 3e-14 52.9 0.1 5.2e-14 52.1 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF3034 PF11231.8 RLN93408.1 - 0.095 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3034) DUF3512 PF12024.8 RLN93408.1 - 0.16 11.4 0.4 1.1 8.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3512) PP2C PF00481.21 RLN93409.1 - 2.2e-30 106.1 0.0 3.4e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RLN93409.1 - 9.8e-06 25.3 0.0 9.3e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 RLN93409.1 - 0.02 14.8 0.3 0.074 13.0 0.1 2.0 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) PigN PF04987.14 RLN93410.1 - 3.7e-125 418.4 29.7 4.7e-125 418.0 29.7 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 RLN93410.1 - 3.7e-09 36.7 0.1 6e-06 26.1 0.2 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RLN93410.1 - 8.4e-06 25.4 0.1 1.4e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 RLN93410.1 - 0.0021 17.5 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily HEAT_2 PF13646.6 RLN93411.1 - 3.4e-06 27.4 4.5 0.0014 18.9 0.9 7.1 5 2 3 8 8 8 3 HEAT repeats HEAT_EZ PF13513.6 RLN93411.1 - 0.00041 20.8 33.8 0.098 13.2 0.3 8.7 8 1 1 9 9 9 3 HEAT-like repeat DUF4704 PF15787.5 RLN93411.1 - 0.0052 16.1 0.9 0.023 14.0 0.1 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4704) UME PF08064.13 RLN93411.1 - 0.0094 15.9 7.8 7.5 6.5 0.0 5.2 4 1 0 4 4 4 1 UME (NUC010) domain HEAT PF02985.22 RLN93411.1 - 0.02 15.1 14.5 0.71 10.3 0.1 7.3 6 1 0 6 6 6 0 HEAT repeat BP28CT PF08146.12 RLN93411.1 - 0.15 11.9 0.3 1.7 8.5 0.0 2.7 2 1 0 2 2 2 0 BP28CT (NUC211) domain Importin_rep_4 PF18808.1 RLN93411.1 - 0.18 12.1 5.0 0.36 11.1 0.0 3.8 3 1 0 3 3 3 0 Importin repeat CTD_bind PF04818.13 RLN93411.1 - 0.18 12.6 0.0 2.7 8.9 0.0 3.1 4 0 0 4 4 4 0 RNA polymerase II-binding domain. Sigma70_ner PF04546.13 RLN93411.1 - 1.1 9.0 9.9 0.24 11.3 1.9 2.5 3 0 0 3 3 3 0 Sigma-70, non-essential region TilS PF09179.11 RLN93411.1 - 2.4 8.7 12.1 5.1 7.7 0.1 4.8 5 1 0 5 5 5 0 TilS substrate binding domain RGS PF00615.19 RLN93412.1 - 8e-74 245.5 2.4 1.6e-19 70.3 0.0 4.3 4 0 0 4 4 4 4 Regulator of G protein signaling domain Nop25 PF09805.9 RLN93413.1 - 0.0042 17.6 7.3 0.0082 16.6 7.3 1.4 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) CALM_bind PF16025.5 RLN93413.1 - 0.059 13.8 4.4 0.15 12.5 4.4 1.7 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding dsDNA_bind PF01984.20 RLN93414.1 - 2.1e-16 60.2 2.3 3.5e-16 59.5 2.3 1.2 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Med4 PF10018.9 RLN93415.1 - 9.5e-09 35.2 1.1 9.5e-09 35.2 1.1 2.6 2 1 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 1-cysPrx_C PF10417.9 RLN93415.1 - 0.15 12.0 0.3 38 4.2 0.7 2.9 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin PPV_E2_N PF00508.17 RLN93415.1 - 0.42 9.9 1.9 0.72 9.2 1.3 1.6 2 0 0 2 2 2 0 E2 (early) protein, N terminal Peptidase_C1 PF00112.23 RLN93416.1 - 4e-45 154.6 1.4 5.6e-45 154.1 1.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RLN93416.1 - 0.0089 14.8 0.4 0.015 14.1 0.4 1.3 1 0 0 1 1 1 1 Peptidase C1-like family Abhydrolase_1 PF00561.20 RLN93417.1 - 4.8e-29 101.8 0.1 5e-27 95.2 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN93417.1 - 3.5e-22 80.1 0.1 4.6e-22 79.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN93417.1 - 6.2e-17 61.7 0.0 8.5e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 RLN93417.1 - 0.00021 20.1 0.2 0.0011 17.7 0.2 1.9 1 1 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.16 RLN93417.1 - 0.00058 19.7 0.0 0.0058 16.5 0.0 2.5 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 RLN93417.1 - 0.00099 19.1 0.0 0.0021 18.0 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 RLN93417.1 - 0.0021 17.7 0.1 0.033 13.7 0.1 2.5 2 1 0 2 2 2 1 Dienelactone hydrolase family Esterase PF00756.20 RLN93417.1 - 0.017 14.8 0.1 0.035 13.8 0.1 1.6 1 1 0 1 1 1 0 Putative esterase FSH1 PF03959.13 RLN93417.1 - 0.039 13.6 0.0 0.25 11.0 0.0 2.2 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Lipase PF00151.19 RLN93417.1 - 0.056 12.8 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipase DsrD PF08679.11 RLN93417.1 - 0.14 12.4 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) Abhydro_lipase PF04083.16 RLN93417.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Palm_thioest PF02089.15 RLN93417.1 - 0.18 11.6 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase ANAPC3 PF12895.7 RLN93418.1 - 0.013 15.7 0.1 0.029 14.6 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TRAP-gamma PF07074.12 RLN93418.1 - 0.058 13.0 0.3 0.082 12.5 0.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) eIF-3c_N PF05470.12 RLN93419.1 - 1.3e-152 509.2 38.5 2.9e-105 352.8 1.9 3.0 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 RLN93419.1 - 1e-10 42.0 0.1 5.6e-10 39.7 0.0 2.3 2 0 0 2 2 2 1 PCI domain DUF2204 PF09970.9 RLN93419.1 - 0.012 15.3 2.6 0.024 14.3 0.0 2.5 3 0 0 3 3 3 0 Nucleotidyl transferase of unknown function (DUF2204) Dsh_C PF12316.8 RLN93419.1 - 6.9 7.0 23.7 3.5 8.0 0.3 2.6 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Alba PF01918.21 RLN93420.1 - 4.2e-18 64.9 0.1 4.7e-17 61.6 0.1 2.2 2 0 0 2 2 2 1 Alba Rpp20 PF12328.8 RLN93420.1 - 2.3e-05 24.4 0.0 8.7e-05 22.5 0.0 2.1 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Lactamase_B_2 PF12706.7 RLN93421.1 - 1.3e-06 28.1 2.8 4.4e-06 26.4 0.3 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain PDEase_II PF02112.15 RLN93421.1 - 0.047 12.8 1.6 0.077 12.1 0.7 1.6 2 0 0 2 2 2 0 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 RLN93421.1 - 0.06 13.4 0.6 0.06 13.4 0.6 2.1 3 0 0 3 3 3 0 Metallo-beta-lactamase superfamily Atg8 PF02991.16 RLN93421.1 - 0.15 12.2 0.0 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Autophagy protein Atg8 ubiquitin like MFS_1 PF07690.16 RLN93422.1 - 1.7e-08 33.8 31.0 2.8e-05 23.2 14.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5337 PF17272.2 RLN93422.1 - 0.043 13.6 7.3 1.5 8.7 1.1 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5337) Peptidase_U4 PF03419.13 RLN93422.1 - 0.099 11.9 13.7 0.02 14.2 2.1 2.4 2 0 0 2 2 2 0 Sporulation factor SpoIIGA N_BRCA1_IG PF16158.5 RLN93423.1 - 4.7e-28 97.9 0.0 1.1e-27 96.8 0.0 1.6 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 RLN93423.1 - 1.6e-24 85.4 0.4 3e-11 42.9 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, ZZ type PB1 PF00564.24 RLN93423.1 - 1.3e-07 31.5 3.7 1.4e-07 31.3 0.1 2.5 3 0 0 3 3 3 1 PB1 domain UBA PF00627.31 RLN93423.1 - 2.7e-06 27.2 0.2 5.7e-06 26.1 0.2 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Collagen PF01391.18 RLN93423.1 - 1.1e-05 25.0 12.0 1.1e-05 25.0 12.0 4.5 2 1 0 3 3 3 1 Collagen triple helix repeat (20 copies) HOIP-UBA PF16678.5 RLN93423.1 - 0.15 12.0 1.5 0.24 11.4 0.2 2.0 2 0 0 2 2 2 0 HOIP UBA domain pair Abhydrolase_1 PF00561.20 RLN93424.1 - 2.8e-27 96.0 0.0 6.8e-20 71.8 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN93424.1 - 4.6e-21 76.4 0.0 5.6e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN93424.1 - 6e-15 55.2 0.0 7.5e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 RLN93424.1 - 0.00017 21.4 0.0 0.88 9.3 0.0 2.7 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Esterase PF00756.20 RLN93424.1 - 0.00023 20.9 0.0 0.00067 19.4 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Lipase PF00151.19 RLN93424.1 - 0.00044 19.7 0.0 0.0006 19.2 0.0 1.2 1 0 0 1 1 1 1 Lipase BAAT_C PF08840.11 RLN93424.1 - 0.00086 19.3 0.0 0.0023 17.9 0.0 1.6 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Palm_thioest PF02089.15 RLN93424.1 - 0.0028 17.5 0.0 0.0034 17.2 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase UPF0227 PF05728.12 RLN93424.1 - 0.0041 17.1 0.2 0.094 12.7 0.2 2.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) DLH PF01738.18 RLN93424.1 - 0.0053 16.3 0.1 3.1 7.3 0.1 2.6 2 1 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 RLN93424.1 - 0.015 14.8 0.0 0.89 9.0 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 RLN93424.1 - 0.016 15.1 0.1 0.045 13.6 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 RLN93424.1 - 0.019 14.7 0.0 1.4 8.7 0.0 2.4 1 1 0 2 2 2 0 Alpha/beta hydrolase family DUF900 PF05990.12 RLN93424.1 - 0.05 13.1 0.0 0.92 9.0 0.0 2.7 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 RLN93424.1 - 0.076 12.7 0.1 0.26 11.0 0.1 1.8 1 1 1 2 2 2 0 PGAP1-like protein ILVD_EDD PF00920.21 RLN93425.1 - 6.6e-188 625.5 2.6 6.8e-172 572.7 0.2 2.0 2 0 0 2 2 2 2 Dehydratase family FeoA PF04023.14 RLN93425.1 - 0.0027 17.9 0.0 1 9.7 0.0 2.7 2 0 0 2 2 2 2 FeoA domain TPK_catalytic PF04263.16 RLN93426.1 - 8.7e-39 132.3 0.4 1.1e-38 131.9 0.4 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 RLN93426.1 - 3e-17 62.1 0.0 4.5e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Mur_ligase_C PF02875.21 RLN93426.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Chorein_N PF12624.7 RLN93427.1 - 8.3e-23 80.7 0.0 3.2e-22 78.8 0.0 1.9 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 Lum_binding PF00677.17 RLN93428.1 - 5.9e-45 151.2 0.0 1e-21 76.7 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain COX15-CtaA PF02628.15 RLN93429.1 - 2.7e-31 108.8 2.9 4.4e-31 108.1 2.9 1.3 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Ribonuclease_T2 PF00445.18 RLN93429.1 - 2.3e-23 83.4 0.1 3.7e-23 82.7 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family DeoC PF01791.9 RLN93429.1 - 6.9e-17 61.8 4.7 1.1e-16 61.1 4.7 1.3 1 0 0 1 1 1 1 DeoC/LacD family aldolase His_biosynth PF00977.21 RLN93429.1 - 0.0095 15.4 0.1 0.02 14.3 0.1 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein FMN_dh PF01070.18 RLN93429.1 - 0.075 12.0 3.0 0.47 9.4 0.7 2.3 2 0 0 2 2 2 0 FMN-dependent dehydrogenase PreAtp-grasp PF18604.1 RLN93429.1 - 0.077 12.6 0.0 0.25 11.0 0.0 1.9 1 1 0 1 1 1 0 Pre ATP-grasp domain IMPDH PF00478.25 RLN93429.1 - 0.19 10.7 6.0 0.089 11.8 3.4 1.8 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain WD40 PF00400.32 RLN93430.1 - 6.5e-24 83.8 1.0 6.2e-11 42.7 0.0 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN93430.1 - 5.5e-07 29.8 0.0 0.009 16.3 0.0 2.9 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 RLN93430.1 - 0.024 13.2 0.0 0.029 12.9 0.0 1.1 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF5348 PF17295.2 RLN93430.1 - 0.058 13.3 0.0 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5348) ELYS-bb PF16687.5 RLN93430.1 - 0.13 10.9 0.0 4 6.0 0.0 2.0 1 1 1 2 2 2 0 beta-propeller of ELYS nucleoporin Nup160 PF11715.8 RLN93430.1 - 0.17 10.5 0.6 6.2 5.3 0.1 2.0 1 1 0 2 2 2 0 Nucleoporin Nup120/160 DnaJ PF00226.31 RLN93431.1 - 7.2e-13 48.5 0.2 7.2e-13 48.5 0.2 3.2 4 0 0 4 4 4 1 DnaJ domain Peptidase_U57 PF05582.12 RLN93431.1 - 0.75 9.0 11.8 13 5.0 9.3 2.3 2 0 0 2 2 2 0 YabG peptidase U57 FUSC PF04632.12 RLN93431.1 - 4.9 5.6 8.4 9.1 4.7 8.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ank_4 PF13637.6 RLN93432.1 - 4.4e-15 55.8 5.2 3.8e-05 24.2 0.0 4.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN93432.1 - 2.1e-14 53.8 4.0 1.4e-08 35.2 0.2 2.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN93432.1 - 1.3e-13 50.9 6.1 0.00059 20.1 0.0 5.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN93432.1 - 4.2e-08 32.8 0.2 5.4 7.9 0.0 6.2 5 1 1 6 6 6 2 Ankyrin repeat ARL2_Bind_BART PF11527.8 RLN93434.1 - 0.0087 16.2 1.5 0.012 15.7 1.5 1.2 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART ARL2_Bind_BART PF11527.8 RLN93435.1 - 0.00021 21.4 0.0 0.00025 21.1 0.0 1.0 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART LRR_4 PF12799.7 RLN93437.1 - 0.00013 22.3 9.2 0.0083 16.5 0.6 5.0 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RLN93437.1 - 0.0078 16.2 3.0 0.22 11.7 0.4 3.6 3 0 0 3 3 3 1 Leucine Rich repeat LRR_1 PF00560.33 RLN93437.1 - 1.3 9.9 10.5 7.2 7.6 0.1 5.1 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 RLN93437.1 - 2.9 7.7 10.3 1.6 8.6 0.4 4.3 4 1 1 5 5 5 0 Leucine rich repeat LRR_4 PF12799.7 RLN93438.1 - 8.8e-07 29.2 2.6 0.0067 16.8 0.1 4.8 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN93438.1 - 0.00017 21.6 0.6 1.3 9.8 0.0 4.9 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 RLN93438.1 - 0.00074 19.4 4.5 1.5 9.1 0.1 4.9 5 0 0 5 5 5 2 Leucine Rich repeat LRR_8 PF13855.6 RLN93438.1 - 0.0066 16.2 4.0 0.26 11.1 0.2 4.5 5 1 0 5 5 5 1 Leucine rich repeat LRR_12 PF18837.1 RLN93438.1 - 0.085 12.5 0.5 3.1 7.5 0.1 2.7 2 0 0 2 2 2 0 Leucine-rich repeat CWC25 PF12542.8 RLN93438.1 - 0.18 12.7 0.1 0.39 11.6 0.1 1.5 1 0 0 1 1 1 0 Pre-mRNA splicing factor Mcl1_mid PF12341.8 RLN93439.1 - 3.3e-55 187.5 0.0 8.4e-55 186.2 0.0 1.7 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 RLN93439.1 - 2.9e-05 24.3 0.0 1.1 9.6 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RLN93439.1 - 0.019 15.8 0.1 26 5.9 0.0 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat Spt5_N PF11942.8 RLN93439.1 - 1.1 10.3 10.6 2.8 9.0 10.6 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Thioredoxin PF00085.20 RLN93441.1 - 4.5e-05 23.4 0.1 5.5e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 RLN93441.1 - 0.00017 20.6 0.0 0.00018 20.6 0.0 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin_6 PF13848.6 RLN93441.1 - 0.014 15.3 0.0 0.017 15.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain EB1 PF03271.17 RLN93442.1 - 1.1e-15 57.6 0.4 2.5e-15 56.4 0.4 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 RLN93442.1 - 3.8e-08 33.5 0.1 6.4e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 RLN93442.1 - 0.097 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 CH-like domain in sperm protein Toxin_11 PF07473.11 RLN93443.1 - 1.4 9.1 6.6 4.7 7.4 6.6 2.0 1 0 0 1 1 1 0 Spasmodic peptide gm9a; conotoxin from Conus species Glu-tRNAGln PF02686.15 RLN93445.1 - 0.12 12.7 0.1 0.13 12.5 0.1 1.1 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit LSM PF01423.22 RLN93446.1 - 4.6e-22 77.5 0.1 5.4e-22 77.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 RLN93446.1 - 0.02 15.0 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 RimP C-terminal SH3 domain COMM_domain PF07258.14 RLN93447.1 - 1.9e-07 31.1 0.0 2.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 COMM domain Adaptin_N PF01602.20 RLN93448.1 - 2.9e-98 329.7 3.8 5.3e-89 299.2 0.4 2.0 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 RLN93448.1 - 5.3e-14 52.6 4.0 1e-10 41.9 0.0 4.0 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 RLN93448.1 - 0.0024 17.1 0.9 0.25 10.5 0.1 2.5 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain YL1 PF05764.13 RLN93448.1 - 0.0099 16.0 10.9 0.097 12.8 1.5 2.3 2 0 0 2 2 2 2 YL1 nuclear protein DM4_12 PF07841.13 RLN93448.1 - 0.065 13.9 0.0 0.28 11.9 0.0 2.1 1 0 0 1 1 1 0 DM4/DM12 family RTP1_C1 PF10363.9 RLN93448.1 - 0.076 13.2 1.8 95 3.2 0.0 4.5 4 1 1 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Cwf_Cwc_15 PF04889.12 RLN93448.1 - 0.25 11.1 9.3 0.69 9.6 2.2 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Spt5_N PF11942.8 RLN93448.1 - 0.45 11.5 15.0 0.11 13.5 5.4 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal B56 PF01603.20 RLN93448.1 - 1.2 8.0 3.8 0.32 9.9 0.5 1.7 2 0 0 2 2 2 0 Protein phosphatase 2A regulatory B subunit (B56 family) RXT2_N PF08595.11 RLN93448.1 - 1.9 8.5 8.1 1.6 8.8 0.2 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal FAM176 PF14851.6 RLN93448.1 - 9 5.9 13.6 7.2 6.3 2.0 2.5 2 0 0 2 2 2 0 FAM176 family Sigma70_ner PF04546.13 RLN93448.1 - 9.9 6.0 11.1 0.36 10.7 2.7 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Glu_cyclase_2 PF05096.12 RLN93449.1 - 5e-73 245.6 0.6 5.9e-72 242.1 0.6 1.9 1 1 0 1 1 1 1 Glutamine cyclotransferase PQQ_2 PF13360.6 RLN93449.1 - 0.037 13.6 0.3 1.3 8.6 0.2 2.6 1 1 1 2 2 2 0 PQQ-like domain NHL PF01436.21 RLN93449.1 - 0.17 11.9 0.7 20 5.5 0.1 3.7 4 0 0 4 4 4 0 NHL repeat DUF572 PF04502.13 RLN93450.1 - 3.2 7.3 33.4 4.3 6.9 33.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) AMPK1_CBM PF16561.5 RLN93452.1 - 1.4e-32 111.7 0.5 2.6e-32 110.9 0.5 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 RLN93452.1 - 2.1e-25 88.8 1.6 2.1e-25 88.8 1.6 1.7 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain Ost5 PF05251.12 RLN93453.1 - 7.6e-20 71.0 6.7 1.5e-19 70.0 6.7 1.5 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 CLASP_N PF12348.8 RLN93454.1 - 1.2e-05 25.0 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 RLN93454.1 - 0.053 13.8 0.3 1.8 9.1 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat Cnd3 PF12719.7 RLN93454.1 - 0.21 10.7 0.3 22 4.1 0.0 2.2 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain CENP-B_dimeris PF09026.10 RLN93454.1 - 6.3 7.3 9.3 39 4.7 8.2 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FAM176 PF14851.6 RLN93454.1 - 9.3 5.9 9.2 1.3 8.6 4.2 2.1 2 0 0 2 2 2 0 FAM176 family Pinin_SDK_memA PF04696.13 RLN93455.1 - 2.3e-25 89.2 13.7 2.3e-25 89.2 13.7 3.6 4 1 1 5 5 5 1 pinin/SDK/memA/ protein conserved region SAP PF02037.27 RLN93455.1 - 1.1e-11 44.2 3.2 1.1e-11 44.2 3.2 2.5 2 0 0 2 2 2 1 SAP domain HeH PF12949.7 RLN93455.1 - 0.15 11.8 1.2 1.3 8.8 0.0 2.8 3 0 0 3 3 3 0 HeH/LEM domain DUF4549 PF15082.6 RLN93455.1 - 1.2 9.0 8.6 4.1 7.2 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4549) Fib_alpha PF08702.10 RLN93455.1 - 1.4 9.1 10.5 0.22 11.7 0.6 3.0 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family B9-C2 PF07162.11 RLN93456.1 - 6.6e-36 124.0 0.0 8.8e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein CTP_transf_like PF01467.26 RLN93457.1 - 6.7e-26 91.2 0.0 1.1e-25 90.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like Rgp1 PF08737.10 RLN93458.1 - 4.6e-23 82.1 0.0 2.7e-14 53.2 0.0 3.3 3 1 0 3 3 3 2 Rgp1 Arrestin_C PF02752.22 RLN93458.1 - 0.0033 17.9 0.0 1 9.8 0.0 2.8 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 RLN93458.1 - 0.15 12.1 0.2 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Thioredoxin PF00085.20 RLN93459.1 - 1.2e-21 76.7 0.0 1.3e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 RLN93459.1 - 1.2e-05 25.7 0.2 0.00037 20.9 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RLN93459.1 - 4.4e-05 23.7 0.0 5.5e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 RLN93459.1 - 0.00013 21.5 0.0 0.00015 21.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 RLN93459.1 - 0.00023 21.3 0.1 0.00044 20.4 0.1 1.5 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.6 RLN93459.1 - 0.00027 20.7 0.0 0.00031 20.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 RLN93459.1 - 0.0031 17.4 0.0 0.0035 17.2 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 RLN93459.1 - 0.01 15.7 0.0 0.015 15.2 0.0 1.4 1 1 0 1 1 1 0 AhpC/TSA family DUF1281_C PF18406.1 RLN93459.1 - 0.057 13.1 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Ferredoxin-like domain in Api92-like protein Thioredoxin_3 PF13192.6 RLN93459.1 - 0.082 13.0 0.0 0.098 12.7 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin domain Redoxin PF08534.10 RLN93459.1 - 0.1 12.3 0.1 0.12 12.1 0.1 1.4 1 1 0 1 1 1 0 Redoxin Thioredoxin_7 PF13899.6 RLN93459.1 - 0.18 12.0 0.1 0.28 11.4 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like TMP-TENI PF02581.17 RLN93460.1 - 1.1e-38 132.4 0.0 2.9e-38 131.0 0.0 1.6 1 1 0 1 1 1 1 Thiamine monophosphate synthase PPI_Ypi1 PF07491.11 RLN93461.1 - 1.5e-16 59.9 1.9 1.7e-16 59.8 0.1 1.9 2 0 0 2 2 2 1 Protein phosphatase inhibitor Lipase_3 PF01764.25 RLN93462.1 - 2.2e-09 37.3 0.0 4.8e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 RLN93462.1 - 0.00071 20.2 1.1 0.0023 18.6 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN93462.1 - 0.0042 16.8 0.0 0.0088 15.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.8 RLN93462.1 - 0.0045 16.6 0.0 0.36 10.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) DUF2048 PF09752.9 RLN93462.1 - 0.0067 15.6 0.3 0.019 14.0 0.1 1.7 2 0 0 2 2 2 1 Abhydrolase domain containing 18 Hydrolase_4 PF12146.8 RLN93462.1 - 0.0084 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 UPF0227 PF05728.12 RLN93462.1 - 0.037 14.0 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 RLN93462.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family HKR_ArcB_TM PF18415.1 RLN93462.1 - 0.66 10.8 7.1 2.2 9.2 7.1 1.8 1 0 0 1 1 1 0 Histidine kinase receptor ArcB trans-membrane domain F5_F8_type_C PF00754.25 RLN93463.1 - 0.015 15.4 0.0 0.046 13.8 0.0 1.7 2 0 0 2 2 2 0 F5/8 type C domain DUF2322 PF10084.9 RLN93463.1 - 0.14 12.2 0.0 0.51 10.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2322) VEFS-Box PF09733.9 RLN93464.1 - 1.2e-07 31.6 0.2 2.3e-07 30.7 0.2 1.3 1 0 0 1 1 1 1 VEFS-Box of polycomb protein DUF4250 PF14056.6 RLN93465.1 - 0.001 19.0 0.1 0.0027 17.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4250) Med11 PF10280.9 RLN93465.1 - 0.019 15.5 0.8 0.08 13.4 0.1 2.2 2 0 0 2 2 2 0 Mediator complex protein ABC_tran_CTD PF16326.5 RLN93465.1 - 0.023 14.9 0.7 0.023 14.9 0.7 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain Pro_3_hydrox_C PF05373.11 RLN93465.1 - 0.048 13.8 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal Dscam_C PF12355.8 RLN93465.1 - 0.053 14.5 1.9 0.15 13.0 1.0 2.2 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal DUF5082 PF16888.5 RLN93465.1 - 0.08 13.2 0.6 0.23 11.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Prefoldin_2 PF01920.20 RLN93465.1 - 0.66 9.9 5.5 0.21 11.6 1.4 2.2 2 0 0 2 2 2 0 Prefoldin subunit UPF0242 PF06785.11 RLN93465.1 - 0.98 9.5 7.6 0.76 9.9 0.1 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF4200 PF13863.6 RLN93465.1 - 4.3 7.8 12.0 0.083 13.3 1.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) ASH PF15780.5 RLN93466.1 - 1.3e-11 44.5 0.6 9.9e-07 28.9 0.1 3.6 3 0 0 3 3 3 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 RLN93466.1 - 2e-06 27.6 0.1 8.2e-06 25.6 0.0 2.1 3 0 0 3 3 3 1 MSP (Major sperm protein) domain TMEM131_like PF12371.8 RLN93466.1 - 0.0018 18.5 0.3 0.092 13.0 0.0 2.7 2 0 0 2 2 2 1 Transmembrane protein 131-like RRM_3 PF08777.11 RLN93467.1 - 1.2e-18 67.1 4.7 2.4e-14 53.2 0.4 4.0 4 0 0 4 4 4 3 RNA binding motif La PF05383.17 RLN93467.1 - 1.5e-18 66.6 0.1 8.7e-18 64.1 0.0 2.3 2 0 0 2 2 2 1 La domain Mito_carr PF00153.27 RLN93468.1 - 1.9e-49 165.5 0.5 4.3e-19 68.2 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein HEAT PF02985.22 RLN93469.1 - 9.3e-13 47.3 4.5 0.0011 19.1 0.1 5.5 5 0 0 5 5 5 2 HEAT repeat WD40 PF00400.32 RLN93469.1 - 8.3e-10 39.1 1.0 1.6 9.8 0.0 6.5 7 1 0 7 7 7 3 WD domain, G-beta repeat HEAT_EZ PF13513.6 RLN93469.1 - 6.7e-08 32.9 1.1 0.001 19.5 0.0 4.0 5 0 0 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 RLN93469.1 - 2.2e-07 31.2 0.6 1.4e-05 25.4 0.0 3.6 4 1 1 5 5 5 1 HEAT repeats Cnd1 PF12717.7 RLN93469.1 - 7.1e-07 29.4 0.0 0.00042 20.4 0.0 3.0 1 1 2 3 3 3 3 non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 PF12894.7 RLN93469.1 - 8.2e-06 26.0 0.0 2.2 8.7 0.0 4.6 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4686 PF15742.5 RLN93470.1 - 0.052 12.7 61.2 0.29 10.2 24.1 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) Type2_restr_D3 PF16902.5 RLN93470.1 - 1.6 8.7 5.1 2.8 7.9 0.1 3.3 3 0 0 3 3 3 0 Type-2 restriction enzyme D3 domain GST_N_2 PF13409.6 RLN93471.1 - 3.3e-19 69.0 0.0 8.1e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN93471.1 - 1.7e-12 47.2 0.0 6.1e-12 45.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RLN93471.1 - 1e-08 35.2 0.0 1.8e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RLN93471.1 - 8.5e-06 26.1 0.0 0.022 15.1 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RLN93471.1 - 9.1e-06 25.8 0.1 1.9e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 RLN93471.1 - 0.00022 20.9 0.1 0.00041 20.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain She9_MDM33 PF05546.11 RLN93471.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family PX PF00787.24 RLN93472.1 - 2.7e-12 46.6 0.0 5e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 PX domain AA_permease_2 PF13520.6 RLN93473.1 - 4.1e-44 151.1 35.5 5.4e-44 150.7 35.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3040 PF11239.8 RLN93473.1 - 0.47 10.8 0.0 0.47 10.8 0.0 5.3 6 1 0 6 6 6 0 Protein of unknown function (DUF3040) Sec62 PF03839.16 RLN93474.1 - 1.2e-20 73.9 11.6 2e-20 73.2 11.6 1.3 1 0 0 1 1 1 1 Translocation protein Sec62 Cadherin_C_2 PF16492.5 RLN93474.1 - 0.64 10.8 5.0 7.4 7.4 5.1 2.3 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal MgtE PF01769.16 RLN93474.1 - 7.4 7.0 12.7 2.9 8.3 10.3 1.4 2 0 0 2 2 2 0 Divalent cation transporter Pur_ac_phosph_N PF16656.5 RLN93475.1 - 1.8e-18 66.9 0.1 4.7e-18 65.6 0.1 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 RLN93475.1 - 2.2e-12 47.6 0.1 6.5e-12 46.1 0.1 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 RLN93475.1 - 1.6e-11 45.1 4.9 2.8e-11 44.3 4.3 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Cyclin_C_2 PF16899.5 RLN93476.1 - 0.15 12.4 0.5 0.22 11.9 0.4 1.6 1 1 0 1 1 1 0 Cyclin C-terminal domain TauE PF01925.19 RLN93478.1 - 4.6e-22 78.8 34.4 3.8e-14 52.9 1.3 2.7 2 1 0 2 2 2 2 Sulfite exporter TauE/SafE SH3BGR PF04908.15 RLN93479.1 - 0.00045 20.3 0.1 0.00066 19.8 0.1 1.4 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 RLN93479.1 - 0.039 14.2 0.0 0.077 13.2 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin DUF5071 PF16804.5 RLN93480.1 - 0.034 14.4 0.2 2.2 8.5 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5071) HD-ZIP_N PF04618.12 RLN93480.1 - 0.095 13.2 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 HD-ZIP protein N terminus 2OG-FeII_Oxy_3 PF13640.6 RLN93481.1 - 0.00089 20.1 0.0 0.0022 18.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily T4SS_TraI PF16932.5 RLN93481.1 - 0.0044 16.2 0.3 0.26 10.4 0.1 2.3 2 0 0 2 2 2 2 Type IV secretory system, conjugal DNA-protein transfer GST_N PF02798.20 RLN93482.1 - 1.6e-22 79.6 0.0 3.7e-10 40.0 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RLN93482.1 - 3.1e-21 75.4 0.1 8.7e-14 51.5 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RLN93482.1 - 8.5e-10 38.9 0.0 0.00029 21.2 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN93482.1 - 7.6e-07 29.3 0.0 0.0096 16.2 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN93482.1 - 5e-05 23.2 0.1 0.0034 17.4 0.0 2.9 2 2 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RLN93482.1 - 0.0071 16.5 0.2 0.13 12.5 0.0 2.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 RLN93482.1 - 0.058 14.1 0.0 23 5.8 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain Peptidase_M50 PF02163.22 RLN93482.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M50 RPAP1_N PF08621.10 RLN93482.1 - 0.2 11.4 0.6 2.5 8.0 0.1 2.5 2 0 0 2 2 2 0 RPAP1-like, N-terminal GST_N PF02798.20 RLN93483.1 - 5.7e-15 55.4 0.0 5.4e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RLN93483.1 - 1.2e-12 47.8 0.0 1.3e-07 31.8 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RLN93483.1 - 2.5e-10 40.6 0.0 0.00046 20.6 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN93483.1 - 3.5e-05 24.0 0.0 0.16 12.3 0.0 2.7 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN93483.1 - 0.00011 22.2 0.0 0.00039 20.4 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HA2 PF04408.23 RLN93484.1 - 7.1e-22 77.7 0.0 1.5e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RLN93484.1 - 1.8e-17 63.5 0.0 3.5e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 RLN93484.1 - 4.7e-15 55.9 0.0 1.3e-14 54.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RLN93484.1 - 2.4e-08 34.0 0.2 6e-08 32.6 0.2 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 RLN93484.1 - 4.2e-05 23.5 0.1 0.00012 22.1 0.1 1.8 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_22 PF13401.6 RLN93484.1 - 8.8e-05 22.8 0.1 0.00048 20.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 RLN93484.1 - 0.0043 17.1 0.0 0.045 13.8 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RLN93484.1 - 0.0046 17.3 0.1 0.0096 16.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RLN93484.1 - 0.0049 16.6 0.1 0.0093 15.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 RLN93484.1 - 0.014 14.5 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 RLN93484.1 - 0.023 15.2 0.2 0.66 10.5 0.1 2.8 2 1 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 RLN93484.1 - 0.055 13.0 0.0 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 RLN93484.1 - 0.077 12.4 0.0 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein cobW PF02492.19 RLN93484.1 - 0.087 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 RLN93484.1 - 0.21 12.0 0.0 0.5 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain zf-Nse PF11789.8 RLN93485.1 - 3e-13 49.4 1.1 6.8e-13 48.2 1.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 RLN93485.1 - 0.0004 20.2 0.5 0.0017 18.2 0.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) BORCS7 PF16088.5 RLN93485.1 - 0.0011 19.2 0.1 0.0021 18.3 0.1 1.4 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 7 zf-RING_UBOX PF13445.6 RLN93485.1 - 0.0012 18.8 0.6 0.0023 17.9 0.6 1.4 1 0 0 1 1 1 1 RING-type zinc-finger ISG65-75 PF11727.8 RLN93485.1 - 0.0056 16.0 0.5 0.0077 15.5 0.5 1.2 1 0 0 1 1 1 1 Invariant surface glycoprotein zf-rbx1 PF12678.7 RLN93485.1 - 0.03 14.6 0.1 0.1 12.9 0.1 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-MIZ PF02891.20 RLN93485.1 - 0.033 13.9 0.3 0.033 13.9 0.3 1.7 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_2 PF13639.6 RLN93485.1 - 0.04 14.3 0.7 0.078 13.3 0.7 1.5 1 0 0 1 1 1 0 Ring finger domain Prp18 PF02840.15 RLN93485.1 - 0.25 11.4 1.1 0.34 10.9 0.3 1.6 2 0 0 2 2 2 0 Prp18 domain GST_C_3 PF14497.6 RLN93486.1 - 1.1e-19 70.4 0.0 1.1e-13 51.2 0.0 2.2 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RLN93486.1 - 9.9e-12 45.0 0.0 4e-06 27.1 0.0 3.3 3 1 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RLN93486.1 - 9.7e-05 22.5 0.0 0.002 18.3 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RLN93486.1 - 0.00018 21.4 0.0 0.03 14.4 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RLN93486.1 - 0.0034 17.8 0.0 13 6.3 0.0 3.5 2 1 1 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RLN93487.1 - 1.1e-22 80.2 0.0 3.7e-10 40.0 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RLN93487.1 - 3.5e-20 72.0 0.1 2.5e-12 46.9 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RLN93487.1 - 1.4e-09 38.2 0.0 0.00029 21.2 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN93487.1 - 1.4e-06 28.2 0.6 5.2e-05 23.2 0.0 2.9 3 1 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RLN93487.1 - 1.6e-06 28.3 0.0 0.021 15.1 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RLN93487.1 - 0.0033 17.6 0.2 0.07 13.4 0.0 2.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 RLN93487.1 - 0.023 15.4 0.0 9.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain Peptidase_M50 PF02163.22 RLN93487.1 - 0.083 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M50 bZIP_1 PF00170.21 RLN93488.1 - 3e-09 36.8 12.1 3.4e-09 36.7 9.3 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 RLN93488.1 - 1.3e-05 25.2 14.2 1.3e-05 25.2 14.2 1.8 2 0 0 2 2 2 1 Basic region leucine zipper SnoaL_2 PF12680.7 RLN93488.1 - 0.0026 18.4 0.0 0.0043 17.7 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain IZUMO PF15005.6 RLN93488.1 - 0.0028 18.2 0.2 0.0056 17.2 0.2 1.5 1 0 0 1 1 1 1 Izumo sperm-egg fusion, Ig domain-associated bZIP_Maf PF03131.17 RLN93488.1 - 0.0084 16.6 9.3 0.0084 16.6 9.3 1.9 1 1 1 2 2 2 1 bZIP Maf transcription factor Atg14 PF10186.9 RLN93488.1 - 0.023 13.8 4.9 0.028 13.5 4.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ribosomal_L35Ae PF01247.18 RLN93489.1 - 1.6e-42 143.5 1.1 1.9e-42 143.4 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 RLN93489.1 - 0.088 13.0 0.0 1.9 8.8 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain Cullin_Nedd8 PF10557.9 RLN93490.1 - 0.043 13.9 0.0 0.061 13.4 0.0 1.2 1 0 0 1 1 1 0 Cullin protein neddylation domain zf-BED PF02892.15 RLN93491.1 - 0.0029 17.6 0.1 0.0046 16.9 0.1 1.2 1 0 0 1 1 1 1 BED zinc finger RVT_1 PF00078.27 RLN93492.1 - 0.052 13.0 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) MIP PF00230.20 RLN93493.1 - 2.3e-51 174.7 5.8 3.3e-51 174.2 5.8 1.2 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 RLN93494.1 - 2.1e-50 171.5 5.7 2.9e-50 171.1 5.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein DctQ PF04290.12 RLN93494.1 - 0.026 14.4 0.5 0.026 14.4 0.5 2.0 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component MIP PF00230.20 RLN93495.1 - 9.9e-51 172.6 6.0 1.4e-50 172.2 6.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein DctQ PF04290.12 RLN93495.1 - 0.023 14.6 0.7 0.023 14.6 0.7 1.9 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component FYVE_2 PF02318.16 RLN93496.1 - 0.00017 21.8 5.3 0.00041 20.5 5.3 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 RLN93496.1 - 0.0002 21.4 12.9 0.00047 20.2 12.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 RLN93496.1 - 0.00061 20.4 0.1 0.0031 18.2 0.0 2.3 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 RLN93496.1 - 0.0008 19.7 0.0 0.0024 18.2 0.0 1.9 1 0 0 1 1 1 1 GAF domain zf-CRD PF17979.1 RLN93496.1 - 0.74 9.9 7.9 0.52 10.4 5.9 1.7 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions FYVE PF01363.21 RLN93497.1 - 9.7e-10 38.5 16.1 2.5e-09 37.1 16.1 1.7 1 0 0 1 1 1 1 FYVE zinc finger GAF_2 PF13185.6 RLN93497.1 - 3.7e-06 27.3 0.0 1.9e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 RLN93497.1 - 0.00013 22.6 0.1 0.00046 20.8 0.1 1.9 1 0 0 1 1 1 1 GAF domain FYVE_2 PF02318.16 RLN93497.1 - 0.0011 19.2 5.5 0.0011 19.2 5.5 2.1 2 0 0 2 2 2 1 FYVE-type zinc finger GAF_3 PF13492.6 RLN93497.1 - 0.036 14.4 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 GAF domain DUF4667 PF15700.5 RLN93497.1 - 0.057 13.5 1.9 0.089 12.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) NMD3 PF04981.13 RLN93497.1 - 0.3 10.5 6.7 0.66 9.4 6.7 1.5 1 1 0 1 1 1 0 NMD3 family Prok-RING_2 PF14445.6 RLN93497.1 - 0.65 10.2 6.9 2.4 8.4 6.9 2.1 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Prok-RING_4 PF14447.6 RLN93497.1 - 1.7 8.6 14.5 0.28 11.1 9.9 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 MIP PF00230.20 RLN93498.1 - 1e-50 172.5 5.8 1.4e-50 172.2 5.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF2157 PF09925.9 RLN93498.1 - 0.084 12.7 2.4 3.4 7.4 0.1 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF1418 PF07214.12 RLN93498.1 - 0.21 11.5 0.7 2.1 8.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) DctQ PF04290.12 RLN93498.1 - 0.25 11.3 5.7 0.053 13.4 0.7 2.2 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Polysacc_synt_C PF14667.6 RLN93498.1 - 5.3 7.1 9.2 0.97 9.5 0.6 2.7 2 1 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain MIP PF00230.20 RLN93499.1 - 1.1e-50 172.5 6.0 1.5e-50 172.1 6.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF2157 PF09925.9 RLN93499.1 - 0.021 14.6 0.4 3 7.6 0.0 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF1418 PF07214.12 RLN93499.1 - 0.2 11.5 0.7 2.1 8.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) DctQ PF04290.12 RLN93499.1 - 0.25 11.3 5.7 0.053 13.4 0.7 2.2 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Polysacc_synt_C PF14667.6 RLN93499.1 - 8.8 6.4 9.5 0.97 9.5 0.6 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain FXR_C1 PF16096.5 RLN93500.1 - 0.019 15.2 0.8 0.051 13.8 0.8 1.8 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 Mon2_C PF16206.5 RLN93501.1 - 3.3e-31 108.3 3.6 2.3e-29 102.2 1.8 3.0 2 1 0 2 2 2 2 C-terminal region of Mon2 protein Sec7_N PF12783.7 RLN93501.1 - 9.7e-16 58.1 1.4 1.6e-13 50.9 0.0 3.9 4 1 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 RLN93501.1 - 5.3e-05 23.0 0.0 0.0073 16.1 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) DCB PF16213.5 RLN93501.1 - 0.0025 17.5 0.8 0.013 15.2 0.1 2.6 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 DCB PF16213.5 RLN93502.1 - 4.8e-22 78.5 0.0 5.9e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 adh_short PF00106.25 RLN93505.1 - 5.3e-21 75.0 0.0 8.9e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN93505.1 - 3.3e-17 62.8 0.0 5e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HTH_Tnp_Tc5 PF03221.16 RLN93505.1 - 1.6e-09 37.6 0.0 3.9e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain RRM_1 PF00076.22 RLN93507.1 - 2e-12 46.8 0.4 3.6e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RLN93507.1 - 0.0093 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.6 RLN93507.1 - 0.022 14.4 0.3 0.06 13.0 0.0 1.8 2 0 0 2 2 2 0 Sporulation protein family 7 DUF4483 PF14825.6 RLN93508.1 - 2.6e-22 79.3 0.0 1.2e-14 54.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4483) PRKCSH-like PF12999.7 RLN93508.1 - 5.5e-19 68.6 1.2 1.5e-18 67.2 1.2 1.6 1 1 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 RLN93508.1 - 3.9e-16 59.1 0.8 2.4e-15 56.6 0.8 2.1 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF3015 PF11220.8 RLN93508.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) DDE_Tnp_1_7 PF13843.6 RLN93509.1 - 5e-18 65.5 0.4 1.2e-09 38.0 0.1 2.2 1 1 1 2 2 2 2 Transposase IS4 Dimer_Tnp_hAT PF05699.14 RLN93510.1 - 0.0017 18.1 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4420 PF14390.6 RLN93511.1 - 0.041 13.1 0.1 0.073 12.3 0.1 1.3 1 0 0 1 1 1 0 Putative PD-(D/E)XK family member, (DUF4420) CENP-H PF05837.12 RLN93511.1 - 0.074 13.5 8.4 0.38 11.2 2.4 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) FUSC PF04632.12 RLN93511.1 - 0.13 10.8 9.4 0.2 10.2 9.4 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family HR1 PF02185.16 RLN93511.1 - 0.22 11.7 8.2 0.11 12.6 3.8 2.6 2 0 0 2 2 2 0 Hr1 repeat GreA_GreB_N PF03449.15 RLN93511.1 - 0.64 10.2 8.0 0.057 13.6 2.5 2.1 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal CCDC-167 PF15188.6 RLN93511.1 - 5.4 7.4 7.8 0.25 11.7 0.5 2.5 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 FSH1 PF03959.13 RLN93512.1 - 9.5e-34 116.9 0.0 1.3e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) FSH1 PF03959.13 RLN93513.1 - 6.6e-33 114.2 0.0 8e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 RLN93513.1 - 0.01 16.4 0.1 0.013 16.1 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Palm_thioest PF02089.15 RLN93513.1 - 0.18 11.6 0.0 0.57 10.0 0.0 1.6 2 1 0 2 2 2 0 Palmitoyl protein thioesterase UCH PF00443.29 RLN93514.1 - 3.8e-55 187.2 0.0 6.3e-55 186.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN93514.1 - 4.1e-29 102.2 0.0 1.2e-28 100.7 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 RLN93514.1 - 0.00015 21.4 0.2 0.0085 15.8 0.0 2.9 2 0 0 2 2 2 1 Ubiquitin family UN_NPL4 PF11543.8 RLN93514.1 - 0.037 14.5 0.1 2 9.0 0.0 3.3 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 RA PF00788.23 RLN93514.1 - 0.31 11.7 1.6 6.9 7.4 0.1 3.7 4 0 0 4 4 4 0 Ras association (RalGDS/AF-6) domain USP7_C2 PF14533.6 RLN93514.1 - 0.66 9.6 4.6 9.6 5.8 0.2 3.1 3 1 0 3 3 3 0 Ubiquitin-specific protease C-terminal RXT2_N PF08595.11 RLN93514.1 - 5.2 7.1 6.9 3.3 7.7 0.8 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal KRE9 PF05390.11 RLN93515.1 - 0.077 13.7 0.0 0.2 12.4 0.0 1.7 1 0 0 1 1 1 0 Yeast cell wall synthesis protein KRE9/KNH1 DUF1729 PF08354.10 RLN93517.1 - 2.1e-132 441.3 0.0 5.7e-132 439.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) SAT PF16073.5 RLN93517.1 - 2.8e-30 105.8 0.5 5.9e-30 104.8 0.5 1.6 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 RLN93517.1 - 2.4e-28 99.6 0.5 1.3e-25 90.6 0.0 2.9 2 0 0 2 2 2 2 Acyl transferase domain MaoC_dehydratas PF01575.19 RLN93517.1 - 1.4e-18 66.6 0.0 4.1e-18 65.1 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain FAS_meander PF17951.1 RLN93517.1 - 9.8e-18 64.4 1.6 2.5e-17 63.1 0.0 2.4 3 0 0 3 3 3 1 Fatty acid synthase meander beta sheet domain TFIID_20kDa PF03847.13 RLN93517.1 - 0.11 12.9 0.0 0.37 11.3 0.0 1.8 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A tRNA-synt_2c PF01411.19 RLN93519.1 - 7.7e-156 519.8 0.0 1.1e-155 519.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 RLN93519.1 - 1.1e-10 41.4 0.1 2.3e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 RLN93519.1 - 3e-05 24.4 0.1 0.00029 21.3 0.2 2.4 2 0 0 2 2 2 1 DHHA1 domain tRNA-synt_2 PF00152.20 RLN93520.1 - 1.6e-97 326.4 0.0 2e-97 326.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RLN93520.1 - 5.5e-13 48.7 0.1 1.2e-12 47.6 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GAD PF02938.14 RLN93520.1 - 3.2e-12 46.5 0.5 6.7e-12 45.5 0.5 1.6 1 0 0 1 1 1 1 GAD domain tRNA-synt_2b PF00587.25 RLN93520.1 - 0.005 16.8 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 RLN93520.1 - 0.11 12.0 0.0 0.5 9.8 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) FLgD_tudor PF13861.6 RLN93521.1 - 0.11 12.8 9.0 1.5 9.1 3.5 2.7 1 1 1 2 2 2 0 FlgD Tudor-like domain WD40 PF00400.32 RLN93522.1 - 2.5e-06 28.1 0.3 0.017 16.0 0.1 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat Cupin_8 PF13621.6 RLN93523.1 - 6.7e-59 199.7 0.0 8.5e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 RLN93523.1 - 1.4e-05 24.8 0.0 0.1 12.1 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein Sigma70_ner PF04546.13 RLN93523.1 - 1.5 8.7 10.3 3 7.7 10.3 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region TPR_2 PF07719.17 RLN93524.1 - 1.7e-30 102.7 15.6 2.5e-07 30.3 0.0 8.0 7 1 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 RLN93524.1 - 2e-30 103.3 21.3 6.5e-08 32.1 0.2 8.3 8 1 0 8 8 7 5 Tetratricopeptide repeat DnaJ PF00226.31 RLN93524.1 - 1.2e-24 86.2 2.6 3.9e-24 84.5 2.6 2.0 1 0 0 1 1 1 1 DnaJ domain TPR_16 PF13432.6 RLN93524.1 - 5.5e-21 74.9 8.2 1.6e-05 25.5 0.0 5.1 4 1 0 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN93524.1 - 9e-21 73.3 15.6 0.00012 21.7 1.2 7.6 4 3 3 7 7 7 5 TPR repeat TPR_19 PF14559.6 RLN93524.1 - 7.4e-16 58.4 13.3 4.2e-07 30.4 0.0 6.1 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 RLN93524.1 - 5.9e-14 51.4 8.9 0.0001 22.4 0.1 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN93524.1 - 5.5e-13 48.0 11.7 0.00063 19.8 0.1 7.5 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN93524.1 - 2.8e-11 43.5 17.6 0.00064 20.0 2.1 5.4 5 2 0 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN93524.1 - 2.9e-11 42.6 8.5 0.088 12.9 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 RLN93524.1 - 1.7e-10 40.8 18.2 0.029 15.2 0.0 8.5 7 2 2 9 9 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN93524.1 - 4.3e-07 30.1 12.5 0.00012 22.2 0.1 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 RLN93524.1 - 1.1e-06 28.6 7.4 3e-05 24.1 0.1 4.2 4 2 0 4 4 3 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 RLN93524.1 - 9.7e-06 25.6 4.4 0.074 13.1 0.0 3.6 2 1 1 3 3 3 2 Putative TPR-like repeat BTAD PF03704.17 RLN93524.1 - 6e-05 23.5 7.3 0.45 10.9 1.3 5.0 1 1 4 5 5 5 3 Bacterial transcriptional activator domain TPR_6 PF13174.6 RLN93524.1 - 0.00014 22.3 17.7 0.038 14.6 0.1 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN93524.1 - 0.00079 19.2 6.4 0.044 13.7 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 RLN93524.1 - 0.002 17.4 0.4 0.11 11.7 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 RLN93524.1 - 0.0033 16.8 1.9 2.3 7.5 0.0 3.1 3 0 0 3 3 3 2 MalT-like TPR region DUF3856 PF12968.7 RLN93524.1 - 0.0075 16.3 2.8 0.12 12.4 0.5 3.9 4 1 0 4 4 3 1 Domain of Unknown Function (DUF3856) HrpB1_HrpK PF09613.10 RLN93524.1 - 0.013 15.2 0.1 0.054 13.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) Coatomer_E PF04733.14 RLN93524.1 - 0.014 14.9 0.1 0.048 13.1 0.0 2.0 1 1 0 1 1 1 0 Coatomer epsilon subunit FAT PF02259.23 RLN93524.1 - 0.036 13.3 1.0 0.14 11.4 0.5 2.1 2 1 0 2 2 2 0 FAT domain HEAT_2 PF13646.6 RLN93524.1 - 0.044 14.2 1.1 0.88 10.0 0.0 3.4 3 1 1 4 4 3 0 HEAT repeats EccE PF11203.8 RLN93524.1 - 0.067 13.5 0.2 0.27 11.6 0.2 2.1 1 0 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE MIT PF04212.18 RLN93524.1 - 0.11 12.6 13.7 0.84 9.7 0.3 5.6 5 1 1 6 6 5 0 MIT (microtubule interacting and transport) domain DUF148 PF02520.17 RLN93524.1 - 0.15 12.2 0.8 0.6 10.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF148 Fis1_TPR_C PF14853.6 RLN93524.1 - 0.59 10.3 5.6 9.8 6.3 0.0 4.3 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 RLN93524.1 - 1 10.2 0.0 1 10.2 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 RLN93525.1 - 4.8e-24 85.4 0.0 3e-23 82.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN93525.1 - 1.2e-19 71.8 1.9 1.7e-19 71.3 1.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN93525.1 - 1.5e-06 27.7 0.0 2.7e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 RLN93525.1 - 4.4e-05 23.8 0.2 9.7e-05 22.7 0.2 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 RLN93526.1 - 2.9e-09 36.9 0.0 3.5e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN93526.1 - 0.0026 18.4 0.1 0.0034 18.0 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 RLN93526.1 - 0.0032 17.6 0.0 0.0049 17.0 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein UCH PF00443.29 RLN93527.1 - 3.5e-56 190.6 0.0 4.8e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN93527.1 - 3.2e-19 69.7 0.0 9.8e-19 68.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DNA_RNApol_7kD PF03604.13 RLN93527.1 - 5.9 6.7 7.3 11 5.8 1.6 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit HSP70 PF00012.20 RLN93528.1 - 3e-225 749.0 7.8 3.6e-225 748.7 7.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN93528.1 - 2.2e-13 49.7 0.0 4.4e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 RLN93528.1 - 0.15 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain MecA_N PF05223.11 RLN93530.1 - 0.039 14.2 0.4 0.039 14.2 0.4 1.9 2 0 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain Utp14 PF04615.13 RLN93530.1 - 0.12 10.9 37.6 0.14 10.7 37.6 1.0 1 0 0 1 1 1 0 Utp14 protein FAIM1 PF06905.13 RLN93531.1 - 9.8e-05 22.1 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) zf-RanBP PF00641.18 RLN93531.1 - 0.016 14.5 0.9 0.04 13.2 0.9 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others CBM_35 PF16990.5 RLN93531.1 - 0.15 12.4 0.1 0.28 11.5 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate binding module (family 35) Gln-synt_C PF00120.24 RLN93532.1 - 9.1e-17 61.1 0.0 9.8e-16 57.7 0.0 2.2 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 RLN93532.1 - 9.6e-14 50.9 0.0 1.6e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain bPH_1 PF08000.11 RLN93534.1 - 5.8e-20 71.6 0.1 8.2e-20 71.1 0.1 1.2 1 0 0 1 1 1 1 Bacterial PH domain bPH_1 PF08000.11 RLN93535.1 - 2.2e-20 73.0 0.2 2.9e-20 72.6 0.2 1.1 1 0 0 1 1 1 1 Bacterial PH domain ISP3_C PF18045.1 RLN93535.1 - 0.1 12.5 0.2 9.7 6.1 0.0 2.1 2 0 0 2 2 2 0 ISP3 C-terminal Pkinase_Tyr PF07714.17 RLN93536.1 - 2.3e-38 132.0 0.0 3.7e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN93536.1 - 1.5e-32 113.0 0.0 2.8e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RLN93536.1 - 0.0041 16.5 0.0 0.011 15.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 RLN93536.1 - 0.15 12.0 1.7 0.69 9.8 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family GAF PF01590.26 RLN93537.1 - 0.00058 20.5 0.0 0.00084 20.0 0.0 1.3 1 0 0 1 1 1 1 GAF domain C2 PF00168.30 RLN93538.1 - 8.8e-16 58.1 0.0 2.3e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 C2 domain SMP_LBD PF17047.5 RLN93538.1 - 1.7e-14 53.7 0.2 2.9e-14 52.9 0.2 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain DUF4381 PF14316.6 RLN93538.1 - 0.07 13.4 0.8 0.17 12.2 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) MDD_C PF18376.1 RLN93539.1 - 9e-51 172.3 0.0 1.1e-50 172.0 0.0 1.1 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain HSP70 PF00012.20 RLN93540.1 - 1.3e-14 53.3 0.0 1.5e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein SOUL PF04832.12 RLN93541.1 - 0.069 13.3 2.2 0.075 13.2 2.2 1.1 1 0 0 1 1 1 0 SOUL heme-binding protein Pox_Ag35 PF03286.14 RLN93541.1 - 7.2 6.3 14.0 7.8 6.2 14.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CorA PF01544.18 RLN93543.1 - 1.5e-50 172.2 0.0 1.1e-42 146.3 0.0 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein EF-hand_7 PF13499.6 RLN93543.1 - 0.0007 20.0 0.2 0.0044 17.4 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN93543.1 - 0.0023 17.3 0.1 0.0076 15.7 0.1 2.0 1 0 0 1 1 1 1 EF hand ATP_bind_2 PF03668.15 RLN93543.1 - 0.003 16.9 0.1 0.005 16.2 0.1 1.2 1 0 0 1 1 1 1 P-loop ATPase protein family EF-hand_8 PF13833.6 RLN93543.1 - 0.073 12.9 0.0 0.073 12.9 0.0 2.2 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_6 PF13405.6 RLN93543.1 - 0.11 12.5 0.0 0.43 10.7 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 RLN93543.1 - 0.3 10.7 1.0 0.77 9.4 0.1 2.1 2 0 0 2 2 2 0 EF hand Pkinase PF00069.25 RLN93544.1 - 9.2e-50 169.4 0.0 1e-49 169.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN93544.1 - 2.5e-30 105.6 0.0 3.6e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN93544.1 - 8.9e-06 24.7 0.0 1.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN93544.1 - 0.00016 21.1 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 RLN93544.1 - 0.0016 18.1 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 RLN93544.1 - 0.0021 18.0 0.7 0.082 12.8 0.3 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN93544.1 - 0.024 14.0 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 RLN93545.1 - 2.1e-47 161.7 0.0 2.7e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN93545.1 - 5.5e-29 101.2 0.0 8.1e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN93545.1 - 0.00097 18.0 0.0 0.0016 17.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 RLN93545.1 - 0.0055 15.7 0.0 0.014 14.3 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 RLN93545.1 - 0.0078 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family MEA1 PF06910.11 RLN93545.1 - 0.0091 16.6 0.8 0.016 15.8 0.8 1.3 1 0 0 1 1 1 1 Male enhanced antigen 1 (MEA1) APH PF01636.23 RLN93545.1 - 0.011 15.6 0.3 0.12 12.2 0.3 2.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN93545.1 - 0.058 12.7 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FYVE PF01363.21 RLN93549.1 - 1.7e-09 37.7 14.3 1.7e-09 37.7 14.3 2.1 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 RLN93549.1 - 0.0071 16.5 6.8 0.019 15.2 6.8 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger Cytochrom_C550 PF14495.6 RLN93549.1 - 0.024 14.4 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c-550 domain AMP-binding PF00501.28 RLN93550.1 - 1.5e-10 40.3 0.0 2.6e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme TetR_C_14 PF17754.1 RLN93550.1 - 0.011 15.7 0.8 0.02 14.8 0.8 1.4 1 0 0 1 1 1 0 MftR C-terminal domain PQQ_3 PF13570.6 RLN93551.1 - 3e-27 94.4 12.0 2.2e-06 27.9 0.1 8.3 8 1 0 8 8 8 6 PQQ-like domain PQQ_2 PF13360.6 RLN93551.1 - 5.7e-26 91.5 0.8 1.3e-15 57.6 0.3 2.5 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.21 RLN93551.1 - 1.9e-24 84.3 2.7 2.6e-08 33.4 0.2 6.5 6 0 0 6 6 6 4 PQQ enzyme repeat SUKH-4 PF14435.6 RLN93551.1 - 0.079 13.0 6.3 3.2 7.8 0.1 3.8 2 1 2 4 4 4 0 SUKH-4 immunity protein Toxin_ToxA PF11584.8 RLN93551.1 - 0.14 12.2 0.1 15 5.6 0.0 2.6 2 0 0 2 2 2 0 Proteinaceous host-selective toxin ToxA DSPc PF00782.20 RLN93552.1 - 6.1e-21 74.6 0.0 8.4e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Peptidase_S28 PF05577.12 RLN93553.1 - 1.1e-109 367.2 0.0 1.2e-109 367.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 RLN93553.1 - 0.0038 16.7 0.1 0.0062 16.0 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PsaA_PsaB PF00223.19 RLN93553.1 - 0.095 10.9 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein eIF-3_zeta PF05091.12 RLN93554.1 - 6.3e-188 626.0 0.0 7.2e-188 625.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RE_LlaMI PF09562.10 RLN93555.1 - 0.13 11.9 0.0 0.15 11.6 0.0 1.0 1 0 0 1 1 1 0 LlaMI restriction endonuclease DUF2439 PF10382.9 RLN93556.1 - 7.8e-11 42.2 0.1 1e-10 41.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Orai-1 PF07856.12 RLN93557.1 - 3e-31 108.4 4.6 4.5e-31 107.9 4.6 1.2 1 0 0 1 1 1 1 Mediator of CRAC channel activity Jiraiya PF15038.6 RLN93557.1 - 0.11 11.9 10.4 0.61 9.5 10.4 2.1 1 1 0 1 1 1 0 Jiraiya Beta-lactamase PF00144.24 RLN93558.1 - 2.5e-33 115.7 0.1 3.9e-33 115.1 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF2239 PF09998.9 RLN93558.1 - 0.12 12.1 0.3 0.2 11.4 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2239) 4HBT PF03061.22 RLN93559.1 - 1.8e-14 53.9 0.3 5.4e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily DUF1409 PF07197.12 RLN93559.1 - 0.0035 17.2 0.4 0.1 12.5 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1409) tRNA_bind PF01588.20 RLN93560.1 - 9.8e-20 70.5 0.4 1.3e-19 70.0 0.4 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain HMG_CoA_synt_C PF08540.10 RLN93561.1 - 6.2e-52 177.0 0.1 1.4e-51 175.8 0.1 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal GMC_oxred_N PF00732.19 RLN93561.1 - 1.7e-22 80.1 0.0 3.8e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase HMG_CoA_synt_N PF01154.17 RLN93561.1 - 6.2e-17 62.0 0.6 1.6e-14 54.2 0.0 2.7 3 0 0 3 3 3 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ketoacyl-synt PF00109.26 RLN93561.1 - 5.1e-15 55.7 6.1 1.6e-14 54.1 6.1 1.9 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain GMC_oxred_C PF05199.13 RLN93561.1 - 3.4e-10 40.6 0.3 8.1e-10 39.4 0.3 1.7 1 0 0 1 1 1 1 GMC oxidoreductase ACP_syn_III PF08545.10 RLN93561.1 - 1.9e-07 30.8 1.7 9.5e-07 28.6 0.8 2.4 1 1 1 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NAD_binding_8 PF13450.6 RLN93561.1 - 7.5e-06 26.1 4.5 1.3e-05 25.3 0.0 3.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 RLN93561.1 - 8.9e-06 25.0 0.1 0.0034 16.5 0.0 2.5 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 RLN93561.1 - 0.00019 20.8 0.5 0.00068 19.0 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 RLN93561.1 - 0.0015 17.8 0.3 0.0029 16.9 0.3 1.4 1 0 0 1 1 1 1 Thi4 family PX PF00787.24 RLN93561.1 - 0.0022 17.9 0.0 0.0051 16.8 0.0 1.6 1 0 0 1 1 1 1 PX domain FAD_binding_3 PF01494.19 RLN93561.1 - 0.0038 16.5 0.3 0.0089 15.3 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 RLN93561.1 - 0.012 14.4 0.1 0.025 13.3 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein ACP_syn_III_C PF08541.10 RLN93561.1 - 0.059 13.5 0.1 0.2 11.8 0.1 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Trp_halogenase PF04820.14 RLN93561.1 - 0.084 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase DAO PF01266.24 RLN93561.1 - 0.099 12.2 1.1 0.29 10.7 0.5 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 RLN93561.1 - 0.19 10.7 1.7 0.18 10.8 0.4 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein PTP_tm PF18861.1 RLN93562.1 - 0.005 16.9 1.9 0.0093 16.0 1.4 1.7 1 1 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J TMEM154 PF15102.6 RLN93562.1 - 0.005 16.7 3.5 0.005 16.7 3.5 3.8 1 1 1 2 2 2 1 TMEM154 protein family PsbX PF06596.11 RLN93562.1 - 0.0071 16.3 0.3 0.019 14.9 0.3 1.7 1 0 0 1 1 1 1 Photosystem II reaction centre X protein (PsbX) Utp14 PF04615.13 RLN93562.1 - 0.069 11.7 20.6 0.081 11.5 20.6 1.2 1 0 0 1 1 1 0 Utp14 protein EphA2_TM PF14575.6 RLN93562.1 - 0.11 13.4 1.3 0.39 11.6 0.0 2.4 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Coilin_N PF15862.5 RLN93562.1 - 0.2 11.5 8.2 1.2 9.0 8.1 2.5 1 1 0 1 1 1 0 Coilin N-terminus Mitofilin PF09731.9 RLN93562.1 - 0.36 9.6 15.6 0.48 9.2 15.6 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Orf78 PF06024.12 RLN93562.1 - 0.55 10.6 3.6 90 3.5 3.6 3.2 1 1 0 1 1 1 0 Orf78 (ac78) DUF4648 PF15505.6 RLN93562.1 - 1.2 10.1 3.7 2 9.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4648) PepSY_TM PF03929.16 RLN93562.1 - 5.7 6.5 9.5 0.71 9.5 4.0 2.4 1 1 1 2 2 2 0 PepSY-associated TM region CNOT11 PF10155.9 RLN93563.1 - 2.6e-39 134.2 6.0 4.1e-39 133.6 6.0 1.2 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 WW PF00397.26 RLN93563.1 - 0.11 12.6 0.2 0.11 12.6 0.2 1.9 2 0 0 2 2 2 0 WW domain Creb_binding PF09030.10 RLN93563.1 - 0.28 11.9 1.4 0.53 11.0 0.1 2.0 2 0 0 2 2 2 0 Creb binding Q_salvage PF10343.9 RLN93564.1 - 8e-20 71.6 0.0 8.2e-10 38.7 0.0 2.5 1 1 1 2 2 2 2 Potential Queuosine, Q, salvage protein family Glyco_hydro_7 PF00840.20 RLN93565.1 - 1.8e-79 267.5 0.6 2.5e-79 267.1 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Mito_carr PF00153.27 RLN93565.1 - 2.6e-25 88.1 7.6 9.4e-12 44.7 0.0 3.8 4 0 0 4 4 4 3 Mitochondrial carrier protein ARGLU PF15346.6 RLN93565.1 - 0.0026 17.7 7.8 0.0039 17.1 7.8 1.2 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 SPX PF03105.19 RLN93565.1 - 0.01 15.8 4.0 0.015 15.3 4.0 1.1 1 0 0 1 1 1 0 SPX domain PKcGMP_CC PF16808.5 RLN93565.1 - 0.11 12.3 2.9 0.19 11.6 2.9 1.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase NAM-associated PF14303.6 RLN93565.1 - 0.12 13.1 4.0 0.46 11.2 4.0 2.1 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain NACHT PF05729.12 RLN93565.1 - 0.14 12.1 0.7 0.85 9.5 0.7 2.1 1 1 0 1 1 1 0 NACHT domain Hamartin PF04388.12 RLN93565.1 - 0.42 9.2 9.4 0.6 8.7 9.4 1.1 1 0 0 1 1 1 0 Hamartin protein PhoU PF01895.19 RLN93565.1 - 0.44 11.0 1.9 0.86 10.1 1.9 1.4 1 0 0 1 1 1 0 PhoU domain Med13_C PF06333.12 RLN93565.1 - 0.48 9.6 7.0 0.75 9.0 7.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain SOG2 PF10428.9 RLN93565.1 - 6.2 5.9 13.5 8.9 5.4 13.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Exo_endo_phos PF03372.23 RLN93566.1 - 1.2e-08 34.8 0.0 2.7e-08 33.6 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MORN PF02493.20 RLN93566.1 - 2.6e-05 23.9 3.2 0.0003 20.5 0.2 3.0 3 0 0 3 3 3 1 MORN repeat TolA_bind_tri PF16331.5 RLN93566.1 - 0.0016 18.5 1.4 0.0037 17.3 1.4 1.6 1 0 0 1 1 1 1 TolA binding protein trimerisation Exo_endo_phos_2 PF14529.6 RLN93566.1 - 0.14 12.0 0.0 4.1 7.3 0.0 2.7 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase KLRAQ PF10205.9 RLN93566.1 - 0.15 12.3 7.5 0.034 14.4 2.9 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein DivIC PF04977.15 RLN93566.1 - 0.23 11.3 1.4 0.65 9.8 1.4 1.8 1 0 0 1 1 1 0 Septum formation initiator DUF3682 PF12446.8 RLN93566.1 - 0.44 11.0 4.0 0.97 9.9 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) PAXIP1_C PF15364.6 RLN93567.1 - 0.0052 17.1 6.7 0.16 12.3 0.9 2.5 1 1 1 2 2 2 2 PAXIP1-associated-protein-1 C term PTIP binding protein CNF1 PF05785.12 RLN93567.1 - 0.0081 15.5 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 Rho-activating domain of cytotoxic necrotizing factor Orai-1 PF07856.12 RLN93568.1 - 1.8e-09 37.5 0.0 3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Mediator of CRAC channel activity Synaphin PF05835.12 RLN93568.1 - 0.049 13.9 1.1 0.06 13.6 1.1 1.1 1 0 0 1 1 1 0 Synaphin protein TMEM237 PF15383.6 RLN93568.1 - 0.055 12.6 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 AA_kinase PF00696.28 RLN93569.1 - 3e-39 135.0 0.2 6e-39 134.1 0.2 1.5 1 0 0 1 1 1 1 Amino acid kinase family Homoserine_dh PF00742.19 RLN93569.1 - 3.5e-24 85.6 0.0 7.5e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase ACT_7 PF13840.6 RLN93569.1 - 2.3e-12 46.5 1.0 1.8e-07 30.9 0.0 2.9 2 0 0 2 2 2 2 ACT domain Orai-1 PF07856.12 RLN93569.1 - 1.1e-11 44.7 2.8 2.3e-11 43.7 2.8 1.5 1 0 0 1 1 1 1 Mediator of CRAC channel activity ACT PF01842.25 RLN93569.1 - 3.5e-10 39.5 3.2 6.8e-05 22.6 0.0 3.2 3 0 0 3 3 3 2 ACT domain NAD_binding_3 PF03447.16 RLN93569.1 - 3.6e-06 27.6 0.4 3.1e-05 24.6 0.1 2.5 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Jiraiya PF15038.6 RLN93569.1 - 0.11 12.0 1.1 0.26 10.7 1.1 1.6 1 0 0 1 1 1 0 Jiraiya V-SNARE_C PF12352.8 RLN93569.1 - 0.23 11.8 0.8 0.59 10.5 0.1 2.1 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus PARP PF00644.20 RLN93570.1 - 6.6e-41 140.1 0.0 1.1e-40 139.3 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 RLN93570.1 - 1.4e-14 54.4 0.0 2.2e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 RLN93570.1 - 1.9e-09 37.4 0.0 4e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 WGR domain Securin PF04856.13 RLN93570.1 - 0.13 12.2 0.8 0.27 11.2 0.8 1.4 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor ORC6 PF05460.13 RLN93570.1 - 0.58 9.4 3.5 1.3 8.2 0.8 2.0 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Peptidase_M48 PF01435.18 RLN93571.1 - 9.7e-07 28.8 0.0 1.1e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 Myb_DNA-binding PF00249.31 RLN93572.1 - 7.7e-27 93.2 0.2 4.4e-13 49.2 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN93572.1 - 3.4e-18 65.7 0.0 2.4e-11 43.7 0.0 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN93572.1 - 9.8e-05 22.2 0.4 0.0045 16.9 0.0 2.8 2 1 1 3 3 3 1 Myb DNA-binding like DASH_Spc34 PF08657.10 RLN93572.1 - 0.0053 16.6 1.4 0.0099 15.7 1.4 1.4 1 0 0 1 1 1 1 DASH complex subunit Spc34 YabA PF06156.13 RLN93572.1 - 1 10.1 4.8 2.5 8.8 4.8 1.7 1 0 0 1 1 1 0 Initiation control protein YabA LPP20 PF02169.16 RLN93572.1 - 4.1 7.8 6.1 14 6.1 0.3 2.7 1 1 0 2 2 2 0 LPP20 lipoprotein TTL PF03133.15 RLN93573.1 - 1.2e-92 310.3 0.0 2.5e-92 309.1 0.0 1.5 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family Ion_trans PF00520.31 RLN93573.1 - 7.9e-21 74.4 15.7 1.2e-20 73.7 15.7 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RLN93573.1 - 1.7e-14 53.5 7.4 1.7e-14 53.5 7.4 2.6 2 1 0 2 2 2 1 Ion channel ATPgrasp_YheCD PF14398.6 RLN93573.1 - 3e-06 26.7 0.0 0.00091 18.5 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RLN93573.1 - 0.0038 16.5 0.0 0.16 11.2 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp PKD_channel PF08016.12 RLN93573.1 - 0.01 14.6 8.3 0.017 13.8 8.3 1.3 1 0 0 1 1 1 0 Polycystin cation channel Voltage_CLC PF00654.20 RLN93574.1 - 8.4e-34 117.4 12.7 1.1e-33 117.0 12.7 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel Abhydrolase_9_N PF15420.6 RLN93574.1 - 0.019 15.0 4.0 0.21 11.6 0.8 2.3 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus TPR_20 PF14561.6 RLN93575.1 - 0.21 11.9 8.0 0.75 10.2 0.7 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Hamartin PF04388.12 RLN93575.1 - 5.3 5.6 26.8 3.3 6.3 24.5 1.7 1 1 1 2 2 2 0 Hamartin protein CLASP_N PF12348.8 RLN93576.1 - 3.2e-07 30.2 0.3 0.00063 19.4 0.0 2.4 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 RLN93576.1 - 2e-06 27.6 0.0 0.76 10.2 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 RLN93576.1 - 6.3e-06 26.5 2.1 0.22 12.0 0.2 4.2 2 2 1 4 4 4 2 HEAT repeats FANCI_S2 PF14676.6 RLN93576.1 - 0.0011 19.3 1.7 0.039 14.3 0.8 2.7 2 0 0 2 2 2 1 FANCI solenoid 2 UBA2_C PF16195.5 RLN93576.1 - 0.011 16.4 2.9 0.011 16.4 2.9 2.6 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Adaptin_N PF01602.20 RLN93576.1 - 0.026 13.1 2.1 2.5 6.5 0.0 2.3 1 1 1 2 2 2 0 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 RLN93576.1 - 0.068 13.8 0.4 1.9 9.1 0.0 2.7 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 RLN93576.1 - 0.095 12.7 0.4 27 4.7 0.0 3.2 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 ADH_N PF08240.12 RLN93577.1 - 1.2e-27 96.0 1.4 1.2e-27 96.0 1.4 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN93577.1 - 8.3e-24 84.0 0.3 1.3e-23 83.4 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN93577.1 - 0.00026 22.0 0.2 0.00046 21.3 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_15 PF09445.10 RLN93577.1 - 0.009 15.6 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase adh_short PF00106.25 RLN93577.1 - 0.014 14.8 0.1 0.027 13.9 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 RLN93577.1 - 0.043 13.1 0.1 0.14 11.4 0.1 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Viral_Beta_CD PF04530.12 RLN93577.1 - 0.048 14.0 0.2 0.048 14.0 0.2 1.9 2 0 0 2 2 2 0 Viral Beta C/D like family PS_pyruv_trans PF04230.13 RLN93577.1 - 0.15 11.9 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase Homeobox_KN PF05920.11 RLN93580.1 - 4.8e-16 58.4 0.0 1.1e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 RLN93580.1 - 3.7e-08 33.1 0.1 8e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 Homeodomain DUF2040 PF09745.9 RLN93581.1 - 1.2e-33 115.8 13.0 1.2e-33 115.8 13.0 2.0 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) Ribosomal_L5e PF17144.4 RLN93582.1 - 2.2e-82 274.9 1.6 2.2e-82 274.9 1.6 2.1 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 RLN93582.1 - 2.7e-26 92.3 7.6 2.7e-26 92.3 7.6 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region NusG_add PF18298.1 RLN93582.1 - 0.0082 16.3 0.0 0.025 14.8 0.0 1.8 1 0 0 1 1 1 1 NusG additional domain Ribosomal_L14e PF01929.17 RLN93583.1 - 5.5e-29 100.5 6.1 5.5e-29 100.5 6.1 1.4 1 1 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 RLN93583.1 - 0.0011 18.9 0.0 0.0026 17.7 0.0 1.6 1 0 0 1 1 1 1 KOW motif Ank_4 PF13637.6 RLN93584.1 - 5.2e-10 39.6 0.9 1.3e-05 25.6 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN93584.1 - 2.6e-07 30.8 2.7 0.024 14.9 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN93584.1 - 1.9e-05 25.1 0.1 6e-05 23.6 0.1 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN93584.1 - 0.0043 17.4 0.2 27 5.8 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 RLN93584.1 - 0.0095 16.3 0.4 3.3 8.3 0.3 3.3 1 1 1 2 2 2 1 Ankyrin repeat SAM_3 PF18016.1 RLN93584.1 - 0.13 12.1 0.8 0.31 10.9 0.0 2.1 2 1 1 3 3 3 0 SAM domain (Sterile alpha motif) Ank_4 PF13637.6 RLN93585.1 - 5e-23 81.2 6.9 0.00015 22.2 0.1 7.2 5 1 3 8 8 8 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN93585.1 - 4.6e-22 78.4 3.3 2e-07 31.5 0.7 4.3 2 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN93585.1 - 1.5e-17 63.4 14.4 0.026 14.8 0.0 8.3 2 2 7 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN93585.1 - 2.9e-14 51.8 0.4 1.6 9.5 0.0 9.1 8 1 1 9 9 9 2 Ankyrin repeat Ank PF00023.30 RLN93585.1 - 0.0055 17.1 2.5 18 6.0 0.0 6.0 4 3 0 4 4 4 1 Ankyrin repeat SOR PF07682.11 RLN93585.1 - 0.029 13.3 0.2 0.053 12.4 0.2 1.4 1 0 0 1 1 1 0 Sulphur oxygenase reductase DUF1707 PF08044.11 RLN93585.1 - 0.086 12.9 0.6 53 4.0 0.0 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1707) DUF249 PF03158.13 RLN93585.1 - 0.21 11.3 0.3 13 5.4 0.0 3.6 2 2 2 4 4 4 0 Multigene family 530 protein DEP PF00610.21 RLN93585.1 - 1.8 8.6 3.9 38 4.5 0.1 4.1 4 1 1 5 5 5 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Chorion_S16 PF05836.12 RLN93585.1 - 2 8.7 5.1 3.5 7.9 0.2 3.2 1 1 3 4 4 4 0 Chorion protein S16 2-oxoacid_dh PF00198.23 RLN93586.1 - 1.4e-77 260.2 0.1 2e-77 259.7 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 RLN93586.1 - 1.2e-35 121.2 10.0 1.9e-19 69.3 3.5 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme HlyD_3 PF13437.6 RLN93586.1 - 0.00046 20.9 9.6 0.063 14.0 0.4 3.6 2 1 1 3 3 3 3 HlyD family secretion protein GCV_H PF01597.19 RLN93586.1 - 0.0024 17.7 4.3 0.39 10.6 0.7 2.6 2 0 0 2 2 2 2 Glycine cleavage H-protein Ribosomal_60s PF00428.19 RLN93586.1 - 0.048 14.3 1.3 0.048 14.3 1.3 3.8 2 1 1 3 3 3 0 60s Acidic ribosomal protein PYNP_C PF07831.13 RLN93586.1 - 0.32 10.7 1.6 18 5.0 0.1 2.8 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain Oxidored_FMN PF00724.20 RLN93587.1 - 7.2e-74 249.1 0.0 9.2e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PGM1_C PF18105.1 RLN93587.1 - 0.2 11.2 1.2 22 4.7 0.1 2.8 2 0 0 2 2 2 0 PGM1 C-terminal domain TFIIS_M PF07500.14 RLN93588.1 - 6.2e-19 68.5 0.0 1.4e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Methyltransf_16 PF10294.9 RLN93588.1 - 7.5e-05 22.5 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase DUF3725 PF12523.8 RLN93588.1 - 0.11 12.8 0.1 0.27 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) LRR_6 PF13516.6 RLN93589.1 - 1.2e-06 28.1 0.1 0.039 14.0 0.0 4.9 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 RLN93589.1 - 2.6e-06 27.7 0.0 0.15 12.5 0.0 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN93589.1 - 0.29 11.8 5.2 3.7 8.5 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat Lipase_3 PF01764.25 RLN93590.1 - 9.3e-31 106.6 0.0 1.9e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DSPc PF00782.20 RLN93590.1 - 6.7e-20 71.3 0.0 1e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.20 RLN93590.1 - 3.2e-05 24.1 0.1 9.4e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain Hydrolase_4 PF12146.8 RLN93590.1 - 0.0069 15.7 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Init_tRNA_PT PF04179.12 RLN93590.1 - 0.012 15.9 0.0 0.057 13.7 0.0 2.0 2 0 0 2 2 2 0 Rit1 DUSP-like domain Abhydrolase_5 PF12695.7 RLN93590.1 - 0.041 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Apyrase PF06079.11 RLN93590.1 - 0.059 12.6 0.0 0.097 11.8 0.0 1.2 1 0 0 1 1 1 0 Apyrase PGAP1 PF07819.13 RLN93590.1 - 0.09 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.8 RLN93590.1 - 0.12 12.0 0.1 0.81 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) COPIIcoated_ERV PF07970.12 RLN93591.1 - 6.6e-38 130.8 2.4 1.3e-37 129.8 2.4 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 RLN93591.1 - 4.2e-26 91.1 0.1 6.3e-26 90.5 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) MIP-T3 PF10243.9 RLN93594.1 - 7.9e-79 261.0 3.6 5.9e-39 132.5 0.0 3.2 3 0 0 3 3 3 2 Microtubule-binding protein MIP-T3 CH-like domain MIP-T3_C PF17749.1 RLN93594.1 - 2.2e-37 128.4 6.5 6e-37 127.0 6.5 1.8 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 C-terminal region Tektin PF03148.14 RLN93594.1 - 0.0092 14.8 4.8 0.021 13.6 4.8 1.5 1 0 0 1 1 1 1 Tektin family Fib_alpha PF08702.10 RLN93594.1 - 0.0092 16.2 2.7 0.022 15.0 2.7 1.6 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Tsc35 PF15079.6 RLN93594.1 - 0.053 13.1 1.8 0.12 11.9 1.8 1.5 1 0 0 1 1 1 0 Testis-specific protein 35 DUF1732 PF08340.11 RLN93594.1 - 0.071 13.1 0.9 0.26 11.3 0.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) SOGA PF11365.8 RLN93594.1 - 0.078 14.1 4.3 0.11 13.7 2.5 2.3 2 0 0 2 2 1 0 Protein SOGA DUF812 PF05667.11 RLN93594.1 - 0.14 11.0 7.6 0.26 10.1 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) UPF0242 PF06785.11 RLN93594.1 - 0.39 10.8 6.3 0.86 9.7 6.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Mod_r PF07200.13 RLN93594.1 - 0.63 10.1 7.8 0.63 10.1 5.2 2.4 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein AAA_23 PF13476.6 RLN93594.1 - 1.1 9.7 3.5 2.1 8.8 3.5 1.4 1 0 0 1 1 1 0 AAA domain SesA PF17107.5 RLN93594.1 - 1.4 9.2 5.4 1.5 9.0 0.1 2.9 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases MAP65_ASE1 PF03999.12 RLN93594.1 - 1.9 7.1 11.4 1.8 7.2 2.3 2.8 3 0 0 3 3 3 0 Microtubule associated protein (MAP65/ASE1 family) EMP24_GP25L PF01105.24 RLN93594.1 - 3.1 7.7 4.9 41 4.1 5.9 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF16 PF01519.16 RLN93594.1 - 9.4 6.8 7.5 43 4.7 6.6 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 Ist1 PF03398.14 RLN93595.1 - 6.2e-60 201.8 1.4 9.4e-60 201.3 1.4 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Oxidored_q6 PF01058.22 RLN93595.1 - 0.024 14.5 0.0 0.084 12.7 0.0 1.8 2 1 0 2 2 2 0 NADH ubiquinone oxidoreductase, 20 Kd subunit Sugar_tr PF00083.24 RLN93596.1 - 6.2e-07 28.6 1.2 7.3e-07 28.4 1.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN93596.1 - 0.0098 14.9 0.0 0.0098 14.9 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily LRR_6 PF13516.6 RLN93597.1 - 5e-13 48.0 9.7 0.1 12.7 0.0 8.7 9 0 0 9 9 9 5 Leucine Rich repeat LRR_8 PF13855.6 RLN93597.1 - 6.7e-05 22.6 11.1 0.00072 19.3 1.5 4.8 3 2 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 RLN93597.1 - 0.0022 18.3 11.2 0.28 11.6 0.0 5.1 3 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN93597.1 - 0.0044 17.4 5.4 1.3e+02 3.7 0.2 6.8 6 0 0 6 6 6 0 Leucine Rich Repeat SpoU_methylase PF00588.19 RLN93598.1 - 1.2e-23 83.9 0.1 6e-23 81.6 0.0 2.1 2 1 0 2 2 2 1 SpoU rRNA Methylase family sCache_3_2 PF17203.4 RLN93598.1 - 0.086 13.0 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 Single cache domain 3 SPARC_Ca_bdg PF10591.9 RLN93598.1 - 0.18 12.1 1.9 4.4 7.7 0.1 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Syja_N PF02383.18 RLN93599.1 - 1.2e-66 225.3 0.1 4.4e-56 190.5 0.0 2.1 1 1 1 2 2 2 2 SacI homology domain Lipase_GDSL PF00657.22 RLN93599.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Flavin_Reduct PF01613.18 RLN93600.1 - 0.056 13.5 0.0 0.11 12.6 0.0 1.5 2 0 0 2 2 2 0 Flavin reductase like domain MIP PF00230.20 RLN93601.1 - 3.1e-41 141.6 10.4 7.9e-39 133.7 10.4 2.4 1 1 0 1 1 1 1 Major intrinsic protein Tmemb_185A PF10269.9 RLN93603.1 - 1.2e-14 54.6 5.8 1.2e-14 54.6 5.8 2.7 2 1 0 2 2 2 1 Transmembrane Fragile-X-F protein DnaJ PF00226.31 RLN93603.1 - 4.8e-12 45.8 0.1 9.5e-12 44.9 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Zip PF02535.22 RLN93604.1 - 2.1e-50 171.8 9.2 2.4e-50 171.6 9.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2070 PF09843.9 RLN93604.1 - 0.19 10.0 8.6 0.32 9.2 8.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RRM_1 PF00076.22 RLN93605.1 - 5.1e-55 183.2 0.0 8e-20 70.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN93605.1 - 3.1e-08 33.6 0.0 0.17 12.0 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif OB_RNB PF08206.11 RLN93605.1 - 0.08 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain Nup35_RRM_2 PF14605.6 RLN93605.1 - 0.094 12.7 0.1 3.1 7.9 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif DUF1688 PF07958.11 RLN93606.1 - 6.9e-148 492.8 0.0 5.4e-146 486.6 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1688) MULE PF10551.9 RLN93607.1 - 8.3e-05 22.9 0.3 0.00023 21.5 0.3 1.7 1 0 0 1 1 1 1 MULE transposase domain Rif1_N PF12231.8 RLN93608.1 - 5.7e-23 81.5 7.9 9.1e-23 80.8 7.9 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal SPG48 PF14764.6 RLN93608.1 - 0.57 10.7 4.7 0.93 10.0 1.2 2.4 2 0 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking DUF883 PF05957.13 RLN93609.1 - 0.00089 19.8 6.9 0.0016 19.0 1.5 2.3 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 RLN93609.1 - 0.0075 16.2 2.4 0.011 15.6 2.4 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 RLN93609.1 - 0.085 12.9 0.5 0.48 10.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HisKA_3 PF07730.13 RLN93609.1 - 0.32 11.5 4.2 2.4 8.7 0.4 2.6 2 1 0 2 2 2 0 Histidine kinase HEAT PF02985.22 RLN93611.1 - 0.29 11.5 3.8 0.68 10.4 0.3 3.6 3 0 0 3 3 3 0 HEAT repeat Glyco_hydro81C PF17652.1 RLN93612.1 - 1.1e-118 396.5 2.5 1.1e-118 396.5 2.5 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 RLN93612.1 - 5.6e-55 186.8 1.3 8.9e-55 186.1 1.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain DUF3460 PF11943.8 RLN93614.1 - 0.02 15.1 0.6 0.02 15.1 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3460) p450 PF00067.22 RLN93615.1 - 1.4e-77 261.4 0.0 1.8e-77 261.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tub PF01167.18 RLN93616.1 - 3e-66 223.6 0.0 3.4e-66 223.4 0.0 1.0 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 RLN93616.1 - 0.023 14.3 0.1 0.053 13.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) p450 PF00067.22 RLN93617.1 - 7.8e-70 235.9 0.0 9.6e-70 235.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ATP19 PF11022.8 RLN93617.1 - 0.089 13.2 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 ATP synthase subunit K NA37 PF04245.13 RLN93617.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein p450 PF00067.22 RLN93618.1 - 1.3e-73 248.4 0.0 1.6e-73 248.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 RLN93619.1 - 1.8e-33 116.0 0.0 2e-33 115.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 RLN93620.1 - 2.8e-76 257.1 0.0 3.6e-76 256.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Steroid_dh PF02544.16 RLN93620.1 - 0.2 11.7 0.0 0.55 10.2 0.0 1.7 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase DehI PF10778.9 RLN93629.1 - 7.4 6.7 8.5 13 6.0 1.5 3.1 2 0 0 2 2 2 0 Halocarboxylic acid dehydrogenase DehI ubiquitin PF00240.23 RLN93630.1 - 0.015 15.1 0.1 0.044 13.5 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin family Peptidase_C39 PF03412.15 RLN93630.1 - 0.073 12.9 0.3 0.13 12.0 0.3 1.3 1 0 0 1 1 1 0 Peptidase C39 family Peptidase_M16 PF00675.20 RLN93630.1 - 0.22 11.5 1.8 0.44 10.5 1.8 1.4 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) GAS PF13851.6 RLN93631.1 - 0.018 14.4 10.0 0.026 13.9 10.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding YlqD PF11068.8 RLN93631.1 - 0.052 13.9 3.4 0.11 12.9 3.4 1.6 1 0 0 1 1 1 0 YlqD protein HTH_57 PF18679.1 RLN93631.1 - 0.053 13.8 3.3 0.34 11.3 3.3 2.1 1 1 0 1 1 1 0 ThcOx helix turn helix domain AAA_23 PF13476.6 RLN93631.1 - 0.23 11.9 1.6 0.31 11.5 1.6 1.4 1 0 0 1 1 1 0 AAA domain 5_3_exonuc PF01367.20 RLN93631.1 - 0.23 12.1 1.1 0.51 11.0 0.7 1.7 1 1 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Flagellin_N PF00669.20 RLN93631.1 - 0.5 10.5 5.1 3.3 7.8 0.2 2.4 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region APG6_N PF17675.1 RLN93631.1 - 0.85 10.2 15.9 2.9 8.4 15.9 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region Syntaxin-6_N PF09177.11 RLN93631.1 - 2.3 8.8 8.3 6.7 7.3 4.9 3.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal YabA PF06156.13 RLN93631.1 - 4.6 7.9 7.2 4.6 7.9 5.5 2.0 2 1 0 2 2 2 0 Initiation control protein YabA Lactonase PF10282.9 RLN93632.1 - 1.4e-58 198.8 0.0 1.6e-58 198.6 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SBP56 PF05694.11 RLN93632.1 - 0.072 11.9 0.0 0.17 10.7 0.0 1.6 1 1 1 2 2 2 0 56kDa selenium binding protein (SBP56) HAUS5 PF14817.6 RLN93634.1 - 2.2e-11 43.3 8.3 2.2e-11 43.3 8.3 2.0 2 0 0 2 2 2 2 HAUS augmin-like complex subunit 5 BT1 PF03092.16 RLN93635.1 - 3.4e-08 32.2 5.8 7.2e-07 27.8 0.3 2.5 2 0 0 2 2 2 2 BT1 family CcmD PF04995.14 RLN93635.1 - 0.62 10.2 0.0 0.62 10.2 0.0 3.7 4 0 0 4 4 4 0 Heme exporter protein D (CcmD) Lactonase PF10282.9 RLN93636.1 - 3.1e-83 279.9 0.4 3.8e-83 279.6 0.4 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 RLN93636.1 - 0.01 15.4 0.1 6.2 6.3 0.1 3.5 1 1 4 5 5 5 0 SMP-30/Gluconolactonase/LRE-like region WD40 PF00400.32 RLN93636.1 - 0.059 14.3 3.7 5 8.2 0.0 4.1 4 2 1 5 5 5 0 WD domain, G-beta repeat bZIP_Maf PF03131.17 RLN93637.1 - 0.021 15.3 2.7 0.05 14.1 2.7 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_1 PF00170.21 RLN93637.1 - 0.4 10.8 7.6 1 9.5 7.6 1.7 1 0 0 1 1 1 0 bZIP transcription factor RINT1_TIP1 PF04437.13 RLN93638.1 - 8.5e-37 127.2 0.0 3.5e-33 115.3 0.0 2.8 3 0 0 3 3 3 2 RINT-1 / TIP-1 family BRE1 PF08647.11 RLN93638.1 - 6.3 6.9 6.7 0.61 10.2 1.2 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase bZIP_1 PF00170.21 RLN93639.1 - 0.73 10.0 7.7 1.9 8.7 7.7 1.7 1 0 0 1 1 1 0 bZIP transcription factor Tubulin PF00091.25 RLN93640.1 - 3.4e-34 118.8 0.2 5.9e-34 118.0 0.2 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 RLN93640.1 - 2.3e-28 98.3 0.2 7.3e-28 96.7 0.2 1.9 1 0 0 1 1 1 1 FtsZ family, C-terminal domain OrfB_Zn_ribbon PF07282.11 RLN93641.1 - 8.3e-09 35.2 1.1 2.4e-08 33.8 1.1 1.7 1 1 0 1 1 1 1 Putative transposase DNA-binding domain MgtE_N PF03448.17 RLN93642.1 - 0.22 12.1 1.4 0.48 11.1 1.4 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain EnY2 PF10163.9 RLN93642.1 - 0.23 11.9 1.2 1.9 8.9 1.2 2.3 1 1 0 1 1 1 0 Transcription factor e(y)2 PUB PF09409.10 RLN93643.1 - 3.1e-16 59.1 0.1 8.4e-16 57.7 0.0 1.7 2 0 0 2 2 2 1 PUB domain Thioredoxin PF00085.20 RLN93643.1 - 1.7e-08 34.4 0.1 1.8e-07 31.1 0.1 2.6 1 1 0 1 1 1 1 Thioredoxin UBA PF00627.31 RLN93643.1 - 1e-07 31.7 0.1 2.4e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Macoilin PF09726.9 RLN93643.1 - 0.2 10.2 8.6 0.26 9.8 8.6 1.2 1 0 0 1 1 1 0 Macoilin family Thioredoxin_2 PF13098.6 RLN93643.1 - 0.45 11.0 2.3 2 8.9 0.0 2.8 3 1 1 4 4 4 0 Thioredoxin-like domain Fungal_TACC PF12709.7 RLN93643.1 - 3 8.3 12.9 1.9 9.0 3.8 3.5 3 1 1 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins Atg14 PF10186.9 RLN93643.1 - 4.9 6.1 7.1 8.5 5.4 7.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ABC_membrane PF00664.23 RLN93644.1 - 4.2e-47 161.1 8.8 1.8e-31 109.8 1.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN93644.1 - 1.2e-45 155.4 0.0 1.3e-26 93.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN93644.1 - 1.2e-11 45.0 0.0 0.013 15.3 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 RLN93644.1 - 4.6e-07 30.2 0.1 0.016 15.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 RLN93644.1 - 2e-06 27.8 0.0 0.021 14.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RLN93644.1 - 2.4e-06 27.6 0.0 0.047 13.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 RLN93644.1 - 2.4e-06 28.2 0.0 0.011 16.3 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 RLN93644.1 - 2.1e-05 24.2 0.0 0.32 10.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 RLN93644.1 - 5.6e-05 23.3 0.0 0.057 13.5 0.0 2.4 2 0 0 2 2 2 2 Dynamin family cobW PF02492.19 RLN93644.1 - 8.3e-05 22.2 0.1 0.32 10.5 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 RLN93644.1 - 8.5e-05 23.0 0.1 0.57 10.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 RLN93644.1 - 0.00036 19.7 0.3 0.24 10.4 0.0 2.6 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_33 PF13671.6 RLN93644.1 - 0.00098 19.3 0.0 0.88 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 RLN93644.1 - 0.0013 18.2 0.1 0.43 10.0 0.0 3.4 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 RLN93644.1 - 0.0015 18.3 0.1 0.13 12.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 RLN93644.1 - 0.0091 15.4 0.1 1.3 8.3 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_7 PF12775.7 RLN93644.1 - 0.013 15.1 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Guanylate_kin PF00625.21 RLN93644.1 - 0.014 15.1 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Guanylate kinase NACHT PF05729.12 RLN93644.1 - 0.015 15.2 0.1 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 RLN93644.1 - 0.021 15.4 0.0 9.4 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RLN93644.1 - 0.035 13.8 0.0 0.48 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 RLN93644.1 - 0.036 13.4 0.0 9.2 5.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 RLN93644.1 - 0.039 14.0 0.0 12 5.9 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 RLN93644.1 - 0.094 12.0 0.0 2 7.6 0.0 2.1 2 0 0 2 2 2 0 Septin dNK PF01712.19 RLN93644.1 - 0.097 12.5 0.0 13 5.5 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_25 PF13481.6 RLN93644.1 - 0.1 12.1 0.1 22 4.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 RLN93644.1 - 0.11 12.9 0.0 26 5.2 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 RLN93644.1 - 0.13 12.5 0.0 18 5.5 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 RLN93644.1 - 0.14 11.7 0.0 16 5.0 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 RLN93644.1 - 0.14 11.9 0.0 19 4.9 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 RLN93644.1 - 0.14 12.5 0.0 28 5.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 RLN93644.1 - 0.2 11.4 0.7 21 4.8 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein BTB PF00651.31 RLN93645.1 - 1.6e-31 108.8 0.1 9.3e-15 54.8 0.0 3.7 2 1 1 3 3 3 2 BTB/POZ domain RCC1_2 PF13540.6 RLN93645.1 - 9.5e-08 31.7 7.9 0.00056 19.6 2.1 2.6 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat BACK PF07707.15 RLN93645.1 - 0.032 14.3 0.4 0.1 12.7 0.4 1.8 1 0 0 1 1 1 0 BTB And C-terminal Kelch RCC1 PF00415.18 RLN93645.1 - 0.052 14.2 10.7 3.9 8.2 4.8 4.8 4 1 0 4 4 4 0 Regulator of chromosome condensation (RCC1) repeat ABC2_membrane PF01061.24 RLN93646.1 - 1.2e-36 126.2 20.3 2.1e-36 125.3 20.1 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RLN93646.1 - 5.6e-24 85.2 0.0 8.6e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN93646.1 - 1.2e-08 35.2 0.0 0.0013 18.7 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN93646.1 - 0.0003 21.2 0.3 0.00066 20.1 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 RLN93646.1 - 0.0024 17.8 0.1 0.0047 16.9 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 RLN93646.1 - 0.0043 16.6 0.1 0.034 13.7 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 RLN93646.1 - 0.0087 15.8 0.1 0.02 14.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN93646.1 - 0.02 15.4 0.0 0.033 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 RLN93646.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RLN93646.1 - 0.16 12.2 0.0 0.51 10.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 RLN93646.1 - 0.2 11.1 0.1 7 6.0 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 RLN93646.1 - 0.45 9.6 19.9 1.1 8.2 19.9 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein EF-hand_1 PF00036.32 RLN93647.1 - 3.7e-31 104.3 7.2 1.5e-06 27.3 0.0 6.7 7 0 0 7 7 7 6 EF hand EF-hand_7 PF13499.6 RLN93647.1 - 4.3e-29 100.8 7.3 6e-09 36.2 0.0 5.4 3 1 3 6 6 6 5 EF-hand domain pair EF-hand_6 PF13405.6 RLN93647.1 - 1.5e-26 90.0 6.6 4.6e-05 23.0 0.0 6.5 6 0 0 6 6 6 5 EF-hand domain EF-hand_5 PF13202.6 RLN93647.1 - 5.5e-24 82.6 5.1 1.3e-06 27.6 0.1 6.5 6 0 0 6 6 6 5 EF hand EF-hand_8 PF13833.6 RLN93647.1 - 2.3e-20 72.2 9.0 0.00057 19.7 0.3 6.3 6 0 0 6 6 6 5 EF-hand domain pair Caleosin PF05042.13 RLN93647.1 - 3.8e-05 23.7 0.1 3 7.8 0.0 4.2 2 2 2 4 4 4 2 Caleosin related protein EF-hand_9 PF14658.6 RLN93647.1 - 0.012 15.9 0.0 1 9.8 0.0 3.0 2 0 0 2 2 2 0 EF-hand domain UcrQ PF02939.16 RLN93647.1 - 0.023 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 UcrQ family FlpD PF02662.16 RLN93647.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit EF-hand_4 PF12763.7 RLN93647.1 - 0.17 11.9 0.7 2.5 8.1 0.1 3.0 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand TIG PF01833.24 RLN93649.1 - 0.1 12.7 0.0 0.37 10.9 0.0 1.9 1 1 0 1 1 1 0 IPT/TIG domain Antirestrict PF03230.13 RLN93649.1 - 0.14 12.2 0.0 0.47 10.5 0.0 1.8 1 1 1 2 2 2 0 Antirestriction protein TIG PF01833.24 RLN93650.1 - 1.5e-32 111.5 42.1 0.00027 21.0 0.0 18.7 21 1 0 21 21 21 11 IPT/TIG domain C2 PF00168.30 RLN93650.1 - 3.2e-08 33.8 0.0 5.7e-07 29.8 0.0 2.5 2 0 0 2 2 2 1 C2 domain Filamin PF00630.19 RLN93650.1 - 0.031 15.1 0.0 1 10.2 0.0 3.0 2 0 0 2 2 2 0 Filamin/ABP280 repeat UBA PF00627.31 RLN93651.1 - 8.6e-07 28.7 1.3 2.5e-06 27.3 0.2 2.5 2 0 0 2 2 2 1 UBA/TS-N domain LRR_4 PF12799.7 RLN93652.1 - 1e-11 44.9 3.8 7.4e-05 23.0 0.1 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN93652.1 - 1.7e-11 43.9 0.8 3.2e-10 39.8 0.7 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 RLN93652.1 - 5e-05 23.0 3.4 0.0046 16.7 2.0 2.5 2 0 0 2 2 2 2 Leucine rich repeat ParE_toxin PF05016.15 RLN93653.1 - 0.032 14.9 0.0 0.076 13.6 0.0 1.6 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE EF-hand_8 PF13833.6 RLN93653.1 - 0.079 12.8 0.0 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain pair Proteasome PF00227.26 RLN93654.1 - 1.7e-21 76.6 0.0 4.9e-21 75.1 0.0 1.6 1 1 0 1 1 1 1 Proteasome subunit HTH_45 PF14947.6 RLN93654.1 - 0.11 12.6 0.1 0.25 11.4 0.0 1.5 2 0 0 2 2 2 0 Winged helix-turn-helix DUF974 PF06159.13 RLN93655.1 - 1.4e-52 178.9 0.0 9.3e-52 176.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF974) Trs65 PF12735.7 RLN93655.1 - 1.5e-06 27.9 2.4 0.0046 16.4 0.1 2.3 1 1 1 2 2 2 2 TRAPP trafficking subunit Trs65 Transglut_C PF00927.22 RLN93655.1 - 0.017 15.2 0.2 0.1 12.7 0.1 2.1 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain Pkinase PF00069.25 RLN93656.1 - 7.3e-05 22.2 0.3 0.0002 20.8 0.3 1.7 1 0 0 1 1 1 1 Protein kinase domain DUF5039 PF16442.5 RLN93656.1 - 0.037 13.6 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) Pkinase PF00069.25 RLN93657.1 - 2.4e-31 109.1 0.0 3.9e-21 75.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN93657.1 - 1.3e-09 37.7 0.0 0.00073 18.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase PE_PPE_C PF12484.8 RLN93657.1 - 0.69 10.9 3.8 14 6.7 0.1 2.5 3 0 0 3 3 3 0 Polymorphic PE/PPE proteins C terminal Efg1 PF10153.9 RLN93658.1 - 8.2e-13 48.7 4.7 8.2e-13 48.7 4.7 3.5 3 1 1 4 4 4 1 rRNA-processing protein Efg1 TFIIA PF03153.13 RLN93658.1 - 0.068 13.2 6.2 0.088 12.8 6.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC117 PF15810.5 RLN93658.1 - 0.11 12.8 0.3 0.11 12.8 0.3 2.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 117 cNMP_binding PF00027.29 RLN93659.1 - 8.3e-40 134.8 0.1 3.5e-19 68.6 0.0 2.8 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain DUF5586 PF17824.1 RLN93659.1 - 0.033 13.3 0.0 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5586) Dpy-30 PF05186.13 RLN93659.1 - 0.1 12.3 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Dpy-30 motif FHA PF00498.26 RLN93660.1 - 6.4e-16 58.5 0.0 2.9e-09 37.1 0.0 3.8 4 0 0 4 4 4 2 FHA domain Yop-YscD_cpl PF16697.5 RLN93660.1 - 2.3e-15 56.7 0.0 6e-10 39.3 0.0 3.0 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain cNMP_binding PF00027.29 RLN93660.1 - 1e-12 48.0 1.5 5.4e-11 42.4 0.0 4.2 5 0 0 5 5 5 1 Cyclic nucleotide-binding domain RRM_1 PF00076.22 RLN93661.1 - 1.6e-05 24.6 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arf PF00025.21 RLN93662.1 - 5.8e-27 94.2 0.1 3.8e-16 59.0 0.2 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 RLN93662.1 - 0.002 17.6 0.0 0.0023 17.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RLN93662.1 - 0.018 14.2 0.0 0.018 14.2 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit 6PF2K PF01591.18 RLN93662.1 - 0.038 13.3 0.1 0.049 12.9 0.1 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase T2SSE PF00437.20 RLN93662.1 - 0.083 11.9 0.0 0.094 11.8 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 RLN93662.1 - 0.16 12.1 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 RLN93663.1 - 2.6e-26 92.1 0.1 6.6e-16 58.2 0.1 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 RLN93663.1 - 0.0029 17.1 0.1 0.0033 16.9 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RLN93663.1 - 0.02 14.1 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit 6PF2K PF01591.18 RLN93663.1 - 0.038 13.3 0.1 0.049 12.9 0.1 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ATP-synt_F PF01990.17 RLN93664.1 - 5.6e-18 65.0 3.2 3.7e-10 40.0 0.1 2.0 1 1 1 2 2 2 2 ATP synthase (F/14-kDa) subunit GARS_A PF01071.19 RLN93666.1 - 9.8e-81 270.2 0.0 1.6e-80 269.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.19 RLN93666.1 - 5.4e-44 150.1 0.1 9.9e-44 149.2 0.1 1.5 1 0 0 1 1 1 1 Formyl transferase GARS_N PF02844.15 RLN93666.1 - 5.1e-32 110.5 1.8 3.3e-31 107.9 0.1 3.3 4 0 0 4 4 4 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 RLN93666.1 - 6.5e-32 110.8 1.7 2.1e-31 109.2 0.0 2.8 4 0 0 4 4 4 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 RLN93666.1 - 2.4e-30 104.6 0.8 2.4e-30 104.6 0.8 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 RLN93666.1 - 2e-14 54.0 1.2 2e-14 54.0 1.2 3.4 4 0 0 4 4 3 1 AIR synthase related protein, N-terminal domain AICARFT_IMPCHas PF01808.18 RLN93666.1 - 5.4e-08 32.6 0.1 1.5e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 AICARFT/IMPCHase bienzyme ATP-grasp_3 PF02655.14 RLN93666.1 - 4e-06 27.0 0.0 3.7e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 RLN93666.1 - 0.00036 20.1 0.0 0.00064 19.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain E2R135 PF11570.8 RLN93666.1 - 0.016 15.5 0.0 0.036 14.4 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 CPSase_L_D2 PF02786.17 RLN93666.1 - 0.036 13.5 0.1 0.082 12.4 0.1 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain CoA_binding_2 PF13380.6 RLN93666.1 - 0.049 14.1 0.3 0.84 10.1 0.0 3.2 3 0 0 3 3 3 0 CoA binding domain MEDS PF14417.6 RLN93666.1 - 0.17 11.7 0.1 0.61 9.9 0.1 1.9 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain LAL_C2 PF18603.1 RLN93666.1 - 1.6 8.9 9.4 0.049 13.8 0.8 3.0 3 0 0 3 3 2 0 L-amino acid ligase C-terminal domain 2 CbiG_mid PF11761.8 RLN93667.1 - 5.2 7.3 6.3 1.2 9.3 1.6 2.5 2 0 0 2 2 2 0 Cobalamin biosynthesis central region Pkinase PF00069.25 RLN93669.1 - 4e-67 226.4 0.0 6.6e-67 225.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 RLN93669.1 - 5.1e-60 199.5 0.2 1.2e-18 67.0 0.0 4.1 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 RLN93669.1 - 6.1e-34 117.5 0.0 1.1e-33 116.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN93669.1 - 2.8e-05 23.6 0.0 5.3e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 RLN93669.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 RLN93669.1 - 0.027 14.4 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family 7TMR-HDED PF07697.11 RLN93669.1 - 0.11 12.5 0.9 1.9 8.6 0.0 2.9 3 1 0 3 3 3 0 7TM-HD extracellular DUF3636 PF12331.8 RLN93669.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) Fcf1 PF04900.12 RLN93670.1 - 4.4e-16 59.1 0.0 9.3e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 RLN93670.1 - 1.3e-05 25.5 0.7 2.1e-05 24.8 0.1 1.6 2 0 0 2 2 2 1 PIN like domain AA_permease_2 PF13520.6 RLN93671.1 - 8.9e-30 103.8 26.4 1.4e-29 103.2 26.4 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN93671.1 - 4.6e-12 45.3 22.2 8e-12 44.5 22.2 1.3 1 0 0 1 1 1 1 Amino acid permease TPR_14 PF13428.6 RLN93671.1 - 1.2e-08 35.0 3.6 0.68 10.9 0.1 6.2 3 1 3 6 6 6 3 Tetratricopeptide repeat Suf PF05843.14 RLN93671.1 - 2.4e-06 27.8 12.0 0.014 15.4 0.0 4.2 2 1 2 4 4 4 3 Suppressor of forked protein (Suf) HAT PF02184.16 RLN93671.1 - 6.9e-05 22.7 7.3 0.16 11.9 0.0 5.2 5 0 0 5 5 5 2 HAT (Half-A-TPR) repeat NRDE-2 PF08424.10 RLN93671.1 - 0.0019 17.4 12.8 1.6 7.8 1.4 5.0 3 2 2 5 5 5 2 NRDE-2, necessary for RNA interference TPR_12 PF13424.6 RLN93671.1 - 0.0052 17.0 0.8 0.97 9.8 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 RLN93671.1 - 0.007 16.3 11.8 0.2 11.6 3.5 4.9 3 2 1 4 4 4 1 Mad3/BUB1 homology region 1 U3_assoc_6 PF08640.11 RLN93671.1 - 0.16 12.1 0.2 4.4 7.4 0.0 3.2 4 0 0 4 4 4 0 U3 small nucleolar RNA-associated protein 6 BOFC_N PF08977.10 RLN93671.1 - 8 6.5 5.7 1.5 8.8 0.1 2.8 4 0 0 4 4 4 0 Bypass of Forespore C, N terminal Exo_endo_phos PF03372.23 RLN93672.1 - 6.6e-17 61.8 0.0 1.6e-16 60.5 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Hema_esterase PF03996.15 RLN93672.1 - 0.038 13.8 0.1 0.057 13.2 0.1 1.2 1 0 0 1 1 1 0 Hemagglutinin esterase DUF2183 PF09949.9 RLN93673.1 - 8.6e-08 32.4 0.0 1.9e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Gemin7 PF11095.8 RLN93673.1 - 0.00037 20.3 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) HTH_psq PF05225.16 RLN93674.1 - 2e-06 27.4 0.4 0.0086 15.8 0.2 2.6 2 0 0 2 2 2 2 helix-turn-helix, Psq domain HTH_23 PF13384.6 RLN93674.1 - 0.0094 15.7 1.4 2 8.3 0.1 2.9 2 0 0 2 2 2 2 Homeodomain-like domain UPF0175 PF03683.13 RLN93674.1 - 0.16 11.7 0.2 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0175) HTH_28 PF13518.6 RLN93674.1 - 0.53 10.5 3.2 5.6 7.2 0.1 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain PRIMA1 PF16101.5 RLN93674.1 - 1.6 8.8 11.9 0.32 11.0 4.4 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 HTH_30 PF13556.6 RLN93674.1 - 2.6 7.9 6.5 0.4 10.5 0.8 2.4 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain CAP_N PF01213.19 RLN93674.1 - 6.3 6.2 13.0 0.82 9.1 3.9 2.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Copine PF07002.16 RLN93675.1 - 1.9e-27 96.2 0.0 2.3e-19 69.7 0.0 3.3 2 1 1 3 3 3 3 Copine C2 PF00168.30 RLN93675.1 - 5.2e-26 90.9 0.0 5.4e-14 52.3 0.0 2.3 2 0 0 2 2 2 2 C2 domain Abhydrolase_3 PF07859.13 RLN93676.1 - 7e-31 107.7 0.0 1.3e-30 106.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN93676.1 - 1.6e-09 37.1 0.0 2.3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase PNK3P PF08645.11 RLN93676.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase MgtE PF01769.16 RLN93676.1 - 1.2 9.5 8.8 2 8.8 8.8 1.3 1 0 0 1 1 1 0 Divalent cation transporter Ribosomal_S10 PF00338.22 RLN93677.1 - 9.2e-29 99.6 0.1 1.2e-28 99.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PTEN_C2 PF10409.9 RLN93680.1 - 0.051 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein GIT_SHD PF08518.11 RLN93681.1 - 0.1 12.3 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT DUF445 PF04286.12 RLN93681.1 - 0.11 12.3 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF4200 PF13863.6 RLN93683.1 - 6.1e-34 117.0 25.8 6.1e-34 117.0 25.8 4.7 2 2 1 4 4 4 1 Domain of unknown function (DUF4200) YvrJ PF12841.7 RLN93683.1 - 0.054 13.0 0.1 0.19 11.3 0.1 2.0 1 0 0 1 1 1 0 YvrJ protein family Bacillus_HBL PF05791.11 RLN93683.1 - 0.34 10.7 22.8 0.53 10.1 4.6 3.3 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) NPV_P10 PF05531.12 RLN93683.1 - 4.8 7.7 11.0 0.42 11.1 2.2 3.2 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein FYVE PF01363.21 RLN93684.1 - 4.6e-12 45.9 12.3 4.6e-12 45.9 12.3 1.7 2 0 0 2 2 2 1 FYVE zinc finger GAF PF01590.26 RLN93684.1 - 8.6e-07 29.7 0.1 2.8e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 GAF domain FYVE_2 PF02318.16 RLN93684.1 - 0.0016 18.6 4.4 0.0016 18.6 4.4 2.1 3 0 0 3 3 3 1 FYVE-type zinc finger PEGSRP PF07623.11 RLN93684.1 - 0.055 13.3 0.1 0.18 11.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) RRM_1 PF00076.22 RLN93685.1 - 8.8e-15 54.3 0.0 1.8e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN93685.1 - 0.00026 21.1 0.0 0.00068 19.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif HET-S PF17108.5 RLN93685.1 - 0.58 9.9 2.9 14 5.6 0.2 2.4 2 0 0 2 2 2 0 N-terminal small S protein of HET, non-prionic WD40 PF00400.32 RLN93686.1 - 2.1e-28 98.0 8.4 2.7e-07 31.2 0.1 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat Bromodomain PF00439.25 RLN93686.1 - 6e-28 96.7 0.2 2.8e-16 59.3 0.4 2.6 2 0 0 2 2 2 2 Bromodomain zf-HC5HC2H PF13771.6 RLN93686.1 - 4e-08 33.4 6.6 4e-08 33.4 6.6 2.3 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 RLN93686.1 - 2.1e-05 24.7 4.1 2.1e-05 24.7 4.1 1.9 2 0 0 2 2 2 1 PHD-zinc-finger like domain TFIIA PF03153.13 RLN93686.1 - 0.00018 21.7 0.4 0.00018 21.7 0.4 5.0 4 1 0 4 4 4 1 Transcription factor IIA, alpha/beta subunit Auxin_resp PF06507.13 RLN93686.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Auxin response factor Nup160 PF11715.8 RLN93686.1 - 1.4 7.5 8.1 1.7 7.2 0.1 2.9 3 0 0 3 3 3 0 Nucleoporin Nup120/160 TAF6_C PF07571.13 RLN93687.1 - 0.022 15.0 0.0 0.027 14.8 0.0 1.2 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain CO_dh PF02552.16 RLN93687.1 - 0.22 11.3 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit adh_short PF00106.25 RLN93688.1 - 9.7e-17 61.1 0.1 1.3e-16 60.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN93688.1 - 6.8e-09 35.6 0.1 9.4e-09 35.2 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF5412 PF17428.2 RLN93689.1 - 0.26 11.2 0.0 0.41 10.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5412) ETS_PEA3_N PF04621.13 RLN93689.1 - 0.62 9.9 6.4 0.85 9.4 5.4 1.7 1 1 1 2 2 2 0 PEA3 subfamily ETS-domain transcription factor N terminal domain FYVE PF01363.21 RLN93690.1 - 1.3e-25 89.3 33.6 2.1e-15 56.6 9.9 3.7 4 0 0 4 4 4 2 FYVE zinc finger DnaJ PF00226.31 RLN93690.1 - 5.7e-10 39.2 0.3 3.7e-09 36.6 0.2 2.6 2 0 0 2 2 2 1 DnaJ domain PX PF00787.24 RLN93690.1 - 2.7e-05 24.1 0.0 8.3e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 PX domain zinc_ribbon_2 PF13240.6 RLN93690.1 - 9e-05 22.1 0.8 9e-05 22.1 0.8 2.9 3 0 0 3 3 3 1 zinc-ribbon domain FYVE_2 PF02318.16 RLN93690.1 - 0.00077 19.7 3.6 0.00077 19.7 3.6 6.9 7 1 2 9 9 9 2 FYVE-type zinc finger ERM PF00769.19 RLN93690.1 - 0.0024 17.7 21.7 0.0024 17.7 21.7 5.2 4 1 2 6 6 6 2 Ezrin/radixin/moesin family DZR PF12773.7 RLN93690.1 - 0.0035 17.3 0.4 0.0035 17.3 0.4 5.1 3 2 1 4 4 4 1 Double zinc ribbon bZIP_1 PF00170.21 RLN93690.1 - 0.0053 16.8 3.4 0.0053 16.8 3.4 5.8 5 1 0 5 5 5 1 bZIP transcription factor zinc_ribbon_15 PF17032.5 RLN93690.1 - 0.068 13.9 0.4 0.068 13.9 0.4 4.2 3 1 1 4 4 4 0 zinc-ribbon family Kelch_4 PF13418.6 RLN93691.1 - 1.8e-25 88.6 8.2 1.5e-05 24.9 0.1 7.1 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN93691.1 - 1.8e-22 78.8 15.1 6.4e-05 22.8 0.0 6.8 6 1 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 RLN93691.1 - 1.1e-21 76.6 20.6 3e-07 30.6 0.1 7.4 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.25 RLN93691.1 - 5.1e-21 74.0 12.2 1.2e-06 28.0 0.0 6.4 6 1 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 RLN93691.1 - 1.9e-20 72.3 19.3 1.2e-06 28.5 0.0 6.7 5 3 1 6 6 6 3 Kelch motif zf-RING_2 PF13639.6 RLN93691.1 - 1.4e-10 41.4 1.4 2.5e-10 40.5 1.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RLN93691.1 - 5.9e-10 39.3 1.3 1.1e-09 38.5 1.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain Kelch_2 PF07646.15 RLN93691.1 - 8.6e-10 38.2 16.3 2.1e-05 24.3 0.1 6.0 6 3 0 6 6 5 3 Kelch motif zf-C3HC4_2 PF13923.6 RLN93691.1 - 4e-07 29.8 1.0 6.7e-07 29.0 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN93691.1 - 1.3e-06 28.0 0.5 2.4e-06 27.2 0.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 RLN93691.1 - 1.7e-06 27.7 0.9 3e-06 27.0 0.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN93691.1 - 1.3e-05 25.0 0.5 2.3e-05 24.2 0.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN93691.1 - 1.8e-05 24.6 0.5 2.9e-05 23.9 0.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 RLN93691.1 - 3.3e-05 23.8 0.2 6.9e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RLN93691.1 - 0.00064 19.5 0.4 0.001 18.9 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 RLN93691.1 - 0.00089 18.8 1.5 0.0017 17.9 1.5 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 RLN93691.1 - 0.0039 17.2 0.1 0.0078 16.2 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3H2C3 PF17122.5 RLN93691.1 - 0.058 13.4 1.8 0.12 12.4 1.8 1.5 1 0 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 RLN93691.1 - 0.096 12.9 3.3 0.49 10.6 3.3 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 RLN93691.1 - 0.21 11.7 2.6 0.43 10.8 2.6 1.4 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 RLN93691.1 - 0.33 10.8 1.4 0.66 9.8 1.1 1.6 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 RLN93691.1 - 0.35 11.2 2.0 0.63 10.4 2.0 1.3 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 RLN93691.1 - 0.39 10.9 1.2 0.68 10.1 1.2 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ATP-synt_10 PF05176.14 RLN93692.1 - 3e-23 82.4 0.0 4.1e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein E1_dh PF00676.20 RLN93692.1 - 0.027 13.4 0.4 0.042 12.8 0.4 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component EB_dh PF09459.10 RLN93693.1 - 0.06 13.3 0.2 0.1 12.6 0.2 1.3 1 0 0 1 1 1 0 Ethylbenzene dehydrogenase Plasmodium_Vir PF05795.11 RLN93694.1 - 0.42 10.0 4.7 0.81 9.0 4.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SDA1 PF05285.12 RLN93694.1 - 8.1 5.8 20.4 14 5.0 20.4 1.3 1 0 0 1 1 1 0 SDA1 FdtA PF05523.11 RLN93695.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 WxcM-like, C-terminal ABC2_membrane PF01061.24 RLN93696.1 - 3.8e-32 111.4 33.7 3.8e-32 111.4 33.7 1.7 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN93696.1 - 0.0071 16.2 0.0 0.0071 16.2 0.0 2.7 3 0 0 3 3 3 1 CDR ABC transporter DUF3810 PF12725.7 RLN93696.1 - 1 8.7 4.3 2 7.7 4.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) ACOX PF01756.19 RLN93698.1 - 2.5e-50 170.5 0.0 5.4e-50 169.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 RLN93698.1 - 2.4e-28 99.2 0.1 4.8e-28 98.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 RLN93698.1 - 2.7e-13 49.9 0.0 6.2e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 RLN93698.1 - 0.014 15.6 0.7 0.031 14.5 0.1 1.9 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Arrestin_C PF02752.22 RLN93699.1 - 1.7e-16 60.9 0.0 2.3e-11 44.3 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 RLN93699.1 - 2.4e-11 43.9 0.1 9.5e-09 35.5 0.1 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 RLN93699.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like SLC12 PF03522.15 RLN93700.1 - 0.56 9.2 4.9 0.66 8.9 4.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 RLN93700.1 - 1.3 6.1 6.1 1.5 5.9 6.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOBP PF15279.6 RLN93700.1 - 1.5 9.3 12.1 1.9 9.1 12.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SRP-alpha_N PF04086.13 RLN93700.1 - 1.8 8.4 17.6 2.4 8.0 17.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SOG2 PF10428.9 RLN93700.1 - 2.2 7.4 9.9 2.7 7.1 9.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 RLN93700.1 - 2.4 6.8 6.2 2.4 6.7 6.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Menin PF05053.13 RLN93700.1 - 3.5 5.9 9.7 4.3 5.6 9.7 1.1 1 0 0 1 1 1 0 Menin BSP_II PF05432.11 RLN93700.1 - 3.6 7.2 26.0 5 6.7 26.0 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF4551 PF15087.6 RLN93700.1 - 6.5 5.5 8.8 7.5 5.3 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CDC45 PF02724.14 RLN93700.1 - 9.5 4.4 9.7 11 4.1 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 RLN93700.1 - 9.9 4.1 11.2 12 3.9 11.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Osmo_CC PF08946.10 RLN93701.1 - 0.02 15.1 0.2 0.072 13.3 0.2 2.0 1 0 0 1 1 1 0 Osmosensory transporter coiled coil PI_PP_I PF18363.1 RLN93701.1 - 0.023 14.9 0.1 19 5.5 0.0 3.2 3 0 0 3 3 3 0 Phosphoinositide phosphatase insertion domain APP_E2 PF12925.7 RLN93701.1 - 0.16 11.7 7.7 2.1 8.0 0.5 2.9 2 1 0 2 2 2 0 E2 domain of amyloid precursor protein Goodbye PF17109.5 RLN93701.1 - 7.8 7.0 5.9 16 6.0 0.1 3.3 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain AI-2E_transport PF01594.16 RLN93702.1 - 0.00086 18.6 15.0 0.00086 18.6 15.0 4.2 3 1 1 4 4 4 2 AI-2E family transporter SAYSvFN PF10260.9 RLN93702.1 - 1.1 9.3 5.9 3.6 7.6 2.2 2.9 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) RRN3 PF05327.11 RLN93702.1 - 3.1 6.2 20.0 6.6 5.2 20.0 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ank_5 PF13857.6 RLN93703.1 - 2e-34 117.2 4.8 3.7e-10 39.9 0.5 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN93703.1 - 6.3e-31 106.8 1.0 5.8e-12 46.0 0.3 3.3 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN93703.1 - 7.1e-30 103.0 0.5 1e-10 41.9 0.1 4.2 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN93703.1 - 7.1e-26 87.4 3.2 0.00026 21.2 0.0 5.7 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 RLN93703.1 - 1.2e-21 76.2 10.6 1.7e-05 25.0 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat N_Asn_amidohyd PF14736.6 RLN93704.1 - 2.5e-33 115.4 0.0 4.5e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase EPV_E5 PF08135.11 RLN93705.1 - 0.014 15.8 1.2 0.02 15.3 1.2 1.3 1 0 0 1 1 1 0 Major transforming protein E5 family T_cell_tran_alt PF15128.6 RLN93705.1 - 0.038 13.8 0.1 0.054 13.3 0.1 1.4 1 1 0 1 1 1 0 T-cell leukemia translocation-altered PTA_PTB PF01515.19 RLN93706.1 - 1.7e-82 277.3 0.0 3.2e-82 276.4 0.0 1.4 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase AAA_26 PF13500.6 RLN93706.1 - 1.2e-19 70.9 0.0 1.9e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DRTGG PF07085.12 RLN93706.1 - 1.4e-16 60.1 0.0 3.7e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 DRTGG domain CbiA PF01656.23 RLN93706.1 - 0.00063 19.8 0.1 0.0052 16.9 0.0 2.5 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain HTH_Tnp_Tc3_2 PF01498.18 RLN93708.1 - 0.0069 16.6 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Transposase UMPH-1 PF05822.12 RLN93708.1 - 0.026 14.0 0.3 0.038 13.5 0.3 1.3 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) DUF3995 PF13160.6 RLN93709.1 - 5.9 7.3 8.1 5 7.5 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) DUF733 PF05306.11 RLN93710.1 - 0.06 13.6 0.2 0.06 13.6 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF733) TFIIA PF03153.13 RLN93710.1 - 0.22 11.5 8.4 0.3 11.0 8.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FYVE PF01363.21 RLN93711.1 - 2e-06 27.8 4.2 3.4e-06 27.1 4.2 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN93711.1 - 0.0071 16.5 2.9 0.014 15.6 2.9 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger BNIP2 PF12496.8 RLN93711.1 - 0.16 12.4 6.3 0.25 11.8 6.3 1.3 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 2OG-FeII_Oxy_2 PF13532.6 RLN93715.1 - 7.5e-24 85.0 0.1 1.1e-23 84.5 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 RLN93715.1 - 0.0045 17.4 0.0 0.015 15.8 0.0 1.9 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily HECT PF00632.25 RLN93716.1 - 3.4e-75 253.4 0.0 4.3e-75 253.1 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Peptidase_C1 PF00112.23 RLN93717.1 - 8.5e-53 179.7 6.3 8.5e-53 179.7 6.3 2.3 2 0 0 2 2 2 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RLN93717.1 - 0.0023 16.8 2.4 0.061 12.1 0.3 2.1 2 0 0 2 2 2 2 Peptidase C1-like family DUF4505 PF14956.6 RLN93718.1 - 2.9e-21 76.0 0.0 4.7e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) Cyt-b5 PF00173.28 RLN93718.1 - 5.6e-12 45.6 0.0 1.2e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain F-box-like PF12937.7 RLN93718.1 - 0.00082 19.2 3.1 0.00089 19.1 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RLN93718.1 - 0.0024 17.7 0.1 0.0057 16.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain DUF4506 PF14958.6 RLN93719.1 - 1.5e-08 34.2 0.0 7.8e-08 31.9 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4506) Rab5-bind PF09311.11 RLN93719.1 - 0.0054 16.2 1.8 0.0092 15.4 1.8 1.3 1 0 0 1 1 1 1 Rabaptin-like protein PilJ PF13675.6 RLN93719.1 - 0.043 13.8 3.9 1.3 9.0 2.6 2.4 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Exonuc_VII_L PF02601.15 RLN93719.1 - 0.047 13.3 1.9 0.064 12.8 1.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ABC_tran_CTD PF16326.5 RLN93719.1 - 2.4 8.5 5.2 6.1 7.2 4.3 2.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF1178 PF06676.11 RLN93720.1 - 0.0054 17.1 1.2 0.012 16.0 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1178) Thioredoxin_3 PF13192.6 RLN93720.1 - 0.3 11.2 0.6 6.3 6.9 0.3 2.7 2 0 0 2 2 2 0 Thioredoxin domain TPR_12 PF13424.6 RLN93721.1 - 2.1e-17 63.1 3.6 1.5e-09 38.0 0.2 3.0 2 1 2 4 4 4 2 Tetratricopeptide repeat SH2 PF00017.24 RLN93721.1 - 8.8e-12 45.0 0.1 1.7e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 SH2 domain TPR_1 PF00515.28 RLN93721.1 - 8.3e-09 34.9 0.8 8.1e-06 25.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN93721.1 - 2.4e-08 33.4 0.4 4e-05 23.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN93721.1 - 6.9e-06 25.8 0.4 0.00074 19.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN93721.1 - 1.1e-05 25.1 5.2 0.00018 21.3 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN93721.1 - 2e-05 24.4 0.0 0.00032 20.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN93721.1 - 0.077 13.7 1.1 0.73 10.5 0.2 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat Sec63 PF02889.16 RLN93722.1 - 5.8e-39 133.8 0.0 8.8e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 RLN93722.1 - 1.1e-19 70.3 0.0 2.6e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain CDC45 PF02724.14 RLN93723.1 - 0.33 9.2 6.4 0.4 8.9 6.4 1.0 1 0 0 1 1 1 0 CDC45-like protein TTL PF03133.15 RLN93724.1 - 3.2e-64 216.9 0.0 5.2e-64 216.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SPT6_acidic PF14632.6 RLN93724.1 - 0.12 12.9 1.1 0.3 11.7 1.1 1.6 1 0 0 1 1 1 0 Acidic N-terminal SPT6 UFD1 PF03152.14 RLN93725.1 - 4.1e-18 65.5 0.0 5.3e-17 61.8 0.0 2.1 1 1 1 2 2 2 1 Ubiquitin fusion degradation protein UFD1 Hist_deacetyl PF00850.19 RLN93725.1 - 2.1e-13 50.4 0.0 7.5e-13 48.6 0.0 1.8 2 0 0 2 2 2 1 Histone deacetylase domain CAP-ZIP_m PF15255.6 RLN93726.1 - 0.11 12.8 2.3 0.33 11.2 2.3 1.8 1 1 0 1 1 1 0 WASH complex subunit CAP-Z interacting, central region CK2S PF15011.6 RLN93729.1 - 1.4e-05 25.0 0.4 4.1e-05 23.5 0.4 1.7 1 1 0 1 1 1 1 Casein Kinase 2 substrate ICMT PF04140.14 RLN93730.1 - 1.1e-28 99.5 0.7 1.8e-28 98.8 0.2 1.6 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 RLN93730.1 - 5.4e-11 42.8 0.4 5.4e-11 42.8 0.4 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 RLN93730.1 - 0.0092 15.5 0.4 0.017 14.7 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF2627 PF11118.8 RLN93730.1 - 0.38 11.4 5.2 12 6.6 0.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2627) Y_phosphatase2 PF03162.13 RLN93731.1 - 2.9e-34 118.0 0.0 3.7e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 RLN93731.1 - 8.4e-06 25.5 0.0 9.2e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 RLN93731.1 - 0.0035 17.5 0.0 0.0053 16.9 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 RLN93731.1 - 0.0098 15.9 0.1 0.017 15.1 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 RLN93731.1 - 0.022 14.5 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Carn_acyltransf PF00755.20 RLN93732.1 - 1e-182 608.9 0.0 1.2e-182 608.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DDE_Tnp_1_7 PF13843.6 RLN93735.1 - 3.5e-09 36.4 0.2 1.3e-08 34.6 0.1 1.8 1 1 1 2 2 2 1 Transposase IS4 Cellulase PF00150.18 RLN93736.1 - 7.5e-21 74.8 1.6 9.8e-21 74.4 1.6 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pex14_N PF04695.13 RLN93736.1 - 0.023 15.4 0.3 0.049 14.3 0.3 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cellulase PF00150.18 RLN93737.1 - 9.4e-22 77.7 0.7 1.2e-21 77.4 0.7 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Aminotran_5 PF00266.19 RLN93738.1 - 3.4e-43 148.0 0.0 5.1e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V ATP_bind_3 PF01171.20 RLN93738.1 - 1.9e-15 57.1 0.0 4e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 PP-loop family Aminotran_5 PF00266.19 RLN93739.1 - 0.0017 17.4 0.0 0.0027 16.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V EMP70 PF02990.16 RLN93740.1 - 9.8e-75 252.2 0.0 1.3e-74 251.8 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Cellulase PF00150.18 RLN93740.1 - 1.3e-24 87.1 0.4 1.7e-24 86.7 0.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GYD PF08734.11 RLN93740.1 - 0.12 12.3 0.2 0.51 10.3 0.0 2.1 2 0 0 2 2 2 0 GYD domain Cellulase PF00150.18 RLN93741.1 - 1.6e-21 77.0 0.9 1.9e-21 76.7 0.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) LysM PF01476.20 RLN93743.1 - 0.028 14.5 0.0 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 LysM domain Histone PF00125.24 RLN93744.1 - 5.6e-40 136.7 0.8 6.7e-40 136.5 0.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 RLN93744.1 - 0.00031 21.1 0.0 0.00041 20.7 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 RLN93744.1 - 0.00036 20.6 0.0 0.00044 20.3 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 RLN93744.1 - 0.01 16.1 0.0 0.014 15.7 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 RLN93744.1 - 0.016 15.3 0.0 0.018 15.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Pex2_Pex12 PF04757.14 RLN93745.1 - 5.9e-19 68.6 0.0 7.7e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region CENP-T_C PF15511.6 RLN93746.1 - 1.7e-08 34.5 0.1 2.1e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 RLN93746.1 - 0.00019 21.7 0.1 0.00025 21.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 RLN93746.1 - 0.0003 20.9 0.1 0.00042 20.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 RLN93746.1 - 0.004 17.4 0.0 0.0067 16.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 RLN93746.1 - 0.0046 17.3 0.2 0.0052 17.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 RLN93746.1 - 0.027 14.5 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 RLN93746.1 - 0.053 13.5 0.1 0.079 13.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 RLN93746.1 - 0.18 11.6 0.1 0.22 11.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) ABC_tran PF00005.27 RLN93747.1 - 5.5e-22 78.7 0.0 9.1e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN93747.1 - 6.8e-09 35.9 0.4 0.0016 18.3 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN93747.1 - 1.7e-05 25.3 0.1 3.2e-05 24.4 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 RLN93747.1 - 2.3e-05 24.4 0.1 4e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 RLN93747.1 - 0.00027 21.2 0.3 0.0041 17.4 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 RLN93747.1 - 0.0004 20.1 0.1 0.00095 18.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 RLN93747.1 - 0.00041 19.8 0.2 0.18 11.2 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 RLN93747.1 - 0.00058 19.6 0.0 0.00082 19.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 RLN93747.1 - 0.0028 18.2 0.0 0.006 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_35 PF14516.6 RLN93747.1 - 0.0036 16.2 0.0 0.0075 15.1 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain AAA_25 PF13481.6 RLN93747.1 - 0.0044 16.6 0.0 0.11 12.1 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 RLN93747.1 - 0.0092 16.3 0.0 0.016 15.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 RLN93747.1 - 0.0097 15.2 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 RLN93747.1 - 0.045 13.7 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 RLN93747.1 - 0.049 13.9 0.0 0.076 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 RLN93747.1 - 0.059 13.8 0.2 0.27 11.6 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 RLN93747.1 - 0.098 12.6 0.0 0.1 12.5 0.0 1.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Histidinol_dh PF00815.20 RLN93748.1 - 5.8e-102 341.8 2.8 2.5e-96 323.2 3.0 2.2 1 1 1 2 2 2 2 Histidinol dehydrogenase Cation_ATPase_N PF00690.26 RLN93748.1 - 0.024 14.3 0.6 2.3 8.0 0.1 2.6 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus Pkinase PF00069.25 RLN93749.1 - 2.5e-47 161.5 0.0 3.2e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN93749.1 - 2.8e-16 59.6 0.0 4.1e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN93749.1 - 0.0017 17.7 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN93749.1 - 0.0075 16.2 0.1 0.022 14.7 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN93749.1 - 0.023 14.0 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN93749.1 - 0.16 10.7 0.1 0.51 9.0 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase OCC1 PF15506.6 RLN93749.1 - 2.1 8.5 8.3 5 7.3 2.9 2.5 2 0 0 2 2 2 0 OCC1 family Pkinase PF00069.25 RLN93750.1 - 1.3e-44 152.6 0.0 1.6e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN93750.1 - 3.5e-31 108.4 0.0 4.3e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN93750.1 - 0.00029 20.3 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN93750.1 - 0.0027 17.7 0.0 1.8 8.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN93750.1 - 0.0044 15.8 0.0 0.0058 15.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 RLN93750.1 - 0.051 12.9 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Actin PF00022.19 RLN93751.1 - 7e-69 232.4 0.0 5.2e-63 213.1 0.0 3.0 2 1 0 2 2 2 2 Actin TLE_N PF03920.15 RLN93752.1 - 0.096 12.8 2.9 0.15 12.1 2.9 1.2 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain Arm PF00514.23 RLN93753.1 - 5e-82 267.7 17.1 8.6e-12 44.7 0.0 9.0 9 1 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN93753.1 - 3.7e-17 62.5 0.4 7.1e-06 26.3 0.2 6.0 3 2 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 RLN93753.1 - 1.5e-15 57.3 12.8 7.8e-05 23.1 0.0 7.0 7 2 2 9 9 7 4 HEAT-like repeat HEAT PF02985.22 RLN93753.1 - 4.2e-13 48.3 8.8 0.17 12.3 0.0 7.8 9 0 0 9 9 8 4 HEAT repeat IBB PF01749.20 RLN93753.1 - 1.8e-09 37.9 8.9 7.1e-09 36.0 8.9 2.0 1 1 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 RLN93753.1 - 5.7e-07 29.0 2.2 3.9e-06 26.3 0.5 2.4 2 0 0 2 2 2 1 Atypical Arm repeat RasGEF_N_2 PF14663.6 RLN93753.1 - 0.0032 17.9 0.4 10 6.6 0.0 4.1 4 1 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cnd1 PF12717.7 RLN93753.1 - 0.0033 17.5 0.1 1.2 9.2 0.0 3.8 3 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Mo25 PF08569.11 RLN93753.1 - 0.012 15.0 0.0 0.68 9.2 0.0 2.4 2 1 0 2 2 2 0 Mo25-like V-ATPase_H_C PF11698.8 RLN93753.1 - 0.012 15.7 0.0 11 6.2 0.0 3.8 3 1 1 4 4 4 0 V-ATPase subunit H CLASP_N PF12348.8 RLN93753.1 - 0.064 12.8 0.4 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 CLASP N terminal CTNNBL PF08216.11 RLN93753.1 - 0.1 12.8 0.7 52 4.1 0.0 3.8 2 2 2 4 4 4 0 Catenin-beta-like, Arm-motif containing nuclear DDE_1 PF03184.19 RLN93754.1 - 7.3e-34 116.9 0.0 1.6e-33 115.8 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN93754.1 - 5.3e-11 42.4 0.1 1e-10 41.4 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Rhomboid PF01694.22 RLN93755.1 - 9.1e-13 48.5 0.1 4e-12 46.4 0.0 1.9 2 0 0 2 2 2 1 Rhomboid family AAA_28 PF13521.6 RLN93757.1 - 3.2e-22 79.5 0.0 4.6e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 RLN93757.1 - 0.00044 19.3 0.0 0.00071 18.6 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 RLN93757.1 - 0.0019 17.7 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DAP3 PF10236.9 RLN93757.1 - 0.083 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_30 PF13604.6 RLN93757.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RLN93757.1 - 0.16 11.7 0.0 6.6 6.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 RLN93757.1 - 0.19 11.6 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 NTPase QLQ PF08880.11 RLN93757.1 - 0.75 9.6 4.6 7.8 6.3 0.0 3.3 3 0 0 3 3 3 0 QLQ Lactamase_B_2 PF12706.7 RLN93758.1 - 8e-18 64.7 0.1 1.4e-17 63.9 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 RLN93758.1 - 0.45 10.5 2.7 1.5 8.8 1.9 2.3 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily Pkinase PF00069.25 RLN93759.1 - 7.7e-34 117.2 0.6 2.3e-33 115.7 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN93759.1 - 2.8e-27 95.7 0.0 4.7e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_6 PF13516.6 RLN93759.1 - 5.6e-05 22.9 20.6 0.26 11.4 0.1 5.3 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 RLN93759.1 - 0.00019 21.8 13.5 0.0015 18.9 1.9 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) Mre11_DNA_bind PF04152.14 RLN93759.1 - 0.14 12.4 4.0 0.32 11.3 4.0 1.5 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain LRR_1 PF00560.33 RLN93759.1 - 0.3 11.8 5.9 32 5.6 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat NIF PF03031.18 RLN93760.1 - 2.1e-47 160.8 0.0 2.6e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 RLN93760.1 - 0.0033 17.8 0.0 0.0055 17.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Resolvase PF00239.21 RLN93760.1 - 0.022 14.9 0.5 0.064 13.4 0.0 1.9 3 0 0 3 3 3 0 Resolvase, N terminal domain DivIVA PF05103.13 RLN93761.1 - 0.0051 16.9 2.6 0.0097 16.0 2.6 1.4 1 0 0 1 1 1 1 DivIVA protein RNA_pol_Rpc4 PF05132.14 RLN93761.1 - 4.7 7.6 14.0 3 8.3 0.1 3.8 4 0 0 4 4 4 0 RNA polymerase III RPC4 SHIPPO-rpt PF07004.12 RLN93762.1 - 2.6e-09 37.5 19.4 0.077 13.9 1.2 7.3 8 0 0 8 8 8 5 Sperm-tail PG-rich repeat Cyclin_N PF00134.23 RLN93763.1 - 4.7e-07 29.6 0.2 9.2e-07 28.7 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain WGR PF05406.15 RLN93764.1 - 4.8e-18 65.0 0.3 2.5e-17 62.7 0.1 1.9 2 0 0 2 2 2 1 WGR domain PARP_reg PF02877.14 RLN93765.1 - 6.2e-29 100.8 0.1 8.7e-29 100.4 0.1 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain Rubis-subs-bind PF09273.11 RLN93766.1 - 1.9e-14 54.5 0.0 3.8e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 RLN93766.1 - 1.3e-06 28.9 0.0 3.2e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 SET domain PARP PF00644.20 RLN93767.1 - 5.7e-52 176.2 7.6 9.2e-24 84.1 0.0 4.6 4 1 1 5 5 5 4 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 RLN93767.1 - 1.6e-17 63.9 0.2 2.5e-17 63.2 0.2 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 RLN93767.1 - 8.5e-15 54.6 1.4 2.4e-14 53.1 0.1 2.2 2 0 0 2 2 2 1 WGR domain Ank_2 PF12796.7 RLN93768.1 - 6.9e-40 135.5 10.3 4.2e-07 30.5 0.1 10.5 7 4 1 9 9 9 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN93768.1 - 2.3e-38 130.1 12.6 9.4e-05 22.9 0.1 12.6 9 4 4 13 13 13 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN93768.1 - 7.2e-31 105.8 13.5 4e-08 33.4 0.1 9.9 9 1 1 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN93768.1 - 2.8e-21 73.3 19.2 0.0061 17.0 0.0 14.8 18 0 0 18 18 18 5 Ankyrin repeat Ank PF00023.30 RLN93768.1 - 2.2e-19 69.0 25.1 0.0034 17.8 0.1 14.7 17 0 0 17 17 17 4 Ankyrin repeat PAP_assoc PF03828.19 RLN93769.1 - 4.6e-15 55.6 0.2 1.2e-14 54.3 0.2 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 RLN93769.1 - 1.3e-05 25.4 0.0 3.2e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain RRM_1 PF00076.22 RLN93770.1 - 0.00049 19.9 0.0 0.0055 16.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DER1 PF04511.15 RLN93771.1 - 2.1e-26 93.1 0.2 3.2e-26 92.4 0.2 1.3 1 1 0 1 1 1 1 Der1-like family zf-BED PF02892.15 RLN93772.1 - 0.0025 17.8 0.0 0.014 15.4 0.0 2.3 2 0 0 2 2 2 1 BED zinc finger Dimer_Tnp_hAT PF05699.14 RLN93772.1 - 0.0048 16.6 0.0 0.021 14.6 0.0 2.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region IATP PF04568.12 RLN93772.1 - 0.37 11.2 0.0 0.37 11.2 0.0 3.6 3 1 0 3 3 3 0 Mitochondrial ATPase inhibitor, IATP DUF4674 PF15719.5 RLN93772.1 - 4.6 7.2 6.1 8.7 6.3 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) CWC25 PF12542.8 RLN93772.1 - 4.9 8.1 5.4 1.4 9.8 0.4 2.5 2 0 0 2 2 2 0 Pre-mRNA splicing factor VPS13_C PF16909.5 RLN93773.1 - 3.8e-54 183.2 0.5 1.9e-50 171.1 0.0 2.7 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Glyco_transf_22 PF03901.17 RLN93773.1 - 8.3e-54 183.4 15.8 2.3e-29 102.9 2.8 3.2 2 1 1 3 3 3 3 Alg9-like mannosyltransferase family SHR-BD PF06650.12 RLN93773.1 - 1.9e-38 132.4 0.3 2.5e-31 109.1 0.0 4.4 5 0 0 5 5 5 3 SHR-binding domain of vacuolar-sorting associated protein 13 PH PF00169.29 RLN93773.1 - 1.2e-17 64.3 0.1 8.7e-08 32.6 0.0 4.1 3 0 0 3 3 3 3 PH domain Chorein_N PF12624.7 RLN93773.1 - 1.3e-12 47.8 0.0 4.6e-12 46.1 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 RLN93773.1 - 3.3e-06 27.3 0.0 1.9e-05 24.9 0.0 2.3 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain DEP PF00610.21 RLN93773.1 - 0.00071 19.6 0.0 0.0057 16.7 0.0 2.5 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_3 PF14593.6 RLN93773.1 - 0.01 15.9 0.0 6.3 7.0 0.0 2.9 2 0 0 2 2 2 0 PH domain PMT_2 PF13231.6 RLN93773.1 - 0.022 15.0 2.1 0.05 13.8 2.1 1.5 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase PDZ_6 PF17820.1 RLN93773.1 - 0.045 13.6 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 PDZ domain C2 PF00168.30 RLN93773.1 - 0.075 13.3 0.0 0.27 11.5 0.0 2.1 1 0 0 1 1 1 0 C2 domain PDZ PF00595.24 RLN93773.1 - 0.078 13.3 0.1 0.27 11.6 0.0 2.0 2 0 0 2 2 1 0 PDZ domain PH_11 PF15413.6 RLN93773.1 - 0.1 13.0 0.8 11 6.5 0.3 3.9 3 0 0 3 3 3 0 Pleckstrin homology domain DER1 PF04511.15 RLN93774.1 - 2.6e-16 60.1 3.6 2.8e-16 60.0 3.6 1.0 1 0 0 1 1 1 1 Der1-like family NIF PF03031.18 RLN93775.1 - 1.5e-47 161.2 0.0 2.2e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Defensin_2 PF01097.18 RLN93775.1 - 0.073 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Arthropod defensin EMP24_GP25L PF01105.24 RLN93776.1 - 3.7e-14 53.1 0.0 4.8e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Trypsin PF00089.26 RLN93777.1 - 2.6e-17 63.4 2.0 4.6e-17 62.6 2.0 1.4 1 0 0 1 1 1 1 Trypsin Cyclin_N PF00134.23 RLN93777.1 - 2.7e-07 30.4 5.1 3.9e-07 29.8 0.3 2.7 3 0 0 3 3 3 1 Cyclin, N-terminal domain DHC_N1 PF08385.12 RLN93778.1 - 9e-183 608.9 17.5 9e-183 608.9 17.5 2.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 RLN93778.1 - 7e-144 478.8 0.0 5.7e-143 475.8 0.0 2.6 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN93778.1 - 3.7e-112 375.4 16.8 3.7e-112 375.4 16.8 3.0 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 RLN93778.1 - 4.1e-60 202.4 0.8 3.1e-54 183.2 0.0 3.9 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 RLN93778.1 - 9.4e-20 71.0 0.0 5.4e-19 68.5 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RLN93778.1 - 1.6e-09 37.9 0.0 8e-05 22.7 0.0 4.4 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.29 RLN93778.1 - 8e-07 29.5 0.4 0.24 11.8 0.0 3.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN93778.1 - 8.9e-05 22.9 0.0 4.8 7.5 0.0 4.5 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 RLN93778.1 - 0.00041 20.6 0.4 8.3 6.7 0.1 4.0 3 0 0 3 3 3 0 AAA domain DUF3583 PF12126.8 RLN93778.1 - 0.00069 19.2 0.8 0.0023 17.4 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3583) AAA_18 PF13238.6 RLN93778.1 - 0.005 17.4 0.1 4.5 7.8 0.0 4.2 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 RLN93778.1 - 0.0061 16.9 1.4 17 5.7 0.1 4.0 3 0 0 3 3 3 0 AAA domain AAA_lid_1 PF17857.1 RLN93778.1 - 0.0076 16.4 0.1 0.086 13.1 0.1 3.0 2 0 0 2 2 2 1 AAA+ lid domain RNA_helicase PF00910.22 RLN93778.1 - 0.013 15.9 0.2 3.3 8.1 0.0 3.9 3 0 0 3 3 2 0 RNA helicase T2SSE PF00437.20 RLN93778.1 - 0.015 14.4 0.0 3.5 6.6 0.0 3.4 3 0 0 3 3 3 0 Type II/IV secretion system protein 5_3_exonuc PF01367.20 RLN93778.1 - 0.056 14.0 0.0 0.89 10.2 0.0 3.3 2 1 0 2 2 1 0 5'-3' exonuclease, C-terminal SAM fold AAA_29 PF13555.6 RLN93778.1 - 0.085 12.6 0.1 0.42 10.4 0.1 2.2 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 RLN93778.1 - 0.27 11.3 1.6 13 5.9 0.2 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 RLN93778.1 - 0.27 11.7 0.0 0.27 11.7 0.0 5.2 4 2 0 4 4 2 0 AAA domain AAA_33 PF13671.6 RLN93778.1 - 0.43 10.7 5.1 12 6.1 0.0 3.5 4 0 0 4 4 2 0 AAA domain UTP15_C PF09384.10 RLN93778.1 - 1.6 8.4 4.1 4.2 7.1 0.1 3.4 3 0 0 3 3 3 0 UTP15 C terminal AAA_11 PF13086.6 RLN93778.1 - 2 8.1 4.5 27 4.4 0.0 4.0 4 0 0 4 4 3 0 AAA domain CagY_I PF14585.6 RLN93778.1 - 2.1 8.5 3.7 1.1 9.3 0.1 2.4 3 0 0 3 3 2 0 CagY type 1 repeat AAA_30 PF13604.6 RLN93778.1 - 4 7.1 5.6 41 3.8 0.6 3.3 3 0 0 3 3 3 0 AAA domain Q_salvage PF10343.9 RLN93779.1 - 4.2e-37 128.2 0.0 1.4e-29 103.6 0.0 2.1 1 1 1 2 2 2 2 Potential Queuosine, Q, salvage protein family ABC_tran PF00005.27 RLN93780.1 - 2.9e-28 99.1 0.0 5.3e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 RLN93780.1 - 1.1e-19 70.8 31.3 1.3e-18 67.3 31.3 2.4 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 RLN93780.1 - 8.3e-13 48.8 0.1 2.5e-08 34.1 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN93780.1 - 0.0022 17.9 0.1 0.0042 17.0 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 RLN93780.1 - 0.0023 18.5 0.0 0.004 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 RLN93780.1 - 0.018 14.8 0.1 0.043 13.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 RLN93780.1 - 0.032 13.9 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 RLN93780.1 - 0.084 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 RLN93780.1 - 0.094 12.1 0.0 2.4 7.5 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DLIC PF05783.11 RLN93780.1 - 0.16 10.8 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) FA_desaturase PF00487.24 RLN93780.1 - 2.6 7.8 5.7 5.5 6.8 5.7 1.5 1 0 0 1 1 1 0 Fatty acid desaturase ABC2_membrane PF01061.24 RLN93780.1 - 3.3 7.1 32.6 0.81 9.1 22.4 2.6 3 0 0 3 3 3 0 ABC-2 type transporter LAT PF15234.6 RLN93782.1 - 0.21 11.3 3.5 0.28 10.9 3.5 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells tRNA-synt_1b PF00579.25 RLN93783.1 - 9.1e-98 327.2 0.0 3.9e-51 174.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) PP2C PF00481.21 RLN93783.1 - 1.7e-06 27.9 0.0 3.6e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RLN93783.1 - 0.062 12.9 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein phosphatase 2C DUF5534 PF17686.1 RLN93783.1 - 0.14 12.4 1.3 0.28 11.4 1.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5534) Lipoprotein_20 PF13942.6 RLN93783.1 - 0.33 10.8 4.2 3.6 7.5 0.1 3.1 3 1 1 4 4 4 0 YfhG lipoprotein YfhO PF09586.10 RLN93784.1 - 0.021 13.1 1.1 0.12 10.6 1.1 1.8 1 1 0 1 1 1 0 Bacterial membrane protein YfhO PI3Ka PF00613.20 RLN93784.1 - 0.18 11.2 0.1 0.26 10.7 0.1 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) HTH_Tnp_Tc5 PF03221.16 RLN93785.1 - 0.0035 17.3 0.0 0.0071 16.4 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF1389 PF07146.11 RLN93785.1 - 0.0051 16.1 0.3 0.006 15.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1389) Ferrochelatase PF00762.19 RLN93785.1 - 0.016 14.3 0.1 0.019 14.1 0.1 1.1 1 0 0 1 1 1 0 Ferrochelatase DUF4304 PF14137.6 RLN93785.1 - 0.12 12.6 0.1 0.15 12.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4304) Phage_rep_O PF04492.13 RLN93786.1 - 0.7 10.5 4.7 5 7.8 2.3 2.8 2 1 0 2 2 2 0 Bacteriophage replication protein O Tho2 PF11262.8 RLN93786.1 - 1.2 8.3 22.0 0.71 9.0 7.7 2.5 1 1 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 TarH PF02203.15 RLN93786.1 - 8.9 6.2 20.2 4.5 7.2 0.9 3.2 1 1 2 3 3 3 0 Tar ligand binding domain homologue TAXi_N PF14543.6 RLN93788.1 - 0.042 14.1 0.8 0.093 13.0 0.8 1.5 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal Filament PF00038.21 RLN93788.1 - 0.043 13.4 6.4 0.096 12.3 6.4 1.5 1 0 0 1 1 1 0 Intermediate filament protein Fez1 PF06818.15 RLN93788.1 - 8.9 6.7 11.9 0.49 10.8 3.1 2.3 2 0 0 2 2 2 0 Fez1 DUF659 PF04937.15 RLN93789.1 - 4.6e-15 55.8 0.2 1.4e-14 54.2 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 RLN93789.1 - 3.6e-05 23.5 0.0 9.8e-05 22.1 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ZZ PF00569.17 RLN93794.1 - 0.0028 17.4 3.0 0.0044 16.8 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type UCH PF00443.29 RLN93795.1 - 2.2e-45 155.2 0.0 2.7e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN93795.1 - 5.2e-08 32.9 0.2 3.1e-06 27.0 0.2 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 RLN93795.1 - 0.0017 17.8 0.3 0.029 13.8 0.1 2.4 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Galactosyl_T PF01762.21 RLN93796.1 - 2.5e-22 79.6 0.0 3.5e-20 72.7 0.0 2.3 2 0 0 2 2 2 2 Galactosyltransferase Pkinase PF00069.25 RLN93797.1 - 3.5e-08 33.1 0.0 4.9e-08 32.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN93797.1 - 0.00038 19.8 0.0 0.0023 17.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase TIP41 PF04176.13 RLN93798.1 - 6e-57 191.9 0.2 9.4e-57 191.2 0.2 1.3 1 0 0 1 1 1 1 TIP41-like family COMM_domain PF07258.14 RLN93798.1 - 1.4e-09 37.9 0.1 4.5e-09 36.3 0.1 1.9 1 0 0 1 1 1 1 COMM domain CK_II_beta PF01214.18 RLN93799.1 - 1.4e-76 256.3 0.1 2e-76 255.8 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit FYDLN_acid PF09538.10 RLN93799.1 - 0.054 14.2 13.5 0.13 13.0 11.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Rhabdo_ncap PF00945.18 RLN93799.1 - 0.097 11.5 4.6 0.13 11.1 4.6 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Pox_Ag35 PF03286.14 RLN93799.1 - 0.15 11.9 6.1 0.26 11.1 6.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RRN3 PF05327.11 RLN93799.1 - 0.16 10.4 4.5 0.2 10.2 4.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 RLN93799.1 - 0.22 10.8 14.4 0.5 9.6 14.4 1.6 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 RLN93799.1 - 0.25 10.4 18.9 0.36 9.9 18.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.12 RLN93799.1 - 0.29 10.5 10.9 0.41 10.0 10.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CENP-B_dimeris PF09026.10 RLN93799.1 - 0.38 11.2 16.0 0.84 10.1 16.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TFB6 PF17110.5 RLN93799.1 - 0.41 10.4 4.3 0.65 9.7 4.3 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH BUD22 PF09073.10 RLN93799.1 - 0.43 9.9 10.0 0.61 9.4 10.0 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 RLN93799.1 - 0.49 9.8 13.3 0.041 13.3 8.8 1.5 2 0 0 2 2 2 0 SDA1 FAM176 PF14851.6 RLN93799.1 - 0.61 9.7 7.2 1.2 8.8 7.2 1.5 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 RLN93799.1 - 0.98 7.4 18.4 1.4 7.0 18.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 RLN93799.1 - 1.1 7.4 13.6 1.5 7.0 13.6 1.2 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 RLN93799.1 - 1.2 9.0 11.5 2.1 8.2 11.5 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.12 RLN93799.1 - 1.4 8.6 14.7 2.1 8.0 14.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 RLN93799.1 - 2.2 8.3 8.7 4.6 7.3 8.7 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.14 RLN93799.1 - 2.5 6.3 11.8 3.5 5.8 11.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 RLN93799.1 - 2.8 7.3 11.6 4 6.7 11.6 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PBP1_TM PF14812.6 RLN93799.1 - 5.7 7.4 11.3 1.2 9.5 7.7 1.7 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GCIP PF13324.6 RLN93799.1 - 6.8 6.2 8.6 4.9 6.7 7.0 1.5 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting PPP4R2 PF09184.11 RLN93799.1 - 9.6 5.7 14.5 14 5.2 14.5 1.2 1 0 0 1 1 1 0 PPP4R2 ASCH PF04266.14 RLN93800.1 - 0.016 15.8 0.0 0.046 14.3 0.0 1.7 1 1 0 1 1 1 0 ASCH domain PP2C PF00481.21 RLN93801.1 - 2.5e-38 132.2 0.0 1.8e-37 129.4 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 RLN93801.1 - 0.095 12.6 0.2 3.3 7.6 0.1 2.6 2 1 1 3 3 3 0 Stage II sporulation protein E (SpoIIE) EF-hand_7 PF13499.6 RLN93802.1 - 3.8e-14 52.9 0.3 3.6e-11 43.4 0.6 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN93802.1 - 6.8e-13 47.2 4.8 5.5e-06 25.6 1.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 RLN93802.1 - 4.6e-12 45.6 2.2 6e-09 35.6 0.7 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RLN93802.1 - 4.2e-09 35.6 0.6 0.0019 18.0 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RLN93802.1 - 0.0039 16.6 3.3 0.54 9.9 0.6 2.7 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 RLN93802.1 - 0.01 16.2 0.1 0.029 14.7 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain SPRY PF00622.28 RLN93803.1 - 0.00026 21.1 0.0 0.00073 19.6 0.0 1.8 2 0 0 2 2 2 1 SPRY domain DUF5521 PF17659.1 RLN93806.1 - 6.1e-07 27.7 0.0 2.3e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5521) Rep-A_N PF04057.12 RLN93806.1 - 0.043 13.8 0.0 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 Replication factor-A protein 1, N-terminal domain Claudin_3 PF06653.11 RLN93807.1 - 0.00092 19.2 7.7 0.027 14.4 1.7 2.5 2 1 1 3 3 3 2 Tight junction protein, Claudin-like PMP22_Claudin PF00822.20 RLN93807.1 - 0.012 15.5 9.0 0.17 11.8 2.8 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 RLN93807.1 - 1.3 8.8 13.6 33 4.1 13.6 2.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Ras PF00071.22 RLN93808.1 - 4.2e-54 182.5 0.0 4.9e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN93808.1 - 4.4e-22 78.6 0.0 6.3e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN93808.1 - 1.2e-09 37.9 0.0 1.5e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RLN93808.1 - 0.0044 16.6 0.0 0.0087 15.6 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Abhydrolase_1 PF00561.20 RLN93809.1 - 5.9e-06 26.1 0.1 0.016 14.9 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN93809.1 - 0.0024 17.2 0.3 0.49 9.6 0.1 2.4 1 1 2 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN93809.1 - 0.0075 16.9 3.0 0.77 10.3 0.1 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 RLN93809.1 - 0.026 14.1 0.1 3.2 7.3 0.0 3.0 2 1 1 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Galactosyl_T PF01762.21 RLN93810.1 - 5.6e-26 91.6 0.0 9.2e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase PH PF00169.29 RLN93810.1 - 1.2e-08 35.4 0.1 7.3e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 RLN93810.1 - 9.6e-06 25.8 0.1 0.0012 19.1 0.0 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain Galactosyl_T PF01762.21 RLN93811.1 - 4.2e-22 78.9 0.2 2.9e-21 76.2 0.2 2.1 1 1 0 1 1 1 1 Galactosyltransferase Glyco_transf_10 PF00852.19 RLN93811.1 - 4.1e-20 72.2 0.0 9.5e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term 3HCDH_N PF02737.18 RLN93813.1 - 8e-55 185.5 0.2 8e-55 185.5 0.2 2.0 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 RLN93813.1 - 4.8e-44 150.6 3.7 1.4e-43 149.0 2.4 2.4 2 1 1 3 3 3 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 RLN93813.1 - 3.5e-34 117.3 0.0 2.2e-23 82.7 0.0 3.4 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 RLN93813.1 - 8.3e-30 104.4 1.3 8.3e-30 104.4 1.3 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 RLN93813.1 - 0.02 15.1 0.1 0.063 13.4 0.1 2.0 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.27 RLN93813.1 - 0.034 14.7 0.4 0.11 13.1 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 RLN93813.1 - 0.04 13.2 0.1 0.073 12.3 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RLN93813.1 - 0.078 13.2 0.1 0.25 11.6 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ARL2_Bind_BART PF11527.8 RLN93814.1 - 3.2e-33 114.3 1.2 6.3e-33 113.3 0.0 2.1 2 1 0 2 2 2 1 The ARF-like 2 binding protein BART DUF572 PF04502.13 RLN93814.1 - 2.7 7.5 28.3 4.4 6.8 28.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) LMBR1 PF04791.16 RLN93814.1 - 3.6 6.4 10.3 5 5.9 10.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Cation_ATPase_C PF00689.21 RLN93816.1 - 1e-45 155.7 0.5 1e-45 155.7 0.5 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 RLN93816.1 - 4.5e-32 111.0 4.4 4.6e-22 78.4 1.6 3.6 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase PF13246.6 RLN93816.1 - 2.2e-18 66.1 0.1 4.7e-18 65.1 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RLN93816.1 - 2.7e-12 47.4 0.6 1e-10 42.3 0.6 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RLN93816.1 - 1.2e-11 44.1 0.0 2.8e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RLN93816.1 - 0.00097 18.9 0.9 0.0027 17.5 0.3 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4064 PF13273.6 RLN93816.1 - 0.11 12.7 10.6 0.41 10.9 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) MFS_1 PF07690.16 RLN93817.1 - 1.1e-24 87.0 29.4 1.7e-24 86.4 29.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SPX PF03105.19 RLN93817.1 - 1.3e-09 38.5 8.2 1.7e-06 28.2 0.5 2.4 1 1 0 2 2 2 2 SPX domain Sugar_tr PF00083.24 RLN93817.1 - 1.9e-05 23.8 14.1 0.00011 21.2 13.8 2.0 1 1 1 2 2 2 1 Sugar (and other) transporter Thiolase_N PF00108.23 RLN93818.1 - 2.4e-51 174.6 1.7 1.4e-48 165.5 0.7 2.4 2 1 1 3 3 3 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 RLN93818.1 - 3.2e-22 78.5 5.7 1.9e-20 72.8 5.7 2.5 1 1 0 1 1 1 1 Thiolase, C-terminal domain Ins_allergen_rp PF06757.13 RLN93819.1 - 0.02 14.9 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification RCC1 PF00415.18 RLN93820.1 - 2.1e-21 76.3 0.0 8e-10 39.2 0.0 2.1 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN93820.1 - 3.6e-10 39.4 1.1 1.9e-05 24.3 0.0 3.2 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat LUC7 PF03194.15 RLN93821.1 - 0.016 14.9 7.7 0.02 14.6 7.7 1.2 1 0 0 1 1 1 0 LUC7 N_terminus ADIP PF11559.8 RLN93821.1 - 0.021 14.9 27.4 0.82 9.7 13.3 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 RLN93821.1 - 0.025 15.2 15.1 0.078 13.6 1.7 2.6 1 1 1 2 2 2 0 Initiation control protein YabA MAD PF05557.13 RLN93821.1 - 0.046 12.1 19.7 0.062 11.7 19.7 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF1664 PF07889.12 RLN93821.1 - 0.054 13.5 7.3 0.079 13.0 6.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Nup88 PF10168.9 RLN93821.1 - 0.058 11.2 7.6 0.083 10.7 7.6 1.2 1 0 0 1 1 1 0 Nuclear pore component HOOK PF05622.12 RLN93821.1 - 0.085 11.0 21.4 0.11 10.6 21.4 1.1 1 0 0 1 1 1 0 HOOK protein V_ATPase_I PF01496.19 RLN93821.1 - 0.09 10.7 8.3 0.12 10.2 8.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family K-box PF01486.17 RLN93821.1 - 0.17 12.1 16.6 0.7 10.1 2.3 3.5 2 1 1 3 3 3 0 K-box region APG6_N PF17675.1 RLN93821.1 - 0.17 12.4 31.9 0.035 14.6 20.9 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region MtrB PF05440.12 RLN93821.1 - 0.23 11.9 0.1 0.75 10.2 0.0 1.8 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Exonuc_VII_L PF02601.15 RLN93821.1 - 0.25 10.9 10.7 0.36 10.3 10.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit XhlA PF10779.9 RLN93821.1 - 0.27 11.5 9.0 3 8.1 2.1 2.7 2 0 0 2 2 2 0 Haemolysin XhlA Prominin PF05478.11 RLN93821.1 - 0.6 8.0 13.3 0.83 7.5 13.3 1.1 1 0 0 1 1 1 0 Prominin TMF_DNA_bd PF12329.8 RLN93821.1 - 0.71 9.9 21.2 0.12 12.4 6.8 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF16 PF01519.16 RLN93821.1 - 0.83 10.2 14.8 0.059 13.9 7.7 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 ATG16 PF08614.11 RLN93821.1 - 0.88 9.8 27.4 1.4 9.1 26.6 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Prefoldin_2 PF01920.20 RLN93821.1 - 1.2 9.1 23.8 0.59 10.1 3.5 3.4 2 1 1 3 3 3 0 Prefoldin subunit bZIP_1 PF00170.21 RLN93821.1 - 1.4 9.0 15.7 1 9.5 0.7 3.5 2 1 1 3 3 3 0 bZIP transcription factor Syntaxin-6_N PF09177.11 RLN93821.1 - 1.5 9.4 19.3 5.4 7.6 5.6 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4407 PF14362.6 RLN93821.1 - 1.9 7.7 15.5 2.7 7.2 15.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Synaptobrevin PF00957.21 RLN93821.1 - 2 8.3 6.4 2.6 7.9 1.2 2.7 2 1 0 2 2 2 0 Synaptobrevin bZIP_2 PF07716.15 RLN93821.1 - 2 8.5 28.5 0.72 10.0 6.2 3.5 3 0 0 3 3 3 0 Basic region leucine zipper Fib_alpha PF08702.10 RLN93821.1 - 2.2 8.5 11.9 4.4 7.5 11.3 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF5082 PF16888.5 RLN93821.1 - 2.2 8.6 16.2 2.6 8.4 3.3 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) GAS PF13851.6 RLN93821.1 - 2.2 7.6 25.7 2.9 7.2 21.5 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 RLN93821.1 - 2.4 8.2 28.3 1.7 8.7 14.3 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 RLN93821.1 - 2.6 8.1 25.1 11 6.0 25.0 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KASH_CCD PF14662.6 RLN93821.1 - 2.7 7.8 27.9 0.72 9.6 11.6 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Macoilin PF09726.9 RLN93821.1 - 2.7 6.4 12.1 3.7 6.0 12.1 1.2 1 0 0 1 1 1 0 Macoilin family Fmp27_WPPW PF10359.9 RLN93821.1 - 2.9 6.6 15.9 0.063 12.1 3.9 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Jnk-SapK_ap_N PF09744.9 RLN93821.1 - 3.2 7.9 27.4 7.4 6.8 15.2 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Ax_dynein_light PF10211.9 RLN93821.1 - 3.3 7.6 22.4 5.3 7.0 14.5 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain FlaC_arch PF05377.11 RLN93821.1 - 3.3 8.2 6.8 23 5.5 0.2 3.0 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.12 RLN93821.1 - 3.6 7.6 12.4 36 4.4 8.5 2.5 1 1 1 2 2 2 0 Laminin Domain II Cnn_1N PF07989.11 RLN93821.1 - 5.7 7.2 18.2 2.3 8.5 5.3 2.9 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Mt_ATP-synt_D PF05873.12 RLN93821.1 - 7.8 6.3 8.9 16 5.4 0.8 2.2 1 1 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Fzo_mitofusin PF04799.13 RLN93821.1 - 7.9 6.0 16.1 0.87 9.1 2.3 2.4 1 1 1 2 2 2 0 fzo-like conserved region DUF465 PF04325.13 RLN93821.1 - 8.1 6.6 13.0 0.49 10.5 1.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF465) AAA_13 PF13166.6 RLN93821.1 - 8.3 4.9 14.6 18 3.8 14.6 1.5 1 1 0 1 1 1 0 AAA domain DUF4337 PF14235.6 RLN93821.1 - 8.8 6.4 19.3 8.9 6.4 5.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Elicitin PF00964.17 RLN93822.1 - 1.2e-11 44.5 2.4 1.6e-11 44.1 2.4 1.2 1 0 0 1 1 1 1 Elicitin Aa_trans PF01490.18 RLN93823.1 - 8.2e-53 179.6 15.7 1.2e-52 179.0 15.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein GTP_EFTU PF00009.27 RLN93823.1 - 1.8e-30 105.9 0.3 4.3e-30 104.7 0.3 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 RLN93823.1 - 5e-12 45.9 0.3 1.7e-11 44.2 0.3 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 RLN93823.1 - 1.7e-07 31.3 0.0 3.9e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RLN93823.1 - 3.5e-06 27.0 0.0 0.00088 19.2 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase MeaB PF03308.16 RLN93823.1 - 0.0055 15.7 0.7 0.038 13.0 0.2 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 RLN93823.1 - 0.01 15.6 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 RLN93823.1 - 0.039 13.5 0.2 0.16 11.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 RLN93823.1 - 0.19 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Septin Mito_carr PF00153.27 RLN93824.1 - 8.8e-51 169.8 5.8 8.5e-20 70.5 0.1 3.8 3 1 1 4 4 4 4 Mitochondrial carrier protein ASFV_L11L PF05293.11 RLN93824.1 - 0.058 13.7 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 African swine fever virus (ASFV) L11L protein Peptidase_M76 PF09768.9 RLN93826.1 - 1.4e-40 138.9 2.2 1.7e-40 138.5 2.2 1.0 1 0 0 1 1 1 1 Peptidase M76 family Peptidase_M91 PF14891.6 RLN93826.1 - 0.081 13.2 0.1 0.1 12.9 0.1 1.1 1 0 0 1 1 1 0 Effector protein NEMP PF10225.9 RLN93827.1 - 0.011 15.4 1.2 0.016 14.8 1.2 1.2 1 0 0 1 1 1 0 NEMP family GCV_H PF01597.19 RLN93827.1 - 0.2 11.6 0.0 0.68 9.8 0.0 1.9 1 1 0 1 1 1 0 Glycine cleavage H-protein PH PF00169.29 RLN93828.1 - 0.025 15.1 0.0 0.13 12.8 0.0 2.1 2 0 0 2 2 2 0 PH domain RNase_J_C PF17770.1 RLN93828.1 - 0.78 10.8 5.8 0.79 10.8 3.2 2.3 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain AT_hook PF02178.19 RLN93828.1 - 1.2 9.3 16.8 0.084 12.8 3.1 3.3 2 0 0 2 2 2 0 AT hook motif DUF2951 PF11166.8 RLN93828.1 - 1.6 9.0 7.6 5 7.4 7.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) TetR_C_14 PF17754.1 RLN93828.1 - 6 6.9 9.3 11 6.1 0.5 2.5 1 1 1 2 2 2 0 MftR C-terminal domain SMC_N PF02463.19 RLN93829.1 - 1.2e-55 188.3 33.4 9.6e-29 100.4 2.6 2.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 RLN93829.1 - 9.2e-27 93.7 0.2 1e-25 90.3 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 RLN93829.1 - 6.5e-12 45.8 0.8 6.5e-12 45.8 0.8 4.1 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 RLN93829.1 - 1.3e-11 44.9 5.0 1.6e-05 24.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RLN93829.1 - 6.1e-11 43.2 26.0 6.1e-11 43.2 26.0 6.5 3 2 1 4 4 4 1 AAA domain AAA_29 PF13555.6 RLN93829.1 - 0.0025 17.5 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 RLN93829.1 - 2.1 8.9 0.0 2.1 8.9 0.0 6.1 3 2 0 3 3 3 0 ABC transporter Aconitase PF00330.20 RLN93830.1 - 3.1e-141 471.5 0.0 3.7e-141 471.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.13 RLN93830.1 - 0.14 10.8 0.0 0.26 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Ribosomal_L12 PF00542.19 RLN93831.1 - 5.5e-27 93.9 10.3 1.2e-26 92.8 10.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 RLN93831.1 - 2e-10 40.2 1.1 2e-10 40.2 1.1 3.5 4 0 0 4 4 4 2 Ribosomal protein L7/L12 dimerisation domain DUF3072 PF11272.8 RLN93831.1 - 0.27 11.2 4.4 1.5 8.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) Ribophorin_I PF04597.14 RLN93832.1 - 1.1e-133 446.7 0.1 1.3e-133 446.5 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I Ribosomal_L3 PF00297.22 RLN93833.1 - 1.8e-179 596.4 8.8 2.1e-179 596.3 8.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 PCIF1_WW PF12237.8 RLN93834.1 - 7.5e-49 165.6 0.0 1.2e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain cNMP_binding PF00027.29 RLN93835.1 - 1.9e-18 66.3 4.0 7.2e-05 22.8 0.1 4.4 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain DUF1977 PF09320.11 RLN93835.1 - 7.4 6.9 9.9 0.48 10.7 1.2 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1977) Sugar_tr PF00083.24 RLN93836.1 - 1.5e-88 297.7 18.2 1.8e-88 297.4 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN93836.1 - 7.1e-28 97.5 25.9 9.8e-28 97.1 25.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily CytB6-F_Fe-S PF08802.10 RLN93836.1 - 0.63 10.1 8.2 2.4 8.2 0.2 3.1 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit DUF2583 PF10762.9 RLN93836.1 - 1.2 9.6 8.9 1 9.8 4.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) Sugar_tr PF00083.24 RLN93837.1 - 2e-88 297.3 18.1 2.4e-88 297.0 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN93837.1 - 7.5e-28 97.5 25.8 1e-27 97.0 25.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily CytB6-F_Fe-S PF08802.10 RLN93837.1 - 0.63 10.1 8.2 2.4 8.2 0.2 3.1 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit DUF2583 PF10762.9 RLN93837.1 - 1.3 9.5 8.9 1 9.8 4.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) MMS19_C PF12460.8 RLN93839.1 - 0.49 9.5 7.0 0.89 8.6 0.2 2.7 2 1 1 3 3 3 0 RNAPII transcription regulator C-terminal GGDEF_2 PF17853.1 RLN93839.1 - 0.76 10.1 5.1 82 3.5 0.1 3.5 2 1 2 4 4 4 0 GGDEF-like domain PEPCK_ATP PF01293.20 RLN93840.1 - 1e-12 47.5 0.0 1.2e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase GMC_oxred_N PF00732.19 RLN93843.1 - 1.9e-28 99.7 0.0 4.5e-28 98.5 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase PAN_4 PF14295.6 RLN93843.1 - 2.6e-18 65.7 13.9 3.5e-09 36.4 3.5 2.5 2 0 0 2 2 2 2 PAN domain PAN_1 PF00024.26 RLN93843.1 - 2.8e-11 43.2 5.5 4.7e-06 26.5 0.6 2.5 1 1 1 2 2 2 2 PAN domain GMC_oxred_C PF05199.13 RLN93843.1 - 2.1e-09 38.1 0.2 2.1e-09 38.1 0.2 1.8 2 0 0 2 2 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 RLN93843.1 - 7.4e-07 28.6 3.0 1.3e-05 24.5 3.0 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 RLN93843.1 - 7.8e-06 26.0 0.2 4.7e-05 23.5 0.0 2.5 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 RLN93843.1 - 0.00093 18.5 0.4 0.0048 16.2 0.3 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 RLN93843.1 - 0.0027 17.0 0.2 0.0067 15.7 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RLN93843.1 - 0.0078 15.5 0.1 0.012 14.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 RLN93843.1 - 0.036 12.8 0.2 0.063 12.0 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 RLN93843.1 - 0.068 12.4 0.4 0.14 11.4 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RLN93843.1 - 0.1 11.6 0.4 0.31 10.0 0.3 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 RLN93843.1 - 0.12 11.9 5.1 0.049 13.2 1.2 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase PBCV_basic_adap PF08789.10 RLN93844.1 - 7.8e-05 22.7 0.6 7.8e-05 22.7 0.6 2.2 3 0 0 3 3 3 1 PBCV-specific basic adaptor domain RAP1 PF07218.11 RLN93844.1 - 0.39 9.0 3.7 0.76 8.0 3.7 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Blo-t-5 PF11642.8 RLN93845.1 - 0.073 13.0 0.3 0.27 11.2 0.0 2.0 2 1 1 3 3 3 0 Mite allergen Blo t 5 Rhodanese PF00581.20 RLN93846.1 - 3.6e-23 82.1 0.0 9.6e-11 42.2 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain DUF2525 PF10733.9 RLN93846.1 - 0.0023 18.1 0.8 2.5 8.4 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF2525) KOW PF00467.29 RLN93846.1 - 0.0054 16.6 1.4 2.9 8.0 0.2 2.5 2 0 0 2 2 2 2 KOW motif LEH PF07858.12 RLN93846.1 - 0.11 12.6 0.1 20 5.3 0.0 2.3 2 0 0 2 2 2 0 Limonene-1,2-epoxide hydrolase catalytic domain PDZ_6 PF17820.1 RLN93846.1 - 0.11 12.3 0.1 19 5.2 0.0 2.5 2 0 0 2 2 2 0 PDZ domain SUFU PF05076.13 RLN93846.1 - 0.12 12.4 0.0 39 4.2 0.0 3.0 3 0 0 3 3 3 0 Suppressor of fused protein (SUFU) Peptidase_S9 PF00326.21 RLN93847.1 - 7.1e-23 81.2 0.0 2.8e-22 79.2 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 RLN93847.1 - 2e-11 43.5 1.2 0.00043 20.1 0.0 3.9 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.20 RLN93847.1 - 2.2e-08 34.1 0.7 2.9e-06 27.1 0.3 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN93847.1 - 0.00071 18.9 0.0 0.0022 17.3 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 RLN93847.1 - 0.047 13.2 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family COesterase PF00135.28 RLN93847.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family Acyl_transf_3 PF01757.22 RLN93848.1 - 8.4e-10 38.2 41.3 1.2e-09 37.7 41.3 1.2 1 0 0 1 1 1 1 Acyltransferase family DUF418 PF04235.12 RLN93848.1 - 0.0025 17.8 4.6 0.0025 17.8 4.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF418) Acyl_transf_3 PF01757.22 RLN93849.1 - 2.3e-11 43.4 36.0 3.3e-11 42.9 36.0 1.2 1 0 0 1 1 1 1 Acyltransferase family CHS5_N PF16892.5 RLN93849.1 - 0.042 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Chitin biosynthesis protein CHS5 N-terminus ALMT PF11744.8 RLN93850.1 - 1.2 7.8 5.0 1.7 7.4 5.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter CDK5_activator PF03261.15 RLN93850.1 - 3.3 7.2 8.2 4.9 6.6 8.2 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF4050 PF13259.6 RLN93850.1 - 3.8 7.8 15.9 12 6.2 15.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) CTD PF12815.7 RLN93850.1 - 7.6 7.2 9.3 0.6 10.7 0.2 2.8 2 1 0 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 APG6_N PF17675.1 RLN93851.1 - 1.8 9.1 78.0 0.075 13.6 18.4 5.7 4 2 1 5 5 5 0 Apg6 coiled-coil region DASH_Dam1 PF08653.10 RLN93851.1 - 3 7.7 10.2 1.2 8.9 1.0 4.0 3 0 0 3 3 3 0 DASH complex subunit Dam1 PBCV_basic_adap PF08789.10 RLN93852.1 - 0.00063 19.8 2.2 0.0026 17.8 0.3 2.6 2 0 0 2 2 2 1 PBCV-specific basic adaptor domain Phage_TAC_13 PF16459.5 RLN93852.1 - 0.019 15.4 0.0 0.05 14.1 0.0 1.7 1 0 0 1 1 1 0 Phage tail assembly chaperone, TAC RAP1 PF07218.11 RLN93852.1 - 0.37 9.0 7.0 0.55 8.4 7.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DNA_pol_E_B PF04042.16 RLN93853.1 - 4.3e-36 124.3 0.0 6.4e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 RLN93853.1 - 2.6e-28 98.7 0.0 4.7e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Pkinase PF00069.25 RLN93854.1 - 2.9e-48 164.5 0.0 5.8e-48 163.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN93854.1 - 3.6e-20 72.3 0.0 7.2e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN93854.1 - 2.9e-06 26.8 0.8 2.7e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN93854.1 - 0.00072 19.6 0.0 0.0019 18.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF724 PF05266.14 RLN93854.1 - 0.0029 17.5 3.4 0.0042 16.9 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF724) DUF4201 PF13870.6 RLN93854.1 - 0.42 10.3 5.7 0.62 9.8 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) TBCA PF02970.16 RLN93855.1 - 1.1e-25 89.7 3.0 1.3e-25 89.5 3.0 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A MMtag PF10159.9 RLN93855.1 - 0.033 14.5 1.0 0.059 13.7 1.0 1.3 1 0 0 1 1 1 0 Multiple myeloma tumor-associated Adenylsucc_synt PF00709.21 RLN93856.1 - 1e-170 568.2 0.0 1.3e-170 567.9 0.0 1.1 1 0 0 1 1 1 1 Adenylosuccinate synthetase PH PF00169.29 RLN93857.1 - 3.8e-06 27.4 0.0 8.6e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 PH domain Vps16_C PF04840.12 RLN93857.1 - 0.0022 17.1 0.2 1 8.3 0.1 2.2 2 0 0 2 2 2 2 Vps16, C-terminal region MSA-2c PF12238.8 RLN93857.1 - 0.84 9.6 3.4 1.5 8.8 3.4 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c GLTP PF08718.11 RLN93858.1 - 5.3e-27 94.9 0.2 1.7e-26 93.3 0.0 1.8 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) zf-AD PF07776.15 RLN93858.1 - 0.096 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) tRNA-synt_1 PF00133.22 RLN93859.1 - 1.1e-166 555.6 0.0 1.6e-166 555.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 RLN93859.1 - 3.3e-28 98.6 0.0 5.9e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 RLN93859.1 - 8e-20 70.9 0.0 1.2e-10 40.7 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.14 RLN93859.1 - 0.00013 21.7 1.1 0.00028 20.7 1.1 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.6 RLN93859.1 - 0.00034 20.2 0.0 0.00077 19.0 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 RLN93859.1 - 0.0021 17.5 0.0 1 8.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Ank_2 PF12796.7 RLN93860.1 - 6.5e-50 167.7 21.4 1.3e-10 41.7 1.5 6.8 2 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN93860.1 - 1.3e-38 126.6 23.3 0.016 15.7 0.0 13.4 14 0 0 14 14 14 11 Ankyrin repeat Ank_4 PF13637.6 RLN93860.1 - 2.3e-38 130.1 31.3 4.3e-07 30.4 0.9 9.0 5 3 4 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 RLN93860.1 - 1.1e-31 107.9 45.1 0.00015 22.0 2.8 11.7 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.6 RLN93860.1 - 1.8e-28 98.2 33.0 7.8e-08 32.4 0.3 11.1 5 3 7 12 12 12 9 Ankyrin repeats (many copies) ING PF12998.7 RLN93861.1 - 1.1e-16 61.2 2.4 2.2e-16 60.3 2.4 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 RLN93861.1 - 4.7e-05 23.2 8.0 8.2e-05 22.4 8.0 1.4 1 0 0 1 1 1 1 PHD-finger NdhM PF10664.9 RLN93861.1 - 0.017 15.3 0.1 0.03 14.6 0.1 1.3 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M PHD_2 PF13831.6 RLN93861.1 - 0.081 12.5 2.8 0.22 11.1 2.8 1.8 1 0 0 1 1 1 0 PHD-finger GCN5L1 PF06320.13 RLN93861.1 - 0.17 12.0 3.7 0.11 12.6 1.3 1.7 1 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) ABA_WDS PF02496.16 RLN93861.1 - 0.3 11.6 8.5 1.2 9.6 7.0 2.1 2 0 0 2 2 2 0 ABA/WDS induced protein HAUS6_N PF14661.6 RLN93861.1 - 0.38 10.3 2.3 0.54 9.8 2.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Kelch_1 PF01344.25 RLN93862.1 - 4.3e-12 45.4 2.6 0.02 14.5 0.0 6.6 7 0 0 7 7 7 3 Kelch motif Kelch_5 PF13854.6 RLN93862.1 - 1.2e-08 34.8 0.2 0.81 9.8 0.0 5.3 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 RLN93862.1 - 2.5e-05 24.4 9.3 0.045 14.1 0.1 5.9 7 0 0 7 7 7 2 Kelch motif Kelch_2 PF07646.15 RLN93862.1 - 0.0001 22.1 5.4 0.63 10.1 0.0 6.1 6 0 0 6 6 6 1 Kelch motif Kelch_4 PF13418.6 RLN93862.1 - 0.00046 20.1 10.2 0.36 10.9 0.0 5.3 6 0 0 6 6 6 2 Galactose oxidase, central domain EB PF01683.18 RLN93862.1 - 0.032 14.5 2.7 0.066 13.5 2.7 1.4 1 0 0 1 1 1 0 EB module LapA_dom PF06305.11 RLN93862.1 - 0.21 11.4 0.3 0.64 9.9 0.3 1.8 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TRAPP PF04051.16 RLN93863.1 - 4.1e-36 123.9 0.0 4.6e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Tubulin PF00091.25 RLN93864.1 - 4e-69 232.8 0.1 7.5e-69 231.9 0.1 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RLN93864.1 - 1.1e-48 164.6 0.0 2.6e-48 163.3 0.0 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 RLN93864.1 - 3.9e-05 23.9 0.0 9.6e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 RLN93864.1 - 0.0028 16.9 0.0 0.0076 15.5 0.0 1.7 2 0 0 2 2 2 1 Tubulin like DUF2817 PF10994.8 RLN93865.1 - 2e-71 241.2 0.0 2.3e-71 240.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) IlvC PF01450.19 RLN93866.1 - 1.2e-44 152.1 0.0 1.8e-34 119.1 0.0 2.1 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.12 RLN93866.1 - 0.00029 20.4 0.1 0.00067 19.3 0.1 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain zf-RING_2 PF13639.6 RLN93867.1 - 8.3e-08 32.4 7.0 8.3e-08 32.4 7.0 1.6 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 RLN93867.1 - 2.4e-06 27.7 3.2 6.1e-06 26.4 3.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain RINGv PF12906.7 RLN93867.1 - 0.00021 21.3 6.3 0.00021 21.3 6.3 2.0 2 0 0 2 2 2 1 RING-variant domain zf-ANAPC11 PF12861.7 RLN93867.1 - 0.0039 17.2 0.5 0.0079 16.2 0.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RLN93867.1 - 0.0057 16.5 4.6 0.015 15.2 4.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN93867.1 - 0.028 14.3 6.8 0.028 14.3 6.8 2.0 2 1 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN93867.1 - 0.06 13.2 6.9 0.15 12.0 6.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 RLN93867.1 - 0.082 12.9 0.5 0.13 12.2 0.5 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) FANCL_C PF11793.8 RLN93867.1 - 0.15 12.2 7.2 0.98 9.7 7.2 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain DUF5071 PF16804.5 RLN93867.1 - 0.19 12.0 0.0 0.48 10.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5071) zf-RING_4 PF14570.6 RLN93867.1 - 8.4 6.3 9.0 3.4 7.5 6.1 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RabGAP-TBC PF00566.18 RLN93868.1 - 4.5e-13 49.3 0.0 6.3e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Glucan_synthase PF02364.15 RLN93870.1 - 3.5e-187 624.2 20.9 5.2e-165 550.9 12.9 3.4 1 1 2 3 3 3 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 RLN93870.1 - 7.7e-24 84.5 6.3 1e-23 84.1 1.2 3.2 3 1 0 3 3 3 1 1,3-beta-glucan synthase subunit FKS1, domain-1 TROVE PF05731.11 RLN93870.1 - 0.025 13.6 0.1 2.9 6.8 0.0 2.3 2 0 0 2 2 2 0 TROVE domain EF-hand_5 PF13202.6 RLN93870.1 - 0.059 12.9 0.0 1.4 8.5 0.0 2.6 2 0 0 2 2 2 0 EF hand MtN3_slv PF03083.16 RLN93872.1 - 3.2e-32 110.4 8.8 4.1e-20 71.6 3.4 2.4 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RLN93872.1 - 0.013 15.3 1.6 5.9 6.7 0.0 3.5 3 0 0 3 3 3 0 PQ loop repeat HSP70 PF00012.20 RLN93873.1 - 9.3e-147 489.8 0.4 1.4e-146 489.2 0.4 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN93873.1 - 9.7e-07 27.9 0.1 1.9e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Smoa_sbd PF17885.1 RLN93873.1 - 0.12 12.5 0.0 2.5 8.3 0.0 2.8 2 0 0 2 2 2 0 Styrene monooxygenase A putative substrate binding domain Gon7 PF08738.10 RLN93873.1 - 0.22 11.6 2.6 0.28 11.3 0.2 2.5 3 0 0 3 3 3 0 Gon7 family HSP70 PF00012.20 RLN93874.1 - 6.3e-35 120.4 0.0 6.9e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Asp_Glu_race_2 PF14669.6 RLN93874.1 - 0.038 13.6 0.0 0.052 13.2 0.0 1.1 1 0 0 1 1 1 0 Putative aspartate racemase RVT_1 PF00078.27 RLN93875.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF966 PF06136.13 RLN93877.1 - 1.3 8.7 7.1 1.5 8.5 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Hydrolase_4 PF12146.8 RLN93878.1 - 1e-51 175.5 0.0 1.5e-51 175.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN93878.1 - 5.1e-13 50.1 3.0 6.7e-13 49.7 3.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN93878.1 - 1.9e-07 31.0 0.4 7.6e-05 22.5 0.4 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 RLN93878.1 - 0.00012 21.9 0.0 2.9 7.7 0.0 3.1 3 0 0 3 3 3 3 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 RLN93878.1 - 0.0015 18.1 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 RLN93878.1 - 0.022 14.3 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase PF00756.20 RLN93878.1 - 0.048 13.3 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase FYVE PF01363.21 RLN93879.1 - 0.00012 22.2 7.2 0.00028 21.0 7.2 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN93879.1 - 0.00095 19.4 5.7 0.0021 18.2 5.7 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger Prok-RING_4 PF14447.6 RLN93879.1 - 1.1 9.2 9.2 16 5.4 9.2 2.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Filament PF00038.21 RLN93880.1 - 3.7e-22 79.3 48.7 1.1e-21 77.7 48.7 2.3 1 1 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 RLN93880.1 - 3.3e-09 37.1 0.0 7.4e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Lamin Tail Domain HIP1_clath_bdg PF16515.5 RLN93880.1 - 0.02 15.5 8.5 0.02 15.5 8.5 5.0 2 1 2 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Prominin PF05478.11 RLN93880.1 - 0.56 8.1 17.9 0.87 7.5 17.9 1.3 1 0 0 1 1 1 0 Prominin Apolipoprotein PF01442.18 RLN93880.1 - 0.83 9.5 50.4 8.4 6.2 34.3 2.6 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF4407 PF14362.6 RLN93880.1 - 1.2 8.4 37.9 3.3 7.0 2.8 4.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) HMMR_N PF15905.5 RLN93880.1 - 3.2 7.2 50.4 0.16 11.4 12.6 3.9 2 1 2 4 4 4 0 Hyaluronan mediated motility receptor N-terminal WXG100 PF06013.12 RLN93880.1 - 4.1 7.7 12.6 1.5 9.1 0.8 4.8 3 2 1 4 4 4 0 Proteins of 100 residues with WXG DUF948 PF06103.11 RLN93880.1 - 8.6 6.7 8.3 1.3 9.3 0.3 3.1 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) ABC2_membrane PF01061.24 RLN93881.1 - 1.1e-09 38.1 14.4 1.1e-09 38.1 14.4 1.5 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN93881.1 - 2.1e-08 34.0 0.0 3.9e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 RLN93881.1 - 3.2 6.8 10.2 4.1 6.4 10.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DDE_1 PF03184.19 RLN93882.1 - 4.9e-11 42.6 0.0 1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN93882.1 - 7e-11 42.0 0.7 2e-10 40.6 0.1 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain MULE PF10551.9 RLN93883.1 - 3.4e-05 24.2 0.0 0.00012 22.4 0.0 1.9 1 0 0 1 1 1 1 MULE transposase domain Peptidase_C48 PF02902.19 RLN93883.1 - 0.0047 16.8 0.7 0.018 14.9 0.3 2.1 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Phage_tail_U PF06141.11 RLN93883.1 - 0.045 14.1 0.6 19 5.6 0.0 3.1 2 1 1 3 3 3 0 Phage minor tail protein U SWIM PF04434.17 RLN93883.1 - 0.078 12.7 0.1 0.24 11.1 0.1 1.8 1 0 0 1 1 1 0 SWIM zinc finger Peptidase_C5 PF00770.18 RLN93883.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Adenovirus endoprotease BING4CT PF08149.11 RLN93885.1 - 1.5e-38 130.4 0.0 2.2e-35 120.3 0.0 2.9 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 RLN93885.1 - 1.1e-07 32.0 0.0 1.6 9.1 0.0 4.5 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RLN93885.1 - 4.7e-06 27.2 0.0 0.043 14.7 0.0 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat Y2_Tnp PF04986.13 RLN93885.1 - 0.044 13.8 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative transposase HflK_N PF12221.8 RLN93885.1 - 0.095 12.7 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial membrane protein N terminal zf-C3HC4 PF00097.25 RLN93887.1 - 3.4e-09 36.4 8.3 8e-09 35.2 8.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FHA PF00498.26 RLN93887.1 - 5e-09 36.4 0.0 9.1e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-C3HC4_2 PF13923.6 RLN93887.1 - 1.9e-08 34.0 8.7 4.1e-08 32.9 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN93887.1 - 5.5e-08 33.0 9.6 5.5e-08 33.0 9.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 RLN93887.1 - 1e-07 32.0 11.6 2.3e-07 30.9 11.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 RLN93887.1 - 2.2e-07 30.6 4.9 5.6e-07 29.3 4.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN93887.1 - 2.8e-07 30.4 8.5 5.7e-07 29.4 8.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN93887.1 - 0.00027 20.8 7.4 0.00068 19.5 7.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RLN93887.1 - 0.0014 18.4 7.2 0.0039 17.0 7.2 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 RLN93887.1 - 0.002 18.4 9.6 0.0073 16.6 9.6 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 RLN93887.1 - 0.012 15.5 2.7 0.027 14.3 2.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 RLN93887.1 - 0.11 12.6 2.0 0.33 11.0 2.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 RLN93887.1 - 0.2 11.8 3.1 0.48 10.6 3.1 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 RLN93887.1 - 1.2 9.0 6.6 3.7 7.4 6.6 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 RLN93887.1 - 1.6 8.6 7.3 5.9 6.8 7.5 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PQQ_3 PF13570.6 RLN93888.1 - 0.018 15.5 0.7 0.32 11.5 0.3 2.9 3 0 0 3 3 3 0 PQQ-like domain TTL PF03133.15 RLN93889.1 - 4.5e-61 206.6 0.2 9.1e-61 205.6 0.2 1.4 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RLN93889.1 - 0.057 12.7 0.1 2.6 7.2 0.0 2.4 2 0 0 2 2 2 0 YheC/D like ATP-grasp PWI PF01480.17 RLN93891.1 - 1.2e-26 92.8 0.3 3.2e-26 91.4 0.3 1.8 1 0 0 1 1 1 1 PWI domain MMADHC PF10229.9 RLN93891.1 - 6.8e-23 81.8 0.0 1.3e-17 64.5 0.1 2.4 2 0 0 2 2 2 2 Methylmalonic aciduria and homocystinuria type D protein Ank_2 PF12796.7 RLN93891.1 - 0.0019 18.8 0.0 0.007 16.9 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 RLN93891.1 - 0.0049 17.3 0.0 0.022 15.2 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 RLN93891.1 - 0.013 16.0 0.0 0.048 14.2 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN93891.1 - 0.02 15.4 0.0 0.15 12.7 0.0 2.6 1 0 0 1 1 1 0 Ankyrin repeat Sel1 PF08238.12 RLN93893.1 - 2.7e-40 135.9 19.6 2.3e-08 34.5 0.5 6.3 6 0 0 6 6 6 6 Sel1 repeat TPR_14 PF13428.6 RLN93893.1 - 0.0075 17.0 10.1 37 5.5 0.1 5.8 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 RLN93893.1 - 0.32 11.7 16.8 31 5.5 0.1 6.3 6 1 0 6 6 6 0 Tetratricopeptide repeat Cys_Met_Meta_PP PF01053.20 RLN93894.1 - 1.7e-81 273.7 0.1 1.6e-49 168.5 0.0 2.0 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme ABC1 PF03109.16 RLN93895.1 - 8.4e-23 80.8 0.0 1.6e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 RLN93895.1 - 4.7e-08 32.7 0.0 0.0033 16.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 RLN93895.1 - 6e-05 23.1 0.1 6e-05 23.1 0.1 3.1 2 2 1 3 3 3 1 Phosphotransferase enzyme family Lyase_1 PF00206.20 RLN93896.1 - 5.6e-67 226.4 0.0 8.3e-67 225.8 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 RLN93896.1 - 1.4e-23 83.4 0.2 3.1e-23 82.3 0.2 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Ribosomal_S21 PF01165.20 RLN93897.1 - 4.2e-08 32.8 0.4 7e-08 32.1 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 Flavi_capsid PF01003.19 RLN93897.1 - 0.027 14.2 3.5 0.038 13.8 3.4 1.3 1 1 0 1 1 1 0 Flavivirus capsid protein C Picorna_P3A PF06363.11 RLN93897.1 - 0.057 13.3 0.1 0.07 13.0 0.1 1.3 1 1 0 1 1 1 0 Picornaviridae P3A protein ArsA_ATPase PF02374.15 RLN93898.1 - 7e-38 130.5 0.0 8.1e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.23 RLN93898.1 - 6.4e-11 42.4 0.0 7.3e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 RLN93898.1 - 1.2e-10 41.5 0.0 1.4e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 RLN93898.1 - 2e-06 27.5 0.0 2.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 RLN93898.1 - 0.00025 20.6 0.3 0.00031 20.3 0.3 1.4 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 RLN93898.1 - 0.00033 20.2 0.0 0.00042 19.9 0.0 1.2 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 RLN93898.1 - 0.0015 18.2 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain NB-ARC PF00931.22 RLN93898.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.16 RLN93898.1 - 0.021 14.3 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein MeaB PF03308.16 RLN93898.1 - 0.024 13.7 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 RLN93898.1 - 0.1 12.2 0.2 0.16 11.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 RLN93898.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 RLN93898.1 - 0.18 11.1 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Glyco_hydro81C PF17652.1 RLN93899.1 - 8.6e-62 209.4 0.0 1.7e-48 165.7 0.2 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 RLN93899.1 - 4e-33 115.0 0.2 5.7e-18 65.2 0.2 2.4 2 1 0 2 2 2 2 Glycosyl hydrolase family 81 N-terminal domain AA_permease_2 PF13520.6 RLN93900.1 - 1e-24 87.2 33.3 1.4e-24 86.7 33.3 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN93900.1 - 1.2e-12 47.2 22.3 1.7e-09 36.8 8.5 2.1 2 0 0 2 2 2 2 Amino acid permease PalH PF08733.10 RLN93900.1 - 0.035 13.1 1.1 1.9 7.4 1.6 2.2 1 1 1 2 2 2 0 PalH/RIM21 VPS13_C PF16909.5 RLN93901.1 - 2.2e-22 79.7 3.6 3.5e-20 72.5 0.4 2.7 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal C2 PF00168.30 RLN93901.1 - 2.4e-17 63.1 0.0 4.8e-12 46.1 0.0 2.8 2 0 0 2 2 2 2 C2 domain SHR-BD PF06650.12 RLN93901.1 - 1.6e-16 60.5 0.1 8.6e-16 58.1 0.0 2.4 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 EF-hand_1 PF00036.32 RLN93901.1 - 3.1e-12 45.1 0.9 3.3e-05 23.1 0.8 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RLN93901.1 - 2.4e-11 43.9 1.2 8.2e-11 42.2 1.2 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN93901.1 - 5.4e-11 41.5 1.8 0.00013 21.6 0.4 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RLN93901.1 - 3.6e-08 32.5 0.4 0.012 15.1 0.2 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RLN93901.1 - 1.3e-05 25.0 0.4 0.049 13.5 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain pair NUDIX PF00293.28 RLN93902.1 - 2.3e-09 37.4 0.2 3.4e-09 36.8 0.2 1.2 1 0 0 1 1 1 1 NUDIX domain Pkinase_Tyr PF07714.17 RLN93903.1 - 5.5e-51 173.3 0.0 1.7e-36 125.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN93903.1 - 2.3e-45 155.0 0.0 5.5e-33 114.4 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Arm PF00514.23 RLN93903.1 - 3.8e-19 68.0 8.1 0.00011 22.1 0.1 7.5 8 0 0 8 8 8 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN93903.1 - 9.7e-06 25.9 16.6 0.013 15.9 0.2 5.0 4 1 1 5 5 5 3 HEAT repeats HEAT_EZ PF13513.6 RLN93903.1 - 9.1e-05 22.9 10.4 0.003 18.0 1.1 4.4 4 0 0 4 4 4 2 HEAT-like repeat Kinase-like PF14531.6 RLN93903.1 - 0.014 14.7 0.0 1.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Kinase-like NAGidase PF07555.13 RLN93903.1 - 0.026 13.9 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase Pkinase_fungal PF17667.1 RLN93903.1 - 0.026 13.3 0.0 0.049 12.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase HEAT PF02985.22 RLN93903.1 - 0.26 11.6 5.2 4.9 7.7 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat cNMP_binding PF00027.29 RLN93904.1 - 1.8e-18 66.4 1.8 6e-05 23.0 0.0 4.0 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain MAT1 PF06391.13 RLN93904.1 - 2.3 8.0 10.1 8.6 6.1 1.7 2.4 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF812 PF05667.11 RLN93904.1 - 3.4 6.4 13.3 1.6 7.5 3.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF812) HLH PF00010.26 RLN93905.1 - 1.9e-07 30.9 1.0 2.1e-06 27.6 0.2 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HALZ PF02183.18 RLN93905.1 - 0.0075 16.5 0.5 0.013 15.7 0.5 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper EspB_PE PF18625.1 RLN93905.1 - 0.18 12.3 0.8 0.52 10.8 0.1 2.0 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain EF-hand_6 PF13405.6 RLN93906.1 - 4e-10 38.8 0.0 0.0003 20.5 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RLN93906.1 - 5.3e-10 38.1 0.0 0.00021 20.6 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RLN93906.1 - 1e-09 38.7 0.1 1.9e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN93906.1 - 6.5e-06 25.4 0.0 0.042 13.4 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RLN93906.1 - 7.1e-05 22.6 0.1 0.0003 20.6 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain pair YqaJ PF09588.10 RLN93906.1 - 0.0024 18.0 0.0 0.089 12.9 0.0 2.4 2 0 0 2 2 2 1 YqaJ-like viral recombinase domain FlgN PF05130.12 RLN93906.1 - 0.64 10.5 6.2 23 5.5 0.0 2.7 3 0 0 3 3 3 0 FlgN protein FACT-Spt16_Nlob PF14826.6 RLN93907.1 - 2e-42 144.7 0.1 1.7e-41 141.7 0.1 2.6 1 1 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 RLN93907.1 - 9.6e-33 113.6 0.0 1.5e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 SPT16 PF08644.11 RLN93907.1 - 5.2e-32 111.1 0.1 5.2e-32 111.1 0.1 2.2 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) DUF2407_C PF13373.6 RLN93907.1 - 2.9 8.1 9.0 17 5.6 2.0 3.1 3 0 0 3 3 3 0 DUF2407 C-terminal domain DUF1682 PF07946.14 RLN93907.1 - 5.2 6.2 9.5 8.6 5.5 9.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Myb_DNA-binding PF00249.31 RLN93909.1 - 3.7e-09 36.6 0.0 7.7e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN93909.1 - 0.073 13.3 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain ABATE PF07336.11 RLN93909.1 - 0.45 11.2 3.0 0.71 10.6 3.0 1.6 1 1 0 1 1 1 0 Putative stress-induced transcription regulator Myb_DNA-binding PF00249.31 RLN93910.1 - 1.2e-09 38.2 0.0 2.3e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Patatin PF01734.22 RLN93911.1 - 2.2e-10 41.1 1.3 7e-08 32.9 0.3 2.4 2 1 0 2 2 2 1 Patatin-like phospholipase RRM_1 PF00076.22 RLN93912.1 - 1.8e-81 267.9 0.0 2.8e-20 71.9 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 RLN93912.1 - 1.2e-29 102.3 1.5 8.5e-29 99.5 0.8 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.6 RLN93912.1 - 1.6e-05 24.8 0.1 0.68 10.0 0.0 4.2 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 RLN93912.1 - 3.6e-05 23.7 0.0 3.3 7.7 0.0 3.9 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 RLN93912.1 - 0.0001 22.3 0.0 10 6.3 0.0 4.0 4 1 0 4 4 4 2 RNA recognition motif SET_assoc PF11767.8 RLN93912.1 - 0.019 14.6 0.1 17 5.2 0.0 3.3 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated RNA_bind PF08675.11 RLN93912.1 - 0.022 14.8 0.1 0.28 11.2 0.0 2.7 3 0 0 3 3 3 0 RNA binding domain RGP PF03214.13 RLN93912.1 - 0.083 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide OB_RNB PF08206.11 RLN93912.1 - 0.46 10.2 1.6 33 4.2 0.1 3.2 3 0 0 3 3 3 0 Ribonuclease B OB domain Asparaginase_2 PF01112.18 RLN93914.1 - 3e-46 157.9 0.0 6.5e-46 156.8 0.0 1.6 1 0 0 1 1 1 1 Asparaginase zf-BED PF02892.15 RLN93915.1 - 0.016 15.2 0.1 0.033 14.2 0.1 1.5 1 0 0 1 1 1 0 BED zinc finger YopH_N PF09013.10 RLN93915.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 YopH, N-terminal Cellulase PF00150.18 RLN93916.1 - 2.1e-42 145.5 0.0 2.7e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1398 PF07166.11 RLN93916.1 - 0.22 11.6 0.1 0.4 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) DUF1336 PF07059.12 RLN93917.1 - 2.7e-71 240.3 0.0 3.6e-71 239.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) START PF01852.19 RLN93917.1 - 5.4e-05 22.7 0.3 0.061 12.7 0.0 2.2 1 1 1 2 2 2 2 START domain Mucin PF01456.17 RLN93917.1 - 1.1 9.3 15.5 0.045 13.7 8.8 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3439 PF11921.8 RLN93917.1 - 1.7 8.7 8.5 2.7 8.0 7.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Peptidase_M16_C PF05193.21 RLN93918.1 - 2e-09 37.7 0.0 3.5e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16_M PF16187.5 RLN93918.1 - 0.0014 17.9 0.1 0.0023 17.3 0.1 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Pkinase_Tyr PF07714.17 RLN93919.1 - 3.5e-15 56.0 0.0 4.5e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN93919.1 - 4.7e-13 49.1 0.0 6.2e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TMEM154 PF15102.6 RLN93919.1 - 0.021 14.7 0.3 0.043 13.7 0.1 1.4 1 1 0 1 1 1 0 TMEM154 protein family Trp_oprn_chp PF09534.10 RLN93919.1 - 0.025 14.4 0.1 0.025 14.4 0.1 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1180 PF06679.12 RLN93919.1 - 0.041 14.3 0.8 0.076 13.4 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) BatD PF13584.6 RLN93919.1 - 0.046 12.5 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance Peptidase_M56 PF05569.11 RLN93919.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 Podoplanin PF05808.11 RLN93919.1 - 0.22 11.6 7.2 0.59 10.2 7.2 1.8 1 1 0 1 1 1 0 Podoplanin RIFIN PF02009.16 RLN93919.1 - 0.25 11.2 0.1 0.35 10.7 0.1 1.2 1 0 0 1 1 1 0 Rifin Pkinase PF00069.25 RLN93920.1 - 1.1e-36 126.6 0.0 1.3e-36 126.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN93920.1 - 2.7e-29 102.3 0.0 3.6e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RLN93920.1 - 0.079 11.9 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_Tyr PF07714.17 RLN93921.1 - 2.2e-39 135.3 0.0 3.5e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN93921.1 - 3.7e-37 128.1 0.0 5.8e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.23 RLN93921.1 - 1.8e-14 53.2 8.6 0.23 11.6 0.0 7.1 7 0 0 7 7 7 5 Armadillo/beta-catenin-like repeat Ank_2 PF12796.7 RLN93921.1 - 7.7e-09 36.0 0.1 7.2e-08 32.9 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN93921.1 - 2.6e-08 33.9 0.0 9.7e-08 32.1 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Atx10homo_assoc PF09759.9 RLN93921.1 - 9.5e-05 22.4 0.0 1.3 9.1 0.0 3.6 3 0 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain Ank_4 PF13637.6 RLN93921.1 - 0.0017 18.9 0.0 0.0064 17.0 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 RLN93921.1 - 0.007 16.8 0.0 0.055 13.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat HEAT PF02985.22 RLN93921.1 - 0.011 16.0 0.7 82 3.9 0.0 4.9 4 0 0 4 4 4 0 HEAT repeat Kinase-like PF14531.6 RLN93921.1 - 0.021 14.2 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SRA1 PF07304.11 RLN93921.1 - 0.082 12.7 0.2 0.21 11.4 0.2 1.6 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) FCD PF07729.12 RLN93921.1 - 0.12 12.7 0.5 0.78 10.2 0.0 2.6 2 1 1 3 3 3 0 FCD domain HEAT_EZ PF13513.6 RLN93921.1 - 0.6 10.7 2.9 12 6.5 0.1 3.8 2 1 2 4 4 4 0 HEAT-like repeat HEAT_2 PF13646.6 RLN93921.1 - 3 8.3 15.0 3.5 8.1 2.1 4.5 2 1 3 5 5 5 0 HEAT repeats Trypsin_2 PF13365.6 RLN93922.1 - 4e-16 60.2 0.7 9.5e-16 59.0 0.7 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 RLN93922.1 - 8.2e-07 29.0 3.6 2.4e-06 27.6 3.6 1.8 1 1 0 1 1 1 1 Trypsin Peptidase_C3 PF00548.20 RLN93922.1 - 0.00047 20.1 0.0 0.00096 19.1 0.0 1.5 1 0 0 1 1 1 1 3C cysteine protease (picornain 3C) TFIIE-A_C PF11521.8 RLN93922.1 - 0.33 11.3 1.3 0.85 10.0 0.2 2.1 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha DUF3403 PF11883.8 RLN93922.1 - 0.64 10.2 2.4 1.9 8.7 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) UCH PF00443.29 RLN93923.1 - 1.2e-41 142.9 0.0 1.8e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN93923.1 - 1.7e-17 64.0 0.0 2.9e-15 56.7 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 RLN93923.1 - 1.3e-06 28.6 0.4 3.4e-05 24.1 0.1 3.0 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein WD40 PF00400.32 RLN93923.1 - 1.5e-06 28.8 13.7 0.08 13.8 0.1 6.9 7 0 0 7 7 7 2 WD domain, G-beta repeat zf-ISL3 PF14690.6 RLN93923.1 - 0.17 12.5 1.2 0.4 11.4 0.2 2.3 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Peptidase_C98 PF15499.6 RLN93923.1 - 0.35 10.3 3.4 7.5 5.9 0.1 2.7 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Trypsin PF00089.26 RLN93924.1 - 0.01 15.7 1.1 0.017 15.0 0.4 1.7 2 0 0 2 2 2 0 Trypsin Trypsin_2 PF13365.6 RLN93924.1 - 0.028 15.3 0.0 0.053 14.4 0.0 1.6 1 0 0 1 1 1 0 Trypsin-like peptidase domain Methyltransf_11 PF08241.12 RLN93925.1 - 5.7e-15 55.7 0.0 1.6e-14 54.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN93925.1 - 6.1e-15 55.7 0.1 2e-14 54.0 0.0 1.9 2 1 1 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN93925.1 - 2.4e-13 50.0 0.0 4.5e-13 49.1 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 RLN93925.1 - 6.4e-10 39.7 0.0 1.5e-09 38.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN93925.1 - 1.3e-09 38.0 0.0 2.5e-09 37.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN93925.1 - 3.3e-08 33.5 0.0 8.2e-08 32.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 RLN93925.1 - 0.0049 16.4 0.0 0.023 14.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 RLN93925.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 RLN93926.1 - 4.1e-15 56.3 0.0 1.1e-14 54.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN93926.1 - 4.7e-15 56.0 0.0 1.1e-14 54.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN93926.1 - 2.1e-13 50.1 0.0 1.4e-12 47.4 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 RLN93926.1 - 3.6e-11 43.1 0.0 6e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN93926.1 - 1.3e-10 41.9 0.0 2.7e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN93926.1 - 6.8e-09 35.8 0.0 1.8e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN93926.1 - 0.011 15.2 0.0 0.062 12.8 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain CTNNBL PF08216.11 RLN93927.1 - 6.8e-25 87.2 0.0 2.1e-24 85.7 0.0 1.9 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear DUF3446 PF11928.8 RLN93927.1 - 0.069 13.5 4.4 0.12 12.7 0.4 2.8 3 0 0 3 3 3 0 Early growth response N-terminal domain Ydc2-catalyt PF09159.10 RLN93927.1 - 0.64 9.7 3.8 2.1 8.0 0.1 2.9 3 0 0 3 3 3 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 PT-VENN PF04829.13 RLN93927.1 - 1.6 8.8 7.3 0.079 13.0 0.9 2.1 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif LPP PF04728.13 RLN93929.1 - 0.014 15.8 7.2 0.098 13.1 0.1 3.7 4 1 0 4 4 4 0 Lipoprotein leucine-zipper DUF2730 PF10805.8 RLN93929.1 - 0.1 12.7 2.3 2.7 8.1 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) NPR3 PF03666.13 RLN93931.1 - 2.3e-43 148.7 0.0 2.4e-24 86.0 1.2 3.8 1 1 1 3 3 3 3 Nitrogen Permease regulator of amino acid transport activity 3 Antimicrobial19 PF08225.11 RLN93931.1 - 0.026 14.1 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 Pseudin antimicrobial peptide DUF2048 PF09752.9 RLN93932.1 - 9.6e-38 130.2 0.0 4.7e-23 81.8 0.0 2.1 1 1 1 2 2 2 2 Abhydrolase domain containing 18 Abhydrolase_1 PF00561.20 RLN93932.1 - 1.2e-05 25.1 0.2 4.2e-05 23.3 0.1 2.0 2 1 1 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN93932.1 - 0.02 14.2 0.2 0.17 11.1 0.2 2.2 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Lipase_GDSL_2 PF13472.6 RLN93932.1 - 0.084 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Esterase PF00756.20 RLN93932.1 - 0.15 11.7 1.5 0.25 10.9 1.5 1.6 1 1 0 1 1 1 0 Putative esterase ABC_tran PF00005.27 RLN93933.1 - 6.4e-06 26.7 0.2 1.1e-05 26.0 0.2 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 RLN93933.1 - 0.0039 16.9 0.9 0.0062 16.3 0.9 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN93933.1 - 0.0086 16.5 0.3 0.015 15.7 0.1 1.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RLN93933.1 - 0.0097 16.2 0.0 0.021 15.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RLN93933.1 - 0.01 15.2 0.3 0.02 14.2 0.1 1.6 2 0 0 2 2 2 0 Zeta toxin DUF3987 PF13148.6 RLN93933.1 - 0.021 13.9 0.3 0.048 12.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Ploopntkinase3 PF18751.1 RLN93933.1 - 0.029 14.3 0.1 0.048 13.6 0.1 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 RsgA_GTPase PF03193.16 RLN93933.1 - 0.043 13.7 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 RLN93933.1 - 0.088 12.4 0.2 0.18 11.4 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 RLN93933.1 - 0.1 12.6 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 RLN93933.1 - 0.16 12.4 0.1 0.43 11.0 0.2 1.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 RLN93933.1 - 0.18 11.1 0.4 1.2 8.4 0.2 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.12 RLN93933.1 - 0.18 11.7 0.2 0.33 10.9 0.2 1.4 1 0 0 1 1 1 0 NACHT domain DUF87 PF01935.17 RLN93933.1 - 0.19 11.8 0.0 0.3 11.1 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_10 PF12846.7 RLN93933.1 - 0.2 10.5 0.1 0.29 10.0 0.1 1.2 1 0 0 1 1 1 0 AAA-like domain DUF2075 PF09848.9 RLN93933.1 - 0.25 10.5 0.0 1.9 7.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DHDPS PF00701.22 RLN93934.1 - 1.5e-78 263.5 0.0 2e-78 263.0 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family LMBR1 PF04791.16 RLN93935.1 - 4.5e-66 223.8 0.4 5.1e-66 223.6 0.4 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Methyltransf_25 PF13649.6 RLN93936.1 - 2.9e-15 56.8 0.0 5.1e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN93936.1 - 6.4e-15 55.6 0.0 1.3e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN93936.1 - 5.9e-14 52.0 0.0 6.9e-13 48.5 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 RLN93936.1 - 1.8e-11 44.7 0.0 2.9e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN93936.1 - 7.7e-09 35.5 0.0 1.3e-08 34.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN93936.1 - 1.1e-07 31.8 0.0 2.1e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 RLN93936.1 - 0.014 14.9 0.0 0.034 13.6 0.0 1.7 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.6 RLN93936.1 - 0.038 14.0 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 RLN93936.1 - 0.058 12.9 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_18 PF12847.7 RLN93936.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain bPH_6 PF10756.9 RLN93936.1 - 0.19 11.9 2.4 4.7 7.4 0.1 2.9 2 1 1 3 3 3 0 Bacterial PH domain Pkinase_Tyr PF07714.17 RLN93937.1 - 7.4e-44 150.0 0.0 1.2e-43 149.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN93937.1 - 1.5e-43 149.1 0.0 2.2e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 RLN93937.1 - 0.066 12.6 0.2 0.14 11.5 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OrfB_Zn_ribbon PF07282.11 RLN93938.1 - 1e-05 25.4 6.0 0.018 15.0 0.3 3.4 3 0 0 3 3 3 2 Putative transposase DNA-binding domain DUF4666 PF15697.5 RLN93939.1 - 0.043 14.5 1.0 0.043 14.5 1.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4666) Oxidored_nitro PF00148.19 RLN93939.1 - 0.079 11.7 1.0 3.1 6.4 0.1 2.8 2 1 0 3 3 3 0 Nitrogenase component 1 type Oxidoreductase PX PF00787.24 RLN93940.1 - 2.3e-15 56.6 0.0 1.6e-14 53.9 0.0 2.4 3 0 0 3 3 3 1 PX domain ZZ PF00569.17 RLN93941.1 - 4.6e-11 42.3 0.6 1.4e-10 40.8 0.8 1.6 2 0 0 2 2 2 1 Zinc finger, ZZ type Ank_5 PF13857.6 RLN93941.1 - 0.00013 22.2 0.0 0.0015 18.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Cnd2 PF05786.14 RLN93943.1 - 5.1 5.6 9.6 5.7 5.5 9.6 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 Hist_deacetyl PF00850.19 RLN93944.1 - 9.4e-12 45.0 0.1 1e-11 44.9 0.1 1.0 1 0 0 1 1 1 1 Histone deacetylase domain DUF4658 PF15555.6 RLN93945.1 - 0.099 12.8 0.6 0.33 11.1 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) PTS_2-RNA PF01885.16 RLN93947.1 - 2.4e-63 213.4 0.0 3e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Pkinase PF00069.25 RLN93948.1 - 2.6e-123 410.6 0.0 1.8e-64 217.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN93948.1 - 4.1e-47 160.7 0.0 3.2e-22 79.1 0.0 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase WW PF00397.26 RLN93948.1 - 3e-15 56.0 0.6 4.5e-07 29.9 0.1 2.5 2 0 0 2 2 2 2 WW domain Haspin_kinase PF12330.8 RLN93948.1 - 1.9e-08 33.6 0.0 0.0018 17.3 0.0 2.8 2 1 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 RLN93948.1 - 1.3e-07 31.8 0.5 0.016 15.2 0.1 3.0 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 RLN93948.1 - 3.4e-05 23.3 0.9 0.12 11.7 0.2 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN93948.1 - 6.5e-05 22.4 0.0 0.38 10.0 0.0 2.9 2 0 0 2 2 2 2 Kinase-like Choline_kinase PF01633.20 RLN93948.1 - 0.029 13.9 0.0 10 5.6 0.0 2.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase PI3K_1B_p101 PF10486.9 RLN93948.1 - 8.9 3.9 10.2 16 3.1 10.2 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Dcc1 PF09724.9 RLN93949.1 - 9.6e-84 281.5 0.2 2.2e-83 280.3 0.1 1.7 2 0 0 2 2 2 1 Sister chromatid cohesion protein Dcc1 Pkinase_Tyr PF07714.17 RLN93950.1 - 2.7e-79 266.1 0.0 1.3e-40 139.4 0.0 3.3 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 RLN93950.1 - 2.7e-76 256.4 0.0 5.5e-39 134.1 0.0 3.8 4 0 0 4 4 4 2 Protein kinase domain Pkinase_fungal PF17667.1 RLN93950.1 - 9.2e-05 21.4 0.0 0.18 10.6 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Kdo PF06293.14 RLN93950.1 - 0.00095 18.6 0.0 0.97 8.7 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN93950.1 - 0.0026 17.1 0.0 0.046 13.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 RLN93950.1 - 0.0053 16.4 0.0 1.9 8.1 0.0 2.6 2 0 0 2 2 2 2 RIO1 family APH PF01636.23 RLN93950.1 - 0.41 10.5 12.0 1.9 8.4 0.0 4.4 5 0 0 5 5 5 0 Phosphotransferase enzyme family Mito_carr PF00153.27 RLN93951.1 - 2.7e-36 123.4 2.0 2.8e-22 78.4 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein ECH_1 PF00378.20 RLN93952.1 - 1.1e-47 162.5 0.1 2.6e-47 161.3 0.1 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RLN93952.1 - 2e-26 93.3 0.1 2e-23 83.5 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase APO_RNA-bind PF05634.11 RLN93952.1 - 0.099 12.0 0.2 0.28 10.5 0.1 1.6 2 0 0 2 2 2 0 APO RNA-binding CCDC53 PF10152.9 RLN93953.1 - 0.0015 19.0 2.4 0.0015 19.0 2.4 2.6 3 1 0 3 3 3 1 Subunit CCDC53 of WASH complex CP12 PF02672.15 RLN93953.1 - 0.035 14.9 6.3 4 8.3 0.0 3.3 2 0 0 2 2 2 0 CP12 domain DUF4300 PF14133.6 RLN93953.1 - 0.049 13.3 0.1 0.049 13.3 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4300) WH2 PF02205.20 RLN93953.1 - 0.41 10.5 14.1 5.5 7.0 0.2 4.9 5 0 0 5 5 5 0 WH2 motif Sas10_Utp3 PF04000.15 RLN93954.1 - 0.073 13.7 0.4 0.19 12.4 0.4 1.8 1 0 0 1 1 1 0 Sas10/Utp3/C1D family DUF4570 PF15134.6 RLN93954.1 - 3.7 7.6 6.9 0.81 9.7 1.5 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4570) Macoilin PF09726.9 RLN93954.1 - 5.5 5.4 9.9 7.8 4.9 9.9 1.2 1 0 0 1 1 1 0 Macoilin family MukF_M PF17192.4 RLN93955.1 - 0.12 12.2 3.4 0.35 10.6 3.4 1.9 1 0 0 1 1 1 0 MukF middle domain DUF4570 PF15134.6 RLN93958.1 - 0.035 14.1 0.1 0.058 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) Herpes_UL56 PF04534.12 RLN93959.1 - 0.34 10.4 9.2 0.33 10.4 1.1 2.3 2 0 0 2 2 2 0 Herpesvirus UL56 protein EIIA-man PF03610.16 RLN93959.1 - 0.42 10.9 1.4 19 5.5 0.0 3.5 4 0 0 4 4 4 0 PTS system fructose IIA component DivIC PF04977.15 RLN93960.1 - 0.047 13.5 0.7 0.13 12.1 0.7 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF4337 PF14235.6 RLN93960.1 - 0.094 12.8 1.3 0.12 12.4 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) SAGA-Tad1 PF12767.7 RLN93961.1 - 0.022 14.5 10.0 0.033 13.9 2.9 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Helo_like_N PF17111.5 RLN93961.1 - 0.57 9.5 3.5 0.28 10.5 0.2 2.0 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins CCDC53 PF10152.9 RLN93961.1 - 5.9 7.3 13.3 8.4 6.8 1.2 2.7 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex TPR_2 PF07719.17 RLN93962.1 - 2.5e-43 142.7 17.5 0.00015 21.6 1.1 14.0 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_1 PF00515.28 RLN93962.1 - 1.9e-33 112.9 27.0 0.00051 19.8 0.0 13.3 15 0 0 15 15 14 8 Tetratricopeptide repeat TPR_19 PF14559.6 RLN93962.1 - 1.7e-31 108.5 10.0 1.7e-06 28.5 0.0 9.4 5 3 6 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.6 RLN93962.1 - 9.1e-29 99.8 0.9 3.1e-07 30.9 0.2 8.9 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 RLN93962.1 - 4.7e-26 88.8 14.4 0.0036 17.4 0.0 11.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 RLN93962.1 - 7.7e-25 85.1 9.3 0.001 19.0 0.0 11.0 12 0 0 12 12 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 RLN93962.1 - 1.4e-23 81.6 8.3 0.012 16.4 0.0 10.2 8 2 3 11 11 9 5 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN93962.1 - 3.3e-21 75.3 12.8 6e-06 26.4 2.4 6.9 5 1 1 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 RLN93962.1 - 1.7e-19 69.2 10.8 0.005 16.5 0.6 11.1 9 1 2 11 11 11 5 TPR repeat TPR_6 PF13174.6 RLN93962.1 - 6.4e-19 67.3 29.8 0.0037 17.8 0.0 12.3 15 0 0 15 15 12 5 Tetratricopeptide repeat TPR_12 PF13424.6 RLN93962.1 - 4.8e-18 65.2 26.1 0.00056 20.1 0.1 10.0 8 4 3 11 11 10 6 Tetratricopeptide repeat TPR_17 PF13431.6 RLN93962.1 - 9.7e-16 56.9 17.6 0.56 10.7 0.0 12.7 14 0 0 14 14 13 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN93962.1 - 1.1e-12 47.4 17.6 0.15 12.0 0.0 9.7 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_9 PF13371.6 RLN93962.1 - 1.4e-07 31.6 5.3 0.64 10.2 0.0 6.9 6 3 2 8 8 8 2 Tetratricopeptide repeat YfiO PF13525.6 RLN93962.1 - 3.4e-07 30.2 4.5 0.13 12.0 0.3 4.7 4 0 0 4 4 4 2 Outer membrane lipoprotein TPR_4 PF07721.14 RLN93962.1 - 1.3e-05 25.3 0.1 3.6 8.5 0.0 6.3 7 0 0 7 7 5 1 Tetratricopeptide repeat ChAPs PF09295.10 RLN93962.1 - 0.0018 17.3 0.2 2.9 6.8 0.0 3.9 2 1 1 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) NARP1 PF12569.8 RLN93962.1 - 0.011 14.6 0.2 0.011 14.6 0.2 5.8 3 3 2 6 6 4 0 NMDA receptor-regulated protein 1 DUF4810 PF16068.5 RLN93962.1 - 0.012 16.2 6.9 3.4 8.3 0.0 6.0 5 1 1 6 6 5 0 Domain of unknown function (DUF4810) MIT PF04212.18 RLN93962.1 - 0.044 13.9 19.5 1.7 8.8 0.0 6.1 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 RLN93962.1 - 0.49 10.5 23.2 2.8 8.1 1.0 6.4 5 1 1 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat SRP_TPR_like PF17004.5 RLN93962.1 - 1.1 9.3 12.6 2.3 8.3 0.8 4.7 5 1 0 5 5 4 0 Putative TPR-like repeat TPR_3 PF07720.12 RLN93962.1 - 4.6 7.3 20.1 17 5.5 0.8 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat PX PF00787.24 RLN93964.1 - 2e-09 37.4 0.0 3.9e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 PX domain DUF4611 PF15387.6 RLN93964.1 - 2.3 8.5 6.3 22 5.3 1.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Ribonuc_red_sm PF00268.21 RLN93965.1 - 2.5e-116 388.0 0.3 3e-116 387.8 0.3 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Bac_surface_Ag PF01103.23 RLN93966.1 - 9.1e-32 110.8 0.1 3.9e-22 79.2 0.1 2.2 2 0 0 2 2 2 2 Surface antigen ATP-synt_C PF00137.21 RLN93967.1 - 7.1e-14 51.9 11.7 1e-13 51.4 11.7 1.2 1 0 0 1 1 1 1 ATP synthase subunit C DUF1869 PF08956.10 RLN93967.1 - 0.091 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) DUF819 PF05684.12 RLN93967.1 - 0.26 10.3 6.3 0.29 10.1 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF819) ChaC PF04752.12 RLN93968.1 - 4.4e-54 183.2 0.0 5e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 RLN93968.1 - 7.2e-06 26.6 0.2 1.7e-05 25.4 0.2 1.7 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 RLN93968.1 - 0.0003 21.1 0.0 0.00049 20.5 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family DSPc PF00782.20 RLN93968.1 - 0.065 13.0 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Mce4_CUP1 PF11887.8 RLN93969.1 - 0.032 13.7 1.1 0.08 12.4 0.9 1.7 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative CHASE7 PF17151.4 RLN93969.1 - 2.6 7.6 15.9 0.27 10.8 10.5 1.8 1 1 1 2 2 2 0 Periplasmic sensor domain Vac14_Fab1_bd PF12755.7 RLN93970.1 - 2.9e-07 31.0 0.0 0.078 13.6 0.0 3.8 3 1 0 3 3 3 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 RLN93970.1 - 1.8e-06 28.1 0.6 0.02 15.0 0.0 4.5 2 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RLN93970.1 - 1.8e-06 27.7 18.2 0.27 11.6 0.0 8.2 8 1 1 9 9 9 2 HEAT repeat HEAT_2 PF13646.6 RLN93970.1 - 4.6e-05 23.7 14.0 0.84 10.1 5.3 5.1 3 2 2 5 5 5 4 HEAT repeats Sec7_N PF12783.7 RLN93970.1 - 0.0046 16.9 0.2 0.028 14.3 0.0 2.4 3 1 1 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_EZ PF13513.6 RLN93970.1 - 0.015 15.8 16.2 0.085 13.4 0.1 6.2 4 3 4 8 8 8 0 HEAT-like repeat Dopey_N PF04118.14 RLN93970.1 - 0.019 14.1 0.2 1.9 7.5 0.0 2.8 3 0 0 3 3 3 0 Dopey, N-terminal PerC PF06069.11 RLN93970.1 - 0.12 12.7 1.1 0.24 11.6 1.1 1.5 1 0 0 1 1 1 0 PerC transcriptional activator PRA1 PF03208.19 RLN93971.1 - 0.0022 17.6 0.1 0.0036 16.9 0.1 1.3 1 0 0 1 1 1 1 PRA1 family protein LRR_6 PF13516.6 RLN93972.1 - 1.9e-06 27.4 9.9 0.06 13.4 0.0 5.1 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.7 RLN93972.1 - 0.0036 17.7 2.3 0.45 11.0 0.2 3.2 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN93972.1 - 0.0039 17.5 1.4 10 7.1 0.0 3.8 4 0 0 4 4 4 2 Leucine Rich Repeat GTP_EFTU PF00009.27 RLN93973.1 - 2.8e-52 177.1 0.2 4.4e-52 176.4 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 RLN93973.1 - 1.4e-21 76.3 0.0 3.5e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 RLN93973.1 - 1.7e-07 31.3 0.2 4.1e-07 30.1 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RLN93973.1 - 0.00018 21.5 0.1 0.047 13.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 RLN93973.1 - 0.0029 17.1 0.1 0.0073 15.8 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Septin PF00735.18 RLN93973.1 - 0.0037 16.6 0.1 0.0061 15.9 0.1 1.2 1 0 0 1 1 1 1 Septin FeoB_N PF02421.18 RLN93973.1 - 0.0039 16.7 0.3 0.039 13.5 0.3 2.6 1 1 0 1 1 1 1 Ferrous iron transport protein B EFG_II PF14492.6 RLN93973.1 - 0.0049 16.9 0.1 0.023 14.8 0.0 2.1 1 1 1 2 2 2 1 Elongation Factor G, domain II Roc PF08477.13 RLN93973.1 - 0.071 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN93973.1 - 0.11 11.9 0.0 0.34 10.3 0.0 1.6 1 1 0 1 1 1 0 ADP-ribosylation factor family Glucan_synthase PF02364.15 RLN93974.1 - 2.1e-145 486.0 9.7 9.9e-127 424.3 0.2 2.5 2 1 1 3 3 3 2 1,3-beta-glucan synthase component SKN1 PF03935.15 RLN93974.1 - 2.4e-73 247.3 1.5 4e-73 246.5 1.5 1.3 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) FKS1_dom1 PF14288.6 RLN93974.1 - 2.1e-20 73.4 3.1 2.4e-19 70.0 3.1 2.4 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF4203 PF13886.6 RLN93974.1 - 1.2e-06 28.3 20.0 1.2e-06 28.3 20.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) DUF21 PF01595.20 RLN93975.1 - 3.1e-12 46.6 1.5 4.5e-12 46.0 1.5 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain GNAT_acetyltr_2 PF13718.6 RLN93976.1 - 2.9e-98 327.8 0.0 5.9e-98 326.8 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 RLN93976.1 - 3.5e-62 209.4 0.1 8e-62 208.2 0.1 1.7 2 0 0 2 2 2 1 Helicase tRNA_bind_2 PF13725.6 RLN93976.1 - 3.9e-52 177.3 0.2 3.9e-52 177.3 0.2 1.9 2 0 0 2 2 2 1 Possible tRNA binding domain DUF1726 PF08351.11 RLN93976.1 - 2e-33 114.2 0.1 4.4e-33 113.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 RLN93976.1 - 0.0013 19.0 0.0 0.23 11.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_pol_Rpb2_1 PF04563.15 RLN93978.1 - 0.00037 20.1 0.1 0.00049 19.7 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit CH PF00307.31 RLN93979.1 - 4e-09 36.6 0.0 8.7e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain bZIP_1 PF00170.21 RLN93979.1 - 0.014 15.5 0.6 0.014 15.5 0.6 3.9 2 1 2 4 4 4 0 bZIP transcription factor WD40_alt PF14077.6 RLN93979.1 - 0.095 12.6 0.7 0.36 10.7 0.7 2.0 1 0 0 1 1 1 0 Alternative WD40 repeat motif Tetraspanin PF00335.20 RLN93981.1 - 1.3e-17 64.3 27.5 6.6e-10 39.1 5.1 2.7 2 1 1 3 3 3 2 Tetraspanin family DUF872 PF05915.12 RLN93981.1 - 1 9.5 12.0 2.7 8.2 3.4 2.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) PMP1_2 PF08114.11 RLN93981.1 - 2.9 7.7 10.9 1.4 8.7 5.4 2.8 2 0 0 2 2 2 0 ATPase proteolipid family Hydrolase_4 PF12146.8 RLN93982.1 - 1.9e-05 24.0 0.1 0.0005 19.4 0.1 2.6 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 RLN93982.1 - 2.7e-05 24.2 0.0 7.3e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 RLN93982.1 - 0.00042 20.1 0.1 0.0011 18.6 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN93982.1 - 0.00061 20.5 0.0 0.0035 18.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF5305 PF17231.2 RLN93982.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) TMEM154 PF15102.6 RLN93982.1 - 0.057 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF2207 PF09972.9 RLN93982.1 - 0.16 10.7 0.4 0.39 9.4 0.2 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) MGC-24 PF05283.11 RLN93982.1 - 0.33 11.4 3.6 0.18 12.2 0.7 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PapJ PF14855.6 RLN93983.1 - 0.084 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone TPR_2 PF07719.17 RLN93984.1 - 1.8e-19 68.2 1.3 4.2e-06 26.4 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 RLN93984.1 - 3.3e-16 58.3 0.6 6.4e-07 28.9 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN93984.1 - 6e-12 44.8 1.7 0.063 13.5 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 RLN93984.1 - 1.5e-11 44.4 1.4 0.97 9.8 0.0 5.3 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN93984.1 - 7.8e-10 38.4 0.6 0.00013 22.1 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN93984.1 - 4.1e-08 32.8 0.0 0.00057 19.5 0.0 3.8 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.6 RLN93984.1 - 3.3e-07 30.6 0.1 0.56 11.2 0.0 5.5 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN93984.1 - 1.1e-06 29.0 3.9 0.1 13.1 0.0 4.4 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.6 RLN93984.1 - 2.3e-06 27.9 7.6 2.1 9.2 0.1 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN93984.1 - 4.1e-05 23.3 2.4 0.012 15.6 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN93984.1 - 6.2e-05 23.6 0.0 0.099 13.3 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN93984.1 - 7.2e-05 22.5 0.1 0.0041 17.0 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN93984.1 - 0.00052 20.2 5.1 0.63 10.3 0.1 3.6 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 RLN93984.1 - 0.0024 18.0 0.0 2.7 8.2 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat Paf67 PF10255.9 RLN93984.1 - 0.061 12.3 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 SPO22 PF08631.10 RLN93984.1 - 0.11 12.0 1.3 1.8 8.0 0.0 2.6 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like TPR_3 PF07720.12 RLN93984.1 - 3 7.9 5.2 12 6.0 2.1 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat MIT PF04212.18 RLN93984.1 - 7.5 6.7 6.5 11 6.2 0.0 3.5 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Ank_2 PF12796.7 RLN93985.1 - 4.8e-22 78.4 8.6 1.4e-05 25.6 0.7 5.3 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN93985.1 - 1.6e-20 73.2 8.5 1.2e-05 25.8 0.3 7.1 6 2 2 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN93985.1 - 4.8e-19 68.2 11.4 0.014 15.7 0.3 8.5 5 2 2 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN93985.1 - 4e-11 42.1 13.3 6.8 7.6 0.1 9.6 9 1 1 10 10 10 3 Ankyrin repeat Ank PF00023.30 RLN93985.1 - 5.5e-05 23.4 7.1 42 4.8 0.1 7.6 7 2 2 9 9 9 0 Ankyrin repeat DUF5049 PF16468.5 RLN93985.1 - 0.0059 16.5 0.1 89 3.1 0.0 4.9 2 1 3 5 5 5 0 Domain of unknown function (DUF5049) DEP PF00610.21 RLN93985.1 - 0.71 10.0 3.8 1.6 8.8 0.0 3.3 4 1 1 5 5 5 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) IQ PF00612.27 RLN93986.1 - 3.2e-39 129.0 111.7 0.00089 18.8 0.0 17.4 17 0 0 17 17 16 14 IQ calmodulin-binding motif EF-hand_1 PF00036.32 RLN93986.1 - 1.7e-13 49.0 2.5 3.1e-06 26.3 0.2 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 RLN93986.1 - 3.1e-13 50.0 3.0 3.1e-13 50.0 3.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN93986.1 - 5.1e-12 44.7 4.4 0.00011 21.6 0.1 3.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RLN93986.1 - 4.7e-11 41.7 2.9 7.7e-05 22.3 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain WW PF00397.26 RLN93986.1 - 9e-11 41.7 13.1 2.4e-06 27.5 1.5 2.6 2 0 0 2 2 2 2 WW domain EF-hand_8 PF13833.6 RLN93986.1 - 8.3e-09 35.2 0.8 2.3e-08 33.8 0.4 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.7 RLN93986.1 - 1.1e-05 25.3 0.2 3.5e-05 23.7 0.2 1.8 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 RLN93986.1 - 0.0015 18.8 0.2 0.0046 17.3 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain RhoGEF67_u1 PF16615.5 RLN93986.1 - 0.99 10.0 3.6 4.5 7.9 0.2 2.8 2 0 0 2 2 2 0 Unstructured region one on RhoGEF 6 and 7 DUF866 PF05907.13 RLN93986.1 - 5.6 6.8 13.7 1.1 9.2 2.1 3.2 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF866) PLU-1 PF08429.11 RLN93987.1 - 8e-17 61.4 23.0 3.1e-12 46.3 12.7 4.2 1 1 1 2 2 2 2 PLU-1-like protein ELM2 PF01448.24 RLN93987.1 - 3.7e-05 24.4 2.4 0.00012 22.7 0.1 3.1 4 0 0 4 4 4 1 ELM2 domain FR47 PF08445.10 RLN93988.1 - 0.0031 17.4 0.0 0.0094 15.9 0.0 1.8 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 RLN93988.1 - 0.0082 16.2 0.0 0.027 14.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RLN93988.1 - 0.0093 15.9 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RLN93988.1 - 0.025 14.8 0.0 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Ipi1_N PF12333.8 RLN93989.1 - 5.8e-12 46.1 0.1 6.2e-11 42.8 0.0 3.0 3 1 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.22 RLN93989.1 - 0.00023 21.2 4.8 0.17 12.3 0.5 4.9 4 0 0 4 4 4 2 HEAT repeat MMS19_N PF14500.6 RLN93989.1 - 0.02 14.5 1.5 0.065 12.8 0.0 2.5 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.6 RLN93989.1 - 0.028 14.8 1.2 0.028 14.8 1.2 4.0 4 0 0 4 4 4 0 HEAT repeats HEAT_EZ PF13513.6 RLN93989.1 - 0.93 10.1 18.2 2.7 8.6 2.3 6.4 5 1 1 6 6 6 0 HEAT-like repeat Mannosyl_trans3 PF11051.8 RLN93990.1 - 1.8e-33 116.1 0.1 2.5e-33 115.6 0.1 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative PH PF00169.29 RLN93990.1 - 0.0024 18.4 0.1 0.0069 16.9 0.1 1.8 1 0 0 1 1 1 1 PH domain TonB_N PF16031.5 RLN93990.1 - 0.014 15.9 23.8 0.014 15.9 23.8 2.3 2 0 0 2 2 2 0 TonB polyproline region Neisseria_TspB PF05616.13 RLN93990.1 - 0.028 12.9 1.7 0.038 12.5 1.7 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein PH_8 PF15409.6 RLN93990.1 - 0.034 14.4 0.7 0.084 13.2 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.6 RLN93990.1 - 0.13 12.7 0.2 0.38 11.2 0.2 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Trypan_PARP PF05887.11 RLN93990.1 - 1.7 8.6 19.9 4 7.4 19.9 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ABC2_membrane_3 PF12698.7 RLN93991.1 - 3.3e-40 138.3 16.9 5.9e-40 137.4 16.9 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 RLN93991.1 - 5.3e-27 95.0 0.0 9.4e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN93991.1 - 8e-08 32.4 0.5 4.8e-06 26.6 0.0 2.6 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RLN93991.1 - 0.042 13.5 0.0 0.37 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF4162 PF13732.6 RLN93991.1 - 0.12 13.2 0.0 42 5.0 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4162) CrgA PF06781.12 RLN93991.1 - 0.32 11.1 2.1 0.57 10.3 1.2 1.9 1 1 0 1 1 1 0 Cell division protein CrgA ABC2_membrane_2 PF12679.7 RLN93991.1 - 6.1 6.0 12.8 16 4.7 9.0 2.7 2 1 1 3 3 3 0 ABC-2 family transporter protein DUF2569 PF10754.9 RLN93991.1 - 9.7 6.6 11.4 3.1 8.2 6.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) BAF1_ABF1 PF04684.13 RLN93992.1 - 0.25 10.3 7.7 0.27 10.2 7.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SAPS PF04499.15 RLN93993.1 - 0.41 9.4 5.8 0.49 9.1 5.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 RLN93993.1 - 5.1 5.8 10.1 6.9 5.3 10.1 1.1 1 0 0 1 1 1 0 Presenilin Smg8_Smg9 PF10220.9 RLN93993.1 - 6.7 4.9 8.9 8.5 4.5 8.9 1.0 1 0 0 1 1 1 0 Smg8_Smg9 CDC27 PF09507.10 RLN93994.1 - 0.12 11.7 25.6 0.17 11.3 25.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PPP4R2 PF09184.11 RLN93994.1 - 0.98 8.9 32.1 1.5 8.3 32.1 1.3 1 0 0 1 1 1 0 PPP4R2 Hamartin PF04388.12 RLN93994.1 - 2.4 6.7 10.4 2.9 6.4 10.4 1.1 1 0 0 1 1 1 0 Hamartin protein Pkinase PF00069.25 RLN93995.1 - 6.7e-40 137.1 0.0 7.1e-36 123.9 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN93995.1 - 1.7e-23 83.2 0.0 4.5e-23 81.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN93995.1 - 4.6e-05 22.9 0.0 9.4e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN93995.1 - 0.00038 19.9 0.0 0.00089 18.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RLN93995.1 - 0.00042 19.2 0.0 0.00084 18.2 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 RLN93995.1 - 0.0073 15.3 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RLN93995.1 - 0.035 14.0 1.0 0.071 13.0 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF4464 PF14713.6 RLN94000.1 - 5.9e-94 313.8 2.6 6.8e-94 313.6 2.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) RGS PF00615.19 RLN94001.1 - 2.2e-06 27.9 0.4 8.7e-06 26.0 0.4 1.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain Cast PF10174.9 RLN94001.1 - 0.04 12.2 0.2 0.046 12.0 0.2 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Acetyltransf_11 PF13720.6 RLN94001.1 - 0.15 12.6 0.3 0.31 11.5 0.3 1.6 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Tropomyosin_1 PF12718.7 RLN94002.1 - 0.0073 16.5 12.0 0.19 11.9 3.3 2.0 1 1 1 2 2 2 2 Tropomyosin like DUF1664 PF07889.12 RLN94002.1 - 0.013 15.5 1.8 0.023 14.8 0.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 RLN94002.1 - 0.044 13.0 4.2 0.05 12.9 4.2 1.0 1 0 0 1 1 1 0 TMPIT-like protein Acyl-CoA_dh_2 PF08028.11 RLN94002.1 - 0.058 13.7 1.0 0.088 13.1 1.0 1.5 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain DUF4164 PF13747.6 RLN94002.1 - 0.12 12.7 7.9 0.28 11.5 7.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) MotA_ExbB PF01618.16 RLN94002.1 - 0.17 11.6 0.8 0.24 11.1 0.7 1.4 1 1 0 1 1 1 0 MotA/TolQ/ExbB proton channel family DUF5320 PF17253.2 RLN94002.1 - 0.18 12.9 2.0 0.23 12.6 1.4 1.5 1 1 1 2 2 2 0 Family of unknown function (DUF5320) APG6_N PF17675.1 RLN94002.1 - 1.5 9.3 12.5 32 5.1 12.5 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Podoplanin PF05808.11 RLN94003.1 - 0.0072 16.4 3.7 0.0072 16.4 3.7 1.9 2 0 0 2 2 2 1 Podoplanin Exo_endo_phos PF03372.23 RLN94003.1 - 0.014 14.9 0.0 0.038 13.5 0.0 1.7 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family T4SS_CagC PF16943.5 RLN94003.1 - 0.081 13.1 0.3 0.2 11.9 0.3 1.6 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system Ribosomal_S14 PF00253.21 RLN94004.1 - 5e-11 42.2 5.1 1.4e-10 40.8 5.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e TMEM131_like PF12371.8 RLN94004.1 - 0.0036 17.5 0.0 0.019 15.2 0.0 2.4 2 0 0 2 2 2 1 Transmembrane protein 131-like STT3 PF02516.14 RLN94005.1 - 6.8e-47 160.5 7.8 6.8e-47 160.5 7.8 1.3 2 0 0 2 2 2 1 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 RLN94005.1 - 0.21 11.8 10.3 0.044 14.0 6.0 1.9 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Chorein_N PF12624.7 RLN94006.1 - 0.0014 18.7 15.7 14 5.9 0.1 5.9 1 1 2 3 3 3 2 N-terminal region of Chorein or VPS13 D_CNTX PF17492.2 RLN94006.1 - 0.026 14.7 3.2 39 4.5 0.1 4.2 1 1 4 5 5 5 0 Delta Ctenitoxins Orf78 PF06024.12 RLN94006.1 - 0.12 12.6 0.0 20 5.5 0.0 3.4 2 2 1 3 3 3 0 Orf78 (ac78) Aa_trans PF01490.18 RLN94007.1 - 6.9e-55 186.4 18.6 8.8e-55 186.1 18.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MMPL PF03176.15 RLN94007.1 - 0.21 10.5 6.7 0.017 14.1 1.6 1.8 2 0 0 2 2 2 0 MMPL family DUF1129 PF06570.11 RLN94007.1 - 7.6 6.0 7.3 3.2 7.2 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Abhydro_lipase PF04083.16 RLN94008.1 - 1.5e-19 69.3 0.0 3.1e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 RLN94008.1 - 1.1e-15 58.0 0.4 1.8e-15 57.3 0.4 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN94008.1 - 2.6e-05 23.6 0.0 4.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 TPR_2 PF07719.17 RLN94009.1 - 2.7e-30 102.0 12.0 0.014 15.4 0.1 10.0 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_1 PF00515.28 RLN94009.1 - 3.5e-27 93.1 12.9 1.7e-06 27.6 0.1 9.4 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 RLN94009.1 - 8.8e-22 77.2 10.0 0.00055 20.2 0.0 8.1 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 RLN94009.1 - 1.3e-18 67.3 3.8 0.0018 18.9 0.0 6.9 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 RLN94009.1 - 1.3e-17 62.4 3.9 0.039 14.2 0.0 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 RLN94009.1 - 3.8e-15 55.3 11.6 0.085 13.7 0.1 9.1 4 3 5 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 RLN94009.1 - 3.2e-13 50.0 13.8 0.0071 16.8 0.1 5.5 4 1 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 RLN94009.1 - 9.7e-10 38.0 7.3 0.049 13.3 0.0 6.9 6 3 3 9 9 9 2 TPR repeat TPR_9 PF13371.6 RLN94009.1 - 1.4e-09 38.0 3.9 0.048 13.8 0.4 6.2 4 2 3 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 RLN94009.1 - 2.1e-08 33.6 12.6 4 7.7 0.1 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN94009.1 - 2.5e-08 33.7 12.8 0.00015 21.9 0.0 7.6 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 RLN94009.1 - 3.4e-08 33.6 9.9 0.16 12.6 0.0 7.9 9 0 0 9 9 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN94009.1 - 0.00011 22.3 13.6 0.49 10.7 0.5 5.0 2 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 RLN94009.1 - 0.00088 18.6 5.5 0.0045 16.2 2.2 3.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN94009.1 - 0.0018 18.0 8.7 0.19 11.7 0.3 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN94009.1 - 0.0087 16.1 3.3 5.7 7.1 0.0 4.5 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.10 RLN94009.1 - 0.087 11.8 0.3 0.44 9.5 0.0 2.1 1 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF4810 PF16068.5 RLN94009.1 - 0.14 12.7 0.0 69 4.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4810) BTAD PF03704.17 RLN94009.1 - 0.64 10.4 4.7 39 4.6 0.1 4.1 5 0 0 5 5 5 0 Bacterial transcriptional activator domain DUF218 PF02698.17 RLN94010.1 - 0.0065 16.5 0.1 2.1 8.4 0.0 2.3 1 1 1 2 2 2 2 DUF218 domain PPR_2 PF13041.6 RLN94011.1 - 1.1e-12 47.9 0.4 5.9e-06 26.4 0.0 5.4 4 2 2 6 6 6 3 PPR repeat family PPR_3 PF13812.6 RLN94011.1 - 5.2e-07 29.6 0.0 0.0008 19.4 0.0 4.4 3 1 1 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.20 RLN94011.1 - 2.1e-06 27.6 0.3 2 8.8 0.0 5.6 6 0 0 6 6 6 2 PPR repeat PPR_long PF17177.4 RLN94011.1 - 7.9e-05 22.1 0.5 0.0097 15.3 0.0 3.5 2 1 1 4 4 4 1 Pentacotripeptide-repeat region of PRORP Med20 PF08612.11 RLN94011.1 - 0.096 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex MFS_1 PF07690.16 RLN94012.1 - 2.7e-30 105.5 29.9 2.7e-30 105.5 29.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 RLN94012.1 - 1.5e-27 96.2 21.4 7.9e-20 70.6 1.2 3.2 1 1 2 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 RLN94012.1 - 2.5e-19 69.5 25.4 2.5e-19 69.5 25.4 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3267 PF11667.8 RLN94012.1 - 0.018 15.3 2.6 0.018 15.3 2.6 4.6 4 1 1 5 5 5 0 Putative zincin peptidase Seryl_tRNA_N PF02403.22 RLN94013.1 - 0.049 13.9 1.9 0.2 11.9 1.9 2.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Cortex-I_coil PF09304.10 RLN94013.1 - 1.4 9.1 10.3 0.63 10.3 6.4 2.5 2 0 0 2 2 2 0 Cortexillin I, coiled coil WD40_4 PF16300.5 RLN94014.1 - 9.8e-31 105.4 0.1 1.5e-17 63.2 0.0 2.7 2 0 0 2 2 2 2 Type of WD40 repeat WD40 PF00400.32 RLN94014.1 - 1.5e-19 70.0 0.5 0.0026 18.6 0.0 7.7 8 0 0 8 8 8 4 WD domain, G-beta repeat DUF1899 PF08953.11 RLN94014.1 - 1.8e-15 56.5 0.1 1.7e-09 37.4 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1899) ANAPC4_WD40 PF12894.7 RLN94014.1 - 6.6e-09 36.0 0.0 0.038 14.3 0.0 4.1 3 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN94014.1 - 0.0082 15.1 0.0 0.51 9.2 0.0 2.7 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF572 PF04502.13 RLN94015.1 - 0.23 11.0 11.1 0.33 10.5 11.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Red1 PF07964.11 RLN94015.1 - 6.1 5.0 10.2 8.8 4.4 10.2 1.3 1 1 0 1 1 1 0 Rec10 / Red1 DEAD PF00270.29 RLN94016.1 - 2.1e-49 167.6 0.0 5.7e-49 166.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN94016.1 - 9.2e-32 109.7 0.0 4e-29 101.2 0.0 2.9 2 1 1 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 RLN94016.1 - 0.015 14.1 0.0 0.21 10.4 0.0 2.5 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AF-4 PF05110.13 RLN94016.1 - 0.037 12.1 15.7 0.052 11.6 15.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CMS1 PF14617.6 RLN94016.1 - 0.15 11.4 0.0 0.15 11.4 0.0 3.9 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit SOBP PF15279.6 RLN94016.1 - 0.67 10.5 6.5 1 9.9 6.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein SelP_N PF04592.14 RLN94016.1 - 0.76 9.1 9.7 1.5 8.2 9.7 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MCM_bind PF09739.9 RLN94016.1 - 6.8 5.0 8.5 11 4.3 8.5 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SRP-alpha_N PF04086.13 RLN94016.1 - 9.7 6.0 19.4 18 5.2 19.4 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Abhydrolase_1 PF00561.20 RLN94017.1 - 1.3e-06 28.3 0.1 2.7e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN94017.1 - 0.00028 20.2 0.2 0.0027 17.0 0.2 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN94017.1 - 0.00028 21.5 3.7 0.009 16.6 0.1 3.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family SIR2 PF02146.17 RLN94018.1 - 1.2e-45 155.7 0.0 1.5e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Sir2 family DUF2529 PF10740.9 RLN94018.1 - 0.029 14.0 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) CH PF00307.31 RLN94019.1 - 1.9e-41 140.7 0.0 1.8e-20 73.1 0.0 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RLN94019.1 - 0.00029 20.6 0.0 0.29 11.0 0.0 2.4 2 0 0 2 2 2 2 CAMSAP CH domain CDC24 PF06395.11 RLN94019.1 - 0.012 15.8 0.1 3.8 7.8 0.0 2.3 2 0 0 2 2 2 0 CDC24 Calponin Pkinase_Tyr PF07714.17 RLN94021.1 - 6.8e-42 143.5 0.0 1.1e-41 142.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN94021.1 - 3.6e-37 128.2 0.0 6.7e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.23 RLN94021.1 - 7.9e-24 82.9 7.8 0.00015 21.7 0.0 7.6 8 0 0 8 8 8 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN94021.1 - 5.6e-07 29.9 15.5 0.00021 21.7 0.2 6.5 5 1 2 7 7 7 4 HEAT-like repeat HEAT_2 PF13646.6 RLN94021.1 - 8e-05 23.0 18.5 0.03 14.7 3.2 4.4 3 2 2 5 5 5 4 HEAT repeats HEAT PF02985.22 RLN94021.1 - 0.00038 20.5 2.2 1.7 9.1 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat Pkinase_fungal PF17667.1 RLN94021.1 - 0.025 13.4 0.0 0.043 12.6 0.0 1.4 1 1 0 1 1 1 0 Fungal protein kinase HEAT_PBS PF03130.16 RLN94021.1 - 1.9 9.4 13.6 38 5.4 0.2 6.2 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat EamA PF00892.20 RLN94022.1 - 4.7e-22 78.6 37.3 2.5e-11 43.9 2.3 3.2 3 0 0 3 3 3 3 EamA-like transporter family SLC35F PF06027.12 RLN94022.1 - 5.3e-13 49.1 18.2 7.7e-13 48.6 16.6 2.0 2 1 0 2 2 2 1 Solute carrier family 35 TPT PF03151.16 RLN94022.1 - 2.9e-07 30.1 8.9 7.4e-07 28.8 8.9 1.7 1 1 0 1 1 1 1 Triose-phosphate Transporter family PUNUT PF16913.5 RLN94022.1 - 8.3e-06 25.2 18.1 1.1e-05 24.8 6.4 3.0 2 1 1 3 3 3 1 Purine nucleobase transmembrane transport UAA PF08449.11 RLN94022.1 - 0.00034 19.9 1.5 0.00034 19.9 1.5 2.6 1 1 1 2 2 2 1 UAA transporter family Sugar_transport PF06800.12 RLN94022.1 - 0.0017 17.8 0.9 0.0017 17.8 0.9 3.4 2 1 0 3 3 3 1 Sugar transport protein DUF2651 PF10852.8 RLN94022.1 - 0.01 16.4 1.2 0.01 16.4 1.2 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF2651) CcmD PF04995.14 RLN94022.1 - 0.046 13.8 0.1 0.046 13.8 0.1 2.7 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) TMEM234 PF10639.9 RLN94022.1 - 3.9 7.6 16.5 0.13 12.3 0.8 3.2 3 1 0 3 3 3 0 Putative transmembrane family 234 PQ-loop PF04193.14 RLN94023.1 - 4.2e-10 39.3 1.6 6e-10 38.7 1.6 1.2 1 0 0 1 1 1 1 PQ loop repeat MtN3_slv PF03083.16 RLN94023.1 - 0.0085 16.1 0.9 0.012 15.6 0.9 1.2 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange SDF PF00375.18 RLN94024.1 - 6.5e-12 45.2 4.8 8.4e-12 44.8 4.8 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family FPN1 PF06963.12 RLN94024.1 - 5.4e-05 21.9 0.4 9e-05 21.2 0.4 1.4 1 0 0 1 1 1 1 Ferroportin1 (FPN1) CPP1-like PF11833.8 RLN94024.1 - 0.51 10.0 3.3 0.53 9.9 1.3 1.8 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Sugar_tr PF00083.24 RLN94025.1 - 2.8e-06 26.5 1.2 3.7e-06 26.1 1.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter PH PF00169.29 RLN94026.1 - 6.5e-17 62.0 0.0 4.6e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 PH domain RabGAP-TBC PF00566.18 RLN94026.1 - 2.9e-09 36.9 0.0 5.3e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_11 PF15413.6 RLN94026.1 - 0.0031 17.9 0.0 0.15 12.4 0.0 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain AA_permease_2 PF13520.6 RLN94026.1 - 0.039 12.8 12.5 0.061 12.1 12.5 1.2 1 0 0 1 1 1 0 Amino acid permease PH_9 PF15410.6 RLN94026.1 - 0.13 12.7 0.0 11 6.4 0.0 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain AA_permease PF00324.21 RLN94026.1 - 0.16 10.5 6.7 0.26 9.9 6.7 1.2 1 0 0 1 1 1 0 Amino acid permease Nop52 PF05997.12 RLN94027.1 - 6e-60 202.7 1.7 6e-60 202.7 1.7 2.3 3 0 0 3 3 3 1 Nucleolar protein,Nop52 cNMP_binding PF00027.29 RLN94029.1 - 1.9e-08 34.3 0.0 3.7e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN94029.1 - 1.3e-06 27.8 23.6 0.00033 20.0 9.0 3.2 3 0 0 3 3 3 2 Ion transport protein Ion_trans_2 PF07885.16 RLN94029.1 - 1.2e-05 25.2 5.1 1.2e-05 25.2 5.1 3.5 4 0 0 4 4 4 2 Ion channel DUF2304 PF10066.9 RLN94029.1 - 0.4 10.9 3.9 0.26 11.5 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Methyltr_RsmB-F PF01189.17 RLN94030.1 - 3.3e-39 134.6 0.0 1.5e-20 73.7 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F PUA PF01472.20 RLN94030.1 - 5.7e-07 29.4 0.2 1.8e-06 27.8 0.1 1.9 2 0 0 2 2 2 1 PUA domain Fibrillarin PF01269.17 RLN94030.1 - 0.0014 17.8 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin FtsJ PF01728.19 RLN94030.1 - 0.0016 18.6 0.0 0.0066 16.6 0.0 1.9 1 1 0 1 1 1 1 FtsJ-like methyltransferase UPF0160 PF03690.13 RLN94031.1 - 5.4e-127 423.8 0.0 6.3e-127 423.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) GTP_CH_N PF12471.8 RLN94031.1 - 0.023 14.5 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal Formin_GBD_N PF18382.1 RLN94031.1 - 0.08 13.4 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Formin N-terminal GTPase-binding domain MutL_C PF08676.11 RLN94031.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 MutL C terminal dimerisation domain 2OG-FeII_Oxy_3 PF13640.6 RLN94033.1 - 0.016 16.1 0.0 0.039 14.9 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Tudor_4 PF18358.1 RLN94033.1 - 0.037 13.6 0.3 12 5.6 0.0 2.5 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain Strep_SA_rep PF06696.11 RLN94033.1 - 0.13 12.3 0.5 0.28 11.2 0.5 1.6 1 0 0 1 1 1 0 Streptococcal surface antigen repeat Peptidase_S10 PF00450.22 RLN94034.1 - 5.8e-120 401.5 0.0 7.2e-120 401.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 RLN94035.1 - 1.4e-43 149.9 0.1 1.6e-43 149.7 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Pkinase PF00069.25 RLN94036.1 - 9e-47 159.6 0.0 1.3e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN94036.1 - 5.6e-40 137.3 0.0 7.7e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mid2 PF04478.12 RLN94036.1 - 0.00067 19.5 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Pkinase_fungal PF17667.1 RLN94036.1 - 0.0064 15.3 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase LapA_dom PF06305.11 RLN94036.1 - 0.092 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Haspin_kinase PF12330.8 RLN94036.1 - 0.16 10.9 0.1 0.31 9.9 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_Tyr PF07714.17 RLN94037.1 - 2.5e-30 105.6 0.0 4e-30 105.0 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN94037.1 - 2.9e-23 82.6 0.0 8.1e-18 64.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain stn_TNFRSF12A PF12191.8 RLN94037.1 - 0.031 14.5 0.3 0.092 13.0 0.3 1.8 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Orthoreo_P10 PF07204.11 RLN94037.1 - 0.18 11.8 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 MIF PF01187.18 RLN94038.1 - 2.2e-24 85.9 0.0 2.4e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 RLN94038.1 - 1.9e-07 30.9 0.0 6.5e-07 29.2 0.0 1.8 2 1 0 2 2 2 1 Tautomerase enzyme MIF PF01187.18 RLN94040.1 - 1.6e-08 34.9 0.2 6.4e-05 23.2 0.2 2.0 1 1 1 2 2 2 2 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 RLN94040.1 - 2e-06 27.6 0.0 0.00057 19.8 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme Tautomerase_2 PF14552.6 RLN94040.1 - 0.0007 19.6 0.0 0.00086 19.4 0.0 1.1 1 0 0 1 1 1 1 Tautomerase enzyme PIF6 PF05341.11 RLN94040.1 - 0.072 13.2 0.1 0.092 12.9 0.1 1.3 1 1 0 1 1 1 0 Per os infectivity factor 6 KorB PF08535.10 RLN94040.1 - 0.15 12.1 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 KorB domain Aldedh PF00171.22 RLN94041.1 - 2.3e-158 527.5 0.0 2.6e-158 527.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DDE_1 PF03184.19 RLN94042.1 - 2.3e-07 30.6 0.0 2.5e-07 30.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease FGGY_C PF02782.16 RLN94043.1 - 1.5e-21 77.1 0.7 3.9e-21 75.7 0.1 2.0 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 RLN94043.1 - 6.9e-21 74.9 0.0 1.1e-11 44.8 0.0 2.3 1 1 1 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Transket_pyr PF02779.24 RLN94044.1 - 2.8e-47 160.7 0.3 5.9e-47 159.6 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 RLN94044.1 - 2.9e-19 69.2 0.0 6.4e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DENN PF02141.21 RLN94045.1 - 7.8e-29 101.0 0.1 1.2e-28 100.4 0.1 1.2 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 RLN94046.1 - 3.8e-09 37.2 0.1 1.3e-08 35.4 0.1 2.0 1 0 0 1 1 1 1 uDENN domain Biotin_lipoyl PF00364.22 RLN94047.1 - 7.1e-21 73.8 0.6 1.1e-20 73.2 0.6 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 RLN94047.1 - 0.0017 18.1 2.6 0.054 13.3 0.4 2.3 2 0 0 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 RLN94047.1 - 0.022 14.0 0.1 0.032 13.4 0.1 1.3 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Orthopox_A5L PF06193.11 RLN94047.1 - 0.067 12.6 1.6 0.075 12.5 1.6 1.1 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like ARHGEF5_35 PF15441.6 RLN94047.1 - 2.8 6.8 5.5 3.8 6.4 5.5 1.1 1 0 0 1 1 1 0 Rho guanine nucleotide exchange factor 5/35 Porin_3 PF01459.22 RLN94048.1 - 4.4e-46 157.5 0.1 5e-46 157.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Whirly PF08536.11 RLN94049.1 - 0.0011 18.8 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Whirly transcription factor Ebp2 PF05890.12 RLN94050.1 - 6.5e-37 127.5 5.2 8e-37 127.3 5.2 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Glyco_hydro_32N PF00251.20 RLN94052.1 - 2.4e-43 148.9 3.5 4.1e-43 148.1 3.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 RLN94052.1 - 7.2e-25 87.8 0.5 1.1e-24 87.2 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.6 RLN94052.1 - 0.00019 20.9 0.2 0.00038 19.8 0.2 1.4 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 RLN94052.1 - 0.11 12.6 1.1 0.68 10.2 0.6 2.8 2 0 0 2 2 2 0 BNR/Asp-box repeat DUF4975 PF16346.5 RLN94052.1 - 0.11 12.5 0.1 0.95 9.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4975) PAP_central PF04928.17 RLN94053.1 - 1.2e-69 234.1 0.1 3.4e-69 232.6 0.0 1.7 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 RLN94053.1 - 1e-07 31.8 0.2 5.3e-07 29.4 0.2 2.1 1 1 1 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 RLN94053.1 - 3.6e-07 30.4 0.0 7.5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4269 PF14091.6 RLN94053.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) Peptidase_M8 PF01457.16 RLN94054.1 - 6.5e-65 219.8 18.7 9.8e-47 159.8 10.9 3.3 2 1 0 3 3 3 3 Leishmanolysin NTP_transferase PF00483.23 RLN94055.1 - 4.4e-45 154.2 0.0 8.9e-45 153.2 0.0 1.5 1 1 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 RLN94055.1 - 1.4e-07 30.9 2.7 3.4e-07 29.7 2.7 1.7 1 0 0 1 1 1 1 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 RLN94055.1 - 2.3e-06 28.1 0.0 2.9e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 RLN94055.1 - 0.032 14.0 4.6 0.035 13.8 2.8 2.1 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase IFT46_B_C PF12317.8 RLN94056.1 - 2.6e-93 311.6 0.1 4.1e-93 311.0 0.1 1.3 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal MULE PF10551.9 RLN94057.1 - 4.1e-11 43.1 0.5 1.1e-10 41.7 0.5 1.8 1 0 0 1 1 1 1 MULE transposase domain DUF3907 PF13047.6 RLN94057.1 - 0.066 13.2 1.3 0.21 11.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3907) SWIM PF04434.17 RLN94057.1 - 0.066 12.9 1.9 0.18 11.5 1.9 1.7 1 0 0 1 1 1 0 SWIM zinc finger SSP160 PF06933.11 RLN94057.1 - 3.6 5.7 12.4 5.9 5.0 12.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Arm PF00514.23 RLN94058.1 - 1.1e-23 82.4 20.1 1.6e-08 34.3 0.3 8.0 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 RLN94058.1 - 4.4e-10 39.0 0.1 1e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 Atypical Arm repeat IBB PF01749.20 RLN94058.1 - 2.7e-06 27.7 1.8 7.3e-06 26.3 0.6 2.1 2 0 0 2 2 2 1 Importin beta binding domain HEAT_2 PF13646.6 RLN94058.1 - 3.2e-06 27.4 2.5 0.18 12.2 0.0 4.9 3 2 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 RLN94058.1 - 4.7e-06 27.0 8.3 0.23 12.0 0.1 4.9 4 0 0 4 4 4 3 HEAT-like repeat V-ATPase_H_C PF11698.8 RLN94058.1 - 0.04 14.0 0.0 2.2 8.4 0.0 2.6 2 0 0 2 2 2 0 V-ATPase subunit H HEAT_PBS PF03130.16 RLN94058.1 - 0.11 13.2 2.7 23 6.0 0.1 4.8 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat HEAT PF02985.22 RLN94058.1 - 2.3 8.7 14.6 3 8.3 0.0 6.2 8 0 0 8 8 8 0 HEAT repeat E1-E2_ATPase PF00122.20 RLN94059.1 - 7.8e-42 142.8 1.6 7.8e-42 142.8 1.6 3.2 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 RLN94059.1 - 5.6e-36 124.0 0.7 5.6e-36 124.0 0.7 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 RLN94059.1 - 1.2e-19 71.5 1.4 1.5e-15 58.1 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN94059.1 - 8.6e-17 61.0 0.0 4.8e-16 58.6 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 RLN94059.1 - 3.4e-15 55.5 0.0 7.6e-15 54.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RLN94059.1 - 0.0088 15.8 1.0 0.0088 15.8 1.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 RLN94059.1 - 0.15 12.5 0.2 0.51 10.7 0.2 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pkinase_Tyr PF07714.17 RLN94061.1 - 1e-41 143.0 0.0 2e-41 142.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN94061.1 - 3.5e-36 124.9 0.0 7.7e-36 123.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.23 RLN94061.1 - 1.3e-09 37.8 0.3 0.0047 16.9 0.0 4.1 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Brr6_like_C_C PF10104.9 RLN94061.1 - 0.0099 15.7 0.1 0.021 14.6 0.1 1.5 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Kdo PF06293.14 RLN94061.1 - 0.031 13.6 0.7 0.071 12.5 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN94061.1 - 0.046 13.6 4.5 0.056 13.4 0.0 2.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family ABC1 PF03109.16 RLN94061.1 - 0.048 13.8 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 ABC1 family zinc_ribbon_15 PF17032.5 RLN94061.1 - 0.061 14.1 0.8 0.15 12.8 0.8 1.7 1 0 0 1 1 1 0 zinc-ribbon family RIO1 PF01163.22 RLN94061.1 - 0.11 12.1 0.3 0.39 10.3 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Phostensin PF13914.6 RLN94062.1 - 0.17 12.5 0.5 0.31 11.7 0.5 1.3 1 0 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region PTN13_u3 PF16599.5 RLN94062.1 - 1.6 8.7 6.8 4.9 7.2 6.9 1.7 1 1 0 1 1 1 0 Unstructured linker region on PTN13 protein between PDZ Trp_halogenase PF04820.14 RLN94063.1 - 0.013 14.4 0.0 0.015 14.2 0.0 1.0 1 0 0 1 1 1 0 Tryptophan halogenase ABC2_membrane PF01061.24 RLN94064.1 - 8.6e-34 116.8 23.8 1.8e-33 115.7 23.8 1.6 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN94064.1 - 1.4e-24 87.2 0.1 2.2e-24 86.5 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN94064.1 - 1.4e-06 28.4 0.0 0.031 14.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 RLN94064.1 - 0.0026 17.5 0.1 0.69 9.6 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein SMC_N PF02463.19 RLN94064.1 - 0.0045 16.4 0.0 2.9 7.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RLN94064.1 - 0.0047 17.3 0.2 0.01 16.2 0.2 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 RLN94064.1 - 0.0069 16.1 0.1 0.019 14.7 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN94064.1 - 0.0078 16.1 0.2 0.017 15.0 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 RLN94064.1 - 0.074 13.5 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 RLN94064.1 - 0.15 11.0 0.1 0.27 10.2 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 RLN94064.1 - 0.2 11.2 0.2 0.49 9.9 0.1 1.6 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 RLN94064.1 - 1.1 8.3 23.7 1.9 7.5 23.7 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein MPS2 PF17060.5 RLN94065.1 - 0.054 12.8 4.8 0.066 12.5 4.8 1.0 1 0 0 1 1 1 0 Monopolar spindle protein 2 Sugar_tr PF00083.24 RLN94066.1 - 6.4e-106 354.9 24.3 7.3e-106 354.7 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN94066.1 - 2.2e-27 95.9 52.5 1.2e-24 86.9 26.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily PhetRS_B1 PF18262.1 RLN94067.1 - 1.3e-09 38.1 0.2 3.2e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain Chromo PF00385.24 RLN94069.1 - 0.0046 16.8 0.2 0.024 14.5 0.2 2.0 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1816 PF08846.10 RLN94069.1 - 0.04 13.9 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) Mtf2_C PF14061.6 RLN94069.1 - 0.096 12.9 0.2 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 Sugar_tr PF00083.24 RLN94070.1 - 1.6e-103 347.0 21.3 1.8e-103 346.8 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN94070.1 - 5.8e-26 91.3 32.4 4.7e-20 71.8 9.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily 7TM-7TMR_HD PF07698.11 RLN94070.1 - 0.028 14.2 1.0 0.028 14.2 1.0 3.1 3 2 0 3 3 3 0 7TM receptor with intracellular HD hydrolase Esterase PF00756.20 RLN94071.1 - 1.1e-09 38.3 4.1 8e-09 35.5 4.1 2.1 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 RLN94071.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DEAD PF00270.29 RLN94072.1 - 3.9e-43 147.2 0.0 9.1e-43 146.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN94072.1 - 6.3e-23 81.2 0.0 2e-22 79.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 RLN94072.1 - 3.1e-17 62.6 0.1 7e-17 61.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 RLN94072.1 - 6.6e-06 26.2 0.1 8.5e-05 22.6 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4746 PF15928.5 RLN94072.1 - 5.8 6.3 32.3 0.06 12.8 8.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DUF1664 PF07889.12 RLN94072.1 - 8.3 6.5 6.9 25 4.9 6.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Vps51 PF08700.11 RLN94073.1 - 2.7e-23 81.8 0.2 4.4e-23 81.2 0.2 1.3 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 RLN94073.1 - 8.7e-07 27.9 0.3 1e-06 27.7 0.3 1.1 1 0 0 1 1 1 1 Dor1-like family COG2 PF06148.11 RLN94073.1 - 3.2e-05 24.0 0.3 4e-05 23.7 0.3 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 RLN94073.1 - 0.0011 19.1 0.3 0.0021 18.3 0.2 1.6 1 1 1 2 2 2 1 Golgi transport complex subunit 5 LIF_OSM PF01291.17 RLN94073.1 - 0.0015 18.7 0.0 0.0019 18.4 0.0 1.1 1 0 0 1 1 1 1 LIF / OSM family BORCS6 PF10157.9 RLN94073.1 - 0.0046 17.2 0.5 0.0056 16.9 0.5 1.2 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 HIP1_clath_bdg PF16515.5 RLN94073.1 - 0.0079 16.8 1.2 0.0091 16.6 0.2 1.6 2 0 0 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 LOH1CR12 PF10158.9 RLN94073.1 - 0.013 15.6 0.2 0.025 14.6 0.2 1.6 1 0 0 1 1 1 0 Tumour suppressor protein Arg_decarbox_C PF17944.1 RLN94074.1 - 0.032 14.8 0.1 1.1 9.9 0.0 2.3 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension PIG-S PF10510.9 RLN94076.1 - 6e-111 371.8 5.3 6.9e-111 371.6 5.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DUF1778 PF08681.11 RLN94076.1 - 0.0076 16.1 0.8 1.2 9.1 0.2 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1778) LINES_C PF14695.6 RLN94076.1 - 0.065 12.7 0.1 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 Lines C-terminus DUF3209 PF11483.8 RLN94076.1 - 0.21 12.1 1.6 0.5 10.8 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3209) SR-25 PF10500.9 RLN94077.1 - 0.16 11.5 8.5 0.24 11.0 8.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-FCS PF06467.14 RLN94080.1 - 0.052 13.5 2.2 0.052 13.5 2.2 2.1 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif PLATZ PF04640.14 RLN94080.1 - 0.32 11.7 3.1 0.81 10.4 3.1 1.7 1 1 0 1 1 1 0 PLATZ transcription factor FYVE_2 PF02318.16 RLN94081.1 - 7.5e-07 29.4 28.0 0.0012 19.1 8.3 3.4 2 1 1 3 3 3 3 FYVE-type zinc finger FYVE PF01363.21 RLN94081.1 - 1.1e-06 28.7 29.9 0.00061 19.9 12.4 2.7 2 0 0 2 2 2 2 FYVE zinc finger DUF659 PF04937.15 RLN94083.1 - 3.5e-05 23.7 0.0 6.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Sugar_tr PF00083.24 RLN94084.1 - 1.5e-33 116.3 22.2 9.2e-32 110.5 22.2 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN94084.1 - 1.6e-32 112.8 28.9 5.3e-29 101.2 22.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 RLN94084.1 - 0.0049 15.2 8.2 0.1 10.8 1.1 2.5 2 0 0 2 2 2 2 BT1 family DUF1435 PF07256.12 RLN94084.1 - 0.14 12.2 7.7 0.086 12.9 3.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) Kinesin PF00225.23 RLN94085.1 - 6.5e-59 199.5 0.0 9.3e-59 199.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN94085.1 - 2.3e-06 27.6 0.0 5.5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding AAA_7 PF12775.7 RLN94085.1 - 0.0027 17.3 0.1 0.0059 16.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 RLN94085.1 - 0.003 17.8 0.4 0.11 12.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 RLN94085.1 - 0.0049 17.3 0.0 0.013 15.9 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN94085.1 - 0.01 16.2 0.0 0.038 14.4 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 RLN94085.1 - 0.024 14.3 0.0 0.082 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 RLN94085.1 - 0.11 12.1 0.1 0.56 9.8 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ResIII PF04851.15 RLN94085.1 - 0.11 12.5 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit V-SNARE_C PF12352.8 RLN94086.1 - 1.5e-11 44.4 5.1 1.5e-11 44.4 5.1 1.9 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 RLN94086.1 - 0.0062 16.4 0.4 0.01 15.7 0.4 1.3 1 0 0 1 1 1 1 Sec20 Synaptobrevin PF00957.21 RLN94086.1 - 0.18 11.6 2.6 0.39 10.5 2.6 1.5 1 1 0 1 1 1 0 Synaptobrevin Orf78 PF06024.12 RLN94086.1 - 0.19 12.0 2.0 0.23 11.8 2.0 1.4 1 1 0 1 1 1 0 Orf78 (ac78) ABC2_membrane PF01061.24 RLN94088.1 - 1e-39 136.2 25.4 1e-39 136.2 25.4 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RLN94088.1 - 9.9e-17 61.7 0.0 1.8e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 RLN94088.1 - 0.0002 21.8 0.1 0.001 19.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 RLN94088.1 - 0.0072 16.2 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN94088.1 - 0.014 15.1 0.2 0.035 13.9 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 RLN94088.1 - 0.014 14.6 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 RLN94088.1 - 0.022 14.4 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain PDR_assoc PF08370.11 RLN94088.1 - 0.03 14.1 0.6 0.03 14.1 0.6 2.4 2 0 0 2 2 2 0 Plant PDR ABC transporter associated AAA_5 PF07728.14 RLN94088.1 - 0.052 13.6 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) VirE PF05272.11 RLN94088.1 - 0.052 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E AAA_22 PF13401.6 RLN94088.1 - 0.054 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 RLN94088.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 MMR_HSR1 PF01926.23 RLN94088.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF815 PF05673.13 RLN94088.1 - 0.18 11.0 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Roc PF08477.13 RLN94088.1 - 0.19 11.9 0.1 0.66 10.2 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC2_membrane_3 PF12698.7 RLN94088.1 - 0.71 8.9 19.0 0.013 14.7 10.9 2.0 2 1 0 2 2 2 0 ABC-2 family transporter protein GLTP PF08718.11 RLN94091.1 - 2.8e-23 82.9 0.0 6.2e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) FYVE PF01363.21 RLN94091.1 - 7.5e-10 38.8 15.6 2e-09 37.4 15.6 1.7 1 0 0 1 1 1 1 FYVE zinc finger Bd3614-deam PF14439.6 RLN94091.1 - 0.0086 16.2 0.5 0.021 14.9 0.5 1.6 1 0 0 1 1 1 1 Bd3614-like deaminase zf-AD PF07776.15 RLN94091.1 - 0.05 13.8 3.4 0.54 10.5 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) FYVE_2 PF02318.16 RLN94091.1 - 0.45 10.7 12.8 0.066 13.4 8.4 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger Ta0938 PF11494.8 RLN94091.1 - 2 8.8 4.0 2.3 8.5 2.3 2.0 2 0 0 2 2 2 0 Ta0938 zf-B_box PF00643.24 RLN94091.1 - 3.7 7.8 9.8 0.62 10.3 5.3 2.1 2 0 0 2 2 2 0 B-box zinc finger NifU_N PF01592.16 RLN94092.1 - 4.4e-55 185.3 0.2 5.3e-55 185.0 0.2 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain PTPLA PF04387.14 RLN94093.1 - 1.3e-53 181.1 8.6 1.8e-53 180.6 8.6 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA P5CR_dimer PF14748.6 RLN94093.1 - 0.11 12.7 0.4 0.17 12.2 0.4 1.2 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation ADK PF00406.22 RLN94094.1 - 9.2e-52 175.1 0.0 1.1e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.14 RLN94094.1 - 3.1e-19 68.7 0.0 5.7e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 RLN94094.1 - 5.5e-17 62.5 0.0 1e-16 61.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Podoplanin PF05808.11 RLN94095.1 - 0.00012 22.3 2.6 0.00012 22.3 2.6 2.2 1 1 1 2 2 2 1 Podoplanin NMD3 PF04981.13 RLN94096.1 - 9.1e-70 234.9 5.7 1.5e-69 234.2 5.7 1.4 1 0 0 1 1 1 1 NMD3 family CxC5 PF18718.1 RLN94096.1 - 0.0024 18.0 0.5 0.0049 16.9 0.5 1.4 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases Myc_N PF01056.18 RLN94096.1 - 0.16 11.8 3.8 0.33 10.8 3.8 1.5 1 0 0 1 1 1 0 Myc amino-terminal region Pox_Ag35 PF03286.14 RLN94096.1 - 0.28 10.9 7.3 0.44 10.3 7.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PRCC PF10253.9 RLN94097.1 - 1.1e-06 29.7 24.1 1.1e-06 29.7 24.1 2.8 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Gp_dh_C PF02800.20 RLN94098.1 - 2.3e-69 232.0 0.0 2.7e-69 231.8 0.0 1.0 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain fn3 PF00041.21 RLN94099.1 - 1.4e-05 25.3 0.3 2.8e-05 24.4 0.3 1.5 1 0 0 1 1 1 1 Fibronectin type III domain CBM_2 PF00553.19 RLN94099.1 - 0.088 13.1 5.8 0.29 11.5 0.4 3.0 2 1 0 3 3 3 0 Cellulose binding domain PLAC8 PF04749.17 RLN94102.1 - 5.7e-06 27.3 7.1 1.1e-05 26.3 4.7 2.5 2 1 0 2 2 2 1 PLAC8 family MpPF26 PF07666.11 RLN94102.1 - 0.41 10.8 2.3 0.64 10.1 2.3 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 26 HrpB4 PF09502.10 RLN94103.1 - 0.076 12.8 0.0 0.14 12.0 0.0 1.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB4) Pkinase_Tyr PF07714.17 RLN94104.1 - 1.4e-06 27.8 0.0 1.6e-06 27.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN94104.1 - 0.014 14.7 0.0 0.016 14.6 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain RNA_pol_Rpb1_5 PF04998.17 RLN94105.1 - 4.2e-94 314.9 0.2 7.9e-94 314.0 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 RLN94105.1 - 3.9e-65 219.1 0.1 7.3e-65 218.2 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 RLN94105.1 - 5.4e-33 114.1 0.0 5.5e-32 110.9 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 RLN94105.1 - 4.5e-19 68.4 0.0 1.5e-18 66.7 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.12 RLN94105.1 - 0.003 17.0 0.8 0.22 10.8 0.2 3.1 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 DUF3043 PF11241.8 RLN94105.1 - 5.1 7.1 6.7 1.1 9.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) zf-C2H2_12 PF18658.1 RLN94106.1 - 0.066 12.8 1.0 0.9 9.2 0.0 2.8 3 0 0 3 3 3 0 Zinc-finger C2H2-type p25-alpha PF05517.12 RLN94107.1 - 0.1 12.8 0.0 0.28 11.3 0.0 1.7 2 1 0 2 2 2 0 p25-alpha DUSP PF06337.12 RLN94109.1 - 1.2e-08 35.4 0.0 2.7e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 DUSP domain Cellulose_synt PF03552.14 RLN94109.1 - 0.06 11.8 2.0 0.088 11.3 2.0 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF913 PF06025.12 RLN94109.1 - 0.21 10.5 0.1 0.33 9.9 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ANAPC15 PF15243.6 RLN94109.1 - 1.4 9.4 14.2 5.5 7.5 0.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 FAM176 PF14851.6 RLN94109.1 - 3.7 7.2 14.1 4.3 7.0 11.0 2.1 2 0 0 2 2 2 0 FAM176 family S-antigen PF05756.11 RLN94109.1 - 4.4 7.7 8.2 9.3 6.7 8.2 1.5 1 0 0 1 1 1 0 S-antigen protein DUF2956 PF11169.8 RLN94109.1 - 5.3 7.3 9.2 16 5.8 9.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Ribosomal_L19e PF01280.20 RLN94110.1 - 0.037 14.1 3.3 0.043 13.9 1.8 1.8 2 0 0 2 2 2 0 Ribosomal protein L19e Aa_trans PF01490.18 RLN94111.1 - 3.8e-08 32.5 0.1 4.3e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TMEM192 PF14802.6 RLN94111.1 - 0.093 11.8 1.1 0.17 11.0 0.1 1.8 2 0 0 2 2 2 0 TMEM192 family DUF2157 PF09925.9 RLN94111.1 - 1.3 8.8 3.5 0.69 9.7 0.2 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) NADH5_C PF06455.11 RLN94111.1 - 1.9 8.0 5.8 0.16 11.6 0.4 1.7 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus peroxidase PF00141.23 RLN94113.1 - 3.9e-75 252.5 0.0 6.3e-47 160.2 0.0 2.8 2 1 0 2 2 2 2 Peroxidase peroxidase PF00141.23 RLN94114.1 - 3.9e-75 252.5 0.0 6.3e-47 160.2 0.0 2.8 2 1 0 2 2 2 2 Peroxidase RabGAP-TBC PF00566.18 RLN94115.1 - 1.2e-25 90.4 2.2 3.5e-21 75.9 0.3 2.2 1 1 1 2 2 2 2 Rab-GTPase-TBC domain DUF4864 PF16156.5 RLN94115.1 - 0.06 14.0 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) Ins_allergen_rp PF06757.13 RLN94115.1 - 0.095 12.7 0.1 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification DUF515 PF04415.12 RLN94116.1 - 0.55 8.6 13.3 0.66 8.3 13.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) CDK2AP PF09806.9 RLN94116.1 - 3.3 7.7 14.8 0.66 10.0 11.0 1.6 1 1 1 2 2 2 0 Cyclin-dependent kinase 2-associated protein Cation_ATPase_C PF00689.21 RLN94117.1 - 4.4e-50 169.9 0.7 5.4e-50 169.6 0.7 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Bac_export_1 PF01311.20 RLN94117.1 - 0.011 15.3 1.9 0.011 15.3 1.9 2.0 2 0 0 2 2 2 0 Bacterial export proteins, family 1 FA_desaturase PF00487.24 RLN94117.1 - 0.051 13.4 0.3 0.051 13.4 0.3 1.9 2 0 0 2 2 2 0 Fatty acid desaturase bZIP_1 PF00170.21 RLN94118.1 - 5.4e-08 32.8 15.3 1e-07 32.0 15.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RLN94118.1 - 5.4e-06 26.4 12.8 1.5e-05 24.9 12.8 1.8 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 RLN94118.1 - 0.00055 20.4 10.4 0.0015 19.0 10.4 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor FapA PF03961.13 RLN94118.1 - 0.02 13.5 1.0 0.029 13.0 1.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 RLN94118.1 - 0.25 9.2 2.7 0.36 8.7 2.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Csm1_N PF18504.1 RLN94118.1 - 0.51 10.7 7.5 0.61 10.5 3.8 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain Seryl_tRNA_N PF02403.22 RLN94118.1 - 0.67 10.2 7.3 1.1 9.5 5.9 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HIP1_clath_bdg PF16515.5 RLN94118.1 - 0.99 10.1 19.2 25 5.6 13.3 3.6 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YabA PF06156.13 RLN94118.1 - 7.5 7.2 6.7 3.9 8.2 2.6 2.5 3 1 0 3 3 3 0 Initiation control protein YabA CAF1 PF04857.20 RLN94119.1 - 4.8e-66 223.1 0.0 1.7e-65 221.3 0.0 1.7 1 1 0 1 1 1 1 CAF1 family ribonuclease RPN2_C PF18004.1 RLN94119.1 - 1.5 8.7 4.4 2.7 7.9 4.4 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Ribonuclease_3 PF00636.26 RLN94121.1 - 3.8e-34 117.5 0.0 1.1e-15 58.1 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 RLN94121.1 - 6e-21 74.4 0.5 3.7e-20 71.9 0.2 2.5 2 1 0 2 2 2 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 RLN94121.1 - 4.7e-19 68.8 0.2 1.9e-08 34.5 0.0 4.7 5 1 0 5 5 5 3 Ribonuclease-III-like DUF848 PF05852.11 RLN94121.1 - 0.034 14.2 0.1 0.18 11.9 0.1 2.2 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) CDC45 PF02724.14 RLN94121.1 - 0.12 10.6 2.0 0.19 10.0 2.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RLN94121.1 - 5.3 5.1 7.7 11 4.1 4.9 2.0 2 0 0 2 2 2 0 Nop14-like family H2O2_YaaD PF03883.14 RLN94122.1 - 1e-26 93.9 0.6 6.2e-20 71.7 0.1 2.2 1 1 1 2 2 2 2 Peroxide stress protein YaaA NAD_binding_3 PF03447.16 RLN94122.1 - 0.013 16.1 0.9 0.021 15.5 0.1 1.7 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain MCD PF05292.11 RLN94124.1 - 6.7e-73 245.4 0.2 2.2e-72 243.7 0.2 1.8 1 1 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain EF-hand_1 PF00036.32 RLN94124.1 - 5.3e-08 31.9 3.7 1.3e-06 27.6 0.7 3.0 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 RLN94124.1 - 1.6e-06 27.9 1.7 0.012 15.5 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 RLN94124.1 - 1.3e-05 25.5 0.5 0.00025 21.4 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN94124.1 - 8.2e-05 22.2 0.6 0.003 17.4 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 RLN94124.1 - 0.00033 20.0 0.8 0.0016 17.9 0.7 2.1 2 0 0 2 2 2 1 EF hand SIX1_SD PF16878.5 RLN94124.1 - 0.11 13.0 0.0 0.34 11.4 0.0 1.9 1 1 0 1 1 1 0 Transcriptional regulator, SIX1, N-terminal SD domain WD40 PF00400.32 RLN94125.1 - 2.4e-07 31.3 2.2 3.1 8.8 0.0 5.2 4 1 0 4 4 4 3 WD domain, G-beta repeat zf-CHC2 PF01807.20 RLN94125.1 - 0.11 12.4 0.3 12 5.8 0.0 2.4 1 1 1 2 2 2 0 CHC2 zinc finger MULE PF10551.9 RLN94127.1 - 4.5e-12 46.2 0.1 1.2e-11 44.8 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 RLN94127.1 - 0.021 15.5 0.1 0.051 14.3 0.1 1.7 1 0 0 1 1 1 0 FAR1 DNA-binding domain Dimer_Tnp_hAT PF05699.14 RLN94128.1 - 1.5e-05 24.7 0.0 4.7e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region LZ3wCH PF18517.1 RLN94128.1 - 0.19 11.8 0.1 1.2 9.3 0.0 2.1 2 0 0 2 2 2 0 Leucine zipper with capping helix domain DUF659 PF04937.15 RLN94129.1 - 0.019 14.8 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) DUF1697 PF08002.11 RLN94130.1 - 0.12 12.8 0.0 1 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1697) Crp PF00325.20 RLN94130.1 - 0.44 10.3 2.6 41 3.9 0.0 3.7 4 0 0 4 4 4 0 Bacterial regulatory proteins, crp family Mito_carr PF00153.27 RLN94131.1 - 3.8e-54 180.6 6.0 4.3e-21 74.6 0.2 3.7 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 RLN94131.1 - 0.0081 15.4 3.6 0.11 11.6 0.2 3.0 2 1 0 3 3 3 1 Gammaproteobacterial serine protease DnaJ PF00226.31 RLN94132.1 - 1.3e-12 47.6 0.0 4.4e-12 45.9 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain PALP PF00291.25 RLN94133.1 - 2e-61 208.0 3.4 4.9e-61 206.7 3.4 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Catalase PF00199.19 RLN94135.1 - 2.1e-187 622.9 0.1 2.6e-187 622.6 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 RLN94135.1 - 2.2e-19 69.4 0.5 9.3e-19 67.4 0.2 2.2 2 0 0 2 2 2 1 Catalase-related immune-responsive PTA_PTB PF01515.19 RLN94139.1 - 4.7e-116 387.6 0.1 7.4e-116 386.9 0.1 1.3 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase AAA_26 PF13500.6 RLN94139.1 - 1.6e-19 70.6 0.0 2.7e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DRTGG PF07085.12 RLN94139.1 - 1.6e-16 60.0 0.0 4.5e-16 58.5 0.0 1.9 1 0 0 1 1 1 1 DRTGG domain PTA_PTB PF01515.19 RLN94140.1 - 1.2e-113 379.6 0.3 1.9e-113 379.0 0.3 1.3 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase AAA_26 PF13500.6 RLN94140.1 - 2e-17 63.7 0.0 3.4e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DRTGG PF07085.12 RLN94140.1 - 2.3e-15 56.2 0.1 9.7e-15 54.3 0.1 2.1 2 0 0 2 2 2 1 DRTGG domain Pkinase_Tyr PF07714.17 RLN94141.1 - 7.9e-43 146.6 0.0 1.2e-42 146.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN94141.1 - 2.9e-37 128.5 0.0 4.4e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pectinesterase PF01095.19 RLN94141.1 - 0.12 11.1 0.2 0.21 10.3 0.2 1.3 1 0 0 1 1 1 0 Pectinesterase UvrA_DNA-bind PF17755.1 RLN94141.1 - 0.15 12.4 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 UvrA DNA-binding domain DivIVA PF05103.13 RLN94142.1 - 0.017 15.2 0.0 0.061 13.4 0.0 1.9 1 0 0 1 1 1 0 DivIVA protein dsrm PF00035.26 RLN94143.1 - 1.2e-07 32.3 0.5 0.002 18.8 0.0 2.9 2 0 0 2 2 2 2 Double-stranded RNA binding motif Fis1_TPR_C PF14853.6 RLN94143.1 - 0.0019 18.2 0.3 0.0067 16.5 0.3 1.9 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 RLN94143.1 - 0.0087 16.1 8.7 0.01 15.9 0.8 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN94143.1 - 0.024 15.2 1.8 0.024 15.2 1.8 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN94143.1 - 0.05 14.4 3.6 0.068 14.0 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_U32_C PF16325.5 RLN94143.1 - 0.066 13.5 0.1 0.2 12.0 0.1 1.8 1 0 0 1 1 1 0 Peptidase family U32 C-terminal domain TPR_17 PF13431.6 RLN94143.1 - 0.11 13.0 2.1 0.71 10.4 0.7 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN94143.1 - 0.25 11.2 5.8 2 8.4 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Kazal_1 PF00050.21 RLN94144.1 - 3.7e-17 62.1 10.8 1.4e-08 34.7 1.3 2.5 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 RLN94144.1 - 1.4e-15 57.2 12.3 1.4e-08 34.7 2.7 2.4 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain BTB_2 PF02214.22 RLN94144.1 - 1.4e-10 41.3 0.0 2.6e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain HPTransfase PF10090.9 RLN94144.1 - 0.11 12.3 0.4 4.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Histidine phosphotransferase C-terminal domain His_Phos_2 PF00328.22 RLN94145.1 - 1.2e-11 44.7 0.0 2.8e-07 30.2 0.0 2.4 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Glyco_hydro_63 PF03200.16 RLN94146.1 - 1.4e-165 551.8 0.2 1.4e-163 545.2 0.2 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 RLN94146.1 - 4.6e-30 105.4 0.0 8.9e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 RLN94146.1 - 0.037 12.9 0.4 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Trehalase TctC PF03401.14 RLN94147.1 - 0.21 10.6 0.0 0.38 9.8 0.0 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor SEO_C PF14577.6 RLN94149.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Sieve element occlusion C-terminus PPR_2 PF13041.6 RLN94150.1 - 1.2e-09 38.2 0.0 1.2e-06 28.6 0.0 2.2 1 1 1 2 2 2 2 PPR repeat family PPR_1 PF12854.7 RLN94150.1 - 4.9e-09 35.7 0.1 0.00016 21.3 0.0 2.6 2 0 0 2 2 2 2 PPR repeat PPR_3 PF13812.6 RLN94150.1 - 7.8e-08 32.3 0.0 2e-06 27.8 0.0 2.6 2 1 0 2 2 2 1 Pentatricopeptide repeat domain PPR PF01535.20 RLN94150.1 - 0.02 15.1 0.0 0.74 10.2 0.0 2.8 2 0 0 2 2 2 0 PPR repeat COX5A PF02284.16 RLN94150.1 - 0.15 12.1 0.1 0.27 11.2 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va DNA_pol_A_exo1 PF01612.20 RLN94151.1 - 1.7e-15 57.2 0.0 6.3e-15 55.3 0.0 2.0 1 1 0 1 1 1 1 3'-5' exonuclease Ank_2 PF12796.7 RLN94152.1 - 0.028 15.0 0.0 0.061 13.9 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN94152.1 - 0.14 12.8 0.0 0.35 11.5 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) PIG-H PF10181.9 RLN94152.1 - 0.14 12.0 0.0 0.44 10.4 0.0 1.8 2 0 0 2 2 2 0 GPI-GlcNAc transferase complex, PIG-H component Chromo PF00385.24 RLN94153.1 - 3.4e-13 49.3 2.1 5.2e-10 39.1 0.4 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain FancD2 PF14631.6 RLN94153.1 - 6.5 4.0 7.7 0.12 9.7 0.6 1.6 2 0 0 2 2 2 0 Fanconi anaemia protein FancD2 nuclease Actin PF00022.19 RLN94154.1 - 1.1e-48 165.9 0.0 4.2e-47 160.7 0.0 2.7 1 1 0 1 1 1 1 Actin Pkinase_Tyr PF07714.17 RLN94155.1 - 5.7e-28 97.9 0.0 6.9e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN94155.1 - 6.5e-25 88.0 0.0 9e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.6 RLN94156.1 - 0.12 13.0 0.0 1 10.1 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat Pkinase_Tyr PF07714.17 RLN94157.1 - 3.7e-54 183.7 0.0 4.6e-45 153.9 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN94157.1 - 1e-46 159.4 0.0 4.7e-38 131.1 0.0 3.0 3 1 0 3 3 3 2 Protein kinase domain UBX PF00789.20 RLN94159.1 - 5.9e-15 55.2 0.1 6.4e-15 55.1 0.1 1.0 1 0 0 1 1 1 1 UBX domain BsuBI_PstI_RE_N PF17728.1 RLN94159.1 - 0.019 14.8 0.0 0.021 14.7 0.0 1.1 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease HTH domain Sua5_yciO_yrdC PF01300.18 RLN94160.1 - 1.4e-47 161.5 0.0 2.3e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 RLN94160.1 - 7.6e-18 65.4 0.2 1.1e-17 64.9 0.2 1.2 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Ras PF00071.22 RLN94161.1 - 1e-36 126.0 0.1 1.5e-36 125.4 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN94161.1 - 1.6e-26 92.9 0.1 2.8e-26 92.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN94161.1 - 2e-14 53.4 0.2 5e-14 52.1 0.1 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.10 RLN94161.1 - 1.8e-05 24.3 0.0 2.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 RLN94161.1 - 8.8e-05 22.0 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RLN94161.1 - 0.00012 22.1 0.0 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 RLN94161.1 - 0.0061 15.8 0.0 0.028 13.6 0.0 1.9 2 0 0 2 2 2 1 G-protein alpha subunit AAA_16 PF13191.6 RLN94161.1 - 0.013 15.8 0.6 0.073 13.4 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain TniB PF05621.11 RLN94161.1 - 0.026 13.9 0.0 0.099 12.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein ATP_bind_1 PF03029.17 RLN94161.1 - 0.046 13.5 0.0 0.13 12.0 0.0 1.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DivIC PF04977.15 RLN94161.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Septum formation initiator GP24_25 PF17388.2 RLN94162.1 - 0.057 13.4 0.4 0.082 12.9 0.4 1.3 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 ARID PF01388.21 RLN94163.1 - 7.7e-11 42.5 0.0 1.6e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 RLN94163.1 - 0.00031 20.1 2.5 0.084 12.2 0.0 2.8 3 0 0 3 3 3 2 SWI/SNF-like complex subunit BAF250/Osa PBP1_TM PF14812.6 RLN94163.1 - 0.27 11.7 8.0 3.1 8.2 8.5 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pex24p PF06398.11 RLN94164.1 - 7e-14 51.6 0.5 8.3e-14 51.3 0.5 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin VASt PF16016.5 RLN94164.1 - 5.8e-11 43.0 0.0 9e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain HTH_ABP1_N PF18107.1 RLN94165.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain Enterotoxin_b PF01376.18 RLN94166.1 - 0.013 15.7 0.0 5.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Heat-labile enterotoxin beta chain ORC_WH_C PF18137.1 RLN94166.1 - 0.033 14.2 0.6 0.059 13.4 0.6 1.4 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal YccJ PF13993.6 RLN94166.1 - 0.26 11.6 1.9 1.7 9.0 0.0 3.3 4 1 1 5 5 5 0 YccJ-like protein PDDEXK_9 PF08011.11 RLN94166.1 - 0.39 10.7 3.5 0.18 11.7 0.8 1.9 2 1 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Ank_4 PF13637.6 RLN94167.1 - 1.1e-21 76.8 10.5 0.0003 21.3 0.5 6.5 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN94167.1 - 1.8e-20 73.3 4.2 2.2e-06 28.2 0.0 4.2 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN94167.1 - 2.7e-15 56.2 6.9 0.15 12.4 0.1 8.5 5 3 4 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN94167.1 - 5.4e-14 50.9 3.9 8.8 7.3 0.0 9.2 9 0 0 9 9 9 3 Ankyrin repeat CNOT1_HEAT PF16418.5 RLN94167.1 - 0.037 14.1 1.1 0.99 9.5 0.1 3.5 3 1 1 4 4 4 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Ank PF00023.30 RLN94167.1 - 0.12 12.8 0.9 53 4.5 0.3 4.8 3 1 0 3 3 3 0 Ankyrin repeat bZIP_1 PF00170.21 RLN94168.1 - 3.2e-07 30.4 0.4 5.5e-07 29.6 0.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RLN94168.1 - 1.5e-06 28.2 2.3 2.2e-06 27.6 1.6 1.6 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 RLN94168.1 - 1.9e-05 25.1 1.1 3e-05 24.4 1.1 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF1465 PF07323.12 RLN94168.1 - 0.0076 16.1 0.3 0.011 15.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1465) Transglut_core PF01841.19 RLN94169.1 - 7.7e-12 45.7 0.3 1.8e-11 44.4 0.3 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 RLN94169.1 - 6.3e-11 42.2 1.5 1.2e-10 41.2 1.5 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Laminin_G_3 PF13385.6 RLN94169.1 - 0.00035 20.8 0.0 0.00082 19.5 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Zn_Tnp_IS1595 PF12760.7 RLN94169.1 - 0.29 11.1 5.4 0.058 13.4 0.7 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Polyketide_cyc PF03364.20 RLN94170.1 - 2e-17 63.6 0.2 4e-17 62.7 0.2 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Lactonase PF10282.9 RLN94170.1 - 4.4e-16 59.1 0.1 7.3e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller EF-hand_1 PF00036.32 RLN94170.1 - 4.9e-10 38.2 0.1 0.00038 19.8 0.0 3.1 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 RLN94170.1 - 2.4e-06 26.8 0.2 0.00033 20.0 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RLN94170.1 - 2.7e-06 26.8 0.6 0.0076 16.1 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 RLN94170.1 - 6.7e-06 26.5 2.9 6.7e-05 23.3 1.1 3.0 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.6 RLN94170.1 - 3e-05 23.8 0.4 0.014 15.3 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain pair Polyketide_cyc2 PF10604.9 RLN94170.1 - 6.7e-05 23.2 0.1 0.00016 21.9 0.1 1.6 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport TetR_C_15 PF17918.1 RLN94171.1 - 1 10.2 6.7 1.3 9.8 4.4 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HMA PF00403.26 RLN94172.1 - 0.017 15.6 0.8 0.017 15.6 0.8 3.5 4 0 0 4 4 4 0 Heavy-metal-associated domain RhgB_N PF09284.10 RLN94173.1 - 2.3e-96 322.2 2.2 3.4e-96 321.6 2.2 1.3 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 RLN94173.1 - 7.3e-39 133.3 0.0 2.1e-38 131.8 0.0 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 RLN94173.1 - 1.2e-19 69.8 8.1 2e-16 59.5 2.6 4.3 4 0 0 4 4 4 2 Polysaccharide lyase family 4, domain II DUF4646 PF15496.6 RLN94173.1 - 0.15 12.6 0.0 0.52 10.9 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) Acyl-CoA_dh_2 PF08028.11 RLN94173.1 - 0.76 10.0 3.4 0.46 10.8 0.5 2.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain bZIP_2 PF07716.15 RLN94175.1 - 1.5e-06 28.2 0.3 2.8e-06 27.3 0.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 RLN94175.1 - 1.3e-05 25.2 0.3 2.6e-05 24.2 0.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 RLN94175.1 - 5.7e-05 23.6 0.6 0.00011 22.6 0.6 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 RLN94176.1 - 7e-05 22.8 0.6 0.00016 21.7 0.6 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 RLN94176.1 - 0.0041 17.2 2.0 0.0041 17.2 2.0 1.6 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 RLN94176.1 - 0.0074 16.8 2.1 0.015 15.8 2.1 1.5 1 1 0 1 1 1 1 bZIP Maf transcription factor DUF3435 PF11917.8 RLN94177.1 - 0.07 12.0 1.7 0.091 11.7 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) bPH_6 PF10756.9 RLN94177.1 - 0.14 12.3 0.2 0.21 11.7 0.2 1.2 1 0 0 1 1 1 0 Bacterial PH domain RVT_thumb PF06817.14 RLN94177.1 - 0.17 11.7 0.7 29 4.6 0.1 3.1 3 0 0 3 3 3 0 Reverse transcriptase thumb domain RhgB_N PF09284.10 RLN94178.1 - 2e-99 332.2 3.5 3.1e-99 331.6 3.5 1.3 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 RLN94178.1 - 5.2e-39 133.8 0.3 1.4e-38 132.4 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 RLN94178.1 - 1.9e-17 62.8 3.8 2.9e-17 62.2 0.9 2.7 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II AAA PF00004.29 RLN94179.1 - 1.8e-53 180.5 6.8 8.9e-14 52.0 0.0 5.2 5 0 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 RLN94179.1 - 3.8e-30 105.0 0.0 1.1e-29 103.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_lid_6 PF17866.1 RLN94179.1 - 4e-24 84.6 6.8 1.1e-05 25.5 0.2 5.6 5 0 0 5 5 4 4 AAA lid domain RuvB_N PF05496.12 RLN94179.1 - 5.1e-15 55.6 0.9 0.0065 16.2 0.0 4.6 4 0 0 4 4 4 3 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 RLN94179.1 - 1.5e-14 54.4 15.4 1e-06 28.7 0.0 6.7 6 0 0 6 6 6 1 AAA domain AAA_22 PF13401.6 RLN94179.1 - 2.5e-14 53.7 15.1 0.046 14.0 0.0 10.3 7 4 1 8 8 6 3 AAA domain AAA_5 PF07728.14 RLN94179.1 - 3.4e-13 49.8 4.6 0.035 14.1 0.0 4.9 4 0 0 4 4 4 4 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 RLN94179.1 - 1.2e-12 48.0 1.0 0.14 11.8 0.1 5.8 5 0 0 5 5 5 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 RLN94179.1 - 6.8e-12 45.5 18.3 0.0047 16.7 0.7 6.2 6 0 0 6 6 5 4 AAA domain Mg_chelatase PF01078.21 RLN94179.1 - 7.7e-12 45.0 6.2 0.12 11.7 0.1 7.0 4 3 3 7 7 7 3 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 RLN94179.1 - 9.7e-12 45.6 1.9 0.074 13.6 0.0 5.2 4 0 0 4 4 4 3 AAA domain AAA_19 PF13245.6 RLN94179.1 - 3.3e-10 40.5 3.5 1.2 9.5 0.0 6.7 5 1 0 6 6 6 2 AAA domain AAA_16 PF13191.6 RLN94179.1 - 1.5e-09 38.4 12.8 0.11 12.9 0.0 6.4 4 1 1 5 5 5 3 AAA ATPase domain AAA_33 PF13671.6 RLN94179.1 - 6.6e-09 36.1 4.3 0.32 11.1 0.1 4.9 4 0 0 4 4 4 2 AAA domain RNA_helicase PF00910.22 RLN94179.1 - 2.8e-08 34.1 0.4 3 8.3 0.0 4.9 4 0 0 4 4 4 2 RNA helicase MCM PF00493.23 RLN94179.1 - 9.3e-07 28.2 2.5 0.0011 18.1 0.0 4.1 4 0 0 4 4 4 1 MCM P-loop domain AAA_2 PF07724.14 RLN94179.1 - 3.8e-06 27.1 7.0 0.21 11.7 0.0 4.6 5 0 0 5 5 3 2 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 RLN94179.1 - 5.4e-06 26.2 16.3 1 9.1 0.2 6.9 4 4 0 4 4 4 1 Sigma-54 interaction domain TniB PF05621.11 RLN94179.1 - 1e-05 25.0 0.0 4.2 6.7 0.0 5.3 5 1 1 6 6 5 0 Bacterial TniB protein AAA_24 PF13479.6 RLN94179.1 - 1.8e-05 24.6 1.1 5.5 6.7 0.0 4.9 4 0 0 4 4 4 0 AAA domain AAA_3 PF07726.11 RLN94179.1 - 0.0001 22.1 0.4 5.2 6.9 0.0 4.1 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 RLN94179.1 - 0.00018 21.5 1.7 13 5.8 0.0 4.3 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Torsin PF06309.11 RLN94179.1 - 0.00032 20.8 0.3 7.1 6.7 0.0 3.9 3 0 0 3 3 3 0 Torsin AAA_7 PF12775.7 RLN94179.1 - 0.00032 20.3 4.6 2.2 7.7 0.1 4.3 4 0 0 4 4 4 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 RLN94179.1 - 0.00052 19.8 1.6 9.2 6.0 0.0 4.4 4 0 0 4 4 4 0 IstB-like ATP binding protein NTPase_1 PF03266.15 RLN94179.1 - 0.00094 19.1 5.0 10 6.0 0.1 4.5 4 0 0 4 4 4 0 NTPase AAA_28 PF13521.6 RLN94179.1 - 0.0013 19.0 15.3 2.6 8.3 0.0 5.6 5 0 0 5 5 4 2 AAA domain NACHT PF05729.12 RLN94179.1 - 0.0026 17.7 2.2 5.4 6.9 0.0 4.4 4 0 0 4 4 4 0 NACHT domain ABC_tran PF00005.27 RLN94179.1 - 0.0028 18.2 11.7 11 6.5 0.0 5.6 5 0 0 5 5 5 0 ABC transporter APS_kinase PF01583.20 RLN94179.1 - 0.0042 17.0 2.5 11 5.9 0.0 4.0 4 0 0 4 4 3 0 Adenylylsulphate kinase PRK PF00485.18 RLN94179.1 - 0.0061 16.3 1.8 12 5.6 0.0 3.7 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.18 RLN94179.1 - 0.013 14.9 0.1 48 3.2 0.0 4.2 4 0 0 4 4 4 0 FtsK/SpoIIIE family CbiA PF01656.23 RLN94179.1 - 0.021 14.9 5.9 5.9 7.0 0.0 4.6 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain Parvo_NS1 PF01057.17 RLN94179.1 - 0.023 13.8 0.7 7.2 5.6 0.0 3.5 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 DnaJ-X PF14308.6 RLN94179.1 - 0.047 13.1 6.8 0.13 11.6 0.0 2.9 3 0 0 3 3 2 0 X-domain of DnaJ-containing TrwB_AAD_bind PF10412.9 RLN94179.1 - 0.054 12.4 4.7 1.8 7.4 0.2 3.9 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain CPSase_sm_chain PF00988.22 RLN94179.1 - 0.07 13.0 0.2 18 5.2 0.0 3.2 3 0 0 3 3 2 0 Carbamoyl-phosphate synthase small chain, CPSase domain UvrD_C_2 PF13538.6 RLN94179.1 - 0.11 12.3 0.0 0.61 10.0 0.0 2.2 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Transposase_20 PF02371.16 RLN94179.1 - 0.12 12.8 0.5 16 5.9 0.0 3.6 4 0 0 4 4 3 0 Transposase IS116/IS110/IS902 family KTI12 PF08433.10 RLN94179.1 - 0.22 10.9 7.3 15 5.0 0.1 4.4 5 0 0 5 5 5 0 Chromatin associated protein KTI12 DUF3987 PF13148.6 RLN94179.1 - 0.51 9.3 0.0 0.51 9.3 0.0 6.1 7 0 0 7 7 5 0 Protein of unknown function (DUF3987) PhoH PF02562.16 RLN94179.1 - 0.58 9.6 10.9 3.7 7.0 0.3 4.6 4 0 0 4 4 4 0 PhoH-like protein zf-TRM13_CCCH PF11722.8 RLN94179.1 - 2.4 8.0 9.8 0.19 11.5 0.2 3.7 3 0 0 3 3 2 0 CCCH zinc finger in TRM13 protein Mur_ligase_M PF08245.12 RLN94179.1 - 4 7.4 13.4 12 5.8 0.4 4.1 4 0 0 4 4 4 0 Mur ligase middle domain ResIII PF04851.15 RLN94179.1 - 4.9 7.1 14.0 1.5 8.8 0.0 5.4 5 3 2 7 7 4 0 Type III restriction enzyme, res subunit Thymidylate_kin PF02223.17 RLN94179.1 - 5.8 6.5 10.6 32 4.1 0.2 4.4 4 0 0 4 4 3 0 Thymidylate kinase DUF2075 PF09848.9 RLN94179.1 - 10 5.3 21.8 25 4.0 0.0 6.2 6 1 0 6 6 6 0 Uncharacterized conserved protein (DUF2075) TPR_12 PF13424.6 RLN94180.1 - 1.2e-06 28.7 0.9 0.075 13.3 0.2 4.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN94180.1 - 9.5e-05 22.2 1.5 1.1 9.4 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN94180.1 - 0.00011 21.9 4.7 1.5 8.8 0.2 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 RLN94180.1 - 0.00018 21.4 2.7 5.2 7.4 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN94180.1 - 0.00022 21.7 0.1 0.028 14.9 0.1 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN94180.1 - 0.00025 21.6 0.1 1.5 9.5 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN94180.1 - 0.0005 20.7 0.7 5 8.2 0.0 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN94180.1 - 0.002 18.3 1.1 0.15 12.3 0.3 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 RLN94180.1 - 0.0086 16.2 1.2 11 6.5 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF3808 PF10300.9 RLN94180.1 - 0.011 14.5 1.5 0.088 11.5 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3808) Drf_FH3 PF06367.16 RLN94180.1 - 0.012 15.3 1.0 0.058 13.0 0.2 2.1 2 1 0 2 2 2 0 Diaphanous FH3 Domain TPR_MalT PF17874.1 RLN94180.1 - 0.018 14.4 0.2 0.028 13.8 0.2 1.3 1 0 0 1 1 1 0 MalT-like TPR region SNAP PF14938.6 RLN94180.1 - 0.033 13.6 4.2 0.035 13.5 1.5 2.0 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP MIT PF04212.18 RLN94180.1 - 0.035 14.2 3.6 0.46 10.6 0.1 2.6 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain Rubrerythrin PF02915.17 RLN94180.1 - 0.044 14.2 3.0 0.079 13.4 1.7 2.1 1 1 1 2 2 2 0 Rubrerythrin TPR_6 PF13174.6 RLN94180.1 - 0.066 13.9 1.6 3.6 8.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Dimer_Tnp_hAT PF05699.14 RLN94181.1 - 3.3e-10 39.6 0.0 6.1e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region His_Phos_2 PF00328.22 RLN94184.1 - 1.3e-81 275.0 4.2 5.4e-46 157.7 2.3 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 RLN94184.1 - 7.2e-33 112.6 0.0 1.7e-32 111.4 0.0 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 RLN94184.1 - 2.5e-06 27.2 0.0 4.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain His_Phos_1 PF00300.22 RLN94184.1 - 0.034 13.9 0.1 1.3 8.7 0.1 3.3 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) SWIRM-assoc_1 PF16495.5 RLN94184.1 - 1.7 8.7 12.8 2 8.4 1.8 2.6 2 0 0 2 2 2 0 SWIRM-associated region 1 Ank_2 PF12796.7 RLN94186.1 - 6.9e-34 116.3 10.3 1.1e-12 48.4 0.3 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN94186.1 - 2.5e-25 88.5 4.6 1.6e-09 38.1 0.5 4.7 2 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN94186.1 - 6e-24 83.4 15.7 5.1e-05 23.5 0.2 6.4 6 1 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 RLN94186.1 - 7.9e-21 73.9 12.5 2.3e-07 30.9 0.1 5.8 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN94186.1 - 1.9e-19 67.7 6.9 0.0037 17.6 0.0 7.4 8 0 0 8 8 8 5 Ankyrin repeat Imm_superinfect PF14373.6 RLN94186.1 - 0.016 15.1 0.3 3.8 7.5 0.0 3.3 3 0 0 3 3 3 0 Superinfection immunity protein PEGA PF08308.11 RLN94186.1 - 0.033 14.1 0.0 0.36 10.7 0.0 2.4 3 0 0 3 3 3 0 PEGA domain Dus PF01207.17 RLN94187.1 - 5.1e-30 104.6 0.0 1e-28 100.4 0.0 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) PAP_assoc PF03828.19 RLN94188.1 - 6.7e-13 48.6 0.0 1.8e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 RLN94188.1 - 0.0011 19.2 0.0 0.017 15.4 0.0 2.5 1 1 0 1 1 1 1 Nucleotidyltransferase domain TPT PF03151.16 RLN94192.1 - 6.2e-58 196.4 21.4 7.3e-58 196.2 21.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 RLN94192.1 - 8.7e-11 42.1 26.3 3e-06 27.4 9.9 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 RLN94192.1 - 2.3e-07 30.3 21.2 5.9e-07 29.0 21.2 1.9 1 1 0 1 1 1 1 UAA transporter family HeLo PF14479.6 RLN94192.1 - 0.24 11.2 0.1 0.39 10.5 0.1 1.2 1 0 0 1 1 1 0 Prion-inhibition and propagation TMEM234 PF10639.9 RLN94192.1 - 1 9.4 12.4 0.82 9.7 1.7 3.3 3 0 0 3 3 3 0 Putative transmembrane family 234 LZ_Tnp_IS66 PF13007.7 RLN94193.1 - 0.42 11.4 10.2 0.9 10.4 4.3 2.5 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain NARP1 PF12569.8 RLN94193.1 - 0.79 8.6 4.0 1.3 7.9 4.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SPT6_acidic PF14632.6 RLN94193.1 - 2.4 8.8 9.1 4.7 7.9 1.5 2.6 2 1 0 2 2 2 0 Acidic N-terminal SPT6 UQ_con PF00179.26 RLN94194.1 - 2.9e-14 52.9 0.0 3.4e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RFC1 PF08519.12 RLN94195.1 - 1.2e-15 58.1 0.0 1.9e-09 37.9 0.0 2.3 2 0 0 2 2 2 2 Replication factor RFC1 C terminal domain Biotin_carb_N PF00289.22 RLN94196.1 - 4.1e-28 98.1 1.5 4.4e-28 98.0 0.1 1.7 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain GxGYxYP_N PF16216.5 RLN94196.1 - 0.0095 16.1 0.0 0.012 15.8 0.0 1.1 1 0 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function N-terminal ZT_dimer PF16916.5 RLN94197.1 - 1.5e-10 41.0 1.3 2.8e-10 40.2 1.3 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Cation_efflux PF01545.21 RLN94197.1 - 1.5e-05 24.8 0.5 2e-05 24.4 0.5 1.1 1 0 0 1 1 1 1 Cation efflux family Halogen_Hydrol PF10112.9 RLN94198.1 - 0.064 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF2062 PF09835.9 RLN94199.1 - 9.5 6.1 20.7 2.6e+02 1.4 20.9 2.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Longin PF13774.6 RLN94200.1 - 4.3e-24 84.3 0.0 6.5e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 RLN94200.1 - 7e-16 57.8 0.3 1e-15 57.2 0.3 1.3 1 0 0 1 1 1 1 Synaptobrevin COQ9 PF08511.11 RLN94200.1 - 0.024 14.4 0.0 0.095 12.5 0.0 2.0 2 0 0 2 2 2 0 COQ9 ZapB PF06005.12 RLN94201.1 - 0.00057 20.3 2.0 0.0013 19.2 2.0 1.6 1 0 0 1 1 1 1 Cell division protein ZapB HALZ PF02183.18 RLN94201.1 - 0.00098 19.3 1.9 0.0025 18.0 0.9 2.2 2 0 0 2 2 2 1 Homeobox associated leucine zipper DHR10 PF18595.1 RLN94201.1 - 0.0099 15.9 3.1 0.019 15.1 3.1 1.4 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain Cep57_CLD_2 PF14197.6 RLN94201.1 - 0.02 15.0 1.2 0.08 13.0 1.2 2.0 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 bZIP_1 PF00170.21 RLN94201.1 - 0.031 14.4 0.5 0.031 14.4 0.5 2.2 2 0 0 2 2 2 0 bZIP transcription factor YabA PF06156.13 RLN94201.1 - 0.066 13.8 0.2 0.15 12.7 0.2 1.7 1 0 0 1 1 1 0 Initiation control protein YabA DUF3450 PF11932.8 RLN94201.1 - 0.088 12.1 1.6 0.13 11.5 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MctB PF11382.8 RLN94201.1 - 0.089 12.5 1.1 0.17 11.6 1.1 1.4 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB SDF PF00375.18 RLN94202.1 - 7.8e-69 232.6 37.2 2e-68 231.2 37.2 1.6 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family Fascin PF06268.13 RLN94202.1 - 0.001 19.3 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 Fascin domain Proteasome PF00227.26 RLN94203.1 - 7e-30 103.9 0.0 1.2e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit DLIC PF05783.11 RLN94203.1 - 1.7e-05 23.9 0.0 0.00085 18.3 0.0 2.2 1 1 0 2 2 2 1 Dynein light intermediate chain (DLIC) Roc PF08477.13 RLN94203.1 - 0.0014 18.8 0.0 0.0036 17.5 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RLN94203.1 - 0.0026 17.4 0.0 0.058 13.0 0.0 2.4 2 0 0 2 2 2 1 Ras family RsgA_GTPase PF03193.16 RLN94203.1 - 0.0083 16.0 0.0 0.064 13.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 RLN94203.1 - 0.02 15.2 0.0 0.045 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 RLN94203.1 - 0.067 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN94203.1 - 0.14 12.4 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Glyco_transf_36 PF06165.11 RLN94204.1 - 0.018 14.5 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 36 DUF4644 PF15486.6 RLN94204.1 - 0.024 14.4 0.1 0.049 13.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) TAD2 PF18521.1 RLN94204.1 - 0.053 13.5 0.3 0.11 12.6 0.3 1.5 1 0 0 1 1 1 0 Transactivation domain 2 SnoaL PF07366.12 RLN94205.1 - 0.00037 20.3 0.0 0.00066 19.5 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 RLN94205.1 - 0.0028 18.3 0.0 0.0049 17.5 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain bZIP_1 PF00170.21 RLN94205.1 - 0.0037 17.3 2.7 0.0076 16.3 2.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor TMCO5 PF14992.6 RLN94205.1 - 0.097 12.2 0.7 0.12 11.9 0.7 1.2 1 0 0 1 1 1 0 TMCO5 family SAS4 PF15460.6 RLN94205.1 - 0.13 12.4 2.3 0.27 11.4 2.3 1.5 1 1 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 bZIP_2 PF07716.15 RLN94205.1 - 1 9.5 6.3 2.2 8.4 6.3 1.6 1 0 0 1 1 1 0 Basic region leucine zipper DivIVA PF05103.13 RLN94206.1 - 0.018 15.1 9.6 0.018 15.1 9.6 3.2 1 1 1 3 3 3 0 DivIVA protein Mitofilin PF09731.9 RLN94206.1 - 0.42 9.4 31.6 0.37 9.6 19.0 2.1 1 1 1 2 2 2 0 Mitochondrial inner membrane protein DUF948 PF06103.11 RLN94206.1 - 1.4 9.2 11.2 3.3e+02 1.6 11.2 3.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) V-ATPase_G_2 PF16999.5 RLN94206.1 - 1.8 9.0 54.0 8.2 6.9 16.1 3.4 1 1 2 3 3 3 0 Vacuolar (H+)-ATPase G subunit Kinesin_assoc PF16183.5 RLN94206.1 - 4.2 7.5 11.2 7.9 6.6 11.2 1.5 1 0 0 1 1 1 0 Kinesin-associated DUF1664 PF07889.12 RLN94206.1 - 7.5 6.6 6.7 6.6 6.8 4.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PRKCSH PF07915.13 RLN94207.1 - 8.2e-19 68.4 0.0 1e-13 52.1 0.1 2.5 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 RLN94207.1 - 3.4e-07 30.1 0.0 8.6e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Sad1_UNC PF07738.13 RLN94207.1 - 0.12 12.4 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Stathmin PF00836.19 RLN94207.1 - 0.13 12.2 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 Stathmin family Cupin_8 PF13621.6 RLN94208.1 - 2.7e-38 132.1 0.1 1.1e-32 113.8 0.1 2.1 1 1 1 2 2 2 2 Cupin-like domain Cupin_4 PF08007.12 RLN94208.1 - 1.1e-12 48.0 0.1 2e-12 47.2 0.1 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 RLN94208.1 - 0.0019 18.6 0.0 0.0053 17.2 0.0 1.8 3 0 0 3 3 3 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 RLN94208.1 - 0.025 14.3 0.0 0.082 12.6 0.0 1.8 2 0 0 2 2 2 0 Cupin domain ABC2_membrane PF01061.24 RLN94209.1 - 2.5e-27 95.7 17.2 3.3e-27 95.3 17.2 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN94209.1 - 1.3e-20 74.3 0.0 3.6e-20 72.9 0.0 1.8 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 RLN94209.1 - 0.00055 19.8 0.0 0.12 12.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN94209.1 - 0.0016 18.1 0.4 0.0047 16.6 0.4 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN94209.1 - 0.003 17.9 0.0 0.017 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 RLN94209.1 - 0.0092 15.4 0.0 3.8 6.9 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 RLN94209.1 - 0.019 13.8 0.5 0.038 12.8 0.5 1.5 1 1 0 1 1 1 0 Predicted ATPase of the ABC class AAA_25 PF13481.6 RLN94209.1 - 0.032 13.8 0.0 0.073 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 RLN94209.1 - 0.032 13.6 0.1 0.077 12.3 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 RLN94209.1 - 0.035 14.5 1.7 0.039 14.3 0.4 2.0 2 1 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.18 RLN94209.1 - 0.039 13.7 0.0 0.76 9.5 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 RLN94209.1 - 0.051 13.7 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase MeaB PF03308.16 RLN94209.1 - 0.08 11.9 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 RLN94209.1 - 0.098 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RLN94209.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 RLN94209.1 - 0.13 12.0 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RLN94209.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 RLN94209.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ABC2_membrane_3 PF12698.7 RLN94209.1 - 7.6 5.5 16.6 2.4 7.2 13.3 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein PA28_beta PF02252.18 RLN94210.1 - 8.3e-29 100.1 0.0 4.1e-18 65.5 0.0 2.2 2 0 0 2 2 2 2 Proteasome activator pa28 beta subunit Mur_ligase_M PF08245.12 RLN94211.1 - 1.7e-09 37.9 0.0 2.9e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 RLN94211.1 - 6.6e-06 26.3 0.3 7e-05 23.0 0.0 2.6 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain EF-hand_1 PF00036.32 RLN94212.1 - 0.0029 17.1 0.0 0.01 15.3 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 RLN94212.1 - 0.0037 17.7 0.1 0.017 15.5 0.1 2.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN94212.1 - 0.0058 16.1 0.1 0.023 14.2 0.1 2.1 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 RLN94212.1 - 0.057 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 RLN94212.1 - 0.084 12.8 0.0 0.39 10.8 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain EF-hand_4 PF12763.7 RLN94212.1 - 0.086 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand HyaE PF07449.11 RLN94212.1 - 0.11 12.4 0.4 0.49 10.4 0.0 2.1 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE DUF4611 PF15387.6 RLN94212.1 - 0.35 11.1 3.9 1 9.7 3.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.6 RLN94213.1 - 7.5 7.0 13.8 0.45 10.9 3.8 3.1 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PC4 PF02229.16 RLN94216.1 - 7.9e-41 137.5 0.1 8.7e-21 73.3 0.1 2.3 2 0 0 2 2 2 2 Transcriptional Coactivator p15 (PC4) L27_1 PF09058.10 RLN94216.1 - 0.62 10.1 2.5 14 5.8 0.1 2.7 3 0 0 3 3 3 0 L27_1 SRF-TF PF00319.18 RLN94217.1 - 1.5e-24 85.2 0.2 2.8e-24 84.3 0.2 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Macoilin PF09726.9 RLN94218.1 - 0.74 8.3 4.7 0.87 8.1 4.7 1.0 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 RLN94218.1 - 0.95 6.5 3.4 1.1 6.3 3.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Mucin PF01456.17 RLN94218.1 - 9.3 6.2 16.4 22 5.1 16.4 1.8 1 1 0 1 1 1 0 Mucin-like glycoprotein GatB_N PF02934.15 RLN94219.1 - 1.1e-100 336.5 0.0 3e-100 335.1 0.0 1.6 1 1 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 RLN94219.1 - 2.3e-37 128.2 0.1 4.2e-37 127.3 0.1 1.5 1 0 0 1 1 1 1 GatB domain Abhydrolase_6 PF12697.7 RLN94220.1 - 1.8e-10 41.8 0.0 2.1e-10 41.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN94220.1 - 2e-05 24.0 0.0 3e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN94220.1 - 0.05 13.2 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold EF-hand_7 PF13499.6 RLN94223.1 - 1e-05 25.9 0.8 0.00014 22.2 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN94223.1 - 0.0022 17.4 0.1 3.4 7.4 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RLN94223.1 - 0.0029 17.4 0.0 1.9 8.6 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 RLN94223.1 - 0.055 13.3 0.1 0.76 9.7 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain pair Sial-lect-inser PF09264.10 RLN94224.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Vibrio cholerae sialidase, lectin insertion RabGAP-TBC PF00566.18 RLN94225.1 - 1.6e-38 132.5 0.0 2.2e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Retinal PF15449.6 RLN94225.1 - 2.9 5.6 6.8 4.1 5.1 6.8 1.1 1 0 0 1 1 1 0 Retinal protein Elicitin PF00964.17 RLN94226.1 - 3.5e-15 55.9 2.2 7.3e-15 54.8 2.2 1.6 1 0 0 1 1 1 1 Elicitin ERM PF00769.19 RLN94226.1 - 0.064 13.1 39.2 0.045 13.5 17.6 2.4 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF743 PF05332.11 RLN94226.1 - 0.58 10.2 6.0 0.069 13.2 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF743) Elicitin PF00964.17 RLN94227.1 - 5.4e-19 68.1 1.5 9.2e-19 67.3 1.5 1.4 1 0 0 1 1 1 1 Elicitin Coa1 PF08695.10 RLN94227.1 - 0.017 14.8 0.0 0.052 13.3 0.0 1.7 1 1 1 2 2 2 0 Cytochrome oxidase complex assembly protein 1 CNDH2_C PF16858.5 RLN94228.1 - 0.00025 21.0 0.6 0.00058 19.8 0.4 1.7 1 1 1 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term Myosin_head PF00063.21 RLN94229.1 - 6.6e-213 708.7 0.0 1.4e-212 707.6 0.0 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_30 PF13604.6 RLN94229.1 - 0.00029 20.6 0.1 0.00077 19.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 RLN94229.1 - 0.0048 16.0 0.2 0.011 14.9 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 RLN94229.1 - 0.0081 16.4 0.0 0.03 14.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RLN94229.1 - 0.013 15.9 0.0 0.058 13.8 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 RLN94229.1 - 0.017 15.4 0.0 0.059 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 RLN94229.1 - 0.035 13.5 0.0 0.082 12.2 0.0 1.5 1 0 0 1 1 1 0 KaiC PH PF00169.29 RLN94230.1 - 0.0014 19.1 0.1 0.0035 17.8 0.0 1.7 2 0 0 2 2 2 1 PH domain Frankia_peptide PF14407.6 RLN94230.1 - 0.11 12.4 0.0 0.39 10.7 0.0 1.9 1 1 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. CHZ PF09649.10 RLN94230.1 - 0.22 11.0 1.6 0.41 10.2 1.6 1.5 1 0 0 1 1 1 0 Histone chaperone domain CHZ HTH_23 PF13384.6 RLN94232.1 - 0.001 18.8 0.2 1.6 8.6 0.0 2.9 3 0 0 3 3 3 2 Homeodomain-like domain HTH_IclR PF09339.10 RLN94232.1 - 0.0051 16.6 1.3 0.077 12.8 0.2 2.5 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_30 PF13556.6 RLN94232.1 - 0.02 14.7 1.9 0.35 10.7 0.6 2.6 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 RLN94232.1 - 0.027 14.7 0.2 0.083 13.1 0.2 1.9 1 0 0 1 1 1 0 Transposase HTH_28 PF13518.6 RLN94232.1 - 0.032 14.4 0.2 6.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 RLN94233.1 - 0.00043 20.4 0.3 0.031 14.4 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 RLN94233.1 - 0.025 14.4 0.1 1 9.2 0.1 2.5 2 0 0 2 2 2 0 Homeodomain-like domain TFIIB PF00382.19 RLN94234.1 - 3.7e-24 84.6 0.6 2.3e-11 43.6 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat NAD_binding_4 PF07993.12 RLN94234.1 - 0.06 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein DPM3 PF08285.11 RLN94235.1 - 7.5e-27 93.4 1.8 8.3e-27 93.2 1.8 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Solute_trans_a PF03619.16 RLN94235.1 - 0.0092 15.5 0.4 0.012 15.2 0.4 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha CTP_transf_like PF01467.26 RLN94236.1 - 3.6e-25 88.8 0.0 9.9e-25 87.4 0.0 1.8 1 0 0 1 1 1 1 Cytidylyltransferase-like Arm PF00514.23 RLN94236.1 - 2.3e-05 24.3 7.8 2.2 8.5 0.1 6.3 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 RLN94236.1 - 2.5e-05 24.2 3.7 2.2 8.4 0.2 4.8 3 1 1 4 4 4 2 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_N PF03224.14 RLN94236.1 - 0.0033 16.8 6.6 0.016 14.5 0.4 2.8 1 1 2 3 3 3 1 V-ATPase subunit H CDC14 PF08045.11 RLN94236.1 - 0.015 14.4 0.9 0.072 12.2 0.1 2.3 2 1 1 3 3 3 0 Cell division control protein 14, SIN component DUF3361 PF11841.8 RLN94236.1 - 0.04 13.8 5.4 0.17 11.8 0.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3361) DUF2722 PF10846.8 RLN94236.1 - 0.18 10.7 1.0 0.28 10.1 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4704 PF15787.5 RLN94236.1 - 0.33 10.1 2.6 0.22 10.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4704) UQ_con PF00179.26 RLN94237.1 - 6.2e-24 84.2 0.0 1.5e-18 66.8 0.1 2.0 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme CTP_transf_like PF01467.26 RLN94238.1 - 7.5e-26 91.0 0.0 1.5e-25 90.1 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like Rgp1 PF08737.10 RLN94239.1 - 6.5e-23 81.6 0.0 2.8e-14 53.1 0.0 3.1 3 1 0 3 3 3 2 Rgp1 Arrestin_C PF02752.22 RLN94239.1 - 0.0012 19.3 0.0 0.36 11.3 0.0 2.9 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 RLN94239.1 - 0.17 11.9 0.4 1 9.4 0.1 2.2 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Pinin_SDK_memA PF04696.13 RLN94240.1 - 2.2e-25 89.2 13.6 2.2e-25 89.2 13.6 4.0 4 2 1 5 5 5 1 pinin/SDK/memA/ protein conserved region SAP PF02037.27 RLN94240.1 - 2e-11 43.4 3.8 2e-11 43.4 3.8 2.3 2 0 0 2 2 2 1 SAP domain Fib_alpha PF08702.10 RLN94240.1 - 0.042 14.0 1.1 0.042 14.0 1.1 3.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family B9-C2 PF07162.11 RLN94241.1 - 8.1e-37 127.0 0.0 1e-36 126.7 0.0 1.1 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein CH PF00307.31 RLN94243.1 - 0.00045 20.4 0.0 0.00056 20.1 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Ost5 PF05251.12 RLN94244.1 - 3.8e-18 65.5 7.2 6e-18 64.9 6.1 2.0 2 0 0 2 2 2 1 Oligosaccharyltransferase subunit 5 CLASP_N PF12348.8 RLN94244.1 - 0.00027 20.6 0.5 0.003 17.1 0.1 2.3 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.22 RLN94244.1 - 0.01 16.0 0.8 4.7 7.7 0.0 4.8 4 0 0 4 4 4 0 HEAT repeat AF-4 PF05110.13 RLN94244.1 - 1.8 6.6 6.8 3 5.8 6.8 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein AMPK1_CBM PF16561.5 RLN94245.1 - 1.5e-32 111.7 0.5 2.6e-32 110.9 0.5 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 RLN94245.1 - 2.1e-25 88.8 1.6 2.1e-25 88.8 1.6 1.7 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain DUF4054 PF13262.6 RLN94246.1 - 0.88 9.6 3.1 3.5 7.7 0.1 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF4054) DUF3951 PF13131.6 RLN94247.1 - 0.08 13.1 0.1 0.28 11.4 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) RskA PF10099.9 RLN94247.1 - 0.1 12.9 2.1 27 5.0 0.0 3.1 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Carb_anhydrase PF00194.21 RLN94248.1 - 2.8e-41 141.7 0.0 4.3e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase OrfB_Zn_ribbon PF07282.11 RLN94249.1 - 2.8e-05 24.0 3.2 0.088 12.7 0.1 2.2 2 0 0 2 2 2 2 Putative transposase DNA-binding domain CCT PF06203.14 RLN94255.1 - 5.5e-15 55.1 12.5 8.6e-15 54.5 12.5 1.3 1 0 0 1 1 1 1 CCT motif ABC_trans_N PF14510.6 RLN94257.1 - 0.2 12.3 5.2 0.35 11.5 0.2 2.9 3 0 0 3 3 3 0 ABC-transporter N-terminal CALM_bind PF16025.5 RLN94257.1 - 3.6 8.1 10.1 2.1 8.9 4.6 2.6 2 1 0 2 2 2 0 Calcium-dependent calmodulin binding Med10 PF09748.9 RLN94260.1 - 4.2e-08 33.2 0.0 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 2 Transcription factor subunit Med10 of Mediator complex Peptidase_M8 PF01457.16 RLN94261.1 - 1.3e-63 215.5 13.9 1.9e-47 162.1 8.0 2.8 3 0 0 3 3 3 2 Leishmanolysin ADAM17_MPD PF16698.5 RLN94261.1 - 2.1 8.8 11.1 2.4 8.6 4.6 2.7 2 0 0 2 2 2 0 Membrane-proximal domain, switch, for ADAM17 PHO4 PF01384.20 RLN94262.1 - 1.4e-95 320.2 19.9 1.8e-95 319.9 19.9 1.1 1 0 0 1 1 1 1 Phosphate transporter family Dsl1_N PF11988.8 RLN94264.1 - 0.14 11.1 3.1 0.095 11.7 1.5 1.4 2 0 0 2 2 2 0 Retrograde transport protein Dsl1 N terminal T2SSppdC PF12528.8 RLN94264.1 - 0.72 10.7 5.9 0.75 10.6 4.2 2.0 2 0 0 2 2 2 0 Type II secretion prepilin peptidase dependent protein C Uso1_p115_C PF04871.13 RLN94265.1 - 0.11 12.9 9.6 0.033 14.6 5.0 2.3 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Pkinase_C PF00433.24 RLN94270.1 - 8.2e-07 29.6 0.2 1.7e-06 28.6 0.2 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain ZZ PF00569.17 RLN94271.1 - 5.5e-11 42.1 7.4 1.4e-10 40.8 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type F-box-like PF12937.7 RLN94271.1 - 1e-08 35.0 0.9 1e-08 35.0 0.9 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RLN94271.1 - 0.00072 19.4 0.1 0.0017 18.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain USP7_ICP0_bdg PF12436.8 RLN94271.1 - 0.0086 15.4 0.0 0.048 13.0 0.0 1.9 1 1 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 Nipped-B_C PF12830.7 RLN94273.1 - 4e-39 134.5 5.2 4.2e-38 131.2 0.0 3.7 4 1 0 4 4 4 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 RLN94273.1 - 0.0023 18.2 1.3 1.6 9.1 0.0 3.0 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion zf-Tim10_DDP PF02953.15 RLN94274.1 - 5.6e-14 51.5 3.5 5.6e-14 51.5 3.5 1.9 2 0 0 2 2 2 1 Tim10/DDP family zinc finger Hormone_recep PF00104.30 RLN94274.1 - 0.0075 15.9 5.5 0.0099 15.5 5.5 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Halogen_Hydrol PF10112.9 RLN94274.1 - 0.009 16.0 1.3 0.01 15.9 0.3 1.5 2 0 0 2 2 2 1 5-bromo-4-chloroindolyl phosphate hydrolysis protein KMP11 PF03037.16 RLN94274.1 - 0.096 13.5 2.4 2.1 9.2 0.5 2.2 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 SNARE PF05739.19 RLN94275.1 - 0.00015 21.7 1.3 0.0004 20.3 0.4 2.2 2 0 0 2 2 2 1 SNARE domain RICTOR_N PF14664.6 RLN94276.1 - 1.1e-88 297.8 1.3 1.7e-88 297.1 1.3 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 RLN94276.1 - 2.5e-28 97.9 0.9 1.4e-27 95.5 0.9 2.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 RLN94276.1 - 3.7e-26 91.1 0.2 3.8e-23 81.5 0.0 3.5 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.6 RLN94276.1 - 3.8e-20 72.3 2.6 3.6e-19 69.1 0.0 3.5 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_EZ PF13513.6 RLN94276.1 - 1.7e-05 25.2 3.2 0.073 13.6 0.1 4.3 3 1 1 4 4 4 3 HEAT-like repeat HEAT_2 PF13646.6 RLN94276.1 - 0.0063 16.9 8.7 0.17 12.3 0.0 5.2 5 0 0 5 5 5 1 HEAT repeats Arm PF00514.23 RLN94276.1 - 0.072 13.2 11.6 82 3.5 0.1 7.0 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Ribosomal_L4 PF00573.22 RLN94277.1 - 4.9e-63 212.3 0.0 6.9e-63 211.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family TYW3 PF02676.14 RLN94278.1 - 4.5e-49 166.7 0.0 1.2e-48 165.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase TYW3 Met_10 PF02475.16 RLN94278.1 - 9.3e-26 90.8 0.0 2.3e-25 89.5 0.0 1.7 1 0 0 1 1 1 1 Met-10+ like-protein Kelch_4 PF13418.6 RLN94278.1 - 2.6e-15 56.2 2.7 0.00026 21.0 0.0 6.2 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN94278.1 - 2.7e-15 56.0 6.0 0.00096 19.1 0.1 5.4 4 1 1 5 5 5 3 Kelch motif Kelch_3 PF13415.6 RLN94278.1 - 6.9e-15 54.9 5.9 0.0038 17.5 0.0 7.0 6 1 1 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.6 RLN94278.1 - 1.5e-13 50.5 2.6 0.0017 18.6 0.0 5.7 5 1 0 5 5 4 3 Kelch motif Kelch_1 PF01344.25 RLN94278.1 - 8.6e-12 44.5 13.9 1.2e-05 24.7 0.0 6.0 5 1 1 6 6 6 3 Kelch motif Kelch_2 PF07646.15 RLN94278.1 - 0.00015 21.6 11.5 0.95 9.5 0.0 5.5 5 2 0 5 5 5 2 Kelch motif Methyltransf_25 PF13649.6 RLN94278.1 - 0.0025 18.5 0.0 0.032 14.9 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 RLN94278.1 - 0.0045 16.6 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 RLN94278.1 - 0.088 12.4 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PAP_RNA-bind PF04926.15 RLN94279.1 - 4.7e-20 71.9 0.0 2.9e-19 69.3 0.0 2.1 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain CCDC84 PF14968.6 RLN94279.1 - 0.12 12.0 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Coiled coil protein 84 ANAPC1 PF12859.7 RLN94280.1 - 8.6e-18 65.2 0.6 3.7e-17 63.1 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 RLN94280.1 - 4.5e-07 30.0 14.6 0.002 18.5 0.0 6.6 6 0 0 6 6 6 3 Proteasome/cyclosome repeat Meckelin PF09773.9 RLN94281.1 - 1.6e-123 413.5 0.4 2e-122 409.9 0.4 1.9 1 1 0 1 1 1 1 Meckelin (Transmembrane protein 67) PRKCSH_1 PF13015.6 RLN94282.1 - 4.6e-09 36.2 1.1 7.6e-09 35.4 1.1 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 RLN94282.1 - 1.5e-08 35.5 2.1 3.8e-08 34.2 2.1 1.7 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Yippee-Mis18 PF03226.14 RLN94282.1 - 0.0028 17.8 0.5 0.0053 17.0 0.0 1.8 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Epimerase PF01370.21 RLN94283.1 - 1e-45 156.1 0.3 6.6e-45 153.4 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RLN94283.1 - 3.1e-40 138.6 0.0 2e-39 136.0 0.0 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 RLN94283.1 - 6.5e-19 68.0 0.4 1.5e-18 66.8 0.4 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 RLN94283.1 - 5.8e-12 45.3 0.1 4.7e-11 42.3 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 RLN94283.1 - 6.1e-12 45.3 0.3 1.3e-10 40.9 0.3 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 RLN94283.1 - 2.1e-10 40.2 0.5 1.2e-09 37.7 0.5 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 RLN94283.1 - 4.8e-05 23.3 0.1 0.18 11.7 0.0 2.7 3 0 0 3 3 3 2 NAD(P)H-binding Epimerase PF01370.21 RLN94284.1 - 2.2e-46 158.3 0.4 2.6e-45 154.8 0.4 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RLN94284.1 - 5.5e-44 150.9 0.1 4.1e-43 148.1 0.1 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 RLN94284.1 - 3.1e-20 72.3 0.3 9.4e-20 70.8 0.3 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 RLN94284.1 - 3.7e-13 49.3 0.1 7.3e-09 35.2 0.0 2.8 3 1 0 3 3 3 2 Male sterility protein Polysacc_synt_2 PF02719.15 RLN94284.1 - 6.2e-12 45.2 2.0 5.8e-10 38.8 2.0 2.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 RLN94284.1 - 1.6e-11 43.9 0.1 1.1e-10 41.1 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 RLN94284.1 - 5.2e-06 26.5 0.1 0.0068 16.3 0.0 2.5 3 0 0 3 3 3 2 NAD(P)H-binding adh_short PF00106.25 RLN94284.1 - 0.047 13.2 1.0 5.3 6.4 0.1 2.8 3 0 0 3 3 3 0 short chain dehydrogenase PAC2 PF09754.9 RLN94284.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 PAC2 family 7tm_2 PF00002.24 RLN94285.1 - 3e-07 30.0 11.4 4.2e-07 29.5 11.4 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.17 RLN94285.1 - 3.7e-06 26.2 8.0 3.7e-06 26.2 8.0 2.0 1 1 1 2 2 2 1 Frizzled/Smoothened family membrane region ERGIC_N PF13850.6 RLN94285.1 - 0.0027 18.0 0.1 0.44 10.9 0.0 2.5 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Wzy_C PF04932.15 RLN94285.1 - 0.0072 16.0 1.5 0.2 11.3 0.2 2.2 2 0 0 2 2 2 2 O-Antigen ligase DUF679 PF05078.12 RLN94285.1 - 0.05 13.6 0.3 0.088 12.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF679) DUF3043 PF11241.8 RLN94286.1 - 0.59 10.1 7.5 2.1 8.3 7.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF4770 PF15994.5 RLN94286.1 - 1 9.6 5.5 0.44 10.8 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) NOA36 PF06524.12 RLN94286.1 - 1.7 7.9 13.1 2.8 7.2 13.1 1.4 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.10 RLN94286.1 - 8.6 5.6 19.9 11 5.2 17.0 2.0 2 0 0 2 2 2 0 BUD22 PX PF00787.24 RLN94287.1 - 1.4e-11 44.3 0.0 4.8e-11 42.6 0.0 1.8 2 0 0 2 2 2 1 PX domain CENP-B_dimeris PF09026.10 RLN94287.1 - 0.062 13.7 5.8 0.15 12.5 5.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleo_P87 PF07267.11 RLN94287.1 - 0.096 11.5 0.1 0.18 10.6 0.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 AKAP28 PF14469.6 RLN94288.1 - 1.4e-05 24.8 0.0 2.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 28 kDa A-kinase anchor EF-hand_9 PF14658.6 RLN94288.1 - 0.032 14.6 0.0 0.14 12.5 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain Nop53 PF07767.11 RLN94288.1 - 0.46 9.8 6.2 0.04 13.3 1.0 1.8 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) H_PPase PF03030.16 RLN94289.1 - 8.4e-239 794.6 31.7 9.5e-239 794.4 31.7 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase CCDC53 PF10152.9 RLN94290.1 - 7.7e-84 279.7 33.8 7.2e-12 46.0 0.1 9.8 9 1 0 9 9 9 8 Subunit CCDC53 of WASH complex FH2 PF02181.23 RLN94290.1 - 2e-24 86.4 0.2 2.3e-23 82.9 0.0 2.2 2 0 0 2 2 2 1 Formin Homology 2 Domain UBA PF00627.31 RLN94290.1 - 0.023 14.6 0.0 28 4.7 0.0 5.1 8 0 0 8 8 8 0 UBA/TS-N domain PACT_coil_coil PF10495.9 RLN94290.1 - 0.03 14.9 0.2 79 3.9 0.0 4.4 4 0 0 4 4 4 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Proton_antipo_N PF00662.20 RLN94290.1 - 0.29 11.2 2.2 2.2e+02 2.0 0.0 4.5 5 0 0 5 5 5 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus GET2 PF08690.10 RLN94290.1 - 2.6 7.6 12.2 1.1 8.9 9.1 2.0 2 0 0 2 2 2 0 GET complex subunit GET2 DUF4404 PF14357.6 RLN94290.1 - 5.7 7.6 9.1 0.48 11.1 2.9 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) CRAL_TRIO PF00650.20 RLN94291.1 - 1.1e-20 74.0 0.0 2.2e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 RLN94291.1 - 0.0038 17.4 0.0 0.01 16.0 0.0 1.7 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain IKI3 PF04762.12 RLN94292.1 - 9.8e-102 341.6 0.0 1.8e-101 340.7 0.0 1.4 1 1 1 2 2 2 1 IKI3 family Cupin_7 PF12973.7 RLN94292.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 ChrR Cupin-like domain TPR_16 PF13432.6 RLN94292.1 - 0.37 11.5 13.1 0.054 14.1 6.4 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Bystin PF05291.11 RLN94293.1 - 7.2e-52 176.5 0.0 1.1e-51 175.9 0.0 1.3 1 0 0 1 1 1 1 Bystin Rho_GDI PF02115.17 RLN94294.1 - 1.4e-30 106.5 0.0 1.8e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor TIG PF01833.24 RLN94296.1 - 6e-92 301.9 43.0 2.3e-10 40.4 0.5 14.5 13 1 0 13 13 13 12 IPT/TIG domain TIG_plexin PF17960.1 RLN94296.1 - 1.3e-20 73.2 4.5 0.063 13.3 0.0 11.1 12 0 0 12 12 12 6 TIG domain Anth_Ig PF05587.13 RLN94296.1 - 2.4e-05 24.6 0.1 0.037 14.3 0.0 5.6 6 0 0 6 6 6 1 Anthrax receptor extracellular domain POTRA_1 PF08478.10 RLN94296.1 - 0.01 16.1 0.0 0.16 12.3 0.0 3.0 3 0 0 3 3 3 0 POTRA domain, FtsQ-type Neocarzinostat PF00960.18 RLN94296.1 - 0.23 11.5 10.3 0.23 11.5 0.1 5.0 5 0 0 5 5 5 0 Neocarzinostatin family TIG PF01833.24 RLN94297.1 - 2.4e-47 158.9 21.1 1.2e-08 34.9 0.0 8.5 8 0 0 8 8 8 7 IPT/TIG domain TIG_plexin PF17960.1 RLN94297.1 - 4.2e-07 29.9 0.1 1.5 8.8 0.0 6.4 6 0 0 6 6 6 2 TIG domain Ephrin_rec_like PF07699.13 RLN94297.1 - 0.27 11.0 81.5 0.0032 17.2 5.2 11.2 8 3 3 11 11 11 0 Putative ephrin-receptor like TIG PF01833.24 RLN94298.1 - 3.9e-25 87.7 15.0 1.6e-06 28.1 0.4 6.4 5 1 0 5 5 5 4 IPT/TIG domain TIG_plexin PF17960.1 RLN94298.1 - 2.3e-05 24.3 4.2 0.17 11.9 0.0 5.2 5 0 0 5 5 5 2 TIG domain DDE_1 PF03184.19 RLN94299.1 - 1.2e-22 80.4 0.0 1.9e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN94299.1 - 3.3e-11 43.1 0.0 9.1e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 RLN94299.1 - 0.0062 16.2 2.2 0.014 15.1 1.3 2.0 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain DUF3006 PF11213.8 RLN94299.1 - 0.046 14.0 0.0 0.091 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) AGT PF11440.8 RLN94299.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 DNA alpha-glucosyltransferase Proteasome PF00227.26 RLN94301.1 - 9.9e-43 145.8 0.0 1.4e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF4586 PF15239.6 RLN94301.1 - 0.053 13.7 0.0 0.071 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4586) VWA_2 PF13519.6 RLN94302.1 - 0.0018 18.9 0.0 0.0049 17.5 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain Glyco_hydro_3_C PF01915.22 RLN94304.1 - 9e-41 140.1 0.0 1.3e-40 139.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RLN94304.1 - 7.4e-13 48.4 0.0 1.3e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.11 RLN94304.1 - 0.0044 17.3 0.1 0.0088 16.3 0.1 1.6 1 0 0 1 1 1 1 CARDB Ras PF00071.22 RLN94305.1 - 3.1e-41 140.7 1.9 9.6e-40 135.8 1.9 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RLN94305.1 - 6.9e-23 81.1 0.1 1.6e-22 79.9 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN94305.1 - 2.2e-07 30.5 0.0 2.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RLN94305.1 - 0.00066 19.3 0.0 0.0011 18.6 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SEFIR PF08357.11 RLN94305.1 - 0.0016 18.7 0.3 0.0029 17.9 0.3 1.4 1 0 0 1 1 1 1 SEFIR domain Gtr1_RagA PF04670.12 RLN94305.1 - 0.0091 15.4 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ANAPC4_WD40 PF12894.7 RLN94306.1 - 5.8e-09 36.1 0.1 0.00013 22.2 0.0 3.3 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Pex26 PF07163.12 RLN94306.1 - 0.029 13.7 0.1 0.057 12.7 0.1 1.4 1 0 0 1 1 1 0 Pex26 protein Frtz PF11768.8 RLN94306.1 - 0.045 12.1 0.0 0.063 11.6 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 RLN94306.1 - 0.097 13.6 0.5 21 6.2 0.0 3.6 3 1 0 3 3 3 0 WD domain, G-beta repeat Glyco_hydro_3 PF00933.21 RLN94307.1 - 2.6e-55 188.0 0.0 3.6e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN94307.1 - 2.7e-39 135.2 0.0 5e-39 134.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RLN94307.1 - 1.6e-14 53.8 0.1 4.2e-14 52.4 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 RLN94308.1 - 1.8e-55 188.5 0.0 2.2e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain MFS_1 PF07690.16 RLN94309.1 - 1.3e-19 70.4 32.9 8.9e-12 44.6 10.3 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 RLN94309.1 - 0.0039 15.6 8.5 0.0039 15.6 8.5 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector Glyco_hydro_3 PF00933.21 RLN94310.1 - 1.2e-53 182.6 0.0 1.7e-53 182.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN94310.1 - 1.5e-38 132.8 0.0 2.3e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RLN94310.1 - 2.6e-14 53.1 0.0 1e-13 51.2 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain LRR_adjacent PF08191.11 RLN94310.1 - 0.038 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 LRR adjacent Indigoidine_A PF04227.12 RLN94311.1 - 1.4e-72 244.6 2.3 1.3e-37 129.8 0.7 2.4 2 1 1 3 3 3 2 Indigoidine synthase A like protein PfkB PF00294.24 RLN94311.1 - 4.9e-14 52.3 0.4 1e-13 51.3 0.1 1.6 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Aha1_N PF09229.11 RLN94312.1 - 2e-15 57.2 0.0 3.8e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal zf-MYND PF01753.18 RLN94312.1 - 1.1e-09 38.2 14.3 1.8e-09 37.5 14.3 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 RLN94312.1 - 0.028 14.7 12.7 0.052 13.9 12.7 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PolC_DP2 PF03833.13 RLN94312.1 - 0.12 10.2 4.4 0.15 9.9 4.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 AAA PF00004.29 RLN94313.1 - 3.4e-36 124.6 0.0 1.5e-25 90.1 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN94313.1 - 2.1e-10 41.3 5.5 0.0022 18.4 0.1 4.8 3 2 2 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 RLN94313.1 - 1.2e-08 35.3 1.0 0.051 13.9 0.1 3.9 2 2 1 4 4 4 2 AAA domain AAA_33 PF13671.6 RLN94313.1 - 1e-07 32.2 0.0 0.0012 19.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 RLN94313.1 - 4.2e-06 26.5 1.6 0.36 10.4 0.1 3.5 2 1 1 3 3 3 2 AAA domain RuvB_N PF05496.12 RLN94313.1 - 4.6e-06 26.5 0.1 0.12 12.1 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 RLN94313.1 - 7.3e-06 25.4 0.1 0.0043 16.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 RLN94313.1 - 1.5e-05 25.0 0.3 0.0046 17.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 RLN94313.1 - 6.6e-05 22.9 0.0 0.011 15.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 RLN94313.1 - 6.9e-05 22.8 0.0 0.48 10.4 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 RLN94313.1 - 0.00012 21.9 0.0 0.55 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 RLN94313.1 - 0.00014 21.6 0.0 0.00033 20.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Mg_chelatase PF01078.21 RLN94313.1 - 0.00019 20.9 1.5 0.04 13.3 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 RLN94313.1 - 0.00021 21.1 0.3 0.081 12.6 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 RLN94313.1 - 0.0003 21.2 0.0 0.034 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 RLN94313.1 - 0.00033 20.6 0.1 0.29 11.1 0.0 3.3 3 0 0 3 3 3 1 NACHT domain Zeta_toxin PF06414.12 RLN94313.1 - 0.00042 19.7 0.1 0.19 11.0 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.22 RLN94313.1 - 0.0014 19.0 0.0 1.3 9.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 RLN94313.1 - 0.0016 18.4 0.0 0.27 11.1 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain NTPase_1 PF03266.15 RLN94313.1 - 0.0017 18.3 0.1 0.34 10.8 0.0 3.0 3 0 0 3 3 3 1 NTPase AAA_11 PF13086.6 RLN94313.1 - 0.0022 17.9 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 RLN94313.1 - 0.0025 18.3 0.0 0.56 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RLN94313.1 - 0.0032 17.2 0.1 0.065 13.0 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein TniB PF05621.11 RLN94313.1 - 0.0034 16.8 0.0 9.8 5.5 0.0 3.3 2 1 1 3 3 3 0 Bacterial TniB protein AAA_2 PF07724.14 RLN94313.1 - 0.0038 17.4 0.0 0.074 13.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Viral_helicase1 PF01443.18 RLN94313.1 - 0.0038 17.0 0.0 0.34 10.6 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 RLN94313.1 - 0.0055 16.6 0.2 0.13 12.1 0.0 2.7 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 RLN94313.1 - 0.0057 16.4 0.2 3 7.5 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase AAA_19 PF13245.6 RLN94313.1 - 0.0063 16.8 2.6 5.9 7.2 0.0 3.2 2 1 1 3 3 3 0 AAA domain AAA_28 PF13521.6 RLN94313.1 - 0.0075 16.5 0.1 0.19 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RLN94313.1 - 0.011 15.2 0.1 5.1 6.6 0.0 2.8 3 0 0 3 3 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 RLN94313.1 - 0.032 13.4 0.1 2.8 7.0 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.27 RLN94313.1 - 0.049 14.1 0.0 14 6.2 0.0 2.5 2 0 0 2 2 2 0 ABC transporter ResIII PF04851.15 RLN94313.1 - 0.054 13.5 0.0 3 7.8 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit cobW PF02492.19 RLN94313.1 - 0.063 12.9 0.6 13 5.4 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SKI PF01202.22 RLN94313.1 - 0.083 13.0 0.1 8.8 6.4 0.1 2.4 2 0 0 2 2 2 0 Shikimate kinase PhoH PF02562.16 RLN94313.1 - 0.15 11.5 1.9 2.1 7.8 0.3 2.7 3 0 0 3 3 3 0 PhoH-like protein Torsin PF06309.11 RLN94313.1 - 0.22 11.6 0.0 2.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Torsin Ndc1_Nup PF09531.10 RLN94314.1 - 0.0045 15.7 0.0 0.0045 15.7 0.0 3.0 3 1 1 4 4 4 1 Nucleoporin protein Ndc1-Nup DUF3817 PF12823.7 RLN94314.1 - 0.59 11.0 4.6 0.74 10.7 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3817) AzlD PF05437.12 RLN94314.1 - 7.6 6.8 14.2 0.095 12.9 4.5 2.8 3 1 0 3 3 3 0 Branched-chain amino acid transport protein (AzlD) AATase PF07247.12 RLN94315.1 - 2e-09 36.5 0.0 2.9e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase AATase PF07247.12 RLN94316.1 - 0.00076 18.1 0.0 0.0045 15.6 0.0 1.9 1 1 0 1 1 1 1 Alcohol acetyltransferase AAA_25 PF13481.6 RLN94318.1 - 1.4e-22 80.2 0.0 2.6e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Toprim_2 PF13155.6 RLN94318.1 - 2.7e-11 43.7 0.0 8e-11 42.2 0.0 1.9 2 0 0 2 2 1 1 Toprim-like AAA_22 PF13401.6 RLN94318.1 - 2.5e-08 34.3 0.0 7.2e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Toprim_3 PF13362.6 RLN94318.1 - 4.2e-07 30.2 0.0 2.7e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 Toprim domain AAA_16 PF13191.6 RLN94318.1 - 2.4e-06 28.0 0.0 5.1e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Toprim_4 PF13662.6 RLN94318.1 - 9e-06 26.1 0.0 6.7e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Toprim domain ATPase PF06745.13 RLN94318.1 - 2.7e-05 23.7 0.0 4.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.15 RLN94318.1 - 2.8e-05 23.6 0.0 4.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain ABC_tran PF00005.27 RLN94318.1 - 0.001 19.6 0.1 0.0019 18.7 0.1 1.5 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 RLN94318.1 - 0.0031 18.0 0.1 0.0066 17.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 RLN94318.1 - 0.0053 16.5 0.2 0.018 14.8 0.2 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 RLN94318.1 - 0.0057 16.4 0.0 0.0096 15.7 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein zf-CHC2 PF01807.20 RLN94318.1 - 0.0064 16.3 0.4 0.014 15.2 0.4 1.5 1 0 0 1 1 1 1 CHC2 zinc finger cobW PF02492.19 RLN94318.1 - 0.01 15.4 0.4 0.033 13.8 0.3 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 RLN94318.1 - 0.011 16.0 0.9 0.033 14.4 0.9 2.0 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RLN94318.1 - 0.012 15.5 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 RLN94318.1 - 0.013 15.5 0.0 0.032 14.2 0.0 1.7 2 0 0 2 2 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 RLN94318.1 - 0.018 15.0 0.0 0.067 13.1 0.0 1.9 3 0 0 3 3 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 RLN94318.1 - 0.02 15.0 0.1 0.05 13.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 RLN94318.1 - 0.021 14.8 0.2 0.041 13.8 0.2 1.5 1 0 0 1 1 1 0 NACHT domain PRK PF00485.18 RLN94318.1 - 0.021 14.5 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Toprim PF01751.22 RLN94318.1 - 0.027 14.7 0.0 0.18 12.1 0.0 2.2 1 1 0 1 1 1 0 Toprim domain AAA_5 PF07728.14 RLN94318.1 - 0.027 14.4 0.1 0.22 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 RLN94318.1 - 0.028 13.5 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 RLN94318.1 - 0.03 14.7 0.1 0.068 13.6 0.1 1.6 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 RLN94318.1 - 0.058 13.3 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 NTPase Lar_restr_allev PF14354.6 RLN94318.1 - 0.062 13.7 0.4 0.15 12.5 0.4 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar NB-ARC PF00931.22 RLN94318.1 - 0.069 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 RLN94318.1 - 0.095 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.9 RLN94318.1 - 0.11 11.7 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_21 PF13304.6 RLN94318.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 RLN94318.1 - 0.13 12.8 0.1 0.33 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 RLN94318.1 - 0.17 11.6 0.1 0.44 10.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain Zn_Tnp_IS1595 PF12760.7 RLN94318.1 - 0.24 11.4 1.7 0.75 9.8 1.7 1.9 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-CCHC_2 PF13696.6 RLN94318.1 - 0.7 9.8 4.7 0.73 9.7 1.6 2.3 2 0 0 2 2 2 0 Zinc knuckle CCDC71L PF15374.6 RLN94319.1 - 0.16 11.2 14.1 0.19 11.0 14.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L SASP_gamma PF04259.14 RLN94319.1 - 1.8 9.1 12.9 0.23 12.0 7.6 2.0 2 0 0 2 2 2 0 Small, acid-soluble spore protein, gamma-type DUF3381 PF11861.8 RLN94319.1 - 2.5 7.9 16.6 4.5 7.0 13.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Zip PF02535.22 RLN94319.1 - 5 6.3 4.3 7.4 5.7 4.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 RLN94319.1 - 9.4 4.4 10.8 12 4.0 10.8 1.3 1 0 0 1 1 1 0 CDC45-like protein HhH-GPD PF00730.25 RLN94320.1 - 2.9e-22 79.1 0.0 5.7e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 RLN94320.1 - 4.3e-06 26.3 0.0 8.8e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif Phage_integrase PF00589.22 RLN94321.1 - 0.002 17.9 0.0 0.0037 17.1 0.0 1.5 1 1 0 1 1 1 1 Phage integrase family DUF4833 PF16117.5 RLN94322.1 - 3.4e-40 137.2 0.0 4.2e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4833) MFS_MOT1 PF16983.5 RLN94323.1 - 1.3e-51 173.7 29.3 5.6e-28 97.6 8.0 2.7 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily CHD5 PF04420.14 RLN94323.1 - 0.04 13.8 0.3 0.14 12.0 0.3 1.9 1 0 0 1 1 1 0 CHD5-like protein RPN2_C PF18004.1 RLN94324.1 - 1.3e-37 129.2 6.8 1.9e-37 128.6 6.8 1.2 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 RLN94324.1 - 2.4e-20 71.9 15.1 3.1e-08 33.7 0.1 6.2 6 0 0 6 6 6 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 RLN94324.1 - 2.4e-18 66.3 1.5 5.5e-14 52.3 0.2 3.8 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.22 RLN94324.1 - 4.1e-06 26.6 1.8 0.28 11.6 0.1 4.7 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 RLN94324.1 - 5.8e-05 23.5 2.4 0.11 13.0 0.0 4.3 4 1 1 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 RLN94324.1 - 0.00054 20.0 1.2 0.51 10.4 0.0 2.9 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 AveC_like PF17198.4 RLN94324.1 - 0.15 11.5 0.7 1.3 8.4 0.1 2.1 2 0 0 2 2 2 0 Spirocyclase AveC-like Arm PF00514.23 RLN94324.1 - 0.43 10.7 1.7 88 3.4 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Vfa1 PF08432.10 RLN94324.1 - 5 7.4 9.4 7.7 6.8 9.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sec1 PF00995.23 RLN94325.1 - 1.8e-123 413.8 0.0 2.1e-123 413.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family KH_8 PF17903.1 RLN94325.1 - 0.16 12.1 0.1 2.2 8.4 0.0 2.7 3 0 0 3 3 3 0 Krr1 KH1 domain Aa_trans PF01490.18 RLN94326.1 - 9.3e-37 126.7 17.2 1.2e-36 126.4 17.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Bromodomain PF00439.25 RLN94327.1 - 1.2e-21 76.6 0.1 2.2e-21 75.7 0.1 1.5 1 0 0 1 1 1 1 Bromodomain COBRA1 PF06209.13 RLN94327.1 - 8e-12 44.8 3.6 0.00049 19.1 2.1 3.6 3 1 0 3 3 3 3 Cofactor of BRCA1 (COBRA1) Myb_DNA-bind_4 PF13837.6 RLN94328.1 - 3.3e-06 27.4 0.2 0.0065 16.8 0.0 3.2 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 RLN94328.1 - 0.00018 22.4 1.0 0.17 12.9 0.0 2.9 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain DUF573 PF04504.14 RLN94328.1 - 0.0055 17.3 0.2 1.1 10.0 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function, DUF573 GLTP PF08718.11 RLN94328.1 - 0.15 12.3 2.1 0.14 12.5 0.4 1.7 2 0 0 2 2 2 0 Glycolipid transfer protein (GLTP) PAP1 PF08601.10 RLN94328.1 - 1.5 8.5 7.7 2.5 7.7 7.7 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Phage_holin_7_1 PF16081.5 RLN94328.1 - 4.4 7.5 7.3 9.1 6.5 7.3 1.5 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Sugar_tr PF00083.24 RLN94329.1 - 2.3e-32 112.4 8.1 2.6e-32 112.3 8.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2583 PF10762.9 RLN94329.1 - 5.7 7.4 9.5 0.97 9.9 5.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) Retrotrans_gag PF03732.17 RLN94331.1 - 6.8e-06 26.3 0.1 8.4e-05 22.8 0.0 2.3 2 1 0 2 2 2 1 Retrotransposon gag protein Baculo_PEP_C PF04513.12 RLN94331.1 - 0.00054 20.0 3.0 0.00054 20.0 3.0 1.5 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Dynamitin PF04912.14 RLN94331.1 - 0.008 15.6 1.2 0.0099 15.2 1.2 1.1 1 0 0 1 1 1 1 Dynamitin Fmp27_WPPW PF10359.9 RLN94331.1 - 0.012 14.5 0.5 0.015 14.2 0.5 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF948 PF06103.11 RLN94331.1 - 0.017 15.4 1.4 0.051 13.8 1.0 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) LPP PF04728.13 RLN94331.1 - 0.045 14.2 2.8 0.2 12.1 1.0 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper SlyX PF04102.12 RLN94331.1 - 0.054 14.1 2.7 17 6.1 0.1 3.3 1 1 1 3 3 3 0 SlyX DUF4665 PF15679.5 RLN94331.1 - 0.074 13.7 0.2 1.4 9.6 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) Fibritin_C PF07921.12 RLN94331.1 - 0.089 12.9 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Fibritin C-terminal region COG2 PF06148.11 RLN94331.1 - 0.17 12.0 1.3 0.49 10.5 1.3 1.8 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Chromo PF00385.24 RLN94332.1 - 1.2e-06 28.4 0.2 2.1e-06 27.5 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ank_5 PF13857.6 RLN94333.1 - 1.6e-15 56.9 2.3 0.011 16.1 0.0 6.8 1 1 6 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN94333.1 - 2.9e-15 56.4 0.4 0.00058 20.4 0.1 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN94333.1 - 2.1e-13 50.7 0.3 1.3e-05 25.6 0.1 3.3 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN94333.1 - 1.7e-06 27.9 0.0 53 4.9 0.0 6.2 6 1 0 6 6 6 0 Ankyrin repeat SAM_1 PF00536.30 RLN94333.1 - 0.066 13.7 0.8 15 6.1 0.0 4.1 4 1 1 5 5 5 0 SAM domain (Sterile alpha motif) Ank PF00023.30 RLN94333.1 - 0.081 13.4 0.0 20 5.9 0.0 3.8 3 1 0 3 3 3 0 Ankyrin repeat Chorion_S16 PF05836.12 RLN94333.1 - 0.089 13.0 0.4 4.6 7.5 0.0 2.6 1 1 1 2 2 2 0 Chorion protein S16 SAM_3 PF18016.1 RLN94333.1 - 6.3 6.7 6.7 16 5.4 0.0 3.9 4 1 1 5 5 5 0 SAM domain (Sterile alpha motif) PH PF00169.29 RLN94335.1 - 1.6e-07 31.8 0.3 1.1e-06 29.1 0.0 2.4 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 RLN94335.1 - 0.21 12.0 2.5 2 8.9 0.9 2.6 1 1 1 2 2 2 0 Pleckstrin homology domain Vpu PF00558.19 RLN94336.1 - 0.086 12.6 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 Vpu protein Sulfatase PF00884.23 RLN94337.1 - 1.5e-29 103.4 0.5 1e-28 100.7 0.5 2.2 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 RLN94337.1 - 0.0001 22.1 0.1 0.0013 18.4 0.0 2.2 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 RLN94337.1 - 0.0019 16.9 0.2 0.0037 15.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Peptidase_C78 PF07910.13 RLN94338.1 - 2.5e-41 141.5 0.2 3.8e-41 140.9 0.2 1.3 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 RLN94338.1 - 0.00077 19.0 0.2 0.0017 17.9 0.1 1.6 2 0 0 2 2 2 1 Peptidase family C54 mRNA_decap_C PF16741.5 RLN94338.1 - 0.24 10.7 1.8 1.8 7.9 1.5 2.3 2 0 0 2 2 2 0 mRNA-decapping enzyme C-terminus DUF883 PF05957.13 RLN94338.1 - 7.9 7.2 6.6 1 10.0 0.6 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Glycos_transf_1 PF00534.20 RLN94339.1 - 0.0022 17.6 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RLN94339.1 - 0.0024 18.3 0.0 0.0047 17.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Ribosomal_L35p PF01632.19 RLN94341.1 - 8e-19 67.9 10.2 8.8e-19 67.8 10.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 PCP_red PF08369.10 RLN94341.1 - 0.03 14.5 0.3 0.057 13.6 0.3 1.5 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit Hydrolase_4 PF12146.8 RLN94342.1 - 1.1e-13 51.1 0.3 1.7e-10 40.6 0.2 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN94342.1 - 5e-09 36.2 0.2 1.7e-07 31.2 0.2 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 RLN94342.1 - 1.2e-05 25.0 0.0 3.5e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Elicitin PF00964.17 RLN94342.1 - 0.00099 19.2 0.5 0.0019 18.3 0.5 1.5 1 0 0 1 1 1 1 Elicitin zf-RanBP PF00641.18 RLN94342.1 - 0.049 13.0 0.2 0.1 11.9 0.2 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others PhoPQ_related PF10142.9 RLN94342.1 - 0.072 11.7 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein zf-AN1 PF01428.16 RLN94344.1 - 5.2e-20 71.3 39.4 1e-12 48.0 9.7 4.8 4 1 1 5 5 5 2 AN1-like Zinc finger zf-C2H2_4 PF13894.6 RLN94344.1 - 6.2e-05 23.5 0.4 0.018 15.8 0.1 5.5 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.26 RLN94344.1 - 0.00019 21.7 0.1 0.02 15.3 0.0 4.8 6 0 0 6 6 4 2 Zinc finger, C2H2 type PRR18 PF15671.5 RLN94344.1 - 0.011 15.6 10.4 0.017 15.0 10.4 1.2 1 0 0 1 1 1 0 Proline-rich protein family 18 zf-C2H2_9 PF16293.5 RLN94344.1 - 0.016 15.1 3.6 1.2 9.1 0.1 3.4 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) Rad50_zn_hook PF04423.14 RLN94344.1 - 0.057 13.3 3.6 2.3 8.1 0.0 3.5 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C2H2_6 PF13912.6 RLN94344.1 - 0.08 13.0 10.3 0.33 11.0 0.0 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 RLN94344.1 - 0.51 11.0 12.0 1.6 9.4 0.0 4.1 4 1 0 4 4 4 0 FOXP coiled-coil domain zf-met PF12874.7 RLN94344.1 - 0.55 10.7 0.2 0.55 10.7 0.2 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type GAGA PF09237.11 RLN94344.1 - 3.9 7.4 12.9 4.9 7.0 0.1 4.2 3 1 1 4 4 4 0 GAGA factor Inhibitor_I36 PF03995.13 RLN94344.1 - 6.7 6.7 10.3 0.16 11.9 1.5 2.5 2 1 0 2 2 2 0 Peptidase inhibitor family I36 Hist_deacetyl PF00850.19 RLN94345.1 - 3.6e-57 194.2 0.0 8.1e-57 193.0 0.0 1.5 1 1 0 1 1 1 1 Histone deacetylase domain Dynein_light PF01221.18 RLN94345.1 - 3.2e-41 139.5 1.8 3.2e-41 139.5 1.8 1.8 2 0 0 2 2 2 1 Dynein light chain type 1 HALZ PF02183.18 RLN94346.1 - 0.25 11.6 3.3 3 8.1 0.2 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Lzipper-MIP1 PF14389.6 RLN94347.1 - 0.15 12.4 0.3 0.42 11.0 0.3 1.8 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Glyco_hydro_3 PF00933.21 RLN94348.1 - 7.1e-51 173.5 0.0 2.1e-50 171.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN94348.1 - 8.1e-40 137.0 0.4 2.1e-39 135.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RLN94348.1 - 4.1e-12 46.0 0.1 8.8e-12 45.0 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.11 RLN94348.1 - 0.1 12.9 1.0 0.22 11.8 0.2 1.9 2 0 0 2 2 2 0 CARDB Rad51 PF08423.11 RLN94349.1 - 3.7e-81 272.1 0.3 7.8e-81 271.1 0.3 1.5 1 0 0 1 1 1 1 Rad51 ABC_membrane PF00664.23 RLN94349.1 - 4.6e-49 167.5 19.7 6.4e-49 167.0 19.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN94349.1 - 4.6e-35 121.1 0.0 4.7e-34 117.9 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_25 PF13481.6 RLN94349.1 - 7.5e-11 42.0 0.9 4.6e-07 29.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain HHH_5 PF14520.6 RLN94349.1 - 6.9e-08 33.0 2.5 3.4e-07 30.8 0.6 3.1 2 1 1 3 3 3 1 Helix-hairpin-helix domain RecA PF00154.21 RLN94349.1 - 2.4e-07 30.5 0.0 4.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_24 PF13479.6 RLN94349.1 - 6.2e-06 26.1 0.0 0.036 13.8 0.0 2.6 2 1 0 2 2 2 2 AAA domain ATPase PF06745.13 RLN94349.1 - 7.9e-06 25.4 2.5 0.00012 21.6 0.0 3.1 3 0 0 3 3 3 1 KaiC AAA_22 PF13401.6 RLN94349.1 - 2.2e-05 24.7 0.6 0.04 14.2 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 RLN94349.1 - 0.00092 19.5 0.1 0.93 9.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RLN94349.1 - 0.0031 16.8 0.0 0.0086 15.4 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 RLN94349.1 - 0.0042 16.8 0.5 0.02 14.7 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 RLN94349.1 - 0.0055 16.2 4.2 0.066 12.6 0.0 2.9 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RLN94349.1 - 0.008 16.6 2.3 0.025 14.9 1.1 2.5 2 1 1 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 RLN94349.1 - 0.014 15.3 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase RNA_pol_A_CTD PF03118.15 RLN94349.1 - 0.018 14.8 0.1 0.83 9.5 0.0 2.7 1 1 1 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain ABC_ATPase PF09818.9 RLN94349.1 - 0.019 13.8 0.0 0.038 12.8 0.0 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class APS_kinase PF01583.20 RLN94349.1 - 0.023 14.6 0.2 0.063 13.2 0.1 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_21 PF13304.6 RLN94349.1 - 0.033 14.0 0.5 0.99 9.1 0.1 2.2 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 RLN94349.1 - 0.036 14.6 0.0 1.5 9.4 0.0 2.9 2 1 1 3 3 3 0 AAA domain DUF87 PF01935.17 RLN94349.1 - 0.052 13.6 0.1 0.16 12.0 0.1 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain HHH PF00633.23 RLN94349.1 - 0.079 12.9 0.2 0.95 9.5 0.0 2.9 3 0 0 3 3 3 0 Helix-hairpin-helix motif AAA_15 PF13175.6 RLN94349.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 RLN94349.1 - 0.17 11.0 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Rad51 PF08423.11 RLN94350.1 - 2.9e-15 56.2 0.8 4.7e-12 45.7 0.0 2.0 1 1 1 2 2 2 2 Rad51 DUF4407 PF14362.6 RLN94352.1 - 0.13 11.6 8.6 0.2 11.0 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 RLN94352.1 - 0.68 10.6 3.0 3.3 8.4 0.1 2.4 2 0 0 2 2 2 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 RLN94352.1 - 1.4 8.9 11.9 33 4.5 11.9 2.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Com_YlbF PF06133.11 RLN94352.1 - 1.8 9.2 8.0 8 7.1 0.6 2.5 3 0 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA THOC7 PF05615.13 RLN94352.1 - 2.3 8.5 13.6 7.1 6.9 0.5 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 AAA_13 PF13166.6 RLN94352.1 - 3.8 6.0 6.6 7.1 5.1 6.6 1.3 1 1 0 1 1 1 0 AAA domain DUF3450 PF11932.8 RLN94352.1 - 4.1 6.6 15.5 0.16 11.3 6.9 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) GAS PF13851.6 RLN94352.1 - 6.1 6.1 12.1 2.3 7.5 4.3 2.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding TauD PF02668.16 RLN94353.1 - 1.6e-21 77.3 0.1 2.5e-21 76.7 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 RLN94353.1 - 1.2e-11 45.1 0.5 1.5e-10 41.6 0.3 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF971) IL17 PF06083.11 RLN94353.1 - 0.042 14.3 0.0 0.083 13.4 0.0 1.4 1 0 0 1 1 1 0 Interleukin-17 HapK PF11639.8 RLN94353.1 - 0.11 13.0 0.1 0.31 11.5 0.1 1.8 1 0 0 1 1 1 0 REDY-like protein HapK Ank_2 PF12796.7 RLN94354.1 - 5.9e-13 49.2 0.1 4.6e-06 27.1 0.0 3.2 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN94354.1 - 2.3e-11 44.0 0.2 0.0094 16.5 0.1 4.8 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN94354.1 - 2.2e-08 34.2 5.5 5e-05 23.5 0.2 3.7 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN94354.1 - 4.2e-07 30.1 0.1 4.4 7.9 0.0 4.7 2 2 2 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 RLN94354.1 - 2.6e-06 27.3 2.5 3.7 8.4 0.0 5.4 5 1 0 5 5 5 2 Ankyrin repeat Pkinase_Tyr PF07714.17 RLN94355.1 - 1.3e-49 168.8 0.0 1.5e-49 168.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN94355.1 - 3.6e-47 161.0 0.0 4.9e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 RLN94355.1 - 0.14 12.1 0.0 1 9.3 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family FYVE PF01363.21 RLN94356.1 - 4e-14 52.5 14.4 8e-14 51.5 14.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 RLN94356.1 - 7.4e-07 29.9 0.1 1.9e-06 28.5 0.1 1.7 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 RLN94356.1 - 2.3e-06 28.0 0.0 4.6e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 GAF domain SpoVT_C PF15714.5 RLN94356.1 - 0.0079 16.3 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 Stage V sporulation protein T C-terminal, transcription factor MlaD PF02470.20 RLN94356.1 - 0.023 15.0 0.0 0.054 13.8 0.0 1.6 1 0 0 1 1 1 0 MlaD protein FYVE_2 PF02318.16 RLN94356.1 - 0.95 9.7 8.3 2.8 8.2 8.3 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger Uso1_p115_C PF04871.13 RLN94359.1 - 0.036 14.4 5.0 0.088 13.2 5.0 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region UPF0193 PF05250.11 RLN94360.1 - 2.6e-07 30.7 2.6 3.2e-06 27.1 0.9 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0193) DUF1640 PF07798.11 RLN94360.1 - 0.056 13.5 1.6 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) TB2_DP1_HVA22 PF03134.19 RLN94361.1 - 3e-14 52.7 19.7 2.9e-12 46.3 2.6 3.4 3 0 0 3 3 3 2 TB2/DP1, HVA22 family Paz_1 PF18349.1 RLN94361.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 PAZ domain FancD2 PF14631.6 RLN94362.1 - 2.2e-38 131.5 8.9 1.8e-37 128.4 8.9 1.9 1 1 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease FancD2 PF14631.6 RLN94363.1 - 2.3e-51 174.5 5.1 2.7e-35 121.3 2.6 3.1 2 1 1 3 3 3 3 Fanconi anaemia protein FancD2 nuclease PH PF00169.29 RLN94364.1 - 0.00064 20.2 0.0 0.0017 18.9 0.0 1.8 1 0 0 1 1 1 1 PH domain Peptidase_M4_C PF02868.15 RLN94364.1 - 0.092 12.6 0.7 4.9 7.0 0.3 2.3 1 1 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain IQ PF00612.27 RLN94365.1 - 9.6e-11 40.5 14.5 0.013 15.2 0.5 5.2 4 0 0 4 4 4 4 IQ calmodulin-binding motif V_ATPase_I PF01496.19 RLN94365.1 - 1.8 6.4 5.9 2.8 5.7 5.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PIP5K PF01504.18 RLN94366.1 - 3.7e-61 206.8 0.0 2e-59 201.1 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase NMN_transporter PF04973.12 RLN94366.1 - 0.00044 20.3 0.9 0.00044 20.3 0.9 1.8 2 0 0 2 2 2 1 Nicotinamide mononucleotide transporter DUF4010 PF13194.6 RLN94366.1 - 0.5 10.0 2.9 2.2 7.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) Frizzled PF01534.17 RLN94366.1 - 0.71 8.9 9.8 6.8 5.6 9.8 2.0 1 1 0 1 1 1 0 Frizzled/Smoothened family membrane region WD40 PF00400.32 RLN94367.1 - 1.3e-32 111.3 42.3 0.0019 19.0 0.0 20.6 21 0 0 21 21 21 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN94367.1 - 2.4e-22 79.0 0.1 0.00096 19.4 0.0 9.7 7 2 4 11 11 11 4 Anaphase-promoting complex subunit 4 WD40 domain HELP PF03451.14 RLN94367.1 - 9.3e-19 67.1 0.0 7.5e-08 32.1 0.0 3.5 3 0 0 3 3 3 3 HELP motif Ge1_WD40 PF16529.5 RLN94367.1 - 6.1e-05 22.1 0.1 1.6 7.6 0.0 5.9 5 2 1 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 RLN94367.1 - 2.2 8.9 17.0 30 5.3 0.1 8.7 9 0 0 9 9 9 0 PQQ-like domain bZIP_2 PF07716.15 RLN94369.1 - 6.7e-09 35.7 7.3 2.1e-08 34.1 7.3 1.8 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 RLN94369.1 - 1.8e-06 27.9 7.3 5.4e-06 26.4 7.3 1.8 1 0 0 1 1 1 1 bZIP transcription factor MARVEL PF01284.23 RLN94370.1 - 4.3e-05 23.6 4.3 7.1e-05 22.9 4.3 1.4 1 0 0 1 1 1 1 Membrane-associating domain GvpH PF05455.11 RLN94370.1 - 0.035 14.2 0.2 0.36 10.9 0.1 2.3 2 0 0 2 2 2 0 GvpH TetR_C_36 PF18598.1 RLN94370.1 - 0.052 13.5 0.8 1.6 8.7 0.6 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Stc1 PF12898.7 RLN94370.1 - 0.098 13.2 6.5 0.33 11.5 6.5 2.0 1 1 0 1 1 1 0 Stc1 domain DUF3460 PF11943.8 RLN94370.1 - 0.26 11.6 1.3 6.6 7.1 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3460) ADIP PF11559.8 RLN94370.1 - 1.9 8.6 9.5 0.057 13.5 2.2 2.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Ost5 PF05251.12 RLN94370.1 - 6.8 7.0 7.4 5.1 7.4 3.8 2.3 1 1 1 2 2 2 0 Oligosaccharyltransferase subunit 5 Tim44 PF04280.15 RLN94371.1 - 0.021 14.9 0.7 0.065 13.3 0.1 2.0 3 0 0 3 3 3 0 Tim44-like domain DUF547 PF04784.14 RLN94372.1 - 1.5e-07 31.5 0.5 5.4e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF547 Tim44 PF04280.15 RLN94374.1 - 0.012 15.8 1.7 0.066 13.3 0.1 2.3 2 0 0 2 2 2 0 Tim44-like domain VASt PF16016.5 RLN94375.1 - 5.3e-23 82.1 0.0 1.2e-22 80.9 0.0 1.7 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain FYVE PF01363.21 RLN94375.1 - 1.2e-11 44.6 7.4 2.8e-11 43.4 7.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger GRAM PF02893.20 RLN94375.1 - 1.1e-07 31.8 0.4 3.8e-07 30.0 0.1 2.1 2 0 0 2 2 2 1 GRAM domain IBR PF01485.21 RLN94375.1 - 0.21 11.8 3.4 0.67 10.2 3.4 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 RLN94375.1 - 2.1 8.6 7.3 5.4 7.3 7.3 1.7 1 0 0 1 1 1 0 AN1-like Zinc finger Choline_transpo PF04515.12 RLN94376.1 - 6.3e-44 150.5 12.4 6.3e-44 150.5 12.4 2.9 2 1 1 3 3 3 2 Plasma-membrane choline transporter NUDE_C PF04880.13 RLN94376.1 - 0.54 10.7 2.6 3.3 8.1 0.3 2.2 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region GRP PF07172.11 RLN94379.1 - 6.8 7.5 9.8 2.3 9.0 4.9 2.5 2 0 0 2 2 2 0 Glycine rich protein family Sensor PF13796.6 RLN94380.1 - 1.7e-08 34.7 40.9 3.9e-05 23.7 17.4 2.8 2 1 0 2 2 2 2 Putative sensor CAP PF00188.26 RLN94382.1 - 3.8e-19 69.7 2.8 7.8e-19 68.8 2.8 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PAN_4 PF14295.6 RLN94382.1 - 4.1e-08 33.0 7.3 1e-07 31.7 7.3 1.7 1 0 0 1 1 1 1 PAN domain DUF5308 PF17233.2 RLN94382.1 - 0.53 10.5 6.4 12 6.1 0.0 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5308) CAP PF00188.26 RLN94383.1 - 1.5e-18 67.9 2.3 2.6e-18 67.1 2.3 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PAN_4 PF14295.6 RLN94383.1 - 1.1e-05 25.3 6.1 1.1e-05 25.3 6.1 2.3 2 0 0 2 2 2 1 PAN domain NYD-SP28 PF14772.6 RLN94384.1 - 0.083 13.0 6.9 0.36 10.9 0.0 2.3 2 0 0 2 2 2 0 Sperm tail FAM104 PF15434.6 RLN94384.1 - 4.1 8.0 6.5 7.7 7.1 6.5 1.7 1 1 0 1 1 1 0 Family 104 NYD-SP28 PF14772.6 RLN94385.1 - 0.17 12.0 6.6 0.36 10.9 0.0 2.3 2 0 0 2 2 2 0 Sperm tail DUF16 PF01519.16 RLN94386.1 - 0.058 13.9 27.7 0.16 12.5 3.4 5.9 4 1 0 4 4 4 0 Protein of unknown function DUF16 Cullin_Nedd8 PF10557.9 RLN94386.1 - 0.069 13.2 2.4 0.14 12.2 0.5 2.7 2 0 0 2 2 2 0 Cullin protein neddylation domain DUF3244 PF11589.8 RLN94386.1 - 1 9.5 2.9 2.1 8.5 0.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3244) Pkinase PF00069.25 RLN94387.1 - 2.2e-63 214.1 1.7 2.2e-62 210.8 0.0 3.0 3 1 0 3 3 3 1 Protein kinase domain DUF4457 PF14652.6 RLN94387.1 - 6.8e-63 212.9 0.0 1e-62 212.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4457) Pkinase_Tyr PF07714.17 RLN94387.1 - 1.8e-41 142.1 0.1 5.1e-41 140.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN94387.1 - 0.00054 18.8 0.0 0.0019 17.1 0.0 1.8 1 1 0 1 1 1 1 Fungal protein kinase Arm PF00514.23 RLN94387.1 - 0.00068 19.6 5.7 1.7 8.8 0.0 5.2 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Kinase-like PF14531.6 RLN94387.1 - 0.0019 17.6 0.0 0.0085 15.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 RLN94387.1 - 0.015 14.7 0.0 0.04 13.3 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Npa1 PF11707.8 RLN94387.1 - 0.056 12.8 0.3 0.16 11.3 0.3 1.7 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal Seadorna_VP7 PF07387.11 RLN94387.1 - 0.73 8.8 3.0 0.47 9.5 0.0 2.2 3 0 0 3 3 3 0 Seadornavirus VP7 Mtc PF03820.17 RLN94388.1 - 3e-133 443.7 2.5 3.4e-133 443.5 2.5 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier LRR_9 PF14580.6 RLN94389.1 - 2.4e-15 56.5 2.9 4e-15 55.8 2.9 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 RLN94389.1 - 8.5e-07 29.2 10.5 0.0042 17.5 2.0 3.8 1 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN94389.1 - 3.3e-05 23.6 3.4 3.3e-05 23.6 3.4 3.0 4 0 0 4 4 4 1 Leucine rich repeat DUF359 PF04019.12 RLN94389.1 - 0.029 14.0 0.2 0.029 14.0 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF359) Ufm1 PF03671.14 RLN94390.1 - 2e-18 66.2 0.1 3.6e-10 39.8 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin fold modifier 1 protein AA_permease_2 PF13520.6 RLN94391.1 - 2.4e-46 158.5 46.8 3.2e-46 158.0 46.8 1.2 1 0 0 1 1 1 1 Amino acid permease Cyclin_N PF00134.23 RLN94392.1 - 8.4e-11 41.7 0.1 1.7e-10 40.7 0.1 1.5 1 1 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 RLN94392.1 - 0.072 13.1 0.3 0.072 13.1 0.3 2.3 2 0 0 2 2 2 0 Transcription factor TFIIB repeat TFIIB_C_1 PF18542.1 RLN94392.1 - 0.14 12.2 1.8 0.27 11.3 0.5 2.2 1 1 1 2 2 2 0 Transcription factor IIB C-terminal module 1 SK_channel PF03530.14 RLN94393.1 - 5e-05 23.3 0.1 0.00015 21.7 0.1 1.8 1 0 0 1 1 1 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 RLN94393.1 - 0.004 17.1 4.6 0.0097 15.8 4.6 1.6 1 0 0 1 1 1 1 Ion channel MFS_1 PF07690.16 RLN94394.1 - 3.4e-08 32.8 21.6 7.4e-08 31.7 21.6 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 RLN94394.1 - 2.4e-07 30.6 8.4 5.6e-07 29.4 8.4 1.5 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Exo_endo_phos PF03372.23 RLN94394.1 - 2.9e-07 30.3 0.1 8e-07 28.8 0.1 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_1 PF00515.28 RLN94394.1 - 0.0076 16.0 5.3 0.23 11.3 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 RLN94394.1 - 0.021 14.9 4.5 0.56 10.5 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat FYVE PF01363.21 RLN94395.1 - 0.0018 18.3 3.3 0.0034 17.5 3.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger GAF_3 PF13492.6 RLN94395.1 - 0.0056 17.0 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 RLN94395.1 - 0.014 15.7 0.0 0.024 14.9 0.0 1.5 1 1 0 1 1 1 0 GAF domain Fer2_3 PF13085.6 RLN94395.1 - 0.12 12.4 0.4 0.4 10.7 0.4 1.9 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain PI3_PI4_kinase PF00454.27 RLN94396.1 - 5.3e-51 173.8 0.0 4.9e-36 124.8 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 RLN94396.1 - 6.2e-48 162.7 0.1 1.1e-47 161.9 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 RLN94396.1 - 2.6e-26 92.2 0.0 4.8e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 RLN94396.1 - 0.028 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Med12-LCEWAV PF12145.8 RLN94397.1 - 1.2e-05 24.4 0.0 4.4e-05 22.5 0.0 1.8 1 1 1 2 2 2 1 Eukaryotic Mediator 12 subunit domain Ion_trans PF00520.31 RLN94398.1 - 1.2e-15 57.4 10.8 2.4e-14 53.2 10.8 2.0 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RLN94398.1 - 5.7e-10 39.0 10.1 5.7e-10 39.0 10.1 2.6 2 1 0 2 2 2 2 Ion channel ABC_membrane PF00664.23 RLN94401.1 - 7.2e-49 166.9 1.1 9.4e-49 166.5 1.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN94401.1 - 6.9e-16 59.0 0.0 1.2e-15 58.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 RLN94401.1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN94401.1 - 0.017 14.8 0.3 0.037 13.8 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.20 RLN94401.1 - 0.062 13.2 0.1 1.1 9.1 0.0 2.6 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA_16 PF13191.6 RLN94401.1 - 0.081 13.3 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 RLN94401.1 - 0.083 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RLN94401.1 - 0.15 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin SPRY PF00622.28 RLN94402.1 - 1.3e-26 93.1 0.0 2.7e-14 53.3 0.0 2.5 2 0 0 2 2 2 2 SPRY domain Vps62 PF06101.11 RLN94402.1 - 1.4e-07 30.2 0.0 2.9e-07 29.2 0.0 1.4 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 UBA PF00627.31 RLN94402.1 - 1.3e-06 28.2 0.1 0.0023 17.8 0.0 2.8 2 0 0 2 2 2 2 UBA/TS-N domain MscL PF01741.18 RLN94403.1 - 0.055 13.8 0.0 0.073 13.4 0.0 1.2 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL Amnionless PF14828.6 RLN94404.1 - 0.011 14.5 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Amnionless NUP214 PF16755.5 RLN94404.1 - 0.046 12.9 0.0 0.058 12.6 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 FHIPEP PF00771.20 RLN94405.1 - 0.034 12.6 0.1 0.041 12.4 0.1 1.1 1 0 0 1 1 1 0 FHIPEP family CcmD PF04995.14 RLN94405.1 - 0.3 11.2 1.5 0.5 10.5 1.5 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DDE_1 PF03184.19 RLN94407.1 - 2.6e-38 131.4 1.6 4.4e-38 130.7 1.6 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN94407.1 - 1.8e-13 50.3 0.1 5.6e-13 48.7 0.1 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 RLN94407.1 - 1.5e-05 24.6 0.1 4.8e-05 23.0 0.1 1.9 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain VRR_NUC PF08774.11 RLN94408.1 - 2.8e-07 30.6 0.1 0.0025 17.9 0.0 3.5 3 1 1 4 4 4 2 VRR-NUC domain UPF0176_N PF17773.1 RLN94409.1 - 3.2e-23 81.9 0.0 5.7e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 RLN94409.1 - 2.3e-13 50.3 6.7 4.2e-13 49.4 6.7 1.4 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 RLN94409.1 - 3.3e-10 40.4 0.0 6.3e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Acylphosphatase PF00708.18 RLN94409.1 - 0.078 13.4 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Acylphosphatase Plasmid_RAQPRD PF09686.10 RLN94409.1 - 0.43 10.8 3.2 4.1 7.7 0.0 3.1 3 1 0 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Paired_CXXCH_1 PF09699.10 RLN94409.1 - 6.8 6.5 8.0 3.7 7.4 5.6 1.8 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) WW PF00397.26 RLN94410.1 - 1.1e-06 28.6 3.6 7.9e-05 22.7 1.2 2.5 2 0 0 2 2 2 2 WW domain Trypsin_2 PF13365.6 RLN94410.1 - 6.5e-06 27.1 0.0 1.3e-05 26.1 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain PUL PF08324.11 RLN94410.1 - 0.085 12.1 1.4 0.099 11.9 0.1 1.7 2 0 0 2 2 2 0 PUL domain RPA_interact_C PF14768.6 RLN94410.1 - 0.21 12.2 1.5 4.5 7.9 0.6 2.8 2 0 0 2 2 2 0 Replication protein A interacting C-terminal BK_channel_a PF03493.18 RLN94411.1 - 3.1e-27 94.6 0.1 8.6e-27 93.2 0.1 1.8 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 RLN94411.1 - 2.6e-11 43.3 9.9 4.5e-11 42.6 8.2 2.4 2 1 0 2 2 2 1 Ion channel Ion_trans PF00520.31 RLN94411.1 - 0.0001 21.6 11.0 0.00019 20.7 11.0 1.4 1 0 0 1 1 1 1 Ion transport protein Lig_chan PF00060.26 RLN94411.1 - 0.0006 19.7 0.3 0.0014 18.4 0.3 1.6 1 0 0 1 1 1 1 Ligand-gated ion channel TrkA_N PF02254.18 RLN94411.1 - 0.0054 17.0 0.7 0.69 10.2 0.2 2.5 2 0 0 2 2 2 1 TrkA-N domain DUF4501 PF14946.6 RLN94411.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) Capsule_synth PF05159.14 RLN94411.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Capsule polysaccharide biosynthesis protein DUF2431 PF10354.9 RLN94412.1 - 3.3e-38 131.6 0.0 4.9e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) CH_2 PF06294.11 RLN94412.1 - 1.5e-21 76.3 0.2 2.8e-21 75.4 0.2 1.4 1 0 0 1 1 1 1 CH-like domain in sperm protein CH PF00307.31 RLN94412.1 - 0.0062 16.7 0.1 0.011 15.9 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain ADK PF00406.22 RLN94413.1 - 5.1e-09 36.4 0.1 1.9e-07 31.3 0.0 3.5 4 1 0 4 4 4 1 Adenylate kinase AAA_33 PF13671.6 RLN94413.1 - 0.0027 17.9 2.6 0.61 10.2 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.6 RLN94413.1 - 0.0069 16.8 4.2 0.055 13.9 0.0 4.2 6 0 0 6 6 6 1 AAA domain AAA_18 PF13238.6 RLN94413.1 - 0.11 13.1 1.8 0.89 10.1 0.0 3.4 3 1 0 3 3 3 0 AAA domain DUF1953 PF09196.10 RLN94413.1 - 0.12 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1953) Hydin_ADK PF17213.3 RLN94413.1 - 0.42 10.9 0.0 0.42 10.9 0.0 3.4 3 1 0 3 3 3 0 Hydin Adenylate kinase-like domain Ribosomal_L13 PF00572.18 RLN94414.1 - 2.3e-53 179.7 0.0 2.8e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 Mito_carr PF00153.27 RLN94415.1 - 1.7e-59 197.8 0.7 5e-20 71.2 0.0 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein bcl-2I13 PF12201.8 RLN94415.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Bcl2-interacting killer, BH3-domain containing DUF1631 PF07793.11 RLN94416.1 - 0.0057 15.2 1.6 0.006 15.1 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1631) Dynein_C PF18199.1 RLN94417.1 - 9e-77 258.3 0.0 1.4e-76 257.7 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 RLN94417.1 - 1.3e-48 164.9 0.0 2.3e-48 164.1 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RLN94417.1 - 2.2e-34 118.1 0.0 7.1e-34 116.5 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_9 PF12781.7 RLN94417.1 - 1.7e-05 24.1 0.9 3.6e-05 23.0 0.6 1.7 2 0 0 2 2 2 1 ATP-binding dynein motor region DUF1168 PF06658.12 RLN94418.1 - 8.7e-16 58.0 39.4 9.6e-12 44.9 0.8 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1168) Rrn6 PF10214.9 RLN94418.1 - 0.0071 14.9 10.2 0.0083 14.7 10.2 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor ATP11 PF06644.11 RLN94418.1 - 1.9 8.2 13.4 2.7 7.7 13.4 1.3 1 0 0 1 1 1 0 ATP11 protein DUF913 PF06025.12 RLN94418.1 - 4.6 6.1 6.4 6.8 5.6 6.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PX PF00787.24 RLN94419.1 - 5.2e-13 49.0 0.0 1.2e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 PX domain Lipase_3 PF01764.25 RLN94419.1 - 5.5e-11 42.5 0.0 1.6e-10 41.0 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) Peptidase_M20 PF01546.28 RLN94420.1 - 1.3e-23 83.8 0.0 1.7e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 RLN94420.1 - 4.5e-12 45.8 0.0 2.3e-11 43.6 0.0 2.1 2 1 0 2 2 2 1 Peptidase dimerisation domain Pterin_4a PF01329.19 RLN94421.1 - 1.8e-25 88.9 0.1 2.6e-25 88.4 0.1 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Rhodanese PF00581.20 RLN94422.1 - 2.2e-10 41.0 0.1 3.9e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DUF3854 PF12965.7 RLN94422.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) Peptidase_S8 PF00082.22 RLN94423.1 - 1.9e-18 66.8 0.9 2.1e-18 66.6 0.9 1.0 1 0 0 1 1 1 1 Subtilase family PBCV_basic_adap PF08789.10 RLN94424.1 - 2.4e-05 24.3 0.6 8.1e-05 22.7 0.6 2.0 1 0 0 1 1 1 1 PBCV-specific basic adaptor domain Blo-t-5 PF11642.8 RLN94425.1 - 0.055 13.4 0.2 0.26 11.3 0.0 2.1 2 1 1 3 3 3 0 Mite allergen Blo t 5 PBCV_basic_adap PF08789.10 RLN94426.1 - 5.8e-06 26.3 6.5 0.014 15.5 0.4 3.1 1 1 2 3 3 3 2 PBCV-specific basic adaptor domain DUF1041 PF06292.17 RLN94426.1 - 0.5 10.8 3.1 1.5 9.3 0.1 2.5 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1041) GMC_oxred_N PF00732.19 RLN94427.1 - 5.6e-30 104.7 0.0 1.5e-29 103.3 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase PAN_4 PF14295.6 RLN94427.1 - 7.3e-17 61.0 13.0 3.4e-08 33.3 2.4 2.6 2 0 0 2 2 2 2 PAN domain PAN_1 PF00024.26 RLN94427.1 - 1.4e-10 41.0 4.9 7.8e-06 25.8 0.3 2.5 1 1 1 2 2 2 2 PAN domain GMC_oxred_C PF05199.13 RLN94427.1 - 2e-09 38.1 0.1 2e-09 38.1 0.1 2.1 3 0 0 3 3 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 RLN94427.1 - 8e-08 31.8 0.5 0.00051 19.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 RLN94427.1 - 5.5e-06 26.5 0.1 3e-05 24.1 0.0 2.5 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 RLN94427.1 - 6.2e-06 25.6 0.2 6.3e-05 22.3 0.2 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 RLN94427.1 - 0.00069 19.3 1.3 0.0045 16.6 1.3 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RLN94427.1 - 0.0044 16.3 0.1 0.021 14.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RLN94427.1 - 0.0046 16.2 0.1 0.007 15.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 RLN94427.1 - 0.019 14.0 0.3 0.057 12.5 0.3 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 RLN94427.1 - 0.14 11.4 0.3 0.35 10.1 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.20 RLN94428.1 - 1e-10 42.1 0.0 1.2e-10 41.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DNA_pol_E_B PF04042.16 RLN94429.1 - 1.6e-36 125.7 0.0 2.4e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 RLN94429.1 - 7.1e-29 100.5 0.0 1.3e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Rhodanese PF00581.20 RLN94430.1 - 5.2e-12 46.2 0.0 6.2e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF2525 PF10733.9 RLN94430.1 - 0.022 15.0 0.2 0.34 11.2 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2525) Peptidase_S9 PF00326.21 RLN94431.1 - 2.8e-23 82.5 0.0 8.4e-23 81.0 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 RLN94431.1 - 1.9e-12 46.8 1.2 4.5e-05 23.3 0.0 3.8 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.20 RLN94431.1 - 4.3e-08 33.1 0.3 7.9e-06 25.7 0.3 2.6 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN94431.1 - 0.0041 16.4 0.0 0.023 14.0 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 RLN94431.1 - 0.046 13.3 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Acyl_transf_3 PF01757.22 RLN94432.1 - 4.5e-09 35.8 40.7 6.4e-09 35.3 40.7 1.2 1 0 0 1 1 1 1 Acyltransferase family Peptidase_C48 PF02902.19 RLN94433.1 - 1.3e-06 28.5 0.0 2.1e-06 27.7 0.0 1.3 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain AMP-binding PF00501.28 RLN94435.1 - 1.9e-76 257.3 0.0 2.4e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN94435.1 - 0.00058 20.8 0.1 0.0016 19.4 0.1 1.9 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cyclophil_like2 PF18050.1 RLN94435.1 - 0.19 11.7 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Cyclophilin-like family Pkinase_Tyr PF07714.17 RLN94436.1 - 0.00039 19.8 0.0 0.00071 18.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.21 RLN94438.1 - 2.4e-14 53.2 13.2 5.1e-14 52.1 13.2 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN94438.1 - 0.11 12.7 9.0 0.24 11.6 8.1 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger AAA PF00004.29 RLN94439.1 - 6.5e-44 149.5 0.0 1.5e-43 148.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 RLN94439.1 - 1.6e-10 40.8 0.1 1e-09 38.2 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 RLN94439.1 - 8.5e-09 35.5 0.1 2.9e-08 33.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RLN94439.1 - 1e-07 32.2 0.1 2.9e-07 30.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 RLN94439.1 - 3.5e-06 26.7 0.0 8.5e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 RLN94439.1 - 1.5e-05 25.5 0.3 0.0022 18.4 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 RLN94439.1 - 0.00011 22.1 0.1 0.013 15.4 0.0 3.0 3 0 0 3 3 3 1 NTPase RuvB_N PF05496.12 RLN94439.1 - 0.00021 21.0 0.0 0.00061 19.6 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RLN94439.1 - 0.00025 21.3 0.7 0.022 15.0 0.7 2.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 RLN94439.1 - 0.00026 20.3 0.0 0.00054 19.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 RLN94439.1 - 0.00056 19.4 0.1 0.0013 18.1 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 RLN94439.1 - 0.00083 18.7 0.0 0.0018 17.6 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 RLN94439.1 - 0.00091 19.8 0.0 0.0027 18.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 RLN94439.1 - 0.0017 18.6 0.1 0.0057 16.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 RLN94439.1 - 0.0022 18.0 0.0 0.029 14.4 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 RLN94439.1 - 0.0023 18.2 0.0 0.0046 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 RLN94439.1 - 0.0036 17.0 0.0 0.0088 15.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 RLN94439.1 - 0.0041 16.6 0.1 0.017 14.7 0.1 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 RLN94439.1 - 0.0051 17.2 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 RLN94439.1 - 0.011 15.4 0.3 0.024 14.3 0.3 1.6 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 RLN94439.1 - 0.013 14.6 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 RLN94439.1 - 0.016 14.9 0.2 0.17 11.6 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 RLN94439.1 - 0.019 14.7 0.2 0.046 13.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 RLN94439.1 - 0.026 14.6 0.0 0.081 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RLN94439.1 - 0.029 14.3 0.1 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 RLN94439.1 - 0.058 13.3 0.1 1.1 9.1 0.0 2.4 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 RLN94439.1 - 0.069 12.5 0.0 1.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA_3 PF07726.11 RLN94439.1 - 0.074 12.9 0.1 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AFG1_ATPase PF03969.16 RLN94439.1 - 0.087 11.7 0.1 0.23 10.3 0.1 1.6 1 1 0 1 1 1 0 AFG1-like ATPase PhoH PF02562.16 RLN94439.1 - 0.11 12.0 0.1 0.26 10.7 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 RLN94439.1 - 0.12 11.6 0.7 1.2 8.4 0.0 2.6 3 0 0 3 3 3 0 KaiC AAA_25 PF13481.6 RLN94439.1 - 0.13 11.8 2.8 0.5 9.9 0.3 2.3 1 1 1 2 2 2 0 AAA domain HIP1_clath_bdg PF16515.5 RLN94439.1 - 0.17 12.5 0.3 1.9 9.1 0.1 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 COPI_assoc PF08507.10 RLN94440.1 - 5e-10 39.5 5.4 6e-10 39.3 5.4 1.1 1 0 0 1 1 1 1 COPI associated protein Tetraspanin PF00335.20 RLN94442.1 - 6e-08 32.7 4.9 1.5e-07 31.4 4.9 1.6 1 1 0 1 1 1 1 Tetraspanin family Baculo_p74_N PF08404.10 RLN94442.1 - 0.051 12.7 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal DUF4884 PF16225.5 RLN94443.1 - 0.73 10.0 4.3 13 5.9 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4884) NACHT PF05729.12 RLN94445.1 - 3.3e-08 33.6 0.1 6.7e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 RLN94445.1 - 0.00078 19.9 1.3 0.0036 17.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Dynamitin PF04912.14 RLN94445.1 - 0.0013 18.2 0.4 0.0022 17.4 0.4 1.4 1 0 0 1 1 1 1 Dynamitin AAA_22 PF13401.6 RLN94445.1 - 0.018 15.3 0.2 0.1 12.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 RLN94445.1 - 0.043 14.3 1.2 2.2 8.8 0.0 3.1 4 0 0 4 4 4 0 ABC transporter KORA PF16509.5 RLN94445.1 - 0.092 13.0 0.5 1.5 9.2 0.3 2.6 3 0 0 3 3 3 0 TrfB plasmid transcriptional repressor SPATA1_C PF15743.5 RLN94445.1 - 0.12 12.5 0.1 0.3 11.2 0.1 1.6 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus HGTP_anticodon2 PF12745.7 RLN94445.1 - 0.13 11.7 0.8 0.35 10.3 0.8 1.7 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs RE_EcoO109I PF14511.6 RLN94445.1 - 0.19 11.3 0.1 0.52 9.9 0.0 1.7 2 0 0 2 2 2 0 Type II restriction endonuclease EcoO109I Complex1_LYR PF05347.15 RLN94446.1 - 1.5e-06 28.1 0.1 3.4e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 RLN94446.1 - 0.0015 19.3 0.6 0.0021 18.7 0.6 1.6 1 1 0 1 1 1 1 Complex1_LYR-like ING PF12998.7 RLN94446.1 - 0.078 13.6 0.1 0.15 12.7 0.0 1.5 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding GPP34 PF05719.11 RLN94446.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.3 1 1 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) Pyr_redox_2 PF07992.14 RLN94447.1 - 5.9e-51 173.4 0.0 9.5e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 RLN94447.1 - 1.3e-21 76.9 0.0 2.8e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 RLN94447.1 - 4.8e-15 55.9 2.8 9.5e-13 48.5 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RLN94447.1 - 1.4e-14 54.1 0.1 2.8e-11 43.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 RLN94447.1 - 1.9e-06 27.2 0.9 6.1e-05 22.3 0.8 2.7 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 RLN94447.1 - 0.00056 19.3 0.0 0.8 9.0 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 RLN94447.1 - 0.0014 17.4 0.1 0.0094 14.7 0.1 2.3 3 1 1 4 4 4 1 HI0933-like protein Thi4 PF01946.17 RLN94447.1 - 0.0048 16.2 0.9 0.012 14.9 0.1 2.0 3 0 0 3 3 3 1 Thi4 family DAO PF01266.24 RLN94447.1 - 0.013 15.1 0.8 0.085 12.4 0.3 2.5 2 2 1 3 3 3 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 RLN94447.1 - 0.069 12.5 0.2 0.14 11.4 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 RLN94447.1 - 0.19 10.7 0.3 0.36 9.9 0.3 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 RLN94447.1 - 0.89 9.8 2.9 1.1 9.5 0.2 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain IQ PF00612.27 RLN94448.1 - 2.3e-06 26.9 3.0 0.00063 19.3 1.8 2.9 2 0 0 2 2 2 2 IQ calmodulin-binding motif PH PF00169.29 RLN94449.1 - 4.7e-06 27.1 0.0 9e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF5089 PF17002.5 RLN94449.1 - 0.024 14.5 2.5 0.27 11.1 2.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5089) SlyX PF04102.12 RLN94449.1 - 0.11 13.1 4.7 0.24 12.0 3.2 2.2 2 0 0 2 2 2 0 SlyX DUF812 PF05667.11 RLN94449.1 - 0.11 11.4 4.0 0.16 10.8 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TMF_TATA_bd PF12325.8 RLN94449.1 - 0.33 11.2 7.3 1.5 9.1 1.8 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Tropomyosin PF00261.20 RLN94449.1 - 1.7 7.9 11.3 0.056 12.8 2.3 2.3 3 0 0 3 3 3 0 Tropomyosin DUF1891 PF09004.10 RLN94452.1 - 0.41 10.3 2.7 0.65 9.6 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) PALP PF00291.25 RLN94453.1 - 2.4e-38 132.2 0.0 2.7e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cwf_Cwc_15 PF04889.12 RLN94454.1 - 0.0023 17.7 14.6 0.071 12.8 6.3 2.2 2 0 0 2 2 2 2 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 RLN94454.1 - 0.015 15.0 6.0 0.82 9.3 0.2 2.4 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.6 RLN94454.1 - 0.03 14.7 6.8 0.03 14.7 6.8 2.6 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 RLN94454.1 - 2 8.9 11.1 5 7.6 11.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 RLN94454.1 - 2.7 7.2 14.4 0.34 10.2 9.7 1.7 2 0 0 2 2 2 0 NOA36 protein Sigma70_ner PF04546.13 RLN94454.1 - 4 7.3 7.2 21 4.9 2.4 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4820 PF16091.5 RLN94454.1 - 5.3 6.3 7.6 5.4 6.3 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) RXT2_N PF08595.11 RLN94454.1 - 8.9 6.3 7.7 1.2 9.2 2.5 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal CKS PF01111.19 RLN94455.1 - 3.3e-29 100.9 5.3 2.4e-27 95.0 5.3 2.1 1 1 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Mito_carr PF00153.27 RLN94456.1 - 8.4e-64 211.6 2.6 2.1e-20 72.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Exo_endo_phos PF03372.23 RLN94457.1 - 6.3e-27 94.6 0.0 3.7e-26 92.1 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family fn3 PF00041.21 RLN94457.1 - 1.3e-11 44.7 0.0 2.6e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain MMTV_SAg PF01054.17 RLN94457.1 - 0.041 13.4 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen Pur_ac_phosph_N PF16656.5 RLN94457.1 - 0.062 13.9 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain tRNA-synt_2 PF00152.20 RLN94458.1 - 1.8e-81 273.7 0.0 2.1e-81 273.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RLN94458.1 - 2e-08 34.1 0.2 4.6e-08 32.9 0.2 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 RLN94458.1 - 0.0074 15.8 0.1 0.067 12.7 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) Met_10 PF02475.16 RLN94459.1 - 4.8e-64 215.8 0.0 7.7e-64 215.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein tRNA_U5-meth_tr PF05958.11 RLN94459.1 - 0.0012 17.9 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 RLN94459.1 - 0.0052 16.4 0.0 0.0099 15.5 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_23 PF13489.6 RLN94459.1 - 0.0075 16.1 0.0 0.076 12.8 0.0 2.2 1 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 RLN94459.1 - 0.031 13.8 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TRM PF02005.16 RLN94459.1 - 0.034 13.3 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase FmrO PF07091.11 RLN94459.1 - 0.05 13.2 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) D123 PF07065.14 RLN94459.1 - 0.11 11.6 0.2 0.3 10.2 0.1 1.7 2 0 0 2 2 2 0 D123 LAMTOR5 PF16672.5 RLN94462.1 - 0.021 14.8 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 PIH1 PF08190.12 RLN94463.1 - 2.3e-35 121.5 0.0 4.7e-35 120.5 0.0 1.6 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 RLN94463.1 - 3.4e-15 56.3 0.0 1.3e-14 54.4 0.0 2.0 2 0 0 2 2 2 1 PIH1 CS-like domain CS PF04969.16 RLN94463.1 - 0.0024 18.9 0.0 0.66 11.0 0.0 2.6 2 0 0 2 2 2 1 CS domain MethyTransf_Reg PF10119.9 RLN94463.1 - 0.037 14.7 0.0 5.1 7.9 0.0 2.8 2 0 0 2 2 2 0 Predicted methyltransferase regulatory domain WD40 PF00400.32 RLN94464.1 - 7.4e-10 39.3 12.1 0.098 13.6 1.2 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN94464.1 - 3.9e-06 27.1 0.0 0.33 11.3 0.0 4.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Coilin_N PF15862.5 RLN94464.1 - 1.2 8.9 9.5 2.8 7.7 9.5 1.6 1 0 0 1 1 1 0 Coilin N-terminus CDC45 PF02724.14 RLN94464.1 - 7.5 4.7 9.7 12 4.1 9.7 1.2 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpb6 PF01192.22 RLN94465.1 - 1.5e-16 60.0 0.3 2.6e-16 59.3 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 AAA_14 PF13173.6 RLN94465.1 - 0.14 12.2 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain EGF_2 PF07974.13 RLN94466.1 - 4.3e-14 52.6 67.4 5.3e-05 23.5 13.6 5.5 5 1 0 5 5 5 5 EGF-like domain Laminin_EGF PF00053.24 RLN94466.1 - 1.2 9.3 54.8 0.061 13.5 6.7 4.8 4 2 0 4 4 4 0 Laminin EGF domain Tektin PF03148.14 RLN94467.1 - 1.6 7.4 16.4 0.11 11.3 11.2 1.6 2 0 0 2 2 2 0 Tektin family TMF_TATA_bd PF12325.8 RLN94467.1 - 5.5 7.2 15.6 2 8.7 2.0 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF465 PF04325.13 RLN94467.1 - 7.1 6.8 10.3 0.21 11.7 0.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF465) RRM_1 PF00076.22 RLN94468.1 - 5.1e-18 64.7 0.0 9.2e-18 63.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DAD PF02109.16 RLN94469.1 - 1.5e-38 131.4 3.2 3.5e-23 82.0 0.9 2.1 2 0 0 2 2 2 2 DAD family ETF PF01012.21 RLN94470.1 - 6.2e-15 55.5 5.8 6.7e-15 55.4 5.8 1.0 1 0 0 1 1 1 1 Electron transfer flavoprotein domain TolA PF06519.11 RLN94472.1 - 0.068 13.4 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 TolA C-terminal Uteroglobin PF01099.17 RLN94475.1 - 0.0077 16.5 0.1 2.6 8.5 0.1 3.0 2 0 0 2 2 2 2 Uteroglobin family HisKA_2 PF07568.12 RLN94475.1 - 1.2 9.2 4.3 1.1 9.4 0.5 2.6 2 0 0 2 2 2 0 Histidine kinase MGC-24 PF05283.11 RLN94476.1 - 0.34 11.3 7.8 0.76 10.2 7.8 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FSA_C PF10479.9 RLN94476.1 - 7.9 4.5 8.8 12 3.8 8.8 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Sld5 PF05916.11 RLN94477.1 - 2.6e-09 37.5 0.0 4.1e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein VWA_2 PF13519.6 RLN94478.1 - 1.2e-11 45.2 0.1 9.4e-11 42.3 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 RLN94478.1 - 0.0006 20.1 0.0 0.0016 18.7 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain INT_SG_DDX_CT_C PF15300.6 RLN94478.1 - 0.011 15.5 1.8 0.47 10.3 0.1 2.9 3 0 0 3 3 3 0 INTS6/SAGE1/DDX26B/CT45 C-terminus DHC_N2 PF08393.13 RLN94479.1 - 4.3e-130 434.4 7.9 4.3e-130 434.4 7.9 2.0 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AHSA1 PF08327.11 RLN94479.1 - 0.13 12.5 0.5 2.1 8.6 0.1 2.6 2 0 0 2 2 2 0 Activator of Hsp90 ATPase homolog 1-like protein UDPGP PF01704.18 RLN94480.1 - 9.5e-51 172.7 0.0 1.4e-49 168.8 0.0 2.0 2 0 0 2 2 2 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 RLN94480.1 - 0.017 15.5 0.0 0.046 14.1 0.0 1.8 1 0 0 1 1 1 0 MobA-like NTP transferase domain RRM_4 PF10598.9 RLN94480.1 - 0.093 13.1 0.0 4.3 7.7 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif of the spliceosomal PrP8 SAP PF02037.27 RLN94481.1 - 6.9e-07 28.9 0.4 6.9e-07 28.9 0.4 2.4 3 0 0 3 3 3 1 SAP domain RRM_1 PF00076.22 RLN94481.1 - 4.2e-05 23.3 0.1 8.9e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_C10 PF01640.17 RLN94481.1 - 0.4 11.0 1.7 0.55 10.5 1.3 1.5 1 1 0 1 1 1 0 Peptidase C10 family Spem1 PF15670.5 RLN94481.1 - 2.7 7.5 10.8 3.7 7.0 10.8 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 OHCU_decarbox PF09349.10 RLN94482.1 - 1e-31 110.5 0.1 1.3e-31 110.2 0.1 1.0 1 0 0 1 1 1 1 OHCU decarboxylase UDPGP PF01704.18 RLN94483.1 - 8.1e-44 149.9 0.0 1.1e-43 149.5 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 RLN94483.1 - 0.066 13.6 0.1 0.15 12.5 0.1 1.8 1 1 0 1 1 1 0 MobA-like NTP transferase domain SNF2_N PF00176.23 RLN94484.1 - 3.7e-62 210.1 0.0 5.5e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN94484.1 - 3.9e-08 33.6 0.0 8.3e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TOBE_3 PF12857.7 RLN94484.1 - 0.013 15.4 0.1 27 4.8 0.0 3.6 3 0 0 3 3 3 0 TOBE-like domain F-box_4 PF15966.5 RLN94484.1 - 0.016 15.1 0.1 0.036 13.9 0.1 1.6 1 0 0 1 1 1 0 F-box ResIII PF04851.15 RLN94484.1 - 0.058 13.4 0.0 9 6.3 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 RLN94484.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase F-box-like PF12937.7 RLN94484.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 F-box-like Nop14 PF04147.12 RLN94484.1 - 1.7 6.8 5.4 2.5 6.2 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family FA_hydroxylase PF04116.13 RLN94485.1 - 1.4e-21 77.2 24.9 1.4e-21 77.2 24.9 1.9 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily HMA PF00403.26 RLN94486.1 - 1.7e-11 44.4 0.5 2e-11 44.2 0.5 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain MPS-4 PF17523.2 RLN94487.1 - 0.099 12.8 3.0 8.6 6.6 0.1 3.7 2 0 0 2 2 2 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 DUF3697 PF12478.8 RLN94487.1 - 0.16 12.1 0.2 0.37 10.9 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-associated protein 2 Asp_Arg_Hydrox PF05118.15 RLN94488.1 - 3.5e-43 147.2 2.3 4.8e-43 146.7 2.3 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase AraC_binding PF02311.19 RLN94488.1 - 0.041 13.8 0.0 0.09 12.7 0.0 1.8 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_2 PF07883.11 RLN94488.1 - 0.057 13.1 0.0 0.057 13.1 0.0 2.0 3 0 0 3 3 3 0 Cupin domain SNF2_N PF00176.23 RLN94489.1 - 1.6e-62 211.3 0.0 2.8e-62 210.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN94489.1 - 2.5e-10 40.7 0.0 6.1e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 RLN94489.1 - 8.9e-06 25.5 9.9 1.8e-05 24.5 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN94489.1 - 0.0011 18.7 8.4 0.0011 18.7 8.4 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN94489.1 - 0.0026 17.7 9.9 0.0061 16.5 9.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain DUF2726 PF10881.8 RLN94489.1 - 0.0043 16.9 2.9 0.17 11.8 0.4 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2726) F-box-like PF12937.7 RLN94489.1 - 0.006 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like ERCC3_RAD25_C PF16203.5 RLN94489.1 - 0.022 13.9 0.0 0.049 12.8 0.0 1.6 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase F-box PF00646.33 RLN94489.1 - 0.025 14.5 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 F-box domain zf-C3HC4 PF00097.25 RLN94489.1 - 0.034 14.0 10.3 0.066 13.1 10.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) F-box_4 PF15966.5 RLN94489.1 - 0.039 13.8 0.1 0.095 12.6 0.1 1.6 1 0 0 1 1 1 0 F-box zf-C3HC4_2 PF13923.6 RLN94489.1 - 0.41 10.5 11.1 0.95 9.4 11.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RLN94489.1 - 1.1 9.5 9.5 2.5 8.3 9.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING LRS4 PF10422.9 RLN94489.1 - 1.1 8.8 8.6 5.9 6.4 3.6 2.6 2 1 0 2 2 2 0 Monopolin complex subunit LRS4 zf-RING_UBOX PF13445.6 RLN94489.1 - 2.9 8.0 9.8 5.9 7.0 9.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 RLN94489.1 - 4.1 7.8 14.1 1.3 9.4 10.8 1.9 2 0 0 2 2 2 0 Ring finger domain His_Phos_2 PF00328.22 RLN94491.1 - 4.8e-29 101.9 0.0 6.6e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF5343 PF17278.2 RLN94491.1 - 0.17 11.9 0.0 0.53 10.4 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5343) Lipoxygenase PF00305.19 RLN94492.1 - 3.2e-07 29.2 0.1 4.4e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 Lipoxygenase LIAS_N PF16881.5 RLN94493.1 - 0.018 15.5 0.1 0.027 14.9 0.1 1.4 1 1 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family Ribosomal_S7e PF01251.18 RLN94494.1 - 1.5e-83 279.1 2.6 1.7e-83 278.9 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Pyr_redox_2 PF07992.14 RLN94495.1 - 1.9e-40 139.0 0.0 2.8e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RLN94495.1 - 0.0002 21.8 0.4 0.017 15.7 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 RLN94495.1 - 0.12 12.4 0.0 6.1 6.8 0.0 3.0 3 1 1 4 4 4 0 FAD-NAD(P)-binding OB_Dis3 PF17849.1 RLN94496.1 - 1.2e-16 60.4 0.0 2.6e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 RLN94496.1 - 1.2e-13 51.1 0.0 2.1e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Rrp44-like cold shock domain Pept_tRNA_hydro PF01195.19 RLN94497.1 - 0.0011 19.0 0.3 0.0055 16.7 0.1 1.7 1 1 1 2 2 2 1 Peptidyl-tRNA hydrolase DDE_3 PF13358.6 RLN94497.1 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease SWIM PF04434.17 RLN94498.1 - 4.9e-05 22.9 0.1 0.00014 21.5 0.1 1.7 1 0 0 1 1 1 1 SWIM zinc finger MULE PF10551.9 RLN94498.1 - 0.00014 22.3 0.0 0.00034 21.0 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Eco57I PF07669.11 RLN94499.1 - 0.082 13.4 0.4 0.23 12.0 0.4 1.8 1 0 0 1 1 1 0 Eco57I restriction-modification methylase Cnd1 PF12717.7 RLN94500.1 - 1.3e-19 70.9 0.7 1.4e-18 67.5 0.1 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 RLN94500.1 - 0.00014 21.2 0.5 0.00035 19.9 0.5 1.6 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain Pcc1 PF09341.10 RLN94502.1 - 0.042 14.0 0.0 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 Transcription factor Pcc1 DUF2505 PF10698.9 RLN94502.1 - 0.058 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) PGA2 PF07543.12 RLN94504.1 - 0.24 11.4 12.0 0.036 14.0 2.7 2.5 2 0 0 2 2 2 0 Protein trafficking PGA2 OrfB_Zn_ribbon PF07282.11 RLN94506.1 - 0.00031 20.6 0.2 0.00068 19.5 0.2 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 RLN94507.1 - 0.0048 17.1 0.8 0.0048 17.1 0.8 2.5 2 0 0 2 2 2 1 Probable transposase OrfB_Zn_ribbon PF07282.11 RLN94507.1 - 0.11 12.4 0.2 0.52 10.3 0.0 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain E7 PF00527.18 RLN94507.1 - 0.32 11.2 2.4 22 5.3 0.6 2.9 2 0 0 2 2 2 0 E7 protein, Early protein CENP-B_dimeris PF09026.10 RLN94507.1 - 1.3 9.5 6.3 3.9 7.9 6.3 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Spt5_N PF11942.8 RLN94507.1 - 2.3 9.3 12.7 0.1 13.6 5.3 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PRR20 PF15708.5 RLN94507.1 - 2.7 7.8 8.8 5.2 6.9 8.8 1.4 1 0 0 1 1 1 0 Proline-rich protein family 20 CDC45 PF02724.14 RLN94507.1 - 3.7 5.7 13.0 6.2 5.0 6.1 2.3 2 0 0 2 2 2 0 CDC45-like protein Choline_transpo PF04515.12 RLN94510.1 - 3e-89 299.4 31.6 3e-89 299.4 31.6 1.8 2 0 0 2 2 2 1 Plasma-membrane choline transporter CBFD_NFYB_HMF PF00808.23 RLN94510.1 - 9.3e-22 77.1 2.8 1.2e-21 76.7 1.1 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 RLN94510.1 - 2.8e-16 60.0 1.7 5.4e-16 59.1 1.7 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TPT PF03151.16 RLN94511.1 - 6.4e-39 134.0 15.9 7.9e-39 133.7 15.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 RLN94511.1 - 5.8e-08 33.0 20.4 0.00023 21.4 3.8 2.0 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 RLN94511.1 - 1.7e-05 24.2 15.3 0.00011 21.5 15.3 1.9 1 1 0 1 1 1 1 UAA transporter family DUF2933 PF11666.8 RLN94511.1 - 0.13 12.3 1.0 0.25 11.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2933) DUF2633 PF11119.8 RLN94511.1 - 0.99 9.4 3.1 12 5.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2633) YbjQ_1 PF01906.17 RLN94512.1 - 3.1e-16 59.9 4.5 3.8e-11 43.5 0.3 3.4 2 1 1 3 3 3 2 Putative heavy-metal-binding HemY_N PF07219.13 RLN94512.1 - 0.03 14.5 0.4 0.03 14.5 0.4 3.0 2 1 0 2 2 2 0 HemY protein N-terminus NusB PF01029.18 RLN94512.1 - 0.69 10.2 3.4 3.6 7.8 0.2 2.7 2 0 0 2 2 2 0 NusB family Pro_dh-DNA_bdg PF14850.6 RLN94513.1 - 0.018 15.6 0.3 1.9 9.0 0.0 3.1 3 1 0 3 3 3 0 DNA-binding domain of Proline dehydrogenase Tox-ODYAM1 PF15642.6 RLN94513.1 - 2.3 7.1 8.0 0.083 11.8 1.0 1.8 2 0 0 2 2 2 0 Toxin in Odyssella and Amoebophilus Myosin_head PF00063.21 RLN94514.1 - 4e-154 514.5 0.0 1e-153 513.1 0.0 1.6 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 RLN94514.1 - 0.0039 17.5 0.6 0.049 13.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RLN94514.1 - 0.0048 16.2 0.5 0.012 14.9 0.5 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 RLN94514.1 - 0.0089 16.4 0.1 0.027 14.8 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain Myosin_N PF02736.19 RLN94514.1 - 0.013 15.3 0.1 0.024 14.4 0.1 1.4 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain RNA_helicase PF00910.22 RLN94514.1 - 0.044 14.2 0.1 0.096 13.1 0.1 1.6 1 0 0 1 1 1 0 RNA helicase UBA PF00627.31 RLN94515.1 - 4.1e-09 36.2 1.1 8.8e-09 35.1 0.2 2.1 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.6 RLN94515.1 - 0.00047 19.9 0.1 0.00096 18.9 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain CUE PF02845.16 RLN94515.1 - 0.0092 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 CUE domain DUF4971 PF16341.5 RLN94516.1 - 0.024 14.4 0.2 0.062 13.1 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) Pkinase PF00069.25 RLN94517.1 - 1.6e-31 109.6 0.0 2.4e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN94517.1 - 2.9e-30 105.4 0.0 4e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Metallothio PF00131.20 RLN94518.1 - 1.6 9.0 9.6 2.4 8.3 9.6 1.3 1 0 0 1 1 1 0 Metallothionein FAR1 PF03101.15 RLN94519.1 - 0.00071 20.2 0.0 0.0011 19.6 0.0 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.11 RLN94519.1 - 0.12 12.8 0.3 3.2 8.2 0.1 2.5 2 1 1 3 3 3 0 Transcription factor AFT GFO_IDH_MocA PF01408.22 RLN94520.1 - 6.6e-25 88.3 0.1 8e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.6 RLN94520.1 - 3.8e-06 27.3 0.1 1.2e-05 25.7 0.0 1.7 1 1 1 2 2 2 1 Putative NAD(P)-binding F420_oxidored PF03807.17 RLN94520.1 - 8.8e-06 26.2 0.1 1.4e-05 25.5 0.1 1.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 RLN94520.1 - 0.0013 18.9 0.0 0.0027 17.9 0.0 1.3 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 RLN94520.1 - 0.0027 17.1 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 RLN94520.1 - 0.0059 16.7 0.1 0.059 13.4 0.0 2.1 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 RLN94520.1 - 0.024 14.9 1.7 1.1 9.5 0.3 2.1 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Rossmann-like PF10727.9 RLN94520.1 - 0.038 13.9 0.9 0.058 13.3 0.9 1.5 1 1 0 1 1 1 0 Rossmann-like domain NAD_binding_3 PF03447.16 RLN94520.1 - 0.063 13.9 0.1 0.085 13.5 0.1 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CoA_binding PF02629.19 RLN94520.1 - 0.088 13.5 1.3 1.1 10.0 0.1 2.4 1 1 1 2 2 2 0 CoA binding domain ApbA PF02558.16 RLN94520.1 - 0.12 12.0 0.6 0.46 10.1 0.6 1.9 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 RLN94520.1 - 0.13 12.1 2.5 0.27 11.1 2.1 1.8 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 RLN94520.1 - 0.21 11.2 1.8 9.8 5.7 0.1 2.1 1 1 1 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain IQ PF00612.27 RLN94521.1 - 1.1e-05 24.8 0.7 0.012 15.3 0.0 2.9 2 0 0 2 2 2 2 IQ calmodulin-binding motif Tup_N PF08581.10 RLN94521.1 - 0.09 13.1 0.2 0.09 13.1 0.2 3.3 2 0 0 2 2 2 0 Tup N-terminal DUF2937 PF11157.8 RLN94521.1 - 1.3 8.8 12.5 0.13 12.0 2.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) DDE_Tnp_4 PF13359.6 RLN94523.1 - 0.029 14.1 0.1 0.13 11.9 0.1 1.9 1 1 0 1 1 1 0 DDE superfamily endonuclease LRR_8 PF13855.6 RLN94526.1 - 9.5e-07 28.5 0.5 2.6e-06 27.1 0.1 2.0 2 0 0 2 2 2 1 Leucine rich repeat SR-25 PF10500.9 RLN94527.1 - 0.015 14.9 10.4 0.022 14.4 10.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PAT1 PF09770.9 RLN94528.1 - 3.8 5.6 5.7 3.1 6.0 0.3 2.6 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 PIG-S PF10510.9 RLN94529.1 - 7e-107 358.4 1.4 8.1e-107 358.2 1.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein LINES_C PF14695.6 RLN94529.1 - 0.07 12.6 0.2 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 Lines C-terminus DUF3209 PF11483.8 RLN94529.1 - 0.083 13.3 0.5 0.26 11.7 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) Pico_P1A PF02226.16 RLN94530.1 - 3.7e-06 26.9 0.0 1.1 9.3 0.0 4.1 4 0 0 4 4 4 2 Picornavirus coat protein (VP4) DUF973 PF06157.11 RLN94530.1 - 0.00013 21.2 0.0 2.1 7.3 0.0 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF973) FliE PF02049.18 RLN94530.1 - 0.011 15.8 0.1 9.6 6.4 0.0 2.6 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE Lyase_8_C PF02884.17 RLN94530.1 - 0.095 13.2 0.1 2.4e+02 2.3 0.0 5.1 6 0 0 6 6 6 0 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Kazal_2 PF07648.15 RLN94530.1 - 0.39 10.9 12.6 8.9 6.5 0.5 4.4 3 0 0 3 3 3 0 Kazal-type serine protease inhibitor domain zf-C2HC_2 PF13913.6 RLN94530.1 - 2.1 8.4 8.8 19 5.3 0.2 4.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type CRAL_TRIO PF00650.20 RLN94531.1 - 6.6e-19 68.2 0.0 1.1e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain PH PF00169.29 RLN94531.1 - 0.00015 22.2 0.0 0.0003 21.3 0.0 1.5 1 0 0 1 1 1 1 PH domain CRAL_TRIO_2 PF13716.6 RLN94531.1 - 0.00055 20.1 0.0 0.0055 16.9 0.0 2.2 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain WD40 PF00400.32 RLN94532.1 - 2.9e-23 81.7 18.3 0.0003 21.5 0.2 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN94532.1 - 2.7e-10 40.4 0.7 0.002 18.4 0.0 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RLN94532.1 - 0.014 15.2 0.2 0.33 10.8 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Snf7 PF03357.21 RLN94534.1 - 1.4e-39 135.4 13.5 1.4e-39 135.4 13.5 1.9 1 1 1 2 2 2 1 Snf7 Phage_TAC_5 PF08890.11 RLN94534.1 - 0.0074 16.3 0.6 0.013 15.5 0.6 1.3 1 0 0 1 1 1 1 Phage XkdN-like tail assembly chaperone protein, TAC CCDC24 PF15669.5 RLN94534.1 - 0.013 15.3 2.6 0.017 15.0 0.6 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family zf-C3H2C3 PF17122.5 RLN94535.1 - 0.064 13.3 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger Pkinase PF00069.25 RLN94536.1 - 1.3e-51 175.5 0.0 1.7e-51 175.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN94536.1 - 3.4e-22 79.0 0.0 6.2e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN94536.1 - 7.9e-05 22.7 2.2 8.7e-05 22.6 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN94536.1 - 0.00047 19.6 0.1 0.00075 18.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RLN94536.1 - 0.004 16.1 0.1 0.0062 15.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 RLN94536.1 - 0.007 15.2 0.0 0.01 14.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 RLN94536.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 RLN94536.1 - 0.02 14.2 0.0 0.056 12.8 0.0 1.7 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 RLN94536.1 - 0.079 12.6 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Ribosomal_S9 PF00380.19 RLN94537.1 - 1.6e-48 164.2 0.0 2.6e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 HemY_N PF07219.13 RLN94540.1 - 0.1 12.8 0.4 0.1 12.8 0.4 1.8 1 1 1 2 2 2 0 HemY protein N-terminus Phage_holin_3_6 PF07332.11 RLN94540.1 - 0.18 11.8 4.4 0.2 11.7 4.4 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III FeoB_associated PF12669.7 RLN94540.1 - 0.28 11.6 0.3 0.28 11.6 0.3 1.6 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein DUF4131 PF13567.6 RLN94540.1 - 0.33 10.6 2.7 0.33 10.6 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) IPTL-CTERM PF18203.1 RLN94540.1 - 6.8 6.7 7.5 1.9 8.5 4.5 1.7 2 0 0 2 2 2 0 IPTL-CTERM motif Trp_oprn_chp PF09534.10 RLN94541.1 - 0.012 15.4 2.8 0.067 13.0 0.1 2.4 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4536 PF15055.6 RLN94541.1 - 4.2 7.7 4.6 2.4 8.5 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4536) cobW PF02492.19 RLN94542.1 - 2.7e-40 137.8 0.0 4e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 RLN94542.1 - 1.7e-18 66.3 0.1 3.4e-18 65.3 0.1 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 RLN94542.1 - 3.3e-05 23.9 0.1 0.21 11.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 RLN94542.1 - 0.00021 21.7 0.5 0.00074 19.9 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.27 RLN94542.1 - 0.0038 16.8 0.2 0.49 9.9 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain TsaE PF02367.17 RLN94542.1 - 0.0041 17.1 0.1 0.0098 15.9 0.1 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE CbtA PF09490.10 RLN94542.1 - 0.023 14.5 0.8 0.048 13.4 0.8 1.5 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) AAA_22 PF13401.6 RLN94542.1 - 0.039 14.2 2.2 0.43 10.9 2.7 2.5 2 1 1 3 3 2 0 AAA domain LapA_dom PF06305.11 RLN94542.1 - 0.056 13.3 1.2 0.13 12.1 1.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MMR_HSR1 PF01926.23 RLN94542.1 - 0.087 12.9 0.1 0.9 9.6 0.1 2.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 RLN94542.1 - 0.096 12.7 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_5 PF07728.14 RLN94542.1 - 0.1 12.6 0.1 11 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Pox_vIL-18BP PF05566.12 RLN94542.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Orthopoxvirus interleukin 18 binding protein TMEM100 PF16311.5 RLN94542.1 - 0.14 11.7 0.8 0.27 10.8 0.8 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 DUF4175 PF13779.6 RLN94542.1 - 0.21 9.4 0.5 0.32 8.9 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF2244 PF10003.9 RLN94542.1 - 0.27 10.9 2.8 0.53 9.9 2.8 1.5 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) AAA_29 PF13555.6 RLN94542.1 - 0.35 10.7 1.1 1 9.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Arf PF00025.21 RLN94542.1 - 0.43 10.0 1.8 16 4.9 0.1 2.4 2 1 0 2 2 2 0 ADP-ribosylation factor family Pkinase PF00069.25 RLN94544.1 - 5.8e-47 160.3 0.0 5e-40 137.5 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN94544.1 - 7.3e-30 104.1 0.0 2.6e-24 85.9 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase zf-B_box PF00643.24 RLN94544.1 - 9.9e-05 22.4 6.6 0.00027 21.0 6.6 1.7 1 0 0 1 1 1 1 B-box zinc finger Pkinase_fungal PF17667.1 RLN94544.1 - 0.00064 18.6 0.0 0.0017 17.2 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase CEBP_ZZ PF16366.5 RLN94544.1 - 0.0016 18.6 4.0 0.0035 17.5 4.0 1.5 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain Seadorna_VP7 PF07387.11 RLN94544.1 - 0.0021 17.2 0.3 0.0032 16.6 0.3 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 SAM_2 PF07647.17 RLN94544.1 - 0.008 16.3 0.1 0.017 15.2 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RLN94544.1 - 0.038 14.4 0.2 0.08 13.4 0.2 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) zf-AN1 PF01428.16 RLN94544.1 - 0.79 9.9 6.6 2.4 8.4 6.6 1.9 1 0 0 1 1 1 0 AN1-like Zinc finger CutA1 PF03091.15 RLN94545.1 - 0.02 14.8 0.0 0.062 13.2 0.0 1.8 1 1 1 2 2 2 0 CutA1 divalent ion tolerance protein GST_N_3 PF13417.6 RLN94547.1 - 1.1e-14 54.6 0.0 3.3e-12 46.6 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RLN94547.1 - 1.8e-12 47.4 0.0 4.7e-12 46.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN94547.1 - 4.5e-08 33.3 0.0 1.3e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RLN94547.1 - 5.5e-07 29.7 0.3 1.2e-06 28.6 0.2 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RLN94547.1 - 6.3e-05 23.1 0.1 0.00013 22.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RLN94547.1 - 0.00055 19.9 0.1 0.0012 18.8 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RLN94548.1 - 1.8e-11 44.2 0.0 7.6e-11 42.2 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 RLN94548.1 - 1.6e-10 41.3 0.0 1.4e-07 31.9 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RLN94548.1 - 4.9e-06 26.7 0.0 1.2e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RLN94548.1 - 6.5e-05 23.1 0.4 0.00049 20.3 0.2 2.4 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RLN94548.1 - 0.00018 21.7 0.0 0.00049 20.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN94548.1 - 0.009 16.0 1.0 0.019 15.0 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain MMR_HSR1 PF01926.23 RLN94549.1 - 4.9e-10 39.5 0.1 0.0016 18.5 0.0 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RLN94549.1 - 5.7e-05 22.7 0.1 1.7 8.2 0.0 3.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RLN94549.1 - 0.00015 21.7 0.1 0.00039 20.4 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 RLN94549.1 - 0.00041 20.5 1.3 0.003 17.6 1.3 2.3 1 1 0 1 1 1 1 Dynamin family Spore_IV_A PF09547.10 RLN94549.1 - 0.0067 15.4 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Stage IV sporulation protein A (spore_IV_A) AAA_14 PF13173.6 RLN94549.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 RLN94549.1 - 0.016 14.8 0.0 1.7 8.2 0.0 2.4 2 0 0 2 2 2 0 Ras family AAA_15 PF13175.6 RLN94549.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 RLN94549.1 - 0.04 13.2 0.0 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 Septin Roc PF08477.13 RLN94549.1 - 0.045 14.0 0.0 0.6 10.4 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 RLN94549.1 - 0.051 13.3 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 RLN94549.1 - 0.052 13.9 0.0 0.099 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 RLN94549.1 - 0.068 12.7 0.6 2.5 7.6 0.0 3.1 3 0 0 3 3 3 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 RLN94549.1 - 0.093 12.5 0.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 RLN94549.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 RLN94549.1 - 0.13 12.7 0.0 1.5 9.3 0.0 2.3 2 0 0 2 2 2 0 RNA helicase MeaB PF03308.16 RLN94549.1 - 0.14 11.1 0.1 3.4 6.6 0.0 2.2 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GST_N_3 PF13417.6 RLN94550.1 - 7.6e-12 45.5 0.0 1.5e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RLN94550.1 - 1.9e-10 40.9 0.0 3e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RLN94550.1 - 1.9e-05 24.8 0.0 3.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RLN94550.1 - 3.8e-05 23.8 0.0 6.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RLN94550.1 - 0.00028 21.1 0.0 0.00052 20.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN94550.1 - 0.00098 19.1 0.1 0.0027 17.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 RLN94550.1 - 0.046 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Hist_deacetyl PF00850.19 RLN94551.1 - 4.3e-80 269.5 0.0 5.8e-80 269.0 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain HD_assoc PF13286.6 RLN94551.1 - 0.02 15.4 0.0 0.041 14.4 0.0 1.6 1 0 0 1 1 1 0 Phosphohydrolase-associated domain Ribosom_S12_S23 PF00164.25 RLN94552.1 - 3.6e-49 165.1 0.9 5.9e-49 164.4 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Atx10homo_assoc PF09759.9 RLN94553.1 - 0.056 13.5 1.7 0.14 12.2 1.7 1.7 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain DUF3138 PF11336.8 RLN94553.1 - 0.19 10.3 1.1 0.35 9.4 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF1640 PF07798.11 RLN94553.1 - 0.88 9.6 11.2 1.2 9.2 3.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) HALZ PF02183.18 RLN94553.1 - 2.2 8.6 7.5 2.7 8.3 1.8 3.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 RLN94553.1 - 4.5 7.4 16.4 0.46 10.6 3.1 4.1 4 0 0 4 4 4 0 bZIP transcription factor GIT_CC PF16559.5 RLN94553.1 - 6.3 6.7 14.7 3.5 7.6 1.0 3.1 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor PhoD PF09423.10 RLN94554.1 - 4.5e-16 58.8 1.5 3.3e-15 56.0 1.5 2.2 1 1 0 1 1 1 1 PhoD-like phosphatase DUF5392 PF17370.2 RLN94554.1 - 0.035 14.2 0.1 0.073 13.1 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5392) SKG6 PF08693.10 RLN94554.1 - 0.14 11.6 1.2 0.28 10.6 1.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PDEase_I PF00233.19 RLN94555.1 - 4.5e-69 232.8 0.6 7.2e-69 232.1 0.6 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase tRNA-synt_2c PF01411.19 RLN94556.1 - 2.6e-204 679.8 0.0 3.4e-204 679.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 RLN94556.1 - 1.3e-15 57.2 0.0 3.8e-15 55.7 0.0 1.9 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 RLN94556.1 - 1.1e-09 38.8 5.4 3.4e-09 37.2 5.4 1.9 1 0 0 1 1 1 1 DHHA1 domain BLOC1_2 PF10046.9 RLN94556.1 - 0.13 12.6 0.4 3.4 8.0 0.0 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PARP PF00644.20 RLN94557.1 - 2.2e-09 37.2 0.8 0.00041 20.0 0.0 2.6 3 0 0 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain Thioredoxin_6 PF13848.6 RLN94558.1 - 3.1e-08 33.8 0.0 0.002 18.1 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.20 RLN94558.1 - 1e-06 28.7 0.0 0.4 10.7 0.0 4.8 5 0 0 5 5 5 2 Thioredoxin FliT PF05400.13 RLN94558.1 - 0.011 16.6 0.9 0.028 15.2 0.9 1.7 1 0 0 1 1 1 0 Flagellar protein FliT PRTP PF01366.18 RLN94558.1 - 0.12 10.4 1.5 0.16 10.0 1.5 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein YebO PF13974.6 RLN94558.1 - 3.3 7.8 8.4 2.7 8.1 6.3 1.9 2 0 0 2 2 2 0 YebO-like protein GST_N_3 PF13417.6 RLN94559.1 - 1.7e-10 41.1 0.0 4.9e-10 39.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RLN94559.1 - 2.3e-09 37.5 0.0 1.7e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RLN94559.1 - 1e-05 25.6 0.0 1.6e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RLN94559.1 - 1.2e-05 25.5 0.0 4.1e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN94559.1 - 0.0054 16.7 0.0 0.012 15.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RLN94559.1 - 0.031 14.5 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TagF_N PF09867.9 RLN94559.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 TagF N-terminal domain, Type VI secretion system-associated XPG_N PF00752.17 RLN94560.1 - 0.077 13.5 0.1 0.12 12.8 0.1 1.2 1 0 0 1 1 1 0 XPG N-terminal domain GST_N PF02798.20 RLN94561.1 - 1.5e-06 28.5 0.0 1.1e-05 25.7 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RLN94561.1 - 2.2e-06 27.8 0.0 3.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RLN94561.1 - 0.00042 20.7 0.0 0.00082 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN94561.1 - 0.0039 17.4 0.0 0.017 15.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN94561.1 - 0.0068 16.4 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RLN94561.1 - 0.0089 16.2 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Acyltransferase PF01553.21 RLN94562.1 - 7.7e-17 61.2 0.0 3.9e-16 58.9 0.0 2.1 2 0 0 2 2 2 1 Acyltransferase DUF3007 PF11460.8 RLN94562.1 - 0.08 13.2 0.0 13 6.1 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) RHD3 PF05879.12 RLN94563.1 - 2.2e-06 26.2 3.0 4.3e-06 25.2 0.0 2.1 2 0 0 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 RLN94563.1 - 2.1e-05 23.9 0.0 4.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain FANCI_S2 PF14676.6 RLN94563.1 - 0.019 15.3 0.0 15 5.8 0.0 3.0 3 0 0 3 3 3 0 FANCI solenoid 2 Dynamin_N PF00350.23 RLN94563.1 - 0.072 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Dynamin family MMR_HSR1 PF01926.23 RLN94563.1 - 0.079 13.0 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF1344 PF07076.11 RLN94563.1 - 0.13 12.2 0.2 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) Sds3 PF08598.11 RLN94563.1 - 0.81 9.6 2.6 12 5.8 0.1 2.6 2 0 0 2 2 2 0 Sds3-like PKD_channel PF08016.12 RLN94564.1 - 3.1e-16 59.1 12.1 5.2e-16 58.3 12.1 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 RLN94564.1 - 3.2e-08 33.1 10.5 5.6e-08 32.3 10.5 1.4 1 0 0 1 1 1 1 Ion transport protein NVEALA PF14055.6 RLN94564.1 - 0.94 9.5 6.8 31 4.7 0.3 4.1 5 0 0 5 5 5 0 NVEALA protein DEAD PF00270.29 RLN94565.1 - 2.9e-37 128.1 0.0 4.6e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN94565.1 - 2.2e-29 102.0 0.0 4.9e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN94565.1 - 1.9e-06 28.0 0.0 3.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RLN94565.1 - 0.00037 20.8 0.1 0.0036 17.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain PhosphMutase PF10143.9 RLN94566.1 - 3.8e-48 163.6 0.0 5.5e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 RLN94566.1 - 2.6e-28 99.1 0.0 3.3e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 RLN94566.1 - 1.9e-05 24.5 0.0 3.5e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Alk_phosphatase PF00245.20 RLN94566.1 - 0.0096 14.9 0.4 0.014 14.3 0.4 1.1 1 0 0 1 1 1 1 Alkaline phosphatase RNA_pol_Rpb4 PF03874.16 RLN94568.1 - 9.2e-16 58.3 3.0 3.7e-15 56.3 3.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb4 ATP12 PF07542.11 RLN94569.1 - 3.6e-35 120.8 0.3 5.2e-35 120.3 0.3 1.2 1 0 0 1 1 1 1 ATP12 chaperone protein CATSPERB PF15149.6 RLN94569.1 - 0.062 11.8 0.0 0.069 11.7 0.0 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit beta protein family US2 PF02476.15 RLN94569.1 - 0.12 13.1 0.2 0.22 12.2 0.2 1.4 1 0 0 1 1 1 0 US2 family Pkinase PF00069.25 RLN94570.1 - 1.4e-44 152.5 0.0 1.8e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN94570.1 - 5.4e-38 130.8 0.0 7e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RLN94570.1 - 0.0058 15.6 0.0 0.0081 15.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RLN94570.1 - 0.047 13.6 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN94570.1 - 0.053 12.9 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIIa PF02197.17 RLN94571.1 - 0.003 17.2 1.7 0.054 13.2 0.0 2.9 3 0 0 3 3 3 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.13 RLN94571.1 - 0.039 13.6 0.6 0.96 9.2 0.2 2.5 2 1 0 2 2 2 0 Dpy-30 motif V-SNARE_C PF12352.8 RLN94573.1 - 1.4e-05 25.2 0.4 3e-05 24.2 0.4 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Tim17 PF02466.19 RLN94573.1 - 0.00023 21.5 0.3 0.00099 19.5 0.3 2.0 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RRM_1 PF00076.22 RLN94574.1 - 2.3e-11 43.3 0.3 1.6e-07 31.1 0.1 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RLN94574.1 - 0.036 13.9 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Occluded RNA-recognition motif Duffy_binding PF05424.11 RLN94574.1 - 0.1 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Duffy binding domain AAA_6 PF12774.7 RLN94575.1 - 2.8e-136 453.8 0.0 4.3e-132 440.0 0.0 3.5 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 RLN94575.1 - 2.9e-91 305.4 0.0 5.6e-91 304.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 DHC_N2 PF08393.13 RLN94575.1 - 1.5e-89 300.9 0.5 1.5e-89 300.9 0.5 2.8 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 MT PF12777.7 RLN94575.1 - 3.1e-72 243.5 12.4 5.3e-72 242.7 12.4 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 RLN94575.1 - 2.2e-60 203.3 0.3 5.2e-56 189.0 0.0 3.9 4 0 0 4 4 4 2 P-loop containing dynein motor region Kelch_5 PF13854.6 RLN94575.1 - 7.8e-36 121.5 0.0 1.3e-05 25.0 0.0 6.7 6 0 0 6 6 6 6 Kelch motif AAA_9 PF12781.7 RLN94575.1 - 5.9e-29 100.8 0.1 3.5e-28 98.2 0.0 2.4 2 0 0 2 2 2 1 ATP-binding dynein motor region Kelch_6 PF13964.6 RLN94575.1 - 1e-28 98.6 4.4 1.3e-06 28.4 0.0 6.6 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 RLN94575.1 - 2.2e-26 91.6 7.7 1.1e-05 25.3 0.0 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain AAA_lid_1 PF17857.1 RLN94575.1 - 1.4e-23 83.0 0.4 1.4e-23 83.0 0.4 2.9 3 0 0 3 3 2 1 AAA+ lid domain AAA_5 PF07728.14 RLN94575.1 - 1.3e-21 77.1 0.3 4.4e-08 33.2 0.0 6.5 6 1 0 6 6 6 4 AAA domain (dynein-related subfamily) Kelch_3 PF13415.6 RLN94575.1 - 2.2e-21 75.6 7.0 4.8e-08 33.1 0.0 6.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 RLN94575.1 - 3.4e-20 71.4 0.0 0.00016 21.2 0.0 4.9 4 0 0 4 4 4 4 Kelch motif Dynein_AAA_lid PF17852.1 RLN94575.1 - 6.3e-19 68.3 4.7 1.9e-18 66.8 4.7 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Filamin PF00630.19 RLN94575.1 - 7.8e-15 55.6 0.0 1.8e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Filamin/ABP280 repeat Kelch_2 PF07646.15 RLN94575.1 - 3.3e-14 52.2 5.8 0.0032 17.4 0.0 6.3 6 0 0 6 6 5 3 Kelch motif AAA_16 PF13191.6 RLN94575.1 - 2.1e-07 31.5 4.7 0.27 11.6 0.0 5.9 7 0 0 7 7 5 2 AAA ATPase domain TIG PF01833.24 RLN94575.1 - 8.4e-07 29.0 1.7 4.1e-06 26.8 0.5 2.4 2 0 0 2 2 2 1 IPT/TIG domain AAA_18 PF13238.6 RLN94575.1 - 2.9e-06 27.9 4.0 4 8.0 0.0 6.2 6 0 0 6 6 5 1 AAA domain AAA_22 PF13401.6 RLN94575.1 - 5.7e-06 26.7 0.1 5 7.4 0.0 4.7 4 0 0 4 4 3 1 AAA domain AAA PF00004.29 RLN94575.1 - 2.1e-05 25.0 0.5 2.4 8.6 0.0 4.7 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 RLN94575.1 - 5.8e-05 23.5 2.2 0.047 14.0 0.1 3.9 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 RLN94575.1 - 9.6e-05 22.6 0.4 0.44 10.7 0.0 4.7 5 0 0 5 5 4 1 AAA domain Invasin_D3 PF09134.10 RLN94575.1 - 0.0003 21.1 0.0 0.00073 19.8 0.0 1.6 1 0 0 1 1 1 1 Invasin, domain 3 AAA_30 PF13604.6 RLN94575.1 - 0.0013 18.5 0.4 12 5.5 0.1 3.9 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 RLN94575.1 - 0.0054 17.0 0.1 3.1 8.0 0.0 3.6 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 RLN94575.1 - 0.006 16.9 0.5 18 5.8 0.0 3.9 4 0 0 4 4 3 0 RNA helicase T2SSE PF00437.20 RLN94575.1 - 0.014 14.5 0.9 0.49 9.4 0.0 3.1 4 0 0 4 4 4 0 Type II/IV secretion system protein AAA_11 PF13086.6 RLN94575.1 - 0.39 10.5 0.0 0.39 10.5 0.0 4.5 5 0 0 5 5 4 0 AAA domain YtkA PF13115.6 RLN94575.1 - 0.71 10.5 3.0 0.86 10.2 0.0 2.4 2 0 0 2 2 2 0 YtkA-like SRP54 PF00448.22 RLN94575.1 - 1.8 8.2 5.4 4.7 6.8 0.1 3.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain RCC1 PF00415.18 RLN94576.1 - 5.3e-74 244.7 15.6 3.3e-13 50.1 0.1 7.7 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN94576.1 - 1e-35 120.8 31.3 3e-07 30.1 0.2 8.2 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Kelch_4 PF13418.6 RLN94576.1 - 9.7e-27 92.7 16.9 1.3e-06 28.3 0.0 8.1 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_6 PF13964.6 RLN94576.1 - 1.8e-23 82.0 18.7 4.4e-07 29.9 0.2 8.8 8 1 1 9 9 9 5 Kelch motif SPRY PF00622.28 RLN94576.1 - 1.9e-23 82.9 1.3 5.8e-23 81.3 0.1 2.5 3 0 0 3 3 3 1 SPRY domain Kelch_5 PF13854.6 RLN94576.1 - 3.2e-23 81.3 19.4 3.1e-06 27.0 0.0 8.1 9 0 0 9 9 9 5 Kelch motif Kelch_1 PF01344.25 RLN94576.1 - 3.1e-17 61.9 18.7 6.3e-06 25.7 0.1 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 RLN94576.1 - 5.5e-15 55.2 10.1 0.0012 19.0 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 RLN94576.1 - 4.7e-08 32.7 21.1 0.0041 17.0 0.1 7.7 9 0 0 9 9 9 3 Kelch motif RCC1 PF00415.18 RLN94577.1 - 2.4e-71 236.1 13.8 7.3e-14 52.1 0.1 7.8 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN94577.1 - 1.6e-38 129.7 32.8 2.2e-09 36.9 0.1 9.4 10 0 0 10 10 10 6 Regulator of chromosome condensation (RCC1) repeat SPRY PF00622.28 RLN94577.1 - 2.5e-34 118.0 0.3 4.2e-14 52.7 0.0 4.9 4 0 0 4 4 4 4 SPRY domain FHA PF00498.26 RLN94577.1 - 4.8e-11 42.8 0.8 1.3e-10 41.5 0.8 1.8 1 0 0 1 1 1 1 FHA domain Vps62 PF06101.11 RLN94577.1 - 5.7e-07 28.2 0.0 1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 Yop-YscD_cpl PF16697.5 RLN94577.1 - 9.2e-07 29.1 0.0 3e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain UBA PF00627.31 RLN94577.1 - 9.7e-06 25.4 2.5 0.0061 16.4 0.0 3.8 3 0 0 3 3 3 1 UBA/TS-N domain Cupin_8 PF13621.6 RLN94578.1 - 7e-30 104.6 0.4 9.2e-30 104.2 0.4 1.2 1 0 0 1 1 1 1 Cupin-like domain RuBisCO_large_N PF02788.16 RLN94579.1 - 0.13 12.5 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain Aminotran_1_2 PF00155.21 RLN94580.1 - 1.8e-35 122.8 0.0 1.1e-20 74.2 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II YchF-GTPase_C PF06071.13 RLN94581.1 - 2.4e-64 213.5 3.1 1.7e-34 117.8 0.4 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 RLN94581.1 - 1.3e-30 105.8 0.0 4.3e-18 65.4 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN94581.1 - 5.3e-14 52.0 0.0 7.4e-06 25.6 0.0 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B MeaB PF03308.16 RLN94581.1 - 2.9e-06 26.4 0.0 0.063 12.3 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 RLN94581.1 - 5.4e-05 23.7 0.0 0.59 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 RLN94581.1 - 0.00012 21.9 0.0 1.1 8.9 0.0 3.6 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.27 RLN94581.1 - 0.00019 21.9 0.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter TGS PF02824.21 RLN94581.1 - 0.0011 18.9 0.1 0.4 10.8 0.0 2.9 2 0 0 2 2 2 1 TGS domain Dynamin_N PF00350.23 RLN94581.1 - 0.0052 16.9 0.0 7.6 6.6 0.0 3.2 2 1 1 3 3 3 1 Dynamin family PPV_E1_C PF00519.17 RLN94581.1 - 0.045 12.6 0.1 7.7 5.2 0.0 2.1 2 0 0 2 2 2 0 Papillomavirus helicase AAA_29 PF13555.6 RLN94581.1 - 0.075 12.8 0.0 20 5.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain P120R PF08062.11 RLN94581.1 - 5.7 7.4 8.0 14 6.3 1.1 2.8 2 0 0 2 2 2 0 P120R (NUC006) repeat Actin PF00022.19 RLN94582.1 - 1.2e-67 228.3 0.0 1.4e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Actin PHD PF00628.29 RLN94583.1 - 0.00024 20.9 6.2 0.0014 18.4 6.2 2.2 1 1 0 1 1 1 1 PHD-finger C1_1 PF00130.22 RLN94583.1 - 0.033 14.1 5.5 0.039 13.8 3.1 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PDZ_6 PF17820.1 RLN94584.1 - 9.9e-07 28.5 0.0 0.007 16.2 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_1 PF12812.7 RLN94584.1 - 3.5e-06 26.9 0.0 1.4e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 PDZ-like domain PDZ_2 PF13180.6 RLN94584.1 - 0.0036 17.6 0.0 0.75 10.2 0.1 2.5 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 RLN94584.1 - 0.0059 16.9 0.0 1.3 9.4 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 RLN94584.1 - 0.012 15.6 0.1 0.82 9.7 0.2 2.4 2 0 0 2 2 2 0 Tricorn protease PDZ domain Cadherin PF00028.17 RLN94585.1 - 0 1487.5 96.1 3.8e-14 52.9 0.0 67.8 69 0 0 69 69 69 62 Cadherin domain Big_9 PF17963.1 RLN94585.1 - 2.9e-57 191.4 354.1 0.00039 21.1 1.0 57.9 59 2 1 60 60 60 29 Bacterial Ig domain Cadherin_4 PF17803.1 RLN94585.1 - 4e-57 190.8 315.4 6.9e-05 23.4 0.7 57.0 56 2 2 58 58 58 24 Bacterial cadherin-like domain TIG PF01833.24 RLN94585.1 - 1.5e-30 105.1 53.7 2.2e-08 34.1 1.2 16.9 15 2 0 15 15 15 7 IPT/TIG domain Cadherin_3 PF16184.5 RLN94585.1 - 2.3e-10 40.4 54.5 3.6 7.6 0.0 25.0 30 1 0 30 30 30 2 Cadherin-like Laminin_G_3 PF13385.6 RLN94585.1 - 6.6e-10 39.3 5.4 3.7e-09 36.9 0.3 3.8 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily Cadherin_5 PF17892.1 RLN94585.1 - 0.036 14.0 43.5 0.32 11.0 0.1 14.3 17 0 0 17 17 17 0 Cadherin-like domain PKD PF00801.20 RLN94585.1 - 0.092 12.6 14.2 29 4.6 0.0 9.8 8 0 0 8 8 8 0 PKD domain BACON PF13004.7 RLN94585.1 - 0.13 12.2 4.2 5.4 7.1 1.4 5.4 2 0 0 2 2 2 0 Putative binding domain, N-terminal ChitinaseA_N PF08329.10 RLN94585.1 - 0.42 10.2 18.1 3 7.5 0.0 9.4 12 0 0 12 12 12 0 Chitinase A, N-terminal domain DDHD PF02862.17 RLN94586.1 - 7.2e-28 98.3 0.3 1.7e-27 97.1 0.0 1.6 2 0 0 2 2 2 1 DDHD domain Abhydrolase_1 PF00561.20 RLN94588.1 - 1.5e-18 67.4 0.0 6.8e-13 48.8 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN94588.1 - 2.9e-08 34.6 3.2 2.7e-07 31.4 3.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN94588.1 - 1.1e-06 28.2 0.0 0.00059 19.2 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 RLN94588.1 - 0.0019 17.9 0.0 0.0069 16.1 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Ndr PF03096.14 RLN94588.1 - 0.0046 15.7 0.0 0.0089 14.8 0.0 1.4 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.11 RLN94588.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 RLN94588.1 - 0.082 12.4 0.0 0.14 11.6 0.0 1.3 1 1 0 1 1 1 0 Prolyl oligopeptidase family HTH_38 PF13936.6 RLN94589.1 - 2.4e-08 33.6 1.2 3.5e-08 33.1 0.2 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 RLN94589.1 - 2.5e-06 27.3 0.0 4.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Tc3 transposase HTH_23 PF13384.6 RLN94589.1 - 0.059 13.2 0.1 0.059 13.2 0.1 2.7 3 1 0 3 3 3 0 Homeodomain-like domain HTH_32 PF13565.6 RLN94589.1 - 0.062 13.9 8.1 0.34 11.5 0.5 2.8 2 1 1 3 3 3 0 Homeodomain-like domain PDDEXK_1 PF12705.7 RLN94590.1 - 3.3e-25 89.5 0.0 9.2e-25 88.0 0.0 1.8 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily UvrD_C PF13361.6 RLN94590.1 - 0.0013 18.2 0.0 0.003 17.0 0.0 1.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Dna2 PF08696.11 RLN94590.1 - 0.0048 16.7 0.3 0.072 12.9 0.0 2.3 2 0 0 2 2 2 1 DNA replication factor Dna2 Csa1 PF06023.12 RLN94590.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 Cas_Cas4 PF01930.17 RLN94590.1 - 0.19 11.8 0.0 2 8.5 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function DUF83 zf-TRAF PF02176.18 RLN94591.1 - 3.4e-18 66.1 59.4 3.1e-06 27.8 4.6 6.8 6 0 0 6 6 6 5 TRAF-type zinc finger Laminin_G_3 PF13385.6 RLN94591.1 - 5.3e-10 39.6 0.0 9.4e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PAC2 PF09754.9 RLN94591.1 - 0.025 14.6 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 PAC2 family MAPEG PF01124.18 RLN94593.1 - 2.3e-17 63.1 0.3 2.9e-17 62.8 0.3 1.1 1 0 0 1 1 1 1 MAPEG family HofP PF10748.9 RLN94593.1 - 0.08 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 DNA utilization proteins HofP MAPEG PF01124.18 RLN94594.1 - 3.2e-15 56.2 0.5 4.5e-15 55.7 0.5 1.2 1 0 0 1 1 1 1 MAPEG family FA_desaturase PF00487.24 RLN94595.1 - 7.5e-33 114.4 17.2 5.1e-32 111.7 13.8 2.6 2 1 1 3 3 3 1 Fatty acid desaturase Cyt-b5 PF00173.28 RLN94595.1 - 9.3e-23 80.2 0.3 2.7e-20 72.3 0.0 3.3 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain Jiv90 PF14901.6 RLN94595.1 - 0.024 14.8 0.1 0.074 13.2 0.1 1.8 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone BTB PF00651.31 RLN94596.1 - 3.1e-20 72.5 0.0 5.5e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 RLN94596.1 - 4.2e-13 49.3 0.1 6.7e-13 48.6 0.1 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch DNA_pol_phi PF04931.13 RLN94596.1 - 0.13 10.4 3.3 0.17 9.9 3.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 RLN94596.1 - 2.3 7.4 6.9 3.7 6.8 6.9 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 RLN94596.1 - 4.1 7.4 8.2 1.3 9.0 5.1 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF4637 PF15470.6 RLN94596.1 - 4.5 7.0 7.2 0.21 11.3 1.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) RabGAP-TBC PF00566.18 RLN94597.1 - 5e-13 49.2 5.2 4e-08 33.2 2.9 3.0 1 1 0 2 2 2 2 Rab-GTPase-TBC domain GST_C_3 PF14497.6 RLN94597.1 - 0.036 14.3 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DFRP_C PF16543.5 RLN94598.1 - 4.7e-07 30.2 10.9 4.7e-07 30.2 10.9 2.4 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 NOA36 PF06524.12 RLN94598.1 - 0.034 13.5 13.4 0.04 13.2 13.4 1.2 1 0 0 1 1 1 0 NOA36 protein Paf1 PF03985.13 RLN94598.1 - 0.95 8.4 15.8 1.1 8.1 15.8 1.0 1 0 0 1 1 1 0 Paf1 NPR3 PF03666.13 RLN94598.1 - 1.2 7.9 5.9 0.98 8.1 5.1 1.2 1 1 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SURF2 PF05477.11 RLN94598.1 - 1.8 8.2 14.8 1.9 8.1 14.8 1.0 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Nop14 PF04147.12 RLN94598.1 - 3 5.9 22.2 3.5 5.7 22.2 1.0 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 RLN94598.1 - 7.5 6.1 13.8 10 5.6 13.8 1.2 1 0 0 1 1 1 0 PPP4R2 DDE_1 PF03184.19 RLN94600.1 - 6.1e-25 87.9 0.0 1e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN94600.1 - 5.6e-10 39.1 0.0 1.3e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain PH PF00169.29 RLN94601.1 - 5.2e-06 26.9 0.0 1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 PH domain Na_H_Exchanger PF00999.21 RLN94602.1 - 1.6e-43 148.9 35.0 1.4e-41 142.6 17.8 3.0 2 1 1 3 3 3 3 Sodium/hydrogen exchanger family IBN_N PF03810.19 RLN94603.1 - 0.017 15.0 0.5 0.081 12.9 0.5 2.2 1 0 0 1 1 1 0 Importin-beta N-terminal domain Phage_int_SAM_4 PF13495.6 RLN94604.1 - 0.0017 18.8 0.2 0.0047 17.4 0.2 1.8 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 RLN94604.1 - 0.016 15.5 0.2 0.045 14.1 0.1 1.8 2 1 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Rhomboid PF01694.22 RLN94605.1 - 8e-26 90.8 9.7 1.4e-25 90.0 9.7 1.3 1 0 0 1 1 1 1 Rhomboid family Phage_GP20 PF06810.11 RLN94606.1 - 0.0001 22.1 1.6 0.00013 21.8 1.6 1.1 1 0 0 1 1 1 1 Phage minor structural protein GP20 DUF4472 PF14739.6 RLN94606.1 - 0.028 15.2 1.5 0.036 14.8 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) NCA2 PF08637.10 RLN94606.1 - 0.029 13.5 0.3 0.035 13.3 0.3 1.1 1 0 0 1 1 1 0 ATP synthase regulation protein NCA2 DUF4602 PF15375.6 RLN94606.1 - 0.084 13.2 2.7 0.11 12.8 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) LPP PF04728.13 RLN94606.1 - 0.21 12.0 4.6 0.91 10.0 4.6 2.1 1 1 0 1 1 1 0 Lipoprotein leucine-zipper Clat_adaptor_s PF01217.20 RLN94607.1 - 5e-39 133.5 4.3 1e-33 116.2 2.2 2.8 2 1 0 2 2 2 2 Clathrin adaptor complex small chain CENP-B_dimeris PF09026.10 RLN94609.1 - 0.022 15.2 13.3 0.027 14.8 13.3 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 RLN94609.1 - 0.19 9.9 5.9 0.18 10.0 5.9 1.0 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 RLN94609.1 - 0.3 10.7 2.5 0.3 10.8 2.5 1.2 1 0 0 1 1 1 0 FAM176 family BUD22 PF09073.10 RLN94609.1 - 0.37 10.1 12.1 0.39 10.0 12.1 1.0 1 0 0 1 1 1 0 BUD22 TRAP_alpha PF03896.16 RLN94609.1 - 1.7 7.8 4.2 1.7 7.8 4.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 RLN94609.1 - 2.1 7.6 9.9 2.4 7.4 9.9 1.1 1 0 0 1 1 1 0 NOA36 protein Astro_capsid_p PF12226.8 RLN94609.1 - 2.5 7.2 9.8 2.9 7.0 9.8 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein EBV-NA3 PF05009.12 RLN94609.1 - 2.5 7.5 5.3 2.8 7.4 5.3 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) YL1 PF05764.13 RLN94609.1 - 3.8 7.5 12.0 4.4 7.4 12.0 1.0 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 RLN94609.1 - 4.1 5.6 7.8 4.1 5.6 7.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 RLN94609.1 - 6.5 4.7 12.2 7.2 4.6 12.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi Hydrolase PF00702.26 RLN94610.1 - 1.8e-18 67.6 0.3 2.6e-18 67.1 0.3 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 RLN94610.1 - 1.4e-05 25.0 0.6 0.00029 20.6 0.5 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 RLN94610.1 - 5.9e-05 23.4 0.4 0.00017 22.0 0.4 1.9 1 0 0 1 1 1 1 Heavy-metal-associated domain Tam41_Mmp37 PF09139.11 RLN94610.1 - 0.093 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial HAD PF12710.7 RLN94610.1 - 0.15 12.4 0.0 0.34 11.3 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Sedlin_N PF04628.13 RLN94612.1 - 2.1e-40 137.9 0.0 2.3e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 RLN94612.1 - 5.4e-14 52.3 0.0 7e-13 48.7 0.0 2.0 2 0 0 2 2 2 1 Sybindin-like family Ribosomal_S19e PF01090.19 RLN94613.1 - 1.5e-57 193.2 0.3 1.6e-57 193.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_12 PF08461.10 RLN94613.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Sin_N PF04801.13 RLN94615.1 - 2.1e-52 178.8 11.6 1.1e-47 163.3 10.1 2.9 1 1 1 2 2 2 2 Sin-like protein conserved region FYVE PF01363.21 RLN94617.1 - 0.0037 17.4 6.5 0.0073 16.4 6.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger zf-B_box PF00643.24 RLN94617.1 - 4.6 7.5 8.9 0.43 10.8 3.5 2.0 1 1 1 2 2 2 0 B-box zinc finger BBIP10 PF14777.6 RLN94618.1 - 1e-18 66.6 1.7 6.2e-18 64.1 0.4 3.0 2 0 0 2 2 2 1 Cilia BBSome complex subunit 10 NUC153 PF08159.12 RLN94618.1 - 1.9e-08 34.0 2.0 5.8e-07 29.2 0.1 3.5 3 0 0 3 3 3 1 NUC153 domain TFIIB PF00382.19 RLN94619.1 - 0.063 13.3 1.6 1.1 9.4 0.0 2.7 2 1 0 2 2 2 0 Transcription factor TFIIB repeat DUF3824 PF12868.7 RLN94619.1 - 0.089 13.5 6.6 0.08 13.6 5.4 1.6 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF908 PF06012.12 RLN94619.1 - 3.7 6.9 7.4 5.3 6.4 7.5 1.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF908) MAJIN PF15077.6 RLN94619.1 - 8 6.2 8.3 5.8 6.6 6.3 1.8 2 0 0 2 2 2 0 Membrane-anchored junction protein WEMBL PF05701.11 RLN94620.1 - 3.9e-07 29.2 7.0 3.9e-07 29.2 7.0 1.7 2 0 0 2 2 2 1 Weak chloroplast movement under blue light Golgin_A5 PF09787.9 RLN94620.1 - 0.00034 20.2 24.7 0.017 14.6 0.4 3.8 3 1 1 4 4 4 2 Golgin subfamily A member 5 GRIP PF01465.20 RLN94620.1 - 0.00046 20.0 0.1 0.0013 18.6 0.1 1.7 1 0 0 1 1 1 1 GRIP domain DUF4085 PF13315.6 RLN94620.1 - 0.0044 16.7 1.4 0.021 14.5 0.0 2.2 1 1 0 2 2 2 1 Protein of unknown function (DUF4085) Baculo_LEF-10 PF07206.11 RLN94620.1 - 0.28 11.4 1.0 8.4 6.6 0.1 2.5 2 0 0 2 2 2 0 Baculovirus late expression factor 10 (LEF-10) DUF2951 PF11166.8 RLN94620.1 - 4.1 7.7 9.4 3.4 8.0 1.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) UPF0242 PF06785.11 RLN94620.1 - 6.8 6.7 22.7 8.1 6.5 5.2 2.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus RILP PF11461.8 RLN94620.1 - 9.8 6.5 12.4 0.33 11.2 2.6 3.4 4 0 0 4 4 4 0 Rab interacting lysosomal protein Thioredoxin_8 PF13905.6 RLN94622.1 - 1.5e-25 89.3 0.0 1.9e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 RLN94622.1 - 9e-08 32.5 0.0 1.2e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 RLN94622.1 - 6e-07 29.4 0.1 0.00026 20.9 0.2 2.2 1 1 1 2 2 2 2 Thioredoxin Redoxin PF08534.10 RLN94622.1 - 0.00018 21.2 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 RLN94622.1 - 0.00065 19.6 0.0 0.00077 19.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 RLN94622.1 - 0.0042 16.9 0.0 0.045 13.5 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin Methyltransf_3 PF01596.17 RLN94622.1 - 0.069 12.3 0.2 0.1 11.8 0.2 1.2 1 0 0 1 1 1 0 O-methyltransferase Thioredoxin_7 PF13899.6 RLN94622.1 - 0.16 12.2 0.9 4.2 7.6 0.9 2.6 1 1 0 1 1 1 0 Thioredoxin-like Glyco_tran_28_C PF04101.16 RLN94623.1 - 0.038 14.0 1.0 0.067 13.2 0.1 1.8 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain APG6_N PF17675.1 RLN94623.1 - 6.7 7.3 12.9 17 6.0 9.4 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region TPX2_importin PF12214.8 RLN94624.1 - 0.0061 16.8 1.2 0.084 13.1 0.1 2.4 1 1 1 2 2 2 2 Cell cycle regulated microtubule associated protein FYVE PF01363.21 RLN94625.1 - 2e-09 37.4 9.9 7.6e-09 35.6 9.9 2.0 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN94625.1 - 0.00085 19.5 3.7 0.0019 18.4 3.7 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger zf-RING_5 PF14634.6 RLN94625.1 - 0.4 10.7 9.0 1 9.4 9.0 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 RLN94625.1 - 0.59 10.5 8.2 1.5 9.2 8.2 1.8 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 RLN94625.1 - 0.6 10.2 6.5 1.5 8.9 6.5 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-B_box PF00643.24 RLN94625.1 - 0.78 9.9 5.3 2.2 8.5 5.3 1.8 1 0 0 1 1 1 0 B-box zinc finger Prok-RING_4 PF14447.6 RLN94625.1 - 0.94 9.4 10.2 0.35 10.8 6.2 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 RLN94625.1 - 6.7 6.7 7.0 33 4.5 7.4 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) EF-hand_1 PF00036.32 RLN94626.1 - 9.6e-32 106.2 13.2 1.1e-08 34.0 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RLN94626.1 - 8.3e-30 103.1 6.9 4.2e-16 59.2 0.6 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RLN94626.1 - 1.8e-27 94.9 5.2 4.1e-14 52.2 0.3 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RLN94626.1 - 1.1e-24 84.2 9.8 3.4e-06 26.6 0.2 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RLN94626.1 - 6.2e-23 79.2 11.2 4.2e-06 26.0 0.1 4.4 4 0 0 4 4 4 4 EF hand Pkinase PF00069.25 RLN94626.1 - 3e-13 49.8 0.0 2.6e-07 30.3 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain SPARC_Ca_bdg PF10591.9 RLN94626.1 - 7.5e-09 35.9 0.1 0.00033 21.0 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 RLN94626.1 - 2e-08 34.4 2.1 0.0031 17.8 0.0 3.1 4 0 0 4 4 2 2 EF-hand domain EF-hand_4 PF12763.7 RLN94626.1 - 3.5e-08 33.3 4.4 0.00086 19.2 0.1 3.2 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 RLN94626.1 - 3e-07 30.5 0.1 0.014 15.3 0.0 2.4 2 0 0 2 2 2 2 Tellurite resistance protein TerB Pkinase_Tyr PF07714.17 RLN94626.1 - 0.0013 18.1 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Dockerin_1 PF00404.18 RLN94626.1 - 0.0013 18.8 0.2 0.95 9.7 0.1 2.8 2 1 0 2 2 2 1 Dockerin type I domain DUF3349 PF11829.8 RLN94626.1 - 0.011 16.5 0.0 1.7 9.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) Mu-like_Pro PF10123.9 RLN94626.1 - 0.074 12.6 0.5 0.86 9.1 0.0 2.3 2 1 0 2 2 2 0 Mu-like prophage I protein UPF0154 PF03672.13 RLN94626.1 - 0.14 12.2 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) PepSY_2 PF13670.6 RLN94626.1 - 0.16 12.0 2.8 12 6.0 0.0 2.5 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain PDZ_6 PF17820.1 RLN94627.1 - 9.1e-13 47.9 0.0 9.1e-13 47.9 0.0 1.7 2 0 0 2 2 2 1 PDZ domain ZZ PF00569.17 RLN94627.1 - 4.5e-10 39.2 3.3 8.1e-10 38.4 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type PDZ PF00595.24 RLN94627.1 - 1.4e-06 28.6 0.0 6.6e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 RLN94627.1 - 9.6e-05 22.6 0.7 0.00017 21.8 0.1 1.8 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 RLN94627.1 - 0.0032 17.4 0.0 0.0082 16.1 0.0 1.6 1 0 0 1 1 1 1 Tricorn protease PDZ domain GRASP55_65 PF04495.14 RLN94627.1 - 0.023 15.0 0.0 0.044 14.1 0.0 1.4 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain SDA1 PF05285.12 RLN94627.1 - 0.23 10.8 4.8 0.38 10.1 4.8 1.3 1 0 0 1 1 1 0 SDA1 Barttin PF15462.6 RLN94627.1 - 0.3 10.8 4.9 0.79 9.5 4.9 1.7 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Ribosomal_L22 PF00237.19 RLN94628.1 - 5.4e-19 68.3 0.1 8.5e-19 67.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e HSP70 PF00012.20 RLN94629.1 - 2e-07 29.6 2.4 2.2e-07 29.5 2.4 1.0 1 0 0 1 1 1 1 Hsp70 protein DDE_3 PF13358.6 RLN94632.1 - 1.8e-06 27.8 0.0 3.8e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_5 PF01022.20 RLN94632.1 - 5.9e-06 26.1 0.0 8.8e-05 22.3 0.0 2.5 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 RLN94632.1 - 1.3e-05 24.6 0.6 8.6e-05 22.0 0.2 2.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding LacI PF00356.21 RLN94632.1 - 0.00011 21.9 0.1 0.00045 19.9 0.4 2.0 2 0 0 2 2 1 1 Bacterial regulatory proteins, lacI family HTH_38 PF13936.6 RLN94632.1 - 0.00015 21.5 0.2 0.00056 19.6 0.2 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 RLN94632.1 - 0.00018 21.3 0.7 0.00043 20.1 0.7 1.6 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 RLN94632.1 - 0.0012 18.7 0.2 0.004 17.1 0.2 1.8 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 RLN94632.1 - 0.0018 18.1 0.0 0.005 16.7 0.0 1.8 1 0 0 1 1 1 1 MarR family HTH_10 PF04967.12 RLN94632.1 - 0.0019 17.9 0.3 0.013 15.3 0.1 2.6 3 0 0 3 3 3 1 HTH DNA binding domain HTH_3 PF01381.22 RLN94632.1 - 0.0036 17.3 0.5 0.012 15.6 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix HTH_Tnp_Tc3_2 PF01498.18 RLN94632.1 - 0.0062 16.8 0.6 0.56 10.5 0.5 2.6 2 0 0 2 2 2 1 Transposase Phage_CI_repr PF07022.13 RLN94632.1 - 0.0062 16.6 0.0 0.016 15.3 0.0 1.8 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_AsnC-type PF13404.6 RLN94632.1 - 0.0065 16.3 0.8 0.023 14.5 0.6 2.1 1 1 1 2 2 2 1 AsnC-type helix-turn-helix domain HTH_20 PF12840.7 RLN94632.1 - 0.023 14.8 0.1 0.25 11.4 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_1 PF00126.27 RLN94632.1 - 0.025 14.5 1.0 0.069 13.1 1.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Sigma70_r4 PF04545.16 RLN94632.1 - 0.031 13.8 0.3 0.085 12.4 0.3 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_36 PF13730.6 RLN94632.1 - 0.048 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 RLN94632.1 - 0.054 13.5 1.2 0.13 12.3 0.7 2.0 2 0 0 2 2 2 0 Winged helix-turn helix HTH_IclR PF09339.10 RLN94632.1 - 0.058 13.2 0.4 0.16 11.8 0.4 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_Tnp_4 PF13613.6 RLN94632.1 - 0.06 13.1 0.3 0.19 11.5 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease HTH_28 PF13518.6 RLN94632.1 - 0.089 12.9 0.3 0.22 11.7 0.3 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 RLN94632.1 - 0.09 12.6 0.2 0.24 11.2 0.2 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_50 PF18024.1 RLN94632.1 - 0.1 12.2 0.2 0.29 10.8 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain MerR PF00376.23 RLN94632.1 - 0.21 11.4 1.8 7.3 6.5 0.2 3.1 3 0 0 3 3 3 0 MerR family regulatory protein HTH_31 PF13560.6 RLN94632.1 - 0.62 10.5 13.1 1.4 9.3 10.7 2.9 2 1 0 2 2 2 0 Helix-turn-helix domain VPS13_C PF16909.5 RLN94634.1 - 7.6e-42 143.1 0.4 1.5e-40 138.9 0.0 2.4 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 RLN94634.1 - 8.2e-36 123.8 0.0 7.5e-31 107.5 0.0 3.2 3 0 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 Apt1 PF10351.9 RLN94634.1 - 0.016 14.1 0.0 0.029 13.3 0.0 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain ATG_C PF09333.11 RLN94634.1 - 0.036 14.4 0.0 0.17 12.3 0.0 2.1 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain ABC_tran PF00005.27 RLN94635.1 - 1.5e-32 113.0 0.0 2.7e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 RLN94635.1 - 5e-22 78.9 8.5 8.6e-22 78.1 8.5 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region mTERF PF02536.14 RLN94635.1 - 2.7e-10 39.7 0.0 4.7e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 mTERF SMC_N PF02463.19 RLN94635.1 - 9.2e-09 35.0 0.0 1.2e-07 31.4 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain PBP1_TM PF14812.6 RLN94635.1 - 0.00013 22.3 0.6 0.00013 22.3 0.6 1.9 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_22 PF13401.6 RLN94635.1 - 0.0038 17.5 0.4 0.023 15.0 0.4 2.1 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 RLN94635.1 - 0.0077 16.0 0.1 0.022 14.5 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.6 RLN94635.1 - 0.026 14.9 0.2 0.075 13.4 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.25 RLN94635.1 - 0.051 13.2 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RsgA_GTPase PF03193.16 RLN94635.1 - 0.055 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase DUF3243 PF11588.8 RLN94635.1 - 0.059 13.7 0.0 0.23 11.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) AAA_25 PF13481.6 RLN94635.1 - 0.096 12.2 0.5 0.56 9.8 0.1 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 RLN94635.1 - 0.12 12.4 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cnd2 PF05786.14 RLN94635.1 - 0.12 11.0 0.1 0.19 10.4 0.1 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 AAA_23 PF13476.6 RLN94635.1 - 0.17 12.4 0.4 0.38 11.2 0.4 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 RLN94635.1 - 0.24 11.7 0.6 4.2 7.7 0.1 2.8 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 RLN94635.1 - 0.24 11.1 2.1 0.68 9.6 0.7 2.5 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 RLN94635.1 - 0.24 11.2 0.6 0.55 10.0 0.6 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain HLH PF00010.26 RLN94636.1 - 0.061 13.3 5.1 0.15 12.0 5.1 1.7 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain FAM76 PF16046.5 RLN94636.1 - 0.077 12.3 2.6 0.11 11.9 2.6 1.1 1 0 0 1 1 1 0 FAM76 protein TSC22 PF01166.18 RLN94636.1 - 0.17 12.2 2.9 2 8.8 0.1 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family bZIP_2 PF07716.15 RLN94637.1 - 0.23 11.6 2.9 0.49 10.5 2.9 1.5 1 0 0 1 1 1 0 Basic region leucine zipper CDC27 PF09507.10 RLN94638.1 - 0.38 10.1 26.9 0.49 9.7 26.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 VSG_B PF13206.6 RLN94638.1 - 0.9 8.7 16.8 1.3 8.2 16.8 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain HSP70 PF00012.20 RLN94638.1 - 2.3 6.3 12.8 2.7 6.0 12.8 1.1 1 0 0 1 1 1 0 Hsp70 protein Atg14 PF10186.9 RLN94638.1 - 2.4 7.2 14.2 3.4 6.7 14.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 RLN94638.1 - 3.5 6.4 14.9 5 5.9 14.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Asp-B-Hydro_N PF05279.11 RLN94638.1 - 3.6 7.6 16.5 5.5 7.0 16.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Mitofilin PF09731.9 RLN94638.1 - 5.9 5.6 26.6 7.9 5.2 26.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein GAF PF01590.26 RLN94644.1 - 5.1e-35 121.0 0.0 3.5e-17 63.3 0.0 2.2 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 RLN94644.1 - 4.7e-21 75.5 0.0 7.1e-13 49.0 0.0 2.2 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 RLN94644.1 - 2.3e-13 50.6 0.0 5.9e-06 26.7 0.0 2.5 2 1 0 2 2 2 2 GAF domain dCache_1 PF02743.18 RLN94644.1 - 0.0014 18.4 0.2 0.12 12.1 0.1 2.3 2 1 0 2 2 2 1 Cache domain DUF2853 PF11015.8 RLN94644.1 - 0.019 15.6 0.1 0.18 12.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2853) Sigma54_CBD PF04963.13 RLN94644.1 - 0.059 13.2 0.0 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 factor, core binding domain DUF2111 PF09884.9 RLN94644.1 - 0.13 12.3 0.0 27 4.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2111) WW PF00397.26 RLN94645.1 - 5.5e-09 35.9 1.4 1.2e-08 34.8 1.4 1.6 1 0 0 1 1 1 1 WW domain DUF2155 PF09923.9 RLN94645.1 - 0.4 10.9 3.5 1.5 9.1 0.2 3.3 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2155) Adap_comp_sub PF00928.21 RLN94646.1 - 3.7e-13 49.5 0.0 1e-12 48.0 0.0 1.7 2 0 0 2 2 2 1 Adaptor complexes medium subunit family CorA PF01544.18 RLN94646.1 - 0.00079 18.8 10.0 0.0037 16.6 10.0 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2569 PF10754.9 RLN94646.1 - 0.018 15.5 2.6 0.034 14.6 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) CorA PF01544.18 RLN94647.1 - 3.3e-07 29.9 8.9 1.2e-06 28.0 8.9 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2569 PF10754.9 RLN94647.1 - 0.027 14.9 1.2 0.046 14.2 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) TssO PF17561.2 RLN94647.1 - 0.24 11.5 1.0 27 4.8 0.6 2.4 2 0 0 2 2 2 0 Type VI secretion system, TssO mit_SMPDase PF14724.6 RLN94648.1 - 3.9e-20 71.5 0.0 1.5e-19 69.5 0.0 1.9 1 1 0 1 1 1 1 Mitochondrial-associated sphingomyelin phosphodiesterase Bromodomain PF00439.25 RLN94649.1 - 7e-14 51.7 0.0 1.6e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 RLN94649.1 - 0.017 15.0 1.1 0.035 14.0 1.1 1.5 1 0 0 1 1 1 0 PHD-finger ADSL_C PF10397.9 RLN94650.1 - 5.3e-19 68.5 0.1 3.1e-18 66.1 0.0 2.3 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Lyase_1 PF00206.20 RLN94650.1 - 8.9e-16 58.2 0.3 2.4e-11 43.6 0.2 2.3 1 1 0 2 2 2 2 Lyase TPR_1 PF00515.28 RLN94651.1 - 4.3e-17 61.1 1.4 1.3e-05 24.8 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 RLN94651.1 - 2.9e-16 58.2 11.4 0.00014 21.7 0.1 5.3 6 0 0 6 6 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 RLN94651.1 - 4.3e-15 55.1 2.8 2.5e-05 23.8 0.0 5.5 2 2 3 5 5 5 4 TPR repeat TPR_16 PF13432.6 RLN94651.1 - 2.1e-14 53.9 7.0 0.00044 20.8 0.2 3.8 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 RLN94651.1 - 1e-10 41.2 0.8 0.00019 21.6 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN94651.1 - 4.1e-10 39.8 10.5 7e-06 26.2 0.9 3.9 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 RLN94651.1 - 4.8e-10 39.8 3.1 0.0003 21.2 0.2 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat Glyco_transf_41 PF13844.6 RLN94651.1 - 2.6e-09 36.1 0.0 3.7e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 41 ANAPC3 PF12895.7 RLN94651.1 - 1.5e-08 34.7 1.0 4.1e-06 26.9 0.2 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 RLN94651.1 - 2.6e-06 27.2 1.5 0.48 10.8 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN94651.1 - 4.2e-06 26.4 4.0 0.64 10.2 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN94651.1 - 8.9e-06 25.8 15.8 0.0071 16.5 0.2 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN94651.1 - 1e-05 26.0 17.2 0.67 10.9 0.1 6.4 3 2 4 7 7 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 RLN94651.1 - 5.1e-05 23.0 12.4 0.55 10.2 0.0 5.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 RLN94651.1 - 0.00011 22.4 5.5 0.0065 16.8 0.4 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 RLN94651.1 - 0.00031 20.0 3.6 0.00078 18.7 1.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 RLN94651.1 - 0.0015 19.0 6.0 0.0076 16.7 0.7 3.3 1 1 0 2 2 2 1 Bacterial transcriptional activator domain TPR_6 PF13174.6 RLN94651.1 - 0.0051 17.4 13.3 3.3 8.5 0.0 6.4 8 0 0 8 8 5 1 Tetratricopeptide repeat Glyco_trans_1_4 PF13692.6 RLN94651.1 - 0.0072 16.8 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 TPR_4 PF07721.14 RLN94651.1 - 0.022 15.3 8.7 10 7.1 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 RLN94651.1 - 0.049 13.3 0.2 4.8 6.8 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain MIT PF04212.18 RLN94651.1 - 0.058 13.5 0.2 16 5.7 0.0 4.0 2 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain BRCA-2_OB1 PF09103.10 RLN94651.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 SHNi-TPR PF10516.9 RLN94651.1 - 0.18 11.3 1.0 83 2.8 0.2 3.6 3 0 0 3 3 3 0 SHNi-TPR SesA PF17107.5 RLN94652.1 - 1.3 9.2 5.4 26 5.0 0.7 3.2 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF1018 PF06252.12 RLN94653.1 - 0.085 13.8 3.9 0.46 11.5 3.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) SlyX PF04102.12 RLN94653.1 - 0.43 11.2 2.2 0.6 10.8 0.5 2.2 2 0 0 2 2 2 0 SlyX DUF3381 PF11861.8 RLN94653.1 - 7.4 6.4 8.4 0.45 10.3 2.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3381) FmdE PF02663.14 RLN94654.1 - 0.03 14.3 0.3 0.077 13.0 0.3 1.7 1 1 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon SlyX PF04102.12 RLN94654.1 - 0.096 13.3 1.1 0.23 12.1 0.2 2.1 2 0 0 2 2 2 0 SlyX DcrB PF08786.11 RLN94656.1 - 0.12 12.4 1.7 0.25 11.4 1.7 1.5 1 0 0 1 1 1 0 DcrB DUF4515 PF14988.6 RLN94660.1 - 0.0038 17.1 2.2 0.0061 16.4 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4515) SPICE PF15678.5 RLN94660.1 - 0.0072 15.7 0.0 0.01 15.2 0.0 1.1 1 0 0 1 1 1 1 Centriole duplication and mitotic chromosome congression SH3_9 PF14604.6 RLN94660.1 - 0.0076 16.1 0.0 0.22 11.4 0.0 2.6 2 0 0 2 2 2 1 Variant SH3 domain PHM7_cyt PF14703.6 RLN94660.1 - 0.011 16.0 0.2 6.5 7.0 0.0 2.5 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter HR1 PF02185.16 RLN94660.1 - 0.047 13.8 3.9 2.1 8.5 0.3 2.6 2 0 0 2 2 2 0 Hr1 repeat Lzipper-MIP1 PF14389.6 RLN94660.1 - 0.42 11.0 4.6 1.4 9.2 1.2 2.3 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 TSC22 PF01166.18 RLN94660.1 - 0.82 10.0 5.0 1.4 9.2 0.6 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family LapA_dom PF06305.11 RLN94660.1 - 8.4 6.3 6.1 18 5.2 0.2 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF3391 PF11871.8 RLN94661.1 - 0.054 14.0 0.7 0.11 13.0 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) DHR10 PF18595.1 RLN94661.1 - 4.4 7.4 9.8 1.5 8.9 1.1 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF4136 PF13590.6 RLN94662.1 - 0.12 13.0 0.4 0.19 12.3 0.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4136) Meiotic_rec114 PF03525.14 RLN94662.1 - 0.16 10.9 2.7 2.1 7.3 0.7 2.2 1 1 1 2 2 2 0 Meiotic recombination protein rec114 NYD-SP28_assoc PF14775.6 RLN94662.1 - 2.6 8.2 6.5 1.6 8.8 1.7 2.6 2 1 0 2 2 2 0 Sperm tail C-terminal domain MATalpha_HMGbox PF04769.12 RLN94665.1 - 0.036 13.4 0.1 0.061 12.6 0.1 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Tup_N PF08581.10 RLN94666.1 - 0.15 12.4 1.4 4.1 7.8 0.1 2.8 3 0 0 3 3 3 0 Tup N-terminal GDH_N PF12466.8 RLN94667.1 - 0.07 13.3 0.2 0.24 11.7 0.2 1.9 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal Nup54 PF13874.6 RLN94667.1 - 0.15 12.1 3.7 1.2 9.3 3.7 2.2 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Arm PF00514.23 RLN94669.1 - 2.6e-27 94.0 19.6 0.00011 22.1 0.1 8.6 9 0 0 9 9 9 7 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 RLN94669.1 - 1.7e-06 27.7 0.1 0.0026 17.3 0.0 3.3 1 1 2 3 3 3 1 Armadillo-like HEAT_EZ PF13513.6 RLN94669.1 - 2e-05 24.9 25.2 0.0038 17.7 1.1 6.8 4 3 2 6 6 6 3 HEAT-like repeat Atx10homo_assoc PF09759.9 RLN94669.1 - 3.2e-05 23.9 4.7 5.3 7.1 0.1 5.0 2 2 4 6 6 6 3 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 RLN94669.1 - 0.00045 20.6 22.2 0.066 13.6 1.8 5.1 1 1 7 8 8 8 6 HEAT repeats HEAT PF02985.22 RLN94669.1 - 0.0011 19.0 10.1 34 5.1 0.0 7.6 8 0 0 8 8 8 0 HEAT repeat UNC45-central PF11701.8 RLN94669.1 - 0.0019 18.2 3.6 1.1 9.2 0.1 4.1 3 1 2 5 5 5 2 Myosin-binding striated muscle assembly central Prok-E2_C PF14459.6 RLN94669.1 - 0.009 16.2 6.4 0.61 10.3 0.0 4.5 1 1 3 5 5 5 1 Prokaryotic E2 family C Spermine_synth PF01564.17 RLN94671.1 - 0.024 14.0 0.0 0.039 13.4 0.0 1.4 2 0 0 2 2 2 0 Spermine/spermidine synthase domain Exo_endo_phos PF03372.23 RLN94672.1 - 1e-07 31.7 0.1 4.2e-06 26.5 0.1 2.3 1 1 1 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Dymeclin PF09742.9 RLN94673.1 - 9.6e-116 387.7 1.5 6.2e-115 385.0 1.5 1.9 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF4473 PF14747.6 RLN94673.1 - 0.098 13.2 0.5 0.28 11.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) Ribosomal_L32e PF01655.18 RLN94674.1 - 3.4e-51 172.2 1.6 4.2e-51 171.9 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 CDH1_2_SANT_HL1 PF18375.1 RLN94675.1 - 0.2 12.4 0.0 0.35 11.6 0.0 1.3 1 0 0 1 1 1 0 CDH1/2 SANT-Helical linker 1 Aa_trans PF01490.18 RLN94676.1 - 3.3e-47 161.1 6.3 6.1e-47 160.2 6.3 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein MscS_TM PF12794.7 RLN94676.1 - 2.3 7.0 12.5 0.31 9.8 0.1 3.2 3 0 0 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 UCH PF00443.29 RLN94677.1 - 7.6e-42 143.6 0.0 1.7e-41 142.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN94677.1 - 1e-18 68.0 0.1 6.4e-18 65.4 0.1 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Aa_trans PF01490.18 RLN94679.1 - 1e-30 106.8 12.6 1.5e-30 106.3 12.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3784 PF12650.7 RLN94679.1 - 2 8.6 14.6 1.1 9.5 0.1 4.1 3 2 1 4 4 4 0 Domain of unknown function (DUF3784) Aa_trans PF01490.18 RLN94680.1 - 1.6e-44 152.2 16.3 2.3e-44 151.8 16.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DDE_1 PF03184.19 RLN94681.1 - 4.7e-14 52.4 0.0 1.2e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN94681.1 - 2.5e-06 27.4 0.1 7.4e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 RLN94681.1 - 6.2e-06 26.0 0.0 0.0012 18.7 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HAD_2 PF13419.6 RLN94682.1 - 1.6e-13 51.1 0.0 2.3e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RLN94682.1 - 1.5e-10 41.7 0.0 1.8e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RLN94682.1 - 0.0018 18.3 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like RNA_pol_Rpb6 PF01192.22 RLN94682.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb6 Pkinase PF00069.25 RLN94683.1 - 6.7e-22 78.1 0.0 2.8e-12 46.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN94683.1 - 9.1e-13 48.1 0.0 3.2e-07 29.9 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase SAP PF02037.27 RLN94683.1 - 9.9e-07 28.4 0.3 2.6e-06 27.0 0.1 1.8 2 0 0 2 2 2 1 SAP domain PINIT PF14324.6 RLN94683.1 - 0.00066 20.0 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 PINIT domain Ribonuclease_P PF00825.18 RLN94686.1 - 0.36 10.9 2.3 0.55 10.3 0.1 2.4 3 0 0 3 3 3 0 Ribonuclease P T_cell_tran_alt PF15128.6 RLN94687.1 - 0.012 15.4 0.1 0.024 14.5 0.0 1.6 1 1 1 2 2 2 0 T-cell leukemia translocation-altered EPV_E5 PF08135.11 RLN94687.1 - 0.013 15.9 0.8 0.02 15.3 0.8 1.3 1 0 0 1 1 1 0 Major transforming protein E5 family Ank_5 PF13857.6 RLN94688.1 - 3.4e-34 116.4 5.9 1.2e-10 41.5 0.7 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN94688.1 - 2.7e-31 108.0 1.3 7.8e-12 45.6 0.9 3.3 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN94688.1 - 1.1e-30 105.5 0.9 1e-10 41.9 0.1 4.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN94688.1 - 1.3e-25 86.6 4.2 0.00026 21.2 0.0 5.9 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 RLN94688.1 - 1.1e-21 76.3 10.6 1.7e-05 25.0 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat FAD-oxidase_C PF02913.19 RLN94689.1 - 3.2e-55 187.5 0.1 5.7e-55 186.6 0.1 1.4 1 1 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 RLN94689.1 - 9e-39 132.4 1.2 1.7e-38 131.5 1.2 1.5 1 0 0 1 1 1 1 FAD binding domain SNF2_N PF00176.23 RLN94692.1 - 1e-71 241.5 0.3 2.5e-71 240.2 0.3 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 RLN94692.1 - 3e-37 127.1 0.7 1.1e-36 125.4 0.7 2.0 1 0 0 1 1 1 1 SLIDE Helicase_C PF00271.31 RLN94692.1 - 1.7e-21 76.6 0.0 8.9e-21 74.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN94692.1 - 7e-07 29.4 0.0 4.5e-06 26.8 0.0 2.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HAND PF09110.11 RLN94692.1 - 0.0012 19.5 7.4 0.0012 19.5 7.4 2.8 3 0 0 3 3 3 1 HAND AAA_14 PF13173.6 RLN94692.1 - 0.016 15.2 0.1 0.084 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 RLN94692.1 - 0.034 14.0 0.2 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF1451 PF07295.11 RLN94692.1 - 1.7 8.7 7.9 0.43 10.6 0.6 3.1 2 0 0 2 2 2 0 Zinc-ribbon containing domain PUF PF00806.19 RLN94693.1 - 6.7e-11 41.3 0.0 0.04 13.6 0.0 5.6 6 0 0 6 6 6 3 Pumilio-family RNA binding repeat DUF2052 PF09747.9 RLN94693.1 - 0.33 11.0 10.3 9.4 6.3 6.5 2.7 2 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) TPR_1 PF00515.28 RLN94695.1 - 8.3e-09 34.9 1.2 0.0039 17.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN94695.1 - 2e-07 30.6 1.9 0.034 14.3 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN94695.1 - 7.4e-05 22.3 0.5 0.042 13.5 0.1 2.9 1 1 1 2 2 2 2 TPR repeat TPR_8 PF13181.6 RLN94695.1 - 0.062 13.5 0.0 16 6.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN94695.1 - 0.079 13.6 0.4 0.25 12.0 0.4 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN94695.1 - 0.098 13.0 2.8 2.3 8.6 0.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 RLN94695.1 - 0.12 12.8 0.5 0.47 11.0 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN94695.1 - 0.27 11.8 0.1 0.27 11.8 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat HELP PF03451.14 RLN94696.1 - 9.9e-39 131.1 0.6 2.9e-15 55.8 0.0 3.7 3 0 0 3 3 3 3 HELP motif WD40 PF00400.32 RLN94696.1 - 4.6e-34 115.9 69.3 0.011 16.6 0.3 26.1 30 0 0 30 30 30 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN94696.1 - 3.7e-27 94.5 0.1 0.018 15.3 0.0 12.7 9 3 3 12 12 12 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN94696.1 - 5.7e-05 22.2 0.7 8.4 5.2 0.0 4.9 5 0 0 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 RLN94696.1 - 0.00075 18.1 0.1 0.02 13.5 0.0 3.0 2 1 0 3 3 3 1 Cytochrome D1 heme domain PD40 PF07676.12 RLN94696.1 - 0.0029 17.5 3.1 11 6.1 0.0 5.5 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 RLN94696.1 - 0.02 13.6 0.2 4.8 5.7 0.0 3.2 3 1 0 3 3 3 0 Nucleoporin Nup120/160 Yippee-Mis18 PF03226.14 RLN94697.1 - 5.5e-16 58.7 0.1 6.7e-16 58.4 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 RLN94697.1 - 0.045 14.0 0.1 0.056 13.7 0.1 1.2 1 0 0 1 1 1 0 C-terminal domain of RIG-I CEBP_ZZ PF16366.5 RLN94697.1 - 0.056 13.7 0.3 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Dioxygenase_C PF00775.21 RLN94698.1 - 4.4e-08 32.8 0.1 8e-08 31.9 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase NOZZLE PF08744.10 RLN94698.1 - 0.0063 16.0 1.2 0.01 15.4 1.2 1.2 1 0 0 1 1 1 1 Plant transcription factor NOZZLE FYVE PF01363.21 RLN94699.1 - 9e-11 41.8 10.6 9e-11 41.8 10.6 2.0 2 0 0 2 2 2 1 FYVE zinc finger RRM_1 PF00076.22 RLN94699.1 - 4.9e-05 23.1 0.0 0.00015 21.5 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAPS PF04499.15 RLN94699.1 - 0.0093 14.8 0.0 0.0093 14.8 0.0 2.6 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein PH PF00169.29 RLN94699.1 - 0.053 14.0 1.3 1.4 9.4 0.0 3.0 3 0 0 3 3 3 0 PH domain IBR PF01485.21 RLN94699.1 - 0.47 10.7 7.7 1.3 9.3 7.7 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain FYVE_2 PF02318.16 RLN94699.1 - 1.1 9.5 5.3 3.6 7.8 5.3 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger RRM_1 PF00076.22 RLN94700.1 - 7.2e-19 67.4 0.1 4.5e-10 39.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RLN94700.1 - 0.0049 16.7 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 RLN94700.1 - 0.033 13.8 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.12 RLN94700.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Calcipressin Cyclin_N PF00134.23 RLN94701.1 - 1.5e-24 86.1 0.1 1.1e-23 83.4 0.1 2.1 1 1 0 1 1 1 1 Cyclin, N-terminal domain TBCC PF07986.12 RLN94702.1 - 7.9e-31 106.3 6.4 1.1e-30 105.8 6.4 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 RLN94702.1 - 0.0011 18.6 2.0 0.0017 18.0 2.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Cyclin_C PF02984.19 RLN94703.1 - 5.7e-21 74.8 1.0 7e-21 74.5 1.0 1.1 1 0 0 1 1 1 1 Cyclin, C-terminal domain PPR_2 PF13041.6 RLN94704.1 - 9.5e-07 28.9 0.0 0.071 13.3 0.1 5.6 5 1 1 6 6 6 1 PPR repeat family Smr PF01713.21 RLN94704.1 - 2.1e-05 24.8 0.0 6.1e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Smr domain PPR_long PF17177.4 RLN94704.1 - 5.9e-05 22.5 2.1 0.086 12.2 0.3 3.2 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 RLN94704.1 - 0.00011 22.2 0.2 53 4.4 0.0 5.7 6 0 0 6 6 6 0 PPR repeat Ribosomal_S21e PF01249.18 RLN94704.1 - 0.062 13.4 0.2 0.23 11.6 0.2 2.1 1 1 0 1 1 1 0 Ribosomal protein S21e DUF1387 PF07139.11 RLN94704.1 - 0.19 11.4 2.5 0.31 10.7 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) PX PF00787.24 RLN94705.1 - 1.6e-07 31.3 0.4 2.5e-07 30.7 0.4 1.3 1 0 0 1 1 1 1 PX domain Pkinase PF00069.25 RLN94706.1 - 2.9e-49 167.8 0.0 4.2e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN94706.1 - 9.1e-49 166.1 0.0 1.4e-48 165.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Halogen_Hydrol PF10112.9 RLN94706.1 - 0.089 12.8 0.7 0.23 11.5 0.7 1.7 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Kinase-like PF14531.6 RLN94706.1 - 0.13 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like IMPDH PF00478.25 RLN94707.1 - 6.4e-99 331.2 4.5 7.7e-99 331.0 4.5 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 RLN94707.1 - 5.2e-09 35.6 0.8 9.7e-09 34.7 0.8 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 RLN94707.1 - 1.4e-07 31.3 0.9 1.5e-07 31.1 0.9 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 RLN94707.1 - 1.1e-05 25.0 1.7 5.6e-05 22.7 1.7 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 RLN94707.1 - 0.00031 20.1 1.2 0.00057 19.3 1.2 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DUF561 PF04481.12 RLN94707.1 - 0.024 13.8 0.4 0.054 12.7 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF561) NanE PF04131.14 RLN94707.1 - 0.033 13.4 1.1 0.21 10.8 1.1 2.4 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase G3P_antiterm PF04309.12 RLN94707.1 - 0.059 12.8 0.5 0.42 10.0 0.1 2.3 1 1 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Dus PF01207.17 RLN94707.1 - 0.11 11.5 0.5 0.24 10.5 0.2 1.7 1 1 1 2 2 2 0 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 RLN94707.1 - 0.34 10.1 4.0 0.14 11.3 0.9 1.9 2 1 0 2 2 2 0 Dihydroorotate dehydrogenase DUF953 PF06110.11 RLN94708.1 - 1e-32 112.3 0.0 2.5e-22 78.7 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF953) Glutaredoxin PF00462.24 RLN94708.1 - 0.037 14.3 0.2 3.4 7.9 0.0 2.6 2 0 0 2 2 2 0 Glutaredoxin DUF953 PF06110.11 RLN94709.1 - 2.6e-19 69.0 0.0 7.4e-09 35.3 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF953) DUF953 PF06110.11 RLN94710.1 - 8.9e-22 76.9 0.0 1.7e-10 40.5 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF953) DUF953 PF06110.11 RLN94711.1 - 1.2e-24 86.2 0.0 1.9e-12 46.8 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF953) ArfGap PF01412.18 RLN94712.1 - 8.8e-34 116.1 0.0 2.4e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 RLN94712.1 - 2.3e-22 79.9 0.4 8.8e-12 45.2 0.0 2.3 2 0 0 2 2 2 2 BAR domain of APPL family PH PF00169.29 RLN94712.1 - 3.7e-08 33.8 0.0 8.1e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 RLN94712.1 - 3.5e-07 30.6 0.1 1.1e-06 29.1 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN94712.1 - 5.9e-07 29.6 0.5 1.7e-06 28.2 0.5 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN94712.1 - 0.0002 21.9 0.1 0.0007 20.1 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Phage_TAC_11 PF11836.8 RLN94712.1 - 0.045 13.9 0.3 0.045 13.9 0.3 3.1 3 0 0 3 3 3 0 Phage tail tube protein, GTA-gp10 Ank PF00023.30 RLN94712.1 - 0.055 13.9 0.2 0.38 11.3 0.2 2.6 1 0 0 1 1 1 0 Ankyrin repeat Ion_trans PF00520.31 RLN94713.1 - 1.6e-78 263.3 46.7 3.8e-43 147.5 14.9 2.3 2 0 0 2 2 2 2 Ion transport protein EF-hand_1 PF00036.32 RLN94713.1 - 1.7e-11 42.8 4.6 4.4e-06 25.9 1.3 3.0 3 0 0 3 3 3 2 EF hand PKD_channel PF08016.12 RLN94713.1 - 2.3e-11 43.0 31.4 1.6e-06 27.1 10.4 4.1 3 1 0 3 3 3 3 Polycystin cation channel EF-hand_7 PF13499.6 RLN94713.1 - 4.3e-09 36.7 0.1 9.8e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN94713.1 - 3.8e-08 32.6 0.1 0.0053 16.6 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RLN94713.1 - 4.7e-06 25.8 5.4 0.0077 15.7 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 RLN94713.1 - 9.6e-06 25.4 0.3 3e-05 23.8 0.2 2.0 1 1 0 1 1 1 1 EF-hand domain pair TssO PF17561.2 RLN94713.1 - 0.18 11.9 1.2 13 5.8 0.0 2.7 2 0 0 2 2 2 0 Type VI secretion system, TssO DUF2973 PF11189.8 RLN94713.1 - 0.21 11.7 3.7 7.5 6.7 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) FYVE PF01363.21 RLN94714.1 - 8.9e-16 57.8 6.3 1.6e-15 57.0 6.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN94714.1 - 0.021 15.0 4.9 0.021 15.0 4.9 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger START PF01852.19 RLN94715.1 - 1e-14 54.5 0.3 2.5e-14 53.2 0.3 1.6 1 0 0 1 1 1 1 START domain PDZ PF00595.24 RLN94715.1 - 0.003 17.9 0.0 0.0086 16.4 0.0 1.7 2 0 0 2 2 2 1 PDZ domain DUF5421 PF17458.2 RLN94715.1 - 0.011 15.2 0.1 0.019 14.4 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5421) Fe_dep_repr_C PF02742.15 RLN94715.1 - 0.034 14.2 0.0 0.087 12.9 0.0 1.7 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain DUF953 PF06110.11 RLN94716.1 - 1.6e-28 98.7 0.0 8.1e-20 70.6 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF953) Brix PF04427.18 RLN94717.1 - 1.1e-27 97.4 0.0 1.5e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 Brix domain GFO_IDH_MocA PF01408.22 RLN94718.1 - 4.8e-25 88.7 0.1 5.8e-25 88.5 0.1 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 RLN94718.1 - 2.2e-06 28.1 0.1 3.9e-06 27.4 0.1 1.4 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 RLN94718.1 - 2.6e-06 27.8 0.0 4.4e-06 27.1 0.0 1.3 1 1 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_2 PF03446.15 RLN94718.1 - 0.00053 20.2 0.0 0.00087 19.5 0.0 1.4 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 RLN94718.1 - 0.0013 18.2 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 RLN94718.1 - 0.01 16.5 0.1 0.013 16.1 0.1 1.2 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 RLN94718.1 - 0.021 15.1 1.7 1.1 9.5 0.2 2.1 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 RLN94718.1 - 0.022 14.8 0.0 0.053 13.6 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Rossmann-like PF10727.9 RLN94718.1 - 0.036 13.9 0.9 0.054 13.4 0.9 1.4 1 1 0 1 1 1 0 Rossmann-like domain ApbA PF02558.16 RLN94718.1 - 0.051 13.2 0.6 0.18 11.4 0.6 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 RLN94718.1 - 0.1 12.5 2.4 0.26 11.1 2.4 1.8 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CoA_binding PF02629.19 RLN94718.1 - 0.12 13.1 1.2 0.82 10.4 0.1 2.3 1 1 1 2 2 2 0 CoA binding domain IlvN PF07991.12 RLN94718.1 - 0.19 11.3 1.3 12 5.4 0.1 2.1 1 1 1 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DDE_Tnp_4 PF13359.6 RLN94719.1 - 6.3e-07 29.2 1.1 1.2e-06 28.3 1.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 RLN94719.1 - 8.4e-05 22.7 0.3 8.4e-05 22.7 0.3 2.5 3 0 0 3 3 3 1 Transposase zf-BED PF02892.15 RLN94719.1 - 0.00082 19.3 1.5 0.0013 18.7 0.3 2.0 2 0 0 2 2 2 1 BED zinc finger Dimer_Tnp_hAT PF05699.14 RLN94719.1 - 0.0088 15.8 0.0 0.045 13.6 0.1 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DDE_Tnp_1_2 PF13586.6 RLN94719.1 - 0.012 16.0 3.5 0.44 10.9 0.1 3.7 3 0 0 3 3 3 0 Transposase DDE domain DDE_Tnp_1 PF01609.21 RLN94719.1 - 0.084 12.5 1.0 0.14 11.8 0.4 1.7 2 0 0 2 2 2 0 Transposase DDE domain Gla PF00594.20 RLN94720.1 - 0.003 17.7 0.1 0.0073 16.5 0.1 1.6 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Retrotrans_gag PF03732.17 RLN94720.1 - 0.033 14.5 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein SURF2 PF05477.11 RLN94721.1 - 1.9e-16 60.5 0.0 1.9e-16 60.5 0.0 2.2 2 0 0 2 2 2 1 Surfeit locus protein 2 (SURF2) T2SSM PF04612.12 RLN94721.1 - 0.35 10.9 7.7 3.9 7.5 2.5 3.0 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein M GFO_IDH_MocA PF01408.22 RLN94722.1 - 1.7e-16 61.1 0.1 6.2e-16 59.3 0.1 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 RLN94722.1 - 2.1e-07 31.0 0.0 3.5e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain IQ PF00612.27 RLN94723.1 - 7e-06 25.4 0.9 0.0055 16.4 0.0 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif DUF724 PF05266.14 RLN94723.1 - 0.15 11.9 0.0 0.15 11.9 0.0 5.2 4 1 0 5 5 5 0 Protein of unknown function (DUF724) HR1 PF02185.16 RLN94724.1 - 0.14 12.3 0.3 0.26 11.4 0.3 1.5 1 0 0 1 1 1 0 Hr1 repeat fn3 PF00041.21 RLN94725.1 - 2.3e-38 130.4 0.0 6.2e-08 32.9 0.3 6.9 6 0 0 6 6 6 6 Fibronectin type III domain WD40 PF00400.32 RLN94725.1 - 4.7e-21 74.7 4.6 4.3e-07 30.5 0.3 5.2 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN94725.1 - 0.0072 16.6 1.7 1.6 9.1 0.0 4.2 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Pur_ac_phosph_N PF16656.5 RLN94725.1 - 0.2 12.3 2.2 1.2e+02 3.4 0.0 4.7 5 2 0 5 5 5 0 Purple acid Phosphatase, N-terminal domain Abhydrolase_3 PF07859.13 RLN94727.1 - 1e-20 74.5 0.1 2.4e-19 70.0 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 RLN94727.1 - 1.6e-15 57.0 1.1 4.9e-15 55.4 1.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 RLN94727.1 - 4.4e-07 30.7 1.0 8.2e-07 29.8 1.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 RLN94727.1 - 0.0013 18.3 0.1 0.015 14.8 0.0 2.4 3 0 0 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 RLN94727.1 - 0.0037 16.6 0.4 0.021 14.1 0.1 2.3 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 RLN94727.1 - 0.0066 15.4 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 RLN94727.1 - 0.0078 15.9 0.2 0.13 11.9 0.2 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF829 PF05705.14 RLN94727.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Esterase PF00756.20 RLN94727.1 - 0.046 13.4 0.4 0.89 9.1 0.4 2.2 1 1 0 1 1 1 0 Putative esterase Tombus_movement PF05318.12 RLN94727.1 - 0.097 13.5 3.3 0.93 10.4 0.1 3.1 3 0 0 3 3 3 0 Tombusvirus movement protein Mucin PF01456.17 RLN94728.1 - 0.002 18.1 5.4 0.0028 17.7 5.4 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein Podoplanin PF05808.11 RLN94728.1 - 0.0023 18.1 2.0 0.0026 17.9 2.0 1.2 1 0 0 1 1 1 1 Podoplanin Defensin_propep PF00879.18 RLN94728.1 - 0.0056 16.9 1.0 0.011 15.9 1.0 1.6 1 0 0 1 1 1 1 Defensin propeptide DUF4366 PF14283.6 RLN94728.1 - 0.11 12.6 2.4 0.076 13.1 0.7 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) RIFIN PF02009.16 RLN94728.1 - 0.23 11.3 0.3 0.25 11.2 0.3 1.1 1 0 0 1 1 1 0 Rifin MGC-24 PF05283.11 RLN94728.1 - 0.32 11.4 3.9 0.4 11.1 3.9 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF515 PF04415.12 RLN94728.1 - 0.6 8.4 4.8 0.63 8.4 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DLH PF01738.18 RLN94729.1 - 4.1e-19 69.0 0.3 7.1e-19 68.2 0.3 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 RLN94729.1 - 0.0034 16.7 0.0 0.25 10.5 0.0 2.3 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Pkinase PF00069.25 RLN94730.1 - 7e-45 153.5 0.0 8.2e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN94730.1 - 9.4e-28 97.2 0.0 1.4e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN94730.1 - 0.0067 15.3 0.0 0.0095 14.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN94730.1 - 0.011 15.7 0.8 2.3 8.1 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN94730.1 - 0.088 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_15 PF09445.10 RLN94732.1 - 6.2e-16 58.4 0.0 1e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 RLN94732.1 - 0.00027 20.6 0.0 0.00056 19.6 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 FancD2 PF14631.6 RLN94732.1 - 0.48 7.8 2.0 0.32 8.3 0.0 1.5 2 0 0 2 2 2 0 Fanconi anaemia protein FancD2 nuclease G-patch PF01585.23 RLN94733.1 - 1.6e-10 40.7 2.6 1.6e-10 40.7 2.6 2.2 3 0 0 3 3 3 1 G-patch domain zf-C2H2_jaz PF12171.8 RLN94733.1 - 8.3e-06 25.9 3.8 1.6e-05 25.1 3.8 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RLN94733.1 - 0.0011 19.2 0.7 0.0021 18.4 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 RLN94733.1 - 0.012 15.7 4.1 0.021 14.9 4.1 1.4 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_4 PF13894.6 RLN94733.1 - 0.064 14.1 0.4 0.21 12.5 0.4 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger G-patch_2 PF12656.7 RLN94733.1 - 0.56 10.3 3.1 0.64 10.2 0.2 2.7 3 0 0 3 3 3 0 G-patch domain SAE2 PF08573.10 RLN94733.1 - 1.4 10.1 14.5 0.71 11.0 10.5 2.2 1 1 1 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Ion_trans PF00520.31 RLN94734.1 - 0.0021 17.3 19.4 0.018 14.3 19.4 2.1 1 1 0 1 1 1 1 Ion transport protein DUF4446 PF14584.6 RLN94734.1 - 0.0033 17.4 0.6 0.36 10.8 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4446) GIT_CC PF16559.5 RLN94734.1 - 0.071 13.0 0.2 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF948 PF06103.11 RLN94734.1 - 0.072 13.4 1.2 6.6 7.1 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) LppA PF16708.5 RLN94734.1 - 0.095 12.6 0.0 0.26 11.2 0.0 1.6 2 0 0 2 2 2 0 Lipoprotein confined to pathogenic Mycobacterium STAT_alpha PF01017.20 RLN94734.1 - 0.15 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 STAT protein, all-alpha domain COPI_assoc PF08507.10 RLN94735.1 - 5.1e-16 58.9 8.4 6.1e-16 58.7 8.4 1.1 1 0 0 1 1 1 1 COPI associated protein SLATT_6 PF18169.1 RLN94735.1 - 1.2 8.8 3.6 2 8.0 3.6 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 p450 PF00067.22 RLN94736.1 - 1.8e-66 224.8 0.0 2.3e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 RLN94737.1 - 2.9e-11 42.8 0.2 3.1e-11 42.7 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1084 PF06454.11 RLN94738.1 - 0.0025 17.2 3.5 0.004 16.6 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) SpoIISA_toxin PF14171.6 RLN94739.1 - 0.31 10.7 6.0 0.5 10.0 6.0 1.3 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system EF-hand_6 PF13405.6 RLN94740.1 - 4.7e-19 66.6 6.4 0.00011 21.8 0.0 5.1 6 0 0 6 6 6 4 EF-hand domain EF-hand_1 PF00036.32 RLN94740.1 - 8.6e-19 65.6 1.6 0.0014 18.1 0.0 5.0 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 RLN94740.1 - 4.5e-17 62.3 3.5 2.7e-08 34.1 0.5 3.7 3 1 1 4 4 4 3 EF-hand domain pair Tim17 PF02466.19 RLN94740.1 - 2.8e-11 43.7 1.1 5.6e-11 42.8 1.1 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family EF-hand_8 PF13833.6 RLN94740.1 - 4.1e-11 42.6 1.1 2.8e-05 23.9 0.0 5.3 4 1 1 5 5 5 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN94740.1 - 2.3e-09 36.3 2.5 0.13 11.8 0.1 5.1 5 0 0 5 5 5 4 EF hand Caleosin PF05042.13 RLN94740.1 - 0.0012 18.8 0.0 1.9 8.4 0.0 3.5 3 1 1 4 4 4 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 RLN94740.1 - 0.013 15.8 0.2 3.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RLN94740.1 - 0.088 12.8 0.3 0.53 10.3 0.2 2.2 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF2231 PF09990.9 RLN94742.1 - 0.1 13.0 7.7 0.15 12.5 7.7 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) Antimicrobial10 PF08105.11 RLN94742.1 - 0.67 10.1 3.9 13 5.9 0.1 2.6 2 0 0 2 2 2 0 Metchnikowin family DUF4006 PF13179.6 RLN94742.1 - 3.4 7.7 5.6 4.2 7.4 2.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF4006) DUF2749 PF10907.8 RLN94742.1 - 6.9 6.9 5.5 0.67 10.2 0.2 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2749) SdpI PF13630.6 RLN94742.1 - 8.6 6.6 7.4 0.89 9.7 2.6 1.9 2 0 0 2 2 2 0 SdpI/YhfL protein family Pyr_redox_2 PF07992.14 RLN94745.1 - 6.9e-39 133.8 0.0 1.2e-38 133.0 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RLN94745.1 - 0.0005 20.6 0.4 0.0035 17.8 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RLN94745.1 - 0.015 14.5 0.0 0.21 10.7 0.0 2.2 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 RLN94745.1 - 0.071 13.1 0.1 6.8 6.7 0.0 3.5 3 1 1 4 4 4 0 FAD-NAD(P)-binding DUF4459 PF14673.6 RLN94745.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4459) DAO PF01266.24 RLN94745.1 - 0.17 11.4 0.3 14 5.1 0.0 2.8 1 1 2 3 3 3 0 FAD dependent oxidoreductase MIP PF00230.20 RLN94746.1 - 1.2e-39 136.4 9.8 1.2e-38 133.1 9.8 2.4 1 1 0 1 1 1 1 Major intrinsic protein Tmemb_185A PF10269.9 RLN94746.1 - 4.4e-14 52.8 4.5 4.4e-14 52.8 4.5 2.3 2 1 0 2 2 2 1 Transmembrane Fragile-X-F protein DnaJ PF00226.31 RLN94746.1 - 1.1e-11 44.6 0.1 2.3e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Syja_N PF02383.18 RLN94747.1 - 2.9e-66 224.0 0.0 3e-56 191.1 0.0 2.2 1 1 1 2 2 2 2 SacI homology domain DUF1031 PF06275.11 RLN94747.1 - 0.1 12.8 0.3 0.31 11.3 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1031) CwfJ_C_1 PF04677.15 RLN94749.1 - 6.5e-31 106.7 0.0 1.2e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 RLN94749.1 - 1.2e-08 35.7 0.1 2.5e-08 34.7 0.1 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Tmemb_185A PF10269.9 RLN94750.1 - 5.4e-12 45.9 3.8 5.4e-12 45.9 3.8 2.3 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein DUF805 PF05656.14 RLN94750.1 - 0.001 19.4 2.6 0.001 19.4 2.6 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF805) Ank_4 PF13637.6 RLN94751.1 - 1.7e-38 130.5 13.9 1.9e-08 34.7 0.2 8.7 5 2 4 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN94751.1 - 5.6e-37 125.3 22.4 6.6e-09 35.9 2.7 7.4 6 1 1 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN94751.1 - 2.4e-33 114.5 14.1 3.2e-13 50.1 0.7 5.5 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN94751.1 - 6.7e-31 102.9 12.8 0.00072 19.8 0.1 10.6 11 0 0 11 11 11 6 Ankyrin repeat Ank PF00023.30 RLN94751.1 - 3.8e-26 90.3 20.0 0.00049 20.4 0.1 8.7 9 0 0 9 9 9 7 Ankyrin repeat CTP_transf_1 PF01148.20 RLN94752.1 - 4e-36 125.1 24.6 2.4e-35 122.6 16.5 2.3 2 0 0 2 2 2 2 Cytidylyltransferase family CTP_transf_1 PF01148.20 RLN94753.1 - 1.8e-34 119.7 26.1 1.1e-33 117.1 17.4 2.5 2 1 0 2 2 2 2 Cytidylyltransferase family Arv1 PF04161.13 RLN94754.1 - 4.7e-48 164.1 0.3 6.9e-48 163.6 0.3 1.2 1 0 0 1 1 1 1 Arv1-like family DUF4741 PF15897.5 RLN94754.1 - 0.091 12.6 0.1 0.091 12.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4741) TF_Zn_Ribbon PF08271.12 RLN94754.1 - 0.14 11.7 0.5 0.31 10.6 0.5 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Mg_trans_NIPA PF05653.14 RLN94755.1 - 5.5e-12 45.4 9.9 1.7e-09 37.2 0.5 2.2 2 0 0 2 2 2 2 Magnesium transporter NIPA SYS1 PF09801.9 RLN94755.1 - 0.13 12.4 3.1 0.37 10.9 0.1 2.7 2 1 0 2 2 2 0 Integral membrane protein S linking to the trans Golgi network DUF2970 PF11174.8 RLN94755.1 - 0.37 10.7 4.6 4.7 7.1 0.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2970) E1-E2_ATPase PF00122.20 RLN94755.1 - 1 8.9 3.4 0.4 10.2 0.1 2.0 2 1 0 2 2 2 0 E1-E2 ATPase DUF805 PF05656.14 RLN94755.1 - 1.7 9.1 11.4 1.4 9.4 7.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF805) CTP_transf_1 PF01148.20 RLN94756.1 - 4e-37 128.4 21.6 1e-35 123.8 15.1 2.6 2 1 0 2 2 2 2 Cytidylyltransferase family DUF5489 PF17592.2 RLN94756.1 - 0.4 11.3 0.0 0.4 11.3 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5489) YfhO PF09586.10 RLN94756.1 - 2.8 6.0 7.4 4 5.5 7.4 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO ResB PF05140.14 RLN94756.1 - 7.8 5.1 5.5 1.1 7.9 1.4 1.6 2 0 0 2 2 2 0 ResB-like family Nnf1 PF03980.14 RLN94757.1 - 3.2e-14 53.3 18.0 1.1e-13 51.5 18.0 1.9 1 1 0 1 1 1 1 Nnf1 CRIC_ras_sig PF10534.9 RLN94757.1 - 0.014 15.6 5.9 0.04 14.1 1.0 2.7 2 1 1 3 3 3 0 Connector enhancer of kinase suppressor of ras Evr1_Alr PF04777.13 RLN94757.1 - 0.037 14.5 0.4 0.086 13.3 0.1 1.8 2 0 0 2 2 2 0 Erv1 / Alr family Pepsin-I3 PF06394.13 RLN94757.1 - 0.15 12.2 4.6 0.085 13.1 2.2 1.8 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain Fzo_mitofusin PF04799.13 RLN94757.1 - 0.5 9.9 9.3 0.56 9.7 4.3 2.1 2 0 0 2 2 2 0 fzo-like conserved region zf-CpG_bind_C PF12269.8 RLN94757.1 - 0.68 9.7 8.8 1.4 8.7 4.3 2.1 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain DUF1382 PF07131.11 RLN94757.1 - 0.73 9.9 5.2 1.3 9.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1382) DUF148 PF02520.17 RLN94757.1 - 1.2 9.3 9.3 7.6 6.7 3.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF148 Sigma70_ner PF04546.13 RLN94757.1 - 1.2 9.0 14.1 0.86 9.4 12.6 1.5 1 1 0 1 1 1 0 Sigma-70, non-essential region bZIP_1 PF00170.21 RLN94757.1 - 1.4 9.1 12.3 0.17 12.0 6.5 2.4 2 1 1 3 3 3 0 bZIP transcription factor HsdM_N PF12161.8 RLN94757.1 - 2.6 8.7 5.9 3.5 8.3 5.1 1.6 1 1 1 2 2 2 0 HsdM N-terminal domain Spc7 PF08317.11 RLN94757.1 - 5.7 5.7 17.2 3.8 6.3 14.5 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Mannosyl_trans3 PF11051.8 RLN94758.1 - 3.8e-29 101.9 0.0 4.9e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative NAM-associated PF14303.6 RLN94762.1 - 4.2 8.0 7.9 6.7 7.4 6.9 1.9 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Y_phosphatase PF00102.27 RLN94763.1 - 5.7e-54 183.2 0.0 9.3e-54 182.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CTP_transf_1 PF01148.20 RLN94763.1 - 3.9e-35 121.9 18.1 1e-34 120.5 11.6 2.4 2 0 0 2 2 2 2 Cytidylyltransferase family DSPc PF00782.20 RLN94763.1 - 6.1e-05 22.8 0.1 0.00013 21.8 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Pkinase PF00069.25 RLN94765.1 - 8e-45 153.3 0.0 1.4e-44 152.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN94765.1 - 3.9e-38 131.2 0.0 7.4e-38 130.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 RLN94765.1 - 8.5e-06 26.0 4.3 0.00025 21.4 0.1 3.3 1 1 3 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN94765.1 - 0.00024 20.8 4.6 0.00026 20.7 2.8 2.0 2 0 0 2 2 2 1 Leucine rich repeat CD34_antigen PF06365.12 RLN94765.1 - 0.0064 16.1 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family Haspin_kinase PF12330.8 RLN94765.1 - 0.059 12.3 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain DUF4604 PF15377.6 RLN94768.1 - 0.51 10.8 19.7 1.3 9.5 19.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) PRTP PF01366.18 RLN94768.1 - 4 5.4 5.0 5 5.0 5.0 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein CDC45 PF02724.14 RLN94768.1 - 4.7 5.4 11.4 5.8 5.1 11.4 1.0 1 0 0 1 1 1 0 CDC45-like protein BRCT PF00533.26 RLN94769.1 - 2.5e-12 47.0 0.0 7e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 RLN94769.1 - 4.4e-09 36.9 0.1 1.6e-08 35.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 RLN94769.1 - 2.9e-06 27.1 0.0 6.2e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 RLN94769.1 - 0.00018 21.5 0.8 0.00018 21.5 0.8 2.7 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 RLN94769.1 - 0.00023 21.6 0.1 0.0011 19.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 RLN94769.1 - 0.0031 18.1 0.0 0.0031 18.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 RLN94769.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_5 PF07728.14 RLN94769.1 - 0.0051 16.8 0.3 0.021 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 RLN94769.1 - 0.0053 16.9 0.0 0.02 15.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 RLN94769.1 - 0.0078 16.1 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 NTPase TIP49 PF06068.13 RLN94769.1 - 0.014 14.6 0.0 0.014 14.6 0.0 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain TsaE PF02367.17 RLN94769.1 - 0.024 14.6 0.0 0.059 13.4 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GREB1 PF15782.5 RLN94769.1 - 0.026 11.7 10.6 0.053 10.6 10.6 1.4 1 1 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AAA_28 PF13521.6 RLN94769.1 - 0.033 14.4 0.1 0.092 13.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain PTCB-BRCT PF12738.7 RLN94769.1 - 0.035 14.0 0.0 0.079 12.9 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain RNA_helicase PF00910.22 RLN94769.1 - 0.043 14.2 0.1 0.25 11.7 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 RLN94769.1 - 0.055 13.0 0.1 0.12 11.8 0.1 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 RLN94769.1 - 0.063 13.6 0.6 0.17 12.1 0.0 2.1 3 0 0 3 3 1 0 AAA domain Mg_chelatase PF01078.21 RLN94769.1 - 0.073 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 RLN94769.1 - 0.11 12.4 0.0 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 RLN94769.1 - 0.13 12.7 0.0 0.13 12.7 0.0 3.0 2 1 1 3 3 2 0 AAA domain ABC_tran PF00005.27 RLN94769.1 - 0.44 11.1 0.1 0.44 11.1 0.1 3.1 2 1 1 3 3 2 0 ABC transporter CDC45 PF02724.14 RLN94769.1 - 0.55 8.5 19.8 1 7.6 19.8 1.4 1 0 0 1 1 1 0 CDC45-like protein AAA_23 PF13476.6 RLN94769.1 - 2.4 8.6 20.2 6.8 7.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain Nuc_sug_transp PF04142.15 RLN94770.1 - 2.9e-105 351.9 8.8 3.3e-105 351.7 8.8 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 RLN94770.1 - 4.5e-09 35.9 7.8 6.8e-09 35.3 7.8 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 RLN94770.1 - 6.4e-07 29.6 21.8 0.00035 20.8 3.6 2.4 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 RLN94770.1 - 0.00074 18.8 11.6 0.0018 17.6 11.6 1.7 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport DUF4229 PF14012.6 RLN94770.1 - 0.81 9.8 6.3 3.1 8.0 2.9 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) CTC1 PF15489.6 RLN94771.1 - 2e-06 25.7 0.0 4.1e-06 24.6 0.0 1.4 1 0 0 1 1 1 1 CST, telomere maintenance, complex subunit CTC1 Ank_2 PF12796.7 RLN94775.1 - 3.9e-32 110.7 0.0 2.2e-15 57.0 0.0 5.4 4 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 RLN94775.1 - 1.3e-25 88.6 11.9 9.8e-07 29.0 0.0 8.8 8 0 0 8 8 8 5 Ankyrin repeat TIR_2 PF13676.6 RLN94775.1 - 8.9e-25 87.6 0.5 4e-18 66.1 0.1 3.6 3 0 0 3 3 3 3 TIR domain Ank_3 PF13606.6 RLN94775.1 - 1.6e-23 80.2 3.7 0.0004 20.6 0.0 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 RLN94775.1 - 5.8e-22 77.5 13.2 2.5e-06 27.6 0.1 7.0 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN94775.1 - 2e-21 76.1 8.6 4.4e-07 30.3 0.1 7.6 6 1 2 8 8 8 5 Ankyrin repeats (many copies) TIR PF01582.20 RLN94775.1 - 0.00088 19.1 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 TIR domain RWP-RK PF02042.15 RLN94776.1 - 8e-21 73.8 0.0 1.7e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 RWP-RK domain TrkA_N PF02254.18 RLN94778.1 - 0.11 12.8 0.3 0.14 12.5 0.3 1.2 1 0 0 1 1 1 0 TrkA-N domain Nop14 PF04147.12 RLN94778.1 - 1.1 7.3 3.6 1.2 7.2 3.6 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 RLN94778.1 - 2.1 6.4 7.2 2.4 6.1 7.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi PDZ PF00595.24 RLN94780.1 - 0.05 14.0 0.0 0.094 13.1 0.0 1.5 1 0 0 1 1 1 0 PDZ domain RWP-RK PF02042.15 RLN94781.1 - 1.3e-20 73.1 0.1 2.7e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain UDPGT PF00201.18 RLN94783.1 - 2.8e-10 39.6 0.0 4.7e-09 35.6 0.0 2.0 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 RLN94783.1 - 0.0097 15.9 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain TIR_2 PF13676.6 RLN94784.1 - 2.4e-09 37.8 0.0 0.00089 19.8 0.0 2.4 2 0 0 2 2 2 2 TIR domain Selenoprotein_S PF06936.11 RLN94784.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) Dehydrin PF00257.19 RLN94784.1 - 0.16 12.5 6.9 0.73 10.4 2.8 2.4 2 0 0 2 2 2 0 Dehydrin DUF1863 PF08937.11 RLN94784.1 - 0.17 12.2 0.1 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) TUDOR PF00567.24 RLN94785.1 - 4e-09 36.5 0.0 0.0013 18.7 0.0 2.5 2 1 1 3 3 3 2 Tudor domain Agenet PF05641.12 RLN94785.1 - 0.0018 18.7 0.4 0.28 11.7 0.0 2.7 2 1 0 2 2 2 1 Agenet domain SMN PF06003.12 RLN94785.1 - 0.002 17.5 1.0 0.0041 16.4 0.0 1.9 1 1 0 2 2 2 1 Survival motor neuron protein (SMN) Tudor_2 PF18104.1 RLN94785.1 - 0.1 12.3 0.1 15 5.3 0.0 2.5 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain Cullin PF00888.22 RLN94786.1 - 1.5e-200 668.0 4.2 2e-200 667.5 4.2 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 RLN94786.1 - 3.4e-28 97.5 1.4 1.1e-27 95.8 1.4 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain Spy1 PF11357.8 RLN94788.1 - 0.0064 16.8 0.0 0.87 9.9 0.0 2.5 2 0 0 2 2 2 2 Cell cycle regulatory protein cNMP_binding PF00027.29 RLN94789.1 - 4e-19 68.5 0.0 3.3e-09 36.7 0.0 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN94789.1 - 1.6e-17 63.5 15.5 6.5e-12 45.2 6.3 2.5 2 0 0 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 RLN94789.1 - 9.5e-09 35.1 19.3 2.6e-06 27.3 4.5 3.5 3 0 0 3 3 3 2 Ion channel YqhR PF11085.8 RLN94789.1 - 0.0095 15.9 0.2 0.0095 15.9 0.2 2.6 3 0 0 3 3 3 1 Conserved membrane protein YqhR DUF3082 PF11282.8 RLN94789.1 - 0.018 15.3 4.3 0.99 9.7 0.0 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3082) COX6C PF02937.15 RLN94789.1 - 6.8 6.9 9.7 0.96 9.6 0.4 3.8 4 0 0 4 4 4 0 Cytochrome c oxidase subunit VIc HEAT PF02985.22 RLN94790.1 - 1.5e-21 74.6 18.1 0.0015 18.7 0.3 10.4 11 1 1 12 12 12 6 HEAT repeat HEAT_2 PF13646.6 RLN94790.1 - 7.6e-15 55.1 0.5 0.0073 16.7 0.3 6.1 2 2 3 5 5 5 3 HEAT repeats Vac14_Fab1_bd PF12755.7 RLN94790.1 - 0.00047 20.7 0.0 0.54 10.9 0.0 4.4 2 1 3 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 RLN94790.1 - 0.00065 20.2 2.4 2.6 8.7 0.0 4.9 2 1 2 4 4 4 1 HEAT-like repeat Cnd1 PF12717.7 RLN94790.1 - 0.0014 18.7 0.0 0.34 10.9 0.0 3.0 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DNA_alkylation PF08713.11 RLN94790.1 - 0.014 15.1 0.0 2 8.1 0.0 2.7 1 1 1 2 2 2 0 DNA alkylation repair enzyme CLASP_N PF12348.8 RLN94790.1 - 0.046 13.3 0.1 2.4 7.7 0.0 2.7 2 1 0 2 2 2 0 CLASP N terminal RuvX PF03652.15 RLN94791.1 - 0.0098 16.3 0.3 0.021 15.2 0.3 1.5 1 0 0 1 1 1 1 Holliday junction resolvase DUF2218 PF09981.9 RLN94791.1 - 0.07 13.5 1.6 8.1 6.9 0.2 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2218) DUF3638 PF12340.8 RLN94792.1 - 9.2e-57 192.0 0.0 1.7e-56 191.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) Transcrip_reg PF01709.20 RLN94793.1 - 2.9e-50 170.9 1.7 7.4e-42 143.4 0.0 2.2 1 1 1 2 2 2 2 Transcriptional regulator Vinculin PF01044.19 RLN94793.1 - 0.075 11.3 0.3 0.096 10.9 0.3 1.1 1 0 0 1 1 1 0 Vinculin family Trp_repressor PF01371.19 RLN94796.1 - 0.034 14.3 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 Trp repressor protein CaM_bdg_C0 PF10562.9 RLN94796.1 - 0.093 12.8 0.6 0.19 11.8 0.6 1.5 1 1 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Pepdidase_M14_N PF18027.1 RLN94798.1 - 4.5e-10 39.9 0.1 1e-09 38.7 0.1 1.6 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 RLN94798.1 - 0.00027 20.8 0.0 0.0006 19.7 0.0 1.5 1 1 0 1 1 1 1 Zinc carboxypeptidase MMR_HSR1 PF01926.23 RLN94799.1 - 2.6e-18 66.2 0.0 5e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RLN94799.1 - 2.5e-05 24.2 0.3 0.0028 17.6 0.0 2.6 2 1 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 RLN94799.1 - 8.4e-05 22.2 0.0 0.00019 21.0 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Septin PF00735.18 RLN94799.1 - 0.00014 21.2 0.0 0.011 15.1 0.0 2.2 1 1 0 1 1 1 1 Septin Dynamin_N PF00350.23 RLN94799.1 - 0.00022 21.3 0.2 0.0051 16.9 0.1 2.3 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 RLN94799.1 - 0.00095 18.8 0.1 0.2 11.2 0.0 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.10 RLN94799.1 - 0.026 14.0 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 RLN94799.1 - 0.11 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 RLN94799.1 - 0.17 12.4 0.0 0.37 11.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter CobW_C PF07683.14 RLN94800.1 - 0.01 15.7 0.3 0.052 13.5 0.1 2.2 2 0 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain RNA_pol_Rpc4 PF05132.14 RLN94800.1 - 0.17 12.3 4.6 0.37 11.2 4.6 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 SpoIIIAH PF12685.7 RLN94800.1 - 2.1 8.1 8.1 0.95 9.3 2.3 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein GTP1_OBG PF01018.22 RLN94800.1 - 4.7 6.8 9.9 2.3 7.8 0.1 2.5 2 0 0 2 2 2 0 GTP1/OBG SR-25 PF10500.9 RLN94804.1 - 1.5 8.4 10.8 0.12 12.0 2.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Suppressor_APC PF11414.8 RLN94804.1 - 3.4 7.8 8.0 3.8 7.6 1.6 3.1 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Dimeth_Pyl PF09505.10 RLN94805.1 - 0.047 12.2 0.0 0.068 11.7 0.0 1.1 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) DUF2205 PF10224.9 RLN94806.1 - 0.017 15.1 0.3 0.048 13.7 0.3 1.7 1 0 0 1 1 1 0 Short coiled-coil protein Pur_ac_phosph_N PF16656.5 RLN94809.1 - 7.1e-14 52.1 3.4 1e-12 48.5 0.2 2.6 2 1 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain tRNA-synt_1e PF01406.19 RLN94810.1 - 3.6e-13 49.5 0.1 4.2e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain TauD PF02668.16 RLN94811.1 - 2.4e-33 116.1 2.4 7.2e-20 71.9 0.1 2.0 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family RNA_pol_Rpb5_N PF03871.14 RLN94812.1 - 0.041 14.5 0.1 0.058 14.0 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain DUF4253 PF14062.6 RLN94812.1 - 0.072 13.3 0.0 0.084 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) DUF3235 PF11574.8 RLN94813.1 - 0.22 12.4 5.0 20 6.1 0.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3235) FlxA PF14282.6 RLN94813.1 - 1.4 9.0 11.5 1.4 9.0 9.3 2.1 2 0 0 2 2 2 0 FlxA-like protein GAS PF13851.6 RLN94813.1 - 6.7 6.0 13.2 5.7 6.2 7.9 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ABC_tran PF00005.27 RLN94814.1 - 1.7e-28 99.9 0.0 2.8e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 RLN94814.1 - 2.5e-19 69.6 28.9 2.8e-18 66.1 28.9 2.4 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 RLN94814.1 - 1.3e-12 48.2 0.1 1.9e-08 34.5 0.0 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RLN94814.1 - 0.0012 19.4 0.0 0.0022 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 RLN94814.1 - 0.0016 18.3 0.1 0.0044 17.0 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN94814.1 - 0.013 15.3 0.2 0.029 14.1 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 RLN94814.1 - 0.041 13.6 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DLIC PF05783.11 RLN94814.1 - 0.042 12.7 0.1 0.24 10.2 0.0 1.9 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) ABC2_membrane_5 PF13346.6 RLN94814.1 - 0.061 12.9 17.2 0.12 11.9 17.2 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane PF01061.24 RLN94814.1 - 0.066 12.6 27.3 0.13 11.6 18.6 2.7 3 0 0 3 3 3 0 ABC-2 type transporter SMC_N PF02463.19 RLN94814.1 - 0.075 12.5 0.0 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 RLN94814.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain TPR_10 PF13374.6 RLN94815.1 - 5.7 6.9 6.9 1.6 8.7 0.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Kinesin PF00225.23 RLN94816.1 - 7.4e-107 357.1 0.9 9.2e-107 356.8 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RLN94816.1 - 4.3e-25 88.4 0.0 1e-24 87.2 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding FAM76 PF16046.5 RLN94816.1 - 0.18 11.1 9.3 0.014 14.8 4.6 1.5 2 0 0 2 2 2 0 FAM76 protein ResIII PF04851.15 RLN94816.1 - 0.29 11.1 0.0 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit FapA PF03961.13 RLN94816.1 - 0.31 9.6 4.4 0.48 9.0 4.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Pkinase PF00069.25 RLN94817.1 - 1.4e-48 165.5 0.0 3.2e-46 157.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN94817.1 - 6.3e-15 55.2 0.0 5.1e-14 52.2 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN94817.1 - 0.012 14.9 0.0 0.96 8.7 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 RLN94817.1 - 0.051 12.9 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RLN94817.1 - 0.063 12.9 0.1 0.23 11.0 0.1 1.9 1 1 0 1 1 1 0 Choline/ethanolamine kinase Thioredoxin_8 PF13905.6 RLN94818.1 - 2.6e-23 82.2 0.0 3.4e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 RLN94818.1 - 1.8e-08 34.3 0.0 2.5e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 RLN94818.1 - 1.3e-07 31.6 0.0 4.1e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_9 PF14595.6 RLN94818.1 - 7.5e-06 25.7 0.0 0.00039 20.2 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Redoxin PF08534.10 RLN94818.1 - 7.4e-05 22.5 0.0 9.5e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 RLN94818.1 - 0.0025 18.2 0.0 0.0047 17.3 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain STAS_2 PF13466.6 RLN94818.1 - 0.012 16.0 0.2 0.075 13.4 0.1 2.3 3 1 1 4 4 4 0 STAS domain Thioredoxin_7 PF13899.6 RLN94818.1 - 0.012 15.8 0.0 0.045 13.9 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like SCO1-SenC PF02630.14 RLN94818.1 - 0.037 13.9 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 SCO1/SenC Glutaredoxin PF00462.24 RLN94818.1 - 0.1 12.9 0.0 0.45 10.8 0.0 2.1 1 1 0 1 1 1 0 Glutaredoxin PLAC8 PF04749.17 RLN94818.1 - 0.11 13.5 0.0 0.17 12.9 0.0 1.3 1 0 0 1 1 1 0 PLAC8 family DUF953 PF06110.11 RLN94818.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) RHH_1 PF01402.21 RLN94819.1 - 0.26 11.3 1.9 19 5.4 0.0 2.5 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Thioredoxin_8 PF13905.6 RLN94820.1 - 6.2e-16 58.5 0.0 8.8e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 RLN94820.1 - 0.00075 19.4 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family IQ PF00612.27 RLN94821.1 - 2.3e-08 33.1 26.4 0.0026 17.4 0.0 6.5 6 0 0 6 6 6 4 IQ calmodulin-binding motif Phi-29_GP4 PF05464.11 RLN94821.1 - 0.032 14.5 0.0 0.43 10.8 0.0 2.3 2 0 0 2 2 2 0 Phi-29-like late genes activator (early protein GP4) Exo_endo_phos PF03372.23 RLN94822.1 - 2.9e-15 56.4 0.0 4.4e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ku PF02735.16 RLN94823.1 - 7.9e-43 146.5 0.0 1.4e-42 145.7 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 RLN94823.1 - 4.8e-24 84.8 0.3 2.9e-23 82.3 0.0 2.3 2 0 0 2 2 2 1 Ku C terminal domain like Ku_N PF03731.15 RLN94823.1 - 5.1e-05 23.1 2.2 0.00016 21.5 0.2 2.4 3 0 0 3 3 3 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 RLN94823.1 - 8e-05 23.3 0.1 0.00075 20.1 0.0 2.7 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm DUF3632 PF12311.8 RLN94823.1 - 0.024 15.1 1.5 2.5 8.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3632) V-ATPase_G PF03179.15 RLN94823.1 - 0.095 13.2 0.3 0.47 11.0 0.3 2.2 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit WGG PF10273.9 RLN94824.1 - 9e-19 67.9 0.1 2.2e-18 66.7 0.0 1.7 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 RLN94824.1 - 0.094 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RNase_Zc3h12a PF11977.8 RLN94825.1 - 8.2e-18 64.7 0.0 1.6e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PRORP PF16953.5 RLN94825.1 - 0.00092 18.8 0.2 0.009 15.6 0.2 2.0 2 0 0 2 2 2 1 Protein-only RNase P KH_1 PF00013.29 RLN94825.1 - 0.0099 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 KH domain DUF5615 PF18480.1 RLN94825.1 - 0.041 13.6 0.4 0.15 11.8 0.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5615) PhageP22-tail PF09251.10 RLN94825.1 - 0.14 10.5 0.0 0.21 9.9 0.0 1.2 1 0 0 1 1 1 0 Salmonella phage P22 tail-spike TPR_1 PF00515.28 RLN94826.1 - 2.4e-14 52.5 5.4 2e-05 24.2 0.3 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN94826.1 - 7.4e-13 47.6 10.2 0.00011 22.1 0.3 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN94826.1 - 4.2e-12 45.6 9.9 1.9e-07 30.6 0.7 2.8 3 0 0 3 3 3 2 TPR repeat TPR_17 PF13431.6 RLN94826.1 - 7e-10 38.6 1.4 0.00019 21.6 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN94826.1 - 2.1e-07 30.6 5.2 0.093 13.0 0.2 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN94826.1 - 3e-05 24.5 17.6 0.012 16.3 0.1 5.3 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN94826.1 - 0.0019 18.8 13.0 0.043 14.5 1.3 4.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN94826.1 - 0.0048 17.4 13.1 0.0093 16.5 0.7 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat DnaJ PF00226.31 RLN94826.1 - 0.017 15.2 1.8 0.21 11.7 0.0 3.4 2 1 1 3 3 3 0 DnaJ domain TOM20_plant PF06552.12 RLN94826.1 - 0.33 10.7 11.3 1.4 8.6 0.2 3.0 3 1 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_6 PF13174.6 RLN94826.1 - 4.6 8.1 9.7 24 5.8 0.1 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat Sugar_tr PF00083.24 RLN94829.1 - 1.3e-104 350.6 18.1 1.5e-104 350.4 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN94829.1 - 1.2e-26 93.5 27.8 1.7e-18 66.7 6.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RLN94829.1 - 0.00085 18.0 0.7 0.00085 18.0 0.7 3.0 3 0 0 3 3 3 2 MFS/sugar transport protein BT1 PF03092.16 RLN94829.1 - 0.012 13.9 0.3 0.012 13.9 0.3 2.1 2 0 0 2 2 2 0 BT1 family Gly-zipper_Omp PF13488.6 RLN94829.1 - 0.28 11.2 3.8 1.5 8.9 0.5 2.8 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.15 RLN94829.1 - 0.81 9.6 4.0 0.88 9.5 0.9 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain DUF423 PF04241.15 RLN94829.1 - 6.2 7.1 8.3 4.9 7.4 0.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF423) DUF3054 PF11255.8 RLN94829.1 - 7.1 7.2 11.1 1.4 9.4 0.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3054) bPH_1 PF08000.11 RLN94830.1 - 5e-19 68.6 0.0 7.6e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial PH domain GrpE PF01025.19 RLN94831.1 - 1.1 9.0 5.0 4.2 7.0 0.0 2.6 1 1 0 2 2 2 0 GrpE Chromate_transp PF02417.15 RLN94832.1 - 1.2e-46 158.7 36.7 1.1e-37 129.6 17.5 3.4 2 1 0 2 2 2 2 Chromate transporter AcrZ PF10766.9 RLN94832.1 - 0.0024 17.4 0.9 0.0088 15.6 0.9 2.0 1 0 0 1 1 1 1 Multidrug efflux pump-associated protein AcrZ Phage_holin_3_1 PF05106.12 RLN94832.1 - 0.067 13.6 5.8 1.2 9.6 0.3 2.6 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) DUF4134 PF13572.6 RLN94832.1 - 2.4 8.5 9.3 1.9 8.8 0.2 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4134) Glyco_hydro_30 PF02055.16 RLN94833.1 - 5.7e-25 88.0 0.2 7.3e-25 87.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 RLN94833.1 - 1.4e-17 63.6 0.3 1.9e-17 63.2 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain SpoIIAA-like PF11964.8 RLN94833.1 - 0.12 13.4 0.0 0.15 13.1 0.0 1.2 1 0 0 1 1 1 0 SpoIIAA-like Sec10 PF07393.11 RLN94840.1 - 1.9e-48 165.5 1.0 2.3e-48 165.2 1.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Med21 PF11221.8 RLN94840.1 - 3.7 7.8 6.6 23 5.2 0.1 3.3 3 1 0 3 3 3 0 Subunit 21 of Mediator complex HTH_23 PF13384.6 RLN94845.1 - 0.0083 15.9 0.6 0.039 13.8 0.6 2.0 1 1 0 1 1 1 1 Homeodomain-like domain DUF1351 PF07083.11 RLN94845.1 - 0.02 14.7 0.0 0.027 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) KORA PF16509.5 RLN94845.1 - 0.049 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor Phage_NinH PF06322.11 RLN94845.1 - 0.09 12.7 0.1 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Phage NinH protein WD40 PF00400.32 RLN94846.1 - 7.7e-34 115.2 21.4 5.2e-07 30.3 0.3 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN94846.1 - 2.3e-12 47.0 0.2 0.094 13.0 0.0 5.3 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RLN94846.1 - 0.0064 15.9 0.4 0.37 10.1 0.1 3.2 2 1 1 3 3 3 1 WD40-like domain EF-hand_1 PF00036.32 RLN94847.1 - 3.3e-23 79.5 0.1 0.00022 20.6 0.0 6.5 6 0 0 6 6 6 5 EF hand EF-hand_7 PF13499.6 RLN94847.1 - 1.3e-21 76.8 0.2 1.8e-06 28.3 0.1 3.7 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RLN94847.1 - 1.3e-17 62.1 3.9 0.0057 16.5 0.0 6.4 6 0 0 6 6 6 4 EF-hand domain EF-hand_5 PF13202.6 RLN94847.1 - 1.1e-12 46.8 2.6 0.00016 21.0 0.1 5.6 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 RLN94847.1 - 5.6e-08 32.5 0.0 0.2 11.5 0.0 5.3 5 0 0 5 5 5 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RLN94847.1 - 0.00024 21.4 0.5 0.29 11.5 0.0 4.3 5 0 0 5 5 5 1 Secreted protein acidic and rich in cysteine Ca binding region BST2 PF16716.5 RLN94847.1 - 0.0066 17.0 0.5 0.015 15.9 0.5 1.5 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 CRR7 PF12095.8 RLN94847.1 - 0.05 14.0 0.3 0.16 12.4 0.3 1.9 1 1 1 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 ChlamPMP_M PF07548.11 RLN94847.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain MYCBPAP PF14646.6 RLN94848.1 - 0.29 10.0 4.3 0.46 9.4 4.3 1.3 1 0 0 1 1 1 0 MYCBP-associated protein family TSNAXIP1_N PF15739.5 RLN94850.1 - 2e-10 41.0 0.2 2.4e-09 37.5 0.0 2.9 2 1 1 3 3 3 1 Translin-associated factor X-interacting N-terminus KORA PF16509.5 RLN94850.1 - 0.04 14.2 0.0 0.21 11.9 0.0 2.3 1 1 0 1 1 1 0 TrfB plasmid transcriptional repressor DUF4200 PF13863.6 RLN94850.1 - 0.11 12.9 7.0 0.29 11.5 7.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) ATP-synt_DE PF00401.20 RLN94850.1 - 1.6 9.0 7.7 1.9 8.8 3.2 2.9 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Ferric_reduct PF01794.19 RLN94851.1 - 1.3e-17 64.1 12.9 1.3e-17 64.1 12.9 2.8 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 RLN94851.1 - 1.1e-16 61.3 0.0 4e-16 59.5 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 RLN94851.1 - 2.3e-10 40.5 0.0 4.2e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain WTF PF03303.13 RLN94851.1 - 0.011 15.5 0.1 0.011 15.5 0.1 1.9 2 0 0 2 2 2 0 WTF protein DUF2207 PF09972.9 RLN94851.1 - 0.14 10.9 0.0 0.14 10.9 0.0 3.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) TMEM132D_C PF15706.5 RLN94851.1 - 2.6 7.9 4.4 4 7.3 0.1 2.7 2 1 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF3671 PF12420.8 RLN94851.1 - 3.1 7.9 4.1 21 5.2 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function RIO1 PF01163.22 RLN94852.1 - 2.4e-38 131.6 0.0 7.6e-36 123.5 0.0 2.2 1 1 0 1 1 1 1 RIO1 family Pkinase PF00069.25 RLN94852.1 - 4.6e-06 26.2 0.0 6.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN94852.1 - 0.022 14.0 0.2 0.082 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase VWA_3 PF13768.6 RLN94852.1 - 0.11 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain CCDC50_N PF15295.6 RLN94852.1 - 0.66 10.1 3.9 0.26 11.5 1.0 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus FYVE PF01363.21 RLN94853.1 - 1.5e-15 57.1 8.0 1.5e-15 57.1 8.0 3.4 3 1 0 3 3 3 1 FYVE zinc finger WW PF00397.26 RLN94853.1 - 1.3e-12 47.5 0.3 7.7e-12 45.1 0.1 2.3 2 0 0 2 2 2 1 WW domain zf-LSD1 PF06943.12 RLN94853.1 - 0.00033 20.4 3.7 0.00033 20.4 3.7 3.6 3 0 0 3 3 3 1 LSD1 zinc finger Arm PF00514.23 RLN94853.1 - 0.0035 17.3 7.5 3.9 7.7 0.2 6.6 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Methyltransf_23 PF13489.6 RLN94853.1 - 0.0047 16.8 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN94853.1 - 0.006 17.3 0.0 0.041 14.6 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN94853.1 - 0.017 15.7 0.0 0.071 13.8 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 RLN94853.1 - 0.033 13.7 0.0 0.081 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain N6_Mtase PF02384.16 RLN94853.1 - 0.053 12.8 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 N-6 DNA Methylase HypA PF01155.19 RLN94853.1 - 6.6 6.8 20.6 2.8 8.0 0.4 4.8 4 0 0 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Asn_synthase PF00733.21 RLN94854.1 - 6.4e-19 68.8 0.0 8.3e-15 55.3 0.1 2.2 1 1 1 2 2 2 2 Asparagine synthase MMACHC PF16690.5 RLN94854.1 - 0.026 14.2 0.0 1.2 8.7 0.0 2.5 3 0 0 3 3 3 0 Methylmalonic aciduria and homocystinuria type C family MiAMP1 PF09117.10 RLN94855.1 - 0.0026 18.0 0.4 3.1 8.1 0.0 2.8 2 1 1 3 3 3 2 MiAMP1 Inhibitor_I36 PF03995.13 RLN94855.1 - 0.0041 17.0 9.0 0.0084 16.0 1.1 3.0 2 1 1 3 3 3 2 Peptidase inhibitor family I36 Pertus-S4-tox PF09275.10 RLN94855.1 - 0.095 13.0 0.0 2.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Pertussis toxin S4 subunit Oscp1 PF10188.9 RLN94856.1 - 2.7e-67 226.3 4.1 3.7e-67 225.8 4.1 1.2 1 0 0 1 1 1 1 Organic solute transport protein 1 Inhibitor_I36 PF03995.13 RLN94859.1 - 0.0011 18.8 1.2 0.0026 17.6 1.1 1.7 1 1 1 2 2 2 1 Peptidase inhibitor family I36 2-Hacid_dh_C PF02826.19 RLN94860.1 - 2.1e-43 147.7 0.0 3.1e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 RLN94860.1 - 6.3e-07 29.7 0.0 1.1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 RLN94860.1 - 0.001 19.1 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Rossmann-like PF10727.9 RLN94860.1 - 0.0044 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Rossmann-like domain IlvN PF07991.12 RLN94860.1 - 0.0069 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 RLN94860.1 - 0.0073 16.9 0.0 0.017 15.7 0.0 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.21 RLN94860.1 - 0.11 11.8 0.6 0.46 9.8 0.2 1.9 1 1 1 2 2 2 0 ThiF family PIF6 PF05341.11 RLN94860.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Per os infectivity factor 6 NAD_Gly3P_dh_N PF01210.23 RLN94860.1 - 0.14 12.1 0.2 2.3 8.2 0.2 2.2 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 RLN94860.1 - 0.16 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PPR_2 PF13041.6 RLN94862.1 - 2.5e-18 66.0 0.0 1.2 9.4 0.0 11.7 11 2 1 12 12 12 3 PPR repeat family PPR PF01535.20 RLN94862.1 - 1.1e-13 50.4 8.4 0.2 12.0 0.0 12.5 14 1 0 14 14 14 2 PPR repeat PPR_long PF17177.4 RLN94862.1 - 1e-07 31.5 7.7 0.0067 15.8 1.5 6.1 3 1 4 7 7 7 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 RLN94862.1 - 6.7e-05 22.9 0.0 15 5.7 0.0 6.6 5 2 2 8 8 8 0 Pentatricopeptide repeat domain TPR_19 PF14559.6 RLN94862.1 - 0.00022 21.7 26.8 0.47 11.0 1.5 8.4 8 0 0 8 8 8 2 Tetratricopeptide repeat PPR_1 PF12854.7 RLN94862.1 - 0.0054 16.4 2.1 50 3.7 0.0 6.6 8 0 0 8 8 8 0 PPR repeat TPR_7 PF13176.6 RLN94862.1 - 0.026 14.6 11.1 1.2 9.4 0.0 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN94862.1 - 0.043 14.5 6.5 0.47 11.2 0.0 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN94862.1 - 0.13 12.4 0.1 56 4.2 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 RLN94862.1 - 0.52 11.1 11.3 13 6.7 0.2 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN94862.1 - 1.3 10.0 30.1 9.5 7.3 0.0 10.9 12 1 1 13 13 11 0 Tetratricopeptide repeat DUF3408 PF11888.8 RLN94862.1 - 3 8.0 5.5 7.6 6.7 5.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Crystall PF00030.19 RLN94863.1 - 0.021 15.0 0.3 0.094 12.9 0.3 2.1 1 1 0 1 1 1 0 Beta/Gamma crystallin COesterase PF00135.28 RLN94864.1 - 2.2e-100 337.0 0.4 5.6e-100 335.6 0.4 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RLN94864.1 - 0.0003 20.7 0.0 0.0003 20.7 0.0 2.4 3 0 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN94864.1 - 0.0061 16.1 0.2 0.0061 16.1 0.2 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Tannase PF07519.11 RLN94865.1 - 4.3e-128 428.2 0.0 7.6e-128 427.4 0.0 1.3 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 RLN94865.1 - 0.003 17.1 0.1 2.2 7.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Mito_carr PF00153.27 RLN94867.1 - 7.8e-68 224.5 7.4 8.5e-27 92.9 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 RLN94867.1 - 0.041 13.0 3.8 0.37 9.9 0.0 2.9 3 1 0 3 3 3 0 Gammaproteobacterial serine protease SyrA PF11089.8 RLN94867.1 - 0.12 12.5 1.7 0.13 12.3 0.1 2.0 2 0 0 2 2 2 0 Exopolysaccharide production repressor DUF1295 PF06966.12 RLN94868.1 - 1.8e-59 201.1 2.5 2.4e-59 200.7 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 RLN94868.1 - 1e-07 32.0 0.1 2.1e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 RLN94868.1 - 0.00013 22.3 0.4 0.00056 20.3 0.1 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 RLN94868.1 - 0.00089 19.6 0.1 0.00089 19.6 0.1 2.9 2 1 1 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 RLN94868.1 - 0.039 12.7 0.2 0.2 10.4 0.2 2.1 1 1 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family TipAS PF07739.13 RLN94868.1 - 0.06 13.9 0.2 0.11 13.1 0.2 1.4 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Ribo_biogen_C PF04034.13 RLN94869.1 - 7.2e-51 171.2 0.0 1e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 RLN94869.1 - 1.7e-09 37.3 0.4 2.8e-09 36.6 0.4 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Hist_deacetyl PF00850.19 RLN94870.1 - 1.1e-60 205.7 0.0 2.1e-60 204.8 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Ank_2 PF12796.7 RLN94870.1 - 7.5e-07 29.7 0.1 0.23 12.1 0.0 4.1 3 2 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN94870.1 - 2.9e-05 24.2 0.7 1.6 9.2 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN94870.1 - 4.1e-05 24.0 0.6 0.76 10.4 0.0 3.9 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN94870.1 - 0.00017 21.7 2.1 86 4.2 0.1 6.1 6 0 0 6 6 6 0 Ankyrin repeat B12-binding PF02310.19 RLN94870.1 - 0.063 13.3 0.0 9.9 6.2 0.0 2.5 2 0 0 2 2 2 0 B12 binding domain Ank PF00023.30 RLN94870.1 - 0.34 11.4 2.9 42 4.8 0.1 4.4 5 0 0 5 5 5 0 Ankyrin repeat IMS PF00817.20 RLN94877.1 - 9.3e-37 126.3 0.1 1.6e-36 125.6 0.1 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 RLN94877.1 - 1.5e-15 57.9 0.0 5.4e-15 56.1 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 RLN94877.1 - 1.2e-06 27.8 2.8 7.5e-06 25.2 0.0 3.2 3 0 0 3 3 3 1 Ubiquitin binding region BRCT PF00533.26 RLN94877.1 - 5.1e-05 23.6 0.0 0.00022 21.5 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.8 RLN94877.1 - 0.00055 20.1 0.0 0.0016 18.7 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif BRCT_2 PF16589.5 RLN94877.1 - 0.0023 18.3 0.0 0.0062 16.9 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 RLN94877.1 - 0.0039 17.1 0.1 0.011 15.7 0.1 1.8 1 0 0 1 1 1 1 twin BRCT domain FTA4 PF13093.6 RLN94877.1 - 0.12 12.3 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Acyltransferase PF01553.21 RLN94878.1 - 1.4e-05 24.8 0.0 2.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase RCC1 PF00415.18 RLN94879.1 - 3.1e-53 178.2 17.7 8e-15 55.2 0.2 8.7 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN94879.1 - 1.1e-22 79.3 39.5 3.8e-06 26.6 1.0 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat AMP-binding PF00501.28 RLN94880.1 - 1e-64 218.7 0.0 3.3e-64 217.1 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 RLN94880.1 - 9.2e-16 57.5 7.4 2.6e-14 52.9 7.4 2.6 1 1 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 RLN94880.1 - 4.7e-05 24.3 0.0 0.00015 22.7 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3357 PF11837.8 RLN94881.1 - 0.01 16.3 0.4 0.041 14.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DUF805 PF05656.14 RLN94881.1 - 0.081 13.3 1.3 0.21 12.0 1.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF805) GTP_cyclohydroI PF01227.22 RLN94882.1 - 1.9e-77 258.7 1.4 2.4e-77 258.4 1.4 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 RLN94882.1 - 0.003 17.7 0.0 0.0055 16.8 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein SUD-M PF11633.8 RLN94882.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Single-stranded poly(A) binding domain RNA_binding PF01877.17 RLN94882.1 - 0.034 14.4 0.1 0.068 13.4 0.1 1.5 1 0 0 1 1 1 0 RNA binding EF-hand_6 PF13405.6 RLN94883.1 - 1.8e-10 39.9 13.9 0.53 10.4 0.0 8.5 8 0 0 8 8 8 4 EF-hand domain EF-hand_7 PF13499.6 RLN94883.1 - 1.1e-08 35.4 6.8 0.67 10.4 0.0 7.3 7 0 0 7 7 7 3 EF-hand domain pair EF-hand_1 PF00036.32 RLN94883.1 - 0.00026 20.3 16.7 1.7 8.4 0.1 7.2 8 0 0 8 8 8 3 EF hand RST PF12174.8 RLN94883.1 - 1.2 9.1 20.2 5.7 6.9 0.0 8.2 8 2 1 9 9 9 0 RCD1-SRO-TAF4 (RST) plant domain Rad21_Rec8_N PF04825.13 RLN94884.1 - 3e-40 136.8 0.0 5.8e-40 135.9 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 RLN94884.1 - 5.8e-14 51.1 0.2 2.2e-13 49.2 0.2 2.0 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein CNDH2_N PF06278.11 RLN94884.1 - 0.041 14.1 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DnaJ PF00226.31 RLN94885.1 - 1.7e-11 44.1 0.0 2.9e-11 43.3 0.0 1.5 1 1 0 1 1 1 1 DnaJ domain DUF1455 PF07306.11 RLN94886.1 - 0.026 14.5 0.7 0.063 13.2 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) PDEase_I PF00233.19 RLN94887.1 - 2.2e-66 224.0 0.6 2.9e-66 223.6 0.6 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase FlxA PF14282.6 RLN94888.1 - 0.01 15.8 2.1 0.014 15.4 2.1 1.2 1 0 0 1 1 1 0 FlxA-like protein RRM_1 PF00076.22 RLN94889.1 - 1.4e-42 143.4 0.0 1.4e-17 63.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN94889.1 - 0.0007 19.7 0.0 1.6 8.9 0.0 3.2 2 1 1 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 RLN94889.1 - 0.00082 19.3 0.0 0.0031 17.5 0.0 2.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 RLN94889.1 - 0.017 15.4 0.0 0.45 10.7 0.0 2.7 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 RLN94889.1 - 0.038 14.1 0.0 0.21 11.6 0.0 2.0 2 0 0 2 2 2 0 RNA binding motif OB_RNB PF08206.11 RLN94889.1 - 0.15 11.8 0.5 23 4.8 0.1 2.7 2 0 0 2 2 2 0 Ribonuclease B OB domain RRM_occluded PF16842.5 RLN94889.1 - 0.17 11.7 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif FYVE PF01363.21 RLN94890.1 - 1.8 8.8 14.0 0.77 9.9 10.7 2.0 2 0 0 2 2 2 0 FYVE zinc finger DZR PF12773.7 RLN94890.1 - 3.3 7.8 9.1 0.24 11.5 3.1 2.2 2 0 0 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 RLN94891.1 - 0.0053 17.1 2.5 0.012 15.9 2.5 1.6 1 0 0 1 1 1 1 C1 domain FYVE PF01363.21 RLN94891.1 - 0.0089 16.1 15.7 0.018 15.1 15.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE PF01363.21 RLN94892.1 - 1e-13 51.2 27.7 1.4e-10 41.1 6.4 2.7 2 0 0 2 2 2 2 FYVE zinc finger START PF01852.19 RLN94892.1 - 5.8e-06 25.9 0.6 0.00011 21.6 0.1 2.4 2 0 0 2 2 2 1 START domain FYVE_2 PF02318.16 RLN94892.1 - 0.16 12.1 26.6 0.064 13.5 3.3 3.5 3 0 0 3 3 3 0 FYVE-type zinc finger ArfGap PF01412.18 RLN94892.1 - 1.9 8.6 8.0 1.9 8.6 3.7 3.2 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf AAA_32 PF13654.6 RLN94892.1 - 7.2 5.3 9.9 3.9 6.2 2.4 2.4 2 0 0 2 2 2 0 AAA domain CBS PF00571.28 RLN94894.1 - 3.1e-05 24.3 0.0 4.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 CBS domain RR_TM4-6 PF06459.12 RLN94894.1 - 0.54 10.0 6.2 0.57 10.0 6.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cation_efflux PF01545.21 RLN94895.1 - 1e-43 149.4 7.0 1.3e-43 149.1 7.0 1.1 1 0 0 1 1 1 1 Cation efflux family N1221 PF07923.13 RLN94895.1 - 0.23 10.6 0.0 0.4 9.8 0.0 1.3 1 0 0 1 1 1 0 N1221-like protein SelP_N PF04592.14 RLN94895.1 - 6.8 6.0 20.6 7.2 5.9 7.6 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region ApbA_C PF08546.11 RLN94896.1 - 0.04 14.1 0.5 0.056 13.6 0.5 1.4 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Cmc1 PF08583.10 RLN94897.1 - 2.2e-12 46.8 4.9 2.7e-12 46.5 4.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 RLN94897.1 - 0.51 10.6 6.1 1.3 9.3 4.6 2.2 1 1 2 3 3 3 0 CHCH domain OrfB_Zn_ribbon PF07282.11 RLN94898.1 - 0.0049 16.8 0.1 0.016 15.2 0.1 1.8 1 0 0 1 1 1 1 Putative transposase DNA-binding domain DUF5364 PF17322.2 RLN94898.1 - 0.34 11.2 16.3 0.4 11.0 1.4 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5364) WD40 PF00400.32 RLN94899.1 - 3.4e-10 40.4 4.8 0.0021 18.8 0.0 6.7 6 0 0 6 6 6 3 WD domain, G-beta repeat HELP PF03451.14 RLN94899.1 - 6e-06 26.0 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 HELP motif TetR_C_11 PF16859.5 RLN94900.1 - 0.00022 21.5 1.3 4.6 7.6 0.1 4.0 3 1 0 3 3 3 2 Tetracyclin repressor-like, C-terminal domain DUF2613 PF11021.8 RLN94900.1 - 0.0014 18.7 11.0 1.1 9.4 0.2 4.5 3 0 0 3 3 3 3 Protein of unknown function (DUF2613) RNA_pol_Rpb2_45 PF10385.9 RLN94900.1 - 0.49 10.7 2.4 99 3.3 0.0 4.6 6 0 0 6 6 6 0 RNA polymerase beta subunit external 1 domain Leu_zip PF15294.6 RLN94901.1 - 1.2e-11 44.7 44.8 4.7e-07 29.6 1.7 3.8 4 1 0 5 5 5 3 Leucine zipper Ank_4 PF13637.6 RLN94901.1 - 2.6e-06 27.8 0.0 0.0028 18.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN94901.1 - 0.0015 19.0 0.0 0.96 10.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN94901.1 - 0.0035 17.7 0.3 3 8.7 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat DUF948 PF06103.11 RLN94901.1 - 0.061 13.6 1.4 0.18 12.1 1.4 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Ank PF00023.30 RLN94901.1 - 0.16 12.5 0.1 3.4 8.3 0.1 2.8 2 0 0 2 2 2 0 Ankyrin repeat DAGK_cat PF00781.24 RLN94902.1 - 1.5e-21 76.3 0.0 2.8e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Pkinase PF00069.25 RLN94903.1 - 5e-43 147.4 0.0 7.9e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN94903.1 - 6.6e-24 84.6 0.0 1e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN94903.1 - 0.0072 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 RLN94903.1 - 0.03 13.3 0.2 0.048 12.6 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 RLN94903.1 - 0.66 8.7 2.9 1.9 7.2 2.9 1.9 1 1 0 1 1 1 0 Fungal protein kinase V-SNARE_C PF12352.8 RLN94904.1 - 3.9e-17 62.3 3.8 8.9e-17 61.1 3.8 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 RLN94904.1 - 1.5e-07 31.2 0.3 1.5e-07 31.2 0.3 2.1 3 1 0 3 3 3 1 Sec20 CENP-T_C PF15511.6 RLN94904.1 - 0.036 14.2 0.1 0.064 13.4 0.1 1.6 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold PLAC9 PF15205.6 RLN94904.1 - 0.053 13.9 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Placenta-specific protein 9 Dict-STAT-coil PF09267.10 RLN94904.1 - 0.72 10.3 3.5 0.5 10.8 0.2 2.3 2 1 1 3 3 3 0 Dictyostelium STAT, coiled coil DUF2011 PF09428.10 RLN94905.1 - 0.004 17.4 0.3 0.05 13.8 0.1 2.5 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) PH PF00169.29 RLN94906.1 - 1e-18 67.8 0.1 1.2e-18 67.6 0.1 1.1 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 RLN94906.1 - 1.1e-05 25.5 0.0 1.4e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 RLN94906.1 - 4.4e-05 23.8 0.4 0.0033 17.8 0.4 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 RLN94906.1 - 0.0001 22.6 3.5 0.0053 17.2 3.5 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 RLN94906.1 - 0.00053 20.2 0.1 0.00076 19.7 0.1 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 RLN94906.1 - 0.015 15.1 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain PH_2 PF08458.10 RLN94906.1 - 0.027 14.8 0.1 0.042 14.2 0.1 1.5 1 1 0 1 1 1 0 Plant pleckstrin homology-like region PIP5K PF01504.18 RLN94907.1 - 9.5e-67 225.1 0.0 1.7e-66 224.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_2 PF00002.24 RLN94907.1 - 0.00065 19.1 4.5 0.0015 17.9 4.5 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Yip1 PF04893.17 RLN94907.1 - 0.25 11.1 6.7 0.072 12.8 0.5 2.3 2 0 0 2 2 2 0 Yip1 domain SNARE_assoc PF09335.11 RLN94909.1 - 0.034 14.6 0.0 0.11 12.9 0.1 1.7 2 0 0 2 2 2 0 SNARE associated Golgi protein ATP-synt_I PF03899.15 RLN94909.1 - 0.052 13.9 0.1 0.078 13.4 0.1 1.2 1 0 0 1 1 1 0 ATP synthase I chain bZIP_1 PF00170.21 RLN94911.1 - 0.0012 18.9 5.8 0.0012 18.9 5.8 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 RLN94911.1 - 0.058 13.5 8.7 0.07 13.2 6.5 2.2 2 0 0 2 2 2 0 Basic region leucine zipper CCDC23 PF15674.5 RLN94911.1 - 0.3 11.1 3.7 0.65 10.0 3.7 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 23 MatE PF01554.18 RLN94912.1 - 7.4e-56 188.2 31.0 4.2e-31 107.8 13.0 2.9 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 RLN94912.1 - 0.0011 19.1 30.4 0.013 15.6 14.0 3.4 2 1 1 3 3 3 2 Polysaccharide biosynthesis C-terminal domain bZIP_1 PF00170.21 RLN94913.1 - 0.015 15.4 10.5 0.019 15.1 6.8 2.4 2 0 0 2 2 2 0 bZIP transcription factor CCDC23 PF15674.5 RLN94913.1 - 0.12 12.4 5.8 0.29 11.1 5.8 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 23 bZIP_2 PF07716.15 RLN94913.1 - 0.5 10.5 18.1 0.094 12.8 9.1 2.7 3 0 0 3 3 3 0 Basic region leucine zipper Actin PF00022.19 RLN94914.1 - 1.2e-88 297.5 0.0 7.7e-88 294.8 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 RLN94914.1 - 0.084 11.7 0.0 0.12 11.1 0.0 1.4 1 1 0 1 1 1 0 MreB/Mbl protein MatE PF01554.18 RLN94915.1 - 3.7e-61 205.5 23.9 1.1e-31 109.7 6.1 2.9 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 RLN94915.1 - 0.00015 21.9 11.5 0.00015 21.9 11.5 3.8 3 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain LicD PF04991.13 RLN94916.1 - 3.4e-11 43.7 0.0 1.7e-07 31.6 0.0 2.1 2 0 0 2 2 2 2 LicD family G6PD_C PF02781.16 RLN94917.1 - 1.1e-25 90.5 0.2 6.8e-23 81.3 0.0 3.0 2 1 0 2 2 2 2 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 RLN94917.1 - 2e-07 31.8 0.0 8.6e-06 26.5 0.0 2.6 1 1 1 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain PhyH PF05721.13 RLN94918.1 - 3.6e-06 27.4 0.1 4.4e-06 27.1 0.1 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HIRA_B PF09453.10 RLN94918.1 - 0.13 12.1 0.8 0.29 11.0 0.8 1.6 1 0 0 1 1 1 0 HIRA B motif RPAP1_C PF08620.10 RLN94919.1 - 1.7e-23 82.5 0.2 6.1e-23 80.7 0.2 2.0 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 RLN94919.1 - 9.6e-16 57.3 0.8 4.4e-15 55.2 0.8 2.3 1 0 0 1 1 1 1 RPAP1-like, N-terminal 2OG-FeII_Oxy_3 PF13640.6 RLN94922.1 - 9.8e-07 29.6 0.1 0.012 16.4 0.0 2.4 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 RLN94923.1 - 1.9e-07 31.9 0.1 0.0022 18.9 0.0 2.5 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily DUF3416 PF11896.8 RLN94923.1 - 0.056 13.7 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3416) 2OG-FeII_Oxy_3 PF13640.6 RLN94925.1 - 3.8e-08 34.1 0.0 0.00055 20.8 0.0 2.6 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Cse1 PF08506.10 RLN94926.1 - 4e-127 424.1 0.6 6.7e-127 423.3 0.6 1.4 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 RLN94926.1 - 1.1e-110 370.1 0.1 3.4e-110 368.6 0.0 1.9 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 RLN94926.1 - 7.6e-16 57.8 0.1 2.5e-15 56.2 0.1 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT PF02985.22 RLN94926.1 - 0.0024 18.0 0.4 12 6.5 0.1 4.3 3 0 0 3 3 3 1 HEAT repeat Xpo1 PF08389.12 RLN94926.1 - 0.0026 17.8 2.3 0.037 14.1 0.3 4.1 4 1 0 4 4 4 1 Exportin 1-like protein HEAT_2 PF13646.6 RLN94926.1 - 0.035 14.5 0.1 22 5.6 0.0 3.2 2 0 0 2 2 2 0 HEAT repeats Ank_2 PF12796.7 RLN94927.1 - 6.6e-39 132.4 6.5 8.4e-12 45.5 0.3 5.8 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN94927.1 - 1.9e-32 107.7 8.8 0.00012 22.2 0.0 9.2 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 RLN94927.1 - 2.8e-32 110.7 6.3 2.7e-09 37.4 0.2 6.8 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 RLN94927.1 - 6.6e-31 105.4 12.4 8.8e-06 25.9 0.0 9.4 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 RLN94927.1 - 2.1e-30 104.3 13.4 1.1e-06 28.8 0.0 8.2 4 3 6 10 10 10 8 Ankyrin repeats (many copies) BTB PF00651.31 RLN94927.1 - 6.1e-12 45.7 0.0 2.9e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Cupin_8 PF13621.6 RLN94929.1 - 5e-59 200.1 0.0 6.2e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 RLN94929.1 - 9e-06 25.4 0.0 0.073 12.5 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein Sigma70_ner PF04546.13 RLN94929.1 - 2 8.2 10.0 3.8 7.3 10.0 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region TPR_2 PF07719.17 RLN94930.1 - 3.9e-32 107.8 14.2 1.7e-07 30.8 0.0 8.1 7 1 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 RLN94930.1 - 5.9e-32 108.2 19.9 4.4e-08 32.6 0.2 8.5 8 1 0 8 8 8 5 Tetratricopeptide repeat DnaJ PF00226.31 RLN94930.1 - 6.6e-25 87.0 3.0 6.6e-25 87.0 3.0 2.0 2 0 0 2 2 2 1 DnaJ domain TPR_16 PF13432.6 RLN94930.1 - 5.2e-23 81.4 1.0 1e-05 26.1 0.0 4.8 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN94930.1 - 2.8e-22 78.1 14.3 7.7e-05 22.3 1.1 7.5 4 3 3 7 7 7 5 TPR repeat TPR_17 PF13431.6 RLN94930.1 - 4.8e-15 54.8 9.0 6.8e-05 23.0 0.1 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN94930.1 - 5.3e-15 55.7 13.4 2.7e-07 31.0 0.0 5.5 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 RLN94930.1 - 2e-13 49.4 15.4 0.00041 20.3 0.0 7.7 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 RLN94930.1 - 1.6e-12 47.1 11.8 0.019 15.7 0.0 7.6 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 RLN94930.1 - 2.2e-12 46.1 8.1 0.06 13.4 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 RLN94930.1 - 2.4e-12 47.0 16.3 0.0005 20.3 0.2 5.3 4 3 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 RLN94930.1 - 1.8e-07 31.2 6.2 1.9e-05 24.7 0.1 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN94930.1 - 1.4e-06 28.5 16.7 7.9e-05 22.8 0.1 4.6 3 1 3 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 RLN94930.1 - 3.3e-06 27.6 5.6 0.12 12.8 0.7 4.8 1 1 3 6 6 6 4 Bacterial transcriptional activator domain SRP_TPR_like PF17004.5 RLN94930.1 - 2.2e-05 24.5 6.8 0.079 13.0 0.1 4.1 1 1 2 3 3 3 2 Putative TPR-like repeat TPR_6 PF13174.6 RLN94930.1 - 2.4e-05 24.7 17.7 0.026 15.2 0.1 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN94930.1 - 0.00017 21.4 5.9 0.031 14.2 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3856 PF12968.7 RLN94930.1 - 0.0024 17.9 2.9 0.12 12.4 0.5 4.3 4 1 1 5 5 5 1 Domain of Unknown Function (DUF3856) TPR_15 PF13429.6 RLN94930.1 - 0.0052 16.0 4.5 0.054 12.7 0.0 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat Coatomer_E PF04733.14 RLN94930.1 - 0.0073 15.7 0.1 0.022 14.2 0.1 1.9 1 1 0 1 1 1 1 Coatomer epsilon subunit HrpB1_HrpK PF09613.10 RLN94930.1 - 0.01 15.5 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) Mhr1 PF12829.7 RLN94930.1 - 0.023 14.8 0.1 0.046 13.8 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination TPR_4 PF07721.14 RLN94930.1 - 0.028 15.0 2.9 0.69 10.7 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat MIT PF04212.18 RLN94930.1 - 0.038 14.0 14.3 0.58 10.3 0.3 5.9 5 1 1 6 6 6 0 MIT (microtubule interacting and transport) domain HEAT_2 PF13646.6 RLN94930.1 - 0.043 14.2 0.2 0.49 10.8 0.0 2.4 2 0 0 2 2 2 0 HEAT repeats DUF5588 PF17826.1 RLN94930.1 - 0.078 11.8 2.3 0.49 9.2 0.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5588) Fis1_TPR_C PF14853.6 RLN94930.1 - 0.095 12.8 4.8 6.6 6.9 0.0 4.4 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 RLN94930.1 - 0.11 11.8 2.5 2.1 7.7 0.2 3.1 3 1 0 3 3 3 0 MalT-like TPR region FAT PF02259.23 RLN94930.1 - 0.14 11.4 3.9 0.18 11.0 2.0 2.2 2 1 0 2 2 1 0 FAT domain Mito_carr PF00153.27 RLN94931.1 - 3.3e-54 180.8 6.4 7.4e-19 67.5 0.6 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 RLN94931.1 - 0.018 14.2 2.4 0.24 10.5 0.3 2.3 1 1 0 2 2 2 0 Gammaproteobacterial serine protease Oxidored_FMN PF00724.20 RLN94934.1 - 4e-79 266.3 0.0 4.6e-79 266.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF190 PF02641.15 RLN94934.1 - 0.093 13.1 0.1 0.39 11.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized ACR, COG1993 PGM1_C PF18105.1 RLN94934.1 - 0.12 11.9 1.5 36 4.0 0.2 3.7 4 0 0 4 4 4 0 PGM1 C-terminal domain Peptidase_S8 PF00082.22 RLN94935.1 - 8.2e-39 133.6 9.1 1.8e-38 132.5 9.1 1.6 1 1 0 1 1 1 1 Subtilase family Oxidored_FMN PF00724.20 RLN94936.1 - 1.2e-81 274.6 0.0 1.6e-81 274.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PA PF02225.22 RLN94937.1 - 0.00052 20.0 0.1 0.0022 18.0 0.0 2.1 2 0 0 2 2 2 1 PA domain Lustrin_cystein PF14625.6 RLN94937.1 - 0.17 12.3 4.3 0.14 12.6 2.7 1.7 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain FYVE PF01363.21 RLN94938.1 - 3.1e-15 56.1 14.6 6.8e-15 55.0 14.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger eIF-3_zeta PF05091.12 RLN94939.1 - 1 8.3 9.4 1.1 8.1 9.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SOG2 PF10428.9 RLN94939.1 - 2 7.5 9.7 1.8 7.7 9.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1765 PF08578.10 RLN94940.1 - 8.6e-05 23.0 4.4 0.00019 21.9 4.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Sporozoite_P67 PF05642.11 RLN94940.1 - 7 4.6 7.5 14 3.7 7.5 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hydro_7 PF00840.20 RLN94941.1 - 1.7e-121 406.0 9.5 1.7e-121 406.0 9.5 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 7 PPP4R2 PF09184.11 RLN94941.1 - 0.83 9.2 11.9 1.2 8.7 11.9 1.3 1 0 0 1 1 1 0 PPP4R2 Catalase PF00199.19 RLN94943.1 - 6.5e-189 627.9 0.0 1e-188 627.2 0.0 1.3 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 RLN94943.1 - 1.4e-20 73.2 0.2 4e-20 71.8 0.1 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive Atu4866 PF11512.8 RLN94943.1 - 0.29 11.5 2.2 0.3 11.5 0.4 1.9 2 0 0 2 2 2 0 Agrobacterium tumefaciens protein Atu4866 Tannase PF07519.11 RLN94944.1 - 5.1e-120 401.5 0.1 6.8e-120 401.1 0.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 RLN94944.1 - 7.4e-05 22.3 0.1 0.1 12.1 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family OrfB_Zn_ribbon PF07282.11 RLN94945.1 - 9.4e-09 35.1 0.2 2.4e-08 33.8 0.2 1.7 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 RLN94945.1 - 9.9e-05 22.6 3.4 0.00027 21.2 3.4 1.8 1 0 0 1 1 1 1 Probable transposase DVL PF08137.12 RLN94945.1 - 0.0019 18.0 0.1 0.0047 16.7 0.1 1.7 1 0 0 1 1 1 1 DVL family DNA_topoisoIV PF00521.20 RLN94945.1 - 0.032 13.1 0.9 0.048 12.6 0.9 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A NAD_binding_10 PF13460.6 RLN94946.1 - 3.9e-12 46.4 0.0 3.9e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 RLN94946.1 - 9.2e-10 38.5 0.0 1e-09 38.3 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 RLN94946.1 - 0.14 12.0 0.0 0.23 11.4 0.0 1.4 1 1 0 1 1 1 0 KR domain BT1 PF03092.16 RLN94947.1 - 2.1e-10 39.5 1.3 2.1e-10 39.5 1.3 2.4 2 0 0 2 2 2 1 BT1 family PUCC PF03209.15 RLN94947.1 - 0.009 15.0 13.7 0.22 10.5 13.7 2.3 1 1 0 1 1 1 1 PUCC protein SPECT1 PF18680.1 RLN94947.1 - 0.25 11.0 0.0 0.41 10.3 0.0 1.2 1 0 0 1 1 1 0 Plasmodium host cell traversal SPECT1 Mannitol_dh_C PF08125.13 RLN94949.1 - 2.4e-06 27.2 0.1 4e-05 23.2 0.1 2.1 1 1 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Big_6 PF17936.1 RLN94949.1 - 0.035 14.4 0.8 0.099 12.9 0.8 1.8 1 0 0 1 1 1 0 Bacterial Ig domain WD40 PF00400.32 RLN94950.1 - 3.9e-06 27.5 0.2 0.00037 21.2 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat CDP-OH_P_transf PF01066.21 RLN94951.1 - 8.8e-15 55.2 0.0 8.8e-15 55.2 0.0 3.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase UQ_con PF00179.26 RLN94952.1 - 3.6e-10 39.6 0.7 8.3e-10 38.5 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme DUF3450 PF11932.8 RLN94952.1 - 0.0098 15.2 1.3 0.0098 15.2 1.3 3.8 2 1 0 3 3 3 1 Protein of unknown function (DUF3450) Spt20 PF12090.8 RLN94952.1 - 0.011 15.4 5.5 0.011 15.4 5.5 1.9 2 0 0 2 2 2 0 Spt20 family Ndc1_Nup PF09531.10 RLN94952.1 - 0.11 11.2 1.0 0.24 10.0 1.0 1.6 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup XAP5 PF04921.14 RLN94953.1 - 5.7e-34 118.0 8.2 5.7e-34 118.0 8.2 2.0 1 1 1 2 2 2 1 XAP5, circadian clock regulator Inos-1-P_synth PF01658.17 RLN94953.1 - 0.077 13.3 8.0 0.88 9.9 1.4 2.7 1 1 2 3 3 3 0 Myo-inositol-1-phosphate synthase Phostensin PF13914.6 RLN94953.1 - 0.23 12.1 0.2 0.23 12.1 0.2 2.3 2 1 0 2 2 2 0 Phostensin PP1-binding and SH3-binding region XRN_M PF17846.1 RLN94953.1 - 1.5 7.7 9.8 3.4 6.5 10.0 1.6 1 1 0 1 1 1 0 Xrn1 helical domain LMBR1 PF04791.16 RLN94953.1 - 5.2 5.9 4.3 6.4 5.6 4.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein MULE PF10551.9 RLN94954.1 - 8.7e-12 45.3 0.5 7.9e-11 42.2 0.0 2.6 2 1 1 3 3 3 1 MULE transposase domain Transposase_mut PF00872.18 RLN94954.1 - 2.4e-05 23.4 0.3 4e-05 22.7 0.3 1.3 1 0 0 1 1 1 1 Transposase, Mutator family DUF1681 PF07933.14 RLN94957.1 - 1.2e-39 135.4 0.0 1.5e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) SLY PF12485.8 RLN94957.1 - 0.19 12.5 0.8 0.31 11.8 0.8 1.2 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein UMPH-1 PF05822.12 RLN94958.1 - 1.9e-65 220.9 0.1 2.9e-34 118.7 0.1 2.0 2 0 0 2 2 2 2 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 RLN94958.1 - 3e-05 24.5 0.4 0.00092 19.7 0.4 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 RLN94959.1 - 8e-10 38.6 0.0 9.4e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) PKD_channel PF08016.12 RLN94960.1 - 4.7e-10 38.7 1.0 6.1e-10 38.3 1.0 1.1 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 RLN94960.1 - 0.00084 18.6 0.4 0.0011 18.3 0.4 1.1 1 0 0 1 1 1 1 Ion transport protein TMCO5 PF14992.6 RLN94960.1 - 0.00093 18.8 0.2 0.002 17.8 0.2 1.5 1 1 0 1 1 1 1 TMCO5 family CDH1_2_SANT_HL1 PF18375.1 RLN94960.1 - 0.23 12.2 0.3 0.23 12.2 0.3 2.3 3 0 0 3 3 3 0 CDH1/2 SANT-Helical linker 1 Pkinase PF00069.25 RLN94961.1 - 1.6e-69 234.2 0.0 2.1e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN94961.1 - 1.3e-37 129.5 0.0 1.7e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN94961.1 - 0.00061 19.2 0.2 0.037 13.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 RLN94961.1 - 0.00096 18.6 1.4 0.0025 17.2 1.4 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3243 PF11588.8 RLN94962.1 - 0.13 12.6 0.1 0.73 10.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3243) RecO_N PF11967.8 RLN94962.1 - 0.14 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Recombination protein O N terminal UMPH-1 PF05822.12 RLN94963.1 - 2e-53 181.5 0.1 2.2e-53 181.3 0.1 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 RLN94963.1 - 0.00023 21.6 0.0 0.0004 20.8 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase bZIP_1 PF00170.21 RLN94964.1 - 1e-08 35.2 9.3 2.5e-08 33.9 9.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RLN94964.1 - 1.7e-08 34.4 12.4 3.5e-08 33.4 12.4 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 RLN94964.1 - 7.7e-05 23.1 5.0 7.7e-05 23.1 5.0 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor SnoaL PF07366.12 RLN94964.1 - 0.0017 18.2 0.0 0.0034 17.2 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase GreA_GreB_N PF03449.15 RLN94964.1 - 0.0022 18.1 4.2 2.1 8.6 0.1 3.3 3 1 0 3 3 3 2 Transcription elongation factor, N-terminal SnoaL_2 PF12680.7 RLN94964.1 - 0.0099 16.5 0.0 0.023 15.3 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like domain TMCO5 PF14992.6 RLN94964.1 - 0.11 12.0 2.5 0.16 11.5 2.5 1.2 1 0 0 1 1 1 0 TMCO5 family RPAP2_Rtr1 PF04181.13 RLN94964.1 - 0.15 12.4 0.1 0.41 11.0 0.1 1.7 1 0 0 1 1 1 0 Rtr1/RPAP2 family Mt_ATP-synt_D PF05873.12 RLN94965.1 - 0.93 9.3 20.5 0.15 11.9 1.8 4.2 2 1 3 5 5 5 0 ATP synthase D chain, mitochondrial (ATP5H) DUF812 PF05667.11 RLN94965.1 - 3.4 6.4 22.2 4.5 6.0 22.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CorA PF01544.18 RLN94965.1 - 6 6.1 12.4 2.4 7.4 4.0 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF948 PF06103.11 RLN94965.1 - 6.1 7.2 13.9 1.8 8.8 2.4 3.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DivIVA PF05103.13 RLN94965.1 - 6.1 6.9 44.2 0.095 12.8 8.2 4.1 1 1 2 3 3 3 0 DivIVA protein DUF1284 PF06935.11 RLN94965.1 - 6.5 7.3 7.9 21 5.6 6.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1284) LRR_8 PF13855.6 RLN94966.1 - 6.6e-15 54.6 11.8 1.5e-07 31.0 0.7 3.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 RLN94966.1 - 1.4e-11 44.4 11.6 9.3e-06 25.9 0.8 3.0 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) Mid2 PF04478.12 RLN94966.1 - 0.00072 19.4 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Tweety PF04906.13 RLN94966.1 - 0.0023 16.7 0.2 0.0039 15.9 0.2 1.3 1 0 0 1 1 1 1 Tweety Adeno_E3_CR2 PF02439.15 RLN94966.1 - 0.0061 16.3 0.3 0.01 15.5 0.3 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 LRR_9 PF14580.6 RLN94966.1 - 0.011 15.2 1.4 0.024 14.1 1.4 1.4 1 1 0 1 1 1 0 Leucine-rich repeat stn_TNFRSF12A PF12191.8 RLN94966.1 - 0.013 15.7 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain TMEM154 PF15102.6 RLN94966.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Pkinase_Tyr PF07714.17 RLN94966.1 - 0.024 13.9 0.1 0.034 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Glycophorin_A PF01102.18 RLN94966.1 - 0.074 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A TNFR_16_TM PF18422.1 RLN94966.1 - 0.14 12.1 0.5 0.24 11.4 0.5 1.3 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain RasGEF PF00617.19 RLN94967.1 - 3.8e-25 89.1 0.0 6.4e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain AGA2 PF17366.2 RLN94968.1 - 0.0038 16.9 0.1 0.023 14.4 0.1 2.0 2 0 0 2 2 2 1 A-agglutinin-binding subunit Aga2 APC_basic PF05956.11 RLN94968.1 - 0.026 14.0 1.0 0.032 13.7 1.0 1.1 1 0 0 1 1 1 0 APC basic domain CENP-C_C PF11699.8 RLN94969.1 - 2.5e-07 30.8 0.0 0.00016 21.8 0.1 2.5 2 0 0 2 2 2 2 Mif2/CENP-C like Cupin_1 PF00190.22 RLN94969.1 - 0.012 15.3 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.11 RLN94969.1 - 0.056 13.2 0.1 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 Cupin domain HSF_DNA-bind PF00447.17 RLN94970.1 - 1.1e-17 64.4 1.0 1.3e-17 64.1 1.0 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding SLC12 PF03522.15 RLN94971.1 - 0.095 11.7 0.7 11 5.0 0.0 2.0 1 1 0 2 2 2 0 Solute carrier family 12 WD40 PF00400.32 RLN94972.1 - 8.6e-18 64.4 0.6 0.0012 19.6 0.0 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.8 RLN94972.1 - 1.5e-06 27.2 0.2 0.0096 14.6 0.0 3.1 3 0 0 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RLN94972.1 - 5.4e-05 22.3 0.4 0.045 12.7 0.0 3.0 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Aa_trans PF01490.18 RLN94973.1 - 1.5e-09 37.1 3.4 2e-09 36.7 3.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 RLN94973.1 - 0.028 13.5 1.6 0.037 13.1 1.6 1.1 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family PDZ PF00595.24 RLN94974.1 - 0.012 16.0 0.0 0.029 14.7 0.0 1.7 1 0 0 1 1 1 0 PDZ domain POTRA_TamA_1 PF17243.2 RLN94974.1 - 0.13 12.4 0.9 0.52 10.4 0.1 2.6 2 0 0 2 2 2 0 POTRA domain TamA domain 1 RapA_C PF12137.8 RLN94974.1 - 0.33 9.9 12.9 0.034 13.2 8.0 1.8 2 1 0 2 2 2 0 RNA polymerase recycling family C-terminal PDT PF00800.18 RLN94975.1 - 2.4e-39 135.0 0.1 6e-39 133.7 0.1 1.7 1 0 0 1 1 1 1 Prephenate dehydratase BrkDBD PF09607.10 RLN94975.1 - 7.8e-08 32.0 0.3 2.6e-07 30.3 0.4 1.9 2 0 0 2 2 2 1 Brinker DNA-binding domain CENP-B_N PF04218.13 RLN94975.1 - 2e-05 24.1 0.1 4.8e-05 22.9 0.1 1.6 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 RLN94975.1 - 0.00013 22.0 0.9 0.00039 20.5 0.9 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 RLN94975.1 - 0.00024 21.4 1.1 0.00024 21.4 1.1 2.0 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 RLN94975.1 - 0.01 15.6 0.5 0.026 14.3 0.5 1.6 1 0 0 1 1 1 0 Homeodomain-like domain ACT PF01842.25 RLN94975.1 - 0.056 13.2 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 ACT domain SNAP PF14938.6 RLN94977.1 - 1e-17 64.5 16.1 1.6e-17 63.8 16.1 1.2 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Glyco_hydro_1 PF00232.18 RLN94978.1 - 7.1e-123 410.4 0.7 8.5e-123 410.1 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 HIG_1_N PF04588.13 RLN94978.1 - 0.047 13.9 1.0 0.1 12.8 1.0 1.5 1 0 0 1 1 1 0 Hypoxia induced protein conserved region DAP10 PF07213.11 RLN94978.1 - 0.34 10.9 2.0 0.66 10.0 2.0 1.3 1 0 0 1 1 1 0 DAP10 membrane protein VSP PF03302.13 RLN94978.1 - 1.2 8.0 6.6 0.13 11.1 2.1 1.6 2 0 0 2 2 2 0 Giardia variant-specific surface protein Hydrolase PF00702.26 RLN94979.1 - 6.3e-45 154.1 0.6 1.2e-44 153.1 0.6 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RLN94979.1 - 9.9e-43 145.8 0.1 2.8e-42 144.3 0.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 RLN94979.1 - 2.1e-36 124.2 13.2 4.6e-09 36.6 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase_3 PF08282.12 RLN94979.1 - 1.1e-05 25.3 0.9 0.00075 19.3 0.6 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1700 PF08006.11 RLN94979.1 - 0.063 12.8 3.9 0.039 13.5 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) HAD PF12710.7 RLN94979.1 - 0.11 12.8 0.1 0.4 11.0 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase FeS_assembly_P PF01883.19 RLN94979.1 - 0.13 12.4 0.1 0.13 12.4 0.1 4.2 5 0 0 5 5 5 0 Iron-sulfur cluster assembly protein Fer2_BFD PF04324.15 RLN94979.1 - 2 8.8 7.9 20 5.6 0.0 4.1 4 0 0 4 4 4 0 BFD-like [2Fe-2S] binding domain DUF2997 PF11211.8 RLN94979.1 - 4.5 7.1 7.0 0.31 10.9 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2997) HECT PF00632.25 RLN94980.1 - 2e-52 178.6 0.0 2.2e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) NPR2 PF06218.11 RLN94981.1 - 1.8e-61 208.3 2.4 2.6e-43 148.4 3.0 4.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.13 RLN94981.1 - 0.059 12.2 0.1 0.14 10.9 0.1 1.5 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 PqqD PF05402.12 RLN94981.1 - 0.15 12.4 0.0 0.53 10.6 0.0 1.9 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) RAWUL PF16207.5 RLN94982.1 - 9.2e-05 23.0 0.1 0.00025 21.6 0.1 1.7 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like DUF3337 PF11816.8 RLN94982.1 - 0.012 15.5 0.1 0.032 14.1 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3337) IMPDH PF00478.25 RLN94983.1 - 5.2e-40 137.5 0.3 7e-40 137.1 0.3 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 RLN94983.1 - 1.2e-11 44.9 0.2 4.2e-07 30.3 0.0 2.7 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 RLN94983.1 - 0.00053 19.5 0.1 0.00091 18.7 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 RLN94984.1 - 3.7e-59 200.5 5.7 4.3e-59 200.2 5.7 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 RLN94984.1 - 1.4e-08 34.5 1.4 2e-08 34.0 1.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 RLN94984.1 - 3.9e-05 23.1 2.5 6.7e-05 22.3 2.2 1.5 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG FMN_dh PF01070.18 RLN94984.1 - 4.8e-05 22.6 2.5 8e-05 21.8 2.5 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DUF561 PF04481.12 RLN94984.1 - 0.00053 19.2 1.1 0.00077 18.7 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF561) His_biosynth PF00977.21 RLN94984.1 - 0.00059 19.4 2.1 0.31 10.5 0.2 2.2 1 1 1 2 2 2 2 Histidine biosynthesis protein NanE PF04131.14 RLN94984.1 - 0.019 14.1 0.9 0.43 9.7 0.1 2.2 1 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase DHO_dh PF01180.21 RLN94984.1 - 0.051 12.8 1.8 0.068 12.4 1.8 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 RLN94984.1 - 0.2 11.0 0.6 11 5.4 0.0 2.3 1 1 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator PWWP PF00855.17 RLN94988.1 - 1.4e-15 57.4 0.1 4.6e-15 55.8 0.1 2.0 1 0 0 1 1 1 1 PWWP domain JAB PF01398.21 RLN94988.1 - 3.4e-09 36.7 0.0 1.6e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 RLN94988.1 - 7.6e-07 28.9 0.0 2.4e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain TEX19 PF15553.6 RLN94988.1 - 9.6 6.1 11.9 15 5.5 1.4 4.0 3 0 0 3 3 3 0 Testis-expressed protein 19 Med26 PF08711.11 RLN94989.1 - 0.00057 19.9 0.0 0.0014 18.6 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Cupin_8 PF13621.6 RLN94990.1 - 0.053 13.2 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Cupin-like domain MR_MLE_N PF02746.16 RLN94991.1 - 0.0051 17.0 0.1 0.0067 16.6 0.1 1.1 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF3098 PF11297.8 RLN94991.1 - 0.078 12.6 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) Med11 PF10280.9 RLN94992.1 - 5.2e-06 27.0 0.1 6.6e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Mediator complex protein Hemerythrin PF01814.23 RLN94992.1 - 0.017 15.8 0.6 0.025 15.2 0.6 1.3 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain ArAE_2_N PF10337.9 RLN94992.1 - 0.066 12.2 0.1 0.077 12.0 0.1 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF5578 PF17741.1 RLN94993.1 - 0.00035 20.1 0.1 0.033 13.6 0.1 2.1 2 0 0 2 2 2 2 Family of unknown function (DUF5578) DUF913 PF06025.12 RLN94993.1 - 0.018 14.0 0.0 0.039 13.0 0.0 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) Tnp_22_trimer PF17489.2 RLN94993.1 - 0.064 13.2 0.8 0.19 11.7 0.8 1.8 1 0 0 1 1 1 0 L1 transposable element trimerization domain Cation_efflux PF01545.21 RLN94994.1 - 1.5e-25 90.1 14.9 1.9e-25 89.8 14.9 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 RLN94994.1 - 1.3e-11 44.5 0.2 2.4e-11 43.6 0.2 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF2583 PF10762.9 RLN94994.1 - 0.041 14.3 0.2 0.2 12.1 0.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) OrfB_Zn_ribbon PF07282.11 RLN94995.1 - 4.9e-09 36.0 0.5 1.4e-08 34.5 0.5 1.7 1 1 0 1 1 1 1 Putative transposase DNA-binding domain UPRTase PF14681.6 RLN94996.1 - 5.5e-23 81.5 0.2 9e-23 80.8 0.2 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PAXIP1_C PF15364.6 RLN94996.1 - 0.0012 19.2 0.0 0.0044 17.3 0.0 1.9 1 0 0 1 1 1 1 PAXIP1-associated-protein-1 C term PTIP binding protein HTH_7 PF02796.15 RLN94996.1 - 0.014 15.5 0.1 0.031 14.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase CENP-B_N PF04218.13 RLN94996.1 - 0.02 14.5 0.1 0.044 13.4 0.1 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain eIF3_N PF09440.10 RLN94997.1 - 2.1e-19 70.2 1.0 2.7e-19 69.9 1.0 1.1 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain DnaJ PF00226.31 RLN94998.1 - 9.9e-21 73.6 0.0 9.9e-21 73.6 0.0 2.3 3 0 0 3 3 3 1 DnaJ domain DnaI_N PF07319.11 RLN94998.1 - 0.38 11.4 2.6 0.54 11.0 1.4 1.9 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus adh_short PF00106.25 RLN94999.1 - 4.7e-32 111.0 3.0 6.3e-30 104.1 3.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN94999.1 - 1.9e-22 80.0 3.0 1.2e-10 41.3 0.2 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 RLN94999.1 - 3.5e-16 59.5 0.1 7.6e-16 58.4 0.1 1.6 1 0 0 1 1 1 1 SCP-2 sterol transfer family KR PF08659.10 RLN94999.1 - 3.3e-06 27.1 1.0 0.0053 16.7 0.2 2.3 2 0 0 2 2 2 2 KR domain Alkyl_sulf_C PF14864.6 RLN94999.1 - 0.025 14.9 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal AdoHcyase_NAD PF00670.21 RLN94999.1 - 0.11 12.5 0.5 0.24 11.4 0.5 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain SCP_3 PF17844.1 RLN94999.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial SCP ortholog CbiA PF01656.23 RLN94999.1 - 0.17 12.0 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Cyclin PF08613.11 RLN95000.1 - 1.2e-30 107.0 0.1 1.4e-30 106.8 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 RLN95000.1 - 7.4e-11 41.9 0.0 9.1e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Kri1_C PF12936.7 RLN95001.1 - 2.5e-26 91.7 4.7 2.5e-26 91.7 4.7 3.0 3 0 0 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.12 RLN95001.1 - 9.7e-22 77.5 9.8 9.7e-22 77.5 9.8 4.7 2 2 0 4 4 4 1 KRI1-like family PH_6 PF15406.6 RLN95001.1 - 0.64 10.3 5.7 0.28 11.5 1.4 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain cNMP_binding PF00027.29 RLN95002.1 - 3.8e-06 26.9 0.3 0.15 12.1 0.1 3.4 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Phage_int_SAM_4 PF13495.6 RLN95002.1 - 0.14 12.6 0.0 0.35 11.4 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain zf-CCHC_5 PF14787.6 RLN95002.1 - 0.24 11.2 0.5 1.3 8.8 0.3 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger FYVE PF01363.21 RLN95003.1 - 3.7e-17 62.2 10.9 7.1e-17 61.3 10.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF_2 PF13185.6 RLN95003.1 - 5.9e-07 29.9 0.0 3.7e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 RLN95003.1 - 0.0013 19.4 0.0 0.0058 17.2 0.0 2.2 2 0 0 2 2 2 1 GAF domain FYVE_2 PF02318.16 RLN95003.1 - 0.0018 18.4 6.6 0.0039 17.4 6.6 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger Transglut_prok PF09017.10 RLN95003.1 - 1.1 8.5 4.8 1.8 7.8 4.8 1.3 1 0 0 1 1 1 0 Microbial transglutaminase DUF4428 PF14471.6 RLN95003.1 - 1.2 9.2 7.7 11 6.1 2.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) Helicase_C_3 PF13625.6 RLN95004.1 - 6.9e-35 120.0 0.0 1.1e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sugar_tr PF00083.24 RLN95004.1 - 6.4e-06 25.3 1.2 9.6e-06 24.7 1.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter ResIII PF04851.15 RLN95004.1 - 0.00012 22.1 0.4 0.00064 19.8 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit EF-hand_7 PF13499.6 RLN95005.1 - 3.7e-21 75.3 2.1 4.5e-16 59.1 0.3 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN95005.1 - 1.3e-19 68.2 5.8 1.4e-08 33.6 0.9 3.8 4 0 0 4 4 4 3 EF hand C2 PF00168.30 RLN95005.1 - 2.7e-16 59.7 0.0 4.2e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 C2 domain EF-hand_6 PF13405.6 RLN95005.1 - 7.8e-16 56.6 0.3 0.0006 19.5 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 RLN95005.1 - 2e-13 49.1 3.0 1.7e-05 24.1 0.3 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RLN95005.1 - 2.4e-13 49.7 9.4 9.2e-09 35.0 0.5 3.8 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 RLN95005.1 - 0.00083 19.6 0.1 0.0029 17.9 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 RLN95005.1 - 0.0023 17.8 0.1 0.23 11.4 0.1 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RLN95005.1 - 0.051 13.9 0.0 0.41 11.0 0.0 2.0 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 RLN95005.1 - 0.11 12.6 0.2 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Ca2+ insensitive EF hand DUF1279 PF06916.13 RLN95007.1 - 4.9e-14 52.6 2.7 3.5e-13 49.9 2.7 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Kinesin PF00225.23 RLN95008.1 - 4.6e-51 173.7 3.5 8.2e-51 172.9 3.5 1.4 1 0 0 1 1 1 1 Kinesin motor domain ZZ PF00569.17 RLN95008.1 - 1.3e-08 34.5 1.9 1.3e-08 34.5 1.9 1.8 2 0 0 2 2 2 1 Zinc finger, ZZ type KLRAQ PF10205.9 RLN95008.1 - 0.068 13.4 1.4 0.28 11.4 1.4 2.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein bZIP_1 PF00170.21 RLN95008.1 - 0.1 12.7 1.9 0.44 10.7 1.9 2.2 1 0 0 1 1 1 0 bZIP transcription factor XhlA PF10779.9 RLN95008.1 - 0.1 12.8 0.5 0.38 11.0 0.5 1.9 1 0 0 1 1 1 0 Haemolysin XhlA Tropomyosin_1 PF12718.7 RLN95008.1 - 0.15 12.2 12.7 0.16 12.1 10.4 2.2 2 0 0 2 2 2 0 Tropomyosin like DUF4164 PF13747.6 RLN95008.1 - 0.25 11.6 6.2 0.21 11.9 3.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) BBP1_C PF15272.6 RLN95008.1 - 0.56 10.0 10.4 0.37 10.6 5.4 2.5 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal CENP-F_leu_zip PF10473.9 RLN95008.1 - 0.82 9.7 13.9 1 9.4 9.2 2.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tup_N PF08581.10 RLN95008.1 - 1.7 9.0 6.8 18 5.7 0.2 2.9 2 1 1 3 3 3 0 Tup N-terminal Ax_dynein_light PF10211.9 RLN95008.1 - 4.2 7.3 10.8 23 4.9 0.1 2.9 2 1 0 2 2 2 0 Axonemal dynein light chain Csm1_N PF18504.1 RLN95008.1 - 4.5 7.7 13.5 2.2 8.7 0.1 3.9 5 0 0 5 5 5 0 Csm1 N-terminal domain 2OG-FeII_Oxy_3 PF13640.6 RLN95009.1 - 1e-07 32.7 0.0 0.0021 18.9 0.0 2.5 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily zf-C3HC4_3 PF13920.6 RLN95011.1 - 9.4e-10 38.2 6.8 1.5e-09 37.6 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN95011.1 - 0.0079 16.5 7.0 0.015 15.6 7.0 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 RLN95011.1 - 0.0083 16.0 8.4 0.016 15.1 8.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Arm PF00514.23 RLN95012.1 - 6.3e-39 130.8 9.5 9.5e-06 25.5 0.0 6.6 7 1 0 7 7 7 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN95012.1 - 3.4e-16 59.4 9.9 0.00022 21.7 0.5 5.5 5 1 1 6 6 6 5 HEAT-like repeat HEAT PF02985.22 RLN95012.1 - 7.3e-16 56.9 4.0 0.74 10.2 0.0 6.3 6 0 0 6 6 6 5 HEAT repeat HEAT_2 PF13646.6 RLN95012.1 - 1.1e-09 38.5 20.8 6.1e-05 23.3 5.3 3.6 1 1 3 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 RLN95012.1 - 3.4e-05 24.1 23.8 10 7.2 0.2 6.6 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 RLN95012.1 - 4.1e-05 23.5 0.0 2.2 8.4 0.0 3.9 2 1 3 5 5 5 3 Spinocerebellar ataxia type 10 protein domain PGM_PMM_II PF02879.16 RLN95012.1 - 0.00038 21.0 9.7 32 5.2 0.0 5.7 6 0 0 6 6 6 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Tox-MPTase3 PF15639.6 RLN95012.1 - 0.00051 19.9 0.1 7.3 6.4 0.0 4.5 1 1 3 4 4 4 1 Metallopeptidase toxin 3 PfaD_N PF18328.1 RLN95012.1 - 0.00054 19.8 2.5 1.2e+02 2.7 0.0 5.7 6 0 0 6 6 6 0 Fatty acid synthase subunit PfaD N-terminal domain ATP-synt_F PF01990.17 RLN95012.1 - 0.025 14.9 3.7 46 4.4 0.2 4.7 2 1 2 4 4 4 0 ATP synthase (F/14-kDa) subunit NgoMIV_restric PF09015.10 RLN95012.1 - 0.025 13.7 1.8 10 5.1 0.1 3.3 1 1 4 5 5 5 0 NgoMIV restriction enzyme DUF294_C PF10335.9 RLN95012.1 - 0.027 14.2 4.0 4.4 7.1 0.0 4.5 2 2 4 6 6 6 0 Putative nucleotidyltransferase substrate binding domain Tex_N PF09371.10 RLN95012.1 - 0.061 13.0 4.7 32 4.1 0.0 4.3 1 1 4 5 5 5 0 Tex-like protein N-terminal domain YrzK PF17449.2 RLN95012.1 - 0.11 12.9 4.3 1.7e+02 2.6 0.0 4.4 5 0 0 5 5 4 0 Uncharacterized YrzK-like Succ_CoA_lig PF13607.6 RLN95012.1 - 0.11 12.3 7.1 52 3.6 0.1 4.9 1 1 4 6 6 6 0 Succinyl-CoA ligase like flavodoxin domain DUF3247 PF11607.8 RLN95012.1 - 0.16 12.3 0.7 1.3e+02 3.0 0.0 4.1 2 1 3 5 5 5 0 Protein of unknown function (DUF3247) UCR_14kD PF02271.16 RLN95012.1 - 0.26 11.3 9.0 87 3.2 0.1 4.8 5 0 0 5 5 5 0 Ubiquinol-cytochrome C reductase complex 14kD subunit GH97_C PF14509.6 RLN95012.1 - 0.75 10.1 7.0 1.1e+02 3.1 0.1 4.4 1 1 4 5 5 5 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation MFS_1 PF07690.16 RLN95013.1 - 3.1e-28 98.7 23.2 3.1e-28 98.7 23.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 RLN95013.1 - 0.81 8.9 22.3 0.21 10.9 6.8 2.1 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB PARP PF00644.20 RLN95014.1 - 1e-39 136.2 0.1 1.6e-34 119.2 0.0 2.9 3 1 0 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain Cation_ATPase_C PF00689.21 RLN95016.1 - 1.3e-49 168.4 3.0 1.3e-49 168.4 3.0 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 RLN95016.1 - 1.8e-31 109.0 11.8 5.8e-22 78.1 0.2 3.6 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase PF13246.6 RLN95016.1 - 7.1e-19 67.7 0.0 1.5e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RLN95016.1 - 4.4e-15 56.5 0.5 2e-14 54.4 0.5 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RLN95016.1 - 2.3e-12 46.4 0.0 9e-12 44.5 0.0 2.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RLN95016.1 - 5.3e-05 23.1 1.0 0.00073 19.4 0.7 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ATP_Ca_trans_C PF12424.8 RLN95016.1 - 0.0011 19.4 0.3 0.0025 18.2 0.3 1.7 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal DUF962 PF06127.11 RLN95016.1 - 0.11 12.6 0.4 1.9 8.6 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF962) NicO PF03824.16 RLN95016.1 - 0.3 10.4 8.0 0.056 12.8 0.6 2.5 2 0 0 2 2 2 0 High-affinity nickel-transport protein Strep_SA_rep PF06696.11 RLN95017.1 - 0.0027 17.6 0.6 0.12 12.4 0.0 2.6 2 0 0 2 2 2 1 Streptococcal surface antigen repeat APCDDC PF14921.6 RLN95017.1 - 0.18 11.2 0.1 0.3 10.5 0.1 1.2 1 0 0 1 1 1 0 Adenomatosis polyposis coli down-regulated 1 Cellulase PF00150.18 RLN95018.1 - 6.6e-11 42.2 0.0 1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF98 PF01947.16 RLN95019.1 - 4.6e-48 163.0 0.0 5.2e-48 162.8 0.0 1.0 1 0 0 1 1 1 1 p-hydroxybenzoic acid synthase RRM_1 PF00076.22 RLN95020.1 - 3.3e-20 71.7 0.0 6e-11 42.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RLN95020.1 - 3.1e-08 33.2 0.0 2.4e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RLN95020.1 - 9e-08 31.9 0.0 0.0014 18.4 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif tRNA-synt_1c PF00749.21 RLN95021.1 - 1.4e-96 323.1 0.0 2.5e-96 322.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 RLN95021.1 - 1.3e-33 116.3 0.0 3.1e-33 115.1 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Gal11_ABD1 PF18535.1 RLN95021.1 - 0.059 13.5 0.0 5.2 7.2 0.0 3.1 3 0 0 3 3 3 0 Gal11 activator-binding domain (ABD1) Ribosomal_L34 PF00468.17 RLN95022.1 - 6.1e-09 35.7 12.9 1.4e-08 34.5 12.9 1.6 1 0 0 1 1 1 1 Ribosomal protein L34 DUF4201 PF13870.6 RLN95023.1 - 0.0038 17.0 0.3 0.0049 16.6 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) PspA_IM30 PF04012.12 RLN95023.1 - 0.0054 16.3 0.3 0.0057 16.3 0.3 1.1 1 0 0 1 1 1 1 PspA/IM30 family CENP-F_leu_zip PF10473.9 RLN95023.1 - 0.01 15.8 0.1 0.012 15.7 0.1 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 RLN95023.1 - 0.017 14.7 0.6 0.019 14.6 0.6 1.0 1 0 0 1 1 1 0 Intermediate filament protein EzrA PF06160.12 RLN95023.1 - 0.032 12.4 0.2 0.036 12.3 0.2 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA CENP-K PF11802.8 RLN95023.1 - 0.085 12.4 0.6 0.096 12.2 0.6 1.1 1 0 0 1 1 1 0 Centromere-associated protein K HTH_37 PF13744.6 RLN95025.1 - 0.082 12.9 0.6 1.7 8.7 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain SET PF00856.28 RLN95025.1 - 0.11 12.9 1.0 2.1 8.7 0.0 2.8 2 2 1 3 3 3 0 SET domain MULE PF10551.9 RLN95026.1 - 4e-12 46.4 0.1 8.6e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain CBM_1 PF00734.18 RLN95027.1 - 1.9e-07 30.9 7.4 1.9e-07 30.9 7.4 3.7 3 1 0 3 3 3 2 Fungal cellulose binding domain NAD_Gly3P_dh_C PF07479.14 RLN95028.1 - 1e-23 84.2 0.0 1.2e-23 84.0 0.0 1.0 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 2OG-FeII_Oxy_3 PF13640.6 RLN95029.1 - 4.5e-18 65.9 0.0 7.4e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 RLN95029.1 - 1.6e-07 31.9 0.0 3.4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Phage_CI_C PF16452.5 RLN95030.1 - 5.2e-05 23.5 0.9 19 5.6 0.0 4.7 1 1 4 5 5 5 2 Bacteriophage CI repressor C-terminal domain PDR_CDR PF06422.12 RLN95030.1 - 0.12 12.3 0.0 27 4.8 0.0 2.9 1 1 2 3 3 3 0 CDR ABC transporter Coiled-coil_56 PF09813.9 RLN95030.1 - 0.49 10.5 3.2 52 4.0 0.1 3.5 1 1 4 5 5 5 0 Coiled-coil domain-containing protein 56 DUF1084 PF06454.11 RLN95031.1 - 0.0058 16.0 0.5 0.0058 16.0 0.5 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1084) SUR7 PF06687.12 RLN95031.1 - 2.9 7.5 11.8 0.88 9.2 2.9 2.3 2 0 0 2 2 2 0 SUR7/PalI family C2 PF00168.30 RLN95033.1 - 4.4e-20 71.9 0.0 6.1e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 C2 domain DJ-1_PfpI PF01965.24 RLN95034.1 - 6e-25 88.0 0.0 7.7e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 RLN95034.1 - 0.0092 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_5 PF13507.6 RLN95034.1 - 0.014 14.5 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain UPRTase PF14681.6 RLN95034.1 - 0.023 14.2 0.0 0.027 13.9 0.0 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Lig_chan PF00060.26 RLN95035.1 - 0.034 14.0 0.0 0.037 13.9 0.0 1.1 1 0 0 1 1 1 0 Ligand-gated ion channel DUF4381 PF14316.6 RLN95035.1 - 0.08 13.2 0.0 0.091 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) YWFCY PF14293.6 RLN95036.1 - 0.09 13.1 0.4 0.15 12.4 0.4 1.4 1 0 0 1 1 1 0 YWFCY protein DUF2678 PF10856.8 RLN95036.1 - 0.36 10.8 3.4 0.47 10.4 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) CAMSAP_CKK PF08683.11 RLN95037.1 - 1.2e-21 77.1 0.1 2.3e-21 76.2 0.1 1.4 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated KOG2701 PF09762.9 RLN95038.1 - 1.7e-37 129.4 0.0 1.7e-37 129.4 0.0 3.7 3 1 1 4 4 4 1 Coiled-coil domain-containing protein (DUF2037) Dimer_Tnp_hAT PF05699.14 RLN95039.1 - 1.8e-07 30.8 0.1 4.6e-07 29.5 0.1 1.7 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region WHEP-TRS PF00458.20 RLN95042.1 - 5e-16 58.6 4.0 5e-16 58.6 4.0 2.6 3 0 0 3 3 3 1 WHEP-TRS domain AP1AR PF15745.5 RLN95042.1 - 0.25 11.0 6.7 0.031 13.9 1.6 1.8 1 1 0 2 2 2 0 AP-1 complex-associated regulatory protein ACBP PF00887.19 RLN95043.1 - 7.9e-20 70.9 0.0 1.5e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein ALAD PF00490.21 RLN95044.1 - 1.3e-102 343.3 0.0 1.6e-102 343.0 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase PAPS_reduct PF01507.19 RLN95045.1 - 0.11 12.5 3.0 0.27 11.2 1.4 2.4 1 1 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family Baculo_PEP_C PF04513.12 RLN95045.1 - 1.3 9.1 23.7 0.45 10.5 0.1 4.6 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1515 PF07439.11 RLN95045.1 - 2.3 8.3 15.3 0.25 11.4 1.2 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF1515) Gp_dh_N PF00044.24 RLN95047.1 - 6.1e-19 68.2 0.0 1.8e-18 66.7 0.0 1.9 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain P34-Arc PF04045.14 RLN95047.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Arp2/3 complex, 34 kD subunit p34-Arc Caskin1-CID PF16600.5 RLN95048.1 - 0.99 10.0 6.5 6 7.5 6.5 2.4 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain DMRL_synthase PF00885.19 RLN95049.1 - 3.6e-57 192.1 2.4 4.6e-57 191.8 2.4 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Pkinase_Tyr PF07714.17 RLN95050.1 - 2.6e-44 151.5 0.0 1e-36 126.6 0.0 3.6 3 1 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 RLN95050.1 - 1.4e-39 136.1 0.0 1.1e-33 116.8 0.0 3.6 3 1 0 3 3 3 3 Protein kinase domain Pkinase_fungal PF17667.1 RLN95050.1 - 0.038 12.8 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 RLN95050.1 - 0.055 12.8 0.0 0.86 8.9 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Pkinase_Tyr PF07714.17 RLN95051.1 - 6.6e-44 150.1 0.0 3.7e-39 134.6 0.0 3.7 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 RLN95051.1 - 1.2e-42 146.1 0.0 1.5e-38 132.7 0.0 3.5 3 1 0 3 3 3 2 Protein kinase domain Pkinase_fungal PF17667.1 RLN95051.1 - 0.016 14.0 0.0 0.027 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 RLN95051.1 - 0.039 13.9 0.8 0.15 11.9 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family TPT PF03151.16 RLN95053.1 - 8.4e-28 97.5 17.1 1.2e-27 97.1 17.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family CH_2 PF06294.11 RLN95053.1 - 2.1e-14 53.4 0.2 9.1e-14 51.4 0.0 2.2 2 0 0 2 2 2 1 CH-like domain in sperm protein EamA PF00892.20 RLN95053.1 - 1.1e-05 25.6 11.0 1.1e-05 25.6 11.0 2.3 2 0 0 2 2 2 1 EamA-like transporter family UAA PF08449.11 RLN95053.1 - 0.001 18.3 10.6 0.002 17.4 10.5 1.5 1 1 0 1 1 1 1 UAA transporter family DUF2333 PF10095.9 RLN95054.1 - 0.028 13.4 0.6 0.049 12.6 0.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) DARPP-32 PF05395.12 RLN95055.1 - 0.04 14.2 5.0 0.048 13.9 5.0 1.1 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 NOA36 PF06524.12 RLN95055.1 - 0.092 12.1 19.0 0.096 12.0 19.0 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 RLN95055.1 - 0.14 10.2 18.4 0.14 10.3 18.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 RLN95055.1 - 0.44 9.9 13.7 0.51 9.7 13.7 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PPP4R2 PF09184.11 RLN95055.1 - 1.2 8.6 13.0 1.3 8.5 13.0 1.1 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 RLN95055.1 - 2.7 7.3 16.1 2.7 7.3 16.1 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RLN95055.1 - 5.1 5.2 17.1 5.2 5.2 17.1 1.0 1 0 0 1 1 1 0 Nop14-like family DnaJ PF00226.31 RLN95056.1 - 7.2e-25 86.9 3.9 1.1e-24 86.4 3.9 1.3 1 0 0 1 1 1 1 DnaJ domain DUF573 PF04504.14 RLN95056.1 - 0.031 14.9 0.1 0.053 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF573 BRE1 PF08647.11 RLN95057.1 - 6.9e-07 29.3 9.8 6.9e-07 29.3 9.8 9.0 4 2 6 10 10 10 2 BRE1 E3 ubiquitin ligase GAS PF13851.6 RLN95057.1 - 0.0034 16.8 10.4 0.0034 16.8 10.4 8.4 1 1 6 8 8 8 3 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 RLN95057.1 - 0.0054 17.0 18.6 0.0054 17.0 18.6 7.9 1 1 5 7 7 7 4 Autophagy protein 16 (ATG16) NOA36 PF06524.12 RLN95057.1 - 5.1 6.3 23.9 24 4.1 23.9 2.2 1 0 0 1 1 1 0 NOA36 protein PI_PP_I PF18363.1 RLN95057.1 - 9 6.6 10.5 4.4 7.6 0.9 4.7 3 2 2 5 5 5 0 Phosphoinositide phosphatase insertion domain adh_short PF00106.25 RLN95060.1 - 7.7e-41 139.7 0.1 1e-40 139.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN95060.1 - 2e-27 96.3 0.1 2.8e-27 95.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 RLN95060.1 - 0.00038 20.4 1.1 0.00069 19.5 0.1 1.9 2 1 0 2 2 2 1 NAD(P)H-binding DUF1776 PF08643.10 RLN95060.1 - 0.0024 17.3 0.0 0.0034 16.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Enterotoxin_HS1 PF08090.11 RLN95060.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Heat stable E.coli enterotoxin 1 adh_short PF00106.25 RLN95061.1 - 4e-44 150.4 0.2 5.3e-44 150.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN95061.1 - 1.1e-29 103.6 0.4 1.5e-29 103.2 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN95061.1 - 1.2e-06 28.6 0.2 1.7e-06 28.1 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 RLN95061.1 - 4.5e-05 23.4 2.2 7e-05 22.8 2.2 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Mce4_CUP1 PF11887.8 RLN95061.1 - 0.0022 17.5 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative ADH_zinc_N PF00107.26 RLN95061.1 - 0.0024 17.8 0.3 0.0065 16.4 0.3 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NmrA PF05368.13 RLN95061.1 - 0.0068 16.0 0.0 0.28 10.7 0.2 2.1 2 0 0 2 2 2 1 NmrA-like family DUF1776 PF08643.10 RLN95061.1 - 0.03 13.7 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 RLN95061.1 - 0.031 13.8 0.3 0.06 12.8 0.3 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Metallopep PF12044.8 RLN95062.1 - 3.1e-28 98.6 0.0 1.2e-27 96.7 0.0 1.8 1 1 0 1 1 1 1 Putative peptidase family OrfB_Zn_ribbon PF07282.11 RLN95062.1 - 0.53 10.3 3.3 2 8.4 3.3 2.0 1 1 0 1 1 1 0 Putative transposase DNA-binding domain EF-hand_1 PF00036.32 RLN95063.1 - 1.2e-20 71.5 2.1 1.6e-06 27.3 0.1 3.8 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 RLN95063.1 - 6.5e-19 67.5 3.5 7.3e-11 41.7 0.5 3.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RLN95063.1 - 5.4e-18 63.3 1.3 3.2e-05 23.5 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 RLN95063.1 - 6.6e-17 61.7 9.9 1.1e-10 41.8 1.0 3.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 RLN95063.1 - 2.7e-16 58.2 1.5 2e-05 23.9 0.2 3.7 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 RLN95063.1 - 2.8e-05 24.3 0.8 0.0022 18.3 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain Mlo PF03094.15 RLN95063.1 - 0.0002 19.9 7.2 0.026 12.9 0.4 2.1 1 1 0 2 2 2 2 Mlo family EF-hand_4 PF12763.7 RLN95063.1 - 0.0062 16.5 1.8 0.88 9.6 0.1 3.3 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand DUF996 PF06195.13 RLN95063.1 - 0.024 14.9 1.1 0.084 13.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF996) EF-hand_11 PF08976.11 RLN95063.1 - 0.031 15.2 0.2 2.7 8.9 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain DUF3349 PF11829.8 RLN95063.1 - 0.085 13.6 0.4 19 6.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) Trypsin_2 PF13365.6 RLN95064.1 - 5.7e-14 53.3 0.2 1.4e-13 52.0 0.2 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain ThiF PF00899.21 RLN95065.1 - 1.5e-23 83.4 0.0 3.3e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 ThiF family IQ PF00612.27 RLN95065.1 - 1e-09 37.3 59.4 0.062 13.1 0.5 8.4 8 0 0 8 8 8 7 IQ calmodulin-binding motif Peptidase_C1 PF00112.23 RLN95066.1 - 5e-57 193.5 3.0 7e-57 193.0 3.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RLN95066.1 - 0.0016 17.3 1.7 0.79 8.4 0.2 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Cu-oxidase_2 PF07731.14 RLN95067.1 - 2.5e-37 127.7 6.4 1.7e-29 102.3 0.2 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN95067.1 - 1.7e-32 111.9 3.7 1.1e-30 106.1 0.2 3.7 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 RLN95067.1 - 8.1e-24 84.5 0.0 2.4e-23 83.0 0.0 1.9 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 RLN95068.1 - 3.2e-38 130.6 2.6 5.8e-30 103.8 0.1 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN95068.1 - 1.1e-32 112.6 4.3 1.8e-31 108.6 0.2 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 RLN95068.1 - 1.6e-27 96.6 0.3 1e-26 93.9 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase adh_short PF00106.25 RLN95069.1 - 1.7e-44 151.6 1.9 2.3e-44 151.2 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN95069.1 - 9.3e-30 103.9 2.1 1.3e-29 103.5 2.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN95069.1 - 2.7e-07 30.7 2.1 4.1e-07 30.1 2.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 RLN95069.1 - 2.7e-06 27.0 0.0 3.7e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 RLN95069.1 - 0.085 12.3 0.2 0.13 11.7 0.2 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 RLN95069.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Cpta_toxin PF07254.12 RLN95070.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Membrane-bound toxin component of toxin-antitoxin system Macoilin PF09726.9 RLN95071.1 - 0.0028 16.3 22.4 0.0042 15.7 22.4 1.2 1 0 0 1 1 1 1 Macoilin family Dimer_Tnp_hAT PF05699.14 RLN95072.1 - 0.00014 21.6 0.0 0.00037 20.2 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 RLN95072.1 - 0.04 13.8 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) DUF1765 PF08578.10 RLN95073.1 - 1.2e-07 32.2 0.7 2.2e-07 31.4 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) SRR PF07709.11 RLN95073.1 - 1.5 9.6 4.2 18 6.3 2.2 2.9 2 0 0 2 2 2 0 Seven Residue Repeat RWP-RK PF02042.15 RLN95074.1 - 4.7e-18 64.9 0.1 9.3e-18 64.0 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain LRR_6 PF13516.6 RLN95075.1 - 2.2e-20 70.9 14.4 0.041 14.0 0.1 8.7 8 0 0 8 8 8 6 Leucine Rich repeat EF-hand_1 PF00036.32 RLN95075.1 - 1.3e-11 43.2 0.5 0.00011 21.5 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN95075.1 - 1.5e-09 37.0 0.5 0.00019 21.1 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RLN95075.1 - 2.6e-08 34.2 0.7 6.3e-08 33.0 0.7 1.7 1 0 0 1 1 1 1 EF-hand domain pair LRR_4 PF12799.7 RLN95075.1 - 0.0007 19.9 4.4 5.4 7.6 0.0 4.4 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) EF-hand_8 PF13833.6 RLN95075.1 - 0.0012 18.6 0.6 0.0044 16.8 0.3 2.2 1 1 1 2 2 2 1 EF-hand domain pair DUF4476 PF14771.6 RLN95075.1 - 0.0013 19.0 0.0 0.93 9.8 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4476) LRR_1 PF00560.33 RLN95075.1 - 0.0065 16.9 5.5 70 4.6 0.0 6.6 6 0 0 6 6 6 0 Leucine Rich Repeat EF-hand_5 PF13202.6 RLN95075.1 - 0.066 12.7 0.2 10 5.8 0.0 2.6 2 0 0 2 2 2 0 EF hand Haem_oxygenas_2 PF14518.6 RLN95075.1 - 0.12 12.2 0.4 0.55 10.0 0.0 2.4 2 1 0 2 2 2 0 Iron-containing redox enzyme LRR_8 PF13855.6 RLN95075.1 - 0.32 10.8 16.3 59 3.5 5.2 6.1 4 2 2 6 6 6 0 Leucine rich repeat MULE PF10551.9 RLN95076.1 - 4.1e-08 33.5 3.0 6.5e-08 32.9 0.4 2.6 2 0 0 2 2 2 1 MULE transposase domain FeS PF04060.13 RLN95077.1 - 0.2 11.4 3.5 3.3 7.4 0.2 2.4 2 0 0 2 2 2 0 Putative Fe-S cluster Pkinase PF00069.25 RLN95078.1 - 7.6e-23 81.2 0.0 9.8e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN95078.1 - 2.6e-22 79.4 0.0 3.5e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Transp_cyt_pur PF02133.15 RLN95079.1 - 2e-45 155.4 34.2 2.5e-45 155.0 34.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DER1 PF04511.15 RLN95080.1 - 0.00078 19.4 0.2 0.0014 18.6 0.2 1.5 1 1 0 1 1 1 1 Der1-like family Myosin_head PF00063.21 RLN95081.1 - 3.4e-154 514.7 0.0 8.7e-154 513.3 0.0 1.6 1 1 0 1 1 1 1 Myosin head (motor domain) Zeta_toxin PF06414.12 RLN95081.1 - 0.0051 16.1 0.5 0.012 14.9 0.5 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 RLN95081.1 - 0.0077 16.6 0.1 0.028 14.8 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RLN95081.1 - 0.011 16.0 0.8 0.038 14.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Myosin_N PF02736.19 RLN95081.1 - 0.013 15.3 0.1 0.024 14.4 0.1 1.4 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain RNA_helicase PF00910.22 RLN95081.1 - 0.037 14.4 0.1 0.081 13.3 0.1 1.6 1 0 0 1 1 1 0 RNA helicase OST3_OST6 PF04756.13 RLN95082.1 - 0.24 10.7 0.2 0.34 10.2 0.2 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF4589 PF15252.6 RLN95082.1 - 6.4 6.7 9.0 2.3 8.2 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4589) Linker_histone PF00538.19 RLN95083.1 - 1.1e-19 70.5 0.2 1.1e-19 70.5 0.2 2.2 2 1 0 2 2 2 1 linker histone H1 and H5 family MULE PF10551.9 RLN95084.1 - 4e-08 33.6 0.3 1.3e-07 31.9 0.3 1.8 2 0 0 2 2 2 1 MULE transposase domain Methyltransf_16 PF10294.9 RLN95085.1 - 9.6e-25 87.3 0.0 1.3e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 RLN95085.1 - 0.035 14.8 0.0 0.081 13.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 RLN95085.1 - 0.049 14.4 0.0 0.15 12.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 RLN95085.1 - 0.054 13.0 0.1 0.095 12.2 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF938 PF06080.12 RLN95085.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Cons_hypoth95 PF03602.15 RLN95085.1 - 0.16 11.6 0.0 0.49 10.0 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Sugar_tr PF00083.24 RLN95086.1 - 3.8e-104 349.1 25.9 4.3e-104 348.9 25.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN95086.1 - 3.7e-27 95.2 29.3 2e-21 76.3 6.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily CbtA PF09490.10 RLN95086.1 - 0.0073 16.1 0.5 0.0073 16.1 0.5 2.5 3 0 0 3 3 3 1 Probable cobalt transporter subunit (CbtA) EMP70 PF02990.16 RLN95087.1 - 6.3e-153 510.2 4.0 8.5e-153 509.7 4.0 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 CorA PF01544.18 RLN95087.1 - 0.47 9.7 4.8 0.12 11.7 0.6 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DnaJ PF00226.31 RLN95088.1 - 2.9e-39 133.0 1.3 3.1e-18 65.7 0.1 3.0 2 0 0 2 2 2 2 DnaJ domain Lipase_3 PF01764.25 RLN95088.1 - 4.9e-13 49.2 0.2 0.086 12.7 0.0 5.4 6 0 0 6 6 5 3 Lipase (class 3) Hydrolase_4 PF12146.8 RLN95088.1 - 1.2e-05 24.7 0.1 0.19 10.9 0.0 3.1 3 0 0 3 3 3 2 Serine aminopeptidase, S33 DUF2974 PF11187.8 RLN95088.1 - 5e-05 23.0 0.0 0.3 10.6 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) PGAP1 PF07819.13 RLN95088.1 - 7.3e-05 22.6 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 PGAP1-like protein EF-hand_1 PF00036.32 RLN95088.1 - 0.0011 18.4 0.0 0.26 10.9 0.0 2.8 2 0 0 2 2 2 1 EF hand SNARE_assoc PF09335.11 RLN95088.1 - 0.0031 18.0 6.3 0.33 11.4 1.3 2.9 2 0 0 2 2 2 2 SNARE associated Golgi protein EF-hand_6 PF13405.6 RLN95088.1 - 0.0041 16.9 0.0 4.8 7.4 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RLN95088.1 - 0.0067 16.9 0.6 4.5 7.8 0.0 4.0 4 0 0 4 4 4 1 EF-hand domain pair GPHH PF16905.5 RLN95088.1 - 0.028 14.2 0.0 2 8.3 0.0 2.8 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_8 PF13833.6 RLN95088.1 - 0.093 12.6 0.0 0.35 10.7 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain pair LIDHydrolase PF10230.9 RLN95088.1 - 0.15 11.6 0.0 19 4.7 0.0 3.0 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase LapA_dom PF06305.11 RLN95088.1 - 0.63 9.9 3.9 20 5.1 0.1 3.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF3164 PF11363.8 RLN95088.1 - 0.72 9.4 3.6 0.98 9.0 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3164) Phage_holin_3_6 PF07332.11 RLN95088.1 - 0.93 9.6 27.6 0.016 15.3 2.7 4.2 5 0 0 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III WD40 PF00400.32 RLN95089.1 - 2.2e-66 218.1 17.0 8.6e-08 32.7 0.1 11.2 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 RLN95089.1 - 1.3e-39 135.3 0.0 2.1e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 RLN95089.1 - 4.9e-16 58.8 4.4 0.00021 21.5 0.0 7.8 4 3 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN95089.1 - 6.9e-11 41.7 6.4 0.17 10.8 0.0 7.1 3 3 5 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RLN95089.1 - 1.7e-06 27.0 7.8 0.082 11.5 0.0 5.9 5 3 2 7 7 7 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 RLN95089.1 - 2.3e-05 23.1 0.4 0.02 13.4 0.1 3.7 3 1 2 5 5 5 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 RLN95089.1 - 0.00036 19.4 0.0 8 5.1 0.0 4.4 2 1 1 4 4 4 2 Nup133 N terminal like VID27 PF08553.10 RLN95089.1 - 0.012 14.7 0.0 0.04 13.0 0.0 1.8 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain DUF1513 PF07433.11 RLN95089.1 - 0.037 13.1 1.5 2.5 7.1 0.0 3.6 2 2 2 5 5 5 0 Protein of unknown function (DUF1513) WD40_like PF17005.5 RLN95089.1 - 0.067 12.5 0.0 2.1 7.6 0.0 2.8 3 0 0 3 3 3 0 WD40-like domain nos_propeller PF18764.1 RLN95089.1 - 0.088 12.7 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Nitrous oxide reductase propeller repeat FISNA PF14484.6 RLN95090.1 - 0.063 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Fish-specific NACHT associated domain DUF727 PF05303.12 RLN95090.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF727) Globin PF00042.22 RLN95091.1 - 0.00081 19.9 0.1 0.0039 17.7 0.1 2.1 1 1 0 1 1 1 1 Globin Ank_4 PF13637.6 RLN95092.1 - 9.2e-28 96.3 0.2 5.1e-10 39.7 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN95092.1 - 1.6e-22 79.9 0.1 1.3e-14 54.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RLN95092.1 - 7.1e-21 73.7 2.2 2.7e-06 27.6 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 RLN95092.1 - 1.7e-19 67.8 1.2 3e-05 24.1 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 RLN95092.1 - 1.8e-18 66.3 0.8 1.3e-06 28.5 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF2431 PF10354.9 RLN95093.1 - 2e-44 151.8 0.0 2.5e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) COE1_DBD PF16422.5 RLN95093.1 - 0.021 14.2 0.3 0.039 13.4 0.0 1.5 2 0 0 2 2 2 0 Transcription factor COE1 DNA-binding domain MTS PF05175.14 RLN95093.1 - 0.18 11.3 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain zf-C3HC4_3 PF13920.6 RLN95094.1 - 1.5e-09 37.6 9.9 1.5e-09 37.6 9.9 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN95094.1 - 4e-09 36.2 10.6 9.1e-09 35.0 10.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN95094.1 - 1.1e-07 31.6 7.9 2.3e-07 30.6 7.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN95094.1 - 8.2e-07 28.9 11.9 8.2e-07 28.9 11.9 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RLN95094.1 - 1.4e-06 28.0 11.5 1.4e-06 28.0 11.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN95094.1 - 2e-06 28.0 10.2 4.9e-06 26.8 10.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.6 RLN95094.1 - 2.7e-05 23.9 2.7 5.3e-05 23.0 2.7 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 RLN95094.1 - 0.00071 19.8 6.5 0.0023 18.2 6.5 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RLN95094.1 - 0.0028 17.6 9.1 0.0066 16.5 9.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 RLN95094.1 - 0.067 13.0 8.4 0.18 11.6 8.4 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 RLN95094.1 - 0.16 11.9 7.1 0.35 10.8 7.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RLN95094.1 - 0.48 10.5 4.0 1.1 9.4 4.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger A2L_zn_ribbon PF08792.10 RLN95094.1 - 0.52 10.1 6.5 1.7 8.4 6.5 1.9 1 0 0 1 1 1 0 A2L zinc ribbon domain zf-C3HC4_4 PF15227.6 RLN95094.1 - 0.54 10.5 7.6 1.5 9.0 7.6 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Med9 PF07544.13 RLN95094.1 - 0.92 9.6 31.7 0.31 11.1 2.1 6.6 4 2 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 HALZ PF02183.18 RLN95094.1 - 4.1 7.7 16.8 2 8.7 0.1 5.7 5 1 1 6 6 6 0 Homeobox associated leucine zipper zf-UDP PF14569.6 RLN95094.1 - 6.2 7.0 12.1 0.25 11.5 4.8 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger TauE PF01925.19 RLN95095.1 - 4.5e-06 26.5 1.5 5.5e-06 26.2 1.5 1.1 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF1772 PF08592.11 RLN95095.1 - 0.02 15.2 0.4 0.22 11.9 0.3 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) TauE PF01925.19 RLN95096.1 - 1.7e-11 44.3 15.6 1.7e-11 44.3 15.6 2.7 1 1 0 2 2 2 1 Sulfite exporter TauE/SafE COX16 PF14138.6 RLN95096.1 - 0.8 10.3 2.1 0.93 10.0 0.0 2.2 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein COX16 Abhydrolase_3 PF07859.13 RLN95099.1 - 7.8e-23 81.4 0.0 1.2e-22 80.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 RLN95099.1 - 9.8e-07 28.0 0.0 5e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 RLN95099.1 - 5.3e-05 22.8 0.1 0.025 14.1 0.0 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family DUF2974 PF11187.8 RLN95099.1 - 0.0086 15.6 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Say1_Mug180 PF10340.9 RLN95099.1 - 0.039 12.8 0.0 0.063 12.1 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 RLN95100.1 - 6e-25 88.3 0.0 9.5e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN95100.1 - 5.1e-09 35.9 2.0 4.1e-08 33.0 0.7 2.5 2 1 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.28 RLN95100.1 - 2.2e-08 33.5 0.0 5e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 RLN95100.1 - 0.072 13.7 4.7 0.087 13.4 2.7 2.1 2 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 RLN95101.1 - 1.4e-22 80.6 0.0 2e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN95101.1 - 4.8e-06 26.2 0.0 8.7e-05 22.1 0.0 2.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 RLN95101.1 - 1.5e-05 24.1 0.1 0.00012 21.2 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 RLN95101.1 - 0.0013 18.1 0.1 0.11 11.7 0.0 2.4 2 1 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 RLN95101.1 - 0.11 12.2 0.0 0.74 9.4 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 RLN95102.1 - 2e-25 89.9 0.0 2.8e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RLN95102.1 - 3.5e-06 26.6 0.1 7.2e-05 22.4 0.1 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 RLN95102.1 - 6.9e-06 25.2 0.0 3.4e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 RLN95102.1 - 0.0076 15.1 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF2974 PF11187.8 RLN95102.1 - 0.019 14.6 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 RLN95102.1 - 0.049 12.9 0.0 1.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Rad17 PF03215.15 RLN95103.1 - 1.1e-16 61.3 0.0 3.6e-16 59.6 0.0 1.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 RLN95103.1 - 0.00026 21.2 0.1 0.0012 19.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN95103.1 - 0.00045 20.6 0.1 0.0026 18.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain zf-RanBP PF00641.18 RLN95103.1 - 0.00046 19.4 1.6 0.0011 18.2 1.6 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others AAA_22 PF13401.6 RLN95103.1 - 0.0015 18.8 0.0 0.0041 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 RLN95103.1 - 0.0023 18.3 0.0 0.0063 16.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RLN95103.1 - 0.0024 18.4 0.0 0.0077 16.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.27 RLN95103.1 - 0.01 16.3 0.0 0.11 13.0 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_assoc_2 PF16193.5 RLN95103.1 - 0.019 15.3 0.0 0.055 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain RNA_helicase PF00910.22 RLN95103.1 - 0.02 15.3 0.0 0.065 13.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 RLN95103.1 - 0.063 13.2 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_17 PF13207.6 RLN95103.1 - 0.098 13.1 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RLN95103.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 RLN95103.1 - 0.13 12.2 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 RLN95103.1 - 0.14 12.1 0.0 0.39 10.6 0.0 1.8 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 DUF3678 PF12435.8 RLN95103.1 - 0.43 10.0 5.5 1.1 8.7 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Sugar_tr PF00083.24 RLN95104.1 - 7e-100 335.0 27.8 8e-100 334.8 27.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN95104.1 - 8.7e-27 94.0 32.0 3.4e-22 78.8 9.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily CbtA PF09490.10 RLN95104.1 - 0.01 15.6 0.3 0.01 15.6 0.3 2.5 2 1 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) Abhydrolase_9_N PF15420.6 RLN95104.1 - 0.1 12.6 0.0 0.1 12.6 0.0 3.0 4 0 0 4 4 4 0 Alpha/beta-hydrolase family N-terminus Methyltransf_16 PF10294.9 RLN95105.1 - 3.8e-29 101.6 0.0 6.9e-29 100.8 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 RLN95105.1 - 4.6e-05 23.3 0.0 6.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN95105.1 - 0.0022 17.5 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MethyltransfD12 PF02086.15 RLN95105.1 - 0.043 13.5 0.0 1.7 8.3 0.0 2.1 1 1 1 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_12 PF08242.12 RLN95105.1 - 0.088 13.6 0.0 0.49 11.2 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 RLN95105.1 - 0.15 11.3 0.0 0.32 10.3 0.0 1.6 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G DUF3611 PF12263.8 RLN95105.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) CHAT PF12770.7 RLN95106.1 - 1.2e-09 38.0 0.0 6e-09 35.7 0.0 2.0 1 1 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 RLN95106.1 - 4.1e-09 36.6 1.0 1.8e-07 31.3 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_16 PF13191.6 RLN95106.1 - 6.7e-08 33.1 1.1 3.7e-07 30.7 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain TPR_2 PF07719.17 RLN95106.1 - 7.9e-06 25.6 0.8 0.011 15.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat NACHT PF05729.12 RLN95106.1 - 1.3e-05 25.2 0.0 2.7e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 RLN95106.1 - 0.00037 20.8 0.1 0.0013 19.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain TPR_10 PF13374.6 RLN95106.1 - 0.005 16.7 0.5 0.081 12.8 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_25 PF13481.6 RLN95106.1 - 0.012 15.2 0.0 0.039 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_1 PF00515.28 RLN95106.1 - 0.021 14.6 0.3 0.23 11.3 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat NTPase_1 PF03266.15 RLN95106.1 - 0.11 12.3 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.14 RLN95106.1 - 0.15 12.0 0.0 0.55 10.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 RLN95106.1 - 0.16 11.1 0.0 0.35 10.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain K_channel_TID PF07941.11 RLN95106.1 - 0.88 10.1 6.0 0.37 11.3 2.1 2.5 1 1 1 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Leuk-A4-hydro_C PF09127.11 RLN95107.1 - 4e-20 72.0 0.1 6.4e-20 71.3 0.1 1.3 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1 PF01433.20 RLN95107.1 - 8e-05 22.3 0.0 0.015 14.9 0.0 2.3 2 0 0 2 2 2 2 Peptidase family M1 domain Peptidase_M1_N PF17900.1 RLN95108.1 - 7.2e-18 65.4 0.0 1.2e-17 64.8 0.0 1.4 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 RLN95108.1 - 1.8e-07 30.9 0.0 2.9e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain NHL PF01436.21 RLN95109.1 - 3.3e-21 74.2 27.9 1.1e-05 25.2 0.8 10.4 11 1 0 11 11 11 6 NHL repeat DUF5128 PF17170.4 RLN95109.1 - 7.2e-06 25.4 0.0 0.021 14.0 0.0 3.2 3 0 0 3 3 3 2 6-bladed beta-propeller DUF5401 PF17380.2 RLN95109.1 - 2.6 6.0 15.0 3.9 5.4 15.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF1682 PF07946.14 RLN95109.1 - 5.9 6.0 10.1 9.5 5.3 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PALP PF00291.25 RLN95110.1 - 3.5e-24 85.8 0.0 5.5e-15 55.6 0.0 2.1 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme Pro-kuma_activ PF09286.11 RLN95111.1 - 5.1e-19 69.0 0.0 1e-18 68.0 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 RLN95111.1 - 0.042 13.1 0.1 0.08 12.2 0.1 1.4 1 0 0 1 1 1 0 Subtilase family Claudin_3 PF06653.11 RLN95111.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Tight junction protein, Claudin-like DAO PF01266.24 RLN95113.1 - 9.2e-46 157.0 0.0 1.1e-45 156.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF1115 PF06544.12 RLN95114.1 - 3.1e-11 43.6 0.0 4.8e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Lipoxygenase PF00305.19 RLN95114.1 - 0.11 10.9 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Lipoxygenase Sugar_tr PF00083.24 RLN95115.1 - 5.7e-31 107.9 7.9 6.7e-31 107.6 7.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Ank_3 PF13606.6 RLN95116.1 - 3.4e-19 66.9 0.9 0.035 14.6 0.0 6.5 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.7 RLN95116.1 - 4.1e-18 65.8 3.5 4.4e-06 27.2 1.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN95116.1 - 1.5e-17 63.7 1.2 0.00032 21.2 0.0 5.6 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN95116.1 - 5.1e-16 58.3 4.1 0.12 12.8 0.0 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 RLN95116.1 - 4.4e-12 46.0 2.5 0.0017 18.6 0.1 5.1 4 1 1 5 5 5 2 Ankyrin repeats (many copies) OmdA PF13376.6 RLN95116.1 - 0.2 11.7 0.7 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated DAGAT PF03982.13 RLN95117.1 - 3e-43 147.9 0.5 4.5e-43 147.3 0.5 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Ras PF00071.22 RLN95118.1 - 5.2e-20 71.7 0.1 6.2e-18 64.9 0.0 2.8 2 1 0 2 2 2 1 Ras family Roc PF08477.13 RLN95118.1 - 1.6e-10 41.2 0.0 6.4e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase EF_assoc_2 PF08356.12 RLN95118.1 - 1.8e-10 40.7 0.0 4.3e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 RLN95118.1 - 3.8e-07 29.6 0.0 1.7e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 EF hand associated EF-hand_6 PF13405.6 RLN95118.1 - 6e-06 25.8 0.2 0.19 11.8 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RLN95118.1 - 1.6e-05 25.3 0.5 0.48 10.9 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN95118.1 - 1.7e-05 24.0 0.3 0.19 11.4 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 RLN95118.1 - 6.3e-05 22.3 0.2 0.54 9.8 0.0 2.6 2 0 0 2 2 2 2 EF hand Arf PF00025.21 RLN95118.1 - 0.00014 21.4 0.1 0.00046 19.7 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RLN95118.1 - 0.0011 19.1 0.0 0.0059 16.7 0.0 2.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RLN95118.1 - 0.018 14.6 0.2 0.09 12.3 0.1 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 RLN95118.1 - 0.062 13.2 0.1 1.2 9.0 0.0 2.6 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 RLN95118.1 - 0.12 12.1 0.0 5 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 RLN95118.1 - 0.13 12.1 0.1 2.6 7.9 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase RabGAP-TBC PF00566.18 RLN95119.1 - 2.4e-36 125.4 0.5 3.4e-36 124.9 0.5 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_5 PF13857.6 RLN95119.1 - 5.2e-10 39.4 0.5 6.1e-07 29.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN95119.1 - 3.8e-08 33.7 0.2 8.3e-08 32.6 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN95119.1 - 6.9e-07 29.8 0.0 1.7e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN95119.1 - 2.8e-05 24.1 0.3 0.078 13.6 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 RLN95119.1 - 0.00012 22.4 0.2 0.0085 16.5 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Shisa PF13908.6 RLN95119.1 - 0.0031 17.8 1.3 0.0088 16.3 1.3 1.7 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator PDEase_I PF00233.19 RLN95120.1 - 4.7e-65 219.6 0.1 1.2e-64 218.3 0.1 1.7 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF_2 PF13185.6 RLN95120.1 - 1e-08 35.6 0.0 5e-06 26.9 0.0 2.7 2 0 0 2 2 2 2 GAF domain GAF PF01590.26 RLN95120.1 - 5.3e-06 27.1 0.5 0.029 15.0 0.1 2.9 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 RLN95120.1 - 0.00046 20.5 0.1 0.14 12.5 0.0 2.9 2 0 0 2 2 2 2 GAF domain HD PF01966.22 RLN95120.1 - 0.019 15.2 0.6 0.052 13.8 0.6 1.8 1 1 0 1 1 1 0 HD domain Tim17 PF02466.19 RLN95121.1 - 1.2e-06 28.8 0.8 2.1e-06 28.1 0.8 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DnaJ PF00226.31 RLN95122.1 - 7.1e-05 22.8 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain TraP PF07296.11 RLN95122.1 - 0.095 11.9 0.1 0.24 10.6 0.1 1.6 1 0 0 1 1 1 0 TraP protein Pkinase PF00069.25 RLN95123.1 - 1.5e-49 168.8 0.0 4.5e-47 160.6 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN95123.1 - 4.6e-15 55.6 0.0 6.2e-13 48.6 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase PRK PF00485.18 RLN95123.1 - 0.1 12.3 0.0 2.3 7.9 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ubiquitin PF00240.23 RLN95124.1 - 2.9e-06 26.9 0.0 5.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RLN95124.1 - 0.0029 17.4 0.0 0.005 16.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IspA PF04279.15 RLN95124.1 - 0.0077 16.4 0.2 0.013 15.7 0.2 1.3 1 0 0 1 1 1 1 Intracellular septation protein A Rad60-SLD_2 PF13881.6 RLN95124.1 - 0.043 13.9 0.0 1 9.5 0.0 2.3 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CBS PF00571.28 RLN95125.1 - 2.9e-26 91.7 2.3 3.9e-07 30.4 0.0 4.8 4 1 1 5 5 5 4 CBS domain GAF PF01590.26 RLN95125.1 - 0.004 17.8 0.1 0.14 12.8 0.0 2.5 1 1 0 2 2 2 1 GAF domain Presenilin PF01080.17 RLN95126.1 - 4.2e-61 206.9 6.2 4.2e-61 206.9 6.2 2.9 2 1 0 2 2 2 1 Presenilin Baculo_LEF-11 PF06385.12 RLN95128.1 - 0.054 14.0 2.4 0.07 13.6 2.4 1.1 1 0 0 1 1 1 0 Baculovirus LEF-11 protein DUF4047 PF13256.6 RLN95128.1 - 0.059 13.6 4.9 0.1 12.8 4.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) Cep57_CLD_2 PF14197.6 RLN95128.1 - 0.069 13.3 3.3 0.71 10.0 0.1 2.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Pro-rich_19 PF15455.6 RLN95128.1 - 0.12 11.5 0.1 0.13 11.4 0.1 1.1 1 0 0 1 1 1 0 Proline-rich 19 PKcGMP_CC PF16808.5 RLN95128.1 - 0.51 10.2 0.2 0.51 10.2 0.2 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Enkurin PF13864.6 RLN95128.1 - 0.91 10.0 9.5 1.2 9.6 0.7 2.0 1 1 1 2 2 2 0 Calmodulin-binding NOT2_3_5 PF04153.18 RLN95129.1 - 3.7e-22 78.8 4.4 1.7e-21 76.6 4.4 1.9 1 1 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Pkinase_Tyr PF07714.17 RLN95130.1 - 4.3e-23 81.9 0.0 5.6e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN95130.1 - 3.3e-21 75.8 0.0 5e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DZR PF12773.7 RLN95130.1 - 0.00013 21.9 1.7 0.00024 21.0 1.7 1.5 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 RLN95130.1 - 0.0061 17.3 1.1 0.011 16.4 1.1 1.5 1 0 0 1 1 1 1 zinc-ribbon family Kinase-like PF14531.6 RLN95130.1 - 0.015 14.6 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like EccE PF11203.8 RLN95130.1 - 0.04 14.2 2.2 0.079 13.3 2.2 1.4 1 0 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE zf-ribbon_3 PF13248.6 RLN95130.1 - 0.18 11.2 5.2 0.45 10.0 5.2 1.7 1 0 0 1 1 1 0 zinc-ribbon domain CNDH2_C PF16858.5 RLN95131.1 - 2.3e-07 31.0 0.4 2.8e-07 30.7 0.4 1.3 1 1 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term Get5_bdg PF16843.5 RLN95131.1 - 0.081 12.4 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein DnaB_bind PF10410.9 RLN95131.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase Mobilization_B PF17511.2 RLN95135.1 - 0.049 14.0 0.8 0.071 13.5 0.8 1.2 1 0 0 1 1 1 0 Mobilization protein B IQ PF00612.27 RLN95136.1 - 4e-06 26.1 85.2 0.0034 17.1 3.6 10.1 9 0 0 9 9 9 6 IQ calmodulin-binding motif LRR_6 PF13516.6 RLN95136.1 - 0.004 17.1 0.1 14 6.1 0.0 3.6 3 0 0 3 3 3 1 Leucine Rich repeat EF-hand_6 PF13405.6 RLN95136.1 - 0.077 13.0 0.2 0.2 11.7 0.2 1.7 1 0 0 1 1 1 0 EF-hand domain Peptidase_S10 PF00450.22 RLN95138.1 - 1.2e-109 367.5 0.0 1.5e-109 367.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase adh_short PF00106.25 RLN95139.1 - 1.7e-33 115.8 0.2 1.7e-29 102.7 0.1 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN95139.1 - 8.7e-20 71.3 0.1 1.7e-19 70.3 0.1 1.4 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN95139.1 - 7.7e-10 39.0 0.1 1.1e-09 38.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Pyr_redox_3 PF13738.6 RLN95139.1 - 0.00095 18.5 0.0 0.0013 18.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 RLN95139.1 - 0.0021 17.5 0.1 0.0029 17.1 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RLN95139.1 - 0.069 12.5 0.1 0.089 12.2 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Clusterin PF01093.17 RLN95140.1 - 0.0072 15.4 1.2 0.4 9.7 0.1 2.2 2 0 0 2 2 2 2 Clusterin UPF0184 PF03670.13 RLN95140.1 - 3 8.3 6.2 2.9 8.3 0.4 3.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) UPF0242 PF06785.11 RLN95140.1 - 4.4 7.4 19.7 2.7 8.0 8.8 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 RLN95140.1 - 4.6 5.0 15.8 0.18 9.7 4.6 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 RLN95140.1 - 6.1 7.4 33.6 0.12 12.9 9.9 2.8 2 0 0 2 2 2 0 Apg6 coiled-coil region Spc29 PF17082.5 RLN95140.1 - 7.7 6.3 12.2 0.96 9.2 5.7 2.7 2 2 0 2 2 2 0 Spindle Pole Component 29 Patched PF02460.18 RLN95141.1 - 1.1e-29 103.1 12.1 7.8e-22 77.2 1.0 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 RLN95141.1 - 9.8e-26 90.4 15.5 1.4e-25 89.9 6.9 3.8 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation NPC1_N PF16414.5 RLN95141.1 - 1.3e-17 64.2 12.5 2.7e-17 63.2 12.5 1.4 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus DUF1180 PF06679.12 RLN95141.1 - 0.66 10.4 2.0 1.1 9.6 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) OST3_OST6 PF04756.13 RLN95141.1 - 9.4 5.5 5.7 5.1 6.4 0.1 2.5 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family A_deaminase PF00962.22 RLN95142.1 - 2.5e-54 184.8 0.2 2.5e-30 106.0 0.3 2.1 2 0 0 2 2 2 2 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 RLN95142.1 - 0.014 14.7 0.8 0.08 12.2 0.8 2.1 2 0 0 2 2 2 0 Amidohydrolase family zf-HC5HC2H_2 PF13832.6 RLN95143.1 - 7.1e-22 77.7 7.9 1.4e-20 73.5 0.8 3.0 2 1 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RLN95143.1 - 1.9e-20 72.9 9.5 2.3e-19 69.4 0.0 3.1 3 0 0 3 3 3 2 PHD-like zinc-binding domain PHD PF00628.29 RLN95143.1 - 3.6e-07 30.0 21.3 1.1e-05 25.3 5.7 3.3 4 0 0 4 4 4 2 PHD-finger zf-RING-like PF08746.11 RLN95143.1 - 2.9e-06 27.5 16.8 0.0056 17.0 5.0 2.8 2 0 0 2 2 2 2 RING-like domain PHD_2 PF13831.6 RLN95143.1 - 0.00028 20.4 2.0 0.00028 20.4 2.0 3.5 4 1 0 4 4 4 2 PHD-finger BET PF17035.5 RLN95143.1 - 0.0016 18.5 0.0 0.3 11.3 0.0 2.4 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation C1_2 PF03107.16 RLN95143.1 - 1.5 9.2 16.4 0.11 12.9 1.9 2.9 3 0 0 3 3 3 0 C1 domain SET PF00856.28 RLN95144.1 - 5.8e-08 33.3 0.0 1.4e-07 32.1 0.0 1.7 2 1 0 2 2 2 1 SET domain TPR_2 PF07719.17 RLN95144.1 - 0.51 10.6 2.7 0.51 10.6 0.8 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 RLN95145.1 - 8.2e-52 176.2 0.0 2.3e-51 174.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN95145.1 - 1.4e-44 152.3 0.0 2.5e-44 151.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 RLN95145.1 - 1.9e-26 92.5 0.1 3.6e-08 33.9 0.1 5.3 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN95145.1 - 1.3e-23 83.1 5.5 3.4e-05 24.3 0.1 7.6 6 2 2 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN95145.1 - 1.3e-15 57.2 7.3 0.11 12.9 0.0 8.5 5 1 4 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN95145.1 - 2.9e-15 54.8 0.1 0.87 10.4 0.1 10.4 8 2 3 11 11 11 2 Ankyrin repeat Podoplanin PF05808.11 RLN95145.1 - 0.0039 17.3 0.6 0.0074 16.4 0.6 1.6 1 0 0 1 1 1 1 Podoplanin Ank PF00023.30 RLN95145.1 - 0.023 15.2 0.2 95 3.7 0.1 5.5 6 1 0 6 6 6 0 Ankyrin repeat Haspin_kinase PF12330.8 RLN95145.1 - 0.031 13.2 0.0 0.054 12.4 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain Glyco_trans_4_5 PF16994.5 RLN95145.1 - 0.38 10.3 2.7 6.6 6.3 0.8 3.0 3 1 1 4 4 4 0 Glycosyl-transferase family 4 LRR_6 PF13516.6 RLN95147.1 - 9.4e-28 93.9 20.3 1.4e-05 24.8 0.4 9.1 9 0 0 9 9 9 8 Leucine Rich repeat LRR_4 PF12799.7 RLN95147.1 - 2.8e-13 49.8 1.9 0.034 14.6 0.0 5.2 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN95147.1 - 1.8e-07 30.7 0.5 17 6.4 0.0 7.4 9 0 0 9 9 9 2 Leucine Rich Repeat LRR_8 PF13855.6 RLN95147.1 - 4.3e-07 29.6 13.6 0.099 12.4 0.4 5.7 4 2 1 5 5 5 3 Leucine rich repeat DUF4396 PF14342.6 RLN95147.1 - 0.19 12.1 0.0 0.35 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) DUF3391 PF11871.8 RLN95148.1 - 0.012 16.1 2.4 0.018 15.6 2.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) FAP PF07174.11 RLN95148.1 - 0.17 11.3 13.1 0.22 11.0 13.1 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Amidase PF01425.21 RLN95149.1 - 0.065 12.2 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 Amidase Myb_DNA-bind_6 PF13921.6 RLN95150.1 - 5.7e-25 87.3 0.7 6.9e-15 55.1 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 RLN95150.1 - 1.5e-24 85.9 11.6 3.3e-13 49.6 0.9 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 RLN95150.1 - 0.1 13.0 2.3 1.8 9.0 0.1 2.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain AAA_16 PF13191.6 RLN95151.1 - 0.13 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Hist_deacetyl PF00850.19 RLN95153.1 - 4.2e-15 56.0 0.0 5.1e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain NEXCaM_BD PF16644.5 RLN95154.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Aa_trans PF01490.18 RLN95156.1 - 8.8e-11 41.1 2.4 1e-10 40.9 2.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 RLN95156.1 - 0.0043 16.1 1.7 0.0046 16.0 1.7 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family PDZ PF00595.24 RLN95157.1 - 0.001 19.3 0.0 0.0021 18.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RLN95157.1 - 0.0014 18.5 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain RapA_C PF12137.8 RLN95158.1 - 0.063 12.3 11.7 0.11 11.5 11.7 1.4 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal ColG_sub PF18496.1 RLN95158.1 - 0.22 11.7 0.0 0.46 10.7 0.0 1.4 1 0 0 1 1 1 0 Collagenase G catalytic helper subdomain LPP20 PF02169.16 RLN95158.1 - 3.5 8.0 9.1 19 5.7 5.8 2.7 1 1 1 2 2 2 0 LPP20 lipoprotein PDT PF00800.18 RLN95160.1 - 4.8e-38 130.8 0.1 4.8e-38 130.8 0.1 2.0 3 0 0 3 3 3 1 Prephenate dehydratase BrkDBD PF09607.10 RLN95160.1 - 9.5e-08 31.7 0.4 2.9e-07 30.2 0.4 1.8 1 0 0 1 1 1 1 Brinker DNA-binding domain CENP-B_N PF04218.13 RLN95160.1 - 2.2e-05 24.0 0.1 5.3e-05 22.8 0.1 1.6 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 RLN95160.1 - 7.7e-05 22.9 1.1 0.00026 21.2 1.1 1.9 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 RLN95160.1 - 0.00012 22.1 0.9 0.00043 20.3 0.9 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 RLN95160.1 - 0.011 15.5 0.5 0.028 14.2 0.5 1.7 1 0 0 1 1 1 0 Homeodomain-like domain ACT PF01842.25 RLN95160.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 ACT domain WD40 PF00400.32 RLN95161.1 - 3e-17 62.7 0.5 0.0018 19.1 0.0 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.8 RLN95161.1 - 2.4e-06 26.5 0.2 0.024 13.3 0.0 3.1 3 0 0 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RLN95161.1 - 5.5e-05 22.3 0.4 0.042 12.8 0.0 3.0 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein SNAP PF14938.6 RLN95162.1 - 8.8e-17 61.4 16.2 1.5e-16 60.7 16.2 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP DUF2052 PF09747.9 RLN95164.1 - 7.9 6.5 11.8 17 5.4 11.8 1.6 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) AMP-binding PF00501.28 RLN95165.1 - 3e-70 237.0 0.0 3.7e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN95165.1 - 0.00016 22.6 0.0 0.0004 21.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 RLN95166.1 - 3e-49 167.8 0.0 4.3e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN95166.1 - 6.4e-48 163.3 0.0 8.8e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN95166.1 - 0.004 17.1 0.6 0.024 14.5 0.6 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN95166.1 - 0.0053 15.6 0.1 0.0053 15.6 0.1 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 RLN95166.1 - 0.058 12.8 0.2 0.12 11.7 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2009 PF09418.10 RLN95167.1 - 2.9e-201 669.4 0.0 3.4e-201 669.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 RLN95167.1 - 6.9e-05 22.9 14.0 0.00012 22.2 12.7 2.0 2 0 0 2 2 2 1 B-box zinc finger CEBP_ZZ PF16366.5 RLN95167.1 - 0.01 16.1 11.4 0.021 15.1 11.4 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Pkinase PF00069.25 RLN95168.1 - 6.3e-49 166.7 0.0 9e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN95168.1 - 8.9e-44 149.7 0.0 1.2e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 RLN95168.1 - 0.0017 18.1 2.1 0.019 14.7 0.1 2.6 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 RLN95168.1 - 0.023 15.1 3.5 0.52 10.8 0.2 3.0 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) DAP10 PF07213.11 RLN95168.1 - 0.056 13.4 0.4 18 5.4 0.0 2.8 2 0 0 2 2 2 0 DAP10 membrane protein AbiEi_3_N PF17194.4 RLN95168.1 - 0.11 12.5 0.1 1.4 9.0 0.0 2.6 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain Pkinase_fungal PF17667.1 RLN95168.1 - 0.18 10.5 0.1 0.28 9.9 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 RLN95169.1 - 2.3e-48 164.9 0.0 3.3e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN95169.1 - 1.6e-47 162.0 0.0 2.2e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Arm_APC_u3 PF16629.5 RLN95169.1 - 0.032 13.8 0.0 0.76 9.3 0.0 2.2 2 0 0 2 2 2 0 Armadillo-associated region on APC Kdo PF06293.14 RLN95169.1 - 0.12 11.7 0.5 0.23 10.8 0.5 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 RLN95171.1 - 3.5e-27 94.1 2.9 3e-06 27.8 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 RLN95171.1 - 3.7e-14 52.4 0.2 0.0014 17.7 0.0 4.1 2 1 2 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 RLN95171.1 - 3.5e-13 49.6 0.0 0.011 16.0 0.0 4.6 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN95171.1 - 0.00081 18.1 0.1 0.25 10.0 0.1 2.6 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Hira PF07569.11 RLN95171.1 - 0.049 13.3 0.1 4.3 7.0 0.0 3.1 3 0 0 3 3 3 0 TUP1-like enhancer of split CDtoxinA PF03498.14 RLN95171.1 - 0.072 12.7 0.0 9.6 5.8 0.0 2.8 3 0 0 3 3 3 0 Cytolethal distending toxin A/C domain WD40_like PF17005.5 RLN95171.1 - 0.17 11.2 0.1 11 5.3 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain Thioredoxin_4 PF13462.6 RLN95173.1 - 0.13 12.4 1.1 0.55 10.4 0.1 2.5 1 1 1 2 2 2 0 Thioredoxin CLTH PF10607.9 RLN95174.1 - 1.4e-11 44.5 0.0 3.2e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Ank_2 PF12796.7 RLN95174.1 - 9.3e-09 35.8 0.0 2.4e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN95174.1 - 2.2e-07 31.0 0.5 0.00014 22.1 0.1 3.9 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN95174.1 - 4.2e-06 27.2 0.3 0.0048 17.4 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN95174.1 - 0.0039 17.6 0.1 3.7 8.4 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat PhoD PF09423.10 RLN95175.1 - 0.022 13.8 0.1 0.031 13.3 0.1 1.2 1 0 0 1 1 1 0 PhoD-like phosphatase Cwf_Cwc_15 PF04889.12 RLN95175.1 - 0.03 14.1 1.7 0.06 13.1 1.7 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HTH_32 PF13565.6 RLN95176.1 - 2.5e-17 63.2 19.9 6.3e-07 29.9 0.3 4.1 4 0 0 4 4 3 3 Homeodomain-like domain HTH_23 PF13384.6 RLN95176.1 - 4.4e-10 39.1 0.4 9.5e-05 22.1 0.1 3.0 2 0 0 2 2 2 2 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 RLN95176.1 - 1.8e-08 34.5 11.1 0.00051 20.2 0.8 4.3 5 0 0 5 5 5 2 Transposase HTH_29 PF13551.6 RLN95176.1 - 2.2e-07 30.8 4.5 0.0053 16.7 0.1 3.5 3 0 0 3 3 3 2 Winged helix-turn helix HTH_38 PF13936.6 RLN95176.1 - 4.3e-05 23.2 3.3 0.0053 16.5 0.0 3.5 4 0 0 4 4 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 RLN95176.1 - 4.9e-05 22.9 0.8 0.023 14.3 0.1 2.9 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_28 PF13518.6 RLN95176.1 - 9.1e-05 22.5 6.3 0.0051 16.9 0.1 3.5 3 0 0 3 3 3 2 Helix-turn-helix domain PAX PF00292.18 RLN95176.1 - 0.00026 20.9 6.3 0.051 13.5 0.2 3.0 3 0 0 3 3 3 2 'Paired box' domain HTH_Tnp_1 PF01527.20 RLN95176.1 - 0.00095 19.4 1.4 0.0042 17.4 0.2 2.7 2 0 0 2 2 2 1 Transposase Sigma70_r3 PF04539.16 RLN95176.1 - 0.0037 17.3 0.0 0.081 13.0 0.0 2.8 2 0 0 2 2 2 1 Sigma-70 region 3 AT_hook PF02178.19 RLN95176.1 - 0.004 16.9 8.6 2.5 8.2 2.2 3.9 3 0 0 3 3 3 1 AT hook motif MarR_2 PF12802.7 RLN95176.1 - 0.0059 16.5 0.4 0.7 9.8 0.1 3.3 2 0 0 2 2 2 1 MarR family HTH_DeoR PF08220.12 RLN95176.1 - 0.0098 15.6 1.4 0.74 9.6 0.1 2.8 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain HTH_24 PF13412.6 RLN95176.1 - 0.028 14.0 0.8 5.8 6.6 0.0 4.0 4 0 0 4 4 4 0 Winged helix-turn-helix DNA-binding DNA_meth_N PF18284.1 RLN95176.1 - 0.042 13.8 0.8 3 7.8 0.1 2.8 2 0 0 2 2 2 0 DNA methylase N-terminal domain Ground-like PF04155.18 RLN95176.1 - 0.048 14.3 2.8 13 6.5 0.1 3.3 3 0 0 3 3 3 0 Ground-like domain HTH_Tnp_ISL3 PF13542.6 RLN95176.1 - 0.071 12.5 10.2 0.27 10.7 0.1 5.0 5 0 0 5 5 5 0 Helix-turn-helix domain of transposase family ISL3 RPA_C PF08784.11 RLN95176.1 - 0.099 13.3 4.9 1.5 9.6 0.0 3.7 5 0 0 5 5 2 0 Replication protein A C terminal CENP-B_N PF04218.13 RLN95176.1 - 0.24 11.1 2.3 18 5.1 0.0 3.4 4 0 0 4 4 4 0 CENP-B N-terminal DNA-binding domain HTH_12 PF08461.10 RLN95176.1 - 0.31 11.0 7.7 2.3 8.2 0.0 3.4 4 0 0 4 4 3 0 Ribonuclease R winged-helix domain Sigma70_r4 PF04545.16 RLN95176.1 - 0.35 10.4 0.0 0.35 10.4 0.0 4.1 6 0 0 6 6 6 0 Sigma-70, region 4 HTH_AsnC-type PF13404.6 RLN95176.1 - 2.3 8.1 10.2 48 3.9 0.1 5.3 5 1 0 5 5 5 0 AsnC-type helix-turn-helix domain Gln-synt_C PF00120.24 RLN95177.1 - 4.1e-69 233.2 0.0 6e-69 232.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 RLN95177.1 - 0.074 12.9 0.1 0.22 11.4 0.1 1.8 1 1 0 1 1 1 0 Glutamine synthetase N-terminal domain Ins_P5_2-kin PF06090.12 RLN95178.1 - 1e-92 311.1 1.3 1.5e-92 310.6 1.3 1.2 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase MPM1 PF17234.2 RLN95178.1 - 0.029 14.6 0.1 0.054 13.8 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Cwf_Cwc_15 PF04889.12 RLN95178.1 - 0.041 13.6 10.5 0.04 13.6 8.4 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 RLN95178.1 - 7 4.8 10.3 12 4.0 10.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 RLN95179.1 - 1.5e-27 96.6 0.0 2.1e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN95179.1 - 4e-15 55.8 0.0 5.4e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAP30_Sin3_bdg PF13867.6 RLN95179.1 - 0.032 14.6 0.1 0.068 13.5 0.1 1.5 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Ank_5 PF13857.6 RLN95180.1 - 2.7e-30 104.0 22.5 0.00086 19.6 0.3 12.7 5 1 8 13 13 13 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN95180.1 - 1.7e-29 102.2 5.7 1.6e-07 31.8 0.0 6.0 1 1 7 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN95180.1 - 7.4e-27 93.4 8.9 0.00033 21.2 0.1 7.8 5 1 2 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN95180.1 - 1.5e-16 58.8 3.1 9.8 7.1 0.0 11.5 12 0 0 12 12 12 3 Ankyrin repeat DUF5049 PF16468.5 RLN95180.1 - 0.00017 21.4 0.0 75 3.3 0.0 6.5 4 2 3 7 7 7 0 Domain of unknown function (DUF5049) Ank PF00023.30 RLN95180.1 - 0.00083 19.7 2.0 95 3.7 0.2 7.5 4 2 2 6 6 6 0 Ankyrin repeat RB_A PF01858.17 RLN95181.1 - 6.3e-59 199.1 0.0 1.1e-58 198.4 0.0 1.4 1 0 0 1 1 1 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 RLN95181.1 - 5.4e-30 104.1 0.2 1.7e-29 102.5 0.0 1.9 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 RLN95181.1 - 3e-14 52.7 0.0 1.1e-13 50.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3452) Rb_C PF08934.10 RLN95181.1 - 0.00038 20.3 0.1 0.0012 18.7 0.0 1.9 2 0 0 2 2 2 1 Rb C-terminal domain Acyl-CoA_dh_1 PF00441.24 RLN95182.1 - 2e-42 144.9 3.7 2.4e-42 144.7 3.7 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 RLN95182.1 - 3.4e-24 85.6 2.4 3.8e-24 85.5 2.4 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PX PF00787.24 RLN95183.1 - 8.3e-12 45.1 0.2 1.9e-11 44.0 0.1 1.7 1 1 0 1 1 1 1 PX domain zf-RING_2 PF13639.6 RLN95183.1 - 1.1e-11 44.9 10.1 2.8e-11 43.5 10.1 1.7 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RLN95183.1 - 6.3e-10 39.2 7.2 1.1e-09 38.5 7.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 RLN95183.1 - 1.6e-06 27.9 7.9 1.9e-06 27.6 2.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RLN95183.1 - 2.9e-06 27.3 2.3 5.3e-06 26.4 2.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 RLN95183.1 - 4.7e-06 26.2 7.0 0.0003 20.5 7.0 2.5 1 1 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 RLN95183.1 - 7.7e-06 25.7 8.7 9.8e-06 25.3 7.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN95183.1 - 1.6e-05 24.8 4.8 3.2e-05 23.9 4.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN95183.1 - 0.00064 19.6 9.6 0.00065 19.6 7.9 2.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RLN95183.1 - 0.0013 18.5 9.9 0.0047 16.8 9.6 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 RLN95183.1 - 0.0055 16.6 0.1 0.0055 16.6 0.1 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 RLN95183.1 - 0.025 14.2 1.9 0.025 14.2 1.9 1.9 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 RLN95183.1 - 0.064 13.3 1.3 0.064 13.3 1.3 2.0 2 0 0 2 2 1 0 Zinc-finger FANCL_C PF11793.8 RLN95183.1 - 0.091 12.9 8.7 0.58 10.4 8.7 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 RLN95183.1 - 0.67 9.9 12.4 0.83 9.6 10.2 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 RLN95183.1 - 4 7.3 11.6 35 4.3 10.1 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain APH PF01636.23 RLN95184.1 - 1.2e-41 143.2 0.0 2.4e-41 142.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.24 RLN95184.1 - 2e-35 122.2 4.0 4.6e-35 121.0 4.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RLN95184.1 - 5.4e-18 65.0 0.0 1e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RLN95184.1 - 3e-12 47.0 5.5 6e-12 46.0 3.5 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RLN95184.1 - 1.1e-07 32.5 0.0 2.5e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain EcKinase PF02958.20 RLN95184.1 - 0.00013 21.4 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 RLN95184.1 - 0.0024 17.5 0.0 0.22 11.1 0.0 2.4 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 RLN95184.1 - 0.15 11.4 0.0 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 RLN95184.1 - 0.15 10.9 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EF-hand_1 PF00036.32 RLN95188.1 - 3.5e-06 26.2 0.9 0.087 12.4 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN95188.1 - 1.3e-05 24.7 0.3 0.13 12.2 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RLN95188.1 - 0.0021 18.5 0.4 5 7.6 0.0 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 RLN95188.1 - 0.0024 17.3 7.7 0.17 11.4 0.7 2.8 3 0 0 3 3 3 2 EF hand VCBS PF13517.6 RLN95188.1 - 0.012 16.2 2.2 1.2 9.8 0.1 2.9 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Asp-B-Hydro_N PF05279.11 RLN95188.1 - 0.11 12.5 0.4 0.52 10.3 0.1 2.0 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region PEPCK_ATP PF01293.20 RLN95189.1 - 4.7e-92 309.1 0.0 5.4e-92 308.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase PDZ_1 PF12812.7 RLN95189.1 - 0.1 12.6 0.0 0.78 9.8 0.0 2.2 2 0 0 2 2 2 0 PDZ-like domain C2 PF00168.30 RLN95192.1 - 8.5e-12 45.3 0.2 2.5e-11 43.8 0.1 1.8 2 0 0 2 2 2 1 C2 domain Arb2 PF09757.9 RLN95192.1 - 0.00034 19.8 0.0 0.00053 19.2 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain FYVE PF01363.21 RLN95192.1 - 0.0011 19.1 7.3 0.0021 18.1 7.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger Cluap1 PF10234.9 RLN95193.1 - 1.4e-97 326.3 16.2 2.2e-97 325.7 16.2 1.3 1 0 0 1 1 1 1 Clusterin-associated protein-1 Lebercilin PF15619.6 RLN95193.1 - 0.0062 16.2 21.5 0.018 14.7 21.5 1.8 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Ndc80_HEC PF03801.13 RLN95193.1 - 0.014 15.0 0.1 0.04 13.6 0.0 1.7 2 0 0 2 2 2 0 HEC/Ndc80p family PAD PF03068.15 RLN95193.1 - 0.12 11.4 1.6 0.2 10.6 1.6 1.3 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) Prominin PF05478.11 RLN95193.1 - 0.12 10.3 2.9 0.18 9.7 2.9 1.3 1 0 0 1 1 1 0 Prominin tRNA-synt_1b PF00579.25 RLN95193.1 - 0.26 10.6 3.6 0.1 11.9 0.4 1.9 2 1 0 2 2 2 0 tRNA synthetases class I (W and Y) U1snRNP70_N PF12220.8 RLN95194.1 - 4.9 7.9 12.3 5.5 7.7 3.3 3.1 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal HemY_N PF07219.13 RLN95194.1 - 6.9 6.9 9.5 2.3 8.5 3.2 2.9 2 0 0 2 2 2 0 HemY protein N-terminus Abhydrolase_6 PF12697.7 RLN95197.1 - 3.8e-07 30.9 0.7 9.8e-07 29.6 0.7 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN95197.1 - 6.1e-06 26.1 0.4 0.00035 20.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN95197.1 - 0.014 14.7 0.0 0.035 13.4 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 RLN95197.1 - 0.044 13.4 1.1 0.17 11.5 0.0 2.1 2 1 1 3 3 3 0 Putative esterase Thioesterase PF00975.20 RLN95197.1 - 0.074 13.1 0.3 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.13 RLN95197.1 - 0.11 12.2 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein 7tm_3 PF00003.22 RLN95198.1 - 2.2e-40 138.9 22.8 3.9e-40 138.1 22.8 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR HIG_1_N PF04588.13 RLN95199.1 - 2.5e-05 24.4 0.4 2.5e-05 24.4 0.4 2.1 3 0 0 3 3 3 1 Hypoxia induced protein conserved region ENOD93 PF03386.14 RLN95199.1 - 0.00045 20.0 1.2 0.00088 19.1 1.2 1.4 1 0 0 1 1 1 1 Early nodulin 93 ENOD93 protein QCR10 PF09796.9 RLN95199.1 - 0.69 10.0 0.1 0.69 10.0 0.1 2.1 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DSPc PF00782.20 RLN95201.1 - 9.5e-05 22.2 0.1 0.00013 21.8 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PNP_UDP_1 PF01048.20 RLN95202.1 - 1.8e-17 63.4 0.2 2e-17 63.2 0.2 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily tRNA-synt_2d PF01409.20 RLN95203.1 - 6.8e-50 169.8 0.9 1.5e-49 168.7 0.9 1.5 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 RLN95203.1 - 4e-20 72.0 0.9 8.4e-20 71.0 0.1 1.9 3 0 0 3 3 3 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.20 RLN95203.1 - 0.067 12.3 0.3 8.3 5.4 0.1 2.4 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) PP2C PF00481.21 RLN95204.1 - 5.5e-11 42.6 0.0 8.9e-06 25.5 0.0 3.7 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 RLN95204.1 - 8.7e-05 22.3 0.1 0.0004 20.1 0.1 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C DENN PF02141.21 RLN95205.1 - 1.2e-25 90.6 3.3 4.9e-25 88.6 1.1 2.7 2 1 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.19 RLN95205.1 - 0.085 12.9 0.2 0.24 11.4 0.2 1.7 1 0 0 1 1 1 0 dDENN domain UPF0029 PF01205.19 RLN95206.1 - 2.9e-27 95.0 0.0 4.7e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF1949 PF09186.11 RLN95206.1 - 0.00011 22.1 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1949) RCC1 PF00415.18 RLN95207.1 - 3e-44 149.4 5.2 2e-10 41.1 0.1 6.8 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat ABC_tran PF00005.27 RLN95207.1 - 1.7e-43 148.4 12.3 2.2e-23 83.3 0.0 3.7 4 1 0 4 4 2 2 ABC transporter RCC1_2 PF13540.6 RLN95207.1 - 6.1e-13 48.2 27.0 3.7e-09 36.1 0.5 7.0 8 0 0 8 8 8 2 Regulator of chromosome condensation (RCC1) repeat AAA_21 PF13304.6 RLN95207.1 - 2.1e-12 47.5 9.8 0.015 15.1 0.0 5.5 5 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system PA PF02225.22 RLN95207.1 - 1.6e-08 34.4 0.0 0.0012 18.8 0.0 3.4 3 0 0 3 3 2 2 PA domain ABC_tran_Xtn PF12848.7 RLN95207.1 - 3.3e-07 30.2 7.9 3.3e-07 30.2 7.9 5.9 6 1 1 7 7 2 1 ABC transporter SMC_N PF02463.19 RLN95207.1 - 5.7e-07 29.2 11.9 0.024 14.1 0.0 4.9 4 2 1 5 5 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RLN95207.1 - 8.9e-07 28.6 1.1 0.014 15.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 RLN95207.1 - 2.4e-05 24.8 0.1 0.48 10.8 0.0 3.6 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) EF-hand_6 PF13405.6 RLN95207.1 - 6.3e-05 22.6 0.1 0.00026 20.7 0.1 2.0 2 0 0 2 2 1 1 EF-hand domain AAA_22 PF13401.6 RLN95207.1 - 0.00011 22.4 0.0 0.054 13.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 RLN95207.1 - 0.00015 22.4 1.4 0.0051 17.3 0.1 6.9 5 3 0 5 5 3 2 AAA domain AAA_33 PF13671.6 RLN95207.1 - 0.0011 19.2 0.0 0.84 9.8 0.0 3.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 RLN95207.1 - 0.0011 18.9 4.3 0.0078 16.1 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase EF-hand_7 PF13499.6 RLN95207.1 - 0.0013 19.1 0.0 0.11 13.0 0.0 3.1 2 0 0 2 2 2 1 EF-hand domain pair NACHT PF05729.12 RLN95207.1 - 0.0018 18.3 1.9 0.41 10.6 0.1 2.7 2 0 0 2 2 2 1 NACHT domain EF-hand_1 PF00036.32 RLN95207.1 - 0.0021 17.5 0.3 0.0055 16.2 0.3 1.8 1 0 0 1 1 1 1 EF hand AAA_28 PF13521.6 RLN95207.1 - 0.0044 17.3 1.0 2.2 8.5 0.0 4.1 4 0 0 4 4 3 1 AAA domain IQ PF00612.27 RLN95207.1 - 0.0045 16.7 0.0 0.017 14.9 0.0 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif RNA_helicase PF00910.22 RLN95207.1 - 0.007 16.7 0.0 1.5 9.3 0.0 2.8 2 0 0 2 2 2 1 RNA helicase NTPase_1 PF03266.15 RLN95207.1 - 0.0076 16.2 0.1 1.1 9.1 0.1 2.9 2 0 0 2 2 2 1 NTPase AAA_14 PF13173.6 RLN95207.1 - 0.0082 16.2 0.1 4.1 7.5 0.1 2.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 RLN95207.1 - 0.02 15.0 4.4 0.022 14.9 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_24 PF13479.6 RLN95207.1 - 0.036 13.8 7.5 0.31 10.7 0.1 3.5 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 RLN95207.1 - 0.036 14.3 0.4 4.5 7.5 0.1 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 RLN95207.1 - 0.051 13.1 0.2 7.2 6.1 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region EF-hand_8 PF13833.6 RLN95207.1 - 0.058 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair AAA_16 PF13191.6 RLN95207.1 - 0.058 13.8 14.1 0.28 11.5 0.0 4.8 5 0 0 5 5 4 0 AAA ATPase domain EF-hand_5 PF13202.6 RLN95207.1 - 0.082 12.4 0.7 0.2 11.2 0.7 1.7 1 0 0 1 1 1 0 EF hand ATP-synt_ab PF00006.25 RLN95207.1 - 0.11 12.1 1.2 13 5.3 0.0 2.8 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 RLN95207.1 - 0.41 10.6 2.0 4.4 7.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FAM194 PF14977.6 RLN95209.1 - 0.00035 20.0 0.0 0.00061 19.2 0.0 1.4 1 0 0 1 1 1 1 FAM194 protein Pkinase PF00069.25 RLN95210.1 - 2.1e-55 187.9 0.0 3e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN95210.1 - 2.9e-48 164.4 0.0 3.8e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EphA2_TM PF14575.6 RLN95210.1 - 6e-05 23.9 0.0 0.00011 23.1 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 RLN95210.1 - 0.0006 20.1 0.0 0.00094 19.5 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator APH PF01636.23 RLN95210.1 - 0.0033 17.4 0.1 0.0066 16.4 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family TMIE PF16038.5 RLN95210.1 - 0.0077 16.1 1.0 0.017 14.9 1.0 1.5 1 0 0 1 1 1 1 TMIE protein Mucin PF01456.17 RLN95210.1 - 0.013 15.5 0.7 0.028 14.4 0.7 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Comm PF15957.5 RLN95210.1 - 0.023 15.0 0.0 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 Commissureless WBP-1 PF11669.8 RLN95210.1 - 0.04 14.6 0.3 0.08 13.6 0.3 1.4 1 0 0 1 1 1 0 WW domain-binding protein 1 Rhabdo_glycop PF00974.18 RLN95210.1 - 0.041 12.3 0.4 0.069 11.6 0.4 1.3 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein MLANA PF14991.6 RLN95210.1 - 0.076 13.3 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein melan-A TMEM51 PF15345.6 RLN95210.1 - 0.086 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 TMEM100 PF16311.5 RLN95210.1 - 0.13 11.8 0.2 0.23 11.0 0.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 Haspin_kinase PF12330.8 RLN95210.1 - 0.13 11.1 0.0 0.36 9.7 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Adeno_E3_CR2 PF02439.15 RLN95210.1 - 0.22 11.3 6.9 0.44 10.4 6.9 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.10 RLN95210.1 - 0.61 9.5 4.3 1.8 8.1 4.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Elicitin PF00964.17 RLN95211.1 - 1e-15 57.5 7.9 3e-15 56.1 7.9 1.8 1 0 0 1 1 1 1 Elicitin BUD22 PF09073.10 RLN95211.1 - 2 7.6 10.0 2.5 7.4 10.0 1.1 1 0 0 1 1 1 0 BUD22 Ank_2 PF12796.7 RLN95212.1 - 7.8e-92 302.0 21.1 2.4e-16 60.1 0.3 9.9 3 3 5 10 10 10 9 Ankyrin repeats (3 copies) Mo25 PF08569.11 RLN95212.1 - 1.4e-89 300.7 7.4 1.7e-59 201.9 0.1 2.8 2 1 1 3 3 3 2 Mo25-like Ank_4 PF13637.6 RLN95212.1 - 2.9e-78 257.3 23.7 2e-13 50.5 0.0 12.4 8 3 3 12 12 12 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN95212.1 - 1.7e-75 248.1 41.3 9.4e-09 35.4 0.2 15.8 4 3 12 16 16 16 16 Ankyrin repeats (many copies) Ank PF00023.30 RLN95212.1 - 7.5e-67 219.1 49.9 4.7e-07 30.0 0.3 17.1 16 1 1 17 17 17 13 Ankyrin repeat Ank_3 PF13606.6 RLN95212.1 - 1.2e-66 212.7 20.9 4.6e-05 23.5 0.0 17.4 18 0 0 18 18 18 14 Ankyrin repeat Joubert PF15392.6 RLN95212.1 - 0.2 11.3 3.7 3.7 7.2 0.6 2.4 2 0 0 2 2 2 0 Joubert syndrome-associated VWA_3_C PF18571.1 RLN95212.1 - 6.1 6.8 7.9 7.6 6.5 0.0 4.9 5 1 0 5 5 5 0 von Willebrand factor type A C-terminal domain Elicitin PF00964.17 RLN95213.1 - 1.1e-17 63.9 7.6 1.1e-17 63.9 7.6 2.1 2 0 0 2 2 2 1 Elicitin Pkinase PF00069.25 RLN95214.1 - 5.3e-52 176.8 0.0 7e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN95214.1 - 2.6e-45 154.7 0.0 3.6e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF347 PF03988.12 RLN95214.1 - 0.01 16.0 0.4 0.01 16.0 0.4 1.8 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Haspin_kinase PF12330.8 RLN95214.1 - 0.03 13.2 0.0 0.096 11.6 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 RLN95214.1 - 0.035 14.0 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Podoplanin PF05808.11 RLN95214.1 - 0.061 13.4 2.0 0.11 12.6 2.0 1.4 1 0 0 1 1 1 0 Podoplanin Kdo PF06293.14 RLN95214.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4131 PF13567.6 RLN95214.1 - 0.12 12.0 0.1 4.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Peptidase_M17 PF00883.21 RLN95215.1 - 7.8e-58 196.2 1.1 1.3e-57 195.5 1.1 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 RLN95215.1 - 4.6e-15 55.9 5.6 8e-15 55.2 1.7 3.0 3 1 0 3 3 3 1 M17 aminopeptidase N-terminal domain 2 NUDIX PF00293.28 RLN95216.1 - 4.3e-16 59.1 0.2 6.7e-16 58.5 0.2 1.2 1 0 0 1 1 1 1 NUDIX domain Aldo_ket_red PF00248.21 RLN95218.1 - 3.8e-62 210.2 0.0 4.8e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4588 PF15251.6 RLN95219.1 - 0.12 12.1 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) Collagen PF01391.18 RLN95219.1 - 1.5 8.7 10.8 0.72 9.7 2.8 2.3 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Pirin PF02678.16 RLN95220.1 - 1.1e-28 99.4 0.0 2.3e-28 98.3 0.0 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 RLN95220.1 - 1.8e-26 92.5 0.1 4.6e-26 91.2 0.0 1.7 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin_C_2 PF17954.1 RLN95220.1 - 0.033 14.4 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain Myb_DNA-binding PF00249.31 RLN95221.1 - 1.1e-10 41.5 0.0 6.7e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN95221.1 - 0.022 15.0 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 RLN95223.1 - 5.6e-08 32.9 0.5 1.3e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain zf-RING_2 PF13639.6 RLN95224.1 - 1e-09 38.5 11.6 2.3e-09 37.4 11.6 1.6 1 0 0 1 1 1 1 Ring finger domain PX PF00787.24 RLN95224.1 - 1.6e-08 34.5 0.4 3.8e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 PX domain zf-rbx1 PF12678.7 RLN95224.1 - 6.4e-07 29.6 9.3 2.2e-06 27.9 9.3 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 RLN95224.1 - 8e-07 28.7 4.4 8e-07 28.7 4.4 2.6 2 1 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 RLN95224.1 - 6.1e-05 23.0 2.3 0.00014 21.9 2.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RLN95224.1 - 0.00034 20.4 7.4 0.00069 19.4 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN95224.1 - 0.0008 19.3 8.8 0.0022 17.9 8.8 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RLN95224.1 - 0.00092 19.0 13.1 0.0036 17.1 13.1 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN95224.1 - 0.004 17.1 5.0 0.004 17.1 5.0 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RLN95224.1 - 0.0043 16.9 10.4 0.0043 16.9 10.4 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 RLN95224.1 - 0.018 15.2 7.3 0.1 12.8 7.3 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain WD40 PF00400.32 RLN95225.1 - 1.4e-30 104.8 12.4 1.5e-08 35.2 0.2 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN95225.1 - 5.7e-13 49.0 0.0 0.0067 16.7 0.0 4.5 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RLN95225.1 - 0.0023 17.9 0.0 1 9.2 0.0 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Mitoc_L55 PF09776.9 RLN95225.1 - 0.27 11.0 1.6 0.54 10.0 1.6 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 Myb_DNA-binding PF00249.31 RLN95226.1 - 4.8e-11 42.7 0.0 6.1e-10 39.1 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain TT_ORF1 PF02956.14 RLN95226.1 - 0.17 10.5 2.9 0.18 10.4 2.9 1.1 1 0 0 1 1 1 0 TT viral orf 1 PCNA_C PF02747.15 RLN95227.1 - 1.7e-23 83.2 0.0 1.9e-23 83.0 0.0 1.0 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Aa_trans PF01490.18 RLN95228.1 - 1.5e-71 241.3 21.3 1.9e-71 240.9 21.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1656 PF07869.12 RLN95228.1 - 0.039 14.0 0.5 0.039 14.0 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) SPC12 PF06645.13 RLN95228.1 - 0.099 12.7 1.8 0.29 11.2 0.1 2.7 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Pirin PF02678.16 RLN95230.1 - 1.5e-27 95.6 0.0 3.2e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 RLN95230.1 - 5.4e-24 84.5 0.0 1.8e-23 82.9 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin_C_2 PF17954.1 RLN95230.1 - 0.04 14.1 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain Pkinase_Tyr PF07714.17 RLN95231.1 - 9.7e-42 143.0 0.0 1.5e-41 142.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN95231.1 - 1.1e-34 120.0 0.0 1.9e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.23 RLN95231.1 - 1.1e-21 76.1 25.2 0.011 15.7 0.0 16.1 19 2 0 19 19 19 6 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN95231.1 - 2e-10 40.0 18.7 2.7 8.5 0.0 11.3 11 2 2 13 13 13 5 HEAT repeat HEAT_EZ PF13513.6 RLN95231.1 - 2.5e-09 37.4 38.2 0.0002 21.8 0.4 11.1 10 3 1 11 11 11 3 HEAT-like repeat HEAT_2 PF13646.6 RLN95231.1 - 0.015 15.7 55.7 0.41 11.1 2.7 10.3 3 2 11 14 14 14 0 HEAT repeats Tex_N PF09371.10 RLN95231.1 - 0.03 14.0 3.3 68 3.1 0.0 6.2 5 3 3 8 8 8 0 Tex-like protein N-terminal domain DUF5388 PF17363.2 RLN95231.1 - 0.053 13.7 1.2 21 5.4 0.1 3.2 2 0 0 2 2 2 0 Family of unknown function (DUF5388) HemN_C PF06969.16 RLN95231.1 - 0.12 12.5 0.9 35 4.6 0.0 3.2 3 0 0 3 3 3 0 HemN C-terminal domain HEAT_PBS PF03130.16 RLN95231.1 - 5.7 7.9 43.5 10 7.2 0.2 12.6 15 2 2 17 17 17 0 PBS lyase HEAT-like repeat 2OG-FeII_Oxy_3 PF13640.6 RLN95233.1 - 0.00016 22.5 0.3 0.0007 20.4 0.2 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 RLN95234.1 - 2.2e-07 31.7 0.4 6.5e-07 30.2 0.4 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FANCI_S1 PF14675.6 RLN95234.1 - 0.0091 15.6 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 FANCI solenoid 1 zf-PARP PF00645.18 RLN95235.1 - 1.2e-05 26.1 0.2 2.1e-05 25.3 0.2 1.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region MOZ_SAS PF01853.18 RLN95236.1 - 4e-27 95.0 0.2 4.9e-27 94.7 0.2 1.1 1 0 0 1 1 1 1 MOZ/SAS family Fez1 PF06818.15 RLN95237.1 - 0.0013 19.3 13.8 0.0013 19.3 13.8 7.4 2 2 5 7 7 7 2 Fez1 SlyX PF04102.12 RLN95237.1 - 0.0014 19.2 4.1 0.0014 19.2 4.1 15.0 7 4 9 16 16 16 1 SlyX TPR_MLP1_2 PF07926.12 RLN95237.1 - 0.0036 17.4 10.2 0.0036 17.4 10.2 11.4 4 2 7 11 11 11 4 TPR/MLP1/MLP2-like protein Ank_2 PF12796.7 RLN95238.1 - 4.9e-19 68.7 0.9 1.9e-12 47.6 0.5 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN95238.1 - 1.2e-16 60.6 0.1 0.00012 22.3 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN95238.1 - 1.1e-13 51.3 0.3 0.0005 20.6 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN95238.1 - 4e-12 45.2 1.2 0.0059 17.0 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 RLN95238.1 - 8.3e-11 41.8 2.9 0.0049 17.3 0.1 4.8 2 1 2 4 4 4 3 Ankyrin repeat FYVE PF01363.21 RLN95238.1 - 8e-08 32.3 15.8 1.4e-07 31.5 15.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger PDZ PF00595.24 RLN95238.1 - 0.003 17.9 0.0 0.0073 16.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Tctex-1 PF03645.13 RLN95239.1 - 2e-21 76.1 0.1 2.9e-21 75.6 0.1 1.3 1 0 0 1 1 1 1 Tctex-1 family ATP-synt_DE_N PF02823.16 RLN95240.1 - 1.3e-16 60.2 0.7 1.9e-16 59.7 0.1 1.5 2 0 0 2 2 2 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF212 PF02681.14 RLN95240.1 - 0.04 14.1 1.5 0.073 13.2 0.0 2.1 2 1 1 3 3 3 0 Divergent PAP2 family zf-met2 PF12907.7 RLN95241.1 - 0.078 13.1 4.3 0.87 9.8 4.3 2.5 1 1 0 1 1 1 0 Zinc-binding FMN_dh PF01070.18 RLN95242.1 - 4.7e-30 104.8 0.1 5.2e-30 104.6 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase tRNA-synt_1g PF09334.11 RLN95243.1 - 4.6e-11 42.1 1.0 5.4e-11 41.9 1.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 RLN95243.1 - 2e-07 29.7 0.0 2.1e-07 29.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 RLN95243.1 - 0.0097 15.3 0.1 0.011 15.2 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Phage_tail_NK PF16532.5 RLN95243.1 - 0.087 12.4 0.0 0.095 12.3 0.0 1.1 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales Sugarporin_N PF11471.8 RLN95243.1 - 0.17 11.8 1.4 0.26 11.3 1.4 1.3 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Oxidored_FMN PF00724.20 RLN95244.1 - 4.9e-20 72.1 0.0 5.6e-20 71.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PAE PF03283.13 RLN95245.1 - 5.3e-14 52.1 0.7 9e-14 51.4 0.7 1.3 1 1 0 1 1 1 1 Pectinacetylesterase DUF2235 PF09994.9 RLN95245.1 - 0.0044 16.4 0.0 0.025 13.9 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_3 PF07859.13 RLN95245.1 - 0.13 12.1 0.0 0.5 10.2 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold adh_short PF00106.25 RLN95246.1 - 8.3e-36 123.3 1.7 1e-35 123.0 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN95246.1 - 3.1e-24 85.8 0.4 3.7e-24 85.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 RLN95246.1 - 1.5e-07 31.5 0.6 3.2e-07 30.4 0.2 1.7 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 RLN95246.1 - 7.2e-06 26.0 0.2 1.1e-05 25.4 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN95246.1 - 9.1e-05 22.0 0.1 0.00019 21.0 0.1 1.5 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 RLN95246.1 - 0.00079 19.1 0.3 0.003 17.1 0.1 1.8 2 0 0 2 2 2 1 NmrA-like family ADH_zinc_N PF00107.26 RLN95246.1 - 0.011 15.7 0.3 0.02 14.9 0.3 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.17 RLN95246.1 - 0.028 13.5 0.1 0.081 12.0 0.1 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.25 RLN95247.1 - 3.2e-33 114.8 0.5 1.2e-24 86.8 0.4 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN95247.1 - 7.9e-21 74.7 0.1 4e-16 59.3 0.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 RLN95247.1 - 0.0001 22.2 0.1 0.0002 21.3 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 RLN95247.1 - 0.0019 18.1 0.1 0.0034 17.3 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN95247.1 - 0.0051 16.3 0.0 0.0065 16.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 RLN95247.1 - 0.015 14.9 0.1 0.026 14.1 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family CBM_6 PF03422.15 RLN95247.1 - 0.071 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) PAE PF03283.13 RLN95248.1 - 8.6e-14 51.4 0.7 1.5e-13 50.7 0.7 1.4 1 0 0 1 1 1 1 Pectinacetylesterase DUF2235 PF09994.9 RLN95248.1 - 0.022 14.1 0.0 0.064 12.6 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Nucleo_P87 PF07267.11 RLN95248.1 - 0.49 9.2 6.7 0.64 8.8 6.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Hamartin PF04388.12 RLN95248.1 - 4.5 5.8 5.2 5.3 5.6 5.2 1.1 1 0 0 1 1 1 0 Hamartin protein Arm PF00514.23 RLN95250.1 - 5.8e-08 32.5 50.8 0.12 12.5 0.5 14.1 15 0 0 15 15 15 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN95250.1 - 2.9e-05 24.4 1.5 2.9e-05 24.4 1.5 11.8 8 4 2 11 11 11 1 HEAT repeats Cnd1 PF12717.7 RLN95250.1 - 0.0006 19.9 1.0 4.3 7.4 0.0 5.2 4 1 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Ribosomal_L29 PF00831.23 RLN95253.1 - 7.5e-19 67.5 7.2 5.6e-18 64.7 0.3 2.2 2 0 0 2 2 2 2 Ribosomal L29 protein CCDC-167 PF15188.6 RLN95253.1 - 0.0076 16.6 4.9 0.42 11.0 0.4 2.2 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 167 TolA_bind_tri PF16331.5 RLN95253.1 - 0.016 15.3 1.3 0.016 15.3 1.3 2.4 2 1 0 2 2 2 0 TolA binding protein trimerisation PRKG1_interact PF15898.5 RLN95253.1 - 1.3 9.9 10.8 1.8e+02 3.1 10.8 2.2 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain PRKCSH-like PF12999.7 RLN95253.1 - 1.4 8.7 3.0 1.3 8.8 2.3 1.4 1 1 0 1 1 1 0 Glucosidase II beta subunit-like PLDc_2 PF13091.6 RLN95254.1 - 5.5e-16 58.7 0.0 3.1e-11 43.3 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 RLN95254.1 - 6.5e-08 32.4 8.4 9.2e-05 22.5 0.3 3.3 3 1 0 3 3 3 2 Phospholipase D Active site motif Sel1 PF08238.12 RLN95255.1 - 5.1e-05 23.8 0.3 0.14 12.9 0.0 3.1 3 0 0 3 3 3 2 Sel1 repeat Destabilase PF05497.12 RLN95255.1 - 0.007 16.7 3.1 1.5 9.1 0.6 2.1 1 1 1 2 2 2 2 Destabilase Pkinase PF00069.25 RLN95258.1 - 4.6e-10 39.3 0.0 5.7e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN95258.1 - 5.8e-09 35.6 0.0 6.7e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase GCS PF03074.16 RLN95259.1 - 0.078 12.3 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Glutamate-cysteine ligase TauD PF02668.16 RLN95260.1 - 1e-57 196.0 4.2 5.9e-56 190.2 4.2 2.1 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3746 PF12562.8 RLN95260.1 - 0.019 14.8 0.1 0.048 13.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3746) PTR2 PF00854.21 RLN95261.1 - 1.5e-15 56.9 7.6 1.5e-15 56.9 7.6 1.9 2 1 0 2 2 2 1 POT family TRAM PF01938.20 RLN95261.1 - 0.066 13.2 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 TRAM domain Peptidase_M50B PF13398.6 RLN95261.1 - 0.23 11.1 10.9 0.46 10.1 1.2 2.5 2 0 0 2 2 2 0 Peptidase M50B-like PTR2 PF00854.21 RLN95262.1 - 2.2e-38 132.2 11.2 4e-38 131.3 11.2 1.4 1 0 0 1 1 1 1 POT family ABC_membrane PF00664.23 RLN95263.1 - 8.6e-54 183.0 5.8 1.4e-53 182.4 5.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN95263.1 - 1e-08 35.8 0.0 1.9e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 RLN95263.1 - 0.0002 21.0 0.1 0.00073 19.2 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN95263.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 RLN95263.1 - 0.019 15.4 0.0 0.041 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 RLN95263.1 - 0.043 13.5 0.0 0.059 13.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 RLN95263.1 - 0.051 13.4 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 RLN95263.1 - 0.09 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 RLN95263.1 - 0.13 11.9 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RLN95263.1 - 0.16 12.3 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RLN95263.1 - 0.19 12.3 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 RLN95263.1 - 0.25 11.8 0.1 0.45 11.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain Aa_trans PF01490.18 RLN95266.1 - 6.8e-58 196.3 18.6 8.5e-58 196.0 18.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 RLN95266.1 - 4.5e-09 35.6 30.2 9.4e-05 21.4 15.7 2.0 2 0 0 2 2 2 2 Amino acid permease Trp_Tyr_perm PF03222.13 RLN95266.1 - 1.8e-08 33.8 16.3 1.8e-08 33.8 16.3 1.5 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Sel1 PF08238.12 RLN95267.1 - 3.4e-36 122.9 13.1 9.6e-10 38.8 0.1 5.7 6 0 0 6 6 6 5 Sel1 repeat DUF1858 PF08984.11 RLN95267.1 - 0.12 12.5 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) MIT PF04212.18 RLN95267.1 - 0.65 10.1 3.6 10 6.3 0.1 3.7 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 RLN95267.1 - 4.9 7.9 7.3 5.9 7.6 0.1 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat ACPS PF01648.20 RLN95268.1 - 1.1e-16 61.0 0.0 1.2e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily K_oxygenase PF13434.6 RLN95268.1 - 0.083 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GAF_2 PF13185.6 RLN95270.1 - 8.2e-14 52.1 2.1 3.2e-05 24.2 0.0 5.6 6 0 0 6 6 6 2 GAF domain EF-hand_7 PF13499.6 RLN95270.1 - 5.1e-10 39.7 0.0 2.4e-09 37.5 0.0 2.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RLN95270.1 - 0.00025 20.8 1.1 0.0075 16.1 0.0 3.5 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN95270.1 - 0.0024 17.7 0.0 0.58 10.2 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 RLN95270.1 - 0.0074 15.8 0.2 0.045 13.3 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 RLN95270.1 - 0.016 14.7 0.0 0.25 10.9 0.0 2.5 2 0 0 2 2 2 0 EF hand IQ PF00612.27 RLN95270.1 - 9.4 6.3 27.6 5.5 7.1 2.6 4.5 4 0 0 4 4 4 0 IQ calmodulin-binding motif DUF1336 PF07059.12 RLN95271.1 - 2.8e-35 122.4 0.0 3.8e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) PH PF00169.29 RLN95271.1 - 3.3e-07 30.7 0.0 7.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN95271.1 - 0.0049 17.1 0.0 0.036 14.4 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 RLN95271.1 - 0.12 12.8 0.5 0.25 11.8 0.2 1.6 2 0 0 2 2 2 0 Pleckstrin homology domain Abhydrolase_3 PF07859.13 RLN95272.1 - 1.1e-35 123.5 0.2 1.7e-35 122.8 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN95272.1 - 3.8e-12 45.8 0.0 5.6e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 RLN95272.1 - 4.5e-05 23.0 0.0 8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 RLN95272.1 - 0.0038 16.5 0.1 0.02 14.2 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 RLN95273.1 - 1.9e-30 106.3 1.5 2.3e-29 102.8 1.5 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RLN95273.1 - 2.1e-07 30.1 0.0 3.2e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase DLH PF01738.18 RLN95273.1 - 0.15 11.6 0.0 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF4131 PF13567.6 RLN95273.1 - 2.6 7.6 5.1 4.8 6.8 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Kazal_1 PF00050.21 RLN95274.1 - 2.6e-09 36.9 3.7 5.7e-08 32.7 1.1 2.2 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 RLN95274.1 - 5.9e-09 35.9 1.8 5.9e-09 35.9 1.8 2.1 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Pkinase PF00069.25 RLN95275.1 - 7.5e-68 228.7 0.0 7.8e-67 225.4 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN95275.1 - 5.2e-35 121.0 0.0 4.2e-27 95.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase KA1 PF02149.19 RLN95275.1 - 2.4e-09 36.9 0.1 5.7e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 AdenylateSensor PF16579.5 RLN95275.1 - 3.5e-09 37.1 1.0 1.5e-08 35.1 0.9 2.1 1 1 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 RLN95275.1 - 5.2e-07 29.3 0.0 1.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN95275.1 - 0.0094 15.9 0.3 0.021 14.8 0.3 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 RLN95275.1 - 0.016 14.8 0.2 0.058 13.0 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Haspin_kinase PF12330.8 RLN95275.1 - 0.075 12.0 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain HTH_Tnp_Tc5 PF03221.16 RLN95276.1 - 3e-22 78.4 1.1 1.2e-11 44.5 0.0 2.7 3 0 0 3 3 3 2 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 RLN95276.1 - 0.069 12.9 0.3 3.6 7.4 0.0 2.8 2 0 0 2 2 2 0 helix-turn-helix, Psq domain WD40 PF00400.32 RLN95277.1 - 1e-18 67.3 18.3 3.1e-07 31.0 0.2 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 RLN95277.1 - 4e-17 62.2 0.1 5.7e-16 58.5 0.0 2.5 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 RLN95277.1 - 2.8e-08 34.0 0.4 0.021 15.1 0.0 3.3 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 RLN95277.1 - 0.11 10.5 0.3 0.46 8.4 0.1 2.0 1 1 0 1 1 1 0 IKI3 family BUD22 PF09073.10 RLN95277.1 - 0.16 11.3 10.6 0.26 10.6 10.6 1.3 1 0 0 1 1 1 0 BUD22 Tankyrase_bdg_C PF15327.6 RLN95277.1 - 0.18 12.2 3.3 9 6.7 0.3 2.3 2 0 0 2 2 2 0 Tankyrase binding protein C terminal domain Pox_Ag35 PF03286.14 RLN95277.1 - 0.24 11.2 9.4 0.6 9.9 1.2 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RXT2_N PF08595.11 RLN95277.1 - 6.1 6.8 9.5 3.3 7.7 1.1 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal FAM176 PF14851.6 RLN95277.1 - 6.5 6.4 8.5 1 9.0 0.3 2.4 2 0 0 2 2 2 0 FAM176 family RNA_pol_3_Rpc31 PF11705.8 RLN95277.1 - 8.8 6.5 19.7 3.6 7.8 3.6 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 FAD_binding_3 PF01494.19 RLN95280.1 - 4.4e-48 164.3 0.0 2.8e-47 161.7 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain Bd3614_N PF14442.6 RLN95280.1 - 0.003 17.8 4.3 0.015 15.6 4.3 2.2 1 0 0 1 1 1 1 Bd3614-like deaminase N-terminal Nuc_sug_transp PF04142.15 RLN95281.1 - 2e-26 92.9 5.0 2.6e-26 92.6 5.0 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 RLN95281.1 - 1e-05 24.9 2.1 1.4e-05 24.4 2.1 1.1 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 RLN95281.1 - 3.7e-05 23.1 5.9 0.00015 21.1 6.3 1.7 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 RLN95281.1 - 0.033 14.4 15.2 0.34 11.1 6.9 2.6 2 1 0 2 2 2 0 EamA-like transporter family CarS-like PF01864.17 RLN95281.1 - 2.9 7.8 6.1 0.83 9.6 0.1 2.7 3 0 0 3 3 3 0 CDP-archaeol synthase GalKase_gal_bdg PF10509.9 RLN95283.1 - 1.4e-22 79.0 0.2 2.6e-22 78.1 0.2 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 RLN95283.1 - 7.4e-16 58.3 0.3 3.5e-15 56.1 0.3 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 RLN95283.1 - 2.4e-13 50.1 1.2 6.7e-13 48.7 0.8 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain Orn_Arg_deC_N PF02784.16 RLN95284.1 - 5.4e-28 98.0 0.0 7.8e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain ASD2 PF08687.11 RLN95284.1 - 0.11 12.0 0.2 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Sec6 PF06046.13 RLN95284.1 - 0.12 10.8 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 Pkinase_Tyr PF07714.17 RLN95285.1 - 1.7e-45 155.3 0.0 3.4e-44 151.1 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN95285.1 - 1.5e-40 139.2 0.0 2.5e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 RLN95285.1 - 0.12 11.3 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain WW PF00397.26 RLN95286.1 - 3e-11 43.2 0.0 5.3e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 WW domain Methyltr_RsmB-F PF01189.17 RLN95287.1 - 9.6e-33 113.5 0.0 9.3e-31 107.0 0.0 2.5 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 RLN95287.1 - 0.012 15.7 0.0 0.036 14.2 0.0 1.8 1 0 0 1 1 1 0 FtsJ-like methyltransferase SpoIIE PF07228.12 RLN95288.1 - 1.8e-07 31.3 0.2 2.4e-06 27.6 0.1 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 RLN95288.1 - 6.9e-07 29.1 0.4 6.9e-07 29.1 0.4 2.1 1 1 1 2 2 2 1 Protein phosphatase 2C FAD_binding_1 PF00667.20 RLN95289.1 - 3e-58 197.0 0.1 6.4e-58 195.9 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain POR_N PF01855.19 RLN95289.1 - 1.6e-12 47.7 1.0 3.1e-12 46.8 1.0 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg NAD_binding_1 PF00175.21 RLN95289.1 - 5.4e-12 46.3 0.0 3.5e-11 43.7 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain POR PF01558.18 RLN95289.1 - 3.1e-08 33.9 0.3 9.7e-08 32.3 0.3 1.8 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 RLN95289.1 - 4.6e-05 23.7 0.6 0.00024 21.4 0.1 2.5 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II DUF1878 PF08963.10 RLN95289.1 - 0.2 12.2 0.0 0.43 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) Metallophos_3 PF14582.6 RLN95290.1 - 0.058 12.7 0.1 2.8 7.2 0.1 2.4 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily Peptidase_C2 PF00648.21 RLN95291.1 - 5.5e-44 150.4 0.0 1.4e-43 149.1 0.0 1.6 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 RLN95291.1 - 3.7e-17 62.9 0.0 5.5e-07 29.9 0.0 5.4 5 0 0 5 5 5 4 Calpain large subunit, domain III DUF4228 PF14009.6 RLN95291.1 - 0.16 12.3 1.6 0.22 11.9 0.3 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4228) ApbA PF02558.16 RLN95292.1 - 1.4e-12 47.5 0.2 4.9e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 RLN95292.1 - 0.00047 20.4 0.1 0.0012 19.1 0.1 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal F420_oxidored PF03807.17 RLN95292.1 - 0.037 14.6 0.5 1.6 9.4 0.1 2.5 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Myb_DNA-binding PF00249.31 RLN95293.1 - 9.9e-23 80.1 0.7 2.9e-14 53.0 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN95293.1 - 2.5e-15 56.5 0.0 2.5e-13 50.1 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN95293.1 - 0.001 18.9 0.0 2 8.4 0.0 2.4 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 RLN95293.1 - 0.093 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 SLIDE Ribosomal_L11_N PF03946.14 RLN95294.1 - 4.4e-21 74.5 0.6 6.7e-21 73.9 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 RLN95294.1 - 3e-16 59.7 0.1 4.7e-16 59.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF621 PF04789.15 RLN95295.1 - 0.058 12.6 0.8 0.099 11.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF621) Arc PF03869.14 RLN95295.1 - 0.12 12.2 0.1 4.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Arc-like DNA binding domain SIR2 PF02146.17 RLN95296.1 - 1.6e-38 132.4 0.0 1e-37 129.8 0.0 1.9 1 1 0 1 1 1 1 Sir2 family CH PF00307.31 RLN95297.1 - 2e-42 143.8 0.0 2.5e-21 75.9 0.0 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RLN95297.1 - 0.0002 21.1 0.0 0.26 11.1 0.0 2.4 2 0 0 2 2 2 2 CAMSAP CH domain CDC24 PF06395.11 RLN95297.1 - 0.004 17.4 0.1 2.3 8.5 0.0 2.3 2 0 0 2 2 2 2 CDC24 Calponin Anoctamin PF04547.12 RLN95299.1 - 1.8e-88 297.4 5.8 2.2e-88 297.1 5.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel PARP PF00644.20 RLN95300.1 - 2e-39 135.2 0.1 4.4e-34 117.8 0.0 2.9 3 1 0 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain PDEase_I PF00233.19 RLN95301.1 - 1.8e-69 234.1 0.8 3e-69 233.4 0.8 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase UCR_Fe-S_N PF10399.9 RLN95301.1 - 0.69 9.3 0.0 0.69 9.3 0.0 3.1 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal tRNA-synt_2c PF01411.19 RLN95302.1 - 6.1e-204 678.6 0.0 7.9e-204 678.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 RLN95302.1 - 1.3e-15 57.2 0.0 3.8e-15 55.7 0.0 1.9 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 RLN95302.1 - 6.5e-09 36.3 5.8 1.9e-08 34.8 5.8 1.9 1 0 0 1 1 1 1 DHHA1 domain DUF3138 PF11336.8 RLN95303.1 - 0.28 9.7 1.8 0.5 8.9 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) GIT_CC PF16559.5 RLN95303.1 - 1.2 9.1 16.4 1.8 8.5 3.7 3.5 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Fungal_TACC PF12709.7 RLN95303.1 - 2.8 8.5 6.9 17 6.0 0.3 3.3 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins JAKMIP_CC3 PF16034.5 RLN95303.1 - 4.4 7.2 15.7 0.2 11.6 2.2 3.5 2 1 1 3 3 3 0 JAKMIP CC3 domain Ribosom_S12_S23 PF00164.25 RLN95304.1 - 3.9e-49 165.0 0.9 5e-49 164.7 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Hist_deacetyl PF00850.19 RLN95305.1 - 1.3e-79 267.9 0.0 1.8e-79 267.4 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain GST_N_3 PF13417.6 RLN95306.1 - 8.9e-11 42.0 0.0 2.4e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MMR_HSR1 PF01926.23 RLN95306.1 - 9.3e-10 38.6 0.1 0.0021 18.1 0.0 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase GST_N PF02798.20 RLN95306.1 - 2.2e-09 37.5 0.0 5.1e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RLN95306.1 - 7.4e-05 22.9 0.1 0.00018 21.6 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GTP_EFTU PF00009.27 RLN95306.1 - 0.00014 21.4 0.1 2.4 7.7 0.0 3.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RLN95306.1 - 0.00022 21.2 0.1 0.00057 19.8 0.0 1.6 2 0 0 2 2 1 1 RsgA GTPase GST_C_3 PF14497.6 RLN95306.1 - 0.00037 20.6 0.0 0.00098 19.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Dynamin_N PF00350.23 RLN95306.1 - 0.00044 20.4 0.9 0.0023 18.0 0.9 2.1 1 1 0 1 1 1 1 Dynamin family GST_C_2 PF13410.6 RLN95306.1 - 0.0011 18.9 0.0 0.0029 17.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RLN95306.1 - 0.0039 17.4 0.0 0.0086 16.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Spore_IV_A PF09547.10 RLN95306.1 - 0.009 15.0 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Stage IV sporulation protein A (spore_IV_A) AAA_14 PF13173.6 RLN95306.1 - 0.017 15.1 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 RLN95306.1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 RLN95306.1 - 0.033 14.4 0.0 0.85 9.9 0.0 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RLN95306.1 - 0.04 13.5 0.0 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Ras family AAA_16 PF13191.6 RLN95306.1 - 0.045 14.1 0.0 0.086 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 RLN95306.1 - 0.057 13.2 0.0 0.14 11.9 0.0 1.7 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Septin PF00735.18 RLN95306.1 - 0.065 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.9 RLN95306.1 - 0.086 12.6 0.0 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 RLN95306.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein FeoB_N PF02421.18 RLN95306.1 - 0.17 11.4 0.8 3.4 7.2 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B FYVE PF01363.21 RLN95308.1 - 0.00024 21.2 5.9 0.00061 19.9 5.9 1.7 1 0 0 1 1 1 1 FYVE zinc finger zf-B_box PF00643.24 RLN95308.1 - 0.022 14.9 5.0 0.064 13.4 0.4 2.4 2 0 0 2 2 2 0 B-box zinc finger IBR PF01485.21 RLN95308.1 - 0.92 9.8 5.0 0.22 11.7 0.9 2.1 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain FtsJ PF01728.19 RLN95309.1 - 1.4e-34 119.8 0.3 3.9e-33 115.0 0.0 2.0 1 1 1 2 2 2 2 FtsJ-like methyltransferase Phage_int_SAM_5 PF13102.6 RLN95310.1 - 0.00061 20.1 0.1 0.00097 19.4 0.1 1.3 1 0 0 1 1 1 1 Phage integrase SAM-like domain FAM150 PF15129.6 RLN95310.1 - 0.088 13.0 0.6 0.14 12.3 0.6 1.4 1 1 0 1 1 1 0 FAM150 family PX PF00787.24 RLN95311.1 - 1.2e-11 44.6 0.0 2.6e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 PX domain DUF3027 PF11228.8 RLN95311.1 - 0.065 13.3 7.1 1.8 8.6 4.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3027) Collagen PF01391.18 RLN95311.1 - 3.8 7.3 6.8 21 4.9 6.8 2.1 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) DUF4079 PF13301.6 RLN95312.1 - 0.01 16.0 2.1 5.5 7.1 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF4079) Presenilin PF01080.17 RLN95313.1 - 8e-81 271.8 7.6 1.7e-80 270.7 7.6 1.5 1 1 0 1 1 1 1 Presenilin NOT2_3_5 PF04153.18 RLN95315.1 - 8.9e-22 77.6 5.1 4e-21 75.5 5.1 1.9 1 1 0 1 1 1 1 NOT2 / NOT3 / NOT5 family MFS_1 PF07690.16 RLN95316.1 - 2.2e-31 109.1 21.0 2.6e-31 108.9 21.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 RLN95316.1 - 0.00086 18.7 5.4 0.00086 18.7 5.4 1.5 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Spt4 PF06093.13 RLN95316.1 - 0.021 14.9 0.3 0.067 13.3 0.0 1.9 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger MFS_1 PF07690.16 RLN95317.1 - 1e-29 103.6 14.5 1.2e-29 103.4 14.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 RLN95317.1 - 0.00036 19.9 5.4 0.00057 19.3 5.4 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Spt4 PF06093.13 RLN95317.1 - 0.016 15.3 0.3 0.053 13.6 0.0 1.9 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger Phage_holin_3_6 PF07332.11 RLN95317.1 - 3 7.9 10.3 0.52 10.4 0.1 2.6 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III CHB_HEX PF03173.13 RLN95318.1 - 0.11 12.2 0.5 0.2 11.3 0.5 1.5 1 1 0 1 1 1 0 Putative carbohydrate binding domain BT1 PF03092.16 RLN95319.1 - 1.2e-14 53.5 12.6 1.7e-11 43.1 1.4 3.3 2 1 1 3 3 3 3 BT1 family GAF_3 PF13492.6 RLN95320.1 - 0.13 12.6 0.1 21 5.5 0.0 2.8 2 0 0 2 2 2 0 GAF domain Anoctamin PF04547.12 RLN95321.1 - 1.2e-100 337.5 0.8 1.6e-100 337.1 0.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel LRR_4 PF12799.7 RLN95322.1 - 4.3e-26 90.5 5.4 0.062 13.8 0.0 11.6 8 3 3 11 11 11 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RLN95322.1 - 2.1e-06 27.3 33.2 12 6.2 0.0 15.0 14 2 4 18 18 18 2 Leucine Rich repeat LRR_1 PF00560.33 RLN95322.1 - 1.1e-05 25.3 28.4 35 5.5 0.9 13.9 13 2 1 14 14 14 1 Leucine Rich Repeat LRR_8 PF13855.6 RLN95322.1 - 0.003 17.3 9.9 14 5.5 0.1 7.4 5 3 2 7 7 7 2 Leucine rich repeat BT1 PF03092.16 RLN95323.1 - 4.6e-15 54.8 9.0 8.9e-11 40.7 1.3 3.2 3 0 0 3 3 3 3 BT1 family MFS_1 PF07690.16 RLN95323.1 - 7.5e-05 21.8 23.3 7.5e-05 21.8 23.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 RLN95323.1 - 0.00047 19.3 11.2 0.037 13.0 0.3 3.1 3 0 0 3 3 3 3 PUCC protein FYVE_2 PF02318.16 RLN95324.1 - 2.1e-05 24.7 4.4 3.8e-05 23.9 4.4 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger C1_2 PF03107.16 RLN95324.1 - 0.0055 17.0 1.3 0.018 15.3 1.3 2.0 1 0 0 1 1 1 1 C1 domain FYVE PF01363.21 RLN95324.1 - 0.28 11.4 9.7 0.61 10.3 9.7 1.5 1 0 0 1 1 1 0 FYVE zinc finger Pyr_redox_2 PF07992.14 RLN95325.1 - 9.6e-31 107.1 0.6 2.1e-29 102.7 0.6 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 RLN95325.1 - 1.4e-21 76.4 0.3 2.1e-21 75.8 0.3 1.3 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 RLN95325.1 - 1.5e-10 41.1 0.0 3.9e-09 36.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 RLN95325.1 - 1.9e-10 41.1 0.2 9.4e-07 29.3 0.2 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RLN95325.1 - 1e-08 34.8 0.3 0.015 14.6 0.0 4.1 2 1 2 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RLN95325.1 - 1.1e-07 30.9 0.2 2.8e-05 23.0 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.24 RLN95325.1 - 5.5e-07 29.2 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 RLN95325.1 - 1.9e-06 27.5 0.2 1.4e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 RLN95325.1 - 3.5e-06 26.8 2.4 0.0003 20.5 0.1 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 RLN95325.1 - 5.4e-06 25.8 0.8 0.0001 21.5 0.1 3.0 3 1 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 RLN95325.1 - 8.7e-05 21.9 0.1 0.0015 17.9 0.0 2.1 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 RLN95325.1 - 9.5e-05 21.6 0.1 0.0065 15.6 0.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 RLN95325.1 - 0.00017 22.0 0.7 0.33 11.4 0.0 2.7 2 1 0 2 2 2 2 Putative NAD(P)-binding Shikimate_DH PF01488.20 RLN95325.1 - 0.00018 21.6 0.0 0.084 12.9 0.0 2.7 3 0 0 3 3 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 RLN95325.1 - 0.00033 20.0 1.3 0.00054 19.3 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 RLN95325.1 - 0.00048 19.5 0.0 0.17 11.2 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.19 RLN95325.1 - 0.0014 17.1 0.0 0.11 10.9 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Lycopene_cycl PF05834.12 RLN95325.1 - 0.0038 16.3 0.0 0.1 11.6 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein YjeF_N PF03853.15 RLN95325.1 - 0.0074 16.2 0.7 0.11 12.4 0.0 2.3 1 1 1 2 2 2 1 YjeF-related protein N-terminus 2-Hacid_dh_C PF02826.19 RLN95325.1 - 0.027 13.8 0.0 0.63 9.4 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 RLN95325.1 - 0.03 14.3 0.0 0.4 10.7 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 RLN95325.1 - 0.042 13.7 0.1 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 RLN95325.1 - 0.055 13.5 1.9 0.18 11.8 0.0 2.7 3 1 1 4 4 3 0 FAD-NAD(P)-binding TrkA_N PF02254.18 RLN95325.1 - 0.066 13.5 0.0 5.9 7.2 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain AdoHcyase_NAD PF00670.21 RLN95325.1 - 0.087 12.9 1.4 3.5 7.7 0.2 2.4 1 1 1 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 RLN95325.1 - 0.1 12.1 0.1 0.68 9.5 0.1 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 RLN95325.1 - 0.15 12.3 0.1 0.63 10.2 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase FYVE PF01363.21 RLN95326.1 - 0.0023 18.0 15.4 0.0047 17.0 15.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger SIR2 PF02146.17 RLN95326.1 - 0.38 10.7 3.6 3.3 7.6 1.3 3.0 3 1 0 3 3 3 0 Sir2 family FYVE_2 PF02318.16 RLN95326.1 - 5.7 7.2 16.7 0.075 13.2 8.7 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger MFS_1 PF07690.16 RLN95328.1 - 2.8e-24 85.7 44.0 3.4e-23 82.1 21.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN95328.1 - 1.5e-23 83.4 9.9 2e-23 83.0 9.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Ank_2 PF12796.7 RLN95329.1 - 1.3e-15 57.7 0.6 8.6e-11 42.3 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) FYVE PF01363.21 RLN95329.1 - 1.6e-15 57.0 7.5 3e-15 56.1 7.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger Ank_4 PF13637.6 RLN95329.1 - 1.8e-14 53.9 1.1 4.7e-07 30.2 0.1 4.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN95329.1 - 4.3e-10 39.6 1.2 0.0016 18.7 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN95329.1 - 5.3e-10 38.7 0.2 0.34 11.6 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 RLN95329.1 - 2.6e-08 33.9 0.5 0.0008 19.8 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Siva PF05458.12 RLN95329.1 - 0.16 11.6 3.0 0.35 10.5 3.0 1.6 1 0 0 1 1 1 0 Cd27 binding protein (Siva) FYVE_2 PF02318.16 RLN95329.1 - 0.7 10.1 7.4 3.6 7.8 7.4 1.9 1 1 1 2 2 2 0 FYVE-type zinc finger ATP_bind_1 PF03029.17 RLN95330.1 - 2.3e-54 184.7 0.0 3.1e-53 181.0 0.0 2.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein EF-hand_8 PF13833.6 RLN95330.1 - 0.0062 16.4 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair DUF1838 PF08894.11 RLN95330.1 - 0.051 13.3 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1838) Use1 PF09753.9 RLN95330.1 - 0.051 13.3 0.2 0.076 12.7 0.2 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 Beta-lactamase PF00144.24 RLN95331.1 - 7e-36 124.1 0.1 1.2e-35 123.4 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase PKD_channel PF08016.12 RLN95332.1 - 1.2e-23 83.5 12.3 8.2e-17 61.0 12.4 3.2 2 1 1 3 3 3 3 Polycystin cation channel Ion_trans PF00520.31 RLN95332.1 - 2.7e-06 26.8 14.6 1.6e-05 24.3 12.1 2.3 2 1 0 3 3 3 1 Ion transport protein DUF373 PF04123.13 RLN95332.1 - 0.77 9.1 5.0 1.4 8.3 5.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DctQ PF04290.12 RLN95332.1 - 2.2 8.2 17.3 0.13 12.1 7.8 3.1 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Pkinase_Tyr PF07714.17 RLN95333.1 - 7.8e-49 166.3 0.0 7.7e-42 143.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN95333.1 - 2.6e-41 141.7 0.0 2.7e-35 122.0 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Arm PF00514.23 RLN95333.1 - 8.6e-10 38.3 0.8 1.1 9.4 0.0 7.4 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN95333.1 - 0.00012 22.4 11.8 0.45 10.9 0.2 5.1 3 2 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 RLN95333.1 - 0.0096 16.4 7.2 0.56 10.8 0.2 3.9 4 0 0 4 4 4 2 HEAT-like repeat Pkinase_fungal PF17667.1 RLN95333.1 - 0.093 11.5 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 RLN95333.1 - 0.14 11.8 0.0 2.7 7.5 0.0 2.6 3 0 0 3 3 3 0 RIO1 family HEAT PF02985.22 RLN95333.1 - 0.14 12.5 0.1 45 4.7 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat STPPase_N PF16891.5 RLN95334.1 - 0.0036 17.7 0.2 0.0068 16.8 0.2 1.5 1 1 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain zf-CCCH PF00642.24 RLN95336.1 - 4.8e-13 48.6 34.6 6.3e-05 22.8 3.5 4.3 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 RLN95336.1 - 2.8e-10 40.8 16.7 0.052 14.2 0.1 4.4 3 1 1 4 4 4 4 Torus domain zf_CCCH_4 PF18345.1 RLN95336.1 - 5.6e-08 32.6 42.9 0.013 15.6 2.6 4.4 4 0 0 4 4 4 4 Zinc finger domain VWA_2 PF13519.6 RLN95336.1 - 2.7e-07 31.2 0.0 8.2e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 RLN95336.1 - 3.9e-06 27.2 0.0 6.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-CCCH_4 PF18044.1 RLN95336.1 - 0.0018 18.0 32.7 0.0095 15.7 2.3 4.3 4 0 0 4 4 4 3 CCCH-type zinc finger BBP1_C PF15272.6 RLN95336.1 - 0.053 13.3 0.7 12 5.6 0.0 3.4 2 1 0 3 3 3 0 Spindle pole body component BBP1, C-terminal PKcGMP_CC PF16808.5 RLN95336.1 - 0.15 12.0 11.0 0.59 10.0 0.3 4.2 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase zf-CCCH_3 PF15663.5 RLN95336.1 - 5.9 7.1 15.0 99 3.2 6.3 4.2 3 1 0 3 3 3 0 Zinc-finger containing family ABC_tran_CTD PF16326.5 RLN95336.1 - 9.5 6.6 37.3 5.5 7.3 5.3 6.5 5 2 1 6 6 6 0 ABC transporter C-terminal domain GAIN PF16489.5 RLN95337.1 - 0.002 17.6 1.5 0.0043 16.5 1.5 1.6 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain ThylakoidFormat PF11264.8 RLN95337.1 - 3.6 7.2 18.3 0.78 9.4 12.3 2.6 1 1 1 2 2 2 0 Thylakoid formation protein LicD PF04991.13 RLN95337.1 - 5 7.2 16.3 1.1 9.3 10.3 2.0 1 1 0 2 2 2 0 LicD family WD40 PF00400.32 RLN95338.1 - 1.4e-15 57.4 3.7 0.0014 19.4 0.2 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN95338.1 - 5.4e-07 29.8 4.6 0.0037 17.5 0.1 3.4 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Uso1_p115_C PF04871.13 RLN95339.1 - 0.0011 19.3 14.6 0.0011 19.3 14.6 13.6 4 1 9 13 13 13 5 Uso1 / p115 like vesicle tethering protein, C terminal region HrpB7 PF09486.10 RLN95339.1 - 0.0044 17.4 20.8 0.0044 17.4 20.8 12.8 5 3 7 12 12 12 2 Bacterial type III secretion protein (HrpB7) FYVE PF01363.21 RLN95341.1 - 6.7e-11 42.2 13.4 1.5e-10 41.1 13.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger INCENP_ARK-bind PF03941.15 RLN95342.1 - 4.2e-10 39.4 0.3 4.2e-10 39.4 0.3 2.5 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Transthyretin PF00576.21 RLN95343.1 - 4.8e-37 127.0 0.2 6e-37 126.7 0.2 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family Methyltransf_25 PF13649.6 RLN95344.1 - 2.4e-12 47.4 0.0 5.2e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN95344.1 - 9.8e-11 42.2 0.2 2.4e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN95344.1 - 2.1e-09 37.5 0.0 3.2e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN95344.1 - 2.4e-07 31.4 0.0 4.3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN95344.1 - 9.5e-07 28.4 0.0 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 RLN95344.1 - 2.7e-06 27.2 0.1 5.3e-06 26.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 RLN95344.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_20 PF12147.8 RLN95344.1 - 0.059 12.5 0.0 0.078 12.1 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_28 PF02636.17 RLN95344.1 - 0.068 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF444 PF04285.12 RLN95345.1 - 2.2 7.3 7.0 0.78 8.7 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF444) DUF563 PF04577.14 RLN95346.1 - 3.6e-31 108.9 0.0 6.6e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) HTH_21 PF13276.6 RLN95346.1 - 0.24 11.5 2.0 5.9 7.1 0.1 2.6 2 0 0 2 2 2 0 HTH-like domain Mannosyl_trans3 PF11051.8 RLN95347.1 - 5e-34 117.9 0.0 7.5e-33 114.1 0.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.8 RLN95348.1 - 2e-34 119.2 0.0 6.1e-22 78.3 0.0 2.2 2 0 0 2 2 2 2 Mannosyltransferase putative Afi1 PF07792.12 RLN95349.1 - 0.13 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Pim PF16765.5 RLN95349.1 - 0.14 12.3 0.0 1 9.6 0.0 2.1 1 1 1 2 2 2 0 Pesticin immunity protein GST_N_3 PF13417.6 RLN95350.1 - 8.6e-17 61.3 0.0 1.7e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN95350.1 - 1.2e-13 51.1 0.0 2.9e-13 49.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RLN95350.1 - 6.8e-13 48.8 0.0 1.4e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RLN95350.1 - 7.5e-07 29.3 0.1 1.1e-06 28.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RLN95350.1 - 9.4e-05 22.4 0.0 0.00026 20.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RLN95350.1 - 0.00047 20.3 0.1 0.00091 19.4 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 RLN95350.1 - 0.02 15.2 0.1 0.044 14.1 0.0 1.6 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein HSF_DNA-bind PF00447.17 RLN95351.1 - 1.5e-24 86.5 0.8 2.9e-24 85.5 0.8 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding ATG16 PF08614.11 RLN95351.1 - 0.019 15.2 2.5 0.038 14.2 2.5 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TEX13 PF15186.6 RLN95351.1 - 0.044 13.5 1.4 0.072 12.8 1.4 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Nsp1_C PF05064.13 RLN95351.1 - 0.079 12.8 1.6 0.15 11.8 1.6 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region tRNA-synt_2 PF00152.20 RLN95352.1 - 4.6e-65 219.8 0.0 1.3e-64 218.3 0.0 1.6 1 1 1 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RLN95352.1 - 1.8e-09 37.4 0.0 4.1e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 RLN95352.1 - 0.0025 17.3 0.0 0.028 13.9 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) DUF3151 PF11349.8 RLN95352.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3151) Pkinase PF00069.25 RLN95353.1 - 2.9e-07 30.1 0.0 1.9e-06 27.5 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Arm PF00514.23 RLN95353.1 - 6.6e-07 29.2 0.7 0.0016 18.4 0.0 3.6 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 RLN95353.1 - 0.4 10.7 7.2 1.6 8.8 0.0 4.6 3 1 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain MatE PF01554.18 RLN95355.1 - 5.4e-34 117.2 25.0 3.9e-22 78.6 10.0 2.1 2 0 0 2 2 2 2 MatE DUF3464 PF11947.8 RLN95355.1 - 0.07 12.9 4.2 1.5 8.6 0.8 2.7 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Mg_trans_NIPA PF05653.14 RLN95356.1 - 2.8e-20 72.6 13.8 4.1e-20 72.1 13.8 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA PLDc_2 PF13091.6 RLN95356.1 - 4.2e-10 39.6 0.0 0.00017 21.5 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 RLN95356.1 - 0.00035 20.6 0.1 0.66 10.3 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif EamA PF00892.20 RLN95356.1 - 0.0085 16.3 5.8 0.0085 16.3 5.8 4.0 3 1 1 4 4 4 1 EamA-like transporter family eIF3_subunit PF08597.10 RLN95356.1 - 0.013 15.5 0.2 0.021 14.8 0.2 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit TFCD_C PF12612.8 RLN95357.1 - 4.2e-53 180.0 0.1 2.9e-51 174.0 0.0 2.9 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 RLN95357.1 - 1.2e-08 34.5 11.7 0.19 12.1 0.0 8.3 9 0 0 9 9 8 2 HEAT repeat TPR_12 PF13424.6 RLN95357.1 - 1.5e-07 31.6 6.2 1.3e-06 28.6 0.7 3.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN95357.1 - 3.2e-07 30.0 7.2 1.4e-06 28.0 0.5 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN95357.1 - 6.8e-05 23.4 2.1 0.0005 20.7 2.1 2.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN95357.1 - 0.00063 20.4 6.6 0.15 13.0 0.4 4.4 2 1 1 3 3 3 1 Tetratricopeptide repeat HEAT_2 PF13646.6 RLN95357.1 - 0.001 19.4 17.2 0.47 10.9 0.2 6.8 7 1 0 7 7 6 1 HEAT repeats HEAT_EZ PF13513.6 RLN95357.1 - 0.0017 18.8 26.0 1.3 9.6 1.7 8.2 7 2 1 8 8 8 2 HEAT-like repeat TPR_7 PF13176.6 RLN95357.1 - 0.0032 17.4 0.9 0.3 11.2 0.1 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN95357.1 - 0.0054 16.5 0.4 0.1 12.5 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN95357.1 - 0.036 14.6 3.7 0.23 12.0 2.5 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 RLN95357.1 - 0.045 13.4 0.1 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.17 RLN95357.1 - 0.11 12.7 0.1 0.11 12.7 0.1 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat HEAT_PBS PF03130.16 RLN95357.1 - 0.16 12.7 10.1 22 6.1 0.0 6.1 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat PH PF00169.29 RLN95358.1 - 4.1e-13 49.7 0.0 1e-12 48.5 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN95358.1 - 0.11 12.8 0.0 0.33 11.3 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 RLN95358.1 - 0.15 12.5 4.4 0.082 13.3 0.4 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain ATAD4 PF15321.6 RLN95358.1 - 3.8 8.9 6.2 3.1 9.2 1.0 3.1 2 1 0 2 2 2 0 ATPase family AAA domain containing 4 kleA_kleC PF17383.2 RLN95359.1 - 0.31 11.4 4.4 0.5 10.7 1.5 2.5 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A Atg14 PF10186.9 RLN95359.1 - 0.92 8.5 6.7 1.4 7.9 6.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NPV_P10 PF05531.12 RLN95359.1 - 2 9.0 4.3 7.5 7.1 0.3 2.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein PRP21_like_P PF12230.8 RLN95360.1 - 0.015 15.2 10.6 0.017 15.0 10.6 1.0 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein RNA_pol_Rpc4 PF05132.14 RLN95360.1 - 1.5 9.3 5.6 1.5 9.3 5.6 1.0 1 0 0 1 1 1 0 RNA polymerase III RPC4 TRAP_alpha PF03896.16 RLN95360.1 - 7.2 5.7 9.3 6.9 5.8 9.3 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF5375 PF17345.2 RLN95363.1 - 0.027 14.3 0.0 0.079 12.8 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5375) 3-alpha PF03475.14 RLN95363.1 - 0.046 13.6 0.6 0.16 11.8 0.3 2.1 2 0 0 2 2 2 0 3-alpha domain EF-hand_1 PF00036.32 RLN95364.1 - 1.7e-06 27.1 0.4 0.00032 20.0 0.1 3.0 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RLN95364.1 - 1.9e-05 25.0 8.4 3.1e-05 24.3 3.3 3.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 RLN95364.1 - 0.00029 20.6 3.4 0.047 13.5 0.1 3.1 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN95364.1 - 0.00049 19.5 6.4 0.0053 16.2 0.2 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RLN95364.1 - 0.00052 19.7 11.9 0.00088 19.0 0.2 3.7 3 0 0 3 3 3 2 EF-hand domain DnaB_2 PF07261.11 RLN95366.1 - 0.062 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Replication initiation and membrane attachment His_Phos_2 PF00328.22 RLN95367.1 - 8.7e-22 78.0 0.0 1.1e-21 77.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ferric_reduct PF01794.19 RLN95368.1 - 1.6e-18 67.0 10.1 1.6e-18 67.0 10.1 2.7 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 RLN95368.1 - 4e-12 46.2 0.0 1e-11 44.8 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 RLN95368.1 - 1.5e-09 38.2 0.0 1.6e-08 34.8 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NopRA1 PF16201.5 RLN95369.1 - 5.4e-48 163.3 0.2 5.4e-48 163.3 0.2 3.1 4 0 0 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 Npa1 PF11707.8 RLN95369.1 - 4.7e-25 88.7 0.7 1e-24 87.6 0.0 2.0 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal Img2 PF05046.14 RLN95369.1 - 0.17 12.2 0.0 0.71 10.2 0.0 2.1 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) Pur_ac_phosph_N PF16656.5 RLN95370.1 - 1.7e-18 67.0 0.0 3.2e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 RLN95370.1 - 9.9e-16 58.8 2.2 1.9e-15 57.9 2.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 RLN95370.1 - 1.1e-11 45.4 0.8 2.5e-11 44.3 0.3 1.9 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Prominin PF05478.11 RLN95371.1 - 0.038 11.9 3.9 0.066 11.2 3.9 1.3 1 0 0 1 1 1 0 Prominin WD40 PF00400.32 RLN95371.1 - 0.088 13.7 0.3 2.5 9.1 0.0 3.6 5 0 0 5 5 5 0 WD domain, G-beta repeat Pro_isomerase PF00160.21 RLN95372.1 - 1.8e-09 38.1 0.0 3.8e-06 27.2 0.0 2.1 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Spc7 PF08317.11 RLN95373.1 - 0.0032 16.4 29.3 0.0032 16.4 29.3 3.1 2 1 1 3 3 3 1 Spc7 kinetochore protein PI_PP_I PF18363.1 RLN95373.1 - 0.11 12.7 7.3 3.7 7.8 0.0 3.1 2 1 0 2 2 2 0 Phosphoinositide phosphatase insertion domain DUF2935 PF11155.8 RLN95373.1 - 0.14 12.5 10.2 2.1 8.7 2.9 3.7 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF2321 PF10083.9 RLN95373.1 - 4.1 7.0 8.7 5.6 6.6 4.3 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Pkinase PF00069.25 RLN95374.1 - 5.7e-50 170.1 0.0 7.9e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN95374.1 - 6.8e-13 48.5 0.0 1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase F-box-like PF12937.7 RLN95374.1 - 1.3e-07 31.4 0.3 2.8e-06 27.1 0.2 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 RLN95374.1 - 0.031 14.2 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 F-box domain Kdo PF06293.14 RLN95374.1 - 0.033 13.5 0.0 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cyclin_N PF00134.23 RLN95375.1 - 3.6e-23 81.7 4.0 1.5e-22 79.7 1.5 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 RLN95375.1 - 2.4e-22 79.3 0.3 3.9e-22 78.6 0.3 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain AAA_5 PF07728.14 RLN95376.1 - 1.2e-31 109.6 0.0 1.6e-17 63.8 0.0 3.7 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 RLN95376.1 - 4.3e-15 55.8 0.2 7.1e-14 51.9 0.0 2.8 3 0 0 3 3 2 1 Midasin AAA lid domain AAA_7 PF12775.7 RLN95376.1 - 6e-12 45.5 0.0 9.4e-06 25.3 0.1 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_6 PF12774.7 RLN95376.1 - 1.7e-08 33.8 0.1 0.00012 21.2 0.0 2.8 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region AAA_16 PF13191.6 RLN95376.1 - 2.2e-08 34.7 5.1 0.0029 18.0 0.0 4.2 4 2 0 4 4 4 2 AAA ATPase domain AAA PF00004.29 RLN95376.1 - 4.8e-07 30.3 0.2 0.012 16.1 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RLN95376.1 - 2.1e-06 27.6 0.0 0.069 12.9 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Viral_helicase1 PF01443.18 RLN95376.1 - 3.3e-06 27.0 0.2 0.0087 15.8 0.0 2.7 3 0 0 3 3 2 2 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 RLN95376.1 - 1e-05 24.9 0.2 0.025 13.8 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.6 RLN95376.1 - 1.4e-05 25.5 0.6 0.05 13.9 0.1 2.8 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 RLN95376.1 - 1.5e-05 25.3 0.0 0.067 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 RLN95376.1 - 1.8e-05 24.8 0.2 0.24 11.3 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain TsaE PF02367.17 RLN95376.1 - 5.1e-05 23.3 0.2 0.022 14.8 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 RLN95376.1 - 6e-05 23.1 0.0 0.72 9.9 0.0 4.1 4 0 0 4 4 4 1 AAA domain Dynein_heavy PF03028.15 RLN95376.1 - 6.3e-05 23.0 0.0 0.26 11.4 0.0 2.9 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain AAA_3 PF07726.11 RLN95376.1 - 0.00014 21.8 0.0 0.014 15.3 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RLN95376.1 - 0.00018 22.1 0.0 0.3 11.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 RLN95376.1 - 0.00026 21.1 0.1 1.5 8.9 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain NACHT PF05729.12 RLN95376.1 - 0.0003 20.8 0.1 0.33 10.9 0.1 2.8 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.27 RLN95376.1 - 0.00056 20.4 0.7 0.064 13.8 0.2 3.0 2 1 0 2 2 2 1 ABC transporter RNA_helicase PF00910.22 RLN95376.1 - 0.00057 20.3 0.0 0.088 13.2 0.0 2.7 2 0 0 2 2 2 1 RNA helicase RsgA_GTPase PF03193.16 RLN95376.1 - 0.00091 19.2 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 RLN95376.1 - 0.0013 18.4 3.4 0.2 11.2 0.1 3.3 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.9 RLN95376.1 - 0.0019 18.0 0.0 0.067 12.9 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation tRNA_lig_kinase PF08303.11 RLN95376.1 - 0.0019 18.3 0.1 0.082 13.0 0.0 2.5 2 0 0 2 2 2 1 tRNA ligase kinase domain AAA_28 PF13521.6 RLN95376.1 - 0.0026 18.0 2.2 2 8.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain SRP54 PF00448.22 RLN95376.1 - 0.0042 16.7 0.1 2.3 7.8 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 RLN95376.1 - 0.0074 16.2 0.0 2.6 7.9 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_23 PF13476.6 RLN95376.1 - 0.012 16.1 0.1 0.047 14.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain DUF853 PF05872.12 RLN95376.1 - 0.014 14.0 0.1 1.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) ATP-synt_ab PF00006.25 RLN95376.1 - 0.023 14.3 0.1 1.7 8.3 0.0 2.9 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.13 RLN95376.1 - 0.027 13.6 0.6 2.8 7.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF815) CbiA PF01656.23 RLN95376.1 - 0.028 14.5 0.5 4.7 7.3 0.0 2.8 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Mg_chelatase PF01078.21 RLN95376.1 - 0.037 13.4 0.2 5.8 6.2 0.1 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI UvrD-helicase PF00580.21 RLN95376.1 - 0.044 13.3 0.1 2.9 7.3 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_33 PF13671.6 RLN95376.1 - 0.047 13.8 0.2 8 6.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain TniB PF05621.11 RLN95376.1 - 0.054 12.9 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 RLN95376.1 - 0.055 13.2 0.1 7.6 6.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 RLN95376.1 - 0.057 13.2 0.1 0.6 9.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 RLN95376.1 - 0.064 13.0 0.2 0.23 11.2 0.0 2.0 2 0 0 2 2 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 RLN95376.1 - 0.073 12.4 1.8 7.8 5.8 0.1 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family PRK PF00485.18 RLN95376.1 - 0.087 12.6 0.6 7.9 6.2 0.0 2.6 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 RLN95376.1 - 0.092 11.9 0.0 5.6 6.0 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit WD40 PF00400.32 RLN95377.1 - 2.1e-14 53.7 5.1 0.0025 18.6 0.1 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN95377.1 - 2.7e-07 30.8 0.8 0.0022 18.3 0.5 4.3 3 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN95377.1 - 1.5e-06 27.2 3.3 3.7e-05 22.6 1.1 2.6 1 1 2 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 RLN95377.1 - 0.026 14.4 0.1 0.26 11.1 0.1 2.4 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A CALM_bind PF16025.5 RLN95377.1 - 5.8 7.5 13.6 0.88 10.1 4.6 3.1 3 0 0 3 3 3 0 Calcium-dependent calmodulin binding Penicil_amidase PF01804.18 RLN95378.1 - 0.081 11.9 6.1 0.096 11.6 6.1 1.2 1 0 0 1 1 1 0 Penicillin amidase NYD-SP28_assoc PF14775.6 RLN95378.1 - 0.52 10.5 8.1 5.4 7.2 1.7 2.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain Prefoldin_2 PF01920.20 RLN95379.1 - 1.1e-18 67.1 0.8 1.1e-18 67.1 0.8 2.7 3 0 0 3 3 3 1 Prefoldin subunit zf-Tim10_DDP PF02953.15 RLN95379.1 - 1.8e-16 59.5 1.5 4.5e-16 58.2 1.5 1.7 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DASH_Dad3 PF08656.10 RLN95379.1 - 0.015 15.4 0.3 0.015 15.4 0.3 2.6 3 1 0 3 3 3 0 DASH complex subunit Dad3 DinB_2 PF12867.7 RLN95379.1 - 0.082 13.4 1.0 15 6.1 0.1 3.0 2 1 1 3 3 3 0 DinB superfamily DUF4795 PF16043.5 RLN95379.1 - 0.52 9.9 8.8 8.2 6.0 2.1 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4795) GAT PF03127.14 RLN95379.1 - 0.95 9.8 12.4 2.5 8.5 2.0 3.9 3 1 1 4 4 4 0 GAT domain DUF1664 PF07889.12 RLN95379.1 - 1.2 9.2 7.9 0.36 10.9 2.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF5082 PF16888.5 RLN95379.1 - 2.2 8.6 7.3 0.42 10.9 1.4 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) Cmc1 PF08583.10 RLN95380.1 - 3.3e-09 36.6 2.2 4.7e-09 36.1 2.1 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 RLN95380.1 - 0.1 12.8 1.3 0.17 12.1 1.3 1.4 1 0 0 1 1 1 0 CHCH domain Ubiq_cyt_C_chap PF03981.12 RLN95381.1 - 6.3e-23 81.4 0.3 6.3e-23 81.4 0.3 1.5 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone WW PF00397.26 RLN95381.1 - 4e-05 23.6 0.2 7.2e-05 22.8 0.2 1.4 1 0 0 1 1 1 1 WW domain ETC_C1_NDUFA5 PF04716.14 RLN95382.1 - 4.9e-15 55.1 0.4 3e-07 30.2 0.0 2.5 2 0 0 2 2 2 2 ETC complex I subunit conserved region CIDE-N PF02017.15 RLN95382.1 - 0.023 14.7 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 CIDE-N domain Sas10 PF09368.10 RLN95383.1 - 4.5e-26 91.1 11.2 4.5e-26 91.1 11.2 2.4 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 RLN95383.1 - 7.3e-09 36.1 2.1 7.3e-09 36.1 2.1 2.8 2 1 0 2 2 2 1 Sas10/Utp3/C1D family DEPP PF15343.6 RLN95383.1 - 0.092 12.8 6.9 0.048 13.7 3.9 1.9 1 1 1 2 2 2 0 Decidual protein induced by progesterone family Nop PF01798.18 RLN95384.1 - 6.3e-85 284.3 0.1 6.3e-85 284.3 0.1 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin RNA_polI_A34 PF08208.11 RLN95384.1 - 0.047 13.8 36.3 0.082 13.0 36.3 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF4604 PF15377.6 RLN95384.1 - 0.56 10.6 31.0 1 9.8 31.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) GAGA_bind PF06217.12 RLN95384.1 - 0.62 10.3 13.8 0.83 9.9 13.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 RLN95384.1 - 0.62 9.8 22.8 0.87 9.4 22.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 RLN95384.1 - 4.2 6.1 10.8 5.2 5.7 10.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Acylphosphatase PF00708.18 RLN95385.1 - 4.3e-12 46.3 0.1 6.2e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 Acylphosphatase DUF2012 PF09430.10 RLN95386.1 - 4.3e-22 78.5 0.0 7e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 RLN95386.1 - 0.0011 19.1 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF2846 PF11008.8 RLN95386.1 - 0.015 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) SdrD_B PF17210.3 RLN95386.1 - 0.089 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 SdrD B-like domain Lar_N PF09861.9 RLN95387.1 - 1.8e-08 33.8 0.0 6.1e-08 32.1 0.0 1.8 1 1 0 1 1 1 1 Lactate racemase N-terminal domain CX9C PF16860.5 RLN95388.1 - 0.48 10.5 3.8 1.7 8.7 0.3 2.4 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, ABC2_membrane PF01061.24 RLN95393.1 - 2.1e-64 216.8 59.7 2.8e-35 121.7 25.5 3.0 4 0 0 4 4 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN95393.1 - 4.2e-35 121.2 0.2 1.7e-16 61.0 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 RLN95393.1 - 3.2e-10 39.8 0.1 3.2e-10 39.8 0.1 3.4 3 1 0 3 3 2 1 CDR ABC transporter RsgA_GTPase PF03193.16 RLN95393.1 - 1.1e-07 32.0 0.7 0.0045 16.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 RLN95393.1 - 6.6e-07 29.4 0.0 0.56 10.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN95393.1 - 1.3e-06 28.9 0.1 0.0059 17.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.7 RLN95393.1 - 5.3e-06 25.8 14.2 5.3e-06 25.8 14.2 3.5 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_29 PF13555.6 RLN95393.1 - 2.2e-05 24.1 7.7 0.023 14.4 1.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN95393.1 - 3.5e-05 24.1 0.1 0.16 12.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 RLN95393.1 - 6.1e-05 22.7 0.0 0.13 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 RLN95393.1 - 0.00015 21.3 2.1 0.86 9.0 0.2 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RLN95393.1 - 0.0002 21.9 0.9 0.58 10.6 0.4 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 RLN95393.1 - 0.00055 19.7 0.1 1.2 8.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN95393.1 - 0.00079 18.8 0.9 0.088 12.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.23 RLN95393.1 - 0.0013 18.8 1.3 0.27 11.3 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 RLN95393.1 - 0.0023 18.1 0.6 0.35 11.1 0.1 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 RLN95393.1 - 0.0024 18.3 0.4 5.4 7.5 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RLN95393.1 - 0.0063 17.1 0.1 3.1 8.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 RLN95393.1 - 0.0086 16.0 1.3 4.5 7.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.17 RLN95393.1 - 0.011 15.8 3.4 0.42 10.7 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Ploopntkinase3 PF18751.1 RLN95393.1 - 0.013 15.4 0.3 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_5 PF07728.14 RLN95393.1 - 0.015 15.3 0.4 0.46 10.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.19 RLN95393.1 - 0.019 14.6 1.7 0.91 9.1 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 RLN95393.1 - 0.019 15.3 0.5 2.6 8.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ATPase_2 PF01637.18 RLN95393.1 - 0.024 14.6 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ABC_ATPase PF09818.9 RLN95393.1 - 0.027 13.3 0.6 1.2 7.8 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_19 PF13245.6 RLN95393.1 - 0.038 14.3 0.1 8.2 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RLN95393.1 - 0.054 13.2 0.4 11 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 RLN95393.1 - 0.1 12.5 0.1 6.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_33 PF13671.6 RLN95393.1 - 0.11 12.6 0.1 8 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 RLN95393.1 - 0.14 12.1 4.8 1.8 8.5 0.2 3.3 3 0 0 3 3 3 0 NTPase Gtr1_RagA PF04670.12 RLN95393.1 - 0.15 11.4 1.1 6.4 6.1 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 RLN95393.1 - 0.18 11.8 0.3 3 7.9 0.0 2.3 2 0 0 2 2 2 0 Dynamin family DUF2075 PF09848.9 RLN95393.1 - 0.18 11.0 0.2 0.9 8.7 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PduV-EutP PF10662.9 RLN95393.1 - 0.24 11.1 1.9 4 7.2 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase PF06745.13 RLN95393.1 - 0.34 10.2 1.6 5.7 6.2 0.1 2.5 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.6 RLN95393.1 - 0.35 11.1 1.8 22 5.3 0.8 2.4 2 0 0 2 2 2 0 AAA domain Abhydrolase_6 PF12697.7 RLN95394.1 - 1.1e-08 36.0 0.0 1.4e-08 35.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN95394.1 - 0.00024 20.5 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Telomerase_RBD PF12009.8 RLN95395.1 - 1.1e-05 25.6 0.2 2.9e-05 24.2 0.2 1.7 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 RLN95396.1 - 1.2e-15 57.6 0.0 2.2e-11 43.7 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) ABC_tran PF00005.27 RLN95397.1 - 2.9e-12 47.3 0.2 6.3e-12 46.2 0.0 1.6 2 0 0 2 2 2 1 ABC transporter Cir_N PF10197.9 RLN95397.1 - 2.5e-07 30.8 12.2 5.7e-07 29.6 12.2 1.7 1 0 0 1 1 1 1 N-terminal domain of CBF1 interacting co-repressor CIR AAA_16 PF13191.6 RLN95397.1 - 0.00049 20.5 0.8 0.00064 20.2 0.1 1.6 2 1 0 2 2 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 RLN95397.1 - 0.0045 16.9 0.3 0.0069 16.3 0.2 1.4 1 1 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 RLN95397.1 - 0.0051 16.1 0.0 0.0096 15.2 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 RLN95397.1 - 0.0056 16.4 0.6 0.013 15.3 0.6 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN95397.1 - 0.0087 16.3 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 RLN95397.1 - 0.011 15.8 1.1 0.36 10.9 0.1 2.2 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.17 RLN95397.1 - 0.012 15.7 0.7 0.065 13.3 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain Ploopntkinase3 PF18751.1 RLN95397.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 MMR_HSR1 PF01926.23 RLN95397.1 - 0.018 15.1 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Roc PF08477.13 RLN95397.1 - 0.022 15.0 0.1 0.045 14.0 0.1 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 RLN95397.1 - 0.026 14.5 0.1 0.069 13.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 RLN95397.1 - 0.068 12.9 0.3 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 RLN95397.1 - 0.077 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 RLN95397.1 - 0.094 12.6 0.2 0.16 11.9 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 RLN95397.1 - 0.097 11.9 0.1 0.097 11.9 0.1 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 RLN95397.1 - 0.099 12.2 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RLN95397.1 - 0.11 13.1 0.2 0.43 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 RLN95397.1 - 0.12 12.3 0.2 0.23 11.3 0.2 1.5 1 0 0 1 1 1 0 NTPase Ras PF00071.22 RLN95397.1 - 0.16 11.5 1.0 0.87 9.2 0.0 2.0 2 0 0 2 2 2 0 Ras family RNA_helicase PF00910.22 RLN95397.1 - 0.19 12.1 0.0 0.35 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase CWC25 PF12542.8 RLN95397.1 - 0.2 12.6 0.0 0.2 12.6 0.0 2.4 2 1 1 3 3 2 0 Pre-mRNA splicing factor AAA_23 PF13476.6 RLN95397.1 - 0.4 11.2 5.7 0.4 11.1 0.1 2.4 2 1 0 2 2 2 0 AAA domain zf-C4H2 PF10146.9 RLN95399.1 - 0.17 12.2 1.9 19 5.5 1.4 3.2 2 1 0 2 2 2 0 Zinc finger-containing protein Filament PF00038.21 RLN95399.1 - 0.31 10.6 19.4 0.2 11.2 0.1 3.0 2 1 1 3 3 3 0 Intermediate filament protein BNIP3 PF06553.12 RLN95400.1 - 2.3 7.9 8.5 1.1 8.9 4.1 2.1 1 1 1 2 2 2 0 BNIP3 HSF_DNA-bind PF00447.17 RLN95402.1 - 1.1e-21 77.2 1.4 1.6e-21 76.7 1.4 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding PAP2_C PF14360.6 RLN95403.1 - 3.4e-19 69.1 4.5 3.4e-19 69.1 4.5 3.0 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 RLN95403.1 - 9.8e-06 25.4 2.5 9.8e-06 25.4 2.5 2.3 2 1 0 2 2 2 1 PAP2 superfamily YtpI PF14007.6 RLN95403.1 - 0.066 13.4 0.4 0.066 13.4 0.4 2.4 3 0 0 3 3 3 0 YtpI-like protein Aa_trans PF01490.18 RLN95404.1 - 1.8e-36 125.7 0.0 2.4e-31 108.8 0.0 2.5 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein Ras PF00071.22 RLN95404.1 - 4.2e-17 62.2 0.0 6.6e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN95404.1 - 1.5e-09 38.1 0.0 3.8e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SH2 PF00017.24 RLN95404.1 - 0.001 19.1 0.0 0.0027 17.8 0.0 1.7 1 0 0 1 1 1 1 SH2 domain BRCT PF00533.26 RLN95405.1 - 1.6e-05 25.2 0.0 2e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 RLN95405.1 - 0.00014 21.8 0.0 0.00016 21.5 0.0 1.1 1 0 0 1 1 1 1 twin BRCT domain bZIP_1 PF00170.21 RLN95406.1 - 3.3e-08 33.5 15.3 6.3e-08 32.6 15.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RLN95406.1 - 3e-06 27.2 12.8 9.9e-06 25.6 12.8 1.9 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 RLN95406.1 - 0.00033 21.1 10.4 0.00095 19.6 10.4 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor FapA PF03961.13 RLN95406.1 - 0.0068 15.1 1.0 0.0092 14.6 1.0 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A V_ATPase_I PF01496.19 RLN95406.1 - 0.27 9.1 3.4 0.38 8.6 3.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Csm1_N PF18504.1 RLN95406.1 - 0.3 11.5 8.4 0.41 11.0 3.8 2.9 3 0 0 3 3 3 0 Csm1 N-terminal domain HIP1_clath_bdg PF16515.5 RLN95406.1 - 0.51 11.0 18.8 8.4 7.1 12.4 3.6 2 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YabA PF06156.13 RLN95406.1 - 1.2 9.8 5.1 2.7 8.7 2.7 2.5 2 1 1 3 3 3 0 Initiation control protein YabA Seryl_tRNA_N PF02403.22 RLN95406.1 - 1.7 8.9 10.2 3.5 7.9 8.2 2.4 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 RLN95406.1 - 3 8.0 5.7 6.5 6.9 4.7 2.0 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family AAA_25 PF13481.6 RLN95407.1 - 0.0036 16.9 0.2 0.016 14.8 0.0 2.1 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.7 RLN95407.1 - 0.056 12.3 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Ras PF00071.22 RLN95407.1 - 0.086 12.4 0.1 1 8.9 0.0 2.2 2 0 0 2 2 2 0 Ras family CbiA PF01656.23 RLN95407.1 - 0.12 12.4 0.0 0.4 10.7 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Chordopox_A20R PF05941.13 RLN95407.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A20R protein Ras PF00071.22 RLN95409.1 - 5.1e-52 175.7 0.0 6.2e-52 175.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN95409.1 - 7.8e-32 110.0 0.0 1.1e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN95409.1 - 1.7e-10 40.7 0.0 2.1e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RLN95409.1 - 0.00015 21.2 0.0 0.00019 20.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 RLN95409.1 - 0.0018 17.8 0.0 0.0069 15.8 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 RLN95409.1 - 0.045 13.3 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RLN95409.1 - 0.065 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 RLN95409.1 - 0.14 12.5 1.0 0.57 10.5 0.9 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 RLN95409.1 - 0.16 12.0 0.1 0.47 10.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain Vezatin PF12632.7 RLN95410.1 - 5.4e-06 26.0 0.0 1.3e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes Cation_efflux PF01545.21 RLN95410.1 - 0.054 13.2 2.5 0.1 12.3 2.5 1.4 1 0 0 1 1 1 0 Cation efflux family Mob1_phocein PF03637.17 RLN95412.1 - 1.4e-59 200.9 0.0 1.9e-59 200.5 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family WW PF00397.26 RLN95413.1 - 4.1e-06 26.8 1.9 8.7e-06 25.7 1.9 1.6 1 0 0 1 1 1 1 WW domain FAIM1 PF06905.13 RLN95413.1 - 0.009 15.7 0.3 0.019 14.7 0.1 1.6 2 0 0 2 2 2 1 Fas apoptotic inhibitory molecule (FAIM1) Clathrin_lg_ch PF01086.17 RLN95414.1 - 0.039 14.0 1.3 0.063 13.3 0.6 1.6 2 0 0 2 2 2 0 Clathrin light chain DUF3978 PF13123.6 RLN95414.1 - 0.083 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3978) bZIP_1 PF00170.21 RLN95414.1 - 0.16 12.1 1.9 0.32 11.1 1.9 1.4 1 0 0 1 1 1 0 bZIP transcription factor TetR_C_6 PF13977.6 RLN95414.1 - 0.37 11.0 3.2 2.2 8.5 0.2 2.3 1 1 1 2 2 2 0 BetI-type transcriptional repressor, C-terminal DUF1057 PF06342.12 RLN95415.1 - 7.4e-18 64.6 0.0 1e-16 60.8 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_6 PF12697.7 RLN95415.1 - 1.1e-12 49.1 0.3 1.9e-12 48.3 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN95415.1 - 6e-12 45.3 0.0 9.9e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN95415.1 - 9e-12 45.2 0.2 2.8e-11 43.6 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 RLN95415.1 - 0.0011 18.8 0.0 0.0022 17.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 RLN95415.1 - 0.005 17.0 0.0 0.013 15.7 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.13 RLN95415.1 - 0.029 14.2 0.1 0.097 12.5 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase PGAP1 PF07819.13 RLN95415.1 - 0.073 12.8 0.0 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_5 PF12695.7 RLN95415.1 - 0.13 12.0 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 RLN95415.1 - 0.17 11.4 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 RLN95416.1 - 2e-15 58.0 3.9 2.6e-15 57.6 3.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 RLN95416.1 - 1.9e-12 46.8 0.0 5.1e-12 45.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_1 PF00561.20 RLN95416.1 - 1.1e-11 44.8 0.1 3.4e-07 30.2 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN95416.1 - 6.6e-09 35.4 0.4 4.5e-08 32.7 0.3 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 RLN95416.1 - 2e-05 24.3 0.0 9.3e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 RLN95416.1 - 2.1e-05 24.4 1.1 0.15 11.9 0.0 3.6 2 2 2 4 4 4 2 Serine hydrolase Thioesterase PF00975.20 RLN95416.1 - 0.0002 21.6 0.2 0.00035 20.8 0.2 1.4 1 0 0 1 1 1 1 Thioesterase domain Protoglobin PF11563.8 RLN95416.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.6 1 1 0 1 1 1 0 Protoglobin PGAP1 PF07819.13 RLN95416.1 - 0.021 14.5 0.2 0.29 10.8 0.2 2.1 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.13 RLN95416.1 - 0.032 14.1 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 RLN95416.1 - 0.086 12.7 0.0 0.21 11.4 0.1 1.6 2 0 0 2 2 2 0 Lipase (class 3) PAF-AH_p_II PF03403.13 RLN95416.1 - 0.26 9.7 0.0 0.39 9.2 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 RLN95417.1 - 5.4e-18 66.4 1.2 5.4e-18 66.4 1.2 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN95417.1 - 9.8e-16 58.2 0.0 3e-12 46.7 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF1057 PF06342.12 RLN95417.1 - 3.3e-12 46.0 0.0 1.9e-11 43.6 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Hydrolase_4 PF12146.8 RLN95417.1 - 6.5e-08 32.1 0.1 8.1e-07 28.5 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 RLN95417.1 - 0.0022 17.6 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 RLN95417.1 - 0.008 16.0 0.1 0.033 14.0 0.1 2.0 2 0 0 2 2 2 1 Serine hydrolase Thioesterase PF00975.20 RLN95417.1 - 0.034 14.2 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_6 PF12697.7 RLN95418.1 - 1.2e-15 58.7 2.8 1.9e-15 58.1 2.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 RLN95418.1 - 5e-13 48.7 0.0 1.7e-12 47.0 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_1 PF00561.20 RLN95418.1 - 1.9e-11 44.1 0.0 7.1e-07 29.1 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN95418.1 - 6.3e-09 35.4 0.0 1.3e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 RLN95418.1 - 1.3e-05 25.5 0.0 7.8e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Thioesterase domain LIDHydrolase PF10230.9 RLN95418.1 - 0.00061 19.4 0.0 0.021 14.4 0.0 2.1 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 RLN95418.1 - 0.0016 18.3 0.4 0.56 10.1 0.1 2.2 2 0 0 2 2 2 2 Serine hydrolase FSH1 PF03959.13 RLN95418.1 - 0.031 13.9 0.0 0.097 12.3 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) PGAP1 PF07819.13 RLN95418.1 - 0.11 12.2 0.0 4.4 7.0 0.0 2.4 3 0 0 3 3 3 0 PGAP1-like protein Lipase_3 PF01764.25 RLN95418.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DDE_1 PF03184.19 RLN95419.1 - 1.9e-31 109.1 0.1 2.9e-31 108.5 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_ABP1_N PF18107.1 RLN95419.1 - 1.9e-08 33.9 0.0 5.2e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 RLN95419.1 - 1.2e-06 28.4 0.1 5.4e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 RLN95419.1 - 0.0012 18.6 0.0 0.0035 17.1 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease NAM-associated PF14303.6 RLN95420.1 - 0.91 10.2 12.5 2.7 8.7 12.5 1.7 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Glyco_hydro_18 PF00704.28 RLN95421.1 - 6.9e-21 75.3 1.0 1.3e-19 71.1 0.2 2.0 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 TEX29 PF15839.5 RLN95421.1 - 0.0013 19.3 0.2 0.0037 17.8 0.2 1.7 1 0 0 1 1 1 1 Testis-expressed sequence 29 protein ODV-E18 PF10717.9 RLN95421.1 - 0.92 9.4 4.4 0.33 10.9 1.0 2.1 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 MIOX PF05153.15 RLN95422.1 - 3.6e-42 144.6 0.0 5.5e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Myo-inositol oxygenase Acetyltransf_1 PF00583.25 RLN95422.1 - 2.4e-05 24.5 0.0 0.00018 21.8 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Fascin PF06268.13 RLN95422.1 - 0.0001 22.5 0.0 0.026 14.8 0.0 2.4 1 1 1 2 2 2 2 Fascin domain Acetyltransf_7 PF13508.7 RLN95422.1 - 0.0003 21.1 0.0 0.00094 19.6 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RLN95422.1 - 0.00047 20.1 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 RLN95422.1 - 0.0016 18.5 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FRG1 PF06229.12 RLN95422.1 - 0.018 14.8 0.0 0.62 9.8 0.0 2.3 1 1 1 2 2 2 0 FRG1-like domain DUF569 PF04601.13 RLN95422.1 - 0.087 12.5 0.0 4.2 7.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF569) FR47 PF08445.10 RLN95422.1 - 0.17 11.9 0.1 0.36 10.8 0.1 1.5 1 0 0 1 1 1 0 FR47-like protein Pkinase PF00069.25 RLN95424.1 - 2.3e-47 161.6 0.0 3.1e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN95424.1 - 6.9e-46 156.6 0.0 9.2e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN95424.1 - 0.084 12.8 1.1 0.55 10.1 0.2 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family RT_RNaseH PF17917.1 RLN95424.1 - 0.13 12.6 0.0 0.9 9.9 0.0 2.2 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Pkinase_Tyr PF07714.17 RLN95425.1 - 6.6e-46 156.7 0.0 8.6e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN95425.1 - 1.1e-43 149.5 0.0 1.5e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 RLN95425.1 - 0.0037 17.2 0.4 0.0037 17.2 0.4 2.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN95425.1 - 0.047 13.0 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RLN95425.1 - 0.14 11.0 0.1 0.31 10.0 0.1 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 RLN95425.1 - 0.21 10.3 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF4381 PF14316.6 RLN95425.1 - 0.64 10.3 5.5 7.8 6.7 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) cNMP_binding PF00027.29 RLN95426.1 - 1e-33 115.3 5.4 3.6e-10 39.8 0.0 6.2 4 2 1 5 5 5 5 Cyclic nucleotide-binding domain Aminotran_3 PF00202.21 RLN95427.1 - 2.7e-50 171.2 0.0 1e-48 166.1 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.6 RLN95427.1 - 5.4e-19 68.8 0.0 9.6e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain VATC PF18716.1 RLN95428.1 - 2.1e-17 62.7 3.9 4e-17 61.8 3.9 1.5 1 0 0 1 1 1 1 Vms1-associating treble clef domain PTE PF02126.18 RLN95428.1 - 4.1e-07 29.7 0.0 0.00026 20.5 0.0 2.7 2 1 0 2 2 2 2 Phosphotriesterase family Myosin_head PF00063.21 RLN95429.1 - 7.6e-213 708.5 0.4 1.3e-212 707.8 0.4 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 RLN95429.1 - 4.1e-31 108.1 0.4 4.1e-31 108.1 0.4 1.9 2 0 0 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding AAA_22 PF13401.6 RLN95429.1 - 0.0013 19.0 0.2 0.073 13.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 RLN95429.1 - 0.0042 17.4 0.0 0.015 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain YjeJ PF15922.5 RLN95429.1 - 0.023 14.0 0.5 0.55 9.4 0.2 2.3 2 0 0 2 2 2 0 YjeJ-like AAA_16 PF13191.6 RLN95429.1 - 0.028 14.8 0.1 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ATPase PF06745.13 RLN95429.1 - 0.085 12.2 0.1 9.8 5.4 0.0 2.6 2 0 0 2 2 2 0 KaiC ResIII PF04851.15 RLN95429.1 - 0.11 12.4 0.1 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit FH2 PF02181.23 RLN95430.1 - 1.5e-37 129.6 0.9 1.5e-37 129.6 0.9 2.6 2 1 0 2 2 2 1 Formin Homology 2 Domain CCDC53 PF10152.9 RLN95430.1 - 1.1e-11 45.4 1.5 5.4e-06 26.9 0.1 3.2 3 0 0 3 3 3 2 Subunit CCDC53 of WASH complex PYC_OADA PF02436.18 RLN95431.1 - 2.6e-17 63.2 0.0 3.8e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_lipoyl PF00364.22 RLN95431.1 - 3e-16 59.0 3.6 5.7e-16 58.1 3.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 RLN95431.1 - 3.3e-10 39.6 1.1 0.00049 19.9 0.2 2.7 2 1 1 3 3 3 2 Biotin-lipoyl like HlyD_3 PF13437.6 RLN95431.1 - 7e-06 26.7 0.6 0.04 14.6 0.0 2.6 3 0 0 3 3 3 2 HlyD family secretion protein NQRA PF05896.11 RLN95431.1 - 4.9e-05 22.9 0.5 6.6e-05 22.5 0.5 1.2 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_D23 PF16576.5 RLN95431.1 - 0.00045 19.5 0.3 0.027 13.7 0.1 2.2 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 RLN95431.1 - 0.0066 16.4 1.0 0.013 15.5 0.9 1.6 1 1 0 1 1 1 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 RLN95431.1 - 0.014 15.2 0.9 0.038 13.9 0.4 1.9 1 1 1 2 2 2 0 Glycine cleavage H-protein IncD PF17628.2 RLN95431.1 - 0.085 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Inclusion membrane protein D PYNP_C PF07831.13 RLN95431.1 - 0.15 11.7 1.1 2.9 7.6 0.0 3.1 3 0 0 3 3 3 0 Pyrimidine nucleoside phosphorylase C-terminal domain DUF2118 PF09891.9 RLN95431.1 - 0.16 11.9 2.4 0.43 10.5 0.2 2.4 2 2 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2118) Toxin_17 PF08086.11 RLN95432.1 - 0.13 12.5 1.8 0.27 11.6 1.8 1.4 1 0 0 1 1 1 0 Ergtoxin family Cation_ATPase_C PF00689.21 RLN95433.1 - 3.4e-43 147.5 0.1 3.4e-43 147.5 0.1 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 RLN95433.1 - 4.8e-39 133.8 1.8 4.8e-39 133.8 1.8 3.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 RLN95433.1 - 3.2e-18 66.8 1.5 2e-14 54.4 1.5 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN95433.1 - 7.8e-17 61.1 0.0 1.4e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 RLN95433.1 - 2.4e-12 46.4 0.0 5.1e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RLN95433.1 - 6.1e-06 26.2 0.3 0.00097 18.9 0.5 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase TPR_2 PF07719.17 RLN95434.1 - 4e-16 57.7 1.8 0.00013 21.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN95434.1 - 9.1e-15 53.8 2.7 0.0014 18.4 1.4 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN95434.1 - 1.4e-10 40.5 6.9 0.0017 18.4 0.0 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN95434.1 - 2.4e-10 39.9 3.4 0.0011 18.6 1.6 3.4 2 1 1 3 3 3 3 TPR repeat TPR_16 PF13432.6 RLN95434.1 - 6e-09 36.4 0.4 0.0013 19.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat FKBP_C PF00254.28 RLN95434.1 - 2e-08 34.4 0.0 3.9e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_19 PF14559.6 RLN95434.1 - 3.2e-08 33.9 2.5 0.00073 20.0 0.1 3.0 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN95434.1 - 2.5e-07 31.0 0.6 0.018 15.9 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN95434.1 - 5.1e-07 29.9 1.9 0.003 17.8 0.1 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN95434.1 - 5.2e-05 23.2 8.3 0.035 14.2 0.3 3.6 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 RLN95434.1 - 0.00019 21.2 0.8 0.19 11.8 0.3 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN95434.1 - 0.00053 20.2 1.2 2.3 8.8 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN95434.1 - 0.00061 19.6 5.2 0.65 10.0 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN95434.1 - 0.0069 16.6 2.5 1.5 9.1 0.0 2.6 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 RLN95434.1 - 0.0099 15.9 0.7 0.0099 15.9 0.7 2.5 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 RLN95434.1 - 0.024 15.2 4.7 3.3 8.6 0.1 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 RLN95434.1 - 0.032 13.7 1.5 0.25 10.8 0.2 2.5 2 0 0 2 2 2 0 SHNi-TPR TPR_9 PF13371.6 RLN95434.1 - 0.04 14.1 0.1 0.44 10.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat SNAP PF14938.6 RLN95434.1 - 0.042 13.3 5.1 0.062 12.7 5.1 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP Death PF00531.22 RLN95434.1 - 0.16 12.2 1.1 1 9.6 0.2 2.2 2 0 0 2 2 2 0 Death domain DUF2225 PF09986.9 RLN95434.1 - 0.38 10.4 4.8 0.63 9.7 4.7 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Alkyl_sulf_dimr PF14863.6 RLN95434.1 - 3.5 8.1 5.7 12 6.3 0.3 2.4 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation PPR_2 PF13041.6 RLN95436.1 - 2.2e-15 56.5 3.1 0.11 12.7 0.0 8.4 4 2 5 9 9 9 4 PPR repeat family PPR_long PF17177.4 RLN95436.1 - 4.3e-14 52.4 8.8 1.2e-07 31.3 0.7 3.1 1 1 2 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 RLN95436.1 - 2.3e-12 46.8 6.1 0.038 14.1 0.0 7.7 3 3 5 9 9 9 4 Pentatricopeptide repeat domain PPR PF01535.20 RLN95436.1 - 1.5e-10 40.6 0.6 3.2 8.2 0.0 8.6 9 0 0 9 9 9 2 PPR repeat TPR_19 PF14559.6 RLN95436.1 - 0.035 14.6 6.4 0.84 10.2 0.2 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat Utp13 PF08625.11 RLN95436.1 - 0.045 13.7 4.0 0.74 9.7 0.1 2.8 3 0 0 3 3 3 0 Utp13 specific WD40 associated domain TPR_14 PF13428.6 RLN95436.1 - 0.055 14.3 9.9 0.46 11.4 0.0 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat Ribosomal_L22 PF00237.19 RLN95436.1 - 0.06 13.6 0.0 8.6 6.7 0.0 3.3 2 1 0 2 2 2 0 Ribosomal protein L22p/L17e HrpB1_HrpK PF09613.10 RLN95436.1 - 0.5 10.0 3.8 0.9 9.2 0.2 2.9 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) PPR_2 PF13041.6 RLN95437.1 - 2.1e-23 82.2 1.4 0.01 16.0 0.0 8.8 4 2 5 9 9 9 5 PPR repeat family PPR_3 PF13812.6 RLN95437.1 - 8.9e-19 67.3 9.5 0.00021 21.3 0.1 7.8 4 2 4 9 9 9 6 Pentatricopeptide repeat domain PPR_long PF17177.4 RLN95437.1 - 1.5e-14 53.9 2.5 5.4e-07 29.2 0.2 4.6 1 1 3 5 5 5 4 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 RLN95437.1 - 1.2e-11 44.0 2.0 1.3 9.4 0.0 9.1 11 0 0 11 11 11 1 PPR repeat RPM2 PF08579.11 RLN95437.1 - 0.0078 16.6 0.2 12 6.4 0.1 4.0 4 1 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) PPR_1 PF12854.7 RLN95437.1 - 0.02 14.6 0.0 1.3 8.8 0.0 3.6 3 0 0 3 3 3 0 PPR repeat FWWh PF14922.6 RLN95437.1 - 0.038 13.9 0.1 0.074 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function ADH_N PF08240.12 RLN95438.1 - 2.3e-26 91.8 3.0 4e-26 91.0 3.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN95438.1 - 2.8e-18 66.1 0.9 4.3e-18 65.5 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN95438.1 - 9.9e-06 26.6 0.0 1.7e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RLN95438.1 - 0.0007 19.0 0.5 0.0024 17.3 0.1 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RLN95438.1 - 0.0019 17.5 0.9 0.0032 16.8 0.9 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain KR PF08659.10 RLN95438.1 - 0.076 12.9 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 KR domain GFO_IDH_MocA PF01408.22 RLN95438.1 - 0.085 13.7 0.1 0.21 12.4 0.1 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 RLN95438.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_N PF08240.12 RLN95439.1 - 3.4e-26 91.3 2.1 3.4e-26 91.3 2.1 1.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN95439.1 - 3.7e-21 75.5 0.1 6.2e-21 74.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN95439.1 - 1.8e-07 32.3 0.0 2.9e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 RLN95439.1 - 7.8e-05 22.1 0.1 0.00013 21.4 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 RLN95439.1 - 0.00015 21.1 0.1 0.00025 20.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 RLN95439.1 - 0.074 13.9 0.1 0.26 12.1 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 RLN95439.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase WD40 PF00400.32 RLN95440.1 - 3.5e-12 46.6 0.8 0.0041 17.9 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat Ribonucleas_3_3 PF14622.6 RLN95441.1 - 1e-21 77.4 0.4 8.3e-21 74.5 0.0 2.4 2 0 0 2 2 2 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 RLN95441.1 - 4.7e-17 62.5 0.1 2.7e-16 60.1 0.0 2.3 2 1 0 2 2 2 1 Ribonuclease III domain SF-assemblin PF06705.11 RLN95441.1 - 1.2e-05 24.8 6.5 1.2e-05 24.8 6.5 2.2 2 0 0 2 2 2 1 SF-assemblin/beta giardin DUF4148 PF13663.6 RLN95441.1 - 0.069 13.3 2.2 6 7.1 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) PIF1 PF05970.14 RLN95442.1 - 2.7e-42 145.3 0.0 3.2e-38 131.8 0.0 2.1 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 RLN95442.1 - 2.4e-22 79.6 0.0 4.3e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RLN95442.1 - 3.2e-08 34.0 0.0 6.7e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RLN95442.1 - 6.8e-06 26.4 0.1 1.9e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 RLN95442.1 - 1.3e-05 24.9 0.0 3.1e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 RLN95442.1 - 0.00013 22.4 0.2 0.00038 20.9 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain PhoH PF02562.16 RLN95442.1 - 0.0038 16.7 0.1 0.01 15.3 0.1 1.7 2 0 0 2 2 2 1 PhoH-like protein AAA_7 PF12775.7 RLN95442.1 - 0.0056 16.2 0.1 0.011 15.3 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Viral_helicase1 PF01443.18 RLN95442.1 - 0.0063 16.3 0.1 0.38 10.5 0.2 2.8 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.14 RLN95442.1 - 0.0067 14.4 0.1 0.086 10.8 0.0 2.0 2 0 0 2 2 2 1 Helicase IstB_IS21 PF01695.17 RLN95442.1 - 0.011 15.4 0.5 0.07 12.8 0.1 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF815 PF05673.13 RLN95442.1 - 0.011 14.9 0.1 0.021 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 RLN95442.1 - 0.013 15.5 0.1 1.7 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 RLN95442.1 - 0.019 14.5 0.2 0.12 11.9 0.0 2.0 1 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 RLN95442.1 - 0.022 14.0 0.0 0.82 8.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 RLN95442.1 - 0.042 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase DEAD PF00270.29 RLN95442.1 - 0.043 13.6 0.0 2.8 7.7 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase Mg_chelatase PF01078.21 RLN95442.1 - 0.072 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI GBP PF02263.19 RLN95442.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 RLN95442.1 - 0.16 12.0 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Microtub_bd PF16796.5 RLN95442.1 - 0.18 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Microtubule binding TsaE PF02367.17 RLN95442.1 - 0.2 11.7 0.3 0.43 10.6 0.3 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 RLN95442.1 - 0.2 11.0 0.1 1.7 8.0 0.0 2.0 2 0 0 2 2 2 0 KaiC Hyr1 PF15789.5 RLN95443.1 - 9 5.9 8.2 24 4.6 0.3 2.5 2 0 0 2 2 2 0 Hyphally regulated cell wall GPI-anchored protein 1 Dynamin_M PF01031.20 RLN95444.1 - 3e-32 112.0 0.0 1.1e-23 83.8 0.0 2.1 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 RLN95444.1 - 0.0023 18.0 0.2 0.005 16.9 0.2 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 RLN95444.1 - 0.015 15.4 0.0 0.042 13.9 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Runt PF00853.19 RLN95444.1 - 0.023 14.3 0.0 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Runt domain HTH_Tnp_Mu_2 PF09039.11 RLN95444.1 - 0.064 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain Hemopexin PF00045.19 RLN95444.1 - 0.081 12.9 0.1 15 5.7 0.0 2.5 2 0 0 2 2 2 0 Hemopexin ABC_tran PF00005.27 RLN95444.1 - 0.089 13.3 0.1 0.17 12.4 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 RLN95444.1 - 0.13 12.0 0.1 0.32 10.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SIS PF01380.22 RLN95446.1 - 1.1e-17 64.1 0.1 2.2e-17 63.1 0.1 1.5 1 1 0 1 1 1 1 SIS domain Pkinase_Tyr PF07714.17 RLN95448.1 - 5.8e-50 170.0 0.0 6.9e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN95448.1 - 2.3e-48 164.9 0.0 2.8e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 RLN95448.1 - 0.0052 16.2 0.0 0.0079 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RLN95448.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Syndecan PF01034.20 RLN95448.1 - 0.02 14.8 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Phage_T7_Capsid PF05396.11 RLN95448.1 - 0.16 12.3 0.0 0.74 10.2 0.0 1.9 2 0 0 2 2 2 0 Phage T7 capsid assembly protein Glyco_hydro_18 PF00704.28 RLN95449.1 - 4.5e-13 49.6 0.0 5.5e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4471 PF14740.6 RLN95450.1 - 4.1e-26 91.9 5.6 1.3e-14 54.2 5.3 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4471) DUF4470 PF14737.6 RLN95450.1 - 5.1e-22 77.9 0.0 1.3e-21 76.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) FYVE PF01363.21 RLN95451.1 - 0.00011 22.2 2.2 0.00018 21.6 2.2 1.3 1 0 0 1 1 1 1 FYVE zinc finger Dus PF01207.17 RLN95454.1 - 1.8e-33 115.9 0.0 2.6e-20 72.7 0.0 2.5 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 RLN95454.1 - 3.3e-09 36.4 7.7 0.00028 20.7 0.3 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 RLN95454.1 - 1.8e-05 24.4 0.3 1.8e-05 24.4 0.3 3.5 4 0 0 4 4 4 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 RLN95454.1 - 5.7e-05 23.0 8.1 0.048 13.7 0.9 3.0 2 0 0 2 2 2 2 Zinc finger domain Lustrin_cystein PF14625.6 RLN95454.1 - 0.099 13.0 0.1 0.56 10.6 0.0 2.2 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain zf-CCCH_2 PF14608.6 RLN95454.1 - 0.78 10.3 6.4 2.1 8.9 0.9 2.7 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 RLN95454.1 - 4.3 8.1 7.5 4.5 8.0 0.1 2.8 1 1 1 2 2 2 0 Torus domain CSTF_C PF14304.6 RLN95455.1 - 0.008 15.7 1.4 0.018 14.6 1.4 1.6 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal WW PF00397.26 RLN95456.1 - 7.5e-09 35.5 3.6 3.9e-07 30.0 0.1 2.8 2 0 0 2 2 2 2 WW domain IQ PF00612.27 RLN95456.1 - 0.0035 17.0 1.2 0.0035 17.0 1.2 11.9 11 0 0 11 11 11 6 IQ calmodulin-binding motif zf-B_box PF00643.24 RLN95456.1 - 0.45 10.7 20.1 0.081 13.1 2.8 4.4 4 0 0 4 4 4 0 B-box zinc finger Ebp2 PF05890.12 RLN95457.1 - 6.7e-11 42.3 20.4 7.5e-11 42.1 20.4 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 PAP_assoc PF03828.19 RLN95458.1 - 3e-16 59.4 0.3 8.2e-16 58.0 0.3 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 RLN95458.1 - 1.3e-05 25.4 0.0 3.2e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Glyco_transf_22 PF03901.17 RLN95459.1 - 7.9e-67 226.3 16.4 7.2e-44 150.7 2.3 3.0 2 1 1 3 3 3 3 Alg9-like mannosyltransferase family PMT_2 PF13231.6 RLN95459.1 - 1.8 8.7 12.7 0.32 11.2 7.7 2.3 2 1 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase RRM_1 PF00076.22 RLN95460.1 - 0.0023 17.7 0.0 0.0046 16.8 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SHR-BD PF06650.12 RLN95461.1 - 3.3e-39 134.9 0.1 1.1e-31 110.2 0.0 4.2 5 0 0 5 5 5 3 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 RLN95461.1 - 2.5e-13 50.2 0.1 1e-12 48.2 0.1 2.1 1 1 0 1 1 1 1 N-terminal region of Chorein or VPS13 PH PF00169.29 RLN95461.1 - 2.8e-07 31.0 0.1 0.001 19.6 0.0 3.0 2 0 0 2 2 2 2 PH domain DEP PF00610.21 RLN95461.1 - 0.00021 21.2 0.0 0.004 17.2 0.0 2.5 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) C2 PF00168.30 RLN95461.1 - 0.052 13.8 0.0 0.27 11.5 0.0 2.4 2 0 0 2 2 2 0 C2 domain A2L_zn_ribbon PF08792.10 RLN95461.1 - 0.74 9.6 3.5 17 5.3 0.1 3.5 3 0 0 3 3 3 0 A2L zinc ribbon domain VPS13_C PF16909.5 RLN95462.1 - 1.8e-55 187.5 0.9 6.8e-51 172.6 0.1 2.8 2 1 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal PH PF00169.29 RLN95462.1 - 3.4e-09 37.1 0.0 1.1e-08 35.5 0.0 1.9 1 0 0 1 1 1 1 PH domain ATG_C PF09333.11 RLN95462.1 - 2.3e-07 31.1 0.1 2.5e-06 27.7 0.0 2.6 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain PDZ_6 PF17820.1 RLN95462.1 - 0.0068 16.2 0.1 0.018 14.9 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RLN95462.1 - 0.017 15.4 0.0 0.042 14.2 0.0 1.6 1 0 0 1 1 1 0 PDZ domain zf-BED PF02892.15 RLN95463.1 - 0.0041 17.1 0.1 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 BED zinc finger Dimer_Tnp_hAT PF05699.14 RLN95463.1 - 0.005 16.6 0.0 0.027 14.3 0.0 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4674 PF15719.5 RLN95463.1 - 0.81 9.7 6.7 1.5 8.8 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) DER1 PF04511.15 RLN95464.1 - 1.3e-16 61.1 4.1 1.4e-16 61.0 4.1 1.0 1 0 0 1 1 1 1 Der1-like family Atg14 PF10186.9 RLN95465.1 - 1.9e-20 73.2 0.0 2.2e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 APG6 PF04111.12 RLN95465.1 - 0.0053 16.7 0.0 0.0066 16.4 0.0 1.1 1 0 0 1 1 1 1 Apg6 BARA domain RNA_pol_A_bac PF01000.26 RLN95466.1 - 8.4e-24 84.1 0.1 2.9e-22 79.2 0.0 3.0 2 2 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 RLN95466.1 - 7.8e-13 47.7 0.0 1e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_7 PF12838.7 RLN95466.1 - 0.018 15.6 2.5 0.018 15.6 2.5 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Pkinase PF00069.25 RLN95470.1 - 1.9e-61 207.7 0.0 3.3e-61 207.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN95470.1 - 7.7e-33 113.9 0.0 1.5e-32 112.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN95470.1 - 3.5e-09 36.4 0.0 6.2e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN95470.1 - 5.5e-06 25.9 0.0 1.5e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RLN95470.1 - 0.00068 19.3 0.7 0.0019 17.9 0.0 2.0 2 0 0 2 2 2 1 RIO1 family DUF3417 PF11897.8 RLN95470.1 - 6.2 7.3 7.9 15 6.1 4.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) IF-2B PF01008.17 RLN95471.1 - 8.9e-45 153.1 0.8 1.2e-44 152.6 0.8 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family TBPIP_N PF15517.6 RLN95471.1 - 0.1 12.6 0.5 7.3 6.7 0.1 2.3 1 1 1 2 2 2 0 TBP-interacting protein N-terminus YTH PF04146.15 RLN95472.1 - 2.6e-22 79.5 0.0 4.8e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain Dev_Cell_Death PF10539.9 RLN95472.1 - 1.5e-18 66.9 0.0 2.4e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Development and cell death domain zf-CCCH PF00642.24 RLN95472.1 - 1.6e-15 56.5 22.7 6.5e-09 35.5 1.6 3.9 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RLN95472.1 - 7.5e-13 48.1 39.0 1.6e-06 28.0 4.2 5.3 5 0 0 5 5 5 3 Zinc finger domain zf-CCCH_2 PF14608.6 RLN95472.1 - 3.6e-09 36.7 29.5 0.0006 20.2 0.4 4.8 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 RLN95472.1 - 6.4e-08 32.2 31.7 0.00015 21.5 0.8 4.6 3 1 1 4 4 4 3 CCCH-type zinc finger Torus PF16131.5 RLN95472.1 - 1.5e-06 28.9 18.1 0.005 17.5 1.1 3.4 2 1 1 3 3 3 3 Torus domain KH_1 PF00013.29 RLN95472.1 - 0.001 18.8 0.1 0.0025 17.6 0.1 1.6 1 0 0 1 1 1 1 KH domain zf-CCCH_3 PF15663.5 RLN95472.1 - 0.015 15.5 15.0 0.019 15.1 2.5 3.3 1 1 1 3 3 3 0 Zinc-finger containing family PRP4 PF08799.11 RLN95473.1 - 1.6e-10 40.3 5.5 3.4e-10 39.3 5.5 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Prp18 PF02840.15 RLN95473.1 - 1.9e-07 31.2 0.0 1.9e-07 31.2 0.0 2.1 2 1 0 2 2 2 1 Prp18 domain CHDNT PF08073.12 RLN95473.1 - 0.32 11.0 1.0 0.77 9.8 0.3 1.9 2 0 0 2 2 2 0 CHDNT (NUC034) domain Pex14_N PF04695.13 RLN95473.1 - 0.64 10.7 8.1 0.12 13.0 4.4 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5423 PF17461.2 RLN95473.1 - 1.1 8.0 8.1 1.9 7.2 8.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Spore_coat_CotO PF14153.6 RLN95473.1 - 1.3 8.9 17.0 0.22 11.4 13.1 1.6 2 0 0 2 2 2 0 Spore coat protein CotO Ndc1_Nup PF09531.10 RLN95473.1 - 3.7 6.1 5.2 4.8 5.8 5.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sec6 PF06046.13 RLN95474.1 - 5.8e-21 74.5 4.7 9e-21 73.9 4.7 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 DUF4239 PF14023.6 RLN95474.1 - 1.8 8.2 5.7 9.6 5.9 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4239) Aida_C2 PF14186.6 RLN95475.1 - 5.4e-39 133.1 1.5 3.4e-30 104.6 0.8 2.1 1 1 1 2 2 2 2 Cytoskeletal adhesion DUF748 PF05359.11 RLN95475.1 - 0.059 13.5 0.0 0.08 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF748) PX PF00787.24 RLN95476.1 - 1e-09 38.4 0.5 2.7e-09 37.0 0.5 1.7 1 0 0 1 1 1 1 PX domain Sld5 PF05916.11 RLN95477.1 - 3.5e-17 62.8 0.1 5.2e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 GINS complex protein TIMELESS PF04821.14 RLN95477.1 - 0.00036 19.9 0.0 0.00075 18.9 0.0 1.5 1 1 1 2 2 2 1 Timeless protein DUF1677 PF07911.13 RLN95478.1 - 0.0037 17.6 1.2 0.0037 17.6 1.2 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1677) AP3D1 PF06375.11 RLN95478.1 - 0.014 15.6 10.1 0.017 15.3 10.1 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Mucin PF01456.17 RLN95478.1 - 0.063 13.3 4.2 0.083 12.9 4.2 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Coilin_N PF15862.5 RLN95478.1 - 3.3 7.5 15.0 1.6 8.5 13.1 1.4 1 1 0 1 1 1 0 Coilin N-terminus RRM_1 PF00076.22 RLN95479.1 - 1.2e-32 111.6 0.2 5.6e-16 58.1 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 RLN95479.1 - 4.4e-30 103.0 39.4 1.8e-06 27.7 1.5 5.5 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RLN95479.1 - 1.2e-25 88.8 64.6 1.9e-06 27.7 5.8 5.4 5 0 0 5 5 5 5 Zinc finger domain zf-CCCH_4 PF18044.1 RLN95479.1 - 4.2e-22 77.5 43.4 5.2e-06 26.1 1.9 5.5 5 0 0 5 5 5 5 CCCH-type zinc finger Torus PF16131.5 RLN95479.1 - 1.6e-14 54.5 42.3 9.8e-05 23.0 0.4 6.6 4 2 3 7 7 6 5 Torus domain zf-CCCH_3 PF15663.5 RLN95479.1 - 2.5e-08 34.1 17.8 0.19 12.0 0.1 5.5 4 1 1 5 5 5 4 Zinc-finger containing family RRM_7 PF16367.5 RLN95479.1 - 1.2e-07 31.8 0.1 0.00098 19.2 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif RNA_polI_A34 PF08208.11 RLN95479.1 - 0.00038 20.6 20.5 0.00038 20.6 20.5 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 zf-CCCH_2 PF14608.6 RLN95479.1 - 0.016 15.6 50.1 0.036 14.6 4.1 5.4 5 0 0 5 5 5 0 RNA-binding, Nab2-type zinc finger RRM_8 PF11835.8 RLN95479.1 - 0.038 14.2 0.0 0.08 13.2 0.0 1.5 1 0 0 1 1 1 0 RRM-like domain Med19 PF10278.9 RLN95479.1 - 1.1 9.2 28.2 2.1 8.3 28.2 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF2052 PF09747.9 RLN95479.1 - 2.1 8.4 17.5 1.5 8.9 11.8 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) GAGA_bind PF06217.12 RLN95479.1 - 2.5 8.3 13.6 0.81 9.9 9.8 2.0 2 0 0 2 2 2 0 GAGA binding protein-like family Connexin PF00029.19 RLN95479.1 - 7.7 6.2 9.8 16 5.1 9.8 1.5 1 0 0 1 1 1 0 Connexin DUSP PF06337.12 RLN95480.1 - 1.8e-08 34.9 0.0 3.6e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 DUSP domain DUF4820 PF16091.5 RLN95480.1 - 0.076 12.4 0.3 0.13 11.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Cellulose_synt PF03552.14 RLN95480.1 - 0.13 10.7 1.5 0.18 10.3 1.5 1.1 1 0 0 1 1 1 0 Cellulose synthase Adeno_PV PF03910.13 RLN95480.1 - 0.57 8.8 4.9 1.3 7.6 4.9 1.5 1 0 0 1 1 1 0 Adenovirus minor core protein PV AP3D1 PF06375.11 RLN95480.1 - 2.2 8.5 12.9 5.3 7.3 12.9 1.6 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Phage_C PF12025.8 RLN95481.1 - 0.031 14.1 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Phage protein C DUF3668 PF12416.8 RLN95482.1 - 2.2e-19 70.2 0.0 1.6e-18 67.3 0.0 2.3 3 0 0 3 3 3 1 Cep120 protein MIP PF00230.20 RLN95483.1 - 6.2e-06 26.1 4.5 8.5e-06 25.6 4.5 1.2 1 0 0 1 1 1 1 Major intrinsic protein ketoacyl-synt PF00109.26 RLN95483.1 - 0.013 15.1 0.1 0.014 15.0 0.1 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Glyco_hydro_31 PF01055.26 RLN95484.1 - 3.3e-153 511.0 0.4 4.6e-153 510.5 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 RLN95484.1 - 9.5e-29 100.0 0.0 1.2e-27 96.4 0.0 2.5 2 0 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase CBM_25 PF03423.13 RLN95484.1 - 3.1e-28 98.1 9.9 2.8e-14 53.3 1.2 2.6 2 0 0 2 2 2 2 Carbohydrate binding domain (family 25) CBM53 PF16760.5 RLN95484.1 - 1.9e-17 63.6 5.3 2e-08 34.7 0.6 2.6 2 0 0 2 2 2 2 Starch/carbohydrate-binding module (family 53) Gal_mutarotas_2 PF13802.6 RLN95484.1 - 1.1e-08 35.3 0.1 3.8e-08 33.5 0.1 2.0 2 0 0 2 2 2 1 Galactose mutarotase-like CBM26 PF16738.5 RLN95484.1 - 2.4e-08 34.1 5.7 0.00014 22.1 0.6 3.0 2 0 0 2 2 2 2 Starch-binding module 26 CBM_21 PF03370.13 RLN95484.1 - 0.069 13.3 2.6 3 8.1 0.3 2.6 2 0 0 2 2 2 0 Carbohydrate/starch-binding module (family 21) cNMP_binding PF00027.29 RLN95485.1 - 7.9e-12 45.1 0.0 1.5e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN95485.1 - 0.056 12.7 0.0 0.08 12.2 0.0 1.2 1 0 0 1 1 1 0 Ion transport protein Ammonium_transp PF00909.21 RLN95486.1 - 9.1e-112 373.6 34.3 1.2e-111 373.2 34.3 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family Proton_antipo_N PF00662.20 RLN95486.1 - 2.8 8.1 9.1 6.6 6.9 0.9 3.0 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Ammonium_transp PF00909.21 RLN95487.1 - 6.7e-116 387.3 33.8 8.9e-116 386.9 33.8 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family RIB43A PF05914.12 RLN95488.1 - 5e-75 252.6 52.8 5.9e-75 252.4 52.8 1.0 1 0 0 1 1 1 1 RIB43A AAA_2 PF07724.14 RLN95489.1 - 2.1e-44 151.7 0.0 4.1e-44 150.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 RLN95489.1 - 2.6e-14 53.8 0.0 5.2e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 RLN95489.1 - 1.8e-12 47.1 0.1 4e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.6 RLN95489.1 - 3.7e-05 24.0 0.2 0.00034 20.9 0.2 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 RLN95489.1 - 6.1e-05 22.8 0.3 0.0052 16.5 0.1 2.8 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RLN95489.1 - 0.00016 21.6 0.2 0.00086 19.3 0.2 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 RLN95489.1 - 0.00041 19.9 0.0 0.00094 18.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region MCM PF00493.23 RLN95489.1 - 0.00058 19.0 0.2 0.0013 17.8 0.1 1.6 2 0 0 2 2 1 1 MCM P-loop domain Sigma54_activat PF00158.26 RLN95489.1 - 0.0014 18.4 0.0 0.0071 16.1 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 RLN95489.1 - 0.0036 17.4 0.0 0.0099 16.0 0.0 1.8 1 0 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 RLN95489.1 - 0.0041 16.5 0.0 0.018 14.4 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 RLN95489.1 - 0.0042 17.1 0.0 0.0085 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RLN95489.1 - 0.0055 16.9 0.0 0.018 15.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.27 RLN95489.1 - 0.012 16.2 0.3 0.028 14.9 0.1 1.9 2 1 0 2 2 1 0 ABC transporter AAA_16 PF13191.6 RLN95489.1 - 0.014 15.8 0.5 0.064 13.6 0.1 2.4 1 1 1 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 RLN95489.1 - 0.017 14.9 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 RLN95489.1 - 0.024 14.6 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IPT PF01745.16 RLN95489.1 - 0.038 13.4 0.2 0.078 12.4 0.2 1.4 1 0 0 1 1 1 0 Isopentenyl transferase PhoH PF02562.16 RLN95489.1 - 0.045 13.2 0.1 0.12 11.8 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein TrwB_AAD_bind PF10412.9 RLN95489.1 - 0.097 11.6 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 RLN95489.1 - 0.098 11.7 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 RLN95489.1 - 0.098 13.2 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 RLN95489.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 RLN95489.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 RLN95489.1 - 0.17 12.3 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DEAD PF00270.29 RLN95489.1 - 0.19 11.5 0.5 0.71 9.6 0.2 1.9 1 1 1 2 2 2 0 DEAD/DEAH box helicase Tetraspanin PF00335.20 RLN95494.1 - 3.8e-21 75.9 36.2 2.5e-14 53.6 11.7 2.9 2 1 1 3 3 3 2 Tetraspanin family Vma12 PF11712.8 RLN95494.1 - 1.3 9.1 4.6 3.9 7.5 4.6 1.9 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF872 PF05915.12 RLN95494.1 - 3.7 7.8 12.1 8.8 6.5 3.6 2.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) CH PF00307.31 RLN95495.1 - 4.7e-09 36.4 0.1 1e-08 35.3 0.1 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain bZIP_1 PF00170.21 RLN95495.1 - 0.007 16.4 0.7 0.007 16.4 0.7 3.6 3 1 0 3 3 3 1 bZIP transcription factor FlaC_arch PF05377.11 RLN95495.1 - 0.23 11.9 5.3 8.6 6.8 0.4 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Mto2_bdg PF12808.7 RLN95495.1 - 4.9 7.5 14.4 0.6 10.4 1.3 3.5 2 1 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region HALZ PF02183.18 RLN95495.1 - 6.1 7.1 23.6 0.093 13.0 0.6 3.8 4 0 0 4 4 4 0 Homeobox associated leucine zipper Fib_alpha PF08702.10 RLN95495.1 - 8.6 6.5 8.6 31 4.7 8.6 2.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Hydrolase_4 PF12146.8 RLN95496.1 - 4.2e-06 26.2 0.1 0.0003 20.2 0.0 2.6 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 RLN95496.1 - 1.9e-05 24.7 0.0 8.2e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_6 PF12697.7 RLN95496.1 - 7.4e-05 23.4 0.0 0.0021 18.7 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN95496.1 - 0.00041 20.1 0.1 0.0012 18.5 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF5305 PF17231.2 RLN95496.1 - 0.073 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF2207 PF09972.9 RLN95496.1 - 0.19 10.4 0.4 0.47 9.2 0.1 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) KinB_sensor PF16767.5 RLN95497.1 - 0.01 16.3 4.2 0.021 15.3 3.1 2.1 2 1 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB Osteoregulin PF07175.11 RLN95497.1 - 0.11 12.7 3.5 0.22 11.7 3.5 1.4 1 0 0 1 1 1 0 Osteoregulin YihI PF04220.12 RLN95497.1 - 0.15 11.8 5.7 0.29 10.9 5.5 1.6 1 1 0 1 1 1 0 Der GTPase activator (YihI) THOC7 PF05615.13 RLN95497.1 - 0.45 10.8 8.4 1.1 9.6 8.4 2.0 1 1 0 1 1 1 0 Tho complex subunit 7 MAJIN PF15077.6 RLN95497.1 - 3.4 7.4 8.3 0.87 9.3 4.9 1.7 1 1 1 2 2 2 0 Membrane-anchored junction protein Sugar_tr PF00083.24 RLN95498.1 - 1.5e-19 70.2 17.4 1.9e-17 63.3 17.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN95498.1 - 7.7e-12 44.8 44.5 1.6e-07 30.6 12.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M16_C PF05193.21 RLN95499.1 - 8.4e-18 65.0 0.0 2.7e-17 63.4 0.0 1.8 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 RLN95499.1 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) OrfB_Zn_ribbon PF07282.11 RLN95500.1 - 9e-07 28.7 5.0 1.1e-05 25.3 5.0 2.4 1 1 0 1 1 1 1 Putative transposase DNA-binding domain Arm PF00514.23 RLN95501.1 - 3.2e-66 217.5 27.1 5.2e-06 26.3 0.0 16.4 17 0 0 17 17 17 12 Armadillo/beta-catenin-like repeat Pkinase_Tyr PF07714.17 RLN95501.1 - 5.3e-57 193.1 0.0 2.5e-42 145.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN95501.1 - 1.3e-48 165.7 0.0 6e-37 127.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain HEAT PF02985.22 RLN95501.1 - 2.5e-21 73.9 13.7 1.1 9.8 0.0 13.5 14 0 0 14 14 14 6 HEAT repeat HEAT_EZ PF13513.6 RLN95501.1 - 4.6e-17 62.1 38.0 0.00072 20.0 0.2 9.1 6 2 5 11 11 11 7 HEAT-like repeat HEAT_2 PF13646.6 RLN95501.1 - 5e-11 42.8 47.4 0.038 14.4 2.8 8.7 3 2 5 10 10 10 8 HEAT repeats DUF294_C PF10335.9 RLN95501.1 - 0.0024 17.7 3.3 4.7 7.0 0.0 6.0 3 2 4 8 8 8 1 Putative nucleotidyltransferase substrate binding domain Kinase-like PF14531.6 RLN95501.1 - 0.029 13.7 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Kinase-like MoaE PF02391.17 RLN95501.1 - 0.032 14.5 0.0 16 5.8 0.0 3.8 3 0 0 3 3 3 0 MoaE protein Ten1_2 PF15490.6 RLN95501.1 - 0.041 13.6 0.1 0.26 11.0 0.0 2.4 2 0 0 2 2 2 0 Telomere-capping, CST complex subunit PIN_2 PF10130.9 RLN95501.1 - 0.5 10.6 7.8 85 3.4 0.0 5.6 6 2 2 8 8 7 0 PIN domain Pkinase_Tyr PF07714.17 RLN95502.1 - 2.4e-57 194.2 0.0 1.6e-42 145.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN95502.1 - 2.7e-50 171.2 0.0 1.4e-38 132.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Ank_2 PF12796.7 RLN95502.1 - 2e-27 95.6 0.7 8.5e-12 45.5 0.1 4.1 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN95502.1 - 3.5e-22 78.5 0.1 3.7e-08 33.8 0.0 4.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN95502.1 - 3.6e-16 58.8 1.1 0.0033 17.8 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Arm PF00514.23 RLN95502.1 - 3.8e-16 58.5 10.4 0.00024 21.0 0.0 9.0 11 0 0 11 11 11 4 Armadillo/beta-catenin-like repeat Ank_5 PF13857.6 RLN95502.1 - 2.4e-15 56.4 0.4 0.0014 18.9 0.0 4.3 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN95502.1 - 3.3e-15 54.7 0.1 0.021 15.3 0.0 6.2 5 0 0 5 5 5 4 Ankyrin repeat HEAT_2 PF13646.6 RLN95502.1 - 2.8e-05 24.4 15.6 0.015 15.6 0.4 5.8 4 2 1 5 5 5 3 HEAT repeats HEAT_EZ PF13513.6 RLN95502.1 - 0.0026 18.2 13.6 0.4 11.2 0.2 5.0 5 0 0 5 5 4 2 HEAT-like repeat Kinase-like PF14531.6 RLN95502.1 - 0.16 11.3 0.0 1.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Kinase-like DUF4214 PF13946.6 RLN95502.1 - 0.22 11.6 1.5 0.74 9.9 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4214) NADH5_C PF06455.11 RLN95503.1 - 0.07 12.7 0.0 0.072 12.7 0.0 1.1 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus TMIE PF16038.5 RLN95503.1 - 0.86 9.5 3.3 1 9.3 3.3 1.1 1 0 0 1 1 1 0 TMIE protein WD40 PF00400.32 RLN95505.1 - 1.3e-17 63.8 8.2 7.1e-06 26.7 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat TPT PF03151.16 RLN95506.1 - 1.2e-25 90.5 15.0 1.5e-25 90.1 15.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 RLN95506.1 - 1.8e-05 24.9 26.8 0.00055 20.1 13.9 2.6 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 RLN95506.1 - 0.00063 19.0 14.1 0.001 18.4 14.1 1.3 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 RLN95506.1 - 0.2 10.9 20.6 0.28 10.4 18.7 2.1 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport TRAP_alpha PF03896.16 RLN95507.1 - 0.087 12.0 0.8 0.12 11.6 0.8 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 RLN95507.1 - 3.4 5.6 5.4 4.2 5.4 5.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi CotH PF08757.11 RLN95508.1 - 6.6e-32 111.3 0.1 1.7e-31 109.9 0.1 1.7 2 0 0 2 2 2 1 CotH kinase protein PorA PF11271.8 RLN95508.1 - 0.062 12.6 2.2 0.32 10.2 2.3 1.9 2 0 0 2 2 2 0 Porin PorA TMEM51 PF15345.6 RLN95508.1 - 0.084 12.7 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 F-box-like PF12937.7 RLN95509.1 - 0.00028 20.7 0.9 0.00028 20.7 0.9 2.9 3 0 0 3 3 3 1 F-box-like zf-C2H2 PF00096.26 RLN95509.1 - 0.0011 19.3 12.9 0.85 10.2 0.1 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type F-box PF00646.33 RLN95509.1 - 0.0061 16.4 0.9 0.022 14.7 0.9 2.0 1 0 0 1 1 1 1 F-box domain FOXP-CC PF16159.5 RLN95509.1 - 0.47 11.1 6.7 7.1 7.4 3.1 3.5 2 1 1 3 3 3 0 FOXP coiled-coil domain ATG_C PF09333.11 RLN95510.1 - 6.9e-32 109.7 0.4 6.8e-30 103.3 0.2 2.2 2 0 0 2 2 2 2 Autophagy-related protein C terminal domain VPS13_C PF16909.5 RLN95510.1 - 9.1e-05 22.3 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal CDC45 PF02724.14 RLN95510.1 - 0.036 12.4 0.0 0.046 12.0 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein PDZ_6 PF17820.1 RLN95511.1 - 1.6e-05 24.7 0.0 4.1e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RLN95511.1 - 0.0021 18.3 0.0 0.0046 17.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RLN95511.1 - 0.0026 18.1 0.0 0.0061 16.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain WD40 PF00400.32 RLN95512.1 - 1.7e-15 57.1 15.1 3.6e-08 33.9 2.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN95512.1 - 2.9e-08 33.9 2.6 0.0023 18.2 0.1 5.0 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain YfiO PF13525.6 RLN95512.1 - 0.11 12.2 0.5 0.69 9.6 0.0 2.1 2 0 0 2 2 2 0 Outer membrane lipoprotein Pkinase_Tyr PF07714.17 RLN95513.1 - 1.3e-27 96.8 0.0 1.6e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN95513.1 - 1.7e-21 76.8 0.0 2.2e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PIP49_C PF12260.8 RLN95513.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 zf-RING_2 PF13639.6 RLN95514.1 - 4.7e-08 33.2 15.9 1.7e-06 28.2 15.9 2.9 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RLN95514.1 - 6.6e-06 26.3 12.2 2.4e-05 24.5 12.2 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RLN95514.1 - 1.2e-05 25.1 7.0 7.6e-05 22.5 7.0 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 RLN95514.1 - 4.4e-05 23.4 0.0 8.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 PX domain zf-C3HC4_3 PF13920.6 RLN95514.1 - 5.5e-05 23.0 7.7 0.00013 21.8 1.9 2.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN95514.1 - 6.7e-05 22.6 6.4 6.7e-05 22.6 6.4 3.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN95514.1 - 0.00038 20.1 15.0 0.0014 18.3 2.7 3.4 2 1 1 3 3 3 2 RING-like zinc finger Prok-RING_4 PF14447.6 RLN95514.1 - 0.00048 19.9 7.2 0.0057 16.5 7.1 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 RLN95514.1 - 0.0009 19.2 6.2 0.0011 19.0 3.8 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 RLN95514.1 - 0.0035 17.4 4.5 0.0035 17.4 4.5 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger Glycolytic PF00274.19 RLN95514.1 - 0.071 11.8 0.0 0.094 11.4 0.0 1.1 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I zf-RING_5 PF14634.6 RLN95514.1 - 0.085 12.8 11.9 0.23 11.5 10.4 2.7 2 1 0 2 2 2 0 zinc-RING finger domain NDUFA12 PF05071.16 RLN95515.1 - 3.1e-15 56.8 1.0 3.1e-15 56.8 1.0 1.8 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Mito_fiss_reg PF05308.11 RLN95516.1 - 0.2 11.7 5.2 0.34 11.0 5.2 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator PDZ_6 PF17820.1 RLN95518.1 - 5.7e-10 38.9 0.0 0.038 13.8 0.0 3.4 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 RLN95518.1 - 3.3e-08 33.8 0.2 0.0024 18.2 0.1 3.4 3 0 0 3 3 3 2 PDZ domain zf-MYND PF01753.18 RLN95518.1 - 1.3e-06 28.4 8.1 2.4e-06 27.5 8.1 1.5 1 0 0 1 1 1 1 MYND finger PDZ_2 PF13180.6 RLN95518.1 - 0.018 15.4 1.0 0.35 11.2 0.2 2.5 2 0 0 2 2 2 0 PDZ domain zf-Mss51 PF13824.6 RLN95518.1 - 1.8 8.7 6.8 0.57 10.3 3.3 2.0 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 HTH_21 PF13276.6 RLN95519.1 - 1.8e-05 24.8 0.0 3.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 HTH-like domain Nucleoporin_FG PF13634.6 RLN95520.1 - 0.0063 17.3 3.1 0.15 12.9 3.1 2.4 1 1 0 1 1 1 1 Nucleoporin FG repeat region CENP-B_dimeris PF09026.10 RLN95520.1 - 2.8 8.4 9.1 7 7.1 1.3 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain ETRAMP PF09716.10 RLN95521.1 - 0.25 11.4 0.8 0.37 10.9 0.8 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) JAMP PF05571.12 RLN95521.1 - 0.65 9.6 2.4 0.92 9.1 2.4 1.2 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein Calpain_inhib PF00748.19 RLN95521.1 - 5.9 7.4 11.4 0.47 11.0 0.6 3.0 3 0 0 3 3 3 0 Calpain inhibitor RRM_5 PF13893.6 RLN95522.1 - 1.1e-21 76.7 0.0 1.7e-08 34.1 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 RLN95522.1 - 3.9e-15 55.4 0.1 1.5e-07 31.1 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 RLN95522.1 - 1.6e-14 53.9 0.1 2.5e-14 53.2 0.1 1.2 1 0 0 1 1 1 1 RRM-like domain RRM_occluded PF16842.5 RLN95522.1 - 0.026 14.4 0.1 5.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif Ank_2 PF12796.7 RLN95524.1 - 1.5e-23 83.2 0.3 2e-09 37.9 0.0 3.8 2 2 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN95524.1 - 9.6e-20 70.7 0.5 2.2e-05 24.9 0.1 5.5 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN95524.1 - 1.2e-12 46.8 0.0 0.45 11.2 0.0 7.8 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 RLN95524.1 - 1.6e-12 47.3 3.2 0.0091 16.3 0.0 7.0 4 2 4 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN95524.1 - 2.9e-06 27.5 0.9 3.4 8.3 0.0 5.5 5 2 0 5 5 5 2 Ankyrin repeat DUF1707 PF08044.11 RLN95524.1 - 0.25 11.4 5.6 14 5.9 0.1 4.6 5 1 1 6 6 6 0 Domain of unknown function (DUF1707) DUF1843 PF08898.10 RLN95524.1 - 2.5 8.7 4.0 16 6.1 0.1 4.3 5 1 0 5 5 5 0 Domain of unknown function (DUF1843) MFS_1 PF07690.16 RLN95525.1 - 2.6e-11 43.1 44.9 2.4e-07 30.0 32.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RLN95525.1 - 3e-11 42.5 14.3 3e-11 42.5 14.3 2.4 2 1 0 2 2 2 1 MFS/sugar transport protein DUF3883 PF13020.6 RLN95527.1 - 9.1e-19 67.3 0.1 2.2e-18 66.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) HATPase_c_3 PF13589.6 RLN95527.1 - 0.0037 17.1 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1887 PF09002.11 RLN95527.1 - 0.093 11.4 2.4 0.17 10.6 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1887) TetR_C_15 PF17918.1 RLN95527.1 - 0.2 12.4 1.5 5.9 7.7 0.0 4.2 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain ACT PF01842.25 RLN95528.1 - 5.3e-08 32.5 0.1 1.5e-07 31.1 0.1 1.8 1 1 0 1 1 1 1 ACT domain 2-Hacid_dh_C PF02826.19 RLN95528.1 - 0.00016 21.1 0.1 0.00099 18.5 0.1 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aminotran_5 PF00266.19 RLN95528.1 - 0.00025 20.1 0.0 0.00043 19.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V ACT_7 PF13840.6 RLN95528.1 - 0.027 14.3 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 ACT domain NHL PF01436.21 RLN95529.1 - 7.4e-20 69.9 10.8 3.7e-08 33.0 0.2 8.0 7 1 0 7 7 7 4 NHL repeat EGF_2 PF07974.13 RLN95529.1 - 3.3e-17 62.5 190.7 0.0027 18.0 10.4 14.3 12 1 1 13 13 13 12 EGF-like domain LCCL PF03815.19 RLN95529.1 - 9.3e-14 51.3 0.0 7.5e-13 48.4 0.0 2.6 2 0 0 2 2 2 1 LCCL domain SGL PF08450.12 RLN95529.1 - 8.7e-07 28.8 1.1 0.037 13.6 0.1 3.5 3 0 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region hEGF PF12661.7 RLN95529.1 - 1.2e-05 25.7 136.7 0.055 14.1 4.0 14.4 12 0 0 12 12 12 9 Human growth factor-like EGF Phage_holin_2_4 PF16082.5 RLN95529.1 - 0.028 14.1 1.2 0.099 12.4 1.2 1.9 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like EGF PF00008.27 RLN95529.1 - 0.43 10.9 151.6 0.24 11.7 1.5 13.7 12 0 0 12 12 12 0 EGF-like domain SNF2_N PF00176.23 RLN95530.1 - 3.4e-62 210.2 0.4 6.6e-62 209.2 0.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 RLN95530.1 - 9.8e-21 73.4 0.0 1.2e-09 37.9 0.0 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 RLN95530.1 - 6e-17 62.0 0.0 1.5e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN95530.1 - 3.5e-08 33.6 0.0 1.3e-07 31.7 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RLN95530.1 - 5.5e-06 26.3 0.0 1.8e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 RLN95530.1 - 8.4e-05 21.9 0.0 8.4e-05 21.9 0.0 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.29 RLN95530.1 - 0.00037 20.3 1.9 0.00037 20.3 1.9 3.5 4 0 0 4 4 4 1 PHD-finger CHDCT2 PF08074.11 RLN95530.1 - 0.071 13.3 0.0 0.071 13.3 0.0 3.5 4 0 0 4 4 4 0 CHDCT2 (NUC038) domain AAA_22 PF13401.6 RLN95530.1 - 0.095 13.0 0.8 0.43 10.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Cys_rich_CPCC PF14206.6 RLN95530.1 - 0.28 11.0 0.0 0.28 11.0 0.0 2.1 2 0 0 2 2 1 0 Cysteine-rich CPCC SelP_N PF04592.14 RLN95530.1 - 6.9 6.0 28.7 6.9 6.0 16.5 3.0 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Ank_2 PF12796.7 RLN95531.1 - 2.1e-49 166.0 38.7 9.7e-08 32.5 0.3 6.9 2 2 9 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN95531.1 - 4.2e-38 129.2 30.4 2.7e-06 27.8 0.2 10.2 4 2 8 13 13 13 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN95531.1 - 1.9e-33 114.0 34.2 0.00021 21.5 0.2 14.4 2 2 13 15 15 15 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN95531.1 - 5.6e-15 54.0 18.8 3 8.7 0.1 13.5 11 2 3 14 14 14 3 Ankyrin repeat DUF5049 PF16468.5 RLN95531.1 - 5.7e-07 29.3 0.2 9.8 6.2 0.0 8.3 5 3 6 11 11 11 1 Domain of unknown function (DUF5049) Ank PF00023.30 RLN95531.1 - 0.00036 20.9 12.7 51 4.5 0.0 10.0 6 3 2 8 8 8 0 Ankyrin repeat DUF1979 PF09322.10 RLN95531.1 - 0.0032 17.3 1.6 4.9 7.1 0.0 5.2 6 0 0 6 6 6 1 Domain of unknown function (DUF1979) PCI PF01399.27 RLN95533.1 - 5.3e-10 39.7 0.1 1.1e-09 38.7 0.1 1.5 1 0 0 1 1 1 1 PCI domain TPR_1 PF00515.28 RLN95533.1 - 0.078 12.8 0.3 1.8 8.5 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat IL1_propep PF02394.16 RLN95533.1 - 0.32 11.9 2.2 2.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Interleukin-1 propeptide 3-alpha PF03475.14 RLN95535.1 - 0.07 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 3-alpha domain F420_oxidored PF03807.17 RLN95536.1 - 0.014 15.9 0.2 0.037 14.6 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PX PF00787.24 RLN95537.1 - 0.00092 19.2 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 PX domain SprT-like PF10263.9 RLN95537.1 - 0.022 14.6 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 SprT-like family Atypical_Card PF18461.1 RLN95537.1 - 0.16 12.2 0.1 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 Atypical caspase recruitment domain zf-rbx1 PF12678.7 RLN95538.1 - 4.1e-05 23.8 7.3 4.1e-05 23.8 7.3 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 RLN95538.1 - 0.00029 21.1 9.2 0.00029 21.1 9.2 2.3 2 1 0 2 2 2 1 Ring finger domain PX PF00787.24 RLN95538.1 - 0.00076 19.4 0.1 0.0014 18.6 0.1 1.4 1 0 0 1 1 1 1 PX domain zf-ANAPC11 PF12861.7 RLN95538.1 - 0.00094 19.2 2.2 0.00094 19.2 2.2 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 RLN95538.1 - 0.0011 18.8 8.5 0.0011 18.8 8.5 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN95538.1 - 0.0076 16.2 8.6 0.0076 16.2 8.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RLN95538.1 - 0.02 14.8 5.5 0.02 14.8 5.5 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 RLN95539.1 - 0.0013 18.7 0.1 0.0021 18.0 0.1 1.4 1 0 0 1 1 1 1 PX domain Ribosomal_S18 PF01084.20 RLN95540.1 - 3.1e-18 65.7 0.6 4.5e-18 65.2 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 Astro_capsid_p PF12226.8 RLN95540.1 - 0.016 14.4 1.2 0.016 14.4 1.2 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF4611 PF15387.6 RLN95540.1 - 0.097 12.9 2.5 0.15 12.3 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) YL1 PF05764.13 RLN95540.1 - 0.99 9.5 5.5 1.3 9.1 5.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein FRQ PF09421.10 RLN95541.1 - 0.12 10.4 5.2 0.13 10.2 5.2 1.1 1 0 0 1 1 1 0 Frequency clock protein BUD22 PF09073.10 RLN95541.1 - 1.4 8.2 14.8 1.7 7.9 14.8 1.1 1 0 0 1 1 1 0 BUD22 B56 PF01603.20 RLN95542.1 - 4.1e-130 434.5 7.9 5.1e-125 417.7 1.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) AMP-binding PF00501.28 RLN95543.1 - 4.5e-196 651.5 0.1 1.1e-97 327.3 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 RLN95543.1 - 3.1e-09 37.7 0.1 0.0064 17.4 0.0 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Cyclophil_like2 PF18050.1 RLN95543.1 - 0.0018 18.2 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 2 Cyclophilin-like family DUF5115 PF17142.4 RLN95543.1 - 0.016 14.9 0.1 5.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5115) EF-hand_1 PF00036.32 RLN95545.1 - 1.2e-09 37.0 1.1 2.1e-05 23.8 0.9 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RLN95545.1 - 2.3e-09 37.5 0.4 7.3e-09 35.9 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RLN95545.1 - 1.7e-07 30.6 0.2 0.021 14.7 0.5 2.7 2 0 0 2 2 2 2 EF-hand domain ALMT PF11744.8 RLN95545.1 - 0.00014 20.9 7.9 0.013 14.4 0.0 2.6 2 0 0 2 2 2 2 Aluminium activated malate transporter EF-hand_8 PF13833.6 RLN95545.1 - 0.00026 20.8 0.1 0.0009 19.0 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair ArAE_2 PF10334.9 RLN95545.1 - 0.0083 16.0 0.0 1.5 8.6 0.0 2.7 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 SPARC_Ca_bdg PF10591.9 RLN95545.1 - 0.096 13.0 0.0 0.37 11.1 0.0 2.0 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region ArAE_2_N PF10337.9 RLN95545.1 - 0.2 10.6 4.9 0.72 8.8 4.9 1.9 1 1 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal CDC50 PF03381.15 RLN95546.1 - 1.1e-60 205.5 0.0 1.6e-60 205.0 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family HIG_1_N PF04588.13 RLN95546.1 - 0.0002 21.5 1.5 0.0002 21.5 1.5 2.8 3 0 0 3 3 3 1 Hypoxia induced protein conserved region ENOD93 PF03386.14 RLN95546.1 - 0.017 15.0 1.6 0.045 13.6 1.6 1.6 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein EF-hand_1 PF00036.32 RLN95547.1 - 7.5e-16 56.4 1.0 4.6e-07 28.9 0.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN95547.1 - 6e-12 44.5 1.0 0.00019 21.1 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 RLN95547.1 - 8.7e-12 45.3 0.9 5.9e-11 42.7 0.3 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN95547.1 - 6.2e-09 35.0 0.3 0.0039 16.6 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RLN95547.1 - 3.7e-06 26.7 2.7 0.018 14.9 0.2 3.1 3 0 0 3 3 3 2 EF-hand domain pair ArAE_2 PF10334.9 RLN95547.1 - 0.055 13.3 0.1 0.21 11.4 0.1 2.0 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 SPARC_Ca_bdg PF10591.9 RLN95547.1 - 0.065 13.6 0.0 0.21 11.9 0.0 1.9 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RLN95547.1 - 0.11 12.5 0.3 17 5.5 0.0 3.4 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand FUSC_2 PF13515.6 RLN95547.1 - 0.8 9.8 27.2 0.32 11.1 13.5 2.9 2 1 0 2 2 2 0 Fusaric acid resistance protein-like Tetraspanin PF00335.20 RLN95549.1 - 6.3e-11 42.4 16.7 6.8e-11 42.3 15.3 1.5 1 1 1 2 2 2 1 Tetraspanin family Wzy_C PF04932.15 RLN95549.1 - 0.018 14.6 1.5 0.018 14.6 1.5 1.6 2 0 0 2 2 2 0 O-Antigen ligase FA_desaturase PF00487.24 RLN95549.1 - 0.13 12.1 4.7 0.19 11.5 4.7 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Caa3_CtaG PF09678.10 RLN95549.1 - 0.71 9.3 13.0 2.9 7.3 0.6 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) DUF4293 PF14126.6 RLN95549.1 - 3.3 7.9 8.2 8.5 6.6 8.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) zf-C2HC_2 PF13913.6 RLN95550.1 - 1.3e-11 44.0 11.3 1.1e-06 28.4 3.2 2.5 2 0 0 2 2 2 2 zinc-finger of a C2HC-type FYVE PF01363.21 RLN95550.1 - 0.00019 21.5 2.8 0.0053 16.9 0.1 2.4 2 0 0 2 2 2 1 FYVE zinc finger zf-CpG_bind_C PF12269.8 RLN95550.1 - 0.026 14.3 1.3 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain zf-C2H2 PF00096.26 RLN95550.1 - 0.063 13.8 7.9 3.3 8.3 0.1 3.3 2 1 1 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN95550.1 - 0.081 13.8 11.2 0.44 11.5 0.9 3.2 2 1 1 3 3 3 0 C2H2-type zinc finger zf-CHCC PF10276.9 RLN95550.1 - 0.2 11.7 1.2 1.3 9.2 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger domain SWIB PF02201.18 RLN95551.1 - 6.4e-17 61.2 0.0 1.4e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain XPG_I PF00867.18 RLN95552.1 - 5.3e-08 33.1 0.1 5.3e-08 33.1 0.1 2.3 3 0 0 3 3 3 1 XPG I-region TFIIA PF03153.13 RLN95552.1 - 0.29 11.1 6.8 0.35 10.8 6.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TMEM138 PF14935.6 RLN95553.1 - 2.9e-10 40.8 9.9 4.1e-10 40.4 9.9 1.1 1 0 0 1 1 1 1 Transmembrane protein 138 DUF4896 PF16237.5 RLN95553.1 - 0.86 9.5 7.8 2.4 8.1 3.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4896) Peptidase_M24 PF00557.24 RLN95554.1 - 2.5e-48 164.5 0.0 3.2e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 RLN95554.1 - 8.5e-18 64.4 5.7 1.8e-17 63.4 5.7 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 RLN95554.1 - 0.0023 18.0 4.1 0.0052 16.8 4.1 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 RLN95554.1 - 0.81 9.6 5.2 1.7 8.5 5.2 1.5 1 0 0 1 1 1 0 HIT zinc finger Sugar_tr PF00083.24 RLN95555.1 - 4.5e-14 52.2 0.0 4.8e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter AAA_25 PF13481.6 RLN95559.1 - 0.0027 17.3 0.2 0.011 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.7 RLN95559.1 - 0.081 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Y_phosphatase PF00102.27 RLN95559.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ank_2 PF12796.7 RLN95560.1 - 4.5e-61 203.4 21.3 2.4e-15 56.9 1.0 13.2 11 4 3 14 14 14 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN95560.1 - 7.6e-52 173.1 28.6 1.9e-07 31.5 0.1 17.4 16 3 3 19 19 19 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN95560.1 - 8.7e-43 143.8 31.0 1.1e-06 28.8 0.0 14.6 11 3 5 16 16 16 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN95560.1 - 2e-35 116.8 29.4 0.1 13.2 0.0 19.9 24 0 0 24 24 24 9 Ankyrin repeat Ank PF00023.30 RLN95560.1 - 5.1e-33 112.1 38.3 0.00022 21.5 0.2 18.0 20 0 0 20 20 20 9 Ankyrin repeat PAN_4 PF14295.6 RLN95561.1 - 1.9e-38 130.2 42.1 2.1e-10 40.3 3.9 4.6 4 0 0 4 4 4 4 PAN domain GMC_oxred_N PF00732.19 RLN95561.1 - 4.8e-29 101.7 0.0 1.3e-28 100.3 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 RLN95561.1 - 1e-07 32.6 0.4 2.3e-07 31.5 0.4 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 RLN95561.1 - 3.8e-06 26.3 0.2 3.4e-05 23.2 0.2 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 RLN95561.1 - 7.4e-06 25.3 0.2 0.00036 19.8 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 RLN95561.1 - 2e-05 24.7 1.0 6.1e-05 23.2 0.0 2.5 3 0 0 3 3 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RLN95561.1 - 0.0089 15.6 0.8 0.085 12.4 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RLN95561.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RLN95561.1 - 0.023 13.8 0.3 0.048 12.7 0.3 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 RLN95561.1 - 0.049 12.9 0.1 0.085 12.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain PAN_2 PF08276.11 RLN95561.1 - 5.1 7.3 42.3 4.9 7.4 5.5 4.7 4 0 0 4 4 4 0 PAN-like domain LRR_8 PF13855.6 RLN95562.1 - 0.0058 16.4 0.0 0.095 12.5 0.0 2.2 2 0 0 2 2 2 1 Leucine rich repeat p450 PF00067.22 RLN95566.1 - 5.8e-11 41.8 0.0 6.6e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CoatB PF10389.9 RLN95566.1 - 0.39 10.6 2.1 0.63 9.9 0.3 2.0 2 0 0 2 2 2 0 Bacteriophage coat protein B Pkinase PF00069.25 RLN95567.1 - 1.3e-44 152.6 0.0 5.4e-43 147.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN95567.1 - 6.5e-29 101.0 0.0 2.7e-28 99.0 0.0 1.8 1 1 1 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 RLN95567.1 - 2.1e-06 27.3 0.1 3.1e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN95567.1 - 0.00026 20.4 0.2 0.00064 19.1 0.2 1.8 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 RLN95567.1 - 0.17 11.5 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family ELP6 PF09807.9 RLN95568.1 - 1.3e-21 77.2 0.2 4.4e-21 75.5 0.2 1.7 1 1 0 1 1 1 1 Elongation complex protein 6 Elong_Iki1 PF10483.9 RLN95568.1 - 0.055 13.0 0.0 0.21 11.1 0.0 1.8 1 1 0 1 1 1 0 Elongator subunit Iki1 TFIIS_C PF01096.18 RLN95569.1 - 4.1e-19 68.2 5.7 4.1e-19 68.2 5.7 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 RLN95569.1 - 6.2e-06 26.1 1.6 6.2e-06 26.1 1.6 1.8 2 0 0 2 2 2 1 Transposase zinc-ribbon domain Terminase_GpA PF05876.12 RLN95569.1 - 0.017 13.7 2.5 0.022 13.3 2.5 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zf-RRPl_C4 PF17026.5 RLN95569.1 - 0.042 14.0 3.1 0.051 13.7 3.1 1.2 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-Dof PF02701.15 RLN95569.1 - 0.042 14.0 7.9 0.17 12.0 4.9 2.2 2 0 0 2 2 2 0 Dof domain, zinc finger zinc_ribbon_4 PF13717.6 RLN95569.1 - 0.31 11.0 8.0 7.6 6.5 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Tmemb_55A PF09788.9 RLN95569.1 - 0.4 9.7 0.1 0.4 9.7 0.1 2.4 2 1 1 3 3 3 0 Transmembrane protein 55A HypA PF01155.19 RLN95569.1 - 0.64 10.1 4.3 5.9 6.9 4.4 2.1 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Tnp_zf-ribbon_2 PF13842.6 RLN95569.1 - 1.6 9.6 10.9 15 6.5 0.1 2.8 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon SpoU_methylase PF00588.19 RLN95570.1 - 2.5e-25 89.3 0.0 5.7e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 SpoU rRNA Methylase family Glyco_trans_A_1 PF09318.10 RLN95570.1 - 0.21 11.3 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 1 domain A ORC5_C PF14630.6 RLN95570.1 - 0.32 10.5 1.1 6.1 6.3 0.1 3.0 3 0 0 3 3 3 0 Origin recognition complex (ORC) subunit 5 C-terminus HSP70 PF00012.20 RLN95571.1 - 1.4e-128 429.7 0.1 1.9e-128 429.3 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN95571.1 - 2.3e-12 46.4 0.1 3.3e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 MreB/Mbl protein DEAD PF00270.29 RLN95572.1 - 7.5e-17 61.6 0.0 1.3e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 RLN95572.1 - 1.9e-16 60.5 3.0 1.9e-16 60.5 3.0 2.0 2 0 0 2 2 2 1 RecQ zinc-binding Helicase_C PF00271.31 RLN95572.1 - 1.6e-13 51.0 0.0 1e-12 48.4 0.0 2.3 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN95572.1 - 0.091 12.8 0.0 0.3 11.1 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit FAM176 PF14851.6 RLN95572.1 - 1.5 8.5 4.5 9.1 5.9 0.0 2.3 2 0 0 2 2 2 0 FAM176 family G-patch PF01585.23 RLN95574.1 - 4.2e-11 42.6 1.9 4.2e-11 42.6 1.9 2.0 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 RLN95574.1 - 3.5e-06 27.0 0.8 3.5e-06 27.0 0.8 3.3 3 1 0 3 3 3 1 G-patch domain GOLD_2 PF13897.6 RLN95574.1 - 1.8 9.0 9.4 0.58 10.7 0.2 2.3 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking DUF4604 PF15377.6 RLN95574.1 - 4.1 7.8 37.1 1.9 8.9 14.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) HA2 PF04408.23 RLN95574.1 - 6.4 7.1 15.2 11 6.4 5.4 2.6 2 0 0 2 2 2 0 Helicase associated domain (HA2) rRNA_processing PF08524.11 RLN95574.1 - 8.7 6.4 34.6 5.5 7.0 18.0 2.3 2 0 0 2 2 2 0 rRNA processing PBCV_basic_adap PF08789.10 RLN95575.1 - 0.0011 19.0 1.1 0.0031 17.6 1.1 1.8 1 0 0 1 1 1 1 PBCV-specific basic adaptor domain Baculo_LEF-11 PF06385.12 RLN95575.1 - 0.18 12.4 0.1 0.38 11.3 0.1 1.5 1 0 0 1 1 1 0 Baculovirus LEF-11 protein Rft-1 PF04506.13 RLN95576.1 - 1.7e-105 353.7 9.1 2.2e-105 353.4 9.1 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt_C PF14667.6 RLN95576.1 - 9.5e-05 22.5 7.1 9.5e-05 22.5 7.1 3.9 2 2 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain GPI2 PF06432.11 RLN95576.1 - 0.019 14.4 0.0 0.25 10.7 0.0 2.6 3 1 0 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase Nucleos_tra2_C PF07662.13 RLN95576.1 - 0.036 13.9 3.3 0.42 10.4 0.5 3.3 2 1 1 3 3 3 0 Na+ dependent nucleoside transporter C-terminus VPDSG-CTERM PF18205.1 RLN95576.1 - 0.074 12.9 1.5 0.72 9.7 0.3 3.5 2 0 0 2 2 2 0 VPDSG-CTERM motif T4SS_CagC PF16943.5 RLN95576.1 - 0.2 11.8 1.7 0.53 10.5 0.1 2.6 3 0 0 3 3 3 0 Cag pathogenicity island, type IV secretory system SET PF00856.28 RLN95577.1 - 3.1e-08 34.2 0.1 3.2e-07 30.9 0.1 2.2 1 1 0 1 1 1 1 SET domain AWS PF17907.1 RLN95577.1 - 1.2 9.2 9.2 4.3 7.4 9.2 2.0 1 1 0 1 1 1 0 AWS domain DDE_3 PF13358.6 RLN95578.1 - 5.9e-07 29.3 0.0 1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease MULE PF10551.9 RLN95579.1 - 8.4e-05 22.9 0.0 0.0003 21.2 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain Helitron_like_N PF14214.6 RLN95580.1 - 5.2e-10 39.9 0.0 5.2e-10 39.9 0.0 2.5 2 1 0 2 2 2 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 RLN95580.1 - 0.0081 15.4 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase Sugar_tr PF00083.24 RLN95581.1 - 1.1e-79 268.5 27.9 1.3e-79 268.2 27.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN95581.1 - 7.6e-19 67.8 30.0 7.6e-19 67.8 30.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_MLP1_2 PF07926.12 RLN95582.1 - 9.3e-16 58.1 30.0 9.3e-16 58.1 30.0 16.5 6 3 9 15 15 15 7 TPR/MLP1/MLP2-like protein TFA2_Winged_2 PF18121.1 RLN95582.1 - 0.014 15.1 1.8 0.18 11.5 0.1 3.6 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 BCL_N PF04714.13 RLN95582.1 - 1.6 8.9 4.2 1.8 8.7 0.3 3.3 2 0 0 2 2 2 0 BCL7, N-terminal conserver region REC1 PF18501.1 RLN95583.1 - 0.0016 18.4 3.4 0.026 14.4 2.2 2.3 2 0 0 2 2 2 1 Alpha helical recognition lobe domain FAR1 PF03101.15 RLN95583.1 - 0.011 16.4 1.8 0.033 14.9 0.0 2.4 3 0 0 3 3 3 0 FAR1 DNA-binding domain CCDC144C PF14915.6 RLN95583.1 - 0.016 14.3 3.3 0.03 13.4 3.3 1.4 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Leu_zip PF15294.6 RLN95583.1 - 0.02 14.4 0.7 0.04 13.4 0.7 1.4 1 0 0 1 1 1 0 Leucine zipper DUF3122 PF11320.8 RLN95583.1 - 0.038 14.1 0.1 0.092 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3122) ZapB PF06005.12 RLN95583.1 - 0.039 14.4 0.7 0.039 14.4 0.7 3.6 3 1 1 4 4 4 0 Cell division protein ZapB GIT_CC PF16559.5 RLN95583.1 - 0.045 13.6 0.1 0.045 13.6 0.1 2.2 3 0 0 3 3 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF724 PF05266.14 RLN95583.1 - 0.066 13.0 1.4 0.15 11.9 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Atg14 PF10186.9 RLN95583.1 - 0.066 12.3 1.2 0.15 11.1 1.2 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5340 PF17275.2 RLN95583.1 - 0.092 12.9 3.7 0.27 11.4 0.2 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5340) DUF812 PF05667.11 RLN95583.1 - 0.14 11.0 2.0 0.3 9.9 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) bZIP_2 PF07716.15 RLN95583.1 - 0.15 12.2 7.0 3.8 7.7 0.0 3.2 3 0 0 3 3 3 0 Basic region leucine zipper bZIP_1 PF00170.21 RLN95583.1 - 0.31 11.2 7.2 1.7 8.8 0.1 2.8 3 0 0 3 3 3 0 bZIP transcription factor HALZ PF02183.18 RLN95583.1 - 0.37 11.0 2.1 6.2 7.1 0.0 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper YabA PF06156.13 RLN95583.1 - 0.58 10.8 6.2 5.8 7.6 1.3 3.1 2 1 1 3 3 2 0 Initiation control protein YabA Metal_resist PF13801.6 RLN95583.1 - 0.68 10.1 6.9 2.3 8.4 1.9 3.0 2 0 0 2 2 2 0 Heavy-metal resistance Spc7 PF08317.11 RLN95583.1 - 1.2 7.9 4.8 2.5 6.9 4.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 RLN95583.1 - 1.5 8.9 5.0 0.29 11.2 1.2 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Snapin_Pallidin PF14712.6 RLN95583.1 - 1.6 9.2 5.0 2.5 8.6 0.2 2.7 2 1 0 2 2 2 0 Snapin/Pallidin Shugoshin_N PF07558.11 RLN95583.1 - 5.4 7.0 6.9 15 5.6 1.0 2.9 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Sugar_tr PF00083.24 RLN95584.1 - 2.4e-77 260.7 23.5 2.9e-77 260.5 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN95584.1 - 2.5e-18 66.2 28.6 2.5e-18 66.2 28.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily CBP_CCPA PF17040.5 RLN95585.1 - 0.17 12.5 2.4 0.26 11.9 2.4 1.3 1 0 0 1 1 1 0 Cellulose-complementing protein A Apt1 PF10351.9 RLN95585.1 - 2.9 6.7 5.9 3.2 6.5 5.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Endomucin PF07010.12 RLN95587.1 - 0.41 10.6 13.4 0.63 10.0 13.4 1.3 1 0 0 1 1 1 0 Endomucin GREB1 PF15782.5 RLN95587.1 - 1.1 6.2 6.1 1.4 6.0 6.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 RLN95587.1 - 1.3 7.9 5.5 1.8 7.5 5.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Ndc1_Nup PF09531.10 RLN95587.1 - 1.4 7.5 6.2 1.7 7.3 6.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF966 PF06136.13 RLN95587.1 - 1.5 8.5 9.2 1.8 8.2 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Mitofilin PF09731.9 RLN95587.1 - 1.6 7.5 22.0 2.1 7.1 22.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein NST1 PF13945.6 RLN95587.1 - 1.9 8.6 10.3 3.2 7.8 10.3 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator PCM1_C PF15717.5 RLN95587.1 - 2.1 6.9 13.3 2.7 6.6 13.3 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus CCSAP PF15748.5 RLN95587.1 - 4.1 7.5 18.0 5.9 7.0 18.0 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PRCC PF10253.9 RLN95587.1 - 4.4 8.0 18.8 7.1 7.4 18.8 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SWIRM-assoc_2 PF16496.5 RLN95587.1 - 7 5.4 19.0 9.6 5.0 19.0 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DUF4045 PF13254.6 RLN95587.1 - 8.8 5.9 23.4 13 5.3 23.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Herpes_DNAp_acc PF04929.12 RLN95588.1 - 0.019 13.9 0.3 0.03 13.3 0.3 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Osmo_CC PF08946.10 RLN95588.1 - 0.025 14.8 0.6 0.1 12.9 0.6 2.1 1 0 0 1 1 1 0 Osmosensory transporter coiled coil PI_PP_I PF18363.1 RLN95588.1 - 0.039 14.1 0.1 26 5.1 0.0 3.2 3 0 0 3 3 3 0 Phosphoinositide phosphatase insertion domain APP_E2 PF12925.7 RLN95588.1 - 0.04 13.6 5.2 1.1 9.0 0.1 2.9 2 1 0 2 2 2 0 E2 domain of amyloid precursor protein Goodbye PF17109.5 RLN95588.1 - 8.2 6.9 6.3 8.8 6.8 0.2 3.2 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain Cortex-I_coil PF09304.10 RLN95588.1 - 9.1 6.5 12.4 0.17 12.1 3.2 2.9 3 0 0 3 3 3 0 Cortexillin I, coiled coil AI-2E_transport PF01594.16 RLN95589.1 - 1.2e-09 37.8 18.3 1.2e-09 37.8 18.3 3.2 3 0 0 3 3 3 1 AI-2E family transporter SAYSvFN PF10260.9 RLN95589.1 - 0.98 9.4 5.6 3.1 7.8 2.2 2.9 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) RRN3 PF05327.11 RLN95589.1 - 6.1 5.3 18.0 11 4.4 18.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 EB1 PF03271.17 RLN95590.1 - 3.5e-16 59.1 0.4 7.1e-16 58.2 0.4 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif Prefoldin_2 PF01920.20 RLN95590.1 - 0.17 11.9 2.0 1.4 8.9 0.0 2.0 2 0 0 2 2 2 0 Prefoldin subunit ARL2_Bind_BART PF11527.8 RLN95591.1 - 4.8e-19 68.6 5.4 6.6e-19 68.1 5.4 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Bromo_TP PF07524.13 RLN95591.1 - 0.33 11.0 2.3 0.51 10.4 0.1 2.2 2 1 1 3 3 3 0 Bromodomain associated Toxin_11 PF07473.11 RLN95592.1 - 1.5 9.0 6.6 5 7.3 6.6 1.9 1 0 0 1 1 1 0 Spasmodic peptide gm9a; conotoxin from Conus species DUF572 PF04502.13 RLN95593.1 - 4.8 6.7 30.8 6.8 6.2 30.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Adaptin_N PF01602.20 RLN95594.1 - 4.8e-98 329.0 3.3 5.3e-89 299.2 0.4 2.0 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 RLN95594.1 - 5.5e-14 52.5 4.0 1e-10 41.9 0.0 3.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 RLN95594.1 - 0.0026 17.0 0.9 0.25 10.5 0.1 2.4 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain YL1 PF05764.13 RLN95594.1 - 0.0029 17.8 9.8 0.054 13.6 1.5 2.3 2 0 0 2 2 2 2 YL1 nuclear protein DM4_12 PF07841.13 RLN95594.1 - 0.068 13.8 0.0 0.28 11.9 0.0 2.1 1 0 0 1 1 1 0 DM4/DM12 family Cwf_Cwc_15 PF04889.12 RLN95594.1 - 0.073 12.8 10.2 0.2 11.3 2.4 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RTP1_C1 PF10363.9 RLN95594.1 - 0.078 13.2 1.7 95 3.2 0.0 4.5 4 1 1 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 B56 PF01603.20 RLN95594.1 - 0.14 11.1 0.5 0.32 9.9 0.5 1.5 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Spt5_N PF11942.8 RLN95594.1 - 0.72 10.9 14.8 0.15 13.1 5.4 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal RXT2_N PF08595.11 RLN95594.1 - 0.98 9.4 7.9 1.4 8.9 0.2 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal FAM176 PF14851.6 RLN95594.1 - 6.6 6.4 12.6 7.8 6.2 1.9 2.5 2 0 0 2 2 2 0 FAM176 family SUIM_assoc PF16619.5 RLN95595.1 - 0.78 9.9 17.4 0.98 9.5 0.0 4.8 4 1 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 LRR_4 PF12799.7 RLN95596.1 - 2.6e-05 24.5 6.8 0.0069 16.8 0.5 4.6 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RLN95596.1 - 0.0056 16.6 2.8 0.22 11.7 0.4 3.4 3 0 0 3 3 3 1 Leucine Rich repeat LRR_8 PF13855.6 RLN95596.1 - 0.2 11.4 6.4 2 8.2 0.5 4.3 4 1 1 5 5 5 0 Leucine rich repeat LRR_1 PF00560.33 RLN95596.1 - 1.5 9.7 8.6 7.2 7.6 0.1 4.6 5 0 0 5 5 5 0 Leucine Rich Repeat NOA36 PF06524.12 RLN95596.1 - 1.9 7.7 5.3 3.1 7.0 5.3 1.3 1 0 0 1 1 1 0 NOA36 protein LRR_4 PF12799.7 RLN95597.1 - 1e-06 28.9 1.8 0.0043 17.4 0.1 4.5 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN95597.1 - 0.00014 21.9 0.3 1.5 9.7 0.0 4.9 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 RLN95597.1 - 0.00059 19.7 4.9 0.88 9.8 0.1 4.8 5 0 0 5 5 5 2 Leucine Rich repeat LRR_8 PF13855.6 RLN95597.1 - 0.007 16.1 3.8 0.47 10.3 0.3 4.7 5 1 1 6 6 6 1 Leucine rich repeat LRR_12 PF18837.1 RLN95597.1 - 0.083 12.5 0.5 3.1 7.5 0.1 2.7 2 0 0 2 2 2 0 Leucine-rich repeat CWC25 PF12542.8 RLN95597.1 - 0.12 13.3 0.1 0.24 12.3 0.1 1.4 1 0 0 1 1 1 0 Pre-mRNA splicing factor Mcl1_mid PF12341.8 RLN95598.1 - 1.4e-54 185.5 0.0 2.9e-54 184.4 0.0 1.5 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 RLN95598.1 - 1.1e-05 25.7 0.0 0.32 11.3 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RLN95598.1 - 0.014 16.3 0.0 19 6.3 0.0 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat Spt5_N PF11942.8 RLN95598.1 - 1.4 9.9 10.5 3.4 8.7 10.5 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Thioredoxin PF00085.20 RLN95599.1 - 0.00017 21.5 0.0 0.00037 20.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 RLN95599.1 - 0.0002 20.4 0.1 0.00053 19.0 0.0 1.7 2 0 0 2 2 2 1 Phosducin Thioredoxin_6 PF13848.6 RLN95599.1 - 0.049 13.5 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Glu-tRNAGln PF02686.15 RLN95600.1 - 1.2e-05 25.5 0.1 1.8e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit PP2C_2 PF13672.6 RLN95601.1 - 0.083 12.5 0.0 0.098 12.3 0.0 1.0 1 0 0 1 1 1 0 Protein phosphatase 2C COMM_domain PF07258.14 RLN95602.1 - 8.1e-08 32.3 0.0 1e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 COMM domain LSM PF01423.22 RLN95603.1 - 4.6e-22 77.5 0.1 5.4e-22 77.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 RLN95603.1 - 0.02 15.0 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Glu_cyclase_2 PF05096.12 RLN95604.1 - 2.3e-71 240.2 0.5 1.2e-70 237.8 0.5 1.9 1 1 0 1 1 1 1 Glutamine cyclotransferase PAE PF03283.13 RLN95605.1 - 1.1e-12 47.7 0.6 2.1e-12 46.8 0.6 1.4 1 1 0 1 1 1 1 Pectinacetylesterase DUF2235 PF09994.9 RLN95605.1 - 0.0029 17.0 0.0 0.021 14.2 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_3 PF07859.13 RLN95605.1 - 0.12 12.2 0.0 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold adh_short PF00106.25 RLN95606.1 - 9.2e-45 152.5 5.7 3.3e-34 118.1 2.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN95606.1 - 1.4e-28 100.1 5.7 2.8e-23 82.7 0.7 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 RLN95606.1 - 3e-05 24.0 0.6 6e-05 23.0 0.2 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 RLN95606.1 - 4.6e-05 23.0 0.1 9.1e-05 22.0 0.1 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 RLN95606.1 - 8.8e-05 22.5 0.5 0.00032 20.7 0.3 2.1 2 1 0 2 2 2 1 KR domain HATPase_c_3 PF13589.6 RLN95606.1 - 0.011 15.5 0.1 0.033 14.0 0.1 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 2-Hacid_dh_C PF02826.19 RLN95606.1 - 0.038 13.3 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 RLN95606.1 - 0.069 12.2 0.8 0.11 11.5 0.1 1.8 3 0 0 3 3 3 0 RmlD substrate binding domain Spore_GerAC PF05504.11 RLN95607.1 - 0.64 10.2 4.5 1.2 9.3 4.5 1.5 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Baseplate_J PF04865.14 RLN95608.1 - 0.036 13.2 0.0 0.04 13.1 0.0 1.0 1 0 0 1 1 1 0 Baseplate J-like protein Methyltransf_24 PF13578.6 RLN95608.1 - 0.16 13.0 0.0 0.38 11.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain FMN_red PF03358.15 RLN95610.1 - 7.3e-24 84.3 0.1 1.1e-23 83.7 0.1 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 RLN95610.1 - 8.3e-06 25.6 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold BPD_transp_1 PF00528.22 RLN95610.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component DUF4940 PF16298.5 RLN95610.1 - 0.24 11.1 0.0 0.37 10.4 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4940) WD40 PF00400.32 RLN95612.1 - 0.016 16.0 0.3 7.5 7.6 0.0 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat LRR_6 PF13516.6 RLN95614.1 - 9.6e-09 34.6 18.1 0.018 15.0 0.0 6.2 6 0 0 6 6 6 5 Leucine Rich repeat LRR_1 PF00560.33 RLN95614.1 - 0.016 15.7 7.0 11 7.0 0.1 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 RLN95614.1 - 0.052 14.0 9.6 1.7 9.1 0.4 4.3 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) PRA1 PF03208.19 RLN95615.1 - 0.00055 19.6 0.1 0.0008 19.1 0.1 1.2 1 0 0 1 1 1 1 PRA1 family protein ChaC PF04752.12 RLN95616.1 - 4.4e-54 183.2 0.0 5e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 RLN95616.1 - 7.4e-06 26.6 0.2 1.7e-05 25.4 0.2 1.7 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 RLN95616.1 - 0.0003 21.1 0.0 0.00047 20.5 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family DSPc PF00782.20 RLN95616.1 - 0.065 13.0 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PX PF00787.24 RLN95617.1 - 4.2e-09 36.4 0.0 7.9e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 PX domain Ribonuc_red_sm PF00268.21 RLN95618.1 - 2.9e-116 387.8 0.6 3.4e-116 387.6 0.6 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain TPR_2 PF07719.17 RLN95619.1 - 2.6e-43 142.7 19.6 0.00015 21.6 1.1 13.7 13 0 0 13 13 12 8 Tetratricopeptide repeat TPR_1 PF00515.28 RLN95619.1 - 1.5e-34 116.4 29.7 0.00051 19.7 0.0 13.4 16 0 0 16 16 15 8 Tetratricopeptide repeat TPR_19 PF14559.6 RLN95619.1 - 1.1e-32 112.3 10.2 7.8e-07 29.5 0.0 10.3 5 4 7 12 12 12 8 Tetratricopeptide repeat TPR_16 PF13432.6 RLN95619.1 - 5.1e-31 107.1 0.6 3.2e-07 30.9 0.2 8.5 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 RLN95619.1 - 9.4e-28 94.1 15.4 0.0014 18.7 0.0 11.4 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_14 PF13428.6 RLN95619.1 - 3.4e-25 86.6 4.5 0.038 14.8 0.0 9.9 7 2 2 9 9 8 6 Tetratricopeptide repeat TPR_7 PF13176.6 RLN95619.1 - 1.3e-24 84.4 8.5 0.001 18.9 0.0 11.1 12 0 0 12 12 11 5 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN95619.1 - 2.5e-21 75.7 16.3 5.3e-06 26.6 0.0 7.1 6 1 1 7 7 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 RLN95619.1 - 1.6e-20 72.5 10.3 0.0051 16.5 0.6 11.6 9 2 3 12 12 12 5 TPR repeat TPR_6 PF13174.6 RLN95619.1 - 2.5e-19 68.6 25.9 0.047 14.3 0.0 12.2 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_12 PF13424.6 RLN95619.1 - 2.9e-19 69.1 22.9 0.00057 20.1 0.1 10.0 7 4 4 11 11 10 7 Tetratricopeptide repeat TPR_17 PF13431.6 RLN95619.1 - 1.2e-15 56.6 21.5 0.06 13.7 0.0 13.2 15 0 0 15 15 13 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN95619.1 - 3e-14 52.3 11.5 0.11 12.3 0.0 9.5 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.6 RLN95619.1 - 1.9e-07 31.1 5.9 0.63 10.2 0.0 7.1 6 2 2 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 RLN95619.1 - 1.5e-05 24.4 5.0 0.0028 16.9 0.1 5.1 4 3 1 5 5 5 1 Tetratricopeptide repeat YfiO PF13525.6 RLN95619.1 - 3.4e-05 23.7 5.9 0.13 11.9 0.3 4.4 4 0 0 4 4 4 2 Outer membrane lipoprotein TPR_4 PF07721.14 RLN95619.1 - 9.2e-05 22.7 0.0 22 6.0 0.0 6.2 6 0 0 6 6 5 0 Tetratricopeptide repeat ChAPs PF09295.10 RLN95619.1 - 0.001 18.2 0.1 0.34 9.9 0.0 3.7 4 0 0 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) NARP1 PF12569.8 RLN95619.1 - 0.0022 17.0 0.2 0.0022 17.0 0.2 5.5 3 2 3 6 6 4 1 NMDA receptor-regulated protein 1 DUF4919 PF16266.5 RLN95619.1 - 0.017 15.1 0.5 5.4 6.9 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4919) DUF4810 PF16068.5 RLN95619.1 - 0.11 13.0 12.1 4.7 7.8 0.0 6.4 5 2 1 6 6 5 0 Domain of unknown function (DUF4810) Fis1_TPR_C PF14853.6 RLN95619.1 - 0.54 10.4 23.2 2.8 8.1 1.0 6.4 5 1 1 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 RLN95619.1 - 1.4 9.1 22.4 19 5.4 0.6 6.5 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain SRP_TPR_like PF17004.5 RLN95619.1 - 6.2 6.9 15.6 2.3 8.3 0.8 5.0 4 2 1 5 5 5 0 Putative TPR-like repeat FlxA PF14282.6 RLN95620.1 - 0.64 10.0 4.8 1.1 9.2 4.1 1.8 1 1 0 1 1 1 0 FlxA-like protein IFT57 PF10498.9 RLN95620.1 - 1.1 8.2 10.8 2.1 7.2 10.8 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TPPII_N PF12583.8 RLN95620.1 - 7.8 7.1 10.3 3.6 8.2 5.4 2.7 2 1 0 2 2 2 0 Tripeptidyl peptidase II N terminal HATPase_c_5 PF14501.6 RLN95621.1 - 0.12 12.2 0.5 1.3 9.0 0.2 2.3 2 0 0 2 2 2 0 GHKL domain Exop_C PF18559.1 RLN95622.1 - 0.79 9.6 4.0 0.52 10.2 0.4 2.1 2 1 0 2 2 2 0 Galactose-binding domain-like Bac_surface_Ag PF01103.23 RLN95623.1 - 4.9e-32 111.7 0.1 3.3e-22 79.4 0.1 2.1 2 0 0 2 2 2 2 Surface antigen RRM_1 PF00076.22 RLN95624.1 - 3e-22 78.2 0.0 5.6e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN95624.1 - 0.00045 20.3 0.0 0.0016 18.5 0.0 1.9 1 1 1 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 RLN95624.1 - 0.16 11.7 0.2 0.47 10.2 0.1 1.8 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF4484 PF14831.6 RLN95625.1 - 0.054 13.5 0.3 0.074 13.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) HEAT_2 PF13646.6 RLN95626.1 - 2.6e-09 37.4 19.2 0.016 15.6 0.5 6.0 4 2 1 5 5 5 4 HEAT repeats Vac14_Fab1_bd PF12755.7 RLN95626.1 - 2.9e-08 34.2 0.4 0.11 13.1 0.0 5.0 4 2 1 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 RLN95626.1 - 2e-07 31.2 5.6 0.018 15.1 0.0 5.5 4 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RLN95626.1 - 5.3e-07 29.4 28.8 1.5 9.3 0.1 10.3 10 1 1 11 11 11 3 HEAT repeat Sec7_N PF12783.7 RLN95626.1 - 0.0036 17.2 1.2 0.059 13.3 0.0 3.1 2 2 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_EZ PF13513.6 RLN95626.1 - 0.02 15.4 21.4 1.9 9.1 0.1 7.9 7 1 2 9 9 9 0 HEAT-like repeat Dopey_N PF04118.14 RLN95626.1 - 0.055 12.6 0.1 11 5.0 0.0 3.0 3 0 0 3 3 3 0 Dopey, N-terminal ClpB_D2-small PF10431.9 RLN95626.1 - 0.095 12.8 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein Not3 PF04065.15 RLN95629.1 - 5.8e-85 284.4 23.0 7.5e-85 284.0 23.0 1.1 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 RLN95629.1 - 6.4e-43 146.0 8.3 1.6e-42 144.6 8.3 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF1664 PF07889.12 RLN95629.1 - 0.28 11.2 8.7 0.17 11.9 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) REC1 PF18501.1 RLN95629.1 - 4.1 7.2 16.5 1.2 9.0 1.7 2.2 2 0 0 2 2 2 0 Alpha helical recognition lobe domain DUF2203 PF09969.9 RLN95629.1 - 7.2 7.4 9.1 0.77 10.5 1.1 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Med29 PF11568.8 RLN95630.1 - 0.006 16.8 0.1 0.0078 16.4 0.1 1.2 1 0 0 1 1 1 1 Mediator complex subunit 29 DUF4570 PF15134.6 RLN95630.1 - 0.045 13.8 0.3 0.078 13.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) Vac14_Fab1_bd PF12755.7 RLN95633.1 - 0.00062 20.3 0.0 0.00088 19.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 RLN95633.1 - 0.013 15.7 0.4 0.59 10.5 0.1 2.9 2 0 0 2 2 2 0 HEAT repeat MMS19_N PF14500.6 RLN95633.1 - 0.021 14.4 0.0 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II Dopey_N PF04118.14 RLN95633.1 - 0.031 13.4 0.1 0.042 13.0 0.1 1.3 1 1 0 1 1 1 0 Dopey, N-terminal IFRD PF05004.13 RLN95633.1 - 0.051 12.7 0.1 0.076 12.1 0.1 1.3 1 1 0 1 1 1 0 Interferon-related developmental regulator (IFRD) DUF4620 PF15399.6 RLN95633.1 - 0.07 13.5 2.6 0.32 11.4 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4620) Ipi1_N PF12333.8 RLN95633.1 - 0.099 13.2 0.5 0.27 11.8 0.1 1.9 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation ParcG PF10274.9 RLN95633.1 - 0.15 12.2 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Parkin co-regulated protein Cytomega_US3 PF05963.11 RLN95633.1 - 0.16 11.7 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus US3 protein Cript PF10235.9 RLN95634.1 - 8.5e-17 61.5 2.4 1.8e-16 60.5 2.4 1.6 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT PHF5 PF03660.14 RLN95634.1 - 0.014 15.6 0.5 0.014 15.6 0.5 1.8 2 0 0 2 2 2 0 PHF5-like protein DZR PF12773.7 RLN95634.1 - 0.029 14.4 4.4 0.077 13.0 4.4 1.7 1 1 0 1 1 1 0 Double zinc ribbon C1_2 PF03107.16 RLN95634.1 - 0.029 14.7 1.9 0.029 14.7 1.9 1.9 2 0 0 2 2 2 0 C1 domain zinc_ribbon_15 PF17032.5 RLN95634.1 - 0.13 13.1 6.6 0.49 11.2 6.6 2.0 1 1 0 1 1 1 0 zinc-ribbon family Rdx PF10262.9 RLN95634.1 - 0.36 11.1 1.3 0.85 9.9 1.3 1.7 1 1 0 1 1 1 0 Rdx family ELMO_CED12 PF04727.13 RLN95636.1 - 2.7e-19 70.0 0.0 1.7e-18 67.3 0.0 1.9 1 1 0 1 1 1 1 ELMO/CED-12 family CSRNP_N PF16019.5 RLN95639.1 - 0.054 13.4 0.1 0.068 13.1 0.1 1.5 1 1 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus CSRNP_N PF16019.5 RLN95640.1 - 0.00024 21.1 1.9 0.0035 17.3 0.0 2.0 1 1 1 2 2 2 2 Cysteine/serine-rich nuclear protein N-terminus HSP70 PF00012.20 RLN95643.1 - 3e-124 415.4 0.6 3.4e-124 415.3 0.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN95643.1 - 2.1e-08 33.4 0.5 3.1e-08 32.8 0.5 1.2 1 0 0 1 1 1 1 MreB/Mbl protein PX PF00787.24 RLN95644.1 - 6e-26 90.7 0.0 7.2e-26 90.4 0.0 1.0 1 0 0 1 1 1 1 PX domain Sugar_tr PF00083.24 RLN95645.1 - 5.2e-15 55.2 0.5 5.7e-15 55.1 0.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN95645.1 - 0.00051 19.1 0.2 0.00056 18.9 0.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily GWT1 PF06423.12 RLN95645.1 - 0.0029 17.8 0.0 0.0032 17.6 0.0 1.1 1 0 0 1 1 1 1 GWT1 Glyco_hydro_30 PF02055.16 RLN95646.1 - 2.5e-88 296.4 0.6 3.2e-88 296.0 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Ricin_B_lectin PF00652.22 RLN95646.1 - 6.3e-11 42.6 4.3 6.9e-10 39.3 1.6 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Glyco_hydro_30C PF17189.4 RLN95646.1 - 9.1e-08 32.2 0.1 2e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 RLN95646.1 - 1.9e-07 30.6 0.0 3.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 RLN95646.1 - 5.1e-05 23.0 0.0 0.00019 21.2 0.0 1.8 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 RicinB_lectin_2 PF14200.6 RLN95646.1 - 0.00015 22.4 0.4 0.0084 16.8 0.2 2.6 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like TolA_bind_tri PF16331.5 RLN95647.1 - 0.0058 16.7 13.2 0.0058 16.7 13.2 4.2 3 1 0 3 3 3 2 TolA binding protein trimerisation TetR_C_13 PF16925.5 RLN95647.1 - 0.76 9.7 0.0 0.76 9.7 0.0 3.0 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF1444 PF07285.11 RLN95647.1 - 1.1 8.7 6.3 0.38 10.3 3.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1444) ApoO PF09769.9 RLN95647.1 - 5.3 7.0 6.7 3 7.8 1.3 2.7 1 1 1 2 2 2 0 Apolipoprotein O Methyltransf_16 PF10294.9 RLN95648.1 - 5.9e-11 42.4 0.0 1.8e-10 40.8 0.0 1.6 1 1 1 2 2 2 1 Lysine methyltransferase Herpes_UL46 PF03387.14 RLN95648.1 - 0.21 10.3 0.0 0.57 8.8 0.0 1.6 2 0 0 2 2 2 0 Herpesvirus UL46 protein IQ PF00612.27 RLN95649.1 - 1.4e-11 43.1 36.9 0.006 16.3 0.6 7.5 7 0 0 7 7 7 5 IQ calmodulin-binding motif WW PF00397.26 RLN95649.1 - 1e-05 25.5 0.2 1e-05 25.5 0.2 3.6 4 0 0 4 4 4 1 WW domain CEBP_ZZ PF16366.5 RLN95649.1 - 0.79 10.0 44.5 0.22 11.8 0.9 6.1 6 0 0 6 6 6 0 Cytoplasmic polyadenylation element-binding protein ZZ domain ThiF PF00899.21 RLN95649.1 - 1.5 8.1 5.1 0.16 11.3 0.2 1.7 2 0 0 2 2 2 0 ThiF family zf-B_box PF00643.24 RLN95649.1 - 9.8 6.4 47.6 0.014 15.5 6.3 5.4 5 0 0 5 5 5 0 B-box zinc finger SNase PF00565.17 RLN95650.1 - 5.9e-19 68.5 0.0 8e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Pkinase PF00069.25 RLN95651.1 - 2.5e-75 253.2 0.0 3.5e-75 252.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN95651.1 - 1.1e-35 123.1 0.0 1.5e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 RLN95651.1 - 4.3e-07 30.4 0.0 9.3e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 PH domain EF-hand_1 PF00036.32 RLN95651.1 - 8.2e-05 21.9 0.4 0.00053 19.4 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RLN95651.1 - 0.00069 19.3 3.0 0.0064 16.3 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 RLN95651.1 - 0.0013 19.2 1.0 0.0084 16.5 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair Kinase-like PF14531.6 RLN95651.1 - 0.0026 17.1 0.1 0.11 11.8 0.0 2.4 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 RLN95651.1 - 0.039 13.3 0.0 0.088 12.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_5 PF13202.6 RLN95651.1 - 0.066 12.7 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 RLN95651.1 - 0.074 12.9 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair APH PF01636.23 RLN95651.1 - 0.084 12.8 0.0 0.16 11.8 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 RLN95651.1 - 0.087 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 PBS_linker_poly PF00427.21 RLN95651.1 - 0.17 12.0 0.2 0.45 10.5 0.1 1.7 2 0 0 2 2 2 0 Phycobilisome Linker polypeptide IQ PF00612.27 RLN95652.1 - 0.066 13.0 3.2 0.067 13.0 0.7 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif GCS PF03074.16 RLN95653.1 - 4.4e-156 519.8 0.0 5.7e-156 519.5 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase RXT2_N PF08595.11 RLN95654.1 - 0.0076 16.3 0.2 0.012 15.7 0.2 1.2 1 0 0 1 1 1 1 RXT2-like, N-terminal PBP1_TM PF14812.6 RLN95654.1 - 0.23 11.8 6.5 0.43 11.0 6.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4140 PF13600.6 RLN95654.1 - 0.44 11.0 5.2 0.19 12.2 0.8 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Herpes_DNAp_acc PF04929.12 RLN95654.1 - 5.5 5.8 7.5 5.6 5.8 7.5 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor PGA2 PF07543.12 RLN95654.1 - 8.5 6.4 10.2 1.4 8.9 5.9 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 Cactin_mid PF10312.9 RLN95655.1 - 3.5e-58 196.6 6.1 3.5e-58 196.6 6.1 1.5 2 0 0 2 2 2 1 Conserved mid region of cactin POTRA_TamA_1 PF17243.2 RLN95655.1 - 3.6 7.7 12.4 1.1 9.4 0.1 4.4 3 1 1 4 4 4 0 POTRA domain TamA domain 1 Sulfatase PF00884.23 RLN95656.1 - 2.8e-29 102.5 0.2 5.9e-29 101.4 0.2 1.6 1 1 0 1 1 1 1 Sulfatase DUF229 PF02995.17 RLN95656.1 - 5.5e-06 25.3 0.0 1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 RLN95656.1 - 0.00081 19.1 0.0 0.0021 17.7 0.0 1.8 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Voltage_CLC PF00654.20 RLN95656.1 - 0.032 13.5 0.2 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Voltage gated chloride channel Kazal_2 PF07648.15 RLN95657.1 - 2.2e-31 107.7 30.2 6e-13 48.7 7.0 3.1 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 RLN95657.1 - 1.7e-29 101.5 21.2 6.6e-11 42.0 4.0 3.2 1 1 2 3 3 3 3 Kazal-type serine protease inhibitor domain DUF1748 PF08520.10 RLN95657.1 - 0.12 12.3 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) BAF PF02961.14 RLN95658.1 - 0.066 13.7 0.2 0.29 11.6 0.0 2.0 2 1 1 3 3 3 0 Barrier to autointegration factor IMS_HHH PF11798.8 RLN95658.1 - 0.16 12.4 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 IMS family HHH motif CxC6 PF18721.1 RLN95659.1 - 2.6 8.4 12.5 0.27 11.5 2.7 2.7 1 1 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases Homoserine_dh PF00742.19 RLN95660.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase Vac_ImportDeg PF09783.9 RLN95660.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Vacuolar import and degradation protein Lactamase_B PF00753.27 RLN95661.1 - 2.6e-15 57.0 0.1 4.4e-15 56.2 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 RLN95661.1 - 1.7e-06 27.9 0.0 4.2e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 RLN95661.1 - 2.2e-06 27.3 0.0 3.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PET10 PF17316.2 RLN95662.1 - 0.17 11.4 0.1 0.24 10.9 0.1 1.1 1 0 0 1 1 1 0 Petite colonies protein 10 CTP_transf_like PF01467.26 RLN95663.1 - 3.5e-08 33.8 0.0 7.3e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 RLN95663.1 - 0.017 15.0 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 FAD synthetase BLACT_WH PF17778.1 RLN95664.1 - 8.3e-08 32.1 0.2 2.2e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain FYVE_2 PF02318.16 RLN95665.1 - 0.032 14.5 6.3 0.095 12.9 6.3 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger CEBP_ZZ PF16366.5 RLN95665.1 - 0.061 13.6 7.7 4.2 7.7 7.7 2.7 1 1 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Prok-RING_2 PF14445.6 RLN95665.1 - 0.12 12.5 3.2 0.33 11.2 3.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 DUF2162 PF09930.9 RLN95665.1 - 0.13 11.7 0.5 0.18 11.2 0.5 1.1 1 0 0 1 1 1 0 Predicted transporter (DUF2162) FYVE PF01363.21 RLN95665.1 - 0.5 10.6 11.2 1.3 9.2 11.2 1.7 1 0 0 1 1 1 0 FYVE zinc finger FMN_red PF03358.15 RLN95669.1 - 3.2e-10 39.9 0.0 4.9e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 RLN95669.1 - 0.0074 16.0 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold Aminotran_5 PF00266.19 RLN95670.1 - 1.5e-36 126.2 0.0 1.9e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Metallophos PF00149.28 RLN95671.1 - 1.9e-10 41.6 1.0 9.8e-10 39.3 1.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5107 PF17128.4 RLN95671.1 - 0.0062 15.8 3.0 0.011 14.9 3.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5107) Wzz PF02706.15 RLN95671.1 - 0.008 16.5 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 Chain length determinant protein DUF2749 PF10907.8 RLN95671.1 - 0.19 11.9 2.0 0.73 10.0 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) ScdA_N PF04405.14 RLN95671.1 - 0.37 10.5 3.4 1 9.1 3.4 1.7 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) ABC_tran PF00005.27 RLN95673.1 - 2.3e-46 157.7 0.4 1.4e-27 96.9 0.0 3.5 2 1 1 3 3 3 3 ABC transporter ABC2_membrane_3 PF12698.7 RLN95673.1 - 9e-42 143.4 26.7 2.4e-31 109.1 7.6 2.6 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 RLN95673.1 - 4.5e-24 85.8 0.3 1.1e-08 35.3 0.0 4.2 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RLN95673.1 - 2.6e-05 24.8 0.8 0.03 14.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain MukB PF04310.12 RLN95673.1 - 5.9e-05 23.0 1.0 0.082 12.7 0.1 2.3 2 0 0 2 2 2 2 MukB N-terminal RsgA_GTPase PF03193.16 RLN95673.1 - 0.00067 19.6 0.1 0.67 9.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 RLN95673.1 - 0.0013 18.5 1.2 0.14 11.9 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF4162 PF13732.6 RLN95673.1 - 0.0048 17.6 0.1 2 9.2 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4162) AAA_22 PF13401.6 RLN95673.1 - 0.0069 16.7 0.1 2.3 8.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RLN95673.1 - 0.0089 15.8 0.5 2.4 7.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 RLN95673.1 - 0.0095 15.4 0.0 8.1 5.8 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 RLN95673.1 - 0.017 14.8 0.0 0.55 9.9 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain SRP54 PF00448.22 RLN95673.1 - 0.07 12.8 3.3 2.3 7.8 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA PF00004.29 RLN95673.1 - 0.16 12.4 0.3 26 5.3 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MAGP PF05507.11 RLN95674.1 - 4.7 7.6 7.5 9.6 6.6 6.9 1.9 1 1 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) Glyco_hydro_12 PF01670.16 RLN95676.1 - 0.01 15.8 4.2 0.011 15.7 0.4 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 12 Elicitin PF00964.17 RLN95677.1 - 0.00032 20.7 13.4 0.018 15.1 4.1 3.2 2 2 0 2 2 2 2 Elicitin CH PF00307.31 RLN95678.1 - 5.7e-75 248.5 3.0 2.3e-19 69.6 0.1 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain Swi3 PF07962.12 RLN95678.1 - 7.2e-16 57.9 0.0 1.8e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 CAMSAP_CH PF11971.8 RLN95678.1 - 8e-09 35.2 0.4 0.075 12.9 0.0 4.5 4 0 0 4 4 4 2 CAMSAP CH domain DUF5580 PF17743.1 RLN95678.1 - 0.032 12.8 0.0 0.05 12.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5580) CH_2 PF06294.11 RLN95678.1 - 0.13 12.4 0.5 38 4.5 0.0 4.0 4 0 0 4 4 4 0 CH-like domain in sperm protein EF-hand_7 PF13499.6 RLN95678.1 - 0.16 12.5 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair DUF4834 PF16118.5 RLN95679.1 - 0.02 15.8 0.1 0.038 14.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SusD_RagB PF07980.11 RLN95679.1 - 0.31 10.6 5.4 0.64 9.6 5.4 1.6 1 0 0 1 1 1 0 SusD family SecG PF03840.14 RLN95679.1 - 0.5 10.5 3.4 1.2 9.3 3.4 1.6 1 0 0 1 1 1 0 Preprotein translocase SecG subunit Metallophos PF00149.28 RLN95680.1 - 8.8e-07 29.6 0.8 5e-06 27.2 0.8 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Alpha_GJ PF03229.13 RLN95680.1 - 0.08 13.5 9.4 0.2 12.2 9.4 1.6 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF4834 PF16118.5 RLN95680.1 - 0.18 12.8 0.1 0.37 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SecG PF03840.14 RLN95680.1 - 0.37 10.9 3.6 0.91 9.6 3.6 1.7 1 0 0 1 1 1 0 Preprotein translocase SecG subunit TFIIF_alpha PF05793.12 RLN95680.1 - 1 7.9 3.1 1.5 7.3 3.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4055 PF13264.6 RLN95687.1 - 0.26 11.5 0.7 0.54 10.4 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) NMT1 PF09084.11 RLN95689.1 - 0.049 13.6 0.2 0.075 13.0 0.2 1.2 1 0 0 1 1 1 0 NMT1/THI5 like SAM_1 PF00536.30 RLN95690.1 - 1.3e-12 47.9 0.1 4.1e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RLN95690.1 - 9.8e-12 44.8 0.0 2.7e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FliJ PF02050.16 RLN95690.1 - 0.082 13.1 20.4 0.12 12.6 2.6 3.4 3 0 0 3 3 3 0 Flagellar FliJ protein Rx_N PF18052.1 RLN95690.1 - 0.15 12.4 3.8 0.96 9.8 0.9 2.7 2 0 0 2 2 2 0 Rx N-terminal domain DUF4140 PF13600.6 RLN95690.1 - 0.61 10.6 4.7 0.61 10.6 1.0 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Cep57_MT_bd PF06657.13 RLN95690.1 - 1 9.9 6.7 0.14 12.6 1.9 2.1 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF3944 PF13099.6 RLN95690.1 - 1.4 8.8 5.2 6 6.8 1.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3944) DRIM PF07539.12 RLN95691.1 - 5.5e-125 418.1 6.1 5.5e-125 418.1 6.1 5.1 5 0 0 5 5 5 1 Down-regulated in metastasis HEAT PF02985.22 RLN95691.1 - 1.1e-07 31.4 30.2 0.61 10.5 0.2 11.3 12 0 0 12 12 12 4 HEAT repeat BLM10_mid PF16507.5 RLN95691.1 - 0.00022 20.0 0.1 0.00067 18.4 0.1 1.8 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region Mlh1_C PF16413.5 RLN95691.1 - 0.036 13.4 2.5 11 5.3 0.0 3.6 3 0 0 3 3 3 0 DNA mismatch repair protein Mlh1 C-terminus Folliculin PF11704.8 RLN95691.1 - 0.1 12.5 0.3 3.1 7.6 0.0 3.3 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport HEAT_EZ PF13513.6 RLN95691.1 - 1.1 9.8 23.0 8.9 6.9 0.4 9.4 7 1 1 8 8 8 0 HEAT-like repeat RRN3 PF05327.11 RLN95691.1 - 1.4 7.3 7.4 0.17 10.4 1.9 2.3 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.13 RLN95691.1 - 1.9 8.3 13.4 1.8 8.4 5.5 3.7 3 0 0 3 3 3 0 Sigma-70, non-essential region Band_7 PF01145.25 RLN95692.1 - 2.3e-28 99.4 0.0 2.3e-28 99.4 0.0 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 RLN95692.1 - 2.5e-28 97.9 0.3 6e-28 96.7 0.3 1.7 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7_1 PF13421.6 RLN95692.1 - 0.067 12.9 0.0 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 SPFH domain-Band 7 family Sugar_tr PF00083.24 RLN95693.1 - 1.4e-26 93.4 2.8 1.6e-26 93.2 2.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN95693.1 - 5.5e-09 35.4 8.7 5.5e-09 35.4 8.7 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.16 RLN95693.1 - 0.0086 14.3 0.2 0.011 14.0 0.2 1.1 1 0 0 1 1 1 1 BT1 family TRI12 PF06609.13 RLN95693.1 - 0.045 12.2 0.2 0.055 11.9 0.2 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) 7TM-7TMR_HD PF07698.11 RLN95693.1 - 0.12 12.1 2.3 0.12 12.1 0.4 1.7 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase bZIP_2 PF07716.15 RLN95694.1 - 0.006 16.6 2.9 0.016 15.3 2.9 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 RLN95694.1 - 0.2 11.8 1.0 0.39 10.8 1.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor Sugar_tr PF00083.24 RLN95696.1 - 1.1e-100 337.6 24.4 1.3e-100 337.4 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN95696.1 - 1.5e-24 86.6 30.0 4.3e-17 62.1 11.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Band_7 PF01145.25 RLN95697.1 - 5.6e-13 49.3 0.1 7.1e-13 48.9 0.1 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Myosin_head PF00063.21 RLN95698.1 - 5.2e-188 626.4 0.0 1.5e-146 489.4 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) FYVE PF01363.21 RLN95698.1 - 1e-16 60.8 6.7 2.2e-16 59.7 6.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger IQ PF00612.27 RLN95698.1 - 7e-09 34.7 25.0 0.085 12.7 0.7 6.1 5 0 0 5 5 5 5 IQ calmodulin-binding motif AAA_16 PF13191.6 RLN95698.1 - 0.002 18.6 3.6 0.22 11.9 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 RLN95698.1 - 0.016 14.2 0.0 0.042 12.9 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 RLN95698.1 - 0.018 15.3 0.0 0.059 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain zf-CRD PF17979.1 RLN95698.1 - 1.3 9.1 4.9 3.2 7.8 4.9 1.6 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions C5HCH PF17982.1 RLN95698.1 - 3 8.1 7.5 4.6 7.5 6.4 1.8 2 0 0 2 2 2 0 NSD Cys-His rich domain zf-AN1 PF01428.16 RLN95698.1 - 6.4 7.0 9.3 15 5.9 9.3 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger PHD PF00628.29 RLN95699.1 - 1.8e-09 37.3 8.7 4.5e-09 36.1 8.7 1.7 1 0 0 1 1 1 1 PHD-finger IQ PF00612.27 RLN95699.1 - 0.00014 21.3 17.0 0.34 10.8 0.4 5.4 4 0 0 4 4 4 3 IQ calmodulin-binding motif LRR_9 PF14580.6 RLN95699.1 - 0.001 18.6 0.0 0.0026 17.3 0.0 1.6 1 0 0 1 1 1 1 Leucine-rich repeat PHD_3 PF13922.6 RLN95699.1 - 0.11 12.9 1.7 0.48 10.8 1.7 2.1 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx LRR_4 PF12799.7 RLN95699.1 - 0.14 12.7 0.9 1.5 9.4 0.1 2.9 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) PHD_2 PF13831.6 RLN95699.1 - 0.15 11.6 3.2 0.3 10.7 3.2 1.5 1 0 0 1 1 1 0 PHD-finger MukB PF04310.12 RLN95699.1 - 2.8 7.7 5.1 6.3 6.5 0.5 2.4 2 0 0 2 2 2 0 MukB N-terminal FlaC_arch PF05377.11 RLN95699.1 - 8.2 6.9 5.9 38 4.8 0.0 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) USP7_ICP0_bdg PF12436.8 RLN95700.1 - 2.2e-55 187.6 0.0 3.1e-49 167.4 0.0 3.8 1 1 1 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.29 RLN95700.1 - 2.9e-48 164.6 0.1 5.1e-48 163.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 RLN95700.1 - 4.9e-29 101.5 0.0 1.3e-28 100.1 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.6 RLN95700.1 - 5.8e-21 75.4 0.0 1.2e-20 74.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 RLN95700.1 - 0.0014 18.4 0.0 0.75 9.6 0.0 3.0 3 0 0 3 3 3 2 Ubiquitin family Peptidase_C98 PF15499.6 RLN95700.1 - 0.0051 16.3 0.3 0.035 13.6 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase UN_NPL4 PF11543.8 RLN95700.1 - 0.0052 17.2 0.0 11 6.5 0.0 3.6 3 0 0 3 3 3 1 Nuclear pore localisation protein NPL4 Ubiquitin_2 PF14560.6 RLN95700.1 - 0.14 12.7 0.0 25 5.4 0.0 3.2 3 0 0 3 3 3 0 Ubiquitin-like domain AMP-binding PF00501.28 RLN95703.1 - 1e-34 119.9 0.0 1.7e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AAA_18 PF13238.6 RLN95704.1 - 0.045 14.3 0.4 0.15 12.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain Peptidase_S9 PF00326.21 RLN95706.1 - 1.4e-05 24.7 0.0 9.4e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 RLN95706.1 - 0.0006 20.5 0.6 0.0011 19.6 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN95706.1 - 0.0013 18.0 0.0 0.021 14.1 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 RLN95706.1 - 0.0021 17.6 0.1 0.55 9.7 0.0 2.5 2 0 0 2 2 2 2 Esterase PHB depolymerase DUF3209 PF11483.8 RLN95706.1 - 0.086 13.3 0.1 0.16 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) Retrotrans_gag PF03732.17 RLN95708.1 - 2.9e-08 33.9 0.1 4.8e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein PhoLip_ATPase_C PF16212.5 RLN95710.1 - 1.4e-66 224.8 22.1 1.4e-66 224.8 22.1 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RLN95710.1 - 2.2e-25 88.1 1.8 7.2e-25 86.5 1.8 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RLN95710.1 - 2.2e-10 41.2 0.1 0.0004 20.7 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN95710.1 - 2.5e-10 40.3 0.0 1.5e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RLN95710.1 - 9.8e-05 21.9 0.0 0.0003 20.3 0.0 1.8 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RLN95710.1 - 0.0012 18.7 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FYVE PF01363.21 RLN95715.1 - 1.8e-16 60.0 12.4 3.7e-16 59.0 12.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 RLN95715.1 - 3.1e-10 40.8 0.9 8.5e-10 39.4 0.3 2.0 2 0 0 2 2 2 1 GAF domain FYVE_2 PF02318.16 RLN95715.1 - 0.0017 18.5 7.5 0.0049 17.1 7.5 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger GAF_3 PF13492.6 RLN95715.1 - 0.014 15.8 0.0 0.055 13.8 0.0 2.1 1 1 0 1 1 1 0 GAF domain HTH_Tnp_Tc5 PF03221.16 RLN95716.1 - 1.6e-09 37.6 0.0 3e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_Tnp_1 PF01527.20 RLN95716.1 - 0.35 11.2 3.0 1.8 8.9 0.4 2.4 1 1 1 2 2 2 0 Transposase LRR_8 PF13855.6 RLN95717.1 - 9.1e-40 134.2 104.5 1.7e-10 40.5 4.6 9.0 5 3 6 12 12 12 10 Leucine rich repeat LRR_4 PF12799.7 RLN95717.1 - 2.1e-37 126.5 50.9 5.6e-06 26.6 0.4 10.0 7 1 4 11 11 11 10 Leucine Rich repeats (2 copies) WW PF00397.26 RLN95717.1 - 1.8e-17 63.1 0.8 1.7e-07 31.2 0.0 3.4 3 0 0 3 3 3 3 WW domain LRR_1 PF00560.33 RLN95717.1 - 3.4e-05 23.8 39.9 38 5.4 0.0 13.9 15 1 0 15 15 13 0 Leucine Rich Repeat Glyco_hyd_101C PF17451.2 RLN95717.1 - 0.00061 20.1 2.2 1.4 9.3 0.1 3.4 3 1 1 4 4 4 2 Glycosyl hydrolase 101 beta sandwich domain LRR_6 PF13516.6 RLN95717.1 - 0.0019 18.1 49.6 5.5 7.3 0.2 12.6 13 0 0 13 13 13 3 Leucine Rich repeat TPR_1 PF00515.28 RLN95717.1 - 0.0041 16.9 3.3 2.2 8.2 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat IQ PF00612.27 RLN95717.1 - 0.078 12.8 1.8 0.23 11.3 1.8 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif TPR_2 PF07719.17 RLN95717.1 - 0.11 12.6 15.7 0.15 12.3 0.2 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 RLN95717.1 - 0.12 12.7 0.1 3.9 7.9 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN95717.1 - 0.49 11.1 5.5 14 6.6 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_23 PF13489.6 RLN95719.1 - 0.00018 21.4 0.0 0.0004 20.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain DUF3827 PF12877.7 RLN95719.1 - 0.00095 17.7 4.0 0.01 14.3 0.3 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3827) zf-MYND PF01753.18 RLN95719.1 - 0.0031 17.6 11.5 0.0031 17.6 11.5 2.0 2 0 0 2 2 2 1 MYND finger Methyltransf_25 PF13649.6 RLN95719.1 - 0.036 14.8 0.0 0.12 13.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 RLN95719.1 - 0.14 12.2 0.0 0.14 12.2 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain CytochromB561_N PF09786.9 RLN95719.1 - 2.4 7.0 5.5 0.15 11.0 0.2 1.6 2 0 0 2 2 2 0 Cytochrome B561, N terminal UCH PF00443.29 RLN95720.1 - 2.2e-75 253.5 0.0 3e-75 253.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN95720.1 - 1.4e-11 44.6 0.0 2.6e-05 24.0 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 RLN95720.1 - 0.00017 22.1 0.3 0.0012 19.4 0.3 2.4 1 1 0 1 1 1 1 DUSP domain MBT PF02820.18 RLN95720.1 - 0.00039 20.7 0.2 0.049 14.0 0.2 2.5 2 0 0 2 2 2 1 mbt repeat Tudor-knot PF11717.8 RLN95720.1 - 0.0085 16.0 4.0 0.16 11.9 2.5 2.7 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain CUE PF02845.16 RLN95720.1 - 0.014 15.1 0.1 0.028 14.1 0.1 1.4 1 0 0 1 1 1 0 CUE domain Tudor_4 PF18358.1 RLN95720.1 - 0.019 14.5 1.1 0.061 12.9 1.1 2.0 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain SAWADEE PF16719.5 RLN95720.1 - 0.087 12.8 0.6 0.18 11.8 0.6 1.5 1 0 0 1 1 1 0 SAWADEE domain Ribonuclease_T2 PF00445.18 RLN95721.1 - 6.5e-27 94.9 0.6 1.4e-26 93.9 0.6 1.5 1 1 0 1 1 1 1 Ribonuclease T2 family Ipi1_N PF12333.8 RLN95722.1 - 0.12 13.0 0.1 6.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation RimM PF01782.18 RLN95723.1 - 0.34 11.2 1.5 14 5.9 0.0 3.1 2 2 1 3 3 3 0 RimM N-terminal domain cNMP_binding PF00027.29 RLN95724.1 - 2.2e-22 78.9 0.0 1.2e-11 44.5 0.1 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain ubiquitin PF00240.23 RLN95724.1 - 8e-10 38.3 0.0 1.6e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RLN95724.1 - 6.8e-06 25.8 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like MBT PF02820.18 RLN95725.1 - 1.2e-14 54.4 10.8 0.029 14.7 0.3 6.3 6 0 0 6 6 6 5 mbt repeat Tudor_4 PF18358.1 RLN95725.1 - 1.5e-08 34.1 11.3 0.0042 16.6 0.4 4.2 3 0 0 3 3 3 3 Histone methyltransferase Tudor domain Tudor-knot PF11717.8 RLN95725.1 - 3.1e-08 33.4 20.3 0.0057 16.5 0.7 5.7 6 0 0 6 6 6 3 RNA binding activity-knot of a chromodomain DUSP PF06337.12 RLN95725.1 - 5.8e-06 26.8 0.0 1.4e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 DUSP domain SAWADEE PF16719.5 RLN95725.1 - 0.00019 21.4 7.5 0.23 11.5 0.6 3.5 3 0 0 3 3 3 3 SAWADEE domain Lipoprotein_21 PF14041.6 RLN95725.1 - 1.6 8.9 3.9 42 4.4 0.1 4.0 4 0 0 4 4 4 0 LppP/LprE lipoprotein SKN1 PF03935.15 RLN95726.1 - 1.2e-60 205.3 25.1 3.7e-27 94.9 4.3 4.9 3 2 0 3 3 3 3 Beta-glucan synthesis-associated protein (SKN1) Nodulin_late PF07127.11 RLN95726.1 - 0.4 11.1 4.0 3.3 8.1 0.6 3.1 2 0 0 2 2 2 0 Late nodulin protein cNMP_binding PF00027.29 RLN95727.1 - 9.4e-32 108.9 0.0 6.6e-11 42.1 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN95727.1 - 8.6e-21 74.3 31.9 2e-08 33.8 5.8 4.8 4 1 0 4 4 4 3 Ion transport protein Ion_trans_2 PF07885.16 RLN95727.1 - 9.5e-15 54.3 21.8 6.2e-08 32.5 4.0 4.9 4 0 0 4 4 4 4 Ion channel GRP PF07172.11 RLN95728.1 - 0.29 11.8 21.9 0.56 10.9 21.9 1.4 1 1 0 1 1 1 0 Glycine rich protein family LPMO_10 PF03067.15 RLN95729.1 - 6.2e-08 33.5 0.0 6.2e-08 33.5 0.0 1.8 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 RLN95729.1 - 0.0053 16.7 0.9 0.043 13.8 0.4 2.2 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 Bromodomain PF00439.25 RLN95731.1 - 2.1e-17 62.9 0.0 4.8e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Bromodomain DNMT1-RFD PF12047.8 RLN95731.1 - 8.4e-07 29.1 0.1 2.5e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain DDT PF02791.17 RLN95731.1 - 0.00032 20.9 0.1 0.00057 20.1 0.1 1.4 1 0 0 1 1 1 1 DDT domain Bromodomain PF00439.25 RLN95734.1 - 1.1e-17 63.8 0.0 4.5e-17 61.9 0.0 2.0 2 0 0 2 2 2 1 Bromodomain WSD PF15613.6 RLN95734.1 - 1.5e-13 51.0 1.2 3.1e-12 46.8 0.5 3.2 2 1 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Auxin_resp PF06507.13 RLN95734.1 - 0.0044 17.2 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 Auxin response factor Guanylin PF02058.15 RLN95735.1 - 0.083 13.4 0.8 0.16 12.4 0.8 1.5 1 0 0 1 1 1 0 Guanylin precursor IBR PF01485.21 RLN95735.1 - 0.13 12.6 4.1 0.22 11.8 1.1 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain FYVE PF01363.21 RLN95735.1 - 3.9 7.7 8.2 11 6.2 8.2 1.7 1 1 0 1 1 1 0 FYVE zinc finger DnaJ PF00226.31 RLN95736.1 - 9.5e-07 28.9 2.3 1.8e-06 28.0 2.3 1.5 1 0 0 1 1 1 1 DnaJ domain RNA_pol_3_Rpc31 PF11705.8 RLN95736.1 - 0.064 13.5 5.6 0.12 12.6 5.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF3985 PF13153.6 RLN95736.1 - 0.38 10.8 3.9 0.77 9.8 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3985) Rap_GAP PF02145.15 RLN95737.1 - 1.5e-42 145.3 0.0 3.1e-42 144.2 0.0 1.5 2 0 0 2 2 2 1 Rap/ran-GAP DUF3384 PF11864.8 RLN95737.1 - 1.8e-26 93.1 0.0 4.2e-25 88.6 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3384) Tuberin PF03542.16 RLN95737.1 - 7e-07 28.7 0.0 0.00069 18.8 0.0 2.7 2 0 0 2 2 2 2 Tuberin Ribosomal_S4 PF00163.19 RLN95739.1 - 0.00011 23.0 1.3 0.00014 22.7 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Band_7 PF01145.25 RLN95740.1 - 3.3e-21 76.1 0.9 6.1e-21 75.2 0.9 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Tim17 PF02466.19 RLN95740.1 - 6.4e-13 49.1 9.7 9.9e-13 48.4 8.8 1.8 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family LicD PF04991.13 RLN95741.1 - 4.3e-19 69.6 1.1 5.4e-15 56.2 0.5 2.1 1 1 0 2 2 2 2 LicD family Terpene_synth PF01397.21 RLN95742.1 - 0.074 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain TIR-like PF10137.9 RLN95742.1 - 0.17 11.9 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain NifQ PF04891.12 RLN95742.1 - 1.1 9.6 4.5 1 9.7 1.0 2.4 2 1 0 2 2 2 0 NifQ PIG-P PF08510.12 RLN95743.1 - 1e-25 90.0 1.6 1e-25 90.0 1.6 1.8 2 0 0 2 2 2 1 PIG-P DPM2 PF07297.12 RLN95743.1 - 0.21 11.9 6.8 0.53 10.6 6.7 1.7 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Sporozoite_P67 PF05642.11 RLN95745.1 - 0.49 8.4 4.3 0.36 8.9 1.3 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen RR_TM4-6 PF06459.12 RLN95745.1 - 1.5 8.6 6.2 2.7 7.7 6.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAD_binding_3 PF01494.19 RLN95746.1 - 1.3e-19 70.7 0.2 3.7e-09 36.3 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 RLN95746.1 - 7.7e-07 28.4 0.0 1.2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 RLN95746.1 - 4.7e-06 25.7 0.0 0.15 10.9 0.0 3.1 3 0 0 3 3 3 3 Tryptophan halogenase DAO PF01266.24 RLN95746.1 - 2e-05 24.4 0.4 6.3e-05 22.7 0.3 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RLN95746.1 - 0.0006 19.1 0.0 0.023 13.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RLN95746.1 - 0.00099 19.3 0.0 0.0028 17.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 RLN95746.1 - 0.0059 15.7 0.6 1.5 7.8 0.3 2.3 1 1 1 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 RLN95746.1 - 0.014 15.9 0.0 0.031 14.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 RLN95746.1 - 0.061 13.6 0.0 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_2 PF00890.24 RLN95746.1 - 0.42 9.6 2.9 1.5 7.8 2.9 2.1 1 1 0 1 1 1 0 FAD binding domain DBR1 PF05011.13 RLN95747.1 - 0.0026 18.2 0.1 0.016 15.7 0.0 1.9 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain TRAP_alpha PF03896.16 RLN95747.1 - 0.068 12.4 1.3 0.079 12.2 1.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cytadhesin_P30 PF07271.11 RLN95747.1 - 0.36 10.4 3.2 0.44 10.1 3.2 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Snf7 PF03357.21 RLN95747.1 - 0.51 9.9 6.1 0.65 9.6 6.1 1.1 1 0 0 1 1 1 0 Snf7 DREV PF05219.12 RLN95748.1 - 3e-45 154.4 0.0 1.8e-27 96.1 0.0 2.0 1 1 1 2 2 2 2 DREV methyltransferase Methyltransf_23 PF13489.6 RLN95748.1 - 1.9e-06 27.8 0.0 3.6e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN95748.1 - 5.2e-06 27.1 0.0 1e-05 26.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN95748.1 - 7.1e-06 26.6 0.0 1.6e-05 25.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 RLN95748.1 - 3.2e-05 23.1 0.0 4.1e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 RLN95748.1 - 3.2e-05 24.5 0.1 0.00034 21.2 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 RLN95748.1 - 0.062 12.3 0.0 0.081 11.9 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase SUI1 PF01253.22 RLN95749.1 - 2.5e-18 66.4 0.1 6.4e-18 65.1 0.1 1.8 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF4637 PF15470.6 RLN95749.1 - 0.012 15.3 3.9 0.026 14.3 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) COX6C PF02937.15 RLN95749.1 - 0.036 14.2 0.1 0.69 10.1 0.0 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc Bunya_RdRp PF04196.12 RLN95749.1 - 0.058 11.8 0.4 0.084 11.2 0.4 1.2 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase eIF-3c_N PF05470.12 RLN95749.1 - 0.11 10.8 2.9 0.14 10.5 2.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DNA_pol_phi PF04931.13 RLN95749.1 - 0.18 9.9 12.3 0.32 9.0 12.3 1.4 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 RLN95749.1 - 0.19 11.0 10.2 0.38 10.0 10.2 1.5 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.12 RLN95749.1 - 2.3 7.5 10.9 3.9 6.8 10.9 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Cwf_Cwc_15 PF04889.12 RLN95749.1 - 6.8 6.3 15.8 0.45 10.2 9.4 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Astro_capsid_p PF12226.8 RLN95749.1 - 7.1 5.7 8.1 11 5.0 8.1 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Voltage_CLC PF00654.20 RLN95750.1 - 7.8e-69 232.6 8.5 7.8e-69 232.6 8.5 2.1 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 RLN95750.1 - 1.3e-06 28.8 0.0 0.00083 19.8 0.0 2.6 2 0 0 2 2 2 2 CBS domain Wbp11 PF09429.10 RLN95751.1 - 0.32 11.4 1.5 0.45 10.9 1.5 1.1 1 0 0 1 1 1 0 WW domain binding protein 11 ANXA2R PF15721.5 RLN95752.1 - 2.8 8.4 5.5 7.5 7.0 5.5 2.0 1 1 0 1 1 1 0 Annexin-2 receptor LMBR1 PF04791.16 RLN95752.1 - 6 5.6 5.3 6.1 5.6 5.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TFIIA PF03153.13 RLN95752.1 - 6.6 6.6 15.2 9.1 6.2 15.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DAGK_cat PF00781.24 RLN95754.1 - 1.9e-25 88.9 0.0 4.9e-25 87.6 0.0 1.8 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SPO22 PF08631.10 RLN95754.1 - 0.096 12.2 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like BSD PF03909.17 RLN95755.1 - 9.1e-07 28.8 1.0 6.8e-06 26.0 0.5 2.3 2 1 0 2 2 2 1 BSD domain CBM64 PF18666.1 RLN95756.1 - 0.098 12.7 0.9 0.3 11.2 0.4 2.1 2 1 0 2 2 2 0 Carbohydrate-binding module 64 Arm PF00514.23 RLN95757.1 - 6.1e-42 140.4 7.0 3.2e-06 27.0 0.0 8.7 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 RLN95757.1 - 1.9e-08 34.2 0.0 0.25 11.4 0.0 4.7 3 1 1 4 4 4 2 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 RLN95757.1 - 1.4e-05 25.4 14.2 0.0081 16.7 0.0 6.1 5 2 3 8 8 8 3 HEAT-like repeat HEAT PF02985.22 RLN95757.1 - 0.00013 21.9 1.8 23 5.6 0.0 6.3 7 0 0 7 7 7 0 HEAT repeat HEAT_2 PF13646.6 RLN95757.1 - 0.0003 21.1 18.8 0.18 12.2 0.4 4.6 1 1 5 6 6 6 6 HEAT repeats WAPL PF07814.13 RLN95757.1 - 0.011 14.5 0.0 2.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Wings apart-like protein regulation of heterochromatin HEAT_PBS PF03130.16 RLN95757.1 - 0.028 15.1 15.1 17 6.5 0.2 6.3 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat UNC45-central PF11701.8 RLN95757.1 - 0.041 13.8 0.3 0.85 9.6 0.1 3.0 4 1 0 4 4 4 0 Myosin-binding striated muscle assembly central Phage_integrase PF00589.22 RLN95758.1 - 0.00035 20.4 0.0 0.00073 19.4 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family DUSP PF06337.12 RLN95759.1 - 9.4e-13 48.6 0.1 1.7e-12 47.8 0.1 1.4 1 0 0 1 1 1 1 DUSP domain C2 PF00168.30 RLN95759.1 - 2.3e-07 31.0 0.1 0.00058 20.1 0.0 2.4 2 0 0 2 2 2 2 C2 domain ASH PF15780.5 RLN95760.1 - 1.4e-05 25.3 0.0 0.13 12.5 0.0 2.6 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 RLN95760.1 - 0.00015 21.9 0.7 0.0015 18.7 0.1 2.4 2 0 0 2 2 2 1 Flagellar-associated PapD-like TMEM131_like PF12371.8 RLN95760.1 - 0.064 13.5 0.0 14 6.0 0.0 2.8 3 0 0 3 3 3 0 Transmembrane protein 131-like EphA2_TM PF14575.6 RLN95761.1 - 0.00077 20.3 0.0 0.0017 19.2 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 RLN95761.1 - 0.0055 16.8 7.1 0.011 15.8 7.0 1.6 1 1 0 1 1 1 1 Podoplanin Yip1 PF04893.17 RLN95761.1 - 0.0097 15.6 0.8 0.016 14.9 0.2 1.6 2 0 0 2 2 2 1 Yip1 domain Amnionless PF14828.6 RLN95761.1 - 0.018 13.9 0.3 0.025 13.4 0.3 1.1 1 0 0 1 1 1 0 Amnionless TMEM154 PF15102.6 RLN95761.1 - 0.023 14.6 0.6 0.055 13.4 0.1 1.9 2 0 0 2 2 2 0 TMEM154 protein family Protocadherin PF08374.11 RLN95761.1 - 0.041 13.9 0.6 0.071 13.1 0.6 1.3 1 0 0 1 1 1 0 Protocadherin Beta-APP PF03494.13 RLN95761.1 - 0.057 13.3 3.2 0.15 11.9 3.2 1.7 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) DUF5305 PF17231.2 RLN95761.1 - 0.084 12.3 2.0 0.12 11.7 0.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF4448 PF14610.6 RLN95761.1 - 0.087 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) RCR PF12273.8 RLN95761.1 - 0.088 13.5 0.0 0.18 12.5 0.0 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red RIFIN PF02009.16 RLN95761.1 - 0.1 12.5 0.3 0.13 12.1 0.3 1.2 1 0 0 1 1 1 0 Rifin LRR_1 PF00560.33 RLN95763.1 - 0.04 14.4 0.9 8.2 7.4 0.4 4.1 2 1 0 2 2 2 0 Leucine Rich Repeat LRR_8 PF13855.6 RLN95763.1 - 0.52 10.1 3.9 0.49 10.2 0.7 2.7 3 1 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 RLN95763.1 - 0.58 10.7 2.9 3 8.4 0.1 3.2 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) TPR_1 PF00515.28 RLN95764.1 - 8e-28 95.1 20.6 1.1e-06 28.1 0.0 6.8 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 RLN95764.1 - 1.5e-22 77.8 20.1 0.00013 21.8 0.0 8.3 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 RLN95764.1 - 5e-21 73.1 28.0 0.00043 20.2 0.0 8.8 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 RLN95764.1 - 7.8e-14 51.1 10.6 1.9e-06 27.4 0.5 6.2 5 2 2 7 7 6 3 TPR repeat TPR_19 PF14559.6 RLN95764.1 - 1e-11 45.2 15.9 0.066 13.7 0.2 6.6 4 2 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 RLN95764.1 - 6.9e-11 42.0 29.4 0.045 14.6 0.0 10.3 7 4 3 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 RLN95764.1 - 3.1e-09 37.3 40.1 1.9e-05 25.2 1.4 8.1 8 2 2 10 10 7 2 Tetratricopeptide repeat ANAPC8 PF04049.13 RLN95764.1 - 5.8e-09 36.1 0.4 2e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_7 PF13176.6 RLN95764.1 - 1.2e-07 31.3 18.0 0.23 11.6 0.0 6.9 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 RLN95764.1 - 1.1e-06 28.9 31.1 9.6e-05 22.6 2.0 6.8 5 2 1 6 6 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 RLN95764.1 - 1.8e-05 24.8 15.1 0.026 14.6 0.1 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN95764.1 - 0.00019 21.5 15.2 1.6 9.3 0.1 7.9 9 0 0 9 9 9 1 Tetratricopeptide repeat ChAPs PF09295.10 RLN95764.1 - 0.0017 17.4 0.0 0.17 10.9 0.0 2.8 1 1 1 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.6 RLN95764.1 - 0.0029 17.6 0.9 0.22 11.6 0.3 3.2 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 RLN95764.1 - 0.0069 16.2 16.5 0.98 9.4 0.1 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN95764.1 - 0.021 15.0 22.4 1.6 9.0 0.3 6.8 3 1 4 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 RLN95764.1 - 0.043 14.5 22.5 15 6.5 0.0 8.5 9 1 0 9 9 9 0 Tetratricopeptide repeat LCE PF14672.6 RLN95764.1 - 0.14 12.8 2.8 0.29 11.8 1.3 2.1 2 0 0 2 2 2 0 Late cornified envelope PPR PF01535.20 RLN95764.1 - 0.19 12.0 2.5 11 6.5 0.1 3.5 4 0 0 4 4 3 0 PPR repeat MtN3_slv PF03083.16 RLN95765.1 - 3.7e-23 81.4 12.4 2e-13 50.1 2.4 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange MtN3_slv PF03083.16 RLN95766.1 - 2.3e-30 104.4 7.4 1.3e-16 60.4 1.4 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Phage_holin_3_1 PF05106.12 RLN95766.1 - 0.029 14.8 1.1 0.067 13.6 1.1 1.6 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) DUF1772 PF08592.11 RLN95766.1 - 0.13 12.5 8.6 0.032 14.5 3.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF5373 PF17343.2 RLN95766.1 - 0.37 10.6 8.2 3.4 7.5 1.5 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5373) DUF456 PF04306.13 RLN95766.1 - 2.9 8.2 10.3 0.095 13.0 1.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF456) Cu2_monooxygen PF01082.20 RLN95767.1 - 0.035 14.3 0.0 0.084 13.1 0.0 1.5 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DDE_Tnp_4 PF13359.6 RLN95769.1 - 1.7e-15 57.1 0.0 2.6e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease IFRD PF05004.13 RLN95770.1 - 2.6e-40 138.4 0.1 4e-40 137.8 0.1 1.3 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) CDPS PF16715.5 RLN95770.1 - 0.027 14.1 0.9 0.054 13.2 0.9 1.5 1 0 0 1 1 1 0 Cyclodipeptide synthase CENP-B_dimeris PF09026.10 RLN95770.1 - 0.03 14.7 0.1 0.4 11.1 0.0 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain EPO_TPO PF00758.18 RLN95770.1 - 0.064 13.3 0.4 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Erythropoietin/thrombopoietin PP2C_C PF07830.13 RLN95770.1 - 0.28 11.6 1.6 4.2 7.9 0.9 2.5 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain S-antigen PF05756.11 RLN95770.1 - 0.69 10.3 3.0 1.6 9.2 3.0 1.6 1 0 0 1 1 1 0 S-antigen protein Rep_fac_C PF08542.11 RLN95771.1 - 1.5e-21 76.6 0.0 3.6e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 RLN95771.1 - 1.9e-13 50.6 0.3 3.7e-11 43.1 0.2 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 RLN95771.1 - 4.2e-13 49.9 0.1 6.6e-13 49.2 0.1 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 RLN95771.1 - 4.5e-07 30.0 0.0 7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 RLN95771.1 - 3.2e-06 27.2 0.0 4.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RLN95771.1 - 5.1e-06 27.0 0.2 0.00046 20.6 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RLN95771.1 - 5.1e-06 26.8 0.2 0.0092 16.3 0.1 2.5 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.21 RLN95771.1 - 2.4e-05 23.8 0.2 0.00034 20.0 0.1 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 RLN95771.1 - 2.7e-05 24.1 0.0 3.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 RLN95771.1 - 7.8e-05 22.6 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RLN95771.1 - 0.00012 22.4 0.7 0.00026 21.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RLN95771.1 - 0.00021 21.1 0.7 0.00051 19.8 0.7 1.6 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 RLN95771.1 - 0.0011 18.0 0.1 0.0024 16.9 0.1 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 RLN95771.1 - 0.0013 18.3 0.2 0.0052 16.4 0.1 2.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 RLN95771.1 - 0.0014 18.4 0.1 0.0045 16.7 0.1 2.0 2 1 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 RLN95771.1 - 0.0015 18.3 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 RLN95771.1 - 0.0036 17.6 0.0 0.01 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_18 PF13238.6 RLN95771.1 - 0.0038 17.8 0.1 0.01 16.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 RLN95771.1 - 0.0045 16.8 0.1 0.0082 16.0 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RLN95771.1 - 0.0062 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 RLN95771.1 - 0.0063 17.0 0.0 0.015 15.8 0.0 1.6 1 1 0 1 1 1 1 ABC transporter TniB PF05621.11 RLN95771.1 - 0.013 14.9 0.1 0.77 9.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein DEAD PF00270.29 RLN95771.1 - 0.015 15.1 0.8 1.4 8.7 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase TIP49 PF06068.13 RLN95771.1 - 0.015 14.5 0.1 0.023 13.9 0.1 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ResIII PF04851.15 RLN95771.1 - 0.017 15.1 0.1 2.5 8.1 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 RLN95771.1 - 0.024 14.4 0.1 0.053 13.3 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 RLN95771.1 - 0.029 14.3 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 RLN95771.1 - 0.033 13.7 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 RLN95771.1 - 0.042 13.8 0.2 0.18 11.7 0.1 2.0 1 1 1 2 2 2 0 NTPase T2SSE PF00437.20 RLN95771.1 - 0.047 12.7 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 RLN95771.1 - 0.084 12.1 0.5 1.2 8.3 0.5 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DNA_pol3_delta PF06144.13 RLN95771.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_33 PF13671.6 RLN95771.1 - 0.11 12.6 0.1 0.19 11.9 0.1 1.4 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 RLN95771.1 - 0.11 11.9 1.0 2.7 7.4 0.1 2.3 1 1 0 2 2 2 0 PhoH-like protein Helicase_RecD PF05127.14 RLN95771.1 - 0.13 12.1 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 Helicase AAA_28 PF13521.6 RLN95771.1 - 0.14 12.4 0.3 0.24 11.6 0.3 1.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 RLN95771.1 - 0.17 12.3 0.0 0.31 11.4 0.0 1.6 1 1 0 1 1 1 0 RNA helicase ADH_zinc_N_2 PF13602.6 RLN95772.1 - 3.1e-18 67.1 0.0 3.7e-17 63.6 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 RLN95772.1 - 1e-11 44.9 0.0 2.9e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN95772.1 - 4.5e-09 36.2 0.0 2.1e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Eno-Rase_NADH_b PF12242.8 RLN95772.1 - 0.0049 16.6 0.3 0.011 15.5 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_16 PF10294.9 RLN95772.1 - 0.0091 15.8 0.1 0.017 14.9 0.1 1.4 1 0 0 1 1 1 1 Lysine methyltransferase BT1 PF03092.16 RLN95773.1 - 1.2e-17 63.4 16.6 2.7e-08 32.5 0.1 3.6 3 1 1 4 4 4 3 BT1 family DUF5353 PF17304.2 RLN95773.1 - 4.3 7.2 12.1 36 4.2 0.1 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5353) DUF4586 PF15239.6 RLN95774.1 - 2.8e-65 221.5 3.4 3.2e-65 221.3 3.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) HTH_54 PF18607.1 RLN95774.1 - 0.15 12.2 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 ParA helix turn helix domain Glyco_hydro_1 PF00232.18 RLN95775.1 - 3.9e-165 549.7 0.0 4.5e-165 549.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 MRC1 PF09444.10 RLN95776.1 - 0.0084 16.6 4.7 0.02 15.4 4.7 1.5 1 0 0 1 1 1 1 MRC1-like domain Acetyltransf_1 PF00583.25 RLN95778.1 - 2e-17 63.5 0.0 2.8e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RLN95778.1 - 8.3e-16 58.1 0.0 1.2e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN95778.1 - 8.4e-14 51.8 0.0 1.3e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 RLN95778.1 - 1.6e-07 31.6 0.0 2.3e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN95778.1 - 2.9e-06 27.2 0.0 4.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 RLN95778.1 - 3.1e-06 27.9 0.0 3.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 RLN95778.1 - 0.00027 21.0 0.0 0.00081 19.5 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 RLN95778.1 - 0.0012 18.9 0.2 0.0049 17.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 RLN95778.1 - 0.01 16.0 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 RLN95778.1 - 0.062 13.3 0.0 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase GNAT_acetyltr_2 PF13718.6 RLN95778.1 - 0.09 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 FYVE PF01363.21 RLN95780.1 - 4.7e-08 33.0 9.7 4.7e-08 33.0 9.7 2.0 2 0 0 2 2 2 1 FYVE zinc finger GAF_2 PF13185.6 RLN95780.1 - 9.7e-05 22.7 0.1 0.00033 20.9 0.1 1.9 1 0 0 1 1 1 1 GAF domain Siva PF05458.12 RLN95780.1 - 0.23 11.1 5.0 0.58 9.8 5.0 1.6 1 0 0 1 1 1 0 Cd27 binding protein (Siva) FYVE_2 PF02318.16 RLN95780.1 - 0.97 9.7 9.0 0.99 9.6 7.4 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger zf-piccolo PF05715.13 RLN95780.1 - 5.2 7.3 8.8 19 5.5 8.8 1.9 1 1 0 1 1 1 0 Piccolo Zn-finger zf-B_box PF00643.24 RLN95780.1 - 5.9 7.1 9.0 1 9.5 4.9 1.8 2 0 0 2 2 2 0 B-box zinc finger Acetyltransf_1 PF00583.25 RLN95781.1 - 3.9e-14 52.9 0.0 5.5e-14 52.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RLN95781.1 - 2.1e-13 50.3 0.0 3.3e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN95781.1 - 9.9e-11 41.9 0.0 1.7e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN95781.1 - 2.3e-06 27.5 0.0 3.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 RLN95781.1 - 0.0012 18.9 0.2 0.0038 17.3 0.0 1.9 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 RLN95781.1 - 0.0013 18.9 0.0 0.0036 17.4 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Mrr_cat PF04471.12 RLN95781.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease Phytase-like PF13449.6 RLN95781.1 - 0.17 11.8 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Esterase-like activity of phytase 7tm_7 PF08395.12 RLN95782.1 - 0.2 10.8 3.6 0.26 10.4 3.5 1.2 1 1 0 1 1 1 0 7tm Chemosensory receptor Oxidored_q2 PF00420.24 RLN95782.1 - 0.32 10.7 5.1 0.52 10.0 0.4 2.4 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L SAYSvFN PF10260.9 RLN95782.1 - 0.37 10.8 0.2 0.37 10.8 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) DUF4407 PF14362.6 RLN95782.1 - 1 8.7 2.6 1.6 8.0 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF485 PF04341.12 RLN95782.1 - 1.7 8.7 8.2 0.33 10.9 4.3 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF485 DUF2207 PF09972.9 RLN95782.1 - 5.6 5.6 6.0 3.9 6.1 0.2 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Drc1-Sld2 PF11719.8 RLN95783.1 - 7.3 6.0 12.3 21 4.5 12.3 1.6 1 1 0 1 1 1 0 DNA replication and checkpoint protein Peptidase_M24 PF00557.24 RLN95784.1 - 2.9e-06 27.1 0.1 4.6e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 RLN95784.1 - 0.0022 18.6 0.0 0.0051 17.5 0.0 1.7 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Creatinase_N_2 PF16189.5 RLN95784.1 - 0.077 13.1 0.4 0.18 11.9 0.1 1.8 2 1 0 2 2 2 0 Creatinase/Prolidase N-terminal domain Asparaginase PF00710.20 RLN95785.1 - 2.9e-57 193.3 0.0 4.3e-57 192.8 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 RLN95785.1 - 1.3e-28 99.5 0.1 2.3e-28 98.7 0.1 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain DUF1754 PF08555.10 RLN95786.1 - 0.00021 22.1 2.4 0.00021 22.1 2.4 2.0 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Ccdc124 PF06244.12 RLN95787.1 - 5.5e-23 81.9 1.5 5.5e-23 81.9 1.5 2.7 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 DENN PF02141.21 RLN95788.1 - 4e-36 124.7 0.0 7.5e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain AalphaY_MDB PF04611.12 RLN95788.1 - 0.03 14.3 0.0 0.071 13.1 0.0 1.6 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region PAN_4 PF14295.6 RLN95789.1 - 1.6e-15 56.8 28.4 1.5e-09 37.6 3.8 3.8 3 0 0 3 3 3 2 PAN domain PAN_2 PF08276.11 RLN95789.1 - 0.00049 20.2 14.6 0.13 12.4 3.9 2.8 2 0 0 2 2 2 2 PAN-like domain NBP1 PF08537.10 RLN95792.1 - 0.082 12.3 3.6 0.19 11.1 2.8 1.9 1 1 1 2 2 2 0 Fungal Nap binding protein NBP1 OSTbeta PF15048.6 RLN95792.1 - 0.13 12.4 1.1 0.37 10.9 0.0 2.2 3 0 0 3 3 3 0 Organic solute transporter subunit beta protein eIF3_subunit PF08597.10 RLN95792.1 - 0.22 11.4 5.8 0.34 10.8 4.7 1.8 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit Conotoxin PF02950.17 RLN95792.1 - 0.56 11.3 2.2 0.8 10.8 0.1 2.2 2 0 0 2 2 2 0 Conotoxin Glyco_hydro_3 PF00933.21 RLN95793.1 - 4.6e-57 193.8 0.0 7.2e-57 193.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN95793.1 - 1.7e-34 119.6 0.0 3e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RLN95793.1 - 2.6e-10 40.3 0.2 4.9e-10 39.4 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PKD PF00801.20 RLN95793.1 - 0.0088 15.9 0.3 0.035 14.0 0.1 2.0 2 0 0 2 2 2 1 PKD domain DUF2336 PF10098.9 RLN95793.1 - 0.041 13.4 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) Homeobox_KN PF05920.11 RLN95794.1 - 1.3e-25 89.0 4.8 4.6e-17 61.6 0.1 3.0 3 0 0 3 3 3 2 Homeobox KN domain Homeodomain PF00046.29 RLN95794.1 - 1.9e-11 43.6 0.1 5.2e-06 26.2 0.1 2.5 2 0 0 2 2 2 2 Homeodomain Ad_cyc_g-alpha PF08509.11 RLN95794.1 - 0.16 11.7 0.6 13 5.6 0.1 3.1 2 0 0 2 2 2 0 Adenylate cyclase G-alpha binding domain PhyH PF05721.13 RLN95795.1 - 7.9e-08 32.8 0.0 2.1e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Peptidase_M14 PF00246.24 RLN95798.1 - 1.7e-12 47.7 0.0 3.4e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 RLN95798.1 - 1.9e-11 44.3 0.4 9.5e-11 42.0 0.0 2.3 3 0 0 3 3 3 1 Cytosolic carboxypeptidase N-terminal domain Ion_trans_2 PF07885.16 RLN95799.1 - 7.3e-10 38.7 4.3 1.5e-09 37.7 4.3 1.5 1 0 0 1 1 1 1 Ion channel SK_channel PF03530.14 RLN95799.1 - 0.00014 21.8 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 Calcium-activated SK potassium channel Ion_trans PF00520.31 RLN95799.1 - 0.0031 16.8 0.6 0.0056 15.9 0.6 1.4 1 0 0 1 1 1 1 Ion transport protein UQ_con PF00179.26 RLN95800.1 - 2.3e-18 66.2 0.9 1.5e-12 47.4 0.6 2.9 2 1 0 2 2 2 2 Ubiquitin-conjugating enzyme Macoilin PF09726.9 RLN95800.1 - 2.8 6.4 7.6 3.1 6.2 7.6 1.0 1 0 0 1 1 1 0 Macoilin family EamA PF00892.20 RLN95801.1 - 6.8e-36 123.5 43.7 2.2e-13 50.6 15.8 3.7 3 1 0 3 3 3 3 EamA-like transporter family TPT PF03151.16 RLN95801.1 - 0.0044 16.4 28.5 0.0083 15.5 2.4 3.8 2 2 1 4 4 4 3 Triose-phosphate Transporter family Gram_pos_anchor PF00746.21 RLN95801.1 - 1.1 9.2 0.0 1.1 9.2 0.0 4.1 5 0 0 5 5 5 0 LPXTG cell wall anchor motif MPS-4 PF17523.2 RLN95801.1 - 5.5 7.2 10.6 3.5 7.8 0.2 3.4 3 0 0 3 3 3 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 NPR1_like_C PF12313.8 RLN95802.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 NPR1/NIM1 like defence protein C terminal Sod_Fe_C PF02777.18 RLN95802.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, C-terminal domain EamA PF00892.20 RLN95803.1 - 1.8e-24 86.5 37.1 4.6e-14 52.8 10.1 4.1 3 1 0 4 4 4 4 EamA-like transporter family DUF4229 PF14012.6 RLN95803.1 - 0.13 12.4 6.0 1.5 8.9 0.8 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) FA_hydroxylase PF04116.13 RLN95804.1 - 5.3e-17 62.4 18.3 5.3e-17 62.4 18.3 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily APG9 PF04109.16 RLN95805.1 - 2e-146 488.8 6.0 2.4e-146 488.6 6.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Telomerase_RBD PF12009.8 RLN95805.1 - 0.036 14.2 0.7 0.088 12.9 0.7 1.7 1 0 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain Pkinase PF00069.25 RLN95806.1 - 5.6e-36 124.3 0.0 7.4e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN95806.1 - 2e-17 63.4 0.0 3.6e-17 62.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN95806.1 - 3.3e-07 30.5 0.1 2.2e-06 27.8 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN95806.1 - 0.00033 20.1 0.0 0.00047 19.6 0.0 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN95806.1 - 0.0016 17.3 0.0 0.0023 16.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 RLN95806.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain POT1 PF02765.17 RLN95807.1 - 2.1e-15 56.8 0.4 3.7e-10 39.8 0.0 2.6 3 0 0 3 3 3 2 Telomeric single stranded DNA binding POT1/CDC13 Sugar_tr PF00083.24 RLN95807.1 - 0.0003 19.8 0.1 0.00038 19.5 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter AAA PF00004.29 RLN95808.1 - 1.8e-10 41.3 0.1 6.3e-10 39.6 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RLN95808.1 - 4.3e-06 27.3 0.2 0.00011 22.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 RLN95808.1 - 5.9e-06 26.3 0.1 0.00089 19.2 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 RLN95808.1 - 3.8e-05 24.0 0.3 0.001 19.4 0.0 3.3 3 1 0 3 3 2 1 AAA domain AAA_14 PF13173.6 RLN95808.1 - 4.9e-05 23.4 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RLN95808.1 - 8.9e-05 22.9 0.5 0.0058 17.0 0.0 3.5 4 0 0 4 4 4 1 AAA ATPase domain AAA_33 PF13671.6 RLN95808.1 - 0.00013 22.1 0.0 0.00091 19.4 0.0 2.6 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 RLN95808.1 - 0.00015 21.6 0.1 0.051 13.3 0.0 3.4 4 0 0 4 4 4 1 AAA domain RuvB_N PF05496.12 RLN95808.1 - 0.0002 21.1 0.0 0.00048 19.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RLN95808.1 - 0.00039 20.4 0.0 0.0035 17.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 RLN95808.1 - 0.00097 18.5 0.0 0.0021 17.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 RLN95808.1 - 0.0029 17.3 0.0 0.0093 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 RLN95808.1 - 0.0047 17.4 2.0 0.055 14.0 0.0 3.4 4 0 0 4 4 3 1 ABC transporter AAA_25 PF13481.6 RLN95808.1 - 0.0048 16.5 0.1 0.95 9.0 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 RLN95808.1 - 0.0092 16.2 1.8 0.027 14.7 0.0 2.7 3 0 0 3 3 1 1 AAA domain RNA_helicase PF00910.22 RLN95808.1 - 0.012 16.0 0.0 0.079 13.4 0.0 2.3 2 0 0 2 2 2 0 RNA helicase RsgA_GTPase PF03193.16 RLN95808.1 - 0.015 15.2 0.0 0.32 10.9 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 RLN95808.1 - 0.023 15.2 0.1 0.13 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 RLN95808.1 - 0.03 14.7 0.0 0.12 12.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 RLN95808.1 - 0.036 13.6 0.0 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 RLN95808.1 - 0.05 13.3 0.0 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 RLN95808.1 - 0.054 13.0 0.1 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_assoc_2 PF16193.5 RLN95808.1 - 0.06 13.7 0.0 0.24 11.8 0.0 2.1 1 0 0 1 1 1 0 AAA C-terminal domain IstB_IS21 PF01695.17 RLN95808.1 - 0.061 13.0 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 RLN95808.1 - 0.094 12.7 0.0 0.28 11.2 0.0 1.8 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 RLN95808.1 - 0.11 12.4 0.1 2.2 8.2 0.0 3.0 4 0 0 4 4 3 0 NACHT domain NB-ARC PF00931.22 RLN95808.1 - 0.14 11.3 0.1 0.8 8.8 0.0 2.3 3 0 0 3 3 3 0 NB-ARC domain Costars PF14705.6 RLN95809.1 - 1.2e-22 79.9 0.3 1.3e-22 79.8 0.3 1.0 1 0 0 1 1 1 1 Costars Apolipo_F PF15148.6 RLN95810.1 - 0.11 11.9 0.4 0.15 11.6 0.4 1.2 1 0 0 1 1 1 0 Apolipoprotein F Mito_carr PF00153.27 RLN95813.1 - 8e-64 211.6 0.3 1.2e-20 73.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 RLN95813.1 - 3.4e-12 46.6 2.6 9.9e-08 32.3 0.2 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN95813.1 - 9.3e-07 28.3 9.0 0.00014 21.5 0.1 4.1 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 RLN95813.1 - 1.8e-06 27.7 0.3 0.021 14.7 0.0 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN95813.1 - 4.4e-06 25.9 7.3 0.0018 17.7 0.1 4.6 5 0 0 5 5 5 2 EF hand EF-hand_5 PF13202.6 RLN95813.1 - 0.0061 16.0 0.6 0.0061 16.0 0.6 3.2 4 0 0 4 4 4 1 EF hand Caleosin PF05042.13 RLN95813.1 - 0.065 13.1 0.1 4.4 7.2 0.1 2.4 2 0 0 2 2 2 0 Caleosin related protein EF-hand_9 PF14658.6 RLN95813.1 - 0.12 12.8 0.0 0.39 11.1 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain ATP-synt PF00231.19 RLN95814.1 - 2e-77 260.6 1.3 2.3e-77 260.5 1.3 1.0 1 0 0 1 1 1 1 ATP synthase Peptidase_MA_2 PF13485.6 RLN95814.1 - 0.06 13.0 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase MA superfamily Arm PF00514.23 RLN95816.1 - 4.3e-06 26.6 21.6 0.43 10.7 0.1 7.9 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 RLN95816.1 - 0.11 12.5 0.4 7.2 6.7 0.0 3.1 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain PEHE PF15275.6 RLN95816.1 - 0.28 11.8 3.3 4 8.1 0.2 3.0 3 0 0 3 3 3 0 PEHE domain rhaM PF05336.13 RLN95816.1 - 0.42 10.7 5.8 0.94 9.6 5.8 1.5 1 0 0 1 1 1 0 L-rhamnose mutarotase DUF4407 PF14362.6 RLN95816.1 - 4.9 6.4 12.8 3.9 6.7 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pkinase_Tyr PF07714.17 RLN95817.1 - 2.6e-47 161.3 0.0 9.6e-43 146.3 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN95817.1 - 1.1e-42 146.2 0.0 5.5e-39 134.1 0.0 2.4 3 0 0 3 3 3 2 Protein kinase domain APH PF01636.23 RLN95817.1 - 0.0011 18.9 0.0 0.0011 18.9 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN95817.1 - 0.0049 15.7 0.0 0.008 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN95817.1 - 0.018 14.3 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 RLN95817.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.20 RLN95817.1 - 0.24 10.7 0.2 2.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Ecdysteroid kinase Kdo PF06293.14 RLN95817.1 - 0.89 8.9 3.3 0.39 10.0 0.1 2.0 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family CTD_bind PF04818.13 RLN95818.1 - 5.5e-05 23.9 0.0 0.00014 22.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 RLN95818.1 - 0.022 15.2 0.9 0.022 15.2 0.9 2.9 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 Gon7 PF08738.10 RLN95818.1 - 0.029 14.4 3.0 0.12 12.5 2.9 2.1 1 1 0 1 1 1 0 Gon7 family Pro-rich PF15240.6 RLN95818.1 - 6 7.1 50.0 9.3 6.5 36.8 2.3 2 0 0 2 2 2 0 Proline-rich MoaC PF01967.21 RLN95819.1 - 2.8e-49 166.7 0.1 3.4e-49 166.4 0.1 1.1 1 0 0 1 1 1 1 MoaC family Chorion_S16 PF05836.12 RLN95819.1 - 0.042 14.1 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 Chorion protein S16 DUF5340 PF17275.2 RLN95820.1 - 0.35 11.0 2.7 0.74 10.0 2.7 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5340) zf-PARP PF00645.18 RLN95821.1 - 8.1e-07 29.8 1.6 2.2e-06 28.4 1.6 1.7 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Dimer_Tnp_hAT PF05699.14 RLN95822.1 - 0.011 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Prok_Ub PF14454.6 RLN95822.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic Ubiquitin QSregVF PF13652.6 RLN95823.1 - 0.035 14.1 0.1 0.058 13.4 0.0 1.4 1 1 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor Ank_2 PF12796.7 RLN95824.1 - 5.2e-32 110.3 0.3 1.7e-08 35.0 0.0 6.0 3 2 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN95824.1 - 2.9e-25 88.3 3.6 0.00074 20.0 0.0 7.3 5 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN95824.1 - 4.8e-24 84.1 5.9 1.7e-07 31.4 0.0 6.2 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN95824.1 - 1e-19 68.5 6.7 0.019 15.5 0.0 8.5 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 RLN95824.1 - 7.5e-19 67.3 16.5 0.0022 18.4 0.0 9.6 9 1 1 10 10 10 5 Ankyrin repeat IQ PF00612.27 RLN95824.1 - 1.5e-09 36.8 107.9 0.00017 21.1 0.1 14.2 13 0 0 13 13 13 7 IQ calmodulin-binding motif TPR_2 PF07719.17 RLN95824.1 - 0.045 13.9 2.4 0.38 11.0 2.4 2.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.25 RLN95825.1 - 6.4e-51 173.3 0.0 7.5e-41 140.2 0.0 3.3 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 RLN95825.1 - 1.4e-20 73.7 0.0 1.3e-13 50.9 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 RLN95825.1 - 0.0012 18.2 0.1 0.025 13.9 0.1 2.6 3 0 0 3 3 3 1 Kinase-like FTA2 PF13095.6 RLN95825.1 - 0.017 14.8 0.0 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RLN95825.1 - 0.02 14.8 0.5 0.077 12.9 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Beach PF02138.18 RLN95826.1 - 5.5e-32 111.3 0.0 1.1e-31 110.3 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PQQ_2 PF13360.6 RLN95826.1 - 1.4e-06 28.0 5.9 3.7e-06 26.7 5.9 1.6 1 0 0 1 1 1 1 PQQ-like domain WD40 PF00400.32 RLN95826.1 - 0.00027 21.7 0.1 0.0011 19.8 0.1 2.1 1 0 0 1 1 1 1 WD domain, G-beta repeat Pkinase PF00069.25 RLN95826.1 - 0.039 13.3 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain B12D PF06522.11 RLN95827.1 - 4.4e-14 52.0 0.0 5.8e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit TMEM65 PF10507.9 RLN95828.1 - 2.3e-38 130.5 3.6 2.3e-38 130.5 3.6 1.5 2 0 0 2 2 2 1 Transmembrane protein 65 EF-hand_1 PF00036.32 RLN95828.1 - 0.0003 20.1 0.0 0.0005 19.4 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 RLN95828.1 - 0.041 13.8 0.1 0.087 12.8 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 RLN95828.1 - 0.075 13.5 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 RLN95828.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 EF hand EamA PF00892.20 RLN95829.1 - 0.00032 20.9 2.9 0.00037 20.7 2.9 1.0 1 0 0 1 1 1 1 EamA-like transporter family 7TMR-DISM_7TM PF07695.11 RLN95829.1 - 0.02 14.8 0.5 0.023 14.6 0.5 1.0 1 0 0 1 1 1 0 7TM diverse intracellular signalling EF-hand_6 PF13405.6 RLN95830.1 - 3.9e-15 54.4 2.7 0.013 15.4 0.0 7.4 6 0 0 6 6 6 4 EF-hand domain EF-hand_7 PF13499.6 RLN95830.1 - 1.3e-13 51.2 5.3 0.00036 20.9 0.0 7.7 7 1 1 8 8 8 4 EF-hand domain pair EF-hand_1 PF00036.32 RLN95830.1 - 3.9e-08 32.3 2.7 0.26 10.9 0.0 7.0 8 0 0 8 8 8 3 EF hand EF-hand_8 PF13833.6 RLN95830.1 - 2.3e-07 30.5 1.7 4.2 7.3 0.0 6.9 7 0 0 7 7 7 2 EF-hand domain pair EF-hand_2 PF09068.11 RLN95830.1 - 0.00046 20.3 0.0 0.068 13.3 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 RLN95830.1 - 0.035 13.6 0.0 9.3 5.9 0.0 4.2 4 0 0 4 4 4 0 EF hand EGF_2 PF07974.13 RLN95831.1 - 5.1e-10 39.5 55.3 0.00046 20.5 10.8 6.5 6 0 0 6 6 6 5 EGF-like domain zf-CCCH_2 PF14608.6 RLN95831.1 - 0.47 11.0 0.2 0.47 11.0 0.2 3.3 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Tim17 PF02466.19 RLN95832.1 - 1.9e-06 28.2 0.8 2.7e-06 27.7 0.8 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2723 PF11028.8 RLN95832.1 - 0.019 14.9 0.4 0.027 14.4 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2723) LRR_6 PF13516.6 RLN95834.1 - 4e-17 60.7 7.3 0.00011 22.0 0.2 4.9 4 0 0 4 4 4 3 Leucine Rich repeat LisH_2 PF16045.5 RLN95834.1 - 1.7e-08 33.3 0.0 3e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 LisH Atx10homo_assoc PF09759.9 RLN95834.1 - 0.0052 16.8 0.9 0.091 12.8 0.0 3.3 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain LRR_8 PF13855.6 RLN95834.1 - 0.023 14.5 1.2 0.16 11.8 0.1 2.8 3 1 0 3 3 3 0 Leucine rich repeat FOP_dimer PF09398.10 RLN95834.1 - 0.048 13.9 0.0 0.19 12.0 0.0 2.1 1 0 0 1 1 1 0 FOP N terminal dimerisation domain LRR_4 PF12799.7 RLN95834.1 - 0.074 13.5 0.1 4.1 8.0 0.1 2.7 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) C2 PF00168.30 RLN95835.1 - 1.2e-07 31.9 0.0 7.5e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 C2 domain Podoplanin PF05808.11 RLN95835.1 - 4.1 7.5 5.1 11 6.1 5.1 1.6 1 0 0 1 1 1 0 Podoplanin PQ-loop PF04193.14 RLN95836.1 - 2.9e-33 113.4 13.6 4.6e-19 68.0 5.7 2.6 2 0 0 2 2 2 2 PQ loop repeat Elicitin PF00964.17 RLN95837.1 - 2.7e-24 85.1 23.6 8.1e-16 57.9 5.8 2.9 3 0 0 3 3 3 2 Elicitin PDT PF00800.18 RLN95837.1 - 0.063 13.1 1.6 0.16 11.8 1.5 1.7 1 1 0 1 1 1 0 Prephenate dehydratase Pkinase_Tyr PF07714.17 RLN95838.1 - 1.3e-66 224.5 0.0 1.7e-66 224.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN95838.1 - 2.1e-55 187.9 0.0 2.8e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RLN95838.1 - 0.00057 19.3 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RLN95838.1 - 0.034 13.1 0.0 0.46 9.4 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain HhH-GPD PF00730.25 RLN95840.1 - 3.3e-14 53.2 0.0 6.6e-13 49.1 0.0 2.5 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Acetyltransf_1 PF00583.25 RLN95840.1 - 1.7e-12 47.6 0.0 3.5e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HHH PF00633.23 RLN95840.1 - 3.1e-09 36.2 0.1 9.2e-09 34.7 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif Acetyltransf_10 PF13673.7 RLN95840.1 - 4.3e-07 29.9 0.1 8.3e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NUDIX_4 PF14815.6 RLN95840.1 - 6.7e-07 29.3 0.4 3e-06 27.2 0.1 2.2 2 0 0 2 2 2 1 NUDIX domain Acetyltransf_7 PF13508.7 RLN95840.1 - 7e-07 29.6 0.0 1.4e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN95840.1 - 8.6e-06 25.6 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 RLN95840.1 - 0.0023 17.6 0.0 0.0055 16.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 RLN95840.1 - 0.056 13.6 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HHH_5 PF14520.6 RLN95840.1 - 0.056 14.0 0.3 0.45 11.2 0.0 2.6 3 0 0 3 3 3 0 Helix-hairpin-helix domain Acetyltransf_3 PF13302.7 RLN95840.1 - 0.12 13.0 0.0 0.35 11.5 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RLN95842.1 - 0.0004 20.6 0.0 0.0009 19.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RLN95842.1 - 0.00048 20.1 0.0 0.65 9.9 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN95842.1 - 0.00076 19.9 0.0 0.002 18.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 RLN95842.1 - 0.011 15.8 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Rubredoxin_2 PF18073.1 RLN95843.1 - 5.1e-10 38.9 6.3 7.7e-10 38.3 6.3 1.3 1 0 0 1 1 1 1 Rubredoxin metal binding domain CENP-Q PF13094.6 RLN95843.1 - 0.1 12.8 0.1 0.089 13.0 0.1 1.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit NifU PF01106.17 RLN95843.1 - 0.2 11.8 0.4 0.33 11.1 0.4 1.3 1 0 0 1 1 1 0 NifU-like domain AAA_25 PF13481.6 RLN95844.1 - 2.7e-14 53.2 2.1 3.3e-14 52.9 0.3 2.1 3 0 0 3 3 3 1 AAA domain Lon_C PF05362.13 RLN95844.1 - 1.4e-11 44.3 0.1 2.3e-11 43.6 0.1 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.6 RLN95844.1 - 9.6e-11 41.6 0.0 1.8e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase ATPase PF06745.13 RLN95844.1 - 1.8e-09 37.3 0.8 0.00074 18.9 0.0 3.1 2 1 0 2 2 2 2 KaiC DnaB_C PF03796.15 RLN95844.1 - 9.3e-07 28.4 0.6 5.5e-05 22.6 0.6 2.4 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain Rad51 PF08423.11 RLN95844.1 - 7.6e-05 22.1 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Rad51 AAA_22 PF13401.6 RLN95844.1 - 0.049 13.9 0.2 0.24 11.7 0.2 2.1 1 1 0 1 1 1 0 AAA domain Beta_helix PF13229.6 RLN95845.1 - 0.002 18.0 12.5 0.079 12.8 3.2 2.4 1 1 1 2 2 2 2 Right handed beta helix region Mannosyl_trans3 PF11051.8 RLN95846.1 - 4.2e-23 82.1 0.0 6.3e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative VasI PF11319.8 RLN95846.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion system VasI, EvfG, VC_A0118 Ank_3 PF13606.6 RLN95847.1 - 0.08 13.5 0.4 41 5.2 0.0 3.6 3 1 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 RLN95847.1 - 0.15 12.7 0.1 0.49 11.0 0.1 1.9 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 RLN95848.1 - 5e-27 94.3 5.6 4.5e-06 27.2 0.3 7.0 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN95848.1 - 2.1e-22 78.9 18.5 0.0037 17.5 0.2 12.7 8 3 6 14 14 14 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN95848.1 - 9e-22 77.2 13.8 1.6e-05 25.3 0.3 10.0 8 3 1 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN95848.1 - 8.7e-13 47.2 5.9 41 5.2 0.0 12.4 14 1 1 15 15 15 0 Ankyrin repeat Ank PF00023.30 RLN95848.1 - 0.016 15.7 4.6 99 3.6 0.1 7.6 7 1 0 7 7 7 0 Ankyrin repeat DUF249 PF03158.13 RLN95848.1 - 0.054 13.2 0.3 4.3 7.0 0.0 3.3 4 0 0 4 4 4 0 Multigene family 530 protein Phage_Cox PF10743.9 RLN95848.1 - 0.17 12.0 0.0 3.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Regulatory phage protein cox Ank_4 PF13637.6 RLN95849.1 - 1.9e-32 111.2 19.2 6.4e-06 26.6 0.1 11.1 9 4 0 9 9 9 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN95849.1 - 2.4e-28 98.5 7.4 7.9e-07 29.6 0.1 6.8 2 1 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN95849.1 - 5.8e-23 80.6 22.6 0.081 13.3 0.0 13.7 7 3 7 14 14 14 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN95849.1 - 6.4e-19 66.1 11.5 1.4 9.7 0.0 14.0 14 1 1 15 15 15 4 Ankyrin repeat Ank PF00023.30 RLN95849.1 - 0.0076 16.7 7.3 1.1e+02 3.6 0.1 8.0 9 2 0 9 9 9 0 Ankyrin repeat Ank_2 PF12796.7 RLN95850.1 - 3.4e-26 91.6 2.7 1.6e-16 60.6 0.6 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN95850.1 - 1.2e-18 67.2 7.8 4.8e-11 43.0 0.7 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN95850.1 - 4.4e-13 49.0 13.3 1.6e-06 28.2 0.2 4.1 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 RLN95850.1 - 6.7e-13 48.6 3.6 1.5e-06 28.4 0.2 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN95850.1 - 1.1e-08 34.6 3.2 0.0053 17.2 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Rax2 PF12768.7 RLN95850.1 - 0.1 12.0 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity VWA_3_C PF18571.1 RLN95850.1 - 0.15 11.9 3.9 1.1 9.1 0.1 3.7 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain Cnd2 PF05786.14 RLN95851.1 - 0.08 11.6 0.2 0.08 11.6 0.2 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 Aminotran_1_2 PF00155.21 RLN95852.1 - 4e-42 144.7 0.0 5e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 RLN95852.1 - 0.00019 20.1 0.0 0.00038 19.1 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 RLN95852.1 - 0.00041 19.2 0.0 0.00077 18.3 0.0 1.4 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 RLN95852.1 - 0.0069 15.4 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V NUDIX PF00293.28 RLN95853.1 - 0.00042 20.4 0.2 0.0012 18.9 0.0 1.8 1 1 1 2 2 2 1 NUDIX domain MRP-L46 PF11788.8 RLN95853.1 - 0.0018 19.0 2.6 0.0079 16.9 0.0 2.8 2 1 0 3 3 3 1 39S mitochondrial ribosomal protein L46 FtsX PF02687.21 RLN95854.1 - 0.13 12.7 1.7 2.3 8.8 0.2 2.2 2 0 0 2 2 2 0 FtsX-like permease family DPBB_1 PF03330.18 RLN95856.1 - 2.3e-07 31.0 5.3 3.2e-07 30.5 2.9 2.4 2 1 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 RLN95856.1 - 0.00057 19.7 2.4 0.001 18.9 2.4 1.4 1 0 0 1 1 1 1 Barwin family GPI-anchored PF10342.9 RLN95856.1 - 0.0071 17.1 3.8 0.0096 16.7 0.7 2.5 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DPBB_1 PF03330.18 RLN95857.1 - 3.1e-05 24.2 0.1 0.00013 22.2 0.1 2.1 1 0 0 1 1 1 1 Lytic transglycolase TMEM154 PF15102.6 RLN95857.1 - 0.0044 16.9 3.4 0.0044 16.9 3.4 3.9 1 1 2 3 3 3 1 TMEM154 protein family EphA2_TM PF14575.6 RLN95857.1 - 0.11 13.4 0.1 0.24 12.3 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5305 PF17231.2 RLN95857.1 - 0.15 11.4 1.1 0.2 11.0 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5305) EVC2_like PF12297.8 RLN95860.1 - 0.037 12.7 0.0 0.048 12.4 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein HCV_capsid PF01543.17 RLN95860.1 - 0.082 13.1 0.0 0.38 11.0 0.0 2.0 2 0 0 2 2 2 0 Hepatitis C virus capsid protein Herpes_UL16 PF03044.14 RLN95862.1 - 0.17 11.1 5.0 0.25 10.6 5.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL16/UL94 family Tmemb_9 PF05434.11 RLN95863.1 - 0.0091 15.9 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 TMEM9 ATP-synt_I PF03899.15 RLN95863.1 - 0.069 13.5 0.1 0.098 13.0 0.1 1.2 1 0 0 1 1 1 0 ATP synthase I chain SNARE_assoc PF09335.11 RLN95863.1 - 0.12 12.9 0.0 0.43 11.1 0.1 1.8 2 0 0 2 2 2 0 SNARE associated Golgi protein Ank_2 PF12796.7 RLN95864.1 - 5e-153 498.1 27.2 3.9e-17 62.6 0.1 9.9 1 1 11 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.30 RLN95864.1 - 1.8e-99 322.2 28.5 7.4e-06 26.2 0.1 19.2 18 1 1 19 19 19 19 Ankyrin repeat Ank_3 PF13606.6 RLN95864.1 - 9e-91 286.8 11.4 1.1e-05 25.4 0.1 19.2 19 0 0 19 19 19 19 Ankyrin repeat Ank_4 PF13637.6 RLN95864.1 - 1.6e-90 296.4 12.1 1.5e-10 41.4 0.0 12.5 7 2 4 12 12 12 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN95864.1 - 5e-82 268.9 29.5 7.7e-10 38.8 0.1 15.4 4 4 12 17 17 17 16 Ankyrin repeats (many copies) Herpes_UL36 PF03586.13 RLN95864.1 - 0.0044 16.4 0.0 0.016 14.6 0.0 1.9 1 0 0 1 1 1 1 Herpesvirus UL36 tegument protein Sigma70_r1_2 PF00140.20 RLN95864.1 - 0.098 12.7 0.1 29 4.8 0.0 3.3 3 0 0 3 3 3 0 Sigma-70 factor, region 1.2 DUF2520 PF10728.9 RLN95864.1 - 0.18 11.6 3.5 2.7 7.8 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF2520) DUF937 PF06078.11 RLN95864.1 - 1.3 9.6 9.7 0.87 10.2 0.4 3.7 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF937) VWA_3_C PF18571.1 RLN95864.1 - 5.6 6.9 13.4 4 7.4 0.1 6.2 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain PPR_long PF17177.4 RLN95865.1 - 5.7e-08 32.4 0.8 3.6e-07 29.8 0.3 2.3 1 1 1 2 2 2 1 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 RLN95865.1 - 0.0014 19.1 6.6 0.0063 17.0 1.9 3.3 1 1 1 3 3 3 2 Tetratricopeptide repeat PPR_3 PF13812.6 RLN95865.1 - 0.0018 18.3 0.0 0.0089 16.1 0.0 2.2 3 0 0 3 3 2 1 Pentatricopeptide repeat domain PPR PF01535.20 RLN95865.1 - 0.0034 17.5 0.0 0.63 10.4 0.0 2.8 2 0 0 2 2 2 1 PPR repeat TPR_7 PF13176.6 RLN95865.1 - 0.0065 16.4 0.5 2.9 8.1 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR_2 PF13041.6 RLN95865.1 - 0.0077 16.4 0.0 0.37 11.0 0.0 2.6 2 0 0 2 2 2 1 PPR repeat family TPR_14 PF13428.6 RLN95865.1 - 0.0099 16.6 8.7 1.8 9.6 0.0 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN95865.1 - 0.024 14.5 1.1 1.8 8.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN95865.1 - 0.08 13.2 0.9 2.1 8.7 0.4 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 GST_C PF00043.25 RLN95865.1 - 0.16 12.2 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TPR_16 PF13432.6 RLN95865.1 - 0.18 12.5 4.9 3.8 8.2 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 RLN95865.1 - 0.19 12.5 0.2 0.19 12.5 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN95865.1 - 0.2 12.0 1.5 0.3 11.4 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_8 PF13855.6 RLN95866.1 - 0.00021 21.0 0.4 0.00037 20.2 0.1 1.5 2 0 0 2 2 2 1 Leucine rich repeat PALP PF00291.25 RLN95869.1 - 1e-51 176.1 0.2 4.2e-31 108.4 0.0 2.1 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 RLN95869.1 - 7.1e-38 128.3 0.4 1.1e-24 86.0 0.0 3.3 2 1 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase DUF908 PF06012.12 RLN95870.1 - 2.4e-08 33.8 0.0 2.9e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) D123 PF07065.14 RLN95871.1 - 4.7e-79 265.7 0.0 5.8e-79 265.4 0.0 1.1 1 0 0 1 1 1 1 D123 Adeno_E3_CR2 PF02439.15 RLN95872.1 - 0.0006 19.5 2.5 0.0006 19.5 2.5 1.8 2 0 0 2 2 2 1 Adenovirus E3 region protein CR2 SKG6 PF08693.10 RLN95872.1 - 0.007 15.7 3.5 0.007 15.7 3.5 2.6 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4514 PF14986.6 RLN95872.1 - 0.044 13.7 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) Patched PF02460.18 RLN95872.1 - 0.049 11.7 0.1 0.07 11.2 0.1 1.2 1 0 0 1 1 1 0 Patched family Rax2 PF12768.7 RLN95872.1 - 0.066 12.7 2.8 0.28 10.6 0.0 2.1 2 0 0 2 2 2 0 Cortical protein marker for cell polarity EphA2_TM PF14575.6 RLN95872.1 - 0.12 13.3 0.0 0.34 11.8 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ABC_membrane_2 PF06472.15 RLN95874.1 - 9.5e-85 284.3 4.3 1.3e-84 283.8 4.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 RLN95874.1 - 4.9e-17 62.7 0.0 1.2e-16 61.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN95874.1 - 6.1e-06 25.8 0.1 0.089 12.2 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RLN95874.1 - 0.0025 17.7 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Adeno_IVa2 PF02456.15 RLN95874.1 - 0.011 14.6 0.0 0.028 13.2 0.0 1.6 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_23 PF13476.6 RLN95874.1 - 0.039 14.4 0.0 0.082 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RLN95874.1 - 0.14 12.7 0.0 0.35 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2227 PF09988.9 RLN95875.1 - 0.0072 16.2 2.1 0.019 14.9 2.1 1.7 1 0 0 1 1 1 1 Uncharacterized metal-binding protein (DUF2227) TMEM238 PF15125.6 RLN95875.1 - 0.065 13.4 7.6 0.6 10.3 1.4 2.9 2 0 0 2 2 2 0 TMEM238 protein family NUDIX PF00293.28 RLN95876.1 - 1.3e-12 47.9 0.1 1.8e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain Aldo_ket_red PF00248.21 RLN95877.1 - 2.3e-65 220.7 0.0 2.6e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 RLN95878.1 - 5.4e-65 219.5 0.0 6.1e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2777 PF10949.8 RLN95878.1 - 0.21 11.2 0.0 0.45 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) Iso_dh PF00180.20 RLN95879.1 - 1.2e-63 215.4 0.0 1.6e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Solute_trans_a PF03619.16 RLN95880.1 - 8.3e-79 264.8 16.6 9.5e-79 264.6 16.6 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Aldo_ket_red PF00248.21 RLN95881.1 - 3.4e-62 210.3 0.0 3.8e-62 210.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HECT PF00632.25 RLN95883.1 - 5.8e-62 209.9 0.0 1.8e-61 208.3 0.0 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 RLN95883.1 - 0.003 17.6 2.8 18 5.6 0.0 4.8 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Arm PF00514.23 RLN95884.1 - 2.1e-30 103.8 11.3 0.00024 21.0 0.0 8.3 8 0 0 8 8 8 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN95884.1 - 1.8e-14 53.9 22.0 0.001 19.5 0.4 8.0 6 2 3 9 9 9 5 HEAT-like repeat HEAT PF02985.22 RLN95884.1 - 6.9e-09 35.2 13.9 0.96 9.9 0.0 7.8 8 0 0 8 8 8 3 HEAT repeat NFACT-R_2 PF18297.1 RLN95884.1 - 0.00035 20.7 1.1 41 4.5 0.0 5.0 2 1 3 6 6 6 0 NFACT protein RNA binding domain HEAT_2 PF13646.6 RLN95884.1 - 0.001 19.4 31.9 0.024 15.0 2.7 5.4 2 2 2 5 5 5 2 HEAT repeats Tox-MPTase3 PF15639.6 RLN95884.1 - 0.068 13.0 0.1 3.9 7.3 0.0 3.1 2 1 0 2 2 2 0 Metallopeptidase toxin 3 RPAP1_C PF08620.10 RLN95884.1 - 0.12 12.5 0.0 94 3.2 0.0 3.5 3 0 0 3 3 3 0 RPAP1-like, C-terminal HEAT_PBS PF03130.16 RLN95884.1 - 0.91 10.4 28.5 17 6.4 0.3 7.3 6 1 1 7 7 7 0 PBS lyase HEAT-like repeat Antimicrobial17 PF08129.11 RLN95884.1 - 9.5 6.3 9.2 99 3.0 0.1 4.6 5 0 0 5 5 5 0 Alpha/beta enterocin family Pkinase_Tyr PF07714.17 RLN95886.1 - 1e-41 143.0 0.0 2.2e-41 141.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN95886.1 - 2.2e-38 132.2 0.0 4.8e-38 131.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.23 RLN95886.1 - 3.2e-13 49.2 0.5 0.0076 16.3 0.0 5.8 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat ABC1 PF03109.16 RLN95886.1 - 9.1e-05 22.6 0.0 0.00033 20.8 0.0 2.0 1 0 0 1 1 1 1 ABC1 family Arm_2 PF04826.13 RLN95886.1 - 0.00029 20.4 0.0 0.014 14.8 0.0 2.6 1 1 1 2 2 2 1 Armadillo-like HEAT_EZ PF13513.6 RLN95886.1 - 0.0011 19.5 1.8 0.1 13.1 0.3 3.9 3 0 0 3 3 3 1 HEAT-like repeat Kdo PF06293.14 RLN95886.1 - 0.017 14.5 0.2 0.079 12.3 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HEAT PF02985.22 RLN95886.1 - 0.021 15.0 0.1 30 5.2 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat Acyl-CoA_dh_N PF02771.16 RLN95886.1 - 0.045 14.4 0.1 44 4.8 0.0 4.7 4 1 1 5 5 5 0 Acyl-CoA dehydrogenase, N-terminal domain eIF3_N PF09440.10 RLN95886.1 - 0.047 14.1 5.2 0.3 11.5 6.0 1.9 2 0 0 2 2 1 0 eIF3 subunit 6 N terminal domain APH PF01636.23 RLN95886.1 - 0.74 9.7 3.4 0.74 9.7 0.0 2.6 3 1 0 3 3 3 0 Phosphotransferase enzyme family Abhydrolase_6 PF12697.7 RLN95888.1 - 1e-05 26.2 0.0 0.00026 21.7 0.0 2.0 1 1 0 2 2 2 1 Alpha/beta hydrolase family MMR_HSR1 PF01926.23 RLN95889.1 - 9.6e-11 41.8 0.0 2.3e-09 37.3 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 RLN95889.1 - 1.2e-05 24.8 0.0 1.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 RLN95889.1 - 2.1e-05 24.5 0.6 0.00067 19.6 0.0 3.1 2 1 1 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 RLN95889.1 - 0.0004 20.9 0.1 0.0012 19.4 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 RLN95889.1 - 0.0071 16.1 0.2 0.032 14.0 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 RLN95889.1 - 0.022 14.6 2.4 2.7 7.7 0.1 3.4 2 1 2 4 4 4 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 RLN95889.1 - 0.027 14.5 4.1 5.7 7.0 0.1 3.8 3 1 1 4 4 4 0 Dynamin family AAA_16 PF13191.6 RLN95889.1 - 0.04 14.3 0.1 0.096 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.6 RLN95889.1 - 0.053 13.9 0.1 0.16 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 RLN95889.1 - 0.095 12.2 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_28 PF13521.6 RLN95889.1 - 0.15 12.3 0.3 4 7.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 RLN95889.1 - 0.21 11.9 0.3 1.9 8.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 RLN95889.1 - 0.72 10.3 3.9 2.4 8.6 3.9 2.0 1 1 0 1 1 1 0 AAA domain PHD PF00628.29 RLN95890.1 - 2.5e-38 129.7 95.3 3.4e-06 26.9 6.3 13.9 12 1 2 14 14 14 9 PHD-finger FYRN PF05964.14 RLN95890.1 - 1.2e-17 63.5 0.1 2.7e-17 62.3 0.1 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus Bromodomain PF00439.25 RLN95890.1 - 1.7e-16 60.0 0.1 3.8e-16 58.9 0.1 1.6 1 0 0 1 1 1 1 Bromodomain SET PF00856.28 RLN95890.1 - 7.4e-14 52.5 4.1 7.9e-14 52.4 0.0 3.3 4 0 0 4 4 4 1 SET domain zf-HC5HC2H PF13771.6 RLN95890.1 - 2.2e-06 27.8 6.7 2.2e-06 27.8 6.7 7.6 7 0 0 7 7 7 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 RLN95890.1 - 4.3e-06 26.8 8.8 4.3e-06 26.8 8.8 6.2 6 0 0 6 6 6 2 PHD-zinc-finger like domain FYRC PF05965.14 RLN95890.1 - 0.00035 20.7 0.0 0.004 17.3 0.0 2.8 2 1 0 2 2 2 1 F/Y rich C-terminus NADH_B2 PF14813.6 RLN95891.1 - 0.049 13.4 0.2 0.12 12.2 0.2 1.6 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Ank_2 PF12796.7 RLN95892.1 - 1.4e-43 147.4 21.1 4.6e-10 39.9 0.2 4.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN95892.1 - 5.5e-36 122.5 9.7 5.4e-10 39.6 0.1 7.9 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN95892.1 - 1.9e-34 117.2 17.5 6.8e-12 45.4 0.2 6.1 2 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN95892.1 - 4e-29 97.4 8.8 0.00012 22.2 0.1 8.6 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 RLN95892.1 - 3.3e-28 96.9 17.1 0.00011 22.5 1.0 8.0 8 0 0 8 8 8 7 Ankyrin repeat NifQ PF04891.12 RLN95892.1 - 0.015 15.7 0.8 0.026 14.9 0.8 1.4 1 0 0 1 1 1 0 NifQ Biotin_carb_C PF02785.19 RLN95892.1 - 0.015 15.4 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain SnoaL_2 PF12680.7 RLN95893.1 - 0.048 14.3 0.0 0.051 14.2 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain SH PF01445.17 RLN95894.1 - 0.06 13.3 0.5 0.22 11.5 0.5 2.0 1 0 0 1 1 1 0 Viral small hydrophobic protein Peptidase_U4 PF03419.13 RLN95894.1 - 7.3 5.8 14.0 4.3 6.5 2.5 2.7 2 1 0 2 2 2 0 Sporulation factor SpoIIGA OPA3 PF07047.12 RLN95895.1 - 0.047 13.5 0.3 0.085 12.6 0.3 1.4 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) ELMO_CED12 PF04727.13 RLN95896.1 - 5.2e-19 69.0 0.0 8.8e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family AATase PF07247.12 RLN95897.1 - 6e-06 25.1 0.0 6.9e-06 24.9 0.0 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase DUF2220 PF09983.9 RLN95897.1 - 0.15 11.4 0.1 0.34 10.2 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) Condensation PF00668.20 RLN95898.1 - 0.0081 14.9 0.0 0.0094 14.7 0.0 1.1 1 0 0 1 1 1 1 Condensation domain EF-hand_7 PF13499.6 RLN95899.1 - 5.3e-05 23.6 0.4 9.3e-05 22.8 0.4 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RLN95899.1 - 0.00051 19.8 0.2 0.024 14.5 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN95899.1 - 0.00058 19.2 0.1 0.42 10.3 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RLN95899.1 - 0.0018 18.0 0.1 0.37 10.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain eIF3m_C_helix PF18005.1 RLN95899.1 - 0.11 12.2 0.2 0.23 11.2 0.2 1.6 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix SHIPPO-rpt PF07004.12 RLN95900.1 - 1.2e-06 29.2 33.3 0.23 12.5 0.1 9.7 10 0 0 10 10 10 6 Sperm-tail PG-rich repeat CAP_N PF01213.19 RLN95900.1 - 1.2 8.5 4.2 2.6 7.4 4.2 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DHHC PF01529.20 RLN95901.1 - 8.9e-05 22.6 2.4 0.00016 21.8 2.4 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase LapA_dom PF06305.11 RLN95901.1 - 0.072 12.9 0.4 0.072 12.9 0.4 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain CCT PF06203.14 RLN95902.1 - 5.5e-08 32.7 2.4 9.9e-08 31.9 2.4 1.4 1 0 0 1 1 1 1 CCT motif CBFB_NFYA PF02045.15 RLN95902.1 - 0.0073 16.9 1.0 0.022 15.4 1.0 1.8 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Zn_dep_PLPC PF00882.18 RLN95902.1 - 0.087 12.8 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Zinc dependent phospholipase C TPR_2 PF07719.17 RLN95906.1 - 0.0019 18.1 0.7 6.8 7.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN95906.1 - 0.002 17.8 0.1 0.076 12.7 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 RLN95906.1 - 0.0021 18.3 0.0 0.085 13.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN95906.1 - 0.0032 17.2 0.9 11 6.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN95906.1 - 0.052 13.8 1.1 1.2 9.5 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN95906.1 - 0.14 12.4 0.4 0.47 10.7 0.0 2.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 CCDC-167 PF15188.6 RLN95910.1 - 3.8 7.9 8.4 0.33 11.3 0.8 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 COMM_domain PF07258.14 RLN95911.1 - 0.05 13.7 0.0 16 5.7 0.0 3.1 3 0 0 3 3 3 0 COMM domain Tup_N PF08581.10 RLN95911.1 - 0.96 9.8 10.6 32 4.9 0.0 4.3 4 0 0 4 4 4 0 Tup N-terminal DUF5320 PF17253.2 RLN95911.1 - 1.8 9.7 10.5 2.9 9.0 0.6 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5320) CCDC-167 PF15188.6 RLN95911.1 - 7.6 7.0 20.0 0.32 11.3 1.0 3.6 4 0 0 4 4 4 0 Coiled-coil domain-containing protein 167 PRCC PF10253.9 RLN95912.1 - 0.75 10.5 5.0 0.17 12.7 1.0 1.9 1 1 1 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting CCDC-167 PF15188.6 RLN95912.1 - 1.5 9.2 5.0 0.27 11.6 0.8 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 MID_MedPIWI PF18296.1 RLN95913.1 - 0.13 12.0 0.9 0.2 11.5 0.1 1.8 2 0 0 2 2 2 0 MID domain of medPIWI Pkinase_Tyr PF07714.17 RLN95915.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase AGOG PF09171.10 RLN95915.1 - 0.041 13.2 0.1 0.069 12.5 0.1 1.3 1 0 0 1 1 1 0 N-glycosylase/DNA lyase tRNA-synt_2 PF00152.20 RLN95916.1 - 1.5e-81 273.9 0.0 1.8e-81 273.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RLN95916.1 - 4.2e-08 33.1 0.2 9.5e-08 31.9 0.2 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 RLN95916.1 - 0.0074 15.8 0.1 0.067 12.7 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) Exo_endo_phos PF03372.23 RLN95917.1 - 4.7e-29 101.6 0.0 2.5e-28 99.2 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family fn3 PF00041.21 RLN95917.1 - 1.2e-12 48.0 0.0 2.3e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RLN95917.1 - 0.0023 18.5 0.0 0.0048 17.4 0.0 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Mito_carr PF00153.27 RLN95918.1 - 6.7e-64 211.9 2.2 1.1e-20 73.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CKS PF01111.19 RLN95919.1 - 1.1e-31 108.9 3.1 2.7e-25 88.4 0.4 2.2 2 0 0 2 2 2 2 Cyclin-dependent kinase regulatory subunit Cwf_Cwc_15 PF04889.12 RLN95920.1 - 0.00035 20.4 13.5 0.025 14.3 7.1 2.2 2 0 0 2 2 2 2 Cwf15/Cwc15 cell cycle control protein Spt5_N PF11942.8 RLN95920.1 - 0.0011 19.9 10.1 0.17 12.9 3.5 2.6 2 0 0 2 2 2 2 Spt5 transcription elongation factor, acidic N-terminal PBP1_TM PF14812.6 RLN95920.1 - 0.021 15.2 8.8 0.021 15.2 8.8 2.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 RLN95920.1 - 0.031 13.9 7.0 0.57 9.8 0.6 2.3 2 0 0 2 2 2 0 FAM176 family TFIIA PF03153.13 RLN95920.1 - 0.54 10.2 10.5 0.98 9.3 10.5 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RXT2_N PF08595.11 RLN95920.1 - 4.6 7.2 7.2 0.61 10.1 1.8 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.12 RLN95920.1 - 5.1 6.3 16.4 0.51 9.6 11.5 1.7 2 0 0 2 2 2 0 NOA36 protein CENP-B_dimeris PF09026.10 RLN95920.1 - 9 6.8 15.4 24 5.4 15.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-RING_2 PF13639.6 RLN95921.1 - 1.1e-09 38.4 9.8 1.1e-09 38.4 9.8 2.6 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 RLN95921.1 - 3.2e-07 30.5 9.0 1.5e-06 28.4 9.0 2.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 RLN95921.1 - 2.8e-05 24.1 3.2 2.8e-05 24.1 3.2 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 RLN95921.1 - 5.8e-05 22.9 7.6 5.8e-05 22.9 7.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN95921.1 - 0.00034 20.3 8.0 0.00034 20.3 8.0 3.0 3 1 0 3 3 3 1 RING-like zinc finger zf-RING_UBOX PF13445.6 RLN95921.1 - 0.0014 18.6 3.1 0.0014 18.6 3.1 2.4 2 1 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN95921.1 - 0.028 14.4 7.7 0.028 14.4 7.7 2.5 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RLN95921.1 - 0.54 10.1 20.6 0.053 13.4 13.3 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RLN95921.1 - 1.4 9.2 8.2 0.23 11.7 2.9 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 RLN95921.1 - 1.7 8.9 14.3 2.4 8.4 8.0 3.3 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 RLN95921.1 - 5 7.1 14.9 0.05 13.5 6.3 2.2 2 1 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN95922.1 - 1.5e-10 41.3 5.2 6e-10 39.3 5.2 2.2 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RLN95922.1 - 1.4e-09 38.0 3.2 4.3e-09 36.5 3.2 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 RLN95922.1 - 2.8e-05 23.9 3.0 2.8e-05 23.9 3.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN95922.1 - 5.4e-05 23.0 5.5 0.00028 20.7 5.5 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RLN95922.1 - 0.00012 22.1 1.1 0.00012 22.1 1.1 2.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 RLN95922.1 - 0.00012 22.0 1.9 0.00025 21.0 0.3 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 RLN95922.1 - 0.00017 21.5 2.2 0.00063 19.6 2.2 2.1 1 0 0 1 1 1 1 zinc-RING finger domain PX PF00787.24 RLN95922.1 - 0.0012 18.9 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 PX domain zf-RING_11 PF17123.5 RLN95922.1 - 0.011 15.5 6.9 0.011 15.5 6.9 3.3 3 1 0 3 3 3 0 RING-like zinc finger zf-Nse PF11789.8 RLN95922.1 - 0.015 15.1 1.3 0.038 13.8 1.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 RLN95922.1 - 0.024 14.5 2.3 0.066 13.1 2.3 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 RLN95922.1 - 0.036 13.9 6.3 0.33 10.8 6.4 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RLN95922.1 - 0.069 13.3 5.2 0.14 12.4 2.9 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 RLN95922.1 - 5.1 7.3 11.2 5.3 7.3 6.7 3.0 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_2 PF13639.6 RLN95923.1 - 3.4e-11 43.3 8.1 3.4e-11 43.3 8.1 2.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 RLN95923.1 - 6.7e-09 35.9 8.7 2e-08 34.4 8.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RLN95923.1 - 2.6e-06 27.2 7.1 8.4e-06 25.6 7.1 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN95923.1 - 1.8e-05 24.4 10.1 0.00011 21.9 10.1 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RLN95923.1 - 4.6e-05 23.4 1.2 0.00013 21.9 1.2 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 RLN95923.1 - 6.5e-05 22.9 2.8 6.5e-05 22.9 2.8 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 RLN95923.1 - 0.00012 21.7 8.3 0.00012 21.7 8.3 3.3 3 1 0 3 3 3 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 RLN95923.1 - 0.00084 19.2 5.9 0.0037 17.1 5.9 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN95923.1 - 0.0072 16.3 5.7 0.0072 16.3 5.7 2.1 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RLN95923.1 - 0.0076 16.1 6.5 0.072 13.0 6.5 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 PX PF00787.24 RLN95923.1 - 0.05 13.6 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 PX domain zf-C3HC4_4 PF15227.6 RLN95923.1 - 0.24 11.6 6.8 0.14 12.3 3.1 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 RLN95923.1 - 0.52 10.5 12.9 2.2 8.5 7.9 3.1 2 1 0 2 2 2 0 FANCL C-terminal domain zf-Nse PF11789.8 RLN95923.1 - 8.6 6.3 8.1 1.3 8.9 3.0 2.2 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit NMT PF01233.19 RLN95924.1 - 2.7e-75 251.6 0.0 6.4e-75 250.4 0.0 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 RLN95924.1 - 4.4e-67 225.7 0.0 7.4e-67 224.9 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Pet191_N PF10203.9 RLN95924.1 - 1.4e-20 73.3 6.5 2.4e-20 72.6 6.5 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Acetyltransf_9 PF13527.7 RLN95924.1 - 0.061 13.4 0.0 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Peroxidase_2 PF01328.17 RLN95924.1 - 0.071 13.6 0.1 0.19 12.3 0.0 1.7 2 0 0 2 2 2 0 Peroxidase, family 2 Acetyltransf_1 PF00583.25 RLN95924.1 - 0.087 13.1 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family NMT_C PF02799.15 RLN95925.1 - 2.3e-80 269.0 0.3 3.7e-80 268.4 0.3 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 RLN95925.1 - 3.8e-77 257.6 0.1 5.3e-76 253.9 0.0 2.1 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 RLN95925.1 - 0.0065 16.5 0.1 0.047 13.8 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RLN95925.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family VWA_2 PF13519.6 RLN95927.1 - 0.0046 17.6 0.0 0.014 16.1 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 RLN95927.1 - 0.014 15.6 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 von Willebrand factor type A domain SMRP1 PF15181.6 RLN95928.1 - 0.014 15.0 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Spermatid-specific manchette-related protein 1 Proteasome PF00227.26 RLN95929.1 - 8.6e-42 142.8 0.1 1.2e-41 142.4 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RLN95929.1 - 1.4e-11 43.9 0.2 2.4e-11 43.1 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DDE_1 PF03184.19 RLN95930.1 - 1.4e-22 80.2 0.0 2.1e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN95930.1 - 3.2e-11 43.1 0.0 9.1e-11 41.6 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 RLN95930.1 - 0.0062 16.2 2.2 0.014 15.1 1.3 2.0 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain DUF3006 PF11213.8 RLN95930.1 - 0.057 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) AGT PF11440.8 RLN95930.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 DNA alpha-glucosyltransferase Ras PF00071.22 RLN95931.1 - 1.4e-42 145.0 0.8 3.2e-42 143.9 0.8 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RLN95931.1 - 9.8e-23 80.7 0.3 2.8e-22 79.2 0.0 1.8 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN95931.1 - 1.9e-07 30.7 0.0 3.6e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RLN95931.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 RLN95931.1 - 0.014 14.7 0.0 0.26 10.6 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region ANAPC4_WD40 PF12894.7 RLN95932.1 - 6.1e-08 32.9 0.1 0.0001 22.5 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 RLN95932.1 - 0.092 11.0 0.1 0.14 10.5 0.1 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 RLN95932.1 - 0.11 13.4 0.7 24 6.0 0.0 3.4 2 1 1 3 3 3 0 WD domain, G-beta repeat Neuropep_like PF15161.6 RLN95932.1 - 0.11 12.2 0.8 0.39 10.4 0.1 2.3 2 0 0 2 2 2 0 Neuropeptide-like Pkinase PF00069.25 RLN95933.1 - 1.9e-47 161.8 0.0 2.8e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN95933.1 - 4e-18 65.6 0.0 6.4e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RLN95933.1 - 0.018 14.0 0.0 0.027 13.4 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 RLN95933.1 - 0.077 12.3 0.3 0.12 11.7 0.3 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_TTP_12 PF16461.5 RLN95933.1 - 0.31 10.7 1.3 0.5 10.1 1.3 1.2 1 0 0 1 1 1 0 Lambda phage tail tube protein, TTP HSP70 PF00012.20 RLN95934.1 - 2.5e-123 412.4 11.6 4.5e-122 408.3 11.6 2.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN95934.1 - 0.00042 19.2 0.0 0.001 18.0 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein LSM PF01423.22 RLN95935.1 - 2.3e-11 43.2 0.4 0.00016 21.3 0.2 2.2 2 0 0 2 2 2 2 LSM domain F-box_4 PF15966.5 RLN95935.1 - 0.0019 18.0 0.1 0.005 16.7 0.1 1.7 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 RLN95935.1 - 0.0021 17.9 3.0 0.0024 17.8 1.3 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RLN95935.1 - 0.0026 17.6 1.0 0.0071 16.2 1.0 1.8 1 0 0 1 1 1 1 F-box domain adh_short_C2 PF13561.6 RLN95937.1 - 2.4e-44 151.6 0.1 4.6e-44 150.7 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RLN95937.1 - 4.4e-35 120.9 0.9 1.4e-34 119.3 0.9 1.9 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RLN95937.1 - 4.7e-08 33.2 0.5 1.2e-07 31.8 0.5 1.7 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 RLN95937.1 - 0.11 11.4 0.2 0.22 10.5 0.2 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3683 PF12447.8 RLN95937.1 - 0.15 12.2 0.2 0.15 12.2 0.2 3.3 2 2 2 4 4 4 0 Protein of unknown function (DUF3683) NmrA PF05368.13 RLN95937.1 - 0.17 11.4 2.1 0.7 9.4 0.5 2.6 2 0 0 2 2 2 0 NmrA-like family PRR22 PF15776.5 RLN95937.1 - 0.78 9.0 2.7 1.3 8.3 2.7 1.3 1 0 0 1 1 1 0 Proline-rich protein family 22 ISN1 PF06437.11 RLN95938.1 - 9.1e-66 222.4 0.0 1.2e-65 222.1 0.0 1.1 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Rtf2 PF04641.12 RLN95938.1 - 0.00044 19.7 5.6 0.00065 19.1 5.6 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger Sec62 PF03839.16 RLN95938.1 - 1.4 8.4 4.6 2 7.8 4.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4736 PF15883.5 RLN95938.1 - 2 8.1 4.2 7.1 6.3 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) RabGAP-TBC PF00566.18 RLN95939.1 - 9e-37 126.8 0.0 1.4e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_2 PF12796.7 RLN95939.1 - 1.7e-26 92.6 1.3 1.5e-08 35.1 0.0 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN95939.1 - 2.5e-21 75.4 1.8 9.6e-05 22.6 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN95939.1 - 3.8e-19 68.8 4.5 4.9e-07 30.2 0.3 4.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN95939.1 - 1.3e-17 62.1 3.4 0.0023 18.2 0.1 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 RLN95939.1 - 2.1e-11 43.7 5.8 0.032 14.7 0.2 4.9 5 0 0 5 5 5 3 Ankyrin repeat TFIIA PF03153.13 RLN95942.1 - 0.28 11.1 3.3 0.34 10.8 3.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Palm_thioest PF02089.15 RLN95947.1 - 9e-47 159.9 0.0 1.1e-46 159.6 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 RLN95947.1 - 0.0028 17.2 0.0 0.0051 16.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 RLN95947.1 - 0.0055 16.4 0.0 0.01 15.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_2 PF01674.18 RLN95947.1 - 0.014 14.9 0.0 0.032 13.8 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 2) LIDHydrolase PF10230.9 RLN95947.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 RLN95947.1 - 0.18 11.0 0.1 1.3 8.2 0.1 2.0 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Aa_trans PF01490.18 RLN95948.1 - 1.6e-41 142.3 15.3 2.4e-41 141.8 15.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2976 PF11190.8 RLN95948.1 - 1.2 9.0 10.3 1.9 8.3 1.5 4.3 4 1 0 4 4 4 0 Protein of unknown function (DUF2976) Phage_head_fibr PF11133.8 RLN95950.1 - 0.16 11.3 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Head fiber protein Bac_rhamnosid6H PF17389.2 RLN95954.1 - 3.8e-11 42.8 0.2 1.5e-08 34.3 0.1 2.2 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain GDE_C PF06202.14 RLN95954.1 - 0.0065 15.4 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.18 RLN95954.1 - 0.011 14.6 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Trehalase LicD PF04991.13 RLN95956.1 - 0.00028 21.1 0.0 0.024 14.8 0.0 2.3 2 0 0 2 2 2 2 LicD family LicD PF04991.13 RLN95957.1 - 6.2e-05 23.3 0.2 0.016 15.3 0.1 2.2 2 0 0 2 2 2 2 LicD family LicD PF04991.13 RLN95958.1 - 0.00016 21.9 0.0 0.029 14.5 0.0 2.3 2 0 0 2 2 2 2 LicD family HECT PF00632.25 RLN95959.1 - 3.5e-95 319.0 0.1 5.3e-95 318.4 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 RLN95959.1 - 1.1e-37 129.9 27.3 1.6e-35 122.8 0.3 5.8 4 1 1 5 5 5 3 Domain of Unknown Function (DUF913) UBM PF14377.6 RLN95959.1 - 9.7e-21 72.5 13.8 9.8e-07 28.0 0.4 4.2 3 0 0 3 3 3 3 Ubiquitin binding region DUF908 PF06012.12 RLN95959.1 - 1.2e-12 48.0 0.0 1.2e-12 48.0 0.0 3.5 4 0 0 4 4 4 1 Domain of Unknown Function (DUF908) UBA PF00627.31 RLN95959.1 - 3e-06 27.0 0.0 1.4e-05 24.9 0.0 2.3 1 0 0 1 1 1 1 UBA/TS-N domain STAG PF08514.11 RLN95960.1 - 2.6e-28 98.2 0.8 1.2e-27 96.1 0.1 2.6 2 0 0 2 2 2 1 STAG domain Cnd1 PF12717.7 RLN95960.1 - 0.008 16.2 2.8 0.02 14.9 0.1 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RLN95960.1 - 0.013 15.7 0.4 17 6.0 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 RLN95960.1 - 0.073 13.5 0.1 0.69 10.3 0.0 2.8 2 1 0 2 2 2 0 HEAT repeats Rotamase PF00639.21 RLN95960.1 - 0.31 12.0 2.6 3.2 8.8 0.3 3.3 2 0 0 2 2 2 0 PPIC-type PPIASE domain DEAD PF00270.29 RLN95961.1 - 2.3e-44 151.2 0.1 4.9e-44 150.2 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN95961.1 - 1.4e-30 105.9 0.2 4.8e-29 100.9 0.2 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 RLN95961.1 - 0.00091 19.5 0.0 0.0032 17.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain Glyco_hydro_3_C PF01915.22 RLN95962.1 - 3.9e-50 170.6 0.0 6.2e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 RLN95962.1 - 4.8e-37 128.0 0.0 7.4e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 RLN95962.1 - 1.1e-13 51.1 0.0 2.7e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain TPR_1 PF00515.28 RLN95963.1 - 3.1e-23 80.6 14.0 1.3e-05 24.8 0.0 8.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 RLN95963.1 - 7.4e-16 56.9 39.3 1.3e-05 24.9 0.1 10.8 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_11 PF13414.6 RLN95963.1 - 1.9e-11 43.4 1.0 0.011 15.3 0.0 6.0 4 2 2 6 6 6 3 TPR repeat TPR_9 PF13371.6 RLN95963.1 - 6.3e-11 42.3 50.1 1.6e-05 25.0 5.7 9.6 7 2 4 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.6 RLN95963.1 - 5.2e-09 35.6 19.1 3.3 8.1 0.0 9.3 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 RLN95963.1 - 1.4e-05 25.7 59.5 0.00084 19.9 6.8 8.5 6 2 1 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 RLN95963.1 - 7.6e-05 22.9 44.8 0.00053 20.2 0.7 8.9 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN95963.1 - 0.00025 21.2 0.5 3 8.4 0.0 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat NTP_transf_2 PF01909.23 RLN95963.1 - 0.0024 18.1 0.0 0.016 15.5 0.0 2.4 2 0 0 2 2 2 1 Nucleotidyltransferase domain TPR_19 PF14559.6 RLN95963.1 - 0.0053 17.2 30.4 0.022 15.3 0.1 8.0 6 4 4 10 10 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN95963.1 - 0.007 16.6 5.1 0.14 12.4 1.8 3.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 RLN95963.1 - 0.13 13.0 0.1 0.13 13.0 0.1 8.3 10 0 0 10 10 8 0 Tetratricopeptide repeat Sulfatase_C PF14707.6 RLN95963.1 - 0.35 11.6 3.9 1.5 9.6 3.9 2.1 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase NARP1 PF12569.8 RLN95963.1 - 0.47 9.3 0.0 0.47 9.3 0.0 4.5 5 1 0 5 5 4 0 NMDA receptor-regulated protein 1 CxC6 PF18721.1 RLN95965.1 - 0.76 10.1 18.1 0.85 9.9 6.0 2.9 1 1 1 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases RRM_7 PF16367.5 RLN95966.1 - 0.0012 18.9 0.0 0.0032 17.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif RRM_1 PF00076.22 RLN95966.1 - 0.037 13.9 0.7 0.27 11.1 0.0 2.7 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Big_2 PF02368.18 RLN95966.1 - 0.22 11.5 1.8 0.37 10.7 0.1 2.1 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) zf-RING_2 PF13639.6 RLN95967.1 - 5.9e-06 26.5 5.7 5.9e-06 26.5 5.7 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN95967.1 - 7.7e-06 25.7 4.0 7.7e-06 25.7 4.0 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN95967.1 - 8.2e-06 25.7 2.3 2e-05 24.4 2.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 RLN95967.1 - 0.00021 21.5 2.5 0.00021 21.5 2.5 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 RLN95967.1 - 0.0024 17.6 0.5 0.0073 16.0 0.5 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 RLN95967.1 - 0.0028 17.5 5.8 0.0071 16.2 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN95967.1 - 0.0036 17.3 2.4 0.0089 16.0 2.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger PHD PF00628.29 RLN95967.1 - 0.052 13.4 2.1 0.15 12.0 2.1 1.8 1 0 0 1 1 1 0 PHD-finger PX PF00787.24 RLN95967.1 - 0.064 13.2 0.1 0.17 11.9 0.1 1.8 1 1 0 1 1 1 0 PX domain zf-ANAPC11 PF12861.7 RLN95967.1 - 0.091 12.8 0.7 0.25 11.4 0.7 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 RLN95967.1 - 0.097 12.7 3.6 0.27 11.3 3.6 1.8 1 0 0 1 1 1 0 Zinc-finger zf-C3HC4_3 PF13920.6 RLN95967.1 - 1.4 8.8 5.7 4.4 7.2 5.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 RLN95967.1 - 1.5 8.5 7.0 0.7 9.6 3.4 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Zn-ribbon_8 PF09723.10 RLN95967.1 - 5.7 7.1 7.3 1 9.5 0.9 2.5 2 0 0 2 2 2 0 Zinc ribbon domain DNA_RNApol_7kD PF03604.13 RLN95967.1 - 9.9 5.9 6.8 22 4.8 3.0 2.6 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit SSF PF00474.17 RLN95968.1 - 9e-08 31.4 15.6 9e-08 31.4 15.6 1.8 1 1 0 1 1 1 1 Sodium:solute symporter family Suc_Fer-like PF06999.12 RLN95969.1 - 4e-14 52.9 0.0 5.4e-10 39.5 0.0 2.1 1 1 1 2 2 2 2 Sucrase/ferredoxin-like Tub PF01167.18 RLN95970.1 - 8.1e-50 169.8 0.0 2e-49 168.6 0.0 1.6 1 1 0 1 1 1 1 Tub family zf-RING_2 PF13639.6 RLN95970.1 - 2.8e-09 37.2 11.5 2.8e-09 37.2 11.5 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN95970.1 - 3.6e-08 33.1 10.1 3.6e-08 33.1 10.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN95970.1 - 5.2e-07 29.4 14.4 6.2e-07 29.2 9.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN95970.1 - 1.5e-05 24.7 11.6 1.5e-05 24.7 11.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN95970.1 - 0.00011 22.1 8.7 0.00038 20.4 6.4 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 RLN95970.1 - 0.00048 20.4 9.2 0.00048 20.4 9.2 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 RLN95970.1 - 0.00053 19.8 11.5 0.0013 18.6 8.5 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 RLN95970.1 - 0.058 13.3 5.5 0.16 11.9 5.5 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 RLN95970.1 - 0.084 12.9 16.0 0.022 14.7 11.4 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-Di19 PF05605.12 RLN95970.1 - 0.098 13.0 0.1 0.098 13.0 0.1 3.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-ANAPC11 PF12861.7 RLN95970.1 - 0.25 11.4 5.9 0.051 13.6 2.1 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 RLN95970.1 - 0.5 10.6 14.5 0.44 10.7 11.1 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FYVE PF01363.21 RLN95970.1 - 0.65 10.2 14.7 3.8 7.7 14.8 2.1 1 1 0 1 1 1 0 FYVE zinc finger Baculo_IE-1 PF05290.11 RLN95970.1 - 1 9.3 7.3 1.1 9.2 6.3 1.5 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zinc-ribbons_6 PF07191.12 RLN95970.1 - 4.7 7.3 12.6 5.4 7.1 7.0 2.4 2 0 0 2 2 2 0 zinc-ribbons zf-RING_10 PF16685.5 RLN95970.1 - 9.5 6.4 10.2 18 5.6 8.4 2.3 1 1 1 2 2 2 0 zinc RING finger of MSL2 F420_oxidored PF03807.17 RLN95971.1 - 0.003 18.1 0.0 0.0095 16.5 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 RLN95971.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Prephenate dehydrogenase Pkinase_Tyr PF07714.17 RLN95972.1 - 2.4e-43 148.3 0.0 6.1e-43 147.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RLN95972.1 - 3.3e-42 144.7 0.0 9.9e-42 143.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Ank_2 PF12796.7 RLN95972.1 - 7.9e-07 29.6 0.0 2.5e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN95972.1 - 2.3e-05 24.6 0.1 7.2e-05 23.0 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN95972.1 - 9e-05 22.9 0.1 0.0004 20.9 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN95972.1 - 0.00068 19.9 0.0 0.0062 16.9 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 RLN95972.1 - 0.0015 18.9 0.1 0.1 13.1 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat UPF0154 PF03672.13 RLN95973.1 - 0.054 13.5 1.8 8.2 6.5 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) Tom5 PF10642.9 RLN95973.1 - 0.1 12.6 7.3 0.38 10.8 0.8 3.8 4 0 0 4 4 4 0 Mitochondrial import receptor subunit or translocase NUFIP1 PF10453.9 RLN95973.1 - 0.54 10.1 2.8 3.1 7.7 0.1 2.5 3 0 0 3 3 3 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) RSB_motif PF16294.5 RLN95973.1 - 1.2 9.5 8.3 43 4.4 0.2 4.0 4 0 0 4 4 4 0 RNSP1-SAP18 binding (RSB) motif Ribonuclease_T2 PF00445.18 RLN95975.1 - 1e-25 91.0 0.2 1.4e-25 90.6 0.2 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family GlcNAc PF11397.8 RLN95976.1 - 1.3e-07 31.4 0.4 2.6e-07 30.5 0.4 1.5 1 1 0 1 1 1 1 Glycosyltransferase (GlcNAc) Ceramidase PF05875.12 RLN95977.1 - 1.9e-53 181.6 24.5 3.4e-50 170.9 18.6 2.1 1 1 1 2 2 2 2 Ceramidase Mito_carr PF00153.27 RLN95978.1 - 9.1e-36 121.7 3.3 4.8e-14 52.0 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein PTAC PF06130.12 RLN95979.1 - 0.0035 17.5 0.7 0.86 9.8 0.1 2.7 2 0 0 2 2 2 2 Phosphate propanoyltransferase Peptidase_A22B PF04258.13 RLN95980.1 - 1e-55 189.3 0.8 1.6e-55 188.6 0.8 1.2 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 RLN95980.1 - 9.4e-05 22.4 0.2 0.0054 16.7 0.0 2.7 3 0 0 3 3 3 1 PA domain CcmH PF03918.14 RLN95980.1 - 0.085 12.1 0.0 0.22 10.8 0.0 1.7 1 0 0 1 1 1 0 Cytochrome C biogenesis protein SPP PF06550.11 RLN95980.1 - 2.4 7.6 9.0 0.29 10.5 3.4 2.2 2 0 0 2 2 2 0 Signal-peptide peptidase, presenilin aspartyl protease EF-hand_1 PF00036.32 RLN95981.1 - 0.13 11.8 0.0 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 EF hand ANAPC3 PF12895.7 RLN95983.1 - 0.0059 16.8 5.2 0.015 15.5 0.8 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 RLN95983.1 - 0.041 14.6 3.1 0.41 11.3 3.1 2.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN95983.1 - 0.09 12.6 2.5 2.2 8.3 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN95983.1 - 0.15 12.4 11.7 1.2 9.5 2.9 4.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN95983.1 - 0.41 10.9 17.0 0.23 11.6 0.2 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF4501 PF14946.6 RLN95985.1 - 0.14 12.2 0.7 0.21 11.6 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) Herpes_capsid PF06112.11 RLN95985.1 - 6.3 6.8 14.9 10 6.2 14.9 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein CBAH PF02275.18 RLN95986.1 - 4.4e-24 85.7 0.0 9.3e-24 84.6 0.0 1.6 1 1 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family CBS PF00571.28 RLN95988.1 - 1.8e-20 73.1 0.5 6.3e-11 42.6 0.3 2.2 2 0 0 2 2 2 2 CBS domain PRC PF05239.16 RLN95988.1 - 0.0047 17.0 0.7 0.03 14.4 0.1 2.2 2 0 0 2 2 2 1 PRC-barrel domain GAF_2 PF13185.6 RLN95988.1 - 0.0061 16.9 0.0 0.0096 16.2 0.0 1.2 1 0 0 1 1 1 1 GAF domain HARE-HTH PF05066.13 RLN95988.1 - 0.12 12.7 0.1 0.91 10.0 0.0 2.3 1 1 1 2 2 2 0 HB1, ASXL, restriction endonuclease HTH domain zf-CCCH PF00642.24 RLN95989.1 - 0.011 15.6 0.6 2.3 8.2 0.1 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nsp1_C PF05064.13 RLN95989.1 - 0.099 12.5 0.9 0.18 11.6 0.9 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region Bcr-Abl_Oligo PF09036.10 RLN95989.1 - 0.28 11.2 3.5 0.13 12.2 0.4 2.0 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain HCNGP PF07818.13 RLN95990.1 - 9.1e-26 90.4 0.0 1.5e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 HCNGP-like protein SAP130_C PF16014.5 RLN95990.1 - 0.2 10.7 4.1 0.27 10.3 4.1 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus RCC1 PF00415.18 RLN95991.1 - 1.1e-20 74.0 10.6 1.5e-10 41.5 0.2 4.2 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN95991.1 - 2.1e-10 40.1 10.8 1.7e-05 24.5 0.9 3.5 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat SAP PF02037.27 RLN95991.1 - 0.0042 16.8 1.0 0.0071 16.1 0.0 1.9 2 0 0 2 2 2 1 SAP domain Peptidase_S9_N PF02897.15 RLN95995.1 - 1.8e-09 36.9 0.1 2.6e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain RabGAP-TBC PF00566.18 RLN95996.1 - 0.0081 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Kinesin PF00225.23 RLN95997.1 - 2.9e-94 315.7 0.7 2.9e-94 315.7 0.7 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RLN95997.1 - 1e-44 152.1 0.1 2.2e-44 151.0 0.1 1.6 1 0 0 1 1 1 1 Microtubule binding MPS2 PF17060.5 RLN95997.1 - 0.056 12.7 5.7 1.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Monopolar spindle protein 2 DUF724 PF05266.14 RLN95997.1 - 0.1 12.4 0.2 0.1 12.4 0.2 3.4 3 1 0 4 4 4 0 Protein of unknown function (DUF724) YabA PF06156.13 RLN95997.1 - 0.45 11.2 14.5 18 6.0 1.9 4.5 3 2 0 3 3 3 0 Initiation control protein YabA DUF4201 PF13870.6 RLN95997.1 - 2.5 7.8 16.1 0.037 13.8 1.8 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) KLRAQ PF10205.9 RLN95997.1 - 4.9 7.4 12.3 0.22 11.8 4.2 2.7 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein XhlA PF10779.9 RLN95997.1 - 7.5 6.8 6.2 3.4 7.9 0.8 2.8 2 0 0 2 2 2 0 Haemolysin XhlA DUF1664 PF07889.12 RLN95997.1 - 9.3 6.3 7.3 2.9 7.9 2.1 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) ANAPC3 PF12895.7 RLN95998.1 - 0.035 14.3 0.0 0.061 13.6 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 IF-2B PF01008.17 RLN95998.1 - 0.15 11.2 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Initiation factor 2 subunit family TPR_19 PF14559.6 RLN95999.1 - 1.5e-11 44.6 0.4 3.5e-07 30.6 0.0 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN95999.1 - 1e-08 34.6 0.3 0.0011 18.9 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN95999.1 - 3.3e-08 33.1 0.4 0.00048 19.8 0.0 2.0 1 1 1 2 2 2 2 TPR repeat TPR_14 PF13428.6 RLN95999.1 - 4.2e-08 33.4 0.1 6.4e-05 23.5 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN95999.1 - 1.6e-07 30.9 0.3 0.00057 19.6 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN95999.1 - 2.2e-07 30.6 0.1 0.0011 19.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 RLN95999.1 - 0.00011 22.6 0.1 0.11 13.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN95999.1 - 0.00014 22.4 0.1 0.036 14.7 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN95999.1 - 0.00023 20.9 0.2 0.081 12.8 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN95999.1 - 0.00052 19.9 0.1 0.071 13.2 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN95999.1 - 0.00059 20.0 0.0 0.00074 19.7 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 RLN95999.1 - 0.0015 18.8 0.1 0.023 15.0 0.1 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN95999.1 - 0.0022 18.0 0.2 1.1 9.3 0.1 2.1 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 RLN95999.1 - 0.0024 18.1 0.0 1.4 9.5 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.6 RLN95999.1 - 0.049 12.8 0.0 0.18 11.0 0.0 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat HDV_ag PF01517.18 RLN95999.1 - 0.14 11.9 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen ABC_tran PF00005.27 RLN96000.1 - 1.3e-27 97.0 0.0 2.8e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN96000.1 - 1.8e-09 37.9 0.2 2e-07 31.1 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RLN96000.1 - 0.00081 19.2 0.0 0.019 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain RNA_pol_Rpb5_N PF03871.14 RLN96000.1 - 0.042 14.4 0.0 2 9.0 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb5, N-terminal domain DUF4162 PF13732.6 RLN96000.1 - 0.071 13.8 0.1 4.2 8.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) ABC2_membrane_3 PF12698.7 RLN96001.1 - 0.099 11.7 0.9 0.3 10.2 0.9 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein FtsJ PF01728.19 RLN96004.1 - 2.4e-08 34.3 0.0 3.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase RRM_1 PF00076.22 RLN96005.1 - 1.6e-16 59.9 0.3 2.8e-05 23.9 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RLN96005.1 - 5.8e-05 22.9 0.0 0.6 10.0 0.0 3.4 3 0 0 3 3 3 2 Occluded RNA-recognition motif DUF4523 PF15023.6 RLN96005.1 - 0.0039 17.0 0.0 2.8 7.8 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF4523) Ala_racemase_N PF01168.20 RLN96005.1 - 0.022 14.4 0.1 0.54 9.9 0.1 2.2 2 0 0 2 2 2 0 Alanine racemase, N-terminal domain Nup35_RRM PF05172.13 RLN96005.1 - 0.035 14.1 0.0 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF4054 PF13262.6 RLN96005.1 - 0.037 14.1 0.1 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) RRM_9 PF18444.1 RLN96005.1 - 0.038 13.9 0.9 3.3 7.6 0.0 3.2 3 0 0 3 3 3 0 RNA recognition motif Penicillinase_R PF03965.16 RLN96005.1 - 0.073 13.4 1.1 0.15 12.4 1.1 1.5 1 0 0 1 1 1 0 Penicillinase repressor Rdx PF10262.9 RLN96006.1 - 0.0081 16.3 0.0 0.037 14.2 0.0 2.2 1 0 0 1 1 1 1 Rdx family Rep_N PF08724.10 RLN96006.1 - 0.12 12.1 0.4 0.38 10.5 0.2 1.8 2 0 0 2 2 2 0 Rep protein catalytic domain like HSF_DNA-bind PF00447.17 RLN96008.1 - 1e-28 99.8 0.0 1.6e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding ZapB PF06005.12 RLN96008.1 - 0.092 13.2 1.0 0.23 11.9 1.0 1.6 1 0 0 1 1 1 0 Cell division protein ZapB WD40_alt PF14077.6 RLN96008.1 - 0.2 11.5 1.2 0.35 10.8 0.4 1.7 2 0 0 2 2 2 0 Alternative WD40 repeat motif CCT PF06203.14 RLN96009.1 - 5.3e-08 32.8 2.4 9.9e-08 31.9 2.4 1.5 1 0 0 1 1 1 1 CCT motif CBFB_NFYA PF02045.15 RLN96009.1 - 0.0073 16.9 1.0 0.022 15.4 1.0 1.8 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TPR_11 PF13414.6 RLN96014.1 - 0.0038 16.9 0.1 0.11 12.2 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 RLN96014.1 - 0.018 15.4 0.0 0.13 12.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN96014.1 - 0.11 12.4 0.7 13 5.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN96014.1 - 0.11 12.6 0.2 53 4.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DHHC PF01529.20 RLN96018.1 - 4.8e-05 23.5 2.5 7.3e-05 22.9 2.5 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase YjcB PF15940.5 RLN96018.1 - 0.017 15.3 0.1 0.028 14.6 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function CAP_N PF01213.19 RLN96019.1 - 0.85 9.0 5.2 0.94 8.9 4.0 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Vps53_N PF04100.12 RLN96020.1 - 2.2e-102 342.9 2.9 4.5e-102 341.8 2.9 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal Sec6 PF06046.13 RLN96020.1 - 2.9e-10 39.2 0.2 9.7e-07 27.5 0.1 2.8 3 0 0 3 3 3 2 Exocyst complex component Sec6 Vps54_N PF10475.9 RLN96020.1 - 1.1e-08 34.8 4.5 2.9e-08 33.4 4.5 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG7 PF10191.9 RLN96020.1 - 6.2e-06 24.8 4.1 0.00038 18.8 0.0 2.5 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) COG5 PF10392.9 RLN96020.1 - 0.0013 18.9 2.4 0.004 17.3 2.4 1.8 1 0 0 1 1 1 1 Golgi transport complex subunit 5 RINT1_TIP1 PF04437.13 RLN96020.1 - 0.0063 15.5 1.2 0.019 13.8 0.1 2.3 2 1 0 2 2 2 1 RINT-1 / TIP-1 family VPS53_C PF16854.5 RLN96020.1 - 0.0078 16.1 1.9 0.0093 15.9 0.0 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 53 C-terminus SIP1 PF04938.12 RLN96020.1 - 0.03 14.0 2.1 0.21 11.2 1.2 2.9 2 1 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) FUSC PF04632.12 RLN96020.1 - 0.7 8.4 3.8 1 7.8 3.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 RLN96020.1 - 8.5 6.4 6.5 7.1 6.7 1.9 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Fer2_3 PF13085.6 RLN96021.1 - 1.9e-24 85.8 0.0 2.4e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 RLN96021.1 - 0.00035 20.5 0.9 0.00053 19.9 0.9 1.4 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF4461 PF14688.6 RLN96022.1 - 3.3e-65 220.9 0.0 5.6e-65 220.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) DUF4460 PF14687.6 RLN96022.1 - 3.8e-05 23.7 2.7 0.035 14.1 0.0 3.3 3 1 0 3 3 3 2 Domain of unknown function (DUF4460) NAD_binding_10 PF13460.6 RLN96022.1 - 0.048 13.6 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding BIRC6 PF12356.8 RLN96023.1 - 1.5 8.2 4.9 0.59 9.5 1.8 1.8 1 1 1 2 2 2 0 Baculoviral IAP repeat-containing protein 6 Peptidase_M48 PF01435.18 RLN96025.1 - 2.3e-17 63.4 0.2 2.4e-09 37.3 0.0 2.2 1 1 1 2 2 2 2 Peptidase family M48 Reprolysin_4 PF13583.6 RLN96025.1 - 0.0098 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 RLN96025.1 - 0.066 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Zn_peptidase_2 PF04298.12 RLN96025.1 - 0.1 12.0 1.0 0.18 11.2 1.0 1.3 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Peptidase_M10 PF00413.24 RLN96025.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Matrixin Homoserine_dh PF00742.19 RLN96027.1 - 9.4e-54 181.9 0.9 1.8e-53 181.0 0.9 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 RLN96027.1 - 1.1e-12 48.6 0.1 2.4e-12 47.5 0.1 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain LRR_8 PF13855.6 RLN96028.1 - 4.7e-06 26.3 1.7 0.00099 18.8 1.2 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RLN96028.1 - 0.0041 17.5 0.4 0.048 14.1 0.2 2.5 1 1 0 2 2 2 1 Leucine Rich repeats (2 copies) FKBP_C PF00254.28 RLN96029.1 - 4.2e-33 113.5 0.0 7.3e-33 112.8 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase 2OG-FeII_Oxy_2 PF13532.6 RLN96031.1 - 4.8e-15 56.3 0.0 3.8e-14 53.3 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 RLN96031.1 - 0.00058 20.3 0.0 0.0012 19.3 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FYVE PF01363.21 RLN96032.1 - 4.8e-18 65.1 14.4 5.3e-18 64.9 14.4 1.0 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN96032.1 - 0.012 15.8 10.3 0.015 15.5 10.3 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger Baculo_IE-1 PF05290.11 RLN96032.1 - 10 6.1 13.6 1.1e+02 2.7 1.1 2.0 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) PhyH PF05721.13 RLN96033.1 - 1.8e-12 48.0 0.7 1.7e-11 44.8 0.6 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Cupin_2 PF07883.11 RLN96033.1 - 0.15 11.8 0.1 0.77 9.5 0.0 1.9 2 0 0 2 2 2 0 Cupin domain Glyco_hydro_31 PF01055.26 RLN96034.1 - 3.3e-97 326.4 0.3 5.5e-97 325.7 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 RLN96034.1 - 1.9e-28 99.0 0.9 3.4e-28 98.2 0.9 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 RLN96034.1 - 2.2e-10 40.7 0.7 8.6e-10 38.8 0.4 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like CBM_25 PF03423.13 RLN96034.1 - 2.9e-10 40.3 2.9 9.9e-10 38.6 2.9 1.9 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) CBM53 PF16760.5 RLN96034.1 - 2.9e-06 27.8 1.9 9.1e-06 26.2 1.9 1.9 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) 6PGD PF00393.19 RLN96034.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 6-phosphogluconate dehydrogenase, C-terminal domain DUF2043 PF09740.9 RLN96034.1 - 0.15 12.8 0.1 0.42 11.3 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2043) HEAT PF02985.22 RLN96035.1 - 2e-10 40.0 9.7 0.99 9.8 0.0 9.4 10 1 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.6 RLN96035.1 - 8.3e-07 29.4 1.8 2.2 8.9 0.0 6.4 7 0 0 7 7 7 2 HEAT-like repeat HEAT_2 PF13646.6 RLN96035.1 - 2.7e-06 27.7 9.0 0.05 14.0 0.3 7.0 5 2 1 7 7 7 1 HEAT repeats DUF3385 PF11865.8 RLN96035.1 - 0.0002 21.3 0.0 0.00079 19.4 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 RLN96035.1 - 0.022 13.3 4.5 3.7 6.0 0.5 4.4 3 2 0 3 3 3 0 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 RLN96035.1 - 0.17 12.5 0.0 6.4 7.4 0.0 3.4 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region DTW PF03942.15 RLN96036.1 - 3.8e-20 72.5 0.0 6.6e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 DTW domain zf-CCHC PF00098.23 RLN96036.1 - 6.3e-05 22.9 14.9 0.0001 22.2 2.3 3.1 4 0 0 4 4 4 2 Zinc knuckle zf-C2H2_10 PF16588.5 RLN96036.1 - 0.008 15.9 1.1 0.02 14.6 1.1 1.6 1 0 0 1 1 1 1 C2H2 zinc-finger NAD_binding_1 PF00175.21 RLN96037.1 - 1.2e-29 103.1 0.0 3.4e-29 101.7 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 RLN96037.1 - 1.3e-25 89.6 0.0 2.2e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 RLN96037.1 - 1.6e-05 25.1 0.1 0.00041 20.5 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 RLN96037.1 - 0.17 12.1 0.0 6 7.1 0.0 2.2 1 1 1 2 2 2 0 Siderophore-interacting FAD-binding domain ERCC4 PF02732.15 RLN96038.1 - 1e-18 68.0 0.0 2.3e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain Tctex-1 PF03645.13 RLN96041.1 - 5.7e-21 74.7 0.2 1.2e-20 73.7 0.2 1.5 2 0 0 2 2 2 1 Tctex-1 family SlyX PF04102.12 RLN96042.1 - 0.0014 19.2 7.5 0.0014 19.2 7.5 14.4 6 3 7 14 14 14 1 SlyX HOOK PF05622.12 RLN96042.1 - 0.0024 16.1 22.0 0.0024 16.1 22.0 4.3 1 1 2 4 4 4 1 HOOK protein ZapB PF06005.12 RLN96042.1 - 0.055 13.9 0.7 0.055 13.9 0.7 14.7 9 5 4 13 13 13 0 Cell division protein ZapB Ank_2 PF12796.7 RLN96043.1 - 3.9e-19 69.0 0.8 1.3e-12 48.1 0.5 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN96043.1 - 4.3e-17 62.0 0.1 6.6e-05 23.1 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN96043.1 - 3.8e-14 52.9 0.3 0.0004 20.9 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN96043.1 - 1.3e-12 46.7 1.4 0.0045 17.4 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 RLN96043.1 - 4.7e-11 42.6 3.5 0.0036 17.7 0.1 4.7 2 1 2 4 4 4 3 Ankyrin repeat FYVE PF01363.21 RLN96043.1 - 6.1e-08 32.7 15.8 1e-07 32.0 15.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger PDZ PF00595.24 RLN96043.1 - 0.0021 18.4 0.0 0.0052 17.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Strep_SA_rep PF06696.11 RLN96044.1 - 0.45 10.6 5.5 0.87 9.7 5.5 1.5 1 0 0 1 1 1 0 Streptococcal surface antigen repeat Helicase_C PF00271.31 RLN96045.1 - 8.6e-11 42.2 0.0 1.1e-09 38.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 RLN96045.1 - 3.6e-08 33.4 0.0 9.8e-08 32.0 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RLN96045.1 - 4.7e-05 23.7 0.1 0.00036 20.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Nop25 PF09805.9 RLN96045.1 - 0.002 18.6 0.7 0.002 18.6 0.7 3.3 2 1 0 2 2 1 1 Nucleolar protein 12 (25kDa) T2SSE PF00437.20 RLN96045.1 - 0.0033 16.5 0.0 0.0061 15.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.6 RLN96045.1 - 0.0077 16.4 0.5 0.033 14.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 RLN96045.1 - 0.015 15.8 0.3 0.015 15.8 0.3 3.0 2 2 0 2 2 1 0 AAA domain AAA_19 PF13245.6 RLN96045.1 - 0.02 15.2 1.3 0.066 13.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 RLN96045.1 - 0.041 13.2 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 RLN96045.1 - 0.062 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 RLN96045.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Acyltransferase PF01553.21 RLN96046.1 - 0.00045 19.8 0.1 0.12 12.0 0.0 2.3 1 1 1 2 2 2 2 Acyltransferase EGF_2 PF07974.13 RLN96047.1 - 7.8e-06 26.2 8.8 7.8e-06 26.2 8.8 4.8 5 0 0 5 5 5 4 EGF-like domain EGF PF00008.27 RLN96047.1 - 0.0026 18.0 4.4 0.0026 18.0 4.4 5.0 6 0 0 6 6 6 2 EGF-like domain hEGF PF12661.7 RLN96047.1 - 0.053 14.2 7.8 0.053 14.2 7.8 4.8 5 0 0 5 5 5 0 Human growth factor-like EGF SCPU PF05229.15 RLN96047.1 - 0.52 10.7 5.4 0.15 12.5 0.7 2.2 1 1 1 2 2 2 0 Spore Coat Protein U domain Laminin_EGF PF00053.24 RLN96047.1 - 3.7 7.8 36.6 0.45 10.7 12.0 4.1 2 1 1 3 3 3 0 Laminin EGF domain adh_short PF00106.25 RLN96048.1 - 7.2e-08 32.1 0.0 2.5e-07 30.3 0.0 1.7 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.10 RLN96048.1 - 0.0016 18.4 0.0 0.003 17.5 0.0 1.5 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 RLN96048.1 - 0.0032 17.2 0.0 0.007 16.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.6 RLN96048.1 - 0.0092 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MipZ PF09140.11 RLN96048.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 ATPase MipZ adh_short PF00106.25 RLN96049.1 - 3.6e-07 29.8 0.1 1.5e-06 27.8 0.0 2.0 2 1 1 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN96049.1 - 0.00093 18.8 0.0 0.0017 17.9 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.8 RLN96049.1 - 0.0067 16.2 0.2 0.013 15.3 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.10 RLN96049.1 - 0.0073 16.2 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 KR domain hSac2 PF12456.8 RLN96050.1 - 0.043 13.5 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Inositol phosphatase adh_short PF00106.25 RLN96051.1 - 8.8e-06 25.3 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.8 RLN96051.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.6 RLN96051.1 - 0.029 13.9 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN96051.1 - 0.053 13.4 0.0 0.08 12.9 0.0 1.2 1 0 0 1 1 1 0 KR domain Arm PF00514.23 RLN96052.1 - 3.5e-05 23.7 34.4 0.035 14.2 0.1 10.9 12 1 0 12 12 12 3 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 RLN96052.1 - 0.002 18.1 20.6 0.0096 15.9 0.0 7.9 9 1 0 9 9 9 2 Spinocerebellar ataxia type 10 protein domain WW PF00397.26 RLN96052.1 - 0.016 15.3 0.2 0.044 13.9 0.2 1.8 1 0 0 1 1 1 0 WW domain GTP_EFTU PF00009.27 RLN96053.1 - 6.6e-53 179.2 0.0 8.7e-53 178.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 RLN96053.1 - 8.8e-42 141.9 0.0 1.7e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 RLN96053.1 - 9e-13 48.4 0.1 2.2e-12 47.2 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RLN96053.1 - 0.0001 22.4 0.0 0.021 14.9 0.0 2.5 2 1 0 2 2 2 2 50S ribosome-binding GTPase FlpD PF02662.16 RLN96053.1 - 0.0022 18.0 0.0 0.02 14.9 0.0 2.2 2 0 0 2 2 2 1 Methyl-viologen-reducing hydrogenase, delta subunit GTP_EFTU_D4 PF14578.6 RLN96053.1 - 0.13 12.2 0.9 0.32 10.9 0.1 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Glyco_hydro_3_C PF01915.22 RLN96054.1 - 5e-46 157.2 0.0 7.7e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 RLN96054.1 - 3.7e-35 121.8 0.0 1.5e-34 119.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 RLN96054.1 - 1.5e-06 28.3 0.3 4.2e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain DAO PF01266.24 RLN96055.1 - 1.7e-52 179.2 0.0 2.3e-52 178.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 RLN96055.1 - 4e-35 120.4 0.0 7.1e-35 119.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 RLN96055.1 - 8.4e-10 38.3 3.5 2.7e-05 23.4 1.2 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 RLN96055.1 - 0.00032 20.0 0.1 0.0034 16.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 RLN96055.1 - 0.00081 18.6 1.7 0.11 11.5 0.9 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 RLN96055.1 - 0.003 17.0 2.7 0.003 17.0 2.7 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 RLN96055.1 - 0.012 14.3 0.6 0.025 13.3 0.6 1.5 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 RLN96055.1 - 0.025 13.9 0.1 1.3 8.2 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 RLN96055.1 - 0.026 13.8 2.3 0.34 10.1 0.3 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RLN96055.1 - 0.077 13.2 0.4 0.077 13.2 0.4 2.6 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 RLN96055.1 - 0.1 12.8 0.0 1.8 8.8 0.0 2.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 RLN96055.1 - 0.12 13.0 1.6 0.68 10.5 0.3 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 RLN96055.1 - 2.6 7.2 4.9 1.2 8.4 0.1 2.7 3 0 0 3 3 3 0 Thi4 family DDE_Tnp_1_7 PF13843.6 RLN96056.1 - 3.3e-21 76.0 0.0 3.9e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 PhaC_N PF07167.13 RLN96056.1 - 0.061 13.0 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus DDE_Tnp_1_7 PF13843.6 RLN96058.1 - 2.4e-14 53.4 0.1 3.7e-14 52.8 0.1 1.3 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 RLN96058.1 - 0.072 13.9 2.0 0.21 12.4 1.9 1.8 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon PUB PF09409.10 RLN96059.1 - 9.3e-19 67.2 0.0 2e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 PUB domain UBX PF00789.20 RLN96059.1 - 6.8e-05 23.0 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 UBX domain DUF5476 PF17570.2 RLN96059.1 - 1 9.8 3.4 4.4 7.8 3.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5476) SET PF00856.28 RLN96060.1 - 8.9e-18 65.2 0.1 8.9e-18 65.2 0.1 3.1 3 2 0 3 3 3 1 SET domain PHD PF00628.29 RLN96060.1 - 4e-13 49.0 42.0 1.4e-09 37.7 2.9 4.2 5 0 0 5 5 5 3 PHD-finger PHD_2 PF13831.6 RLN96060.1 - 0.00026 20.5 1.0 0.00026 20.5 1.0 3.8 4 0 0 4 4 4 1 PHD-finger AWS PF17907.1 RLN96060.1 - 0.0013 18.7 7.6 0.0065 16.5 1.2 3.4 2 0 0 2 2 2 1 AWS domain zf-HC5HC2H PF13771.6 RLN96060.1 - 0.16 12.3 33.3 0.024 14.9 7.2 4.3 3 1 1 4 4 4 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 RLN96060.1 - 4.6 7.4 32.4 0.034 14.3 5.8 4.0 2 1 2 4 4 4 0 PHD-zinc-finger like domain DUF4337 PF14235.6 RLN96060.1 - 5.4 7.1 8.6 10 6.2 2.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) TUG-UBL1 PF11470.8 RLN96061.1 - 3.4e-16 59.2 0.0 6.4e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 TUG ubiquitin-like domain UBX PF00789.20 RLN96061.1 - 0.038 14.2 0.1 0.09 13.0 0.0 1.6 2 0 0 2 2 2 0 UBX domain Phage_CI_C PF16452.5 RLN96062.1 - 0.0035 17.6 0.3 13 6.1 0.0 3.7 1 1 2 3 3 3 3 Bacteriophage CI repressor C-terminal domain 7TMR-DISM_7TM PF07695.11 RLN96063.1 - 0.007 16.3 2.2 0.0091 15.9 2.2 1.1 1 0 0 1 1 1 1 7TM diverse intracellular signalling NAD_binding_6 PF08030.12 RLN96063.1 - 0.0093 16.1 0.0 0.01 16.0 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Claudin_3 PF06653.11 RLN96063.1 - 0.043 13.8 0.6 0.061 13.3 0.6 1.1 1 0 0 1 1 1 0 Tight junction protein, Claudin-like EXS PF03124.14 RLN96063.1 - 0.053 12.8 0.2 0.07 12.4 0.2 1.1 1 0 0 1 1 1 0 EXS family Ferric_reduct PF01794.19 RLN96065.1 - 2.9e-19 69.4 10.6 2.9e-19 69.4 10.6 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 RLN96065.1 - 1.4e-18 66.9 0.0 2.9e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 RLN96065.1 - 1.4e-11 44.7 0.0 6.2e-11 42.7 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 RLN96065.1 - 0.092 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain HALZ PF02183.18 RLN96066.1 - 0.77 10.0 10.6 5.3 7.4 1.6 3.6 2 1 1 3 3 3 0 Homeobox associated leucine zipper Striatin PF08232.12 RLN96066.1 - 2 9.0 29.3 0.42 11.2 12.2 3.2 1 1 2 3 3 3 0 Striatin family TMF_TATA_bd PF12325.8 RLN96066.1 - 4.9 7.4 30.6 2.5 8.4 11.8 3.2 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding zf_C2H2_ZHX PF18387.1 RLN96067.1 - 2 8.1 5.4 0.88 9.3 2.2 1.9 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain TPR_1 PF00515.28 RLN96068.1 - 1.3e-19 69.1 2.0 1.6e-09 37.2 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN96068.1 - 2.9e-15 55.0 7.3 1.4e-07 31.1 0.0 3.5 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN96068.1 - 2.7e-11 42.7 7.3 3.5e-05 23.7 0.0 3.5 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN96068.1 - 1.1e-09 37.8 3.5 4.4e-06 26.3 0.1 2.9 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.6 RLN96068.1 - 5.8e-09 35.7 1.6 0.00041 20.5 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN96068.1 - 2.2e-08 34.2 3.7 0.00092 19.8 0.0 3.5 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN96068.1 - 1.1e-05 25.1 1.2 0.56 10.2 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN96068.1 - 5e-05 23.4 0.1 0.34 11.1 0.6 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat NARP1 PF12569.8 RLN96068.1 - 0.00026 20.0 0.7 0.028 13.3 0.4 2.0 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_12 PF13424.6 RLN96068.1 - 0.00036 20.8 6.9 0.037 14.3 0.1 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN96068.1 - 0.00052 20.6 8.0 0.0051 17.4 0.1 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN96068.1 - 0.002 18.0 0.8 0.037 14.0 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 RLN96068.1 - 0.016 14.5 1.9 1.4 8.1 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN96068.1 - 0.025 15.1 5.1 0.2 12.2 0.1 2.5 1 1 2 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN96068.1 - 0.035 14.3 1.9 0.13 12.5 1.5 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 RLN96068.1 - 0.096 11.7 0.1 0.095 11.7 0.1 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.17 RLN96068.1 - 0.15 12.5 2.4 19 5.7 0.0 2.4 1 1 1 2 2 2 0 Bacterial transcriptional activator domain MIT PF04212.18 RLN96068.1 - 0.19 11.8 0.0 0.19 11.8 0.0 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain NRBF2_MIT PF17169.4 RLN96068.1 - 0.26 11.5 2.7 0.79 10.0 0.1 2.2 1 1 1 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 TPR_6 PF13174.6 RLN96068.1 - 1.8 9.4 0.0 1.8 9.4 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN96069.1 - 1.6e-06 27.7 7.0 0.016 15.3 0.0 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN96069.1 - 4e-06 27.2 12.1 1.3 10.0 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat LRR_6 PF13516.6 RLN96069.1 - 2.3e-05 24.1 10.7 0.029 14.4 0.1 4.7 4 0 0 4 4 4 2 Leucine Rich repeat ANAPC3 PF12895.7 RLN96069.1 - 7.1e-05 23.0 2.2 0.4 10.9 0.1 3.8 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 RLN96069.1 - 0.00018 21.1 0.3 0.79 9.5 0.0 2.8 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 RLN96069.1 - 0.0024 17.9 0.6 0.16 12.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN96069.1 - 0.0026 18.2 6.5 4.6 7.8 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN96069.1 - 0.039 13.8 3.4 2.9 7.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN96069.1 - 0.092 13.4 1.7 26 5.7 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN96069.1 - 0.35 11.6 6.5 19 6.0 0.3 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat LRR_4 PF12799.7 RLN96069.1 - 1.5 9.4 8.8 2.9 8.4 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN96069.1 - 9.7 6.0 9.9 15 5.4 5.5 3.4 2 1 0 2 2 2 0 Leucine rich repeat PAS PF00989.25 RLN96070.1 - 1.3e-85 282.9 0.8 3.4e-19 68.9 0.0 5.3 5 0 0 5 5 5 5 PAS fold PAS_4 PF08448.10 RLN96070.1 - 2e-50 169.7 0.0 2.6e-11 43.7 0.0 5.9 6 0 0 6 6 6 5 PAS fold PAS_9 PF13426.7 RLN96070.1 - 1.9e-47 159.8 6.3 1.7e-11 44.2 0.1 5.8 6 0 0 6 6 6 5 PAS domain PAS_3 PF08447.12 RLN96070.1 - 1.1e-27 96.2 0.0 1.1e-06 28.9 0.0 5.4 5 0 0 5 5 5 5 PAS fold HATPase_c PF02518.26 RLN96070.1 - 8.6e-27 93.9 0.0 3e-26 92.1 0.0 2.0 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 RLN96070.1 - 4e-21 75.3 0.0 9.9e-21 74.0 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 RLN96070.1 - 6e-17 61.4 0.4 2.8e-16 59.3 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 RLN96070.1 - 3.5e-15 55.6 0.2 0.02 14.9 0.0 4.5 4 0 0 4 4 4 4 PAS domain Hpt PF01627.23 RLN96070.1 - 1.4e-06 28.5 0.3 3.9e-06 27.0 0.3 1.8 1 0 0 1 1 1 1 Hpt domain PAS_10 PF13596.6 RLN96070.1 - 1.8e-06 28.5 0.6 0.056 14.0 0.0 4.1 5 0 0 5 5 5 1 PAS domain PAS_7 PF12860.7 RLN96070.1 - 2.9e-05 24.2 3.0 0.26 11.5 0.2 5.6 5 3 0 5 5 5 1 PAS fold Pkinase PF00069.25 RLN96071.1 - 9.9e-41 139.8 0.0 7.9e-35 120.5 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN96071.1 - 1.2e-21 77.2 0.0 7.7e-20 71.3 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 RLN96071.1 - 0.066 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 RLN96071.1 - 0.073 11.8 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Arm PF00514.23 RLN96072.1 - 9.1e-192 616.2 224.8 2.8e-09 36.7 0.2 64.7 70 0 0 70 70 67 40 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 RLN96072.1 - 1.4e-39 136.1 4.9 0.0018 17.8 0.0 17.8 5 3 11 18 18 18 11 Armadillo-like HEAT_2 PF13646.6 RLN96072.1 - 5.9e-34 116.3 177.6 0.0058 17.0 1.5 33.5 15 8 21 39 39 37 17 HEAT repeats V-ATPase_H_N PF03224.14 RLN96072.1 - 4.8e-15 55.7 6.9 0.051 12.8 0.0 12.3 7 4 3 11 11 11 5 V-ATPase subunit H KAP PF05804.12 RLN96072.1 - 3e-12 45.6 0.0 0.0088 14.2 0.0 8.3 8 2 1 9 9 9 3 Kinesin-associated protein (KAP) V-ATPase_H_C PF11698.8 RLN96072.1 - 2.3e-08 34.2 4.2 2.3 8.3 0.0 10.9 11 1 1 12 12 11 1 V-ATPase subunit H Ank_2 PF12796.7 RLN96072.1 - 2.1e-07 31.4 0.7 4.5e-05 24.0 0.0 4.8 4 1 1 5 5 3 2 Ankyrin repeats (3 copies) Atx10homo_assoc PF09759.9 RLN96072.1 - 4.5e-06 26.6 20.5 21 5.2 0.0 14.4 16 2 1 18 18 15 0 Spinocerebellar ataxia type 10 protein domain Ank_4 PF13637.6 RLN96072.1 - 5e-05 23.8 1.5 0.033 14.8 0.1 4.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) RICTOR_V PF14668.6 RLN96072.1 - 0.00013 22.2 0.3 8.2 6.7 0.0 6.9 7 0 0 7 7 6 1 Rapamycin-insensitive companion of mTOR, domain 5 Ank_3 PF13606.6 RLN96072.1 - 0.0005 20.3 0.2 5.3 7.9 0.0 4.8 3 0 0 3 3 2 1 Ankyrin repeat Ank_5 PF13857.6 RLN96072.1 - 0.00068 19.9 1.6 4.2 7.8 0.0 5.1 5 0 0 5 5 4 1 Ankyrin repeats (many copies) DGF-1_C PF11040.8 RLN96072.1 - 0.012 15.6 0.3 7 6.7 0.0 4.0 3 0 0 3 3 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus HEAT_EZ PF13513.6 RLN96072.1 - 0.012 16.1 0.2 0.012 16.1 0.2 33.0 31 7 12 43 43 38 0 HEAT-like repeat UNC45-central PF11701.8 RLN96072.1 - 0.019 14.9 0.1 0.019 14.9 0.1 8.5 8 1 1 9 9 9 0 Myosin-binding striated muscle assembly central Ank PF00023.30 RLN96072.1 - 0.038 14.5 9.7 19 5.9 0.0 6.3 6 0 0 6 6 4 0 Ankyrin repeat HEAT PF02985.22 RLN96072.1 - 0.061 13.6 0.1 0.061 13.6 0.1 33.6 42 0 0 42 42 38 0 HEAT repeat Nipped-B_C PF12830.7 RLN96072.1 - 0.076 13.0 0.1 5.8 6.8 0.0 4.1 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus RICTOR_N PF14664.6 RLN96072.1 - 0.087 11.8 26.3 0.89 8.5 0.1 9.8 6 3 4 12 12 12 0 Rapamycin-insensitive companion of mTOR, N-term Dickkopf_N PF04706.12 RLN96072.1 - 0.94 10.0 2.7 61 4.2 0.0 4.1 4 0 0 4 4 4 0 Dickkopf N-terminal cysteine-rich region CLASP_N PF12348.8 RLN96072.1 - 3.4 7.2 11.3 58 3.1 0.1 6.4 7 0 0 7 7 7 0 CLASP N terminal Ribosomal_L7Ae PF01248.26 RLN96073.1 - 3.4e-26 90.8 0.0 4.7e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 RLN96073.1 - 4.6e-05 23.2 0.0 6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 RLN96073.1 - 0.004 17.2 0.0 0.0043 17.1 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 FHA PF00498.26 RLN96076.1 - 1.3e-15 57.5 0.0 2e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RLN96076.1 - 3.6e-05 24.0 0.1 0.0034 17.7 0.1 2.3 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DNA_pol_A_exo1 PF01612.20 RLN96077.1 - 3e-22 79.2 0.1 4.6e-11 42.7 0.1 2.4 2 0 0 2 2 2 2 3'-5' exonuclease TPR_1 PF00515.28 RLN96078.1 - 6.8e-30 101.6 27.7 0.00014 21.6 0.3 12.5 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_2 PF07719.17 RLN96078.1 - 2.6e-29 98.9 27.7 0.0008 19.3 0.0 12.2 12 1 0 12 12 12 6 Tetratricopeptide repeat TPR_11 PF13414.6 RLN96078.1 - 3.8e-27 93.7 6.7 0.00012 21.7 0.0 9.8 8 2 2 10 10 10 6 TPR repeat TPR_17 PF13431.6 RLN96078.1 - 4.7e-21 73.6 4.3 0.00093 19.4 0.0 8.0 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 RLN96078.1 - 3.3e-19 67.4 25.2 0.052 13.8 0.3 11.5 12 1 0 12 12 12 5 Tetratricopeptide repeat TPR_7 PF13176.6 RLN96078.1 - 7.8e-19 66.3 9.0 0.00093 19.1 0.0 8.9 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 RLN96078.1 - 1.1e-17 63.2 15.0 0.0025 18.5 0.0 10.6 8 4 5 13 13 11 4 Tetratricopeptide repeat TPR_16 PF13432.6 RLN96078.1 - 5.3e-15 55.8 6.4 0.018 15.6 0.0 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 RLN96078.1 - 4.5e-14 52.5 17.7 0.18 12.1 0.0 7.5 4 3 3 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 RLN96078.1 - 1.8e-13 50.8 15.1 0.0038 17.7 0.0 6.6 6 1 0 6 6 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 RLN96078.1 - 2.5e-09 37.2 5.9 0.00019 21.5 0.0 6.3 4 2 3 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN96078.1 - 1.9e-06 27.6 21.0 0.21 11.5 0.0 9.1 10 0 0 10 10 9 2 Tetratricopeptide repeat TAtT PF16811.5 RLN96078.1 - 0.0024 17.2 1.8 0.0046 16.3 0.6 2.1 2 0 0 2 2 2 1 TRAP transporter T-component Ada3 PF10198.9 RLN96078.1 - 0.0084 16.3 1.8 0.025 14.7 0.1 2.5 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 TPR_20 PF14561.6 RLN96078.1 - 0.009 16.3 3.8 9.9 6.6 0.1 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 RLN96078.1 - 0.01 15.8 1.5 29 4.8 0.2 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN96078.1 - 0.018 15.3 12.8 0.26 11.5 0.9 4.6 4 2 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.12 RLN96078.1 - 0.061 14.0 0.5 3.5 8.5 0.1 3.8 3 0 0 3 3 2 0 Sel1 repeat Siah-Interact_N PF09032.11 RLN96078.1 - 0.11 12.8 0.1 0.11 12.8 0.1 2.0 2 0 0 2 2 1 0 Siah interacting protein, N terminal TPR_4 PF07721.14 RLN96078.1 - 0.17 12.6 5.3 33 5.5 0.0 5.6 7 0 0 7 7 3 0 Tetratricopeptide repeat MIT PF04212.18 RLN96078.1 - 0.2 11.8 13.0 0.62 10.2 0.8 5.8 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 RLN96078.1 - 2.1 8.4 5.9 17 5.4 0.1 3.8 4 1 0 4 4 4 0 Domain of Unknown Function (DUF3856) ParcG PF10274.9 RLN96079.1 - 1.8e-39 135.8 0.0 2.1e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein Octopine_DH PF02317.17 RLN96080.1 - 2.3e-38 131.7 0.0 3.2e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain IlvN PF07991.12 RLN96080.1 - 0.0019 17.8 0.4 0.0074 15.9 0.4 1.8 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 RLN96080.1 - 0.0065 16.1 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 RLN96080.1 - 0.0092 16.5 0.1 0.018 15.6 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent YjeF_N PF03853.15 RLN96080.1 - 0.036 14.0 0.3 0.058 13.3 0.3 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus NAD_Gly3P_dh_N PF01210.23 RLN96080.1 - 0.056 13.4 0.2 0.1 12.6 0.2 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.6 RLN96080.1 - 0.12 11.7 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PDH PF02153.17 RLN96080.1 - 0.18 10.8 0.0 0.31 10.0 0.0 1.4 1 0 0 1 1 1 0 Prephenate dehydrogenase Biotin_lipoyl PF00364.22 RLN96081.1 - 1.8e-15 56.5 3.9 2.4e-15 56.1 3.9 1.2 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.19 RLN96081.1 - 0.00033 20.5 2.3 0.00058 19.7 2.3 1.4 1 1 0 1 1 1 1 Glycine cleavage H-protein S36_mt PF10937.8 RLN96081.1 - 0.017 16.7 5.3 0.23 13.0 0.3 2.9 2 1 1 3 3 3 0 Ribosomal protein S36, mitochondrial dCache_3 PF14827.6 RLN96081.1 - 0.11 12.2 1.1 0.15 11.7 1.1 1.3 1 1 0 1 1 1 0 Double sensory domain of two-component sensor kinase HlyD_3 PF13437.6 RLN96081.1 - 0.22 12.2 3.0 1.2 9.9 0.1 2.4 1 1 1 2 2 2 0 HlyD family secretion protein Ribosomal_60s PF00428.19 RLN96081.1 - 8.4 7.1 8.4 1.1e+02 3.5 8.4 2.3 1 1 0 1 1 1 0 60s Acidic ribosomal protein Not1 PF04054.15 RLN96082.1 - 2.7e-132 441.2 0.0 1.3e-131 438.9 0.0 1.9 1 1 0 1 1 1 1 CCR4-Not complex component, Not1 Med20 PF08612.11 RLN96082.1 - 1.2e-10 41.1 0.0 2.1e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex TPR_14 PF13428.6 RLN96083.1 - 1.4e-05 25.5 46.4 0.032 15.0 3.8 9.4 5 2 4 9 9 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 RLN96083.1 - 4.7e-05 23.8 35.0 0.021 15.4 0.3 7.1 4 2 3 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 RLN96083.1 - 8.8e-05 22.4 13.1 0.72 10.2 0.1 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN96083.1 - 0.0003 20.7 25.4 0.43 10.8 0.8 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN96083.1 - 0.00094 19.4 39.7 0.0057 16.9 0.3 7.1 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 RLN96083.1 - 0.0024 18.1 9.2 0.012 15.9 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN96083.1 - 0.0033 17.1 12.8 0.014 15.0 0.0 6.0 6 0 0 6 6 6 1 TPR repeat TPR_1 PF00515.28 RLN96083.1 - 0.0039 17.0 14.1 5.6 7.0 0.2 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN96083.1 - 1.6 9.6 8.7 13 6.6 0.0 4.9 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN96083.1 - 4.1 7.7 12.2 0.63 10.3 1.5 4.1 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2505 PF10698.9 RLN96083.1 - 5 7.2 6.6 3.1 7.9 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2505) Transket_pyr PF02779.24 RLN96084.1 - 7.6e-61 204.9 0.0 1.2e-60 204.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 RLN96084.1 - 2.5e-48 164.6 0.0 3.7e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 RLN96084.1 - 2.1e-43 147.6 0.0 5.2e-43 146.4 0.0 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal GDPD PF03009.17 RLN96085.1 - 2.2e-46 158.7 0.0 3.3e-46 158.1 0.0 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Dockerin_1 PF00404.18 RLN96085.1 - 0.033 14.4 0.1 0.079 13.2 0.1 1.6 1 0 0 1 1 1 0 Dockerin type I domain EF-hand_5 PF13202.6 RLN96085.1 - 0.09 12.3 2.0 1.3 8.6 0.4 2.6 2 0 0 2 2 2 0 EF hand FGGY_N PF00370.21 RLN96086.1 - 2e-12 47.2 0.0 3.7e-12 46.3 0.0 1.4 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DRMBL PF07522.14 RLN96087.1 - 1.4e-27 96.1 0.0 3.8e-27 94.6 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 RLN96087.1 - 0.00024 20.7 0.1 0.00053 19.5 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 RLN96087.1 - 0.018 15.0 0.2 0.032 14.2 0.2 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily BIR PF00653.21 RLN96087.1 - 0.022 15.4 1.2 1.9 9.2 0.0 3.5 2 1 1 3 3 3 0 Inhibitor of Apoptosis domain zf-CpG_bind_C PF12269.8 RLN96087.1 - 0.033 14.0 5.1 0.94 9.2 0.1 3.3 3 1 1 4 4 4 0 CpG binding protein zinc finger C terminal domain zf-Mss51 PF13824.6 RLN96087.1 - 0.18 12.0 0.7 22 5.2 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 RNHCP PF12647.7 RLN96087.1 - 0.52 10.3 4.9 20 5.2 0.3 3.6 3 1 1 4 4 4 0 RNHCP domain zf-C2H2 PF00096.26 RLN96087.1 - 6.9 7.3 6.1 71 4.1 0.2 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type AAA_26 PF13500.6 RLN96088.1 - 1.6e-37 129.2 0.0 2.2e-36 125.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 RLN96088.1 - 0.00029 20.9 0.6 0.0032 17.5 0.7 2.5 1 1 1 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain DRTGG PF07085.12 RLN96088.1 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 DRTGG domain ER_lumen_recept PF00810.18 RLN96089.1 - 5.4e-51 173.3 5.8 5.4e-51 173.3 5.8 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 RLN96089.1 - 0.052 13.3 8.5 0.064 13.0 0.1 4.1 2 2 3 5 5 5 0 PQ loop repeat IPK PF03770.16 RLN96090.1 - 1.6e-49 168.4 0.0 3.1e-49 167.5 0.0 1.5 2 0 0 2 2 2 1 Inositol polyphosphate kinase MCPVI PF02993.14 RLN96090.1 - 0.13 12.0 1.2 0.25 11.2 1.2 1.4 1 0 0 1 1 1 0 Minor capsid protein VI Ion_trans PF00520.31 RLN96091.1 - 1.8e-66 223.8 29.2 1.6e-46 158.5 14.6 2.1 2 0 0 2 2 2 2 Ion transport protein GPHH PF16905.5 RLN96091.1 - 3e-10 39.7 0.0 7.7e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 RLN96091.1 - 3.8e-10 39.0 17.8 3.9e-07 29.1 1.0 3.3 2 1 1 3 3 3 3 Polycystin cation channel Sedlin_N PF04628.13 RLN96093.1 - 1.1e-14 54.7 0.0 2.6e-07 30.8 0.0 2.2 1 1 1 2 2 2 2 Sedlin, N-terminal conserved region Sybindin PF04099.12 RLN96093.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.6 2 0 0 2 2 2 0 Sybindin-like family Dimer_Tnp_hAT PF05699.14 RLN96094.1 - 3.6e-08 33.1 0.0 1.3e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 RLN96094.1 - 3.3e-07 30.2 1.7 3.6e-07 30.1 0.3 1.8 2 0 0 2 2 2 1 BED zinc finger Pheromone PF08015.11 RLN96094.1 - 0.39 11.8 7.5 8.5 7.5 3.1 4.2 3 1 0 3 3 3 0 Fungal mating-type pheromone eRF1_1 PF03463.15 RLN96095.1 - 3.3e-37 127.4 0.0 1.1e-36 125.7 0.0 1.9 1 1 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 RLN96095.1 - 2.1e-29 102.5 0.1 4.7e-29 101.4 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 2 NAD_binding_2 PF03446.15 RLN96095.1 - 5.3e-27 94.9 0.6 1.1e-26 93.9 0.6 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase eRF1_3 PF03465.15 RLN96095.1 - 2.2e-23 82.9 0.0 6.5e-23 81.4 0.0 1.9 1 0 0 1 1 1 1 eRF1 domain 3 NAD_binding_11 PF14833.6 RLN96095.1 - 4.2e-18 65.8 0.1 1.1e-17 64.4 0.1 1.7 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 RLN96095.1 - 0.00036 21.1 0.0 0.00094 19.7 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 RLN96095.1 - 0.00074 18.9 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 RLN96095.1 - 0.0019 18.1 0.1 0.0039 17.1 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 RLN96095.1 - 0.01 15.4 0.0 0.032 13.8 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 RLN96095.1 - 0.036 13.7 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA HTH_57 PF18679.1 RLN96095.1 - 0.051 13.9 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 ThcOx helix turn helix domain TrkA_N PF02254.18 RLN96095.1 - 0.055 13.7 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 TrkA-N domain Med21 PF11221.8 RLN96097.1 - 0.058 13.7 0.6 2.5 8.3 0.3 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Fumble PF03630.14 RLN96098.1 - 1.7e-90 303.6 3.0 1.9e-78 263.9 1.2 2.1 1 1 1 2 2 2 2 Fumble Palm_thioest PF02089.15 RLN96099.1 - 1.2e-44 153.0 0.1 1.6e-44 152.6 0.1 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 RLN96099.1 - 0.0027 17.3 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 RLN96099.1 - 0.0068 16.1 0.0 0.011 15.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 RLN96099.1 - 0.023 14.3 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Enamelin PF15362.6 RLN96099.1 - 0.22 9.8 1.6 0.34 9.2 1.6 1.2 1 0 0 1 1 1 0 Enamelin PA_decarbox PF05870.11 RLN96100.1 - 1.1e-08 34.8 0.3 2.3e-08 33.8 0.2 1.5 1 1 0 1 1 1 1 Phenolic acid decarboxylase (PAD) MoaF PF10703.9 RLN96100.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 MoaF N-terminal domain Sugar_tr PF00083.24 RLN96101.1 - 8.9e-84 281.9 22.9 1.2e-83 281.5 22.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN96101.1 - 6.5e-24 84.5 47.6 3.9e-22 78.6 29.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Eno-Rase_NADH_b PF12242.8 RLN96101.1 - 0.17 11.7 0.2 0.4 10.5 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase LCM PF04072.14 RLN96102.1 - 9.6e-36 123.5 0.0 1.2e-35 123.2 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase PhoLip_ATPase_C PF16212.5 RLN96103.1 - 1e-30 107.3 10.4 1.7e-30 106.6 10.4 1.3 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 RLN96103.1 - 6.7e-14 51.7 0.0 4.2e-13 49.2 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RLN96103.1 - 0.024 14.9 0.4 2.6 8.3 0.0 2.6 2 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase Gloverin PF10793.9 RLN96103.1 - 0.039 13.8 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 Gloverin-like protein DDE_1 PF03184.19 RLN96104.1 - 8.1e-10 38.6 0.0 1.5e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN96104.1 - 2e-08 34.2 0.1 4.2e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HSF_DNA-bind PF00447.17 RLN96105.1 - 4.4e-22 78.5 3.0 7.1e-22 77.8 3.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Fibrillarin PF01269.17 RLN96106.1 - 2.3e-27 95.6 0.0 2.9e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin Mur_ligase_M PF08245.12 RLN96108.1 - 4e-05 23.7 0.0 0.00032 20.8 0.0 2.4 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 RLN96108.1 - 9.9e-05 22.5 0.0 0.00029 21.0 0.0 1.8 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain PAN_4 PF14295.6 RLN96109.1 - 7.3e-06 25.8 4.8 1.5e-05 24.8 4.8 1.6 1 0 0 1 1 1 1 PAN domain CAP PF00188.26 RLN96109.1 - 0.00088 20.1 0.0 0.0016 19.3 0.0 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DLH PF01738.18 RLN96110.1 - 1.4e-17 64.0 0.4 1.7e-17 63.7 0.4 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF357 PF04010.13 RLN96110.1 - 0.027 14.5 0.3 0.067 13.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF357) GTP_EFTU PF00009.27 RLN96111.1 - 1.2e-52 178.3 0.0 2e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 RLN96111.1 - 9.7e-41 138.6 0.1 1.9e-40 137.7 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 RLN96111.1 - 2.6e-12 47.0 0.7 8.3e-12 45.3 0.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RLN96111.1 - 0.00018 21.6 0.0 0.037 14.1 0.0 2.5 2 1 0 2 2 2 2 50S ribosome-binding GTPase FlpD PF02662.16 RLN96111.1 - 0.024 14.7 0.0 0.29 11.1 0.0 2.2 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit GTP_EFTU_D4 PF14578.6 RLN96111.1 - 0.049 13.5 0.1 0.18 11.7 0.1 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 SURF2 PF05477.11 RLN96113.1 - 1.3e-16 61.0 5.8 7.1e-16 58.6 0.0 2.4 3 0 0 3 3 3 2 Surfeit locus protein 2 (SURF2) DUF4551 PF15087.6 RLN96113.1 - 3.4 6.4 16.1 0.13 11.1 10.4 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) GFO_IDH_MocA PF01408.22 RLN96114.1 - 5.6e-24 85.3 0.1 7.2e-24 84.9 0.1 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Rossmann-like PF10727.9 RLN96114.1 - 1.2e-05 25.2 0.2 1.5e-05 24.8 0.2 1.3 1 0 0 1 1 1 1 Rossmann-like domain F420_oxidored PF03807.17 RLN96114.1 - 0.0012 19.3 0.0 0.0021 18.6 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.16 RLN96114.1 - 0.0042 17.7 0.0 0.0057 17.3 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 RLN96114.1 - 0.0093 16.4 0.0 0.016 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 RLN96114.1 - 0.016 14.6 0.5 0.027 13.8 0.5 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 RLN96114.1 - 0.022 15.0 0.5 0.57 10.4 0.1 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 RLN96114.1 - 0.037 14.3 0.1 0.092 13.0 0.1 1.6 1 1 0 1 1 1 0 TrkA-N domain Semialdhyde_dh PF01118.24 RLN96114.1 - 0.087 13.3 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Arm PF00514.23 RLN96115.1 - 2.3e-18 65.5 47.8 0.009 16.0 0.0 17.2 17 1 0 18 18 18 6 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 RLN96115.1 - 0.0037 16.8 5.2 0.81 9.1 0.1 3.6 3 0 0 3 3 3 2 Armadillo-like V-ATPase_H_N PF03224.14 RLN96115.1 - 0.18 11.1 9.8 0.29 10.4 0.0 4.7 5 2 0 5 5 5 0 V-ATPase subunit H KAP PF05804.12 RLN96115.1 - 0.22 9.6 4.9 0.23 9.5 0.3 3.2 3 1 0 3 3 3 0 Kinesin-associated protein (KAP) DUF913 PF06025.12 RLN96115.1 - 0.36 9.7 10.2 0.34 9.8 0.0 4.3 4 2 1 5 5 5 0 Domain of Unknown Function (DUF913) Vac14_Fab1_bd PF12755.7 RLN96115.1 - 0.44 11.2 4.6 12 6.6 0.0 4.6 4 1 1 5 5 5 0 Vacuolar 14 Fab1-binding region ABC_tran PF00005.27 RLN96116.1 - 4.4e-31 108.2 0.1 7.2e-31 107.5 0.1 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 RLN96116.1 - 5.7e-20 71.7 35.0 2.1e-18 66.6 22.6 3.7 3 1 1 4 4 4 2 ABC-2 family transporter protein AAA_21 PF13304.6 RLN96116.1 - 1.8e-07 31.3 0.1 6.5e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RLN96116.1 - 0.0022 17.5 0.1 0.2 11.1 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 RLN96116.1 - 0.058 13.6 0.0 0.46 10.7 0.0 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 RLN96116.1 - 0.24 11.9 0.0 0.38 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Bromodomain PF00439.25 RLN96118.1 - 2.4e-08 33.9 0.0 5.1e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Bromodomain DNMT1-RFD PF12047.8 RLN96118.1 - 1.8e-06 28.0 0.1 1.8e-06 28.0 0.1 2.4 3 0 0 3 3 3 1 Cytosine specific DNA methyltransferase replication foci domain DDT PF02791.17 RLN96118.1 - 0.00072 19.8 0.1 0.0012 19.1 0.1 1.3 1 0 0 1 1 1 1 DDT domain Lung_7-TM_R PF06814.13 RLN96121.1 - 3.6e-38 131.5 13.7 4.2e-38 131.3 11.4 2.1 3 0 0 3 3 3 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 RLN96121.1 - 5.3e-05 22.8 3.1 0.00011 21.7 3.1 1.5 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain VSP PF03302.13 RLN96122.1 - 0.044 12.7 0.1 0.062 12.2 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Amnionless PF14828.6 RLN96122.1 - 0.06 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 RLN96122.1 - 0.21 12.5 1.3 0.36 11.8 0.1 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Oxidored_FMN PF00724.20 RLN96123.1 - 1.6e-78 264.4 0.0 2.5e-78 263.7 0.0 1.3 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RCC1 PF00415.18 RLN96125.1 - 3.4e-71 235.7 19.8 1.6e-14 54.2 0.1 8.5 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN96125.1 - 1.2e-43 146.1 26.8 4.9e-10 38.9 0.2 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RabGAP-TBC PF00566.18 RLN96125.1 - 1.5e-40 139.1 0.0 2.9e-40 138.2 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PX PF00787.24 RLN96125.1 - 1.6e-06 28.1 0.0 3.9e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 PX domain Hira PF07569.11 RLN96125.1 - 0.034 13.9 0.0 66 3.1 0.0 3.7 3 0 0 3 3 3 0 TUP1-like enhancer of split TFIIA PF03153.13 RLN96125.1 - 0.89 9.5 14.8 1.5 8.7 14.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cnd3 PF12719.7 RLN96126.1 - 7.7e-41 140.2 3.4 1.2e-40 139.6 1.9 2.1 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 RLN96126.1 - 5e-06 26.8 13.2 0.0071 16.7 0.6 4.4 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 RLN96126.1 - 0.0012 18.9 13.0 0.56 10.6 0.0 7.0 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 RLN96126.1 - 0.018 15.5 2.8 12 6.5 0.0 5.0 3 1 2 5 5 5 0 HEAT-like repeat Hepar_II_III PF07940.13 RLN96126.1 - 0.062 12.9 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Heparinase II/III-like protein Voldacs PF03517.13 RLN96126.1 - 1.5 8.9 16.1 20 5.3 0.0 2.9 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling U-box PF04564.15 RLN96128.1 - 4.2e-26 90.9 0.0 8.9e-26 89.9 0.0 1.6 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 RLN96128.1 - 9.8e-08 31.5 6.4 0.00093 18.9 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN96128.1 - 1.1e-06 28.2 2.7 0.14 12.3 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-NOSIP PF15906.5 RLN96128.1 - 9.8e-05 22.4 0.1 0.00039 20.5 0.0 2.1 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein TPR_11 PF13414.6 RLN96128.1 - 0.0019 17.8 4.2 0.19 11.5 0.0 3.4 4 0 0 4 4 4 2 TPR repeat zf-RING_UBOX PF13445.6 RLN96128.1 - 0.0087 16.1 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger TPR_8 PF13181.6 RLN96128.1 - 0.012 15.7 0.8 1.6 9.2 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN96128.1 - 0.023 15.3 3.4 1 10.1 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN96128.1 - 0.041 14.7 1.7 4.3 8.4 0.2 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN96128.1 - 0.055 14.0 1.2 0.47 11.0 0.5 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN96128.1 - 0.099 13.3 0.5 6.8 7.6 0.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_28 PF13521.6 RLN96131.1 - 0.00024 21.4 0.1 0.00068 19.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RLN96131.1 - 0.00036 21.1 0.8 0.0017 18.9 0.1 2.5 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RLN96131.1 - 0.00036 19.9 0.0 0.0008 18.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 RLN96131.1 - 0.00085 19.5 0.2 0.006 16.8 0.2 2.3 1 1 1 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 RLN96131.1 - 0.0014 18.5 0.2 0.08 12.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA PF00004.29 RLN96131.1 - 0.0021 18.5 0.4 0.26 11.7 0.2 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 RLN96131.1 - 0.0076 16.2 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_5 PF07728.14 RLN96131.1 - 0.013 15.4 0.2 0.048 13.7 0.1 2.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) CbiA PF01656.23 RLN96131.1 - 0.033 14.2 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 RLN96131.1 - 0.036 13.6 2.3 0.14 11.8 2.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RLN96131.1 - 0.041 13.6 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 RLN96131.1 - 0.064 13.0 0.0 0.31 10.7 0.0 2.0 3 0 0 3 3 3 0 Sigma-54 interaction domain HEPN_AbiV PF18728.1 RLN96131.1 - 0.13 12.4 2.9 9.4 6.4 0.9 2.3 2 0 0 2 2 2 0 AbiV NTPase_1 PF03266.15 RLN96131.1 - 0.15 12.0 1.5 15 5.5 0.1 2.3 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.27 RLN96131.1 - 0.16 12.5 1.4 0.34 11.4 1.2 1.9 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 RLN96131.1 - 0.2 12.0 0.0 0.6 10.5 0.0 1.9 1 1 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 RLN96131.1 - 0.6 10.5 9.5 5.5 7.3 9.5 2.4 1 1 0 1 1 1 0 AAA ATPase domain CENP-B_dimeris PF09026.10 RLN96131.1 - 0.99 9.8 12.6 4.5 7.7 11.2 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sox_N PF12444.8 RLN96131.1 - 2.3 9.4 11.4 22 6.3 0.1 3.6 3 0 0 3 3 3 0 Sox developmental protein N terminal AMP-binding PF00501.28 RLN96132.1 - 1.1e-10 40.7 0.0 1.2e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Cellulase PF00150.18 RLN96133.1 - 3e-24 86.0 5.7 4.4e-24 85.4 5.7 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 RLN96133.1 - 0.07 12.4 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Beta-galactosidase Pacifastin_I PF05375.13 RLN96133.1 - 0.16 11.7 3.0 0.29 10.9 3.0 1.4 1 0 0 1 1 1 0 Pacifastin inhibitor (LCMII) Glyco_hydro_17 PF00332.18 RLN96134.1 - 1e-12 48.3 0.3 1.6e-05 24.7 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.13 RLN96134.1 - 0.0015 17.6 0.4 0.0031 16.6 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 RIFIN PF02009.16 RLN96134.1 - 8.2 6.2 8.1 24 4.7 8.1 1.8 1 0 0 1 1 1 0 Rifin EphA2_TM PF14575.6 RLN96135.1 - 0.012 16.5 0.0 0.025 15.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CcmD PF04995.14 RLN96135.1 - 0.23 11.5 2.8 0.5 10.5 2.8 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF4381 PF14316.6 RLN96135.1 - 0.28 11.4 0.4 0.61 10.3 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) SKG6 PF08693.10 RLN96135.1 - 2 7.9 6.8 3.8 7.0 6.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Glyco_hydro_17 PF00332.18 RLN96136.1 - 1.6e-14 54.3 0.3 1.2e-11 44.8 0.3 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_17 PF00332.18 RLN96137.1 - 5.1e-19 69.0 0.4 2.2e-11 43.9 0.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 DUF211 PF02680.14 RLN96137.1 - 4.7 7.4 5.6 2.4 8.4 1.0 2.7 3 0 0 3 3 3 0 Uncharacterized ArCR, COG1888 Sugar_tr PF00083.24 RLN96138.1 - 0.0001 21.3 0.2 0.00012 21.1 0.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter ERCC3_RAD25_C PF16203.5 RLN96139.1 - 3.9e-85 285.0 0.1 4.7e-85 284.7 0.1 1.0 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C PF00271.31 RLN96139.1 - 9.6e-11 42.0 0.0 1.6e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RNR_N PF08343.10 RLN96139.1 - 0.075 13.1 0.2 0.23 11.5 0.1 1.8 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal Coa1 PF08695.10 RLN96141.1 - 0.00011 21.9 0.0 0.0014 18.4 0.0 2.6 3 0 0 3 3 3 1 Cytochrome oxidase complex assembly protein 1 Cep57_MT_bd PF06657.13 RLN96142.1 - 0.039 14.4 14.3 0.19 12.2 5.1 2.8 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 MHC_II_beta PF00969.19 RLN96142.1 - 0.049 13.8 0.3 0.049 13.8 0.3 1.7 2 0 0 2 2 1 0 Class II histocompatibility antigen, beta domain Fez1 PF06818.15 RLN96142.1 - 0.05 14.1 17.1 0.063 13.7 17.1 1.2 1 0 0 1 1 1 0 Fez1 Filament PF00038.21 RLN96142.1 - 0.065 12.8 19.2 0.13 11.8 19.0 1.5 1 1 0 1 1 1 0 Intermediate filament protein AAA_13 PF13166.6 RLN96142.1 - 0.12 11.0 10.2 0.14 10.7 10.2 1.0 1 0 0 1 1 1 0 AAA domain FapA PF03961.13 RLN96142.1 - 0.21 10.1 10.6 0.26 9.9 10.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Jnk-SapK_ap_N PF09744.9 RLN96142.1 - 0.23 11.7 23.2 2 8.6 7.6 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 ELM2 PF01448.24 RLN96142.1 - 0.37 11.6 2.9 32 5.4 0.0 2.6 2 0 0 2 2 2 0 ELM2 domain GAS PF13851.6 RLN96142.1 - 0.43 9.9 22.1 1.3 8.3 9.1 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HSCB_C PF07743.13 RLN96142.1 - 0.45 11.1 15.3 3.1 8.4 3.5 2.3 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain MADF_DNA_bdg PF10545.9 RLN96142.1 - 0.5 10.7 10.8 1 9.7 4.3 2.1 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4337 PF14235.6 RLN96142.1 - 0.51 10.4 14.9 1.3 9.1 14.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) DUF573 PF04504.14 RLN96142.1 - 0.53 11.0 4.5 0.73 10.5 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF573 Wtap PF17098.5 RLN96142.1 - 0.63 10.0 16.5 0.09 12.7 8.3 2.2 1 1 1 2 2 2 0 WTAP/Mum2p family SHE3 PF17078.5 RLN96142.1 - 0.68 9.6 14.2 0.58 9.8 6.1 2.0 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 KxDL PF10241.9 RLN96142.1 - 0.71 10.2 11.3 0.43 10.9 4.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF1664 PF07889.12 RLN96142.1 - 0.85 9.7 7.2 3.6 7.6 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 RLN96142.1 - 0.98 10.1 14.6 3.4 8.4 1.3 2.9 1 1 1 2 2 2 0 Initiation control protein YabA Ribosomal_L29 PF00831.23 RLN96142.1 - 1 9.4 14.4 2 8.4 0.4 3.1 1 1 2 3 3 3 0 Ribosomal L29 protein SOGA PF11365.8 RLN96142.1 - 1 10.5 14.4 1.1 10.5 12.2 2.1 1 1 1 2 2 2 0 Protein SOGA DUF4407 PF14362.6 RLN96142.1 - 1.2 8.5 13.4 1.4 8.2 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Uso1_p115_C PF04871.13 RLN96142.1 - 1.5 9.2 19.2 0.38 11.1 13.6 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region EspB_PE PF18625.1 RLN96142.1 - 1.6 9.2 11.2 6.6 7.3 2.3 3.0 1 1 1 2 2 2 0 ESX-1 secreted protein B PE domain Prominin PF05478.11 RLN96142.1 - 1.8 6.4 6.6 2 6.3 6.6 1.0 1 0 0 1 1 1 0 Prominin Asp-B-Hydro_N PF05279.11 RLN96142.1 - 1.9 8.5 11.1 2.2 8.3 11.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AAA_11 PF13086.6 RLN96142.1 - 2 8.2 12.9 2.3 7.9 12.9 1.1 1 0 0 1 1 1 0 AAA domain PIEZO PF15917.5 RLN96142.1 - 2 7.9 12.4 2.9 7.3 12.3 1.4 1 1 0 1 1 1 0 Piezo SpecificRecomb PF10136.9 RLN96142.1 - 2.1 6.5 8.9 2.5 6.3 8.9 1.1 1 0 0 1 1 1 0 Site-specific recombinase DUF2203 PF09969.9 RLN96142.1 - 2.1 9.1 11.0 3.3 8.4 10.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) TSC22 PF01166.18 RLN96142.1 - 2.2 8.6 11.9 1.9 8.9 0.4 3.0 2 1 1 3 3 3 0 TSC-22/dip/bun family Atg14 PF10186.9 RLN96142.1 - 2.6 7.0 17.2 3 6.8 17.2 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CorA PF01544.18 RLN96142.1 - 3.4 6.9 12.5 3.9 6.7 12.5 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein V_ATPase_I PF01496.19 RLN96142.1 - 3.7 5.4 9.3 4.1 5.2 9.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-O PF09496.10 RLN96142.1 - 3.8 7.4 10.5 12 5.8 10.5 1.8 1 1 0 1 1 1 0 Cenp-O kinetochore centromere component Katanin_con80 PF13925.6 RLN96142.1 - 6.9 6.7 11.3 0.73 9.9 2.7 2.0 1 1 1 2 2 2 0 con80 domain of Katanin Enkurin PF13864.6 RLN96142.1 - 7.1 7.1 18.4 1.4 9.4 11.5 2.2 1 1 1 2 2 2 0 Calmodulin-binding ArAE_2_N PF10337.9 RLN96142.1 - 8.9 5.2 6.5 10 5.0 6.5 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Dpy-30 PF05186.13 RLN96143.1 - 2.6e-13 49.4 0.1 5e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.22 RLN96143.1 - 8e-07 29.3 0.0 0.15 12.1 0.0 3.3 3 0 0 3 3 3 2 Adenylate kinase AAA_17 PF13207.6 RLN96143.1 - 0.00048 20.6 0.7 0.11 12.9 0.0 3.5 3 1 0 4 4 4 1 AAA domain Hydin_ADK PF17213.3 RLN96143.1 - 0.0005 20.4 2.6 0.012 16.0 0.0 3.3 2 1 1 3 3 3 1 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 RLN96143.1 - 0.038 14.2 14.7 0.073 13.2 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.6 RLN96143.1 - 0.14 12.7 0.0 1.7 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RLN96143.1 - 0.31 11.3 0.0 0.31 11.3 0.0 3.0 3 2 0 3 3 3 0 AAA domain ParcG PF10274.9 RLN96144.1 - 4.3e-53 180.1 0.0 5.4e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein Kinesin PF00225.23 RLN96145.1 - 1.4e-90 303.6 0.0 3.3e-90 302.4 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN96145.1 - 9.7e-16 58.0 0.0 7.9e-15 55.1 0.0 2.2 1 1 0 1 1 1 1 Microtubule binding YabA PF06156.13 RLN96145.1 - 1.2 9.8 13.3 3.6 8.3 0.0 4.1 3 1 0 3 3 3 0 Initiation control protein YabA Shugoshin_N PF07558.11 RLN96145.1 - 2 8.3 4.6 22 5.0 0.1 2.6 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Ank_2 PF12796.7 RLN96148.1 - 2.9e-74 245.7 53.5 1.1e-09 38.7 0.0 13.0 2 2 13 17 17 17 17 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN96148.1 - 7.4e-62 204.6 64.2 1.5e-05 25.1 0.1 26.9 7 4 20 27 27 27 20 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN96148.1 - 8.3e-60 198.5 48.5 1e-07 32.4 0.1 19.1 11 6 9 21 21 21 15 Ankyrin repeats (many copies) ATG101 PF07855.12 RLN96148.1 - 1.9e-31 109.1 0.0 4.4e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 Autophagy-related protein 101 Ank_3 PF13606.6 RLN96148.1 - 1.1e-30 102.2 25.7 1.7 9.5 0.0 24.0 26 1 1 27 27 27 5 Ankyrin repeat DUF5049 PF16468.5 RLN96148.1 - 1.1e-08 34.9 0.0 79 3.3 0.0 11.2 7 3 5 13 13 13 0 Domain of unknown function (DUF5049) Ank PF00023.30 RLN96148.1 - 7e-06 26.3 9.9 3e+02 2.1 0.0 14.1 9 6 5 14 14 14 0 Ankyrin repeat Daxx PF03344.15 RLN96148.1 - 0.0016 18.5 0.1 12 6.1 0.0 5.9 5 2 0 5 5 5 1 Daxx N-terminal Rassf1C-interacting domain DUF3425 PF11905.8 RLN96148.1 - 0.025 14.6 0.2 0.37 10.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3425) DUF1987 PF09345.10 RLN96148.1 - 4.1 7.1 8.4 43 3.8 0.0 6.7 9 0 0 9 9 9 0 Domain of unknown function (DUF1987) Ank_5 PF13857.6 RLN96149.1 - 7.5e-32 109.0 23.0 0.00029 21.1 0.2 13.6 4 2 10 14 14 14 11 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN96149.1 - 1.1e-31 109.2 9.0 4e-07 30.5 0.1 6.3 1 1 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN96149.1 - 1.1e-27 96.0 17.3 1.2e-05 25.8 0.1 9.9 8 4 1 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN96149.1 - 9.2e-19 65.6 5.1 12 6.9 0.0 12.8 9 2 3 12 12 12 3 Ankyrin repeat DUF5049 PF16468.5 RLN96149.1 - 0.00043 20.1 0.1 56 3.7 0.0 5.8 7 1 1 8 8 8 0 Domain of unknown function (DUF5049) Ank PF00023.30 RLN96149.1 - 0.0064 16.9 2.2 80 3.9 0.0 7.2 5 4 3 8 8 8 0 Ankyrin repeat Daxx PF03344.15 RLN96149.1 - 0.044 13.8 0.0 12 6.0 0.0 3.8 3 1 1 4 4 4 0 Daxx N-terminal Rassf1C-interacting domain DUF249 PF03158.13 RLN96149.1 - 1.6 8.4 5.5 29 4.3 0.0 4.7 3 3 2 5 5 5 0 Multigene family 530 protein TPR_1 PF00515.28 RLN96150.1 - 2.6e-15 55.5 8.5 0.0015 18.2 0.0 4.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 RLN96150.1 - 3.3e-12 45.5 14.8 0.0022 18.0 0.1 4.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 RLN96150.1 - 2.5e-08 34.1 5.2 0.00056 20.2 2.3 3.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN96150.1 - 1.3e-07 32.1 2.7 1.3e-07 32.1 2.7 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN96150.1 - 2e-07 30.5 4.7 0.49 10.5 0.2 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN96150.1 - 1.9e-06 27.6 4.4 0.041 14.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN96150.1 - 3.7e-06 27.2 7.8 0.018 15.6 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN96150.1 - 7.2e-06 26.4 4.4 9.5e-06 26.0 1.3 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN96150.1 - 8.6e-06 25.9 1.0 8.6e-06 25.9 1.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 RLN96150.1 - 4.8e-05 23.8 1.9 0.00014 22.4 1.9 1.7 1 0 0 1 1 1 1 Bacterial transcriptional activator domain TPR_17 PF13431.6 RLN96150.1 - 9.2e-05 22.6 0.5 0.87 10.1 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN96150.1 - 0.00029 21.4 13.3 0.011 16.5 1.1 4.9 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN96150.1 - 0.00053 19.6 7.3 0.0028 17.3 0.2 3.6 3 1 1 4 4 4 1 TPR repeat TPR_9 PF13371.6 RLN96150.1 - 0.016 15.3 1.5 0.63 10.2 0.5 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat Ank_4 PF13637.6 RLN96151.1 - 1.1e-15 57.7 0.7 3.6e-12 46.5 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN96151.1 - 1.2e-15 57.8 0.8 9.8e-09 35.7 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 RLN96151.1 - 1.2e-12 47.7 7.4 3e-05 24.2 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 RLN96151.1 - 6.9e-10 38.3 0.8 0.00021 21.4 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 RLN96151.1 - 1.6e-07 31.4 3.9 7.3e-05 23.0 0.1 3.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) RepB-RCR_reg PF10723.9 RLN96151.1 - 0.081 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Replication regulatory protein RepB HTH_Tnp_Tc5 PF03221.16 RLN96152.1 - 1.5e-05 25.0 0.1 4.3e-05 23.5 0.1 1.9 1 1 0 1 1 1 1 Tc5 transposase DNA-binding domain Rad50_zn_hook PF04423.14 RLN96153.1 - 2.1e-05 24.3 1.0 2.1e-05 24.3 1.0 4.0 2 0 0 2 2 2 1 Rad50 zinc hook motif SbcCD_C PF13558.6 RLN96153.1 - 0.00043 20.5 0.0 0.0015 18.7 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit CALCOCO1 PF07888.11 RLN96153.1 - 0.0033 16.4 42.7 0.0033 16.4 42.7 5.6 2 1 2 5 5 5 1 Calcium binding and coiled-coil domain (CALCOCO1) like CPG4 PF15481.6 RLN96153.1 - 0.11 13.1 2.3 6.4 7.5 0.3 3.8 3 0 0 3 3 3 0 Chondroitin proteoglycan 4 adh_short PF00106.25 RLN96153.1 - 0.49 9.8 9.6 0.022 14.2 1.2 2.7 2 0 0 2 2 2 0 short chain dehydrogenase Ribosomal_60s PF00428.19 RLN96154.1 - 1.4e-20 73.7 3.5 1.7e-20 73.4 3.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 RLN96154.1 - 0.0048 17.2 0.0 0.0075 16.6 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain Ras PF00071.22 RLN96155.1 - 4e-22 78.6 0.1 1.4e-16 60.5 0.1 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 RLN96155.1 - 1.1e-18 67.6 0.1 5.9e-18 65.2 0.1 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN96155.1 - 2e-05 24.1 0.1 0.00014 21.3 0.2 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RLN96155.1 - 0.024 14.0 0.1 0.035 13.5 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TruD PF01142.18 RLN96157.1 - 1.6e-58 198.5 0.0 4.8e-55 187.0 0.0 3.5 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Styelin PF17562.2 RLN96157.1 - 0.027 14.8 0.2 0.069 13.5 0.2 1.7 1 0 0 1 1 1 0 Styelin APG17 PF04108.12 RLN96157.1 - 0.037 13.1 0.3 0.062 12.4 0.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 TruD PF01142.18 RLN96158.1 - 5.3e-74 249.5 0.0 3e-70 237.2 0.0 3.3 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) DNA_pol_alpha_N PF12254.8 RLN96158.1 - 0.079 13.1 0.2 0.31 11.2 0.2 2.0 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Acetyltransf_11 PF13720.6 RLN96158.1 - 0.88 10.1 2.6 5.7 7.5 0.0 3.5 5 0 0 5 5 5 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 ECH_1 PF00378.20 RLN96159.1 - 7.2e-16 58.2 0.3 2e-13 50.2 0.1 2.5 1 1 2 3 3 3 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RLN96159.1 - 4.7e-08 32.9 0.8 0.00056 19.5 0.1 3.0 1 1 2 3 3 3 3 Enoyl-CoA hydratase/isomerase Pkinase PF00069.25 RLN96160.1 - 1.1e-57 195.5 0.0 3e-57 194.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain PH_3 PF14593.6 RLN96160.1 - 3.7e-33 113.7 0.1 3.7e-33 113.7 0.1 1.6 2 0 0 2 2 2 1 PH domain Pkinase_Tyr PF07714.17 RLN96160.1 - 8.6e-27 94.0 1.5 1.2e-22 80.5 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RLN96160.1 - 6e-05 22.5 0.0 8.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RLN96160.1 - 0.00046 19.1 0.0 0.0007 18.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN96160.1 - 0.0017 18.3 0.0 0.0037 17.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN96160.1 - 0.0053 16.1 0.0 0.0087 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L22e PF01776.17 RLN96161.1 - 2.1e-45 153.6 0.2 2.6e-45 153.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family ADP_PFK_GK PF04587.15 RLN96161.1 - 0.019 13.6 0.0 0.02 13.5 0.0 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region tRNA-synt_2d PF01409.20 RLN96162.1 - 1e-30 107.0 0.1 1.4e-30 106.5 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 RLN96162.1 - 4.4e-19 68.5 0.1 8.9e-19 67.5 0.1 1.5 1 0 0 1 1 1 1 PheRS DNA binding domain 3 PheRS_DBD1 PF18552.1 RLN96162.1 - 2e-09 37.0 0.2 6.4e-09 35.4 0.0 1.9 2 0 0 2 2 2 1 PheRS DNA binding domain 1 GerPE PF10970.8 RLN96162.1 - 0.092 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Spore germination protein GerPE Pkinase PF00069.25 RLN96163.1 - 1.9e-46 158.6 0.0 2.8e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN96163.1 - 4.8e-44 150.6 0.0 7.3e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN96163.1 - 0.013 15.4 0.0 0.18 11.7 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN96163.1 - 0.02 13.9 0.0 0.23 10.4 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain TMEM154 PF15102.6 RLN96163.1 - 0.022 14.7 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Kdo PF06293.14 RLN96163.1 - 0.03 13.7 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN96163.1 - 0.036 12.9 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase CBM_5_12 PF02839.14 RLN96163.1 - 0.47 11.1 2.9 2 9.2 2.9 2.1 1 0 0 1 1 1 0 Carbohydrate binding domain Pkinase PF00069.25 RLN96164.1 - 1.2e-50 172.4 0.0 2.7e-50 171.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN96164.1 - 6.5e-48 163.3 0.0 8.1e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN96164.1 - 0.0031 16.4 0.0 0.0054 15.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN96164.1 - 0.0083 16.1 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1593 PF07632.11 RLN96164.1 - 0.023 14.2 0.1 0.038 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) MAP17 PF15807.5 RLN96164.1 - 0.023 14.9 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Haspin_kinase PF12330.8 RLN96164.1 - 0.026 13.5 0.0 0.082 11.8 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain TMEM154 PF15102.6 RLN96164.1 - 0.055 13.4 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family FAM176 PF14851.6 RLN96164.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 FAM176 family EphA2_TM PF14575.6 RLN96164.1 - 0.13 13.1 0.1 0.32 11.9 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain HSP70 PF00012.20 RLN96165.1 - 2.6e-36 125.0 0.0 3.3e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN96165.1 - 1.3e-07 30.8 0.0 1.7e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 MreB/Mbl protein HSP70 PF00012.20 RLN96167.1 - 2.6e-36 125.0 0.0 3.3e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN96167.1 - 1.3e-07 30.8 0.0 1.7e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 MreB/Mbl protein Sigma70_ner PF04546.13 RLN96168.1 - 0.052 13.4 0.3 0.077 12.9 0.3 1.5 1 1 0 1 1 1 0 Sigma-70, non-essential region Hydantoinase_A PF01968.18 RLN96169.1 - 1.2 8.3 3.4 2.1 7.5 2.0 2.1 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase CBFD_NFYB_HMF PF00808.23 RLN96169.1 - 6.2 7.2 6.8 21 5.5 3.4 2.8 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Glyco_hydro_30 PF02055.16 RLN96173.1 - 5.7e-25 88.0 0.2 7.3e-25 87.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 RLN96173.1 - 1.4e-17 63.6 0.3 1.9e-17 63.2 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain SpoIIAA-like PF11964.8 RLN96173.1 - 0.12 13.4 0.0 0.15 13.1 0.0 1.2 1 0 0 1 1 1 0 SpoIIAA-like Chromate_transp PF02417.15 RLN96174.1 - 6.1e-48 162.9 36.6 5.1e-38 130.7 17.3 3.5 2 1 0 2 2 2 2 Chromate transporter Phage_holin_3_1 PF05106.12 RLN96174.1 - 0.11 13.0 5.3 1.9 9.0 0.2 2.5 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) 7tm_7 PF08395.12 RLN96174.1 - 0.31 10.2 2.7 2 7.5 0.3 2.1 2 0 0 2 2 2 0 7tm Chemosensory receptor DUF4134 PF13572.6 RLN96174.1 - 0.93 9.8 6.0 11 6.4 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4134) ABC2_membrane PF01061.24 RLN96175.1 - 1.5e-35 122.6 36.4 1.8e-32 112.5 26.7 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN96175.1 - 4.7e-17 62.8 0.0 8.9e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN96175.1 - 4.8e-05 23.3 0.0 0.052 13.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN96175.1 - 0.0019 18.1 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 RLN96175.1 - 0.004 16.3 16.3 0.004 16.3 16.3 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 RLN96175.1 - 0.0044 16.7 0.7 0.0098 15.6 0.7 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN96175.1 - 0.012 16.0 0.7 0.055 13.8 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.19 RLN96175.1 - 0.022 14.2 0.0 0.051 13.0 0.0 1.5 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Bac_export_2 PF01312.19 RLN96175.1 - 0.029 13.6 3.2 0.052 12.7 3.2 1.4 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family AAA_23 PF13476.6 RLN96175.1 - 0.035 14.6 0.1 0.06 13.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain PDR_assoc PF08370.11 RLN96175.1 - 0.079 12.7 0.1 0.079 12.7 0.1 2.9 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Guanylate_cyc PF00211.20 RLN96176.1 - 2.2e-92 307.7 4.2 1.7e-52 177.7 0.4 3.4 3 0 0 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain PhoLip_ATPase_C PF16212.5 RLN96176.1 - 2.6e-65 220.6 20.3 2.6e-65 220.6 20.3 3.7 4 0 0 4 4 4 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RLN96176.1 - 2.5e-23 81.6 1.1 6e-23 80.3 1.1 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RLN96176.1 - 1.6e-09 38.4 0.1 0.00023 21.5 0.0 3.5 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN96176.1 - 2.9e-05 24.0 0.0 0.00017 21.6 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RLN96176.1 - 0.00052 19.6 0.0 0.0029 17.1 0.0 2.3 1 1 0 1 1 1 1 E1-E2 ATPase HNOBA PF07701.14 RLN96176.1 - 0.047 13.1 1.9 2.2 7.7 0.1 2.4 2 0 0 2 2 2 0 Heme NO binding associated Sensor_TM1 PF13755.6 RLN96176.1 - 0.075 12.8 0.5 0.24 11.2 0.5 1.8 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain Hydrolase_3 PF08282.12 RLN96176.1 - 0.19 11.5 0.1 0.47 10.2 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ank_2 PF12796.7 RLN96177.1 - 1.7e-08 34.9 0.3 3e-06 27.7 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN96177.1 - 6.4e-07 29.5 1.7 0.042 14.2 0.1 4.6 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN96177.1 - 2.6e-06 27.8 2.9 0.0013 19.3 0.1 4.0 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN96177.1 - 0.02 15.4 1.0 9.4 7.2 0.0 4.5 5 0 0 5 5 5 0 Ankyrin repeat DUF5049 PF16468.5 RLN96177.1 - 0.05 13.5 0.1 3.8 7.5 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5049) Transketolase_N PF00456.21 RLN96178.1 - 3.7e-126 420.6 0.1 1.9e-125 418.2 0.1 1.9 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 RLN96178.1 - 1e-39 136.1 0.1 1.7e-39 135.3 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 RLN96178.1 - 8.7e-09 35.3 0.0 2.4e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 RLN96178.1 - 0.00044 19.5 0.0 0.0007 18.9 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 RLN96178.1 - 0.0011 18.8 0.1 0.029 14.2 0.0 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Adenyl_transf PF04439.12 RLN96178.1 - 0.092 11.9 0.2 0.27 10.3 0.1 1.7 2 0 0 2 2 2 0 Streptomycin adenylyltransferase E1_dh PF00676.20 RLN96178.1 - 0.099 11.6 0.0 0.2 10.6 0.0 1.5 1 0 0 1 1 1 0 Dehydrogenase E1 component Mur_ligase_C PF02875.21 RLN96178.1 - 0.11 12.7 0.1 5 7.4 0.0 2.6 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain XFP_C PF09363.10 RLN96178.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 XFP C-terminal domain HTH_38 PF13936.6 RLN96179.1 - 3.6e-06 26.6 3.0 3.6e-06 26.6 3.0 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_32 PF13565.6 RLN96179.1 - 0.00038 21.0 8.0 0.0037 17.9 0.7 2.5 2 0 0 2 2 2 2 Homeodomain-like domain HTH_Tnp_Tc3_1 PF11427.8 RLN96179.1 - 0.0024 17.7 0.1 0.0055 16.5 0.1 1.6 1 0 0 1 1 1 1 Tc3 transposase HTH_23 PF13384.6 RLN96179.1 - 0.0044 16.8 5.9 0.0051 16.6 1.3 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_11 PF08279.12 RLN96179.1 - 0.71 9.9 4.1 2.7 8.0 0.4 2.4 2 0 0 2 2 2 0 HTH domain Aldo_ket_red PF00248.21 RLN96181.1 - 2.1e-69 234.0 0.0 2.4e-69 233.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AbbA_antirepres PF14156.6 RLN96183.1 - 0.056 13.3 0.4 1.7 8.6 0.0 2.2 2 0 0 2 2 2 0 Antirepressor AbbA B-block_TFIIIC PF04182.12 RLN96184.1 - 6.7e-10 39.0 0.0 4.5e-09 36.3 0.0 2.5 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC LRR_4 PF12799.7 RLN96185.1 - 3.6e-07 30.4 2.6 0.0073 16.7 0.2 2.6 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN96185.1 - 0.0061 16.3 3.1 0.028 14.2 0.8 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 RLN96185.1 - 0.0092 16.0 5.6 8.2 6.8 0.0 4.3 3 1 1 4 4 4 2 Leucine Rich repeat LRR_9 PF14580.6 RLN96185.1 - 0.096 12.2 0.9 0.39 10.2 0.9 2.2 1 1 0 1 1 1 0 Leucine-rich repeat HECT PF00632.25 RLN96186.1 - 9.3e-57 192.8 0.0 1.7e-56 191.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ank_2 PF12796.7 RLN96186.1 - 3.3e-10 40.4 0.0 1.2e-09 38.6 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN96186.1 - 1.9e-08 33.9 0.1 0.012 16.1 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 RLN96186.1 - 6.3e-07 29.6 0.9 0.0064 16.9 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 RLN96186.1 - 7.6e-06 26.1 0.1 0.0024 18.1 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN96186.1 - 9.2e-06 26.1 0.0 5.2e-05 23.7 0.0 2.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-RanBP PF00641.18 RLN96186.1 - 0.003 16.8 7.5 0.0041 16.4 1.2 2.6 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 RLN96186.1 - 0.01 15.8 6.9 0.041 13.9 1.5 3.1 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger DZR PF12773.7 RLN96186.1 - 0.021 14.9 1.6 0.051 13.6 1.6 1.6 1 0 0 1 1 1 0 Double zinc ribbon Vps36-NZF-N PF16988.5 RLN96186.1 - 0.98 8.9 4.0 15 5.0 1.4 3.0 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Ank_2 PF12796.7 RLN96187.1 - 4.5e-21 75.2 0.4 1.2e-09 38.6 0.0 4.0 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN96187.1 - 1.2e-17 64.0 0.8 3.7e-10 40.1 0.0 4.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN96187.1 - 7.1e-17 61.3 0.5 1.6e-08 34.6 0.0 4.7 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN96187.1 - 6.2e-15 54.9 0.1 0.0038 17.6 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 RLN96187.1 - 8.9e-13 47.2 0.1 0.019 15.5 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat AAA_9 PF12781.7 RLN96187.1 - 3.1e-05 23.2 0.0 0.00012 21.3 0.0 2.0 2 1 0 2 2 2 1 ATP-binding dynein motor region Rhabdo_M2 PF04785.12 RLN96187.1 - 0.18 11.1 0.1 0.28 10.5 0.1 1.3 1 0 0 1 1 1 0 Rhabdovirus matrix protein M2 Pkinase_Tyr PF07714.17 RLN96188.1 - 6.1e-36 124.0 0.0 4.7e-23 81.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN96188.1 - 1.2e-34 119.9 0.0 7.2e-34 117.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain DEP PF00610.21 RLN96188.1 - 0.00011 22.2 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PIP49_C PF12260.8 RLN96188.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 APH PF01636.23 RLN96188.1 - 0.018 15.0 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 RLN96189.1 - 2.7e-36 125.2 0.0 4.7e-23 81.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN96189.1 - 5e-36 124.4 0.0 2.9e-35 121.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain DEP PF00610.21 RLN96189.1 - 0.00011 22.2 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PIP49_C PF12260.8 RLN96189.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 APH PF01636.23 RLN96189.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.7 RLN96190.1 - 2.8e-34 117.5 4.2 2.8e-08 34.2 0.1 6.8 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN96190.1 - 5e-29 100.3 16.4 0.00018 22.0 0.1 10.5 6 3 4 10 10 10 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN96190.1 - 5.3e-29 99.9 18.6 0.0022 18.3 0.3 14.0 5 4 10 15 15 15 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN96190.1 - 7.6e-18 62.8 2.6 0.68 10.7 0.0 13.2 15 0 0 15 15 15 2 Ankyrin repeat DUF5049 PF16468.5 RLN96190.1 - 0.00012 21.9 0.0 65 3.5 0.0 6.8 4 2 4 8 8 8 0 Domain of unknown function (DUF5049) Ank PF00023.30 RLN96190.1 - 0.00036 20.8 0.5 26 5.5 0.0 7.1 6 4 1 7 7 7 0 Ankyrin repeat DUF249 PF03158.13 RLN96190.1 - 0.13 11.9 3.4 4.5 6.9 0.0 4.1 2 2 0 4 4 4 0 Multigene family 530 protein Chorion_S16 PF05836.12 RLN96190.1 - 1.4 9.2 6.1 5.5 7.3 0.1 4.0 3 1 2 5 5 5 0 Chorion protein S16 CNOT1_HEAT PF16418.5 RLN96190.1 - 1.5 8.9 2.9 24 4.9 0.0 4.1 4 1 1 5 5 5 0 CCR4-NOT transcription complex subunit 1 HEAT repeat LZ_Tnp_IS481 PF13011.6 RLN96190.1 - 3.8 8.1 5.2 54 4.4 0.2 4.0 2 2 2 4 4 4 0 leucine-zipper of insertion element IS481 Pkinase PF00069.25 RLN96191.1 - 4e-37 128.0 0.0 4.6e-26 91.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN96191.1 - 4.1e-37 127.9 0.0 3.2e-22 79.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase DEP PF00610.21 RLN96191.1 - 3e-05 24.0 0.0 6.8e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) APH PF01636.23 RLN96191.1 - 0.001 19.1 0.1 0.0053 16.7 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN96191.1 - 0.07 12.1 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 RLN96191.1 - 0.14 11.5 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 RLN96191.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 RLN96192.1 - 5.6e-39 134.1 0.0 1.2e-37 129.8 0.0 2.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN96192.1 - 1.2e-35 123.0 0.0 7.8e-23 81.1 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase DEP PF00610.21 RLN96192.1 - 0.00089 19.3 0.0 0.0024 17.9 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) APH PF01636.23 RLN96192.1 - 0.011 15.6 0.1 0.054 13.4 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family MgsA_C PF12002.8 RLN96193.1 - 5.3e-55 185.9 0.0 1.3e-54 184.7 0.0 1.6 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 RLN96193.1 - 3.9e-23 81.6 0.5 9.8e-23 80.3 0.3 1.8 2 0 0 2 2 2 1 AAA C-terminal domain RNF220 PF15926.5 RLN96193.1 - 0.00072 19.3 0.4 0.0023 17.6 0.1 1.9 2 0 0 2 2 2 1 E3 ubiquitin-protein ligase RNF220 AAA PF00004.29 RLN96193.1 - 0.011 16.2 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Nop10p PF04135.12 RLN96193.1 - 0.089 12.9 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family CRM1_C PF08767.11 RLN96194.1 - 8.1e-06 25.2 0.3 1.9e-05 24.0 0.3 1.6 1 0 0 1 1 1 1 CRM1 C terminal Pkinase PF00069.25 RLN96195.1 - 1.5e-36 126.1 0.0 4e-36 124.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN96195.1 - 2.5e-35 122.0 0.0 3.2e-23 82.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DEP PF00610.21 RLN96195.1 - 0.0024 17.9 0.0 0.005 16.9 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) B-block_TFIIIC PF04182.12 RLN96196.1 - 0.00026 21.1 0.0 0.00074 19.6 0.0 1.8 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC Hydrolase_4 PF12146.8 RLN96197.1 - 9.5e-10 38.1 0.2 5.4e-08 32.4 0.3 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 RLN96197.1 - 0.025 14.2 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) IMUP PF15761.5 RLN96197.1 - 0.11 13.3 2.2 0.21 12.3 2.2 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein Pkinase_Tyr PF07714.17 RLN96198.1 - 3e-26 92.3 0.0 4.4e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN96198.1 - 2.8e-17 62.9 0.0 4.4e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF202 PF02656.15 RLN96198.1 - 0.03 14.8 0.5 7.5 7.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Consortin_C PF15281.6 RLN96198.1 - 0.07 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Consortin C-terminus DUF4366 PF14283.6 RLN96198.1 - 0.15 12.1 0.1 0.23 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) EGF_2 PF07974.13 RLN96199.1 - 6.2e-16 58.5 64.0 9.5e-06 25.9 6.8 5.5 5 0 0 5 5 5 5 EGF-like domain Laminin_EGF PF00053.24 RLN96199.1 - 0.084 13.0 54.8 0.24 11.6 7.2 4.8 3 1 1 4 4 4 0 Laminin EGF domain EGF PF00008.27 RLN96199.1 - 3.4 8.1 45.9 0.79 10.1 2.3 5.7 5 0 0 5 5 5 0 EGF-like domain DUF423 PF04241.15 RLN96200.1 - 1.9e-24 85.6 1.0 1.9e-24 85.6 1.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF423) UAA PF08449.11 RLN96201.1 - 8.6e-58 195.9 10.7 1.1e-57 195.6 10.7 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 RLN96201.1 - 7.8e-12 45.5 16.7 8.2e-07 29.3 6.7 2.4 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 RLN96201.1 - 1.7e-06 27.4 6.1 0.0011 18.2 0.2 2.2 1 1 1 2 2 2 2 Nucleotide-sugar transporter CRT-like PF08627.10 RLN96201.1 - 3.3e-06 26.3 1.5 1.8e-05 23.8 0.1 2.1 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 RLN96201.1 - 6.5e-06 25.7 6.5 0.0033 16.8 1.0 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family Kinesin PF00225.23 RLN96202.1 - 5.4e-71 239.2 0.2 6.3e-70 235.7 0.2 2.5 1 1 0 1 1 1 1 Kinesin motor domain Mago-bind PF09282.10 RLN96202.1 - 0.0041 16.9 0.5 0.0041 16.9 0.5 2.2 2 0 0 2 2 2 1 Mago binding Microtub_bd PF16796.5 RLN96202.1 - 0.02 14.8 0.0 0.23 11.4 0.0 2.6 1 1 1 2 2 2 0 Microtubule binding Peptidase_S66 PF02016.15 RLN96202.1 - 1.5 8.9 3.9 1.4 9.1 0.1 3.1 3 0 0 3 3 3 0 LD-carboxypeptidase N-terminal domain Peptidase_M19 PF01244.21 RLN96202.1 - 5.2 6.1 8.1 0.6 9.2 0.5 3.2 3 1 2 5 5 5 0 Membrane dipeptidase (Peptidase family M19) RRM_1 PF00076.22 RLN96204.1 - 2.7e-17 62.3 0.0 5.3e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 RLN96204.1 - 2.8e-10 39.9 23.7 6e-06 26.0 5.4 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RLN96204.1 - 5.7e-10 38.9 29.6 0.00011 22.2 0.9 3.3 3 0 0 3 3 3 3 Zinc finger domain Torus PF16131.5 RLN96204.1 - 1.8e-08 35.1 20.2 0.00047 20.8 0.5 4.4 2 1 1 4 4 4 3 Torus domain zf-CCCH_4 PF18044.1 RLN96204.1 - 2.1e-05 24.2 27.3 0.0023 17.7 1.0 3.3 3 0 0 3 3 3 3 CCCH-type zinc finger zf-CCCH_3 PF15663.5 RLN96204.1 - 0.00028 21.1 9.4 0.27 11.4 6.3 3.1 2 1 0 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 RLN96204.1 - 0.009 16.5 19.5 1.2 9.7 1.2 3.4 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger RRM_7 PF16367.5 RLN96204.1 - 0.043 13.9 0.0 0.13 12.4 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif Acetyltransf_13 PF13880.6 RLN96205.1 - 7.2e-24 83.6 0.0 1.3e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 RLN96205.1 - 3.4e-15 55.6 0.2 5.9e-15 54.8 0.2 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.25 RLN96205.1 - 0.0021 18.3 0.0 0.004 17.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RLN96205.1 - 0.0024 18.3 0.0 0.012 16.0 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Arm PF00514.23 RLN96206.1 - 2.3e-56 186.2 13.1 6.2e-07 29.3 0.1 11.5 11 1 0 11 11 11 10 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 RLN96206.1 - 4.6e-10 39.4 0.1 0.17 11.9 0.0 5.4 4 1 1 5 5 5 3 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 RLN96206.1 - 1.8e-09 37.9 29.2 0.012 16.1 2.1 9.3 7 2 5 12 12 11 6 HEAT-like repeat HEAT_2 PF13646.6 RLN96206.1 - 1.6e-08 34.8 32.7 0.00072 19.9 1.1 6.8 1 1 7 8 8 8 6 HEAT repeats HEAT PF02985.22 RLN96206.1 - 1e-07 31.5 12.5 1.7 9.1 0.0 9.9 11 1 1 12 12 12 2 HEAT repeat Arm_2 PF04826.13 RLN96206.1 - 2.2e-07 30.6 0.0 0.0063 16.0 0.0 4.0 2 2 2 4 4 4 2 Armadillo-like V-ATPase_H_N PF03224.14 RLN96206.1 - 1.5e-05 24.5 0.0 0.26 10.5 0.0 3.7 1 1 1 2 2 2 2 V-ATPase subunit H UNC45-central PF11701.8 RLN96206.1 - 0.00014 21.8 0.5 2.7 7.9 0.2 4.8 3 3 2 5 5 5 1 Myosin-binding striated muscle assembly central HEAT_PBS PF03130.16 RLN96206.1 - 0.00032 21.1 38.0 0.66 10.8 0.1 11.7 13 0 0 13 13 13 2 PBS lyase HEAT-like repeat Acyl-CoA_dh_N PF02771.16 RLN96206.1 - 0.00099 19.7 2.2 21 5.8 0.0 6.4 7 2 1 8 8 8 0 Acyl-CoA dehydrogenase, N-terminal domain PUL PF08324.11 RLN96206.1 - 0.018 14.3 9.7 0.088 12.0 4.4 3.4 2 1 1 3 3 3 0 PUL domain Rsa3 PF14615.6 RLN96206.1 - 0.096 12.3 0.5 18 5.0 0.0 3.9 3 0 0 3 3 3 0 Ribosome-assembly protein 3 DUF3361 PF11841.8 RLN96206.1 - 0.11 12.5 0.3 39 4.1 0.0 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF3361) DUF5308 PF17233.2 RLN96206.1 - 1.1 9.5 11.1 17 5.6 0.1 4.3 2 2 0 3 3 3 0 Family of unknown function (DUF5308) BT1 PF03092.16 RLN96208.1 - 1.1e-10 40.4 1.3 1.1e-10 40.4 1.3 2.4 2 0 0 2 2 2 2 BT1 family PUCC PF03209.15 RLN96208.1 - 0.0016 17.5 14.8 0.042 12.8 14.8 2.3 1 1 0 1 1 1 1 PUCC protein HSF_DNA-bind PF00447.17 RLN96209.1 - 1.2e-20 73.9 3.8 2e-20 73.2 3.8 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding PriCT_1 PF08708.11 RLN96210.1 - 0.068 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) Biotin_carb_C PF02785.19 RLN96211.1 - 6.8e-33 113.0 0.0 1.9e-32 111.5 0.0 1.8 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain CPSase_L_D2 PF02786.17 RLN96211.1 - 5.5e-25 88.1 0.0 9.1e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_lipoyl PF00364.22 RLN96211.1 - 3.9e-18 65.1 0.4 9e-18 63.9 0.4 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 RLN96211.1 - 4.2e-05 23.3 0.1 0.028 14.2 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 RLN96211.1 - 0.0033 17.0 0.0 0.0066 16.0 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 RLN96211.1 - 0.013 16.2 0.0 6.8 7.5 0.0 3.5 3 0 0 3 3 3 0 HlyD family secretion protein DUF2110 PF09883.9 RLN96211.1 - 0.047 13.3 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) Myb_DNA-binding PF00249.31 RLN96212.1 - 6.6e-07 29.4 0.0 1.2e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain UreF PF01730.16 RLN96212.1 - 0.011 16.3 1.4 0.02 15.5 1.4 1.6 1 1 0 1 1 1 0 UreF MtN3_slv PF03083.16 RLN96213.1 - 8.6e-32 109.0 26.9 3.3e-12 46.3 5.0 3.4 4 0 0 4 4 4 3 Sugar efflux transporter for intercellular exchange BaxI_1 PF12811.7 RLN96213.1 - 1.9 8.0 13.3 0.027 14.0 1.5 2.8 2 2 0 2 2 2 0 Bax inhibitor 1 like Dimerisation2 PF16864.5 RLN96214.1 - 0.046 13.7 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Dimerisation domain ERM PF00769.19 RLN96214.1 - 0.13 12.0 27.1 0.039 13.8 20.6 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family SLC12 PF03522.15 RLN96214.1 - 0.16 11.0 4.6 0.18 10.8 4.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Rootletin PF15035.6 RLN96214.1 - 0.44 10.5 16.0 0.058 13.4 12.0 1.5 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Antigen_Bd37 PF11641.8 RLN96214.1 - 0.66 9.4 7.5 0.73 9.3 6.7 1.4 1 1 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein DUF16 PF01519.16 RLN96214.1 - 1.7 9.2 9.4 4.6 7.8 3.0 3.1 1 1 2 3 3 3 0 Protein of unknown function DUF16 LOH1CR12 PF10158.9 RLN96214.1 - 2.1 8.4 12.4 1.4 9.0 3.7 2.7 1 1 2 3 3 3 0 Tumour suppressor protein CENP-K PF11802.8 RLN96214.1 - 3.1 7.3 12.9 5.3 6.5 12.9 1.5 1 1 0 1 1 1 0 Centromere-associated protein K DUF1664 PF07889.12 RLN96214.1 - 6.1 6.9 9.9 1.4 8.9 2.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) 4HBT_2 PF13279.6 RLN96215.1 - 4.8e-07 30.3 0.1 6.4e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Pentapeptide PF00805.22 RLN96215.1 - 0.088 12.5 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) His_Phos_1 PF00300.22 RLN96216.1 - 1.6e-14 54.1 0.2 8.8e-13 48.4 0.2 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PH PF00169.29 RLN96216.1 - 1.4e-07 32.0 0.0 2.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN96216.1 - 0.0045 17.2 0.0 0.0081 16.4 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain NAD_binding_1 PF00175.21 RLN96217.1 - 4.3e-28 98.1 0.0 6.9e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 RLN96217.1 - 3.2e-26 91.5 0.0 5e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 RLN96217.1 - 0.0012 19.0 0.0 0.0058 16.8 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain EF-hand_1 PF00036.32 RLN96218.1 - 2.2e-82 264.6 21.1 3.5e-06 26.2 0.0 16.0 16 0 0 16 16 16 14 EF hand EF-hand_7 PF13499.6 RLN96218.1 - 2.5e-82 271.3 26.9 7.2e-11 42.4 0.5 8.7 8 0 0 8 8 8 8 EF-hand domain pair EF-hand_6 PF13405.6 RLN96218.1 - 4.2e-71 228.9 31.2 1.5e-06 27.7 0.2 15.9 16 0 0 16 16 16 14 EF-hand domain EF-hand_5 PF13202.6 RLN96218.1 - 1e-63 208.2 25.8 1.1e-05 24.7 0.1 14.6 14 0 0 14 14 14 14 EF hand EF-hand_8 PF13833.6 RLN96218.1 - 6.6e-53 176.4 37.0 1.6e-08 34.3 0.3 13.1 9 4 4 13 13 13 12 EF-hand domain pair EF-hand_9 PF14658.6 RLN96218.1 - 8.5e-12 45.2 3.3 1.5 9.2 0.0 7.9 8 0 0 8 8 8 4 EF-hand domain SPARC_Ca_bdg PF10591.9 RLN96218.1 - 8.6e-12 45.4 2.4 0.47 10.8 0.0 8.3 7 2 0 7 7 7 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 RLN96218.1 - 3.4e-09 36.8 9.6 0.92 9.4 0.1 8.5 8 1 1 9 9 9 2 Caleosin related protein EF-hand_4 PF12763.7 RLN96218.1 - 0.00052 19.9 10.7 16 5.5 0.0 8.2 4 2 5 9 9 9 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 RLN96218.1 - 0.0055 16.9 1.8 3 8.1 0.0 5.4 7 1 0 7 7 7 1 Dockerin type I domain EF-hand_14 PF17959.1 RLN96218.1 - 0.27 11.6 7.5 84 3.6 0.0 5.8 6 0 0 6 6 6 0 EF-hand domain MscS_porin PF12795.7 RLN96219.1 - 0.01 15.4 11.8 0.041 13.4 11.8 2.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Collagen PF01391.18 RLN96219.1 - 0.081 12.7 11.4 0.029 14.1 4.6 2.4 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Csm1_N PF18504.1 RLN96219.1 - 0.13 12.7 0.6 0.64 10.4 0.1 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain GAS PF13851.6 RLN96219.1 - 0.31 10.4 4.6 0.58 9.5 4.0 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.6 RLN96219.1 - 2.2 8.4 6.8 1.5 8.9 0.8 3.1 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 FUSC PF04632.12 RLN96219.1 - 2.7 6.4 18.0 6.2 5.2 18.0 1.6 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fez1 PF06818.15 RLN96219.1 - 3.7 7.9 9.6 7.7 6.9 9.6 1.6 1 0 0 1 1 1 0 Fez1 PHA_gran_rgn PF09650.10 RLN96220.1 - 0.48 10.7 2.4 3.5 8.0 0.1 2.7 2 0 0 2 2 2 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) AAA_13 PF13166.6 RLN96220.1 - 4.7 5.7 6.1 2.8 6.5 0.4 2.0 2 0 0 2 2 2 0 AAA domain DinI PF06183.13 RLN96221.1 - 0.063 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 DinI-like family MULE PF10551.9 RLN96222.1 - 0.002 18.5 1.1 0.0047 17.3 0.1 2.1 2 1 1 3 3 3 1 MULE transposase domain MULE PF10551.9 RLN96223.1 - 2.4e-16 59.9 3.8 5.3e-16 58.8 0.5 2.5 2 0 0 2 2 2 1 MULE transposase domain DUF3549 PF12069.8 RLN96223.1 - 0.027 13.5 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) DDE_Tnp_ISL3 PF01610.17 RLN96223.1 - 0.09 12.5 2.3 0.062 13.0 0.4 1.6 2 0 0 2 2 2 0 Transposase T2SSL PF05134.13 RLN96223.1 - 0.13 11.6 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein L MULE PF10551.9 RLN96227.1 - 1.2e-14 54.5 1.4 4.7e-14 52.6 1.3 2.0 2 1 0 2 2 2 1 MULE transposase domain zf-C2HC_2 PF13913.6 RLN96228.1 - 0.0025 17.6 3.5 0.0072 16.2 3.5 1.8 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 RLN96228.1 - 0.11 13.0 2.2 0.56 10.8 0.8 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 RLN96228.1 - 1.7 9.0 9.4 0.064 13.6 2.0 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Lactamase_B_6 PF16661.5 RLN96229.1 - 9.7e-45 152.4 0.0 1.6e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 RLN96229.1 - 5.2e-20 72.3 3.1 1.6e-17 64.2 0.0 3.2 2 1 1 3 3 3 2 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.12 RLN96229.1 - 5e-08 32.8 0.0 1.2e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 RLN96229.1 - 4e-06 27.0 0.2 6.8e-06 26.2 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 RLN96229.1 - 0.0039 16.7 0.1 0.016 14.7 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Zn-ribbon_8 PF09723.10 RLN96230.1 - 0.012 15.7 1.9 2.2 8.4 0.2 2.7 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 RLN96230.1 - 0.028 14.5 1.5 0.064 13.3 1.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 RLN96230.1 - 0.1 12.6 1.8 0.23 11.5 1.8 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 RLN96230.1 - 0.12 12.8 0.8 0.36 11.2 0.8 1.9 1 0 0 1 1 1 0 Restriction alleviation protein Lar YhfH PF14149.6 RLN96230.1 - 0.67 10.0 6.6 11 6.1 1.7 2.5 2 0 0 2 2 2 0 YhfH-like protein Oxysterol_BP PF01237.18 RLN96232.1 - 2.3e-37 128.7 0.0 1.5e-36 126.0 0.0 1.8 1 1 1 2 2 2 1 Oxysterol-binding protein SNARE_assoc PF09335.11 RLN96233.1 - 1e-11 45.3 2.3 2.3e-10 41.0 1.2 2.7 2 0 0 2 2 2 1 SNARE associated Golgi protein ParA PF10609.9 RLN96234.1 - 5.5e-57 193.0 0.4 7.3e-57 192.6 0.4 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 RLN96234.1 - 6.6e-12 45.6 0.0 9.6e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 RLN96234.1 - 2.1e-11 44.1 0.1 8.6e-10 38.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 RLN96234.1 - 1.4e-07 31.1 0.3 6.4e-07 28.9 0.3 2.0 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 RLN96234.1 - 2.5e-06 27.2 0.0 3.5e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 RLN96234.1 - 0.00026 20.3 0.4 0.00061 19.1 0.2 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 RLN96234.1 - 0.00038 19.8 0.0 0.0007 19.0 0.0 1.4 1 0 0 1 1 1 1 VirC1 protein CBP_BcsQ PF06564.12 RLN96234.1 - 0.0047 16.4 0.1 0.017 14.6 0.1 1.9 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 RLN96234.1 - 0.011 14.8 0.1 0.02 13.9 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 RLN96234.1 - 0.018 14.9 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop FeS_assembly_P PF01883.19 RLN96234.1 - 0.06 13.5 0.3 4.9 7.4 0.0 2.6 1 1 1 2 2 2 0 Iron-sulfur cluster assembly protein ParA PF10609.9 RLN96235.1 - 7.8e-08 32.1 0.0 7.8e-08 32.1 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Fis1_TPR_N PF14852.6 RLN96235.1 - 0.19 11.4 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat Pkinase PF00069.25 RLN96240.1 - 1e-61 208.6 0.0 1.5e-61 208.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN96240.1 - 1e-29 103.7 0.0 1.4e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN96240.1 - 0.0004 19.8 0.0 0.00059 19.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN96240.1 - 0.0044 16.4 0.2 0.0077 15.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN96240.1 - 0.0053 15.6 0.0 0.0095 14.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN96240.1 - 0.043 13.7 0.2 0.076 12.9 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 RLN96240.1 - 0.054 13.1 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 RLN96240.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Ribosomal_L19 PF01245.20 RLN96242.1 - 1.1e-19 70.4 1.7 5.8e-18 64.8 1.7 2.1 1 1 0 1 1 1 1 Ribosomal protein L19 Acyltransferase PF01553.21 RLN96243.1 - 3e-20 72.2 0.0 4.6e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 RLN96243.1 - 3.3e-12 46.3 0.0 6.7e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus CRT-like PF08627.10 RLN96244.1 - 2.7e-98 329.0 5.6 3.1e-98 328.8 5.6 1.0 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 RLN96244.1 - 2.2e-05 23.8 0.4 2.2e-05 23.8 0.4 1.7 2 0 0 2 2 2 1 UAA transporter family SLC35F PF06027.12 RLN96244.1 - 0.0026 17.3 2.4 0.0026 17.3 2.4 1.8 2 0 0 2 2 2 1 Solute carrier family 35 EamA PF00892.20 RLN96244.1 - 0.0073 16.5 4.0 0.0073 16.5 4.0 3.2 2 1 0 2 2 2 1 EamA-like transporter family LRR_4 PF12799.7 RLN96245.1 - 3.9e-10 39.8 0.0 1.4 9.4 0.0 7.7 7 3 1 8 8 8 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RLN96245.1 - 3.3e-09 36.1 16.7 1.7 8.9 0.0 11.1 14 0 0 14 14 14 4 Leucine Rich repeat IQ PF00612.27 RLN96245.1 - 3.3e-08 32.6 71.7 0.0091 15.7 0.8 12.6 11 0 0 11 11 11 7 IQ calmodulin-binding motif LRR_1 PF00560.33 RLN96245.1 - 2.7e-06 27.1 8.0 28 5.8 0.0 8.8 8 1 0 8 8 8 1 Leucine Rich Repeat LRR_2 PF07723.13 RLN96245.1 - 0.11 13.2 1.4 18 6.2 0.2 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat SRP_TPR_like PF17004.5 RLN96246.1 - 3.8e-07 30.1 0.5 1.2e-06 28.5 0.5 1.9 1 0 0 1 1 1 1 Putative TPR-like repeat SRP72 PF08492.12 RLN96246.1 - 2.6e-05 24.5 0.3 2.6e-05 24.5 0.3 2.6 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_12 PF13424.6 RLN96246.1 - 9.4e-05 22.6 25.1 0.0086 16.3 0.4 6.4 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 RLN96246.1 - 0.00054 20.4 17.4 3.9 8.3 0.2 7.3 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN96246.1 - 0.0035 17.4 12.6 0.62 10.4 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF4810 PF16068.5 RLN96246.1 - 0.0063 17.0 0.0 4 8.1 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4810) TPR_7 PF13176.6 RLN96246.1 - 0.0091 16.0 0.2 0.0091 16.0 0.2 5.2 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN96246.1 - 0.018 15.2 1.7 0.018 15.2 1.7 4.3 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RLN96246.1 - 0.034 15.0 29.3 0.29 12.1 0.3 7.6 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN96246.1 - 0.089 13.3 31.9 0.85 10.2 0.0 7.7 6 2 2 8 8 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 RLN96246.1 - 0.11 12.2 1.5 6.7 6.5 0.0 3.9 3 0 0 3 3 3 0 TPR repeat TPR_9 PF13371.6 RLN96246.1 - 0.18 11.9 5.4 1.3 9.2 1.3 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN96246.1 - 0.25 11.5 33.1 0.5 10.6 0.5 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_4 PF07721.14 RLN96246.1 - 0.27 12.0 16.4 2.4 9.1 0.2 7.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN96246.1 - 0.79 9.7 14.8 2.1 8.3 0.2 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-CCCH PF00642.24 RLN96247.1 - 2.1e-14 53.0 7.3 5.8e-07 29.3 0.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RLN96247.1 - 5.9e-10 38.9 11.9 7.6e-05 22.6 1.7 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-C2H2_jaz PF12171.8 RLN96247.1 - 6.5e-10 39.0 0.9 8.6e-07 29.1 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RLN96247.1 - 1.3e-08 34.9 2.4 4.4e-07 30.1 0.3 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-CCCH_4 PF18044.1 RLN96247.1 - 1.7e-08 34.1 8.9 0.00014 21.6 1.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-C2H2_2 PF12756.7 RLN96247.1 - 1.3e-06 28.6 5.6 0.0031 17.8 4.0 2.5 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 RLN96247.1 - 0.00046 20.5 2.4 0.035 14.6 0.3 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type Torus PF16131.5 RLN96247.1 - 0.002 18.8 16.1 0.018 15.8 4.9 3.0 2 1 1 3 3 2 2 Torus domain Dynamitin PF04912.14 RLN96247.1 - 0.0072 15.7 7.3 0.012 15.0 7.3 1.3 1 0 0 1 1 1 1 Dynamitin zf-C2H2_4 PF13894.6 RLN96247.1 - 0.01 16.6 0.8 0.19 12.6 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger TFIIF_alpha PF05793.12 RLN96247.1 - 0.038 12.6 9.8 0.049 12.2 9.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-CCCH_2 PF14608.6 RLN96247.1 - 0.1 13.1 10.0 0.35 11.4 1.5 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 RLN96247.1 - 0.34 11.2 11.4 1.1 9.5 6.9 3.2 1 1 1 2 2 2 0 Zinc-finger containing family zf-H2C2_2 PF13465.6 RLN96247.1 - 0.44 11.1 0.1 0.44 11.1 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double domain Striatin PF08232.12 RLN96247.1 - 2.2 8.8 15.4 0.78 10.3 8.8 2.2 2 0 0 2 2 2 0 Striatin family FUSC PF04632.12 RLN96247.1 - 5.8 5.3 5.3 0.63 8.5 1.2 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family Phosducin PF02114.16 RLN96248.1 - 1.4e-17 63.6 0.2 2.3e-17 62.8 0.2 1.3 1 1 0 1 1 1 1 Phosducin EarP PF10093.9 RLN96248.1 - 0.015 14.4 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 Elongation-Factor P (EF-P) rhamnosyltransferase EarP Arf PF00025.21 RLN96249.1 - 9.6e-30 103.3 0.0 1.1e-29 103.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 RLN96249.1 - 1.5e-06 27.6 0.0 1.8e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Roc PF08477.13 RLN96249.1 - 4e-06 27.1 0.0 6.5e-06 26.4 0.0 1.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 RLN96249.1 - 9.4e-05 21.9 0.0 0.00012 21.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 RLN96249.1 - 0.00017 21.2 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 RLN96249.1 - 0.00036 20.1 0.0 0.00064 19.3 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RLN96249.1 - 0.053 13.6 0.0 0.076 13.1 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase DEAD PF00270.29 RLN96250.1 - 8.1e-44 149.5 0.0 1.5e-43 148.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN96250.1 - 4.6e-26 91.4 0.0 2.2e-25 89.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN96250.1 - 0.00011 22.3 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 RLN96250.1 - 0.0017 17.8 0.2 0.0051 16.2 0.0 1.9 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Choline_transpo PF04515.12 RLN96251.1 - 5e-51 173.8 31.3 5e-51 173.8 31.3 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter PX PF00787.24 RLN96251.1 - 0.00079 19.4 0.2 0.0016 18.4 0.2 1.5 1 0 0 1 1 1 1 PX domain SHR3_chaperone PF08229.11 RLN96251.1 - 0.19 10.7 2.9 0.26 10.2 0.1 2.1 1 1 0 2 2 2 0 ER membrane protein SH3 EF-hand_7 PF13499.6 RLN96252.1 - 2.6e-37 127.1 23.6 4.5e-10 39.8 0.2 9.3 9 0 0 9 9 9 4 EF-hand domain pair EF-hand_1 PF00036.32 RLN96252.1 - 3.4e-30 101.3 21.7 0.00052 19.4 0.0 11.7 11 1 1 12 12 12 7 EF hand EF-hand_6 PF13405.6 RLN96252.1 - 1.5e-26 90.0 19.1 0.017 15.0 0.1 11.2 10 0 0 10 10 10 9 EF-hand domain EF-hand_8 PF13833.6 RLN96252.1 - 8.5e-22 76.8 19.6 2.5e-07 30.4 0.0 8.5 7 2 2 9 9 9 5 EF-hand domain pair EF-hand_5 PF13202.6 RLN96252.1 - 1.7e-14 52.5 20.4 0.0013 18.1 0.1 9.0 9 0 0 9 9 9 5 EF hand EF-hand_9 PF14658.6 RLN96252.1 - 4.9e-11 42.8 5.1 0.0032 17.8 0.0 7.3 8 0 0 8 8 8 2 EF-hand domain EF-hand_11 PF08976.11 RLN96252.1 - 1.9e-08 35.1 0.8 0.03 15.2 0.0 6.3 6 0 0 6 6 6 1 EF-hand domain EF-hand_4 PF12763.7 RLN96252.1 - 4e-05 23.5 0.7 0.038 13.9 0.0 5.4 6 0 0 6 6 6 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 RLN96252.1 - 0.0027 17.9 0.4 0.19 12.0 0.0 3.4 3 0 0 3 3 2 1 Dockerin type I domain LRR_6 PF13516.6 RLN96252.1 - 0.026 14.6 0.5 0.39 10.9 0.2 2.7 2 0 0 2 2 2 0 Leucine Rich repeat TerB PF05099.13 RLN96252.1 - 2.1 8.3 6.3 9.2 6.2 0.0 4.8 7 0 0 7 7 7 0 Tellurite resistance protein TerB 5_nucleotid_C PF02872.18 RLN96254.1 - 2e-21 76.9 0.0 3.6e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 RLN96254.1 - 9.6e-09 36.0 0.1 1.8e-08 35.1 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CBM9_2 PF16011.5 RLN96254.1 - 1.3e-05 25.0 0.0 2.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate-binding family 9 CBM9_1 PF06452.11 RLN96254.1 - 0.0009 19.2 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate family 9 binding domain-like Tat PF00539.18 RLN96255.1 - 1.1 9.4 4.4 4.5 7.5 4.4 2.0 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) TPR_MLP1_2 PF07926.12 RLN96256.1 - 0.013 15.5 6.9 0.023 14.8 6.9 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Troponin PF00992.20 RLN96256.1 - 0.031 14.6 1.2 0.053 13.8 1.2 1.4 1 0 0 1 1 1 0 Troponin KI67R PF08065.12 RLN96256.1 - 0.08 13.5 1.1 0.12 12.9 1.1 1.3 1 0 0 1 1 1 0 KI67R (NUC007) repeat SlyX PF04102.12 RLN96256.1 - 0.085 13.5 1.1 0.8 10.4 0.2 2.4 1 1 1 2 2 2 0 SlyX Spc7 PF08317.11 RLN96256.1 - 0.094 11.6 3.8 0.11 11.3 3.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TolA_bind_tri PF16331.5 RLN96256.1 - 0.11 12.6 2.6 1.7 8.8 0.3 2.4 1 1 1 2 2 2 0 TolA binding protein trimerisation Phage_GP20 PF06810.11 RLN96256.1 - 0.13 12.0 1.2 0.21 11.4 1.2 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 Cnn_1N PF07989.11 RLN96256.1 - 0.2 11.9 3.2 1.1 9.5 0.6 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DASH_Dam1 PF08653.10 RLN96256.1 - 0.33 10.8 1.5 0.76 9.6 0.5 2.1 2 0 0 2 2 2 0 DASH complex subunit Dam1 ADIP PF11559.8 RLN96256.1 - 0.69 10.0 7.2 0.32 11.1 5.2 1.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 RLN96256.1 - 2.3 8.7 8.1 2.7 8.5 6.6 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region Ribosomal_S26e PF01283.19 RLN96259.1 - 2.4e-23 82.6 1.3 2.5e-23 82.6 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e MutS_V PF00488.21 RLN96262.1 - 1.5e-67 227.3 0.1 2.7e-67 226.5 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 RLN96262.1 - 9.4e-20 71.6 2.5 2.5e-19 70.3 2.5 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 RLN96262.1 - 2.4e-14 53.8 0.0 6.5e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 RLN96262.1 - 1.4e-10 41.4 0.1 3.8e-10 40.0 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 RLN96262.1 - 1.1e-05 25.6 0.0 3.6e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 MutS domain I Sugar_tr PF00083.24 RLN96263.1 - 9.5e-23 80.8 14.7 1.2e-22 80.5 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN96263.1 - 2.4e-11 43.2 1.7 2.8e-11 43.0 1.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily AAA PF00004.29 RLN96264.1 - 3.7e-31 108.3 0.1 1.1e-30 106.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN96264.1 - 1.4e-08 35.1 0.0 7.3e-08 32.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN96264.1 - 5.5e-07 30.1 0.0 1.8e-06 28.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 RLN96264.1 - 1.9e-05 24.6 0.1 3.4e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 RLN96264.1 - 3.6e-05 24.3 0.0 7.5e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RLN96264.1 - 0.0003 21.0 0.1 0.00069 19.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 RLN96264.1 - 0.0006 19.8 0.0 0.0032 17.4 0.0 2.0 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 RLN96264.1 - 0.00081 19.2 0.0 0.0023 17.7 0.0 1.7 1 1 0 1 1 1 1 Cytidylate kinase ATPase PF06745.13 RLN96264.1 - 0.00089 18.7 0.1 1.2 8.5 0.0 2.4 2 0 0 2 2 2 2 KaiC TsaE PF02367.17 RLN96264.1 - 0.001 19.0 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 RLN96264.1 - 0.0015 18.8 0.0 0.0066 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 RLN96264.1 - 0.0016 18.3 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RLN96264.1 - 0.0024 17.9 0.2 0.0075 16.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 RLN96264.1 - 0.0024 17.7 0.0 0.0043 16.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RLN96264.1 - 0.003 17.3 0.0 0.0077 16.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 RLN96264.1 - 0.003 17.2 0.1 0.22 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RLN96264.1 - 0.0046 16.7 0.0 0.017 14.9 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 RLN96264.1 - 0.0054 16.8 0.5 0.16 12.0 0.2 2.6 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RLN96264.1 - 0.0059 16.1 0.0 0.038 13.5 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 RLN96264.1 - 0.0065 16.9 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.6 RLN96264.1 - 0.012 16.0 0.1 0.054 13.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 RLN96264.1 - 0.014 14.6 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain DUF815 PF05673.13 RLN96264.1 - 0.017 14.3 0.2 0.2 10.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_2 PF07724.14 RLN96264.1 - 0.032 14.3 0.0 0.11 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 RLN96264.1 - 0.048 13.4 0.0 0.093 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 RLN96264.1 - 0.049 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_3 PF07726.11 RLN96264.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 RLN96264.1 - 0.068 13.6 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RLN96264.1 - 0.073 13.6 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.16 RLN96264.1 - 0.08 12.4 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein KAP_NTPase PF07693.14 RLN96264.1 - 0.086 12.1 0.1 13 4.9 0.1 2.2 1 1 0 2 2 2 0 KAP family P-loop domain CPT PF07931.12 RLN96264.1 - 0.094 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Mg_chelatase PF01078.21 RLN96264.1 - 0.1 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.9 RLN96264.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.18 RLN96264.1 - 0.13 12.0 0.1 0.45 10.2 0.0 1.8 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase AAT PF03417.16 RLN96266.1 - 8.1e-24 84.6 0.0 1.2e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Uteroglobin PF01099.17 RLN96266.1 - 0.079 13.3 0.0 0.44 10.9 0.0 2.0 2 0 0 2 2 2 0 Uteroglobin family DnaJ PF00226.31 RLN96267.1 - 5.9e-26 90.4 0.3 9.6e-26 89.7 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain ABC_membrane PF00664.23 RLN96268.1 - 1.6e-57 195.2 0.3 2e-57 195.0 0.3 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF3007 PF11460.8 RLN96268.1 - 0.0018 18.5 1.4 0.069 13.4 0.3 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3007) FAM177 PF14774.6 RLN96269.1 - 2e-09 37.8 0.1 3.9e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 FAM177 family DUF1151 PF06625.11 RLN96269.1 - 0.056 13.4 9.1 0.064 13.2 9.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) DUF1682 PF07946.14 RLN96269.1 - 1.6 7.9 11.5 1.9 7.6 11.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) tRNA-synt_His PF13393.6 RLN96270.1 - 5.5e-08 32.4 2.4 1.3e-06 28.0 0.1 2.3 1 1 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 RLN96270.1 - 0.0031 17.6 0.0 0.0061 16.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain DUF3847 PF12958.7 RLN96270.1 - 0.059 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) Fer4_15 PF13459.6 RLN96272.1 - 2.4 9.0 5.7 0.35 11.6 0.8 2.2 2 0 0 2 2 2 0 4Fe-4S single cluster domain PX PF00787.24 RLN96273.1 - 6.6e-05 22.9 0.0 8.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 PX domain DUF3797 PF12677.7 RLN96273.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) ABC_tran PF00005.27 RLN96274.1 - 3.3e-25 89.2 0.0 5.3e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 RLN96274.1 - 6.5e-10 39.1 2.1 9.1e-10 38.6 2.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 RLN96274.1 - 5.8e-06 25.9 2.0 0.00072 19.1 0.4 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RLN96274.1 - 0.0071 16.4 0.2 0.017 15.2 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 RLN96274.1 - 0.02 14.7 0.2 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 RLN96274.1 - 0.051 13.5 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 RLN96274.1 - 0.081 13.2 0.2 1 9.6 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 RLN96274.1 - 0.085 12.7 0.7 2.1 8.1 0.4 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 RLN96274.1 - 0.089 12.8 0.1 9.7 6.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 RLN96274.1 - 0.29 11.2 0.6 0.66 10.0 0.6 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain DEAD PF00270.29 RLN96274.1 - 0.3 10.8 2.6 3.3 7.5 2.6 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase ABC_membrane PF00664.23 RLN96275.1 - 1.5e-50 172.4 19.6 4.4e-26 92.1 3.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN96275.1 - 2.4e-46 157.6 0.0 9.5e-24 84.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN96275.1 - 1.7e-08 34.2 1.5 0.033 13.6 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RLN96275.1 - 7.5e-05 23.2 0.6 0.013 15.9 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 RLN96275.1 - 0.0002 21.3 0.7 0.39 10.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RLN96275.1 - 0.001 19.1 0.3 0.81 9.8 0.2 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RNA_helicase PF00910.22 RLN96275.1 - 0.0029 18.0 1.1 0.82 10.1 0.1 3.6 3 0 0 3 3 3 1 RNA helicase AAA_21 PF13304.6 RLN96275.1 - 0.0038 17.1 0.3 21 4.8 0.0 3.8 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 RLN96275.1 - 0.0043 16.8 1.3 2.9 7.6 0.0 3.5 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_29 PF13555.6 RLN96275.1 - 0.014 15.2 1.3 3.5 7.4 0.3 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN96275.1 - 0.036 14.4 3.1 0.33 11.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 RLN96275.1 - 0.053 12.7 0.5 0.6 9.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Roc PF08477.13 RLN96275.1 - 0.11 12.7 0.3 18 5.6 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 RLN96275.1 - 0.13 12.3 0.4 2.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP-synt_ab PF00006.25 RLN96275.1 - 0.13 11.8 0.1 15 5.1 0.0 2.6 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 RLN96275.1 - 0.16 12.4 2.6 0.7 10.3 0.0 3.0 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 RLN96275.1 - 0.16 11.7 0.3 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 RLN96275.1 - 0.23 11.5 0.7 4.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 RLN96275.1 - 0.31 11.6 1.0 2.7 8.6 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 RLN96275.1 - 0.36 10.4 1.5 3.5 7.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 RLN96275.1 - 0.7 9.9 2.0 5.2 7.1 0.4 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain DMRT-like PF15791.5 RLN96276.1 - 0.023 15.1 1.1 0.08 13.4 1.1 1.9 1 0 0 1 1 1 0 Doublesex-and mab-3-related transcription factor C1 and C2 PGA_cap PF09587.10 RLN96276.1 - 0.11 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap ABC_membrane PF00664.23 RLN96277.1 - 1.9e-24 86.8 9.6 2.3e-24 86.5 9.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN96277.1 - 1.5e-07 32.0 0.1 3.1e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 RLN96277.1 - 0.01 16.3 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 RLN96277.1 - 0.05 13.5 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 RLN96277.1 - 0.067 13.5 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 RLN96277.1 - 0.09 11.9 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA PF00004.29 RLN96277.1 - 0.16 12.4 0.1 0.34 11.3 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sugar_tr PF00083.24 RLN96278.1 - 9.4e-94 314.8 21.3 1.3e-93 314.3 21.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN96278.1 - 3.2e-27 95.4 59.1 8.5e-25 87.4 34.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 RLN96278.1 - 0.011 14.2 9.7 0.042 12.2 0.4 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Sugar_tr PF00083.24 RLN96279.1 - 1.3e-91 307.8 23.3 1.6e-91 307.5 23.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN96279.1 - 1.1e-25 90.3 29.8 1.1e-25 90.3 29.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 RLN96279.1 - 1.5e-05 23.6 1.8 1.5e-05 23.6 1.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3188 PF11384.8 RLN96279.1 - 0.0042 16.8 0.5 0.0042 16.8 0.5 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3188) 3HCDH_N PF02737.18 RLN96280.1 - 3.6e-09 36.8 0.0 1.3e-06 28.4 0.0 2.1 1 1 1 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sugar_tr PF00083.24 RLN96281.1 - 1.2e-167 558.3 39.3 5e-92 309.1 18.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RLN96281.1 - 5.5e-37 127.5 59.8 6.2e-24 84.6 27.4 3.5 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF2583 PF10762.9 RLN96281.1 - 1.8 9.0 17.8 2.9 8.4 5.0 3.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2583) Sugar_tr PF00083.24 RLN96282.1 - 9e-19 67.6 11.3 9.7e-19 67.5 11.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3450 PF11932.8 RLN96284.1 - 0.51 9.6 13.2 0.088 12.1 6.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) YabA PF06156.13 RLN96284.1 - 0.56 10.9 3.2 2.5 8.8 0.1 2.4 2 0 0 2 2 2 0 Initiation control protein YabA Com_YlbF PF06133.11 RLN96284.1 - 1.5 9.5 8.0 6.1 7.5 0.7 2.6 3 0 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA CENP-F_leu_zip PF10473.9 RLN96284.1 - 2.4 8.2 13.6 24 5.0 11.9 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DDE_1 PF03184.19 RLN96285.1 - 6.1e-12 45.5 0.0 8.4e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Arf PF00025.21 RLN96286.1 - 6.5e-21 74.5 0.0 1e-20 73.9 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 RLN96286.1 - 5.5e-05 22.8 0.0 6.8e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 RLN96286.1 - 0.017 14.3 0.0 0.022 14.0 0.0 1.0 1 0 0 1 1 1 0 G-protein alpha subunit SRPRB PF09439.10 RLN96286.1 - 0.02 14.3 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 RLN96286.1 - 0.18 12.1 0.0 0.31 11.2 0.0 1.5 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase COLFI PF01410.18 RLN96287.1 - 0.074 12.3 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Fibrillar collagen C-terminal domain Ribosomal_S5_C PF03719.15 RLN96288.1 - 1.2e-22 79.1 0.0 2.1e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 RLN96288.1 - 9.8e-17 60.7 0.0 2.4e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Peptidase_M24 PF00557.24 RLN96289.1 - 4.5e-33 114.7 0.0 5.5e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 KASH_CCD PF14662.6 RLN96289.1 - 0.081 12.7 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH RNA_polI_A34 PF08208.11 RLN96289.1 - 0.3 11.2 10.4 0.46 10.5 10.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 HEAT PF02985.22 RLN96290.1 - 0.00064 19.8 0.3 0.076 13.3 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 RLN96290.1 - 0.0054 17.2 5.6 0.034 14.7 0.0 4.3 3 1 2 5 5 5 1 HEAT-like repeat HBS1_N PF08938.10 RLN96290.1 - 0.08 13.3 3.6 0.081 13.2 0.3 2.2 2 0 0 2 2 2 0 HBS1 N-terminus HEAT_2 PF13646.6 RLN96290.1 - 0.087 13.2 0.1 1.1 9.8 0.1 2.6 2 1 1 3 3 3 0 HEAT repeats Fis1_TPR_C PF14853.6 RLN96291.1 - 1.3e-12 47.6 0.1 3.3e-12 46.3 0.1 1.7 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TRAM_LAG1_CLN8 PF03798.16 RLN96291.1 - 5.9e-10 39.2 6.6 8e-10 38.8 6.6 1.2 1 0 0 1 1 1 1 TLC domain TPR_2 PF07719.17 RLN96291.1 - 0.0081 16.2 0.0 0.0081 16.2 0.0 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_N PF14852.6 RLN96291.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat TPR_8 PF13181.6 RLN96291.1 - 0.076 13.3 0.4 0.22 11.8 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 RLN96292.1 - 2.9e-73 246.5 0.0 3.4e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN96292.1 - 2.2e-40 138.6 0.0 2.8e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN96292.1 - 2e-06 27.3 0.0 2.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RLN96292.1 - 0.0024 16.9 0.2 0.0034 16.4 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RLN96292.1 - 0.12 12.2 0.0 0.26 11.2 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.32 RLN96293.1 - 4.4e-06 27.3 12.2 0.096 13.6 0.1 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat Peptidase_S15 PF02129.18 RLN96294.1 - 1.4e-54 185.5 3.1 2.2e-54 184.9 3.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 RLN96294.1 - 1.2e-33 117.0 0.5 2.6e-33 115.9 0.0 1.7 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 RLN96294.1 - 1.6e-09 37.4 0.0 3.5e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 RLN96294.1 - 1.1e-06 28.3 1.2 2e-06 27.4 0.6 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 RLN96294.1 - 2.2e-06 27.5 0.3 4.9e-06 26.4 0.3 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1579 PF07617.11 RLN96294.1 - 0.068 13.1 0.1 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1579) Abhydrolase_6 PF12697.7 RLN96294.1 - 0.07 13.7 6.5 0.12 12.9 6.2 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family NAD_binding_10 PF13460.6 RLN96295.1 - 0.026 14.4 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H-binding RIFIN PF02009.16 RLN96297.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Rifin EF-hand_6 PF13405.6 RLN96298.1 - 6.8e-08 31.8 0.5 0.0019 18.0 0.0 3.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RLN96298.1 - 6.5e-06 26.5 0.8 5.4e-05 23.6 0.0 2.9 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN96298.1 - 0.00014 21.1 0.1 1 9.0 0.0 3.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RLN96298.1 - 0.0048 16.7 0.2 0.088 12.7 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair TMF_DNA_bd PF12329.8 RLN96298.1 - 0.038 14.0 6.4 0.21 11.6 6.4 2.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Rap_GAP PF02145.15 RLN96299.1 - 3.1e-55 186.6 0.0 5.3e-55 185.9 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP RGS PF00615.19 RLN96299.1 - 0.0019 18.4 0.1 0.0062 16.8 0.0 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain DUF3402 PF11882.8 RLN96300.1 - 5.1e-05 22.6 5.1 0.0002 20.6 1.7 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) Bro-N PF02498.17 RLN96301.1 - 0.00021 21.9 0.1 0.0014 19.2 0.0 2.3 2 0 0 2 2 2 1 BRO family, N-terminal domain Golgin_A5 PF09787.9 RLN96301.1 - 0.013 15.0 5.0 0.017 14.6 5.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 AAA_25 PF13481.6 RLN96303.1 - 0.0097 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.7 RLN96303.1 - 0.059 12.3 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain RsgA_GTPase PF03193.16 RLN96303.1 - 0.063 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase DHHC PF01529.20 RLN96305.1 - 0.0024 18.0 1.4 0.0024 18.0 1.4 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase Pkinase PF00069.25 RLN96306.1 - 6.6e-32 110.9 0.0 2.3e-23 82.9 0.0 5.5 4 2 2 6 6 6 3 Protein kinase domain Pkinase_Tyr PF07714.17 RLN96306.1 - 1e-29 103.7 0.0 1.2e-19 70.7 0.0 4.3 2 2 2 4 4 4 3 Protein tyrosine kinase KfrA_N PF11740.8 RLN96306.1 - 1.8 9.3 7.5 1.2 9.8 0.1 3.1 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term PhzC-PhzF PF02567.16 RLN96307.1 - 1.3e-57 195.5 0.1 1.6e-57 195.1 0.1 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Acetyltransf_1 PF00583.25 RLN96307.1 - 3.3e-10 40.2 0.0 7.1e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RLN96307.1 - 1.6e-09 37.8 0.1 3.6e-09 36.6 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN96307.1 - 1.8e-08 34.7 0.1 4.8e-08 33.3 0.1 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 RLN96307.1 - 0.0025 17.9 0.0 0.0046 17.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 RLN96307.1 - 0.011 15.9 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 RLN96307.1 - 0.017 15.1 0.0 0.079 12.9 0.0 2.1 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Acetyltransf_15 PF17013.5 RLN96307.1 - 0.098 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase HTH_3 PF01381.22 RLN96307.1 - 0.1 12.7 0.0 2.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix DHOase PF12890.7 RLN96307.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Dihydro-orotase-like Asn_synthase PF00733.21 RLN96308.1 - 6.9e-19 68.7 2.5 9.3e-09 35.4 0.2 3.2 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 RLN96308.1 - 2.3e-08 34.0 0.0 8.6e-08 32.1 0.0 2.0 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 RLN96308.1 - 0.0013 18.9 0.0 0.0049 17.1 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain Orai-1 PF07856.12 RLN96311.1 - 1.8e-21 76.6 7.2 2.6e-21 76.1 7.2 1.2 1 0 0 1 1 1 1 Mediator of CRAC channel activity Hydrolase_4 PF12146.8 RLN96312.1 - 6.1e-51 173.0 0.0 9.1e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN96312.1 - 3.7e-13 50.6 2.2 5e-13 50.2 2.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN96312.1 - 1.3e-07 31.6 0.3 7.8e-05 22.4 0.3 2.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 RLN96312.1 - 0.00011 22.0 0.0 3.1 7.6 0.0 3.1 3 0 0 3 3 3 3 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 RLN96312.1 - 0.0036 16.8 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 RLN96312.1 - 0.03 13.9 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase PF00756.20 RLN96312.1 - 0.038 13.6 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase FYVE PF01363.21 RLN96313.1 - 0.00022 21.3 6.4 0.00049 20.2 6.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN96313.1 - 0.0017 18.5 5.0 0.0035 17.5 5.0 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger GAF_2 PF13185.6 RLN96313.1 - 0.011 16.0 0.0 0.042 14.1 0.0 2.0 1 0 0 1 1 1 0 GAF domain FANCL_C PF11793.8 RLN96313.1 - 0.9 9.8 4.4 13 6.1 4.3 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 RLN96313.1 - 3.1 7.7 10.0 38 4.3 10.0 2.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DUF4045 PF13254.6 RLN96314.1 - 2.3 7.8 13.6 2.4 7.7 13.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Filament PF00038.21 RLN96316.1 - 3.1e-22 79.6 48.3 7e-22 78.4 48.3 2.0 1 1 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 RLN96316.1 - 3.4e-09 37.0 0.0 7.8e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Lamin Tail Domain HIP1_clath_bdg PF16515.5 RLN96316.1 - 0.023 15.3 8.6 0.023 15.3 8.6 4.9 2 1 2 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Prominin PF05478.11 RLN96316.1 - 0.33 8.8 17.2 0.46 8.4 17.2 1.2 1 0 0 1 1 1 0 Prominin HMMR_N PF15905.5 RLN96316.1 - 3.9 6.8 49.8 0.14 11.6 13.0 3.9 2 1 2 4 4 4 0 Hyaluronan mediated motility receptor N-terminal DUF4407 PF14362.6 RLN96316.1 - 4.5 6.5 39.1 0.65 9.3 8.6 4.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) WXG100 PF06013.12 RLN96316.1 - 7.8 6.8 13.6 1.6 9.0 0.6 4.9 3 2 2 5 5 5 0 Proteins of 100 residues with WXG Aminotran_4 PF01063.19 RLN96318.1 - 6.4e-19 68.7 0.0 7.7e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Aminotran_4 PF01063.19 RLN96319.1 - 0.00026 20.9 0.0 0.00035 20.5 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Agenet PF05641.12 RLN96321.1 - 6.9e-05 23.2 21.4 0.37 11.3 0.1 6.2 7 0 0 7 7 7 4 Agenet domain Tudor_3 PF18115.1 RLN96321.1 - 0.027 14.3 0.2 0.37 10.7 0.0 2.6 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain PilZ PF07238.14 RLN96321.1 - 0.046 14.0 0.6 38 4.7 0.0 3.8 3 0 0 3 3 3 0 PilZ domain LBR_tudor PF09465.10 RLN96321.1 - 0.24 11.2 1.2 0.7 9.7 0.0 2.5 3 0 0 3 3 3 0 Lamin-B receptor of TUDOR domain Arf PF00025.21 RLN96322.1 - 3.4e-11 42.9 0.4 0.00071 19.1 0.1 3.2 3 0 0 3 3 3 2 ADP-ribosylation factor family G-alpha PF00503.20 RLN96322.1 - 0.00018 20.8 0.0 0.11 11.6 0.1 2.6 3 0 0 3 3 3 2 G-protein alpha subunit MMR_HSR1 PF01926.23 RLN96322.1 - 0.00081 19.5 0.0 0.0021 18.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 RLN96322.1 - 0.014 16.0 0.0 0.035 14.6 0.0 1.7 2 0 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 RLN96322.1 - 0.019 14.9 0.3 1 9.2 0.1 2.5 3 0 0 3 3 3 0 RsgA GTPase AAA_16 PF13191.6 RLN96322.1 - 0.021 15.2 0.4 0.041 14.3 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 RLN96322.1 - 0.023 14.9 0.1 0.093 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 RLN96322.1 - 0.043 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 RLN96322.1 - 0.078 12.3 0.0 3.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_18 PF13238.6 RLN96322.1 - 0.17 12.5 0.0 0.33 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 RLN96322.1 - 0.24 11.0 0.1 2 7.9 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PEPCK_ATP PF01293.20 RLN96322.1 - 0.25 10.0 0.1 0.38 9.4 0.1 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase OKR_DC_1_C PF03711.15 RLN96324.1 - 0.028 14.7 0.4 3.3 8.0 0.4 2.8 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, C-terminal domain Anp1 PF03452.14 RLN96327.1 - 9.3e-33 113.8 2.2 4.9e-24 85.2 0.8 2.1 1 1 1 2 2 2 2 Anp1 Hexapep PF00132.24 RLN96328.1 - 6e-20 70.1 22.6 3.9e-07 29.5 0.5 5.9 5 1 1 6 6 6 5 Bacterial transferase hexapeptide (six repeats) Acetyltransf_11 PF13720.6 RLN96328.1 - 1.7e-14 54.0 0.0 2.8e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Hexapep_2 PF14602.6 RLN96328.1 - 9.7e-05 22.0 16.3 1.9 8.3 0.8 6.4 4 3 2 6 6 6 4 Hexapeptide repeat of succinyl-transferase Bactofilin PF04519.13 RLN96328.1 - 0.0035 17.6 5.9 0.012 15.9 2.1 2.5 2 1 0 2 2 2 1 Polymer-forming cytoskeletal WD40 PF00400.32 RLN96329.1 - 6.8e-06 26.7 0.3 0.0025 18.6 0.1 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Kinesin PF00225.23 RLN96330.1 - 2.4e-90 302.9 0.9 3.9e-90 302.2 0.3 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RLN96330.1 - 8.6e-20 71.2 0.1 2e-14 53.7 0.0 2.6 1 1 1 2 2 2 2 Microtubule binding BST2 PF16716.5 RLN96330.1 - 0.18 12.4 0.1 0.18 12.4 0.1 2.8 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Shugoshin_N PF07558.11 RLN96330.1 - 0.2 11.5 4.5 7 6.6 0.6 2.7 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF4618 PF15397.6 RLN96330.1 - 0.22 10.9 1.4 1.3 8.4 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) PspB PF06667.12 RLN96330.1 - 0.37 10.9 1.1 1.1 9.3 1.1 1.9 1 0 0 1 1 1 0 Phage shock protein B Anp1 PF03452.14 RLN96331.1 - 3e-41 141.6 0.4 1.2e-40 139.6 0.4 1.8 1 1 0 1 1 1 1 Anp1 Rho_RNA_bind PF07497.12 RLN96331.1 - 0.021 14.7 0.0 0.051 13.4 0.0 1.6 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain Abhydrolase_6 PF12697.7 RLN96332.1 - 3.4e-09 37.6 0.0 4.3e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN96332.1 - 0.00016 21.0 0.0 0.00024 20.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 ABC2_membrane PF01061.24 RLN96333.1 - 8.6e-66 221.3 59.1 3.3e-36 124.7 25.8 3.1 4 0 0 4 4 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN96333.1 - 3.3e-35 121.6 0.2 1.2e-16 61.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 RLN96333.1 - 4.1e-12 45.8 1.8 8.8e-11 41.6 0.0 3.5 2 1 0 2 2 2 1 CDR ABC transporter RsgA_GTPase PF03193.16 RLN96333.1 - 6.9e-08 32.6 0.5 0.004 17.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase ABC2_membrane_3 PF12698.7 RLN96333.1 - 1e-07 31.4 10.8 1e-07 31.4 10.8 3.7 3 1 1 4 4 4 2 ABC-2 family transporter protein AAA_21 PF13304.6 RLN96333.1 - 5.2e-07 29.8 0.0 0.57 9.9 0.0 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN96333.1 - 7.7e-06 26.4 1.3 0.035 14.5 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 RLN96333.1 - 2.2e-05 24.1 7.7 0.024 14.4 1.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN96333.1 - 0.00011 21.8 0.1 0.15 11.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RLN96333.1 - 0.00014 22.2 0.2 0.46 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RLN96333.1 - 0.0003 21.4 1.0 0.44 11.0 0.1 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 RLN96333.1 - 0.00031 20.3 2.7 1.5 8.2 0.2 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RLN96333.1 - 0.00086 19.4 0.9 0.23 11.5 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 RLN96333.1 - 0.0012 18.6 0.4 1.3 8.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 RLN96333.1 - 0.0027 18.1 0.7 4.8 7.6 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 RLN96333.1 - 0.0051 16.1 2.0 0.24 10.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 RLN96333.1 - 0.0069 16.9 0.0 3.3 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 RLN96333.1 - 0.0096 15.5 1.5 0.82 9.2 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.9 RLN96333.1 - 0.02 13.7 0.8 0.81 8.4 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Roc PF08477.13 RLN96333.1 - 0.038 14.2 0.6 5.7 7.2 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 RLN96333.1 - 0.048 13.6 3.7 5.2 7.0 0.6 2.6 2 0 0 2 2 2 0 NACHT domain Ploopntkinase3 PF18751.1 RLN96333.1 - 0.052 13.5 0.4 0.74 9.7 0.1 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 RLN96333.1 - 0.058 13.8 0.7 6.6 7.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 RLN96333.1 - 0.065 13.2 0.6 2.3 8.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Gtr1_RagA PF04670.12 RLN96333.1 - 0.077 12.3 1.6 2.3 7.5 0.1 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region ATPase_2 PF01637.18 RLN96333.1 - 0.081 12.8 0.0 5.6 6.8 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PDR_assoc PF08370.11 RLN96333.1 - 0.089 12.6 0.1 0.089 12.6 0.1 4.7 5 0 0 5 5 3 0 Plant PDR ABC transporter associated Rad17 PF03215.15 RLN96333.1 - 0.089 12.7 0.1 5.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain DUF87 PF01935.17 RLN96333.1 - 0.12 12.5 4.7 1.8 8.6 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_19 PF13245.6 RLN96333.1 - 0.12 12.7 0.0 25 5.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 RLN96333.1 - 0.14 12.4 0.2 13 6.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 RLN96333.1 - 0.21 10.8 0.1 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 RLN96333.1 - 0.25 10.7 1.5 5.4 6.3 0.1 2.6 2 0 0 2 2 2 0 KaiC PduV-EutP PF10662.9 RLN96333.1 - 0.28 10.9 2.3 4 7.2 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 RLN96333.1 - 0.32 10.7 2.7 13 5.4 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RLN96333.1 - 0.47 10.7 2.1 28 4.9 1.1 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 RLN96333.1 - 1.1 9.2 4.4 15 5.4 0.1 3.2 3 0 0 3 3 3 0 NTPase Guanylate_cyc PF00211.20 RLN96334.1 - 3.2e-09 36.7 0.0 6.1e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain RVT_1 PF00078.27 RLN96335.1 - 6.1e-17 61.9 0.1 5.7e-11 42.4 0.0 3.1 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Telomerase_RBD PF12009.8 RLN96335.1 - 8e-06 26.0 0.4 7.8e-05 22.8 0.4 2.5 1 1 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain DUF2205 PF10224.9 RLN96337.1 - 0.039 13.9 2.0 0.089 12.8 2.0 1.7 1 0 0 1 1 1 0 Short coiled-coil protein DUF2205 PF10224.9 RLN96338.1 - 0.1 12.6 1.4 0.28 11.2 1.4 1.8 1 0 0 1 1 1 0 Short coiled-coil protein DUF3138 PF11336.8 RLN96338.1 - 0.39 9.3 4.1 0.59 8.7 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CLU PF13236.6 RLN96339.1 - 1.3e-79 267.1 0.0 1.4e-78 263.8 0.0 2.2 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.7 RLN96339.1 - 1.4e-37 129.4 0.0 3.6e-37 128.1 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 RLN96339.1 - 1.1e-07 32.1 12.3 1.5e-07 31.6 7.6 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 RLN96339.1 - 0.0035 16.8 5.8 0.0035 16.8 5.8 1.6 2 0 0 2 2 2 1 MalT-like TPR region TPR_10 PF13374.6 RLN96339.1 - 0.02 14.7 0.2 0.02 14.7 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Myc_N PF01056.18 RLN96339.1 - 0.036 14.0 4.1 0.059 13.3 4.1 1.3 1 0 0 1 1 1 0 Myc amino-terminal region DUF4746 PF15928.5 RLN96339.1 - 0.045 13.2 5.4 0.078 12.4 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Afi1 PF07792.12 RLN96339.1 - 0.13 12.8 2.2 0.28 11.7 2.2 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking TPR_1 PF00515.28 RLN96339.1 - 0.67 9.9 3.5 42 4.2 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3987 PF13148.6 RLN96339.1 - 0.85 8.6 9.9 1.7 7.6 9.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Vfa1 PF08432.10 RLN96339.1 - 1.6 9.0 9.0 3.7 7.8 9.0 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PPP4R2 PF09184.11 RLN96339.1 - 3.8 7.0 10.8 6.4 6.3 10.8 1.3 1 0 0 1 1 1 0 PPP4R2 Ank_2 PF12796.7 RLN96340.1 - 5.2e-61 203.2 8.4 3.2e-12 46.9 1.5 5.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN96340.1 - 4.3e-52 173.8 6.5 1.1e-10 41.8 0.0 7.6 4 3 3 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN96340.1 - 7.5e-46 148.8 5.2 0.00027 21.1 0.0 10.7 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 RLN96340.1 - 2.4e-44 148.8 15.7 5.3e-09 36.2 0.1 9.0 2 2 6 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 RLN96340.1 - 3e-42 141.3 13.7 6.9e-06 26.3 0.0 10.4 10 0 0 10 10 10 8 Ankyrin repeat Pkinase_Tyr PF07714.17 RLN96340.1 - 1.3e-41 142.7 0.0 1.8e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN96340.1 - 3.8e-38 131.4 0.0 5.6e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Mub_B2 PF17966.1 RLN96340.1 - 0.041 14.6 0.2 0.25 12.1 0.1 2.3 3 0 0 3 3 3 0 Mub B2-like domain Pyr_redox_2 PF07992.14 RLN96348.1 - 2.3e-41 141.9 0.0 3.9e-41 141.2 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RLN96348.1 - 0.00066 20.2 0.5 0.004 17.7 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RLN96348.1 - 0.019 14.1 0.0 0.24 10.5 0.0 2.2 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF4459 PF14673.6 RLN96348.1 - 0.044 13.7 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4459) NAD_binding_9 PF13454.6 RLN96348.1 - 0.084 12.9 0.0 7.5 6.5 0.0 3.5 3 1 1 4 4 4 0 FAD-NAD(P)-binding DAO PF01266.24 RLN96348.1 - 0.12 12.0 0.2 10 5.6 0.0 2.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase GlcNAc PF11397.8 RLN96349.1 - 4.9e-46 157.8 0.2 7.8e-39 134.1 0.1 2.2 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Glycos_transf_2 PF00535.26 RLN96349.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 AAA PF00004.29 RLN96351.1 - 7.4e-41 139.7 0.0 1.5e-40 138.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RLN96351.1 - 4.2e-11 42.5 0.0 1.9e-10 40.4 0.0 2.2 2 0 0 2 2 1 1 AAA+ lid domain RuvB_N PF05496.12 RLN96351.1 - 3.1e-09 36.8 0.0 5.8e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RLN96351.1 - 2.2e-05 24.6 1.8 0.0002 21.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 RLN96351.1 - 4.6e-05 23.4 0.1 0.00047 20.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RLN96351.1 - 4.6e-05 23.7 0.1 0.13 12.5 0.0 2.8 1 1 1 2 2 2 2 AAA domain Nucleolin_bd PF16725.5 RLN96351.1 - 0.00016 21.2 0.1 0.00046 19.8 0.1 1.7 1 0 0 1 1 1 1 Nucleolin binding domain TIP49 PF06068.13 RLN96351.1 - 0.00058 19.2 0.0 0.00099 18.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 RLN96351.1 - 0.00097 19.3 0.0 0.0068 16.5 0.0 2.4 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 RLN96351.1 - 0.0017 18.7 7.6 0.0019 18.6 0.4 3.6 3 1 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.6 RLN96351.1 - 0.002 17.7 3.0 0.31 10.6 0.1 3.0 2 1 1 3 3 3 2 AAA domain Mg_chelatase PF01078.21 RLN96351.1 - 0.0046 16.4 0.2 0.013 14.8 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 RLN96351.1 - 0.0051 16.6 0.1 0.014 15.2 0.0 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 RLN96351.1 - 0.007 16.3 0.3 0.075 12.9 0.0 2.7 2 1 1 3 3 3 1 NACHT domain RNA_helicase PF00910.22 RLN96351.1 - 0.0099 16.3 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Vps4_C PF09336.10 RLN96351.1 - 0.011 15.7 0.7 0.041 13.9 0.1 2.2 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain ABC_tran PF00005.27 RLN96351.1 - 0.027 15.0 0.4 0.22 12.0 0.0 2.3 2 1 1 3 3 3 0 ABC transporter AAA_18 PF13238.6 RLN96351.1 - 0.058 13.9 0.1 0.25 11.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 RLN96351.1 - 0.07 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RLN96351.1 - 0.089 13.0 1.0 0.23 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 RLN96351.1 - 0.091 11.9 0.0 0.27 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) CPT PF07931.12 RLN96351.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DDE_Tnp_IS66 PF03050.14 RLN96351.1 - 0.12 11.9 2.3 0.2 11.1 2.3 1.3 1 0 0 1 1 1 0 Transposase IS66 family Sigma54_activat PF00158.26 RLN96351.1 - 0.12 12.1 0.0 0.45 10.2 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 RLN96351.1 - 0.2 10.7 0.1 0.78 8.8 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Hydin_ADK PF17213.3 RLN96351.1 - 0.23 11.7 9.5 1.3 9.2 0.0 3.3 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Aldo_ket_red PF00248.21 RLN96352.1 - 2.1e-68 230.7 0.0 2.5e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cation_efflux PF01545.21 RLN96353.1 - 1.9e-47 161.6 0.5 1.9e-47 161.6 0.5 1.4 2 0 0 2 2 2 1 Cation efflux family Zip PF02535.22 RLN96353.1 - 0.047 12.9 14.6 0.057 12.6 13.1 1.8 1 1 0 1 1 1 0 ZIP Zinc transporter Ctr PF04145.15 RLN96353.1 - 0.16 12.6 0.0 1.3 9.6 0.0 2.4 2 0 0 2 2 2 0 Ctr copper transporter family Chorion_3 PF05387.11 RLN96353.1 - 0.18 11.4 1.3 0.27 10.9 1.3 1.2 1 0 0 1 1 1 0 Chorion family 3 Palm_thioest PF02089.15 RLN96354.1 - 7.6e-41 140.5 0.0 1.3e-40 139.7 0.0 1.4 1 1 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 RLN96354.1 - 0.0023 17.5 0.1 0.0064 16.0 0.1 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_2 PF01674.18 RLN96354.1 - 0.0028 17.2 0.0 0.0094 15.5 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 2) PGAP1 PF07819.13 RLN96354.1 - 0.0099 15.6 0.7 0.19 11.4 0.7 2.1 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 RLN96354.1 - 0.011 16.3 0.1 0.016 15.8 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN96354.1 - 0.016 14.9 0.1 0.035 13.7 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 RLN96354.1 - 0.043 13.4 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Cyclin_N PF00134.23 RLN96355.1 - 5.6e-07 29.4 1.4 8.6e-07 28.7 1.4 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain RCC1 PF00415.18 RLN96356.1 - 3.2e-51 171.7 18.7 2.3e-11 44.1 0.0 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN96356.1 - 3.9e-22 77.5 30.7 8.7e-05 22.2 2.9 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat CybS PF05328.12 RLN96357.1 - 7.9e-15 54.7 0.1 1.1e-14 54.2 0.1 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit FYVE PF01363.21 RLN96358.1 - 0.0028 17.8 8.0 0.0058 16.7 8.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger Thioredoxin PF00085.20 RLN96359.1 - 4.4e-62 206.5 2.0 1.6e-30 105.2 0.0 3.6 3 1 1 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 RLN96359.1 - 1.5e-30 106.5 1.4 1.6e-20 73.8 0.1 3.8 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 RLN96359.1 - 1.2e-14 54.6 2.0 0.00015 22.2 0.0 4.3 3 2 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 RLN96359.1 - 2.4e-09 37.2 0.1 0.0047 17.1 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 RLN96359.1 - 3.7e-07 30.1 0.1 0.014 15.3 0.0 3.1 2 1 0 2 2 2 2 AhpC/TSA family OST3_OST6 PF04756.13 RLN96359.1 - 1.4e-06 27.9 0.0 0.053 12.9 0.0 2.6 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 RLN96359.1 - 3.3e-06 27.3 0.0 0.032 14.6 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like Redoxin PF08534.10 RLN96359.1 - 0.0019 18.0 0.6 0.85 9.3 0.0 3.0 3 0 0 3 3 3 2 Redoxin NRIP1_repr_1 PF15687.5 RLN96359.1 - 0.1 12.3 1.9 0.19 11.4 1.9 1.3 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 1 MaoC_dehydratas PF01575.19 RLN96360.1 - 4e-14 52.2 0.1 5.1e-14 51.9 0.1 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 RLN96360.1 - 0.0027 17.9 0.0 0.0053 16.9 0.0 1.5 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 RLN96360.1 - 0.038 14.4 0.5 0.08 13.3 0.5 1.6 1 0 0 1 1 1 0 Thioesterase superfamily zf-CCCH PF00642.24 RLN96361.1 - 2.9e-11 43.0 16.1 9.5e-06 25.4 5.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RLN96361.1 - 0.00016 21.6 13.7 0.00084 19.3 3.3 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 RLN96361.1 - 0.0033 17.2 5.2 0.0033 17.2 5.2 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger XRCC4 PF06632.12 RLN96362.1 - 6.2e-07 28.6 8.3 1.3e-06 27.5 8.3 1.5 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 PKcGMP_CC PF16808.5 RLN96362.1 - 1.2 9.1 9.7 0.56 10.1 3.8 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase C2 PF00168.30 RLN96364.1 - 5e-88 290.1 0.6 4.8e-18 65.3 0.0 8.5 8 0 0 8 8 8 8 C2 domain FerI PF08151.12 RLN96364.1 - 0.00079 19.5 0.4 0.00079 19.5 0.4 3.1 3 0 0 3 3 3 1 FerI (NUC094) domain NT-C2 PF10358.9 RLN96364.1 - 0.0028 17.4 0.4 0.03 14.0 0.0 2.6 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins U3_snoRNA_assoc PF08297.11 RLN96364.1 - 0.069 13.9 2.7 1.3 9.8 1.4 3.0 3 0 0 3 3 3 0 U3 snoRNA associated Abhydrolase_6 PF12697.7 RLN96365.1 - 0.00019 22.1 8.7 0.00019 22.1 8.7 1.8 1 1 0 2 2 2 1 Alpha/beta hydrolase family TauE PF01925.19 RLN96365.1 - 0.0035 17.0 3.2 0.25 11.0 0.2 2.2 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE PAP2 PF01569.21 RLN96365.1 - 0.031 14.1 1.9 0.075 12.8 1.9 1.6 1 0 0 1 1 1 0 PAP2 superfamily Thioesterase PF00975.20 RLN96365.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain Palm_thioest PF02089.15 RLN96365.1 - 0.14 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF5051 PF16473.5 RLN96365.1 - 0.17 11.8 0.0 0.56 10.2 0.0 1.7 2 0 0 2 2 2 0 3' exoribonuclease, RNase T-like SPC12 PF06645.13 RLN96365.1 - 0.18 11.9 0.8 0.62 10.2 0.8 1.9 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) ABC_membrane PF00664.23 RLN96366.1 - 9.5e-57 192.7 3.7 1.1e-56 192.5 3.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN96366.1 - 6e-16 59.2 0.0 1e-15 58.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 RLN96366.1 - 0.00093 19.1 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN96366.1 - 0.0052 16.5 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN96366.1 - 0.11 12.9 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 RLN96367.1 - 1.7e-31 109.2 0.0 4.9e-31 107.7 0.0 1.8 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Methyltransf_25 PF13649.6 RLN96367.1 - 3e-05 24.6 0.0 0.00019 22.1 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN96367.1 - 9.4e-05 22.2 0.0 0.00055 19.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MMR_HSR1 PF01926.23 RLN96367.1 - 0.02 14.9 0.0 0.066 13.3 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase Abhydrolase_9_N PF15420.6 RLN96367.1 - 0.18 11.8 5.4 0.47 10.4 3.4 2.5 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus AAA_16 PF13191.6 RLN96367.1 - 0.29 11.5 0.0 0.29 11.5 0.0 3.2 4 0 0 4 4 4 0 AAA ATPase domain AAA_23 PF13476.6 RLN96367.1 - 0.56 10.7 0.0 0.56 10.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain SLX9 PF15341.6 RLN96367.1 - 2.7 8.4 17.6 0.28 11.6 11.3 2.5 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 Carn_acyltransf PF00755.20 RLN96368.1 - 2.8e-16 59.3 0.4 3e-16 59.2 0.4 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase cNMP_binding PF00027.29 RLN96369.1 - 2.1e-11 43.7 0.0 4.2e-06 26.7 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Methyltransf_11 PF08241.12 RLN96370.1 - 1.6e-14 54.3 0.0 2.4e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN96370.1 - 2.8e-12 47.2 0.1 4.9e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN96370.1 - 3.6e-10 39.8 0.0 4.1e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN96370.1 - 8.7e-09 36.0 0.1 1.3e-08 35.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN96370.1 - 0.00012 22.0 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RLN96370.1 - 0.0014 18.0 0.1 0.0022 17.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 RLN96370.1 - 0.0038 16.6 0.1 0.0053 16.1 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NMO PF03060.15 RLN96370.1 - 0.0044 16.4 0.1 0.007 15.8 0.1 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase CMAS PF02353.20 RLN96370.1 - 0.0074 15.6 0.2 0.0087 15.4 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 RLN96370.1 - 0.016 14.7 0.2 0.032 13.8 0.2 1.5 1 1 0 1 1 1 0 Methyltransferase small domain MMS19_C PF12460.8 RLN96371.1 - 1.7e-81 274.5 0.7 1.7e-81 274.5 0.7 3.2 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 RLN96371.1 - 4.4e-81 272.3 9.8 8.7e-81 271.3 1.8 4.1 4 1 1 5 5 5 1 Dos2-interacting transcription regulator of RNA-Pol-II Cnd1 PF12717.7 RLN96371.1 - 0.0059 16.7 0.1 2.3 8.3 0.0 3.9 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 RICTOR_N PF14664.6 RLN96371.1 - 0.0089 15.1 0.2 0.13 11.2 0.2 2.3 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term HEAT PF02985.22 RLN96371.1 - 0.014 15.6 0.1 0.014 15.6 0.1 7.5 8 0 0 8 8 8 0 HEAT repeat HEAT_EZ PF13513.6 RLN96371.1 - 1 10.0 0.0 1 10.0 0.0 8.6 8 2 2 10 10 10 0 HEAT-like repeat Galactosyl_T PF01762.21 RLN96372.1 - 8.8e-28 97.4 0.0 1.3e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase BESS PF02944.20 RLN96372.1 - 0.063 13.1 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 BESS motif Tnp_zf-ribbon_2 PF13842.6 RLN96373.1 - 0.089 13.6 3.1 0.2 12.5 3.1 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DDE_Tnp_1_7 PF13843.6 RLN96374.1 - 0.00056 19.3 0.0 0.00077 18.9 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 DUF2162 PF09930.9 RLN96374.1 - 0.012 15.1 0.1 0.013 15.0 0.1 1.1 1 0 0 1 1 1 0 Predicted transporter (DUF2162) PCI PF01399.27 RLN96376.1 - 0.18 12.3 0.1 0.18 12.3 0.1 3.7 4 0 0 4 4 4 0 PCI domain Atg14 PF10186.9 RLN96376.1 - 1.5 7.8 16.6 3.3 6.7 16.6 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C4H2 PF10146.9 RLN96376.1 - 4.6 7.5 20.0 52 4.1 17.7 2.7 2 0 0 2 2 2 0 Zinc finger-containing protein Borrelia_P83 PF05262.11 RLN96376.1 - 6.1 5.2 20.4 11 4.3 20.4 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1850 PF08905.11 RLN96379.1 - 0.29 11.5 1.1 2.6 8.5 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1850) MULE PF10551.9 RLN96381.1 - 1.4e-07 31.8 5.3 7.2e-06 26.3 4.0 3.1 2 1 0 2 2 2 1 MULE transposase domain DUF5575 PF17738.1 RLN96381.1 - 0.00034 19.8 0.6 0.00083 18.5 0.6 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF5575) LOR PF04525.12 RLN96382.1 - 0.0044 16.6 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 LURP-one-related Trypan_PARP PF05887.11 RLN96383.1 - 0.0071 16.3 4.1 0.013 15.5 4.1 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Pneumo_att_G PF05539.11 RLN96383.1 - 0.12 11.9 10.3 0.13 11.8 10.3 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G GCOM2 PF15328.6 RLN96383.1 - 0.55 10.6 6.4 0.68 10.3 6.4 1.1 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 LOR PF04525.12 RLN96385.1 - 1.7e-06 27.8 0.0 3.4e-06 26.8 0.0 1.5 2 0 0 2 2 2 1 LURP-one-related TPR_14 PF13428.6 RLN96386.1 - 0.25 12.3 10.5 14 6.8 0.1 5.9 6 1 0 6 6 6 0 Tetratricopeptide repeat Methyltransf_31 PF13847.6 RLN96387.1 - 2.8e-07 30.5 0.4 6.8e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN96387.1 - 1.5e-06 28.8 0.6 1.1e-05 26.0 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 RLN96387.1 - 8e-05 22.2 0.0 0.00028 20.4 0.0 1.8 2 1 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 RLN96387.1 - 0.00025 20.4 0.0 0.0005 19.5 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 RLN96387.1 - 0.0036 17.9 0.1 0.018 15.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 RLN96387.1 - 0.053 13.1 0.8 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_23 PF13489.6 RLN96387.1 - 0.12 12.2 0.2 0.45 10.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain APG6_N PF17675.1 RLN96387.1 - 1.1 9.8 24.6 0.47 11.0 11.3 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF3037 PF11236.8 RLN96387.1 - 2.2 8.7 8.2 0.1 13.1 1.6 2.1 3 0 0 3 3 2 0 Protein of unknown function (DUF3037) Atg14 PF10186.9 RLN96387.1 - 3.5 6.6 12.1 5.6 5.9 12.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 RLN96387.1 - 4.5 7.1 12.5 7.6 6.3 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF2383 PF09537.10 RLN96387.1 - 5.3 7.4 8.2 5.2 7.5 0.7 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF2383) Spc7 PF08317.11 RLN96387.1 - 8.1 5.2 14.7 0.088 11.7 1.7 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein zf-Tim10_DDP PF02953.15 RLN96388.1 - 6.7e-16 57.7 0.7 8.7e-16 57.3 0.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PPR_3 PF13812.6 RLN96389.1 - 0.0059 16.6 0.1 0.093 12.8 0.0 2.4 1 1 1 2 2 2 2 Pentatricopeptide repeat domain Lyase_1 PF00206.20 RLN96389.1 - 0.02 14.3 0.2 0.044 13.2 0.2 1.5 1 0 0 1 1 1 0 Lyase MAGI_u1 PF16663.5 RLN96389.1 - 0.27 11.3 0.9 1 9.5 0.2 2.2 2 0 0 2 2 2 0 Unstructured region on MAGI PPR PF01535.20 RLN96389.1 - 0.5 10.7 1.8 64 4.1 0.0 4.0 5 0 0 5 5 5 0 PPR repeat PPR PF01535.20 RLN96390.1 - 0.004 17.3 1.7 46 4.6 0.0 5.8 6 0 0 6 6 6 1 PPR repeat Corazonin PF17308.2 RLN96390.1 - 0.029 14.7 0.2 0.086 13.2 0.2 1.7 1 0 0 1 1 1 0 Pro-corazonin APG17 PF04108.12 RLN96390.1 - 0.051 12.7 0.1 0.051 12.7 0.1 1.5 2 0 0 2 2 2 0 Autophagy protein Apg17 NAP PF00956.18 RLN96391.1 - 1.4e-61 208.1 1.3 1.9e-61 207.6 1.3 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Muted PF14942.6 RLN96391.1 - 0.0019 18.6 3.5 0.004 17.5 2.6 1.9 2 0 0 2 2 2 1 Organelle biogenesis, Muted-like protein Bap31 PF05529.12 RLN96391.1 - 0.22 11.4 0.1 0.36 10.7 0.1 1.2 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region Latrophilin PF02354.16 RLN96391.1 - 0.29 10.1 1.0 0.47 9.5 1.0 1.4 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region Pkinase PF00069.25 RLN96392.1 - 7.3e-57 192.7 0.0 1.1e-56 192.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN96392.1 - 6.6e-29 101.0 0.0 4.3e-28 98.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN96392.1 - 0.0017 17.8 0.0 0.003 16.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN96392.1 - 0.0036 17.2 0.1 0.0069 16.3 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN96392.1 - 0.018 14.4 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RLN96392.1 - 0.22 11.1 0.1 0.39 10.3 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase SPX PF03105.19 RLN96392.1 - 0.45 10.4 6.3 5.2 6.9 0.4 2.3 2 0 0 2 2 2 0 SPX domain NAP PF00956.18 RLN96393.1 - 2.8e-06 26.7 1.3 2.9e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) PTPRCAP PF15713.5 RLN96393.1 - 0.011 16.1 3.1 0.011 16.0 3.1 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CENP-B_dimeris PF09026.10 RLN96393.1 - 0.069 13.5 8.7 0.097 13.1 8.7 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.13 RLN96393.1 - 0.073 13.0 2.0 0.076 12.9 2.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region GEN1_C PF18380.1 RLN96393.1 - 0.077 13.9 1.1 0.1 13.5 1.1 1.1 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain Importin_rep_4 PF18808.1 RLN96393.1 - 0.12 12.7 1.1 0.16 12.3 1.1 1.1 1 0 0 1 1 1 0 Importin repeat YL1 PF05764.13 RLN96393.1 - 0.21 11.7 5.2 0.23 11.6 5.2 1.0 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 RLN96393.1 - 0.4 8.9 2.0 0.39 9.0 2.0 1.0 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 RLN96393.1 - 0.72 10.3 9.8 1.1 9.7 9.8 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 RLN96393.1 - 3.1 7.0 7.4 3.6 6.8 7.4 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 RLN96393.1 - 3.6 5.6 7.4 3.8 5.5 7.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi Pkinase PF00069.25 RLN96395.1 - 1.9e-48 165.1 0.0 2.2e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN96395.1 - 1.3e-33 116.4 0.0 1.5e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN96395.1 - 2.9e-07 30.1 0.0 4.2e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RLN96395.1 - 4.8e-07 28.9 0.0 6.7e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN96395.1 - 0.00088 19.3 0.6 0.89 9.4 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 RLN96395.1 - 0.0035 16.7 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RLN96395.1 - 0.18 11.4 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Tcp11 PF05794.13 RLN96396.1 - 1.5e-61 208.9 0.1 1.5e-61 208.9 0.1 2.0 2 0 0 2 2 2 1 T-complex protein 11 Holin_BhlA PF10960.8 RLN96396.1 - 0.14 12.2 0.1 0.14 12.2 0.1 1.9 2 0 0 2 2 2 0 BhlA holin family Rcd1 PF04078.13 RLN96397.1 - 2.8e-119 397.2 0.2 3.1e-119 397.0 0.2 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Apolipoprotein PF01442.18 RLN96399.1 - 0.1 12.4 4.7 0.12 12.2 0.7 2.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Chlorosome_CsmC PF11098.8 RLN96399.1 - 0.81 9.7 6.2 1.5 8.8 2.0 3.0 2 0 0 2 2 2 0 Chlorosome envelope protein C Cyt_c_ox_IV PF12270.8 RLN96399.1 - 3.4 7.8 5.6 0.83 9.8 0.1 2.6 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV HMG_box PF00505.19 RLN96401.1 - 2.6e-65 216.8 20.2 2.8e-16 59.7 0.6 5.6 5 0 0 5 5 5 5 HMG (high mobility group) box HMG_box_2 PF09011.10 RLN96401.1 - 1.6e-45 153.5 24.8 2.4e-09 37.6 1.8 5.8 5 0 0 5 5 5 5 HMG-box domain HMG_box_5 PF14887.6 RLN96401.1 - 6.3e-08 32.5 18.0 0.011 15.7 0.6 5.8 6 0 0 6 6 6 3 HMG (high mobility group) box 5 Lyase_1 PF00206.20 RLN96401.1 - 0.021 14.3 0.2 0.12 11.7 0.0 2.3 3 0 0 3 3 3 0 Lyase COX4 PF02936.14 RLN96401.1 - 0.063 13.3 14.7 7.9 6.5 0.2 5.3 5 0 0 5 5 5 0 Cytochrome c oxidase subunit IV LPD11 PF18824.1 RLN96401.1 - 0.48 10.6 7.2 0.16 12.1 0.4 3.6 5 0 0 5 5 5 0 Large polyvalent protein-associated domain 11 Peptidase_M61 PF05299.12 RLN96401.1 - 4.8 7.6 14.6 17 5.8 0.1 4.8 5 0 0 5 5 5 0 M61 glycyl aminopeptidase EamA PF00892.20 RLN96402.1 - 1.6e-06 28.3 28.5 0.002 18.3 9.2 2.3 2 0 0 2 2 2 2 EamA-like transporter family bZIP_1 PF00170.21 RLN96404.1 - 0.0011 19.1 14.1 0.0011 19.1 14.1 2.3 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 RLN96404.1 - 0.0023 18.0 11.6 0.0023 18.0 11.6 3.4 3 0 0 3 3 3 1 Basic region leucine zipper Sigma70_r3 PF04539.16 RLN96404.1 - 0.075 13.1 0.1 0.075 13.1 0.1 3.8 4 0 0 4 4 4 0 Sigma-70 region 3 NPV_P10 PF05531.12 RLN96404.1 - 0.14 12.6 1.7 0.42 11.1 1.7 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein UPF0242 PF06785.11 RLN96404.1 - 0.88 9.7 14.5 0.79 9.8 8.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 RLN96404.1 - 1.1 8.6 20.8 3.4 7.0 1.6 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Aa_trans PF01490.18 RLN96405.1 - 8.2e-47 159.8 23.7 1.4e-46 159.0 23.7 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein START PF01852.19 RLN96405.1 - 5e-11 42.4 0.0 8.1e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 START domain Aa_trans PF01490.18 RLN96406.1 - 1.1e-11 44.2 1.6 1.2e-11 44.0 1.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 RLN96406.1 - 3.8e-05 22.9 1.6 4.6e-05 22.6 1.6 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family TMEM135_C_rich PF15982.5 RLN96407.1 - 2.1e-08 34.8 1.4 5e-08 33.6 1.4 1.6 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 Papilloma_E5 PF03025.14 RLN96407.1 - 0.2 11.8 2.9 5.6 7.2 0.8 2.5 2 0 0 2 2 2 0 Papillomavirus E5 Peptidase_M48 PF01435.18 RLN96408.1 - 1.7e-14 54.1 0.0 1.8e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M48 2-Hacid_dh_C PF02826.19 RLN96409.1 - 9.6e-37 126.1 0.0 1.6e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 RLN96409.1 - 5.9e-05 22.7 0.0 0.00037 20.2 0.0 2.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 RLN96409.1 - 0.017 14.9 0.0 0.051 13.4 0.0 1.8 1 0 0 1 1 1 0 ACT domain AlaDh_PNT_C PF01262.21 RLN96409.1 - 0.13 11.6 0.0 0.32 10.3 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3638 PF12340.8 RLN96410.1 - 5.9e-31 107.6 0.3 1e-29 103.5 0.3 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 RLN96410.1 - 5e-15 54.6 0.0 9.6e-15 53.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) NUC130_3NT PF08158.12 RLN96410.1 - 0.011 16.0 0.3 0.048 14.0 0.3 2.2 1 0 0 1 1 1 0 NUC130/3NT domain EF-hand_8 PF13833.6 RLN96410.1 - 0.027 14.3 0.0 0.1 12.5 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 RLN96410.1 - 0.048 13.2 0.0 0.14 11.8 0.0 1.9 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 RLN96410.1 - 0.048 13.2 0.0 0.16 11.5 0.0 1.9 1 0 0 1 1 1 0 EF hand LrgA PF03788.14 RLN96410.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 LrgA family EF-hand_6 PF13405.6 RLN96410.1 - 0.16 12.0 0.0 0.55 10.3 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain EutK_C PF16365.5 RLN96410.1 - 0.2 11.7 0.8 2.7 8.1 0.1 2.8 2 0 0 2 2 2 0 Ethanolamine utilization protein EutK C-terminus zf-RanBP PF00641.18 RLN96410.1 - 3.5 7.0 21.2 4.9 6.6 2.3 3.4 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others KIX_2 PF16987.5 RLN96411.1 - 1.4e-05 25.0 0.0 5.3e-05 23.1 0.0 2.0 1 0 0 1 1 1 1 KIX domain DUF1041 PF06292.17 RLN96411.1 - 0.0049 17.3 0.2 0.012 16.0 0.2 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) EloA-BP1 PF15870.5 RLN96411.1 - 0.039 14.2 0.3 0.31 11.3 0.0 2.4 2 1 0 2 2 2 0 ElonginA binding-protein 1 Lipoprotein_2 PF00921.17 RLN96411.1 - 0.06 12.9 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 Borrelia lipoprotein TEX12 PF15219.6 RLN96411.1 - 0.12 12.7 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 Testis-expressed 12 Lip_A_acyltrans PF03279.13 RLN96412.1 - 3.1e-05 23.3 0.0 5.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase Thioredoxin PF00085.20 RLN96413.1 - 5.6e-62 206.2 0.0 4.5e-31 106.9 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 RLN96413.1 - 2e-10 41.1 1.2 0.00046 20.6 0.2 4.1 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_6 PF13848.6 RLN96413.1 - 2.9e-08 33.8 0.0 0.0014 18.6 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_3 PF13192.6 RLN96413.1 - 8.8e-07 28.9 0.0 0.02 15.0 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin domain AhpC-TSA PF00578.21 RLN96413.1 - 5.9e-06 26.2 0.1 0.024 14.5 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 RLN96413.1 - 7.3e-06 26.2 0.0 0.25 11.7 0.0 3.8 3 2 1 4 4 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 RLN96413.1 - 1.6e-05 25.0 0.0 0.058 13.6 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 RLN96413.1 - 2.4e-05 23.9 0.0 0.095 12.0 0.0 2.5 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 RLN96413.1 - 0.0027 17.5 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_4 PF13462.6 RLN96413.1 - 0.0034 17.6 0.8 12 6.0 0.1 3.5 2 2 2 4 4 4 0 Thioredoxin TraF PF13728.6 RLN96413.1 - 0.015 15.1 0.0 1.2 8.9 0.0 2.8 3 0 0 3 3 3 0 F plasmid transfer operon protein DSBA PF01323.20 RLN96413.1 - 0.023 14.4 2.8 6.3 6.5 0.0 3.5 2 2 2 4 4 4 0 DSBA-like thioredoxin domain Glutaredoxin PF00462.24 RLN96413.1 - 0.063 13.5 2.5 2.2 8.6 0.2 3.1 2 2 0 2 2 2 0 Glutaredoxin DDE_Tnp_1_2 PF13586.6 RLN96413.1 - 0.075 13.4 0.0 10 6.6 0.0 2.7 3 0 0 3 3 3 0 Transposase DDE domain Thioredoxin_5 PF13743.6 RLN96413.1 - 0.091 12.4 0.1 22 4.7 0.0 3.4 2 2 2 4 4 4 0 Thioredoxin FancD2 PF14631.6 RLN96413.1 - 0.79 7.0 1.5 2.4 5.4 0.0 1.9 2 0 0 2 2 2 0 Fanconi anaemia protein FancD2 nuclease FKBP_C PF00254.28 RLN96414.1 - 2e-28 98.6 0.0 4e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 RLN96414.1 - 5.6e-13 49.4 0.0 5.6e-13 49.4 0.0 2.9 2 1 0 2 2 1 1 Nucleoplasmin-like domain TFIIF_alpha PF05793.12 RLN96414.1 - 0.19 10.3 35.6 0.25 9.9 35.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) YL1 PF05764.13 RLN96414.1 - 0.32 11.1 44.3 0.83 9.7 44.4 1.6 1 1 0 1 1 1 0 YL1 nuclear protein DUF572 PF04502.13 RLN96414.1 - 1.3 8.6 25.2 1.7 8.2 25.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hamartin PF04388.12 RLN96414.1 - 1.7 7.2 12.1 2 7.0 12.1 1.1 1 0 0 1 1 1 0 Hamartin protein Neur_chan_memb PF02932.16 RLN96414.1 - 3.2 7.8 6.1 4.6 7.2 6.1 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nop53 PF07767.11 RLN96414.1 - 4.9 6.4 33.5 7.1 5.9 33.5 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) ECM1 PF05782.11 RLN96414.1 - 5.8 5.7 11.8 8 5.3 11.8 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) PI3K_1B_p101 PF10486.9 RLN96414.1 - 6.1 4.5 14.4 7.9 4.1 14.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GREB1 PF15782.5 RLN96414.1 - 8 3.4 15.4 10 3.1 15.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer HORMA PF02301.18 RLN96417.1 - 1.9e-11 44.0 0.0 8e-05 22.3 0.0 2.1 1 1 0 2 2 2 2 HORMA domain TFIIA PF03153.13 RLN96418.1 - 0.48 10.4 10.7 0.66 9.9 10.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3693 PF12472.8 RLN96419.1 - 1.4 8.6 3.4 15 5.3 0.0 2.6 3 0 0 3 3 3 0 Phage related protein SPC25 PF06703.11 RLN96420.1 - 2.4e-18 66.4 0.2 2.1e-08 34.1 0.0 2.0 1 1 1 2 2 2 2 Microsomal signal peptidase 25 kDa subunit (SPC25) E2F_CC-MB PF16421.5 RLN96421.1 - 7.9e-28 96.7 0.0 1e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain DUF812 PF05667.11 RLN96421.1 - 0.078 11.8 0.4 0.1 11.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) UCMA PF17085.5 RLN96421.1 - 1.3 9.0 5.9 0.13 12.3 1.6 1.4 2 0 0 2 2 2 0 Unique cartilage matrix associated protein FPL PF09758.9 RLN96422.1 - 2.7e-41 141.0 0.0 7.4e-41 139.6 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein LRR_4 PF12799.7 RLN96423.1 - 3.8e-09 36.7 0.4 0.00079 19.8 0.2 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN96423.1 - 1.1e-07 31.5 2.4 0.00031 20.5 0.1 3.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 RLN96423.1 - 0.00013 22.0 1.1 3 8.7 0.0 4.6 4 0 0 4 4 4 2 Leucine Rich Repeat NADH_dhqG_C PF09326.11 RLN96423.1 - 0.016 15.9 0.2 0.059 14.1 0.0 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit G, C-terminal LRR_6 PF13516.6 RLN96423.1 - 0.29 11.3 1.3 1.3 9.3 0.0 2.7 3 0 0 3 3 3 0 Leucine Rich repeat Pkinase PF00069.25 RLN96424.1 - 4.9e-60 203.1 0.0 6.2e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN96424.1 - 8.3e-29 100.6 0.0 1.1e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN96424.1 - 1.4e-05 25.1 0.8 4.3e-05 23.6 0.6 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 RLN96424.1 - 0.00016 21.3 0.0 0.099 12.3 0.0 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 RLN96424.1 - 0.0002 20.8 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 RLN96424.1 - 0.0071 16.0 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 RLN96424.1 - 0.0079 15.6 0.3 0.014 14.7 0.3 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RLN96424.1 - 0.025 13.5 0.1 0.035 13.0 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain CBP_BcsQ PF06564.12 RLN96424.1 - 0.031 13.8 0.0 0.082 12.4 0.0 1.6 1 1 1 2 2 2 0 Cellulose biosynthesis protein BcsQ Pkinase_fungal PF17667.1 RLN96424.1 - 0.037 12.8 0.4 0.08 11.7 0.1 1.3 1 1 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 RLN96424.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 RLN96424.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Palm_thioest PF02089.15 RLN96425.1 - 3.4e-46 158.0 0.0 4e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.18 RLN96425.1 - 0.00021 20.9 0.1 0.00054 19.5 0.1 1.7 1 1 0 1 1 1 1 Lipase (class 2) DUF676 PF05057.14 RLN96425.1 - 0.0017 17.9 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 RLN96425.1 - 0.0033 17.1 0.0 0.0057 16.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN96425.1 - 0.028 15.0 0.0 0.034 14.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 RLN96425.1 - 0.042 13.4 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase RL11D PF11088.8 RLN96425.1 - 0.078 13.3 1.2 0.35 11.2 0.1 2.4 2 1 1 3 3 3 0 Glycoprotein encoding membrane proteins RL5A and RL6 Abhydrolase_6 PF12697.7 RLN96426.1 - 8.1e-15 56.0 3.8 1.2e-14 55.4 3.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN96426.1 - 1.5e-09 37.9 0.0 7.2e-07 29.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN96426.1 - 6e-09 35.5 0.0 1.1e-08 34.6 0.0 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 RLN96426.1 - 0.0024 17.8 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) zf-RanBP PF00641.18 RLN96427.1 - 7.1e-05 22.0 6.7 0.00012 21.3 6.7 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Phage_int_SAM_1 PF02899.17 RLN96428.1 - 0.034 14.4 0.0 0.08 13.3 0.0 1.6 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Peptidase_M16_M PF16187.5 RLN96429.1 - 6.8e-77 258.5 0.1 1.5e-76 257.4 0.0 1.7 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 RLN96429.1 - 4e-33 114.5 0.0 1.9e-32 112.3 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 RLN96429.1 - 5.5e-30 104.7 0.0 2.4e-17 63.6 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain DUF2824 PF11039.8 RLN96429.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) zf-RING_2 PF13639.6 RLN96432.1 - 1.7e-09 37.9 11.4 8.5e-09 35.6 5.6 3.4 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 RLN96432.1 - 3.6e-07 30.0 4.5 3.6e-07 30.0 4.5 3.8 4 0 0 4 4 4 1 zinc-RING finger domain zf-rbx1 PF12678.7 RLN96432.1 - 4.9e-07 29.9 2.0 4.9e-07 29.9 2.0 2.9 4 0 0 4 4 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 RLN96432.1 - 1.9e-06 27.5 3.7 1.9e-06 27.5 3.7 2.0 2 0 0 2 2 2 1 RING-like zinc finger TF_Zn_Ribbon PF08271.12 RLN96432.1 - 0.00011 21.7 0.9 0.00011 21.7 0.9 3.4 4 0 0 4 4 3 1 TFIIB zinc-binding zf-C3HC4 PF00097.25 RLN96432.1 - 0.00034 20.4 4.3 0.00034 20.4 4.3 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RLN96432.1 - 0.00037 20.3 14.7 0.0011 18.8 4.0 3.7 4 0 0 4 4 3 1 Prokaryotic RING finger family 4 zf-C2H2_9 PF16293.5 RLN96432.1 - 0.00049 19.9 2.8 0.19 11.6 0.1 3.2 3 0 0 3 3 3 2 C2H2 type zinc-finger (1 copy) zf-ANAPC11 PF12861.7 RLN96432.1 - 0.0007 19.6 2.4 0.0007 19.6 2.4 2.0 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Di19 PF05605.12 RLN96432.1 - 0.00088 19.5 8.0 0.21 11.9 0.1 4.2 4 0 0 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_3 PF13920.6 RLN96432.1 - 0.0014 18.5 5.6 0.0014 18.5 5.6 3.6 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN96432.1 - 0.0023 17.9 5.3 0.0023 17.9 5.3 2.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-C2H2_jaz PF12171.8 RLN96432.1 - 0.0034 17.6 6.3 0.33 11.3 0.0 4.0 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding Zn-C2H2_12 PF18112.1 RLN96432.1 - 0.0034 17.8 6.6 7.5 7.1 0.1 4.2 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C3HC4_2 PF13923.6 RLN96432.1 - 0.017 15.0 5.1 0.017 15.0 5.1 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 RLN96432.1 - 0.02 14.7 6.3 1.8 8.5 0.1 3.9 4 0 0 4 4 4 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 RLN96432.1 - 0.057 13.2 13.6 0.037 13.8 4.9 3.5 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-C2H2_6 PF13912.6 RLN96432.1 - 0.066 13.2 0.1 0.066 13.2 0.1 4.0 6 0 0 6 6 4 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 RLN96432.1 - 0.076 13.9 0.2 0.076 13.9 0.2 5.2 5 0 0 5 5 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 RLN96432.1 - 0.11 13.0 0.1 0.11 13.0 0.1 4.4 5 0 0 5 5 3 0 Zinc finger, C2H2 type zf-C3HC4_4 PF15227.6 RLN96432.1 - 0.12 12.6 11.9 0.038 14.2 4.9 3.2 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 RLN96432.1 - 0.14 11.8 8.5 0.025 14.2 2.1 2.9 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type zf-HC5HC2H_2 PF13832.6 RLN96432.1 - 0.21 11.8 5.2 0.14 12.3 2.2 2.3 2 1 0 2 2 1 0 PHD-zinc-finger like domain Zf_RING PF16744.5 RLN96432.1 - 0.22 11.6 4.6 1.4 9.1 0.1 3.0 2 0 0 2 2 2 0 KIAA1045 RING finger zf-HC5HC2H PF13771.6 RLN96432.1 - 1.4 9.2 8.6 0.097 12.9 1.7 2.6 3 0 0 3 3 2 0 PHD-like zinc-binding domain zf-C2H2_2 PF12756.7 RLN96432.1 - 1.5 9.2 6.6 2.9 8.3 0.2 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) PHD PF00628.29 RLN96432.1 - 6.4 6.8 13.8 0.54 10.2 2.4 3.9 4 0 0 4 4 4 0 PHD-finger zf-DNL PF05180.12 RLN96433.1 - 4.9e-29 100.1 0.1 6.2e-29 99.7 0.1 1.1 1 0 0 1 1 1 1 DNL zinc finger YABBY PF04690.13 RLN96433.1 - 0.084 13.4 0.1 0.093 13.3 0.1 1.2 1 0 0 1 1 1 0 YABBY protein EGF_2 PF07974.13 RLN96434.1 - 7.3e-05 23.1 11.9 0.00016 22.0 11.9 1.6 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.24 RLN96434.1 - 0.031 14.4 6.2 0.071 13.3 6.2 1.6 1 0 0 1 1 1 0 Laminin EGF domain EGF PF00008.27 RLN96434.1 - 0.47 10.8 10.5 1.3 9.4 10.5 1.7 1 0 0 1 1 1 0 EGF-like domain AA_kinase PF00696.28 RLN96435.1 - 2.8e-14 53.3 0.1 4.2e-14 52.7 0.1 1.2 1 0 0 1 1 1 1 Amino acid kinase family Acetyltransf_1 PF00583.25 RLN96435.1 - 1.7e-07 31.5 0.0 3e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RLN96435.1 - 1.4e-05 25.4 0.0 2.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RLN96435.1 - 4.8e-05 23.3 0.0 9.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_9 PF12781.7 RLN96435.1 - 0.04 13.0 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 ATP-binding dynein motor region Keratin_2_head PF16208.5 RLN96436.1 - 5.2 7.2 13.5 6.5 6.9 13.5 1.2 1 0 0 1 1 1 0 Keratin type II head ACOX PF01756.19 RLN96437.1 - 3.3e-51 173.4 0.0 4.8e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 RLN96437.1 - 1.6e-29 103.0 0.0 2.6e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 RLN96437.1 - 1.1e-11 44.8 0.0 3e-11 43.4 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 RLN96437.1 - 0.061 13.5 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.19 RLN96438.1 - 7.9e-53 178.7 0.0 1.6e-52 177.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 RLN96438.1 - 6.2e-33 114.0 0.0 1.3e-32 112.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 RLN96438.1 - 6.4e-12 45.5 0.0 1.5e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 RLN96438.1 - 0.0014 18.9 0.2 0.0035 17.6 0.2 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RLN96438.1 - 0.022 15.4 0.0 0.079 13.6 0.0 1.9 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain DUF818 PF05677.12 RLN96439.1 - 5.2e-08 32.2 0.0 9.9e-08 31.3 0.0 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_1 PF00561.20 RLN96439.1 - 5.7e-08 32.7 0.0 1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN96439.1 - 6e-07 30.3 0.1 6e-07 30.3 0.1 4.0 3 1 0 3 3 3 1 Alpha/beta hydrolase family Glyco_transf_41 PF13844.6 RLN96439.1 - 8e-06 24.6 0.0 0.027 12.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 41 Hydrolase_4 PF12146.8 RLN96439.1 - 2.5e-05 23.7 0.0 5.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PA PF02225.22 RLN96439.1 - 4.7e-05 23.3 0.0 0.00015 21.7 0.0 1.9 1 0 0 1 1 1 1 PA domain Say1_Mug180 PF10340.9 RLN96439.1 - 0.018 13.9 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase TPR_12 PF13424.6 RLN96440.1 - 1.8e-13 50.5 34.1 9.6e-08 32.2 1.1 8.2 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 RLN96440.1 - 7.9e-12 44.5 13.5 0.019 14.8 0.0 7.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_4 PF07721.14 RLN96440.1 - 4.5e-11 42.3 17.3 0.24 12.1 0.0 8.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 RLN96440.1 - 1.1e-09 37.8 29.6 0.0012 18.6 0.1 8.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 RLN96440.1 - 7.7e-08 31.9 25.8 0.04 14.0 0.1 8.5 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 RLN96440.1 - 2.3e-05 24.9 1.5 2.3e-05 24.9 1.5 7.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 RLN96440.1 - 7.1e-05 22.3 20.4 0.031 13.6 0.5 4.5 6 0 0 6 6 6 3 MalT-like TPR region TPR_7 PF13176.6 RLN96440.1 - 0.00021 21.1 26.8 0.33 11.1 0.1 8.3 9 1 0 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 RLN96440.1 - 0.0036 18.0 32.9 7.8 7.6 0.4 9.8 8 3 0 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN96440.1 - 0.0051 17.0 2.0 0.37 11.1 0.0 3.9 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 RLN96440.1 - 0.04 14.3 9.1 13 6.4 0.1 6.2 5 1 0 5 5 5 0 Tetratricopeptide repeat DUF5112 PF17139.4 RLN96440.1 - 0.047 13.2 3.3 0.78 9.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5112) TPR_19 PF14559.6 RLN96440.1 - 1.4 9.5 17.3 0.79 10.3 0.5 5.6 4 2 2 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN96440.1 - 9 7.2 18.0 40 5.1 0.1 6.8 8 0 0 8 8 6 0 Tetratricopeptide repeat DUF4201 PF13870.6 RLN96441.1 - 5.2e-37 127.3 26.5 5.2e-37 127.3 26.5 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) DUF2937 PF11157.8 RLN96441.1 - 5.1 6.8 6.6 3.8 7.2 0.4 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2937) Kinesin PF00225.23 RLN96443.1 - 2.5e-73 246.9 0.0 2.8e-73 246.8 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN96443.1 - 7e-28 97.4 0.0 1.3e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 RLN96443.1 - 0.088 13.2 0.0 0.13 12.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Bac_DnaA PF00308.18 RLN96443.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein MFS_1 PF07690.16 RLN96444.1 - 3.7e-09 36.0 9.4 3.3e-07 29.6 4.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 RLN96444.1 - 0.015 14.2 4.1 0.027 13.4 0.6 2.1 2 0 0 2 2 2 0 MFS_1 like family MFS_2 PF13347.6 RLN96444.1 - 0.063 11.8 8.1 0.017 13.7 3.6 1.9 2 0 0 2 2 2 0 MFS/sugar transport protein Peptidase_M16 PF00675.20 RLN96445.1 - 1.1e-54 184.5 0.1 1.7e-54 183.8 0.1 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 RLN96445.1 - 3.5e-37 128.2 0.0 6e-36 124.2 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain RbsD_FucU PF05025.13 RLN96445.1 - 0.071 13.5 0.2 0.52 10.7 0.1 2.2 2 0 0 2 2 2 0 RbsD / FucU transport protein family M16C_assoc PF08367.11 RLN96445.1 - 0.089 11.9 0.1 0.2 10.8 0.1 1.6 1 0 0 1 1 1 0 Peptidase M16C associated WW PF00397.26 RLN96446.1 - 7.4e-09 35.5 8.4 0.00018 21.5 0.8 2.3 2 0 0 2 2 2 2 WW domain IQ PF00612.27 RLN96446.1 - 3.8 7.6 13.4 0.61 10.0 2.9 2.9 3 0 0 3 3 3 0 IQ calmodulin-binding motif RTT107_BRCT_5 PF16770.5 RLN96447.1 - 6.1e-08 32.5 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 RLN96447.1 - 8.1e-07 29.3 0.0 3.6e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 RLN96447.1 - 4.4e-06 27.0 0.0 0.057 13.8 0.0 3.0 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 RLN96447.1 - 0.0068 16.7 0.0 0.022 15.0 0.0 1.9 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain SepZ PF06066.11 RLN96447.1 - 0.031 14.5 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 SepZ NIBRIN_BRCT_II PF16508.5 RLN96447.1 - 0.094 13.0 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein GvpG PF05120.12 RLN96449.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Gas vesicle protein G CaM_bdg_C0 PF10562.9 RLN96449.1 - 0.014 15.4 1.2 0.039 14.0 1.2 1.8 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit CDC73_C PF05179.14 RLN96449.1 - 0.031 14.0 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family, C-terminal Amidase PF01425.21 RLN96450.1 - 3.2e-78 263.7 0.6 1.6e-52 179.0 0.5 3.0 1 1 2 3 3 3 3 Amidase Aa_trans PF01490.18 RLN96453.1 - 5.7e-26 91.2 11.2 1.8e-11 43.4 0.0 3.0 3 0 0 3 3 3 3 Transmembrane amino acid transporter protein DUF2427 PF10348.9 RLN96453.1 - 0.84 9.5 6.6 0.44 10.4 0.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) PQ-loop PF04193.14 RLN96454.1 - 2.6e-10 39.9 0.5 3.5e-10 39.5 0.5 1.2 1 0 0 1 1 1 1 PQ loop repeat MtN3_slv PF03083.16 RLN96454.1 - 0.062 13.4 1.0 0.069 13.2 1.0 1.1 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange Retrotran_gag_2 PF14223.6 RLN96455.1 - 3e-10 39.9 0.1 7.9e-10 38.5 0.1 1.7 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 RLN96455.1 - 0.0066 16.5 3.0 0.0066 16.5 3.0 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 RLN96455.1 - 0.014 15.3 1.5 0.032 14.2 1.5 1.6 1 0 0 1 1 1 0 Zinc knuckle DDE_1 PF03184.19 RLN96456.1 - 2.9e-13 49.9 0.0 9.7e-13 48.1 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RLN96456.1 - 1e-06 28.7 0.0 3.6e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 RLN96456.1 - 0.0052 16.5 0.0 0.45 10.3 0.0 2.3 1 1 0 1 1 1 1 DDE superfamily endonuclease NOA36 PF06524.12 RLN96457.1 - 2.2 7.5 5.4 3.3 7.0 5.4 1.2 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 RLN96458.1 - 0.015 15.2 0.3 0.015 15.2 0.3 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region EF-hand_7 PF13499.6 RLN96459.1 - 1.2e-09 38.4 0.0 0.28 11.7 0.0 6.4 6 0 0 6 6 6 3 EF-hand domain pair GHMP_kinases_C PF08544.13 RLN96459.1 - 0.1 13.0 1.8 5.4 7.5 0.0 3.5 2 0 0 2 2 2 0 GHMP kinases C terminal AMP-binding PF00501.28 RLN96460.1 - 4.3e-96 322.1 0.0 5.6e-96 321.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN96460.1 - 0.0011 19.9 0.2 0.0028 18.6 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RCC1 PF00415.18 RLN96461.1 - 2.7e-76 252.0 11.5 4e-14 53.0 0.1 7.8 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN96461.1 - 7.1e-42 140.4 27.5 1.2e-09 37.7 0.1 8.6 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat FHA PF00498.26 RLN96461.1 - 5.2e-12 45.9 0.7 1.4e-11 44.5 0.7 1.9 1 0 0 1 1 1 1 FHA domain SPRY PF00622.28 RLN96461.1 - 2.4e-08 34.1 0.3 0.00023 21.3 0.1 3.3 3 0 0 3 3 3 2 SPRY domain Yop-YscD_cpl PF16697.5 RLN96461.1 - 1.3e-07 31.8 0.0 4.3e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RCC1 PF00415.18 RLN96463.1 - 5.4e-74 244.7 16.0 3.5e-13 49.9 0.1 7.7 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN96463.1 - 3.7e-34 115.8 32.1 3.6e-06 26.6 0.3 8.0 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat SPRY PF00622.28 RLN96463.1 - 9.1e-24 83.9 0.7 5.2e-23 81.4 0.1 2.6 2 0 0 2 2 2 1 SPRY domain Kelch_4 PF13418.6 RLN96463.1 - 1.1e-23 82.9 18.3 0.00017 21.5 0.1 8.4 9 0 0 9 9 9 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN96463.1 - 6.4e-23 80.3 16.7 3.4e-06 26.9 0.0 7.9 9 0 0 9 9 9 5 Kelch motif Kelch_6 PF13964.6 RLN96463.1 - 1.3e-20 72.9 20.3 3.7e-05 23.9 0.2 9.0 8 1 1 9 9 9 5 Kelch motif Kelch_1 PF01344.25 RLN96463.1 - 4.1e-15 55.1 22.8 6.7e-06 25.6 0.1 6.9 7 0 0 7 7 7 3 Kelch motif Kelch_3 PF13415.6 RLN96463.1 - 7.9e-11 42.0 10.7 0.21 11.9 0.1 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 RLN96463.1 - 3.5e-09 36.3 20.6 0.0038 17.1 0.2 7.7 8 0 0 8 8 8 3 Kelch motif Aminotran_1_2 PF00155.21 RLN96464.1 - 2.4e-37 128.9 0.0 4.9e-22 78.6 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II Cupin_8 PF13621.6 RLN96465.1 - 4.5e-37 128.1 0.1 6.1e-37 127.7 0.1 1.1 1 0 0 1 1 1 1 Cupin-like domain AA_permease_2 PF13520.6 RLN96466.1 - 1e-40 139.9 44.0 1.4e-40 139.4 44.0 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN96466.1 - 9e-31 107.0 40.5 1.3e-30 106.5 40.5 1.2 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 RLN96466.1 - 4.4e-05 22.5 12.1 4.4e-05 22.5 12.1 1.6 2 0 0 2 2 2 1 Spore germination protein Orbi_VP6 PF01516.16 RLN96466.1 - 0.019 14.5 0.8 0.03 13.9 0.8 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 DUF2663 PF10864.8 RLN96466.1 - 0.063 13.7 1.0 0.22 11.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) TMEM72 PF16054.5 RLN96466.1 - 1 9.1 11.1 0.34 10.6 2.9 2.6 2 0 0 2 2 2 0 Transmembrane protein family 72 LprI PF07007.12 RLN96466.1 - 3.9 8.2 12.3 3.2 8.5 8.9 2.5 2 0 0 2 2 2 0 Lysozyme inhibitor LprI TPR_1 PF00515.28 RLN96467.1 - 0.0062 16.3 2.0 21 5.1 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN96467.1 - 0.067 12.9 1.5 8.7 6.1 0.0 3.9 4 0 0 4 4 4 0 TPR repeat TPR_2 PF07719.17 RLN96467.1 - 0.3 11.3 9.5 6 7.2 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN96467.1 - 1.8 9.4 5.1 19 6.2 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SNF2_N PF00176.23 RLN96468.1 - 8.7e-50 169.4 0.1 2.4e-49 167.9 0.0 1.8 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN96468.1 - 5.9e-15 55.6 0.0 1.1e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN96468.1 - 1e-08 35.4 0.0 4.8e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RLN96468.1 - 2.1e-07 30.9 0.0 8.6e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Tfb4 PF03850.14 RLN96469.1 - 2.4e-78 263.4 0.0 3.3e-78 263.0 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb4 Trp_syntA PF00290.20 RLN96470.1 - 9e-86 286.9 0.1 1.1e-85 286.7 0.1 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain Kinesin PF00225.23 RLN96471.1 - 2.4e-110 368.6 0.0 2.4e-110 368.6 0.0 3.9 3 2 0 5 5 5 2 Kinesin motor domain Microtub_bd PF16796.5 RLN96471.1 - 8.6e-27 93.9 2.4 9.9e-27 93.7 0.0 2.5 3 0 0 3 3 3 1 Microtubule binding PriA_C PF18074.1 RLN96471.1 - 1.1 10.1 3.1 8.3 7.3 0.5 3.5 2 0 0 2 2 2 0 Primosomal protein N C-terminal domain DEAD PF00270.29 RLN96472.1 - 3.3e-42 144.2 0.1 1.7e-41 141.9 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN96472.1 - 1.1e-28 99.8 0.0 3.6e-28 98.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN96472.1 - 3e-09 37.1 0.0 5.3e-07 29.8 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SDA1 PF05285.12 RLN96472.1 - 6.7e-06 25.8 26.8 6.7e-06 25.8 26.8 1.6 2 0 0 2 2 2 1 SDA1 AAA_22 PF13401.6 RLN96472.1 - 0.0044 17.3 0.8 0.7 10.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain RNase_H2_suC PF08615.11 RLN96472.1 - 0.066 13.4 3.0 2.5 8.3 3.0 2.9 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Apt1 PF10351.9 RLN96472.1 - 0.2 10.5 7.6 0.38 9.5 7.6 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 RLN96472.1 - 8.9 5.0 16.9 0.091 11.5 8.8 1.7 2 0 0 2 2 2 0 Presenilin PPR_2 PF13041.6 RLN96473.1 - 2.8e-48 161.9 0.3 1.4e-07 31.6 0.0 12.5 8 4 4 12 12 12 10 PPR repeat family PPR_3 PF13812.6 RLN96473.1 - 4.1e-29 100.4 0.0 4.3e-06 26.7 0.0 9.8 8 2 6 14 14 14 6 Pentatricopeptide repeat domain PPR PF01535.20 RLN96473.1 - 1.2e-25 87.9 5.9 0.00064 19.8 0.0 12.4 13 0 0 13 13 13 6 PPR repeat PPR_long PF17177.4 RLN96473.1 - 6.1e-23 81.3 2.5 1.3e-08 34.5 0.0 6.4 5 2 2 7 7 7 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 RLN96473.1 - 1.9e-15 56.2 3.6 0.019 14.7 0.0 10.3 11 1 1 12 12 12 4 PPR repeat ATP13 PF12921.7 RLN96473.1 - 8.1e-05 22.5 0.0 0.47 10.3 0.0 4.1 4 1 0 4 4 4 2 Mitochondrial ATPase expression N_NLPC_P60 PF12912.7 RLN96473.1 - 0.015 15.7 0.1 0.057 13.8 0.1 2.0 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term Soc PF16855.5 RLN96473.1 - 0.1 13.1 0.1 0.24 11.9 0.1 1.5 1 0 0 1 1 1 0 Small outer capsid protein CDC45 PF02724.14 RLN96473.1 - 0.44 8.8 11.4 0.75 8.0 3.7 2.3 2 0 0 2 2 2 0 CDC45-like protein Sigma70_ner PF04546.13 RLN96473.1 - 5 6.9 11.4 5.7 6.8 2.1 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region RXT2_N PF08595.11 RLN96473.1 - 9.3 6.3 8.6 8.7 6.4 2.1 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal MFS_1 PF07690.16 RLN96474.1 - 7e-41 140.3 26.8 4.9e-40 137.5 19.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 RLN96474.1 - 0.0016 16.8 3.9 0.2 9.8 0.0 2.2 2 0 0 2 2 2 2 BT1 family Wzy_C PF04932.15 RLN96474.1 - 6.2 6.4 7.7 0.56 9.8 0.2 2.6 2 1 0 2 2 2 0 O-Antigen ligase eIF-5_eIF-2B PF01873.17 RLN96475.1 - 0.052 13.4 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Glyco_hydro_17 PF00332.18 RLN96476.1 - 5.3e-16 59.1 0.6 9.3e-10 38.6 0.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Pribosyltran PF00156.27 RLN96477.1 - 4.7e-07 29.5 0.1 9.5e-07 28.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain LRR_4 PF12799.7 RLN96478.1 - 0.0014 19.0 3.3 0.067 13.6 0.2 3.3 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN96478.1 - 0.12 11.9 0.4 0.18 11.3 0.4 1.2 1 0 0 1 1 1 0 Leucine-rich repeat LRR_8 PF13855.6 RLN96478.1 - 0.18 11.6 1.7 0.56 10.0 0.1 2.5 3 0 0 3 3 3 0 Leucine rich repeat Hemerythrin PF01814.23 RLN96479.1 - 0.066 13.8 0.1 0.35 11.5 0.0 2.0 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain DUF1117 PF06547.12 RLN96480.1 - 0.087 13.4 0.1 2.3 8.8 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1117) DUF3649 PF12365.8 RLN96480.1 - 0.15 11.8 1.7 0.45 10.3 1.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) MRP-L28 PF09812.9 RLN96481.1 - 0.018 15.1 0.1 0.018 15.1 0.1 2.6 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L28 Ank_5 PF13857.6 RLN96482.1 - 1.3e-17 63.6 2.1 3.8e-10 39.8 0.3 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN96482.1 - 1.5e-09 38.3 0.2 5.9e-09 36.4 0.2 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 RLN96482.1 - 9.1e-09 35.4 1.1 1.8e-05 25.0 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat IQ PF00612.27 RLN96482.1 - 9.8e-08 31.2 10.9 0.0081 15.9 0.2 4.8 5 0 0 5 5 5 2 IQ calmodulin-binding motif Ank_4 PF13637.6 RLN96482.1 - 5.7e-07 30.0 0.2 0.00023 21.6 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN96482.1 - 7.1e-07 29.1 0.2 0.00066 19.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat RRP36 PF06102.12 RLN96482.1 - 0.027 14.4 6.4 0.057 13.4 6.4 1.5 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Peptidase_M24 PF00557.24 RLN96483.1 - 1.7e-41 142.2 0.1 2.6e-41 141.6 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 LRR_8 PF13855.6 RLN96483.1 - 4.9e-05 23.0 1.9 0.0014 18.4 0.1 2.3 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RLN96483.1 - 0.026 14.9 2.8 2.1 8.9 2.3 2.4 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) ABC_tran PF00005.27 RLN96484.1 - 2.4e-60 203.0 0.0 2.7e-30 105.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 RLN96484.1 - 8.9e-47 159.9 30.8 8.8e-34 117.1 13.9 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 RLN96484.1 - 1.2e-22 81.2 2.1 1.3e-08 35.1 0.1 4.3 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RLN96484.1 - 2.5e-05 24.9 1.0 0.017 15.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RLN96484.1 - 0.0014 18.9 0.1 0.66 10.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain MukB PF04310.12 RLN96484.1 - 0.0016 18.3 1.3 0.55 10.0 0.2 2.4 2 0 0 2 2 2 2 MukB N-terminal AAA_29 PF13555.6 RLN96484.1 - 0.0019 17.9 3.8 0.017 14.8 0.3 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 RLN96484.1 - 0.003 17.0 0.0 6.8 6.1 0.0 3.4 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 RLN96484.1 - 0.0046 16.9 0.3 0.85 9.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 RLN96484.1 - 0.0067 16.2 0.9 1.3 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF4162 PF13732.6 RLN96484.1 - 0.021 15.6 1.0 1.7 9.4 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4162) AAA_15 PF13175.6 RLN96484.1 - 0.069 12.8 0.0 0.9 9.2 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_16 PF13191.6 RLN96484.1 - 0.086 13.2 0.5 18 5.7 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain Rad17 PF03215.15 RLN96484.1 - 0.1 12.5 0.0 0.9 9.4 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 RLN96484.1 - 0.19 11.3 5.1 6 6.5 0.5 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain HTH_Tnp_Tc5 PF03221.16 RLN96485.1 - 2.6e-14 53.0 0.1 4.4e-14 52.2 0.1 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Cyclin_C_2 PF16899.5 RLN96486.1 - 2.8e-08 34.1 0.2 9e-08 32.5 0.1 2.0 1 1 0 1 1 1 1 Cyclin C-terminal domain Cyclin_N PF00134.23 RLN96486.1 - 1.2e-06 28.3 0.2 2.1e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF885 PF05960.11 RLN96486.1 - 0.014 15.1 1.8 0.023 14.3 1.8 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) cwf18 PF08315.12 RLN96487.1 - 1.5e-18 67.8 12.1 1.5e-18 67.8 12.1 2.1 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor ANAPC15 PF15243.6 RLN96487.1 - 0.013 15.8 6.6 0.013 15.8 6.6 3.2 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 15 Nucleo_P87 PF07267.11 RLN96487.1 - 0.21 10.4 10.1 0.24 10.2 10.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Sugar_tr PF00083.24 RLN96489.1 - 1.5e-68 231.8 20.1 1.5e-68 231.8 20.1 1.7 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RLN96489.1 - 1.2e-21 77.0 25.0 2.3e-21 76.1 24.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Auto_anti-p27 PF06677.12 RLN96490.1 - 0.0012 19.0 0.1 0.0018 18.4 0.1 1.2 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF3_subunit PF08597.10 RLN96490.1 - 0.061 13.2 9.8 0.07 13.0 9.8 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF1501 PF07394.12 RLN96490.1 - 0.063 12.3 5.0 0.069 12.2 5.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) P5-ATPase PF12409.8 RLN96490.1 - 0.14 12.3 0.6 0.16 12.1 0.6 1.1 1 0 0 1 1 1 0 P5-type ATPase cation transporter Hemocyanin_M PF00372.19 RLN96490.1 - 0.15 11.2 0.0 0.19 10.9 0.0 1.0 1 0 0 1 1 1 0 Hemocyanin, copper containing domain Gcd10p PF04189.13 RLN96490.1 - 2.3 7.3 7.1 2.6 7.1 7.1 1.0 1 0 0 1 1 1 0 Gcd10p family DUF2058 PF09831.9 RLN96490.1 - 2.7 8.1 15.8 3.2 7.9 15.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Sec62 PF03839.16 RLN96490.1 - 4.7 6.6 5.6 5.7 6.4 5.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 RNase_H2_suC PF08615.11 RLN96491.1 - 1.6e-11 44.5 0.0 2.3e-11 44.0 0.0 1.3 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF4638 PF15472.6 RLN96492.1 - 0.3 10.8 1.1 0.48 10.1 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Zip PF02535.22 RLN96492.1 - 0.3 10.3 2.7 10 5.2 0.2 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Myc_N PF01056.18 RLN96492.1 - 1 9.2 5.6 2.3 8.1 0.2 2.1 2 0 0 2 2 2 0 Myc amino-terminal region Pro_isomerase PF00160.21 RLN96493.1 - 3.3e-14 53.5 0.0 5.5e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD S10_plectin PF03501.15 RLN96493.1 - 0.08 13.0 0.0 3 8.0 0.0 2.5 3 0 0 3 3 3 0 Plectin/S10 domain AAA PF00004.29 RLN96494.1 - 9.4e-41 139.3 0.0 1.6e-40 138.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RLN96494.1 - 6.3e-13 48.3 0.1 1.3e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 RLN96494.1 - 1.1e-10 41.3 0.1 3.1e-10 39.9 0.1 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 RLN96494.1 - 7e-07 29.8 0.0 0.00054 20.4 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 RLN96494.1 - 2.1e-05 24.7 0.0 4.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 RLN96494.1 - 7e-05 23.1 0.1 0.049 13.9 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 RLN96494.1 - 0.00011 22.3 0.2 0.0012 18.8 0.2 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RLN96494.1 - 0.00014 21.6 0.0 0.00035 20.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 RLN96494.1 - 0.0017 18.7 0.0 0.0041 17.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Prot_ATP_OB_N PF17758.1 RLN96494.1 - 0.0019 17.8 0.3 0.0075 15.9 0.0 2.1 3 0 0 3 3 1 1 Proteasomal ATPase OB N-terminal domain IstB_IS21 PF01695.17 RLN96494.1 - 0.0028 17.4 0.0 0.0059 16.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 RLN96494.1 - 0.0032 16.7 0.0 0.0063 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 RLN96494.1 - 0.0041 16.5 0.0 0.0079 15.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 RLN96494.1 - 0.0055 17.2 0.1 0.023 15.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 RLN96494.1 - 0.0072 15.6 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 RLN96494.1 - 0.01 15.4 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 RLN96494.1 - 0.013 14.8 0.2 0.11 11.8 0.0 2.3 3 0 0 3 3 3 0 KaiC AAA_28 PF13521.6 RLN96494.1 - 0.014 15.7 0.0 0.031 14.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 RLN96494.1 - 0.016 14.7 0.0 0.041 13.4 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 RLN96494.1 - 0.025 14.7 0.0 0.057 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RLN96494.1 - 0.038 13.7 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 RLN96494.1 - 0.039 13.7 0.0 0.12 12.0 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 RLN96494.1 - 0.041 13.3 0.1 0.076 12.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_3 PF07726.11 RLN96494.1 - 0.054 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 RLN96494.1 - 0.071 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 RLN96494.1 - 0.076 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 RLN96494.1 - 0.082 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 RLN96494.1 - 0.14 12.1 0.0 0.37 10.7 0.0 1.8 1 1 1 2 2 2 0 NACHT domain Csm2_III-A PF03750.13 RLN96495.1 - 0.046 14.5 1.4 0.046 14.5 1.4 2.4 2 1 0 2 2 2 0 Csm2 Type III-A Nicastrin PF05450.15 RLN96495.1 - 0.18 11.2 1.8 0.28 10.6 0.1 2.0 2 0 0 2 2 2 0 Nicastrin DUF4404 PF14357.6 RLN96495.1 - 0.21 12.3 18.8 0.088 13.5 4.3 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) NAPRTase_N PF17767.1 RLN96495.1 - 1.1 9.7 5.1 3.8 7.9 1.4 2.3 1 1 1 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF1664 PF07889.12 RLN96495.1 - 2.2 8.3 11.4 0.61 10.1 3.4 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 RLN96495.1 - 8.5 5.8 22.7 0.99 8.9 12.7 2.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit GATase_7 PF13537.6 RLN96497.1 - 1.1e-42 144.9 0.0 6.3e-42 142.4 0.0 2.2 2 1 1 3 3 3 1 Glutamine amidotransferase domain Asn_synthase PF00733.21 RLN96497.1 - 4e-39 135.3 0.0 5.4e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_6 PF13522.6 RLN96497.1 - 1.5e-30 106.1 0.0 2.5e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 RLN96497.1 - 1.5e-12 47.4 0.2 3.6e-12 46.2 0.1 1.6 2 0 0 2 2 2 1 Aluminium induced protein NAD_synthase PF02540.17 RLN96497.1 - 0.036 13.2 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD synthase tRNA_Me_trans PF03054.16 RLN96497.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Cys_Met_Meta_PP PF01053.20 RLN96498.1 - 7.2e-131 436.2 0.0 8.7e-131 436.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 RLN96498.1 - 7.1e-10 38.4 0.0 1.6e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 RLN96498.1 - 3.2e-05 23.4 0.0 7.4e-05 22.2 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.16 RLN96498.1 - 7.8e-05 21.7 0.0 0.00013 21.0 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Aminotran_1_2 PF00155.21 RLN96498.1 - 0.00013 21.3 0.0 0.00022 20.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II p450 PF00067.22 RLN96499.1 - 2.9e-14 52.7 0.0 3.5e-14 52.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 5_nucleotid_C PF02872.18 RLN96501.1 - 3.2e-21 76.2 0.0 5.6e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 RLN96501.1 - 1.7e-08 35.3 0.1 2.7e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FAD_binding_3 PF01494.19 RLN96503.1 - 1.4e-16 60.7 1.0 4.1e-14 52.6 1.0 3.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 RLN96503.1 - 1.2e-05 25.5 0.0 3.9e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RLN96503.1 - 1.7e-05 24.6 0.0 5.4e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RLN96503.1 - 0.00061 19.1 0.1 0.0034 16.6 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RLN96503.1 - 0.0049 17.4 0.0 0.021 15.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RLN96503.1 - 0.0053 15.9 0.0 1.1 8.3 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein ApbA PF02558.16 RLN96503.1 - 0.017 14.8 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 RLN96503.1 - 0.02 14.0 0.0 0.042 12.9 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 RLN96503.1 - 0.061 12.6 0.2 0.87 8.8 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RLN96503.1 - 0.078 11.7 0.1 0.53 8.9 0.1 2.0 1 1 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 RLN96503.1 - 0.18 12.0 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain CBM9_1 PF06452.11 RLN96504.1 - 1.2e-05 25.3 0.0 2.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate family 9 binding domain-like CBM9_2 PF16011.5 RLN96504.1 - 0.029 14.1 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate-binding family 9 Pilin_GH PF16734.5 RLN96504.1 - 0.04 14.2 0.0 0.28 11.5 0.0 2.3 2 0 0 2 2 2 0 Type IV pilin-like G and H, putative DUF5090 PF17009.5 RLN96505.1 - 0.16 11.9 1.6 0.33 10.9 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Ninjurin PF04923.12 RLN96505.1 - 3.6 7.6 9.1 0.64 10.0 0.5 3.1 2 1 0 2 2 2 0 Ninjurin Peptidase_S8 PF00082.22 RLN96506.1 - 8e-31 107.4 0.1 1e-30 107.1 0.1 1.1 1 0 0 1 1 1 1 Subtilase family GDP_Man_Dehyd PF16363.5 RLN96507.1 - 1.4e-72 244.9 0.0 2.8e-65 220.9 0.0 2.0 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RLN96507.1 - 6.8e-55 186.2 0.0 2.7e-54 184.2 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 RLN96507.1 - 1.8e-20 73.2 0.0 6.1e-16 58.4 0.0 3.1 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 RLN96507.1 - 2e-17 63.1 0.0 7.6e-13 48.1 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 RLN96507.1 - 4.3e-17 62.1 0.0 1.4e-13 50.7 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 RLN96507.1 - 1.5e-16 60.4 0.0 5.8e-15 55.1 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 RLN96507.1 - 0.0095 15.8 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding Myb_DNA-binding PF00249.31 RLN96508.1 - 1.2e-09 38.2 0.1 2e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Peptidase_M14 PF00246.24 RLN96509.1 - 2.6e-43 148.9 0.0 3.9e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF1180 PF06679.12 RLN96509.1 - 0.029 14.8 0.3 0.089 13.2 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Glyco_hydro_16 PF00722.21 RLN96509.1 - 0.041 13.3 0.0 0.13 11.7 0.0 1.8 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 CARDB PF07705.11 RLN96509.1 - 0.085 13.1 1.0 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 CARDB Gram_pos_anchor PF00746.21 RLN96509.1 - 1.7 8.7 3.4 3.6 7.6 3.4 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Ank_2 PF12796.7 RLN96510.1 - 1.3e-39 134.7 30.1 8.6e-09 35.9 0.1 6.4 1 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN96510.1 - 1.1e-31 108.8 24.6 5e-06 27.0 0.1 10.5 8 3 2 11 11 11 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN96510.1 - 1.3e-31 108.2 32.6 0.0051 17.1 0.1 15.5 4 2 12 16 16 16 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN96510.1 - 3.6e-19 66.8 18.4 1.2 9.9 0.0 13.9 13 2 2 15 15 15 5 Ankyrin repeat Ank PF00023.30 RLN96510.1 - 9e-08 32.2 5.3 23 5.6 0.0 10.4 4 3 2 6 6 6 0 Ankyrin repeat DUF5049 PF16468.5 RLN96510.1 - 9.7e-05 22.2 0.0 11 6.0 0.0 6.6 5 1 2 7 7 7 1 Domain of unknown function (DUF5049) Zmiz1_N PF18028.1 RLN96510.1 - 0.015 15.6 0.1 0.39 11.0 0.0 3.1 2 0 0 2 2 2 0 Zmiz1 N-terminal tetratricopeptide repeat domain DUF249 PF03158.13 RLN96510.1 - 0.039 13.6 4.8 18 4.9 0.1 4.9 3 2 0 4 4 4 0 Multigene family 530 protein DUF1987 PF09345.10 RLN96510.1 - 0.97 9.1 4.9 12 5.5 0.0 4.7 5 2 1 6 6 6 0 Domain of unknown function (DUF1987) UPF0489 PF12640.7 RLN96510.1 - 1.2 9.3 7.6 27 4.9 0.2 5.2 1 1 4 5 5 5 0 UPF0489 domain Bin3 PF06859.12 RLN96510.1 - 7.7 7.2 5.2 42 4.8 0.0 4.2 5 0 0 5 5 5 0 Bicoid-interacting protein 3 (Bin3) UPF0184 PF03670.13 RLN96511.1 - 0.025 15.0 1.7 0.025 15.0 1.7 3.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) Pox_A_type_inc PF04508.12 RLN96511.1 - 0.25 11.2 11.8 0.78 9.7 0.2 5.4 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat bZIP_2 PF07716.15 RLN96512.1 - 0.0088 16.1 11.1 0.0088 16.1 11.1 2.4 1 1 1 2 2 2 1 Basic region leucine zipper PG_binding_1 PF01471.18 RLN96512.1 - 0.13 12.5 1.2 1.1 9.5 0.7 2.4 2 0 0 2 2 2 0 Putative peptidoglycan binding domain AA_permease_2 PF13520.6 RLN96513.1 - 3.1e-24 85.6 25.4 4e-24 85.2 25.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN96513.1 - 1.1e-14 53.9 21.3 1.8e-14 53.2 21.3 1.3 1 0 0 1 1 1 1 Amino acid permease O-antigen_lig PF13425.6 RLN96513.1 - 4.7 5.9 5.5 0.48 9.2 0.9 1.6 2 0 0 2 2 2 0 O-antigen ligase like membrane protein AA_permease_2 PF13520.6 RLN96514.1 - 3.7e-26 91.9 22.5 4.8e-26 91.6 22.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN96514.1 - 4.3e-22 78.4 15.0 4.3e-22 78.4 15.0 1.3 1 1 0 1 1 1 1 Amino acid permease DUF2568 PF10823.8 RLN96514.1 - 0.074 13.3 0.5 0.074 13.3 0.5 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF2568) Dimer_Tnp_hAT PF05699.14 RLN96515.1 - 5.1e-08 32.6 0.0 9.4e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Bombinin PF05298.11 RLN96515.1 - 0.071 12.8 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Bombinin Focal_AT PF03623.13 RLN96515.1 - 0.11 12.5 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Focal adhesion targeting region PROCN PF08083.11 RLN96516.1 - 0.0087 14.8 2.5 0.013 14.3 2.5 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain FapA PF03961.13 RLN96516.1 - 0.0094 14.6 8.6 0.0062 15.2 7.2 1.3 1 1 0 1 1 1 1 Flagellar Assembly Protein A GAF PF01590.26 RLN96517.1 - 0.037 14.7 0.0 0.048 14.3 0.0 1.4 1 1 0 1 1 1 0 GAF domain DUF2817 PF10994.8 RLN96519.1 - 1.4e-13 51.0 0.0 2e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) IlvN PF07991.12 RLN96520.1 - 1.8e-06 27.7 0.1 2.9e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain OrfB_Zn_ribbon PF07282.11 RLN96521.1 - 1.7e-07 31.0 1.5 8.3e-07 28.9 1.5 2.2 1 1 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 RLN96521.1 - 0.048 13.9 0.2 0.15 12.3 0.2 1.8 1 0 0 1 1 1 0 Probable transposase TMP-TENI PF02581.17 RLN96521.1 - 0.14 11.5 0.1 0.33 10.3 0.1 1.6 1 0 0 1 1 1 0 Thiamine monophosphate synthase IlvC PF01450.19 RLN96522.1 - 2.5e-44 151.1 0.0 4.1e-33 114.7 0.0 2.2 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.12 RLN96522.1 - 1.3e-21 76.9 0.0 2.2e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain RabGAP-TBC PF00566.18 RLN96523.1 - 6.5e-16 58.6 0.0 8e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF2817 PF10994.8 RLN96524.1 - 5.7e-68 229.8 0.0 6.7e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) zf-rbx1 PF12678.7 RLN96525.1 - 4e-06 27.0 1.2 8.7e-06 25.9 1.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 RLN96525.1 - 8.1e-06 26.1 1.8 8.1e-06 26.1 1.8 1.7 2 0 0 2 2 2 1 Ring finger domain RINGv PF12906.7 RLN96525.1 - 0.00043 20.3 1.6 0.00043 20.3 1.6 2.0 2 0 0 2 2 2 1 RING-variant domain zf-ANAPC11 PF12861.7 RLN96525.1 - 0.0042 17.1 0.2 0.0077 16.3 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 RLN96525.1 - 0.024 14.5 2.7 0.054 13.3 2.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN96525.1 - 0.11 12.4 1.5 0.25 11.2 1.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 RLN96525.1 - 1.4 9.1 4.9 10 6.4 4.9 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain E1-E2_ATPase PF00122.20 RLN96526.1 - 1.3e-23 83.5 0.1 1.3e-23 83.5 0.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 RLN96526.1 - 2.8e-16 60.4 0.1 7.8e-08 32.9 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN96526.1 - 1.7e-05 24.8 0.0 4.3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 RLN96526.1 - 0.0011 18.8 0.0 0.65 9.7 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase GAGBD PF16828.5 RLN96527.1 - 0.021 14.9 0.4 0.052 13.6 0.4 1.6 1 0 0 1 1 1 0 GAG-binding domain on surface antigen TPR_12 PF13424.6 RLN96528.1 - 8.2e-36 122.2 15.9 1.3e-14 54.2 4.8 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 RLN96528.1 - 6.7e-34 114.8 19.2 3.9e-09 36.1 0.6 6.6 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 RLN96528.1 - 2.6e-14 52.3 23.6 0.00035 20.2 0.2 6.6 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 RLN96528.1 - 6.6e-13 47.8 17.5 0.0017 18.4 0.1 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 RLN96528.1 - 2e-11 43.1 14.5 0.0014 18.6 0.2 6.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN96528.1 - 3.3e-11 42.4 25.1 0.07 13.3 0.1 6.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 RLN96528.1 - 3.8e-08 33.4 11.4 0.61 10.9 0.1 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 RLN96528.1 - 4.3e-07 29.6 5.9 2.2e-05 24.0 3.5 2.4 1 1 1 2 2 2 2 MalT-like TPR region DUF2225 PF09986.9 RLN96528.1 - 7.6e-07 29.1 4.5 0.00096 18.9 0.3 2.2 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_19 PF14559.6 RLN96528.1 - 6.9e-06 26.5 11.2 0.00032 21.2 1.4 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN96528.1 - 1.3e-05 25.6 20.3 2.9 8.9 0.1 6.9 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN96528.1 - 2.4e-05 24.4 5.4 3.1 8.4 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN96528.1 - 0.00042 20.9 12.6 0.34 11.6 0.0 5.1 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN96528.1 - 0.00057 19.5 14.5 0.17 11.6 0.2 5.5 5 1 1 6 6 6 2 TPR repeat SNAP PF14938.6 RLN96528.1 - 0.00085 18.8 12.2 0.005 16.3 1.5 3.0 1 1 2 3 3 3 2 Soluble NSF attachment protein, SNAP MIT PF04212.18 RLN96528.1 - 0.019 15.0 12.7 0.31 11.1 3.1 4.0 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain 14-3-3 PF00244.20 RLN96528.1 - 0.082 12.4 4.5 0.25 10.8 0.1 2.9 1 1 1 3 3 3 0 14-3-3 protein RPN6_N PF18055.1 RLN96528.1 - 0.083 13.3 4.1 0.61 10.5 1.0 2.9 1 1 2 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain DUF4404 PF14357.6 RLN96528.1 - 0.094 13.4 0.1 2.9 8.6 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) ANAPC5 PF12862.7 RLN96528.1 - 0.11 12.6 1.3 4 7.6 0.1 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_4 PF07721.14 RLN96528.1 - 0.38 11.5 6.5 0.73 10.6 0.0 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat Remorin_C PF03763.13 RLN96528.1 - 1.1 9.2 4.9 0.63 9.9 2.1 2.1 2 1 0 2 2 2 0 Remorin, C-terminal region Crystall_3 PF08964.10 RLN96530.1 - 0.079 13.1 0.6 1 9.6 0.0 2.2 2 0 0 2 2 2 0 Beta/Gamma crystallin Pab87_oct PF13969.6 RLN96532.1 - 0.16 12.1 0.0 0.37 10.9 0.0 1.6 1 1 0 1 1 1 0 Pab87 octamerisation domain PsaF PF17550.2 RLN96533.1 - 0.032 13.8 0.1 0.092 12.2 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function GP17 PF17420.2 RLN96535.1 - 0.028 14.6 0.1 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 Superinfection exclusion gene product 17 LT-IIB PF06453.11 RLN96535.1 - 0.055 13.4 0.8 0.73 9.7 0.0 2.7 3 0 0 3 3 3 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) DUF1374 PF07118.11 RLN96535.1 - 0.077 13.5 0.7 6.8 7.3 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1374) Abhydrolase_6 PF12697.7 RLN96536.1 - 1e-08 36.1 0.0 1.7e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family YojJ PF10372.9 RLN96536.1 - 0.051 13.7 0.1 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus SAPIS-gp6 PF16722.5 RLN96536.1 - 0.056 13.9 0.8 1.4 9.4 0.1 2.3 1 1 1 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus DUF1057 PF06342.12 RLN96536.1 - 0.12 11.4 0.2 0.34 9.9 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Ammonium_transp PF00909.21 RLN96537.1 - 9.4e-113 376.9 29.8 1.2e-112 376.5 29.8 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Proton_antipo_N PF00662.20 RLN96537.1 - 2.4 8.3 10.3 0.44 10.7 1.6 2.9 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Ammonium_transp PF00909.21 RLN96538.1 - 7.6e-116 387.1 34.3 9.4e-116 386.8 34.3 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Cytomega_TRL10 PF06084.11 RLN96538.1 - 0.063 13.3 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein CCDC53 PF10152.9 RLN96539.1 - 2.1e-08 34.7 27.4 1.4e-06 28.8 27.1 3.5 1 1 0 1 1 1 1 Subunit CCDC53 of WASH complex YebG PF07130.12 RLN96539.1 - 0.085 12.7 2.1 0.2 11.5 0.0 2.7 3 0 0 3 3 3 0 YebG protein SYCE1 PF15233.6 RLN96542.1 - 0.33 11.0 2.2 0.75 9.8 2.2 1.5 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 HECT PF00632.25 RLN96543.1 - 1.4e-92 310.4 0.0 1.9e-92 310.0 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HTH_Tnp_Tc5 PF03221.16 RLN96545.1 - 3.9e-07 30.0 0.0 7.2e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 RLN96545.1 - 0.043 13.6 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF2461 PF09365.10 RLN96546.1 - 0.046 13.7 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) PH PF00169.29 RLN96546.1 - 0.074 13.6 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 PH domain Ion_trans PF00520.31 RLN96547.1 - 1.4e-18 67.0 13.8 2.3e-18 66.3 13.8 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RLN96547.1 - 2.9e-15 56.0 5.0 2.9e-15 56.0 5.0 3.7 4 0 0 4 4 4 1 Ion channel PKD_channel PF08016.12 RLN96547.1 - 1.7e-05 23.7 3.0 3e-05 22.9 3.0 1.3 1 0 0 1 1 1 1 Polycystin cation channel DZR PF12773.7 RLN96547.1 - 0.00041 20.3 0.3 0.00069 19.6 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 RLN96547.1 - 0.0061 16.2 1.1 0.012 15.3 1.1 1.5 1 0 0 1 1 1 1 zinc-ribbon domain NOB1_Zn_bind PF08772.11 RLN96547.1 - 0.065 13.4 0.3 0.11 12.7 0.3 1.4 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like CAAD PF14159.6 RLN96547.1 - 0.067 13.0 2.5 0.12 12.2 0.3 2.3 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase zf-ribbon_3 PF13248.6 RLN96547.1 - 0.067 12.6 0.2 0.14 11.6 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Lig_chan PF00060.26 RLN96547.1 - 0.11 12.4 0.9 13 5.7 0.2 2.5 2 0 0 2 2 2 0 Ligand-gated ion channel Prok-RING_1 PF14446.6 RLN96547.1 - 0.15 12.0 0.5 0.3 11.1 0.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF2434 PF10361.9 RLN96547.1 - 1.4 7.9 6.0 1.3 8.0 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2434) GPI-anchored PF10342.9 RLN96548.1 - 0.0015 19.2 0.4 0.0031 18.2 0.0 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AFG1_ATPase PF03969.16 RLN96551.1 - 9.1e-96 320.9 0.0 1.2e-95 320.5 0.0 1.1 1 0 0 1 1 1 1 AFG1-like ATPase AAA_16 PF13191.6 RLN96551.1 - 0.0022 18.4 0.5 0.25 11.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 RLN96551.1 - 0.0066 16.5 0.0 0.025 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 RLN96551.1 - 0.042 13.7 0.0 0.13 12.1 0.0 1.8 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_19 PF13245.6 RLN96551.1 - 0.043 14.2 0.1 12 6.3 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 RLN96551.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain RXLR PF16810.5 RLN96552.1 - 0.041 14.3 1.5 0.052 14.0 1.5 1.2 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity MIT PF04212.18 RLN96552.1 - 0.046 13.8 0.1 0.089 12.9 0.1 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Alpha-E PF04168.12 RLN96552.1 - 0.064 13.0 0.2 0.11 12.3 0.1 1.4 1 1 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. HR1 PF02185.16 RLN96553.1 - 0.0055 16.8 3.7 0.016 15.3 3.7 1.8 1 1 0 1 1 1 1 Hr1 repeat RXLR PF16810.5 RLN96553.1 - 0.019 15.4 1.0 0.02 15.3 1.0 1.1 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity DUF2277 PF10041.9 RLN96553.1 - 0.043 14.1 0.4 0.059 13.7 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) NAPRTase_N PF17767.1 RLN96555.1 - 9.9e-32 110.0 0.0 2.5e-31 108.6 0.0 1.6 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase PF04095.16 RLN96555.1 - 0.0081 15.8 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF3234 PF11572.8 RLN96555.1 - 0.08 13.1 0.0 0.52 10.5 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3234) QRPTase_N PF02749.16 RLN96555.1 - 0.16 12.0 0.0 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain LRR_4 PF12799.7 RLN96556.1 - 2.6e-46 154.8 29.3 7.5e-10 38.9 0.9 6.3 1 1 7 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN96556.1 - 1.2e-32 111.5 39.2 7.3e-08 32.1 4.8 5.2 1 1 5 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 RLN96556.1 - 2.3e-24 85.8 7.8 1.5e-13 50.6 0.2 3.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 RLN96556.1 - 3.8e-09 35.8 10.6 4.6 8.2 0.2 8.4 9 1 0 9 9 9 3 Leucine Rich Repeat LRR_6 PF13516.6 RLN96556.1 - 1.2e-05 25.0 14.9 2.7 8.3 0.1 7.9 9 0 0 9 9 9 3 Leucine Rich repeat DUF2322 PF10084.9 RLN96556.1 - 0.83 9.7 4.2 34 4.6 0.0 4.2 4 2 1 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2322) DUF35_N PF12172.8 RLN96557.1 - 0.0048 16.8 1.3 0.0048 16.8 1.3 2.8 2 1 1 3 3 3 1 Rubredoxin-like zinc ribbon domain (DUF35_N) Myticin-prepro PF10690.9 RLN96557.1 - 2.4 8.4 6.8 1.2 9.4 3.5 2.1 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel Pkinase PF00069.25 RLN96558.1 - 7.9e-51 172.9 0.0 1.2e-50 172.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN96558.1 - 7.8e-37 126.9 0.0 1.3e-36 126.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 RLN96558.1 - 0.0012 19.1 0.1 0.0026 17.9 0.1 1.6 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 RLN96558.1 - 0.0061 15.4 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 RLN96558.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FAM76 PF16046.5 RLN96558.1 - 0.2 11.0 1.2 0.34 10.2 1.2 1.3 1 0 0 1 1 1 0 FAM76 protein PB1-F2 PF11986.8 RLN96558.1 - 0.24 11.6 0.7 0.55 10.5 0.7 1.5 1 0 0 1 1 1 0 Influenza A Proapoptotic protein DUF1640 PF07798.11 RLN96558.1 - 0.57 10.2 4.6 0.1 12.6 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) DUF92 PF01940.16 RLN96560.1 - 1.2e-19 70.7 1.2 1.3e-19 70.6 1.2 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 NPL4 PF05021.15 RLN96562.1 - 0.0055 16.1 0.0 0.0064 15.9 0.0 1.0 1 0 0 1 1 1 1 NPL4 family Hexapep PF00132.24 RLN96563.1 - 4.4e-14 51.6 9.6 3.8e-10 39.1 3.0 3.6 2 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 RLN96563.1 - 1.7e-10 41.0 0.1 3.8e-10 39.9 0.1 1.6 2 0 0 2 2 2 1 Maltose acetyltransferase Hexapep_2 PF14602.6 RLN96563.1 - 4.5e-10 39.1 13.7 1.3e-09 37.7 3.0 4.0 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase PDZ_6 PF17820.1 RLN96564.1 - 0.0018 18.1 0.0 0.0061 16.4 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 RLN96564.1 - 0.011 16.0 0.0 0.045 14.1 0.0 2.0 2 0 0 2 2 2 0 PDZ domain PDZ_2 PF13180.6 RLN96564.1 - 0.12 12.8 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Proteasome PF00227.26 RLN96565.1 - 4.8e-55 186.0 0.0 6.9e-55 185.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RLN96565.1 - 7.4e-14 51.1 0.0 1.3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TACC_C PF05010.14 RLN96565.1 - 0.045 13.5 0.1 0.072 12.9 0.1 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PRK PF00485.18 RLN96566.1 - 5.3e-42 143.8 0.2 7.5e-42 143.3 0.2 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 RLN96566.1 - 2.5e-07 31.3 0.0 4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RLN96566.1 - 5e-05 23.5 0.3 0.00014 22.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 RLN96566.1 - 0.00051 19.3 0.0 0.00095 18.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.6 RLN96566.1 - 0.0018 18.7 0.6 0.47 10.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 RLN96566.1 - 0.002 18.6 0.0 0.0033 17.9 0.0 1.6 1 1 0 1 1 1 1 ABC transporter CoaE PF01121.20 RLN96566.1 - 0.0026 17.4 2.6 0.27 10.9 0.1 2.4 2 0 0 2 2 2 2 Dephospho-CoA kinase Cytidylate_kin PF02224.18 RLN96566.1 - 0.0035 17.1 0.4 0.8 9.4 0.0 2.5 1 1 1 2 2 2 1 Cytidylate kinase T2SSE PF00437.20 RLN96566.1 - 0.021 13.9 0.9 0.042 12.9 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein TsaE PF02367.17 RLN96566.1 - 0.022 14.8 0.0 0.076 13.0 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 RLN96566.1 - 0.034 14.1 0.0 0.15 12.0 0.0 2.1 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 RLN96566.1 - 0.047 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_8 PF12780.7 RLN96566.1 - 0.052 12.9 0.1 0.25 10.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 AAA PF00004.29 RLN96566.1 - 0.06 13.8 0.0 0.2 12.0 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 RLN96566.1 - 0.062 13.5 0.0 0.82 9.9 0.0 2.3 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 RLN96566.1 - 0.064 13.6 0.0 0.14 12.5 0.0 1.6 2 0 0 2 2 1 0 AAA ATPase domain cobW PF02492.19 RLN96566.1 - 0.074 12.6 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 RLN96566.1 - 0.075 13.4 0.0 0.15 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RLN96566.1 - 0.083 13.1 0.0 0.2 11.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 RLN96566.1 - 0.089 12.1 0.0 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 RLN96566.1 - 0.099 12.6 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 RLN96566.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_26 PF13500.6 RLN96566.1 - 0.14 12.0 0.1 0.52 10.1 0.1 2.0 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 RLN96566.1 - 0.17 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ThiF PF00899.21 RLN96567.1 - 6.6e-90 300.7 0.0 3.3e-59 200.2 0.0 3.1 2 1 0 2 2 2 2 ThiF family E1_4HB PF16191.5 RLN96567.1 - 3.5e-23 81.6 0.1 7.1e-23 80.6 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_FCCH PF16190.5 RLN96567.1 - 3.1e-22 78.5 0.2 1.2e-21 76.7 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 FCCH domain UBA_e1_thiolCys PF10585.9 RLN96567.1 - 0.0014 18.6 0.2 0.0029 17.6 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.20 RLN96567.1 - 0.014 15.5 1.5 0.57 10.2 0.1 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Oxidored_FMN PF00724.20 RLN96568.1 - 5.7e-79 265.9 0.0 6.5e-79 265.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Clathrin-link PF09268.10 RLN96568.1 - 0.38 10.2 3.8 0.099 12.0 0.5 1.8 2 0 0 2 2 2 0 Clathrin, heavy-chain linker Ank_4 PF13637.6 RLN96569.1 - 2.5e-35 120.4 19.2 4.9e-05 23.8 0.2 11.3 3 2 11 14 14 14 13 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN96569.1 - 1.3e-31 109.0 9.2 1.3e-05 25.7 0.2 7.0 3 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN96569.1 - 3.1e-30 103.8 16.1 0.00015 22.0 0.0 13.0 5 1 9 14 14 14 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN96569.1 - 2e-15 55.3 6.7 21 6.1 0.0 13.4 14 1 1 15 15 15 0 Ankyrin repeat Ank PF00023.30 RLN96569.1 - 0.0073 16.7 2.1 2.1e+02 2.6 0.0 7.1 7 2 1 8 8 8 0 Ankyrin repeat TGBp3 PF02495.17 RLN96569.1 - 0.067 12.9 0.3 42 3.9 0.0 3.9 5 0 0 5 5 5 0 Triple gene block 3 DEP PF00610.21 RLN96569.1 - 0.15 12.1 10.5 34 4.6 0.0 7.2 9 0 0 9 9 9 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF3322 PF11795.8 RLN96569.1 - 0.16 12.0 1.5 29 4.6 0.0 4.5 3 1 2 5 5 5 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Chorion_S16 PF05836.12 RLN96569.1 - 3.7 7.8 8.2 18 5.6 0.1 4.8 3 1 2 5 5 5 0 Chorion protein S16 TauE PF01925.19 RLN96570.1 - 0.011 15.4 2.5 0.051 13.2 0.2 2.6 3 0 0 3 3 3 0 Sulfite exporter TauE/SafE DUF3671 PF12420.8 RLN96570.1 - 0.07 13.2 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function Ank_2 PF12796.7 RLN96571.1 - 3.4e-42 142.9 3.9 1e-07 32.4 0.1 8.8 4 4 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN96571.1 - 1.4e-39 133.9 16.4 9.3e-06 26.1 0.0 11.6 8 6 3 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN96571.1 - 3.1e-31 107.0 23.6 0.0067 16.7 0.1 15.9 8 2 9 17 17 17 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN96571.1 - 1.6e-22 77.2 10.2 3.9 8.4 0.0 15.8 15 3 2 18 18 18 4 Ankyrin repeat Ank PF00023.30 RLN96571.1 - 6.6e-06 26.3 4.3 49 4.6 0.0 10.0 8 1 2 10 10 10 0 Ankyrin repeat DUF5049 PF16468.5 RLN96571.1 - 0.0023 17.8 0.0 76 3.3 0.0 6.5 7 1 1 8 8 8 0 Domain of unknown function (DUF5049) VbhA PF18495.1 RLN96571.1 - 0.031 14.2 0.1 9.3 6.2 0.0 4.5 3 1 1 4 4 4 0 Antitoxin VbhA DEP PF00610.21 RLN96571.1 - 2.4 8.3 9.0 39 4.4 0.0 6.4 7 1 1 8 8 8 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Ank_2 PF12796.7 RLN96572.1 - 1.1e-46 157.3 6.0 6.4e-11 42.7 0.1 7.3 3 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN96572.1 - 2.8e-43 145.4 14.4 0.00032 20.9 0.1 15.0 7 3 8 15 15 15 13 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN96572.1 - 4.5e-40 135.5 13.1 5.2e-05 23.7 0.0 11.7 6 6 6 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN96572.1 - 8.9e-28 93.3 3.3 0.58 10.9 0.0 15.2 15 1 1 16 16 16 7 Ankyrin repeat Ank PF00023.30 RLN96572.1 - 6.9e-10 38.9 5.5 14 6.3 0.2 10.2 7 4 2 9 9 9 2 Ankyrin repeat DUF5049 PF16468.5 RLN96572.1 - 0.17 11.8 0.0 30 4.6 0.0 4.1 5 1 0 5 5 5 0 Domain of unknown function (DUF5049) Helicase_C_3 PF13625.6 RLN96573.1 - 0.031 14.4 0.1 0.08 13.1 0.1 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain PGAP1 PF07819.13 RLN96574.1 - 0.02 14.6 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 RLN96574.1 - 0.024 15.2 0.0 0.028 15.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 RLN96574.1 - 0.082 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.15 RLN96574.1 - 0.17 11.0 0.2 0.29 10.2 0.2 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 RLN96575.1 - 0.014 15.1 0.3 0.033 13.9 0.3 1.6 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 RLN96575.1 - 0.029 15.0 0.4 0.098 13.2 0.4 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family RebB PF11747.8 RLN96575.1 - 0.051 13.7 7.1 0.34 11.0 1.5 2.9 2 0 0 2 2 2 0 Killing trait DUF676 PF05057.14 RLN96575.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 RLN96575.1 - 0.16 11.2 0.1 0.29 10.4 0.1 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN96576.1 - 0.0024 18.5 0.0 0.0034 18.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 RLN96576.1 - 0.028 14.2 0.2 0.13 12.0 0.2 2.1 1 1 0 1 1 1 0 PGAP1-like protein cNMP_binding PF00027.29 RLN96577.1 - 1.2e-12 47.8 0.0 2e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN96577.1 - 6.8e-06 25.5 7.0 1.2e-05 24.7 7.0 1.3 1 0 0 1 1 1 1 Ion transport protein GCIP PF13324.6 RLN96577.1 - 0.53 9.8 1.9 0.97 9.0 1.9 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CDC50 PF03381.15 RLN96578.1 - 2.8e-86 289.5 0.2 4e-86 289.0 0.1 1.3 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Orbi_NS3 PF01616.16 RLN96578.1 - 0.17 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Orbivirus NS3 DUF202 PF02656.15 RLN96578.1 - 6.8 7.2 8.4 2.4 8.7 0.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Pkinase PF00069.25 RLN96579.1 - 1.9e-47 161.9 0.0 3.4e-47 161.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN96579.1 - 2.4e-17 63.1 0.0 2.4e-16 59.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RLN96579.1 - 0.0072 16.3 0.2 0.026 14.4 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family PH PF00169.29 RLN96580.1 - 0.00016 22.1 0.0 0.00028 21.4 0.0 1.4 1 0 0 1 1 1 1 PH domain DUF4407 PF14362.6 RLN96580.1 - 0.5 9.7 7.6 0.9 8.8 7.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_GP20 PF06810.11 RLN96580.1 - 0.68 9.7 6.9 1.5 8.7 6.9 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 FAM184 PF15665.5 RLN96580.1 - 0.72 9.6 14.6 0.14 12.0 10.4 1.8 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B Cytochrom_B562 PF07361.11 RLN96580.1 - 1.4 9.6 5.8 0.86 10.3 2.2 2.4 2 0 0 2 2 2 0 Cytochrome b562 Spectrin PF00435.21 RLN96580.1 - 2 8.9 12.3 3.9 8.0 4.6 2.9 1 1 1 2 2 2 0 Spectrin repeat CENP-H PF05837.12 RLN96580.1 - 5.7 7.4 11.8 1.9 8.9 8.4 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) PGAP1 PF07819.13 RLN96581.1 - 0.046 13.4 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 RLN96581.1 - 0.056 14.0 0.0 0.097 13.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PI3_PI4_kinase PF00454.27 RLN96582.1 - 2.6e-34 119.2 0.6 2.6e-32 112.6 0.2 2.7 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 RLN96582.1 - 5.8e-06 25.8 0.1 1.7e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 RLN96582.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) RSN1_TM PF13967.6 RLN96582.1 - 0.23 11.2 1.8 0.66 9.7 1.8 1.8 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport BatA PF07584.11 RLN96582.1 - 4.8 7.6 13.0 1.1 9.7 3.2 2.9 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal DUF4632 PF15451.6 RLN96582.1 - 6.6 6.9 5.8 1.1 9.4 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4632) RRM_1 PF00076.22 RLN96583.1 - 1.8e-06 27.7 0.0 0.00056 19.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vps39_2 PF10367.9 RLN96584.1 - 2e-22 79.7 0.0 2.2e-21 76.3 0.0 2.7 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 RLN96584.1 - 2.3e-16 60.0 0.5 7.6e-16 58.4 0.2 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 RLN96584.1 - 7.2e-06 25.8 0.0 0.00058 19.6 0.0 2.2 2 0 0 2 2 2 2 CNH domain Rsm1 PF08600.10 RLN96584.1 - 0.09 12.9 0.1 5.8 7.2 0.0 2.8 2 0 0 2 2 2 0 Rsm1-like SAP PF02037.27 RLN96586.1 - 0.0011 18.6 0.9 0.0022 17.7 0.9 1.6 1 0 0 1 1 1 1 SAP domain IQ PF00612.27 RLN96586.1 - 0.051 13.4 1.1 0.051 13.4 1.1 3.2 4 0 0 4 4 4 0 IQ calmodulin-binding motif RCC1 PF00415.18 RLN96587.1 - 5.4e-43 145.4 23.5 1.6e-12 47.8 0.2 7.0 6 2 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat WW PF00397.26 RLN96587.1 - 4.1e-24 84.4 27.5 2.5e-07 30.7 1.0 6.5 6 0 0 6 6 6 4 WW domain RCC1_2 PF13540.6 RLN96587.1 - 7.2e-20 70.3 39.4 1.1e-08 34.6 1.3 7.2 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.27 RLN96587.1 - 0.011 15.4 33.4 0.082 12.7 0.9 6.6 6 0 0 6 6 6 0 IQ calmodulin-binding motif Glyco_hyd_101C PF17451.2 RLN96587.1 - 0.17 12.2 8.8 15 5.9 0.3 5.0 4 1 0 5 5 5 0 Glycosyl hydrolase 101 beta sandwich domain zf-C3HC4_3 PF13920.6 RLN96588.1 - 0.0018 18.1 15.6 0.0034 17.2 15.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN96588.1 - 0.0086 16.4 15.0 0.0086 16.4 15.0 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 RLN96588.1 - 0.01 15.7 14.2 0.01 15.7 14.2 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RLN96588.1 - 0.011 15.5 14.8 0.024 14.5 14.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 RLN96588.1 - 0.13 12.1 12.1 0.27 11.1 12.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-WRNIP1_ubi PF18279.1 RLN96588.1 - 0.13 12.9 2.2 0.86 10.4 0.2 2.9 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-C3HC4 PF00097.25 RLN96588.1 - 1.1 9.2 18.3 0.31 10.9 14.7 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ras PF00071.22 RLN96589.1 - 1.1e-40 138.8 0.0 1.4e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN96589.1 - 7.6e-25 87.5 0.0 1e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN96589.1 - 3e-10 39.8 0.0 4.2e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RLN96589.1 - 0.00028 21.0 0.0 0.00038 20.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RLN96589.1 - 0.0011 18.4 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 RLN96589.1 - 0.021 14.7 0.0 0.23 11.3 0.0 2.3 2 1 1 3 3 3 0 RsgA GTPase PAX PF00292.18 RLN96589.1 - 0.047 13.6 0.0 0.07 13.1 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain AAA_22 PF13401.6 RLN96589.1 - 0.082 13.2 0.0 0.12 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RLN96589.1 - 0.11 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Ank_2 PF12796.7 RLN96590.1 - 1e-06 29.2 2.8 0.44 11.2 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN96590.1 - 4.3e-06 26.7 3.7 0.11 13.1 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 RLN96590.1 - 5.5e-06 26.8 2.5 0.001 19.6 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN96590.1 - 9.6e-05 22.6 2.7 0.029 14.7 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN96590.1 - 0.0041 17.5 6.5 0.35 11.4 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat HECT PF00632.25 RLN96591.1 - 7e-39 134.1 0.0 1e-38 133.6 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SGS PF05002.15 RLN96592.1 - 7.6e-29 99.6 4.6 7.6e-29 99.6 4.6 2.1 2 0 0 2 2 2 1 SGS domain CS PF04969.16 RLN96592.1 - 5.4e-11 43.4 1.1 1.2e-10 42.2 1.1 1.5 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 RLN96592.1 - 5.9e-10 38.5 14.2 0.0027 17.5 2.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN96592.1 - 6.4e-09 35.3 18.9 0.0034 17.4 0.9 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN96592.1 - 6.4e-05 22.6 2.4 6.4e-05 22.6 2.4 2.6 2 1 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 RLN96592.1 - 0.00011 22.3 4.1 0.00013 22.1 1.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN96592.1 - 0.0096 16.5 27.2 0.02 15.5 14.5 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN96592.1 - 0.01 16.0 14.0 0.057 13.6 8.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN96592.1 - 0.043 14.3 18.4 1 9.9 10.2 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN96592.1 - 0.089 13.0 8.8 0.19 12.0 8.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 RLN96592.1 - 0.1 13.3 1.1 0.1 13.3 1.1 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 RLN96592.1 - 0.47 10.8 12.1 8.2 6.9 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat MMR_HSR1 PF01926.23 RLN96593.1 - 1.4e-18 67.0 0.1 2.6e-18 66.2 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RLN96593.1 - 1e-07 31.7 0.3 3e-06 26.9 0.4 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 RLN96593.1 - 3.2e-07 30.0 0.7 8.2e-07 28.7 0.4 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 RLN96593.1 - 3.3e-07 30.5 0.9 0.018 15.1 0.1 2.5 1 1 1 2 2 2 2 Dynamin family KH_2 PF07650.17 RLN96593.1 - 9.4e-07 28.6 0.0 2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 KH domain AIG1 PF04548.16 RLN96593.1 - 1.5e-05 24.4 0.2 2.5e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 RLN96593.1 - 1.9e-05 24.7 1.9 0.036 14.0 1.0 2.7 2 1 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 RLN96593.1 - 0.00011 22.1 0.5 0.00045 20.1 0.4 1.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein cobW PF02492.19 RLN96593.1 - 0.00085 19.0 0.2 0.0015 18.1 0.2 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 RLN96593.1 - 0.0074 15.8 0.4 0.026 14.0 0.4 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family TniB PF05621.11 RLN96593.1 - 0.019 14.4 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 RLN96593.1 - 0.026 14.7 0.0 0.057 13.6 0.0 1.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Histone PF00125.24 RLN96595.1 - 1.6e-28 99.7 1.5 2.2e-21 76.6 0.1 2.0 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 Cas_Cas5d PF09704.10 RLN96595.1 - 0.0044 16.9 0.2 0.0077 16.1 0.2 1.5 1 1 1 2 2 2 1 CRISPR-associated protein (Cas_Cas5) Conotoxin_I2 PF17557.2 RLN96595.1 - 0.054 13.6 0.2 0.074 13.2 0.2 1.2 1 0 0 1 1 1 0 I2-superfamily conotoxins PAS PF00989.25 RLN96596.1 - 1.4e-272 885.2 11.8 3.9e-23 81.6 0.0 14.2 14 0 0 14 14 14 14 PAS fold PAS_4 PF08448.10 RLN96596.1 - 2.1e-175 572.0 0.5 1.6e-12 47.7 0.0 14.5 14 0 0 14 14 14 14 PAS fold PAS_9 PF13426.7 RLN96596.1 - 1.8e-159 519.8 30.2 8.8e-12 45.2 0.0 14.3 14 0 0 14 14 14 14 PAS domain PAS_3 PF08447.12 RLN96596.1 - 1.6e-87 287.9 0.0 1.5e-05 25.2 0.0 14.3 14 0 0 14 14 14 14 PAS fold PAS_8 PF13188.7 RLN96596.1 - 1.2e-49 165.6 10.3 0.0022 17.9 0.0 14.7 14 0 0 14 14 14 13 PAS domain PAS_10 PF13596.6 RLN96596.1 - 2.4e-34 118.1 10.9 0.048 14.3 0.0 14.1 14 0 0 14 14 14 7 PAS domain HATPase_c PF02518.26 RLN96596.1 - 6.4e-25 87.8 0.0 1.9e-24 86.3 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 RLN96596.1 - 4.3e-20 72.0 0.0 1.1e-19 70.6 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 RLN96596.1 - 1.1e-16 60.7 0.0 3.3e-16 59.1 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_7 PF12860.7 RLN96596.1 - 2.2e-12 47.1 32.3 0.89 9.7 0.0 15.6 14 10 0 14 14 14 3 PAS fold Hpt PF01627.23 RLN96596.1 - 1.2e-08 35.1 1.2 3.9e-08 33.4 1.2 2.0 1 0 0 1 1 1 1 Hpt domain sCache_3_3 PF17202.4 RLN96596.1 - 2.6e-05 24.6 13.4 17 5.8 0.0 10.7 13 0 0 13 13 10 0 Single cache domain 3 DUF3189 PF11385.8 RLN96596.1 - 0.00032 20.6 0.2 35 4.2 0.0 5.6 5 0 0 5 5 5 0 Protein of unknown function (DUF3189) HlyD PF00529.20 RLN96596.1 - 0.0022 17.8 1.3 55 3.8 0.0 5.9 6 0 0 6 6 6 0 HlyD membrane-fusion protein of T1SS Pilin_GH PF16734.5 RLN96596.1 - 0.078 13.3 0.0 68 3.8 0.0 4.9 6 0 0 6 6 6 0 Type IV pilin-like G and H, putative HATPase_c_3 PF13589.6 RLN96596.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DENN PF02141.21 RLN96597.1 - 1e-37 129.9 0.1 2.4e-37 128.7 0.1 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain RGS PF00615.19 RLN96597.1 - 2.6e-11 43.8 0.0 1.1e-05 25.6 0.0 3.2 2 1 0 2 2 2 2 Regulator of G protein signaling domain dDENN PF03455.19 RLN96597.1 - 0.00031 20.7 0.4 0.00085 19.3 0.4 1.7 1 0 0 1 1 1 1 dDENN domain Avl9 PF09794.9 RLN96597.1 - 0.0073 15.0 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 Transport protein Avl9 uDENN PF03456.18 RLN96597.1 - 0.017 15.9 0.1 0.058 14.1 0.1 1.9 1 0 0 1 1 1 0 uDENN domain FCH PF00611.23 RLN96598.1 - 5.6e-06 26.5 0.7 5.6e-06 26.5 0.7 1.9 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Torus PF16131.5 RLN96598.1 - 0.07 13.8 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Torus domain PhoU_div PF01865.16 RLN96600.1 - 0.11 11.8 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF47 RNase_HII PF01351.18 RLN96601.1 - 2.9e-47 161.1 0.0 2e-46 158.3 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease HII PX PF00787.24 RLN96601.1 - 1.4e-19 70.1 0.0 3.6e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 PX domain Peptidase_C92 PF05708.12 RLN96601.1 - 2.6e-06 27.7 0.0 1.8e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family PH PF00169.29 RLN96601.1 - 0.039 14.5 0.0 0.17 12.4 0.0 2.1 2 0 0 2 2 2 0 PH domain PAS PF00989.25 RLN96603.1 - 6.5e-204 664.0 8.5 1.4e-20 73.4 0.0 11.3 11 0 0 11 11 11 11 PAS fold PAS_4 PF08448.10 RLN96603.1 - 4.2e-126 413.2 4.1 2.1e-12 47.3 0.0 11.4 11 0 0 11 11 11 11 PAS fold PAS_9 PF13426.7 RLN96603.1 - 1.4e-110 362.7 18.8 5.1e-11 42.8 0.0 11.6 12 0 0 12 12 11 11 PAS domain PAS_3 PF08447.12 RLN96603.1 - 1.9e-59 197.9 0.0 2.9e-09 37.1 0.0 10.7 11 0 0 11 11 11 10 PAS fold PAS_8 PF13188.7 RLN96603.1 - 4.9e-39 131.7 4.9 0.019 15.0 0.0 11.5 11 0 0 11 11 11 10 PAS domain HATPase_c PF02518.26 RLN96603.1 - 4e-27 94.9 0.0 1.4e-26 93.2 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_10 PF13596.6 RLN96603.1 - 1.4e-22 80.2 6.6 0.044 14.4 0.0 9.9 11 0 0 11 11 10 4 PAS domain Response_reg PF00072.24 RLN96603.1 - 6e-21 74.7 0.0 2.5e-20 72.7 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 RLN96603.1 - 8.9e-17 60.9 0.8 4.8e-16 58.5 0.1 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_7 PF12860.7 RLN96603.1 - 5.1e-16 58.9 14.7 0.52 10.5 0.1 12.7 12 5 0 12 12 12 3 PAS fold Hpt PF01627.23 RLN96603.1 - 9.6e-07 29.0 0.6 3.6e-06 27.1 0.6 2.1 1 0 0 1 1 1 1 Hpt domain sCache_3_3 PF17202.4 RLN96603.1 - 9.9e-05 22.7 6.4 26 5.3 0.0 7.3 8 0 0 8 8 7 0 Single cache domain 3 DUF5588 PF17826.1 RLN96603.1 - 0.00034 19.6 1.0 2.4 6.9 0.0 4.8 6 0 0 6 6 6 1 Family of unknown function (DUF5588) HlyD PF00529.20 RLN96603.1 - 0.029 14.2 0.6 13 5.7 0.0 4.7 5 0 0 5 5 5 0 HlyD membrane-fusion protein of T1SS GDP_Man_Dehyd PF16363.5 RLN96603.1 - 0.047 13.1 0.0 3.3 7.0 0.0 2.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Microtub_bd PF16796.5 RLN96603.1 - 0.094 12.6 0.1 18 5.2 0.0 3.4 3 0 0 3 3 3 0 Microtubule binding VID27_N PF17748.1 RLN96603.1 - 0.16 11.8 0.3 8.6 6.2 0.0 3.0 3 0 0 3 3 3 0 VID27 N-terminal region PUB PF09409.10 RLN96604.1 - 1.8e-10 40.6 0.0 3.3e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 PUB domain VSG_B PF13206.6 RLN96604.1 - 0.14 11.4 8.9 0.18 11.1 8.9 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain Borrelia_P83 PF05262.11 RLN96604.1 - 1.4 7.4 16.4 1.7 7.0 16.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PH PF00169.29 RLN96605.1 - 6.6e-11 42.7 0.0 0.0097 16.4 0.3 4.4 3 1 0 3 3 3 3 PH domain PH_11 PF15413.6 RLN96605.1 - 2.6e-06 27.8 0.1 2.3 8.7 0.1 4.8 3 2 0 3 3 3 3 Pleckstrin homology domain Herpes_pp85 PF04637.12 RLN96605.1 - 1.5 7.1 6.1 2.5 6.4 6.1 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) PX PF00787.24 RLN96606.1 - 1.3e-07 31.6 0.1 2.4e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 PX domain YL1 PF05764.13 RLN96606.1 - 0.24 11.5 4.7 0.33 11.0 4.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein SNF2_N PF00176.23 RLN96607.1 - 6.4e-57 192.9 0.1 1.1e-56 192.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN96607.1 - 1.2e-19 70.7 0.0 7e-19 68.2 0.0 2.4 2 1 1 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 RLN96607.1 - 1.8e-09 37.2 0.1 4.3e-05 22.8 0.0 2.7 2 1 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 GREB1 PF15782.5 RLN96607.1 - 0.7 7.0 10.9 1.1 6.3 10.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAS PF00989.25 RLN96608.1 - 1.6e-33 115.1 0.0 4.9e-13 49.1 0.0 3.2 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.7 RLN96608.1 - 6.3e-23 81.0 0.0 3.2e-10 40.2 0.0 3.1 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 RLN96608.1 - 2.2e-20 73.0 2.1 1.3e-09 38.3 0.1 3.1 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 RLN96608.1 - 5.3e-15 55.0 0.1 1e-06 28.6 0.0 3.3 3 0 0 3 3 3 2 PAS domain PAS_7 PF12860.7 RLN96608.1 - 1.4e-07 31.7 0.3 0.034 14.3 0.0 3.5 4 0 0 4 4 4 2 PAS fold PAS_3 PF08447.12 RLN96608.1 - 4e-07 30.2 0.0 0.0039 17.4 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_10 PF13596.6 RLN96608.1 - 1.1e-05 26.0 0.0 0.034 14.7 0.0 2.8 3 0 0 3 3 3 2 PAS domain PAS_11 PF14598.6 RLN96608.1 - 0.00084 19.4 0.0 0.81 9.8 0.0 2.3 2 0 0 2 2 2 2 PAS domain MLTR_LBD PF17765.1 RLN96608.1 - 0.024 14.8 0.2 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain MycE_N PF17843.1 RLN96608.1 - 0.17 12.4 1.6 0.63 10.6 0.1 2.3 2 1 0 2 2 2 0 MycE methyltransferase N-terminal Ras PF00071.22 RLN96609.1 - 4.2e-48 163.0 0.2 5.1e-48 162.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN96609.1 - 6.8e-26 90.8 0.1 1.1e-25 90.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN96609.1 - 1.4e-12 47.4 0.4 1.8e-12 47.1 0.4 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RLN96609.1 - 0.00035 20.2 0.2 0.0012 18.5 0.2 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 RLN96609.1 - 0.16 11.3 0.1 0.2 11.0 0.1 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GETHR PF05671.11 RLN96611.1 - 0.075 12.4 0.2 0.15 11.4 0.2 1.5 1 0 0 1 1 1 0 GETHR pentapeptide repeat (5 copies) CX9C PF16860.5 RLN96611.1 - 0.48 10.5 3.8 1.6 8.8 0.3 2.3 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Ubiq_cyt_C_chap PF03981.12 RLN96612.1 - 2.3e-23 82.9 0.1 3.3e-23 82.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone WW PF00397.26 RLN96612.1 - 3.5e-05 23.8 0.2 6.4e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 WW domain Sas10 PF09368.10 RLN96613.1 - 4.4e-26 91.2 11.2 4.4e-26 91.2 11.2 2.3 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 RLN96613.1 - 5.5e-09 36.5 1.6 5.5e-09 36.5 1.6 2.7 2 0 0 2 2 2 1 Sas10/Utp3/C1D family CARMIL_C PF16000.5 RLN96613.1 - 0.01 15.5 0.1 0.01 15.5 0.1 2.6 3 0 0 3 3 3 0 CARMIL C-terminus Acylphosphatase PF00708.18 RLN96614.1 - 3.4e-12 46.6 0.1 5e-12 46.1 0.1 1.2 1 0 0 1 1 1 1 Acylphosphatase Nop PF01798.18 RLN96615.1 - 3.8e-85 285.0 0.1 3.8e-85 285.0 0.1 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin RNA_polI_A34 PF08208.11 RLN96615.1 - 0.058 13.5 35.9 0.09 12.9 35.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF4604 PF15377.6 RLN96615.1 - 0.51 10.7 30.7 0.93 9.9 30.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RR_TM4-6 PF06459.12 RLN96615.1 - 0.81 9.5 22.4 1.1 9.0 22.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.12 RLN96615.1 - 0.84 9.9 13.5 1.1 9.5 13.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SAPS PF04499.15 RLN96615.1 - 6 5.5 11.0 7.5 5.2 11.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ETC_C1_NDUFA5 PF04716.14 RLN96616.1 - 1.2e-17 63.5 0.1 1.8e-17 62.9 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Lar_N PF09861.9 RLN96617.1 - 2e-09 36.9 0.0 7.2e-09 35.1 0.0 1.8 1 1 0 1 1 1 1 Lactate racemase N-terminal domain DUF2012 PF09430.10 RLN96618.1 - 1.3e-21 77.0 0.0 2e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 RLN96618.1 - 0.0018 18.5 0.1 0.0027 17.9 0.1 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF2846 PF11008.8 RLN96618.1 - 0.022 14.8 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) PP-binding PF00550.25 RLN96620.1 - 1e-10 41.8 0.1 1.5e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 RLN96620.1 - 0.00023 21.3 0.3 0.00031 20.9 0.3 1.2 1 0 0 1 1 1 1 Acyl-carrier Cmc1 PF08583.10 RLN96621.1 - 1.2e-06 28.4 1.1 2.1e-06 27.7 1.1 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like MerR-DNA-bind PF09278.11 RLN96621.1 - 0.1 13.2 3.9 0.58 10.7 0.0 2.9 3 0 0 3 3 3 0 MerR, DNA binding Prefoldin_2 PF01920.20 RLN96622.1 - 2.8e-18 65.8 0.6 2.8e-18 65.8 0.6 2.6 3 0 0 3 3 3 1 Prefoldin subunit zf-Tim10_DDP PF02953.15 RLN96622.1 - 1.8e-17 62.7 3.2 3.8e-17 61.7 3.2 1.6 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DASH_Dad3 PF08656.10 RLN96622.1 - 0.026 14.6 0.3 0.026 14.6 0.3 2.4 4 0 0 4 4 4 0 DASH complex subunit Dad3 FapA PF03961.13 RLN96622.1 - 0.062 11.9 0.5 0.098 11.2 0.5 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4795 PF16043.5 RLN96622.1 - 0.078 12.6 4.2 2.9 7.4 0.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) STAT_alpha PF01017.20 RLN96622.1 - 0.42 10.5 7.3 6.2 6.7 0.6 3.1 3 0 0 3 3 3 0 STAT protein, all-alpha domain DUF1664 PF07889.12 RLN96622.1 - 1.4 8.9 6.9 0.18 11.8 1.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) GAT PF03127.14 RLN96622.1 - 3.8 7.9 10.3 4.2 7.8 2.0 3.7 3 1 1 4 4 4 0 GAT domain rRNA_processing PF08524.11 RLN96623.1 - 2.1e-13 50.5 19.9 8.1e-13 48.6 10.0 2.1 2 0 0 2 2 2 2 rRNA processing ANAPC4_WD40 PF12894.7 RLN96625.1 - 3.7e-12 46.4 3.3 0.043 14.1 0.0 6.4 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RLN96625.1 - 8.9e-08 32.7 16.2 5.6 8.0 0.0 7.9 8 0 0 8 8 8 4 WD domain, G-beta repeat PQQ_2 PF13360.6 RLN96625.1 - 0.0019 17.8 1.5 0.0095 15.5 0.5 2.7 1 1 0 2 2 2 1 PQQ-like domain Frtz PF11768.8 RLN96625.1 - 0.0046 15.3 0.0 0.033 12.5 0.0 2.0 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz HPS3_N PF14761.6 RLN96625.1 - 0.061 12.8 0.0 2.1 7.8 0.0 3.0 2 1 2 4 4 4 0 Hermansky-Pudlak syndrome 3 WD40_like PF17005.5 RLN96625.1 - 0.15 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain Pkinase_Tyr PF07714.17 RLN96626.1 - 1.2e-41 142.7 0.0 1.1e-36 126.5 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN96626.1 - 2.7e-38 131.8 0.0 5.1e-33 114.6 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Cystatin PF00031.21 RLN96626.1 - 0.031 14.5 0.1 1.9 8.8 0.0 2.6 1 1 1 2 2 2 0 Cystatin domain Pkinase_fungal PF17667.1 RLN96626.1 - 0.043 12.6 0.0 0.086 11.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase WD40 PF00400.32 RLN96627.1 - 1e-05 26.2 5.2 2.9 8.9 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN96627.1 - 0.001 19.3 0.1 3.2 8.1 0.0 3.2 1 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 RLN96627.1 - 0.0064 16.9 0.1 0.97 10.0 0.0 3.2 3 0 0 3 3 3 1 PQQ-like domain PHTB1_N PF14727.6 RLN96627.1 - 0.074 12.4 0.0 0.13 11.6 0.0 1.4 1 1 0 1 1 1 0 PTHB1 N-terminus WD40_like PF17005.5 RLN96627.1 - 0.078 12.3 0.1 0.32 10.3 0.1 1.7 1 1 1 2 2 2 0 WD40-like domain Antimicrobial22 PF16047.5 RLN96627.1 - 0.079 12.8 1.1 0.19 11.6 1.1 1.7 1 0 0 1 1 1 0 Frog antimicrobial peptide Glyco_transf_64 PF09258.10 RLN96627.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 64 domain YL1 PF05764.13 RLN96627.1 - 4.2 7.4 5.8 6 6.9 5.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Pkinase PF00069.25 RLN96628.1 - 2.8e-28 99.0 0.0 4.8e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN96628.1 - 1.3e-25 90.2 0.0 2.8e-25 89.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase SCP2_2 PF13530.6 RLN96630.1 - 0.048 14.1 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Sterol carrier protein domain SCP2 PF02036.17 RLN96630.1 - 0.076 13.5 0.0 0.36 11.3 0.0 2.1 1 1 0 1 1 1 0 SCP-2 sterol transfer family PDZ PF00595.24 RLN96631.1 - 3.5e-07 30.5 0.0 2.9e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 RLN96631.1 - 4.4e-06 26.5 0.0 0.031 14.1 0.0 3.0 3 0 0 3 3 3 2 PDZ domain Aldo_ket_red PF00248.21 RLN96633.1 - 3e-08 33.2 0.0 4.3e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Dimer_Tnp_hAT PF05699.14 RLN96633.1 - 0.027 14.2 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region ALMS_motif PF15309.6 RLN96637.1 - 6.8e-09 36.3 16.7 6.8e-09 36.3 16.7 5.4 5 2 2 7 7 7 1 ALMS motif AAT PF03417.16 RLN96638.1 - 2.7e-23 82.9 0.0 4.1e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DnaJ PF00226.31 RLN96639.1 - 3.4e-25 87.9 0.2 5.5e-25 87.3 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain AAA PF00004.29 RLN96640.1 - 7.3e-31 107.3 0.0 2.1e-30 105.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN96640.1 - 7.3e-09 36.0 0.1 4.8e-08 33.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN96640.1 - 1.5e-07 32.0 0.0 4.6e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 RLN96640.1 - 1.8e-05 24.7 0.1 3.3e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 RLN96640.1 - 9.1e-05 23.0 0.0 0.00021 21.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 RLN96640.1 - 0.00029 20.8 0.0 0.0011 19.0 0.0 1.9 2 1 0 2 2 1 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 RLN96640.1 - 0.00032 20.9 0.0 0.001 19.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 RLN96640.1 - 0.00062 19.6 0.1 0.003 17.3 0.0 2.1 2 1 0 2 2 2 1 Cytidylate kinase TsaE PF02367.17 RLN96640.1 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 RLN96640.1 - 0.0014 18.1 0.1 1.4 8.2 0.0 2.3 2 0 0 2 2 2 2 KaiC RuvB_N PF05496.12 RLN96640.1 - 0.002 17.9 0.0 0.0046 16.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 RLN96640.1 - 0.0023 18.2 0.0 0.0098 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 RLN96640.1 - 0.0024 17.9 0.1 0.0062 16.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 RLN96640.1 - 0.0032 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RLN96640.1 - 0.0034 17.1 0.0 0.0094 15.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RLN96640.1 - 0.0049 16.6 0.0 0.018 14.8 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 RLN96640.1 - 0.0062 16.6 0.1 0.09 12.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 RLN96640.1 - 0.0062 16.1 0.0 0.24 10.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 RLN96640.1 - 0.0078 16.6 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 RLN96640.1 - 0.0086 15.6 0.0 0.047 13.2 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_19 PF13245.6 RLN96640.1 - 0.014 15.7 0.1 0.053 13.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 RLN96640.1 - 0.024 13.8 0.3 0.24 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TIP49 PF06068.13 RLN96640.1 - 0.024 13.8 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 RLN96640.1 - 0.026 14.2 0.0 0.062 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.14 RLN96640.1 - 0.032 14.4 0.0 0.099 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 RLN96640.1 - 0.034 14.0 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain PhoH PF02562.16 RLN96640.1 - 0.061 12.8 0.0 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein SPC25 PF06703.11 RLN96640.1 - 0.079 12.7 0.0 0.19 11.5 0.0 1.6 2 0 0 2 2 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) AAA_17 PF13207.6 RLN96640.1 - 0.088 13.2 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 RLN96640.1 - 0.09 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 RLN96640.1 - 0.097 13.2 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.21 RLN96640.1 - 0.12 11.8 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 RLN96640.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase CPT PF07931.12 RLN96640.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein KAP_NTPase PF07693.14 RLN96640.1 - 0.13 11.4 0.1 16 4.6 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain PduV-EutP PF10662.9 RLN96640.1 - 0.18 11.6 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation GAF PF01590.26 RLN96641.1 - 0.1 13.3 0.0 0.44 11.2 0.0 2.0 1 1 0 1 1 1 0 GAF domain DUF3357 PF11837.8 RLN96641.1 - 3.3 8.2 5.0 20 5.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) PH PF00169.29 RLN96642.1 - 5.1e-08 33.4 0.0 1.5e-07 31.9 0.0 1.9 1 0 0 1 1 1 1 PH domain Pkinase PF00069.25 RLN96642.1 - 0.00014 21.4 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF1658 PF07871.11 RLN96642.1 - 0.39 10.7 4.9 0.58 10.2 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) SPC12 PF06645.13 RLN96644.1 - 1.2e-22 79.7 1.1 1.4e-22 79.5 1.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) NAP PF00956.18 RLN96646.1 - 1.1e-06 28.0 11.2 0.0086 15.3 0.0 3.9 2 2 2 4 4 4 2 Nucleosome assembly protein (NAP) SecA_SW PF07516.13 RLN96646.1 - 0.018 15.1 0.3 0.029 14.4 0.2 1.3 1 1 0 1 1 1 0 SecA Wing and Scaffold domain G-alpha PF00503.20 RLN96646.1 - 0.045 12.9 0.2 0.057 12.6 0.2 1.1 1 0 0 1 1 1 0 G-protein alpha subunit CENP-H PF05837.12 RLN96646.1 - 0.089 13.2 5.2 0.067 13.6 2.2 2.0 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Frigida PF07899.11 RLN96646.1 - 0.13 11.5 5.4 0.18 11.0 5.4 1.1 1 0 0 1 1 1 0 Frigida-like protein DASH_Duo1 PF08651.10 RLN96646.1 - 0.18 11.6 5.2 0.085 12.6 2.6 1.7 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF641 PF04859.12 RLN96646.1 - 0.3 11.4 5.7 0.5 10.7 5.7 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DDE_Tnp_IS66 PF03050.14 RLN96646.1 - 0.49 9.8 3.2 0.87 9.0 3.2 1.3 1 0 0 1 1 1 0 Transposase IS66 family Retrotran_gag_2 PF14223.6 RLN96647.1 - 3.2e-10 39.8 0.0 1.7e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 RLN96647.1 - 0.0059 16.6 3.0 0.0059 16.6 3.0 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 RLN96647.1 - 0.011 15.7 1.3 0.024 14.6 1.3 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 RLN96647.1 - 1.7 8.6 4.4 0.78 9.6 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle Glyco_hydro_5_C PF18564.1 RLN96648.1 - 1.6e-17 63.8 0.0 2.7e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 RLN96648.1 - 5e-12 45.8 0.0 1.8e-09 37.4 0.0 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Sec16_C PF12931.7 RLN96649.1 - 7.7e-49 167.0 0.1 1.2e-48 166.3 0.1 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 RLN96649.1 - 9.2e-15 55.3 0.6 1.5e-12 48.2 0.0 2.9 3 0 0 3 3 3 1 Vesicle coat trafficking protein Sec16 mid-region DAG_kinase_N PF14513.6 RLN96649.1 - 8.4e-05 22.8 1.0 0.00089 19.5 0.0 2.3 2 0 0 2 2 2 1 Diacylglycerol kinase N-terminus RabGAP-TBC PF00566.18 RLN96649.1 - 0.032 13.9 0.0 0.032 13.9 0.0 1.8 2 0 0 2 2 2 0 Rab-GTPase-TBC domain IER PF05760.12 RLN96649.1 - 0.19 12.0 5.0 0.52 10.6 5.0 1.7 1 0 0 1 1 1 0 Immediate early response protein (IER) Sec16 PF12932.7 RLN96650.1 - 3.4e-06 27.6 0.8 1.6e-05 25.5 0.1 2.5 2 1 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region EphA2_TM PF14575.6 RLN96651.1 - 0.00025 21.8 0.0 0.00069 20.4 0.0 1.8 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 RLN96651.1 - 0.0011 18.6 3.4 0.0024 17.6 3.4 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DAP10 PF07213.11 RLN96651.1 - 0.0023 17.9 3.5 0.0023 17.8 2.1 1.8 1 1 0 1 1 1 1 DAP10 membrane protein Syndecan PF01034.20 RLN96651.1 - 0.0024 17.7 0.4 0.005 16.7 0.4 1.4 1 0 0 1 1 1 1 Syndecan domain Amnionless PF14828.6 RLN96651.1 - 0.0024 16.8 0.0 0.0034 16.3 0.0 1.1 1 0 0 1 1 1 1 Amnionless Tweety PF04906.13 RLN96651.1 - 0.0037 16.0 0.1 0.0055 15.4 0.1 1.2 1 0 0 1 1 1 1 Tweety Cadherin_C_2 PF16492.5 RLN96651.1 - 0.0042 17.8 0.0 0.013 16.3 0.0 1.8 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal TMEM154 PF15102.6 RLN96651.1 - 0.0062 16.4 1.1 0.026 14.4 1.1 2.0 1 1 0 1 1 1 1 TMEM154 protein family Podoplanin PF05808.11 RLN96651.1 - 0.0089 16.1 0.6 0.016 15.3 0.6 1.4 1 0 0 1 1 1 1 Podoplanin Mid2 PF04478.12 RLN96651.1 - 0.013 15.3 0.9 0.025 14.4 0.9 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor CYYR1 PF10873.8 RLN96651.1 - 0.02 15.3 1.4 0.02 15.3 1.4 1.8 2 0 0 2 2 1 0 Cysteine and tyrosine-rich protein 1 DUF5305 PF17231.2 RLN96651.1 - 0.023 14.1 0.0 0.046 13.1 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5305) SKG6 PF08693.10 RLN96651.1 - 0.092 12.2 4.2 0.21 11.0 4.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CD34_antigen PF06365.12 RLN96651.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family ECSCR PF15820.5 RLN96651.1 - 0.14 12.0 1.3 0.17 11.7 0.1 1.7 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Pkinase PF00069.25 RLN96652.1 - 1.1e-48 166.0 0.0 1.6e-48 165.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN96652.1 - 1.3e-44 152.4 0.0 2e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TMEM154 PF15102.6 RLN96652.1 - 0.0027 17.6 0.0 0.007 16.3 0.0 1.7 1 0 0 1 1 1 1 TMEM154 protein family DUF1180 PF06679.12 RLN96652.1 - 0.0029 18.0 0.1 0.0056 17.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Cytomega_TRL10 PF06084.11 RLN96652.1 - 0.0092 16.0 0.1 0.022 14.8 0.1 1.6 1 0 0 1 1 1 1 Cytomegalovirus TRL10 protein Herpes_gE PF02480.16 RLN96652.1 - 0.013 14.2 0.1 0.02 13.7 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Orf78 PF06024.12 RLN96652.1 - 0.019 15.2 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 RLN96652.1 - 0.02 15.8 0.0 0.046 14.6 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 RLN96652.1 - 0.035 14.0 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Rifin VMA21 PF09446.10 RLN96652.1 - 0.058 13.5 2.0 0.18 12.0 0.9 2.3 2 0 0 2 2 2 0 VMA21-like domain Amnionless PF14828.6 RLN96652.1 - 0.076 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Amnionless TMEM51 PF15345.6 RLN96652.1 - 0.11 12.3 0.3 0.18 11.7 0.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Haspin_kinase PF12330.8 RLN96652.1 - 0.13 11.1 0.0 0.27 10.1 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain AI-2E_transport PF01594.16 RLN96652.1 - 0.19 10.8 0.0 0.28 10.3 0.0 1.1 1 0 0 1 1 1 0 AI-2E family transporter SKG6 PF08693.10 RLN96652.1 - 0.22 10.9 2.3 0.6 9.6 2.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MiAMP1 PF09117.10 RLN96652.1 - 0.24 11.6 5.1 5.3 7.4 1.1 2.8 1 1 1 2 2 2 0 MiAMP1 Cpn10 PF00166.21 RLN96653.1 - 9.7e-29 99.3 0.0 1.1e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit GatD_N PF18195.1 RLN96653.1 - 0.033 13.5 0.0 2 7.8 0.0 2.4 1 1 1 2 2 2 0 GatD N-terminal domain Amidohydro_1 PF01979.20 RLN96654.1 - 1.1e-65 222.3 0.0 1.6e-65 221.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 RLN96654.1 - 1.1e-13 51.5 4.5 2.8e-09 37.0 0.1 2.1 1 1 0 2 2 2 2 Amidohydrolase family HA2 PF04408.23 RLN96655.1 - 3e-22 79.0 1.9 1.3e-21 76.9 0.0 3.0 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RLN96655.1 - 7.4e-12 45.5 0.0 1.6e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 RLN96655.1 - 4.3e-11 43.1 0.0 1.4e-10 41.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RLN96655.1 - 1.6e-07 31.2 0.1 3.8e-07 30.0 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RLN96655.1 - 1.5e-05 25.3 0.1 4.2e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 RLN96655.1 - 0.00019 20.8 0.0 0.00042 19.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 RLN96655.1 - 0.00055 19.7 0.0 0.0014 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RLN96655.1 - 0.0015 18.9 0.1 0.0036 17.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 RLN96655.1 - 0.0043 17.1 0.0 2.4 8.2 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 RLN96655.1 - 0.0044 16.1 0.0 0.0089 15.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 RLN96655.1 - 0.0055 17.2 0.0 0.018 15.6 0.0 1.9 1 0 0 1 1 1 1 ABC transporter Flavi_DEAD PF07652.14 RLN96655.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_14 PF13173.6 RLN96655.1 - 0.016 15.2 0.1 0.088 12.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RLN96655.1 - 0.03 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 RLN96655.1 - 0.03 13.7 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 RLN96655.1 - 0.043 13.3 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 RLN96655.1 - 0.046 13.9 1.8 0.16 12.1 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 RLN96655.1 - 0.052 13.9 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Rhodanese PF00581.20 RLN96655.1 - 0.078 13.5 0.0 0.24 11.9 0.0 1.8 1 0 0 1 1 1 0 Rhodanese-like domain SRP54 PF00448.22 RLN96655.1 - 0.12 12.0 0.2 0.29 10.8 0.2 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 RLN96655.1 - 0.12 12.9 0.1 0.12 12.9 0.1 2.3 2 1 0 2 2 1 0 AAA domain CENP-B_N PF04218.13 RLN96656.1 - 5.1e-12 45.2 0.9 8.1e-12 44.6 0.9 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc5 PF03221.16 RLN96656.1 - 1.2e-07 31.7 0.1 2.1e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.6 RLN96656.1 - 2.1e-05 24.2 0.2 0.00052 19.7 0.1 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 RLN96656.1 - 0.00029 20.8 0.1 0.00061 19.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 RLN96656.1 - 0.0017 18.4 0.0 0.026 14.7 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 RLN96656.1 - 0.016 15.2 0.0 0.056 13.5 0.0 2.0 1 0 0 1 1 1 0 Winged helix-turn helix BrkDBD PF09607.10 RLN96656.1 - 0.1 12.4 0.2 0.54 10.1 0.1 2.1 2 0 0 2 2 2 0 Brinker DNA-binding domain T2SSM PF04612.12 RLN96656.1 - 0.1 12.7 0.5 4.6 7.3 0.0 3.0 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein M EF-hand_7 PF13499.6 RLN96657.1 - 2e-37 127.4 10.7 6.4e-16 58.6 0.3 4.6 3 1 3 6 6 6 5 EF-hand domain pair EF-hand_1 PF00036.32 RLN96657.1 - 8.1e-37 122.0 18.1 1.9e-08 33.2 0.9 6.7 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.6 RLN96657.1 - 2.2e-31 105.1 9.5 1e-05 25.1 0.1 6.7 6 0 0 6 6 6 6 EF-hand domain EF-hand_8 PF13833.6 RLN96657.1 - 6.4e-24 83.6 18.6 1.2e-08 34.6 0.5 6.2 5 2 2 7 7 7 5 EF-hand domain pair EF-hand_5 PF13202.6 RLN96657.1 - 7e-23 79.1 15.5 2.2e-05 23.7 0.3 6.8 7 0 0 7 7 7 5 EF hand C2 PF00168.30 RLN96657.1 - 1e-16 61.1 0.0 2.6e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_9 PF14658.6 RLN96657.1 - 2.7e-12 46.8 0.6 0.0041 17.4 0.1 4.5 3 1 1 4 4 4 3 EF-hand domain EF-hand_4 PF12763.7 RLN96657.1 - 4.6e-08 32.9 3.2 0.33 10.9 0.1 4.2 3 1 1 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RLN96657.1 - 4.9e-06 26.8 0.0 0.58 10.5 0.0 3.3 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 RLN96657.1 - 0.036 14.2 0.2 2.3 8.4 0.0 2.6 2 0 0 2 2 2 0 Ca2+ insensitive EF hand DUF3872 PF12988.7 RLN96657.1 - 0.15 11.9 0.2 0.51 10.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3872) Peptidase_C48 PF02902.19 RLN96659.1 - 0.0013 18.6 0.3 0.0024 17.8 0.3 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Eryth_link_C PF16915.5 RLN96659.1 - 0.072 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Annelid erythrocruorin linker subunit C-terminus Arm PF00514.23 RLN96661.1 - 2.3e-09 37.0 20.9 0.46 10.6 0.0 10.3 9 0 0 9 9 9 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN96661.1 - 0.00022 21.7 5.7 0.68 10.5 0.2 6.1 5 0 0 5 5 5 1 HEAT-like repeat ParcG PF10274.9 RLN96661.1 - 0.026 14.6 1.1 0.074 13.2 1.1 1.7 1 0 0 1 1 1 0 Parkin co-regulated protein CRAL_TRIO PF00650.20 RLN96661.1 - 0.11 12.3 0.8 0.29 10.8 0.8 1.7 1 0 0 1 1 1 0 CRAL/TRIO domain DUF1279 PF06916.13 RLN96662.1 - 2.3e-14 53.7 2.1 1.3e-13 51.3 2.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) HECT PF00632.25 RLN96664.1 - 4e-53 180.9 0.0 5.1e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Methyltransf_25 PF13649.6 RLN96664.1 - 4.1e-12 46.6 0.1 3.3e-11 43.7 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN96664.1 - 5.8e-10 39.8 0.0 1.2e-09 38.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN96664.1 - 1.2e-09 38.7 0.0 2.5e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN96664.1 - 7.2e-09 35.7 0.0 1.3e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN96664.1 - 7.2e-07 29.1 0.0 3.8e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN96664.1 - 0.0025 17.4 0.0 0.03 13.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 RLN96664.1 - 0.08 12.4 0.0 1.5 8.2 0.0 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain ADH_zinc_N PF00107.26 RLN96664.1 - 0.18 11.8 0.0 0.52 10.3 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GAS PF13851.6 RLN96665.1 - 1.8e-68 229.9 23.8 1.8e-68 229.9 23.8 3.6 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding Med3 PF11593.8 RLN96666.1 - 1.2 8.3 8.7 1.4 8.0 8.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal GIDA_assoc PF13932.6 RLN96666.1 - 1.2 9.3 6.1 7.8 6.6 0.3 2.2 1 1 0 2 2 2 0 GidA associated domain Presenilin PF01080.17 RLN96666.1 - 4.5 5.9 5.3 5.9 5.5 5.3 1.1 1 0 0 1 1 1 0 Presenilin BSP_II PF05432.11 RLN96668.1 - 0.0056 16.4 37.1 0.0056 16.4 37.1 3.1 2 1 1 3 3 3 1 Bone sialoprotein II (BSP-II) Utp14 PF04615.13 RLN96668.1 - 0.028 13.0 62.6 0.036 12.7 62.6 1.0 1 0 0 1 1 1 0 Utp14 protein DUF3677 PF12432.8 RLN96669.1 - 3.4e-09 36.9 0.1 1.2e-08 35.1 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3677) DUF3037 PF11236.8 RLN96669.1 - 0.18 12.2 0.2 1.1 9.7 0.2 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) HECT PF00632.25 RLN96671.1 - 2.9e-20 73.0 0.0 1.4e-19 70.8 0.0 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Clathrin PF00637.20 RLN96672.1 - 5.7e-180 590.4 39.9 2.8e-29 101.8 1.0 7.7 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 RLN96672.1 - 2.1e-29 101.2 0.6 6.3e-29 99.7 0.6 1.9 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.20 RLN96672.1 - 5.9e-19 67.4 0.2 1.1e-06 28.6 0.0 5.8 5 0 0 5 5 5 3 Clathrin propeller repeat Clathrin-link PF09268.10 RLN96672.1 - 6.7e-06 25.4 0.2 2.1e-05 23.8 0.2 2.0 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_1 PF00515.28 RLN96672.1 - 0.0017 18.1 2.5 1.7 8.6 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN96672.1 - 0.0082 16.1 4.9 11 6.3 0.1 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN96672.1 - 0.009 16.8 1.7 1.5e+02 3.6 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN96672.1 - 0.021 15.0 0.4 1.1 9.5 0.1 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 RLN96672.1 - 0.037 14.1 8.8 1.9 8.8 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 RLN96672.1 - 0.057 13.9 1.0 14 6.3 0.4 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN96672.1 - 0.079 13.3 0.6 15 5.9 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat PSD2 PF07624.11 RLN96672.1 - 0.15 11.9 0.0 0.9 9.4 0.0 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) Isochorismatase PF00857.20 RLN96673.1 - 5.5e-05 23.4 0.0 0.069 13.3 0.0 2.5 3 0 0 3 3 3 2 Isochorismatase family Bax1-I PF01027.20 RLN96675.1 - 5.3e-05 23.1 6.6 0.00036 20.4 0.4 2.0 1 1 1 2 2 2 2 Inhibitor of apoptosis-promoting Bax1 CDC48_N PF02359.18 RLN96676.1 - 6.7e-22 77.5 2.0 1e-21 76.9 2.0 1.3 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain TORC_M PF12885.7 RLN96676.1 - 0.035 14.0 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain DNA_ligase_OB PF03120.16 RLN96676.1 - 0.16 11.9 1.7 1.4 8.8 1.3 2.1 1 1 1 2 2 2 0 NAD-dependent DNA ligase OB-fold domain Dus PF01207.17 RLN96677.1 - 3.4e-32 111.8 0.1 4e-16 59.0 0.2 3.7 2 2 1 3 3 3 3 Dihydrouridine synthase (Dus) zf-C2H2_jaz PF12171.8 RLN96677.1 - 0.00024 21.3 0.7 0.00024 21.3 0.7 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RLN96677.1 - 0.00042 20.6 0.7 0.00042 20.6 0.7 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 RLN96677.1 - 0.022 14.5 0.1 0.049 13.4 0.1 1.6 1 0 0 1 1 1 0 U1 zinc finger AKAP95 PF04988.12 RLN96677.1 - 0.034 14.4 0.1 0.066 13.4 0.1 1.4 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.7 RLN96677.1 - 0.073 13.4 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) EF-hand_7 PF13499.6 RLN96678.1 - 2e-25 89.0 3.2 1.3e-08 35.1 0.4 5.0 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 RLN96678.1 - 5.8e-22 75.5 11.9 0.00044 19.6 0.4 5.6 5 0 0 5 5 5 5 EF hand EF-hand_5 PF13202.6 RLN96678.1 - 1.3e-17 62.4 9.5 0.00034 20.0 0.0 5.4 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 RLN96678.1 - 2.3e-17 61.4 11.7 0.00074 19.3 0.2 5.8 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 RLN96678.1 - 6.9e-12 45.0 5.4 0.03 14.2 0.0 5.6 4 1 1 5 5 5 4 EF-hand domain pair EF-hand_9 PF14658.6 RLN96678.1 - 7.4e-05 23.0 1.5 0.14 12.5 0.0 4.2 4 0 0 4 4 4 1 EF-hand domain EF-hand_4 PF12763.7 RLN96678.1 - 0.00033 20.6 2.2 0.025 14.5 0.0 3.5 3 1 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand WD40 PF00400.32 RLN96678.1 - 0.00064 20.5 5.4 18 6.4 0.1 6.4 7 0 0 7 7 6 0 WD domain, G-beta repeat FYVE PF01363.21 RLN96678.1 - 0.013 15.7 13.3 0.033 14.3 13.3 1.7 1 0 0 1 1 1 0 FYVE zinc finger PriCT_1 PF08708.11 RLN96678.1 - 0.027 14.2 0.0 0.086 12.6 0.0 1.8 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) TerB PF05099.13 RLN96678.1 - 0.16 11.9 11.5 1.5 8.8 0.1 4.7 4 0 0 4 4 4 0 Tellurite resistance protein TerB FYVE_2 PF02318.16 RLN96678.1 - 1.1 9.5 6.6 3.1 8.0 6.6 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger PEP_mutase PF13714.6 RLN96679.1 - 2.3e-27 96.0 1.1 8.8e-24 84.3 1.7 2.2 1 1 1 2 2 2 2 Phosphoenolpyruvate phosphomutase ICL PF00463.21 RLN96679.1 - 9.7e-17 60.6 0.1 1.2e-16 60.3 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PreAtp-grasp PF18604.1 RLN96679.1 - 0.023 14.3 0.1 0.058 13.0 0.0 1.7 2 0 0 2 2 2 0 Pre ATP-grasp domain Pkinase PF00069.25 RLN96680.1 - 1.1e-65 221.7 0.0 1.4e-65 221.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN96680.1 - 7.8e-29 100.7 0.0 2e-28 99.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN96680.1 - 1.6e-06 27.7 0.0 2.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Bax1-I PF01027.20 RLN96680.1 - 6.3e-05 22.9 3.2 8.5e-05 22.5 3.2 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Kdo PF06293.14 RLN96680.1 - 0.00096 18.6 0.1 0.00096 18.6 0.1 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RLN96680.1 - 0.0036 16.3 0.1 0.007 15.4 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 RLN96680.1 - 0.02 13.7 0.6 0.074 11.8 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 RLN96680.1 - 0.082 12.5 0.1 0.082 12.5 0.1 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 RLN96680.1 - 0.09 11.8 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 RLN96680.1 - 0.095 12.6 1.6 0.28 11.1 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 RLN96680.1 - 0.095 11.6 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Dimer_Tnp_hAT PF05699.14 RLN96681.1 - 3.4e-15 55.6 0.1 9.6e-15 54.1 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DBD_Tnp_Hermes PF10683.9 RLN96681.1 - 0.014 15.0 0.1 0.051 13.3 0.0 1.9 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain DUF4371 PF14291.6 RLN96681.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4371) p450 PF00067.22 RLN96683.1 - 3.6e-16 59.0 0.0 4.5e-16 58.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 RLN96684.1 - 8.2e-75 252.3 0.0 1e-74 252.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ank PF00023.30 RLN96692.1 - 2.1e-15 56.4 1.9 0.0007 19.9 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 RLN96692.1 - 6.1e-14 52.4 0.1 1.1e-09 38.7 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN96692.1 - 8.1e-14 51.5 1.9 0.00029 21.1 0.0 4.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN96692.1 - 2.3e-12 45.9 1.0 4.7e-05 23.5 0.0 5.2 4 1 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 RLN96692.1 - 2.7e-11 43.8 0.3 4.9e-05 23.8 0.1 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) FYVE PF01363.21 RLN96692.1 - 0.0045 17.1 8.9 0.012 15.7 8.4 2.0 1 1 0 1 1 1 1 FYVE zinc finger IBR PF01485.21 RLN96692.1 - 0.027 14.7 3.3 0.027 14.7 3.3 1.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain SpoU_methylase PF00588.19 RLN96693.1 - 1.3e-09 38.3 0.0 6.8e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 SpoU rRNA Methylase family AhpC-TSA PF00578.21 RLN96693.1 - 0.0027 17.6 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Peptidase_C97 PF05903.14 RLN96694.1 - 1.4e-35 122.4 0.0 1.6e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain Peptidase_C69 PF03577.15 RLN96695.1 - 1.3e-43 149.5 0.2 2.1e-43 148.8 0.2 1.4 1 1 0 1 1 1 1 Peptidase family C69 DUF4440 PF14534.6 RLN96695.1 - 0.0098 16.3 0.1 0.028 14.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) UDPGT PF00201.18 RLN96696.1 - 1.2e-17 63.9 0.1 4.8e-17 61.9 0.0 1.7 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 RLN96696.1 - 4.8e-05 23.4 0.0 7.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Pkinase PF00069.25 RLN96697.1 - 5.7e-59 199.6 0.0 1.8e-30 106.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN96697.1 - 1.3e-32 113.1 0.0 8.4e-16 58.0 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Myb_DNA-bind_4 PF13837.6 RLN96697.1 - 1.5e-07 31.7 0.2 4.5e-07 30.2 0.2 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Kinase-like PF14531.6 RLN96697.1 - 7.4e-06 25.5 0.0 0.21 10.9 0.0 3.3 3 0 0 3 3 3 3 Kinase-like MADF_DNA_bdg PF10545.9 RLN96697.1 - 0.0013 19.0 0.4 0.0039 17.5 0.4 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Apo-VLDL-II PF05418.11 RLN96697.1 - 0.087 13.4 0.6 0.72 10.5 0.3 2.3 2 0 0 2 2 2 0 Apovitellenin I (Apo-VLDL-II) Phage_GPO PF05929.11 RLN96697.1 - 5.8 6.5 7.4 0.28 10.8 1.7 1.6 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase EF-hand_1 PF00036.32 RLN96698.1 - 8.8e-21 71.9 2.7 4.1e-05 22.8 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 RLN96698.1 - 4.3e-19 66.8 7.2 2.6e-05 23.8 0.1 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 RLN96698.1 - 3e-17 62.8 2.0 2.3e-07 31.1 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN96698.1 - 3e-16 58.1 0.5 0.00022 20.5 0.0 4.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RLN96698.1 - 9.6e-16 57.4 0.3 0.0088 15.9 0.0 4.4 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_10 PF14788.6 RLN96698.1 - 0.016 15.1 0.5 0.87 9.5 0.1 3.0 2 1 1 3 3 3 0 EF hand LCAT PF02450.15 RLN96699.1 - 5.5e-48 164.1 0.0 9.6e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 RLN96699.1 - 0.031 13.8 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF900 PF05990.12 RLN96699.1 - 0.053 13.0 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) BRE PF06113.12 RLN96699.1 - 0.13 11.0 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) Med26 PF08711.11 RLN96700.1 - 1.3e-09 37.9 0.9 2.7e-09 36.9 0.9 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain SAM_1 PF00536.30 RLN96700.1 - 1.1e-07 32.2 0.0 2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RLN96700.1 - 5.2e-05 23.3 0.1 0.00013 22.0 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Peptidase_M22 PF00814.25 RLN96701.1 - 1.9e-34 119.6 0.0 2.3e-34 119.3 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Esterase PF00756.20 RLN96702.1 - 9.3e-36 123.7 0.0 5.8e-33 114.6 0.0 2.1 1 1 1 2 2 2 2 Putative esterase Hydrolase_4 PF12146.8 RLN96702.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S8 PF00082.22 RLN96703.1 - 1.6e-33 116.3 0.0 4.5e-33 114.8 0.0 1.6 1 1 0 1 1 1 1 Subtilase family Ribosom_S12_S23 PF00164.25 RLN96704.1 - 2.6e-37 126.9 1.2 3.1e-37 126.7 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 RLN96704.1 - 0.0011 19.7 0.0 0.0016 19.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S12 Glyco_tran_28_C PF04101.16 RLN96704.1 - 0.076 13.0 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Proton_antipo_M PF00361.20 RLN96705.1 - 3e-68 230.2 36.6 4.1e-68 229.7 36.6 1.2 1 0 0 1 1 1 1 Proton-conducting membrane transporter Complex1_49kDa PF00346.19 RLN96706.1 - 1.1e-114 382.1 0.0 1.6e-114 381.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 RLN96706.1 - 0.00042 19.3 0.0 0.0013 17.7 0.0 1.9 2 0 0 2 2 2 1 Nickel-dependent hydrogenase Proton_antipo_M PF00361.20 RLN96707.1 - 6.3e-77 258.6 28.2 6.3e-77 258.6 28.2 2.2 2 1 1 3 3 3 1 Proton-conducting membrane transporter Oxidored_q5_N PF01059.17 RLN96707.1 - 0.00014 21.9 10.5 0.00014 21.9 10.5 5.0 3 2 1 5 5 5 1 NADH-ubiquinone oxidoreductase chain 4, amino terminus DUF3377 PF11857.8 RLN96707.1 - 0.68 9.9 3.1 1.6 8.7 0.5 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) NADHdh PF00146.21 RLN96708.1 - 1.8e-84 283.6 18.6 2.1e-84 283.3 18.6 1.0 1 0 0 1 1 1 1 NADH dehydrogenase TMEM132D_C PF15706.5 RLN96708.1 - 2 8.2 4.3 3 7.7 0.3 2.8 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Molybdopterin PF00384.22 RLN96709.1 - 2.9e-58 197.8 4.0 3.4e-38 131.7 1.6 2.9 1 1 1 2 2 2 2 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.9 RLN96709.1 - 2e-14 52.9 0.1 2e-14 52.9 0.1 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.6 RLN96709.1 - 1.5e-11 44.2 0.0 2.3e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 RLN96709.1 - 4e-06 26.7 0.2 4e-06 26.7 0.2 1.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 RLN96709.1 - 0.046 13.5 0.0 4.1 7.2 0.0 2.7 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 RLN96709.1 - 0.14 12.0 1.4 4 7.4 0.4 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Proton_antipo_M PF00361.20 RLN96710.1 - 1.2e-83 280.8 22.4 1.2e-83 280.8 22.4 2.7 3 1 0 3 3 3 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 RLN96710.1 - 9.5e-21 73.6 4.3 9.5e-21 73.6 4.3 3.3 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus NADH5_C PF06455.11 RLN96710.1 - 9.6e-20 70.9 15.9 9.6e-20 70.9 15.9 4.9 3 2 1 4 4 4 1 NADH dehydrogenase subunit 5 C-terminus Ribosomal_S8 PF00410.19 RLN96711.1 - 2.6e-34 117.9 3.2 2.9e-34 117.8 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 Pox_L3_FP4 PF03339.14 RLN96711.1 - 0.0044 16.1 0.7 0.005 15.9 0.7 1.1 1 0 0 1 1 1 1 Poxvirus L3/FP4 protein ICEA PF05315.11 RLN96711.1 - 0.034 13.6 2.7 0.037 13.5 2.7 1.0 1 0 0 1 1 1 0 ICEA Protein CENP-X PF09415.10 RLN96711.1 - 0.046 14.0 0.1 0.064 13.6 0.1 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Nucleoporin_N PF08801.11 RLN96711.1 - 0.071 11.8 0.8 0.084 11.6 0.8 1.1 1 0 0 1 1 1 0 Nup133 N terminal like pXO2-72 PF17443.2 RLN96711.1 - 0.2 11.9 0.3 0.2 11.9 0.3 2.4 1 1 1 2 2 2 0 Uncharacterized protein pXO2-72 Ribosomal_S14 PF00253.21 RLN96712.1 - 3.5e-19 68.3 0.2 5.3e-19 67.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e FN3_7 PF18447.1 RLN96712.1 - 0.066 13.5 1.8 0.081 13.2 1.8 1.2 1 0 0 1 1 1 0 Fibronectin type III domain COX3 PF00510.18 RLN96713.1 - 1.5e-86 290.4 27.4 1.7e-86 290.3 27.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III ATP-synt_A PF00119.20 RLN96714.1 - 4.4e-44 151.0 31.4 4.8e-44 150.8 31.4 1.0 1 0 0 1 1 1 1 ATP synthase A chain DUF2631 PF10939.8 RLN96714.1 - 1 9.3 3.5 1.1 9.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2631) Oxidored_q4 PF00507.19 RLN96715.1 - 3.8e-30 104.0 6.5 3.8e-30 104.0 6.5 1.5 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 MARVEL PF01284.23 RLN96715.1 - 0.0013 18.8 9.2 0.002 18.2 9.2 1.2 1 1 0 1 1 1 1 Membrane-associating domain DUF4293 PF14126.6 RLN96715.1 - 0.042 14.1 2.5 0.055 13.7 2.5 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) EI24 PF07264.11 RLN96715.1 - 0.06 13.6 8.6 0.079 13.2 8.6 1.2 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DHHC PF01529.20 RLN96715.1 - 3.2 7.9 10.4 8.8 6.4 10.4 1.7 1 1 0 1 1 1 0 DHHC palmitoyltransferase ATP-synt_ab PF00006.25 RLN96716.1 - 3.7e-63 213.0 0.0 8.8e-63 211.8 0.0 1.7 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 RLN96716.1 - 9.2e-45 152.0 1.8 1.5e-44 151.3 1.8 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 RLN96716.1 - 6.6e-11 42.6 1.3 1.5e-10 41.4 0.3 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 RLN96716.1 - 0.0058 16.8 0.2 0.091 12.9 0.2 2.4 1 1 1 2 2 2 1 HAS barrel domain TniB PF05621.11 RLN96716.1 - 0.075 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein ATP-synt_C PF00137.21 RLN96717.1 - 3.9e-12 46.3 11.3 4.6e-12 46.1 11.3 1.1 1 0 0 1 1 1 1 ATP synthase subunit C MFS_3 PF05977.13 RLN96717.1 - 0.14 10.5 2.7 0.16 10.3 2.7 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector Ribosomal_L14 PF00238.19 RLN96718.1 - 1e-30 106.3 2.2 1.2e-30 106.1 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RsgI_N PF12791.7 RLN96718.1 - 0.22 11.5 8.2 0.07 13.0 2.8 2.8 3 1 1 4 4 4 0 Anti-sigma factor N-terminus Ribosomal_S13 PF00416.22 RLN96719.1 - 9.7e-20 71.3 1.3 6.4e-18 65.4 1.3 2.1 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Ribosomal_L2_C PF03947.18 RLN96720.1 - 1.1e-51 174.3 0.6 1.7e-51 173.6 0.6 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 RLN96720.1 - 4.1e-23 81.1 1.8 1.3e-22 79.6 0.6 2.2 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Cnl2_NKP2 PF09447.10 RLN96720.1 - 0.019 15.1 0.0 0.056 13.6 0.0 1.8 1 0 0 1 1 1 0 Cnl2/NKP2 family protein Ribosomal_S19 PF00203.21 RLN96721.1 - 8.3e-20 70.5 0.8 1.1e-19 70.1 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L16 PF00252.18 RLN96722.1 - 1.1e-40 138.7 4.6 1.2e-40 138.6 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Biotin_lipoyl_2 PF13533.6 RLN96722.1 - 0.00052 19.8 0.1 0.00094 19.0 0.1 1.4 1 0 0 1 1 1 1 Biotin-lipoyl like tRNA-synt_2 PF00152.20 RLN96723.1 - 4e-19 68.8 0.0 5.4e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF659 PF04937.15 RLN96724.1 - 0.13 12.2 0.0 0.57 10.0 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF 659) MCM2_N PF12619.8 RLN96724.1 - 0.14 12.5 2.1 1.4 9.2 0.4 2.6 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 SPT6_acidic PF14632.6 RLN96724.1 - 5.6 7.6 6.4 0.5 11.0 0.2 2.3 2 0 0 2 2 2 0 Acidic N-terminal SPT6 RrnaAD PF00398.20 RLN96725.1 - 2.4e-44 151.4 0.0 3.2e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 RLN96725.1 - 1.6e-07 31.9 0.0 3.6e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN96725.1 - 1.6e-05 25.5 0.0 4e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN96725.1 - 6.6e-05 22.7 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 RLN96725.1 - 0.00019 21.5 0.0 0.0021 18.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN96725.1 - 0.00042 20.2 0.0 0.00068 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN96725.1 - 0.00062 19.4 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 RLN96725.1 - 0.0007 20.2 0.0 0.0016 19.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 RLN96725.1 - 0.0012 18.6 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_4 PF02390.17 RLN96725.1 - 0.003 17.0 0.0 0.0053 16.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_28 PF02636.17 RLN96725.1 - 0.0054 16.4 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase ESX-1_EspG PF14011.6 RLN96725.1 - 0.0055 16.4 0.5 0.0055 16.4 0.5 2.5 3 0 0 3 3 3 1 EspG family DREV PF05219.12 RLN96725.1 - 0.023 13.8 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Ldh_1_C PF02866.18 RLN96729.1 - 8.2e-49 165.7 0.3 1.5e-48 164.9 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 RLN96729.1 - 1.6e-43 148.1 0.3 2.4e-43 147.6 0.3 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 RLN96729.1 - 0.0051 16.1 0.3 0.17 11.2 0.1 2.5 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.19 RLN96729.1 - 0.0076 15.3 0.1 0.025 13.6 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 RLN96729.1 - 0.15 12.5 0.5 0.58 10.6 0.1 2.2 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Cation_ATPase_C PF00689.21 RLN96730.1 - 2.3e-36 125.2 1.3 2.3e-36 125.2 1.3 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 RLN96730.1 - 1.5e-30 106.1 8.5 6.7e-20 71.4 0.1 2.8 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 RLN96730.1 - 1.2e-19 70.2 0.0 3e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RLN96730.1 - 6.9e-17 62.4 2.6 8.8e-16 58.8 2.6 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 RLN96730.1 - 2.6e-05 24.1 0.0 0.00054 19.8 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 RLN96730.1 - 0.03 14.7 1.2 0.076 13.4 0.3 2.2 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase FliMN_C PF01052.20 RLN96730.1 - 0.15 12.1 0.1 0.39 10.8 0.1 1.8 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term Peptidase_M24 PF00557.24 RLN96735.1 - 1.7e-40 139.0 0.0 2.3e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Prenyltrans PF00432.21 RLN96736.1 - 1.2e-06 28.2 1.0 0.0055 16.4 0.1 2.1 2 0 0 2 2 2 2 Prenyltransferase and squalene oxidase repeat DIT1_PvcA PF05141.12 RLN96738.1 - 6.4e-64 216.1 0.1 7.3e-63 212.6 0.1 2.0 1 1 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein DIT1_PvcA PF05141.12 RLN96739.1 - 6.9e-55 186.5 0.0 1.2e-53 182.4 0.0 2.0 1 1 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein LAP1C PF05609.12 RLN96739.1 - 0.0031 16.7 0.0 0.0044 16.2 0.0 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) ABC_membrane PF00664.23 RLN96740.1 - 1.4e-53 182.3 3.3 2e-53 181.8 3.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region adh_short PF00106.25 RLN96740.1 - 3.8e-29 101.5 0.0 2.3e-28 99.0 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN96740.1 - 1.9e-16 60.4 0.1 4.2e-16 59.2 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN96740.1 - 7.5e-08 32.5 0.0 1.4e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 KR domain ABC_tran PF00005.27 RLN96740.1 - 0.00064 20.2 0.2 0.0012 19.4 0.2 1.5 1 0 0 1 1 1 1 ABC transporter ArsP_1 PF03773.13 RLN96740.1 - 0.0073 15.5 3.8 0.012 14.8 3.8 1.3 1 0 0 1 1 1 1 Predicted permease Epimerase PF01370.21 RLN96740.1 - 0.0092 15.5 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RsgA_GTPase PF03193.16 RLN96740.1 - 0.022 14.7 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 RLN96740.1 - 0.058 13.1 0.2 0.15 11.8 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PKD_channel PF08016.12 RLN96741.1 - 3e-29 101.9 0.6 4.1e-18 65.3 0.0 2.6 3 0 0 3 3 3 2 Polycystin cation channel TIL PF01826.17 RLN96741.1 - 0.042 14.1 8.6 0.087 13.1 8.6 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain ZYG-11_interact PF05884.12 RLN96743.1 - 0.026 14.0 0.8 0.033 13.6 0.8 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 FAM104 PF15434.6 RLN96743.1 - 0.05 14.2 4.5 0.066 13.8 3.8 1.7 1 1 0 1 1 1 0 Family 104 LCD1 PF09798.9 RLN96743.1 - 0.053 12.0 6.8 0.067 11.7 6.8 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF2347 PF09804.9 RLN96743.1 - 0.3 10.6 1.9 0.41 10.2 1.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) SlyX PF04102.12 RLN96743.1 - 0.75 10.5 5.3 0.33 11.6 2.7 1.9 2 0 0 2 2 2 0 SlyX Synaptobrevin PF00957.21 RLN96744.1 - 1.9e-15 56.4 0.7 3e-15 55.8 0.7 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 RLN96744.1 - 1.2e-09 38.1 0.0 2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Nsp1_C PF05064.13 RLN96744.1 - 0.016 15.0 0.6 0.04 13.7 0.4 1.8 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF3629 PF12302.8 RLN96745.1 - 0.024 14.1 0.3 0.04 13.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) DUF1664 PF07889.12 RLN96745.1 - 0.4 10.7 22.9 0.028 14.4 3.1 5.0 1 1 4 6 6 6 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 RLN96745.1 - 1.2 8.6 35.5 0.32 10.4 20.0 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 Fib_alpha PF08702.10 RLN96745.1 - 2.1 8.5 23.1 0.75 10.0 5.0 4.9 1 1 5 6 6 6 0 Fibrinogen alpha/beta chain family DUF4709 PF15821.5 RLN96745.1 - 3.5 8.0 11.2 1.5 9.1 0.8 4.0 3 2 1 4 4 4 0 Domain of unknown function (DUF4709) Glyco_transf_28 PF03033.20 RLN96746.1 - 9.5e-26 90.5 0.5 1.6e-19 70.3 0.2 3.5 2 1 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 RLN96746.1 - 1e-05 24.6 0.2 4.4e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 RLN96746.1 - 0.0023 18.3 0.0 0.016 15.6 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Gal_mutarotas_2 PF13802.6 RLN96746.1 - 0.013 15.9 0.1 0.053 13.9 0.1 2.2 2 0 0 2 2 2 0 Galactose mutarotase-like SIS_2 PF13580.6 RLN96746.1 - 0.016 15.3 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 SIS domain Glutaredoxin PF00462.24 RLN96747.1 - 1.6e-56 188.4 0.0 4.1e-17 62.1 0.0 3.7 3 0 0 3 3 3 3 Glutaredoxin Thioredoxin PF00085.20 RLN96747.1 - 4.1e-08 33.1 0.0 1.2e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin SH3BGR PF04908.15 RLN96747.1 - 5.2e-08 32.9 0.0 0.53 10.5 0.0 3.8 3 0 0 3 3 3 3 SH3-binding, glutamic acid-rich protein GST_N_3 PF13417.6 RLN96747.1 - 0.0012 19.2 0.0 1.2 9.6 0.0 3.3 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain ZinT PF09223.11 RLN96747.1 - 0.0039 17.1 0.0 10 5.9 0.0 3.3 3 0 0 3 3 3 1 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment CxC1 PF18802.1 RLN96747.1 - 0.011 15.9 0.0 10 6.3 0.0 3.2 3 0 0 3 3 3 0 CxC1 like cysteine cluster associated with KDZ transposases HyaE PF07449.11 RLN96747.1 - 0.03 14.3 0.2 0.27 11.2 0.1 2.7 4 0 0 4 4 4 0 Hydrogenase-1 expression protein HyaE Phosducin PF02114.16 RLN96747.1 - 0.11 11.4 0.0 0.22 10.5 0.0 1.5 1 0 0 1 1 1 0 Phosducin DUF2535 PF10751.9 RLN96747.1 - 0.12 12.9 0.0 1.3e+02 3.2 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2535) PPR PF01535.20 RLN96747.1 - 0.48 10.8 2.3 71 4.0 0.0 3.6 2 1 1 3 3 3 0 PPR repeat GTP_EFTU PF00009.27 RLN96748.1 - 1.3e-36 126.0 0.0 2e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 RLN96748.1 - 5.7e-20 71.7 0.1 1.2e-19 70.7 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 RLN96748.1 - 2.8e-06 27.4 0.0 0.0017 18.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase HBS1_N PF08938.10 RLN96748.1 - 3e-05 24.2 0.0 6.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 HBS1 N-terminus PhoLip_ATPase_C PF16212.5 RLN96750.1 - 6e-65 219.5 5.3 6e-65 219.5 5.3 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RLN96750.1 - 1.3e-20 72.9 0.4 2.7e-20 71.8 0.4 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RLN96750.1 - 4.9e-10 40.0 1.3 0.0023 18.3 1.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN96750.1 - 1.2e-08 34.9 0.0 4.7e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RLN96750.1 - 0.0028 17.2 0.0 0.0076 15.8 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RLN96750.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 RLN96750.1 - 0.079 13.3 0.0 4.2 7.7 0.0 2.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HIT PF01230.23 RLN96751.1 - 2.9e-16 60.0 0.6 5.8e-08 33.4 0.3 2.1 1 1 1 2 2 2 2 HIT domain DcpS_C PF11969.8 RLN96751.1 - 0.00021 21.8 0.1 0.15 12.5 0.0 2.1 1 1 1 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding LRR_4 PF12799.7 RLN96753.1 - 4.6e-20 71.4 13.3 5.4e-07 29.8 0.4 4.8 4 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN96753.1 - 3.4e-19 68.3 15.3 6.8e-06 25.8 1.2 4.5 3 1 0 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 RLN96753.1 - 9.9e-08 31.7 23.6 0.0075 15.8 1.4 4.8 3 2 2 5 5 5 4 Leucine-rich repeat LRR_6 PF13516.6 RLN96753.1 - 7.7e-06 25.6 13.9 0.16 12.1 0.1 6.5 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 RLN96753.1 - 0.0003 20.9 5.5 25 5.9 0.1 5.8 6 0 0 6 6 6 2 Leucine Rich Repeat Utp14 PF04615.13 RLN96753.1 - 0.088 11.4 66.8 0.14 10.7 66.8 1.2 1 0 0 1 1 1 0 Utp14 protein Kelch_3 PF13415.6 RLN96754.1 - 2.4e-30 104.2 7.2 2.7e-09 37.1 0.0 6.6 6 2 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN96754.1 - 4.6e-24 84.0 1.0 0.00073 19.5 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 RLN96754.1 - 8.7e-19 67.1 4.2 0.00039 20.6 0.0 6.1 5 1 1 6 6 6 4 Kelch motif Kelch_4 PF13418.6 RLN96754.1 - 1.3e-18 66.8 9.9 0.0015 18.5 0.0 5.9 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 RLN96754.1 - 7.5e-13 47.9 10.9 4.4e-05 23.3 0.1 5.7 6 0 0 6 6 5 4 Kelch motif Kelch_1 PF01344.25 RLN96754.1 - 5.6e-12 45.0 7.9 0.0028 17.2 0.0 6.1 6 1 0 6 6 6 3 Kelch motif TPR_11 PF13414.6 RLN96754.1 - 3.9e-06 26.4 0.1 0.0055 16.4 0.0 2.5 1 1 1 2 2 2 2 TPR repeat RAG2 PF03089.14 RLN96754.1 - 0.00011 21.3 0.1 0.089 11.8 0.0 3.4 3 2 0 3 3 3 2 Recombination activating protein 2 TPR_1 PF00515.28 RLN96754.1 - 0.00016 21.3 0.1 0.036 13.9 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN96754.1 - 0.0053 16.8 0.7 1.1 9.5 0.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN96754.1 - 0.039 14.8 1.4 6 8.0 0.1 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN96754.1 - 0.23 12.1 2.4 1.1 10.0 0.2 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat LRR_8 PF13855.6 RLN96755.1 - 1.1e-24 85.9 22.9 1.1e-08 34.7 1.4 4.6 2 1 4 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 RLN96755.1 - 5.1e-21 74.4 12.9 2.4e-05 24.6 0.0 5.7 2 1 6 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN96755.1 - 1.2e-13 49.6 24.9 0.53 11.0 0.3 9.5 9 1 0 9 9 9 6 Leucine Rich Repeat LRR_6 PF13516.6 RLN96755.1 - 1.2e-07 31.2 11.7 0.26 11.4 0.0 6.9 8 0 0 8 8 8 4 Leucine Rich repeat Gelsolin PF00626.22 RLN96757.1 - 6e-13 48.5 0.0 1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Gelsolin repeat VHP PF02209.19 RLN96757.1 - 4.5e-11 42.6 0.3 8.9e-11 41.7 0.3 1.5 1 0 0 1 1 1 1 Villin headpiece domain HhH-GPD PF00730.25 RLN96759.1 - 1.1e-19 70.9 0.0 2.1e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DCP1 PF06058.13 RLN96759.1 - 2.9e-09 36.9 0.1 5e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family HHH PF00633.23 RLN96759.1 - 4.8e-08 32.5 0.0 1.3e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif mRNA_decap_C PF16741.5 RLN96759.1 - 2.8e-06 26.5 0.1 4.8e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus HHH_8 PF14716.6 RLN96759.1 - 0.00075 19.8 0.0 0.0018 18.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.9 RLN96759.1 - 0.0024 18.1 7.1 0.004 17.5 7.1 1.4 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH_5 PF14520.6 RLN96759.1 - 0.0071 16.9 0.1 0.074 13.7 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain MSC PF09402.10 RLN96759.1 - 0.13 11.7 0.1 0.24 10.8 0.1 1.5 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain PFU PF09070.11 RLN96759.1 - 0.14 12.4 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) RVT_1 PF00078.27 RLN96759.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_E_B PF04042.16 RLN96760.1 - 2.2e-43 148.1 0.1 4e-43 147.2 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.8 RLN96760.1 - 0.0022 18.3 0.1 0.0067 16.7 0.1 1.8 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal DUF1654 PF07867.11 RLN96763.1 - 0.17 11.7 1.4 2.7 7.8 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1654) SAGA-Tad1 PF12767.7 RLN96766.1 - 0.24 11.1 4.5 0.38 10.4 4.5 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Uso1_p115_C PF04871.13 RLN96766.1 - 3.9 7.9 12.0 0.46 10.9 7.7 1.6 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Myb_DNA-binding PF00249.31 RLN96767.1 - 1.2e-11 44.6 6.9 0.0013 18.8 0.0 4.0 3 1 1 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN96767.1 - 9.1e-09 35.4 1.7 0.0079 16.4 0.0 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain DUF4780 PF16012.5 RLN96768.1 - 0.13 11.7 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4780) Peptidase_M50B PF13398.6 RLN96769.1 - 3.8e-53 180.1 20.6 3.8e-53 180.1 20.6 1.7 2 0 0 2 2 2 1 Peptidase M50B-like DUF1286 PF06939.11 RLN96769.1 - 0.036 14.3 0.8 0.036 14.3 0.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1286) Viral_DNA_bi PF02236.17 RLN96769.1 - 0.08 13.1 0.0 0.34 11.1 0.0 2.0 2 1 0 2 2 2 0 Viral DNA-binding protein, all alpha domain FtsL PF04999.13 RLN96769.1 - 0.39 10.7 0.1 0.39 10.7 0.1 2.3 3 0 0 3 3 3 0 Cell division protein FtsL Herpes_LMP1 PF05297.11 RLN96769.1 - 0.63 9.2 9.2 1.1 8.3 9.2 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF3267 PF11667.8 RLN96769.1 - 1 9.7 13.3 0.35 11.2 3.4 3.3 3 1 0 3 3 3 0 Putative zincin peptidase ELMO_CED12 PF04727.13 RLN96771.1 - 5.2e-29 101.6 0.0 1.9e-27 96.5 0.0 2.3 2 0 0 2 2 2 1 ELMO/CED-12 family PH PF00169.29 RLN96771.1 - 4.1e-18 65.8 0.0 1.7e-13 51.0 0.0 3.0 3 0 0 3 3 3 2 PH domain PH_11 PF15413.6 RLN96771.1 - 0.21 12.0 0.4 4.8 7.7 0.2 3.1 3 1 0 3 3 3 0 Pleckstrin homology domain TPR_12 PF13424.6 RLN96772.1 - 1.2e-19 70.3 4.6 0.0039 17.5 0.0 5.6 4 1 1 5 5 5 5 Tetratricopeptide repeat SAM_1 PF00536.30 RLN96772.1 - 1.3e-17 64.0 0.0 2.8e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RLN96772.1 - 2.7e-14 53.0 0.0 7.6e-14 51.6 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TPR_10 PF13374.6 RLN96772.1 - 6e-12 45.0 21.6 0.028 14.3 0.0 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat CHAT PF12770.7 RLN96772.1 - 9.7e-10 38.3 0.8 2.6e-09 36.9 0.8 1.7 1 0 0 1 1 1 1 CHAT domain NACHT PF05729.12 RLN96772.1 - 3.2e-06 27.2 0.0 7.3e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_17 PF13431.6 RLN96772.1 - 5.5e-05 23.3 0.1 0.48 10.9 0.1 4.1 5 0 0 5 5 4 2 Tetratricopeptide repeat AAA_25 PF13481.6 RLN96772.1 - 6.9e-05 22.5 0.0 0.00019 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RLN96772.1 - 0.0064 16.8 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RLN96772.1 - 0.0076 16.6 0.0 0.027 14.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 RLN96772.1 - 0.021 15.2 0.0 0.055 13.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SAM_4 PF18017.1 RLN96772.1 - 0.032 14.2 0.0 0.39 10.7 0.0 2.2 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) RhlB PF12300.8 RLN96772.1 - 2.5 8.2 12.4 1.4 9.1 9.4 2.1 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB PigN PF04987.14 RLN96774.1 - 1.7e-108 363.5 25.2 2.2e-108 363.1 25.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 RLN96774.1 - 3.6e-09 36.7 0.4 2.8e-07 30.4 0.4 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RLN96774.1 - 0.0015 18.0 0.1 0.0025 17.2 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Tetraspanin PF00335.20 RLN96774.1 - 1.2 8.8 4.4 5.8 6.6 0.0 3.3 3 0 0 3 3 3 0 Tetraspanin family Seryl_tRNA_N PF02403.22 RLN96775.1 - 9.7e-10 38.7 0.2 1.2e-09 38.4 0.2 1.0 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain MitMem_reg PF13012.6 RLN96776.1 - 3e-23 82.4 0.1 6.3e-23 81.3 0.0 1.5 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Allexi_40kDa PF05549.11 RLN96776.1 - 0.089 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein JAB PF01398.21 RLN96777.1 - 0.08 12.9 1.8 0.11 12.4 0.0 2.1 2 1 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RyR PF02026.16 RLN96779.1 - 1.1e-56 189.0 0.2 1.3e-27 95.8 0.0 3.6 3 0 0 3 3 3 2 RyR domain PKD_channel PF08016.12 RLN96779.1 - 3.4e-48 164.4 9.8 5.7e-48 163.6 9.8 1.4 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 RLN96779.1 - 8.8e-17 61.1 16.4 1.7e-16 60.2 16.4 1.4 1 0 0 1 1 1 1 Ion transport protein MKT1_C PF12246.8 RLN96779.1 - 0.022 14.0 0.2 0.045 13.0 0.2 1.4 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication EF-hand_1 PF00036.32 RLN96780.1 - 1.5e-16 58.6 2.4 6.9e-06 25.2 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 RLN96780.1 - 4.9e-14 51.0 3.8 4.1e-05 23.2 0.2 4.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 RLN96780.1 - 1.5e-12 47.8 0.9 1.2e-05 25.7 0.2 3.6 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN96780.1 - 4.8e-11 41.6 7.3 5.3e-06 25.7 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RLN96780.1 - 5.5e-09 35.7 1.3 0.00031 20.5 0.0 4.4 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RLN96780.1 - 5.8e-06 26.6 0.0 0.02 15.2 0.0 2.9 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Pkinase PF00069.25 RLN96781.1 - 4.6e-48 163.9 0.0 6.6e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN96781.1 - 7.8e-42 143.3 0.0 1.2e-41 142.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_6 PF13516.6 RLN96781.1 - 0.025 14.6 0.3 0.07 13.2 0.3 1.8 1 0 0 1 1 1 0 Leucine Rich repeat Kdo PF06293.14 RLN96781.1 - 0.18 11.1 0.1 0.31 10.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 RLN96782.1 - 4.8e-15 55.9 1.2 1.1e-05 26.0 0.1 4.6 4 1 1 5 5 5 2 Ankyrin repeats (3 copies) Ion_trans PF00520.31 RLN96782.1 - 1.3e-14 54.0 17.4 2.4e-14 53.2 17.4 1.4 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 RLN96782.1 - 2.2e-11 43.1 20.6 3e-06 26.2 14.5 2.2 1 1 1 2 2 2 2 Polycystin cation channel Ank_3 PF13606.6 RLN96782.1 - 2.3e-11 42.8 1.9 0.0015 18.9 0.1 4.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 RLN96782.1 - 9.7e-10 38.5 0.1 0.0021 18.3 0.0 4.4 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN96782.1 - 2.9e-09 36.9 3.9 0.014 15.8 0.2 4.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 RLN96782.1 - 2.5e-06 27.9 0.1 0.074 13.7 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) FHA PF00498.26 RLN96784.1 - 1.6e-08 34.8 0.0 2.9e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 RLN96784.1 - 0.11 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 FHA domain LRR_8 PF13855.6 RLN96785.1 - 1.6e-11 43.8 4.8 6.9e-06 25.7 0.2 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 RLN96785.1 - 2.3e-07 31.0 4.8 0.0031 17.9 0.9 4.0 3 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN96785.1 - 3e-05 24.0 0.0 4.2 8.3 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 RLN96785.1 - 0.0017 18.3 9.8 3 8.1 0.0 5.1 5 0 0 5 5 5 2 Leucine Rich repeat DUF4381 PF14316.6 RLN96785.1 - 0.0089 16.3 0.1 0.02 15.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) Pentapeptide_4 PF13599.6 RLN96785.1 - 0.035 14.3 0.3 1.2 9.4 0.1 2.3 1 1 2 3 3 3 0 Pentapeptide repeats (9 copies) TraT PF05818.12 RLN96785.1 - 8.4 6.0 6.3 24 4.6 6.3 1.7 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein GCP_N_terminal PF17681.1 RLN96786.1 - 9.5e-48 163.4 0.0 1.3e-47 163.0 0.0 1.1 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 RLN96787.1 - 2.4e-32 112.7 3.0 2.9e-32 112.4 3.0 1.1 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Amidohydro_1 PF01979.20 RLN96788.1 - 3.9e-71 240.2 2.5 5.7e-71 239.6 2.5 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 RLN96788.1 - 6.3e-53 178.2 6.8 6.7e-53 178.2 4.3 2.2 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 RLN96788.1 - 1.5e-38 130.8 0.0 3e-38 129.8 0.0 1.5 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 RLN96788.1 - 7e-10 39.1 0.7 2.2e-09 37.5 0.1 2.3 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_3 PF07969.11 RLN96788.1 - 4.7e-06 26.3 0.5 0.0025 17.4 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase family AAA_23 PF13476.6 RLN96789.1 - 1e-19 71.9 1.0 1e-19 71.9 1.0 5.3 2 2 1 3 3 3 1 AAA domain SMC_N PF02463.19 RLN96789.1 - 2.8e-12 46.6 13.8 5e-11 42.5 12.4 3.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 RLN96789.1 - 9.7e-09 35.4 7.3 9.7e-09 35.4 7.3 2.8 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 RLN96789.1 - 8.4e-05 22.2 0.0 0.00022 20.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 RLN96789.1 - 0.00025 21.0 0.1 0.00025 21.0 0.1 2.2 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN96789.1 - 0.35 11.2 0.0 0.35 11.2 0.0 3.3 4 2 1 5 5 5 0 AAA ATPase domain ADH_N PF08240.12 RLN96793.1 - 1.9e-27 95.3 0.8 3.8e-27 94.3 0.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN96793.1 - 3.5e-24 85.2 0.8 5.1e-24 84.7 0.8 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN96793.1 - 5.6e-05 24.2 0.2 9.1e-05 23.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 RLN96793.1 - 0.02 14.3 0.1 0.031 13.7 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 RLN96793.1 - 0.084 12.2 1.0 0.12 11.7 0.2 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.21 RLN96793.1 - 0.15 11.5 0.1 0.22 11.0 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TTC5_OB PF16669.5 RLN96793.1 - 0.17 11.5 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain ADH_N PF08240.12 RLN96794.1 - 5e-28 97.2 1.3 5e-28 97.2 1.3 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN96794.1 - 1.7e-23 83.0 0.5 2.6e-23 82.4 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN96794.1 - 0.00072 20.6 0.2 0.0012 19.9 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 RLN96794.1 - 0.027 13.9 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Methyltransf_15 PF09445.10 RLN96794.1 - 0.044 13.3 0.1 0.082 12.5 0.1 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Viral_Beta_CD PF04530.12 RLN96794.1 - 0.074 13.4 0.9 0.074 13.4 0.9 1.9 1 1 1 2 2 2 0 Viral Beta C/D like family AlaDh_PNT_C PF01262.21 RLN96794.1 - 0.084 12.2 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PS_pyruv_trans PF04230.13 RLN96794.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase DUF4523 PF15023.6 RLN96796.1 - 0.012 15.5 1.3 0.42 10.4 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4523) Ino80_Iec3 PF14612.6 RLN96796.1 - 0.079 13.6 5.8 0.13 13.0 5.5 1.4 1 1 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling Acyl-CoA_dh_2 PF08028.11 RLN96797.1 - 0.027 14.8 2.8 0.059 13.7 2.8 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain RVT_1 PF00078.27 RLN96798.1 - 0.00042 19.9 0.0 0.0015 18.1 0.0 1.8 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 RLN96798.1 - 0.013 16.2 1.6 0.032 14.9 1.6 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Sdh5 PF03937.16 RLN96799.1 - 0.069 13.1 0.0 3.8 7.6 0.0 2.6 3 0 0 3 3 3 0 Flavinator of succinate dehydrogenase Frag1 PF10277.9 RLN96800.1 - 2e-05 24.2 8.4 3.2e-05 23.6 8.4 1.3 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family BioY PF02632.14 RLN96800.1 - 0.011 15.7 9.1 0.019 15.0 6.4 2.3 1 1 2 3 3 3 0 BioY family ESSS PF10183.9 RLN96800.1 - 0.29 11.4 1.1 0.47 10.7 0.2 1.7 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) cobW PF02492.19 RLN96801.1 - 3.7e-31 108.1 0.0 7e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Carn_acyltransf PF00755.20 RLN96801.1 - 2e-14 53.1 0.4 2e-14 53.1 0.4 1.6 2 0 0 2 2 2 1 Choline/Carnitine o-acyltransferase MMR_HSR1 PF01926.23 RLN96801.1 - 0.01 15.9 0.0 0.039 14.0 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Suf PF05843.14 RLN96801.1 - 0.053 13.5 7.5 0.091 12.7 6.5 1.8 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) AAA_16 PF13191.6 RLN96801.1 - 0.29 11.5 0.0 0.29 11.5 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.6 RLN96801.1 - 0.41 11.1 0.0 0.41 11.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain SAGA-Tad1 PF12767.7 RLN96801.1 - 0.46 10.2 10.3 1.1 8.9 10.3 1.6 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Methyltransf_31 PF13847.6 RLN96802.1 - 0.0079 16.0 0.0 0.0089 15.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN96802.1 - 0.015 16.0 0.0 0.052 14.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 RLN96802.1 - 0.024 15.3 0.0 0.04 14.6 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain zf-CCHC PF00098.23 RLN96806.1 - 0.00025 21.0 1.6 0.00035 20.5 1.6 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 RLN96806.1 - 0.16 11.8 0.9 0.23 11.2 0.9 1.3 1 0 0 1 1 1 0 Zinc knuckle Arf PF00025.21 RLN96807.1 - 1e-45 155.3 0.9 1e-20 73.9 0.0 3.0 3 0 0 3 3 3 3 ADP-ribosylation factor family SRPRB PF09439.10 RLN96807.1 - 5.9e-06 25.8 0.1 0.069 12.6 0.0 2.2 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RLN96807.1 - 0.0038 16.4 0.1 0.74 8.9 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit AAA_16 PF13191.6 RLN96807.1 - 0.019 15.4 0.1 0.033 14.6 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 RLN96807.1 - 0.026 13.5 0.0 0.06 12.3 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Gtr1_RagA PF04670.12 RLN96807.1 - 0.064 12.6 0.0 8.9 5.6 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Roc PF08477.13 RLN96807.1 - 0.064 13.5 0.2 0.35 11.1 0.2 2.3 2 2 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase 6PF2K PF01591.18 RLN96807.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase NACHT PF05729.12 RLN96807.1 - 0.13 12.1 0.4 0.39 10.6 0.1 1.8 2 0 0 2 2 2 0 NACHT domain CAAD PF14159.6 RLN96807.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Ras PF00071.22 RLN96807.1 - 0.18 11.4 0.0 2.5 7.7 0.0 2.1 2 0 0 2 2 2 0 Ras family Apyrase PF06079.11 RLN96808.1 - 2.1e-56 191.3 0.0 2.4e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Apyrase YhzD PF14120.6 RLN96808.1 - 0.068 13.3 0.2 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 YhzD-like protein AlgF PF11182.8 RLN96808.1 - 0.13 12.0 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF DUF1674 PF07896.12 RLN96809.1 - 3.5e-10 40.2 3.9 7.7e-10 39.1 3.9 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) KdpC PF02669.15 RLN96809.1 - 0.097 12.5 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 K+-transporting ATPase, c chain DUF1394 PF07159.12 RLN96810.1 - 1.4e-05 24.5 0.8 1.4e-05 24.5 0.8 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1394) WASH-7_N PF14745.6 RLN96810.1 - 0.00063 18.4 0.5 0.00081 18.0 0.5 1.2 1 0 0 1 1 1 1 WASH complex subunit 7, N-terminal RPAP2_Rtr1 PF04181.13 RLN96810.1 - 0.75 10.2 5.0 41 4.6 3.8 2.8 2 1 0 2 2 2 0 Rtr1/RPAP2 family FragX_IP PF05994.11 RLN96811.1 - 1.1e-86 291.7 4.4 2e-64 218.1 3.2 2.2 2 0 0 2 2 2 2 Cytoplasmic Fragile-X interacting family UQ_con PF00179.26 RLN96812.1 - 3.1e-20 72.3 0.0 4.5e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UQ_con PF00179.26 RLN96813.1 - 2.3e-21 75.9 0.0 2.8e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 RLN96813.1 - 0.1 12.9 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 RWD domain DNA_pol_B PF00136.21 RLN96814.1 - 5.6e-104 348.4 0.0 8.7e-104 347.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 RLN96814.1 - 1.5e-43 148.7 2.0 3.5e-43 147.5 2.0 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 RLN96814.1 - 2.5e-28 99.2 0.0 4.7e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 RLN96814.1 - 1.9e-16 59.9 4.4 6.7e-16 58.1 4.4 2.0 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 RLN96814.1 - 0.0025 16.7 0.0 0.0046 15.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral TB2_DP1_HVA22 PF03134.19 RLN96815.1 - 1.7e-30 104.7 8.0 2.6e-30 104.2 8.0 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family RCC1 PF00415.18 RLN96816.1 - 3.4e-74 245.3 13.2 1e-14 54.9 0.1 7.8 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 RLN96816.1 - 1.9e-55 188.6 0.0 3.5e-55 187.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DEAD PF00270.29 RLN96816.1 - 2.4e-45 154.4 0.1 7.1e-45 152.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase RCC1_2 PF13540.6 RLN96816.1 - 1e-32 111.2 39.4 3.6e-08 33.0 0.3 8.8 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Helicase_C PF00271.31 RLN96816.1 - 2.9e-27 95.2 0.0 1.3e-26 93.1 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SPRY PF00622.28 RLN96816.1 - 2.3e-20 72.9 0.1 7e-20 71.3 0.1 1.9 1 0 0 1 1 1 1 SPRY domain Laminin_G_3 PF13385.6 RLN96816.1 - 3.8e-09 36.9 0.0 1.3e-06 28.7 0.0 3.9 3 1 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily UBA PF00627.31 RLN96816.1 - 0.00022 21.1 0.0 0.00063 19.6 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DUF29 PF01724.16 RLN96816.1 - 0.057 13.7 0.6 0.17 12.1 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF29 SWI2_SNF2 PF18766.1 RLN96816.1 - 0.068 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Trypsin_2 PF13365.6 RLN96817.1 - 7.6e-15 56.1 1.3 2.4e-14 54.5 0.2 2.2 2 0 0 2 2 2 1 Trypsin-like peptidase domain TPR_17 PF13431.6 RLN96818.1 - 0.00025 21.2 0.0 0.084 13.3 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF2069 PF09842.9 RLN96818.1 - 0.0023 18.1 2.3 0.0023 18.1 2.3 2.4 3 0 0 3 3 3 1 Predicted membrane protein (DUF2069) TPR_9 PF13371.6 RLN96818.1 - 0.015 15.5 0.6 0.21 11.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat YfhO PF09586.10 RLN96818.1 - 0.038 12.2 0.4 0.084 11.1 0.4 1.5 1 0 0 1 1 1 0 Bacterial membrane protein YfhO RNA_pol PF00940.19 RLN96819.1 - 1e-45 156.3 0.5 7.6e-45 153.5 0.5 1.9 1 1 0 1 1 1 1 DNA-dependent RNA polymerase ADH_N PF08240.12 RLN96820.1 - 1.1e-27 96.1 0.7 1.1e-27 96.1 0.7 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RLN96820.1 - 2.1e-24 86.0 0.5 3.1e-24 85.4 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN96820.1 - 9.7e-05 23.4 0.2 0.00016 22.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 RLN96820.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Viral_Beta_CD PF04530.12 RLN96820.1 - 0.066 13.5 0.6 0.066 13.5 0.6 2.0 2 1 1 3 3 3 0 Viral Beta C/D like family Epimerase PF01370.21 RLN96820.1 - 0.15 11.5 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NRDE-2 PF08424.10 RLN96822.1 - 2.5e-44 151.7 9.9 2e-32 112.6 5.6 3.3 2 1 0 2 2 2 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 RLN96822.1 - 2.4e-06 27.9 7.1 0.14 13.0 0.0 6.2 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN96822.1 - 0.0051 17.3 2.5 1.8 9.1 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat LRR_4 PF12799.7 RLN96823.1 - 0.11 12.9 1.9 0.23 12.0 0.8 2.1 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) Pribosyltran PF00156.27 RLN96824.1 - 1.8e-08 34.0 0.1 2.7e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain eIF3_N PF09440.10 RLN96828.1 - 0.1 13.1 6.7 0.089 13.2 4.8 1.9 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain Spec3 PF15795.5 RLN96828.1 - 0.13 12.9 0.2 0.53 10.9 0.0 2.0 2 0 0 2 2 2 0 Ectodermal ciliogenesis protein Allexi_40kDa PF05549.11 RLN96828.1 - 0.65 9.5 2.8 1.6 8.2 1.9 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein Arm PF00514.23 RLN96829.1 - 2.2e-20 71.9 1.6 1.5e-05 24.9 0.0 6.1 6 1 0 6 6 6 5 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 RLN96829.1 - 1e-05 25.5 0.1 0.014 15.4 0.0 3.4 2 1 1 3 3 3 2 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 RLN96829.1 - 0.00024 21.4 7.6 0.012 15.9 1.0 3.8 1 1 4 5 5 5 3 HEAT repeats HEAT_EZ PF13513.6 RLN96829.1 - 0.00034 21.0 6.2 0.081 13.5 0.0 5.2 4 2 3 7 7 7 1 HEAT-like repeat HEAT_PBS PF03130.16 RLN96829.1 - 0.0032 18.0 10.4 51 5.0 0.2 6.4 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat POTRA_TamA_1 PF17243.2 RLN96829.1 - 0.11 12.6 0.3 0.41 10.8 0.1 1.9 2 0 0 2 2 2 0 POTRA domain TamA domain 1 DEAD PF00270.29 RLN96831.1 - 7.1e-46 156.2 0.0 3.5e-45 153.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN96831.1 - 3.6e-33 114.2 0.2 8.7e-33 113.0 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 RLN96831.1 - 0.015 14.6 0.1 0.022 14.0 0.1 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 RLN96831.1 - 0.091 12.8 0.0 0.31 11.0 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PTPS PF01242.19 RLN96832.1 - 3.5e-12 46.4 0.1 6.2e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase zf-BED PF02892.15 RLN96832.1 - 0.053 13.5 3.0 0.067 13.2 1.5 1.9 2 0 0 2 2 2 0 BED zinc finger IRK_C PF17655.1 RLN96833.1 - 1.3e-27 96.5 1.1 2e-12 47.1 0.0 3.3 3 0 0 3 3 3 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 RLN96833.1 - 1.1e-13 51.2 23.9 4.8e-06 26.4 8.2 4.0 2 2 1 3 3 3 3 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 RLN96833.1 - 1.5e-13 50.5 22.9 1.6e-07 31.2 7.9 2.4 2 0 0 2 2 2 2 Ion channel Hydrolase_like PF13242.6 RLN96834.1 - 1.2e-11 44.5 0.0 1.7e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 RLN96834.1 - 0.065 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase TruB_C_2 PF16198.5 RLN96834.1 - 0.084 13.0 0.2 0.84 9.8 0.1 2.2 2 0 0 2 2 2 0 tRNA pseudouridylate synthase B C-terminal domain Hydrolase_6 PF13344.6 RLN96834.1 - 0.12 12.5 0.1 0.29 11.3 0.0 1.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase RRM_1 PF00076.22 RLN96835.1 - 1.5e-05 24.7 0.0 2.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_16 PF05301.11 RLN96836.1 - 1.9e-42 145.0 0.0 2.8e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_1 PF00583.25 RLN96836.1 - 0.0052 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF4427 PF14468.6 RLN96836.1 - 0.0053 16.8 0.0 0.0081 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4427) Acetyltransf_10 PF13673.7 RLN96836.1 - 0.015 15.2 0.0 0.11 12.4 0.0 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RLN96836.1 - 0.034 14.6 0.0 0.068 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-RING_11 PF17123.5 RLN96837.1 - 7.7e-11 41.5 1.9 7.7e-11 41.5 1.9 2.5 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_2 PF13639.6 RLN96837.1 - 1.6e-10 41.1 3.9 1.6e-10 41.1 3.9 4.2 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN96837.1 - 1.5e-07 31.1 3.3 1.5e-07 31.1 3.3 5.2 5 2 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN96837.1 - 5.4e-07 29.4 3.2 5.4e-07 29.4 3.2 4.8 3 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN96837.1 - 9.2e-06 25.5 3.6 9.2e-06 25.5 3.6 4.4 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RLN96837.1 - 1.3e-05 25.0 2.0 1.3e-05 25.0 2.0 4.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN96837.1 - 2.8e-05 24.3 1.9 2.8e-05 24.3 1.9 3.5 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 RLN96837.1 - 0.00049 20.1 0.7 0.00049 20.1 0.7 2.6 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 RLN96837.1 - 0.0011 19.0 0.3 0.0011 19.0 0.3 4.5 4 2 0 4 4 4 1 RING-type zinc-finger PHD PF00628.29 RLN96837.1 - 0.01 15.7 1.7 0.01 15.7 1.7 4.2 4 2 0 4 4 4 0 PHD-finger zf-C3HC4_4 PF15227.6 RLN96837.1 - 0.01 16.0 2.4 0.01 16.0 2.4 4.7 4 2 0 4 4 4 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 RLN96837.1 - 0.011 15.5 2.7 0.011 15.5 2.7 3.9 4 1 0 4 4 4 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 RLN96837.1 - 0.017 14.7 2.4 0.017 14.7 2.4 3.2 4 1 0 4 4 3 0 Zinc-ribbon, C4HC2 type zinc-ribbons_6 PF07191.12 RLN96837.1 - 0.082 12.9 20.8 0.083 12.9 3.9 3.7 3 1 1 4 4 4 0 zinc-ribbons DZR PF12773.7 RLN96837.1 - 3.1 7.9 30.2 2.1 8.4 0.5 3.8 2 1 1 3 3 3 0 Double zinc ribbon YacG PF03884.14 RLN96837.1 - 4.1 7.2 15.1 17 5.2 2.7 3.7 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG Ank_4 PF13637.6 RLN96838.1 - 1.4e-14 54.3 3.4 6.8e-06 26.5 0.2 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN96838.1 - 1.4e-13 51.2 1.0 2.4e-05 24.8 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN96838.1 - 1.7e-13 49.4 1.9 0.19 12.4 0.1 5.9 5 0 0 5 5 5 4 Ankyrin repeat Aida_C2 PF14186.6 RLN96838.1 - 3.7e-12 46.1 0.0 1.6e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal adhesion Ank_5 PF13857.6 RLN96838.1 - 1e-10 41.7 2.2 0.0067 16.7 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) PH PF00169.29 RLN96838.1 - 4.4e-06 27.2 0.0 1.1e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 PH domain Ank PF00023.30 RLN96838.1 - 0.00073 19.9 5.8 2.4 8.8 0.0 4.6 4 1 0 4 4 4 2 Ankyrin repeat IQ PF00612.27 RLN96838.1 - 0.18 11.7 0.1 0.18 11.7 0.1 12.2 13 1 0 13 13 13 0 IQ calmodulin-binding motif Cation_efflux PF01545.21 RLN96839.1 - 5.1e-48 163.4 0.5 8.4e-48 162.7 0.5 1.4 1 0 0 1 1 1 1 Cation efflux family Plant_vir_prot PF01307.17 RLN96839.1 - 0.02 15.1 1.0 0.056 13.7 1.0 1.7 1 0 0 1 1 1 0 Plant viral movement protein Zip PF02535.22 RLN96839.1 - 0.32 10.2 16.9 0.029 13.6 12.3 1.7 2 1 0 2 2 2 0 ZIP Zinc transporter PAS_9 PF13426.7 RLN96840.1 - 0.56 10.5 0.0 0.56 10.5 0.0 4.4 3 1 0 4 4 4 0 PAS domain SAS-6_N PF16531.5 RLN96841.1 - 6.7e-28 97.1 2.4 9.4e-28 96.6 2.4 1.2 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal Pkinase PF00069.25 RLN96842.1 - 2.2e-57 194.5 0.1 6.7e-57 192.8 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN96842.1 - 6.8e-22 78.0 0.1 1.8e-21 76.6 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN96842.1 - 0.00062 19.2 0.0 0.0035 16.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 RLN96842.1 - 0.12 11.7 0.3 0.2 11.0 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 RLN96842.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 ABC1 family YrbL-PhoP_reg PF10707.9 RLN96842.1 - 0.18 11.3 0.1 0.33 10.4 0.1 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 RLN96842.1 - 0.29 9.8 1.4 0.43 9.3 0.4 1.7 2 0 0 2 2 2 0 Fungal protein kinase Trm112p PF03966.16 RLN96843.1 - 5.4e-16 58.9 0.0 8.1e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Trm112p-like protein DNAPolymera_Pol PF11590.8 RLN96843.1 - 0.11 12.3 0.3 0.23 11.4 0.3 1.5 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol DUF4646 PF15496.6 RLN96843.1 - 0.15 12.7 0.0 0.18 12.4 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4646) DUF948 PF06103.11 RLN96845.1 - 0.027 14.7 2.2 2.3 8.5 0.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Spore_YhaL PF14147.6 RLN96845.1 - 0.077 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Sporulation protein YhaL DUF4510 PF14971.6 RLN96846.1 - 0.084 13.2 4.8 0.12 12.8 4.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4510) DUF4464 PF14713.6 RLN96846.1 - 0.37 10.3 4.0 0.48 10.0 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4464) FAM76 PF16046.5 RLN96846.1 - 6.1 6.1 8.4 8.6 5.6 8.4 1.3 1 1 0 1 1 1 0 FAM76 protein MULE PF10551.9 RLN96847.1 - 8.5e-16 58.2 3.0 1.1e-15 57.8 1.2 2.2 2 0 0 2 2 2 1 MULE transposase domain Peptidase_C48 PF02902.19 RLN96847.1 - 1.2e-10 41.6 0.0 3.1e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DDE_Tnp_ISL3 PF01610.17 RLN96847.1 - 0.0052 16.5 0.2 0.0052 16.5 0.2 2.1 2 0 0 2 2 2 1 Transposase SWIM PF04434.17 RLN96847.1 - 0.0054 16.4 1.6 0.0064 16.1 0.1 1.9 2 0 0 2 2 2 1 SWIM zinc finger Pkinase PF00069.25 RLN96848.1 - 2.2e-05 24.0 0.0 3.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Myb_DNA-binding PF00249.31 RLN96849.1 - 2e-08 34.3 0.1 2e-08 34.3 0.1 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN96849.1 - 0.0087 16.3 0.1 0.016 15.5 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Glyco_trans_1_4 PF13692.6 RLN96850.1 - 1.1e-07 32.3 0.0 9.1e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 RLN96850.1 - 1.8e-07 30.9 0.0 1.2e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 RLN96850.1 - 5.1e-07 29.8 0.2 1.1e-06 28.7 0.2 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 RLN96850.1 - 1.9e-06 28.4 5.7 1.9e-06 28.4 5.7 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 RLN96850.1 - 0.015 15.7 0.0 0.049 14.0 0.0 1.8 1 1 1 2 2 2 0 Glycosyl transferases group 1 Aldo_ket_red PF00248.21 RLN96851.1 - 1.6e-49 168.7 0.0 2e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2357 PF09823.9 RLN96851.1 - 0.15 11.3 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) Abhydrolase_2 PF02230.16 RLN96852.1 - 1.8e-34 119.5 0.0 1.8e-26 93.3 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 RLN96852.1 - 8e-08 31.8 1.9 0.0024 17.2 0.1 2.9 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 RLN96852.1 - 4.7e-07 29.5 0.9 1.6e-06 27.7 0.0 2.1 1 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 RLN96852.1 - 0.001 19.0 0.2 0.054 13.3 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN96852.1 - 0.002 18.7 8.0 0.011 16.3 2.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 RLN96852.1 - 0.0042 16.9 0.0 0.0062 16.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 RLN96852.1 - 0.0091 16.0 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Cutinase DLH PF01738.18 RLN96852.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 RLN96852.1 - 0.014 15.0 0.7 0.062 12.9 0.4 2.1 1 1 0 2 2 2 0 alpha/beta hydrolase fold FSH1 PF03959.13 RLN96852.1 - 0.025 14.2 0.0 0.67 9.6 0.1 2.2 1 1 1 2 2 2 0 Serine hydrolase (FSH1) Abhydro_lipase PF04083.16 RLN96852.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region LIP PF03583.14 RLN96852.1 - 0.15 11.3 0.2 3.2 7.0 0.0 2.2 1 1 1 2 2 2 0 Secretory lipase Abhydrolase_2 PF02230.16 RLN96853.1 - 3.5e-35 121.8 0.0 5.8e-22 78.6 0.0 2.0 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 RLN96853.1 - 1.4e-05 24.7 0.0 2.4e-05 23.9 0.0 1.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 RLN96853.1 - 3.9e-05 23.1 0.1 8.7e-05 21.9 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 RLN96853.1 - 0.0016 18.1 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 RLN96853.1 - 0.005 16.5 0.0 1.7 8.3 0.0 2.2 1 1 1 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 RLN96853.1 - 0.12 12.9 0.9 2 9.0 0.7 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family Aldo_ket_red PF00248.21 RLN96854.1 - 3.5e-137 456.4 0.0 5.5e-68 229.3 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Pro_sub2 PF18513.1 RLN96854.1 - 0.013 15.7 0.0 0.81 9.9 0.0 2.3 2 0 0 2 2 2 0 Prodomain subtilisin 2 Rtt106_N PF18215.1 RLN96854.1 - 0.2 11.4 0.2 6.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Histone chaperone Rtt106 N-terminal domain Agenet PF05641.12 RLN96855.1 - 0.02 15.4 0.1 1.2 9.6 0.0 2.6 2 0 0 2 2 2 0 Agenet domain SARAF PF06682.12 RLN96855.1 - 0.35 10.5 5.3 0.094 12.4 1.3 1.8 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis PET117 PF15786.5 RLN96855.1 - 1.2 9.5 6.4 1.7 9.0 0.0 2.5 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial Nha1_C PF08619.10 RLN96855.1 - 6.2 5.9 19.6 8.1 5.5 11.3 2.2 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus AMP-binding PF00501.28 RLN96857.1 - 8.8e-85 284.8 0.0 1e-84 284.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN96857.1 - 0.0014 19.6 0.0 0.0031 18.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF5115 PF17142.4 RLN96857.1 - 0.18 11.4 0.1 0.45 10.1 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5115) Kinesin PF00225.23 RLN96858.1 - 1e-11 44.4 0.0 6.9e-11 41.7 0.0 2.4 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RLN96858.1 - 0.063 13.2 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Microtubule binding KH_1 PF00013.29 RLN96859.1 - 9.6e-74 243.2 8.5 1.5e-09 37.6 0.0 11.2 11 0 0 11 11 11 9 KH domain KH_2 PF07650.17 RLN96859.1 - 7e-15 54.6 9.9 0.57 10.0 0.0 8.1 7 0 0 7 7 7 6 KH domain KH_4 PF13083.6 RLN96859.1 - 5.1e-13 48.7 3.8 1.2 9.1 0.0 7.8 7 0 0 7 7 7 5 KH domain SLS PF14611.6 RLN96859.1 - 1.3e-12 48.1 20.8 0.00073 19.4 0.2 8.6 4 3 4 8 8 8 4 Mitochondrial inner-membrane-bound regulator KH_5 PF13184.6 RLN96859.1 - 6.4e-06 26.2 7.3 0.69 10.0 0.1 6.7 7 0 0 7 7 7 2 NusA-like KH domain KAsynt_C_assoc PF16197.5 RLN96859.1 - 0.034 14.6 3.1 0.16 12.5 0.1 3.6 4 0 0 4 4 4 0 Ketoacyl-synthetase C-terminal extension UPF0184 PF03670.13 RLN96859.1 - 0.17 12.3 2.6 12 6.4 0.0 4.6 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0184) Dmrt1 PF12374.8 RLN96859.1 - 0.95 10.0 3.6 4.4 7.8 3.6 2.2 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 MFS_1 PF07690.16 RLN96860.1 - 2.2e-33 115.7 26.9 3e-33 115.2 26.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 RLN96860.1 - 0.00046 19.6 5.1 0.00046 19.6 5.1 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF3464 PF11947.8 RLN96860.1 - 5.9 6.6 5.3 2.1 8.1 1.9 2.0 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 MFS_1 PF07690.16 RLN96861.1 - 1.8e-33 116.0 26.9 2.2e-33 115.7 26.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 RLN96861.1 - 0.00037 19.9 5.1 0.00037 19.9 5.1 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF3464 PF11947.8 RLN96861.1 - 4.7 6.9 5.3 1.9 8.3 1.9 2.1 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 MFS_1 PF07690.16 RLN96862.1 - 2.9e-30 105.4 22.2 2.9e-30 105.4 22.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 RLN96863.1 - 1e-30 106.9 27.1 1.4e-30 106.4 27.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ABC_trans_CmpB PF06541.11 RLN96863.1 - 0.051 13.8 18.4 2 8.6 0.1 3.4 2 1 1 3 3 3 0 Putative ABC-transporter type IV MFS_1 PF07690.16 RLN96864.1 - 4e-29 101.6 29.7 5.3e-29 101.2 29.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 RLN96864.1 - 2.3 7.4 22.1 0.17 11.1 5.6 2.1 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 RLN96865.1 - 1e-31 110.2 32.6 1.4e-31 109.7 32.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily EI24 PF07264.11 RLN96866.1 - 1.8e-23 83.7 6.3 2.8e-23 83.1 6.3 1.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) HEAT_2 PF13646.6 RLN96869.1 - 1.8e-17 63.5 14.9 0.0011 19.3 0.0 8.6 6 2 5 11 11 11 5 HEAT repeats HEAT_EZ PF13513.6 RLN96869.1 - 1.3e-14 54.3 22.7 9e-05 22.9 0.4 10.8 9 2 3 12 12 12 3 HEAT-like repeat HEAT PF02985.22 RLN96869.1 - 2e-13 49.4 28.0 5.6e-05 23.0 0.1 13.2 15 0 0 15 15 14 2 HEAT repeat IBN_N PF03810.19 RLN96869.1 - 1.3e-11 44.2 1.7 3.7e-07 29.9 0.5 3.1 2 0 0 2 2 2 2 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 RLN96869.1 - 3.7e-07 30.7 0.0 0.0093 16.5 0.0 4.4 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 RLN96869.1 - 8.8e-07 29.1 4.9 0.00024 21.2 0.0 5.3 7 0 0 7 7 6 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 RLN96869.1 - 4e-05 23.4 1.0 1.7 8.4 0.0 5.4 6 1 1 7 7 7 2 rRNA processing/ribosome biogenesis MMS19_C PF12460.8 RLN96869.1 - 0.0015 17.8 0.2 0.054 12.6 0.3 2.8 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 RLN96869.1 - 0.0017 18.3 1.6 2.5 8.0 0.0 5.1 5 2 1 7 7 7 1 Domain of unknown function (DUF3385) CTD_bind PF04818.13 RLN96869.1 - 0.003 18.3 1.7 2.6 9.0 0.0 5.1 5 1 1 6 6 3 1 RNA polymerase II-binding domain. Tti2 PF10521.9 RLN96869.1 - 0.013 15.0 0.0 0.11 12.0 0.0 2.5 2 1 1 3 3 3 0 Tti2 family Importin_rep_4 PF18808.1 RLN96869.1 - 0.039 14.2 0.1 0.039 14.2 0.1 3.9 3 2 1 4 4 4 0 Importin repeat Adaptin_N PF01602.20 RLN96869.1 - 0.042 12.4 4.3 6.2 5.2 0.1 4.0 3 1 0 4 4 4 0 Adaptin N terminal region ParcG PF10274.9 RLN96869.1 - 0.086 13.0 0.8 6.8 6.8 0.0 4.0 5 1 1 6 6 5 0 Parkin co-regulated protein Arm PF00514.23 RLN96869.1 - 0.11 12.6 2.3 3.3 7.9 0.0 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF4611 PF15387.6 RLN96869.1 - 1.5 9.1 9.3 21 5.4 0.2 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) DUF3752 PF12572.8 RLN96870.1 - 1.7e-11 44.8 4.1 1.7e-11 44.8 4.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) TPR_1 PF00515.28 RLN96871.1 - 1.4e-08 34.2 4.0 0.00018 21.2 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN96871.1 - 6.7e-08 32.1 6.5 0.00022 21.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN96871.1 - 8.6e-05 22.6 1.2 8.6e-05 22.6 1.2 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN96871.1 - 0.00046 20.4 11.4 0.046 14.0 0.2 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN96871.1 - 0.0031 18.2 7.6 0.019 15.8 0.4 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN96871.1 - 0.0052 16.7 4.0 1.7 8.8 0.1 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat DUF3526 PF12040.8 RLN96871.1 - 0.0099 16.4 0.4 0.0099 16.4 0.4 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3526) Fis1_TPR_C PF14853.6 RLN96871.1 - 0.016 15.3 0.2 0.18 11.9 0.2 2.3 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 RLN96871.1 - 0.017 15.6 1.5 0.017 15.6 1.5 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 RLN96871.1 - 0.03 14.7 1.2 5.8 7.5 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN96871.1 - 0.12 12.6 2.9 0.1 12.9 1.1 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 2TM PF13239.6 RLN96871.1 - 0.14 12.4 0.0 0.14 12.4 0.0 1.7 2 0 0 2 2 1 0 2TM domain TPR_16 PF13432.6 RLN96871.1 - 0.59 10.8 9.4 7.1 7.4 0.8 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Matrilin_ccoil PF10393.9 RLN96871.1 - 1.4 8.9 0.0 1.4 8.9 0.0 3.7 5 0 0 5 5 5 0 Trimeric coiled-coil oligomerisation domain of matrilin PAE PF03283.13 RLN96872.1 - 6.2e-11 42.0 1.4 2e-10 40.3 1.4 1.7 1 1 0 1 1 1 1 Pectinacetylesterase Glyco_hydro81C PF17652.1 RLN96873.1 - 7.7e-114 380.6 2.5 1.1e-113 380.1 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 RLN96873.1 - 3.3e-51 174.4 2.9 5.5e-51 173.6 2.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain CENP-T_C PF15511.6 RLN96874.1 - 1.7e-08 34.5 0.1 2.1e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 RLN96874.1 - 0.00019 21.7 0.1 0.00025 21.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 RLN96874.1 - 0.0003 20.9 0.1 0.00042 20.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 RLN96874.1 - 0.004 17.4 0.0 0.0067 16.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 RLN96874.1 - 0.0046 17.3 0.2 0.0052 17.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 RLN96874.1 - 0.027 14.5 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 RLN96874.1 - 0.053 13.5 0.1 0.079 13.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 RLN96874.1 - 0.18 11.6 0.1 0.22 11.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) AAA_16 PF13191.6 RLN96875.1 - 6.2e-15 56.0 0.1 3.9e-14 53.4 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.29 RLN96875.1 - 3.9e-09 37.0 0.0 2.9e-08 34.2 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN96875.1 - 1.5e-07 31.7 0.1 7.6e-07 29.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_lid_10 PF17872.1 RLN96875.1 - 1.5e-05 25.0 0.1 4e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_30 PF13604.6 RLN96875.1 - 0.00069 19.4 0.2 0.0088 15.8 0.0 2.7 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 RLN96875.1 - 0.0025 18.2 0.0 0.031 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 RLN96875.1 - 0.012 15.3 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 RLN96875.1 - 0.013 14.7 0.0 0.026 13.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 RLN96875.1 - 0.016 15.7 0.0 0.12 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 RLN96875.1 - 0.031 14.2 0.0 0.095 12.6 0.0 1.8 1 0 0 1 1 1 0 NTPase PIF1 PF05970.14 RLN96875.1 - 0.07 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase ABC_tran PF00005.27 RLN96875.1 - 0.074 13.6 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 RLN96875.1 - 0.084 12.8 0.1 0.28 11.1 0.1 2.0 1 1 0 1 1 1 0 NACHT domain TsaE PF02367.17 RLN96875.1 - 0.095 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_32 PF13654.6 RLN96875.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Histone PF00125.24 RLN96876.1 - 5e-32 111.0 0.5 5.5e-32 110.9 0.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 RLN96876.1 - 0.00018 22.1 2.1 0.00021 21.9 2.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Mannosyl_trans3 PF11051.8 RLN96877.1 - 2e-34 119.2 0.0 7e-34 117.4 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.8 RLN96878.1 - 4.4e-29 101.7 0.0 4.4e-28 98.4 0.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative SLC35F PF06027.12 RLN96880.1 - 2.7e-09 36.9 8.3 3.1e-09 36.8 8.3 1.0 1 0 0 1 1 1 1 Solute carrier family 35 UAA PF08449.11 RLN96880.1 - 3.7e-05 23.1 2.8 4.2e-05 22.9 2.8 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 RLN96880.1 - 0.00017 21.8 7.0 0.00021 21.5 7.0 1.1 1 0 0 1 1 1 1 EamA-like transporter family TPT PF03151.16 RLN96880.1 - 0.0098 15.3 0.4 0.014 14.7 0.4 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family PLAC8 PF04749.17 RLN96881.1 - 2.7e-37 127.7 35.6 2.5e-18 66.9 18.8 2.4 2 0 0 2 2 2 2 PLAC8 family PLAC8 PF04749.17 RLN96882.1 - 3.7e-20 72.8 23.1 4.7e-20 72.4 23.1 1.1 1 0 0 1 1 1 1 PLAC8 family P5-ATPase PF12409.8 RLN96882.1 - 0.016 15.3 0.9 0.03 14.4 0.9 1.4 1 0 0 1 1 1 0 P5-type ATPase cation transporter Mito_carr PF00153.27 RLN96885.1 - 2.2e-55 184.6 5.9 7.3e-20 70.7 0.4 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 RLN96885.1 - 0.018 14.2 2.7 0.24 10.5 0.3 2.4 1 1 0 2 2 2 0 Gammaproteobacterial serine protease Oxidored_FMN PF00724.20 RLN96886.1 - 8.7e-80 268.5 0.0 9.9e-80 268.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1080 PF06439.11 RLN96887.1 - 0.18 11.9 0.0 0.2 11.7 0.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) Oxidored_FMN PF00724.20 RLN96888.1 - 5.9e-81 272.4 0.0 9e-81 271.8 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Peptidase_S8 PF00082.22 RLN96890.1 - 4.7e-39 134.4 8.7 4.7e-39 134.4 8.7 2.1 2 1 0 2 2 2 1 Subtilase family DUF3668 PF12416.8 RLN96893.1 - 9.1e-20 71.4 0.0 8.1e-19 68.3 0.0 2.4 2 0 0 2 2 2 1 Cep120 protein Dimer_Tnp_hAT PF05699.14 RLN96894.1 - 7.8e-06 25.6 0.0 9.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TAXi_N PF14543.6 RLN96895.1 - 0.067 13.4 1.1 0.17 12.1 1.1 1.6 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal PGA2 PF07543.12 RLN96895.1 - 0.69 9.9 8.4 0.3 11.0 0.6 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 HLH PF00010.26 RLN96902.1 - 0.027 14.4 2.3 0.053 13.5 2.3 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain LCD1 PF09798.9 RLN96902.1 - 0.029 12.9 0.0 0.052 12.1 0.0 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein MerR-DNA-bind PF09278.11 RLN96902.1 - 0.18 12.4 0.2 0.18 12.4 0.2 2.5 2 0 0 2 2 2 0 MerR, DNA binding DUF702 PF05142.12 RLN96902.1 - 0.68 10.4 2.5 67 3.9 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF702) DUF4576 PF15144.6 RLN96903.1 - 0.03 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) PRCC PF10253.9 RLN96904.1 - 0.51 11.1 6.1 0.13 13.1 3.1 1.5 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Herpes_BLLF1 PF05109.13 RLN96904.1 - 0.82 7.6 27.2 1.3 6.9 27.2 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) CDC27 PF09507.10 RLN96904.1 - 3.3 7.0 10.1 4.4 6.6 10.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Glyco_hydro_5_C PF18564.1 RLN96907.1 - 9.3e-17 61.4 0.4 2.2e-16 60.2 0.4 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain DUF1697 PF08002.11 RLN96907.1 - 0.15 12.6 0.1 0.33 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) FAD_binding_3 PF01494.19 RLN96908.1 - 1e-16 61.1 0.7 3.4e-14 52.9 0.7 3.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 RLN96908.1 - 1.1e-05 25.5 0.0 3.9e-05 23.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RLN96908.1 - 2.3e-05 24.2 0.0 5.3e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RLN96908.1 - 0.00076 18.8 0.2 0.0056 16.0 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RLN96908.1 - 0.0049 17.4 0.0 0.021 15.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RLN96908.1 - 0.0051 15.9 0.0 1 8.3 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein ApbA PF02558.16 RLN96908.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 RLN96908.1 - 0.018 14.1 0.0 0.042 12.9 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 RLN96908.1 - 0.064 12.5 0.1 0.87 8.8 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RLN96908.1 - 0.068 11.9 0.1 0.32 9.6 0.1 1.9 1 1 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 RLN96908.1 - 0.18 12.0 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Peptidase_S8 PF00082.22 RLN96909.1 - 6.3e-28 97.9 0.1 7.8e-28 97.6 0.1 1.1 1 0 0 1 1 1 1 Subtilase family SCAB-Ig PF16709.5 RLN96910.1 - 1.7e-05 24.8 0.0 4.4e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Ig domain of plant-specific actin-binding protein HAP1_N PF04849.13 RLN96910.1 - 0.039 13.2 2.9 0.063 12.5 2.9 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Baculo_PEP_C PF04513.12 RLN96910.1 - 0.15 12.1 0.4 0.27 11.3 0.4 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HMMR_N PF15905.5 RLN96910.1 - 1.2 8.6 9.0 0.14 11.6 1.4 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal FHA PF00498.26 RLN96911.1 - 3.1e-19 69.1 0.0 1.5e-18 66.9 0.0 2.2 2 0 0 2 2 2 1 FHA domain WD40 PF00400.32 RLN96911.1 - 8.9e-18 64.3 18.0 5.9e-06 26.9 0.3 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Yop-YscD_cpl PF16697.5 RLN96911.1 - 1.3e-12 47.8 0.0 6.2e-12 45.7 0.0 2.2 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain ANAPC4_WD40 PF12894.7 RLN96911.1 - 1.4e-07 31.7 0.0 0.5 10.7 0.0 4.7 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1018 PF06252.12 RLN96911.1 - 0.39 11.7 6.5 0.82 10.7 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) PPP4R2 PF09184.11 RLN96911.1 - 1 8.9 12.7 2.2 7.8 12.7 1.4 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 RLN96911.1 - 3 7.5 19.2 6.4 6.4 19.2 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SRP-alpha_N PF04086.13 RLN96911.1 - 6.2 6.7 15.9 0.24 11.3 10.0 1.6 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Diphthamide_syn PF01866.17 RLN96912.1 - 6.5e-94 314.8 0.0 1e-93 314.2 0.0 1.3 1 0 0 1 1 1 1 Putative diphthamide synthesis protein MOZART1 PF12554.8 RLN96912.1 - 1.4e-19 69.5 0.2 3.1e-19 68.5 0.2 1.5 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DUF1240 PF06836.12 RLN96913.1 - 0.019 15.5 3.4 2.2 8.9 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) zf-MYND PF01753.18 RLN96914.1 - 1.3e-11 44.3 13.7 1.9e-11 43.8 13.7 1.2 1 0 0 1 1 1 1 MYND finger GAGA PF09237.11 RLN96914.1 - 1.3 8.8 4.5 3.1 7.7 4.5 1.7 1 1 0 1 1 1 0 GAGA factor Glutenin_hmw PF03157.13 RLN96914.1 - 2.9 6.2 5.4 2.6 6.4 0.5 2.0 2 0 0 2 2 2 0 High molecular weight glutenin subunit ALG3 PF05208.13 RLN96915.1 - 2.5e-125 418.6 28.3 3.5e-125 418.2 28.3 1.2 1 0 0 1 1 1 1 ALG3 protein adh_short PF00106.25 RLN96916.1 - 1.7e-37 128.8 0.3 2.2e-37 128.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN96916.1 - 8.7e-28 97.4 0.0 1.2e-27 97.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN96916.1 - 4.2e-05 23.5 0.1 7.1e-05 22.8 0.1 1.3 1 1 0 1 1 1 1 KR domain WD40 PF00400.32 RLN96917.1 - 3.4e-12 46.7 0.1 4.9e-09 36.7 0.0 2.7 2 1 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN96917.1 - 0.00024 21.3 0.0 0.00099 19.4 0.0 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain HemX PF04375.14 RLN96917.1 - 0.00074 18.9 3.8 0.00089 18.6 3.8 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase SpoIIIAH PF12685.7 RLN96917.1 - 0.0025 17.7 0.2 0.0027 17.6 0.2 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein Ge1_WD40 PF16529.5 RLN96917.1 - 0.024 13.6 0.0 0.036 13.0 0.0 1.3 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PepSY_TM PF03929.16 RLN96917.1 - 0.025 14.2 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM region PAP_PilO PF06864.12 RLN96917.1 - 0.031 13.1 1.3 0.038 12.8 1.3 1.3 1 0 0 1 1 1 0 Pilin accessory protein (PilO) PEX11 PF05648.14 RLN96917.1 - 0.042 13.3 0.5 0.073 12.5 0.5 1.4 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DEPP PF15343.6 RLN96917.1 - 0.082 13.0 1.8 0.11 12.5 1.8 1.1 1 0 0 1 1 1 0 Decidual protein induced by progesterone family LapA_dom PF06305.11 RLN96917.1 - 0.15 11.9 3.2 0.16 11.8 1.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain FTZ PF03867.14 RLN96917.1 - 0.17 11.4 1.6 0.23 11.0 1.6 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region AAA_23 PF13476.6 RLN96919.1 - 0.0073 16.8 2.0 0.0073 16.8 2.0 3.2 1 1 1 2 2 2 1 AAA domain HTH_1 PF00126.27 RLN96919.1 - 1.5 8.9 5.6 1.5 8.8 0.1 3.3 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family DUF2703 PF10865.8 RLN96919.1 - 1.7 8.9 11.9 6.4 7.0 0.3 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF2703) Spc42p PF11544.8 RLN96919.1 - 5 7.2 19.5 0.22 11.5 0.2 5.3 4 1 0 4 4 4 0 Spindle pole body component Spc42p Pellino PF04710.14 RLN96920.1 - 1.5e-44 152.3 0.1 3.6e-22 78.6 0.1 5.3 4 1 1 5 5 5 4 Pellino zf-RING_2 PF13639.6 RLN96920.1 - 0.022 15.1 10.7 0.053 13.9 0.4 2.9 3 0 0 3 3 3 0 Ring finger domain zf-RING_5 PF14634.6 RLN96920.1 - 0.054 13.5 3.5 5 7.2 0.2 2.7 2 0 0 2 2 2 0 zinc-RING finger domain zf-rbx1 PF12678.7 RLN96920.1 - 0.79 10.1 6.3 0.2 12.0 0.5 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 RLN96920.1 - 1.1 9.2 9.6 3.6 7.5 0.6 3.2 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 RLN96920.1 - 4.4 7.2 11.4 1.5 8.7 0.2 3.4 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RNA_pol_Rpb2_6 PF00562.28 RLN96921.1 - 1.2e-113 380.2 0.8 3.1e-113 378.8 0.8 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 RLN96921.1 - 4.5e-37 127.5 0.1 7.4e-37 126.8 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 RLN96921.1 - 1.2e-28 99.1 0.0 3.3e-28 97.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 RLN96921.1 - 9.2e-23 80.5 0.6 2.4e-22 79.1 0.6 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 RLN96921.1 - 8.2e-17 61.5 0.0 1.5e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 RLN96921.1 - 5.9e-12 45.4 0.0 1.2e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain zf-B_box PF00643.24 RLN96921.1 - 6.9 6.9 5.6 42 4.4 0.8 2.5 2 0 0 2 2 2 0 B-box zinc finger Kinesin PF00225.23 RLN96922.1 - 9e-105 350.3 6.8 3.1e-60 203.9 0.1 2.6 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 RLN96922.1 - 2.8e-26 92.2 0.0 7.1e-26 90.9 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding STIMATE PF12400.8 RLN96923.1 - 1.3e-15 58.1 1.1 1.5e-15 57.8 1.1 1.1 1 0 0 1 1 1 1 STIMATE family Peptidase_C1 PF00112.23 RLN96924.1 - 6e-90 301.1 18.7 5.2e-54 183.6 2.1 2.3 2 0 0 2 2 2 2 Papain family cysteine protease Aldo_ket_red PF00248.21 RLN96925.1 - 4e-41 141.1 0.0 8.1e-39 133.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family His_Phos_1 PF00300.22 RLN96926.1 - 1.4e-17 64.0 0.0 2.4e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PH PF00169.29 RLN96926.1 - 0.0059 17.1 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 PH domain Rubis-subs-bind PF09273.11 RLN96927.1 - 9.4e-24 84.5 5.9 9.4e-24 84.5 5.9 2.1 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.28 RLN96927.1 - 2.9e-07 31.0 0.2 8.4e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 SET domain MMR_HSR1 PF01926.23 RLN96928.1 - 3.1e-16 59.5 0.3 3.2e-15 56.2 0.3 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN96928.1 - 4.6e-08 32.7 0.0 8.3e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 RLN96928.1 - 0.0021 17.1 0.0 0.0036 16.3 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 RLN96928.1 - 0.022 14.8 0.0 0.034 14.2 0.0 1.4 1 1 0 1 1 1 0 Dynamin family AAA_18 PF13238.6 RLN96928.1 - 0.024 15.2 0.0 0.034 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RLN96928.1 - 0.035 14.6 0.0 0.063 13.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.10 RLN96928.1 - 0.065 12.7 0.1 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Vac_Fusion PF02346.16 RLN96928.1 - 0.094 12.3 0.6 0.51 10.0 0.0 2.2 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 GTP_EFTU PF00009.27 RLN96928.1 - 0.12 11.9 0.7 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 RLN96928.1 - 0.14 11.3 0.1 0.21 10.7 0.1 1.5 1 1 0 1 1 1 0 NB-ARC domain Peptidase_S10 PF00450.22 RLN96929.1 - 8.6e-78 262.6 1.2 9.7e-78 262.4 1.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Ferritin-like PF12902.7 RLN96929.1 - 0.17 11.7 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Ferritin-like RRM_1 PF00076.22 RLN96932.1 - 2.7e-10 39.9 0.4 1.9e-09 37.2 0.4 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN96932.1 - 0.0029 17.7 0.1 0.0056 16.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif ING PF12998.7 RLN96933.1 - 0.016 15.8 1.2 0.016 15.8 1.2 1.9 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding LXG PF04740.12 RLN96933.1 - 0.03 14.0 6.8 0.19 11.4 6.8 2.0 1 1 0 1 1 1 0 LXG domain of WXG superfamily AAA_35 PF14516.6 RLN96933.1 - 0.072 11.9 0.3 0.3 9.9 0.2 1.8 2 0 0 2 2 2 0 AAA-like domain KELK PF15796.5 RLN96933.1 - 0.084 13.3 1.7 0.19 12.2 0.3 2.3 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FCH PF00611.23 RLN96933.1 - 0.15 12.4 0.1 0.15 12.4 0.1 2.7 4 0 0 4 4 4 0 Fes/CIP4, and EFC/F-BAR homology domain Fez1 PF06818.15 RLN96933.1 - 2.9 8.3 9.9 3.1 8.2 8.0 1.9 1 1 1 2 2 2 0 Fez1 DUF1690 PF07956.11 RLN96933.1 - 5.8 7.3 13.1 8.7 6.8 3.9 3.2 1 1 2 3 3 3 0 Protein of Unknown function (DUF1690) Pex2_Pex12 PF04757.14 RLN96934.1 - 5.8e-37 127.4 4.1 7.1e-37 127.2 4.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 RLN96934.1 - 8.2e-06 25.6 3.7 1.4e-05 24.9 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN96934.1 - 1.3e-05 24.9 2.1 2.3e-05 24.1 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN96934.1 - 0.0037 17.1 1.6 0.0075 16.1 1.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RLN96934.1 - 0.0038 17.5 1.8 0.0092 16.3 1.8 1.6 1 1 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 RLN96934.1 - 0.025 14.4 3.3 0.044 13.6 3.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 RLN96934.1 - 0.043 13.8 5.9 0.083 12.9 5.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 RLN96934.1 - 0.65 10.2 7.1 1.2 9.4 7.1 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Thiolase_N PF00108.23 RLN96935.1 - 8.2e-88 294.1 0.1 1.2e-87 293.5 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RLN96935.1 - 7.4e-45 151.6 2.1 1.2e-44 150.9 1.0 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 RLN96935.1 - 3.2e-05 23.6 1.3 3.2e-05 23.6 1.3 3.2 3 1 1 4 4 4 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 RLN96935.1 - 0.099 12.5 4.4 16 5.5 0.1 3.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF2431 PF10354.9 RLN96936.1 - 3.5e-37 128.3 0.0 5.4e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) FDX-ACB PF03147.14 RLN96936.1 - 2.8e-08 34.1 0.0 5.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain DUF3464 PF11947.8 RLN96937.1 - 0.0084 15.9 0.8 0.014 15.2 0.8 1.4 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 Kei1 PF08552.11 RLN96937.1 - 0.15 11.9 1.9 0.21 11.5 1.9 1.5 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 FUSC PF04632.12 RLN96937.1 - 8.1 4.8 8.7 17 3.8 8.7 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein family Endonuclease_NS PF01223.23 RLN96940.1 - 9.2e-53 179.4 0.0 1.3e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease MltA PF03562.17 RLN96940.1 - 0.037 13.8 0.0 0.056 13.2 0.0 1.3 1 1 0 1 1 1 0 MltA specific insert domain DUF4554 PF15091.6 RLN96941.1 - 9.3 5.0 10.4 11 4.8 10.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) LRR_4 PF12799.7 RLN96942.1 - 1.1e-16 60.7 32.0 4.7e-07 30.0 2.6 5.8 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN96942.1 - 9.8e-13 48.0 12.5 1.9e-11 43.8 1.5 3.2 2 1 1 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 RLN96942.1 - 6.2e-12 45.1 30.3 0.00057 19.6 5.9 5.5 5 0 0 5 5 5 3 Leucine rich repeat LRR_12 PF18837.1 RLN96942.1 - 3 7.6 6.7 11 5.7 0.1 3.2 3 0 0 3 3 3 0 Leucine-rich repeat RRM_1 PF00076.22 RLN96943.1 - 8.7e-17 60.7 0.1 3.9e-16 58.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN96943.1 - 0.0015 18.6 0.1 0.0062 16.6 0.0 2.0 2 1 0 2 2 2 1 RNA recognition motif Cut8 PF08559.10 RLN96943.1 - 0.064 12.8 0.1 0.088 12.4 0.1 1.2 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein RRM_3 PF08777.11 RLN96943.1 - 0.1 12.7 0.1 0.1 12.7 0.1 2.2 2 0 0 2 2 2 0 RNA binding motif RRM_1 PF00076.22 RLN96944.1 - 1.3e-15 56.9 0.0 1.8e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RLN96944.1 - 0.0012 18.9 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM PF05172.13 RLN96944.1 - 0.037 14.0 0.0 0.054 13.5 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SPRY PF00622.28 RLN96945.1 - 6.9e-39 132.7 1.0 5.3e-23 81.4 0.1 2.6 2 0 0 2 2 2 2 SPRY domain MIB_HERC2 PF06701.13 RLN96945.1 - 6.3e-18 64.8 5.9 1.9e-17 63.2 5.9 1.9 1 0 0 1 1 1 1 Mib_herc2 UBA PF00627.31 RLN96945.1 - 1.6e-14 53.5 3.4 2.7e-07 30.3 0.3 2.9 3 0 0 3 3 3 2 UBA/TS-N domain MutS_III PF05192.18 RLN96945.1 - 0.53 10.5 2.1 2.9 8.1 0.0 2.9 3 0 0 3 3 3 0 MutS domain III PHO4 PF01384.20 RLN96946.1 - 4.9e-96 321.7 18.8 6.4e-96 321.3 18.8 1.1 1 0 0 1 1 1 1 Phosphate transporter family YwiC PF14256.6 RLN96946.1 - 4 7.8 17.0 0.31 11.4 1.5 3.4 3 1 0 3 3 3 0 YwiC-like protein FXR_C1 PF16096.5 RLN96947.1 - 0.039 14.2 1.1 0.17 12.1 1.1 2.1 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 Dsl1_N PF11988.8 RLN96947.1 - 0.089 11.8 1.5 0.15 11.0 1.5 1.3 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 N terminal DUF4756 PF15948.5 RLN96947.1 - 0.11 12.3 1.9 0.4 10.5 1.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4756) T2SSppdC PF12528.8 RLN96947.1 - 3 8.7 5.4 0.97 10.2 2.2 1.9 2 0 0 2 2 2 0 Type II secretion prepilin peptidase dependent protein C Peptidase_M8 PF01457.16 RLN96948.1 - 2.9e-63 214.4 12.9 6.7e-47 160.4 8.9 2.7 3 0 0 3 3 3 2 Leishmanolysin SOG2 PF10428.9 RLN96948.1 - 0.44 9.7 10.6 0.61 9.2 10.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein MPS2 PF17060.5 RLN96949.1 - 0.2 10.9 5.0 0.3 10.3 5.0 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Uso1_p115_C PF04871.13 RLN96949.1 - 0.77 10.1 12.2 0.067 13.6 7.2 1.7 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region MPS2 PF17060.5 RLN96950.1 - 0.2 10.9 5.0 0.3 10.3 5.0 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Uso1_p115_C PF04871.13 RLN96950.1 - 0.77 10.1 12.2 0.067 13.6 7.2 1.7 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Lactonase PF10282.9 RLN96953.1 - 1.1e-87 294.5 0.0 1.3e-87 294.3 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Lipase_C PF18067.1 RLN96953.1 - 0.021 15.4 0.0 9.5 6.9 0.0 2.8 2 0 0 2 2 2 0 Lipase C-terminal domain ASH PF15780.5 RLN96954.1 - 2.7e-23 82.0 5.5 6.7e-06 26.2 0.1 8.4 8 1 0 8 8 8 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 RLN96954.1 - 6.2e-09 35.9 0.4 0.0024 18.0 0.0 5.7 7 0 0 7 7 7 2 Flagellar-associated PapD-like TMEM131_like PF12371.8 RLN96954.1 - 0.00061 20.0 0.0 0.19 12.0 0.0 3.9 4 0 0 4 4 4 1 Transmembrane protein 131-like LRR_6 PF13516.6 RLN96955.1 - 4.5e-16 57.5 5.7 0.001 18.9 0.7 5.6 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 RLN96955.1 - 1e-06 28.9 0.3 0.0033 17.8 0.1 3.6 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN96955.1 - 0.00024 20.8 3.5 0.043 13.6 0.4 3.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 RLN96955.1 - 0.017 15.6 0.0 23 6.1 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat DUF4691 PF15762.5 RLN96955.1 - 0.073 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4691) DUF724 PF05266.14 RLN96958.1 - 0.0038 17.1 12.6 0.0038 17.1 12.6 5.0 2 2 4 6 6 6 3 Protein of unknown function (DUF724) DUF465 PF04325.13 RLN96958.1 - 0.85 9.7 12.1 0.045 13.8 2.7 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Sec20 PF03908.13 RLN96958.1 - 2.7 8.0 16.4 0.29 11.1 0.8 4.0 2 1 1 3 3 3 0 Sec20 HOOK PF05622.12 RLN96958.1 - 9.2 4.3 66.3 0.17 10.0 5.4 3.7 2 1 1 3 3 3 0 HOOK protein DUF5575 PF17738.1 RLN96960.1 - 1.2e-06 27.8 0.3 1.2e-05 24.5 0.1 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5575) MULE PF10551.9 RLN96960.1 - 0.0008 19.8 0.0 0.0019 18.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 RLN96960.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Transposase Porin_3 PF01459.22 RLN96961.1 - 5.7e-09 35.8 0.0 9.9e-09 35.0 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic porin DNA_mis_repair PF01119.19 RLN96962.1 - 2.5e-21 75.5 0.7 5.6e-20 71.2 0.0 3.2 4 0 0 4 4 4 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 RLN96962.1 - 1.3e-20 73.7 0.2 4.8e-20 71.8 0.2 1.9 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 RLN96962.1 - 1.1e-07 31.8 0.1 2.5e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 RLN96962.1 - 1.8e-06 28.4 0.0 4.6e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CRAL_TRIO PF00650.20 RLN96963.1 - 0.028 14.1 0.0 0.057 13.1 0.0 1.5 2 0 0 2 2 2 0 CRAL/TRIO domain ABC2_membrane PF01061.24 RLN96964.1 - 2.3e-28 99.1 21.3 4e-28 98.3 21.3 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN96964.1 - 1.5e-20 74.1 0.0 2.3e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN96964.1 - 2.3e-10 40.8 0.0 0.0003 20.7 0.0 2.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 RLN96964.1 - 2.5e-05 24.0 0.0 0.00023 20.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN96964.1 - 8.2e-05 23.0 0.1 0.0011 19.4 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 RLN96964.1 - 0.00062 19.5 0.2 0.0015 18.2 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN96964.1 - 0.0021 18.6 0.1 0.0035 17.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 RLN96964.1 - 0.006 16.5 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 RLN96964.1 - 0.0066 16.2 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RLN96964.1 - 0.01 16.1 0.0 0.026 14.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RLN96964.1 - 0.013 15.5 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 RLN96964.1 - 0.061 12.8 0.0 3.2 7.1 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 RLN96964.1 - 0.064 13.5 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RLN96964.1 - 0.096 13.2 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RLN96964.1 - 0.1 12.8 0.1 0.26 11.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 RLN96964.1 - 0.18 11.7 1.2 0.26 11.2 0.1 1.8 2 0 0 2 2 2 0 NACHT domain ABC2_membrane_3 PF12698.7 RLN96964.1 - 2.1 7.4 26.1 1.5 7.9 22.4 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein LysR_substrate PF03466.20 RLN96965.1 - 0.0082 15.5 0.0 0.026 13.9 0.0 1.8 1 0 0 1 1 1 1 LysR substrate binding domain SAS-6_N PF16531.5 RLN96966.1 - 1.1e-31 109.3 0.1 2.2e-31 108.3 0.1 1.5 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal Fib_alpha PF08702.10 RLN96966.1 - 0.034 14.3 1.3 0.069 13.3 1.3 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family MAT1 PF06391.13 RLN96966.1 - 0.11 12.3 7.8 0.38 10.6 2.9 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF1043 PF06295.12 RLN96966.1 - 2.3 8.2 8.2 0.39 10.7 3.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF3347 PF11827.8 RLN96966.1 - 7.7 6.7 8.9 21 5.2 8.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) Ysc84 PF04366.12 RLN96967.1 - 4.1e-35 120.3 0.6 7.6e-35 119.5 0.6 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator FYVE PF01363.21 RLN96967.1 - 1.2e-11 44.6 10.7 1.2e-11 44.6 10.7 2.9 3 0 0 3 3 3 1 FYVE zinc finger SPX PF03105.19 RLN96967.1 - 0.13 12.1 9.8 0.24 11.3 3.8 2.1 2 0 0 2 2 2 0 SPX domain HypA PF01155.19 RLN96967.1 - 0.14 12.2 10.7 0.1 12.7 1.7 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 RLN96967.1 - 6 6.9 14.5 0.037 14.0 2.0 2.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DEAD PF00270.29 RLN96968.1 - 5.6e-49 166.3 0.0 1.5e-47 161.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN96968.1 - 6.9e-33 113.3 0.0 1.9e-32 111.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN96968.1 - 0.0036 17.3 0.0 0.015 15.3 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Tektin PF03148.14 RLN96969.1 - 0.0045 15.8 6.3 0.0045 15.8 6.3 2.1 1 1 1 2 2 2 1 Tektin family DUF3450 PF11932.8 RLN96969.1 - 0.012 15.0 8.2 0.012 15.0 8.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BRE1 PF08647.11 RLN96969.1 - 0.018 15.1 10.1 0.018 15.1 10.1 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Gal-3-0_sulfotr PF06990.11 RLN96969.1 - 0.02 13.8 0.8 0.027 13.3 0.7 1.3 1 1 0 1 1 1 0 Galactose-3-O-sulfotransferase PCRF PF03462.18 RLN96969.1 - 0.039 13.8 12.2 0.05 13.5 12.2 1.1 1 0 0 1 1 1 0 PCRF domain DUF4041 PF13250.6 RLN96969.1 - 0.044 13.6 0.5 0.11 12.4 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) Lebercilin PF15619.6 RLN96969.1 - 0.059 13.0 27.5 0.071 12.8 27.5 1.0 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 RLN96969.1 - 0.062 12.2 22.3 0.082 11.8 22.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 RLN96969.1 - 0.16 12.1 26.7 0.03 14.5 15.7 2.2 1 1 0 2 2 2 0 Tropomyosin like DUF4201 PF13870.6 RLN96969.1 - 0.17 11.6 22.2 0.2 11.4 22.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) YjcZ PF13990.6 RLN96969.1 - 0.19 11.1 8.2 0.05 13.0 5.2 1.5 1 1 1 2 2 2 0 YjcZ-like protein DUF4407 PF14362.6 RLN96969.1 - 0.29 10.5 14.6 0.39 10.0 14.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF16 PF01519.16 RLN96969.1 - 0.38 11.3 21.3 0.1 13.1 10.0 2.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF4795 PF16043.5 RLN96969.1 - 0.63 9.6 20.0 1.7 8.2 15.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF812 PF05667.11 RLN96969.1 - 1.1 8.1 21.0 1.3 7.8 21.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Baculo_PEP_C PF04513.12 RLN96969.1 - 1.3 9.1 9.7 8.8 6.4 9.7 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus GBP_C PF02841.14 RLN96969.1 - 1.5 8.1 21.3 2 7.7 21.3 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain SlyX PF04102.12 RLN96969.1 - 2 9.1 19.4 0.21 12.2 7.4 3.2 1 1 2 3 3 3 0 SlyX GAS PF13851.6 RLN96969.1 - 2.2 7.6 26.3 10 5.4 23.8 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 RLN96969.1 - 2.7 8.2 18.4 0.35 11.0 4.9 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 RLN96969.1 - 2.8 8.0 25.9 0.39 10.8 10.9 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TSC22 PF01166.18 RLN96969.1 - 3.2 8.1 11.5 0.11 12.8 3.5 2.7 1 1 0 2 2 2 0 TSC-22/dip/bun family Fez1 PF06818.15 RLN96969.1 - 3.5 8.0 24.0 9.3 6.6 24.0 1.6 1 1 0 1 1 1 0 Fez1 ZapB PF06005.12 RLN96969.1 - 3.6 8.1 24.6 1.8e+04 -3.8 24.6 3.4 1 1 0 1 1 0 0 Cell division protein ZapB Tup_N PF08581.10 RLN96969.1 - 4.8 7.5 19.1 4.7 7.6 3.1 2.6 2 1 0 2 2 2 0 Tup N-terminal Jnk-SapK_ap_N PF09744.9 RLN96969.1 - 5 7.3 24.2 0.092 13.0 9.8 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF4200 PF13863.6 RLN96969.1 - 6 7.3 24.8 6.7 7.1 12.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) MctB PF11382.8 RLN96969.1 - 8.8 5.9 10.1 20 4.8 4.9 2.1 1 1 1 2 2 2 0 Copper transport outer membrane protein, MctB adh_short_C2 PF13561.6 RLN96970.1 - 1e-56 192.2 5.3 1.1e-56 192.0 5.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RLN96970.1 - 5.3e-49 166.3 2.8 6.5e-49 166.0 2.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RLN96970.1 - 1.4e-11 44.6 2.4 2.5e-11 43.8 2.4 1.4 1 0 0 1 1 1 1 KR domain Seadorna_Vp10 PF07322.11 RLN96970.1 - 0.19 11.1 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus Vp10 4HBT PF03061.22 RLN96971.1 - 3e-13 49.9 0.1 3.4e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily HTH_6 PF01418.17 RLN96972.1 - 0.16 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family ABC2_membrane PF01061.24 RLN96973.1 - 3.5e-29 101.7 26.1 6.1e-29 101.0 26.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RLN96973.1 - 5.7e-21 75.5 0.0 9.1e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN96973.1 - 3.3e-10 40.3 0.0 0.0001 22.3 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN96973.1 - 1.2e-05 25.8 0.0 2.8e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 RLN96973.1 - 0.001 19.6 0.0 0.0017 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 RLN96973.1 - 0.001 18.8 0.1 0.0027 17.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN96973.1 - 0.0019 17.8 0.0 0.0064 16.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RLN96973.1 - 0.0024 18.1 0.0 0.0068 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 RLN96973.1 - 0.0083 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 RLN96973.1 - 0.011 15.2 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 RLN96973.1 - 0.024 14.3 0.1 0.044 13.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RLN96973.1 - 0.026 14.7 0.5 0.17 12.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 RLN96973.1 - 0.057 13.3 0.0 0.67 9.8 0.0 2.1 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.12 RLN96973.1 - 0.076 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 RLN96973.1 - 0.081 13.2 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 RLN96973.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 RLN96973.1 - 0.19 10.7 0.0 0.35 9.8 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 RLN96973.1 - 0.2 12.2 0.0 0.39 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 RLN96973.1 - 3 6.8 27.4 4.6 6.3 27.4 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein K-box PF01486.17 RLN96974.1 - 1.2e-08 35.0 3.0 2.5e-08 34.0 3.0 1.5 1 0 0 1 1 1 1 K-box region TMF_DNA_bd PF12329.8 RLN96974.1 - 0.31 11.1 5.1 0.16 12.0 0.4 2.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Prominin PF05478.11 RLN96974.1 - 0.33 8.9 0.1 0.46 8.4 0.1 1.1 1 0 0 1 1 1 0 Prominin Dynamitin PF04912.14 RLN96974.1 - 0.36 10.1 7.7 1.9 7.7 7.7 1.8 1 1 0 1 1 1 0 Dynamitin FapA PF03961.13 RLN96974.1 - 0.47 9.0 1.8 0.62 8.6 1.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A HIP1_clath_bdg PF16515.5 RLN96974.1 - 0.47 11.1 6.1 1.6 9.4 2.4 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc24 PF08286.11 RLN96974.1 - 0.52 10.6 4.0 1.9 8.8 0.5 2.5 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Tropomyosin_1 PF12718.7 RLN96974.1 - 0.54 10.4 5.1 0.99 9.6 4.8 1.6 1 1 0 1 1 1 0 Tropomyosin like APG6_N PF17675.1 RLN96974.1 - 1 9.9 10.3 1.3 9.6 2.4 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region BST2 PF16716.5 RLN96974.1 - 1 10.0 6.2 0.51 11.0 2.5 2.2 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Seryl_tRNA_N PF02403.22 RLN96974.1 - 3.2 8.0 5.8 15 5.8 0.4 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain LapA_dom PF06305.11 RLN96974.1 - 5.2 7.0 12.4 0.6 10.0 1.8 3.5 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain GAS PF13851.6 RLN96974.1 - 7.6 5.8 7.5 24 4.2 7.5 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Ribonuc_red_lgC PF02867.15 RLN96975.1 - 2e-185 617.3 0.0 2.4e-185 617.0 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 RLN96975.1 - 3.9e-24 84.5 0.1 2.5e-22 78.7 0.0 2.5 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 RLN96975.1 - 4e-18 65.8 0.0 9.5e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain FKBP_C PF00254.28 RLN96976.1 - 5.2e-50 167.7 0.0 3e-32 110.8 0.0 2.3 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TP_methylase PF00590.20 RLN96977.1 - 1.1e-42 146.3 1.0 1.4e-42 146.1 1.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Myb_DNA-binding PF00249.31 RLN96978.1 - 1.4e-38 130.8 9.7 2.4e-12 46.9 0.0 6.2 5 1 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN96978.1 - 4.1e-29 100.6 5.1 6.4e-11 42.3 0.6 5.0 3 1 1 4 4 4 4 Myb-like DNA-binding domain SLIDE PF09111.10 RLN96978.1 - 0.002 18.1 0.0 17 5.5 0.0 4.1 3 0 0 3 3 3 2 SLIDE Rap1_C PF11626.8 RLN96978.1 - 1.4 9.1 4.4 42 4.3 1.8 3.4 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain 4HBT PF03061.22 RLN96979.1 - 6.8e-08 32.8 0.6 1.4e-07 31.8 0.6 1.5 1 0 0 1 1 1 1 Thioesterase superfamily YiiD_C PF09500.10 RLN96979.1 - 0.039 13.8 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) 4HBT PF03061.22 RLN96980.1 - 0.0031 17.8 0.1 0.009 16.4 0.0 1.8 2 0 0 2 2 2 1 Thioesterase superfamily Lipase_3 PF01764.25 RLN96981.1 - 3.5e-06 26.9 0.0 1e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 RLN96981.1 - 0.00011 22.9 0.0 0.00019 22.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 RLN96981.1 - 0.0062 16.3 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 RLN96981.1 - 0.03 13.6 0.2 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN96981.1 - 0.065 12.9 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.12 RLN96981.1 - 0.07 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2974 PF11187.8 RLN96981.1 - 0.13 11.8 0.2 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PDCD2_C PF04194.13 RLN96982.1 - 6.6e-35 120.7 3.3 3e-34 118.6 0.0 2.3 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain AFG1_ATPase PF03969.16 RLN96983.1 - 2.3e-95 319.6 3.8 3.3e-91 305.9 1.4 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 RLN96983.1 - 8.3e-05 23.0 3.0 0.00021 21.7 0.2 2.9 1 1 2 3 3 3 1 AAA ATPase domain Bac_DnaA PF00308.18 RLN96983.1 - 0.00028 20.8 0.0 0.088 12.6 0.0 2.3 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_22 PF13401.6 RLN96983.1 - 0.0024 18.1 0.4 0.014 15.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 RLN96983.1 - 0.074 13.5 0.0 1.6 9.1 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pex26 PF07163.12 RLN96984.1 - 0.0021 17.4 0.9 0.0032 16.9 0.9 1.2 1 0 0 1 1 1 1 Pex26 protein BAR PF03114.18 RLN96984.1 - 0.0063 16.2 1.8 0.0095 15.6 1.8 1.2 1 0 0 1 1 1 1 BAR domain Peptidase_M13_N PF05649.13 RLN96984.1 - 0.067 12.9 0.4 0.1 12.3 0.4 1.2 1 0 0 1 1 1 0 Peptidase family M13 Cor1 PF04803.12 RLN96984.1 - 0.11 12.7 2.8 0.15 12.3 1.4 1.9 1 1 1 2 2 2 0 Cor1/Xlr/Xmr conserved region FHA PF00498.26 RLN96987.1 - 8.1e-12 45.3 0.0 1.3e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RLN96987.1 - 2.5e-06 27.7 0.0 7.6e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain CM_2 PF01817.21 RLN96987.1 - 0.016 15.6 0.6 0.034 14.5 0.6 1.6 1 0 0 1 1 1 0 Chorismate mutase type II PHD20L1_u1 PF16660.5 RLN96987.1 - 1.3 9.8 5.1 1.6 9.5 0.2 3.2 3 0 0 3 3 3 0 PHD finger protein 20-like protein 1 HTH_23 PF13384.6 RLN96988.1 - 0.00031 20.5 1.0 0.0009 19.0 1.0 1.9 1 1 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_1 PF01527.20 RLN96988.1 - 0.0025 18.1 0.2 0.0049 17.2 0.2 1.4 1 0 0 1 1 1 1 Transposase CENP-B_N PF04218.13 RLN96988.1 - 0.0088 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 RLN96988.1 - 0.02 14.6 0.1 0.042 13.6 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 RLN96988.1 - 0.041 14.0 2.9 0.19 11.9 2.9 2.1 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 RLN96988.1 - 0.073 13.2 0.1 0.3 11.2 0.0 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain of resolvase HTH_10 PF04967.12 RLN96988.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HECW_N PF16562.5 RLN96988.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 HTH_29 PF13551.6 RLN96988.1 - 0.38 10.8 3.9 2.7 8.1 1.8 2.8 2 1 0 2 2 2 0 Winged helix-turn helix ArfGap PF01412.18 RLN96989.1 - 3.1e-16 59.5 3.1 5.3e-16 58.7 3.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-ribbon_3 PF13248.6 RLN96989.1 - 0.68 9.4 4.1 7.2 6.2 1.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain SnoaL_2 PF12680.7 RLN96990.1 - 0.00013 22.5 0.0 0.00023 21.7 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain LEH PF07858.12 RLN96990.1 - 0.0064 16.6 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain SnoaL PF07366.12 RLN96990.1 - 0.011 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase DUF2358 PF10184.9 RLN96990.1 - 0.063 13.6 0.0 0.089 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) Ank_4 PF13637.6 RLN96992.1 - 2.2e-38 130.1 9.5 5.4e-10 39.6 0.1 7.7 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN96992.1 - 3.6e-36 122.7 17.5 3e-13 49.7 0.3 5.9 3 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN96992.1 - 4.8e-34 116.8 5.7 1.4e-10 41.7 0.1 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN96992.1 - 7.4e-31 102.7 8.0 0.00012 22.2 0.1 8.6 8 0 0 8 8 8 8 Ankyrin repeat Ank PF00023.30 RLN96992.1 - 9.7e-30 101.7 16.8 0.00011 22.5 1.0 7.7 8 0 0 8 8 8 7 Ankyrin repeat Biotin_carb_C PF02785.19 RLN96992.1 - 0.0026 17.9 0.0 0.0059 16.7 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain NifQ PF04891.12 RLN96992.1 - 0.024 15.0 0.7 0.042 14.2 0.7 1.4 1 0 0 1 1 1 0 NifQ MatE PF01554.18 RLN96996.1 - 1.2e-53 181.1 28.6 4.2e-28 98.0 3.4 2.7 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 RLN96996.1 - 0.11 12.6 40.0 0.049 13.7 16.0 4.6 2 2 2 4 4 4 0 Polysaccharide biosynthesis C-terminal domain Pkinase_Tyr PF07714.17 RLN96997.1 - 1.3e-32 113.2 0.0 2.3e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN96997.1 - 1.7e-30 106.3 0.0 2.4e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 RLN96997.1 - 0.0011 17.9 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN96997.1 - 0.098 12.6 4.4 0.52 10.2 4.4 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.32 RLN96998.1 - 2.2e-17 63.1 2.0 3.2e-05 24.6 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN96998.1 - 3e-09 37.0 0.0 0.0014 18.9 0.0 3.5 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain MatE PF01554.18 RLN96999.1 - 1.6e-53 180.7 31.3 7.3e-29 100.5 1.9 3.0 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 RLN96999.1 - 0.0035 17.4 13.4 0.0035 17.4 13.4 4.4 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain GAS PF13851.6 RLN97000.1 - 0.0035 16.7 11.7 0.0091 15.4 0.6 2.0 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Cytochrom_B562 PF07361.11 RLN97000.1 - 0.01 16.5 1.3 0.012 16.3 0.2 1.6 2 0 0 2 2 1 0 Cytochrome b562 Atg14 PF10186.9 RLN97000.1 - 0.015 14.4 1.0 0.038 13.1 1.0 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 RLN97000.1 - 0.02 13.8 8.0 0.032 13.1 8.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein HalX PF08663.10 RLN97000.1 - 0.025 14.9 6.4 0.025 14.9 6.4 2.9 2 1 0 2 2 2 0 HalX domain ATG16 PF08614.11 RLN97000.1 - 0.025 14.8 5.0 0.025 14.8 5.0 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 RLN97000.1 - 0.025 15.0 7.8 0.033 14.6 7.8 1.1 1 0 0 1 1 1 0 Fez1 Prominin PF05478.11 RLN97000.1 - 0.048 11.6 1.6 0.058 11.4 1.6 1.0 1 0 0 1 1 1 0 Prominin LMBR1 PF04791.16 RLN97000.1 - 0.055 12.4 1.3 0.064 12.2 1.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein FlaC_arch PF05377.11 RLN97000.1 - 0.064 13.7 7.0 0.082 13.3 0.6 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Helo_like_N PF17111.5 RLN97000.1 - 0.077 12.3 10.6 0.18 11.2 0.2 3.0 1 1 2 3 3 3 0 Fungal N-terminal domain of STAND proteins HisKA PF00512.25 RLN97000.1 - 0.079 13.0 0.8 0.079 13.0 0.8 2.6 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain DUF948 PF06103.11 RLN97000.1 - 0.12 12.7 2.4 0.63 10.3 0.1 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Hydantoinase_B PF02538.14 RLN97000.1 - 0.14 10.5 2.7 0.11 10.9 1.7 1.4 1 1 0 1 1 1 0 Hydantoinase B/oxoprolinase IZUMO PF15005.6 RLN97000.1 - 0.15 12.6 3.1 0.19 12.2 3.1 1.2 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated CENP-Q PF13094.6 RLN97000.1 - 0.22 11.7 11.4 0.36 11.0 2.1 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CENP-H PF05837.12 RLN97000.1 - 0.26 11.7 6.9 0.36 11.3 2.9 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) NPV_P10 PF05531.12 RLN97000.1 - 0.36 11.3 5.0 3.7 8.1 0.5 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Sec34 PF04136.15 RLN97000.1 - 0.38 10.6 4.7 7.2 6.5 1.6 2.2 1 1 2 3 3 3 0 Sec34-like family BLOC1_2 PF10046.9 RLN97000.1 - 0.43 10.9 6.7 0.61 10.4 0.5 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.19 RLN97000.1 - 0.45 8.4 2.5 0.5 8.2 2.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2968 PF11180.8 RLN97000.1 - 0.5 10.0 8.8 0.34 10.5 5.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DivIC PF04977.15 RLN97000.1 - 0.65 9.8 12.2 0.52 10.1 0.7 2.5 2 1 0 2 2 2 0 Septum formation initiator Seryl_tRNA_N PF02403.22 RLN97000.1 - 0.78 10.0 10.2 0.62 10.3 1.6 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Shugoshin_N PF07558.11 RLN97000.1 - 0.83 9.6 5.4 2.5 8.1 0.5 2.6 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF1664 PF07889.12 RLN97000.1 - 1.1 9.3 3.7 1.3 9.1 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) MIP-T3_C PF17749.1 RLN97000.1 - 1.2 9.1 8.1 0.43 10.5 0.4 2.2 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region APG6_N PF17675.1 RLN97000.1 - 1.7 9.2 19.5 0.3 11.6 6.6 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Phage_GPO PF05929.11 RLN97000.1 - 2.1 7.9 5.9 4.7 6.8 5.9 1.5 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase P4Ha_N PF08336.11 RLN97000.1 - 2.3 8.2 8.9 12 5.9 0.5 2.4 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF2203 PF09969.9 RLN97000.1 - 2.6 8.8 7.9 1.1 9.9 0.3 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) CCDC-167 PF15188.6 RLN97000.1 - 5.1 7.5 11.3 1.7 9.0 6.0 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 zf-C4H2 PF10146.9 RLN97000.1 - 7.9 6.7 7.1 22 5.3 7.1 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein DUF4404 PF14357.6 RLN97000.1 - 8.8 7.0 11.9 1.1 10.0 5.0 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) WD40 PF00400.32 RLN97001.1 - 2.1e-10 41.0 10.2 0.003 18.4 0.2 7.4 8 1 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN97001.1 - 1.4e-05 25.3 0.1 0.42 10.9 0.0 4.5 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain CENP-L PF13092.6 RLN97002.1 - 1.2e-05 25.5 0.0 2.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 HEAT PF02985.22 RLN97003.1 - 4.3e-06 26.5 13.5 0.086 13.1 0.0 6.0 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 RLN97003.1 - 0.015 15.6 11.2 7.3 7.1 0.0 6.8 5 1 0 6 6 6 0 HEAT repeats CLASP_N PF12348.8 RLN97003.1 - 0.44 10.1 2.1 22 4.5 0.0 3.9 5 0 0 5 5 5 0 CLASP N terminal Arm PF00514.23 RLN97003.1 - 2.9 8.0 5.0 17 5.6 0.1 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Glyco_hydro_85 PF03644.13 RLN97005.1 - 1.7e-48 165.6 0.2 5.8e-29 101.5 0.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 85 FixQ PF05545.11 RLN97005.1 - 0.15 12.0 0.8 0.32 11.0 0.8 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ ABC_cobalt PF09819.9 RLN97005.1 - 0.34 11.1 2.4 0.22 11.7 0.3 1.7 2 0 0 2 2 2 0 ABC-type cobalt transport system, permease component P16-Arc PF04699.14 RLN97008.1 - 2.1e-27 96.5 0.2 2.9e-27 96.0 0.2 1.3 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) UBA PF00627.31 RLN97008.1 - 0.2 11.6 4.2 7.9 6.5 0.2 2.7 2 0 0 2 2 2 0 UBA/TS-N domain Abhydrolase_3 PF07859.13 RLN97009.1 - 3.7e-13 49.8 0.2 6.7e-13 49.0 0.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 RLN97009.1 - 8.8e-08 31.5 0.0 0.0039 16.1 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_6 PF12697.7 RLN97009.1 - 3.2e-05 24.7 0.3 4e-05 24.3 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 RLN97009.1 - 0.004 16.7 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Peptidase_S9 PF00326.21 RLN97009.1 - 0.034 13.6 0.0 0.28 10.6 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family CoA_transf_3 PF02515.17 RLN97010.1 - 2e-110 369.4 0.0 2.5e-110 369.1 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Thioredoxin_8 PF13905.6 RLN97010.1 - 5.2e-19 68.4 0.0 1e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 RLN97010.1 - 6.9e-05 22.8 0.0 0.083 12.9 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 RLN97010.1 - 0.00027 21.4 0.0 0.00068 20.1 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 RLN97010.1 - 0.0026 17.5 0.0 0.28 10.9 0.0 2.5 1 1 1 2 2 2 1 Thioredoxin DeoC PF01791.9 RLN97010.1 - 0.08 12.5 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 DeoC/LacD family aldolase DcpS PF05652.12 RLN97011.1 - 4.2e-13 50.0 0.0 7.8e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 RLN97011.1 - 5.3e-11 43.0 3.1 9.4e-11 42.2 3.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding PLDc PF00614.22 RLN97012.1 - 5e-08 32.8 0.1 1.4e-07 31.4 0.1 1.9 1 0 0 1 1 1 1 Phospholipase D Active site motif PLDc_2 PF13091.6 RLN97012.1 - 0.0074 16.2 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 PLD-like domain PX PF00787.24 RLN97012.1 - 0.058 13.4 0.2 0.12 12.4 0.2 1.5 1 0 0 1 1 1 0 PX domain RNA_lig_T4_1 PF09511.10 RLN97013.1 - 0.023 14.5 0.0 0.074 12.9 0.0 1.8 2 0 0 2 2 2 0 RNA ligase Coilin_N PF15862.5 RLN97013.1 - 0.13 12.1 1.8 0.31 10.8 1.8 1.7 1 0 0 1 1 1 0 Coilin N-terminus WD40 PF00400.32 RLN97014.1 - 1.1e-38 130.5 14.0 9.1e-08 32.7 0.2 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN97014.1 - 1.3e-08 35.0 2.2 0.25 11.7 0.0 6.9 5 2 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN97014.1 - 0.013 14.1 0.1 0.78 8.3 0.1 3.1 3 1 0 3 3 3 0 Nucleoporin Nup120/160 FYVE_2 PF02318.16 RLN97014.1 - 0.065 13.5 11.7 0.25 11.6 11.6 2.0 1 1 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 RLN97014.1 - 0.59 10.3 13.6 1.6 8.9 13.6 1.7 1 0 0 1 1 1 0 FYVE zinc finger SpoIIIAC PF06686.11 RLN97016.1 - 0.099 12.8 1.7 11 6.2 0.0 3.4 3 0 0 3 3 3 0 Stage III sporulation protein AC/AD protein family DEC-1_N PF04625.13 RLN97017.1 - 1.1 8.2 7.8 1.5 7.8 7.8 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Aminotran_1_2 PF00155.21 RLN97018.1 - 1.3e-58 198.9 0.0 1.7e-58 198.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II PDT PF00800.18 RLN97018.1 - 4.3e-11 42.9 0.1 1.7e-10 41.0 0.1 1.9 1 1 1 2 2 2 1 Prephenate dehydratase Cys_Met_Meta_PP PF01053.20 RLN97018.1 - 0.00085 18.0 0.0 0.0051 15.4 0.0 1.9 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme ACT PF01842.25 RLN97018.1 - 0.012 15.4 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 ACT domain 3HCDH_RFF PF18321.1 RLN97018.1 - 0.053 14.0 0.5 0.73 10.3 0.0 2.7 3 0 0 3 3 3 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain bZIP_2 PF07716.15 RLN97019.1 - 0.0027 17.8 8.2 0.0027 17.8 8.2 2.4 2 0 0 2 2 2 1 Basic region leucine zipper HBM PF16591.5 RLN97019.1 - 0.023 14.1 7.0 0.036 13.5 7.0 1.2 1 0 0 1 1 1 0 Helical bimodular sensor domain FlgN PF05130.12 RLN97019.1 - 0.15 12.5 7.7 0.34 11.4 7.7 1.5 1 0 0 1 1 1 0 FlgN protein BssS PF13991.6 RLN97019.1 - 0.18 11.9 1.1 31 4.7 0.0 3.1 2 1 2 4 4 4 0 BssS protein family ABC_tran_CTD PF16326.5 RLN97019.1 - 0.39 11.0 5.7 0.087 13.1 1.4 2.1 1 1 0 1 1 1 0 ABC transporter C-terminal domain bZIP_1 PF00170.21 RLN97019.1 - 0.68 10.1 8.7 0.54 10.4 6.8 1.8 1 1 0 1 1 1 0 bZIP transcription factor DUF523 PF04463.12 RLN97020.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF523) bZIP_2 PF07716.15 RLN97020.1 - 0.18 11.9 17.0 0.093 12.8 14.0 2.2 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 RLN97020.1 - 3.8 7.7 15.1 9.1 6.5 13.4 2.4 2 1 0 2 2 2 0 bZIP transcription factor Carb_anhydrase PF00194.21 RLN97022.1 - 3.8e-38 131.5 0.0 5.8e-38 130.9 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase PRA-CH PF01502.18 RLN97023.1 - 5e-26 90.3 0.1 1.1e-25 89.2 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 RLN97023.1 - 5.7e-10 39.5 0.1 1.3e-09 38.4 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase ORF6N PF10543.9 RLN97023.1 - 0.14 12.4 0.0 0.42 10.9 0.0 1.9 2 0 0 2 2 2 0 ORF6N domain UCR_UQCRX_QCR9 PF05365.12 RLN97024.1 - 2.5e-12 46.5 1.5 3.5e-12 46.1 1.5 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Shisa PF13908.6 RLN97025.1 - 0.00049 20.4 0.6 0.00082 19.7 0.6 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Baculo_11_kDa PF06143.11 RLN97025.1 - 0.0037 16.8 4.0 0.0079 15.8 4.0 1.5 1 0 0 1 1 1 1 Baculovirus 11 kDa family RIFIN PF02009.16 RLN97025.1 - 0.0059 16.5 3.7 0.019 14.9 3.7 1.9 1 0 0 1 1 1 1 Rifin DUF1700 PF08006.11 RLN97025.1 - 0.011 15.3 3.6 0.018 14.6 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) T2SSF PF00482.23 RLN97025.1 - 0.016 15.2 0.7 0.044 13.7 0.1 2.1 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F LAP1C PF05609.12 RLN97025.1 - 0.023 13.8 1.5 0.076 12.1 0.0 1.9 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) LRRC37AB_C PF14914.6 RLN97025.1 - 0.032 14.1 1.3 0.079 12.9 1.3 1.6 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Orf78 PF06024.12 RLN97025.1 - 0.034 14.4 3.3 0.089 13.1 2.8 1.8 1 1 0 1 1 1 0 Orf78 (ac78) DUF2207 PF09972.9 RLN97025.1 - 0.043 12.6 0.3 0.078 11.7 0.1 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF898 PF05987.13 RLN97025.1 - 0.15 11.1 2.9 0.22 10.5 2.9 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF3169 PF11368.8 RLN97025.1 - 0.27 10.7 11.0 0.63 9.5 9.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) TMEM154 PF15102.6 RLN97025.1 - 0.52 10.2 10.4 0.24 11.3 7.6 1.8 1 1 0 2 2 2 0 TMEM154 protein family PBP1_TM PF14812.6 RLN97025.1 - 0.62 10.5 0.0 0.62 10.5 0.0 2.4 2 1 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3357 PF11837.8 RLN97025.1 - 3.4 8.2 7.0 19 5.7 0.2 2.9 2 1 1 3 3 2 0 Domain of unknown function (DUF3357) EphA2_TM PF14575.6 RLN97025.1 - 5.3 8.0 7.8 3.5e+02 2.2 8.8 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Acetyltransf_1 PF00583.25 RLN97028.1 - 6.3e-40 136.1 0.5 5.1e-14 52.5 0.0 3.2 3 0 0 3 3 3 3 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RLN97028.1 - 1.7e-29 102.1 0.3 5.6e-11 42.7 0.0 3.3 3 0 0 3 3 3 3 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RLN97028.1 - 4.8e-28 97.6 0.4 6e-10 39.2 0.1 3.2 3 0 0 3 3 3 3 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN97028.1 - 1.2e-12 47.6 3.2 8.7e-05 22.4 0.1 3.4 3 0 0 3 3 3 3 FR47-like protein Acetyltransf_3 PF13302.7 RLN97028.1 - 6.9e-12 46.2 1.5 0.004 17.8 0.0 3.2 3 0 0 3 3 3 3 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 RLN97028.1 - 9.2e-07 28.9 0.3 0.054 13.6 0.0 3.6 3 0 0 3 3 3 2 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 RLN97028.1 - 5.8e-06 26.5 1.6 3.9 7.6 0.0 4.8 5 0 0 5 5 5 2 Acetyltransferase (GNAT) domain PanZ PF12568.8 RLN97028.1 - 7.5e-05 22.5 0.3 2.7 7.8 0.0 3.5 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_4 PF13420.7 RLN97028.1 - 8.4e-05 22.7 0.0 0.47 10.6 0.0 3.5 3 1 0 3 3 3 2 Acetyltransferase (GNAT) domain Transketolase_C PF02780.20 RLN97028.1 - 0.0013 18.6 0.0 1.9 8.4 0.0 3.1 3 0 0 3 3 3 2 Transketolase, C-terminal domain Acetyltransf_13 PF13880.6 RLN97028.1 - 0.013 15.4 1.9 11 6.1 0.0 3.4 3 0 0 3 3 3 0 ESCO1/2 acetyl-transferase Acetyltransf_9 PF13527.7 RLN97028.1 - 0.054 13.6 4.7 0.73 9.9 0.1 4.2 4 2 1 5 5 5 0 Acetyltransferase (GNAT) domain FluMu_N PF17891.1 RLN97028.1 - 0.056 13.2 1.0 5.5 6.8 0.0 3.1 3 0 0 3 3 2 0 Mu-like prophage FluMu N-terminal domain IBV_3B PF03622.13 RLN97028.1 - 0.086 13.0 0.4 36 4.6 0.0 3.2 3 0 0 3 3 3 0 IBV 3B protein ParcG PF10274.9 RLN97029.1 - 3.7e-66 222.7 0.0 4.3e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein GT87 PF09594.10 RLN97030.1 - 0.04 13.6 0.4 0.058 13.1 0.4 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 87 Pkinase PF00069.25 RLN97031.1 - 2.8e-42 144.9 0.0 3.8e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97031.1 - 5.5e-33 114.3 0.0 7.3e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN97031.1 - 1.4e-05 24.1 0.0 0.00011 21.2 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 RLN97031.1 - 0.00047 19.6 0.1 0.00069 19.0 0.1 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RLN97031.1 - 0.0013 17.8 0.0 0.0023 17.0 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RLN97031.1 - 0.0039 17.1 0.1 0.0061 16.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RLN97031.1 - 0.018 14.4 0.1 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 RLN97031.1 - 0.019 14.6 0.0 0.95 9.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 RLN97031.1 - 0.026 13.6 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pro-kuma_activ PF09286.11 RLN97032.1 - 1.5e-22 80.5 0.0 3.3e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 RLN97032.1 - 2.8e-06 26.8 0.2 6.7e-06 25.6 0.2 1.6 2 0 0 2 2 2 1 Subtilase family BT1 PF03092.16 RLN97033.1 - 1.3e-09 36.9 0.6 1.3e-09 36.9 0.6 2.1 2 1 0 3 3 3 1 BT1 family Vma12 PF11712.8 RLN97033.1 - 2.5 8.1 5.6 0.38 10.8 1.0 2.0 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Acetyltransf_1 PF00583.25 RLN97034.1 - 1e-14 54.7 0.0 1.3e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RLN97034.1 - 1.1e-10 41.8 0.0 1.5e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RLN97034.1 - 6.7e-10 39.0 0.0 8e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 RLN97034.1 - 1.7e-06 28.8 0.1 2e-06 28.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN97034.1 - 2.6e-05 24.1 0.0 4.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 RLN97034.1 - 4.1e-05 23.7 0.0 6.3e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain T6SS-SciN PF12790.7 RLN97034.1 - 0.039 13.7 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 Acetyltransf_9 PF13527.7 RLN97034.1 - 0.044 13.9 0.2 3.4 7.8 0.1 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 RLN97034.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 RLN97034.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 RLN97035.1 - 2.3e-63 211.7 1.3 3.2e-14 53.2 0.0 4.3 4 0 0 4 4 4 4 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RLN97035.1 - 2.9e-45 152.6 0.3 1e-09 38.6 0.0 4.3 4 0 0 4 4 4 4 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RLN97035.1 - 4.2e-38 130.1 0.3 9e-09 35.3 0.0 4.3 4 0 0 4 4 4 4 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 RLN97035.1 - 3.7e-24 86.0 3.7 8.8e-05 23.2 0.1 4.1 4 0 0 4 4 4 4 Acetyltransferase (GNAT) domain FR47 PF08445.10 RLN97035.1 - 5e-24 84.1 3.3 8.1e-05 22.5 0.0 4.4 4 0 0 4 4 4 4 FR47-like protein Acetyltransf_4 PF13420.7 RLN97035.1 - 1.7e-16 60.7 0.0 0.0014 18.8 0.0 4.5 5 0 0 5 5 4 3 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 RLN97035.1 - 4.8e-15 55.5 0.0 0.0089 16.1 0.0 4.7 4 0 0 4 4 4 4 GCN5-related N-acetyl-transferase PanZ PF12568.8 RLN97035.1 - 1.6e-12 47.2 2.5 0.037 13.8 0.0 4.5 4 0 0 4 4 4 4 Acetyltransferase (GNAT) domain, PanZ TcpQ PF10671.9 RLN97035.1 - 3.8e-09 36.5 7.3 0.44 10.7 0.1 4.4 4 0 0 4 4 4 4 Toxin co-regulated pilus biosynthesis protein Q Acetyltransf_6 PF13480.7 RLN97035.1 - 1.7e-07 31.5 1.0 0.077 13.2 0.1 5.0 4 3 0 4 4 4 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 RLN97035.1 - 9.3e-07 29.0 8.0 1.4 9.0 0.0 7.0 7 1 0 7 7 6 2 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 RLN97035.1 - 9.8e-05 22.3 6.6 9.4 6.3 0.0 4.9 4 0 0 4 4 4 0 ESCO1/2 acetyl-transferase PKS_DE PF18369.1 RLN97035.1 - 0.00062 20.3 0.0 4.6 7.9 0.0 4.1 3 0 0 3 3 3 1 Polyketide synthase dimerisation element domain OMP_b-brl PF13505.6 RLN97035.1 - 0.001 19.2 0.1 2 8.5 0.0 3.4 3 0 0 3 3 3 1 Outer membrane protein beta-barrel domain DAHP_snth_FXD PF18152.1 RLN97035.1 - 0.0058 16.4 0.1 12 5.9 0.0 3.5 3 0 0 3 3 3 0 DAHP synthase ferredoxin-like domain DIL PF01843.19 RLN97035.1 - 0.0094 16.2 0.2 1.3e+02 2.9 0.0 4.2 4 0 0 4 4 4 0 DIL domain DUF296 PF03479.15 RLN97035.1 - 0.011 16.1 0.0 19 5.7 0.0 3.6 4 0 0 4 4 4 0 Plants and Prokaryotes Conserved (PCC) domain DUF2164 PF09932.9 RLN97035.1 - 0.033 14.3 0.4 18 5.5 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2164) DUF5403 PF17395.2 RLN97035.1 - 0.035 14.4 0.0 16 5.8 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5403) PCP_red PF08369.10 RLN97035.1 - 0.038 14.2 0.0 70 3.8 0.0 3.9 4 0 0 4 4 4 0 Proto-chlorophyllide reductase 57 kD subunit DUF5331 PF17265.2 RLN97035.1 - 0.14 11.9 0.0 9.5 6.0 0.0 3.4 4 0 0 4 4 4 0 Family of unknown function (DUF5331) Peptidase_M1_N PF17900.1 RLN97035.1 - 0.16 12.2 0.0 18 5.4 0.0 2.5 2 0 0 2 2 2 0 Peptidase M1 N-terminal domain RHH_5 PF07878.11 RLN97035.1 - 1.4 8.8 9.6 44 4.1 0.1 4.3 4 0 0 4 4 4 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 Exo_endo_phos PF03372.23 RLN97038.1 - 5.2e-15 55.6 0.0 7.9e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family IQ PF00612.27 RLN97039.1 - 3.3e-08 32.6 25.9 0.0049 16.5 0.0 6.8 6 0 0 6 6 6 4 IQ calmodulin-binding motif APC_u14 PF16635.5 RLN97039.1 - 0.076 13.6 0.3 0.43 11.1 0.0 2.5 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr TPR_11 PF13414.6 RLN97040.1 - 4.6e-14 51.8 4.4 8.1e-08 31.8 0.5 2.8 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.17 RLN97040.1 - 5.4e-13 48.0 15.1 0.00011 22.0 0.3 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN97040.1 - 2.1e-12 46.3 11.8 2.1e-05 24.1 0.3 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN97040.1 - 1.8e-10 40.4 0.7 0.00012 22.2 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN97040.1 - 6.9e-07 29.0 9.3 0.097 12.9 0.2 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat DnaJ PF00226.31 RLN97040.1 - 1.7e-05 24.9 3.6 0.0002 21.5 0.7 3.5 2 1 0 2 2 2 1 DnaJ domain TPR_14 PF13428.6 RLN97040.1 - 2.5e-05 24.7 15.3 0.012 16.4 0.1 5.0 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN97040.1 - 0.004 17.6 11.5 0.011 16.2 1.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN97040.1 - 0.09 12.9 0.4 1.6 9.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TOM20_plant PF06552.12 RLN97040.1 - 0.29 10.9 12.0 1.4 8.6 0.2 2.9 3 0 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_9 PF13371.6 RLN97040.1 - 0.88 9.8 6.0 0.25 11.5 0.5 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN97040.1 - 1.8 9.3 18.9 0.2 12.3 0.6 4.1 4 1 1 5 5 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN97040.1 - 3.9 8.3 13.9 13 6.7 0.1 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat RNase_Zc3h12a PF11977.8 RLN97041.1 - 2.4e-15 56.6 0.0 5e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain KH_1 PF00013.29 RLN97041.1 - 0.0032 17.3 0.0 0.0078 16.0 0.0 1.6 1 0 0 1 1 1 1 KH domain DUF5615 PF18480.1 RLN97041.1 - 0.015 15.0 0.5 0.048 13.4 0.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5615) DUF4411 PF14367.6 RLN97041.1 - 0.035 14.0 1.3 0.053 13.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4411) PRORP PF16953.5 RLN97041.1 - 0.42 10.1 5.8 0.38 10.2 0.1 2.5 3 0 0 3 3 3 0 Protein-only RNase P WGG PF10273.9 RLN97042.1 - 5e-19 68.7 0.1 1.6e-18 67.1 0.0 1.8 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 RLN97042.1 - 0.055 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Ku PF02735.16 RLN97043.1 - 9.7e-43 146.2 0.0 1.7e-42 145.5 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 RLN97043.1 - 1e-23 83.7 0.7 5.5e-23 81.4 0.1 2.3 2 0 0 2 2 2 1 Ku C terminal domain like Ku_N PF03731.15 RLN97043.1 - 4.9e-05 23.2 0.6 4.9e-05 23.2 0.6 2.1 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 RLN97043.1 - 0.00099 19.8 0.2 0.0079 16.9 0.0 2.6 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm DUF3632 PF12311.8 RLN97043.1 - 0.038 14.4 0.6 4.1 7.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3632) V-ATPase_G PF03179.15 RLN97043.1 - 4.4 7.9 6.3 0.57 10.8 0.2 2.7 3 0 0 3 3 3 0 Vacuolar (H+)-ATPase G subunit Sugar_tr PF00083.24 RLN97044.1 - 1.2e-105 354.0 18.7 1.4e-105 353.8 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN97044.1 - 1.4e-25 90.0 29.5 9e-18 64.3 8.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RLN97044.1 - 0.00089 17.9 0.8 0.00089 17.9 0.8 3.2 3 0 0 3 3 3 2 MFS/sugar transport protein BT1 PF03092.16 RLN97044.1 - 0.015 13.5 0.2 0.015 13.5 0.2 2.0 2 0 0 2 2 2 0 BT1 family Gly-zipper_Omp PF13488.6 RLN97044.1 - 0.2 11.7 3.2 1.5 8.9 0.5 2.8 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.15 RLN97044.1 - 0.51 10.2 3.4 0.9 9.5 0.9 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain DUF3054 PF11255.8 RLN97044.1 - 9.7 6.8 11.3 1.5 9.4 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3054) VWA PF00092.28 RLN97045.1 - 2.8e-10 40.7 0.0 6.2e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RLN97045.1 - 9.7e-07 29.4 0.0 3.1e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain RHD3 PF05879.12 RLN97045.1 - 3.1e-06 25.7 1.6 3.5e-06 25.5 0.1 1.8 3 0 0 3 3 3 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 RLN97045.1 - 2.6e-05 23.6 0.1 4.7e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 RLN97045.1 - 0.0068 16.5 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 RLN97045.1 - 0.18 11.9 0.0 0.43 10.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Thioredoxin PF00085.20 RLN97047.1 - 2.7e-25 88.4 1.0 1.4e-24 86.1 0.8 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 RLN97047.1 - 1.9e-09 37.7 0.2 9.4e-06 25.6 0.3 2.8 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 RLN97047.1 - 2.6e-05 24.6 0.8 0.16 12.4 0.1 2.6 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RLN97047.1 - 0.0044 17.3 0.6 0.084 13.2 0.1 2.9 2 1 1 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.21 RLN97047.1 - 0.011 15.6 0.8 0.31 11.0 0.1 3.0 3 0 0 3 3 3 0 AhpC/TSA family Thioredoxin_7 PF13899.6 RLN97047.1 - 0.04 14.1 0.0 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like HGTP_anticodon PF03129.20 RLN97048.1 - 1.2e-19 70.2 0.0 2.4e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 RLN97048.1 - 2e-09 37.7 0.0 3.3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) MtN3_slv PF03083.16 RLN97049.1 - 8.9e-24 83.4 13.2 3.4e-19 68.6 2.3 2.9 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange DUF3961 PF13106.6 RLN97049.1 - 0.12 12.0 1.7 1.7 8.4 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3961) TMEM43 PF07787.12 RLN97049.1 - 0.47 9.8 1.7 0.96 8.8 1.7 1.5 1 0 0 1 1 1 0 Transmembrane protein 43 Pkinase_Tyr PF07714.17 RLN97050.1 - 6.3e-29 101.0 0.0 1.1e-28 100.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN97050.1 - 5.4e-24 85.0 0.0 1.1e-23 84.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RLN97050.1 - 0.0032 16.8 0.0 0.005 16.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Bac_DNA_binding PF00216.21 RLN97050.1 - 0.019 15.1 0.0 0.062 13.5 0.0 1.9 1 0 0 1 1 1 0 Bacterial DNA-binding protein DUF309 PF03745.14 RLN97050.1 - 0.099 12.3 0.6 0.25 11.1 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF309) EF-G-binding_N PF07299.11 RLN97050.1 - 0.15 12.6 2.1 0.28 11.8 0.3 2.2 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal DUF2730 PF10805.8 RLN97050.1 - 1.3 9.1 5.0 9.3 6.4 0.4 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF2730) Ank_2 PF12796.7 RLN97051.1 - 1.2e-33 115.5 1.4 1.7e-19 70.2 0.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN97051.1 - 4.3e-30 103.4 8.2 9.6e-10 38.5 0.2 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN97051.1 - 5.7e-28 96.9 0.1 2.2e-10 40.8 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN97051.1 - 2.3e-25 87.9 0.4 0.00011 22.4 0.0 5.0 4 1 1 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 RLN97051.1 - 5.2e-23 78.6 0.0 0.0003 21.0 0.0 5.4 5 1 0 5 5 5 5 Ankyrin repeat BBS2_Mid PF14783.6 RLN97051.1 - 0.015 15.3 0.1 21 5.2 0.0 3.1 2 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF3368 PF11848.8 RLN97051.1 - 0.048 13.4 0.1 4.1 7.2 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3368) GDPD_2 PF13653.6 RLN97051.1 - 0.3 11.6 2.1 73 4.0 0.0 3.4 3 0 0 3 3 3 0 Glycerophosphoryl diester phosphodiesterase family PH PF00169.29 RLN97054.1 - 0.003 18.1 0.0 0.0033 17.9 0.0 1.1 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 RLN97054.1 - 0.029 14.7 0.0 0.1 12.9 0.0 1.7 1 1 1 2 2 2 0 Pleckstrin homology domain PH_5 PF15405.6 RLN97054.1 - 0.13 12.3 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain FYVE PF01363.21 RLN97055.1 - 1.9e-12 47.1 12.5 4.1e-12 46.1 12.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger TPR_1 PF00515.28 RLN97055.1 - 1.9e-10 40.1 1.2 0.00079 19.1 0.0 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN97055.1 - 3.1e-10 39.4 1.3 0.0034 17.5 0.0 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN97055.1 - 3.8e-10 39.3 0.1 0.001 18.7 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.17 RLN97055.1 - 5.5e-09 35.5 8.6 0.0077 16.3 0.1 4.9 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN97055.1 - 1.7e-06 28.6 15.6 5e-05 23.9 0.6 4.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN97055.1 - 3.7e-06 27.4 7.7 6.1e-05 23.5 1.2 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN97055.1 - 8.8e-05 22.6 0.0 0.012 15.9 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN97055.1 - 0.00061 20.0 0.2 0.00061 20.0 0.2 4.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN97055.1 - 0.00063 19.6 0.3 0.00063 19.6 0.3 3.4 5 0 0 5 5 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN97055.1 - 0.0013 18.9 0.3 0.0039 17.4 0.3 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RLN97055.1 - 0.003 18.2 12.3 0.33 11.9 0.0 4.6 2 1 1 4 4 4 2 Tetratricopeptide repeat Vps5 PF09325.10 RLN97055.1 - 0.01 15.4 5.7 0.026 14.1 3.7 2.3 2 0 0 2 2 2 0 Vps5 C terminal like TPR_10 PF13374.6 RLN97055.1 - 0.061 13.2 0.1 0.061 13.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 RLN97055.1 - 0.16 12.7 0.1 0.16 12.7 0.1 3.7 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN97055.1 - 0.26 12.0 1.9 38 5.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 RLN97055.1 - 0.31 10.9 2.5 0.98 9.3 2.5 1.9 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal IFT57 PF10498.9 RLN97055.1 - 3.3 6.6 12.8 16 4.3 12.8 2.0 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 TPR_2 PF07719.17 RLN97056.1 - 0.018 15.1 1.0 0.018 15.1 1.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Paf67 PF10255.9 RLN97056.1 - 0.025 13.6 0.4 0.03 13.3 0.4 1.2 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 TPR_12 PF13424.6 RLN97056.1 - 0.034 14.4 0.5 0.45 10.8 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN97056.1 - 0.038 13.8 1.1 0.1 12.5 1.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4111 PF13427.6 RLN97056.1 - 0.061 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) Sigma70_r4 PF04545.16 RLN97056.1 - 0.082 12.4 0.2 0.23 11.0 0.1 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 TPR_8 PF13181.6 RLN97056.1 - 0.29 11.5 3.5 0.24 11.7 0.7 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat SANT_DAMP1_like PF16282.5 RLN97057.1 - 1.1e-13 51.1 0.4 2.1e-13 50.3 0.4 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 HSP70 PF00012.20 RLN97058.1 - 6.2e-266 883.3 14.5 7.1e-266 883.1 14.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN97058.1 - 9.4e-15 54.2 4.9 1.1e-12 47.4 0.1 3.0 3 1 0 3 3 3 2 MreB/Mbl protein DUF4795 PF16043.5 RLN97058.1 - 0.00079 19.1 2.6 0.0019 17.8 2.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) FtsA PF14450.6 RLN97058.1 - 0.0038 17.6 4.3 2.3 8.7 0.0 3.7 3 2 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 RLN97058.1 - 0.0085 15.8 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain RNA_pol_Rpb2_6 PF00562.28 RLN97058.1 - 0.014 14.5 1.5 0.028 13.5 1.5 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 Dynamin_M PF01031.20 RLN97058.1 - 0.057 12.6 0.6 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 Dynamin central region DUF4192 PF13830.6 RLN97058.1 - 0.35 10.9 5.4 0.96 9.4 5.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) LIM PF00412.22 RLN97059.1 - 3e-14 53.0 9.7 9.5e-10 38.6 2.8 5.2 3 2 2 5 5 5 3 LIM domain Med25_SD1 PF11235.8 RLN97059.1 - 0.0037 17.6 0.2 0.0053 17.1 0.2 1.2 1 0 0 1 1 1 1 Mediator complex subunit 25 synapsin 1 DA1-like PF12315.8 RLN97060.1 - 4.9e-38 130.6 0.1 2.4e-37 128.4 0.1 1.8 1 1 0 1 1 1 1 Protein DA1 Ribosomal_L4 PF00573.22 RLN97061.1 - 1.3e-39 135.9 0.8 2.1e-39 135.2 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 RLN97061.1 - 1.9e-27 95.1 0.7 1.9e-27 95.1 0.7 2.3 1 1 1 2 2 2 1 60S ribosomal protein L4 C-terminal domain Neur PF00064.18 RLN97061.1 - 0.061 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Neuraminidase Rsm1 PF08600.10 RLN97062.1 - 1.1e-05 25.4 0.5 2.9e-05 24.2 0.5 1.7 1 0 0 1 1 1 1 Rsm1-like zf-C3HC PF07967.13 RLN97062.1 - 0.0072 16.4 0.2 0.013 15.5 0.2 1.4 1 0 0 1 1 1 1 C3HC zinc finger-like RRM_1 PF00076.22 RLN97063.1 - 1.8e-16 59.7 0.0 2.8e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spectrin PF00435.21 RLN97063.1 - 0.0093 16.4 1.2 1.1 9.8 1.5 2.4 2 1 1 3 3 3 1 Spectrin repeat RRM_5 PF13893.6 RLN97063.1 - 0.0093 15.6 0.0 0.016 14.8 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HAUS-augmin3 PF14932.6 RLN97063.1 - 0.013 15.1 1.0 0.02 14.5 1.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 KASH_CCD PF14662.6 RLN97063.1 - 0.023 14.5 3.6 0.036 13.9 3.6 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 RLN97063.1 - 0.076 13.7 0.1 0.12 13.1 0.1 1.3 1 0 0 1 1 1 0 Initiation control protein YabA GPS2_interact PF15784.5 RLN97063.1 - 0.079 13.4 3.1 0.079 13.4 2.2 1.5 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF436 PF04260.12 RLN97063.1 - 0.09 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF436) GRP PF07172.11 RLN97063.1 - 8.6 7.1 14.0 0.66 10.7 7.2 2.1 2 0 0 2 2 2 0 Glycine rich protein family DMAP1 PF05499.12 RLN97064.1 - 3.3e-15 56.4 1.8 3.3e-15 56.4 1.8 1.9 2 1 0 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) SANT_DAMP1_like PF16282.5 RLN97064.1 - 1.1e-06 28.8 0.1 2.7e-06 27.5 0.1 1.8 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Tropomyosin PF00261.20 RLN97064.1 - 0.013 14.9 3.1 0.027 13.9 3.1 1.5 1 0 0 1 1 1 0 Tropomyosin Med3 PF11593.8 RLN97064.1 - 0.019 14.1 0.9 0.019 14.1 0.9 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DivIC PF04977.15 RLN97066.1 - 0.082 12.7 2.9 0.14 12.0 0.4 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 RLN97066.1 - 8.7 6.9 8.0 55 4.3 8.0 2.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Ras PF00071.22 RLN97069.1 - 2.1e-54 183.5 0.1 2.7e-54 183.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN97069.1 - 2.1e-29 102.2 0.0 3.5e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN97069.1 - 2.6e-14 53.1 0.1 3.4e-14 52.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RLN97069.1 - 1.1e-06 28.7 0.0 0.002 18.1 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RLN97069.1 - 1.2e-05 25.3 0.0 2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RLN97069.1 - 4.7e-05 23.0 0.2 0.00016 21.3 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 RLN97069.1 - 0.00096 18.6 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 RLN97069.1 - 0.001 18.4 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 RLN97069.1 - 0.0017 18.7 0.1 0.004 17.6 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 RLN97069.1 - 0.0041 17.4 0.2 0.013 15.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RLN97069.1 - 0.0057 16.8 0.0 0.019 15.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 RLN97069.1 - 0.018 14.6 0.0 0.4 10.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region FeoB_N PF02421.18 RLN97069.1 - 0.024 14.2 0.1 0.11 12.0 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 RLN97069.1 - 0.049 13.4 0.0 0.25 11.1 0.0 2.1 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 RLN97069.1 - 0.051 13.6 0.0 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RLN97069.1 - 0.057 13.7 0.1 0.54 10.5 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RLN97069.1 - 0.081 12.6 0.0 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain BDV_P40 PF06407.11 RLN97069.1 - 0.097 11.8 0.0 0.26 10.4 0.0 1.5 1 1 0 1 1 1 0 Borna disease virus P40 protein DUF676 PF05057.14 RLN97070.1 - 2.5e-21 76.2 0.0 5.1e-18 65.4 0.0 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Palm_thioest PF02089.15 RLN97070.1 - 0.0056 16.5 0.0 0.035 14.0 0.0 2.0 2 0 0 2 2 2 1 Palmitoyl protein thioesterase Abhydro_lipase PF04083.16 RLN97070.1 - 0.022 14.3 0.0 0.059 13.0 0.0 1.7 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Lipase_3 PF01764.25 RLN97070.1 - 0.066 13.1 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_5 PF12695.7 RLN97070.1 - 0.075 12.8 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family 60KD_IMP PF02096.20 RLN97071.1 - 3e-07 30.5 0.8 3.9e-07 30.1 0.8 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Fungal_KA1 PF16797.5 RLN97072.1 - 0.17 11.6 1.0 0.8 9.4 0.4 2.3 2 0 0 2 2 2 0 Fungal kinase associated-1 domain NBP1 PF08537.10 RLN97072.1 - 2.4 7.5 6.2 5.4 6.3 6.2 1.6 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 DUF16 PF01519.16 RLN97072.1 - 7.3 7.1 6.6 2 9.0 2.9 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 ABC2_membrane PF01061.24 RLN97073.1 - 5e-57 192.7 59.9 1.6e-29 102.9 18.0 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN97073.1 - 9.6e-16 58.5 0.0 1.4e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN97073.1 - 6.7e-05 22.8 0.0 0.19 11.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN97073.1 - 0.01 15.5 0.5 0.025 14.3 0.5 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN97073.1 - 0.012 15.6 0.2 0.021 14.7 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase PDR_CDR PF06422.12 RLN97073.1 - 0.027 14.4 0.0 0.027 14.4 0.0 3.2 3 0 0 3 3 3 0 CDR ABC transporter AAA_25 PF13481.6 RLN97073.1 - 0.029 13.9 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2399 PF09664.10 RLN97073.1 - 0.03 14.2 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) AAA_23 PF13476.6 RLN97073.1 - 0.057 13.9 0.5 0.095 13.2 0.5 1.2 1 0 0 1 1 1 0 AAA domain ACR_tran PF00873.19 RLN97073.1 - 0.12 9.9 3.3 0.2 9.3 3.3 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family cobW PF02492.19 RLN97073.1 - 0.14 11.7 0.1 0.22 11.1 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.7 RLN97073.1 - 1.7 7.7 52.4 0.32 10.1 19.5 2.8 2 2 0 2 2 2 0 ABC-2 family transporter protein Lig_chan PF00060.26 RLN97073.1 - 8.9 6.1 10.8 65 3.3 0.0 3.3 2 1 0 2 2 2 0 Ligand-gated ion channel FYVE PF01363.21 RLN97075.1 - 5.6e-17 61.6 6.4 1.1e-16 60.6 6.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN97075.1 - 0.024 14.9 5.6 0.024 14.9 5.6 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger PH PF00169.29 RLN97075.1 - 0.13 12.8 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 PH domain UPF0242 PF06785.11 RLN97075.1 - 0.22 11.6 5.6 0.36 10.9 5.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus OmpH PF03938.14 RLN97075.1 - 2.1 8.7 9.9 4.4 7.6 9.9 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SPRY PF00622.28 RLN97077.1 - 1.7e-12 47.5 0.1 3e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 SPRY domain tRNA-synt_1g PF09334.11 RLN97078.1 - 1.9e-56 191.5 0.0 2.7e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.20 RLN97078.1 - 2.2e-28 98.2 0.0 5.4e-28 96.9 0.0 1.7 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.22 RLN97078.1 - 8e-23 80.5 0.1 5.4e-22 77.8 0.0 2.0 1 1 1 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 RLN97078.1 - 3e-05 24.0 0.4 5.9e-05 23.1 0.4 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 RLN97078.1 - 4.1e-05 23.1 0.0 7.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 RLN97078.1 - 0.0049 15.8 0.0 0.0084 15.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (K) Pkinase PF00069.25 RLN97079.1 - 5.3e-45 153.8 0.0 6.4e-42 143.7 0.0 4.0 4 1 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97079.1 - 6.2e-44 150.2 0.0 1.5e-41 142.4 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN97079.1 - 4.5e-05 22.4 0.0 7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RLN97079.1 - 0.0052 16.7 0.1 0.022 14.7 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RLN97079.1 - 0.045 13.1 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 RLN97080.1 - 6.2e-46 156.9 0.0 7.6e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97080.1 - 2.7e-42 144.9 0.0 3.3e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Period_C PF12114.8 RLN97081.1 - 0.073 12.7 1.5 0.12 11.9 1.5 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Pkinase PF00069.25 RLN97082.1 - 4.3e-51 173.8 0.0 5.3e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97082.1 - 3.7e-45 154.2 0.0 4.8e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN97082.1 - 0.0093 15.3 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RLN97082.1 - 0.15 11.0 0.0 0.2 10.6 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 RLN97083.1 - 1.1e-53 182.4 0.0 1.4e-53 182.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97083.1 - 6.1e-43 147.0 0.0 7.8e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN97083.1 - 0.046 12.5 0.1 0.1 11.4 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 RLN97083.1 - 0.054 12.4 0.1 0.11 11.4 0.1 1.7 1 1 0 1 1 1 0 Haspin like kinase domain zf-CDGSH PF09360.10 RLN97084.1 - 5.4e-11 42.5 0.4 8.9e-11 41.8 0.4 1.4 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type MitoNEET_N PF10660.9 RLN97084.1 - 2.1e-09 37.3 0.3 2.9e-09 36.8 0.3 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus EMC3_TMCO1 PF01956.16 RLN97085.1 - 2.2e-20 73.1 14.1 6e-18 65.1 14.1 2.5 1 1 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like FYVE PF01363.21 RLN97086.1 - 4.7e-14 52.3 4.2 9.8e-14 51.3 4.2 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN97086.1 - 0.031 14.5 1.3 0.031 14.5 1.3 2.4 3 0 0 3 3 3 0 FYVE-type zinc finger FYVE PF01363.21 RLN97087.1 - 4.6e-13 49.1 4.7 1.1e-12 47.9 4.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN97087.1 - 0.0018 18.5 2.6 0.0018 18.5 2.6 1.9 2 0 0 2 2 2 1 FYVE-type zinc finger zf-B_box PF00643.24 RLN97087.1 - 2 8.7 10.3 0.36 11.0 6.0 2.1 2 0 0 2 2 2 0 B-box zinc finger Band_7 PF01145.25 RLN97088.1 - 9.2e-25 87.7 0.2 2.1e-24 86.5 0.2 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 RLN97088.1 - 0.00028 20.1 2.0 0.00039 19.6 2.0 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial DUF3255 PF11631.8 RLN97088.1 - 0.12 12.2 0.0 0.41 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3255) PI3_PI4_kinase PF00454.27 RLN97089.1 - 3e-55 187.8 0.0 5.1e-55 187.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pkinase_Tyr PF07714.17 RLN97089.1 - 8.1e-17 61.4 0.0 1.7e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN97089.1 - 3e-15 56.3 0.0 2e-14 53.6 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain FATC PF02260.20 RLN97089.1 - 9.5e-05 22.1 0.0 0.00021 21.0 0.0 1.6 1 0 0 1 1 1 1 FATC domain Metallophos_C PF14008.6 RLN97090.1 - 1.6e-10 41.7 0.1 4.3e-10 40.3 0.1 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 RLN97090.1 - 5.2e-06 26.9 0.0 1.2e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain UPF0172 PF03665.13 RLN97094.1 - 1.8e-48 165.1 0.0 2.1e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 RLN97094.1 - 0.033 14.2 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Cupin_8 PF13621.6 RLN97095.1 - 9.5e-20 71.4 0.3 1.9e-19 70.4 0.0 1.6 2 0 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 RLN97095.1 - 3.4e-19 69.4 0.0 9.9e-19 67.9 0.0 1.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase TGase_elicitor PF16683.5 RLN97096.1 - 7.8e-177 587.5 0.9 9.2e-177 587.2 0.9 1.0 1 0 0 1 1 1 1 Transglutaminase elicitor SAB PF04382.13 RLN97097.1 - 1.1 9.4 4.9 4.8 7.3 1.0 3.0 2 0 0 2 2 2 0 SAB domain GlcNAc PF11397.8 RLN97098.1 - 2.1e-46 159.0 0.0 5.1e-40 138.0 0.1 2.5 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) WD40_4 PF16300.5 RLN97101.1 - 0.068 13.1 0.6 0.14 12.1 0.6 1.5 1 0 0 1 1 1 0 Type of WD40 repeat zinc_ribbon_4 PF13717.6 RLN97102.1 - 0.16 11.9 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Peptidase_M16_M PF16187.5 RLN97103.1 - 2.7e-86 289.3 0.0 3.8e-86 288.8 0.0 1.2 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 RLN97103.1 - 1.3e-28 100.3 0.0 2.5e-17 63.5 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Glyco_hydro_72 PF03198.14 RLN97104.1 - 2.8e-06 26.8 0.0 8.8e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 Glucanosyltransferase SpoU_methylase PF00588.19 RLN97106.1 - 9.6e-17 61.5 0.2 3e-09 37.2 0.0 2.1 2 0 0 2 2 2 2 SpoU rRNA Methylase family NAD_binding_11 PF14833.6 RLN97106.1 - 0.032 14.5 0.1 0.073 13.3 0.1 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DUF1336 PF07059.12 RLN97107.1 - 2.5e-71 240.4 0.0 3.4e-71 240.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) START PF01852.19 RLN97107.1 - 0.00033 20.1 0.2 0.083 12.3 0.0 2.2 1 1 1 2 2 2 2 START domain Mucin PF01456.17 RLN97107.1 - 0.48 10.4 14.6 0.032 14.2 8.3 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein SSP160 PF06933.11 RLN97107.1 - 3.2 5.8 9.3 5.2 5.1 9.3 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Cellulase PF00150.18 RLN97108.1 - 5.4e-40 137.6 0.0 6.6e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1398 PF07166.11 RLN97108.1 - 0.21 11.7 0.1 0.36 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) DEAD PF00270.29 RLN97109.1 - 6.8e-30 104.1 0.1 1.6e-29 102.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN97109.1 - 3.7e-26 91.7 0.2 6.7e-26 90.8 0.2 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN97109.1 - 0.00071 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit fragilysinNterm PF16376.5 RLN97109.1 - 0.084 12.6 0.1 0.4 10.4 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain of fragilysin Helicase_C_2 PF13307.6 RLN97109.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain WD40 PF00400.32 RLN97110.1 - 5.2e-28 96.7 21.6 1.1e-06 29.2 0.1 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat NLE PF08154.12 RLN97110.1 - 9.8e-22 77.3 0.0 1.7e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 RLN97110.1 - 4.6e-06 25.6 4.9 0.021 13.5 0.2 3.7 1 1 1 4 4 4 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 RLN97110.1 - 4.7e-05 23.6 4.9 0.0085 16.4 0.2 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 RLN97110.1 - 0.015 14.6 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ_3 PF13570.6 RLN97110.1 - 7.4 7.2 16.5 1.2 9.8 0.9 4.8 5 2 0 5 5 5 0 PQQ-like domain UPF0193 PF05250.11 RLN97112.1 - 9.5e-06 25.6 1.4 1.1e-05 25.4 1.0 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0193) Vac_Fusion PF02346.16 RLN97112.1 - 0.011 15.4 0.2 0.81 9.4 0.0 3.0 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 YgaB PF14182.6 RLN97112.1 - 0.14 12.5 1.1 1 9.8 0.3 2.4 2 1 1 3 3 3 0 YgaB-like protein TB2_DP1_HVA22 PF03134.19 RLN97113.1 - 3.8e-13 49.2 19.7 4.2e-11 42.6 2.6 3.4 3 0 0 3 3 3 2 TB2/DP1, HVA22 family FancD2 PF14631.6 RLN97114.1 - 3.6e-33 114.2 10.4 1.5e-31 108.9 11.1 2.6 2 1 0 2 2 2 2 Fanconi anaemia protein FancD2 nuclease FancD2 PF14631.6 RLN97115.1 - 1.6e-36 125.4 1.5 2.2e-36 124.8 1.5 1.1 1 0 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease CobT PF06213.12 RLN97115.1 - 0.15 11.4 12.5 0.22 10.9 12.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Presenilin PF01080.17 RLN97115.1 - 1 8.0 9.6 0.078 11.7 4.7 1.5 2 0 0 2 2 2 0 Presenilin Nop14 PF04147.12 RLN97115.1 - 1.4 7.1 12.1 1.8 6.6 12.1 1.2 1 0 0 1 1 1 0 Nop14-like family zf-BED PF02892.15 RLN97118.1 - 0.026 14.5 0.6 0.1 12.6 0.1 2.3 2 0 0 2 2 2 0 BED zinc finger SIL1 PF16782.5 RLN97118.1 - 0.098 11.9 0.3 2.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Nucleotide exchange factor SIL1 SprT-like PF10263.9 RLN97120.1 - 0.0071 16.2 0.5 0.014 15.3 0.2 1.6 2 0 0 2 2 2 1 SprT-like family FUSC PF04632.12 RLN97120.1 - 8 4.9 7.0 14 4.1 7.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family RWP-RK PF02042.15 RLN97121.1 - 2.9e-17 62.4 0.3 5.6e-17 61.4 0.3 1.5 1 0 0 1 1 1 1 RWP-RK domain WD40 PF00400.32 RLN97122.1 - 3.5e-21 75.1 18.0 0.00019 22.1 0.1 8.5 7 2 0 7 7 7 5 WD domain, G-beta repeat RhoGAP PF00620.27 RLN97122.1 - 5e-16 58.9 0.0 8.5e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain ANAPC4_WD40 PF12894.7 RLN97122.1 - 4e-10 39.8 0.2 0.066 13.5 0.0 5.1 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 RLN97122.1 - 0.021 13.8 0.7 1.3 7.9 0.3 2.8 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain FYVE PF01363.21 RLN97123.1 - 0.00011 22.2 2.2 0.00018 21.6 2.2 1.3 1 0 0 1 1 1 1 FYVE zinc finger Glyco_hydro_18 PF00704.28 RLN97124.1 - 2.3e-28 99.8 0.0 2.9e-28 99.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Methyltr_RsmB-F PF01189.17 RLN97125.1 - 5.2e-17 62.2 0.3 1.1e-15 57.9 0.3 2.7 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Coilin_N PF15862.5 RLN97125.1 - 1.3 8.8 10.1 0.14 12.0 0.5 2.3 2 0 0 2 2 2 0 Coilin N-terminus Pox_Ag35 PF03286.14 RLN97125.1 - 1.7 8.4 14.3 0.024 14.4 5.2 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Peptidase_S49_N PF08496.10 RLN97125.1 - 5.5 7.0 8.6 17 5.4 0.4 2.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF3510 PF12022.8 RLN97125.1 - 6.6 7.1 7.8 57 4.1 0.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) DUF4470 PF14737.6 RLN97126.1 - 6.9e-23 80.7 0.0 1.3e-22 79.8 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) DUF4471 PF14740.6 RLN97126.1 - 0.06 12.6 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Ank_2 PF12796.7 RLN97128.1 - 1.8e-21 76.5 2.2 4.6e-11 43.1 0.1 3.8 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN97128.1 - 1.8e-15 57.0 5.7 6e-06 26.7 0.8 5.4 3 1 2 5 5 5 4 Ankyrin repeats (many copies) WW PF00397.26 RLN97128.1 - 9.1e-14 51.3 9.7 6.9e-07 29.2 1.3 2.7 2 0 0 2 2 2 2 WW domain Ank_5 PF13857.6 RLN97128.1 - 4.7e-12 45.9 3.9 0.069 13.5 0.1 5.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN97128.1 - 1.6e-10 40.3 9.9 0.19 12.4 0.1 6.4 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 RLN97128.1 - 2e-09 37.5 5.2 0.38 11.3 0.0 6.6 6 0 0 6 6 6 1 Ankyrin repeat Nop14 PF04147.12 RLN97129.1 - 0.83 7.8 11.7 0.97 7.6 11.7 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.7 RLN97129.1 - 3.8 5.5 8.1 4.7 5.2 8.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AIF_C PF14721.6 RLN97130.1 - 1.6e-17 64.1 0.0 6.5e-08 33.0 0.0 2.2 1 1 1 2 2 2 2 Apoptosis-inducing factor, mitochondrion-associated, C-term Kinesin PF00225.23 RLN97132.1 - 1.4e-113 379.2 0.5 2.3e-113 378.5 0.5 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN97132.1 - 5.2e-27 94.6 0.1 2.8e-26 92.2 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding ZZ PF00569.17 RLN97132.1 - 1.6e-08 34.2 1.9 1.6e-08 34.2 1.9 1.8 2 0 0 2 2 2 1 Zinc finger, ZZ type KLRAQ PF10205.9 RLN97132.1 - 0.014 15.6 0.9 0.057 13.7 0.9 2.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein XhlA PF10779.9 RLN97132.1 - 0.061 13.5 0.5 0.23 11.7 0.5 2.0 1 0 0 1 1 1 0 Haemolysin XhlA BBP1_C PF15272.6 RLN97132.1 - 0.2 11.5 6.1 0.27 11.0 3.0 2.6 3 0 0 3 3 3 0 Spindle pole body component BBP1, C-terminal CENP-F_leu_zip PF10473.9 RLN97132.1 - 0.27 11.3 13.2 0.5 10.4 9.6 2.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 RLN97132.1 - 2.1 8.8 13.0 4.5 7.7 11.2 2.6 1 1 0 1 1 1 0 Fez1 Tropomyosin_1 PF12718.7 RLN97132.1 - 2.5 8.2 17.2 1.5 9.0 14.1 2.2 2 1 0 2 2 2 0 Tropomyosin like Atg14 PF10186.9 RLN97132.1 - 3.3 6.7 9.7 1 8.4 5.7 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Peptidase_M16 PF00675.20 RLN97133.1 - 1.2e-54 184.3 0.1 1.9e-54 183.7 0.1 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 RLN97133.1 - 2e-22 80.1 0.0 4.9e-21 75.6 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain MFS_1 PF07690.16 RLN97133.1 - 1.6e-07 30.6 5.5 2.5e-07 30.0 5.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 RLN97133.1 - 0.011 14.4 3.0 0.015 13.9 3.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein MFS_1_like PF12832.7 RLN97133.1 - 0.011 14.6 0.1 0.014 14.3 0.1 1.2 1 0 0 1 1 1 0 MFS_1 like family RbsD_FucU PF05025.13 RLN97133.1 - 0.087 13.2 0.2 0.53 10.7 0.1 2.1 2 0 0 2 2 2 0 RbsD / FucU transport protein family M16C_assoc PF08367.11 RLN97133.1 - 0.099 11.8 0.2 0.21 10.7 0.2 1.5 1 0 0 1 1 1 0 Peptidase M16C associated 2OG-FeII_Oxy_3 PF13640.6 RLN97134.1 - 5.8e-09 36.7 0.0 0.00012 22.9 0.0 2.6 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Sec7 PF01369.20 RLN97136.1 - 0.051 13.2 0.3 0.068 12.8 0.3 1.1 1 0 0 1 1 1 0 Sec7 domain YtxH PF12732.7 RLN97136.1 - 0.12 12.9 4.3 0.094 13.3 2.3 1.9 2 0 0 2 2 2 0 YtxH-like protein Hormone_1 PF00103.20 RLN97136.1 - 0.16 11.7 2.0 0.22 11.3 1.7 1.4 1 1 0 1 1 1 0 Somatotropin hormone family DUF4381 PF14316.6 RLN97136.1 - 0.38 11.0 6.9 0.065 13.5 3.6 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) LSM PF01423.22 RLN97137.1 - 5.6e-09 35.6 0.1 8.8e-09 34.9 0.1 1.2 1 0 0 1 1 1 1 LSM domain Pkinase PF00069.25 RLN97138.1 - 5.7e-72 242.2 0.0 7.5e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97138.1 - 2.2e-45 155.0 0.0 3e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN97138.1 - 2.8e-05 23.6 0.0 0.00029 20.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 RLN97138.1 - 0.057 13.0 0.2 0.14 11.7 0.2 1.6 1 1 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 RLN97138.1 - 0.092 12.3 0.3 0.28 10.7 0.3 1.8 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL HHH_8 PF14716.6 RLN97139.1 - 1.7e-11 44.3 0.1 2.6e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain ERCC4 PF02732.15 RLN97140.1 - 8.6e-12 45.5 0.2 1.4e-11 44.8 0.2 1.3 1 0 0 1 1 1 1 ERCC4 domain Trypsin PF00089.26 RLN97141.1 - 7.2e-19 68.5 2.0 8e-19 68.3 2.0 1.0 1 0 0 1 1 1 1 Trypsin DUF316 PF03761.15 RLN97141.1 - 0.032 13.8 0.0 0.038 13.6 0.0 1.1 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 Trypsin PF00089.26 RLN97142.1 - 9.8e-48 162.9 0.8 1.2e-47 162.6 0.8 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 RLN97142.1 - 8.6e-08 33.2 1.5 1.4e-07 32.6 1.5 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Mito_carr PF00153.27 RLN97143.1 - 9.3e-37 124.8 5.4 8.1e-15 54.5 0.7 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein An_peroxidase PF03098.15 RLN97144.1 - 0.082 11.5 0.0 0.082 11.5 0.0 1.0 1 0 0 1 1 1 0 Animal haem peroxidase Hexapep PF00132.24 RLN97145.1 - 3.6e-10 39.2 6.9 3.7e-06 26.5 0.7 2.2 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 RLN97145.1 - 0.0016 18.2 6.7 0.16 11.8 1.0 2.7 1 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase DUF4644 PF15486.6 RLN97145.1 - 0.094 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) CDP-OH_P_transf PF01066.21 RLN97147.1 - 6.7e-16 58.8 0.4 6.7e-16 58.8 0.4 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase UbiA PF01040.18 RLN97148.1 - 7.3e-52 176.2 18.0 1e-51 175.7 18.0 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DEAD PF00270.29 RLN97149.1 - 4.9e-22 78.5 0.0 1.1e-21 77.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN97149.1 - 5.3e-12 46.1 0.0 1.5e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN97149.1 - 0.011 15.7 0.0 0.028 14.4 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Phage_attach PF05354.11 RLN97150.1 - 0.067 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Phage Head-Tail Attachment DEAD PF00270.29 RLN97152.1 - 2.7e-49 167.3 0.0 4.1e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN97152.1 - 5.1e-31 107.3 0.0 1.7e-30 105.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 RLN97152.1 - 8.8e-06 25.1 0.0 1.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 RLN97152.1 - 0.0002 21.4 0.0 0.00035 20.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RLN97152.1 - 0.094 13.0 0.6 0.37 11.1 0.6 2.1 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 RLN97153.1 - 3.8e-23 81.3 16.7 6.2e-05 23.7 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN97153.1 - 3.8e-14 52.8 0.6 8.5e-05 22.8 0.0 4.6 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RLN97153.1 - 0.00011 22.1 0.0 0.022 14.6 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 RLN97153.1 - 0.0026 16.8 0.0 0.073 12.0 0.0 2.7 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_C48 PF02902.19 RLN97154.1 - 0.009 15.9 0.0 0.018 14.9 0.0 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain U79_P34 PF03064.16 RLN97155.1 - 0.47 9.8 3.7 0.95 8.8 3.7 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4554 PF15091.6 RLN97155.1 - 7 5.4 6.8 13 4.5 6.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) DUF4672 PF15716.5 RLN97155.1 - 9.5 5.8 12.8 13 5.3 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4672) ECH_1 PF00378.20 RLN97157.1 - 6.4e-42 143.6 2.1 2.7e-34 118.6 0.0 3.1 3 0 0 3 3 3 3 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 RLN97157.1 - 0.0081 16.1 1.0 34 4.3 0.0 4.3 5 0 0 5 5 5 1 Peptidase family S49 Importin_rep_6 PF18829.1 RLN97157.1 - 0.017 15.2 0.0 3.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Importin repeat 6 DUF1400 PF07176.11 RLN97157.1 - 0.022 15.0 0.3 3.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) PLDc_2 PF13091.6 RLN97159.1 - 3.5e-17 62.5 0.0 3e-13 49.8 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 RLN97159.1 - 1.1e-08 34.9 5.2 5.4e-05 23.2 0.3 3.0 2 1 0 2 2 2 2 Phospholipase D Active site motif BRX_assoc PF16627.5 RLN97160.1 - 0.13 12.4 0.4 16 5.7 0.0 2.6 2 0 0 2 2 2 0 Unstructured region between BRX_N and BRX domain Mif2_N PF15624.6 RLN97160.1 - 0.5 11.1 4.5 0.33 11.7 2.5 1.7 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Sugar_tr PF00083.24 RLN97161.1 - 3.4e-104 349.2 25.7 3.9e-104 349.0 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN97161.1 - 1.7e-27 96.3 28.4 4.3e-22 78.5 6.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily CbtA PF09490.10 RLN97161.1 - 0.053 13.3 0.4 0.053 13.3 0.4 2.5 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtA) DUF543 PF04418.12 RLN97161.1 - 0.13 12.2 3.2 13 5.8 0.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF543) DEAD PF00270.29 RLN97162.1 - 3.8e-06 26.8 0.4 0.014 15.2 0.1 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN97162.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.8 1 1 0 1 1 1 0 Helicase conserved C-terminal domain CBS PF00571.28 RLN97162.1 - 0.057 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 CBS domain DDE_Tnp_4 PF13359.6 RLN97163.1 - 5.8e-21 74.8 0.0 8.9e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 RLN97163.1 - 5.3e-07 29.5 1.3 2.7e-06 27.2 0.0 2.5 2 1 0 2 2 2 1 Transposase DDE domain DUF755 PF05501.11 RLN97163.1 - 0.85 9.9 5.1 1.4 9.2 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) PX PF00787.24 RLN97164.1 - 2.7e-07 30.6 0.5 4.6e-06 26.6 0.0 2.9 2 1 0 2 2 2 1 PX domain SOBP PF15279.6 RLN97164.1 - 1.5 9.4 7.6 2.7 8.5 7.6 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Apc15p PF05841.11 RLN97164.1 - 6 7.7 12.9 0.12 13.1 1.4 2.8 2 1 1 3 3 3 0 Apc15p protein zf-BED PF02892.15 RLN97165.1 - 0.00047 20.1 1.7 0.00087 19.3 1.7 1.4 1 0 0 1 1 1 1 BED zinc finger DUF4064 PF13273.6 RLN97166.1 - 0.056 13.7 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Amnionless PF14828.6 RLN97166.1 - 0.12 11.2 0.5 0.17 10.6 0.5 1.2 1 0 0 1 1 1 0 Amnionless Glyco_hydro_6 PF01341.17 RLN97167.1 - 3.8e-51 174.7 1.5 3.8e-51 174.7 1.5 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 6 TMEM154 PF15102.6 RLN97167.1 - 0.00068 19.5 3.0 0.00068 19.5 3.0 2.5 1 1 1 2 2 2 1 TMEM154 protein family Presenilin PF01080.17 RLN97167.1 - 0.064 12.0 2.8 0.097 11.4 2.8 1.3 1 0 0 1 1 1 0 Presenilin BAF1_ABF1 PF04684.13 RLN97167.1 - 0.12 11.4 3.3 0.14 11.2 3.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Plasmodium_Vir PF05795.11 RLN97167.1 - 0.18 11.2 1.4 0.23 10.9 1.4 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4366 PF14283.6 RLN97167.1 - 0.77 9.8 9.9 0.033 14.2 1.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) SOG2 PF10428.9 RLN97167.1 - 1.2 8.2 19.2 1.7 7.7 19.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF966 PF06136.13 RLN97167.1 - 2.8 7.6 10.1 3.9 7.1 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) GREB1 PF15782.5 RLN97167.1 - 5.7 3.9 7.9 7.4 3.5 7.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF659 PF04937.15 RLN97168.1 - 0.0045 16.9 0.0 0.0074 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Glyco_hydro_6 PF01341.17 RLN97169.1 - 1.2e-50 173.0 0.6 1.9e-50 172.3 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Germane PF10646.9 RLN97169.1 - 0.07 13.9 0.3 0.21 12.4 0.1 2.1 2 1 0 2 2 2 0 Sporulation and spore germination Glyco_hydro_6 PF01341.17 RLN97170.1 - 8.5e-15 55.3 2.8 4.4e-13 49.6 2.0 2.5 2 1 0 2 2 2 1 Glycosyl hydrolases family 6 Casein_kappa PF00997.18 RLN97170.1 - 0.52 10.4 4.3 1.1 9.4 4.3 1.4 1 0 0 1 1 1 0 Kappa casein ADH_N PF08240.12 RLN97171.1 - 8.4e-09 35.3 0.0 1.1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ig_C17orf99 PF17736.1 RLN97171.1 - 0.16 12.0 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 C17orf99 Ig domain BT1 PF03092.16 RLN97172.1 - 3.8e-15 55.1 15.5 6.5e-10 37.9 0.6 3.4 3 1 0 3 3 3 3 BT1 family PUCC PF03209.15 RLN97172.1 - 0.00028 20.0 0.2 0.00028 20.0 0.2 2.6 3 0 0 3 3 3 1 PUCC protein PhoLip_ATPase_C PF16212.5 RLN97173.1 - 1.7e-73 247.4 10.1 1.7e-73 247.4 10.1 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RLN97173.1 - 9.6e-19 66.8 2.9 9.6e-19 66.8 2.9 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RLN97173.1 - 1.1e-11 45.5 1.0 3.2e-06 27.6 0.2 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RLN97173.1 - 9.7e-11 41.6 0.3 1e-08 35.1 0.0 3.2 3 0 0 3 3 3 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RLN97173.1 - 1.2e-06 28.1 0.0 5.8e-06 25.9 0.0 2.2 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RLN97173.1 - 0.00071 19.4 0.1 0.0016 18.3 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CDP-OH_P_tran_2 PF08009.11 RLN97173.1 - 1.7 8.6 6.9 1.3 8.9 0.8 2.8 2 0 0 2 2 2 0 CDP-alcohol phosphatidyltransferase 2 cNMP_binding PF00027.29 RLN97174.1 - 1.5e-42 143.6 3.1 9.7e-17 60.8 0.2 3.6 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain RPN13_C PF16550.5 RLN97174.1 - 0.067 13.4 0.6 0.38 10.9 0.1 2.5 2 0 0 2 2 2 0 UCH-binding domain DUF3040 PF11239.8 RLN97176.1 - 0.044 14.1 0.6 0.069 13.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DNA_pol_A PF00476.20 RLN97177.1 - 4.2e-76 256.4 0.6 6.2e-75 252.6 0.1 2.6 2 1 0 2 2 2 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 RLN97177.1 - 3.6e-11 43.1 0.0 1.1e-10 41.5 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease DUF1634 PF07843.11 RLN97178.1 - 0.065 13.3 0.3 0.065 13.3 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) Bac_rhamnosid_N PF08531.10 RLN97178.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain SDF PF00375.18 RLN97179.1 - 1.1e-70 238.7 31.6 3.4e-70 237.0 31.6 1.7 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family AsnC_trans_reg2 PF17805.1 RLN97180.1 - 0.11 12.6 0.1 0.35 11.0 0.1 1.8 1 0 0 1 1 1 0 AsnC-like ligand binding domain Cyt-b5 PF00173.28 RLN97182.1 - 1.1e-44 150.4 0.5 5.2e-10 39.3 0.0 4.3 4 0 0 4 4 4 4 Cytochrome b5-like Heme/Steroid binding domain ASL_C PF08328.11 RLN97182.1 - 0.058 13.5 0.0 0.4 10.8 0.0 2.2 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal CD36 PF01130.21 RLN97183.1 - 6e-45 153.6 0.0 1.6e-43 148.9 0.0 2.3 1 1 0 1 1 1 1 CD36 family DUF4064 PF13273.6 RLN97183.1 - 0.63 10.3 3.7 6.3 7.1 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) CD36 PF01130.21 RLN97184.1 - 6.9e-08 31.5 0.0 0.0028 16.2 0.0 2.2 1 1 0 2 2 2 2 CD36 family PCI PF01399.27 RLN97185.1 - 1.9e-15 57.2 1.2 4.3e-15 56.1 1.2 1.6 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.6 RLN97185.1 - 0.0013 18.6 2.0 3.5 7.9 0.1 4.0 5 0 0 5 5 5 2 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 RLN97185.1 - 0.085 12.8 0.3 0.2 11.6 0.3 1.6 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family TPR_14 PF13428.6 RLN97185.1 - 0.096 13.6 4.7 5.9 8.0 0.3 3.8 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN97185.1 - 0.51 10.7 3.8 7.5 6.9 1.3 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat Helicase_C_2 PF13307.6 RLN97186.1 - 7e-56 189.1 0.0 2.2e-55 187.4 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 RLN97186.1 - 2.6e-50 170.5 1.5 4.8e-50 169.6 1.5 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 RLN97186.1 - 4.6e-05 23.5 1.6 0.0073 16.3 0.2 3.6 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RLN97186.1 - 5.1e-05 23.1 0.0 0.016 15.0 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase PhoH PF02562.16 RLN97186.1 - 0.18 11.2 0.0 8 5.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein SNF2_N PF00176.23 RLN97186.1 - 0.24 10.1 1.1 0.58 8.8 1.1 1.8 1 1 0 1 1 1 0 SNF2 family N-terminal domain MFS_1 PF07690.16 RLN97187.1 - 1.8e-25 89.7 57.9 4e-17 62.2 7.5 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN97187.1 - 3.3e-13 49.3 0.3 3.3e-13 49.3 0.3 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 RLN97187.1 - 5.2e-07 28.3 21.4 0.0038 15.6 4.1 3.4 2 2 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family DUF1325 PF07039.11 RLN97188.1 - 2.8e-22 79.2 0.0 6.3e-22 78.1 0.0 1.5 2 0 0 2 2 2 1 SGF29 tudor-like domain WD40 PF00400.32 RLN97189.1 - 0.039 14.8 0.0 0.25 12.3 0.0 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat Rav1p_C PF12234.8 RLN97190.1 - 8.4e-46 156.6 0.2 7.7e-42 143.5 1.1 3.2 3 0 0 3 3 3 3 RAVE protein 1 C terminal WD40 PF00400.32 RLN97190.1 - 5.5e-06 27.0 2.3 0.0037 18.1 0.1 4.1 3 1 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN97191.1 - 6.3e-06 26.4 0.0 0.096 13.0 0.0 3.8 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RLN97191.1 - 0.00046 20.9 0.2 0.027 15.3 0.0 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat UFD1 PF03152.14 RLN97192.1 - 6.8e-27 94.0 0.0 2.7e-25 88.8 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin fusion degradation protein UFD1 Ras PF00071.22 RLN97194.1 - 1.3e-26 93.1 0.0 1.8e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN97194.1 - 1.2e-05 25.5 0.7 2.2e-05 24.7 0.1 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Zein-binding PF04576.15 RLN97195.1 - 0.0081 16.4 0.2 0.015 15.6 0.2 1.4 1 0 0 1 1 1 1 Zein-binding FRQ PF09421.10 RLN97195.1 - 0.018 13.1 0.5 0.023 12.7 0.5 1.1 1 0 0 1 1 1 0 Frequency clock protein Vps39_2 PF10367.9 RLN97196.1 - 3.2e-29 101.5 0.1 4.8e-29 101.0 0.1 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 RLN97196.1 - 0.02 14.8 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 Region in Clathrin and VPS DUF717 PF05338.12 RLN97196.1 - 0.077 13.1 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF717) EamA PF00892.20 RLN97197.1 - 9.5e-15 55.0 33.1 1.6e-07 31.6 9.1 2.4 2 0 0 2 2 2 2 EamA-like transporter family NTP_transf_3 PF12804.7 RLN97197.1 - 7e-07 29.7 0.0 4.1e-06 27.2 0.0 2.4 2 0 0 2 2 2 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 RLN97197.1 - 0.00015 21.4 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase DUF3938 PF13074.6 RLN97197.1 - 0.16 12.3 0.8 0.96 9.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) Cluap1 PF10234.9 RLN97199.1 - 0.057 12.8 0.5 0.19 11.1 0.4 1.9 1 1 1 2 2 2 0 Clusterin-associated protein-1 Lectin_N PF03954.14 RLN97200.1 - 0.018 14.8 0.9 0.029 14.1 0.9 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Na_trans_assoc PF06512.13 RLN97200.1 - 0.11 12.8 17.5 0.14 12.4 17.5 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated BT1 PF03092.16 RLN97201.1 - 9.1e-10 37.4 7.6 1.4e-08 33.5 0.7 3.2 4 0 0 4 4 4 2 BT1 family Sigma70_ECF PF07638.11 RLN97202.1 - 0.19 11.6 3.3 0.31 10.9 0.7 2.1 2 0 0 2 2 2 0 ECF sigma factor HTH_Tnp_Tc5 PF03221.16 RLN97203.1 - 3.8e-10 39.6 0.0 1.7e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 RLN97203.1 - 2.3e-06 27.2 0.9 4.6e-06 26.2 0.9 1.5 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 RLN97204.1 - 2.1e-14 53.3 1.0 3.9e-12 46.0 0.0 3.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 RLN97204.1 - 0.0011 18.6 0.4 0.0025 17.5 0.4 1.6 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_32 PF13565.6 RLN97204.1 - 0.011 16.3 0.7 0.011 16.3 0.7 3.2 3 0 0 3 3 3 0 Homeodomain-like domain CENP-B_N PF04218.13 RLN97204.1 - 0.027 14.1 0.7 0.19 11.4 0.7 2.3 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain DMAP_binding PF06464.11 RLN97204.1 - 0.1 13.4 0.2 0.25 12.2 0.2 1.7 1 0 0 1 1 1 0 DMAP1-binding Domain Thymopoietin PF08198.11 RLN97204.1 - 0.26 10.9 0.8 22 4.7 0.0 3.2 3 0 0 3 3 3 0 Thymopoietin protein NAM-associated PF14303.6 RLN97204.1 - 0.79 10.4 4.6 0.76 10.5 3.1 1.6 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain MMS1_N PF10433.9 RLN97206.1 - 5.6e-107 358.4 0.0 1e-106 357.5 0.0 1.4 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 RLN97206.1 - 6.4e-78 262.3 0.0 3.3e-77 259.9 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region PQQ_2 PF13360.6 RLN97206.1 - 0.047 13.3 0.1 11 5.5 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain MxiM PF11441.8 RLN97206.1 - 0.14 12.4 0.2 11 6.4 0.1 2.7 2 0 0 2 2 2 0 Pilot protein MxiM Rb_C PF08934.10 RLN97207.1 - 0.02 14.7 2.2 0.02 14.7 2.2 1.6 2 0 0 2 2 2 0 Rb C-terminal domain Spore_III_AB PF09548.10 RLN97207.1 - 1.8 8.6 6.3 12 6.0 3.4 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_4 PF13837.6 RLN97209.1 - 0.0025 18.2 0.3 0.0025 18.2 0.3 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain zf-MYND PF01753.18 RLN97210.1 - 1.1e-09 38.2 11.4 2.2e-09 37.3 11.4 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 RLN97210.1 - 0.00028 21.1 11.1 0.00052 20.2 11.1 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding Transp_Tc5_C PF04236.15 RLN97210.1 - 0.0047 17.3 0.6 0.0097 16.2 0.6 1.5 1 0 0 1 1 1 1 Tc5 transposase C-terminal domain DUF3846 PF12957.7 RLN97210.1 - 0.13 12.6 0.0 0.33 11.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3846) zf-HIT PF04438.16 RLN97210.1 - 0.17 11.8 10.3 0.32 10.9 10.3 1.4 1 0 0 1 1 1 0 HIT zinc finger zf-C2H2_3 PF13878.6 RLN97210.1 - 0.23 11.3 5.2 0.45 10.4 5.2 1.5 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO PutA_N PF18083.1 RLN97210.1 - 0.23 11.5 1.1 0.45 10.6 0.0 1.9 2 0 0 2 2 2 0 Proline utilization A N-terminal domain TK PF00265.18 RLN97211.1 - 1.7e-16 60.6 0.6 1.9e-16 60.4 0.6 1.1 1 0 0 1 1 1 1 Thymidine kinase DUF370 PF04025.12 RLN97211.1 - 0.15 12.2 0.0 0.53 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF370) HECT PF00632.25 RLN97212.1 - 4.2e-63 213.7 0.0 5.3e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4813 PF16072.5 RLN97212.1 - 0.49 10.0 6.6 0.82 9.3 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DUF2681 PF10883.8 RLN97214.1 - 0.0031 17.9 1.3 0.0043 17.4 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) Protocadherin PF08374.11 RLN97214.1 - 0.0068 16.4 0.1 0.0077 16.2 0.1 1.1 1 0 0 1 1 1 1 Protocadherin EphA2_TM PF14575.6 RLN97214.1 - 0.0099 16.7 0.1 0.016 16.1 0.1 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF2615 PF11027.8 RLN97214.1 - 0.026 14.7 0.0 0.036 14.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) DUF5385 PF17359.2 RLN97214.1 - 0.032 13.8 2.4 0.048 13.2 1.4 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5385) Shisa PF13908.6 RLN97214.1 - 0.082 13.1 0.0 0.09 13.0 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator LapA_dom PF06305.11 RLN97214.1 - 0.094 12.5 0.4 0.15 11.9 0.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain FixQ PF05545.11 RLN97214.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ TMEM132D_C PF15706.5 RLN97214.1 - 0.16 11.8 1.3 0.45 10.3 0.8 1.9 1 1 1 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term WD40 PF00400.32 RLN97215.1 - 5.6e-23 80.8 11.8 1.2e-05 26.0 0.0 8.7 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN97215.1 - 1.5e-05 25.2 0.0 0.74 10.2 0.0 4.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN97215.1 - 0.0026 16.8 0.1 0.017 14.1 0.0 2.2 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein SET PF00856.28 RLN97216.1 - 3.1e-20 73.2 0.1 1.7e-19 70.9 0.1 2.1 1 1 0 1 1 1 1 SET domain Vmethyltransf PF01660.17 RLN97218.1 - 0.16 10.8 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Viral methyltransferase Peroxidase_2 PF01328.17 RLN97220.1 - 2.6e-53 181.4 0.0 3e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 EamA PF00892.20 RLN97221.1 - 1.6e-23 83.4 50.9 1.4e-12 47.9 4.6 4.4 4 1 0 4 4 4 3 EamA-like transporter family Nuc_sug_transp PF04142.15 RLN97221.1 - 4.2e-07 29.5 11.7 0.0023 17.2 1.0 2.7 3 0 0 3 3 3 2 Nucleotide-sugar transporter B12D PF06522.11 RLN97221.1 - 0.063 13.1 1.8 16 5.4 0.0 3.7 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit ASFV_L11L PF05293.11 RLN97221.1 - 0.12 12.7 6.6 0.16 12.3 0.2 3.6 3 1 0 3 3 3 0 African swine fever virus (ASFV) L11L protein SLC35F PF06027.12 RLN97221.1 - 0.51 9.8 25.5 0.45 10.0 4.2 2.2 2 0 0 2 2 2 0 Solute carrier family 35 EamA PF00892.20 RLN97222.1 - 3.6e-12 46.6 3.0 3.6e-12 46.6 3.0 2.2 2 0 0 2 2 2 1 EamA-like transporter family Nuc_sug_transp PF04142.15 RLN97222.1 - 0.0028 16.9 1.6 0.0047 16.1 1.6 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 RLN97222.1 - 0.0099 15.3 7.2 0.015 14.6 7.2 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family Multi_Drug_Res PF00893.19 RLN97222.1 - 0.93 10.2 6.8 0.16 12.7 0.6 2.7 3 0 0 3 3 3 0 Small Multidrug Resistance protein TMEM234 PF10639.9 RLN97222.1 - 2.4 8.2 8.2 1.7 8.7 1.7 2.4 2 0 0 2 2 2 0 Putative transmembrane family 234 CDC24_OB2 PF17245.2 RLN97223.1 - 1.4e-20 74.2 0.0 3.7e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 2 RabGAP-TBC PF00566.18 RLN97223.1 - 1.2e-11 44.6 0.0 4e-08 33.2 0.0 2.6 2 0 0 2 2 2 2 Rab-GTPase-TBC domain CDC24_OB3 PF17244.2 RLN97223.1 - 2e-10 40.8 0.0 2e-09 37.5 0.0 2.3 2 0 0 2 2 2 1 Cell division control protein 24, OB domain 3 CDC24_OB1 PF17246.2 RLN97223.1 - 8.2e-08 32.4 0.0 2.3e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 1 FoP_duplication PF13865.6 RLN97224.1 - 0.79 10.3 10.8 5.6 7.6 8.1 2.7 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 PhyH PF05721.13 RLN97225.1 - 1e-54 186.0 0.1 1.3e-54 185.7 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 RLN97225.1 - 0.079 11.7 0.0 0.36 9.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) Ndc80_HEC PF03801.13 RLN97225.1 - 0.13 11.9 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 HEC/Ndc80p family Wyosine_form PF08608.12 RLN97225.1 - 0.14 12.6 0.2 0.8 10.1 0.0 2.1 2 0 0 2 2 2 0 Wyosine base formation Pkinase_Tyr PF07714.17 RLN97226.1 - 3.1e-07 29.9 0.0 0.0076 15.6 0.0 3.7 2 1 1 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 RLN97226.1 - 0.0042 16.5 0.0 0.61 9.4 0.0 3.2 3 1 0 3 3 3 2 Protein kinase domain Ank_2 PF12796.7 RLN97228.1 - 4.8e-125 408.4 8.9 8.5e-15 55.1 0.3 12.1 5 4 8 13 13 13 13 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN97228.1 - 6.6e-107 348.2 28.0 4.7e-11 42.7 0.0 13.3 8 3 5 14 14 14 13 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN97228.1 - 2.2e-105 343.8 21.8 3.8e-13 49.7 0.1 17.1 6 4 13 19 19 19 19 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN97228.1 - 4.9e-93 293.8 8.4 4.4e-06 26.6 0.0 21.4 23 0 0 23 23 23 15 Ankyrin repeat Ank PF00023.30 RLN97228.1 - 2.1e-89 290.4 11.9 1.4e-06 28.5 0.1 19.8 20 2 1 21 21 21 16 Ankyrin repeat HOOK PF05622.12 RLN97228.1 - 9.8e-18 63.7 0.0 9.8e-18 63.7 0.0 1.7 2 0 0 2 2 2 1 HOOK protein Nfu_N PF08712.11 RLN97229.1 - 7.4e-30 102.8 0.0 1.5e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 RLN97229.1 - 3.6e-25 87.9 0.0 6e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain SMP_LBD PF17047.5 RLN97230.1 - 4.4e-05 23.0 0.0 7.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain PH PF00169.29 RLN97230.1 - 0.00056 20.4 0.3 0.00092 19.7 0.3 1.4 1 0 0 1 1 1 1 PH domain Myb_DNA-binding PF00249.31 RLN97231.1 - 1.2e-39 134.3 9.2 4.1e-14 52.5 0.2 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN97231.1 - 1.4e-28 99.0 1.0 7.7e-13 48.5 0.0 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RLN97231.1 - 1.3e-05 25.0 0.5 8.7e-05 22.3 0.1 2.2 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 RLN97231.1 - 0.0066 16.5 0.0 0.5 10.4 0.0 2.7 1 1 2 3 3 3 1 SLIDE Kelch_4 PF13418.6 RLN97232.1 - 2.8e-36 123.3 10.1 1e-09 38.2 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN97232.1 - 2.2e-31 107.3 0.0 4.3e-07 29.8 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RLN97232.1 - 1.5e-28 98.1 1.3 8.4e-05 22.7 0.0 6.1 5 1 1 6 6 6 5 Kelch motif Kelch_3 PF13415.6 RLN97232.1 - 2e-26 91.7 19.1 1.5e-07 31.5 0.1 7.6 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 RLN97232.1 - 6.1e-26 89.4 9.0 2.2e-08 33.7 0.3 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 RLN97232.1 - 2.3e-22 78.3 5.9 3.3e-09 36.2 0.4 6.5 6 0 0 6 6 6 4 Kelch motif TFIIF_alpha PF05793.12 RLN97232.1 - 5.6 5.4 32.5 12 4.3 32.5 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GHL5 PF14872.6 RLN97233.1 - 0.21 9.6 1.2 0.24 9.4 1.2 1.1 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 CcdA PF07362.12 RLN97236.1 - 0.34 11.4 0.1 0.34 11.4 0.1 2.2 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA R3H PF01424.22 RLN97237.1 - 8.8e-15 54.5 0.1 1.6e-14 53.6 0.1 1.5 1 0 0 1 1 1 1 R3H domain SUZ PF12752.7 RLN97237.1 - 8.7e-11 42.4 1.8 8.7e-11 42.4 1.8 2.8 2 1 1 3 3 3 1 SUZ domain Hist_deacetyl PF00850.19 RLN97238.1 - 4.9e-17 62.4 0.5 8e-11 42.0 0.5 2.2 1 1 1 2 2 2 2 Histone deacetylase domain Trm112p PF03966.16 RLN97240.1 - 1.1e-05 25.9 0.0 2.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Trm112p-like protein zf-RING_2 PF13639.6 RLN97241.1 - 1.4e-10 41.3 11.3 3.4e-10 40.1 11.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RLN97241.1 - 6.7e-08 32.7 9.6 1.9e-07 31.3 9.6 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RLN97241.1 - 3.8e-07 29.9 7.0 8.6e-07 28.7 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 RLN97241.1 - 3.9e-07 30.1 0.0 1.1e-06 28.6 0.0 1.7 2 0 0 2 2 2 1 PX domain zf-C3HC4_2 PF13923.6 RLN97241.1 - 8.7e-07 28.7 7.8 2.9e-06 27.0 7.8 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN97241.1 - 2.7e-06 27.0 3.2 7e-06 25.7 3.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 RLN97241.1 - 6e-06 26.2 5.4 1.5e-05 24.9 5.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 RLN97241.1 - 8.6e-06 25.7 2.7 2.4e-05 24.3 2.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RLN97241.1 - 0.00045 20.0 8.0 0.00092 19.0 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN97241.1 - 0.0017 18.3 8.5 0.0038 17.1 8.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain RINGv PF12906.7 RLN97241.1 - 0.024 14.8 7.0 0.058 13.5 7.0 1.7 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 RLN97241.1 - 0.045 13.9 9.5 0.058 13.6 8.0 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain FERM_F2 PF18377.1 RLN97241.1 - 0.15 12.0 1.6 24 4.9 0.1 3.0 2 1 1 3 3 3 0 FERM F2 acyl-CoA binding protein-like domain Zn_ribbon_17 PF17120.5 RLN97241.1 - 1.3 8.7 9.4 4.3 7.0 9.4 1.9 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type ABM PF03992.16 RLN97242.1 - 1.9e-06 27.9 0.5 0.022 14.8 0.0 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase KilA-N PF04383.13 RLN97242.1 - 0.19 11.6 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 KilA-N domain SHQ1 PF04925.15 RLN97243.1 - 2.3e-55 186.9 0.1 3.8e-55 186.2 0.1 1.4 1 0 0 1 1 1 1 SHQ1 protein RRN3 PF05327.11 RLN97243.1 - 0.0052 15.4 3.4 0.01 14.4 3.4 1.4 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 IQ PF00612.27 RLN97243.1 - 0.39 10.6 15.2 1.3 9.0 1.3 3.8 3 0 0 3 3 3 0 IQ calmodulin-binding motif FemAB PF02388.16 RLN97243.1 - 1.3 7.8 7.6 2.3 7.0 7.6 1.4 1 0 0 1 1 1 0 FemAB family AAA PF00004.29 RLN97244.1 - 2.9e-37 128.0 0.0 4.9e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 RLN97244.1 - 4.1e-07 29.9 0.5 7.9e-07 28.9 0.5 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 RLN97244.1 - 7.6e-07 29.2 0.0 2.4e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RLN97244.1 - 1.7e-06 28.2 0.0 5.3e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 RLN97244.1 - 4.2e-06 27.2 0.0 9.6e-05 22.8 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RLN97244.1 - 1.6e-05 25.2 0.4 0.0077 16.5 0.0 3.0 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 RLN97244.1 - 6e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RLN97244.1 - 0.0013 18.9 0.2 0.0035 17.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 RLN97244.1 - 0.0021 17.8 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 RLN97244.1 - 0.0027 17.0 0.0 0.0056 15.9 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activat PF00158.26 RLN97244.1 - 0.0028 17.4 0.1 0.038 13.7 0.1 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 RLN97244.1 - 0.0048 16.3 0.0 0.012 15.0 0.1 1.6 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RLN97244.1 - 0.0049 16.7 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 RLN97244.1 - 0.0054 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RLN97244.1 - 0.006 17.1 0.4 0.023 15.3 0.0 2.1 2 1 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 RLN97244.1 - 0.011 16.1 0.0 0.025 15.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase RILP PF11461.8 RLN97244.1 - 0.012 15.8 1.6 0.023 14.9 1.6 1.5 1 0 0 1 1 1 0 Rab interacting lysosomal protein DUF815 PF05673.13 RLN97244.1 - 0.013 14.7 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 RLN97244.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_13 PF13166.6 RLN97244.1 - 0.015 14.0 0.1 0.8 8.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 RLN97244.1 - 0.016 15.3 0.0 0.072 13.1 0.0 2.1 3 0 0 3 3 3 0 AAA domain Parvo_NS1 PF01057.17 RLN97244.1 - 0.018 14.1 0.0 0.056 12.5 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 RLN97244.1 - 0.021 14.6 0.2 0.054 13.2 0.0 1.9 2 1 1 3 3 2 0 AAA domain PhoH PF02562.16 RLN97244.1 - 0.023 14.2 0.2 0.11 12.0 0.0 2.2 3 0 0 3 3 2 0 PhoH-like protein AAA_7 PF12775.7 RLN97244.1 - 0.024 14.1 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 RLN97244.1 - 0.026 13.9 0.0 0.075 12.4 0.0 1.8 2 0 0 2 2 1 0 KaiC RsgA_GTPase PF03193.16 RLN97244.1 - 0.03 14.2 0.0 0.078 12.9 0.0 1.7 2 0 0 2 2 1 0 RsgA GTPase HR1 PF02185.16 RLN97244.1 - 0.031 14.4 3.7 0.068 13.3 3.7 1.6 1 0 0 1 1 1 0 Hr1 repeat AAA_11 PF13086.6 RLN97244.1 - 0.031 14.1 0.1 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 RLN97244.1 - 0.043 13.4 0.1 0.12 11.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain DASH_Dad2 PF08654.10 RLN97244.1 - 0.049 14.0 0.4 0.14 12.6 0.5 1.6 2 0 0 2 2 1 0 DASH complex subunit Dad2 Tropomyosin PF00261.20 RLN97244.1 - 0.057 12.8 1.8 0.092 12.1 1.8 1.2 1 0 0 1 1 1 0 Tropomyosin AAA_19 PF13245.6 RLN97244.1 - 0.063 13.6 0.2 0.34 11.3 0.1 2.3 3 0 0 3 3 1 0 AAA domain Zeta_toxin PF06414.12 RLN97244.1 - 0.077 12.3 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF16 PF01519.16 RLN97244.1 - 0.087 13.3 0.4 0.6 10.6 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF4618 PF15397.6 RLN97244.1 - 0.11 12.0 2.7 0.16 11.3 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF2075 PF09848.9 RLN97244.1 - 0.13 11.5 0.1 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 RLN97244.1 - 0.13 12.3 0.0 0.42 10.7 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 RLN97244.1 - 0.14 12.6 0.1 0.85 10.1 0.0 2.1 2 0 0 2 2 2 0 ABC transporter DUF2072 PF09845.9 RLN97244.1 - 0.17 12.1 0.4 0.29 11.4 0.4 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein SlyX PF04102.12 RLN97244.1 - 0.6 10.8 4.8 0.27 11.9 2.0 1.9 2 0 0 2 2 1 0 SlyX TolA_bind_tri PF16331.5 RLN97244.1 - 4.2 7.5 10.1 2.1 8.5 6.3 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation DnaJ_C PF01556.18 RLN97245.1 - 9.8e-39 132.8 0.1 1.3e-38 132.4 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RLN97245.1 - 3.8e-24 84.6 3.9 6.1e-24 83.9 3.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 RLN97245.1 - 4.9e-14 52.4 15.6 8.6e-14 51.7 15.6 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 RLN97245.1 - 1.5e-05 24.8 17.9 0.00064 19.6 5.6 2.5 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 RLN97245.1 - 0.028 14.4 1.4 0.028 14.4 1.4 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF573 PF04504.14 RLN97245.1 - 0.23 12.1 1.8 0.23 12.1 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF573 BRE1 PF08647.11 RLN97246.1 - 6.8e-07 29.3 9.8 6.8e-07 29.3 9.8 9.3 4 2 7 11 11 11 2 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 RLN97246.1 - 0.0046 17.2 18.5 0.0046 17.2 18.5 8.1 1 1 4 7 7 7 4 Autophagy protein 16 (ATG16) CENP-B_dimeris PF09026.10 RLN97246.1 - 0.035 14.5 11.5 0.11 12.9 11.5 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 RLN97246.1 - 1.1 8.5 9.9 4.1 6.6 9.9 1.9 1 0 0 1 1 1 0 NOA36 protein PI_PP_I PF18363.1 RLN97246.1 - 7.4 6.8 12.3 3.4 7.9 1.2 5.0 3 2 2 5 5 5 0 Phosphoinositide phosphatase insertion domain DUF2333 PF10095.9 RLN97247.1 - 0.07 12.1 0.5 0.14 11.1 0.5 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) Utp12 PF04003.12 RLN97248.1 - 1.3e-19 70.5 2.0 1.3e-19 70.5 2.0 1.9 2 0 0 2 2 2 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 RLN97248.1 - 1.2e-08 35.1 0.1 3.1e-05 24.2 0.0 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 RLN97248.1 - 0.00013 21.6 3.1 0.00029 20.5 3.1 1.7 1 0 0 1 1 1 1 PQQ-like domain WD40 PF00400.32 RLN97248.1 - 0.0038 18.0 0.3 2.8 8.9 0.0 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat RRM_1 PF00076.22 RLN97249.1 - 1.9e-14 53.2 0.0 2.8e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 RLN97249.1 - 0.021 14.9 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 Ion_trans PF00520.31 RLN97250.1 - 3.4e-207 684.7 65.8 3e-56 190.4 12.7 4.2 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 RLN97250.1 - 2.7e-26 92.3 68.3 2.6e-10 39.6 8.0 9.9 7 3 3 10 10 10 8 Polycystin cation channel GPHH PF16905.5 RLN97250.1 - 1.4e-09 37.6 0.0 3.2e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated DUF2621 PF11084.8 RLN97250.1 - 0.053 13.5 0.2 16 5.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2621) PDZ PF00595.24 RLN97251.1 - 7e-06 26.3 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RLN97251.1 - 0.0059 16.4 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RLN97251.1 - 0.17 12.2 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 PDZ domain DUF3431 PF11913.8 RLN97251.1 - 0.19 11.5 0.0 5.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3431) TTL PF03133.15 RLN97252.1 - 1.5e-38 132.7 0.0 4e-34 118.1 0.0 3.0 3 0 0 3 3 3 3 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RLN97252.1 - 1.2e-06 28.0 0.2 0.0083 15.4 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RLN97252.1 - 0.19 10.9 0.0 0.59 9.3 0.0 1.7 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp MFS_1_like PF12832.7 RLN97253.1 - 9.3e-41 139.9 5.9 1.1e-40 139.7 5.9 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RLN97253.1 - 1.2e-13 50.7 31.0 3.1e-08 32.9 13.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 RLN97253.1 - 8.5e-07 28.1 2.3 1.1e-06 27.7 2.3 1.2 1 0 0 1 1 1 1 LacY proton/sugar symporter MFS_3 PF05977.13 RLN97253.1 - 0.00013 20.5 2.6 0.00016 20.2 2.6 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector Nuc_H_symport PF03825.16 RLN97253.1 - 0.00057 19.0 6.3 0.00072 18.6 6.3 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter PUCC PF03209.15 RLN97253.1 - 0.00081 18.5 0.8 0.00081 18.5 0.8 2.0 2 0 0 2 2 2 1 PUCC protein Caveolin PF01146.17 RLN97253.1 - 3.8 7.5 5.9 2.3 8.2 0.2 2.7 3 0 0 3 3 3 0 Caveolin RNase_PH PF01138.21 RLN97254.1 - 5.4e-18 65.8 0.2 4.4e-17 62.8 0.1 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RLN97254.1 - 1.2e-14 54.1 0.1 2e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 MFS_1_like PF12832.7 RLN97257.1 - 1.2e-64 218.6 18.1 4.6e-64 216.7 18.1 1.7 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RLN97257.1 - 9.2e-25 87.3 53.1 6.6e-19 68.0 29.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 RLN97257.1 - 1.5e-14 53.8 20.1 3.9e-14 52.4 20.1 1.6 1 1 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 RLN97257.1 - 4.9e-13 48.6 16.7 1.5e-12 47.0 16.7 1.9 1 1 0 1 1 1 1 LacY proton/sugar symporter MFS_3 PF05977.13 RLN97257.1 - 0.019 13.4 17.0 0.002 16.6 11.9 1.8 2 1 0 2 2 2 0 Transmembrane secretion effector UFD1 PF03152.14 RLN97258.1 - 1.8e-33 115.5 0.0 2.7e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 UBX PF00789.20 RLN97258.1 - 2.3e-14 53.3 0.0 5.1e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 UBX domain ABC_membrane PF00664.23 RLN97262.1 - 1e-28 100.8 18.5 1.3e-28 100.5 18.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN97262.1 - 1.1e-07 32.5 0.1 2.3e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 RLN97262.1 - 0.003 16.8 0.1 0.0056 16.0 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 RLN97262.1 - 0.0079 16.1 2.1 0.0091 15.9 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 RLN97262.1 - 0.0086 16.1 0.1 0.024 14.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 RLN97262.1 - 0.019 15.1 0.3 0.034 14.2 0.3 1.4 1 0 0 1 1 1 0 Dynamin family AAA_29 PF13555.6 RLN97262.1 - 0.041 13.6 0.1 0.091 12.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 RLN97262.1 - 0.078 13.1 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RLN97262.1 - 0.089 12.3 0.1 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 RLN97262.1 - 0.15 11.2 0.2 0.39 9.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Methyltransf_25 PF13649.6 RLN97263.1 - 9.8e-16 58.3 0.0 2.3e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN97263.1 - 4.1e-14 52.7 0.0 5.8e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN97263.1 - 1.4e-13 51.4 0.0 2.3e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN97263.1 - 1.4e-13 51.0 0.0 1.9e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN97263.1 - 7.1e-12 45.8 0.0 1.6e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RLN97263.1 - 1.7e-06 27.7 0.0 3.7e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 RLN97263.1 - 8.5e-05 22.0 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.18 RLN97263.1 - 0.00056 19.5 0.0 0.067 12.7 0.0 2.2 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain ImpE PF07024.13 RLN97263.1 - 0.036 14.1 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 ImpE protein Methyltransf_28 PF02636.17 RLN97263.1 - 0.096 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Glyco_hydro_1 PF00232.18 RLN97266.1 - 3.7e-143 477.2 0.6 4.1e-143 477.1 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 ADH_zinc_N_2 PF13602.6 RLN97267.1 - 8.7e-12 46.2 0.0 7.2e-11 43.3 0.0 2.4 3 1 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 RLN97267.1 - 1e-11 44.9 0.8 1.9e-11 44.1 0.0 1.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN97267.1 - 7e-09 35.5 0.0 2.3e-08 33.9 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_16 PF10294.9 RLN97267.1 - 0.0031 17.3 0.1 0.0056 16.4 0.1 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Eno-Rase_NADH_b PF12242.8 RLN97267.1 - 0.012 15.3 0.3 0.024 14.4 0.3 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PIP5K PF01504.18 RLN97268.1 - 5.9e-68 229.1 0.0 1.2e-67 228.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_2 PF00002.24 RLN97268.1 - 0.0016 17.8 7.4 0.0042 16.4 4.5 2.2 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Phage_holin_3_6 PF07332.11 RLN97268.1 - 0.087 12.9 5.5 6.7 6.8 1.8 2.7 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III zinc_ribbon_4 PF13717.6 RLN97268.1 - 0.73 9.8 2.6 0.63 10.0 0.4 2.0 2 0 0 2 2 2 0 zinc-ribbon domain DUF2207 PF09972.9 RLN97268.1 - 1.3 7.7 6.3 4.2 6.0 0.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Ank_2 PF12796.7 RLN97269.1 - 1e-48 163.8 3.0 2.6e-15 56.8 0.1 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN97269.1 - 2.3e-25 88.3 2.4 1.4e-08 34.9 0.1 4.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RLN97269.1 - 5.8e-25 86.6 0.8 6.8e-06 26.3 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 RLN97269.1 - 1.5e-21 76.5 0.1 4.3e-09 36.7 0.0 3.9 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN97269.1 - 7.9e-19 65.8 0.0 0.00096 19.4 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat YfmQ PF10787.9 RLN97269.1 - 0.016 15.0 0.0 0.99 9.2 0.0 2.3 1 1 1 2 2 2 0 Uncharacterised protein from bacillus cereus group DUF3851 PF12962.7 RLN97270.1 - 0.12 12.6 0.4 0.24 11.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3851) GST_N_2 PF13409.6 RLN97271.1 - 1.1e-15 57.7 0.0 3.6e-15 56.0 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN97271.1 - 6.8e-13 48.4 0.1 2e-12 46.9 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RLN97271.1 - 5.8e-08 32.8 0.0 9.3e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RLN97271.1 - 9.1e-07 29.0 0.0 1.7e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 RLN97271.1 - 0.00071 19.3 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RLN97271.1 - 0.0015 18.9 0.0 0.34 11.3 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain AAA PF00004.29 RLN97272.1 - 3.9e-90 299.1 0.0 8.2e-44 149.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RLN97272.1 - 1.7e-19 69.4 13.0 4e-10 39.3 4.3 3.2 3 0 0 3 3 2 2 AAA+ lid domain RuvB_N PF05496.12 RLN97272.1 - 2.3e-12 47.0 0.0 2.9e-06 27.1 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RLN97272.1 - 9.4e-12 45.1 0.1 2e-06 27.8 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RLN97272.1 - 1.2e-10 42.1 14.3 1.7e-06 28.5 0.4 5.9 2 1 1 4 4 4 2 AAA ATPase domain TIP49 PF06068.13 RLN97272.1 - 1.5e-09 37.6 0.0 0.00035 19.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 RLN97272.1 - 1.7e-08 34.7 0.1 0.00034 20.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RLN97272.1 - 4.5e-08 33.5 0.3 0.00057 20.2 0.1 4.4 2 2 1 3 3 3 1 AAA domain AAA_2 PF07724.14 RLN97272.1 - 5.1e-08 33.2 0.0 0.017 15.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 RLN97272.1 - 1.8e-06 28.3 0.0 0.015 15.7 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Rad17 PF03215.15 RLN97272.1 - 3.2e-06 27.2 0.0 0.0043 17.0 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_25 PF13481.6 RLN97272.1 - 9.3e-06 25.3 2.8 0.19 11.3 0.1 4.1 2 2 2 4 4 4 1 AAA domain AAA_28 PF13521.6 RLN97272.1 - 1e-05 25.8 0.0 0.018 15.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 RLN97272.1 - 1.1e-05 25.3 0.2 0.089 12.7 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 RLN97272.1 - 1.5e-05 24.5 0.2 0.029 13.8 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 RLN97272.1 - 1.8e-05 24.6 0.1 0.017 14.8 0.0 2.7 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 RLN97272.1 - 2.1e-05 24.6 0.0 0.047 13.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 RLN97272.1 - 5.2e-05 23.8 0.0 0.0058 17.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RLN97272.1 - 5.9e-05 22.7 0.0 0.026 14.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region TsaE PF02367.17 RLN97272.1 - 0.00082 19.4 0.0 0.096 12.7 0.0 2.7 2 1 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 RLN97272.1 - 0.001 19.2 0.0 1.7 8.7 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain ATPase PF06745.13 RLN97272.1 - 0.0011 18.4 0.0 0.19 11.1 0.0 2.4 2 0 0 2 2 2 1 KaiC Zeta_toxin PF06414.12 RLN97272.1 - 0.0011 18.3 0.0 0.2 10.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_11 PF13086.6 RLN97272.1 - 0.0013 18.6 0.0 0.092 12.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 RLN97272.1 - 0.0013 18.4 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 RLN97272.1 - 0.0014 18.6 0.2 1.1 9.1 0.0 4.0 4 0 0 4 4 4 1 NACHT domain Sigma54_activat PF00158.26 RLN97272.1 - 0.0041 16.8 0.0 0.3 10.8 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain DUF815 PF05673.13 RLN97272.1 - 0.0048 16.1 0.0 0.089 11.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 RLN97272.1 - 0.011 16.2 0.0 0.71 10.4 0.0 2.7 2 1 0 2 2 2 0 ABC transporter AAA_17 PF13207.6 RLN97272.1 - 0.025 15.0 0.0 2.4 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 RLN97272.1 - 0.029 14.6 1.7 0.59 10.4 0.0 3.1 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Parvo_NS1 PF01057.17 RLN97272.1 - 0.046 12.8 0.0 0.23 10.5 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 SKI PF01202.22 RLN97272.1 - 0.06 13.5 0.0 3.5 7.7 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase PhoH PF02562.16 RLN97272.1 - 0.085 12.3 0.2 0.67 9.4 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 RLN97272.1 - 0.12 12.0 4.0 0.51 10.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 RLN97272.1 - 0.14 11.4 0.0 0.31 10.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin2 PF13189.6 RLN97272.1 - 0.16 12.1 0.0 15 5.6 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_19 PF13245.6 RLN97272.1 - 0.31 11.4 1.9 1.5 9.1 0.1 2.9 3 1 0 3 3 3 0 AAA domain Rota_NS53 PF00981.17 RLN97273.1 - 0.19 10.6 4.5 0.27 10.0 4.5 1.2 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) ABC2_membrane PF01061.24 RLN97275.1 - 3.2e-61 206.4 70.2 4.8e-33 114.3 28.4 2.5 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN97275.1 - 7.1e-16 59.0 0.0 1.4e-15 58.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter PDR_CDR PF06422.12 RLN97275.1 - 4.5e-06 26.5 0.0 4.5e-06 26.5 0.0 4.4 4 0 0 4 4 4 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 RLN97275.1 - 2.3e-05 23.7 42.7 0.0023 17.1 17.8 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 RLN97275.1 - 0.0001 22.3 0.1 0.084 12.7 0.0 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RLN97275.1 - 0.0034 17.3 0.0 0.0075 16.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase PDR_assoc PF08370.11 RLN97275.1 - 0.0055 16.4 12.5 0.08 12.7 0.0 3.7 3 0 0 3 3 2 2 Plant PDR ABC transporter associated AAA_29 PF13555.6 RLN97275.1 - 0.006 16.3 0.7 0.013 15.2 0.7 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN97275.1 - 0.059 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RLN97275.1 - 0.06 13.7 0.1 0.16 12.3 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 RLN97275.1 - 0.072 12.5 0.1 0.18 11.2 0.1 1.5 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Piezo_RRas_bdg PF12166.8 RLN97276.1 - 3.4e-89 300.1 0.3 3.4e-89 300.1 0.3 1.6 2 0 0 2 2 2 1 Piezo non-specific cation channel, R-Ras-binding domain fn3 PF00041.21 RLN97276.1 - 1.6e-11 44.4 0.0 5.5e-11 42.7 0.0 2.0 1 0 0 1 1 1 1 Fibronectin type III domain PH PF00169.29 RLN97276.1 - 3.5e-06 27.5 0.2 1.7e-05 25.3 0.2 2.3 1 0 0 1 1 1 1 PH domain Pur_ac_phosph_N PF16656.5 RLN97276.1 - 0.0022 18.5 0.0 0.011 16.3 0.0 2.2 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain BBP1_C PF15272.6 RLN97277.1 - 0.083 12.7 2.6 0.22 11.3 2.6 1.6 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal HAUS6_N PF14661.6 RLN97277.1 - 0.27 10.8 4.0 0.81 9.2 4.0 1.8 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus KHA PF11834.8 RLN97277.1 - 5.8 7.1 7.7 16 5.7 0.4 3.3 3 0 0 3 3 3 0 KHA, dimerisation domain of potassium ion channel Arm PF00514.23 RLN97278.1 - 2.7e-32 109.8 9.3 0.099 12.7 0.0 12.9 13 0 0 13 13 13 10 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 RLN97278.1 - 2e-13 50.2 0.4 0.0039 17.2 0.1 7.5 5 3 3 9 9 9 4 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 RLN97278.1 - 2e-11 44.1 19.8 0.0039 17.7 0.2 8.8 6 4 4 10 10 10 4 HEAT-like repeat HEAT_2 PF13646.6 RLN97278.1 - 5.4e-09 36.3 20.8 0.0022 18.4 0.6 6.4 2 1 3 7 7 7 5 HEAT repeats HEAT PF02985.22 RLN97278.1 - 4.8e-07 29.5 10.6 4 8.0 0.0 9.8 11 0 0 11 11 11 1 HEAT repeat Arm_2 PF04826.13 RLN97278.1 - 6.5e-07 29.1 0.0 5e-05 22.9 0.0 3.3 2 1 1 3 3 3 1 Armadillo-like HEAT_PBS PF03130.16 RLN97278.1 - 3.8e-05 24.0 28.9 5.7 7.9 0.1 10.5 11 0 0 11 11 10 1 PBS lyase HEAT-like repeat FERM_F1 PF18379.1 RLN97278.1 - 6.4e-05 22.9 0.1 1.3 9.1 0.0 4.8 1 1 4 5 5 5 1 FERM F1 ubiquitin-like domain RPAP1_C PF08620.10 RLN97278.1 - 0.012 15.7 0.0 33 4.7 0.0 4.8 5 0 0 5 5 5 0 RPAP1-like, C-terminal PSD2 PF07624.11 RLN97278.1 - 0.083 12.7 3.1 1.1e+02 2.7 0.0 5.6 7 0 0 7 7 7 0 Protein of unknown function (DUF1585) BmKX PF09132.10 RLN97278.1 - 1.5 8.9 3.4 78 3.4 0.0 3.9 3 0 0 3 3 3 0 BmKX Glyco_hydro_67C PF07477.12 RLN97278.1 - 1.7 8.2 4.1 84 2.6 0.0 4.3 5 0 0 5 5 5 0 Glycosyl hydrolase family 67 C-terminus MRP-L47 PF06984.13 RLN97279.1 - 3.6e-26 91.1 0.3 5.2e-26 90.6 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 RLN97279.1 - 9.8e-11 41.5 3.1 9.8e-11 41.5 3.1 1.7 2 0 0 2 2 2 1 Ribosomal L29 protein DUF3585 PF12130.8 RLN97279.1 - 1.1 9.4 6.7 4.1 7.5 6.7 1.8 1 1 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain ELFV_dehydrog PF00208.21 RLN97280.1 - 5.6e-55 186.7 0.0 1.6e-54 185.2 0.0 1.7 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 RLN97280.1 - 1.2e-18 66.1 0.1 8.4e-10 36.9 0.1 2.3 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 RLN97280.1 - 0.0081 16.0 0.0 0.033 14.1 0.0 2.0 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain UCH PF00443.29 RLN97281.1 - 5.1e-56 190.0 0.0 7.4e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN97281.1 - 2.9e-19 69.8 0.0 8.1e-19 68.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DNA_RNApol_7kD PF03604.13 RLN97281.1 - 5.8 6.7 7.3 11 5.8 1.6 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit HSP70 PF00012.20 RLN97282.1 - 4.7e-225 748.3 8.0 5.7e-225 748.1 8.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RLN97282.1 - 2.6e-13 49.5 0.0 5.1e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 RLN97282.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Abhydrolase_1 PF00561.20 RLN97283.1 - 2.6e-29 102.7 0.0 5.1e-29 101.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN97283.1 - 3e-22 80.3 3.5 4.8e-22 79.6 3.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN97283.1 - 9.2e-08 31.6 0.0 6.1e-07 28.9 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 RLN97283.1 - 8.1e-05 23.0 0.3 8.1e-05 23.0 0.3 1.8 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Ndr PF03096.14 RLN97283.1 - 0.26 10.0 0.0 0.42 9.3 0.0 1.3 1 0 0 1 1 1 0 Ndr family Abhydrolase_1 PF00561.20 RLN97284.1 - 1.8e-25 90.0 0.0 5.5e-25 88.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN97284.1 - 2.2e-21 77.5 1.3 3.2e-21 77.0 1.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN97284.1 - 1.4e-06 27.8 0.0 2.5e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 RLN97284.1 - 6.9e-05 23.2 0.1 6.9e-05 23.2 0.1 1.7 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 RLN97285.1 - 1.7e-17 63.9 0.0 4.1e-17 62.7 0.0 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN97285.1 - 5.6e-08 33.6 4.6 2e-07 31.9 4.7 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.12 RLN97285.1 - 1.6e-05 25.2 0.2 5.7e-05 23.4 0.1 2.0 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Hydrolase_4 PF12146.8 RLN97285.1 - 0.00079 18.8 0.8 0.014 14.6 0.3 2.8 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 RLN97285.1 - 0.0024 18.0 0.0 0.0041 17.2 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 RLN97286.1 - 2.3e-26 93.0 0.0 1.2e-25 90.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN97286.1 - 3.1e-20 73.7 0.5 4.1e-20 73.3 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN97286.1 - 1.6e-06 27.5 0.0 2.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 RLN97286.1 - 2.9e-05 24.4 0.1 5.5e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Mito_carr PF00153.27 RLN97287.1 - 1.2e-55 185.4 1.5 1.1e-17 63.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40_3 PF15911.5 RLN97288.1 - 3.3e-18 65.4 0.0 2e-17 62.9 0.0 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN97288.1 - 9.5e-11 41.9 0.0 0.0026 18.0 0.0 4.9 3 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 RLN97288.1 - 3.8e-06 26.8 0.4 4.2 7.2 0.0 5.0 4 1 1 5 5 5 2 Region in Clathrin and VPS IKI3 PF04762.12 RLN97288.1 - 0.0011 17.1 0.0 0.03 12.3 0.0 2.2 2 0 0 2 2 2 1 IKI3 family WD40 PF00400.32 RLN97288.1 - 0.0019 19.0 1.0 1.8 9.6 0.0 4.8 4 0 0 4 4 3 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 RLN97288.1 - 0.01 14.9 7.8 3.7 6.5 0.0 4.2 4 0 0 4 4 4 2 Coatomer WD associated region eIF2A PF08662.11 RLN97288.1 - 0.034 14.0 0.0 0.3 10.9 0.0 2.3 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 RLN97288.1 - 0.19 10.0 0.0 8.1 4.6 0.0 3.3 4 0 0 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz TPR_7 PF13176.6 RLN97288.1 - 0.23 11.6 17.4 33 4.8 0.3 7.8 7 0 0 7 7 7 0 Tetratricopeptide repeat Rad50_zn_hook PF04423.14 RLN97288.1 - 1.9 8.4 5.7 1.9 8.4 0.0 2.8 2 1 1 3 3 3 0 Rad50 zinc hook motif RIC1 PF07064.13 RLN97288.1 - 2.1 7.7 5.8 7.3 5.9 0.3 2.8 2 1 1 3 3 3 0 RIC1 DZR PF12773.7 RLN97288.1 - 2.7 8.1 12.3 62 3.7 12.3 2.6 1 1 0 1 1 1 0 Double zinc ribbon PNK3P PF08645.11 RLN97289.1 - 6.4e-53 178.8 0.0 8.4e-53 178.4 0.0 1.1 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase FYVE PF01363.21 RLN97290.1 - 1.9e-12 47.1 12.5 4.1e-12 46.1 12.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger TPR_1 PF00515.28 RLN97290.1 - 4.7e-10 38.9 1.2 0.002 17.9 0.0 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN97290.1 - 6.3e-10 38.6 0.1 0.0016 18.1 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 RLN97290.1 - 1.7e-09 37.2 1.4 0.0055 16.8 0.0 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN97290.1 - 1.1e-08 34.5 8.8 0.013 15.6 0.1 4.8 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN97290.1 - 2.9e-06 27.8 16.0 5e-05 23.9 0.6 4.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN97290.1 - 8.5e-06 26.2 7.6 5.9e-05 23.5 1.2 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN97290.1 - 9e-05 22.6 0.0 0.012 15.9 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN97290.1 - 0.00056 20.1 0.2 0.00056 20.1 0.2 5.1 3 1 3 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN97290.1 - 0.00071 19.4 0.5 0.00071 19.4 0.5 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN97290.1 - 0.0011 19.2 0.3 0.0039 17.4 0.3 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RLN97290.1 - 0.021 15.6 15.5 0.33 11.9 0.1 4.8 3 1 1 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 RLN97290.1 - 0.052 13.4 0.2 0.052 13.4 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3301 PF11743.8 RLN97290.1 - 0.086 12.5 0.1 0.27 11.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) Vps5 PF09325.10 RLN97290.1 - 0.11 12.0 10.3 0.025 14.1 3.7 2.9 3 0 0 3 3 3 0 Vps5 C terminal like TPR_4 PF07721.14 RLN97290.1 - 0.15 12.7 8.9 0.16 12.7 0.1 3.7 4 0 0 4 4 2 0 Tetratricopeptide repeat IFT57 PF10498.9 RLN97290.1 - 0.16 10.9 7.0 0.28 10.1 6.7 1.6 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 TPR_6 PF13174.6 RLN97290.1 - 0.28 11.9 1.9 38 5.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 RLN97290.1 - 0.67 9.9 4.0 0.92 9.4 2.4 2.1 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal Pkinase PF00069.25 RLN97291.1 - 8.3e-09 35.2 0.1 1.1e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain PH PF00169.29 RLN97291.1 - 1.7e-08 34.9 0.1 4.1e-08 33.7 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN97291.1 - 0.021 15.3 0.5 0.067 13.6 0.5 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain Pkinase_Tyr PF07714.17 RLN97291.1 - 0.055 12.7 0.1 0.081 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase PPR_2 PF13041.6 RLN97294.1 - 1.3e-17 63.7 0.1 0.78 10.0 0.0 11.6 11 1 1 12 12 12 3 PPR repeat family PPR PF01535.20 RLN97294.1 - 3.3e-12 45.8 7.8 0.2 12.0 0.0 11.7 16 1 0 16 16 13 2 PPR repeat PPR_long PF17177.4 RLN97294.1 - 3.5e-08 33.1 5.2 0.048 13.0 2.9 6.3 3 1 2 6 6 6 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 RLN97294.1 - 1.9e-05 24.6 0.0 21 5.3 0.0 6.7 6 2 2 8 8 8 0 Pentatricopeptide repeat domain PPR_1 PF12854.7 RLN97294.1 - 0.0018 17.9 0.5 50 3.7 0.0 6.2 8 0 0 8 8 8 0 PPR repeat TPR_7 PF13176.6 RLN97294.1 - 0.011 15.7 10.7 1.2 9.4 0.0 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN97294.1 - 0.053 14.2 6.4 0.47 11.2 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4081 PF13312.6 RLN97294.1 - 0.053 13.7 0.1 3.6 7.8 0.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4081) TPR_19 PF14559.6 RLN97294.1 - 0.1 13.1 32.8 0.35 11.4 1.6 8.6 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_4 PF07721.14 RLN97294.1 - 0.79 10.5 7.9 81 4.3 0.2 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN97294.1 - 0.94 10.5 22.8 20 6.4 0.1 10.0 10 1 1 11 11 10 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN97294.1 - 3.9 8.2 17.8 2.5 8.8 0.2 6.4 6 1 0 6 6 5 0 Tetratricopeptide repeat 2-Hacid_dh_C PF02826.19 RLN97295.1 - 4.4e-08 32.7 0.1 5.4e-08 32.4 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DEAD PF00270.29 RLN97296.1 - 3.8e-06 26.8 0.4 0.014 15.2 0.1 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN97296.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.8 1 1 0 1 1 1 0 Helicase conserved C-terminal domain CBS PF00571.28 RLN97296.1 - 0.057 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 CBS domain mRNA_triPase PF02940.15 RLN97297.1 - 9.9e-18 64.7 0.0 7.2e-17 61.8 0.0 1.9 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain mRNA_cap_enzyme PF01331.19 RLN97297.1 - 8.7e-11 42.0 0.0 1.3e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.21 RLN97297.1 - 0.075 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 ATP dependent DNA ligase domain Gas_vesicle PF00741.18 RLN97297.1 - 0.13 12.4 0.2 0.38 10.9 0.2 1.7 1 0 0 1 1 1 0 Gas vesicle protein DUF667 PF05018.13 RLN97298.1 - 1.4e-57 194.4 0.0 2.2e-57 193.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Ank_4 PF13637.6 RLN97298.1 - 5.4e-49 164.0 30.4 2.1e-06 28.2 0.2 12.3 8 4 7 15 15 15 12 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN97298.1 - 2.5e-42 143.3 17.8 7.9e-08 32.8 0.2 7.8 1 1 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN97298.1 - 1.7e-38 130.1 37.3 2.6e-05 24.4 0.5 16.9 4 2 14 18 18 18 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN97298.1 - 2.6e-17 61.1 25.4 0.46 11.2 0.0 15.3 8 6 8 16 16 16 4 Ankyrin repeat Ank PF00023.30 RLN97298.1 - 6.1e-09 35.9 8.9 1.3 9.6 0.0 9.7 4 3 3 7 7 7 2 Ankyrin repeat UDPGP PF01704.18 RLN97299.1 - 4.8e-123 410.8 0.0 6.3e-123 410.5 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PGM_PMM_I PF02878.16 RLN97299.1 - 1.6e-29 102.4 0.0 1e-28 99.8 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 RLN97299.1 - 9.5e-26 90.2 0.0 2.2e-25 89.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 RLN97299.1 - 5.2e-07 30.2 0.1 3.1e-06 27.7 0.0 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 RLN97299.1 - 6.8e-05 23.0 0.0 0.00024 21.2 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Sugar_tr PF00083.24 RLN97300.1 - 1.2e-101 340.8 23.6 1.4e-101 340.6 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN97300.1 - 2.8e-21 75.8 43.7 8.1e-16 57.9 10.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Helicase_C_3 PF13625.6 RLN97301.1 - 4.6e-35 120.5 0.0 7.6e-35 119.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN97301.1 - 7.2e-05 22.8 0.4 0.00047 20.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Ank_2 PF12796.7 RLN97302.1 - 3.8e-14 53.0 3.3 2.3e-08 34.5 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Isochorismatase PF00857.20 RLN97302.1 - 4.8e-14 52.9 0.0 2.3e-13 50.7 0.0 2.1 1 1 0 1 1 1 1 Isochorismatase family Ank_5 PF13857.6 RLN97302.1 - 2e-10 40.7 1.6 2.1e-07 31.1 0.5 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN97302.1 - 9e-10 38.9 2.4 2.1e-06 28.1 0.8 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) WW PF00397.26 RLN97302.1 - 6.1e-08 32.6 1.9 6.1e-08 32.6 1.9 1.8 2 0 0 2 2 2 1 WW domain PA PF02225.22 RLN97302.1 - 3e-07 30.3 0.2 7.8e-07 29.0 0.2 1.7 1 0 0 1 1 1 1 PA domain Ank PF00023.30 RLN97302.1 - 1.1e-05 25.6 2.0 0.01 16.3 0.3 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 RLN97302.1 - 3.2e-05 24.0 1.7 0.16 12.6 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat FTZ PF03867.14 RLN97302.1 - 0.25 10.8 3.4 0.14 11.7 0.2 2.0 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region Transposase_1 PF01359.18 RLN97303.1 - 0.0037 17.1 0.0 0.0068 16.2 0.0 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) EF-hand_7 PF13499.6 RLN97304.1 - 5.6e-14 52.4 0.6 7.3e-10 39.2 0.1 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN97304.1 - 4.8e-11 41.7 0.2 0.016 15.1 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 RLN97304.1 - 7e-10 37.7 0.0 0.0055 16.2 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 RLN97304.1 - 4.5e-09 36.0 0.0 3.2e-06 26.9 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN97304.1 - 0.00056 19.3 0.0 3.9 7.1 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 RLN97304.1 - 0.0028 17.9 0.0 0.041 14.2 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_11 PF08976.11 RLN97304.1 - 0.012 16.5 0.0 0.035 15.0 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain SPARC_Ca_bdg PF10591.9 RLN97304.1 - 0.18 12.1 0.0 29 5.0 0.0 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF908 PF06012.12 RLN97305.1 - 4.5 6.6 4.3 5.8 6.2 4.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) TALPID3 PF15324.6 RLN97305.1 - 6.4 4.3 8.1 8.5 3.9 8.1 1.1 1 0 0 1 1 1 0 Hedgehog signalling target G-patch_2 PF12656.7 RLN97307.1 - 1.5e-15 57.0 0.4 5e-15 55.3 0.0 2.1 2 0 0 2 2 2 1 G-patch domain SET PF00856.28 RLN97309.1 - 8e-18 65.4 0.0 3.5e-17 63.3 0.0 2.0 1 1 0 1 1 1 1 SET domain SBF PF01758.16 RLN97310.1 - 9e-13 48.3 0.9 9e-13 48.3 0.9 2.2 1 1 1 2 2 2 1 Sodium Bile acid symporter family DUF1600 PF07667.11 RLN97310.1 - 0.053 13.7 5.9 0.18 12.0 5.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1600) Herpes_LMP1 PF05297.11 RLN97310.1 - 0.33 10.1 3.4 0.48 9.6 3.4 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2208 PF09973.9 RLN97310.1 - 1.6 8.3 8.6 0.23 11.0 4.5 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) ABC2_membrane_2 PF12679.7 RLN97310.1 - 7 5.8 17.1 9.1 5.5 17.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein RPEL PF02755.15 RLN97311.1 - 9.9e-15 53.7 15.5 0.00014 21.5 0.1 5.2 5 0 0 5 5 5 4 RPEL repeat DUF1543 PF07566.12 RLN97311.1 - 0.1 12.4 0.4 3.2 7.6 0.0 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1543) AAA PF00004.29 RLN97312.1 - 1.1e-52 177.9 0.1 1.9e-40 138.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Peptidase_M3 PF01432.20 RLN97312.1 - 9.2e-24 84.5 0.1 1.5e-23 83.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M3 AAA_16 PF13191.6 RLN97312.1 - 2.7e-10 40.9 0.2 0.0014 19.0 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_lid_3 PF17862.1 RLN97312.1 - 6.7e-10 38.6 0.1 2.6e-09 36.7 0.1 2.0 1 1 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 RLN97312.1 - 4.2e-08 32.8 0.0 0.0017 17.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 RLN97312.1 - 1e-07 32.0 0.0 0.00065 19.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RLN97312.1 - 3.7e-07 30.4 0.1 2.1e-05 24.7 0.0 2.8 2 1 1 3 3 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 RLN97312.1 - 2e-06 27.6 0.1 0.051 13.3 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RLN97312.1 - 2.4e-06 27.8 4.5 0.013 15.8 0.5 4.3 2 2 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 RLN97312.1 - 1.8e-05 24.5 0.0 0.059 13.1 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain RNA_helicase PF00910.22 RLN97312.1 - 4.4e-05 23.8 0.0 0.051 14.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 RLN97312.1 - 5.7e-05 23.2 0.0 0.11 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 RLN97312.1 - 6.5e-05 22.9 0.0 0.49 10.4 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 RLN97312.1 - 8.1e-05 22.6 0.2 0.09 12.7 0.1 3.1 2 1 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 RLN97312.1 - 0.00016 21.1 0.1 0.0044 16.4 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 RLN97312.1 - 0.00019 20.9 0.2 2.4 7.5 0.0 3.4 2 1 0 3 3 3 1 Bacterial TniB protein ABC_tran PF00005.27 RLN97312.1 - 0.0002 21.9 0.3 0.0089 16.5 0.0 2.6 2 0 0 2 2 2 1 ABC transporter IstB_IS21 PF01695.17 RLN97312.1 - 0.00023 21.0 0.0 0.17 11.6 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 RLN97312.1 - 0.00031 20.9 0.0 0.03 14.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 RLN97312.1 - 0.00038 19.7 0.0 0.58 9.3 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain ATPase_2 PF01637.18 RLN97312.1 - 0.00055 19.9 0.4 2.1 8.2 0.0 3.5 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 RLN97312.1 - 0.0006 19.4 0.0 0.077 12.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase PF06745.13 RLN97312.1 - 0.0011 18.4 0.0 0.023 14.1 0.0 2.4 2 0 0 2 2 2 1 KaiC AAA_24 PF13479.6 RLN97312.1 - 0.0019 17.9 0.1 0.48 10.1 0.0 2.9 2 2 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RLN97312.1 - 0.002 17.5 0.0 2.6 7.3 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_23 PF13476.6 RLN97312.1 - 0.0064 17.0 0.0 0.3 11.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 RLN97312.1 - 0.0081 16.2 0.0 1 9.3 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Bac_DnaA PF00308.18 RLN97312.1 - 0.012 15.5 0.0 0.55 10.0 0.0 2.5 3 0 0 3 3 2 0 Bacterial dnaA protein DUF815 PF05673.13 RLN97312.1 - 0.02 14.0 0.1 0.71 9.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 RLN97312.1 - 0.021 14.9 0.0 16 5.6 0.0 3.3 4 0 0 4 4 2 0 Sigma-54 interaction domain Rad17 PF03215.15 RLN97312.1 - 0.022 14.7 0.0 0.081 12.8 0.0 1.9 2 0 0 2 2 1 0 Rad17 P-loop domain AAA_25 PF13481.6 RLN97312.1 - 0.022 14.4 2.5 2.7 7.5 0.0 3.0 2 1 1 3 3 3 0 AAA domain PhoH PF02562.16 RLN97312.1 - 0.03 13.8 0.1 7.8 5.9 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 RLN97312.1 - 0.039 13.7 0.0 0.74 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RLN97312.1 - 0.041 14.4 0.0 0.3 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.10 RLN97312.1 - 0.06 13.4 0.0 6.7 6.8 0.0 2.6 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain DAP3 PF10236.9 RLN97312.1 - 0.13 11.4 0.1 5.4 6.1 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_3 PF07726.11 RLN97312.1 - 0.14 12.0 0.0 1.7 8.5 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 RLN97312.1 - 0.2 12.0 0.4 1.9 8.9 0.0 2.6 2 1 1 3 3 2 0 AAA domain FGGY_N PF00370.21 RLN97314.1 - 3.2e-21 76.0 0.2 1.4e-12 47.7 0.0 2.4 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain HTH_23 PF13384.6 RLN97314.1 - 0.00017 21.3 0.1 0.0013 18.5 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 RLN97314.1 - 0.0022 18.1 0.1 0.0085 16.2 0.1 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 RLN97314.1 - 0.0082 16.4 0.1 0.024 14.9 0.1 1.7 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 RLN97314.1 - 0.14 12.2 0.2 0.34 11.0 0.2 1.7 1 0 0 1 1 1 0 Winged helix-turn helix MerR PF00376.23 RLN97314.1 - 0.15 11.8 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 MerR family regulatory protein Cyclin_N PF00134.23 RLN97315.1 - 9.7e-13 48.0 0.1 1.9e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 RLN97315.1 - 0.0016 18.4 0.1 0.0035 17.3 0.1 1.6 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Imm3 PF14425.6 RLN97315.1 - 0.05 13.6 0.4 0.084 12.9 0.4 1.4 1 0 0 1 1 1 0 Immunity protein Imm3 Actin PF00022.19 RLN97316.1 - 1.2e-67 228.3 0.0 1.4e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Actin Sec10 PF07393.11 RLN97318.1 - 1.8e-45 155.7 6.7 2.2e-45 155.3 6.7 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 EzrA PF06160.12 RLN97318.1 - 0.46 8.6 5.5 1.2 7.2 5.5 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Med21 PF11221.8 RLN97318.1 - 4 7.7 8.3 24 5.2 0.2 3.6 3 0 0 3 3 3 0 Subunit 21 of Mediator complex Cyclin_N PF00134.23 RLN97319.1 - 8.6e-23 80.5 1.2 8.6e-23 80.5 1.2 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 RLN97319.1 - 2.6e-07 30.8 0.5 5.3e-07 29.7 0.1 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain VWA_2 PF13519.6 RLN97320.1 - 4.6e-05 24.0 0.3 0.00011 22.8 0.3 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 RLN97320.1 - 5.9e-05 23.4 0.5 9.7e-05 22.7 0.5 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain APC1_C PF18122.1 RLN97320.1 - 0.038 13.9 0.7 0.2 11.6 0.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain DnaJ PF00226.31 RLN97322.1 - 6.7e-13 48.6 0.1 1.1e-11 44.6 0.1 2.7 1 1 0 1 1 1 1 DnaJ domain MPDZ_u10 PF16667.5 RLN97322.1 - 0.0056 17.6 1.3 0.029 15.2 1.3 2.3 1 0 0 1 1 1 1 Unstructured region 10 on multiple PDZ protein RRM_1 PF00076.22 RLN97323.1 - 3e-17 62.2 1.7 6.6e-05 22.7 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RLN97323.1 - 0.0085 15.9 0.7 4 7.4 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 RLN97323.1 - 0.068 12.8 0.1 28 4.3 0.0 3.3 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GDPD PF03009.17 RLN97324.1 - 1.2e-52 179.3 0.0 2.4e-52 178.2 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family cNMP_binding PF00027.29 RLN97324.1 - 4.3e-12 45.9 0.0 1.5e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain CBM_20 PF00686.19 RLN97324.1 - 4.7e-12 45.7 0.0 1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain F5_F8_type_C PF00754.25 RLN97324.1 - 2.1e-05 24.6 0.1 0.0029 17.7 0.1 3.1 2 0 0 2 2 2 1 F5/8 type C domain NYD-SP28 PF14772.6 RLN97325.1 - 3.7e-28 97.5 12.1 3.7e-28 97.5 12.1 6.4 3 1 3 7 7 7 1 Sperm tail NYD-SP28_assoc PF14775.6 RLN97325.1 - 3e-18 65.7 0.2 3e-18 65.7 0.2 5.0 5 1 1 6 6 6 1 Sperm tail C-terminal domain CutA1 PF03091.15 RLN97325.1 - 0.1 12.5 0.9 0.46 10.4 0.9 2.1 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein Flavodoxin_2 PF02525.17 RLN97325.1 - 4.2 7.0 10.9 0.15 11.7 1.6 3.1 2 1 1 3 3 3 0 Flavodoxin-like fold Serinc PF03348.15 RLN97326.1 - 3.1e-26 92.3 0.1 3.5e-26 92.1 0.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF5134 PF17197.4 RLN97326.1 - 0.023 14.6 0.5 0.1 12.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) CCSMST1 PF15013.6 RLN97326.1 - 0.053 13.7 0.0 0.56 10.4 0.0 2.2 2 0 0 2 2 2 0 CCSMST1 family WD40 PF00400.32 RLN97327.1 - 1.8e-09 38.0 0.2 0.00063 20.5 0.0 4.1 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.8 RLN97327.1 - 0.0013 17.4 0.0 0.0021 16.8 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 RLN97327.1 - 0.033 14.5 0.0 7.9 6.9 0.0 2.7 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 RLN97327.1 - 0.066 11.9 0.0 6.9 5.3 0.0 2.1 1 1 1 2 2 2 0 Nup133 N terminal like RET_CLD3 PF17812.1 RLN97328.1 - 0.014 15.6 0.1 0.021 15.1 0.1 1.2 1 0 0 1 1 1 0 RET Cadherin like domain 3 ARL2_Bind_BART PF11527.8 RLN97329.1 - 3e-19 69.2 0.7 1e-16 61.1 0.7 2.2 1 1 0 1 1 1 1 The ARF-like 2 binding protein BART CH PF00307.31 RLN97330.1 - 0.011 16.0 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Calponin homology (CH) domain Aminotran_5 PF00266.19 RLN97332.1 - 6e-58 196.6 1.0 5.5e-57 193.4 0.3 2.2 2 1 0 2 2 2 2 Aminotransferase class-V Mito_carr PF00153.27 RLN97333.1 - 8e-45 150.7 0.6 1.4e-18 66.6 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein WW PF00397.26 RLN97334.1 - 3.9e-07 30.0 1.2 8.9e-07 28.9 1.2 1.6 1 0 0 1 1 1 1 WW domain APG6 PF04111.12 RLN97335.1 - 1.6e-60 204.1 0.0 2.8e-60 203.3 0.0 1.4 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 RLN97335.1 - 6e-14 52.7 1.1 6e-14 52.7 1.1 2.6 3 0 0 3 3 3 1 Apg6 coiled-coil region DUF1690 PF07956.11 RLN97336.1 - 0.19 12.1 1.7 5.4 7.4 1.2 2.9 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Spem1 PF15670.5 RLN97336.1 - 4.3 6.8 12.8 4.1 6.9 0.1 3.7 4 1 0 4 4 4 0 Spermatid maturation protein 1 DUF724 PF05266.14 RLN97336.1 - 5.4 6.8 9.0 7.5 6.3 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF724) CCDC53 PF10152.9 RLN97337.1 - 0.21 12.0 3.2 1 9.8 3.2 2.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex CENP-Q PF13094.6 RLN97337.1 - 0.6 10.3 14.4 0.044 14.0 1.1 3.2 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit FlxA PF14282.6 RLN97337.1 - 3.9 7.5 7.2 0.33 11.0 1.9 1.9 2 0 0 2 2 2 0 FlxA-like protein GSH_synth_ATP PF03917.17 RLN97338.1 - 1.4e-114 382.7 0.0 1.8e-114 382.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 RLN97338.1 - 1.7e-35 121.6 0.0 3.6e-35 120.5 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DHHC PF01529.20 RLN97339.1 - 1.4e-24 86.7 7.0 1.4e-24 86.7 7.0 3.0 3 0 0 3 3 3 1 DHHC palmitoyltransferase GBR2_CC PF18455.1 RLN97339.1 - 0.044 13.9 0.7 0.044 13.9 0.7 1.9 2 0 0 2 2 2 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain Helitron_like_N PF14214.6 RLN97341.1 - 1.8e-11 44.6 0.0 5.2e-11 43.1 0.0 1.7 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus LTV PF04180.14 RLN97342.1 - 1.8e-17 64.1 45.1 3.6e-14 53.3 22.1 3.9 1 1 2 3 3 3 2 Low temperature viability protein LMBR1 PF04791.16 RLN97342.1 - 3.1 6.6 5.4 4.1 6.2 5.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PorA PF11271.8 RLN97342.1 - 3.9 6.7 10.0 0.58 9.4 6.0 1.6 2 0 0 2 2 2 0 Porin PorA HSF_DNA-bind PF00447.17 RLN97343.1 - 4.1e-24 85.0 0.1 6.4e-24 84.4 0.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Hist_deacetyl PF00850.19 RLN97344.1 - 1.4e-61 208.7 0.0 2.8e-61 207.7 0.0 1.4 2 0 0 2 2 2 1 Histone deacetylase domain Ank_2 PF12796.7 RLN97344.1 - 4.1e-08 33.7 0.6 0.18 12.4 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN97344.1 - 9.5e-06 26.1 0.5 0.38 11.4 0.1 3.9 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN97344.1 - 0.00015 22.0 0.6 0.3 11.4 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN97344.1 - 0.00033 20.9 4.6 50 5.0 0.1 6.1 5 0 0 5 5 5 0 Ankyrin repeat B12-binding PF02310.19 RLN97344.1 - 0.07 13.2 0.0 11 6.1 0.0 2.5 2 0 0 2 2 2 0 B12 binding domain Ank PF00023.30 RLN97344.1 - 6.3 7.4 6.4 76 4.0 0.1 4.3 5 1 0 5 5 5 0 Ankyrin repeat DEAD PF00270.29 RLN97345.1 - 3.8e-06 26.8 0.4 0.014 15.2 0.1 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN97345.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.8 1 1 0 1 1 1 0 Helicase conserved C-terminal domain CBS PF00571.28 RLN97345.1 - 0.057 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 CBS domain ABC_membrane PF00664.23 RLN97347.1 - 1e-19 71.2 1.1 4.9e-11 42.8 0.0 3.4 3 1 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 RLN97347.1 - 8.7e-18 65.2 0.0 2.8e-13 50.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN97347.1 - 0.057 13.2 0.0 0.9 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 RLN97347.1 - 0.061 13.4 0.0 0.36 10.9 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Kinesin PF00225.23 RLN97348.1 - 4.1e-96 321.8 0.0 1.2e-95 320.3 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RLN97348.1 - 5.4e-41 140.0 0.0 2e-40 138.2 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding YabA PF06156.13 RLN97348.1 - 0.032 14.9 15.1 8.1 7.2 0.0 4.7 3 1 1 4 4 4 0 Initiation control protein YabA IFP_35_N PF07334.13 RLN97348.1 - 0.092 12.8 0.2 0.46 10.6 0.2 2.2 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Bac_DnaA PF00308.18 RLN97348.1 - 0.19 11.5 3.6 0.32 10.8 0.0 2.7 3 0 0 3 3 3 0 Bacterial dnaA protein Spc7 PF08317.11 RLN97348.1 - 0.27 10.1 21.3 0.35 9.7 11.6 2.7 2 1 1 3 3 3 0 Spc7 kinetochore protein IFT57 PF10498.9 RLN97348.1 - 0.34 9.8 11.5 0.19 10.6 7.1 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 AAA_22 PF13401.6 RLN97348.1 - 0.35 11.1 2.6 0.73 10.1 0.0 2.8 2 1 1 3 3 3 0 AAA domain DUF4407 PF14362.6 RLN97348.1 - 1.8 7.8 10.9 5.2 6.3 10.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 RLN97348.1 - 4.8 4.6 19.3 6.7 4.1 19.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4404 PF14357.6 RLN97348.1 - 4.8 7.9 11.9 13 6.5 2.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) THOC7 PF05615.13 RLN97348.1 - 5.7 7.2 15.8 8.5 6.7 5.2 2.7 1 1 1 2 2 2 0 Tho complex subunit 7 WD40 PF00400.32 RLN97349.1 - 0.00017 22.3 1.5 0.00058 20.6 0.7 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN97349.1 - 0.012 15.9 0.1 0.017 15.4 0.1 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Tox-HDC PF15656.6 RLN97349.1 - 0.04 14.1 0.0 0.042 14.0 0.0 1.0 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature Ras PF00071.22 RLN97350.1 - 4.4e-36 123.9 0.0 6e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN97350.1 - 3.4e-26 91.8 0.0 5.4e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Smg4_UPF3 PF03467.15 RLN97350.1 - 8.8e-26 91.0 0.0 2.2e-25 89.6 0.0 1.7 1 0 0 1 1 1 1 Smg-4/UPF3 family Arf PF00025.21 RLN97350.1 - 1.6e-08 34.2 0.0 2.6e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RLN97350.1 - 0.0017 17.8 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RLN97350.1 - 0.015 15.3 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase CEP63 PF17045.5 RLN97351.1 - 0.00034 20.6 10.4 0.00034 20.6 10.4 3.1 1 1 2 3 3 3 2 Centrosomal protein of 63 kDa FAM76 PF16046.5 RLN97351.1 - 0.12 11.7 40.0 0.87 8.9 28.0 2.3 2 0 0 2 2 2 0 FAM76 protein Fez1 PF06818.15 RLN97351.1 - 0.71 10.3 54.6 0.48 10.8 20.3 2.4 1 1 0 2 2 2 0 Fez1 DUF5631 PF18645.1 RLN97351.1 - 4.8 7.6 6.5 7.5 7.0 0.4 2.9 2 2 0 2 2 2 0 Family of unknown function (DUF5631) Gly_transf_sug PF04488.15 RLN97353.1 - 7.6e-11 42.5 0.0 1.4e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 RLN97353.1 - 1.8e-05 24.3 0.0 2.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gb3_synth PF04572.12 RLN97353.1 - 0.047 13.9 0.0 0.087 13.0 0.0 1.5 1 0 0 1 1 1 0 Alpha 1,4-glycosyltransferase conserved region STAT_alpha PF01017.20 RLN97354.1 - 0.015 15.2 6.2 0.015 15.2 6.2 2.1 1 1 1 2 2 2 0 STAT protein, all-alpha domain Cep57_CLD_2 PF14197.6 RLN97354.1 - 0.019 15.1 10.7 0.019 15.1 10.7 2.7 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Flexi_CP_N PF08358.10 RLN97354.1 - 0.05 13.6 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 Carlavirus coat DUF1515 PF07439.11 RLN97354.1 - 0.15 12.1 6.1 0.6 10.2 5.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) UPF0242 PF06785.11 RLN97354.1 - 0.39 10.8 25.2 0.2 11.7 10.3 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 RLN97354.1 - 0.62 10.1 18.6 0.47 10.5 15.6 2.2 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.21 RLN97354.1 - 0.7 10.0 19.6 0.056 13.5 3.8 3.7 2 1 2 4 4 4 0 bZIP transcription factor HIP1_clath_bdg PF16515.5 RLN97354.1 - 2 9.1 22.4 1.2 9.8 6.3 2.7 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Sec2p PF06428.11 RLN97354.1 - 2.6 8.1 23.6 1.1 9.3 3.3 3.5 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p DUF883 PF05957.13 RLN97354.1 - 4.6 7.9 10.1 0.68 10.6 0.4 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF3106 PF11304.8 RLN97354.1 - 5.1 7.6 15.1 8 7.0 5.6 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3106) HalX PF08663.10 RLN97354.1 - 5.7 7.3 14.5 5.2 7.5 2.9 3.6 1 1 2 3 3 3 0 HalX domain FAM76 PF16046.5 RLN97354.1 - 6.4 6.0 19.6 16 4.7 19.6 1.6 1 1 0 1 1 1 0 FAM76 protein PQ-loop PF04193.14 RLN97355.1 - 0.012 15.4 0.6 0.022 14.5 0.1 1.8 2 1 0 2 2 2 0 PQ loop repeat CLPTM1 PF05602.12 RLN97355.1 - 1.1 8.2 4.2 1.5 7.8 4.2 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Endonuclease_5 PF04493.14 RLN97357.1 - 8.3e-56 188.8 0.0 1.1e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V TPR_2 PF07719.17 RLN97358.1 - 7.3e-41 135.0 0.6 0.0003 20.7 0.0 9.9 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_1 PF00515.28 RLN97358.1 - 4.1e-35 118.2 0.2 0.00011 21.8 0.0 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 RLN97358.1 - 3.5e-32 107.9 0.3 0.0016 18.5 0.0 8.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.6 RLN97358.1 - 2.5e-29 100.7 0.3 1.3e-08 34.3 0.0 7.7 4 2 3 7 7 7 6 TPR repeat TPR_12 PF13424.6 RLN97358.1 - 1.2e-21 76.8 8.2 0.00011 22.4 0.2 7.0 5 2 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 RLN97358.1 - 4.8e-19 67.4 0.8 0.0013 19.3 0.0 8.8 3 2 7 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 RLN97358.1 - 6.3e-19 68.4 0.0 0.00078 20.0 0.0 5.7 3 2 2 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 RLN97358.1 - 6.5e-18 63.8 7.0 0.0018 18.5 0.0 8.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 RLN97358.1 - 1.6e-16 59.0 0.5 0.069 13.2 0.0 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN97358.1 - 1.2e-15 57.4 6.6 0.012 15.9 0.1 6.5 3 3 4 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 RLN97358.1 - 1.6e-15 57.3 0.4 0.17 12.4 0.0 7.0 4 3 2 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 RLN97358.1 - 2.1e-13 50.2 0.1 0.0081 16.3 0.0 5.7 2 1 5 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 RLN97358.1 - 6.4e-11 42.2 1.0 0.21 12.3 0.0 8.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN97358.1 - 5.8e-08 32.4 8.0 7.5 6.6 0.0 7.6 8 0 0 8 8 7 0 Tetratricopeptide repeat NARP1 PF12569.8 RLN97358.1 - 1.5e-06 27.5 0.7 0.0016 17.5 0.2 3.2 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 RLN97358.1 - 9.9e-06 25.0 0.1 0.54 9.4 0.1 4.5 1 1 4 6 6 6 3 Tetratricopeptide repeat TPR_3 PF07720.12 RLN97358.1 - 0.00052 19.9 3.2 16 5.6 0.1 5.4 6 1 2 8 8 6 0 Tetratricopeptide repeat TPR_MalT PF17874.1 RLN97358.1 - 0.0013 18.2 0.1 0.24 10.7 0.0 3.0 2 1 1 3 3 3 1 MalT-like TPR region PknG_TPR PF16918.5 RLN97358.1 - 0.0017 17.2 0.1 0.24 10.1 0.0 2.2 2 0 0 2 2 2 1 Protein kinase G tetratricopeptide repeat BTAD PF03704.17 RLN97358.1 - 0.0053 17.2 0.8 0.032 14.7 0.1 2.6 3 0 0 3 3 3 1 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 RLN97358.1 - 0.013 15.5 1.5 30 4.8 0.0 5.1 5 1 1 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat Wzy_C_2 PF11846.8 RLN97358.1 - 0.022 14.7 0.2 0.64 9.9 0.0 3.2 4 0 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal DUF3808 PF10300.9 RLN97358.1 - 0.13 11.0 3.5 0.5 9.0 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3808) OMS28_porin PF03532.13 RLN97358.1 - 0.36 10.0 0.9 0.66 9.2 0.1 1.7 2 0 0 2 2 2 0 OMS28 porin Erf4 PF10256.9 RLN97359.1 - 2.8e-05 24.2 0.0 4.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family HAMP PF00672.25 RLN97361.1 - 0.48 10.9 4.7 2.5 8.6 0.0 3.6 4 0 0 4 4 4 0 HAMP domain Na_Pi_cotrans PF02690.15 RLN97362.1 - 2.7e-34 118.2 31.3 4.8e-20 72.1 8.7 3.2 2 1 1 3 3 3 2 Na+/Pi-cotransporter DHHC PF01529.20 RLN97362.1 - 3.7 7.7 0.0 3.7 7.7 0.0 3.6 4 0 0 4 4 4 0 DHHC palmitoyltransferase Palm_thioest PF02089.15 RLN97363.1 - 6e-42 144.2 0.0 7e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 RLN97363.1 - 0.00058 19.6 0.6 0.0017 18.0 0.4 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 RLN97363.1 - 0.0068 16.0 0.2 0.014 15.0 0.1 1.5 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase DUF676 PF05057.14 RLN97363.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 RLN97363.1 - 0.12 11.6 1.2 0.27 10.5 0.5 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 GST_C_2 PF13410.6 RLN97364.1 - 0.0025 17.8 0.0 0.018 15.0 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RLN97364.1 - 0.029 14.6 0.0 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Metallopep PF12044.8 RLN97365.1 - 3.8e-62 210.3 0.0 5.2e-62 209.8 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 RLN97365.1 - 8.1e-11 42.0 0.0 0.00012 22.0 0.0 3.3 3 0 0 3 3 3 2 Jacalin-like lectin domain Reprolysin_3 PF13582.6 RLN97365.1 - 0.024 15.2 0.4 0.045 14.3 0.4 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 RLN97365.1 - 0.048 13.8 0.5 0.21 11.7 0.1 2.0 2 0 0 2 2 2 0 Metallo-peptidase family M12 Peptidase_M54 PF07998.11 RLN97365.1 - 0.064 13.2 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin_4 PF13583.6 RLN97365.1 - 0.089 12.4 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 RLN97365.1 - 0.1 11.5 0.7 0.18 10.7 0.7 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.24 RLN97365.1 - 0.14 12.0 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 Matrixin Nup84_Nup100 PF04121.13 RLN97366.1 - 7.8e-151 503.7 10.8 9.7e-151 503.3 10.8 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 HMMR_C PF15908.5 RLN97366.1 - 0.0018 18.6 1.5 0.0061 16.8 0.3 2.3 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor C-terminal ubiquitin PF00240.23 RLN97366.1 - 0.063 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family SSP160 PF06933.11 RLN97368.1 - 1.2 7.2 3.1 1.8 6.7 3.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Enkurin PF13864.6 RLN97368.1 - 2.2 8.7 7.4 1.1 9.8 2.8 2.5 2 1 0 2 2 2 0 Calmodulin-binding SDF PF00375.18 RLN97369.1 - 1.6e-65 221.7 20.1 1.7e-65 221.5 20.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family VMA21 PF09446.10 RLN97369.1 - 2.1 8.5 10.9 0.59 10.3 6.3 2.4 3 0 0 3 3 3 0 VMA21-like domain Ank_4 PF13637.6 RLN97371.1 - 3.3e-06 27.5 0.1 0.048 14.3 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN97371.1 - 0.00012 22.3 0.6 0.17 12.2 0.1 3.5 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN97371.1 - 0.00021 21.8 0.0 0.00095 19.7 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN97371.1 - 0.0056 17.1 0.6 15 6.6 0.0 4.0 3 1 1 4 4 4 1 Ankyrin repeat Sugar_tr PF00083.24 RLN97372.1 - 2.1e-40 139.0 4.5 2.7e-40 138.6 4.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN97372.1 - 1.4e-16 60.4 19.5 3.3e-16 59.2 19.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 RLN97372.1 - 3.6e-07 29.0 4.6 4.8e-07 28.6 4.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 RLN97372.1 - 1.1e-05 25.0 10.1 1.6e-05 24.4 10.1 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_5 PF05631.14 RLN97372.1 - 0.00024 20.2 1.9 0.00034 19.7 1.9 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM SPW PF03779.14 RLN97372.1 - 0.0073 15.9 4.2 0.44 10.2 0.4 3.2 2 0 0 2 2 2 2 SPW repeat MscL PF01741.18 RLN97372.1 - 0.095 13.0 0.2 0.16 12.3 0.2 1.3 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL Lung_7-TM_R PF06814.13 RLN97373.1 - 2.9e-38 131.8 12.3 2.9e-38 131.8 12.3 1.3 1 1 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 RLN97373.1 - 1.3e-05 24.7 2.5 1.3e-05 24.7 2.5 1.6 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain UBA PF00627.31 RLN97375.1 - 9.6e-12 44.6 0.1 2.9e-11 43.0 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain UCH PF00443.29 RLN97375.1 - 2.1e-10 40.6 0.0 2.7e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PH PF00169.29 RLN97375.1 - 0.0085 16.6 0.0 0.022 15.3 0.0 1.8 1 0 0 1 1 1 1 PH domain UBA_4 PF14555.6 RLN97375.1 - 0.019 14.8 0.1 0.045 13.6 0.1 1.6 1 0 0 1 1 1 0 UBA-like domain PDZ_6 PF17820.1 RLN97375.1 - 0.078 12.8 0.0 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 PDZ domain PHD_2 PF13831.6 RLN97376.1 - 1.1e-08 34.5 6.5 1.1e-08 34.5 6.5 2.5 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 RLN97376.1 - 1.9e-05 24.5 10.7 5.7e-05 22.9 10.7 1.8 1 0 0 1 1 1 1 PHD-finger WHIM1 PF15612.6 RLN97376.1 - 0.00061 19.3 0.5 0.0014 18.1 0.0 1.9 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 C1_1 PF00130.22 RLN97376.1 - 0.0085 16.0 8.3 0.021 14.7 4.4 2.3 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 RLN97376.1 - 0.17 11.5 11.1 0.052 13.2 3.9 2.6 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_2 PF03107.16 RLN97376.1 - 0.35 11.2 8.1 0.86 10.0 4.3 2.5 2 0 0 2 2 2 0 C1 domain TFIIA PF03153.13 RLN97376.1 - 6.7 6.6 12.6 2.8 7.8 8.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TFIIS_M PF07500.14 RLN97377.1 - 1.7e-19 70.4 0.5 3.5e-19 69.3 0.5 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 RLN97377.1 - 3.6e-17 61.9 4.3 5.8e-17 61.3 4.3 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 RLN97377.1 - 6.6e-12 45.3 1.4 6.6e-12 45.3 1.4 2.8 3 0 0 3 3 3 1 TFIIS helical bundle-like domain zf-DNL PF05180.12 RLN97377.1 - 0.0093 15.9 1.8 0.022 14.7 1.8 1.6 1 0 0 1 1 1 1 DNL zinc finger DUF2321 PF10083.9 RLN97377.1 - 0.089 12.4 1.2 0.21 11.2 1.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) EGF PF00008.27 RLN97378.1 - 0.0001 22.5 40.1 0.0015 18.8 1.3 4.5 4 0 0 4 4 4 3 EGF-like domain EGF_2 PF07974.13 RLN97378.1 - 0.00014 22.1 13.5 0.00014 22.1 13.5 4.8 5 1 0 5 5 5 3 EGF-like domain Complex1_51K PF01512.17 RLN97379.1 - 5.9e-47 159.3 0.0 1.4e-46 158.2 0.0 1.5 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit SLBB PF10531.9 RLN97379.1 - 0.016 15.0 0.0 0.067 13.1 0.0 2.1 2 0 0 2 2 2 0 SLBB domain Helitron_like_N PF14214.6 RLN97380.1 - 5.7e-11 43.0 0.1 1e-10 42.2 0.1 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DDE_1 PF03184.19 RLN97382.1 - 1.6e-08 34.4 0.0 2.3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Acetyltransf_10 PF13673.7 RLN97382.1 - 0.071 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sigma70_ECF PF07638.11 RLN97382.1 - 0.094 12.6 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 ECF sigma factor Stk19 PF10494.9 RLN97383.1 - 2.6e-19 69.9 0.5 4.6e-19 69.1 0.5 1.4 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 PseudoU_synth_1 PF01416.20 RLN97384.1 - 5.7e-11 42.8 0.3 5.7e-10 39.6 0.0 2.6 2 1 0 2 2 2 1 tRNA pseudouridine synthase Astro_capsid_p PF12226.8 RLN97384.1 - 0.48 9.5 6.0 0.82 8.8 6.0 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein GCV_H PF01597.19 RLN97385.1 - 4.7e-35 120.1 1.1 2.1e-21 76.1 0.1 2.1 2 0 0 2 2 2 2 Glycine cleavage H-protein CHDCT2 PF08074.11 RLN97386.1 - 0.078 13.1 2.9 3.6 7.7 1.3 2.3 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain zf-C2H2_12 PF18658.1 RLN97386.1 - 0.2 11.2 0.6 1.1 8.9 0.0 2.4 3 0 0 3 3 3 0 Zinc-finger C2H2-type MORN PF02493.20 RLN97388.1 - 1.2e-36 122.4 31.6 4e-05 23.3 0.2 9.4 9 0 0 9 9 9 8 MORN repeat Tim17 PF02466.19 RLN97388.1 - 4.4e-16 59.2 4.1 8.4e-16 58.3 4.1 1.5 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.9 RLN97388.1 - 0.21 11.7 4.9 9.5 6.4 1.1 2.7 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Romo1 PF10247.9 RLN97388.1 - 1.3 9.5 10.1 0.17 12.2 2.8 2.7 2 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Vasohibin PF14822.6 RLN97389.1 - 1.1e-59 201.7 0.1 1.4e-59 201.3 0.1 1.1 1 0 0 1 1 1 1 Vasohibin RNA_pol_Rpb1_5 PF04998.17 RLN97390.1 - 6.1e-94 314.4 0.1 1.1e-93 313.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 RLN97390.1 - 4e-65 219.1 0.1 7.1e-65 218.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 RLN97390.1 - 5.6e-33 114.1 0.0 5.4e-32 110.9 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 RLN97390.1 - 5.6e-19 68.1 0.0 1.9e-18 66.4 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.12 RLN97390.1 - 0.0027 17.1 0.6 0.26 10.6 0.1 3.1 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 DUF3043 PF11241.8 RLN97390.1 - 4.2 7.4 6.4 1 9.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) p25-alpha PF05517.12 RLN97391.1 - 0.021 15.0 0.0 0.066 13.4 0.0 1.8 2 0 0 2 2 2 0 p25-alpha PI3_PI4_kinase PF00454.27 RLN97395.1 - 2.2e-32 112.9 0.1 9.8e-25 87.8 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase FYVE PF01363.21 RLN97395.1 - 2.5e-06 27.5 15.2 2.5e-06 27.5 15.2 1.8 2 0 0 2 2 2 1 FYVE zinc finger DEP PF00610.21 RLN97395.1 - 3.8e-06 26.8 0.0 1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 RLN97395.1 - 0.0097 16.4 0.0 0.027 15.0 0.0 1.8 1 0 0 1 1 1 1 PH domain DUF4135 PF13575.6 RLN97395.1 - 0.013 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) IBR PF01485.21 RLN97395.1 - 0.037 14.3 5.7 0.12 12.6 5.7 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain AstE_AspA PF04952.14 RLN97396.1 - 9.6e-15 54.4 0.4 2.3e-14 53.1 0.4 1.5 1 1 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Peptidase_M14 PF00246.24 RLN97396.1 - 0.15 11.9 0.0 1 9.1 0.0 1.9 2 0 0 2 2 2 0 Zinc carboxypeptidase F_bP_aldolase PF01116.20 RLN97397.1 - 1.3e-89 300.4 0.0 1.5e-89 300.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II CPSase_L_D2 PF02786.17 RLN97397.1 - 0.11 12.0 0.5 0.82 9.1 0.2 2.0 1 1 1 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain His_Phos_2 PF00328.22 RLN97398.1 - 1.9e-24 86.7 0.2 6.1e-24 85.1 0.2 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF5375 PF17345.2 RLN97398.1 - 0.097 12.6 0.1 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5375) DisA_N PF02457.16 RLN97398.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding LRR_4 PF12799.7 RLN97399.1 - 8.6e-18 64.2 11.2 4.9e-05 23.6 0.1 3.8 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN97399.1 - 1.5e-16 60.4 4.7 4.2e-15 55.7 3.0 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 RLN97399.1 - 4.5e-10 39.1 18.7 7.3e-06 25.6 0.7 3.4 1 1 3 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 RLN97399.1 - 0.078 13.1 3.5 14 6.1 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 RLN97399.1 - 0.53 11.0 6.8 2e+02 3.2 0.2 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat ADH_zinc_N PF00107.26 RLN97400.1 - 1.6e-24 86.3 0.0 2.9e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RLN97400.1 - 1.1e-12 49.2 0.0 2.4e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN97400.1 - 6.3e-09 35.7 1.1 2.9e-08 33.6 0.7 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 RLN97400.1 - 0.011 16.0 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DSPc PF00782.20 RLN97403.1 - 7.9e-17 61.3 0.2 1e-16 60.9 0.2 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RLN97403.1 - 0.0007 19.2 0.1 0.00084 19.0 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 RLN97403.1 - 0.053 13.6 0.1 0.082 13.0 0.1 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Methyltransf_16 PF10294.9 RLN97404.1 - 7.5e-24 84.4 0.1 1.1e-23 83.8 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 RLN97404.1 - 3.5e-07 29.9 0.0 6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 RLN97404.1 - 0.00035 20.2 0.0 0.00059 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 RLN97404.1 - 0.0056 17.4 0.2 0.017 15.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 RLN97404.1 - 0.0069 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 RLN97404.1 - 0.025 14.4 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TPR_2 PF07719.17 RLN97405.1 - 8.4e-10 38.0 0.1 0.0012 18.8 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN97405.1 - 5.2e-09 36.3 0.6 0.00055 20.2 0.1 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat Glyco_transf_41 PF13844.6 RLN97405.1 - 4.4e-08 32.0 0.1 1e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 RLN97405.1 - 5.9e-07 29.0 0.0 0.095 12.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN97405.1 - 2.3e-05 24.1 0.1 0.13 12.4 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN97405.1 - 0.00032 20.9 0.1 4.9 7.7 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN97405.1 - 0.00038 20.1 0.0 0.25 11.0 0.0 3.2 2 1 1 3 3 3 1 TPR repeat TPR_8 PF13181.6 RLN97405.1 - 0.00057 19.9 0.0 6.7 7.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 RLN97405.1 - 0.0042 17.0 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 Virulence factor membrane-bound polymerase, C-terminal TPR_10 PF13374.6 RLN97405.1 - 0.0075 16.1 0.7 6.7 6.7 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN97405.1 - 0.2 12.6 2.8 39 5.4 0.0 4.3 3 2 2 5 5 3 0 Tetratricopeptide repeat cNMP_binding PF00027.29 RLN97406.1 - 1.6e-16 60.1 2.8 0.0029 17.6 0.0 7.5 6 2 0 6 6 6 6 Cyclic nucleotide-binding domain RecQ_Zn_bind PF16124.5 RLN97407.1 - 2.9e-18 66.3 7.8 6.3e-18 65.3 7.8 1.6 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 RLN97407.1 - 6.3e-10 38.8 0.4 2.2e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 RQC domain Pox_Ag35 PF03286.14 RLN97407.1 - 0.035 13.9 2.3 0.055 13.3 2.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Stm1_N PF09598.10 RLN97407.1 - 9.9 7.1 15.1 3.3 8.6 10.9 2.0 1 1 1 2 2 2 0 Stm1 DEAD PF00270.29 RLN97408.1 - 2.2e-17 63.4 0.0 4.5e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN97408.1 - 2.5e-09 37.5 0.0 9.1e-09 35.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-GRF PF06839.12 RLN97408.1 - 5.6e-05 23.1 1.0 0.00011 22.2 1.0 1.5 1 0 0 1 1 1 1 GRF zinc finger NBP1 PF08537.10 RLN97408.1 - 0.43 10.0 4.7 0.87 8.9 4.7 1.4 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Ogr_Delta PF04606.12 RLN97408.1 - 0.43 10.6 2.5 1.9 8.5 2.5 2.2 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger TPR_MLP1_2 PF07926.12 RLN97408.1 - 0.81 9.7 6.4 1.7 8.7 6.4 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3618 PF12277.8 RLN97408.1 - 1.7 8.9 4.9 2.6 8.4 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) MIB_HERC2 PF06701.13 RLN97409.1 - 0.093 13.0 0.3 0.24 11.7 0.0 1.9 2 0 0 2 2 2 0 Mib_herc2 DUF5414 PF17435.2 RLN97409.1 - 0.18 11.4 0.0 0.26 10.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5414) DUF3682 PF12446.8 RLN97409.1 - 2.2 8.8 17.2 2.2 8.8 3.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3682) GEN1_C PF18380.1 RLN97409.1 - 9.1 7.2 10.2 1.2 10.0 0.3 2.6 2 1 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Fascin PF06268.13 RLN97410.1 - 0.0011 19.2 0.1 0.0014 18.9 0.1 1.2 1 0 0 1 1 1 1 Fascin domain Lung_7-TM_R PF06814.13 RLN97412.1 - 2.7e-08 33.4 15.5 4.8e-08 32.6 15.5 1.3 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 RLN97412.1 - 3.2e-07 30.0 6.3 6.5e-07 29.0 6.3 1.5 1 1 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain GMP_synt_C PF00958.22 RLN97413.1 - 4.6e-43 145.2 0.0 1.2e-42 143.8 0.0 1.8 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 RLN97413.1 - 4.9e-31 108.0 0.0 7.5e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Pkinase PF00069.25 RLN97413.1 - 1.6e-14 53.9 0.0 2.6e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97413.1 - 3e-11 43.1 0.0 4.4e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NAD_synthase PF02540.17 RLN97413.1 - 2.4e-09 36.7 0.0 3e-07 29.8 0.0 2.3 2 0 0 2 2 2 1 NAD synthase Peptidase_C26 PF07722.13 RLN97413.1 - 2.6e-06 27.3 0.0 5.8e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 RLN97413.1 - 0.00022 20.1 0.0 0.00052 18.9 0.0 1.6 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 RLN97413.1 - 0.00027 20.6 0.0 0.00088 18.9 0.0 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 RLN97413.1 - 0.00058 19.9 0.0 0.0014 18.7 0.0 1.6 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family QueC PF06508.13 RLN97413.1 - 0.0023 17.5 0.0 0.052 13.1 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 RLN97413.1 - 0.036 13.3 0.1 0.055 12.7 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.20 RLN97413.1 - 0.084 12.6 0.1 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 PP-loop family FAA_hydrolase PF01557.18 RLN97414.1 - 6.5e-20 71.7 0.1 8e-20 71.4 0.1 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.17 RLN97414.1 - 0.15 11.9 0.2 0.15 11.9 0.2 1.5 2 0 0 2 2 2 0 KH domain FAA_hydrolase PF01557.18 RLN97415.1 - 2.2e-30 105.9 0.0 2.5e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Arm PF00514.23 RLN97416.1 - 8.3e-07 28.8 3.2 0.49 10.5 0.1 5.5 5 1 0 5 5 5 2 Armadillo/beta-catenin-like repeat IQ PF00612.27 RLN97416.1 - 0.0034 17.0 0.4 0.0093 15.7 0.4 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Gtr1_RagA PF04670.12 RLN97417.1 - 1.4e-27 96.5 1.5 7.4e-27 94.2 1.5 2.0 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 RLN97417.1 - 0.017 15.3 0.9 0.7 10.1 0.9 2.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Atu4866 PF11512.8 RLN97417.1 - 0.063 13.7 0.0 0.086 13.2 0.0 1.3 1 0 0 1 1 1 0 Agrobacterium tumefaciens protein Atu4866 Arf PF00025.21 RLN97417.1 - 0.065 12.7 0.1 0.18 11.2 0.1 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RLN97418.1 - 2.6e-47 161.1 0.4 3.3e-47 160.8 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF1279 PF06916.13 RLN97419.1 - 4.5e-23 81.6 0.6 6e-23 81.2 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) FAM163 PF15069.6 RLN97420.1 - 0.0031 18.0 0.1 0.0077 16.7 0.1 1.6 1 0 0 1 1 1 1 FAM163 family zinc_ribbon_10 PF10058.9 RLN97420.1 - 0.2 11.4 3.3 0.46 10.2 2.2 2.0 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Tnp_zf-ribbon_2 PF13842.6 RLN97420.1 - 1 10.2 5.9 2 9.3 5.9 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon HlyIII PF03006.20 RLN97422.1 - 8.3e-59 199.0 25.8 2e-52 178.1 21.3 2.0 2 0 0 2 2 2 2 Haemolysin-III related DUF962 PF06127.11 RLN97422.1 - 0.45 10.6 0.0 0.45 10.6 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF962) Amidase PF01425.21 RLN97423.1 - 0.007 15.4 0.2 0.0084 15.1 0.2 1.1 1 0 0 1 1 1 1 Amidase CLAMP PF14769.6 RLN97424.1 - 2.7e-08 34.2 0.0 6.1e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Flagellar C1a complex subunit C1a-32 CAP_N PF01213.19 RLN97425.1 - 6.7e-60 203.2 0.3 8.2e-59 199.6 0.0 2.3 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 RLN97425.1 - 9.5e-54 181.3 1.1 1.3e-53 180.8 1.1 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 RLN97425.1 - 0.0014 18.4 1.2 0.0031 17.2 1.2 1.6 1 1 0 1 1 1 1 Tubulin binding cofactor C RNA_lig_T4_1 PF09511.10 RLN97425.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 RNA ligase ThiS PF02597.20 RLN97427.1 - 6.9e-13 49.0 0.0 8e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 ThiS family Anoctamin PF04547.12 RLN97428.1 - 2.5e-48 165.1 0.4 9.6e-48 163.1 0.0 2.1 2 0 0 2 2 2 1 Calcium-activated chloride channel HTH_ABP1_N PF18107.1 RLN97430.1 - 1.1e-06 28.2 0.9 2.2e-06 27.3 0.9 1.5 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain DDE_Tnp_1_assoc PF13808.6 RLN97430.1 - 0.067 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 DDE_Tnp_1-associated 5_nucleotid_C PF02872.18 RLN97432.1 - 7.7e-21 74.9 0.0 4.6e-20 72.4 0.0 2.3 1 1 1 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 RLN97432.1 - 2.3e-10 41.3 0.2 1.7e-09 38.4 0.1 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase ABC_tran PF00005.27 RLN97433.1 - 9.5e-19 68.3 0.0 7.2e-16 58.9 0.0 2.1 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN97433.1 - 0.00022 20.7 0.0 0.00027 20.5 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Mob_synth_C PF06463.13 RLN97434.1 - 3.4e-37 127.2 0.0 9.1e-37 125.9 0.0 1.7 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 RLN97434.1 - 5.9e-29 101.6 0.0 1.1e-28 100.7 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 RLN97434.1 - 1.7e-09 38.1 0.0 4e-09 36.9 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 RLN97434.1 - 0.00025 21.1 0.0 0.00053 20.1 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain BHD_3 PF10405.9 RLN97435.1 - 4.6e-24 84.6 0.0 8.3e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 RLN97435.1 - 1.1e-18 67.3 0.0 2.4e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 RLN97435.1 - 1.6e-16 59.8 0.0 2.9e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 RLN97435.1 - 5e-11 43.4 2.4 1.3e-10 42.0 0.1 3.0 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 RLN97435.1 - 0.015 15.7 0.1 0.042 14.3 0.1 1.8 1 1 0 1 1 1 0 Transglutaminase-like superfamily cNMP_binding PF00027.29 RLN97436.1 - 1.9e-19 69.5 0.0 3.4e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain ADP_PFK_GK PF04587.15 RLN97436.1 - 0.026 13.1 0.1 0.04 12.5 0.1 1.2 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Glyco_hydro_17 PF00332.18 RLN97437.1 - 2e-05 24.3 0.1 0.0051 16.4 0.0 2.5 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Arm PF00514.23 RLN97438.1 - 4.1e-42 141.0 6.0 7.8e-06 25.7 0.0 6.7 6 1 1 7 7 7 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN97438.1 - 1.5e-17 63.7 9.5 5.3e-05 23.6 0.2 5.9 4 2 2 6 6 6 5 HEAT-like repeat HEAT PF02985.22 RLN97438.1 - 2.2e-16 58.5 4.8 0.49 10.8 0.0 6.3 6 0 0 6 6 6 5 HEAT repeat HEAT_2 PF13646.6 RLN97438.1 - 4.3e-11 43.1 21.5 0.00062 20.1 0.8 3.5 1 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 RLN97438.1 - 3.9e-06 27.0 22.9 3.3 8.6 0.3 6.6 6 0 0 6 6 6 2 PBS lyase HEAT-like repeat Tox-MPTase3 PF15639.6 RLN97438.1 - 0.00025 20.9 0.1 13 5.6 0.0 4.5 1 1 4 5 5 5 0 Metallopeptidase toxin 3 PfaD_N PF18328.1 RLN97438.1 - 0.00048 20.0 1.2 1.2e+02 2.7 0.0 5.1 5 0 0 5 5 5 0 Fatty acid synthase subunit PfaD N-terminal domain NFACT-R_2 PF18297.1 RLN97438.1 - 0.0007 19.8 1.4 31 4.8 0.0 4.4 1 1 4 5 5 5 0 NFACT protein RNA binding domain Atx10homo_assoc PF09759.9 RLN97438.1 - 0.0015 18.5 0.0 2.4 8.2 0.0 3.6 3 1 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain NgoMIV_restric PF09015.10 RLN97438.1 - 0.0036 16.5 2.3 2 7.4 0.1 3.3 1 1 4 5 5 5 2 NgoMIV restriction enzyme T6SS_VasJ PF16989.5 RLN97438.1 - 0.0049 16.4 2.0 3.9 6.9 0.3 3.2 1 1 2 3 3 3 2 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ DUF294_C PF10335.9 RLN97438.1 - 0.012 15.4 3.8 7.5 6.3 0.0 5.0 1 1 4 6 6 6 0 Putative nucleotidyltransferase substrate binding domain ATP-synt_F PF01990.17 RLN97438.1 - 0.039 14.3 4.4 50 4.3 0.2 4.5 2 1 2 4 4 3 0 ATP synthase (F/14-kDa) subunit Succ_CoA_lig PF13607.6 RLN97438.1 - 0.086 12.6 5.9 46 3.8 0.1 4.5 1 1 4 5 5 5 0 Succinyl-CoA ligase like flavodoxin domain DUF3247 PF11607.8 RLN97438.1 - 0.11 12.8 2.2 1.3e+02 3.0 0.0 4.4 1 1 4 5 5 5 0 Protein of unknown function (DUF3247) GH97_C PF14509.6 RLN97438.1 - 0.31 11.3 8.2 82 3.5 0.1 4.5 1 1 4 5 5 5 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation Tex_N PF09371.10 RLN97438.1 - 0.63 9.7 5.6 98 2.6 0.1 4.1 1 1 4 5 5 5 0 Tex-like protein N-terminal domain UCR_14kD PF02271.16 RLN97438.1 - 0.65 10.0 9.3 84 3.2 0.1 4.3 5 0 0 5 5 4 0 Ubiquinol-cytochrome C reductase complex 14kD subunit PGM_PMM_II PF02879.16 RLN97438.1 - 0.69 10.6 11.7 33 5.2 0.1 4.9 5 0 0 5 5 5 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II bPH_6 PF10756.9 RLN97438.1 - 2.5 8.2 11.8 64 3.7 0.2 4.7 5 1 0 5 5 4 0 Bacterial PH domain cNMP_binding PF00027.29 RLN97439.1 - 2.2e-25 88.5 0.3 5.6e-12 45.6 0.1 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN97439.1 - 0.00054 19.3 8.6 0.005 16.1 0.1 2.4 2 0 0 2 2 2 2 Ion transport protein TMEM192 PF14802.6 RLN97439.1 - 0.11 11.5 4.2 0.82 8.7 0.8 3.0 3 0 0 3 3 3 0 TMEM192 family DDE_1 PF03184.19 RLN97440.1 - 0.026 14.2 0.0 0.049 13.3 0.0 1.4 1 1 0 1 1 1 0 DDE superfamily endonuclease Pkinase_Tyr PF07714.17 RLN97441.1 - 2.3e-51 174.6 0.0 3.1e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN97441.1 - 4.5e-49 167.2 0.0 6.3e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 RLN97441.1 - 0.0015 18.5 0.1 0.0086 16.0 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN97441.1 - 0.027 13.3 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 RLN97441.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2755 PF10954.8 RLN97441.1 - 0.22 11.5 1.3 2.9 7.9 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2755) Pkinase_Tyr PF07714.17 RLN97442.1 - 8e-36 123.6 0.0 1.2e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN97442.1 - 2.3e-29 102.6 0.0 3.4e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TMEM154 PF15102.6 RLN97442.1 - 0.0072 16.2 0.1 0.3 11.0 0.0 2.3 1 1 1 2 2 2 1 TMEM154 protein family Herpes_gE PF02480.16 RLN97442.1 - 0.013 14.3 0.0 0.022 13.5 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CEND1 PF15677.5 RLN97442.1 - 0.023 15.2 0.1 0.064 13.8 0.1 1.8 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 Rax2 PF12768.7 RLN97442.1 - 0.062 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Cortical protein marker for cell polarity P53_TAD PF08563.11 RLN97442.1 - 6.6 6.3 6.9 0.89 9.1 1.6 2.4 2 0 0 2 2 2 0 P53 transactivation motif Pkinase_Tyr PF07714.17 RLN97443.1 - 6.3e-41 140.4 0.0 8.1e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN97443.1 - 3.1e-38 131.7 0.0 4.8e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 RLN97443.1 - 0.076 12.9 0.1 0.27 11.1 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN97443.1 - 0.19 10.6 0.0 0.45 9.4 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 RLN97443.1 - 0.21 10.9 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PA PF02225.22 RLN97444.1 - 0.00012 22.1 0.3 0.0068 16.4 0.1 2.7 3 0 0 3 3 3 2 PA domain ANAPC3 PF12895.7 RLN97447.1 - 0.00015 22.0 6.4 0.00038 20.6 1.6 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 RLN97447.1 - 0.29 11.0 2.7 13 5.8 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 RLN97447.1 - 0.35 11.1 13.8 1.1 9.6 0.4 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN97447.1 - 0.61 11.0 8.7 15 6.7 1.7 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN97447.1 - 2.4 8.9 8.3 5.6 7.7 1.3 2.9 1 1 0 2 2 2 0 Tetratricopeptide repeat DDE_3 PF13358.6 RLN97448.1 - 2.4e-12 46.8 0.2 2e-08 34.1 0.2 3.6 2 1 0 2 2 2 2 DDE superfamily endonuclease DNA_meth_N PF18284.1 RLN97448.1 - 3.5 7.6 11.0 5.9 6.9 0.0 3.5 2 1 1 3 3 3 0 DNA methylase N-terminal domain Ank_2 PF12796.7 RLN97449.1 - 1.2e-24 86.6 2.1 5.3e-10 39.7 0.1 3.9 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN97449.1 - 1.4e-17 63.8 0.2 1.8e-10 41.1 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN97449.1 - 3.6e-16 59.0 0.7 3.9e-08 33.4 0.0 4.2 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN97449.1 - 1.3e-14 53.9 0.1 0.0007 19.9 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 RLN97449.1 - 1.8e-12 46.3 0.1 0.017 15.6 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat AAA_9 PF12781.7 RLN97449.1 - 4e-05 22.8 0.2 0.00012 21.3 0.0 1.9 2 0 0 2 2 2 1 ATP-binding dynein motor region IDEAL PF08858.10 RLN97449.1 - 0.031 14.0 0.2 0.065 13.0 0.2 1.5 1 0 0 1 1 1 0 IDEAL domain SICA_C PF12879.7 RLN97449.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 SICA C-terminal inner membrane domain HECT PF00632.25 RLN97450.1 - 8.9e-57 192.9 0.0 1.7e-56 192.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MRI PF15325.6 RLN97450.1 - 0.24 12.5 1.8 8 7.6 0.5 3.2 2 0 0 2 2 2 0 Modulator of retrovirus infection PX PF00787.24 RLN97453.1 - 2.2e-05 24.4 0.1 4.4e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 PX domain PCRF PF03462.18 RLN97454.1 - 1.1e-53 182.0 0.2 2.1e-53 181.1 0.2 1.4 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 RLN97454.1 - 8.9e-38 128.8 0.8 8.9e-38 128.8 0.8 2.1 2 0 0 2 2 2 1 RF-1 domain DUF572 PF04502.13 RLN97454.1 - 0.057 13.0 3.7 0.026 14.2 1.5 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF1840 PF08895.11 RLN97454.1 - 0.2 12.0 4.6 0.13 12.6 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) DUF1204 PF06721.11 RLN97456.1 - 0.0077 15.7 1.3 0.0077 15.7 1.3 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1204) DUF1664 PF07889.12 RLN97456.1 - 0.013 15.5 18.7 2 8.5 0.0 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF4795 PF16043.5 RLN97456.1 - 0.24 11.0 28.1 0.23 11.0 8.7 4.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4795) YusW PF14039.6 RLN97456.1 - 2.9 8.5 6.9 6.2 7.4 0.2 3.3 2 1 1 3 3 3 0 YusW-like protein Occludin_ELL PF07303.13 RLN97456.1 - 4 8.2 24.8 6.7 7.5 2.9 5.3 3 2 2 5 5 5 0 Occludin homology domain Phage_TAC_4 PF08748.11 RLN97456.1 - 4 7.8 12.7 0.032 14.6 1.7 2.7 2 1 0 2 2 2 0 Phage tail assembly chaperone MutS_IV PF05190.18 RLN97456.1 - 8.9 6.7 9.8 6.9 7.1 0.1 3.9 3 1 1 4 4 4 0 MutS family domain IV DUSP PF06337.12 RLN97457.1 - 2.8e-08 34.2 0.0 7.4e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 DUSP domain Tudor-knot PF11717.8 RLN97457.1 - 0.0033 17.3 0.3 0.0094 15.8 0.3 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MBT PF02820.18 RLN97457.1 - 0.0082 16.5 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 mbt repeat Tudor_4 PF18358.1 RLN97457.1 - 0.021 14.4 0.3 0.11 12.1 0.3 2.2 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain DUF1818 PF08848.11 RLN97457.1 - 4.7 7.3 8.9 0.85 9.7 3.6 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1818) Acetate_kinase PF00871.17 RLN97458.1 - 3.8e-139 463.7 0.0 4.4e-139 463.5 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family Arm PF00514.23 RLN97459.1 - 7.4e-21 73.5 0.2 1.3e-06 28.3 0.0 4.4 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 RLN97459.1 - 7e-05 23.1 5.2 3.1 8.7 0.1 4.0 3 1 0 3 3 3 3 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 RLN97459.1 - 0.00015 21.7 0.5 0.022 14.8 0.0 3.2 2 2 1 3 3 3 1 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 RLN97459.1 - 0.0039 17.7 3.4 0.071 13.6 0.3 3.4 3 1 0 3 3 3 1 HEAT-like repeat HEAT_2 PF13646.6 RLN97459.1 - 0.011 16.1 2.8 0.046 14.1 0.5 2.4 1 1 1 2 2 2 0 HEAT repeats UNC45-central PF11701.8 RLN97459.1 - 0.028 14.4 0.0 0.49 10.4 0.0 2.1 1 1 1 2 2 2 0 Myosin-binding striated muscle assembly central NadA PF02445.16 RLN97460.1 - 9.7e-34 116.9 0.1 1.1e-32 113.4 0.2 2.0 2 0 0 2 2 2 1 Quinolinate synthetase A protein MRP-S33 PF08293.11 RLN97460.1 - 0.019 15.2 0.0 0.081 13.2 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit S27 Arm PF00514.23 RLN97461.1 - 1e-55 184.1 16.5 3.8e-08 33.1 0.1 12.2 11 1 1 12 12 12 10 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RLN97461.1 - 1.4e-12 47.8 25.0 0.0011 19.4 0.2 8.9 6 4 5 11 11 11 5 HEAT-like repeat Atx10homo_assoc PF09759.9 RLN97461.1 - 5.7e-11 42.3 4.5 0.044 13.8 0.0 5.7 3 3 1 5 5 5 3 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 RLN97461.1 - 9.9e-10 38.2 32.4 3.5 8.6 0.5 11.4 11 0 0 11 11 11 3 PBS lyase HEAT-like repeat HEAT_2 PF13646.6 RLN97461.1 - 6.1e-09 36.1 28.9 0.011 16.1 0.1 5.8 2 2 4 6 6 6 5 HEAT repeats HEAT PF02985.22 RLN97461.1 - 1.3e-08 34.4 9.9 3.5 8.1 0.0 9.4 10 0 0 10 10 10 2 HEAT repeat UNC45-central PF11701.8 RLN97461.1 - 5.6e-05 23.1 0.1 3.9 7.4 0.0 4.0 2 1 2 4 4 4 2 Myosin-binding striated muscle assembly central V-ATPase_H_N PF03224.14 RLN97461.1 - 0.0084 15.4 0.0 5.9 6.1 0.0 2.9 1 1 0 2 2 2 2 V-ATPase subunit H Nuc_N PF14448.6 RLN97461.1 - 0.22 11.4 1.8 98 2.9 0.0 4.9 5 1 1 6 6 6 0 Nuclease N terminal DUF5308 PF17233.2 RLN97461.1 - 1.8 8.8 9.2 9.3 6.5 0.3 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5308) Pkinase PF00069.25 RLN97462.1 - 1.1e-40 139.7 0.0 8.2e-39 133.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97462.1 - 5.6e-38 130.7 0.0 3.5e-35 121.5 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 RLN97462.1 - 1.3e-05 25.3 0.1 0.00096 19.1 0.0 3.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF2890 PF11081.8 RLN97463.1 - 0.52 10.4 4.0 0.81 9.8 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CorA PF01544.18 RLN97464.1 - 7.3e-44 150.2 0.1 1.5e-38 132.8 0.0 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein EF-hand_7 PF13499.6 RLN97464.1 - 0.0002 21.7 0.1 0.00044 20.7 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN97464.1 - 0.00094 18.6 0.1 0.0018 17.7 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 RLN97464.1 - 0.013 15.3 0.1 0.025 14.4 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair ATP_bind_2 PF03668.15 RLN97464.1 - 0.015 14.6 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 P-loop ATPase protein family EF-hand_6 PF13405.6 RLN97464.1 - 0.029 14.3 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain SAM_2 PF07647.17 RLN97465.1 - 1.5e-14 53.8 0.0 3.8e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RLN97465.1 - 1.8e-14 53.9 0.1 3.4e-14 53.0 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IQ PF00612.27 RLN97465.1 - 5.7e-11 41.2 40.8 0.0095 15.7 3.0 7.3 7 0 0 7 7 7 5 IQ calmodulin-binding motif Response_reg PF00072.24 RLN97465.1 - 1.9e-07 31.3 0.0 4.6e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain FAM76 PF16046.5 RLN97465.1 - 0.76 9.1 6.1 2 7.7 6.1 1.7 1 0 0 1 1 1 0 FAM76 protein Glyco_hydro_72 PF03198.14 RLN97466.1 - 1.5e-55 188.7 2.7 2.3e-55 188.1 2.7 1.2 1 0 0 1 1 1 1 Glucanosyltransferase RPN2_C PF18004.1 RLN97467.1 - 5.3 6.9 9.2 6.9 6.6 9.2 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain BUD22 PF09073.10 RLN97467.1 - 6.5 6.0 30.5 7.3 5.8 30.5 1.0 1 0 0 1 1 1 0 BUD22 BUD22 PF09073.10 RLN97468.1 - 0.16 11.2 4.9 0.2 11.0 4.9 1.1 1 0 0 1 1 1 0 BUD22 IML1 PF12257.8 RLN97473.1 - 1.1e-80 270.9 0.0 1.5e-80 270.4 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 Cornichon PF03311.14 RLN97474.1 - 3.8e-11 43.4 0.2 0.00017 21.9 0.1 2.1 1 1 1 2 2 2 2 Cornichon protein URO-D PF01208.17 RLN97475.1 - 3.7e-123 411.1 0.0 4.3e-123 410.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PMP1_2 PF08114.11 RLN97475.1 - 0.13 12.0 0.1 0.34 10.7 0.1 1.7 1 0 0 1 1 1 0 ATPase proteolipid family Baculo_PEP_C PF04513.12 RLN97476.1 - 0.0043 17.1 10.9 1.6 8.7 2.9 3.4 3 1 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 RLN97476.1 - 0.0077 15.6 1.2 0.0077 15.6 1.2 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) DUF883 PF05957.13 RLN97476.1 - 0.021 15.4 1.7 0.021 15.4 1.7 4.8 2 2 3 5 5 5 0 Bacterial protein of unknown function (DUF883) Allexi_40kDa PF05549.11 RLN97476.1 - 0.55 9.7 18.3 2.1 7.8 3.7 3.0 2 1 1 3 3 3 0 Allexivirus 40kDa protein DUF1664 PF07889.12 RLN97476.1 - 0.62 10.1 23.7 0.9 9.6 0.3 4.3 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Tup_N PF08581.10 RLN97476.1 - 0.79 10.1 24.5 0.46 10.8 2.8 5.0 4 2 1 5 5 5 0 Tup N-terminal Jnk-SapK_ap_N PF09744.9 RLN97476.1 - 1.5 9.0 29.9 0.59 10.4 0.6 3.2 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 PIP5K PF01504.18 RLN97476.1 - 1.7 7.8 6.8 0.17 11.0 0.7 2.1 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase HAP1_N PF04849.13 RLN97476.1 - 2.1 7.5 24.4 0.12 11.6 8.7 2.7 2 1 0 2 2 2 0 HAP1 N-terminal conserved region Fib_alpha PF08702.10 RLN97476.1 - 2.3 8.4 15.0 0.11 12.7 2.9 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family COQ9 PF08511.11 RLN97477.1 - 3.1e-35 119.8 0.2 6e-35 118.9 0.2 1.5 1 0 0 1 1 1 1 COQ9 PseudoU_synth_1 PF01416.20 RLN97478.1 - 1.6e-32 112.2 0.0 3.1e-29 101.6 0.0 2.6 2 1 0 2 2 2 2 tRNA pseudouridine synthase PP2C PF00481.21 RLN97479.1 - 2e-62 211.1 0.1 3e-62 210.6 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RLN97479.1 - 0.00093 18.9 1.8 0.0019 17.9 1.7 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C AlgF PF11182.8 RLN97479.1 - 0.047 13.5 0.2 0.12 12.1 0.1 1.7 2 0 0 2 2 2 0 Alginate O-acetyl transferase AlgF ACT PF01842.25 RLN97479.1 - 0.11 12.3 0.2 1.8 8.4 0.0 2.6 2 0 0 2 2 2 0 ACT domain MAPEG PF01124.18 RLN97480.1 - 5.8e-33 113.6 3.7 2.3e-16 59.9 0.2 2.1 2 0 0 2 2 2 2 MAPEG family DUF2207 PF09972.9 RLN97480.1 - 0.19 10.4 0.0 0.31 9.7 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TctB PF07331.11 RLN97480.1 - 6.5 7.0 8.7 10 6.4 0.5 3.4 3 1 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family MAPEG PF01124.18 RLN97481.1 - 3.8e-19 68.9 0.9 5.8e-19 68.3 0.9 1.2 1 0 0 1 1 1 1 MAPEG family Mtc PF03820.17 RLN97482.1 - 9.1e-19 67.6 0.5 2.6e-09 36.6 0.0 3.0 1 1 2 3 3 3 3 Tricarboxylate carrier EF-hand_7 PF13499.6 RLN97483.1 - 2.8e-05 24.5 0.6 0.00037 20.9 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN97483.1 - 6.2e-05 22.3 0.1 0.00013 21.3 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 RLN97483.1 - 0.00012 21.7 0.6 0.0015 18.3 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 RLN97483.1 - 0.00016 21.0 0.4 0.00058 19.2 0.0 2.0 2 0 0 2 2 2 1 EF hand YPEB PF14620.6 RLN97483.1 - 0.0091 15.4 0.7 0.0091 15.4 0.7 1.5 2 0 0 2 2 2 1 YpeB sporulation SPARC_Ca_bdg PF10591.9 RLN97483.1 - 0.012 16.0 0.2 0.026 14.8 0.1 1.7 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Spc7 PF08317.11 RLN97483.1 - 0.054 12.4 3.9 0.4 9.5 0.7 2.6 3 0 0 3 3 3 0 Spc7 kinetochore protein zf-CpG_bind_C PF12269.8 RLN97483.1 - 0.071 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain AICARFT_IMPCHas PF01808.18 RLN97484.1 - 8e-74 248.7 0.0 1.1e-73 248.3 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme CtsR PF05848.11 RLN97484.1 - 0.095 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 CtsR N-terminal HTH domain PSS PF03034.15 RLN97485.1 - 6.1e-104 347.6 13.7 8.2e-104 347.2 13.7 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase PsbN PF02468.15 RLN97485.1 - 0.016 15.0 0.0 0.054 13.4 0.0 1.9 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) Dimer_Tnp_hAT PF05699.14 RLN97486.1 - 0.031 14.1 0.0 0.096 12.5 0.0 1.8 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region PI3_PI4_kinase PF00454.27 RLN97487.1 - 1.3e-52 179.2 0.0 2.3e-52 178.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 RLN97487.1 - 8e-48 162.3 2.3 1.6e-47 161.3 2.3 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 RLN97487.1 - 0.064 12.6 0.0 0.15 11.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) PI3K_C2 PF00792.24 RLN97487.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 CRT-like PF08627.10 RLN97488.1 - 2.6e-10 39.8 0.7 2.6e-10 39.8 0.7 2.2 1 1 1 2 2 2 2 CRT-like, chloroquine-resistance transporter-like MORN PF02493.20 RLN97489.1 - 4.2e-21 73.5 27.9 8.6e-05 22.2 0.1 6.9 7 1 0 7 7 7 6 MORN repeat DUF4961 PF16328.5 RLN97489.1 - 0.3 10.3 0.0 0.51 9.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4961) DNA_primase_lrg PF04104.14 RLN97490.1 - 5.1e-63 212.9 0.0 6.1e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit 2OG-FeII_Oxy PF03171.20 RLN97491.1 - 7.8e-05 23.1 0.0 0.00013 22.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PH PF00169.29 RLN97493.1 - 0.0016 18.9 0.0 0.0032 17.9 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN97493.1 - 0.094 13.0 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Got1 PF04178.12 RLN97494.1 - 7.1e-31 107.0 14.1 9.2e-31 106.6 14.1 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family LEA_5 PF00477.17 RLN97494.1 - 0.037 14.5 0.2 0.051 14.1 0.2 1.2 1 0 0 1 1 1 0 Small hydrophilic plant seed protein PCI PF01399.27 RLN97495.1 - 6.5e-16 58.7 2.3 7.5e-16 58.5 0.6 2.0 2 0 0 2 2 2 1 PCI domain TPR_7 PF13176.6 RLN97495.1 - 6.6e-05 22.7 0.4 0.83 9.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 RLN97495.1 - 0.0012 18.9 0.1 0.0031 17.5 0.1 1.7 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family TPR_12 PF13424.6 RLN97495.1 - 0.004 17.4 0.2 2.5 8.4 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN97495.1 - 0.0081 16.0 0.4 0.095 12.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 RLN97495.1 - 0.015 15.3 0.3 0.091 12.9 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN97495.1 - 0.029 15.2 0.1 1.9 9.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat YL1 PF05764.13 RLN97495.1 - 0.32 11.1 3.5 0.47 10.5 3.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Phos_pyr_kin PF08543.12 RLN97496.1 - 3.1e-11 43.2 0.0 2.6e-10 40.1 0.0 2.1 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 RLN97496.1 - 3.7e-09 36.3 0.0 3.7e-06 26.5 0.0 2.5 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Utp14 PF04615.13 RLN97497.1 - 3 6.3 7.2 3.5 6.1 7.2 1.1 1 0 0 1 1 1 0 Utp14 protein Plasmodium_Vir PF05795.11 RLN97497.1 - 6.9 6.0 8.7 12 5.2 8.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Pkinase PF00069.25 RLN97499.1 - 1.1e-49 169.2 0.0 1.3e-49 169.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97499.1 - 1e-30 106.9 0.0 1.4e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN97499.1 - 3.3e-05 22.8 0.0 4.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN97499.1 - 0.00051 19.5 0.0 0.00067 19.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN97499.1 - 0.002 18.1 0.5 0.17 11.7 0.2 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 RLN97499.1 - 0.02 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 RLN97499.1 - 0.033 13.5 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CorA PF01544.18 RLN97500.1 - 2e-51 175.0 0.1 1.4e-43 149.3 0.0 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein EF-hand_7 PF13499.6 RLN97500.1 - 0.00029 21.2 0.3 0.0016 18.9 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN97500.1 - 0.0029 17.0 0.1 0.0082 15.6 0.1 1.8 1 0 0 1 1 1 1 EF hand ATP_bind_2 PF03668.15 RLN97500.1 - 0.0033 16.8 0.1 0.0053 16.1 0.1 1.2 1 0 0 1 1 1 1 P-loop ATPase protein family EF-hand_8 PF13833.6 RLN97500.1 - 0.021 14.7 0.1 0.021 14.7 0.1 2.1 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_6 PF13405.6 RLN97500.1 - 0.11 12.4 0.0 0.46 10.5 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain WD40 PF00400.32 RLN97501.1 - 2.3e-22 78.9 28.5 7.8e-05 23.4 0.4 10.0 11 1 0 11 11 11 5 WD domain, G-beta repeat EF-hand_1 PF00036.32 RLN97501.1 - 0.0027 17.1 1.1 0.0069 15.9 0.1 2.2 2 0 0 2 2 2 1 EF hand Nup160 PF11715.8 RLN97501.1 - 0.005 15.6 0.0 2.2 6.8 0.0 3.2 3 0 0 3 3 3 2 Nucleoporin Nup120/160 EF-hand_7 PF13499.6 RLN97501.1 - 0.0087 16.5 0.1 0.021 15.3 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RLN97501.1 - 0.01 15.3 0.2 0.024 14.1 0.2 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 RLN97501.1 - 0.056 13.4 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain Spt20 PF12090.8 RLN97502.1 - 0.5 9.9 6.2 2 8.0 0.0 2.4 1 1 1 2 2 2 0 Spt20 family DUF1542 PF07564.11 RLN97502.1 - 0.52 10.5 4.6 0.21 11.7 1.4 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Abhydrolase_6 PF12697.7 RLN97504.1 - 6e-14 53.2 2.0 7.3e-14 52.9 2.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN97504.1 - 0.00025 20.4 0.0 0.00047 19.5 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN97505.1 - 1.1e-14 55.5 0.7 1.5e-14 55.1 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN97505.1 - 0.00096 18.5 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN97506.1 - 1.6e-11 45.2 0.2 1.9e-11 45.0 0.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN97506.1 - 2.7e-05 23.6 0.0 4.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN97506.1 - 0.014 15.1 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN97507.1 - 1.6e-12 48.5 0.4 2.2e-12 48.1 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN97507.1 - 5e-06 25.9 0.0 0.00033 20.0 0.0 2.5 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN97507.1 - 0.049 13.3 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold ER PF01133.17 RLN97508.1 - 2.2e-37 127.0 1.1 1.3e-36 124.6 1.1 1.8 1 1 0 1 1 1 1 Enhancer of rudimentary Chordopox_RPO7 PF05864.12 RLN97508.1 - 0.079 13.2 0.6 0.17 12.2 0.6 1.5 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) VP4_helical PF17478.2 RLN97509.1 - 0.0015 18.0 0.0 0.0018 17.8 0.0 1.0 1 0 0 1 1 1 1 Rotavirus VP4 helical domain Apolipoprotein PF01442.18 RLN97509.1 - 0.081 12.8 4.3 0.11 12.4 4.3 1.3 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain GAS PF13851.6 RLN97509.1 - 0.097 12.0 0.6 0.36 10.2 0.1 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HIRAN PF08797.11 RLN97509.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 1 0 1 1 1 0 HIRAN domain NTF2 PF02136.20 RLN97510.1 - 3.6e-27 95.3 0.5 4e-27 95.1 0.5 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Dimeth_Pyl PF09505.10 RLN97510.1 - 0.12 10.9 0.0 0.12 10.8 0.0 1.0 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) Skp1_POZ PF03931.15 RLN97511.1 - 7.4e-07 29.3 0.0 0.011 15.9 0.0 2.4 1 1 1 2 2 2 2 Skp1 family, tetramerisation domain BTB PF00651.31 RLN97511.1 - 0.076 13.2 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain FSH1 PF03959.13 RLN97513.1 - 4e-24 85.5 0.0 4.9e-22 78.6 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 RLN97513.1 - 0.043 13.6 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DLH PF01738.18 RLN97513.1 - 0.21 11.1 0.0 0.6 9.6 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family ABC_transp_aux PF09822.9 RLN97514.1 - 2.1e-05 24.1 0.0 3.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DDOST_48kD PF03345.14 RLN97514.1 - 0.0022 16.9 0.0 0.012 14.5 0.0 1.9 2 0 0 2 2 2 1 Oligosaccharyltransferase 48 kDa subunit beta DUF4686 PF15742.5 RLN97514.1 - 0.11 11.6 0.2 0.17 11.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) TssN PF17555.2 RLN97515.1 - 0.13 11.7 3.9 0.43 9.9 0.1 2.5 2 0 0 2 2 2 0 Type VI secretion system, TssN COX14 PF14880.6 RLN97516.1 - 0.0076 16.1 1.7 6.3 6.7 0.0 3.5 3 0 0 3 3 3 2 Cytochrome oxidase c assembly DUF416 PF04222.12 RLN97516.1 - 0.049 13.1 0.1 0.076 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF416) NADH-u_ox-rdase PF10785.9 RLN97516.1 - 3.9 8.2 5.1 5.1 7.9 0.2 3.0 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Ras PF00071.22 RLN97517.1 - 9.7e-19 67.5 0.0 1.1e-18 67.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN97517.1 - 4.5e-14 52.7 0.0 5.5e-14 52.4 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 RLN97517.1 - 0.00013 22.0 0.0 0.00016 21.7 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RLN97517.1 - 0.01 15.2 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 RLN97517.1 - 0.032 14.0 0.0 0.056 13.2 0.0 1.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 RLN97517.1 - 0.094 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B UL41A PF17591.2 RLN97518.1 - 0.12 12.4 1.3 1.3 9.2 0.1 2.7 2 1 0 2 2 2 0 Herpesvirus UL41A HMG_box PF00505.19 RLN97519.1 - 2.4e-36 124.0 12.4 1.2e-19 70.5 3.3 2.9 4 0 0 4 4 4 2 HMG (high mobility group) box HMG_box_2 PF09011.10 RLN97519.1 - 6.5e-26 90.7 12.0 1.2e-12 48.2 3.4 2.6 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 RLN97519.1 - 0.046 13.7 12.7 0.2 11.7 1.4 2.8 1 1 1 2 2 2 0 HMG (high mobility group) box 5 Ccdc124 PF06244.12 RLN97519.1 - 2.4 8.7 14.0 0.44 11.1 6.0 2.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 PGK PF00162.19 RLN97520.1 - 3.5e-147 490.3 6.9 3.9e-147 490.1 6.9 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 RLN97520.1 - 0.00037 20.5 1.8 0.022 14.8 0.0 3.6 2 2 2 4 4 4 1 PA domain Asp PF00026.23 RLN97521.1 - 1.1e-45 156.4 0.0 1.3e-45 156.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RLN97521.1 - 2.8e-10 40.7 0.2 9.6e-07 29.2 0.0 2.1 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 RLN97521.1 - 0.02 15.6 0.0 0.047 14.3 0.0 1.7 1 1 0 1 1 1 0 Aspartyl protease PHF5 PF03660.14 RLN97522.1 - 3.8e-49 165.2 11.8 6.3e-49 164.5 11.8 1.3 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 RLN97522.1 - 0.059 11.2 4.0 0.08 10.8 4.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Prok-RING_4 PF14447.6 RLN97522.1 - 9.4 6.2 11.5 21 5.1 5.3 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Pkinase PF00069.25 RLN97523.1 - 1.3e-68 231.2 0.0 1.7e-68 230.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97523.1 - 3e-36 125.0 0.0 7.7e-36 123.7 0.0 1.6 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN97523.1 - 2.1e-06 27.3 0.0 2.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN97523.1 - 2.6e-06 27.0 0.0 4.6e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN97523.1 - 6.7e-05 21.8 0.0 0.00025 20.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 RLN97523.1 - 0.0014 18.6 5.1 0.01 15.7 2.7 3.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 RLN97523.1 - 0.0061 16.2 0.0 0.016 14.8 0.0 1.6 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 RLN97523.1 - 0.038 13.6 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 RLN97523.1 - 0.065 12.8 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PGA2 PF07543.12 RLN97524.1 - 5.3e-05 23.2 6.9 5.3e-05 23.2 6.9 2.5 3 0 0 3 3 3 1 Protein trafficking PGA2 Calc_CGRP_IAPP PF00214.19 RLN97524.1 - 0.0078 16.6 4.4 0.066 13.6 4.4 2.2 1 1 0 1 1 1 1 Calcitonin / CGRP / IAPP family Nuc_deoxyri_tr2 PF15891.5 RLN97524.1 - 0.034 14.5 0.3 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like UPF0242 PF06785.11 RLN97524.1 - 0.12 12.4 12.1 0.022 14.9 8.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF445 PF04286.12 RLN97524.1 - 0.18 11.6 3.4 0.23 11.2 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) MPS2 PF17060.5 RLN97524.1 - 0.4 9.9 7.7 0.68 9.1 7.7 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 Ctr PF04145.15 RLN97524.1 - 2.4 8.8 4.2 2.9 8.5 0.0 2.3 1 1 1 2 2 2 0 Ctr copper transporter family Pannexin_like PF12534.8 RLN97524.1 - 4.3 6.3 4.8 0.63 9.1 0.8 1.6 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 zf-CCHC PF00098.23 RLN97525.1 - 1.3e-15 56.7 37.0 0.00012 22.0 0.4 5.3 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_2 PF13696.6 RLN97525.1 - 0.0026 17.5 8.0 0.037 13.8 0.2 5.3 5 1 0 5 5 5 3 Zinc knuckle zf-CCHC_4 PF14392.6 RLN97525.1 - 0.0049 16.6 31.4 0.19 11.5 1.9 5.2 5 0 0 5 5 5 4 Zinc knuckle zf-C2H2_10 PF16588.5 RLN97525.1 - 2.5 7.9 10.7 0.83 9.4 0.7 2.6 2 0 0 2 2 2 0 C2H2 zinc-finger 2-Hacid_dh_C PF02826.19 RLN97527.1 - 0.0016 17.8 0.1 0.0021 17.5 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PA14 PF07691.12 RLN97528.1 - 0.012 15.4 0.6 0.1 12.4 0.0 2.4 2 0 0 2 2 2 0 PA14 domain FAM70 PF14967.6 RLN97528.1 - 0.086 12.3 3.8 0.13 11.7 3.8 1.2 1 0 0 1 1 1 0 FAM70 protein MSA-2c PF12238.8 RLN97528.1 - 0.82 9.6 8.1 1.3 9.0 8.1 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c PA14 PF07691.12 RLN97529.1 - 0.046 13.5 0.3 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 PA14 domain SSP160 PF06933.11 RLN97529.1 - 0.081 11.1 6.9 0.1 10.8 6.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SAPS PF04499.15 RLN97531.1 - 0.15 10.8 1.2 0.14 10.9 1.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PPP4R2 PF09184.11 RLN97531.1 - 3.5 7.1 12.9 4.9 6.6 12.9 1.2 1 0 0 1 1 1 0 PPP4R2 MCM PF00493.23 RLN97532.1 - 5.1e-74 248.1 0.0 8.3e-74 247.5 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RLN97532.1 - 2.5e-21 75.8 1.0 5.3e-21 74.8 1.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RLN97532.1 - 9.5e-14 51.6 1.8 2.9e-13 50.0 1.8 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 RLN97532.1 - 7.9e-08 31.9 0.1 0.00018 20.9 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RLN97532.1 - 3.8e-07 30.2 0.0 8.1e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 RLN97532.1 - 0.045 13.1 0.1 0.1 11.9 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 RLN97532.1 - 0.048 14.0 0.2 0.2 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Ssu72 PF04722.13 RLN97533.1 - 5e-55 186.0 0.0 5.5e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein SDF PF00375.18 RLN97534.1 - 6.7e-68 229.5 29.0 4.1e-67 226.9 29.0 1.8 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF1176 PF06674.11 RLN97534.1 - 0.24 10.8 0.1 0.37 10.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Wbp11 PF09429.10 RLN97535.1 - 6.3e-17 61.7 14.8 6.3e-17 61.7 14.8 2.2 3 0 0 3 3 3 1 WW domain binding protein 11 NpwBP PF12622.7 RLN97535.1 - 1.1e-10 42.1 8.9 1.1e-10 42.1 8.9 3.1 2 2 0 2 2 2 1 mRNA biogenesis factor NCA2 PF08637.10 RLN97535.1 - 0.35 10.0 2.4 0.56 9.3 2.4 1.2 1 0 0 1 1 1 0 ATP synthase regulation protein NCA2 Ank_2 PF12796.7 RLN97536.1 - 5.2e-22 78.2 0.4 1.9e-07 31.5 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN97536.1 - 1.5e-15 57.3 0.1 0.00045 20.7 0.0 5.5 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN97536.1 - 1.1e-14 53.1 1.1 0.00067 19.9 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 RLN97536.1 - 1.4e-10 41.1 4.8 0.24 11.9 0.0 5.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 RLN97536.1 - 2.8e-09 37.0 2.1 0.2 12.0 0.0 4.7 2 2 3 5 5 5 3 Ankyrin repeats (many copies) SCIMP PF15050.6 RLN97537.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 SCIMP protein F-box-like PF12937.7 RLN97538.1 - 6.1e-07 29.2 0.2 2.2e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RLN97538.1 - 7.9e-06 25.6 0.2 1.7e-05 24.6 0.2 1.6 1 0 0 1 1 1 1 F-box domain Kinesin PF00225.23 RLN97539.1 - 3.2e-70 236.7 0.0 5.5e-70 235.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DENN PF02141.21 RLN97539.1 - 1.9e-33 116.0 0.2 1.7e-30 106.4 0.9 2.5 1 1 0 2 2 2 2 DENN (AEX-3) domain WD40 PF00400.32 RLN97539.1 - 1.4e-25 89.1 15.0 0.00014 22.6 0.0 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Microtub_bd PF16796.5 RLN97539.1 - 3.4e-16 59.5 0.0 6.7e-15 55.3 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding uDENN PF03456.18 RLN97539.1 - 1.4e-12 48.2 2.7 5.6e-12 46.2 0.2 3.1 3 0 0 3 3 3 1 uDENN domain ANAPC4_WD40 PF12894.7 RLN97539.1 - 0.0052 17.1 0.0 1.2 9.5 0.0 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN97539.1 - 0.015 14.0 0.2 4.1 5.9 0.0 2.9 3 0 0 3 3 3 0 Nucleoporin Nup120/160 SPA PF08616.10 RLN97539.1 - 0.018 15.0 0.0 0.048 13.6 0.0 1.8 1 0 0 1 1 1 0 Stabilization of polarity axis EF-1_beta_acid PF10587.9 RLN97539.1 - 5.1 7.6 7.5 24 5.5 7.5 2.3 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Rsa3 PF14615.6 RLN97540.1 - 2.8e-15 55.6 0.5 5.5e-15 54.7 0.1 1.7 2 0 0 2 2 2 1 Ribosome-assembly protein 3 DUF2052 PF09747.9 RLN97540.1 - 0.006 16.7 3.5 0.0081 16.3 3.5 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) SIMPL PF04402.14 RLN97540.1 - 1.8 9.0 7.3 2.4 8.6 7.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF541) DOT1 PF08123.13 RLN97541.1 - 4.3e-07 29.7 0.0 8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Pkinase PF00069.25 RLN97542.1 - 3.4e-64 216.7 0.0 5.4e-64 216.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97542.1 - 8.8e-33 113.7 0.0 1.6e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN97542.1 - 3.8e-07 29.2 0.0 9.8e-07 27.9 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase PH PF00169.29 RLN97542.1 - 3e-06 27.7 0.0 9.9e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 PH domain EF-hand_1 PF00036.32 RLN97542.1 - 0.0011 18.3 0.5 0.0031 17.0 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 RLN97542.1 - 0.0046 17.4 0.1 0.023 15.1 0.1 2.3 2 0 0 2 2 1 1 EF-hand domain pair Kinase-like PF14531.6 RLN97542.1 - 0.0054 16.1 0.0 0.035 13.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 RLN97542.1 - 0.0066 15.8 0.2 0.013 14.8 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_6 PF13405.6 RLN97542.1 - 0.018 14.9 0.1 0.075 13.0 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain Caleosin PF05042.13 RLN97542.1 - 0.13 12.2 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 Caleosin related protein EF-hand_5 PF13202.6 RLN97542.1 - 0.15 11.6 0.0 0.44 10.1 0.0 1.7 1 0 0 1 1 1 0 EF hand SopA PF13981.6 RLN97542.1 - 0.16 12.4 0.0 0.38 11.2 0.0 1.6 1 0 0 1 1 1 0 SopA-like central domain Patatin PF01734.22 RLN97543.1 - 7.4e-25 88.3 0.1 1.7e-24 87.2 0.1 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase cNMP_binding PF00027.29 RLN97543.1 - 5.9e-21 74.3 0.6 4.6e-09 36.2 0.0 4.1 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain DUF2076 PF09849.9 RLN97543.1 - 0.14 12.1 0.4 0.3 11.1 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) NAGLU_C PF12972.7 RLN97543.1 - 0.2 11.2 0.8 0.38 10.2 0.8 1.3 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain AIRC PF00731.20 RLN97544.1 - 1.3e-05 24.8 2.0 0.00012 21.7 0.8 2.8 2 1 0 2 2 2 1 AIR carboxylase ThiF PF00899.21 RLN97545.1 - 2e-60 204.2 0.3 3.3e-60 203.5 0.3 1.3 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 RLN97545.1 - 5.5e-10 39.7 0.0 1e-09 38.8 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.20 RLN97545.1 - 0.0085 16.2 0.4 0.042 13.9 0.1 2.1 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 RLN97545.1 - 0.01 16.1 2.0 0.085 13.1 2.0 2.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PglD_N PF17836.1 RLN97545.1 - 0.043 14.4 0.0 0.14 12.8 0.0 1.9 2 0 0 2 2 2 0 PglD N-terminal domain DUF3138 PF11336.8 RLN97545.1 - 1.7 7.2 3.6 2.5 6.6 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SlyX PF04102.12 RLN97545.1 - 3.6 8.3 7.7 0.62 10.7 1.9 2.3 2 0 0 2 2 2 0 SlyX PHD PF00628.29 RLN97546.1 - 8.1e-08 32.0 7.2 1.5e-07 31.1 7.2 1.4 1 0 0 1 1 1 1 PHD-finger FANCL_C PF11793.8 RLN97546.1 - 0.017 15.3 1.7 0.036 14.3 1.7 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain ZF-HD_dimer PF04770.12 RLN97546.1 - 0.046 14.1 2.6 0.16 12.4 2.6 2.0 1 1 0 1 1 1 0 ZF-HD protein dimerisation region zf-PHD-like PF15446.6 RLN97546.1 - 0.097 12.3 1.4 0.26 10.9 1.4 1.7 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Cwf_Cwc_15 PF04889.12 RLN97546.1 - 0.59 9.8 17.9 1.4 8.6 3.3 2.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 RLN97546.1 - 0.68 9.2 29.2 0.14 11.5 5.0 2.4 3 0 0 3 3 3 0 BUD22 SnAC PF14619.6 RLN97546.1 - 1.9 9.2 10.2 0.53 10.9 0.3 3.9 2 2 1 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex RINGv PF12906.7 RLN97546.1 - 5.9 7.1 6.3 10 6.3 6.3 1.4 1 0 0 1 1 1 0 RING-variant domain Pkinase PF00069.25 RLN97547.1 - 4.1e-62 209.9 0.0 6.4e-62 209.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97547.1 - 2.8e-42 144.8 0.0 4.1e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase IFT57 PF10498.9 RLN97547.1 - 7.8e-30 104.1 0.0 1.6e-29 103.0 0.0 1.5 1 1 0 1 1 1 1 Intra-flagellar transport protein 57 Kinase-like PF14531.6 RLN97547.1 - 3.2e-07 30.0 0.1 2.4e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RLN97547.1 - 9.5e-05 21.3 0.6 0.00082 18.3 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 RLN97547.1 - 0.011 15.6 0.0 0.011 15.6 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN97547.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EVI2A PF05399.11 RLN97547.1 - 0.12 12.0 0.7 0.19 11.3 0.7 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) FTA2 PF13095.6 RLN97547.1 - 0.15 11.6 1.8 9.3 5.8 0.0 2.6 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 SRP-alpha_N PF04086.13 RLN97547.1 - 1 9.2 5.1 2 8.3 5.1 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal FGF-BP1 PF06473.12 RLN97547.1 - 2.2 8.0 4.4 3.5 7.4 4.4 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) zf-C2H2 PF00096.26 RLN97548.1 - 1e-18 66.6 27.4 2.8e-06 27.5 2.0 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN97548.1 - 1.2e-14 53.7 25.2 0.0029 18.3 0.5 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RLN97548.1 - 9e-14 51.2 27.3 1.5e-05 25.2 1.8 5.4 5 0 0 5 5 5 3 Zinc-finger double domain FOXP-CC PF16159.5 RLN97548.1 - 7.3e-06 26.5 8.1 0.0077 16.8 0.1 4.2 2 1 3 5 5 5 2 FOXP coiled-coil domain zf-TRAF PF02176.18 RLN97548.1 - 0.00058 20.5 9.7 0.14 12.9 1.3 2.4 1 1 1 2 2 2 2 TRAF-type zinc finger zf-C2H2_jaz PF12171.8 RLN97548.1 - 0.0013 19.0 4.4 4.8 7.6 0.0 4.3 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 RLN97548.1 - 0.0073 16.6 7.3 0.06 13.6 2.4 3.4 2 1 1 3 3 3 1 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 RLN97548.1 - 0.011 15.5 17.6 0.28 11.0 0.4 3.7 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 RLN97548.1 - 0.1 12.6 16.2 0.52 10.4 0.0 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf_ZIC PF18366.1 RLN97548.1 - 0.17 12.0 8.8 0.91 9.7 0.3 3.9 2 1 2 4 4 4 0 Zic proteins zinc finger domain zf-DNA_Pol PF08996.10 RLN97548.1 - 0.27 11.0 1.3 0.59 9.9 0.7 1.8 1 1 0 1 1 1 0 DNA Polymerase alpha zinc finger IBR PF01485.21 RLN97548.1 - 0.41 10.9 7.6 1.1 9.6 0.6 3.3 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain zf-C2H2_aberr PF17017.5 RLN97548.1 - 0.81 9.8 8.3 23 5.1 0.2 3.9 2 1 2 4 4 4 0 Aberrant zinc-finger IGPD PF00475.18 RLN97549.1 - 1.2e-59 200.8 1.1 2.4e-59 199.8 1.1 1.5 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase HAD_2 PF13419.6 RLN97549.1 - 1.2e-19 71.1 0.0 1.6e-18 67.5 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RLN97549.1 - 2.5e-11 44.3 0.0 3.4e-08 34.1 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RLN97549.1 - 3e-09 36.8 0.1 7.9e-09 35.5 0.1 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Elicitin PF00964.17 RLN97550.1 - 6.4e-22 77.5 4.2 1e-21 76.8 4.2 1.3 1 0 0 1 1 1 1 Elicitin OKR_DC_1 PF01276.20 RLN97550.1 - 0.0081 14.9 1.1 0.12 11.1 0.2 2.0 1 1 1 2 2 2 2 Orn/Lys/Arg decarboxylase, major domain Elicitin PF00964.17 RLN97551.1 - 1.2e-19 70.2 3.5 2.1e-19 69.4 3.5 1.4 1 0 0 1 1 1 1 Elicitin End_N_terminal PF12218.8 RLN97551.1 - 0.061 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase PorA PF11271.8 RLN97551.1 - 0.086 12.1 0.6 0.14 11.4 0.1 1.5 2 0 0 2 2 2 0 Porin PorA Sporozoite_P67 PF05642.11 RLN97551.1 - 0.98 7.4 7.3 0.27 9.3 5.1 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Spc7_N PF15402.6 RLN97551.1 - 5.2 5.2 9.2 6.6 4.8 9.2 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 zf-C2H2 PF00096.26 RLN97552.1 - 5.3e-18 64.4 24.9 3.4e-06 27.2 0.9 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN97552.1 - 3.7e-13 49.1 23.1 0.0021 18.7 0.6 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RLN97552.1 - 1.7e-09 37.7 26.7 1.8e-06 28.1 2.0 5.3 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_11 PF16622.5 RLN97552.1 - 3.2e-05 23.6 6.3 0.12 12.1 0.2 3.4 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 RLN97552.1 - 0.0026 18.0 7.1 0.14 12.5 1.1 2.9 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 RLN97552.1 - 0.0046 17.1 5.6 4.7 7.3 0.5 3.4 1 1 2 3 3 3 2 Aberrant zinc-finger FOXP-CC PF16159.5 RLN97552.1 - 0.029 15.0 7.8 2.5 8.8 0.0 4.0 1 1 3 4 4 4 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 RLN97552.1 - 0.082 12.9 0.5 0.082 12.9 0.5 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RLN97552.1 - 0.93 9.9 5.1 8.2 6.8 0.0 3.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 RLN97552.1 - 1.2 9.0 8.4 0.092 12.6 0.8 2.7 2 1 1 3 3 3 0 GAGA factor zf_ZIC PF18366.1 RLN97552.1 - 9.8 6.4 9.2 13 6.0 0.3 3.6 3 1 0 3 3 3 0 Zic proteins zinc finger domain zf-C2H2 PF00096.26 RLN97553.1 - 9.3e-21 73.1 18.6 7.2e-06 26.2 0.4 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RLN97553.1 - 7.1e-16 57.5 16.6 0.0014 19.3 0.9 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RLN97553.1 - 2e-12 46.9 21.1 3.2e-08 33.6 0.7 5.8 5 1 0 5 5 5 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 RLN97553.1 - 0.0001 22.2 7.3 0.41 10.7 0.1 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 RLN97553.1 - 0.00038 21.0 4.1 0.33 11.6 0.0 3.8 2 2 2 4 4 4 1 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 RLN97553.1 - 0.00043 20.5 6.0 0.13 12.6 3.1 3.3 1 1 1 3 3 3 1 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 RLN97553.1 - 0.00044 19.9 12.3 0.12 12.1 0.0 4.3 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 RLN97553.1 - 0.00048 19.8 11.7 0.057 13.2 0.7 3.7 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 RLN97553.1 - 0.0018 18.5 1.8 2 8.8 0.0 4.1 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 RLN97553.1 - 0.0054 16.9 6.6 1.1 9.3 0.9 3.5 1 1 3 4 4 4 2 Aberrant zinc-finger DUF4729 PF15866.5 RLN97553.1 - 0.045 13.1 4.1 1.9 7.8 0.1 3.2 2 2 2 4 4 4 0 Domain of unknown function (DUF4729) zf-C2H2_2 PF12756.7 RLN97553.1 - 0.099 13.0 6.6 3.6 8.0 1.3 3.2 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 RLN97553.1 - 0.26 11.3 0.1 0.26 11.3 0.1 3.2 3 1 1 4 4 4 0 BED zinc finger zf-met PF12874.7 RLN97553.1 - 0.34 11.4 4.5 24 5.5 0.0 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Ogr_Delta PF04606.12 RLN97553.1 - 0.57 10.2 7.8 19 5.4 0.3 3.6 3 1 1 4 4 4 0 Ogr/Delta-like zinc finger zf_ZIC PF18366.1 RLN97553.1 - 1.4 9.1 6.7 7.9 6.7 0.1 4.3 5 0 0 5 5 5 0 Zic proteins zinc finger domain zf-RRN7 PF11781.8 RLN97553.1 - 1.4 8.6 8.6 2.4 7.9 0.0 3.6 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Tegument_dsDNA PF12818.7 RLN97554.1 - 0.051 12.7 0.2 0.064 12.4 0.2 1.1 1 0 0 1 1 1 0 dsDNA viral tegument protein Mito_carr PF00153.27 RLN97556.1 - 1.3e-25 89.1 5.6 1.6e-10 40.7 0.2 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein C2 PF00168.30 RLN97557.1 - 6.6e-06 26.4 0.0 1.3e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain Exo_endo_phos PF03372.23 RLN97557.1 - 0.00095 18.7 0.0 0.0021 17.6 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Kinesin PF00225.23 RLN97558.1 - 1e-21 77.3 0.0 3.2e-17 62.5 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain C2 PF00168.30 RLN97558.1 - 0.061 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 C2 domain EELM2 PF15863.5 RLN97558.1 - 0.1 12.7 0.0 0.38 10.8 0.0 2.0 1 0 0 1 1 1 0 Extended EGL-27 and MTA1 homology domain Bep_C_terminal PF17841.1 RLN97558.1 - 0.36 11.1 8.2 2.3 8.5 0.6 2.8 2 0 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) COMP PF11598.8 RLN97558.1 - 3.5 8.2 6.5 26 5.4 0.3 4.7 5 0 0 5 5 5 0 Cartilage oligomeric matrix protein Aminotran_3 PF00202.21 RLN97559.1 - 1.8e-100 336.4 0.0 2.4e-100 336.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Kinesin PF00225.23 RLN97559.1 - 5e-07 29.0 0.0 7.6e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN97559.1 - 0.0082 16.1 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 1 Microtubule binding Dynein_C PF18199.1 RLN97560.1 - 3.4e-06 26.5 0.0 3.9e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain Peptidase_C1 PF00112.23 RLN97562.1 - 2.3e-74 250.2 1.6 3.1e-74 249.8 1.6 1.2 1 0 0 1 1 1 1 Papain family cysteine protease E1_DerP2_DerF2 PF02221.15 RLN97562.1 - 7.7e-14 52.3 0.0 1.3e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 ML domain Inhibitor_I29 PF08246.12 RLN97562.1 - 1.5e-08 35.0 0.4 3e-08 34.0 0.4 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 RLN97562.1 - 0.00069 18.5 2.9 0.042 12.6 0.1 2.5 3 0 0 3 3 3 2 Peptidase C1-like family Uteroglobin PF01099.17 RLN97562.1 - 0.2 12.0 0.1 1.1 9.6 0.0 2.2 2 0 0 2 2 2 0 Uteroglobin family B56 PF01603.20 RLN97563.1 - 2.9e-13 49.6 0.0 4.1e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Pkinase PF00069.25 RLN97564.1 - 7.6e-41 140.2 0.0 1e-40 139.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97564.1 - 7.2e-33 113.9 0.0 1.1e-32 113.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase hEGF PF12661.7 RLN97564.1 - 0.00081 19.9 129.6 0.015 15.9 7.9 12.7 12 0 0 12 12 12 7 Human growth factor-like EGF Haspin_kinase PF12330.8 RLN97564.1 - 0.001 18.1 0.0 0.0015 17.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain EGF PF00008.27 RLN97564.1 - 0.0047 17.2 31.1 0.0095 16.2 13.0 12.3 12 0 0 12 12 12 5 EGF-like domain APH PF01636.23 RLN97564.1 - 0.059 13.3 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 RLN97564.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN97564.1 - 0.17 10.6 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Acyl_transf_3 PF01757.22 RLN97567.1 - 2.5e-13 49.8 32.4 3.4e-13 49.4 32.4 1.2 1 0 0 1 1 1 1 Acyltransferase family CHS5_N PF16892.5 RLN97567.1 - 0.022 14.7 0.0 0.07 13.1 0.0 1.8 1 0 0 1 1 1 0 Chitin biosynthesis protein CHS5 N-terminus DSPc PF00782.20 RLN97568.1 - 2.7e-18 66.1 0.0 3e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RLN97568.1 - 0.0088 15.6 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase OST-HTH PF12872.7 RLN97568.1 - 0.17 11.7 0.0 5.7 6.8 0.0 2.1 2 0 0 2 2 2 0 OST-HTH/LOTUS domain Peptidase_M1 PF01433.20 RLN97570.1 - 7.5e-49 166.2 0.0 1e-48 165.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 RLN97570.1 - 1.9e-25 89.1 0.0 3.3e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 RLN97570.1 - 2e-21 77.0 0.0 8.2e-21 75.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain FYVE PF01363.21 RLN97571.1 - 1e-06 28.8 16.2 1e-06 28.8 16.2 2.0 2 1 0 2 2 2 1 FYVE zinc finger FAT PF02259.23 RLN97572.1 - 2e-78 264.1 0.0 3.4e-78 263.3 0.0 1.4 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 RLN97572.1 - 3e-73 246.7 0.1 4.8e-73 246.0 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 RLN97572.1 - 8.1e-46 155.9 1.4 3.5e-27 95.3 0.0 4.1 5 0 0 5 5 5 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 RLN97572.1 - 3.2e-43 146.2 0.4 3.2e-43 146.2 0.4 3.2 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain FATC PF02260.20 RLN97572.1 - 4e-18 64.9 0.7 1e-17 63.6 0.7 1.8 1 0 0 1 1 1 1 FATC domain IFRD PF05004.13 RLN97572.1 - 3.2e-06 26.5 11.9 0.0057 15.8 5.1 4.1 4 0 0 4 4 4 2 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 RLN97572.1 - 0.0076 16.6 22.5 0.67 10.4 0.0 8.0 8 0 0 8 8 7 2 HEAT repeats TPR_12 PF13424.6 RLN97572.1 - 0.019 15.3 1.0 12 6.2 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 RLN97572.1 - 0.034 14.2 0.4 12 6.2 0.3 4.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Cnd1 PF12717.7 RLN97572.1 - 0.078 13.0 2.8 8.4 6.4 0.4 3.3 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Sec7_N PF12783.7 RLN97572.1 - 0.087 12.7 2.6 0.27 11.1 0.2 3.2 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT PF02985.22 RLN97572.1 - 0.2 12.0 0.0 0.2 12.0 0.0 8.9 9 0 0 9 9 8 0 HEAT repeat CLASP_N PF12348.8 RLN97572.1 - 1.1 8.7 4.4 48 3.4 0.0 4.8 4 1 1 5 5 5 0 CLASP N terminal SAPS PF04499.15 RLN97573.1 - 0.054 12.3 3.4 0.052 12.3 3.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FAM70 PF14967.6 RLN97573.1 - 0.24 10.8 4.3 0.28 10.6 4.3 1.3 1 0 0 1 1 1 0 FAM70 protein Presenilin PF01080.17 RLN97573.1 - 5.2 5.7 10.8 6.9 5.3 10.8 1.1 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 RLN97574.1 - 4.9e-41 140.8 0.0 8.4e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97574.1 - 7.1e-41 140.2 0.0 1.2e-40 139.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN97574.1 - 0.001 18.5 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FSA_C PF10479.9 RLN97574.1 - 0.96 7.5 7.7 1.4 7.0 7.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus PPP4R2 PF09184.11 RLN97575.1 - 0.024 14.2 25.2 0.035 13.7 25.2 1.2 1 0 0 1 1 1 0 PPP4R2 CDC27 PF09507.10 RLN97575.1 - 0.065 12.6 21.2 0.079 12.3 21.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nucleo_P87 PF07267.11 RLN97575.1 - 4.5 6.0 18.0 5.6 5.7 18.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PPP4R2 PF09184.11 RLN97576.1 - 0.52 9.9 36.7 0.74 9.4 36.7 1.2 1 0 0 1 1 1 0 PPP4R2 CDC27 PF09507.10 RLN97576.1 - 1.9 7.8 28.4 2.6 7.3 28.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HEAT PF02985.22 RLN97578.1 - 1.4e-38 127.5 42.0 0.00054 20.0 0.0 24.6 25 0 0 25 25 25 9 HEAT repeat HEAT_2 PF13646.6 RLN97578.1 - 3.9e-20 72.0 83.1 0.00054 20.3 0.0 19.6 15 3 8 23 23 22 9 HEAT repeats CLASP_N PF12348.8 RLN97578.1 - 6.6e-16 58.6 0.6 6.9e-05 22.5 0.0 9.5 6 2 1 8 8 8 2 CLASP N terminal Cnd1 PF12717.7 RLN97578.1 - 6.5e-14 52.3 5.4 0.52 10.4 0.0 11.0 10 2 1 11 11 11 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 RLN97578.1 - 3e-13 49.9 97.9 0.00041 20.8 0.0 22.8 22 4 6 28 28 25 6 HEAT-like repeat Vac14_Fab1_bd PF12755.7 RLN97578.1 - 8.9e-11 42.2 0.0 1.8 9.2 0.0 8.9 9 2 2 11 11 9 2 Vacuolar 14 Fab1-binding region ParcG PF10274.9 RLN97578.1 - 3.7e-06 27.2 1.5 10 6.2 0.0 7.1 6 1 1 7 7 7 1 Parkin co-regulated protein NUC173 PF08161.12 RLN97578.1 - 0.00013 21.8 0.6 18 4.9 0.0 7.1 8 1 0 9 9 9 0 NUC173 domain RTP1_C1 PF10363.9 RLN97578.1 - 0.00034 20.8 6.7 1.6 9.0 0.6 6.3 6 0 0 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 RLN97578.1 - 0.00037 20.1 2.4 0.83 9.1 0.0 5.3 5 1 1 6 6 6 1 Tti2 family MMS19_C PF12460.8 RLN97578.1 - 0.0012 18.1 15.7 0.0026 17.0 3.9 6.2 6 2 0 7 7 7 1 RNAPII transcription regulator C-terminal Dopey_N PF04118.14 RLN97578.1 - 0.005 16.0 0.2 3.4 6.7 0.0 4.8 4 3 1 5 5 5 1 Dopey, N-terminal Ecm29 PF13001.7 RLN97578.1 - 0.0073 15.0 7.4 0.031 13.0 0.0 4.8 6 0 0 6 6 6 1 Proteasome stabiliser Caerin_1 PF07440.12 RLN97578.1 - 1.6 8.9 4.1 32 4.7 0.4 3.0 2 0 0 2 2 2 0 Caerin 1 protein RasGEF_N_2 PF14663.6 RLN97578.1 - 5.2 7.5 15.0 26 5.3 0.1 7.2 9 1 0 9 9 6 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm PF00514.23 RLN97578.1 - 9.9 6.4 13.6 29 4.9 0.1 6.7 8 0 0 8 8 5 0 Armadillo/beta-catenin-like repeat Pkinase PF00069.25 RLN97579.1 - 0.11 11.9 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain NADH_dhqG_C PF09326.11 RLN97579.1 - 0.14 12.9 0.0 0.33 11.7 0.0 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit G, C-terminal SF1-HH PF16275.5 RLN97580.1 - 5.9e-30 103.9 1.7 2e-29 102.2 1.7 1.9 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 RLN97580.1 - 1e-08 34.9 0.7 2.2e-08 33.8 0.7 1.6 1 0 0 1 1 1 1 KH domain DGF-1_C PF11040.8 RLN97580.1 - 0.06 13.3 0.1 0.52 10.4 0.0 2.6 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus zf-CCHC PF00098.23 RLN97580.1 - 0.1 12.7 11.8 0.062 13.4 4.9 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 RLN97580.1 - 0.93 9.4 12.4 0.077 12.8 6.9 2.1 2 0 0 2 2 2 0 Zinc knuckle PHD_4 PF16866.5 RLN97580.1 - 9.7 6.4 10.1 3.6e+02 1.3 10.1 2.6 1 1 0 1 1 1 0 PHD-finger DHDPS PF00701.22 RLN97581.1 - 5.7e-83 278.0 1.4 4.1e-82 275.1 1.4 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.6 RLN97581.1 - 0.014 14.9 0.1 0.021 14.3 0.1 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase SIS PF01380.22 RLN97581.1 - 0.053 13.4 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 SIS domain PA PF02225.22 RLN97581.1 - 0.084 12.9 0.7 0.68 10.0 0.2 2.4 2 0 0 2 2 2 0 PA domain Pribosyltran_N PF13793.6 RLN97581.1 - 0.088 12.8 0.0 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of ribose phosphate pyrophosphokinase Amidohydro_2 PF04909.14 RLN97581.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase Mad3_BUB1_I PF08311.12 RLN97582.1 - 7.7e-34 116.3 1.9 1.6e-32 112.1 1.8 2.5 1 1 0 1 1 1 1 Mad3/BUB1 homology region 1 DUF4614 PF15391.6 RLN97582.1 - 1.2 9.1 6.7 0.43 10.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) WW PF00397.26 RLN97583.1 - 2.7e-12 46.5 2.9 1.4e-09 37.9 0.7 2.1 2 0 0 2 2 2 2 WW domain YL1_C PF08265.11 RLN97583.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Trp_oprn_chp PF09534.10 RLN97584.1 - 0.15 11.8 1.8 0.21 11.4 0.3 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) LapA_dom PF06305.11 RLN97584.1 - 0.2 11.5 0.2 0.41 10.5 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4083 PF13314.6 RLN97584.1 - 0.25 11.3 0.2 0.61 10.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Peptidase_C1 PF00112.23 RLN97585.1 - 1.6e-43 149.3 9.3 4.2e-42 144.7 9.3 2.2 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RLN97585.1 - 6.4e-05 21.9 3.9 0.053 12.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Phage_holin_2_2 PF10746.9 RLN97585.1 - 0.22 11.2 0.9 2.5 7.8 1.7 2.3 2 1 0 2 2 2 0 Phage holin T7 family, holin superfamily II Phage_holin_2_1 PF04971.12 RLN97585.1 - 0.43 10.6 4.3 0.31 11.1 0.1 2.8 2 1 0 2 2 2 0 Bacteriophage P21 holin S adh_short PF00106.25 RLN97587.1 - 1.4e-26 93.1 0.1 1.9e-26 92.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN97587.1 - 7.4e-18 65.0 0.2 9.3e-18 64.6 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN97587.1 - 5.7e-09 36.1 0.2 7.7e-09 35.7 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN97587.1 - 1.3e-05 24.8 0.1 1.7e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 RLN97587.1 - 0.0043 16.4 0.1 0.0087 15.3 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S10 PF00450.22 RLN97588.1 - 5.8e-80 269.7 0.2 6.9e-80 269.5 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Ferritin-like PF12902.7 RLN97588.1 - 0.21 11.4 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 Ferritin-like adh_short PF00106.25 RLN97589.1 - 2.8e-32 111.8 0.1 1.8e-28 99.3 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN97589.1 - 7.9e-20 71.4 0.2 1.5e-19 70.5 0.1 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN97589.1 - 8.4e-10 38.9 0.0 1.3e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Pyr_redox_3 PF13738.6 RLN97589.1 - 7.9e-05 22.1 0.0 0.00011 21.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 RLN97589.1 - 0.0029 17.1 0.1 0.0036 16.8 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 RLN97589.1 - 0.033 14.1 0.1 0.052 13.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YchF-GTPase_C PF06071.13 RLN97590.1 - 9.1e-31 105.9 0.0 1.9e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 RLN97590.1 - 3.9e-20 72.0 0.0 1e-19 70.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RLN97590.1 - 1.2e-07 31.4 0.0 2.1e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 RLN97590.1 - 0.0052 15.8 0.0 0.0099 14.9 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 RLN97590.1 - 0.072 13.6 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 RLN97590.1 - 0.16 12.0 0.0 0.37 10.8 0.0 1.9 1 1 0 1 1 1 0 Dynamin family GTP_EFTU PF00009.27 RLN97590.1 - 0.2 11.2 0.9 0.76 9.3 0.0 2.2 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain MULE PF10551.9 RLN97591.1 - 0.052 14.0 0.1 0.096 13.1 0.1 1.5 1 0 0 1 1 1 0 MULE transposase domain AMP_N PF05195.16 RLN97593.1 - 0.18 11.6 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain Tub_N PF16322.5 RLN97594.1 - 0.05 14.0 6.5 0.085 13.3 6.5 1.4 1 0 0 1 1 1 0 Tubby N-terminal HypA PF01155.19 RLN97594.1 - 0.055 13.5 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TFIIE_alpha PF02002.17 RLN97594.1 - 0.058 13.2 0.2 0.15 11.9 0.2 1.7 1 0 0 1 1 1 0 TFIIE alpha subunit DUF4572 PF15139.6 RLN97595.1 - 0.0091 15.9 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4572) Arm PF00514.23 RLN97596.1 - 2.7e-13 49.4 47.8 0.023 14.8 0.1 17.9 20 0 0 20 20 20 3 Armadillo/beta-catenin-like repeat KAP PF05804.12 RLN97596.1 - 1.8e-08 33.0 1.7 0.12 10.5 0.1 4.6 4 1 1 5 5 5 3 Kinesin-associated protein (KAP) HEAT_2 PF13646.6 RLN97596.1 - 7.1e-08 32.7 25.0 0.00024 21.4 0.4 7.9 5 1 1 6 6 6 2 HEAT repeats RICTOR_V PF14668.6 RLN97596.1 - 3.5e-07 30.4 5.1 0.031 14.5 0.2 5.7 5 0 0 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_N PF03224.14 RLN97596.1 - 0.00024 20.5 0.6 0.26 10.5 0.1 4.9 4 2 0 4 4 4 1 V-ATPase subunit H HEAT_EZ PF13513.6 RLN97596.1 - 0.012 16.2 0.2 0.012 16.2 0.2 9.2 7 3 3 10 10 10 0 HEAT-like repeat PUL PF08324.11 RLN97596.1 - 0.013 14.8 15.9 0.063 12.5 0.1 5.3 3 1 1 5 5 5 0 PUL domain Adaptin_N PF01602.20 RLN97596.1 - 0.025 13.2 0.1 0.025 13.2 0.1 3.9 5 0 0 5 5 5 0 Adaptin N terminal region HEAT PF02985.22 RLN97596.1 - 0.19 12.1 28.3 2.4 8.6 0.2 9.7 9 0 0 9 9 9 0 HEAT repeat LRR_8 PF13855.6 RLN97597.1 - 6.1e-20 70.8 6.5 5.9e-12 45.2 1.9 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RLN97597.1 - 7e-15 54.9 5.3 1.4e-05 25.3 0.1 2.7 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN97597.1 - 3.9e-05 23.6 0.4 17 6.4 0.0 4.4 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_9 PF14580.6 RLN97597.1 - 0.00065 19.2 1.6 0.00093 18.7 1.6 1.2 1 0 0 1 1 1 1 Leucine-rich repeat Heme_oxygenase PF01126.20 RLN97599.1 - 2.2e-17 63.5 0.0 2.6e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Heme oxygenase TPR_17 PF13431.6 RLN97600.1 - 3.1e-07 30.3 3.4 0.0024 18.1 0.1 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN97600.1 - 6.2e-06 25.9 5.6 0.0036 17.3 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 RLN97600.1 - 6.4e-05 23.3 3.3 0.013 16.1 0.1 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 RLN97600.1 - 0.00012 21.7 2.8 0.68 9.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN97600.1 - 0.00015 21.9 2.7 0.00033 20.7 2.7 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN97600.1 - 0.00024 21.7 9.9 0.00093 19.8 4.5 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN97600.1 - 0.0036 17.8 6.4 0.0036 17.8 6.4 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN97600.1 - 0.0037 17.4 1.8 4.9 7.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Rax2 PF12768.7 RLN97600.1 - 0.0098 15.4 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity TPR_11 PF13414.6 RLN97600.1 - 0.013 15.1 6.7 0.15 11.7 0.4 3.4 2 1 1 3 3 3 0 TPR repeat TPR_14 PF13428.6 RLN97600.1 - 0.022 15.5 0.7 0.022 15.5 0.7 3.3 2 1 1 3 3 2 0 Tetratricopeptide repeat Cellulase PF00150.18 RLN97600.1 - 0.029 13.8 0.0 0.037 13.5 0.0 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) TPR_4 PF07721.14 RLN97600.1 - 0.036 14.7 11.8 1.8 9.4 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 RLN97600.1 - 3.1 8.0 5.2 13 6.0 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 RLN97600.1 - 3.4 8.0 9.3 2.7 8.3 4.3 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat Meiosis_expr PF15163.6 RLN97602.1 - 2.7e-28 98.4 4.4 3.6e-28 98.0 4.4 1.2 1 0 0 1 1 1 1 Meiosis-expressed PilX_N PF14341.6 RLN97602.1 - 0.26 11.3 2.0 0.38 10.7 2.0 1.2 1 0 0 1 1 1 0 PilX N-terminal Myb_DNA-binding PF00249.31 RLN97603.1 - 1.1e-32 111.9 4.0 3.1e-10 40.1 0.0 4.7 4 0 0 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN97603.1 - 2.6e-26 91.6 0.1 1.9e-08 34.4 0.0 4.8 2 1 3 5 5 5 4 Myb-like DNA-binding domain SLIDE PF09111.10 RLN97603.1 - 0.13 12.3 0.0 1.6 8.8 0.0 2.7 2 1 1 3 3 3 0 SLIDE SAC3_GANP PF03399.16 RLN97604.1 - 1.7e-58 198.4 0.6 1.9e-58 198.2 0.6 1.1 1 0 0 1 1 1 1 SAC3/GANP family Caskin-Pro-rich PF16907.5 RLN97604.1 - 0.00043 20.7 5.3 0.022 15.3 0.1 2.8 2 0 0 2 2 2 2 Proline rich region of Caskin proteins HTH_47 PF16221.5 RLN97605.1 - 0.043 13.4 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 winged helix-turn-helix MFMR_assoc PF16596.5 RLN97605.1 - 0.089 13.2 3.6 0.061 13.8 1.1 1.8 2 0 0 2 2 2 0 Disordered region downstream of MFMR DUF4611 PF15387.6 RLN97605.1 - 0.1 12.8 1.1 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) MFS_1 PF07690.16 RLN97607.1 - 7.9e-11 41.5 8.1 7.9e-11 41.5 8.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily PLDc_2 PF13091.6 RLN97608.1 - 6.4e-07 29.3 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.22 RLN97608.1 - 2.1e-05 24.5 0.0 5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Phospholipase D Active site motif TMEM144 PF07857.12 RLN97609.1 - 2.9e-43 148.1 0.6 1.5e-20 73.5 0.2 2.1 2 0 0 2 2 2 2 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 RLN97609.1 - 2.3e-05 23.9 0.4 2.3e-05 23.9 0.4 2.3 2 0 0 2 2 2 2 Sugar transport protein Vut_1 PF02592.15 RLN97609.1 - 0.1 12.9 0.1 0.1 12.9 0.1 2.1 3 0 0 3 3 3 0 Putative vitamin uptake transporter DMT_YdcZ PF04657.13 RLN97609.1 - 0.96 9.7 21.3 0.11 12.8 7.3 2.7 3 0 0 3 3 3 0 Putative inner membrane exporter, YdcZ EamA PF00892.20 RLN97609.1 - 2.6 8.2 14.4 0.073 13.2 4.0 3.0 3 0 0 3 3 3 0 EamA-like transporter family DUF1664 PF07889.12 RLN97610.1 - 0.39 10.8 21.6 0.028 14.5 2.9 5.0 1 1 3 5 5 5 0 Protein of unknown function (DUF1664) Ank_2 PF12796.7 RLN97611.1 - 6.4e-23 81.2 0.1 2.6e-12 47.2 0.0 3.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN97611.1 - 5e-13 49.0 2.3 0.082 13.3 0.0 5.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN97611.1 - 1e-12 48.3 8.7 2.2e-06 28.1 1.5 4.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN97611.1 - 2.5e-12 46.7 5.5 0.031 14.7 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 RLN97611.1 - 1.7e-11 43.3 2.2 0.46 11.2 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat PDZ_6 PF17820.1 RLN97611.1 - 1.1e-10 41.2 0.8 0.00023 20.9 1.5 3.0 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 RLN97611.1 - 2.1e-07 31.2 0.0 0.034 14.5 0.0 2.8 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 RLN97611.1 - 9.5e-06 25.9 0.3 0.032 14.6 0.1 3.3 3 0 0 3 3 3 2 PDZ domain Yae1_N PF09811.9 RLN97612.1 - 3.5e-07 29.8 1.7 3.5e-07 29.8 1.7 1.6 2 0 0 2 2 2 1 Essential protein Yae1, N terminal COX4_pro_2 PF07835.12 RLN97613.1 - 0.08 13.1 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV Aldedh PF00171.22 RLN97618.1 - 1.3e-175 584.4 0.0 1.4e-175 584.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 RLN97619.1 - 6.4e-171 568.9 0.1 7.2e-171 568.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AA_permease_2 PF13520.6 RLN97620.1 - 1.3e-38 132.9 39.8 1.8e-38 132.5 39.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN97620.1 - 9.3e-27 93.7 38.1 1.3e-26 93.2 38.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 RLN97621.1 - 1.1e-42 146.3 38.2 1.5e-42 146.0 38.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN97621.1 - 2.3e-28 99.0 37.6 3.8e-28 98.3 37.6 1.3 1 0 0 1 1 1 1 Amino acid permease DnaJ PF00226.31 RLN97623.1 - 7.7e-07 29.2 2.3 1.4e-06 28.3 2.3 1.5 1 0 0 1 1 1 1 DnaJ domain P5CR_dimer PF14748.6 RLN97623.1 - 0.04 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation Rap_GAP PF02145.15 RLN97625.1 - 3.6e-42 144.0 0.0 7.4e-42 143.0 0.0 1.5 2 0 0 2 2 2 1 Rap/ran-GAP DUF3384 PF11864.8 RLN97625.1 - 1.3e-26 93.6 0.0 2.3e-25 89.5 0.0 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3384) Tuberin PF03542.16 RLN97625.1 - 1e-06 28.1 0.0 0.00067 18.9 0.0 2.6 2 0 0 2 2 2 2 Tuberin Cu_amine_oxid PF01179.20 RLN97626.1 - 1.5e-149 498.4 0.0 1.8e-149 498.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 RLN97626.1 - 3.1e-15 56.4 0.0 6.1e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 RLN97626.1 - 0.00012 22.2 0.0 0.00026 21.1 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Ribosomal_S4e PF00900.20 RLN97626.1 - 0.2 11.6 0.0 0.5 10.3 0.0 1.6 1 0 0 1 1 1 0 Ribosomal family S4e Cupin_6 PF12852.7 RLN97627.1 - 0.045 13.5 0.0 0.084 12.6 0.0 1.6 1 1 0 1 1 1 0 Cupin IBR PF01485.21 RLN97628.1 - 0.37 11.0 4.5 0.57 10.4 1.4 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain FYVE PF01363.21 RLN97628.1 - 3.8 7.7 8.2 8.7 6.6 7.9 1.7 1 1 1 2 2 2 0 FYVE zinc finger TPR_12 PF13424.6 RLN97629.1 - 3.2e-18 65.8 10.1 0.00054 20.2 0.5 6.9 5 2 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 RLN97629.1 - 3.2e-17 61.5 7.5 0.0018 18.0 0.0 7.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 RLN97629.1 - 7.9e-16 56.8 18.2 0.0027 17.7 0.0 9.4 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 RLN97629.1 - 7.4e-12 44.4 6.1 0.043 13.9 0.0 8.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN97629.1 - 6.4e-10 39.4 25.2 0.017 15.6 0.0 8.0 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 RLN97629.1 - 6.9e-10 38.9 16.5 1.8 9.6 0.3 10.1 8 1 2 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN97629.1 - 7.2e-10 38.3 8.5 0.0069 16.5 0.0 8.3 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 RLN97629.1 - 4.1e-05 23.6 5.0 0.042 14.0 0.1 5.6 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN97629.1 - 4.1e-05 24.1 13.3 0.12 13.0 0.6 7.6 6 4 1 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN97629.1 - 4.4e-05 23.2 13.5 0.14 12.1 0.0 8.1 10 0 0 10 10 10 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN97629.1 - 4.5e-05 23.6 7.7 0.36 11.1 0.0 6.3 6 1 1 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 RLN97629.1 - 9.4e-05 22.7 10.0 2.4 9.0 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR PF01535.20 RLN97629.1 - 0.0042 17.3 7.4 34 5.0 0.0 6.3 6 0 0 6 6 6 0 PPR repeat TPR_11 PF13414.6 RLN97629.1 - 0.04 13.6 7.7 29 4.4 0.1 6.4 7 0 0 7 7 7 0 TPR repeat TPR_6 PF13174.6 RLN97629.1 - 0.22 12.2 12.8 55 4.7 0.5 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 RLN97630.1 - 7e-07 29.3 1.0 2.5e-06 27.5 1.0 1.9 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family CobT PF06213.12 RLN97631.1 - 0.26 10.7 26.6 0.29 10.5 26.6 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DARPP-32 PF05395.12 RLN97631.1 - 2.9 8.1 19.7 2.9 8.1 19.7 1.0 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 DNA_pol_phi PF04931.13 RLN97631.1 - 4.7 5.2 32.1 4.9 5.1 32.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 RLN97631.1 - 4.7 6.4 19.9 5.4 6.2 19.9 1.2 1 0 0 1 1 1 0 NOA36 protein RPN2_C PF18004.1 RLN97631.1 - 6.1 6.7 16.1 6.3 6.7 16.1 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RNA_pol_Rpc4 PF05132.14 RLN97631.1 - 9.7 6.6 11.3 11 6.5 11.3 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Pkinase PF00069.25 RLN97632.1 - 7.9e-63 212.3 0.0 1.3e-62 211.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97632.1 - 5.1e-27 94.8 0.0 7.9e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN97632.1 - 1.4e-07 31.1 0.0 3.5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN97632.1 - 0.0022 17.4 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 RLN97632.1 - 0.067 12.8 0.0 0.17 11.5 0.0 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 RLN97632.1 - 0.13 11.1 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain GPCR_chapero_1 PF11904.8 RLN97633.1 - 2.2e-16 60.2 0.0 2.6e-16 59.9 0.0 1.0 1 0 0 1 1 1 1 GPCR-chaperone LpxI_C PF06230.11 RLN97633.1 - 0.18 11.6 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 LpxI C-terminal domain INTS2 PF14750.6 RLN97635.1 - 6.6e-11 40.6 5.0 0.0014 16.3 0.0 3.9 3 1 0 3 3 3 3 Integrator complex subunit 2 ABC_membrane PF00664.23 RLN97636.1 - 4.2e-87 292.3 23.4 3.5e-48 164.6 10.0 3.1 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 RLN97636.1 - 5.5e-34 117.6 0.0 1.1e-33 116.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN97636.1 - 4e-06 26.4 0.0 1.6e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 RLN97636.1 - 0.002 18.1 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase ABC_ATPase PF09818.9 RLN97636.1 - 0.018 13.9 0.6 0.046 12.5 0.1 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_29 PF13555.6 RLN97636.1 - 0.031 14.0 0.0 0.086 12.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 RLN97636.1 - 0.061 13.6 0.2 0.46 10.8 0.2 2.2 1 1 0 1 1 1 0 AAA domain Glycophorin_A PF01102.18 RLN97636.1 - 0.11 12.8 1.8 0.75 10.1 0.1 2.7 2 0 0 2 2 2 0 Glycophorin A APS_kinase PF01583.20 RLN97636.1 - 0.14 12.1 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase EF-hand_5 PF13202.6 RLN97637.1 - 6.9e-05 22.2 1.3 0.00034 20.0 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 RLN97637.1 - 0.00051 19.4 0.1 0.01 15.4 0.0 2.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RLN97637.1 - 0.00093 18.9 0.6 0.071 13.1 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 RLN97637.1 - 0.0069 16.8 0.2 1 9.9 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain pair 5_3_exonuc PF01367.20 RLN97638.1 - 0.035 14.7 0.0 0.084 13.5 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold PGA2 PF07543.12 RLN97638.1 - 0.097 12.6 0.8 28 4.7 0.0 3.2 4 0 0 4 4 4 0 Protein trafficking PGA2 Ferlin_C PF16165.5 RLN97638.1 - 0.19 11.7 0.1 0.32 10.9 0.1 1.3 1 0 0 1 1 1 0 Ferlin C-terminus CP12 PF02672.15 RLN97638.1 - 6 7.7 0.0 6 7.7 0.0 4.0 4 1 1 5 5 5 0 CP12 domain DUF5522 PF17653.1 RLN97639.1 - 2.7e-19 68.8 5.9 5.9e-19 67.8 5.9 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5522) Peripla_BP_2 PF01497.18 RLN97639.1 - 1.4e-06 28.1 0.1 7.4e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 Periplasmic binding protein Diphthami_syn_2 PF01902.17 RLN97639.1 - 1.1e-05 25.0 0.0 3.7e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Diphthamide synthase KxDL PF10241.9 RLN97640.1 - 0.02 15.1 4.6 0.02 15.1 4.6 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein RGS_DHEX PF18148.1 RLN97640.1 - 0.045 13.9 0.8 0.076 13.1 0.8 1.4 1 0 0 1 1 1 0 Regulator of G-protein signalling DHEX domain Metal_resist PF13801.6 RLN97640.1 - 0.054 13.7 1.4 0.45 10.7 0.3 2.1 1 1 1 2 2 2 0 Heavy-metal resistance CorA PF01544.18 RLN97640.1 - 0.055 12.8 3.9 0.082 12.2 3.9 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein BRCC36_C PF18110.1 RLN97640.1 - 0.19 11.9 3.1 4.4 7.5 0.0 3.3 4 0 0 4 4 4 0 BRCC36 C-terminal helical domain DUF4715 PF15835.5 RLN97640.1 - 0.28 11.3 3.6 0.59 10.2 3.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4715) DUF1043 PF06295.12 RLN97640.1 - 0.35 10.9 5.3 0.13 12.3 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF1664 PF07889.12 RLN97640.1 - 0.57 10.2 3.6 0.85 9.7 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 RLN97640.1 - 1 9.5 11.0 4.1 7.4 8.7 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 RLN97640.1 - 1.6 8.5 9.1 0.099 12.5 4.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Spc7 PF08317.11 RLN97640.1 - 2.3 7.0 13.9 0.078 11.8 8.0 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 RLN97640.1 - 2.4 8.7 14.7 0.19 12.2 9.7 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region TMCO5 PF14992.6 RLN97640.1 - 3.2 7.3 11.3 0.57 9.7 5.3 2.0 2 0 0 2 2 2 0 TMCO5 family HAUS6_N PF14661.6 RLN97640.1 - 4 7.0 8.9 57 3.2 9.6 2.1 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus ABC_tran PF00005.27 RLN97641.1 - 1.1e-22 81.0 0.0 2.3e-16 60.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RLN97641.1 - 8.4e-08 31.9 0.3 1.5e-05 24.6 0.0 2.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 RLN97641.1 - 0.004 17.4 1.9 0.22 11.8 0.9 3.3 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 RLN97641.1 - 0.0064 15.3 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Predicted ATPase of the ABC class MoaE PF02391.17 RLN97641.1 - 0.013 15.8 0.5 5.6 7.3 0.1 2.7 3 0 0 3 3 3 0 MoaE protein RepB-RCR_reg PF10723.9 RLN97641.1 - 0.023 14.6 0.0 8.4 6.4 0.0 2.6 2 0 0 2 2 2 0 Replication regulatory protein RepB DUF592 PF04574.13 RLN97641.1 - 0.45 10.3 3.3 4 7.2 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF592) FmiP_Thoc5 PF09766.9 RLN97643.1 - 3.7e-65 220.6 0.0 1.4e-49 169.4 0.0 2.4 1 1 1 2 2 2 2 Fms-interacting protein/Thoc5 DUF3450 PF11932.8 RLN97643.1 - 0.19 11.0 5.0 0.033 13.5 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DASH_Dad2 PF08654.10 RLN97643.1 - 0.35 11.3 2.0 7.5 7.0 0.0 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad2 Spc7 PF08317.11 RLN97643.1 - 0.66 8.8 7.9 0.069 12.0 3.3 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein PTCB-BRCT PF12738.7 RLN97644.1 - 8.7e-25 86.5 0.7 4e-12 45.9 0.1 3.5 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.26 RLN97644.1 - 2.4e-20 72.7 0.0 5.2e-06 26.8 0.0 4.0 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 RLN97644.1 - 4.3e-14 52.7 0.0 2e-05 24.9 0.0 4.3 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 RLN97644.1 - 4.8e-13 49.0 0.6 0.00031 20.8 0.0 4.5 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 RLN97644.1 - 8e-08 32.5 0.0 0.0087 16.3 0.0 3.7 3 0 0 3 3 3 3 DNA ligase 3 BRCT domain Pkinase PF00069.25 RLN97645.1 - 3.6e-64 216.7 0.0 3.2e-63 213.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97645.1 - 3.4e-27 95.3 0.0 3.1e-21 75.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RLN97645.1 - 1.4e-10 41.0 0.0 0.0011 18.3 0.0 3.1 2 1 0 3 3 3 3 Kinase-like APH PF01636.23 RLN97645.1 - 0.00066 19.7 0.7 0.046 13.6 0.1 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 RLN97645.1 - 0.0017 17.8 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN97645.1 - 0.0024 16.7 0.0 0.0035 16.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Tubulin_C PF03953.17 RLN97648.1 - 2.7e-50 169.8 0.1 3.5e-50 169.4 0.1 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain SPX PF03105.19 RLN97651.1 - 0.012 15.5 1.1 0.018 15.0 1.1 1.2 1 0 0 1 1 1 0 SPX domain AAA PF00004.29 RLN97654.1 - 6.9e-34 117.1 0.0 1e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN97654.1 - 4.6e-06 27.1 0.1 4.4e-05 23.9 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 RLN97654.1 - 1.6e-05 24.7 0.0 3.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 RLN97654.1 - 8.2e-05 22.3 0.2 0.042 13.4 0.1 2.9 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 RLN97654.1 - 0.00015 22.0 0.1 0.036 14.4 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 RLN97654.1 - 0.0021 18.1 0.0 0.0086 16.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RLN97654.1 - 0.0026 17.9 0.0 0.0069 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 RLN97654.1 - 0.0048 16.3 0.1 0.022 14.2 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 RLN97654.1 - 0.0063 16.3 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 RLN97654.1 - 0.0067 15.7 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 RLN97654.1 - 0.0076 16.4 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 RLN97654.1 - 0.017 15.5 0.0 0.033 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 RLN97654.1 - 0.032 14.2 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_lid_3 PF17862.1 RLN97654.1 - 0.037 13.8 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA+ lid domain AAA_17 PF13207.6 RLN97654.1 - 0.043 14.3 0.0 0.084 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RLN97654.1 - 0.053 13.8 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RLN97654.1 - 0.061 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 RLN97654.1 - 0.063 13.2 0.1 0.4 10.6 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 RLN97654.1 - 0.066 13.8 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 RLN97654.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 RLN97654.1 - 0.14 11.3 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.26 RLN97654.1 - 0.17 11.6 0.0 1.1 8.9 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 RLN97654.1 - 0.17 11.6 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 RLN97654.1 - 0.19 11.6 0.0 0.29 11.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain Parvo_NS1 PF01057.17 RLN97654.1 - 0.25 10.4 0.0 0.53 9.3 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Arg_repressor PF01316.21 RLN97655.1 - 0.01 15.6 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain dDENN PF03455.19 RLN97655.1 - 0.076 13.0 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 dDENN domain WYL_3 PF18488.1 RLN97655.1 - 0.12 12.7 0.9 0.26 11.7 0.4 1.8 2 0 0 2 2 2 0 WYL domain DENN PF02141.21 RLN97655.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 DENN (AEX-3) domain CLZ PF16526.5 RLN97655.1 - 0.29 11.5 0.1 0.29 11.5 0.1 2.7 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SWI2_SNF2 PF18766.1 RLN97656.1 - 5e-21 75.4 0.3 4.8e-17 62.4 1.8 2.5 2 0 0 2 2 2 2 SWI2/SNF2 ATPase ResIII PF04851.15 RLN97656.1 - 3.2e-16 59.8 0.1 1.7e-15 57.4 0.1 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit WW PF00397.26 RLN97656.1 - 2.5e-11 43.4 0.3 4.9e-11 42.5 0.3 1.5 1 0 0 1 1 1 1 WW domain DEAD PF00270.29 RLN97656.1 - 1.3e-08 34.8 0.7 3.1e-08 33.6 0.7 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA PF00004.29 RLN97656.1 - 0.24 11.8 3.1 2.6 8.5 1.1 3.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN97656.1 - 0.55 10.5 3.0 2.2 8.5 0.9 3.0 2 1 0 2 2 2 0 AAA domain Thioredoxin PF00085.20 RLN97657.1 - 2.7e-29 101.2 1.0 2.5e-23 82.0 0.1 2.7 2 0 0 2 2 2 2 Thioredoxin Peptidase_C48 PF02902.19 RLN97657.1 - 2.3e-14 53.8 0.1 1.6e-06 28.2 0.0 2.2 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain TraF PF13728.6 RLN97657.1 - 0.0012 18.7 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 RLN97657.1 - 0.012 16.0 0.1 0.031 14.7 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RLN97657.1 - 0.016 15.5 0.0 0.25 11.7 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin-like OST3_OST6 PF04756.13 RLN97657.1 - 0.019 14.4 0.0 0.059 12.7 0.0 1.7 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 RLN97657.1 - 0.034 14.3 0.4 0.11 12.7 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin-like SEP PF08059.13 RLN97658.1 - 1.5e-22 80.0 0.0 5.4e-22 78.2 0.0 1.9 1 1 0 1 1 1 1 SEP domain UBX PF00789.20 RLN97658.1 - 9e-06 25.8 0.0 4.7e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 UBX domain Choline_transpo PF04515.12 RLN97659.1 - 5.7e-63 213.1 20.5 5.7e-63 213.1 20.5 2.0 1 1 1 2 2 2 1 Plasma-membrane choline transporter BRAP2 PF07576.12 RLN97660.1 - 9.2e-21 73.9 0.4 1.9e-20 72.9 0.4 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 RLN97660.1 - 1.2e-19 70.4 7.9 3e-19 69.1 7.9 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 RLN97660.1 - 7e-08 32.7 7.9 7e-08 32.7 7.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 RLN97660.1 - 2e-07 30.7 6.5 2e-07 30.7 6.5 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN97660.1 - 5.6e-05 22.8 3.5 5.6e-05 22.8 3.5 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 RLN97660.1 - 0.00027 20.8 16.2 0.0083 16.0 4.5 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RLN97660.1 - 0.0005 19.9 5.8 0.0005 19.9 5.8 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN97660.1 - 0.0044 17.0 1.9 0.0044 17.0 1.9 3.0 1 1 1 2 2 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 RLN97660.1 - 0.0046 17.2 8.4 0.0046 17.2 8.4 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 RLN97660.1 - 1.4 9.0 9.6 0.3 11.2 5.6 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 RLN97660.1 - 5.9 6.8 11.6 7.7 6.5 7.0 2.5 1 1 1 2 2 2 0 zf-RING of BARD1-type protein MGS PF02142.22 RLN97661.1 - 7.5e-16 58.1 0.0 9.6e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 MGS-like domain DUF4407 PF14362.6 RLN97662.1 - 0.43 9.9 5.0 0.42 9.9 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.12 RLN97662.1 - 0.43 9.0 2.7 0.48 8.9 2.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4446 PF14584.6 RLN97662.1 - 2.9 7.9 6.7 0.86 9.6 2.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) RuvC PF02075.17 RLN97663.1 - 0.02 14.7 0.0 0.044 13.7 0.0 1.6 1 1 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC DZF PF07528.14 RLN97663.1 - 0.036 13.7 0.0 0.089 12.4 0.0 1.7 1 0 0 1 1 1 0 DZF domain Myb_DNA-bind_4 PF13837.6 RLN97664.1 - 0.071 13.5 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 RLN97665.1 - 8.8e-10 38.4 0.0 0.034 13.5 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97665.1 - 0.0034 16.7 0.1 1.1 8.5 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase DUF936 PF06075.12 RLN97665.1 - 0.0089 15.0 1.8 0.018 14.0 1.8 1.4 1 0 0 1 1 1 1 Plant protein of unknown function (DUF936) Hint PF01079.20 RLN97666.1 - 2.5e-08 33.7 0.0 0.0002 20.9 0.0 2.3 2 0 0 2 2 2 2 Hint module Kelch_1 PF01344.25 RLN97666.1 - 1.7e-06 27.5 2.2 0.082 12.5 0.0 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 RLN97666.1 - 3.5e-05 23.7 1.2 1.7 8.7 0.0 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 RLN97666.1 - 0.028 14.7 6.5 2.5 8.5 0.3 3.6 4 0 0 4 4 4 0 Kelch motif PDZ_6 PF17820.1 RLN97668.1 - 9.3e-05 22.2 0.0 0.0039 17.0 0.1 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 RLN97668.1 - 0.0042 17.4 0.0 0.1 13.0 0.0 2.3 2 0 0 2 2 2 1 PDZ domain E2F_TDP PF02319.20 RLN97669.1 - 0.0078 16.2 0.0 0.021 14.9 0.0 1.8 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain LRR_6 PF13516.6 RLN97670.1 - 2.9e-20 70.5 9.3 2e-05 24.3 0.2 5.6 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.7 RLN97670.1 - 0.012 16.0 3.9 1.6 9.2 0.1 3.8 2 1 3 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN97670.1 - 0.23 11.2 3.0 3.7 7.4 1.0 3.1 2 1 1 3 3 3 0 Leucine rich repeat Myosin_head PF00063.21 RLN97671.1 - 2.1e-218 726.9 0.0 2.5e-218 726.6 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) CH PF00307.31 RLN97671.1 - 1.7e-14 53.9 0.1 4.5e-14 52.5 0.1 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 RLN97671.1 - 4.9e-05 23.5 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin IQ PF00612.27 RLN97671.1 - 0.0058 16.3 17.1 0.7 9.8 2.6 4.0 4 0 0 4 4 4 3 IQ calmodulin-binding motif AAA_16 PF13191.6 RLN97671.1 - 0.017 15.5 0.0 0.071 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 RLN97671.1 - 0.12 12.7 0.1 0.38 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Phage_Treg PF04761.12 RLN97671.1 - 0.15 12.2 0.1 1.3 9.1 0.0 2.6 3 0 0 3 3 3 0 Lactococcus bacteriophage putative transcription regulator GpcrRhopsn4 PF10192.9 RLN97672.1 - 5.7e-34 117.7 5.4 8.8e-34 117.1 5.4 1.2 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 RLN97672.1 - 0.00015 21.1 6.0 0.00023 20.5 6.0 1.3 1 0 0 1 1 1 1 Lung seven transmembrane receptor Pam17 PF08566.10 RLN97672.1 - 0.13 12.2 0.5 0.31 10.9 0.1 1.8 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 DUF3742 PF12553.8 RLN97672.1 - 0.23 11.6 1.3 0.74 9.9 1.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) DUSP PF06337.12 RLN97674.1 - 1.3e-08 35.3 0.0 8.9e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 DUSP domain F-box-like PF12937.7 RLN97674.1 - 0.0022 17.9 3.6 0.0075 16.1 0.3 3.2 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 RLN97674.1 - 0.0044 16.9 3.5 0.048 13.6 0.3 2.7 2 0 0 2 2 2 1 F-box domain Sensor PF13796.6 RLN97675.1 - 0.0095 16.0 4.5 0.74 9.8 0.2 3.2 3 0 0 3 3 3 2 Putative sensor DUF5123 PF17161.4 RLN97675.1 - 0.022 15.8 0.5 0.32 12.1 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5123) NosD PF05048.13 RLN97675.1 - 0.15 11.3 31.8 0.18 11.0 1.9 6.0 2 2 3 6 6 6 0 Periplasmic copper-binding protein (NosD) fn3 PF00041.21 RLN97677.1 - 6e-120 391.9 45.7 2.1e-11 44.0 0.9 24.9 25 0 0 25 25 25 18 Fibronectin type III domain Calx-beta PF03160.14 RLN97677.1 - 1.4e-34 118.2 3.7 7.4e-12 45.3 0.0 4.6 4 0 0 4 4 4 4 Calx-beta domain Pur_ac_phosph_N PF16656.5 RLN97677.1 - 3.3e-18 66.0 26.1 0.022 15.3 1.0 13.6 14 0 0 14 14 14 7 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 RLN97677.1 - 1.9e-05 24.9 0.0 0.76 10.1 0.0 7.2 9 0 0 9 9 9 1 Interferon-alpha/beta receptor, fibronectin type III SusE PF14292.6 RLN97677.1 - 5.2e-05 23.4 34.5 0.2 11.9 0.3 11.8 11 2 1 12 12 12 1 SusE outer membrane protein DUF4959 PF16323.5 RLN97677.1 - 0.00011 22.5 10.0 0.21 11.9 0.1 7.1 6 0 0 6 6 6 1 Domain of unknown function (DUF4959) Fimbrillin_C PF15495.6 RLN97677.1 - 0.022 15.2 1.4 11 6.6 0.0 5.0 7 0 0 7 7 7 0 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal PhoD_N PF16655.5 RLN97677.1 - 0.055 14.0 0.1 2.1 8.9 0.0 3.9 5 0 0 5 5 5 0 PhoD-like phosphatase, N-terminal domain Presenilin PF01080.17 RLN97678.1 - 0.014 14.2 2.1 0.029 13.2 1.5 1.6 2 0 0 2 2 2 0 Presenilin Acyltransferase PF01553.21 RLN97678.1 - 0.024 14.3 0.0 0.062 12.9 0.0 1.7 1 0 0 1 1 1 0 Acyltransferase DUF4131 PF13567.6 RLN97678.1 - 0.034 13.8 1.2 0.059 13.0 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Fig1 PF12351.8 RLN97678.1 - 5.8 6.8 7.3 0.25 11.3 1.6 1.5 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF155 PF02582.14 RLN97679.1 - 2.6e-27 96.0 0.5 4.7e-27 95.2 0.1 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 STN1_2 PF09170.10 RLN97679.1 - 0.04 14.1 0.1 0.51 10.5 0.0 2.3 2 0 0 2 2 2 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 GBP PF02263.19 RLN97680.1 - 3.7e-64 216.5 0.0 6.6e-64 215.7 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 RLN97680.1 - 3.4e-25 89.1 18.9 5e-25 88.5 18.9 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain MMR_HSR1 PF01926.23 RLN97680.1 - 0.12 12.5 0.0 0.43 10.7 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 RLN97680.1 - 0.23 11.5 1.4 0.73 9.9 0.0 2.3 2 0 0 2 2 2 0 Dynamin family SRP68 PF16969.5 RLN97681.1 - 9.7e-127 424.3 26.9 2e-126 423.2 26.9 1.5 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 DUF16 PF01519.16 RLN97681.1 - 1.1 9.8 3.6 8.8 6.9 0.4 2.8 2 1 0 2 2 2 0 Protein of unknown function DUF16 TPR_2 PF07719.17 RLN97681.1 - 2.3 8.5 7.9 3.6 7.9 1.2 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat RNase_PH PF01138.21 RLN97683.1 - 4.3e-33 114.6 0.1 7.3e-33 113.9 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RLN97683.1 - 8.9e-06 25.7 0.0 2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF1797 PF08796.10 RLN97683.1 - 0.26 11.4 0.5 0.72 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1797) Mannosyl_trans3 PF11051.8 RLN97684.1 - 0.00053 19.4 0.0 0.00071 19.0 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.8 RLN97685.1 - 3.6e-24 85.6 0.0 4.7e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Pkinase_Tyr PF07714.17 RLN97686.1 - 1.6e-55 188.2 0.0 5.8e-55 186.4 0.0 1.9 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.25 RLN97686.1 - 4.2e-38 131.2 0.0 2.3e-36 125.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain CTNNBL PF08216.11 RLN97686.1 - 0.063 13.5 0.2 1.2 9.4 0.0 2.8 3 0 0 3 3 3 0 Catenin-beta-like, Arm-motif containing nuclear Mannosyl_trans3 PF11051.8 RLN97687.1 - 2.1e-25 89.6 0.0 3.1e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative LisH_TPL PF17814.1 RLN97687.1 - 0.082 12.6 0.2 3 7.6 0.0 2.4 2 0 0 2 2 2 0 LisH-like dimerisation domain Glyco_tranf_2_4 PF13704.6 RLN97687.1 - 0.17 12.4 0.2 0.33 11.5 0.2 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Mannosyl_trans3 PF11051.8 RLN97688.1 - 4.8e-27 95.0 0.0 6.4e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative RdRP PF05183.12 RLN97691.1 - 2.5e-145 485.4 0.0 3.5e-145 485.0 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Helicase_C PF00271.31 RLN97691.1 - 2.7e-16 59.9 0.1 1e-15 58.0 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN97691.1 - 5e-12 46.1 0.0 1.2e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RLN97691.1 - 3.4e-10 40.0 0.0 9.1e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase NTP_transf_2 PF01909.23 RLN97691.1 - 0.012 15.8 0.1 0.11 12.8 0.0 2.6 2 0 0 2 2 2 0 Nucleotidyltransferase domain Polbeta PF18765.1 RLN97691.1 - 0.048 13.8 0.0 0.24 11.5 0.0 2.2 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Mitofilin PF09731.9 RLN97693.1 - 1.1e-51 176.5 12.0 1.2e-51 176.4 12.0 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Sld5 PF05916.11 RLN97693.1 - 0.12 12.8 3.6 0.28 11.7 3.6 1.5 1 0 0 1 1 1 0 GINS complex protein Exonuc_VII_L PF02601.15 RLN97693.1 - 0.15 11.6 7.7 0.2 11.2 7.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prominin PF05478.11 RLN97693.1 - 0.23 9.4 1.0 0.28 9.1 1.0 1.1 1 0 0 1 1 1 0 Prominin SOAR PF16533.5 RLN97693.1 - 0.23 11.5 5.8 0.58 10.2 5.8 1.7 1 0 0 1 1 1 0 STIM1 Orai1-activating region Med9 PF07544.13 RLN97693.1 - 0.29 11.3 5.8 2 8.6 2.9 3.0 3 2 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Lant_dehydr_C PF14028.6 RLN97693.1 - 0.57 9.7 9.6 0.55 9.7 6.0 1.9 1 1 1 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term DUF3646 PF12362.8 RLN97693.1 - 0.87 9.9 5.4 1.3 9.4 0.2 2.5 2 1 0 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal NAP PF00956.18 RLN97693.1 - 2.5 7.2 5.3 8.1 5.5 5.3 1.8 1 1 0 1 1 1 0 Nucleosome assembly protein (NAP) HIT PF01230.23 RLN97694.1 - 1.3e-14 54.7 0.4 2.8e-06 28.0 0.1 2.2 1 1 1 2 2 2 2 HIT domain DcpS_C PF11969.8 RLN97694.1 - 0.014 15.9 0.4 0.99 9.9 0.2 2.2 1 1 1 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding CBS PF00571.28 RLN97695.1 - 2.2e-14 53.6 0.1 1.1e-07 32.2 0.0 2.8 2 0 0 2 2 2 2 CBS domain DUF4272 PF14094.6 RLN97695.1 - 0.045 13.0 0.5 5.6 6.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4272) XRCC1_N PF01834.16 RLN97696.1 - 0.025 14.6 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 XRCC1 N terminal domain F5_F8_type_C PF00754.25 RLN97696.1 - 0.07 13.2 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 F5/8 type C domain SCAB-ABD PF16711.5 RLN97697.1 - 0.0018 18.1 0.7 0.0018 18.1 0.7 2.5 2 0 0 2 2 2 1 Actin-binding domain of plant-specific actin-binding protein LRR_4 PF12799.7 RLN97697.1 - 0.042 14.3 0.6 1.1 9.7 0.2 2.7 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RLN97697.1 - 0.06 13.4 0.2 8.2 6.8 0.2 3.2 3 0 0 3 3 3 0 Leucine Rich repeat DUF1192 PF06698.11 RLN97697.1 - 0.31 11.1 6.9 1 9.5 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) PGA2 PF07543.12 RLN97698.1 - 0.55 10.2 5.3 0.75 9.8 0.2 2.8 3 0 0 3 3 3 0 Protein trafficking PGA2 PBP1_TM PF14812.6 RLN97698.1 - 0.75 10.2 4.6 0.97 9.9 0.8 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MULE PF10551.9 RLN97699.1 - 0.0001 22.7 0.2 0.0034 17.8 0.0 2.9 2 0 0 2 2 2 1 MULE transposase domain SWIM PF04434.17 RLN97699.1 - 0.00051 19.7 0.2 0.0015 18.2 0.2 1.7 1 0 0 1 1 1 1 SWIM zinc finger DBD_Tnp_Mut PF03108.15 RLN97699.1 - 0.075 13.0 10.8 0.081 12.9 0.1 2.9 3 0 0 3 3 3 0 MuDR family transposase AFT PF08731.11 RLN97699.1 - 0.12 12.8 2.0 5.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Transcription factor AFT TFIID_20kDa PF03847.13 RLN97700.1 - 9.4e-20 70.9 0.0 1.6e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 RLN97700.1 - 0.045 13.8 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID-18kDa PF02269.16 RLN97700.1 - 0.18 11.8 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Tyr-DNA_phospho PF06087.12 RLN97701.1 - 8.9e-75 252.2 0.0 2.8e-41 141.8 0.0 2.0 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase Med8 PF10232.9 RLN97702.1 - 5.7e-08 32.6 6.0 2e-07 30.8 6.0 1.7 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Pro_CA PF00484.19 RLN97703.1 - 2e-44 151.6 0.1 2.9e-44 151.1 0.1 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Ras PF00071.22 RLN97704.1 - 1.3e-20 73.6 0.1 1.7e-20 73.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RLN97704.1 - 0.019 15.2 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Hydrolase_4 PF12146.8 RLN97705.1 - 1e-14 54.4 0.0 2.1e-14 53.4 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RLN97705.1 - 1.1e-09 38.3 0.0 8e-08 32.2 0.1 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 RLN97705.1 - 4e-08 33.2 0.0 1.3e-05 24.9 0.0 2.5 1 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 RLN97705.1 - 2.7e-05 23.9 0.0 4.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) AXE1 PF05448.12 RLN97705.1 - 8.2e-05 21.4 0.0 0.018 13.7 0.0 2.7 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Armet PF10208.9 RLN97705.1 - 0.0041 17.0 0.1 0.0076 16.2 0.1 1.4 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding Abhydrolase_6 PF12697.7 RLN97705.1 - 0.0046 17.6 0.0 0.0071 17.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 RLN97705.1 - 0.087 12.4 0.2 22 4.5 0.0 3.1 3 1 0 3 3 3 0 Dienelactone hydrolase family Asp2 PF16929.5 RLN97705.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter IMUP PF15761.5 RLN97706.1 - 0.22 12.2 5.0 0.37 11.5 5.0 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein tRNA-synt_2b PF00587.25 RLN97707.1 - 1.3e-35 123.0 0.0 1.9e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 RLN97707.1 - 4.1e-18 65.3 0.5 7e-18 64.6 0.5 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 RLN97707.1 - 0.0004 20.4 0.0 0.00083 19.4 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain eIF2A PF08662.11 RLN97710.1 - 5.7e-70 235.1 0.0 4.3e-68 229.0 0.0 2.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 RLN97710.1 - 0.0038 18.0 0.9 43 5.2 0.0 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat PD40 PF07676.12 RLN97710.1 - 0.25 11.4 3.9 5.4 7.1 0.1 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat CPSase_L_D2 PF02786.17 RLN97711.1 - 2.3e-73 246.2 0.0 3.5e-73 245.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 RLN97711.1 - 8.9e-39 132.5 0.2 8.9e-38 129.2 0.0 2.6 3 0 0 3 3 3 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 RLN97711.1 - 2.7e-30 104.6 0.0 5.3e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 RLN97711.1 - 8e-10 38.6 0.0 1.6e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HMGL-like PF00682.19 RLN97711.1 - 5.4e-07 29.4 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 HMGL-like ATP-grasp PF02222.22 RLN97711.1 - 2.9e-06 27.0 0.1 1.8e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 RLN97711.1 - 3.5e-05 23.9 0.0 6.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 RLN97711.1 - 0.0036 16.9 0.0 0.0073 15.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Ntox43 PF15537.6 RLN97711.1 - 0.052 13.6 0.0 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial toxin 43 ATPgrasp_Ter PF15632.6 RLN97711.1 - 0.061 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATPgrasp_ST PF14397.6 RLN97711.1 - 0.075 12.3 0.0 0.29 10.4 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ECH_1 PF00378.20 RLN97712.1 - 7.2e-36 123.8 0.0 8.9e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RLN97712.1 - 5.2e-21 75.5 0.0 1.8e-20 73.8 0.0 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SurA_N_3 PF13624.6 RLN97713.1 - 0.016 15.0 4.9 0.047 13.5 4.9 1.7 1 0 0 1 1 1 0 SurA N-terminal domain Lectin_N PF03954.14 RLN97713.1 - 0.21 11.3 8.7 0.12 12.1 3.9 2.6 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain DUF5082 PF16888.5 RLN97713.1 - 0.22 11.8 15.5 0.6 10.4 0.6 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) V_ATPase_I PF01496.19 RLN97713.1 - 0.22 9.4 10.1 0.32 8.9 10.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMCO5 PF14992.6 RLN97713.1 - 0.3 10.6 20.7 9.6 5.7 21.8 2.2 1 1 1 2 2 2 0 TMCO5 family Fib_alpha PF08702.10 RLN97713.1 - 0.53 10.5 11.4 0.16 12.1 2.2 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Peptidase_S46 PF10459.9 RLN97713.1 - 5.4 5.5 13.1 7.1 5.1 13.1 1.1 1 0 0 1 1 1 0 Peptidase S46 Ctf8 PF09696.10 RLN97714.1 - 3.3e-13 50.2 0.0 1.9e-12 47.7 0.0 2.0 1 1 0 1 1 1 1 Ctf8 zf-BED PF02892.15 RLN97715.1 - 9.6e-05 22.3 0.2 0.00021 21.3 0.2 1.6 1 0 0 1 1 1 1 BED zinc finger AMP-binding PF00501.28 RLN97716.1 - 5.7e-18 64.7 0.0 7.3e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme CcmE PF03100.15 RLN97717.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 2 0 0 2 2 2 0 CcmE NPCBM PF08305.11 RLN97718.1 - 4.6e-22 78.7 0.0 2.7e-21 76.2 0.0 2.2 2 0 0 2 2 2 1 NPCBM/NEW2 domain SPRY PF00622.28 RLN97718.1 - 3.2e-13 49.8 0.1 2.2e-09 37.5 0.0 2.5 2 0 0 2 2 2 2 SPRY domain Laminin_G_3 PF13385.6 RLN97718.1 - 4.4e-13 49.6 0.0 6.3e-12 45.9 0.0 2.6 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily zf-RanBP PF00641.18 RLN97718.1 - 0.003 16.8 4.5 0.0069 15.7 4.5 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others F5_F8_type_C PF00754.25 RLN97718.1 - 0.0065 16.6 0.1 0.026 14.7 0.1 2.0 2 0 0 2 2 2 1 F5/8 type C domain NADH_4Fe-4S PF10589.9 RLN97718.1 - 0.13 12.3 2.1 0.32 11.1 0.8 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Mrr_cat PF04471.12 RLN97719.1 - 1.8e-08 34.4 0.0 2.6e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease DUF2034 PF10356.9 RLN97719.1 - 6.3e-06 25.7 0.0 1.2e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) PP2C PF00481.21 RLN97719.1 - 4.8e-05 23.1 0.0 6.1e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 RLN97720.1 - 2e-54 185.0 0.1 2.3e-54 184.8 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RLN97720.1 - 0.0003 20.5 0.2 0.00067 19.4 0.2 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 RLN97720.1 - 0.00049 20.1 0.1 0.78 9.6 0.0 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) LON_substr_bdg PF02190.16 RLN97721.1 - 6.7e-09 35.9 0.1 8.2e-06 25.8 0.0 2.7 2 1 0 2 2 2 2 ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 PF03226.14 RLN97721.1 - 9.1e-05 22.6 0.0 0.00014 22.0 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF5039 PF16442.5 RLN97721.1 - 0.067 12.7 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) cNMP_binding PF00027.29 RLN97724.1 - 6.9e-22 77.3 0.0 2.3e-14 53.2 0.0 3.6 3 1 0 3 3 3 2 Cyclic nucleotide-binding domain RGS PF00615.19 RLN97724.1 - 5.5e-21 75.0 0.7 1.1e-20 74.1 0.7 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF3452 PF11934.8 RLN97725.1 - 0.08 12.5 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Nop53 PF07767.11 RLN97725.1 - 3.8 6.8 29.6 4.8 6.5 29.6 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 RLN97725.1 - 5.3 5.2 17.8 5.9 5.0 17.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Rgp1 PF08737.10 RLN97725.1 - 8.6 5.4 12.7 9.5 5.3 12.7 1.0 1 0 0 1 1 1 0 Rgp1 Vfa1 PF08432.10 RLN97725.1 - 9.3 6.5 18.0 13 6.1 18.0 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NDK PF00334.19 RLN97726.1 - 1.4e-51 174.1 0.0 1.9e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PsbQ PF05757.11 RLN97726.1 - 0.41 10.4 5.2 0.59 9.8 5.2 1.3 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Peptidase_C92 PF05708.12 RLN97727.1 - 0.00071 19.7 0.0 0.00095 19.3 0.0 1.3 1 0 0 1 1 1 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family BT1 PF03092.16 RLN97728.1 - 6.3e-17 61.0 11.2 9.9e-13 47.1 0.8 3.2 3 0 0 3 3 3 3 BT1 family PUCC PF03209.15 RLN97728.1 - 0.00025 20.2 0.2 0.00025 20.2 0.2 2.4 3 0 0 3 3 3 1 PUCC protein Proteasome PF00227.26 RLN97729.1 - 1e-50 171.9 0.2 1.2e-50 171.6 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RLN97729.1 - 1.7e-12 46.7 0.0 3.1e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature zf-CCHC_2 PF13696.6 RLN97729.1 - 0.081 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle OTU PF02338.19 RLN97730.1 - 3.1e-16 60.0 0.0 6.6e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Ank_4 PF13637.6 RLN97730.1 - 1.4e-07 31.9 0.1 3.1e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN97730.1 - 0.00031 21.0 0.2 0.018 15.4 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN97730.1 - 0.00083 19.9 0.1 0.0019 18.8 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN97730.1 - 0.0011 19.3 0.1 0.21 12.3 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat MBT PF02820.18 RLN97730.1 - 0.0091 16.3 0.0 0.24 11.8 0.0 2.3 2 0 0 2 2 2 1 mbt repeat UIM PF02809.20 RLN97730.1 - 0.013 15.3 21.7 1.3 9.1 2.9 4.6 4 0 0 4 4 4 0 Ubiquitin interaction motif Ank PF00023.30 RLN97730.1 - 0.02 15.3 0.3 0.54 10.8 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat Peptidase_C65 PF10275.9 RLN97730.1 - 0.024 14.1 0.8 3.1 7.2 0.0 2.7 3 0 0 3 3 3 0 Peptidase C65 Otubain Pkinase PF00069.25 RLN97731.1 - 1.2e-43 149.4 0.0 6.4e-40 137.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97731.1 - 6.1e-41 140.4 0.0 7.4e-39 133.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN97731.1 - 0.058 12.2 0.0 0.12 11.1 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase DUF4083 PF13314.6 RLN97732.1 - 0.12 12.4 0.1 0.21 11.6 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4083) rRNA_methylase PF06962.12 RLN97732.1 - 0.16 11.9 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative rRNA methylase ZT_dimer PF16916.5 RLN97733.1 - 1.8e-10 40.8 1.4 3.4e-10 39.9 1.4 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Cation_efflux PF01545.21 RLN97733.1 - 1.5e-05 24.8 0.4 2e-05 24.4 0.4 1.2 1 0 0 1 1 1 1 Cation efflux family Ank_4 PF13637.6 RLN97734.1 - 7.9e-15 55.0 0.7 0.00061 20.3 0.0 4.2 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN97734.1 - 3.1e-13 50.1 0.3 0.00025 21.6 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 RLN97734.1 - 5.2e-13 48.8 0.6 0.033 14.7 0.0 5.0 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 RLN97734.1 - 4.7e-12 45.9 2.7 3e-05 24.2 0.0 5.1 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN97734.1 - 1.5e-11 43.5 2.8 1.2 9.9 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat SPG48 PF14764.6 RLN97734.1 - 0.045 14.2 1.8 0.36 11.3 0.5 2.5 1 1 1 2 2 2 0 AP-5 complex subunit, vesicle trafficking MFS_1 PF07690.16 RLN97735.1 - 5e-12 45.4 47.3 1.7e-06 27.2 15.8 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RLN97735.1 - 9.5e-12 44.2 15.2 9.5e-12 44.2 15.2 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein COX6A PF02046.15 RLN97737.1 - 3.7e-06 27.4 0.0 4.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa NDUF_B12 PF08122.12 RLN97737.1 - 0.054 13.5 0.3 0.077 13.0 0.3 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family Lipase_3 PF01764.25 RLN97738.1 - 2.7e-26 92.1 0.0 1.1e-25 90.1 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) Ank_5 PF13857.6 RLN97738.1 - 4.2e-07 30.1 0.0 3.5e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN97738.1 - 4.3e-07 30.3 0.0 0.00059 20.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN97738.1 - 3.2e-06 27.6 0.0 8.8e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Hydrolase_4 PF12146.8 RLN97738.1 - 8.2e-05 22.0 0.0 0.00013 21.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 RLN97738.1 - 0.00019 21.1 0.0 0.00029 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Ank_3 PF13606.6 RLN97738.1 - 0.0002 21.5 0.0 0.011 16.2 0.0 3.3 4 0 0 4 4 3 1 Ankyrin repeat Ank PF00023.30 RLN97738.1 - 0.00038 20.8 0.0 0.0074 16.7 0.0 3.0 3 1 0 3 3 3 1 Ankyrin repeat Abhydrolase_6 PF12697.7 RLN97738.1 - 0.0013 19.3 0.1 0.0027 18.3 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 RLN97738.1 - 0.014 15.0 0.0 0.023 14.4 0.0 1.5 1 1 0 1 1 1 0 Putative esterase PGAP1 PF07819.13 RLN97738.1 - 0.031 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.12 RLN97738.1 - 0.031 13.8 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 RLN97738.1 - 0.073 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold MULE PF10551.9 RLN97741.1 - 2.5e-12 47.0 0.1 7e-12 45.6 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 RLN97741.1 - 0.021 15.5 0.1 0.051 14.3 0.1 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain DUF35_N PF12172.8 RLN97745.1 - 0.018 14.9 1.6 0.018 14.9 1.6 2.4 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Pkinase PF00069.25 RLN97746.1 - 9.9e-51 172.6 0.0 1.5e-50 172.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97746.1 - 9.3e-37 126.7 0.0 1.5e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 RLN97746.1 - 0.0011 19.1 0.1 0.0026 17.9 0.1 1.6 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 RLN97746.1 - 0.006 15.4 0.0 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 RLN97746.1 - 0.062 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF1640 PF07798.11 RLN97746.1 - 0.098 12.7 1.0 0.26 11.3 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) FAM76 PF16046.5 RLN97746.1 - 0.13 11.6 0.9 0.23 10.8 0.9 1.4 1 0 0 1 1 1 0 FAM76 protein NAPRTase_N PF17767.1 RLN97748.1 - 2.8e-31 108.5 0.0 4.3e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase PF04095.16 RLN97748.1 - 0.0078 15.8 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF3234 PF11572.8 RLN97748.1 - 0.14 12.4 0.0 0.6 10.3 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3234) LRR_4 PF12799.7 RLN97749.1 - 1.3e-46 155.7 33.4 1.4e-09 38.0 2.3 6.3 1 1 9 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN97749.1 - 3.8e-27 93.8 18.2 1.3e-06 28.1 0.0 5.5 2 1 1 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 RLN97749.1 - 6.7e-23 81.1 6.3 2.7e-09 36.8 0.0 3.5 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 RLN97749.1 - 7.5e-10 38.0 9.3 3.7 8.5 0.3 8.0 8 2 0 8 8 8 4 Leucine Rich Repeat LRR_6 PF13516.6 RLN97749.1 - 0.0017 18.2 17.8 2 8.7 0.1 7.5 10 0 0 10 10 10 2 Leucine Rich repeat Glyco_hydro_38N PF01074.22 RLN97751.1 - 9.8e-43 146.6 0.3 1.5e-42 145.9 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 RLN97751.1 - 1.6e-36 126.4 0.1 3.1e-36 125.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 RLN97751.1 - 2.8e-21 75.5 0.0 9e-21 73.8 0.0 2.0 1 0 0 1 1 1 1 Alpha mannosidase middle domain Sorb PF02208.16 RLN97751.1 - 0.046 13.6 0.4 0.14 12.1 0.4 1.8 1 0 0 1 1 1 0 Sorbin homologous domain Elf4 PF07011.11 RLN97751.1 - 0.052 13.5 3.0 0.18 11.7 0.1 2.8 3 0 0 3 3 3 0 Early Flowering 4 domain DPPIV_N PF00930.21 RLN97752.1 - 5.7e-71 239.1 0.0 1.7e-69 234.2 0.0 2.7 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 RLN97752.1 - 6.2e-50 169.6 0.0 1.5e-49 168.3 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 RLN97752.1 - 2.3e-10 40.5 1.0 2.8e-09 37.0 0.7 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PD40 PF07676.12 RLN97752.1 - 5e-06 26.3 1.0 0.099 12.6 0.0 3.9 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Hydrolase_4 PF12146.8 RLN97752.1 - 0.0075 15.6 0.5 0.047 12.9 0.1 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 RLN97752.1 - 0.018 14.6 0.0 0.12 11.9 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Esterase PF00756.20 RLN97752.1 - 0.096 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Proteasome_A_N PF10584.9 RLN97752.1 - 0.14 11.9 0.4 14 5.4 0.0 2.6 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Abhydrolase_2 PF02230.16 RLN97752.1 - 0.25 11.1 0.9 16 5.2 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase PAP_central PF04928.17 RLN97753.1 - 0.031 13.3 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain DUF4666 PF15697.5 RLN97753.1 - 0.09 13.5 0.1 0.21 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) Questin_oxidase PF14027.6 RLN97753.1 - 0.15 11.5 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Questin oxidase-like NUDIX PF00293.28 RLN97754.1 - 9.8e-08 32.1 1.2 2.8e-06 27.4 0.3 2.3 1 1 1 2 2 2 2 NUDIX domain Pkinase PF00069.25 RLN97755.1 - 4.7e-65 219.6 0.0 7.8e-64 215.6 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97755.1 - 1.8e-31 109.3 0.0 5.3e-29 101.3 0.0 3.2 2 1 0 2 2 2 1 Protein tyrosine kinase SnoaL_2 PF12680.7 RLN97755.1 - 6.6e-09 36.3 0.1 2.5e-08 34.5 0.1 2.0 1 0 0 1 1 1 1 SnoaL-like domain PH PF00169.29 RLN97755.1 - 7.4e-05 23.2 0.0 0.00016 22.2 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF4440 PF14534.6 RLN97755.1 - 0.021 15.2 0.0 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) Haspin_kinase PF12330.8 RLN97755.1 - 0.13 11.2 0.1 0.22 10.5 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 RLN97755.1 - 0.16 11.3 0.0 11 5.2 0.0 2.8 3 0 0 3 3 3 0 Kinase-like Macoilin PF09726.9 RLN97756.1 - 6.6 5.2 13.8 8.4 4.8 13.8 1.2 1 0 0 1 1 1 0 Macoilin family PAPA-1 PF04795.12 RLN97757.1 - 1.8 9.4 7.1 0.18 12.6 2.1 1.9 2 0 0 2 2 2 0 PAPA-1-like conserved region UCH PF00443.29 RLN97758.1 - 1.1e-72 244.7 0.0 1.3e-72 244.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 RLN97758.1 - 2.3e-19 69.8 0.0 5.5e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 RLN97758.1 - 5.4e-13 49.2 0.0 4e-07 29.9 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-MYND PF01753.18 RLN97758.1 - 1.8e-09 37.5 11.9 1.8e-09 37.5 11.9 3.1 3 0 0 3 3 3 1 MYND finger zf-AN1 PF01428.16 RLN97760.1 - 2.1e-09 37.4 7.6 3.8e-09 36.6 7.6 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Tax PF02959.16 RLN97760.1 - 0.028 13.9 0.1 0.04 13.4 0.1 1.2 1 0 0 1 1 1 0 HTLV Tax 4HBT_2 PF13279.6 RLN97761.1 - 7.6e-21 74.9 0.0 1e-20 74.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 RLN97761.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase superfamily 4HBT_2 PF13279.6 RLN97762.1 - 6.7e-16 58.9 0.0 1e-15 58.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Lon_C PF05362.13 RLN97763.1 - 2e-69 233.3 0.1 2.1e-42 145.0 0.2 2.4 1 1 1 2 2 2 2 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 RLN97763.1 - 1.5e-36 126.3 0.0 3.5e-36 125.1 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 RLN97763.1 - 1.6e-21 77.1 0.0 6.1e-21 75.2 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 RLN97763.1 - 2.2e-06 27.9 0.0 6.9e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 RLN97763.1 - 1e-05 25.6 0.0 2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 RLN97763.1 - 1.2e-05 24.5 0.0 2.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 RLN97763.1 - 7.9e-05 22.4 0.0 0.00047 19.9 0.0 2.4 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ChlI PF13541.6 RLN97763.1 - 0.00015 21.6 0.0 0.00034 20.4 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 RLN97763.1 - 0.0005 20.3 0.0 0.016 15.5 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RLN97763.1 - 0.00062 20.2 0.3 0.0043 17.4 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 RLN97763.1 - 0.011 15.7 0.0 0.039 13.8 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 RLN97763.1 - 0.015 15.8 0.0 0.063 13.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 RLN97763.1 - 0.025 14.6 0.0 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 RLN97763.1 - 0.027 14.6 0.1 0.14 12.2 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase NB-ARC PF00931.22 RLN97763.1 - 0.035 13.3 0.9 0.097 11.8 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 RLN97763.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 RLN97763.1 - 0.082 13.3 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase 4HBT_2 PF13279.6 RLN97764.1 - 2.1e-21 76.7 0.0 2.5e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 RLN97764.1 - 0.037 14.4 0.2 0.078 13.3 0.2 1.4 1 0 0 1 1 1 0 Thioesterase superfamily Acyl-ACP_TE PF01643.17 RLN97764.1 - 0.17 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Acyl-ACP thioesterase PCNA_N PF00705.18 RLN97765.1 - 5.8e-28 97.2 0.0 6.3e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Aldo_ket_red PF00248.21 RLN97766.1 - 2.3e-45 155.0 0.4 3.7e-43 147.8 0.4 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family UFD1 PF03152.14 RLN97767.1 - 2.3e-18 66.3 0.0 3e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Coatamer_beta_C PF07718.12 RLN97768.1 - 0.029 14.3 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Coatomer beta C-terminal region BOP1NT PF08145.12 RLN97770.1 - 1.3e-77 261.2 5.2 1.9e-77 260.8 5.2 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 RLN97770.1 - 3.5e-26 90.9 7.7 1.7e-07 31.8 0.0 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN97770.1 - 4.9e-10 39.6 0.2 0.0045 17.3 0.0 4.9 2 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 RLN97770.1 - 0.0076 14.6 0.0 0.013 13.9 0.0 1.3 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 RLN97770.1 - 0.15 12.6 0.0 0.75 10.4 0.0 2.2 2 0 0 2 2 2 0 PQQ-like domain BOP1NT PF08145.12 RLN97772.1 - 9.8e-10 38.8 0.9 9.8e-10 38.8 0.9 1.9 2 1 0 2 2 2 1 BOP1NT (NUC169) domain CDC27 PF09507.10 RLN97772.1 - 0.00097 18.6 29.6 0.0011 18.4 29.6 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Cwf_Cwc_15 PF04889.12 RLN97772.1 - 0.0022 17.7 24.8 0.0036 17.1 24.8 1.4 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 RLN97772.1 - 0.014 14.8 28.8 0.019 14.3 28.8 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 RLN97772.1 - 0.04 12.2 26.2 0.05 11.8 26.2 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RLN97772.1 - 1.1 7.4 20.4 1.3 7.2 20.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 RLN97772.1 - 1.2 8.0 10.4 1.9 7.4 10.4 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hamartin PF04388.12 RLN97772.1 - 1.7 7.2 9.7 1.9 7.1 9.7 1.0 1 0 0 1 1 1 0 Hamartin protein CNDH2_C PF16858.5 RLN97772.1 - 9.5 6.0 23.2 23 4.7 23.4 1.5 1 1 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term LAP1C PF05609.12 RLN97772.1 - 9.6 5.2 19.5 12 4.8 19.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PH PF00169.29 RLN97773.1 - 0.019 15.5 0.0 0.047 14.2 0.0 1.7 1 0 0 1 1 1 0 PH domain FYVE PF01363.21 RLN97773.1 - 0.096 12.8 7.1 0.2 11.8 7.1 1.5 1 0 0 1 1 1 0 FYVE zinc finger Aldo_ket_red PF00248.21 RLN97774.1 - 1.2e-68 231.4 0.0 1.4e-68 231.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TPR_2 PF07719.17 RLN97775.1 - 1.6e-11 43.4 0.0 0.002 18.1 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN97775.1 - 3.4e-09 36.2 0.0 0.053 13.2 0.0 3.6 2 2 1 3 3 3 3 TPR repeat TPR_1 PF00515.28 RLN97775.1 - 1.3e-08 34.3 0.0 0.0012 18.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN97775.1 - 5.7e-08 33.3 8.3 0.00015 22.4 1.9 3.1 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN97775.1 - 1.1e-07 32.0 11.1 0.011 16.5 0.0 4.3 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 RLN97775.1 - 1.9e-07 31.0 0.0 0.034 14.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN97775.1 - 8.2e-07 28.8 0.0 0.041 14.1 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN97775.1 - 8.3e-07 29.2 5.3 0.0015 18.8 0.8 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN97775.1 - 6.1e-06 25.9 2.9 0.0078 16.2 0.1 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN97775.1 - 7.8e-06 26.3 3.5 0.066 13.7 0.4 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 RLN97775.1 - 0.00045 20.0 0.4 0.2 11.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 RLN97775.1 - 0.0089 16.6 6.7 0.15 12.8 0.1 3.7 3 0 0 3 3 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN97775.1 - 0.042 14.1 0.0 0.92 9.8 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 RLN97775.1 - 0.2 11.8 9.3 1 9.5 2.4 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.7 RLN97776.1 - 1.3e-08 35.4 1.3 4.9e-08 33.4 0.2 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN97776.1 - 1.5e-05 25.2 3.3 0.1 12.9 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN97776.1 - 2e-05 25.0 1.1 6.6e-05 23.4 0.4 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN97776.1 - 0.0011 19.2 3.9 2 9.2 0.1 4.3 4 0 0 4 4 4 1 Ankyrin repeat PX PF00787.24 RLN97778.1 - 2.3e-09 37.2 0.2 2.9e-09 36.9 0.2 1.3 1 0 0 1 1 1 1 PX domain Metallophos PF00149.28 RLN97779.1 - 2.3e-14 54.4 0.0 2.9e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RLN97779.1 - 1.5e-08 35.0 0.0 4.3e-08 33.5 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 RLN97779.1 - 0.0084 15.5 0.0 0.017 14.4 0.0 1.5 1 1 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily Nop14 PF04147.12 RLN97780.1 - 0.44 8.7 6.4 0.4 8.9 6.4 1.0 1 0 0 1 1 1 0 Nop14-like family LysM PF01476.20 RLN97781.1 - 1.5e-24 85.8 0.0 2.1e-08 34.1 0.0 4.2 4 0 0 4 4 4 4 LysM domain Ctr PF04145.15 RLN97782.1 - 1.1e-21 78.0 0.3 1.7e-21 77.4 0.3 1.3 1 0 0 1 1 1 1 Ctr copper transporter family PetM PF08041.11 RLN97782.1 - 0.0058 16.2 1.9 0.0058 16.2 1.9 2.0 2 0 0 2 2 2 1 PetM family of cytochrome b6f complex subunit 7 zf-Di19 PF05605.12 RLN97782.1 - 0.0097 16.2 0.4 6.7 7.1 0.1 2.7 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding OrfB_Zn_ribbon PF07282.11 RLN97782.1 - 0.018 15.0 0.5 0.47 10.4 0.0 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain UPF0220 PF05255.11 RLN97782.1 - 0.089 12.3 0.3 0.089 12.3 0.3 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0220) Rad50_zn_hook PF04423.14 RLN97782.1 - 0.1 12.5 0.7 3.1 7.7 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2_3 PF13878.6 RLN97782.1 - 0.21 11.4 1.2 4.9 7.0 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Zn-C2H2_12 PF18112.1 RLN97782.1 - 0.51 10.9 6.5 12 6.4 0.2 3.5 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_2 PF13465.6 RLN97782.1 - 0.79 10.3 3.6 6.4 7.4 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger double domain Ctr PF04145.15 RLN97783.1 - 1.8e-15 57.8 18.0 1.5e-14 54.9 13.4 2.7 2 1 0 2 2 2 1 Ctr copper transporter family HMA PF00403.26 RLN97783.1 - 3.3e-08 33.8 0.1 7.2e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain DivIC PF04977.15 RLN97785.1 - 0.0025 17.5 1.9 0.41 10.5 0.1 2.2 2 0 0 2 2 2 2 Septum formation initiator DUF1192 PF06698.11 RLN97785.1 - 0.027 14.5 0.2 0.1 12.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) FPP PF05911.11 RLN97785.1 - 0.045 11.9 0.2 0.055 11.6 0.2 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil UPF0242 PF06785.11 RLN97785.1 - 0.086 12.9 0.2 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 RLN97785.1 - 0.15 12.6 3.2 0.45 11.0 3.2 1.8 1 1 0 1 1 1 0 Cell division protein ZapB DUSP PF06337.12 RLN97786.1 - 2.8e-08 34.3 0.0 5.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 DUSP domain PDZ PF00595.24 RLN97786.1 - 0.13 12.6 0.2 0.61 10.5 0.1 2.1 2 0 0 2 2 2 0 PDZ domain T2SSC PF11356.8 RLN97786.1 - 0.18 11.7 0.8 0.46 10.4 0.0 2.0 2 0 0 2 2 2 0 Type II secretion system protein C NADH_dh_m_C1 PF15088.6 RLN97787.1 - 4.6e-05 22.9 7.6 0.29 10.8 0.1 4.5 4 0 0 4 4 4 2 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial YbjM PF11045.8 RLN97787.1 - 0.0074 16.4 26.1 0.051 13.7 5.2 3.8 3 0 0 3 3 3 2 Putative inner membrane protein of Enterobacteriaceae DUF4926 PF16277.5 RLN97787.1 - 0.14 11.5 0.1 25 4.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4926) MIF4G PF02854.19 RLN97788.1 - 1.3e-41 142.6 9.0 5.8e-28 98.0 4.9 2.5 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.17 RLN97788.1 - 1.1e-05 25.4 3.6 3.9e-05 23.6 0.9 2.9 3 0 0 3 3 3 1 MA3 domain AAA_assoc_C PF09821.9 RLN97788.1 - 0.043 14.4 1.4 3.5 8.2 0.0 2.9 2 1 0 2 2 2 0 C-terminal AAA-associated domain AAR2 PF05282.11 RLN97789.1 - 5.7e-23 81.9 0.0 6.8e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein DUF402 PF04167.13 RLN97789.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF402) BAR_3 PF16746.5 RLN97791.1 - 2.9e-06 27.2 7.4 7.4e-06 25.8 7.4 1.5 1 1 0 1 1 1 1 BAR domain of APPL family DUF4745 PF15923.5 RLN97791.1 - 0.017 15.1 1.5 0.025 14.6 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4745) DUF4398 PF14346.6 RLN97791.1 - 0.017 15.7 6.7 0.017 15.7 6.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) DUF4695 PF15766.5 RLN97791.1 - 0.86 9.9 4.3 3 8.1 0.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4695) SF1-HH PF16275.5 RLN97791.1 - 2 8.8 3.9 21 5.5 3.9 2.6 1 1 0 1 1 1 0 Splicing factor 1 helix-hairpin domain Arfaptin PF06456.13 RLN97791.1 - 5 6.6 7.5 0.73 9.4 0.3 2.1 2 0 0 2 2 2 0 Arfaptin-like domain APG6_N PF17675.1 RLN97791.1 - 8.5 6.9 9.9 13 6.3 0.5 2.4 2 1 0 2 2 2 0 Apg6 coiled-coil region Ribosomal_S20p PF01649.18 RLN97792.1 - 0.27 11.9 4.2 0.34 11.6 4.2 1.2 1 0 0 1 1 1 0 Ribosomal protein S20 CDC37_N PF03234.14 RLN97792.1 - 0.58 11.1 7.1 0.74 10.7 6.9 1.4 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Acyl_transf_1 PF00698.21 RLN97793.1 - 4.7e-29 101.9 3.5 5.6e-29 101.6 3.5 1.1 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 RLN97793.1 - 0.12 12.1 2.6 0.67 9.6 2.6 2.0 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Pkinase PF00069.25 RLN97795.1 - 7.7e-21 74.6 0.0 7.8e-12 45.1 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain zf-MIZ PF02891.20 RLN97795.1 - 1.2e-13 50.6 1.6 2.3e-13 49.6 1.6 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Pkinase_Tyr PF07714.17 RLN97795.1 - 1.1e-10 41.3 0.0 9.6e-07 28.3 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase SAP PF02037.27 RLN97795.1 - 3.7e-06 26.5 0.1 8e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 SAP domain DUF3449 PF11931.8 RLN97796.1 - 3.9e-74 248.5 1.2 3.9e-74 248.5 1.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 RLN97796.1 - 5e-17 62.2 0.2 1.5e-16 60.6 0.2 1.8 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 RLN97796.1 - 9.4e-11 41.4 0.1 3.6e-10 39.5 0.1 2.1 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 RLN97796.1 - 1.8e-09 37.7 7.8 4.2e-09 36.5 3.0 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RLN97796.1 - 8.2e-09 35.5 3.6 8.2e-09 35.5 3.6 3.3 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 RLN97796.1 - 0.00086 19.6 7.2 0.0025 18.1 0.0 3.7 3 1 0 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 RLN97796.1 - 0.055 13.6 0.8 0.055 13.6 0.8 2.8 2 0 0 2 2 2 0 DBF zinc finger zf-C2H2_4 PF13894.6 RLN97796.1 - 1.2 10.1 10.8 2 9.5 0.8 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 RLN97796.1 - 4.3 8.0 7.0 7.4 7.2 1.9 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type UCR_14kD PF02271.16 RLN97797.1 - 0.045 13.7 0.2 0.29 11.1 0.0 2.3 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF1772 PF08592.11 RLN97798.1 - 7.9e-22 78.0 3.9 1.1e-21 77.6 3.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Sulfate_transp PF00916.20 RLN97798.1 - 0.0041 15.9 0.0 0.0052 15.6 0.0 1.0 1 0 0 1 1 1 1 Sulfate permease family HMMR_N PF15905.5 RLN97801.1 - 0.0089 15.5 0.8 0.011 15.2 0.8 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal CENP-Q PF13094.6 RLN97801.1 - 0.01 16.1 2.2 0.014 15.6 2.2 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.9 RLN97801.1 - 0.019 14.0 0.7 0.023 13.8 0.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Parathyroid PF01279.17 RLN97801.1 - 0.04 14.5 0.1 0.062 13.9 0.1 1.3 1 0 0 1 1 1 0 Parathyroid hormone family GBP_C PF02841.14 RLN97801.1 - 0.05 13.0 2.6 0.061 12.7 2.6 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain LXG PF04740.12 RLN97801.1 - 0.08 12.6 1.3 0.11 12.1 1.3 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily Nop25 PF09805.9 RLN97801.1 - 3.8 8.0 7.8 6.2 7.3 7.8 1.5 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) DFF40 PF09230.10 RLN97803.1 - 0.22 11.1 1.8 0.39 10.3 1.8 1.3 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa Mto2_bdg PF12808.7 RLN97805.1 - 0.23 11.8 5.6 0.081 13.2 1.9 2.1 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region PspB PF06667.12 RLN97805.1 - 0.62 10.2 4.0 0.63 10.1 0.2 2.4 2 0 0 2 2 2 0 Phage shock protein B GP40 PF11025.8 RLN97806.1 - 0.069 12.9 0.2 0.16 11.7 0.2 1.6 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium GAS PF13851.6 RLN97808.1 - 0.046 13.1 5.6 1.8 7.9 0.1 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4224 PF13986.6 RLN97808.1 - 0.12 12.3 0.2 0.61 10.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) Peptidase_C2 PF00648.21 RLN97808.1 - 1.8 7.5 4.2 0.52 9.3 0.2 2.0 2 1 0 2 2 2 0 Calpain family cysteine protease Neur_chan_memb PF02932.16 RLN97808.1 - 7.4 6.6 5.8 13 5.7 5.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region V_ATPase_I PF01496.19 RLN97808.1 - 9.9 3.9 5.5 13 3.5 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Aldo_ket_red PF00248.21 RLN97809.1 - 1.2e-29 103.5 0.0 1.3e-29 103.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3715 PF12509.8 RLN97809.1 - 0.15 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3715) Lebercilin PF15619.6 RLN97811.1 - 0.24 11.0 15.0 0.58 9.8 4.6 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF5320 PF17253.2 RLN97811.1 - 0.49 11.5 4.0 0.64 11.1 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF1043 PF06295.12 RLN97811.1 - 0.95 9.5 5.5 0.19 11.7 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) End3 PF12761.7 RLN97811.1 - 1.1 9.4 14.0 5.8 7.0 13.8 2.0 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 TMF_DNA_bd PF12329.8 RLN97811.1 - 1.4 9.0 10.0 0.3 11.1 2.4 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 RLN97811.1 - 1.6 8.6 14.1 0.42 10.4 5.3 2.5 2 0 0 2 2 2 0 Septum formation initiator TSC22 PF01166.18 RLN97811.1 - 1.8 9.0 6.3 3.3 8.1 0.9 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family Seryl_tRNA_N PF02403.22 RLN97811.1 - 1.9 8.8 7.6 1.5 9.1 5.6 1.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain bZIP_2 PF07716.15 RLN97811.1 - 3 8.0 15.4 11 6.2 1.0 2.9 2 0 0 2 2 2 0 Basic region leucine zipper DUF4140 PF13600.6 RLN97811.1 - 6.7 7.2 10.4 0.87 10.1 3.5 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Csm1_N PF18504.1 RLN97811.1 - 7 7.1 15.0 7.3 7.0 4.8 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF5384 PF17358.2 RLN97812.1 - 0.017 15.2 0.9 0.027 14.5 0.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5384) FadA PF09403.10 RLN97812.1 - 0.17 12.4 5.8 0.14 12.6 4.0 1.7 2 0 0 2 2 2 0 Adhesion protein FadA Sec20 PF03908.13 RLN97812.1 - 0.27 11.2 2.2 0.32 10.9 1.2 1.6 2 0 0 2 2 2 0 Sec20 Trimer_CC PF08954.11 RLN97813.1 - 0.012 15.2 2.9 0.069 12.7 0.7 2.7 2 0 0 2 2 2 0 Trimerisation motif DUF3138 PF11336.8 RLN97813.1 - 0.14 10.8 2.2 0.25 9.9 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) TolA_bind_tri PF16331.5 RLN97813.1 - 0.85 9.7 6.8 0.1 12.7 1.3 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation GrpE PF01025.19 RLN97813.1 - 1.8 8.2 5.4 14 5.3 0.2 2.5 2 1 0 2 2 2 0 GrpE BLOC1_2 PF10046.9 RLN97814.1 - 0.00048 20.4 7.1 0.0033 17.7 0.6 2.4 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 LCIB_C_CA PF18599.1 RLN97814.1 - 0.026 13.8 1.6 0.1 11.9 0.3 2.0 1 1 1 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases FapA PF03961.13 RLN97814.1 - 0.03 12.9 1.9 0.041 12.5 1.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-C4H2 PF10146.9 RLN97814.1 - 0.047 14.0 2.7 0.059 13.7 2.7 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein ERM PF00769.19 RLN97814.1 - 0.09 12.6 13.1 0.14 11.9 13.1 1.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF1515 PF07439.11 RLN97814.1 - 0.12 12.4 5.2 0.21 11.6 0.9 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) DUF16 PF01519.16 RLN97814.1 - 0.21 12.1 8.3 0.18 12.3 3.9 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 Atg14 PF10186.9 RLN97814.1 - 0.32 10.0 8.0 0.45 9.6 8.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 RLN97814.1 - 0.4 10.7 6.9 1.1 9.4 6.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) OmpH PF03938.14 RLN97814.1 - 0.49 10.7 9.8 0.76 10.1 9.8 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.10 RLN97814.1 - 0.55 10.4 9.5 1 9.6 8.3 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.8 RLN97814.1 - 1.2 8.3 14.5 0.32 10.3 10.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF883 PF05957.13 RLN97814.1 - 2.1 9.0 9.7 4.8 7.9 0.9 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) JIP_LZII PF16471.5 RLN97814.1 - 3.6 7.8 9.2 1.2 9.4 3.5 2.6 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II ThiF PF00899.21 RLN97815.1 - 1.9e-62 210.8 0.1 2.9e-62 210.2 0.1 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 RLN97815.1 - 3.6e-20 71.9 0.0 6.5e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 RLN97815.1 - 0.0029 18.1 0.0 0.0057 17.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.20 RLN97815.1 - 0.034 14.2 0.1 0.1 12.6 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_19 PF00182.19 RLN97816.1 - 2.6e-49 168.2 3.3 4e-48 164.3 3.3 2.2 1 1 0 1 1 1 1 Chitinase class I Palm_thioest PF02089.15 RLN97817.1 - 3.1e-24 86.1 1.7 3.6e-24 85.9 1.7 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase HTH_48 PF17906.1 RLN97818.1 - 0.082 13.0 0.0 1 9.5 0.0 2.4 2 0 0 2 2 2 0 HTH domain in Mos1 transposase Glyco_hydro_31 PF01055.26 RLN97819.1 - 9e-24 84.4 0.3 1.9e-23 83.4 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 RLN97819.1 - 0.0047 17.2 0.0 0.016 15.5 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Pex24p PF06398.11 RLN97820.1 - 2.1e-05 23.7 0.9 5.9e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin PUB PF09409.10 RLN97820.1 - 0.063 13.2 0.1 0.35 10.8 0.0 2.3 2 0 0 2 2 2 0 PUB domain HALZ PF02183.18 RLN97820.1 - 0.065 13.5 0.6 0.065 13.5 0.6 4.4 7 0 0 7 7 7 0 Homeobox associated leucine zipper Phage_mat-A PF03863.13 RLN97820.1 - 0.09 11.7 1.6 0.15 10.9 1.6 1.3 1 0 0 1 1 1 0 Phage maturation protein FlaC_arch PF05377.11 RLN97820.1 - 0.34 11.3 4.8 3.7 8.0 0.2 4.0 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) ACT_7 PF13840.6 RLN97821.1 - 3.9e-21 74.6 0.1 1.3e-12 47.3 0.0 2.3 2 0 0 2 2 2 2 ACT domain Castor1_N PF18700.1 RLN97821.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain zf-CCCH PF00642.24 RLN97822.1 - 0.024 14.6 0.6 4.8 7.2 0.1 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HCNGP PF07818.13 RLN97823.1 - 2.1e-25 89.2 0.0 3.3e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 HCNGP-like protein Aa_trans PF01490.18 RLN97824.1 - 1.7e-58 198.3 18.7 2.2e-58 197.9 18.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 RLN97824.1 - 1.7e-09 37.0 31.7 1.4e-05 24.1 15.7 2.0 2 0 0 2 2 2 2 Amino acid permease Trp_Tyr_perm PF03222.13 RLN97824.1 - 3.2e-08 33.0 15.7 3.2e-08 33.0 15.7 1.6 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Sel1 PF08238.12 RLN97825.1 - 3.5e-38 129.2 10.8 1.7e-10 41.2 0.1 6.0 6 0 0 6 6 6 5 Sel1 repeat TPR_16 PF13432.6 RLN97825.1 - 3.8 8.2 8.3 8.9 7.1 0.2 3.0 2 2 1 3 3 3 0 Tetratricopeptide repeat Med3 PF11593.8 RLN97827.1 - 4.5 6.4 8.6 7.3 5.7 8.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TPR_1 PF00515.28 RLN97828.1 - 6.5e-18 63.7 0.7 0.0013 18.5 0.0 5.2 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 RLN97828.1 - 5.2e-17 60.5 2.3 0.00013 21.8 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 RLN97828.1 - 1.1e-06 29.2 3.6 0.0047 17.5 3.4 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 RLN97828.1 - 2e-06 28.0 0.2 2.1 9.1 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN97828.1 - 3.6e-06 26.7 0.0 0.81 10.1 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 RLN97828.1 - 1.2e-05 24.8 0.9 0.03 14.0 0.0 3.9 3 1 1 4 4 4 1 TPR repeat TPR_9 PF13371.6 RLN97828.1 - 2e-05 24.7 7.5 9.6e-05 22.5 0.8 3.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN97828.1 - 3e-05 24.4 4.1 0.017 15.6 0.0 3.9 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN97828.1 - 3.2e-05 24.0 0.1 0.064 13.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN97828.1 - 0.011 16.4 4.9 14 6.8 0.0 4.1 2 2 2 4 4 4 0 Tetratricopeptide repeat NARP1 PF12569.8 RLN97828.1 - 0.013 14.4 2.2 0.033 13.1 1.2 1.8 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 TPR_12 PF13424.6 RLN97828.1 - 0.015 15.6 9.8 0.23 11.7 0.3 4.0 2 2 1 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN97828.1 - 0.14 12.4 0.3 0.14 12.4 0.3 3.4 2 2 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 RLN97829.1 - 1.6e-41 138.4 30.4 2.7e-06 26.9 1.4 13.0 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_11 PF13414.6 RLN97829.1 - 1.3e-35 120.8 8.4 4.9e-07 29.3 0.0 9.5 6 2 4 10 10 10 6 TPR repeat TPR_2 PF07719.17 RLN97829.1 - 3.8e-34 114.0 39.1 3.7e-05 23.5 0.1 13.2 14 0 0 14 14 13 7 Tetratricopeptide repeat TPR_17 PF13431.6 RLN97829.1 - 4e-18 64.4 18.5 0.013 15.8 0.0 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 RLN97829.1 - 4.5e-18 63.9 11.4 0.02 15.1 0.0 9.8 12 0 0 12 12 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 RLN97829.1 - 9.5e-16 57.9 40.4 3.7e-06 27.1 0.0 9.3 4 3 4 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.6 RLN97829.1 - 9.1e-14 51.8 43.3 0.0024 18.5 0.0 8.2 5 3 2 8 8 8 6 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN97829.1 - 3.6e-11 43.1 13.3 0.0073 16.5 0.1 6.0 4 1 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 RLN97829.1 - 2.8e-10 40.1 21.7 0.23 12.1 0.0 9.7 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN97829.1 - 3.2e-10 39.3 25.0 0.014 15.3 0.0 9.0 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 RLN97829.1 - 5.1e-10 39.4 45.6 0.0013 18.9 4.7 9.3 6 3 5 11 11 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 RLN97829.1 - 1.7e-09 37.7 40.4 0.053 14.4 0.1 11.1 6 4 6 12 12 12 3 Tetratricopeptide repeat TPR_15 PF13429.6 RLN97829.1 - 1.2e-07 31.2 5.4 0.5 9.5 0.1 5.1 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 RLN97829.1 - 2.5e-06 27.9 0.3 0.0045 17.5 0.0 6.5 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.6 RLN97829.1 - 5.3e-05 23.5 4.3 0.17 12.2 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 RLN97829.1 - 0.00043 20.6 24.6 0.16 12.6 0.9 6.4 6 0 0 6 6 4 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN97829.1 - 0.00063 19.8 0.2 6.9 6.8 0.0 4.3 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.8 RLN97829.1 - 0.0034 16.4 0.1 13 4.6 0.0 4.0 3 1 1 4 4 4 0 NMDA receptor-regulated protein 1 PaREP1 PF05942.11 RLN97829.1 - 0.0052 16.7 1.2 1.1 9.2 0.2 2.4 2 0 0 2 2 2 1 Archaeal PaREP1/PaREP8 family TPR_21 PF09976.9 RLN97829.1 - 0.042 13.6 4.9 0.77 9.4 0.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat-like domain BTAD PF03704.17 RLN97829.1 - 0.084 13.3 0.1 0.084 13.3 0.1 4.8 3 2 1 4 4 4 0 Bacterial transcriptional activator domain PPTA PF01239.22 RLN97829.1 - 0.1 12.3 0.0 29 4.6 0.0 3.7 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat DUF5113 PF17140.4 RLN97829.1 - 0.28 11.0 0.9 1.2e+02 2.4 0.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF5113) TPR_10 PF13374.6 RLN97829.1 - 6.4 6.8 27.7 7.4 6.6 0.0 9.1 10 0 0 10 10 9 0 Tetratricopeptide repeat CBS PF00571.28 RLN97832.1 - 1.1e-18 67.3 0.2 4.3e-09 36.7 0.1 2.2 2 0 0 2 2 2 2 CBS domain GAF_2 PF13185.6 RLN97832.1 - 0.012 15.9 0.0 0.02 15.2 0.0 1.3 1 1 0 1 1 1 0 GAF domain PRC PF05239.16 RLN97832.1 - 0.02 15.0 0.9 0.12 12.5 0.1 2.2 2 0 0 2 2 2 0 PRC-barrel domain Exo_endo_phos PF03372.23 RLN97833.1 - 5.9e-11 42.3 0.0 2e-10 40.6 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 7tm_2 PF00002.24 RLN97833.1 - 6.3e-08 32.2 2.9 1.1e-07 31.4 2.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 RLN97833.1 - 0.00036 20.0 0.2 0.00052 19.4 0.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 RLN97833.1 - 0.00087 18.5 3.1 0.0014 17.8 3.1 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Ion_trans PF00520.31 RLN97833.1 - 0.57 9.4 8.2 1.1 8.4 8.2 1.5 1 1 0 1 1 1 0 Ion transport protein mRNA_cap_enzyme PF01331.19 RLN97834.1 - 1.5e-31 109.8 0.1 2.3e-31 109.2 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.21 RLN97834.1 - 2.7e-08 33.7 0.0 4.1e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain tRNA_synthFbeta PF17759.1 RLN97835.1 - 1.3e-48 165.3 0.0 1.4e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B5 PF03484.15 RLN97835.1 - 7.9e-05 22.9 0.1 0.00034 20.9 0.1 2.1 2 1 0 2 2 2 1 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 RLN97835.1 - 0.076 12.5 0.0 3.1 7.2 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Cep57_CLD_2 PF14197.6 RLN97836.1 - 0.11 12.6 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Dimer_Tnp_hAT PF05699.14 RLN97839.1 - 2.8e-15 55.9 0.0 8.4e-15 54.3 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 RLN97839.1 - 6.3e-05 22.9 0.0 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Pkinase PF00069.25 RLN97840.1 - 4.2e-63 213.2 0.0 6.3e-63 212.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97840.1 - 7.6e-39 133.6 0.0 1.4e-38 132.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 RLN97840.1 - 2.9e-35 121.0 1.6 3e-15 56.6 0.1 3.8 3 0 0 3 3 3 3 PH domain PH_8 PF15409.6 RLN97840.1 - 4.8e-08 33.2 7.3 0.00027 21.1 0.3 3.8 4 0 0 4 4 4 2 Pleckstrin homology domain PH_11 PF15413.6 RLN97840.1 - 2.9e-07 30.9 14.9 0.0007 20.0 2.7 4.3 3 3 1 4 4 4 2 Pleckstrin homology domain PH_3 PF14593.6 RLN97840.1 - 1.8e-06 28.0 0.1 0.014 15.5 0.0 3.1 1 1 2 3 3 3 2 PH domain zf-ribbon_3 PF13248.6 RLN97840.1 - 0.0003 20.1 1.9 0.00062 19.1 1.9 1.6 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 RLN97840.1 - 0.02 14.9 0.8 0.046 13.7 0.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon Kdo PF06293.14 RLN97840.1 - 0.048 13.0 0.1 0.083 12.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zinc_ribbon_2 PF13240.6 RLN97840.1 - 0.18 11.5 4.2 0.4 10.5 4.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 RLN97840.1 - 0.21 12.4 0.4 0.45 11.3 0.4 1.5 1 0 0 1 1 1 0 zinc-ribbon family APH PF01636.23 RLN97840.1 - 0.24 11.3 0.6 3 7.7 0.9 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family PH_9 PF15410.6 RLN97840.1 - 8.2 6.8 6.3 80 3.6 0.1 4.3 4 2 0 4 4 4 0 Pleckstrin homology domain Beta_helix PF13229.6 RLN97842.1 - 7.5e-06 25.9 2.9 2e-05 24.5 2.9 1.7 1 0 0 1 1 1 1 Right handed beta helix region DUF1565 PF07602.11 RLN97842.1 - 0.0049 16.3 3.5 0.3 10.4 1.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1565) Pkinase PF00069.25 RLN97844.1 - 5.1e-66 222.7 0.0 6e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97844.1 - 2.7e-29 102.3 0.0 3.7e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN97844.1 - 6.7e-05 22.3 0.1 0.00016 21.1 0.1 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 RLN97844.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RLN97844.1 - 0.15 10.9 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain DAO PF01266.24 RLN97845.1 - 2.8e-29 102.8 0.0 2.2e-28 99.9 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 RLN97845.1 - 2.2e-07 30.3 0.0 0.0052 15.9 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 RLN97845.1 - 0.00043 19.6 0.0 0.002 17.4 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RLN97845.1 - 0.0053 17.0 0.0 0.041 14.1 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 RLN97845.1 - 0.007 15.5 1.1 0.047 12.8 1.1 2.0 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 RLN97845.1 - 0.015 14.5 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 RLN97845.1 - 0.025 13.9 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 RLN97845.1 - 0.032 14.2 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 RLN97845.1 - 0.088 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GlcNAc PF11397.8 RLN97846.1 - 1.2e-61 209.1 1.1 1.4e-27 97.1 0.2 3.2 1 1 2 3 3 3 3 Glycosyltransferase (GlcNAc) 2OG-FeII_Oxy_3 PF13640.6 RLN97846.1 - 1.1e-15 58.2 0.1 2.1e-15 57.4 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 RLN97846.1 - 9.3e-09 35.8 0.0 2.3e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_M20 PF01546.28 RLN97847.1 - 8.5e-16 58.3 0.0 1.6e-15 57.3 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 RLN97847.1 - 2.8e-11 43.3 0.0 1.3e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 Peptidase dimerisation domain Amidohydro_1 PF01979.20 RLN97848.1 - 4.5e-29 101.8 0.0 3.2e-23 82.6 0.0 2.1 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 RLN97848.1 - 0.0065 16.0 0.3 0.29 10.6 0.1 2.7 3 0 0 3 3 3 1 Amidohydrolase family Sec8_exocyst PF04048.14 RLN97849.1 - 4.1e-10 39.7 0.9 4.7e-10 39.5 0.9 1.1 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 RLN97849.1 - 3.5e-06 26.5 0.5 3.9e-06 26.4 0.5 1.0 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Apolipoprotein PF01442.18 RLN97849.1 - 0.015 15.2 3.8 0.023 14.6 3.8 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain TMF_TATA_bd PF12325.8 RLN97849.1 - 0.023 14.9 1.1 0.034 14.4 1.1 1.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DIRP PF06584.13 RLN97849.1 - 0.032 14.4 0.7 0.59 10.3 0.7 2.2 1 1 0 1 1 1 0 DIRP COG2 PF06148.11 RLN97849.1 - 0.05 13.7 0.7 0.079 13.1 0.7 1.5 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 PseudoU_synth_1 PF01416.20 RLN97850.1 - 3.9e-14 53.0 0.2 6.3e-10 39.5 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase Glucodextran_C PF09985.9 RLN97850.1 - 0.022 14.2 0.1 0.027 13.9 0.1 1.2 1 0 0 1 1 1 0 C-terminal binding-module, SLH-like, of glucodextranase WW PF00397.26 RLN97851.1 - 2.4e-14 53.1 3.6 1.4e-06 28.2 0.1 2.5 2 0 0 2 2 2 2 WW domain FF PF01846.19 RLN97851.1 - 8.6e-06 25.8 0.0 1.9e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 FF domain SR-25 PF10500.9 RLN97851.1 - 0.058 13.0 11.0 0.077 12.6 11.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAM60A PF15396.6 RLN97851.1 - 0.15 12.0 6.2 0.22 11.5 6.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Spore_coat_CotO PF14153.6 RLN97851.1 - 0.19 11.7 13.8 0.28 11.1 13.8 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Glyco_hyd_101C PF17451.2 RLN97851.1 - 0.36 11.1 14.2 1.3 9.4 0.2 4.0 2 2 3 5 5 5 0 Glycosyl hydrolase 101 beta sandwich domain SAPS PF04499.15 RLN97851.1 - 1.4 7.6 6.2 1.6 7.4 6.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CRA PF06589.11 RLN97851.1 - 4.1 7.5 9.3 6.7 6.8 9.3 1.2 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) VIR_N PF15912.5 RLN97851.1 - 4.3 6.9 13.0 2.7 7.5 0.1 2.1 2 0 0 2 2 2 0 Virilizer, N-terminal SLC12 PF03522.15 RLN97851.1 - 5 6.0 8.1 6.7 5.6 8.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Paramyxo_ncap PF00973.19 RLN97851.1 - 7.5 5.3 7.7 9.8 5.0 7.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF5382 PF17354.2 RLN97852.1 - 0.019 13.8 0.1 0.024 13.5 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5382) TipAS PF07739.13 RLN97852.1 - 0.41 11.2 4.1 15 6.1 0.1 3.1 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain Pkinase PF00069.25 RLN97853.1 - 6.1e-35 120.9 0.2 7.9e-35 120.5 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97853.1 - 1.2e-19 70.6 0.1 1.6e-19 70.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CLASP_N PF12348.8 RLN97854.1 - 5.5e-21 75.2 0.9 4.9e-14 52.4 0.1 4.1 4 0 0 4 4 4 3 CLASP N terminal Vac14_Fab1_bd PF12755.7 RLN97854.1 - 0.00044 20.8 4.1 4.5 7.9 0.1 5.1 5 1 0 5 5 5 2 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.7 RLN97854.1 - 0.052 13.9 0.2 0.85 10.0 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 RLN97854.1 - 0.062 13.3 8.9 4.1 7.4 0.2 4.9 4 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RLN97854.1 - 1.8 9.1 20.5 6.7 7.3 0.2 7.4 8 0 0 8 8 8 0 HEAT repeat HEAT_EZ PF13513.6 RLN97854.1 - 2.7 8.6 16.7 24 5.6 0.4 6.9 7 0 0 7 7 7 0 HEAT-like repeat HHH_8 PF14716.6 RLN97856.1 - 2.1e-26 92.0 0.7 1.1e-09 38.5 0.0 3.2 3 0 0 3 3 3 3 Helix-hairpin-helix domain NAD_kinase PF01513.21 RLN97857.1 - 6.3e-16 58.4 0.0 9.1e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 RLN97857.1 - 0.0015 18.1 0.8 0.014 15.0 0.8 2.3 2 1 0 2 2 2 1 Diacylglycerol kinase catalytic domain NAD_binding_10 PF13460.6 RLN97857.1 - 0.1 12.5 1.0 0.85 9.5 0.2 2.2 2 0 0 2 2 2 0 NAD(P)H-binding Creatininase PF02633.14 RLN97858.1 - 0.067 12.6 3.5 0.078 12.4 3.5 1.1 1 0 0 1 1 1 0 Creatinine amidohydrolase SET PF00856.28 RLN97858.1 - 0.31 11.4 3.7 0.41 11.0 3.7 1.3 1 1 0 1 1 1 0 SET domain Trypan_glycop PF00913.19 RLN97858.1 - 2.6 7.2 12.3 3.3 6.9 12.3 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) DDHD PF02862.17 RLN97858.1 - 4.4 7.4 5.8 5.3 7.1 5.8 1.1 1 0 0 1 1 1 0 DDHD domain XRN_M PF17846.1 RLN97858.1 - 5.1 5.9 9.8 5.9 5.7 9.8 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Asp-B-Hydro_N PF05279.11 RLN97858.1 - 5.2 7.1 13.0 6.6 6.7 13.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region 4HBT_2 PF13279.6 RLN97859.1 - 4.3e-23 82.1 0.0 5.4e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily AAA_11 PF13086.6 RLN97860.1 - 1.6e-68 231.4 0.9 1.6e-68 231.4 0.9 3.3 4 1 0 4 4 4 1 AAA domain AAA_12 PF13087.6 RLN97860.1 - 9.9e-61 204.8 0.0 2.8e-60 203.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RLN97860.1 - 8.9e-10 38.6 0.4 0.00017 21.4 0.1 2.8 2 0 0 2 2 2 2 AAA domain SEN1_N PF12726.7 RLN97860.1 - 9.7e-09 34.0 0.4 2.2e-08 32.8 0.1 1.8 2 0 0 2 2 2 1 SEN1 N terminal Med26 PF08711.11 RLN97860.1 - 3.8e-07 30.0 3.2 4.4e-07 29.8 1.3 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain AAA_19 PF13245.6 RLN97860.1 - 1e-06 29.1 0.0 0.043 14.2 0.1 2.9 2 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 RLN97860.1 - 0.00023 21.0 0.1 0.24 11.1 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 RLN97860.1 - 0.12 12.4 0.7 0.73 9.8 0.2 2.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) MULE PF10551.9 RLN97861.1 - 0.0042 17.5 0.0 0.0073 16.7 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain AI-2E_transport PF01594.16 RLN97863.1 - 8.7e-28 97.4 16.6 8.7e-28 97.4 16.6 2.1 1 1 1 2 2 2 2 AI-2E family transporter YIEGIA PF14045.6 RLN97863.1 - 0.21 10.4 1.1 0.37 9.6 1.1 1.3 1 0 0 1 1 1 0 YIEGIA protein DUF1640 PF07798.11 RLN97865.1 - 1.8e-07 31.4 4.6 4.1e-07 30.2 4.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) YppF PF14178.6 RLN97865.1 - 0.041 13.7 0.4 0.093 12.6 0.4 1.6 1 0 0 1 1 1 0 YppF-like protein DDE_Tnp_IS240 PF13610.6 RLN97865.1 - 0.061 13.6 0.1 0.096 12.9 0.1 1.4 1 1 0 1 1 1 0 DDE domain Enkurin PF13864.6 RLN97865.1 - 0.23 11.9 6.1 1.4 9.4 0.3 2.2 1 1 1 2 2 2 0 Calmodulin-binding Wbp11 PF09429.10 RLN97865.1 - 6 7.3 7.6 43 4.6 7.6 2.0 1 1 0 1 1 1 0 WW domain binding protein 11 RmlD_sub_bind PF04321.17 RLN97866.1 - 5.4e-09 35.5 0.0 7e-08 31.9 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 RLN97866.1 - 2.5e-07 30.8 0.0 3.8e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 RLN97866.1 - 2.3e-06 27.3 0.0 2.7e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 RLN97866.1 - 0.00027 20.0 0.0 0.079 11.9 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 RLN97866.1 - 0.0012 18.4 0.1 0.0029 17.2 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family MULE PF10551.9 RLN97867.1 - 0.00014 22.2 0.1 0.00046 20.6 0.1 1.8 2 0 0 2 2 2 1 MULE transposase domain LRR_4 PF12799.7 RLN97868.1 - 2.1e-08 34.3 19.7 5.9e-05 23.3 1.1 5.7 1 1 5 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN97868.1 - 2.6e-05 23.9 19.6 0.036 13.8 0.4 5.5 3 1 3 6 6 6 4 Leucine rich repeat LRR_1 PF00560.33 RLN97868.1 - 0.016 15.7 18.5 16 6.5 0.2 7.3 6 2 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 RLN97868.1 - 0.023 14.7 11.8 30 5.0 0.1 6.4 4 2 0 5 5 5 0 Leucine Rich repeat Methyltransf_16 PF10294.9 RLN97869.1 - 4.2e-23 82.0 0.2 1.2e-22 80.4 0.1 1.8 2 0 0 2 2 2 1 Lysine methyltransferase TPR_2 PF07719.17 RLN97869.1 - 4.3e-13 48.3 1.2 0.002 18.1 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN97869.1 - 8.4e-11 41.2 0.8 0.043 13.6 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN97869.1 - 4.8e-10 39.6 4.0 0.0012 19.1 0.0 5.0 4 1 0 4 4 4 3 Tetratricopeptide repeat Glyco_transf_41 PF13844.6 RLN97869.1 - 6.2e-08 31.5 0.1 0.00024 19.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 41 PrmA PF06325.13 RLN97869.1 - 2.7e-06 27.0 0.0 5.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TPR_8 PF13181.6 RLN97869.1 - 5.2e-06 26.2 3.2 0.23 11.8 0.3 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN97869.1 - 5.2e-06 26.1 3.0 1.6 8.9 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN97869.1 - 0.0012 18.7 8.3 9.1 6.3 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN97869.1 - 0.0031 18.2 1.2 72 4.6 0.1 5.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN97869.1 - 0.0032 18.0 0.4 6.2 7.7 0.8 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 RLN97869.1 - 0.0037 16.9 1.5 0.57 9.9 0.0 4.2 5 1 0 5 5 5 1 TPR repeat TPR_17 PF13431.6 RLN97869.1 - 0.0047 17.2 2.2 4.9 7.8 0.0 5.3 7 0 0 7 7 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN97869.1 - 0.0058 17.1 4.2 1.7 9.2 0.1 4.7 3 1 1 5 5 5 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 RLN97869.1 - 0.023 14.6 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal Met_10 PF02475.16 RLN97869.1 - 0.078 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Met-10+ like-protein DSPc PF00782.20 RLN97870.1 - 1.8e-17 63.4 0.1 2.2e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RLN97870.1 - 0.0013 18.4 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 RLN97870.1 - 0.049 13.7 0.1 0.081 13.0 0.1 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.12 RLN97870.1 - 0.081 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) cNMP_binding PF00027.29 RLN97871.1 - 7.8e-16 57.9 1.7 0.03 14.4 0.0 6.8 6 1 0 6 6 6 5 Cyclic nucleotide-binding domain TPR_2 PF07719.17 RLN97872.1 - 4.6e-05 23.2 2.3 0.27 11.5 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN97872.1 - 0.00016 21.7 0.1 1.1 9.7 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN97872.1 - 0.00021 21.8 0.1 0.24 12.3 0.1 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN97872.1 - 0.00039 20.9 0.1 0.00089 19.7 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN97872.1 - 0.0086 16.3 1.6 0.017 15.3 1.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 RLN97872.1 - 0.0092 15.8 0.2 3.5 7.6 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN97872.1 - 0.017 15.2 0.0 0.048 13.8 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 RLN97872.1 - 0.057 12.9 0.1 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 SHNi-TPR RR_TM4-6 PF06459.12 RLN97872.1 - 6.1 6.6 12.0 9.7 5.9 12.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ank_5 PF13857.6 RLN97873.1 - 2.5e-19 69.1 1.8 2.7e-10 40.3 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RLN97873.1 - 4.1e-15 55.9 0.1 1.2e-13 51.3 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN97873.1 - 3.8e-14 53.0 0.0 3.4e-06 27.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RLN97873.1 - 1.3e-12 47.5 0.2 2.7e-05 24.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 RLN97873.1 - 7.2e-12 44.4 0.0 7.5e-05 22.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat zf-C3HC4_3 PF13920.6 RLN97874.1 - 1.6e-14 53.5 9.8 3.6e-14 52.4 9.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 RLN97874.1 - 8.4e-14 51.9 0.0 5e-07 30.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN97874.1 - 1e-12 48.0 1.3 1.4e-10 41.2 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN97874.1 - 1.2e-12 46.8 0.3 5.3e-05 23.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 RLN97874.1 - 1.3e-12 48.0 0.2 1.5e-11 44.6 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 RLN97874.1 - 3.7e-11 42.9 0.5 9.9e-05 22.6 0.0 3.4 4 0 0 4 4 3 2 Ankyrin repeat zf-RING_2 PF13639.6 RLN97874.1 - 8.3e-07 29.2 9.2 8.3e-07 29.2 9.2 1.8 2 0 0 2 2 1 1 Ring finger domain UIM PF02809.20 RLN97874.1 - 7.4e-06 25.5 1.0 2.6e-05 23.8 1.0 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif Prok-RING_4 PF14447.6 RLN97874.1 - 0.00012 21.9 10.8 0.00028 20.7 10.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 RLN97874.1 - 0.001 18.9 11.0 0.0023 17.8 11.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN97874.1 - 0.0066 16.4 9.9 0.015 15.2 9.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 RLN97874.1 - 0.22 11.3 8.7 0.69 9.7 8.7 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 RLN97874.1 - 0.88 9.8 8.6 3.1 8.0 8.7 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING PDZ_6 PF17820.1 RLN97875.1 - 1.3e-06 28.1 1.1 0.0093 15.8 0.1 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 RLN97875.1 - 0.0056 17.0 0.0 0.15 12.4 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Glyoxalase PF00903.25 RLN97876.1 - 5.9e-06 26.5 0.0 6.9e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 RLN97876.1 - 0.003 18.3 0.0 0.0047 17.7 0.0 1.2 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 RLN97876.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase-like domain Sec20 PF03908.13 RLN97877.1 - 0.13 12.2 0.1 0.35 10.8 0.0 1.7 2 0 0 2 2 2 0 Sec20 AA_permease_2 PF13520.6 RLN97878.1 - 6.8e-45 153.7 35.3 6.8e-45 153.7 35.3 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN97878.1 - 2.1e-32 112.3 43.0 3.1e-31 108.5 32.2 2.2 1 1 1 2 2 2 2 Amino acid permease AA_permease_C PF13906.6 RLN97878.1 - 1.5e-14 53.8 0.3 1.5e-14 53.8 0.3 3.4 4 0 0 4 4 4 1 C-terminus of AA_permease DUF2070 PF09843.9 RLN97878.1 - 2.8 6.1 25.0 3.1 6.0 15.4 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) zf-BED PF02892.15 RLN97879.1 - 0.018 15.1 1.6 0.054 13.5 1.6 1.8 1 1 0 1 1 1 0 BED zinc finger GHMP_kinases_N PF00288.26 RLN97880.1 - 3.5e-14 52.8 3.4 7.5e-14 51.7 3.4 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 RLN97880.1 - 0.00019 21.7 0.1 0.00019 21.7 0.1 2.2 2 0 0 2 2 2 1 GHMP kinases C terminal DnaJ PF00226.31 RLN97881.1 - 2.1e-25 88.6 0.8 3.5e-25 87.9 0.8 1.4 1 0 0 1 1 1 1 DnaJ domain RED_N PF07808.13 RLN97883.1 - 2.5e-35 122.2 5.8 2.5e-35 122.2 5.8 3.6 2 2 0 2 2 2 1 RED-like protein N-terminal region RNR_Alpha PF17975.1 RLN97883.1 - 0.035 14.6 2.4 0.068 13.7 1.5 2.0 1 1 0 1 1 1 0 Ribonucleotide reductase alpha domain tRNA-synt_1g PF09334.11 RLN97886.1 - 6.3e-100 334.7 0.3 2.1e-99 333.0 0.3 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 RLN97886.1 - 3.5e-25 88.3 1.2 5.2e-14 51.4 0.6 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 RLN97886.1 - 1.4e-11 44.3 0.1 8.5e-05 22.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 RLN97886.1 - 0.092 11.6 0.0 0.26 10.2 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (K) CP_ATPgrasp_1 PF04174.13 RLN97886.1 - 0.098 11.7 0.0 0.44 9.5 0.0 1.9 2 0 0 2 2 2 0 A circularly permuted ATPgrasp DUF966 PF06136.13 RLN97890.1 - 5 6.7 5.9 6.5 6.4 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Asp PF00026.23 RLN97891.1 - 7.3e-21 74.9 0.1 6.5e-20 71.8 0.1 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RLN97891.1 - 1.3e-15 58.1 1.0 2e-15 57.5 1.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 RLN97891.1 - 1.2e-10 41.4 0.0 2.3e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Zip PF02535.22 RLN97892.1 - 1.3e-29 103.5 7.1 4.2e-29 101.8 7.1 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter DUF1190 PF06693.11 RLN97892.1 - 0.071 13.5 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) adh_short PF00106.25 RLN97893.1 - 9.4e-33 113.3 1.1 2.3e-28 99.0 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN97893.1 - 3.6e-21 75.8 0.4 1e-20 74.3 0.4 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN97893.1 - 2.1e-11 44.1 0.1 3.1e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN97893.1 - 2.2e-05 24.1 0.1 2.8e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 RLN97893.1 - 0.00034 20.0 0.0 0.00044 19.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.6 RLN97893.1 - 0.0046 16.9 0.3 0.014 15.3 0.3 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 RLN97893.1 - 0.09 13.0 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 RLN97894.1 - 7e-32 110.5 0.2 5.3e-28 97.8 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RLN97894.1 - 8.2e-20 71.4 0.3 1.2e-19 70.8 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN97894.1 - 3.3e-10 40.2 0.2 4.7e-10 39.7 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RLN97894.1 - 0.00016 21.2 0.1 0.00021 20.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 RLN97894.1 - 0.0035 16.6 0.1 0.0072 15.6 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 RLN97894.1 - 0.012 15.9 0.1 0.02 15.2 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 RLN97894.1 - 0.014 15.3 0.8 0.037 13.9 0.8 1.7 1 1 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 RLN97894.1 - 0.11 12.4 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 RLN97894.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase RNA_POL_M_15KD PF02150.16 RLN97895.1 - 1.1e-05 25.2 0.3 1.1e-05 25.2 0.3 2.0 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit zinc_ribbon_10 PF10058.9 RLN97895.1 - 0.0045 16.7 0.8 0.94 9.3 0.0 2.7 2 1 0 2 2 2 2 Predicted integral membrane zinc-ribbon metal-binding protein CpXC PF14353.6 RLN97895.1 - 0.0096 16.0 2.1 0.26 11.3 0.1 2.2 2 0 0 2 2 2 1 CpXC protein TFIIS_C PF01096.18 RLN97895.1 - 0.014 15.2 2.5 0.71 9.8 0.5 2.5 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 RLN97895.1 - 0.023 14.6 0.9 2 8.4 0.2 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain RNase_Zc3h12a_2 PF14626.6 RLN97895.1 - 0.045 14.0 0.0 0.057 13.6 0.0 1.1 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain Ribosomal_S27e PF01667.17 RLN97895.1 - 0.061 13.0 0.6 0.38 10.5 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein S27 Elf1 PF05129.13 RLN97895.1 - 0.088 12.9 1.0 6.4 6.9 0.1 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-LITAF-like PF10601.9 RLN97895.1 - 0.095 13.0 0.9 0.87 9.9 0.2 2.1 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.10 RLN97895.1 - 0.11 12.6 4.0 9.4 6.5 1.5 2.4 2 0 0 2 2 2 0 Zinc ribbon domain ABC_tran PF00005.27 RLN97896.1 - 2e-31 109.3 0.0 3.4e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 RLN97896.1 - 2.1e-14 53.8 17.6 6.9e-14 52.1 17.6 1.8 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 RLN97896.1 - 1e-07 31.6 0.1 1.4e-06 27.9 0.1 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DEAD PF00270.29 RLN97896.1 - 0.0084 15.9 1.2 0.044 13.5 1.2 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase ATP-synt_ab PF00006.25 RLN97896.1 - 0.016 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 RLN97896.1 - 0.02 15.1 0.5 5 7.4 0.7 2.7 1 1 1 2 2 2 0 AAA domain DUF87 PF01935.17 RLN97896.1 - 0.024 14.7 0.5 0.06 13.4 0.5 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 RLN97896.1 - 0.036 14.3 1.0 0.19 12.0 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 RLN97896.1 - 0.094 13.2 1.4 0.14 12.7 0.3 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 RLN97896.1 - 0.15 11.8 0.5 0.39 10.5 0.5 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 RLN97896.1 - 0.17 12.2 0.2 0.44 10.9 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 RLN97896.1 - 0.19 12.3 0.0 0.37 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 RLN97896.1 - 0.27 11.5 1.6 2.6 8.3 0.1 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Erf4 PF10256.9 RLN97897.1 - 1.9e-06 28.0 0.0 1.2e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family IBN_N PF03810.19 RLN97898.1 - 9.5e-08 31.8 0.3 6.4e-07 29.2 0.1 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain CRM1_C PF08767.11 RLN97898.1 - 0.0068 15.6 0.3 0.02 14.1 0.1 1.9 2 0 0 2 2 2 1 CRM1 C terminal DUF608 PF04685.13 RLN97898.1 - 0.15 11.2 0.2 0.26 10.4 0.2 1.3 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region MoCF_biosynth PF00994.24 RLN97899.1 - 3.2e-55 185.7 1.6 2.2e-28 98.7 0.5 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain eRF1_2 PF03464.15 RLN97899.1 - 1.6e-44 151.4 0.0 3.4e-44 150.4 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 2 MoeA_N PF03453.17 RLN97899.1 - 1.2e-41 142.1 6.5 2.5e-41 141.1 6.5 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) eRF1_3 PF03465.15 RLN97899.1 - 3e-35 121.1 0.0 1.1e-34 119.3 0.0 2.1 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 RLN97899.1 - 7.9e-19 67.9 0.0 1.6e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 RLN97899.1 - 2.7e-10 40.6 0.0 8.7e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 RLN97899.1 - 7.8e-10 39.1 0.0 2.3e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor MoeA_C PF03454.15 RLN97899.1 - 0.0002 21.5 0.0 0.00061 19.9 0.0 1.9 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) DBP10CT PF08147.12 RLN97899.1 - 0.17 12.1 0.0 0.57 10.5 0.0 1.8 1 0 0 1 1 1 0 DBP10CT (NUC160) domain AMP-binding PF00501.28 RLN97900.1 - 2.1e-85 286.9 0.0 2.7e-85 286.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN97900.1 - 1.2e-17 64.6 0.1 4e-17 63.0 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2148 PF09918.9 RLN97900.1 - 0.075 13.1 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) Patched PF02460.18 RLN97901.1 - 7.5e-14 50.8 10.6 1.5e-05 23.4 0.1 3.1 2 1 1 3 3 3 3 Patched family NPC1_N PF16414.5 RLN97901.1 - 5.9e-13 48.9 4.0 1.1e-12 48.1 4.0 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 RLN97901.1 - 9.2e-11 41.8 0.7 9.2e-11 41.8 0.7 3.1 2 1 1 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Rdx PF10262.9 RLN97902.1 - 6.4e-10 39.1 0.0 9.3e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Rdx family ZF-HD_dimer PF04770.12 RLN97902.1 - 0.012 15.9 0.2 0.018 15.4 0.2 1.3 1 0 0 1 1 1 0 ZF-HD protein dimerisation region RasGEF_N_2 PF14663.6 RLN97903.1 - 0.032 14.6 0.2 0.076 13.4 0.2 1.6 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain ThiF PF00899.21 RLN97903.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 ThiF family EF-hand_1 PF00036.32 RLN97904.1 - 2.7e-26 89.1 1.1 3.5e-07 29.3 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RLN97904.1 - 7.8e-26 90.3 0.2 1.2e-12 48.1 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair FKBP_C PF00254.28 RLN97904.1 - 2.1e-22 79.2 0.0 4.6e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_8 PF13833.6 RLN97904.1 - 3.7e-21 74.7 0.4 3.4e-10 39.6 0.0 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RLN97904.1 - 1.9e-20 71.0 1.5 0.00041 20.0 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RLN97904.1 - 1.2e-17 62.5 4.7 9e-05 21.8 0.1 4.6 4 0 0 4 4 4 4 EF hand WW PF00397.26 RLN97904.1 - 4.6e-05 23.4 0.0 8.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 WW domain SPARC_Ca_bdg PF10591.9 RLN97904.1 - 0.00029 21.1 1.1 0.59 10.5 0.0 2.7 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region DUF2058 PF09831.9 RLN97904.1 - 0.0094 16.1 2.0 0.023 14.9 1.5 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2058) FAM199X PF15814.5 RLN97905.1 - 0.0093 15.1 0.6 0.011 14.8 0.6 1.1 1 0 0 1 1 1 1 Protein family FAM199X NVEALA PF14055.6 RLN97905.1 - 0.02 14.9 1.7 0.037 14.0 0.7 1.9 2 0 0 2 2 2 0 NVEALA protein Trp_oprn_chp PF09534.10 RLN97905.1 - 0.039 13.8 4.9 0.053 13.3 4.9 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3824 PF12868.7 RLN97905.1 - 0.11 13.2 1.6 0.15 12.7 1.6 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) MULE PF10551.9 RLN97906.1 - 6e-10 39.4 0.0 1.4e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain zf-CCHC PF00098.23 RLN97906.1 - 0.066 13.3 2.3 0.22 11.7 2.3 2.0 1 0 0 1 1 1 0 Zinc knuckle SWIM PF04434.17 RLN97906.1 - 0.075 12.7 0.1 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 SWIM zinc finger IL10 PF00726.17 RLN97906.1 - 0.11 12.0 0.1 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 Interleukin 10 zf-CCHC_4 PF14392.6 RLN97906.1 - 0.23 11.2 3.0 0.25 11.1 1.2 1.9 2 0 0 2 2 2 0 Zinc knuckle AT_hook PF02178.19 RLN97906.1 - 0.44 10.6 2.4 1.1 9.4 2.4 1.7 1 0 0 1 1 1 0 AT hook motif Choline_kinase PF01633.20 RLN97909.1 - 7e-55 185.9 0.0 9.9e-55 185.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 RLN97909.1 - 2e-11 44.3 0.0 5.5e-11 42.8 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 RLN97909.1 - 0.0017 17.7 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Ank_4 PF13637.6 RLN97910.1 - 6.2e-08 33.0 1.7 3.5e-05 24.3 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN97910.1 - 1.5e-07 31.8 2.1 3.3e-07 30.8 2.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN97910.1 - 1.6e-07 31.5 7.3 9.3e-07 29.0 1.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN97910.1 - 4.5e-06 26.6 1.8 0.43 11.3 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 RLN97910.1 - 0.00054 20.3 3.9 0.92 10.1 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat DUF4407 PF14362.6 RLN97910.1 - 1.6 8.0 7.7 3.6 6.8 7.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L29 PF00831.23 RLN97914.1 - 0.019 14.9 0.7 0.07 13.1 0.7 2.0 1 0 0 1 1 1 0 Ribosomal L29 protein PriC PF07445.12 RLN97915.1 - 0.22 11.4 3.6 0.5 10.3 3.6 1.5 1 1 0 1 1 1 0 Primosomal replication protein priC B56 PF01603.20 RLN97916.1 - 2.2e-91 306.9 0.8 3.1e-91 306.4 0.8 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PH PF00169.29 RLN97916.1 - 2.5e-06 27.9 1.6 0.00013 22.4 0.2 2.6 1 1 1 2 2 2 2 PH domain PH_11 PF15413.6 RLN97916.1 - 0.031 14.7 0.0 0.08 13.4 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain TMEM219 PF14940.6 RLN97916.1 - 0.055 13.0 0.1 0.095 12.3 0.1 1.3 1 0 0 1 1 1 0 Transmembrane 219 TGase_elicitor PF16683.5 RLN97919.1 - 4.8e-164 545.4 0.4 5.7e-164 545.1 0.4 1.1 1 0 0 1 1 1 1 Transglutaminase elicitor MtN3_slv PF03083.16 RLN97921.1 - 6.8e-30 103.0 6.4 1.1e-21 76.6 0.3 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange 2HCT PF03390.15 RLN97921.1 - 0.00083 18.1 1.5 0.001 17.8 0.6 1.4 1 1 0 1 1 1 1 2-hydroxycarboxylate transporter family DUF1129 PF06570.11 RLN97921.1 - 0.08 12.4 3.5 0.1 12.1 2.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) B12D PF06522.11 RLN97921.1 - 1.1 9.1 4.4 29 4.5 0.1 3.2 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit MARVEL PF01284.23 RLN97921.1 - 4.2 7.4 10.8 18 5.4 10.5 2.0 1 1 0 1 1 1 0 Membrane-associating domain Ribosomal_S4e PF00900.20 RLN97922.1 - 1.1e-28 98.9 0.5 2.1e-28 98.0 0.5 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 RLN97922.1 - 1e-22 79.5 0.0 1.8e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus KOW PF00467.29 RLN97922.1 - 0.001 18.9 0.2 0.001 18.9 0.2 2.9 3 0 0 3 3 3 1 KOW motif RNA_pol_Rpb5_C PF01191.19 RLN97922.1 - 0.028 14.3 1.0 2.3 8.1 0.2 2.4 1 1 1 2 2 2 0 RNA polymerase Rpb5, C-terminal domain Sipho_tail PF05709.11 RLN97922.1 - 0.049 13.0 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 Phage tail protein Pro_isomerase PF00160.21 RLN97923.1 - 1.8e-18 67.3 0.0 1.8e-18 67.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNA_pol_A_bac PF01000.26 RLN97924.1 - 1.7e-30 105.6 0.0 3e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 RLN97924.1 - 2.9e-24 84.3 0.0 5.6e-24 83.4 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.6 RLN97924.1 - 0.027 14.3 0.2 13 5.7 0.0 3.3 4 0 0 4 4 4 0 RNA polymerase Rpb3/Rpb11 dimerisation domain HTH_Tnp_Tc5 PF03221.16 RLN97925.1 - 0.00045 20.2 0.0 0.00091 19.2 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF1389 PF07146.11 RLN97925.1 - 0.017 14.4 0.7 0.021 14.1 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1389) Mito_carr PF00153.27 RLN97926.1 - 3.6e-60 199.9 27.0 1.7e-18 66.3 0.1 6.8 6 2 0 6 6 6 6 Mitochondrial carrier protein DUF4514 PF14986.6 RLN97926.1 - 0.0085 16.0 0.3 7.9 6.5 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4514) SatD PF16264.5 RLN97926.1 - 0.016 14.8 0.0 0.79 9.3 0.0 2.2 2 0 0 2 2 2 0 SatD family (SatD) Carb_kinase PF01256.17 RLN97926.1 - 0.064 12.7 1.0 4.1 6.8 0.1 2.4 2 0 0 2 2 2 0 Carbohydrate kinase Parecho_VpG PF06344.11 RLN97926.1 - 1.9 9.3 4.2 1.6e+02 3.3 0.1 4.3 3 0 0 3 3 3 0 Parechovirus Genome-linked protein zf-CCCH_4 PF18044.1 RLN97926.1 - 4.7 7.1 5.1 41 4.1 0.4 2.6 2 0 0 2 2 2 0 CCCH-type zinc finger NUDIX PF00293.28 RLN97928.1 - 1.9e-19 70.0 0.0 2.9e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Pam16 PF03656.13 RLN97929.1 - 6.7e-21 74.6 0.1 9.8e-21 74.1 0.1 1.2 1 0 0 1 1 1 1 Pam16 EF-hand_8 PF13833.6 RLN97929.1 - 0.00012 21.8 0.8 0.00078 19.2 0.3 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN97929.1 - 0.00076 18.9 0.5 0.0088 15.5 0.1 2.7 3 0 0 3 3 3 1 EF hand AzlD PF05437.12 RLN97929.1 - 0.025 14.7 0.1 0.04 14.1 0.1 1.2 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) EF-hand_7 PF13499.6 RLN97929.1 - 0.034 14.6 1.2 0.24 11.9 0.2 2.8 3 0 0 3 3 3 0 EF-hand domain pair RRP14 PF15459.6 RLN97930.1 - 0.0074 16.9 1.6 0.014 16.0 1.6 1.5 1 0 0 1 1 1 1 60S ribosome biogenesis protein Rrp14 Kei1 PF08552.11 RLN97930.1 - 0.28 11.0 1.5 0.34 10.8 1.5 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Cytochrom_C1 PF02167.15 RLN97931.1 - 6.5e-91 303.9 0.0 7.8e-91 303.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 RLN97931.1 - 0.00083 19.6 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 RLN97931.1 - 0.046 14.9 0.1 0.097 13.8 0.1 1.7 1 1 0 1 1 1 0 Cytochrome c DUF1242 PF06842.12 RLN97932.1 - 8.5e-18 63.9 1.8 1.2e-17 63.3 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) HECT PF00632.25 RLN97933.1 - 2e-69 234.5 0.0 2.5e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) 60KD_IMP PF02096.20 RLN97934.1 - 7.6e-26 91.0 2.8 1.4e-25 90.1 2.8 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein TPR_1 PF00515.28 RLN97935.1 - 3.3e-20 71.0 0.1 6.2e-05 22.6 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN97935.1 - 1.2e-12 46.8 0.3 0.0012 18.8 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN97935.1 - 1.9e-08 33.9 0.0 0.072 13.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN97935.1 - 2.5e-08 33.5 0.1 1.8e-05 24.4 0.1 2.8 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 RLN97935.1 - 3.6e-08 33.9 2.1 1.2e-05 25.9 0.1 2.7 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 RLN97935.1 - 6.4e-08 32.5 1.1 0.005 17.1 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN97935.1 - 3.1e-06 27.3 0.2 0.0053 16.9 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN97935.1 - 0.00039 20.9 0.1 0.0014 19.1 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN97935.1 - 0.00057 19.7 0.2 0.39 10.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat RPAP3_C PF13877.6 RLN97935.1 - 0.0015 19.1 0.0 0.0027 18.2 0.0 1.5 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_12 PF13424.6 RLN97935.1 - 0.0035 17.6 0.9 0.59 10.5 0.2 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN97935.1 - 0.0053 17.5 0.3 9.6 7.3 0.0 3.7 1 1 3 4 4 4 1 Tetratricopeptide repeat Tetrabrachion PF11401.8 RLN97935.1 - 0.05 13.6 0.0 0.086 12.9 0.0 1.3 1 0 0 1 1 1 0 Tetrabrachion Fis1_TPR_C PF14853.6 RLN97935.1 - 0.094 12.8 1.2 4.3 7.5 0.1 2.9 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 RLN97935.1 - 0.31 11.8 2.1 8.3 7.3 0.0 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat HECT PF00632.25 RLN97936.1 - 2.1e-68 231.1 0.0 3.1e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 RLN97936.1 - 0.28 10.5 0.8 0.57 9.6 0.8 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Bromodomain PF00439.25 RLN97937.1 - 3.2e-14 52.8 0.0 7.2e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 RLN97937.1 - 8.9e-06 25.5 5.2 8.9e-06 25.5 5.2 3.3 3 1 0 3 3 3 1 PHD-finger Pkinase PF00069.25 RLN97939.1 - 2.2e-38 132.1 1.3 2.6e-22 79.5 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97939.1 - 1.7e-18 66.9 0.0 1.4e-12 47.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase RWD PF05773.22 RLN97939.1 - 5.8e-11 42.7 0.2 6.1e-09 36.2 0.0 3.1 2 1 0 2 2 2 1 RWD domain Kinase-like PF14531.6 RLN97939.1 - 0.0012 18.2 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 RLN97939.1 - 0.003 17.2 2.8 0.041 13.5 0.0 2.7 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RLN97939.1 - 0.0036 17.3 0.6 0.012 15.6 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 RLN97939.1 - 0.15 11.1 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Tub_N PF16322.5 RLN97939.1 - 5.8 7.3 17.4 0.084 13.3 8.3 2.1 2 0 0 2 2 2 0 Tubby N-terminal Enolase_C PF00113.22 RLN97940.1 - 1e-122 409.0 2.0 1.2e-122 408.8 2.0 1.0 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain MR_MLE_C PF13378.6 RLN97940.1 - 2.5e-09 37.0 0.0 5.8e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 RLN97940.1 - 4.4e-06 26.0 0.2 7.5e-06 25.3 0.2 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Enolase_N PF03952.16 RLN97941.1 - 3e-37 127.7 0.1 3.6e-37 127.5 0.1 1.0 1 0 0 1 1 1 1 Enolase, N-terminal domain TMF_TATA_bd PF12325.8 RLN97942.1 - 8.4e-10 38.9 4.5 8.4e-10 38.9 4.5 1.7 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding Pkinase_Tyr PF07714.17 RLN97943.1 - 1.2e-43 149.2 0.0 2e-43 148.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN97943.1 - 6.1e-38 130.7 0.0 2e-37 129.0 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.23 RLN97943.1 - 5.3e-19 67.6 2.7 1.4e-05 24.9 0.0 8.2 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN97943.1 - 6.6e-06 26.4 14.9 0.0074 16.7 0.8 5.5 4 2 2 6 6 6 4 HEAT repeats HEAT PF02985.22 RLN97943.1 - 0.00043 20.3 0.6 10 6.7 0.0 5.2 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 RLN97943.1 - 0.0024 18.3 10.3 0.011 16.2 0.3 5.1 5 1 1 6 6 6 2 HEAT-like repeat Atx10homo_assoc PF09759.9 RLN97943.1 - 0.012 15.6 0.0 14 5.8 0.0 3.6 3 1 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Pkinase_fungal PF17667.1 RLN97943.1 - 0.038 12.8 0.1 0.081 11.7 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Ank_2 PF12796.7 RLN97944.1 - 1.4e-75 249.9 11.5 3.6e-12 46.7 0.1 6.2 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN97944.1 - 3.8e-64 212.3 0.2 9e-10 38.9 0.0 8.0 4 3 4 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN97944.1 - 4.6e-53 176.6 15.2 1.8e-07 31.3 0.0 11.3 2 1 10 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 RLN97944.1 - 8.3e-53 174.6 9.7 0.00054 20.3 0.0 11.5 11 0 0 11 11 11 11 Ankyrin repeat Ank_3 PF13606.6 RLN97944.1 - 1.2e-50 163.5 4.3 0.008 16.6 0.0 12.7 13 0 0 13 13 13 12 Ankyrin repeat SIP PF04954.13 RLN97944.1 - 0.00021 21.8 0.6 0.75 10.3 0.0 4.2 1 1 1 3 3 3 2 Siderophore-interacting protein ArsP_1 PF03773.13 RLN97944.1 - 0.046 12.9 7.9 3.7 6.6 0.1 4.1 5 0 0 5 5 5 0 Predicted permease DUF4926 PF16277.5 RLN97944.1 - 0.083 12.3 0.0 6.4 6.2 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4926) PK_C PF02887.16 RLN97944.1 - 1.7 8.9 8.6 76 3.6 0.0 4.9 5 0 0 5 5 5 0 Pyruvate kinase, alpha/beta domain UBA PF00627.31 RLN97944.1 - 4.4 7.3 11.4 51 3.9 0.0 5.4 5 0 0 5 5 5 0 UBA/TS-N domain Biotin_carb_N PF00289.22 RLN97945.1 - 1.4e-45 154.4 0.1 1.8e-45 154.0 0.1 1.1 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain CoA_binding_3 PF13727.6 RLN97945.1 - 0.07 13.1 0.0 0.097 12.7 0.0 1.2 1 0 0 1 1 1 0 CoA-binding domain Sugar_tr PF00083.24 RLN97946.1 - 6.6e-36 124.1 10.5 7.5e-36 124.0 10.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN97946.1 - 1.2e-14 54.1 13.8 1.2e-14 54.1 13.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4131 PF13567.6 RLN97946.1 - 1.8 8.2 3.8 4.5 6.9 2.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Bromodomain PF00439.25 RLN97947.1 - 8.9e-18 64.2 0.1 2.8e-17 62.5 0.0 1.9 2 0 0 2 2 2 1 Bromodomain WSD PF15613.6 RLN97947.1 - 2.5e-14 53.5 0.8 6.9e-13 48.9 0.2 3.3 2 1 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Auxin_resp PF06507.13 RLN97947.1 - 0.0052 17.0 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Auxin response factor 7tm_1 PF00001.21 RLN97948.1 - 7.3 5.8 14.2 5.9 6.1 12.7 1.6 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) zf-ZPR1 PF03367.13 RLN97950.1 - 2.3e-99 329.8 0.0 4.9e-50 169.5 0.0 3.2 3 0 0 3 3 3 3 ZPR1 zinc-finger domain Corazonin PF17308.2 RLN97951.1 - 3.6 8.0 9.4 3.1 8.2 1.2 3.8 3 1 1 4 4 4 0 Pro-corazonin RNB PF00773.19 RLN97952.1 - 1.7e-85 287.3 0.0 2.6e-85 286.7 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 RLN97952.1 - 2.9e-15 56.0 0.0 7.3e-15 54.8 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 RLN97952.1 - 1.2e-06 28.3 0.0 2.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 RLN97952.1 - 0.051 13.5 0.0 0.41 10.6 0.0 2.5 2 1 0 2 2 2 0 S1 domain Kinesin PF00225.23 RLN97953.1 - 9.2e-54 182.6 0.0 1.9e-43 148.7 0.0 2.3 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 RLN97953.1 - 2.3e-18 66.6 0.0 1.3e-17 64.2 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding HHH_3 PF12836.7 RLN97953.1 - 0.019 15.2 0.0 0.051 13.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 RLN97953.1 - 0.1 13.2 0.0 0.99 10.1 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain Pkinase PF00069.25 RLN97954.1 - 2.9e-44 151.4 0.0 4.1e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.32 RLN97954.1 - 7.5e-27 90.8 6.1 1.2e-08 33.9 0.4 4.8 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RLN97954.1 - 5.2e-26 90.9 0.5 4.4e-12 46.3 0.0 3.1 3 1 0 3 3 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN97954.1 - 2.6e-22 76.8 6.1 2.3e-05 23.9 0.0 5.5 5 1 1 6 6 6 4 EF-hand domain EF-hand_8 PF13833.6 RLN97954.1 - 1.6e-20 72.7 8.4 2.5e-10 40.1 0.8 3.4 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 RLN97954.1 - 3.7e-17 61.0 3.6 3e-05 23.3 0.4 4.5 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.17 RLN97954.1 - 2.1e-13 50.2 0.0 3.1e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_9 PF14658.6 RLN97954.1 - 1.7e-07 31.4 0.4 0.013 15.8 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain Kdo PF06293.14 RLN97954.1 - 8.6e-07 28.5 0.3 2.1e-05 24.0 0.4 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.7 RLN97954.1 - 0.0001 22.2 1.0 0.2 11.6 0.2 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RLN97954.1 - 0.00037 20.8 0.0 1.1 9.6 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.23 RLN97954.1 - 0.00064 19.7 0.1 0.0011 18.9 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 RLN97954.1 - 0.0046 16.6 0.3 0.013 15.1 0.2 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Dockerin_1 PF00404.18 RLN97954.1 - 0.011 15.9 5.5 1.1 9.5 3.0 3.5 1 1 1 2 2 2 0 Dockerin type I domain Caleosin PF05042.13 RLN97954.1 - 0.03 14.3 0.1 2 8.3 0.0 2.6 2 1 0 2 2 2 0 Caleosin related protein Kinase-like PF14531.6 RLN97954.1 - 0.085 12.2 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Kinase-like DUF1103 PF06513.11 RLN97954.1 - 0.11 12.1 0.5 0.16 11.6 0.5 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) Herpes_UL7 PF01677.16 RLN97955.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL7 like Macoilin PF09726.9 RLN97956.1 - 0.15 10.5 4.0 0.18 10.4 4.0 1.0 1 0 0 1 1 1 0 Macoilin family PQ-loop PF04193.14 RLN97957.1 - 5.8e-11 42.0 0.6 9.5e-11 41.3 0.6 1.4 1 0 0 1 1 1 1 PQ loop repeat DUF4010 PF13194.6 RLN97957.1 - 0.0026 17.5 0.2 0.0032 17.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4010) ER_lumen_recept PF00810.18 RLN97957.1 - 0.014 16.3 0.1 0.033 15.0 0.1 1.6 2 0 0 2 2 2 0 ER lumen protein retaining receptor DUF2070 PF09843.9 RLN97957.1 - 0.091 11.0 0.1 0.1 10.9 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) LCM PF04072.14 RLN97958.1 - 8.1e-40 136.8 0.0 1.3e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase PQ-loop PF04193.14 RLN97958.1 - 1.7e-10 40.5 1.6 3.1e-10 39.7 1.6 1.4 1 0 0 1 1 1 1 PQ loop repeat MtN3_slv PF03083.16 RLN97958.1 - 0.013 15.5 0.9 0.022 14.8 0.9 1.4 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RLN97959.1 - 1.9e-12 46.8 0.7 1.9e-12 46.8 0.7 1.6 2 0 0 2 2 2 1 PQ loop repeat MtN3_slv PF03083.16 RLN97959.1 - 0.0075 16.3 1.0 0.01 15.9 1.0 1.3 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange SIR2 PF02146.17 RLN97962.1 - 1.5e-53 181.3 0.0 2.6e-53 180.6 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 RLN97962.1 - 1.2e-05 25.1 0.1 0.067 12.9 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Methyltransf_16 PF10294.9 RLN97963.1 - 2.8e-07 30.4 0.0 3.8e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase V_ATPase_I PF01496.19 RLN97964.1 - 2.6e-57 194.4 0.0 3e-57 194.2 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Myb_DNA-binding PF00249.31 RLN97965.1 - 1.5e-09 37.8 0.1 2.7e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN97965.1 - 0.0062 16.8 0.0 0.026 14.8 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Hamartin PF04388.12 RLN97965.1 - 7.1 5.2 13.8 12 4.4 13.8 1.5 1 0 0 1 1 1 0 Hamartin protein p450 PF00067.22 RLN97966.1 - 8.3e-15 54.5 0.1 8.7e-15 54.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 NMO PF03060.15 RLN97967.1 - 2.4e-65 221.1 0.4 5.2e-65 220.0 0.4 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 RLN97967.1 - 8.7e-13 48.0 0.1 2.8e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 RLN97967.1 - 1.6e-05 24.1 0.5 3.9e-05 22.9 0.5 1.6 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 RLN97967.1 - 0.00049 19.4 0.2 0.00083 18.6 0.2 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 RLN97967.1 - 0.00087 18.8 0.2 0.0017 17.8 0.2 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF561 PF04481.12 RLN97967.1 - 0.044 12.9 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF561) ThiG PF05690.14 RLN97967.1 - 0.049 12.9 1.7 0.1 11.9 1.7 1.5 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG DEP PF00610.21 RLN97968.1 - 7e-20 70.9 0.2 3.8e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) B_solenoid_ydck PF18836.1 RLN97968.1 - 0.066 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Beta solenoid repeat from YDCK BUD22 PF09073.10 RLN97968.1 - 0.13 11.6 11.3 0.23 10.8 11.3 1.3 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 RLN97968.1 - 3 6.5 5.6 4.5 5.9 5.6 1.2 1 0 0 1 1 1 0 Presenilin AATF-Che1 PF13339.6 RLN97968.1 - 9.6 6.9 13.5 4.7 7.9 10.2 2.1 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Sugar_tr PF00083.24 RLN97969.1 - 8.6e-37 127.1 25.7 8.2e-36 123.8 25.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN97969.1 - 1.5e-32 112.9 25.5 1.5e-32 112.9 25.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TolA_bind_tri PF16331.5 RLN97971.1 - 0.051 13.7 1.8 0.11 12.6 1.8 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation SKA2 PF16740.5 RLN97971.1 - 0.084 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 DivIC PF04977.15 RLN97971.1 - 0.26 11.1 1.7 0.95 9.3 0.9 2.2 2 0 0 2 2 2 0 Septum formation initiator FSH1 PF03959.13 RLN97972.1 - 9.5e-33 113.6 0.0 1.3e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) FSH1 PF03959.13 RLN97973.1 - 7.7e-34 117.2 0.0 9.3e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Kinesin PF00225.23 RLN97974.1 - 2.3e-43 148.4 0.1 2.3e-43 148.4 0.1 2.9 3 0 0 3 3 3 1 Kinesin motor domain UCH PF00443.29 RLN97975.1 - 2.8e-55 187.6 0.0 4.6e-55 186.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RLN97975.1 - 8.1e-29 101.2 0.1 2.7e-28 99.5 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 RLN97975.1 - 0.00034 20.3 0.2 0.0079 15.9 0.0 2.8 2 0 0 2 2 2 1 Ubiquitin family UN_NPL4 PF11543.8 RLN97975.1 - 0.029 14.9 0.3 3.6 8.1 0.0 3.3 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 Ubiquitin_2 PF14560.6 RLN97975.1 - 0.081 13.4 0.1 0.46 11.0 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain USP7_C2 PF14533.6 RLN97975.1 - 0.52 10.0 5.4 2.6 7.7 0.3 3.1 3 1 0 3 3 3 0 Ubiquitin-specific protease C-terminal RXT2_N PF08595.11 RLN97975.1 - 1.4 8.9 7.9 1.1 9.2 1.9 2.8 2 0 0 2 2 2 0 RXT2-like, N-terminal Slu7 PF11708.8 RLN97975.1 - 1.7 8.3 13.0 2 8.1 2.7 3.2 3 0 0 3 3 3 0 Pre-mRNA splicing Prp18-interacting factor Astro_capsid_p PF12226.8 RLN97975.1 - 3 6.9 7.8 0.15 11.2 1.4 2.0 2 0 0 2 2 2 0 Turkey astrovirus capsid protein PPP4R2 PF09184.11 RLN97975.1 - 8.5 5.9 14.0 0.37 10.3 2.1 2.6 2 0 0 2 2 2 0 PPP4R2 eIF-3_zeta PF05091.12 RLN97976.1 - 3.8e-18 65.8 0.2 5e-18 65.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Arm PF00514.23 RLN97977.1 - 5.8e-40 134.1 21.2 9e-05 22.4 0.0 13.1 13 0 0 13 13 13 8 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 RLN97977.1 - 1e-08 35.0 0.0 0.59 9.5 0.1 5.6 4 2 1 5 5 5 4 Armadillo-like Atx10homo_assoc PF09759.9 RLN97977.1 - 1.6e-08 34.4 1.2 0.073 13.1 0.1 5.4 4 1 1 5 5 5 2 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.8 RLN97977.1 - 1.2e-07 31.8 0.1 0.35 10.8 0.0 5.3 6 1 0 6 6 6 2 Myosin-binding striated muscle assembly central Acyl-CoA_dh_N PF02771.16 RLN97977.1 - 1.5e-07 32.0 6.4 29 5.4 0.1 9.6 8 3 1 9 9 9 0 Acyl-CoA dehydrogenase, N-terminal domain Arylsulfotran_N PF17425.2 RLN97977.1 - 1.3e-05 25.2 0.0 97 3.1 0.0 7.7 9 0 0 9 9 9 0 Arylsulfotransferase Ig-like domain FERM_F1 PF18379.1 RLN97977.1 - 2.6e-05 24.1 0.4 6.9 6.8 0.0 6.8 1 1 7 9 9 9 1 FERM F1 ubiquitin-like domain DUF1654 PF07867.11 RLN97977.1 - 9.4e-05 22.1 0.8 5.9 6.7 0.0 6.3 3 2 5 8 8 8 1 Protein of unknown function (DUF1654) HEAT_2 PF13646.6 RLN97977.1 - 0.00024 21.5 30.4 0.45 10.9 1.4 6.7 4 1 4 8 8 8 5 HEAT repeats HEAT PF02985.22 RLN97977.1 - 0.00091 19.3 19.2 14 6.2 0.0 10.1 13 0 0 13 13 11 0 HEAT repeat HEAT_EZ PF13513.6 RLN97977.1 - 0.0045 17.5 29.9 0.74 10.4 0.3 8.9 6 3 5 11 11 10 3 HEAT-like repeat Pico_P2B PF01552.17 RLN97977.1 - 0.027 14.6 0.0 3.4e+02 1.5 0.0 5.7 7 1 1 8 8 8 0 Picornavirus 2B protein Succ_CoA_lig PF13607.6 RLN97977.1 - 0.086 12.6 6.7 6.1 6.6 0.0 5.0 4 3 1 6 6 6 0 Succinyl-CoA ligase like flavodoxin domain RPAP1_C PF08620.10 RLN97977.1 - 0.58 10.3 2.3 64 3.8 0.0 4.8 5 0 0 5 5 5 0 RPAP1-like, C-terminal FSH1 PF03959.13 RLN97978.1 - 8.9e-96 319.6 0.0 3.6e-37 128.1 0.0 4.1 2 1 1 3 3 3 3 Serine hydrolase (FSH1) DUF2238 PF09997.9 RLN97978.1 - 1.6e-05 24.8 1.0 0.69 9.7 0.0 3.4 3 0 0 3 3 3 2 Predicted membrane protein (DUF2238) Abhydrolase_2 PF02230.16 RLN97978.1 - 0.00027 20.8 0.0 5.2 6.8 0.0 3.6 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 RLN97978.1 - 0.005 16.7 0.0 3.5 7.5 0.0 3.2 3 0 0 3 3 3 1 Lipase (class 3) Palm_thioest PF02089.15 RLN97978.1 - 0.024 14.5 0.0 33 4.2 0.0 3.3 3 0 0 3 3 3 0 Palmitoyl protein thioesterase DUF3089 PF11288.8 RLN97978.1 - 0.026 14.1 0.0 26 4.3 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3089) PAP2 PF01569.21 RLN97978.1 - 0.044 13.6 5.6 6.3 6.6 0.2 3.7 4 0 0 4 4 4 0 PAP2 superfamily PE-PPE PF08237.11 RLN97978.1 - 0.12 11.9 0.0 39 3.7 0.0 3.1 3 0 0 3 3 3 0 PE-PPE domain FecCD PF01032.18 RLN97978.1 - 0.21 10.6 1.2 9.7 5.1 0.1 2.2 2 0 0 2 2 2 0 FecCD transport family TFIIA PF03153.13 RLN97979.1 - 0.42 10.6 12.8 0.51 10.3 12.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MCD_N PF17408.2 RLN97979.1 - 1.1 9.5 12.5 0.23 11.6 2.2 2.6 1 1 1 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain FSH1 PF03959.13 RLN97980.1 - 1.8e-35 122.5 0.0 2.5e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) FSH1 PF03959.13 RLN97981.1 - 2.5e-34 118.8 0.0 3.3e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 RLN97981.1 - 0.0076 16.1 0.0 0.017 14.9 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 RLN97982.1 - 7.5e-34 117.2 0.0 1e-33 116.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Palm_thioest PF02089.15 RLN97982.1 - 0.062 13.1 0.0 0.098 12.5 0.0 1.4 1 1 0 1 1 1 0 Palmitoyl protein thioesterase DDE_Tnp_ISL3 PF01610.17 RLN97983.1 - 0.025 14.3 0.0 0.058 13.1 0.0 1.7 2 0 0 2 2 2 0 Transposase DDE_Tnp_ISL3 PF01610.17 RLN97984.1 - 0.0076 16.0 0.2 0.031 14.0 0.1 1.8 1 1 1 2 2 2 1 Transposase MULE PF10551.9 RLN97984.1 - 0.019 15.4 0.0 0.053 13.9 0.0 1.8 2 0 0 2 2 2 0 MULE transposase domain GMC_oxred_C PF05199.13 RLN97986.1 - 1.2e-22 81.0 0.0 1.3e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Aldedh PF00171.22 RLN97987.1 - 2.1e-142 474.9 0.1 2.6e-142 474.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 RLN97987.1 - 0.0024 17.4 0.0 0.011 15.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) ABC2_membrane PF01061.24 RLN97988.1 - 2e-27 96.0 31.7 2e-27 96.0 31.7 1.3 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 RLN97988.1 - 4.2e-08 33.0 0.0 4.2e-08 33.0 0.0 2.4 3 0 0 3 3 3 1 CDR ABC transporter DUF3930 PF13067.6 RLN97988.1 - 2.8 8.2 6.1 1 9.7 0.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3930) Drc1-Sld2 PF11719.8 RLN97990.1 - 0.0062 16.1 0.7 0.01 15.4 0.7 1.3 1 0 0 1 1 1 1 DNA replication and checkpoint protein CENP-B_dimeris PF09026.10 RLN97990.1 - 0.013 15.9 3.2 0.013 15.9 3.2 2.4 1 1 1 2 2 2 0 Centromere protein B dimerisation domain Nop14 PF04147.12 RLN97990.1 - 0.19 9.9 8.7 0.25 9.5 8.7 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 RLN97990.1 - 0.95 8.6 3.0 1.6 7.9 3.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 RLN97990.1 - 4 6.7 10.0 6.4 6.0 10.0 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 RLN97990.1 - 5.3 5.0 11.8 7.3 4.5 11.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi PH PF00169.29 RLN97991.1 - 1.9e-12 47.6 0.0 3.6e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN97991.1 - 0.0032 17.7 0.0 0.0063 16.8 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 RLN97991.1 - 0.0033 17.5 0.0 0.049 13.8 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 RLN97991.1 - 0.053 13.9 0.3 0.26 11.7 0.3 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain PI3_PI4_kinase PF00454.27 RLN97992.1 - 8.6e-75 251.8 0.0 1.3e-74 251.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 RLN97992.1 - 2.2e-35 121.0 1.1 5.3e-35 119.8 1.1 1.7 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 RLN97992.1 - 3.2e-17 62.0 0.2 8.2e-17 60.7 0.2 1.8 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 RLN97992.1 - 0.0011 18.3 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 FAT domain NOC3p PF07540.11 RLN97993.1 - 1.5e-23 83.0 0.5 4.8e-23 81.4 0.1 2.1 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 RLN97993.1 - 4.1e-22 79.0 3.8 4.7e-22 78.8 0.3 2.5 2 0 0 2 2 2 1 CBF/Mak21 family DUF2847 PF11009.8 RLN97993.1 - 0.12 12.3 0.1 0.41 10.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) RRN3 PF05327.11 RLN97993.1 - 2.1 6.8 13.2 1.2 7.6 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Pkinase PF00069.25 RLN97994.1 - 7.8e-65 218.9 0.0 1e-64 218.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN97994.1 - 7.8e-29 100.7 0.0 1.2e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 RLN97994.1 - 0.019 15.7 0.1 0.29 11.9 0.2 2.6 2 1 0 2 2 2 0 Protein kinase C terminal domain FYVE_2 PF02318.16 RLN97997.1 - 0.00092 19.4 7.3 0.00092 19.4 7.3 2.3 1 1 1 2 2 2 1 FYVE-type zinc finger FYVE PF01363.21 RLN97997.1 - 0.0018 18.3 8.9 0.0042 17.2 8.9 1.6 1 0 0 1 1 1 1 FYVE zinc finger Caskin1-CID PF16600.5 RLN97997.1 - 0.52 10.9 2.9 1.6 9.4 2.9 1.8 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain FYVE PF01363.21 RLN97998.1 - 0.00014 21.9 12.0 0.00036 20.6 12.0 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN97998.1 - 0.0017 18.6 11.5 0.0044 17.2 11.5 1.6 1 1 0 1 1 1 1 FYVE-type zinc finger DUF460 PF04312.13 RLN97999.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF460) OPA3 PF07047.12 RLN98001.1 - 9.5e-33 112.6 0.1 1.7e-32 111.8 0.1 1.4 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) RhoGAP PF00620.27 RLN98004.1 - 0.058 13.2 0.0 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 RhoGAP domain TCR PF03638.15 RLN98005.1 - 0.011 16.1 17.3 0.011 16.1 17.3 3.2 2 1 0 2 2 2 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain tRNA-synt_2c PF01411.19 RLN98006.1 - 2.2e-155 518.3 0.0 3.3e-155 517.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 RLN98006.1 - 5.2e-10 39.3 0.1 1e-09 38.3 0.1 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 RLN98006.1 - 8e-07 29.6 0.3 1.7e-05 25.2 0.2 2.6 2 0 0 2 2 2 1 DHHA1 domain zf-BED PF02892.15 RLN98007.1 - 0.00011 22.2 0.2 0.0002 21.3 0.2 1.4 1 0 0 1 1 1 1 BED zinc finger Fz PF01392.22 RLN98008.1 - 0.0019 18.8 0.2 0.0046 17.6 0.2 1.7 1 1 0 1 1 1 1 Fz domain Mid1 PF12929.7 RLN98008.1 - 0.0068 15.7 0.2 0.0073 15.6 0.2 1.2 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component TPR_1 PF00515.28 RLN98009.1 - 5.5e-29 98.8 20.6 1.1e-06 28.2 0.0 6.8 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 RLN98009.1 - 1.9e-24 83.8 17.3 0.00013 21.9 0.0 8.1 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 RLN98009.1 - 1.5e-23 80.9 22.8 0.0004 20.3 0.0 8.6 8 0 0 8 8 8 6 Tetratricopeptide repeat ANAPC8 PF04049.13 RLN98009.1 - 6.1e-14 52.3 0.3 3.1e-13 50.0 0.1 2.3 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_11 PF13414.6 RLN98009.1 - 1.1e-12 47.4 15.0 1.8e-06 27.5 0.5 6.3 4 2 3 7 7 6 3 TPR repeat TPR_19 PF14559.6 RLN98009.1 - 3e-12 46.8 13.3 0.063 13.8 0.2 6.5 4 2 1 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 RLN98009.1 - 1.2e-11 45.1 36.2 3.6e-06 27.5 0.4 8.3 8 2 2 10 10 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN98009.1 - 1.7e-11 43.9 26.7 0.042 14.7 0.0 10.0 7 4 3 10 10 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 RLN98009.1 - 1.5e-09 38.0 24.9 9.6e-06 25.8 1.7 6.7 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 RLN98009.1 - 3.2e-09 36.2 17.8 0.022 14.8 0.2 6.9 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 RLN98009.1 - 1.1e-06 28.7 13.7 0.024 14.8 0.0 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 RLN98009.1 - 3.2e-05 24.0 15.1 1.5 9.3 0.1 7.8 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN98009.1 - 0.0002 21.1 15.4 0.93 9.5 0.1 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat ChAPs PF09295.10 RLN98009.1 - 0.0014 17.7 0.0 0.29 10.1 0.0 2.8 1 1 2 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.6 RLN98009.1 - 0.0025 17.9 1.0 0.21 11.7 0.3 3.3 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 RLN98009.1 - 0.0051 17.0 21.4 1.7 8.9 0.1 6.9 3 1 5 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_18 PF13512.6 RLN98009.1 - 0.04 14.0 0.6 7.9 6.6 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN98009.1 - 0.042 14.5 24.0 3.3 8.6 0.2 8.3 9 2 0 9 9 9 0 Tetratricopeptide repeat PPR PF01535.20 RLN98009.1 - 0.087 13.1 3.1 10 6.6 0.1 4.1 5 0 0 5 5 4 0 PPR repeat LRR_1 PF00560.33 RLN98010.1 - 0.02 15.4 1.3 27 5.8 0.0 4.5 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.6 RLN98010.1 - 0.34 10.7 3.1 0.47 10.2 0.4 2.8 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 RLN98010.1 - 6.3 7.4 6.4 2.1 8.9 0.1 3.3 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) HHH PF00633.23 RLN98011.1 - 0.00013 21.6 0.9 0.00026 20.7 0.2 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif Transposase_20 PF02371.16 RLN98011.1 - 0.029 14.7 0.1 0.062 13.6 0.1 1.6 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family HHH_5 PF14520.6 RLN98011.1 - 0.059 14.0 0.3 0.25 12.0 0.2 2.0 1 1 0 1 1 1 0 Helix-hairpin-helix domain HHH_3 PF12836.7 RLN98011.1 - 0.15 12.4 0.0 0.42 10.9 0.0 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif Nucleo_P87 PF07267.11 RLN98011.1 - 0.29 9.9 2.5 0.36 9.6 2.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 LRAT PF04970.13 RLN98012.1 - 4.3e-07 30.3 0.0 8.5e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 Lecithin retinol acyltransferase Aa_trans PF01490.18 RLN98013.1 - 5e-44 150.6 15.3 5.9e-44 150.4 15.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ADP_ribosyl_GH PF03747.14 RLN98013.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase ABC2_membrane_5 PF13346.6 RLN98013.1 - 0.34 10.4 10.7 0.073 12.6 2.0 2.5 2 0 0 2 2 2 0 ABC-2 family transporter protein Ank_2 PF12796.7 RLN98014.1 - 2.6e-14 53.5 0.2 1.8e-07 31.7 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN98014.1 - 1.4e-13 50.8 0.6 0.0017 18.7 0.0 3.7 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN98014.1 - 2.9e-11 42.5 0.5 0.042 14.4 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 RLN98014.1 - 1.7e-10 40.9 2.7 0.0052 17.2 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 RLN98014.1 - 5.8e-10 39.5 0.2 0.0022 18.5 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) FYVE PF01363.21 RLN98014.1 - 0.0002 21.4 7.9 0.00043 20.4 7.9 1.5 1 1 0 1 1 1 1 FYVE zinc finger Prok-RING_2 PF14445.6 RLN98014.1 - 0.00095 19.3 2.2 0.0025 17.9 2.2 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 2 DUF4428 PF14471.6 RLN98014.1 - 0.019 14.8 3.9 0.057 13.4 3.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) FYVE_2 PF02318.16 RLN98014.1 - 0.04 14.1 4.0 0.078 13.2 4.0 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Sar8_2 PF03058.14 RLN98014.1 - 0.95 10.0 4.9 44 4.7 4.9 2.7 1 1 0 1 1 1 0 Sar8.2 family PRIMA1 PF16101.5 RLN98015.1 - 1.4 9.0 10.1 3.3 7.8 10.1 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF3209 PF11483.8 RLN98017.1 - 0.014 15.9 1.7 0.014 15.9 1.7 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3209) GAS PF13851.6 RLN98017.1 - 0.042 13.2 38.8 0.014 14.8 21.6 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding MCU PF04678.13 RLN98017.1 - 0.26 11.4 25.3 0.42 10.7 4.5 2.6 2 1 0 2 2 2 0 Mitochondrial calcium uniporter TSC22 PF01166.18 RLN98017.1 - 1 9.7 10.8 0.93 9.9 0.8 3.6 3 0 0 3 3 3 0 TSC-22/dip/bun family GIT_CC PF16559.5 RLN98017.1 - 1.1 9.1 20.7 0.31 10.9 6.8 3.5 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1664 PF07889.12 RLN98017.1 - 5.1 7.2 15.3 0.25 11.4 4.1 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 RLN98017.1 - 9.3 4.0 21.3 1.2 6.9 8.3 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Prominin PF05478.11 RLN98017.1 - 9.5 4.0 13.5 0.45 8.4 4.5 2.1 2 0 0 2 2 2 0 Prominin Arf PF00025.21 RLN98019.1 - 1.8e-10 40.5 0.7 0.0012 18.4 0.1 3.1 3 0 0 3 3 3 2 ADP-ribosylation factor family G-alpha PF00503.20 RLN98019.1 - 0.0002 20.6 1.4 0.068 12.3 0.0 2.6 2 1 1 3 3 3 2 G-protein alpha subunit MMR_HSR1 PF01926.23 RLN98019.1 - 0.0016 18.5 0.0 0.0043 17.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Androgen_recep PF02166.16 RLN98019.1 - 0.0097 14.8 1.0 0.014 14.2 1.0 1.1 1 0 0 1 1 1 1 Androgen receptor AAA_29 PF13555.6 RLN98019.1 - 0.016 14.9 0.0 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 RLN98019.1 - 0.019 15.5 0.1 0.026 15.1 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 RLN98019.1 - 0.052 13.7 0.3 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RLN98019.1 - 0.063 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RLN98019.1 - 0.064 13.2 0.2 1.2 9.1 0.0 2.4 3 0 0 3 3 3 0 RsgA GTPase AAA_16 PF13191.6 RLN98019.1 - 0.098 13.0 0.9 0.26 11.7 0.9 2.0 1 1 0 1 1 1 0 AAA ATPase domain Agenet PF05641.12 RLN98022.1 - 0.00011 22.6 17.9 0.71 10.4 0.1 6.0 6 0 0 6 6 6 3 Agenet domain PilZ PF07238.14 RLN98022.1 - 0.015 15.6 0.6 68 3.8 0.0 4.1 3 0 0 3 3 3 0 PilZ domain Tudor_3 PF18115.1 RLN98022.1 - 0.016 15.0 0.4 0.32 10.9 0.1 2.7 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain zf-C2H2_jaz PF12171.8 RLN98023.1 - 0.00078 19.7 0.1 0.0017 18.6 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RLN98023.1 - 0.00092 19.5 0.2 0.0023 18.3 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Syntaxin-6_N PF09177.11 RLN98023.1 - 0.0016 19.0 0.3 0.0031 18.0 0.3 1.6 1 1 0 1 1 1 1 Syntaxin 6, N-terminal zf-C2H2_6 PF13912.6 RLN98023.1 - 0.0024 17.8 0.1 0.0056 16.7 0.1 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 RLN98023.1 - 0.0082 16.9 0.3 0.026 15.3 0.3 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 RLN98023.1 - 0.074 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 RLN98023.1 - 0.091 13.3 0.2 0.22 12.1 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 RLN98023.1 - 0.14 12.8 0.7 0.49 11.0 0.0 2.2 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_9 PF16293.5 RLN98023.1 - 0.16 11.8 0.1 0.45 10.4 0.0 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) CSRNP_N PF16019.5 RLN98024.1 - 0.011 15.6 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus PH PF00169.29 RLN98025.1 - 6.2e-15 55.6 0.0 1.3e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 RLN98025.1 - 0.02 15.2 0.5 0.11 12.9 0.5 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain PH_6 PF15406.6 RLN98025.1 - 0.022 15.0 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain PI3Ka PF00613.20 RLN98025.1 - 0.086 12.2 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) ABC_ATPase PF09818.9 RLN98026.1 - 6.3e-170 565.8 0.0 7.3e-170 565.6 0.0 1.0 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 RLN98026.1 - 0.02 15.4 0.0 0.034 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mannosyl_trans3 PF11051.8 RLN98028.1 - 1.2e-13 51.1 0.0 1.5e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative DUF1772 PF08592.11 RLN98028.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Peptidase_C48 PF02902.19 RLN98030.1 - 1.8e-12 47.6 0.1 4.7e-12 46.2 0.1 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MULE PF10551.9 RLN98030.1 - 0.00017 21.9 1.9 0.0091 16.4 0.3 3.3 3 0 0 3 3 3 1 MULE transposase domain DUF934 PF06073.12 RLN98030.1 - 0.0041 17.0 0.0 0.34 10.8 0.0 3.2 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF934) SnoaL_4 PF13577.6 RLN98030.1 - 0.26 11.4 2.4 1.5 8.9 0.1 2.6 2 1 0 2 2 2 0 SnoaL-like domain Glyco_hydro_47 PF01532.20 RLN98031.1 - 6.5e-110 368.2 0.0 5.4e-109 365.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 PA PF02225.22 RLN98031.1 - 4.7e-12 45.8 0.3 9.2e-12 44.8 0.3 1.5 1 0 0 1 1 1 1 PA domain Anoctamin PF04547.12 RLN98032.1 - 3e-110 369.2 0.4 2.2e-103 346.5 0.0 2.4 1 1 1 2 2 2 2 Calcium-activated chloride channel Anoct_dimer PF16178.5 RLN98032.1 - 1.2e-11 44.8 1.9 7.6e-11 42.2 1.9 2.1 1 1 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin RSN1_7TM PF02714.15 RLN98032.1 - 0.14 11.5 1.5 0.27 10.5 1.5 1.4 1 0 0 1 1 1 0 Calcium-dependent channel, 7TM region, putative phosphate FTR1 PF03239.14 RLN98032.1 - 0.28 10.3 2.5 0.44 9.7 2.5 1.2 1 0 0 1 1 1 0 Iron permease FTR1 family PhyH PF05721.13 RLN98033.1 - 1.9e-12 47.9 0.0 3e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DOT1 PF08123.13 RLN98034.1 - 0.0017 17.9 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Pkinase PF00069.25 RLN98035.1 - 3e-35 121.9 0.0 5.2e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 RLN98035.1 - 1.2e-31 108.6 0.0 2.1e-14 53.4 0.0 3.1 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain PP2C PF00481.21 RLN98035.1 - 5.9e-15 55.6 0.0 1.3e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase_Tyr PF07714.17 RLN98035.1 - 1e-13 51.2 0.0 2e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN98035.1 - 7.5e-09 35.3 0.0 1.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like WD40 PF00400.32 RLN98036.1 - 8e-05 23.3 0.0 2.9 8.9 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC_CDC26 PF10471.9 RLN98037.1 - 0.28 12.0 8.7 0.68 10.8 8.7 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Sugar_tr PF00083.24 RLN98038.1 - 1.8e-81 274.3 20.8 6.3e-81 272.5 20.8 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN98038.1 - 7.4e-17 61.3 38.6 7.1e-12 44.9 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3792 PF12670.7 RLN98038.1 - 0.0096 16.1 5.4 0.0096 16.1 5.4 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF3792) MFS_3 PF05977.13 RLN98038.1 - 0.015 13.7 7.1 0.31 9.4 3.0 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector PP2C PF00481.21 RLN98039.1 - 4.1e-16 59.4 0.0 6.6e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RLN98039.1 - 0.00033 20.3 0.0 0.0007 19.3 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C HyaE PF07449.11 RLN98039.1 - 0.08 12.9 0.0 0.62 10.1 0.0 2.4 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Galactosyl_T PF01762.21 RLN98039.1 - 0.085 12.7 0.1 0.27 11.0 0.1 1.8 1 1 0 1 1 1 0 Galactosyltransferase Asp PF00026.23 RLN98040.1 - 6.9e-76 255.7 0.1 8.2e-76 255.4 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RLN98040.1 - 3.5e-08 33.9 1.0 6.5e-06 26.5 0.0 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal MIP PF00230.20 RLN98041.1 - 1e-14 54.8 2.2 1.1e-14 54.7 2.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein Phage_holin_5_2 PF16079.5 RLN98041.1 - 0.22 11.9 0.9 0.44 10.9 0.1 1.9 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V zf-RING_2 PF13639.6 RLN98042.1 - 6e-11 42.5 5.4 1.1e-10 41.7 5.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 RLN98042.1 - 1.5e-07 31.0 3.8 2.9e-07 30.1 3.8 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RLN98042.1 - 3.5e-07 29.9 6.1 6.8e-07 29.0 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN98042.1 - 3.8e-07 30.3 4.9 7.5e-07 29.4 4.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RLN98042.1 - 8.4e-06 25.7 5.8 1.4e-05 24.9 5.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RLN98042.1 - 1.3e-05 25.2 0.6 0.00012 22.0 1.1 2.2 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 RLN98042.1 - 8.6e-05 22.3 7.2 0.00016 21.5 7.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 RLN98042.1 - 0.00011 22.0 4.9 0.0002 21.2 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RLN98042.1 - 0.00021 21.1 7.2 0.00035 20.4 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 RLN98042.1 - 0.00035 20.1 6.3 0.00061 19.4 6.3 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 RLN98042.1 - 0.017 15.2 4.8 0.036 14.1 4.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 RLN98042.1 - 0.077 13.2 5.0 0.2 11.8 5.0 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 RLN98042.1 - 0.44 10.4 9.3 0.81 9.5 9.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 RLN98042.1 - 0.88 9.7 5.6 1.8 8.8 5.6 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 RINGv PF12906.7 RLN98042.1 - 1.9 8.7 8.2 3.9 7.7 8.2 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 RLN98042.1 - 2.3 8.3 7.4 0.38 10.8 2.9 2.2 2 0 0 2 2 2 0 Zinc-finger Peptidase_C1 PF00112.23 RLN98044.1 - 7.1e-55 186.4 10.4 1.1e-54 185.8 10.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RLN98044.1 - 0.00064 18.6 0.7 0.048 12.4 0.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family CCDC53 PF10152.9 RLN98044.1 - 3.2 8.2 5.6 5.7 7.4 5.6 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF455 PF04305.14 RLN98045.1 - 7e-83 278.0 1.7 7e-83 278.0 1.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF455) DUF4180 PF13788.6 RLN98045.1 - 0.18 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4180) Peptidase_C1 PF00112.23 RLN98046.1 - 1e-53 182.7 11.8 1.4e-53 182.2 11.8 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RLN98046.1 - 0.00025 20.0 0.6 0.089 11.5 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Metallophos PF00149.28 RLN98047.1 - 0.0002 22.0 0.0 0.00021 21.9 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RLN98047.1 - 0.049 13.8 0.0 0.067 13.4 0.0 1.3 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Dimer_Tnp_hAT PF05699.14 RLN98048.1 - 4.4e-10 39.2 0.0 9.6e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Phasin PF05597.11 RLN98048.1 - 0.011 15.8 0.2 0.49 10.4 0.0 2.3 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) MFS_1 PF07690.16 RLN98049.1 - 1.1e-29 103.5 25.6 1.3e-29 103.3 25.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 RLN98049.1 - 6.2e-05 22.0 3.6 0.00055 18.9 0.3 2.3 1 1 0 2 2 2 1 MFS_1 like family Sugar_tr PF00083.24 RLN98049.1 - 0.00014 20.9 6.6 0.00014 20.9 6.6 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter ATG22 PF11700.8 RLN98049.1 - 0.00027 19.7 6.6 0.0038 15.9 0.4 2.2 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like MFS_3 PF05977.13 RLN98049.1 - 0.13 10.7 15.7 0.094 11.1 4.7 2.4 2 1 0 2 2 2 0 Transmembrane secretion effector Beta-APP PF03494.13 RLN98049.1 - 0.2 11.5 1.3 17 5.4 0.5 2.5 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) tRNA-synt_His PF13393.6 RLN98050.1 - 7.2e-44 150.3 3.4 1.5e-41 142.7 0.0 2.5 2 0 0 2 2 2 1 Histidyl-tRNA synthetase Lyase_aromatic PF00221.19 RLN98050.1 - 3.7e-23 81.9 18.2 6e-23 81.2 18.2 1.3 1 0 0 1 1 1 1 Aromatic amino acid lyase HGTP_anticodon PF03129.20 RLN98050.1 - 2.6e-17 62.7 0.0 5.9e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 RLN98050.1 - 3.4e-08 33.3 0.0 3.4e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 RLN98050.1 - 0.00049 19.3 0.0 0.00094 18.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF498 PF04430.14 RLN98050.1 - 0.079 13.0 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) DUF3870 PF12986.7 RLN98050.1 - 0.13 12.5 0.0 0.93 9.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3870) Presenilin PF01080.17 RLN98050.1 - 0.24 10.1 0.7 0.35 9.6 0.7 1.1 1 0 0 1 1 1 0 Presenilin Pinin_SDK_memA PF04696.13 RLN98050.1 - 0.88 9.6 12.7 1.5 8.9 12.7 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region THOC2_N PF16134.5 RLN98050.1 - 2.9 6.4 8.8 4.5 5.8 8.8 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Borrelia_P83 PF05262.11 RLN98050.1 - 7.3 5.0 12.7 11 4.3 12.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Glyco_hydro_12 PF01670.16 RLN98051.1 - 7.5e-44 150.3 4.1 8.7e-44 150.1 4.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 fn3 PF00041.21 RLN98053.1 - 4.9e-06 26.8 0.2 4e-05 23.9 0.2 2.2 1 1 0 1 1 1 1 Fibronectin type III domain MFS_1 PF07690.16 RLN98054.1 - 2e-11 43.4 20.4 2e-11 43.4 20.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN98054.1 - 0.018 13.9 4.9 0.062 12.1 1.3 2.3 1 1 0 2 2 2 0 Sugar (and other) transporter Thioredoxin_8 PF13905.6 RLN98056.1 - 7.5e-25 87.1 0.0 1.3e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Ribosomal_L22 PF00237.19 RLN98056.1 - 2.9e-15 56.3 0.0 1.5e-14 54.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Thioredoxin_2 PF13098.6 RLN98056.1 - 4.2e-07 30.4 0.0 9.7e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 RLN98056.1 - 6.1e-06 26.2 0.1 0.0011 18.9 0.2 2.4 1 1 1 2 2 2 1 Thioredoxin Redoxin PF08534.10 RLN98056.1 - 0.0012 18.6 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 RLN98056.1 - 0.0036 17.2 0.0 0.0058 16.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 RLN98056.1 - 0.045 13.5 0.0 0.38 10.5 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin Myelin_PLP PF01275.19 RLN98056.1 - 0.11 12.3 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) Methyltransf_3 PF01596.17 RLN98056.1 - 0.16 11.1 0.2 0.35 10.0 0.2 1.5 1 0 0 1 1 1 0 O-methyltransferase PDZ_6 PF17820.1 RLN98057.1 - 5.1e-13 48.6 0.0 9.5e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain ZZ PF00569.17 RLN98057.1 - 4.7e-10 39.1 3.3 8.4e-10 38.3 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type PDZ PF00595.24 RLN98057.1 - 1.7e-06 28.3 0.0 6.9e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 RLN98057.1 - 0.0001 22.6 0.8 0.00018 21.7 0.1 1.8 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 RLN98057.1 - 0.003 17.5 0.2 0.0085 16.0 0.0 1.8 2 0 0 2 2 2 1 Tricorn protease PDZ domain SDA1 PF05285.12 RLN98057.1 - 0.01 15.3 8.2 0.015 14.7 8.2 1.3 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 RLN98057.1 - 0.017 13.8 10.6 0.024 13.3 10.6 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GRASP55_65 PF04495.14 RLN98057.1 - 0.036 14.4 0.0 0.063 13.6 0.0 1.4 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain TFIIA PF03153.13 RLN98057.1 - 0.9 9.5 10.5 1.7 8.6 10.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CENP-N PF05238.13 RLN98057.1 - 4.6 6.4 6.1 7 5.8 6.1 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like EF-hand_1 PF00036.32 RLN98058.1 - 3.9e-27 91.7 10.9 1.4e-07 30.6 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RLN98058.1 - 5e-25 87.8 4.8 2.7e-12 47.0 0.7 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 RLN98058.1 - 2.8e-21 75.1 5.0 4.8e-11 42.3 0.1 3.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN98058.1 - 1.3e-20 71.5 9.8 1.4e-05 24.6 0.2 4.6 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RLN98058.1 - 6.5e-19 66.5 10.0 8e-06 25.1 0.1 4.6 4 0 0 4 4 4 4 EF hand Pkinase PF00069.25 RLN98058.1 - 4.1e-15 55.9 0.5 3.8e-05 23.2 0.1 3.4 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 RLN98058.1 - 5.7e-07 29.1 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.21 RLN98058.1 - 6.6e-07 29.4 11.3 1.8e-06 28.0 11.3 1.8 1 0 0 1 1 1 1 FYVE zinc finger EF-hand_4 PF12763.7 RLN98058.1 - 6.7e-06 26.0 2.5 0.011 15.7 0.1 3.5 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand FYVE_2 PF02318.16 RLN98058.1 - 0.00053 20.2 2.8 0.0014 18.9 2.8 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger SPARC_Ca_bdg PF10591.9 RLN98058.1 - 0.00054 20.3 1.6 0.023 15.0 0.0 3.0 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 RLN98058.1 - 0.0016 18.4 0.1 0.14 12.2 0.0 3.2 3 0 0 3 3 3 1 Tellurite resistance protein TerB EF-hand_9 PF14658.6 RLN98058.1 - 0.0082 16.4 0.0 0.39 11.1 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain Dockerin_1 PF00404.18 RLN98058.1 - 0.028 14.6 0.1 0.78 10.0 0.0 2.6 2 0 0 2 2 2 0 Dockerin type I domain Prok-RING_4 PF14447.6 RLN98058.1 - 0.4 10.6 6.4 1.2 9.0 6.4 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-B_box PF00643.24 RLN98058.1 - 3.7 7.8 5.3 10 6.3 5.3 1.7 1 0 0 1 1 1 0 B-box zinc finger HSP70 PF00012.20 RLN98059.1 - 2.6e-07 29.2 2.0 2.9e-07 29.1 2.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Myb_DNA-binding PF00249.31 RLN98060.1 - 1.2e-12 47.8 0.0 1.8e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN98060.1 - 0.023 14.9 0.4 0.036 14.3 0.4 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain STAG PF08514.11 RLN98060.1 - 0.14 12.1 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 STAG domain TPX2_importin PF12214.8 RLN98061.1 - 0.0059 16.8 1.0 0.097 12.9 0.1 2.4 1 1 1 2 2 2 1 Cell cycle regulated microtubule associated protein Glyco_tran_28_C PF04101.16 RLN98062.1 - 0.031 14.3 1.1 0.11 12.5 0.2 2.1 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain ATG16 PF08614.11 RLN98062.1 - 0.23 11.7 14.8 0.33 11.1 14.8 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 RLN98062.1 - 0.43 11.1 9.4 1.1 9.7 8.6 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region ADIP PF11559.8 RLN98062.1 - 0.99 9.5 10.6 0.17 11.9 4.5 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HAUS-augmin3 PF14932.6 RLN98062.1 - 2.4 7.6 12.9 1.1 8.8 7.3 2.3 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 AAA PF00004.29 RLN98063.1 - 2.3e-41 141.3 0.0 8e-31 107.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN98063.1 - 3e-10 40.7 5.6 0.0027 18.1 0.1 4.7 3 2 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 RLN98063.1 - 2.2e-08 34.5 1.9 0.05 13.9 0.1 3.9 3 2 0 4 4 3 2 AAA domain AAA_33 PF13671.6 RLN98063.1 - 8.9e-08 32.4 0.0 0.0011 19.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 RLN98063.1 - 3.1e-06 27.0 0.0 0.093 12.5 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 RLN98063.1 - 5.4e-06 26.1 1.4 0.48 10.0 0.1 3.4 2 1 1 3 3 3 2 AAA domain TIP49 PF06068.13 RLN98063.1 - 6.9e-06 25.5 0.1 0.0041 16.4 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 RLN98063.1 - 1.2e-05 25.4 0.3 0.0035 17.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 RLN98063.1 - 4.4e-05 23.5 0.0 0.45 10.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 RLN98063.1 - 7.3e-05 22.8 0.0 0.013 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 RLN98063.1 - 0.0001 21.7 0.5 0.038 13.4 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 RLN98063.1 - 0.00011 22.0 0.0 0.54 10.0 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 RLN98063.1 - 0.00017 21.4 0.2 0.064 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 RLN98063.1 - 0.00023 20.9 0.0 0.00059 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_17 PF13207.6 RLN98063.1 - 0.00028 21.3 0.0 0.033 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 RLN98063.1 - 0.00056 20.3 0.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 RLN98063.1 - 0.00085 19.3 2.4 0.3 11.0 0.1 3.4 3 1 0 3 3 3 1 NACHT domain Zeta_toxin PF06414.12 RLN98063.1 - 0.0012 18.1 0.1 0.58 9.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Rad17 PF03215.15 RLN98063.1 - 0.0014 18.6 0.0 0.2 11.5 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_19 PF13245.6 RLN98063.1 - 0.0017 18.7 2.3 3.2 8.1 0.0 3.3 2 1 1 3 3 3 1 AAA domain AAA_11 PF13086.6 RLN98063.1 - 0.0021 17.9 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.15 RLN98063.1 - 0.0023 17.9 0.1 0.33 10.9 0.0 2.9 3 0 0 3 3 3 1 NTPase AAA_18 PF13238.6 RLN98063.1 - 0.0025 18.4 0.0 0.55 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RLN98063.1 - 0.0031 17.3 0.0 0.066 12.9 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein Viral_helicase1 PF01443.18 RLN98063.1 - 0.0032 17.3 0.0 0.33 10.7 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_2 PF07724.14 RLN98063.1 - 0.0033 17.6 0.0 0.065 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Cytidylate_kin PF02224.18 RLN98063.1 - 0.0051 16.6 0.2 2.9 7.6 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase AAA_3 PF07726.11 RLN98063.1 - 0.0062 16.4 0.1 0.12 12.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 RLN98063.1 - 0.0074 16.5 0.1 0.18 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RLN98063.1 - 0.012 15.2 0.0 5.3 6.5 0.0 2.7 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 RLN98063.1 - 0.019 14.2 0.3 2.7 7.1 0.1 2.8 3 0 0 3 3 3 0 NB-ARC domain TniB PF05621.11 RLN98063.1 - 0.019 14.4 0.0 41 3.5 0.0 3.2 2 1 1 3 3 3 0 Bacterial TniB protein cobW PF02492.19 RLN98063.1 - 0.044 13.4 0.3 11 5.6 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ResIII PF04851.15 RLN98063.1 - 0.051 13.6 0.0 3 7.8 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 RLN98063.1 - 0.066 13.7 0.0 14 6.2 0.0 2.5 2 0 0 2 2 2 0 ABC transporter SKI PF01202.22 RLN98063.1 - 0.068 13.3 0.1 8.5 6.5 0.1 2.6 2 0 0 2 2 2 0 Shikimate kinase PhoH PF02562.16 RLN98063.1 - 0.086 12.3 1.3 1.9 7.9 0.2 2.7 3 0 0 3 3 3 0 PhoH-like protein Sigma54_activat PF00158.26 RLN98063.1 - 0.11 12.1 0.0 3.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AzlD PF05437.12 RLN98064.1 - 2.1 8.6 11.9 0.12 12.6 4.1 2.9 3 0 0 3 3 3 0 Branched-chain amino acid transport protein (AzlD) TetR_C_11 PF16859.5 RLN98064.1 - 2.2 8.6 5.9 2.2 8.7 0.1 3.3 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF3817 PF12823.7 RLN98064.1 - 10 7.1 7.6 1.5 9.7 2.7 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3817) Glyco_hydro_3 PF00933.21 RLN98065.1 - 4.9e-58 197.0 0.0 6.2e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN98065.1 - 7.9e-41 140.3 0.0 1.2e-40 139.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RLN98065.1 - 2.2e-12 46.9 0.0 4.8e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.11 RLN98065.1 - 0.0063 16.7 0.2 0.02 15.1 0.2 1.9 1 0 0 1 1 1 1 CARDB fn3_5 PF06280.12 RLN98065.1 - 0.1 13.3 0.1 0.2 12.3 0.1 1.4 1 0 0 1 1 1 0 Fn3-like domain DUF11 PF01345.18 RLN98065.1 - 0.56 10.6 3.4 6.9 7.0 1.9 3.5 3 1 0 3 3 3 0 Domain of unknown function DUF11 Glyco_hydro_3 PF00933.21 RLN98066.1 - 2.1e-55 188.3 0.0 2.9e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN98066.1 - 6.9e-40 137.2 0.0 1.5e-39 136.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RLN98066.1 - 6e-15 55.1 0.1 1.8e-14 53.6 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 RLN98067.1 - 1.2e-53 182.6 0.0 1.7e-53 182.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN98067.1 - 1.7e-38 132.6 0.0 2.7e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RLN98067.1 - 2.7e-14 53.0 0.0 1e-13 51.2 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain LRR_adjacent PF08191.11 RLN98067.1 - 0.047 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 LRR adjacent MFS_1 PF07690.16 RLN98068.1 - 3.5e-25 88.7 41.7 3.3e-16 59.2 23.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 RLN98068.1 - 0.059 11.8 20.9 0.0073 14.8 8.3 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Aha1_N PF09229.11 RLN98070.1 - 1.3e-15 57.8 0.0 2.6e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal zf-MYND PF01753.18 RLN98070.1 - 1.1e-09 38.2 14.3 1.8e-09 37.5 14.3 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 RLN98070.1 - 0.028 14.7 12.7 0.051 13.9 12.7 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PolC_DP2 PF03833.13 RLN98070.1 - 0.13 10.1 4.8 0.17 9.7 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Indigoidine_A PF04227.12 RLN98071.1 - 3.7e-80 269.4 1.4 2.4e-44 151.9 0.5 2.3 1 1 1 2 2 2 2 Indigoidine synthase A like protein Glyco_hydro_1 PF00232.18 RLN98072.1 - 7e-137 456.5 0.0 1.2e-93 314.0 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 1 GGA_N-GAT PF18308.1 RLN98072.1 - 0.32 10.7 3.1 14 5.4 0.2 2.4 2 0 0 2 2 2 0 GGA N-GAT domain ABC2_membrane PF01061.24 RLN98073.1 - 6.2e-44 149.9 35.0 2e-40 138.4 27.8 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN98073.1 - 2.4e-34 118.8 0.2 4e-16 59.8 0.1 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RLN98073.1 - 2.3e-07 30.9 0.1 0.059 13.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RLN98073.1 - 3.7e-07 30.7 0.1 0.02 15.3 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 RLN98073.1 - 5.7e-07 29.6 0.8 0.0052 16.7 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 RLN98073.1 - 1.5e-06 27.8 3.5 0.014 15.1 0.6 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 RLN98073.1 - 7.3e-06 25.7 0.1 0.044 13.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RLN98073.1 - 4.2e-05 22.9 0.7 0.0055 16.0 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 RLN98073.1 - 0.00016 22.0 0.1 0.38 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 RLN98073.1 - 0.00075 19.3 0.5 0.61 9.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RLN98073.1 - 0.0012 19.4 0.2 0.33 11.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RLN98073.1 - 0.0021 18.5 0.4 3.7 8.0 0.2 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 RLN98073.1 - 0.0044 16.5 1.5 1 8.7 0.2 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 RLN98073.1 - 0.0078 16.2 0.1 0.33 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 RLN98073.1 - 0.0094 16.5 0.1 8 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 RLN98073.1 - 0.014 15.4 0.3 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 G-alpha PF00503.20 RLN98073.1 - 0.016 14.4 0.1 0.081 12.1 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit cobW PF02492.19 RLN98073.1 - 0.025 14.2 2.1 0.81 9.2 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 RLN98073.1 - 0.029 14.3 4.6 2.6 7.9 0.2 2.7 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 RLN98073.1 - 0.031 14.3 0.8 0.76 9.8 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 RLN98073.1 - 0.038 13.7 1.5 1.7 8.3 0.2 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 RLN98073.1 - 0.04 14.0 2.9 4.4 7.4 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 RLN98073.1 - 0.045 13.7 0.0 3.1 7.6 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 RLN98073.1 - 0.048 13.8 0.1 6.9 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 RLN98073.1 - 0.049 13.0 1.0 1.2 8.5 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI ABC_ATPase PF09818.9 RLN98073.1 - 0.054 12.3 0.4 3.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class RNA_helicase PF00910.22 RLN98073.1 - 0.065 13.6 0.5 10 6.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 RLN98073.1 - 0.082 13.1 0.5 17 5.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 RLN98073.1 - 0.085 13.2 0.5 8.1 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RLN98073.1 - 0.093 12.4 1.1 13 5.5 0.6 2.4 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 RLN98073.1 - 0.32 10.0 1.1 2.3 7.2 0.0 2.5 3 0 0 3 3 3 0 MCM P-loop domain AAA_7 PF12775.7 RLN98073.1 - 0.33 10.4 1.3 2.9 7.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region PDR_CDR PF06422.12 RLN98073.1 - 1.4 8.9 5.6 1.7 8.6 1.6 2.8 3 0 0 3 3 2 0 CDR ABC transporter DUF87 PF01935.17 RLN98073.1 - 2.6 8.1 7.3 8.6 6.4 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain DUF3810 PF12725.7 RLN98073.1 - 4.7 6.5 7.5 23 4.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) RNA_pol_Rpc82 PF05645.13 RLN98074.1 - 1.8e-07 31.2 0.1 1.9e-05 24.6 0.0 3.1 2 1 1 3 3 3 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 RLN98074.1 - 1.5e-05 25.0 0.1 0.045 13.8 0.0 2.6 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 RLN98074.1 - 0.00055 19.8 0.1 0.0016 18.3 0.1 1.8 1 0 0 1 1 1 1 TFIIE alpha subunit Ephrin_rec_like PF07699.13 RLN98076.1 - 8.2e-17 60.7 30.0 6.7e-07 29.0 5.8 6.8 4 2 3 7 7 7 5 Putative ephrin-receptor like TNFR_c6 PF00020.18 RLN98076.1 - 0.0022 18.3 32.6 0.0096 16.3 1.0 7.3 4 3 4 8 8 8 5 TNFR/NGFR cysteine-rich region DUF2484 PF10658.9 RLN98076.1 - 2.7 8.3 4.1 2.1 8.7 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2484) Wtap PF17098.5 RLN98077.1 - 0.0021 18.0 9.4 0.16 11.9 1.3 2.3 2 0 0 2 2 2 2 WTAP/Mum2p family BRE1 PF08647.11 RLN98077.1 - 1.3 9.2 18.1 1.9 8.6 11.1 2.2 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase SID-1_RNA_chan PF13965.6 RLN98077.1 - 5.9 5.2 4.5 6.3 5.1 4.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RINGv PF12906.7 RLN98078.1 - 4.3e-11 42.8 4.3 9.1e-11 41.7 4.3 1.6 1 0 0 1 1 1 1 RING-variant domain FHA PF00498.26 RLN98078.1 - 2.6e-08 34.1 0.0 8.3e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 RLN98078.1 - 0.00092 19.5 0.0 0.0023 18.2 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_2 PF13639.6 RLN98078.1 - 2.6 8.4 5.3 16 5.9 5.8 2.1 1 1 1 2 2 2 0 Ring finger domain WD40 PF00400.32 RLN98079.1 - 3.6e-28 97.2 23.4 0.00012 22.8 0.4 9.9 11 0 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN98079.1 - 2.2e-12 47.1 0.0 0.0027 18.0 0.0 6.2 5 3 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN98079.1 - 0.0017 17.4 0.1 3 6.7 0.0 3.5 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 RLN98079.1 - 0.0054 16.3 4.7 0.32 10.5 0.2 3.3 3 0 0 3 3 3 1 PQQ-like domain Nup160 PF11715.8 RLN98079.1 - 0.0087 14.8 0.9 0.15 10.6 0.2 2.8 2 1 1 3 3 3 1 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 RLN98079.1 - 0.011 15.1 0.0 0.088 12.1 0.0 2.4 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Hira PF07569.11 RLN98079.1 - 0.056 13.2 1.5 7.5 6.2 0.0 3.8 4 1 1 5 5 5 0 TUP1-like enhancer of split Cytochrom_D1 PF02239.16 RLN98079.1 - 0.086 11.4 0.0 0.42 9.1 0.0 2.2 3 0 0 3 3 3 0 Cytochrome D1 heme domain GTP_EFTU PF00009.27 RLN98080.1 - 7.8e-64 214.8 0.0 1.3e-63 214.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 RLN98080.1 - 2.5e-27 94.8 0.0 5.9e-27 93.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 RLN98080.1 - 7.4e-21 74.0 0.0 1.8e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 RLN98080.1 - 1.4e-10 41.0 0.0 3.5e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 RLN98080.1 - 3.2e-08 33.8 0.1 8.7e-08 32.5 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 RLN98080.1 - 2e-07 30.9 0.0 4.3e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 RLN98080.1 - 0.019 15.0 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase HEAT_EZ PF13513.6 RLN98080.1 - 0.077 13.5 0.8 23 5.6 0.3 2.8 2 0 0 2 2 2 0 HEAT-like repeat DRAT PF07357.11 RLN98080.1 - 0.14 11.4 0.0 0.33 10.1 0.0 1.6 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) TPX2 PF06886.11 RLN98081.1 - 9.4e-11 41.8 19.8 9.4e-11 41.8 19.8 6.7 7 0 0 7 7 7 2 Targeting protein for Xklp2 (TPX2) TPX2_importin PF12214.8 RLN98081.1 - 7.4e-05 23.0 71.7 0.0001 22.5 17.3 7.1 5 1 2 7 7 7 2 Cell cycle regulated microtubule associated protein Pyrophosphatase PF00719.19 RLN98082.1 - 4.9e-47 159.7 0.0 5.8e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase E1-E2_ATPase PF00122.20 RLN98083.1 - 3.7e-12 46.1 0.0 5.6e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 E1-E2 ATPase DUF4058 PF13267.6 RLN98083.1 - 0.014 14.8 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) Cation_ATPase_N PF00690.26 RLN98083.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus BORG_CEP PF14957.6 RLN98083.1 - 0.096 13.9 0.0 0.18 13.0 0.0 1.4 1 0 0 1 1 1 0 Cdc42 effector Kinesin PF00225.23 RLN98084.1 - 4.7e-36 124.4 0.0 6.3e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN98084.1 - 2.8e-18 66.3 0.0 6.3e-18 65.1 0.0 1.6 2 0 0 2 2 2 1 Microtubule binding Aldedh PF00171.22 RLN98086.1 - 1.2e-72 244.9 0.0 1.5e-72 244.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1515 PF07439.11 RLN98086.1 - 0.097 12.7 0.5 3.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) eIF3_subunit PF08597.10 RLN98087.1 - 9.8e-37 127.2 13.5 1.4e-36 126.7 13.5 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Alpha-2-MRAP_N PF06400.11 RLN98087.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.4 3 0 0 3 3 3 0 Alpha-2-macroglobulin RAP, N-terminal domain PS_Dcarbxylase PF02666.15 RLN98089.1 - 1.3e-59 201.1 0.0 1.8e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase EHD_N PF16880.5 RLN98089.1 - 0.12 12.3 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 N-terminal EH-domain containing protein bZIP_1 PF00170.21 RLN98090.1 - 3.2e-09 36.7 17.4 3.2e-09 36.7 17.4 4.4 4 1 1 5 5 5 1 bZIP transcription factor bZIP_2 PF07716.15 RLN98090.1 - 1.1e-06 28.6 12.5 1.1e-06 28.6 12.5 3.7 4 1 0 4 4 4 1 Basic region leucine zipper Sigma70_r3 PF04539.16 RLN98090.1 - 0.012 15.7 0.7 0.2 11.8 0.0 2.9 3 0 0 3 3 3 0 Sigma-70 region 3 HTH_20 PF12840.7 RLN98090.1 - 0.049 13.7 0.1 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain YabA PF06156.13 RLN98090.1 - 0.18 12.5 16.6 0.62 10.7 0.8 3.3 2 1 1 3 3 3 0 Initiation control protein YabA Med15_fungi PF05397.12 RLN98090.1 - 0.91 9.8 5.2 0.22 11.8 0.6 2.1 2 0 0 2 2 2 0 Mediator complex subunit 15 DUF2345 PF10106.9 RLN98092.1 - 0.057 13.3 7.6 0.2 11.5 5.8 2.3 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) Cation_ATPase_C PF00689.21 RLN98093.1 - 5e-51 173.0 7.5 6.9e-51 172.5 1.0 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 RLN98093.1 - 3.4e-30 104.9 1.2 3.1e-21 75.7 0.1 3.7 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase PF13246.6 RLN98093.1 - 2.7e-18 65.8 0.0 5.4e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RLN98093.1 - 1.5e-14 54.8 0.9 8.8e-14 52.3 0.9 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RLN98093.1 - 4.1e-12 45.6 0.0 1.1e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus ATP_Ca_trans_C PF12424.8 RLN98093.1 - 1.9e-07 31.5 1.0 4.4e-07 30.3 1.0 1.6 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Hydrolase_3 PF08282.12 RLN98093.1 - 1.1e-05 25.3 1.9 0.0006 19.6 1.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF962 PF06127.11 RLN98093.1 - 0.043 13.9 0.9 0.46 10.6 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Na_Pi_cotrans PF02690.15 RLN98094.1 - 6.4e-21 74.9 6.4 8.3e-21 74.5 6.4 1.1 1 0 0 1 1 1 1 Na+/Pi-cotransporter RhodobacterPufX PF11511.8 RLN98094.1 - 0.052 13.1 1.2 0.15 11.7 1.2 1.7 1 0 0 1 1 1 0 Intrinsic membrane protein PufX PEMT PF04191.13 RLN98094.1 - 0.14 12.6 3.1 0.11 13.0 1.0 1.8 1 1 1 2 2 2 0 Phospholipid methyltransferase Bac_export_1 PF01311.20 RLN98094.1 - 0.4 10.2 9.3 1.3 8.6 0.7 2.1 1 1 1 2 2 2 0 Bacterial export proteins, family 1 Ank_2 PF12796.7 RLN98095.1 - 6.2e-26 90.8 2.5 6.2e-08 33.1 0.2 4.8 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 RLN98095.1 - 2.3e-21 75.2 5.6 3.8e-05 23.9 0.1 7.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 RLN98095.1 - 8.2e-21 74.1 0.3 0.00085 19.8 0.0 6.2 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN98095.1 - 2.7e-19 69.0 6.7 0.0065 16.8 0.0 7.7 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN98095.1 - 9.7e-15 53.2 2.9 2.9 8.7 0.0 9.1 9 0 0 9 9 9 4 Ankyrin repeat Toxin_15 PF07906.13 RLN98095.1 - 0.059 13.0 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 ShET2 enterotoxin, N-terminal region VPS9 PF02204.18 RLN98096.1 - 1.9e-12 47.3 0.0 3.7e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF4672 PF15716.5 RLN98096.1 - 0.069 12.8 0.0 0.43 10.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4672) PX PF00787.24 RLN98096.1 - 0.16 12.0 0.1 0.71 9.9 0.0 2.1 2 0 0 2 2 2 0 PX domain ASH PF15780.5 RLN98097.1 - 3.6e-29 100.9 10.1 0.023 14.9 0.1 12.3 11 1 0 11 11 11 7 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 RLN98097.1 - 2.1e-09 37.2 0.2 6.4 6.7 0.0 7.7 10 0 0 10 10 10 3 MSP (Major sperm protein) domain MYCBPAP PF14646.6 RLN98097.1 - 0.001 18.1 0.0 0.41 9.5 0.0 4.0 4 0 0 4 4 4 1 MYCBP-associated protein family TMEM131_like PF12371.8 RLN98097.1 - 0.0036 17.5 3.2 3.3 8.0 0.0 5.3 5 0 0 5 5 5 1 Transmembrane protein 131-like PapD-like PF14874.6 RLN98097.1 - 0.062 13.5 2.9 25 5.1 0.0 5.4 7 0 0 7 7 7 0 Flagellar-associated PapD-like Chlor_dismutase PF06778.12 RLN98097.1 - 0.16 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Chlorite dismutase DS PF01916.17 RLN98098.1 - 2.2e-129 430.8 0.0 2.6e-129 430.6 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Clathrin PF00637.20 RLN98099.1 - 0.034 14.0 0.4 0.43 10.4 0.0 2.7 3 0 0 3 3 3 0 Region in Clathrin and VPS FtsJ PF01728.19 RLN98100.1 - 4.9e-57 192.9 0.3 1.4e-56 191.4 0.2 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Spb1_C PF07780.12 RLN98100.1 - 4e-56 190.0 20.8 4e-56 190.0 20.8 4.0 4 0 0 4 4 4 1 Spb1 C-terminal domain DUF3381 PF11861.8 RLN98100.1 - 7.2e-23 81.2 7.9 7.2e-23 81.2 7.9 5.1 5 1 1 6 6 6 1 Domain of unknown function (DUF3381) OHCU_decarbox PF09349.10 RLN98100.1 - 2.7 8.5 10.7 0.042 14.3 1.5 2.5 2 0 0 2 2 2 0 OHCU decarboxylase Metallophos PF00149.28 RLN98101.1 - 8e-08 33.0 0.0 1.5e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PB1 PF00564.24 RLN98103.1 - 7.1e-07 29.1 0.0 1.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 PB1 domain CUE PF02845.16 RLN98103.1 - 0.15 11.8 1.9 1.2 8.9 0.2 2.6 3 0 0 3 3 3 0 CUE domain Kinesin PF00225.23 RLN98104.1 - 6.2e-103 344.2 2.2 1.1e-102 343.5 0.0 2.3 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RLN98104.1 - 7e-45 152.6 0.1 2e-44 151.1 0.1 1.9 1 0 0 1 1 1 1 Microtubule binding WW PF00397.26 RLN98104.1 - 3.7e-06 26.9 2.4 7.8e-06 25.9 2.4 1.6 1 0 0 1 1 1 1 WW domain Filament PF00038.21 RLN98104.1 - 1.8e-05 24.5 22.6 1.8e-05 24.5 22.6 3.3 1 1 2 3 3 3 1 Intermediate filament protein DUF1730 PF08331.10 RLN98104.1 - 0.069 13.1 0.2 0.37 10.7 0.2 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) Castor_Poll_mid PF06241.12 RLN98105.1 - 5.8e-27 93.7 0.0 3.1e-26 91.4 0.0 2.2 2 0 0 2 2 2 1 Castor and Pollux, part of voltage-gated ion channel TrkA_C PF02080.21 RLN98105.1 - 1.3e-05 24.9 0.0 0.00015 21.5 0.0 2.8 3 0 0 3 3 3 1 TrkA-C domain Ank_4 PF13637.6 RLN98106.1 - 1.7e-33 114.6 23.3 5.8e-05 23.6 0.1 9.6 6 2 4 10 10 10 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN98106.1 - 1.6e-32 111.9 14.5 2.3e-06 28.1 0.0 7.1 3 2 3 7 7 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN98106.1 - 5.2e-27 93.6 31.1 0.0011 19.2 0.0 14.5 5 1 10 15 15 14 10 Ankyrin repeats (many copies) Castor_Poll_mid PF06241.12 RLN98106.1 - 2.5e-26 91.7 0.0 1.2e-25 89.5 0.0 2.1 2 0 0 2 2 2 1 Castor and Pollux, part of voltage-gated ion channel Ank_3 PF13606.6 RLN98106.1 - 9.5e-09 34.8 13.0 47 5.0 0.0 11.9 11 2 2 13 13 12 0 Ankyrin repeat DUF5049 PF16468.5 RLN98106.1 - 2.1e-05 24.3 0.1 3.8 7.5 0.0 7.8 7 3 4 11 11 11 1 Domain of unknown function (DUF5049) TrkA_C PF02080.21 RLN98106.1 - 0.00013 21.7 0.0 0.00073 19.3 0.0 2.3 2 0 0 2 2 2 1 TrkA-C domain Ank PF00023.30 RLN98106.1 - 0.0024 18.2 3.1 95 3.7 0.0 8.4 7 4 2 9 9 8 0 Ankyrin repeat EccE PF11203.8 RLN98106.1 - 0.047 14.0 0.4 0.31 11.4 0.4 2.5 1 0 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE Baculo_LEF5_C PF11792.8 RLN98106.1 - 0.64 9.7 2.6 1.5e+02 2.1 0.0 4.4 3 1 1 4 4 4 0 Baculoviridae late expression factor 5 C-terminal domain TGBp3 PF02495.17 RLN98106.1 - 3.2 7.5 4.3 98 2.7 0.0 5.0 7 0 0 7 7 7 0 Triple gene block 3 DUF3322 PF11795.8 RLN98106.1 - 3.9 7.4 8.3 20 5.1 0.0 4.8 4 1 2 6 6 5 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Myb_DNA-binding PF00249.31 RLN98107.1 - 4e-13 49.3 0.0 6.9e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN98107.1 - 0.0022 18.2 0.0 0.0045 17.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain TLD PF07534.16 RLN98108.1 - 1.7e-30 106.1 0.0 2.6e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 TLD PDZ PF00595.24 RLN98108.1 - 0.014 15.7 0.2 0.058 13.7 0.0 2.1 2 0 0 2 2 2 0 PDZ domain PDZ_6 PF17820.1 RLN98108.1 - 0.021 14.6 0.0 2.1 8.3 0.2 2.8 2 0 0 2 2 2 0 PDZ domain DUF2293 PF10056.9 RLN98109.1 - 0.0095 16.2 0.4 0.03 14.5 0.3 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) Sugar_tr PF00083.24 RLN98111.1 - 3.7e-26 92.0 28.3 9.2e-24 84.1 10.8 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RLN98111.1 - 5.2e-20 71.7 51.9 1.5e-18 66.8 15.6 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF2574 PF10836.8 RLN98112.1 - 0.44 10.4 3.6 0.93 9.4 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2574) Abhydrolase_1 PF00561.20 RLN98113.1 - 2.5e-10 40.4 0.0 5.8e-09 36.0 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN98113.1 - 2.8e-07 30.1 0.0 6.1e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF915 PF06028.11 RLN98113.1 - 0.00031 20.1 0.0 0.00064 19.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.7 RLN98113.1 - 0.0067 17.1 0.0 0.015 15.9 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RLN98114.1 - 2.4e-12 47.1 0.0 5e-12 46.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN98114.1 - 1.6e-08 34.1 0.0 2.7e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN98114.1 - 4.7e-07 30.6 0.0 1.2e-05 26.0 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 RLN98114.1 - 7.9e-05 22.1 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Aldedh PF00171.22 RLN98116.1 - 5.7e-99 331.7 0.1 4.4e-50 170.5 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family PI3Ka PF00613.20 RLN98117.1 - 1.1e-42 145.6 0.1 2.1e-42 144.6 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PH PF00169.29 RLN98117.1 - 1.8e-29 102.3 1.0 9.6e-14 51.8 0.4 2.8 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 RLN98117.1 - 1e-12 48.4 1.9 2.6e-05 24.6 0.0 2.9 2 0 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 RLN98117.1 - 2.6e-09 37.2 3.5 0.0032 17.7 1.3 3.7 2 1 0 2 2 2 2 Pleckstrin homology domain PI3K_rbd PF00794.18 RLN98117.1 - 1e-07 32.1 0.1 2.7e-07 30.7 0.1 1.8 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 RLN98117.1 - 2.9e-05 24.0 0.0 5.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 CRM1_C PF08767.11 RLN98117.1 - 0.043 13.0 0.1 0.21 10.7 0.0 2.0 2 0 0 2 2 2 0 CRM1 C terminal DUF2833 PF11090.8 RLN98117.1 - 0.044 14.2 2.6 0.052 13.9 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2833) HU-CCDC81_euk_1 PF14908.6 RLN98118.1 - 4.4e-13 49.2 0.0 1.4e-12 47.6 0.0 1.9 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_euk_2 PF18289.1 RLN98118.1 - 5.4e-13 48.9 0.2 1.5e-12 47.5 0.1 1.9 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 2 RNase_H PF00075.24 RLN98118.1 - 0.1 12.8 0.2 0.23 11.7 0.2 1.6 1 0 0 1 1 1 0 RNase H zf-U11-48K PF05253.12 RLN98118.1 - 0.26 11.2 0.9 5.7 7.0 0.1 2.7 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger SAPS PF04499.15 RLN98120.1 - 3.5e-20 72.3 15.0 9.1e-15 54.4 0.0 4.6 3 1 1 4 4 4 4 SIT4 phosphatase-associated protein DUF966 PF06136.13 RLN98120.1 - 5.4 6.6 9.3 9.8 5.8 7.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Jacalin PF01419.17 RLN98122.1 - 2.2e-08 34.1 0.1 5.3e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 Jacalin-like lectin domain BRX PF08381.11 RLN98122.1 - 0.0025 17.1 0.4 0.011 15.1 0.4 2.1 1 0 0 1 1 1 1 Transcription factor regulating root and shoot growth via Pin3 DUF659 PF04937.15 RLN98123.1 - 9.9e-31 106.7 0.0 2e-30 105.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Proteasome PF00227.26 RLN98124.1 - 7.6e-15 54.9 0.1 1e-14 54.5 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RLN98124.1 - 3.9e-13 48.8 0.0 5.2e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature BT1 PF03092.16 RLN98125.1 - 7.9e-16 57.4 12.9 1.6e-12 46.4 1.4 3.2 3 0 0 3 3 3 3 BT1 family PUCC PF03209.15 RLN98125.1 - 0.0018 17.4 3.5 0.0018 17.4 3.5 2.4 2 1 0 2 2 2 1 PUCC protein DUF2975 PF11188.8 RLN98125.1 - 0.65 9.9 5.5 9 6.2 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) Proteasome PF00227.26 RLN98126.1 - 1.9e-29 102.6 0.0 2.1e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit zf-CCHC_2 PF13696.6 RLN98126.1 - 0.05 13.4 0.1 0.082 12.7 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle OTU PF02338.19 RLN98127.1 - 2e-16 60.6 0.0 7e-16 58.9 0.0 2.0 1 0 0 1 1 1 1 OTU-like cysteine protease Ank_4 PF13637.6 RLN98127.1 - 2.6e-13 50.2 0.8 7.3e-08 32.8 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN98127.1 - 4.3e-10 39.6 2.6 2.2e-06 27.8 0.1 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN98127.1 - 1.6e-08 35.0 0.2 3.3e-08 34.0 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 RLN98127.1 - 1.3e-07 31.8 0.8 0.0026 18.1 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 RLN98127.1 - 1.3e-06 28.2 0.1 0.012 16.1 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Peptidase_C65 PF10275.9 RLN98127.1 - 0.039 13.4 1.1 3.1 7.2 0.0 2.5 3 0 0 3 3 3 0 Peptidase C65 Otubain UIM PF02809.20 RLN98127.1 - 5.8 7.1 31.4 1.3 9.1 2.9 5.4 6 0 0 6 6 6 0 Ubiquitin interaction motif Gaa1 PF04114.14 RLN98129.1 - 7.3e-72 243.0 5.3 2.7e-70 237.8 0.0 2.5 2 1 0 2 2 2 2 Gaa1-like, GPI transamidase component Sec3-PIP2_bind PF15277.6 RLN98130.1 - 0.0038 17.3 0.0 0.0067 16.5 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C PF09763.9 RLN98131.1 - 1.1e-13 50.5 15.6 1.2e-05 24.0 0.5 3.9 3 1 1 4 4 4 3 Exocyst complex component Sec3 DUF4509 PF14970.6 RLN98131.1 - 0.0033 17.4 0.1 0.0087 16.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4509) GTF2I PF02946.14 RLN98131.1 - 0.16 12.0 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 GTF2I-like repeat CENP-F_leu_zip PF10473.9 RLN98132.1 - 0.043 13.8 1.0 0.069 13.2 1.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FPP PF05911.11 RLN98132.1 - 0.062 11.5 0.4 0.083 11.1 0.4 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil SlyX PF04102.12 RLN98132.1 - 0.51 11.0 6.9 2 9.1 0.5 2.5 1 1 1 2 2 2 0 SlyX Guanylate_cyc PF00211.20 RLN98134.1 - 1.1e-09 38.1 0.0 9.3e-09 35.2 0.0 2.1 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Endosulfine PF04667.17 RLN98135.1 - 9.8e-26 89.7 3.0 8.8e-10 38.6 0.0 5.0 4 1 1 5 5 5 4 cAMP-regulated phosphoprotein/endosulfine conserved region zf-RING_6 PF14835.6 RLN98136.1 - 3 7.8 12.3 7.9 6.4 12.3 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Methyltrn_RNA_3 PF02598.17 RLN98137.1 - 1.8e-104 349.3 0.0 2.4e-104 348.8 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methyltransferase FAM60A PF15396.6 RLN98137.1 - 0.092 12.7 3.9 0.035 14.1 1.4 1.6 2 0 0 2 2 2 0 Protein Family FAM60A MCM_bind PF09739.9 RLN98137.1 - 0.12 10.8 5.5 0.16 10.4 5.5 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor CDK5_activator PF03261.15 RLN98137.1 - 1 8.9 3.3 1.4 8.4 3.3 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Presenilin PF01080.17 RLN98137.1 - 1.6 7.4 6.5 2 7.1 6.5 1.1 1 0 0 1 1 1 0 Presenilin rRNA_processing PF08524.11 RLN98137.1 - 2.7 8.0 18.1 4.4 7.3 18.1 1.2 1 0 0 1 1 1 0 rRNA processing CDC45 PF02724.14 RLN98137.1 - 3.2 5.9 11.4 4.6 5.4 11.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.10 RLN98137.1 - 3.7 7.9 14.2 6.2 7.1 14.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 LCD1 PF09798.9 RLN98137.1 - 5.8 5.3 7.5 7.2 5.0 7.5 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein TPR_12 PF13424.6 RLN98138.1 - 9.1e-05 22.7 21.2 0.002 18.4 4.4 3.4 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 RLN98138.1 - 0.02 14.7 5.7 2 8.4 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 RLN98138.1 - 0.35 9.9 0.9 0.5 9.4 0.9 1.1 1 0 0 1 1 1 0 Coatomer WD associated region LRR_8 PF13855.6 RLN98139.1 - 7.6e-23 80.0 11.0 1.5e-08 34.3 0.9 4.3 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 RLN98139.1 - 1.1e-14 54.3 17.9 9.6e-07 29.0 2.1 5.5 2 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN98139.1 - 4.4e-09 35.6 6.3 1.5 9.7 0.1 6.6 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 RLN98139.1 - 1.6e-06 27.7 6.4 3.2 8.0 0.0 6.0 5 0 0 5 5 5 3 Leucine Rich repeat LRR_9 PF14580.6 RLN98139.1 - 4.8e-05 22.9 4.5 0.024 14.1 0.8 2.5 1 1 1 2 2 2 2 Leucine-rich repeat Nyv1_N PF09426.10 RLN98139.1 - 0.022 14.8 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 Vacuolar R-SNARE Nyv1 N terminal MIG-14_Wnt-bd PF06664.12 RLN98140.1 - 1.4e-62 211.5 18.9 1.4e-62 211.5 18.9 1.5 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion DHHC PF01529.20 RLN98140.1 - 0.44 10.7 12.8 0.072 13.2 2.7 2.9 2 0 0 2 2 2 0 DHHC palmitoyltransferase OAD_gamma PF04277.13 RLN98140.1 - 4.9 7.8 12.4 11 6.6 0.1 3.8 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain EGF_2 PF07974.13 RLN98141.1 - 0.00018 21.8 3.6 0.00018 21.8 3.6 4.0 4 0 0 4 4 4 3 EGF-like domain zf-TFIIB PF13453.6 RLN98141.1 - 0.045 13.1 0.1 0.11 11.8 0.1 1.7 1 0 0 1 1 1 0 Transcription factor zinc-finger D_CNTX PF17492.2 RLN98141.1 - 4.4 7.6 11.3 10 6.4 2.2 3.5 3 0 0 3 3 3 0 Delta Ctenitoxins DAHP_synth_2 PF01474.16 RLN98142.1 - 2.2e-186 619.6 0.0 5e-186 618.5 0.0 1.5 1 1 0 1 1 1 1 Class-II DAHP synthetase family CBS PF00571.28 RLN98143.1 - 3.4e-112 366.8 61.3 4e-07 30.4 0.1 21.8 22 0 0 22 22 22 18 CBS domain PB1 PF00564.24 RLN98143.1 - 1.1e-08 34.9 0.2 4.4e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 PB1 domain Myosin_head PF00063.21 RLN98143.1 - 0.00043 18.6 0.0 0.0006 18.2 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 RLN98143.1 - 0.00056 19.5 7.8 0.052 13.4 0.0 3.7 3 0 0 3 3 3 2 IQ calmodulin-binding motif DUF4808 PF16066.5 RLN98143.1 - 0.029 14.9 5.1 1 9.9 0.3 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4808) LUC7 PF03194.15 RLN98143.1 - 0.27 10.9 15.0 2.7 7.6 7.4 2.8 1 1 0 2 2 2 0 LUC7 N_terminus HlyD_2 PF12700.7 RLN98143.1 - 0.9 8.2 14.3 2.1 7.0 5.9 2.3 1 1 1 2 2 2 0 HlyD family secretion protein DUF1192 PF06698.11 RLN98143.1 - 1.4 9.0 16.3 0.24 11.5 2.8 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Pox_F11 PF04943.12 RLN98143.1 - 5.7 5.9 7.4 16 4.5 7.4 1.7 1 0 0 1 1 1 0 Poxvirus F11 protein DUF2063 PF09836.9 RLN98144.1 - 0.1 12.8 0.1 0.56 10.5 0.0 2.0 2 0 0 2 2 2 0 Putative DNA-binding domain EF-hand_1 PF00036.32 RLN98145.1 - 7.6e-42 137.8 14.2 2.9e-10 38.9 1.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RLN98145.1 - 1e-35 122.0 3.4 5.3e-18 65.2 1.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RLN98145.1 - 1.6e-32 111.1 12.1 2.1e-16 59.5 0.9 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 RLN98145.1 - 2.2e-30 101.9 7.7 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RLN98145.1 - 8.7e-27 91.4 10.5 2.3e-06 26.8 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 RLN98145.1 - 2.2e-16 59.9 0.2 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 RLN98145.1 - 7.2e-10 38.8 0.8 0.00014 21.8 0.2 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RLN98145.1 - 2e-08 34.5 0.0 0.0022 18.3 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 RLN98145.1 - 4.2e-07 30.8 0.0 0.00016 22.5 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 RLN98145.1 - 8.7e-06 25.7 0.9 0.042 13.9 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 RLN98145.1 - 6.4e-05 23.0 1.0 0.00037 20.5 0.1 2.4 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 RLN98145.1 - 0.00027 21.0 3.9 0.045 13.9 0.3 2.8 1 1 0 2 2 2 2 Dockerin type I domain RNA_pol_Rpb4 PF03874.16 RLN98145.1 - 0.0013 19.0 0.4 0.73 10.2 0.1 2.5 3 0 0 3 3 2 1 RNA polymerase Rpb4 TerB PF05099.13 RLN98145.1 - 0.0017 18.3 0.3 0.58 10.1 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB DUF1103 PF06513.11 RLN98145.1 - 0.0019 17.9 2.1 0.0022 17.7 2.1 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF3349 PF11829.8 RLN98145.1 - 0.0019 18.9 0.4 1.2 10.0 0.0 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 RLN98145.1 - 0.0024 17.8 1.4 0.49 10.3 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein DUF5580 PF17743.1 RLN98145.1 - 0.0074 14.9 0.0 0.0074 14.9 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) DUF853 PF05872.12 RLN98145.1 - 0.022 13.4 0.1 0.6 8.6 0.0 2.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Poly_export PF02563.16 RLN98145.1 - 0.028 14.6 0.1 4.1 7.7 0.0 3.1 1 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein SurA_N_2 PF13623.6 RLN98145.1 - 0.029 14.2 0.6 1.7 8.5 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain MotA_activ PF09114.10 RLN98145.1 - 0.035 14.2 0.4 0.54 10.4 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 RLN98145.1 - 0.047 12.9 0.1 3.8 6.6 0.1 2.2 1 1 0 2 2 2 0 Cache domain Fe_hyd_lg_C PF02906.14 RLN98145.1 - 0.061 13.0 1.0 0.24 11.0 1.0 1.9 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain EF-hand_14 PF17959.1 RLN98145.1 - 0.075 13.4 0.2 9.2 6.7 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain SapB_1 PF05184.15 RLN98145.1 - 0.27 11.3 2.7 27 4.9 0.0 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 1 zf-RNPHF PF08080.12 RLN98147.1 - 0.032 14.2 0.6 38 4.3 0.0 3.9 4 0 0 4 4 4 0 RNPHF zinc finger 5_nucleotid_C PF02872.18 RLN98148.1 - 6.8e-21 75.1 0.0 1.2e-20 74.3 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 RLN98148.1 - 3.9e-07 30.8 0.0 6.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ferlin_C PF16165.5 RLN98149.1 - 6.6 6.7 7.2 0.31 11.0 1.1 1.8 2 0 0 2 2 2 0 Ferlin C-terminus STIMATE PF12400.8 RLN98150.1 - 4.6e-36 124.1 3.6 7.6e-36 123.4 3.6 1.4 1 0 0 1 1 1 1 STIMATE family NicO PF03824.16 RLN98150.1 - 0.85 8.9 9.2 0.44 9.8 5.4 2.0 2 0 0 2 2 2 0 High-affinity nickel-transport protein Myotub-related PF06602.14 RLN98151.1 - 2.7e-118 395.0 0.0 4.2e-118 394.3 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 RLN98151.1 - 4.1e-06 26.7 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Y_phosphatase3 PF13350.6 RLN98151.1 - 0.062 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family UPF0242 PF06785.11 RLN98151.1 - 0.066 13.3 2.2 0.12 12.5 2.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 RLN98151.1 - 0.11 12.5 1.1 0.28 11.2 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 RLN98151.1 - 0.68 10.4 4.6 1.4 9.4 4.6 1.4 1 0 0 1 1 1 0 Snapin/Pallidin DivIC PF04977.15 RLN98151.1 - 4.9 7.0 5.0 11 5.9 5.0 1.5 1 0 0 1 1 1 0 Septum formation initiator C2 PF00168.30 RLN98152.1 - 9.9e-11 41.9 0.0 1.7e-06 28.3 0.0 3.3 2 1 0 2 2 2 2 C2 domain EGF_2 PF07974.13 RLN98153.1 - 7.6e-06 26.2 57.8 0.0026 18.1 9.4 5.8 6 0 0 6 6 6 4 EGF-like domain EGF PF00008.27 RLN98153.1 - 0.015 15.6 6.2 0.015 15.6 6.2 6.1 6 1 0 6 6 6 0 EGF-like domain Laminin_EGF PF00053.24 RLN98153.1 - 0.048 13.8 45.3 0.44 10.7 0.6 4.6 4 1 1 5 5 5 0 Laminin EGF domain Cellulase PF00150.18 RLN98154.1 - 1.2e-26 93.8 4.8 1.5e-26 93.5 4.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 RLN98155.1 - 0.0062 16.0 0.0 0.0075 15.7 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NPA PF16469.5 RLN98157.1 - 0.14 12.8 0.3 0.38 11.3 0.3 1.7 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 CbiG_C PF01890.16 RLN98157.1 - 0.19 12.3 5.6 8.4 7.0 1.1 2.9 2 0 0 2 2 2 0 Cobalamin synthesis G C-terminus PE PF00934.20 RLN98157.1 - 6 7.3 10.2 0.98 9.8 4.5 2.8 2 1 0 2 2 2 0 PE family Sec34 PF04136.15 RLN98158.1 - 1.1e-08 35.1 0.0 1.6e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 Sec34-like family BLOC1_2 PF10046.9 RLN98158.1 - 0.03 14.6 0.3 1.3 9.4 0.0 2.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DnaJ PF00226.31 RLN98161.1 - 1.1e-10 41.4 0.0 3.7e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain RIIa PF02197.17 RLN98161.1 - 0.0034 17.0 0.0 0.0072 16.0 0.0 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit AAA_25 PF13481.6 RLN98162.1 - 0.0022 17.6 0.1 0.0072 15.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.7 RLN98162.1 - 0.061 12.2 0.0 0.094 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Y_phosphatase PF00102.27 RLN98162.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Asp PF00026.23 RLN98163.1 - 1.1e-56 192.5 0.6 1.8e-56 191.9 0.6 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RLN98163.1 - 2.7e-13 50.6 1.0 6.4e-06 26.5 0.2 2.8 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 RLN98163.1 - 0.00021 21.9 0.4 0.036 14.7 0.2 3.2 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 RLN98163.1 - 0.004 17.7 0.0 0.2 12.2 0.0 3.0 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 RLN98163.1 - 0.032 14.0 0.0 0.4 10.4 0.0 2.5 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Herpes_gE PF02480.16 RLN98164.1 - 0.0049 15.7 0.1 0.0054 15.5 0.1 1.0 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF4079 PF13301.6 RLN98164.1 - 0.0084 16.3 0.4 0.011 15.9 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) DUF202 PF02656.15 RLN98164.1 - 0.057 13.9 1.4 0.093 13.2 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) H_PPase PF03030.16 RLN98164.1 - 0.07 11.8 0.6 0.076 11.6 0.6 1.0 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase Amnionless PF14828.6 RLN98164.1 - 0.14 11.0 0.2 0.15 10.9 0.2 1.1 1 0 0 1 1 1 0 Amnionless DUF3377 PF11857.8 RLN98164.1 - 0.15 12.0 2.4 0.88 9.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) BatD PF13584.6 RLN98164.1 - 0.17 10.7 0.0 0.17 10.6 0.0 1.0 1 0 0 1 1 1 0 Oxygen tolerance EVC2_like PF12297.8 RLN98164.1 - 0.18 10.4 0.1 0.18 10.5 0.1 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein DUF4381 PF14316.6 RLN98164.1 - 0.19 11.9 1.2 0.25 11.6 0.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) LapA_dom PF06305.11 RLN98164.1 - 0.38 10.6 8.6 0.09 12.6 4.2 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4690 PF15756.5 RLN98164.1 - 0.65 10.6 2.3 0.65 10.6 1.7 1.3 1 1 0 1 1 1 0 Small Novel Rich in Cartilage EphA2_TM PF14575.6 RLN98164.1 - 0.93 10.4 3.2 1.5 9.8 1.6 1.9 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 RLN98164.1 - 3.6 7.7 6.2 2.8 8.1 1.9 2.0 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment MHYT PF03707.16 RLN98164.1 - 4.8 7.4 8.1 0.76 10.0 2.1 2.0 1 1 1 2 2 2 0 Bacterial signalling protein N terminal repeat DUF347 PF03988.12 RLN98164.1 - 9.1 6.6 12.3 0.079 13.2 2.8 2.5 3 1 0 3 3 2 0 Repeat of Unknown Function (DUF347) BatA PF07584.11 RLN98165.1 - 0.065 13.6 0.2 0.098 13.0 0.2 1.2 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal TPPK_C PF12555.8 RLN98165.1 - 0.12 12.4 1.8 0.2 11.7 1.8 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal DUF3551 PF12071.8 RLN98165.1 - 0.14 12.2 0.2 0.2 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3551) Pkinase PF00069.25 RLN98166.1 - 1e-48 166.0 0.0 1.5e-48 165.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN98166.1 - 3.2e-48 164.3 0.0 4.5e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 RLN98166.1 - 3.3e-09 36.9 14.2 0.0013 19.0 1.3 3.8 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN98166.1 - 1.1e-07 31.5 9.5 0.00048 19.8 0.3 3.8 1 1 3 4 4 4 4 Leucine rich repeat DUF4448 PF14610.6 RLN98166.1 - 0.0014 18.5 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) LRR_1 PF00560.33 RLN98166.1 - 0.004 17.5 8.2 8.8 7.3 0.9 5.5 5 0 0 5 5 5 1 Leucine Rich Repeat Adeno_E3_CR2 PF02439.15 RLN98166.1 - 0.025 14.4 0.5 0.044 13.6 0.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 APH PF01636.23 RLN98166.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN98166.1 - 0.2 10.4 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase LRR_6 PF13516.6 RLN98166.1 - 0.95 9.7 17.2 23 5.4 0.1 5.0 4 0 0 4 4 4 0 Leucine Rich repeat RMI1_N PF08585.12 RLN98168.1 - 1.5e-19 70.6 0.0 2.8e-17 63.2 0.0 2.5 1 1 1 2 2 2 2 RecQ mediated genome instability protein RMI1_C PF16099.5 RLN98168.1 - 1.9e-19 69.9 0.0 3.1e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold DUF908 PF06012.12 RLN98168.1 - 0.08 12.3 7.9 0.12 11.7 7.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Glucos_trans_II PF14264.6 RLN98168.1 - 0.22 10.8 7.1 0.38 10.1 7.1 1.3 1 0 0 1 1 1 0 Glucosyl transferase GtrII UPF0715 PF17094.5 RLN98168.1 - 3.3 8.3 11.9 0.063 13.8 1.1 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0715) Methyltransf_32 PF13679.6 RLN98169.1 - 7.5e-10 39.0 0.3 2.1e-06 27.8 0.6 2.4 2 0 0 2 2 2 2 Methyltransferase domain TRM13 PF05206.14 RLN98169.1 - 2.1e-07 30.7 0.0 1.2e-05 25.0 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase TRM13 MTS PF05175.14 RLN98169.1 - 0.043 13.3 0.0 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_25 PF13649.6 RLN98169.1 - 0.052 14.2 0.0 0.13 13.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 RLN98169.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.6 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G zf-TRM13_CCCH PF11722.8 RLN98169.1 - 0.55 10.0 2.8 0.9 9.4 1.1 2.4 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein CCDC106 PF15794.5 RLN98170.1 - 0.038 13.7 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 LPP PF04728.13 RLN98170.1 - 0.043 14.2 0.2 0.073 13.5 0.2 1.3 1 0 0 1 1 1 0 Lipoprotein leucine-zipper DUF2046 PF09755.9 RLN98170.1 - 0.13 11.5 0.2 0.18 11.0 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) EspB_PE PF18625.1 RLN98170.1 - 0.13 12.8 0.6 0.29 11.6 0.6 1.7 1 0 0 1 1 1 0 ESX-1 secreted protein B PE domain DUF3138 PF11336.8 RLN98170.1 - 0.14 10.8 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ndc1_Nup PF09531.10 RLN98170.1 - 5.8 5.5 6.3 7.4 5.1 6.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pkinase PF00069.25 RLN98171.1 - 2.2e-76 256.7 0.0 3.2e-76 256.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN98171.1 - 4.3e-34 118.0 0.0 5.7e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN98171.1 - 4.9e-06 25.6 0.0 2e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Shugoshin_C PF07557.11 RLN98171.1 - 2.4e-05 24.0 0.0 5.5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Shugoshin C terminus Kdo PF06293.14 RLN98171.1 - 4e-05 23.1 0.1 7.1e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RLN98171.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like bZIP_1 PF00170.21 RLN98171.1 - 0.024 14.8 0.5 0.74 10.0 0.2 2.5 2 0 0 2 2 2 0 bZIP transcription factor YrbL-PhoP_reg PF10707.9 RLN98171.1 - 0.033 13.7 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.11 RLN98171.1 - 0.05 12.6 0.1 0.082 11.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 RLN98171.1 - 0.06 13.3 0.1 0.26 11.2 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ank_3 PF13606.6 RLN98172.1 - 0.0012 19.1 0.0 24 5.9 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 RLN98172.1 - 0.0038 17.8 0.1 1.6 9.4 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN98172.1 - 0.0065 17.0 0.0 2.3 8.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) SMC_N PF02463.19 RLN98173.1 - 0.084 12.3 0.8 0.099 12.1 0.8 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain bZIP_2 PF07716.15 RLN98174.1 - 0.0059 16.7 5.6 0.0059 16.7 5.6 1.9 2 0 0 2 2 2 1 Basic region leucine zipper Pkinase_Tyr PF07714.17 RLN98175.1 - 2.1e-39 135.4 0.0 1.3e-35 122.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN98175.1 - 2.1e-37 128.9 0.0 3.1e-34 118.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Glyco_hydro_17 PF00332.18 RLN98177.1 - 1.9e-16 60.6 1.1 9.4e-09 35.3 0.1 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 PRR18 PF15671.5 RLN98177.1 - 9.7 6.0 8.3 3.4 7.5 3.7 2.2 3 0 0 3 3 3 0 Proline-rich protein family 18 FYVE PF01363.21 RLN98178.1 - 5.7e-05 23.2 10.1 0.00013 22.0 10.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RLN98178.1 - 0.0012 19.1 12.6 0.0036 17.5 12.6 2.0 1 1 0 1 1 1 1 FYVE-type zinc finger C1_1 PF00130.22 RLN98178.1 - 0.88 9.5 13.6 0.43 10.5 7.7 2.8 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HTH_48 PF17906.1 RLN98180.1 - 0.02 15.0 0.1 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 HTH domain in Mos1 transposase MBOAT PF03062.19 RLN98182.1 - 6.7e-39 134.2 1.1 1.2e-38 133.3 1.1 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Aminotran_4 PF01063.19 RLN98184.1 - 2.1 8.1 4.9 1.3 8.8 1.1 2.3 2 1 0 2 2 2 0 Amino-transferase class IV HTH_OrfB_IS605 PF12323.8 RLN98186.1 - 5.7e-07 28.9 0.0 1.3e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Abhydro_lipase PF04083.16 RLN98187.1 - 1.7e-16 59.5 0.0 3.2e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 RLN98187.1 - 4.3e-11 42.9 0.1 8.1e-11 42.0 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN98187.1 - 0.0039 16.5 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Aminotran_1_2 PF00155.21 RLN98188.1 - 2e-59 201.6 0.0 2.6e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PDT PF00800.18 RLN98188.1 - 9e-11 41.9 0.1 3.8e-10 39.9 0.1 1.9 1 1 1 2 2 2 1 Prephenate dehydratase Cys_Met_Meta_PP PF01053.20 RLN98188.1 - 0.0016 17.0 0.0 0.0036 15.9 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme 3HCDH_RFF PF18321.1 RLN98188.1 - 0.088 13.3 0.1 1.6 9.2 0.0 2.7 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain eIF3g PF12353.8 RLN98189.1 - 2.1e-30 105.7 0.7 3.1e-30 105.1 0.7 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 RLN98189.1 - 1.2e-19 69.9 0.0 2.1e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 RLN98189.1 - 0.036 14.3 2.1 9.5 6.4 0.0 3.1 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter BTB_2 PF02214.22 RLN98190.1 - 1.9e-12 47.4 0.1 7.5e-12 45.4 0.1 1.8 2 0 0 2 2 2 1 BTB/POZ domain Toxin_YhaV PF11663.8 RLN98190.1 - 0.046 13.8 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Toxin with endonuclease activity, of toxin-antitoxin system E1-E2_ATPase PF00122.20 RLN98191.1 - 4.6e-19 68.6 0.1 9.9e-19 67.5 0.0 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 RLN98191.1 - 1.5e-14 53.4 0.0 2.5e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus YDG PF18657.1 RLN98191.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 YDG domain Oxidored_FMN PF00724.20 RLN98192.1 - 6.9e-76 255.7 0.0 8.4e-76 255.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Hydrolase_4 PF12146.8 RLN98192.1 - 0.053 12.8 0.3 0.61 9.3 0.1 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Mu-like_Pro PF10123.9 RLN98194.1 - 0.077 12.5 1.5 0.11 12.1 1.5 1.2 1 0 0 1 1 1 0 Mu-like prophage I protein DUF1263 PF06882.12 RLN98194.1 - 0.52 10.4 3.5 27 4.9 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1263) NUC PF18510.1 RLN98195.1 - 0.027 14.9 0.4 0.05 14.0 0.4 1.4 1 0 0 1 1 1 0 Nuclease domain Csm1_N PF18504.1 RLN98195.1 - 0.21 12.0 5.7 3.3 8.1 0.5 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain RPN1_RPN2_N PF17781.1 RLN98197.1 - 3.1e-109 365.1 0.3 5.8e-109 364.2 0.1 1.5 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 RLN98197.1 - 5.2e-23 80.3 9.7 8e-05 22.9 0.1 7.2 7 0 0 7 7 7 5 Proteasome/cyclosome repeat MFS_2 PF13347.6 RLN98199.1 - 7.5e-11 41.2 13.6 7.5e-11 41.2 13.6 2.5 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.16 RLN98199.1 - 3.1e-10 39.5 47.1 1.5e-06 27.4 16.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_transf_28 PF03033.20 RLN98200.1 - 4.5e-07 30.0 0.0 1.8e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain Anophelin PF10731.9 RLN98200.1 - 0.14 12.0 0.5 0.35 10.8 0.3 1.7 1 1 1 2 2 2 0 Thrombin inhibitor from mosquito DKCLD PF08068.12 RLN98201.1 - 1.4e-06 28.3 0.1 2.5e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 DKCLD (NUC011) domain Phage_T7_tail PF03906.14 RLN98202.1 - 0.022 14.4 0.8 0.034 13.8 0.8 1.3 1 0 0 1 1 1 0 Phage T7 tail fibre protein PPC PF04151.15 RLN98202.1 - 0.039 15.1 2.5 0.1 13.7 2.5 1.7 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain S4 PF01479.25 RLN98203.1 - 4.7e-11 42.2 0.0 1.1e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 RLN98203.1 - 1.4e-08 35.5 1.5 2.5e-08 34.7 1.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain TelA PF05816.11 RLN98203.1 - 0.1 11.6 1.6 0.53 9.3 1.4 1.8 1 1 0 1 1 1 0 Toxic anion resistance protein (TelA) Glycophorin_A PF01102.18 RLN98204.1 - 0.022 15.0 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 Glycophorin A FBPase PF00316.20 RLN98204.1 - 0.037 13.5 0.1 0.053 13.0 0.1 1.1 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain Gram_pos_anchor PF00746.21 RLN98204.1 - 0.21 11.5 1.9 0.43 10.6 1.9 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif BT1 PF03092.16 RLN98205.1 - 6.1e-10 37.9 3.6 6.1e-10 37.9 3.6 2.7 2 2 0 2 2 2 2 BT1 family Cir_N PF10197.9 RLN98206.1 - 0.033 14.4 13.0 0.033 14.4 13.0 2.8 3 1 0 3 3 3 0 N-terminal domain of CBF1 interacting co-repressor CIR DUF5383 PF17355.2 RLN98206.1 - 0.13 12.6 2.9 0.19 12.1 2.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5383) Dak1 PF02733.17 RLN98207.1 - 9.4e-109 363.1 4.2 1.3e-108 362.6 4.2 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 RLN98207.1 - 1e-43 149.2 4.6 2.1e-43 148.3 4.6 1.5 1 0 0 1 1 1 1 DAK2 domain DUF3813 PF12758.7 RLN98208.1 - 0.0044 17.3 2.6 3.2 8.1 0.1 3.4 1 1 2 3 3 3 3 Protein of unknown function (DUF3813) Coat_F PF07875.12 RLN98208.1 - 0.009 16.2 5.4 4 7.8 0.3 4.1 4 0 0 4 4 4 1 Coat F domain DUF5304 PF17230.2 RLN98208.1 - 0.24 11.6 4.5 1.3 9.2 0.1 3.1 1 1 3 4 4 4 0 Family of unknown function (DUF5304) Pex19 PF04614.12 RLN98210.1 - 0.027 14.3 2.1 0.084 12.6 1.1 1.9 2 0 0 2 2 2 0 Pex19 protein family Nup54 PF13874.6 RLN98210.1 - 0.03 14.4 0.4 0.055 13.6 0.4 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DNA_ligase_A_N PF04675.14 RLN98210.1 - 0.13 12.6 1.0 0.16 12.3 0.2 1.6 2 0 0 2 2 2 0 DNA ligase N terminus Di19_C PF14571.6 RLN98210.1 - 0.16 12.5 0.8 0.52 10.9 0.4 2.0 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal DUF1336 PF07059.12 RLN98212.1 - 9.1e-61 205.8 0.0 2.6e-60 204.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1336) START PF01852.19 RLN98212.1 - 3.5e-13 49.4 0.2 6.7e-13 48.5 0.2 1.4 1 0 0 1 1 1 1 START domain PH PF00169.29 RLN98212.1 - 5.5e-07 30.1 0.3 7.1e-06 26.5 0.1 2.6 2 0 0 2 2 2 1 PH domain DUF3040 PF11239.8 RLN98212.1 - 8.7 6.7 9.4 0.58 10.5 3.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) ABC2_membrane PF01061.24 RLN98213.1 - 2e-56 190.7 60.3 4.7e-28 98.0 26.0 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 RLN98213.1 - 3.9e-15 56.6 0.0 5.9e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 RLN98213.1 - 1.1e-09 37.9 44.2 4.9e-06 25.9 3.7 3.9 2 2 1 3 3 3 2 ABC-2 family transporter protein PDR_assoc PF08370.11 RLN98213.1 - 2.4e-08 33.6 11.7 5.7e-06 26.0 0.1 3.7 3 0 0 3 3 3 2 Plant PDR ABC transporter associated PDR_CDR PF06422.12 RLN98213.1 - 1.6e-07 31.2 2.2 0.0012 18.7 0.1 3.8 3 0 0 3 3 3 2 CDR ABC transporter AAA_21 PF13304.6 RLN98213.1 - 0.0001 22.2 0.0 0.32 10.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN98213.1 - 0.0029 17.3 0.3 0.0065 16.2 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN98213.1 - 0.0053 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 RLN98213.1 - 0.0068 16.9 0.0 0.026 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN98213.1 - 0.013 15.9 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 RLN98213.1 - 0.035 14.4 0.1 0.11 12.8 0.1 1.9 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.19 RLN98213.1 - 0.14 11.5 0.1 11 5.3 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 RLN98213.1 - 0.17 11.4 0.1 0.28 10.7 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 RLN98213.1 - 0.2 11.2 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 RLN98213.1 - 0.2 10.4 0.1 0.32 9.7 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Pkinase_Tyr PF07714.17 RLN98216.1 - 8.9e-28 97.3 0.0 4.5e-17 62.2 0.0 3.4 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 RLN98216.1 - 2.3e-22 79.7 0.0 3.9e-14 52.7 0.0 3.1 2 1 1 3 3 3 2 Protein kinase domain AAA_lid_10 PF17872.1 RLN98216.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA lid domain EF-hand_7 PF13499.6 RLN98218.1 - 1.2e-11 44.8 1.2 4.6e-11 43.0 1.2 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN98218.1 - 2.6e-11 42.2 3.2 6.5e-05 22.2 0.7 2.9 2 0 0 2 2 2 2 EF hand Peptidase_M14 PF00246.24 RLN98218.1 - 6.1e-11 42.7 0.0 1.8e-10 41.1 0.0 1.7 1 1 0 1 1 1 1 Zinc carboxypeptidase EF-hand_6 PF13405.6 RLN98218.1 - 4.5e-08 32.4 0.2 0.0038 17.1 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain Pepdidase_M14_N PF18027.1 RLN98218.1 - 1.9e-07 31.4 0.2 8.1e-06 26.2 0.0 2.9 2 0 0 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain EF-hand_8 PF13833.6 RLN98218.1 - 6e-06 26.0 4.9 0.01 15.7 1.1 3.7 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 RLN98218.1 - 5.6e-05 22.5 0.4 0.093 12.3 0.1 2.9 2 0 0 2 2 2 2 EF hand AstE_AspA PF04952.14 RLN98218.1 - 0.0019 17.3 0.1 0.0032 16.6 0.1 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family K-box PF01486.17 RLN98218.1 - 0.085 13.0 0.7 0.33 11.2 0.7 2.0 1 0 0 1 1 1 0 K-box region FUSC PF04632.12 RLN98218.1 - 0.26 9.8 5.1 0.46 8.9 5.1 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family FUSC_2 PF13515.6 RLN98218.1 - 2.7 8.1 30.3 0.99 9.5 15.1 3.7 2 2 1 3 3 3 0 Fusaric acid resistance protein-like OrfB_IS605 PF01385.19 RLN98219.1 - 0.04 14.1 0.1 0.09 13.0 0.0 1.6 2 0 0 2 2 2 0 Probable transposase Scramblase PF03803.15 RLN98221.1 - 1.1e-11 44.5 0.0 0.00011 21.6 0.0 3.3 3 1 0 3 3 3 3 Scramblase PX PF00787.24 RLN98222.1 - 0.0067 16.4 0.0 0.0095 15.9 0.0 1.3 1 0 0 1 1 1 1 PX domain 5_nucleotid PF05761.14 RLN98223.1 - 2.8e-42 145.2 0.0 4.6e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 5' nucleotidase family RabGAP-TBC PF00566.18 RLN98223.1 - 0.0056 16.4 1.0 0.012 15.3 0.1 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain HA PF03457.14 RLN98224.1 - 4.2e-27 94.3 0.1 4.6e-07 30.1 0.0 6.4 5 0 0 5 5 5 4 Helicase associated domain Ank_5 PF13857.6 RLN98224.1 - 0.0002 21.6 0.0 0.00053 20.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN98224.1 - 0.00072 20.1 0.0 0.0017 18.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN98224.1 - 0.018 15.5 0.0 7.3 7.5 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 RLN98224.1 - 0.087 13.4 0.1 0.26 11.9 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Kinesin_assoc PF16183.5 RLN98224.1 - 1.1 9.4 18.1 0.22 11.7 5.3 2.7 1 1 1 2 2 2 0 Kinesin-associated Renin_r PF07850.14 RLN98225.1 - 5.2e-06 27.0 0.0 1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Renin receptor-like protein Aminotran_5 PF00266.19 RLN98226.1 - 3.6e-28 98.6 0.0 5.2e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V HHH_8 PF14716.6 RLN98227.1 - 0.033 14.5 0.0 0.087 13.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain ABC_membrane PF00664.23 RLN98229.1 - 1e-83 281.2 23.1 9.2e-46 156.7 6.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RLN98229.1 - 3.4e-54 183.1 0.2 2.4e-31 109.1 0.0 3.3 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 RLN98229.1 - 5.7e-12 45.5 2.8 0.0023 17.4 0.0 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RLN98229.1 - 4.1e-07 30.1 0.1 0.055 13.6 0.1 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_29 PF13555.6 RLN98229.1 - 4.7e-06 26.2 0.2 0.081 12.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN98229.1 - 0.00022 21.2 0.9 0.56 10.1 0.3 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 RLN98229.1 - 0.00081 19.3 0.1 2.8 7.7 0.0 3.7 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 RLN98229.1 - 0.00083 19.4 3.0 0.15 12.1 0.2 3.2 3 0 0 3 3 3 1 Dynamin family AAA_16 PF13191.6 RLN98229.1 - 0.0019 18.6 0.9 0.67 10.3 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 RLN98229.1 - 0.0024 18.4 0.0 4.9 7.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 RLN98229.1 - 0.0029 17.7 1.7 0.046 13.8 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain TsaE PF02367.17 RLN98229.1 - 0.012 15.6 0.2 2.4 8.2 0.0 3.2 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 RLN98229.1 - 0.016 15.4 1.0 3.4 7.9 0.1 3.0 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 RLN98229.1 - 0.023 14.3 0.1 0.3 10.6 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 RLN98229.1 - 0.033 13.4 0.2 2.1 7.4 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain cobW PF02492.19 RLN98229.1 - 0.054 13.1 1.0 1.1 8.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 RLN98229.1 - 0.067 12.2 0.6 4.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 RLN98229.1 - 0.076 13.2 0.4 5.4 7.3 0.1 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 RLN98229.1 - 0.091 12.7 1.3 3.6 7.5 0.0 2.8 3 0 0 3 3 3 0 NACHT domain AAA_30 PF13604.6 RLN98229.1 - 0.11 12.2 1.2 7.4 6.2 0.1 2.8 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 RLN98229.1 - 0.12 12.1 0.4 7.8 6.2 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_18 PF13238.6 RLN98229.1 - 0.15 12.6 1.4 9.8 6.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 RLN98229.1 - 0.26 11.5 0.8 3.7 7.7 0.2 2.6 2 0 0 2 2 2 0 AAA domain DUF3270 PF11674.8 RLN98229.1 - 1.5 9.0 7.8 0.089 13.0 0.3 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF3270) DUF2070 PF09843.9 RLN98229.1 - 5.6 5.1 8.9 16 3.6 8.9 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) LRR_6 PF13516.6 RLN98230.1 - 9.8e-23 78.2 20.5 4e-05 23.3 0.1 7.9 8 0 0 8 8 8 6 Leucine Rich repeat LRR_4 PF12799.7 RLN98230.1 - 1.9e-07 31.3 12.5 0.012 16.0 0.1 4.7 2 2 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN98230.1 - 0.00057 19.6 21.8 0.47 10.3 7.1 5.4 4 3 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 RLN98230.1 - 0.0042 17.4 8.6 3.9 8.4 0.0 5.3 5 1 0 5 5 5 1 Leucine Rich Repeat MT0933_antitox PF14013.6 RLN98231.1 - 0.15 12.4 30.5 0.3 11.4 2.9 4.7 2 1 3 5 5 5 0 MT0933-like antitoxin protein GTPase_binding PF09027.10 RLN98231.1 - 6.5 6.8 9.6 1e+02 3.0 0.1 4.1 2 1 1 4 4 4 0 GTPase binding MADF_DNA_bdg PF10545.9 RLN98232.1 - 0.13 12.6 0.1 0.26 11.7 0.1 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Cytochrome_CBB3 PF13442.6 RLN98233.1 - 0.11 12.8 0.0 0.71 10.2 0.0 2.1 2 1 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III TAFII55_N PF04658.13 RLN98234.1 - 2.1e-06 27.5 0.1 0.064 13.0 0.1 2.5 1 1 1 2 2 2 2 TAFII55 protein conserved region Cullin PF00888.22 RLN98235.1 - 6.5e-196 652.6 7.6 8.6e-196 652.2 7.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 RLN98235.1 - 1e-24 86.3 0.7 9.5e-24 83.2 0.8 2.6 2 0 0 2 2 2 1 Cullin protein neddylation domain TPR_17 PF13431.6 RLN98235.1 - 0.02 15.3 0.2 0.045 14.1 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat GlnD_UR_UTase PF08335.11 RLN98235.1 - 0.044 13.9 1.3 7.8 6.6 0.1 2.6 2 0 0 2 2 2 0 GlnD PII-uridylyltransferase Myosin_head PF00063.21 RLN98237.1 - 9.3e-222 738.0 0.0 1.8e-221 737.0 0.0 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 RLN98237.1 - 1.6e-18 64.7 48.8 0.0039 16.8 0.7 8.9 8 0 0 8 8 8 7 IQ calmodulin-binding motif AAA_22 PF13401.6 RLN98237.1 - 0.024 14.9 1.7 0.15 12.3 0.0 3.4 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.6 RLN98237.1 - 0.18 12.2 0.0 0.18 12.2 0.0 4.7 2 1 1 3 3 3 0 AAA ATPase domain GAIN_A PF18619.1 RLN98237.1 - 0.19 12.0 1.9 2.3 8.5 1.9 3.0 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Ephrin_rec_like PF07699.13 RLN98238.1 - 5.4e-16 58.1 30.9 1.2e-07 31.4 2.9 4.8 1 1 3 4 4 4 4 Putative ephrin-receptor like LapA_dom PF06305.11 RLN98238.1 - 0.069 13.0 1.6 0.21 11.4 0.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Use1 PF09753.9 RLN98239.1 - 8e-15 55.2 5.9 1.5e-14 54.4 5.9 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF4407 PF14362.6 RLN98239.1 - 5.6 6.2 11.1 20 4.4 11.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PGK PF00162.19 RLN98240.1 - 8.8e-157 521.9 0.0 1e-156 521.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Hydrolase PF00702.26 RLN98240.1 - 0.0025 18.1 0.4 0.38 11.0 0.1 2.9 1 1 2 3 3 3 2 haloacid dehalogenase-like hydrolase PrpR_N PF06506.11 RLN98240.1 - 0.065 12.8 1.6 2.9 7.4 0.2 2.8 2 1 0 2 2 2 0 Propionate catabolism activator Pkinase PF00069.25 RLN98241.1 - 1.3e-19 70.6 0.0 2.1e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF1752 PF08550.10 RLN98241.1 - 2.6e-08 33.5 1.2 6.3e-08 32.3 1.2 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Pkinase_Tyr PF07714.17 RLN98241.1 - 1.1e-06 28.2 0.0 1.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 RLN98241.1 - 0.00099 19.6 0.9 0.0021 18.6 0.9 1.6 1 0 0 1 1 1 1 PH domain eIF3g PF12353.8 RLN98241.1 - 0.086 13.2 0.1 0.086 13.2 0.1 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Pkinase PF00069.25 RLN98242.1 - 1e-19 71.0 0.0 5.3e-18 65.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Nup192 PF11894.8 RLN98243.1 - 2.3e-107 359.9 0.2 1.6e-92 310.7 0.0 2.3 2 0 0 2 2 2 2 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nup188 PF10487.9 RLN98243.1 - 0.00012 20.2 0.1 0.075 10.9 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 SPG48 PF14764.6 RLN98243.1 - 0.059 13.8 0.2 20 5.7 0.0 4.1 3 0 0 3 3 3 0 AP-5 complex subunit, vesicle trafficking 2OG-FeII_Oxy_3 PF13640.6 RLN98244.1 - 5.6e-09 36.8 0.0 1.3e-08 35.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribosomal_L2_C PF03947.18 RLN98245.1 - 5.5e-47 159.1 1.9 8.4e-47 158.5 1.9 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 RLN98245.1 - 4.5e-17 61.8 0.1 1.2e-16 60.4 0.1 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Pkinase PF00069.25 RLN98246.1 - 9.8e-61 205.4 0.0 1.3e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN98246.1 - 2e-25 89.6 0.0 2.7e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN98246.1 - 1.4e-05 24.6 0.0 5.1e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN98246.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Radial_spoke PF04712.12 RLN98247.1 - 4.4e-90 303.0 0.0 2.7e-53 181.6 0.0 2.2 1 1 1 2 2 2 2 Radial spokehead-like protein FANCF PF11107.8 RLN98247.1 - 0.075 12.2 0.0 0.16 11.1 0.0 1.5 2 0 0 2 2 2 0 Fanconi anemia group F protein (FANCF) SH3_9 PF14604.6 RLN98248.1 - 1.5e-15 56.7 0.3 3.5e-15 55.6 0.3 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RLN98248.1 - 8.2e-13 47.8 0.0 1.6e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RLN98248.1 - 3.8e-10 39.3 0.0 1e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Cullin PF00888.22 RLN98249.1 - 1.7e-21 76.5 0.0 2.7e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 RLN98249.1 - 1.4e-17 63.9 0.0 9e-17 61.3 0.1 2.4 3 0 0 3 3 3 1 Anaphase promoting complex (APC) subunit 2 pKID PF02173.17 RLN98249.1 - 0.11 12.0 0.1 0.31 10.6 0.1 1.8 1 0 0 1 1 1 0 pKID domain HTH_20 PF12840.7 RLN98249.1 - 0.15 12.2 1.6 0.6 10.2 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain RNA_polI_A34 PF08208.11 RLN98250.1 - 1.9 8.6 30.9 0.085 12.9 2.5 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 BK_channel_a PF03493.18 RLN98251.1 - 5.2e-29 100.3 0.0 4.2e-25 87.8 0.0 2.6 2 0 0 2 2 2 2 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 RLN98251.1 - 3.5e-14 52.5 3.1 7.1e-14 51.5 3.1 1.5 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 RLN98251.1 - 5.3e-14 52.0 7.0 8.9e-14 51.3 7.0 1.3 1 0 0 1 1 1 1 Ion transport protein TrkA_C PF02080.21 RLN98251.1 - 0.013 15.3 0.0 0.31 10.9 0.0 2.8 2 0 0 2 2 2 0 TrkA-C domain TrkA_N PF02254.18 RLN98251.1 - 0.043 14.1 0.2 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain tRNA-synt_2 PF00152.20 RLN98252.1 - 1.3e-80 270.8 0.0 1.7e-80 270.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RLN98252.1 - 6.9e-10 38.8 0.1 1.2e-09 38.0 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 RLN98252.1 - 1.2e-08 34.8 0.2 5.9e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Pkinase PF00069.25 RLN98253.1 - 9.3e-71 238.3 0.0 1.3e-70 237.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN98253.1 - 9.9e-39 133.2 0.0 1.4e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN98253.1 - 1.2e-07 31.3 0.1 2e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN98253.1 - 7e-06 25.1 0.0 1.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN98253.1 - 0.0002 20.8 0.1 0.082 12.2 0.0 2.5 2 1 0 2 2 2 2 Kinase-like F420_oxidored PF03807.17 RLN98253.1 - 0.0031 18.1 0.0 0.015 15.9 0.0 2.2 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent LRV PF01816.17 RLN98253.1 - 4.1 8.0 6.2 1 9.9 1.0 2.7 2 0 0 2 2 2 0 Leucine rich repeat variant SCP2 PF02036.17 RLN98255.1 - 1.7e-48 163.2 9.4 2.9e-25 88.7 1.7 2.1 2 0 0 2 2 2 2 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 RLN98255.1 - 9.5e-15 55.0 3.8 3e-08 34.0 0.5 2.1 2 0 0 2 2 2 2 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 RLN98255.1 - 0.016 15.6 0.0 4.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Sterol carrier protein domain ORC5_C PF14630.6 RLN98256.1 - 1.2e-34 120.1 0.4 1.8e-34 119.6 0.4 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 RLN98256.1 - 8.9e-06 26.2 2.1 2.7e-05 24.6 2.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RLN98256.1 - 2.4e-05 24.6 0.0 5.8e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain CD36 PF01130.21 RLN98257.1 - 1.9e-35 122.3 0.0 3.7e-34 118.0 0.0 2.4 1 1 0 1 1 1 1 CD36 family DUF3512 PF12024.8 RLN98257.1 - 0.11 12.0 0.4 0.2 11.1 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) Ctr PF04145.15 RLN98258.1 - 0.83 10.3 6.8 7.6 7.2 6.8 2.5 1 1 0 1 1 1 0 Ctr copper transporter family DUF3704 PF12488.8 RLN98258.1 - 0.99 9.1 4.2 0.24 11.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3704) Ank_2 PF12796.7 RLN98259.1 - 7.2e-28 97.0 17.9 1.2e-07 32.2 0.0 5.5 3 1 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN98259.1 - 5.5e-22 77.8 14.0 1.2e-07 32.1 0.2 7.7 3 3 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN98259.1 - 1.5e-18 66.6 15.1 0.16 12.4 0.1 10.1 4 3 6 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN98259.1 - 3.1e-17 60.9 9.4 1.2 9.9 0.0 11.2 10 2 2 12 12 12 5 Ankyrin repeat Ank PF00023.30 RLN98259.1 - 9.8e-06 25.8 5.3 7.9 7.1 0.0 8.1 6 2 2 8 8 8 1 Ankyrin repeat DUF5049 PF16468.5 RLN98259.1 - 0.00018 21.4 8.2 8.6 6.3 0.0 7.5 5 3 4 9 9 9 1 Domain of unknown function (DUF5049) DUF3322 PF11795.8 RLN98259.1 - 0.025 14.6 0.6 1 9.4 0.0 3.4 2 2 3 5 5 5 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) SMC_hinge PF06470.13 RLN98260.1 - 2.4e-24 85.9 1.4 2.6e-23 82.5 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.19 RLN98260.1 - 6e-24 84.7 11.9 6e-24 84.7 11.9 3.1 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 RLN98260.1 - 1.3e-11 44.9 15.4 1.3e-11 44.9 15.3 3.1 2 2 0 2 2 1 1 AAA ATPase domain AAA_23 PF13476.6 RLN98260.1 - 1.1e-08 35.9 28.0 1.1e-08 35.9 28.0 6.4 2 2 3 5 5 2 1 AAA domain AAA_21 PF13304.6 RLN98260.1 - 4.8e-06 26.6 0.0 4.8e-06 26.6 0.0 2.8 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN98260.1 - 2.6e-05 23.9 0.0 5.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 RLN98260.1 - 0.0011 17.9 14.2 0.0011 17.9 14.2 6.9 3 2 4 7 7 6 2 Spc7 kinetochore protein DUF4140 PF13600.6 RLN98260.1 - 0.012 16.0 0.3 0.012 16.0 0.3 9.9 4 3 3 8 8 6 0 N-terminal domain of unknown function (DUF4140) TMF_TATA_bd PF12325.8 RLN98260.1 - 0.012 15.8 6.5 0.012 15.8 6.5 8.8 3 2 4 8 8 7 0 TATA element modulatory factor 1 TATA binding DUF5320 PF17253.2 RLN98260.1 - 0.25 12.5 0.1 0.25 12.5 0.1 7.0 4 2 5 9 9 7 0 Family of unknown function (DUF5320) Baculo_PEP_C PF04513.12 RLN98260.1 - 1.7 8.7 24.8 0.14 12.2 1.3 4.5 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus SAM_1 PF00536.30 RLN98261.1 - 8.1e-08 32.6 0.1 1.4e-07 31.8 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RLN98261.1 - 5.1e-07 29.7 0.0 9e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Sigma70_ner PF04546.13 RLN98261.1 - 1.6 8.6 11.8 2 8.2 3.8 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region RNase_H2_suC PF08615.11 RLN98261.1 - 1.7 8.8 6.7 0.89 9.7 0.3 2.2 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Sec20 PF03908.13 RLN98262.1 - 4.2e-07 29.8 0.3 7.3e-07 29.0 0.3 1.4 1 0 0 1 1 1 1 Sec20 V-SNARE_C PF12352.8 RLN98262.1 - 2.4e-05 24.6 1.7 5.3e-05 23.4 1.7 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus KxDL PF10241.9 RLN98262.1 - 0.0035 17.6 1.1 0.009 16.3 1.1 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein Peptidase_C25 PF01364.18 RLN98262.1 - 0.0071 15.6 0.0 0.0095 15.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C25 Proteasome PF00227.26 RLN98263.1 - 6.9e-30 103.9 0.0 1.1e-29 103.3 0.0 1.3 1 1 0 1 1 1 1 Proteasome subunit Tim17 PF02466.19 RLN98264.1 - 1.2e-29 102.9 5.5 1.4e-29 102.7 5.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4235 PF14019.6 RLN98264.1 - 0.0035 17.4 0.0 0.031 14.4 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4235) UCR_UQCRX_QCR9 PF05365.12 RLN98265.1 - 2.6e-16 59.3 1.0 3.8e-16 58.8 1.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like SGS PF05002.15 RLN98265.1 - 2.5 8.3 7.9 4.7 7.4 7.9 1.5 1 0 0 1 1 1 0 SGS domain Nop14 PF04147.12 RLN98265.1 - 8.7 4.4 13.7 9.8 4.2 13.7 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_Rpb4 PF03874.16 RLN98266.1 - 9.3e-16 58.3 0.4 9.3e-16 58.3 0.4 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb4 PRA-CH PF01502.18 RLN98267.1 - 6.9e-26 89.9 0.1 1.4e-25 88.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 RLN98267.1 - 2.2e-10 40.8 0.2 4.9e-10 39.7 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Tctex-1 PF03645.13 RLN98268.1 - 7.3e-24 84.0 0.1 8.3e-24 83.8 0.1 1.0 1 0 0 1 1 1 1 Tctex-1 family Herpes_UL4 PF03277.13 RLN98268.1 - 0.0082 15.8 0.1 0.0085 15.7 0.1 1.1 1 0 0 1 1 1 1 Herpesvirus UL4 family UQ_con PF00179.26 RLN98269.1 - 1.1e-42 145.0 0.0 1.2e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RLN98269.1 - 6.7e-05 22.6 0.0 8.5e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RRM_1 PF00076.22 RLN98270.1 - 3.9e-39 132.3 0.5 3.8e-17 61.9 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 RLN98270.1 - 7.9e-14 52.5 0.0 7.9e-14 52.5 0.0 2.4 3 0 0 3 3 3 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 RLN98270.1 - 0.0087 15.9 0.0 11 6.0 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 RLN98270.1 - 0.029 14.5 0.1 1.4 9.1 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif GREB1 PF15782.5 RLN98270.1 - 1.5 5.9 3.7 2 5.4 3.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TPR_1 PF00515.28 RLN98271.1 - 4.5e-11 42.1 1.8 0.00038 20.2 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN98271.1 - 4.5e-11 42.0 0.5 0.043 13.9 0.0 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN98271.1 - 1.1e-05 25.3 1.5 7.7e-05 22.7 0.1 2.8 2 1 1 3 3 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 RLN98271.1 - 5.5e-05 23.2 4.4 5.5e-05 23.2 4.4 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Arm PF00514.23 RLN98271.1 - 0.00036 20.5 9.7 2.2 8.4 0.0 6.0 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat TPR_19 PF14559.6 RLN98271.1 - 0.00045 20.7 1.4 0.00045 20.7 1.4 3.8 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 RLN98271.1 - 0.00094 19.8 5.8 0.034 14.8 0.4 4.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN98271.1 - 0.012 15.8 3.3 0.44 10.9 0.4 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 RLN98271.1 - 0.026 14.9 0.5 3 8.4 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat CorA PF01544.18 RLN98271.1 - 0.1 11.9 0.1 0.41 9.9 0.1 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein TPR_8 PF13181.6 RLN98271.1 - 0.1 12.9 0.8 32 5.1 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 RLN98271.1 - 0.11 13.4 18.7 0.094 13.6 0.8 5.9 4 1 1 5 5 4 0 Tetratricopeptide repeat HEAT_2 PF13646.6 RLN98271.1 - 0.44 11.0 0.0 0.44 11.0 0.0 5.7 5 1 1 6 6 6 0 HEAT repeats TPR_11 PF13414.6 RLN98271.1 - 0.58 9.9 2.3 33 4.3 0.0 3.0 3 0 0 3 3 3 0 TPR repeat AMP-binding PF00501.28 RLN98272.1 - 1.5e-80 270.9 0.1 1.7e-80 270.7 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN98272.1 - 5.3e-16 59.4 0.0 1.7e-15 57.7 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_M6 PF05547.11 RLN98273.1 - 0.0017 16.8 2.3 0.0025 16.2 2.3 1.2 1 0 0 1 1 1 1 Immune inhibitor A peptidase M6 Reprolysin_4 PF13583.6 RLN98273.1 - 0.0063 16.2 1.1 0.0092 15.6 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 RLN98273.1 - 0.0085 16.3 2.3 0.024 14.8 0.0 2.5 2 1 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 RLN98273.1 - 0.11 13.1 0.0 0.31 11.6 0.0 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like MCLC PF05934.11 RLN98273.1 - 0.64 8.7 3.0 0.88 8.2 3.0 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) CENP-B_N PF04218.13 RLN98274.1 - 1.4e-05 24.6 0.2 2.7e-05 23.7 0.2 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 RLN98274.1 - 0.0027 17.5 0.6 0.0027 17.5 0.6 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 RLN98274.1 - 0.015 15.4 1.5 0.023 14.8 0.4 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 RLN98274.1 - 0.022 14.6 1.1 0.15 11.9 0.0 2.5 2 2 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT KORA PF16509.5 RLN98274.1 - 0.037 14.3 0.3 0.092 13.0 0.0 1.9 2 1 0 2 2 2 0 TrfB plasmid transcriptional repressor HTH_7 PF02796.15 RLN98274.1 - 0.069 13.2 0.1 0.19 11.8 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_3 PF01381.22 RLN98274.1 - 0.12 12.4 0.2 0.31 11.1 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix GP79 PF17463.2 RLN98275.1 - 0.027 14.5 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Gene product 79 UPRTase PF14681.6 RLN98275.1 - 0.16 11.4 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Tfb2 PF03849.14 RLN98276.1 - 1.5e-103 346.6 0.2 7.6e-84 281.7 0.0 2.0 1 1 1 2 2 2 2 Transcription factor Tfb2 Tfb2_C PF18307.1 RLN98276.1 - 3.2e-22 78.7 0.2 9.4e-22 77.2 0.2 1.9 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 RLN98276.1 - 0.012 15.8 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Kelch_1 PF01344.25 RLN98277.1 - 2e-40 136.1 4.0 4.1e-09 35.9 0.0 5.2 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 RLN98277.1 - 1.5e-38 129.8 9.1 2.2e-09 37.2 0.1 5.0 3 2 2 5 5 5 5 Kelch motif Kelch_3 PF13415.6 RLN98277.1 - 4.7e-35 119.2 11.7 1.1e-09 38.4 0.1 5.1 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.6 RLN98277.1 - 1.1e-34 118.2 13.6 1.5e-10 40.9 0.3 5.1 4 1 1 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RLN98277.1 - 9.2e-30 102.1 11.7 2e-06 27.6 0.2 5.4 5 1 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 RLN98277.1 - 1.3e-28 97.9 6.2 2.9e-06 27.0 0.1 5.1 5 0 0 5 5 5 5 Kelch motif PH PF00169.29 RLN98278.1 - 4.3e-05 24.0 0.2 9.5e-05 22.9 0.2 1.6 1 1 0 1 1 1 1 PH domain AhpC-TSA PF00578.21 RLN98279.1 - 7.1e-37 126.1 0.0 9.8e-37 125.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RLN98279.1 - 1.1e-16 60.9 0.0 1.5e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 RLN98279.1 - 1.3e-13 50.5 0.0 2.2e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 RLN98279.1 - 0.08 12.9 0.1 0.28 11.1 0.1 1.8 2 0 0 2 2 2 0 SCO1/SenC Acyl_transf_3 PF01757.22 RLN98280.1 - 1.3e-12 47.4 34.8 1.8e-12 47.0 34.8 1.2 1 0 0 1 1 1 1 Acyltransferase family Asparaginase_2 PF01112.18 RLN98281.1 - 1.1e-37 129.7 2.2 1.9e-30 106.0 0.3 3.1 2 1 0 2 2 2 2 Asparaginase dCMP_cyt_deam_1 PF00383.23 RLN98282.1 - 1.4e-17 63.5 0.2 2.9e-17 62.4 0.0 1.6 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region Elicitin PF00964.17 RLN98282.1 - 4.1e-17 62.1 0.3 8.8e-17 61.0 0.3 1.6 1 0 0 1 1 1 1 Elicitin MafB19-deam PF14437.6 RLN98282.1 - 1e-15 57.7 0.0 1.6e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 RLN98282.1 - 0.00042 20.4 0.0 0.0013 18.8 0.0 1.8 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 RLN98282.1 - 0.00098 19.2 0.4 0.24 11.5 0.2 2.6 1 1 1 2 2 2 2 Bd3614-like deaminase NAD1 PF18778.1 RLN98282.1 - 0.012 15.7 0.0 0.031 14.4 0.0 1.6 2 0 0 2 2 2 0 Novel AID APOBEC clade 1 NAD2 PF18782.1 RLN98282.1 - 0.046 13.8 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC2 PF18772.1 RLN98282.1 - 0.064 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 APOBEC2 APOBEC_N PF08210.11 RLN98282.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.5 1 1 0 1 1 1 0 APOBEC-like N-terminal domain DUF1744 PF08490.12 RLN98283.1 - 2.3e-97 326.1 0.0 3.6e-97 325.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 RLN98283.1 - 1.5e-71 241.3 0.0 2.3e-71 240.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 RLN98283.1 - 1.8e-15 56.6 0.3 2.6e-13 49.5 0.3 3.2 3 0 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 RLN98283.1 - 3e-08 33.6 0.1 7.6e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 RLN98283.1 - 5.4e-07 29.7 0.1 2.4e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 RNase_H superfamily Cutinase PF01083.22 RLN98284.1 - 4.6e-43 147.2 2.2 5.7e-43 146.9 2.2 1.1 1 0 0 1 1 1 1 Cutinase DUF4643 PF15485.6 RLN98286.1 - 0.016 15.1 0.7 0.016 15.1 0.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4643) Hexapep PF00132.24 RLN98287.1 - 1.9e-13 49.5 6.8 1.1e-10 40.8 4.1 3.4 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 RLN98287.1 - 6e-12 45.6 0.0 1.4e-11 44.4 0.0 1.6 2 0 0 2 2 2 1 Maltose acetyltransferase Hexapep_2 PF14602.6 RLN98287.1 - 6.6e-10 38.6 8.5 1.4e-09 37.5 2.9 3.2 2 1 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Pkinase_Tyr PF07714.17 RLN98289.1 - 1.3e-54 185.2 0.0 8.3e-39 133.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RLN98289.1 - 4.2e-48 164.0 0.0 4.4e-26 91.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain zf-ribbon_3 PF13248.6 RLN98289.1 - 8.5e-05 21.8 1.5 0.00016 21.0 1.5 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 RLN98289.1 - 0.00042 20.3 0.5 0.00092 19.2 0.5 1.5 1 0 0 1 1 1 1 Double zinc ribbon APH PF01636.23 RLN98289.1 - 0.00055 19.9 0.0 0.12 12.2 0.0 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RLN98289.1 - 0.0011 18.3 0.0 0.029 13.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 RLN98289.1 - 0.0087 15.4 0.0 0.058 12.7 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family UPF0547 PF10571.9 RLN98289.1 - 0.056 13.5 6.1 0.12 12.5 6.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Seadorna_VP7 PF07387.11 RLN98289.1 - 0.14 11.1 0.0 13 4.7 0.0 2.4 2 0 0 2 2 2 0 Seadornavirus VP7 RIO1 PF01163.22 RLN98289.1 - 0.21 11.2 0.0 15 5.1 0.0 2.3 2 0 0 2 2 2 0 RIO1 family LRR_12 PF18837.1 RLN98290.1 - 0.016 14.8 1.6 0.066 12.9 0.2 2.1 2 0 0 2 2 2 0 Leucine-rich repeat Kri1_C PF12936.7 RLN98291.1 - 2.9e-26 91.5 4.7 2.9e-26 91.5 4.7 2.9 3 0 0 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.12 RLN98291.1 - 5.2e-22 78.4 10.0 5.2e-22 78.4 10.0 4.5 4 1 0 5 5 5 1 KRI1-like family cNMP_binding PF00027.29 RLN98292.1 - 0.0007 19.6 0.2 0.36 10.9 0.0 3.2 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain FYVE PF01363.21 RLN98293.1 - 1.8e-17 63.3 10.8 3.3e-17 62.4 10.8 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF_2 PF13185.6 RLN98293.1 - 3e-07 30.8 0.2 1.2e-06 28.8 0.0 2.1 3 0 0 3 3 3 1 GAF domain GAF PF01590.26 RLN98293.1 - 0.0016 19.0 0.0 0.0063 17.2 0.0 2.0 2 0 0 2 2 2 1 GAF domain FYVE_2 PF02318.16 RLN98293.1 - 0.0034 17.6 7.2 0.007 16.6 7.2 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger DUF4428 PF14471.6 RLN98293.1 - 5.3 7.1 8.8 16 5.5 2.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) PilJ PF13675.6 RLN98294.1 - 0.028 14.5 5.7 0.056 13.5 0.3 2.5 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Myb_DNA-binding PF00249.31 RLN98298.1 - 2.5e-06 27.6 0.1 4.6e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF1127 PF06568.11 RLN98298.1 - 4.2 7.2 6.6 8.6 6.2 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) tRNA_edit PF04073.15 RLN98300.1 - 1.6e-06 28.2 0.1 0.0058 16.7 0.0 2.5 2 1 1 3 3 3 2 Aminoacyl-tRNA editing domain p450 PF00067.22 RLN98301.1 - 4.7e-15 55.3 0.0 5.6e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Metallophos_C PF14008.6 RLN98303.1 - 9.7e-17 61.6 0.2 1.4e-16 61.1 0.2 1.3 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C LIP PF03583.14 RLN98303.1 - 0.0057 16.0 0.0 0.0067 15.8 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Pur_ac_phosph_N PF16656.5 RLN98304.1 - 5.8e-17 62.0 11.9 7.7e-17 61.7 11.9 1.2 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 RLN98304.1 - 0.0087 16.6 1.4 0.013 16.0 1.4 1.4 1 1 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain HSP90 PF00183.18 RLN98306.1 - 1.3e-51 176.1 0.1 1.4e-51 176.0 0.1 1.0 1 0 0 1 1 1 1 Hsp90 protein TRIQK PF15168.6 RLN98306.1 - 0.028 14.3 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family IBN_N PF03810.19 RLN98307.1 - 1.1e-08 34.8 0.0 3.1e-07 30.2 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain RIX1 PF08167.12 RLN98307.1 - 3.5e-05 23.6 0.1 0.022 14.5 0.0 3.7 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis Cse1 PF08506.10 RLN98307.1 - 0.0002 20.3 0.1 0.0015 17.4 0.1 2.4 1 1 0 1 1 1 1 Cse1 Xpo1 PF08389.12 RLN98307.1 - 0.0051 16.9 2.1 0.16 12.0 2.1 3.3 2 1 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.22 RLN98307.1 - 5.4 7.6 6.5 2.9e+02 2.2 0.0 6.0 6 0 0 6 6 6 0 HEAT repeat SHMT PF00464.19 RLN98308.1 - 6.7e-200 663.8 0.0 7.9e-200 663.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 RLN98308.1 - 0.006 15.8 0.0 0.019 14.2 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II Methyltransf_16 PF10294.9 RLN98309.1 - 1.2e-29 103.3 0.1 1.8e-29 102.7 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 RLN98309.1 - 0.00015 21.3 0.2 0.00022 20.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 RLN98309.1 - 0.0084 15.7 0.1 0.014 14.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 RLN98309.1 - 0.053 13.2 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Glucan_synthase PF02364.15 RLN98310.1 - 1.5e-99 334.3 0.0 7.6e-80 269.2 0.0 2.6 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 RLN98310.1 - 9.2e-29 100.4 0.5 8.5e-28 97.3 0.5 2.3 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 MCM PF00493.23 RLN98311.1 - 1.7e-86 289.0 0.2 3.9e-86 287.8 0.0 1.6 2 0 0 2 2 2 1 MCM P-loop domain MCM_lid PF17855.1 RLN98311.1 - 1.9e-26 92.3 0.6 1.9e-26 92.3 0.6 1.9 2 0 0 2 2 2 1 MCM AAA-lid domain AAA_5 PF07728.14 RLN98311.1 - 1.7e-09 37.8 0.0 4.2e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 RLN98311.1 - 4.2e-09 36.1 0.2 4.9e-06 26.1 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RLN98311.1 - 4.6e-05 23.3 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RLN98311.1 - 6e-05 22.8 0.0 0.0011 18.7 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 RLN98311.1 - 0.002 18.5 0.0 0.006 17.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 RLN98311.1 - 0.0046 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 RLN98311.1 - 0.0098 16.3 1.2 0.068 13.6 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 RLN98311.1 - 0.022 14.1 0.5 0.065 12.6 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family MCM_OB PF17207.3 RLN98311.1 - 0.056 13.3 0.1 0.096 12.5 0.1 1.4 1 0 0 1 1 1 0 MCM OB domain AAA_22 PF13401.6 RLN98311.1 - 0.062 13.6 0.7 0.72 10.1 0.0 2.9 2 2 3 5 5 5 0 AAA domain AAA_19 PF13245.6 RLN98311.1 - 0.088 13.1 1.0 4.2 7.7 0.0 2.7 2 1 1 3 3 3 0 AAA domain NTPase_1 PF03266.15 RLN98311.1 - 0.091 12.7 0.4 6.5 6.6 0.1 2.3 1 1 1 2 2 2 0 NTPase MCM_OB PF17207.3 RLN98312.1 - 1.3e-10 41.2 1.7 2e-10 40.6 1.7 1.3 1 0 0 1 1 1 1 MCM OB domain Cobl PF09469.10 RLN98312.1 - 0.09 13.0 1.3 0.18 12.1 1.3 1.5 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain CTP_transf_3 PF02348.19 RLN98312.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Cytidylyltransferase PH PF00169.29 RLN98313.1 - 1e-12 48.5 0.1 1.2e-12 48.2 0.1 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN98313.1 - 5.1e-06 26.9 0.2 0.00035 21.0 0.2 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 RLN98313.1 - 0.00011 22.4 0.3 0.00029 21.0 0.3 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 RLN98313.1 - 0.015 15.1 0.1 0.036 13.9 0.0 1.6 1 1 1 2 2 2 0 Pleckstrin homology domain PH_9 PF15410.6 RLN98313.1 - 0.029 14.7 0.0 1.7 9.0 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain PH_3 PF14593.6 RLN98313.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.7 1 1 0 1 1 1 0 PH domain FH2 PF02181.23 RLN98314.1 - 2.4e-93 313.3 0.6 2.4e-93 313.3 0.6 3.1 3 1 1 4 4 4 1 Formin Homology 2 Domain CCDC53 PF10152.9 RLN98314.1 - 2.8e-37 128.5 26.7 8.5e-13 49.0 9.3 5.7 5 1 0 5 5 5 3 Subunit CCDC53 of WASH complex FYVE PF01363.21 RLN98314.1 - 5.6e-09 36.0 11.8 1.4e-08 34.7 10.6 2.1 2 0 0 2 2 2 1 FYVE zinc finger zinc_ribbon_2 PF13240.6 RLN98314.1 - 2.4e-06 27.1 5.7 2.7e-06 26.9 1.6 2.6 2 0 0 2 2 2 1 zinc-ribbon domain FYVE_2 PF02318.16 RLN98314.1 - 3.7e-05 23.9 3.6 3.7e-05 23.9 3.6 3.1 4 0 0 4 4 4 1 FYVE-type zinc finger DZR PF12773.7 RLN98314.1 - 0.00043 20.2 0.2 0.00043 20.2 0.2 3.2 2 1 0 2 2 2 1 Double zinc ribbon HXXSHH PF07586.11 RLN98314.1 - 0.13 11.8 2.9 1.3 8.5 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) zf-piccolo PF05715.13 RLN98314.1 - 1.1 9.5 10.7 0.46 10.7 5.3 2.5 2 0 0 2 2 2 0 Piccolo Zn-finger zinc_ribbon_15 PF17032.5 RLN98314.1 - 2 9.2 10.3 50 4.7 10.3 2.7 1 1 0 1 1 1 0 zinc-ribbon family zf-Nse PF11789.8 RLN98315.1 - 1.2e-05 25.1 0.4 2.3e-05 24.1 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 RLN98315.1 - 5.3e-05 23.0 0.8 9.2e-05 22.2 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN98315.1 - 0.0033 17.4 0.3 0.0068 16.4 0.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 RLN98315.1 - 0.004 17.5 0.7 0.0066 16.8 0.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 RLN98315.1 - 0.019 15.1 0.7 0.046 13.9 0.7 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING ATP11 PF06644.11 RLN98316.1 - 7.8e-25 88.2 0.2 7.8e-25 88.2 0.2 2.3 2 0 0 2 2 2 1 ATP11 protein E2F_TDP PF02319.20 RLN98316.1 - 3.4e-19 68.7 4.6 1.4e-08 34.7 1.1 3.1 2 2 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain CDC45 PF02724.14 RLN98316.1 - 1.2 7.3 8.8 1.9 6.7 8.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Peptidase_M16_M PF16187.5 RLN98317.1 - 2.4e-61 207.5 0.1 6.3e-59 199.5 0.0 2.8 2 1 1 3 3 3 2 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 RLN98317.1 - 2.2e-33 115.3 0.0 1.1e-32 113.1 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 RLN98317.1 - 2.8e-22 79.6 0.0 5.6e-08 33.0 0.0 4.0 3 1 1 4 4 4 3 Peptidase M16 inactive domain DUF2824 PF11039.8 RLN98317.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) GMP_PDE_delta PF05351.11 RLN98318.1 - 2.6e-09 37.3 0.0 1.8e-07 31.4 0.0 2.0 2 0 0 2 2 2 2 GMP-PDE, delta subunit TF_Zn_Ribbon PF08271.12 RLN98320.1 - 8.7e-05 22.0 1.2 8.7e-05 22.0 1.2 3.2 3 1 0 3 3 3 1 TFIIB zinc-binding zf-C2H2_jaz PF12171.8 RLN98320.1 - 0.00024 21.3 1.3 0.23 11.8 0.0 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 RLN98320.1 - 0.00092 19.5 7.4 0.079 13.4 0.1 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_9 PF16293.5 RLN98320.1 - 0.0015 18.3 0.8 1 9.2 0.1 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (1 copy) zf-C2H2_4 PF13894.6 RLN98320.1 - 0.0026 18.5 8.3 0.054 14.4 0.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger Rad50_zn_hook PF04423.14 RLN98320.1 - 0.0029 17.4 0.8 1.9 8.4 0.1 3.0 3 0 0 3 3 3 2 Rad50 zinc hook motif zf-Di19 PF05605.12 RLN98320.1 - 0.014 15.7 2.9 0.58 10.5 0.1 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 RLN98320.1 - 0.014 15.8 1.1 5.4 7.6 0.1 3.2 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-met PF12874.7 RLN98320.1 - 0.025 15.0 3.3 1.2 9.7 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RLN98320.1 - 0.047 13.7 0.1 0.047 13.7 0.1 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 RLN98320.1 - 0.16 12.7 0.9 11 6.9 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon family zf-C2H2_2 PF12756.7 RLN98320.1 - 0.8 10.1 3.2 6.7 7.1 0.1 2.8 3 0 0 3 3 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 RLN98320.1 - 5.9 7.5 18.1 0.34 11.4 0.4 4.0 5 0 0 5 5 4 0 Zinc-finger double domain zf-Paramyx-P PF13008.7 RLN98321.1 - 0.043 13.3 0.5 0.09 12.2 0.5 1.4 1 0 0 1 1 1 0 Zinc-binding domain of Paramyxoviridae V protein FPL PF09758.9 RLN98322.1 - 1.3e-41 142.1 0.0 3.6e-41 140.6 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein SR-25 PF10500.9 RLN98322.1 - 3.4 7.2 13.9 8.1 6.0 13.9 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Palm_thioest PF02089.15 RLN98323.1 - 6.4e-46 157.2 0.1 7.8e-46 156.9 0.1 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.18 RLN98323.1 - 0.00016 21.3 0.0 0.00034 20.2 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 2) DUF676 PF05057.14 RLN98323.1 - 0.00092 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 RLN98323.1 - 0.0036 17.0 0.1 0.0077 15.9 0.0 1.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN98323.1 - 0.025 15.2 0.0 0.029 15.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 RLN98323.1 - 0.032 13.8 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase RL11D PF11088.8 RLN98323.1 - 0.054 13.8 1.9 0.33 11.3 0.1 2.5 2 1 0 2 2 2 0 Glycoprotein encoding membrane proteins RL5A and RL6 Hydrolase_4 PF12146.8 RLN98323.1 - 0.092 12.0 0.1 0.36 10.0 0.1 1.8 1 1 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 RLN98323.1 - 0.11 12.1 0.2 0.77 9.4 0.0 2.3 2 1 1 3 3 3 0 PGAP1-like protein E2F_CC-MB PF16421.5 RLN98325.1 - 5.6e-24 84.3 0.0 9.8e-24 83.5 0.0 1.4 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain SDP_N PF12278.8 RLN98325.1 - 0.015 15.4 3.6 0.016 15.3 2.1 1.8 2 0 0 2 2 2 0 Sex determination protein N terminal UCMA PF17085.5 RLN98325.1 - 1.2 9.2 5.0 0.58 10.2 1.9 2.0 2 0 0 2 2 2 0 Unique cartilage matrix associated protein DUF2315 PF10231.9 RLN98326.1 - 0.026 14.6 1.6 0.03 14.4 1.6 1.1 1 0 0 1 1 1 0 Apoptogenic protein 1 Phage_1_1 PF08200.11 RLN98326.1 - 0.4 11.1 0.2 0.4 11.1 0.2 2.1 1 1 1 2 2 2 0 Bacteriophage 1.1 Protein HORMA PF02301.18 RLN98327.1 - 2.3e-11 43.7 0.1 9.9e-05 22.0 0.0 2.1 1 1 1 2 2 2 2 HORMA domain SKG6 PF08693.10 RLN98327.1 - 0.0052 16.2 0.2 0.0088 15.4 0.2 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SPC25 PF06703.11 RLN98328.1 - 1.1e-23 83.8 0.8 5.8e-23 81.4 0.8 1.8 1 1 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Proton_antipo_N PF00662.20 RLN98328.1 - 0.048 13.7 0.0 0.099 12.7 0.0 1.5 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Clc-like PF07062.12 RLN98328.1 - 0.082 12.4 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Clc-like LEM PF03020.15 RLN98329.1 - 0.24 11.0 1.0 5.2 6.7 0.0 2.5 2 0 0 2 2 2 0 LEM domain MutS_V PF00488.21 RLN98330.1 - 9.8e-10 38.8 0.0 1.4e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 MutS domain V Arm PF00514.23 RLN98334.1 - 1.2e-21 76.0 0.0 0.00027 20.9 0.0 4.3 4 0 0 4 4 4 4 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 RLN98334.1 - 0.00072 19.5 0.0 0.21 11.7 0.0 2.9 1 1 3 4 4 4 2 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 RLN98334.1 - 0.093 13.3 2.6 19 5.9 0.0 4.0 2 2 2 4 4 4 0 HEAT-like repeat Homeobox_KN PF05920.11 RLN98336.1 - 3.4e-17 62.0 0.2 3.4e-17 62.0 0.2 2.1 3 0 0 3 3 3 1 Homeobox KN domain Homeodomain PF00046.29 RLN98336.1 - 8.8e-10 38.3 0.6 1.9e-09 37.2 0.6 1.6 1 0 0 1 1 1 1 Homeodomain SLC35F PF06027.12 RLN98337.1 - 1.3e-48 166.1 21.0 8.8e-39 133.8 5.1 4.0 2 1 2 4 4 4 3 Solute carrier family 35 CRT-like PF08627.10 RLN98337.1 - 4.4e-09 35.7 2.2 5.2e-09 35.5 1.5 1.4 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 RLN98337.1 - 2.5e-07 30.2 12.5 6.9e-07 28.8 2.0 2.5 2 1 1 3 3 3 2 UAA transporter family Mg_trans_NIPA PF05653.14 RLN98337.1 - 7.5e-06 25.3 1.9 0.00043 19.5 1.1 2.4 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 RLN98337.1 - 5.8e-05 23.3 20.3 0.0056 16.9 7.3 3.0 3 0 0 3 3 3 2 EamA-like transporter family Meth_synt_1 PF08267.12 RLN98338.1 - 2.4e-89 299.9 0.0 4.3e-89 299.1 0.0 1.4 1 0 0 1 1 1 1 Cobalamin-independent synthase, N-terminal domain Meth_synt_2 PF01717.18 RLN98338.1 - 9.5e-70 235.4 0.0 1.3e-64 218.5 0.0 3.1 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain PCO_ADO PF07847.12 RLN98338.1 - 5.3e-25 88.1 0.0 9.3e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 PCO_ADO TBCC PF07986.12 RLN98338.1 - 1.4e-13 50.6 0.1 4.4e-13 49.0 0.1 1.9 1 1 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 RLN98338.1 - 0.038 13.6 0.3 0.42 10.2 0.3 2.2 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal Rota_NS53 PF00981.17 RLN98339.1 - 0.29 9.9 3.6 0.46 9.3 3.6 1.2 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) AAA PF00004.29 RLN98340.1 - 1.7e-90 300.3 0.0 8e-44 149.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RLN98340.1 - 1.6e-18 66.2 17.7 2.6e-10 40.0 4.9 3.3 4 0 0 4 4 2 2 AAA+ lid domain RuvB_N PF05496.12 RLN98340.1 - 4.4e-12 46.0 0.0 4.5e-06 26.5 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RLN98340.1 - 2.5e-11 43.7 0.1 5.8e-06 26.3 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RLN98340.1 - 3.5e-11 43.8 11.7 1.1e-06 29.2 0.2 5.7 3 2 2 5 5 5 2 AAA ATPase domain TIP49 PF06068.13 RLN98340.1 - 1.6e-09 37.4 0.0 0.00039 19.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_2 PF07724.14 RLN98340.1 - 2.3e-08 34.3 0.0 0.012 15.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 RLN98340.1 - 3.1e-08 33.9 0.0 0.00064 19.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RLN98340.1 - 4.2e-08 33.6 0.3 0.00066 20.0 0.0 4.4 3 2 1 4 4 3 1 AAA domain RNA_helicase PF00910.22 RLN98340.1 - 2.1e-06 28.1 0.0 0.015 15.7 0.0 2.4 2 0 0 2 2 2 2 RNA helicase Rad17 PF03215.15 RLN98340.1 - 3.1e-06 27.2 0.0 0.0041 17.1 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_25 PF13481.6 RLN98340.1 - 6.1e-06 25.9 3.5 0.21 11.1 0.1 4.0 2 2 2 4 4 4 1 AAA domain AAA_28 PF13521.6 RLN98340.1 - 9.2e-06 26.0 0.0 0.016 15.5 0.0 3.0 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 RLN98340.1 - 1.8e-05 24.2 0.2 0.029 13.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 RLN98340.1 - 1.8e-05 24.5 0.0 0.015 15.1 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 RLN98340.1 - 2.7e-05 24.2 0.0 0.063 13.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 RLN98340.1 - 2.7e-05 24.0 0.2 0.18 11.6 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RLN98340.1 - 5.1e-05 23.8 0.0 0.0059 17.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RLN98340.1 - 6.4e-05 22.5 0.0 0.026 14.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region TsaE PF02367.17 RLN98340.1 - 0.00089 19.3 0.0 0.096 12.7 0.0 2.6 2 1 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 RLN98340.1 - 0.0009 18.6 0.0 0.18 11.1 0.0 2.6 2 0 0 2 2 2 1 KaiC Sigma54_activ_2 PF14532.6 RLN98340.1 - 0.00098 19.3 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 RLN98340.1 - 0.0011 18.3 0.0 0.2 10.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.6 RLN98340.1 - 0.0012 18.6 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 RLN98340.1 - 0.0013 18.6 0.0 0.093 12.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 RLN98340.1 - 0.0019 18.1 0.3 1.1 9.1 0.0 4.0 4 0 0 4 4 4 1 NACHT domain Sigma54_activat PF00158.26 RLN98340.1 - 0.0038 17.0 0.0 0.3 10.8 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain DUF815 PF05673.13 RLN98340.1 - 0.0047 16.1 0.0 0.076 12.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 RLN98340.1 - 0.0079 16.7 0.0 0.67 10.5 0.0 2.8 2 1 0 2 2 2 1 ABC transporter AAA_17 PF13207.6 RLN98340.1 - 0.03 14.8 0.0 2.9 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 RLN98340.1 - 0.043 14.1 1.7 0.73 10.1 0.0 3.0 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Parvo_NS1 PF01057.17 RLN98340.1 - 0.047 12.8 0.0 0.23 10.5 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 SKI PF01202.22 RLN98340.1 - 0.059 13.5 0.0 3.4 7.8 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase PhoH PF02562.16 RLN98340.1 - 0.089 12.2 0.2 0.67 9.4 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 RLN98340.1 - 0.1 12.9 0.3 1.3 9.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain Cytidylate_kin2 PF13189.6 RLN98340.1 - 0.13 12.3 0.0 12 5.9 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase-like family DUF2075 PF09848.9 RLN98340.1 - 0.15 11.3 0.0 0.33 10.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 RLN98340.1 - 0.15 11.7 4.6 0.51 10.0 0.0 3.6 3 1 0 3 3 3 0 AAA domain AAA_11 PF13086.6 RLN98341.1 - 1e-64 218.8 2.6 3.8e-34 118.7 0.5 3.6 2 1 1 3 3 3 2 AAA domain AAA_12 PF13087.6 RLN98341.1 - 4.1e-10 39.6 0.1 7.7e-10 38.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RLN98341.1 - 5e-09 36.2 1.5 0.00014 21.6 0.4 2.8 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 RLN98341.1 - 2.3e-06 28.0 0.5 2.3e-06 28.0 0.5 2.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 RLN98341.1 - 0.071 13.1 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RLN98341.1 - 0.14 12.5 1.7 0.26 11.6 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.18 RLN98341.1 - 0.14 11.9 0.7 11 5.7 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Ran_BP1 PF00638.18 RLN98342.1 - 7.6e-37 126.3 1.0 1.2e-36 125.7 1.0 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 RLN98342.1 - 0.00017 21.5 0.8 0.00055 19.9 0.8 1.8 1 1 0 1 1 1 1 WH1 domain DUF5486 PF17588.2 RLN98342.1 - 0.035 14.0 0.3 0.077 12.9 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5486) PAP_assoc PF03828.19 RLN98346.1 - 6.3e-13 48.7 0.0 1.2e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 RLN98346.1 - 0.0057 16.9 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF2786 PF10979.8 RLN98346.1 - 0.64 10.0 2.9 0.43 10.5 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) DUF2441 PF10386.9 RLN98347.1 - 0.15 12.1 0.9 1.3 9.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2441) GP120 PF00516.18 RLN98347.1 - 4.8 5.6 7.3 8.4 4.9 7.3 1.3 1 0 0 1 1 1 0 Envelope glycoprotein GP120 PDZ_6 PF17820.1 RLN98348.1 - 2.7e-09 36.7 0.1 1.1e-08 34.8 0.1 2.1 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RLN98348.1 - 9.7e-07 29.1 0.0 2.5e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RLN98348.1 - 0.00064 20.0 0.0 0.0028 17.9 0.0 2.1 2 0 0 2 2 2 1 PDZ domain STI1 PF17830.1 RLN98348.1 - 0.84 9.6 26.0 1.6 8.7 24.9 2.1 1 1 1 2 2 2 0 STI1 domain XPC-binding PF09280.11 RLN98348.1 - 6.8 6.5 24.2 0.83 9.4 6.1 3.0 2 1 1 3 3 3 0 XPC-binding domain DNA_pol3_beta PF00712.19 RLN98349.1 - 0.086 13.0 0.2 0.24 11.5 0.2 1.7 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain VASt PF16016.5 RLN98350.1 - 1.3e-07 32.1 0.0 0.0016 18.8 0.0 3.1 2 1 0 2 2 2 2 VAD1 Analog of StAR-related lipid transfer domain PTAC PF06130.12 RLN98351.1 - 0.24 11.6 5.3 3.3 7.9 0.5 3.4 4 0 0 4 4 4 0 Phosphate propanoyltransferase Peptidase_M16_C PF05193.21 RLN98352.1 - 6e-17 62.2 0.0 1.7e-16 60.8 0.0 1.7 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 RLN98352.1 - 0.0046 17.0 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Rsm22 PF09243.10 RLN98353.1 - 2.5e-37 128.6 0.1 5.6e-37 127.5 0.1 1.6 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 RLN98353.1 - 1.9e-09 37.6 0.0 6.7e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN98353.1 - 9.5e-09 35.9 0.0 1.5e-05 25.7 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 RLN98353.1 - 5.9e-06 26.9 0.0 2.1e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN98353.1 - 0.0085 15.9 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 RLN98353.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_PK PF05891.12 RLN98353.1 - 0.037 13.5 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase RmlD_sub_bind PF04321.17 RLN98356.1 - 1.5e-13 50.5 0.0 6.4e-07 28.8 0.0 2.8 1 1 1 2 2 2 2 RmlD substrate binding domain Epimerase PF01370.21 RLN98356.1 - 9.2e-13 48.2 0.0 3.4e-07 30.0 0.0 2.4 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RLN98356.1 - 0.022 14.2 0.0 4.3 6.6 0.0 2.3 1 1 1 2 2 2 0 GDP-mannose 4,6 dehydratase IPK PF03770.16 RLN98357.1 - 1.6e-41 142.4 0.0 1.9e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase SapB_2 PF03489.17 RLN98358.1 - 1.8e-16 60.0 25.6 0.00014 21.9 0.3 7.9 7 1 1 8 8 8 5 Saposin-like type B, region 2 SapB_1 PF05184.15 RLN98358.1 - 0.007 16.4 24.8 0.21 11.6 1.4 6.1 6 0 0 6 6 6 3 Saposin-like type B, region 1 DUF1477 PF07346.11 RLN98358.1 - 0.016 15.4 1.0 14 6.0 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1477) MMS19_C PF12460.8 RLN98358.1 - 0.081 12.0 1.9 0.22 10.6 1.5 1.9 1 1 1 2 2 2 0 RNAPII transcription regulator C-terminal Duffy_binding PF05424.11 RLN98358.1 - 0.14 12.2 0.2 7.5 6.6 0.0 2.5 2 0 0 2 2 2 0 Duffy binding domain AA_permease_2 PF13520.6 RLN98360.1 - 1.2e-36 126.5 41.8 1.7e-36 126.0 41.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN98360.1 - 6.8e-28 97.5 41.8 8.9e-28 97.1 41.8 1.1 1 0 0 1 1 1 1 Amino acid permease Myb_DNA-binding PF00249.31 RLN98361.1 - 9.5e-29 99.3 9.0 6.3e-15 55.1 1.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN98361.1 - 1e-21 76.9 2.2 4.6e-12 46.0 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SWIM PF04434.17 RLN98361.1 - 6.4e-07 28.9 0.7 1.5e-06 27.7 0.7 1.6 1 0 0 1 1 1 1 SWIM zinc finger Myb_DNA-bind_7 PF15963.5 RLN98361.1 - 2.8e-06 27.1 1.3 0.0012 18.7 0.2 2.6 1 1 1 2 2 2 2 Myb DNA-binding like MULE PF10551.9 RLN98361.1 - 9.7e-05 22.7 0.0 0.00023 21.5 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain SLIDE PF09111.10 RLN98361.1 - 0.03 14.4 0.3 0.13 12.3 0.1 2.0 2 0 0 2 2 2 0 SLIDE SANT_DAMP1_like PF16282.5 RLN98361.1 - 0.27 11.5 1.1 9.3 6.5 0.2 2.5 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 AA_permease_2 PF13520.6 RLN98362.1 - 3.4e-36 125.0 47.7 4.9e-36 124.5 47.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN98362.1 - 5.3e-27 94.5 47.7 9.2e-26 90.5 48.2 1.9 1 1 1 2 2 2 2 Amino acid permease Pyridoxal_deC PF00282.19 RLN98363.1 - 1.7e-76 257.4 0.0 2.6e-76 256.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF2181 PF10223.9 RLN98364.1 - 6e-42 143.8 0.1 9.5e-42 143.1 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) JmjC PF02373.22 RLN98365.1 - 1.5e-39 135.0 0.6 3.9e-39 133.6 0.1 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.16 RLN98365.1 - 6.9e-12 45.6 7.5 6.9e-12 45.6 7.5 2.0 3 0 0 3 3 3 1 C5HC2 zinc finger JmjN PF02375.17 RLN98365.1 - 1.2e-10 41.1 0.1 3.7e-10 39.6 0.1 1.8 1 0 0 1 1 1 1 jmjN domain DUF1033 PF06279.11 RLN98365.1 - 0.13 12.5 0.7 0.28 11.4 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) Ank_4 PF13637.6 RLN98366.1 - 1.5e-46 156.2 5.4 7.7e-11 42.3 0.2 7.5 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN98366.1 - 4.3e-44 149.0 5.6 5.4e-14 52.6 0.7 5.4 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN98366.1 - 6.9e-36 121.9 10.9 2.9e-08 33.8 0.0 7.1 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 RLN98366.1 - 1.2e-31 107.7 16.3 0.00089 19.6 0.1 9.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 RLN98366.1 - 4e-25 85.1 9.1 0.043 14.4 0.1 8.6 8 0 0 8 8 8 6 Ankyrin repeat WW PF00397.26 RLN98366.1 - 2.9e-07 30.4 0.2 6.2e-07 29.4 0.2 1.6 1 0 0 1 1 1 1 WW domain TetR_C_6 PF13977.6 RLN98366.1 - 0.037 14.2 5.1 0.17 12.1 5.1 2.3 1 0 0 1 1 1 0 BetI-type transcriptional repressor, C-terminal ENTH PF01417.20 RLN98367.1 - 1.1e-11 44.9 0.2 5.8e-05 23.1 0.1 2.4 1 1 1 2 2 2 2 ENTH domain RAP1 PF07218.11 RLN98367.1 - 9.4 4.4 8.6 14 3.8 8.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4200 PF13863.6 RLN98368.1 - 1.3e-33 115.9 21.0 1.3e-33 115.9 21.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) BAR_3 PF16746.5 RLN98368.1 - 0.00011 22.1 8.8 0.00011 22.1 8.8 2.1 1 1 1 2 2 2 1 BAR domain of APPL family CCDC53 PF10152.9 RLN98368.1 - 1 9.8 8.2 0.18 12.2 2.6 2.3 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex XPG_N PF00752.17 RLN98369.1 - 7.5e-28 97.0 0.0 1.9e-27 95.7 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 RLN98369.1 - 3.8e-27 94.5 2.8 1.7e-25 89.2 0.0 3.6 3 0 0 3 3 3 1 XPG I-region XPG_I_2 PF12813.7 RLN98369.1 - 0.0024 17.4 4.7 0.049 13.1 4.6 2.7 1 1 0 1 1 1 1 XPG domain containing AMP-binding PF00501.28 RLN98370.1 - 2.6e-93 313.0 0.0 3.1e-93 312.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cas_Cas2CT1978 PF09707.10 RLN98370.1 - 0.065 13.3 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) AMP-binding PF00501.28 RLN98371.1 - 7.2e-92 308.2 0.0 8.8e-92 307.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PspA_IM30 PF04012.12 RLN98372.1 - 0.021 14.4 0.1 0.036 13.7 0.1 1.4 1 0 0 1 1 1 0 PspA/IM30 family MAD PF05557.13 RLN98372.1 - 0.033 12.6 0.3 0.037 12.4 0.3 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein JIP_LZII PF16471.5 RLN98372.1 - 0.045 13.9 1.3 0.051 13.7 0.3 1.6 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II E2R135 PF11570.8 RLN98372.1 - 0.068 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 zf-UBR PF02207.20 RLN98373.1 - 1.9e-17 63.2 15.9 1.9e-17 63.2 15.9 3.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) AP_endonuc_2 PF01261.24 RLN98374.1 - 5.2e-06 26.1 0.0 1.6e-05 24.4 0.0 1.7 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel KNOX2 PF03791.13 RLN98374.1 - 0.04 13.4 0.0 0.081 12.4 0.0 1.5 1 0 0 1 1 1 0 KNOX2 domain PH PF00169.29 RLN98375.1 - 3.3e-11 43.6 0.0 7.3e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RLN98375.1 - 0.01 16.2 2.4 0.021 15.2 0.0 2.8 3 1 0 3 3 3 0 Pleckstrin homology domain Caldesmon PF02029.15 RLN98375.1 - 0.78 8.4 45.3 1.2 7.8 45.3 1.2 1 0 0 1 1 1 0 Caldesmon zf-RanBP PF00641.18 RLN98376.1 - 6.8e-05 22.1 3.4 0.00012 21.3 3.4 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others WTX PF09422.10 RLN98376.1 - 0.004 16.3 5.1 0.0046 16.1 5.1 1.0 1 0 0 1 1 1 1 WTX protein GET2 PF08690.10 RLN98376.1 - 0.0061 16.3 2.2 0.0068 16.1 2.2 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 AP3D1 PF06375.11 RLN98376.1 - 0.018 15.2 5.3 0.025 14.8 5.3 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 zinc_ribbon_2 PF13240.6 RLN98376.1 - 0.02 14.6 1.8 0.043 13.6 1.8 1.5 1 0 0 1 1 1 0 zinc-ribbon domain LRR19-TM PF15176.6 RLN98376.1 - 0.063 13.3 0.2 0.092 12.8 0.2 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain FAM176 PF14851.6 RLN98376.1 - 0.099 12.3 1.4 0.12 12.0 1.4 1.2 1 0 0 1 1 1 0 FAM176 family DUF4551 PF15087.6 RLN98376.1 - 0.12 11.2 3.1 0.14 11.0 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF3597 PF12200.8 RLN98376.1 - 0.95 10.0 5.0 1.6 9.3 5.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Pro_isomerase PF00160.21 RLN98377.1 - 1.2e-39 136.1 0.2 2.9e-39 134.9 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4801 PF16059.5 RLN98377.1 - 0.079 12.9 0.6 0.19 11.7 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4801) Spore_II_R PF09551.10 RLN98377.1 - 4.4 7.8 12.0 2.1 8.8 1.0 3.1 2 1 0 3 3 3 0 Stage II sporulation protein R (spore_II_R) zf-Sec23_Sec24 PF04810.15 RLN98378.1 - 3.5e-17 62.2 6.8 6.2e-17 61.4 6.8 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 RLN98378.1 - 0.0089 15.4 0.1 0.02 14.3 0.1 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain TFIIA PF03153.13 RLN98378.1 - 8.9 6.2 28.2 12 5.8 28.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Arm PF00514.23 RLN98380.1 - 2.8e-18 65.3 1.0 0.00054 19.9 0.0 5.0 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RLN98380.1 - 6.3e-12 44.7 0.8 0.82 10.1 0.0 5.2 5 0 0 5 5 5 4 HEAT repeat HEAT_EZ PF13513.6 RLN98380.1 - 2.4e-07 31.1 9.8 0.0034 17.9 0.7 4.2 1 1 4 5 5 5 4 HEAT-like repeat HEAT_2 PF13646.6 RLN98380.1 - 4.3e-06 27.0 10.5 0.00055 20.3 1.8 3.3 1 1 3 4 4 4 3 HEAT repeats NFACT-R_2 PF18297.1 RLN98380.1 - 0.00083 19.5 2.1 29 4.9 0.0 4.5 1 1 4 5 5 5 0 NFACT protein RNA binding domain HEAT_PBS PF03130.16 RLN98380.1 - 0.0085 16.7 15.0 12 7.0 0.3 5.3 5 0 0 5 5 5 2 PBS lyase HEAT-like repeat PIN_2 PF10130.9 RLN98380.1 - 0.014 15.6 3.0 16 5.7 0.0 3.9 2 1 2 4 4 4 0 PIN domain DUF294_C PF10335.9 RLN98380.1 - 0.015 15.1 0.5 5.4 6.8 0.0 3.0 2 1 1 3 3 3 0 Putative nucleotidyltransferase substrate binding domain Tox-MPTase3 PF15639.6 RLN98380.1 - 0.016 15.1 0.1 0.49 10.3 0.0 3.0 1 1 1 2 2 2 0 Metallopeptidase toxin 3 DDE_Tnp_IS66_C PF13817.6 RLN98380.1 - 0.032 14.5 0.0 86 3.5 0.0 4.2 5 0 0 5 5 5 0 IS66 C-terminal element ATP-synt_F PF01990.17 RLN98380.1 - 0.16 12.3 0.2 5.2 7.5 0.0 2.8 1 1 3 4 4 4 0 ATP synthase (F/14-kDa) subunit baeRF_family10 PF18854.1 RLN98380.1 - 0.21 11.8 4.0 7.8 6.7 0.0 4.0 1 1 3 5 5 5 0 Bacterial archaeo-eukaryotic release factor family 10 CRA_rpt PF07046.11 RLN98380.1 - 0.28 11.4 7.5 52 4.1 0.1 4.1 4 0 0 4 4 4 0 Cytoplasmic repetitive antigen (CRA) like repeat AAA_25 PF13481.6 RLN98381.1 - 0.0022 17.6 0.1 0.0071 15.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.7 RLN98381.1 - 0.061 12.2 0.0 0.094 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Y_phosphatase PF00102.27 RLN98381.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Macoilin PF09726.9 RLN98382.1 - 0.0023 16.6 23.1 0.0035 16.0 23.1 1.1 1 0 0 1 1 1 1 Macoilin family DUF2968 PF11180.8 RLN98382.1 - 6.9 6.3 34.8 2.2 7.9 16.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF1765 PF08578.10 RLN98383.1 - 9.4e-13 48.7 1.3 1.5e-12 48.1 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Dimer_Tnp_hAT PF05699.14 RLN98384.1 - 0.00014 21.6 0.0 0.00037 20.2 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 RLN98384.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) EF-1_beta_acid PF10587.9 RLN98385.1 - 0.28 11.7 10.1 0.49 10.9 10.1 1.4 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Cofilin_ADF PF00241.20 RLN98386.1 - 5.4e-32 110.1 0.1 9.8e-32 109.3 0.1 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein C2 PF00168.30 RLN98386.1 - 7.1e-13 48.7 0.0 1.4e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain Arm PF00514.23 RLN98386.1 - 8e-10 38.4 48.0 0.0016 18.4 0.2 12.4 12 0 0 12 12 12 4 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 RLN98386.1 - 6.1e-07 29.6 0.5 0.51 10.4 0.0 4.7 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RLN98386.1 - 2.6e-05 24.5 1.7 2.6e-05 24.5 1.7 8.3 6 2 1 8 8 8 2 HEAT repeats KAP PF05804.12 RLN98386.1 - 0.00033 19.0 0.0 0.16 10.1 0.0 3.8 5 0 0 5 5 5 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 RLN98386.1 - 0.00055 19.3 2.5 0.47 9.7 0.0 4.0 5 0 0 5 5 5 2 V-ATPase subunit H HEAT PF02985.22 RLN98386.1 - 0.00089 19.3 50.8 0.0065 16.6 0.1 11.6 12 0 0 12 12 12 2 HEAT repeat Proteasom_PSMB PF10508.9 RLN98386.1 - 0.0058 15.2 0.0 5.5 5.4 0.0 3.7 4 0 0 4 4 4 1 Proteasome non-ATPase 26S subunit RICTOR_N PF14664.6 RLN98386.1 - 0.021 13.8 3.2 0.019 14.0 0.6 2.4 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term UNC45-central PF11701.8 RLN98386.1 - 0.83 9.6 11.9 17 5.3 0.0 5.4 6 0 0 6 6 6 0 Myosin-binding striated muscle assembly central HAT_KAT11 PF08214.11 RLN98387.1 - 3e-16 59.6 0.0 5e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein Bromodomain PF00439.25 RLN98387.1 - 3.2e-15 56.0 0.0 6.4e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain RGS PF00615.19 RLN98387.1 - 2e-09 37.7 0.0 9.7e-06 25.8 0.0 2.7 2 0 0 2 2 2 2 Regulator of G protein signaling domain ZZ PF00569.17 RLN98387.1 - 0.0045 16.8 4.3 0.0045 16.8 4.3 2.2 2 0 0 2 2 2 1 Zinc finger, ZZ type Polysacc_deac_1 PF01522.21 RLN98388.1 - 7.4e-16 58.2 0.0 4e-15 55.8 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 RLN98388.1 - 0.033 13.4 0.0 0.16 11.1 0.0 2.1 2 1 1 3 3 3 0 Divergent polysaccharide deacetylase MARVEL PF01284.23 RLN98389.1 - 2.2e-10 40.7 14.1 2.9e-10 40.3 14.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain MARVEL PF01284.23 RLN98390.1 - 0.0014 18.7 19.4 0.0084 16.2 19.4 1.9 1 1 0 1 1 1 1 Membrane-associating domain RseC_MucC PF04246.12 RLN98390.1 - 0.3 11.0 4.7 0.31 11.0 3.0 1.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Coa1 PF08695.10 RLN98391.1 - 0.0002 21.1 0.0 0.0032 17.2 0.0 2.7 2 1 0 2 2 2 1 Cytochrome oxidase complex assembly protein 1 MARVEL PF01284.23 RLN98391.1 - 0.00051 20.1 8.2 0.0011 19.0 8.2 1.6 1 0 0 1 1 1 1 Membrane-associating domain MARVEL PF01284.23 RLN98392.1 - 3.1e-09 37.0 17.4 4.1e-09 36.6 17.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain Competence PF03772.16 RLN98394.1 - 0.041 13.2 0.0 0.23 10.7 0.0 1.8 2 0 0 2 2 2 0 Competence protein adh_short PF00106.25 RLN98395.1 - 2.1e-49 167.6 2.0 2.8e-49 167.3 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RLN98395.1 - 2e-34 119.2 0.6 2.4e-34 118.9 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RLN98395.1 - 1.4e-10 41.3 0.5 2.2e-10 40.7 0.5 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 RLN98395.1 - 0.0002 21.3 0.1 0.00058 19.8 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 RLN98395.1 - 0.0003 20.4 0.4 0.066 12.7 0.4 2.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ank_2 PF12796.7 RLN98396.1 - 6.2e-39 132.5 6.7 2.4e-14 53.7 0.0 5.4 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RLN98396.1 - 4.4e-32 106.5 7.5 0.00012 22.2 0.1 9.6 10 0 0 10 10 10 5 Ankyrin repeat Ank_4 PF13637.6 RLN98396.1 - 6.8e-31 106.2 7.3 3.2e-10 40.3 0.0 6.4 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 RLN98396.1 - 4e-26 90.3 17.5 6e-07 29.6 1.4 7.7 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 RLN98396.1 - 5.9e-23 80.6 11.4 2.3e-07 31.0 0.1 7.2 6 2 2 8 8 8 4 Ankyrin repeats (many copies) Hom_end PF05204.14 RLN98397.1 - 0.034 14.3 2.8 3.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Homing endonuclease EMC1_C PF07774.13 RLN98398.1 - 2.2e-23 83.1 0.2 2.3e-23 83.0 0.2 1.0 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal Oxysterol_BP PF01237.18 RLN98399.1 - 4.1e-44 150.9 0.0 1e-33 116.7 0.0 2.2 1 1 1 2 2 2 2 Oxysterol-binding protein START PF01852.19 RLN98399.1 - 1.4e-14 54.1 0.1 1.1e-08 34.8 0.0 2.5 2 0 0 2 2 2 2 START domain PH PF00169.29 RLN98399.1 - 1.1e-12 48.3 0.0 2.3e-11 44.1 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 RLN98399.1 - 4.3e-05 23.9 0.1 0.00011 22.6 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 RLN98399.1 - 0.0058 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain SMYLE_N PF18615.1 RLN98399.1 - 0.12 11.9 1.6 0.2 11.2 1.6 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain HALZ PF02183.18 RLN98400.1 - 0.0044 17.2 2.2 0.0078 16.4 2.2 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_1 PF00170.21 RLN98400.1 - 0.0085 16.2 2.3 0.016 15.3 2.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor DivIC PF04977.15 RLN98400.1 - 0.019 14.7 2.3 0.029 14.1 2.3 1.3 1 0 0 1 1 1 0 Septum formation initiator FlaC_arch PF05377.11 RLN98400.1 - 0.036 14.5 0.6 0.13 12.7 0.1 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 RLN98400.1 - 0.053 14.0 8.0 0.082 13.4 8.0 1.3 1 0 0 1 1 1 0 Cell division protein ZapB DUF2570 PF10828.8 RLN98400.1 - 0.099 12.5 1.0 0.17 11.7 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Prefoldin_2 PF01920.20 RLN98401.1 - 5.8e-14 51.9 10.8 5.8e-14 51.9 10.8 1.9 2 0 0 2 2 2 1 Prefoldin subunit TPR_2 PF07719.17 RLN98401.1 - 0.00014 21.7 4.0 0.053 13.6 1.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 RLN98401.1 - 0.00014 21.5 1.4 0.37 10.7 0.5 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN98401.1 - 0.00021 21.3 3.9 0.0098 16.0 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN98401.1 - 0.00024 21.5 1.0 0.00024 21.5 1.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN98401.1 - 0.0047 16.9 0.2 0.02 14.9 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 RLN98401.1 - 0.0077 16.5 0.1 0.024 15.0 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat Osmo_CC PF08946.10 RLN98401.1 - 0.02 15.1 3.9 0.58 10.4 0.8 2.9 2 0 0 2 2 2 0 Osmosensory transporter coiled coil BCL9 PF11502.8 RLN98401.1 - 0.026 14.3 0.5 0.27 11.1 0.2 2.4 2 0 0 2 2 2 0 B-cell lymphoma 9 protein CHDCT2 PF08074.11 RLN98401.1 - 0.026 14.7 2.3 0.031 14.5 0.2 1.9 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain TPR_14 PF13428.6 RLN98401.1 - 0.13 13.2 3.7 1.9 9.5 0.7 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN98401.1 - 0.15 12.7 1.4 7.3 7.5 0.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat V_ATPase_I PF01496.19 RLN98401.1 - 0.2 9.5 2.7 0.24 9.3 2.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.12 RLN98401.1 - 0.27 9.7 4.0 0.3 9.6 4.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Nsp1_C PF05064.13 RLN98401.1 - 0.4 10.5 7.3 1.6 8.5 0.2 2.4 2 0 0 2 2 2 0 Nsp1-like C-terminal region Jnk-SapK_ap_N PF09744.9 RLN98401.1 - 0.4 10.9 15.1 0.95 9.7 1.5 2.7 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Occludin_ELL PF07303.13 RLN98401.1 - 0.75 10.6 6.5 4.1 8.2 0.4 3.1 1 1 1 2 2 2 0 Occludin homology domain LMBR1 PF04791.16 RLN98401.1 - 0.96 8.3 2.6 1.2 8.0 2.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CCDC-167 PF15188.6 RLN98401.1 - 1 9.8 7.0 2.8 8.3 6.0 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Med9 PF07544.13 RLN98401.1 - 1.6 8.8 8.1 0.26 11.4 0.2 2.9 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 AAA_13 PF13166.6 RLN98401.1 - 1.9 7.0 12.0 0.15 10.7 1.7 2.2 1 1 1 2 2 2 0 AAA domain TRAF_BIRC3_bd PF16673.5 RLN98401.1 - 2.2 8.1 6.9 0.34 10.7 0.3 2.8 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Fib_alpha PF08702.10 RLN98401.1 - 2.8 8.1 7.4 1.4 9.1 5.1 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family YabA PF06156.13 RLN98401.1 - 2.8 8.6 6.7 35 5.1 5.3 2.7 2 1 0 2 2 2 0 Initiation control protein YabA Spc7 PF08317.11 RLN98401.1 - 7.9 5.3 17.6 6 5.7 3.9 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein TPR_10 PF13374.6 RLN98401.1 - 8.9 6.3 9.1 4.2 7.4 0.7 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat Ank_4 PF13637.6 RLN98402.1 - 6e-13 49.0 0.1 4.6e-07 30.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RLN98402.1 - 4.1e-11 42.8 0.3 6.9e-05 23.1 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 RLN98402.1 - 1.1e-10 42.0 0.0 1.8e-10 41.2 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RLN98402.1 - 1.1e-06 28.7 0.2 0.0057 16.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN98402.1 - 4.2e-06 26.7 0.0 0.023 15.2 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Pkinase_Tyr PF07714.17 RLN98403.1 - 5.5e-43 147.1 0.0 6.6e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN98403.1 - 2.9e-42 144.8 0.0 4e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Sporozoite_P67 PF05642.11 RLN98405.1 - 0.6 8.1 1.8 0.66 8.0 1.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ank_2 PF12796.7 RLN98406.1 - 2.9e-81 268.1 20.7 1.9e-15 57.2 0.0 6.8 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN98406.1 - 8.2e-62 204.8 12.5 7.9e-11 42.3 0.0 10.6 4 2 8 12 12 12 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN98406.1 - 2.9e-55 183.6 21.2 1.3e-08 34.9 0.6 8.5 4 2 4 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 RLN98406.1 - 1.9e-52 173.5 22.3 5.2e-06 26.7 0.2 13.2 13 0 0 13 13 13 10 Ankyrin repeat Ank_3 PF13606.6 RLN98406.1 - 2.3e-48 156.6 11.9 0.00044 20.5 0.1 13.4 14 0 0 14 14 14 9 Ankyrin repeat Pkinase_Tyr PF07714.17 RLN98406.1 - 1.2e-40 139.5 0.0 1.9e-40 138.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN98406.1 - 2.6e-37 128.6 0.0 4.2e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PAP2_C PF14360.6 RLN98410.1 - 1.3e-19 70.5 3.2 1.3e-19 70.5 3.2 3.0 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 RLN98410.1 - 2.8e-06 27.1 2.1 2.8e-06 27.1 2.1 2.2 2 1 0 2 2 2 1 PAP2 superfamily YtpI PF14007.6 RLN98410.1 - 0.066 13.4 0.4 0.066 13.4 0.4 2.4 3 0 0 3 3 3 0 YtpI-like protein Cation_efflux PF01545.21 RLN98410.1 - 7.8 6.2 11.5 0.45 10.2 2.8 2.4 3 0 0 3 3 3 0 Cation efflux family BAT2_N PF07001.11 RLN98411.1 - 9.3e-13 49.1 2.5 1.4e-12 48.5 2.5 1.2 1 0 0 1 1 1 1 BAT2 N-terminus Ank_2 PF12796.7 RLN98412.1 - 1e-78 259.9 13.4 4.2e-13 49.7 0.2 6.0 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN98412.1 - 8.2e-77 252.7 9.2 3.8e-09 36.9 0.1 8.6 2 2 8 10 10 10 10 Ankyrin repeats (many copies) Ank PF00023.30 RLN98412.1 - 1.4e-55 183.4 15.8 1e-05 25.7 0.0 11.3 11 0 0 11 11 11 11 Ankyrin repeat Ank_3 PF13606.6 RLN98412.1 - 1.8e-55 178.3 3.6 0.0014 18.9 0.0 12.1 12 0 0 12 12 12 12 Ankyrin repeat Ank_5 PF13857.6 RLN98412.1 - 1.3e-51 171.9 16.3 9.7e-07 29.0 0.1 10.2 2 2 9 11 11 11 10 Ankyrin repeats (many copies) DUF1949 PF09186.11 RLN98412.1 - 0.00039 20.2 0.5 1.5 8.8 0.0 5.2 5 1 0 5 5 5 1 Domain of unknown function (DUF1949) PK_C PF02887.16 RLN98412.1 - 0.0012 19.0 4.9 35 4.7 0.0 5.0 5 1 0 6 6 6 0 Pyruvate kinase, alpha/beta domain Atu4866 PF11512.8 RLN98412.1 - 0.0029 17.9 0.2 55 4.2 0.0 4.0 4 0 0 4 4 4 0 Agrobacterium tumefaciens protein Atu4866 ArsP_1 PF03773.13 RLN98412.1 - 0.0048 16.1 3.2 6.8 5.7 0.0 3.8 4 0 0 4 4 4 1 Predicted permease Helitron_like_N PF14214.6 RLN98413.1 - 4.8e-11 43.2 0.0 4.8e-11 43.2 0.0 2.8 2 1 1 3 3 3 1 Helitron helicase-like domain at N-terminus SGL PF08450.12 RLN98416.1 - 1.8e-09 37.6 0.0 2.6e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 RLN98416.1 - 1.1e-05 25.2 0.4 0.28 11.3 0.0 4.0 3 0 0 3 3 3 3 NHL repeat Str_synth PF03088.16 RLN98416.1 - 0.0011 19.1 0.0 0.24 11.6 0.0 3.1 3 0 0 3 3 3 1 Strictosidine synthase Arylesterase PF01731.20 RLN98416.1 - 0.012 15.7 0.0 0.55 10.5 0.0 3.1 4 0 0 4 4 4 0 Arylesterase ABC1 PF03109.16 RLN98417.1 - 4.3e-26 91.4 0.1 1.2e-25 90.0 0.1 1.7 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 RLN98417.1 - 0.069 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.23 RLN98417.1 - 4.2 7.2 9.3 17 5.2 6.9 3.0 2 2 1 3 3 3 0 Phosphotransferase enzyme family Methyltransf_23 PF13489.6 RLN98418.1 - 1.3e-08 34.9 0.0 1.8e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RLN98418.1 - 0.0081 16.9 0.0 0.017 15.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN98418.1 - 0.0093 16.6 0.0 0.027 15.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RLN98418.1 - 0.15 12.7 0.1 0.42 11.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain SUIM_assoc PF16619.5 RLN98419.1 - 0.035 14.2 1.2 8.3 6.6 0.8 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 IU_nuc_hydro PF01156.19 RLN98420.1 - 3.9e-58 197.4 0.8 4.9e-57 193.8 0.8 1.9 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase CbiJ PF02571.14 RLN98420.1 - 0.076 12.5 0.2 0.13 11.7 0.2 1.3 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK DUF2004 PF09406.10 RLN98420.1 - 0.13 12.6 0.0 0.56 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2004) DUF2809 PF10990.8 RLN98421.1 - 0.014 16.1 0.3 0.014 16.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2809) Exo70 PF03081.15 RLN98422.1 - 3.4e-24 85.6 0.0 5.7e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit PAH PF02671.21 RLN98422.1 - 0.014 15.5 0.6 1 9.5 0.1 2.7 2 0 0 2 2 2 0 Paired amphipathic helix repeat Mito_carr PF00153.27 RLN98424.1 - 1.3e-65 217.4 2.9 8.7e-21 73.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 RLN98424.1 - 0.044 13.9 1.6 3.3 7.9 0.0 3.2 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif Mito_carr PF00153.27 RLN98425.1 - 6.2e-66 218.4 0.7 4.1e-21 74.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 RLN98425.1 - 0.018 14.2 1.1 0.21 10.7 0.5 2.7 2 1 1 3 3 3 0 Gammaproteobacterial serine protease HMG_box PF00505.19 RLN98426.1 - 9.5e-18 64.4 0.0 1.3e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RLN98426.1 - 4.4e-11 43.2 0.0 6.9e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 HMG-box domain IHABP4_N PF16174.5 RLN98426.1 - 0.061 13.9 0.1 0.11 13.2 0.1 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal IQ PF00612.27 RLN98427.1 - 0.098 12.5 0.9 0.27 11.1 0.9 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif FGGY_N PF00370.21 RLN98428.1 - 7.8e-73 245.0 0.0 1.3e-72 244.3 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 RLN98428.1 - 3.2e-64 216.3 0.8 4.9e-64 215.7 0.8 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain NMD3 PF04981.13 RLN98429.1 - 5.7e-40 137.3 0.2 7.6e-40 136.9 0.2 1.2 1 0 0 1 1 1 1 NMD3 family Peptidase_S28 PF05577.12 RLN98430.1 - 9.2e-11 41.2 0.3 1.2e-10 40.8 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 RskA PF10099.9 RLN98430.1 - 0.047 14.0 0.0 0.052 13.9 0.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Guanylate_kin PF00625.21 RLN98432.1 - 6.4e-55 185.7 0.3 1e-54 185.0 0.0 1.4 2 0 0 2 2 2 1 Guanylate kinase RIIa PF02197.17 RLN98432.1 - 2.2e-05 24.0 0.0 5.1e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit MMR_HSR1 PF01926.23 RLN98432.1 - 0.00018 21.6 0.0 0.00061 19.8 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RLN98432.1 - 0.00019 21.4 0.0 0.00048 20.1 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 RLN98432.1 - 0.00088 19.8 1.0 0.0038 17.8 0.7 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RLN98432.1 - 0.0066 16.8 0.0 0.018 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 RLN98432.1 - 0.0078 16.4 0.1 0.23 11.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 RLN98432.1 - 0.011 16.2 0.1 0.053 14.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Thymidylate_kin PF02223.17 RLN98432.1 - 0.045 13.4 0.1 0.32 10.6 0.0 2.3 2 1 1 3 3 3 0 Thymidylate kinase NTPase_1 PF03266.15 RLN98432.1 - 0.051 13.5 0.1 0.096 12.6 0.1 1.5 1 1 0 1 1 1 0 NTPase AAA_22 PF13401.6 RLN98432.1 - 0.073 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 RLN98432.1 - 0.096 12.6 0.1 0.17 11.7 0.1 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea GGGtGRT PF14057.6 RLN98432.1 - 0.12 11.4 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 GGGtGRT protein cNMP_binding PF00027.29 RLN98433.1 - 3.4e-05 23.8 0.0 0.00038 20.5 0.0 2.4 2 1 0 2 2 2 1 Cyclic nucleotide-binding domain ABC2_membrane_3 PF12698.7 RLN98434.1 - 2.8e-17 62.9 33.8 2e-16 60.1 33.8 2.2 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 RLN98434.1 - 5.2e-08 33.5 0.4 9.5e-08 32.6 0.4 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 RLN98434.1 - 0.0001 21.8 30.8 0.0031 16.9 25.4 2.7 2 1 0 2 2 2 2 ABC-2 type transporter AAA_23 PF13476.6 RLN98434.1 - 0.0014 19.2 0.3 0.0029 18.1 0.3 1.4 1 0 0 1 1 1 1 AAA domain ABC2_membrane_5 PF13346.6 RLN98434.1 - 0.0078 15.8 21.6 0.018 14.6 21.6 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 RLN98434.1 - 0.0083 16.0 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN98434.1 - 0.012 15.4 0.3 0.026 14.3 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 RLN98434.1 - 0.072 12.8 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 RLN98434.1 - 0.2 11.4 0.3 0.34 10.7 0.3 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Pkinase PF00069.25 RLN98435.1 - 6.4e-39 133.9 2.5 2.8e-19 69.5 2.1 2.7 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN98435.1 - 3.3e-20 72.5 0.7 2e-10 40.4 0.3 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase PglD_N PF17836.1 RLN98435.1 - 0.011 16.3 0.0 0.022 15.4 0.0 1.5 1 0 0 1 1 1 0 PglD N-terminal domain Pkinase_C PF00433.24 RLN98435.1 - 0.013 16.2 0.2 0.032 14.9 0.2 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain UPF0564 PF10595.9 RLN98436.1 - 6.8e-10 38.5 44.5 8.3e-10 38.3 43.6 1.6 1 1 0 1 1 1 1 Uncharacterised protein family UPF0564 AAA_13 PF13166.6 RLN98437.1 - 0.29 9.7 5.8 0.48 9.0 5.8 1.3 1 0 0 1 1 1 0 AAA domain PIN_4 PF13638.6 RLN98437.1 - 0.57 10.5 3.4 0.9 9.8 3.4 1.4 1 0 0 1 1 1 0 PIN domain DUF4337 PF14235.6 RLN98437.1 - 6.6 6.8 6.9 9 6.4 4.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Cys_Met_Meta_PP PF01053.20 RLN98438.1 - 1.4e-32 112.7 0.0 1.9e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 RLN98438.1 - 1.2e-06 28.0 0.0 1.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 RLN98438.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Phage_integrase PF00589.22 RLN98438.1 - 0.21 11.4 0.4 0.46 10.2 0.4 1.5 1 0 0 1 1 1 0 Phage integrase family Mito_carr PF00153.27 RLN98439.1 - 1.1e-22 79.7 0.0 1.3e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein Arm PF00514.23 RLN98440.1 - 8e-19 67.0 54.8 4.9e-06 26.4 0.3 14.8 16 0 0 16 16 16 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RLN98440.1 - 4.2e-07 30.3 4.3 0.0045 17.3 0.1 4.3 4 0 0 4 4 4 2 HEAT repeats DUF383 PF04063.14 RLN98440.1 - 0.00023 20.9 1.3 4.1 7.0 0.1 4.4 2 2 0 3 3 3 2 Domain of unknown function (DUF383) HEAT_EZ PF13513.6 RLN98440.1 - 0.00072 20.0 7.3 1.2 9.7 0.8 5.6 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.22 RLN98440.1 - 0.0041 17.2 8.8 0.36 11.2 0.1 6.2 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 RLN98440.1 - 0.0058 16.7 6.6 0.077 13.0 0.6 4.4 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm_2 PF04826.13 RLN98440.1 - 0.4 10.1 11.7 0.9 8.9 1.1 4.3 3 1 1 4 4 4 0 Armadillo-like RTTN_N PF14726.6 RLN98440.1 - 0.57 11.0 2.2 2.5e+02 2.6 0.0 4.9 3 2 1 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning KAP PF05804.12 RLN98440.1 - 0.77 7.8 12.5 0.079 11.1 0.1 3.7 3 1 0 4 4 4 0 Kinesin-associated protein (KAP) Myb_DNA-binding PF00249.31 RLN98441.1 - 3.1e-15 56.1 0.0 5.8e-06 26.4 0.0 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain OrfB_Zn_ribbon PF07282.11 RLN98441.1 - 9.5e-05 22.3 3.9 0.004 17.1 0.1 2.4 2 0 0 2 2 2 2 Putative transposase DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN98441.1 - 0.00067 19.9 0.0 0.5 10.6 0.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain MDMPI_N PF11716.8 RLN98441.1 - 0.085 13.5 0.3 0.085 13.5 0.3 2.7 2 1 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain GMC_oxred_N PF00732.19 RLN98442.1 - 1.1e-40 139.8 0.0 1.2e-40 139.7 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 RLN98442.1 - 0.061 12.4 0.0 0.061 12.4 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 RLN98442.1 - 0.069 12.5 0.0 0.081 12.3 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Mo-co_dimer PF03404.16 RLN98442.1 - 0.23 11.5 1.1 2 8.4 0.3 2.1 2 0 0 2 2 2 0 Mo-co oxidoreductase dimerisation domain ERM PF00769.19 RLN98443.1 - 5.6 6.7 24.5 13 5.5 1.4 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family SAM_2 PF07647.17 RLN98444.1 - 1.3e-10 41.3 0.0 2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RLN98444.1 - 1.3e-10 41.5 0.0 2.4e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 RLN98444.1 - 0.028 14.4 0.0 0.075 13.0 0.0 1.8 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain TAF4 PF05236.14 RLN98444.1 - 3.2 7.4 14.6 5.9 6.5 14.6 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Pkinase PF00069.25 RLN98445.1 - 2.7e-37 128.6 0.0 1.3e-30 106.7 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN98445.1 - 1.4e-24 86.8 0.0 1.1e-15 57.7 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 RLN98445.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 RLN98445.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RLN98445.1 - 0.11 11.2 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 RLN98447.1 - 3.6e-48 164.2 0.0 5e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN98447.1 - 3.7e-44 150.9 0.0 4.9e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 RLN98447.1 - 3.4e-07 29.9 4.8 0.00056 19.6 0.3 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RLN98447.1 - 3.1e-06 27.4 7.8 0.00026 21.3 1.3 3.2 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN98447.1 - 0.00013 22.1 0.7 12 6.9 0.0 4.1 4 0 0 4 4 4 1 Leucine Rich Repeat APH PF01636.23 RLN98447.1 - 0.017 15.0 0.0 0.2 11.5 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family CD34_antigen PF06365.12 RLN98447.1 - 0.023 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family LRR_6 PF13516.6 RLN98447.1 - 0.066 13.3 4.6 1.1 9.4 0.3 3.4 3 0 0 3 3 3 0 Leucine Rich repeat TMEM154 PF15102.6 RLN98447.1 - 0.096 12.6 0.6 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 TMEM154 protein family EphA2_TM PF14575.6 RLN98447.1 - 0.12 13.3 0.0 0.24 12.3 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.25 RLN98448.1 - 1.4e-51 175.4 0.0 2e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN98448.1 - 2.7e-44 151.4 0.0 3.7e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 RLN98448.1 - 3.7e-10 39.4 2.0 2.8e-06 27.0 0.3 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RLN98448.1 - 1.9e-09 37.6 1.0 1.1e-05 25.7 0.3 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RLN98448.1 - 0.0019 18.4 0.6 2.9 8.8 0.0 4.2 3 1 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 RLN98448.1 - 0.0052 16.7 3.6 2.1 8.6 0.0 3.9 4 0 0 4 4 3 1 Leucine Rich repeat SKG6 PF08693.10 RLN98448.1 - 0.0066 15.8 0.9 0.014 14.8 0.9 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.20 RLN98448.1 - 0.015 15.2 0.1 0.03 14.2 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.15 RLN98448.1 - 0.051 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Stevor PF17410.2 RLN98448.1 - 0.059 12.9 0.2 7.3 6.0 0.0 2.3 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame FTR1 PF03239.14 RLN98448.1 - 0.09 11.9 0.3 0.14 11.3 0.3 1.2 1 0 0 1 1 1 0 Iron permease FTR1 family APH PF01636.23 RLN98448.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 RLN98449.1 - 3.4e-48 164.3 0.0 4.9e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN98449.1 - 2.3e-43 148.4 0.0 3.1e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 RLN98449.1 - 8.8e-12 45.0 9.7 7e-07 29.5 0.6 3.8 2 2 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN98449.1 - 5.2e-09 35.7 11.2 2.7e-06 27.0 1.0 3.1 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 RLN98449.1 - 0.0018 18.6 5.6 8.3 7.4 0.0 5.0 4 1 0 4 4 4 1 Leucine Rich Repeat SKG6 PF08693.10 RLN98449.1 - 0.01 15.2 3.1 0.021 14.2 3.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LRR_6 PF13516.6 RLN98449.1 - 0.012 15.6 10.9 2.2 8.6 0.1 4.4 4 0 0 4 4 4 0 Leucine Rich repeat Syndecan PF01034.20 RLN98449.1 - 0.034 14.1 0.4 0.069 13.1 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain APH PF01636.23 RLN98449.1 - 0.062 13.2 0.3 1.3 8.9 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Adeno_E3_CR2 PF02439.15 RLN98449.1 - 0.079 12.7 2.1 0.15 11.8 2.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DAGAT PF03982.13 RLN98451.1 - 1.5e-31 109.4 0.0 2.5e-30 105.4 0.0 2.5 2 1 0 2 2 2 1 Diacylglycerol acyltransferase Glyco_hydro_72 PF03198.14 RLN98451.1 - 2.9e-14 53.0 0.0 3.8e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_72 PF03198.14 RLN98452.1 - 1.2e-15 57.6 0.0 1.2e-15 57.5 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase MDD_C PF18376.1 RLN98453.1 - 2.8e-71 239.1 0.0 4e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 RLN98453.1 - 2.1e-07 31.1 0.8 2.1e-07 31.1 0.8 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain WD40 PF00400.32 RLN98454.1 - 2.5e-24 85.0 6.7 5.2e-08 33.4 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN98454.1 - 6.9e-08 32.7 0.0 0.0011 19.2 0.0 4.3 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RLN98454.1 - 0.0028 16.7 0.5 3.9 6.3 0.0 3.2 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 RLN98454.1 - 0.056 13.5 0.0 1.1 9.3 0.0 2.7 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF1018 PF06252.12 RLN98454.1 - 0.12 13.3 0.0 0.2 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) DnaJ PF00226.31 RLN98456.1 - 1e-10 41.5 0.0 4.2e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain EF-hand_6 PF13405.6 RLN98456.1 - 3.7e-05 23.3 0.6 0.082 12.9 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RLN98456.1 - 0.0053 17.2 0.1 0.013 15.9 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RLN98456.1 - 0.012 15.1 0.3 6.7 6.5 0.0 2.5 2 0 0 2 2 2 0 EF hand RIIa PF02197.17 RLN98456.1 - 0.017 14.8 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit CRR7 PF12095.8 RLN98456.1 - 5.3 7.6 5.9 43 4.6 0.2 3.5 4 0 0 4 4 4 0 Protein CHLORORESPIRATORY REDUCTION 7 ABC_tran PF00005.27 RLN98457.1 - 1.9e-38 132.1 0.6 1e-19 71.4 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 RLN98457.1 - 1.9e-24 85.5 7.8 1.6e-22 79.3 6.7 2.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 RLN98457.1 - 8.2e-16 58.7 3.5 0.00015 21.7 0.0 4.0 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RLN98457.1 - 1.3e-06 28.0 7.4 0.011 15.2 0.0 3.5 4 0 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 RLN98457.1 - 0.0005 20.4 1.5 0.049 13.9 0.0 3.2 3 1 0 3 3 2 1 AAA domain DUF3584 PF12128.8 RLN98457.1 - 0.0023 15.5 0.1 0.0023 15.5 0.1 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3584) AAA_29 PF13555.6 RLN98457.1 - 0.0024 17.6 1.3 0.056 13.2 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 RLN98457.1 - 0.0044 17.1 0.0 0.19 11.8 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 RLN98457.1 - 0.005 17.4 0.4 3.4 8.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain FmiP_Thoc5 PF09766.9 RLN98457.1 - 0.0052 16.1 5.9 0.035 13.4 0.9 2.1 2 0 0 2 2 2 1 Fms-interacting protein/Thoc5 AAA_22 PF13401.6 RLN98457.1 - 0.0068 16.7 0.7 0.031 14.5 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_13 PF13166.6 RLN98457.1 - 0.0085 14.8 5.0 1.6 7.3 0.0 3.6 4 0 0 4 4 4 1 AAA domain SbcCD_C PF13558.6 RLN98457.1 - 0.013 15.8 0.4 1.8 8.8 0.1 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 RLN98457.1 - 0.022 15.1 0.1 0.47 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.15 RLN98457.1 - 0.04 13.8 0.1 0.095 12.6 0.1 1.7 1 0 0 1 1 1 0 NTPase RsgA_GTPase PF03193.16 RLN98457.1 - 0.045 13.7 0.4 0.85 9.5 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase NPV_P10 PF05531.12 RLN98457.1 - 0.05 14.1 1.5 0.16 12.4 1.5 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein AAA_15 PF13175.6 RLN98457.1 - 0.059 13.1 0.1 0.059 13.1 0.1 3.7 4 1 0 5 5 5 0 AAA ATPase domain AAA_33 PF13671.6 RLN98457.1 - 0.069 13.3 1.9 2.3 8.4 0.1 3.4 3 1 0 3 3 3 0 AAA domain AAA_25 PF13481.6 RLN98457.1 - 0.078 12.5 0.9 0.77 9.3 0.1 2.7 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 RLN98457.1 - 0.095 12.7 0.2 3.6 7.6 0.0 3.4 4 2 0 4 4 4 0 AAA domain NACHT PF05729.12 RLN98457.1 - 0.1 12.5 1.0 0.32 10.9 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 RLN98457.1 - 0.13 12.7 2.7 0.24 11.8 0.1 2.8 2 2 1 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 RLN98457.1 - 0.28 11.7 13.5 0.066 13.7 0.4 4.2 4 1 0 4 4 4 0 AAA domain AAA_30 PF13604.6 RLN98457.1 - 0.44 10.2 5.3 0.56 9.9 0.7 3.2 3 1 0 3 3 3 0 AAA domain RecG_N PF17190.4 RLN98457.1 - 0.57 11.0 6.8 2.9 8.7 0.2 3.1 2 1 0 2 2 2 0 RecG N-terminal helical domain DUF16 PF01519.16 RLN98457.1 - 1.1 9.8 7.8 1.6 9.2 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF4200 PF13863.6 RLN98457.1 - 1.4 9.3 11.1 0.38 11.2 3.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF87 PF01935.17 RLN98457.1 - 1.9 8.5 9.5 3.1 7.8 0.0 4.0 4 0 0 4 4 4 0 Helicase HerA, central domain Histone_HNS PF00816.21 RLN98457.1 - 2.1 9.2 6.0 0.8 10.6 1.2 2.4 2 0 0 2 2 2 0 H-NS histone family Dynamin_N PF00350.23 RLN98457.1 - 2.1 8.4 8.8 21 5.1 0.0 4.0 3 1 0 3 3 3 0 Dynamin family GrpE PF01025.19 RLN98457.1 - 3.3 7.4 13.9 0.1 12.3 2.7 2.9 3 0 0 3 3 3 0 GrpE Mesd PF10185.9 RLN98458.1 - 0.00085 19.3 0.1 0.0017 18.3 0.1 1.5 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor TIP120 PF08623.10 RLN98459.1 - 1.2e-47 161.8 1.5 1.8e-45 154.7 0.1 3.8 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 RLN98459.1 - 1.4e-15 56.0 12.0 0.026 14.8 0.0 11.4 12 0 0 12 12 11 4 HEAT repeat HEAT_2 PF13646.6 RLN98459.1 - 3.4e-15 56.2 6.1 0.011 16.1 0.0 7.8 5 3 4 9 9 9 4 HEAT repeats HEAT_EZ PF13513.6 RLN98459.1 - 1.1e-12 48.1 0.2 0.014 15.9 0.0 8.4 7 0 0 7 7 7 2 HEAT-like repeat CLASP_N PF12348.8 RLN98459.1 - 1.8e-07 30.9 0.4 0.18 11.3 0.0 5.4 4 1 2 6 6 6 3 CLASP N terminal Adaptin_N PF01602.20 RLN98459.1 - 3.3e-06 25.9 11.0 0.026 13.1 2.3 5.5 4 1 2 6 6 6 3 Adaptin N terminal region Cnd1 PF12717.7 RLN98459.1 - 2.6e-05 24.3 8.3 0.014 15.5 0.0 6.0 4 3 2 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Sec7_N PF12783.7 RLN98459.1 - 0.00038 20.4 0.1 0.11 12.3 0.0 4.6 4 1 2 6 6 6 1 Guanine nucleotide exchange factor in Golgi transport N-terminal RTP1_C1 PF10363.9 RLN98459.1 - 0.0031 17.7 9.1 0.38 10.9 0.0 6.2 7 1 0 7 7 7 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 PF11865.8 RLN98459.1 - 0.011 15.6 0.6 10 6.0 0.1 4.1 3 2 1 4 4 4 0 Domain of unknown function (DUF3385) HEAT_UF PF18817.1 RLN98459.1 - 0.014 15.6 0.3 0.22 11.8 0.1 2.9 3 0 0 3 3 3 0 Repeat of uncharacterized protein PH0542 Ipi1_N PF12333.8 RLN98459.1 - 0.018 15.7 0.6 16 6.2 0.0 4.5 5 0 0 5 5 3 0 Rix1 complex component involved in 60S ribosome maturation Arm PF00514.23 RLN98459.1 - 0.033 14.2 0.9 98 3.2 0.0 5.4 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF4042 PF13251.6 RLN98459.1 - 2.8 7.6 5.7 37 4.0 0.0 4.9 6 1 0 6 6 6 0 Domain of unknown function (DUF4042) Metallophos PF00149.28 RLN98460.1 - 8.3e-20 72.2 0.1 1.3e-19 71.5 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Smr PF01713.21 RLN98462.1 - 0.13 12.6 0.1 0.28 11.6 0.1 1.4 1 0 0 1 1 1 0 Smr domain DUF3123 PF11321.8 RLN98462.1 - 1.2 9.9 0.1 1.2 9.9 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3123) ALMS_repeat PF18727.1 RLN98462.1 - 2.2 8.2 8.0 0.18 11.7 1.4 2.4 2 0 0 2 2 2 0 Alstrom syndrome repeat DUF4724 PF15852.5 RLN98462.1 - 2.4 8.7 4.7 0.44 11.1 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4724) DHHC PF01529.20 RLN98463.1 - 9.3e-24 84.0 3.2 9.3e-24 84.0 3.2 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase EMP70 PF02990.16 RLN98463.1 - 1.1 7.9 3.6 0.44 9.2 0.6 1.7 2 0 0 2 2 2 0 Endomembrane protein 70 DZR PF12773.7 RLN98463.1 - 1.5 8.9 13.4 1 9.4 5.6 2.4 2 0 0 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 RLN98463.1 - 1.8 8.5 11.5 0.13 12.2 4.4 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 RLN98463.1 - 6.1 6.4 10.1 3.3 7.3 5.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain TGT PF01702.18 RLN98464.1 - 1.1e-71 241.9 0.0 1.3e-71 241.6 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase 5_3_exonuc_N PF02739.16 RLN98465.1 - 5e-34 117.5 0.0 7.3e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 RLN98465.1 - 3.7e-14 53.1 0.0 6.4e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold NYN_YacP PF05991.11 RLN98465.1 - 0.0061 16.5 0.0 4.4 7.2 0.0 2.2 2 0 0 2 2 2 2 YacP-like NYN domain Homeodomain PF00046.29 RLN98466.1 - 1.1e-29 102.0 8.8 5.1e-09 35.9 0.4 4.1 3 1 0 3 3 3 3 Homeodomain PHD PF00628.29 RLN98466.1 - 2.6e-06 27.2 10.7 4.6e-06 26.4 10.7 1.4 1 0 0 1 1 1 1 PHD-finger Homeobox_KN PF05920.11 RLN98466.1 - 0.00065 19.6 1.1 1 9.3 0.0 3.7 3 0 0 3 3 3 2 Homeobox KN domain C1_2 PF03107.16 RLN98466.1 - 0.0038 17.5 1.3 0.0071 16.6 1.3 1.4 1 0 0 1 1 1 1 C1 domain Prok-RING_1 PF14446.6 RLN98466.1 - 0.025 14.5 4.0 0.058 13.3 4.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 RLN98466.1 - 0.03 14.2 7.8 0.062 13.2 7.8 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Homez PF11569.8 RLN98466.1 - 0.055 12.9 1.4 20 4.7 0.0 3.9 4 0 0 4 4 4 0 Homeodomain leucine-zipper encoding, Homez Cytochrom_CIII PF02085.16 RLN98466.1 - 0.37 11.1 5.6 0.97 9.8 5.6 1.6 1 0 0 1 1 1 0 Class III cytochrome C family Zn_ribbon_17 PF17120.5 RLN98466.1 - 0.5 10.0 7.6 0.98 9.1 7.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 RLN98466.1 - 2 8.8 10.8 3.1 8.2 10.8 1.3 1 0 0 1 1 1 0 Ring finger domain PHD_2 PF13831.6 RLN98466.1 - 3 7.5 5.9 5.9 6.5 5.9 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_9 PF13901.6 RLN98466.1 - 3.3 7.6 9.1 6.7 6.6 9.1 1.5 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-RING_5 PF14634.6 RLN98466.1 - 5.2 7.1 11.2 8.2 6.5 11.2 1.3 1 0 0 1 1 1 0 zinc-RING finger domain BRCT_2 PF16589.5 RLN98467.1 - 3.6e-08 33.7 0.0 7.6e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 RLN98467.1 - 8.1e-06 25.9 0.9 0.022 15.0 0.0 2.8 2 0 0 2 2 2 2 Rap1 Myb domain BRCT PF00533.26 RLN98467.1 - 0.0029 18.0 0.0 0.0062 16.9 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rap1_C PF11626.8 RLN98467.1 - 0.056 13.5 0.4 0.67 10.1 0.0 2.9 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SET PF00856.28 RLN98468.1 - 4.7e-08 33.6 0.0 8.1e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 RLN98468.1 - 0.0072 17.0 0.1 0.015 16.0 0.1 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding C2 PF00168.30 RLN98469.1 - 6.5e-15 55.3 0.0 1.6e-06 28.4 0.0 3.6 4 0 0 4 4 4 2 C2 domain C1_1 PF00130.22 RLN98469.1 - 5.8e-06 26.1 5.1 5.8e-06 26.1 5.1 2.8 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pex24p PF06398.11 RLN98469.1 - 0.00019 20.5 0.0 0.093 11.7 0.0 2.2 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin Reticulon PF02453.17 RLN98469.1 - 0.00073 19.5 3.5 0.0017 18.3 0.1 2.3 2 0 0 2 2 2 1 Reticulon C1_2 PF03107.16 RLN98469.1 - 0.0048 17.2 2.8 0.0083 16.4 0.7 2.4 2 0 0 2 2 2 1 C1 domain CBP4 PF07960.11 RLN98469.1 - 0.059 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 CBP4 ACAS_N PF16177.5 RLN98469.1 - 0.15 12.0 0.9 0.5 10.3 0.1 2.3 2 0 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus ATP-synt_ab PF00006.25 RLN98471.1 - 2.8e-67 226.5 0.0 4e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 RLN98471.1 - 1.7e-11 44.5 0.2 3.9e-11 43.3 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF2263 PF10021.9 RLN98472.1 - 0.054 13.9 4.0 1.8 8.9 0.0 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2263) Ribosomal_S21 PF01165.20 RLN98472.1 - 0.2 11.4 11.0 0.66 9.7 11.0 1.9 1 1 0 1 1 1 0 Ribosomal protein S21 Med19 PF10278.9 RLN98472.1 - 1.1 9.2 6.6 1.9 8.4 6.6 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DnaJ PF00226.31 RLN98473.1 - 0.0026 17.9 0.1 0.63 10.2 0.0 2.6 1 1 1 2 2 2 2 DnaJ domain Pkinase PF00069.25 RLN98474.1 - 1.8e-13 50.5 0.0 8e-08 32.0 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain zf-RING_11 PF17123.5 RLN98474.1 - 0.047 13.4 1.5 0.1 12.4 1.5 1.6 1 0 0 1 1 1 0 RING-like zinc finger Dsl1_N PF11988.8 RLN98474.1 - 0.12 11.4 0.6 0.18 10.7 0.6 1.2 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 N terminal zf-ANAPC11 PF12861.7 RLN98474.1 - 0.32 11.1 2.8 0.67 10.0 2.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 RLN98474.1 - 0.34 11.2 6.7 0.79 10.1 6.7 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 RLN98474.1 - 1 9.8 7.8 2.2 8.7 7.8 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 RLN98474.1 - 2.8 7.9 7.8 6.6 6.7 7.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Lipase_GDSL_2 PF13472.6 RLN98475.1 - 4.5e-21 76.0 0.0 5.7e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RLN98475.1 - 2.1e-15 57.3 0.0 3.1e-15 56.7 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PH PF00169.29 RLN98476.1 - 7.4e-09 36.1 0.1 1.3e-08 35.3 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RLN98476.1 - 1.8e-05 25.0 0.5 0.00018 21.7 0.5 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain Cwf_Cwc_15 PF04889.12 RLN98476.1 - 0.026 14.2 11.3 0.042 13.6 11.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 RLN98476.1 - 0.18 11.4 4.8 0.27 10.8 4.8 1.3 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 RLN98476.1 - 0.19 11.7 6.2 0.35 10.8 6.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RXT2_N PF08595.11 RLN98476.1 - 0.22 11.5 1.9 0.37 10.8 1.9 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 RLN98476.1 - 0.8 9.0 12.8 1.2 8.4 12.8 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 RLN98476.1 - 1 7.4 13.6 1.4 6.9 13.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 RLN98476.1 - 1.2 8.4 12.8 1.9 7.8 12.8 1.2 1 0 0 1 1 1 0 BUD22 RPN2_C PF18004.1 RLN98476.1 - 1.7 8.5 5.0 6.1 6.8 5.0 1.7 1 1 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Sigma70_ner PF04546.13 RLN98476.1 - 5.9 6.7 7.2 11 5.9 7.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 RLN98476.1 - 8.1 4.5 11.6 11 4.1 11.6 1.1 1 0 0 1 1 1 0 Nop14-like family Lipase_GDSL_2 PF13472.6 RLN98477.1 - 2.1e-26 93.4 0.1 3e-26 92.9 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RLN98477.1 - 9.1e-18 65.0 0.0 1.2e-17 64.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 RLN98477.1 - 0.031 14.0 0.1 0.089 12.5 0.0 1.7 2 0 0 2 2 2 0 SGNH hydrolase-like domain, acetyltransferase AlgX Lipase_GDSL_2 PF13472.6 RLN98478.1 - 4.5e-44 151.0 0.0 1.5e-21 77.6 0.0 2.6 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RLN98478.1 - 1.5e-35 123.0 0.0 1.7e-17 64.1 0.0 2.5 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 RLN98478.1 - 0.16 11.6 0.0 0.69 9.5 0.0 1.8 2 0 0 2 2 2 0 SGNH hydrolase-like domain, acetyltransferase AlgX MFS_1 PF07690.16 RLN98479.1 - 1e-26 93.8 22.8 8.8e-16 57.8 8.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RLN98479.1 - 6.6e-12 45.0 5.1 3.7e-11 42.5 3.4 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter DUF543 PF04418.12 RLN98479.1 - 0.059 13.4 0.9 0.33 11.0 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Adipogenin PF15202.6 RLN98479.1 - 0.18 11.8 0.6 0.41 10.7 0.6 1.5 1 0 0 1 1 1 0 Adipogenin Lipase_GDSL_2 PF13472.6 RLN98480.1 - 9.3e-25 88.1 0.2 1.1e-24 87.8 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RLN98480.1 - 9.7e-17 61.6 0.0 1.5e-16 61.0 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Thioredoxin PF00085.20 RLN98481.1 - 2e-25 88.7 0.6 2.4e-25 88.5 0.6 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 RLN98481.1 - 4.6e-05 23.8 0.2 0.00021 21.7 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RLN98481.1 - 0.00015 22.1 0.0 0.00034 20.9 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 RLN98481.1 - 0.00051 19.8 0.0 0.00063 19.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 RLN98481.1 - 0.0018 18.2 0.2 0.0022 17.9 0.2 1.2 1 0 0 1 1 1 1 AhpC/TSA family Phosducin PF02114.16 RLN98481.1 - 0.005 15.8 0.0 0.0055 15.7 0.0 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin_4 PF13462.6 RLN98481.1 - 0.024 14.8 0.1 3.6 7.7 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin Redoxin PF08534.10 RLN98481.1 - 0.1 12.3 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Redoxin Glutaredoxin PF00462.24 RLN98481.1 - 0.17 12.1 0.8 0.45 10.8 0.8 1.8 1 1 0 1 1 1 0 Glutaredoxin Ank_2 PF12796.7 RLN98482.1 - 7e-72 238.0 15.1 1.6e-16 60.6 0.1 5.8 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN98482.1 - 8.5e-52 172.9 5.4 1.3e-09 38.4 0.1 6.5 5 1 2 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN98482.1 - 2e-46 150.6 8.8 5.7e-05 23.2 0.0 10.6 11 0 0 11 11 11 9 Ankyrin repeat Ank PF00023.30 RLN98482.1 - 8.8e-43 142.9 10.3 4.4e-05 23.7 0.0 10.0 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.6 RLN98482.1 - 2.7e-41 139.1 14.2 7e-06 26.2 0.1 9.0 3 2 6 9 9 9 9 Ankyrin repeats (many copies) SIR2 PF02146.17 RLN98483.1 - 1.1e-28 100.3 0.0 1.9e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Sir2 family cIII PF08134.11 RLN98483.1 - 0.018 14.8 0.1 0.052 13.3 0.1 1.7 1 0 0 1 1 1 0 cIII protein family Filo_VP35 PF02097.15 RLN98483.1 - 0.076 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Filoviridae VP35 Myosin_head PF00063.21 RLN98484.1 - 4.7e-127 425.0 0.2 6.9e-127 424.5 0.2 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 RLN98484.1 - 1.1e-26 93.4 0.0 3.8e-26 91.7 0.0 2.0 1 0 0 1 1 1 1 MyTH4 domain FERM_M PF00373.18 RLN98484.1 - 1.8e-07 31.6 0.0 5.6e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 FERM central domain Virulence_fact PF13769.6 RLN98484.1 - 0.085 13.1 0.1 0.34 11.1 0.1 2.1 1 0 0 1 1 1 0 Virulence factor Mito_carr PF00153.27 RLN98485.1 - 3.5e-28 97.4 7.2 3.3e-17 62.2 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein SatD PF16264.5 RLN98485.1 - 0.15 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 SatD family (SatD) AMP-binding PF00501.28 RLN98486.1 - 2e-91 306.7 0.0 2.6e-91 306.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN98486.1 - 2.2e-23 83.0 0.4 5.6e-23 81.7 0.4 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 RLN98486.1 - 2.9e-19 68.7 0.4 6e-19 67.7 0.4 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding PF00501.28 RLN98487.1 - 7.3e-91 304.9 0.1 9e-91 304.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN98487.1 - 4.2e-24 85.3 1.3 1e-23 84.1 1.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 RLN98487.1 - 1.3e-19 69.8 0.3 2.8e-19 68.7 0.3 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF1967 PF09269.11 RLN98487.1 - 0.069 13.1 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) TTC5_OB PF16669.5 RLN98487.1 - 0.14 11.8 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain AMP-binding PF00501.28 RLN98488.1 - 2.7e-94 316.2 0.1 3.3e-94 315.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RLN98488.1 - 5e-23 81.9 0.3 1e-22 80.8 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 RLN98488.1 - 1.3e-18 66.7 0.2 2.8e-18 65.6 0.2 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus TruB_N PF01509.18 RLN98489.1 - 6.1e-33 114.3 0.3 8e-21 75.0 0.3 2.1 2 0 0 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) PseudoU_synth_2 PF00849.22 RLN98489.1 - 0.015 15.4 0.0 0.018 15.1 0.0 1.4 1 1 0 1 1 1 0 RNA pseudouridylate synthase Topoisom_bac PF01131.20 RLN98490.1 - 1.8e-98 330.3 0.0 2.3e-98 329.9 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.12 RLN98490.1 - 1.6e-52 175.3 30.3 1.5e-14 53.8 5.4 4.5 4 0 0 4 4 4 4 GRF zinc finger Toprim PF01751.22 RLN98490.1 - 2.3e-11 43.8 0.0 1.3e-10 41.4 0.0 2.2 1 1 0 1 1 1 1 Toprim domain OAD_gamma PF04277.13 RLN98492.1 - 0.14 12.7 0.3 0.21 12.2 0.3 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Glyco_transf_90 PF05686.12 RLN98493.1 - 2.2e-21 76.2 6.2 2.2e-20 72.9 0.7 3.5 2 2 0 2 2 2 2 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 RLN98493.1 - 0.017 15.5 0.0 0.053 13.9 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 EAP30 PF04157.16 RLN98494.1 - 6.5e-36 123.8 0.3 1.1e-35 123.0 0.3 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 RLN98494.1 - 7.9e-16 58.0 0.0 1.5e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 WD40 PF00400.32 RLN98496.1 - 1.8e-46 155.2 20.6 5.4e-07 30.2 0.0 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN98496.1 - 9.9e-12 45.0 0.3 0.00035 20.8 0.0 6.1 2 2 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN98496.1 - 1.5e-07 30.5 5.3 0.046 12.4 0.3 4.9 2 1 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RLN98496.1 - 2.9e-07 29.8 7.6 0.33 9.9 0.1 5.2 2 1 3 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein CEP19 PF14933.6 RLN98496.1 - 4.9e-06 26.9 0.3 7.3e-06 26.4 0.3 1.3 1 0 0 1 1 1 1 CEP19-like protein eIF2A PF08662.11 RLN98496.1 - 0.0041 17.0 0.0 0.33 10.8 0.0 2.8 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A CTP_transf_1 PF01148.20 RLN98497.1 - 7.7e-63 212.7 13.9 9.5e-63 212.4 13.9 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family BRCT PF00533.26 RLN98498.1 - 2e-09 37.7 0.0 2.3e-06 27.9 0.0 3.9 3 2 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 RLN98498.1 - 7.4e-06 26.3 0.0 0.017 15.5 0.0 3.3 2 1 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 RLN98498.1 - 2.4e-05 24.2 0.0 5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 RLN98498.1 - 0.00087 19.1 0.0 1.6 8.6 0.0 2.6 2 0 0 2 2 2 2 Regulator of Ty1 transposition protein 107 BRCT domain GMC_oxred_N PF00732.19 RLN98499.1 - 3.4e-29 102.2 0.0 8e-29 100.9 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 RLN98499.1 - 4.8e-09 36.9 0.3 1e-08 35.8 0.3 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 RLN98499.1 - 9.9e-07 28.2 0.2 1.5e-05 24.3 0.2 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 RLN98499.1 - 1.9e-06 27.3 0.1 0.00023 20.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 RLN98499.1 - 8.1e-06 26.0 0.7 3.5e-05 23.9 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RLN98499.1 - 0.0035 17.0 0.6 0.054 13.1 0.2 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RLN98499.1 - 0.0071 15.6 0.1 0.014 14.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RLN98499.1 - 0.011 14.8 0.3 0.031 13.3 0.3 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 RLN98499.1 - 0.034 13.4 0.1 0.054 12.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 RLN98499.1 - 0.035 12.8 0.7 0.047 12.4 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein ABC_tran PF00005.27 RLN98500.1 - 5.2e-27 95.0 0.0 1.1e-26 94.0 0.0 1.5 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 RLN98500.1 - 4.2e-07 29.6 2.0 9.4e-05 21.9 0.4 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 RLN98500.1 - 0.0013 18.5 0.2 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein MMR_HSR1 PF01926.23 RLN98500.1 - 0.0013 18.8 0.2 0.0043 17.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase DEAD PF00270.29 RLN98500.1 - 0.011 15.5 0.2 0.026 14.3 0.2 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF87 PF01935.17 RLN98500.1 - 0.036 14.2 0.4 0.072 13.2 0.1 1.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_21 PF13304.6 RLN98500.1 - 0.077 12.8 0.1 1.2 8.9 0.1 2.1 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 RLN98500.1 - 0.079 13.0 0.4 0.32 11.0 0.4 1.9 1 1 0 1 1 1 0 Dynamin family AAA_29 PF13555.6 RLN98500.1 - 0.12 12.2 0.2 0.29 10.9 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 RLN98500.1 - 0.19 12.2 0.1 0.4 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_M16_M PF16187.5 RLN98501.1 - 1.7e-27 96.5 0.2 7.6e-27 94.3 0.0 1.9 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 RLN98501.1 - 7.6e-13 48.9 0.0 3.7e-11 43.4 0.0 2.3 2 0 0 2 2 2 1 Peptidase M16 inactive domain Apolipoprotein PF01442.18 RLN98501.1 - 0.024 14.5 0.5 0.043 13.7 0.5 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain NCD1 PF04904.13 RLN98501.1 - 0.05 13.6 0.0 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) Med14 PF08638.11 RLN98502.1 - 4e-45 153.6 0.0 8.9e-45 152.5 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 MnhB PF04039.13 RLN98502.1 - 0.096 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain related to MnhB subunit of Na+/H+ antiporter EF1G PF00647.19 RLN98503.1 - 4.2e-38 129.7 1.8 5.4e-38 129.3 0.1 2.0 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 RLN98503.1 - 6.2e-18 64.9 0.0 1.6e-17 63.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RLN98503.1 - 8.7e-14 51.5 0.1 2e-13 50.4 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RLN98503.1 - 2.4e-10 40.7 0.0 5.5e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN98503.1 - 4.6e-08 33.0 0.0 1.3e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RLN98503.1 - 2.9e-07 30.7 0.0 6.3e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RLN98503.1 - 3.2e-05 24.1 0.0 9.5e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 RLN98503.1 - 0.0014 18.9 0.1 0.0046 17.3 0.0 1.9 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain HTH_ABP1_N PF18107.1 RLN98504.1 - 3.4e-08 33.1 0.4 1.1e-07 31.4 0.4 1.9 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 RLN98504.1 - 7.5e-08 32.3 0.2 1.2e-06 28.4 0.0 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain HTH_32 PF13565.6 RLN98504.1 - 0.045 14.4 0.4 0.045 14.4 0.4 3.8 5 0 0 5 5 5 0 Homeodomain-like domain TMEM247 PF15444.6 RLN98504.1 - 0.96 9.4 6.1 2.8 7.9 6.1 1.7 1 0 0 1 1 1 0 Transmembrane protein 247 eIF3_subunit PF08597.10 RLN98504.1 - 3.9 7.3 10.6 3.2 7.6 8.9 1.6 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit TMPIT PF07851.13 RLN98504.1 - 7.1 5.8 7.3 1.9 7.7 3.7 1.7 2 0 0 2 2 2 0 TMPIT-like protein Ank_2 PF12796.7 RLN98505.1 - 3.6e-29 101.2 1.6 1.5e-09 38.3 0.0 7.2 7 1 1 8 8 8 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN98505.1 - 5.3e-18 65.1 9.0 6.5e-05 23.4 0.5 8.3 6 2 5 11 11 11 5 Ankyrin repeats (many copies) Ank PF00023.30 RLN98505.1 - 9.2e-16 57.5 9.9 0.00078 19.8 0.1 7.6 8 0 0 8 8 8 3 Ankyrin repeat Ank_3 PF13606.6 RLN98505.1 - 1.9e-14 52.3 12.5 0.022 15.3 0.1 9.5 11 0 0 11 11 11 4 Ankyrin repeat Ank_5 PF13857.6 RLN98505.1 - 1.8e-12 47.2 7.1 0.0087 16.4 0.0 7.4 5 3 4 9 9 9 5 Ankyrin repeats (many copies) PerC PF06069.11 RLN98505.1 - 0.1 12.8 0.1 0.35 11.1 0.1 1.9 1 0 0 1 1 1 0 PerC transcriptional activator DUF4034 PF13226.6 RLN98506.1 - 0.0027 17.1 0.2 0.0078 15.6 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4034) Ras PF00071.22 RLN98507.1 - 1e-24 87.0 0.0 5e-22 78.2 0.0 2.2 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RLN98507.1 - 2.4e-13 50.4 0.0 5.5e-08 33.0 0.0 2.5 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 RLN98507.1 - 0.0045 17.4 0.8 0.011 16.1 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain cobW PF02492.19 RLN98507.1 - 0.013 15.1 0.0 0.55 9.8 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.23 RLN98507.1 - 0.036 13.2 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain AAA_22 PF13401.6 RLN98507.1 - 0.037 14.3 0.0 0.074 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 RLN98507.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 RLN98507.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 RLN98507.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 RLN98507.1 - 0.15 12.2 0.1 0.25 11.4 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AA_kinase PF00696.28 RLN98508.1 - 2.3e-33 115.8 0.4 2.9e-33 115.5 0.4 1.1 1 0 0 1 1 1 1 Amino acid kinase family Lac_bphage_repr PF06543.12 RLN98508.1 - 0.032 14.2 2.3 5 7.2 0.5 2.5 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor UCR_TM PF02921.14 RLN98509.1 - 3.8e-14 52.9 0.6 8.4e-14 51.8 0.6 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 RLN98509.1 - 9.6e-13 47.9 0.0 2.1e-12 46.8 0.0 1.6 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Mrx7 PF10906.8 RLN98510.1 - 0.013 15.8 0.1 0.021 15.1 0.1 1.3 1 0 0 1 1 1 0 MIOREX complex component 7 ApoC-I PF04691.12 RLN98510.1 - 0.051 13.5 0.2 0.096 12.6 0.2 1.5 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) HTH_ABP1_N PF18107.1 RLN98512.1 - 2e-08 33.8 1.8 2.2e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 RLN98512.1 - 2.3e-07 30.7 0.3 2.6e-06 27.3 0.1 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain HTH_33 PF13592.6 RLN98512.1 - 0.00086 18.9 0.0 0.0039 16.8 0.0 2.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.6 RLN98512.1 - 0.0055 17.3 0.0 0.0055 17.3 0.0 4.5 3 1 1 4 4 4 1 Homeodomain-like domain TMEM247 PF15444.6 RLN98512.1 - 0.48 10.4 9.4 0.095 12.7 5.6 1.7 2 0 0 2 2 2 0 Transmembrane protein 247 UPF0242 PF06785.11 RLN98512.1 - 5.6 7.0 19.7 19 5.3 19.7 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CCDC-167 PF15188.6 RLN98512.1 - 9.9 6.6 11.9 14 6.1 4.2 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 ABC_tran PF00005.27 RLN98513.1 - 5.4e-12 46.4 0.0 9.1e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN98513.1 - 1.6e-06 28.1 0.0 2.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 RLN98513.1 - 0.017 15.4 0.0 0.19 12.0 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit G-7-MTase PF12803.7 RLN98513.1 - 0.033 13.4 0.2 0.056 12.6 0.2 1.4 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) AAA_15 PF13175.6 RLN98513.1 - 0.071 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain OrfB_Zn_ribbon PF07282.11 RLN98515.1 - 0.0016 18.3 0.1 0.0018 18.1 0.1 1.3 1 1 0 1 1 1 1 Putative transposase DNA-binding domain Mpp10 PF04006.12 RLN98516.1 - 7.8e-130 434.2 34.7 2.5e-109 366.5 36.9 2.0 1 1 1 2 2 2 2 Mpp10 protein MetOD1 PF18546.1 RLN98516.1 - 0.11 12.4 0.4 0.24 11.4 0.4 1.4 1 0 0 1 1 1 0 Metanogen output domain 1 Zip PF02535.22 RLN98517.1 - 2.1e-22 79.8 3.0 3.1e-22 79.2 3.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Cu-oxidase_2 PF07731.14 RLN98517.1 - 7.5e-12 45.2 4.3 6.5e-10 38.9 4.7 2.9 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 RLN98517.1 - 3.9e-09 36.6 3.8 7.3e-06 26.0 0.1 3.5 3 0 0 3 3 3 2 Multicopper oxidase DUF4601 PF15373.6 RLN98517.1 - 0.028 13.4 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) PRELI PF04707.14 RLN98518.1 - 5.2e-39 133.6 0.0 6e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family DUF2505 PF10698.9 RLN98518.1 - 0.00028 21.0 0.1 0.00041 20.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2505) CLASP_N PF12348.8 RLN98519.1 - 1e-06 28.5 0.1 0.00048 19.7 0.0 2.5 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 RLN98519.1 - 1.6e-06 27.8 0.0 0.81 10.1 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 RLN98519.1 - 3e-06 27.5 4.5 0.27 11.7 1.2 4.5 2 2 2 4 4 4 3 HEAT repeats FANCI_S2 PF14676.6 RLN98519.1 - 0.00036 20.9 0.7 0.019 15.3 0.2 2.7 2 0 0 2 2 2 1 FANCI solenoid 2 Cnd1 PF12717.7 RLN98519.1 - 0.088 12.8 0.3 28 4.7 0.0 3.2 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 RLN98519.1 - 0.11 13.2 0.1 1.4 9.6 0.0 2.6 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 RLN98519.1 - 0.11 11.0 0.6 2.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Adaptin N terminal region HEAT PF02985.22 RLN98520.1 - 2.6e-22 77.0 16.7 0.0015 18.6 0.3 10.4 11 1 1 12 12 12 6 HEAT repeat HEAT_2 PF13646.6 RLN98520.1 - 6.6e-15 55.3 0.4 0.0077 16.6 0.2 6.2 3 3 2 6 6 6 3 HEAT repeats Vac14_Fab1_bd PF12755.7 RLN98520.1 - 0.00039 21.0 0.0 0.6 10.7 0.0 4.5 2 1 3 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 RLN98520.1 - 0.0091 16.5 6.1 2.7 8.6 0.0 5.0 4 2 1 5 5 5 1 HEAT-like repeat CLASP_N PF12348.8 RLN98520.1 - 0.075 12.6 0.0 5.1 6.6 0.0 2.7 2 1 0 2 2 2 0 CLASP N terminal Mannosyl_trans3 PF11051.8 RLN98522.1 - 2.4e-32 112.4 0.0 3e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative Neisseria_TspB PF05616.13 RLN98522.1 - 0.1 11.1 2.0 0.14 10.7 2.0 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Trypan_PARP PF05887.11 RLN98522.1 - 0.86 9.6 18.1 1.6 8.7 18.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pneumo_att_G PF05539.11 RLN98522.1 - 0.98 8.9 12.2 1.4 8.4 12.2 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G PARM PF17061.5 RLN98522.1 - 1.8 8.7 16.0 2.6 8.1 16.0 1.2 1 0 0 1 1 1 0 PARM ABC2_membrane_3 PF12698.7 RLN98523.1 - 2.6e-40 138.6 17.9 4.6e-40 137.8 17.9 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 RLN98523.1 - 2.6e-27 96.0 0.0 4.7e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN98523.1 - 8e-08 32.4 0.3 4.7e-06 26.6 0.0 2.4 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RLN98523.1 - 0.043 13.5 0.0 0.37 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF4162 PF13732.6 RLN98523.1 - 0.1 13.3 0.1 37 5.1 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4162) CrgA PF06781.12 RLN98523.1 - 0.2 11.7 2.6 0.35 11.0 1.8 1.9 1 1 0 1 1 1 0 Cell division protein CrgA ABC2_membrane_2 PF12679.7 RLN98523.1 - 6.6 5.9 12.9 16 4.6 9.0 2.7 2 1 0 2 2 2 0 ABC-2 family transporter protein DUF2569 PF10754.9 RLN98523.1 - 7.4 7.0 11.9 1.9 8.9 6.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) SMC_N PF02463.19 RLN98525.1 - 0.001 18.6 0.0 0.0012 18.4 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 RLN98525.1 - 0.0025 18.4 0.4 0.011 16.3 0.1 1.9 2 0 0 2 2 2 1 ABC transporter FERM_N PF09379.10 RLN98525.1 - 0.014 15.3 0.1 0.022 14.7 0.1 1.3 1 0 0 1 1 1 0 FERM N-terminal domain SbcCD_C PF13558.6 RLN98525.1 - 0.12 12.6 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_membrane PF00664.23 RLN98526.1 - 6.4e-54 183.4 0.1 8.4e-54 183.1 0.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN98526.1 - 1.1e-05 26.0 0.5 1.9e-05 25.2 0.5 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 RLN98526.1 - 0.0071 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RLN98526.1 - 0.014 15.2 0.2 0.043 13.6 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain 12TM_1 PF09847.9 RLN98526.1 - 0.099 11.7 0.7 0.94 8.5 0.0 2.3 3 0 0 3 3 3 0 Membrane protein of 12 TMs DUF3007 PF11460.8 RLN98526.1 - 0.4 11.0 1.8 12 6.2 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) Ank_2 PF12796.7 RLN98527.1 - 7.7e-38 129.0 13.2 9.6e-09 35.7 0.5 6.6 1 1 8 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN98527.1 - 1.8e-27 95.4 14.4 4.4e-05 23.9 0.1 10.0 8 3 2 10 10 10 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN98527.1 - 4.3e-26 90.6 21.0 0.01 16.2 0.2 11.7 6 3 6 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN98527.1 - 8.7e-20 68.7 4.9 1.8 9.4 0.0 12.3 14 0 0 14 14 14 5 Ankyrin repeat Ank PF00023.30 RLN98527.1 - 3.2e-05 24.2 6.0 26 5.5 0.0 8.2 4 3 2 6 6 6 1 Ankyrin repeat SAM_3 PF18016.1 RLN98527.1 - 0.016 15.0 0.0 0.72 9.7 0.0 3.2 2 1 1 3 3 3 0 SAM domain (Sterile alpha motif) Beach PF02138.18 RLN98528.1 - 2.4e-115 384.7 0.0 3.3e-115 384.2 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 RLN98528.1 - 2.6e-12 46.7 0.0 1e-10 41.6 0.0 3.1 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.32 RLN98528.1 - 1.3e-11 44.9 10.6 0.021 15.7 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN98528.1 - 0.00039 20.7 0.1 1.2 9.5 0.0 4.2 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain GRAM PF02893.20 RLN98528.1 - 0.0033 17.3 0.0 0.011 15.6 0.0 1.9 2 0 0 2 2 2 1 GRAM domain Ge1_WD40 PF16529.5 RLN98528.1 - 0.007 15.4 0.9 5.7 5.8 0.1 3.4 3 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein GTP_EFTU PF00009.27 RLN98529.1 - 2.3e-44 151.2 0.0 3.2e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 RLN98529.1 - 4.7e-36 124.1 4.3 9.1e-36 123.1 4.3 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 RLN98529.1 - 4.6e-22 78.1 0.0 8.7e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 RLN98529.1 - 1.1e-06 29.0 0.0 2.2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 RLN98529.1 - 5e-06 26.5 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II PH PF00169.29 RLN98530.1 - 3.9e-05 24.1 0.0 8.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 PH domain Syntaxin PF00804.25 RLN98531.1 - 0.31 10.7 0.2 0.47 10.1 0.2 1.1 1 0 0 1 1 1 0 Syntaxin Dicty_REP PF05086.12 RLN98531.1 - 3 5.7 11.2 3.7 5.4 11.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PrsW-protease PF13367.6 RLN98532.1 - 6.6e-11 42.0 9.2 1e-07 31.6 3.1 3.1 3 0 0 3 3 3 2 PrsW family intramembrane metalloprotease Croc_4 PF17691.1 RLN98532.1 - 0.018 15.1 5.1 0.039 14.0 5.1 1.5 1 0 0 1 1 1 0 Contingent replication of cDNA 4 DUF4519 PF15012.6 RLN98532.1 - 0.087 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) PLAC8 PF04749.17 RLN98533.1 - 7.7e-10 39.7 5.7 9.7e-10 39.3 5.7 1.2 1 0 0 1 1 1 1 PLAC8 family ThiF PF00899.21 RLN98534.1 - 5.6e-24 84.8 0.0 1.7e-23 83.3 0.0 1.7 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 RLN98534.1 - 0.0045 17.2 0.2 4.7 7.5 0.1 3.4 3 0 0 3 3 3 1 Ubiquitin-activating enzyme E1 four-helix bundle NAD_binding_7 PF13241.6 RLN98534.1 - 0.016 15.7 0.0 0.046 14.2 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 RLN98534.1 - 0.026 14.6 0.0 0.074 13.1 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SET PF00856.28 RLN98535.1 - 1.4e-16 61.4 0.3 1.5e-14 54.7 0.0 2.7 3 0 0 3 3 3 2 SET domain Myticin-prepro PF10690.9 RLN98535.1 - 2.9 8.2 6.3 7.9 6.8 2.1 2.7 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel Phage_integrase PF00589.22 RLN98536.1 - 9.5e-05 22.3 0.0 0.0007 19.4 0.0 2.6 2 1 0 2 2 2 1 Phage integrase family Phage_int_SAM_4 PF13495.6 RLN98536.1 - 0.092 13.2 0.5 0.092 13.2 0.5 2.6 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain DUF3435 PF11917.8 RLN98536.1 - 0.11 11.4 0.0 3.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) Pkinase_Tyr PF07714.17 RLN98537.1 - 3e-29 102.1 0.0 1.2e-18 67.4 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 RLN98537.1 - 2.2e-23 82.9 0.0 4.7e-23 81.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RLN98537.1 - 0.024 14.0 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 RLN98538.1 - 1.3e-42 145.9 0.0 1.6e-41 142.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN98538.1 - 1.7e-41 142.4 0.0 1.2e-40 139.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain TMEM154 PF15102.6 RLN98538.1 - 0.0016 18.4 0.0 0.0042 17.0 0.0 1.7 1 0 0 1 1 1 1 TMEM154 protein family CD34_antigen PF06365.12 RLN98538.1 - 0.0021 17.7 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 CD34/Podocalyxin family LapA_dom PF06305.11 RLN98538.1 - 0.0058 16.4 0.4 0.016 15.0 0.4 1.7 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain SIT PF15330.6 RLN98538.1 - 0.02 15.4 0.0 0.041 14.3 0.0 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT EphA2_TM PF14575.6 RLN98538.1 - 0.039 14.8 0.2 0.18 12.7 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM100 PF16311.5 RLN98538.1 - 0.055 13.0 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 Pkinase_fungal PF17667.1 RLN98538.1 - 0.07 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF2970 PF11174.8 RLN98538.1 - 0.074 12.9 2.2 0.18 11.7 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Pkinase PF00069.25 RLN98539.1 - 5.2e-46 157.1 0.0 8.1e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN98539.1 - 5.9e-44 150.3 0.0 8.5e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Rax2 PF12768.7 RLN98539.1 - 0.056 12.9 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Cortical protein marker for cell polarity MINDY_DUB PF04424.13 RLN98542.1 - 5.8e-25 87.6 0.1 8.4e-24 83.9 0.1 2.3 2 0 0 2 2 2 1 MINDY deubiquitinase DUF4692 PF15763.5 RLN98542.1 - 9.6 6.7 15.1 0.54 10.7 0.1 2.6 3 0 0 3 3 3 0 Regulator of human erythroid cell expansion (RHEX) Pkinase PF00069.25 RLN98543.1 - 4.4e-56 190.2 0.0 5.8e-56 189.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN98543.1 - 1e-26 93.8 0.0 1.3e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN98543.1 - 6e-09 35.6 0.0 9.1e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RLN98543.1 - 0.00084 19.3 0.0 0.0022 18.0 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RLN98543.1 - 0.0025 16.7 0.0 0.004 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PH PF00169.29 RLN98543.1 - 0.0031 18.0 0.0 0.0067 16.9 0.0 1.5 1 0 0 1 1 1 1 PH domain Pkinase_C PF00433.24 RLN98543.1 - 0.015 16.0 0.3 0.04 14.6 0.3 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain Seadorna_VP7 PF07387.11 RLN98543.1 - 0.032 13.3 0.1 0.052 12.6 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 RLN98543.1 - 0.19 10.6 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain NADH-u_ox-rdase PF10785.9 RLN98544.1 - 9.3e-22 77.5 0.1 1.3e-21 77.1 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit bVLRF1 PF18826.1 RLN98544.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 bacteroidetes VLRF1 release factor TPR_12 PF13424.6 RLN98546.1 - 0.00025 21.3 3.0 0.0031 17.8 0.7 6.9 6 2 2 8 8 8 3 Tetratricopeptide repeat SNAP PF14938.6 RLN98546.1 - 0.00058 19.4 0.1 0.00058 19.4 0.1 2.2 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 RLN98546.1 - 0.0032 17.3 9.9 0.9 9.5 0.1 5.4 4 0 0 4 4 4 2 Tetratricopeptide repeat EF-hand_9 PF14658.6 RLN98546.1 - 0.095 13.0 0.0 1.1 9.6 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain Alginate_exp PF13372.6 RLN98546.1 - 0.1 11.3 4.2 0.22 10.3 1.0 2.2 2 0 0 2 2 2 0 Alginate export TPR_14 PF13428.6 RLN98546.1 - 0.1 13.5 0.1 0.1 13.5 0.1 7.4 6 2 1 7 7 7 0 Tetratricopeptide repeat Dynein_C PF18199.1 RLN98547.1 - 9.9e-91 304.1 0.0 1.2e-90 303.9 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 RLN98547.1 - 1.9e-44 151.4 0.1 2.6e-44 150.9 0.1 1.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain PKD_channel PF08016.12 RLN98548.1 - 1.2e-27 96.6 9.3 9.2e-20 70.7 8.2 3.2 2 1 1 3 3 3 3 Polycystin cation channel Ion_trans PF00520.31 RLN98548.1 - 3.2e-12 46.2 11.4 2.3e-11 43.4 7.5 2.3 2 0 0 2 2 2 2 Ion transport protein cNMP_binding PF00027.29 RLN98549.1 - 7.9e-18 64.3 0.0 3.8e-08 33.3 0.0 3.3 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RLN98549.1 - 1.6e-13 50.5 24.5 1.7e-13 50.4 3.9 3.2 3 1 0 3 3 3 2 Ion transport protein EamA PF00892.20 RLN98549.1 - 2.3 8.4 10.5 1.3 9.2 0.7 3.7 3 0 0 3 3 3 0 EamA-like transporter family Ion_trans_2 PF07885.16 RLN98549.1 - 2.8 8.0 11.8 13 5.8 0.3 4.3 3 0 0 3 3 3 0 Ion channel PSS PF03034.15 RLN98550.1 - 6.1e-104 347.6 13.7 8.2e-104 347.2 13.7 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase PsbN PF02468.15 RLN98550.1 - 0.013 15.3 0.0 0.042 13.7 0.0 1.8 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) AICARFT_IMPCHas PF01808.18 RLN98551.1 - 2e-81 273.7 0.0 2.7e-81 273.2 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 RLN98551.1 - 4.6e-25 87.6 0.0 1e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain CtsR PF05848.11 RLN98551.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 CtsR N-terminal HTH domain DEAD PF00270.29 RLN98552.1 - 6.7e-12 45.5 0.0 2.3e-11 43.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 RLN98552.1 - 0.0017 18.4 0.0 0.019 14.9 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 RLN98552.1 - 0.092 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein CODH_A_N PF18537.1 RLN98553.1 - 0.14 12.2 1.8 2.6 8.1 0.0 3.0 3 0 0 3 3 3 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain E7 PF00527.18 RLN98553.1 - 0.16 12.2 3.9 0.82 9.9 3.9 2.3 1 0 0 1 1 1 0 E7 protein, Early protein PBP1_TM PF14812.6 RLN98553.1 - 0.38 11.2 8.6 0.5 10.8 5.1 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mce4_CUP1 PF11887.8 RLN98553.1 - 0.55 9.6 3.1 2.3 7.6 1.5 2.2 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF948 PF06103.11 RLN98553.1 - 0.91 9.8 7.2 0.93 9.8 1.0 3.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) RPW8 PF05659.11 RLN98553.1 - 1.9 8.2 13.4 3.7 7.2 2.7 3.0 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Med30 PF11315.8 RLN98553.1 - 4.4 7.5 24.1 0.076 13.2 13.1 3.0 1 1 2 3 3 3 0 Mediator complex subunit 30 DUF1664 PF07889.12 RLN98553.1 - 8.2 6.5 15.3 2.1 8.4 5.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) RGS PF00615.19 RLN98554.1 - 2.4e-73 243.9 4.0 5.8e-20 71.7 0.0 4.4 4 0 0 4 4 4 4 Regulator of G protein signaling domain Nop25 PF09805.9 RLN98554.1 - 0.18 12.2 4.9 0.42 11.1 4.9 1.6 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) dsDNA_bind PF01984.20 RLN98555.1 - 1.1e-09 38.5 1.7 1.2e-09 38.4 1.7 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain PaaX PF07848.12 RLN98555.1 - 0.047 13.9 0.0 0.092 13.0 0.0 1.5 1 1 1 2 2 2 0 PaaX-like protein DNA_pol_phi PF04931.13 RLN98555.1 - 0.085 11.0 2.4 0.093 10.8 2.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi Lambda_CIII PF02061.16 RLN98555.1 - 0.2 11.7 0.3 0.31 11.1 0.2 1.4 1 1 0 1 1 1 0 Lambda Phage CIII Med4 PF10018.9 RLN98556.1 - 2.3e-09 37.2 0.7 2.3e-09 37.2 0.7 2.2 2 1 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Rad54_N PF08658.10 RLN98556.1 - 0.09 12.9 1.5 0.091 12.9 0.4 1.6 2 0 0 2 2 2 0 Rad54 N terminal PP2C PF00481.21 RLN98557.1 - 1.8e-31 109.7 0.0 3e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RLN98557.1 - 7.5e-06 25.7 1.5 5.2e-05 23.0 0.0 2.6 2 1 1 3 3 3 1 Protein phosphatase 2C SpoIIE PF07228.12 RLN98557.1 - 0.0048 16.8 0.3 0.016 15.2 0.1 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PigN PF04987.14 RLN98558.1 - 7.7e-125 417.3 27.1 9.6e-125 417.0 27.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 RLN98558.1 - 3.4e-06 26.9 0.2 5.1e-06 26.3 0.2 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RLN98558.1 - 1.1e-05 25.0 0.1 1.7e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 RLN98558.1 - 0.0031 16.9 0.0 0.0049 16.3 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF4148 PF13663.6 RLN98558.1 - 0.12 12.6 0.1 0.85 9.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) zf-C3HC4_2 PF13923.6 RLN98559.1 - 1e-06 28.5 3.2 1e-06 28.5 3.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN98559.1 - 6.4e-06 26.4 3.2 1.3e-05 25.4 0.5 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 RLN98559.1 - 3.7e-05 24.0 1.8 3.7e-05 24.0 1.8 2.6 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 RLN98559.1 - 6e-05 22.9 0.9 6e-05 22.9 0.9 2.2 2 0 0 2 2 2 1 zinc-RING finger domain PX PF00787.24 RLN98559.1 - 0.00011 22.1 1.1 0.00016 21.6 0.4 1.6 2 0 0 2 2 2 1 PX domain zf-C3HC4 PF00097.25 RLN98559.1 - 0.0002 21.2 1.3 0.0002 21.2 1.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RLN98559.1 - 0.004 16.8 0.4 0.004 16.8 0.4 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 RLN98559.1 - 0.041 13.9 0.8 0.041 13.9 0.8 2.0 2 0 0 2 2 1 0 RING-type zinc-finger zf-ribbon_3 PF13248.6 RLN98559.1 - 0.56 9.7 6.4 6.3 6.4 0.6 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-ANAPC11 PF12861.7 RLN98559.1 - 2.4 8.3 7.2 0.83 9.7 0.5 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn-ribbon_8 PF09723.10 RLN98559.1 - 2.5 8.3 6.0 0.34 11.1 0.7 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Importin_rep_4 PF18808.1 RLN98560.1 - 7.9e-12 45.3 3.5 4e-10 39.9 0.0 4.3 4 0 0 4 4 4 1 Importin repeat HEAT_2 PF13646.6 RLN98560.1 - 9.9e-06 25.9 4.1 0.0017 18.7 0.8 9.6 7 3 4 11 11 11 4 HEAT repeats HEAT PF02985.22 RLN98560.1 - 0.00079 19.5 24.7 1 9.8 0.1 10.0 10 0 0 10 10 10 2 HEAT repeat UME PF08064.13 RLN98560.1 - 0.0012 18.7 7.7 11 6.0 0.0 6.0 5 1 0 5 5 5 1 UME (NUC010) domain DUF4704 PF15787.5 RLN98560.1 - 0.029 13.6 1.2 0.12 11.6 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4704) Adaptin_N PF01602.20 RLN98560.1 - 0.042 12.4 0.0 0.95 7.9 0.1 3.0 3 1 0 3 3 3 0 Adaptin N terminal region HEAT_EZ PF13513.6 RLN98560.1 - 0.33 11.5 53.9 0.14 12.7 0.3 11.2 10 2 1 11 11 11 0 HEAT-like repeat Sigma70_ner PF04546.13 RLN98560.1 - 3.5 7.4 9.0 0.36 10.7 1.8 2.4 3 0 0 3 3 3 0 Sigma-70, non-essential region Pkinase_Tyr PF07714.17 RLN98561.1 - 1e-42 146.2 0.0 1.5e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN98561.1 - 1.4e-41 142.6 0.0 2.2e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DOT1 PF08123.13 RLN98561.1 - 4.5e-12 45.9 0.0 7.4e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Pkinase_fungal PF17667.1 RLN98561.1 - 6.7e-05 21.8 0.1 0.00022 20.1 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 RLN98561.1 - 8.9e-05 22.5 5.8 0.00089 19.2 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family PCMT PF01135.19 RLN98561.1 - 0.019 14.7 0.0 0.053 13.3 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_30 PF05430.11 RLN98561.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Kinase-like PF14531.6 RLN98561.1 - 0.14 11.5 0.1 0.35 10.1 0.1 1.6 1 1 0 1 1 1 0 Kinase-like Kinesin PF00225.23 RLN98562.1 - 9.8e-78 261.4 0.0 1.5e-77 260.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RLN98562.1 - 2.6e-13 50.2 0.0 2e-12 47.3 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding DUF87 PF01935.17 RLN98562.1 - 0.044 13.9 0.9 0.089 12.9 0.0 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain Sigma54_activat PF00158.26 RLN98562.1 - 0.087 12.5 0.1 0.21 11.3 0.1 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.6 RLN98562.1 - 0.09 13.1 0.1 0.33 11.2 0.1 2.0 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 RLN98562.1 - 0.55 9.9 3.1 0.26 11.0 0.3 1.8 2 0 0 2 2 2 0 AAA domain Roughex PF06020.11 RLN98562.1 - 0.78 8.8 6.4 2.3 7.3 6.4 1.7 1 0 0 1 1 1 0 Drosophila roughex protein AAA_16 PF13191.6 RLN98562.1 - 0.97 9.8 5.4 0.37 11.2 1.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain Sec1 PF00995.23 RLN98564.1 - 4.5e-101 339.9 0.0 5.2e-101 339.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family TACC_C PF05010.14 RLN98564.1 - 0.00069 19.5 0.1 0.0012 18.7 0.1 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Sigma70_r4 PF04545.16 RLN98564.1 - 0.016 14.7 0.0 0.042 13.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 RLN98564.1 - 0.094 12.4 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Methyltransf_28 PF02636.17 RLN98565.1 - 3.3e-37 128.5 0.0 6e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 RLN98565.1 - 4.7e-05 24.1 0.0 9.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RLN98565.1 - 0.00035 21.2 0.0 0.0012 19.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 RLN98565.1 - 0.001 18.2 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 RLN98565.1 - 0.031 14.1 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 RLN98567.1 - 1.2e-50 172.4 0.0 1.9e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN98567.1 - 3.1e-43 147.9 0.0 4.3e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase VSP PF03302.13 RLN98567.1 - 0.00054 18.9 6.0 0.00097 18.1 6.0 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein SKG6 PF08693.10 RLN98567.1 - 0.016 14.6 4.2 0.035 13.5 4.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kdo PF06293.14 RLN98567.1 - 0.034 13.5 0.1 0.055 12.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Syndecan PF01034.20 RLN98567.1 - 0.037 14.0 0.1 0.076 12.9 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain PTP_tm PF18861.1 RLN98567.1 - 0.13 12.2 0.3 0.24 11.4 0.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J EphA2_TM PF14575.6 RLN98567.1 - 0.15 12.9 0.0 0.35 11.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rav1p_C PF12234.8 RLN98568.1 - 5.4e-45 154.0 0.2 1.4e-41 142.7 0.9 3.0 3 0 0 3 3 3 2 RAVE protein 1 C terminal WD40 PF00400.32 RLN98569.1 - 0.048 14.5 0.1 0.29 12.1 0.0 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat Cupin_8 PF13621.6 RLN98570.1 - 2.9e-14 53.4 1.6 3.8e-11 43.2 0.2 2.2 1 1 1 2 2 2 2 Cupin-like domain JmjC PF02373.22 RLN98570.1 - 1.2e-09 38.6 0.4 1.6e-08 35.0 0.1 2.4 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 RLN98570.1 - 0.019 14.5 0.0 0.03 13.8 0.0 1.4 1 1 0 1 1 1 0 Cupin superfamily protein Cupin_2 PF07883.11 RLN98570.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Cupin domain Ribonuc_L-PSP PF01042.21 RLN98571.1 - 0.0087 16.1 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF1325 PF07039.11 RLN98572.1 - 9.3e-29 100.2 0.0 1.4e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain Agenet PF05641.12 RLN98572.1 - 0.095 13.2 0.2 0.67 10.5 0.1 2.3 2 1 0 2 2 2 0 Agenet domain EF-hand_8 PF13833.6 RLN98573.1 - 1.9e-10 40.4 0.1 2.8e-06 27.1 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN98573.1 - 2e-08 33.2 0.2 0.00037 19.8 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 RLN98573.1 - 2.4e-08 34.3 1.3 0.0028 18.1 0.0 3.6 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 RLN98573.1 - 1.6e-06 27.5 0.3 0.016 15.1 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 RLN98573.1 - 1.3e-05 24.5 0.6 0.00058 19.2 0.0 3.0 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 RLN98573.1 - 0.21 11.9 0.7 1.1e+02 3.2 0.0 3.6 2 1 0 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region Mic1 PF07035.12 RLN98574.1 - 1.4e-17 63.8 0.4 1.2e-16 60.8 0.0 2.3 2 0 0 2 2 2 1 Colon cancer-associated protein Mic1-like Cul7 PF11515.8 RLN98574.1 - 0.14 12.4 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Mouse development and cellular proliferation protein Cullin-7 SNARE PF05739.19 RLN98575.1 - 5.4e-07 29.5 0.5 1.2e-06 28.3 0.5 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin-6_N PF09177.11 RLN98575.1 - 0.039 14.5 0.2 0.062 13.9 0.2 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal FmiP_Thoc5 PF09766.9 RLN98575.1 - 0.063 12.6 1.8 0.086 12.1 1.8 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 Phage_Mu_Gam PF07352.12 RLN98575.1 - 0.089 12.7 1.8 0.13 12.2 1.8 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein TPD52 PF04201.15 RLN98575.1 - 0.1 12.2 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Tumour protein D52 family Nucleoside_tran PF01733.18 RLN98576.1 - 6.1e-21 75.1 10.2 6.1e-17 62.0 0.4 2.8 2 1 1 3 3 3 2 Nucleoside transporter Cyt-b5 PF00173.28 RLN98577.1 - 6.1e-10 39.1 0.0 1.6e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TP6A_N PF04406.14 RLN98577.1 - 0.07 13.1 0.2 0.24 11.4 0.2 1.9 1 0 0 1 1 1 0 Type IIB DNA topoisomerase SPX PF03105.19 RLN98577.1 - 6.8 6.5 11.6 13 5.5 6.2 2.4 2 0 0 2 2 2 0 SPX domain Torus PF16131.5 RLN98578.1 - 1.9e-06 28.5 5.8 6.1e-05 23.7 0.4 2.5 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 RLN98578.1 - 0.0001 22.4 3.0 0.00082 19.6 3.0 2.1 1 1 0 1 1 1 1 Zinc-finger containing family zf_CCCH_4 PF18345.1 RLN98578.1 - 0.0079 16.2 7.5 0.021 14.9 1.4 3.0 2 1 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 RLN98578.1 - 0.049 13.6 5.6 2.4 8.2 0.7 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Acyltransferase PF01553.21 RLN98580.1 - 5.6e-18 64.9 0.0 1.1e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase NAM-associated PF14303.6 RLN98581.1 - 0.0019 18.9 5.3 0.0019 18.9 5.3 2.1 1 1 1 2 2 2 1 No apical meristem-associated C-terminal domain Striatin PF08232.12 RLN98581.1 - 5.8 7.5 13.4 0.86 10.2 2.5 2.9 2 1 1 3 3 3 0 Striatin family TMEM52 PF14979.6 RLN98582.1 - 0.0012 18.7 0.1 0.0025 17.8 0.1 1.5 1 0 0 1 1 1 1 Transmembrane 52 DUF1084 PF06454.11 RLN98582.1 - 0.066 12.6 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1084) zf-CW PF07496.15 RLN98583.1 - 1.2e-06 28.4 0.6 2.2e-06 27.6 0.6 1.5 1 0 0 1 1 1 1 CW-type Zinc Finger zf-CCCH_4 PF18044.1 RLN98584.1 - 5.9e-15 54.7 17.6 1.6e-07 30.9 5.0 2.8 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 RLN98584.1 - 1.2e-12 47.4 20.4 2.6e-06 27.3 6.0 2.8 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 RLN98584.1 - 2.2e-10 41.2 8.8 8.3e-06 26.5 1.5 3.0 1 1 0 2 2 2 2 Torus domain zf-CCCH PF00642.24 RLN98584.1 - 2.3e-10 40.1 16.3 5.6e-05 22.9 3.4 3.0 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CHY PF05495.12 RLN98584.1 - 2e-09 37.8 12.4 2e-09 37.8 12.4 4.2 4 1 1 5 5 5 1 CHY zinc finger Myb_DNA-binding PF00249.31 RLN98584.1 - 1.4e-05 25.2 0.9 0.00075 19.6 0.1 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain RWD PF05773.22 RLN98584.1 - 0.00023 21.4 0.0 0.00054 20.2 0.0 1.7 1 0 0 1 1 1 1 RWD domain zf-CCCH_2 PF14608.6 RLN98584.1 - 0.00028 21.2 17.8 0.026 15.0 4.9 2.8 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Myb_DNA-bind_6 PF13921.6 RLN98584.1 - 0.081 13.2 0.9 0.18 12.1 0.0 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain zf-CCCH_3 PF15663.5 RLN98584.1 - 7.3 6.8 18.4 0.48 10.7 0.4 3.5 4 0 0 4 4 4 0 Zinc-finger containing family FtsZ_C PF12327.8 RLN98585.1 - 1.9e-33 114.7 1.0 1.9e-33 114.7 1.0 2.0 2 0 0 2 2 2 1 FtsZ family, C-terminal domain Tubulin PF00091.25 RLN98585.1 - 6.6e-31 108.0 0.1 4.6e-21 75.9 0.1 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain PX PF00787.24 RLN98586.1 - 1.3e-08 34.8 0.0 2.4e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 PX domain Actin PF00022.19 RLN98588.1 - 2.6e-102 342.5 0.0 4.3e-101 338.5 0.0 2.3 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 RLN98588.1 - 0.15 10.9 0.0 1.2 7.9 0.0 2.0 1 1 0 1 1 1 0 MreB/Mbl protein AAA_23 PF13476.6 RLN98589.1 - 1.6e-19 71.2 1.3 1.6e-19 71.2 1.3 4.7 2 2 1 3 3 3 1 AAA domain SMC_N PF02463.19 RLN98589.1 - 3.2e-12 46.4 14.5 4.7e-11 42.5 13.6 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 RLN98589.1 - 2.9e-07 30.5 9.5 2.9e-07 30.5 9.5 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 RLN98589.1 - 7.5e-05 22.7 0.9 0.00014 21.8 0.2 2.0 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RLN98589.1 - 9e-05 22.1 0.0 0.0002 21.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain CENP-F_leu_zip PF10473.9 RLN98589.1 - 0.0083 16.1 10.4 0.0083 16.1 10.4 6.3 2 2 4 6 6 6 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_16 PF13191.6 RLN98589.1 - 0.34 11.3 0.0 0.34 11.3 0.0 3.4 4 2 0 4 4 4 0 AAA ATPase domain Pkinase PF00069.25 RLN98590.1 - 1.4e-47 162.3 0.0 1.9e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN98590.1 - 2.4e-43 148.3 0.0 3e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Podoplanin PF05808.11 RLN98590.1 - 0.021 14.9 0.1 0.043 13.9 0.1 1.5 1 0 0 1 1 1 0 Podoplanin Haspin_kinase PF12330.8 RLN98590.1 - 0.045 12.7 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain EphA2_TM PF14575.6 RLN98590.1 - 0.049 14.5 0.0 0.11 13.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 RLN98590.1 - 0.053 13.4 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Protocadherin PF08374.11 RLN98590.1 - 0.053 13.5 0.0 0.081 12.9 0.0 1.2 1 0 0 1 1 1 0 Protocadherin Trp_oprn_chp PF09534.10 RLN98590.1 - 0.058 13.2 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TraL PF07178.11 RLN98590.1 - 0.077 13.5 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 TraL protein DUF347 PF03988.12 RLN98590.1 - 0.084 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Pkinase_fungal PF17667.1 RLN98590.1 - 0.093 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 RLN98590.1 - 0.1 12.5 0.6 0.29 11.0 0.4 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Amnionless PF14828.6 RLN98590.1 - 0.18 10.6 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Amnionless Adeno_E3_CR2 PF02439.15 RLN98590.1 - 0.33 10.8 1.5 0.67 9.8 1.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.10 RLN98590.1 - 3.4 7.2 9.4 10 5.7 9.4 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Opi1 PF08618.10 RLN98590.1 - 3.8 6.7 6.6 5.9 6.0 0.2 2.2 2 0 0 2 2 2 0 Transcription factor Opi1 Pkinase_Tyr PF07714.17 RLN98591.1 - 4.8e-08 32.6 0.0 7.1e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN98591.1 - 8e-07 28.7 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TMEM154 PF15102.6 RLN98591.1 - 0.013 15.4 1.5 0.013 15.4 1.5 3.6 1 1 1 2 2 2 0 TMEM154 protein family DcuC PF03606.15 RLN98591.1 - 0.048 12.1 0.5 0.072 11.5 0.5 1.2 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier DUF2627 PF11118.8 RLN98591.1 - 0.11 13.1 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) PepSY_TM_like_2 PF16357.5 RLN98591.1 - 0.14 12.1 0.1 0.14 12.1 0.1 2.0 2 0 0 2 2 2 0 Putative PepSY_TM-like Peptidase_M56 PF05569.11 RLN98591.1 - 0.65 9.1 0.0 0.65 9.1 0.0 1.7 2 0 0 2 2 2 0 BlaR1 peptidase M56 DUF4551 PF15087.6 RLN98591.1 - 1.2 7.9 11.2 1.5 7.5 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TFIIA PF03153.13 RLN98591.1 - 4.5 7.2 8.9 5.7 6.8 8.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mucin PF01456.17 RLN98592.1 - 0.088 12.8 82.8 0.017 15.1 56.6 2.2 1 1 1 2 2 2 0 Mucin-like glycoprotein SOG2 PF10428.9 RLN98593.1 - 0.062 12.5 20.3 0.071 12.3 20.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Glyco_hydro_3 PF00933.21 RLN98594.1 - 2.7e-51 174.9 0.0 3.6e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RLN98594.1 - 6.7e-37 127.4 0.1 1.3e-36 126.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RLN98594.1 - 1.4e-13 50.8 0.4 4.1e-13 49.2 0.2 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain Glyco_hydro_28 PF00295.17 RLN98595.1 - 6e-75 252.3 19.9 6.9e-75 252.1 19.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 NosD PF05048.13 RLN98595.1 - 9.3e-05 21.8 15.2 0.0002 20.7 13.2 2.1 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) ACOX PF01756.19 RLN98596.1 - 4.2e-47 160.0 0.0 5.5e-47 159.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA oxidase 5_3_exonuc PF01367.20 RLN98597.1 - 3.2e-10 40.5 0.0 4.4e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.16 RLN98597.1 - 7.6e-10 38.9 0.0 1.1e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain Pkinase PF00069.25 RLN98599.1 - 4.2e-68 229.6 0.0 5.8e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN98599.1 - 2e-39 135.4 0.0 2.9e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RLN98599.1 - 0.00014 21.3 0.0 0.00091 18.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RLN98599.1 - 0.00092 18.1 0.0 0.0017 17.2 0.0 1.6 1 1 0 1 1 1 1 Fungal protein kinase ACOX PF01756.19 RLN98600.1 - 1.4e-46 158.3 0.1 2.8e-46 157.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 RLN98600.1 - 4.1e-45 153.4 11.3 4.1e-23 82.3 3.0 2.4 2 0 0 2 2 2 2 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 RLN98600.1 - 3.1e-22 78.6 0.0 1.4e-09 38.0 0.0 2.6 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, middle domain DUF3225 PF11533.8 RLN98600.1 - 0.00015 21.4 0.1 0.19 11.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3225) PPARgamma_N PF12577.8 RLN98600.1 - 0.13 12.9 0.0 30 5.4 0.0 2.5 2 0 0 2 2 2 0 PPAR gamma N-terminal region DUF1799 PF08809.11 RLN98600.1 - 0.23 11.7 1.6 32 4.8 0.1 2.9 2 0 0 2 2 2 0 Phage related hypothetical protein (DUF1799) DUF4599 PF15371.6 RLN98600.1 - 0.37 11.3 1.6 14 6.3 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4599) RhoGAP PF00620.27 RLN98600.1 - 8.3 6.2 6.6 12 5.7 0.1 3.4 2 2 1 3 3 3 0 RhoGAP domain ACOX PF01756.19 RLN98601.1 - 2.9e-47 160.6 0.0 3.3e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Acyl-CoA oxidase ThiF PF00899.21 RLN98602.1 - 2.9e-59 200.4 0.1 5.6e-59 199.4 0.1 1.4 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 RLN98602.1 - 3.2e-21 75.7 0.1 8.9e-21 74.3 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain EF-hand_7 PF13499.6 RLN98602.1 - 7.9e-21 74.3 1.1 1.9e-09 37.8 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN98602.1 - 4.9e-19 66.4 0.7 0.0009 18.6 0.0 4.8 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 RLN98602.1 - 7.3e-17 59.8 4.6 0.0002 21.0 0.1 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 RLN98602.1 - 7.5e-11 41.7 5.3 0.00018 21.3 0.1 4.8 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 RLN98602.1 - 2e-10 39.7 0.9 0.041 13.4 0.1 4.8 4 0 0 4 4 4 3 EF hand UBA_e1_thiolCys PF10585.9 RLN98602.1 - 2.5e-10 40.7 0.0 6.9e-09 36.0 0.0 2.6 1 1 0 1 1 1 1 Ubiquitin-activating enzyme active site SPARC_Ca_bdg PF10591.9 RLN98602.1 - 0.0047 17.2 0.0 0.34 11.3 0.0 2.8 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region HEAT PF02985.22 RLN98603.1 - 2.7e-13 48.9 21.6 0.024 14.9 0.1 11.0 11 0 0 11 11 11 4 HEAT repeat HEAT_2 PF13646.6 RLN98603.1 - 3.3e-12 46.6 16.6 0.049 14.0 0.4 7.5 7 1 0 8 8 8 5 HEAT repeats PDZ_6 PF17820.1 RLN98603.1 - 1.7e-09 37.4 1.1 2.2e-05 24.2 0.3 2.9 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 RLN98603.1 - 1.3e-07 31.8 0.0 0.0047 17.2 0.0 2.8 2 0 0 2 2 2 2 PDZ domain UBA_4 PF14555.6 RLN98603.1 - 4.8e-07 29.5 0.1 0.37 10.6 0.0 3.6 3 0 0 3 3 3 2 UBA-like domain PDZ PF00595.24 RLN98603.1 - 5.2e-06 26.7 0.1 0.014 15.8 0.0 2.5 2 0 0 2 2 2 2 PDZ domain Vac14_Fab1_bd PF12755.7 RLN98603.1 - 0.0079 16.8 0.0 0.94 10.1 0.0 3.7 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region CUE PF02845.16 RLN98603.1 - 0.087 12.6 1.2 6.7 6.5 0.0 3.4 4 0 0 4 4 4 0 CUE domain Pox_A_type_inc PF04508.12 RLN98605.1 - 3.8 7.5 5.4 11 6.1 0.0 3.8 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat TFIIA PF03153.13 RLN98605.1 - 9.4 6.1 17.5 16 5.3 17.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAS PF00989.25 RLN98606.1 - 1.1e-182 595.6 6.2 3e-21 75.5 0.0 10.3 10 0 0 10 10 10 10 PAS fold PAS_4 PF08448.10 RLN98606.1 - 2.4e-109 359.3 3.2 3.5e-12 46.5 0.0 10.5 10 0 0 10 10 10 10 PAS fold PAS_9 PF13426.7 RLN98606.1 - 2.5e-97 320.1 14.5 1e-10 41.7 0.0 10.6 11 0 0 11 11 11 10 PAS domain PAS_3 PF08447.12 RLN98606.1 - 2.7e-52 175.0 0.0 4.9e-08 33.1 0.0 10.3 10 0 0 10 10 10 9 PAS fold PAS_8 PF13188.7 RLN98606.1 - 3.4e-31 106.7 5.1 0.012 15.6 0.0 10.5 10 0 0 10 10 10 9 PAS domain HATPase_c PF02518.26 RLN98606.1 - 3.8e-27 95.0 0.0 1.4e-26 93.2 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_10 PF13596.6 RLN98606.1 - 6.1e-22 78.2 3.0 0.022 15.4 0.0 8.8 9 0 0 9 9 9 4 PAS domain Response_reg PF00072.24 RLN98606.1 - 9.8e-21 74.0 0.0 2.5e-20 72.7 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 RLN98606.1 - 4.8e-16 58.6 0.1 4.8e-16 58.6 0.1 2.9 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_7 PF12860.7 RLN98606.1 - 6.1e-14 52.2 9.7 0.5 10.5 0.1 11.3 11 4 0 11 11 11 2 PAS fold Hpt PF01627.23 RLN98606.1 - 7.3e-07 29.4 1.5 3.3e-06 27.3 0.3 2.5 2 0 0 2 2 2 1 Hpt domain sCache_3_3 PF17202.4 RLN98606.1 - 0.003 17.9 4.5 23 5.5 0.0 6.3 7 0 0 7 7 6 0 Single cache domain 3 DUF3189 PF11385.8 RLN98606.1 - 0.0083 16.0 0.1 15 5.4 0.0 4.8 7 0 0 7 7 7 0 Protein of unknown function (DUF3189) DUF5588 PF17826.1 RLN98606.1 - 0.019 13.9 0.3 8.7 5.1 0.0 4.0 5 0 0 5 5 5 0 Family of unknown function (DUF5588) VID27_N PF17748.1 RLN98606.1 - 0.23 11.3 0.5 12 5.7 0.0 3.0 3 0 0 3 3 3 0 VID27 N-terminal region HlyD PF00529.20 RLN98606.1 - 0.9 9.5 4.3 13 5.7 0.0 4.3 5 0 0 5 5 4 0 HlyD membrane-fusion protein of T1SS PUB PF09409.10 RLN98607.1 - 5.8e-12 45.4 0.0 1e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 PUB domain DUF4778 PF16008.5 RLN98607.1 - 0.65 10.0 8.3 0.81 9.7 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Borrelia_P83 PF05262.11 RLN98607.1 - 0.8 8.1 16.8 0.91 7.9 16.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein VSG_B PF13206.6 RLN98607.1 - 0.81 8.9 9.5 1 8.6 9.5 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF2514 PF10721.9 RLN98607.1 - 1 9.4 28.7 4 7.4 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) PH PF00169.29 RLN98608.1 - 7.1e-11 42.6 0.0 0.018 15.5 0.3 4.4 3 1 0 3 3 3 3 PH domain PH_11 PF15413.6 RLN98608.1 - 8e-06 26.2 1.0 2.3 8.7 0.1 5.0 3 3 1 4 4 4 3 Pleckstrin homology domain RVT_1 PF00078.27 RLN98609.1 - 0.0013 18.3 0.4 0.0051 16.4 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 RLN98610.1 - 9.6e-10 38.4 0.2 1.9e-09 37.4 0.2 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 RLN98610.1 - 0.00078 19.3 0.0 0.0016 18.3 0.0 1.5 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase PAS PF00989.25 RLN98613.1 - 9.5e-64 212.4 0.1 7e-19 67.9 0.0 4.1 4 0 0 4 4 4 4 PAS fold PAS_4 PF08448.10 RLN98613.1 - 4.6e-44 149.2 0.4 4.5e-12 46.2 0.0 4.3 4 0 0 4 4 4 4 PAS fold PAS_9 PF13426.7 RLN98613.1 - 4e-43 145.9 0.3 8.9e-13 48.4 0.0 4.1 4 0 0 4 4 4 4 PAS domain PAS_3 PF08447.12 RLN98613.1 - 2.4e-19 69.4 0.0 0.00014 22.1 0.0 4.2 4 0 0 4 4 4 3 PAS fold PAS_8 PF13188.7 RLN98613.1 - 2.4e-18 65.7 0.1 0.00022 21.2 0.0 4.4 4 0 0 4 4 4 4 PAS domain PAS_10 PF13596.6 RLN98613.1 - 1.1e-10 42.0 0.0 0.061 13.9 0.0 3.9 4 0 0 4 4 4 3 PAS domain PAS_7 PF12860.7 RLN98613.1 - 5.5e-08 33.0 0.5 0.18 12.0 0.0 5.0 4 2 0 4 4 4 3 PAS fold sCache_3_2 PF17203.4 RLN98613.1 - 0.0024 18.0 0.1 6.3 6.9 0.0 3.4 3 0 0 3 3 3 1 Single cache domain 3 sCache_3_3 PF17202.4 RLN98613.1 - 0.017 15.6 0.0 2.6 8.5 0.0 3.4 3 0 0 3 3 3 0 Single cache domain 3 Baculo_PEP_C PF04513.12 RLN98615.1 - 3.2e-05 24.0 3.2 7.9e-05 22.7 3.2 1.6 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Dynamitin PF04912.14 RLN98615.1 - 0.0028 17.1 0.5 0.0042 16.5 0.5 1.3 1 0 0 1 1 1 1 Dynamitin zf-CCHC_5 PF14787.6 RLN98615.1 - 0.0054 16.4 1.9 0.011 15.4 1.9 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger DUF948 PF06103.11 RLN98615.1 - 0.032 14.5 3.4 0.13 12.5 3.4 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) ADK_lid PF05191.14 RLN98615.1 - 0.092 12.7 0.8 0.19 11.7 0.8 1.5 1 0 0 1 1 1 0 Adenylate kinase, active site lid DUF4665 PF15679.5 RLN98615.1 - 0.11 13.1 0.4 2.7 8.7 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) C1_1 PF00130.22 RLN98615.1 - 1.5 8.7 6.9 0.84 9.6 0.2 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SlyX PF04102.12 RLN98615.1 - 6.9 7.4 8.3 11 6.7 0.1 3.8 2 1 2 4 4 4 0 SlyX Peptidase_C93 PF06035.11 RLN98617.1 - 0.02 14.7 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP LRR_4 PF12799.7 RLN98618.1 - 8.4e-15 54.7 8.6 1.2e-05 25.6 0.2 3.3 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RLN98618.1 - 5.5e-11 42.3 0.2 2.2e-06 27.3 0.0 2.7 1 1 2 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 RLN98618.1 - 1.7e-08 34.0 5.6 0.00092 18.9 0.6 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 RLN98618.1 - 0.00098 19.4 6.3 1.2 10.0 0.2 3.9 3 1 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.6 RLN98618.1 - 0.016 15.2 0.1 0.38 10.9 0.2 3.1 2 0 0 2 2 2 0 Leucine Rich repeat PCDO_beta_N PF12391.8 RLN98618.1 - 0.12 12.0 0.2 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal DUF3580 PF12117.8 RLN98619.1 - 0.054 13.7 0.1 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3580) V_ATPase_I PF01496.19 RLN98619.1 - 9.2 4.0 7.3 1.2e+02 0.4 0.0 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Tmemb_185A PF10269.9 RLN98620.1 - 0.00023 21.0 4.3 0.0004 20.1 4.3 1.4 1 1 0 1 1 1 1 Transmembrane Fragile-X-F protein Sugar_tr PF00083.24 RLN98621.1 - 9.9e-106 354.3 18.9 9.9e-106 354.3 18.9 1.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 RLN98621.1 - 9.9e-27 93.8 24.6 1.1e-19 70.7 4.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RLN98621.1 - 0.0014 17.2 0.9 0.0014 17.2 0.9 3.3 3 0 0 3 3 3 1 MFS/sugar transport protein BT1 PF03092.16 RLN98621.1 - 0.0087 14.3 0.1 0.0087 14.3 0.1 1.9 3 0 0 3 3 3 1 BT1 family DUF4472 PF14739.6 RLN98621.1 - 0.15 12.8 4.8 0.28 11.9 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Gly-zipper_Omp PF13488.6 RLN98621.1 - 0.55 10.3 3.7 2 8.5 0.5 2.6 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.15 RLN98621.1 - 0.73 9.7 4.2 1.2 9.1 0.9 2.5 2 0 0 2 2 2 0 Glycine zipper 2TM domain DUF423 PF04241.15 RLN98621.1 - 8 6.7 8.9 5.4 7.3 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF423) DHFR_1 PF00186.19 RLN98622.1 - 0.57 9.9 3.2 13 5.4 0.2 2.1 2 0 0 2 2 2 0 Dihydrofolate reductase TIR_2 PF13676.6 RLN98623.1 - 0.14 12.8 0.0 0.19 12.3 0.0 1.2 1 0 0 1 1 1 0 TIR domain Hist_deacetyl PF00850.19 RLN98624.1 - 1.2e-35 123.5 0.0 2.1e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Myc_N PF01056.18 RLN98624.1 - 4 7.2 5.9 1.5 8.7 2.5 1.9 1 1 1 2 2 2 0 Myc amino-terminal region BUD22 PF09073.10 RLN98624.1 - 7.8 5.7 11.5 12 5.1 11.5 1.3 1 0 0 1 1 1 0 BUD22 MFS_2 PF13347.6 RLN98625.1 - 2.3e-06 26.4 6.5 5.8e-06 25.1 6.5 1.6 1 1 0 1 1 1 1 MFS/sugar transport protein Dak2 PF02734.17 RLN98625.1 - 0.19 11.6 0.2 0.31 10.9 0.2 1.2 1 0 0 1 1 1 0 DAK2 domain RRS1 PF04939.12 RLN98628.1 - 1.5e-50 171.2 3.6 1.5e-50 171.2 3.6 2.3 2 1 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) cNMP_binding PF00027.29 RLN98629.1 - 5.5e-05 23.2 0.0 0.0011 19.0 0.0 2.3 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain PH PF00169.29 RLN98630.1 - 0.047 14.2 0.0 0.075 13.5 0.0 1.4 1 0 0 1 1 1 0 PH domain Guanylate_kin PF00625.21 RLN98631.1 - 4.3e-55 186.2 0.0 7e-55 185.5 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase RIIa PF02197.17 RLN98631.1 - 7.4e-06 25.5 0.0 1.7e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit RsgA_GTPase PF03193.16 RLN98631.1 - 0.00028 20.8 0.0 0.00071 19.5 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 RLN98631.1 - 0.00034 20.7 0.0 0.00096 19.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 RLN98631.1 - 0.00091 19.8 0.5 0.0047 17.5 0.5 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RLN98631.1 - 0.0019 18.4 0.0 0.046 13.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 RLN98631.1 - 0.0071 16.9 0.0 0.031 14.8 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 RLN98631.1 - 0.02 15.3 0.0 0.028 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 RLN98631.1 - 0.023 15.0 0.0 0.044 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 RLN98631.1 - 0.051 13.2 0.1 0.42 10.3 0.0 2.3 2 1 1 3 3 3 0 Thymidylate kinase NTPase_1 PF03266.15 RLN98631.1 - 0.066 13.1 0.1 0.12 12.2 0.1 1.5 1 1 0 1 1 1 0 NTPase GGGtGRT PF14057.6 RLN98631.1 - 0.13 11.1 0.1 0.31 9.9 0.1 1.5 1 1 1 2 2 2 0 GGGtGRT protein AAA_29 PF13555.6 RLN98631.1 - 0.17 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cu2_monooxygen PF01082.20 RLN98632.1 - 0.032 14.5 0.0 0.075 13.3 0.0 1.5 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain ABC_membrane PF00664.23 RLN98634.1 - 1.8e-29 103.3 8.2 2.4e-29 102.8 8.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RLN98634.1 - 6.6e-19 68.8 0.0 1.3e-18 67.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RLN98634.1 - 0.0077 15.7 0.2 1.7 8.0 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RLN98634.1 - 0.016 15.6 0.0 0.043 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 RLN98634.1 - 0.021 15.1 0.1 0.14 12.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RLN98634.1 - 0.15 12.4 0.1 0.34 11.3 0.1 1.6 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 RLN98634.1 - 0.22 11.3 0.4 0.46 10.2 0.4 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATP-synt_I PF03899.15 RLN98634.1 - 0.45 10.9 8.8 0.9 9.9 0.0 3.4 3 0 0 3 3 3 0 ATP synthase I chain zf-CCCH PF00642.24 RLN98635.1 - 3.1e-07 30.1 24.9 0.0056 16.6 5.4 4.7 3 2 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 RLN98635.1 - 0.016 15.9 13.0 0.3 11.8 0.3 3.4 2 1 1 3 3 3 0 Torus domain MgtE_N PF03448.17 RLN98635.1 - 0.072 13.7 1.2 0.27 11.9 0.0 2.3 2 1 0 2 2 2 0 MgtE intracellular N domain zf_CCCH_4 PF18345.1 RLN98635.1 - 3.4 7.9 27.0 4.2 7.6 6.4 4.8 4 1 0 4 4 4 0 Zinc finger domain zf-C3H1 PF10650.9 RLN98635.1 - 8.7 6.2 7.3 3.4 7.5 0.1 2.9 3 0 0 3 3 3 0 Putative zinc-finger domain Ank_2 PF12796.7 RLN98636.1 - 2.3e-13 50.5 0.1 2.7e-06 27.9 0.0 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN98636.1 - 3.4e-13 49.8 4.1 0.00016 22.1 0.6 4.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN98636.1 - 2.2e-11 43.7 2.2 0.0052 17.1 0.0 5.6 1 1 5 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN98636.1 - 7.5e-08 32.1 0.0 7.6 7.5 0.0 6.0 6 0 0 6 6 6 2 Ankyrin repeat ADH_zinc_N_2 PF13602.6 RLN98637.1 - 5.4e-19 69.6 0.0 1e-18 68.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 RLN98637.1 - 2.9e-14 53.2 0.0 6.8e-14 52.0 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN98637.1 - 2.3e-09 37.1 0.0 1.1e-08 34.9 0.0 2.0 1 1 2 3 3 3 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 RLN98637.1 - 0.0083 15.4 0.1 0.014 14.7 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF2855 PF11017.8 RLN98637.1 - 0.021 14.6 0.0 0.028 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) CbiJ PF02571.14 RLN98637.1 - 0.033 13.7 0.2 1.5 8.2 0.1 2.1 2 0 0 2 2 2 0 Precorrin-6x reductase CbiJ/CobK Eno-Rase_NADH_b PF12242.8 RLN98637.1 - 0.034 13.9 0.4 0.079 12.7 0.4 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Synapsin PF02078.16 RLN98637.1 - 0.17 12.2 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Synapsin, N-terminal domain WW PF00397.26 RLN98638.1 - 2.4e-08 33.9 1.8 5.1e-08 32.9 1.8 1.6 1 0 0 1 1 1 1 WW domain ADH_zinc_N_2 PF13602.6 RLN98639.1 - 1.8e-17 64.6 0.0 3.1e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 RLN98639.1 - 1.9e-13 50.5 0.0 3.8e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RLN98639.1 - 6.4e-07 29.2 0.0 2.9e-06 27.1 0.0 2.0 1 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Eno-Rase_NADH_b PF12242.8 RLN98639.1 - 0.0039 16.9 0.4 0.0077 16.0 0.4 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AlaDh_PNT_C PF01262.21 RLN98639.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain YjeF_N PF03853.15 RLN98639.1 - 0.041 13.8 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 YjeF-related protein N-terminus CbiJ PF02571.14 RLN98639.1 - 0.054 13.0 0.2 1.3 8.5 0.1 2.1 1 1 1 2 2 2 0 Precorrin-6x reductase CbiJ/CobK Cyanate_lyase PF02560.14 RLN98639.1 - 0.076 12.9 0.0 0.28 11.0 0.0 1.9 1 0 0 1 1 1 0 Cyanate lyase C-terminal domain ADH_zinc_N_2 PF13602.6 RLN98640.1 - 5.7e-20 72.7 0.0 1.2e-19 71.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 RLN98640.1 - 6.2e-15 55.3 0.1 1.6e-14 54.0 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glyco_hydro_6 PF01341.17 RLN98640.1 - 4.6e-10 39.7 0.2 8.3e-10 38.9 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 ADH_N PF08240.12 RLN98640.1 - 7.8e-06 25.7 0.0 2.3e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 RLN98640.1 - 0.037 13.3 0.0 0.082 12.2 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DDE_1 PF03184.19 RLN98642.1 - 5.2e-17 62.0 0.3 7.5e-17 61.5 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_11 PF08279.12 RLN98642.1 - 0.078 12.9 0.3 0.54 10.3 0.0 2.3 2 0 0 2 2 2 0 HTH domain WD40 PF00400.32 RLN98644.1 - 5.4e-21 74.5 0.8 9.4e-06 26.3 0.0 5.4 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN98644.1 - 5.3e-13 49.1 0.3 0.0059 16.9 0.0 4.1 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 RLN98644.1 - 0.001 17.7 0.2 0.46 9.0 0.1 2.4 1 1 2 3 3 3 2 Cytochrome D1 heme domain Frtz PF11768.8 RLN98644.1 - 0.021 13.1 0.0 0.041 12.2 0.0 1.4 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 RLN98644.1 - 0.036 13.4 0.0 6.6 6.0 0.0 2.4 2 1 0 2 2 2 0 WD40-like domain PALB2_WD40 PF16756.5 RLN98644.1 - 0.061 12.2 0.0 0.087 11.7 0.0 1.4 1 1 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain VID27 PF08553.10 RLN98644.1 - 0.099 11.7 0.1 11 5.0 0.0 2.4 2 1 0 2 2 2 0 VID27 C-terminal WD40-like domain TPR_1 PF00515.28 RLN98645.1 - 9.4e-16 56.9 8.9 0.00074 19.2 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 RLN98645.1 - 8.9e-14 51.5 18.0 7.4e-06 26.2 2.3 4.1 2 1 1 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 RLN98645.1 - 4.8e-10 38.8 10.2 0.0045 17.0 1.5 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 RLN98645.1 - 3.3e-09 36.2 3.0 0.094 13.0 0.1 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 RLN98645.1 - 1.5e-08 34.0 15.2 0.023 14.7 0.1 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 RLN98645.1 - 0.00047 19.9 11.5 0.3 11.0 0.4 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 RLN98645.1 - 0.002 17.6 9.0 0.0034 16.8 9.0 1.3 1 0 0 1 1 1 1 MalT-like TPR region CooC_C PF15976.5 RLN98645.1 - 0.0035 17.4 0.0 0.0075 16.3 0.0 1.6 1 0 0 1 1 1 1 CS1-pili formation C-terminal TPR_14 PF13428.6 RLN98645.1 - 0.0038 17.9 6.0 1.6 9.7 1.7 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC5 PF12862.7 RLN98645.1 - 0.04 14.0 4.3 0.74 9.9 0.1 3.3 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_17 PF13431.6 RLN98645.1 - 0.26 11.7 6.4 89 3.8 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat tRNA-synt_2 PF00152.20 RLN98646.1 - 7.6e-71 238.7 0.0 9.5e-71 238.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RLN98646.1 - 5.1e-05 23.2 0.0 9.6e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 RLN98646.1 - 0.0022 18.2 0.0 0.005 17.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 RLN98646.1 - 0.0085 15.6 0.3 2.8 7.4 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Lipase_3 PF01764.25 RLN98647.1 - 5.4e-08 32.8 0.0 1.3e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 RLN98647.1 - 0.0052 16.4 0.2 0.04 13.5 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 RLN98647.1 - 0.02 14.2 0.0 0.07 12.4 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN98647.1 - 0.03 14.9 0.6 0.2 12.2 0.1 2.6 3 0 0 3 3 3 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 RLN98647.1 - 0.039 13.7 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2207 PF09972.9 RLN98647.1 - 0.67 8.7 6.5 9.3 4.9 0.7 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Peptidase_M17 PF00883.21 RLN98648.1 - 3e-73 246.8 3.4 8e-73 245.4 2.0 2.0 2 0 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 RLN98648.1 - 4.8e-10 39.4 0.0 1.3e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Phage_ASH PF10554.9 RLN98648.1 - 0.56 10.6 2.7 0.84 10.0 1.3 2.0 2 0 0 2 2 2 0 Ash protein family Peptidase_M17 PF00883.21 RLN98649.1 - 6e-19 68.4 0.0 6.9e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain DUF4038 PF13204.6 RLN98650.1 - 4.2e-52 177.7 0.0 4.8e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Rotamase_3 PF13616.6 RLN98651.1 - 3e-37 127.7 0.1 3.1e-17 63.2 0.0 2.1 2 0 0 2 2 2 2 PPIC-type PPIASE domain Rotamase PF00639.21 RLN98651.1 - 1.1e-34 119.2 0.3 3.6e-16 59.9 0.0 2.2 2 0 0 2 2 2 2 PPIC-type PPIASE domain Rotamase_2 PF13145.6 RLN98651.1 - 2e-13 51.2 0.0 1.6e-05 25.7 0.0 2.3 2 1 0 2 2 2 2 PPIC-type PPIASE domain SMC_hinge PF06470.13 RLN98651.1 - 0.00012 22.3 0.2 0.027 14.8 0.1 2.1 2 0 0 2 2 2 2 SMC proteins Flexible Hinge Domain DUF3107 PF11305.8 RLN98651.1 - 0.25 11.6 2.7 11 6.4 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3107) HTH_Tnp_Tc5 PF03221.16 RLN98652.1 - 7.7e-09 35.5 0.5 1.4e-08 34.6 0.5 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain MSA-2c PF12238.8 RLN98652.1 - 0.2 11.6 4.3 0.13 12.3 2.0 1.8 2 0 0 2 2 2 0 Merozoite surface antigen 2c Rotamase_3 PF13616.6 RLN98653.1 - 3.3e-12 47.0 0.0 6.4e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 RLN98653.1 - 1.9e-11 44.8 0.2 9e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 PPIC-type PPIASE domain L6_membrane PF05805.12 RLN98653.1 - 0.099 12.2 0.2 0.099 12.2 0.2 1.5 2 0 0 2 2 2 0 L6 membrane protein DPBB_1 PF03330.18 RLN98654.1 - 3.7e-07 30.3 1.8 3.2e-06 27.3 1.8 2.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 RLN98654.1 - 0.0004 20.2 1.5 0.0011 18.8 1.5 1.8 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 RLN98655.1 - 2.4e-06 27.7 0.2 8.2e-06 26.0 0.2 2.0 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 RLN98655.1 - 0.0045 16.8 0.7 0.0083 16.0 0.7 1.5 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 RLN98656.1 - 3.5e-07 30.4 0.4 1.2e-06 28.7 0.0 2.1 2 0 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 RLN98656.1 - 0.00052 19.9 1.0 0.0011 18.8 1.0 1.6 1 0 0 1 1 1 1 Barwin family Cyt-b5 PF00173.28 RLN98657.1 - 6.1e-23 80.8 0.1 2.2e-10 40.5 0.0 2.3 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain ASL_C PF08328.11 RLN98657.1 - 0.065 13.3 0.0 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal Cyt-b5 PF00173.28 RLN98658.1 - 5.6e-22 77.7 0.0 1.6e-10 41.0 0.0 2.3 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain CD36 PF01130.21 RLN98659.1 - 5.7e-45 153.7 0.0 1.3e-43 149.2 0.0 2.3 1 1 0 1 1 1 1 CD36 family DUF4064 PF13273.6 RLN98659.1 - 1.4 9.2 4.8 5.8 7.3 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) CD36 PF01130.21 RLN98660.1 - 0.0043 15.6 0.0 0.0086 14.6 0.0 1.5 1 1 0 1 1 1 1 CD36 family BACON PF13004.7 RLN98660.1 - 0.15 12.1 0.3 0.15 12.1 0.3 1.9 2 0 0 2 2 2 0 Putative binding domain, N-terminal Bac_rhamnosid_N PF08531.10 RLN98661.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain DNA_pol_A PF00476.20 RLN98662.1 - 4.3e-76 256.4 0.2 6.3e-75 252.6 0.1 2.5 2 1 0 2 2 2 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 RLN98662.1 - 3.4e-11 43.2 0.0 1.1e-10 41.5 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease Ni_hydr_CYTB PF01292.20 RLN98663.1 - 1.8 8.1 13.6 1.9 8.1 0.9 2.3 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 Pkinase_Tyr PF07714.17 RLN98664.1 - 1.6e-24 86.6 0.0 1.7e-23 83.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN98664.1 - 2.6e-21 76.2 0.0 4.1e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CD34_antigen PF06365.12 RLN98664.1 - 0.00015 21.5 0.1 0.00024 20.7 0.1 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family TMEM154 PF15102.6 RLN98664.1 - 0.0026 17.7 0.0 0.025 14.5 0.0 2.1 2 0 0 2 2 2 1 TMEM154 protein family Herpes_gE PF02480.16 RLN98664.1 - 0.0027 16.5 0.1 0.0041 15.9 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E MGC-24 PF05283.11 RLN98664.1 - 0.024 15.1 0.6 0.072 13.5 0.1 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FixQ PF05545.11 RLN98664.1 - 0.027 14.4 0.4 0.066 13.2 0.4 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Orf78 PF06024.12 RLN98664.1 - 0.038 14.3 0.0 0.067 13.5 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) TMEM51 PF15345.6 RLN98664.1 - 0.054 13.3 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 Amnionless PF14828.6 RLN98664.1 - 0.17 10.7 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF2207 PF09972.9 RLN98664.1 - 0.17 10.6 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) BatD PF13584.6 RLN98664.1 - 0.2 10.4 0.0 0.3 9.9 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance zf-MYND PF01753.18 RLN98667.1 - 1.1e-05 25.4 9.3 1.1e-05 25.4 9.3 2.2 2 0 0 2 2 2 1 MYND finger SET PF00856.28 RLN98667.1 - 0.00038 20.9 0.2 0.00092 19.6 0.0 1.9 2 0 0 2 2 2 1 SET domain HD_3 PF13023.6 RLN98667.1 - 0.055 13.4 3.7 0.093 12.7 3.4 1.5 1 1 0 1 1 1 0 HD domain PhoD PF09423.10 RLN98668.1 - 2.3e-12 46.6 0.6 4.5e-12 45.7 0.6 1.4 1 1 0 1 1 1 1 PhoD-like phosphatase Phage_int_SAM_1 PF02899.17 RLN98668.1 - 0.065 13.5 0.3 0.065 13.5 0.3 2.3 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain zf-RanBP PF00641.18 RLN98670.1 - 0.022 14.1 6.8 0.038 13.3 6.8 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Ferrochelatase PF00762.19 RLN98674.1 - 1.7e-94 316.5 0.0 2.1e-94 316.2 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 RLN98674.1 - 0.0053 17.1 0.0 17 5.8 0.0 3.2 3 0 0 3 3 3 2 CbiX MinC_N PF05209.13 RLN98675.1 - 0.042 13.8 0.1 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Septum formation inhibitor MinC, N-terminal domain DIMCO_N PF16844.5 RLN98675.1 - 0.05 13.9 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor, N-terminal PIG-L PF02585.17 RLN98676.1 - 1.1e-22 81.1 0.2 1.7e-22 80.4 0.2 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Sds3 PF08598.11 RLN98677.1 - 7.4e-06 26.1 1.3 1.1e-05 25.6 1.3 1.3 1 0 0 1 1 1 1 Sds3-like peroxidase PF00141.23 RLN98678.1 - 7.8e-48 163.2 0.0 1.1e-47 162.6 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF1972 PF09314.11 RLN98678.1 - 0.063 12.8 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1972) Nicastrin PF05450.15 RLN98679.1 - 1.1e-19 70.8 0.3 1.7e-18 67.0 0.3 2.1 1 1 0 1 1 1 1 Nicastrin Ncstrn_small PF18266.1 RLN98679.1 - 2.4e-19 70.0 0.0 3.9e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Nicastrin small lobe Peptidase_M28 PF04389.17 RLN98679.1 - 1.2e-08 34.9 0.2 3.2e-08 33.5 0.1 1.8 2 0 0 2 2 2 1 Peptidase family M28 Bax1-I PF01027.20 RLN98680.1 - 0.011 15.6 37.1 0.014 15.2 37.1 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Cytochrome_P460 PF16694.5 RLN98680.1 - 0.11 12.9 0.1 0.22 11.9 0.1 1.4 1 0 0 1 1 1 0 Cytochrome P460 DEAD PF00270.29 RLN98682.1 - 3.8e-06 26.8 0.4 0.014 15.2 0.1 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN98682.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.8 1 1 0 1 1 1 0 Helicase conserved C-terminal domain CBS PF00571.28 RLN98682.1 - 0.057 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 CBS domain Peptidase_C4 PF00863.19 RLN98685.1 - 0.012 14.9 0.1 0.013 14.8 0.1 1.1 1 0 0 1 1 1 0 Peptidase family C4 ERCC3_RAD25_C PF16203.5 RLN98687.1 - 3.9e-85 285.0 0.1 4.7e-85 284.7 0.1 1.0 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C PF00271.31 RLN98687.1 - 9.6e-11 42.0 0.0 1.6e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RNR_N PF08343.10 RLN98687.1 - 0.075 13.1 0.2 0.23 11.5 0.1 1.8 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal NAD_kinase PF01513.21 RLN98688.1 - 5.2e-63 212.9 0.0 8.3e-63 212.3 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 RLN98688.1 - 0.0033 17.0 0.0 0.007 16.0 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DMAP_binding PF06464.11 RLN98688.1 - 0.034 15.0 0.1 0.067 14.0 0.1 1.5 1 0 0 1 1 1 0 DMAP1-binding Domain DUF3584 PF12128.8 RLN98689.1 - 0.0029 15.2 11.7 0.0029 15.2 11.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) GIDE PF12483.8 RLN98689.1 - 0.0073 15.7 0.9 0.012 15.1 0.1 1.6 2 0 0 2 2 2 1 E3 Ubiquitin ligase PIN_12 PF16289.5 RLN98689.1 - 0.036 14.5 5.1 0.05 14.1 5.1 1.3 1 0 0 1 1 1 0 PIN domain MqsR_toxin PF15723.5 RLN98689.1 - 0.16 12.4 2.3 0.22 11.9 1.0 1.9 1 1 1 2 2 2 0 Motility quorum-sensing regulator, toxin of MqsA PRKCSH-like PF12999.7 RLN98689.1 - 0.27 11.0 11.9 0.33 10.7 2.3 2.1 1 1 1 2 2 2 0 Glucosidase II beta subunit-like ApoO PF09769.9 RLN98689.1 - 0.62 10.0 2.5 1.1 9.2 0.2 2.0 2 0 0 2 2 2 0 Apolipoprotein O Acetyltransf_11 PF13720.6 RLN98689.1 - 1.9 9.0 4.8 9.1 6.8 0.2 2.2 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Exonuc_VII_L PF02601.15 RLN98689.1 - 2 7.9 10.6 2.5 7.6 10.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Methyltr_RsmB-F PF01189.17 RLN98690.1 - 0.0016 18.1 0.1 0.0016 18.1 0.1 2.2 2 1 0 2 2 2 1 16S rRNA methyltransferase RsmB/F CCSAP PF15748.5 RLN98690.1 - 0.12 12.5 19.1 0.15 12.2 19.1 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DDHD PF02862.17 RLN98690.1 - 0.13 12.4 10.2 0.16 12.1 10.2 1.1 1 0 0 1 1 1 0 DDHD domain TERB2 PF15101.6 RLN98690.1 - 0.26 11.3 10.3 0.36 10.9 10.3 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Vfa1 PF08432.10 RLN98690.1 - 0.41 11.0 20.9 0.6 10.4 20.9 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SAGA-Tad1 PF12767.7 RLN98690.1 - 0.44 10.3 9.2 0.5 10.1 9.2 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Spt20 PF12090.8 RLN98690.1 - 0.44 10.1 14.1 0.64 9.6 14.1 1.3 1 0 0 1 1 1 0 Spt20 family SprA-related PF12118.8 RLN98690.1 - 0.59 9.2 20.3 0.77 8.8 20.3 1.1 1 0 0 1 1 1 0 SprA-related family ALMT PF11744.8 RLN98690.1 - 1 8.2 7.9 1 8.1 7.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 RLN98690.1 - 1.3 6.8 11.8 1.5 6.6 11.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MCM_bind PF09739.9 RLN98690.1 - 1.6 7.1 11.3 1.6 7.1 11.3 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor RR_TM4-6 PF06459.12 RLN98690.1 - 1.7 8.4 20.7 2.1 8.1 20.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 RLN98690.1 - 1.9 7.2 12.5 2 7.1 12.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein VIR_N PF15912.5 RLN98690.1 - 2 7.9 11.5 2.4 7.7 11.5 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal FAM60A PF15396.6 RLN98690.1 - 2.5 8.1 13.0 2.7 7.9 13.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RP-C_C PF11800.8 RLN98690.1 - 2.7 8.0 13.1 3.2 7.8 13.1 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region GREB1 PF15782.5 RLN98690.1 - 5.9 3.9 12.4 6.4 3.8 12.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LMBR1 PF04791.16 RLN98690.1 - 7.5 5.3 7.6 8.4 5.2 7.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Presenilin PF01080.17 RLN98690.1 - 8.1 5.1 19.6 9.6 4.8 19.6 1.0 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.16 RLN98690.1 - 8.7 5.8 18.0 12 5.3 18.0 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DNA_pol_B PF00136.21 RLN98691.1 - 7.3e-89 298.6 0.0 9.8e-89 298.2 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 RLN98691.1 - 5.8e-08 32.3 0.0 1.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 RLN98691.1 - 0.014 15.8 9.8 0.037 14.5 9.8 1.7 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta FYVE PF01363.21 RLN98691.1 - 2.8 8.1 8.2 10 6.4 8.2 2.0 1 1 0 1 1 1 0 FYVE zinc finger Taxilin PF09728.9 RLN98692.1 - 0.0067 15.6 27.9 0.025 13.8 2.3 2.1 1 1 1 2 2 2 2 Myosin-like coiled-coil protein FUSC PF04632.12 RLN98692.1 - 5.8 5.3 10.9 4.1 5.8 9.2 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family YabA PF06156.13 RLN98692.1 - 8.9 7.0 20.3 0.35 11.5 0.8 3.2 1 1 2 3 3 3 0 Initiation control protein YabA DUF3543 PF12063.8 RLN98694.1 - 8.4e-14 51.5 0.1 8.4e-13 48.3 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Rx_N PF18052.1 RLN98694.1 - 0.14 12.4 0.3 0.31 11.3 0.1 1.6 2 0 0 2 2 2 0 Rx N-terminal domain MIT PF04212.18 RLN98694.1 - 0.23 11.6 2.5 2.4 8.3 0.0 3.3 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain zf-PARP PF00645.18 RLN98695.1 - 1.7e-05 25.6 1.4 1.7e-05 25.6 1.4 2.4 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF5340 PF17275.2 RLN98695.1 - 0.081 13.1 1.3 0.89 9.7 1.9 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5340) MoaC PF01967.21 RLN98696.1 - 9.9e-50 168.2 0.1 1.2e-49 167.9 0.1 1.0 1 0 0 1 1 1 1 MoaC family Chorion_S16 PF05836.12 RLN98696.1 - 0.025 14.8 0.0 0.053 13.8 0.0 1.5 2 0 0 2 2 2 0 Chorion protein S16 SNF2_N PF00176.23 RLN98697.1 - 6.1e-46 156.7 0.0 1e-45 156.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RLN98697.1 - 3.8e-24 85.2 0.1 1.4e-20 73.6 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain HDA2-3 PF11496.8 RLN98697.1 - 3.1e-06 26.6 0.1 6.4e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 RLN98697.1 - 1.1e-05 24.9 0.1 1.9e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 RLN98697.1 - 0.027 14.2 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Nop10p PF04135.12 RLN98698.1 - 4e-22 78.0 0.5 5.6e-22 77.5 0.5 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Ras PF00071.22 RLN98699.1 - 2.3e-24 85.8 0.2 2e-23 82.8 0.2 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RLN98699.1 - 4.9e-19 68.7 0.0 8.5e-19 67.9 0.0 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RLN98699.1 - 6.8e-06 25.6 0.1 1.6e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 RLN98699.1 - 0.0046 16.2 0.0 0.34 10.0 0.0 2.0 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 RLN98699.1 - 0.013 15.6 0.0 0.019 15.0 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase Pox_A32 PF04665.12 RLN98699.1 - 0.016 14.7 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein Septin PF00735.18 RLN98699.1 - 0.017 14.4 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 RLN98699.1 - 0.033 14.6 0.0 0.045 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 RLN98699.1 - 0.035 13.6 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 RLN98699.1 - 0.064 13.3 0.0 0.085 12.9 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 RLN98699.1 - 0.087 12.5 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RLN98699.1 - 0.091 12.9 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 RLN98699.1 - 0.096 12.0 0.1 0.24 10.7 0.1 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DAP3 PF10236.9 RLN98699.1 - 0.097 11.8 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 RLN98699.1 - 0.1 12.5 0.2 0.13 12.2 0.2 1.1 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 RLN98699.1 - 0.11 11.7 0.1 0.13 11.4 0.1 1.1 1 0 0 1 1 1 0 NB-ARC domain Amino_oxidase PF01593.24 RLN98700.1 - 1.9e-15 57.2 0.1 4.1e-08 33.0 0.0 2.9 2 1 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RLN98700.1 - 2.9e-09 37.0 0.0 7.4e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RLN98700.1 - 0.0019 17.8 0.0 0.74 9.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 RLN98700.1 - 0.062 12.0 0.0 0.4 9.3 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.14 RLN98700.1 - 0.063 12.5 0.0 0.33 10.1 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 RLN98700.1 - 0.066 13.2 0.0 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 RLN98700.1 - 0.12 11.5 1.3 0.79 8.7 0.1 2.2 1 1 1 2 2 2 0 Lycopene cyclase protein RNA_pol_L_2 PF13656.6 RLN98701.1 - 9.1e-22 76.6 0.2 3.1e-19 68.5 0.2 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 RLN98701.1 - 0.00041 19.7 0.0 0.0022 17.4 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CHCH PF06747.13 RLN98702.1 - 4.5e-08 33.0 6.4 6.9e-08 32.4 6.4 1.3 1 0 0 1 1 1 1 CHCH domain DUF1962 PF09227.10 RLN98702.1 - 0.078 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1962) COX6B PF02297.17 RLN98702.1 - 0.26 11.6 4.9 0.4 10.9 4.9 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 RLN98702.1 - 0.28 11.5 3.0 0.47 10.8 3.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Totivirus_coat PF05518.11 RLN98702.1 - 0.96 7.4 9.9 1.1 7.2 9.9 1.1 1 0 0 1 1 1 0 Totivirus coat protein CX9C PF16860.5 RLN98702.1 - 1.5 8.9 7.4 2.5 8.2 7.4 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, MSA-2c PF12238.8 RLN98702.1 - 4.4 7.3 13.1 0.033 14.2 3.8 1.9 1 1 1 2 2 2 0 Merozoite surface antigen 2c DUF2868 PF11067.8 RLN98702.1 - 8.7 5.7 10.9 13 5.2 10.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2868) GTP_EFTU PF00009.27 RLN98703.1 - 2.1e-64 216.7 0.5 3.2e-64 216.0 0.5 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RLN98703.1 - 3.5e-05 23.8 0.1 0.00016 21.7 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 RLN98703.1 - 0.083 12.5 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Ras family Dynamin_N PF00350.23 RLN98703.1 - 0.11 12.5 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Dynamin family SRPRB PF09439.10 RLN98703.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PLDc_2 PF13091.6 RLN98704.1 - 2.8e-14 53.1 0.0 5.5e-14 52.2 0.0 1.5 1 1 0 1 1 1 1 PLD-like domain PLDc PF00614.22 RLN98704.1 - 6.2e-08 32.5 0.3 1.1e-07 31.7 0.3 1.5 1 0 0 1 1 1 1 Phospholipase D Active site motif ABC2_membrane PF01061.24 RLN98705.1 - 4.8e-60 202.6 74.0 2.3e-32 112.2 27.5 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 RLN98705.1 - 7.7e-34 117.1 0.1 1.5e-15 57.9 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 RLN98705.1 - 2.3e-08 34.6 0.2 0.0043 17.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 RLN98705.1 - 4.3e-08 32.8 0.8 0.0066 16.2 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 RLN98705.1 - 2.7e-07 30.7 0.2 0.043 13.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system PDR_CDR PF06422.12 RLN98705.1 - 4.8e-07 29.6 5.0 5.5e-05 23.0 0.0 3.4 3 0 0 3 3 3 1 CDR ABC transporter RsgA_GTPase PF03193.16 RLN98705.1 - 7.8e-07 29.1 0.4 0.013 15.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 RLN98705.1 - 1.2e-05 24.8 0.5 0.034 13.6 0.1 3.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RLN98705.1 - 5.5e-05 23.5 0.0 0.48 10.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 RLN98705.1 - 0.00013 21.8 0.2 0.27 11.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 RLN98705.1 - 0.00015 22.3 0.0 0.86 10.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 RLN98705.1 - 0.00031 20.4 0.5 0.45 10.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 RLN98705.1 - 0.00041 19.7 0.7 0.065 12.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.29 RLN98705.1 - 0.00066 20.1 0.1 1.7 9.1 0.1 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 RLN98705.1 - 0.0013 19.3 0.1 0.31 11.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 RLN98705.1 - 0.0024 17.0 15.1 0.0024 17.0 15.1 3.6 2 2 0 3 3 3 1 ABC-2 family transporter protein AAA_33 PF13671.6 RLN98705.1 - 0.0037 17.4 0.0 2.7 8.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 RLN98705.1 - 0.0046 17.0 2.2 0.64 10.1 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 RLN98705.1 - 0.0076 16.2 0.8 0.69 9.8 0.0 2.4 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 NACHT PF05729.12 RLN98705.1 - 0.0076 16.2 1.7 3.3 7.6 0.3 2.8 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.17 RLN98705.1 - 0.015 15.4 3.2 0.84 9.7 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_19 PF13245.6 RLN98705.1 - 0.015 15.6 0.2 4 7.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain PDR_assoc PF08370.11 RLN98705.1 - 0.016 15.0 0.2 0.016 15.0 0.2 3.6 3 0 0 3 3 2 0 Plant PDR ABC transporter associated AAA_28 PF13521.6 RLN98705.1 - 0.016 15.5 0.2 1.1 9.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RLN98705.1 - 0.025 15.0 0.1 7.5 7.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 RLN98705.1 - 0.029 14.1 0.1 9.2 5.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 RLN98705.1 - 0.042 13.9 0.4 2.3 8.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Roc PF08477.13 RLN98705.1 - 0.077 13.2 0.1 14 5.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 RLN98705.1 - 0.078 12.6 1.1 2.8 7.5 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 RLN98705.1 - 0.12 12.4 0.5 3.4 7.7 0.1 2.6 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 RLN98705.1 - 0.15 11.2 0.6 0.43 9.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 RLN98705.1 - 0.15 11.8 0.6 4.9 6.9 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.9 RLN98705.1 - 0.21 10.8 0.1 1.5 7.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 RLN98705.1 - 0.39 10.2 1.3 3.6 7.0 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2769 PF10967.8 RLN98709.1 - 0.5 11.1 4.0 0.52 11.0 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2769) Sporozoite_P67 PF05642.11 RLN98709.1 - 0.61 8.1 5.3 0.72 7.9 5.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1664 PF07889.12 RLN98710.1 - 0.49 10.4 3.3 0.94 9.5 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 RLN98710.1 - 2.2 7.4 3.9 3.7 6.7 3.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein DMRL_synthase PF00885.19 RLN98711.1 - 1.1e-43 148.4 0.2 1.4e-43 148.1 0.2 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase ESCRT-II PF05871.12 RLN98712.1 - 3.8e-37 127.6 0.0 4.9e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Trypsin_2 PF13365.6 RLN98713.1 - 1.5e-05 26.0 0.0 2.5e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Tub PF01167.18 RLN98714.1 - 1.3e-49 169.1 0.0 6e-49 167.0 0.0 1.9 1 1 0 1 1 1 1 Tub family PDZ_6 PF17820.1 RLN98714.1 - 3.2e-08 33.3 0.0 6.4e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RLN98714.1 - 0.0022 18.3 0.0 0.0042 17.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain K-box PF01486.17 RLN98714.1 - 0.15 12.2 0.4 0.3 11.3 0.4 1.5 1 0 0 1 1 1 0 K-box region GCV_T PF01571.21 RLN98716.1 - 3.1e-81 272.5 0.0 5.5e-81 271.7 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 RLN98716.1 - 2e-20 72.5 0.5 4.4e-20 71.4 0.5 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SPOB_ab PF14682.6 RLN98716.1 - 0.042 13.9 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal cNMP_binding PF00027.29 RLN98717.1 - 2.7e-26 91.4 0.1 3.2e-13 49.6 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF5435 PF17503.2 RLN98717.1 - 0.033 13.9 0.1 0.073 12.8 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5435) Ion_trans PF00520.31 RLN98717.1 - 0.048 12.9 2.8 0.23 10.7 2.8 2.0 1 1 0 1 1 1 0 Ion transport protein Ion_trans_2 PF07885.16 RLN98717.1 - 0.095 12.7 0.5 0.23 11.4 0.5 1.7 1 0 0 1 1 1 0 Ion channel GoLoco PF02188.17 RLN98717.1 - 0.22 11.1 0.9 14 5.3 0.1 3.0 3 0 0 3 3 3 0 GoLoco motif Profilin PF00235.19 RLN98718.1 - 0.024 14.9 0.0 0.042 14.1 0.0 1.7 1 1 0 1 1 1 0 Profilin FSA_C PF10479.9 RLN98718.1 - 2.1 6.4 4.2 2.3 6.2 4.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus WD40 PF00400.32 RLN98719.1 - 1.4e-29 101.7 3.7 1.1e-07 32.4 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN98719.1 - 0.00063 20.0 0.1 4.2 7.7 0.0 3.7 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN98719.1 - 0.001 17.8 0.2 0.86 8.2 0.0 3.0 3 0 0 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 RLN98719.1 - 0.012 15.7 0.0 6.5 6.9 0.0 3.2 2 1 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region EMP24_GP25L PF01105.24 RLN98721.1 - 0.46 10.4 3.7 0.7 9.8 1.5 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD PBECR5 PF18814.1 RLN98721.1 - 8.4 6.3 10.3 20 5.0 10.3 1.6 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 EMP24_GP25L PF01105.24 RLN98722.1 - 6.1e-20 71.9 0.7 6.5e-20 71.8 0.7 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TPR_2 PF07719.17 RLN98723.1 - 0.022 14.8 1.0 0.056 13.6 1.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 RLN98723.1 - 0.16 11.9 1.1 0.32 10.9 1.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat FAD_binding_6 PF00970.24 RLN98724.1 - 3e-34 117.3 0.0 4.8e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 RLN98724.1 - 6.8e-25 87.8 0.0 1e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 RLN98724.1 - 0.0041 17.2 0.0 0.0058 16.8 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 RLN98724.1 - 0.022 15.0 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Complex1_LYR PF05347.15 RLN98725.1 - 3.1e-07 30.3 0.0 5.2e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 RLN98725.1 - 0.078 13.7 0.2 0.098 13.4 0.2 1.3 1 1 0 1 1 1 0 Complex1_LYR-like DUF832 PF05734.11 RLN98725.1 - 0.079 12.4 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) Myotub-related PF06602.14 RLN98726.1 - 2.4e-147 490.5 0.1 4e-147 489.8 0.1 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.21 RLN98726.1 - 2.1e-17 63.0 9.9 5.6e-17 61.6 9.9 1.8 1 0 0 1 1 1 1 FYVE zinc finger Y_phosphatase PF00102.27 RLN98726.1 - 7.4e-06 25.7 0.1 1.3e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 RLN98726.1 - 8.1e-06 25.7 0.1 1.7e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 RLN98726.1 - 0.0011 19.0 1.4 0.0031 17.5 0.0 2.3 3 0 0 3 3 3 1 Tyrosine phosphatase family GRAM PF02893.20 RLN98726.1 - 0.0022 17.9 0.1 0.012 15.5 0.1 2.1 1 1 0 1 1 1 1 GRAM domain 3-PAP PF12578.8 RLN98726.1 - 0.0026 17.5 0.0 0.0072 16.1 0.0 1.7 1 0 0 1 1 1 1 Myotubularin-associated protein NAD_binding_6 PF08030.12 RLN98727.1 - 7.2e-13 48.9 0.0 2.1e-12 47.4 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 RLN98727.1 - 5.5e-09 36.2 9.7 1.7e-08 34.6 9.7 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Orthoreo_P10 PF07204.11 RLN98727.1 - 0.018 15.0 0.1 0.018 15.0 0.1 3.1 3 0 0 3 3 3 0 Orthoreovirus membrane fusion protein p10 NAD_binding_1 PF00175.21 RLN98727.1 - 0.13 12.9 0.0 0.25 12.0 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF2371 PF10177.9 RLN98728.1 - 0.092 12.9 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Glyco_transf_20 PF00982.21 RLN98729.1 - 7e-179 595.4 0.0 9.1e-179 595.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 RLN98729.1 - 5e-37 127.3 0.0 9e-37 126.4 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_hydro_3_C PF01915.22 RLN98729.1 - 0.13 12.2 0.0 2.9 7.8 0.0 2.4 2 1 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain Nop14 PF04147.12 RLN98729.1 - 0.75 7.9 12.2 1.1 7.4 12.2 1.1 1 0 0 1 1 1 0 Nop14-like family Roughex PF06020.11 RLN98729.1 - 1.4 7.9 8.0 3.2 6.8 8.0 1.6 1 0 0 1 1 1 0 Drosophila roughex protein SDA1 PF05285.12 RLN98729.1 - 3 7.2 11.7 4.6 6.6 11.7 1.2 1 0 0 1 1 1 0 SDA1 Herpes_pp85 PF04637.12 RLN98729.1 - 4.3 5.6 6.7 8.1 4.7 6.7 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Rhomboid PF01694.22 RLN98730.1 - 2e-08 34.4 11.3 4.7e-05 23.4 2.4 3.5 4 0 0 4 4 4 3 Rhomboid family GBP PF02263.19 RLN98731.1 - 3.3e-63 213.4 0.0 3.3e-63 213.4 0.0 2.3 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 RLN98731.1 - 1.7e-10 40.8 12.3 1.7e-10 40.8 12.3 3.5 1 1 2 3 3 3 1 Guanylate-binding protein, C-terminal domain MMR_HSR1 PF01926.23 RLN98731.1 - 0.0016 18.5 0.0 0.007 16.4 0.0 2.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF5082 PF16888.5 RLN98731.1 - 8.7 6.6 31.7 5 7.4 14.0 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) LRR_6 PF13516.6 RLN98732.1 - 4.7e-32 107.3 21.5 0.00013 21.7 0.1 11.8 12 0 0 12 12 12 8 Leucine Rich repeat LRR_4 PF12799.7 RLN98732.1 - 6e-12 45.6 19.6 0.03 14.8 0.5 8.0 6 2 2 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN98732.1 - 4e-07 29.7 22.1 0.32 10.8 3.6 7.8 5 3 2 7 7 7 4 Leucine rich repeat LRR_1 PF00560.33 RLN98732.1 - 1e-05 25.4 13.9 1.2e+02 3.9 0.0 8.9 9 1 0 9 9 9 0 Leucine Rich Repeat LRR_2 PF07723.13 RLN98732.1 - 0.0034 18.0 1.6 1.1 10.0 0.0 4.0 5 0 0 5 5 5 1 Leucine Rich Repeat SSURE PF11966.8 RLN98732.1 - 0.11 12.3 1.9 0.47 10.2 0.2 2.8 3 0 0 3 3 3 0 Fibronectin-binding repeat Pkinase PF00069.25 RLN98733.1 - 4.2e-79 265.6 0.0 5.1e-79 265.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN98733.1 - 6.4e-35 120.7 0.0 8.6e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RLN98733.1 - 6e-06 25.3 0.0 1.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RLN98733.1 - 0.00047 19.6 0.0 0.00084 18.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 RLN98733.1 - 0.00096 18.6 0.1 0.0014 18.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 RLN98733.1 - 0.021 13.8 0.1 0.033 13.2 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Proteasome PF00227.26 RLN98735.1 - 1.8e-36 125.4 0.2 9.4e-35 119.8 0.2 2.2 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RLN98735.1 - 1.9e-10 40.2 0.4 4.5e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RrnaAD PF00398.20 RLN98738.1 - 2.9e-05 23.3 0.0 4.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 RLN98738.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MULE PF10551.9 RLN98739.1 - 4.8e-12 46.1 0.1 1.3e-11 44.7 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 RLN98739.1 - 0.021 15.5 0.1 0.054 14.2 0.1 1.7 1 0 0 1 1 1 0 FAR1 DNA-binding domain Paf1 PF03985.13 RLN98739.1 - 2.3 7.2 3.9 3.6 6.5 3.9 1.2 1 0 0 1 1 1 0 Paf1 C2 PF00168.30 RLN98740.1 - 7.1e-73 241.5 6.4 2.9e-16 59.6 0.0 10.1 12 0 0 12 12 12 7 C2 domain PH PF00169.29 RLN98740.1 - 7.1e-16 58.6 0.3 1.7e-14 54.2 0.1 3.1 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 RLN98740.1 - 0.016 15.6 4.0 0.096 13.1 0.6 3.4 2 1 0 2 2 2 0 Pleckstrin homology domain DUF4110 PF13422.6 RLN98740.1 - 5.7 7.1 8.2 10 6.3 0.6 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4110) DUF4497 PF14924.6 RLN98741.1 - 1.7e-13 51.0 0.0 3.1e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4497) CLP1_P PF16575.5 RLN98742.1 - 2.7e-40 138.2 0.0 4.4e-40 137.5 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 RLN98742.1 - 0.0018 18.8 0.0 0.0034 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RLN98742.1 - 0.0057 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 RLN98742.1 - 0.0088 16.4 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 RLN98742.1 - 0.042 14.2 0.0 0.09 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 RLN98742.1 - 0.044 13.5 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 RLN98742.1 - 0.065 12.6 0.0 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family 2OG-Fe_Oxy_2 PF10014.9 RLN98742.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe dioxygenase AAA_33 PF13671.6 RLN98742.1 - 0.11 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 RLN98742.1 - 0.15 12.1 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain RCC1 PF00415.18 RLN98743.1 - 3.1e-75 248.6 14.3 7.5e-15 55.3 0.0 8.3 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN98743.1 - 5.3e-47 156.7 23.2 1.8e-09 37.2 0.1 7.6 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat SIS_2 PF13580.6 RLN98743.1 - 0.047 13.7 0.3 16 5.5 0.0 3.0 2 1 0 2 2 2 0 SIS domain Hira PF07569.11 RLN98743.1 - 0.048 13.4 0.1 64 3.2 0.0 3.8 4 0 0 4 4 4 0 TUP1-like enhancer of split Glutaredoxin PF00462.24 RLN98744.1 - 4.4e-10 39.6 0.0 8.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin SH3_2 PF07653.17 RLN98744.1 - 2e-09 37.0 0.0 5.3e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 RLN98744.1 - 7.6e-07 28.9 0.0 1.7e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RLN98744.1 - 0.00013 21.5 0.0 0.00033 20.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain DUF836 PF05768.14 RLN98744.1 - 0.082 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Coilin_N PF15862.5 RLN98744.1 - 0.17 11.7 0.1 0.17 11.7 0.1 6.3 1 1 6 7 7 7 0 Coilin N-terminus SapB_2 PF03489.17 RLN98745.1 - 7.6e-22 77.1 18.8 0.00061 19.8 0.1 7.5 8 0 0 8 8 8 5 Saposin-like type B, region 2 SapB_1 PF05184.15 RLN98745.1 - 4.9e-06 26.4 12.6 0.15 12.1 0.0 6.0 6 0 0 6 6 6 3 Saposin-like type B, region 1 HTH_23 PF13384.6 RLN98745.1 - 0.014 15.2 0.0 16 5.4 0.0 4.1 4 0 0 4 4 4 0 Homeodomain-like domain Thioredoxin_3 PF13192.6 RLN98745.1 - 0.18 11.9 4.1 23 5.2 0.1 3.9 4 0 0 4 4 4 0 Thioredoxin domain EF-hand_7 PF13499.6 RLN98746.1 - 3.7e-17 62.5 1.5 4.3e-08 33.5 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN98746.1 - 5.2e-16 56.9 0.9 0.0012 18.2 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 RLN98746.1 - 1.3e-15 55.9 2.1 3.1e-05 23.6 0.0 4.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 RLN98746.1 - 5.9e-09 35.0 1.3 0.0063 16.0 0.1 4.6 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 RLN98746.1 - 7.7e-09 35.3 4.9 0.0009 19.0 0.0 4.3 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RLN98746.1 - 0.05 13.9 0.0 13 6.1 0.0 2.6 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RLN98746.1 - 0.18 11.8 0.0 3.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand PDZ_6 PF17820.1 RLN98748.1 - 9.8e-07 28.5 1.0 3.1e-06 27.0 0.5 2.2 2 0 0 2 2 2 1 PDZ domain UBA_4 PF14555.6 RLN98748.1 - 1.1e-06 28.4 0.0 0.029 14.2 0.0 2.5 2 0 0 2 2 2 2 UBA-like domain PDZ_2 PF13180.6 RLN98748.1 - 0.00019 21.7 0.0 0.00056 20.2 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RLN98748.1 - 0.05 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 PDZ domain CUE PF02845.16 RLN98748.1 - 0.061 13.0 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 CUE domain SPX PF03105.19 RLN98748.1 - 0.42 10.5 1.7 0.62 9.9 1.7 1.2 1 0 0 1 1 1 0 SPX domain DNA_pol_phi PF04931.13 RLN98748.1 - 6.4 4.8 5.7 12 3.9 5.7 1.4 1 0 0 1 1 1 0 DNA polymerase phi ThiF PF00899.21 RLN98749.1 - 1.5e-58 198.0 0.1 2.2e-58 197.5 0.1 1.2 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 RLN98749.1 - 5e-21 75.1 0.0 9.9e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 RLN98749.1 - 2.6e-11 44.0 0.7 1.2e-07 32.0 0.0 2.4 2 1 0 3 3 3 2 Ubiquitin-activating enzyme active site HEAT PF02985.22 RLN98750.1 - 2.8e-16 58.2 15.4 0.016 15.4 0.1 10.7 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.6 RLN98750.1 - 1.4e-13 51.0 11.1 0.17 12.3 0.0 6.9 6 1 0 7 7 7 5 HEAT repeats PDZ PF00595.24 RLN98750.1 - 0.0031 17.8 0.0 0.0069 16.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain HEAT_EZ PF13513.6 RLN98750.1 - 0.039 14.5 2.7 45 4.7 0.0 4.7 4 1 0 4 4 4 0 HEAT-like repeat PDZ_2 PF13180.6 RLN98750.1 - 0.086 13.2 0.2 0.23 11.8 0.0 1.8 2 0 0 2 2 2 0 PDZ domain PDZ_6 PF17820.1 RLN98750.1 - 0.098 12.5 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Jnk-SapK_ap_N PF09744.9 RLN98752.1 - 0.015 15.6 6.8 0.015 15.6 6.8 3.8 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Seryl_tRNA_N PF02403.22 RLN98752.1 - 0.023 14.9 3.3 0.023 14.9 3.3 3.4 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF2951 PF11166.8 RLN98752.1 - 2.4 8.4 10.9 0.22 11.8 0.2 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2951) DUF818 PF05677.12 RLN98753.1 - 2.8e-08 33.1 0.0 4.5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_1 PF00561.20 RLN98753.1 - 3.1e-08 33.6 0.2 7.1e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RLN98753.1 - 1.2e-07 32.5 0.2 1.2e-07 32.5 0.2 2.7 2 1 0 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RLN98753.1 - 7.1e-06 25.5 0.0 1.9e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 RLN98753.1 - 0.012 14.5 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 RLN98753.1 - 0.096 12.5 0.0 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold PA PF02225.22 RLN98754.1 - 1.4e-06 28.3 0.0 4e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 PA domain Glyco_transf_41 PF13844.6 RLN98754.1 - 0.0016 17.0 0.0 0.092 11.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 41 Acyl-CoA_ox_N PF14749.6 RLN98755.1 - 1.4e-30 106.4 0.0 1.7e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 RLN98755.1 - 0.0059 16.8 0.0 0.0095 16.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 RLN98755.1 - 0.01 16.5 0.0 0.017 15.8 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain DUF4477 PF14780.6 RLN98756.1 - 1.5e-08 34.5 9.1 8.7e-08 32.0 9.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4477) DprA_WH PF17782.1 RLN98756.1 - 0.00048 20.2 0.8 0.0025 17.9 0.2 2.3 2 0 0 2 2 2 1 DprA winged helix domain APG17 PF04108.12 RLN98756.1 - 0.046 12.8 0.7 0.063 12.4 0.5 1.4 1 1 0 1 1 1 0 Autophagy protein Apg17 UQ_con PF00179.26 RLN98757.1 - 4.2e-12 45.9 0.2 4.9e-10 39.2 0.0 2.7 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme Nsp1_C PF05064.13 RLN98758.1 - 5.5e-08 32.6 1.2 5.5e-08 32.6 1.2 2.2 1 1 1 2 2 2 1 Nsp1-like C-terminal region Snapin_Pallidin PF14712.6 RLN98758.1 - 0.0011 19.3 13.6 0.0049 17.3 7.7 3.1 1 1 3 4 4 4 2 Snapin/Pallidin Herpes_UL25 PF01499.16 RLN98758.1 - 0.0053 15.3 1.3 0.0061 15.2 1.3 1.1 1 0 0 1 1 1 1 Herpesvirus UL25 family DUF4164 PF13747.6 RLN98758.1 - 0.014 15.6 7.0 0.25 11.7 1.9 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) DUF1664 PF07889.12 RLN98758.1 - 0.016 15.3 9.7 0.16 12.0 5.1 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DASH_Dad2 PF08654.10 RLN98758.1 - 0.016 15.6 5.7 1.1 9.7 1.1 2.5 2 1 0 2 2 2 0 DASH complex subunit Dad2 FlaC_arch PF05377.11 RLN98758.1 - 0.02 15.3 6.0 0.45 10.9 0.1 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) TACC_C PF05010.14 RLN98758.1 - 0.02 14.7 7.3 0.023 14.5 6.6 1.3 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Laminin_II PF06009.12 RLN98758.1 - 0.021 14.8 8.6 0.055 13.5 3.1 2.1 1 1 1 2 2 2 0 Laminin Domain II Fez1 PF06818.15 RLN98758.1 - 0.021 15.3 6.4 0.027 14.9 6.4 1.1 1 0 0 1 1 1 0 Fez1 CHAD PF05235.14 RLN98758.1 - 0.031 14.3 0.6 0.038 14.0 0.6 1.2 1 0 0 1 1 1 0 CHAD domain Syntaxin PF00804.25 RLN98758.1 - 0.035 13.8 6.0 0.4 10.3 0.5 2.0 1 1 1 2 2 2 0 Syntaxin Spc7 PF08317.11 RLN98758.1 - 0.04 12.8 9.2 0.12 11.3 9.2 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF948 PF06103.11 RLN98758.1 - 0.08 13.2 7.9 2.6 8.4 7.4 3.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1978 PF09321.10 RLN98758.1 - 0.09 12.1 6.6 0.18 11.1 6.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1978) DMSP_lyase PF16867.5 RLN98758.1 - 0.11 12.1 0.7 1.1 8.9 0.3 2.0 1 1 1 2 2 2 0 Dimethlysulfonioproprionate lyase DASH_Dad4 PF08650.10 RLN98758.1 - 0.17 11.9 6.2 0.52 10.3 1.1 3.1 2 2 1 3 3 3 0 DASH complex subunit Dad4 BST2 PF16716.5 RLN98758.1 - 0.22 12.1 6.6 0.12 13.0 1.4 2.2 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 TMPIT PF07851.13 RLN98758.1 - 0.22 10.7 4.8 0.47 9.6 4.8 1.6 1 1 0 1 1 1 0 TMPIT-like protein Mod_r PF07200.13 RLN98758.1 - 0.23 11.5 8.6 2.8 8.1 0.7 2.2 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein KIP1 PF07765.12 RLN98758.1 - 0.26 11.4 4.8 1.6 8.9 0.7 2.4 2 0 0 2 2 2 0 KIP1-like protein DUF4200 PF13863.6 RLN98758.1 - 0.36 11.2 6.0 0.84 10.1 4.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Fib_alpha PF08702.10 RLN98758.1 - 0.42 10.8 8.9 2.7 8.2 2.2 2.3 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family CLZ PF16526.5 RLN98758.1 - 0.44 10.9 9.0 2.4 8.6 0.6 2.9 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Frataxin_Cyay PF01491.16 RLN98758.1 - 0.46 10.6 5.4 1.8 8.7 0.8 2.2 1 1 1 2 2 2 0 Frataxin-like domain Enkurin PF13864.6 RLN98758.1 - 0.5 10.8 4.8 0.67 10.4 1.2 2.3 1 1 1 2 2 2 0 Calmodulin-binding DUF4795 PF16043.5 RLN98758.1 - 0.57 9.8 10.7 1.5 8.4 10.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PRKG1_interact PF15898.5 RLN98758.1 - 0.58 11.1 7.1 0.44 11.5 5.3 1.7 2 0 0 2 2 1 0 cGMP-dependent protein kinase interacting domain UPF0449 PF15136.6 RLN98758.1 - 0.97 9.9 6.4 4.1 7.9 4.0 2.4 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Prominin PF05478.11 RLN98758.1 - 1.1 7.1 7.6 3.1 5.7 7.8 1.4 1 1 0 1 1 1 0 Prominin DUF16 PF01519.16 RLN98758.1 - 1.2 9.6 9.1 2.4 8.7 8.3 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 bZIP_1 PF00170.21 RLN98758.1 - 1.3 9.2 8.3 1.1 9.5 0.5 2.6 3 0 0 3 3 2 0 bZIP transcription factor XhlA PF10779.9 RLN98758.1 - 2.8 8.2 6.6 4.7 7.5 0.3 2.5 2 1 0 2 2 2 0 Haemolysin XhlA Tweety PF04906.13 RLN98758.1 - 3 6.4 6.1 2.9 6.5 0.5 2.0 1 1 1 2 2 2 0 Tweety KELK PF15796.5 RLN98758.1 - 4.6 7.8 8.3 1.4 9.4 2.5 2.7 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Cnn_1N PF07989.11 RLN98758.1 - 9.3 6.5 10.3 16 5.7 6.6 2.6 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 CAP PF00188.26 RLN98759.1 - 4.6e-21 76.0 3.9 5.5e-21 75.7 3.9 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 RLN98760.1 - 1.2e-19 71.4 4.2 2.3e-19 70.5 4.2 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Arrestin_C PF02752.22 RLN98762.1 - 1.7e-11 44.7 0.0 5.7e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 RLN98762.1 - 1.2e-05 25.4 0.0 0.001 19.2 0.0 2.6 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 RLN98762.1 - 0.023 14.4 0.1 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 Arrestin_N terminal like DIOX_N PF14226.6 RLN98763.1 - 4.2e-21 75.9 0.0 9.8e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 RLN98763.1 - 7.5e-19 68.1 0.0 1.1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CAP PF00188.26 RLN98764.1 - 1.6e-15 58.0 1.3 2.2e-15 57.6 1.3 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 RLN98765.1 - 5.7e-19 69.2 4.3 5.7e-19 69.2 4.3 1.5 2 0 0 2 2 2 1 Cysteine-rich secretory protein family CAP PF00188.26 RLN98766.1 - 1.3e-19 71.3 2.1 1.3e-19 71.3 2.1 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family PAP1 PF08601.10 RLN98766.1 - 0.14 11.8 15.4 0.092 12.5 14.3 1.3 1 1 0 1 1 1 0 Transcription factor PAP1 MGC-24 PF05283.11 RLN98766.1 - 9.9 6.6 9.7 19 5.7 9.7 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PMSR PF01625.21 RLN98767.1 - 0.014 15.6 0.1 0.048 13.8 0.0 1.9 2 0 0 2 2 2 0 Peptide methionine sulfoxide reductase DNA_pol_A_exo1 PF01612.20 RLN98767.1 - 0.016 14.9 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 3'-5' exonuclease GBP PF02263.19 RLN98769.1 - 1e-07 31.5 0.0 1.2e-07 31.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_16 PF13191.6 RLN98769.1 - 0.12 12.7 0.0 0.19 12.1 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain Metallophos PF00149.28 RLN98770.1 - 3.3e-15 57.2 2.8 1.1e-09 39.1 0.2 2.6 3 0 0 3 3 3 2 Calcineurin-like phosphoesterase ANAPC4_WD40 PF12894.7 RLN98770.1 - 0.13 12.6 0.1 1.3 9.4 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain SPX PF03105.19 RLN98771.1 - 8e-14 52.3 0.9 6.5e-08 32.9 0.1 2.5 2 0 0 2 2 2 2 SPX domain zf-RING_UBOX PF13445.6 RLN98771.1 - 2.8e-06 27.2 9.6 5.4e-06 26.3 9.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 RLN98771.1 - 2.9e-06 27.5 13.5 6.1e-06 26.5 13.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RLN98771.1 - 7.1e-06 25.8 12.0 1.4e-05 24.8 12.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Metallophos PF00149.28 RLN98771.1 - 2e-05 25.2 0.0 3.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-C3HC4_3 PF13920.6 RLN98771.1 - 2.8e-05 23.9 10.9 4.7e-05 23.2 10.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RLN98771.1 - 0.00012 22.1 12.0 0.00023 21.2 12.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 RLN98771.1 - 0.00026 20.8 13.0 0.00052 19.8 13.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RLN98771.1 - 0.00036 20.4 11.6 0.00097 19.0 11.6 1.7 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RLN98771.1 - 0.0036 17.1 14.0 0.018 14.9 14.2 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 RLN98771.1 - 0.23 11.3 8.4 0.72 9.7 8.4 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 RLN98771.1 - 0.34 11.2 10.3 0.69 10.2 10.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 RLN98771.1 - 0.89 9.7 5.5 1.7 8.8 5.5 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_5 PF17121.5 RLN98771.1 - 3.8 7.5 6.4 8.4 6.4 6.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Peptidase_M13_N PF05649.13 RLN98772.1 - 5.2e-80 270.0 0.0 7.8e-80 269.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 RLN98772.1 - 7.3e-65 218.4 0.1 1e-64 217.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.18 RLN98772.1 - 0.076 12.8 0.1 0.58 9.9 0.0 2.3 3 0 0 3 3 3 0 Peptidase family M48 RNase_T PF00929.24 RLN98773.1 - 2e-13 51.2 0.0 4.5e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 RLN98773.1 - 0.00032 20.4 0.0 0.0012 18.6 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease Roughex PF06020.11 RLN98773.1 - 0.11 11.6 1.3 2.8 7.0 0.1 2.2 2 0 0 2 2 2 0 Drosophila roughex protein Draxin PF15550.6 RLN98773.1 - 1.1 9.0 11.1 2.1 8.1 11.1 1.3 1 0 0 1 1 1 0 Draxin Pneumo_att_G PF05539.11 RLN98773.1 - 4.3 6.8 8.9 1.3 8.6 5.5 1.6 2 0 0 2 2 2 0 Pneumovirinae attachment membrane glycoprotein G Presenilin PF01080.17 RLN98773.1 - 7.1 5.3 5.8 12 4.5 5.8 1.3 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 RLN98773.1 - 8.9 6.2 11.5 1.1 9.2 7.4 1.5 2 0 0 2 2 2 0 Protein Family FAM60A Ank_2 PF12796.7 RLN98774.1 - 1e-35 122.2 5.1 1.5e-11 44.7 0.0 4.3 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN98774.1 - 9e-23 80.4 1.2 1.6e-06 28.5 0.1 4.8 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN98774.1 - 1.6e-21 74.1 0.8 0.00051 20.3 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 RLN98774.1 - 1.3e-17 63.7 5.3 7.7e-05 22.9 0.0 5.6 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 RLN98774.1 - 7.2e-11 42.0 8.3 0.00022 21.5 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat DHHC PF01529.20 RLN98774.1 - 1.7e-09 37.9 5.5 1.7e-09 37.9 5.5 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF4231 PF14015.6 RLN98774.1 - 0.19 12.2 2.5 0.2 12.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) PGI PF00342.19 RLN98775.1 - 2.3e-195 649.9 0.0 2.6e-195 649.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase RCC1 PF00415.18 RLN98776.1 - 2e-51 172.4 18.5 2.3e-12 47.4 0.3 7.1 7 0 0 7 7 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RLN98776.1 - 8e-28 95.6 23.3 5.3e-07 29.3 2.5 6.9 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Methyltransf_25 PF13649.6 RLN98776.1 - 1.6e-09 38.3 0.6 6e-08 33.3 0.1 3.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN98776.1 - 3.5e-08 33.4 0.0 1.1e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain LRR_4 PF12799.7 RLN98776.1 - 6.7e-08 32.7 0.0 2.5 8.7 0.1 7.2 6 2 3 9 9 9 1 Leucine Rich repeats (2 copies) Methyltransf_12 PF08242.12 RLN98776.1 - 1.1e-07 32.5 0.0 8e-07 29.7 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain LRR_6 PF13516.6 RLN98776.1 - 2.5e-07 30.2 17.5 10 6.4 0.2 10.5 11 0 0 11 11 11 1 Leucine Rich repeat Methyltransf_11 PF08241.12 RLN98776.1 - 2.6e-07 31.2 0.0 1.3e-06 28.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 RLN98776.1 - 5.5e-07 29.4 0.0 0.0016 18.1 0.0 2.8 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F MTS PF05175.14 RLN98776.1 - 1.3e-05 24.8 0.0 5e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 RLN98776.1 - 2.7e-05 24.1 0.0 8.3e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN98776.1 - 0.18 11.1 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family LRR_1 PF00560.33 RLN98776.1 - 0.75 10.6 6.9 47 5.1 0.0 5.3 6 0 0 6 6 4 0 Leucine Rich Repeat RRM_1 PF00076.22 RLN98777.1 - 1.6e-15 56.7 0.0 7e-11 41.8 0.0 4.0 4 1 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RLN98777.1 - 0.0057 16.5 0.0 0.022 14.6 0.0 1.9 2 0 0 2 2 2 1 Occluded RNA-recognition motif DUF436 PF04260.12 RLN98777.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF436) TPR_2 PF07719.17 RLN98778.1 - 2.3e-11 42.9 20.1 0.00058 19.8 0.1 8.3 9 0 0 9 9 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN98778.1 - 1.1e-10 41.6 27.4 7.3e-06 26.1 0.9 5.1 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 RLN98778.1 - 2.3e-10 40.8 11.3 0.0005 20.5 0.1 5.9 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 RLN98778.1 - 1e-08 35.2 2.5 0.00061 19.9 0.1 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN98778.1 - 1.4e-05 25.6 7.6 0.1 13.3 0.1 5.3 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 RLN98778.1 - 2.5e-05 24.6 9.5 0.053 14.2 0.1 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 RLN98778.1 - 0.00013 22.5 6.8 1.8 9.6 0.1 6.3 5 3 1 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 RLN98778.1 - 0.00013 21.7 2.7 0.78 9.7 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 RLN98778.1 - 0.00024 21.3 9.2 0.61 10.4 0.0 6.1 5 2 1 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN98778.1 - 0.00053 20.0 2.7 4 7.6 0.1 3.8 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 RLN98778.1 - 0.0011 18.7 14.5 0.0064 16.3 0.0 6.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 RLN98778.1 - 0.002 18.2 5.1 1.2 9.6 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN98778.1 - 0.002 18.0 4.0 0.71 10.0 0.1 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 RLN98778.1 - 0.0044 17.0 2.3 0.0044 17.0 2.3 4.6 2 2 2 4 4 4 2 Putative TPR-like repeat Glyco_transf_20 PF00982.21 RLN98779.1 - 1.9e-124 415.9 0.0 1.1e-123 413.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 RLN98779.1 - 3.5e-47 160.5 0.0 5.5e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 RLN98779.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase LRR_6 PF13516.6 RLN98780.1 - 2e-10 39.9 7.8 0.015 15.3 0.3 5.2 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 RLN98780.1 - 0.0065 16.9 1.8 0.1 13.1 0.1 2.9 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN98780.1 - 0.03 14.1 2.5 0.35 10.7 0.1 2.8 3 0 0 3 3 3 0 Leucine rich repeat Pkinase_Tyr PF07714.17 RLN98781.1 - 6.5e-45 153.4 0.0 2.3e-44 151.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN98781.1 - 5.1e-41 140.8 0.0 7.6e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain GWT1 PF06423.12 RLN98781.1 - 0.029 14.5 3.1 0.064 13.4 3.1 1.6 1 0 0 1 1 1 0 GWT1 DUF3221 PF11518.8 RLN98784.1 - 1.8e-05 25.0 1.4 11 6.4 0.0 4.4 4 0 0 4 4 4 3 Protein of unknown function (DUF3221) UN_NPL4 PF11543.8 RLN98784.1 - 0.0033 17.9 0.0 44 4.6 0.0 3.4 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 PLDc_3 PF13918.6 RLN98784.1 - 0.048 13.3 0.0 49 3.5 0.0 3.2 3 0 0 3 3 3 0 PLD-like domain Ubiquitin_4 PF18036.1 RLN98784.1 - 0.082 13.0 0.0 34 4.6 0.0 3.0 3 0 0 3 3 3 0 Ubiquitin-like domain UPF0016 PF01169.19 RLN98784.1 - 0.17 12.2 1.3 58 4.1 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized protein family UPF0016 ORC_WH_C PF18137.1 RLN98784.1 - 0.33 11.0 3.5 2.6 8.1 3.5 2.1 1 1 0 1 1 1 0 Origin recognition complex winged helix C-terminal RabGAP-TBC PF00566.18 RLN98785.1 - 3.7e-37 128.1 0.4 5.3e-37 127.6 0.4 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain fn3 PF00041.21 RLN98785.1 - 1.2e-17 64.0 1.3 8.8e-11 42.0 0.1 3.2 3 0 0 3 3 3 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RLN98785.1 - 1.8e-06 28.4 7.5 0.0092 16.5 0.0 3.5 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain PDZ PF00595.24 RLN98785.1 - 1.3e-05 25.4 0.0 2.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RLN98785.1 - 0.00047 20.0 0.6 0.0013 18.5 0.2 2.0 2 0 0 2 2 2 1 PDZ domain Rhodanese PF00581.20 RLN98785.1 - 0.0029 18.1 0.0 2.4 8.7 0.0 2.6 2 0 0 2 2 2 2 Rhodanese-like domain PDZ_2 PF13180.6 RLN98785.1 - 0.0037 17.6 0.1 0.03 14.6 0.1 2.3 2 0 0 2 2 2 1 PDZ domain PhoD_N PF16655.5 RLN98785.1 - 0.027 15.0 0.1 12 6.5 0.0 3.1 2 1 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain PapD_C PF02753.17 RLN98785.1 - 8.5 6.8 8.3 11 6.5 0.2 3.6 4 0 0 4 4 4 0 Pili assembly chaperone PapD, C-terminal domain MORN PF02493.20 RLN98787.1 - 7.9e-87 280.3 112.6 8.8e-07 28.5 2.1 24.2 23 1 0 23 23 23 22 MORN repeat Avl9 PF09794.9 RLN98787.1 - 2e-11 43.3 0.0 6.3e-06 25.1 0.0 2.1 1 1 1 2 2 2 2 Transport protein Avl9 SPA PF08616.10 RLN98787.1 - 6.6e-07 29.3 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.21 RLN98787.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 DENN (AEX-3) domain PRO8NT PF08082.11 RLN98788.1 - 3.2e-05 23.9 2.0 4.2e-05 23.5 0.5 1.8 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain VirC2 PF07181.11 RLN98788.1 - 0.085 12.3 0.0 0.1 12.1 0.0 1.0 1 0 0 1 1 1 0 VirC2 protein Pkinase_Tyr PF07714.17 RLN98789.1 - 2.4e-51 174.5 0.0 3.4e-50 170.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN98789.1 - 3.2e-48 164.4 0.0 6e-48 163.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Thioredoxin PF00085.20 RLN98790.1 - 4.5e-51 171.1 0.4 9.4e-33 112.3 0.0 2.0 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 RLN98790.1 - 1.2e-12 48.2 0.7 1.2e-07 32.1 0.1 2.6 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 RLN98790.1 - 1.1e-10 41.3 0.1 8.8e-10 38.4 0.0 2.0 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 RLN98790.1 - 1.9e-07 31.0 0.1 0.00092 19.1 0.0 2.2 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 RLN98790.1 - 2.8e-07 30.6 0.0 0.0056 16.8 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 RLN98790.1 - 3.7e-07 30.4 0.1 0.0015 18.8 0.0 2.9 2 1 1 3 3 3 2 Thioredoxin-like TraF PF13728.6 RLN98790.1 - 3.4e-05 23.8 0.0 0.15 11.8 0.0 2.1 2 0 0 2 2 2 2 F plasmid transfer operon protein Redoxin PF08534.10 RLN98790.1 - 0.00023 20.9 0.2 0.084 12.6 0.1 2.2 2 0 0 2 2 2 2 Redoxin Thioredoxin_3 PF13192.6 RLN98790.1 - 0.016 15.2 0.1 0.41 10.7 0.0 2.4 2 1 0 2 2 2 0 Thioredoxin domain HyaE PF07449.11 RLN98790.1 - 0.073 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.6 RLN98790.1 - 0.18 12.0 0.9 7.8 6.6 0.2 2.3 2 0 0 2 2 2 0 Thioredoxin Glutaredoxin PF00462.24 RLN98790.1 - 0.31 11.3 1.9 29 5.0 0.1 2.7 2 1 0 2 2 2 0 Glutaredoxin LSM PF01423.22 RLN98792.1 - 6.1e-11 41.9 0.1 1.1e-10 41.1 0.1 1.3 1 0 0 1 1 1 1 LSM domain F-box_4 PF15966.5 RLN98792.1 - 0.0025 17.7 0.1 0.0049 16.7 0.1 1.5 1 0 0 1 1 1 1 F-box F-box PF00646.33 RLN98792.1 - 0.0032 17.3 0.3 0.0087 15.9 0.3 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 RLN98792.1 - 0.0037 17.1 3.1 0.0041 17.0 1.4 2.0 2 0 0 2 2 2 1 F-box-like Elongin_A PF06881.11 RLN98792.1 - 0.091 13.3 0.0 0.38 11.3 0.0 2.1 2 1 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A HSP70 PF00012.20 RLN98793.1 - 4.5e-16 58.2 10.1 1.5e-15 56.5 10.1 1.8 1 1 0 1 1 1 1 Hsp70 protein Pkinase PF00069.25 RLN98794.1 - 3e-70 236.6 0.0 4.2e-70 236.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN98794.1 - 2.5e-32 112.2 0.0 3.9e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RLN98794.1 - 0.0021 17.1 0.2 0.0032 16.5 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RLN98794.1 - 0.011 15.1 0.4 0.022 14.1 0.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SnoaL_2 PF12680.7 RLN98794.1 - 0.03 15.0 0.2 0.071 13.8 0.2 1.6 1 0 0 1 1 1 0 SnoaL-like domain PemK_toxin PF02452.17 RLN98795.1 - 0.46 10.9 0.1 0.46 10.9 0.1 2.8 2 1 0 2 2 2 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system AHH PF14412.6 RLN98795.1 - 2.2 8.4 8.2 0.81 9.8 4.3 2.3 1 1 1 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH MIT PF04212.18 RLN98797.1 - 2.8e-05 24.1 1.2 2.8e-05 24.1 1.2 1.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain NEMO PF11577.8 RLN98797.1 - 0.0023 17.9 4.1 1.4 9.0 2.3 2.4 2 0 0 2 2 2 2 NF-kappa-B essential modulator NEMO Macoilin PF09726.9 RLN98797.1 - 0.021 13.4 2.2 0.024 13.2 2.2 1.1 1 0 0 1 1 1 0 Macoilin family V_ATPase_I PF01496.19 RLN98797.1 - 0.33 8.8 4.1 0.4 8.5 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PGA2 PF07543.12 RLN98797.1 - 0.98 9.4 12.6 0.055 13.5 6.6 1.9 2 0 0 2 2 2 0 Protein trafficking PGA2 TMEM52 PF14979.6 RLN98797.1 - 1.5 8.8 4.3 5.4 6.9 0.3 2.5 1 1 1 2 2 2 0 Transmembrane 52 Folate_rec PF03024.14 RLN98798.1 - 1.9e-08 34.4 4.1 2.5e-08 34.0 4.1 1.2 1 0 0 1 1 1 1 Folate receptor family Fz PF01392.22 RLN98798.1 - 0.032 14.8 3.2 0.052 14.2 3.2 1.3 1 0 0 1 1 1 0 Fz domain MCR PF18509.1 RLN98798.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Magnetochrome domain CUE PF02845.16 RLN98799.1 - 4.7e-09 35.8 0.0 7.1e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 CUE domain VIR_N PF15912.5 RLN98799.1 - 0.12 12.0 1.5 0.2 11.2 1.5 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal DMA PF03474.14 RLN98799.1 - 0.16 11.6 0.0 0.39 10.3 0.0 1.7 1 1 0 1 1 1 0 DMRTA motif Herpes_UL49_2 PF04823.12 RLN98800.1 - 0.045 13.9 0.4 0.36 11.0 0.1 2.6 2 0 0 2 2 2 0 Herpesvirus UL49 tegument protein GYF PF02213.16 RLN98801.1 - 2.9e-10 39.6 0.5 7.8e-10 38.3 0.5 1.7 1 0 0 1 1 1 1 GYF domain CusF_Ec PF11604.8 RLN98801.1 - 0.045 13.7 0.0 0.16 12.0 0.0 1.9 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF Fcf1 PF04900.12 RLN98802.1 - 2.3e-38 130.6 2.7 2.3e-38 130.6 2.7 1.5 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 RLN98802.1 - 6.6e-11 42.5 0.0 1.1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 PIN like domain AD PF09793.9 RLN98803.1 - 6.8e-24 83.8 0.1 1.1e-23 83.2 0.1 1.3 1 0 0 1 1 1 1 Anticodon-binding domain Gemin6 PF06372.12 RLN98803.1 - 2.1e-08 33.9 0.1 0.00057 19.5 0.1 2.2 2 0 0 2 2 2 2 Gemin6 protein NDUF_B7 PF05676.13 RLN98804.1 - 2.8e-25 87.8 2.7 3.3e-25 87.6 2.7 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 RLN98804.1 - 6.1e-05 23.0 0.8 7e-05 22.8 0.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 RLN98804.1 - 0.032 14.5 2.0 0.07 13.4 2.0 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 TBP PF00352.21 RLN98805.1 - 8.7e-15 54.4 0.0 1e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 RLN98805.1 - 0.22 11.7 0.0 0.25 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3378) Y_Y_Y PF07495.13 RLN98806.1 - 0.0018 18.2 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 Y_Y_Y domain TcfC PF16967.5 RLN98806.1 - 0.13 11.8 0.3 0.25 10.8 0.0 1.6 2 0 0 2 2 2 0 E-set like domain Methyltransf_25 PF13649.6 RLN98807.1 - 3.8e-14 53.2 0.0 3.2e-13 50.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Trypsin_2 PF13365.6 RLN98807.1 - 8e-14 52.8 0.1 2.5e-13 51.2 0.1 1.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain Methyltransf_11 PF08241.12 RLN98807.1 - 1.1e-12 48.4 0.0 3.4e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 RLN98807.1 - 5.5e-11 42.3 0.0 2.4e-10 40.2 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 RLN98807.1 - 9.3e-09 35.9 0.0 2.7e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RLN98807.1 - 1.9e-08 34.2 0.0 4.9e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN98807.1 - 5.6e-07 29.5 0.0 1.4e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Peptidase_C3 PF00548.20 RLN98807.1 - 0.00067 19.6 0.1 0.0013 18.7 0.1 1.4 1 0 0 1 1 1 1 3C cysteine protease (picornain 3C) MTS PF05175.14 RLN98807.1 - 0.016 14.7 0.0 0.26 10.8 0.0 3.0 4 1 0 4 4 4 0 Methyltransferase small domain Trypsin PF00089.26 RLN98807.1 - 0.022 14.5 1.3 0.31 10.8 1.3 2.2 1 1 0 1 1 1 0 Trypsin PSD3 PF07626.11 RLN98807.1 - 0.058 13.9 0.2 25 5.5 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1587) Peptidase_C4 PF00863.19 RLN98807.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C4 DNA_pol_E_B PF04042.16 RLN98808.1 - 1.1e-07 31.4 0.1 0.0012 18.2 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 RLN98808.1 - 0.0031 17.5 0.1 0.0041 17.1 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal GST_C_3 PF14497.6 RLN98809.1 - 5.5e-18 65.0 0.2 8.6e-18 64.4 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RLN98809.1 - 5.8e-10 39.4 0.0 2.1e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RLN98809.1 - 1.3e-05 25.3 0.0 3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RLN98809.1 - 0.00063 20.1 0.0 0.0026 18.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN98809.1 - 0.016 15.5 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain IPTL-CTERM PF18203.1 RLN98809.1 - 0.3 11.1 2.6 0.62 10.0 2.6 1.5 1 0 0 1 1 1 0 IPTL-CTERM motif GST_C_3 PF14497.6 RLN98810.1 - 9.1e-22 77.1 0.1 2e-21 76.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RLN98810.1 - 6.8e-08 32.6 0.1 3.1e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RLN98810.1 - 1.7e-06 28.2 0.0 4.6e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN98810.1 - 0.0016 18.7 0.0 0.0038 17.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 RLN98810.1 - 0.0022 18.4 0.0 0.0042 17.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN98810.1 - 0.0024 17.9 0.1 0.015 15.3 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain IFP_35_N PF07334.13 RLN98811.1 - 3.1 7.9 9.0 0.31 11.1 0.2 3.2 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus GST_C_3 PF14497.6 RLN98812.1 - 8.8e-21 74.0 0.1 1.5e-20 73.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RLN98812.1 - 7.1e-10 39.1 0.0 2e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RLN98812.1 - 1.4e-05 25.2 0.1 2.7e-05 24.3 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RLN98812.1 - 0.0044 17.4 0.0 0.0073 16.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RLN98812.1 - 0.0067 16.7 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RLN98812.1 - 0.023 14.7 0.0 0.081 13.0 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 RLN98812.1 - 0.18 12.6 0.0 0.43 11.3 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain DRY_EERY PF09750.9 RLN98813.1 - 5.2e-12 46.2 0.2 5.2e-12 46.2 0.2 2.4 2 2 0 2 2 2 1 Alternative splicing regulator Surp PF01805.20 RLN98813.1 - 0.0026 17.7 0.0 0.0055 16.7 0.0 1.5 1 0 0 1 1 1 1 Surp module SR-25 PF10500.9 RLN98814.1 - 9.9e-07 28.6 51.9 9.9e-07 28.6 51.9 2.3 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein VASt PF16016.5 RLN98815.1 - 5e-32 111.4 0.0 7.8e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain DUF4845 PF16137.5 RLN98815.1 - 0.065 14.1 0.5 0.16 12.9 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4845) Miff PF05644.11 RLN98815.1 - 0.13 11.9 4.5 0.36 10.4 0.3 2.5 2 0 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff UN_NPL4 PF11543.8 RLN98817.1 - 1.3e-11 44.8 0.0 2.4e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 ubiquitin PF00240.23 RLN98817.1 - 0.00017 21.2 0.0 0.00037 20.2 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin family YukD PF08817.10 RLN98817.1 - 0.0073 17.0 0.0 0.012 16.3 0.0 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD RepB PF07506.11 RLN98818.1 - 0.0063 16.6 2.2 0.045 13.8 1.4 2.7 2 0 0 2 2 2 1 RepB plasmid partitioning protein GYD PF08734.11 RLN98818.1 - 0.026 14.5 0.2 0.34 10.9 0.0 2.5 2 0 0 2 2 2 0 GYD domain DUF1376 PF07120.11 RLN98818.1 - 0.077 13.3 0.4 8.6 6.8 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1376) Usp PF00582.26 RLN98818.1 - 2.4 8.7 5.5 5.9 7.4 0.0 3.0 3 0 0 3 3 3 0 Universal stress protein family DUF348 PF03990.14 RLN98819.1 - 0.022 14.5 0.3 0.067 13.0 0.3 1.8 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain PX PF00787.24 RLN98820.1 - 0.00041 20.3 0.0 0.0016 18.4 0.0 1.9 2 0 0 2 2 2 1 PX domain C2 PF00168.30 RLN98821.1 - 1.6e-40 137.6 0.0 2.3e-14 53.5 0.0 3.6 3 0 0 3 3 3 3 C2 domain EF-hand_7 PF13499.6 RLN98821.1 - 1.4e-24 86.4 11.8 8e-13 48.6 1.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 RLN98821.1 - 2.1e-22 76.9 13.1 5.9e-07 28.6 0.1 5.4 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 RLN98821.1 - 7.2e-19 66.1 9.9 5.8e-06 25.8 0.2 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 RLN98821.1 - 4.5e-16 58.4 15.1 1.9e-08 34.0 0.3 4.9 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 RLN98821.1 - 2.6e-14 52.0 8.2 0.0002 20.7 0.1 4.6 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 RLN98821.1 - 1.5e-06 28.4 0.7 0.0014 19.0 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 RLN98821.1 - 8.6e-06 26.0 0.0 0.05 13.9 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RLN98821.1 - 0.00089 19.2 1.6 3.1 7.8 0.1 3.4 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.10 RLN98821.1 - 0.15 12.2 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Ca2+ insensitive EF hand SCAB_CC PF16712.5 RLN98823.1 - 0.052 13.4 6.5 0.77 9.6 3.4 2.3 2 0 0 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein Peptidase_M30 PF10460.9 RLN98823.1 - 0.076 11.9 0.2 0.097 11.6 0.2 1.1 1 0 0 1 1 1 0 Peptidase M30 DUF3523 PF12037.8 RLN98824.1 - 5.8e-97 324.2 28.2 7.8e-97 323.8 28.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 RLN98824.1 - 1.3e-22 80.6 0.0 3.7e-22 79.1 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RLN98824.1 - 1.2e-05 25.7 4.8 0.00036 21.0 0.2 3.7 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 RLN98824.1 - 3e-05 23.8 0.3 0.00033 20.4 0.0 2.7 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RLN98824.1 - 0.00082 19.4 0.9 0.013 15.5 0.1 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 RLN98824.1 - 0.0022 18.2 0.0 0.0022 18.2 0.0 2.6 2 2 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 RLN98824.1 - 0.0046 16.4 0.1 0.015 14.7 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 RLN98824.1 - 0.0053 17.0 9.4 0.017 15.4 0.0 3.5 3 2 0 4 4 4 1 AAA domain AAA_3 PF07726.11 RLN98824.1 - 0.0074 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 RLN98824.1 - 0.019 15.0 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 RLN98824.1 - 0.028 15.0 0.0 0.028 15.0 0.0 2.8 2 2 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 RLN98824.1 - 0.028 14.2 0.0 0.082 12.6 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 RLN98824.1 - 0.03 14.7 0.1 0.14 12.5 0.0 2.2 2 0 0 2 2 2 0 RNA helicase YhzD PF14120.6 RLN98824.1 - 0.041 14.0 0.7 2.6 8.2 0.0 3.2 3 0 0 3 3 2 0 YhzD-like protein AAA_lid_3 PF17862.1 RLN98824.1 - 0.044 13.6 0.8 0.17 11.7 0.1 2.3 2 0 0 2 2 2 0 AAA+ lid domain AAA_11 PF13086.6 RLN98824.1 - 0.2 11.4 0.0 0.2 11.4 0.0 3.0 2 1 0 2 2 1 0 AAA domain ADP_ribosyl_GH PF03747.14 RLN98825.1 - 2.8e-48 165.1 6.4 3.4e-48 164.9 6.4 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Lon_C PF05362.13 RLN98826.1 - 1.1e-53 181.8 1.7 3e-51 173.9 1.7 3.3 1 1 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 RLN98826.1 - 1.2e-29 103.7 0.0 3.2e-29 102.3 0.0 1.7 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 RLN98826.1 - 8.1e-21 74.8 0.0 2.8e-20 73.1 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RLN98826.1 - 3.8e-11 43.2 0.0 1.5e-10 41.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 RLN98826.1 - 9.7e-06 25.4 0.0 2.7e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 RLN98826.1 - 7.9e-05 21.7 0.0 0.00013 21.0 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 RLN98826.1 - 0.00022 21.5 1.3 0.079 13.2 0.1 3.5 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 RLN98826.1 - 0.001 18.8 0.0 0.0035 17.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 RLN98826.1 - 0.0017 18.8 3.6 0.0038 17.6 0.0 3.2 2 2 1 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 RLN98826.1 - 0.0036 17.2 0.1 0.0092 15.9 0.0 1.7 2 0 0 2 2 1 1 RsgA GTPase AAA_2 PF07724.14 RLN98826.1 - 0.0059 16.7 0.0 0.019 15.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 RLN98826.1 - 0.0059 16.4 0.2 0.058 13.1 0.0 2.5 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_18 PF13238.6 RLN98826.1 - 0.014 15.9 0.0 0.043 14.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 RLN98826.1 - 0.023 14.5 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 RLN98826.1 - 0.21 11.7 2.1 0.81 9.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain Hydrolase_6 PF13344.6 RLN98828.1 - 6.2e-11 42.3 0.0 1.1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RLN98828.1 - 7.3e-11 42.0 0.0 1.5e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 RLN98828.1 - 0.00011 22.4 0.1 0.00038 20.6 0.0 1.9 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RLN98828.1 - 0.00088 19.6 0.0 0.0035 17.7 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-C3HC4_3 PF13920.6 RLN98829.1 - 7.4e-13 48.1 5.6 1.2e-12 47.5 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) K-box PF01486.17 RLN98829.1 - 0.00074 19.6 2.4 0.00074 19.6 2.4 2.0 2 0 0 2 2 2 1 K-box region Prok-RING_4 PF14447.6 RLN98829.1 - 0.0012 18.7 5.9 0.0023 17.8 5.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RLN98829.1 - 0.024 14.6 4.9 0.044 13.8 4.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 RLN98829.1 - 0.14 12.5 6.2 0.27 11.6 6.2 1.5 1 0 0 1 1 1 0 Ring finger domain Abhydrolase_1 PF00561.20 RLN98830.1 - 7.1e-10 39.0 0.4 2.2e-05 24.2 0.0 4.1 3 1 1 4 4 4 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RLN98830.1 - 1e-09 38.0 0.1 1.8e-07 30.7 0.0 3.2 3 1 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RLN98830.1 - 1.5e-06 29.0 15.3 0.00012 22.8 0.6 2.9 3 0 0 3 3 3 2 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 RLN98830.1 - 0.0013 18.6 0.0 0.062 13.1 0.0 2.3 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_2 PF02230.16 RLN98830.1 - 0.01 15.7 0.1 5 6.9 0.0 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF3530 PF12048.8 RLN98830.1 - 0.021 14.2 0.1 4.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) LIDHydrolase PF10230.9 RLN98830.1 - 0.03 13.9 0.0 0.8 9.2 0.1 2.6 3 0 0 3 3 3 0 Lipid-droplet associated hydrolase Ndr PF03096.14 RLN98830.1 - 0.099 11.3 0.0 0.28 9.9 0.0 1.7 2 0 0 2 2 2 0 Ndr family V-ATPase_C PF03223.15 RLN98831.1 - 9.8e-84 281.9 0.0 1.2e-83 281.6 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Mst1_SARAH PF11629.8 RLN98831.1 - 0.28 11.3 0.8 0.67 10.1 0.8 1.6 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 AP3D1 PF06375.11 RLN98832.1 - 0.0027 18.0 17.4 0.0027 18.0 17.4 1.4 1 1 0 1 1 1 1 AP-3 complex subunit delta-1 BRF1 PF07741.13 RLN98832.1 - 0.0087 16.4 9.7 0.014 15.7 9.7 1.3 1 0 0 1 1 1 1 Brf1-like TBP-binding domain TRAP_alpha PF03896.16 RLN98832.1 - 0.11 11.7 1.2 0.13 11.5 1.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4692 PF15763.5 RLN98832.1 - 0.13 12.8 5.1 0.15 12.5 5.1 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) TFIIF_alpha PF05793.12 RLN98832.1 - 0.16 10.5 20.2 0.19 10.3 20.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Rtf2 PF04641.12 RLN98832.1 - 0.3 10.4 12.0 0.35 10.2 12.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger RNA_pol_Rpc4 PF05132.14 RLN98832.1 - 0.33 11.4 4.9 0.4 11.1 4.9 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 RLN98832.1 - 0.34 10.7 7.6 0.38 10.6 7.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sporozoite_P67 PF05642.11 RLN98832.1 - 0.35 8.9 6.1 0.39 8.8 6.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM60A PF15396.6 RLN98832.1 - 0.56 10.2 12.0 0.65 10.0 12.0 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 RLN98832.1 - 0.6 8.8 8.9 0.74 8.5 8.9 1.0 1 0 0 1 1 1 0 Presenilin MCM_bind PF09739.9 RLN98832.1 - 0.6 8.5 7.3 0.68 8.3 7.3 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor CPSF100_C PF13299.6 RLN98832.1 - 0.64 10.2 7.4 0.81 9.9 7.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FAM104 PF15434.6 RLN98832.1 - 0.65 10.6 11.9 1.1 9.9 11.9 1.5 1 0 0 1 1 1 0 Family 104 LRIF1 PF15741.5 RLN98832.1 - 0.84 8.1 11.5 0.89 8.0 11.5 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 CDC45 PF02724.14 RLN98832.1 - 0.9 7.7 13.8 1 7.6 13.8 1.0 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 RLN98832.1 - 1.1 8.0 6.9 1.2 7.9 6.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter P_C PF06640.11 RLN98832.1 - 1.2 9.2 10.9 1.5 8.9 10.9 1.1 1 0 0 1 1 1 0 P protein C-terminus Peroxin-3 PF04882.12 RLN98832.1 - 2.9 6.8 11.8 3.7 6.4 11.8 1.0 1 0 0 1 1 1 0 Peroxin-3 Zip PF02535.22 RLN98832.1 - 3.4 6.8 6.5 3.9 6.6 6.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3464 PF11947.8 RLN98832.1 - 5.6 6.7 10.4 7.2 6.4 10.4 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4228 PF14009.6 RLN98832.1 - 6 7.2 11.0 7 7.0 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Suf PF05843.14 RLN98833.1 - 1.6e-43 149.8 1.5 4.2e-40 138.6 0.0 3.7 4 1 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 RLN98833.1 - 0.0003 21.3 0.5 0.0003 21.3 0.5 6.0 6 2 2 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 RLN98833.1 - 0.00057 20.3 4.5 0.19 12.2 0.3 4.2 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN98833.1 - 0.00077 19.4 3.4 0.38 11.0 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN98833.1 - 0.015 15.4 0.2 0.32 11.3 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 RLN98833.1 - 0.02 15.5 2.8 12 6.8 0.0 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 RLN98833.1 - 0.05 14.0 0.2 9.2 6.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 RLN98833.1 - 0.088 13.5 0.6 0.088 13.5 0.6 3.7 4 1 1 5 5 5 0 Tetratricopeptide repeat OTCace_N PF02729.21 RLN98835.1 - 1.4e-38 132.2 0.0 4.4e-38 130.6 0.0 1.8 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 RLN98835.1 - 6.6e-37 127.0 0.1 8.5e-37 126.6 0.1 1.1 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain CENP-B_N PF04218.13 RLN98836.1 - 1.1e-05 25.0 0.8 1.8e-05 24.3 0.8 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_32 PF13565.6 RLN98836.1 - 0.00058 20.4 0.0 0.00098 19.7 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.12 RLN98836.1 - 0.0066 16.4 0.2 0.013 15.5 0.2 1.5 1 0 0 1 1 1 1 HTH domain HTH_23 PF13384.6 RLN98836.1 - 0.011 15.5 0.1 0.019 14.8 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_24 PF13412.6 RLN98836.1 - 0.014 14.9 0.1 0.024 14.2 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 RLN98836.1 - 0.022 14.8 0.2 0.036 14.1 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix GntR PF00392.21 RLN98836.1 - 0.032 13.9 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_DeoR PF08220.12 RLN98836.1 - 0.049 13.4 0.2 0.31 10.8 0.0 2.2 2 1 1 3 3 3 0 DeoR-like helix-turn-helix domain HTH_AsnC-type PF13404.6 RLN98836.1 - 0.092 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_psq PF05225.16 RLN98836.1 - 0.1 12.3 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain DEAD PF00270.29 RLN98837.1 - 2e-43 148.2 0.0 2.4e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 RLN98837.1 - 9.3e-08 32.3 0.0 1.1e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit OMPdecase PF00215.24 RLN98837.1 - 0.023 14.3 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family UvrD-helicase PF00580.21 RLN98837.1 - 0.15 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain zf-C3HC4 PF00097.25 RLN98838.1 - 3.2e-08 33.3 9.9 3.2e-08 33.3 9.9 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RLN98838.1 - 2e-07 30.9 9.4 2.5e-07 30.6 7.7 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 RLN98838.1 - 3.2e-07 30.6 11.0 3.2e-07 30.6 11.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 RLN98838.1 - 3.1e-06 26.9 7.1 3.1e-06 26.9 7.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RLN98838.1 - 3.9e-06 26.6 12.8 3.9e-06 26.6 12.8 2.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RLN98838.1 - 1.7e-05 25.0 5.9 6.1e-05 23.2 5.9 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RLN98838.1 - 2e-05 24.4 8.4 2e-05 24.4 8.4 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 RLN98838.1 - 4.2e-05 23.6 12.4 4.2e-05 23.6 12.4 2.2 3 0 0 3 3 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RLN98838.1 - 0.00051 19.9 9.2 0.031 14.1 9.8 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 RLN98838.1 - 0.0018 18.3 2.3 0.004 17.2 2.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PWI PF01480.17 RLN98838.1 - 0.0037 17.6 0.0 0.0076 16.5 0.0 1.5 1 0 0 1 1 1 1 PWI domain zf-RING_6 PF14835.6 RLN98838.1 - 0.0082 16.0 5.0 0.031 14.1 5.0 2.0 1 1 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 RLN98838.1 - 0.036 13.9 6.4 0.15 11.9 6.2 2.0 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 RLN98838.1 - 0.2 11.4 10.2 0.64 9.8 10.2 1.9 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Zn-C2H2_12 PF18112.1 RLN98838.1 - 0.24 11.9 0.1 0.24 11.9 0.1 2.8 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain GAGA PF09237.11 RLN98838.1 - 0.33 10.8 0.0 0.33 10.8 0.0 2.9 3 0 0 3 3 3 0 GAGA factor Mannosyl_trans3 PF11051.8 RLN98840.1 - 8.2e-33 113.9 0.0 2.3e-31 109.2 0.0 2.2 1 1 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.8 RLN98841.1 - 8.4e-36 123.7 0.0 6.6e-35 120.8 0.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative Glyco_tranf_2_3 PF13641.6 RLN98841.1 - 0.043 13.7 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Mannosyl_trans3 PF11051.8 RLN98842.1 - 6.2e-32 111.1 0.0 1.5e-30 106.5 0.0 2.1 1 1 0 1 1 1 1 Mannosyltransferase putative ABC2_membrane PF01061.24 RLN98843.1 - 1.8e-37 128.8 26.9 1.8e-37 128.8 26.9 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RLN98843.1 - 2e-16 60.8 0.0 3e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RLN98843.1 - 1.7e-05 24.8 0.0 0.032 14.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system PDR_assoc PF08370.11 RLN98843.1 - 0.0052 16.5 0.9 0.0052 16.5 0.9 2.6 2 0 0 2 2 2 1 Plant PDR ABC transporter associated AAA_29 PF13555.6 RLN98843.1 - 0.0097 15.6 0.6 0.02 14.6 0.6 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RLN98843.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 RLN98843.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 RLN98843.1 - 0.023 15.2 0.0 0.036 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RLN98843.1 - 0.099 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 RLN98843.1 - 0.11 12.0 0.2 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 RLN98843.1 - 0.22 11.0 0.1 2.6 7.4 0.1 2.3 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain TsaE PF02367.17 RLN98843.1 - 0.22 11.5 0.2 0.44 10.5 0.2 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC2_membrane_3 PF12698.7 RLN98843.1 - 0.25 10.4 30.1 3.9 6.5 30.1 2.1 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF87 PF01935.17 RLN98843.1 - 0.54 10.3 1.6 0.97 9.5 1.6 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain PDR_CDR PF06422.12 RLN98843.1 - 3.2 7.7 7.2 10 6.1 1.8 3.1 2 1 0 3 3 3 0 CDR ABC transporter RNA_ligase PF09414.10 RLN98844.1 - 1.6e-23 83.8 0.0 2.5e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 RNA ligase AAA_33 PF13671.6 RLN98844.1 - 3.2e-10 40.3 0.1 7.3e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain PTPlike_phytase PF14566.6 RLN98844.1 - 8.7e-06 25.9 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 RLN98844.1 - 0.0021 18.1 0.0 0.0043 17.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 RLN98844.1 - 0.0025 17.4 0.0 0.0056 16.3 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase AAA_16 PF13191.6 RLN98844.1 - 0.0033 17.8 0.3 0.011 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain DSPc PF00782.20 RLN98844.1 - 0.0035 17.2 0.0 0.007 16.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain AAA_18 PF13238.6 RLN98844.1 - 0.006 17.1 0.0 0.018 15.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain Y_phosphatase2 PF03162.13 RLN98844.1 - 0.012 15.2 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family LigT_PEase PF02834.16 RLN98844.1 - 0.031 14.5 0.0 0.08 13.1 0.0 1.6 1 0 0 1 1 1 0 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 RLN98844.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.9 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily AAA_22 PF13401.6 RLN98844.1 - 0.11 12.8 0.0 0.4 11.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 RLN98844.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CBS PF00571.28 RLN98845.1 - 8.4e-09 35.8 0.4 2.3e-08 34.3 0.1 1.9 2 0 0 2 2 2 1 CBS domain I_LWEQ PF01608.17 RLN98845.1 - 0.0044 17.3 6.1 0.0083 16.4 6.1 1.4 1 0 0 1 1 1 1 I/LWEQ domain GARS_N PF02844.15 RLN98845.1 - 0.044 14.6 0.3 0.49 11.2 0.1 2.2 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain Ald_Xan_dh_C2 PF02738.18 RLN98845.1 - 0.069 11.6 4.8 0.082 11.4 4.8 1.1 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase Pkinase PF00069.25 RLN98846.1 - 3.6e-06 26.5 0.0 4e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PDZ PF00595.24 RLN98848.1 - 7e-08 32.7 0.0 2e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RLN98848.1 - 4.6e-07 29.6 0.0 1.2e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RLN98848.1 - 1.3e-06 28.6 0.1 8.2e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 PDZ domain VPS13_C PF16909.5 RLN98848.1 - 6.5e-06 26.0 0.0 1.8e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal Tricorn_PDZ PF14685.6 RLN98848.1 - 0.0058 16.6 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 Tricorn protease PDZ domain SHR-BD PF06650.12 RLN98848.1 - 0.0098 15.3 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 DUF656 PF04920.12 RLN98849.1 - 0.011 15.7 0.1 0.026 14.5 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF656) FYVE_2 PF02318.16 RLN98849.1 - 0.019 15.1 5.0 0.033 14.4 5.0 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger DHC PF09626.10 RLN98849.1 - 0.02 15.8 1.2 0.033 15.1 0.2 1.8 2 0 0 2 2 2 0 Dihaem cytochrome c DUF4780 PF16012.5 RLN98849.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4780) zf-RING_4 PF14570.6 RLN98849.1 - 0.17 11.7 4.2 0.36 10.6 1.4 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain C1_1 PF00130.22 RLN98849.1 - 1.3 9.0 8.8 1.2 9.1 6.9 1.9 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_3 PF13920.6 RLN98849.1 - 4.5 7.2 10.6 0.2 11.6 3.7 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF92 PF01940.16 RLN98850.1 - 2.3e-19 69.8 1.6 2.6e-19 69.6 1.6 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 Penicillinase_R PF03965.16 RLN98851.1 - 0.031 14.6 1.6 1.7 9.0 0.2 2.6 2 0 0 2 2 2 0 Penicillinase repressor Na_trans_assoc PF06512.13 RLN98851.1 - 0.44 10.8 0.0 0.44 10.8 0.0 2.2 2 1 0 2 2 2 0 Sodium ion transport-associated AA_permease_2 PF13520.6 RLN98852.1 - 2.4e-27 95.8 31.6 3.5e-27 95.3 31.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN98852.1 - 1.7e-15 56.6 29.9 2.2e-15 56.2 29.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1461 PF07314.11 RLN98852.1 - 2.1 8.2 8.7 0.69 9.8 0.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1461) FYVE_2 PF02318.16 RLN98853.1 - 0.68 10.2 9.4 1.5 9.1 9.4 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4_3 PF13920.6 RLN98853.1 - 0.96 9.4 19.8 0.49 10.3 11.1 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 RLN98854.1 - 0.029 14.6 1.8 0.069 13.4 1.8 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 RLN98854.1 - 0.06 13.5 3.8 0.13 12.4 3.8 1.6 1 0 0 1 1 1 0 FYVE zinc finger Snurportin1 PF11538.8 RLN98854.1 - 0.21 11.8 3.6 0.13 12.4 0.9 2.1 2 0 0 2 2 2 0 Snurportin1 OrfB_Zn_ribbon PF07282.11 RLN98855.1 - 8.1e-10 38.5 0.2 1.6e-09 37.5 0.2 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain APC_u15 PF16636.5 RLN98855.1 - 0.0057 17.1 2.8 0.0074 16.7 2.8 1.2 1 0 0 1 1 1 1 Unstructured region on APC between APC_crr regions 5 and 6 SprA-related PF12118.8 RLN98855.1 - 0.093 11.9 2.8 0.12 11.6 2.8 1.1 1 0 0 1 1 1 0 SprA-related family LRR_6 PF13516.6 RLN98856.1 - 2.1e-11 42.9 7.0 0.0076 16.2 0.1 6.6 7 0 0 7 7 6 2 Leucine Rich repeat LRR_1 PF00560.33 RLN98856.1 - 7.5e-05 22.8 7.1 16 6.5 0.1 6.3 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 RLN98856.1 - 0.00047 20.5 9.0 2.4 8.7 0.1 5.1 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RLN98856.1 - 0.0052 16.5 11.0 0.75 9.6 1.2 4.7 5 2 1 6 6 6 3 Leucine rich repeat CLZ PF16526.5 RLN98856.1 - 0.037 14.4 2.7 9.5 6.7 0.5 3.7 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 RLN98856.1 - 0.05 13.6 3.8 0.82 9.7 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) UPF0270 PF06794.12 RLN98856.1 - 0.24 11.5 2.2 0.78 9.9 0.5 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) ABC_tran_CTD PF16326.5 RLN98856.1 - 0.56 10.5 8.7 9.3 6.6 0.5 3.7 2 1 2 4 4 4 0 ABC transporter C-terminal domain UPAR_LY6 PF00021.21 RLN98856.1 - 0.78 10.5 3.3 0.7 10.6 0.7 2.2 2 0 0 2 2 2 0 u-PAR/Ly-6 domain PriC PF07445.12 RLN98856.1 - 1.6 8.6 11.0 0.43 10.5 0.4 2.8 2 1 0 2 2 2 0 Primosomal replication protein priC Cortex-I_coil PF09304.10 RLN98856.1 - 3.4 7.9 6.8 5 7.4 0.3 3.4 2 1 0 2 2 2 0 Cortexillin I, coiled coil Lant_dehydr_C PF14028.6 RLN98856.1 - 4.8 6.6 11.9 2.9 7.3 6.6 3.1 3 1 0 3 3 3 0 Lantibiotic biosynthesis dehydratase C-term Fez1 PF06818.15 RLN98856.1 - 5 7.5 10.4 44 4.4 10.4 2.1 1 1 0 1 1 1 0 Fez1 ADIP PF11559.8 RLN98856.1 - 6.1 6.9 9.1 3.8 7.6 2.5 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4164 PF13747.6 RLN98856.1 - 7.6 6.9 14.5 2.3 8.6 2.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) bZIP_2 PF07716.15 RLN98857.1 - 0.0027 17.7 9.6 0.0027 17.7 9.6 2.9 3 0 0 3 3 3 1 Basic region leucine zipper HHH_3 PF12836.7 RLN98857.1 - 0.044 14.0 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif bZIP_2 PF07716.15 RLN98858.1 - 6.8 6.9 15.8 2.3 8.4 8.8 2.6 2 0 0 2 2 2 0 Basic region leucine zipper SWIRM PF04433.17 RLN98859.1 - 2.5e-29 101.4 0.0 5.8e-29 100.3 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 RLN98859.1 - 4.4e-16 58.6 7.3 4.4e-16 58.6 7.3 2.2 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 RLN98859.1 - 4.5e-05 23.5 0.0 9.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RLN98859.1 - 0.023 15.0 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 RLN98859.1 - 0.18 12.2 0.1 0.39 11.1 0.1 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain FOXP-CC PF16159.5 RLN98859.1 - 2.2 9.0 4.1 5.1 7.8 4.1 1.6 1 0 0 1 1 1 0 FOXP coiled-coil domain DUF4833 PF16117.5 RLN98860.1 - 1.8e-41 141.3 0.0 2.2e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4833) CDC45 PF02724.14 RLN98861.1 - 8.5e-177 589.3 0.1 1e-176 589.0 0.1 1.0 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 RLN98861.1 - 2.7 7.3 20.5 5.9 6.2 20.5 1.5 1 0 0 1 1 1 0 SDA1 DUF4750 PF15938.5 RLN98862.1 - 7e-21 73.6 1.6 1.1e-20 73.1 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4750) SUZ PF12752.7 RLN98862.1 - 0.076 13.8 0.0 0.13 13.0 0.0 1.4 1 0 0 1 1 1 0 SUZ domain QCR10 PF09796.9 RLN98862.1 - 0.098 12.7 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) CrgA PF06781.12 RLN98862.1 - 0.19 11.8 1.7 0.8 9.8 0.9 2.0 1 1 1 2 2 2 0 Cell division protein CrgA PCMT PF01135.19 RLN98863.1 - 6.8e-102 339.6 0.0 1.9e-50 171.5 0.0 2.1 1 1 1 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 RLN98863.1 - 9.7e-13 48.7 0.3 6.1e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_32 PF13679.6 RLN98863.1 - 4.5e-11 43.0 0.0 0.00013 22.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 RLN98863.1 - 1.5e-10 41.1 0.0 0.00014 21.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 RLN98863.1 - 1.2e-09 38.7 0.1 0.0023 18.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 RLN98863.1 - 8.8e-07 28.9 0.0 0.015 15.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 RLN98863.1 - 4.3e-06 26.4 0.0 0.046 13.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase small domain RrnaAD PF00398.20 RLN98863.1 - 1.5e-05 24.2 0.0 0.039 13.0 0.0 2.3 2 0 0 2 2 2 2 Ribosomal RNA adenine dimethylase GCD14 PF08704.10 RLN98863.1 - 7e-05 22.6 0.0 0.15 11.7 0.0 2.1 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.13 RLN98863.1 - 0.00096 18.6 0.7 0.43 9.9 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 RLN98863.1 - 0.001 19.8 0.2 2.7 8.8 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain DREV PF05219.12 RLN98863.1 - 0.002 17.3 0.0 0.87 8.6 0.0 2.2 2 0 0 2 2 2 2 DREV methyltransferase Methyltransf_9 PF08003.11 RLN98863.1 - 0.0026 16.7 0.1 2.6 6.9 0.0 2.9 2 2 0 2 2 2 2 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 RLN98863.1 - 0.0096 15.3 0.0 2 7.7 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family AviRa PF11599.8 RLN98863.1 - 0.029 13.8 0.0 0.76 9.2 0.0 2.1 2 0 0 2 2 2 0 RRNA methyltransferase AviRa MetW PF07021.12 RLN98863.1 - 0.2 11.2 0.1 10 5.6 0.1 2.2 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Pkinase_Tyr PF07714.17 RLN98864.1 - 1e-26 93.8 0.0 6.4e-20 71.5 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 RLN98864.1 - 4.2e-24 85.3 0.0 8.2e-22 77.8 0.0 3.4 1 1 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 RLN98864.1 - 2.9e-14 52.6 1.1 3.9e-05 23.3 0.3 3.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_5 PF13306.6 RLN98864.1 - 2.8e-05 24.1 0.0 5.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 RLN98864.1 - 0.0091 16.4 3.3 0.26 11.8 0.0 3.5 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) Kinase-like PF14531.6 RLN98864.1 - 0.041 13.2 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Ephrin_rec_like PF07699.13 RLN98864.1 - 0.054 13.3 5.2 0.52 10.1 4.6 2.5 1 1 0 1 1 1 0 Putative ephrin-receptor like TNFR_c6 PF00020.18 RLN98864.1 - 0.34 11.3 3.2 0.2 12.1 0.8 1.9 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region WD40 PF00400.32 RLN98865.1 - 8.2e-24 83.4 15.7 3.1e-05 24.6 0.1 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RLN98865.1 - 6.7e-08 32.7 1.9 0.0024 18.1 0.7 2.8 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RLN98865.1 - 0.0093 14.7 3.7 0.089 11.4 0.4 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PAS_4 PF08448.10 RLN98866.1 - 0.067 13.5 1.1 0.58 10.4 0.1 2.3 1 1 1 2 2 2 0 PAS fold LisH_TPL PF17814.1 RLN98867.1 - 0.16 11.6 1.9 0.49 10.1 0.9 2.2 2 0 0 2 2 2 0 LisH-like dimerisation domain SBE2 PF17076.5 RLN98867.1 - 2 6.5 5.2 2.8 6.0 5.2 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation Osmo_CC PF08946.10 RLN98870.1 - 0.0078 16.4 0.2 0.0078 16.4 0.2 3.0 3 1 1 4 4 4 1 Osmosensory transporter coiled coil DUF987 PF06174.11 RLN98870.1 - 0.19 11.7 0.0 0.42 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF987) TMP_2 PF06791.13 RLN98870.1 - 0.75 9.4 7.2 1.3 8.7 1.5 2.3 2 0 0 2 2 2 0 Prophage tail length tape measure protein Pkinase_Tyr PF07714.17 RLN98872.1 - 6.2e-55 186.3 0.0 8e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN98872.1 - 7.1e-47 160.0 0.0 1e-46 159.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Cu_amine_oxid PF01179.20 RLN98874.1 - 1.5e-149 498.4 0.0 1.8e-149 498.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 RLN98874.1 - 2.6e-15 56.6 0.0 5.2e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 RLN98874.1 - 0.0002 21.5 0.0 0.0004 20.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Ribosomal_S4e PF00900.20 RLN98874.1 - 0.2 11.6 0.0 0.5 10.3 0.0 1.6 1 0 0 1 1 1 0 Ribosomal family S4e AA_permease_2 PF13520.6 RLN98875.1 - 1.5e-42 145.9 38.5 2e-42 145.6 38.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN98875.1 - 3.5e-28 98.5 34.8 5.7e-28 97.7 34.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 RLN98876.1 - 1.4e-39 136.1 40.1 1.9e-39 135.7 40.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RLN98876.1 - 4.8e-27 94.7 38.6 6.7e-27 94.2 38.6 1.2 1 0 0 1 1 1 1 Amino acid permease Aldedh PF00171.22 RLN98877.1 - 0 1143.0 1.4 3.4e-173 576.4 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family RNA_pol_Rpb2_45 PF10385.9 RLN98877.1 - 0.011 15.9 0.0 8.5 6.7 0.0 2.8 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain HetR_C PF18460.1 RLN98877.1 - 0.1 12.6 0.2 25 4.9 0.0 2.5 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain Elicitin PF00964.17 RLN98879.1 - 0.0005 20.1 1.2 0.00095 19.2 1.2 1.5 1 1 0 1 1 1 1 Elicitin SWC7 PF17330.2 RLN98879.1 - 0.2 11.7 0.0 8.3 6.5 0.0 2.6 3 0 0 3 3 3 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 Pkinase PF00069.25 RLN98880.1 - 6.5e-51 173.2 0.0 9.1e-51 172.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN98880.1 - 2.7e-45 154.7 0.0 3.9e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RLN98880.1 - 0.059 12.7 0.1 0.088 12.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RLN98880.1 - 0.087 11.7 0.0 0.26 10.2 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 RLN98881.1 - 5.1e-21 75.2 0.0 6e-21 75.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RLN98881.1 - 2.6e-16 59.7 0.0 2.9e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 RLN98882.1 - 6e-143 465.8 52.3 5e-14 52.7 0.3 11.2 1 1 10 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN98882.1 - 2e-125 407.7 32.6 4.9e-11 42.9 0.1 14.2 5 4 10 16 16 16 16 Ankyrin repeats (many copies) Ank PF00023.30 RLN98882.1 - 3.9e-97 314.8 62.2 7.1e-05 23.1 0.0 22.2 22 0 0 22 22 22 20 Ankyrin repeat Ank_5 PF13857.6 RLN98882.1 - 4.5e-93 304.1 46.4 3.7e-07 30.3 0.0 21.3 1 1 21 22 22 22 22 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN98882.1 - 1.7e-89 282.9 19.3 0.019 15.5 0.0 22.3 22 0 0 22 22 22 21 Ankyrin repeat DUF1949 PF09186.11 RLN98882.1 - 9.9e-09 34.9 4.0 7.6 6.5 0.0 10.4 11 0 0 11 11 11 1 Domain of unknown function (DUF1949) DUF4926 PF16277.5 RLN98882.1 - 0.00012 21.4 0.0 78 2.7 0.1 8.1 9 0 0 9 9 9 0 Domain of unknown function (DUF4926) PsaM PF07465.13 RLN98882.1 - 0.0076 15.9 7.5 3.3e+02 1.1 0.0 9.4 11 0 0 11 11 11 0 Photosystem I protein M (PsaM) PK_C PF02887.16 RLN98882.1 - 0.0085 16.3 23.9 40 4.5 0.0 10.0 9 2 1 11 11 11 0 Pyruvate kinase, alpha/beta domain Aa_trans PF01490.18 RLN98883.1 - 2.3e-37 128.7 19.3 2.8e-37 128.4 19.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RPN2_C PF18004.1 RLN98884.1 - 1.1e-37 129.4 6.9 1.5e-37 129.0 6.9 1.1 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 RLN98884.1 - 0.016 15.6 0.2 0.046 14.2 0.2 1.8 1 0 0 1 1 1 0 Proteasome/cyclosome repeat GAPT PF11770.8 RLN98884.1 - 0.032 14.1 0.7 0.051 13.4 0.7 1.2 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Vfa1 PF08432.10 RLN98884.1 - 2.2 8.6 8.0 3 8.1 8.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 MFS_MOT1 PF16983.5 RLN98885.1 - 4.5e-52 175.1 29.3 5.2e-28 97.7 7.8 2.7 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Xan_ur_permease PF00860.20 RLN98885.1 - 0.00044 19.1 31.3 0.0041 15.9 10.4 3.1 2 1 1 3 3 3 3 Permease family CHD5 PF04420.14 RLN98885.1 - 0.053 13.4 0.3 0.15 11.9 0.3 1.7 1 0 0 1 1 1 0 CHD5-like protein Sec1 PF00995.23 RLN98886.1 - 4.3e-123 412.6 0.0 4.9e-123 412.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF4833 PF16117.5 RLN98887.1 - 7.4e-41 139.4 0.0 9.1e-41 139.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4833) DcpS_C PF11969.8 RLN98888.1 - 3.3e-14 53.3 6.1 2e-13 50.8 6.1 1.9 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 RLN98888.1 - 2.6e-09 37.7 5.2 7.6e-09 36.2 5.2 1.7 1 1 0 1 1 1 1 HIT domain Sugar_tr PF00083.24 RLN98889.1 - 3.3e-35 121.8 15.8 1.9e-24 86.3 0.6 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RLN98889.1 - 1e-08 34.5 36.6 3.4e-08 32.8 31.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Tail_VII PF17091.5 RLN98889.1 - 4.1 7.4 9.0 0.8 9.6 0.1 3.7 3 0 0 3 3 3 0 Inovirus G7P protein DNA_pol_A_exo1 PF01612.20 RLN98890.1 - 6e-40 136.8 0.8 1e-39 136.1 0.8 1.4 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 RLN98890.1 - 8.1e-12 45.0 0.0 2e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.12 RLN98890.1 - 6.8e-06 26.7 1.6 2.6e-05 24.8 0.4 2.7 2 0 0 2 2 2 1 PMC2NT (NUC016) domain DUF641 PF04859.12 RLN98890.1 - 0.033 14.5 1.3 1.2 9.5 0.1 2.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Trypan_PARP PF05887.11 RLN98891.1 - 0.0057 16.6 3.9 0.01 15.8 3.9 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) CCDC53 PF10152.9 RLN98891.1 - 0.046 14.1 2.1 0.062 13.7 2.1 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF5344 PF17279.2 RLN98891.1 - 0.072 13.7 0.3 0.072 13.7 0.3 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5344) Mito_fiss_reg PF05308.11 RLN98891.1 - 0.11 12.6 6.4 0.13 12.3 6.4 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Pneumo_att_G PF05539.11 RLN98891.1 - 2.4 7.7 10.7 2.7 7.5 10.7 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G GCOM2 PF15328.6 RLN98891.1 - 2.9 8.2 6.1 3.6 7.9 6.1 1.1 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 DUF3138 PF11336.8 RLN98891.1 - 5.7 5.4 9.8 0.035 12.7 1.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) TPR_14 PF13428.6 RLN98892.1 - 0.34 11.9 5.9 14 6.9 0.1 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat LOR PF04525.12 RLN98893.1 - 2.2e-06 27.4 0.0 4.1e-06 26.5 0.0 1.5 2 0 0 2 2 2 1 LURP-one-related LOR PF04525.12 RLN98895.1 - 0.0095 15.5 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 LURP-one-related WD40 PF00400.32 RLN98896.1 - 0.0044 17.8 8.1 0.11 13.4 0.1 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 RLN98897.1 - 1.8e-22 79.9 0.0 2.3e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN98897.1 - 3.5e-15 56.1 0.0 4.8e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain 2OG-FeII_Oxy_2 PF13532.6 RLN98898.1 - 8.8e-08 32.6 0.0 9.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_16 PF10294.9 RLN98899.1 - 8.2e-27 94.0 0.0 1.2e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 RLN98899.1 - 4.9e-08 32.7 0.0 1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 RLN98899.1 - 0.00021 20.9 0.0 0.00031 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 RLN98899.1 - 0.00043 20.9 0.0 0.006 17.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 RLN98899.1 - 0.00061 19.7 0.0 0.00096 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 RLN98899.1 - 0.0013 18.4 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 RLN98899.1 - 0.011 15.5 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_11 PF08241.12 RLN98899.1 - 0.051 14.2 0.0 0.18 12.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 RLN98899.1 - 0.098 12.5 0.1 0.5 10.2 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain bZIP_2 PF07716.15 RLN98900.1 - 1.3 9.1 6.1 3 8.0 6.1 1.6 1 0 0 1 1 1 0 Basic region leucine zipper BUD22 PF09073.10 RLN98901.1 - 0.13 11.6 17.1 0.17 11.2 17.1 1.1 1 0 0 1 1 1 0 BUD22 CDC27 PF09507.10 RLN98901.1 - 0.21 10.9 16.2 0.27 10.6 16.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.12 RLN98901.1 - 0.48 8.6 18.3 0.59 8.3 18.3 1.1 1 0 0 1 1 1 0 Nop14-like family BNIP2 PF12496.8 RLN98901.1 - 0.52 10.8 7.2 0.78 10.2 7.2 1.3 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 SDA1 PF05285.12 RLN98901.1 - 0.65 9.4 20.1 0.79 9.1 20.1 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 RLN98901.1 - 0.76 7.8 19.9 0.95 7.5 19.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi TT_ORF2 PF02957.15 RLN98901.1 - 0.91 10.5 7.1 1.7 9.6 7.1 1.4 1 0 0 1 1 1 0 TT viral ORF2 SURF2 PF05477.11 RLN98901.1 - 1.1 8.9 10.7 1.7 8.2 10.7 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) PPL5 PF18168.1 RLN98901.1 - 1.8 7.8 6.0 2.6 7.3 6.0 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Sec62 PF03839.16 RLN98901.1 - 1.9 8.0 7.9 2.7 7.5 7.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 FYDLN_acid PF09538.10 RLN98901.1 - 5.4 7.7 19.4 9.2 7.0 19.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Paramyxo_ncap PF00973.19 RLN98901.1 - 6.2 5.6 5.8 8.1 5.2 5.8 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF2457 PF10446.9 RLN98901.1 - 8.4 5.4 22.3 11 5.0 22.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CLPTM1 PF05602.12 RLN98902.1 - 5.9e-34 117.8 0.0 9.1e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Exo_endo_phos PF03372.23 RLN98904.1 - 3.9e-08 33.1 0.0 2.3e-07 30.6 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 RLN98907.1 - 8e-33 113.9 0.0 7.2e-21 74.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RLN98907.1 - 1.1e-10 41.3 0.0 6.6e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 RLN98907.1 - 0.24 10.3 0.0 0.37 9.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 RLN98908.1 - 7.6e-05 22.2 0.1 0.00018 20.9 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain DUF5039 PF16442.5 RLN98908.1 - 0.074 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) cNMP_binding PF00027.29 RLN98909.1 - 1.5e-39 133.9 0.0 4.9e-19 68.2 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain ATP-synt_DE_N PF02823.16 RLN98909.1 - 0.028 14.3 0.0 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF5586 PF17824.1 RLN98909.1 - 0.039 13.1 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5586) Dpy-30 PF05186.13 RLN98909.1 - 0.11 12.2 0.2 0.25 11.0 0.2 1.6 1 0 0 1 1 1 0 Dpy-30 motif Efg1 PF10153.9 RLN98910.1 - 5.4e-13 49.3 5.3 5.4e-13 49.3 5.3 3.7 3 1 1 4 4 4 2 rRNA-processing protein Efg1 CCDC117 PF15810.5 RLN98910.1 - 0.063 13.6 0.2 0.063 13.6 0.2 2.7 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 117 DEAD PF00270.29 RLN98911.1 - 4e-47 160.2 0.0 2.5e-46 157.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RLN98911.1 - 2.6e-33 114.7 0.4 6.1e-33 113.5 0.2 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RLN98911.1 - 0.0009 19.3 0.0 0.0028 17.7 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 RLN98911.1 - 0.01 15.1 0.1 0.015 14.5 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Hydrolase_like PF13242.6 RLN98912.1 - 9.4e-12 44.8 0.1 1.2e-11 44.5 0.1 1.2 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 RLN98912.1 - 0.09 12.9 0.2 0.13 12.3 0.2 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase IRK_C PF17655.1 RLN98913.1 - 4.7e-28 98.0 1.0 6e-13 48.8 0.0 3.3 3 0 0 3 3 3 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 RLN98913.1 - 2.5e-14 53.3 23.1 2.1e-06 27.6 0.7 4.1 2 2 1 3 3 3 3 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 RLN98913.1 - 3.4e-12 46.1 23.5 1.4e-06 28.2 7.6 2.5 2 0 0 2 2 2 2 Ion channel Ost5 PF05251.12 RLN98913.1 - 3.9 7.8 7.3 5.6 7.3 0.8 3.5 3 0 0 3 3 3 0 Oligosaccharyltransferase subunit 5 DUF974 PF06159.13 RLN98914.1 - 3.1e-43 148.4 0.0 2.4e-42 145.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF974) Trs65 PF12735.7 RLN98914.1 - 2.5e-05 23.9 1.1 0.071 12.5 0.1 2.3 1 1 1 2 2 2 2 TRAPP trafficking subunit Trs65 Transglut_C PF00927.22 RLN98914.1 - 0.07 13.3 0.1 0.44 10.7 0.1 2.1 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain Proteasome PF00227.26 RLN98915.1 - 1e-21 77.3 0.1 2.9e-21 75.8 0.1 1.6 1 1 0 1 1 1 1 Proteasome subunit HTH_45 PF14947.6 RLN98915.1 - 0.1 12.6 0.1 0.25 11.4 0.0 1.6 2 0 0 2 2 2 0 Winged helix-turn-helix FHA PF00498.26 RLN98916.1 - 2e-23 82.5 0.0 6.1e-09 36.1 0.0 4.2 4 0 0 4 4 4 3 FHA domain Yop-YscD_cpl PF16697.5 RLN98916.1 - 5.2e-20 71.6 0.0 2.2e-09 37.5 0.0 3.8 3 0 0 3 3 3 3 Inner membrane component of T3SS, cytoplasmic domain cNMP_binding PF00027.29 RLN98916.1 - 2.9e-11 43.3 1.6 4.1e-10 39.6 0.0 3.7 6 0 0 6 6 6 1 Cyclic nucleotide-binding domain Helicase_C PF00271.31 RLN98917.1 - 6.6e-20 71.5 0.1 1.9e-19 70.1 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Phytochelatin_C PF09328.10 RLN98917.1 - 0.034 13.5 0.1 0.043 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) DEAD PF00270.29 RLN98918.1 - 1e-39 136.1 0.0 1.4e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 RLN98918.1 - 0.0067 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RLN98918.1 - 0.019 15.3 0.0 0.037 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain T4SS-DNA_transf PF02534.14 RLN98918.1 - 0.043 12.6 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Ank_5 PF13857.6 RLN98919.1 - 9.8e-07 28.9 0.0 2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN98919.1 - 3.9e-06 27.4 0.0 8.1e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) COX6A PF02046.15 RLN98919.1 - 5.2e-06 26.9 0.0 9.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Ank_4 PF13637.6 RLN98919.1 - 6.5e-05 23.4 0.0 0.0002 21.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 RLN98919.1 - 0.00017 21.9 0.1 0.0013 19.1 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 RLN98919.1 - 0.00098 19.4 0.0 0.005 17.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Branch_AA_trans PF05525.13 RLN98919.1 - 0.14 11.1 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Branched-chain amino acid transport protein Lipase_3 PF01764.25 RLN98920.1 - 4.5e-27 94.6 0.0 4.9e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 RLN98920.1 - 1.2e-05 24.7 0.0 1.5e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 RLN98920.1 - 2.2e-05 24.2 0.0 2.3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 RLN98920.1 - 0.0018 18.9 0.0 0.0018 18.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 RLN98920.1 - 0.0035 17.0 0.0 0.0041 16.8 0.0 1.1 1 0 0 1 1 1 1 Putative esterase DUF900 PF05990.12 RLN98920.1 - 0.0043 16.6 0.0 0.0046 16.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 RLN98920.1 - 0.0057 16.4 0.0 0.0066 16.2 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 RLN98920.1 - 0.014 15.1 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 RLN98920.1 - 0.039 14.1 0.0 0.047 13.8 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 RLN98920.1 - 0.094 12.5 0.1 0.17 11.7 0.1 1.4 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF2048 PF09752.9 RLN98920.1 - 0.14 11.3 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Ribosomal_L5_C PF00673.21 RLN98921.1 - 1.2e-21 76.6 0.0 1.5e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Amidohydro_1 PF01979.20 RLN98922.1 - 7.5e-18 65.0 0.2 1e-17 64.5 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 RLN98922.1 - 2.6e-06 27.4 0.0 6.7e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase ComA PF02679.15 RLN98922.1 - 0.091 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Ank_2 PF12796.7 RLN98923.1 - 9.8e-32 109.4 19.1 1.2e-07 32.2 1.3 7.0 2 1 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN98923.1 - 1.3e-30 105.4 23.1 3.1e-05 24.4 0.1 11.2 7 3 6 13 13 13 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN98923.1 - 4.7e-22 77.8 24.3 0.062 13.6 0.3 13.0 9 2 4 13 13 13 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN98923.1 - 2.5e-15 55.0 15.6 0.67 10.7 0.1 12.9 12 2 2 14 14 14 3 Ankyrin repeat Ank PF00023.30 RLN98923.1 - 0.00037 20.8 19.1 7.4 7.2 0.8 10.0 7 4 0 7 7 7 2 Ankyrin repeat Tet_JBP PF12851.7 RLN98923.1 - 0.046 13.1 0.0 0.17 11.2 0.0 1.6 1 1 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily DUF1484 PF07363.11 RLN98923.1 - 0.13 13.3 0.2 0.73 10.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1484) DEAD_2 PF06733.15 RLN98924.1 - 1.9e-50 170.9 0.3 5.5e-50 169.4 0.1 2.0 2 0 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.6 RLN98924.1 - 4e-41 141.0 0.0 8.1e-41 140.0 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 RLN98924.1 - 5e-36 124.2 1.3 4.9e-30 104.6 0.5 3.0 2 1 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 RLN98924.1 - 8.3e-07 29.2 0.0 9.9e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RLN98924.1 - 0.00015 21.6 0.2 0.013 15.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 RLN98924.1 - 0.031 13.0 0.0 2.8 6.6 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain DUF2075 PF09848.9 RLN98924.1 - 0.048 12.9 0.0 4.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 RLN98924.1 - 0.17 11.3 0.1 3.8 6.9 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein zf-TRAF_2 PF15965.5 RLN98925.1 - 1e-07 32.3 1.0 0.0011 19.4 0.1 2.3 2 0 0 2 2 2 2 TRAF-like zinc-finger PAP_assoc PF03828.19 RLN98925.1 - 1.5e-05 25.1 0.0 0.0017 18.5 0.0 2.7 2 0 0 2 2 2 1 Cid1 family poly A polymerase zf-TRAF PF02176.18 RLN98925.1 - 0.0041 17.8 2.3 0.44 11.3 0.2 2.7 2 0 0 2 2 2 1 TRAF-type zinc finger NTP_transf_2 PF01909.23 RLN98925.1 - 0.01 16.1 0.3 0.035 14.4 0.0 2.0 2 0 0 2 2 2 0 Nucleotidyltransferase domain Sina PF03145.16 RLN98925.1 - 0.044 13.7 1.4 4.1 7.3 0.1 2.3 2 0 0 2 2 2 0 Seven in absentia protein family Polbeta PF18765.1 RLN98925.1 - 0.06 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Ank_2 PF12796.7 RLN98926.1 - 8.4e-31 106.4 6.5 1.6e-05 25.4 0.3 6.7 3 2 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN98926.1 - 1.3e-29 102.2 16.9 8.6e-05 23.0 0.1 11.2 6 4 5 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN98926.1 - 2.7e-19 69.0 26.7 0.068 13.5 0.2 13.7 7 3 9 16 16 16 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN98926.1 - 9.4e-13 47.1 8.6 16 6.5 0.0 13.7 16 1 1 17 17 17 1 Ankyrin repeat DUF249 PF03158.13 RLN98926.1 - 0.0037 17.0 0.7 2.3 7.9 0.0 3.3 3 1 0 3 3 3 2 Multigene family 530 protein Ank PF00023.30 RLN98926.1 - 0.029 14.8 11.4 40 4.9 0.0 8.6 12 1 1 13 13 13 0 Ankyrin repeat Ank_2 PF12796.7 RLN98927.1 - 4.3e-29 100.9 0.0 6.4e-06 26.7 0.0 6.1 2 1 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RLN98927.1 - 5.8e-28 96.9 5.8 1.6e-06 28.5 0.1 8.4 5 5 2 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RLN98927.1 - 6.3e-25 86.9 11.5 0.00025 21.3 0.1 11.9 8 3 4 12 12 12 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN98927.1 - 1.5e-16 58.8 3.5 3.3 8.6 0.0 11.6 13 0 0 13 13 13 3 Ankyrin repeat Ank PF00023.30 RLN98927.1 - 0.0005 20.4 6.5 70 4.1 0.1 7.4 4 3 1 5 5 5 0 Ankyrin repeat DUF1843 PF08898.10 RLN98927.1 - 0.27 11.7 1.4 78 3.9 0.0 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) Staph_opine_DH PF10100.9 RLN98927.1 - 0.3 9.7 0.0 1 7.9 0.0 1.7 2 0 0 2 2 2 0 Staphylopine dehydrogenase Ribosomal_60s PF00428.19 RLN98931.1 - 4.6e-14 52.8 13.0 5.1e-14 52.6 13.0 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein NRD1_2 PF01995.16 RLN98931.1 - 0.11 11.8 0.1 0.12 11.6 0.1 1.0 1 0 0 1 1 1 0 NrpR regulatory domains NRD1 and 2 LSM PF01423.22 RLN98932.1 - 1.8e-18 66.0 0.0 2.5e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RLN98932.1 - 0.0017 18.4 0.0 0.0024 18.0 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain PNISR PF15996.5 RLN98933.1 - 4.8 7.4 6.6 0.46 10.7 1.1 2.0 2 1 0 2 2 2 0 Arginine/serine-rich protein PNISR Ribosomal_S17 PF00366.20 RLN98934.1 - 2.4e-29 101.2 1.3 3.1e-29 100.9 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Prp18 PF02840.15 RLN98934.1 - 0.00014 21.9 0.0 0.00019 21.5 0.0 1.2 1 0 0 1 1 1 1 Prp18 domain zf-HIT PF04438.16 RLN98936.1 - 0.98 9.3 11.5 1.5 8.8 11.5 1.3 1 0 0 1 1 1 0 HIT zinc finger TPR_1 PF00515.28 RLN98937.1 - 0.00055 19.6 3.4 0.16 11.9 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RLN98937.1 - 0.0029 17.6 6.4 0.0072 16.4 0.1 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat Peptidase_Mx PF15887.5 RLN98937.1 - 0.029 13.8 0.3 0.029 13.8 0.3 1.8 2 0 0 2 2 2 0 Putative zinc-binding metallo-peptidase TPR_8 PF13181.6 RLN98937.1 - 0.091 13.0 2.5 1.9 8.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2481 PF10654.9 RLN98937.1 - 0.12 12.4 0.2 0.89 9.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2481) CHD5 PF04420.14 RLN98938.1 - 9e-08 32.1 5.6 1.3e-06 28.3 5.6 2.0 1 1 0 1 1 1 1 CHD5-like protein Efg1 PF10153.9 RLN98938.1 - 0.059 13.7 0.0 0.076 13.4 0.0 1.2 1 0 0 1 1 1 0 rRNA-processing protein Efg1 Reovirus_Mu2 PF07781.11 RLN98938.1 - 0.14 10.4 0.0 0.18 10.1 0.0 1.0 1 0 0 1 1 1 0 Reovirus minor core protein Mu-2 Ubiquitin_2 PF14560.6 RLN98939.1 - 4.3e-25 88.0 0.0 7.7e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 RLN98939.1 - 1.3e-20 73.2 2.7 2e-20 72.5 2.7 1.3 1 0 0 1 1 1 1 CAP-Gly domain RVT_1 PF00078.27 RLN98941.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Tub PF01167.18 RLN98943.1 - 1.7e-31 109.9 0.0 1.6e-30 106.7 0.0 2.1 1 1 0 1 1 1 1 Tub family Macoilin PF09726.9 RLN98943.1 - 0.9 8.0 5.2 1.1 7.8 5.2 1.1 1 0 0 1 1 1 0 Macoilin family TMEM154 PF15102.6 RLN98944.1 - 0.99 9.3 0.0 0.99 9.3 0.0 8.2 3 2 2 5 5 5 0 TMEM154 protein family BT1 PF03092.16 RLN98945.1 - 9.7e-10 37.3 3.9 6.5e-09 34.6 0.8 2.1 2 0 0 2 2 2 2 BT1 family PUCC PF03209.15 RLN98945.1 - 9.9e-08 31.4 0.2 1.7e-07 30.6 0.2 1.3 1 0 0 1 1 1 1 PUCC protein CclA_1 PF16942.5 RLN98945.1 - 1.7 9.0 6.3 0.84 9.9 0.9 2.6 2 1 0 2 2 2 0 Putative cyclic bacteriocin F5_F8_type_C PF00754.25 RLN98947.1 - 8.9e-07 29.1 0.1 1.3e-06 28.6 0.1 1.2 1 0 0 1 1 1 1 F5/8 type C domain FAM184 PF15665.5 RLN98948.1 - 2e-40 138.9 43.7 2e-40 138.9 43.7 8.7 1 1 7 8 8 8 5 Family with sequence similarity 184, A and B PCI PF01399.27 RLN98949.1 - 1.9e-13 50.8 0.2 4.3e-13 49.7 0.2 1.6 1 0 0 1 1 1 1 PCI domain CSN4_RPN5_eIF3a PF18420.1 RLN98949.1 - 0.00051 20.1 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 CSN4/RPN5/eIF3a helix turn helix domain RPN7 PF10602.9 RLN98949.1 - 0.00096 18.9 0.3 0.0015 18.3 0.3 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 Glyco_transf_22 PF03901.17 RLN98950.1 - 4.6e-79 266.6 22.5 5.6e-79 266.3 22.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3272 PF11676.8 RLN98950.1 - 0.018 15.3 0.4 0.045 14.0 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3272) LSM PF01423.22 RLN98951.1 - 5.2e-20 70.9 0.2 6.5e-20 70.6 0.2 1.1 1 0 0 1 1 1 1 LSM domain zf-CCHC PF00098.23 RLN98952.1 - 3.1e-23 80.7 48.2 1.5e-05 24.9 0.8 7.2 7 0 0 7 7 7 5 Zinc knuckle zf-CCHC_4 PF14392.6 RLN98952.1 - 3.9e-06 26.5 42.8 0.026 14.3 0.1 7.2 6 1 1 7 7 7 6 Zinc knuckle zf-C2HC5 PF06221.13 RLN98952.1 - 0.0071 16.3 1.4 0.0071 16.3 1.4 4.5 4 1 2 6 6 6 1 Putative zinc finger motif, C2HC5-type zf-CCHC_5 PF14787.6 RLN98952.1 - 0.017 14.8 5.5 0.017 14.8 5.5 6.0 6 0 0 6 6 6 0 GAG-polyprotein viral zinc-finger Pectate_lyase PF03211.13 RLN98953.1 - 5.3e-06 26.1 0.1 5.3e-06 26.1 0.1 2.3 2 0 0 2 2 2 1 Pectate lyase Ferric_reduct PF01794.19 RLN98954.1 - 1.8e-19 70.1 16.6 1.8e-19 70.1 16.6 3.0 3 1 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 RLN98954.1 - 3.6e-10 40.2 0.0 6.5e-10 39.3 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 RLN98954.1 - 1.1e-09 38.3 0.0 3.4e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain DUF5079 PF16882.5 RLN98954.1 - 0.097 12.5 0.1 0.097 12.5 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF5079) NAD_binding_1 PF00175.21 RLN98954.1 - 0.13 13.0 0.0 0.28 11.8 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain RNA_pol_Rpb1_5 PF04998.17 RLN98955.1 - 5.8e-85 285.0 0.1 1.2e-84 283.9 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 RLN98955.1 - 1e-84 284.5 0.0 2e-84 283.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 RLN98955.1 - 6.2e-77 257.5 0.1 1.2e-76 256.5 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 RLN98955.1 - 1.6e-37 128.8 0.0 1.4e-36 125.9 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 RLN98955.1 - 2.1e-27 95.2 0.0 5e-27 94.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 NARG2_C PF10505.9 RLN98956.1 - 1.7e-07 31.0 0.0 1.6e-05 24.5 0.0 2.3 1 1 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus Pkinase_Tyr PF07714.17 RLN98958.1 - 3.1e-38 131.5 0.0 5.1e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RLN98958.1 - 4.6e-35 121.2 0.0 8.1e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 RLN98958.1 - 3.4e-22 78.5 0.2 2.7e-10 40.6 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RLN98958.1 - 1.6e-21 76.7 0.9 3.2e-11 43.6 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 RLN98958.1 - 9.1e-19 67.0 2.8 6.3e-05 23.2 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 RLN98958.1 - 2.5e-16 59.5 3.4 3.2e-05 24.1 0.2 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RLN98958.1 - 3e-16 57.9 1.5 6.9e-05 23.0 0.1 5.1 4 0 0 4 4 4 3 Ankyrin repeat APH PF01636.23 RLN98958.1 - 0.016 15.2 0.3 0.29 11.0 0.0 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 RLN98958.1 - 0.025 13.9 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like XRN1_D1 PF18332.1 RLN98959.1 - 1.5e-21 77.1 0.0 3.7e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 RLN98959.1 - 6.4e-17 61.4 0.2 1.3e-16 60.4 0.2 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D2_D3 PF18334.1 RLN98959.1 - 2.1e-07 31.0 0.2 8.9e-07 29.0 0.0 2.2 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain CCDC23 PF15674.5 RLN98959.1 - 0.00028 20.8 14.4 0.0008 19.4 14.4 1.8 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 23 60KD_IMP PF02096.20 RLN98961.1 - 7.5e-25 87.7 1.9 9.5e-25 87.4 1.9 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Transketolase_N PF00456.21 RLN98962.1 - 1.7e-43 148.9 0.0 1.9e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Terpene_synth PF01397.21 RLN98962.1 - 0.042 13.5 0.0 0.051 13.3 0.0 1.1 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain CGI-121 PF08617.10 RLN98963.1 - 2.9e-37 128.3 0.0 3.4e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 RPAP3_C PF13877.6 RLN98964.1 - 1.1e-19 70.8 0.0 2.3e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 RLN98964.1 - 1.1e-19 69.3 0.2 9e-05 22.1 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RLN98964.1 - 1.8e-12 46.4 0.6 0.0017 18.3 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RLN98964.1 - 2.8e-08 33.3 0.9 2.6e-05 23.8 0.1 2.9 3 1 1 4 4 4 2 TPR repeat TPR_8 PF13181.6 RLN98964.1 - 1.5e-07 31.0 0.0 0.1 12.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 RLN98964.1 - 1.9e-07 31.0 1.3 0.0074 16.6 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 RLN98964.1 - 3.2e-07 30.9 4.0 1.8e-05 25.3 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 RLN98964.1 - 4e-06 26.9 1.5 0.002 18.3 0.4 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN98964.1 - 0.00052 20.5 0.2 0.0021 18.5 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 RLN98964.1 - 0.0011 18.8 0.4 0.57 10.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN98964.1 - 0.0021 18.3 0.2 0.36 11.1 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN98964.1 - 0.0039 17.9 0.8 13 7.0 0.0 3.6 1 1 2 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RLN98964.1 - 0.18 11.9 1.2 6.4 6.9 0.1 2.9 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Vps39_2 PF10367.9 RLN98965.1 - 8.8e-29 100.2 0.0 2.1e-28 99.0 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 RLN98965.1 - 1.2e-15 57.8 0.0 1.9e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 CNH domain Vps39_1 PF10366.9 RLN98965.1 - 0.00036 20.8 0.0 0.0075 16.5 0.0 3.1 3 1 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 RLN98965.1 - 0.0021 18.0 0.1 0.18 11.7 0.0 3.4 3 1 0 3 3 3 1 Region in Clathrin and VPS TPR_2 PF07719.17 RLN98965.1 - 0.086 13.0 0.2 2.6 8.4 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DHC_N1 PF08385.12 RLN98967.1 - 2.8e-170 567.7 11.7 2.8e-170 567.7 11.7 3.5 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 RLN98967.1 - 2.6e-149 496.6 0.0 8.9e-149 494.9 0.0 2.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RLN98967.1 - 4.3e-125 417.9 13.8 4.3e-125 417.9 13.8 4.9 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RLN98967.1 - 1.2e-95 319.8 0.0 4.6e-95 317.9 0.0 2.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RLN98967.1 - 7.7e-86 286.8 2.5 7.7e-86 286.8 2.5 2.8 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 RLN98967.1 - 3.4e-72 241.8 0.1 3.9e-67 225.3 0.0 3.6 3 0 0 3 3 3 2 P-loop containing dynein motor region MT PF12777.7 RLN98967.1 - 2.9e-56 191.0 9.3 2.2e-54 184.8 12.0 2.3 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 RLN98967.1 - 1.8e-27 96.0 0.1 1.3e-26 93.2 0.0 2.8 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RLN98967.1 - 2.8e-23 82.4 0.0 1.3e-07 31.7 0.0 5.2 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 RLN98967.1 - 8.8e-15 54.7 0.1 3.1e-13 49.8 0.0 3.7 5 0 0 5 5 3 1 AAA+ lid domain AAA PF00004.29 RLN98967.1 - 1.1e-08 35.6 1.5 0.099 13.1 0.0 5.9 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RLN98967.1 - 7.2e-08 32.8 0.1 1 9.6 0.0 5.3 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 RLN98967.1 - 2.5e-07 31.2 7.1 0.9 9.9 0.0 7.0 6 1 0 6 6 5 2 AAA ATPase domain UPF0242 PF06785.11 RLN98967.1 - 0.00018 21.7 2.7 0.00018 21.7 2.7 4.5 4 0 0 4 4 4 1 Uncharacterised protein family (UPF0242) N-terminus FtsK_SpoIIIE PF01580.18 RLN98967.1 - 0.00051 19.5 0.1 0.0048 16.3 0.0 2.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family ADIP PF11559.8 RLN98967.1 - 0.0013 18.9 10.5 0.0013 18.9 10.5 3.4 3 0 0 3 3 2 1 Afadin- and alpha -actinin-Binding AAA_18 PF13238.6 RLN98967.1 - 0.0019 18.8 0.1 0.38 11.3 0.0 4.5 4 0 0 4 4 4 1 AAA domain Tropomyosin_1 PF12718.7 RLN98967.1 - 0.0021 18.2 8.9 0.0021 18.2 8.9 4.6 6 0 0 6 6 3 1 Tropomyosin like RNA_helicase PF00910.22 RLN98967.1 - 0.0084 16.5 0.0 4.8 7.6 0.0 3.5 3 0 0 3 3 3 1 RNA helicase Rad17 PF03215.15 RLN98967.1 - 0.011 15.6 0.8 6.6 6.6 0.0 3.8 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_30 PF13604.6 RLN98967.1 - 0.023 14.4 2.4 2.9 7.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 RLN98967.1 - 0.023 14.4 0.0 7.1 6.3 0.0 3.1 3 0 0 3 3 2 0 Sigma-54 interaction domain PhoH PF02562.16 RLN98967.1 - 0.065 12.7 0.5 0.71 9.3 0.0 2.7 2 0 0 2 2 2 0 PhoH-like protein Dynein_heavy PF03028.15 RLN98967.1 - 0.066 13.3 0.0 0.68 10.0 0.0 2.8 2 0 0 2 2 2 0 Dynein heavy chain region D6 P-loop domain Yuri_gagarin PF15934.5 RLN98967.1 - 0.071 12.9 4.9 0.12 12.2 1.4 3.0 2 0 0 2 2 2 0 Yuri gagarin T2SSE PF00437.20 RLN98967.1 - 0.071 12.1 0.3 3.9 6.4 0.1 2.9 2 0 0 2 2 2 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 RLN98967.1 - 0.1 12.5 0.5 1.2 9.0 0.0 2.9 3 0 0 3 3 2 0 RsgA GTPase DUF4763 PF15960.5 RLN98967.1 - 0.26 10.6 5.2 2.1 7.6 5.2 2.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) TolA_bind_tri PF16331.5 RLN98967.1 - 0.5 10.5 8.4 2.2 8.4 6.7 3.2 2 0 0 2 2 2 0 TolA binding protein trimerisation ABC_tran PF00005.27 RLN98967.1 - 0.53 10.8 3.8 4.6 7.8 0.0 4.1 4 0 0 4 4 2 0 ABC transporter DUF2730 PF10805.8 RLN98967.1 - 4.3 7.5 10.4 0.8 9.8 0.9 4.5 4 1 0 4 4 3 0 Protein of unknown function (DUF2730) Bacillus_HBL PF05791.11 RLN98967.1 - 9.1 6.1 13.6 0.4 10.5 4.2 3.8 3 0 0 3 3 2 0 Bacillus haemolytic enterotoxin (HBL) Myb_DNA-bind_4 PF13837.6 RLN98968.1 - 0.0036 17.6 1.0 0.0036 17.6 1.0 2.1 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain AT_hook PF02178.19 RLN98968.1 - 0.12 12.3 8.1 3.5 7.8 0.1 3.1 2 0 0 2 2 2 0 AT hook motif HECT PF00632.25 RLN98969.1 - 4.6e-62 210.3 0.0 6.6e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-MYND PF01753.18 RLN98969.1 - 1.5e-08 34.6 9.1 1.5e-08 34.6 9.1 2.6 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 RLN98969.1 - 3.3e-05 24.1 7.2 9.8e-05 22.6 7.2 1.9 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 RLN98969.1 - 0.6 10.0 10.3 1.7 8.6 10.3 1.8 1 0 0 1 1 1 0 HIT zinc finger CTU2 PF10288.9 RLN98969.1 - 4.1 7.7 7.0 0.26 11.5 0.6 2.3 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 HECT PF00632.25 RLN98971.1 - 2.1e-67 227.8 0.0 3.3e-67 227.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 RLN98971.1 - 0.32 10.3 1.3 0.59 9.5 0.8 1.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others HECT PF00632.25 RLN98972.1 - 9.4e-70 235.5 0.0 1.2e-69 235.2 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) APG17 PF04108.12 RLN98973.1 - 2e-06 27.2 0.1 2e-06 27.2 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 TK PF00265.18 RLN98974.1 - 6.8e-24 84.7 1.4 4.6e-22 78.7 1.4 2.0 1 1 0 1 1 1 1 Thymidine kinase HTH_Tnp_Tc5 PF03221.16 RLN98975.1 - 6.7e-11 42.1 0.0 3.1e-10 39.9 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 RLN98975.1 - 2.6e-06 27.1 1.0 5.4e-06 26.0 1.0 1.5 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 RLN98976.1 - 3.1e-13 49.5 1.2 3.9e-12 46.0 0.0 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 RLN98976.1 - 0.001 18.8 0.3 0.0022 17.7 0.3 1.6 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_32 PF13565.6 RLN98976.1 - 0.0089 16.6 0.5 0.0089 16.6 0.5 3.2 3 0 0 3 3 3 1 Homeodomain-like domain CENP-B_N PF04218.13 RLN98976.1 - 0.023 14.3 0.8 0.19 11.4 0.8 2.4 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain MSV199 PF10553.9 RLN98977.1 - 0.02 15.1 0.0 0.37 11.1 0.0 2.2 2 0 0 2 2 2 0 MSV199 domain UPF0767 PF15990.5 RLN98978.1 - 0.4 10.8 1.2 1.5 9.0 0.0 2.3 3 0 0 3 3 3 0 UPF0767 family Spore_III_AB PF09548.10 RLN98978.1 - 1.2 9.2 5.8 9.4 6.3 3.2 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) MMS1_N PF10433.9 RLN98979.1 - 2.8e-107 359.3 0.1 6.4e-107 358.2 0.1 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 RLN98979.1 - 2.6e-78 263.6 0.0 2.1e-77 260.6 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region DUF4780 PF16012.5 RLN98979.1 - 0.16 11.4 0.0 0.47 9.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4780) Sigma70_ECF PF07638.11 RLN98983.1 - 0.65 9.9 4.9 0.77 9.6 1.6 2.2 2 0 0 2 2 2 0 ECF sigma factor BT1 PF03092.16 RLN98985.1 - 4.1e-10 38.5 5.4 2.7e-08 32.5 0.6 2.9 2 1 0 2 2 2 2 BT1 family E1-E2_ATPase PF00122.20 RLN98985.1 - 5.3 6.5 6.4 8.8 5.8 1.1 2.8 2 0 0 2 2 2 0 E1-E2 ATPase Cluap1 PF10234.9 RLN98986.1 - 0.026 13.9 0.6 0.085 12.2 0.5 1.9 1 1 1 2 2 2 0 Clusterin-associated protein-1 EamA PF00892.20 RLN98987.1 - 1.4e-14 54.4 33.8 2.3e-07 31.0 9.8 2.4 2 0 0 2 2 2 2 EamA-like transporter family NTP_transf_3 PF12804.7 RLN98987.1 - 1.1e-06 29.2 0.0 4.5e-06 27.1 0.0 2.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 RLN98987.1 - 0.00016 21.3 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase DUF3938 PF13074.6 RLN98987.1 - 0.16 12.2 1.0 0.96 9.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) RRM_1 PF00076.22 RLN98988.1 - 2e-12 46.8 0.0 2.8e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 RLN98988.1 - 0.097 12.7 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 RNA binding domain DUF3932 PF13068.6 RLN98988.1 - 0.24 11.7 0.0 0.33 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) TPR_16 PF13432.6 RLN98989.1 - 5.4e-06 27.0 1.3 1.9e-05 25.2 0.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 RLN98989.1 - 7.8e-06 25.6 1.4 0.47 10.7 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 RLN98989.1 - 0.00026 21.5 0.8 2.7 9.0 0.0 3.8 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RLN98989.1 - 0.00036 20.5 0.6 13 6.3 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 RLN98989.1 - 0.00059 20.3 0.9 0.0095 16.4 0.0 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 RLN98989.1 - 0.0034 16.8 1.2 0.005 16.3 1.2 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_7 PF13176.6 RLN98989.1 - 0.0094 15.9 0.2 8.9 6.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 RLN98989.1 - 0.012 15.9 4.2 3.8 7.9 0.0 3.2 2 2 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RLN98989.1 - 0.015 15.5 1.8 0.42 10.9 0.0 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 YfdX PF10938.8 RLN98989.1 - 0.059 13.3 3.0 0.66 9.9 2.0 2.7 1 1 0 1 1 1 0 YfdX protein Pox_A14 PF05767.12 RLN98990.1 - 0.063 13.4 0.6 0.22 11.7 0.1 2.2 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Med1 PF10744.9 RLN98991.1 - 0.059 12.4 0.1 0.064 12.3 0.1 1.0 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 CRISPR_Cas6 PF10040.9 RLN98991.1 - 0.13 13.0 0.0 0.13 12.9 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated endoribonuclease Cas6 B-block_TFIIIC PF04182.12 RLN98992.1 - 0.00022 21.3 0.0 0.00055 20.0 0.0 1.7 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Oomycete/Nothophytophthora_sp._Chile5-PfChile5v2.0/GCA_001712635.2_PfChile5v2.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Oomycete/Nothophytophthora_sp._Chile5-PfChile5v2.0/GCA_001712635.2_PfChile5v2.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Oomycete/Nothophytophthora_sp._Chile5-PfChile5v2.0/GCA_001712635.2_PfChile5v2.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Oomycete/Nothophytophthora_sp._Chile5-PfChile5v2.0/GCA_001712635.2_PfChile5v2.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 12:41:08 2019 # [ok]